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fix: report No_mutability genes correctly and avoid UnboundLocalError #101

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Merged
St3451 merged 2 commits into from
May 27, 2026
Merged

fix: report No_mutability genes correctly and avoid UnboundLocalError #101

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3ac6c09
fix: optimize gene filtering for mutability status reporting
St3451 May 27, 2026
033c6a8
fix: update 'Mut_in_gene' assignment to use gene values directly
St3451 May 27, 2026
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7 changes: 4 additions & 3 deletions scripts/run/clustering.py
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Original file line number Diff line number Diff line change
Expand Up @@ -604,8 +604,9 @@ def run_clustering(input_path,
init_mutabilities_module(mutab_config)
seq_df = seq_df[seq_df["Reference_info"] == 1]
seq_df['Exons_coord'] = seq_df['Exons_coord'].apply(eval)
genes_to_process = [gene for gene in genes_to_process if gene in seq_df["Gene"].unique()]
genes_not_mutability = [gene for gene in genes_to_process if gene not in seq_df["Gene"].unique()]
genes_in_seq_df = set(seq_df["Gene"].unique())
genes_not_mutability = [gene for gene in genes_to_process if gene not in genes_in_seq_df]
genes_to_process = [gene for gene in genes_to_process if gene in genes_in_seq_df]
logger.debug("Computing probabilities..")
miss_prob_dict = get_miss_mut_prob_dict(mut_rate_dict=None, seq_df=seq_df,
mutability=True, mutability_config=mutab_config)
Expand All @@ -615,7 +616,7 @@ def run_clustering(input_path,
result_gene = pd.DataFrame({"Gene" : genes_not_mutability,
"Uniprot_ID" : np.nan,
"F" : np.nan,
"Mut_in_gene" : np.nan,
"Mut_in_gene" : genes.loc[genes_not_mutability].values,
"Ratio_not_in_structure" : np.nan,
"Ratio_WT_mismatch" : np.nan,
"Mut_zero_mut_prob" : np.nan,
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