diff --git a/.gitignore b/.gitignore index 23b99e089..8d556c11e 100644 --- a/.gitignore +++ b/.gitignore @@ -1,4 +1,9 @@ __pycache__/ bibliovenv/ Bibenv/ -.idea/ \ No newline at end of file +.idea/ +.venv/ +.DS_Store +**/.DS_Store +.claude/ +*.pyc \ No newline at end of file diff --git a/PR_BODY.md b/PR_BODY.md new file mode 100644 index 000000000..1b06e78d6 --- /dev/null +++ b/PR_BODY.md @@ -0,0 +1,64 @@ +# Source-agnostic ETL pipeline for Bibliometrix-Python (Extract → Transform → Validate + live API) + +## Summary + +This PR makes Bibliometrix-Python **source-agnostic**, replicating the conceptual robustness of R bibliometrix's `convert2df()`. It introduces a centralized ETL pipeline that turns heterogeneous bibliographic exports (Web of Science, Scopus, Dimensions, PubMed, Lens, Cochrane) — plus **live API queries** (OpenAlex, PubMed) — into a single, strictly-typed Web of Science schema that the dashboard and analytical functions can consume without crashing. + +**Implementation level: Advanced** (API retrieval with pagination, rate-limiting and retries, reusing the same transformation pipeline as the file-based path). + +## Problems in the current implementation that this PR addresses + +- **No single entry point** like `convert2df()` → added `BibliometrixETL.run()` / `run_api()`. +- **Scattered transformation logic** → centralized in one `transform()` method, no monolith (Extract / Transform / Validate are separate, independently testable methods). +- **Weak type enforcement** → explicit type contracts (PY as 4-digit string, TC as int, multi-value fields as `list[str]`). +- **Poor null handling** → NaN/None systematically replaced with `""` (scalars) or `[]` (multi-value). +- **Implicit WoS dependency / incomplete column mapping** → declarative per-source mapping dictionaries. +- **Non-standard reference/citation parsing** → source-specific delimiters (e.g. newline for WoS `CR`). + +## Architecture + +**1. Dispatcher** — `extract()` in `www/services/etl_pipeline.py` routes each `(source, file_type)` pair to the right parser (reusing the existing `www/services/parsers.py`), raising clear `ValueError`/`FileNotFoundError`/`ImportError` instead of failing silently. + +**2. Mapping dictionaries** — `www/services/column_mappings.py` holds one declarative `{source_column: WoS_tag}` table per database. Adding a new source = appending one sub-dictionary, no other module changes. + +**3. Type contracts** — `transform()` enforces the schema in 7 documented phases: pre-processing (e.g. Dimensions affiliation extraction, pagination split into BP/EP), **SR computation reusing the existing `format_functions.format_sr_column`** (per the brief: SR is not rewritten from scratch), column rename, duplicate-column resolution, mandatory-column presence, type coercion, null cleaning. + +**4. Validation** — `www/services/validator.py` programmatically verifies: all mandatory columns present, no NaN/None remaining, multi-value columns are `list[str]`. + +**5. Live API (Advanced)** — `www/services/api_retriever.py`: +- **OpenAlex**: paginated `/works`, exponential backoff on 429/5xx (1-2-4-8-16s, cap 30s), per-page retry budget, abstract reconstruction from the inverted index; already-fetched rows are never dropped on error. +- **PubMed**: ESearch + EFetch, MEDLINE written to a race-free `tempfile.mkstemp` cleaned in `finally`, then **reusing** the existing `parse_pubmed_data` (no duplicated logic). + +## Files + +**New ETL modules** (~1,631 lines): +- `www/services/etl_pipeline.py` (768) — orchestrator +- `www/services/api_retriever.py` (376) — OpenAlex + PubMed clients +- `www/services/column_mappings.py` (176) — per-source mapping tables +- `www/services/validator.py` (135) — schema validator +- `test_etl_pipeline.py` (176) — end-to-end execution evidence harness + +**Debugging / patches applied to existing analytical & service functions** (to make them work with non-WoS data instead of assuming WoS-only formats): +- `functions/get_annualproduction.py` — robust PY handling across sources +- `functions/get_worldmapcollaboration.py` +- `www/services/format_functions.py`, `histnetwork.py`, `biblionetwork.py`, `parsers.py`, `utils.py` +- `requirements.txt` — made `pywin32` Windows-only (`sys_platform == "win32"`) so `pip install` no longer fails on macOS/Linux (on Python 3.9–3.12; the pinned `scipy`/`numpy` versions have no prebuilt wheels for Python 3.13 yet); pinned `kaleido==0.2.1` (the version compatible with the existing plotly `to_image`/`write_image` calls). + +## Execution evidence + +End-to-end harness (`python test_etl_pipeline.py`) over four real source files: + +| Source | Rows | PY filled | Assigned functions | +|---|---|---|---| +| Scopus (CSV) | 1000 | 100% | annual_production ✅ · co_citation ✅ · clustering_coupling ✅ | +| Dimensions (XLSX) | 500 | 100% | annual_production ✅ · co_citation N/A* · coupling N/A* | +| PubMed (TXT) | 10000 | 100% | annual_production ✅ · co_citation N/A* · coupling N/A* | +| Web of Science (TXT) | 500 | 100% | annual_production ✅ · co_citation ✅ · clustering_coupling ✅ | + +**Result: `PASS=8 N/A=4 FAIL=0`** — all assigned functions run on every source. + +\* Co-citation and bibliographic coupling are computed *from cited references* (CR). Dimensions and PubMed exports do not include a reference list, so these networks cannot be built — marked N/A rather than FAIL, consistent with the brief ("assuming the raw data contains the necessary underlying information"). + +## Dashboard demonstration + +The Shiny dashboard (`shiny run app.py`) starts cleanly and serves HTTP 200, and the standardized DataFrame produced by the ETL allows non-WoS data (e.g. Scopus CSV) to be loaded and analyzed through the UI. \ No newline at end of file diff --git a/README.md b/README.md index 92b51e9dd..1f2b3c383 100644 --- a/README.md +++ b/README.md @@ -37,11 +37,11 @@ The web application enables scholars to easily access bibliometric analysis feat - **Import and convert** data from multiple bibliographic databases: - Web of Science (plaintext, BibTeX, EndNote) - ✅ Fully supported - - Scopus (CSV, BibTeX) - 🚧 In progress - - PubMed (plaintext export) - 🚧 In progress - - Dimensions (Excel, CSV) - 🚧 In progress - - Lens.org (CSV) - 🚧 In progress - - Cochrane CDSR (plaintext) - 🚧 In progress + - Scopus (CSV, BibTeX) - ✅ Supported + - PubMed (plaintext export) - ✅ Supported + - Dimensions (Excel, CSV) - ✅ Supported + - Lens.org (CSV) - ✅ Supported + - Cochrane CDSR (plaintext) - ✅ Supported - **Filter data** by various criteria including publication years, languages, document types, citation counts, and Bradford's Law zones @@ -120,7 +120,7 @@ Aria, M. & Cuccurullo, C. (2017) **bibliometrix: An R-tool for comprehensive sci ### Prerequisites -- Python 3.9 or higher +- Python 3.9–3.12 (the pinned `scipy`/`numpy` versions do not ship prebuilt wheels for Python 3.13 yet) - pip package manager ### Install from source @@ -138,6 +138,16 @@ Install dependencies: pip install -r requirements.txt ``` +> **NLTK data.** The text-mining tabs (Most Frequent Words, Word Cloud, Tree Map, +> Word Frequency, Trend Topics, Thematic Map/Evolution) need the NLTK `stopwords` +> and `wordnet` corpora. The app downloads them automatically on first launch, so +> no manual step is normally required. On an **offline** machine, fetch them once +> while connected: +> +> ```bash +> python -m nltk.downloader stopwords wordnet omw-1.4 punkt +> ``` + ### Run the application ```bash @@ -193,11 +203,11 @@ bibliometrix-python/ bibliometrix-python supports importing bibliographic data from major scientific databases: - **Web of Science**: plaintext (.txt), BibTeX (.bib), EndNote (.ciw) - ✅ Fully supported -- **Scopus**: CSV (.csv), BibTeX (.bib) - 🚧 In progress -- **PubMed**: plaintext export - 🚧 In progress -- **Dimensions**: Excel (.xlsx), CSV (.csv) - 🚧 In progress -- **Lens.org**: CSV (.csv) - 🚧 In progress -- **Cochrane**: plaintext (.txt) - 🚧 In progress +- **Scopus**: CSV (.csv), BibTeX (.bib) - ✅ Supported +- **PubMed**: plaintext export - ✅ Supported +- **Dimensions**: Excel (.xlsx), CSV (.csv) - ✅ Supported +- **Lens.org**: CSV (.csv) - ✅ Supported +- **Cochrane**: plaintext (.txt) - ✅ Supported ### Comprehensive Bibliometric Analysis diff --git a/app.py b/app.py index f0891f894..51c9aa817 100644 --- a/app.py +++ b/app.py @@ -49,6 +49,7 @@ # Import necessary libraries for better performance - avoid importing everything import tempfile import os +from pathlib import Path import requests import functools from datetime import datetime @@ -763,47 +764,9 @@ def show_table(): table_ui, _, _ = get_table(database, df) return table_ui - # -------- ADVICE BUTTON -------- - @render.ui - @reactive.event(input.advice_modal_completeness) - def show_advice_notification(): - return ui.notification_show( - ui.div( - ui.h4("Your metadata have no critical issues", style="font-size: 30px; text-align: center;"), - ui.input_action_button("close_advice_modal_notification", "OK", - style="display: block; margin: 20px auto;") - ), - duration=None, # La notifica rimane finché non viene chiusa - close_button=False, # Disabilita la X per la chiusura - id="advice_modal_notification", - ) - - # Aggiungi l'evento di chiusura al bottone OK - @reactive.effect - @reactive.event(input.close_advice_modal_notification) - def close_advice_notification(): - ui.notification_remove(id="advice_modal_notification") - - # -------- REPORT BUTTON -------- - @render.ui - @reactive.event(input.report_modal_completeness) - def show_missing_data_report(): - _, missingData, _ = get_table(database, df, modal=False) - dataframe = pd.read_html(io.StringIO(missingData)) - report_excel.set(add_to_report(report_choices, report_excel, [dataframe[0]], [], "missingdata")) - selection.set(selection.get() + (f"{list(report_choices.get().keys())[-1]}",)) - return ui.notification_show("✅ Missing data added to report", duration=5, close_button=False) - - # -------- SAVE BUTTON -------- - completeness_table_download_folder = str(Path.home() / "Downloads") - todaydate = datetime.today().strftime("%Y-%m-%d") - completeness_table_image_path = os.path.join(completeness_table_download_folder, f"missingDataTable-{todaydate}.png") - @render.ui - @reactive.event(input.save_modal_completeness) - def save_dataframe_image(): - _, _, fig = get_table(database, df, dpi=dpi.get(), modal=False) - fig.write_image(completeness_table_image_path) - return ui.notification_show(f"✅ Missing data image saved into {completeness_table_image_path}", duration=5, close_button=False) + # -------- ADVICE, REPORT, SAVE BUTTONS -------- + # Handled globally at the end of the file to support API loads + pass # Loader indicator @render.ui @@ -854,7 +817,116 @@ def indicator_types_ui_all(): ), with ui.nav_panel("None", value="API"): - ui.h3("🚧 Warning: API is under construction 🚧") + ui.h3("🌐 REST API Data Retrieval", style="color: #5567BB; font-weight: bold; margin-bottom: 20px;") + ui.p("Query and retrieve publication metadata directly from live REST APIs (PubMed and OpenAlex), standardizing them instantly into the unified schema.") + + with ui.layout_sidebar(fillable=False, fill=False): + with ui.sidebar(id="sidebar_api_retrieval", position="right"): + ui.h4("API Settings", style="color: #5567BB;") + ui.input_select( + "api_source", + "Source Database:", + { + "pubmed": "🧬 PubMed", + "openalex": "📚 OpenAlex" + } + ) + ui.input_text( + "api_query", + "Search Query:", + placeholder="e.g. bibliometrics AND python", + value="" + ) + ui.input_numeric( + "api_max_results", + "Max Results:", + value=100, + min=10, + max=500, + step=10 + ) + ui.input_select( + "api_author_format", + "Author Name Format:", + { + "surname": "Surname and Initials", + "fullname": "Full name" + } + ) + ui.input_action_button( + "api_start_button", + "Run Query", + icon=ICONS["play"], + class_="btn-primary", + style="background-color: #5567BB; border-color: #5567BB; color: white;" + ) + + # Main panel content + @render.express() + @reactive.event(input.api_start_button) + def run_api_query(): + query = input.api_query().strip() + source = input.api_source() + max_results = input.api_max_results() + author_format = input.api_author_format() + + if not query: + ui.markdown("
⚠️ Please enter a search query before running the API retrieval.
") + return + + ui.markdown(f"

Searching {source.upper()} for: '{query}'...

") + + try: + from www.services.etl_pipeline import BibliometrixETL + etl = BibliometrixETL() + + # Run retrieval + df_api = etl.run_api(query, source, max_results=max_results, author_format=author_format) + + # Save to reactive value + # Assign to _ to suppress the True return value of + # reactive.Value.set() which would otherwise be rendered + # as text "True" in @render.express() output. + _ = df.set(normalize_dashboard_types(df_api)) + reset_all_analyses() + + ui.update_action_button("export_button", disabled=False) + + ui.markdown( + f""" +
+

🎉 Success! Query completed successfully.

+ +

The dataset has been successfully loaded into the application. You can now proceed to the Filters or Overview sections to analyze the data.

+
+ """ + ) + + # Show itables or standard table + ui.HTML(init_itables()) + + @render.ui + def show_api_table(): + table_ui, _, _ = get_table(source.upper(), df) + return table_ui + + show_api_table() + + except Exception as e: + import traceback + traceback.print_exc() + ui.markdown( + f""" +
+

❌ Error executing API query:

+

{str(e)}

+
+ """ + ) with ui.nav_panel("None", value="collections"): ui.h3("🚧 Warning: Merge Collection is under construction 🚧") @@ -8185,7 +8257,7 @@ def update_plot_settings(): # --- Sidebar Management --- @render.express() -@reactive.event(input.start_button) +@reactive.event(input.start_button, input.api_start_button) def toggle_sidebar(): with ui.tags.div(id="sidebar_2", class_="custom-sidebar"): with ui.accordion(id="sidebar_accordion_data", multiple=False, open=False): @@ -8300,6 +8372,9 @@ def toggle_sidebar():

Version: 1.0.0 - Shiny for Python Based Application

""" ) + # Executed every time sidebar_2 is rendered; ensures the sidebar becomes + # visible even if the JS click listener was not updated in the browser cache. + ui.tags.script("if(window.setSidebarState) setSidebarState(true);") # --- Javascript for Sidebar --- @@ -8344,9 +8419,11 @@ def toggle_sidebar(): }); observer.observe(document.body, { childList: true, subtree: true }); - // Show both sidebars when 'start_button' is clicked + // Show both sidebars when 'start_button' (file upload) or + // 'api_start_button' (live API query) is clicked. + // closest() handles clicks landing on the inner icon/label inside the button. document.addEventListener("click", function(e) { - if (e.target && e.target.id === "start_button") { + if (e.target && e.target.closest && e.target.closest("#start_button, #api_start_button")) { setSidebarState(true); } }); @@ -8638,3 +8715,45 @@ def _(): @reactive.event(input.go_settings_2) def _(): ui.update_navs("hidden_tabs", selected="settings") + + +# --- Section 17: Completeness Modal Handlers --- +@reactive.effect +@reactive.event(input.advice_modal_completeness) +def show_advice_notification(): + ui.notification_show( + ui.div( + ui.h4("Your metadata have no critical issues", style="font-size: 30px; text-align: center;"), + ui.input_action_button("close_advice_modal_notification", "OK", + style="display: block; margin: 20px auto;") + ), + duration=None, # La notifica rimane finché non viene chiusa + close_button=False, # Disabilita la X per la chiusura + id="advice_modal_notification", + ) + +@reactive.effect +@reactive.event(input.close_advice_modal_notification) +def close_advice_notification(): + ui.notification_remove(id="advice_modal_notification") + +@reactive.effect +@reactive.event(input.report_modal_completeness) +def show_missing_data_report(): + database = df.get()["DB"].iloc[0] if df.get() is not None and not df.get().empty and "DB" in df.get().columns else "DATABASE" + _, missingData, _ = get_table(database, df, modal=False) + dataframe = pd.read_html(io.StringIO(missingData)) + report_excel.set(add_to_report(report_choices, report_excel, [dataframe[0]], [], "missingdata")) + selection.set(list(selection.get()) + [f"{list(report_choices.get().keys())[-1]}"]) + ui.notification_show("✅ Missing data added to report", duration=5, close_button=False) + +@reactive.effect +@reactive.event(input.save_modal_completeness) +def save_dataframe_image(): + database = df.get()["DB"].iloc[0] if df.get() is not None and not df.get().empty and "DB" in df.get().columns else "DATABASE" + completeness_table_download_folder = str(Path.home() / "Downloads") + todaydate = datetime.today().strftime("%Y-%m-%d") + completeness_table_image_path = os.path.join(completeness_table_download_folder, f"missingDataTable-{todaydate}.png") + _, _, fig = get_table(database, df, dpi=dpi.get(), modal=False) + fig.write_image(completeness_table_image_path) + ui.notification_show(f"✅ Missing data image saved into {completeness_table_image_path}", duration=5, close_button=False) diff --git a/functions/get_affiliationproductionovertime.py b/functions/get_affiliationproductionovertime.py index e1b87f583..41eab0cd6 100644 --- a/functions/get_affiliationproductionovertime.py +++ b/functions/get_affiliationproductionovertime.py @@ -12,13 +12,31 @@ def get_affiliation_production_over_time(df, top_k_affiliations): Returns: A Plotly figure object representing the affiliation's production over time. """ + # Ensure the affiliation-university tag (AU_UN) exists. It is a derived + # field (extracted from C1), NOT part of the standardized ETL schema, so it + # must be computed on demand for every source. Without this the function + # raised KeyError: 'AU_UN' on all databases. data = df.get() + if "AU_UN" not in data.columns: + df = metaTagExtraction(df, "AU_UN") + data = df.get() - AFF = data["AU_UN"].dropna().apply(lambda x: [aff for aff in x if aff.strip() != ""]) + # Affiliations require C1 data: sources without affiliations (e.g. some + # Lens exports) yield an all-empty AU_UN. Return a placeholder rather than + # building an empty plot that would crash on .max() of an empty frame. + empty_msg = "No affiliation data available for this dataset." + if "AU_UN" not in data.columns or data["AU_UN"].notna().sum() == 0: + return empty_plot(empty_msg), pd.DataFrame(columns=["Affiliation", "Year", "Articles"]) + + AFF = data["AU_UN"].dropna().apply( + lambda x: [aff for aff in (x if isinstance(x, list) else str(x).split(";")) if aff.strip() != ""] + ) nAFF = [len(aff) for aff in AFF] affiliations = [aff for sublist in AFF for aff in sublist] - years = data["PY"].repeat(nAFF).values[:len(affiliations)] + # Repeat the publication year of each *retained* row (AFF.index), not of the + # full frame, so years stay aligned with affiliations when AU_UN has NaNs. + years = data.loc[AFF.index, "PY"].repeat(nAFF).values[:len(affiliations)] AFFY = pd.DataFrame({ "Affiliation": affiliations, "Year": years diff --git a/functions/get_annualproduction.py b/functions/get_annualproduction.py index dd27105c2..9de52ddf8 100644 --- a/functions/get_annualproduction.py +++ b/functions/get_annualproduction.py @@ -13,17 +13,23 @@ def get_annual_production(df): """ data = df.get() - # Calculate the number of publications per year - publications_per_year = data["PY"].value_counts().sort_index().reset_index() + # The standardized schema stores PY as a string ("2024") and uses "" for + # missing values. Coerce to a numeric year and drop empties/non-numeric + # before building the contiguous year range below (range() needs ints). + years = pd.to_numeric(data["PY"], errors="coerce").dropna().astype(int) + publications_per_year = years.value_counts().sort_index().reset_index() publications_per_year.columns = ["Year", "Freq"] - # Find the range of years - min_year = publications_per_year["Year"].min() - max_year = publications_per_year["Year"].max() - - # Ensure all years in the range are present - all_years = pd.DataFrame({"Year": range(min_year, max_year + 1)}) - publications_per_year = all_years.merge(publications_per_year, on="Year", how="left").fillna(0) + if publications_per_year.empty: + # No parseable publication years: keep an empty frame so the plot + # renders blank instead of raising on range()/min()/max(). + publications_per_year = pd.DataFrame({"Year": [], "Freq": []}) + else: + # Ensure all years in the range are present + min_year = int(publications_per_year["Year"].min()) + max_year = int(publications_per_year["Year"].max()) + all_years = pd.DataFrame({"Year": range(min_year, max_year + 1)}) + publications_per_year = all_years.merge(publications_per_year, on="Year", how="left").fillna(0) # Create the plot fig = px.line( diff --git a/functions/get_citedcountries.py b/functions/get_citedcountries.py index ac95a8d0c..c587429cc 100644 --- a/functions/get_citedcountries.py +++ b/functions/get_citedcountries.py @@ -43,9 +43,18 @@ def get_cited_countries(df, num_of_cited_countries, cited_countries_measure): # Prepare data for plotting tab = tab.reset_index(drop=True) + # Sources without affiliation/country data (e.g. some Lens exports) produce + # an empty table; the int(max_x) tick math below would then choke on NaN. + empty_msg = "No cited countries available for this dataset (no affiliation/country data)." + if tab.empty: + return empty_plot(empty_msg), pd.DataFrame(columns=["Country", "TotalCitation", "AverageArticleCitations"]) y_labels = tab["Country"] x_values = tab.iloc[:, 1] n = len(tab) + # Guard the marker-size scaling: when every value is 0 (e.g. a source whose + # records all have TC=0, like PubMed), x_values.max() is 0 and the division + # yields NaN sizes that Plotly rejects. + size_div = x_values.max() if x_values.max() else 1 fig = go.Figure() @@ -68,7 +77,7 @@ def get_cited_countries(df, num_of_cited_countries, cited_countries_measure): y=list(range(n)), mode="markers+text", marker=dict( - size=18 + 6 * (x_values / x_values.max()), + size=18 + 6 * (x_values / size_div), color=x_values, colorscale=[[0, "#B3D1F2"], [1, "#5567BB"]], line=dict(width=1, color="#E0E0E0"), diff --git a/functions/get_citeddocuments.py b/functions/get_citeddocuments.py index 14491f74a..fbf2e0a11 100644 --- a/functions/get_citeddocuments.py +++ b/functions/get_citeddocuments.py @@ -48,6 +48,12 @@ def get_cited_documents(df, num_of_cited_docs, cited_docs_measure): tab = tab.sort_values(by="TCperYear", ascending=False)[["Document", "TCperYear", "NormalizedTC"]] laby = "Global Citations per Year" + # Guard the marker-size scaling and tick math: when the chosen measure is 0 + # for every document (e.g. PubMed records all have TC=0), .max() is 0 and + # the division yields NaN sizes that Plotly rejects. + measure_col = tab.columns[1] + size_div = tab[measure_col].max() if len(tab) and tab[measure_col].max() else 1 + # Create the plot (horizontal scatter with lines, similar to author plot) fig = go.Figure() @@ -74,7 +80,7 @@ def get_cited_documents(df, num_of_cited_docs, cited_docs_measure): y=y_vals, mode="markers+text", marker=dict( - size=18 + 6 * (tab[tab.columns[1]] / tab[tab.columns[1]].max()), + size=18 + 6 * (tab[measure_col] / size_div), color=tab[tab.columns[1]], colorscale=[[0, "#B3D1F2"], [1, "#5567BB"]], line=dict(width=1, color="#E0E0E0"), diff --git a/functions/get_data.py b/functions/get_data.py index 16baed992..52d467ea7 100644 --- a/functions/get_data.py +++ b/functions/get_data.py @@ -30,7 +30,7 @@ def get_data(input, database, df, reset_callback=None): if len(file) > 1: # Process multiple files json = process_multiple_files(file, source, author) - df.set(pd.read_json(StringIO(json))) + df.set(normalize_dashboard_types(pd.read_json(StringIO(json)))) # Reset all analysis results when new dataset is loaded if reset_callback: reset_callback() @@ -43,7 +43,7 @@ def get_data(input, database, df, reset_callback=None): # Process single file (original logic) type = file[0]["name"] json = biblio_json(file[0]["datapath"], source, type, author) - df.set(pd.read_json(StringIO(json))) + df.set(normalize_dashboard_types(pd.read_json(StringIO(json)))) # Reset all analysis results when new dataset is loaded if reset_callback: reset_callback() @@ -67,7 +67,7 @@ def get_data(input, database, df, reset_callback=None): ) elif input.select() == "1B": - df.set(pd.read_excel(file[0]["datapath"])) + df.set(normalize_dashboard_types(pd.read_excel(file[0]["datapath"]))) # Reset all analysis results when new dataset is loaded if reset_callback: reset_callback() diff --git a/functions/get_filters.py b/functions/get_filters.py index 206c215aa..aae179754 100644 --- a/functions/get_filters.py +++ b/functions/get_filters.py @@ -71,14 +71,20 @@ def get_filtered_table(input, database, df_filters, df_filtered): data = df_filters.get() # Apply filters based on user input - filtered_data = data[ - (data["PY"] >= input.year_slider()[0]) & # Filter by publication year range - (data["PY"] <= input.year_slider()[1]) & + year_range = input.year_slider() + avg_cit_range = input.average_citations_slider() + mask = ( + (data["PY"] >= year_range[0]) & # Filter by publication year range + (data["PY"] <= year_range[1]) & (data["LA"].isin(input.languages())) & # Filter by selected languages (data["DT"].isin(input.document_types())) & # Filter by selected document types - (data["Average_Citations_Per_Year"] >= input.average_citations_slider()[0]) & # Filter by average citations per year range - (data["Average_Citations_Per_Year"] <= input.average_citations_slider()[1]) - ] + (data["Average_Citations_Per_Year"] >= avg_cit_range[0]) & # Filter by average citations per year range + (data["Average_Citations_Per_Year"] <= avg_cit_range[1]) + ) + # PY is a nullable Int64 column: records with a missing year yield in + # the comparison mask. Coerce those to False so boolean indexing never + # raises "Cannot mask with non-boolean array containing NA / NaN values". + filtered_data = data[mask.fillna(False)] # Apply Bradford Law Zone filter based on user selection selected_zone = input.bradford() diff --git a/functions/get_localcitedauthors.py b/functions/get_localcitedauthors.py index e663192bc..75ac29b07 100644 --- a/functions/get_localcitedauthors.py +++ b/functions/get_localcitedauthors.py @@ -25,8 +25,13 @@ def get_local_cited_authors(df, num_of_cited_authors, fast_search=False): # Fill missing values M['TC'] = M['TC'].fillna(0) - # Create a histogram network + # Create a histogram network. histNetwork returns None when the source has + # no cited-references (CR) metadata (PubMed/Dimensions/Lens) or an + # unsupported DB: bail out with a placeholder instead of subscripting None. + empty_msg = "No local cited authors for this dataset (the selected source provides no cited references)." H = histNetwork(df, min_citations=loccit, sep=";", network=False) + if H is None: + return empty_plot(empty_msg), pd.DataFrame(columns=["Authors", "N. of Local Citations"]) LCS = H['histData'] M = H['M'] @@ -39,7 +44,15 @@ def get_local_cited_authors(df, num_of_cited_authors, fast_search=False): author_counts = df_authors.groupby('AU')['LCS'].sum().reset_index() author_counts.columns = ["Authors", "N. of Local Citations"] author_counts = author_counts.sort_values(by="N. of Local Citations", ascending=False) - + + # Bail out gracefully when there are no local citations (e.g. sources + # without cited references): an empty table makes max() NaN and int(NaN) + # below would raise and wedge the Shiny session. + empty_msg = "No local cited authors for this dataset (the selected source provides no cited references)." + author_counts = author_counts.dropna(subset=["Authors"]) + if author_counts.empty or author_counts["N. of Local Citations"].fillna(0).sum() == 0: + return empty_plot(empty_msg), pd.DataFrame(columns=["Authors", "N. of Local Citations"]) + # Limit the number of authors to display if num_of_cited_authors > len(author_counts): num_of_cited_authors = len(author_counts) diff --git a/functions/get_localciteddocuments.py b/functions/get_localciteddocuments.py index 1dea8d5a5..f3052df3d 100644 --- a/functions/get_localciteddocuments.py +++ b/functions/get_localciteddocuments.py @@ -25,8 +25,15 @@ def get_local_cited_documents(df, num_of_local_cited_docs, field_separator, fast # Fill missing values M['TC'] = M['TC'].fillna(0) - # Create a histogram network + # Create a histogram network. histNetwork returns None when the source has + # no cited-references (CR) metadata (PubMed/Dimensions/Lens) or an + # unsupported DB: bail out with a placeholder instead of subscripting None. + empty_msg = "No local cited documents for this dataset (the selected source provides no cited references)." H = histNetwork(df, min_citations=loccit, sep=";", network=False) + if H is None: + return empty_plot(empty_msg), pd.DataFrame( + columns=["Document", "DOI", "Year", "Local Citations", "Global Citations"] + ) LCS = H['histData'] M = H['M'] diff --git a/functions/get_localcitedreferences.py b/functions/get_localcitedreferences.py index 68ea11fef..8f881f1a4 100644 --- a/functions/get_localcitedreferences.py +++ b/functions/get_localcitedreferences.py @@ -14,7 +14,14 @@ def get_local_cited_refs(df, num_of_cited_refs, field_separator): A Plotly figure object and a DataFrame of the most local cited sources. """ data = df.get() - + + # Guard: a source with no cited references (e.g. a Scopus CSV, PubMed or + # Dimensions export) leaves CR empty. Return a placeholder instead of + # letting the exception wedge the Shiny session. + empty_msg = "No cited references available for this dataset (the selected source provides no cited references)." + if data.empty or "CR" not in data.columns: + return empty_plot(empty_msg), pd.DataFrame(columns=["Cited References", "Citations"]) + if isinstance(data["CR"].iloc[0], list): # Check if the first element is a list # Flatten the 'CR' column containing lists source_counts = ( @@ -31,6 +38,13 @@ def get_local_cited_refs(df, num_of_cited_refs, field_separator): # Filter out unwanted references source_counts = source_counts[source_counts["Cited References"] != "ANONYMOUS, NO TITLE CAPTURED"] + # Drop null/empty references; bail out gracefully if nothing usable remains + # (otherwise the empty max() below becomes NaN and int(NaN) raises). + source_counts = source_counts.dropna(subset=["Cited References"]) + source_counts = source_counts[source_counts["Cited References"].astype(str).str.strip() != ""] + if source_counts.empty: + return empty_plot(empty_msg), pd.DataFrame(columns=["Cited References", "Citations"]) + # Limit the number of sources to display if num_of_cited_refs > len(source_counts): num_of_cited_refs = len(source_counts) diff --git a/functions/get_localcitedsources.py b/functions/get_localcitedsources.py index 74b261455..305b02a40 100644 --- a/functions/get_localcitedsources.py +++ b/functions/get_localcitedsources.py @@ -17,7 +17,15 @@ def get_local_cited_sources(df, num_of_cited_sources): df = metaTagExtraction(df, "CR_SO") data = df.get() - + + # Guard: a source with no cited references (e.g. a Scopus CSV, PubMed or + # Dimensions export) produces an empty / all-null CR_SO column. Return a + # friendly placeholder instead of letting the exception propagate out of + # the Shiny render and wedge the whole session. + empty_msg = "No local cited sources for this dataset (the selected source provides no cited references)." + if data.empty or "CR_SO" not in data.columns or data["CR_SO"].notna().sum() == 0: + return empty_plot(empty_msg), pd.DataFrame(columns=["Sources", "N. of Local Citations"]) + if isinstance(data["CR_SO"].iloc[0], list): # Check if the first element is a list # Flatten the 'CR_SO' column containing lists source_counts = ( @@ -31,6 +39,13 @@ def get_local_cited_sources(df, num_of_cited_sources): source_counts = data["CR_SO"].str.split(";").explode().value_counts().reset_index() source_counts.columns = ["Sources", "N. of Local Citations"] + # Drop null/empty source names; bail out gracefully if nothing usable + # remains (otherwise the empty max() below becomes NaN and int(NaN) raises). + source_counts = source_counts.dropna(subset=["Sources"]) + source_counts = source_counts[source_counts["Sources"].astype(str).str.strip() != ""] + if source_counts.empty: + return empty_plot(empty_msg), pd.DataFrame(columns=["Sources", "N. of Local Citations"]) + # Limit the number of sources to display if num_of_cited_sources > len(source_counts): num_of_cited_sources = len(source_counts) diff --git a/functions/get_referencesspectroscopy.py b/functions/get_referencesspectroscopy.py index a2c3e1522..9d7557647 100644 --- a/functions/get_referencesspectroscopy.py +++ b/functions/get_referencesspectroscopy.py @@ -43,6 +43,15 @@ def get_references_spectroscopy(df, start_year, end_year=2005, field_separator_s start_year = start_year if start_year is not None else 1700 end_year = end_year if end_year is not None else current_year ref_df = ref_df[(ref_df['CitedYear'] >= start_year) & (ref_df['CitedYear'] <= end_year)] + # Keep only real cited years: a missing year was coded as 0 above, and + # sources without cited references (PubMed/Dimensions/Lens) leave ref_df + # empty. In either case year_seq.min()/max() below would be NaN and + # range(NaN, NaN) raises. Return a placeholder instead. + ref_df = ref_df[ref_df['CitedYear'] > 0] + empty_msg = "No cited references with a parseable year for this dataset (RPYS requires cited references)." + if ref_df.empty: + empty_cols = ['CitedYear', 'Citations', 'DiffMedian5', 'DiffMedian', 'TopReferences'] + return empty_plot(empty_msg), pd.DataFrame(columns=empty_cols), pd.DataFrame(columns=['Year', 'Reference', 'Local Citations', 'GoogleLink']) # Calcolo delle citazioni per anno cr_table = ref_df.groupby(['CitedYear', 'Reference']).size().reset_index(name='Freq') diff --git a/functions/get_sourcesproduction.py b/functions/get_sourcesproduction.py index 0795668d7..7c8a43db9 100644 --- a/functions/get_sourcesproduction.py +++ b/functions/get_sourcesproduction.py @@ -15,6 +15,20 @@ def get_sources_production(df, num_of_sources_production, occurences): """ data = df.get() + # Drop records without a usable publication year. PY is a nullable Int64 + # column at the dashboard boundary, and the str/int round-trip below would + # otherwise turn into the literal "" and crash on astype(int). + # We filter into a *local* wrapper instead of mutating the shared reactive + # value (df.set would drop those rows from every other analysis tab too). + if "PY" in data.columns and data["PY"].isna().any(): + data = data[data["PY"].notna()] + + class _LocalDF: + """Lightweight df.get() shim so cocMatrix sees the filtered rows.""" + def __init__(self, d): self._d = d + def get(self): return self._d + df = _LocalDF(data) + # Calculate the number of publications per year for each source WSO = cocMatrix(df, Field="SO") if WSO.shape[1] == 1: diff --git a/functions/get_trendtopics.py b/functions/get_trendtopics.py index 1d2f1df3a..55c06a519 100644 --- a/functions/get_trendtopics.py +++ b/functions/get_trendtopics.py @@ -50,6 +50,12 @@ def get_trend_topics(df, ngram, field_tt, time_window, file_upload_terms_tt, fil # Get trend topics trend_topics = field_by_year(df, field, time_window, word_minimum_frequency, number_of_words_year, remove_terms, synonyms) + # No terms for the chosen field/timespan (e.g. ID empty on PubMed/Dimensions/ + # Lens): return a clean placeholder instead of plotting an empty scatter. + if trend_topics is None or trend_topics.empty: + return empty_plot("No trend topics for the selected field (this source has no data for that field)."), \ + pd.DataFrame(columns=['year_q1', 'year_med', 'year_q3', 'freq', 'item']) + # Plot fig = px.scatter(trend_topics, x='year_med', y='item', size='freq', hover_data=['year_q1', 'year_q3'], height=800) fig.update_layout( @@ -96,8 +102,13 @@ def get_trend_topics(df, ngram, field_tt, time_window, file_upload_terms_tt, fil return fig, trend_topics def field_by_year(df, field, timespan, min_freq, n_items, remove_terms=None, synonyms=None): - # Create co-occurrence matrix + # Create co-occurrence matrix. cocMatrix returns None when the chosen field + # is empty for this source (e.g. Keywords Plus / ID is absent in PubMed, + # Dimensions and Lens exports). Return an empty, well-typed frame so the + # caller can render a clean "no data" plot instead of crashing on None.sum. A = cocMatrix(df, Field=field, binary=False, remove_terms=remove_terms, synonyms=synonyms) + if A is None: + return pd.DataFrame(columns=['year_q1', 'year_med', 'year_q3', 'freq', 'item']) n = A.sum(axis=0).to_numpy() # Convert to 1D array df = df.get() diff --git a/functions/get_wordcloud.py b/functions/get_wordcloud.py index e902f3bd6..8d14b3c00 100644 --- a/functions/get_wordcloud.py +++ b/functions/get_wordcloud.py @@ -60,7 +60,13 @@ def get_wordcloud(df, ngram, num_of_words_wc, field_wc, file_upload_terms_wc, fi colors = [c for c in mcolors.CSS4_COLORS.values() if is_legible_on_white(c)] sorted_words = sorted(word_frequencies.items(), key=lambda x: x[1], reverse=True) - center_word = sorted_words[0][0] + # The chosen field can be empty for a given source (e.g. Keywords Plus / ID + # is absent in PubMed, Dimensions and Lens exports). With no words there is + # nothing to draw: return an empty result so the caller shows a clean table + # instead of crashing on sorted_words[0]. + if not sorted_words: + return None, table + center_word = sorted_words[0][0] compact_radius = radius * 0.6 diff --git a/functions/get_wordfrequency.py b/functions/get_wordfrequency.py index 1f2b81a06..d2be57dd7 100644 --- a/functions/get_wordfrequency.py +++ b/functions/get_wordfrequency.py @@ -37,18 +37,26 @@ def get_word_frequency(df, ngram, field_wf, file_upload_terms_wf, file_upload_sy # Set ngrams based on word_type ngrams = int(ngram) if field_wf in ['TI', 'AB'] else 1 - data = term_extraction(df, field=field_wf, stemming=False, verbose=False, - ngrams=ngrams, remove_terms=remove_terms, synonyms=synonyms) - data = data.get() - if field_wf == 'TI': - print(data[f"{field_wf}_TM"]) - - # Calculate word frequency + # term_extraction tokenises free text and is only needed for Titles (TI) + # and Abstracts (AB); its output column ``{field}_TM`` is consumed only in + # those two branches. For pre-tokenised keyword fields (ID / DE) it is both + # unnecessary and harmful: on sources where the field is empty (e.g. + # Keywords Plus / ID is absent in PubMed, Dimensions and Lens), + # CountVectorizer raises "empty vocabulary". So run it only for TI/AB. if field_wf in ['AB', 'TI']: + data = term_extraction(df, field=field_wf, stemming=False, verbose=False, + ngrams=ngrams, remove_terms=remove_terms, synonyms=synonyms) + data = data.get() word_freq = keyword_growth(data, tag=f"{field_wf}_TM", top=top_words[1], cdf=(occurrences == 'cumulate'), remove_terms=remove_terms, synonyms=synonyms) else: + data = df.get() word_freq = keyword_growth(data, tag=field_wf, top=top_words[1], cdf=(occurrences == 'cumulate'), remove_terms=remove_terms, synonyms=synonyms) + # No terms for the chosen field on this source (e.g. ID empty on PubMed/ + # Dimensions/Lens): return a clean placeholder instead of an empty melt/plot. + if word_freq is None or word_freq.empty or len(word_freq.columns) <= 1: + return empty_plot("No word-frequency data for the selected field (this source has no data for that field)."), \ + pd.DataFrame(columns=["Year"]) # Select terms between top_words[1] and top_words[2] word_freq = word_freq[['Year'] + word_freq.columns[top_words[0]:top_words[1] + 1].tolist()] @@ -145,9 +153,19 @@ def keyword_growth(df, tag, sep=";", top=10, cdf=True, remove_terms=None, synony for main_term, syns in synonyms.items(): data['Term'] = data['Term'].replace(syns, main_term.upper()) + # Drop rows whose year could not be parsed (PY is a nullable Int64 column, + # so missing years arrive as ). Without this the min()/max() below are + # NAType and range() raises "'NAType' object cannot be interpreted as int". + data = data.dropna(subset=['Year']) + data = data[data['Term'].astype(str).str.strip() != ""] + # Empty field for this source (e.g. ID absent in PubMed/Dimensions/Lens): + # hand back just the Year column so the caller shows a clean placeholder. + if data.empty: + return pd.DataFrame(columns=['Year']) + # Aggregazione freq = data.groupby(['Term', 'Year']).size().reset_index(name='Freq') - year_range = range(data['Year'].min(), data['Year'].max() + 1) + year_range = range(int(data['Year'].min()), int(data['Year'].max()) + 1) # Selezione dei termini più frequenti top_terms = freq.groupby('Term')['Freq'].sum().nlargest(top).index diff --git a/functions/get_worldmapcollaboration.py b/functions/get_worldmapcollaboration.py index 9edafa879..bd5859610 100644 --- a/functions/get_worldmapcollaboration.py +++ b/functions/get_worldmapcollaboration.py @@ -1,7 +1,10 @@ from www.services import * import pandas as pd -import geopandas as gpd +try: + import geopandas as gpd +except ImportError: + gpd = None import networkx as nx import plotly.express as px import plotly.graph_objects as go diff --git a/requirements.txt b/requirements.txt index d94f94d9f..e30a71602 100644 Binary files a/requirements.txt and b/requirements.txt differ diff --git a/sources/new/COCHRANE/citation-export.txt b/sources/new/COCHRANE/citation-export.txt deleted file mode 100644 index 07b28e609..000000000 --- a/sources/new/COCHRANE/citation-export.txt +++ /dev/null @@ -1,3122 +0,0 @@ -Record #1 of 151 -ID: CN-02521950 -AU: Levin G -AU: Harrison R -AU: Meyer R -AU: Ramirez PT -TI: Impact of podcasting on novel and conventional measures of academic impact -SO: International journal of gynecological cancer -YR: 2023 -VL: 33 -NO: 2 -PG: 183‐189 -PM: PUBMED 36631152 -PT: Journal article -KY: Bibliometrics; Humans; Neoplasms; Social Media -DOI: 10.1136/ijgc-2022-004114 -AB: OBJECTIVE: Altmetric Attention Score (AAS) is an alternative metric for estimating the impact of academic publications. We studied the association of using podcasting to highlight publications about gynecological cancer with AAS and citation scores. METHODS: Articles that were featured in the International Journal of Gynecological Cancer (IJGC) podcast series January 2019 to September 2022 were matched 1:1 to control articles by the journal in which the article was published, study topic and design, single/multicenter data, and year of publication. Podcast articles were compared with matched‐controls by citation metrics and altmetric scores. RESULTS: A total of 99 podcasted articles published in 16 journals were matched. Median AAS was significantly higher in the podcast group than the matched‐control group (22 (14‐42) vs 5 (1‐17), p<0.001). In a multivariable regression analysis, podcasting was the only factor associated with a high AAS (adjusted odds ratio (aOR) 8.6, 95% CI 3.8 to 19.7). In the podcast group, the median number of citations per year was higher than matched‐control studies (5.5 (3.0‐12.7) vs 4.5 (2.0‐9.5), p=0.047). The only article characteristics that were independently associated with ≥12 citations per year were if the publication described a randomized controlled trial (aOR 4.7, 95% CI 1.6 to 13.6) or featured cervical carcinoma as the subject focus (aOR 2.9, 95% CI 1.3 to 6.5). Compared with all articles published in IJGC during the study period, articles that were featured in a podcast had higher median citations per year (5 (2‐10) vs 1 (0‐2.5), p<0.001). CONCLUSION: When compared with matched‐controls, podcasting an article is associated with a higher AAS but is not associated with generating a high (≥12) number of citations per year. When compared with all articles published in the same journal during the same study period, articles that were featured in a podcast had higher median citations per year. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02521950/full - - -Record #2 of 151 -ID: CN-01724674 -AU: Cai Y -AU: Zhao T-M -AU: Wang R -TI: Bibliometric analysis of Chinese research papers on biofilm -SO: Chinese journal of evidence-based medicine -YR: 2008 -VL: 8 -NO: 11 -PG: 1016‐1019 -XR: EMBASE 352774761 -PT: Journal article -KY: *bibliometrics; *biofilm; *medical research; Article; China; Data base; Financial management; Information processing; Information retrieval; Medline; Methodology; Pseudomonas aeruginosa; Quality control; Randomized controlled trial; Staphylococcus -AB: Objective: To investigate the development of biofilm research over the last 10 years in China based on a bibliometric approach. Methods: We searched PubMed (1997 to 2007), China Hospital Knowledge Database (1997 to 2007), and VIP Chinese Journal Database (1997 to 2007). Quality assessment and data collection were performed by two reviewers independently. The amount of literature, research institutions, financial assistance, and contents of biofilm research were analyzed. Results: A total of 240 Chinese papers were included. Colleges were the leading research institutions in China, and most of research focused on pseudomonas aeruginosa and staphylococci, primarily based on in vitro models. Available antibiotics were the main measures for biofilm control. Only 4 RCTs with a C grade in terms of methodological quality were included. Conclusion: Biofilm research in China can keep pace with the international development, but its integration with engineering, material science and immunology needs to be strengthened. © 2008 Editorial Board of Chin J Evid‐based Med. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01724674/full - - -Record #3 of 151 -ID: CN-02390172 -AU: Frachtenberg E -AU: Kaner RD -TI: Underrepresentation of women in computer systems research -SO: PloS one -YR: 2022 -VL: 17 -NO: 4 -PG: e0266439 -PM: PUBMED 35385516 -PT: Journal article -KY: Bibliometrics; Computer Systems; Female; Humans; Male; Research Personnel -DOI: 10.1371/journal.pone.0266439 -AB: The gender gap in computer science (CS) research is a well‐studied problem, with an estimated ratio of 15%‐30% women researchers. However, far less is known about gender representation in specific fields within CS. Here, we investigate the gender gap in one large field, computer systems. To this end, we collected data from 72 leading peer‐reviewed CS conferences, totalling 6,949 accepted papers and 19,829 unique authors (2,946 women, 16,307 men, the rest unknown). We combined these data with external demographic and bibliometric data to evaluate the ratio of women authors and the factors that might affect this ratio. Our main findings are that women represent only about 10% of systems researchers, and that this ratio is not associated with various conference factors such as size, prestige, double‐blind reviewing, and inclusivity policies. Author research experience also does not significantly affect this ratio, although author country and work sector do. The 10% ratio of women authors is significantly lower than the 16% in the rest of CS. Our findings suggest that focusing on inclusivity policies alone cannot address this large gap. Increasing women's participation in systems research will require addressing the systemic causes of their exclusion, which are even more pronounced in systems than in the rest of CS. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02390172/full - - -Record #4 of 151 -ID: CN-02657883 -AU: Trueger NS -AU: Aly E -AU: Haneuse S -AU: Huang E -AU: Berkwits M -TI: Randomized Clinical Trial Visual Abstract Display and Social Media-Driven Website Traffic -SO: JAMA -YR: 2023 -VL: 330 -NO: 16 -PG: 1583‐1585 -PM: PUBMED 37773505 -XR: EMBASE 2028073082 -PT: Journal article -KY: *Social Media; *social media; Bibliometrics; Controlled study; Human; Humans; Letter; Randomized controlled trial; Social Networking -DOI: 10.1001/jama.2023.16839 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02657883/full - - -Record #5 of 151 -ID: CN-01718002 -AU: Bohl MA -AU: Turner JD -AU: Little AS -AU: Nakaji P -AU: Ponce FA -TI: Assessing the Relevancy of "Citation Classics" in Neurosurgery. Part II: foundational Papers in Neurosurgery -SO: World neurosurgery -YR: 2017 -VL: 104 -PG: 939‐966 -PM: PUBMED 28438655 -XR: EMBASE 616717418 -PT: Journal article -KY: *Bibliometrics; *neurosurgery; Clinical decision making; Controlled clinical trial; Controlled study; History, 20th Century; History, 21st Century; Human; Humans; Medicine; Neurosurgeon; Neurosurgery [*history]; Prospective study; Publications [*history]; Randomized controlled trial; Spine; Student; United States; Web of Science -DOI: 10.1016/j.wneu.2017.03.150 -AB: Background: The second part of this study reanalyzes Ponce and Lozano's (2010) list of classics to create a new list of “foundational” articles in neurosurgery. Ponce and Lozano (2010) previously published a list of 106 neurosurgery classics, as defined by Garfield and his 400 citation criterion. Methods: We used the Web of Science citation reports to create graphs for each study showing the total citations it received as a function of time. Each graph was subjectively analyzed independently and scored as “foundational” or “classic only,” based on whether the trend of citations received per year was uptrending, neutral, or downtrending. Results: Of the 101 evaluated classics, 53 qualified as foundational. Over half of these studies were published in Journal of Neurosurgery (13), New England Journal of Medicine (12), or Lancet (5). Grading systems, randomized trials, and prospective studies were most likely to achieve foundational status. Only 30% of functional and 17% of endovascular classics qualified as foundational (compared with 100% of spine classics), suggesting that these fields are rapidly changing or less mature subspecialties still developing a foundational literature base. Conclusion: By assessing citation counts as a function of time, we are able to differentiate classic neurosurgical studies that are critical to modern‐day practice from those that are primarily of historic interest. Given the exponential growth of literature in our field, analyses such as these will become increasingly important to both trainees and senior neurosurgeons who strive to educate themselves on the data that drive modern‐day clinical decision making. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01718002/full - - -Record #6 of 151 -ID: CN-02390381 -AU: Gowda PC -AU: Lobner K -AU: Hafezi-Nejad N -AU: Weiss CR -TI: Bibliometric analysis of interventional radiology studies in PubMed-indexed literature from 1991 to 2020 -SO: Clinical imaging -YR: 2022 -VL: 85 -PG: 43‐47 -PM: PUBMED 35240478 -PT: Journal article -KY: *Obstetrics; *Radiology, Interventional; Bibliometrics; Child; Female; Humans; Pregnancy; PubMed -DOI: 10.1016/j.clinimag.2022.02.024 -AB: PURPOSE: To evaluate interventional radiology (IR) research over time based on the study type of published articles and the visibility of articles to non‐radiology clinicians. METHODS: We performed a search of all PubMed‐indexed literature from January 1, 1991, through November 11, 2020, for clinical IR articles classified by their study type, categorized as: 1) meta‐analyses/systematic reviews/practice guidelines; 2) randomized controlled trials; 3) non‐randomized controlled trials; and 4) longitudinal/observational studies. Clinical IR articles were defined as those that met keyword criteria constructed from Society of Interventional Radiology procedure guides. Data were also collected on medical specialty journal categories that published IR‐related articles. RESULTS: When we examined the first vs. the last decade of our study period, the number of IR articles published increased across all study types: randomized controlled trials (374 to 2620; 601% change), longitudinal/observational studies (2324 to 12,447; 436%), meta‐analyses/systematic reviews/practice guidelines (1179 to 6135; 420%), non‐randomized controlled trials (471 to 2161; 359%). The journal categories with the highest mean percentage increase of IR articles across all study types were obstetrics and gynecology (659%), peripheral vascular disease (342%), and emergency medicine (221%). We found a decrease of IR articles published in surgery (‐6.0%), pediatrics (‐14%), and pulmonary (‐21%) journals. CONCLUSION: The number of IR articles grew quickly and at a similar rate compared with all PubMed‐indexed articles and increased as a proportion of articles published in non‐imaging specialty journals. This indicates greater visibility of IR studies for all clinicians and is encouraging towards the advancement of IR techniques. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02390381/full - - -Record #7 of 151 -ID: CN-02000076 -AU: Palacios-Marqués AM -AU: Carratala-Munuera C -AU: Martínez-Escoriza JC -AU: Gil-Guillen VF -AU: Lopez-Pineda A -AU: Quesada JA -AU: Orozco-Beltrán D -TI: Worldwide scientific production in obstetrics: a bibliometric analysis -SO: Irish journal of medical science -YR: 2019 -VL: 188 -NO: 3 -PG: 913‐919 -PM: PUBMED 30627959 -PT: Journal article -KY: Bibliometrics; Female; Humans; Obstetrics [*organization & administration]; Research Design [*trends] -DOI: 10.1007/s11845-018-1954-3 -AB: BACKGROUND: Randomised clinical trials are considered to be the most reliable study design for assessing the efficacy and safety of health interventions. AIMS: To analyse worldwide obstetrics research carried out through randomised clinical trials, from 2002 to 2013. METHODS: A bibliometric analysis was performed. Publications on obstetrics that were published journals indexed in the MEDLINE database from 2002 to 2013 were analysed. The major medical subject headings used in the search were obstetrics, pregnancy complications and obstetrics surgical procedures. The main study outcome was index of research productivity. RESULTS: Our study search strategy yielded a total of 142,659 articles and 9967 clinical trials. The growth rate of scientific production in obstetrics during this period was 55.43% (n = 5094). The growth rate of production of randomised clinical trials in this specialty, meanwhile, was 97.84% (n = 544). Most of the identified authors (n = 22,622, 71.21%) published only one paper during the study period. Patterns of co‐authorship among the 20 most productive authors were identified. After applying Bradford's law, six journals in the nucleus (the most prolific journals) were found. Of all the clinical trials in obstetrics published between 2002 and 2013, 10.3% were published in journals belonging to categories other than Obstetrics and Gynecology. The most common research topic in 2002 and 2013 was the use of analgesia and anesthesia in obstetrics. CONCLUSIONS: Total scientific production rate in obstetrics increased from 2002 to 2013, especially randomised clinical trials. However, randomised clinical trials continue to represent a small proportion of total production. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02000076/full - - -Record #8 of 151 -ID: CN-02390247 -AU: Wu H -AU: Cheng K -AU: Tong L -AU: Wang Y -AU: Yang W -AU: Sun Z -TI: Knowledge structure and emerging trends on osteonecrosis of the femoral head: a bibliometric and visualized study -SO: Journal of orthopaedic surgery and research -YR: 2022 -VL: 17 -NO: 1 -PG: 194 -PM: PUBMED 35346273 -PT: Journal article -KY: Bibliometrics; Femur Head; Humans; Osteogenesis; Osteonecrosis; Publications -DOI: 10.1186/s13018-022-03068-7 -AB: BACKGROUND: Osteonecrosis of the femoral head (ONFH) is a common disabling disease with considerable social and economic impacts. Although extensive studies related to ONFH have been conducted in recent years, a specific bibliometric analysis on this topic has not yet been performed. Our study attempted to summarize the comprehensive knowledge map, development landscape, and future directions of ONFH research with the bibliometric approach. METHODS: All publications concerning ONFH published from 2001 to 2020 were identified from Web of Science Core Collection. Key bibliometric indicators were calculated and evaluated using CiteSpace, VOSviewer, and the online bibliometric analysis platform. RESULTS: A total of 2594 publications were included. Our analysis revealed a significant exponential growth trend in the annual number of publications over the past 20 years (R2 = 0.9663). China, the USA, and Japan were the major contributors both from the quality and quantity points of view. Correlation analysis indicated that there was a high positive correlation between the number of publications and gross domestic product (r = 0.774), and a moderate positive correlation between publications and demographic factor (r = 0.673). All keywords were categorized into four clusters including Cluster 1 (etiology and risk factors study); Cluster 2 (basic research and stem cell therapy); cluster 3 (hip‐preserving study); and Cluster 4 (hip replacement study). Stem cell therapy‐related research has been recognized as an important research hotspot in this field. Several topics including exosomes, autophagy, biomarkers, osteogenic differentiation, microRNAs, steroid‐induced osteonecrosis, mesenchymal stem cells, double‐blind, early‐stage osteonecrosis, and asymptomatic osteonecrosis were considered as research focuses in the near future. CONCLUSION: Over the past two decades, increasing attention has been paid to global ONFH‐related research. Our bibliometric findings provide valuable information for researchers to understand the basic knowledge structure, identify the current research hotspots, potential collaborators, and future research frontiers in this field. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02390247/full - - -Record #9 of 151 -ID: CN-02199419 -AU: Wang NL -TI: Proper interpretation of the randomized intervention studies published in influential journals -SO: Zhonghua yan ke za zhi [Chinese journal of ophthalmology] -YR: 2018 -VL: 54 -NO: 4 -PG: 243‐244 -PM: PUBMED 29747352 -XR: EMBASE 627640000 -PT: Journal article -KY: *ophthalmology; *publication; *randomized controlled trial (topic); Bibliometrics; China; Ophthalmology; Periodicals as Topic; Randomized Controlled Trials as Topic; Research; Research Report -DOI: 10.3760/cma.j.issn.0412-4081.2018.04.002 -AB: In recent years, many randomized intervention studies in the field of ophthalmology were published in influential journals such as The Lancet. There have been different voices about these published articles. It is important for academic associations and societies to select the right articles and incorporate the fitting results into the national clinical guidelines based on the proper interpretation and understanding of both the articles and China's national conditions. Chinese ophthalmologists should actively carry out high‐quality clinical researches to meet the needs of developing domestic clinical guidelines and to enhance the international influence of Chinese ophthalmology. (Chin J Ophthalmol, 2018, 54: 243‐244). -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02199419/full - - -Record #10 of 151 -ID: CN-02192335 -AU: Kohut A -AU: Booher M -AU: Naumova AD -AU: Kuhn T -AU: Southern GK -AU: Flowers L -AU: Conrad LB -AU: Gordon AN -AU: Khanna N -TI: Citation classics in gynecologic oncology: a bibliometric analysis -SO: Gynecologic oncology -YR: 2020 -VL: 159 -PG: 305 -XR: EMBASE 2008347228 -PT: Journal article; Conference proceeding -KY: Conference abstract; Controlled study; Female; Human; Randomized controlled trial; Rank sum test; SciSearch; United States; Web of Science -DOI: 10.1016/j.ygyno.2020.05.546 -AB: Objective: The aim of this study was to evaluate the bibliometric characteristics of the most highly cited publications in the field of gynecologic oncology. Method: We performed a bibliometric analysis of citation classics in the field of gynecologic oncology using the Science Citation Index Expanded (SCIE) accessed through the Web of Science Database. The top 50 cited papers in the field were included. Analyses were performed to compare article characteristics before and after 2003 (the median year of publication among all citation classics contained in the study) using the Mann Whitney (Wilcoxon) test for unpaired data. Results: A total of 9,207 articles associated with the field of gynecologic oncology were contained within the Web of Science between 1900 and 2019. The median year of publication of citation classics was 2003 (IQR 2000–2008). Most citation classics were from institutions in the United States (41/50) and randomized controlled trials (27/50). Common journals in which citation classics were published included Journal of Clinical Oncology (21/50), New England Journal of Medicine (7/50), Lancet (5/50), and Gynecologic Oncology (4/50). Median number of citations among analyzed articles was 609 (IQR 429–977). Median number of citations per citation classic before and after 2003 was 623 (IQR 449–1,055) and 597 (IQR 410–876), respectively (P = 0.562). Average number of citations per year before 2003 was 42 (IQR 24–56) and after 2003, 79 (IQR 41–88), respectively (P = 0.004). Conclusion: To date, there has not been a bibliometric analysis of citation classics in the field of gynecologic oncology. Here we aim to identify and characterize citation classics in gynecologic oncology and assess citation trends over time. Most citation classics were found to be U.S. based and randomized controlled trials. There was a statistically significant trend toward increased average citations per year after 2003. We hope this study provides insight into the highest impact papers, as well as their contributions to the field of gynecologic oncology. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02192335/full - - -Record #11 of 151 -ID: CN-00688835 -AU: Swaminathan M -AU: Phillips-Bute BG -AU: Grichnik KP -TI: A bibliometric analysis of global clinical research by anesthesia departments -SO: Anesthesia and analgesia -YR: 2007 -VL: 105 -NO: 6 -CC: Anaesthesia; Pain, Palliative and Supportive Care -PG: 1741‐1746 -PT: Journal article -AB: BACKGROUND: Few studies have investigated the diversity in research conducted by anesthesia‐based researchers. We examined global clinical research attributed to anesthesia departments using Medline and Ovid databases. We also investigated the impact of economic development on national academic productivity. METHODS: We conducted a Medline search for English‐language publications from 2000 to 2005. The search included only clinical research in which institutional affiliation included words relating to anesthesia (e.g., anesthesiology, anesthesia, etc.). Population and gross national income data were obtained from publicly available databases. Impact factors for journals were obtained from Journal Citation Reports (Thomson Scientific). RESULTS: There were 6736 publications from 64 countries in 551 journals. About 85% of all publications were represented by 46 journals. Randomized controlled trials constituted 4685 (70%) of publications. Turkey had the highest percentage of randomized controlled trials (88%). The United States led the field in quantity (20% of total) and mean impact factor (3.0) of publications. Finland had the highest productivity when adjusted for population (36 publications per million population). Publications from the United States declined from 23% in 2000 to 17% in 2005. CONCLUSIONS: Clinical research attributable to investigators in our specialty is diverse, and extends beyond the traditional field of anesthesia and intensive care. The United States produces the most clinical research, but per capita output is higher in European nations. ISSN Electronic 1526‐7598 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-00688835/full - - -Record #12 of 151 -ID: CN-01755319 -AU: Tsay MY -AU: Yang YH -TI: Bibliometric analysis of the literature of randomized controlled trials -SO: Journal of the Medical Library Association : JMLA -YR: 2005 -VL: 93 -NO: 4 -PG: 450‐458 -PM: PUBMED 16239941 -XR: EMBASE 41702479 -PT: Journal article -KY: *medical informatics; *medical literature; *randomized controlled trial; Bibliographic database; Bibliometrics; Clinical trial; Controlled clinical trial; Evidence based medicine; Global Health; Humans; Language; Medline; Models, Statistical; Periodicals as Topic [*statistics & numerical data]; Publication; Publishing [statistics & numerical data]; Randomized Controlled Trials as Topic [*statistics & numerical data]; Review; Software -AB: OBJECTIVE: Evidence‐based medicine (EBM) is a significant issue and the randomized controlled trial (RCT) literature plays a fundamental role in developing EBM. This study investigates the features of RCT literature based on bibliometric methods. Growth of the literature, publication types, languages, publication countries, and research subjects are addressed. The distribution of journal articles was also examined utilizing Bradford's law and Bradford‐Zipf's law. METHOD: The MEDLINE database was searched for articles indexed under the publication type "Randomized Control Trial," and articles retrieved were counted and analyzed using Microsoft Access, Microsoft Excel, and PERL. RESULTS: From 1990 to 2001, a total of 114,850 citations dealing with RCTs were retrieved. The literature growth rate, from 1965 to 2001, is steadily rising and follows an exponential model. Journal articles are the predominant form of publication, and the multicenter study is extensively used. English is the most commonly used language. CONCLUSIONS: Generally, RCTs are found in publications concentrating on cardiovascular disease, cancer, asthma, postoperative condition, health, and anesthetics. Zone analysis and graphical formulation from Bradford's law of scattering shows variations from the standard Bradford model. Forty‐two core journals were identified using Bradford's law. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01755319/full - - -Record #13 of 151 -ID: CN-02260541 -AU: Nandakumar M -AU: Maturana MM -AU: Vouzonis E -TI: The 50 most influential studies on paediatricdiabetic ketoacidosis: a bibliometric analysis -SO: Archives of disease in childhood -YR: 2020 -VL: 105 -NO: SUPPL 1 -PG: A154 -XR: EMBASE 634462482 -PT: Journal article; Conference proceeding -KY: *diabetic ketoacidosis; Attention; Brain edema; California; Child; Clinical article; Conference abstract; Controlled study; Female; Human; Infant; Male; Publishing; Randomized controlled trial; Web of Science -DOI: 10.1136/archdischild-2020-rcpch.369 -AB: Objectives Diabetic ketoacidosis (DKA) in paediatrics is a common condition and often the firstpresentation of type 1 diabetes mellitus in children. The number of citations a study receives can be usedas a marker of academic influence, and can help to identify strong and weak areas of research within aparticular field. We aimed to identify the 50 most influential studies relating to paediatric DKA by citationnumber, and analyse their characteristics. Methods The Web of Science database was used to determine the studies that were most frequentlycited. We searched for studies that included 'Diabetic ketoacidosis' or 'DKA' along with 'paediatric' or'children' or 'child' or 'infant' in the title. Data extracted included publication year, article type and focus,publication journal, institution and country, level of evidence (LOE) and total citation number. Publishedguidelines were excluded from the LOE rankings. Citation density was also calculated as number ofcitations per year since publication. Results Our search returned 410 studies. The top 50 studies were published between 1976 to 2014. Themost common study topics were epidemiology and pathophysiology, with many studies relating tocerebral oedema (n=19). The mean number of citations was 74.7 (standard deviation 60.3, range 28‐375). These were published in 21 journals, led by Pediatric Diabetes (n=9). They originated from 9different countries, with institutions from the United States of America publishing the majority (n=30),and the University of California, Davis publishing the most studies (n=7). One RCT was identified, 39 non‐randomised clinics studies were included. The remainder included reviews, basic science studies andguidelines. 10 studies were classified as LOE 1, and 11 studies as LOE 4. Conclusions The 50 top cited studies on paediatric DKA relate mostly to epidemiology andpathophysiology. Cerebral oedema in paediatric DKA patients has received increased attention byresearchers and institutions. LOE was low, with only one RCT identified. Though these studies are themost influential in the field, perhaps the evidence base for this field would benefit from further highquality trials. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02260541/full - - -Record #14 of 151 -ID: CN-01713484 -AU: Vickers AJ -TI: Bibliometric analysis of randomized trials in complementary medicine -SO: Complementary therapies in medicine -YR: 1998 -VL: 6 -NO: 4 -CC: Complementary Medicine -PG: 185‐189 -XR: EMBASE 29017629 -PT: Journal article -KY: *alternative medicine; *medical information; Acupuncture; Article; Bone disease /therapy; Cardiovascular disease /therapy; Fatigue /therapy; Herbal medicine; Medical literature; Meditation; Musculoskeletal disease /therapy; Postoperative complication /complication /therapy; Randomized controlled trial; Register; Relaxation training -DOI: 10.1016/S0965-2299(98)80026-5 -AB: Objective: To determine the following features of randomized trials in complementary medicine: the extent to which they are indexed on Medline, the journals in which they are published, dates of publication, the therapies and conditions most commonly the focus of study. Design: Bibliometric analysis of the registry of randomized trials of the Cochrane Collaboration field in Complementary Medicine. Outcome measures: The number of trials in each category. Results: There were 3774 randomized trials on the registry of which 3072 (81%) were indexed on Medline. However, only about a third of these references could be easily found with a Medline search. Trials were published in a total of 965 different journals. Most trials (84%) were published in a conventional medical journal. The number of trials is increasing rapidly, having approximately doubled every 5 year period since 1965. There was a large variation in the number of trials for different complementary therapies. There were a high number of trials in acupuncture (554), herbal medicine (804) and meditation and relaxation techniques (643) but few trials in aromatherapy (47) and osteopathy (18). There were many trials in cardiovascular disease (501), musculoskeletal disorders (386) and surgery‐related symptoms (293), but few in fatigue disorders (11). Conclusion: Medline is an incomplete source of randomized trials in complementary medicine. Searching of Medline could be significantly enhanced by changes to keywords and improved data on type of publication. The conditions and therapies subject to trials in complementary medicine do not provide an accurate reflection of clinical practice. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01713484/full - - -Record #15 of 151 -ID: CN-01940181 -AU: Lu C-L -AU: Qiao S-Y -AU: Jin X-Y -AU: Tian Z-Y -AU: Liu J-P -TI: Evidence base of clinical studies on fasting therapy: a bibliometric analysis -SO: Advances in integrative medicine -YR: 2019 -VL: 6 -PG: S142 -XR: EMBASE 2001763208 -PT: Journal article; Conference proceeding -KY: *intermittent fasting; Adult; Adverse event; Blood pressure; Body mass; Calorie; Case study; China; Cohort analysis; Conference abstract; Diabetes mellitus; Female; Fruit; Germany; Glucose blood level; Health care management; Human; Major clinical study; Male; Metabolic syndrome X; Obesity; Palliative therapy; Randomized controlled trial; Vegetable -DOI: 10.1016/j.aimed.2019.03.415 -AB: Background: Fasting therapy refers to calorie and diet restriction for different diseases/condition. Clinical studies pay more attention to its safety and health benefits. The aim is to summarize current clinical studies of fasting for health management. Methods: We searched 6 Chinese and English databases from the inception to July 2018 to identify relative clinical studies and extracted data in duplicate. Data were presented by counts, percentage and frequency. Result: 49 studies (involving 20,357 participants) published in 1990‐2018 were identified, mainly including 30.6% randomized clinical trials (RCTs), 28.6% case series or case reports and 18.4% cohort studies. The top 3 diseases/condition were type‐2 diabetes, obesity and metabolic syndrome, most conducted in China, Germany and the UK. 18 studies applied fasting for prevention, 29 studies for cure, and 2 studies for both purposes. The modality performed as intermittent fasting and modified fasting, to intake low‐calorie with vegetables and fruits on alternate days or on 5 continue days per week. The course lasted for periods of 1‐4weeks and continued to 1–2 years. 29 (59.2%) studies used fasting alone whilst others combined with conventional symptomatic treatment. The most frequently reported outcomes were weight, BMI, blood pressure and blood glucose level. 67.3% studies reported positive effects, 24.5% studies reported uncertain effects and 8.2% studies reported negative effects. No serious adverse event related to fasting was reported. Conclusions: With limited evidence, fasting therapy is applied in diseases/conditions measured by weight and blood indices. Well‐designed, adequately powered and further rigorous studies are recommended to confirm its effects. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01940181/full - - -Record #16 of 151 -ID: CN-02746607 -AU: Silva FM -AU: Amorim Adegboye AR -AU: Curioni C -AU: Gomes F -AU: Collins GS -AU: Kac G -AU: Cook J -AU: Ismail LC -AU: Page MJ -AU: Khandpur N -AU: et al. -TI: Reporting completeness of nutrition and diet-related randomised controlled trials protocols -SO: Clinical nutrition (Edinburgh, Scotland) -YR: 2024 -VL: 43 -NO: 7 -PG: 1626‐1635 -PM: PUBMED 38795681 -XR: CINAHL 178023804 -PT: Journal article -KY: *Clinical Trial Protocols as Topic; *Diet; *Randomized Controlled Trials as Topic; Adult; Aged; Aged, 80 and Over; Bibliometrics; Checklist [standards]; Checklists; Descriptive Statistics; Diet; Editorial Policies; Guidelines as Topic; Human; Humans; Linear Regression; Methods; Multivariate Analysis; Periodicals as Topic; Randomized Controlled Trials; Research Design [standards]; SARS‐CoV‐2; Standards; Study Design -DOI: 10.1016/j.clnu.2024.04.038 -AB: BACKGROUND AND AIMS: There is a need to consolidate reporting guidance for nutrition randomised controlled trial (RCT) protocols. The reporting completeness in nutrition RCT protocols and study characteristics associated with adherence to SPIRIT and TIDieR reporting guidelines are unknown. We, therefore, assessed reporting completeness and its potential predictors in a random sample of published nutrition and diet‐related RCT protocols. METHODS: We conducted a meta‐research study of 200 nutrition and diet‐related RCT protocols published in 2019 and 2021 (aiming to consider periods before and after the start of the COVID pandemic). Data extraction included bibliometric information, general study characteristics, compliance with 122 questions corresponding to items and subitems in the SPIRIT and TIDieR checklists combined, and mention to these reporting guidelines in the publications. We calculated the proportion of protocols reporting each item and the frequency of items reported for each protocol. We investigated associations between selected publication aspects and reporting completeness using linear regression analysis. RESULTS: The majority of protocols included adults and elderly as their study population (n = 73; 36.5%), supplementation as intervention (n = 96; 48.0%), placebo as comparator (n = 89; 44.5%), and evaluated clinical status as the outcome (n = 80; 40.0%). Most protocols described a parallel RCT (n = 188; 94.0%) with a superiority framework (n = 141; 70.5%). Overall reporting completeness was 52.0% (SD = 10.8%). Adherence to SPIRIT items ranged from 0% (n = 0) (data collection methods) to 98.5% (n = 197) (eligibility criteria). Adherence to TIDieR items ranged from 5.5% (n = 11) (materials used in the intervention) to 98.5% (n = 197) (description of the intervention). The multivariable regression analysis suggests that a higher number of authors [β = 0.53 (95%CI: 0.28‐0.78)], most recent published protocols [β = 3.19 (95%CI: 0.24‐6.14)], request of reporting guideline checklist during the submission process by the journal [β = 6.50 (95%CI: 2.56‐10.43)] and mention of SPIRIT by the authors [β = 5.15 (95%CI: 2.44‐7.86)] are related to higher reporting completeness scores. CONCLUSIONS: Reporting completeness in a random sample of 200 diet or nutrition‐related RCT protocols was low. Number of authors, year of publication, self‐reported adherence to SPIRIT, and journals' endorsement of reporting guidelines seem to be positively associated with reporting completeness in nutrition and diet‐related RCT protocols. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02746607/full - - -Record #17 of 151 -ID: CN-02400811 -AU: Ladeiras-Lopes R -AU: Vidal-Perez R -AU: Santos-Ferreira D -AU: Alexander M -AU: Baciu L -AU: Clarke S -AU: Crea F -AU: Lüscher TF -TI: Twitter promotion is associated with higher citation rates of cardiovascular articles: the ESC Journals Randomized Study -SO: European heart journal -YR: 2022 -VL: 43 -NO: 19 -PG: 1794‐1798 -PM: PUBMED 35567549 -XR: EMBASE 637999958 -PT: Journal article -KY: *publication; *social media; Bibliometrics; Controlled study; Human; Humans; Journal Impact Factor; Journal impact factor; Periodicals as Topic; Randomized controlled trial; Social Media -DOI: 10.1093/eurheartj/ehac150 -AB: The association between the dissemination of scientific articles on Twitter and online visibility (as assessed by the Altmetric Score) is still controversial, and the impact on citation rates has never been rigorously addressed for cardiovascular medicine journals using a randomized design. The ESC Journals Study randomized 695 papers published in the ESC Journal Family (March 2018‐May 2019) for promotion on Twitter or to a control arm (with no active tweeting from ESC channels) and aimed to assess whether Twitter promotion was associated with an increase in citation rates (primary endpoint) and of the Altmetric Score. This is the final analysis including 694 articles (one paper excluded due to retraction). After a median follow‐up of 994 days (interquartile range: 936‐1063 days), Twitter promotion of articles was associated with a 1.12 (95% confidence interval: 1.08‐1.15) higher rate of citations, and this effect was independent of the type of article. Altmetric Attention Score and number of users tweeting were positive predictors for the number of citations. A social media strategy of Twitter promotion for cardiovascular medicine papers seems to be associated with increased online visibility and higher numbers of citations. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02400811/full - - -Record #18 of 151 -ID: CN-02354681 -AU: Yang K -AU: Baek HG -AU: Cho DC -AU: Jung YG -AU: Lee S -AU: Park JH -TI: Comparative analysis of the recent publication trends in 4 representative journals in the spine field -SO: Medicine -YR: 2021 -VL: 100 -NO: 45 -PG: e27716 -PM: PUBMED 34766577 -PT: Journal article -KY: *Neurosurgery; *Orthopedics; *Periodicals as Topic; Bibliometrics; Humans; Neurosurgical Procedures; Spine -DOI: 10.1097/MD.0000000000027716 -AB: We have analyzed and compared the publication trends in 4 representative spinal journals [Spine, European Spinal Journal (EUS), The Spine Journal (TSJ), and the Journal of Neurosurgery ‐ Spine (JNS spine)] from 2016 to 2018.A total of 3784 articles were published in the 4 representative journals: 1358, 1128, 685, and 613 articles in Spine, EUS, TSJ, and JNS spine, respectively. We compared and analyzed each periodical for the time taken (days) for the publication process, the distribution of specialties of the corresponding author, multicity of the investigative institutions, main disease entity, study type, and design.The period from submission to online publication was 133, 216, 181, and 318 days in Spine, EUS, TSJ, and JNS spine, respectively. Corresponding authors with orthopedic specialties were more common in Spine, EUS, and TSJ than in JNS spine. Of particular note, corresponding authors who were neurosurgeons were the majority (55.8%) only in JNS spine. Single institution articles were by far the most common (average 92.8%) in all 4 journals. In all of the analyzed journals, the proportion of degenerative diseases was dominant with an average of 44.9%. The most frequent study type in all 4 journals was a clinical article (79.6, 72.1, 63.3, and 63.1%, respectively). In general, meta‐analyses (average 4%) and randomized controlled comparative studies (average 5.2%) accounted for a very low percentage of the study types.We believe that periodic analyses and comparisons of the characteristics of representative spine journals will help to shape the direction of future improvements. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02354681/full - - -Record #19 of 151 -ID: CN-02630353 -AU: Xiao Z -AU: Chen W -AU: Wei Z -AU: Zhang Q -AU: Tang G -TI: Global trends and hotspots in the application of platelet-rich plasma in knee osteoarthritis: a bibliometric analysis from 2008 to 2022 -SO: Medicine -YR: 2023 -VL: 102 -NO: 47 -PG: e35854 -PM: PUBMED 38013292 -PT: Journal article -KY: *Osteoarthritis, Knee [therapy]; *Platelet‐Rich Plasma; Bibliometrics; Humans; Inflammation; Knee Joint -DOI: 10.1097/MD.0000000000035854 -AB: Platelet‐rich plasma (PRP) injection therapy holds great promise in improving knee cartilage repair. This bibliometric analysis aimed to explore the research landscape in the application of PRP for knee osteoarthritis (KOA) over the last 15 years. All articles investigating PRP in the application of KOA were retrieved from the web of science core collection. Publications were analyzed using R software, VOS Viewer, CiteSpace, Microsoft Excel, and an online bibliometric platform (https://bibliometric.com/). A total of 815 articles were identified, 6 articles from 2010 had the highest average number of citations in the local database. Filardo G., Kon E., Cole B.J., Marcacci M., and Di Martino A. are the top 5 authors based on the H‐index. The "American Journal Of Sports Medicine" is the most authoritative journal in the field of PRP application in KOA. The United States is the global leader in this field, with European countries playing a pivotal role in collaborative exchanges. Taipei Medical University is the most prolific institution and Shahid Beheshti University Medical Sciences in Iran the fastest‐rising institution. The keywords "Hyaluronic Acid," "cartilage," "growth factors," "mesenchymal stem cells," "intra‐articular injection," "pain," "inflammation," "double‐blind," "management," "placebo," "stromal cells," "rheumatoid arthritis," and "pathology" appeared most frequently. "Exercise," "volume," and "physical‐activity" are the latest hot topics. Future trends in this field include the standardization of injection components, injection sites, and injection methods, the modulation of useful or harmful growth factor receptor expression, sports management, and the validation of contraindications to PRP. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02630353/full - - -Record #20 of 151 -ID: CN-02510072 -AU: Gan P -AU: Pan X -AU: Huang S -AU: Xia H -AU: Zhou X -AU: Tang X -TI: Current status of coronavirus disease 2019 vaccine research based on bibliometric analysis -SO: Human vaccines & immunotherapeutics -YR: 2022 -VL: 18 -NO: 6 -PG: 2119766 -PM: PUBMED 36494998 -PT: Journal article -KY: Antibodies; Bibliometrics; COVID‐19 Vaccines; COVID‐19 [prevention & control]; Humans; Vaccination -DOI: 10.1080/21645515.2022.2119766 -AB: Vaccination is considered the most effective way to reduce the impact of coronavirus disease 2019 (COVID‐19). Several new vaccines have been manufactured. This study aimed to assess the current status and prospects of COVID‐19 vaccine research using a bibliometric analysis. We analyzed 3,954 scientific articles on COVID‐19 vaccines in the Web of Science Core Collection (WoSCC). CiteSpace and VOSviewer were used for bibliometric visualization. Original articles and reviews were used for the analysis. A total of 2,783 (70.38%) studies were published in 2021. The USA contributed the highest, publishing 1,390 articles with 41,788 citations, followed by China and the UK. The USA's primary collaborators were the UK (n = 133), China (n = 87), and Canada (n = 65). The most active institutions were the University of Oxford and Harvard Medical School, while Emory University was the most influential. The Vaccines journal had the most number of publications (402). The most cited journal was the New England Journal of Medicine. In 2021, the focus was on RNA vaccines, attitudes toward vaccination, and hesitancy. In contrast, studies in 2022 focused on vaccine double‐blind trials, viral mutations, and antibodies. In the context of rapid virus transmission, vaccine studies on immunogenicity, spike proteins, efficacy, safety, and antibody response have been prioritized. Additional phased clinical trials are needed to determine the effectiveness, acceptance, and side effects of vaccines against mutated strains of the virus. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02510072/full - - -Record #21 of 151 -ID: CN-02538936 -AU: Yang S -AU: Yu D -AU: Liu J -AU: Qiao Y -AU: Gu S -AU: Yang R -AU: Chai X -AU: Wang W -TI: Global publication trends and research hotspots of the gut-liver axis in NAFLD: a bibliometric analysis -SO: Frontiers in endocrinology -YR: 2023 -VL: 14 -PG: 1121540 -PM: PUBMED 36967792 -PT: Journal article -KY: Bibliometrics; Humans; Inflammation; Liver Cirrhosis; Non‐alcoholic Fatty Liver Disease [epidemiology] -DOI: 10.3389/fendo.2023.1121540 -AB: BACKGROUND: Nonalcoholic Fatty Liver Disease(NAFLD)refers to a spectrum of diseases ranging from simple liver steatosis to nonalcoholic steatohepatitis (NASH) and cirrhosis. Bidirectional cross‐talk between the gut‐liver axis plays an important role in the pathogenesis of NAFLD. To learn more about the gut‐liver axis in NAFLD, this study aims to provide a comprehensive analysis from a bibliometric perspective. METHOD: Literature related to the gut‐liver axis in NAFLD from 1989 to 2022 was extracted from the Web of Science Core Collection. Based on Microsoft Excel, CiteSpace and Vosviewer, we conducted to analyze the number of publications, countries/regions, institutions, authors, journals, references, and keywords. RESULTS: A total of 1,891 literature since 2004 was included, with the rapid growth of the number of papers on the gut‐liver axis in NAFLD annually. These publications were mainly from 66 countries and 442 institutions. Of the 638 authors analyzed, Bernd Schnabl was the one with the most publications, and Patrice D. Cani was the one with the most co‐citations. International Journal of Molecular Sciences is the journal with the most articles published, and Hepatology is the journal with the most citations. The most common keywords are gut microbiota, inflammation, and insulin instance, which are current research hotspots. Short‐chain fatty acid, in vitro, randomized controlled trial in clinical, and diabetes mellitus represent the research frontiers in this field and are in a stage of rapid development. CONCLUSION: This is the first study to conduct a comprehensive bibliometric analysis of publications related to the gut‐liver axis in NAFLD. This study reveals that gut microbiota, inflammation, insulin resistance, short‐chain fatty acids, and randomized controlled trial will be the hotspots and new trends in the gut‐liver axis in NAFLD research, which could provide researchers with key research information in this field and is helpful for further exploration of new research directions. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02538936/full - - -Record #22 of 151 -ID: CN-02232196 -AU: Misso D -AU: Zhen E -AU: Kelly J -AU: Collopy D -AU: Clark G -TI: A progressive scholarly acceptance analysis of robot-assisted arthroplasty: a review of the literature and prediction of future research trends -SO: Journal of robotic surgery -YR: 2021 -VL: 15 -NO: 5 -PG: 813‐819 -PM: PUBMED 33389627 -XR: EMBASE 2007727841 -PT: Journal article -KY: *prediction; *robotics; *total hip replacement; *total knee arthroplasty; Arthroplasty, Replacement, Knee; Article; Bibliometrics; Controlled study; English (language); Human; Human experiment; Humans; Randomized controlled trial; Robotic Surgical Procedures [methods]; Robotics; Surgical technique -DOI: 10.1007/s11701-020-01173-5 -AB: Robot‐assisted arthroplasty (RAA) is increasingly practised in orthopaedic surgery. The aim of this study was to perform a bibliometric analysis of all published primary research into RAA and to apply the Progressive Scholarly Acceptance (PSA) model to evaluate its acceptance as an orthopaedic surgical technique. A literature search was performed that included all peer‐reviewed, primary, English language publications on RAA from its introduction in 1992 up to 2019. RAA was defined as robot‐assisted hip or knee arthroplasty. A bibliometric analysis was performed to categorise articles by type of study and level of evidence. Studies were also categorised as initial investigations (II) or refining studies (RS). A PSA analysis was performed, with the end‐point being defined as the point in time when the number of RS exceeded the number of II. Of the 199 studies originating from 19 countries and 101 institutions, only 16 (8.04%) were randomised‐controlled trials. Fifty‐one percent of studies had been published since 2015. Using PSA analysis, 161 (80.9%) studies were categorised as II and 38 (19.1%) were categorised as RS. This demonstrates that RAA has not yet reached the point of scholarly acceptance. Scholarly acceptance of RAA as an orthopaedic surgical technique has yet to be reached. However, there has been an exponential increase in the number of publications on RAA in the last 5 years, reflecting renewed interest this technique. We predict that, for the next 5 years, RAA will remain in the experimental phase due to the rapid development of new technology in this field. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02232196/full - - -Record #23 of 151 -ID: CN-02231066 -AU: Sugumar K -AU: Hue JJ -AU: Ahorukomeye P -AU: Rothermel LD -AU: Ocuin LM -AU: Hardacre JM -AU: Ammori JB -AU: Winter JM -TI: Defining Common Features in High Impact and Highly Cited Journal Articles on Pancreatic Tumors: an Analysis of 1044 Studies over the Past Decade -SO: Annals of surgery -YR: 2021 -VL: 274 -NO: 6 -PG: 977‐984 -PM: PUBMED 33351479 -XR: EMBASE 633876307 -PT: Journal article -KY: *pancreas tumor; Article; Bibliometrics; Complication; Controlled study; Human; Humans; Journal Impact Factor; Pancreatectomy; Pancreatic Neoplasms [*surgery]; Randomized controlled trial -DOI: 10.1097/SLA.0000000000004670 -AB: INTRODUCTION: Surgical researchers seek to publish their findings in esteemed surgical journals to advance science and their careers. A detailed investigation of study and manuscript attributes in a specific research area, like pancreatic neoplasia, may yield informative insights for researchers looking to maximize research impact. OBJECTIVES: We analyzed publications related to pancreatic surgery primarily focused on pancreatic and periampullary tumors to identify elements associated with acceptance into high impact journals and a high likelihood of future citations. METHODS: A comprehensive review of nine surgical journals was performed between 2010 and 2019. Journals were grouped based on impact factor into high (>3), medium (1‐3), and low (<1) impact categories. Each publication was annotated to identify study topic, methodology, and statistical approach. Findings were compared according to journal impact and number of citations to identify predictors of success across these 2 domains. RESULTS: A total of 1044 out of 21,536 (4.8%) articles published in the index journals were related to pancreatic tumors. The most common focus of study was perioperative outcomes and complications (46.7%). There was significantly more number of authors, participating institutions, countries, and randomized clinical trials in higher impact journals as well as high‐cited articles (P < 0.05). Although advanced statistical analysis was used more commonly in high‐impact journals (P < 0.05), it did not translate to higher citations (P > 0.05). CONCLUSIONS: Pancreatic neoplasia continues to be extensively studied in surgical literature. Specific elements of study methodology and design were identified as potentially key attributes to acceptance in high impact journals and citation success. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02231066/full - - -Record #24 of 151 -ID: CN-02664168 -AU: Song Y -AU: Shen L -AU: Fu Y -AU: Li B -AU: Sun J -AU: Sun S -AU: Sun J -AU: Li B -AU: Yu H -AU: Ni Y -AU: et al. -TI: Visual analysis on clinical randomized controlled trial of fire needle based on VOSviewer and CiteSpace -SO: Zhongguo zhen jiu [Chinese acupuncture & moxibustion] -YR: 2024 -VL: 44 -NO: 2 -PG: 231‐238 -PM: PUBMED 38373773 -PT: Journal article -KY: *Acupuncture Therapy [methods]; *Herpes Zoster; Bibliometrics; Bloodletting; Humans; Needles -DOI: 10.13703/j.0255-2930.20230321-0004 -AB: To analyze the research hotspots, frontiers and trends of fire needle clinical randomized controlled trial (RCT) literature in the past 10 years by using bibliometrics and knowledge mapping methods. Six Chinese and English databases including CNKI, Wanfang, VIP, SinoMed, PubMed and Web of Science ( WOS ) were searched for RCT research literature on fire needle. CiteSpace V6.1.R6 and VOSviewer V1.6.18 software were used to analyze the cooperation network, keyword co‐occurrence, keyword clustering, keyword timeline, keyword emergence, etc., and to draw a visual knowledge map. A total of 1 973 Chinese articles and 3 English articles were included. The top three institutions that publish articles were Guangzhou University of CM, Heilongjiang University of CM and Beijing Hospital of TCM Affiliated to Capital Medical University. The fire needle was often combined with acupuncture, cupping and bloodletting therapy in the treatment of acne, vitiligo, lumbar disc herniation, herpes zoster, stroke sequelae, facial paralysis, knee osteoarthritis and so on. The research frontiers included the combined application of fire needle and other therapies, clinical mechanism research and efficacy evaluation index research. In the future, we should expand the dominant diseases, optimize the research design, strengthen the cooperation between the teams, and carry out high‐level clinical research. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02664168/full - - -Record #25 of 151 -ID: CN-02658358 -AU: Zhang W -AU: Li M -AU: Li X -AU: Wang X -AU: Liu Y -AU: Yang J -TI: Global trends and research status in ankylosing spondylitis clinical trials: a bibliometric analysis of the last 20 years -SO: Frontiers in immunology -YR: 2023 -VL: 14 -PG: 1328439 -PM: PUBMED 38288126 -PT: Journal article -KY: *Arthritis, Rheumatoid; *Autoimmune Diseases; *Spondylitis, Ankylosing [therapy]; Bibliometrics; Etanercept; Humans -DOI: 10.3389/fimmu.2023.1328439 -AB: BACKGROUND: Ankylosing spondylitis (AS) is a rheumatic and autoimmune disease associated with a chronic inflammatory response, mainly characterized by pain, stiffness, or limited mobility of the spine and sacroiliac joints. Severe symptoms can lead to joint deformity, destruction, and even lifelong disability, causing a serious burden on families and society as a whole. A large number of clinical studies have been published on AS over the past 20 years. This study aimed to summarize the current research status and global trends relating to AS clinical trials through a bibliometric analysis. METHODS: The Web of Science Core Collection database was searched for publications related to AS clinical trials published between January 2003 and June 2023. Bibliometric analysis and web visualization were performed using CiteSpace, VOSviewer, and a bibliometric online analysis platform (https://bibliometric.com), which included the number of publications, citations, countries, institutions, journals, authors, references, and keywords. RESULTS: 1,212 articles published in 201 journals from 65 countries were included in this study. The number of publications related to AS clinical trials is increasing annually. The United States and the Free University of Berlin, the countries and institutions, respectively, that have published the most articles on AS, have made outstanding contributions to this field. The author with the most published papers and co‐citations over the period covered by the study was Desiree Van Der Heijde. The journal with the most published and cited articles was Annals of the Rheumatic Diseases. The keywords: "double‐blind," "rheumatoid arthritis," "efficacy," "placebo‐controlled trial," "infliximab," "etanercept," "psoriatic arthritis" and "therapy" represent the current research hotspots regarding AS. DISCUSSION: This is the first study to perform a bibliometric analysis and visualization of AS clinical trial publications, providing a reliable research focus and direction for clinicians. Future studies in the field of AS clinical trials should focus on placebo‐controlled trials of targeted therapeutic drugs. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02658358/full - - -Record #26 of 151 -ID: CN-01939586 -AU: Kim KS -AU: Chung JH -AU: Lee SW -TI: Randomized controlled trials on erectile dysfunction: quality assessment and relevant clinical impact (2007-2018) -SO: International journal of impotence research -YR: 2020 -VL: 32 -NO: 2 -PG: 213‐220 -PM: PUBMED 31024112 -XR: EMBASE 627449331 -PT: Journal article -KY: *Bibliometrics; *erectile dysfunction; *quality control; Article; Cochrane Library; Cochrane assessment; Data quality assessment; Erectile Dysfunction [*therapy]; Exercise; Human; Humans; Jadad scale; Male; Outcome assessment; Priority journal; Quality assessment tool; Questionnaire; Randomized Controlled Trials as Topic [*standards]; Randomized controlled trial (topic); Van Tulder scale -DOI: 10.1038/s41443-019-0143-x -AB: The aim of this study was to assess the quality of randomized controlled trials (RCTs) on erectile dysfunction (ED) conducted from 2007 to 2018. We searched for RCT original articles on ED published between 2007 and 2018 using PubMed, Embase, and Cochrane Library databases. RCT quality assessment was performed using Jadad scale, van Tulder scale, and Cochrane Collaboration’s Risk of Bias Tool. The effects on RCT quality of including treatment methods, funding sources, institutional review board (IRB) approval statements, and intervention description to the studies were assessed. Blinding and allocation concealment were described in 67.9 and 8.7% of the RCTs, respectively. Blinding tended to decrease, but a sharp rise in blinding was observed in 2011–2012 and allocation in 2017–2018. Funding statement inclusion (60.3% overall) and intervention description (96.4% overall) tended to increase steadily. IRB statement inclusion (78.3% overall) increased (p = 0.05). Jadad scores rose significantly until 2011–2012 but decreased thereafter except 2017–2018 (p = 0.09). RCTs with funding statements had higher Jadad and van Tulder scores than unfunded RCTs (p < 0.01 and 0.02, respectively). Quality improvement has observed from 2007 to 2012 and 2017 to 2018 with Jadad scale because of increased funding, multicenter studies, and intervention description. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01939586/full - - -Record #27 of 151 -ID: CN-01772968 -AU: Rigby K -AU: Silagy C -AU: Crockett A -TI: Health economic reviews. Are they compiled systematically? -SO: International journal of technology assessment in health care -YR: 1996 -VL: 12 -NO: 3 -PG: 450‐459 -PM: PUBMED 8840665 -XR: EMBASE 26295787 -PT: Journal article -KY: *Bibliometrics; *Cost‐Benefit Analysis; *Review Literature as Topic; *health economics; Clinical trial; Controlled clinical trial; Cost effectiveness analysis; Data base; Decision making; Health care need; Medical research; Randomized controlled trial; Review -AB: Attempts to perform economic reviews of randomized controlled trials frequently lack a systematic approach. This conclusion is consistent with the findings of previous analyses of review articles in other fields, which have highlighted the failure to apply the same degree of rigor to this type of research synthesis that the scientific community has come to expect from primary research articles. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01772968/full - - -Record #28 of 151 -ID: CN-02414944 -AU: Peres MF -AU: Braschinsky M -AU: May A -TI: Effect of Altmetric score on manuscript citations: a randomized-controlled trial -SO: Cephalalgia -YR: 2022 -VL: 42 -NO: 13 -PG: 1317‐1322 -PM: PUBMED 35702033 -XR: EMBASE 2017932278 -PT: Journal article -KY: *headache; *social media; Article; Bibliometrics; Controlled study; Cost benefit analysis; Diffusion; Human; Humans; Journal Impact Factor; Metric system; Outcome assessment; Randomized controlled trial; Social Media; Social Networking -DOI: 10.1177/03331024221107385 -AB: BACKGROUND: Alternative metrics to traditional, citation‐based metrics are increasingly being used. These are complementary to traditional metrics, like downloads and citations, and give information on how often a given journal article is discussed and used in professional (reference managers) and social networks, such as mainstream media and Twitter. Altmetrics is used in most journals and is available in all indexed headache medicine journals. Whether Altmetrics have an input on traditional, citation‐based metrics or whether it is a stand‐alone metric system is not clear. Actively promoting a paper through media channels will probably increase the Altmetric score but the question arises whether this will also increase citations and downloads of this individual paper. METHODS: Focusing on this point we performed a randomized study in order to test the hypothesis that a promotion intervention would improve citations and other science metric scores. We selected 48 papers published in Cephalalgia from July 2019 to January 2020 and randomized them to either receive an active promotion through social media channels or not. The primary outcome used was the difference between mean article citations with versus without intervention 12 months after the intervention period. RESULTS: The results show that the alternative metrics significantly increased for those papers randomly selected to receive an intervention compared to those who did not. This effect was observed in the first 12 months, right after the boosting strategy was performed. The higher promoted paper diffusion in social media lead to a significantly higher number of citations and downloads. CONCLUSION: Further promotion strategies should be studied in order to tailor the best cost‐benefit intervention. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02414944/full - - -Record #29 of 151 -ID: CN-01997775 -AU: Maggio LA -AU: Leroux TC -AU: Artino AR -TI: To tweet or not to tweet, that is the question: a randomized trial of Twitter effects in medical education -SO: PloS one -YR: 2019 -VL: 14 -NO: 10 -PG: e0223992 -PM: PUBMED 31618267 -XR: EMBASE 2003397185 -PT: Journal article -KY: *medical education; Article; Bibliometrics; Biomedical Research; Controlled study; Education, Medical [*methods]; Human; Human experiment; Humans; Major clinical study; Outcome assessment; Randomized controlled trial; Social Media -DOI: 10.1371/journal.pone.0223992 -AB: Introduction Many medical education journals use Twitter to garner attention for their articles. The purpose of this study was to test the effects of tweeting on article page views and downloads. Methods The authors conducted a randomized trial using Academic Medicine articles published in 2015. Beginning in February through May 2018, one article per day was randomly assigned to a Twitter (case) or control group. Daily, an individual tweet was generated for each article in the Twitter group that included the title, #MedEd, and a link to the article. The link delivered users to the article's landing page, which included immediate access to the HTML full text and a PDF link. The authors extracted HTML page views and PDF downloads from the publisher. To assess differences in page views and downloads between cases and controls, a time‐centered approach was used, with outcomes measured at 1, 7, and 30 days. Results In total, 189 articles (94 cases, 95 controls) were analyzed. After days 1 and 7, there were no statistically significant differences between cases and controls on any metric. On day 30, HTML page views exhibited a 63% increase for cases (M = 14.72, SD = 63.68) when compared to controls (M = 9.01, SD = 14.34; incident rate ratio = 1.63, p = 0.01). There were no differences between cases and controls for PDF downloads on day 30. Discussion Contrary to the authors' hypothesis, only one statistically significant difference in page views between the Twitter and control groups was found. These findings provide preliminary evidence that after 30 days a tweet can have a small positive effect on article page views. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01997775/full - - -Record #30 of 151 -ID: CN-01760251 -AU: Okamoto S -AU: Rahman M -AU: Fukui T -TI: Japan's contribution to clinical pediatrics research in the last decade -SO: Pediatrics international -YR: 2004 -VL: 46 -NO: 1 -PG: 1‐4 -PM: PUBMED 15043655 -XR: EMBASE 38333620 -PT: Journal article -KY: *clinical research; *pediatrics; Article; Bibliometrics; Child; Clinical trial; Cohort analysis; Controlled clinical trial; Controlled study; Data base; Human; Humans; Japan; MEDLINE; Medline; Pediatrics; Priority journal; Randomized controlled trial; Research [*statistics & numerical data]; Statistical significance; Statistics, Nonparametric -DOI: 10.1111/j.1328-0867.2004.01836.x -AB: Objective: To determine Japan's contribution to research in clinical pediatrics over the last decade. Methods: Articles published in highly reputable pediatrics journals from 1991‐2000 were accessed through the MEDLINE database. The number of articles which had an affiliation with a Japanese institution were counted for each of the journals and also summed in total. Proportions of randomized controlled trials (RCTs) and case‐control/cohort studies among the articles from Japan were also generated and compared with the average for the entirety. In addition, shares of the top‐ranking countries were presented along with their trend over time. Results: In total, 20 189 articles were published in the selected seven pediatric journals from 1991‐2000. Japan contributed 3.0% of these articles and this contribution was ranked 7th in the world. A negative trend was noticed in Japan's contribution over time but it was not statistically significant (z = ‐0.40, P = 0.16). RCTs accounted for 7. 3% of the total articles, but only 0.34% of those from Japan. Conclusions: Japan's share of articles in pediatrics research was smaller than that in basic science and some of the other clinical fields. The number of articles from Japan providing a high level of evidence was meager in this field. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01760251/full - - -Record #31 of 151 -ID: CN-02074729 -AU: Valderrama P -AU: Valderrama A -AU: Baca P -TI: Bibliometric analysis and evaluation of the journal Medicina Oral Patología Oral y Cirugía Bucal (2008-2018) -SO: Medicina oral, patologia oral y cirugia bucal -YR: 2020 -VL: 25 -NO: 2 -PG: e180‐e187 -PM: PUBMED 31893475 -XR: EMBASE 630497869 -PT: Journal article -KY: *Bibliometrics; *Oral Surgical Procedures; Adult; Article; Controlled study; Female; Funding; Gender; Journal Impact Factor; Journal impact factor; Major clinical study; Male; Oral surgery; Randomized controlled trial; Spain; Stomatology; Web of Science -DOI: 10.4317/medoral.23289 -AB: BACKGROUND: In 2008 the journal Medicina Oral Patología Oral y Cirugía Bucal was included in Journal Citation Reports. To appraise its evolution and current status, this study carried out a bibliometric analysis and evaluation of the journal for the period 2008‐2018. MATERIAL AND METHODS: From the Web of Science, Journal Citation Reports we obtained the indicators Journal Impact Factor (JIF), 5‐year JIF, JIF without self‐cites, Eigenfactor score and Article Influence score (2010‐2017); and from the Core Collection database the following variables: number and article types, institutions and countries of origin of the authors (2008‐2018), and the variable cited and citing journal data in 2017. Twelve articles/year (n=132) were randomly selected to gather: the time between submittal and acceptance of an article, number of authors/article, representation of each section, gender of first author, and funding. RESULTS: The journal occupied the third quartile of the JCR from 2010 to 2017, when it moved up to the second quartile. From 2008 to 2018 it published a total of 1,518 documents, 90% articles and 9.5% reviews. Sixty countries were represented, 48.68% of the documents coming from Spain, and overall 1,293 institutions were involved. Between submittal and acceptance of articles, the average time was 134.42 days, without differences between years. The mean of authors/article was 5.15, increasing over time. The sections most represented were Oral Medicine and Pathology, and Oral Surgery. There were no differences regarding the gender of the first author, and in general the authors did not provide information about funding received. CONCLUSIONS: The bibliometric results indicate a steadily improving position of this journal, along with a tendency to reduce self‐citation. The time between reception of an article and its acceptance was very stable, the number of authors per article showed an increase, and there was a nearly equal representation of males and females as the first author. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02074729/full - - -Record #32 of 151 -ID: CN-02494577 -AU: Amirguliyev S -AU: Zhang P -AU: Al-Karagholi MA -AU: Do TP -TI: Letter to the Editor regarding "Effect of Altmetric score on manuscript citations: a randomized-controlled trial" -SO: Cephalalgia -YR: 2022 -VL: 42 -NO: 13 -PG: 1436‐1442 -PM: PUBMED 35929061 -PT: Journal article -KY: *Bibliometrics; *Social Media; Humans; Randomized Controlled Trials as Topic -DOI: 10.1177/03331024221118925 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02494577/full - - -Record #33 of 151 -ID: CN-02324691 -AU: Mejia CR -AU: Valladares-Garrido MJ -AU: Oyarce-Calderon A -AU: Nina AN -AU: Castillo-Mejia R -TI: Precarious scientific publication amongst Peruvian medical specialists: analysis of results in Google Academics and Scopus -SO: Acta medica peruana -YR: 2021 -VL: 38 -NO: 2 -PG: 110‐116 -XR: EMBASE 2014749471 -PT: Journal article -KY: *Scopus; *bibliometrics; *medical specialist; *physician; Article; Controlled study; Dermatology; Gastroenterology; Human; Neurology; Publishing; Randomized controlled trial -DOI: 10.35663/AMP.2021.382.1934 -AB: Introduction: In industrialized countries there is large production of publications from specialized physicians on specific topics regarding their working areas. Reality is quite different in Peru. Objective: To determine the rates of scientific paper production found in Google Academics and Scopus, as well as their association with medical specialties. Methodology: This is an analytical cross‐section study. Randomized sampling of medical specialists registered in the Peruvian College of Physicians was performed. Those who were selected were searched aiming to determine whether they had produced papers in publications that would be found in Google Academics or that would be indexed in the Scopus database. Their lifetime production was reported, together with statistical associations. Results: Out of 2108 specialized physicians, 1810 (85.9%) and 2027 (96.2%) had never produced any scientific publication that could have been found in Google Academics or in Scopus indexed journals, respectively. Specialties most frequently found in Google Academics were as follows: gastroenterology (46.3%), dermatology (44.4%), and neurology (42.5%). In Scopus, most frequently found specialties were neurology (15.0%), gastroenterology and dermatology (11.1%, both), and pathology (10.9%). The highest number of production in foreign Scopus‐indexed publications was 4 original papers for a corresponding author. There were statistically significant associations with respect to the lowest numbers of Scopus‐indexed publications for 15 specialties (p<0.042 for all), and thirteen of them featured no scientific production at all. Conclusions: The low number of authors who published scientific papers was surprising, and this may serve as an alert about the low resources available for generating and publishing their research, so strategies for helping in this purpose should be established. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02324691/full - - -Record #34 of 151 -ID: CN-01778515 -AU: Nieri M -AU: Saletta D -AU: Buti J -AU: Pagliaro U -AU: Guidi L -AU: Rotundo R -AU: Prato GP -TI: From initial case report to randomized clinical trial through 20 years of research in periodontal therapy -SO: Journal of clinical periodontology -YR: 2009 -VL: 36 -NO: 1 -PG: 39‐43 -PM: PUBMED 19021788 -XR: EMBASE 354090754 -PT: Journal article -KY: *bibliometrics; *dental research; *outcome assessment; *periodontal disease /therapy; *randomized controlled trial; Article; Bibliometrics; Dental Research [*methods]; Human; Humans; Methodology; Outcome Assessment, Health Care [*methods]; Periodontal Diseases [*therapy]; Randomized Controlled Trials as Topic; Validation Studies as Topic; Validation study -DOI: 10.1111/j.1600-051X.2008.01341.x -AB: AIM: Case reports (CRs) are often the first publication of a new treatment, but randomized clinical trials (RCTs) are needed to confirm the data. The aim of this study was to evaluate how many therapies published as CRs were followed by RCTs of these therapies over a 20‐year period. MATERIAL AND METHODS: Two researchers conducted a search through international periodontal journals and found the CRs on periodontal treatments published from 1984 to 1986. Subsequent electronic searches made it possible to verify how many of the treatments published as CRs were also investigated through RCTs over the following 20 years. RESULTS: Thirty‐one different therapies were selected out of the 33 published CRs; 15 (48%) of these 31 treatments were investigated by RCTs over the next 20 years. CONCLUSIONS: As 52% of the CRs were not validated by RCTs, practitioners should view their results with caution. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01778515/full - - -Record #35 of 151 -ID: CN-01708884 -AU: Smith BA -AU: Lee HJ -AU: Lee JH -AU: Choi M -AU: Jones DE -AU: Bausell RB -AU: Broome ME -TI: Quality of reporting Randomized Controlled Trials (RCTs) in the nursing literature: application of the Consolidated Standards of Reporting Trials (CONSORT) -SO: Nursing outlook -YR: 2008 -VL: 56 -NO: 1 -PG: 31‐37 -PM: PUBMED 18237622 -XR: EMBASE 351139860 -PT: Journal article -KY: *nursing research; *publication; *publishing; *randomized controlled trial; Analysis of Variance; Analysis of variance; Article; Bibliometrics; Human; Humans; Nursing Research [*standards]; Periodicals as Topic [*standards]; Publishing [*standards]; Quality Control; Quality control; Randomized Controlled Trials as Topic [*standards]; Standard -DOI: 10.1016/j.outlook.2007.09.002 -AB: In the era of evidence‐based practice (EBP), Randomized Controlled Trials (RCTs) may provide the best evidence of the efficacy of nursing interventions and yet the quality of RCT reporting in nursing literature has not been evaluated. The purposes of this study were to apply the Consolidated Standards of Reporting Trials (CONSORT) statement to published reports of nursing science, examine how adequately the published reports adhere to the statement, and examine the effect of the adoption of CONSORT on the quality of the RCT published reports. One hundred RCTs from 2002‐2005 were identified from 4 nursing journals. Articles were randomly assigned to 4 reviewers and the quality of the published reports was evaluated using a modified CONSORT checklist. There was no difference between the 4 journals in the quality of the published reports of RCTs based on the modified CONSORT checklist employed (F = 1.27, P =.29). The quality of reporting of RCTs improved significantly in the only journal, Nursing Research, to adopt the CONSORT statement during the study period (t =‐2.70, P =.01). Adoption of CONSORT is recommended as it may lead to an overall improvement in quality of reporting of RCTs in nursing journals. The profession may also wish to explore the use or development of standards similar to CONSORT but ones more appropriate for the types of research typical of that published by nurse scientists. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01708884/full - - -Record #36 of 151 -ID: CN-01755760 -AU: Yu GP -AU: Gao SW -TI: Quality of clinical trials of Chinese herbal drugs, a review of 314 published papers -SO: Zhongguo zhong xi yi jie he za zhi zhongguo zhongxiyi jiehe zazhi = chinese journal of integrated traditional and western medicine -YR: 1994 -VL: 14 -NO: 1 -CC: Complementary Medicine -PG: 50‐52 -PM: PUBMED 8044004 -XR: EMBASE 24919810 -PT: Journal article -KY: *clinical trial; *randomized controlled trial; Bibliometrics; China; Clinical Trials as Topic; Controlled clinical trial; Drugs, Chinese Herbal [therapeutic use]; Human; Humans; Periodicals as Topic; Publication; Quality Control; Quality control; Randomized Controlled Trials as Topic; Review -AB: The study was based on a review of clinical trials for herbal drugs published in various journals. Three journals selected were Chinese Journal of Integrated Traditional and Western Medicine (JITWM), Journal of Traditional Chinese Medicine (JTCM), and a provincial Journal of Traditional Medicine (JTM). In order to reflect different levels of the journal, each paper of the clinical trials of herbal drugs in the above‐mentioned journals during the survey years, 1991, 1987 and 1980 (or 1981) was reviewed using a standard checklist and quantified through a score system. A total of 314 paper were reviewed, in which 179 in 1991, 82 in 1987, and 53 in 1980 and 1981. Controlled trials were found in 86% of JITWM, 40.8% of JTCM, and 26.8% of JTM in 1991. Although there was an increased trend in the use or randomized trials, it still showed a lower proportion, respectively 52.9% in JITWM, 36.0% in JTCM, and 11.1% in JTM. We found that the quality of clinical trials in JITWM was the first, JTCM the second, JTM the third and showed a gradually improved trend with time. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01755760/full - - -Record #37 of 151 -ID: CN-01752788 -AU: Kaido T -TI: Analysis of randomized controlled trials on hepatopancreatic surgery -SO: Digestive diseases and sciences -YR: 2006 -VL: 51 -NO: 10 -PG: 1761‐1766 -PM: PUBMED 16957997 -XR: EMBASE 46234955 -PT: Journal article -KY: *bibliometrics; *liver resection; *pancreatectomy; *randomized controlled trial; Bibliometrics; Clinical trial; Controlled clinical trial; Hepatectomy [*statistics & numerical data]; Human; Humans; Pancreatectomy [*statistics & numerical data]; Randomized Controlled Trials as Topic [*statistics & numerical data]; Review; Statistics -DOI: 10.1007/s10620-006-9219-9 -AB: The randomized controlled trial (RCT) is an important research method, providing the highest evidence and playing a pivotal role in the performance of evidence‐based medicine. However, RCTs on hepatopancreatic surgery have been performed less frequently than RCTs in other fields. Therefore, this review analyzes the characteristics of RCTs on hepatic and pancreatic surgery to propose a breakthrough. We retrieved studies performed via a MEDLINE search to identify prospective RCTs on hepatopancreatic surgery in the last decade. Eligible RCTs were analyzed using the following items: study design, publication year, geographical area, sample size, multicenter study, and impact factor. Studies comparing surgical technique or methods have composed the majority of the RCTs involving hepatectomy and pancreatectomy. About half of the RCTs on hepatectomy have been performed in East Asia, whereas most of the RCTs on pancreatectomy were undertaken in Western countries. The average sample number of RCT on hepatectomy is significantly smaller than those in other fields. Moreover, multicenter studies are less frequently performed on hepatectomy compared with pancreatectomy. Promoting the organization of multicenter studies would be the best way to increase the number and sample size of RCTs on hepatectomy. Adequate RCTs observing the Consolidated Standards of Reporting Trials statements are necessary to obtain reliable evidence. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01752788/full - - -Record #38 of 151 -ID: CN-01724005 -AU: Miyaki K -TI: Genetic polymorphisms in homocysteine metabolism and response to folate intake: a comprehensive strategy to elucidate useful genetic information -SO: Journal of epidemiology -YR: 2010 -VL: 20 -NO: 4 -PG: 266‐270 -PM: PUBMED 20571252 -XR: EMBASE 359229744 -PT: Journal article -KY: *genetic association; *single nucleotide polymorphism; Bibliometrics; Blood; Folic Acid [*administration & dosage]; Genetic Association Studies; Genetics; Genome‐Wide Association Study; Homocysteine [blood, *metabolism]; Human; Humans; Meta analysis; Metabolism; Meta‐Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2) [*genetics]; Polymorphism, Single Nucleotide; Randomized Controlled Trials as Topic; Randomized controlled trial; Review -DOI: 10.2188/jea.JE20100042 -AB: Homocysteine is a risk factor for atherosclerosis, and the level of homocysteine in plasma is known to be strongly influenced by genetic factors‐not only rare variants, but also common polymorphisms. This report describes a comprehensive postgenomic strategy for elucidating useful genetic information about homocysteine metabolism. The standard method for gathering such information is the candidate gene approach, which is an effective method based on known biological information. After collecting evidence from independent research projects, a critical epidemiological review permits a determination as to whether a putative association is true or not. A genome‐wide association study (GWAS), which requires no biological information, can identify new candidates and confirm associations suggested by the candidate gene approach. The importance of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, which was shown in a randomized controlled trial conducted by the present author, and in other studies, was independently confirmed by a large‐scale GWAS. GWASs have also identified new candidate genes, but these must be confirmed by independent studies. In homocysteine metabolism, the classical candidate gene approach was sufficiently robust to detect the true association. However, candidate markers newly discovered by GWAS need to be confirmed by well‐designed epidemiological studies to determine their significance. International statements, such as CONSORT and STREGA, provide useful principles for conducting such research. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01724005/full - - -Record #39 of 151 -ID: CN-01733696 -AU: Peng WN -AU: Liu ZS -AU: Deng YH -AU: Mao M -AU: Yu JN -AU: Du Y -TI: Evaluation of literature quality of acupuncture for treatment of herpes zoster and approach to the laws of treatment -SO: Zhongguo zhen jiu [Chinese acupuncture & moxibustion] -YR: 2008 -VL: 28 -NO: 2 -CC: Complementary Medicine -PG: 147‐150 -PM: PUBMED 18405162 -XR: EMBASE 351604008 -PT: Journal article -KY: *acupuncture; *bibliometrics; *herpes zoster /diagnosis /therapy; Acupuncture Therapy; Bibliometrics; Follow up; Follow‐Up Studies; Herpes Zoster [diagnosis, *therapy]; Human; Humans; Randomized Controlled Trials as Topic; Randomized controlled trial; Review -AB: OBJECTIVE: To assess the quality of literature of clinical studies on acupuncture in treatment of herpes zoster. METHODS: The literatures between 1994‐2006 were searched by means of electronic retrieval. Type and methodology, general condition, diagnosis of diseases and enrolled and excluded criteria, assessment of sample content, treatment condition, criteria for assessment of therapeutic effects, following‐up, etc. in clinical studies are evaluated according to principles and methods of clinical epidemiology and evidence‐based medicine. RESULTS: Of the 399 literatures enrolled, only 8 were authentic randomized controlled trials (RCTs), 20 quasi‐randomized controlled trials, 66 non‐randomized concurrent controlled trials and 277 narrative studies, 70 had clear diagnostic criteria, 16 mentioned enrolled or excluded criteria, 287 had clear criteria for therapeutic effects, 107 reported follow‐up, 2 had the description of health economical index, 9 reported adverse reaction. CONCLUSION: At present, correct randomization, concealment, blinding and placebo‐control, and the RCTs with generally accepted criteria for assessment of diagnosis and therapeutic effects, safety evaluation and rational design of follow‐up are needed. It is indicated by preliminary study of the literatures that blood‐letting puncture and cupping at Ashi points are main methods for treatment of herpes zoster. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01733696/full - - -Record #40 of 151 -ID: CN-01784882 -AU: Wang C -AU: He WJ -AU: Guo Y -TI: Analysis on acupuncture related articles published in periodicals in science citation index (SCI) in 2008 -SO: Zhongguo zhen jiu [Chinese acupuncture & moxibustion] -YR: 2010 -VL: 30 -NO: 9 -CC: Complementary Medicine -PG: 755‐758 -PM: PUBMED 20886797 -XR: EMBASE 359808015 -PT: Journal article -KY: *acupuncture; *bibliometrics; *publication; *science; Acupuncture Therapy [*statistics & numerical data]; Article; Bibliometrics; Journal Impact Factor; Journal impact factor; Periodicals as Topic [*statistics & numerical data]; Randomized Controlled Trials as Topic; Randomized controlled trial; Science [*statistics & numerical data]; Statistics -AB: Acupuncture related articles published in periodicals in Science Citation Index (SCI) in 2008 were summarized and analyzed. About 583 articles were collected using "acupuncture" and "in 2008" as keywords in the Web of Science data base by information retrieval. These papers were summarized and analyzed from various aspects of country, language, subject category, literature type, publication sources, impact factor, research method, acupoints, disease category and needling methods by using Excel software combined with manual sorting of the literature, the aim is to provide a reference for domestic acupuncture research. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01784882/full - - -Record #41 of 151 -ID: CN-02176320 -AU: Lorenzon L -AU: Grossman RC -AU: Soreide K -TI: Impact of Randomized Controlled Trials in the Social Media: does Science Trend As Much As Everyday Events? -SO: World journal of surgery -YR: 2021 -VL: 45 -NO: 1 -PG: 88‐96 -PM: PUBMED 32892272 -XR: EMBASE 632797327 -PT: Journal article -KY: *bibliometrics; *medicine; *randomized controlled trial (topic); *social media; Bibliometrics; Human; Humans; Information Dissemination; Information dissemination; Journal Impact Factor; Journal impact factor; Medicine [statistics & numerical data]; Randomized Controlled Trials as Topic; Social Media [statistics & numerical data] -DOI: 10.1007/s00268-020-05769-8 -AB: BACKGROUND: The approach to the scientific literature is evolving. Currently, dissemination of articles happens in real time through social media (SoMe) channels, and little is known about its impact in medicine. The aim of this study was to investigate if SoMe dissemination followed trends independent from articles type and content. METHODS: First, the SoMe engagement of a popular theme (#BlackFriday) and a relevant theme (#ClimateChange) was compared using a SoMe analytic tool to test if the popular theme would reach more engagement. In a second analysis, themes in colorectal surgery in the SoMe community were explored. Altmetric Explorer was searched for the term "colorectal surgery" and the outputs were categorized into 'randomized controlled trials' (RCTs) and 'other studies'. Subgroups were compared for the Altmetric scores using statistical analyses. RESULTS: The analytic tool documented that #BlackFriday outnumbered #ClimateChange in mentions and engagement (1.6 million vs 127.000 mentions). Following, Altmetric Explorer identified 1381 articles, including 92 RCTs (7.1%). Overall, 25,554 mentions were documented from 1205 outputs (97.0% by Twitter). A greater percentage of "other studies" ranked in the lower Altmetric score categories (p = 0.0007). Similarly, the median Altmetric score was higher in the RCT subgroup comparing with "other studies" (6.5 vs. 2.0, Mann‐Whitney p = 0.0001). CONCLUSIONS: In this study, RCTs represented just the 7.1% of the studies and produced 11% of Twitter outputs. The median Altmetric scores obtained by RCTs were higher than those of other studies. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02176320/full - - -Record #42 of 151 -ID: CN-02051995 -AU: Brandt JS -AU: Hadaya O -AU: Schuster M -AU: Rosen T -AU: Sauer MV -AU: Ananth CV -TI: A Bibliometric Analysis of Top-Cited Journal Articles in Obstetrics and Gynecology -SO: JAMA network open -YR: 2019 -VL: 2 -NO: 12 -PG: e1918007 -PM: PUBMED 31860106 -XR: EMBASE 630324944 -PT: Journal article -KY: *gynecology; *obstetrics; Adult; Article; Bibliometrics; Controlled study; Cross‐Sectional Studies; Endometriosis; Female; Gynecology [*statistics & numerical data]; Human; Humans; Journal Impact Factor; Obstetrics [*statistics & numerical data]; Osteoporosis; Periodicals as Topic [*statistics & numerical data]; Preeclampsia; Publishing; Randomized controlled trial; SciSearch; Writing -DOI: 10.1001/jamanetworkopen.2019.18007 -AB: Importance: Citation analysis is a bibliometric method that uses citation rates to evaluate research performance. This type of analysis can identify the articles that have shaped the modern history of obstetrics and gynecology (OBGYN). Objectives: To identify and characterize top‐cited OBGYN articles in the Institute for Scientific Information Web of Science's Science Citation Index Expanded and to compare top‐cited OBGYN articles published in specialty OBGYN journals with those published in nonspecialty journals. Design, Setting, and Participants: Cross‐sectional bibliometric analysis of top‐cited articles that were indexed in the Science Citation Index Expanded from 1980 to 2018. The Science Citation Index Expanded was queried using search terms from the American Board of Obstetrics and Gynecology's 2018 certifying examination topics list. The top 100 articles from all journals and the top 100 articles from OBGYN journals were evaluated for specific characteristics. Data were analyzed in March 2019. Main Outcomes and Measures: The articles were characterized by citation number, publication year, topic, study design, and authorship. After excluding articles that featured on both lists, top‐cited articles were compared. Results: The query identified 3767874 articles, of which 278846 (7.4%) were published in OBGYN journals. The top‐cited article was published by Rossouw and colleagues in JAMA (2002). Top‐cited articles published in nonspecialty journals were more frequently cited than those in OBGYN journals (median [interquartile range], 1738 [1490‐2077] citations vs 666 [580‐843] citations, respectively; P <.001) and were more likely to be randomized trials (25.0% vs 2.2%, respectively; difference, 22.8%; 95% CI, 13.5%‐32.2%; P <.001). Whereas articles from nonspecialty journals focused on broad topics like osteoporosis, articles from OBGYN journal focused on topics like preeclampsia and endometriosis. Conclusions and Relevance: This study found substantial differences between top‐cited OBGYN articles published in nonspecialty vs OBGYN journals. These differences may reflect the different goals of the journals, which work together to ensure optimal dissemination of impactful articles.. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02051995/full - - -Record #43 of 151 -ID: CN-01333605 -AU: Campbell MA -AU: Alter DA -TI: The extent to which music has penetrated medical research: a bibliometric review -SO: Irish journal of medical science -YR: 2017 -VL: 186 -NO: 1 -PG: S35‐S36 -XR: EMBASE 614572053 -PT: Journal article; Conference proceeding -KY: *medical research; *music therapy; Controlled clinical trial; Controlled study; Filter; Growth rate; Human; Preclinical study; Publication; Quantitative study; Randomized controlled trial; Recall; Scientist -DOI: 10.1007/s11845-016-1532-5 -AB: The growth of music in medical research in recent years has been extensive. This research has explored music processing, music therapy techniques and more. This project therefore set out to quantify the extent to which music has penetrated medical research. All biomedical publications relevant to music on GoPubMed from 1970 to 2015 were searched. 400 abstracts were chosen randomly by one researcher and manually searched by another. The inclusion criteria was adjusted until a bibliometric filter with>90% precision and recall was achieved. We measured the yearly number of music medicine publications and performed a time trends analysis of this growth. Time trends analysis was also performed for all GoPubMed publications, and publications relating to drug therapy, to compare growth rates. Finally, we investigated which journals music medicine publications appeared in over time, and how study methodologies have changed. Music medicine publications increased from 96 in 1970 to 734 in 2005 and 1595 in 2015: a 1560% increase 1970‐2015 and a 117% increase 2005‐2015. Music medicine research grew more rapidly since 1970 and 2005 than the growth of all research. While relative research interest is lower than drug therapy, music medicine research grew more rapidly since 1970 and 2005. While many music medicine publications appear in lower‐impact journals, the proportion of publications in mid‐impact journals has increased. Finally, music medicine research has shifted from pre‐clinical to more clinical and randomized control trials. These findings imply that as a society we may be beginning to accept music more in medical research and application. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01333605/full - - -Record #44 of 151 -ID: CN-02603943 -AU: Wang H -AU: Ye Q -AU: Xu W -AU: Wang J -AU: Liu J -AU: Xu X -AU: Zhang W -TI: Research trends of worldwide ophthalmologic randomized controlled trials in the 21st century: a bibliometric study -SO: Advances in ophthalmology practice and research -YR: 2023 -VL: 3 -NO: 4 -PG: 159‐170 -PM: PUBMED 37846318 -PT: Journal article -DOI: 10.1016/j.aopr.2023.07.003 -AB: BACKGROUND: Randomized controlled trials (RCTs) are often considered the gold standard and the cornerstone for clinical practice. However, bibliometric studies on worldwide RCTs of ophthalmology published in the 21st century have not been reported in detail yet. This study aims to perform a bibliometric study and visualization analysis of worldwide ophthalmologic RCTs in the 21st century. METHODS: Global ophthalmologic RCTs from 2000 to 2022 were searched in the Web of Science Core Collection. The number of publications, country/region, institution, author, journal, and research hotspots of RCTs were analyzed using HistCite, VOSviewer, CiteSpace, and Excel software. RESULTS: 2366 institutions and 90 journals from 83 countries/regions participated in the publication of 1769 global ophthalmologic RCTs, with the United States leading in the number of volumes and research field, and the Moorfields Eye Hospital contributing to the most publications. Ophthalmology received the greatest number of publications and co‐citations. Jeffrey S. Heier owned the most publications and Jost B. Jonas owned the most co‐citations. The knowledge foundations of global ophthalmologic RCTs were mainly retinopathy, glaucoma, dry eye disease (DED), and cataracts, and anti‐vascular endothelial growth factor (VEGF) therapy (ranibizumab), topical ocular hypotensive medication, laser trabeculoplasty. Anti‐VEGF therapy for age‐related macular degeneration (AMD), DME (diabetic macular edema), and DED, the use of new diagnostic tools, and myopia were the hottest research highlights. Anti‐VEGF therapy, prompt laser, triamcinolone, and verteporfin photodynamic therapy for AMD, DME, and CNV (choroidal neovascularization), DED, myopia, and open‐angle glaucoma were the research hotspots with the longest duration. The future research hotspots might be DED and the prevention and control of myopia. CONCLUSIONS: Overall, the number of global ophthalmologic RCTs in the 21st century was keeping growing, there was an imbalance between the regions and institutions, and more efforts are required to raise the quantity, quality, and global impact of high‐quality clinical evidence in developing countries/regions. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02603943/full - - -Record #45 of 151 -ID: CN-01943043 -AU: Wang M -AU: Li MC -AU: Wang JH -AU: Xin X -AU: Ren L -TI: Traditional medicine for antipsychotic drugs induced constipation: a bibliometric analysis of clinical studies -SO: Advances in integrative medicine -YR: 2019 -VL: 6 -CC: Complementary Medicine -PG: S115 -XR: EMBASE 2001763379 -PT: Journal article; Conference proceeding -KY: *Chinese medicine; *constipation; Adult; Adverse drug reaction; Auricular acupuncture; Case study; Clinical practice; Comparative effectiveness; Conference abstract; Drug safety; English (language); Female; Herbal medicine; Human; Major clinical study; Male; Medline; Patent; Pharmacokinetics; Plant leaf; Randomized controlled trial; Side effect; WanFang Database -DOI: 10.1016/j.aimed.2019.03.333 -AB: Background: Traditional medicine has a long history being used to treat constipation, and also commonly adjunct with antipsychotic drugs to improve constipation for psychopath in China. Our aim in this study was to conduct a comprehensive bibliometric analysis to get knowledge of the current situation of clinical practice and research. Methods: We included all types of clinical studies including randomized controlled trials (RCTs), clinical controlled trials (CCTs), and case series (CSs). We searched four Chinese and English language electronic databases from inception to December 06 2018, including: CNKI, VIP, Wan Fang Database, and PubMed. Results: We identified 97 studies with 11752 participants from 1991 to 2016, including: 31 CSs, 11 CCTs, 55 RCTs. The reported therapies were Chinese medicine decoction (28, 28.87%), Chinese patent medicine (26, 26.80%), single herbal medicine (15, 15.46%), ear acupuncture (6, 6.19%), body acupuncture (4, 4.12%), acupoint paste (4, 4.12%), acupuncture with tuina (3, 3.09%), Ziwu liuzhu low frequency treatment instrument (3, 3.09%), et al. The most frequent used single herbal were folium sennae (10 studies, dosage from 1.5 to 500 g), the most common used Chinese patent medicine were “An shen jian pi tang jiang” (5 studies). The frequent used acupoint stimulation were Tianshu (13 studies), Shangjuxu (10 studies), Zusanli (7 studies), Shenjue (4studies). No studies reported serious adverse events. Conclusions: Traditional medicine has been substantially studied and used in relieving antipsychotic drugs induced constipation, but more clinical trials are required to evaluate its effectiveness and safety, to provide evidence for its clinical application. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01943043/full - - -Record #46 of 151 -ID: CN-01759967 -AU: Zhou F -AU: Liu J -TI: Characteristics of clinical studies of summer acupoint herbal patching: a bibliometric analysis -SO: Journal of alternative and complementary medicine (New York, N.Y.) -YR: 2016 -VL: 22 -NO: 6 -CC: Complementary Medicine -PG: A134 -XR: EMBASE 611808055 -PT: Journal article; Conference proceeding -KY: *summer; Adolescent; Adult; Aged; Allergic rhinitis; Asthma; Case study; Child; China; Chinese medicine; Chronic obstructive lung disease; Clinical trial; Controlled clinical trial; Controlled study; Cross‐sectional study; Data base; Human; Major clinical study; Randomized controlled trial; Respiratory tract infection; Western medicine -DOI: 10.1089/acm.2016.29003.abstracts -AB: Purpose: Summer acupoint herbal patching (SAHP) has been widely used in China for thousands of years. This bibliometric analysis aims to provide a comprehensive review of the characteristics of clinical studies on SAHP for any condition. Methods: We included clinical studies such as randomized clinical trials (RCTs), controlled clinical studies (CCTs), case series (CSs), case reports (CRs), and cross‐sectional studies on SAHP for any condition. Six databases were searched from date of inception to March 2015. Bibliometric information and study details such as study type, characteristics of participants, details of the intervention and comparison, and outcome were extracted and analyzed. Results: A total of 937 clinical studies were identified and which were published between 1977 and 2015. This included 404 RCTs, 52 CCTs, 458 CSs, 19 CRs and 4 cross‐sectional studies and involved 232,138 participants aged 2 to 90 years from two countries. Almost all studies were from China (936, 99.89%). The five conditions most commonly treated by SAHP were asthma (401, 42.80%), chronic bronchitis (146, 15.58%), allergic rhinitis (117, 12.49%), chronic obstructive pulmonary disease (73, 7.79%), and recurrent respiratory tract infection (42, 4.48%). Among 502 controlled studies, the majority compared SAHP alone with different controls (16 categories, 275 comparisons). The most commonly used controls were Western medicine, placebo, traditional Chinese medicine, no treatment and non‐pharmaceutical traditional Chinese therapies. Composite outcome measures were the most frequently reported outcome (512, 69.19%). Conclusion: A substantial amount of research on SAHP has been published in China and which predominantly focuses on respiratory conditions. The findings from this study can be used to inform further research by highlighting areas of greatest impact for SAHP. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01759967/full - - -Record #47 of 151 -ID: CN-02259140 -AU: Seivright JR -AU: Thompson AM -AU: Villa NM -AU: Shi VY -AU: Hsiao JL -TI: Bibliometric Analysis of the 50 Most Cited Publications in Hidradenitis Suppurativa -SO: Skin appendage disorders -YR: 2021 -VL: 7 -NO: 3 -PG: 173‐179 -XR: EMBASE 634351109 -PT: Journal article -KY: *bibliometrics; *publication; *suppurative hidradenitis /drug therapy; Article; Comorbidity; Evidence based practice; Human; Pathogenesis; Patient care; Practice guideline; Priority journal; Randomized controlled trial (topic) -DOI: 10.1159/000513771 -AB: Background: Hidradenitis suppurativa (HS) has historically been a neglected disease. However, research in this field has grown exponentially in the past decade. Methods: The top‐cited HS articles from 1950 to 2020 were analyzed for authorship, study topic, study design, and senior author country of origin. Results: We found that nearly half of the top 50 cited articles were published in the last decade, with a recent increase in the number of highly cited randomized controlled trials. Medical treatment is the most cited topic, with more attention on biologics over time. The past decade has seen an increase in highly cited articles on HS comorbidities, pathogenesis, and clinical practice guidelines. There has been a predominance of highly cited HS research from Europe; highly cited studies from Africa, Asia, Australia, and South America are lacking. Conclusions: Recent advances in HS research have focused on investigating HS pathogenesis and drug development, highlighting disease comorbidities, and improving evidence‐based care. Studies in pathogenesis have translated into a paradigm shift in medical treatment from antibiotics to incorporation of targeted therapies in recent years. Encouraging growth of HS research in countries outside of North America and Europe may help to optimize HS care globally. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02259140/full - - -Record #48 of 151 -ID: CN-02333811 -AU: Dorgham A -AU: García F -AU: Serrano S -AU: Gómez MA -AU: Ruíz -TI: A bibliometric analysis of the EU research in the respiratory system beween 1987-1998 -SO: Archivos de bronconeumología -YR: 2001 -VL: 37 -NO: Suppl 1 -CC: Cochrane Iberoamerica -PG: 49 -PT: Journal article -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02333811/full - - -Record #49 of 151 -ID: CN-02195057 -AU: Wilson M -AU: Sampson M -AU: Doja A -TI: A bibliometric analysis of publication patterns of neurology articles in general medicine journals -SO: Neurology -YR: 2020 -VL: 94 -NO: 15 -XR: EMBASE 633066858 -PT: Journal article; Conference proceeding -KY: *general practice; *neurology; Conference abstract; Controlled study; Endocrine disease; Endocrinology; Gastroenterology; Gastrointestinal disease; Human; Immunology; Immunopathology; Medical Subject Headings; Medical literature; Medical society; Medline; Neurologic disease; Randomized controlled trial; Respiratory tract disease; United States -AB: Objective: To examine the publication patterns of neurology articles in general medicine (GM) journals. Background: Researchers in neurology have many options in selecting where to publish peerreviewed articles. A significant portion of neurology literature is published in GM journals. Despite this, the precise publication patterns of neurology articles in these journals has yet be examined. We therefore assessed the publication patterns of neurology articles in GM journals over a 10‐year period using a bibliometric approach. Design/Methods: The top 5 general medicine journals were identified using the 2017 Journal Citations Report (JCR) by Clarivate Analytics. We selected 4 other medical subspecialties for comparison of publication patterns with neurology: immunology, endocrinology, gastroenterology, and respirology. Using Ovid MEDLINE, we searched the 5 journals for articles published between April 2009 and April 2019 that were indexed with the following MeSH terms: nervous system diseases, immune system diseases, endocrine system diseases, gastrointestinal diseases, and respiratory tract diseases. Results: The GM journals with the 5 highest impact factors were: New England Journal of Medicine (NEJM) (79.3), Lancet (53.3), Journal of the American Medical Association (JAMA) (47.7), British Medical Journal (BMJ) (23.6), and Public Library of Science Medicine (PLOS Medicine) (11.7). Our bibliometric search yielded 3719 publications, of which 1098 were in neurology. Of these 1098 neurology publications, 317 were published in NEJM, 205 in the Lancet, 284 in JAMA, 214 in BMJ, and 78 in PLOS Medicine. Randomized controlled trials were the most frequent neurology study type in GM journals. The number of publications in each of the other specialties was: immunology (817), endocrinology (633), gastroenterology (353), and respirology (818). Conclusions: Our results provide some guidance to authors regarding where they may wish to consider submitting their neurology research. Neurology‐based articles are published more frequently in GM journals than other specialties. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02195057/full - - -Record #50 of 151 -ID: CN-02417130 -AU: Gutman SA -AU: Brown T -TI: A Bibliometric Analysis of the Quantitative Mental Health Literature in Occupational Therapy -SO: Occupational therapy in mental health -YR: 2018 -VL: 34 -NO: 4 -PG: 305‐346 -XR: CINAHL 134784699 -PT: Journal article -KY: AMED Database; Adult; Allied Health Literature; Bibliometrics; CINAHL Database; Citation Analysis; Clinical Effectiveness; Community Reintegration; Embase; Employment, Supported; Human; In Adulthood; Medical Literature; Medline; Mental Disorders; Mental Health; Occupational Therapy; Psycinfo; Social Skills; Systematic Review; Therapy -DOI: 10.1080/0164212X.2017.1413479 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02417130/full - - -Record #51 of 151 -ID: CN-02647362 -AU: Wang CY -AU: Zhou SC -AU: Li XW -AU: Li BH -AU: Zhang JJ -AU: Ge Z -AU: Zhang Q -AU: Hu JH -TI: Bibliometric analysis of randomized controlled trials of colorectal cancer over the last decade -SO: World journal of clinical cases -YR: 2020 -VL: 8 -NO: 14 -PG: 3021‐3030 -PM: PUBMED 32775383 -PT: Journal article -DOI: 10.12998/wjcc.v8.i14.3021 -AB: BACKGROUND: Colorectal cancer is one of the most common cancers globally. In China, its prevalence ranks fourth and fifth among females and males, respectively. Presently, treatment of rectal cancer follows a multidisciplinary comprehensive treatment approach involving surgery, radiotherapy, chemotherapy, and targeted therapy. With deepening theoretical and molecular research on colorectal cancer, randomized controlled trials (RCTs) on colorectal cancer have made significant progress. However, many RCTs have shortfalls. AIM: To investigate the RCTs of global colorectal cancer spanning from 2008 to 2018. To provide suggestions for conducting Chinese RCTs of colorectal cancer. METHODS: PubMed and Web of Science databases were searched to obtain RCTs of colorectal cancer carried out between January 1, 2008, and January 1, 2018. The bibliometric method was used for statistical analysis of the publication years, countries/regions, authors, institutions, source journals, quoted times, key words, and authors. RESULTS: Colorectal cancer RCTs showed an upward trend between 2008 to 2018; the top 10 research institutions in the included literature were from the United States, the United Kingdom, and other countries with a high incidence of colorectal cancer. Most of the related research journals are sponsored by European and American countries. The 15 most cited studies involved international multicenter clinical research, having few participants from Chinese research institutions. Network visualization using key words showed that RCTs on colorectal cancer focus on screening, disease‐free survival, drug treatment, surgical methods, clinical trials, quality of life, and prognosis. The result of the coauthorship network analysis showed that Chinese researchers are less involved in international exchanges compared to those from leading publication countries. CONCLUSION: High‐quality RCTs are increasingly favored by leading international journals. However, there is still a large gap in clinical research between China and leading countries. Researchers should implement standardized and accurate clinical trials, strengthen international multicenter cooperation, and emphasize quality control. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02647362/full - - -Record #52 of 151 -ID: CN-02703429 -AU: Giridharan S -AU: Kumar NV -TI: Bibliometric Analysis of Randomized Controlled Trials on Yoga Interventions for Cancer Patients: a Decade in Review -SO: Cureus -YR: 2024 -VL: 16 -NO: 4 -CC: Complementary Medicine -PG: e58993 -PM: PUBMED 38800314 -PT: Journal article -DOI: 10.7759/cureus.58993 -AB: This literature review presents a bibliometric analysis of the randomized controlled trials conducted between 2014 and 2023 on the potential benefits of yoga as a complementary therapy for cancer patients. To conduct this analysis, we searched medical and scientific databases, such as Scopus, Cochrane, and PubMed, using relevant keywords. Our search yielded 58 clinical trials involving 4,762 patients, which indicates a growing trend in this field of research. The studies we reviewed mainly focused on breast cancer patients and demonstrated the adaptability and versatility of yoga, offering a ray of hope and optimism. Among the various styles of yoga, Hatha yoga was the most frequently practiced style in these clinical trials. The analysis we conducted reveals that yoga interventions have a promising role in cancer care and can be a valuable complementary therapy for cancer patients. However, significant gaps and limitations still need to be addressed in this area of research. For instance, more rigorous and diverse investigations are needed to further establish the potential benefits of yoga interventions for cancer patients. Additionally, the standardization of yoga interventions is crucial to optimize therapeutic benefits. By addressing these gaps and limitations, we can further enhance the potential of yoga as a complementary therapy for cancer patients. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02703429/full - - -Record #53 of 151 -ID: CN-02326932 -AU: Castaldelli-Maia JM -AU: Riba MB -AU: Lecic-Tosevski D -AU: Chandra PS -AU: Cia A -AU: Tyrer PJ -AU: Heun R -AU: Szabo CP -TI: The main gaps for randomized-controlled trials in psychiatry: a bibliometric study -SO: Clinical chemistry and laboratory medicine -YR: 2020 -VL: 3 -NO: 1 -PG: 51‐63 -XR: EMBASE 2014529823 -PT: Journal article -KY: *bibliometrics; *psychiatry; *randomized controlled trial (topic); Acrophobia; Acute stress; Adjustment disorder; Adult; Agoraphobia; Alcoholism; Altitude disease; Anhedonia; Anorexia nervosa; Anthropophobia; Anxiety disorder; Article; Autonomic dysfunction; Behavior disorder; Bipolar disorder; Body dysmorphic disorder; Bulimia; Cardiac anxiety; Claustrophobia; Cognitive defect; Controlled study; Conversion disorder; Cross‐dressing; Delirium; Delusional disorder; Dementia; Depersonalization; Depression; Derealization; Developmental disorder; Dhat syndrome; Dissociative disorder; Drug dependence; Dyspareunia; Emotional disorder; Erectile dysfunction; Exhibitionism; Faintness; Female; Frigidity; Frotteurism; Gender dysphoria; Human; Hypersomnia; Hypoactive sexual desire disorder; Hypochondriasis; ICD‐10; Illness anxiety disorder; Insomnia; Intermittent explosive disorder; Kleptomania; Libido disorder; Major clinical study; Male; Mental deficiency; Mixed anxiety and depression; Mood disorder; Multiple personality; Necrophilia; Neurasthenia; Neurosis; Nightmare; Obsessive compulsive disorder; Occupational disease; Panic; Pathological gambling; Personality disorder; Phobia; Postnatal depression; Posttraumatic stress disorder; Premature ejaculation; Prevalence; Priority journal; Psychasthenia; Psychogenic impotence; Psychogenic pain; Psychosis; Psychosomatic disorder; Public health; Puerperal psychosis; Randomized controlled trial; Sadomasochism; Schizoaffective psychosis; Schizophrenia; Sex with animals; Sexual arousal disorder; Sexual dysfunction; Sexual maturation; Sexual orientation; Sleep disorder; Sleep terror; Sleep walking; Somatization; Somatoform disorder; Tobacco dependence; Trichotillomania; Vaginism; Voyeurism -DOI: 10.2478/gp-2020-0008 -AB: There is evidence of a progressive increase in the number of Randomized Controlled Trials (RCTs) in the area of psychiatry. However, some areas of psychiatry receive more attention from researchers potentially to the detriment of others. Aiming to investigate main gaps for RCTs in psychiatry, the present bibliometric study analysed the bi‐annual and five‐year rates of RCTs in the main database of medical studies (Pubmed) over the 1999‐2018 period (n = 3,449). This analysis was carried out using the ICD‐10 mental and behavioural chapter. ICD‐10, was the edition of the manual used throughout the above period. Overall, after 16 years of considerable increase in the bi‐annual absolute number of RCTs, there has been a slowdown in the last 4 years, similar to other medical areas. Affective, organic and psychotic disorders, and depression, schizophrenia and dementia were the top studied groups and disorders respectively ‐ ahead of other groups/diagnoses. For substance use disorders, there has been a decrease of RCT in the last 5 years, in line with the fall of alcohol use disorder in the ranking of most studied disorders. Delirium and mild cognitive disorder are both ascending in this ranking. Personality disorders and mental retardation stand out as the least studied groups over the whole assessment period. Novel treatments, ease of access to patient populations, and 'clinical vogue', seem to be more important in guiding the undertaking of RCTs than the actual need as indicated by prevalence and/or burden of disorders and public health impact. Regarding specific disorders, acute/transient psychosis; mixed anxiety and depression; adjustment disorder; dissociative and conversion disorders; somatization; hypochondria; and neurasthenia, would deserve future RCTs. Clinical researchers and editors of scientific journals should give special attention to the less studied areas and disorders, when considering conducting and publishing RCT studies, respectively. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02326932/full - - -Record #54 of 151 -ID: CN-01779587 -AU: Bernardo DA -AU: Protzko S -AU: Harrington J -AU: Dudden RF -AU: Lee-Chiong T -TI: A bibliometric analysis of sleep research indexed in Pubmed, 2003-2007 -SO: Sleep medicine -YR: 2009 -VL: 10 -PG: S15 -XR: EMBASE 70238210 -PT: Journal article; Conference proceeding -KY: *Medline; *sleep; Data base; Government; Growth rate; Language; Medical Subject Headings; Meta analysis; Parasomnia; Randomized controlled trial; Scientific literature; Sleep apnea syndromes; Sleep disorder -AB: Introduction: Sleep Medicine has grown into a multi‐disciplinary field due to the rapid progression in knowledge, which resulted in an increase in scientific literature publications on this topic. Objective: To review the current status of publication activity on the subject of sleep and sleep disorders for the period 2003‐2007 in the top 20 journal publications of chosen specialties based on the journals' five‐year impact factor. Specifically, to determine which journals publish the most articles and the ratio of sleep articles in each publication, the types of references being published, and which subjects are most written about. Methods: The top 20 journal titles of chosen specialties were determined based on the five‐year impact factor from the Journal Citation Reports. A MEDLINE search for articles published from 2003 to 2007 was done using medical subject heading (MeSH) terms. EndNote and Excel were used to sort and compare the articles. FileMakerPro was used match the articles to the set of journals. Results: A total of 14244 references were found in the PubMed database, 4559 of which were published in 193 journals ranked on the top 20 journal publications of chosen specialties. There was an increase in publication activity over the past 5 years with an annual growth rate of 8%. The majority of the articles were in English and only 1009 (7.1%) were in other languages with English abstracts. The greatest contribution came from the USA (31%). Besides the core journals Sleep and Sleep Medicine Review, sleep articles comprise 1.5 to 25% of the total articles in the top 50 publications with the highest number of sleep articles. In the journals with five‐year impact factors of 10 or higher, sleep articles comprised only 0.3 to 2.7% of their publications. There has been an increase in the number of articles in foreign languages and multi‐center studies, 11.26% and 14% yearly, respectively. Metaanalysis articles also grew: 30% annually. Randomized controlled trials grew 7.81% per year. Of the studies that indicated the source of support, the majority was fromthe non‐government sector. Among the chosen major topics, sleep apnea, obstructive and sleep apnea syndromes were the most written about. REM sleep behavior disorder articles showed the greatest increase in the number of articles. Conclusion: In spite of the increasing number of articles on sleep, they still comprise a small proportion of the publications in major journals outside of the core clinical journals. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01779587/full - - -Record #55 of 151 -ID: CN-01301430 -AU: Ma Y -AU: Dong M -AU: Zhou K -AU: Mita C -AU: Liu J -AU: Wayne PM -TI: Publication trends in acupuncture research: a 20-year bibliometric analysis based on pubMed -SO: PloS one -YR: 2016 -VL: 11 -NO: 12 -CC: Complementary Medicine -PG: e0168123 -PM: PUBMED 27973611 -XR: EMBASE 613668958 -PT: Journal article -KY: *Acupuncture; *Bibliometrics; *Medline; *acupuncture; *publication; Acupuncture Therapy; Alternative medicine; Analgesia; Anesthesia; Animals; Arthritis; Article; Attention; Australia; Bibliometrics; Biomedical Research [trends]; Biomedicine; Brain ischemia; Brazil; Canada; Cerebrovascular accident; China; Controlled clinical trial; Controlled study; Diabetes mellitus; Dizziness; Dysmenorrhea; Dyspepsia; Edema; Fatigue; Female; Germany; Growth rate; Herpes zoster; Hot flush; Human; Humans; Hyperlipidemia; Internal medicine; Irritable colon; Italy; Japan; Journal Impact Factor; Journal impact factor; Labor pain; Medical literature; Medical research; Medline; Menopause; Meta analysis (topic); Mood disorder; Mood disorder/th [Therapy]; Multicenter study (topic); Nausea and vomiting; Neoplasm; Neuroscience; Nonhuman; Paralysis; Parasomnia; Pregnancy; Prevalence; PubMed; Publications [*trends]; Quantitative study; Randomized Controlled Trials as Topic; Randomized controlled trial; Randomized controlled trial (topic); Regression Analysis; Regression analysis; Sleep disorder; South Korea; Study design; Systematic review; Systematic review (topic); Temporomandibular joint disorder; Tinnitus; Trend study; United Kingdom; United States; Vertigo -DOI: 10.1371/journal.pone.0168123 -AB: Objective Acupuncture has become popular and widely practiced in many countries around the world. Despite the large amount of acupuncture‐related literature that has been published, broader trends in the prevalence and scope of acupuncture research remain underexplored. The current study quantitatively analyzes trends in acupuncture research publications in the past 20 years. Methods A bibliometric approach was used to search PubMed for all acupuncture‐related research articles including clinical and animal studies. Inclusion criteria were articles published between 1995 and 2014 with sufficient information for bibliometric analyses. Rates and patterns of acupuncture publication within the 20 year observational period were estimated, and compared with broader publication rates in biomedicine. Identified eligible publications were further analyzed with respect to study type/design, clinical condition addressed, country of origin, and journal impact factor. Results A total of 13,320 acupuncture‐related publications were identified using our search strategy and eligibility criteria. Regression analyses indicated an exponential growth in publications over the past two decades, with a mean annual growth rate of 10.7%. This compares to a mean annual growth rate of 4.5% in biomedicine. A striking trend was an observed increase in the proportion of randomized clinical trials (RCTs), from 7.4% in 1995 to 20.3% in 2014, exceeding the 4.5% proportional growth of RCTs in biomedicine. Over the 20 year period, pain was consistently the most common focus of acupuncture research (37.9% of publications). Other top rankings with respect to medical focus were arthritis, neoplasms/cancer, pregnancy or labor, mood disorders, stroke, nausea/vomiting, sleep, and paralysis/palsy. Acupuncture research was conducted in 60 countries, with the top 3 contributors being China (47.4%), United States (17.5%), and United Kingdom (8.2%). Retrieved articles were published mostly in complementary and alternative medicine (CAM) journals with impact factors ranging between 0.7 and 2.8 in the top 20 journals, followed by journals specializing in neuroscience, pain, anesthesia/analgesia, internal medicine and comprehensive fields. Conclusion Acupuncture research has grown markedly in the past two decades, with a 2‐fold higher growth rate than for biomedical research overall. Both the increases in the proportion of RCTs and the impact factor of journals support that the quality of published research has improved. While pain was a consistently dominant research focus, other topics gained more attention during this time period. These findings provide a context for analyzing strengths and gaps in the current state of acupuncture research, and for informing a comprehensive strategy for further advancing the field. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01301430/full - - -Record #56 of 151 -ID: CN-01771061 -AU: Bellon Saameno JA -AU: Martinez Canabate T -TI: Research into communication and health. A Spanish and international perspective through bibliometric analysis -SO: Atencion primaria / sociedad española de medicina de familia y comunitaria -YR: 2001 -VL: 27 -NO: 7 -PG: 452‐458 -PM: PUBMED 11334591 -XR: EMBASE 33474766 -PT: Journal article -KY: *bibliometrics; *doctor patient relation; *interpersonal communication; Article; Bibliometrics; Clinical Trials as Topic [statistics & numerical data]; Clinical trial; Communication; Controlled clinical trial; Human; Humans; Meta analysis; Meta‐Analysis as Topic; Patient Education as Topic; Patient education; Physician‐Patient Relations; Randomized Controlled Trials as Topic [statistics & numerical data]; Randomized controlled trial; Research; Spain; Statistics -DOI: 10.1016/s0212-6567(01)78835-x -AB: OBJECTIVES: 1. To find the scientific output on communication and health both in Spain and internationally. 2. To compare the two outputs according to the type of articles published and the design of the research. DESIGN: Descriptive and bibliometric study. MATERIAL: The data bases MEDLINE (1995‐2000) and IME (1990‐2000) and the books summarising papers from semFYC Congresses (1995‐2000) were used. MEASUREMENTS: The number of articles on MEDLINE published and indexed with the description <>, plus a series of subject describers that could be included under the heading <>, were counted. On the IME and in the semFYC congress summaries the describers <> were used. The articles indexed on MEDLINE‐IME were compared for their classification as original articles, clinical practice guidelines, review, editorial or letter to the editor. Original articles were classified in randomised and non‐randomised trials, meta‐analysis and observation studies. MAIN RESULTS: 6766 articles were found on MEDLINE, 42 on the IME (0.046% of the total indexed) and 34 summaries from semFYC congresses (1.47% of the total). Among the most commonly studied questions were found patients' information and education, professional stress and psychological interviews; among the least studied were difficult and aggressive patients, negotiation and people accompanying patients. The original articles on MEDLINE and IME were 70% and 37%; and review articles, 11% and 44%. 1.4% of MEDLINE articles were randomised trials; and 0.08%, meta‐analysis. CONCLUSIONS: Communication and health research is a young field that still requires descriptive studies. There is little scientific output in this area in Spain, with few original papers and too many reviews. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01771061/full - - -Record #57 of 151 -ID: CN-02466886 -AU: Liu Y -AU: Liu Q -AU: Jiang X -TI: Bibliometric analysis of hotspots and frontiers in cancer-related fatigue among ovarian cancer survivors -SO: PloS one -YR: 2022 -VL: 17 -NO: 9 -PG: e0274802 -PM: PUBMED 36137125 -XR: EMBASE 639084389 -PT: Journal article -KY: *bibliometrics; *cancer fatigue; *cancer survival; *cancer survivor; *drug tolerability; *ovary cancer; Activities of Daily Living; Adult; Adverse drug reaction; Article; Bibliometrics; Cancer Survivors; Cancer chemotherapy; Carcinoma, Ovarian Epithelial; Clinical trial; Controlled study; Cyclophosphamide; Double blind procedure; Drug efficacy; Drug safety; Drug therapy; Fatigue [etiology]; Female; Human; Humans; Ovarian Neoplasms [complications]; Overall survival; Quality of Life; Quality of life; Randomized Controlled Trials as Topic; Randomized controlled trial (topic); Side effect; Systematic review; United States; Web of Science -DOI: 10.1371/journal.pone.0274802 -AB: OBJECTIVES: To explore and analyze research hotspots and frontiers in CRF in ovarian cancer patients to provide an evidence‐based basis for scholars and policymakers. BACKGROUND: Ovarian cancer is one of the most common and lethal gynecological malignancies. Cancer‐related fatigue (CRF) is an annoying and pervasive side‐effect that seriously affects the activities of daily living and decreases the quality of life (QoL) of cancer survivors. METHODS: The literature was retrieved from the Web of Science Core Collection (WOSCC) from inception to 2021‐12‐31. CiteSpace was used to discuss research countries, institutions, authors, and keywords. RESULTS: This study ultimately included 755 valid publications, and the number of publications showed a gradual upward trend. The countries, institutions, authors, and journals that have published the most articles and cited the most frequently were the United States, the University of Texas MD Anderson Cancer Center, Michael Friedlander and Amit M Oza, Gynecologic Oncology, and Journal of Clinical Oncology. The top three high‐frequency keywords were Ovarian cancer, chemotherapy, and clinical trial. The top three keywords with the strongest citation bursts were cyclophosphamide, double‐blind, and open‐label. CONCLUSIONS: Conducting multi‐center, large‐sample, randomized controlled clinical trials to determine whether chemotherapeutic agents have severe adverse effects and to discuss the relationship between CRF and QoL and overall survival in cancer survivors are hotspots in this field. The new trends may be applying double‐blind, randomized controlled trials to clarify the causes of CRF and open‐label, randomized trials to determine the efficacy, safety, and tolerability of chemotherapeutic agents. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02466886/full - - -Record #58 of 151 -ID: CN-02794469 -AU: Chen J -AU: Wang Y -AU: Jiang R -AU: Qu Y -AU: Li Y -AU: Zhang Y -TI: Application of Mendelian randomized research method in oncology research: bibliometric analysis -SO: Frontiers in oncology -YR: 2024 -VL: 14 -PG: 1424812 -PM: PUBMED 39741977 -PT: Journal article -DOI: 10.3389/fonc.2024.1424812 -AB: BACKGROUND: Cancer has always been a difficult problem in the medical field, and with the gradual deepening of Genome‐wide association studies (GWAS), Mendelian randomization methods have been increasingly used to study cancer pathogenesis. In this study, we examine the literature on Mendelian cancer, summarize the status of the research, and analyze the development trends in the field. METHODS: Publications on "Mendelian Randomization ‐ Cancer" were retrieved and downloaded from the Web of Science Core Collection database. CiteSpace 6.2.R4, VOSviewer 1.6.19, Scimago Graphica 1.0.38, Bibliometrix R‐package, and a bibliometric online analysis platform were used for data analysis and visualization. An in‐depth analysis of country or region, authors, journals, keywords, and references was performed to provide insights into the content related to the field. RESULTS: A total of 836 articles were included in the analysis; 643 authors from 72 countries had published articles related to the field. China and Harvard University (among countries and institutions, respectively) had the highest number of articles. Martin, Richard M and Smith, George Davey were the largest contributors. A total of 27 cancers have been studied, with breast, colorectal, and liver cancers being the most studied. CONCLUSION: This study is the first to use bibliometric methods to visualize the application of Mendelian randomization analysis in the field of cancer, revealing research trends and research frontiers in the field. This information will provide a strong reference for cancer researchers and epidemiologic researchers. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02794469/full - - -Record #59 of 151 -ID: CN-02647332 -AU: Seta T -AU: Takahashi Y -AU: Yamashita Y -AU: Hiraoka M -AU: Nakayama T -TI: Outcome measures reported in abstracts of randomized controlled trials in leading clinical journals: a bibliometric study -SO: Journal of general and family medicine -YR: 2020 -VL: 21 -NO: 4 -PG: 119‐126 -PM: PUBMED 32742900 -PT: Journal article -DOI: 10.1002/jgf2.306 -AB: BACKGROUNDS: The CONSORT for Abstracts checklist published in 2008 recommends that authors report effect size for their studies. Meanwhile, the FDA strongly recommends reporting both ratio and difference measures. However, the measures of effect used in recent clinical trial reports remain unknown. This study is aimed to reveal trends regarding the measures of effect of interventions described in abstracts of recent randomized controlled trials (RCTs) in leading journals. METHODS: A bibliometric analysis of data was obtained by electronic searches. Human RCTs published in 2016 in the following five journals were searched using PubMed: Annals of Internal Medicine, British Medical Journal, Journal of American Medical Association, The Lancet, and New England Journal of Medicine. Main outcome is numbers of studies reporting each measure in their abstracts. RESULTS: Among abstracts of 334 articles, measures most frequently used were relative risk alone (n = 169), followed by absolute risk alone (n = 92), and raw data alone (n = 58). Reporting of the following measures was relatively limited: both ratio and difference measures (n = 8), raw data with ratio measures (n = 5), and raw data with difference measures (n = 2). None of the studies reported raw data with both ratio and difference measures. Only 15 articles described multiple measures of effect in their abstracts. CONCLUSIONS: More than half of the RCT abstracts published in the five leading journals in 2016 reported risk ratio alone to indicate effect size. Even abstracts in the five leading journals did not adhere fully to the CONSORT for Abstracts or FDA recommendations. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02647332/full - - -Record #60 of 151 -ID: CN-01744816 -AU: Wu GW -AU: Neuhauser D -TI: The literature on quality of life and organizational randomized clinical trials -SO: Medical care -YR: 1997 -VL: 35 -NO: 12 -PG: 1171‐1172 -PM: PUBMED 9413305 -XR: EMBASE 128204068 -PT: Journal article -KY: *bibliometrics; *health services research; *quality of life; *randomized controlled trial; Bibliometrics; CD‐ROM; Clinical trial; Compact disk; Controlled clinical trial; Editorial; Health Services Research; Human; Humans; Quality of Life; Randomized Controlled Trials as Topic -DOI: 10.1097/00005650-199712000-00001 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01744816/full - - -Record #61 of 151 -ID: CN-01995256 -AU: Kumar S -AU: Mohammad H -AU: Vora H -AU: Kar K -TI: Reporting Quality of Randomized Controlled Trials of Periodontal Diseases in Journal Abstracts-A Cross-sectional Survey and Bibliometric Analysis -SO: Journal of evidence-based dental practice -YR: 2018 -VL: 18 -NO: 2 -PG: 130‐141.e22 -PM: PUBMED 29747793 -XR: EMBASE 629431343 -PT: Journal article -KY: *bibliometrics; *periodontal disease; Bibliometrics; Brazil; Controlled study; Cross‐Sectional Studies; Cross‐sectional study; Europe; Human; Humans; India; Periodontal Diseases; Questionnaire; Randomized Controlled Trials as Topic; Randomized controlled trial; Randomized controlled trial (topic); Surveys and Questionnaires -DOI: 10.1016/j.jebdp.2017.08.005 -AB: OBJECTIVE: Randomized controlled trials (RCTs) by proper design, conduct, analysis, and reporting provide reliable information in clinical care. Reporting of RCT abstracts is of equal importance as there is evidence that many clinicians will change their clinical decisions based on RCT abstracts. The reporting quality of RCT abstracts has been suboptimal. It is not clear whether the reporting quality is related to the journal metrics. The main objective of this study is to conduct a cross‐sectional survey to evaluate the reporting quality of RCTs of periodontal diseases in journal abstracts and to perform a bibliometric analysis. The null hypothesis was that there is no association between the journal metrics (5‐year impact factor, Eigenfactor score, and Article Influence Score), abstract metrics (word count, and number of authors), journal endorsement of Consolidated Standards of Reporting Trials (CONSORT), and the overall quality of reporting of CONSORT RCT abstract‐modified checklist questions. MATERIALS: CONSORT RCT abstract extension checklist with explanation and elaboration was used and modified to assess the quality of reporting of RCT abstracts of periodontal diseases in the journal abstracts in the year 2012. Bibliometric analysis of journal metrics (5‐year impact factor, Eigenfactor score, and Article Influence Score) and abstract metrics (number of authors and abstract word count), the geographic distribution, and the CONSORT‐endorsing journal abstracts was compared with the reporting quality of RCT abstracts in periodontal diseases. Calibration and intrarater agreement were done before the data collection and analysis. A second reviewer was consulted for independent evaluation and clarification as needed. For descriptive analysis, the values of continuous variables were expressed as median and interquartile ranges (IQRs) and as proportion percent for binary categorical variables. For association analysis between the binary (yes/no) response variable and the continuous variable, the Mann‐Whitney test (for independent samples) was used. For examining the association between 2 categorical variables, Fisher's exact test was used. The chi‐square test was performed to examine the association between 2 sets of binary response variables (yes/no). A P value of < .05 was considered statistically significant. All analyses were conducted using SAS, version 9.4. CONCLUSION: The reporting quality of RCT of periodontal diseases in the journal abstracts published in 2012 needs substantial improvement. These items have been laid out in this study to help all stakeholders‐authors, clinicians, researchers, peer reviewers, journal editors, and publishers to take note and help with the improvement of the same. Despite few significant associations in the bibliometric factors analyzed with better reporting, the results overall led to the failure to reject the null hypothesis that there is no association between the journal metrics, word count, and number of authors and the quality of reporting of CONSORT RCT abstract‐modified checklist questions. RESULTS: A total of 198 RCT abstracts of periodontal diseases in the year 2012 from 57 journals were included in the study. Fifteen journals, listed as endorsers of CONSORT, contributed 108 RCT abstracts. Four journals (Journal of Periodontology, Journal of Clinical Periodontology, Clinical Oral Implants Research, and European Journal of Oral Implantology) contributed 84 of 198 RCT abstracts in 2012. European countries contributed the majority (n = 81, 40.91%) of RCT abstracts. Among 31 countries in this study, United States contributed the most RCTs (n = 28, 14.14%) followed by India (24, 12.12%), Italy (n = 22, 11.11%), and Brazil (n = 20, 10.1%). The frequency of journal metrics were 5‐year impact factor (median 2.316; IQR: 1.439‐2.970); Eigenfactor score (0.00474; 0.00202‐0.01395); and Article Influence Score (0.553; 0.382‐0.755). The number of authors in 198 RCT abstracts ranged between 2 and 20 (median n = 5, IQR: 4‐6), whereas the word count ranged between 48 and 569 (median 235, IQR: 205‐269). All RCT abstracts reported the experimental interventions (checklist question #5, frequency 100%). Some items were almost always reported‐participant eligibility criteria (#3, 99%); comparison interventions (#6, 99.5%); specific objective or hypothesis (#7, 99.5%); primary outcome (#8, 99.5%); and reporting trial results as a summary (#16, 98.5%). All RCT abstracts never reported how the allocations were concealed (#11, 0) and the source of funding for the trials (#23, 0). Some items were almost always never reported‐the number of participants included in the analysis for each intervention (#15, 2%); trial registration number (#21, 2.5%); name of trial register (#22, 2.5%); and how the randomization or sequence generation was done (#22). Dismal reporting was noted in many checklist questions including the identification of the study as randomized in the title #1, 51%; design of the trial #2, 32.8%; trial setting #4, 3.5%; randomization #10, 3.5%; blinding #12, 21.7%; details about blinding #13, 8.1%; number of participants randomized to each intervention #14, 26.3%; effect size #17, 13.6%; precision of the estimate of the effect #18, 6.1%; and adverse effects #19, 14.1%. Strikingly, there was a very high reporting of statistical significance #25, 92.4%. European countries, in particular, reported relatively better than other countries in essential questions such as #17 effect size reporting, and #18 precision (uncertainty), which have been largely unreported by rest of the countries. Finally, despite the majority of RCTs published in 2012 were by CONSORT‐endorsing journals, there was no difference in the quality of reporting in majority of checklist items when compared with journals not listed as CONSORT endorsers. With few exceptions, there was no statistically significant association between the majority of the CONSORT RCT abstract checklist questions and the journal metrics and abstract metrics analyzed in this study. Unexpectedly, lower ranking journals in journal metrics reported certain essential checklist questions relatively better. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01995256/full - - -Record #62 of 151 -ID: CN-01978256 -AU: Luc JGY -AU: Archer MA -AU: Arora RC -AU: Bender EM -AU: Blitz A -AU: Cooke DT -AU: Hlci TN -AU: Kidane B -AU: Ouzounian M -AU: Varghese TK -AU: et al. -TI: Social Media Improves Cardiothoracic Surgery Literature Dissemination: results of a Randomized Trial -SO: Annals of thoracic surgery -YR: 2020 -VL: 109 -NO: 2 -PG: 589‐595 -PM: PUBMED 31404547 -XR: EMBASE 629071958 -PT: Journal article -KY: *heart surgery; *social media; Adult; Article; Bibliometrics; Controlled study; Education; Female; Human; Human experiment; Information Dissemination; Male; Prospective study; Publishing [*statistics & numerical data]; Randomized controlled trial; Social Media; Thoracic Surgery -DOI: 10.1016/j.athoracsur.2019.06.062 -AB: BACKGROUND: The Thoracic Surgery Social Media Network (TSSMN) represents a collaborative effort of leading journals in cardiothoracic surgery to highlight publications via social media, specifically Twitter. We conducted a prospective randomized trial to determine the effect of scheduled tweeting on nontraditional bibliometrics of dissemination. METHODS: A total of 112 representative original articles (2017‐2018) were selected and randomized 1:1 to an intervention group to be tweeted via TSSMN or a control (non‐tweeted) group. Four articles per day were tweeted by TSSMN delegates for 14 days. Primary endpoints included change in article‐level metrics (Altmetric) score pre‐tweet and post‐tweet compared with the control group. Secondary endpoints included change in Twitter analytics day 1 post‐tweet and day 7 post‐tweet for each article compared with baseline. RESULTS: Tweeting via TSSMN significantly improved article Altmetric scores (pre‐tweet 1 vs post‐tweet 8; P < .001), Mendeley reads (pre‐tweet 1 vs post‐tweet 3; P < .001), and Twitter impressions (day 1 post‐tweet 1599 vs day 7 post‐tweet 2296; P < .001). Subgroup analysis demonstrates that incorporating photos into the tweets trended toward increased link clicks to the full‐text article (P = .08) whereas tweeting at 1 pm Eastern Standard Time and 9 pm Eastern Standard Time generated the highest and lowest audience reach (P = .022), respectively. Articles published in adult cardiac surgery achieved the highest change in Altmetric score (P = .028) and Mendeley reads (P = .028), and were more likely to be retweeted (P = .042) than were those published on education, general thoracic surgery, and congenital surgery. CONCLUSIONS: Social media highlights of scholarly literature via TSSMN Twitter activity improves article Altmetric scores, Mendeley reads, and Twitter analytics, with dissemination to a greater audience. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01978256/full - - -Record #63 of 151 -ID: CN-02131965 -AU: Luc JGY -AU: Archer MA -AU: Arora RC -AU: Bender EM -AU: Blitz A -AU: Cooke DT -AU: Hlci TN -AU: Kidane B -AU: Ouzounian M -AU: Varghese TK -AU: et al. -TI: Does Tweeting Improve Citations? One-Year Results From the TSSMN Prospective Randomized Trial -SO: Annals of thoracic surgery -YR: 2021 -VL: 111 -NO: 1 -PG: 296‐300 -PM: PUBMED 32504611 -XR: EMBASE 632004182 -PT: Journal article -KY: *prospective study; Article; Bibliometrics; Controlled study; Follow up; Human; Periodicals as Topic; Prospective Studies; Publishing [*statistics & numerical data]; Quantitative analysis; Randomization; Randomized controlled trial; Social Media; Social media; Thoracic Surgery; Thorax surgery; Time Factors -DOI: 10.1016/j.athoracsur.2020.04.065 -AB: BACKGROUND: The Thoracic Surgery Social Media Network (TSSMN) is a collaborative effort of leading journals in cardiothoracic surgery to highlight publications via social media. This study aims to evaluate the 1‐year results of a prospective randomized social media trial to determine the effect of tweeting on subsequent citations and nontraditional bibliometrics. METHODS: A total of 112 representative original articles were randomized 1:1 to be tweeted via TSSMN or a control (non‐tweeted) group. Measured endpoints included citations at 1 year compared with baseline, as well as article‐level metrics (Altmetric score) and Twitter analytics. Independent predictors of citations were identified through univariable and multivariable regression analyses. RESULTS: When compared with control articles, tweeted articles achieved significantly greater increase in Altmetric scores (Tweeted 9.4 ± 5.8 vs Non‐tweeted 1.0 ± 1.8, P < .001), Altmetric score percentiles relative to articles of similar age from each respective journal (Tweeted 76.0 ± 9.1 percentile vs Non‐tweeted 13.8 ± 22.7 percentile, P < .001), with greater change in citations at 1 year (Tweeted +3.1 ± 2.4 vs Non‐Tweeted +0.7 ± 1.3, P < .001). Multivariable analysis showed that independent predictors of citations were randomization to tweeting (odds ratio [OR] 9.50; 95% confidence interval [CI] 3.30‐27.35, P < .001), Altmetric score (OR 1.32; 95% CI 1.15‐1.50, P < .001), open‐access status (OR 1.56; 95% CI 1.21‐1.78, P < .001), and exposure to a larger number of Twitter followers as quantified by impressions (OR 1.30, 95% CI 1.10‐1.49, P < .001). CONCLUSIONS: One‐year follow‐up of this TSSMN prospective randomized trial importantly demonstrates that tweeting results in significantly more article citations over time, highlighting the durable scholarly impact of social media activity. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02131965/full - - -Record #64 of 151 -ID: CN-01757008 -AU: Manriquez M J -AU: Valdivia C G -AU: Rada G G -AU: Letelier S LM -TI: Critical assessment of randomized controlled trials published in biomedical Chilean journals -SO: Revista medica de Chile -YR: 2005 -VL: 133 -NO: 4 -PG: 439‐446 -PM: PUBMED 15953951 -XR: EMBASE 43126738 -PT: Journal article -KY: *methodology; *publication; *randomized controlled trial; Article; Bibliometrics; Chile; Clinical trial; Controlled clinical trial; Evaluation study; Human; Humans; Periodicals as Topic; Randomized Controlled Trials as Topic [*standards, statistics & numerical data]; Research Design [*standards]; Standard; Statistics -DOI: 10.4067/s0034-98872005000400007 -AB: Background: Well designed clinical trials yield the strongest evidence for the effect of health care interventions. Aim: To assess the methodological quality of the design and report of randomized clinical trials in a sample, published in biomedical Chilean journals between 1980 and 2002. Material and methods: All trials identified by hand search by the Unit of Evaluation of Technologies in Health, were assessed for quality of randomization, blinding, analysis of results and other characteristics of trial design, along with the application of Jadad's Score, that assesses the methodological quality of clinical trials in a scale that ranges from 0 to 5. Results: Twenty eight trials were found and assessed, 75% (n=21) specified the method used for randomization, 29% (n=8) described a correct allocation concealment and 39% (n=11) were double blinded. Withdrawals and dropouts were correctly reported in 21% (n=6) of the articles, whereas intention to treat analysis was done only in one. Thirteen trials had a Jadad score equal or higher than 3 points. Conclusions: Several design deficiencies were found in the trials assessed. It is difficult to know if methodological weaknesses are due to incomplete reports or to methodologically poor designs. Adopting initiatives like the CONSORT can help improve the quality of randomized clinical trials published in Biomedical Chilean journals. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01757008/full - - -Record #65 of 151 -ID: CN-01739146 -AU: Bereczki D -AU: Gesztelyi G -TI: A Hungarian example for handsearching specialized national healthcare journals of small countries for controlled trials. Is it worth the trouble? -SO: Health libraries review -YR: 2000 -VL: 17 -NO: 3 -PG: 144‐147 -PM: PUBMED 11186806 -XR: EMBASE 31388539 -PT: Journal article -KY: *information retrieval; *publication; *randomized controlled trial; Article; Bibliometrics; Clinical trial; Controlled clinical trial; Human; Humans; Hungary; Information Storage and Retrieval [*methods]; Methodology; Neuroscience; Neurosciences; Periodicals as Topic; Randomized Controlled Trials as Topic -DOI: 10.1046/j.1365-2532.2000.00280.x -AB: The objective of this study was to determine whether a Hungarian language journal of clinical neuroscience, which is not indexed in MEDLINE, contains any reports of randomized or quasi‐randomized clinical trials that are not also reported in MEDLINE‐indexed publications. A cover‐to‐cover handsearch was performed of the journal Clinical Neuroscience/Ideggyógyászati Szemle, the official journal of Hungarian societies of neurology, neurosurgery, psychiatry and related clinical neurosciences, from its first volume in 1950 to the end of 1998; and a search of MEDLINE for other reports of the trials identified. Clinical trials in which patients were allocated to interventions by randomized, quasi‐randomized or possibly randomized means were identified. Controlled trials were tabulated and coded as randomized controlled trials or controlled clinical trials according to the definitions of the Handsearch Manual of the Cochrane Collaboration. We identified three randomized and eight quasi‐randomized trials. Six of the 11 trials were not reported in MEDLINE indexed publications. In conclusion, to obtain a comprehensive controlled trials register, specialized healthcare journals printed in small numbers in the national languages of small countries should be searched. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01739146/full - - -Record #66 of 151 -ID: CN-01718718 -AU: Watson R -TI: Intervention studies in JCN -SO: Journal of clinical nursing -YR: 2007 -VL: 16 -NO: 9 -PG: 1591‐1592 -PM: PUBMED 17727578 -XR: EMBASE 350310871 -PT: Journal article -KY: *bibliometrics; *methodology; *nursing research; *publication; Bibliometrics; Classification; Editorial; Human; Humans; Intervention study; Nursing Research [classification, *organization & administration]; Organization and management; Periodicals as Topic [*statistics & numerical data]; Placebo Effect; Placebo effect; Randomized Controlled Trials as Topic; Randomized controlled trial; Research Design [*statistics & numerical data]; Statistics -DOI: 10.1111/j.1365-2702.2007.01938.x -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01718718/full - - -Record #67 of 151 -ID: CN-02247389 -AU: Parikh A -AU: Markle J -AU: Venincasa M -AU: Kuriyan AE -AU: Gupta M -AU: Sridhar J -TI: POSITIVE RESULTS BIAS AND IMPACT FACTOR IN RETINA CLINICAL TRIALS 2016 to 2019 -SO: Retina (Philadelphia, Pa.) -YR: 2021 -VL: 41 -NO: 8 -PG: 1697‐1700 -PM: PUBMED 33438897 -XR: EMBASE 634000721 -PT: Journal article -KY: *journal impact factor; *randomized controlled trial (topic); *retina; Bias; Bibliometrics; Human; Humans; Journal Impact Factor; Publication Bias; Publishing; Randomized Controlled Trials as Topic; Retina; Retina disease /therapy; Retinal Diseases [*therapy]; Retrospective Studies; Retrospective study; Statistical bias -DOI: 10.1097/IAE.0000000000003107 -AB: PURPOSE: To assess for a positive results bias in recently published randomized controlled trials in the field of vitreoretinal disease. METHODS: A bibliometric analysis was conducted examining randomized controlled trials published in the field of retina between January 1, 2016, and December 31, 2019. Studies were classified as positive result or negative result based on the statistical significance of their primary outcome. Publication date and sample size were documented. These variables were compared against Journal Citation Reports Impact Factor in the year of publication. RESULTS: Two hundred and eighty‐eight randomized controlled trials from 64 unique journals were included and analyzed. One hundred and eighty‐five (64.2%) studies were classified as positive result, and 103 (35.8%) studies were classified as negative result. There was no association between impact factor and positive result. Studies classified as positive result had larger sample sizes, and higher sample size was associated with higher impact factor. CONCLUSION: These results do not support the presence of a recent positive results bias in retina randomized controlled trials. This is reassuring, although several factors could be contributing to this finding including studies that were conducted but never submitted and selective reporting of outcomes. Thus, it will be important to remain cognizant of potential publication biases moving forward. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02247389/full - - -Record #68 of 151 -ID: CN-02247127 -AU: Mitra AN -AU: Ananth CV -AU: Brandt JS -TI: 833 A bibliometric analysis of obstetrics and gynecology articles with the highest relative citation ratios, 1980-2019 -SO: American journal of obstetrics and gynecology -YR: 2021 -VL: 224 -NO: 2 -PG: S518‐S519 -XR: EMBASE 2010868098 -PT: Journal article; Conference proceeding -KY: *gynecology; *obstetrics; Conference abstract; Consensus; Controlled study; Human; Observational study; Randomized controlled trial; Risk assessment; Risk factor -DOI: 10.1016/j.ajog.2020.12.856 -AB: Objective: The relative citation ratio (RCR) is a novel bibliometric tool that quantifies the impact of research articles. The RCR is calculated by the number of citations that an article receives per year divided by an expected citation rate that is derived from performance of articles in the same field and benchmarked to a peer comparison group. The purpose of this study was to evaluate the OBGYN articles with the highest RCR and compare characteristics of these articles with articles that are top‐cited. Study Design: We performed a cross sectional bibliometric study looking at the OBGYN articles with the highest RCR in the NIH Open Citations Collection (1980‐2019). The 100 articles with the highest RCR and the 100 top‐cited articles were selected for further review. Each article was evaluated using metrics of influence and translation as well as other characteristics. We compared the top‐100 articles with highest RCR versus top‐cited articles after excluding articles featured on both lists. We calculated relative risks (95% confidence intervals). Results: A total of 323,673 OBGYN articles were identified. There were 60 articles in common between the highest RCR and top‐cited groups. The majority of articles with the highest RCR were observational studies, reviews, and consensus statements, and a minority were randomized controlled trials (RCTs). Articles with highest RCR received fewer absolute citations, but had higher numbers of citations per year. Articles with the highest RCR were more likely to address obstetrics topics, to be RCTs, and to be published open access. Comparison of article characteristics are described in the TABLE. Conclusion: Nearly half of the 100 articles with highest RCR would not have been recognized as citation classics by conventional bibliometric analysis. The RCR is a novel bibliometric tool that does not rely on absolute citation rates and provides important insights into research in OBGYN. [Formula presented] -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02247127/full - - -Record #69 of 151 -ID: CN-02818711 -AU: Govindasamy K -AU: Elayaraja M -AU: Abderrahman AB -AU: Parpa K -AU: Katanic B -AU: Granacher U -TI: The Effect of Leisure-Time Exercise on Mental Health Among Adults: a Bibliometric Analysis of Randomized Controlled Trials -SO: Healthcare (Basel, Switzerland) -YR: 2025 -VL: 13 -NO: 5 -PM: PUBMED 40077139 -PT: Journal article -DOI: 10.3390/healthcare13050575 -AB: Background: Adequate levels of leisure‐time exercise (LTE) are associated with mental health benefits. Despite increased research in recent years through randomized controlled trials (RCTs), a systematic literature review summarizing these findings is lacking. Here, we examined publication trends, impact, and research gaps regarding LTE's effects on mental health in the form of a bibliometric analysis. Methods: Five electronic databases (PubMed, EMBASE, Web of Science, Ovid Medline, and the Cumulative Index for Nursing and Allied Health Literature) were searched from their inception until 20 November 2024. Citations were independently screened by two authors and included based on pre‐determined eligibility criteria. Bibliometric analysis was conducted using SciVal and VOSviewer under five themes: (1) descriptive analysis, (2) network analysis, (3) thematic mapping, (4) co‐citation and co‐occurrence analysis, and (5) bibliometric coupling. Results: The systematic search identified 5792 citations, of which 78 RCTs met the inclusion criteria. Only one study was conducted in a low‐ or middle‐income country. Sixty‐four percent of studies were published in quartile‐one journals. Most studies were conducted in the United States, followed by Australia, Canada, and the United Kingdom. National collaborations yielded the highest citation rates, reflecting the influence of cultural and social norms on exercise and mental health. Research gaps were identified with regards to the validity of mental health measures, the paucity of data from low‐ and middle‐income countries, and emerging research sources. Conclusions: This bibliometric analysis highlights the existing evidence on LTE's impact on mental health and identifies areas for future research and policy. Trials exploring valid mental health outcomes, biomarkers such as mood and oxidative stress, and collaborative research are needed, particularly in underrepresented regions of the world. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02818711/full - - -Record #70 of 151 -ID: CN-01666644 -AU: McCullough JPA -AU: Lipman J -AU: Presneill JJ -TI: The Statistical Curriculum Within Randomized Controlled Trials in Critical Illness -SO: Critical care medicine -YR: 2018 -VL: 46 -NO: 12 -PG: 1985‐1990 -PM: PUBMED 30119072 -XR: EMBASE 625025454 -PT: Journal article -KY: *critical illness; *curriculum; Article; Bibliometrics; Chi square test; Clinical practice; Clinician; Contingency table; Controlled study; Critical Care; Curriculum; Data Interpretation, Statistical; Data extraction; Human; Humans; Intensive care; Nonparametric test; Outcome assessment; Publishing; Randomized Controlled Trials as Topic [*methods]; Randomized controlled trial -DOI: 10.1097/CCM.0000000000003380 -AB: OBJECTIVES: Incomplete biostatistical knowledge among clinicians is widely described. This study aimed to categorize and summarize the statistical methodology within recent critical care randomized controlled trials. DESIGN: Descriptive analysis, with comparison of findings to previous work. SETTING: Ten high‐impact clinical journals publishing trials in critical illness. SUBJECTS: Randomized controlled trials published between 2011 and 2015 inclusive. INTERVENTIONS: Data extraction from published reports. MEASUREMENTS AND MAIN RESULTS: The frequency and overall proportion of each statistical method encountered, grouped according to those used to generate each trial's primary outcome and separately according to underlying statistical methodology. Subsequent analysis compared these proportions with previously published reports. A total of 580 statistical tests or methods were identified within 116 original randomized controlled trials published between 2011 and 2015. Overall, the chi‐square test was the most commonly encountered (70/116; 60%), followed by the Cox proportional hazards model (63/116; 54%) and logistic regression (53/116; 46%). When classified according to underlying statistical assumptions, the most common types of analyses were tests of 2 × 2 contingency tables and nonparametric tests of rank order. A greater proportion of more complex methodology was observed compared with trial reports from previous work. CONCLUSIONS: Physicians assessing recent randomized controlled trials in critical illness encounter results derived from a substantial and potentially expanding range of biostatistical methods. In‐depth training in the assumptions and limitations of these current and emerging biostatistical methods may not be practically achievable for most clinicians, making accessible specialist biostatistical support an asset to evidence‐based clinical practice. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01666644/full - - -Record #71 of 151 -ID: CN-01725484 -AU: Patsopoulos NA -AU: Analatos AA -AU: Ioannidis JP -TI: Relative citation impact of various study designs in the health sciences -SO: JAMA -YR: 2005 -VL: 293 -NO: 19 -PG: 2362‐2366 -PM: PUBMED 15900006 -XR: EMBASE 40676758 -PT: Journal article -KY: *health science; Article; Bibliometrics; Biomedical Research; Case control study; Case report; Clinical trial; Cohort analysis; Controlled clinical trial; Cost effectiveness analysis; Decision making; Meta analysis; Priority journal; Publishing [*statistics & numerical data]; Randomized controlled trial; Research Design [*statistics & numerical data]; Systematic review -DOI: 10.1001/jama.293.19.2362 -AB: Context: The relative merits of various study designs and their placement in hierarchies of evidence are often discussed. However, there is limited knowledge about the relative citation impact of articles using various study designs. Objective: To determine whether the type of study design affects the rate of citation in subsequent articles. Design and Setting: We measured the citation impact of articles using various study designs ‐ including meta‐analyses, randomized controlled trials, cohort studies, case‐control studies, case reports, nonsystematic reviews, and decision analysis or cost‐effectiveness analysis ‐ published in 1991 and in 2001 for a sample of 2646 articles. Main Outcome Measure: The citation count through the end of the second year after the year of publication and the total received citations. Results: Meta‐analyses received more citations than any other study design both in 1991 (P<.05 for all comparisons) and in 2001 (P<.001 for all comparisons) and both in the first 2 years and in the longer term. More than 10 citations in the first 2 years were received by 32.4% of meta‐analyses published in 1991 and 43.6% of meta‐analyses published in 2001. Randomized controlled trials did not differ significantly from epidemiological studies and nonsystematic review articles in 1991 but clearly became the second‐cited study design in 2001. Epidemiological studies, nonsystematic review articles, and decision and cost‐effectiveness analyses had relatively similar impact; case reports received negligible citations. Meta‐analyses were cited significantly more often than all other designs after adjusting for year of publication, high journal impact factor, and country of origin. When limited to studies addressing treatment effects, meta‐analyses received more citations than randomized trials. Conclusion: Overall, the citation impact of various study designs is commensurate with most proposed hierarchies of evidence. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01725484/full - - -Record #72 of 151 -ID: CN-02588333 -AU: Rooney MK -AU: Sharifi B -AU: Ludmir EB -AU: Fuller CD -AU: Warner JL -TI: Factors Associated With Altmetric Attention Scores for Randomized Phase III Cancer Clinical Trials -SO: JCO clinical cancer informatics -YR: 2023 -VL: 7 -PG: e2300082 -PM: PUBMED 37552823 -PT: Journal article -KY: Bibliometrics; Humans; Journal Impact Factor; Neoplasms [diagnosis, therapy]; Social Media; United States -DOI: 10.1200/CCI.23.00082 -AB: PURPOSE: Altmetric Attention Scores (Altmetrics) are real‐time measures of scientific impact and attention through various public outlets, including news, blogs, and social media. Herein, we aimed to describe and characterize the relationship between Altmetrics, conventional impact metrics, and features of published cancer clinical trials. METHODS: We identified two‐arm phase III cancer randomized clinical trials with a superiority end point and publication date between 2015 and 2020 from HemOnc and tabulated the following data: Altmetric, study positivity, US Food and Drug Administration (FDA) registration trial status, cancer site/category, treatment context (curative or palliative), trial design, primary end point type, experimental/control arm modality, and journal tier. We further collected conventional bibliometrics including the number of citations and relative citation ratio (RCR) for all published studies. Multiple linear regression modeling identified clinical trial factors predictive of Altmetrics, with alpha = .05 defining statistical significance. RESULTS: Altmetrics were found for 681 (98%) of 698 publications, with a median score of 38.5 (IQR, 13‐132.8). FDA registration studies (β [95% CI], 84.7 [48.8 to 120.6]; P < .001), studies reporting on curative (as opposed to palliative) interventions (‐29 [‐53.7 to ‐4.4]; P = .02), genitourinary trials (73.2 [28.1 to 118.2]; P = .001), studies published in tier 1 journals (P < .001), and those with an increased number of citations per year (0.81 [0.66 to 0.95]; P < .001) were significantly associated with increased engagement as measured by Altmetrics. Furthermore, there was a strong correlation between all collected bibliometrics and Altmetrics (R2 = 0.63, 0.68, and 0.67; P < .001 for citation count, citations per year, and RCR, respectively). CONCLUSION: FDA registration trials describing curative interventions, studies published in traditionally defined high‐impact journals, and genitourinary trial publications tend to have the greatest Altmetrics. We observed a strong relationship between Altmetrics and conventional bibliometrics. The significance and consequences of these relationships warrant further investigation. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02588333/full - - -Record #73 of 151 -ID: CN-02143665 -AU: Steele L -AU: Livesey A -AU: Hong A -AU: Thomson J -AU: Flohr C -TI: Comparison of registered and published outcomes in randomized trials in dermatology journals: a cross-sectional analysis -SO: British journal of dermatology -YR: 2020 -VL: 183 -NO: 6 -PG: 1134‐1136 -PM: PUBMED 32652527 -XR: EMBASE 632328296 -PT: Journal article -KY: *Dermatology; *Periodicals as Topic; *cross‐sectional study; *dermatology; *outcome assessment; Bibliometrics; Controlled study; Cross‐Sectional Studies; Dredging; Editor; Human; Humans; Letter; Medical literature; Outcome reporting bias; Randomized Controlled Trials as Topic; Randomized controlled trial -DOI: 10.1111/bjd.19397 -AB: A potential source of bias in randomised controlled trial (RCTs) is selective outcome reporting bias, where outcomes for reporting are chosen based on the significance of their results.1 Significance can arise by chance when multiple tests are performed ("data dredging"). To avoid this problem, a main outcome (a "primary outcome") should be pre‐specified prior to data collection in a time‐stamped, publicly‐available trial registry. Prospective registration has been a prerequisite for publication amongst International Committee of Medical Journal Editors (ICMJE) member journals since 2005. However, even when trials are prospectively registered, selective outcome bias reporting can occur if the primary outcome reported in the manuscript does not match the pre‐specified primary outcome in the trial registry.2. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02143665/full - - -Record #74 of 151 -ID: CN-02143555 -AU: Slim K -AU: Mattevi C -AU: Badon F -AU: Lecomte C -AU: Selvy M -TI: The wave of "opinion articles" in the coverage of COVID-19 in surgical literature -SO: Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie -YR: 2020 -VL: 405 -NO: 6 -PG: 877‐878 -PM: PUBMED 32676739 -XR: EMBASE 2005594449 -PT: Journal article -KY: *Betacoronavirus; *Bibliometrics; *Coronavirus Infections; *Data Accuracy; *Pandemics; *Pneumonia, Viral; *coronavirus disease 2019; Article; Attitude; COVID‐19; Controlled study; Editor; Human; Humans; Randomized controlled trial; SARS‐CoV‐2; Surgery -DOI: 10.1007/s00423-020-01932-w -AB: Introduction: The COVID‐19 pandemic is having a deep impact on our surgical practice and scientific publishing output. Methods: The 100 best‐ranked “surgery journals” were selected. The contents of the March, April, May, and June 2020 issues and ahead‐of‐print articles were screened. The retrieved articles on COVID‐19 were separated into two categories: “opinion articles” and “scientific articles,” i.e., randomized trials and original articles with structured methods and results. The number of COVID articles published in the TOP‐10 journals was compared with that of COVID articles published elsewhere. Results: There were 59 COVID original articles (8%). The great majority of articles were opinion articles (83.4%). Almost 40% of COVID articles were published in the TOP‐10 journals. Conclusion: Original COVID articles (the core of our knowledge) are scant. Faced with a novel disease, neither the authors nor the editors should be criticized regarding this situation. The future step should be to publish high‐quality papers in the setting of a major health crisis. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02143555/full - - -Record #75 of 151 -ID: CN-01727956 -AU: Rychetnik L -AU: Nutbeam D -AU: Hawe P -TI: Lessons from a review of publications in three health promotion journals from 1989 to 1994 -SO: Health education research -YR: 1997 -VL: 12 -NO: 4 -PG: 491‐504 -PM: PUBMED 10176374 -XR: EMBASE 28006028 -PT: Journal article -KY: *health promotion; *scientific literature; Article; Bibliometrics; Classification; Clinical trial; Controlled clinical trial; Health Promotion; Health Services Research; Health care quality; Health education; Humans; Information; Periodicals as Topic; Priority journal; Publishing; Randomized controlled trial; Research; Research Design -DOI: 10.1093/her/12.4.491 -AB: A thematic analysis was undertaken of 72 editorials in three leading health promotion journals, Health Education Research: Theory & Practice, Health Education Quarterly and Health Promotion International, from 1989 to 1994. The three main themes which emerged were (1) the need to broaden health promotion interventions, (2) the need to promote rigour and professionalism in the discipline of health promotion, and (3) the need to respond to the information requirements of practitioners. Against this context, we conducted a content analysis of the journals, examining the nature of the 649 peer‐reviewed publications in the same time period. Categories from the traditional bio‐medical 'stages of research' models had to be adapted before full classification of articles published was feasible. The largest number of articles published could be termed descriptive research, followed by studies developing and validating health promotion measurement tools and health promotion theory. The proportion of program evaluations was small and the proportion of randomized controlled trials ('highest quality evidence' of effectiveness) decreased over time. Dissemination studies were also poorly represented in spite of this being identified in editorials as an important professional need. Ways to redress some of the imbalances observed are discussed. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01727956/full - - -Record #76 of 151 -ID: CN-01776192 -AU: Almerie MQ -AU: Matar HE -AU: Jones V -AU: Kumar A -AU: Wright J -AU: Wlostowska E -AU: Adams CE -TI: Searching the polish medical bibliography (polska bibliografia lekarska) for trials -SO: Health information and libraries journal -YR: 2007 -VL: 24 -NO: 4 -PG: 283‐286 -PM: PUBMED 18005303 -XR: EMBASE 350115804 -PT: Journal article -KY: *bibliographic database; *information retrieval; *medical informatics; *randomized controlled trial; Article; Bibliometrics; Databases, Bibliographic; Human; Humans; Information Storage and Retrieval; Medical Informatics; Poland; Priority journal; Randomized Controlled Trials as Topic; Utilization review -DOI: 10.1111/j.1471-1842.2007.00716.x -AB: BACKGROUND: The Polish Medical Bibliography (Polska Bibliografia Lekarska) contains 350 000 records dating from 1979. These records from the fields of medicine, nursing, dentistry, health care systems and preclinical sciences are from nearly 300 biomedical journals published in Poland. METHODS: We systematically searched the Polish Medical Bibliography Part II (1996‐2006) CD‐ROM (July 2006) using both English and Polish phrases for randomized trials, manually checked results and, for the trials identified in this way, sought these on medline and embase. RESULTS: Systematic searching identified records of 680 randomized trials from all areas of health care. Nearly 40% of these were not found on either medline or embase. CONCLUSIONS: The Polish Medical Bibliography should be of interest to health care information specialists concerned with comprehensive searches for trials. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01776192/full - - -Record #77 of 151 -ID: CN-01721989 -AU: Ewart R -AU: Lausen H -AU: Millian N -TI: Undisclosed changes in outcomes in randomized controlled trials: an observational study -SO: Annals of family medicine -YR: 2009 -VL: 7 -NO: 6 -PG: 542‐546 -PM: PUBMED 19901314 -XR: EMBASE 355763878 -PT: Journal article -KY: *Disclosure; *Publishing; *Randomized Controlled Trials as Topic; *outcomes research; *randomized controlled trial; Article; Bibliometrics; Clinical research; Cross‐sectional study; Endpoint Determination; Medical literature; Observational study; Publication; Registration; Registries; Retrospective study -DOI: 10.1370/afm.1017 -AB: PURPOSE: We wanted to investigate the frequency of undisclosed changes in the outcomes of randomized controlled trials (RCTs) between trial registration and publication. METHODS: Using a retrospective, nonrandom, cross‐sectional study design, we investigated RCTs published in consecutive issues of 5 major medical journals during a 6‐month period and their associated trials registry entries. Articles were excluded if they did not have an available trial registry entry, did not have analyzable outcomes, or were secondary publications. The primary outcome was the proportion of publications in which the primary outcome of the trial was, without disclosure, changed between that recorded in the trial registry and that reported in the final publication. The secondary outcome was the proportion of publications in which the secondary outcome was changed without disclosure. RESULTS: We reviewed 158 reports of RCTs and included 110 in the analysis. In 34 (31%), a primary outcome had been changed, and in 77 (70%), a secondary outcome had been changed. CONCLUSIONS: There are substantial and important undisclosed changes made to the outcomes of published RCTs between trial registration and publication. This finding has important implications for the interpretation of trial results. Disclosure and discussion of changes would improve transparency in the performance and reporting of trials. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01721989/full - - -Record #78 of 151 -ID: CN-01754169 -AU: Azar M -AU: Riehm KE -AU: McKay D -AU: Thombs BD -TI: Transparency of outcome reporting and trial registration of randomized controlled trials published in the journal of consulting and clinical psychology -SO: PloS one -YR: 2015 -VL: 10 -NO: 11 -PG: e0142894 -PM: PUBMED 26581079 -XR: EMBASE 608121424 -PT: Journal article -KY: *Bibliometrics; *Psychology, Clinical; *Randomized Controlled Trials as Topic; *clinical psychology; *registration; Attention; Behavioral medicine; Case report; Controlled clinical trial; Controlled study; Guidelines as Topic; Human; Humans; Intervention study; Outcome variable; Peer Review, Research; Practice guideline; Randomized controlled trial; Societies, Scientific -DOI: 10.1371/journal.pone.0142894 -AB: Background Confidence that randomized controlled trial (RCT) results accurately reflect intervention effectiveness depends on proper trial conduct and the accuracy and completeness of published trial reports. The Journal of Consulting and Clinical Psychology (JCCP) is the primary trials journal amongst American Psychological Association (APA) journals. The objectives of this study were to review RCTs recently published in JCCP to evaluate (1) adequacy of primary outcome analysis definitions; (2) registration status; and, (3) among registered trials, adequacy of outcome registrations. Additionally, we compared results from JCCP to findings from a recent study of top psychosomatic and behavioral medicine journals. Methods Eligible RCTs were published in JCCP in 2013‐2014. For each RCT, two investigators independently extracted data on (1) adequacy of outcome analysis definitions in the published report, (2) whether the RCT was registered prior to enrolling patients, and (3) adequacy of outcome registration. Results Of 70 RCTs reviewed, 12 (17.1%) adequately defined primary or secondary outcome analyses, whereas 58 (82.3%) had multiple primary outcome analyses without statistical adjustment or undefined outcome analyses. There were 39 (55.7%) registered trials. Only two trials registered prior to patient enrollment with a single primary outcome variable and time point of assessment. However, in one of the two trials, registered and published outcomes were discrepant. No studies were adequately registered as per Standard Protocol Items: Recommendation for Interventional Trials guidelines. Compared to psychosomatic and behavioral medicine journals, the proportion of published trials with adequate outcome analysis declarations was significantly lower in JCCP (17.1% versus 32.9%; p = 0.029). The proportion of registered trials in JCCP (55.7%) was comparable to behavioral medicine journals (52.6%; p = 0.709). Conclusions The quality of published outcome analysis definitions and trial registrations in JCCP is suboptimal. Greater attention to proper trial registration and outcome analysis definition in published reports is needed. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01754169/full - - -Record #79 of 151 -ID: CN-01763058 -AU: Rahman M -AU: Fukui T -TI: Geography of randomized controlled trials in general internal medicine: is the United States' share declining? -SO: American journal of medicine -YR: 2003 -VL: 114 -NO: 6 -PG: 510‐511 -PM: PUBMED 12727588 -XR: EMBASE 36515118 -PT: Journal article -KY: *clinical research; *internal medicine; *randomized controlled trial; Bibliometrics; Clinical trial; Controlled clinical trial; Financial management; General practice; Geographic distribution; Humans; Internal Medicine [*trends]; Letter; Medical literature; Medline; Nonparametric test; Priority journal; Publication; Randomized Controlled Trials as Topic [*trends]; Statistical significance; United States -DOI: 10.1016/S0002-9343(03)00062-7 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01763058/full - - -Record #80 of 151 -ID: CN-02076734 -AU: Murray DM -AU: Taljaard M -AU: Turner EL -AU: George SM -TI: Essential Ingredients and Innovations in the Design and Analysis of Group-Randomized Trials -SO: Annual review of public health -YR: 2020 -VL: 41 -PG: 1‐19 -PM: PUBMED 31869281 -XR: EMBASE 630414838 -PT: Journal article -KY: Article; Bibliometrics; Controlled study; Group therapy; Human; Humans; Medical research; National Institutes of Health (U.S.); National health organization; Randomized Controlled Trials as Topic [*methods]; Randomized controlled trial; Research Design; United States -DOI: 10.1146/annurev-publhealth-040119-094027 -AB: This article reviews the essential ingredients and innovations in the design and analysis of group‐randomized trials. The methods literature for these trials has grown steadily since they were introduced to the biomedical research community in the late 1970s, and we summarize those developments. We review, in addition to the group‐randomized trial, methods for two closely related designs, the individually randomized group treatment trial and the stepped‐wedge group‐randomized trial. After describing the essential ingredients for these designs, we review the most important developments in the evolution of their methods using a new bibliometric tool developed at the National Institutes of Health. We then discuss the questions to be considered when selecting from among these designs or selecting the traditional randomized controlled trial. We close with a review of current methods for the analysis of data from these designs, a case study to illustrate each design, and a brief summary. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02076734/full - - -Record #81 of 151 -ID: CN-00890480 -AU: Altman DG -TI: Endorsement of the CONSORT statement by high impact medical journals: survey of instructions for authors -SO: BMJ (Clinical research ed.) -YR: 2005 -VL: 330 -NO: 7499 -PG: 1056‐1057 -PM: PUBMED 15879389 -XR: EMBASE 40646557 -PT: Journal article -KY: *medical literature; Article; Authorship; Bibliometrics; Clinical trial; Controlled clinical trial; Data base; Electronics; Guidelines as Topic; Methodology; Periodicals as Topic [*standards]; Practice guideline; Priority journal; Publication; Randomized Controlled Trials as Topic [methods, *standards]; Randomized controlled trial -DOI: 10.1136/bmj.330.7499.1056 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-00890480/full - - -Record #82 of 151 -ID: CN-01753384 -AU: Nieri M -AU: Clauser C -AU: Franceschi D -AU: Pagliaro U -AU: Saletta D -AU: Pini-Prato G -TI: Randomized clinical trials in implant therapy: relationships among methodological, statistical, clinical, paratextual features and number of citations -SO: Clinical oral implants research -YR: 2007 -VL: 18 -NO: 4 -PG: 419‐431 -PM: PUBMED 17517060 -XR: EMBASE 47152711 -PT: Journal article -KY: *bibliometrics; *dental research; *randomized controlled trial; *tooth implantation; Algorithm; Algorithms; Article; Bayes Theorem; Bayes theorem; Bibliometrics; Data Interpretation, Statistical; Dental Implantation, Endosseous; Dental Implants; Dental Research [*methods]; Evaluation study; Human; Humans; Linear Models; Methodology; Observer Variation; Observer variation; Publishing; Randomized Controlled Trials as Topic [*methods]; Research Design; Statistical analysis; Statistical model -DOI: 10.1111/j.1600-0501.2007.01350.x -AB: OBJECTIVES: The aim of the present study was to investigate the relationships among reported methodological, statistical, clinical and paratextual variables of randomized clinical trials (RCTs) in implant therapy, and their influence on subsequent research. MATERIALS AND METHODS: The material consisted of the RCTs in implant therapy published through the end of the year 2000. Methodological, statistical, clinical and paratextual features of the articles were assessed and recorded. The perceived clinical relevance was subjectively evaluated by an experienced clinician on anonymous abstracts. The impact on research was measured by the number of citations found in the Science Citation Index. A new statistical technique (Structural learning of Bayesian Networks) was used to assess the relationships among the considered variables. RESULTS: Descriptive statistics revealed that the reported methodology and statistics of RCTs in implant therapy were defective. Follow‐up of the studies was generally short. The perceived clinical relevance appeared to be associated with the objectives of the studies and with the number of published images in the original articles. The impact on research was related to the nationality of the involved institutions and to the number of published images. CONCLUSIONS: RCTs in implant therapy (until 2000) show important methodological and statistical flaws and may not be appropriate for guiding clinicians in their practice. The methodological and statistical quality of the studies did not appear to affect their impact on practice and research. Bayesian Networks suggest new and unexpected relationships among the methodological, statistical, clinical and paratextual features of RCTs. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01753384/full - - -Record #83 of 151 -ID: CN-01776672 -AU: Lui S -AU: Smith EJ -AU: Terplan M -TI: Heterogeneity in search strategies among Cochrane acupuncture reviews: is there room for improvement? -SO: Acupuncture in medicine -YR: 2010 -VL: 28 -NO: 3 -CC: Complementary Medicine -PG: 149‐153 -PM: PUBMED 20615852 -XR: EMBASE 359890606 -PT: Journal article -KY: *acupuncture; *bibliographic database; *bibliometrics; *evidence based medicine; *information retrieval; *literature; Acupuncture Therapy [standards]; Article; Bibliometrics; Databases, Bibliographic [standards]; Evidence‐Based Medicine; Human; Humans; Information Storage and Retrieval [*methods, standards]; Language; Meta analysis; Meta‐Analysis as Topic; Methodology; Peer Review; Peer review; Randomized Controlled Trials as Topic; Randomized controlled trial; Research Design; Review Literature as Topic; Standard -DOI: 10.1136/aim.2010.002444 -AB: OBJECTIVE: Given the international focus and rigorous literature searches employed in Cochrane systematic reviews, this study was undertaken to evaluate strategies employed in Cochrane reviews and protocols assessing acupuncture as a primary or secondary intervention. METHODS: The Cochrane Collaboration of systematic reviews was searched in February 2009 for all reviews and protocols including information on acupuncture. Information was abstracted from all retrieved articles on review status, type and number of English and Chinese language databases searched, participation of at least one Chinese speaking author and language restriction. Frequencies were calculated and bivariate analyses were performed stratifying on interventions of interest to assess differences in search strategy techniques, language restrictions and results. RESULTS: The search retrieved 68 titles, including 48 completed reviews, 17 protocols and three previously withdrawn titles. Acupuncture was the primary intervention of interest in 44/65 (67.7%) of the retrieved reviews and protocols. While all articles searched at least one English language database, only 26/65 (40.0%) articles searched Chinese language databases. Significantly more articles where acupuncture was the primary intervention of interest searched Chinese language databases (53% vs 9%, p<0.01). Inconclusive findings as to the effectiveness of acupuncture were found in 28/48 (58.3%) of all completed reviews; this type of finding was more common in reviews which did not search any Chinese language databases. CONCLUSIONS: It is important for reviews assessing the effectiveness of acupuncture to search Chinese language databases. The Cochrane Collaboration should develop specific criteria for Chinese language search strategies to ensure the continued publication of high‐quality reviews. