ADC Pool Level 01 Preview 结果审核（PROVISIONAL_NOT_AUTHORIZED_FOR_ADVANCEMENT） - #60
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Result review for gen_iet_adc_pool_level_01_preview_20260805T160125Z, generated under the merged PR #57/#58/#59 contracts on the human lead's ten-constraint instruction. Every artefact is external; this PR adds only a handoff and a worklog entry. The artefact is PROVISIONAL_NOT_AUTHORIZED_FOR_ADVANCEMENT. It is not a formal Level 01 execution result, may not serve as Gate input, may not inform asset decisions and may not enter Level 02. ADC_POOL_LEVEL_01_ACCEPTED still requires all five approvals: SRCADM-01, the EVGAP-01 extraction result and binding, and the EVGAP-02 extraction result and binding. Stated up front because it governs everything else: the preview reads ADC_surfaceome_reference@0.3.0, which has never been reviewed. SRCADM-01 is open and PR #59's admission_record_ref is null. That is precisely why the 22 targets are labelled provisional_surface_eligible rather than eligible_surface_target, and why the whole preview is provisional. The manifest records the source as NOT_ADMITTED_PENDING_SRCADM_01. The quarantined PR #53 and #54 runs are listed as barred inputs with used false. Result: 9 raw contexts, 1 eligible and 8 hold; 41 raw targets, 22 provisional_surface_eligible and 19 hold_surface_evidence; the full 369-pair Raw Enumeration Matrix retained; 22 pairs in HOLD_PENDING_CRC_LINKAGE and 347 in RAW_MATRIX_ONLY; LOCK-03 unresolved for all 369 because EVGAP-02 is not complete; zero active-for-Level-02 and zero exclusions. active equals zero does not mean the pool is empty. It means no pair yet satisfies all three locks while 22 have passed provisional context and target identity and are waiting on CRC linkage. Hold is pending evidence, not a negative. LOCK-01 was evaluated under #59's frozen precedence and the rule split came out 22/6/3/6/0/4, matching that contract's predicted shape item by item. MF-01 is recorded as measured rather than softened: GUCY2C holds on a single independent evidence family, contradicting the earlier multi-model consensus and the quarantined run's Tier A. FAP's likely stromal dominance and the normal-tissue or immune expression of CD274, EGFR and EPCAM are carried forward to T7 and T11 rather than cleared at Level 01. Every row of every TSV carries provisional_only true and may_advance_to_level_02 false, pool_state has no active value at all, and the manifest sets is_formal_level_01_execution_result, may_be_used_as_gate_input and may_be_used_for_asset_decisions to false. All ten instruction constraints were script-verified as PASS. No Gate was run, no score assigned, no ranking, no asset or experimental recommendation, no target or context added, no barred Level 02 file read, and no repository write. The Level 01 binding is untouched and neither EVGAP is lifted. 309 tests pass. Per-file SHA-256 for all seven artefacts is in the handoff. Co-Authored-By: Claude Opus 5 <noreply@anthropic.com>
