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4 changes: 2 additions & 2 deletions DESCRIPTION
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Package: colocboost
Type: Package
Date: 2026-06-06
Date: 2026-06-07
Title: Multi-Context Colocalization Analysis for QTL and GWAS Studies
Version: 1.0.8
Version: 1.0.9
Authors@R: c(
person(given = "Xuewei", family = "Cao", email = "xc2270@cumc.columbia.edu", role = c("cre", "aut", "cph")),
person(given = "Haochen", family = "Sun", email = "hs3393@cumc.columbia.edu", role = c("aut", "cph")),
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45 changes: 29 additions & 16 deletions cran-comments.md
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## colocboost 1.0.8 release comments
## colocboost 1.0.9 release comments

This is an update to colocboost 1.0.7.
This is a CRAN-requested patch update to colocboost 1.0.8.

This release includes:
This patch includes:

* Added X_ref support as a memory-efficient alternative to precomputed LD matrices for summary-statistics workflows.
* Added and refined robust post-filtering for colocalization and trait-specific uncolocalized events.
* Improved computational efficiency for repeated matrix products in reference-panel workflows.
* Improved plotting robustness for extreme association signals and coefficient or z-score displays.
* Updated documentation and vignettes, including the bioinformatics pipeline vignette.
* Fixed the CRAN-reported macOS arm64 test issue in the uCoS robustness tests.
The tests now use a stronger simulation setting and aligned inputs for
`get_robust_ucos()` and `get_ucos_evidence()`, so they no longer depend on
weak or platform-sensitive simulated signals.

No R source code or package dependency changes were made for this CRAN-requested
patch.

## CRAN-requested macOS arm64 fix

CRAN reported test failures for colocboost 1.0.8 on macOS arm64 and requested a
correction before 2026-06-21. The failing test checked robust trait-specific
uncolocalized event filtering and evidence calculation. The issue has been
addressed by strengthening the simulation used in the test suite and by using
matched `cb_obj` and `cb_res` inputs for the evidence check.

CRAN also pointed to the M1mac check service for arm64 issues:
https://www.stats.ox.ac.uk/pub/bdr/M1mac/README.txt. CRAN noted that this
service runs a much older OS/toolchain and that toolchain differences often
matter. This submission therefore fixes the test design itself, rather than
relying on a platform-specific workaround.

## R CMD check results

Expand All @@ -24,11 +40,8 @@ This NOTE is expected. The installed size is mainly due to reduced example datas

## Previous comments

* This is an important update for the latest release colocboost_1.0.5. We resolved an computational issue caused by the latest update.
* This package implements methods described in our paper "ColocBoost" (Cao et al., 2025), added in DESCRIPTION
* Fixed issues requested by CRAN in previous submission:
- Reduced tarball less than 5 MB
- Fixed reset users' options issues
- Added proper COPYRIGHT HOLDER and ORGANIZATION to LICENSE
- Added explanation of acronyms used in this package to inst/WORDLIST
* The examples and vignettes use small datasets to avoid long check times
* This package implements methods described in our paper "ColocBoost"
(Cao et al., 2025), now cited in DESCRIPTION.
* Previous CRAN-requested fixes addressed tarball size, user option handling,
LICENSE metadata, and accepted package/domain terms in inst/WORDLIST.
* The examples and vignettes use small datasets to avoid long check times.
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