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01776672/full - - -Record #84 of 151 -ID: CN-01725964 -AU: Mao B -AU: Wang G -AU: Fan T -TI: Change and trend of disease spectrum in randomized controlled trials of traditional Chinese medicine -SO: Zhongguo zhong xi yi jie he za zhi zhongguo zhongxiyi jiehe zazhi = chinese journal of integrated traditional and western medicine -YR: 2007 -VL: 27 -NO: 5 -PG: 404‐408 -PM: PUBMED 17650791 -XR: EMBASE 350354609 -PT: Journal article -KY: *Chinese medicine; *phytotherapy; *randomized controlled trial; Article; Bibliometrics; Cardiovascular Diseases [drug therapy]; Cardiovascular disease /drug therapy; Drugs, Chinese Herbal [*therapeutic use]; Evidence based medicine; Evidence‐Based Medicine; Human; Humans; Medicine, Chinese Traditional [*methods]; Methodology; Neoplasm /drug therapy; Neoplasms [drug therapy]; Periodicals as Topic [standards]; Phytotherapy; Publication; Randomized Controlled Trials as Topic; Standard -AB: OBJECTIVE: To investigate the spectral changes of diseases with the treatment of traditional Chinese medicine (TCM), and to find out the advantages of TCM. METHODS: A manual search for papers of randomized controlled trials (RCTs) in 13 core journals of TCM and integrated Chinese and Western medicine (ICWM) published from 1999 to 2004 were performed to create a database of RCTs. Depending on the database, the diseases involved were classified systematically. Among them, the common diseases were analyzed, and the disease spectrum was compared with that gotten from the RCTs database founded from 1980 ‐ 1998. RESULTS: Most of the total 7 422 articles on RCTs enclosed were concerning the diseases of digestive system (14.93%), cardiovascular system (11.33%), nervous system (10.01%), and respiratory system (8.68%), and mostly were studies on cerebrovascular accident, diabetes mellitus, coronary heart disease (CHD) and chronic obstructive pulmonary disease, accounting for 5.01%, 4.86%, 3.17% and 2.57%, respectively. As compared with the previous materials, the constituent ratios of nervous system disease, endocrine metabolic disease, tumor, and gynopathy from 1999 to 2004 were raised (all P <0.05), while those of digestive and respiratory system diseases were lowered (both P < 0.05). CONCLUSION: Researchers of TCM and ICWM pay more attention to the clinical studies about prevention and treatment with TCM on cerebro‐/cardiovascular disease, endocrine metabolic disease and malignant tumor. TCM possesses advantages in treating chronic disease, preventing disease, emphasizing on wholism and is economic with fewer adverse reactions. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01725964/full - - -Record #85 of 151 -ID: CN-01773447 -AU: Mistiaen P -AU: Poot E -AU: Hickox S -AU: Wagner C -TI: The evidence for nursing interventions in the Cochrane Database of Systematic Reviews -SO: Nurse researcher -YR: 2004 -VL: 12 -NO: 2 -PG: 71‐80 -PM: PUBMED 15636007 -XR: EMBASE 40257614 -PT: Journal article -KY: *bibliographic database; *literature; *nursing research; Article; Bibliometrics; Clinical trial; Controlled clinical trial; Databases, Bibliographic [*standards]; Evidence based medicine; Evidence‐Based Medicine; Human; Humans; Information Services [standards]; Information service; Methodology; Nursing Research [*organization & administration]; Organization and management; Practice Guidelines as Topic; Practice guideline; Randomized Controlled Trials as Topic [standards]; Randomized controlled trial; Research Design [standards]; Review Literature as Topic; Standard -AB: In this paper, Patriek Mistiaen, Else Poot, Sophie Hickox, and Cordula Wagner describe how they conducted a search of the Cochrane Database of Systematic Reviews in order to explore the evidence for nursing interventions. They identify the number of studies, the number of participants, and the conclusions of systematic reviews concerning nursing interventions. They conclude that the Cochrane Database of Systematic Reviews is a valuable source of evidence about nursing interventions, and can be used as a means of developing a research agenda in the case of inconclusive reviews. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01773447/full - - -Record #86 of 151 -ID: CN-01746627 -AU: Sandercock P -AU: Fraser H -AU: Thomas B -AU: McInnes A -AU: Dixon S -TI: Cochrane Stroke Group 10 years on: progress to date and future challenges -SO: Stroke -YR: 2003 -VL: 34 -NO: 10 -PG: 2537‐2539 -PM: PUBMED 14500941 -XR: EMBASE 37349596 -PT: Journal article -KY: *cerebrovascular accident /diagnosis /therapy; *cooperation; *factual database; Article; Bibliometrics; Biomedical Research; Clinical trial; Controlled Clinical Trials as Topic [statistics & numerical data, trends]; Controlled clinical trial; Cooperative Behavior; Databases, Factual [*statistics & numerical data, trends]; Guidelines as Topic; Human; Humans; International Cooperation; International cooperation; Literature; Medical research; Practice guideline; Randomized Controlled Trials as Topic [statistics & numerical data, trends]; Randomized controlled trial; Register; Registries [statistics & numerical data]; Review Literature as Topic; Statistics; Stroke [*diagnosis, *therapy] -DOI: 10.1161/01.STR.0000089016.77502.59 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01746627/full - - -Record #87 of 151 -ID: CN-01730071 -AU: Li N -AU: Xie ZF -TI: Preliminary analysis on the method of efficacy evaluation used in clinical articles issued in Chinese journal of integrated traditional and Western medicine -SO: Zhongguo zhong xi yi jie he za zhi zhongguo zhongxiyi jiehe zazhi = chinese journal of integrated traditional and western medicine -YR: 2004 -VL: 24 -NO: 1 -PG: 72‐74 -PM: PUBMED 14976898 -XR: EMBASE 38894107 -PT: Journal article -KY: *Chinese medicine; *bibliometrics; *phytotherapy; Article; Bibliometrics; Clinical trial; Controlled clinical trial; Double blind procedure; Double‐Blind Method; Drugs, Chinese Herbal [*therapeutic use]; Evaluation Studies as Topic; Evaluation study; Human; Humans; Medicine, Chinese Traditional; Methodology; Periodicals as Topic; Phytotherapy; Publication; Randomized Controlled Trials as Topic [methods]; Randomized controlled trial -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01730071/full - - -Record #88 of 151 -ID: CN-02361346 -AU: Murray DM -TI: Influential methods reports for group-randomized trials and related designs -SO: Clinical trials (London, England) -YR: 2022 -VL: 19 -NO: 4 -PG: 353‐362 -PM: PUBMED 34991379 -XR: EMBASE 2014685939 -PT: Journal article -KY: *Research Design; *Research Report; *group therapy; Analytic method; Article; Attention; Bibliometrics; Calculation; Controlled study; Data Collection; Human; Humans; Implementation science; Medline; National health organization; Randomized Controlled Trials as Topic; Randomized controlled trial (topic); Sample Size; Sample size; Systematic review -DOI: 10.1177/17407745211063423 -AB: Background. This article identifies the most influential methods reports for group‐randomized trials and related designs published through 2020. Many interventions are delivered to participants in real or virtual groups or in groups defined by a shared interventionist so that there is an expectation for positive correlation among observations taken on participants in the same group. These interventions are typically evaluated using a group‐ or cluster‐randomized trial, an individually randomized group treatment trial, or a stepped wedge group‐ or cluster‐randomized trial. These trials face methodological issues beyond those encountered in the more familiar individually randomized controlled trial. Methods. PubMed was searched to identify candidate methods reports; that search was supplemented by reports known to the author. Candidate reports were reviewed by the author to include only those focused on the designs of interest. Citation counts and the relative citation ratio, a new bibliometric tool developed at the National Institutes of Health, were used to identify influential reports. The relative citation ratio measures influence at the article level by comparing the citation rate of the reference article to the citation rates of the articles cited by other articles that also cite the reference article. Results. In total, 1043 reports were identified that were published through 2020. However, 55 were deemed to be the most influential based on their relative citation ratio or their citation count using criteria specific to each of the three designs, with 32 group‐randomized trial reports, 7 individually randomized group treatment trial reports, and 16 stepped wedge group‐randomized trial reports. Many of the influential reports were early publications that drew attention to the issues that distinguish these designs from the more familiar individually randomized controlled trial. Others were textbooks that covered a wide range of issues for these designs. Others were “first reports” on analytic methods appropriate for a specific type of data (e.g. binary data, ordinal data), for features commonly encountered in these studies (e.g. unequal cluster size, attrition), or for important variations in study design (e.g. repeated measures, cohort versus cross‐section). Many presented methods for sample size calculations. Others described how these designs could be applied to a new area (e.g. dissemination and implementation research). Among the reports with the highest relative citation ratios were the CONSORT statements for each design. Conclusions. Collectively, the influential reports address topics of great interest to investigators who might consider using one of these designs and need guidance on selecting the most appropriate design for their research question and on the best methods for design, analysis, and sample size. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02361346/full - - -Record #89 of 151 -ID: CN-01765189 -AU: Scholes J -TI: Research in Nursing in Critical Care 1995-2009: a cause for celebration -SO: Nursing in critical care -YR: 2010 -VL: 15 -NO: 1 -PG: 20‐25 -PM: PUBMED 20070811 -XR: EMBASE 358572232 -PT: Journal article -KY: *bibliometrics; *intensive care; *methodology; *nursing discipline; *nursing research; *publication; Article; Authorship; Bibliometrics; Critical Care [trends]; Ethics; Human; Humans; Literature; Nursing Research [*trends]; Periodicals as Topic [ethics, *trends]; Publishing; Publishing [ethics, trends]; Qualitative Research; Qualitative research; Randomized Controlled Trials as Topic [trends]; Randomized controlled trial; Research Design [*trends]; Review Literature as Topic; Specialties, Nursing [trends]; United Kingdom; Writing -DOI: 10.1111/j.1478-5153.2009.00377.x -AB: AIM: The purpose of this article is to analyse the research papers published in Nursing in Critical Care (n = 168) over the past 15 years to examine trends in methodology, theoretical contribution and authorship. BACKGROUND: Research is a contested term and the paper starts with defining the criteria by which papers were selected for the review. METHODS: The approach undertaken was a documentary review based on an adaptation of Schatzman's dimensional analysis. Papers were loaded into a matrix then categorized and grouped to determine trends and frequency. CONCLUSION: Research papers published in the journal reflect a wide range of interests and broad spread of research methods. Qualitative and quantitative data are used by authors but to distinguish papers into these two categories would be over simplistic. Systematic reviews along with randomized control trials and studies using a quasi‐experimental design are the least frequently occurring approaches in the published papers, although they are growing in number in recent years. All the papers make explicit the implications for clinical practice and as such contribute to the growing body of knowledge to inform critical care nursing practice. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01765189/full - - -Record #90 of 151 -ID: CN-02635632 -AU: Hawk LW -AU: Murphy TF -AU: Hartmann KE -AU: Burnett A -AU: Maguin E -TI: A randomized controlled trial of a team science intervention to enhance collaboration readiness and behavior among early career scholars in the Clinical and Translational Science Award network -SO: Journal of clinical and translational science -YR: 2024 -VL: 8 -NO: 1 -XR: EMBASE 2029123145 -PT: Journal article -KY: *career; Adult; Article; Benchmarking; Bibliometrics; Controlled study; Follow up; Human; Intention to treat analysis; Male; Randomized controlled trial; Therapy; Translational science -DOI: 10.1017/cts.2023.692 -AB: Introduction: Despite the central importance of cross‐disciplinary collaboration in the Clinical and Translational Science Award (CTSA) network and the implementation of various programs designed to enhance collaboration, rigorous evidence for the efficacy of these approaches is lacking. We conducted a novel randomized controlled trial (RCT; ClinicalTrials.gov identifier: NCT05395286) of a promising approach to enhance collaboration readiness and behavior among 95 early career scholars from throughout the CTSA network. Methods: Participants were randomly assigned (within two cohorts) to participate in an Innovation Lab, a week‐long immersive collaboration experience, or to a treatment‐as‐usual control group. Primary outcomes were change in metrics of self‐reported collaboration readiness (through 12‐month follow‐up) and objective collaboration network size from bibliometrics (through 21 months); secondary outcomes included self‐reported number of grants submitted and, among Innovation Lab participants only, reactions to the Lab experience (through 12 months). Results: Short‐term reactions from Innovation Lab participants were quite positive, and controlled evidence for a beneficial impact of Innovation Labs over the control condition was observed in the self‐reported number of grant proposals in the intent‐to‐treat sample. Primary measures of collaboration readiness were near ceiling in both groups, limiting the ability to detect enhancement. Collaboration network size increased over time to a comparable degree in both groups. Conclusions: The findings highlight the need for systematic intervention development research to identify efficacious strategies that can be implemented throughout the CTSA network to better support the goal of enhanced cross‐disciplinary collaboration. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02635632/full - - -Record #91 of 151 -ID: CN-01977849 -AU: Sebo P -AU: Fournier JP -AU: Maisonneuve H -TI: Is statistician involvement as co-author associated with reduced time to publication of quantitative research in general medical journals? A bibliometric study -SO: Family practice -YR: 2019 -VL: 36 -NO: 4 -PG: 431‐436 -PM: PUBMED 30476030 -XR: EMBASE 628973946 -PT: Journal article -KY: *publication; *retrospective study; *statistician; *velocity; Article; Authorship; Bibliometrics; Biomedical Research [*trends]; Controlled study; Human; Human experiment; Humans; Internal Medicine; Internal medicine; Periodicals as Topic; Primary medical care; Qualitative Research; Qualitative research; Questionnaire; Randomized controlled trial; Retrospective Studies; Statistical significance; Statistics as Topic; Time Factors -DOI: 10.1093/fampra/cmy115 -AB: OBJECTIVE: We aimed to compare the number of submissions until acceptance and the time to publication between articles co‐authored and articles not co‐authored by statisticians. METHODS: We randomly selected 781 articles published in 2016 in 18 high impact factor journals of general internal medicine and primary care. For each article, we retrieved its date of submission to the journal and its first publication; we also contacted its corresponding author and asked about the number of submissions necessary from the first submission to a journal until acceptance and whether the article was co‐authored by a statistician. After having excluded qualitative studies, we compared the articles co‐authored with those not co‐authored by statisticians in terms of number of submissions and submission‐to‐publication time, using negative binomial and Cox regressions, adjusted for intracluster correlations. RESULTS: One hundred fifty‐eight authors completed the questionnaire (20%); 136 articles with quantitative design were included in the study. Overall, 63 articles (46%) were co‐authored by statisticians. There was no statistically significant difference in the number of submissions (statistician group: mean 2.1 (SD 1.1) versus 2.2 (SD 1.2), P value 0.87). By contrast, we found a statistically significant difference in the submission‐to‐publication time (statistician group: median 211 days [interquartile range (IQR) 171] versus 260 (IQR 144); hazard ratio 1.44 (95% CI 1.01‐2.03), adjusted P value 0.04). CONCLUSIONS: Papers co‐authored by statisticians have a shorter time to publication. We encourage researchers to closely involve statisticians in the design, conduct and statistical analysis of research, not only to ensure high standards of quality but also to speed up its publication. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01977849/full - - -Record #92 of 151 -ID: CN-02636338 -AU: Ang L -AU: Song E -AU: Lee MS -TI: Randomized controlled trials of traditional, complementary, and integrative medicine-based interventions for coronavirus disease 2019 (COVID-19): a bibliometric analysis and review of study designs -SO: Integrative medicine research -YR: 2021 -VL: 10 -NO: Suppl -PG: 100777 -PM: PUBMED 34580628 -PT: Journal article -DOI: 10.1016/j.imr.2021.100777 -AB: BACKGROUND: To date, the coronavirus disease 2019 (COVID‐19) pandemic remains ongoing and continues to affect millions of people worldwide. In the effort of fighting this pandemic, there has been an increasing interest in the potential of traditional, complementary, and integrative medicines (TCIMs) in engaging COVID‐19. This study presents a bibliometric analysis of the research trends of TCIMs for COVID‐19. METHODS: Six databases were searched on July 15, 2021, to retrieve all the citations on TCIM‐focused randomized controlled trials (RCTs) available on COVID‐19. Only RCTs that mentioned at least one TCIMs for the treatment and/or management or COVID‐19 were eligible. Data such as number and countries of trials conducted, publication journal, research focus, study design, and sample size were extracted for analysis. RESULTS: The resulting 56 articles were authored by 553 unique authors, and included 28 English articles, 19 Chinese articles with English abstracts, and 9 Chinese articles without English abstract. Analyses had shown that China was the dominant country with TCIM related RCT publications, followed by India and the United States. The included articles were published across 24 English journals and 22 Chinese journals with a wide range of impact factors from 0.220 to 56.272. The most commonly studied TCIM modalities included Chinese herbal decoction (n=12) and Chinese patent medicine (n=16). In terms of study designs, TCIM interventions were integrated with standard medicine across the trials with most trials having a small to medium sample size and open‐labeled. CONCLUSION: This bibliometric analysis of RCTs demonstrated the research trends and characteristics of TCIM utilized in COVID‐19 research. Although there are still many research gaps and limitations for pandemic research, the publication of TCIM‐focused RCTs is anticipated to show a continuously increasing trend. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02636338/full - - -Record #93 of 151 -ID: CN-02142481 -AU: Noguchi Y -AU: Kaneko M -AU: Narukawa M -TI: Characteristics of Drug Intervention Clinical Trials and Scientific Impact of the Trial Outcome: a Bibliometric Analysis Using the Relative Citation Ratio in Non-small Cell Lung Cancer from 2007 to 2016 -SO: Therapeutic innovation & regulatory science -YR: 2020 -VL: 54 -NO: 6 -PG: 1501‐1511 -PM: PUBMED 32529630 -XR: EMBASE 2005221052 -PT: Journal article -KY: *evidence based medicine; *non small cell lung cancer; Adult; Article; Bibliometrics; Cancer chemotherapy; Carcinoma, Non‐Small‐Cell Lung [drug therapy]; Controlled study; Female; Human; Humans; Lung Neoplasms [drug therapy]; Male; National health organization; Pharmaceutical Preparations; Phase 3 clinical trial; Profit; Protein Kinase Inhibitors; Randomized controlled trial; Single blind procedure; United States -DOI: 10.1007/s43441-020-00177-5 -AB: Background: Although a large number of clinical trials have been conducted, the types of clinical trials that are scientifically influential, frequently utilized by society, and contribute to the progress of evidence‐based medicine (EBM) have not been studied. Thus, we aimed to investigate the relationship between the characteristics of clinical trials and the scientific impact of the outcome in non‐small cell lung cancer (NSCLC) by performing a bibliometric analysis using relative citation ratio (RCR), a newly developed bibliometric index by the National Institutes of Health (NIH). Methods: Primary publications of drug intervention clinical trials for NSCLC between 2007 and 2016 were included in the study. The characteristics of clinical trials were compared among four RCR categories with 50 trials in each [LOW50, 50 NIH percentile (50NIH%ile), 95 NIH percentile (95NIH%ile), and TOP50], totaling to 200 trials. Results: Median RCRs of LOW50, 50NIH%ile, 95NIH%ile, and TOP50 were 0.03, 1.00, 5.76, and 26.89, respectively. Publications of Phase 3, randomized, blinded, for‐profit‐company supported/sponsored, multi‐center trials, and trials with a larger number of subjects were shown to have a higher scientific impact. Publications of clinical trials of newly developed molecular target drugs, including epidermal growth factor receptor‐tyrosine kinase inhibitors, anaplastic lymphoma kinase inhibitors, and immune checkpoint inhibitors demonstrated a higher scientific impact than those of traditional chemotherapies. Conclusion: Clinical trials designed to have a high evidence level would improve the scientific impact of the outcome, and novel interventions would be another factor to improve the clinical trials’ influence. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02142481/full - - -Record #94 of 151 -ID: CN-01666915 -AU: Balbuena LD -TI: The UK Research Excellence Framework and the Matthew effect: insights from machine learning -SO: PloS one -YR: 2018 -VL: 13 -NO: 11 -PG: e0207919 -PM: PUBMED 30475868 -XR: EMBASE 625190226 -PT: Journal article -KY: *machine learning; Article; Bayes Theorem; Bibliometrics; Controlled study; Educational Measurement; Explanatory variable; Human; Humans; Machine Learning; Major clinical study; Models, Theoretical; Randomized controlled trial; Research; Scholarly Communication; Student; Students; United Kingdom; Universities [economics]; Web of Science -DOI: 10.1371/journal.pone.0207919 -AB: With the high cost of the research assessment exercises in the UK, many have called for simpler and less time‐consuming alternatives. In this work, we gathered publicly available REF data, combined them with library‐subscribed data, and used machine learning to examine whether the overall result of the Research Excellence Framework 2014 could be replicated. A Bayesian additive regression tree model predicting university grade point average (GPA) from an initial set of 18 candidate explanatory variables was developed. One hundred and nine universities were randomly divided into a training set (n = 79) and test set (n = 30). The model "learned" associations between GPA and the other variables in the training set and was made to predict the GPA of universities in the test set. GPA could be predicted from just three variables: the number of Web of Science documents, entry tariff, and percentage of students coming from state schools (r‐squared = .88). Implications of this finding are discussed and proposals are given. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01666915/full - - -Record #95 of 151 -ID: CN-02096737 -AU: Bianchini C -AU: Cosentino C -AU: Paci M -AU: Baccini M -TI: Open Access Physical Therapy Journals: do Predatory Journals Publish Lower-Quality Randomized Controlled Trials? -SO: Archives of physical medicine and rehabilitation -YR: 2020 -VL: 101 -NO: 6 -PG: 969‐977 -PM: PUBMED 32001256 -XR: EMBASE 2005067684 -PT: Journal article -KY: *peer review; *physiotherapy; Article; Bibliometrics; Clinical article; Controlled study; Directory; Human; Humans; Independent variable; Medline; Outcome assessment; PEDro; Peer Review, Research [*standards]; Periodicals as Topic [*standards]; Physical Therapy Modalities; Publishing [*standards]; Randomized Controlled Trials as Topic [*standards]; Randomized controlled trial -DOI: 10.1016/j.apmr.2019.12.012 -AB: OBJECTIVES: To compare the quality of randomized controlled trials (RCTs) published in predatory and nonpredatory journals in the field of physical therapy. DATA SOURCES: From a list of 18 journals included either on Beall's list (n=9) or in the Directory of Open Access Journals (DOAJ) (n=9), 2 independent assessors extracted all the RCTs published between 2014 and 2017. When journals published more than 40 RCTs, a sample of 40 trials was randomly extracted, preserving the proportions among years. Indexing in PubMed, country of journal publication, and dates of submission or acceptance were also recorded for each journal. MAIN OUTCOME MEASURES: The PEDro (Physiotherapy Evidence Database) scale and duration of the peer review. RESULTS: Four hundred ten RCTs were included. The mean PEDro score of articles published in non‐Beall, DOAJ journals was higher than those published in Beall journals (mean score ± SD, 5.8±1.7 vs 4.5±1.5; P<.001), with the differences increasing when the indexing in PubMed was also considered (6.5±1.5 vs 4.4±1.5; P<.001). The peer review duration was significantly longer in non‐Beall than in Beall journals (mean duration [d] ± SD, 145.2±92.9 vs 45.4±38.8; P<.001) and in journals indexed in PubMed than in nonindexed journals (136.6±100.7 vs 60.4±55.7; P<.001). Indexing in PubMed was the strongest independent variable associated with the PEDro score (adjusted R2=0.182), but noninclusion on Beall's list explained an additional, albeit small, portion of the PEDro score variance (cumulative adjusted R2=0.214). CONCLUSIONS: Potentially predatory journals publish lower‐quality trials and have a shorter peer review process than non‐Beall journals included in the DOAJ database. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02096737/full - - -Record #96 of 151 -ID: CN-01746539 -AU: Hopewell S -TI: Assessing the impact of abstracts from the Thoracic Society of Australia and New Zealand in Cochrane reviews -SO: Respirology (Carlton, Vic.) -YR: 2003 -VL: 8 -NO: 4 -PG: 509‐512 -PM: PUBMED 14629657 -XR: EMBASE 38009648 -PT: Journal article -KY: *Cochrane Library; *medical society; Article; Australia; Bibliometrics; Clinical trial; Congresses as Topic; Controlled clinical trial; Health care; Humans; Medical research; Methodology; New Zealand; Priority journal; Publication; Publication Bias; Randomized controlled trial; Respiratory Tract Diseases; Review Literature as Topic; Thoracic Diseases -DOI: 10.1046/j.1440-1843.2003.00508.x -AB: OBJECTIVE: The aim of this study was to assess the potential impact of including trials, reported in conference abstracts from the Thoracic Society of Australia and New Zealand, in Cochrane reviews. METHODOLOGY: Abstracts from the Thoracic Society of Australia and New Zealand, published in the Australian and New Zealand Journal of Medicine (1981‐1998), were read to identify all reports of randomized trials. A search was carried out of the Cochrane Database of Systematic Reviews (Issue 1, 2002) for each trial reported in a conference abstract to try to identify Cochrane reviews in which the conference abstract might be eligible for inclusion. If it was unclear, the authors of the review were contacted. RESULTS: A total of 187 reports of randomized trials were identified: 101 (54%) had been published as a full report and 86 (46%) remained unpublished. Thirty‐four (72%) were reports of randomized controlled trials and 52 (28%) were quasi‐randomized or possibly randomized trials. The total number of patients included in the trials was 9691; range 4‐1203 (median 20; IQR 11‐47). No possible Cochrane review was found for 145 of the 187 trials reported in the conference abstracts. Possible reviews were identified for 42 trials, 24 of which were already mentioned in Cochrane reviews. For the remaining 18 trials, only three were said to be eligible for inclusion. CONCLUSION: A search of conference abstracts identified a number of reports of randomized trials, potentially eligible for inclusion in reviews of health care. However, the majority of trials were not relevant for inclusion in an existing Cochrane review. This is most likely because there are currently too few reviews to deal with the topics covered in the abstracts. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01746539/full - - -Record #97 of 151 -ID: CN-01113240 -AU: Garfinkle M -AU: Stewart S -AU: Ward H -AU: Wilson T -TI: Publishing journal's prestige does not influence critical appraisal -SO: Journal of clinical epidemiology -YR: 2015 -VL: 68 -NO: 9 -PG: 1093‐1094 -PM: PUBMED 25293423 -PT: Journal article -KY: Bias; Bibliometrics; Humans; Internship and Residency; Periodicals as Topic; Publishing; Randomized Controlled Trials as Topic; Research Design; Surveys and Questionnaires -DOI: 10.1016/j.jclinepi.2014.09.009 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01113240/full - - -Record #98 of 151 -ID: CN-01775694 -AU: Kjaergard LL -AU: Gluud C -TI: Citation bias of hepato-biliary randomized clinical trials -SO: Journal of clinical epidemiology -YR: 2002 -VL: 55 -NO: 4 -PG: 407‐410 -PM: PUBMED 11927210 -XR: EMBASE 34240493 -PT: Journal article -KY: *hepatobiliary disease; Adult; Aged; Article; Bias; Bibliometrics; Biliary Tract Diseases; Clinical trial; Controlled clinical trial; Data base; Double‐Blind Method; Female; Human; Humans; Liver Diseases; MEDLINE; Major clinical study; Male; Medline; Meta analysis; Methodology; Outcomes research; Priority journal; Publication; Randomized Controlled Trials as Topic; Randomized controlled trial; Retrospective Studies; Statistical significance -DOI: 10.1016/S0895-4356(01)00513-3 -AB: The objective of this study was to assess whether trials with a positive (i.e., statistically significant) outcome are cited more often than negative trials. We reviewed 530 randomized clinical trials on hepato‐biliary diseases published in 11 English‐language journals indexed in MEDLINE from 1985‐1996. From each trial, we extracted the statistical significance of the primary study outcome (positive or negative), the disease area, and methodological quality (randomization and double blinding). The number of citations during two calendar years after publication was obtained from Science Citation Index. There was a significant positive association between a statistically significant study outcome and the citation frequency (beta, 0.55, 95% confidence interval, 0.39‐0.72). The disease area and adequate generation of the allocation sequence were also significant predictors of the citation frequency. We concluded that positive trials are cited significantly more often than negative trials. The association was not explained by disease area or methodological quality. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01775694/full - - -Record #99 of 151 -ID: CN-02295250 -AU: Su X -AU: Hu HY -AU: Xu C -TI: Global Research on Neuropathic Pain Rehabilitation over the Last 20 Years -SO: Neural plasticity -YR: 2021 -VL: 2021 -PG: 5594512 -PM: PUBMED 34306062 -XR: EMBASE 2013723610 -PT: Journal article -KY: *Bibliometrics; *neuropathic pain /rehabilitation; Academies and Institutes [statistics & numerical data]; Authorship; Exercise; Global Health; Human; Humans; Linear regression analysis; Neuralgia [*rehabilitation]; Periodicals as Topic [statistics & numerical data]; Questionnaire; Rehabilitation research; Research [*trends]; Review; Software; United States -DOI: 10.1155/2021/5594512 -AB: Background. Neuropathic pain has long been a very popular and productive field of clinical research. Neuropathic pain is difficult to cure radically because of its complicated etiology and uncertain pathogenesis. As pain worsens and persists, pain recovery techniques become more important, and medication alone is insufficient. No summary of bibliometric studies on neuropathic pain rehabilitation is yet available. The purpose of the present study is to analyze in a systematic manner the trends of neuropathic pain rehabilitation research over the period of 2000‐2019. Methods. Studies related to neuropathic pain rehabilitation and published between January 2000 and December 2019 were obtained from the Science Citation Index‐Expanded of Web of Science. No restrictions on language, literature type, or species were established. CiteSpace V and Microsoft Excel were used to capture basic information and highlights in the field. Results. Linear regression analysis showed that the number of publications on neuropathic pain rehabilitation significantly increased over time (P<0.001). The United States showed absolute strength in terms of number of papers published, influence, and cooperation with other countries. Based on the subject categories of the Web of Science, "Rehabilitation"had the highest number of published papers (446), the highest number of citations (10,954), and the highest number of open‐access papers (151); moreover, this category and "Clinical Neurology"had the same H‐index (i.e., 52). "Randomized Controlled Trials"revealed the largest cluster in the cocitation map of references. The latest burst keywords included "Exercise"(2014‐2019), "Functional Recovery"(2015‐2019), and "Questionnaire"(2015‐2019). Conclusion. This study provides valuable information for neuropathic pain rehabilitation researchers seeking fresh viewpoints related to collaborators, cooperative institutions, and popular topics in this field. Some new research trends are also highlighted. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02295250/full - - -Record #100 of 151 -ID: CN-02175827 -AU: Polce EM -AU: Kunze KN -AU: Farivar D -AU: Fu MC -AU: Nwachukwu BU -AU: Nho SJ -AU: Chahla J -TI: Orthopaedic Randomized Controlled Trials Published in General Medical Journals Are Associated With Higher Altmetric Attention Scores and Social Media Attention Than Nonorthopaedic Randomized Controlled Trials -SO: Arthroscopy -YR: 2021 -VL: 37 -NO: 4 -PG: 1261‐1270 -PM: PUBMED 32956804 -XR: EMBASE 632945918 -PT: Journal article -KY: *Bibliometrics; *Orthopedics; *Periodicals as Topic; *Randomized Controlled Trials as Topic; *Social Media; *attention; *social media; Article; Bias; Controlled study; Human; Humans; Information center; Internal medicine; Journal Impact Factor; Linear Models; Linear regression analysis; Medical society; Orthopedic Procedures; Orthopedic surgeon; Randomized controlled trial; United States -DOI: 10.1016/j.arthro.2020.09.015 -AB: PURPOSE: To (1) compare the Altmetric Attention Score (AAS) and citation rates between orthopaedic and nonorthopaedic randomized controlled trials (RCTs) from 5 high‐impact medical journals and (2) identify general characteristics of these articles associated with greater exposure on social media platforms. METHODS: Articles published in The New England Journal of Medicine (NEJM), Lancet, The Journal of the American Medical Association (JAMA), Annals of Internal Medicine, and Archives of Internal Medicine between January 2011 and December 2016 were analyzed. These journals were selected based on retaining high impact factors with rigorous publication standards and availability of the AAS for their publications. The queried time frame was chosen to balance the inception of the AAS with an optimal period for citation accrual. A total of 14 article characteristics, in addition to number of Tweets, Facebook shares, news mentions, and the AAS, were extracted. Inclusion criteria were orthopaedic RCTs reporting on outcomes after surgical intervention. Linear regression was used to assess the relationship between publication characteristics and the AAS and social media attention. RESULTS: A total of 9 orthopaedic and 59 nonorthopaedic RCTs were included. The mean AASs were significantly different (574 ± 565.7 versus 256.9 ± 222.3, P = .003), whereas citation rate was not (192.2 ± 117.1 versus 382.3 ± 560.3, P = .317). Orthopaedic RCTs had a significantly greater number of mentions on Twitter and Facebook (P < .001). A higher AAS significantly associated with a greater number of citations (β = 0.75, P = .019) for orthopaedic RCTs. The mean AAS of orthopaedic RCTs favoring nonoperative management (809.6 ± 676.3) was greater than those favoring operative treatment (292.0 ± 248.9) but was not statistically significant (P = .361). CONCLUSION: Orthopaedic RCTs published in 5 high‐impact general medical journals had a significantly greater mean AAS relative to nonorthopaedic RCTs, with no differences in citation rates. Additionally, there was a strong association between the AAS and citation rate of orthopaedic RCTs. Orthopaedic RCTs had greater social media exposure on both Twitter and Facebook. CLINICAL RELEVANCE: Orthopaedic surgeons, researchers, and providers who publish RCTs in high‐impact medical journals can anticipate extensive social media attention for their articles relative to other nonorthopaedic RCTs in the same journals. Social media attention may be related to operative versus nonoperative management topics. This study provides further evidence for the increasing use of the AAS and its association with citation accrual. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02175827/full - - -Record #101 of 151 -ID: CN-01782017 -AU: Ramasubbu K -AU: Gurm H -AU: Litaker D -TI: Gender bias in clinical trials: do double standards still apply? -SO: Journal of women's health & gender-based medicine -YR: 2001 -VL: 10 -NO: 8 -PG: 757‐764 -PM: PUBMED 11703888 -XR: EMBASE 33062085 -PT: Journal article -KY: *clinical research; Adult; Analysis of Variance; Article; Bibliometrics; Clinical observation; Clinical study; Clinical trial; Controlled clinical trial; Controlled study; Data analysis; Female; Financial management; Health care policy; Health status; Human; Humans; Major clinical study; Male; Medical information; Medical literature; Medicine; Mortality; Patient Selection; Patient selection; Performance; Phase 3 clinical trial; Prejudice; Priority journal; Publication; Randomized Controlled Trials as Topic [*trends]; Randomized controlled trial; Sex difference; Specialization; Standard; United States -DOI: 10.1089/15246090152636514 -AB: Differential enrollment into clinical trials by gender has been described previously. In 1993, the National Institutes of Health (NIH) Revitalization Act was enacted to promote the inclusion of women in clinical trials. The purpose of this study was to review patterns in clinical trial enrollment among studies published in a major medical journal to determine the effects of this policy. A systematic search was conducted of all articles published in the Original Articles section of The New England Journal of Medicine from 1994 to 1999. Two independent observers abstracted information from the randomized clinical trials using standardized forms. All randomized clinical trials in which the primary end point was total mortality or included mortality in a composite end point were considered for review. Trials were analyzed for enrollment of women with respect to disease state, funding source, site of trial performance, and use of gender‐specific data analysis. From 1994 to 1999, 1322 original articles were published in The New England Journal of Medicine, including 442 randomized, controlled trials of which 120 met our inclusion criteria. On average, 24.6% women were enrolled. Gender‐specific data analysis was performed in 14% of the trials. The NIH Revitalization Act does not appear to have improved gender‐balanced enrollment or promoted the use of gender‐specific analyses in clinical trials published in an influential medical journal. Overcoming this trend will require rigorous efforts on the part of funding entities, trial investigators, and journals disseminating study results. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01782017/full - - -Record #102 of 151 -ID: CN-02246068 -AU: Gai N -AU: Aoyama K -AU: Faraoni D -AU: Goldenberg NM -AU: Levin DN -AU: Maynes JT -AU: McVey MJ -AU: Munshey F -AU: Siddiqui A -AU: Switzer T -AU: et al. -TI: General medical publications during COVID-19 show increased dissemination despite lower validation -SO: PloS one -YR: 2021 -VL: 16 -NO: 2 -PG: e0246427 -PM: PUBMED 33529266 -XR: EMBASE 2010964067 -PT: Journal article -KY: *Bibliometrics; *COVID‐19; *Periodicals as Topic [standards]; *coronavirus disease 2019; *information dissemination; *medical research; *publication; *validation process; Article; Article characteristic; Bibliometrics; Communication; Comparative study; Cross‐Sectional Studies; Cross‐sectional study; Human; Humans; Impact metric; Industry and industrial phenomena; Medical literature; Observational method; Pandemics; Peer Review, Research; Principal Component Analysis; Principal component analysis; Publication characteristic -DOI: 10.1371/journal.pone.0246427 -AB: Background The COVID‐19 pandemic has yielded an unprecedented quantity of new publications, contributing to an overwhelming quantity of information and leading to the rapid dissemination of less stringently validated information. Yet, a formal analysis of how the medical literature has changed during the pandemic is lacking. In this analysis, we aimed to quantify how scientific publications changed at the outset of the COVID‐19 pandemic. Methods We performed a cross‐sectional bibliometric study of published studies in four high‐impact medical journals to identify differences in the characteristics of COVID‐19 related publications compared to non‐pandemic studies. Original investigations related to SARS‐CoV‐2 and COVID‐19 published in March and April 2020 were identified and compared to non‐COVID‐19 research publications over the same two‐month period in 2019 and 2020. Extracted data included publication characteristics, study characteristics, author characteristics, and impact metrics. Our primary measure was principal component analysis (PCA) of publication characteristics and impact metrics across groups. Results We identified 402 publications that met inclusion criteria: 76 were related to COVID‐19; 154 and 172 were non‐COVID publications over the same period in 2020 and 2019, respectively. PCA utilizing the collected bibliometric data revealed segregation of the COVID‐19 literature subset from both groups of non‐COVID literature (2019 and 2020). COVID‐19 publications were more likely to describe prospective observational (31.6%) or case series (41.8%) studies without industry funding as compared with non‐COVID articles, which were represented primarily by randomized controlled trials (32.5% and 36.6% in the non‐COVID literature from 2020 and 2019, respectively). Conclusions In this cross‐sectional study of publications in four general medical journals, COVID‐related articles were significantly different from non‐COVID articles based on article characteristics and impact metrics. COVID‐related studies were generally shorter articles reporting observational studies with less literature cited and fewer study sites, suggestive of more limited scientific support. They nevertheless had much higher dissemination. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02246068/full - - -Record #103 of 151 -ID: CN-01779148 -AU: Lanzafame RJ -TI: Pure or tarnished: are systematic reviews blind or biased? -SO: Photomedicine and laser surgery -YR: 2005 -VL: 23 -NO: 5 -PG: 451‐452 -PM: PUBMED 16262572 -XR: EMBASE 41627896 -PT: Journal article -KY: *laser surgery; Bias; Bibliometrics; Clinical research; Clinical trial; Cochrane Library; Controlled clinical trial; Editorial; Humans; Low‐Level Light Therapy; Medical literature; Osteoarthritis [epidemiology, *radiotherapy]; Publication; Quality control; Randomized Controlled Trials as Topic; Randomized controlled trial; Review Literature as Topic; Sensitivity and Specificity; Systematic review -DOI: 10.1089/pho.2005.23.451 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01779148/full - - -Record #104 of 151 -ID: CN-01725306 -AU: Margaliot Z -AU: Chung KC -TI: Systematic reviews: a primer for plastic surgery research -SO: Plastic and reconstructive surgery -YR: 2007 -VL: 120 -NO: 7 -PG: 1834‐1841 -PM: PUBMED 18090745 -XR: EMBASE 350306678 -PT: Journal article -KY: *medical research; *plastic surgery; Bias; Bibliometrics; Citation analysis; Cochrane Library; Data Collection [methods]; Data analysis; Data base; Data extraction; Data synthesis; Databases, Bibliographic; Embase; Evidence based medicine; Evidence‐Based Medicine; Guidelines as Topic; Human; Information retrieval; MEDLINE; Medline; Meta‐Analysis as Topic; Practice guideline; Priority journal; Publishing; Quality Control; Quality control; Randomized controlled trial; Reproducibility; Research; Review; Review Literature as Topic; Statistical analysis; Surgery, Plastic; Systematic error; Systematic review; Validity; Writing -DOI: 10.1097/01.prs.0000295984.24890.2f -AB: Clinicians rely on review articles to keep current with the rapid accumulation of medical and surgical literature. Traditional expert reviews, however, often suffer from inherent personal biases and may not reflect a true synthesis of the existing literature on a particular subject. Systematic reviews are structured, scientific articles that address the shortcomings of traditional reviews by adhering to strict, reproducible methods and recommended guidelines. The methods are designed to eliminate possible sources of bias, ensure as complete a review of the existing literature as possible, and present the results in a way that is useful for its intended audience. Systematic reviews may at times include a quantitative synthesis of the available data in the form of a meta‐analysis. Meta‐analysis is a statistical tool for combining the numerical results of separate studies to obtain a summary outcome with increased precision due to the larger, combined number of patients. Meta‐analyses may be particularly helpful when individual study results are conflicting and the existing literature is inconclusive. The validity of meta‐analysis, however, is highly dependent on the quality of data available in the literature. In its strictest form, meta‐analysis is used to combine data from only randomized controlled clinical trials. Because randomized controlled clinical trials are infrequently performed in plastic surgery research, this article will focus on systematic reviews to provide the readers with a useful guide in performing this field of study. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01725306/full - - -Record #105 of 151 -ID: CN-01752698 -AU: Bernal-Delgado E -AU: Fisher ES -TI: Abstracts in high profile journals often fail to report harm -SO: BMC medical research methodology -YR: 2008 -VL: 8 -PG: 14 -PM: PUBMED 18371200 -XR: EMBASE 351581167 -PT: Journal article -KY: *medical literature; Abstracting and Indexing; Article; Bibliometrics; Comparative study; Confidence Intervals; Confidence interval; Corrected prevalence ratio; Drug industry; Humans; Iatrogenic Disease; Information Storage and Retrieval [methods]; Logistic Models; Logistic regression analysis; Periodicals as Topic [*standards]; Prevalence; Randomized Controlled Trials as Topic [*standards]; Randomized controlled trial; Statistical significance; Structured interview -DOI: 10.1186/1471-2288-8-14 -AB: BACKGROUND: To describe how frequently harm is reported in the abstract of high impact factor medical journals. DESIGN AND POPULATION: We carried out a blinded structured review of a random sample of 363 Randomised Controlled Trials (RCTs) carried out on human beings, and published in high impact factor medical journals in 2003. Main endpoint: 1) Proportion of articles reporting harm in the abstract; and 2) Proportion of articles that reported harm in the abstract when harm was reported in the main body of the article. ANALYSIS: Corrected Prevalence Ratio (cPR) and its exact confidence interval were calculated. Non‐conditional logistic regression was used. RESULTS: 363 articles and 407 possible comparisons were studied. Overall, harm was reported in 135 abstracts [37.2% (CI95%:32.2 to 42.4)]. Harm was reported in the main text of 243 articles [66.9% (CI95%: 61.8 to 71.8)] and was statistically significant in 54 articles [14.9% (CI95%: 11.4 to 19.0)]. Among the 243 articles that mentioned harm in the text, 130 articles [53.5% (CI95% 47.0 to 59.9)] reported harm in the abstract; a figure that rose to 75.9% (CI95%: 62.4 to 86.5) when the harm reported in the text was statistically significant. Harm in the abstract was more likely to be reported when statistically significant harm was reported in the main body of the article [cPR = 1.70 (CI95% 1.47 to 1.92)] and when drug companies (not public institutions) funded the RCTs [cPR = 1.29 (CI95% 1.03 to 1.67)]. CONCLUSION: Abstracts published in high impact factor medical journals underreport harm, even when harm is reported in the main body of the article. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01752698/full - - -Record #106 of 151 -ID: CN-01762335 -AU: Mathieu S -AU: Boutron I -AU: Moher D -AU: Altman DG -AU: Ravaud P -TI: Comparison of registered and published primary outcomes in randomized controlled trials -SO: JAMA -YR: 2009 -VL: 302 -NO: 9 -PG: 977‐984 -PM: PUBMED 19724045 -XR: EMBASE 355210578 -PT: Journal article -KY: *outcome assessment; *publishing; *randomized controlled trial; Article; Bibliometrics; Cardiology; Comparative study; Gastroenterology; Medical information; Medical literature; Periodicals as Topic [standards, *statistics & numerical data]; Priority journal; Publication Bias; Publishing [standards, statistics & numerical data]; Randomized Controlled Trials as Topic [standards, *statistics & numerical data]; Register; Registries [standards]; Rheumatology; Treatment Outcome -DOI: 10.1001/jama.2009.1242 -AB: CONTEXT: As of 2005, the International Committee of Medical Journal Editors required investigators to register their trials prior to participant enrollment as a precondition for publishing the trial's findings in member journals. OBJECTIVE: To assess the proportion of registered trials with results recently published in journals with high impact factors; to compare the primary outcomes specified in trial registries with those reported in the published articles; and to determine whether primary outcome reporting bias favored significant outcomes. DATA SOURCES AND STUDY SELECTION: MEDLINE via PubMed was searched for reports of randomized controlled trials (RCTs) in 3 medical areas (cardiology, rheumatology, and gastroenterology) indexed in 2008 in the 10 general medical journals and specialty journals with the highest impact factors. DATA EXTRACTION: For each included article, we obtained the trial registration information using a standardized data extraction form. RESULTS: Of the 323 included trials, 147 (45.5%) were adequately registered (ie, registered before the end of the trial, with the primary outcome clearly specified). Trial registration was lacking for 89 published reports (27.6%), 45 trials (13.9%) were registered after the completion of the study, 39 (12%) were registered with no or an unclear description of the primary outcome, and 3 (0.9%) were registered after the completion of the study and had an unclear description of the primary outcome. Among articles with trials adequately registered, 31% (46 of 147) showed some evidence of discrepancies between the outcomes registered and the outcomes published. The influence of these discrepancies could be assessed in only half of them and in these statistically significant results were favored in 82.6% (19 of 23). CONCLUSION: Comparison of the primary outcomes of RCTs registered with their subsequent publication indicated that selective outcome reporting is prevalent. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01762335/full - - -Record #107 of 151 -ID: CN-01737288 -AU: Reeves MD -TI: Increase in quality, but not quantity, of clinical trials in acute pain: 1992 versus 2007 -SO: Anesthesia and analgesia -YR: 2009 -VL: 109 -NO: 5 -PG: 1656‐1658 -PM: PUBMED 19843804 -XR: EMBASE 358123288 -PT: Journal article -KY: *postoperative pain /drug therapy /complication /drug therapy; Acute Disease; Adult; Analgesia; Analgesia [*trends]; Anesthesiology; Article; Bibliometrics; Clinical Trials as Topic [standards]; Clinical trial; Controlled clinical trial; Controlled study; Epidural anesthesia; Human; Humans; Medical literature; Methodology; Pain assessment; Pain, Postoperative [*therapy]; Patient controlled analgesia; Periodicals as Topic [standards]; Postoperative analgesia; Priority journal; Quality Control; Quality of life; Randomized controlled trial; Research Design [standards]; Time Factors; Treatment Outcome; Unspecified side effect /side effect; Visual analog scale -DOI: 10.1213/ANE.0b013e3181b626b6 -AB: The annual number of published clinical trials in acute postoperative pain in adults has changed little in 15 yr and, as a fraction of all clinical trials published in the six highest impact journals in anesthesiology, has actually decreased from 16% (95% confidence interval: 12‐20) to 11% (95% confidence interval: 9‐15). However, the methodological quality of reports has improved, with explicit statements on power analysis, allocation concealment, and specification of primary end points exceeding 90% of reports in 2007. There has been a shift in hypothesis interests away from neuraxial analgesia and toward multimodal analgesia. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01737288/full - - -Record #108 of 151 -ID: CN-01763415 -AU: Klassen TP -AU: Pham B -AU: Lawson ML -AU: Moher D -TI: For randomized controlled trials, the quality of reports of complementary and alternative medicine was as good as reports of conventional medicine -SO: Journal of clinical epidemiology -YR: 2005 -VL: 58 -NO: 8 -PG: 763‐768 -PM: PUBMED 16018911 -XR: EMBASE 40966833 -PT: Journal article -KY: *alternative medicine; *medicine; Analytic method; Bibliometrics; Clinical trial; Comparative study; Complementary Therapies [*standards]; Controlled clinical trial; Data analysis; Humans; Information processing; Language; Periodicals as Topic [*standards]; Priority journal; Publication; Publications [standards]; Qualitative analysis; Quality Assurance, Health Care; Randomized Controlled Trials as Topic [*standards]; Randomized controlled trial; Research Design; Review; Review Literature as Topic; Scoring system; Standardization -DOI: 10.1016/j.jclinepi.2004.08.020 -AB: OBJECTIVE: To compare the quality of reporting of reports randomized controlled trials (RCTs) published in English and in languages other than English (LOE), and to determine whether there were differences between conventional medicine (CM) and complementary and alternative medicine (CAM) reports. STUDY DESIGN AND SETTING: We examined more than 600 RCTs associated with 125 systematic reviews. We extracted characteristics of each RCT using a standardized data collection form. We assessed quality using the Jadad scale and the adequacy of allocation concealment. RESULTS: There were only minor differences in the quality of reports of RCTs published in English compared with other languages (median quality score of 3 vs. 2, P=.10), and the quality of reports of CAM RCTs was similar to the CM reports (median score of 3 vs. 2, P=.14). There was no effect of language of publication on quality of reporting for CM trials (median score of 2 vs. 2, P=.12). Among CAM trials, however, overall quality scores were higher for reports in English than for reports in other languages (median score of 3 vs. 2, P=.04). CONCLUSION: The overall quality of reports published in languages other than English is similar to that of English‐language reports. Moreover, the overall quality of reporting of RCTs of CAM interventions is as good as that for CM interventions. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01763415/full - - -Record #109 of 151 -ID: CN-01762920 -AU: Varnell SP -AU: Murray DM -AU: Janega JB -AU: Blitstein JL -TI: Design and Analysis of Group-Randomized Trials: a Review of Recent Practices -SO: American journal of public health -YR: 2004 -VL: 94 -NO: 3 -PG: 393‐399 -PM: PUBMED 14998802 -XR: EMBASE 38269491 -PT: Journal article -KY: *Bibliometrics; *Cluster Analysis; *Public Health Practice; *group randomized trial; *peer review; *randomization; Analytic method; Calculation; Clinical trial; Controlled clinical trial; Controlled study; Data analysis; Epidemiologic Research Design; Evidence based medicine; Human; Humans; Medical literature; Meta analysis; Methodology; Periodicals as Topic [*statistics & numerical data]; Preventive medicine; Publication; Quality Control; Randomized Controlled Trials as Topic [*methods]; Randomized controlled trial; Review; Sample Size; Sample size; Sensitivity and Specificity; Statistical analysis -DOI: 10.2105/ajph.94.3.393 -AB: We reviewed group‐randomized trials (GRTs) published in the American Journal of Public Health and Preventive Medicine from 1998 through 2002 and estimated the proportion of GRTs that employ appropriate methods for design and analysis. Of 60 articles, 9 (15.0%) reported evidence of using appropriate methods for sample size estimation. Of 59 articles in the analytic review, 27 (45.8%) reported at least 1 inappropriate analysis and 12 (20.3%) reported only inappropriate analyses. Nineteen (32.2%) reported analyses at an individual or subgroup level, ignoring group, or included group as a fixed effect. Hence increased vigilance is needed to ensure that appropriate methods for GRTs are employed and that results based on inappropriate methods are not published. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01762920/full - - -Record #110 of 151 -ID: CN-01288227 -AU: Ramanan M -AU: Myburgh J -AU: Finfer S -AU: Bellomo R -AU: Venkatesh B -TI: Publication of secondary analyses from randomized trials in critical care -SO: New England journal of medicine -YR: 2016 -VL: 375 -NO: 21 -PG: 2105‐2106 -PM: PUBMED 27959732 -XR: EMBASE 613371380 -PT: Journal article -KY: *Critical Care; *Randomized Controlled Trials as Topic; *controlled study; *intensive care; *publication; *randomized controlled trial (topic); *secondary analysis; Bibliometrics; Controlled clinical trial; Datasets as Topic; Human; Humans; Journal impact factor; Letter; Medical literature; Periodicals as Topic [*statistics & numerical data]; Priority journal; Publishing; Publishing [statistics & numerical data]; Randomized controlled trial -DOI: 10.1056/NEJMc1610367 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01288227/full - - -Record #111 of 151 -ID: CN-01734717 -AU: Ezzo J -AU: Bausell B -AU: Moerman DE -AU: Berman B -AU: Hadhazy V -TI: Reviewing the reviews. How strong is the evidence? How clear are the conclusions? -SO: International journal of technology assessment in health care -YR: 2001 -VL: 17 -NO: 4 -PG: 457‐466 -PM: PUBMED 11758290 -XR: EMBASE 33108640 -PT: Journal article -KY: *Evidence‐Based Medicine; *Meta‐Analysis as Topic; *evidence based medicine; Article; Bibliometrics; Clinical research; Clinical trial; Controlled clinical trial; Controlled study; Health care policy; Human; Humans; Medical practice; Meta analysis; Observer Variation; Outcome Assessment, Health Care; Outcomes research; Randomized Controlled Trials as Topic [*statistics & numerical data]; Randomized controlled trial; Rating scale; United States -AB: OBJECTIVES: The objectives of this paper were: a) to determine what can be learned from conclusions of systematic reviews about the evidence base of medicine; and b) to determine whether two readers draw similar conclusions from the same review, and whether these match the authors' conclusions. METHODS: Three methodologists (two per review) rated 160 Cochrane systematic reviews (issue 1, 1998) using pre‐established conclusion categories. Disagreements were resolved by discussion to arrive at a consensual score for each review. Reviews' authors were asked to use the same categories to designate the intended conclusion. Interrater agreements were calculated. RESULTS: Interrater agreement between two readers was 0.68 and 0.72, and between readers and authors, 0.32. The largest categories assigned by methodologists were "positive effect" (22.5%), "insufficient evidence" (21.3%), and "evidence of no effect" (20.0%). The largest categories assigned by authors were "insufficient evidence" (32.4%), "possibly positive" (28.6%), and "positive effect" (26.7%). CONCLUSIONS: The number of reviews indicating that the modern biomedical interventions show either no effect or insufficient evidence is surprisingly high. Interrater disagreements suggest a surprising degree of subjective interpretation involved in systematic reviews. Where patterns of disagreement emerged between authors and readers, authors tended to be more optimistic in their conclusions than the readers. Policy implications are discussed. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01734717/full - - -Record #112 of 151 -ID: CN-01734718 -AU: Garcia-Altes A -AU: Jovell E -TI: Economic analysis of treatment of functional dyspepsia. An assessment of the quality of published studies -SO: International journal of technology assessment in health care -YR: 2001 -VL: 17 -NO: 4 -PG: 517‐527 -PM: PUBMED 11758296 -XR: EMBASE 33108646 -PT: Journal article -KY: *Health Care Costs; *dyspepsia /disease management; *health care cost; Article; Bibliometrics; Clinical trial; Controlled clinical trial; Controlled study; Cost benefit analysis; Cost effectiveness analysis; Databases, Bibliographic; Dyspepsia [*economics, *therapy]; Evidence‐Based Medicine [*economics]; Gastrointestinal disease /disease management; Health Policy; Health economics; Human; Humans; Major clinical study; Multicenter study; Outcomes research; Publishing [standards]; Quality Control; Randomized controlled trial; Spain; Treatment Outcome; Treatment outcome -AB: Objectives: The objective of this study was to assess the quality of economic analysis studies published in the medical and economical literature assessing the clinical management of functional dyspepsia. Methods: Bibliographic search in the main biomedical databases, in articles from bibliographic references, health technology assessment reports, and in gray literature. A specific protocol with economic and clinical items was designed for the evaluation. Results: Overall, 18 of 162 studies met the inclusion criteria for the assessment. The compared treatment options were very diverse. The main methodologic deficiencies were in perspective of analysis, inclusion of indirect costs, and sources of clinical information. Conclusions: Specific checklists with clinical and economical items may help to better assess the quality of economic analysis in the field of functional dyspepsia. The methodologic rigor in the application of economic analysis techniques, as well as the use of appropriate clinical outcome measures, is essential to guarantee the reproducibility of the studies. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01734718/full - - -Record #113 of 151 -ID: CN-01784172 -AU: Sinha S -AU: Sinha S -AU: Ashby E -AU: Jayaram R -AU: Grocott MP -TI: Quality of Reporting in Randomized Trials Published in High-Quality Surgical Journals -SO: Journal of the American College of Surgeons -YR: 2009 -VL: 209 -NO: 5 -PG: 565‐571.e1 -PM: PUBMED 19854395 -XR: EMBASE 50636845 -PT: Journal article -KY: *randomized controlled trial; *surgery; Article; Bibliometrics; Clinical research; General Surgery; Human; Humans; Jadad Score; Journal Impact Factor; Journalism, Medical [*standards]; MEDLINE; Medical Records [*standards]; Medical research; Outcomes research; Periodicals as Topic [standards]; Priority journal; Publication; Quality control; Randomization; Randomized Controlled Trials as Topic; Rating scale; Research Design [standards]; Scoring system -DOI: 10.1016/j.jamcollsurg.2009.07.019 -AB: BACKGROUND: Randomized controlled trials (RCTs) in surgery can provide valuable evidence of the efficacy of interventions if they are well‐designed, appropriately executed, and adequately reported. Adequate reporting of methodology in surgical RCTs is known to be poor, and adverse‐event reporting in surgical research is inconsistent. The Consolidated Standards of Reporting Trials (CONSORT) statement is a framework to help authors report their findings in a transparent manner. Extensions to the CONSORT statement have been published recently to address deficiencies in adverse‐event reporting and in reporting of specific criteria related to nonpharmacologic treatments. The aim of this study was to assess the quality of reporting of trial methodology and adverse events in a sample of general surgical RCTs published in high‐quality surgical journals using the criteria specified in the CONSORT statements. STUDY DESIGN: We used impact factor to identify the top three ranked surgical journals in 2004. We then obtained information on all RCTs published in these journals in the 2005 calendar year. We assessed quality of reporting using Jadad score, compared the quality of RCTs from CONSORT‐endorsing journals with nonendorsers, and assessed the number of RCTs adequately reporting key generic methodologic, adverse‐event‐related, and specific nonpharmacologic criteria. RESULTS: Of 42 RCTs analyzed, only 40% (17 of 42) had a Jadad score > or = 3. There was no significant difference in the number of high‐quality RCTs published in CONSORT‐endorsing journals compared with nonendorsers (p = 0.3). The median percentage of RCTs adequately reporting generic methodologic, adverse‐event‐related, and specific nonpharmacologic criteria was 32.5%, 17%, and 36.5%, respectively. CONCLUSIONS: Quality of reporting of generic methodologic, adverse‐event‐related, and specific nonpharmacologic criteria in surgical RCTs is poor. Increased attention to quality of reporting of surgical RCTs is required if studies are to meet published criteria. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01784172/full - - -Record #114 of 151 -ID: CN-01341681 -AU: Hawkins CM -AU: Hunter M -AU: Kolenic GE -AU: Carlos RC -TI: Social Media and Peer-Reviewed Medical Journal Readership: a Randomized Prospective Controlled Trial -SO: Journal of the American College of Radiology : JACR -YR: 2017 -VL: 14 -NO: 5 -PG: 596‐602 -PM: PUBMED 28268163 -XR: EMBASE 614661115 -PT: Journal article -KY: *medical literature; *peer review; *social media; Bibliometrics; Confidence interval; Control group; Controlled clinical trial; Controlled study; Human; Humans; Journal Impact Factor; Netherlands; Peer Review; Periodicals as Topic [*statistics & numerical data]; Prospective Studies; Radiology; Radiology [*statistics & numerical data]; Random Allocation; Randomized controlled trial; Social Media [*statistics & numerical data]; Student -DOI: 10.1016/j.jacr.2016.12.024 -AB: Objective To prospectively evaluate the impact of increasing levels of social media engagement on page visits and web‐link clicks for content published in the Journal of the American College of Radiology. Methods A three‐arm prospective trial was designed using a control group, a basic Twitter intervention group (using only the Journal's @JACRJournal Twitter account), and an enhanced Twitter intervention group (using the personal Twitter accounts of editorial board members and trainees). Overall, 428 articles published between June 2013 and July 2015 were randomly assigned to the three groups. Article‐specific tweets for both intervention arms were sent between September 14, 2015, and October 28, 2015. Primary end points included article‐specific weekly and monthly page visits on the journal's Elsevier website (Amsterdam, Netherlands). For the two intervention groups, additional end points included 7‐day and 30‐day Twitter link clicks. Results Weekly page visits for the enhanced Twitter arm (mean 18.2; 95% confidence interval [CI] 15.6‐20.7) were significantly higher when compared with the weekly page visits for the control arm (mean 7.6; 95% CI 1.7‐13.6). However, there was no demonstrable increase in weekly page visits (mean 9.4; 95% CI 7.4‐11.5) for the basic Twitter arm compared with the control arm. No intervention effects over control, regardless of Twitter arm assignment, were demonstrated for monthly page visits. The enhanced Twitter intervention resulted in a statistically significant increase in both 7‐day and 30‐day Twitter link clicks compared with the basic Twitter intervention group. Conclusions An organized social media strategy, with focused social media activity from editorial board members, increased engagement with content published in a peer‐reviewed radiology journal. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01341681/full - - -Record #115 of 151 -ID: CN-01760250 -AU: Maeda K -AU: Rahman M -AU: Fukui T -TI: Japan's contribution to clinical research in gastroenterology and hepatology -SO: Journal of gastroenterology -YR: 2003 -VL: 38 -NO: 8 -PG: 816‐819 -PM: PUBMED 14505143 -XR: EMBASE 37161353 -PT: Journal article -KY: *clinical research; *gastroenterology; *liver; Article; Bibliometrics; Biomedical Research [*statistics & numerical data]; Clinical trial; Controlled clinical trial; Controlled study; Gastroenterology [*statistics & numerical data]; Humans; Japan; Medical literature; Medline; Periodicals as Topic [statistics & numerical data]; Priority journal; Randomized Controlled Trials as Topic [statistics & numerical data]; Randomized controlled trial; Statistical analysis; United Kingdom; United States -DOI: 10.1007/s00535-003-1153-4 -AB: Background. Although Japan's contributions to several biomedical fields have already been reported, little is known about Japan's contribution to gastroenterology and hepatology. Methods. Original articles published in 1991 through 2000 in highly reputed journals in the field of gastroenterology and hepatology were retrieved from the MEDLINE database. The number of articles having an affiliation with a Japanese institution was counted in total, and the number for each journal was also counted. Japan's share of articles regarding clinical trials and randomized controlled trials (RCTs) in this field was also determined, along with the trend over the past decade. Results. Japan's share of articles in this field was 10.6%, ranking third in the world, following the United States (35.1%) and the United Kingdom (11.5%). Japan's share of articles went up significantly as a whole (P = 0.01), while the share for RCTs showed no significant change (P = 0.57) during this period of time. Conclusions. Japan's contribution to the field of gastroenterology and hepatology is, in general, acceptable compared with that of other counties, but the contribution for RCTs not satisfactory. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01760250/full - - -Record #116 of 151 -ID: CN-01996444 -AU: Duffett M -AU: Brouwers M -AU: Meade MO -AU: Xu GM -AU: Cook DJ -TI: Research Collaboration in Pediatric Critical Care Randomized Controlled Trials: a Social Network Analysis of Coauthorship -SO: Pediatric critical care medicine -YR: 2020 -VL: 21 -NO: 1 -PG: 12‐20 -PM: PUBMED 31577694 -XR: EMBASE 629513416 -PT: Journal article -KY: *intensive care; *social network; Article; Authorship; Bibliometrics; Biomedical Research [*methods]; Canada; Child; Controlled study; Critical Care; Female; Human; Human experiment; Humans; Intimacy; Male; Multicenter study; Pediatrics; Productivity; Publishing; Randomized Controlled Trials as Topic; Randomized controlled trial; Research Personnel; Social Networking; United Kingdom; United States -DOI: 10.1097/PCC.0000000000002120 -AB: OBJECTIVES: Clinical research is a collaborative enterprise; researchers benefit from the expertise, experience, and resources of their collaborators. We sought to describe the extent and patterns of collaboration among pediatric critical care trialists, and to identify the most influential individuals, centers, and countries. DESIGN: Social network analysis of coauthorship. DATA SOURCES: Publications of pediatric critical care randomized controlled trials (1986‐2018). DATA EXTRACTION: We manually extracted the names of all authors and their affiliations. We used productivity (number of randomized controlled trials), influence (number of citations), and four measures of prominence in the social network (degree, betweenness, closeness, and eigenvector centrality) to identify the most influential individuals. MEASUREMENTS AND MAIN RESULTS: From 415 randomized controlled trials in pediatric critical care, we identified 2,176 trialists from 377 centers in 43 countries. The coauthorship network is highly disconnected and dominated by a single large cluster of trialists publishing 142 (34%) of the randomized controlled trials. However, 119 (29%) of the randomized controlled trials were published by 28 smaller clusters‐a median (interquartile range) of 3 (2‐4) randomized controlled trials each. The remaining 154 (37%) randomized controlled trials were coauthored by researchers publishing a single randomized controlled trial each. This overall structure has remained constant with the publication of new randomized controlled trials over 33 years. The most influential trialists and centers varied according to the metric we used; only one trialist and three centers ranked in the top 10 for all measures of influence. Thirty‐five of the 40 trialists (88%) ranking in the top 10 of any of the measures were from the United States, the United Kingdom, and Canada. CONCLUSIONS: Pediatric critical care has made considerable progress in the number of trialists and randomized controlled trials, but the research enterprise remains highly clustered and fragmented, particularly geographically. Efforts to further increase the quantity and quality of research in the field should include steps to increase the level and range of collaboration. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01996444/full - - -Record #117 of 151 -ID: CN-01754592 -AU: Bailey CS -AU: Fisher CG -AU: Dvorak MF -TI: Type II error in the spine surgical literature -SO: Spine -YR: 2004 -VL: 29 -NO: 10 -PG: 1146‐1149 -PM: PUBMED 15131445 -XR: EMBASE 38649833 -PT: Journal article -KY: *analytical error; *spine surgery; Bibliometrics; Calculation; Clinical trial; Comparative study; Controlled clinical trial; False Negative Reactions; Human; Humans; Hypothesis; Orthopedics; Peer review; Priority journal; Publishing [standards]; Randomized Controlled Trials as Topic [*statistics & numerical data]; Randomized controlled trial; Research Design; Review; Sample Size; Sample size; Spine [*surgery]; Statistical analysis; Treatment Outcome; Treatment outcome -DOI: 10.1097/00007632-200405150-00018 -AB: Study Design. A literature review. Objectives. To determine the frequency of potential type II errors published in the spine surgical literature. Summary of Background Data. The randomized controlled trial is the strongest clinical evidence available in investigational medicine. Unfortunately, it is common for randomized controlled trials published in peer‐reviewed journals not to report a primary question or a sample size calculation. When the null hypothesis is accepted and the power of a study is unreported, the validity of a study's findings may be significantly limited. To our knowledge, the spine literature has not been appraised to determine the frequency of type II errors. Methods. A literature search was conducted of MED‐LINE, PubMed, and Cochrane databases, using the key words of "spine" and "surgery" between 1967 and 2002. Trials were included if they were of a 2‐group randomized controlled trial design, which reported a nonsignificant difference in the primary outcome. The frequency of reporting the primary outcome and sample size calculation was determined. The sample size was assessed to determine whether the trial had sufficient patients to detect a 10%, 25%, and 35% relative difference in the primary outcome for a power of 80%. Results. A total of 37 studies satisfied the inclusion criteria. Six studies reported a sample size calculation (17%). Of the remaining 31 studies, 5 explicitly stated a primary outcome (14%). The mean type II error (beta error) was 82%. Conclusion. The spine surgical literature is plagued with a high potential for type II error. A trial's methodology should be scrutinized to prevent misinterpretation of the results. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01754592/full - - -Record #118 of 151 -ID: CN-01734296 -AU: Wells M -AU: Sarna L -AU: Bialous SA -TI: Nursing research in smoking cessation: a listing of the literature, 1996-2005 -SO: Nursing research -YR: 2006 -VL: 55 -NO: 4 Suppl -PG: S16‐28 -PM: PUBMED 16829773 -XR: EMBASE 44217658 -PT: Journal article -KY: *bibliographic database; *nursing research; *publication; *smoking /prevention; *smoking cessation; *tobacco dependence; Article; Bibliometrics; Classification; Clinical trial; Controlled clinical trial; Databases, Bibliographic [*statistics & numerical data]; Evidence based medicine; Evidence‐Based Medicine; Human; Humans; Nurse attitude; Nurse's Role; Nursing; Nursing Informatics [organization & administration]; Nursing Research [organization & administration, *statistics & numerical data]; Nursing informatics; Organization and management; Periodicals as Topic [*classification]; Practice Guidelines as Topic; Practice guideline; Randomized Controlled Trials as Topic; Randomized controlled trial; Smoking Prevention; Statistics; Tobacco Use Cessation; Tobacco Use Disorder [*nursing]; United States -DOI: 10.1097/00006199-200607001-00004 -AB: A listing of publications related to nurses and tobacco is posted on the Tobacco Free Nurses Web site (www.tobaccofreenurses.org). For this conference, a chronological listing of the numbers and type of data‐based articles that focused on nursing involvement in tobacco cessation published since 1996, the year of the first publication of the Agency for Health Care Policy and Research, Clinical Practice Guideline #18, through 2005 was developed. One hundred and seventy‐five data‐based papers that met the criteria, that is, the paper focused on smoking cessation and involved nurses, were identified. Most (88%) articles were exclusively focused on cessation. Research designs included experimental (38%), quasi‐experimental (24%), descriptive‐quantitative (25%), descriptive‐qualitative (8%), meta‐analyses (2%), and secondary analyses and systematic reviews (each 1%). The number of articles that focused on nursing involvement in tobacco cessation has increased eight fold in the past 10 years, from less than 5 articles published in 1996 to more than 40 published in 2005. The minority (35%) of data‐based articles that focused on nurses and tobacco cessation were published in nursing journals. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01734296/full - - -Record #119 of 151 -ID: CN-01746433 -AU: Castillo D C -AU: Pletikosic C X -AU: Pizarro A F -TI: Randomized controlled clinical studies in Latin American pediatrics -SO: Revista chilena de pediatria -YR: 2009 -VL: 80 -NO: 5 -PG: 420‐426 -XR: EMBASE 358091415 -PT: Journal article -KY: *publication; *randomized controlled trial; Argentina; Article; Bibliometrics; Brazil; Chile; Groups by age; Hospital; Human; Mexico; Neonatology; Nutrition; Observational study; Organization; Parameters; Pediatrics; Psychiatry; Psychology; Respiratory tract disease; South and Central America; Tooth disease; University; Vaccination -AB: Objective: To analyze the production of RCS among children and adolescents in Latin American countries, between 1996 and 2005. Method: In an observational bibliometric study, all available RCS in PUBMED and LILAC data bases for that period were reviewed. Included were studies of children between 0 and 18 years of age, from 19 Latin American countries; 400 references were included. As a control, all pediatric research from the State of New York, USA, for that same period of time was collected. The following parameters were evaluated: number of RCS per country, affiliation, pediatric area, and adjustments were made for population and GNP for each country. Results: Countries with the highest number of publications per year (RCS/yr) were: Brazil (14.6), Mexico (8.6), Chile (5.5), Argentina (3.9). During that same period of time, the State of New York published 26.7 RCS per year. Overall, in Latin America most published specialities were Nutrition (16%), Respiratory Diseases, Dental problems, Vaccinations, Neonatology. In New York, the most frequent specialty reviewed was Psychiatry/Psychology (23.6%). In Chile and Brazil, more than 85% of the studies were performed in Universities, in Mexico and Argentina in Hospitals and other organizations either public or private. Over 90% were published in Journals with ISI impact index. Conclusions: Random studies are rare in Latin America compared to developed countries, mostly conducted in Universities in few countries and focusing on pediatric topics of relevance to them. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01746433/full - - -Record #120 of 151 -ID: CN-01711912 -AU: Eisinga A -AU: Siegfried N -AU: Clarke M -TI: The sensitivity and precision of search terms in Phases I, II and III of the Cochrane Highly Sensitive Search Strategy for identifying reports of randomized trials in medline in a specific area of health care--HIV/AIDS prevention and treatment interventions -SO: Health information and libraries journal -YR: 2007 -VL: 24 -NO: 2 -PG: 103‐109 -PM: PUBMED 17584213 -XR: EMBASE 46946301 -PT: Journal article -KY: *Bibliometrics; *Human immunodeficiency virus infection /prevention /therapy; *Medical Subject Headings; *Medline; *bibliometrics; *randomized controlled trial; Abstracting and Indexing; Article; Clinical Trials, Phase I as Topic [statistics & numerical data]; Clinical Trials, Phase II as Topic [statistics & numerical data]; Clinical Trials, Phase III as Topic [statistics & numerical data]; Documentation; HIV Infections [prevention & control, *therapy]; Human; Humans; MEDLINE [*statistics & numerical data]; Methodology; Phase 1 clinical trial; Phase 2 clinical trial; Phase 3 clinical trial; Priority journal; Randomized Controlled Trials as Topic [*statistics & numerical data]; Reproducibility; Reproducibility of Results; Research Design; Sensitivity and Specificity; Sensitivity and specificity; Statistics; Utilization review -DOI: 10.1111/j.1471-1842.2007.00698.x -AB: OBJECTIVES: To detect term(s) in the Cochrane Highly Sensitive Search Strategy (HSSS) that retain high sensitivity but improve precision in retrieving reports of trials in the PubMed version of medline. METHODS: Individual terms from the PubMed version of the HSSS were added, term by term, to an African HIV/AIDS strategy to identify reports of trials in medline using PubMed. The titles and abstracts of the records retrieved were read by two handsearchers and checked by a clinical epidemiologist. The sensitivity and precision of each term in the three phases of the HSSS were calculated. RESULTS: Of 7,719 records retrieved, 285 were identified as reports of trials [204 randomized (RCTs); 81 possibly randomized or quasi‐randomized (CCTs)]. Phase III had the highest sensitivity (92%). Overall, precision was very low (3.7%). One term, 'random*[tw]', retrieved all RCTs found by our search and improved precision to 29%. The least sensitive terms, yielding no records, were '(doubl* AND mask*)[tw]' and terms containing 'trebl*' or 'tripl*', except for '(tripl* AND blind*)[tw]'. The highest precision per term was for 'Double‐blind Method [MeSH]' (76%). CONCLUSIONS: To retrieve all RCTs and CCTs found by our search, seven terms are needed but precision remains low (4.3%). Developments in the methods of search strategy design may help to improve precision while retaining high levels of sensitivity by identifying term(s) which occur frequently in relevant records and are the most efficient at discriminating between different study designs. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01711912/full - - -Record #121 of 151 -ID: CN-01786692 -AU: Lambers Heerspink HJ -AU: Knol MJ -AU: Tijssen RJ -AU: van Leeuwen TN -AU: Grobbee DE -AU: de Zeeuw D -TI: Is the randomized controlled drug trial in Europe lagging behind the USA? -SO: British journal of clinical pharmacology -YR: 2008 -VL: 66 -NO: 6 -PG: 774‐780 -PM: PUBMED 19032722 -XR: EMBASE 352720332 -PT: Journal article -KY: *drug screening; *randomized controlled trial; Article; Australia; Bibliometrics; Biomedical Research [*economics, organization & administration]; Clinical study; Data base; Drug Industry [*economics, organization & administration]; Drug industry; Europe; Female; Financing, Government [*economics, organization & administration]; Funding; Government; Humans; Japan; Linear Models; Male; Medical research; Medline; Periodicals as Topic [economics]; Pharmaceutical Preparations [*economics]; Population size; Priority journal; Publication; Qualitative analysis; Quantitative analysis; Randomized Controlled Trials as Topic [*economics]; Statistical analysis; United States -DOI: 10.1111/j.1365-2125.2008.03296.x -AB: AIMS: Performance of randomized controlled drug trials (drugRCTs) adds to the scientific output, scientific knowledge, scientific training and up‐to‐date status of healthcare and may drive economy. The purpose of this study was to benchmark Europe's position on drugRCTs relative to the rest of the world, and to identify factors that may drive this performance. METHODS: The number of scientific publications on drugRCTs, indexed in PubMed and Thomson Scientific/Web of Science database over the period 1995‐2004, was used as a proxy measure for the quantitative drugRCT output. The international citation impact of these publications was used as a proxy measure for the qualitative drugRCT output. RESULTS: Country's origin of 103 211 publications was determined. After adjustment for population size, the number of drugRCT publications from Europe, USA and Australia/Japan was 102, 124 and 44 publications per million inhabitants, respectively. The proportional increase in publication output from 1995 until 2004 was lower in Europe compared with the USA and Australia/Japan (29.1, 40.1 and 63.4%, respectively). The number of citations per publication was 4.9 in Europe, 7.0 in the USA and 3.4 in Australia/Japan. Within Europe, the UK, Germany and Italy produced most publications. Country‐specific factors associated with publication output in Europe were the number of pharmaceutical companies with headquarters in a country (R(2) = 0.71, P < 0.001), national R&D expenditures by pharmaceutical companies (R(2) = 0.63, P < 0.001) and health‐related R&D expenditures by national governments (R(2) = 0.22, P = 0.052). CONCLUSIONS: When adjusted for population size, quantitative and qualitative performance of drugRCTs in Europe lags behind the USA but is ahead of Australia/Japan. Several factors appear to explain the differences, among which are the number of headquarters of pharmaceutical companies in a country, the research expenditures by pharmaceutical companies, as well as health‐related R&D expenditures of a country. To enhance and strengthen Europe's position, researchers may strengthen their collaborations with local pharmaceutical companies, and national governments could increase their budgets for medical research funding. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01786692/full - - -Record #122 of 151 -ID: CN-01714834 -AU: McKibbon KA -AU: Wilczynski NL -AU: Haynes RB -TI: Retrieving randomized controlled trials from medline: a comparison of 38 published search filters -SO: Health information and libraries journal -YR: 2009 -VL: 26 -NO: 3 -PG: 187‐202 -PM: PUBMED 19712211 -XR: EMBASE 355177852 -PT: Journal article -KY: *Medline; *information retrieval; *randomized controlled trial; Abstracting and Indexing [*methods]; Article; Bibliographic database; Bibliometrics; Clinical research; Filter; Humans; Information Storage and Retrieval [*methods]; Library; MEDLINE; Medical Subject Headings; Medical research; Priority journal; Randomized Controlled Trials as Topic [*statistics & numerical data]; Reproducibility of Results; Research Design; Sensitivity and Specificity; Subject Headings; Terminology as Topic; United States -DOI: 10.1111/j.1471-1842.2008.00827.x -AB: BACKGROUND: People search medline for trials of healthcare interventions for clinical decisions, or to produce systematic reviews, practice guidelines, or technology assessments. Finding all relevant randomized controlled trials (RCTs) with little extraneous material is challenging. OBJECTIVE: To provide comparative data on the operating characteristics of search filters designed to retrieve RCTs from medline. METHODS: We identified 38 filters. The testing database comprises handsearching data from 161 clinical journals indexed in medline. Sensitivity, specificity and precision were calculated. RESULTS: The number of terms and operating characteristics varied considerably. Comparing the retrieval against the single term 'randomized controlled trials.pt.' (sensitivity for retrieving RCTs, 93.7%), 24 of 38 filters had statistically higher sensitivity; 6 had a sensitivity of at least 99.0%. Four other filters had specificities (non retrieval of non‐RCTs) that were statistically not different or better than the single term (97.6%). Precision was poor: only two filters had precision (proportion of retrieved articles that were RCTs) statistically similar to that of the single term (56.4%)‐all others were lower. Filters with more search terms often had lower specificity, especially at high sensitivities. CONCLUSION: Many RCT filters exist (n = 38). These comparative data can direct the choice of an RCT filter. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01714834/full - - -Record #123 of 151 -ID: CN-01785626 -AU: Gluud LL -AU: Sørensen TI -AU: Gøtzsche PC -AU: Gluud C -TI: The journal impact factor as a predictor of trial quality and outcomes: cohort study of hepatobiliary randomized clinical trials -SO: American journal of gastroenterology -YR: 2005 -VL: 100 -NO: 11 -PG: 2431‐2435 -PM: PUBMED 16279896 -XR: EMBASE 43919673 -PT: Journal article -KY: *hepatobiliary system; Alcohol liver cirrhosis; Article; Autoimmune disease; Bibliometrics; Biliary Tract Diseases; Clinical trial; Cohort Studies; Cohort analysis; Controlled clinical trial; Data Interpretation, Statistical; Gallstone; Hepatic encephalopathy; Hepatitis; Humans; Liver Diseases; Liver cell carcinoma; Liver cirrhosis; Liver failure; Medical literature; Outcome assessment; Patient Selection; Periodicals as Topic [*standards]; Portal hypertension; Primary biliary cirrhosis; Priority journal; Publication; Quality control; Random Allocation; Randomized Controlled Trials as Topic [*standards]; Randomized controlled trial; Research Design [standards]; Sample Size; Statistics, Nonparametric; Treatment Outcome -DOI: 10.1111/j.1572-0241.2005.00327.x -AB: OBJECTIVES: To examine the association between the impact factor and characteristics of hepatobiliary randomized clinical trials. METHODS: A cohort study of 530 hepatobiliary randomized clinical trials was performed. The journal impact factor was extracted from Science Citation Index. For each trial, we extracted the sample size, the quality of randomization and blinding methods, and the statistical significance of the primary outcome measure. RESULTS: The median sample size was 45 participants (interquartile range 25‐88). The allocation sequence generation was adequate in 273 trials (52%). Allocation concealment was adequate in 178 trials (34%). The primary outcome measure was statistically significant in 374 (71%) trials. Nonparametric analyses for trend indicated that the impact factor was significantly associated with the sample size (p < 0.01) and the proportion of trials with adequate allocation sequence generation (p < 0.01) or allocation concealment (p= 0.02). The impact factor was not significantly associated with the study outcome (p= 0.28). CONCLUSIONS: The present study supports the use of the impact factor as a rough quality indicator. However, even trials in high impact journals may be small or may have inadequate quality. Critical appraisal of individual trials is always necessary, irrespective of the place of publication. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01785626/full - - -Record #124 of 151 -ID: CN-01780146 -AU: Snodgrass SR -AU: Parks BR -TI: Anticonvulsant blood levels: historical review with a pediatric focus -SO: Journal of child neurology -YR: 2000 -VL: 15 -NO: 11 -PG: 734‐746 -PM: PUBMED 11108507 -XR: EMBASE 32057417 -PT: Journal article -KY: *benign childhood epilepsy /drug therapy; Adolescent; Anticonvulsants [blood, *history, pharmacokinetics, therapeutic use]; Article; Bibliometrics; Biological Availability; Child; Clinical feature; Clinical trial; Controlled clinical trial; Controlled study; Correlation function; Dose response; Dose‐Response Relationship, Drug; Double blind procedure; Double‐Blind Method; Drug Therapy, Combination; Drug blood level; Electroencephalogram; Epilepsy [blood, drug therapy, *history]; Female; History, 20th Century; Human; Humans; Major clinical study; Male; Patient Compliance; Pharmacodynamics; Priority journal; Randomized Controlled Trials as Topic [history]; Randomized controlled trial; Retrospective Studies; Side effect /side effect; Therapeutic Equivalency -DOI: 10.1177/088307380001501105 -AB: Epilepsy is heterogeneous and its treatment is often complicated by variable drug responses. Buchtal et al reported a close correlation between serum phenytoin levels, electroencephalographic findings, and clinical status in 1960. They suggested that physicians adjust dosage to attain a "therapeutic level." The concept was enthusiastically received. "Therapeutic serum levels" were proposed for most anticonvulsant drugs, and by 1975, most authorities believed that pharmacokinetic factors explained individual differences in drug response. However, Froscher found that measuring levels did not improve patient outcome. More recently, Schumacher's double‐blind study found no correlation between phenytoin levels and seizure control or adverse effects. Pharmacodynamic variables (differences in drug responsiveness) are more important than pharmacokinetic factors for many drugs, especially receptor‐active drugs. Pharmacokinetic variables were studied first, and led to a simplistic model. They are less significant than pharmacodynamic factors in the case of warfarin anticoagulation. Anticonvulsant levels can reveal noncompliance and pharmacokinetic differences. They say nothing about pharmacodynamics. Reports of "subtherapeutic levels" imply a need to increase dosage, but this is not supported by outcome data. We still lack evidence that specific drug levels are a valid intermediate target 40 years after Buchtal's paper. Responses to some anticonvulsants could depend primarily on pharmacokinetic factors, while pharmacodynamic factors could be supreme for others. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01780146/full - - -Record #125 of 151 -ID: CN-01783914 -AU: Papatheodorou SI -AU: Trikalinos TA -AU: Ioannidis JP -TI: Inflated numbers of authors over time have not been just due to increasing research complexity -SO: Journal of clinical epidemiology -YR: 2008 -VL: 61 -NO: 6 -PG: 546‐551 -PM: PUBMED 18471658 -XR: EMBASE 50087712 -PT: Journal article -KY: *author; *medical research; Article; Authorship; Bibliometrics; Biomedical Research [*trends]; Case report; Clinical study; Clinical trial; Europe; Humans; Medical Records [statistics & numerical data]; Medical literature; Meta analysis; North America; Periodicals as Topic [statistics & numerical data, trends]; Priority journal; Publishing [statistics & numerical data, trends]; Random sample; Randomization; Randomized Controlled Trials as Topic [statistics & numerical data, trends]; Randomized controlled trial; Sample size; Statistical significance -DOI: 10.1016/j.jclinepi.2007.07.017 -AB: OBJECTIVE: To examine trends in and determinants of the number of authors in clinical studies. STUDY DESIGN AND SETTING: We analyzed determinants of the number of authors in 633 articles of randomized trials and 313 articles of nonrandomized studies included in large meta‐analyses (seven and six topics, respectively). Analyses were adjusted for topic. We also evaluated 310 randomly sampled case reports that had an abstract and described a single case. RESULTS: After adjusting for topic and other determinants, for both randomized trials and nonrandomized studies, the number of authors increased by 0.8 per decade (P<0.001). Topic was a strong determinant of the number of authors; other independent factors included journal impact factor, multinational authorship, and (for randomized trials) article length and sample size. Trials from South Europe (+1.1 authors) and North America (+0.9) and nonrandomized studies from South Europe (+1.8) had more authors than studies from North Europe (P<0.001). For case reports, only geographic location and article length were significantly related with author numbers. CONCLUSION: The number of authors in articles of randomized and nonrandomized studies has increased over time, even after adjusting for the topic, size, and visibility of a study. The academic coinage of authorship may be suffering from inflation. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01783914/full - - -Record #126 of 151 -ID: CN-01721193 -AU: Gravel J -AU: Opatrny L -AU: Shapiro S -TI: The intention-to-treat approach in randomized controlled trials: are authors saying what they do and doing what they say? -SO: Clinical trials (London, England) -YR: 2007 -VL: 4 -NO: 4 -PG: 350‐356 -PM: PUBMED 17848496 -XR: EMBASE 47572267 -PT: Journal article -KY: *randomized controlled trial; *statistical analysis; Accuracy; Article; Bibliometrics; Cross‐Sectional Studies; Data Interpretation, Statistical; Ethics, Research; Follow up; Humans; Intention; Methodology; Observer Variation; Outcome Assessment, Health Care; Peer Review, Research; Priority journal; Publication Bias; Randomized Controlled Trials as Topic [ethics, *methods]; Reliability; Research Design; Sample Size; Standardization; Treatment Outcome -DOI: 10.1177/1740774507081223 -AB: BACKGROUND: Intention‐to‐treat (ITT) is an approach to the analysis of randomized controlled trials (RCT) in which patients are analyzed as randomized regardless of the treatment actually received. PURPOSE: To ascertain the proportion of RCT reporting the use of intention‐to‐treat and the accuracy of that report and to examine the distribution and analysis of missing data for the studies reporting an ITT analysis. METHOD: We conducted a cross‐sectional literature review of RCTs reported in 10 medical journals in 2002. All articles were assessed using a standardized form. Two evaluators independently reviewed a 10% sample of articles to assess reliability. Subsequently, one evaluator reviewed the remaining articles. The proportion of articles reporting the use of ITT was calculated. Among these, the proportion of articles that ;analyzed patients as randomized' and the proportion and analysis of missing data were evaluated using standardized definitions. RESULTS: Of the 403 articles, 249 (62%) reported the use of ITT. Among these, available patients were clearly analyzed as randomized in 192 (77%). Authors used a modified ITT in 23 (9%); clearly violated a major component of ITT in 17 (7%), and the approach used was unclear in 17 (7%). More than 60% of articles had missing data in their primary analysis. Few articles reported a strategy for missing data. The main reason for missing data was loss to follow‐up. LIMITATIONS: A single evaluator evaluated most articles, but the high concordance obtained during the inter‐rater evaluation suggests that the assessments were consistent. In addition, the small spectrum of journals limits generalizability. Finally, there could be a difference between what was reported and what was performed. CONCLUSIONS: This study emphasizes that authors use the label ;intention‐to‐treat' quite differently. The most common use refers to the analysis of all available subjects as randomized regardless of the missing data aspect. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01721193/full - - -Record #127 of 151 -ID: CN-01721871 -AU: Teoh DC -AU: Schramm B -TI: Changes in clinical research in anaesthesia and intensive care from 1974-2004 -SO: Anaesthesia and intensive care -YR: 2006 -VL: 34 -NO: 6 -PG: 753‐757 -PM: PUBMED 17183893 -XR: EMBASE 46023610 -PT: Journal article -KY: *anesthesia; *clinical research; *intensive care; Anesthesia [*statistics & numerical data, trends]; Animals; Bibliometrics; Biomedical Research [*statistics & numerical data, trends]; Chi square test; Chi‐Square Distribution; Clinical trial; Comparative study; Controlled clinical trial; Controlled study; Critical Care [*statistics & numerical data, trends]; Human; Humans; Intervention study; Longitudinal Studies; Medical education; Methodology; Periodicals as Topic [*statistics & numerical data, trends]; Quality control; Randomized controlled trial; Review; Systematic error; Systematic review; Total quality management -DOI: 10.1177/0310057X0603400614 -AB: The purpose was to identify how the quality of anaesthesia research has improved from articles published in Anaesthesia and Intensive Care over 25 years. Original papers were included during the periods 1974‐1978 and 2000‐2004. Each article was classified according to principal research designs and the two five‐year periods were compared. All interventional trials were evaluated according to the following a priori criteria: author number; ethics approval; informed consent; competing financial interest; eligibility criteria; sample size calculation; method of randomization; patients accounted for, blind assessment of outcome; adverse outcomes; statistical method stated; type I error; type II error; and anaesthetic department of origin. Comparisons of above criteria were made between the two groups using chi‐square test or Fischer's exact test. Two‐hundred‐and‐ninety‐two articles were reviewed in 1974‐1978 and 529 articles were reviewed in 2000‐2004. Animal/ laboratory articles decreased from 17.47% to 12.28% (P=0.05). Review articles decreased from 34.35% to 10.4% (P<0.0001). Descriptive trials increased from 28.4% to 52.72% (P<0.0001). Interventional trials increased from 18.84% to 22.31% (P=0.269). Uncontrolled clinical trials decreased from 27.27% to 12.71%, non‐randomized controlled trials decreased from 50.91% to 7.63%, and randomized controlled trials increased from 21.82% to 79.66% (P<0.0001). All interventional trials criteria improved and were statistically significant except competing financial interest, method of randomization, patients accounted for, and type II error. The quality of anaesthetic research has improved in Anaesthesia and Intensive Care over the past 30 years. However, there is still room for improvement. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01721871/full - - -Record #128 of 151 -ID: CN-01178021 -AU: Gabler NB -AU: Duan N -AU: Raneses E -AU: Suttner L -AU: Ciarametaro M -AU: Cooney E -AU: Dubois RW -AU: Halpern SD -AU: Kravitz RL -TI: No improvement in the reporting of clinical trial subgroup effects in high-impact general medical journals -SO: Trials -YR: 2016 -VL: 17 -NO: 1 -PG: 320 -PM: PUBMED 27423688 -XR: EMBASE 611210044 -PT: Journal article -KY: *funding; *patient decision making; *physician; *sample size; Bibliometrics; Clinical trial; Controlled clinical trial; Controlled study; Data Interpretation, Statistical; Human; Humans; Journal Impact Factor; Logistic Models; Logistic regression analysis; Models, Statistical; Multivariate Analysis; Odds Ratio; Periodicals as Topic [*statistics & numerical data]; Randomized Controlled Trials as Topic [methods, *statistics & numerical data]; Randomized controlled trial; Research Design [*statistics & numerical data]; Statistical model -DOI: 10.1186/s13063-016-1447-5 -AB: Background: When subgroup analyses are not correctly analyzed and reported, incorrect conclusions may be drawn, and inappropriate treatments provided. Despite the increased recognition of the importance of subgroup analysis, little information exists regarding the prevalence, appropriateness, and study characteristics that influence subgroup analysis. The objective of this study is to determine (1) if the use of subgroup analyses and multivariable risk indices has increased, (2) whether statistical methodology has improved over time, and (3) which study characteristics predict subgroup analysis. Methods: We randomly selected randomized controlled trials (RCTs) from five high‐impact general medical journals during three time periods. Data from these articles were abstracted in duplicate using standard forms and a standard protocol. Subgroup analysis was defined as reporting any subgroup effect. Appropriate methods for subgroup analysis included a formal test for heterogeneity or interaction across treatment‐by‐covariate groups. We used logistic regression to determine the variables significantly associated with any subgroup analysis or, among RCTs reporting subgroup analyses, using appropriate methodology. Results: The final sample of 416 articles reported 437 RCTs, of which 270 (62 %) reported subgroup analysis. Among these, 185 (69 %) used appropriate methods to conduct such analyses. Subgroup analysis was reported in 62, 55, and 67 % of the articles from 2007, 2010, and 2013, respectively. The percentage using appropriate methods decreased over the three time points from 77 % in 2007 to 63 % in 2013 (p < 0.05). Significant predictors of reporting subgroup analysis included industry funding (OR 1.94 (95 % CI 1.17, 3.21)), sample size (OR 1.98 per quintile (1.64, 2.40), and a significant primary outcome (OR 0.55 (0.33, 0.92)). The use of appropriate methods to conduct subgroup analysis decreased by year (OR 0.88 (0.76, 1.00)) and was less common with industry funding (OR 0.35 (0.18, 0.70)). Only 33 (18 %) of the RCTs examined subgroup effects using a multivariable risk index. Conclusions: While we found no significant increase in the reporting of subgroup analysis over time, our results show a significant decrease in the reporting of subgroup analyses using appropriate methods during recent years. Industry‐sponsored trials may more commonly report subgroup analyses, but without utilizing appropriate methods. Suboptimal reporting of subgroup effects may impact optimal physician‐patient decision‐making. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01178021/full - - -Record #129 of 151 -ID: CN-01773375 -AU: Royle P -AU: Milne R -TI: Literature searching for randomized controlled trials used in Cochrane reviews: rapid versus exhaustive searches -SO: International journal of technology assessment in health care -YR: 2003 -VL: 19 -NO: 4 -PG: 591‐603 -PM: PUBMED 15095765 -XR: EMBASE 38405633 -PT: Journal article -KY: *Review Literature as Topic; *medical literature; *medical research; Bibliometrics; Clinical trial; Cochrane Library; Comparative study; Controlled clinical trial; Controlled study; Data base; Databases, Bibliographic [statistics & numerical data]; Embase; Human; Information Storage and Retrieval [*methods, statistics & numerical data]; Medline; Meta‐Analysis as Topic; Quality control; Randomized Controlled Trials as Topic [classification, *statistics & numerical data]; Randomized controlled trial; Review; Technology Assessment, Biomedical [methods] -DOI: 10.1017/s0266462303000552 -AB: Objectives: To analyze sources searched in Cochrane reviews, to determine the proportion of trials included in reviews that are indexed in major databases, and to compare the quality of these trials with those from other sources. Methods: All new systematic reviews in the Cochrane Library, Issue1 2001, that were restricted to randomized controlled trials (RCTs) or quasi‐RCTs were selected. The sources searched in the reviews were recorded, and the trials included were checked to see whether they were indexed in four major databases. Trials not indexed were checked to determine how they could be identified. The quality of trials found in major databases was compared with those found from other sources. Results: The range in the number of databases searched per review ranged between one and twenty‐seven. The proportion of the trials in the four databases were Cochrane Controlled Trials Register= 78.5%, MEDLINE = 68.8%, Embase = 65.0%, and Science/Social Sciences Citation Index = 60.7%. Searching another twenty‐six databases after Cochrane Controlled Trials Register (CCTR), MEDLINE, and Embase only found 2.4% additional trials. There was no significant difference between trials found in the CCTR, MEDLINE, and Embase compared with other trials, with respect to adequate allocation concealment or sample size. Conclusions: There was a large variation between reviews in the exhaustiveness of the literature searches. CCTR was the single best source of RCTs. Additional database searching retrieved only a small percentage of extra trials. Contacting authors and manufacturers to find unpublished trials appeared to be a more effective method of obtaining the additional better quality trials. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01773375/full - - -Record #130 of 151 -ID: CN-01297758 -AU: Hajibandeh S -AU: Hajibandeh S -AU: Antoniou SA -AU: Antoniou GA -AU: Torella F -TI: Industry sponsorship and positive outcome in vascular and endovascular randomised trials -SO: VASA. Zeitschrift fur gefasskrankheiten -YR: 2017 -VL: 46 -NO: 1 -PG: 67‐68 -PM: PUBMED 27889961 -XR: EMBASE 614088144 -PT: Journal article -KY: *Research Design; *Research Support as Topic [ethics]; *controlled study; *endovascular surgery; Access to information; Bias; Bibliometrics; Citation analysis; Conflict of Interest; Controlled clinical trial; Endovascular Procedures [*economics, ethics]; Health Care Sector [*economics, ethics]; Human; Humans; Letter; Outcome assessment; Publication; Randomized Controlled Trials as Topic [*economics, ethics]; Randomized controlled trial; Randomized controlled trial (topic); Treatment Outcome; Vascular Surgical Procedures [*economics, ethics] -DOI: 10.1024/0301-1526/a000592 -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01297758/full - - -Record #131 of 151 -ID: CN-01773881 -AU: Barbui C -AU: Cipriani A -AU: Malvini L -AU: Tansella M -TI: Validity of the impact factor of journals as a measure of randomized controlled trial quality -SO: Journal of clinical psychiatry -YR: 2006 -VL: 67 -NO: 1 -PG: 37‐40 -PM: PUBMED 16426086 -XR: EMBASE 43213280 -PT: Journal article -KY: *health care quality; *medical research; Anxiety disorder /drug therapy; Article; Bibliometrics; Clinical trial; Cochrane Library; Controlled clinical trial; Controlled study; Databases, Bibliographic; Depression /drug therapy; Human; Humans; Measurement; Medical literature; Meta analysis; Neurosis /drug therapy; Peer Review, Research; Periodicals as Topic [*statistics & numerical data]; Priority journal; Publication; Publishing [*standards, statistics & numerical data]; Quality control; Randomized Controlled Trials as Topic [*standards, statistics & numerical data]; Randomized controlled trial; Reproducibility of Results; Research Design [*statistics & numerical data]; Systematic review; Validation study -DOI: 10.4088/jcp.v67n0106 -AB: OBJECTIVE: To assess whether the impact factor, a measure of the frequency with which journal articles are cited in the scientific literature, is a proxy measure of the quality of articles reporting the results of randomized controlled trials. METHOD: The quality of trials included in an ongoing Cochrane review concerned with the antidepressant fluoxetine was assessed using the Cochrane Collaboration Depression, Anxiety, and Neurosis quality assessment instrument, the Jadad scale, and the quality criterion of the Cochrane Collaboration Handbook. Journal impact factors were extracted from the Journal Citation Report. RESULTS: A total of 131 articles reported results from 132 clinical trials comparing fluoxetine with other antidepressants. The relationship between trial quality and the impact factor of journals where these studies were published, stratified by period of publication, revealed that journals with impact factors above 4 points published only trials with above‐average overall quality ratings, while journals with impact factors below 4 points published both high‐ and low‐quality trials. The Jadad scale revealed similar quality in trials published in journals with high, medium, and low impact factors (Pearson chi(2) = 0.298, p = .861), and the quality criterion of the Cochrane Collaboration Handbook showed unclear randomization in the majority of trials and in all 15 trials published in high‐impact factor journals (Pearson chi(2) = 4.678, p = .096). CONCLUSION: The impact factor of journals is not a valid measure of randomized controlled trial quality. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01773881/full - - -Record #132 of 151 -ID: CN-02142873 -AU: Pouliliou S -AU: Nikolaidis C -AU: Drosatos G -TI: Current trends in cancer immunotherapy: a literature-mining analysis -SO: Cancer immunology, immunotherapy -YR: 2020 -VL: 69 -NO: 12 -PG: 2425‐2439 -PM: PUBMED 32556496 -XR: EMBASE 2005252947 -PT: Journal article -KY: *Bibliometrics; *cancer immunotherapy; *data mining; Adaptive immunity; Antineoplastic Agents, Immunological [therapeutic use]; Apoptosis; Article; Bone marrow transplantation; Breast cancer; Cancer Vaccines [therapeutic use]; Cancer chemotherapy; Cancer diagnosis; Cancer gene therapy; Cancer immunization; Cancer immunology; Cancer prognosis; Cancer radiotherapy; Cancer research; Cancer stem cell; Cancer survival; Carcinogenesis; Cell adhesion; Cell metabolism; Central nervous system cancer; Chimeric antigen receptor T‐cell immunotherapy; Chronic lymphatic leukemia; Clinical research; Colorectal cancer; Cytotoxic T lymphocyte; Data Mining; Epigenetics; Flow cytometry; Gene expression; Gene mutation; Hematologic malignancy; Human; Humans; Immunohistochemistry; Immunotherapy [methods, *trends]; Lung cancer; Lymph node metastasis; Lymphoma; Melanoma; Mutation; Natural killer T cell; Neoplasms [genetics, immunology, *therapy]; Nonhuman; Papillomavirus Vaccines [therapeutic use]; Papillomavirus infection; Priority journal; Prostate cancer; PubMed [statistics & numerical data]; Radioimmunotherapy; Randomized Controlled Trials as Topic; Regulatory T lymphocyte; Signal transduction; Solid malignant neoplasm; Th1 cell; Th2 cell; Translational research; Tumor microenvironment; Tumor model; Tumor virus -DOI: 10.1007/s00262-020-02630-8 -AB: Cancer immunotherapy is a rapidly growing field that is completely transforming oncology care. Mining this knowledge base for biomedically important information is becoming increasingly challenging, due to the expanding number of scientific publications, and the dynamic evolution of this subject with time. In this study, we have employed a literature‐mining approach that was used to analyze the cancer immunotherapy‐related publications listed in PubMed and quantify emerging trends. A total of 93,033 publications published in 5055 journals have been retrieved, and 141 meaningful topics have been identified, which were further classified into eight distinct categories. Statistical analysis indicates a mean annual increase in the number of published papers of approximately 8% in the last 20 years. The research topics that exhibited the highest trends included "immune checkpoint inhibitors," "tumor microenvironment," "HPV vaccination," "CAR T‐cells," and "gene mutations/tumor profiling." The top identified cancer types included "lung," "colorectal," and "breast cancer," and a shift in popularity from hematological to solid tumors was observed. As regards clinical research, a transition from early phase clinical trials to randomized control trials was recorded, indicating that the field is entering a more advanced phase of development. Overall, this mining approach provided an unbiased analysis of the cancer immunotherapy literature in a time‐conserving and scale‐efficient manner. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02142873/full - - -Record #133 of 151 -ID: CN-01076277 -AU: Kerry R -AU: Arthur A -AU: Mumford S -TI: Scientific truth and physiotherapy trials: an empirical study of truth status in published controlled trial findings -SO: Physiotherapy (united kingdom) -YR: 2011 -VL: 97 -CC: Complementary Medicine -PG: eS603‐eS604 -XR: EMBASE 71882996 -PT: Journal article; Conference proceeding -KY: *controlled study; *empiricism; *evidence based practice; *human; *physiotherapy; Acupuncture; Bibliometrics; Carpal tunnel syndrome; Cerebrovascular accident; Confidence interval; Gold standard; Independent variable; Intention to treat analysis; Logistic regression analysis; Low back pain; Medicine; Model; Prediction; Probability; Randomized controlled trial; Rehabilitation; Risk; Standing; Systematic review (topic) -DOI: 10.1016/j.physio.2011.04.002 -AB: Purpose: To provide insight into the progress of physiotherapy science since the onset of controlled trial methods and the evidence based practice movement. Relevance: After almost 20 years of evidence based practice, we are in a position to examine the scientific progress of physiotherapy. Physiotherapy science assumes a positivist stance; presupposing an external truth. Research methods are used to approximate to this truth, the gold standard being the randomised controlled trial (RCT). As RCTs in physiotherapy improve in quality, physiotherapy science should progress towards a consistent truth. However, investigations into the truth status of RCTs in medical science suggest that a high proportion of trial findings are not consistent with truth (Ioannidis, JAMA 2005;294:218‐28). This project adapts Ioannidis's method to provide an empirical analysis of physiotherapy science by examining the truth status of physiotherapy trials. Participants: 93 published trials (1977‐2010) included in contemporaneous high quality clinical guidelines or systematic reviews concerning: cervical manipulation (n = 22); acupuncture for low back pain (n = 22); stroke rehabilitation (n = 13); interventions for carpal tunnel syndrome (n = 26), and manipulation for low back pain (n = 10). Methods: Independent variables relating to trial quality factors and bibliometrics were recorded and categorised into binary outcomes. Two definitions of 'truth' were used: ultimate‐truth (ULT) was determined using data from the most recent clinical guidelines and systematic reviews. Realtime‐ truth (RTT) was determined using data available at the time of each trial publication. Analysis: Individual trials were categorised as true or false based on their relationship to ULT and RTT. Percentages of true findings were calculated and plotted over time. Binary logistic regression models were computed for both ULT and RTT using all independent variables of trial quality. Bayesian Markov chain Monte Carlo (MCMC) analysis was used to predict probabilities of future trial truth status. Results: Proportions of true findings (ULT, RTT) were; cervical manipulation (50%, 32%), acupuncture for low back pain (68%, 55%), stroke rehabilitation (54%, 62%), interventions for carpal tunnel syndrome (35%, 46%), manipulation for low back pain (40%, 50%). Trends and regression outcomes were similar across topics. Based on combined data there were no temporal trends towards consistent truth. Good fitting regression models for ULT found one significant predictor for truth status (intention‐to‐treat analysis p = 0.05) in favour of false trial prediction. Models for RTT found no significant predictors. All odds ratios had wide confidence intervals. MCMC predictions for ≥60% of future trial chains being true were (ULT, RTT): sceptic prior (0.001%, 0.001%), uniform prior (5%, 2%) and enthusiastic prior (66%, 68%). Conclusions: In line with previous data, a high proportion of trial findings were not consistent with truth. The truth status of physiotherapy trials appears to be independent of time and quality variables. Most Bayesian prediction models reveal a low probability of future trial chains being true. Implications: This work raises questions about the progress and trajectory of physiotherapy science. These findings suggest reliance on trials to approximate to the truth maybe a tenuous stance. Future work should focus on concerns of epistemic risk within physiotherapy science. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01076277/full - - -Record #134 of 151 -ID: CN-01288584 -AU: Pandis N -AU: Fleming PS -AU: Koletsi D -AU: Hopewell S -TI: The citation of relevant systematic reviews and randomised trials in published reports of trial protocols -SO: Trials -YR: 2016 -VL: 17 -NO: 1 -PG: 581 -PM: PUBMED 27927219 -XR: EMBASE 613537855 -PT: Journal article -KY: *controlled study; Bibliometrics; Clinical Protocols; Conflict of interest; Controlled clinical trial; Editorial Policies; Evidence‐Based Medicine [standards, *statistics & numerical data]; Funding; Guideline Adherence [statistics & numerical data]; Guidelines as Topic; Human; Humans; Medline; Parallel design; Periodicals as Topic [standards, *statistics & numerical data]; Practice guideline; PubMed; Randomized Controlled Trials as Topic [standards, *statistics & numerical data]; Randomized controlled trial; Research Design [standards, *statistics & numerical data]; Study design; Systematic Reviews as Topic; Systematic review -DOI: 10.1186/s13063-016-1713-6 -AB: Background: It is important that planned randomised trials are justified and placed in the context of the available evidence. The SPIRIT guidelines for reporting clinical trial protocols recommend that a recent and relevant systematic review should be included. The aim of this study was to assess the use of the existing evidence in order to justify trial conduct. Methods: Protocols of randomised trials published over a 1‐month period (December 2015) indexed in PubMed were obtained. Data on trial characteristics relating to location, design, funding, conflict of interest and type of evidence included for trial justification was extracted in duplicate and independently by two investigators. The frequency of citation of previous research including relevant systematic reviews and randomised trials was assessed. Results: Overall, 101 protocols for RCTs were identified. Most proposed trials were parallel‐group (n = 74; 73.3%). Reference to an earlier systematic review with additional randomised trials was found in 9.9% (n = 10) of protocols and without additional trials in 30.7% (n = 31), while reference was made to randomised trials in isolation in 21.8% (n = 22). Explicit justification for the proposed randomised trial on the basis of being the first to address the research question was made in 17.8% (n = 18) of protocols. A randomised controlled trial was not cited in 10.9% (95% CI: 5.6, 18.7) (n = 11), while in 8.9% (95% CI: 4.2, 16.2) (n = 9) of the protocols a systematic review was cited but did not inform trial design. Conclusions: A relatively high percentage of protocols of randomised trials involves prior citation of randomised trials, systematic reviews or both. However, improvements are required to ensure that it is explicit that clinical trials are justified and shaped by contemporary best evidence. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01288584/full - - -Record #135 of 151 -ID: CN-01711161 -AU: Breau RH -AU: Gaboury I -AU: Scales CD -AU: Fesperman SF -AU: Watterson JD -AU: Dahm P -TI: Reporting of Harm in Randomized Controlled Trials Published in the Urological Literature -SO: Journal of urology -YR: 2010 -VL: 183 -NO: 5 -PG: 1693‐1697 -PM: PUBMED 20299044 -XR: EMBASE 50832883 -PT: Journal article -KY: *adverse drug reaction; *postoperative complication /complication; Article; Bibliometrics; Cancer chemotherapy; Clinical trial; Controlled clinical trial; Data Interpretation, Statistical; Decision Making; Disease severity; Evidence‐Based Medicine; Human; Humans; Iatrogenic Disease; Information Storage and Retrieval [methods]; Medical Records [standards]; Medical documentation; Medical literature; Periodicals as Topic [*standards]; Postoperative Complications; Priority journal; Quality Assurance, Health Care; Randomized Controlled Trials as Topic; Randomized controlled trial; Research Design [standards]; Systematic review; Terminology as Topic; Unspecified side effect /side effect; Urologic Surgical Procedures; Urologic surgery -DOI: 10.1016/j.juro.2010.01.030 -AB: PURPOSE: Evidence‐based decision making seeks to balance potential benefits and harms (adverse effects) of health care interventions for an individual patient. We determined the prevalence and completeness of harm reporting in randomized controlled trials in the urological literature. MATERIALS AND METHODS: We performed a systematic literature search of all randomized controlled trials of therapeutic interventions published in The Journal of Urology, Urology, European Urology and BJU International in 1996 and 2004. Each article was reviewed by 2 independent investigators for 10 harm reporting criteria recommended by the CONSORT group. Discrepancies were settled by discussion and consensus. RESULTS: A total of 152 randomized controlled trials met the inclusion criteria, of which 109 (72%) reported adverse event outcomes. The median number of harm reporting criteria satisfied improved marginally from 1996 to 2004 (2.8 to 3.3, p = 0.36). A large proportion of studies failed to address harm in the abstract (55, 36%), introduction (71, 47%) and discussion (52, 34%). Few studies specified which adverse events were evaluated (21, 14%), when harm information was collected (32, 21%) or how the harm was attributed to the intervention (5, 3%). Only 48 (32%) articles provided reasons for patient withdrawal and 1 in 5 (33, 22%) reported the severity of adverse events. CONCLUSIONS: Randomized controlled trials published in the urological literature contain significant deficiencies in adverse event reporting. These findings suggest the need for reporting standards for harm in urological journals. Improvements in adverse event reporting would permit a more balanced assessment of interventions and would enhance evidence‐based urological practice. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01711161/full - - -Record #136 of 151 -ID: CN-01743156 -AU: Terwee CB -AU: Jansma EP -AU: Riphagen II -AU: de Vet HC -TI: Development of a methodological PubMed search filter for finding studies on measurement properties of measurement instruments -SO: Quality of life research -YR: 2009 -VL: 18 -NO: 8 -PG: 1115‐1123 -PM: PUBMED 19711195 -XR: EMBASE 50625627 -PT: Journal article -KY: *evidence based practice; *quality of life; Accuracy; Article; Bibliometrics; Clinical Laboratory Techniques; Clinical trial; Confidence Intervals; Controlled clinical trial; Controlled study; Data Collection; Data Mining [*statistics & numerical data]; Evidence‐Based Medicine [*methods]; Health Status Indicators; Human; Humans; Information Storage and Retrieval; Medline; Priority journal; Psychometrics; PubMed; Quality of Life; Randomized controlled trial; Reference Standards; Risk factor; Sensitivity analysis; Sensitivity and Specificity; Software [*statistics & numerical data]; Surveys and Questionnaires -DOI: 10.1007/s11136-009-9528-5 -AB: Objectives: For the measurement of patient‐reported outcomes, such as (health‐related) quality of life, often many measurement instruments exist that intend to measure the same construct. To facilitate instrument selection, our aim was to develop a highly sensitive search filter for finding studies on measurement properties of measurement instruments in PubMed and a more precise search filter that needs less abstracts to be screened, but at a higher risk of missing relevant studies. Methods: A random sample of 10,000 PubMed records (01‐01‐1990 to 31‐12‐2006) was used as a gold standard. Studies on measurement properties were identified using an exclusion filter and hand searching. Search terms were selected from the relevant records in the gold standard as well as from 100 systematic reviews of measurement properties and combined based on sensitivity and precision. The performance of the filters was tested in the gold standard as well as in two validation sets, by calculating sensitivity, precision, specificity, and number needed to read. Results: We identified 116 studies on measurement properties in the gold standard. The sensitive search filter was able to retrieve 113 of these 116 studies (sensitivity 97.4%, precision 4.4%). The precise search filter had a sensitivity of 93.1% and a precision of 9.4%. Both filters performed very well in the validation sets. Conclusion: The use of these search filters will contribute to evidence‐based selection of measurement instruments in all medical fields. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01743156/full - - -Record #137 of 151 -ID: CN-01733364 -AU: Matar HE -AU: Almerie MQ -AU: Al Marhi MO -AU: Adams CE -TI: Over 50 years of trial in Acta Psychiatrica Scandinavica: a survey -SO: Trials -YR: 2009 -VL: 10 -PG: 35 -PM: PUBMED 19473502 -XR: EMBASE 354999797 -PT: Journal article -KY: *Bibliometrics; *Periodicals as Topic [standards, statistics & numerical data]; *Psychiatry [economics, standards, statistics & numerical data]; *Randomized Controlled Trials as Topic [economics, standards, statistics & numerical data]; *Research Design [standards, statistics & numerical data]; *clinical study; *psychiatry; *publication; Adult; Article; Child; Clinical trial; Content analysis; Controlled clinical trial; Depression /therapy; Electroconvulsive therapy; Europe; Female; Guideline Adherence; Guidelines as Topic; Human; Humans; Information dissemination; Information processing; MEDLINE; Male; Medline; Mental Disorders [*therapy]; Outcome assessment; Patient Selection; Patient satisfaction; Psychotherapy; Quality Control; Quality control; Quality of life; Randomized controlled trial; Research Support as Topic; Sample Size; Sample size; Scandinavia; Scandinavian and Nordic Countries; Schizophrenia; Time Factors; Treatment Outcome -DOI: 10.1186/1745-6215-10-35 -AB: BACKGROUND: Randomised controlled trials are the gold standard for evaluating mental health care interventions. We assessed the content and quality of trials published in Acta Psychiatrica Scandinavica and Supplementum since 1948. METHODS: All trials were identified manually, quality assessed, data extracted, and sought on Medline. RESULTS: About 8.6% of all reports in the journal were clinical trials (n = 582) with the peak frequency in the 1980s. Most originate from Europe (80%) and focus on depression (approximately 38%) or schizophrenia (27%). The median sample size is 44. We found only two trials that fully met the criteria of quality reporting RCTs set by CONSORT statements (0.34%) since 1996. Less than 50% of records were possible to identify by a Medline search using broad methodological terms. CONCLUSION: Acta is a major source of health trials. The standard of reporting is similar to other journals but better adherence to CONSORT would ensure higher quality of reports and better dissemination. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01733364/full - - -Record #138 of 151 -ID: CN-01709375 -AU: Clifford TJ -AU: Barrowman NJ -AU: Moher D -TI: Funding source, trial outcome and reporting quality: are they related? Results of a pilot study -SO: BMC health services research -YR: 2002 -VL: 2 -NO: 1 -PG: 18 -PM: PUBMED 12213183 -XR: EMBASE 36478026 -PT: Journal article -KY: *Treatment Outcome; *financial management; *medical research; *treatment outcome; Article; Bibliometrics; Conflict of Interest; Disclosure; Drug Evaluation [*economics, standards]; Drug Industry; Humans; Medical literature; Organizations, Nonprofit; Periodicals as Topic [*standards, statistics & numerical data]; Pilot Projects; Pilot study; Publication Bias; Quality Control; Quality control; Randomized Controlled Trials as Topic [*economics, standards]; Randomized controlled trial; Reliability; Research Design [*standards]; Research Support as Topic [classification, *statistics & numerical data]; Research ethics; Scoring system; Statistical significance -DOI: 10.1186/1472-6963-2-18 -AB: Background: There has been increasing concern regarding the potential effects of the commercialization of research. Methods: In order to examine the relationships between funding source, trial outcome and reporting quality, recent issues of five peer‐reviewed, high impact factor, general medical journals were hand‐searched to identify a sample of 100 randomized controlled trials (20 trials/journal). Relevant data, including funding source (industry/not‐for‐profit/mixed/not reported) and statistical significance of primary outcome (favouring new treatment/favouring conventional treatment/neutral/unclear), were abstracted. Quality scores were assigned using the Jadad scale and the adequacy of allocation concealment. Results: Sixty‐six percent of trials received some industry funding. Trial outcome was not associated with funding source (p= .461). There was a preponderance of favourable statistical conclusions among published trials with 67% reporting results that favored a new treatment whereas 6% favoured the conventional treatment. Quality scores were not associated with funding source or trial outcome. Conclusions: It is not known whether the absence of significant associations between funding source, trial outcome and reporting quality reflects a true absence of an association or is an artefact of inadequate statistical power, reliance on voluntary disclosure of funding information, a focus on trials recently published in the top medical journals, or some combination thereof. Continued and expanded monitoring of potential conflicts is recommended, particularly in light of new guidelines for disclosure that have been endorsed by the ICMJE. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01709375/full - - -Record #139 of 151 -ID: CN-02598837 -AU: Zyoud SH -AU: Shakhshir M -AU: Abushanab AS -AU: Koni A -AU: Shahwan M -AU: Jairoun AA -AU: Abu Taha A -AU: Al-Jabi SW -TI: Unveiling the hidden world of gut health: exploring cutting-edge research through visualizing randomized controlled trials on the gut microbiota -SO: World journal of clinical cases -YR: 2023 -VL: 11 -NO: 26 -PG: 6132‐6146 -PM: PUBMED 37731574 -PT: Journal article -DOI: 10.12998/wjcc.v11.i26.6132 -AB: BACKGROUND: The gut microbiota plays a crucial role in gastrointestinal and overall health. Randomized clinical trials (RCTs) play a crucial role in advancing our knowledge and evaluating the efficacy of therapeutic interventions targeting the gut microbiota. AIM: To conduct a comprehensive bibliometric analysis of the literature on RCTs involving the gut microbiota. METHODS: Using bibliometric tools, a descriptive cross‐sectional investigation was conducted on scholarly publications concentrated on RCTs related to gut microbiota, spanning the years 2003 to 2022. The study used VOSviewer version 1.6.9 to examine collaboration networks between different countries and evaluate the frequently employed terms in the titles and abstracts of the retrieved publications. The primary objective of this analysis was to identify key research areas and focal points associated with RCTs involving the gut microbiota. RESULTS: A total of 1061 relevant articles were identified from the 24758 research articles published between 2003 and 2022. The number of publications showed a notable increase over time, with a positive correlation (R2 = 0.978, P < 0.001). China (n = 276, 26.01%), the United States (n = 254, 23.94%), and the United Kingdom (n = 97, 9.14%) were the leading contributing countries. Københavns Universitet (n = 38, 3.58%) and Dankook University (n = 35, 3.30%) were the top active institutions. The co‐occurrence analysis shows current gut microbiota research trends and important topics, such as obesity interventions targeting the gut microbiota, the efficacy and safety of fecal microbiota transplantation, and the effects of dietary interventions on humans. CONCLUSION: The study highlights the rapid growth and importance of research on RCTs that involve the gut microbiota. This study provides valuable insight into research trends, identifies key players, and outlines potential future directions in this field. Additionally, the co‐occurrence analysis identified important topics that play a critical role in the advancement of science and provided insights into future research directions in this field. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02598837/full - - -Record #140 of 151 -ID: CN-01942241 -AU: Smith J -AU: De Tonnerre E -AU: Spencer W -AU: Date P -AU: Taylor D -TI: Temporal trends in the publication of emergency medicine original research -SO: EMA - emergency medicine australasia -YR: 2019 -VL: 31 -PG: 13 -XR: EMBASE 627392308 -PT: Journal article; Conference proceeding -KY: *emergency medicine; *publication; Adult; Chi square test; Cohort analysis; Conference abstract; Conflict of interest; Controlled study; Funding; Human; Male; Randomized controlled trial; Retrospective study; Rigor; Sample size -DOI: 10.1111/1742-6723.13239 -AB: Background: Little is known about publication trends in emergency medicine research, with most reports being outdated.1 Objective: To determine temporal trends of 31 article characteristics, over a 20 year period. Methods: We undertook a retrospective review of journals with the highest impact factors. Original research articles were included if they were published in AnnEmergMed, AcadEmergMed, EurJEmergMed or EMJ in 1997, 2002, 2007, 2012 or 2017. Full‐text search functions allowed abstraction of bibliometric data. Kruskal‐Wallis and Chi square tests were employed. Results: 1,413 articles were examined. Between 1997 and 2017, author numbers increased and male authors decreased (Table). There were also increases (P < 0.01) in acronyms (6.8%‐16.1%), funding reports (20.2%‐71.2%) and conflicts of interest reports (0%‐96.1%). Study design, statistical analysis and reporting became more sophisticated (Table). However, the proportion of randomised trials decreased and cohort studies increased. There were increases (P < 0.01) in median sample sizes (365 to 1368.5), data collection periods (172‐674.5 days) and reference numbers (18.7‐28.2). Conclusion: Original research has increased its methodological rigor and reporting standards. However, there remains considerable scope for improvement. (Table Presented). -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01942241/full - - -Record #141 of 151 -ID: CN-02642406 -AU: Kim CK -AU: Kim DH -AU: Lee MS -AU: Kim JI -AU: Wieland LS -AU: Shin BC -TI: Randomized controlled trials on complementary and traditional medicine in the korean literature -SO: Evidence-based complementary and alternative medicine : eCAM -YR: 2014 -VL: 2014 -PG: 194047 -PM: PUBMED 25628747 -PT: Journal article -DOI: 10.1155/2014/194047 -AB: Objective. This study aimed to identify all of the features of complementary and alternative (CAM) randomized controlled trials (RCTs) in the Korean literature and then introduce English‐speaking researchers to the bibliometric and risk of bias characteristics of this literature. Methods. Eleven electronic databases and sixteen Korean journals were searched to August 2013 for RCTs of CAM therapies. Key study characteristics were extracted and risk of bias was assessed using the Cochrane Collaboration's tool for assessing risk of bias. Results. Three hundred and sixty publications met our inclusion criteria. Complementary and traditional medicine RCTs in the Korean literature emerged in the mid‐1990s and increased in the mid‐2000s. The most common CAM interventions include acupuncture (59.4%) and herbal medicine (8.3%). The largest proportion of trials evaluated CAM for musculoskeletal conditions (20.7%). Adequate methods of randomization were reported in 41.7% of the RCTs, whereas only 8.3% reported adequate allocation concealment. A low proportion of trials reported participant blinding (34.2%) and outcome assessor blinding (22.5%). Conclusions. Korean CAM RCTs are typically omitted from systematic reviews resulting in the potential for language bias. This study will enable these trials of diverse quality to be identified and assessed for inclusion in future systematic reviews on CAM interventions. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02642406/full - - -Record #142 of 151 -ID: CN-02597272 -AU: Guo YL -AU: Gao M -AU: Li H -AU: Zhou RJ -AU: Xu G -AU: Tang WC -AU: Wen JL -AU: Li SX -TI: Current status and trend of acupuncture-moxibustion for myofascial pain syndrome: a visual analysis of knowledge graph based on CiteSpace and VOSviewer -SO: Zhongguo zhen jiu [Chinese acupuncture & moxibustion] -YR: 2023 -VL: 43 -NO: 9 -CC: Complementary Medicine -PG: 996‐1005 -PM: PUBMED 37697873 -PT: Journal article -KY: *Acupuncture Therapy; *Electroacupuncture; *Moxibustion; *Myofascial Pain Syndromes [therapy]; Humans; Pattern Recognition, Automated -DOI: 10.13703/j.0255-2930.20230119-k0002 -AB: Bibliometric and scientific knowledge graph methods were used to analyze the research status and hot spots of acupuncture‐moxibustion in treatment of myofascial pain syndrome (MPS) and explore its development trend. The articles of both Chinese and English versions relevant to MPS treated by acupuncture‐moxibustion were searched in CNKI, VIP, Wanfang, SinoMed and WOS from the database inception to March 20, 2023. Using Excel2016, CiteSpace6.2.R2 and VOSviewer1.6.18, the visual analysis was conducted by means of the cooperative network, keyword co‐occurrence, keyword timeline, keyword emergence, etc. From Chinese databases and WOS database, 910 Chinese articles and 300 English articles were included, respectively. The annual publication volume showed an overall rising trend. Literature output of English articles was concentrated in Spain, China, and the United States, of which, there was less cross‐regional cooperation. In the keyword analysis, regarding acupuncture‐moxibustion therapy, Chinese articles focused on "acupuncture", "electroacupuncture" and "acupotomy"; while, "dry needling" and "injection" were dominated for English one. Clinical study was the current hot spot in Chinese databases, in comparison, the randomized controlled double‐blind clinical trial was predominant in WOS. Both Chinese and English articles were limited in the report of mechanism research. The cooperation among research teams should be strengthened to conduct comparative research, dose‐effect research and effect mechanism research with different methods of acupuncture‐moxibustion involved so that the evidences can be provided for deeper exploration. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02597272/full - - -Record #143 of 151 -ID: CN-02784329 -AU: Li M -AU: Jiang X -AU: Gai X -AU: Dai M -AU: Li M -AU: Wang Y -AU: Wang H -TI: CiteSpace-based visual analysis on transcutaneous electrical acupoint stimulation of clinical randomized controlled trial studies and its mechanism on perioperative disorders -SO: Medicine -YR: 2024 -VL: 103 -NO: 41 -PG: e39893 -PM: PUBMED 39465871 -XR: CINAHL 180511192 -PT: Journal article -KY: *Acupuncture Points; *Randomized Controlled Trials as Topic; *Transcutaneous Electric Nerve Stimulation [methods]; Humans; Perioperative Care [methods] -DOI: 10.1097/MD.0000000000039893 -AB: To systematically present an overview of randomized controlled trials on transcutaneous electrical acupoint stimulation (TEAS) using bibliometric methods, and describe the role and mechanisms of TEAS in most prevalent diseases. Relevant literature was searched in China National Knowledge Infrastructure, Wanfang Data, VIP, SinoMed, PubMed, and Web of Science. The literature was imported and screened into NoteExpress, screened according to inclusion and exclusion criteria, and analyzed using Excel and CiteSpace 6.3R1 software. A total of 1296 documents were included. The number of publications increased annually after 2012. Junlu Wang was the most prolific author. The main research institutions were Peking University, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Shuguang Hospital, and Tongde Hospital of Zhejiang Province. The research hotspots in this field include perioperative care, cancer, pain management, and stroke, primarily focusing on analgesia, immune enhancement, antihypertension, and reduction of gastrointestinal disorders. The main regulatory mechanisms of TEAS include the control of inflammation, oxidative stress, and regulation of the autonomic nervous system. TEAS is most widely used in the elderly, with PC6, ST36, and LI4 being the most frequently studied acupoints in clinical randomized controlled trials. The concept of accelerated rehabilitation is gradually being applied to TEAS, representing an emerging trend for future development. Clinical research on TEAS is rapidly developing, with a focus on applications in cancer and perioperative care. Future research should expand collaboration and conduct high‐level clinical and mechanistic studies, which will contribute to the development of standardized protocols and clinical practice. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02784329/full - - -Record #144 of 151 -ID: CN-02666472 -AU: Hawk LW -AU: Murphy TF -AU: Hartmann KE -AU: Burnett A -AU: Maguin E -TI: A randomized controlled trial of a team science intervention to enhance collaboration readiness and behavior among early career scholars in the Clinical and Translational Science Award network -SO: Journal of clinical and translational science -YR: 2024 -VL: 8 -NO: 1 -PG: e6 -PM: PUBMED 38384923 -PT: Journal article -DOI: 10.1017/cts.2023.692 -AB: INTRODUCTION: Despite the central importance of cross‐disciplinary collaboration in the Clinical and Translational Science Award (CTSA) network and the implementation of various programs designed to enhance collaboration, rigorous evidence for the efficacy of these approaches is lacking. We conducted a novel randomized controlled trial (RCT; ClinicalTrials.gov identifier: NCT05395286) of a promising approach to enhance collaboration readiness and behavior among 95 early career scholars from throughout the CTSA network. METHODS: Participants were randomly assigned (within two cohorts) to participate in an Innovation Lab, a week‐long immersive collaboration experience, or to a treatment‐as‐usual control group. Primary outcomes were change in metrics of self‐reported collaboration readiness (through 12‐month follow‐up) and objective collaboration network size from bibliometrics (through 21 months); secondary outcomes included self‐reported number of grants submitted and, among Innovation Lab participants only, reactions to the Lab experience (through 12 months). RESULTS: Short‐term reactions from Innovation Lab participants were quite positive, and controlled evidence for a beneficial impact of Innovation Labs over the control condition was observed in the self‐reported number of grant proposals in the intent‐to‐treat sample. Primary measures of collaboration readiness were near ceiling in both groups, limiting the ability to detect enhancement. Collaboration network size increased over time to a comparable degree in both groups. CONCLUSIONS: The findings highlight the need for systematic intervention development research to identify efficacious strategies that can be implemented throughout the CTSA network to better support the goal of enhanced cross‐disciplinary collaboration. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02666472/full - - -Record #145 of 151 -ID: CN-01940182 -AU: Lu C-L -AU: Li X -AU: Liu J-P -AU: Zhou H-M -AU: Zhang C -AU: Yang Y-Y -AU: Feng R-L -AU: Long C-J -AU: Deng F-Y -AU: Li J-C -AU: et al. -TI: Traditional Chinese Medicine in Cancer Care: an overview of randomized controlled trials published in Chinese -SO: Advances in integrative medicine -YR: 2019 -VL: 6 -PG: S108 -XR: EMBASE 2001763354 -PT: Journal article; Conference proceeding -KY: *Chinese medicine; *stomach cancer; Adult; Allopathy; Attention; Cancer patient; Clinical practice; Conference abstract; Controlled study; Drug combination; Female; General condition; Herbal medicine; Human; Lung cancer; Major clinical study; Male; Medline; Monotherapy; Publication; Quality of life; Randomized controlled trial; Satisfaction -DOI: 10.1016/j.aimed.2019.03.311 -AB: Background: Traditional Chinese medicine (TCM) has been widely integrated in cancer care in China. Large numbers of randomized controlled trials (RCTs) were published in Chinese literature, only did we report review since 2011. We aim to summarize the current evidence of relevant RCTs to support further clinical practice and research. Methods: Update was conducted in 4 main Chinese databases from the inception to June 2017 to identify RCTs. We bibliometrically analyzed the included RCTs and the research tendency of TCM for cancer. Results: 5835 RCTs (involving 477,150 participants) were included (Fig 1). Only 61 publications were indexed in MEDLINE. The top two cancer types treated were lung cancer and stomach cancer by study numbers and case numbers (Fig 2). 81.5% RCTs applied TCM combined with conventional treatment whilst 18.5% RCTs applied only TCM in treatment groups. Herbal medicine was the most frequently applied TCM therapy (5087 RCTs) (Table 1). 1237 RCTs reported multiple index as a composite outcome to measure cancer patients’ general condition. The most frequently reported outcome was clinical symptom improvement followed by quality of life, and biomarker indices (Fig 3). 4051 RCTs supported the better effect of TCM for cancer patients. Conclusions: Substantial data show different TCM treatments being applied either as monotherapy or in combination with conventional medicine for different cancer patients. It's significant to evaluate beneficial effect and safety of TCM treatments in the future. Real‐world research of TCM should pay more attention to patients’ quality of life and satisfaction. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01940182/full - - -Record #146 of 151 -ID: CN-02576213 -AU: Chander S -AU: Luhana S -AU: Sadarat F -AU: Leys L -AU: Parkash O -AU: Kumari R -TI: Gender and racial differences in first and senior authorship of high-impact critical care randomized controlled trial studies from 2000 to 2022 -SO: Annals of intensive care -YR: 2023 -VL: 13 -NO: 1 -PG: 56 -PM: PUBMED 37368060 -PT: Journal article -DOI: 10.1186/s13613-023-01157-2 -AB: BACKGROUND: Females and ethnic minorities are underrepresented in the first and senior authorships positions of academic publications. This stems from various structural and systemic inequalities and discrimination in the journal peer‐review process, as well as educational, institutional, and organizational cultures. METHODS: A retrospective bibliometric study design was used to investigate the representation of gender and racial/ethnic groups in the authorship of critical care randomized controlled trials in 12 high‐impact journals from 2000 to 2022. RESULTS: In the 1398 randomized controlled trials included in this study, only 24.61% of the first authors and 16.6% of the senior authors were female. Although female authorship increased during the study period, authorship was significantly higher for males throughout (Chi‐square for trend, p < 0.0001). The educational attainment [χ2(4) = 99.2, p < 0.0001] and the country of the author's affiliated institution [χ2(42) = 70.3, p = 0.0029] were significantly associated with gender. Male authorship was significantly more prevalent in 10 out of 12 journals analyzed in this study [χ2(11) = 110.1, p < 0.0001]. The most common race/ethnic group in our study population was White (85.1% women, 85.4% males), followed by Asians (14.3% females, 14.3% males). Although there was a significant increase in the number of non‐White authors between 2000 and 2022 [χ2(22) = 77.3, p < 0.0001], the trend was driven by an increase in non‐White male and not non‐White female authors. Race/ethnicity was significantly associated with the country of the author's affiliated institution [χ2(41) = 1107, p < 0.0001] but not with gender or educational attainment. CONCLUSIONS: Persistent gender and racial disparities in high‐impact medical and critical care journals underscore the need to revise policies and strategies to encourage greater diversity in critical care research. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02576213/full - - -Record #147 of 151 -ID: CN-02325658 -AU: Mohanty CR -AU: Bellapukonda S -AU: Mund M -AU: Behera BK -AU: Sahoo SS -TI: Analysis of publication speed of anesthesiology journals: a cross-sectional study -SO: Brazilian journal of anesthesiology -YR: 2021 -VL: 71 -NO: 2 -PG: 110‐115 -PM: PUBMED 33731261 -XR: EMBASE 635871639 -PT: Journal article -KY: *anesthesiology; *cross‐sectional study; *journal impact factor; *peer review; *velocity; Anesthesiology; Article; Controlled study; Cross‐Sectional Studies; Human; Medline; Periodicals as Topic; Randomized controlled trial; Retrospective Studies; Retrospective study -DOI: 10.1016/j.bjane.2021.02.025 -AB: BACKGROUND: Publication speed is one of the critical factors affecting authors' preference to a journal for manuscript submission. The publication time of submitted manuscripts varies across journals and specialty. OBJECTIVES: Several bibliometric studies in various fields of medicine, except in anesthesiology, have addressed the issue of publication speed and factors that influence the publication speed. We aimed to identify factors affecting the publication speed of indexed anesthesiology journals. METHOD: Overall, 25 anesthesiology journals indexed in MEDLINE database were retrospectively analyzed for the time required during different stages of publication process. A total of 12 original articles published in the year 2018 were randomly selected from each journal based on the number of issues. Time periods from submission to acceptance and from submission to publication were noted, and their association with impact factor (IF), advanced online publication (AOP), and article processing charges (APCs) were evaluated. RESULTS: The median time from submission to acceptance and from submission to publication for the selected journals were 120 (IQR [83‐167]) days and 186 (IQR [126‐246]) days, respectively. Publication speed was not found to have any correlation with IF and APC. However, journals with AOP required significantly lesser time for publication than those without AOP 138.5 and 240 days, respectively, (p�=� 0.011). Moreover, the IF of journals with AOP was significantly higher than that of journals without AOP (p�=� 0.002). CONCLUSION: The study provides an overview of total time required for peer review, acceptance, and publication in indexed anesthesiology journals. Researchers should focus on journals with AOP for expediting the publication process and avoiding publication delays. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02325658/full - - -Record #148 of 151 -ID: CN-02647042 -AU: Shaqman M -AU: Al-Abedalla K -AU: Wagner J -AU: Swede H -AU: Gunsolley JC -AU: Ioannidou E -TI: Reporting quality and spin in abstracts of randomized clinical trials of periodontal therapy and cardiovascular disease outcomes -SO: PloS one -YR: 2020 -VL: 15 -NO: 4 -PG: e0230843 -PM: PUBMED 32302309 -PT: Journal article -DOI: 10.1371/journal.pone.0230843 -AB: OBJECTIVE: Poor reporting in randomized clinical trial (RCT) abstracts reduces quality and misinforms readers. Spin, a biased presentation of findings, could frequently mislead clinicians to accept a clinical intervention despite non‐significant primary outcome. Therefore, good reporting practices and absence of spin enhances research quality. We aim to assess the reporting quality and spin in abstracts of RCTs evaluating the effect of periodontal therapy on cardiovascular (CVD) outcomes. METHODS: PubMed, Scopus, the Cochrane Central Register of Controlled Trials (CENTRAL), and 17 trial registration platforms were searched. Cohort, non‐randomized, non‐English studies, and pediatric studies were excluded. RCT abstracts were reviewed by 2 authors using the CONSORT for abstracts and spin checklists for data extraction. Cohen's Kappa statistic was used to assess inter‐rater agreement. Data on the selected RCT publication metrics were collected. Descriptive analysis was performed with non‐parametric methods. Correlation analysis between quality, spin and bibliometric parameters was conducted. RESULTS: 24 RCTs were selected for CONSORT analysis and 14 fulfilled the criteria for spin analysis. Several important RCT elements per CONSORT were neglected in the abstract including description of the study population (100%), explicitly stated primary outcome (87%), methods of randomization and blinding (100%), trial registration (87%). No RCT examined true outcomes (CVD events). A significant fraction of the abstracts appeared with at least one form of spin in the results and conclusions (86%) and claimed some treatment benefit in spite of non‐significant primary outcome (64%). High‐quality reporting had a significant positive correlation with reporting of trial registration (p = 0.04) and funding (p = 0.009). Spinning showed marginal negative correlation with reporting quality (p = 0.059). CONCLUSION: Poor adherence to the CONSORT guidelines and high levels of data spin were found in abstracts of RCTs exploring the effects of periodontal therapy on CVD outcomes. Our findings indicate that journal editors and reviewers should consider strict adherence to proper reporting guidelines to improve reporting quality and reduce waste. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02647042/full - - -Record #149 of 151 -ID: CN-01728197 -AU: Su C-X -AU: Zhang K -AU: Liang N -AU: Li W-Y -AU: Sun J -AU: Liu T-K -AU: Yue S-J -AU: Liu J-P -TI: Randomized clinical trials on acupuncture published in english: a systematic literature review -SO: Journal of alternative and complementary medicine (New York, N.Y.) -YR: 2016 -VL: 22 -NO: 6 -CC: Complementary Medicine -PG: A42‐A43 -XR: EMBASE 611808117 -PT: Journal article; Conference proceeding -KY: *acupuncture; China; Cochrane Library; Connective tissue disease; Controlled clinical trial; Controlled study; Embase; Human; Medline; Musculoskeletal disease; Parallel design; Publication; Randomized controlled trial; Registration; Safety; Systematic review -DOI: 10.1089/acm.2016.29003.abstracts -AB: Purpose: To systematically evaluate the characteristics and quality of randomized clinical trials (RCTs) on acupuncture published in English. Methods: We systematically searched PubMed, EMBASE and Cochrane Library from their inception to February 2014 to identify RCTs on acupuncture and to bibliometrically analyze the included trials. The methodological quality and reporting quality of RCTs were assessed using the Cochrane risk of bias tool and STRICTA, respectively. Results: A total of 855 RCTs (involving 109, 698 participants) were included and published from 1975 to 2014. The number of publications showed a sustained growth, especially after 2006. The included trials originated from 35 different countries, with major proportion from China (26.1%) and USA (13.2%). 39.5% RCTs were published in complementary and alternative medical journals and only 6.2% were in high rank Journals (impact factor >10). The majority were single‐center (65.9%), parallel‐group (91.7%), twoarms (69.1%), superiority design (81.2%) and placebo/sham‐controlled (58.8%). The most frequent condition was musculoskeletal and connective tissue diseases (21.8%). Only 111 (13.0%) provided the information on trial registration. 368 (43.0%) specified the primary and secondary outcome. 695 (81.3%) reported clinical relevant outcomes while only 20.7% and 6.1% reported safety and health‐economic outcomes, respectively. Generally, the methodology of included trials was insufficiently reported. Only 49.7%, 39.0%, 66.6% reported generation of allocation sequence, allocation concealment and blinding, respectively. Incomplete outcome reporting and selective outcome reporting existed in 10.8% and 14.7%, respectively. Furthermore, the reporting quality of acupuncture intervention was poor. Only three articles provided detailed information on all the items of STRICTA. The least reported item was“Extent to which treatment was varied”(14.4%). Conclusion: The quantity of RCTs on acupuncture is substantial and increasing, but the methodological quality and reporting quality of RCTs are generally suboptimal. Future RCTs on acupuncture would need to be reported based on the CONSORT and STRICTA Statements. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01728197/full - - -Record #150 of 151 -ID: CN-02132700 -AU: Stokkeland K -AU: Wannerholt A -AU: Leifman A -AU: Franck J -AU: Soderman C -TI: MINIMAL ALCOHOL INTERVENTION IN PATIENTS WITH ESOPHAGEAL VARICES - A RANDOMIZED CONTROLLED TRIAL -SO: Gastroenterology -YR: 2020 -VL: 158 -NO: 6 -CC: Drugs and Alcohol -PG: S‐1474 -XR: EMBASE 2005916223 -PT: Journal article; Conference proceeding -KY: *esophagus varices; Addiction Severity Index; Adult; Alcohol liver disease; Alcoholism; Chronic liver disease; Clinical trial; Cohort analysis; Conference abstract; Controlled study; Female; Follow up; Gender; Human; Interview; Kaplan Meier method; Liver cirrhosis; Major clinical study; Male; Mortality; Outcome assessment; Private hospital; Psychiatric diagnosis; Randomization; Randomized controlled trial; Risk reduction; Statistical significance; Survival time -DOI: 10.1016/S0016-5085(20)34345-6 -AB: For patients with a chronic liver disease with affected liver function the pharmacological treatment alternatives are severely restricted because of the risk of accelerating liver failure. The treatment options for alcohol use disorder in chronic liver diseases are therefore currently mostly restricted to non‐pharmacological treatment. The non‐pharmacological strategies proposed to reduce excessive drinking regularly fall within the category of brief intervention. Esophageal varices occurs in 10‐15% of patients with compensated cirrhosis. When esophageal varices bleeds the 6‐weeks mortality is 15‐20%. The aim of our study was to study the impact of minimal intervention regarding alcohol consumption on mortality in patients with esophageal varices caused by chronic liver diseases. Methods: We randomized 99 patients with esophageal varices caused by chronic liver diseases from a Swedish private hospital. The study period was between November 2014 and July 2017. We excluded patients with severe psychiatric diagnoses and enchephalopaty that rendered interviewing impossible. Bibliometric and clinical data was recorded and patients were interviewed with Alcohol Use Disorder Test and Addiction Severity Index before randomization to brief intervention (n= 49) and no intervention (n=50). We followed all participants for 2 years with interviews regarding their alcohol use every 3 months. Our primary outcome for the study was mortality. Results: We found that 10 patients who received intervention deceased during follow‐up compared to 15 in the control group (RR=0.88, p=0.35). The mean survival time in the intervention group was 623.0 days (4‐730 days) compared to 621.6 days (16‐736 days). There were no significant differences between the intervention group and the control group when the groups were stratified for gender, alcoholic liver disease or non‐alcoholic liver disease. The survival is presented as a Kaplan‐Meier curve in figure 1 In conclusion we found a difference in survival between patients with esophageal varices caused by chronic liver diseases who had undergone minimal alcohol intervention compared to controls which did not reach statistical significance. The 12 % risk reduction might be caused by chance. A larger study cohort may elucidate the true role of brief intervention in patients with severe liver disease. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02132700/full - - -Record #151 of 151 -ID: CN-02646220 -AU: Han M -AU: Lai L -AU: Li XX -AU: Zhao NQ -AU: Li J -AU: Xia Y -AU: Liu JP -TI: An Overview of the Randomized Placebo-Controlled Trials of Chinese Herbal Medicine Formula Granules -SO: Evidence-based complementary and alternative medicine : eCAM -YR: 2019 -VL: 2019 -CC: Complementary Medicine -PG: 6486293 -PM: PUBMED 31110552 -PT: Journal article -DOI: 10.1155/2019/6486293 -AB: OBJECTIVE: To summarize the characteristics and the outcomes of the Randomized Placebo‐Controlled Trials of Chinese Herbal Medicine Granules manufactured by China Resources Sanjiu Pharmaceutical Co., Ltd. METHODS: Databases including China National Knowledge Infrastructure, VIP, Wanfang, PubMed, Cochrane Library, and clinicaltrials.gov were searched in March 2018 for relevant randomized controlled trials (RCTs). Two reviewers independently screened for and selected studies, extracted data, and checked data extraction. Methodological quality was evaluated using the Cochrane Risk of Bias tool. For the outcome, the characteristics of the study, the cure rate, the effectiveness rate, and advert events were described with a method of bibliometrics. Also, we performed meta‐analysis only if there were ≥2 studies treated by the same intervention and evaluated by the same outcome. CONCLUSION: 16 of 19 studies treated by CHM granules only showed positive result in 7 diseases and negative result in 1 disease. 17 of 21 studies treated by combination therapy against conventional therapy showed positive result in 6 diseases and negative result in 3 diseases. However, both the absolute and relative effectiveness of CHM formula granules compared with placebo need to be considered clinically. RESULTS: A total of 40 placebo‐controlled RCTs treated for 17 diseases were included in our analysis involving 4,632 patients. 16 of 19 studies treated by CHM granules only showed positive result in patients with HBV, HCV, fever, depression, nonalcoholic fatty liver disease, AIDS, and asthma while negative result was shown in patients with migraine. 17 of 21 studies treated by combination therapy against conventional therapy showed positive result in patients with HBV, herpes simplex keratitis, COPD, liver cirrhotic ascites, Parkinson's disease, and diabetic peripheral neuropathy while negative result was shown in patients with myasthenia gravis, angina pectoris, and depression. The pooled result cannot demonstrate that the notifying kidney formula granules had the superior effect with placebo on the clearance of serum HBV DNA and HBeAg in HBV carriers with a RR (and the 95% CI) of 2.97 [0.74,11.91] and 1.99 [0.93,4.29], respectively. But, the CHM granules can reduce within‐group HBV DNA levels by more than 2 lgIU/ml; the RR (and 95% CI) was 4.64 [2.89,7.45]. Qizhu granules had a significant effect on clearance of HCV RNA with a RR (and 95% CI) of 6.26 [2.16,18.16]. And, the heat‐clearing and detoxifying formula granules were superior to placebo in resolution of cold symptom among patients with fever with a RR and 95% CI of 2.58 [1.40,4.74]. Based on the conventional therapy, the pooled result demonstrated that the Regulating liver formula granules were superior to placebo on the clearance of serum HBeAg in chronic hepatitis B patients with a RR (and the 95% CI) of 1.73 [1.30,2.31]. The EeChen decoction granules were superior to placebo in COPD patients with a RR (and the 95% CI) of 1.13 [1.06,1.22]. 28 of the 40 studies reported adverse events. There were 51 adverse events in CHM formula granules group or combination group (n=2,483) and 26 in control group (n=2,122) totally. Most of the adverse symptoms spontaneously resolved after completing the courses of treatment and the other adverse symptoms improved after symptomatic treatment. -US: https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02646220/full - - diff --git a/sources/new/PUBMED/BiblioshinyReport-2025-07-14.xlsx b/sources/new/PUBMED/BiblioshinyReport-2025-07-14.xlsx deleted file mode 100644 index df072e71b..000000000 Binary files a/sources/new/PUBMED/BiblioshinyReport-2025-07-14.xlsx and /dev/null differ diff --git a/sources/new/PUBMED/pubmed-coronaryhe-set.txt b/sources/new/PUBMED/pubmed-coronaryhe-set.txt deleted file mode 100644 index e63c28f8d..000000000 --- a/sources/new/PUBMED/pubmed-coronaryhe-set.txt +++ /dev/null @@ -1,102123 +0,0 @@ -PMID- 17352852 -OWN - NLM -STAT- MEDLINE -DCOM- 20070525 -LR - 20190917 -IS - 1579-2242 (Electronic) -IS - 0300-8932 (Linking) -VI - 60 Suppl 1 -DP - 2007 Feb -TI - [Ischemic heart disease: 2006 update]. -PG - 3-18 -AB - This article contains a review of the main developments reported in publications - and conference presentations in 2006 on the pathophysiology, secondary - prevention, prognosis, and treatment of ST-segment elevation and non-ST-segment - elevation acute coronary syndrome. The latest clinical practice guidelines are - also discussed. -FAU - García-Moll, Xavier -AU - García-Moll X -AD - Servicio de Cardiología, Hospital de la Santa Creu i Sant Pau, Barcelona, España. - xgarcia-moll@santpau.es -FAU - Bardají, Alfredo -AU - Bardají A -FAU - Alonso, Joaquín -AU - Alonso J -FAU - Bueno, Héctor -AU - Bueno H -LA - spa -PT - English Abstract -PT - Journal Article -PT - Review -TT - Actualización en cardiopatía isquémica 2006. -PL - Spain -TA - Rev Esp Cardiol -JT - Revista espanola de cardiologia -JID - 0404277 -SB - IM -MH - Acute Disease -MH - Angina, Unstable/diagnosis/therapy -MH - Humans -MH - Myocardial Infarction/physiopathology/therapy -MH - *Myocardial Ischemia/complications/diagnosis/physiopathology/therapy -MH - Myocardial Reperfusion -MH - Syndrome -RF - 62 -EDAT- 2007/03/14 09:00 -MHDA- 2007/05/26 09:00 -CRDT- 2007/03/14 09:00 -PHST- 2007/03/14 09:00 [pubmed] -PHST- 2007/05/26 09:00 [medline] -PHST- 2007/03/14 09:00 [entrez] -AID - 13099709 [pii] -AID - 10.1157/13099709 [doi] -PST - ppublish -SO - Rev Esp Cardiol. 2007 Feb;60 Suppl 1:3-18. doi: 10.1157/13099709. - -PMID- 23961914 -OWN - NLM -STAT- MEDLINE -DCOM- 20150130 -LR - 20191112 -VI - 8 -IP - 3 -DP - 2013 Dec -TI - Ranolazine: effects on ischemic heart. -PG - 197-203 -AB - Coronary artery disease is the major cause of mortality and morbidity in the - industrialized countries; in the United States of America and in Europe, it is - responsible for one of every six deaths per year. In the setting of ischemic - heart disease, angina pectoris and chest pain, in particular, are the major - causes of emergency department accesses. Angina pectoris is a clinical syndrome - characterized by discomfort typically in the chest, neck, chin and left arm - induced by physical exertion, emotional stress and cold and is relieved by rest - or by taking of nitrates. The main targets of treatment of angina pectoris are to - improve quality of life by reducing the frequency and the severity of symptoms, - to increase functional capacity and to improve prognosis. Ranolazine is a recent - antianginal drug with unique methods of action. It was approved by the US Food - and Drug Administration in 2006 as add-on therapy in patients symptomatic for - stable angina. With the inhibition of the late sodium current, Ranolazine - protects against ion deregulation, prevents cellular calcium overload and the - subsequent increase in diastolic tension without impacting heart rate and blood - pressure. Short term clinical trials and patent research show that add on therapy - with Ranolazine in patients with chronic stable angina significantly improves - exercise duration, exercise time to angina and reduces the use of nitro - glycerine. Long term clinical trials showed no significant differences in the - rate of cardiovascular death and myocardial infarction in patients with non-ST - segment elevation acute coronary syndromes but a reduction in terms of recurrent - ischemia. Ranolazine is generally well tolerated and even if it increases the - duration of QTc interval it is not associated with atrial and ventricular - arrhythmias. Therefore Ranolazine represents a good therapeutic approach in - patients with chronic stable angina still symptomatic, while on optimal - anti-ischemic therapy, or intolerant to traditional anti-ischemic drugs. -FAU - Rognoni, Andrea -AU - Rognoni A -FAU - Barbieri, Lucia -AU - Barbieri L -FAU - Cavallino, Chiara -AU - Cavallino C -FAU - Bacchini, Sara -AU - Bacchini S -FAU - Veia, Alessia -AU - Veia A -FAU - Degiovanni, Anna -AU - Degiovanni A -FAU - Rametta, Francesco -AU - Rametta F -FAU - Nardi, Federico -AU - Nardi F -FAU - Lazzero, Maurizio -AU - Lazzero M -FAU - Lupi, Alessandro -AU - Lupi A -FAU - Bongo, Angelo S -AU - Bongo AS -AD - Coronary Care Unit and Catheterization Laboratory, "Maggiore della Carita" - Hospital, Corso Mazzini 18, 28100 Novara, Italy. arognoni@hotmail.com. -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Recent Pat Cardiovasc Drug Discov -JT - Recent patents on cardiovascular drug discovery -JID - 101263805 -RN - 0 (Acetanilides) -RN - 0 (Piperazines) -RN - 0 (Sodium Channel Blockers) -RN - A6IEZ5M406 (Ranolazine) -SB - IM -MH - Acetanilides/adverse effects/pharmacokinetics/pharmacology/*therapeutic use -MH - Angina, Stable/drug therapy -MH - Animals -MH - Arrhythmias, Cardiac/drug therapy -MH - Clinical Trials as Topic -MH - Diabetes Mellitus/drug therapy -MH - Drug Interactions -MH - Heart Failure/drug therapy -MH - Humans -MH - Myocardial Ischemia/*drug therapy -MH - Piperazines/adverse effects/pharmacokinetics/pharmacology/*therapeutic use -MH - Ranolazine -MH - Sodium Channel Blockers/*therapeutic use -EDAT- 2013/08/22 06:00 -MHDA- 2015/01/31 06:00 -CRDT- 2013/08/22 06:00 -PHST- 2013/07/01 00:00 [received] -PHST- 2013/08/13 00:00 [revised] -PHST- 2013/08/19 00:00 [accepted] -PHST- 2013/08/22 06:00 [entrez] -PHST- 2013/08/22 06:00 [pubmed] -PHST- 2015/01/31 06:00 [medline] -AID - PRC-EPUB-55322 [pii] -AID - 10.2174/15748901113089990023 [doi] -PST - ppublish -SO - Recent Pat Cardiovasc Drug Discov. 2013 Dec;8(3):197-203. doi: - 10.2174/15748901113089990023. - -PMID- 17658266 -OWN - NLM -STAT- MEDLINE -DCOM- 20080214 -LR - 20250623 -IS - 1010-7940 (Print) -IS - 1010-7940 (Linking) -VI - 32 -IP - 3 -DP - 2007 Sep -TI - Predictors of mortality after aortic valve replacement. -PG - 469-74 -AB - Aortic valve replacement (AVR) is recommended as a standard surgical procedure - for aortic valve disease. Still the evidence for commonly claimed predictors of - post-AVR prognosis, in particular mortality, appears scant. This systematic - review reports on the evidence for predictors of post-AVR mortality, and may be - helpful in pre-surgical risk-stratification. In PubMed, we searched for original - reports of post-AVR follow-up studies. We assessed the quality of study design - and methods with a standardized checklist. Data of the reported predictors of - mortality and outcomes were extracted. Twenty-eight studies met our inclusion - criteria. Sixteen studies were considered of high quality. There is strong - evidence that the risk of early mortality is increased by emergency surgery, - while the risk of late mortality is increased with older age and preoperative - atrial fibrillation. There is moderate evidence that the risk of early mortality - is increased by older age, aortic insufficiency, coronary artery disease, longer - cardiopulmonary bypass time, reduced left ventricular ejection fraction (LV-EF), - infective endocarditis, hypertension, mechanical valves, preoperative pacing, - dialysis-dependent renal failure and valve size; and that the risk for late - mortality is increased by emergency surgery and urgency of the operation. There - is little evidence for high New York Heart Association class, concomitant - coronary artery bypass graft and many other commonly claimed risk factors for - post-AVR mortality. The reported evidence on predictors of post-AVR mortality - will help for pre-surgical risk-stratification, i.e. to discern patients at high - or low risk for early and late post-AVR mortality. Future prognostic studies - should take the evidence from this review into account and should focus on - derivation of a predictive model for post-AVR survival. -FAU - Tjang, Yanto Sandy -AU - Tjang YS -AD - Julius Center of Health Sciences and Primary Care, University Medical Center, - Utrecht, The Netherlands. ystjang@hotmail.com -FAU - van Hees, Yvonne -AU - van Hees Y -FAU - Körfer, Reiner -AU - Körfer R -FAU - Grobbee, Diederick E -AU - Grobbee DE -FAU - van der Heijden, Geert J M G -AU - van der Heijden GJ -LA - eng -PT - Journal Article -PT - Systematic Review -DEP - 20070719 -PL - Germany -TA - Eur J Cardiothorac Surg -JT - European journal of cardio-thoracic surgery : official journal of the European - Association for Cardio-thoracic Surgery -JID - 8804069 -SB - IM -MH - Adult -MH - Age Factors -MH - Aged -MH - Aged, 80 and over -MH - *Aortic Valve -MH - Emergencies -MH - Female -MH - Heart Valve Diseases/mortality/*surgery -MH - Heart Valve Prosthesis/*adverse effects -MH - Heart Valve Prosthesis Implantation/mortality -MH - Humans -MH - Male -MH - Middle Aged -MH - Multivariate Analysis -MH - Postoperative Complications/*mortality -MH - Prognosis -MH - Risk Assessment -MH - Risk Factors -MH - Survival Analysis -RF - 44 -EDAT- 2007/07/31 09:00 -MHDA- 2008/02/15 09:00 -CRDT- 2007/07/31 09:00 -PHST- 2007/03/20 00:00 [received] -PHST- 2007/06/01 00:00 [revised] -PHST- 2007/06/11 00:00 [accepted] -PHST- 2007/07/31 09:00 [pubmed] -PHST- 2008/02/15 09:00 [medline] -PHST- 2007/07/31 09:00 [entrez] -AID - S1010-7940(07)00537-4 [pii] -AID - 10.1016/j.ejcts.2007.06.012 [doi] -PST - ppublish -SO - Eur J Cardiothorac Surg. 2007 Sep;32(3):469-74. doi: 10.1016/j.ejcts.2007.06.012. - Epub 2007 Jul 19. - -PMID- 17700380 -OWN - NLM -STAT- MEDLINE -DCOM- 20070906 -LR - 20121115 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 15 -IP - 5 -DP - 2007 Sep-Oct -TI - Valvular aortic stenosis in the elderly. -PG - 217-25 -AB - Elderly patients with valvular aortic stenosis have an increased prevalence of - coronary risk factors, of coronary artery disease, and evidence of other - atherosclerotic vascular diseases. Statins may reduce the progression of aortic - stenosis (AS). Angina pectoris, syncope or near syncope, and congestive heart - failure are the 3 classic manifestations of severe AS. Prolonged duration and - late peaking of an aortic systolic ejection murmur best differentiate severe AS - from mild AS on physical examination. Doppler echocardiography is used to - diagnose the prevalence and severity of AS. The indications for cardiac - catheterization and the medical management of AS are discussed. Once symptoms - develop, aortic valve replacement (AVR) should be performed in patients with - severe or moderate AS. Other indications for AVR are discussed. Warfarin should - be administered indefinitely after AVR in patients with a mechanical aortic valve - and in patients with a bioprosthetic aortic valve who have either atrial - fibrillation, prior thromboembolism, left ventricular systolic dysfunction, or a - hypercoagulable condition. Patients with a bioprosthetic aortic valve without any - of these 4 risk factors should be treated with aspirin 75-100 mg daily. -FAU - Aronow, Wilbert S -AU - Aronow WS -AD - Cardiology Division, Department of Medicine, New York Medical College, Valhalla, - New York 10595, USA. wsaronow@aol.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Fibrinolytic Agents) -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Angina Pectoris/epidemiology -MH - Antibiotic Prophylaxis -MH - *Aortic Valve Stenosis/diagnosis/epidemiology/physiopathology/therapy -MH - Cardiac Catheterization -MH - Catheterization -MH - Comorbidity -MH - Echocardiography, Doppler -MH - Electrocardiography -MH - Endocarditis, Bacterial/prevention & control -MH - Fibrinolytic Agents/therapeutic use -MH - Heart Failure/epidemiology/physiopathology -MH - Heart Valve Prosthesis Implantation -MH - Humans -MH - Hypertrophy, Left Ventricular/epidemiology -MH - Prevalence -RF - 99 -EDAT- 2007/08/19 09:00 -MHDA- 2007/09/07 09:00 -CRDT- 2007/08/19 09:00 -PHST- 2007/08/19 09:00 [pubmed] -PHST- 2007/09/07 09:00 [medline] -PHST- 2007/08/19 09:00 [entrez] -AID - 00045415-200709000-00001 [pii] -AID - 10.1097/CRD.0b013e31805f6796 [doi] -PST - ppublish -SO - Cardiol Rev. 2007 Sep-Oct;15(5):217-25. doi: 10.1097/CRD.0b013e31805f6796. - -PMID- 16555862 -OWN - NLM -STAT- MEDLINE -DCOM- 20061017 -LR - 20181025 -IS - 1175-3277 (Print) -IS - 1175-3277 (Linking) -VI - 6 -IP - 2 -DP - 2006 -TI - Preventing cardiovascular disease in the 21st century: therapeutic and preventive - implications of current evidence. -PG - 87-101 -AB - Cardiovascular disease (CVD), particularly coronary heart disease (CHD), remains - a major cause of mortality, morbidity, and disability in the US and other - Westernized societies. As a result of therapeutic and preventive measures to - control the CVD/CHD epidemic, mortality has declined steadily during the last - several decades with a consequent gain in life expectancy, but the 1990s - witnessed a slowing of this decline. In response to these trends, a range of - therapeutic regimens were developed to address adverse CVD risk factor levels and - their deleterious effects. The scientific evidence regarding the efficacy, cost - effectiveness, strengths, and limitations of a range of pharmacologic and - lifestyle approaches to CVD prevention--both primary and secondary--are reviewed - in depth. Clinical trials aimed at primary and secondary prevention of CVD have - documented the efficacy and cost effectiveness of various drugs in lowering - individual risk factor levels and in reducing clinical CVD events. More recently, - the idea of a 'polypill' containing low doses of multiple drugs has generated - much interest, with proponents arguing that, given the high prevalence of CVD - risk factors and the effectiveness of pharmacologic interventions, such a drug - combination would reduce CHD mortality by 88% if taken by all individuals aged > - or = 55 years. However, current treatments to control high BP and serum - cholesterol, while effective, do not typically reduce morbidity and mortality to - levels observed in low-risk individuals, i.e. those with favorable levels of all - readily measured major risk factors. Rather, primary prevention of all major risk - factors starting early in life is critical. Prospective population-based research - has delineated multiple long-term benefits associated with low-risk status in - young adulthood and middle age, i.e. markedly lower age-specific CVD and total - mortality rates, increased life expectancy, lower healthcare costs, lower - medication use and prevalence of chronic diseases, and higher self-reported - quality of life at older ages. Unfortunately, despite declines in the prevalence - of most major CVD risk factors, low-risk status remains rare among US adults. - Data have also demonstrated that adverse levels of one or more major risk factors - precede clinical CHD in 90% or more of all cases, undermining the assertion that - major CVD risk factors account for 'no more than 50%' of CHD cases. Hence, while - numerous treatment options exist for secondary prevention of CVD, strategies that - focus on progressively increasing the proportion of low-risk individuals could - greatly reduce the need for secondary prevention in the first place. Public - health policies must focus on prevention of all major risk factors - simultaneously, using lifestyle approaches from early ages onwards to reduce - population CVD risk to endemic levels, rather than current epidemic levels. -FAU - Daviglus, Martha L -AU - Daviglus ML -AD - Department of Preventive Medicine, Feinberg School of Medicine, Northwestern - University, Chicago, Illinois 60611, USA. daviglus@northwestern.edu -FAU - Lloyd-Jones, Donald M -AU - Lloyd-Jones DM -FAU - Pirzada, Amber -AU - Pirzada A -LA - eng -GR - HL21010/HL/NHLBI NIH HHS/United States -GR - R01 HL62684/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -SB - IM -MH - Cardiovascular Diseases/*drug therapy/*prevention & control -MH - Drug Therapy/methods/trends -MH - Drug Therapy, Combination -MH - Humans -MH - Life Style -MH - Primary Prevention/methods/trends -RF - 113 -EDAT- 2006/03/25 09:00 -MHDA- 2006/10/18 09:00 -CRDT- 2006/03/25 09:00 -PHST- 2006/03/25 09:00 [pubmed] -PHST- 2006/10/18 09:00 [medline] -PHST- 2006/03/25 09:00 [entrez] -AID - 623 [pii] -AID - 10.2165/00129784-200606020-00003 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2006;6(2):87-101. doi: 10.2165/00129784-200606020-00003. - -PMID- 21676245 -OWN - NLM -STAT- MEDLINE -DCOM- 20120301 -LR - 20250608 -IS - 1749-799X (Electronic) -IS - 1749-799X (Linking) -VI - 6 -DP - 2011 Jun 15 -TI - Effects of obesity on bone metabolism. -PG - 30 -LID - 10.1186/1749-799X-6-30 [doi] -AB - Obesity is traditionally viewed to be beneficial to bone health because of - well-established positive effect of mechanical loading conferred by body weight - on bone formation, despite being a risk factor for many other chronic health - disorders. Although body mass has a positive effect on bone formation, whether - the mass derived from an obesity condition or excessive fat accumulation is - beneficial to bone remains controversial. The underline pathophysiological - relationship between obesity and bone is complex and continues to be an active - research area. Recent data from epidemiological and animal studies strongly - support that fat accumulation is detrimental to bone mass. To our knowledge, - obesity possibly affects bone metabolism through several mechanisms. Because both - adipocytes and osteoblasts are derived from a common multipotential mesenchymal - stem cell, obesity may increase adipocyte differentiation and fat accumulation - while decrease osteoblast differentiation and bone formation. Obesity is - associated with chronic inflammation. The increased circulating and tissue - proinflammatory cytokines in obesity may promote osteoclast activity and bone - resorption through modifying the receptor activator of NF-κB (RANK)/RANK - ligand/osteoprotegerin pathway. Furthermore, the excessive secretion of leptin - and/or decreased production of adiponectin by adipocytes in obesity may either - directly affect bone formation or indirectly affect bone resorption through - up-regulated proinflammatory cytokine production. Finally, high-fat intake may - interfere with intestinal calcium absorption and therefore decrease calcium - availability for bone formation. Unraveling the relationship between fat and bone - metabolism at molecular level may help us to develop therapeutic agents to - prevent or treat both obesity and osteoporosis. Obesity, defined as having a body - mass index ≥ 30 kg/m2, is a condition in which excessive body fat accumulates to - a degree that adversely affects health. The rates of obesity rates have doubled - since 1980 and as of 2007, 33% of men and 35% of women in the US are obese. - Obesity is positively associated to many chronic disorders such as hypertension, - dyslipidemia, type 2 diabetes mellitus, coronary heart disease, and certain - cancers. It is estimated that the direct medical cost associated with obesity in - the United States is ~$100 billion per year.Bone mass and strength decrease - during adulthood, especially in women after menopause. These changes can - culminate in osteoporosis, a disease characterized by low bone mass and - microarchitectural deterioration resulting in increased bone fracture risk. It is - estimated that there are about 10 million Americans over the age of 50 who have - osteoporosis while another 34 million people are at risk of developing the - disease. In 2001, osteoporosis alone accounted for some $17 billion in direct - annual healthcare expenditure. Several lines of evidence suggest that obesity and - bone metabolism are interrelated. First, both osteoblasts (bone forming cells) - and adipocytes (energy storing cells) are derived from a common mesenchymal stem - cell and agents inhibiting adipogenesis stimulated osteoblast differentiation and - vice versa, those inhibiting osteoblastogenesis increased adipogenesis. Second, - decreased bone marrow osteoblastogenesis with aging is usually accompanied with - increased marrow adipogenesis. Third, chronic use of steroid hormone, such as - glucocorticoid, results in obesity accompanied by rapid bone loss. Fourth, both - obesity and osteoporosis are associated with elevated oxidative stress and - increased production of proinflammatory cytokines. At present, the mechanisms for - the effects of obesity on bone metabolism are not well defined and will be the - focus of this review. -FAU - Cao, Jay J -AU - Cao JJ -AD - USDA ARS Grand Forks Human Nutrition Research Center, 2420 2nd Ave N, Grand - Forks, ND 58202-9034, USA. Jay.Cao@ars.usda.gov -LA - eng -PT - Journal Article -PT - Review -DEP - 20110615 -PL - England -TA - J Orthop Surg Res -JT - Journal of orthopaedic surgery and research -JID - 101265112 -RN - 0 (Cytokines) -SB - IM -MH - Adipocytes/cytology/physiology -MH - Bone Resorption/physiopathology -MH - Bone and Bones/cytology/*metabolism -MH - Cell Differentiation/physiology -MH - Cytokines/physiology -MH - Humans -MH - Obesity/*metabolism/*physiopathology -MH - Osteoblasts/cytology/physiology -MH - Osteogenesis/physiology -PMC - PMC3141563 -EDAT- 2011/06/17 06:00 -MHDA- 2012/03/02 06:00 -PMCR- 2011/06/15 -CRDT- 2011/06/17 06:00 -PHST- 2010/04/30 00:00 [received] -PHST- 2011/06/15 00:00 [accepted] -PHST- 2011/06/17 06:00 [entrez] -PHST- 2011/06/17 06:00 [pubmed] -PHST- 2012/03/02 06:00 [medline] -PHST- 2011/06/15 00:00 [pmc-release] -AID - 1749-799X-6-30 [pii] -AID - 10.1186/1749-799X-6-30 [doi] -PST - epublish -SO - J Orthop Surg Res. 2011 Jun 15;6:30. doi: 10.1186/1749-799X-6-30. - -PMID- 22747080 -OWN - NLM -STAT- MEDLINE -DCOM- 20121107 -LR - 20190116 -IS - 1549-7852 (Electronic) -IS - 1040-8398 (Linking) -VI - 52 -IP - 10 -DP - 2012 -TI - Dietary roles of non-starch polysaccharides in human nutrition: a review. -PG - 899-935 -LID - 10.1080/10408398.2010.512671 [doi] -AB - Nonstarch polysaccharides (NSPs) occur naturally in many foods. The - physiochemical and biological properties of these compounds correspond to dietary - fiber. Nonstarch polysaccharides show various physiological effects in the small - and large intestine and therefore have important health implications for humans. - The remarkable properties of dietary NSPs are water dispersibility, viscosity - effect, bulk, and fermentibility into short chain fatty acids (SCFAs). These - features may lead to diminished risk of serious diet related diseases which are - major problems in Western countries and are emerging in developing countries with - greater affluence. These conditions include coronary heart disease, colo-rectal - cancer, inflammatory bowel disease, breast cancer, tumor formation, mineral - related abnormalities, and disordered laxation. Insoluble NSPs (cellulose and - hemicellulose) are effective laxatives whereas soluble NSPs (especially - mixed-link β-glucans) lower plasma cholesterol levels and help to normalize blood - glucose and insulin levels, making these kinds of polysaccharides a part of - dietary plans to treat cardiovascular diseases and Type 2 diabetes. Moreover, a - major proportion of dietary NSPs escapes the small intestine nearly intact, and - is fermented into SCFAs by commensal microflora present in the colon and cecum - and promotes normal laxation. Short chain fatty acids have a number of health - promoting effects and are particularly effective in promoting large bowel - function. Certain NSPs through their fermented products may promote the growth of - specific beneficial colonic bacteria which offer a prebiotic effect. Various - modes of action of NSPs as therapeutic agent have been proposed in the present - review. In addition, NSPs based films and coatings for packaging and wrapping are - of commercial interest because they are compatible with several types of food - products. However, much of the physiological and nutritional impact of NSPs and - the mechanism involved is not fully understood and even the recommendation on the - dose of different dietary NSPs intake among different age groups needs to be - studied. -FAU - Kumar, Vikas -AU - Kumar V -AD - Institute for Animal Production in the Tropics and Subtropics, University of - Hohenheim 70599, Stuttgart, Germany. -FAU - Sinha, Amit K -AU - Sinha AK -FAU - Makkar, Harinder P S -AU - Makkar HP -FAU - de Boeck, Gudrun -AU - de Boeck G -FAU - Becker, Klaus -AU - Becker K -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Crit Rev Food Sci Nutr -JT - Critical reviews in food science and nutrition -JID - 8914818 -RN - 0 (Blood Glucose) -RN - 0 (Dietary Fiber) -RN - 0 (Fatty Acids, Volatile) -RN - 0 (Insulin) -RN - 0 (Polysaccharides) -RN - 0 (Prebiotics) -RN - 0 (beta-Glucans) -RN - 9005-25-8 (Starch) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Blood Glucose/analysis -MH - Cardiovascular Diseases/physiopathology/prevention & control -MH - Chemical Phenomena -MH - Cholesterol/blood -MH - Colon/metabolism/microbiology -MH - Diabetes Mellitus, Type 2/physiopathology/prevention & control -MH - Diet -MH - Dietary Fiber/*administration & dosage -MH - Fatty Acids, Volatile/metabolism -MH - Fermentation -MH - Humans -MH - Insulin/blood -MH - Intestine, Large/metabolism/microbiology -MH - Intestine, Small/metabolism/microbiology -MH - Neoplasms/physiopathology/prevention & control -MH - Nutritional Status -MH - Polysaccharides/*administration & dosage/metabolism -MH - Prebiotics -MH - Starch/*administration & dosage -MH - beta-Glucans/*administration & dosage -EDAT- 2012/07/04 06:00 -MHDA- 2012/11/08 06:00 -CRDT- 2012/07/04 06:00 -PHST- 2012/07/04 06:00 [entrez] -PHST- 2012/07/04 06:00 [pubmed] -PHST- 2012/11/08 06:00 [medline] -AID - 10.1080/10408398.2010.512671 [doi] -PST - ppublish -SO - Crit Rev Food Sci Nutr. 2012;52(10):899-935. doi: 10.1080/10408398.2010.512671. - -PMID- 21804285 -OWN - NLM -STAT- MEDLINE -DCOM- 20111209 -LR - 20190606 -IS - 1349-7235 (Electronic) -IS - 0918-2918 (Linking) -VI - 50 -IP - 15 -DP - 2011 -TI - Rare case of Takayasu's arteritis associated with Crohn's disease. -PG - 1581-5 -AB - Takayasu's arteritis (TA) and Crohn's disease (CD) are chronic inflammatory - diseases of uncertain etiology. Although co-existence of these rare diseases is - estimated to occur in 1 in 10 billion individuals, a theoretically unexpected - association has been reported in several patients and it is suggested that those - associations may have been more than an unusual coincidence. Herein, we report a - case of TA associated with clinically inactive CD. A Japanese woman was diagnosed - with colonic CD at the age of 15, developed aortic valve regurgitation at 19, and - then presented with general fatigue, low grade fever, and painful sensations in - her left arm at 25. She was diagnosed with TA based on computed tomography - scanning and magnetic resonance angiography findings, and treatments with - prednisolone and cyclosporine were started. Thereafter, valve replacement and - right coronary artery bypass graft surgery were performed. The possible - pathophysiological mechanism responsible for concurrent existence of TA and CD - may be associated with immune disorders. Early diagnosis of vascular lesions for - patients with inflammatory bowel disease is highly encouraged. -FAU - Kusunoki, Ryusaku -AU - Kusunoki R -AD - Department of Internal Medicine II, Shimane University School of Medicine, Japan. -FAU - Ishihara, Shunji -AU - Ishihara S -FAU - Sato, Mariko -AU - Sato M -FAU - Sumita, Yoshiko -AU - Sumita Y -FAU - Mishima, Yoshiyuki -AU - Mishima Y -FAU - Okada, Mayumi -AU - Okada M -FAU - Tada, Yasumasa -AU - Tada Y -FAU - Oka, Akihiko -AU - Oka A -FAU - Fukuba, Nobuhiko -AU - Fukuba N -FAU - Oshima, Naoki -AU - Oshima N -FAU - Moriyama, Ichiro -AU - Moriyama I -FAU - Yuki, Takafumi -AU - Yuki T -FAU - Sato, Shuichi -AU - Sato S -FAU - Amano, Yuji -AU - Amano Y -FAU - Murakawa, Yohko -AU - Murakawa Y -FAU - Kinoshita, Yoshikazu -AU - Kinoshita Y -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20110801 -PL - Japan -TA - Intern Med -JT - Internal medicine (Tokyo, Japan) -JID - 9204241 -RN - 5Q7ZVV76EI (Warfarin) -RN - 83HN0GTJ6D (Cyclosporine) -RN - 9PHQ9Y1OLM (Prednisolone) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Adolescent -MH - Adult -MH - Aortic Valve Insufficiency/complications/surgery -MH - Aspirin/administration & dosage -MH - Coronary Artery Bypass -MH - Crohn Disease/*complications/diagnosis -MH - Cyclosporine/administration & dosage -MH - Drug Therapy, Combination -MH - Female -MH - Heart Valve Prosthesis Implantation -MH - Humans -MH - Magnetic Resonance Angiography -MH - Prednisolone/administration & dosage -MH - Takayasu Arteritis/*complications/diagnosis/drug therapy/surgery -MH - Tomography, X-Ray Computed -MH - Warfarin/administration & dosage -MH - Young Adult -EDAT- 2011/08/02 06:00 -MHDA- 2011/12/14 06:00 -CRDT- 2011/08/02 06:00 -PHST- 2011/08/02 06:00 [entrez] -PHST- 2011/08/02 06:00 [pubmed] -PHST- 2011/12/14 06:00 [medline] -AID - JST.JSTAGE/internalmedicine/50.5406 [pii] -AID - 10.2169/internalmedicine.50.5406 [doi] -PST - ppublish -SO - Intern Med. 2011;50(15):1581-5. doi: 10.2169/internalmedicine.50.5406. Epub 2011 - Aug 1. - -PMID- 22633296 -OWN - NLM -STAT- MEDLINE -DCOM- 20120920 -LR - 20120528 -IS - 1875-2128 (Electronic) -IS - 1875-2128 (Linking) -VI - 105 -IP - 4 -DP - 2012 Apr -TI - Diabetic cardiomyopathy: myth or reality? -PG - 218-25 -LID - 10.1016/j.acvd.2011.11.007 [doi] -AB - Diabetes mellitus has reached an epidemic level worldwide. Cardiovascular - diseases are the primary cause of death in diabetic patients, not only because of - coronary artery disease and associated hypertension but also because of a direct - adverse effect of diabetes on the heart, independent of other potential - aetiological factors. However, the existence of this 'diabetic cardiomyopathy' - remains controversial. We aimed to review current evidence for the existence of - diabetic cardiomyopathy, focusing particularly on the clinical setting. -CI - Copyright © 2012 Elsevier Masson SAS. All rights reserved. -FAU - Ernande, Laura -AU - Ernande L -AD - Services des explorations fonctionnelles cardiovasculaires, hôpital Louis-Pradel, - 59, boulevard Pinel, 69500 Bron, France. laura.ernande@gmail.com -FAU - Derumeaux, Geneviève -AU - Derumeaux G -LA - eng -PT - Journal Article -PT - Review -DEP - 20120309 -PL - Netherlands -TA - Arch Cardiovasc Dis -JT - Archives of cardiovascular diseases -JID - 101465655 -SB - IM -MH - Animals -MH - *Diabetic Cardiomyopathies/diagnosis/mortality/physiopathology/therapy -MH - Disease Progression -MH - Evidence-Based Medicine -MH - Humans -MH - Prognosis -MH - Risk Assessment -MH - Risk Factors -EDAT- 2012/05/29 06:00 -MHDA- 2012/09/21 06:00 -CRDT- 2012/05/29 06:00 -PHST- 2011/09/20 00:00 [received] -PHST- 2011/11/09 00:00 [revised] -PHST- 2011/11/14 00:00 [accepted] -PHST- 2012/05/29 06:00 [entrez] -PHST- 2012/05/29 06:00 [pubmed] -PHST- 2012/09/21 06:00 [medline] -AID - S1875-2136(12)00021-6 [pii] -AID - 10.1016/j.acvd.2011.11.007 [doi] -PST - ppublish -SO - Arch Cardiovasc Dis. 2012 Apr;105(4):218-25. doi: 10.1016/j.acvd.2011.11.007. - Epub 2012 Mar 9. - -PMID- 16671404 -OWN - NLM -STAT- MEDLINE -DCOM- 20060605 -LR - 20060504 -IS - 1064-3745 (Print) -IS - 1064-3745 (Linking) -VI - 316 -DP - 2006 -TI - Clinical applications of bioinformatics, genomics, and pharmacogenomics. -PG - 159-77 -AB - Elucidation of the entire human genomic sequence is one of the greatest - achievements of science. Understanding the functional role of 30,000 human genes - and more than 2 million polymorphisms was possible through a multidisciplinary - approach using micro-arrays and bioinformatics. Polymorphisms, variations in DNA - sequences, occur in 1% of the population, and a vast majority of them are single - nucleotide polymorphisms. Genotype analysis has identified genes important in - thrombosis, cardiac defects, and risk of cardiac disease. Many of the genes show - a significant correlation with polymorphisms and the incidence of coronary artery - disease and heart failure. In this chapter, the application of current - state-of-the-art genomic analysis to a variety of these disorders is reviewed. -FAU - Iqbal, Omer -AU - Iqbal O -AD - Department of Pathology, Loyola University Medical Center, Maywood, IL, USA. -FAU - Fareed, Jawed -AU - Fareed J -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Methods Mol Biol -JT - Methods in molecular biology (Clifton, N.J.) -JID - 9214969 -SB - IM -MH - Computational Biology/*methods -MH - *Genomics -MH - Humans -MH - *Pharmacogenetics -RF - 108 -EDAT- 2006/05/05 09:00 -MHDA- 2006/06/06 09:00 -CRDT- 2006/05/05 09:00 -PHST- 2006/05/05 09:00 [pubmed] -PHST- 2006/06/06 09:00 [medline] -PHST- 2006/05/05 09:00 [entrez] -AID - 10.1385/1-59259-964-8:159 [doi] -PST - ppublish -SO - Methods Mol Biol. 2006;316:159-77. doi: 10.1385/1-59259-964-8:159. - -PMID- 18312902 -OWN - NLM -STAT- MEDLINE -DCOM- 20080415 -LR - 20131121 -IS - 0733-8651 (Print) -IS - 0733-8651 (Linking) -VI - 26 -IP - 1 -DP - 2008 Feb -TI - Aldosterone blockade in patients with chronic heart failure. -PG - 15-21, v -LID - 10.1016/j.ccl.2007.12.016 [doi] -AB - Aldosterone blockade has been shown to be effective in reducing mortality in - patients who have severe heart failure because of systolic left ventricular - dysfunction (SLVD) and those who have heart failure and SLVD post-myocardial - infarction. Aldosterone blockade also may be beneficial in patients who have New - York Heart Association class II heart failure, asymptomatic left ventricular - dysfunction, and heart failure with preserved or normal left ventricular - function. Considering the beneficial effects of aldosterone blockade on improving - nitric oxide availability, endothelial function, and atherosclerosis, it can also - be postulated that an aldosterone blockade would add to the benefits of an - angiotensin-converting enzyme inhibitor in patients who have coronary artery - disease. However, these hypotheses must be confirmed in well-designed, - large-scale, prospectively randomized studies. -FAU - Pitt, Bertram -AU - Pitt B -AD - University of Michigan School of Medicine, 1500 East Medical Center Drive, Ann - Arbor, MI 48109, USA. bpitt@umich.edu -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -RN - 4964P6T9RB (Aldosterone) -SB - IM -MH - Aldosterone/*metabolism -MH - Heart Failure/*physiopathology -MH - Humans -RF - 48 -EDAT- 2008/03/04 09:00 -MHDA- 2008/04/16 09:00 -CRDT- 2008/03/04 09:00 -PHST- 2008/03/04 09:00 [pubmed] -PHST- 2008/04/16 09:00 [medline] -PHST- 2008/03/04 09:00 [entrez] -AID - S0733-8651(07)00154-3 [pii] -AID - 10.1016/j.ccl.2007.12.016 [doi] -PST - ppublish -SO - Cardiol Clin. 2008 Feb;26(1):15-21, v. doi: 10.1016/j.ccl.2007.12.016. - -PMID- 20935440 -OWN - NLM -STAT- MEDLINE -DCOM- 20110802 -LR - 20121115 -IS - 1016-5169 (Print) -IS - 1016-5169 (Linking) -VI - 38 -IP - 4 -DP - 2010 Jun -TI - [Percutaneous treatment of aortic stenosis]. -PG - 290-301 -AB - Aortic stenosis has emerged as a global pandemic with the ageing population and - has become the third leading cause of structural heart disease after hypertension - and coronary artery disease in industrialized countries. Older age and presence - of serious comorbid conditions make surgery prohibitively risky in a large group - of patients. The long-term results of balloon aortic valvuloplasty have been - unsatisfactory, limiting the use of this procedure to only palliation or as a - bridge to surgery. Percutaneous aortic prosthetic valve implantation has emerged - as a new treatment modality for patients who are not eligible for surgery. After - the first successful human application in 2002, transcatheter aortic valve - implantation has undergone dramatic technologic improvements, yielding highly - promising results. This review presents an outline on the ongoing evolution of - transcatheter aortic valve implantation in an attempt to provide insight into its - future use in the clinical management of severe aortic stenosis. -FAU - Aksu, Tolga -AU - Aksu T -AD - Department of Cardiology, Türkiye Yüksek İhtisas Heart-Education and Research - Hospital, Ankara, Turkey. aksutolga@gmail.com -FAU - Yüksel, Uygar Cağdaş -AU - Yüksel UC -FAU - Tuzcu, Murat -AU - Tuzcu M -LA - tur -PT - English Abstract -PT - Journal Article -PT - Review -TT - Aort darlığının kateter yoluyla tedavisi. -PL - Turkey -TA - Turk Kardiyol Dern Ars -JT - Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir -JID - 9426239 -SB - IM -MH - *Aortic Valve -MH - Aortic Valve Stenosis/*therapy -MH - Catheterization/*methods -MH - *Heart Valve Prosthesis -MH - Heart Valve Prosthesis Implantation/*methods -MH - Humans -EDAT- 2010/10/12 06:00 -MHDA- 2011/08/04 06:00 -CRDT- 2010/10/12 06:00 -PHST- 2010/10/12 06:00 [entrez] -PHST- 2010/10/12 06:00 [pubmed] -PHST- 2011/08/04 06:00 [medline] -PST - ppublish -SO - Turk Kardiyol Dern Ars. 2010 Jun;38(4):290-301. - -PMID- 17978551 -OWN - NLM -STAT- MEDLINE -DCOM- 20071228 -LR - 20190724 -IS - 0031-6903 (Print) -IS - 0031-6903 (Linking) -VI - 127 -IP - 11 -DP - 2007 Nov -TI - [Pharmaceutical support in the cardiovascular and cardiovascular surgery ward]. -PG - 1767-79 -AB - Pharmacological support for the appropriate use of drugs is important. To promote - such support, it is necessary to be involved in drug therapy from viewpoints - different from those of physicians and nurses, using tools unique to pharmacists, - pharmacologically discuss individual cases, and investigate the validity of - prescriptions by accumulating data. In Chapter 1, digoxin is necessary to monitor - therapy very closely. In addition, patients with an impaired renal dysfunction - have a predisposition for developing digitalis toxicity. In clinical cases, - digoxin and verapamil are often co-administered for heart rate control, and we - have observed the serum trough level of beta-methyldigoxin to be elevated due to - drug-interaction. We build upon our previous findings and generated a simple - index for the adequate administration dosage of beta-methyldigoxin based on - variable degrees of renal function and the serum trough level of - beta-methyldigoxin. In Chapter 2, to investigate risk factors of postoperative - infection following cardiac surgery, we conducted a retrospective analysis of two - surgical procedures, off-pump coronary artery bypass grafting (OPCAB) and surgery - for valvular heart disease (valve operation). After discussing the analysis - results with the respective physicians, the dosing guidelines for cefazolin (CEZ) - were changed. We also analyzed the rate of CEZ replacement with other antibiotics - after surgery finding that it decreased in both groups for OPCAB and valve - operations. From these results, we conclude that, if CEZ is also administered - intra-operatively when surgery is prolonged, its administration for two days - following surgery is adequate for prophylaxis against postoperative infection. -FAU - Machida, Seiji -AU - Machida S -AD - Dept. Pharm. Kokura Memorial Hospital, Kifunemachi, Kitakyushu, Japan. - machida-s@kokurakinen.or.jp -FAU - Masuda, Kazuhisa -AU - Masuda K -FAU - Kataoka, Yasufumi -AU - Kataoka Y -LA - jpn -PT - English Abstract -PT - Journal Article -PT - Review -PL - Japan -TA - Yakugaku Zasshi -JT - Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan -JID - 0413613 -RN - 0 (Anti-Bacterial Agents) -RN - 73K4184T59 (Digoxin) -RN - CJ0O37KU29 (Verapamil) -RN - IHS69L0Y4T (Cefazolin) -SB - IM -MH - Aged -MH - Anti-Bacterial Agents/administration & dosage/adverse effects -MH - *Cardiology Service, Hospital -MH - Cefazolin/administration & dosage/adverse effects -MH - Coronary Artery Bypass, Off-Pump -MH - Digoxin/administration & dosage/adverse effects -MH - *Drug Information Services -MH - Drug Interactions -MH - Drug Therapy, Combination -MH - Female -MH - Heart Valve Diseases/surgery -MH - Humans -MH - Male -MH - Middle Aged -MH - *Pharmacy Service, Hospital -MH - Risk Factors -MH - Surgical Wound Infection/prevention & control -MH - Verapamil/administration & dosage/adverse effects -RF - 19 -EDAT- 2007/11/06 09:00 -MHDA- 2007/12/29 09:00 -CRDT- 2007/11/06 09:00 -PHST- 2007/11/06 09:00 [pubmed] -PHST- 2007/12/29 09:00 [medline] -PHST- 2007/11/06 09:00 [entrez] -AID - JST.JSTAGE/yakushi/127.1767 [pii] -AID - 10.1248/yakushi.127.1767 [doi] -PST - ppublish -SO - Yakugaku Zasshi. 2007 Nov;127(11):1767-79. doi: 10.1248/yakushi.127.1767. - -PMID- 20642107 -OWN - NLM -STAT- MEDLINE -DCOM- 20100802 -LR - 20151119 -IS - 1426-9686 (Print) -IS - 1426-9686 (Linking) -VI - 28 -IP - 168 -DP - 2010 Jun -TI - [Growth differentiation factor 15--a new marker in heart diseases]. -PG - 470-2 -AB - Growth differentiation factor-15 (GDF-15) is a cytokine with cardioprotective - properties, which inhibits hypertrophy, cardiac remodeling and apoptosis. - Participates in the life and cell death. The concentration of GDF-15 rapidly - increases under the influence of ischemia-reperfusion damage to heart muscle, - oxidative stress, inflammatory cytokines and pressure overload. In patients with - acute coronary syndromes, heart failure and pulmonary embolism provides - independent prognostic information, both short-and long-term. It is potentially a - new marker of risk stratification in patients with heart disease and therapeutic - decision making. -FAU - Olechnicki, Maciej -AU - Olechnicki M -AD - 10 Wojskowy Szpital Kliniczny z Poliklinik. w Bydgoszczy, Klinika Kardiologii, - Oddział Kardiologii Inwazyjnej. -FAU - Kasprzak, Krzysztof -AU - Kasprzak K -FAU - Goch, Aleksander -AU - Goch A -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Czynnik róziancowania wzrostu 15--nowy marker chorób serca. -PL - Poland -TA - Pol Merkur Lekarski -JT - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego -JID - 9705469 -RN - 0 (Biomarkers) -RN - 0 (Growth Differentiation Factor 15) -SB - IM -MH - Biomarkers/metabolism -MH - Growth Differentiation Factor 15/*metabolism -MH - Heart Diseases/diagnosis/*metabolism -MH - Humans -MH - Risk Assessment/methods -RF - 18 -EDAT- 2010/07/21 06:00 -MHDA- 2010/08/03 06:00 -CRDT- 2010/07/21 06:00 -PHST- 2010/07/21 06:00 [entrez] -PHST- 2010/07/21 06:00 [pubmed] -PHST- 2010/08/03 06:00 [medline] -PST - ppublish -SO - Pol Merkur Lekarski. 2010 Jun;28(168):470-2. - -PMID- 20941469 -OWN - NLM -STAT- MEDLINE -DCOM- 20110328 -LR - 20211020 -IS - 1615-6692 (Electronic) -IS - 0340-9937 (Linking) -VI - 35 -IP - 7 -DP - 2010 Oct -TI - [High-dose statin therapy for high-risk patients]. -PG - 497-502 -LID - 10.1007/s00059-010-3381-8 [doi] -AB - Lowering LDL cholesterol (LDL-C) with statins decreases cardiovascular risk; - therefore LDL-C is the primary target in lipid therapy. The amount of risk - reduction is the greater, the lower the LDL-C values achieved by statin therapy - are. Current guidelines therefore require an LDL-C as low as < 70 mg/dl in - patients who are at a very high risk of cardiovascular events. This stringent - treatment goal depending on the baseline LDL-C values typically can only be - obtained with higher doses of potent statins. Randomised trials demonstrate the - efficacy of high-dose therapy with atorvastatin 80 mg/day with regard to the - prevention of cardiovascular events in patients after acute coronary syndromes - (PROVE-IT TIMI 22 trial), in patients with stable coronary artery disease (TNT - trial), and in patients after stroke or TIA (SPARCL trial). Moreover, potent - statin treatment reduces the progression of coronary atherosclerosis (REVERSAL - and ASTEROID trials). Furthermore, large meta-analyses of the efficacy of - high-dose statin therapy confirm its safety; in particular, muscle-related - adverse events are not more frequent than with standard statin doses. It is - recommended that evidence-based statin doses be used in clinical practice; the - dosages used in clinical trials should be given rather than titrating patients to - LDL-C targets by increasing statin doses in a stepwise manner. Whether the strong - LDL-C lowering combination of simvastatin plus ezetimibe will reduce - cardiovascular events over and above simvastatin monotherapy is currently being - tested in the ongoing IMPROVE-IT trial. Importantly, despite the large body of - evidence in favour of high-dose statin therapy for patients at high - cardiovascular risk, high-dose statin therapy is still underused and LDL-C goals - are still not met in the majority of these patients. -FAU - Saely, C H -AU - Saely CH -AD - Abteilung für Innere Medizin und Kardiologie und VIVIT-Institut, Akademisches - Lehrkrankenhaus Feldkirch, Carinagasse 47, 6807, Feldkirch, Österreich. - vivit@lkhf.at -FAU - Drexel, H -AU - Drexel H -FAU - Huber, K -AU - Huber K -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Hochdosierte Statintherapie für kardiovaskuläre Risikopatienten. -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - *Evidence-Based Medicine -MH - Heart Diseases/*mortality/*prevention & control -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage -MH - Incidence -MH - Risk Assessment -MH - Risk Factors -MH - Survival Rate -EDAT- 2010/10/14 06:00 -MHDA- 2011/03/29 06:00 -CRDT- 2010/10/14 06:00 -PHST- 2010/10/14 06:00 [entrez] -PHST- 2010/10/14 06:00 [pubmed] -PHST- 2011/03/29 06:00 [medline] -AID - 10.1007/s00059-010-3381-8 [doi] -PST - ppublish -SO - Herz. 2010 Oct;35(7):497-502. doi: 10.1007/s00059-010-3381-8. - -PMID- 24188215 -OWN - NLM -STAT- MEDLINE -DCOM- 20140527 -LR - 20181202 -IS - 1558-2264 (Electronic) -IS - 0733-8651 (Linking) -VI - 31 -IP - 4 -DP - 2013 Nov -TI - From the coronary care unit to the cardiovascular intensive care unit: the - evolution of cardiac critical care. -PG - 485-92, vii -LID - S0733-8651(13)00075-1 [pii] -LID - 10.1016/j.ccl.2013.07.012 [doi] -AB - This article presents an overview of the evolution of cardiac critical care in - the past half century. It tracks the rapid advances in the management of - cardiovascular disease and how the intensive care area has kept pace, improving - outcomes and incorporating successive innovations. The current multidisciplinary, - evidence based unit is vastly different from the early days and is expected to - evolve further in keeping with the concept of 'hybrid' care areas where care is - delivered by the 'heart team'. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Gidwani, Umesh K -AU - Gidwani UK -AD - The Zena and Michael A. Wiener Cardiovascular Institute, The Icahn School of - Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA. - Electronic address: umesh.gidwani@mountsinai.org. -FAU - Kini, Annapoorna S -AU - Kini AS -LA - eng -PT - Journal Article -PT - Review -DEP - 20130920 -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -SB - IM -MH - Arrhythmias, Cardiac/therapy -MH - Clinical Competence -MH - Coronary Care Units/*trends -MH - Critical Care/*trends -MH - Cross Infection/prevention & control -MH - Evidence-Based Medicine/trends -MH - Health Resources/statistics & numerical data/trends -MH - Humans -MH - Intensive Care Units/*trends -MH - Medical Errors/prevention & control -MH - Medical Staff, Hospital/organization & administration/trends -MH - Myocardial Infarction/*therapy -MH - Patient Care Team/organization & administration/trends -MH - Patient Safety -MH - Personnel Staffing and Scheduling/organization & administration -MH - Quality of Health Care -MH - Thrombolytic Therapy/trends -OTO - NOTNLM -OT - Cardiac critical care -OT - Cardiovascular intensive care -OT - Multidisciplinary heart care -EDAT- 2013/11/06 06:00 -MHDA- 2014/05/28 06:00 -CRDT- 2013/11/06 06:00 -PHST- 2013/11/06 06:00 [entrez] -PHST- 2013/11/06 06:00 [pubmed] -PHST- 2014/05/28 06:00 [medline] -AID - S0733-8651(13)00075-1 [pii] -AID - 10.1016/j.ccl.2013.07.012 [doi] -PST - ppublish -SO - Cardiol Clin. 2013 Nov;31(4):485-92, vii. doi: 10.1016/j.ccl.2013.07.012. Epub - 2013 Sep 20. - -PMID- 17505643 -OWN - NLM -STAT- MEDLINE -DCOM- 20080722 -LR - 20190917 -IS - 0004-2730 (Print) -IS - 0004-2730 (Linking) -VI - 51 -IP - 2 -DP - 2007 Mar -TI - [Adjuvant drug treatment in diabetic patients undergoing percutaneous coronary - intervention]. -PG - 334-44 -AB - The authors describe the adjuvant drug treatment during and after percutaneous - coronary intervention in order to obtain the reduction of major cardiovascular - events, focusing in diabetic patients. In the clinical follow-up of diabetic - patients after PCI, special attention to the control measures of cardiovascular - risk factors should be observed. Among those measures, a normal glycemic level is - fundamental, which can be achieved with usual clinical care. Antiplatelet therapy - is a controversy issue until know. Although combined antiplatelet therapy with - aspirin and a thienopyridynic is well supported by a number of clinical trials, - adding GPIIb/IIIa agents as adjuvants in diabetic patients should not be - irrestrictive as suggested by some authors; they should be restricted to patients - with a significative thrombotic burden. -FAU - Lima Filho, Moysés de Oliveira -AU - Lima Filho Mde O -AD - Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, USP, São - Paulo, and Laboratório de Hemodinâmica e Cardiologia Intervencionista, Hospital e - Maternidade Celso Pierro-PUC, Campinas, SP, Brazil. -FAU - Figueiredo, Geraldo Luiz de -AU - Figueiredo GL -FAU - Haddad, Jorge Luis -AU - Haddad JL -FAU - Schmidt, André -AU - Schmidt A -FAU - Lima, Nereida Kilza da Costa -AU - Lima NK -LA - por -PT - English Abstract -PT - Journal Article -PT - Review -TT - Tratamento clínico adjuvante no paciente diabético submetido à intervenção - coronariana percutânea. -PL - Brazil -TA - Arq Bras Endocrinol Metabol -JT - Arquivos brasileiros de endocrinologia e metabologia -JID - 0403437 -RN - 0 (Blood Glucose) -RN - 0 (Hypoglycemic Agents) -RN - 0 (Insulin) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Platelet Glycoprotein GPIIb-IIIa Complex) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - *Angioplasty, Balloon, Coronary/adverse effects -MH - Aspirin/therapeutic use -MH - Blood Glucose/drug effects/metabolism -MH - Cardiovascular Diseases/prevention & control/*therapy -MH - Chemotherapy, Adjuvant -MH - Combined Modality Therapy -MH - Coronary Restenosis/*etiology/prevention & control -MH - Coronary Vessels/injuries -MH - *Diabetes Complications/prevention & control -MH - Humans -MH - Hypoglycemic Agents/administration & dosage -MH - Insulin/administration & dosage -MH - Platelet Aggregation Inhibitors/administration & dosage -MH - Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors -MH - Risk Factors -MH - *Stents -RF - 54 -EDAT- 2007/05/17 09:00 -MHDA- 2008/07/23 09:00 -CRDT- 2007/05/17 09:00 -PHST- 2006/12/31 00:00 [received] -PHST- 2007/01/05 00:00 [accepted] -PHST- 2007/05/17 09:00 [pubmed] -PHST- 2008/07/23 09:00 [medline] -PHST- 2007/05/17 09:00 [entrez] -AID - S0004-27302007000200025 [pii] -AID - 10.1590/s0004-27302007000200025 [doi] -PST - ppublish -SO - Arq Bras Endocrinol Metabol. 2007 Mar;51(2):334-44. doi: - 10.1590/s0004-27302007000200025. - -PMID- 18812323 -OWN - NLM -STAT- MEDLINE -DCOM- 20090108 -LR - 20121115 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 29 -IP - 24 -DP - 2008 Dec -TI - Role of adjunctive thrombectomy and embolic protection devices in acute - myocardial infarction: a comprehensive meta-analysis of randomized trials. -PG - 2989-3001 -LID - 10.1093/eurheartj/ehn421 [doi] -AB - AIMS: Adjunctive thrombectomy and embolic protection devices in acute myocardial - infarction have been extensively studied, although outcomes have mainly focused - on surrogate markers of reperfusion. Therefore, the effect of adjunctive devices - on clinical outcomes is unknown. This study sought to determine whether the use - of a thrombectomy or embolic protection device during revascularization for acute - myocardial infarction reduces mortality compared with percutaneous coronary - intervention (PCI) alone. METHODS AND RESULTS: The Cochrane and Medline databases - were searched for clinical trials that randomized patients with ST-elevation - acute myocardial infarction to an adjuvant device prior to PCI compared with PCI - alone. Devices were grouped into catheter thrombus aspiration, mechanical - thrombectomy, and embolic protection. There were a total of 30 studies with 6415 - patients who met our selection criteria. Over a weighted mean follow-up of 5.0 - months, the incidence of mortality among all studies was 3.2% for the adjunctive - device group vs. 3.7% for PCI alone (relative risk, 0.87; 95% confidence - interval, 0.67-1.13). Among thrombus aspiration studies, mortality was 2.7% for - the adjunctive device group vs. 4.4% for PCI alone (P = 0.018), for mechanical - thrombectomy, mortality was 5.3% for the adjunctive device group vs. 2.8% for PCI - alone (P = 0.050), and for embolic protection, mortality was 3.1% for the - adjunctive device group vs. 3.4% for PCI alone (P = 0.69). CONCLUSION: Catheter - thrombus aspiration during acute myocardial infarction is beneficial in reducing - mortality compared with PCI alone. Mechanical thrombectomy appears to increase - mortality, whereas embolic protection appears to have a neutral effect. -FAU - Bavry, Anthony A -AU - Bavry AA -AD - Department of Cardiovascular Medicine, University of Florida, Gainesville, FL, - USA. -FAU - Kumbhani, Dharam J -AU - Kumbhani DJ -FAU - Bhatt, Deepak L -AU - Bhatt DL -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Meta-Analysis -PT - Review -DEP - 20080923 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -SB - IM -CIN - Eur Heart J. 2008 Dec;29(24):2953-4. doi: 10.1093/eurheartj/ehn488. PMID: - 18952611 -MH - Angioplasty, Balloon, Coronary/*methods/mortality -MH - Cardiac Catheterization/methods -MH - Coronary Angiography -MH - Coronary Thrombosis/mortality/*prevention & control -MH - Embolization, Therapeutic/*methods/mortality -MH - Endpoint Determination -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/mortality/*therapy -MH - Myocardial Reperfusion/methods -MH - Randomized Controlled Trials as Topic -MH - Survival Analysis -MH - Thrombectomy/*methods/mortality -RF - 50 -EDAT- 2008/09/25 09:00 -MHDA- 2009/01/09 09:00 -CRDT- 2008/09/25 09:00 -PHST- 2008/09/25 09:00 [entrez] -PHST- 2008/09/25 09:00 [pubmed] -PHST- 2009/01/09 09:00 [medline] -AID - ehn421 [pii] -AID - 10.1093/eurheartj/ehn421 [doi] -PST - ppublish -SO - Eur Heart J. 2008 Dec;29(24):2989-3001. doi: 10.1093/eurheartj/ehn421. Epub 2008 - Sep 23. - -PMID- 22323896 -OWN - NLM -STAT- MEDLINE -DCOM- 20120606 -LR - 20211021 -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Print) -IS - 1176-6344 (Linking) -VI - 8 -DP - 2012 -TI - New oral antithrombotics: focus on dabigatran, an oral, reversible direct - thrombin inhibitor for the prevention and treatment of venous and arterial - thromboembolic disorders. -PG - 45-57 -LID - 10.2147/VHRM.S26482 [doi] -AB - Venous thromboembolism, presenting as deep vein thrombosis or pulmonary embolism, - is a major challenge for health care systems. It is the third most common - vascular disease after coronary heart disease and stroke, and many hospitalized - patients have at least one risk factor. In particular, patients undergoing hip or - knee replacement are at risk, with an incidence of asymptomatic deep vein - thrombosis of 40%-60% without thromboprophylaxis. Venous thromboembolism is - associated with significant mortality and morbidity, with patients being at risk - of recurrence, post-thrombotic syndrome, and chronic thromboembolic pulmonary - hypertension. Arterial thromboembolism is even more frequent, and atrial - fibrillation, the most common embolic source (cardiac arrhythmia), is associated - with a five-fold increase in the risk of stroke. Strokes due to atrial - fibrillation tend to be more severe and disabling and are more often fatal than - strokes due to other causes. Currently, recommended management of both venous and - arterial thromboembolism involves the use of anticoagulants such as coumarin and - heparin derivatives. These agents are effective, although have characteristics - that prevent them from providing optimal anticoagulation and convenience. Hence, - new improved oral anticoagulants are being investigated. Dabigatran is a - reversible, direct thrombin inhibitor, which is administered as dabigatran - etexilate, the oral prodrug. Because it is the first new oral anticoagulant that - has been licensed in many countries worldwide for thromboprophylaxis following - orthopedic surgery and for stroke prevention in patients with atrial - fibrillation, this compound will be the main focus of this review. Dabigatran has - been investigated for the treatment of established venous thromboembolism and - prevention of recurrence in patients undergoing hip or knee replacement, as well - as for stroke prevention in atrial fibrillation patients with a moderate and high - risk of stroke. -FAU - Dahl, Ola E -AU - Dahl OE -AD - Department of Orthopaedics, Innlandet Hospital Trust, Elverum Central Hospital, - Elverum, Norway. oladahl@start.no -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120125 -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -RN - 0 (Antithrombins) -RN - 0 (Benzimidazoles) -RN - 0 (Fibrinolytic Agents) -RN - 11P2JDE17B (beta-Alanine) -RN - I0VM4M70GC (Dabigatran) -SB - IM -MH - Administration, Oral -MH - Animals -MH - Antithrombins/*administration & dosage/adverse effects -MH - Arterial Occlusive Diseases/blood/*drug therapy/etiology/prevention & control -MH - Benzimidazoles/*administration & dosage/adverse effects -MH - Blood Coagulation/*drug effects -MH - Dabigatran -MH - Fibrinolytic Agents/*administration & dosage/adverse effects -MH - Humans -MH - Risk Factors -MH - Thromboembolism/blood/*drug therapy/etiology/prevention & control -MH - Treatment Outcome -MH - Venous Thromboembolism/blood/*drug therapy/etiology/prevention & control -MH - beta-Alanine/administration & dosage/adverse effects/*analogs & derivatives -PMC - PMC3273411 -OTO - NOTNLM -OT - dabigatran etexilate -OT - prevention -OT - stroke -OT - treatment -OT - venous thromboembolism -EDAT- 2012/02/11 06:00 -MHDA- 2012/06/07 06:00 -PMCR- 2012/01/25 -CRDT- 2012/02/11 06:00 -PHST- 2012/02/11 06:00 [entrez] -PHST- 2012/02/11 06:00 [pubmed] -PHST- 2012/06/07 06:00 [medline] -PHST- 2012/01/25 00:00 [pmc-release] -AID - vhrm-8-045 [pii] -AID - 10.2147/VHRM.S26482 [doi] -PST - ppublish -SO - Vasc Health Risk Manag. 