…eview Both blockers accepted. Both were mine. Blocker 1: the 22 HOLD_PENDING_CRC_LINKAGE rows carried blocking_evidence_gaps EVGAP-02 only. The generator logic was backwards - it read "EVGAP-02 if in_index else EVGAP-01;EVGAP-02" - when those 22 pairs are precisely the ones whose LOCK-01 came from ADC_surfaceome_reference@0.3.0, which has not passed SRCADM-01. PR #59 froze the extraction contract and nothing else: no database approved, no extraction authorised, no gap lifted, no 22/19 verdict accepted. A downstream reader consuming pool_level_01_preview.tsv alone would have concluded LOCK-01 was formally passed with only CRC linkage outstanding. The target table had it right, which makes the inconsistency more misleading than a uniform error would be. All 369 rows now carry EVGAP-01;EVGAP-02, verified at 0 of 369 missing EVGAP-01, and the in-index reason states both pending gaps. Blocker 2: the claim that every TSV carried provisional_only and may_advance_to_level_02 on every row was factually wrong. raw_clinical_contexts.tsv lacked may_advance_to_level_02 and raw_enumeration_matrix.tsv lacked both. Not a wording defect: the Raw Matrix is likely to be read on its own and would be misusable once separated from the manifest. The schema is unified - all four TSVs now carry both columns on every row, with no empty values and a single value each. The non-blocking enhancement is taken too: raw_targets.tsv and pool_level_01_preview.tsv now carry source_admission_status NOT_ADMITTED_PENDING_SRCADM_01, so the governance state travels with the row instead of living only at the manifest top level. Counts are unchanged: 9 contexts, 41 targets, 369 pairs, 22 provisional and 19 hold, 22 HOLD_PENDING_CRC_LINKAGE and 347 RAW_MATRIX_ONLY, LOCK-03 unresolved 369/369, zero active, zero exclusions. The manifest is bumped to revision 2 with the reason recorded; revision 1 checksums are superseded and all seven files were re-hashed. Still no repository write, no Gate, no score, no ranking, no recommendation, no gap lifted and no change to the Level 01 binding. 309 tests pass. Co-Authored-By: Claude Opus 5 <noreply@anthropic.com>
…l-level-01-preview-result # Conflicts: # logs/worklog.md
The reviewer inspected the uploaded ZIP and found it was still revision 1: 22 rows carrying EVGAP-02 alone, two TSVs missing guard columns, and no revision field in the manifest. The ruling is explicit that the fix logic itself is correct and the problem is that the package under review is the wrong version. Accepted, and the failure is mine in the delivery step: after revising to revision 2 I updated the handoff, the PR body and the checksums but never produced a corresponding uploadable package. A result review has to verify the actual files, not the documentation about them; syncing the description without syncing the object under review asks the reviewer to audit something they cannot see. Re-verified the on-disk revision 2 against all six acceptance criteria, all passing: manifest revision 2; the seven SHA-256 values match appendix A exactly; all four TSVs carry both guard columns with sole values true and false at 9, 41, 369 and 369 rows; all 369 pool rows carry EVGAP-01;EVGAP-02; the 22/19, 22/347 and 369-unresolved counts are unchanged; and there is no active state, no accepted label, no Gate score, no T7 validation and no Level 02 advancement, with t7_tumor_surface_validated holding only not_assessed_level_02_scope. Added the packaged artefact at external:result/gen_iet_adc_pool_level_01_preview_20260805T160125Z_revision2.zip, 24904 bytes, SHA-256 8687e8774b53fda1d3a6fdac38fc56cb0cc2fd198677db5a1f7d5d50a449e823, containing exactly the seven output files. Its contents were read back out of the archive to confirm revision 2, the gap string on all 369 rows, and the guard columns. Path and digest are recorded in the handoff so which version was uploaded becomes a checkable fact rather than an assertion. Rule I am holding myself to from here: every revision of an external artefact in a result-review PR must ship a version-stamped package with its own recorded SHA-256. Editing the handoff and the PR body is not delivery. 309 tests pass. No repository write of artefacts, no gap lifted, no change to the Level 01 binding. Co-Authored-By: Claude Opus 5 <noreply@anthropic.com>
