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serafin-stats/README.md

Hi there 👋 I'm Casandra Serafin

Biostatistician and data scientist focused on statistical modeling, reproducible research, and applied health analytics.

Currently Working On 🔭

I’m currently working on reproducible statistical analysis pipelines for biomedical research, including mixed-effects modeling, simulation-based power analysis, and interpretable modeling of clinical and perceptual outcomes.

Research and Analysis Interests

  • Generalized Linear Models and Mixed Effects Models
  • Statistical Modeling for Biomedical Data
  • Causal Inference and Observational Study Design
  • Simulation-Based Power Analysis
  • Reproducible Data Science Workflows

🌱 I’m currently learning more about scalable statistical computing and best practices for production-ready data science workflows. Learning French too! 🇫🇷

👯 I’m looking to collaborate on applied statistical modeling projects in healthcare, clinical research, and real-world evidence.

Tools and Languages

R • Python • SQL • Git • Bash
tidyverse • lme4 • brms • scikit-learn • JAX

Selected Projects

Breast Implant Aesthetics Analysis

Statistical modeling of postoperative breast geometry and its association with aesthetic and naturalness ratings using mixed-effects ordinal and logistic regression models.

Simulation-Based Power Analysis

Development of simulation frameworks to evaluate statistical power under varying sample sizes, clustering structures, and missing data patterns.

RNA-seq Quality Control Pipeline

Implementation of reproducible workflows for bulk RNA-seq data quality assessment and downstream analysis.

Reproducible Research

Most projects in this repository use:

  • renv for environment reproducibility
  • Quarto / R Markdown for reports
  • Git for version control

Contact

LinkedIn: [https://www.linkedin.com/in/casandra-serafin/]

Popular repositories Loading

  1. advanced-statistical-computing advanced-statistical-computing Public

    This course is part of the USC Graduate Biostatistics Program and is designed for second-year and beyond students interested in designing and implementing computational inferential tools for research.

  2. breast-implant-ratio-analysis breast-implant-ratio-analysis Public

    Quantifying Aesthetic and Naturalness Outcomes from Post-Operative Breast Augmentation Images.

    R

  3. serafin-stats serafin-stats Public

  4. bayesian-adaptive-trial-igf1 bayesian-adaptive-trial-igf1 Public

    This project simulates a Bayesian adaptive Phase II clinical trial evaluating a hypothetical therapy that modulates circulating IGF-1 (insulin-like growth factor 1) in colorectal cancer patients. T…

    Jupyter Notebook