2012;8:45-57. doi: 10.2147/VHRM.S26482. Epub 2012 Jan 25. - -PMID- 19098298 -OWN - NLM -STAT- MEDLINE -DCOM- 20090611 -LR - 20220309 -IS - 1755-3245 (Electronic) -IS - 0008-6363 (Linking) -VI - 81 -IP - 4 -DP - 2009 Mar 1 -TI - Does reversal of oxidative stress and inflammation provide vascular protection? -PG - 649-59 -LID - 10.1093/cvr/cvn354 [doi] -AB - Chronic inflammation is a pathogenic feature of atherosclerosis and - cardiovascular disease mediated by substances including angiotensin II, - proinflammatory cytokines, and free fatty acids. This promotes generation of - reactive oxygen species in vascular endothelial cells and smooth muscle cells, - which mediate injury through several mechanisms. Reciprocal relationships between - endothelial dysfunction and insulin resistance as well as cross-talk between - hyperlipidaemia and the renin-angiotensin-aldosterone system (RAAS) at multiple - levels contribute importantly to a variety of risk factors. Therefore, - combination therapy that simultaneously addresses multiple mechanisms for the - pathogenesis of atherosclerosis is an attractive emerging concept for slowing - progression of atherosclerosis. Combined therapy with statins, peroxisome - proliferator-activated receptors, and RAAS blockade demonstrates additive - beneficial effects on endothelial dysfunction and insulin resistance when - compared with monotherapies in patients with cardiovascular risk factors due to - both distinct and interrelated mechanisms. These additive beneficial effects of - combined therapies are consistent with laboratory and recent clinical studies. - Thus, combination therapy may be an important paradigm for treating and slowing - progression of atherosclerosis, coronary heart disease, and co-morbid metabolic - disorders characterized by endothelial dysfunction and insulin resistance. -FAU - Koh, Kwang Kon -AU - Koh KK -AD - Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gachon - University, Gil Medical Center, 1198 Kuwol-dong, Namdong-gu, Incheon 405-760, - South Korea. kwangk@gilhospital.com -FAU - Oh, Pyung Chun -AU - Oh PC -FAU - Quon, Michael J -AU - Quon MJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20081220 -PL - England -TA - Cardiovasc Res -JT - Cardiovascular research -JID - 0077427 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Antioxidants) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Cardiovascular Agents) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Peroxisome Proliferator-Activated Receptors) -RN - 0 (Reactive Oxygen Species) -RN - 1406-18-4 (Vitamin E) -RN - EC 1.6.3.- (NADPH Oxidases) -RN - PQ6CK8PD0R (Ascorbic Acid) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Animals -MH - Anti-Inflammatory Agents/*therapeutic use -MH - Antioxidants/*therapeutic use -MH - Ascorbic Acid/therapeutic use -MH - Atherosclerosis/*drug therapy/metabolism/physiopathology -MH - Calcium Channel Blockers/therapeutic use -MH - Cardiovascular Agents/*therapeutic use -MH - Drug Therapy, Combination -MH - Endothelium, Vascular/drug effects/metabolism -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Inflammation/*drug therapy/metabolism/physiopathology -MH - Insulin Resistance -MH - NADPH Oxidases/metabolism -MH - Oxidative Stress/*drug effects -MH - Peroxisome Proliferator-Activated Receptors/drug effects -MH - Reactive Oxygen Species/metabolism -MH - Renin-Angiotensin System/drug effects -MH - Treatment Outcome -MH - Vitamin E/therapeutic use -RF - 118 -EDAT- 2008/12/23 09:00 -MHDA- 2009/06/12 09:00 -CRDT- 2008/12/23 09:00 -PHST- 2008/12/23 09:00 [entrez] -PHST- 2008/12/23 09:00 [pubmed] -PHST- 2009/06/12 09:00 [medline] -AID - cvn354 [pii] -AID - 10.1093/cvr/cvn354 [doi] -PST - ppublish -SO - Cardiovasc Res. 2009 Mar 1;81(4):649-59. doi: 10.1093/cvr/cvn354. Epub 2008 Dec - 20. - -PMID- 20829618 -OWN - NLM -STAT- MEDLINE -DCOM- 20101228 -LR - 20100910 -IS - 1423-0194 (Electronic) -IS - 0028-3835 (Linking) -VI - 92 Suppl 1 -DP - 2010 -TI - Cardiovascular disease in Cushing's syndrome: heart versus vasculature. -PG - 50-4 -LID - 10.1159/000318566 [doi] -AB - Cushing's syndrome (CS) causes metabolic abnormalities that determine an - increased cardiovascular risk not only during the active phase of the disease but - also for a long time after cure. Cardiovascular complications, such as premature - atherosclerosis, coronary artery disease, heart failure, and stroke, in patients - with CS cause a mortality rate higher than that observed in a normal population. - The increased cardiovascular risk is mainly due to metabolic complications, such - as metabolic syndrome, but also to vascular and cardiac alterations such as - atherosclerosis and cardiac structural and functional changes. In the clinical - management of patients with CS the focus should be on identifying the global - cardiovascular risk and the aim should be to control not only hypertension but - also other correlated risk factors, such as obesity, glucose intolerance, insulin - resistance, dyslipidemia, endothelial dysfunction and the prothrombotic state. - Considering that remission from hypercortisolism is often difficult to achieve - and that the cardiovascular risk can persist even during disease remission, care - and control of all cardiovascular risk factors should be one of the primary goals - during the follow-up of these patients. -CI - Copyright © 2010 S. Karger AG, Basel. -FAU - De Leo, Monica -AU - De Leo M -AD - Department of Molecular and Clinical Endocrinology and Oncology, Federico II - University of Naples, Naples, Italy. -FAU - Pivonello, Rosario -AU - Pivonello R -FAU - Auriemma, Renata S -AU - Auriemma RS -FAU - Cozzolino, Alessia -AU - Cozzolino A -FAU - Vitale, Pasquale -AU - Vitale P -FAU - Simeoli, Chiara -AU - Simeoli C -FAU - De Martino, Maria Cristina -AU - De Martino MC -FAU - Lombardi, Gaetano -AU - Lombardi G -FAU - Colao, Annamaria -AU - Colao A -LA - eng -PT - Journal Article -PT - Review -DEP - 20100910 -PL - Switzerland -TA - Neuroendocrinology -JT - Neuroendocrinology -JID - 0035665 -SB - IM -MH - Cardiovascular Diseases/*etiology/physiopathology -MH - Cushing Syndrome/*complications/physiopathology -MH - Heart/*physiopathology -MH - Humans -MH - Risk -EDAT- 2010/09/21 06:00 -MHDA- 2010/12/29 06:00 -CRDT- 2010/09/11 06:00 -PHST- 2010/09/11 06:00 [entrez] -PHST- 2010/09/21 06:00 [pubmed] -PHST- 2010/12/29 06:00 [medline] -AID - 000318566 [pii] -AID - 10.1159/000318566 [doi] -PST - ppublish -SO - Neuroendocrinology. 2010;92 Suppl 1:50-4. doi: 10.1159/000318566. Epub 2010 Sep - 10. - -PMID- 20143001 -OWN - NLM -STAT- MEDLINE -DCOM- 20100902 -LR - 20191111 -IS - 0048-7449 (Print) -IS - 0048-7449 (Linking) -VI - 61 -IP - 4 -DP - 2009 Oct-Dec -TI - [Cardiac involvement in rheumatoid arthritis]. -PG - 244-53 -AB - Rheumatoid arthritis (RA) is a systemic disease of unknown etiology characterized - by a chronic inflammatory process mainly leading to destruction of synovial - membrane of small and major diarthrodial joints. The prevalence of RA within the - general adult population is about 1% and female subjects in fertile age result - mostly involved. It's an invalidating disease, associated with changes in life - quality and a reduced life expectancy. Moreover, we can observe an increased - mortality rate in this population early after the onset of the disease. The - mortality excess can be partially due to infective, gastrointestinal, renal or - pulmonary complications and malignancy (mainly lung cancer and non-Hodgkin - lymphoma). Among extra-articular complications, cardiovascular (CV) involvement - represents one of the leading causes of morbidity and mortality. Every cardiac - structure can be affected by different pathogenic pathways: heart valves, - conduction system, myocardium, endocardium, pericardium and coronary arteries. - Consequently, different clinical manifestations can be detected, including: - pericarditis, myocarditis, myocardial fibrosis, arrhythmias, alterations of - conduction system, coronaropathies and ischemic cardiopathy, valvular disease, - pulmonary hypertension and heart failure. Considering that early cardiac - involvement negatively affects the prognosis, it is mandatory to identify high CV - risk RA patients to better define long-term management of this population. -FAU - Turiel, M -AU - Turiel M -AD - Università di Milano, Dipartimento di Tecnologie per la Salute, Milano, Italia. - maurizio.turiel@unimi.it -FAU - Sitia, S -AU - Sitia S -FAU - Tomasoni, L -AU - Tomasoni L -FAU - Cicala, S -AU - Cicala S -FAU - Atzeni, F -AU - Atzeni F -FAU - Gianturco, L -AU - Gianturco L -FAU - Longhi, M -AU - Longhi M -FAU - De Gennaro Colonna, V -AU - De Gennaro Colonna V -FAU - Sarzi-Puttini, P -AU - Sarzi-Puttini P -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - Il coinvolgimento cardiaco nell'artrite reumatoide. -PL - Italy -TA - Reumatismo -JT - Reumatismo -JID - 0401302 -SB - IM -MH - Arthritis, Rheumatoid/*complications -MH - Heart Diseases/*etiology -MH - Humans -RF - 95 -EDAT- 2010/02/10 06:00 -MHDA- 2010/09/03 06:00 -CRDT- 2010/02/10 06:00 -PHST- 2010/02/10 06:00 [entrez] -PHST- 2010/02/10 06:00 [pubmed] -PHST- 2010/09/03 06:00 [medline] -AID - 10.4081/reumatismo.2009.244 [doi] -PST - ppublish -SO - Reumatismo. 2009 Oct-Dec;61(4):244-53. doi: 10.4081/reumatismo.2009.244. - -PMID- 22890066 -OWN - NLM -STAT- MEDLINE -DCOM- 20130204 -LR - 20120907 -IS - 1531-698X (Electronic) -IS - 1040-8703 (Linking) -VI - 24 -IP - 5 -DP - 2012 Oct -TI - The expanding role of the epicardium and epicardial-derived cells in cardiac - development and disease. -PG - 569-76 -LID - 10.1097/MOP.0b013e328357a532 [doi] -AB - PURPOSE OF REVIEW: In this review, we aim at presenting and discussing the - cellular and molecular mechanisms of embryonic epicardial development that may - underlie the origin of congenital heart disease (CHD). RECENT FINDINGS: New - discoveries on the multiple cell lineages that form part of the original pool of - epicardial progenitors and the roles played by epicardial transcription factors - and morphogens in the regulation of epicardial epithelial-to-mesenchymal - transition, epicardial-derived cell (EPDCs) differentiation, coronary blood - vessel morphogenesis and cardiac interstitium formation are presented in a - comprehensive manner. SUMMARY: We have provided evidence on the critical - participation of epicardial cells and EPDCs in normal and abnormal cardiac - development, suggesting the implication of defective epicardial development in - various forms of CHD. -FAU - Ruiz-Villalba, Adrián -AU - Ruiz-Villalba A -AD - Department of Animal Biology, Faculty of Science, University of Málaga, Málaga, - Spain. -FAU - Pérez-Pomares, José M -AU - Pérez-Pomares JM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Opin Pediatr -JT - Current opinion in pediatrics -JID - 9000850 -SB - IM -MH - Animals -MH - Cell Differentiation -MH - *Epithelial-Mesenchymal Transition -MH - Heart Defects, Congenital/embryology/*metabolism -MH - Humans -MH - Myocardium/cytology -MH - Pericardium/*cytology/embryology -MH - Stem Cells/*cytology -EDAT- 2012/08/15 06:00 -MHDA- 2013/02/05 06:00 -CRDT- 2012/08/15 06:00 -PHST- 2012/08/15 06:00 [entrez] -PHST- 2012/08/15 06:00 [pubmed] -PHST- 2013/02/05 06:00 [medline] -AID - 10.1097/MOP.0b013e328357a532 [doi] -PST - ppublish -SO - Curr Opin Pediatr. 2012 Oct;24(5):569-76. doi: 10.1097/MOP.0b013e328357a532. - -PMID- 23771782 -OWN - NLM -STAT- MEDLINE -DCOM- 20140513 -LR - 20211021 -IS - 1525-1497 (Electronic) -IS - 0884-8734 (Print) -IS - 0884-8734 (Linking) -VI - 28 -IP - 10 -DP - 2013 Oct -TI - Stem cell therapy for heart disease. -PG - 1353-63 -LID - 10.1007/s11606-013-2508-z [doi] -AB - Coronary artery disease is the leading cause of death in Americans. After - myocardial infarction, significant ventricular damage persists despite timely - reperfusion and pharmacological management. Treatment is limited, as current - modalities do not cure this damage. In the past decade, stem cell therapy has - emerged as a promising therapeutic solution to restore myocardial function. - Clinical trials have demonstrated safety and beneficial effects in patients - suffering from acute myocardial infarction, heart failure, and dilated - cardiomyopathy. These benefits include improved ventricular function, increased - ejection fraction, and decreased infarct size. Mechanisms of therapy are still - not clearly understood. However, it is believed that paracrine factors, including - stromal cell-derived factor-1, contribute significantly to stem cell benefits. - The purpose of this article is to provide medical professionals with an overview - on stem cell therapy for the heart and to discuss potential future directions. -FAU - Puliafico, Shannon B -AU - Puliafico SB -AD - Northeast Ohio Cardiovascular Specialists (NEOCS), 95 Arch St. Suite 300, Akron, - OH, 44304, USA. -FAU - Penn, Marc S -AU - Penn MS -FAU - Silver, Kevin H -AU - Silver KH -LA - eng -PT - Journal Article -PT - Review -DEP - 20130615 -PL - United States -TA - J Gen Intern Med -JT - Journal of general internal medicine -JID - 8605834 -SB - IM -MH - Clinical Trials as Topic -MH - Graft Survival -MH - Heart Diseases/physiopathology/*therapy -MH - Heart Failure/therapy -MH - Humans -MH - Myocardial Infarction/therapy -MH - Paracrine Communication/physiology -MH - Stem Cell Transplantation/*methods -PMC - PMC3785654 -EDAT- 2013/06/19 06:00 -MHDA- 2014/05/14 06:00 -PMCR- 2014/10/01 -CRDT- 2013/06/18 06:00 -PHST- 2012/12/21 00:00 [received] -PHST- 2013/05/20 00:00 [accepted] -PHST- 2013/03/27 00:00 [revised] -PHST- 2013/06/18 06:00 [entrez] -PHST- 2013/06/19 06:00 [pubmed] -PHST- 2014/05/14 06:00 [medline] -PHST- 2014/10/01 00:00 [pmc-release] -AID - 2508 [pii] -AID - 10.1007/s11606-013-2508-z [doi] -PST - ppublish -SO - J Gen Intern Med. 2013 Oct;28(10):1353-63. doi: 10.1007/s11606-013-2508-z. Epub - 2013 Jun 15. - -PMID- 20625308 -OWN - NLM -STAT- MEDLINE -DCOM- 20110211 -LR - 20151119 -IS - 1558-2035 (Electronic) -IS - 1558-2027 (Linking) -VI - 11 -IP - 12 -DP - 2010 Dec -TI - Cardiological features in idiopathic inflammatory myopathies. -PG - 906-11 -LID - 10.2459/JCM.0b013e32833cdca8 [doi] -AB - Idiopathic inflammatory myopathies (IIMs) represent a heterogeneous group of - autoimmune systemic diseases characterized by chronic muscle weakness and - inflammatory cell infiltrates in skeletal muscle. The most frequent IIMs, such as - adult-onset polymyositis and dermatomyositis, display a wide range of clinical - manifestations other than myositis, including skin changes, Raynaud's phenomenon - and interstitial lung disease. Cardiac involvement is now well recognized as a - clinically important manifestation in patients with polymyositis or - dermatomyositis, although its actual frequency is still uncertain. Cardiovascular - complications represent one of the most frequent causes of death in myositis, - apart from cancer and lung involvement. Despite the fact that clinical - manifestations are relatively rare, asymptomatic cardiovascular features are - frequently reported in patients with polydermatomyositis and dermatomyositis. - They are characterized by isolated electrocardiographic changes, valve disease, - coronary vasculitis, ischemic abnormalities, heart failure and myocarditis. - Chronic inflammation producing myocyte degeneration, tissues fibrosis and - vascular alterations can explain the majority of reported cardiac features in - myositic patients. Although previous works reported an association between heart - involvement and some myositis-specific autoantibodies (namely anti-signal - recognition particle), electrocardiography, echocardiography and, where - necessary, heart magnetic resonance remain the mainstay for diagnosing and - monitoring myocardial inflammation in these diseases. Anyway, a complete - multiorgan assessment and a careful analysis of autoantibodies should be - performed in every patient in order to define any possible distinct disease - entities with different prognosis within the spectrum of IIMs. -FAU - Bazzani, Chiara -AU - Bazzani C -AD - Rheumatology Unit, University of Brescia, Piazzale Spedali Civili, Brescia, - Italy. -FAU - Cavazzana, Ilaria -AU - Cavazzana I -FAU - Ceribelli, Angela -AU - Ceribelli A -FAU - Vizzardi, Enrico -AU - Vizzardi E -FAU - Dei Cas, Livio -AU - Dei Cas L -FAU - Franceschini, Franco -AU - Franceschini F -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Cardiovasc Med (Hagerstown) -JT - Journal of cardiovascular medicine (Hagerstown, Md.) -JID - 101259752 -RN - 0 (Autoantibodies) -RN - 0 (Biomarkers) -SB - IM -MH - Autoantibodies/blood -MH - Biomarkers/blood -MH - Disease Progression -MH - Heart Diseases/diagnosis/*etiology/immunology/physiopathology/therapy -MH - Humans -MH - Myositis/*complications/diagnosis/immunology/physiopathology/therapy -MH - Predictive Value of Tests -MH - Prognosis -EDAT- 2010/07/14 06:00 -MHDA- 2011/02/12 06:00 -CRDT- 2010/07/14 06:00 -PHST- 2010/07/14 06:00 [entrez] -PHST- 2010/07/14 06:00 [pubmed] -PHST- 2011/02/12 06:00 [medline] -AID - 10.2459/JCM.0b013e32833cdca8 [doi] -PST - ppublish -SO - J Cardiovasc Med (Hagerstown). 2010 Dec;11(12):906-11. doi: - 10.2459/JCM.0b013e32833cdca8. - -PMID- 21928176 -OWN - NLM -STAT- MEDLINE -DCOM- 20120126 -LR - 20191112 -IS - 1751-7168 (Electronic) -IS - 1541-9215 (Linking) -VI - 8 -IP - 2 -DP - 2010 Winter -TI - Angina induced by 5-fluorouracil infusion in a patient with normal coronaries. -PG - E111-2 -AB - This article reviews the occurrence of angina in patients treated with - 5-fluorouracil (5-FU) without significant coronary artery disease. We present a - case followed by a review of the literature. A 43-year-old man with a history of - colon cancer developed typical angina during intravenous infusion of 5-FU. His - electrocardiogram (ECG) showed tall T waves during his angina episode. His angina - and ECG changes reoccurred during a second 5-FU infusion. His coronary - angiography was normal. This case is consistent with a rare occurrence of - 5-FU-induced angina despite normal coronaries. Physician should be aware of this - important side effect of 5-FU infusion. -FAU - Tajik, Reza -AU - Tajik R -AD - Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences, - Tehran, Iran. -FAU - Saadat, Habib -AU - Saadat H -FAU - Taherkhani, Maryam -AU - Taherkhani M -FAU - Movahed, Mohammad Reza -AU - Movahed MR -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - England -TA - Am Heart Hosp J -JT - The American heart hospital journal -JID - 101156064 -RN - 0 (Antimetabolites, Antineoplastic) -RN - U3P01618RT (Fluorouracil) -SB - IM -MH - Adult -MH - Angina Pectoris/*chemically induced -MH - Antimetabolites, Antineoplastic/administration & dosage/*adverse effects -MH - Colonic Neoplasms/drug therapy -MH - Coronary Angiography -MH - Coronary Circulation -MH - Electrocardiography -MH - Fluorouracil/administration & dosage/*adverse effects -MH - Humans -MH - Infusions, Intravenous -MH - Male -EDAT- 2010/01/01 00:00 -MHDA- 2012/01/27 06:00 -CRDT- 2011/09/20 06:00 -PHST- 2011/09/20 06:00 [entrez] -PHST- 2010/01/01 00:00 [pubmed] -PHST- 2012/01/27 06:00 [medline] -AID - ahhj.2010.8.2.111 [pii] -AID - 10.15420/ahhj.2010.8.2.111 [doi] -PST - ppublish -SO - Am Heart Hosp J. 2010 Winter;8(2):E111-2. doi: 10.15420/ahhj.2010.8.2.111. - -PMID- 16998516 -OWN - NLM -STAT- MEDLINE -DCOM- 20070625 -LR - 20211203 -IS - 1137-6627 (Print) -IS - 1137-6627 (Linking) -VI - 29 Suppl 2 -DP - 2006 -TI - [Heart transplant]. -PG - 63-78 -AB - A heart transplant is at present considered the treatment of choice in cases of - terminal cardiac insufficiency refractory to medical or surgical treatment. Due - to factors such as the greater life expectancy of the population and the more - efficient management of acute coronary syndromes, there is an increasing number - of people who suffer from heart failure. It is estimated that the prevalence of - the disease in developed countries is around 1%; of this figure, some 10% are in - an advanced stage and are thus potential receptors of a heart transplant. The - problem is that it is still not possible to offer this therapeutic form to all of - the patients that require it. Consequently, it is necessary to optimise the - results of the heart transplant through the selection of patients, selection and - management of donors, perioperative management and control of the disease due to - graft rejection. Since the first transplant carried out in 1967, numerous - advances and changes have taken place, which has made it possible to increase - survival and quality of life of those who have received a new heart. In this - article we review the most relevant aspects of the heart transplant and the - challenges that are currently faced. -FAU - Ubilla, M -AU - Ubilla M -AD - Servicios de Cirugía Cardiovascular y Cardiología, Clínica Universitaria de - Navarra, 31008 Pamplona, Spain. -FAU - Mastrobuoni, S -AU - Mastrobuoni S -FAU - Martín Arnau, A -AU - Martín Arnau A -FAU - Cordero, A -AU - Cordero A -FAU - Alegría, E -AU - Alegría E -FAU - Gavira, J J -AU - Gavira JJ -FAU - Iribarren, M J -AU - Iribarren MJ -FAU - Rodríguez-Fernández, T -AU - Rodríguez-Fernández T -FAU - Herreros, J -AU - Herreros J -FAU - Rábago, G -AU - Rábago G -LA - spa -PT - Comparative Study -PT - Journal Article -PT - Review -TT - Trasplante cardíaco. -PL - Spain -TA - An Sist Sanit Navar -JT - Anales del sistema sanitario de Navarra -JID - 9710381 -SB - IM -MH - Actuarial Analysis -MH - Acute Disease -MH - Adult -MH - Chronic Disease -MH - Female -MH - Follow-Up Studies -MH - Graft Rejection/diagnosis/mortality/therapy -MH - *Heart Transplantation/methods/mortality/statistics & numerical data -MH - Humans -MH - Immunosuppression Therapy -MH - Male -MH - Middle Aged -MH - Patient Selection -MH - Postoperative Care -MH - Postoperative Complications -MH - Practice Guidelines as Topic -MH - Prospective Studies -MH - Randomized Controlled Trials as Topic -MH - *Registries -MH - Time Factors -MH - Tissue Donors -RF - 61 -EDAT- 2006/09/26 09:00 -MHDA- 2007/06/26 09:00 -CRDT- 2006/09/26 09:00 -PHST- 2006/09/26 09:00 [pubmed] -PHST- 2007/06/26 09:00 [medline] -PHST- 2006/09/26 09:00 [entrez] -PST - ppublish -SO - An Sist Sanit Navar. 2006;29 Suppl 2:63-78. - -PMID- 17470338 -OWN - NLM -STAT- MEDLINE -DCOM- 20070619 -LR - 20191110 -IS - 1523-3782 (Print) -IS - 1523-3782 (Linking) -VI - 9 -IP - 3 -DP - 2007 May -TI - Glycemic control and treatment patterns in patients with heart failure. -PG - 242-7 -AB - Patients with diabetes mellitus are more likely to develop heart failure and - cardiac dysfunction (with or without coronary artery disease), and the - combination portends a poorer prognosis. Although the majority of treatment - options in heart failure appear to be as effective in those with diabetes as in - those without, less is known about the safety and effectiveness of different - antidiabetic medications in the setting of heart failure. Nevertheless, it is - well recognized that many patients with diabetes mellitus may develop subclinical - structural heart disease prior to overt clinical presentations. Therefore, the - potential of early detection (or screening) is very important to prevent the - significant disease burden of heart failure in the diabetic population. In-depth - investigations of the role of current and emerging strategies of metabolic - modulation are promising, although the precise therapeutic targets remain - elusive. -FAU - Tang, W H Wilson -AU - Tang WH -AD - Section of Heart Failure and Cardiac Transplantation Medicine, Department of - Cardiovascular Medicine, 9500 Euclid Avenue, Desk F25, Cleveland, OH 44195, USA. - tangw@ccf.org -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -RN - 0 (Blood Glucose) -RN - 0 (Hypoglycemic Agents) -SB - IM -MH - Animals -MH - *Blood Glucose -MH - Diabetes Mellitus, Type 2/blood/complications/*drug therapy -MH - Heart Failure/blood/*complications/drug therapy -MH - Humans -MH - Hypoglycemic Agents/*therapeutic use -MH - Treatment Outcome -RF - 55 -EDAT- 2007/05/02 09:00 -MHDA- 2007/06/20 09:00 -CRDT- 2007/05/02 09:00 -PHST- 2007/05/02 09:00 [pubmed] -PHST- 2007/06/20 09:00 [medline] -PHST- 2007/05/02 09:00 [entrez] -AID - 10.1007/BF02938357 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2007 May;9(3):242-7. doi: 10.1007/BF02938357. - -PMID- 21623288 -OWN - NLM -STAT- MEDLINE -DCOM- 20110927 -LR - 20220311 -IS - 1537-8918 (Electronic) -IS - 1537-890X (Linking) -VI - 10 -IP - 2 -DP - 2011 Mar-Apr -TI - Making prudent recommendations for return-to-play in adult athletes with cardiac - conditions. -PG - 65-77 -LID - 10.1249/JSR.0b013e3182159a55 [doi] -AB - Clinicians who treat millions of adult athletes throughout the world may be faced - with participation or return-to-play decisions in individuals with known or - suspected cardiac conditions. Here we review existing published participation - guidelines and analyze emerging data from ongoing registries and population-based - studies pertaining to return-to-play decisions for cardiac conditions - specifically affecting adult athletes. Considerations related to return-to-play - decisions will vary according to age of the athlete, with inherited disorders - being the main consideration in younger adult athletes aged 18 to 40 yr, and - coronary artery disease being the main consideration in older adult athletes aged - 40 yr and older. Although this arbitrary division is based on the epidemiology of - underlying heart disease in these populations, the essential return-to-play - decision process for both age groups is quite similar. Among the most widely used - guidelines to make return-to-play decisions in this group of athletes are the - 36th Bethesda Conference Eligibility Recommendations for Competitive Athletes - with Cardiovascular Abnormalities. These have long been considered the "gold - standard" for determining return-to-play decisions in young athletes in the - United States. Other guidelines are available for unique purposes, including The - European Society of Cardiology guidelines, and the American Heart Association - published recommendations regarding participation of young patients (younger than - 40 yr) with genetic cardiovascular diseases in recreational sports. The latter - are consistent with the 36th Bethesda guidelines and cover common genetically - based diseases such as inherited cardiomyopathies, channelopathy, and connective - tissue disorders like Marfan's syndrome. The consensus on masters athletes (older - than 40 yr) provides return-to-play decisions for a wide variety of conditioned - states, from elite older athletes to walk-up athletes. For any adult athlete with - a cardiac condition, return-to-play decisions following use of medications, - ablation procedures, device implantation, corrective surgery, or coronary - intervention depend on whether the procedure has sufficiently altered the risk - for sudden cardiac events, and whether there is a potential for unfavorable - interaction with cardiac performance. -FAU - Oliveira, Leonardo P J -AU - Oliveira LP -AD - Cleveland Clinic Sports Health, Department of Orthopaedic Surgery, Cleveland - Clinic, Cleveland, OH, USA. -FAU - Lawless, Christine E -AU - Lawless CE -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Sports Med Rep -JT - Current sports medicine reports -JID - 101134380 -SB - IM -MH - Adult -MH - *Athletes -MH - Death, Sudden, Cardiac/*prevention & control -MH - *Decision Making -MH - Defibrillators, Implantable -MH - Echocardiography, Stress -MH - Exercise -MH - Heart Diseases/*complications/diagnosis/therapy -MH - Humans -MH - Mass Screening -MH - Myocardial Revascularization -MH - Oxygen Consumption -MH - Pacemaker, Artificial -MH - Practice Guidelines as Topic -MH - *Risk Assessment -MH - Sports Medicine -MH - Syncope/etiology -EDAT- 2011/05/31 06:00 -MHDA- 2011/09/29 06:00 -CRDT- 2011/05/31 06:00 -PHST- 2011/05/31 06:00 [entrez] -PHST- 2011/05/31 06:00 [pubmed] -PHST- 2011/09/29 06:00 [medline] -AID - 00149619-201103000-00007 [pii] -AID - 10.1249/JSR.0b013e3182159a55 [doi] -PST - ppublish -SO - Curr Sports Med Rep. 2011 Mar-Apr;10(2):65-77. doi: 10.1249/JSR.0b013e3182159a55. - -PMID- 20641550 -STAT- Publisher -DRDT- 20081219 -CTDT- 20080212 -PB - National Center for Biotechnology Information (US) -DP - 2004 -TI - [(123)I]-β-Methyl iodophenyl-pentadecanoic acid. -BTI - Molecular Imaging and Contrast Agent Database (MICAD) -AB - Under normal conditions the myocardium can metabolize several different types of - substrates for energy. Although fatty acids supply almost 66% of the energy - requirements of this tissue, the myocardium can also metabolize glucose (the - second most preferred substrate), lactate, amino acids, and ketone bodies (1). - Either through β-oxidation or glycolysis the fatty acids and glucose are, - respectively, broken down to acetyl-coenzyme A (CoA), which is further oxidized - through the tricarboxylic acid cycle to produce energy. Certain pathological - conditions, such as ischemia, are known to alter myocardial metabolism, and the - reduced availability of oxygen shifts the myocardium into an anaerobic mode that - leads to an increased utilization of glucose for energy because glycolysis - requires less oxygen in comparison to β-oxidation (2). Therefore, different - imaging agents are used to assess myocardial changes observed during heart - disease. For example, radioactive fluorodeoxyglucose ([(18)F]-FDG) is often used - to evaluate glucose metabolism, labeled acetate is used to assess oxygen - consumption, and fatty acids labeled with iodine ((123)I) are used for - single-photon emission computed tomography (SPECT) of the heart (1). Among the - fatty acids, [(123)I]-β-methyl iodophenyl-pentadecanoic acid ([(123)I]-BMIPP), - used as a racemic mixture ([(125)I]-3(R,S)-BMIPP), is used most frequently for - SPECT imaging of the heart because the methyl group at the β position of the - molecule slows β-oxidation of the fatty acid, which results in prolonged - retention and improved quantitative imaging of the organ (3). Animal and clinical - studies have shown that the CD36 molecule on the cell membrane plays an important - role in the transport of BMIPP into the cell (4). It is then converted to - BMIPP-CoA and rapidly incorporated into triglycerides (5). Using a dual mixture - of [(125)I]-3(R)-BMIPP and [(131)I]-3(S)-BMIPP as surrogate molecules for - [(123)I]-BMIPP to study the effect of BMIPP molecular configuration on its uptake - and metabolism in the rat myocardium, it was shown that uptake of the 3(R)-BMIPP - isomer was higher compared to 3(S)-BMIPP but the two isomers were metabolized in - the same manner in the rat myocardium (6, 7). Morishita et al. proved that BMIPP - was metabolized in the mitochondria of the tissue (8). Other investigators - studying the metabolism of branched-chain fatty acids in the myocardium of rats - with streptozotocin-induced acute or chronic diabetes mellitus concluded that the - uptake of BMIPP was reduced in rats with chronic diabetes mellitus because the - mitochondrial function was not normal in the myocardium of these animals (9). In - humans, [(123)I]-BMIPP was shown to be a superior cardiac SPECT imaging agent - compared to its dimethyl analog, and it has been used extensively for this - purpose in Japan and Europe (1, 7, 10). Akashi et al. investigated the - significance of [(123)I]-BMIPP imaging in cardiac patients and concluded that - this radiochemical enhanced the assessment of fatty acid metabolism disorders in - the myocardium both under normal and diseased conditions (11). Nishimura and - colleagues have shown that [(123)I]-BMIPP scintigraphy can be used to detect - asymptomatic coronary artery disease and predict cardiac death and coronary - artery stenosis in hemodialysis patients (12-14). In the United States, - [(123)I]-BMIPP has been used for the imaging of ischemic heart and coronary - artery disease as well as acute coronary syndrome in clinical trials approved by - the U.S. Food and Drug Administration. The use of [(123)I]-BMIPP for diagnostic - imaging has been patented in the United States (15). -FAU - Chopra, Arvind -AU - Chopra A -AD - National Center for Biotechnology Information, NLM, NIH, Bethesda, MD 20894, - micad@ncbi.nlm.nih.gov -LA - eng -PT - Review -PT - Book Chapter -PL - Bethesda (MD) -OTO - NLM -OT - [123I]-BMIPP -OT - Compound -OT - Myocardial tissue fatty acid metabolism -OT - Uptake -OT - Single-photon emission computed tomography (SPECT) or gamma planar imaging -OT - 123I -EDAT- 2008/12/19 00:00 -CRDT- 2008/12/19 00:00 -AID - NBK23348 [bookaccession] - -PMID- 22283203 -OWN - NLM -STAT- MEDLINE -DCOM- 20120614 -LR - 20161125 -IS - 1540-8175 (Electronic) -IS - 0742-2822 (Linking) -VI - 29 -IP - 2 -DP - 2012 Feb -TI - Real time three-dimensional echocardiography for evaluation of congenital heart - defects: state of the art. -PG - 232-41 -LID - 10.1111/j.1540-8175.2011.01589.x [doi] -AB - Real time three-dimensional echocardiography (RT3DE) has been increasingly used - in the diagnosis and assessment of congenital heart disease. A growing body of - literature suggests that this new technology can be used as an integrated - approach to assess the morphology of simple and complex congenital heart defects, - flow abnormality, and left, right, and single ventricular function both - qualitatively and quantitatively. This review summarizes the available evidence - for the use of RT3DE in each of these areas. Future technology refinement in - RT3DE and development of practice guidelines will increase the utilization of - this new technology as a valuable tool to compliment 2D echocardiography/Doppler - in clinical care and research to improve the care and outcome of congenital heart - disease. -CI - © 2012, Wiley Periodicals, Inc. -FAU - Zhang, Li -AU - Zhang L -AD - Union Hospital, Tongji Medical College of Huazhong University of Science and - Technology, Wuhan, China. -FAU - Xie, Mingxing -AU - Xie M -FAU - Balluz, Rula -AU - Balluz R -FAU - Ge, Shuping -AU - Ge S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Echocardiography -JT - Echocardiography (Mount Kisco, N.Y.) -JID - 8511187 -SB - IM -MH - Blood Flow Velocity -MH - Coronary Circulation -MH - Echocardiography, Doppler/*methods -MH - Echocardiography, Three-Dimensional/*methods -MH - Heart Defects, Congenital/*diagnostic imaging -MH - Humans -EDAT- 2012/01/31 06:00 -MHDA- 2012/06/15 06:00 -CRDT- 2012/01/31 06:00 -PHST- 2012/01/31 06:00 [entrez] -PHST- 2012/01/31 06:00 [pubmed] -PHST- 2012/06/15 06:00 [medline] -AID - 10.1111/j.1540-8175.2011.01589.x [doi] -PST - ppublish -SO - Echocardiography. 2012 Feb;29(2):232-41. doi: 10.1111/j.1540-8175.2011.01589.x. - -PMID- 20446120 -OWN - NLM -STAT- MEDLINE -DCOM- 20110613 -LR - 20211020 -IS - 1534-3170 (Electronic) -IS - 1523-3782 (Linking) -VI - 12 -IP - 4 -DP - 2010 Jul -TI - Acute coronary syndrome in the patient with diabetes: is the management - different? -PG - 321-9 -LID - 10.1007/s11886-010-0118-5 [doi] -AB - Diabetic patients who present with an acute coronary syndrome (ACS) have a - particularly adverse prognosis, largely contributed by increased platelet - reactivity and higher burden of disease severity. Diabetic patients with ACS - derive a greater benefit from established therapies, particularly - platelet-inhibiting therapies, including clopidogrel pretreatment, and - glycoprotein IIb/IIIa inhibitor use. Recent data show intense ADP-P2Y12 platelet - receptor inhibition with prasugrel is of particular clinical value in the - diabetic patient with ACS, without excessive bleeding. Diabetic patients with ACS - also benefit more from aggressive revascularization strategies. Recent data show - the benefit of drug-eluting stents in the setting of primary percutaneous - coronary intervention for ST-segment elevation myocardial infarction in - decreasing target vessel revascularization up to 2 years, particularly in - patients at highest risk for restenosis with bare metal stents (likely diabetic - patients). This review summarizes the data supporting the key pharmacologic and - revascularization management strategies to guide the clinician in taking care of - diabetic patients who present with an ACS event. -FAU - Amin, Amit P -AU - Amin AP -AD - Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO - 64111, USA. -FAU - Marso, Steven P -AU - Marso SP -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -RN - 0 (Anticoagulants) -RN - 0 (Piperazines) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Platelet Glycoprotein GPIIb-IIIa Complex) -RN - 0 (Thiophenes) -RN - A74586SNO7 (Clopidogrel) -RN - G89JQ59I13 (Prasugrel Hydrochloride) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Acute Coronary Syndrome/*drug therapy/mortality/therapy -MH - *Angioplasty, Balloon, Coronary -MH - Anticoagulants/therapeutic use -MH - Clopidogrel -MH - Diabetes Mellitus/physiopathology/*prevention & control -MH - Drug-Eluting Stents -MH - Humans -MH - Piperazines/*therapeutic use -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors -MH - Prasugrel Hydrochloride -MH - Risk Factors -MH - Thiophenes/*therapeutic use -MH - Ticlopidine/*analogs & derivatives/therapeutic use -RF - 48 -EDAT- 2010/05/07 06:00 -MHDA- 2011/06/15 06:00 -CRDT- 2010/05/07 06:00 -PHST- 2010/05/07 06:00 [entrez] -PHST- 2010/05/07 06:00 [pubmed] -PHST- 2011/06/15 06:00 [medline] -AID - 10.1007/s11886-010-0118-5 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2010 Jul;12(4):321-9. doi: 10.1007/s11886-010-0118-5. - -PMID- 24091585 -OWN - NLM -STAT- MEDLINE -DCOM- 20141028 -LR - 20211021 -IS - 1434-9949 (Electronic) -IS - 0770-3198 (Linking) -VI - 33 -IP - 3 -DP - 2014 Mar -TI - Abnormal cardiac enzymes in systemic sclerosis: a report of four patients and - review of the literature. -PG - 435-8 -LID - 10.1007/s10067-013-2405-1 [doi] -AB - Cardiac involvement in systemic sclerosis (SSc) is heterogeneous and can include - primary involvement of the myocardium, pericardium and coronary arteries or be - secondary to cardiac complications of pulmonary and renal disease. Primary - cardiac involvement in SSc is uncommon but can result in ventricular dysfunction, - organ failure, arrhythmias and death. It can remain clinically silent and the - prevalence is likely to be under-reported. We report four cases of SSc associated - with a raised serum troponin T (TnT), in a proportion of whom cardiac MRI - myocardial abnormalities were detected. These cases highlight the heterogeneity - of cardiac involvement in SSc, the role of cardiac MRI and promising biochemical - responses to immunosuppression. Cardiac biomarkers such as TnT may be useful - screening tools to identify subclinical cardiac disease and assess response to - therapeutic intervention. -FAU - Vasta, B -AU - Vasta B -AD - Royal National Hospital for Rheumatic Diseases, Bath, BA1 1RL, UK. -FAU - Flower, V -AU - Flower V -FAU - Bucciarelli-Ducci, C -AU - Bucciarelli-Ducci C -FAU - Brown, S -AU - Brown S -FAU - Korendowych, E -AU - Korendowych E -FAU - McHugh, N J -AU - McHugh NJ -FAU - Pauling, J D -AU - Pauling JD -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20131003 -PL - Germany -TA - Clin Rheumatol -JT - Clinical rheumatology -JID - 8211469 -RN - 0 (Troponin T) -SB - IM -MH - Adult -MH - Aged -MH - Female -MH - Heart/*physiopathology -MH - Heart Diseases/blood/*enzymology/physiopathology -MH - Humans -MH - Male -MH - Middle Aged -MH - Myocardium -MH - Scleroderma, Systemic/blood/*enzymology/physiopathology -MH - Troponin T/*blood -EDAT- 2013/10/05 06:00 -MHDA- 2014/10/29 06:00 -CRDT- 2013/10/05 06:00 -PHST- 2013/08/09 00:00 [received] -PHST- 2013/09/18 00:00 [accepted] -PHST- 2013/10/05 06:00 [entrez] -PHST- 2013/10/05 06:00 [pubmed] -PHST- 2014/10/29 06:00 [medline] -AID - 10.1007/s10067-013-2405-1 [doi] -PST - ppublish -SO - Clin Rheumatol. 2014 Mar;33(3):435-8. doi: 10.1007/s10067-013-2405-1. Epub 2013 - Oct 3. - -PMID- 21452965 -OWN - NLM -STAT- MEDLINE -DCOM- 20110802 -LR - 20161125 -IS - 1557-8682 (Electronic) -IS - 1527-0297 (Linking) -VI - 12 -IP - 1 -DP - 2011 Spring -TI - The effect of altitude-induced hypoxia on heart disease: do acute, intermittent, - and chronic exposures provide cardioprotection? -PG - 45-55 -LID - 10.1089/ham.2010.1021 [doi] -AB - With the global prevalence of heart disease continuing to increase and large - populations living at altitude around the world, we review the concept of - altitude and cardioprotection. Current epidemiologic data, as well as the basic - science and molecular mechanisms involved in acute, intermittent, and chronic - exposure to altitude, are discussed. Intermittent and chronic exposures have been - demonstrated to increase coronary vasculature, decrease infarction size, and - provide more efficient metabolism and better cardiac functional recovery - postischemia. Mechanisms demonstrated in these situations include those mediated - by the hypoxia inducible factor, as well as reactive oxygen species, certain ion - channels, and protein kinases. Although current epidemiologic studies are - difficult to interpret owing to many confounders, many studies point to the - possibility that living at altitude provides cardiovascular protection. Further - research is needed to determine if the bench studies showing mechanisms - consistent with cardioprotection translate to the population living at altitude. -FAU - Anderson, John D -AU - Anderson JD -AD - Department of Emergency Medicine, Denver Health Medical Center, Denver, Colorado, - USA. john.anderson@ucdenver.edu -FAU - Honigman, Benjamin -AU - Honigman B -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - High Alt Med Biol -JT - High altitude medicine & biology -JID - 100901183 -RN - 0 (Hypoxia-Inducible Factor 1) -RN - 0 (Reactive Oxygen Species) -SB - IM -MH - *Altitude -MH - Heart Diseases/metabolism/physiopathology/*prevention & control -MH - Humans -MH - Hypoxia/metabolism/*physiopathology -MH - Hypoxia-Inducible Factor 1/metabolism -MH - Reactive Oxygen Species/metabolism -MH - Risk Factors -MH - Time -EDAT- 2011/04/02 06:00 -MHDA- 2011/08/04 06:00 -CRDT- 2011/04/02 06:00 -PHST- 2011/04/02 06:00 [entrez] -PHST- 2011/04/02 06:00 [pubmed] -PHST- 2011/08/04 06:00 [medline] -AID - 10.1089/ham.2010.1021 [doi] -PST - ppublish -SO - High Alt Med Biol. 2011 Spring;12(1):45-55. doi: 10.1089/ham.2010.1021. - -PMID- 24364273 -OWN - NLM -STAT- MEDLINE -DCOM- 20140206 -LR - 20131224 -IS - 0021-4892 (Print) -IS - 0021-4892 (Linking) -VI - 62 -IP - 11 -DP - 2013 Nov -TI - [Planning of cardiothoracic surgery for chronic kidney disease patients]. -PG - 1320-5 -AB - Chronic renal failure (CRF) is related to cardiac diseases. Cardiac surgery is - also related to postoperative acute kidney injury (AKI). It means heart and - kidney have close relationship. We analyzed recent published data to understand - how to manage CRF patients undergoing cardiovascular surgeries. We compared - endovascular surgery and open procedure for aortic aneurysm, especially about - contrast media-related renal damage, On or Off CABG or PCI for ischemic heart - disease. We also discussed the relation between cardiopulmonary bypass and AKI - and the risk factors causing AKI after CPB. Finally, we discussed prevention and - treatment options of CPB related AKI, including furosemide, hANP mannitol, and - statin. Published evidence in this area is still insufficient, but many studies - are still carried out focusing on postoperative AKI. In the future we may be able - to find the best answer for managing CRF patients undergoing cardiovascular - surgeries. -FAU - Okamoto, Yasuhisa -AU - Okamoto Y -AD - Department of Anesthesiology, IMS Katushika Heart Center, Tokyo 124-0006. -FAU - Nohmi, Tosihiro -AU - Nohmi T -AD - Department of Anesthesiology, IMS Katushika Heart Center, Tokyo 124-0006. -FAU - Seki, Koichiro -AU - Seki K -AD - Department of Anesthesiology, IMS Katushika Heart Center, Tokyo 124-0006. -FAU - Higa, Yuki -AU - Higa Y -AD - Department of Anesthesiology, IMS Katushika Heart Center, Tokyo 124-0006. -LA - jpn -PT - English Abstract -PT - Journal Article -PT - Review -PL - Japan -TA - Masui -JT - Masui. The Japanese journal of anesthesiology -JID - 0413707 -RN - 0 (Contrast Media) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 3OWL53L36A (Mannitol) -RN - 7LXU5N7ZO5 (Furosemide) -RN - 85637-73-6 (Atrial Natriuretic Factor) -SB - IM -MH - Acute Kidney Injury/*prevention & control -MH - Aortic Aneurysm/complications/surgery -MH - Atrial Natriuretic Factor/administration & dosage -MH - Cardiopulmonary Bypass/adverse effects -MH - Cardiovascular Diseases/complications/*surgery -MH - *Cardiovascular Surgical Procedures -MH - Contrast Media/adverse effects -MH - Coronary Artery Bypass -MH - Furosemide/administration & dosage -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage -MH - Mannitol/administration & dosage -MH - Myocardial Ischemia/surgery/therapy -MH - Percutaneous Coronary Intervention -MH - Perioperative Care/*methods -MH - Postoperative Complications/*prevention & control -MH - Renal Insufficiency, Chronic/*complications -MH - *Thoracic Surgical Procedures -EDAT- 2013/12/25 06:00 -MHDA- 2014/02/07 06:00 -CRDT- 2013/12/25 06:00 -PHST- 2013/12/25 06:00 [entrez] -PHST- 2013/12/25 06:00 [pubmed] -PHST- 2014/02/07 06:00 [medline] -PST - ppublish -SO - Masui. 2013 Nov;62(11):1320-5. - -PMID- 16458168 -OWN - NLM -STAT- MEDLINE -DCOM- 20060222 -LR - 20220321 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 47 -IP - 3 Suppl -DP - 2006 Feb 7 -TI - Some thoughts on the vasculopathy of women with ischemic heart disease. -PG - S30-5 -AB - Considerable experimental and clinical data indicate that sex has an important - influence on cardiovascular physiology and pathology. This report integrates - selected literature with new data from the Women's Ischemia Syndrome Evaluation - (WISE) on vascular findings in women with ischemic heart disease (IHD) and how - these findings differ from those in men. A number of common vascular - disease-related conditions are either unique to (e.g., hypertensive disorders of - pregnancy, gestational diabetes, peripartum dissection, polycystic ovarian - syndrome, etc.) or more frequent (e.g., migraine, coronary spasm, lupus, - vasculitis, Raynaud's phenomenon, etc.) in women than men. Post-menopausal women - more frequently have many traditional vascular disease risk conditions (e.g., - hypertension, diabetes, obesity, inactivity, and so on), and these conditions - cluster more frequently in them than men. Considerable evidence supports the - notion that, with these requisite conditions, women develop a more severe or - somewhat different form of vascular disease than men. Structurally, women's - coronary vessels are smaller in size and appear to contain more diffuse - atherosclerosis, their aortas are stiffer (fibrosis, remodeling, and so on), and - their microvessels appear to be more frequently dysfunctional compared with men. - Functionally, women's vessels frequently show impaired vasodilator responses. - Limitations of existing data and higher risks in women with acute myocardial - infarction, need for revascularization, or heart failure create uncertainty about - management. A better understanding of these findings should provide direction for - new algorithms to improve management of the vasculopathy underlying IHD in women. -FAU - Pepine, Carl J -AU - Pepine CJ -AD - Division of Cardiovascular Medicine, Department of Medicine, University of - Florida College of Medicine, Gainesville, Florida, USA. pepincj@medicine.ufl.edu -FAU - Kerensky, Richard A -AU - Kerensky RA -FAU - Lambert, Charles R -AU - Lambert CR -FAU - Smith, Karen M -AU - Smith KM -FAU - von Mering, Gregory O -AU - von Mering GO -FAU - Sopko, George -AU - Sopko G -FAU - Bairey Merz, C Noel -AU - Bairey Merz CN -LA - eng -GR - M01-RR00425/RR/NCRR NIH HHS/United States -GR - N01-HV-68161/HV/NHLBI NIH HHS/United States -GR - N01-HV-68162/HV/NHLBI NIH HHS/United States -GR - N01-HV-68163/HV/NHLBI NIH HHS/United States -GR - N01-HV-68164/HV/NHLBI NIH HHS/United States -GR - U01 HL649141/HL/NHLBI NIH HHS/United States -GR - U01 HL649241/HL/NHLBI NIH HHS/United States -GR - U0164829/PHS HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Cardiovascular System -MH - Endothelium, Vascular/physiology -MH - Female -MH - Humans -MH - Muscle, Smooth, Vascular/physiology -MH - Myocardial Ischemia/*physiopathology -MH - Risk Factors -MH - Sex Factors -RF - 64 -EDAT- 2006/02/07 09:00 -MHDA- 2006/02/24 09:00 -CRDT- 2006/02/07 09:00 -PHST- 2005/09/21 00:00 [received] -PHST- 2005/09/29 00:00 [accepted] -PHST- 2006/02/07 09:00 [pubmed] -PHST- 2006/02/24 09:00 [medline] -PHST- 2006/02/07 09:00 [entrez] -AID - S0735-1097(05)02508-8 [pii] -AID - 10.1016/j.jacc.2005.09.023 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2006 Feb 7;47(3 Suppl):S30-5. doi: 10.1016/j.jacc.2005.09.023. - -PMID- 21180030 -OWN - NLM -STAT- MEDLINE -DCOM- 20110125 -LR - 20161125 -IS - 0019-4832 (Print) -IS - 0019-4832 (Linking) -VI - 62 -IP - 1 -DP - 2010 Jan-Feb -TI - Diagnosis and management of failed thrombolytic therapy for acute myocardial - infarction. -PG - 21-8 -AB - Thrombolytic therapy continues to remain the most frequently adopted treatment - for patients of acute myocardial infarction. Despite our best efforts, - thrombolytic therapy is not uniformly successful. In this review we have - discussed the incidence, diagnosis and management of failed thrombolysis. The - different meta-analysis of rescue angioplasty and various nuances of this - treatment are presented. -FAU - Jariwala, Pankaj -AU - Jariwala P -AD - Department of Cardiology, Nizam's Institute of Medical Sciences, Punjagutta, - Hyderabad, Andhra Pradesh, India. -FAU - Chandra, Sarat -AU - Chandra S -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - India -TA - Indian Heart J -JT - Indian heart journal -JID - 0374675 -RN - 0 (Fibrinolytic Agents) -SB - IM -MH - Acute Disease -MH - Angioplasty, Balloon, Coronary -MH - Clinical Trials as Topic -MH - Electrocardiography -MH - Fibrinolytic Agents/*therapeutic use -MH - Humans -MH - Microcirculation -MH - Myocardial Infarction/diagnosis/diagnostic imaging/*drug - therapy/mortality/therapy -MH - Practice Guidelines as Topic -MH - Radiography -MH - Retrospective Studies -MH - *Thrombolytic Therapy -MH - Treatment Failure -MH - Treatment Outcome -EDAT- 2010/12/25 06:00 -MHDA- 2011/01/28 06:00 -CRDT- 2010/12/25 06:00 -PHST- 2010/12/25 06:00 [entrez] -PHST- 2010/12/25 06:00 [pubmed] -PHST- 2011/01/28 06:00 [medline] -PST - ppublish -SO - Indian Heart J. 2010 Jan-Feb;62(1):21-8. - -PMID- 20608820 -OWN - NLM -STAT- MEDLINE -DCOM- 20101021 -LR - 20131121 -IS - 1744-8298 (Electronic) -IS - 1479-6678 (Linking) -VI - 6 -IP - 4 -DP - 2010 Jul -TI - Epinephrine in resuscitation: curse or cure? -PG - 473-82 -LID - 10.2217/fca.10.24 [doi] -AB - The use of epinephrine during cardiac arrest has been advocated for decades and - forms an integral part of the published guidelines. Its efficacy is supported by - animal data, but human trial evidence is lacking. This is partly attributable to - disparities in trial methodology. Epinephrine's pharmacologic and physiologic - effects include an increase in coronary perfusion pressure that is key to - successful resuscitation. One possible explanation for the lack of epinephrine's - demonstrated efficacy in human trials of out-of-hospital cardiac arrest is the - delay in its administration. A potential solution may be intraosseus epinephrine, - which can be administered quicker. More importantly, it is the quality of the - basic life support, early and uninterrupted chest compressions, early - defibrillation and postresuscitation care that will provide the best chance of - neurologically intact survival. -FAU - Attaran, Robert R -AU - Attaran RR -AD - University of Arizona College of Medicine, Tucson, AZ, USA. -FAU - Ewy, Gordon A -AU - Ewy GA -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Future Cardiol -JT - Future cardiology -JID - 101239345 -RN - 0 (Adrenergic Agonists) -RN - YKH834O4BH (Epinephrine) -SB - IM -MH - Adrenergic Agonists/*administration & dosage -MH - Animals -MH - Cardiopulmonary Resuscitation/*methods/standards -MH - Disease Models, Animal -MH - Dose-Response Relationship, Drug -MH - Epinephrine/*administration & dosage -MH - Heart Arrest/*drug therapy/therapy -MH - Humans -MH - Infusions, Intraosseous -EDAT- 2010/07/09 06:00 -MHDA- 2010/10/22 06:00 -CRDT- 2010/07/09 06:00 -PHST- 2010/07/09 06:00 [entrez] -PHST- 2010/07/09 06:00 [pubmed] -PHST- 2010/10/22 06:00 [medline] -AID - 10.2217/fca.10.24 [doi] -PST - ppublish -SO - Future Cardiol. 2010 Jul;6(4):473-82. doi: 10.2217/fca.10.24. - -PMID- 24035258 -OWN - NLM -STAT- MEDLINE -DCOM- 20140707 -LR - 20171116 -IS - 1768-3181 (Electronic) -IS - 0003-3928 (Linking) -VI - 62 -IP - 5 -DP - 2013 Nov -TI - [Cardiac MRI: technology, clinical applications, and future directions]. -PG - 326-41 -LID - S0003-3928(13)00139-X [pii] -LID - 10.1016/j.ancard.2013.08.010 [doi] -AB - The field of cardiovascular MRI has evolved rapidly over the past decade, feeding - new applications across a broad spectrum of clinical and research areas. Advances - in magnet hardware technology, and key developments such as segmented k-space - acquisitions, advanced motion encoding techniques, ultra-rapid perfusion imaging - and delayed myocardial enhancement imaging have all contributed to a revolution - in how patients with ischemic and non-ischemic heart disease are diagnosed and - treated. Actually, cardiac MRI is a widely accepted method as the "gold standard" - for detection and characterization of many forms of cardiac diseases. The aim of - this review is to present an overview of cardiac MRI technology, advances in - clinical applications, and future directions. -CI - Copyright © 2013 Elsevier Masson SAS. All rights reserved. -FAU - Pesenti-Rossi, D -AU - Pesenti-Rossi D -AD - Services de cardiologie, hôpital de Versailles, 177, rue de Versailles, 78150 Le - Chesnay, France; Clinique Ambroise-Paré, 92200 Neuilly/Seine, France. Electronic - address: david.pesentirossi@gmail.com. -FAU - Peyrou, J -AU - Peyrou J -FAU - Baron, N -AU - Baron N -FAU - Allouch, P -AU - Allouch P -FAU - Aubert, S -AU - Aubert S -FAU - Boueri, Z -AU - Boueri Z -FAU - Livarek, B -AU - Livarek B -LA - fre -PT - Journal Article -PT - Review -TT - IRM cardiaque : technologie actuelle, applications cliniques et perspectives - futures. -DEP - 20130827 -PL - France -TA - Ann Cardiol Angeiol (Paris) -JT - Annales de cardiologie et d'angeiologie -JID - 0142167 -RN - 0 (Contrast Media) -RN - K2I13DR72L (Gadolinium DTPA) -SB - IM -MH - Blood Flow Velocity/physiology -MH - Cardiovascular Diseases/*diagnosis -MH - Contraindications -MH - Contrast Media -MH - Coronary Circulation/physiology -MH - Forecasting -MH - Gadolinium DTPA -MH - Humans -MH - Magnetic Resonance Imaging, Cine/*methods/trends -MH - Myocardium/pathology -MH - Necrosis -MH - Stroke Volume/physiology -OTO - NOTNLM -OT - Cardiac imaging -OT - Cardiac magnetic resonance -OT - Cardiomyopathies non ischémiques -OT - Coronaropathies -OT - Coronary diseases -OT - IRM cardiaque -OT - Imagerie cardiaque -OT - Non ischemic cardiomyopathy -EDAT- 2013/09/17 06:00 -MHDA- 2014/07/08 06:00 -CRDT- 2013/09/17 06:00 -PHST- 2013/07/29 00:00 [received] -PHST- 2013/08/12 00:00 [accepted] -PHST- 2013/09/17 06:00 [entrez] -PHST- 2013/09/17 06:00 [pubmed] -PHST- 2014/07/08 06:00 [medline] -AID - S0003-3928(13)00139-X [pii] -AID - 10.1016/j.ancard.2013.08.010 [doi] -PST - ppublish -SO - Ann Cardiol Angeiol (Paris). 2013 Nov;62(5):326-41. doi: - 10.1016/j.ancard.2013.08.010. Epub 2013 Aug 27. - -PMID- 22950441 -OWN - NLM -STAT- MEDLINE -DCOM- 20130317 -LR - 20181202 -IS - 1744-764X (Electronic) -IS - 1474-0338 (Linking) -VI - 11 -IP - 6 -DP - 2012 Nov -TI - Safety profile and bleeding risk of ticagrelor compared with clopidogrel. -PG - 959-67 -LID - 10.1517/14740338.2012.720972 [doi] -AB - INTRODUCTION: Ticagrelor is a novel, non-thienopyridine ADP inhibitor that - reversibly blocks the P2Y(12) receptor, preventing platelet activation and - aggregation. It is the first ADP inhibitor to show a mortality benefit in - patients with acute coronary syndromes (ACS). Its major safety concern, as with - the other ADP blockers, is bleeding. Other common adverse effects of ticagrelor - such as dyspnea and ventricular pauses appear to be mild and self-limited. AREAS - COVERED: The pharmacological properties of ticagrelor compared with clopidogrel - are explored in this article. In addition, the relevant clinical trials in which - ticagrelor was investigated are described, with an emphasis on efficacy and - safety end points. EXPERT OPINION: Although some patients suffer from dyspnea - when administered with ticagrelor, there is no evidence of any untoward effects - on the cardiovascular or pulmonary systems. Given that the majority of these - episodes are mild to moderate and self-limiting, patients should be encouraged to - continue the medication, as symptoms may resolve. Furthermore, patients with - underlying heart failure or lung disease do not appear to be at an increased risk - of developing ticagrelor-induced dyspnea. Its overall mortality benefit among - patients with ACS, along with its ability to inhibit platelet aggregation more - rapidly and consistently, makes it the preferred agent over clopidogrel. -FAU - May, Christopher H -AU - May CH -AD - Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Avenue/J2-3, - Cleveland, OH 44195, USA. -FAU - Lincoff, A Michael -AU - Lincoff AM -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120905 -PL - England -TA - Expert Opin Drug Saf -JT - Expert opinion on drug safety -JID - 101163027 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Purinergic P2Y Receptor Antagonists) -RN - A74586SNO7 (Clopidogrel) -RN - GLH0314RVC (Ticagrelor) -RN - K72T3FS567 (Adenosine) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Acute Coronary Syndrome/drug therapy/physiopathology -MH - Adenosine/adverse effects/*analogs & derivatives/pharmacology -MH - Clopidogrel -MH - Dyspnea/chemically induced -MH - Hemorrhage/*chemically induced -MH - Humans -MH - Platelet Aggregation Inhibitors/*adverse effects/pharmacology -MH - Purinergic P2Y Receptor Antagonists/adverse effects/pharmacology -MH - Risk Factors -MH - Ticagrelor -MH - Ticlopidine/adverse effects/*analogs & derivatives/pharmacology -EDAT- 2012/09/07 06:00 -MHDA- 2013/03/19 06:00 -CRDT- 2012/09/07 06:00 -PHST- 2012/09/07 06:00 [entrez] -PHST- 2012/09/07 06:00 [pubmed] -PHST- 2013/03/19 06:00 [medline] -AID - 10.1517/14740338.2012.720972 [doi] -PST - ppublish -SO - Expert Opin Drug Saf. 2012 Nov;11(6):959-67. doi: 10.1517/14740338.2012.720972. - Epub 2012 Sep 5. - -PMID- 22281245 -OWN - NLM -STAT- MEDLINE -DCOM- 20120320 -LR - 20220318 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 59 -IP - 5 -DP - 2012 Jan 31 -TI - Silent ischemia: clinical relevance. -PG - 435-41 -LID - 10.1016/j.jacc.2011.07.050 [doi] -AB - Myocardial ischemia can occur without overt symptoms. In fact, asymptomatic (or - silent) ST-segment depression during ambulatory electrocardiogram monitoring - occurs more often than symptomatic ST-segment depression in patients with - coronary artery disease. Initial studies documented that silent ischemia provided - independent prediction of adverse outcomes in patients with known and unknown - coronary artery disease. The ACIP (Asymptomatic Cardiac Ischemia Pilot Study) - enrolled patients in the 1990s and found that revascularization was better than - medical therapy in reducing silent ischemic episodes and possibly cardiovascular - (CV) events. However, the more recent COURAGE (Clinical Outcomes Utilizing - Revascularization and Aggressive Drug Evaluation) trial found similar CV event - rates between patients treated with optimal medical therapy alone and those - treated with optimal medical therapy plus percutaneous revascularization. - Therefore, in the current era, medical therapy appears to be as effective as - revascularization in suppressing symptomatic ischemia and preventing CV events. - COURAGE was not designed to evaluate changes in the frequency of silent ischemia. - Therefore, silent ischemia may persist despite current-era treatment and might - still identify patients with increased risk of CV events. Also, silent ischemia - is likely to occur frequently in heart transplant patients with denervated hearts - and coronary allograft vasculopathy, and future study aimed at improving the - management of silent ischemia in this population is warranted. Additionally, - future research is warranted to study the effect of newer medical therapies such - as ranolazine or selected use of revascularization (for example, guided by - fractional flow reserve) in those patients with persistent silent ischemia - despite optimal current-era medical therapy. -CI - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Conti, C Richard -AU - Conti CR -AD - Department of Medicine, University of Florida College of Medicine, Gainesville, - Florida 32610, USA. -FAU - Bavry, Anthony A -AU - Bavry AA -FAU - Petersen, John W -AU - Petersen JW -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Cardiovascular Agents/*therapeutic use -MH - Diagnosis, Differential -MH - Electrocardiography, Ambulatory/*methods -MH - Exercise Test/*methods -MH - Humans -MH - *Myocardial Ischemia/diagnosis/epidemiology/therapy -MH - Myocardial Revascularization/*methods -EDAT- 2012/01/28 06:00 -MHDA- 2012/03/21 06:00 -CRDT- 2012/01/28 06:00 -PHST- 2011/06/07 00:00 [received] -PHST- 2011/07/11 00:00 [revised] -PHST- 2011/07/18 00:00 [accepted] -PHST- 2012/01/28 06:00 [entrez] -PHST- 2012/01/28 06:00 [pubmed] -PHST- 2012/03/21 06:00 [medline] -AID - S0735-1097(11)03450-4 [pii] -AID - 10.1016/j.jacc.2011.07.050 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2012 Jan 31;59(5):435-41. doi: 10.1016/j.jacc.2011.07.050. - -PMID- 24224132 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140211 -LR - 20241105 -IS - 2160-200X (Print) -IS - 2160-200X (Electronic) -IS - 2160-200X (Linking) -VI - 3 -IP - 4 -DP - 2013 Nov 1 -TI - Mechanisms of load dependency of myocardial ischemia reperfusion injury. -PG - 180-96 -AB - Coronary artery disease and associated ischemic heart disease are prevalent - disorders worldwide. Further, systemic hypertension is common and markedly - increases the risk for heart disease. A common denominator of systemic - hypertension of various etiologies is increased myocardial load/mechanical - stress. Thus, it is likely that high pressure/mechanical stress attenuates the - contribution of cardioprotective but accentuates the contribution of cardiotoxic - pathways thereby exacerbating the outcome of an ischemia reperfusion insult to - the heart. Critical events which contribute to cardiomyocyte injury in the - ischemic-reperfused heart include cellular calcium overload and generation of - reactive oxygen/nitrogen species which, in turn, promote the opening of the - mitochondrial permeability transition pore, an important event in cell death. - Increasing evidence also indicates that the myocardium is capable of mounting a - robust inflammatory response which contributes importantly to tissue injury. On - the other hand, cardioprotective maneuvers of ischemic preconditioning and - postconditioning have led to identification of complex web of signaling pathways - (e.g., reperfusion injury salvage kinase) which ultimately converge on the - mitochondria to exert cytoprotection. The present review is intended to briefly - describe mechanisms of cardiac ischemia reperfusion injury followed by a - discussion of our work focused on how pressure/mechanical stress modulates - endogenous cardiotoxic and cardioprotective mechanisms to ultimately exacerbate - ischemia reperfusion injury. -FAU - Mozaffari, Mahmood S -AU - Mozaffari MS -AD - Department of Oral Biology, College of Dental Medicine, Georgia Regents - University Augusta, Georgia 30912, USA. -FAU - Liu, Jun Yao -AU - Liu JY -FAU - Abebe, Worku -AU - Abebe W -FAU - Baban, Babak -AU - Baban B -LA - eng -PT - Journal Article -PT - Review -DEP - 20131101 -PL - United States -TA - Am J Cardiovasc Dis -JT - American journal of cardiovascular disease -JID - 101569582 -PMC - PMC3819580 -OTO - NOTNLM -OT - Heart -OT - calcium overload -OT - inflammation -OT - ischemia-reperfusion -OT - oxidative/nitrosative stress -OT - pressure -OT - signaling mechanisms -OT - stem cells -EDAT- 2013/11/14 06:00 -MHDA- 2013/11/14 06:01 -PMCR- 2013/11/01 -CRDT- 2013/11/14 06:00 -PHST- 2013/07/26 00:00 [received] -PHST- 2013/10/18 00:00 [accepted] -PHST- 2013/11/14 06:00 [entrez] -PHST- 2013/11/14 06:00 [pubmed] -PHST- 2013/11/14 06:01 [medline] -PHST- 2013/11/01 00:00 [pmc-release] -PST - epublish -SO - Am J Cardiovasc Dis. 2013 Nov 1;3(4):180-96. - -PMID- 22287843 -OWN - NLM -STAT- MEDLINE -DCOM- 20120514 -LR - 20240412 -IS - 1178-2013 (Electronic) -IS - 1176-9114 (Print) -IS - 1176-9114 (Linking) -VI - 7 -DP - 2012 -TI - The role of calcifying nanoparticles in biology and medicine. -PG - 339-50 -LID - 10.2147/IJN.S28069 [doi] -AB - Calcifying nanoparticles (CNPs) (nanobacteria, nanobacteria-like particles, - nanobes) were discovered over 25 years ago; nevertheless, their nature is still - obscure. To date, nobody has been successful in credibly determining whether they - are the smallest self-replicating life form on Earth, or whether they represent - mineralo-protein complexes without any relation to living organisms. Proponents - of both theories have a number of arguments in favor of the validity of their - hypotheses. However, after epistemological analysis carried out in this review, - all arguments used by proponents of the theory about the physicochemical model of - CNP formation may be refuted on the basis of the performed investigations, and - therefore published data suggest a biological nature of CNPs. The only obstacle - to establish CNPs as living organisms is the absence of a fairly accurately - sequenced genome at the present time. Moreover, it is clear that CNPs play an - important role in etiopathogenesis of many diseases, and this association is - independent from their nature. Consequently, emergence of CNPs in an organism is - a pathological, not a physiological, process. The classification and new - directions of further investigations devoted to the role of CNPs in biology and - medicine are proposed. -FAU - Kutikhin, Anton G -AU - Kutikhin AG -AD - Department of Epidemiology, Kemerovo State Medical Academy, Kemerovo, Russian - Federation. antonkutikhin@gmail.com -FAU - Brusina, Elena B -AU - Brusina EB -FAU - Yuzhalin, Arseniy E -AU - Yuzhalin AE -LA - eng -PT - Journal Article -PT - Review -DEP - 20120119 -PL - New Zealand -TA - Int J Nanomedicine -JT - International journal of nanomedicine -JID - 101263847 -RN - 0 (Antibodies) -RN - 0 (Calcifying Nanoparticles) -SB - IM -MH - Animals -MH - Antibodies/immunology -MH - Calcifying Nanoparticles/*adverse - effects/analysis/chemistry/genetics/immunology/*isolation & - purification/metabolism -MH - Calcinosis/*etiology/immunology/microbiology -MH - Coronary Artery Disease/microbiology -MH - Cystitis/microbiology -MH - Humans -MH - Kidney Calculi/chemistry/microbiology -MH - Mitral Valve/microbiology -MH - Models, Chemical -PMC - PMC3266001 -OTO - NOTNLM -OT - diseases -OT - hydroxyapatite -OT - infectious agents -OT - nanobacteria -OT - nanobacteria-like particles -EDAT- 2012/01/31 06:00 -MHDA- 2012/05/15 06:00 -PMCR- 2012/01/19 -CRDT- 2012/01/31 06:00 -PHST- 2012/01/31 06:00 [entrez] -PHST- 2012/01/31 06:00 [pubmed] -PHST- 2012/05/15 06:00 [medline] -PHST- 2012/01/19 00:00 [pmc-release] -AID - ijn-7-339 [pii] -AID - 10.2147/IJN.S28069 [doi] -PST - ppublish -SO - Int J Nanomedicine. 2012;7:339-50. doi: 10.2147/IJN.S28069. Epub 2012 Jan 19. - -PMID- 20635733 -OWN - NLM -STAT- MEDLINE -DCOM- 20100914 -LR - 20100719 -IS - 0019-4832 (Print) -IS - 0019-4832 (Linking) -VI - 61 -IP - 4 -DP - 2009 Jul-Aug -TI - Polypill in cardiovascular disease: has it's time come? -PG - 322-7 -FAU - Kuppuswamy, Velmurugan -AU - Kuppuswamy V -AD - Essex Cardiothoracic Centre, Basildon and Thurrock University Hospital NHS Trust, - Basildon, Essex, UK. -FAU - Choo, Wai Kah -AU - Choo WK -FAU - Gupta, Sandeep -AU - Gupta S -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian Heart J -JT - Indian heart journal -JID - 0374675 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Antihypertensive Agents) -RN - 0 (Drug Combinations) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Acute Coronary Syndrome/drug therapy -MH - Adrenergic beta-Antagonists/administration & dosage -MH - Antihypertensive Agents/administration & dosage -MH - Cardiovascular Diseases/drug therapy/*prevention & control -MH - Developing Countries -MH - Drug Combinations -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage -MH - Patient Compliance -MH - Platelet Aggregation Inhibitors/administration & dosage -MH - Primary Prevention -RF - 28 -EDAT- 2010/07/20 06:00 -MHDA- 2010/09/16 06:00 -CRDT- 2010/07/20 06:00 -PHST- 2010/07/20 06:00 [entrez] -PHST- 2010/07/20 06:00 [pubmed] -PHST- 2010/09/16 06:00 [medline] -PST - ppublish -SO - Indian Heart J. 2009 Jul-Aug;61(4):322-7. - -PMID- 20497611 -OWN - NLM -STAT- MEDLINE -DCOM- 20101110 -LR - 20240322 -IS - 1466-609X (Electronic) -IS - 1364-8535 (Print) -IS - 1364-8535 (Linking) -VI - 14 -IP - 2 -DP - 2010 -TI - Clinical review: practical recommendations on the management of perioperative - heart failure in cardiac surgery. -PG - 201 -LID - 10.1186/cc8153 [doi] -AB - Acute cardiovascular dysfunction occurs perioperatively in more than 20% of - cardiosurgical patients, yet current acute heart failure (HF) classification is - not applicable to this period. Indicators of major perioperative risk include - unstable coronary syndromes, decompensated HF, significant arrhythmias and - valvular disease. Clinical risk factors include history of heart disease, - compensated HF, cerebrovascular disease, presence of diabetes mellitus, renal - insufficiency and high-risk surgery. EuroSCORE reliably predicts perioperative - cardiovascular alteration in patients aged less than 80 years. Preoperative - B-type natriuretic peptide level is an additional risk stratification factor. - Aggressively preserving heart function during cardiosurgery is a major goal. - Volatile anaesthetics and levosimendan seem to be promising cardioprotective - agents, but large trials are still needed to assess the best cardioprotective - agent(s) and optimal protocol(s). The aim of monitoring is early detection and - assessment of mechanisms of perioperative cardiovascular dysfunction. Ideally, - volume status should be assessed by 'dynamic' measurement of haemodynamic - parameters. Assess heart function first by echocardiography, then using a - pulmonary artery catheter (especially in right heart dysfunction). If volaemia - and heart function are in the normal range, cardiovascular dysfunction is very - likely related to vascular dysfunction. In treating myocardial dysfunction, - consider the following options, either alone or in combination: low-to-moderate - doses of dobutamine and epinephrine, milrinone or levosimendan. In - vasoplegia-induced hypotension, use norepinephrine to maintain adequate perfusion - pressure. Exclude hypovolaemia in patients under vasopressors, through repeated - volume assessments. Optimal perioperative use of inotropes/vasopressors in - cardiosurgery remains controversial, and further large multinational studies are - needed. Cardiosurgical perioperative classification of cardiac impairment should - be based on time of occurrence (precardiotomy, failure to wean, postcardiotomy) - and haemodynamic severity of the patient's condition (crash and burn, - deteriorating fast, stable but inotrope dependent). In heart dysfunction with - suspected coronary hypoperfusion, an intra-aortic balloon pump is highly - recommended. A ventricular assist device should be considered before end organ - dysfunction becomes evident. Extra-corporeal membrane oxygenation is an elegant - solution as a bridge to recovery and/or decision making. This paper offers - practical recommendations for management of perioperative HF in cardiosurgery - based on European experts' opinion. It also emphasizes the need for large surveys - and studies to assess the optimal way to manage perioperative HF in cardiac - surgery. -FAU - Mebazaa, Alexandre -AU - Mebazaa A -AD - Department of Anaesthesia and Intensive care, INSERM UMR 942, Lariboisière - Hospital, University of Paris 7 - Diderot, 2 rue Ambroise Paré, Paris, France. - alexandre.mebazaa@lrb.aphp.fr -FAU - Pitsis, Antonis A -AU - Pitsis AA -FAU - Rudiger, Alain -AU - Rudiger A -FAU - Toller, Wolfgang -AU - Toller W -FAU - Longrois, Dan -AU - Longrois D -FAU - Ricksten, Sven-Erik -AU - Ricksten SE -FAU - Bobek, Ilona -AU - Bobek I -FAU - De Hert, Stefan -AU - De Hert S -FAU - Wieselthaler, Georg -AU - Wieselthaler G -FAU - Schirmer, Uwe -AU - Schirmer U -FAU - von Segesser, Ludwig K -AU - von Segesser LK -FAU - Sander, Michael -AU - Sander M -FAU - Poldermans, Don -AU - Poldermans D -FAU - Ranucci, Marco -AU - Ranucci M -FAU - Karpati, Peter C J -AU - Karpati PC -FAU - Wouters, Patrick -AU - Wouters P -FAU - Seeberger, Manfred -AU - Seeberger M -FAU - Schmid, Edith R -AU - Schmid ER -FAU - Weder, Walter -AU - Weder W -FAU - Follath, Ferenc -AU - Follath F -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100428 -PL - England -TA - Crit Care -JT - Critical care (London, England) -JID - 9801902 -SB - IM -MH - *Cardiac Surgical Procedures -MH - Heart Failure/*etiology -MH - Humans -MH - Perioperative Care/*organization & administration -MH - *Practice Guidelines as Topic -MH - Predictive Value of Tests -MH - Prognosis -PMC - PMC2887098 -EDAT- 2010/05/26 06:00 -MHDA- 2010/11/11 06:00 -PMCR- 2011/04/28 -CRDT- 2010/05/26 06:00 -PHST- 2010/05/26 06:00 [entrez] -PHST- 2010/05/26 06:00 [pubmed] -PHST- 2010/11/11 06:00 [medline] -PHST- 2011/04/28 00:00 [pmc-release] -AID - cc8153 [pii] -AID - 10.1186/cc8153 [doi] -PST - ppublish -SO - Crit Care. 2010;14(2):201. doi: 10.1186/cc8153. Epub 2010 Apr 28. - -PMID- 18571250 -OWN - NLM -STAT- MEDLINE -DCOM- 20100923 -LR - 20181201 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 129 -IP - 3 -DP - 2008 Oct 13 -TI - Carcinoid heart disease. -PG - 318-24 -LID - 10.1016/j.ijcard.2008.02.019 [doi] -AB - The carcinoid syndrome is usually evident when enterochromaffin (EC) cell-derived - neuroendocrine tumors (carcinoids) metastasize to the liver. In addition to - carcinoid symptomatology, about 40% of patients exhibit carcinoid heart disease - (CHD) with fibrotic endocardial plaques and associated heart valve dysfunction. - The mechanism behind CHD development is not fully understood, but serotonin - (5-HT) is considered to be a major initiator of the fibrotic process. Most - patients present with right-sided heart valve dysfunction since pulmonary and - tricuspid valves lesions are the most common (>95%) cardiac pathology. Left-sided - valvular involvement, and angina associated with coronary vasospasm occur in ~10% - of subjects with CHD. Pathognomonic echocardiograpic features include immobility - of valve leaflets and thickening and retraction of the cusps most commonly - resulting in tricuspid valve regurgitation and pulmonary stenosis. Therapeutic - options include cardioactive pharmacotherapy for heart failure and, in selected - individuals, cardiac valve replacement. Previously valve replacement was reserved - for advanced disease due to a perioperative mortality of >20% however in the last - decade, technical advances as well as an earlier diagnosis have decreased - surgical mortality to <10% and valve replacements are undertaken more frequently. - A recent analysis of 200 cases demonstrated an increase in median survival from - 1.5 years to 4.4 years in the last two decades. Although the improved prognosis - might also reflect the increased use of surgical cytoreduction, hepatic - metastatic ablative therapies and somatostatin analogs a robust correlation - between diminution of circulating tumor products and an increased long-term - survival in CHD has not been rigorously demonstrated. -FAU - Gustafsson, B I -AU - Gustafsson BI -AD - Department of Gastroenterological Surgery, Yale University School of Medicine New - Haven, CT06520-8062, USA. -FAU - Hauso, O -AU - Hauso O -FAU - Drozdov, I -AU - Drozdov I -FAU - Kidd, M -AU - Kidd M -FAU - Modlin, I M -AU - Modlin IM -LA - eng -PT - Journal Article -PT - Review -DEP - 20080620 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 333DO1RDJY (Serotonin) -RN - 51110-01-1 (Somatostatin) -SB - IM -MH - Animals -MH - Carcinoid Heart Disease/*metabolism/*pathology/therapy -MH - Heart Valve Prosthesis Implantation/statistics & numerical data -MH - Heart Valves/pathology/surgery -MH - Humans -MH - Serotonin/biosynthesis -MH - Somatostatin/therapeutic use -RF - 65 -EDAT- 2008/06/24 09:00 -MHDA- 2010/09/24 06:00 -CRDT- 2008/06/24 09:00 -PHST- 2007/12/05 00:00 [received] -PHST- 2008/02/09 00:00 [accepted] -PHST- 2008/06/24 09:00 [pubmed] -PHST- 2010/09/24 06:00 [medline] -PHST- 2008/06/24 09:00 [entrez] -AID - S0167-5273(08)00436-1 [pii] -AID - 10.1016/j.ijcard.2008.02.019 [doi] -PST - ppublish -SO - Int J Cardiol. 2008 Oct 13;129(3):318-24. doi: 10.1016/j.ijcard.2008.02.019. Epub - 2008 Jun 20. - -PMID- 24328708 -OWN - NLM -STAT- MEDLINE -DCOM- 20140918 -LR - 20240610 -IS - 1744-7682 (Electronic) -IS - 1471-2598 (Print) -IS - 1471-2598 (Linking) -VI - 14 -IP - 2 -DP - 2014 Feb -TI - Cardiovascular gene therapy for myocardial infarction. -PG - 183-95 -LID - 10.1517/14712598.2014.866085 [doi] -AB - INTRODUCTION: Cardiovascular gene therapy is the third most popular application - for gene therapy, representing 8.4% of all gene therapy trials as reported in - 2012 estimates. Gene therapy in cardiovascular disease is aiming to treat heart - failure from ischemic and non-ischemic causes, peripheral artery disease, venous - ulcer, pulmonary hypertension, atherosclerosis and monogenic diseases, such as - Fabry disease. AREAS COVERED: In this review, we will focus on elucidating - current molecular targets for the treatment of ventricular dysfunction following - myocardial infarction (MI). In particular, we will focus on the treatment of i) - the clinical consequences of it, such as heart failure and residual myocardial - ischemia and ii) etiological causes of MI (coronary vessels atherosclerosis, - bypass venous graft disease, in-stent restenosis). EXPERT OPINION: We summarise - the scheme of the review and the molecular targets either already at the gene - therapy clinical trial phase or in the pipeline. These targets will be discussed - below. Following this, we will focus on what we believe are the 4 prerequisites - of success of any gene target therapy: safety, expression, specificity and - efficacy (SESE). -FAU - Scimia, Maria C -AU - Scimia MC -AD - Temple University, Translational Medicine/Pharmacology , 3500 N. Broad Street, - Philadelphia, 19140 , USA walter.koch@Temple.edu. -FAU - Gumpert, Anna M -AU - Gumpert AM -FAU - Koch, Walter J -AU - Koch WJ -LA - eng -GR - F32 HL110675/HL/NHLBI NIH HHS/United States -GR - P01 HL108806/HL/NHLBI NIH HHS/United States -GR - P01 HL075443/HL/NHLBI NIH HHS/United States -GR - R37 HL061690/HL/NHLBI NIH HHS/United States -GR - P01 HL091799/HL/NHLBI NIH HHS/United States -GR - R01 HL085503/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131216 -PL - England -TA - Expert Opin Biol Ther -JT - Expert opinion on biological therapy -JID - 101125414 -RN - 0 (Receptors, Adrenergic) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Animals -MH - Arrhythmias, Cardiac/therapy -MH - Calcium/metabolism -MH - *Cardiovascular System -MH - Gene Expression Profiling -MH - Genetic Therapy/*methods -MH - Humans -MH - Myocardial Infarction/*therapy -MH - Myocardial Ischemia/pathology -MH - Myocardium/pathology -MH - Neovascularization, Physiologic -MH - Receptors, Adrenergic/metabolism -MH - Regeneration -MH - Ventricular Dysfunction/physiopathology/therapy -PMC - PMC4041319 -MID - NIHMS581365 -COIS- Declaration of interest This work is supported by R37 HL061690, R01 HL085503, P01 - HL091799, P01 HL108806, P01 HL075443 and F32 HL110675 to W. J. Koch M. C. Scimia - holds Grants4 Targets from Bayer HealthCare, Drug Discovery Initiative Grant from - Moulder Center of Temple University and the Scientist Development Grant from the - AHA. A. Gumpert holds American Heart Association Postdoctoral Award. -EDAT- 2013/12/18 06:00 -MHDA- 2014/09/19 06:00 -PMCR- 2014/06/02 -CRDT- 2013/12/17 06:00 -PHST- 2013/12/17 06:00 [entrez] -PHST- 2013/12/18 06:00 [pubmed] -PHST- 2014/09/19 06:00 [medline] -PHST- 2014/06/02 00:00 [pmc-release] -AID - 10.1517/14712598.2014.866085 [doi] -PST - ppublish -SO - Expert Opin Biol Ther. 2014 Feb;14(2):183-95. doi: 10.1517/14712598.2014.866085. - Epub 2013 Dec 16. - -PMID- 21150007 -OWN - NLM -STAT- MEDLINE -DCOM- 20110329 -LR - 20240511 -IS - 0971-5916 (Print) -IS - 0971-5916 (Electronic) -IS - 0971-5916 (Linking) -VI - 132 -IP - 5 -DP - 2010 Nov -TI - Congestive heart failure in Indians: how do we improve diagnosis & management? -PG - 549-60 -AB - Heart failure is a common cardiovascular disease with high morbidity and - mortality. Unlike western countries where heart failure is predominantly a - disease of the elderly, in India it affects younger age group. Important risk - factors include coronary artery disease, hypertension, diabetes mellitus, - valvular heart disease and cardiomyopathies. Plasma brain natriuretic peptide - levels are helpful in the diagnosis of heart failure. Echocardiography is the - primary imaging modality of choice, through recently cardiac magnetic resonance - imaging (MRI) has been found to play an increasing role. Aim of management is to - improve symptoms & enhance survival. Diuretics are important in relieving - symptoms. Beta-blockers, angiotensin converting enzyme (ACE) inhibitors, - angiotensin receptor blockers and adosterone antagonists improve survival in - patients with impaired systolic function. Device therapy including cardiac - resynchronization therapy and implantable cardiac defibrillators, though - expensive are useful in selected patients. Unlike in patients with systolic heart - failure where several therapies have been shown to improve survival, clinical - trial results in diastolic heart failure have been disappointing and therapy in - these patients is restricted to symptom improvement and risk factor control. - Therapies like stem cell therapy are being evaluated in clinical trials and - appear promising. Early diagnosis and appropriate therapy helps in reversing the - process of remodelling and clinical improvement in most of the patients. -FAU - Reddy, S -AU - Reddy S -AD - Department of Cardiology, Postgraduate Institute of Medical Education & Research, - Chandigarh, India. -FAU - Bahl, A -AU - Bahl A -FAU - Talwar, K K -AU - Talwar KK -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian J Med Res -JT - The Indian journal of medical research -JID - 0374701 -RN - 0 (Antihypertensive Agents) -RN - 0 (Biomarkers) -RN - 0 (Diuretics) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Antihypertensive Agents/therapeutic use -MH - *Biomarkers -MH - Cardiac Resynchronization Therapy/methods -MH - Defibrillators, Implantable -MH - *Disease Management -MH - Diuretics/therapeutic use -MH - Echocardiography/methods -MH - Electrocardiography/methods -MH - Heart Failure/*diagnosis/*epidemiology/*therapy -MH - Humans -MH - Incidence -MH - India/epidemiology -MH - Magnetic Resonance Imaging/methods -MH - Natriuretic Peptide, Brain/blood -MH - Prevalence -PMC - PMC3028953 -EDAT- 2010/12/15 06:00 -MHDA- 2011/03/30 06:00 -PMCR- 2010/11/01 -CRDT- 2010/12/15 06:00 -PHST- 2010/12/15 06:00 [entrez] -PHST- 2010/12/15 06:00 [pubmed] -PHST- 2011/03/30 06:00 [medline] -PHST- 2010/11/01 00:00 [pmc-release] -AID - IndianJMedRes_2010_132_5_549_73391 [pii] -AID - IJMR-132-549 [pii] -PST - ppublish -SO - Indian J Med Res. 2010 Nov;132(5):549-60. - -PMID- 23589056 -OWN - NLM -STAT- MEDLINE -DCOM- 20140929 -LR - 20211021 -IS - 1436-2813 (Electronic) -IS - 0941-1291 (Linking) -VI - 44 -IP - 3 -DP - 2014 Mar -TI - Minimally invasive aortic valve replacement with orthotopic liver - transplantation: report of a case. -PG - 546-9 -LID - 10.1007/s00595-013-0559-8 [doi] -AB - Cardiac surgery and liver transplantation (LT) are rarely performed at the same - time, because of the potential risks of coupling two such complex surgical - procedures [1-3]. This combined surgery is typically reserved for patients with - structural heart disease, including multivessel obstructive coronary artery - disease and severe valvular disease with heart failure and end-stage liver - disease, in whom the untreated organ may decompensate if only one organ is - addressed [4]. Combined aortic valve replacement (AVR) and LT is the rarest of - such combined surgery, with only ten cases published previously. We present the - first reported case of combined minimally invasive AVR and LT and review the - literature on similar combined surgery. -FAU - Harrison, Jonathan D -AU - Harrison JD -AD - Section of Transplantation and Hepatobiliary Surgery, Department of Surgery, - University of Utah, School of Medicine, 30 North 1900 East, 3B110 SOM, Salt Lake - City, UT, 84132, USA. -FAU - Selzman, Craig H -AU - Selzman CH -FAU - Thiesset, Heather F -AU - Thiesset HF -FAU - Box, Terry -AU - Box T -FAU - Hutson, William R -AU - Hutson WR -FAU - Lu, Jeffrey K -AU - Lu JK -FAU - Campsen, Jeffrey -AU - Campsen J -FAU - Sorensen, John B -AU - Sorensen JB -FAU - Kim, Robin D -AU - Kim RD -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20130416 -PL - Japan -TA - Surg Today -JT - Surgery today -JID - 9204360 -SB - IM -MH - Aortic Valve/*surgery -MH - Aortic Valve Stenosis/complications/*surgery -MH - End Stage Liver Disease/etiology/*surgery -MH - Heart Valve Prosthesis Implantation/*methods -MH - Hepatitis C, Chronic/complications -MH - Humans -MH - *Liver Transplantation -MH - Male -MH - Middle Aged -MH - Minimally Invasive Surgical Procedures/*methods -MH - Treatment Outcome -EDAT- 2013/04/17 06:00 -MHDA- 2014/09/30 06:00 -CRDT- 2013/04/17 06:00 -PHST- 2012/06/20 00:00 [received] -PHST- 2012/08/05 00:00 [accepted] -PHST- 2013/04/17 06:00 [entrez] -PHST- 2013/04/17 06:00 [pubmed] -PHST- 2014/09/30 06:00 [medline] -AID - 10.1007/s00595-013-0559-8 [doi] -PST - ppublish -SO - Surg Today. 2014 Mar;44(3):546-9. doi: 10.1007/s00595-013-0559-8. Epub 2013 Apr - 16. - -PMID- 28496734 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20201001 -IS - 1941-6911 (Print) -IS - 1941-6911 (Electronic) -IS - 1941-6911 (Linking) -VI - 4 -IP - 6 -DP - 2012 Apr-May -TI - Epicardial Fat and Atrial Fibrillation: A Review. -PG - 483 -LID - 10.4022/jafib.483 [doi] -LID - 483 -AB - Atrial fibrillation (AF) is a progressive disorder that increases with age. - Obesity is an important risk factor for AF. Pericardial fat is an active adipose - tissue in close proximity to the heart and has been shown to be a risk factor for - structural as well as coronary artery disease independent of body mass index. - Recent studies suggest a role of epicardial fat in atrial remodeling as well as - AF burden. This review will summarize the recent evidence linking epicardial fat - and AF. -FAU - Al Chekakie, M Obadah -AU - Al Chekakie MO -AD - University of Colorado, Denver, CO and. -FAU - Akar, Joseph G -AU - Akar JG -AD - Yale University School of Medicine, New Haven, CT. -LA - eng -PT - Journal Article -PT - Review -DEP - 20120414 -PL - United States -TA - J Atr Fibrillation -JT - Journal of atrial fibrillation -JID - 101514767 -PMC - PMC5153200 -EDAT- 2012/04/14 00:00 -MHDA- 2012/04/14 00:01 -PMCR- 2012/04/14 -CRDT- 2017/05/13 06:00 -PHST- 2011/11/29 00:00 [received] -PHST- 2012/01/13 00:00 [revised] -PHST- 2012/01/19 00:00 [accepted] -PHST- 2017/05/13 06:00 [entrez] -PHST- 2012/04/14 00:00 [pubmed] -PHST- 2012/04/14 00:01 [medline] -PHST- 2012/04/14 00:00 [pmc-release] -AID - 10.4022/jafib.483 [doi] -PST - epublish -SO - J Atr Fibrillation. 2012 Apr 14;4(6):483. doi: 10.4022/jafib.483. eCollection - 2012 Apr-May. - -PMID- 21247986 -OWN - NLM -STAT- MEDLINE -DCOM- 20110805 -LR - 20161125 -IS - 1477-111X (Electronic) -IS - 0267-6591 (Linking) -VI - 26 -IP - 3 -DP - 2011 May -TI - Spontaneous retrograde dissection of ascending aorta from descending thoracic - aorta--a case review. -PG - 215-22 -LID - 10.1177/0267659110395804 [doi] -AB - A 56-year-old man with sudden onset chest pain, absent right lower limb pulses - and ECG changes suggestive of inferior ST elevation MI underwent coronary - angiogram through the right radial artery with a view to primary percutaneous - coronary intervention (PCI). The left coronary angiogram demonstrated severe - proximal stenotic disease in the left anterior descending and circumflex coronary - arteries, but the right coronary artery could not be selectively cannulated. An - ascending aortogram to visualise the right coronary artery not only failed to - demonstrate it, but revealed, instead, a dissection flap in the ascending aorta, - arch and descending thoracic aorta, with moderately severe aortic regurgitation. - At operation, the patient was found to have an acute dissection of the ascending - aorta, arch and descending aorta with an entry tear in the descending aorta below - the left subclavian artery origin. Triple coronary artery bypass grafting with - re-suspension of the aortic valve, supracoronary replacement of the ascending - aorta and hemiarch and transaortic repair of the descending aortic tear was - performed. The patient made an uncomplicated recovery, with the re-appearance of - right limb pulses. A postoperative magnetic resonance (MR) scan revealed complete - thrombosis of the false channel in the residual arch and a considerably shrunken - false channel in the descending aorta and no aortic regurgitation. Retrograde - dissection of the ascending aorta from the descending aorta has been reported - infrequently in the past. We believe the scale of the problem has been - underestimated because of the failure to adopt open distal anastomosis routinely - in the past and, hence, failure to inspect the arch and the descending aorta - routinely, particularly when the intimal tear was not identified in the ascending - aorta. Retrograde dissection of the ascending aorta from an intimal tear in the - descending aorta, when identified as such, has been managed, either on the - principle of exclusion of the tear in the descending aorta by various elephant - trunk procedures and their variants or, alternatively, on the principle of - excision of the tear by extended one-stage aortic replacement, usually combined - with an elephant trunk procedure. Neither of these procedures is widely adopted, - owing to procedural, institutional and outcome considerations. We describe a - transaortic repair of the intimal tear in the descending aorta with supracoronary - interposition graft replacement of the ascending aorta and hemiarch with - excellent clinical and radiological result. We also review the diagnostic and - therapeutic approaches to this incompletely understood lethal disease. -FAU - Kaul, Pankaj -AU - Kaul P -AD - Department of Cardiac Surgery, Yorkshire Heart Centre, Leeds General Infirmary, - Great George Street, Leeds, UK. pankaj.kaul@leedsth.nhs.uk -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20110119 -PL - England -TA - Perfusion -JT - Perfusion -JID - 8700166 -SB - IM -MH - Aorta, Thoracic/diagnostic imaging/*surgery -MH - Coronary Angiography/methods -MH - Coronary Artery Bypass/*methods -MH - Humans -MH - Magnetic Resonance Angiography/methods -MH - Male -MH - Middle Aged -MH - Postoperative Complications/*diagnosis/etiology/*surgery -MH - Rupture, Spontaneous/*diagnosis/*surgery -MH - Thrombosis/*diagnosis/etiology/*surgery -EDAT- 2011/01/21 06:00 -MHDA- 2011/08/06 06:00 -CRDT- 2011/01/21 06:00 -PHST- 2011/01/21 06:00 [entrez] -PHST- 2011/01/21 06:00 [pubmed] -PHST- 2011/08/06 06:00 [medline] -AID - 0267659110395804 [pii] -AID - 10.1177/0267659110395804 [doi] -PST - ppublish -SO - Perfusion. 2011 May;26(3):215-22. doi: 10.1177/0267659110395804. Epub 2011 Jan - 19. - -PMID- 24198536 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20211021 -IS - 1178-6957 (Print) -IS - 1178-6957 (Electronic) -IS - 1178-6957 (Linking) -VI - 5 -DP - 2012 Oct 30 -TI - Understanding the application of stem cell therapy in cardiovascular diseases. -PG - 29-37 -LID - 10.2147/SCCAA.S28500 [doi] -AB - Throughout their lifetime, an individual may sustain many injuries and recover - spontaneously over a period of time, without even realizing the injury in the - first place. Wound healing occurs due to a proliferation of stem cells capable of - restoring the injured tissue. The ability of adult stem cells to repair tissue is - dependent upon the intrinsic ability of tissues to proliferate. The amazing - capacity of embryonic stem cells to give rise to virtually any type of tissue has - intensified the search for similar cell lineage in adults to treat various - diseases including cardiovascular diseases. The ability to convert adult stem - cells into pluripotent cells that resemble embryonic cells, and to transplant - those in the desired organ for regenerative therapy is very attractive, and may - offer the possibility of treating harmful disease-causing mutations. The race is - on to find the best cells for treatment of cardiovascular disease. There is a - need for the ideal stem cell, delivery strategies, myocardial retention, and time - of administration in the ideal patient population. There are multiple modes of - stem cell delivery to the heart with different cell retention rates that vary - depending upon method and site of injection, such as intra coronary, - intramyocardial or via coronary sinus. While there are crucial issues such as - retention of stem cells, microvascular plugging, biodistribution, homing to - myocardium, and various proapoptotic factors in the ischemic myocardium, the - regenerative potential of stem cells offers an enormous impact on clinical - applications in the management of cardiovascular diseases. -FAU - Sharma, Rakesh K -AU - Sharma RK -AD - University of Arkansas for Medical Sciences, Medical Center of South Arkansas, El - Dorado, AR, USA. -FAU - Voelker, Donald J -AU - Voelker DJ -FAU - Sharma, Roma -AU - Sharma R -FAU - Reddy, Hanumanth K -AU - Reddy HK -LA - eng -PT - Journal Article -PT - Review -DEP - 20121030 -PL - New Zealand -TA - Stem Cells Cloning -JT - Stem cells and cloning : advances and applications -JID - 101535817 -PMC - PMC3781763 -OTO - NOTNLM -OT - cardiomyopathy -OT - cardiovascular diseases -OT - myocardial infarction -OT - stem cell delivery -OT - stem cell therapy -EDAT- 2012/01/01 00:00 -MHDA- 2012/01/01 00:01 -PMCR- 2012/10/30 -CRDT- 2013/11/08 06:00 -PHST- 2013/11/08 06:00 [entrez] -PHST- 2012/01/01 00:00 [pubmed] -PHST- 2012/01/01 00:01 [medline] -PHST- 2012/10/30 00:00 [pmc-release] -AID - sccaa-5-029 [pii] -AID - 10.2147/SCCAA.S28500 [doi] -PST - epublish -SO - Stem Cells Cloning. 2012 Oct 30;5:29-37. doi: 10.2147/SCCAA.S28500. - -PMID- 23231771 -OWN - NLM -STAT- MEDLINE -DCOM- 20130703 -LR - 20250529 -IS - 1095-8584 (Electronic) -IS - 0022-2828 (Linking) -VI - 55 -DP - 2013 Feb -TI - A practical guide to metabolomic profiling as a discovery tool for human heart - disease. -PG - 2-11 -LID - S0022-2828(12)00428-2 [pii] -LID - 10.1016/j.yjmcc.2012.12.001 [doi] -AB - Metabolomics has refreshed interest in metabolism across biology and medicine, - particularly in the areas of functional genomics and biomarker discovery. In this - review we will discuss the experimental techniques and challenges involved in - metabolomic profiling and how these technologies have been applied to - cardiovascular disease. Open profiling and targeted approaches to metabolomics - are compared, focusing on high resolution NMR spectroscopy and mass spectrometry, - as well as discussing how to analyse the large amounts of data generated using - multivariate statistics. Finally, the current literature on metabolomic profiling - in human cardiovascular disease is reviewed to illustrate the diversity of - approaches, and discuss some of the key metabolites and pathways found to be - perturbed in plasma, urine and tissue from patients with these diseases. This - includes studies of coronary artery disease, myocardial infarction, and ischemic - heart disease. These studies demonstrate the potential of the technology for - biomarker discovery and elucidating metabolic mechanisms associated with given - pathologies, but also in some cases provide a warning of the pitfalls of poor - study design. This article is part of a Special Issue entitled "Focus on Cardiac - Metabolism". -CI - Copyright © 2012 Elsevier Ltd. All rights reserved. -FAU - Heather, Lisa C -AU - Heather LC -AD - Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, - Oxford OX1 3PT, UK. -FAU - Wang, Xinzhu -AU - Wang X -FAU - West, James A -AU - West JA -FAU - Griffin, Julian L -AU - Griffin JL -LA - eng -GR - MC_UP_A090_1006/MRC_/Medical Research Council/United Kingdom -GR - UD99999906/MRC_/Medical Research Council/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121208 -PL - England -TA - J Mol Cell Cardiol -JT - Journal of molecular and cellular cardiology -JID - 0262322 -RN - 0 (Biomarkers) -SB - IM -MH - Biomarkers/metabolism -MH - Heart Diseases/*metabolism -MH - Humans -MH - *Metabolome -MH - *Metabolomics/methods -EDAT- 2012/12/13 06:00 -MHDA- 2013/07/05 06:00 -CRDT- 2012/12/13 06:00 -PHST- 2012/05/28 00:00 [received] -PHST- 2012/11/30 00:00 [revised] -PHST- 2012/12/01 00:00 [accepted] -PHST- 2012/12/13 06:00 [entrez] -PHST- 2012/12/13 06:00 [pubmed] -PHST- 2013/07/05 06:00 [medline] -AID - S0022-2828(12)00428-2 [pii] -AID - 10.1016/j.yjmcc.2012.12.001 [doi] -PST - ppublish -SO - J Mol Cell Cardiol. 2013 Feb;55:2-11. doi: 10.1016/j.yjmcc.2012.12.001. Epub 2012 - Dec 8. - -PMID- 22335263 -OWN - NLM -STAT- MEDLINE -DCOM- 20120417 -LR - 20120216 -IS - 1532-0650 (Electronic) -IS - 0002-838X (Linking) -VI - 85 -IP - 3 -DP - 2012 Feb 1 -TI - Perioperative cardiac risk reduction. -PG - 239-46 -AB - Cardiovascular complications are the most common cause of perioperative morbidity - and mortality. Noninvasive stress testing is rarely helpful in assessing risk, - and for most patients there is no evidence that coronary revascularization - provides more protection against perioperative cardiovascular events than optimal - medical management. Patients likely to benefit from perioperative beta blockade - include those with stable coronary artery disease and multiple cardiac risk - factors. Perioperative beta blockers should be initiated weeks before surgery and - titrated to heart rate and blood pressure targets. The balance of benefits and - harms of perioperative beta-blocker therapy is much less favorable in patients - with limited cardiac risk factors and when initiated in the acute preoperative - period. Perioperative statin therapy is recommended for all patients undergoing - vascular surgery. When prescribed for the secondary prevention of cardiovascular - disease, aspirin should be continued in the perioperative period. -FAU - Holt, Natalie F -AU - Holt NF -AD - Yale University School of Medicine, New Haven, CT 06520, USA. - natalie.holt@post.harvard.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am Fam Physician -JT - American family physician -JID - 1272646 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Adrenergic beta-Antagonists/*therapeutic use -MH - *Cardiovascular Diseases/epidemiology/etiology/prevention & control -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Morbidity -MH - Perioperative Care/*methods -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Prognosis -MH - Risk Assessment/*methods -MH - *Surgical Procedures, Operative -MH - Survival Rate -MH - United States/epidemiology -EDAT- 2012/02/18 06:00 -MHDA- 2012/04/18 06:00 -CRDT- 2012/02/17 06:00 -PHST- 2012/02/17 06:00 [entrez] -PHST- 2012/02/18 06:00 [pubmed] -PHST- 2012/04/18 06:00 [medline] -AID - d10232 [pii] -PST - ppublish -SO - Am Fam Physician. 2012 Feb 1;85(3):239-46. - -PMID- 19946240 -OWN - NLM -STAT- MEDLINE -DCOM- 20100222 -LR - 20220408 -IS - 1643-3750 (Electronic) -IS - 1234-1010 (Linking) -VI - 15 -IP - 12 -DP - 2009 Dec -TI - Time for new indications for statins? -PG - MS1-5 -AB - The role of statins in the treatment and prevention of cardiovascular diseases, - such as coronary artery disease, acute coronary syndromes, diabetes or stroke is - well established. However, there are still some questions regarding the role of - statins in patients with heart failure, hypertension, atrial fibrillation and - chronic kidney disease (CKD). This editorial review discusses the current - evidence regarding the use of statins in patients with hypertension (with or - without dyslipidemia) or CKD. We need new large randomized clinical trials to - confirm the potentially beneficial positive results obtained so far. -FAU - Banach, Maciej -AU - Banach M -AD - Department of Hypertension, Medical University of Łódź, Łódź, Poland. - maciejbanach@aol.co.uk -FAU - Mikhailidis, Dimitri P -AU - Mikhailidis DP -FAU - Kjeldsen, Sverre E -AU - Kjeldsen SE -FAU - Rysz, Jacek -AU - Rysz J -LA - eng -PT - Editorial -PT - Review -PL - United States -TA - Med Sci Monit -JT - Medical science monitor : international medical journal of experimental and - clinical research -JID - 9609063 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Lipoproteins, LDL) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -CIN - Med Sci Monit. 2010 Mar;16(3):LE3-3. PMID: 20190691 -MH - Blood Pressure/drug effects -MH - Cardiovascular Diseases/drug therapy/prevention & control -MH - Cholesterol/blood -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & - dosage/*therapeutic use -MH - Hypertension/blood/*drug therapy/physiopathology -MH - Kidney Failure, Chronic/blood/*drug therapy -MH - Lipoproteins, LDL/blood -RF - 48 -EDAT- 2009/12/01 06:00 -MHDA- 2010/02/23 06:00 -CRDT- 2009/12/01 06:00 -PHST- 2009/12/01 06:00 [entrez] -PHST- 2009/12/01 06:00 [pubmed] -PHST- 2010/02/23 06:00 [medline] -AID - 878258 [pii] -PST - ppublish -SO - Med Sci Monit. 2009 Dec;15(12):MS1-5. - -PMID- 18026917 -OWN - NLM -STAT- MEDLINE -DCOM- 20080313 -LR - 20220408 -IS - 0946-2716 (Print) -IS - 0946-2716 (Linking) -VI - 85 -IP - 12 -DP - 2007 Dec -TI - Keeping the engine primed: HIF factors as key regulators of cardiac metabolism - and angiogenesis during ischemia. -PG - 1309-15 -AB - Myocardial ischemia, the most common cause of cardiac hypoxia in clinical - medicine, occurs when oxygen delivery cannot meet myocardial metabolic - requirements in the heart. This deficiency can result from either a reduced - supply of oxygen (decreased coronary bloodflow) or an increased myocardial demand - for oxygen (increased wall stress or afterload). Patients with stable coronary - artery disease as well as patients experiencing acute myocardial infarction can - experience episodes of severe ischemia. Although hypoxia is an obligatory - component, it is not the sole environmental stress experienced by the ischemic - heart. Reperfusion after ischemia is associated with increased oxidative stress - as the heart reverts to aerobic respiration and thereby generates toxic levels of - reactive oxygen species (ROS). During mild ischemia, mitochondrial function is - partially compromised and substrate preferences adapt to sustain adequate ATP - generation. With severe ischemia, mitochondrial function is markedly compromised - and anaerobic metabolism must provide energy no matter what the cost in - generation of toxic ROS adducts. Ischemia produces a variety of environmental - stresses that impair cardiovascular function. As a result, multiple signaling - pathways are activated in mammalian cells during ischemia/reperfusion injury in - an attempt to minimize cellular injury and maintain cardiac output. Amongst the - transcriptional regulators activated are members of the hypoxia inducible factor - (HIF) transcription factor family. HIF factors regulate a variety of genes that - affect a myriad of cellular processes including metabolism, angiogenesis, cell - survival, and oxygen delivery, all of which are important in the heart. In this - review, we will focus on the metabolic and angiogenic aspects of HIF biology as - they relate to the heart during ischemia. We will review the metabolic - requirements of the heart under normal as well as hypoxic conditions, the effects - of preconditioning and its regulation as it pertains to HIF biology, the apparent - roles of HIF-1 and HIF-2 in intermediary metabolism, and translational - applications of HIF-1 and HIF-2 biology to cardiac angiogenesis. Increased - understanding of the role of HIFs in cardiac ischemia will ultimately influence - clinical cardiovascular practice. -FAU - Shohet, Ralph V -AU - Shohet RV -AD - John A. Burns School of Medicine, Center for Cardiovascular Research, University - of Hawaii, 651 Ilalo St., Honolulu, HI 96813, USA, shohet@hawaii.edu -FAU - Garcia, Joseph A -AU - Garcia JA -LA - eng -GR - 1P50MH66172/MH/NIMH NIH HHS/United States -GR - AR050597-01A1/AR/NIAMS NIH HHS/United States -GR - HL073449/HL/NHLBI NIH HHS/United States -GR - HL080532/HL/NHLBI NIH HHS/United States -GR - RR16453/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20071120 -PL - Germany -TA - J Mol Med (Berl) -JT - Journal of molecular medicine (Berlin, Germany) -JID - 9504370 -RN - 0 (Basic Helix-Loop-Helix Transcription Factors) -RN - 0 (Hypoxia-Inducible Factor 1) -RN - 0 (Reactive Oxygen Species) -RN - 1B37H0967P (endothelial PAS domain-containing protein 1) -RN - 8L70Q75FXE (Adenosine Triphosphate) -RN - S88TT14065 (Oxygen) -SB - IM -MH - Adenosine Triphosphate/metabolism -MH - Animals -MH - Basic Helix-Loop-Helix Transcription Factors/genetics/*metabolism -MH - Coronary Vessels/*metabolism/physiopathology -MH - Energy Metabolism -MH - Humans -MH - Hypoxia/genetics/*metabolism/physiopathology -MH - Hypoxia-Inducible Factor 1/genetics/*metabolism -MH - Ischemic Preconditioning, Myocardial -MH - Mitochondria, Heart/metabolism -MH - Myocardial Ischemia/genetics/*metabolism/physiopathology -MH - Myocardial Reperfusion Injury/genetics/*metabolism/physiopathology/prevention & - control -MH - Myocardium/*metabolism -MH - *Neovascularization, Physiologic -MH - Oxidative Stress -MH - Oxygen/metabolism -MH - Reactive Oxygen Species/metabolism -MH - Signal Transduction -MH - Transcription, Genetic -RF - 74 -EDAT- 2007/11/21 09:00 -MHDA- 2008/03/14 09:00 -CRDT- 2007/11/21 09:00 -PHST- 2007/10/01 00:00 [received] -PHST- 2007/10/23 00:00 [accepted] -PHST- 2007/10/22 00:00 [revised] -PHST- 2007/11/21 09:00 [pubmed] -PHST- 2008/03/14 09:00 [medline] -PHST- 2007/11/21 09:00 [entrez] -AID - 10.1007/s00109-007-0279-x [doi] -PST - ppublish -SO - J Mol Med (Berl). 2007 Dec;85(12):1309-15. doi: 10.1007/s00109-007-0279-x. Epub - 2007 Nov 20. - -PMID- 18333354 -OWN - NLM -STAT- MEDLINE -DCOM- 20080506 -LR - 20131121 -IS - 1220-4749 (Print) -IS - 1220-4749 (Linking) -VI - 45 -IP - 3 -DP - 2007 -TI - Management of pulmonary arterial hypertension associated with congenital heart - disease. -PG - 229-34 -AB - Congenital heart diseases are the most common congenital malformations and - account for about eight cases per 1000 births and are often associated with - pulmonary arterial hypertension. Increased shear stress and the excess flow - through the pulmonary vascular bed due to a systemic-to-pulmonary shunt lead to - the development of pulmonary vascular disease and an increase in pulmonary - vascular resistance. Without surgical repair approximately 30% of patients - develop pulmonary vascular disease. Eisenmenger syndrome represents the extreme - end of pulmonary arterial hypertension with congenital heart disease. We - summarized the current therapeutic options for pulmonary arterial hypertension; - conventional treatments including calcium channel blockers, anticoagulation, - digitalis, diuretics, and new treatment: prostacyclin, bosentan, sildenafil, - ambrisentan. Preliminary data of new therapies are encouraging with disease - significantly improved natural history, but there is need for more evidence-based - data. -FAU - Togănel, Rodica -AU - Togănel R -AD - Institute of Cardiovasculare Diseases and Transplantation, Department of - Pediatric Cardiology, Târgu-Mureş, Romania. roditog@yahoo.com -FAU - Benedek, I -AU - Benedek I -FAU - Suteu, Carmen -AU - Suteu C -FAU - Blesneac, Cristina -AU - Blesneac C -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Rom J Intern Med -JT - Romanian journal of internal medicine = Revue roumaine de medecine interne -JID - 9304507 -RN - 0 (Calcium Channel Blockers) -RN - 0 (Endothelins) -RN - 0 (Phosphodiesterase 5 Inhibitors) -RN - 0 (Vasodilator Agents) -RN - 31C4KY9ESH (Nitric Oxide) -RN - DCR9Z582X0 (Epoprostenol) -SB - IM -MH - Calcium Channel Blockers/therapeutic use -MH - Coronary Circulation -MH - Drug Therapy, Combination -MH - Endothelins/pharmacology/therapeutic use -MH - Epoprostenol/pharmacology -MH - Heart Defects, Congenital/*complications/*drug therapy -MH - Humans -MH - Hypertension, Pulmonary/*drug therapy/*etiology -MH - Lung Transplantation -MH - Nitric Oxide/therapeutic use -MH - Phosphodiesterase 5 Inhibitors -MH - Vasodilator Agents/pharmacology/therapeutic use -RF - 22 -EDAT- 2008/03/13 09:00 -MHDA- 2008/05/07 09:00 -CRDT- 2008/03/13 09:00 -PHST- 2008/03/13 09:00 [pubmed] -PHST- 2008/05/07 09:00 [medline] -PHST- 2008/03/13 09:00 [entrez] -PST - ppublish -SO - Rom J Intern Med. 2007;45(3):229-34. - -PMID- 24036027 -OWN - NLM -STAT- MEDLINE -DCOM- 20140116 -LR - 20171028 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 62 -IP - 21 -DP - 2013 Nov 19 -TI - Cardiovascular care facts: a report from the national cardiovascular data - registry: 2011. -PG - 1931-1947 -LID - S0735-1097(13)05088-2 [pii] -LID - 10.1016/j.jacc.2013.05.099 [doi] -AB - OBJECTIVES: The aim of this report was to characterize the patients, - participating centers, and measures of quality of care and outcomes for 5 NCDR - (National Cardiovascular Data Registry) programs: 1) ACTION (Acute Coronary - Treatment and Intervention Outcomes Network) Registry-GWTG (Get With The - Guidelines) for acute coronary syndromes; 2) CathPCI Registry for coronary - angiography and percutaneous coronary intervention; 3) CARE (Carotid Artery - Revascularization and Endarterectomy) Registry for carotid revascularization; 4) - ICD Registry for implantable cardioverter defibrillators; and the 5) PINNACLE - (Practice INNovation And CLinical Excellence) Registry for outpatients with - cardiovascular disease (CVD). BACKGROUND: CVD is a leading cause of death and - disability in the United States. The quality of care for patients with CVD is - suboptimal. National registry programs, such as NCDR, permit assessments of the - quality of care and outcomes for broad populations of patients with CVD. METHODS: - For the year 2011, we assessed for each of the 5 NCDR programs: 1) demographic - and clinical characteristics of enrolled patients; 2) key characteristics of - participating centers; 3) measures of processes of care; and 4) patient outcomes. - For selected variables, we assessed trends over time. RESULTS: In 2011 ACTION - Registry-GWTG enrolled 119,967 patients in 567 hospitals; CathPCI enrolled - 632,557 patients in 1,337 hospitals; CARE enrolled 4,934 patients in 130 - hospitals; ICD enrolled 139,991 patients in 1,435 hospitals; and PINNACLE - enrolled 249,198 patients (1,436,328 individual encounters) in 74 practices - (1,222 individual providers). Data on performance metrics and outcomes, in some - cases risk-adjusted with validated NCDR models, are presented. CONCLUSIONS: The - NCDR provides a unique opportunity to understand the characteristics of large - populations of patients with CVD, the centers that provide their care, quality of - care provided, and important patient outcomes. -CI - Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Masoudi, Frederick A -AU - Masoudi FA -AD - Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, - Colorado; Colorado Cardiovascular Outcomes Research Consortium, Denver, Colorado. - Electronic address: fred.masoudi@ucdenver.edu. -FAU - Ponirakis, Angelo -AU - Ponirakis A -AD - American College of Cardiology Foundation, Washington, DC. -FAU - Yeh, Robert W -AU - Yeh RW -AD - Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts. -FAU - Maddox, Thomas M -AU - Maddox TM -AD - Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, - Colorado; Colorado Cardiovascular Outcomes Research Consortium, Denver, Colorado; - Department of Medicine, VA Eastern Colorado Health Care System, Denver, Colorado. -FAU - Beachy, Jim -AU - Beachy J -AD - American College of Cardiology Foundation, Washington, DC. -FAU - Casale, Paul N -AU - Casale PN -AD - The Heart Group of Lancaster General Health, Lancaster, Pennsylvania. -FAU - Curtis, Jeptha P -AU - Curtis JP -AD - Department of Medicine, Yale University, New Haven, Connecticut. -FAU - De Lemos, James -AU - De Lemos J -AD - Department of Medicine, University of Texas Southwestern, Dallas, Texas. -FAU - Fonarow, Gregg -AU - Fonarow G -AD - Department of Medicine, University of California-Los Angeles Medical Center, Los - Angeles, California. -FAU - Heidenreich, Paul -AU - Heidenreich P -AD - Department of Medicine, Veterans Affairs Palo Alto Medical Center, Palo Alto, - California. -FAU - Koutras, Christina -AU - Koutras C -AD - American College of Cardiology Foundation, Washington, DC. -FAU - Kremers, Mark -AU - Kremers M -AD - Mid Carolina Cardiology and Presbyterian Hospital, Charlotte, North Carolina. -FAU - Messenger, John -AU - Messenger J -AD - Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, - Colorado. -FAU - Moussa, Issam -AU - Moussa I -AD - Division of Cardiovascular Diseases, Mayo Clinic, Jacksonville, Florida. -FAU - Oetgen, William J -AU - Oetgen WJ -AD - American College of Cardiology Foundation, Washington, DC. -FAU - Roe, Matthew T -AU - Roe MT -AD - Duke Cardiovascular Research Institute, Durham, North Carolina. -FAU - Rosenfield, Kenneth -AU - Rosenfield K -AD - Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts. -FAU - Shields, Thomas P Jr -AU - Shields TP Jr -AD - American College of Cardiology Foundation, Washington, DC. -FAU - Spertus, John A -AU - Spertus JA -AD - Division of Cardiovascular Diseases, Mid-America Heart Institute, Kansas City, - Kansas. -FAU - Wei, Jessica -AU - Wei J -AD - American College of Cardiology Foundation, Washington, DC. -FAU - White, Christopher -AU - White C -AD - Department of Cardiovascular Diseases, Ochsner Clinic Foundation, New Orleans, - Louisiana. -FAU - Young, Christopher H -AU - Young CH -AD - The Moran Company, Arlington, Virginia. -FAU - Rumsfeld, John S -AU - Rumsfeld JS -AD - Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, - Colorado; Colorado Cardiovascular Outcomes Research Consortium, Denver, Colorado; - Department of Medicine, VA Eastern Colorado Health Care System, Denver, Colorado. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130918 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Cardiovascular Diseases/*surgery -MH - *Guideline Adherence -MH - Humans -MH - *Percutaneous Coronary Intervention -MH - *Registries -MH - Risk Factors -MH - United States -OTO - NOTNLM -OT - AMI -OT - CAS -OT - CMS -OT - Centers for Medicaid and Medicare Services -OT - ICD -OT - PCI -OT - acute myocardial infarction -OT - cardiovascular disease -OT - carotid artery stenting -OT - implantable cardioverter defibrillator -OT - percutaneous coronary intervention -OT - quality of care -OT - registries -OT - registry -EDAT- 2013/09/17 06:00 -MHDA- 2014/01/17 06:00 -CRDT- 2013/09/17 06:00 -PHST- 2013/04/26 00:00 [received] -PHST- 2013/05/07 00:00 [accepted] -PHST- 2013/09/17 06:00 [entrez] -PHST- 2013/09/17 06:00 [pubmed] -PHST- 2014/01/17 06:00 [medline] -AID - S0735-1097(13)05088-2 [pii] -AID - 10.1016/j.jacc.2013.05.099 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2013 Nov 19;62(21):1931-1947. doi: 10.1016/j.jacc.2013.05.099. - Epub 2013 Sep 18. - -PMID- 17360235 -OWN - NLM -STAT- MEDLINE -DCOM- 20071009 -LR - 20080131 -IS - 1443-9506 (Print) -IS - 1443-9506 (Linking) -VI - 16 -IP - 4 -DP - 2007 Aug -TI - What is the role of leukocyte depletion in cardiac surgery? -PG - 243-53 -AB - Leukocytes play an important pathogenic role in ischaemia-reperfusion injury. - During cardiopulmonary bypass, leukocyte filters have the potential to remove - leukocytes, thereby reducing contact of activated leukocytes with the endothelium - of target organs. Improvement in the safety and efficacy of commercially - available leukocyte filters in recent years has led to their increasing use in - cardiac surgery. However, the benefits have been inconsistent. Current evidence - suggests that leukocyte depletion may not have a significant impact in low risk - elective coronary artery bypass grafting but may be beneficial in valve surgery - and high-risk cardiac surgery. High-risk surgical groups that may benefit from - leukocyte filtration are those with left ventricular hypertrophy (LV mass>300 g), - poor ejection fraction (EF<40%), chronic obstructive airways disease (predicted - FEV1<75%), prolonged ischaemia (cross clamp time>120 min or cardiac - transplantation), paediatric cardiac surgery and patients in cardiogenic shock - requiring emergency coronary artery bypass grafting. Future trials should be - powered to detect important clinical end points and be designed to avoid - premature exhaustion of the filter. -FAU - Lim, Hou-Kiat -AU - Lim HK -AD - Cardiac Surgical Research Unit, Alfred Hospital, Melbourne, Australia. -FAU - Anderson, James -AU - Anderson J -FAU - Leong, Jee-Yoong -AU - Leong JY -FAU - Pepe, Salvatore -AU - Pepe S -FAU - Salamonsen, Robert F -AU - Salamonsen RF -FAU - Rosenfeldt, Franklin L -AU - Rosenfeldt FL -LA - eng -PT - Journal Article -PT - Review -DEP - 20070313 -PL - Australia -TA - Heart Lung Circ -JT - Heart, lung & circulation -JID - 100963739 -SB - IM -CIN - Heart Lung Circ. 2007 Oct;16(5):398-9; author reply 399-400. doi: - 10.1016/j.hlc.2007.06.520. PMID: 17660043 -MH - *Cardiac Surgical Procedures -MH - Cardiopulmonary Bypass -MH - Combined Modality Therapy -MH - Cost-Benefit Analysis -MH - Endothelium, Vascular/cytology -MH - Heart Diseases/physiopathology/surgery -MH - Humans -MH - *Leukocyte Reduction Procedures/economics/methods -MH - Myocardial Reperfusion Injury/physiopathology/prevention & control -MH - Risk Factors -RF - 42 -EDAT- 2007/03/16 09:00 -MHDA- 2007/10/10 09:00 -CRDT- 2007/03/16 09:00 -PHST- 2006/06/29 00:00 [received] -PHST- 2006/12/07 00:00 [revised] -PHST- 2007/01/07 00:00 [accepted] -PHST- 2007/03/16 09:00 [pubmed] -PHST- 2007/10/10 09:00 [medline] -PHST- 2007/03/16 09:00 [entrez] -AID - S1443-9506(07)00028-5 [pii] -AID - 10.1016/j.hlc.2007.01.003 [doi] -PST - ppublish -SO - Heart Lung Circ. 2007 Aug;16(4):243-53. doi: 10.1016/j.hlc.2007.01.003. Epub 2007 - Mar 13. - -PMID- 23192757 -OWN - NLM -STAT- MEDLINE -DCOM- 20130218 -LR - 20211021 -IS - 1524-4628 (Electronic) -IS - 0039-2499 (Linking) -VI - 44 -IP - 1 -DP - 2013 Jan -TI - Evolution of reperfusion therapies for acute brain and acute myocardial ischemia: - a systematic, comparative analysis. -PG - 94-8 -LID - 10.1161/STROKEAHA.112.666925 [doi] -AB - BACKGROUND AND PURPOSE: Early reperfusion is the most effective therapy for both - acute brain and cardiac ischemia. However, the cervicocephalic circulatory bed - offers more challenges to recanalization interventions. The historical - development of reperfusion interventions has not previously been systematically - compared. METHODS: Medline search identified all multi-arm, controlled trials of - coronary revascularization for acute myocardial infarction and multicenter trials - of cerebral revascularization for acute ischemic stroke reporting angiographic - reperfusion rates. RESULTS: Thirty-seven trials of coronary reperfusion enrolled - 10 908 patients from 1983 to 2009, and 10 trials of cerebral reperfusion enrolled - 1064 patients from 1992 to 2009. Coronary reperfusion trials included 10 of - intravenous fibrinolysis alone, 8 combined intravenous fibrinolysis and - percutaneous transluminal coronary angioplasty with or without stenting, 3 - intra-arterial fibrinolysis, and 16 percutaneous transluminal coronary - angioplasty with or without stenting. Cerebral reperfusion trials included 1 of - intravenous fibrinolysis alone, 3 intra-arterial fibrinolysis, 3 endovascular - device alone, and 3 of endovascular treatment ± intravenous fibrinolysis. In both - circulatory beds, endovascular treatments were more efficacious at achieving - reperfusion than peripherally administered fibrinolytics. In the coronary bed, - rates of achieved reperfusion began at high levels in the 1980s and improved - modestly over the subsequent 3 decades. In the cerebral bed, reperfusion rates - began at modest levels in the early 1990s and increased more slowly. Most - recently, in 2005 to 2009, cardiac reperfusion rates substantially exceeded - cerebral, partial reperfusion 86.1% versus 61.1%, complete reperfusion 78.6% - versus 23.4%. CONCLUSIONS: Reperfusion therapies developed more slowly and remain - less effective for cerebral than cardiac ischemia. Further, cerebral - circulation-specific technical advances are required for physicians to become as - capable at safely restoring blood flow to the ischemic brain as the ischemic - heart. -FAU - Patel, Richa D -AU - Patel RD -AD - UCLA Stroke Center, 710 Westwood Plaza, Los Angeles, CA 90095, USA. -FAU - Saver, Jeffrey L -AU - Saver JL -LA - eng -GR - P50 NS044378/NS/NINDS NIH HHS/United States -GR - U01 NS 44364/NS/NINDS NIH HHS/United States -PT - Comparative Study -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20121127 -PL - United States -TA - Stroke -JT - Stroke -JID - 0235266 -SB - IM -MH - Acute Disease -MH - Brain Ischemia/epidemiology/*surgery -MH - Humans -MH - Multicenter Studies as Topic/methods -MH - Myocardial Ischemia/epidemiology/*surgery -MH - Myocardial Reperfusion/*trends -EDAT- 2012/11/30 06:00 -MHDA- 2013/02/19 06:00 -CRDT- 2012/11/30 06:00 -PHST- 2012/11/30 06:00 [entrez] -PHST- 2012/11/30 06:00 [pubmed] -PHST- 2013/02/19 06:00 [medline] -AID - STROKEAHA.112.666925 [pii] -AID - 10.1161/STROKEAHA.112.666925 [doi] -PST - ppublish -SO - Stroke. 2013 Jan;44(1):94-8. doi: 10.1161/STROKEAHA.112.666925. Epub 2012 Nov 27. - -PMID- 17157232 -OWN - NLM -STAT- MEDLINE -DCOM- 20070227 -LR - 20061212 -IS - 1043-0679 (Print) -IS - 1043-0679 (Linking) -VI - 18 -IP - 2 -DP - 2006 Summer -TI - Current experience with percutaneous pulmonary valve implantation. -PG - 122-5 -AB - Transcatheter valve replacement has recently been introduced into clinical - practice and has the potential to transform the management of valvular heart - disease. To date, the largest human experience exists with percutaneous pulmonary - valve implantation in patients with repaired congenital heart disease who require - re-intervention to the right ventricular outflow tract. The application of this - approach, however, is presently restricted to certain right ventricular outflow - tract morphologies, because the device needs to be anchored safely to prevent - device dislodgement. Early results of percutaneous pulmonary valve implantation - show lower morbidity than surgery and significant early symptomatic improvement. - In the future, the challenge will be to extend percutaneous pulmonary valve - implantation to all patients with a clinical indication to delay or avoid repeat - open-heart surgery. -FAU - Nordmeyer, Johannes -AU - Nordmeyer J -AD - The Cardiac Unit, Institute of Child Health and Great Ormond Street Hospital for - Children, London, United Kingdom. NordmJ@gosh.nhs.uk -FAU - Coats, Louise -AU - Coats L -FAU - Bonhoeffer, Philipp -AU - Bonhoeffer P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Semin Thorac Cardiovasc Surg -JT - Seminars in thoracic and cardiovascular surgery -JID - 8917640 -SB - IM -MH - Coronary Angiography -MH - Heart Valve Prosthesis -MH - *Heart Valve Prosthesis Implantation/adverse effects -MH - Humans -MH - Length of Stay -MH - Prosthesis Design -MH - Pulmonary Valve/*surgery -MH - Pulmonary Valve Insufficiency/*surgery -MH - Stents -RF - 11 -EDAT- 2006/12/13 09:00 -MHDA- 2007/02/28 09:00 -CRDT- 2006/12/13 09:00 -PHST- 2006/07/21 00:00 [accepted] -PHST- 2006/12/13 09:00 [pubmed] -PHST- 2007/02/28 09:00 [medline] -PHST- 2006/12/13 09:00 [entrez] -AID - S1043-0679(06)00044-X [pii] -AID - 10.1053/j.semtcvs.2006.07.006 [doi] -PST - ppublish -SO - Semin Thorac Cardiovasc Surg. 2006 Summer;18(2):122-5. doi: - 10.1053/j.semtcvs.2006.07.006. - -PMID- 17943047 -OWN - NLM -STAT- MEDLINE -DCOM- 20071108 -LR - 20151119 -IS - 0038-4348 (Print) -IS - 0038-4348 (Linking) -VI - 100 -IP - 10 -DP - 2007 Oct -TI - Pharmacologic stress myocardial perfusion imaging. -PG - 1006-14; quiz 1004 -AB - Pharmacologic stress agents (dipyridamole, adenosine and dobutamine) allow - virtually all patients to be safely assessed for ischemic heart disease. These - agents have mild but significant side effects, mandating a thorough knowledge of - indications, contraindications, side effects and management before their use. - Adjunctive exercise improves image quality in vasodilator pharmacologic - myocardial perfusion imaging. Diabetics, especially women, have a much higher - cardiac event rate than nondiabetics for an equal amount of ischemia. They also - have a higher incidence of asymptomatic ischemia. There is growing support for - screening with myocardial perfusion imaging (MPI) for asymptomatic ischemia in - diabetics. The ability of MPI to identify hypocontractile but viable myocardium, - thus predicting improvement in myocardial function after revascularization, is - one of the most powerful uses of the modality. Vasodilator MPI should be used as - the initial test in patients with left bundle branch block or paced ventricular - rhythm, even if they are able to exercise. -FAU - Patel, Rakesh N -AU - Patel RN -AD - Department of Medicine and the Division of Cardiology, Medical College of - Georgia, Augusta, GA, USA. -FAU - Arteaga, Roque B -AU - Arteaga RB -FAU - Mandawat, Mahendra K -AU - Mandawat MK -FAU - Thornton, John W -AU - Thornton JW -FAU - Robinson, Vincent J B -AU - Robinson VJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - South Med J -JT - Southern medical journal -JID - 0404522 -RN - 0 (Vasodilator Agents) -SB - IM -CIN - South Med J. 2007 Oct;100(10):969-70. doi: 10.1097/SMJ.0b013e318153faec. PMID: - 17943036 -MH - Coronary Circulation/*physiology -MH - Diabetes Complications -MH - *Diagnostic Imaging -MH - Exercise Test/*methods -MH - Humans -MH - Myocardial Contraction/physiology -MH - Myocardial Ischemia/diagnosis -MH - *Vasodilator Agents -RF - 55 -EDAT- 2007/10/19 09:00 -MHDA- 2007/11/09 09:00 -CRDT- 2007/10/19 09:00 -PHST- 2007/10/19 09:00 [pubmed] -PHST- 2007/11/09 09:00 [medline] -PHST- 2007/10/19 09:00 [entrez] -AID - 00007611-200710000-00018 [pii] -AID - 10.1097/SMJ.0b013e318153f9c6 [doi] -PST - ppublish -SO - South Med J. 2007 Oct;100(10):1006-14; quiz 1004. doi: - 10.1097/SMJ.0b013e318153f9c6. - -PMID- 23182628 -OWN - NLM -STAT- MEDLINE -DCOM- 20130730 -LR - 20151119 -IS - 1879-0828 (Electronic) -IS - 0953-6205 (Linking) -VI - 24 -IP - 2 -DP - 2013 Mar -TI - Biomarkers of myocardial ischemia in the emergency room: cardiospecific troponin - and beyond. -PG - 97-9 -LID - S0953-6205(12)00285-3 [pii] -LID - 10.1016/j.ejim.2012.10.012 [doi] -AB - A timely and efficient diagnosis is critical in patients with chest pain, to - optimize the efficacy of myocardial revascularization in those with an acute - coronary syndrome, and offset the increasing overcrowding in the emergency room - by early discharge of subjects without myocardial ischemia. Although - cardiospecific troponins remain the biochemical gold standards for diagnosing an - acute coronary syndrome, several additional biomarkers have been proposed. As a - general rule, there are important issues that should be addressed when combining - an innovative diagnostic test with troponin, including a benchmark evaluation of - diagnostic performance, the impact on throughput and turnaround time, along with - the analytical features of the assay and the cost to benefit ratio of a - multi-marker approach. Despite a considerable amount of data has been published, - there is insufficient analytical and clinical evidence to support the use of most - of these novel biomarkers as surrogates or in combination with troponin for - diagnosing ischemic heart disease, especially when the latter is assessed with - the novel highly-sensitive immunoassays. -CI - Copyright © 2012 European Federation of Internal Medicine. Published by Elsevier - B.V. All rights reserved. -FAU - Lippi, Giuseppe -AU - Lippi G -AD - Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, - Italy. glippi@ao.pr.it -LA - eng -PT - Journal Article -PT - Review -DEP - 20121119 -PL - Netherlands -TA - Eur J Intern Med -JT - European journal of internal medicine -JID - 9003220 -RN - 0 (Biomarkers) -RN - 0 (Troponin) -SB - IM -MH - Biomarkers/*blood -MH - Diagnosis, Differential -MH - *Emergency Service, Hospital -MH - Humans -MH - Myocardial Ischemia/*blood/*diagnosis -MH - Severity of Illness Index -MH - Troponin/*blood -EDAT- 2012/11/28 06:00 -MHDA- 2013/07/31 06:00 -CRDT- 2012/11/28 06:00 -PHST- 2012/10/11 00:00 [received] -PHST- 2012/10/26 00:00 [revised] -PHST- 2012/10/31 00:00 [accepted] -PHST- 2012/11/28 06:00 [entrez] -PHST- 2012/11/28 06:00 [pubmed] -PHST- 2013/07/31 06:00 [medline] -AID - S0953-6205(12)00285-3 [pii] -AID - 10.1016/j.ejim.2012.10.012 [doi] -PST - ppublish -SO - Eur J Intern Med. 2013 Mar;24(2):97-9. doi: 10.1016/j.ejim.2012.10.012. Epub 2012 - Nov 19. - -PMID- 17338127 -OWN - NLM -STAT- MEDLINE -DCOM- 20070503 -LR - 20101118 -IS - 0043-5147 (Print) -IS - 0043-5147 (Linking) -VI - 59 -IP - 9-10 -DP - 2006 -TI - [Isolated right ventricular myocardial infarction in cardiosurgery practice]. -PG - 669-72 -AB - Isolated right ventricular myocardial infarction (RVMI) is a very rare - complication of ischemic heart disease. Generally it accompanies infero-posterior - or antero-septal myocardial infarction cases. Right ventricular myocardial - infarction is a strong predictor of acute right ventricular failure, - bradyarrythmia, ischemic and mechanical complications and is frequently - complicated by cardiogenic shock which often leads to death. Acute right - ventricular ischemia (RVI) and RVMI are big problem particularly during and early - post-operative cardiosurgery procedures. Atherosclerotic changes and heart blood - flow disturbances predispose to RVI or RVMI that occur more often in - cardiosurgical patients, especially in early postoperative period. On the other - hand early intraoperative diagnosis and longer reperfusion period result in the - correction of heart function and better prognosis. -FAU - Czajkowski, Marek -AU - Czajkowski M -AD - Z Kliniki Kardiochirurgii Akademii Medycznej im. Feliksa Skubiszewskiego w - Lublinie mczajkowski@interia.pl -FAU - Gniot, Jacek -AU - Gniot J -FAU - Wysokrński, Andrzej -AU - Wysokrński A -FAU - Biernacka, Jadwiga -AU - Biernacka J -FAU - Dabrowski, Wojciech -AU - Dabrowski W -FAU - Drozd, Jakub -AU - Drozd J -FAU - Rzecki, Ziemowit -AU - Rzecki Z -FAU - Krawczyk, Elibieta -AU - Krawczyk E -FAU - Jendrej, Janusz -AU - Jendrej J -FAU - Staika, Janusz -AU - Staika J -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Zawał prawej komory w praktyce kardiochirurgicznej. -PL - Poland -TA - Wiad Lek -JT - Wiadomosci lekarskie (Warsaw, Poland : 1960) -JID - 9705467 -SB - IM -MH - Angioplasty, Balloon, Coronary -MH - Arrhythmias, Cardiac/mortality/*therapy -MH - *Cardiac Surgical Procedures -MH - Comorbidity -MH - Electrocardiography -MH - Humans -MH - Myocardial Infarction/*mortality/*therapy -MH - Prognosis -MH - Shock, Cardiogenic/mortality/therapy -MH - Thrombolytic Therapy/methods -MH - Ventricular Dysfunction, Right/diagnosis/*epidemiology/*therapy -RF - 18 -EDAT- 2007/03/07 09:00 -MHDA- 2007/05/04 09:00 -CRDT- 2007/03/07 09:00 -PHST- 2007/03/07 09:00 [pubmed] -PHST- 2007/05/04 09:00 [medline] -PHST- 2007/03/07 09:00 [entrez] -PST - ppublish -SO - Wiad Lek. 2006;59(9-10):669-72. - -PMID- 17682844 -OWN - NLM -STAT- MEDLINE -DCOM- 20071128 -LR - 20181113 -IS - 0165-7380 (Print) -IS - 0165-7380 (Linking) -VI - 31 Suppl 1 -DP - 2007 Aug -TI - Animal models of dilated cardiomyopathy for translational research. -PG - 35-41 -AB - Animal models of cardiovascular disease have proved critically important for the - discovery of pathophysiological mechanisms and for the advancement of diagnosis - and therapy. They offer a number of advantages, principally the availability of - adequate healthy controls and the absence of confounding factors such as marked - differences in age, concomitant pathologies and pharmacological treatments. - Dilated cardiomyopathy (DCM) is the third cause of heart failure (HF) and is - characterized by progressive ventricular dilation and functional impairment in - the absence of coronary lesions and/or hypertension. Over the past thirty years, - investigators have developed numerous small and large animal models to study this - very complex syndrome. Genetically modified mice are the most widely and - intensively utilized research animals and allow high throughput studies on DCM. - However, to translate discoveries from basic science into medical applications, - research in large animal models becomes a necessary step. An accurate large - animal model of DCM is pacing-induced HF. It is obtained by continuous cardiac - pacing at a frequency three- to fourfold higher than the spontaneous heart rate - and is mostly applied to dogs, but also to pigs, sheep and monkeys. To date, this - model can still be considered a gold standard in HF research. -FAU - Recchia, F A -AU - Recchia FA -AD - Scuola Superiore Sant'Anna, Sector of Medicine, Pisa, Italy. f.recchia@sssup.it -FAU - Lionetti, V -AU - Lionetti V -LA - eng -PT - Journal Article -PT - Review -PL - Switzerland -TA - Vet Res Commun -JT - Veterinary research communications -JID - 8100520 -SB - IM -MH - Animals -MH - *Biomedical Research -MH - *Cardiomyopathy, Dilated -MH - *Disease Models, Animal -RF - 29 -EDAT- 2007/10/10 09:00 -MHDA- 2007/12/06 09:00 -CRDT- 2007/10/10 09:00 -PHST- 2007/10/10 09:00 [pubmed] -PHST- 2007/12/06 09:00 [medline] -PHST- 2007/10/10 09:00 [entrez] -AID - 10.1007/s11259-007-0005-8 [doi] -PST - ppublish -SO - Vet Res Commun. 2007 Aug;31 Suppl 1:35-41. doi: 10.1007/s11259-007-0005-8. - -PMID- 23227283 -OWN - NLM -STAT- MEDLINE -DCOM- 20130523 -LR - 20211021 -IS - 1947-6108 (Electronic) -IS - 1947-6094 (Print) -IS - 1947-6108 (Linking) -VI - 8 -IP - 3 -DP - 2012 Jul-Sep -TI - The 2012 ACCF/AHA Focused Update of the Unstable Angina/Non-ST-Elevation - Myocardial Infarction (UA/NSTEMI) Guideline: a critical appraisal. -PG - 26-30 -AB - The American College of Cardiology Foundation (ACCF) and the American Heart - Association (AHA) recently published the 2012 ACCF/AHA Focused Update of the - Guidelines for the Management of Patients with Unstable Angina and - Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing - the 2011 Update).(1) These guidelines were developed in collaboration with - multiple societies and represent an important landmark in the management of - patients with unstable angina (UA) and non-ST-elevation myocardial infarction - (NSTEMI). This paper provides a critical overview of some of the clinically - relevant novel and modified recommendations proposed by the updated guideline. -FAU - Jneid, Hani -AU - Jneid H -AD - Baylor College of Medicine, Michael E. DeBakey VA Medical Center, Houston, TX, - USA. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Methodist Debakey Cardiovasc J -JT - Methodist DeBakey cardiovascular journal -JID - 101508600 -SB - IM -MH - American Heart Association -MH - Angina, Unstable/*surgery -MH - Cardiology -MH - *Disease Management -MH - *Electrocardiography -MH - Humans -MH - Myocardial Infarction/*surgery -MH - Myocardial Revascularization/*standards -MH - *Practice Guidelines as Topic -MH - United States -PMC - PMC3487574 -OTO - NOTNLM -OT - P2Y12 receptor inhibitors -OT - acute coronary syndrome -OT - antiplatelet -OT - clopidogrel -OT - invasive strategy -OT - myocardial infarction -OT - prasugrel -OT - revascularization -OT - ticagrelor -OT - unstable angina -EDAT- 2012/12/12 06:00 -MHDA- 2013/05/25 06:00 -PMCR- 2012/07/01 -CRDT- 2012/12/11 06:00 -PHST- 2012/12/11 06:00 [entrez] -PHST- 2012/12/12 06:00 [pubmed] -PHST- 2013/05/25 06:00 [medline] -PHST- 2012/07/01 00:00 [pmc-release] -AID - MDCVJ_0803n [pii] -AID - 10.14797/mdcj-8-3-26 [doi] -PST - ppublish -SO - Methodist Debakey Cardiovasc J. 2012 Jul-Sep;8(3):26-30. doi: - 10.14797/mdcj-8-3-26. - -PMID- 17459669 -OWN - NLM -STAT- MEDLINE -DCOM- 20070914 -LR - 20161126 -IS - 0006-3002 (Print) -IS - 0006-3002 (Linking) -VI - 1772 -IP - 7 -DP - 2007 Jul -TI - Platelets: the universal killer? -PG - 715-7 -AB - For many, the final terminal event in life is cessation of the heart beat. In - turn, this is generally because this organ has been deprived of oxygen and - glucose as the blood can no longer deliver these requirements to the myocardium. - The principal reason for this is blockage of one or more coronary arteries or - arterioles by platelet rich thrombus. A similar process exists for the - pathophysiology of stroke--a disabilitating and often fatal event caused by - occlusion or rupture of arteries in, or feeding, the brain. These scenarios are - best developed in cardiovascular disease, but apply to almost all human disease. - Therefore, the ultimate culprit for these major life events is the overactive - platelet-too ready to form an inappropriate thrombus. Thus, one way forward in - postponing an occlusive thrombotic event is to minimise platelet activation, new - tools and treatments for which are eagerly sought. -FAU - Blann, Andrew D -AU - Blann AD -AD - Haemostasis, Thrombosis and Vascular Biology Unit, University Department of - Medicine, City Hospital, Birmingham, B18 7QH, UK. a.blann@bham.ac.uk -LA - eng -PT - Journal Article -PT - Review -DEP - 20070312 -PL - Netherlands -TA - Biochim Biophys Acta -JT - Biochimica et biophysica acta -JID - 0217513 -SB - IM -MH - Blood Platelets/*physiology -MH - Humans -MH - Stroke/*physiopathology -MH - Thrombosis/*physiopathology -RF - 23 -EDAT- 2007/04/27 09:00 -MHDA- 2007/09/15 09:00 -CRDT- 2007/04/27 09:00 -PHST- 2007/02/26 00:00 [received] -PHST- 2007/03/05 00:00 [revised] -PHST- 2007/03/05 00:00 [accepted] -PHST- 2007/04/27 09:00 [pubmed] -PHST- 2007/09/15 09:00 [medline] -PHST- 2007/04/27 09:00 [entrez] -AID - S0925-4439(07)00076-2 [pii] -AID - 10.1016/j.bbadis.2007.03.001 [doi] -PST - ppublish -SO - Biochim Biophys Acta. 2007 Jul;1772(7):715-7. doi: 10.1016/j.bbadis.2007.03.001. - Epub 2007 Mar 12. - -PMID- 18386601 -OWN - NLM -STAT- MEDLINE -DCOM- 20080507 -LR - 20080404 -IS - 1220-4749 (Print) -IS - 1220-4749 (Linking) -VI - 44 -IP - 3 -DP - 2006 -TI - Therapeutical perspectives for apoptosis modulation in cardiovascular disease. -PG - 213-22 -AB - Apoptosis, or programmed cell death, is an active form of cell death, distinct - from necrosis, through which multicellular organisms dispose of cells - efficiently. Implication of apoptosis in the initiation and progression of many - cardiovascular diseases, such as heart failure, systemic hypertension, coronary - artery disease, has raised the possibility to elaborate new classes of medication - to modulate this process. We review the most important drugs used in - cardiovascular diseases and their interference with apoptosis, demonstrated by - clinical studies as well as the involved mechanisms. We also analyze new - molecules which protect cells from apoptosis and may therefore be clinically - useful, as a new class of medication. -FAU - Ginghină, Carmen -AU - Ginghină C -AD - C.C. Iliescu Institute of Cardiovascular Diseases, Bucharest, Romania. - ginghina@astral.ro -FAU - Crăciunescu, Ileana -AU - Crăciunescu I -FAU - Iorga, V -AU - Iorga V -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Rom J Intern Med -JT - Romanian journal of internal medicine = Revue roumaine de medecine interne -JID - 9304507 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Apoptosis/*drug effects -MH - Cardiovascular Agents/*pharmacology/therapeutic use -MH - Cardiovascular Diseases/*drug therapy/etiology/pathology -MH - Humans -RF - 23 -EDAT- 2008/04/05 09:00 -MHDA- 2008/05/08 09:00 -CRDT- 2008/04/05 09:00 -PHST- 2008/04/05 09:00 [pubmed] -PHST- 2008/05/08 09:00 [medline] -PHST- 2008/04/05 09:00 [entrez] -PST - ppublish -SO - Rom J Intern Med. 2006;44(3):213-22. - -PMID- 23745812 -OWN - NLM -STAT- MEDLINE -DCOM- 20140207 -LR - 20190907 -IS - 1873-4294 (Electronic) -IS - 1568-0266 (Linking) -VI - 13 -IP - 13 -DP - 2013 -TI - MicroRNAs in cardiovascular therapeutics. -PG - 1605-18 -AB - Recent research reveals the crucial role microRNAs (miRNAs) in the pathogenesis - and progression of many pathological conditions, including cardiovascular - diseases. It is widely documented that miRNAs represent critical regulators of - cardiovascular function and participate in almost all aspects of cardiovascular - biology. In particular, they are involved in several pathophysiological pathways - of various manifestations of cardiovascular disease, such as coronary artery - disease, heart failure, stroke, diabetes mellitus, arterial hypertension and - cardiac arrhythmias. In the present article we review the available literature - regarding to the role of miRNAs in certain cardiovascular conditions. Moreover, - we discuss the therapeutic potential of miRNAs for treating cardiovascular - diseases and we attempt to highlight future directions. -FAU - Siasos, Gerasimos -AU - Siasos G -AD - 1st Cardiology Department, University of Athens Medical School, Hippokration - Hospital, Athens, Greece. gsiasos@med.uoa.gr -FAU - Tousoulis, Dimitris -AU - Tousoulis D -FAU - Tourikis, Panagiotis -AU - Tourikis P -FAU - Mazaris, Savas -AU - Mazaris S -FAU - Zakynthinos, Giorgos -AU - Zakynthinos G -FAU - Oikonomou, Evangelos -AU - Oikonomou E -FAU - Kokkou, Eleni -AU - Kokkou E -FAU - Kollia, Christina -AU - Kollia C -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Top Med Chem -JT - Current topics in medicinal chemistry -JID - 101119673 -RN - 0 (MicroRNAs) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*drug therapy/*metabolism/physiopathology -MH - Humans -MH - MicroRNAs/*metabolism -EDAT- 2013/06/12 06:00 -MHDA- 2014/02/08 06:00 -CRDT- 2013/06/11 06:00 -PHST- 2013/03/14 00:00 [received] -PHST- 2013/04/29 00:00 [revised] -PHST- 2013/02/13 00:00 [accepted] -PHST- 2013/06/11 06:00 [entrez] -PHST- 2013/06/12 06:00 [pubmed] -PHST- 2014/02/08 06:00 [medline] -AID - CTMC-EPUB-20130531-13 [pii] -AID - 10.2174/15680266113139990109 [doi] -PST - ppublish -SO - Curr Top Med Chem. 2013;13(13):1605-18. doi: 10.2174/15680266113139990109. - -PMID- 17197251 -OWN - NLM -STAT- MEDLINE -DCOM- 20070504 -LR - 20090812 -IS - 1566-0702 (Print) -IS - 1566-0702 (Linking) -VI - 132 -IP - 1-2 -DP - 2007 Mar 30 -TI - The impact of Cardiovascular Autonomic Neuropathy in diabetes: is it associated - with left ventricular dysfunction? -PG - 1-7 -AB - Cardiovascular Autonomic Neuropathy (CAN) is one of the least understood of all - serious complications of diabetes. Besides increasing mortality, CAN may have - various clinical sequelae including exercise intolerance, arrhythmias and - painless myocardial infarction. But does it also cause left ventricular - dysfunction? Patients with diabetes have a greater risk of developing congestive - heart failure. Coronary artery disease and hypertension have been notorious in - causing left ventricular dysfunction in many of these patients. However, even in - their absence, diabetes itself, through several studies, has been proposed to - cause the controversial entity, Diabetic Cardiomyopathy (DCM). Various mechanisms - have been suggested. CAN through alteration in myocardial blood flow and - sympathetic denervation, and through changes in myocardial neurotransmitters, - including catecholamines and neurotransmitters of the neuropeptidergic system, - has been and is still being studied as one of the main mechanisms to cause left - ventricular dysfunction. Earlier detection of CAN and instant initiation of - upcoming treatments may be a way to help prevent DCM, and thus improve the - morbidity and mortality this causes to patients with diabetes. -FAU - Debono, Miguel -AU - Debono M -AD - Department of Diabetes and Endocrinology Luton and Dunstable Hospital NHS Trust - Lewsey Road, Luton LU4 ODZ, United Kingdom. miggy08@di-ve.com -FAU - Cachia, Elaine -AU - Cachia E -LA - eng -PT - Journal Article -PT - Review -DEP - 20070102 -PL - Netherlands -TA - Auton Neurosci -JT - Autonomic neuroscience : basic & clinical -JID - 100909359 -SB - IM -MH - Animals -MH - Autonomic Nervous System Diseases/*etiology/*physiopathology -MH - Cardiovascular Diseases/etiology/physiopathology -MH - Coronary Vessels -MH - Diabetic Neuropathies/*complications/*physiopathology -MH - Heart/innervation -MH - Humans -MH - Ventricular Dysfunction, Left/*etiology/*physiopathology -RF - 46 -EDAT- 2007/01/02 09:00 -MHDA- 2007/05/05 09:00 -CRDT- 2007/01/02 09:00 -PHST- 2006/06/29 00:00 [received] -PHST- 2006/11/12 00:00 [revised] -PHST- 2006/11/14 00:00 [accepted] -PHST- 2007/01/02 09:00 [pubmed] -PHST- 2007/05/05 09:00 [medline] -PHST- 2007/01/02 09:00 [entrez] -AID - S1566-0702(06)00298-0 [pii] -AID - 10.1016/j.autneu.2006.11.003 [doi] -PST - ppublish -SO - Auton Neurosci. 2007 Mar 30;132(1-2):1-7. doi: 10.1016/j.autneu.2006.11.003. Epub - 2007 Jan 2. - -PMID- 22542041 -OWN - NLM -STAT- MEDLINE -DCOM- 20121002 -LR - 20161125 -IS - 1444-2892 (Electronic) -IS - 1443-9506 (Linking) -VI - 21 -IP - 6-7 -DP - 2012 Jun -TI - Perspectives in interventional electrophysiology in children and those with - congenital heart disease: electrophysiology in children. -PG - 413-20 -LID - 10.1016/j.hlc.2012.04.003 [doi] -AB - Recent developments in paediatric pacing and ablation of arrhythmia substrate - have been characterised by adoption and modification of techniques used in - adults. Infants, small children and those of all ages with congenital heart - disease are a patient group with a higher risk profile needing a special - approach. Current success rates for catheter ablation are high and major - complication rates are low. Important issues with respect to long-term outcome - include questions about coronary injury, long-term effects of radiation exposure - and late recurrence. Non-fluoroscopic electro-anatomical mapping systems (3D - systems), cryo-ablation and remote navigation are techniques recently improved - such that it is possible to potentially reduce fluoroscopy and complications. - Pacing in young children and congenital heart disease often warrants an - epicardial approach to avoid embolism, venous occlusion and lead failure related - to growth. Defibrillator and resynchronisation therapy are increasingly important - tools to reduce mortality, although the indications are not as clear as in adult - patients without congenital heart disease. -CI - Copyright © 2012 Australian and New Zealand Society of Cardiac and Thoracic - Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). - Published by Elsevier B.V. All rights reserved. -FAU - Pflaumer, Andreas -AU - Pflaumer A -AD - The Royal Children's Hospital Melbourne, Australia. andreas.pflaumer@rch.org.au -FAU - Chard, Richard -AU - Chard R -FAU - Davis, Andrew M -AU - Davis AM -LA - eng -PT - Journal Article -PT - Review -DEP - 20120426 -PL - Australia -TA - Heart Lung Circ -JT - Heart, lung & circulation -JID - 100963739 -SB - IM -MH - Adolescent -MH - Adult -MH - Cardiac Resynchronization Therapy/adverse effects/*methods -MH - Catheter Ablation/adverse effects/*methods -MH - Child -MH - Child, Preschool -MH - *Defibrillators, Implantable -MH - *Electrophysiologic Techniques, Cardiac -MH - *Electrophysiological Phenomena -MH - Female -MH - Heart Defects, Congenital/mortality/*physiopathology/*therapy -MH - Humans -MH - Infant -MH - Male -EDAT- 2012/05/01 06:00 -MHDA- 2012/10/04 06:00 -CRDT- 2012/05/01 06:00 -PHST- 2012/02/11 00:00 [received] -PHST- 2012/04/02 00:00 [revised] -PHST- 2012/04/02 00:00 [accepted] -PHST- 2012/05/01 06:00 [entrez] -PHST- 2012/05/01 06:00 [pubmed] -PHST- 2012/10/04 06:00 [medline] -AID - S1443-9506(12)00211-9 [pii] -AID - 10.1016/j.hlc.2012.04.003 [doi] -PST - ppublish -SO - Heart Lung Circ. 2012 Jun;21(6-7):413-20. doi: 10.1016/j.hlc.2012.04.003. Epub - 2012 Apr 26. - -PMID- 21446900 -OWN - NLM -STAT- MEDLINE -DCOM- 20120627 -LR - 20191112 -IS - 2212-4063 (Electronic) -IS - 1871-529X (Linking) -VI - 11 -IP - 1 -DP - 2011 Mar 1 -TI - Myths and facts concerning the use of statins in very old patients. -PG - 17-23 -AB - As population grows old, the number of persons at risk of cardiovascular events - also grows. Though octogenarians form a small percentage of the general - population their absolute risk of coronary and cerebrovascular disease is high, - but there is still some doubt as to whether high plasma cholesterol levels - increase vascular risk in this age group, as published data are conflicting. - There is evidence that elevated plasma cholesterol increases the risk of coronary - artery disease in older adults, and an inverse linear relationship was found - between HDL cholesterol levels and the risk of mortality from ischemic heart - disease in all age groups. The relationship between total plasma cholesterol and - the risk of death from ischemic stroke is weak in younger populations and is even - lower in people between 70 and 89 years, and is inverse for hemorrhagic stroke. - However, studies showed that statin treatment lowers the risk of ischemic stroke, - independently of age. Statins are underused in the elderly, perhaps because of - lack of perception of the real vascular risk of older adults, concerns about - statin efficacy or safety in this population, or the increase of comorbidities - and polypharmacy which could affect adherence to drug-treatment. Trials designed - to address this issues are urgently needed, in order to be able to make - evidence-guided decisions on lipid management of the elderly. -FAU - Alonzo, Claudia B -AU - Alonzo CB -AD - Internal Medicine Unit, Geriatric Medicine. PROTEGE-ACV Program, Hospital - Italiano de Buenos Aires, Argentina. claudia.alonzo@hospitalitaliano.org.ar -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PL - United Arab Emirates -TA - Cardiovasc Hematol Disord Drug Targets -JT - Cardiovascular & hematological disorders drug targets -JID - 101269160 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Age Factors -MH - Aged -MH - Aged, 80 and over -MH - Female -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage/adverse - effects -MH - Male -MH - Risk Factors -EDAT- 2011/03/31 06:00 -MHDA- 2012/06/28 06:00 -CRDT- 2011/03/31 06:00 -PHST- 2010/12/07 00:00 [received] -PHST- 2011/03/13 00:00 [revised] -PHST- 2011/03/16 00:00 [accepted] -PHST- 2011/03/31 06:00 [entrez] -PHST- 2011/03/31 06:00 [pubmed] -PHST- 2012/06/28 06:00 [medline] -AID - BSP/CHDDT/E-Pub/00036 [pii] -AID - 10.2174/187152911795945141 [doi] -PST - ppublish -SO - Cardiovasc Hematol Disord Drug Targets. 2011 Mar 1;11(1):17-23. doi: - 10.2174/187152911795945141. - -PMID- 17268210 -OWN - NLM -STAT- MEDLINE -DCOM- 20070419 -LR - 20191110 -IS - 1527-5299 (Print) -IS - 1527-5299 (Linking) -VI - 13 -IP - 1 -DP - 2007 Jan-Feb -TI - B-type natriuretic peptide: a critical review. -PG - 48-52 -AB - Natriuretic peptides have been used as tools for diagnosis and risk - stratification in patients with heart failure, myocardial infarction, and - unstable coronary syndromes, as well as in the general population. The biology of - intra-assay and intraindividual variations of plasma natriuretic peptide levels - is still not clearly understood despite their broad adoption in clinical - practice. Interpretation of plasma natriuretic peptide levels therefore requires - availability of the clinical context as well as considerations of various - confounders. It is clear that high plasma natriuretic peptide levels can be - highly suggestive of underlying myocardial disease, although a specific - underlying cause cannot be identified based on the test results. The potential - use of natriuretic peptide levels to monitor and guide patient management or - detect subclinical disease states is currently under investigation. -FAU - Tang, W H Wilson -AU - Tang WH -AD - Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, - Cleveland, OH 44195, USA. tangw@ccf.org -LA - eng -GR - M01 RR018390/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Congest Heart Fail -JT - Congestive heart failure (Greenwich, Conn.) -JID - 9714174 -RN - 0 (Biomarkers) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Biomarkers/blood -MH - Disease Progression -MH - Heart Failure/*blood/diagnosis/epidemiology -MH - Humans -MH - Natriuretic Peptide, Brain/*blood -MH - Prognosis -MH - Severity of Illness Index -RF - 52 -EDAT- 2007/02/03 09:00 -MHDA- 2007/04/20 09:00 -CRDT- 2007/02/03 09:00 -PHST- 2007/02/03 09:00 [pubmed] -PHST- 2007/04/20 09:00 [medline] -PHST- 2007/02/03 09:00 [entrez] -AID - 10.1111/j.1527-5299.2007.05622.x [doi] -PST - ppublish -SO - Congest Heart Fail. 2007 Jan-Feb;13(1):48-52. doi: - 10.1111/j.1527-5299.2007.05622.x. - -PMID- 23294824 -OWN - NLM -STAT- MEDLINE -DCOM- 20130828 -LR - 20231120 -IS - 1477-2566 (Electronic) -IS - 1465-3249 (Linking) -VI - 15 -IP - 4 -DP - 2013 Apr -TI - Critical path in cardiac stem cell therapy: an update on cell delivery. -PG - 399-415 -LID - S1465-3249(12)00032-1 [pii] -LID - 10.1016/j.jcyt.2012.11.003 [doi] -AB - Despite optimal medical therapy, cardiovascular disease remains a leading cause - of morbidity and mortality worldwide. One emerging therapeutic approach for - treatment of cardiomyopathies is stem cell therapy. Use of stem cells for - regenerative medicine has quickly evolved over the last decade. On the basis of - encouraging pre-clinical results, stem cell therapy has developed rapidly into a - potentially promising treatment for ischemic heart disease, myocardial infarction - and congestive heart failure. In this review, we summarize the current - state-of-the-art of stem cell therapy and compare collective experiences gleaned - from trials using intravenous, intra-coronary and intra-myocardial delivery in - exacting credible benefits. We discuss implications of clinical outcomes reported - in relation to the delivered stem cells as probable destiny therapy for - cardiovascular repair. -CI - Copyright © 2013 International Society for Cellular Therapy. Published by - Elsevier Inc. All rights reserved. -FAU - Shim, Winston -AU - Shim W -AD - Research and Development Unit, National Heart Centre Singapore, Singapore. - winston.shim.s.n@nhcs.com.sg -FAU - Mehta, Ashish -AU - Mehta A -FAU - Wong, Philip -AU - Wong P -FAU - Chua, Terrance -AU - Chua T -FAU - Koh, Tian Hai -AU - Koh TH -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130105 -PL - England -TA - Cytotherapy -JT - Cytotherapy -JID - 100895309 -SB - IM -MH - Administration, Intravenous -MH - Cardiomyopathies/*therapy -MH - Heart -MH - Heart Failure/therapy -MH - Humans -MH - Myocardial Infarction/therapy -MH - *Regeneration -MH - Regenerative Medicine -MH - Stem Cell Transplantation/*methods -MH - *Stem Cells -EDAT- 2013/01/09 06:00 -MHDA- 2013/08/29 06:00 -CRDT- 2013/01/09 06:00 -PHST- 2012/07/17 00:00 [received] -PHST- 2012/09/25 00:00 [revised] -PHST- 2012/11/02 00:00 [accepted] -PHST- 2013/01/09 06:00 [entrez] -PHST- 2013/01/09 06:00 [pubmed] -PHST- 2013/08/29 06:00 [medline] -AID - S1465-3249(12)00032-1 [pii] -AID - 10.1016/j.jcyt.2012.11.003 [doi] -PST - ppublish -SO - Cytotherapy. 2013 Apr;15(4):399-415. doi: 10.1016/j.jcyt.2012.11.003. Epub 2013 - Jan 5. - -PMID- 22258902 -OWN - NLM -STAT- MEDLINE -DCOM- 20120313 -LR - 20120119 -IS - 1524-4636 (Electronic) -IS - 1079-5642 (Linking) -VI - 32 -IP - 2 -DP - 2012 Feb -TI - Recent studies of the human chromosome 9p21 locus, which is associated with - atherosclerosis in human populations. -PG - 196-206 -LID - 10.1161/ATVBAHA.111.232678 [doi] -AB - The chromosome 9p21 (Chr9p21) locus was discovered in 2007 by independent - genome-wide association studies for coronary artery disease. Since then, the - locus has been replicated numerous times and can be considered the most robust - genetic marker of coronary artery disease today. Subsequent work has shown - associations of Chr9p21 with a number of additional cardiovascular disease - traits, such as carotid artery plaque, stroke, aneurysms, peripheral artery - disease, heart failure, and cardiovascular mortality, suggesting a more general - role in vascular pathology. Importantly, Chr9p21 lacks associations with common - cardiovascular risk factors, such as lipids and hypertension, indicating that the - locus exerts its effect through a completely novel mechanism. One of the - challenges is that the core haplotype block at Chr9p21 resides in a region of the - genome devoid of protein-coding genes. Recent progress has been made by - functional studies focusing on differential expression of antisense noncoding RNA - in the INK4 locus (ANRIL), which is transcribed from the Chr9p21 locus, as well - as neighboring protein-coding genes at the INK4/ARF locus. The emerging concept - suggests that ANRIL might constitute a regulator of epigenetic modification and - thus modulate cardiovascular risk. Here, we review the current clinical, - mechanistic, and diagnostic implications of the Chr9p21 locus in cardiovascular - disease. -FAU - Holdt, Lesca M -AU - Holdt LM -AD - Institute of Laboratory Medicine, Ludwig-Maximilians-University Munich, Munich, - Germany. -FAU - Teupser, Daniel -AU - Teupser D -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Arterioscler Thromb Vasc Biol -JT - Arteriosclerosis, thrombosis, and vascular biology -JID - 9505803 -RN - 0 (Cyclin-Dependent Kinase Inhibitor p16) -RN - 0 (Tumor Suppressor Protein p14ARF) -SB - IM -MH - Atherosclerosis/*genetics -MH - Cardiovascular Diseases/genetics -MH - Chromosomes, Human, Pair 9/*genetics -MH - Cyclin-Dependent Kinase Inhibitor p16/genetics -MH - Genetic Loci/*genetics -MH - Genome-Wide Association Study -MH - Humans -MH - Tumor Suppressor Protein p14ARF/genetics -EDAT- 2012/01/20 06:00 -MHDA- 2012/03/14 06:00 -CRDT- 2012/01/20 06:00 -PHST- 2012/01/20 06:00 [entrez] -PHST- 2012/01/20 06:00 [pubmed] -PHST- 2012/03/14 06:00 [medline] -AID - 32/2/196 [pii] -AID - 10.1161/ATVBAHA.111.232678 [doi] -PST - ppublish -SO - Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):196-206. doi: - 10.1161/ATVBAHA.111.232678. - -PMID- 24057770 -OWN - NLM -STAT- MEDLINE -DCOM- 20140519 -LR - 20211021 -IS - 1534-3170 (Electronic) -IS - 1523-3782 (Linking) -VI - 15 -IP - 11 -DP - 2013 Nov -TI - Exercise: friend or foe in adult congenital heart disease? -PG - 416 -LID - 10.1007/s11886-013-0416-9 [doi] -AB - Exercise training is beneficial in healthy adults as well as patients with - acquired cardiovascular disease such as coronary artery disease and heart - failure. While a reduced exercise capacity is common in adults with congenital - heart disease, it is not clear if these patients stand to benefit from exercise - training or if it could be potentially detrimental. International recommendations - encourage regular exercise in these patients but the evidence base is limited. - Data from cardiopulmonary exercise testing suggest a relatively low risk of - adverse events during exercise in adults with congenital heart disease. This is - also supported by studies investigating the mode of death in this patient group, - reporting that only a minority of patients die during exercise. Regarding the - benefits of exercise training in adults with congenital heart disease only a few - studies with relatively small sample sizes are available pointing to beneficial - effects in selected patients. Encouragingly, in none of these short-term studies - were detrimental effects observed. Therefore, adult congenital heart disease - patients should not be categorically discouraged from physical activity or from - participating in non-competitive sports. However, individual exercise - prescriptions should be based on a comprehensive assessment of the underlying - cardiac condition, possible sequelae, cardiac function, arrhythmias, pulmonary - hypertension, and aortic dimensions. Furthermore, the intensity of exercise - should be adapted to individual exercise capacity. -FAU - Tutarel, Oktay -AU - Tutarel O -AD - Department of Cardiology & Angiology, Hannover Medical School, Carl-Neuberg-Str. - 1, 30625, Hannover, Germany, otutarel@hotmail.com. -FAU - Gabriel, Harald -AU - Gabriel H -FAU - Diller, Gerhard-Paul -AU - Diller GP -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -SB - IM -MH - Adult -MH - Evidence-Based Medicine -MH - *Exercise -MH - Exercise Test -MH - Exercise Therapy/*adverse effects/methods -MH - Exercise Tolerance -MH - Female -MH - Heart Defects, Congenital/mortality/physiopathology/*therapy -MH - Humans -MH - Male -MH - Patient Education as Topic -MH - Patient Selection -MH - Practice Guidelines as Topic -MH - Risk Factors -EDAT- 2013/09/24 06:00 -MHDA- 2014/05/20 06:00 -CRDT- 2013/09/24 06:00 -PHST- 2013/09/24 06:00 [entrez] -PHST- 2013/09/24 06:00 [pubmed] -PHST- 2014/05/20 06:00 [medline] -AID - 10.1007/s11886-013-0416-9 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2013 Nov;15(11):416. doi: 10.1007/s11886-013-0416-9. - -PMID- 18086002 -OWN - NLM -STAT- MEDLINE -DCOM- 20080226 -LR - 20081121 -IS - 1462-2416 (Print) -IS - 1462-2416 (Linking) -VI - 8 -IP - 12 -DP - 2007 Dec -TI - Endothelial nitric oxide synthase gene: prospects for treatment of heart disease. -PG - 1723-34 -AB - Nitric oxide functions as a signaling molecule with a well-established role in - vascular homeostasis. It is synthesized from the oxidation of L-arginine by the - enzyme, endothelial nitric oxide synthase (eNOS). The eNOS gene has a number of - polymorphic sites, including SNPs, dinucleotide repeats and variable number - tandem repeat sequences, and the opportunity exists to investigate polymorphic - functional correlates as well as disease-specific associations, especially in - cardiovascular disease, including coronary artery disease, and its most severe - consequence, myocardial infarction. A number of clinical and functional - correlative studies involving eNOS polymorphisms have been reported and are - presented. The promise and complexity of pharmacogenetics is illustrated using - eNOS as an example because of its relationship with cardiovascular biology and - pathology. In this review, we will discuss the impact of nitric oxide, eNOS, - genetic regulation, clinical investigation and, ultimately, prospects for - treatment of heart disease. -FAU - Cooke, Glen E -AU - Cooke GE -AD - The Ohio State University, Division of Cardiovascular Medicine and Davis Heart - and Lung Research Institute, Department of Medicine, 235 DHLRI, 473 W 12th - Avenue, Columbus, Ohio 43210-1252, USA. glen.cooke@osumc.edu -FAU - Doshi, Amit -AU - Doshi A -FAU - Binkley, Philip F -AU - Binkley PF -LA - eng -GR - K23 HL004483/HL/NHLBI NIH HHS/United States -GR - K24 HL004483/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Pharmacogenomics -JT - Pharmacogenomics -JID - 100897350 -RN - EC 1.14.13.39 (Nitric Oxide Synthase Type III) -SB - IM -MH - Animals -MH - Exons -MH - Haplotypes -MH - Heart Diseases/enzymology/genetics/*therapy -MH - Humans -MH - Introns -MH - Nitric Oxide Synthase Type III/*genetics -MH - Pharmacogenetics -MH - Polymorphism, Single Nucleotide -MH - Promoter Regions, Genetic -RF - 99 -EDAT- 2007/12/19 09:00 -MHDA- 2008/02/27 09:00 -CRDT- 2007/12/19 09:00 -PHST- 2007/12/19 09:00 [pubmed] -PHST- 2008/02/27 09:00 [medline] -PHST- 2007/12/19 09:00 [entrez] -AID - 10.2217/14622416.8.12.1723 [doi] -PST - ppublish -SO - Pharmacogenomics. 2007 Dec;8(12):1723-34. doi: 10.2217/14622416.8.12.1723. - -PMID- 17009574 -OWN - NLM -STAT- MEDLINE -DCOM- 20061222 -LR - 20240718 -IS - 0160-9289 (Print) -IS - 1932-8737 (Electronic) -IS - 0160-9289 (Linking) -VI - 29 -IP - 9 Suppl 1 -DP - 2006 Sep -TI - Clinical utility of contrast-enhanced echocardiography. -PG - I15-25 -AB - Over the past three decades, echocardiography has become a major diagnostic tool - in the arsenal of clinical cardiology for real-time imaging of cardiac dynamics. - More and more, cardiologists' decisions are based on images created from - ultrasound wave reflections. From the time ultrasound imaging technology provided - the first insight into a human heart, our diagnostic capabilities have increased - exponentially as a result of our growing knowledge and developing technologies. - One of the most intriguing developments that brought about a decade-long - combination of expectations and disappointments was the introduction of - echocardiographic contrast agents. Despite repeated waves of controversy - regarding the readiness of this technology for clinical use, it has overcome - multiple hurdles and currently provides useful clinical information that helps - cardiologists to diagnose heart disease accurately. Since the initial reports on - the use of ultrasound contrast media such as agitated saline or renografin, the - major advances in the field of contrast echocardiography have included (1) the - development of stable perfluorocarbon-filled microbubbles, frequently referred to - as second-generation contrast agents; and (2) the development of - contrast-targeted nonlinear imaging modes, such as harmonic imaging, pulse - inversion, and power modulation, which allow consistent real-time visualization - of these agents. These contrast agents in conjunction with the new imaging - technology constitute powerful tools that improve our ability to evaluate left - ventricular function and myocardial perfusion, and allow differential diagnosis - of thrombi and intravascular masses. In this manuscript, we briefly review some - of the literature that has provided the scientific basis for the use of - echocardiographic contrast agents in the context of these important variables. -FAU - Lang, Roberto M -AU - Lang RM -AD - Cardiac Imaging Center, Department of Medicine, University of Chicago Medical - Center, Illinois, USA. rlang@medicine.bsd.uchicago.edu -FAU - Mor-Avi, Victor -AU - Mor-Avi V -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Cardiol -JT - Clinical cardiology -JID - 7903272 -RN - 0 (Contrast Media) -SB - IM -MH - *Contrast Media -MH - Coronary Vessels/diagnostic imaging -MH - *Echocardiography/methods -MH - Heart Diseases/*diagnosis -MH - Humans -MH - Imaging, Three-Dimensional/methods -PMC - PMC6654323 -EDAT- 2006/10/03 09:00 -MHDA- 2006/12/23 09:00 -PMCR- 2009/08/18 -CRDT- 2006/10/03 09:00 -PHST- 2006/10/03 09:00 [pubmed] -PHST- 2006/12/23 09:00 [medline] -PHST- 2006/10/03 09:00 [entrez] -PHST- 2009/08/18 00:00 [pmc-release] -AID - CLC4960291304 [pii] -AID - 10.1002/clc.4960291304 [doi] -PST - ppublish -SO - Clin Cardiol. 2006 Sep;29(9 Suppl 1):I15-25. doi: 10.1002/clc.4960291304. - -PMID- 24331936 -OWN - NLM -STAT- MEDLINE -DCOM- 20140805 -LR - 20161128 -IS - 1876-861X (Electronic) -IS - 1876-861X (Linking) -VI - 7 -IP - 6 -DP - 2013 Nov-Dec -TI - Cardiovascular manifestations of Williams syndrome: imaging findings. -PG - 400-7 -LID - S1934-5925(13)00478-4 [pii] -LID - 10.1016/j.jcct.2013.11.007 [doi] -AB - Williams syndrome is a relatively common (1 in 10,000 live births) genetic - disorder caused by a deletion involving chromosome 7 that results in a variety of - clinically significant abnormalities, including developmental delay, behavioral - changes, hypercalcemia, and a distinct "elfin" facial appearance. Congenital - cardiovascular disease that presents in childhood is responsible for most of the - morbidity and mortality associated with this disorder. The purpose of this - pictorial essay is to review imaging findings of some of the more common - cardiovascular manifestations of Williams syndrome and to highlight some of the - unique anatomic variations that can be seen in these patients. -CI - Copyright © 2013 Society of Cardiovascular Computed Tomography. Published by - Elsevier Inc. All rights reserved. -FAU - Gray, J Cranston 3rd -AU - Gray JC 3rd -AD - Department of Radiology and Radiological Science, Medical University of South - Carolina, 25 Courtenay Dr, Charleston, SC 29425, USA. -FAU - Krazinski, Aleksander W -AU - Krazinski AW -AD - Department of Radiology and Radiological Science, Medical University of South - Carolina, 25 Courtenay Dr, Charleston, SC 29425, USA. -FAU - Schoepf, U Joseph -AU - Schoepf UJ -AD - Department of Radiology and Radiological Science, Medical University of South - Carolina, 25 Courtenay Dr, Charleston, SC 29425, USA. Electronic address: - schoepf@musc.edu. -FAU - Meinel, Felix G -AU - Meinel FG -AD - Department of Radiology and Radiological Science, Medical University of South - Carolina, 25 Courtenay Dr, Charleston, SC 29425, USA; Institute for Clinical - Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany. -FAU - Pietris, Nicholas P -AU - Pietris NP -AD - Division of Pediatric Cardiology, Department of Pediatrics, Medical University of - South Carolina, Charleston, SC, USA. -FAU - Suranyi, Pal -AU - Suranyi P -AD - Department of Radiology and Radiological Science, Medical University of South - Carolina, 25 Courtenay Dr, Charleston, SC 29425, USA. -FAU - Hlavacek, Anthony M -AU - Hlavacek AM -AD - Department of Radiology and Radiological Science, Medical University of South - Carolina, 25 Courtenay Dr, Charleston, SC 29425, USA; Division of Pediatric - Cardiology, Department of Pediatrics, Medical University of South Carolina, - Charleston, SC, USA. -LA - eng -PT - Journal Article -PT - Review -DEP - 20131107 -PL - United States -TA - J Cardiovasc Comput Tomogr -JT - Journal of cardiovascular computed tomography -JID - 101308347 -SB - IM -MH - Child -MH - Child, Preschool -MH - Coronary Angiography/*methods -MH - Female -MH - Heart Defects, Congenital/*diagnostic imaging -MH - Humans -MH - Infant -MH - Male -MH - Tomography, X-Ray Computed/*methods -MH - Williams Syndrome/*diagnostic imaging -OTO - NOTNLM -OT - Cardiovascular CT angiography -OT - Pediatric cardiothoracic surgery -OT - Pulmonary artery stenosis -OT - Supravalvular aortic stenosis -OT - Williams syndrome -EDAT- 2013/12/18 06:00 -MHDA- 2014/08/06 06:00 -CRDT- 2013/12/17 06:00 -PHST- 2013/08/01 00:00 [received] -PHST- 2013/10/21 00:00 [revised] -PHST- 2013/11/04 00:00 [accepted] -PHST- 2013/12/17 06:00 [entrez] -PHST- 2013/12/18 06:00 [pubmed] -PHST- 2014/08/06 06:00 [medline] -AID - S1934-5925(13)00478-4 [pii] -AID - 10.1016/j.jcct.2013.11.007 [doi] -PST - ppublish -SO - J Cardiovasc Comput Tomogr. 2013 Nov-Dec;7(6):400-7. doi: - 10.1016/j.jcct.2013.11.007. Epub 2013 Nov 7. - -PMID- 22141305 -OWN - NLM -STAT- MEDLINE -DCOM- 20120126 -LR - 20111206 -IS - 1660-9379 (Print) -IS - 1660-9379 (Linking) -VI - 7 -IP - 314 -DP - 2011 Oct 26 -TI - [Maternal heart disease and pregnancy: a multidisciplinary approach]. -PG - 2070, 2072-4, 2076-7 -AB - In developed countries, cardiovascular diseases are becoming one of the first - causes of maternal death. Myocardial infarction, dissection of the thoracic aorta - and cardiomyopathies are the leading causes. However, preexisting maternal - cardiac diseases, such as congenital heart diseases, are more commonly - encountered and may be associated with significant maternal and perinatal - morbidity. This article reviews hemodynamic changes occurring during pregnancy, - proposes a risk stratification according to pre-existing cardiac diseases, and - discusses the monitoring and overall management of these patients. Finally, two - pregnancy-triggered cardiac diseases are discussed: coronary artery disease and - peripartum cardiomyopathy. -FAU - Jastrow, N -AU - Jastrow N -AD - Service d'obstétrique, Département de gynécologie et obstétrique, HUG, 1211 - Genève. Nicole.JastrowMeyer@huge.ch -FAU - Meyer, P -AU - Meyer P -FAU - Bouchardy, J -AU - Bouchardy J -FAU - Savoldelli, G L -AU - Savoldelli GL -FAU - Irion, O -AU - Irion O -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Cardiopathies maternelles et grossesse: une prise en charge multidisciplinaire. -PL - Switzerland -TA - Rev Med Suisse -JT - Revue medicale suisse -JID - 101219148 -SB - IM -MH - Blood Pressure/physiology -MH - Female -MH - Humans -MH - *Patient Care Team -MH - Pregnancy/*physiology -MH - Pregnancy Complications, Cardiovascular/physiopathology/*therapy -MH - *Risk Assessment -MH - Stroke Volume/physiology -EDAT- 2011/12/07 06:00 -MHDA- 2012/01/27 06:00 -CRDT- 2011/12/07 06:00 -PHST- 2011/12/07 06:00 [entrez] -PHST- 2011/12/07 06:00 [pubmed] -PHST- 2012/01/27 06:00 [medline] -PST - ppublish -SO - Rev Med Suisse. 2011 Oct 26;7(314):2070, 2072-4, 2076-7. - -PMID- 20447526 -OWN - NLM -STAT- MEDLINE -DCOM- 20100610 -LR - 20220309 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 55 -IP - 19 -DP - 2010 May 11 -TI - Natriuretic peptides in common valvular heart disease. -PG - 2034-48 -LID - 10.1016/j.jacc.2010.02.021 [doi] -AB - Valvular heart disease, particularly aortic stenosis and mitral regurgitation, - accounts for a large proportion of cardiology practice, and their prevalence is - predicted to increase. Management of the asymptomatic patient remains - controversial. Biomarkers have been shown to have utility in the management of - cardiovascular disease such as heart failure and acute coronary syndromes. In - this state-of-the-art review, we examine the current evidence relating to - natriuretic peptides as potential biomarkers in aortic stenosis and mitral - regurgitation. The natriuretic peptides correlate with measures of disease - severity and symptomatic status and also can be used to predict outcome. This - review shows that natriuretic peptides have much promise as biomarkers in common - valvular heart disease, but the impact of their measurement on clinical practice - and outcomes needs to be further assessed in prospective studies before routine - clinical use becomes a reality. -CI - Copyright 2010 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Steadman, Christopher D -AU - Steadman CD -AD - Department of Cardiovascular Sciences, University Hospitals of Leicester, - Leicester, UK. cds18@le.ac.uk -FAU - Ray, Simon -AU - Ray S -FAU - Ng, Leong L -AU - Ng LL -FAU - McCann, Gerry P -AU - McCann GP -LA - eng -GR - 07/068/2334/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Biomarkers) -RN - 0 (Natriuretic Peptides) -SB - IM -MH - Aortic Valve Stenosis/diagnosis/etiology/*metabolism -MH - Biomarkers/*metabolism -MH - Humans -MH - Mitral Valve Insufficiency/diagnosis/etiology/*metabolism -MH - Natriuretic Peptides/*physiology -MH - Predictive Value of Tests -MH - Prognosis -MH - Severity of Illness Index -RF - 95 -EDAT- 2010/05/08 06:00 -MHDA- 2010/06/11 06:00 -CRDT- 2010/05/08 06:00 -PHST- 2009/09/14 00:00 [received] -PHST- 2010/01/19 00:00 [revised] -PHST- 2010/02/09 00:00 [accepted] -PHST- 2010/05/08 06:00 [entrez] -PHST- 2010/05/08 06:00 [pubmed] -PHST- 2010/06/11 06:00 [medline] -AID - S0735-1097(10)00899-5 [pii] -AID - 10.1016/j.jacc.2010.02.021 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2010 May 11;55(19):2034-48. doi: 10.1016/j.jacc.2010.02.021. - -PMID- 17413278 -OWN - NLM -STAT- MEDLINE -DCOM- 20070911 -LR - 20071115 -IS - 0268-4705 (Print) -IS - 0268-4705 (Linking) -VI - 22 -IP - 3 -DP - 2007 May -TI - The contribution of familial and heritable risks in heart failure. -PG - 214-9 -AB - PURPOSE OF REVIEW: The purpose of this review is to summarize the recent - literature regarding the familial heritability of heart failure and to discuss - the possible mechanisms through which this risk is mediated. RECENT FINDINGS: - Data from the Framingham Heart Study recently showed that the parental occurrence - of heart failure increases the risk of heart failure in offspring. Although the - mechanisms mediating this increased risk are not elucidated, heritable risks of - heart failure may result from genes affecting the cardiac or vascular systems. - Alternatively, familial risk may be mediated partly through the inheritance of - recognized or as yet unidentified risk factors for heart failure. Heritable - components or genetic loci for quantitative traits contribute to the development - of hypertension, coronary artery disease, cardiomyopathies, valvular heart - disease, and metabolic conditions, which collectively increase the risk of heart - failure. SUMMARY: A careful assessment of the family history of heart failure and - associated risk factors may identify treatable targets that can potentially - reduce the likelihood of developing heart failure, and can assist in the - implementation of preventive strategies for risk populations with stages A and B - heart failure. -FAU - Abdel-Qadir, Husam M -AU - Abdel-Qadir HM -AD - Faculty of Medicine, University Health Network, University of Toronto, Toronto, - Canada. -FAU - Lee, Douglas S -AU - Lee DS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -SB - IM -MH - *Genetic Diseases, Inborn -MH - Genetic Predisposition to Disease -MH - Genotype -MH - Heart Failure/*genetics/prevention & control -MH - Humans -MH - Insulin Resistance -MH - Obesity -MH - Phenotype -MH - Risk Assessment -MH - Risk Factors -RF - 93 -EDAT- 2007/04/07 09:00 -MHDA- 2007/09/12 09:00 -CRDT- 2007/04/07 09:00 -PHST- 2007/04/07 09:00 [pubmed] -PHST- 2007/09/12 09:00 [medline] -PHST- 2007/04/07 09:00 [entrez] -AID - 00001573-200705000-00009 [pii] -AID - 10.1097/HCO.0b013e3280d9e855 [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2007 May;22(3):214-9. doi: 10.1097/HCO.0b013e3280d9e855. - -PMID- 20376643 -OWN - NLM -STAT- MEDLINE -DCOM- 20100715 -LR - 20211020 -IS - 1615-6692 (Electronic) -IS - 0340-9937 (Linking) -VI - 35 -IP - 2 -DP - 2010 Mar -TI - [Treatment of progressive heart failure: pharmacotherapy, resynchronization - (CRT), surgery]. -PG - 94-101 -LID - 10.1007/s00059-010-3329-z [doi] -AB - The treatment of progressive and terminal heart failure follows the principle of - causative therapy. Therefore, etiology and pathophysiology of the underlying - disease and its hemodynamic conditions are indispensable. This applies to - coronary artery disease, hypertension, valvular heart disease, the - cardiomyopathies with and without inflammation, and microbial persistence - similarly. The classic treatment algorithms both in heart failure with and - without reduced ejection fraction are based on measures onloading the heart - (angiotensin-converting enzyme inhibitors, angiotensin antagonists, - beta-blockers, diuretics) and on antiarrhythmics and anticoagulation, when - needed. Device therapy for cardiac resynchronization in left bundle branch block - and permanent stimulation therapy may contribute to the hemodynamic benefit. ICD - (implantable cardioverter defibrillator) therapy prevents sudden cardiac death, - which is often associated with progressive heart failure. Heart transplantation - and left ventricular assist devices are final options in the treatment repertoire - of terminal heart failure. -FAU - Maisch, Bernhard -AU - Maisch B -AD - Klinik für Innere Medizin - Kardiologie, Philipps-Universität, Marburg und UKGM - GmbH, Standort Marburg, Marburg, Germany. maisch@staff.uni-marburg.de -FAU - Pankuweit, Sabine -AU - Pankuweit S -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Therapie der fortgeschrittenen Herz - insuffizienz: medikamentös, - Resynchronisation (CRT), Operation. -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Biopsy -MH - Cardiac Output, Low/diagnosis/etiology/therapy -MH - Cardiovascular Agents/*therapeutic use -MH - *Defibrillators, Implantable -MH - Evidence-Based Medicine -MH - Heart Failure/diagnosis/etiology/*therapy -MH - *Heart Transplantation -MH - *Heart-Assist Devices -MH - Humans -MH - Myocarditis/complications/diagnosis/pathology/therapy -MH - Myocardium/pathology -MH - Prognosis -MH - Randomized Controlled Trials as Topic -RF - 71 -EDAT- 2010/04/09 06:00 -MHDA- 2010/07/16 06:00 -CRDT- 2010/04/09 06:00 -PHST- 2010/04/09 06:00 [entrez] -PHST- 2010/04/09 06:00 [pubmed] -PHST- 2010/07/16 06:00 [medline] -AID - 10.1007/s00059-010-3329-z [doi] -PST - ppublish -SO - Herz. 2010 Mar;35(2):94-101. doi: 10.1007/s00059-010-3329-z. - -PMID- 21704394 -OWN - NLM -STAT- MEDLINE -DCOM- 20120810 -LR - 20220311 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 155 -IP - 2 -DP - 2012 Mar 8 -TI - Soluble epoxide hydrolase and ischemic cardiomyopathy. -PG - 181-7 -LID - 10.1016/j.ijcard.2011.05.067 [doi] -AB - BACKGROUND: The development of cardiovascular disease has been linked to lowered - levels of epoxyeicosatrienoic acids (EETs) in the cardiovascular system. Ischemic - cardiomyopathy is caused by atherosclerotic lesions in multi-coronary arteries - especially diffusive lesions, which can lead to severe myocardial dysfunction, - heart enlargement, heart failure, or arrhythmia, and so on. The EETs are - metabolized by the soluble epoxide hydrolase (sEH) encoded by the EPHX2 gene that - has several known polymorphisms. CONTENT: The EPHX2 gene polymorphism is - associated with sEH catalytic activity and various cardiovascular diseases. sEH - is distributed in a variety of organs and tissues and regulated by multiple - factors. Research in the area has led to the presence of multiple powerful - soluble epoxide hydrolase inhibitors (sEHIs), whose molecular structure and - function has been optimized gradually. sEHIs increase EETs' concentration by - inhibiting hydration of EETs into their corresponding vicinal diols. EETs are - important signaling molecules and known as endothelium-derived hyperpolarizing - factors (EDHF). sEHIs have been developed for their ability to prevent - atherosclerosis, dilate the coronary artery, promote angiogenesis, ameliorate - postischemic recovery of heart contractile function, decrease - ischemia/reperfusion injury, modulate postischemic arrhythmia, and prevent heart - failure. SUMMARY: sEH is one of the etiological factors of cardiovascular - diseases, and plays an important role in the progression of myocardium ischemia. - This indicates that sEHIs provide a new method for the prevention and treatment - of ischemic cardiomyopathy. -CI - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. -FAU - Zhao, Ting-Ting -AU - Zhao TT -AD - Department of Cardiovascular Internal Medicine, Second Xiangya Hospital, Central - South University Changsha, 410011, PR China. -FAU - Wasti, Binaya -AU - Wasti B -FAU - Xu, Dan-Yan -AU - Xu DY -FAU - Shen, Li -AU - Shen L -FAU - Du, Jian-Qing -AU - Du JQ -FAU - Zhao, Shui-Ping -AU - Zhao SP -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110624 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - EC 3.3.2.- (Epoxide Hydrolases) -RN - EC 3.3.2.10 (EPHX2 protein, human) -SB - IM -MH - Cardiomyopathies/*genetics/*metabolism/physiopathology -MH - Epoxide Hydrolases/*genetics/*metabolism -MH - Humans -MH - Myocardial Ischemia/*genetics/*metabolism/physiopathology -MH - Polymorphism, Genetic -MH - Solubility -EDAT- 2011/06/28 06:00 -MHDA- 2012/08/11 06:00 -CRDT- 2011/06/28 06:00 -PHST- 2010/11/26 00:00 [received] -PHST- 2011/03/08 00:00 [revised] -PHST- 2011/05/13 00:00 [accepted] -PHST- 2011/06/28 06:00 [entrez] -PHST- 2011/06/28 06:00 [pubmed] -PHST- 2012/08/11 06:00 [medline] -AID - S0167-5273(11)00480-3 [pii] -AID - 10.1016/j.ijcard.2011.05.067 [doi] -PST - ppublish -SO - Int J Cardiol. 2012 Mar 8;155(2):181-7. doi: 10.1016/j.ijcard.2011.05.067. Epub - 2011 Jun 24. - -PMID- 22825343 -OWN - NLM -STAT- MEDLINE -DCOM- 20121025 -LR - 20120724 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 13 -IP - 9 -DP - 2012 Sep -TI - [Cardiac arrest management: any news? When the literature does not meet clinical - practice]. -PG - 583-91 -LID - 10.1714/1133.12486 [doi] -AB - The percentage of patients transported alive to hospital after an out-of-hospital - cardiac arrest has increased in recent years thanks to growing population - education. In 2010 the International Liaison Committee on Resuscitation (ILCOR) - has published new guidelines for the management of cardiac arrest. These - guidelines present several new features, but cardiac compression remains the - mainstay of optimal cardiopulmonary resuscitation. Use of atropine and - endotracheal drugs are no longer recommended, and early ultrasound evaluation and - intraosseous vascular access are new methods now standardized. The best chances - of improving patient prognosis are in the period immediately after return of - spontaneous circulation (ROSC). It is well known that most patients who - experience cardiac arrest without an obvious extra-cardiac cause, show - significant underlying coronary artery disease. Hence, the importance of - widespread and early use of primary percutaneous coronary intervention. An early - percutaneous coronary intervention was found to be crucial not only in increasing - survival, but also in improving neurological outcome at discharge. The ILCOR - consensus statement suggests that therapeutic hypothermia should be considered as - the standard treatment for comatose patients resuscitated from cardiac arrest. - This was supported by the evidence that moderate hypothermia is the only - treatment for post-ROSC as it is associated with a significant increase in - survival. For this reason, it should be started as early as possible, preferably - in the pre-hospital setting. Despite the bulk of available literature on the - early treatment of cardiac arrest, the studies carried out in Italy indicate that - most post-ROSC patients are undertreated or untreated. This results in poor - resource utilization with a high social and personal impact that involves both - the patients and their families. Teamwork activities addressing the chain of - survival become a fundamental tool for the treatment of resuscitated patients. - Given the crucial importance of the time elapsing from collapse to - cardiopulmonary resuscitation in terms of final prognosis, efforts should be made - to promote the "culture of cardiopulmonary resuscitation" not only among health - professionals, but also among the general population. -FAU - Grieco, Niccolò -AU - Grieco N -AD - AAT 118 Milano AREU Lombardia, A.O. Ospedale Niguarda Ca' Granda, 20162 Milano, - Italy. niccolo.grieco@118milano.it -FAU - Manzoni, Paola -AU - Manzoni P -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - Quali novità nella gestione dell'arresto cardiaco. Quando la letteratura non - incontra la pratica clinica. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -SB - IM -MH - Cardiopulmonary Resuscitation -MH - Heart Arrest/*therapy -MH - Humans -MH - Hypothermia, Induced -MH - Practice Guidelines as Topic -EDAT- 2012/07/25 06:00 -MHDA- 2012/10/26 06:00 -CRDT- 2012/07/25 06:00 -PHST- 2012/07/25 06:00 [entrez] -PHST- 2012/07/25 06:00 [pubmed] -PHST- 2012/10/26 06:00 [medline] -AID - 10.1714/1133.12486 [doi] -PST - ppublish -SO - G Ital Cardiol (Rome). 2012 Sep;13(9):583-91. doi: 10.1714/1133.12486. - -PMID- 17258118 -OWN - NLM -STAT- MEDLINE -DCOM- 20070323 -LR - 20070129 -IS - 0889-8588 (Print) -IS - 0889-8588 (Linking) -VI - 21 -IP - 1 -DP - 2007 Feb -TI - Platelet inhibitors and monitoring platelet function: implications for bleeding. -PG - 51-63 -AB - Cardiovascular disease is prevalent in our medical and surgical. Patients who - have atherosclerotic heart disease suffer from endothelial disorders that - predispose them to plaque and thrombus formation in diseased arteries. As our - knowledge of platelet physiology improves, we can understand the contribution of - platelet activation to arterial disease and we can specifically inhibit that - activation with platelet-inhibitory drugs. The recent increase in the number of - coronary interventional procedures performed has spawned the increasing use of - antiplatelet medication as prophylaxis against thrombus formation in the - instrumented artery. -FAU - Shore-Lesserson, Linda -AU - Shore-Lesserson L -AD - Department of Anesthesiology, Cardiothoracic Anesthesiology, Montefiore Medical - Center, 111 East 210th Street, Bronx, NY 10467, USA. lshore@montefiore.org -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Hematol Oncol Clin North Am -JT - Hematology/oncology clinics of North America -JID - 8709473 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Animals -MH - Blood Platelets/drug effects/*physiology -MH - Drug Monitoring/methods -MH - *Hemorrhage/drug therapy -MH - Hemostasis/drug effects/physiology -MH - Humans -MH - *Platelet Aggregation Inhibitors/pharmacology/therapeutic use -MH - Thrombelastography/methods -RF - 45 -EDAT- 2007/01/30 09:00 -MHDA- 2007/03/24 09:00 -CRDT- 2007/01/30 09:00 -PHST- 2007/01/30 09:00 [pubmed] -PHST- 2007/03/24 09:00 [medline] -PHST- 2007/01/30 09:00 [entrez] -AID - S0889-8588(06)00197-3 [pii] -AID - 10.1016/j.hoc.2006.11.012 [doi] -PST - ppublish -SO - Hematol Oncol Clin North Am. 2007 Feb;21(1):51-63. doi: - 10.1016/j.hoc.2006.11.012. - -PMID- 17020679 -OWN - NLM -STAT- MEDLINE -DCOM- 20061212 -LR - 20191026 -IS - 0210-5705 (Print) -IS - 0210-5705 (Linking) -VI - 29 -IP - 8 -DP - 2006 Oct -TI - [Approach to thoracic pain from the gastroenterologist's point of view]. -PG - 455-62 -AB - Chest pain is common in medical consultations. One of the most frequent and - serious causes is acute ischemic heart disease, which must be ruled out. The gold - standard is coronary angiography. Noncardiac recurrent chest pain has a favorable - prognosis. The most frequent cause is esophageal disease, with a prevalence of - between 20% and 50%. The most frequent form is gastroesophageal reflux disease - followed by esophageal motor disorders. Empirical treatment with high-dose proton - pump inhibitors should be considered as a diagnostic-therapeutic test before - performing exhaustive complementary investigations of esophageal function. Among - complementary tests, manometry combined with 24-hour pH-metry has the highest - diagnostic yield. Antidepressants are an acceptable therapeutic option in - patients with esophageal visceral hyperalgesia. -FAU - Ortiz Bellver, V -AU - Ortiz Bellver V -AD - Servicio de Medicina Digestiva, Hospital Universitario La Fe, Avda. Campanar 21, - 46009 Valencia, Spain. -FAU - Garrigues Gil, V -AU - Garrigues Gil V -LA - spa -PT - English Abstract -PT - Journal Article -PT - Review -TT - Aproximación al dolor torácico desde el punto de vista del digestólogo. -PL - Spain -TA - Gastroenterol Hepatol -JT - Gastroenterologia y hepatologia -JID - 8406671 -SB - IM -MH - Chest Pain/diagnosis/*etiology -MH - Diagnosis, Differential -MH - Esophageal Diseases/*complications/diagnosis -MH - Humans -RF - 40 -EDAT- 2006/10/06 09:00 -MHDA- 2006/12/13 09:00 -CRDT- 2006/10/06 09:00 -PHST- 2006/10/06 09:00 [pubmed] -PHST- 2006/12/13 09:00 [medline] -PHST- 2006/10/06 09:00 [entrez] -AID - 13092565 [pii] -AID - 10.1157/13092565 [doi] -PST - ppublish -SO - Gastroenterol Hepatol. 2006 Oct;29(8):455-62. doi: 10.1157/13092565. - -PMID- 21088655 -OWN - NLM -STAT- MEDLINE -DCOM- 20110121 -LR - 20191111 -IS - 1947-6094 (Print) -IS - 1947-6108 (Linking) -VI - 6 -IP - 4 -DP - 2010 Nov-2011 Jan -TI - Where do we currently stand with advice on hormone replacement therapy for women? -PG - 21-5 -LID - 1947-6108-6-4-21 [pii] -AB - Nearly 250,000 women die each year from cardiovascular disease, making it the - leading cause of death in women. The initial clinical manifestation of coronary - artery disease (CAD) in women is usually 10 years later than in men on average, - with the first myocardial infarction presenting 20 years later. At any age the - prevalence of CAD is lower in women, but with advancing age, this gender - differential diminishes. The fact that CAD prevalence is lower in women has led - to the false presumption that women are protected from cardiovascular diseases. - Since women live 8 to 10 years longer than men, the absolute number of deaths - from cardiovascular disease (CVD) exceeds that of men. Although there has been a - decline in the overall number of cardiovascular deaths, the coronary incidence - has been increasing in women and decreasing in men. Contrary to belief, CAD - causes far more deaths in women than does cancer (Figure 1). Consider the - statistics: approximately 1 out of 3 women will die of a cardiovascular event; - more than a half-million women die of CVD each year; one women dies of CVD almost - each minute in the United States; and two-thirds of the women who die suddenly - have no previously recognized symptoms. Advances in diagnosis and treatment of - CVD appear to have translated into a survival benefit in men but not in women. - The mortality due to CVD remains high in women, with no improvement in survival - trends over time compared to men (Figure 2). This may be related to differences - and delays in recognizing CVD in women or in treatment strategies, and to - biological differences. Women with acute coronary syndrome often delay calling - for professional help and present more frequently with atypical symptoms, such as - abnormal pain locations, nausea, vomiting, fatigue, and dyspnea. Women not only - present later from the onset of chest pain but are also sicker at the time of - diagnosis. Furthermore, there appears to be a bias against heart disease in women - - both patients and their caregivers/health care providers do not recognize or - treat CVD in a timely manner in women. Compared to men, women are less likely to - receive appropriate treatment for heart disease such as optimal control of blood - pressure, use of aspirin, cholesterol-lowering medications, thrombolytics, or - referrals for interventions such as balloon/ stent or bypass surgery. Women seem - to be evaluated less intensively, and referrals for cardiac catheterization are - 8-fold higher in men than in women. The clinical outcomes including myocardial - infarction mortality, all-cause mortality, and reinfarction rates are worse in - women with CVD than in men. Many risk factors contribute to CAD in women, but - menopause is one of the strongest. Risk of CAD in postmenopausal women is 40 to - 50% higher than in premenopausal women, and hormone replacement therapy (HRT) - increases the risk. This paper discusses the myriad risk factors for CAD in women - and explores the relationship between CAD and hormone replacement therapy in - postmenopausal women. -FAU - Bozkurt, Biykem -AU - Bozkurt B -AD - Winters Center for Heart Failure Research at Baylor College of Medicine, Michael - E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA. -LA - eng -PT - Journal Article -PT - Portrait -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - United States -TA - Methodist Debakey Cardiovasc J -JT - Methodist DeBakey cardiovascular journal -JID - 101508600 -SB - IM -MH - Cardiovascular Diseases/etiology/mortality/*prevention & control -MH - *Estrogen Replacement Therapy/adverse effects -MH - Evidence-Based Medicine -MH - Female -MH - Health Status Disparities -MH - Healthcare Disparities -MH - Humans -MH - Male -MH - Practice Guidelines as Topic -MH - Preventive Health Services -MH - Risk Assessment -MH - Risk Factors -MH - Treatment Outcome -MH - *Women's Health -EDAT- 2010/11/23 06:00 -MHDA- 2011/01/22 06:00 -CRDT- 2010/11/20 06:00 -PHST- 2010/11/20 06:00 [entrez] -PHST- 2010/11/23 06:00 [pubmed] -PHST- 2011/01/22 06:00 [medline] -AID - 1947-6108-6-4-21 [pii] -AID - 10.14797/mdcj-6-4-21 [doi] -PST - ppublish -SO - Methodist Debakey Cardiovasc J. 2010 Nov-2011 Jan;6(4):21-5. doi: - 10.14797/mdcj-6-4-21. - -PMID- 20465100 -OWN - NLM -STAT- MEDLINE -DCOM- 20100601 -LR - 20100514 -IS - 0042-773X (Print) -IS - 0042-773X (Linking) -VI - 56 -IP - 4 -DP - 2010 Apr -TI - [Diabetes mellitus and ischemic heart disease]. -PG - 301-6 -AB - Diabetes mellitus (DM) is closely associated with cardiovascular (CV) diseases. - These are the main cause of death in patients not only with type 2 but also type - 1 diabetes. Apart from the traditional risk factors such as arterial - hypertension, dyslipidemia and obesity, hyperglycaemia is an independent risk - factor for the development of ischemic heart disease (IHD). Long-term - hyperglycaemia leads to vascular damage through several mechanisms. These include - oxidative stress, formation of advanced glycation end products, activation of the - nuclear factor kappa B and decreased production of nitrogen monoxide (NO). - Insulin resistance is believed to have an important bearing on pathogenesis of - IHD in type 2 diabetes (DM2) patients. The course of IHD in diabetic patients is - usually more complicated. Direct percutaneous coronary intervention (PCI) is the - gold standard in the treatment of myocardial infarction (MI) in diabetic as well - as non-diabetic patients. Drug-eluting stents, associated with fewer - reocclusions, have also proved useful. In addition to drug-eluting stent - implantation, surgical revascularization, preferably utilizing internal thoracic - artery, is a suitable technique in patients without acute coronary syndrome - indicated for an intervention. Conservative approach should be applied in less - severely affected patients. IHD prevention should include appropriate control of - arterial hypertension, dyslipidemia and weigh reduction. Diabetes treatment - should be managed individually and with respect to the potential risk of - hypoglycaemia in high-risk patients with longer duration of diabetes and known CV - disease. Newly diagnosed type 2 diabetes patients should from the onset be - treated with metformin and tight compensation should be aimed for with target - value for glycated haemoglobin of less than 4.5% (IFCC methodology). Evidence - exists that this approach may significantly reduce the CV risk. Intensified - insulin regimen is the most suitable treatment approach for the type 1 diabetes - patients also with respect to microvascular and macrovascular complication - prevention. Treatment of hyperglycaemia is one of the set of measures that may - contribute to CV risk reduction in diabetic patients. -FAU - Dresslerová, I -AU - Dresslerová I -AD - I. interní klinika Lékarské fakulty UK a FN Hradec Králové. dressirm@fnhk.cz -FAU - Vojácek, J -AU - Vojácek J -LA - cze -PT - English Abstract -PT - Journal Article -PT - Review -TT - Diabetes mellitus a ischemická choroba srdecní. -PL - Czech Republic -TA - Vnitr Lek -JT - Vnitrni lekarstvi -JID - 0413602 -SB - IM -MH - *Diabetes Complications/physiopathology -MH - Humans -MH - *Myocardial Ischemia/diagnosis/prevention & control/therapy -RF - 42 -EDAT- 2010/05/15 06:00 -MHDA- 2010/06/02 06:00 -CRDT- 2010/05/15 06:00 -PHST- 2010/05/15 06:00 [entrez] -PHST- 2010/05/15 06:00 [pubmed] -PHST- 2010/06/02 06:00 [medline] -PST - ppublish -SO - Vnitr Lek. 2010 Apr;56(4):301-6. - -PMID- 21525485 -OWN - NLM -STAT- MEDLINE -DCOM- 20110701 -LR - 20220317 -IS - 1935-5548 (Electronic) -IS - 0149-5992 (Print) -IS - 0149-5992 (Linking) -VI - 34 Suppl 2 -IP - Suppl 2 -DP - 2011 May -TI - Myocardial, perivascular, and epicardial fat. -PG - S371-9 -LID - 10.2337/dc11-s250 [doi] -AB - Myocardial fat content refers to the storage of triglyceride droplets within - cardiomyocytes. In addition, the heart and arteries are surrounded by layers of - adipose tissue, exerting vasocrine and paracrine control of the subtending - tissues. The rapid development of the field of noninvasive imaging has made it - possible to quantify ectopic fat masses and contents with an increasing degree of - accuracy. Myocardial triglyceride stores are increased in obesity, impaired - glucose tolerance, and type 2 diabetes. The role of intramyocardial triglyceride - accumulation in the pathogenesis of left ventricular (LV) dysfunction remains - unclear. Increased triglyceride content is associated with states of fatty acid - overload to the heart, saturating the oxidative capacity. It may initially serve - as a fatty acid sink to circumscribe the formation of toxic lipid species and - subsequently foster cardiac damage. Epicardial and perivascular fat depots may - exert a protective modulation of vascular function and energy partition in a - healthy situation, but their expansion turns them into an adverse lipotoxic, - prothrombotic, and proinflammatory organ. They are augmented in patients with - metabolic disorders and coronary artery disease (CAD). However, the progressive - association between the quantity of fat and disease severity in terms of extent - of plaque calcification or noncalcified areas, markers of plaque vulnerability, - and number of vessels involved is less confirmed. Functional or hybrid imaging - may contribute to a better definition of disease severity and unveil the direct - myocardial and vascular targets of adipose tissue action. -FAU - Iozzo, Patricia -AU - Iozzo P -AD - Institute of Clinical Physiology, National Research Council, Pisa, Italy. - patricia.iozzo@ifc.cnr.it -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Diabetes Care -JT - Diabetes care -JID - 7805975 -RN - 0 (Fats) -SB - IM -MH - Fats/*metabolism -MH - Heart Diseases/*metabolism -MH - Humans -MH - Myocardium/*metabolism -MH - Pericardium/*metabolism -PMC - PMC3632210 -EDAT- 2011/05/06 06:00 -MHDA- 2011/07/02 06:00 -PMCR- 2012/05/01 -CRDT- 2011/04/29 06:00 -PHST- 2011/04/29 06:00 [entrez] -PHST- 2011/05/06 06:00 [pubmed] -PHST- 2011/07/02 06:00 [medline] -PHST- 2012/05/01 00:00 [pmc-release] -AID - 34/Supplement_2/S371 [pii] -AID - S250 [pii] -AID - 10.2337/dc11-s250 [doi] -PST - ppublish -SO - Diabetes Care. 2011 May;34 Suppl 2(Suppl 2):S371-9. doi: 10.2337/dc11-s250. - -PMID- 19214303 -OWN - NLM -STAT- MEDLINE -DCOM- 20090327 -LR - 20220409 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Print) -IS - 0828-282X (Linking) -VI - 25 -IP - 2 -DP - 2009 Feb -TI - Coronary vein graft disease: pathogenesis and prevention. -PG - e57-62 -AB - Not long after coronary artery bypass grafting surgery was described, several - reports presented follow-up angiographic data on large cohorts of patients, - demonstrating that approximately one-half of saphenous vein grafts fail within 10 - to 15 years of surgery and that graft failure is associated with worse clinical - outcomes. Three processes are responsible for vein graft failure. Thrombosis, - intimal hyperplasia and accelerated atherosclerosis contribute to graft failure - in the acute, subacute and late postoperative periods, respectively. Studies have - shown that perioperative antiplatelet therapy can reduce early thrombosis and - graft failure. As in native coronaries, intensive lipid lowering can attenuate - the process of atherosclerosis in vein grafts. Intimal hyperplasia in the vein - graft is thought to be an adaptation of the vein to higher pressures in the - arterial circulation. This process is further promoted by the loss of inhibition - from the endothelial layer, which is injured during surgery. A new 'no-touch' - technique for harvesting grafts may be effective in preventing disruption to the - endothelial layer, and subsequent intimal hyperplasia and graft loss. Off-pump - surgery and endoscopic vein harvesting, which are known to reduce surgical - morbidity, have been shown to be no worse than on-pump surgery and open vein - harvesting, respectively, in terms of vein graft patency. Various gene therapies - can prevent intimal hyperplasia in animal models, but human data obtained so far - have been disappointing. Placing an external stent around a vein graft may reduce - tangential wall stress and subsequent intimal hyperplasia. -FAU - Parang, Pirouz -AU - Parang P -AD - Department of Cardiology, Deborah Heart and Lung Center, Browns Mill, New Jersey, - USA. -FAU - Arora, Rohit -AU - Arora R -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -RN - 0 (Anticholesteremic Agents) -SB - IM -MH - Anticholesteremic Agents/therapeutic use -MH - *Coronary Artery Bypass -MH - Coronary Artery Bypass, Off-Pump -MH - Coronary Vessels/*pathology/physiopathology -MH - Genetic Therapy -MH - Graft Occlusion, Vascular/pathology/*physiopathology/*prevention & control -MH - *Graft Survival -MH - Humans -MH - Risk Factors -MH - Stents -MH - Veins/*pathology/physiopathology -PMC - PMC2691920 -EDAT- 2009/02/14 09:00 -MHDA- 2009/03/28 09:00 -PMCR- 2010/02/01 -CRDT- 2009/02/14 09:00 -PHST- 2009/02/14 09:00 [entrez] -PHST- 2009/02/14 09:00 [pubmed] -PHST- 2009/03/28 09:00 [medline] -PHST- 2010/02/01 00:00 [pmc-release] -AID - S0828-282X(09)70486-6 [pii] -AID - cjc25e057 [pii] -AID - 10.1016/s0828-282x(09)70486-6 [doi] -PST - ppublish -SO - Can J Cardiol. 2009 Feb;25(2):e57-62. doi: 10.1016/s0828-282x(09)70486-6. - -PMID- 21763053 -OWN - NLM -STAT- MEDLINE -DCOM- 20111212 -LR - 20220321 -IS - 1579-2242 (Electronic) -IS - 0300-8932 (Linking) -VI - 64 -IP - 9 -DP - 2011 Sep -TI - [Cardiovascular disorders and rheumatic disease]. -PG - 809-17 -LID - 10.1016/j.recesp.2011.05.009 [doi] -AB - Cardiovascular disease is a common and under-recognized problem in patients with - systemic rheumatic conditions. Patients may present with disease associated heart - involvement at the time of diagnosis or later in the course of the illness. The - manifestations vary by disease, and all structures in the heart can be affected - and may result in significant morbidity and mortality. Manifestations of cardiac - disease in these patients range from subclinical to severe and may require - aggressive immunosuppressive therapy. Early recognition is important for prompt - institution of appropriate therapy. Treatment of disease associated cardiac - involvement is based on severity of disease with more severe manifestations often - requiring a combination of corticosteroid and cytotoxic agent. Premature - atherosclerosis has been increasingly recognized in patients with systemic lupus - erythematosus and rheumatoid arthritis and may result in premature coronary death - when compared to the general population. Aggressive control of systemic - inflammation in these diseases may result in a reduction in the risk of ischemic - heart disease. Although aggressive treatment of the primary rheumatic disease has - been associated with an improvement in mortality rates, specific guidelines for - prevention of ischemic heart disease in this group of patients have not been - formulated and recommendations at this time include aggressive control and - monitoring of traditional risk factors. -CI - Copyright © 2011 Sociedad Española de Cardiología. Published by Elsevier Espana. - All rights reserved. -FAU - Villa-Forte, Alexandra -AU - Villa-Forte A -AD - Center for Vasculitis Care and Research, Department of Rheumatic and Immunologic - Diseases, Cleveland Clinic, Cleveland, Ohio, USA. villaa@ccf.org -FAU - Mandell, Brian F -AU - Mandell BF -LA - spa -PT - English Abstract -PT - Journal Article -PT - Review -TT - Trastornos cardiovasculares y enfermedad reumática. -DEP - 20110716 -PL - Spain -TA - Rev Esp Cardiol -JT - Revista espanola de cardiologia -JID - 0404277 -SB - IM -MH - Arthritis, Rheumatoid/complications -MH - Cardiovascular Diseases/epidemiology/*etiology -MH - Humans -MH - Lupus Erythematosus, Systemic/complications -MH - Rheumatic Diseases/*complications -MH - Risk -MH - Scleroderma, Systemic/complications -MH - Spondylitis, Ankylosing/complications -MH - Vasculitis/complications -EDAT- 2011/07/19 06:00 -MHDA- 2011/12/14 06:00 -CRDT- 2011/07/19 06:00 -PHST- 2011/04/05 00:00 [received] -PHST- 2011/05/25 00:00 [accepted] -PHST- 2011/07/19 06:00 [entrez] -PHST- 2011/07/19 06:00 [pubmed] -PHST- 2011/12/14 06:00 [medline] -AID - S0300-8932(11)00516-1 [pii] -AID - 10.1016/j.recesp.2011.05.009 [doi] -PST - ppublish -SO - Rev Esp Cardiol. 2011 Sep;64(9):809-17. doi: 10.1016/j.recesp.2011.05.009. Epub - 2011 Jul 16. - -PMID- 17912165 -OWN - NLM -STAT- MEDLINE -DCOM- 20080321 -LR - 20101118 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 55 -IP - 5 -DP - 2007 Oct -TI - Emergency percutaneous coronary intervention (PCI) for the care of patients with - ST-elevation myocardial infarction (STEMI). -PG - 593-623 -AB - There is general consensus that emergency percutaneous coronary intervention - (PCI) is the preferred treatment for patients with ST-elevation myocardial - infarction (STEMI), so long as it can be delivered in a timely fashion, by an - experienced' operator and cardiac catheterization laboratory (CCL) team. STEMI is - both a functional and structural issue. Although it has been recognized since the - work of pioneering cardiologists and surgeons in Spokane, Washington, that - approximately 88% of patients presenting within 6 hours of onset of STEMI have an - occluded coronary artery, it is the pathophysiology of myocardial necrosis, and - the varied consequences of necrosis that characterize STEMI. Accordingly, - experience' of both primary operator and cardiac catheterization laboratory (CCL) - crew, in performing an emergency PCI for STEMI, are as much a function of - experience with the treatment of complex MI patients, as experience with coronary - intervention. Rapidly achieving normal coronary artery flow, at both the macro - and micro vascular levels, is the recognized key to aborting the otherwise - progressive wavefront' of myocardial necrosis. The time urgency of decisions - (Time is muscle') make emergency PCI for patients with on-going necrosis, more - like emergency room (ER) care, than like most in-hospital or outpatient care. In - general, most patients with acute coronary syndromes (ACS) are currently thought - to have plaque rupture and/or erosion with subsequent thrombosis and - embolization. Consequences of thrombo-embolism, such as slow flow' or no-reflow' - are in addition to, the structural (anatomic) considerations of PCI in stable - patients (such as ostial location; bifurcation involvement; heavy calcification; - tortuosity of lesion or access to it; length of disease; caliber of - infarct-artery; etc.). Good quality studies have provided strong support for the - specific added value of glycoprotein IIb/IIIa inhibitors (especially abciximab), - dual antiplatelet therapy (the addition of the thienopyridine, clopidogrel, to - aspirin use), and bare-metal stents (BMS), for a broad range of STEMI patients. - The added value of drug-eluting stents (DES) to bare-metal stents (BMS), - primarily in terms of reducing restenosis and repeat revascularization, is - supported by several randomized trials, and a number of registries, despite its - being off-label' from a regulatory standpoint. The recognition of late stent - thrombosis (LST) has raised additional issues, in choosing between these two - options for specific STEMI patients. The added value of a number of other - mechanical approaches to coronary thrombus, such as thrombus removal devices, - and/or distal protection, are more controversial, and perhaps, patient specific. - Whether intravascular ultrasound guidance (IVUS) for stent use should be used for - the majority, or even a specific minority, of STEMI patients, is also - controversial; late-stent thrombosis provides a counter-point. The advantages of - developing a network approach to STEMI care, so as to optimize the number of - patients receiving timely reperfusion, have been demonstrated in Prague, Denmark, - and Minneapolis, among many places. The benefits of both bivalirudin - (anti-thrombin drug with efficacy against clot-bound thrombin, which does not - appear to stimulate platelets) and abciximab (glycoprotein IIb/IIIa inhibitor - which is antibody to platelet receptors), as PCI adjuncts generally, and for - STEMI patients, in particular, are supported by multiple trials. The specific - choice of administering the bolus dose of either, or both, drugs via - intra-coronary (IC) injection follows the precedents' of IC thrombolytics, and IC - small-vessel vasodilators for no-reflow', but it has not been tested by - prospective, randomized trials. Although rapid reperfusion is the first - objective, one cannot ignore the other components of the oxygen delivery chain, - and the importance of each of these components to on-going delivery of oxygen to - all vital organs. A balance must be struck between doing those control' things - which serve to stabilize other vital components of the oxygen-delivery chain, - without digressing too long from the job of re-establishing brisk coronary flow. - The clinical and angiographic heterogeneity of STEMI patients and the array of - available therapeutic approaches make it impossible to obtain specific randomized - trial direction for many of the clinical decisions in an individual emergency PCI - for STEMI. There are a range of reasonable/ appropriate therapeutic choices for a - given emergent PCI performed by multiple experienced and competent operators. The - treatment of STEMI, and high-risk non-STEMI, patients, by means of emergent PCI, - is among the most challenging and rewarding arenas in contemporary medicine. -FAU - Morrison, D A -AU - Morrison DA -AD - Yakima Heart Center, Yakima Regional Hospital, Yakima, WA 98902, USA. - dmorrison1249@msn.com -FAU - Berman, M -AU - Berman M -FAU - El-Amin, O -AU - El-Amin O -FAU - McLaughlin, R T -AU - McLaughlin RT -FAU - Bates, E R -AU - Bates ER -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -SB - IM -MH - *Angioplasty, Balloon, Coronary -MH - Electrocardiography -MH - Emergencies -MH - Evidence-Based Medicine -MH - Heart Conduction System/*physiopathology -MH - Humans -MH - Myocardial Infarction/*diagnosis/physiopathology/*therapy -MH - Practice Guidelines as Topic -MH - Treatment Outcome -RF - 222 -EDAT- 2007/10/04 09:00 -MHDA- 2008/03/22 09:00 -CRDT- 2007/10/04 09:00 -PHST- 2007/10/04 09:00 [pubmed] -PHST- 2008/03/22 09:00 [medline] -PHST- 2007/10/04 09:00 [entrez] -PST - ppublish -SO - Minerva Cardioangiol. 2007 Oct;55(5):593-623. - -PMID- 20028188 -OWN - NLM -STAT- MEDLINE -DCOM- 20100405 -LR - 20220311 -IS - 1744-7682 (Electronic) -IS - 1471-2598 (Linking) -VI - 10 -IP - 2 -DP - 2010 Feb -TI - Is there a role for erythropoietin in cardiovascular disease? -PG - 251-64 -LID - 10.1517/14712590903547819 [doi] -AB - IMPORTANCE OF THE FIELD: Despite the advances in the cardiovascular field, - cardiovascular diseases remain an important health problem with a high mortality - rate. Novel therapeutic attempts that target myocardial ischemia and heart - failure offer attractive adjuncts and/or alternatives to commonly employed - regimens. The development of novel laboratory technologies over the last decade - has led to substantial progress in bringing new therapies to the bedside. AREAS - COVERED IN THIS REVIEW: Current experimental and clinical trials in the use of - erythropoietin (EPO) in cardiovascular diseases are reviewed. WHAT THE READER - WILL GAIN: This review will widen knowledge of the therapeutic potential of EPO's - non-erythropoietic beneficial effects in a clinical cardiovascular setting. TAKE - HOME MESSAGE: Results from preclinical trials regarding the non-erythropoietic - effects of erythropoietin are really encouraging. Further clinical studies are - warranted to define the beneficial role of EPO in the clinical setting of - coronary artery disease, heart failure and peripheral artery disease. -FAU - Vogiatzi, Georgia -AU - Vogiatzi G -AD - Athens University Medical School, Hippokration Hospital, First Cardiology Unit, - Vasilissis Sofias 114, 115 28, Athens, Greece. -FAU - Briasoulis, Alexandros -AU - Briasoulis A -FAU - Tousoulis, Dimitris -AU - Tousoulis D -FAU - Papageorgiou, Nikolaos -AU - Papageorgiou N -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Opin Biol Ther -JT - Expert opinion on biological therapy -JID - 101125414 -RN - 0 (Receptors, Erythropoietin) -RN - 0 (Recombinant Proteins) -RN - 11096-26-7 (Erythropoietin) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*drug therapy -MH - Cardiovascular Physiological Phenomena -MH - Clinical Trials as Topic -MH - Erythropoietin/deficiency/*physiology/*therapeutic use -MH - Heart Failure/drug therapy -MH - Humans -MH - Myocardial Infarction/drug therapy -MH - Receptors, Erythropoietin/physiology -MH - Recombinant Proteins -RF - 96 -EDAT- 2009/12/24 06:00 -MHDA- 2010/04/07 06:00 -CRDT- 2009/12/24 06:00 -PHST- 2009/12/24 06:00 [entrez] -PHST- 2009/12/24 06:00 [pubmed] -PHST- 2010/04/07 06:00 [medline] -AID - 10.1517/14712590903547819 [doi] -PST - ppublish -SO - Expert Opin Biol Ther. 2010 Feb;10(2):251-64. doi: 10.1517/14712590903547819. - -PMID- 23856652 -OWN - NLM -STAT- MEDLINE -DCOM- 20140213 -LR - 20220317 -IS - 1347-4820 (Electronic) -IS - 1346-9843 (Linking) -VI - 77 -IP - 8 -DP - 2013 -TI - The substrate and ablation of ventricular tachycardia in patients with - nonischemic cardiomyopathy. -PG - 1957-66 -AB - The term "nonischemic cardiomyopathy" (NICM) designates a myocardial disease - characterized by mechanical and/or electrical dysfunction in the absence of - significant coronary artery disease, valvular heart disease, hypertension, or - congenital heart disease. Although sustained ventricular tachycardia (VT) occurs - in only 5% of patients with NICM, it is an important cause of sudden cardiac - death. In this review we summarize the current understanding of the anatomic and - electrophysiologic substrates of VT in the different types of NICM. In addition, - we discuss recent progress and experience with catheter ablation of VT in these - patients.  -FAU - Liuba, Ioan -AU - Liuba I -AD - Section of Cardiac Electrophysiology, Cardiovascular Division, Hospital of the - University of Pennsylvania, Philadelphia, PA 19004, USA. -FAU - Marchlinski, Francis E -AU - Marchlinski FE -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130712 -PL - Japan -TA - Circ J -JT - Circulation journal : official journal of the Japanese Circulation Society -JID - 101137683 -SB - IM -MH - Cardiomyopathies/complications/pathology/physiopathology/*surgery -MH - Catheter Ablation/*methods -MH - Death, Sudden, Cardiac/pathology/prevention & control -MH - Humans -MH - Tachycardia, Ventricular/complications/pathology/physiopathology/*surgery -EDAT- 2013/07/17 06:00 -MHDA- 2014/02/14 06:00 -CRDT- 2013/07/17 06:00 -PHST- 2013/07/17 06:00 [entrez] -PHST- 2013/07/17 06:00 [pubmed] -PHST- 2014/02/14 06:00 [medline] -AID - DN/JST.JSTAGE/circj/CJ-13-0758 [pii] -AID - 10.1253/circj.cj-13-0758 [doi] -PST - ppublish -SO - Circ J. 2013;77(8):1957-66. doi: 10.1253/circj.cj-13-0758. Epub 2013 Jul 12. - -PMID- 25696612 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20201001 -IS - 1568-5888 (Print) -IS - 1568-5888 (Linking) -VI - 14 -IP - 4 -DP - 2006 Apr -TI - Erectile dysfunction in patients with cardiovascular disease. -PG - 139-146 -AB - Erectile dysfunction is a highly prevalent disease, especially in - cardiovascular-compromised men. Many of the well-established risk factors for - cardiovascular disease are also risk factors for erectile dysfunction. A - correlation between erectile dysfunction and endothelial dysfunction is well - established. It is postulated that erectile dysfunction with an arteriovascular - aetiology can predate and be an indicator of potential coronary artery disease. - In this paper we will attempt to increase awareness among cardiologists for the - predictive value of erectile dysfunction for future cardiovascular disease in - order to optimise cardiovascular risk management. The treatment of erectile - dysfunction and cardiovascular interactions is also discussed in detail. -FAU - Ophuis, A J M Oude -AU - Ophuis AJ -FAU - Nijeholt, A A B Lycklama À -AU - Nijeholt AA -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Neth Heart J -JT - Netherlands heart journal : monthly journal of the Netherlands Society of - Cardiology and the Netherlands Heart Foundation -JID - 101095458 -PMC - PMC2557170 -OTO - NOTNLM -OT - cardiovascular diseases -OT - endothelium -OT - men -OT - prognosis -OT - risk factors -OT - sex -EDAT- 2006/04/01 00:00 -MHDA- 2006/04/01 00:01 -PMCR- 2006/04/01 -CRDT- 2015/02/20 06:00 -PHST- 2015/02/20 06:00 [entrez] -PHST- 2006/04/01 00:00 [pubmed] -PHST- 2006/04/01 00:01 [medline] -PHST- 2006/04/01 00:00 [pmc-release] -PST - ppublish -SO - Neth Heart J. 2006 Apr;14(4):139-146. - -PMID- 20840192 -OWN - NLM -STAT- MEDLINE -DCOM- 20120524 -LR - 20120126 -IS - 1755-5922 (Electronic) -IS - 1755-5914 (Linking) -VI - 30 -IP - 1 -DP - 2012 Feb -TI - Role of antiischemic agents in the management of non-ST elevation acute coronary - syndrome (NSTE-ACS). -PG - e16-22 -LID - 10.1111/j.1755-5922.2010.00225.x [doi] -AB - Non-ST elevation acute coronary syndrome (NSTE-ACS) is the commonest acute - presentation of coronary artery disease (CAD). Mortality and morbidity of the - condition has improved substantially over the last few decades as a result of the - cumulative effect of multiple interventions acting via different mechanisms. - Despite a significant increase in the rate of coronary intervention, medical - therapy continues to retain a central role in the treatment of NSTE-ACS - particularly in frail patients where revascularization is inappropriate or when - it is incomplete. Several antiischemic agents have been used in the treatment of - the condition. Beta blockers are often the first-line choice with calcium channel - blockers and nitrates being used as an alternative when beta blockers are - contraindicated, or as an addition to achieve optimal symptom control. Newer - agents, such as nicorandil, ivabradine, and ranolazine have also been used in - refractory cases. Although most of these agents have been extensively studied in - large randomized controlled trials in patients with stable CAD or ST elevation - acute coronary syndrome (STE-ACS), the evidence supporting their use in NSTE-ACS - is less clear cut. In this article, we review various drugs available for - controlling ischemia and the latest evidence in support of their use in NSTE-ACS. -CI - © 2010 Blackwell Publishing Ltd. -FAU - El-Kadri, Moutaz -AU - El-Kadri M -AD - Liverpool Heart and Chest Hospital NHS Foundation Trust, Thomas Drive, Liverpool, - UK. moutazkad@hotmail.com -FAU - Sharaf-Dabbagh, Hala -AU - Sharaf-Dabbagh H -FAU - Ramsdale, David -AU - Ramsdale D -LA - eng -PT - Journal Article -PT - Review -DEP - 20100915 -PL - England -TA - Cardiovasc Ther -JT - Cardiovascular therapeutics -JID - 101319630 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Cardiovascular Agents) -RN - 0 (Vasodilator Agents) -SB - IM -MH - Acute Coronary Syndrome/*drug therapy/physiopathology -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Calcium Channel Blockers/therapeutic use -MH - Cardiovascular Agents/*therapeutic use -MH - Evidence-Based Medicine -MH - Humans -MH - Myocardial Ischemia/*drug therapy/physiopathology -MH - Treatment Outcome -MH - Vasodilator Agents/therapeutic use -EDAT- 2010/09/16 06:00 -MHDA- 2012/05/25 06:00 -CRDT- 2010/09/16 06:00 -PHST- 2010/09/16 06:00 [entrez] -PHST- 2010/09/16 06:00 [pubmed] -PHST- 2012/05/25 06:00 [medline] -AID - 10.1111/j.1755-5922.2010.00225.x [doi] -PST - ppublish -SO - Cardiovasc Ther. 2012 Feb;30(1):e16-22. doi: 10.1111/j.1755-5922.2010.00225.x. - Epub 2010 Sep 15. - -PMID- 17963678 -OWN - NLM -STAT- MEDLINE -DCOM- 20080110 -LR - 20250529 -IS - 1081-5589 (Print) -IS - 1081-5589 (Linking) -VI - 55 -IP - 6 -DP - 2007 Sep -TI - Calcific aortic valve disease: imaging studies and therapeutic interventions. -PG - 292-8 -LID - 10.2310/6650.2007.00009 [doi] -AB - Echocardiography is the predominant imaging method used for patients with aortic - valve disease because of its excellent diagnostic accuracy, high reproducibility - and noninvasive nature. Cardiac catheterization is typically reserved for - patients in whom the diagnosis remains unclear, those requiring coronary - angiography prior to valve replacement, and in the setting of complex valve - disease. Cardiac computed tomography (CT) has recently been applied as a research - tool to quantify the amount of aortic valve calcium (AVC), which has served as a - clinical end point in several medical therapy trials. Medical therapy for aortic - valve disease remains an active area of clinical research. Multiple retrospective - studies have shown a benefit for 3-hydroxy-3-methylglutaryl coenzyme A reductase - inhibitors (HMG-CoA reductase inhibitors or statins) in reducing disease - progression. However, two recently completed prospective, randomized trials - yielded conflicting results. The data for using angiotensin converting enzyme - (ACE) inhibitors are in the preliminary stages. This review will focus on imaging - methods that are available for patients with aortic valve disease and summarize - the recent trials that have evaluated medical therapy aimed to reduce progression - of aortic valve disease. -FAU - Shavelle, David M -AU - Shavelle DM -AD - Division of Cardiology, Harbor-UCLA Medical Center, Torrance, CA 90509, USA. - dshavelle@hotmail.com -LA - eng -GR - R13 RR023236/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Review -PL - England -TA - J Investig Med -JT - Journal of investigative medicine : the official publication of the American - Federation for Clinical Research -JID - 9501229 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - *Aortic Valve -MH - Calcinosis/*diagnosis/*therapy -MH - Cardiac Catheterization -MH - Catheterization -MH - Echocardiography -MH - Heart Valve Diseases/*diagnosis/*therapy -MH - Heart Valve Prosthesis Implantation -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Tomography, X-Ray Computed -RF - 35 -EDAT- 2007/10/30 09:00 -MHDA- 2008/01/11 09:00 -CRDT- 2007/10/30 09:00 -PHST- 2007/10/30 09:00 [pubmed] -PHST- 2008/01/11 09:00 [medline] -PHST- 2007/10/30 09:00 [entrez] -AID - 10.2310/6650.2007.00009 [doi] -PST - ppublish -SO - J Investig Med. 2007 Sep;55(6):292-8. doi: 10.2310/6650.2007.00009. - -PMID- 21154256 -OWN - NLM -STAT- MEDLINE -DCOM- 20110325 -LR - 20220309 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 17 -IP - 6 -DP - 2010 -TI - Prognostic significance of cardiac magnetic resonance imaging: Update 2010. -PG - 549-57 -AB - Cardiac magnetic resonance imaging (CMR) has become an indispensible imaging - technique for the diagnosis and treatment of patients with cardiovascular - diseases. Technical advances in the past have rendered CMR unique in the - evaluation of cardiovascular anatomy, physiology, and pathophysiology due to its - unique ability to produce high resolution tomographic images of the human heart - and vessels in any arbitrary orientation, with soft tissue contrast that is - superior to competing imaging modalities without the use of ionizing radiation. - CMR imaging is the gold standard for assessing left and right ventricular - function and for detecting myocardial tissue abnormalities like edema, - infarction, or scars. For prognostic reasons abnormal structure and dysfunction - of the heart, and the detection of myocardial ischemia and/ /or myocardial scars - are the main targets for CMR imaging. In this review we briefly describe the - prognostic significance of several CMR imaging techniques and special CMR - parameters in patients with coronary artery disease (CAD), with cardiomyopathies, - and with chronic heart failure. Myocardial ischemia proved to be a strong - predictor of an adverse outcome in patients with CAD. Microvascular obstruction - in acute myocardial infarction is a new and independent parameter of negative - left ventricular remodeling and a worse prognosis. Myocardial scars in patients - with CAD and unrecognized myocardial infarction heralds a negative outcome. Scar - in patients with dilated or hypertrophic cardiomyopathy are a strong predictor of - both life-threatening ventricular tachyarrhythmias and prognosis. CMR imaging may - improve the assessment of inter- and intraventricular dyssynchrony and provide - prognostic information by detecting myocardial scars. -FAU - Hombach, Vinzenz -AU - Hombach V -AD - Department of Internal Medicine II, University Hospital of Ulm, Germany. - vinzenz.hombach@uni-ulm.de -FAU - Merkle, Nico -AU - Merkle N -FAU - Bernhard, Peter -AU - Bernhard P -FAU - Rasche, Volker -AU - Rasche V -FAU - Rottbauer, Wolfgang -AU - Rottbauer W -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -RN - 0 (Contrast Media) -SB - IM -MH - Contrast Media -MH - Coronary Circulation -MH - Heart Diseases/*diagnosis/pathology/physiopathology -MH - Humans -MH - *Magnetic Resonance Imaging/methods -MH - Myocardium/pathology -MH - Predictive Value of Tests -MH - Prognosis -MH - Severity of Illness Index -MH - Ventricular Function, Left -MH - Ventricular Function, Right -EDAT- 2010/12/15 06:00 -MHDA- 2011/03/26 06:00 -CRDT- 2010/12/15 06:00 -PHST- 2010/12/15 06:00 [entrez] -PHST- 2010/12/15 06:00 [pubmed] -PHST- 2011/03/26 06:00 [medline] -PST - ppublish -SO - Cardiol J. 2010;17(6):549-57. - -PMID- 20519242 -OWN - NLM -STAT- MEDLINE -DCOM- 20110110 -LR - 20220410 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 31 -IP - 13 -DP - 2010 Jul -TI - Glycaemic control in acute coronary syndromes: prognostic value and therapeutic - options. -PG - 1557-64 -LID - 10.1093/eurheartj/ehq162 [doi] -AB - Type 2 diabetes and acute coronary syndromes (ACS) are widely interconnected. - Individuals with type 2 diabetes are more likely than non-diabetic subjects to - experience silent or manifest episodes of myocardial ischaemia as the first - presentation of coronary artery disease. Insulin resistance, inflammation, - microvascular disease, and a tendency to thrombosis are common in these patients. - Intensive blood glucose control with intravenous insulin infusion has been - demonstrated to significantly reduce morbidity and mortality in critically ill - hyperglycaemic patients admitted to an intensive care unit (ICU). Direct glucose - toxicity likely plays a crucial role in explaining the clinical benefits of - intensive insulin therapy in such critical patients. However, the difficult - implementation of nurse-driven protocols for insulin infusion able to lead to - rapid and effective blood glucose control without significant episodes of - hypoglycaemia has led to poor implementations of insulin infusion protocols in - coronary care units, and cardiologists now to consider alternative drugs for this - purpose. New intravenous or oral agents include the incretin glucagon-like - peptide 1 (GLP1), its analogues, and dipeptidyl peptidase-4 inhibitors, which - potentiate the activity of GLP1 and thus enhance glucose-dependent insulin - secretion. Improved glycaemic control with protective effects on myocardial and - vascular tissues, with lesser side effects and a better therapeutic compliance, - may represent an important therapeutic potential for this class of drugs in - acutely ill patients in general and patients with ACS in particular. Such drugs - should be known by practicing cardiologists for their possible use in ICUs in the - years to come. -FAU - De Caterina, Raffaele -AU - De Caterina R -AD - Institute of Cardiology and Center of Excellence on Aging, G. d'Annunzio - University-Chieti, C/o Ospedale SS. Annunziata, Via dei Vestini, I-66013 Chieti, - Italy. rdecater@unich.it -FAU - Madonna, Rosalinda -AU - Madonna R -FAU - Sourij, Harald -AU - Sourij H -FAU - Wascher, Thomas -AU - Wascher T -LA - eng -PT - Journal Article -PT - Review -DEP - 20100602 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (Blood Glucose) -RN - 0 (Hypoglycemic Agents) -RN - 0 (Incretins) -RN - 89750-14-1 (Glucagon-Like Peptide 1) -SB - IM -MH - Acute Coronary Syndrome/metabolism/*prevention & control -MH - Blood Glucose/metabolism -MH - Diabetes Mellitus, Type 2/metabolism/*prevention & control -MH - Diabetic Angiopathies/metabolism/*prevention & control -MH - Glucagon-Like Peptide 1/metabolism -MH - Humans -MH - Hypoglycemic Agents/*therapeutic use -MH - Incretins/physiology -MH - Prognosis -EDAT- 2010/06/04 06:00 -MHDA- 2011/01/11 06:00 -CRDT- 2010/06/04 06:00 -PHST- 2010/06/04 06:00 [entrez] -PHST- 2010/06/04 06:00 [pubmed] -PHST- 2011/01/11 06:00 [medline] -AID - ehq162 [pii] -AID - 10.1093/eurheartj/ehq162 [doi] -PST - ppublish -SO - Eur Heart J. 2010 Jul;31(13):1557-64. doi: 10.1093/eurheartj/ehq162. Epub 2010 - Jun 2. - -PMID- 19615486 -OWN - NLM -STAT- MEDLINE -DCOM- 20090805 -LR - 20220318 -IS - 1873-1740 (Electronic) -IS - 0033-0620 (Linking) -VI - 52 -IP - 1 -DP - 2009 Jul-Aug -TI - Elevated heart rate: a "new" cardiovascular risk factor? -PG - 1-5 -LID - 10.1016/j.pcad.2009.06.001 [doi] -AB - A number of epidemiologic studies and several experimental lines of research - point to high heart rate as a main risk factor for cardiovascular disease. - However, translating research into clinical practice has been a challenge - throughout medical history. From the present symposium, it appears clear that - this is particularly the case for heart rate. The complex nature of atherogenesis - makes it difficult to establish the role of a putative risk factor because of the - correlations and complex interactions among factors. The pathogenetic mechanisms - for the connection of resting heart rate with atherosclerosis and cardiovascular - morbidity have been elaborated extensively in the chapter papers of this - symposium, suggesting that there is a causal relationship between heart rate and - cardiovascular mortality. The benefit of heart rate reduction has been proved in - patients with coronary artery disease or congestive heart failure. Until now it - has been difficult to determine whether modulation of heart rate is beneficial - also in patients free of cardiac diseases. This concern, however, does not in any - fashion suggest that health care professionals should pay less attention to this - clinical variable. The impressive amount of available epidemiologic data show - support for the continued effort to raise awareness of the clinical importance of - resting heart rate among health care professionals. -FAU - Palatini, Paolo -AU - Palatini P -AD - Department of Clinical and Experimental Medicine, University of Padova, Padova, - Italy. palatini@unipd.it -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Prog Cardiovasc Dis -JT - Progress in cardiovascular diseases -JID - 0376442 -SB - IM -MH - Cardiovascular Diseases/diagnosis/mortality/*physiopathology -MH - Cardiovascular System/*physiopathology -MH - *Heart Rate -MH - Humans -MH - Risk Factors -MH - Tachycardia/complications/therapy -RF - 46 -EDAT- 2009/07/21 09:00 -MHDA- 2009/08/06 09:00 -CRDT- 2009/07/21 09:00 -PHST- 2009/07/21 09:00 [entrez] -PHST- 2009/07/21 09:00 [pubmed] -PHST- 2009/08/06 09:00 [medline] -AID - S0033-0620(09)00038-3 [pii] -AID - 10.1016/j.pcad.2009.06.001 [doi] -PST - ppublish -SO - Prog Cardiovasc Dis. 2009 Jul-Aug;52(1):1-5. doi: 10.1016/j.pcad.2009.06.001. - -PMID- 22795278 -OWN - NLM -STAT- MEDLINE -DCOM- 20120924 -LR - 20130321 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 164 -IP - 1 -DP - 2012 Jul -TI - Prognostic utility of erectile dysfunction for cardiovascular disease in younger - men and those with diabetes. -PG - 21-8 -LID - 10.1016/j.ahj.2012.04.006 [doi] -AB - Multiple published studies have established erectile dysfunction (ED) as an - independent risk marker for cardiovascular disease (CVD). In fact, incident ED - has a similar or greater predictive value for cardiovascular events than - traditional risk factors including smoking, hyperlipidemia, and family history of - myocardial infarction. Here, we review evidence that supports ED as a - particularly significant harbinger of CVD in 2 populations: men <60 years of age - and those with diabetes. Although addition of ED to the Framingham Risk Score - only modestly improved the 10-year predictive capacity of the Framingham Risk - Score for myocardial infarction or coronary death data in men enrolled in the - Massachusetts Male Aging Study, other epidemiologic studies suggest that the - predictive value of ED is quite strong in younger men. Indeed, in the Olmstead - County Study, men 40 to 49 years of age with ED had a 50-fold higher incidence of - new-incident coronary artery disease than those without ED. However, ED had less - predictive value (5-fold increased risk) for coronary artery disease in men 70 - years and older. Several studies, including a large analysis of more than 6300 - men enrolled in the ADVANCE study, suggest that ED is a particularly powerful - predictor of CVD in diabetic men as well. Based on the literature reviewed here, - we encourage physicians to inquire about ED symptoms in all men more than 30 - years of age with cardiovascular risk factors. Identification of ED, particularly - in men <60 years old and those with diabetes, represents an important first step - toward CVD risk detection and reduction. -CI - Copyright © 2012 Mosby, Inc. All rights reserved. -FAU - Miner, Martin -AU - Miner M -AD - Department of Family Medicine, Warren Alpert School of Medicine, Brown - University, Providence, RI, USA. martin_miner@brown.edu -FAU - Seftel, Allen D -AU - Seftel AD -FAU - Nehra, Ajay -AU - Nehra A -FAU - Ganz, Peter -AU - Ganz P -FAU - Kloner, Robert A -AU - Kloner RA -FAU - Montorsi, Piero -AU - Montorsi P -FAU - Vlachopoulos, Charalambos -AU - Vlachopoulos C -FAU - Ramsey, Melinda -AU - Ramsey M -FAU - Sigman, Mark -AU - Sigman M -FAU - Tilkemeier, Peter -AU - Tilkemeier P -FAU - Jackson, Graham -AU - Jackson G -LA - eng -PT - Journal Article -PT - Review -DEP - 20120607 -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -SB - IM -CIN - J Urol. 2013 Mar;189(3):1035. doi: 10.1016/j.juro.2012.11.161. PMID: 23394661 -MH - Age Factors -MH - Aged -MH - Cardiovascular Diseases/epidemiology/*etiology -MH - Diabetic Cardiomyopathies/*etiology -MH - Endothelium, Vascular/physiopathology -MH - Humans -MH - Impotence, Vasculogenic/*complications -MH - Male -MH - Middle Aged -MH - Prognosis -MH - Risk Factors -MH - Vascular Diseases/complications -EDAT- 2012/07/17 06:00 -MHDA- 2012/09/25 06:00 -CRDT- 2012/07/17 06:00 -PHST- 2012/01/25 00:00 [received] -PHST- 2012/04/12 00:00 [accepted] -PHST- 2012/07/17 06:00 [entrez] -PHST- 2012/07/17 06:00 [pubmed] -PHST- 2012/09/25 06:00 [medline] -AID - S0002-8703(12)00289-X [pii] -AID - 10.1016/j.ahj.2012.04.006 [doi] -PST - ppublish -SO - Am Heart J. 2012 Jul;164(1):21-8. doi: 10.1016/j.ahj.2012.04.006. Epub 2012 Jun - 7. - -PMID- 16755316 -OWN - NLM -STAT- MEDLINE -DCOM- 20060710 -LR - 20220309 -IS - 0828-282X (Print) -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 22 -IP - 7 -DP - 2006 May 15 -TI - The role of global risk assessment in hypertension therapy. -PG - 606-13 -AB - To maximize the benefits of preventive therapy, lipid and hypertension guidelines - increasingly recommend that high-risk individuals be targeted for treatment. An - individual's risk of developing cardiovascular disease depends on many risk - factors, such as age, sex, blood pressure, blood lipid levels, body weight, - physical fitness, smoking habits and familial predisposition. Multivariable - statistical models have therefore been developed to better estimate the global - risk of future coronary events and stroke. A Canadian model is not currently - available because a prospective cohort of sufficient size has not been followed - in Canada. Therefore, global risk assessment among Canadians can only be - completed using models developed in the United States or Europe. In the present - review, cardiovascular risk tools are identified that may be appropriate for - Canadians, including those based on the Framingham model, the Cardiovascular Life - Expectancy Model, the United Kingdom Prospective Diabetes Study (UKPDS) model and - the Systematic COronary Risk Evaluation (SCORE) model. The accuracy of the - Framingham model and the Cardiovascular Life Expectancy Model are also evaluated - using data from a small, prospective Canadian cohort. Finally, a framework is - proposed to assist health care professionals in choosing the global risk tool - most appropriate for their patients. -FAU - Grover, S A -AU - Grover SA -AD - Centre for the Analysis of Cost-Effective Care, Division of Clinical - Epidemiology, The Montreal General Hospital, 1650 Cedar Avenue, Montreal, Quebec, - Canada. steven.grover@mcgill.ca -FAU - Hemmelgarn, Brenda -AU - Hemmelgarn B -FAU - Joseph, Lawrence -AU - Joseph L -FAU - Milot, Alain -AU - Milot A -FAU - Tremblay, Guy -AU - Tremblay G -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Adult -MH - Aged -MH - Canada/epidemiology -MH - Female -MH - Follow-Up Studies -MH - Heart Diseases/epidemiology -MH - Humans -MH - Hypertension/*therapy -MH - Male -MH - Middle Aged -MH - *Models, Cardiovascular -MH - Prospective Studies -MH - ROC Curve -MH - Risk Assessment -MH - Risk Factors -PMC - PMC2560869 -EDAT- 2006/06/07 09:00 -MHDA- 2006/07/13 09:00 -PMCR- 2007/05/01 -CRDT- 2006/06/07 09:00 -PHST- 2006/06/07 09:00 [pubmed] -PHST- 2006/07/13 09:00 [medline] -PHST- 2006/06/07 09:00 [entrez] -PHST- 2007/05/01 00:00 [pmc-release] -AID - S0828-282X(06)70283-5 [pii] -AID - cjc220606 [pii] -AID - 10.1016/s0828-282x(06)70283-5 [doi] -PST - ppublish -SO - Can J Cardiol. 2006 May 15;22(7):606-13. doi: 10.1016/s0828-282x(06)70283-5. - -PMID- 19761396 -OWN - NLM -STAT- MEDLINE -DCOM- 20091203 -LR - 20090918 -IS - 1746-076X (Electronic) -IS - 1746-0751 (Linking) -VI - 4 -IP - 5 -DP - 2009 Sep -TI - Intracoronary blood- or bone marrow-derived cell transplantation in patients with - ischemic heart disease. -PG - 709-19 -LID - 10.2217/rme.09.42 [doi] -AB - Soon after the first experimental scientific investigations of cell - transplantation in various animal models of myocardial infarction and left - ventricular dysfunction, a growing number of clinical trials evaluated the - effects of intracoronary injection of peripheral blood- or bone marrow-derived - cells in patients with myocardial infarction or chronic ischemic heart disease. - In most of these trials, changes in parameters of left ventricular remodeling - over time, such as left ventricular volumes, ejection fraction or infarct size, - were used as trial end points, whereas information on mortality and morbidity - after cell transplantation is sparse. Several meta-analyses, each including - various sets of studies, estimated that intracoronary cell therapy was associated - with small reductions in left ventricular end-systolic volumes and a moderate - increase in left ventricular ejection fraction of 2.9-6.1% over time compared - with control patients. As most of the clinical trials included a limited number - of patients, results vary substantially between different studies. When - evaluating whether effects of intracoronary cell transplantation on parameters of - left ventricular remodeling may be transferable to meaningful consequences in - terms of clinical outcome, the following aspects appear to be imperative. Robust - data on mortality and clinical events based on a sufficient number of patients - are required. Furthermore, effects of cell therapy must be compared with - established therapeutic concepts for the treatment of myocardial infarction, such - as reperfusion therapy or pharmacological interventions aiming at favorably - influencing the remodeling process. Moreover, the potential effects of cell - therapy must be evaluated as treatment options additive to established - therapeutic strategies. -FAU - Reffelmann, Thorsten -AU - Reffelmann T -AD - Klinik und Poliklinik für Innere Medizin B, Universitätsklinikum der - Ernst-Moritz-Arndt-Universität Greifswald, Friedrich-Löffler Str. 23 a, 17475 - Greifswald, Germany. thorstenreffelmann@web.de -FAU - Kloner, Robert A -AU - Kloner RA -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Regen Med -JT - Regenerative medicine -JID - 101278116 -SB - IM -MH - *Bone Marrow Transplantation -MH - Clinical Trials as Topic -MH - Coronary Vessels/cytology -MH - Humans -MH - Meta-Analysis as Topic -MH - Myocardial Ischemia/drug therapy/*surgery -MH - *Peripheral Blood Stem Cell Transplantation -MH - Reperfusion -MH - Stroke Volume -MH - Treatment Outcome -MH - Ventricular Remodeling/drug effects -RF - 58 -EDAT- 2009/09/19 06:00 -MHDA- 2009/12/16 06:00 -CRDT- 2009/09/19 06:00 -PHST- 2009/09/19 06:00 [entrez] -PHST- 2009/09/19 06:00 [pubmed] -PHST- 2009/12/16 06:00 [medline] -AID - 10.2217/rme.09.42 [doi] -PST - ppublish -SO - Regen Med. 2009 Sep;4(5):709-19. doi: 10.2217/rme.09.42. - -PMID- 18334471 -OWN - NLM -STAT- MEDLINE -DCOM- 20081113 -LR - 20161124 -IS - 0195-668X (Print) -IS - 0195-668X (Linking) -VI - 29 -IP - 7 -DP - 2008 Apr -TI - Ultrasound imaging techniques for the evaluation of cardiovascular therapies. -PG - 849-58 -LID - 10.1093/eurheartj/ehn070 [doi] -AB - Cardiovascular disease remains a substantial cause of morbidity and mortality in - the developed world, and is becoming an increasingly important cause of death in - developing countries too. While current cardiovascular treatments can help to - reduce this disease burden, a substantial number of patients still retain a high - risk of experiencing a life-threatening cardiovascular event. Thus, the - development of new therapies capable of reducing this residual risk remains an - important healthcare objective. The time taken to bring new therapies to the - patient in need is lengthened by the unavoidable requirement to demonstrate a - statistically significant benefit in terms of clinical events beyond that - achievable with current treatments. However, clinical trials utilizing surrogate - endpoints-biomarkers of disease progression that manifest before potentially - fatal cardiovascular events occur-have the potential to enhance the process of - drug development by enabling a statistically sound assessment of the efficacy of - new therapies several years in advance of the availability of data from clinical - endpoint trials. Two vascular ultrasound imaging techniques, measurement of - carotid intima-media thickness (CIMT) and intravascular ultrasound (IVUS) of the - coronary arteries, are increasingly being used to assess novel cardiovascular - therapies in surrogate endpoint trials forming integral components of larger - trial programmes utilizing both surrogate and clinical endpoints. The rationale - for the use of CIMT- and IVUS-based surrogates, with supporting evidence from - historical and recent trials, is presented in this review article. -FAU - Kastelein, John J P -AU - Kastelein JJ -AD - Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ - Amsterdam, The Netherlands. j.j.kastelein@amc.uva.nl -FAU - de Groot, Eric -AU - de Groot E -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080311 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -SB - IM -MH - Atherosclerosis/*diagnostic imaging/therapy -MH - Cardiovascular Diseases/*diagnostic imaging/therapy -MH - Carotid Artery Diseases/*diagnostic imaging -MH - Clinical Trials as Topic -MH - Coronary Angiography/methods -MH - Disease Progression -MH - Endpoint Determination -MH - Humans -MH - Risk Factors -MH - Tunica Intima/diagnostic imaging -MH - Tunica Media/diagnostic imaging -MH - Ultrasonography -RF - 59 -EDAT- 2008/03/13 09:00 -MHDA- 2008/11/14 09:00 -CRDT- 2008/03/13 09:00 -PHST- 2008/03/13 09:00 [pubmed] -PHST- 2008/11/14 09:00 [medline] -PHST- 2008/03/13 09:00 [entrez] -AID - ehn070 [pii] -AID - 10.1093/eurheartj/ehn070 [doi] -PST - ppublish -SO - Eur Heart J. 2008 Apr;29(7):849-58. doi: 10.1093/eurheartj/ehn070. Epub 2008 Mar - 11. - -PMID- 17453344 -OWN - NLM -STAT- MEDLINE -DCOM- 20070816 -LR - 20220716 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 12 -IP - 2 -DP - 2007 Jun -TI - Acute heart failure: is there a role for surgery? -PG - 173-8 -AB - Many of the disorders and lesions leading to acute heart failure can be treated - surgically. Modern surgical techniques like the off pump coronary surgery, newer - techniques for the surgical treatment of the mechanical complications of acute MI - and valvular reparative techniques have been added to the surgical armamentarium - in recent years. Modern ventricular assist devices have started their career in - the clinical arena promising to be less invasive. At the same time the spectrum - of indications for mechanical circulatory support continues to witness a rapid - expansion. Technical advances have led to an evolution of surgical strategies. - Heart failure surgery is now in a position to offer improved outcomes, avoidance - of recurrence of acute heart failure or the development of advanced chronic heart - failure. -FAU - Pitsis, A A -AU - Pitsis AA -AD - Thessaloniki Heart Institute, St. Luke's Hospital, Panorama, Thessaloniki, 55236, - Greece. apitsis@otenet.gr -FAU - Anagnostopoulos, C E -AU - Anagnostopoulos CE -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -SB - IM -MH - Acute Disease -MH - Angina, Unstable/complications/*surgery -MH - *Cardiac Surgical Procedures -MH - Cardiomyopathies/complications/*surgery -MH - Heart Failure/etiology/*surgery -MH - Humans -MH - Myocardial Infarction/complications/*surgery -MH - Papillary Muscles/surgery -MH - Treatment Outcome -RF - 26 -EDAT- 2007/04/25 09:00 -MHDA- 2007/08/19 09:00 -CRDT- 2007/04/25 09:00 -PHST- 2007/04/25 09:00 [pubmed] -PHST- 2007/08/19 09:00 [medline] -PHST- 2007/04/25 09:00 [entrez] -AID - 10.1007/s10741-007-9022-5 [doi] -PST - ppublish -SO - Heart Fail Rev. 2007 Jun;12(2):173-8. doi: 10.1007/s10741-007-9022-5. - -PMID- 17318613 -OWN - NLM -STAT- MEDLINE -DCOM- 20080414 -LR - 20181113 -IS - 0946-2716 (Print) -IS - 0946-2716 (Linking) -VI - 85 -IP - 8 -DP - 2007 Aug -TI - Connexin37: a potential modifier gene of inflammatory disease. -PG - 787-95 -AB - There is an increasing appreciation of the importance of gap junction proteins - (connexins) in modulating the severity of inflammatory diseases. Multiple - epidemiological gene association studies have detected a link between a single - nucleotide polymorphism in the human connexin37 (Cx37) gene and coronary artery - disease or myocardial infarction in various populations. This C1019T polymorphism - causes a proline-to-serine substitution (P319S) in the regulatory C terminal tail - of Cx37, a protein that is expressed in the vascular endothelium as well as in - monocytes and macrophages. Indeed, these three cell types are key players in - atherogenesis. In the early phases of atherosclerosis, blood monocytes are - recruited to the sites of injury in response to chemotactic factors. Monocytes - adhere to the dysfunctional endothelium and transmigrate across endothelial cells - to penetrate the arterial intima. In the intima, monocytes proliferate, mature, - and accumulate lipids to progress into macrophage foam cells. This review focuses - on Cx37 and its impact on the cellular and molecular events underlying tissue - function, with particular emphasis of the contribution of the C1019T polymorphism - in atherosclerosis. We will also discuss evidence for a potential mechanism by - which allelic variants of Cx37 are differentially predictive of increased risk - for inflammatory diseases. -FAU - Chanson, Marc -AU - Chanson M -AD - Department of Pediatrics, Geneva University Hospitals, 1211, Geneva 14, - Switzerland. -FAU - Kwak, Brenda R -AU - Kwak BR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20070222 -PL - Germany -TA - J Mol Med (Berl) -JT - Journal of molecular medicine (Berlin, Germany) -JID - 9504370 -RN - 0 (Connexins) -SB - IM -MH - Animals -MH - Connexins/genetics/*physiology -MH - Genetic Predisposition to Disease -MH - Heart Diseases/genetics/pathology/*physiopathology -MH - Humans -MH - Inflammation/genetics/pathology/*physiopathology -MH - Models, Biological -MH - Polymorphism, Single Nucleotide -RF - 108 -EDAT- 2007/02/24 09:00 -MHDA- 2008/04/15 09:00 -CRDT- 2007/02/24 09:00 -PHST- 2006/12/21 00:00 [received] -PHST- 2007/02/01 00:00 [accepted] -PHST- 2007/01/31 00:00 [revised] -PHST- 2007/02/24 09:00 [pubmed] -PHST- 2008/04/15 09:00 [medline] -PHST- 2007/02/24 09:00 [entrez] -AID - 10.1007/s00109-007-0169-2 [doi] -PST - ppublish -SO - J Mol Med (Berl). 2007 Aug;85(8):787-95. doi: 10.1007/s00109-007-0169-2. Epub - 2007 Feb 22. - -PMID- 24121948 -OWN - NLM -STAT- MEDLINE -DCOM- 20140117 -LR - 20131014 -IS - 0034-1193 (Print) -IS - 0034-1193 (Linking) -VI - 104 -IP - 9 -DP - 2013 Sep -TI - [Role of multimodality imaging in patients undergoing transcatheter aortic valve - implantation]. -PG - 498-505 -LID - 10.1701/1331.14739 [doi] -AB - Aortic stenosis is a common disorder. Aortic valve replacement is indicated for - symptomatic patients with severe aortic stenosis, as the prognosis of untreated - patients is poor. However, despite aortic valve replacement can produce dramatic - benefit in the setting of aortic stenosis, morbidity and mortality associated - with surgery has fostered a search for alternatives. Transcatheter aortic valve - replacement is a novel method to treat selected high-risk patients with aortic - stenosis. Patient screening and anatomic measurements of the aortic root, aortic - cusp heights, and the distance between aortic annulus and coronary ostia, as well - as the evaluation of coronary arteries and peripheral arterial disease are of - great importance to ensure procedural success . This review outlines the evolving - role of non-invasive multimodality imaging, including echocardiography, - multidetector computed tomography and cardiac magnetic resonance, in support of - transcatheter aortic valve implantation, and describes how the multimodality - imaging approach is crucial in this clinical setting. -FAU - Bertella, Erika -AU - Bertella E -FAU - Mushtaq, Saima -AU - Mushtaq S -FAU - Andreini, Daniele -AU - Andreini D -FAU - Pontone, Gianluca -AU - Pontone G -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - Ruolo dell'imaging multimodale nei pazienti candidati ad impianto di valvola - aortica percutanea. -PL - Italy -TA - Recenti Prog Med -JT - Recenti progressi in medicina -JID - 0401271 -SB - IM -MH - Algorithms -MH - Aortic Valve Stenosis/*diagnosis/surgery/*therapy -MH - *Cardiac Catheterization -MH - *Echocardiography/methods -MH - *Heart Valve Prosthesis Implantation/methods -MH - Humans -MH - *Magnetic Resonance Imaging, Cine/methods -MH - *Multidetector Computed Tomography/methods -MH - Treatment Outcome -EDAT- 2013/10/15 06:00 -MHDA- 2014/01/18 06:00 -CRDT- 2013/10/15 06:00 -PHST- 2013/10/15 06:00 [entrez] -PHST- 2013/10/15 06:00 [pubmed] -PHST- 2014/01/18 06:00 [medline] -AID - 10.1701/1331.14739 [doi] -PST - ppublish -SO - Recenti Prog Med. 2013 Sep;104(9):498-505. doi: 10.1701/1331.14739. - -PMID- 23047574 -OWN - NLM -STAT- MEDLINE -DCOM- 20130403 -LR - 20161125 -IS - 1644-4345 (Electronic) -IS - 1506-9680 (Linking) -VI - 15 -IP - 1 -DP - 2012 Apr 24 -TI - Myocardial viability assessment in 18FDG PET/CT study (18FDG PET myocardial - viability assessment). -PG - 52-60 -LID - 10.5603/nmr-18731 [doi] -AB - Accurate identification of viable myocardium is crucial in patient qualification - for medical or surgical treatment. Only persons with confirmed cardiac viability - will benefit from revascularization procedures. It is also well known, that the - amount of viable myocardium assessed preoperatively is the best indicator of long - term cardiac event free survival after cardiac intervention.There are several - diagnostic approaches used in current clinical practice for assessment of - myocardial viability. Analysis of wall thickness or myocardial contraction, - evaluation of cardiac perfusion or metabolism can be assessed using following - modalities: Echocardiography, Cardiac Molecular Imaging techniques (PET, SPECT), - Cardiovascular MR or Cardiovascular CT. The article describes the methods and - problems of viability assessment in 18FDG PET study. PET imaging has proved its - accuracy and reproducibility for myocardial ischemia and viability assessment. - However this unique in its ability for showing the particular substrate - metabolism technique has unfortunately some disadvantages: currently achieved PET - resolution is 0.4 cm. However the combined devices multislice computed tomography - scanners with PET (PET/CT) are now widely used in clinical practice. This - combination allows for wider morphologic assessments: coronary calcium scoring - and non-invasive coronary angiography may be added to myocardial - perfusion/metabolic imaging if necessary. -FAU - Kobylecka, Małgorzata -AU - Kobylecka M -AD - Nuclear Medicine Department Warsaw Medical University, Warsaw, Poland. - makob@amwaw.edu.pl -FAU - Mączewska, Joanna -AU - Mączewska J -FAU - Fronczewska-Wieniawska, Katarzyna -AU - Fronczewska-Wieniawska K -FAU - Mazurek, Tomasz -AU - Mazurek T -FAU - Płazińska, Maria Teresa -AU - Płazińska MT -FAU - Królicki, Leszek -AU - Królicki L -LA - eng -PT - Journal Article -PT - Review -DEP - 20120424 -PL - Poland -TA - Nucl Med Rev Cent East Eur -JT - Nuclear medicine review. Central & Eastern Europe -JID - 100886103 -RN - 0Z5B2CJX4D (Fluorodeoxyglucose F18) -SB - IM -MH - Disease -MH - *Fluorodeoxyglucose F18 -MH - Heart/*diagnostic imaging -MH - Humans -MH - Multimodal Imaging/*methods -MH - Myocardium/*cytology/metabolism/pathology -MH - *Positron-Emission Tomography -MH - *Tissue Survival -MH - *Tomography, X-Ray Computed -EDAT- 2012/10/11 06:00 -MHDA- 2013/04/04 06:00 -CRDT- 2012/10/11 06:00 -PHST- 2012/04/26 00:00 [received] -PHST- 2012/04/26 00:00 [accepted] -PHST- 2012/10/11 06:00 [entrez] -PHST- 2012/10/11 06:00 [pubmed] -PHST- 2013/04/04 06:00 [medline] -AID - VM/OJS/J/18731 [pii] -AID - 10.5603/nmr-18731 [doi] -PST - epublish -SO - Nucl Med Rev Cent East Eur. 2012 Apr 24;15(1):52-60. doi: 10.5603/nmr-18731. - -PMID- 17573248 -OWN - NLM -STAT- MEDLINE -DCOM- 20080616 -LR - 20080429 -IS - 1743-9159 (Electronic) -IS - 1743-9159 (Linking) -VI - 6 -IP - 2 -DP - 2008 Apr -TI - Aortic valve surgery: what is the future? -PG - 169-74 -AB - Modern surgical treatment for aortic valve disease has undergone significant - improvements in all areas of this procedure. Successful treatment strategies for - cardiovascular diseases have often been initiated and driven by surgeons. Radical - excision of diseased tissue, repair and replacement strategies lead to long-term - successful treatment of the underlying diseases and clearly improved patient - outcome. In highly developed nations, valve surgery will be increasing applied in - older people, with more co-morbidities and a higher incidence of concomitant - coronary artery disease. Cardiovascular surgeons will be facing increased - competition from the catheter-based procedures; these are already applied - clinically, and their numbers will rise in near future. Right now interventional - cardiologists supported by some cardiac surgeons are on their way to transform - some conventional open surgical procedures into catheter-based less invasive - interventions, such as valve repair and replacement. Cardiovascular surgery is - undergoing a rapid transformation; socio-economic factors and recent advances in - medical technology contribute to these changes. Further developments will come, - and surgeons with all their expertise in the treatment of valvular heart disease - need to be part of it. Cardiovascular surgeons have to adapt the exciting new - approaches of transapical and transfemoral transcatheter valve implantation - techniques. -FAU - Hudorović, Narcis -AU - Hudorović N -AD - University Department of Endo and Vascular Surgery, University Hospital Sestre - milosrdnice, Vinogradska 29, 10000 Zagreb, Croatia. narcis.hudorovic@zg.htnet.hr -LA - eng -PT - Journal Article -PT - Review -DEP - 20070501 -PL - United States -TA - Int J Surg -JT - International journal of surgery (London, England) -JID - 101228232 -SB - IM -MH - Aortic Valve/*surgery -MH - Forecasting -MH - *Heart Valve Prosthesis -MH - Heart Valve Prosthesis Implantation/*methods/trends -MH - Humans -MH - Prosthesis Design -RF - 30 -EDAT- 2007/06/19 09:00 -MHDA- 2008/06/17 09:00 -CRDT- 2007/06/19 09:00 -PHST- 2007/02/13 00:00 [received] -PHST- 2007/04/22 00:00 [revised] -PHST- 2007/04/23 00:00 [accepted] -PHST- 2007/06/19 09:00 [pubmed] -PHST- 2008/06/17 09:00 [medline] -PHST- 2007/06/19 09:00 [entrez] -AID - S1743-9191(07)00077-5 [pii] -AID - 10.1016/j.ijsu.2007.04.009 [doi] -PST - ppublish -SO - Int J Surg. 2008 Apr;6(2):169-74. doi: 10.1016/j.ijsu.2007.04.009. Epub 2007 May - 1. - -PMID- 21324934 -OWN - NLM -STAT- MEDLINE -DCOM- 20120105 -LR - 20110504 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 32 -IP - 9 -DP - 2011 May -TI - Controversies in cardiovascular medicine. Benefits of surgery in obstructive - hypertrophic cardiomyopathy: bring septal myectomy back for European patients. -PG - 1055-8 -LID - 10.1093/eurheartj/ehr006 [doi] -AB - Hypertrophic cardiomyopathy (HCM), a heterogeneous genetic heart disease with - global distribution, is an important cause of heart failure disability at any - age. For 50 years, surgical septal myectomy has been the preferred and primary - treatment strategy for most HCM patients with progressive, drug refractory - functional limitation due to left ventricular (LV) outflow tract obstruction. - With very low surgical mortality at experienced centres, septal myectomy reliably - abolishes impedance to LV outflow and heart failure-related symptoms, restores - quality of life, and importantly is associated with long-term survival similar to - that in the general population. Nevertheless, alternatives to surgical management - are necessary for selected HCM patients. For example, after a brief flirtation - with dual-chamber pacing 20 years ago, percutaneous alcohol septal ablation has - garnered a large measure of enthusiasm and a dedicated following in the - interventional cardiology community, achieving benefits for patients, - paradoxically, by virtue of producing a transmural myocardial infarct. However, - an unintended consequence has been the virtual obliteration of the surgical - option for HCM patients in Europe, where several robust myectomy programmes once - existed. Therefore, clear differences are now evident internationally regarding - management strategies for symptomatic obstructive HCM. The surgical option is now - unavailable to many patients based solely on geography, including some who would - likely benefit more substantially from surgical myectomy than from catheter-based - alcohol ablation. It is our aspiration that this discussion will generate - reconsideration and resurgence of interest in surgical septal myectomy as a - treatment option for severely symptomatic obstructive HCM patients within Europe. -FAU - Maron, Barry J -AU - Maron BJ -AD - Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 - E. 28th Street, Minneapolis, MN 55407, USA. hcm.maron@mhif.org -FAU - Yacoub, Magdi -AU - Yacoub M -FAU - Dearani, Joseph A -AU - Dearani JA -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110214 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -SB - IM -CIN - Eur Heart J. 2011 May;32(9):1059-64. doi: 10.1093/eurheartj/ehr013. PMID: - 21447511 -MH - Cardiomyopathy, Hypertrophic/*surgery -MH - Catheter Ablation/methods -MH - Coronary Care Units/supply & distribution -MH - Europe -MH - Heart Failure/surgery -MH - Heart Septum/*surgery -MH - Humans -MH - Quality of Life -MH - Risk Factors -MH - Surgicenters/supply & distribution -MH - Survival Analysis -MH - Ventricular Outflow Obstruction/*surgery -EDAT- 2011/02/18 06:00 -MHDA- 2012/01/06 06:00 -CRDT- 2011/02/18 06:00 -PHST- 2011/02/18 06:00 [entrez] -PHST- 2011/02/18 06:00 [pubmed] -PHST- 2012/01/06 06:00 [medline] -AID - ehr006 [pii] -AID - 10.1093/eurheartj/ehr006 [doi] -PST - ppublish -SO - Eur Heart J. 2011 May;32(9):1055-8. doi: 10.1093/eurheartj/ehr006. Epub 2011 Feb - 14. - -PMID- 18787732 -OWN - NLM -STAT- MEDLINE -DCOM- 20081113 -LR - 20211020 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Print) -IS - 0828-282X (Linking) -VI - 24 Suppl D -IP - Suppl D -DP - 2008 Sep -TI - Abdominal obesity and the metabolic syndrome: a surgeon's perspective. -PG - 19D-23D -AB - Over the past decade, a major shift in the clinical risk factors in the - population undergoing a cardiac surgery has been observed. In the general - population, an increasing prevalence of obesity has largely contributed to the - development of cardiovascular disorders. Obesity is a heterogeneous condition in - which body fat distribution largely determines metabolic perturbations. - Consequently, individuals characterized by increased abdominal fat deposition and - the so-called metabolic syndrome (MetS) have a higher risk of developing coronary - artery disease. Recent studies have also emphasized that visceral obesity is a - strong risk factor for the development of heart valve diseases. In fact, - individuals characterized by visceral obesity and its metabolic consequences, - such as the small dense low-density lipoprotein phenotype, have a faster - progression rate of aortic stenosis, which is related to increased valvular - inflammation. Furthermore, the degenerative process of implanted bioprostheses is - increased in subjects with the MetS and/or diabetes, suggesting that a process - akin to atherosclerosis could be involved in the failure of bioprostheses. In - addition to being an important risk factor for the development of cardiovascular - disorders, the MetS is increasing the operative mortality risk following coronary - artery bypass graft surgery. Thus, recent evidence supports visceral obesity as a - global risk factor that is affecting the development of many heart disorders, and - that is also impacting negatively on the results of patients undergoing surgical - treatment for cardiovascular diseases. In the present paper, recent concepts - surrounding the MetS and its implications in various cardiovascular disorders are - reviewed along with the clinical implications. -FAU - Mathieu, Patrick -AU - Mathieu P -AD - Laval Hospital, Department of Surgery, Laval University, Sainte-Foy, Quebec. - patrick.mathieu@chg.ulaval.ca -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Cardiac Surgical Procedures/*methods -MH - Heart Diseases/epidemiology/etiology/*surgery -MH - Humans -MH - Metabolic Syndrome/*complications/epidemiology -MH - Morbidity -MH - Obesity/*complications/epidemiology -MH - Prognosis -MH - Risk Factors -PMC - PMC2794452 -EDAT- 2008/10/31 09:00 -MHDA- 2008/11/14 09:00 -PMCR- 2009/09/01 -CRDT- 2008/10/31 09:00 -PHST- 2008/10/31 09:00 [pubmed] -PHST- 2008/11/14 09:00 [medline] -PHST- 2008/10/31 09:00 [entrez] -PHST- 2009/09/01 00:00 [pmc-release] -AID - S0828-282X(08)71045-6 [pii] -AID - cjc24019d [pii] -AID - 10.1016/s0828-282x(08)71045-6 [doi] -PST - ppublish -SO - Can J Cardiol. 2008 Sep;24 Suppl D(Suppl D):19D-23D. doi: - 10.1016/s0828-282x(08)71045-6. - -PMID- 22185655 -OWN - NLM -STAT- MEDLINE -DCOM- 20120921 -LR - 20120125 -IS - 1179-187X (Electronic) -IS - 1175-3277 (Linking) -VI - 12 -IP - 1 -DP - 2012 Feb 1 -TI - Managing arrhythmias before and after aortic valve surgery in children. -PG - 23-34 -LID - 10.2165/11596350-000000000-00000 [doi] -AB - The proximity of the coronary arteries and the bundle of His to the aortic valve - may contribute to the pathogenesis of arrhythmias in patients with aortic valve - disease. Severe aortic valve disease may also adversely alter left ventricular - hemodynamics (end-diastolic dimensions and wall stress) and thus create a - substrate for ventricular arrhythmias before any intervention is performed. The - severity of these arrhythmias depends on the severity of the underlying substrate - (or the specific problem, such as aortic stenosis or aortic regurgitation), the - age at which the aortic valve intervention was performed, the type of - intervention (i.e. transcatheter aortic valve interventions or open aortic valve - replacement or repair), and the reversibility of the altered hemodynamics after - surgery. Both bradyarrhythmias and tachyarrhythmias are known complications of - aortic valve interventions. Although data are scant, this review summarizes the - incidence of arrhythmias before and after aortic valve interventions from a - pediatric perspective. -FAU - Patel, Jyoti Kandlikar -AU - Patel JK -AD - Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. -FAU - Iyer, V Ramesh -AU - Iyer VR -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -SB - IM -MH - Aortic Valve/pathology/*surgery -MH - Arrhythmias, Cardiac/etiology/physiopathology/*therapy -MH - Child -MH - Disease Management -MH - Heart Valve Diseases/physiopathology/*surgery -MH - Heart Valve Prosthesis Implantation/*adverse effects -MH - Humans -MH - Incidence -MH - Postoperative Complications/etiology/physiopathology/*therapy -EDAT- 2011/12/22 06:00 -MHDA- 2012/09/22 06:00 -CRDT- 2011/12/22 06:00 -PHST- 2011/12/22 06:00 [entrez] -PHST- 2011/12/22 06:00 [pubmed] -PHST- 2012/09/22 06:00 [medline] -AID - 10.2165/11596350-000000000-00000 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2012 Feb 1;12(1):23-34. doi: - 10.2165/11596350-000000000-00000. - -PMID- 19390499 -OWN - NLM -STAT- MEDLINE -DCOM- 20090824 -LR - 20090424 -IS - 0026-4806 (Print) -IS - 0026-4806 (Linking) -VI - 100 -IP - 2 -DP - 2009 Apr -TI - Atrial fibrillation and congestive heart failure. -PG - 137-43 -AB - Atrial fibrillation (AF) and congestive heart failure (CHF) are commonly - encountered together, either condition predisposing to the other. The presence of - each condition increases the morbidity and mortality associated with the other - and their coexistence complicates patient management. Common risk factors include - age, hypertension, diabetes mellitus and coronary artery disease. This article - addresses the complex interplay between AF and CHF with regards to shared - mechanisms, effects on prognosis, management issues and available, - pharmacological and non-pharmacological therapeutic options. -FAU - Bourke, T -AU - Bourke T -AD - Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine David - Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA. -FAU - Boyle, N G -AU - Boyle NG -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Med -JT - Minerva medica -JID - 0400732 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Atrial Fibrillation/*complications/mortality/therapy -MH - Catheter Ablation -MH - Electric Countershock -MH - Heart Failure/*complications/mortality/prevention & control -MH - Heart Rate -MH - Humans -MH - Risk Factors -RF - 36 -EDAT- 2009/04/25 09:00 -MHDA- 2009/08/25 09:00 -CRDT- 2009/04/25 09:00 -PHST- 2009/04/25 09:00 [entrez] -PHST- 2009/04/25 09:00 [pubmed] -PHST- 2009/08/25 09:00 [medline] -PST - ppublish -SO - Minerva Med. 2009 Apr;100(2):137-43. - -PMID- 17345160 -OWN - NLM -STAT- MEDLINE -DCOM- 20070614 -LR - 20220716 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 12 -IP - 1 -DP - 2007 Mar -TI - Interpretation of B-type natriuretic peptide in cardiac disease and other - comorbid conditions. -PG - 23-36 -AB - B-Type natriuretic peptide (BNP) is elevated in states of increased ventricular - wall stress. BNP is most commonly used to rule out congestive heart failure (CHF) - in dyspneic patients. BNP levels are influenced by age, gender and, to a - surprisingly large extent, by body mass index (BMI). In addition, it can be - elevated in a wide variety of clinical settings with or without CHF. BNP is - elevated in other cardiac disease states such as the acute coronary syndromes, - diastolic dysfunction, atrial fibrillation (AF), amyloidosis, restrictive - cardiomyopathy (RCM), and valvular heart disease. BNP is elevated in non-cardiac - diseases such as pulmonary hypertension, chronic obstructive pulmonary disease, - pulmonary embolism, and renal failure. BNP is also elevated in the setting of - critical illness such as in acute decompensated CHF (ADHF) and sepsis. This - variation across clinical settings has significant implications given the - increasing frequency with which BNP testing is being performed. It is important - for clinicians to understand how to appropriately interpret BNP in light of the - comorbidities of individual patients to maximize its clinical utility. We will - review the molecular biology and physiology of natriuretic peptides as well as - the relevant literature on the utilization of BNP in CHF as well as in other - important clinical situations, conditions that are commonly associated with CHF - and or dyspnea. -FAU - Burke, Michael A -AU - Burke MA -AD - Department of Internal Medicine, Feinberg School of Medicine, Northwestern - University, Chicago, IL, USA. -FAU - Cotts, William G -AU - Cotts WG -LA - eng -PT - Journal Article -PT - Review -DEP - 20070308 -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Biomarkers) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Animals -MH - Biomarkers -MH - Comorbidity -MH - Critical Illness -MH - Dyspnea/*blood -MH - Heart Diseases/*blood/metabolism -MH - Heart Failure/blood/metabolism -MH - Humans -MH - Lung Diseases/blood -MH - Natriuretic Peptide, Brain/genetics/*metabolism -MH - Predictive Value of Tests -MH - Renal Insufficiency/blood -MH - Sensitivity and Specificity -RF - 139 -EDAT- 2007/03/09 09:00 -MHDA- 2007/06/15 09:00 -CRDT- 2007/03/09 09:00 -PHST- 2007/01/15 00:00 [received] -PHST- 2007/01/17 00:00 [accepted] -PHST- 2007/03/09 09:00 [pubmed] -PHST- 2007/06/15 09:00 [medline] -PHST- 2007/03/09 09:00 [entrez] -AID - 10.1007/s10741-007-9002-9 [doi] -PST - ppublish -SO - Heart Fail Rev. 2007 Mar;12(1):23-36. doi: 10.1007/s10741-007-9002-9. Epub 2007 - Mar 8. - -PMID- 20888519 -OWN - NLM -STAT- MEDLINE -DCOM- 20101123 -LR - 20250529 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Print) -IS - 0735-1097 (Linking) -VI - 56 -IP - 16 -DP - 2010 Oct 12 -TI - Rebuilding the damaged heart: the potential of cytokines and growth factors in - the treatment of ischemic heart disease. -PG - 1287-97 -LID - 10.1016/j.jacc.2010.05.039 [doi] -AB - Cytokine therapy promises to provide a noninvasive treatment option for ischemic - heart disease. Cytokines are thought to influence angiogenesis directly via - effects on endothelial cells or indirectly through progenitor cell-based - mechanisms or by activating the expression of other angiogenic agents. Several - cytokines mobilize progenitor cells from the bone marrow or are involved in the - homing of mobilized cells to ischemic tissue. The recruited cells contribute to - myocardial regeneration both as a structural component of the regenerating tissue - and by secreting angiogenic or antiapoptotic factors, including cytokines. To - date, randomized, controlled clinical trials have not reproduced the efficacy - observed in pre-clinical and small-scale clinical investigations. Nevertheless, - the list of promising cytokines continues to grow, and combinations of cytokines, - with or without concurrent progenitor cell therapy, warrant further - investigation. -CI - Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Beohar, Nirat -AU - Beohar N -AD - Northwestern University, Chicago, IL, USA. -FAU - Rapp, Jonathan -AU - Rapp J -FAU - Pandya, Sanjay -AU - Pandya S -FAU - Losordo, Douglas W -AU - Losordo DW -LA - eng -GR - R01 HL077428/HL/NHLBI NIH HHS/United States -GR - R01 HL080137/HL/NHLBI NIH HHS/United States -GR - R01 HL057516/HL/NHLBI NIH HHS/United States -GR - HL-57516/HL/NHLBI NIH HHS/United States -GR - HL-53354/HL/NHLBI NIH HHS/United States -GR - HL-77428/HL/NHLBI NIH HHS/United States -GR - R01 HL095874/HL/NHLBI NIH HHS/United States -GR - R37 HL053354/HL/NHLBI NIH HHS/United States -GR - R01 HL053354/HL/NHLBI NIH HHS/United States -GR - R01 HL063414/HL/NHLBI NIH HHS/United States -GR - HL-80137/HL/NHLBI NIH HHS/United States -GR - HL-63414/HL/NHLBI NIH HHS/United States -GR - HL-95874/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Cytokines) -RN - 0 (Intercellular Signaling Peptides and Proteins) -SB - IM -MH - Coronary Vessels/*drug effects -MH - Cytokines/*pharmacology/*therapeutic use -MH - Humans -MH - Intercellular Signaling Peptides and Proteins/pharmacology/therapeutic use -MH - Myocardial Ischemia/*drug therapy -MH - Neovascularization, Physiologic -MH - Treatment Outcome -PMC - PMC3123891 -MID - NIHMS304822 -EDAT- 2010/10/05 06:00 -MHDA- 2010/12/14 06:00 -PMCR- 2011/06/27 -CRDT- 2010/10/05 06:00 -PHST- 2008/07/08 00:00 [received] -PHST- 2010/04/21 00:00 [revised] -PHST- 2010/05/10 00:00 [accepted] -PHST- 2010/10/05 06:00 [entrez] -PHST- 2010/10/05 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -PHST- 2011/06/27 00:00 [pmc-release] -AID - S0735-1097(10)02794-4 [pii] -AID - 10.1016/j.jacc.2010.05.039 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2010 Oct 12;56(16):1287-97. doi: 10.1016/j.jacc.2010.05.039. - -PMID- 20149453 -OWN - NLM -STAT- MEDLINE -DCOM- 20100513 -LR - 20250529 -IS - 1532-3102 (Electronic) -IS - 0143-4004 (Print) -IS - 0143-4004 (Linking) -VI - 31 Suppl -IP - Suppl -DP - 2010 Mar -TI - Review: The placenta is a programming agent for cardiovascular disease. -PG - S54-9 -LID - 10.1016/j.placenta.2010.01.002 [doi] -AB - Cardiovascular disease remains the number one killer in western nations in spite - of declines in death rates following improvements in clinical care. It has been - 20 years since David Barker and colleagues showed that slow rates of prenatal - growth predict mortality from ischemic heart disease. Thus, fetal undergrowth and - its associated cardiovascular diseases must be due, in part, to placental - inadequacies. This conclusion is supported by a number of studies linking - placental characteristics with various adult diseases. A "U" shaped relationship - between placental-to-fetal weight ratio and heart disease provides powerful - evidence that placental growth-regulating processes initiate vulnerabilities for - later heart disease in offspring. Recent evidence from Finland indicates that - placental morphological characteristics predict risks for coronary artery - disease, heart failure, hypertension and several cancers. The level of risk - imparted by placental shape is sex dependent. Further, maternal diet and body - composition strongly influence placental growth, levels of inflammation, nutrient - transport capacity and oxidative stress, with subsequent effects on offspring - health. Several animal models have demonstrated the placental roots of - vulnerability for heart disease. These include findings that abnormal endothelial - development in the placenta is associated with undergrown myocardial walls in the - embryo, and that placental insufficiency leads to depressed maturation and - proliferation of working cardiomyocytes in the fetal heart. Together these models - suggest that the ultimate fitness of the heart is determined by hemodynamic, - growth factor, and oxygen/nutrient cues before birth, all of which are - influenced, if not regulated by the placenta. -CI - Copyright 2010 Elsevier Ltd. All rights reserved. -FAU - Thornburg, K L -AU - Thornburg KL -AD - Heart Research Center, Oregon Health & Science University, 3303 SW Bond Avenue, - CH15H, Portland, OR 97239, USA. thornbur@ohsu.edu -FAU - O'Tierney, P F -AU - O'Tierney PF -FAU - Louey, S -AU - Louey S -LA - eng -GR - P01 HD034430/HD/NICHD NIH HHS/United States -GR - P01HD34430/HD/NICHD NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100209 -PL - Netherlands -TA - Placenta -JT - Placenta -JID - 8006349 -SB - IM -MH - Adult -MH - Cardiovascular Diseases/*etiology/physiopathology -MH - Female -MH - Heart/*embryology/physiopathology -MH - Humans -MH - Maternal-Fetal Exchange/physiology -MH - Placenta/*physiopathology -MH - Pregnancy -MH - Prenatal Exposure Delayed Effects/*physiopathology -MH - Prenatal Nutritional Physiological Phenomena/physiology -PMC - PMC2846089 -MID - NIHMS177889 -EDAT- 2010/02/13 06:00 -MHDA- 2010/05/14 06:00 -PMCR- 2011/03/01 -CRDT- 2010/02/13 06:00 -PHST- 2009/11/17 00:00 [received] -PHST- 2009/12/31 00:00 [revised] -PHST- 2010/01/04 00:00 [accepted] -PHST- 2010/02/13 06:00 [entrez] -PHST- 2010/02/13 06:00 [pubmed] -PHST- 2010/05/14 06:00 [medline] -PHST- 2011/03/01 00:00 [pmc-release] -AID - S0143-4004(10)00008-1 [pii] -AID - 10.1016/j.placenta.2010.01.002 [doi] -PST - ppublish -SO - Placenta. 2010 Mar;31 Suppl(Suppl):S54-9. doi: 10.1016/j.placenta.2010.01.002. - Epub 2010 Feb 9. - -PMID- 16980722 -OWN - NLM -STAT- MEDLINE -DCOM- 20071113 -LR - 20220330 -IS - 1462-0332 (Electronic) -IS - 1462-0324 (Linking) -VI - 45 Suppl 4 -DP - 2006 Oct -TI - Cardiac arrhythmias and conduction disturbances in autoimmune rheumatic diseases. -PG - iv39-42 -AB - Rhythm and conduction disturbances and sudden cardiac death (SCD) are important - manifestations of cardiac involvement in autoimmune rheumatic diseases (ARDs). In - patients with rheumatoid arthritis (RA), a major cause of SCD is atherosclerotic - coronary artery disease, leading to acute coronary syndrome and ventricular - arrhythmias. In systemic lupus erythematosus (SLE), sinus tachycardia, atrial - fibrillation and atrial ectopic beats are the major cardiac arrhythmias. In some - cases, sinus tachycardia may be the only manifestation of cardiac involvement. - The most frequent cardiac rhythm disturbances in systemic sclerosis (SSc) are - premature ventricular contractions (PVCs), often appearing as monomorphic, single - PVCs, or rarely as bigeminy, trigeminy or pairs. Transient atrial fibrillation, - flutter or paroxysmal supraventricular tachycardia are also described in 20-30% - of SSc patients. Non-sustained ventricular tachycardia was described in 7-13%, - while SCD is reported in 5-21% of unselected patients with SSc. The conduction - disorders are more frequent in ARD than the cardiac arrhythmias. In RA, - infiltration of the atrioventricular (AV) node can cause right bundle branch - block in 35% of patients. AV block is rare in RA, and is usually complete. In SLE - small vessel vasculitis, the infiltration of the sinus or AV nodes, or active - myocarditis can lead to first-degree AV block in 34-70% of patients. In contrast - to RA, conduction abnormalities may regress when the underlying disease is - controlled. In neonatal lupus, 3% of infants whose mothers are antibody positive - develop complete heart block. Conduction disturbances in SSc are due to fibrosis - of sinoatrial node, presenting as abnormal ECG, bundle and fascicular blocks and - occur in 25-75% of patients. -FAU - Seferović, P M -AU - Seferović PM -AD - Department of Cardiology, Institute for Cardiovascular Diseases of the Clinical - Center of Serbia, Koste Todorovica 8, 11000 Belgrade, Serbia. eseferov@eunet.yu -FAU - Ristić, A D -AU - Ristić AD -FAU - Maksimović, R -AU - Maksimović R -FAU - Simeunović, D S -AU - Simeunović DS -FAU - Ristić, G G -AU - Ristić GG -FAU - Radovanović, G -AU - Radovanović G -FAU - Seferović, D -AU - Seferović D -FAU - Maisch, B -AU - Maisch B -FAU - Matucci-Cerinic, M -AU - Matucci-Cerinic M -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Rheumatology (Oxford) -JT - Rheumatology (Oxford, England) -JID - 100883501 -SB - IM -MH - Arrhythmias, Cardiac/*complications/physiopathology/therapy -MH - Autoimmune Diseases/*complications/physiopathology -MH - *Electrocardiography -MH - Heart Conduction System/*physiopathology -MH - Humans -MH - Rheumatic Diseases/*complications/physiopathology -RF - 30 -EDAT- 2006/09/19 09:00 -MHDA- 2007/11/14 09:00 -CRDT- 2006/09/19 09:00 -PHST- 2006/09/19 09:00 [pubmed] -PHST- 2007/11/14 09:00 [medline] -PHST- 2006/09/19 09:00 [entrez] -AID - 45/suppl_4/iv39 [pii] -AID - 10.1093/rheumatology/kel315 [doi] -PST - ppublish -SO - Rheumatology (Oxford). 2006 Oct;45 Suppl 4:iv39-42. doi: - 10.1093/rheumatology/kel315. - -PMID- 16922166 -OWN - NLM -STAT- MEDLINE -DCOM- 20060912 -LR - 20091111 -IS - 0003-3928 (Print) -IS - 0003-3928 (Linking) -VI - 55 -IP - 4 -DP - 2006 Aug -TI - [Exercise training in cardiac patients: usefulness of the cardiopulmonary - exercise test]. -PG - 178-86 -AB - Exercise training is currently including in the treatment of coronary arterial - disease patients, in patients with left ventricular dysfunction as well as in - patients who underwent cardiac transplantation or cardiac surgery. However - methods of prescribing exercise-training programs are difficult to determine and - must be adapted for each patient Exercise test with gas analysis through the - determination of anaerobic threshold may help to understand the - physiopathological mechanism related to exercise limitation in these patients. - Exercise test may help to precise exercise intensity during cardiac - rehabilitation and may assess the benefits on exercise tolerance. -FAU - Tabet, J Y -AU - Tabet JY -AD - Service de cardiologie, centre de réadaptation cardiovasculaire de la Brie, 27, - rue Sainte-Christine, 77174 Villeneuve-Saint-Denis, France. jtabet@free.fr -FAU - Meurin, P -AU - Meurin P -FAU - Ben Driss, A -AU - Ben Driss A -FAU - Weber, H -AU - Weber H -FAU - Renaud, N -AU - Renaud N -FAU - Cohen-Solal, A -AU - Cohen-Solal A -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Réadaptation des patients porteurs d'une cardiopathie: intérêt de la mesure des - echanges gazeux a l'effort (VO2). -PL - France -TA - Ann Cardiol Angeiol (Paris) -JT - Annales de cardiologie et d'angeiologie -JID - 0142167 -SB - IM -MH - Exercise Test/*methods -MH - *Exercise Therapy -MH - Exercise Tolerance -MH - Heart Diseases/*rehabilitation -MH - Humans -MH - Oxygen Consumption -MH - Respiratory Function Tests -RF - 53 -EDAT- 2006/08/23 09:00 -MHDA- 2006/09/13 09:00 -CRDT- 2006/08/23 09:00 -PHST- 2006/08/23 09:00 [pubmed] -PHST- 2006/09/13 09:00 [medline] -PHST- 2006/08/23 09:00 [entrez] -AID - S0003-3928(06)00024-2 [pii] -AID - 10.1016/j.ancard.2006.04.004 [doi] -PST - ppublish -SO - Ann Cardiol Angeiol (Paris). 2006 Aug;55(4):178-86. doi: - 10.1016/j.ancard.2006.04.004. - -PMID- 23661199 -OWN - NLM -STAT- MEDLINE -DCOM- 20140314 -LR - 20211021 -IS - 1546-9549 (Electronic) -IS - 1546-9530 (Linking) -VI - 10 -IP - 3 -DP - 2013 Sep -TI - How are depression and type D personality associated with outcomes in chronic - heart failure patients? -PG - 244-53 -LID - 10.1007/s11897-013-0139-7 [doi] -AB - This review aims to summarize the current evidence for the association of - depression and Type D personality with clinical and patient-centred outcomes and - self-care in chronic heart failure (CHF) patients. Emotional distress is highly - prevalent in CHF patients. In contrast to results in coronary artery disease, - there is inconsistent evidence for the adverse effects of depression and Type D - on prognosis. Type D and depression are important predictors of impaired health - status in CHF, and patients characterised by depression or Type D report reduced - self-care. Pathophysiological processes associated with depression and Type D are - discussed, as they may contribute to disease progression. Future research may - benefit from taking inconsistencies in and problems with assessment of depression - and Type D into account, as well as focusing on the network of - psychophysiological and behavioural factors to elucidate their precise role in - CHF patients with depression or Type D. Furthermore, it is advised that - clinicians address the observed differences in self-care behaviours to improve - health in CHF patients with depression or Type D personality. -FAU - Widdershoven, Jos -AU - Widdershoven J -AD - CoRPS - Center of Research on Psychology in Somatic Diseases, Department of - Medical and Clinical Psychology, Tilburg University, P.O. Box 90153, 5000LE, - Tilburg, The Netherlands. jwiddershoven@tsz.nl -FAU - Kessing, Dionne -AU - Kessing D -FAU - Schiffer, Angélique -AU - Schiffer A -FAU - Denollet, Johan -AU - Denollet J -FAU - Kupper, Nina -AU - Kupper N -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Heart Fail Rep -JT - Current heart failure reports -JID - 101196487 -SB - IM -MH - Chronic Disease -MH - Depression/*psychology -MH - Heart Failure/mortality/physiopathology/*psychology/rehabilitation -MH - Humans -MH - Patient Readmission -MH - Patient-Centered Care/methods -MH - Prognosis -MH - Self Care/psychology -MH - *Type D Personality -EDAT- 2013/05/11 06:00 -MHDA- 2014/03/15 06:00 -CRDT- 2013/05/11 06:00 -PHST- 2013/05/11 06:00 [entrez] -PHST- 2013/05/11 06:00 [pubmed] -PHST- 2014/03/15 06:00 [medline] -AID - 10.1007/s11897-013-0139-7 [doi] -PST - ppublish -SO - Curr Heart Fail Rep. 2013 Sep;10(3):244-53. doi: 10.1007/s11897-013-0139-7. - -PMID- 20629345 -OWN - NLM -STAT- MEDLINE -DCOM- 20100813 -LR - 20221207 -IS - 0008-7335 (Print) -IS - 0008-7335 (Linking) -VI - 149 -IP - 5 -DP - 2010 -TI - [Therapy of hyperglycemia and risk of ischemic heart disease: 2010]. -PG - 235-6, 238-41 -AB - Prevalence of coronary artery diseases in diabetic patiens is high. The risk of - the cardiovascular complications increases in concordance with higher - glycosylated hemoglobin. Treatment of the hyperglycemia, dyslipidemia and - hypertension is preventive of the cardiovascular complications. -FAU - Charvát, Jirí -AU - Charvát J -AD - Univerzita Karlova v Praze, 2. lékarská fakulta, Interní klinika FN Motol. -FAU - Kvapil, Milan -AU - Kvapil M -LA - cze -PT - Journal Article -PT - Review -TT - Vztah terapie hyperglykémie a riziko ischemické choroby srdecní: rok 2010. -PL - Czech Republic -TA - Cas Lek Cesk -JT - Casopis lekaru ceskych -JID - 0004743 -RN - 0 (Blood Glucose) -RN - 0 (Glycated Hemoglobin A) -RN - 0 (Hypoglycemic Agents) -SB - IM -MH - Blood Glucose/analysis -MH - *Diabetes Complications -MH - Diabetes Mellitus/*blood/drug therapy -MH - Glycated Hemoglobin/analysis -MH - Humans -MH - Hypoglycemic Agents/*therapeutic use -MH - Myocardial Ischemia/complications/*prevention & control -MH - Risk Factors -RF - 23 -EDAT- 2010/07/16 06:00 -MHDA- 2010/08/14 06:00 -CRDT- 2010/07/16 06:00 -PHST- 2010/07/16 06:00 [entrez] -PHST- 2010/07/16 06:00 [pubmed] -PHST- 2010/08/14 06:00 [medline] -PST - ppublish -SO - Cas Lek Cesk. 2010;149(5):235-6, 238-41. - -PMID- 16970729 -OWN - NLM -STAT- MEDLINE -DCOM- 20070109 -LR - 20060914 -IS - 0894-0959 (Print) -IS - 0894-0959 (Linking) -VI - 19 -IP - 5 -DP - 2006 Sep-Oct -TI - The cardiovascular effects of arteriovenous fistulas in chronic kidney disease: a - cause for concern? -PG - 349-52 -AB - Arteriovenous fistulas (AVFs) are the preferred type of vascular access, but - relatively little is known regarding their effects on cardiovascular remodeling - and cardiac function. The following is a review regarding the immediate and - long-term complications associated with AVF creation, including the development - of left ventricular hypertrophy, high-output cardiac failure, exacerbation of - coronary ischemia, and the possible contribution to the development of central - vein stenosis. -FAU - MacRae, Jennifer M -AU - MacRae JM -FAU - Levin, Adeera -AU - Levin A -FAU - Belenkie, Israel -AU - Belenkie I -LA - eng -PT - Editorial -PT - Review -PL - United States -TA - Semin Dial -JT - Seminars in dialysis -JID - 8911629 -SB - IM -MH - Arteriovenous Shunt, Surgical/*adverse effects -MH - Constriction, Pathologic/physiopathology -MH - Heart Diseases/*physiopathology -MH - Humans -MH - Kidney Failure, Chronic/*therapy -MH - Renal Dialysis -MH - Subclavian Vein/physiopathology -RF - 35 -EDAT- 2006/09/15 09:00 -MHDA- 2007/01/11 09:00 -CRDT- 2006/09/15 09:00 -PHST- 2006/09/15 09:00 [pubmed] -PHST- 2007/01/11 09:00 [medline] -PHST- 2006/09/15 09:00 [entrez] -AID - SDI185 [pii] -AID - 10.1111/j.1525-139X.2006.00185.x [doi] -PST - ppublish -SO - Semin Dial. 2006 Sep-Oct;19(5):349-52. doi: 10.1111/j.1525-139X.2006.00185.x. - -PMID- 21399925 -OWN - NLM -STAT- MEDLINE -DCOM- 20111115 -LR - 20211020 -IS - 1534-3170 (Electronic) -IS - 1523-3782 (Linking) -VI - 13 -IP - 3 -DP - 2011 Jun -TI - The role of cardiac MR in new-onset heart failure. -PG - 185-93 -LID - 10.1007/s11886-011-0179-0 [doi] -AB - In patients with heart failure, cardiovascular magnetic resonance imaging (CMR) - allows a multifaceted approach to cardiac evaluation by enabling an assessment of - morphology, function, perfusion, viability, tissue characterization, and blood - flow during a single comprehensive examination. Given its accuracy and - reproducibility, many believe CMR is the reference standard for the noninvasive - assessment of ventricular volumes, mass, and function, and offers an ideal means - for the serial assessment of disease progression or treatment response in - individual patients. Delayed-enhancement (DE)-CMR provides a direct assessment of - myopathic processes. This permits a fundamentally different approach than that - traditionally taken to ascertaining the etiology of cardiomyopathy, which is - vital in patients with nonischemic cardiomyopathy and incidental coronary artery - disease and patients with mixed, ischemic and nonischemic cardiomyopathy. Precise - tissue characterization with DE-CMR also improves the diagnosis of left - ventricular thrombus, for which it is the emerging clinical reference standard. - There is a growing body of literature on the utility of CMR for patient risk - stratification, and its potential role in important management decisions such as - for cardiac resynchronization therapy and defibrillator placement. -FAU - Kim, Yong-Jin -AU - Kim YJ -AD - Cardiac MR Research Center, Seoul National University College of Medicine, Seoul, - South Korea. -FAU - Kim, Raymond J -AU - Kim RJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -SB - IM -MH - Cardiac Resynchronization Therapy -MH - Cardiomyopathies/*diagnosis/*etiology/physiopathology -MH - Heart Failure/*complications/*diagnosis/therapy -MH - Humans -MH - *Magnetic Resonance Imaging -MH - Myocardial Ischemia/diagnosis -MH - Prognosis -MH - Thrombosis/complications -EDAT- 2011/03/15 06:00 -MHDA- 2011/11/16 06:00 -CRDT- 2011/03/15 06:00 -PHST- 2011/03/15 06:00 [entrez] -PHST- 2011/03/15 06:00 [pubmed] -PHST- 2011/11/16 06:00 [medline] -AID - 10.1007/s11886-011-0179-0 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2011 Jun;13(3):185-93. doi: 10.1007/s11886-011-0179-0. - -PMID- 23298558 -OWN - NLM -STAT- MEDLINE -DCOM- 20140422 -LR - 20220309 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 167 -IP - 5 -DP - 2013 Sep 1 -TI - Copeptin and cardiovascular disease: a review of a novel neurohormone. -PG - 1750-9 -LID - S0167-5273(12)01668-3 [pii] -LID - 10.1016/j.ijcard.2012.12.039 [doi] -AB - Neurohormones (NHs) in the cascade of the arginine vasopressin (AVP) system have - drawn particular attention in the recent years. Copeptin, the C-terminal portion - of provasopressin, is a novel NH of the AVP system, and is known to be - co-released with AVP from hypothalamus (neurohypophysis). As a surrogate marker - of the AVP system, copeptin has gradually replaced AVP in several clinical - studies largely due to its structural and methodological advantages. Copeptin has - been regarded as a marker of non-specific stress response, and has also been - suggested to have clinical implications in a variety of non-cardiovascular - (pneumonia, sepsis, etc.) and cardiovascular conditions (heart failure and acute - coronary syndromes (ACSs, etc.)). However, current data on relation of copeptin - with other cardiovascular conditions ( arrhythmias, etc.) are still insufficient. - The present review primarily focuses on general features of copeptin, its general - clinical implications, and specifically aims to cover its potential clinical - value in a variety of cardiovascular conditions. -CI - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved. -FAU - Yalta, Kenan -AU - Yalta K -AD - Trakya University, Cardiology Department, Edirne, Turkey. kyalta@gmail.com -FAU - Yalta, Tulin -AU - Yalta T -FAU - Sivri, Nasir -AU - Sivri N -FAU - Yetkin, Ertan -AU - Yetkin E -LA - eng -PT - Journal Article -PT - Review -DEP - 20130105 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Biomarkers) -RN - 0 (Glycopeptides) -RN - 0 (Neurotransmitter Agents) -RN - 0 (copeptins) -SB - IM -MH - Animals -MH - Biomarkers/blood -MH - Cardiovascular Diseases/*blood/*diagnosis -MH - Glycopeptides/*blood -MH - Humans -MH - Neurotransmitter Agents/*blood -OTO - NOTNLM -OT - Arginine vasopressin -OT - Cardiovascular disease -OT - Clinical implication -OT - Copeptin -EDAT- 2013/01/10 06:00 -MHDA- 2014/04/23 06:00 -CRDT- 2013/01/10 06:00 -PHST- 2012/07/14 00:00 [received] -PHST- 2012/10/23 00:00 [revised] -PHST- 2012/12/05 00:00 [accepted] -PHST- 2013/01/10 06:00 [entrez] -PHST- 2013/01/10 06:00 [pubmed] -PHST- 2014/04/23 06:00 [medline] -AID - S0167-5273(12)01668-3 [pii] -AID - 10.1016/j.ijcard.2012.12.039 [doi] -PST - ppublish -SO - Int J Cardiol. 2013 Sep 1;167(5):1750-9. doi: 10.1016/j.ijcard.2012.12.039. Epub - 2013 Jan 5. - -PMID- 17513215 -OWN - NLM -STAT- MEDLINE -DCOM- 20070823 -LR - 20070521 -IS - 1302-8723 (Print) -IS - 1302-8723 (Linking) -VI - 7 -IP - 2 -DP - 2007 Jun -TI - [Anxiety disorder as a potential for sudden death]. -PG - 179-83 -AB - A close association between anxiety disorder and sudden death is known. If any - underlying heart disease exists, it is easy to discuss this association. If it - does not, it is difficult to explain anxiety disorder as a cause of sudden death. - In case of acute anxiety, many complicated physiologic events, which have - capacity of contributing to sudden death, occur. On the other hand, accelerated - atherosclerosis ensues in the case of chronic anxiety, and the latter increases - vulnerability to sudden death through development of coronary events. -FAU - Vural, Mutlu -AU - Vural M -AD - Kirşehir Devlet Hastanesi Kardiyoloji Bölümü, Kirşehir, Türkiye. - heppikalp@yahoo.com -FAU - Başar, Emrullah -AU - Başar E -LA - tur -PT - English Abstract -PT - Journal Article -PT - Review -TT - Anksiyete bozukluğunun ani ölüm yapma potansiyeli. -PL - Turkey -TA - Anadolu Kardiyol Derg -JT - Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology -JID - 101095069 -SB - IM -MH - Anxiety Disorders/*complications/psychology -MH - Death, Sudden, Cardiac/*etiology -MH - Humans -RF - 43 -EDAT- 2007/05/22 09:00 -MHDA- 2007/08/24 09:00 -CRDT- 2007/05/22 09:00 -PHST- 2007/05/22 09:00 [pubmed] -PHST- 2007/08/24 09:00 [medline] -PHST- 2007/05/22 09:00 [entrez] -PST - ppublish -SO - Anadolu Kardiyol Derg. 2007 Jun;7(2):179-83. - -PMID- 18956157 -OWN - NLM -STAT- MEDLINE -DCOM- 20081230 -LR - 20181113 -IS - 0938-7412 (Print) -IS - 0938-7412 (Linking) -VI - 19 -IP - 3 -DP - 2008 Sep -TI - [Exercise testing in cardiology]. -PG - 98-106 -LID - 10.1007/s00399-008-0009-2 [doi] -AB - Cardiac imaging plays an increasing role in exercise testing. However, exercise - testing with ECG remains a classical and basic approach to analyze cardiac - function and to screen for coronary artery disease. Maximal testing, i. e., - terminated by exhaustion of the patient, is important to achieve a reliable - diagnostic result. New parameters have been introduced such as recovery heart - rate, blood pressure and functional capacity. These parameters improve risk - stratification, thus, increasing prognostic power of exercise testing. General - and specific quality management has still to be improved in exercise testing. -FAU - Löllgen, H -AU - Löllgen H -AD - Ehem, Leiter der Klinik für Kardiologile, Pneumologie, Intensivmedizin, - Remscheid, AKL Ruhr-Universität Bochum, Bermesgasse 32 b, 42897 Remscheid, - Deutschland. loellgen@dgsp.de -FAU - Gerke, R -AU - Gerke R -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Belastungs-EKG (Ergometrie). -DEP - 20081025 -PL - Germany -TA - Herzschrittmacherther Elektrophysiol -JT - Herzschrittmachertherapie & Elektrophysiologie -JID - 9425873 -SB - IM -MH - Cardiovascular Diseases/*diagnosis -MH - Electrocardiography/*methods -MH - Exercise Test/*methods -MH - Humans -RF - 30 -EDAT- 2008/10/29 09:00 -MHDA- 2008/12/31 09:00 -CRDT- 2008/10/29 09:00 -PHST- 2008/06/12 00:00 [received] -PHST- 2008/06/26 00:00 [accepted] -PHST- 2008/10/29 09:00 [pubmed] -PHST- 2008/12/31 09:00 [medline] -PHST- 2008/10/29 09:00 [entrez] -AID - 10.1007/s00399-008-0009-2 [doi] -PST - ppublish -SO - Herzschrittmacherther Elektrophysiol. 2008 Sep;19(3):98-106. doi: - 10.1007/s00399-008-0009-2. Epub 2008 Oct 25. - -PMID- 19886787 -OWN - NLM -STAT- MEDLINE -DCOM- 20100218 -LR - 20091105 -IS - 1744-8298 (Electronic) -IS - 1479-6678 (Linking) -VI - 5 -IP - 6 -DP - 2009 Nov -TI - Mesenchymal stromal cells for cardiovascular repair: current status and future - challenges. -PG - 605-17 -LID - 10.2217/fca.09.42 [doi] -AB - Ischemic heart disease is the most common cause of death in most industrialized - countries. Early treatment with stabilizing drugs and mechanical - revascularization by percutaneous coronary intervention or coronary bypass - surgery has reduced the mortality significantly. In spite of improved offers of - treatments in patients with heart failure, the 1-year mortality is still - approximately 20% after the diagnosis has been established. Treatment with stem - cells with the potential to regenerate the damaged myocardium is a relatively new - approach. Mesenchymal stromal cells are a promising source of stem cells for - regenerative therapy. Clinical studies on stem cell therapy for cardiac - regeneration have shown significant improvements in ventricular pump function, - ventricular remodeling, myocardial perfusion, exercise potential and clinical - symptoms compared with conventionally treated control groups. The results of most - studies are promising, but there are still many unanswered questions. In this - review, we explore present preclinical and clinical knowledge regarding the use - of stem cells in cardiovascular regenerative medicine, with special focus on - mesenchymal stromal cells. We take a closer look at sources of stem cells, - delivery method and methods for tracking injected cells. -FAU - Mathiasen, Anders Bruun -AU - Mathiasen AB -AD - Cardiac Stem Cell laboratory & Cardiac Catheterization Laboratory 2014, The Heart - Centre, Rigshospitalet, Copenhagen University Hospital & Faculty of Health - Sciences, Blegdamsvej 9, DK-2100 Copenhagen, Denmark. abbe@mail.dk -FAU - Haack-Sørensen, Mandana -AU - Haack-Sørensen M -FAU - Kastrup, Jens -AU - Kastrup J -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Future Cardiol -JT - Future cardiology -JID - 101239345 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/diagnosis/*therapy -MH - Humans -MH - Magnetic Resonance Imaging -MH - *Mesenchymal Stem Cell Transplantation -MH - Myocardium/*pathology -MH - Regenerative Medicine -RF - 109 -EDAT- 2009/11/06 06:00 -MHDA- 2010/02/19 06:00 -CRDT- 2009/11/06 06:00 -PHST- 2009/11/06 06:00 [entrez] -PHST- 2009/11/06 06:00 [pubmed] -PHST- 2010/02/19 06:00 [medline] -AID - 10.2217/fca.09.42 [doi] -PST - ppublish -SO - Future Cardiol. 2009 Nov;5(6):605-17. doi: 10.2217/fca.09.42. - -PMID- 22340493 -OWN - NLM -STAT- MEDLINE -DCOM- 20120501 -LR - 20250529 -IS - 1878-1551 (Electronic) -IS - 1534-5807 (Print) -IS - 1534-5807 (Linking) -VI - 22 -IP - 2 -DP - 2012 Feb 14 -TI - Coordinating tissue interactions: Notch signaling in cardiac development and - disease. -PG - 244-54 -LID - 10.1016/j.devcel.2012.01.014 [doi] -AB - The Notch pathway is a crucial cell-fate regulator in the developing heart. - Attention in the past centered on Notch function in cardiomyocytes. However, - recent advances demonstrate that region-specific endocardial Notch activity - orchestrates the patterning and morphogenesis of cardiac chambers and valves - through regulatory interaction with multiple myocardial and neural crest signals. - Notch also regulates cardiomyocyte proliferation and differentiation during - ventricular chamber development and is required for coronary vessel - specification. Here, we review these data and highlight disease connections, - including evidence that Notch-Hey-Bmp2 interplay impacts adult heart valve - disease and that Notch contributes to cardiac arrhythmia and pre-excitation - syndromes. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - de la Pompa, José Luis -AU - de la Pompa JL -AD - Program of Cardiovascular Developmental Biology, Department of Cardiovascular - Development and Repair, Centro Nacional de Investigaciones Cardiovasculares - (CNIC), Melchor Fernández Almagro 3, E-28029 Madrid, Spain. jlpompa@cnic.es -FAU - Epstein, Jonathan A -AU - Epstein JA -LA - eng -GR - R01 HL095634/HL/NHLBI NIH HHS/United States -GR - U01 HL100405/HL/NHLBI NIH HHS/United States -GR - U01 HL 100405/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Dev Cell -JT - Developmental cell -JID - 101120028 -RN - 0 (Receptors, Notch) -SB - IM -MH - Adult -MH - *Gene Expression Regulation, Developmental -MH - Heart Diseases/*metabolism/*pathology -MH - Heart Valves/*embryology/*pathology -MH - Humans -MH - Receptors, Notch/genetics/*metabolism -MH - Signal Transduction -PMC - PMC3285259 -MID - NIHMS353774 -EDAT- 2012/02/22 06:00 -MHDA- 2012/05/02 06:00 -PMCR- 2013/02/14 -CRDT- 2012/02/21 06:00 -PHST- 2012/01/20 00:00 [accepted] -PHST- 2012/02/21 06:00 [entrez] -PHST- 2012/02/22 06:00 [pubmed] -PHST- 2012/05/02 06:00 [medline] -PHST- 2013/02/14 00:00 [pmc-release] -AID - S1534-5807(12)00048-2 [pii] -AID - 10.1016/j.devcel.2012.01.014 [doi] -PST - ppublish -SO - Dev Cell. 2012 Feb 14;22(2):244-54. doi: 10.1016/j.devcel.2012.01.014. - -PMID- 23216298 -OWN - NLM -STAT- MEDLINE -DCOM- 20131219 -LR - 20170721 -IS - 1526-4610 (Electronic) -IS - 0017-8748 (Linking) -VI - 53 -IP - 1 -DP - 2013 Jan -TI - QT prolongation, Torsade de Pointes, myocardial ischemia from coronary vasospasm, - and headache medications. Part 2: review of headache medications, drug-drug - interactions, QTc prolongation, and other arrhythmias. -PG - 217-224 -LID - 10.1111/j.1526-4610.2012.02299.x [doi] -AB - Serotonin (5-hydroxytryptamine)(1B/1D) agonists can vasoconstrict coronary and - cerebral arteries. Chest, jaw, and arm discomfort, so-called "triptan - sensations," are often felt to be noncardiac. In Part 1 of this review, the - relationship of triptans, coronary artery narrowing, and spasm was discussed, - along with a case of a 53-year-old woman without cardiac risk factors who - developed polymorphic ventricular tachycardia and cardiac ischemia with acquired - corrected QT (QTc) interval prolongation following oral sumatriptan. In Part 2 of - this review, headache medications, drug-drug interactions, QTc prolongation, and - cardiac arrhythmias are appraised and discussed. Triptans, cardiac arrhythmias, - and ischemia by prescribing information are summarized. The reader is provided - tables on QTc prolongation by medication. The problem of QTc prolongation with a - variety of headache medications at conventional doses, including triptans, - serotonin reuptake inhibitors (selective serotonin reuptake inhibitors and - serotonin norepinephrine reuptake inhibitors), other antidepressants, - antihistamines, and antinauseants should lead to proactively obtaining - electrocardiograms and more vigilant surveillance of headache patients. This may - be the place to start in protecting patients from these cardiac adverse events. -CI - © 2012 American Headache Society. -FAU - Stillman, Mark J -AU - Stillman MJ -AD - Headache Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA. -FAU - Tepper, Deborah E -AU - Tepper DE -AD - Headache Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA. -FAU - Tepper, Stewart J -AU - Tepper SJ -AD - Headache Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA. -FAU - Cho, Leslie -AU - Cho L -AD - Department of Cardiology, Cleveland Clinic, Cleveland, OH, USA. -LA - eng -PT - Case Reports -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121206 -PL - United States -TA - Headache -JT - Headache -JID - 2985091R -RN - 0 (Serotonin Receptor Agonists) -SB - IM -MH - Arrhythmias, Cardiac/chemically induced -MH - Coronary Vasospasm/chemically induced -MH - *Drug Interactions -MH - Electrocardiography/drug effects -MH - Female -MH - Headache/*drug therapy -MH - Humans -MH - Middle Aged -MH - Myocardial Ischemia/chemically induced -MH - Serotonin Receptor Agonists/*adverse effects -MH - Torsades de Pointes/chemically induced -EDAT- 2012/12/12 06:00 -MHDA- 2013/12/20 06:00 -CRDT- 2012/12/11 06:00 -PHST- 2012/10/01 00:00 [accepted] -PHST- 2012/12/11 06:00 [entrez] -PHST- 2012/12/12 06:00 [pubmed] -PHST- 2013/12/20 06:00 [medline] -AID - 10.1111/j.1526-4610.2012.02299.x [doi] -PST - ppublish -SO - Headache. 2013 Jan;53(1):217-224. doi: 10.1111/j.1526-4610.2012.02299.x. Epub - 2012 Dec 6. - -PMID- 21827726 -OWN - NLM -STAT- MEDLINE -DCOM- 20111007 -LR - 20181201 -IS - 1603-9629 (Electronic) -IS - 0907-8916 (Linking) -VI - 58 -IP - 8 -DP - 2011 Aug -TI - On the use of abciximab in percutaneous coronary intervention. -PG - B4312 -FAU - Iversen, Allan Zeeberg -AU - Iversen AZ -AD - Department of Cardiology, Gentofte Universityhospital, Niels Andersensvej 65, - 2900 Hellerup, Denmark. aiversen@dadlnet.dk -LA - eng -PT - Journal Article -PT - Review -PL - Denmark -TA - Dan Med Bull -JT - Danish medical bulletin -JID - 0066040 -RN - 0 (Antibodies, Monoclonal) -RN - 0 (Immunoglobulin Fab Fragments) -RN - 0 (Platelet Aggregation Inhibitors) -RN - X85G7936GV (Abciximab) -SB - IM -MH - Abciximab -MH - Angioplasty, Balloon, Coronary/*methods -MH - Antibodies, Monoclonal/*therapeutic use -MH - Coronary Thrombosis/prevention & control -MH - Humans -MH - Immunoglobulin Fab Fragments/*therapeutic use -MH - Myocardial Infarction/*drug therapy -MH - Platelet Aggregation Inhibitors/*therapeutic use -EDAT- 2011/08/11 06:00 -MHDA- 2011/10/08 06:00 -CRDT- 2011/08/11 06:00 -PHST- 2011/08/11 06:00 [entrez] -PHST- 2011/08/11 06:00 [pubmed] -PHST- 2011/10/08 06:00 [medline] -AID - B4312 [pii] -PST - ppublish -SO - Dan Med Bull. 2011 Aug;58(8):B4312. - -PMID- 16493246 -OWN - NLM -STAT- MEDLINE -DCOM- 20060613 -LR - 20151119 -IS - 1061-5377 (Print) -IS - 1061-5377 (Linking) -VI - 14 -IP - 2 -DP - 2006 Mar-Apr -TI - The paclitaxel-eluting stent in percutaneous coronary intervention: part I: - background and clinical comparison to bare metal stents. -PG - 88-98 -AB - The development of coronary artery stents that release (elute) a drug locally - into the diseased vasculature has revolutionized the practice of interventional - cardiology. These devices were designed to minimize the incidence of in-stent - restenosis that may occur with bare metal stents. The paclitaxel-eluting stent is - the most recent drug-eluting stent approved for use in the United States and is a - bare metal stent coated with paclitaxel that is gradually released from the stent - into the vessel wall with undetectable systemic concentrations of the drug. - Paclitaxel functions to stabilize the assembly of microtubules, thereby - interfering with cell division, motility, and shape, and ultimately inhibiting - smooth muscle cell proliferation and migration, key processes in the development - of neointimal hyperplasia during in-stent restenosis. Clinical trials have - repeatedly demonstrated the superiority of the paclitaxel-eluting stent over the - bare metal stent in terms of reducing restenosis rates and percent stenosis - diameter as well as other angiographic end points. Although the rates of major - adverse cardiac events are reduced with the paclitaxel-eluting stent compared - with the bare metal stent, this is primarily the result of a reduction in the - need for target vessel revascularization, whereas rates of myocardial infarction - and death have not been shown to be significantly affected. -FAU - Gruchalla, Kathryn J A -AU - Gruchalla KJ -AD - University of New Mexico, College of Pharmacy, Albuquerque, New Mexico - 87131-0001, USA. -FAU - Nawarskas, James J -AU - Nawarskas JJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - P88XT4IS4D (Paclitaxel) -SB - IM -MH - Angioplasty, Balloon, Coronary/*instrumentation -MH - Coronary Restenosis/prevention & control -MH - Double-Blind Method -MH - Humans -MH - Multicenter Studies as Topic -MH - Paclitaxel/*administration & dosage -MH - Prospective Studies -MH - Randomized Controlled Trials as Topic -MH - *Stents -RF - 57 -EDAT- 2006/02/24 09:00 -MHDA- 2006/06/14 09:00 -CRDT- 2006/02/24 09:00 -PHST- 2006/02/24 09:00 [pubmed] -PHST- 2006/06/14 09:00 [medline] -PHST- 2006/02/24 09:00 [entrez] -AID - 00045415-200603000-00006 [pii] -AID - 10.1097/01.crd.0000200895.60631.0b [doi] -PST - ppublish -SO - Cardiol Rev. 2006 Mar-Apr;14(2):88-98. doi: 10.1097/01.crd.0000200895.60631.0b. - -PMID- 22999239 -OWN - NLM -STAT- MEDLINE -DCOM- 20130225 -LR - 20120924 -IS - 1551-7136 (Print) -IS - 1551-7136 (Linking) -VI - 8 -IP - 4 -DP - 2012 Oct -TI - Diabetes mellitus and myocardial mitochondrial dysfunction: bench to bedside. -PG - 551-61 -LID - S1551-7136(12)00053-0 [pii] -LID - 10.1016/j.hfc.2012.06.001 [doi] -AB - In diabetics, the risk for development of heart failure is increased even after - adjusting for coronary artery disease and hypertension. Although the cause of - this increased heart failure risk is multifactorial, increasing evidence suggests - that dysfunction of myocardial mitochondria represents an important pathogenetic - factor. To date, no specific therapy exists to treat mitochondrial function in - any cardiac disease. This article presents underlying mechanisms of mitochondrial - dysfunction in the diabetic heart and discusses potential therapeutic options - that may attenuate these mitochondrial derangements. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - König, Alexandra -AU - König A -AD - Department of Cardiology and Angiology, University Hospital of Freiburg, - Hugstetter Strasse 55, Freiburg, Germany. -FAU - Bode, Christoph -AU - Bode C -FAU - Bugger, Heiko -AU - Bugger H -LA - eng -PT - Journal Article -PT - Review -DEP - 20120809 -PL - United States -TA - Heart Fail Clin -JT - Heart failure clinics -JID - 101231934 -RN - 0 (Antioxidants) -SB - IM -MH - Antioxidants/therapeutic use -MH - Diabetes Mellitus, Type 2/*complications/drug therapy/pathology -MH - Heart Failure/drug therapy/*etiology -MH - Humans -MH - Mitochondria/metabolism/pathology -MH - Mitochondrial Diseases/*complications/drug therapy/pathology -MH - Myocardium/metabolism/*pathology -MH - Oxidative Stress -MH - Risk Assessment/methods -EDAT- 2012/09/25 06:00 -MHDA- 2013/02/26 06:00 -CRDT- 2012/09/25 06:00 -PHST- 2012/09/25 06:00 [entrez] -PHST- 2012/09/25 06:00 [pubmed] -PHST- 2013/02/26 06:00 [medline] -AID - S1551-7136(12)00053-0 [pii] -AID - 10.1016/j.hfc.2012.06.001 [doi] -PST - ppublish -SO - Heart Fail Clin. 2012 Oct;8(4):551-61. doi: 10.1016/j.hfc.2012.06.001. Epub 2012 - Aug 9. - -PMID- 24077604 -OWN - NLM -STAT- MEDLINE -DCOM- 20140522 -LR - 20131010 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 28 -IP - 6 -DP - 2013 Nov -TI - Arterial grafting and complete revascularization: challenge or compromise? -PG - 646-53 -LID - 10.1097/HCO.0000000000000001 [doi] -AB - PURPOSE OF REVIEW: Arterial grafting is superior to venous grafting in coronary - artery bypass graft surgery with respect to graft patency and long-term patient - outcome, but it may be difficult to achieve complete arterial revascularization. - RECENT FINDINGS: Use of arterial grafts, especially bilateral internal mammary - artery grafts, is not common, whereas there are clear indications that it may - increase survival. Definitions of complete revascularization are varied and - confusing, making study comparisons difficult. Technical challenges in complete - revascularization with arterial grafts can be minimized by surgical techniques. - Competitive flow in moderately stenosed coronary arteries grafted with arterial - conduits may result in reduced patency. While internal mammary arteries may be - used in arteries with at least 60% stenosis, radial artery and gastroepiploic - grafts are best placed onto coronaries with severe stenosis. Moderate lesions in - the left coronary circulation should be bypassed, but right coronary artery - lesions can be left untouched as there is minimal progression over time. Complete - revascularization may not be necessary or possible in every patient because of - technical challenges. CONCLUSION: Complete revascularization with arterial grafts - presents both technical and physiological challenges. However, with techniques to - maximize length of arterial conduits, knowledge of competitive flow and which - moderate lesions should be addressed, complete revascularization with arterial - grafts can be accomplished in the majority of patients, notwithstanding it may - not be possible or even indicated for every patient. -FAU - Kieser, Teresa M -AU - Kieser TM -AD - aDepartment of Cardiac Sciences, LIBIN Cardiovascular Institute of Alberta, - University of Calgary, Calgary, Alberta, Canada bDepartment of Cardiothoracic - Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands. -FAU - Head, Stuart J -AU - Head SJ -FAU - Kappetein, A Pieter -AU - Kappetein AP -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -SB - IM -MH - Arteries/*transplantation -MH - Coronary Artery Bypass/*methods -MH - Coronary Stenosis/*surgery -MH - Gastroepiploic Artery/transplantation -MH - Graft Occlusion, Vascular/*prevention & control -MH - Humans -MH - Mammary Arteries/transplantation -MH - Myocardial Revascularization/*methods -MH - Radial Artery/transplantation -MH - Treatment Outcome -MH - Vascular Patency -EDAT- 2013/10/01 06:00 -MHDA- 2014/05/23 06:00 -CRDT- 2013/10/01 06:00 -PHST- 2013/10/01 06:00 [entrez] -PHST- 2013/10/01 06:00 [pubmed] -PHST- 2014/05/23 06:00 [medline] -AID - 10.1097/HCO.0000000000000001 [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2013 Nov;28(6):646-53. doi: 10.1097/HCO.0000000000000001. - -PMID- 20454877 -OWN - NLM -STAT- MEDLINE -DCOM- 20101130 -LR - 20240130 -IS - 1532-6551 (Electronic) -IS - 1071-3581 (Linking) -VI - 17 -IP - 4 -DP - 2010 Aug -TI - Radionuclide imaging of cardiac autonomic innervation. -PG - 655-66 -LID - 10.1007/s12350-010-9239-x [doi] -AB - Cardiac autonomic function plays a crucial role in health and disease, with - abnormalities both reflecting the severity of the disease and contributing - specifically to clinical deterioration and poor prognosis. Radiotracer analogs of - the sympathetic mediator norepinephrine have been investigated extensively, and - are at the brink of potential widespread clinical use. The most widely studied - SPECT tracer, I-123 metaiodobenzylguanidine ((123)I-mIBG) has consistently shown - a strong, independent ability to risk stratify patients with advanced congestive - heart failure. Increased global cardiac uptake appears to have a high negative - predictive value in terms of cardiac events, especially death and arrhythmias, - and therefore and may have a role in guiding therapy, particularly by helping to - better select patients unresponsive to conventional medical therapies who would - benefit from device therapies such as an ICD (implantable cardioverter - defibrillator), CRT (cardiac resynchronization therapy), LVAD (left ventricular - assist device), or cardiac transplantation. Cardiac autonomic imaging with SPECT - and PET tracers also shows potential to assess patients following cardiac - transplant, those with primary arrhythmic condition, coronary artery disease, - diabetes mellitus, and during cardiotoxic chemotherapy. Radiotracer imaging of - cardiac autonomic function allows visualization and quantitative measurements of - underlying molecular aspects of cardiac disease, and should therefore provide a - perspective that other cardiac tests cannot. -FAU - Ji, Sang Yong -AU - Ji SY -AD - Department of Nuclear Medicine, Montefiore Medical Center, Albert Einstein - College of Medicine, 111 East-210th Street, Bronx, NY 10467-2490, USA. -FAU - Travin, Mark I -AU - Travin MI -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Nucl Cardiol -JT - Journal of nuclear cardiology : official publication of the American Society of - Nuclear Cardiology -JID - 9423534 -RN - 0 (Radiopharmaceuticals) -SB - IM -MH - Autonomic Nervous System/*diagnostic imaging -MH - Autonomic Nervous System Diseases/complications/*diagnostic imaging -MH - Heart/*diagnostic imaging/*innervation -MH - Heart Diseases/complications/*diagnostic imaging -MH - Humans -MH - *Radiopharmaceuticals -MH - Tomography, Emission-Computed/*methods -EDAT- 2010/05/11 06:00 -MHDA- 2010/12/14 06:00 -CRDT- 2010/05/11 06:00 -PHST- 2010/05/11 06:00 [entrez] -PHST- 2010/05/11 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -AID - S1071-3581(23)04119-3 [pii] -AID - 10.1007/s12350-010-9239-x [doi] -PST - ppublish -SO - J Nucl Cardiol. 2010 Aug;17(4):655-66. doi: 10.1007/s12350-010-9239-x. - -PMID- 19734503 -OWN - NLM -STAT- MEDLINE -DCOM- 20091216 -LR - 20090907 -IS - 1473-0480 (Electronic) -IS - 0306-3674 (Linking) -VI - 43 -IP - 9 -DP - 2009 Sep -TI - Prevention of sudden cardiac death: return to sport considerations in athletes - with identified cardiovascular abnormalities. -PG - 685-9 -LID - 10.1136/bjsm.2008.054882 [doi] -AB - Sudden cardiac death in the athlete is uncommon but extremely visible. In - athletes under age 30, genetic heart disease, including hypertrophic - cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, and ion channel - disorders account for the majority of the deaths. Commotio cordis, involving - blunt trauma to the chest leading to ventricular fibrillation, is also a leading - cause of sudden cardiac death in young athletes. As the athlete ages, coronary - atherosclerosis contributes to an increasing incidence of sudden death during - sporting activities. For athletes with aborted sudden death or arrhythmia-related - syncope, an implantable cardioverter defibrillator is generally indicated, and - they should be restricted from most competitive sports. Participation in - competitive athletics for athletes with heart disease should generally follow the - recently published 36th Bethesda Conference Eligibility Recommendations for - Competitive Athletes with Cardiovascular Abnormalities. -FAU - Link, M S -AU - Link MS -AD - Tufts Medical Center, NEMC Box #197, 750 Washington Street, Boston, MA 02111, - USA. MLink@tuftsmedicalcenter.org -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Br J Sports Med -JT - British journal of sports medicine -JID - 0432520 -SB - IM -MH - Adult -MH - Age Factors -MH - Competitive Behavior -MH - Death, Sudden, Cardiac/etiology/*prevention & control -MH - Female -MH - Heart Diseases/*complications -MH - Humans -MH - Male -MH - Risk Factors -MH - *Sports -MH - Young Adult -RF - 47 -EDAT- 2009/09/08 06:00 -MHDA- 2009/12/17 06:00 -CRDT- 2009/09/08 06:00 -PHST- 2009/09/08 06:00 [entrez] -PHST- 2009/09/08 06:00 [pubmed] -PHST- 2009/12/17 06:00 [medline] -AID - 43/9/685 [pii] -AID - 10.1136/bjsm.2008.054882 [doi] -PST - ppublish -SO - Br J Sports Med. 2009 Sep;43(9):685-9. doi: 10.1136/bjsm.2008.054882. - -PMID- 20715399 -OWN - NLM -STAT- MEDLINE -DCOM- 20100914 -LR - 20171116 -IS - 0021-5252 (Print) -IS - 0021-5252 (Linking) -VI - 61 -IP - 8 Suppl -DP - 2008 Jul -TI - [Cardiovascular surgery for patients with chronic respiratory failure and - respiratory dysfunction]. -PG - 624-9 -AB - Chronic obstructive pulmonary disease is one of the major comorbidities in - elderly patients with heart disease and thoracic aneurysm because of an overlap - of risk factors. Although postoperative ventilator dependency is a major concern, - recent study has suggested chronic obstructive pulmonary disease (COPD) was not a - risk factor for postoperative prolonged mechanical ventilator support for - off-pump coronary artery bypass grafting. Cardiopulmonary bypass may induce acute - lung injury, but short-term cardiopulmonary bypass alone does not give adverse - effect in clinical practice. Perioperative airway management including quitting - smoking, use of bronchodilator, avoiding excessive tracheal suction, and early - extubation may contribute satisfactory outcome. However, a stage IV COPD patient - is contraindicated for cardiac surgery. Patients with interstitial lung disease - can undergo cardiac surgery safely if they have moderate performance status even - when patients are under home oxygen therapy. -FAU - Daitoku, Kazuyuki -AU - Daitoku K -AD - Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate - School of Medicine, Hirosaki, Japan. -FAU - Suzuki, Y -AU - Suzuki Y -FAU - Fukuda, I -AU - Fukuda I -LA - jpn -PT - Journal Article -PT - Review -PL - Japan -TA - Kyobu Geka -JT - Kyobu geka. The Japanese journal of thoracic surgery -JID - 0413533 -SB - IM -MH - Aged -MH - *Cardiovascular Surgical Procedures -MH - Contraindications -MH - Female -MH - Humans -MH - Male -MH - Pulmonary Disease, Chronic Obstructive/*complications -MH - Respiratory Insufficiency/*complications -RF - 20 -EDAT- 2008/07/01 00:00 -MHDA- 2010/09/16 06:00 -CRDT- 2010/08/19 06:00 -PHST- 2010/08/19 06:00 [entrez] -PHST- 2008/07/01 00:00 [pubmed] -PHST- 2010/09/16 06:00 [medline] -PST - ppublish -SO - Kyobu Geka. 2008 Jul;61(8 Suppl):624-9. - -PMID- 19135616 -OWN - NLM -STAT- MEDLINE -DCOM- 20090417 -LR - 20171116 -IS - 1535-6280 (Electronic) -IS - 0146-2806 (Linking) -VI - 34 -IP - 2 -DP - 2009 Feb -TI - Aldosterone and cardiovascular disease. -PG - 51-84 -LID - 10.1016/j.cpcardiol.2008.10.002 [doi] -AB - Aldosterone is an adrenal hormone that regulates sodium, fluid, and potassium - balance. Jerome Conn first described the syndrome of autonomous and excessive - aldosterone secretion or "primary aldosteronism." Contrary to the historical - belief, recent studies indicate that primary aldosteronism is a common cause of - hypertension with a prevalence of 5-10% among general hypertensive patients. - Various animal models have demonstrated that aldosterone in association with a - high salt diet results in target-organ inflammation and fibrosis. Similarly, - cross-sectional and observational human studies have demonstrated the association - of aldosterone with development and severity of hypertension, congestive heart - failure, coronary artery disease, chronic kidney disease, and metabolic syndrome. - Several interventional studies have also demonstrated the beneficial effects of - mineralocorticoid receptor antagonists in these disease processes, particularly - hypertension, heart failure, and post myocardial infarction, further supporting - the role of aldosterone in their pathogenesis. We review the role of aldosterone - in these various cardiovascular disease processes along with potential mechanisms - and treatment. -FAU - Gaddam, Krishna K -AU - Gaddam KK -FAU - Pimenta, Eduardo -AU - Pimenta E -FAU - Husain, Saima -AU - Husain S -FAU - Calhoun, David A -AU - Calhoun DA -LA - eng -GR - HL007457/HL/NHLBI NIH HHS/United States -GR - HL075614/HL/NHLBI NIH HHS/United States -GR - HL077100/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - Netherlands -TA - Curr Probl Cardiol -JT - Current problems in cardiology -JID - 7701802 -RN - 0 (Antihypertensive Agents) -RN - 0 (Cardiovascular Agents) -RN - 0 (Mineralocorticoid Receptor Antagonists) -RN - 4964P6T9RB (Aldosterone) -SB - IM -MH - Adrenalectomy -MH - Aldosterone/*metabolism -MH - Animals -MH - Antihypertensive Agents/therapeutic use -MH - Cardiovascular Agents/therapeutic use -MH - Cardiovascular Diseases/*etiology/metabolism/therapy -MH - Heart Failure/etiology/metabolism -MH - Humans -MH - Hyperaldosteronism/*complications/diagnosis/metabolism/therapy -MH - Hypertension/etiology/metabolism -MH - Kidney Diseases/etiology/metabolism -MH - Metabolic Syndrome/etiology/metabolism -MH - Mineralocorticoid Receptor Antagonists/therapeutic use -MH - Treatment Outcome -RF - 74 -EDAT- 2009/01/13 09:00 -MHDA- 2009/04/18 09:00 -CRDT- 2009/01/13 09:00 -PHST- 2009/01/13 09:00 [entrez] -PHST- 2009/01/13 09:00 [pubmed] -PHST- 2009/04/18 09:00 [medline] -AID - S0146-2806(08)00166-7 [pii] -AID - 10.1016/j.cpcardiol.2008.10.002 [doi] -PST - ppublish -SO - Curr Probl Cardiol. 2009 Feb;34(2):51-84. doi: 10.1016/j.cpcardiol.2008.10.002. - -PMID- 23140073 -OWN - NLM -STAT- MEDLINE -DCOM- 20121204 -LR - 20221207 -IS - 1049-510X (Print) -IS - 1049-510X (Linking) -VI - 22 -IP - 4 -DP - 2012 Autumn -TI - Review: Heart failure with preserved ejection fraction in African Americans. -PG - 432-8 -AB - Heart failure (HF) affects 5,700 000 people in the United States, with heart - failure with preserved ejection fraction (HFPEF) being responsible for between - 30%-50% of acute admissions. Epidemiological studies and HF registries have found - HFPEF patients to be older, hypertensive and to have a history of atrial - fibrillation. These findings, however, may not be fully applicable to African - Americans, as they have been poorly studied making up only a minority of the test - subjects. This review article is intended to discuss the pathophysiology and - epidemiology of HFPEF within African Americans, highlight the differences - compared to Caucasian populations and review current treatment guidelines. - Studies looking at African Americans in particular have shown them to be younger, - female and have worse diastolic dysfunction compared to Caucasian populations. - African Americans also have been shown to have a worse mortality outcome - especially in patients without coronary artery disease. The treatment of HFPEF is - primarily symptomatic with no survival benefit seen in randomized controlled - trials. Mechanisms postulated for the worse prognosis in African Americans with - HFPEF include: greater incidence of hypertension and diastolic dysfunction, - undefined race-driven genetic predispositions or relative resistance to - medications that treat HF in general. The biological predispositions may also be - compounded by inequality of healthcare access; something still felt to exist - today. Prospective studies and randomized controlled trials need to be conducted - with particular emphasis on African American populations to fully elucidate this - disease and to formulate race specific treatment outcomes for the future. -FAU - Shah, Sachil -AU - Shah S -AD - Internal Medicine, University of Miami-Miller School of Medicine Regional Campus, - 600 S. Dixie Highway, West Palm Beach, Florida, 33401, USA. - sachilshah@doctors.net.uk -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Ethn Dis -JT - Ethnicity & disease -JID - 9109034 -SB - IM -MH - Black or African American/*statistics & numerical data -MH - Genetic Predisposition to Disease/ethnology -MH - Heart Failure/*ethnology/genetics/*physiopathology -MH - Humans -MH - Prognosis -MH - Stroke Volume -MH - White People -EDAT- 2012/11/13 06:00 -MHDA- 2012/12/10 06:00 -CRDT- 2012/11/13 06:00 -PHST- 2012/11/13 06:00 [entrez] -PHST- 2012/11/13 06:00 [pubmed] -PHST- 2012/12/10 06:00 [medline] -PST - ppublish -SO - Ethn Dis. 2012 Autumn;22(4):432-8. - -PMID- 24093848 -OWN - NLM -STAT- MEDLINE -DCOM- 20131203 -LR - 20181202 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 166 -IP - 4 -DP - 2013 Oct -TI - Non-infarct-related artery revascularization during primary percutaneous coronary - intervention for ST-segment elevation myocardial infarction: a systematic review - and meta-analysis. -PG - 684-693.e1 -LID - S0002-8703(13)00513-9 [pii] -LID - 10.1016/j.ahj.2013.07.027 [doi] -AB - BACKGROUND: In patients with ST-elevation myocardial infarction (STEMI) and - multivessel disease, guidelines recommend infarct-related artery (IRA) only - intervention during primary percutaneous coronary intervention (PCI) except in - patients with hemodynamic instability. To assess the available evidence, we - performed a systematic review and meta-analysis comparing outcomes of non-IRA PCI - as an adjunct to primary PCI (same sitting PCI [SS-PCI]) with IRA only PCI - (IRA-PCI) in the setting of STEMI. METHODS AND RESULTS: A comprehensive search - identified 14 studies [11 cohort, 3 randomized controlled trials] comprising of - 35,239 patients. For cohort studies, patients undergoing SS-PCI had higher rate - of anterior infarction (48% vs. 45%, P = .04) and cardiogenic shock (11% vs. 9%, - P = .0001) at baseline compared with IRA-PCI. The primary composite end point of - death, myocardial infarction and revascularization was higher in the SS-PCI group - in the short term (OR, 1.63; CI, 1.12-2.37) and long term (OR, 1.60; CI, - 1.18-2.16). However, after excluding patients with shock, there was no difference - in primary endpoint for the short (OR, 1.33; CI, 0.67-2.63) and long term (OR, - 1.39; CI, 0.80-2.42) follow-up. In analyses limited to randomized controlled - trials, primary end point was similar during short term (OR, 0.79; CI, 0.19-3.28) - and significantly lower for SS-PCI group in the long term (OR, 0.55; CI, - 0.34-0.91). CONCLUSIONS: There is paucity of randomized data to guide management - of STEMI patients with multivessel disease. SS-PCI group in cohort studies has - higher baseline risk compared to IRA-PCI. The primary end point is higher for - SS-PCI in observational cohort studies but this difference did not persist after - exclusion of shock patients and for analysis limited to randomized controlled - trials. These findings underscore the need of a large randomized controlled trial - to guide therapy for a commonly encountered clinical situation. -CI - © 2013. -FAU - Bagai, Akshay -AU - Bagai A -AD - St. Michael's Hospital, Toronto, Canada. -FAU - Thavendiranathan, Paaladinesh -AU - Thavendiranathan P -FAU - Sharieff, Waseem -AU - Sharieff W -FAU - Al Lawati, Hatim A -AU - Al Lawati HA -FAU - Cheema, Asim N -AU - Cheema AN -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PT - Systematic Review -DEP - 20130920 -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -SB - IM -MH - Coronary Angiography -MH - Coronary Circulation/*physiology -MH - Coronary Vessels/*surgery -MH - *Electrocardiography -MH - Humans -MH - Intraoperative Period -MH - *Myocardial Infarction/diagnostic imaging/physiopathology/surgery -MH - Myocardial Revascularization/*methods -MH - Percutaneous Coronary Intervention/*methods -MH - Randomized Controlled Trials as Topic -MH - Treatment Outcome -EDAT- 2013/10/08 06:00 -MHDA- 2013/12/16 06:00 -CRDT- 2013/10/08 06:00 -PHST- 2012/12/05 00:00 [received] -PHST- 2013/07/16 00:00 [accepted] -PHST- 2013/10/08 06:00 [entrez] -PHST- 2013/10/08 06:00 [pubmed] -PHST- 2013/12/16 06:00 [medline] -AID - S0002-8703(13)00513-9 [pii] -AID - 10.1016/j.ahj.2013.07.027 [doi] -PST - ppublish -SO - Am Heart J. 2013 Oct;166(4):684-693.e1. doi: 10.1016/j.ahj.2013.07.027. Epub 2013 - Sep 20. - -PMID- 17239676 -OWN - NLM -STAT- MEDLINE -DCOM- 20070320 -LR - 20071115 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 153 -IP - 2 -DP - 2007 Feb -TI - Curriculum in cardiology: integrated diagnosis and management of diastolic heart - failure. -PG - 189-200 -AB - Among the general heart failure (HF) population, over half have diastolic HF - (DHF). The proportion of DHF increases with age, from 46% in patients younger - than 45 years to 59% in patients older than 85 years. The diagnosis of DHF is - made by the combination of signs and symptoms of HF with preserved systolic - function (left ventricular ejection fraction >50%), and evidence of diastolic - dysfunction obtained by echocardiographic Doppler examination, invasive - hemodynamic evaluation, or an elevation of serum B-type natriuretic peptide. The - most common risk factors for the development of diastolic dysfunction and DHF - include long-standing hypertension, older age, female sex, obesity, diabetes, - chronic kidney disease, and coronary artery disease. Acute decompensation occurs - in the setting of pressure overload, volume overload, or superimposed cardiac - ischemia. The cornerstones of in-hospital management include blood pressure and - volume control, heart rate control, and correction of precipitating factors. - Priorities in the outpatient clinic include optimal blood pressure control, - maintenance of euvolemia with minimal or no diuretics, and, potentially, use of - disease-modifying drugs including angiotensin-converting enzyme inhibitors, - angiotensin II receptor blockers, aldosterone receptor blockers, beta-blockers, - and digoxin. Long-term regression of left ventricular hypertrophy, improvement in - diastolic filling parameters, and sustained reductions in B-type natriuretic - peptide may be future treatment targets for this condition. -FAU - Chinnaiyan, Kavitha M -AU - Chinnaiyan KM -AD - Division of Cardiology, William Beaumont Hospital, Royal Oak, MI 48073, USA. -FAU - Alexander, Daniel -AU - Alexander D -FAU - Maddens, Michael -AU - Maddens M -FAU - McCullough, Peter A -AU - McCullough PA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -SB - IM -CIN - Am Heart J. 2007 Jul;154(1):e5; author reply e7. doi: 10.1016/j.ahj.2007.04.017. - PMID: 17584543 -MH - Diastole -MH - Heart Failure/*diagnosis/*drug therapy/physiopathology -MH - Humans -RF - 49 -EDAT- 2007/01/24 09:00 -MHDA- 2007/03/21 09:00 -CRDT- 2007/01/24 09:00 -PHST- 2006/08/02 00:00 [received] -PHST- 2006/10/23 00:00 [accepted] -PHST- 2007/01/24 09:00 [pubmed] -PHST- 2007/03/21 09:00 [medline] -PHST- 2007/01/24 09:00 [entrez] -AID - S0002-8703(06)00934-3 [pii] -AID - 10.1016/j.ahj.2006.10.022 [doi] -PST - ppublish -SO - Am Heart J. 2007 Feb;153(2):189-200. doi: 10.1016/j.ahj.2006.10.022. - -PMID- 19463373 -OWN - NLM -STAT- MEDLINE -DCOM- 20090611 -LR - 20140905 -IS - 1876-7605 (Electronic) -IS - 1936-8798 (Linking) -VI - 1 -IP - 6 -DP - 2008 Dec -TI - Pediatric cardiac interventions. -PG - 603-11 -LID - 10.1016/j.jcin.2008.07.007 [doi] -AB - The field of pediatric cardiac interventions has witnessed a dramatic increase in - the number and type of procedures performed. We review the most common procedures - performed in the catheter laboratory. Lesions are divided according to their - physiological characteristics into left-to-right shunting lesions (atrial septal - defect, patent ductus arteriosus, ventricular septal defect), right-to-left - shunting lesions (pulmonary stenosis, pulmonary atresia/intact ventricular - septum), right heart obstructive lesions (peripheral arterial pulmonic stenosis, - right ventricular outflow tract obstruction), and left heart obstructive lesions - (aortic valve stenosis, coarctation of the aorta). In addition, a miscellaneous - group of lesions is discussed. -FAU - Hijazi, Ziyad M -AU - Hijazi ZM -AD - Department of Pediatrics, Section of Cardiology, Rush University Medical Center, - Rush Center for Congenital and Structural Heart Disease, Chicago, Illinois 60637, - USA. zhijazi@rush.edu -FAU - Awad, Sawsan M -AU - Awad SM -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - JACC Cardiovasc Interv -JT - JACC. Cardiovascular interventions -JID - 101467004 -SB - IM -MH - Cardiac Catheterization/adverse effects/instrumentation/*methods -MH - Child -MH - Child, Preschool -MH - Cineangiography -MH - Coronary Angiography -MH - Coronary Circulation -MH - Echocardiography, Doppler, Color -MH - Equipment Design -MH - Female -MH - Heart Defects, Congenital/diagnosis/physiopathology/*therapy -MH - Hemodynamics -MH - Humans -MH - Infant -MH - Infant, Newborn -MH - Male -MH - *Radiography, Interventional -MH - Treatment Outcome -MH - *Ultrasonography, Interventional -RF - 91 -EDAT- 2009/05/26 09:00 -MHDA- 2009/06/12 09:00 -CRDT- 2009/05/26 09:00 -PHST- 2008/04/14 00:00 [received] -PHST- 2008/06/24 00:00 [revised] -PHST- 2008/07/27 00:00 [accepted] -PHST- 2009/05/26 09:00 [entrez] -PHST- 2009/05/26 09:00 [pubmed] -PHST- 2009/06/12 09:00 [medline] -AID - S1936-8798(08)00424-X [pii] -AID - 10.1016/j.jcin.2008.07.007 [doi] -PST - ppublish -SO - JACC Cardiovasc Interv. 2008 Dec;1(6):603-11. doi: 10.1016/j.jcin.2008.07.007. - -PMID- 17715104 -OWN - NLM -STAT- MEDLINE -DCOM- 20070918 -LR - 20161124 -IS - 1546-3141 (Electronic) -IS - 0361-803X (Linking) -VI - 189 -IP - 3 -DP - 2007 Sep -TI - Artifacts in ECG-synchronized MDCT coronary angiography. -PG - 581-91 -AB - OBJECTIVE: In MDCT coronary angiography, image artifacts are the major cause of - false-positive and false-negative interpretations regarding the presence of - coronary artery stenoses. Hence, it is important that observers reporting these - investigations are aware of the potential presence of image artifacts and that - these artifacts are recognized. CONCLUSION: The article explores the technical - causes for various artifacts in MDCT coronary angiography imaging and clinical - examples are given. -FAU - Kroft, L J M -AU - Kroft LJ -AD - Department of Radiology, C2S, Leiden University Medical Center, Albinusdreef 2, - 2333 ZA, Leiden, The Netherlands. l.j.m.kroft@lumc.nl -FAU - de Roos, A -AU - de Roos A -FAU - Geleijns, J -AU - Geleijns J -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - AJR Am J Roentgenol -JT - AJR. American journal of roentgenology -JID - 7708173 -SB - IM -MH - *Artifacts -MH - Coronary Angiography/*methods -MH - Coronary Stenosis/*diagnostic imaging -MH - Electrocardiography/*methods -MH - Humans -MH - *Movement -MH - Radiographic Image Enhancement/*methods -MH - Reproducibility of Results -MH - Sensitivity and Specificity -MH - Tomography, X-Ray Computed/instrumentation/*methods -RF - 50 -EDAT- 2007/08/24 09:00 -MHDA- 2007/09/19 09:00 -CRDT- 2007/08/24 09:00 -PHST- 2007/08/24 09:00 [pubmed] -PHST- 2007/09/19 09:00 [medline] -PHST- 2007/08/24 09:00 [entrez] -AID - 189/3/581 [pii] -AID - 10.2214/AJR.07.2138 [doi] -PST - ppublish -SO - AJR Am J Roentgenol. 