Open infrastructure to accelerate cures for children with cancer.
LittleCures is a public, open-source effort to build shared tools, data, and models for pediatric oncology — starting with the deadliest and most neglected diseases.
- Most cancer drugs are developed for adults; children are an afterthought.
- The deadliest pediatric brain cancers, like DIPG/DMG, have seen almost no survival improvement in decades.
- Data is siloed across institutions, making rare pediatric cancers impossible to model at scale.
- Access is wildly unequal: survival can be 80% in high-income countries and below 20% in low-income countries for the same disease.
We do not accept that a child's life is worth less because the market is small.
- Open pediatric trial matching — help oncologists and families find relevant clinical trials fast.
- Open target and IP registry — map molecular drivers, patent status, trials, and models for neglected pediatric cancers.
- Federated learning tools — train shared models without moving patient data.
- Access and advocacy infrastructure — open IP, equitable licensing, and policy tools.
- Vite + React + TypeScript
- Tailwind CSS
- Lucide icons
- Vitest for testing
pnpm install
pnpm devpnpm build
pnpm previewpnpm testThe live site is at https://littlecures.org/ and is hosted on GitHub Pages. Pushes to main trigger the .github/workflows/deploy.yml action, which builds and deploys automatically.
You can also run pnpm build and serve the dist/ directory on any static host.
See CONTRIBUTING.md. We welcome engineers, designers, clinicians, researchers, and advocates.