Carrick Therapeutics is a clinical-stage biopharmaceutical company headquartered in Boston, Massachusetts, developing novel oncology therapies aimed at improving outcomes for patients with aggressive and treatment-resistant cancers.
Relay Therapeutics is a Cambridge, Massachusetts clinical-stage precision medicines company (NASDAQ: RLAY) using protein motion to drug historically intractable oncology and genetic-disease targets.
Semnur Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing non-opioid pain-management therapies. Its lead program, SP-102 (SEMDEXA), is a novel, non-opioid, preservative-free and particulate-free injectable corticosteroid gel formulation intended to treat moderate-to-severe chronic radicular pain (sciatica).
Pathios Therapeutics is a clinical-stage oncology and immunology drug discovery and development company based in Oxfordshire, United Kingdom, founded in 2017. The company develops small-molecule inhibitors of the pH-sensing G protein-coupled receptor GPR65 to counteract the immunosuppressive tumor microenvironment; its lead asset PTT-4256 is a…
Engrail Therapeutics is a clinical-stage biopharmaceutical company founded in 2019 and focused on precision neuroscience. The company develops innovative, precision-targeted small-molecule therapeutics aimed at the molecular mechanisms and neural circuits underlying nervous system disorders, combining internal discovery with strategic…
Solu Therapeutics is a clinical-stage biotechnology company headquartered in Boston, Massachusetts, pioneering a novel class of antibody therapeutics that unlock cell-surface targets by combining small molecules with effector antibodies through proprietary linker technology.
Compass Therapeutics is a clinical-stage biopharmaceutical company developing proprietary antibody-based therapeutics for the treatment of cancer. Its research is grounded in understanding the tumor microenvironment, designing candidates that optimize the components required for an effective anti-tumor immune response and bridge innate and…
kechowpharma — Kechow Pharma (Shanghai Kezhou Pharmaceutical Co., Ltd.) is a clinical-stage biopharmaceutical company founded in 2014 and headquartered in Shanghai's Zhangjiang High-Tech Park.
Aer Therapeutics is a clinical-stage biopharmaceutical company based in the Research Triangle Park / Raleigh area of North Carolina, developing novel treatments for muco-obstructive lung diseases such as COPD, asthma, cystic fibrosis, and non-CF bronchiectasis. A spinout from Dr.
Vima Therapeutics is a clinical-stage biotechnology company developing novel oral therapies for movement disorders, with a focus on the underlying biology of dystonia and Parkinson's disease.
ArriVent BioPharma is a clinical-stage biopharmaceutical company focused on the identification, development, and commercialization of differentiated medicines to address the unmet medical needs of patients with difficult-to-treat diseases, beginning with cancers.
Basking Biosciences is a clinical-stage biopharmaceutical company in Research Triangle, North Carolina (with operations in Mitchelton, Queensland, Australia) developing novel therapies for life-threatening blood clots.
Zenasbio — Zenas BioPharma is a global clinical-stage biopharmaceutical company focused on developing and delivering transformative treatments for patients with autoimmune and rare diseases. Its lead candidates are obexelimab, a bifunctional monoclonal antibody that inhibits B-cell activity without depleting B cells, and orelabrutinib, an oral…
Escient Pharmaceuticals is a San Diego, California clinical-stage biopharmaceutical company developing first-in-class, oral small-molecule therapeutics targeting Mas-related G protein-coupled receptors (MRGPRs) along the neurosensory-inflammatory axis.
Trishula Therapeutics is a privately held, clinical-stage immuno-oncology company developing cancer immunotherapies that target immune-evasion mechanisms in the tumor microenvironment.
Tenaya Therapeutics is a clinical-stage biotechnology company headquartered in South San Francisco, California, focused on discovering, designing, developing, and delivering potentially curative gene therapies and precision medicines that address the underlying drivers of heart disease.
Areteia Therapeutics was a clinical-stage biotechnology company, formerly based in Chapel Hill, North Carolina, operating in the life-sciences sector. As of the July 2026 enrichment pass the company is no longer operating: areteiatx.com serves only a closure notice directing asset and general inquiries to contact addresses, and the company…
MBX Biosciences is a clinical-stage biopharmaceutical company developing novel precision peptide therapies for endocrine and metabolic disorders, built on its proprietary PEPs platform. Lead programs include canvuparatide (MBX 2109) for hypoparathyroidism, plus MBX 4291, MBX 5765, and MBX 6XXX.
Affinia Therapeutics is a clinical-stage biotechnology company in Waltham, Massachusetts pioneering next-generation adeno-associated virus (AAV) gene therapies. Using AI and structural modeling to rationally design novel capsids that better target tissues for improved safety and effectiveness, Affinia develops therapeutic cargoes for devastating…
Chimerix, Inc. was a biopharmaceutical company headquartered in Durham, North Carolina, focused on developing medicines for serious and life-threatening diseases. It is best known for brincidofovir (TEMBEXA), an antiviral approved by the U.S.
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