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Totus Medicines is a biopharmaceutical company developing precision oral medicines against historically "undruggable" disease targets. The company's OmniDEL discovery platform screens targets in their normal cellular environment to identify potent, selective covalent small molecules, drawing on precedents like penicillin and AZT.
Sciwind Biosciences (Hangzhou Sciwind Biosciences Co., Ltd.) is a commercial-stage biopharmaceutical company headquartered in Hangzhou, China, with a US office in San Ramon, California, focused on discovering, developing, and delivering innovative therapeutics for weight management and metabolic disease.
Nocion Therapeutics is a clinical-stage biopharmaceutical company discovering and developing a novel class of biologically selective charged sodium channel (NaV) blockers designed to selectively silence overactive sensory neurons to relieve chronic cough, pain, itch, and inflammation.
Seismic Therapeutic is a clinical-stage biopharmaceutical company developing transformative biologic medicines for autoimmune and inflammatory diseases. The company pairs structural biology with machine learning through its proprietary IMPACT platform to design multi-functional antibodies and Immunoglobulin Sculpting (IgSc) enzymes across…
Granata Bio is a reproductive-health biopharmaceutical company founded in 2018 and headquartered in the United States, focused on expanding access to fertility and IVF therapeutics across North America.
Braveheart Bio is a late clinical-stage biopharmaceutical company developing novel therapeutics for hypertrophic cardiomyopathy (HCM) and related cardiac conditions. Its lead candidate, BHB-1893, is a selective cardiac myosin inhibitor (licensed as HRS-1893 from Hengrui Pharma) designed to reduce excessive heart-muscle contraction and improve…
kechowpharma — Kechow Pharma (Shanghai Kezhou Pharmaceutical Co., Ltd.) is a clinical-stage biopharmaceutical company founded in 2014 and headquartered in Shanghai's Zhangjiang High-Tech Park.
Aer Therapeutics is a clinical-stage biopharmaceutical company based in the Research Triangle Park / Raleigh area of North Carolina, developing novel treatments for muco-obstructive lung diseases such as COPD, asthma, cystic fibrosis, and non-CF bronchiectasis. A spinout from Dr.
Axcelius I/II is a biopharmaceutical company-creation vehicle backed by Canaan Partners, formed to found and incubate drug-development companies pursuing treatments for cancer, rare diseases, and neurodegenerative disorders.
Barinthus Biotherapeutics plc (Nasdaq: BRNS) is a clinical-stage biopharmaceutical company developing novel immunotherapies designed to guide and reprogram T cells to overcome autoimmunity, inflammatory disease, chronic viral infection, and cancer.
Odyssey Therapeutics is a clinical-stage biopharmaceutical company developing small-molecule and biologic therapeutics for autoimmune, inflammatory, and oncology indications. The company targets upstream immune signaling mechanisms to prevent pathological inflammation rather than only suppressing downstream responses, advancing a pipeline of…
Ark Biopharmaceutical (爱科百发, Ark Biosciences) is a Shanghai-based clinical-stage biopharmaceutical company focused on the discovery and development of innovative therapies for respiratory diseases and pediatric conditions.
Pliant Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery and development of integrin-based therapies for underserved areas of medical need. Leveraging a proprietary integrin drug discovery and delivery platform, its lead program PLN-101095 is a dual-selective avb8/avb1 integrin inhibitor being evaluated in the…
ArriVent BioPharma (NASDAQ: AVBP) is a clinical-stage biopharmaceutical company dedicated to the identification, development, and commercialization of differentiated medicines for the treatment of cancer.
Metsera is a clinical-stage biopharmaceutical company developing injectable and oral therapies for obesity and metabolic diseases, backed by GV and the SoftBank Vision Fund. As of this enrichment pass its corporate domain (metsera.com) issues a 301 redirect to pfizer.com, consistent with Metsera's acquisition by Pfizer.
Shanghai Vitalgen BioPharma Co., Ltd. (Vitalgen), founded in March 2020 and headquartered in Shanghai, China, translates cutting-edge gene delivery and gene editing techniques into clinically effective treatments for patients with unmet medical needs.
CREATE Medicines is a Cambridge, Massachusetts biopharmaceutical company developing in vivo CAR (chimeric antigen receptor) cell therapies using mRNA lipid-nanoparticle (mRNA-LNP) delivery.
Millennium Pharmaceuticals was a biopharmaceutical company based in Cambridge, Massachusetts, focused on oncology and inflammation, best known for developing the cancer drug Velcade (bortezomib).
Arresto Biosciences, Inc. was a privately-held, development-stage biotechnology company headquartered in Palo Alto, California, focused on medicines to treat fibrotic diseases and cancer by targeting enzymes involved in the synthesis of the extracellular matrix.
Roivant Sciences Ltd. (Nasdaq: ROIV) is a commercial-stage biopharmaceutical holding company that accelerates the development and commercialization of medicines through its distinctive "Vant" model, a network of nimble, focused subsidiary companies such as Immunovant, Priovant, and Pulmovant.