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scConvexNMF: Single-cell Convex on Negative Matrix Factorization

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Overview

A generative model that decomposes single cell gene expression profiles into a set of gene programs, each of which representing a convex combination of tightly coexpressed genes.

Requirements

The following R packages are required:

Note, RcppEigen also needs gfortran to be installed on the system.

The code was tested using R 4.3.1 running on CentOS Linux 7.

scConvexNMF should be compatible with Windows, Mac, and Linux operating systems.

Installation

From an R session, type:

devtools::install_github("csglab/scConvexNMF")

Usage

Check the following notebooks for examples on how to run scConvexNMF:

Contact

We use GitHub issues for tracking requests and bugs. Please submit a new issue if you have any comment or you would like to report a software bug.

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Single cell convex non-negative matrix factorization

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