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BioML

Group name PerezLab_Gators

Overview

Here we document how we used RFDiffusion, ProteinMPNN, and AF2 to generate de novo binders for the extracellular domain of CD20.

Abbreviations

RT Rituximab (6VJA)

OF Ofatumumab (6Y92)

OB Obinutuzumab (6Y97)

DN De Novo

Timeline

August 24, 2024 Kick-off event and official start of the challenge.

September 6, 2024 Deadline for antibody-based designs.

September 20, 2024 Deadline for 2nd generation designs.

September 30, 2024 Submission deadline.

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