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All three blockers accepted. Blocker 1: class D never entered search completeness, and endpoint coverage was left to the executor. The contract said A/B/C are searched per target and D is assessed per pair, but search_complete_definition only required the three source classes per target. Both consequences the reviewer named are real: a subgroup pair could land on L3-03 without D ever being searched, and L3-05's "no class hit" could fire with D unsearched. Separately, peer_reviewed_literature has two endpoints and public_molecular_dataset three, while the contract only demanded source-class coverage, so an executor could query one and stop. per_pair_required_class_d_search now covers all 369 pairs with six recorded fields that also appear in the disposition table, and an incomplete D search forces L3-01 rather than L3-03 or L3-05. Completeness now requires both levels, coverage_unit is endpoint, and every source class declares all_endpoints_required with an explicit minimum_endpoint_set. Blocker 2: nothing tied a disposition row to the evidence rows behind it. With only evidence_row_count, an L3-02 retain could not answer which A/B/C evidence supported it, which D evidence carried a subgroup, or whether other-cancer precedent was present without being counted as linkage. Worse, my test validated the conditionally required columns against the union of both tables, which is precisely what masked this. Evidence rows now carry a unique evidence_id, dispositions carry supporting, class-D and other-cancer reference lists, and evidence_reference_requirements freezes per rule what must and must not be cited, with L3-02 split by context kind. Each conditional block now names its table and the test checks per table instead of the union. Blocker 3: synced origin/main and resolved logs/worklog.md chronologically, with main's 12:45 entry before mine at 13:30. Verified afterwards that the diff against main is still exactly five files, that none of PR #60's preview output leaked in, and that no unrelated contract came with it. One operational mistake of my own, caught and repaired: switching branches to handle PR #60 I ran git stash -u, which swept the uncommitted blocker 1 and 2 YAML edits into the stash, and I did not restore them on returning, so later edits landed on the unrevised file and the tests raised KeyError. Located stash@{0}, discarded the conflicting edit, popped all 133 lines back and redid the work with nothing lost. 338 tests pass. Twelve mutations caught and rolled back exactly. Co-Authored-By: Claude Opus 5 <noreply@anthropic.com>
…l-level-01-preview-result # Conflicts: # logs/worklog.md
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第二轮裁决接受：被审核的结果包版本不匹配，已产出 revision 2 打包。 请复审。
请上传这个包
8687e8774b53fda1d3a6fdac38fc56cb0cc2fd198677db5a1f7d5d50a449e823manifest revision = 2、blocking_evidence_gaps = {'EVGAP-01;EVGAP-02': 369}、四个 TSV 行数 9／41／369／369 且两个 guard 列齐备第二轮裁决（接受）：交付包版本不匹配
你指出的是对的，而且指出了要点：这不是修复逻辑仍有问题，而是被审核的实际结果包版本不匹配。
