GitHub - trynkaLab-admin/Treg_Multiomics: We generated a detailed resource of gene expression regulation in regulatory T cells (Tregs) and we integrated our data with immune disease variants. We identified QTL effects, performed colocalization with immune disease associated variants, overlapped immune disease GWAS signals with chromQTLs to functionally refined associated variants and used the prioritised genes to identify drug targets.

Branches Tags

Name		Name	Last commit message	Last commit date
Latest commit History 53 Commits
ATAC_Pipeline		ATAC_Pipeline
ChM_Pipeline		ChM_Pipeline
Colocalization		Colocalization
Example_Files		Example_Files
Genotype_Imputation		Genotype_Imputation
Multiomic_Integration_Table		Multiomic_Integration_Table
Plotting		Plotting
QC		QC
QTL_analysis		QTL_analysis
RNA_Pipeline		RNA_Pipeline
Variance_Decomposition		Variance_Decomposition

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We generated a detailed resource of gene expression regulation in regulatory T cells (Tregs) and we integrated our data with immune disease variants. We identified QTL effects, performed colocalization with immune disease associated variants, overlapped immune disease GWAS signals with chromQTLs to functionally refined associated variants and used…