This R package library simplifies some calculations for the success of a clinical trial given data from some initial trial. The approach throughout is to produce a prior for effect size, use the initial trial data to produce a posterior distribution for effect size, and then simulate the later trial using this posterior. This is an intrinsically Bayesian approach.
# install.packages('devtools')
devtools::install_github("scientific-computing-solutions/assurance", build_vignettes = TRUE)Contact paul.metcalfe@astrazeneca.com or david.ruau@astrazeneca.com for further details.