我在 revision 2 修订后只更新了仓库侧的 handoff、PR 描述与校验和，没有产出一个与之对应的、可上传的结果包。结果审核必须核验实际文件而不是文档对文件的描述——只同步描述而不同步被审对象，等于让审核方审一份看不到的东西。这是交付环节的失误，不是逻辑失误。
按六条验收标准对磁盘上的 revision 2 逐条复核，全部
PASS：revision: 2PASSPASStrue／falsePASS（9／41／369／369）EVGAP-01;EVGAP-02PASS（{'EVGAP-01;EVGAP-02': 369}）PASSPASS（t7_tumor_surface_validated唯一取值not_assessed_level_02_scope）此后我自我约束的规则： 结果审核 PR 每次修订外部产物，都必须同时产出带版本标识的打包并记录其 SHA-256；只改 handoff 与 PR 描述不算完成交付。
第一轮的两条阻断（已修订，内容不变）
70ad9f0（首轮受审6778a6b）gen_iet_adc_pool_level_01_preview_20260805T160125Z，revision 2Ran 309 tests通过、仓库零写入logs/worklog.md阻断 1（接受）：22 个核心 pair 错误丢失了
EVGAP-01生成逻辑写反了。 我的代码是
"EVGAP-02" if in_index else "EVGAP-01;EVGAP-02"——而恰恰是这 22 个 in-index 的 pair，其 LOCK-01 状态来自尚未通过SRCADM-01的ADC_surfaceome_reference@0.3.0，最应该同时带EVGAP-01。PR #59 只冻结了抽取契约：没批准数据库、没授权抽取、没解除
EVGAP-01、没正式接受 22／19 的判定。后果正如你指出的：独立消费
pool_level_01_preview.tsv的下游会误以为 LOCK-01 已正式通过、只剩 CRC linkage 未完成。而 target 表其实正确保留了两个 gap——一进入 pool 行就丢了，这种不一致比统一写错更容易骗过读者。修订：
blocking_evidence_gaps = EVGAP-01;EVGAP-02pool_state_reason改为provisional_context_and_surface_identity_pending_evgap_01_and_crc_linkage_pending_evgap_02EVGAP-01正式接受和EVGAP-02CRC linkage」EVGAP-01的行 0 / 369阻断 2（接受）：机械防护声明与实际文件不一致
revision 1 的实况正如你列的：
provisional_onlymay_advance_to_level_02raw_clinical_contexts.tsvraw_targets.tsvraw_enumeration_matrix.tsvpool_level_01_preview.tsv我的声明是事实错误。 而且不是纯文案问题——Raw Matrix 很可能被下游单独读取，脱离 manifest 后就会被误用。
修订：按你的建议统一 schema，四个 TSV 全部加入两列并逐行填充。
逐个读取校验结果：
provisional_onlymay_advance_to_level_02raw_clinical_contexts.tsv{true}{false}raw_targets.tsv{true}{false}raw_enumeration_matrix.tsv{true}{false}pool_level_01_preview.tsv{true}{false}无空值，取值唯一，全部
PASS。PR body、handoff、report 与实际 schema 已同步一致。非阻断增强（已接受）
raw_targets.tsv与pool_level_01_preview.tsv新增source_admission_status = NOT_ADMITTED_PENDING_SRCADM_01。原先该治理信息只存在于 manifest 顶层，TSV 被单独复制或加载时会丢失。修订未改变的对账
你确认正确的部分全部保持不变：9 contexts、41 targets、369 pairs 无重复、22
provisional_surface_eligible、19hold_surface_evidence、22HOLD_PENDING_CRC_LINKAGE、347RAW_MATRIX_ONLY、LOCK-03 369/369unresolved、may_advance_to_level_02=false369/369、无 active-for-Level-02、#53／#54 仍列 barred inputs、无 Gate score／排序／资产推荐。manifest 升为
revision: 2并写入revision_reason、guard_columns、governance_columns与counts.blocking_evidence_gaps = {'EVGAP-01;EVGAP-02': 369}。外部 worklog 追加 8 条修订记录。产物状态不变
result_status = PROVISIONAL_NOT_AUTHORIZED_FOR_ADVANCEMENT、authorises_level_02 = false、evgap_01_status = pending_source_admission_and_extraction、evgap_02_status = not_completed，另加is_formal_level_01_execution_result: false、may_be_used_as_gate_input: false、may_be_used_for_asset_decisions: false。三条
mandatory_findings不变，含MF-01GUCY2C 落 hold（与此前多模型共识首选及被隔离运行 Tier A 相反，按实测原样写出）。边界不变
仓库零写入（产物全在外部
DATA）；未运行 Gate、未赋分数、未排序、未推荐资产、未给实验建议；未评估 T7；未新增靶点或 context；零排除；未读 #59 禁读的四个 Level 02 文件；未引用被隔离运行任何产物；未解除EVGAP-01或EVGAP-02，未更新 Level 01 binding。一处更正与合并说明
推送前我曾在 PR 描述里写：
docs/architecture/BIOTECH_INFRASTRUCTURE_CATALOG.zh-CN.md有 +1013 行未提交改动、留给人类负责人处置。那个判断不完整。 核实后：人类负责人已把该内容直接提交到main（0190a73docs: add patient-anchored data infrastructure），我工作树里那份副本与main已提交版本逐字节相同，因此丢弃本地副本不损失任何内容，随后由合并main正常带入。75f7e83，其中70ad9f0是修订提交、75f7e83是合并origin/mainlogs/worklog.md冲突按时间顺序解决：我的 12:04 → main 的 12:45 EDT → 我的 14:10，并断言无残留冲突标记、两侧每个条目与每个标题都在70ad9f0与75f7e83之间逐字节相同，唯一的其他非 worklog 差异就是 main 那份 catalog 经合并进入main，本 PR 仍只含两个文件：handoff 与 worklog（git diff --stat origin/main...HEAD已核验）本 PR 不适用
AGENTS.md「审核豁免」，须经 ChatGPTAPPROVE。批准只代表接受这份 provisional preview 作为可审计的中间产物；不批准任何靶点判定、筛选结果、排序或科学结论，不授权进入 Level 02，也不解除任何证据缺口。