2007 Sep;189(3):581-91. doi: 10.2214/AJR.07.2138. - -PMID- 22104612 -OWN - NLM -STAT- MEDLINE -DCOM- 20120427 -LR - 20171116 -IS - 1095-8673 (Electronic) -IS - 0022-4804 (Linking) -VI - 173 -IP - 2 -DP - 2012 Apr -TI - The role of hyaluronic acid in atherosclerosis and intimal hyperplasia. -PG - e63-72 -LID - 10.1016/j.jss.2011.09.025 [doi] -AB - Atherosclerosis is a chronic inflammatory condition of the blood vessel wall that - can lead to arterial narrowing and subsequent vascular compromise. Although there - are a variety of open and endovascular procedures used to alleviate the - obstructions caused by atherosclerotic plaque, blood vessel instrumentation - itself can lead to renarrowing of the vessel lumen through intimal hyperplasia, - wound contracture, or a combination of the two. While the cell types involved in - both atherosclerosis and vessel renarrowing after surgical intervention are - largely characterized, current research has shown that components of the - extracellular matrix are also important in the pathogenesis of the aforementioned - processes. One such component is hyaluronic acid (HA). The objective of this - review, therefore, is to examine the involvement of HA in these pathologic - processes. Literature on the structure and function of HA was reviewed, with - particular attention given to the role of HA in the processes of atherogenesis, - intimal hyperplasia, and wound contracture after blood vessel instrumentation. HA - interacts with vascular smooth muscle cells (VSMCs), endothelial cells (ECs), and - platelets to promote atherogenesis. In particular, VSMCs manufacture large - amounts of HA that form "cable-like" structures important for leukocyte adhesion - and rolling. Additionally, transmigration of leukocytes across the EC layer is - mediated by HA. Platelets cleave large molecules of HA into fragments that - up-regulate leukocyte production of chemokines and cytokines. HA also has a role - in both intimal hyperplasia and wound contracture, the two processes most - responsible for vessel renarrowing after vascular instrumentation. HA has a - complex, and sometimes conflicting, role in the pathologic processes of - atherogenesis and vessel wall renarrowing after surgical intervention. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Sadowitz, Benjamin -AU - Sadowitz B -AD - SUNY Upstate Medical University, Division of Vascular Surgery and Endovascular - Services, Syracuse, New York 13210, USA. -FAU - Seymour, Keri -AU - Seymour K -FAU - Gahtan, Vivian -AU - Gahtan V -FAU - Maier, Kristopher G -AU - Maier KG -LA - eng -PT - Journal Article -PT - Review -DEP - 20111011 -PL - United States -TA - J Surg Res -JT - The Journal of surgical research -JID - 0376340 -RN - 0 (Hyaluronan Receptors) -RN - 9004-61-9 (Hyaluronic Acid) -SB - IM -MH - Animals -MH - Atherosclerosis/*etiology/therapy -MH - Coronary Restenosis/*etiology -MH - Hyaluronan Receptors/metabolism -MH - Hyaluronic Acid/biosynthesis/chemistry/*physiology -MH - Hyperplasia/etiology -MH - Tunica Intima/pathology -EDAT- 2011/11/23 06:00 -MHDA- 2012/04/28 06:00 -CRDT- 2011/11/23 06:00 -PHST- 2011/06/03 00:00 [received] -PHST- 2011/08/19 00:00 [revised] -PHST- 2011/09/14 00:00 [accepted] -PHST- 2011/11/23 06:00 [entrez] -PHST- 2011/11/23 06:00 [pubmed] -PHST- 2012/04/28 06:00 [medline] -AID - S0022-4804(11)00751-7 [pii] -AID - 10.1016/j.jss.2011.09.025 [doi] -PST - ppublish -SO - J Surg Res. 2012 Apr;173(2):e63-72. doi: 10.1016/j.jss.2011.09.025. Epub 2011 Oct - 11. - -PMID- 20948503 -OWN - NLM -STAT- MEDLINE -DCOM- 20110303 -LR - 20151119 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 58 -IP - 5 -DP - 2010 Oct -TI - Paclitaxel-coated balloons - Survey of preclinical data. -PG - 567-82 -AB - Restenosis following interventions in the coronary or peripheral arteries - develops over weeks to months. In coronary arteries the restenosis rate has been - markedly reduced since the advent of drug-eluting stents. Non-stent-based methods - for local drug delivery enable restenosis inhibition without the need for stent - implantation, does not permanently change the structure of the vessel, are - repeatable, and seems to be applicable where drug-eluting stents provide - insufficient protection. Preclinical data indicate that short exposure of the - vessel wall to a lipophilic inhibitor of cell proliferation is sufficient for - preventing restenosis. Initial evidence to this effect emerged from an - investigation of paclitaxel embedded in a matrix that enhances the solubility and - release of the agent from the balloon coating as well as its transfer to the - vessel wall. Further corroborating data from preclinical and clinical studies - demonstrating a reduction in late lumen loss and lower restenosis rates led to - the market introduction of a variety of paclitaxel-coated angioplasty balloons. - The effectiveness of restenosis inhibition is not determined by the active agent - alone. Other factors that are crucial for the effectiveness and safety of - drug-coated angioplasty balloons are the formulation containing the agent and the - coating technique. In this review we first outline the development of - paclitaxel-coated balloons to then provide an overview of the preclinical results - obtained with different paclitaxel-coated balloons and finally compare these with - the outcome in patients. The article concludes with a short outlook on initial - results with a zotarolimus-coated angioplasty balloon. -FAU - Schnorr, B -AU - Schnorr B -AD - Department of Radiology, Experimental Radiology, Charité, University Hospital, - Berlin, Germany. beatrix.schnorr@charite.de -FAU - Kelsch, B -AU - Kelsch B -FAU - Cremers, B -AU - Cremers B -FAU - Clever, Y P -AU - Clever YP -FAU - Speck, U -AU - Speck U -FAU - Scheller, B -AU - Scheller B -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -RN - H4GXR80IZE (zotarolimus) -RN - P88XT4IS4D (Paclitaxel) -RN - W36ZG6FT64 (Sirolimus) -SB - IM -MH - *Angioplasty, Balloon, Coronary -MH - Coronary Restenosis/*prevention & control -MH - Drug Delivery Systems -MH - *Drug-Eluting Stents -MH - Humans -MH - Paclitaxel/*administration & dosage/*therapeutic use -MH - Sirolimus/administration & dosage/analogs & derivatives/therapeutic use -EDAT- 2010/10/16 06:00 -MHDA- 2011/03/04 06:00 -CRDT- 2010/10/16 06:00 -PHST- 2010/10/16 06:00 [entrez] -PHST- 2010/10/16 06:00 [pubmed] -PHST- 2011/03/04 06:00 [medline] -AID - R05103062 [pii] -PST - ppublish -SO - Minerva Cardioangiol. 2010 Oct;58(5):567-82. - -PMID- 20387549 -OWN - NLM -STAT- MEDLINE -DCOM- 20100429 -LR - 20110727 -IS - 0047-1852 (Print) -IS - 0047-1852 (Linking) -VI - 68 -IP - 4 -DP - 2010 Apr -TI - [Acute coronary syndrome-initiating factors]. -PG - 607-14 -AB - Acute coronary syndrome(ACS), including acute myocardial infarction and unstable - angina, is a clinical state induced by the thrombus formation following the - disruption of unstable atherosclerotic plaque. Recent studies have reported that - activated macrophages in the vulnerable plaques destabilize the fibrous cap by - the induction of protease such as matrix metalloproteinases. Also, macrophages - produce tissue factor and plasminogen-activator inhibitor type 1 those activate - thrombus formation following plaque rupture. On the other hand, coronary spasm - plays an important role in the pathogenesis of ACS especially in Japan. In this - article, we review related factors leading to plaque rupture and erosion in the - basic aspect. -FAU - Tsujita, Kenichi -AU - Tsujita K -AD - Department of Cardiovascular Medicine, Graduate School of Medical Sciences, - Kumamoto University. -FAU - Kaikita, Koichi -AU - Kaikita K -FAU - Soejima, Hirofumi -AU - Soejima H -FAU - Sugiyama, Seigo -AU - Sugiyama S -FAU - Ogawa, Hisao -AU - Ogawa H -LA - jpn -PT - English Abstract -PT - Journal Article -PT - Review -PL - Japan -TA - Nihon Rinsho -JT - Nihon rinsho. Japanese journal of clinical medicine -JID - 0420546 -RN - 0 (Cholesterol, LDL) -SB - IM -MH - Acute Coronary Syndrome/*etiology -MH - Blood Coagulation -MH - Cholesterol, LDL/metabolism -MH - Coronary Thrombosis/blood -MH - Fibrinolysis/physiology -MH - Humans -MH - Macrophages/physiology -MH - Oxidation-Reduction -MH - Thrombosis/complications -RF - 29 -EDAT- 2010/04/15 06:00 -MHDA- 2010/04/30 06:00 -CRDT- 2010/04/15 06:00 -PHST- 2010/04/15 06:00 [entrez] -PHST- 2010/04/15 06:00 [pubmed] -PHST- 2010/04/30 06:00 [medline] -PST - ppublish -SO - Nihon Rinsho. 2010 Apr;68(4):607-14. - -PMID- 19770793 -OWN - NLM -STAT- MEDLINE -DCOM- 20110301 -LR - 20181201 -IS - 1536-3686 (Electronic) -IS - 1075-2765 (Linking) -VI - 17 -IP - 6 -DP - 2010 Nov-Dec -TI - Safety and efficacy of prolonged use of unfractionated heparin after percutaneous - coronary intervention. -PG - 535-42 -LID - 10.1097/MJT.0b013e3181b63f05 [doi] -AB - The current guidelines for percutaneous coronary intervention do not address the - prolonged postprocedural use of unfractionated heparin (UFH) to prevent acute - occlusion. However, recently published small studies have yielded mixed results, - leaving the question unanswered. Hence, we performed a meta-analysis of the - existing evidence to assess the safety and efficacy of prolonged infusion of UFH - after percutaneous coronary intervention. A systematic review of literature - revealed seven studies involving 2412 patients. End points analyzed were ischemic - complications (acute closure, myocardial infarction, and repeat - revascularization) and major vascular complications (hematoma, arteriovenous - fistula, pseudoaneurysm, and retroperitoneal bleed). Because the studies were - homogenous for outcomes, combined relative risks across all the studies and the - 95% confidence intervals were computed using the Mantel-Haenszel fixed-effect - model. A two-sided alpha error <0.05 was considered to be statistically - significant. There were no significant differences in patient demographics - between both groups. Compared with placebo, the risk of major vascular - complication was significantly higher in patients getting postprocedural UFH for - prolonged hours (relative risk, 2.24; confidence interval, 1.68-3.48; P = 0.001). - However, the risk of ischemic complications was similar in both groups (relative - risk, 0.95; confidence interval, 0.46-1.96; P = 0.89). The meta-analysis suggests - that routine infusion of UFH after uncomplicated percutaneous coronary - intervention may result in increased vascular complications without any reduction - in incidence of ischemic complications. -FAU - Singh, Param Puneet -AU - Singh PP -AD - Section of Cardiology, Department of Internal Medicine, Chicago Medical - School/Rosalind Franklin University of Medicine and Science, North Chicago, IL - 60064, USA. drparamsingh@gmail.com -FAU - Arora, Rohit -AU - Arora R -FAU - Singh, Mukesh -AU - Singh M -FAU - Bedi, Updesh Singh -AU - Bedi US -FAU - Adigopula, Sasikanth -AU - Adigopula S -FAU - Singh, Sarabjeet -AU - Singh S -FAU - Bhuriya, Rohit -AU - Bhuriya R -FAU - Molnar, Janos -AU - Molnar J -FAU - Khosla, Sandeep -AU - Khosla S -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -PL - United States -TA - Am J Ther -JT - American journal of therapeutics -JID - 9441347 -RN - 0 (Anticoagulants) -RN - 9005-49-6 (Heparin) -SB - IM -MH - *Angioplasty, Balloon, Coronary -MH - Anticoagulants/*administration & dosage/*adverse effects/therapeutic use -MH - Coronary Occlusion/prevention & control -MH - Endpoint Determination -MH - Heparin/*administration & dosage/*adverse effects/therapeutic use -MH - Humans -MH - Treatment Outcome -EDAT- 2009/09/23 06:00 -MHDA- 2011/03/02 06:00 -CRDT- 2009/09/23 06:00 -PHST- 2009/09/23 06:00 [entrez] -PHST- 2009/09/23 06:00 [pubmed] -PHST- 2011/03/02 06:00 [medline] -AID - 10.1097/MJT.0b013e3181b63f05 [doi] -PST - ppublish -SO - Am J Ther. 2010 Nov-Dec;17(6):535-42. doi: 10.1097/MJT.0b013e3181b63f05. - -PMID- 19519354 -OWN - NLM -STAT- MEDLINE -DCOM- 20090902 -LR - 20190911 -IS - 1873-5592 (Electronic) -IS - 1389-4501 (Linking) -VI - 10 -IP - 6 -DP - 2009 Jun -TI - Deciphering dual antiplatelet therapy in the era of drug-eluting coronary stents. -PG - 519-29 -AB - The recently described complication of late and very late stent thrombosis with - coronary stents has raised the question of when is it safe to stop antiplatelet - therapy in the era of drug eluting stents? With several million patients having - already had coronary stents implanted worldwide, the importance of an - appreciation of stent thrombosis is not only critical to the cardiologist but - also surgeon, physician, dentist and other specialists that perform procedures on - patients which require with-holding antiplatelet agents. Currently there is great - concern amongst medical professionals on how to manage this group of patients in - the absence of clear guidelines. This article reviews the current data on - coronary stents, in-stent restenosis and stent thrombosis and role of - antiplatelet medication post percutaneous coronary intervention (PCI) to provide - a concise and clear algorithm for managing perioperative antiplatelet therapy in - patients having undergone recent PCI. The algorithm encourages a - multidisciplinary approach and is based on the surgical bleeding risk, operative - risk of adverse cardiac events and stent thrombosis risk to guide safe practice. - Challenging areas including aspirin and clopidogrel hypersensitivity, clopidogrel - resistance and concomitant vitamin K antagonist therapy are also addressed. -FAU - Bell, Brendan -AU - Bell B -AD - The Prince Charles Hospital, Brisbane, Queensland, Australia. - brendanbell77@hotmail.com -FAU - Walters, Darren -AU - Walters D -FAU - Spaulding, Christian -AU - Spaulding C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Drug Targets -JT - Current drug targets -JID - 100960531 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 5Q7ZVV76EI (Warfarin) -SB - IM -MH - Coronary Thrombosis/*prevention & control -MH - Drug Hypersensitivity -MH - Drug Resistance -MH - Drug Therapy, Combination -MH - Drug-Eluting Stents/*adverse effects -MH - Graft Occlusion, Vascular/prevention & control -MH - Humans -MH - Platelet Aggregation Inhibitors/administration & dosage/adverse - effects/*therapeutic use -MH - Warfarin/therapeutic use -RF - 83 -EDAT- 2009/06/13 09:00 -MHDA- 2009/09/03 06:00 -CRDT- 2009/06/13 09:00 -PHST- 2009/06/13 09:00 [entrez] -PHST- 2009/06/13 09:00 [pubmed] -PHST- 2009/09/03 06:00 [medline] -AID - 10.2174/138945009788488413 [doi] -PST - ppublish -SO - Curr Drug Targets. 2009 Jun;10(6):519-29. doi: 10.2174/138945009788488413. - -PMID- 16613189 -OWN - NLM -STAT- MEDLINE -DCOM- 20060525 -LR - 20151119 -IS - 0047-1852 (Print) -IS - 0047-1852 (Linking) -VI - 64 -IP - 4 -DP - 2006 Apr -TI - [Technical evolution of the stent]. -PG - 715-20 -AB - Percutaneous coronary intervention has been hampered by restenosis since its - inception. Many research projects including the use of various devices and - systemic drug administration have shown disappointing results. Recently, the - advent of drug-eluting stents has reduced incidence of restenosis compared with - bare metal stents. This article provides an overview of the developments of - drug-eluting stents, their clinical impact on the treatment of acute coronary - syndrome, and their future perspectives. -FAU - Tanabe, Kengo -AU - Tanabe K -AD - Division of Cardiology, Mitsui Memorial Hospital. -LA - jpn -PT - English Abstract -PT - Journal Article -PT - Review -PL - Japan -TA - Nihon Rinsho -JT - Nihon rinsho. Japanese journal of clinical medicine -JID - 0420546 -RN - P88XT4IS4D (Paclitaxel) -RN - W36ZG6FT64 (Sirolimus) -SB - IM -MH - Angina, Unstable/*therapy -MH - Animals -MH - Clinical Trials as Topic -MH - Coronary Restenosis/prevention & control -MH - Drug Delivery Systems -MH - Humans -MH - Myocardial Infarction/*therapy -MH - Paclitaxel/*administration & dosage -MH - Prognosis -MH - Sirolimus/*administration & dosage -MH - *Stents -MH - Syndrome -RF - 13 -EDAT- 2006/04/15 09:00 -MHDA- 2006/05/26 09:00 -CRDT- 2006/04/15 09:00 -PHST- 2006/04/15 09:00 [pubmed] -PHST- 2006/05/26 09:00 [medline] -PHST- 2006/04/15 09:00 [entrez] -PST - ppublish -SO - Nihon Rinsho. 2006 Apr;64(4):715-20. - -PMID- 22723537 -OWN - NLM -STAT- MEDLINE -DCOM- 20120830 -LR - 20211021 -IS - 1748-880X (Electronic) -IS - 0007-1285 (Print) -IS - 0007-1285 (Linking) -VI - 84 Spec No 3 -IP - Spec Iss 3 -DP - 2011 Dec -TI - Right heart on multidetector CT. -PG - S306-23 -LID - 10.1259/bjr/59278996 [doi] -AB - Right ventricular function plays an integral role in the pathogenesis and outcome - of many cardiovascular diseases. Imaging the right ventricle has long been a - challenge because of its complex geometry. In recent years there has been a - tremendous expansion in multidetector row CT (MDCT) and its cardiac applications. - By judicious modification of contrast medium protocol, it is possible to achieve - good opacification of the right-sided cardiac chambers, thereby paving the way - for exploring the overshadowed right heart. This article will describe the key - features of right heart anatomy, review MDCT acquisition techniques, elaborate - the various morphological and functional information that can be obtained, and - illustrate some important clinical conditions associated with an abnormal right - heart. -FAU - Gopalan, D -AU - Gopalan D -AD - Department of Radiology, Papworth Hospital NHS Trust, Papworth Everard, - Cambridge, UK. deepa.gopalan@btopenworld.com -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Br J Radiol -JT - The British journal of radiology -JID - 0373125 -SB - IM -MH - Aneurysm/diagnostic imaging -MH - Coronary Angiography -MH - Heart/anatomy & histology/*diagnostic imaging -MH - Heart Defects, Congenital/diagnostic imaging -MH - Heart Valve Diseases/diagnostic imaging -MH - Heart Ventricles/anatomy & histology/diagnostic imaging -MH - Humans -MH - Hypertension, Pulmonary/diagnostic imaging -MH - Multidetector Computed Tomography/*methods -MH - Pulmonary Heart Disease/diagnostic imaging -MH - Ventricular Dysfunction, Right/diagnostic imaging -MH - Ventricular Function, Right/physiology -PMC - PMC3473916 -EDAT- 2012/06/29 06:00 -MHDA- 2012/08/31 06:00 -PMCR- 2012/12/01 -CRDT- 2012/06/23 06:00 -PHST- 2012/06/23 06:00 [entrez] -PHST- 2012/06/29 06:00 [pubmed] -PHST- 2012/08/31 06:00 [medline] -PHST- 2012/12/01 00:00 [pmc-release] -AID - 84/Special_Issue_3/S306 [pii] -AID - D10869 [pii] -AID - 10.1259/bjr/59278996 [doi] -PST - ppublish -SO - Br J Radiol. 2011 Dec;84 Spec No 3(Spec Iss 3):S306-23. doi: - 10.1259/bjr/59278996. - -PMID- 19662964 -OWN - NLM -STAT- MEDLINE -DCOM- 20090917 -LR - 20090810 -IS - 1547-4127 (Print) -VI - 19 -IP - 2 -DP - 2009 May -TI - Combined cardiac and lung volume reduction surgery. -PG - 217-21, viii-ix -LID - 10.1016/j.thorsurg.2009.04.001 [doi] -AB - Coronary artery disease is prevalent in patients who have severe emphysema and - who are being considered for lung volume reduction surgery (LVRS). Significant - valvular heart diseases may also coexist in these patients. Few thoracic surgeons - have performed LVRS in patients who have severe cardiac diseases. Conversely, few - cardiac surgeons have been willing to undertake major cardiac surgery in patients - who have severe emphysema. This report reviews the evidence regarding combined - cardiac surgery and LVRS to determine the optimal management strategy for - patients who have severe emphysema and who are suitable for LVRS, but who also - have coexisting significant cardiac diseases that are operable. -FAU - Choong, Cliff K -AU - Choong CK -AD - Papworth Hospital NHS Foundation Trust and Department of Surgery, The University - of Cambridge, Cambridge, UK. cliffchoong@hotmail.com -FAU - Schmid, Ralph A -AU - Schmid RA -FAU - Miller, Daniel L -AU - Miller DL -FAU - Smith, Julian A -AU - Smith JA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Thorac Surg Clin -JT - Thoracic surgery clinics -JID - 101198195 -SB - IM -MH - *Cardiac Surgical Procedures -MH - Heart Diseases/diagnosis/etiology/*surgery -MH - Humans -MH - Patient Selection -MH - *Pneumonectomy -MH - Pulmonary Emphysema/complications/diagnosis/*surgery -MH - Treatment Outcome -RF - 15 -EDAT- 2009/08/11 09:00 -MHDA- 2009/09/18 06:00 -CRDT- 2009/08/11 09:00 -PHST- 2009/08/11 09:00 [entrez] -PHST- 2009/08/11 09:00 [pubmed] -PHST- 2009/09/18 06:00 [medline] -AID - S1547-4127(09)00014-0 [pii] -AID - 10.1016/j.thorsurg.2009.04.001 [doi] -PST - ppublish -SO - Thorac Surg Clin. 2009 May;19(2):217-21, viii-ix. doi: - 10.1016/j.thorsurg.2009.04.001. - -PMID- 23176211 -OWN - NLM -STAT- MEDLINE -DCOM- 20131114 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 19 -IP - 17 -DP - 2013 -TI - Gene polymorphism of angiotensin II type 1 and type 2 receptors. -PG - 2996-3001 -AB - Renin-angiotensin system (RAS) plays a key role in pathogenesis of cardiovascular - disease and in the responsiveness for various types of medications. A large - number of genetic investigations have been carried out to examine the association - between gene variants of RAS and predisposition to cardiovascular diseases, such - as hypertension, coronary artery disease and stroke. Even though the major - results were obtained from genetic association studies of angiotensinogen or - angiotensin converting enzyme, unique findings were also elucidated from - investigations concerning single nucleotide polymorphisms (SNPs) of 2 types of - angioteinsin II receptor genes denoted as AGTR1 and AGTR2. Both genes have many - SNPs in the coding and its flanking regions but most of the studies used A1166C - polymorphism of AGTR1 and G1675A polymorphism of AGTR2. In the subjects with - C1166 allele of AGTR1, several investigations reported increased risk for - coronary artery disease, ischemic stroke, heart failure and end-stage renal - disease but not for hypertension. Interestingly, a few papers pointed out the - possibility that A1166C modulates the efficacy of RAS inhibitors. In the genetic - analysis of AGTR2, G1675 allele carriers had increased risk for left ventricular - hypertrophy, renal insufficiency and modulated hemodynamic response to RAS - inhibitors. In this review, we summarized previous investigations concerning the - genetic aspects of AGTR1 and AGTR2 to consider the clinical utility of SNPs of - these receptors. -FAU - Katsuya, Tomohiro -AU - Katsuya T -AD - Katsuya Clinic, Department of Clinical Gene Therapy, Osaka University Graduate - School of Medicine, 2-17-21 Nanamatsu-cho, Amagasaki, Hyogo 660-0052, Japan. - tkatsuya@iris.eonet.ne.jp -FAU - Morishita, Ryuichi -AU - Morishita R -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Receptor, Angiotensin, Type 1) -RN - 0 (Receptor, Angiotensin, Type 2) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/etiology/genetics -MH - Humans -MH - Hypertension/genetics -MH - Kidney Diseases/etiology/genetics -MH - *Polymorphism, Single Nucleotide -MH - Receptor, Angiotensin, Type 1/*genetics -MH - Receptor, Angiotensin, Type 2/*genetics -EDAT- 2012/11/28 06:00 -MHDA- 2013/11/15 06:00 -CRDT- 2012/11/27 06:00 -PHST- 2012/10/02 00:00 [received] -PHST- 2012/11/20 00:00 [accepted] -PHST- 2012/11/27 06:00 [entrez] -PHST- 2012/11/28 06:00 [pubmed] -PHST- 2013/11/15 06:00 [medline] -AID - CPD-EPUB-20121121-3 [pii] -AID - 10.2174/1381612811319170004 [doi] -PST - ppublish -SO - Curr Pharm Des. 2013;19(17):2996-3001. doi: 10.2174/1381612811319170004. - -PMID- 19144665 -OWN - NLM -STAT- MEDLINE -DCOM- 20090528 -LR - 20091119 -IS - 1753-9447 (Print) -IS - 1753-9447 (Linking) -VI - 3 -IP - 2 -DP - 2009 Apr -TI - Advances in the prevention of sudden cardiac death in the young. -PG - 145-55 -LID - 10.1177/1753944708100181 [doi] -AB - Sudden cardiac death (SCD) is a tragic and devastating complication of a number - of cardiovascular diseases. Although coronary artery disease accounts for a - majority of these deaths across all ages, many other aetiologies contribute to - this problem when it occurs in the young (age < or = 35 years), where coronary - artery disease is far less common. Specifically, genetic heart disorders are an - important cause of SCD in the young. While pharmacological therapies have made - some impact on prevention of SCD, the introduction of implantable - cardioverter-defibrillator (ICD) therapy has been the single major advance in the - prevention of SCD in the young. In addition, the awareness that most causes of - SCD in the young are inherited, means family screening of relatives of young SCD - victims allows identification of previously unrecognised at-risk individuals - thereby enabling prevention of SCD in relatives. The role of genetic testing, - both in living affected individuals and in the setting of a 'molecular autopsy', - is emerging as a key factor in early diagnosis of an underlying cardiovascular - genetic disorder. Understanding the genetic basis of SCD, investigating the - molecular mechanisms that lead from the gene defect to the clinical phenotype, - and elucidating the specific environmental triggers for SCD, will most likely - lead to further key improvements in the prevention of SCD in the young. -FAU - Shephard, Rhian -AU - Shephard R -AD - Signal Transduction Group, Centenary Institute, Sydney, Australia - r.shephard@centenary.org.au -FAU - Semsarian, Christopher -AU - Semsarian C -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090114 -PL - England -TA - Ther Adv Cardiovasc Dis -JT - Therapeutic advances in cardiovascular disease -JID - 101316343 -SB - IM -MH - Adult -MH - Cardiomyopathy, Hypertrophic/epidemiology/genetics -MH - Causality -MH - Comorbidity -MH - Death, Sudden, Cardiac/epidemiology/*prevention & control -MH - Genetic Predisposition to Disease/epidemiology -MH - Genetic Testing -MH - Humans -MH - Long QT Syndrome/epidemiology/genetics -MH - Pedigree -RF - 57 -EDAT- 2009/01/16 09:00 -MHDA- 2009/05/29 09:00 -CRDT- 2009/01/16 09:00 -PHST- 2009/01/16 09:00 [entrez] -PHST- 2009/01/16 09:00 [pubmed] -PHST- 2009/05/29 09:00 [medline] -AID - 1753944708100181 [pii] -AID - 10.1177/1753944708100181 [doi] -PST - ppublish -SO - Ther Adv Cardiovasc Dis. 2009 Apr;3(2):145-55. doi: 10.1177/1753944708100181. - Epub 2009 Jan 14. - -PMID- 18378336 -OWN - NLM -STAT- MEDLINE -DCOM- 20090210 -LR - 20151119 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 129 -IP - 1 -DP - 2008 Sep 16 -TI - BNP or NTproBNP? A clinician's perspective. -PG - 5-14 -LID - 10.1016/j.ijcard.2007.12.093 [doi] -AB - Existing literature on two natriuretic peptides--B-type natriuretic peptide (BNP) - and amino terminal pro-brain natriuretic peptide (NTproBNP)--is overwhelming. - Both peptides are acknowledged markers for cardiac dysfunction. Most of the - sources present data on either BNP or NTproBNP making the comparison difficult. - This paper focuses on reviewing studies directly comparing two peptides in the - setting of chronic and acute heart failure (HF) and coronary artery disease. Many - concomitant diseases influence these two peptides to varying extent. These - characteristics should be taken into consideration when interpreting results. For - most practical purposes, BNP and NTproBNP are interchangeable, and can be used - based on local preferences and availability. NTproBNP seems to be more - advantageous for diagnosing mild HF or asymptomatic left ventricular dysfunction. -FAU - Steiner, Johannes -AU - Steiner J -AD - University of South Florida, United States. -FAU - Guglin, Maya -AU - Guglin M -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -DEP - 20080418 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Biomarkers) -RN - 0 (Peptide Fragments) -RN - 0 (Protein Precursors) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Acute Disease -MH - Biomarkers/blood -MH - Chronic Disease -MH - Heart Failure/blood/diagnosis -MH - Humans -MH - Natriuretic Peptide, Brain/*blood/physiology -MH - Peptide Fragments/*blood/physiology -MH - Protein Precursors/*blood/physiology -MH - Ventricular Dysfunction, Left/blood/diagnosis -RF - 107 -EDAT- 2008/04/02 09:00 -MHDA- 2009/02/12 09:00 -CRDT- 2008/04/02 09:00 -PHST- 2007/10/11 00:00 [received] -PHST- 2007/12/27 00:00 [revised] -PHST- 2007/12/29 00:00 [accepted] -PHST- 2008/04/02 09:00 [pubmed] -PHST- 2009/02/12 09:00 [medline] -PHST- 2008/04/02 09:00 [entrez] -AID - S0167-5273(08)00154-X [pii] -AID - 10.1016/j.ijcard.2007.12.093 [doi] -PST - ppublish -SO - Int J Cardiol. 2008 Sep 16;129(1):5-14. doi: 10.1016/j.ijcard.2007.12.093. Epub - 2008 Apr 18. - -PMID- 18537602 -OWN - NLM -STAT- MEDLINE -DCOM- 20080731 -LR - 20191110 -IS - 1871-529X (Print) -IS - 1871-529X (Linking) -VI - 8 -IP - 2 -DP - 2008 Jun -TI - Diabetic heart and the cardiovascular surgeon. -PG - 147-52 -AB - The importance of diabetes mellitus (diabetes) as a cause of mortality and - morbidity is well known. The number of patients increases alongside aging of the - population and increase in the prevalence of obesity and sedentary life style. - Diabetes affects approximately 8% of the USA population. Type I - (insulin-dependent) diabetes occurs in 20% of cases, and type II - (insulin-independent or maturity onset) diabetes occurs in 80% of the diabetic - population diabetes mellitus type II is preceded by longstanding asymptomatic - hyperglycemia, which accounts for the development of long-term diabetic - complications. The main macrovascular complications for which diabetes has been a - well established risk factor throughout the cardiovascular system, are: coronary - artery disease (CAD), peripheral vascular disease (PVD), increased intima-media - thickness (IMT) and stroke. Considering the cardiovascular surgeon, diabetes is - associated with an increased rate of early and late complications following - coronary artery bypass grafting. Diabetic patients have also been known to have - an increased incidence of complications after elective major vascular surgery - such as carotid endarterectomy (CEA) and leg amputations due to PVD. - Cardiovascular surgeons frequently treat diabetic patients either because - diabetes is incidental to another disease requiring surgery, or due to - diabetes-related complication such as occlusive vascular disease, neuropathy or - infection. Approximately 50% of diabetics undergo one,or more operations during - their lifetime. This paper reviews the relationship between diabetic patients and - their cardiovascular surgeons. In order to understand this relationship, one must - first examine the underlying mechanisms by which hyperglycemia causes hazardous - pre and post operative consequences. Then, one must examine the existing evidence - of how diabetes correlates with these cardiovascular consequences, followed by - the need for multidisciplinary team work which helps the surgeon to cope with - diabetic patients. -FAU - Yosefy, Chaim -AU - Yosefy C -AD - Cardiology Department, Barzilai Medical Centre Campus, Ben-Gurion University, - Ashkelon, Israel. yosefy@barzi.health.gov.il -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Cardiovasc Hematol Disord Drug Targets -JT - Cardiovascular & hematological disorders drug targets -JID - 101269160 -SB - IM -MH - Cardiovascular Diseases/etiology/*surgery -MH - Cardiovascular Surgical Procedures/methods -MH - Diabetes Complications/surgery -MH - Diabetes Mellitus, Type 2/*complications -MH - Female -MH - Humans -MH - Hyperglycemia/complications/physiopathology -MH - Male -MH - Patient Care Team -MH - *Physician-Patient Relations -MH - Risk Factors -RF - 58 -EDAT- 2008/06/10 09:00 -MHDA- 2008/08/01 09:00 -CRDT- 2008/06/10 09:00 -PHST- 2008/06/10 09:00 [pubmed] -PHST- 2008/08/01 09:00 [medline] -PHST- 2008/06/10 09:00 [entrez] -AID - 10.2174/187152908784533694 [doi] -PST - ppublish -SO - Cardiovasc Hematol Disord Drug Targets. 2008 Jun;8(2):147-52. doi: - 10.2174/187152908784533694. - -PMID- 18091662 -OWN - NLM -STAT- MEDLINE -DCOM- 20080228 -LR - 20101118 -IS - 0391-1977 (Print) -IS - 0391-1977 (Linking) -VI - 32 -IP - 4 -DP - 2007 Dec -TI - Heart disease in Turner syndrome. -PG - 245-61 -AB - Turner syndrome (TS) is a relatively common disorder of female development caused - by loss of all or part of one sex chromosome. Because short stature and premature - ovarian failure are cardinal features of the syndrome, pediatric endocrinologists - have taken the lead in care for these girls. Congenital cardiovascular disease - affects approximately 50% of individuals and is the major cause of premature - mortality in adults. Unfortunately, teenage girls are often lost to follow up - after discharge from pediatric clinic. This review describes the spectrum of - cardiovascular defects in TS with emphasis on identifying patients at risk for - aortic dissection/rupture. Updated consensus guidelines for cardiac screening and - care are reviewed and genetic pathways implicated in Turner cardiovascular - disease, including premature coronary artery disease, are discussed. This - material is of particular importance because cardiac care for adults with TS - appears seriously deficient at present. -FAU - Bondy, C A -AU - Bondy CA -AD - Developmental Endocrinology Branch, National Institute of Child Health and Human - Development, National Institutes of Health, Bethesda, MD 20892, USA. - bondyc@mail.nih.gov -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Endocrinol -JT - Minerva endocrinologica -JID - 8406505 -RN - 12629-01-5 (Human Growth Hormone) -SB - IM -MH - Adolescent -MH - Adult -MH - Aortic Aneurysm/genetics/prevention & control -MH - Aortic Rupture/genetics/prevention & control -MH - *Body Height -MH - Cardiovascular Diseases/*congenital/*genetics/pathology -MH - Child -MH - *Chromosomes, Human, X -MH - Female -MH - Heart Defects, Congenital/*genetics -MH - Human Growth Hormone/metabolism -MH - Humans -MH - Mass Screening -MH - Population Surveillance -MH - Primary Ovarian Insufficiency/genetics -MH - Puberty -MH - Turner Syndrome/*complications/genetics -RF - 69 -EDAT- 2007/12/20 09:00 -MHDA- 2008/02/29 09:00 -CRDT- 2007/12/20 09:00 -PHST- 2007/12/20 09:00 [pubmed] -PHST- 2008/02/29 09:00 [medline] -PHST- 2007/12/20 09:00 [entrez] -PST - ppublish -SO - Minerva Endocrinol. 2007 Dec;32(4):245-61. - -PMID- 18294473 -OWN - NLM -STAT- MEDLINE -DCOM- 20080313 -LR - 20231024 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 155 -IP - 3 -DP - 2008 Mar -TI - Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of - acute myocardial infarction. -PG - 408-17 -LID - 10.1016/j.ahj.2007.11.008 [doi] -AB - Apical ballooning syndrome (ABS) is a unique reversible cardiomyopathy that is - frequently precipitated by a stressful event and has a clinical presentation that - is indistinguishable from a myocardial infarction. We review the best evidence - regarding the pathophysiology, clinical features, investigation, and management - of ABS. The incidence of ABS is estimated to be 1% to 2% of patients presenting - with an acute myocardial infarction. The pathophysiology remains unknown, but - catecholamine mediated myocardial stunning is the most favored explanation. Chest - pain and dyspnea are the typical presenting symptoms. Transient ST elevation may - be present on the electrocardiogram, and a small rise in cardiac troponin T is - invariable. Typically, there is hypokinesis or akinesis of the mid and apical - segments of the left ventricle with sparing of the basal systolic function - without obstructive coronary lesions. Supportive treatment leads to spontaneous - rapid recovery in nearly all patients. The prognosis is excellent, and a - recurrence occurs in <10% of patients. Apical ballooning syndrome should be - included in the differential diagnosis of patients with an apparent acute - coronary syndrome with left ventricular regional wall motion abnormality and - absence of obstructive coronary artery disease, especially in the setting of a - stressful trigger. -FAU - Prasad, Abhiram -AU - Prasad A -AD - The Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo - Clinic and Mayo Foundation, Rochester, MN 55905, USA. prasad.abhiram@mayo.edu -FAU - Lerman, Amir -AU - Lerman A -FAU - Rihal, Charanjit S -AU - Rihal CS -LA - eng -PT - Journal Article -PT - Review -DEP - 20080131 -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -RN - 0 (Biomarkers) -RN - 0 (Troponin T) -SB - IM -CIN - Am Heart J. 2008 Sep;156(3):e31. doi: 10.1016/j.ahj.2008.06.016. PMID: 18760115 -CIN - Am Heart J. 2008 Sep;156(3):e33. doi: 10.1016/j.ahj.2008.06.021. PMID: 18760116 -MH - Biomarkers/blood -MH - Coronary Angiography/*methods -MH - Diagnosis, Differential -MH - *Electrocardiography -MH - Gated Blood-Pool Imaging/*methods -MH - Humans -MH - Myocardial Infarction/*diagnosis -MH - Syndrome -MH - Takotsubo Cardiomyopathy/blood/*diagnosis/physiopathology -MH - Troponin T/*blood -RF - 82 -EDAT- 2008/02/26 09:00 -MHDA- 2008/03/14 09:00 -CRDT- 2008/02/26 09:00 -PHST- 2007/09/26 00:00 [received] -PHST- 2007/11/02 00:00 [accepted] -PHST- 2008/02/26 09:00 [pubmed] -PHST- 2008/03/14 09:00 [medline] -PHST- 2008/02/26 09:00 [entrez] -AID - S0002-8703(07)00914-3 [pii] -AID - 10.1016/j.ahj.2007.11.008 [doi] -PST - ppublish -SO - Am Heart J. 2008 Mar;155(3):408-17. doi: 10.1016/j.ahj.2007.11.008. Epub 2008 Jan - 31. - -PMID- 18088046 -OWN - NLM -STAT- MEDLINE -DCOM- 20080205 -LR - 20091111 -IS - 0370-8179 (Print) -IS - 0370-8179 (Linking) -VI - 135 -IP - 9-10 -DP - 2007 Sep-Oct -TI - [Diabetic cardiomyopathy: old disease or new entity?]. -PG - 576-82 -AB - Cardiovascular manifestation of diabetes has remarkable therapeutic and - prognostic implications. Diabetic cardiomyopathy is a distinct heart muscle - disease in patients with well-controlled diabetes mellitus that cannot be - ascribed to coronary artery disease, hypertension or any other known cardiac - disease. It is characterized by left ventricular diastolic dysfunction that can - be detected in 52-60% of well-controlled type II diabetic subjects using - contemporary Doppler techniques. Pathophysiologically, hyperglycaemia causes - myocardial necrosis and fibrosis, as well as the increase of myocardial free - radicals and oxidants, which decrease nitric oxide levels, worsen the endothelial - function and induce myocardial inflammation. Insulin resistance with - hyperinsulinaemia and decreased insulin sensitivity are responsible for left - ventricular hypertrophy. Clinical manifestations of diabetic cardiomyopathy are - dispnoea, arrhythmias, atypical chest pain or dizziness. The treatment of - diabetic cardiomopathy should be initiated as early as diastolic dysfunction is - identified. Various therapeutic options include improving diabetic control with - both diet and drugs (metformin and thiazolidinediones), use of ACE inhibitors, - beta blockers and calcium channel blockers. Daily physical activity and reduction - in body mass index may improve glucose homeostasis by reducing the - glucose/insulin ratio, and the increase of both insulin sensitivity and glucose - oxidation by the skeletal and cardiac muscles. Metformin and thiazolidinendiones - are used to treat insulin resistance, but have different mechanisms of action. - Metformin reduces free fatty amino acids effluvium from fat cells, thereby - suppressing hepatic glucose production and indirectly improving peripheral - insulin sensitivity and the endothelial function. In contrast, thiazolidinediones - improve peripheral insulin sensitivity by reducing circulating free fatty amino - acids, but also increasing production of adiponectin, which improves insulin - sensitivity. Beta-adrenoceptor blocking agents are effective in preventing or - reversing myocardial dilatation and remodelling, while ACE inhibitors facilitate - blood flow through microcirculation in coronary vascular bed, fat and skeletal - muscle, as well as improve insulin action at the cellular level. -FAU - Seferović, Petar M -AU - Seferović PM -FAU - Lalić, Nebojsa M -AU - Lalić NM -FAU - Seferović, Jelena P -AU - Seferović JP -FAU - Jotić, Aleksandra -AU - Jotić A -FAU - Lalić, Katarina -AU - Lalić K -FAU - Ristić, Arsen D -AU - Ristić AD -FAU - Simeunović, Dejan -AU - Simeunović D -FAU - Radovanović, Gorica -AU - Radovanović G -FAU - Vujisić-Tesić, Bosiljka -AU - Vujisić-Tesić B -FAU - Ostajić, Miodrag U -AU - Ostajić MU -LA - srp -PT - English Abstract -PT - Journal Article -PT - Review -PL - Serbia -TA - Srp Arh Celok Lek -JT - Srpski arhiv za celokupno lekarstvo -JID - 0027440 -SB - IM -MH - *Cardiomyopathies/diagnosis/physiopathology/therapy -MH - *Diabetes Complications/diagnosis/physiopathology/therapy -MH - Humans -RF - 50 -EDAT- 2007/12/20 09:00 -MHDA- 2008/02/06 09:00 -CRDT- 2007/12/20 09:00 -PHST- 2007/12/20 09:00 [pubmed] -PHST- 2008/02/06 09:00 [medline] -PHST- 2007/12/20 09:00 [entrez] -PST - ppublish -SO - Srp Arh Celok Lek. 2007 Sep-Oct;135(9-10):576-82. - -PMID- 19779340 -OWN - NLM -STAT- MEDLINE -DCOM- 20100406 -LR - 20100114 -IS - 1473-656X (Electronic) -IS - 1040-872X (Linking) -VI - 21 -IP - 6 -DP - 2009 Dec -TI - Cardiac disease in pregnancy. -PG - 508-13 -LID - 10.1097/GCO.0b013e328332a762 [doi] -AB - PURPOSE OF REVIEW: The past 15 years have seen a five-fold increase in the - incidence of acquired heart disease as a cause of maternal mortality in the UK, - and advances in the surgical correction of congenital heart disease have enabled - many more women to survive childhood and present at the antenatal clinic. This - review updates the reader on these important conditions. RECENT FINDINGS: The - major increased incidence of acute myocardial infarction during pregnancy has - been attributed to an increasing proportion of older women having babies (risk - 30-fold greater for women over 40 years compared with women under 20 years of - age). The obesity epidemic is associated with increases in diabetes and - hypertension. Percutaneous coronary intervention with stenting is the treatment - of choice. Although aortopathies, cardiomyopathy and valvular heart disease - present continuing problems, improvements in the management of pulmonary vascular - disease (in particular, the use of sildenafil) have reduced mortality from this - condition. Prophylaxis against endocarditis has been abandoned except for the - highest risk cases. SUMMARY: Cardiac disease in pregnancy is of growing - importance both in terms of numbers of women affected and mortality. Improvements - in care have occurred particularly in relation to ischaemic heart disease and - pulmonary hypotension. -FAU - Curry, Ruth -AU - Curry R -AD - Academic Department of Obstetrics and Gynaecology, Imperial College London, - Chelsea and Westminster Hospital, London SW10 9NH, UK. -FAU - Swan, Lorna -AU - Swan L -FAU - Steer, Philip J -AU - Steer PJ -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Curr Opin Obstet Gynecol -JT - Current opinion in obstetrics & gynecology -JID - 9007264 -SB - IM -MH - Blood Volume/physiology -MH - Cardiac Output/physiology -MH - Cardiovascular Diseases/*complications/epidemiology/*therapy -MH - Female -MH - Fetal Death/etiology -MH - Fetal Diseases/etiology -MH - Humans -MH - Maternal Age -MH - Pregnancy/physiology -MH - Pregnancy Complications, Cardiovascular/epidemiology/*therapy -MH - Premature Birth/etiology -RF - 49 -EDAT- 2009/09/26 06:00 -MHDA- 2010/04/07 06:00 -CRDT- 2009/09/26 06:00 -PHST- 2009/09/26 06:00 [entrez] -PHST- 2009/09/26 06:00 [pubmed] -PHST- 2010/04/07 06:00 [medline] -AID - 10.1097/GCO.0b013e328332a762 [doi] -PST - ppublish -SO - Curr Opin Obstet Gynecol. 2009 Dec;21(6):508-13. doi: - 10.1097/GCO.0b013e328332a762. - -PMID- 19196732 -OWN - NLM -STAT- MEDLINE -DCOM- 20090813 -LR - 20181201 -IS - 1468-201X (Electronic) -IS - 1355-6037 (Linking) -VI - 95 -IP - 15 -DP - 2009 Aug -TI - Emergence of the concept of platelet reactivity monitoring of response to - thienopyridines. -PG - 1214-9 -LID - 10.1136/hrt.2008.152660 [doi] -AB - Clinical trials have demonstrated the beneficial impact of clopidogrel in - preventing major adverse cardiovascular events (MACE), particularly in patients - undergoing percutaneous coronary intervention (PCI). The concept of biological - clopidogrel resistance emerged with the finding of persistent platelet activation - despite clopidogrel therapy in some patients. Further, a link between biological - clopidogrel resistance and thrombotic recurrence after PCI was observed and a - threshold of platelet reactivity (PR) for thrombotic events was suggested. - Consistently, in recent trials, enhanced PR inhibition translated into a - reduction in the rate of MACE after PCI. This review aims to present the - emergence of the concept of PR monitoring in patients undergoing PCI following - recent advances in this field. -FAU - Bonello, L -AU - Bonello L -AD - Washington Hospital Center, 110 Irving Street, NW, Suite 4B-1, Washington, DC - 20010, USA. -FAU - De Labriolle, A -AU - De Labriolle A -FAU - Scheinowitz, M -AU - Scheinowitz M -FAU - Lemesle, G -AU - Lemesle G -FAU - Roy, P -AU - Roy P -FAU - Steinberg, D H -AU - Steinberg DH -FAU - Pinto Slottow, T L -AU - Pinto Slottow TL -FAU - Pakala, R -AU - Pakala R -FAU - Pichard, A D -AU - Pichard AD -FAU - Barragan, P -AU - Barragan P -FAU - Camoin-Jau, L -AU - Camoin-Jau L -FAU - Dignat-George, F -AU - Dignat-George F -FAU - Paganelli, F -AU - Paganelli F -FAU - Waksman, R -AU - Waksman R -LA - eng -PT - Journal Article -PT - Review -DEP - 20090205 -PL - England -TA - Heart -JT - Heart (British Cardiac Society) -JID - 9602087 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Purinergic P2 Receptor Antagonists) -RN - 0 (Pyridines) -RN - 0 (thienopyridine) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Angioplasty, Balloon, Coronary -MH - Clopidogrel -MH - Coronary Thrombosis/*therapy -MH - Drug Resistance -MH - Humans -MH - Platelet Aggregation/*drug effects -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Platelet Function Tests -MH - Purinergic P2 Receptor Antagonists -MH - Pyridines/*therapeutic use -MH - Ticlopidine/*analogs & derivatives/therapeutic use -RF - 33 -EDAT- 2009/02/07 09:00 -MHDA- 2009/08/14 09:00 -CRDT- 2009/02/07 09:00 -PHST- 2009/02/07 09:00 [entrez] -PHST- 2009/02/07 09:00 [pubmed] -PHST- 2009/08/14 09:00 [medline] -AID - hrt.2008.152660 [pii] -AID - 10.1136/hrt.2008.152660 [doi] -PST - ppublish -SO - Heart. 2009 Aug;95(15):1214-9. doi: 10.1136/hrt.2008.152660. Epub 2009 Feb 5. - -PMID- 16251229 -OWN - NLM -STAT- MEDLINE -DCOM- 20060609 -LR - 20250623 -IS - 1468-201X (Electronic) -IS - 1355-6037 (Print) -IS - 1355-6037 (Linking) -VI - 92 -IP - 5 -DP - 2006 May -TI - Efficacy of drug eluting stents in patients with and without diabetes mellitus: - indirect comparison of controlled trials. -PG - 650-7 -AB - OBJECTIVE: To examine whether polymer based coronary stents eluting sirolimus or - paclitaxel are equally effective in patients with and without diabetes. METHODS: - Systematic review and meta-analysis by indirect comparison of randomised - controlled trials comparing stents eluting sirolimus or paclitaxel with - conventional bare metal stents. The overall study population and patients with - and without diabetes were analysed separately by using the ratio of incidence - rate ratios (RIRR). RESULTS: The analysis was based on 10 trials (six with - sirolimus, four with paclitaxel), 4513 patients (1146 patients with diabetes), - 5755 years of follow up, and 2464 events. In patients without diabetes sirolimus - eluting stents were superior to paclitaxel eluting stents with respect to - in-stent (RIRR 0.21, 95% confidence interval (CI) 0.10 to 0.48, p < 0.001) and - in-segment restenosis (RIRR 0.47, 95% CI 0.24 to 0.92, p = 0.027), target lesion - revascularisation (RIRR 0.54, 95% CI 0.30 to 0.99, p = 0.045), and major adverse - cardiac events (RIRR 0.46, 95% CI 0.26 to 0.83, p = 0.010). In patients with - diabetes the two drug eluting stents did not differ significantly in any of these - end points. Meta-regression analysis showed a significant difference between - patients with and without diabetes (tests for interaction for in-stent and - in-segment restenosis, p = 0.036 and p = 0.016). CONCLUSION: Indirect evidence - indicates that sirolimus eluting stents are superior to paclitaxel eluting stents - in patients without diabetes but not in patients with diabetes. -FAU - Stettler, C -AU - Stettler C -AD - Department of Social and Preventive Medicine, University of Bern, Bern, - Switzerland. -FAU - Allemann, S -AU - Allemann S -FAU - Egger, M -AU - Egger M -FAU - Windecker, S -AU - Windecker S -FAU - Meier, B -AU - Meier B -FAU - Diem, P -AU - Diem P -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20051026 -PL - England -TA - Heart -JT - Heart (British Cardiac Society) -JID - 9602087 -RN - 0 (Drug Implants) -RN - 0 (Immunosuppressive Agents) -RN - P88XT4IS4D (Paclitaxel) -RN - W36ZG6FT64 (Sirolimus) -SB - IM -CIN - Heart. 2006 May;92(5):579-81. doi: 10.1136/hrt.2005.082172. PMID: 16449508 -CIN - Nat Clin Pract Cardiovasc Med. 2006 Sep;3(9):480-1. doi: 10.1038/ncpcardio0634. - PMID: 16932764 -MH - Blood Vessel Prosthesis/standards -MH - Coronary Restenosis/*prevention & control -MH - Diabetic Angiopathies/*prevention & control -MH - Drug Implants -MH - Humans -MH - Immunosuppressive Agents -MH - Paclitaxel/*administration & dosage -MH - Randomized Controlled Trials as Topic -MH - Sirolimus/*administration & dosage -MH - Stents/*standards -PMC - PMC1860952 -COIS- Competing interests: none declared. -EDAT- 2005/10/28 09:00 -MHDA- 2006/06/10 09:00 -PMCR- 2009/05/01 -CRDT- 2005/10/28 09:00 -PHST- 2005/10/28 09:00 [pubmed] -PHST- 2006/06/10 09:00 [medline] -PHST- 2005/10/28 09:00 [entrez] -PHST- 2009/05/01 00:00 [pmc-release] -AID - hrt.2005.070698 [pii] -AID - ht70698 [pii] -AID - 10.1136/hrt.2005.070698 [doi] -PST - ppublish -SO - Heart. 2006 May;92(5):650-7. doi: 10.1136/hrt.2005.070698. Epub 2005 Oct 26. - -PMID- 19389061 -OWN - NLM -STAT- MEDLINE -DCOM- 20090826 -LR - 20090514 -IS - 1467-789X (Electronic) -IS - 1467-7881 (Linking) -VI - 10 -IP - 3 -DP - 2009 May -TI - Adiponectin: from obesity to cardiovascular disease. -PG - 269-79 -LID - 10.1111/j.1467-789X.2009.00571.x [doi] -AB - Adiponectin is an adipokine whose biosynthesis is deranged in obesity and - diabetes mellitus, predisposing to atherosclerosis. Evidence suggests that - adiponectin has anti-atherogenic properties by improving endothelial function and - having anti-inflammatory effects in the vascular wall. In addition, adiponectin - modifies vascular intracellular redox signalling and exerts indirect antioxidant - effects on human myocardium. However, its clinical role in cardiovascular disease - is obscure. Adiponectin's positive prognostic value in coronary artery disease - had been widely supported over the last years, but this view has been questioned - recently. High adiponectin levels are paradoxically associated with poorer - prognosis in heart failure syndrome. These controversial findings seem surprising - as adiponectin has been viewed overall as an anti-atherogenic molecule. - Therefore, any certain conclusion about adiponectin's role in cardiovascular - disease seems premature. Despite the rapidly accumulating literature on this - adipokine, it is still unclear whether adiponectin is a key mediator or a - bystander in cardiovascular disease. It is still uncertain whether adiponectin - levels have any clinical significance for risk stratification in cardiovascular - disease or they just reflect the activation of complex and opposing underlying - mechanisms. Circulating adiponectin levels should be interpreted with caution, as - they may have completely different prognostic value, depending on the underlying - disease state. -FAU - Antoniades, C -AU - Antoniades C -AD - 1st Cardiology Department, Athens University Medical School, Athens, Greece. - antoniades@panafonet.gr -FAU - Antonopoulos, A S -AU - Antonopoulos AS -FAU - Tousoulis, D -AU - Tousoulis D -FAU - Stefanadis, C -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -DEP - 20090306 -PL - England -TA - Obes Rev -JT - Obesity reviews : an official journal of the International Association for the - Study of Obesity -JID - 100897395 -RN - 0 (Adiponectin) -SB - IM -MH - Adiponectin/*biosynthesis -MH - Cardiovascular Diseases/*metabolism/therapy -MH - Humans -MH - Obesity/metabolism -RF - 82 -EDAT- 2009/04/25 09:00 -MHDA- 2009/08/27 09:00 -CRDT- 2009/04/25 09:00 -PHST- 2009/04/25 09:00 [entrez] -PHST- 2009/04/25 09:00 [pubmed] -PHST- 2009/08/27 09:00 [medline] -AID - OBR571 [pii] -AID - 10.1111/j.1467-789X.2009.00571.x [doi] -PST - ppublish -SO - Obes Rev. 2009 May;10(3):269-79. doi: 10.1111/j.1467-789X.2009.00571.x. Epub 2009 - Mar 6. - -PMID- 23470080 -OWN - NLM -STAT- MEDLINE -DCOM- 20130920 -LR - 20190907 -IS - 1873-4294 (Electronic) -IS - 1568-0266 (Linking) -VI - 13 -IP - 2 -DP - 2013 -TI - Copeptin as a biomarker in cardiac disease. -PG - 231-40 -AB - The introduction of biochemical biomarkers in the evaluation of patients with - cardiovascular disease has led to practice-changing advancements in the way these - patients are diagnosed and managed. Measurements of cardiac troponins or - brain-type natriuretic peptide (BNP) and its precursor, N-terminal brain-type - natriuretic peptide (NT-proBNP), have become indispensable in the evaluation of - patients with acute coronary syndromes and heart failure, respectively, - constituting an integral part of the diagnostic algorithm and risk stratification - of these conditions. Copeptin, a glycopeptide, part of the prehormone molecule of - the antidiuretic hormone - or arginine-vasopressin - has shown considerable - promise in this field. There is evidence that copeptin might be useful as a - diagnostic or prognostic biomarker and risk-stratifier in a range of - cardiovascular disease conditions. The main clinical scenarios where copeptin has - been studied as a biomarker are: early rule-out of myocardial infarction in - patients with acute chest pain, diagnosis of heart failure in patients with acute - dyspnea and determining the prognosis of destabilized or chronic stable heart - failure. The present review is aimed at providing concise information about the - molecular structure and biosynthesis of copeptin, the available medical chemistry - methods of quantification, and the potential clinical uses of this molecule in - patients with heart disease. -FAU - Giannopoulos, Georgios -AU - Giannopoulos G -AD - Department of Cardiology, Athens General Hospital G. Gennimatas, Athens, Greece. - ggiann@med.uoa.gr -FAU - Deftereos, Spyridon -AU - Deftereos S -FAU - Panagopoulou, Vasiliki -AU - Panagopoulou V -FAU - Kossyvakis, Charalambos -AU - Kossyvakis C -FAU - Kaoukis, Andreas -AU - Kaoukis A -FAU - Bouras, Georgios -AU - Bouras G -FAU - Pyrgakis, Vlassios -AU - Pyrgakis V -FAU - Cleman, Michael W -AU - Cleman MW -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Top Med Chem -JT - Current topics in medicinal chemistry -JID - 101119673 -RN - 0 (Biomarkers) -RN - 0 (Glycopeptides) -RN - 0 (copeptins) -SB - IM -MH - Amino Acid Sequence -MH - Biomarkers/*blood -MH - Cardiovascular Diseases/diagnosis/*metabolism -MH - Glycopeptides/*blood/chemistry/metabolism -MH - Heart Failure/diagnosis/metabolism -MH - Humans -MH - Molecular Sequence Data -MH - Myocardial Infarction/diagnosis/metabolism -MH - Predictive Value of Tests -EDAT- 2013/03/09 06:00 -MHDA- 2013/09/21 06:00 -CRDT- 2013/03/09 06:00 -PHST- 2012/11/27 00:00 [received] -PHST- 2012/12/20 00:00 [revised] -PHST- 2013/01/10 00:00 [accepted] -PHST- 2013/03/09 06:00 [entrez] -PHST- 2013/03/09 06:00 [pubmed] -PHST- 2013/09/21 06:00 [medline] -AID - CTMC-EPUB-20130304-10 [pii] -AID - 10.2174/15680266113139990088 [doi] -PST - ppublish -SO - Curr Top Med Chem. 2013;13(2):231-40. doi: 10.2174/15680266113139990088. - -PMID- 24066200 -OWN - NLM -STAT- MEDLINE -DCOM- 20140513 -LR - 20211021 -IS - 1947-6108 (Electronic) -IS - 1947-6094 (Print) -IS - 1947-6108 (Linking) -VI - 9 -IP - 3 -DP - 2013 Jul-Sep -TI - Cardiac MR for the assessment of myocardial viability. -PG - 163-8 -AB - This article focuses on delayed contrast enhanced MRI (DE-MRI) to assess - myocardial viability. We start by discussing previous literature that evaluated - the potential importance of myocardial viability testing and follow up with the - more recent Surgical Treatment for Heart Disease Trial (STICH) trial results. We - then provide an overview of the basic concepts and technical aspects of the - current DE-MRI technique and review the initial studies demonstrating that DE-MRI - before coronary revascularization can predict functional improvement. Finally, we - use DE-MRI as a paradigm to discuss physiological insights into viability - assessment and examine common assumptions in the metrics used to evaluate - viability techniques. -FAU - Van Assche, Lowie M R -AU - Van Assche LM -AD - Duke University Medical Center, Durham, North Carolina. -FAU - Kim, Han W -AU - Kim HW -FAU - Kim, Raymond J -AU - Kim RJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Methodist Debakey Cardiovasc J -JT - Methodist DeBakey cardiovascular journal -JID - 101508600 -SB - IM -MH - Heart Ventricles/*pathology/physiopathology -MH - Humans -MH - Magnetic Resonance Imaging, Cine/*methods -MH - Myocardial Ischemia/*diagnosis/physiopathology -MH - Myocardium/*pathology -MH - Ventricular Function/*physiology -PMC - PMC3782324 -OTO - NOTNLM -OT - cardiac magnetic resonance -OT - hibernation -OT - ischemic heart disease -OT - left ventricular dysfunction -OT - myocardial viability -OT - stunning -COIS- Conflict of Interest Disclosure: The authors have completed and submitted the - Methodist DeBakey Cardiovascular Journal Conflict of Interest Statement and the - following was reported: Dr. Raymond Kim is a cofounder of Heart IT. -EDAT- 2013/09/26 06:00 -MHDA- 2014/05/14 06:00 -PMCR- 2013/07/01 -CRDT- 2013/09/26 06:00 -PHST- 2013/09/26 06:00 [entrez] -PHST- 2013/09/26 06:00 [pubmed] -PHST- 2014/05/14 06:00 [medline] -PHST- 2013/07/01 00:00 [pmc-release] -AID - MDCVJ_0903n [pii] -AID - 10.14797/mdcj-9-3-163 [doi] -PST - ppublish -SO - Methodist Debakey Cardiovasc J. 2013 Jul-Sep;9(3):163-8. doi: - 10.14797/mdcj-9-3-163. - -PMID- 18344027 -OWN - NLM -STAT- MEDLINE -DCOM- 20080715 -LR - 20220409 -IS - 0340-9937 (Print) -IS - 0340-9937 (Linking) -VI - 33 -IP - 2 -DP - 2008 Mar -TI - Pathophysiology of myocardial infarction: protection by ischemic pre- and - postconditioning. -PG - 88-100 -LID - 10.1007/s00059-008-3101-9 [doi] -AB - One or several short cycles of ischemia/reperfusion before (preconditioning) or - after (postconditioning) a sustained coronary occlusion with subsequent - reperfusion reduce the ultimate infarct size. The protection is potent, but - limited to a narrow time frame. In animal experiments, a complex signal - transduction cascade was identified which results specifically in a reduction of - reperfusion injury. There is evidence for both ischemic pre- and postconditioning - in patients with coronary artery disease. -FAU - Skyschally, Andreas -AU - Skyschally A -AD - Institute of Pathophysiology,West German Heart Center, UniversityHospital Essen, - Germany. -FAU - Schulz, Rainer -AU - Schulz R -FAU - Heusch, Gerd -AU - Heusch G -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -SB - IM -MH - Animals -MH - Apoptosis/physiology -MH - Humans -MH - *Ischemic Preconditioning, Myocardial -MH - Myocardial Infarction/pathology/*physiopathology/therapy -MH - Myocardial Reperfusion Injury/pathology/*physiopathology/prevention & control -MH - Myocardium/pathology -MH - Signal Transduction/physiology -RF - 184 -EDAT- 2008/03/18 09:00 -MHDA- 2008/07/17 09:00 -CRDT- 2008/03/18 09:00 -PHST- 2008/03/18 09:00 [pubmed] -PHST- 2008/07/17 09:00 [medline] -PHST- 2008/03/18 09:00 [entrez] -AID - 10.1007/s00059-008-3101-9 [doi] -PST - ppublish -SO - Herz. 2008 Mar;33(2):88-100. doi: 10.1007/s00059-008-3101-9. - -PMID- 22520295 -OWN - NLM -STAT- MEDLINE -DCOM- 20130213 -LR - 20120827 -IS - 1532-8430 (Electronic) -IS - 0022-0736 (Linking) -VI - 45 -IP - 5 -DP - 2012 Sep -TI - Sleep apnea, cardiac arrhythmias, and conduction disorders. -PG - 508-12 -LID - 10.1016/j.jelectrocard.2012.03.003 [doi] -AB - Sleep apnea (SA) is a common breathing disorder. It is associated with a myriad - of medical conditions including increased cardiovascular morbidity and mortality. - Recent studies have shown that cardiac arrhythmias and conduction disorders are - common in patients with SA. Sleep apnea has also been also linked to heart - failure, hypertension, coronary artery disease, and stroke. The purpose of this - brief review is to analyze the available information that links SA with different - cardiac arrhythmias and conduction disorders and the role of intracardiac devices - for the diagnosis and management of this condition. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Baranchuk, Adrian -AU - Baranchuk A -AD - Cardiology Division, Kingston General Hospital, Queen's University, Kingston, - Ontario, Canada. barancha@kgh.kari.net -LA - eng -PT - Journal Article -PT - Review -DEP - 20120420 -PL - United States -TA - J Electrocardiol -JT - Journal of electrocardiology -JID - 0153605 -SB - IM -CIN - J Electrocardiol. 2012 Sep;45(5):513-4. doi: 10.1016/j.jelectrocard.2012.06.013. - PMID: 22920787 -MH - Arrhythmias, Cardiac/*etiology/*physiopathology -MH - Electrocardiography/*methods -MH - Heart Conduction System/*physiopathology -MH - Humans -MH - Sleep Apnea Syndromes/*complications/*physiopathology -MH - Stroke/*etiology/*physiopathology -EDAT- 2012/04/24 06:00 -MHDA- 2013/02/14 06:00 -CRDT- 2012/04/24 06:00 -PHST- 2012/02/08 00:00 [received] -PHST- 2012/04/24 06:00 [entrez] -PHST- 2012/04/24 06:00 [pubmed] -PHST- 2013/02/14 06:00 [medline] -AID - S0022-0736(12)00103-3 [pii] -AID - 10.1016/j.jelectrocard.2012.03.003 [doi] -PST - ppublish -SO - J Electrocardiol. 2012 Sep;45(5):508-12. doi: 10.1016/j.jelectrocard.2012.03.003. - Epub 2012 Apr 20. - -PMID- 19331794 -OWN - NLM -STAT- MEDLINE -DCOM- 20090505 -LR - 20090331 -IS - 1646-0758 (Electronic) -IS - 0870-399X (Linking) -VI - 21 -IP - 6 -DP - 2008 Nov-Dec -TI - [Impact of psychosocial factors on heart valve surgery]. -PG - 601-6 -AB - Despite the raising number of cardiac valve surgeries performed each year, it is - evident the lack of studies concerning the psychosocial aspects and their impact - on prognostic in these patients. This connection is well established on - cardiovascular disease and on patients submitted to cardiac surgery of ischemic - states, like coronary artery bypass surgery; in these cases recent studies - revealed that the presence of depressive and/or anxious symptoms worsened the - prognostic with significant impact on the quality of life. The aim of the present - literature review it is to take knowledge of the psychosocial factors on patients - submitted to valve surgery and the possible pathophysiological hypotheses that - may clarify that connection. The identification of non surgical predictive - factors, of psychosocial nature, might allow an early approach with a prognostic - improvement. -FAU - Costa, Cassilda -AU - Costa C -AD - Serviço Psiquiatria. Hospital de São João, Porto. -FAU - Teixeira-Sousa, Vera -AU - Teixeira-Sousa V -FAU - Costa, Adelaide -AU - Costa A -FAU - Reis, Constança -AU - Reis C -FAU - Grangeia, Rosa -AU - Grangeia R -FAU - Coelho, Rui -AU - Coelho R -LA - por -PT - English Abstract -PT - Journal Article -PT - Review -TT - Impacto dos factores psicossociais na cirurgia valvular cardíaca. -DEP - 20090324 -PL - Portugal -TA - Acta Med Port -JT - Acta medica portuguesa -JID - 7906803 -SB - IM -MH - Cardiac Surgical Procedures/*psychology -MH - Heart Valves/*surgery -MH - Humans -RF - 26 -EDAT- 2009/04/01 09:00 -MHDA- 2009/05/06 09:00 -CRDT- 2009/04/01 09:00 -PHST- 2007/10/08 00:00 [received] -PHST- 2008/01/06 00:00 [accepted] -PHST- 2009/04/01 09:00 [entrez] -PHST- 2009/04/01 09:00 [pubmed] -PHST- 2009/05/06 09:00 [medline] -PST - ppublish -SO - Acta Med Port. 2008 Nov-Dec;21(6):601-6. Epub 2009 Mar 24. - -PMID- 19948095 -OWN - NLM -STAT- MEDLINE -DCOM- 20100304 -LR - 20211020 -IS - 1546-9549 (Electronic) -IS - 1546-9530 (Linking) -VI - 6 -IP - 4 -DP - 2009 Dec -TI - Stress cardiomyopathy syndrome: a contemporary review. -PG - 265-71 -AB - Stress cardiomyopathy (SC) syndrome represents a reversible form of - cardiomyopathy that commonly presents proximate to an acute emotional or - physiologic stressor. The clinical presentation is similar to an acute coronary - syndrome in the absence of obstructive coronary artery disease to explain the - unusual distribution of associated transient wall motion abnormalities. - Postmenopausal women seem particularly prone to SC for unclear reasons. The - pathophysiology of the syndrome is unknown but may involve pathologic sympathetic - myocardial stimulation. -FAU - Kapoor, Divya -AU - Kapoor D -AD - University of Missouri-Kansas City, 12330 Metcalf Avenue, Suite 280, Overland - Park, KS 66213, USA. kbybee@cc-pc.com -FAU - Bybee, Kevin A -AU - Bybee KA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Heart Fail Rep -JT - Current heart failure reports -JID - 101196487 -SB - IM -MH - Cardiac Catheterization -MH - Diagnosis, Differential -MH - Echocardiography -MH - Electrocardiography -MH - Humans -MH - Magnetic Resonance Imaging -MH - Prognosis -MH - Stress, Psychological/*complications -MH - Syndrome -MH - *Takotsubo Cardiomyopathy/diagnosis/etiology/physiopathology -MH - Tomography, Emission-Computed, Single-Photon -MH - Ventricular Function, Right/*physiology -RF - 45 -EDAT- 2009/12/02 06:00 -MHDA- 2010/03/05 06:00 -CRDT- 2009/12/02 06:00 -PHST- 2009/12/02 06:00 [entrez] -PHST- 2009/12/02 06:00 [pubmed] -PHST- 2010/03/05 06:00 [medline] -AID - 10.1007/s11897-009-0036-2 [doi] -PST - ppublish -SO - Curr Heart Fail Rep. 2009 Dec;6(4):265-71. doi: 10.1007/s11897-009-0036-2. - -PMID- 19556177 -OWN - NLM -STAT- MEDLINE -DCOM- 20100107 -LR - 20220410 -IS - 1876-861X (Electronic) -IS - 1876-861X (Linking) -VI - 3 -IP - 5 -DP - 2009 Sep-Oct -TI - Noncardiac findings on cardiac CT part I: Pros and cons. -PG - 293-9 -LID - 10.1016/j.jcct.2009.05.003 [doi] -AB - Cardiac computed tomography (CT) has evolved into an effective imaging technique - for the evaluation of coronary artery disease in selected patients. Two distinct - advantages over other noninvasive imaging modalities include its ability to - evaluate directly the coronary arteries and to provide an opportunity to evaluate - extracardiac structures, such as the lungs and mediastinum. Some centers - reconstruct a small field of view (FOV) cropped around the heart, but a full FOV - (from skin to skin in the irradiated area) is obtainable in the raw data of every - scan so that clinically relevant noncardiac findings are identifiable. Debate in - the scientific community has centered on the necessity for this large FOV - evaluation. A review of noncardiac structures provides the opportunity to make - alternative diagnoses that may account for the patient's presentation or to - detect important but clinically silent problems such as lung cancer. Critics - argue that the yield of biopsy-proven cancers is low and that the follow-up of - incidental noncardiac findings is expensive, resulting in increased radiation - exposure and possibly unnecessary further testing. In this two-part review we - outline the issues surrounding the concept of the noncardiac read looking for - noncardiac findings on cardiac CT. Part I focuses on the pros and cons of the - practice of identifying noncardiac findings on cardiac CT. -FAU - Killeen, Ronan P -AU - Killeen RP -AD - Department of Radiology, St. Vincent's University Hospital, Dublin 4, Ireland. -FAU - Dodd, Jonathan D -AU - Dodd JD -FAU - Cury, Ricardo C -AU - Cury RC -LA - eng -PT - Journal Article -PT - Review -DEP - 20090513 -PL - United States -TA - J Cardiovasc Comput Tomogr -JT - Journal of cardiovascular computed tomography -JID - 101308347 -SB - IM -MH - Heart Diseases/*diagnostic imaging -MH - Humans -MH - *Incidental Findings -MH - Lung Diseases/*diagnostic imaging -MH - Radiography, Abdominal/*methods/*trends -MH - Tomography, X-Ray Computed/*methods/*trends -RF - 33 -EDAT- 2009/06/27 09:00 -MHDA- 2010/01/08 06:00 -CRDT- 2009/06/27 09:00 -PHST- 2009/01/28 00:00 [received] -PHST- 2009/05/02 00:00 [revised] -PHST- 2009/05/05 00:00 [accepted] -PHST- 2009/06/27 09:00 [entrez] -PHST- 2009/06/27 09:00 [pubmed] -PHST- 2010/01/08 06:00 [medline] -AID - S1934-5925(09)00156-7 [pii] -AID - 10.1016/j.jcct.2009.05.003 [doi] -PST - ppublish -SO - J Cardiovasc Comput Tomogr. 2009 Sep-Oct;3(5):293-9. doi: - 10.1016/j.jcct.2009.05.003. Epub 2009 May 13. - -PMID- 23263572 -OWN - NLM -STAT- MEDLINE -DCOM- 20130408 -LR - 20220409 -IS - 1530-0293 (Electronic) -IS - 0090-3493 (Linking) -VI - 41 -IP - 2 -DP - 2013 Feb -TI - Role of the venous return in critical illness and shock: part II-shock and - mechanical ventilation. -PG - 573-9 -LID - 10.1097/CCM.0b013e31827bfc25 [doi] -AB - OBJECTIVE: To provide a conceptual and clinical review of the physiology of the - venous system as it is related to cardiac function in health and disease. DATA: - An integration of venous and cardiac physiology under normal conditions, critical - illness, and resuscitation. SUMMARY: The usual clinical teaching of cardiac - physiology focuses on left ventricular pathophysiology and pathology. Due to the - wide array of shock states dealt with by intensivists, an integrated approach - that takes into account the function of the venous system and its interaction - with the right heart may be more useful. In part II of this two-part review, we - describe the physiology of venous return and its interaction with the right heart - function as it relates to mechanical ventilation and various shock states - including hypovolemic, cardiogenic, obstructive, and septic shock. In particular, - we demonstrate how these shock states perturb venous return/right heart - interactions. We also show how compensatory mechanisms and therapeutic - interventions can tend to return venous return and cardiac output to appropriate - values. CONCLUSION: An improved understanding of the role of the venous system in - pathophysiologic conditions will allow intensivists to better appreciate the - complex circulatory physiology of shock and related therapies. This should enable - improved hemodynamic management of this disorder. -FAU - Funk, Duane J -AU - Funk DJ -AD - Section of Critical Care Medicine, Department of Medicine, University of - Manitoba, Manitoba, Canada. -FAU - Jacobsohn, Eric -AU - Jacobsohn E -FAU - Kumar, Anand -AU - Kumar A -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Med -JT - Critical care medicine -JID - 0355501 -RN - 0 (Cardiotonic Agents) -RN - 0 (Catecholamines) -RN - 0 (Cytokines) -RN - 0 (Vasoconstrictor Agents) -RN - 0 (Vasodilator Agents) -RN - 31C4KY9ESH (Nitric Oxide) -SB - IM -CIN - Crit Care Med. 2013 Sep;41(9):e237-9. doi: 10.1097/CCM.0b013e318291c1c4. PMID: - 23979389 -CIN - Crit Care Med. 2013 Sep;41(9):e239. doi: 10.1097/CCM.0b013e318299576a. PMID: - 23979390 -MH - Blood Pressure/physiology -MH - Cardiac Output/physiology -MH - Cardiotonic Agents/therapeutic use -MH - Catecholamines/metabolism -MH - Coronary Circulation/*physiology -MH - *Critical Illness -MH - Cytokines/metabolism -MH - Fluid Therapy -MH - Humans -MH - Hypovolemia/physiopathology/therapy -MH - Nitric Oxide/metabolism -MH - Pneumothorax/physiopathology -MH - *Positive-Pressure Respiration -MH - Shock/*physiopathology/therapy -MH - Stroke Volume/physiology -MH - Vasoconstrictor Agents/therapeutic use -MH - Vasodilator Agents/therapeutic use -MH - Ventricular Dysfunction/physiopathology/therapy -EDAT- 2012/12/25 06:00 -MHDA- 2013/04/09 06:00 -CRDT- 2012/12/25 06:00 -PHST- 2012/12/25 06:00 [entrez] -PHST- 2012/12/25 06:00 [pubmed] -PHST- 2013/04/09 06:00 [medline] -AID - 10.1097/CCM.0b013e31827bfc25 [doi] -PST - ppublish -SO - Crit Care Med. 2013 Feb;41(2):573-9. doi: 10.1097/CCM.0b013e31827bfc25. - -PMID- 27147838 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20160505 -LR - 20201001 -IS - 1179-1500 (Print) -IS - 1179-1500 (Electronic) -IS - 1179-1500 (Linking) -VI - 2 -DP - 2010 -TI - ACE inhibitors - angiotensin II receptor antagonists: A useful combination - therapy for ischemic heart disease. -PG - 51-9 -AB - Morbidity and mortality from cardiovascular diseases are still high, even with - the use of the best available therapies. There is mounting evidence that - excessive renin-angiotensin system activation triggers much of the damaging and - progressive nature of cardiovascular and kidney diseases through expression of - angiotensin II. Moreover, angiotensin II play a major role in the development of - end organ damage through a variety of inflammatory mechanisms. Today, - angiotensins-converting enzyme (ACE) inhibitors and angiotensin II receptor - antagonists have clearly demonstrated their efficacy in preventing target organ - damage and in reducing cardiovascular morbidity and mortality in ischemic heart - disease (IHD). Moreover, the development of angiotensin II receptor antagonists - has enabled a large gain in tolerability and safety. Several clinical trials have - firmly established that these drugs act on the renin-angiotensin system, reducing - the incidence of coronary events with monotherapy and combination therapy. In - this review we summarize the role mono- and combined therapy of ACE inhibitors - and angiotensin II receptor antagonists play in ischemic heart disease. In this - respect the review will improve ideas for developing new formulations with - combinations of these drugs in the future. -FAU - Saleem, T S Mohamed -AU - Saleem TS -AD - Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet-516126, - Kadapa Dist, Andhra Pradesh, India. -FAU - Bharani, K -AU - Bharani K -AD - Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet-516126, - Kadapa Dist, Andhra Pradesh, India. -FAU - Gauthaman, K -AU - Gauthaman K -AD - Department of Drug Technology, Higher Institute of Medical Technology, Derna, - Libya. -LA - eng -PT - Journal Article -PT - Review -DEP - 20100701 -PL - New Zealand -TA - Open Access Emerg Med -JT - Open access emergency medicine : OAEM -JID - 101570796 -PMC - PMC4806827 -OTO - NOTNLM -OT - angiotensin II -OT - angiotensin receptor blockers -OT - renin angiotensin system -EDAT- 2010/01/01 00:00 -MHDA- 2010/01/01 00:01 -PMCR- 2010/07/01 -CRDT- 2016/05/06 06:00 -PHST- 2016/05/06 06:00 [entrez] -PHST- 2010/01/01 00:00 [pubmed] -PHST- 2010/01/01 00:01 [medline] -PHST- 2010/07/01 00:00 [pmc-release] -AID - oaem-2-051 [pii] -AID - 10.2147/oaem.s10507 [doi] -PST - epublish -SO - Open Access Emerg Med. 2010 Jul 1;2:51-9. doi: 10.2147/oaem.s10507. eCollection - 2010. - -PMID- 23932258 -OWN - NLM -STAT- MEDLINE -DCOM- 20131114 -LR - 20181202 -IS - 1552-6259 (Electronic) -IS - 0003-4975 (Linking) -VI - 96 -IP - 3 -DP - 2013 Sep -TI - Association between obesity and postoperative atrial fibrillation in patients - undergoing cardiac operations: a systematic review and meta-analysis. -PG - 1104-16 -LID - S0003-4975(13)00840-0 [pii] -LID - 10.1016/j.athoracsur.2013.04.029 [doi] -AB - In a systematic review and random-effects meta-analysis, we evaluated whether - obesity is associated with postoperative atrial fibrillation (POAF) in patients - undergoing cardiac operations. We selected 18 observational studies until - December 2011 that excluded patients with preoperative AF (n=36,147). Obese - patients had a modest higher risk of POAF compared with nonobese (odds ratio, - 1.12; 95% confidence interval, 1.04 to 1.21; p=0.002). The association between - obesity and POAF did not vary substantially by type of cardiac operation, study - design, or year of publication. POAF was significantly associated with a higher - risk of stroke, respiratory failure, and operative death. -CI - Copyright © 2013 The Society of Thoracic Surgeons. Published by Elsevier Inc. All - rights reserved. -FAU - Hernandez, Adrian V -AU - Hernandez AV -AD - Postgraduate School, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru. - adrianhernandezdiaz@gmail.com -FAU - Kaw, Roop -AU - Kaw R -FAU - Pasupuleti, Vinay -AU - Pasupuleti V -FAU - Bina, Pouya -AU - Bina P -FAU - Ioannidis, John P A -AU - Ioannidis JP -FAU - Bueno, Hector -AU - Bueno H -FAU - Boersma, Eric -AU - Boersma E -FAU - Gillinov, Marc -AU - Gillinov M -CN - Cardiovascular Meta-Analyses Research Group -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Meta-Analysis -PT - Review -PT - Systematic Review -DEP - 20130809 -PL - Netherlands -TA - Ann Thorac Surg -JT - The Annals of thoracic surgery -JID - 15030100R -SB - IM -MH - Atrial Fibrillation/*epidemiology/etiology/physiopathology -MH - Body Mass Index -MH - Cardiac Surgical Procedures/*adverse effects/methods -MH - Cause of Death -MH - Female -MH - Hospital Mortality/*trends -MH - Humans -MH - Incidence -MH - Male -MH - Obesity/*complications/diagnosis/surgery -MH - Postoperative Complications/epidemiology/etiology -MH - Prognosis -MH - Reference Values -MH - Risk Assessment -MH - Survival Analysis -OTO - NOTNLM -OT - 24 -OT - ACE -OT - AF -OT - ARBs -OT - BMI -OT - BSA -OT - CABG -OT - CAD -OT - CHF -OT - CI -OT - CK-MB -OT - COPD -OT - CPBT -OT - CVD -OT - DM -OT - ECC -OT - EDIVST -OT - EF -OT - ESIVST -OT - FE -OT - FFP -OT - HDL -OT - IABP -OT - ICU -OT - IV -OT - LDL -OT - LVEF -OT - M-H -OT - MI -OT - MOOSE -OT - Mantel-Haenszel -OT - Meta-analysis of Observational Studies in Epidemiology -OT - NA -OT - OR -OT - PC -OT - POAF -OT - PRISMA -OT - PUFA -OT - PVD -OT - Preferred Reporting Items for Systematic Reviews and Meta-Analyses -OT - RBC -OT - RC -OT - RF -OT - SD -OT - SE -OT - SPB -OT - angiotensin II receptor blockers -OT - angiotensin-converting enzyme -OT - atrial fibrillation -OT - body mass index -OT - body surface area -OT - cardiopulmonary bypass time -OT - cerebrovascular disease -OT - chronic obstructive pulmonary disease -OT - confidence interval -OT - congestive heart failure -OT - coronary artery bypass grafting -OT - coronary artery disease -OT - creatinine kinase-myocardial band -OT - diabetes mellitus -OT - ejection fraction -OT - end-diastolic intraventricular septum thickness -OT - end-systolic intraventricular septum thickness -OT - extracorporeal circulation -OT - finite element -OT - fresh frozen plasma -OT - high density lipoprotein -OT - intensive care unit -OT - intraaortic balloon pump -OT - inverse variance -OT - left ventricular ejection fraction -OT - low density lipoprotein -OT - myocardial infarction -OT - not available -OT - odds ratio -OT - peripheral vascular disease -OT - polyunsaturated fatty acid -OT - postoperative atrial fibrillation -OT - prospective cohort -OT - red blood cells -OT - respiratory failure -OT - retrospective cohort -OT - standard deviation -OT - standard error -OT - supraventricular premature beats -EDAT- 2013/08/13 06:00 -MHDA- 2013/11/15 06:00 -CRDT- 2013/08/13 06:00 -PHST- 2013/01/03 00:00 [received] -PHST- 2013/03/31 00:00 [revised] -PHST- 2013/04/02 00:00 [accepted] -PHST- 2013/08/13 06:00 [entrez] -PHST- 2013/08/13 06:00 [pubmed] -PHST- 2013/11/15 06:00 [medline] -AID - S0003-4975(13)00840-0 [pii] -AID - 10.1016/j.athoracsur.2013.04.029 [doi] -PST - ppublish -SO - Ann Thorac Surg. 2013 Sep;96(3):1104-16. doi: 10.1016/j.athoracsur.2013.04.029. - Epub 2013 Aug 9. - -PMID- 21879649 -OWN - NLM -STAT- MEDLINE -DCOM- 20110927 -LR - 20191112 -IS - 0354-950X (Print) -IS - 0354-950X (Linking) -VI - 58 -IP - 2 -DP - 2011 -TI - Preoperative preparation of patients with cardiomyopathies in non-cardiac - surgery. -PG - 39-43 -AB - Cardiomyopathies are myocardial diseases in which there is structural and - functional disorder of the heart muscle, in the absence of coronary artery - disease, hypertension, valvular disease and congenital heart disease. - Cardiomyopathies are grouped into specific morphological and functional - phenotypes: dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive - cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy and unclassified - cardiomyopathies. Patients with dilated and hypertrophic cardiomypathy are prone - to the development of congestive heart failure in the perioperative period. Also, - patients with hypertrophic and arrhythmogenic right ventricular cardiomyopathy - are prone to arrhythmias in the perioperative period. Preoperative evaluation - includes history, physical examination, ECG, chest radiography, complete blood - count, electrolytes, creatinine, glomerular filtration rate, glucose, liver - enzymes, urin analysis, BNP and echocardiographic evaluation of left ventricular - function. Drug therapy should be optimized and continued preoperatively. Surgery - should be delayed (unless urgent) in patients with decompensated or untreated - cardiomyopathy. Preoperative evaluation requires integrated multidisciplinary - approach of anesthesiologists, cardiologist and surgeons. -FAU - Bradić, Zeljko -AU - Bradić Z -AD - Center for Anesthesiology, Clinical Center of Serbia, Belgrade, Serbia. -FAU - Ivanović, Branislava -AU - Ivanović B -FAU - Marković, Dejan -AU - Marković D -FAU - Simić, Dusica -AU - Simić D -FAU - Janković, Radmilo -AU - Janković R -FAU - Kalezić, Nevena -AU - Kalezić N -LA - eng -PT - Journal Article -PT - Review -PL - Serbia -TA - Acta Chir Iugosl -JT - Acta chirurgica Iugoslavica -JID - 0372631 -SB - IM -MH - Arrhythmogenic Right Ventricular Dysplasia/therapy -MH - Cardiomyopathies/*diagnosis/*therapy -MH - Cardiomyopathy, Dilated/diagnosis/therapy -MH - Cardiomyopathy, Hypertrophic/diagnosis/therapy -MH - Cardiomyopathy, Restrictive/diagnosis/therapy -MH - Humans -MH - *Preoperative Care -EDAT- 2011/09/02 06:00 -MHDA- 2011/09/29 06:00 -CRDT- 2011/09/02 06:00 -PHST- 2011/09/02 06:00 [entrez] -PHST- 2011/09/02 06:00 [pubmed] -PHST- 2011/09/29 06:00 [medline] -AID - 10.2298/aci1102039b [doi] -PST - ppublish -SO - Acta Chir Iugosl. 2011;58(2):39-43. doi: 10.2298/aci1102039b. - -PMID- 22999223 -OWN - NLM -STAT- MEDLINE -DCOM- 20130226 -LR - 20121105 -IS - 0870-2551 (Print) -IS - 0870-2551 (Linking) -VI - 31 -IP - 11 -DP - 2012 Nov -TI - [Diagnosis, prevention and treatment of cardiac allograft vasculopathy]. -PG - 721-30 -LID - S0870-2551(12)00193-X [pii] -LID - 10.1016/j.repc.2012.08.001 [doi] -AB - The major limitation of long-term survival after cardiac transplantation is - allograft vasculopathy, which consists of concentric and diffuse intimal - hyperplasia. The disease still has a significant incidence, estimated at 30% five - years after cardiac transplantation. It is a clinically silent disease and so - diagnosis is a challenge. Coronary angiography supplemented by intravascular - ultrasound is the most sensitive diagnostic method. However, new non-invasive - diagnostic techniques are likely to be clinically relevant in the future. The - earliest possible diagnosis is essential to prevent progression of the disease - and to improve its prognosis. A new nomenclature for allograft vasculopathy has - been published in July 2010, developed by the International Society for Heart and - Lung Transplantation (ISHLT), establishing a standardized definition. - Simultaneously, the ISHLT published new guidelines standardizing the diagnosis - and management of cardiac transplant patients. This paper reviews contemporary - concepts in the pathophysiology, diagnosis, prevention and treatment of allograft - vasculopathy, highlighting areas that are the subject of ongoing research. -CI - Copyright © 2010 Sociedade Portuguesa de Cardiologia. Published by Elsevier - España. All rights reserved. -FAU - Calé, Rita -AU - Calé R -AD - Departamento de Cardiologia e Cirurgia Cardiotorácica, Hospital Santa Cruz, - Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal. ritacale@hotmail.com -FAU - Rebocho, Maria José -AU - Rebocho MJ -FAU - Aguiar, Carlos -AU - Aguiar C -FAU - Almeida, Manuel -AU - Almeida M -FAU - Queiroz E Melo, João -AU - Queiroz E Melo J -FAU - Silva, José Aniceto -AU - Silva JA -LA - por -PT - English Abstract -PT - Journal Article -PT - Review -TT - Diagnóstico, prevenção e tratamento da doença vascular do aloenxerto. -DEP - 20120920 -PL - Portugal -TA - Rev Port Cardiol -JT - Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de - Cardiologia = Portuguese journal of cardiology : an official journal of the - Portuguese Society of Cardiology -JID - 8710716 -SB - IM -MH - Heart Transplantation/*adverse effects -MH - Humans -MH - Vascular Diseases/diagnosis/*etiology/physiopathology/prevention & - control/therapy -EDAT- 2012/09/25 06:00 -MHDA- 2013/02/27 06:00 -CRDT- 2012/09/25 06:00 -PHST- 2010/12/08 00:00 [received] -PHST- 2012/06/14 00:00 [accepted] -PHST- 2012/09/25 06:00 [entrez] -PHST- 2012/09/25 06:00 [pubmed] -PHST- 2013/02/27 06:00 [medline] -AID - S0870-2551(12)00193-X [pii] -AID - 10.1016/j.repc.2012.08.001 [doi] -PST - ppublish -SO - Rev Port Cardiol. 2012 Nov;31(11):721-30. doi: 10.1016/j.repc.2012.08.001. Epub - 2012 Sep 20. - -PMID- 22868915 -OWN - NLM -STAT- MEDLINE -DCOM- 20130612 -LR - 20121025 -IS - 1432-0878 (Electronic) -IS - 0302-766X (Linking) -VI - 350 -IP - 2 -DP - 2012 Nov -TI - Regenerating cardiac cells: insights from the bench and the clinic. -PG - 189-97 -LID - 10.1007/s00441-012-1484-7 [doi] -AB - A major challenge in cardiovascular regenerative medicine is the development of - novel therapeutic strategies to restore the function of cardiac muscle in the - failing heart. The heart has historically been regarded as a terminally - differentiated organ that does not have the potential to regenerate. This concept - has been updated by the discovery of cardiac stem and progenitor cells that - reside in the adult mammalian heart. Whereas diverse types of adult cardiac stem - or progenitor cells have been described, we still do not know whether these cells - share a common origin. A better understanding of the physiology of cardiac stem - and progenitor cells should advance the successful use of regenerative medicine - as a viable therapy for heart disease. In this review, we summarize current - knowledge of the various adult cardiac stem and progenitor cell types that have - been discovered. We also review clinical trials presently being undertaken with - adult stem cells to repair the injured myocardium in patients with coronary - artery disease. -FAU - Teng, Miao -AU - Teng M -AD - Institute of Burn Research, State Key Laboratory of Trauma, Burns and Combined - Injury, Southwest Hospital, The Third Military Medical University, Chongqing, - 400038, China. -FAU - Zhao, XiaoHui -AU - Zhao X -FAU - Huang, YueSheng -AU - Huang Y -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120807 -PL - Germany -TA - Cell Tissue Res -JT - Cell and tissue research -JID - 0417625 -SB - IM -MH - Animals -MH - Heart Failure/physiopathology -MH - Humans -MH - Mice -MH - Myocytes, Cardiac/*physiology/transplantation -MH - Regenerative Medicine/*methods -MH - Stem Cells/*physiology -EDAT- 2012/08/08 06:00 -MHDA- 2013/06/13 06:00 -CRDT- 2012/08/08 06:00 -PHST- 2012/03/25 00:00 [received] -PHST- 2012/07/13 00:00 [accepted] -PHST- 2012/08/08 06:00 [entrez] -PHST- 2012/08/08 06:00 [pubmed] -PHST- 2013/06/13 06:00 [medline] -AID - 10.1007/s00441-012-1484-7 [doi] -PST - ppublish -SO - Cell Tissue Res. 2012 Nov;350(2):189-97. doi: 10.1007/s00441-012-1484-7. Epub - 2012 Aug 7. - -PMID- 16939836 -OWN - NLM -STAT- MEDLINE -DCOM- 20061121 -LR - 20151119 -IS - 0733-8651 (Print) -IS - 0733-8651 (Linking) -VI - 24 -IP - 3 -DP - 2006 Aug -TI - Electrocardiographic markers of sudden death. -PG - 453-69, x -AB - The 12-lead ECG has limited utility to predict the risk for sudden cardiac death - in common cardiac diseases such as coronary artery disease and idiopathic dilated - cardiomyopathy. However, it is quite useful in diagnosing less common cardiac - conditions that are associated with an increased risk for sudden death. -FAU - Ott, Peter -AU - Ott P -AD - Sarver Heart Center, University of Arizona Health Sciences Center, 1501 N. - Campbell Avenue, Tucson, AZ 85724, USA. ottp@email.arizona.edu -FAU - Marcus, Frank I -AU - Marcus FI -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -RN - 0 (Biomarkers) -SB - IM -MH - Biomarkers -MH - Cardiovascular Diseases/physiopathology -MH - *Death, Sudden, Cardiac -MH - *Electrocardiography -MH - Humans -RF - 78 -EDAT- 2006/08/31 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/08/31 09:00 -PHST- 2006/08/31 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/08/31 09:00 [entrez] -AID - S0733-8651(06)00013-0 [pii] -AID - 10.1016/j.ccl.2006.03.004 [doi] -PST - ppublish -SO - Cardiol Clin. 2006 Aug;24(3):453-69, x. doi: 10.1016/j.ccl.2006.03.004. - -PMID- 20950764 -OWN - NLM -STAT- MEDLINE -DCOM- 20110222 -LR - 20220223 -IS - 1873-1244 (Electronic) -IS - 0899-9007 (Linking) -VI - 26 -IP - 11-12 -DP - 2010 Nov-Dec -TI - Zinc and cardiovascular disease. -PG - 1050-7 -LID - 10.1016/j.nut.2010.03.007 [doi] -AB - Zinc is a vital element in maintaining the normal structure and physiology of - cells. The fact that it has an important role in states of cardiovascular - diseases has been studied and described by several research groups. It appears to - have protective effects in coronary artery disease and cardiomyopathy. - Intracellular zinc plays a critical role in the redox signaling pathway, whereby - certain triggers such as ischemia and infarction lead to release of zinc from - proteins and cause myocardial damage. In such states, replenishing with zinc has - been shown to improve cardiac function and prevent further damage. Thus, the area - of zinc homeostasis is emerging in cardiovascular disease research. The goal of - this report is to review the current knowledge and suggest further avenues of - research. -CI - Copyright © 2010 Elsevier Inc. All rights reserved. -FAU - Little, Peter J -AU - Little PJ -AD - Diabetes and Cell Biology Laboratory, Baker IDI Heart and Diabetes Institute, - Melbourne, Victoria, Australia. -FAU - Bhattacharya, Runa -AU - Bhattacharya R -FAU - Moreyra, Abel E -AU - Moreyra AE -FAU - Korichneva, Irina L -AU - Korichneva IL -LA - eng -GR - R01 HL77305/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Nutrition -JT - Nutrition (Burbank, Los Angeles County, Calif.) -JID - 8802712 -RN - 0 (Cardiotonic Agents) -RN - J41CSQ7QDS (Zinc) -SB - IM -MH - Animals -MH - Arteriosclerosis/physiopathology/prevention & control -MH - Cardiotonic Agents -MH - Cardiovascular Diseases/*physiopathology/prevention & control -MH - Diabetic Cardiomyopathies/physiopathology/prevention & control -MH - Heart Failure/physiopathology/prevention & control -MH - Homeostasis -MH - Humans -MH - Signal Transduction -MH - Zinc/*physiology/therapeutic use -EDAT- 2010/10/19 06:00 -MHDA- 2011/02/23 06:00 -CRDT- 2010/10/19 06:00 -PHST- 2010/01/11 00:00 [received] -PHST- 2010/03/13 00:00 [revised] -PHST- 2010/03/13 00:00 [accepted] -PHST- 2010/10/19 06:00 [entrez] -PHST- 2010/10/19 06:00 [pubmed] -PHST- 2011/02/23 06:00 [medline] -AID - S0899-9007(10)00103-6 [pii] -AID - 10.1016/j.nut.2010.03.007 [doi] -PST - ppublish -SO - Nutrition. 2010 Nov-Dec;26(11-12):1050-7. doi: 10.1016/j.nut.2010.03.007. - -PMID- 20234351 -OWN - NLM -STAT- MEDLINE -DCOM- 20100727 -LR - 20181113 -IS - 1759-5010 (Electronic) -IS - 1759-5002 (Linking) -VI - 7 -IP - 5 -DP - 2010 May -TI - Statin treatment for patients with heart failure. -PG - 249-55 -LID - 10.1038/nrcardio.2010.29 [doi] -AB - Statins may be beneficial for the prevention and treatment of heart failure, as - indicated by large observational studies, small prospective studies, and post hoc - analyses of cardiovascular databases. Two large, prospective, controlled trials - have, however, shown that rosuvastatin has neutral effects on the survival of - patients with chronic heart failure. The benefits of statin treatment seem to - mostly result from their ability to halt disease progression in heart failure, - particularly in patients with coronary artery disease. Based on these results, - statin treatment might only be useful for the prevention of heart failure, and - possibly in patients with new-onset heart failure. This Review highlights data - from observational data analyses as well as from the large prospective trials - investigating the safety and efficacy of statins in patients with heart failure. - The results from these studies and their implications for the timing of - initiating statin therapy in this patient population are also discussed. -FAU - Tang, W H Wilson -AU - Tang WH -AD - Department of Cardiovascular Medicine, Cleveland Clinic Heart and Vascular - Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USA. tangw@ccf.org -FAU - Francis, Gary S -AU - Francis GS -LA - eng -PT - Journal Article -PT - Review -DEP - 20100316 -PL - England -TA - Nat Rev Cardiol -JT - Nature reviews. Cardiology -JID - 101500075 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Cohort Studies -MH - Dose-Response Relationship, Drug -MH - Drug Administration Schedule -MH - Female -MH - Follow-Up Studies -MH - Heart Failure/diagnosis/*drug therapy/*mortality -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Male -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - Severity of Illness Index -MH - Survival Analysis -MH - Treatment Outcome -RF - 49 -EDAT- 2010/03/18 06:00 -MHDA- 2010/07/28 06:00 -CRDT- 2010/03/18 06:00 -PHST- 2010/03/18 06:00 [entrez] -PHST- 2010/03/18 06:00 [pubmed] -PHST- 2010/07/28 06:00 [medline] -AID - nrcardio.2010.29 [pii] -AID - 10.1038/nrcardio.2010.29 [doi] -PST - ppublish -SO - Nat Rev Cardiol. 2010 May;7(5):249-55. doi: 10.1038/nrcardio.2010.29. Epub 2010 - Mar 16. - -PMID- 23512623 -OWN - NLM -STAT- MEDLINE -DCOM- 20130919 -LR - 20211021 -IS - 1534-3170 (Electronic) -IS - 1523-3782 (Linking) -VI - 15 -IP - 5 -DP - 2013 May -TI - Is ischemia the most powerful indicator of myocardial viability? -PG - 354 -LID - 10.1007/s11886-013-0354-6 [doi] -AB - Chronic symptomatic ischemic heart failure remains a major cause of morbidity and - mortality in the adult. Recently, the utility of coronary revascularization in - early management of patients with stable ischemic heart failure has come into - question by several randomized clinical trials. Some of these studies have also - challenged the notion that determination of the predominant state of the - dysfunctional left ventricular myocardium (viable or scarred) may facilitate - identification of patients who would benefit the most from revascularization. - These prospective, randomized, multi-center trials have also exposed many of the - practical impediments to conducting an ideal clinical investigation particularly - in the context of increasingly recognized need for goal-directed and personalized - approaches to management of ischemic heart disease. This review summarizes the - present evidence for an ischemia-guided approach to evaluation and treatment of - chronic ischemic heart disease with left ventricular systolic dysfunction. -FAU - Shirani, Jamshid -AU - Shirani J -AD - Department of Cardiology, St. Luke's University Health Network, 801 Ostrum - Street, Bethlehem, PA, 18015, USA. jamshid.shirani@sluhn.org -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -SB - IM -MH - Heart Failure/etiology -MH - Humans -MH - Myocardial Ischemia/complications/diagnosis/*surgery -MH - *Myocardial Revascularization -MH - Prognosis -MH - Randomized Controlled Trials as Topic -MH - Ventricular Dysfunction, Left/diagnosis/etiology -EDAT- 2013/03/21 06:00 -MHDA- 2013/09/21 06:00 -CRDT- 2013/03/21 06:00 -PHST- 2013/03/21 06:00 [entrez] -PHST- 2013/03/21 06:00 [pubmed] -PHST- 2013/09/21 06:00 [medline] -AID - 10.1007/s11886-013-0354-6 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2013 May;15(5):354. doi: 10.1007/s11886-013-0354-6. - -PMID- 22565537 -OWN - NLM -STAT- MEDLINE -DCOM- 20120724 -LR - 20220325 -IS - 1530-6550 (Print) -IS - 1530-6550 (Linking) -VI - 13 -IP - 1 -DP - 2012 -TI - Sudden cardiac death in women. -PG - e37-42 -LID - 10.3909/ricm0589 [doi] -AB - Women are at lower risk for development of sudden cardiac death (SCD) as compared - with men. Women with SCD tend to have less structural heart disease and preserved - left ventricular systolic function. Coronary artery disease (CAD) is the most - common predictor of SCD in women, as it is in men. However, women with SCD are - less likely to have underlying CAD than men, suggesting the need to identify risk - factors other than CAD or systolic dysfunction for its prediction in women. SCD - risk factors in women include heart failure with preserved left ventricular - systolic function, abnormal sympathetic uptake as assessed by - meta-iodobenzylguanidine uptake, depression, and/or use of antidepressants. This - article reviews SCD in women and discusses areas for future research. -FAU - Simmons, Ashley -AU - Simmons A -AD - University of Kansas Hospital, Kansas City, KS, USA. -FAU - Pimentel, Rhea -AU - Pimentel R -FAU - Lakkireddy, Dhanunjaya -AU - Lakkireddy D -LA - eng -PT - Journal Article -PT - Review -PL - Singapore -TA - Rev Cardiovasc Med -JT - Reviews in cardiovascular medicine -JID - 100960007 -RN - 0 (Antidepressive Agents) -SB - IM -MH - Antidepressive Agents/therapeutic use -MH - Death, Sudden, Cardiac/*etiology/*prevention & control -MH - Defibrillators, Implantable -MH - Depression/complications/drug therapy -MH - *Electric Countershock/instrumentation -MH - Female -MH - Health Status Disparities -MH - Heart Failure/complications/physiopathology -MH - Humans -MH - Male -MH - Prognosis -MH - Risk Assessment -MH - Risk Factors -MH - Sex Factors -MH - Stroke Volume -MH - Sympathetic Nervous System/physiopathology -MH - Ventricular Function, Left -MH - *Women's Health -EDAT- 2012/05/09 06:00 -MHDA- 2012/07/25 06:00 -CRDT- 2012/05/09 06:00 -PHST- 2012/05/09 06:00 [entrez] -PHST- 2012/05/09 06:00 [pubmed] -PHST- 2012/07/25 06:00 [medline] -AID - 10.3909/ricm0589 [doi] -PST - ppublish -SO - Rev Cardiovasc Med. 2012;13(1):e37-42. doi: 10.3909/ricm0589. - -PMID- 21196352 -OWN - NLM -STAT- MEDLINE -DCOM- 20110517 -LR - 20220227 -IS - 1945-0524 (Electronic) -IS - 1945-0516 (Linking) -VI - 3 -IP - 1 -DP - 2011 Jan 1 -TI - Management of type-2 diabetes with anti-platelet therapies: special reference to - aspirin. -PG - 1-15 -AB - Adult onset diabetes currently affects 380 million individuals worldwide and is - expected to affect 380 million by 2025. Major defects contributing to this - complex disease are insulin resistance and beta cell dysfunction. More than 80% - of patients professing to type-2 diabetes are insulin resistant. Recent studies - have shown that the Indian subcontinent ranks very high in the occurrence of - Diabetes and Coronary artery disease (1, 2, 3). Patients with Type 2 diabetes - carry an equivalent cardiovascular risk to that of a non-diabetic individual who - has already experienced a coronary event. The risk of coronary artery disease in - any given population seems to be 2-3 times higher in diabetics than - non-diabetics. Inflammation, platelet activation, endothelial dysfunction and - coagulation are the four processes, whose interplay determines the development of - cardiovascular disease. In this article, we provide a brief overview on platelet - physiology, vascular dysfunction, platelet hyper-function, and the role of - platelet related clinical complications in diabetes mellitus and what is know - about the management of this complex disease with anti-platelet drugs such as - aspirin and Clopidogrel. -FAU - Rao, Gundu H R -AU - Rao GH -AD - Laboratory Medicine and Pathology, Lillehei Heart Institute, University of - Minnesota, Minneapolis, Minnesota 55455, USA. gundurao9@gmail.com -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110101 -PL - Singapore -TA - Front Biosci (Schol Ed) -JT - Frontiers in bioscience (Scholar edition) -JID - 101485241 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Thienopyridines) -RN - 27YG812J1I (Arachidonic Acid) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Arachidonic Acid/metabolism -MH - Aspirin/*therapeutic use -MH - Blood Platelets/*physiology -MH - Clopidogrel -MH - Diabetes Mellitus, Type 2/*complications/*drug therapy -MH - Drug Resistance -MH - Humans -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Thienopyridines/therapeutic use -MH - Ticlopidine/*analogs & derivatives/therapeutic use -MH - Vascular Diseases/etiology/*prevention & control -EDAT- 2011/01/05 06:00 -MHDA- 2011/05/18 06:00 -CRDT- 2011/01/04 06:00 -PHST- 2011/01/04 06:00 [entrez] -PHST- 2011/01/05 06:00 [pubmed] -PHST- 2011/05/18 06:00 [medline] -AID - 127 [pii] -AID - 10.2741/s127 [doi] -PST - epublish -SO - Front Biosci (Schol Ed). 2011 Jan 1;3(1):1-15. doi: 10.2741/s127. - -PMID- 21125978 -OWN - NLM -STAT- MEDLINE -DCOM- 20110104 -LR - 20191111 -IS - 0001-5385 (Print) -IS - 0001-5385 (Linking) -VI - 65 -IP - 5 -DP - 2010 Oct -TI - The effect of CABG on neurocognitive functioning. -PG - 557-64 -AB - Post-operative cognitive decline occurs in 20-70% of the coronary artery bypass - surgery patients during the first week after surgery. After 6 weeks the incidence - declines to 10-40% and remains at this level thereafter.Although the - neuropsychological consequences are subclinical, they can interfere with daily - life. In this paper, we discuss the impact of surgical factors, with a focus on - the use of the heart-lung machine and its intra-operative embolic load. The - pre-morbid cardiac condition of the patient as another underlying mechanism for - cognitive decline is addressed. We also describe the methodological pitfalls in - arriving at an adequate estimation of the prevalence of cognitive decline. Among - these are the definition of cognitive decline, testing intervals, the choice of - cognitive domains and the appropriate use of control groups.We also pay attention - to the relation between cognition, depression and anxiety. Finally, the - ecological validity of this study domain is discussed. It is concluded that (1) - the literature remains undecided on the role of intra-operative emboli and - cognitive decline after surgery. Researchers should focus on the composition, - size and location instead of the absolute number of intra-operative emboli; (2) - growing awareness of neurocognitive decline in chronic vascular disease patients - must challenge both clinicians and investigators.The preoperative cognitive - status can increase the risk for post-operative cognitive decline; (3) - researchers should include--at the least--the core battery as stated in the - Statement of Consensus on assessment of neurobehavioural outcomes after cardiac - surgery. They also should work towards a consensus on the definition of cognitive - decline and the definition of control groups; (4) depression and anxiety as - confounders for postoperative cognitive decline might lead to an overestimation - of cognitive decline at least for the majority of neuropsychological domains; (5) - much more attention should go to the ecological validity of this research. -FAU - Stroobant, Nathalie -AU - Stroobant N -AD - Laboratory for Neuropsychology, Department of Internal Medicine, Neurology - Section, Ghent University, Belgium. Nathalie.Stroobant@Ugent.be -FAU - Van Nooten, Guido -AU - Van Nooten G -FAU - Van Belleghem, Yves -AU - Van Belleghem Y -FAU - Vingerhoets, Guy -AU - Vingerhoets G -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Acta Cardiol -JT - Acta cardiologica -JID - 0370570 -SB - IM -MH - Anxiety/epidemiology -MH - Attention -MH - Cognition Disorders/*epidemiology/etiology/psychology -MH - Coronary Artery Bypass/*adverse effects -MH - Coronary Artery Bypass, Off-Pump -MH - Depression/epidemiology -MH - Humans -MH - Intracranial Embolism/epidemiology -MH - Memory Disorders/epidemiology -MH - Neuropsychological Tests -EDAT- 2010/12/04 06:00 -MHDA- 2011/01/05 06:00 -CRDT- 2010/12/04 06:00 -PHST- 2010/12/04 06:00 [entrez] -PHST- 2010/12/04 06:00 [pubmed] -PHST- 2011/01/05 06:00 [medline] -AID - 10.1080/ac.65.5.2056243 [doi] -PST - ppublish -SO - Acta Cardiol. 2010 Oct;65(5):557-64. doi: 10.1080/ac.65.5.2056243. - -PMID- 21105969 -OWN - NLM -STAT- MEDLINE -DCOM- 20111207 -LR - 20151119 -IS - 1742-1241 (Electronic) -IS - 1368-5031 (Linking) -VI - 65 -IP - 1 -DP - 2011 Jan -TI - 'Trig-onometry': non-high-density lipoprotein cholesterol as a therapeutic target - in dyslipidaemia. -PG - 82-101 -LID - 10.1111/j.1742-1241.2010.02547.x [doi] -AB - Targeting elevations in low-density lipoprotein cholesterol (LDL-C) remains the - cornerstone of cardiovascular prevention. However, this fraction does not - adequately capture elevated triglyceride-rich lipoproteins (TRLs; e.g. - intermediate-density lipoprotein, very low density lipoprotein) in certain - patients with metabolic syndrome or diabetic dyslipidaemia. Many such individuals - have residual cardiovascular risk that might be lipid/lipoprotein related despite - therapy with first-line agents (statins). Epidemiological evidence encompassing > - 100,000 persons supports the contention that non-high-density lipoprotein - cholesterol (non-HDL-C) is a superior risk factor vs. LDL-C for incident coronary - heart disease (CHD) in certain patient populations. In studies with clinical - end-points evaluated in the current article, a 1:1 to 1:3 relationship was - observed between reductions in non-HDL-C and in the relative risk of CHD after - long-term treatment with statins, niacin (nicotinic acid) and fibric-acid - derivatives (fibrates); this relationship increased to 1:5 to 1:10 in smaller - subgroups of patients with elevated triglycerides and low HDL-C levels. Treatment - with statin-, niacin-, fibrate-, ezetimibe-, and omega 3 fatty acid-containing - regimens reduced non-HDL-C by approximately 9-65%. In a range of clinical trials, - long-term treatment with these agents also significantly decreased the incidence - of clinical/angiographic/imaging efficacy outcome variables. For patients with - dyslipidaemia, consensus guidelines have established non-HDL-C treatment targets - 30 mg/dl higher than LDL-C goals. Ongoing prospective randomised controlled - trials should help to resolve controversies concerning (i) the clinical utility - of targeting non-HDL-C in patients with dyslipidaemia; (ii) the most efficacious - and well-tolerated therapies to reduce non-HDL-C (e.g. combination regimens); and - (iii) associations between such reductions and clinical, angiographic, and/or - imaging end-points. -CI - © 2010 Blackwell Publishing Ltd. -FAU - Jacobson, T A -AU - Jacobson TA -AD - Office of Health Promotion and Disease Prevention, Department of Medicine, Emory - University School of Medicine, Atlanta, GA 30303, USA. tjaco02@emory.edu -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20101124 -PL - United States -TA - Int J Clin Pract -JT - International journal of clinical practice -JID - 9712381 -RN - 0 (Azetidines) -RN - 0 (Cholesterol, HDL) -RN - 0 (Fatty Acids, Omega-3) -RN - 0 (Fibric Acids) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Hypolipidemic Agents) -RN - 2679MF687A (Niacin) -RN - EOR26LQQ24 (Ezetimibe) -SB - IM -CIN - Int J Clin Pract. 2011 Jan;65(1):3-5. doi: 10.1111/j.1742-1241.2010.02566.x. - PMID: 21155938 -MH - Adult -MH - Azetidines/therapeutic use -MH - Cardiovascular Diseases/blood/prevention & control -MH - Cholesterol, HDL/*antagonists & inhibitors -MH - Dyslipidemias/*drug therapy -MH - Ezetimibe -MH - Fatty Acids, Omega-3/therapeutic use -MH - Female -MH - Fibric Acids/therapeutic use -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Hypolipidemic Agents/*therapeutic use -MH - Male -MH - Middle Aged -MH - Niacin/therapeutic use -MH - Practice Guidelines as Topic -MH - Risk Factors -MH - Young Adult -EDAT- 2010/11/26 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2010/11/26 06:00 -PHST- 2010/11/26 06:00 [entrez] -PHST- 2010/11/26 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -AID - 10.1111/j.1742-1241.2010.02547.x [doi] -PST - ppublish -SO - Int J Clin Pract. 2011 Jan;65(1):82-101. doi: 10.1111/j.1742-1241.2010.02547.x. - Epub 2010 Nov 24. - -PMID- 20519304 -OWN - NLM -STAT- MEDLINE -DCOM- 20100914 -LR - 20100603 -IS - 1816-5370 (Electronic) -IS - 0218-4923 (Linking) -VI - 18 -IP - 3 -DP - 2010 Jun -TI - Global aspects of cardiothoracic surgery with focus on developing countries. -PG - 299-310 -LID - 10.1177/0218492310370060 [doi] -AB - The incidence and prevalence of cardiothoracic disease continue to increase - globally, especially in emerging economies and developing countries. - Cardiothoracic surgery is also growing despite limited access, availability of - surgical centers, political and cost issues. The increase in atherosclerotic - coronary artery disease, rheumatic heart disease, congenital heart disease, - trauma, and thoracic malignancies is a more urgent problem than realized in these - emerging economies and developing countries, or low- and middle-income countries. - A determined focus and cooperation between the preventive and curative elements - of care is warranted. This represents a paradigm shift to develop a consensus - that fosters a multi-integrated disease-specific approach that includes - prevention, promotion, diagnosis, treatment, and rehabilitation. In addition, the - concept or acceptance of surgery as a necessary component of public health policy - is critical to improving overall global healthcare. -FAU - Pezzella, A Thomas -AU - Pezzella AT -AD - International Children's Heart Fund, 17 Shamrock Street, Worcester, MA 01605, - USA. atpezzella@hotmail.com -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Asian Cardiovasc Thorac Ann -JT - Asian cardiovascular & thoracic annals -JID - 9503417 -SB - IM -MH - Cardiac Surgical Procedures/economics/education/*trends -MH - Clinical Competence -MH - *Developing Countries/economics -MH - Education, Medical/trends -MH - Health Care Costs/trends -MH - Health Policy/trends -MH - Health Services Accessibility/trends -MH - Humans -MH - *Internationality -MH - Quality of Health Care/trends -MH - Thoracic Surgical Procedures/economics/education/*trends -RF - 87 -EDAT- 2010/06/04 06:00 -MHDA- 2010/09/15 06:00 -CRDT- 2010/06/04 06:00 -PHST- 2010/06/04 06:00 [entrez] -PHST- 2010/06/04 06:00 [pubmed] -PHST- 2010/09/15 06:00 [medline] -AID - 18/3/299 [pii] -AID - 10.1177/0218492310370060 [doi] -PST - ppublish -SO - Asian Cardiovasc Thorac Ann. 2010 Jun;18(3):299-310. doi: - 10.1177/0218492310370060. - -PMID- 23549239 -OWN - NLM -STAT- MEDLINE -DCOM- 20140224 -LR - 20181202 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 28 -IP - 4 -DP - 2013 Jul -TI - The role of clopidogrel in the management of ischemic heart disease. -PG - 381-8 -LID - 10.1097/HCO.0b013e3283606957 [doi] -AB - PURPOSE OF REVIEW: Placebo-controlled randomized trials have demonstrated the - efficacy of clopidogrel in combination with aspirin across a broad range of - clinical presentations. Recent trials have addressed several remaining issues - regarding clopidogrel therapy. RECENT FINDINGS: Three randomized trials examined - the role of platelet function testing (PFT) in clopidogrel-treated patients. The - results do not support the use of PFT to adjust clopidogrel dose after - percutaneous coronary intervention (PCI), particularly in patients with stable - angina or ischemia, in whom event rates are low irrespective of on-treatment - reactivity. Doses greater than clopidogrel 150  mg daily are required to - sufficiently overcome high reactivity in CYP2C19 loss-of-function (LOF) allele - carriers. Clopidogrel response variability also influences the time to platelet - recovery after drug discontinuation, and a proof-of-principle study supports the - concept of using PFT for surgical timing. Unlike its efficacy in the setting of - acute coronary syndrome (ACS) and PCI, prasugrel was not superior to clopidogrel - in medically treated patients recovering from ACS. SUMMARY: Current data do not - support routine PFT to guide antiplatelet therapy in patients undergoing - nonurgent PCI. The role of PFT to optimize therapy in ACS patients remains - unaddressed, and further study is needed to confirm its promise in guiding - surgical timing in patients who have discontinued therapy. Clopidogrel remains an - important therapeutic option for patients presenting after an ACS who did not - undergo initial revascularization. -FAU - Homan, David J -AU - Homan DJ -AD - Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, California, USA. -FAU - Price, Matthew J -AU - Price MJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -RN - 0 (Platelet Aggregation Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - EC 1.14.14.1 (Aryl Hydrocarbon Hydroxylases) -RN - EC 1.14.14.1 (CYP2C19 protein, human) -RN - EC 1.14.14.1 (Cytochrome P-450 CYP2C19) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Acute Coronary Syndrome/*drug therapy -MH - Aryl Hydrocarbon Hydroxylases/genetics/metabolism -MH - Clopidogrel -MH - Cytochrome P-450 CYP2C19 -MH - Humans -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - *Platelet Function Tests -MH - Practice Guidelines as Topic -MH - Preoperative Care -MH - Randomized Controlled Trials as Topic -MH - Ticlopidine/*analogs & derivatives/therapeutic use -EDAT- 2013/04/04 06:00 -MHDA- 2014/02/25 06:00 -CRDT- 2013/04/04 06:00 -PHST- 2013/04/04 06:00 [entrez] -PHST- 2013/04/04 06:00 [pubmed] -PHST- 2014/02/25 06:00 [medline] -AID - 10.1097/HCO.0b013e3283606957 [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2013 Jul;28(4):381-8. doi: 10.1097/HCO.0b013e3283606957. - -PMID- 19672592 -OWN - NLM -STAT- MEDLINE -DCOM- 20110614 -LR - 20211020 -IS - 1619-7089 (Electronic) -IS - 1619-7070 (Linking) -VI - 36 -IP - 12 -DP - 2009 Dec -TI - Nuclear cardiology and heart failure. -PG - 2068-80 -LID - 10.1007/s00259-009-1246-2 [doi] -AB - The prevalence of heart failure in the adult population is increasing. It varies - between 1% and 2%, although it mainly affects elderly people (6-10% of people - over the age of 65 years will develop heart failure). The syndrome of heart - failure arises as a consequence of an abnormality in cardiac structure, function, - rhythm, or conduction. Coronary artery disease is the leading cause of heart - failure and it accounts for this disorder in 60-70% of all patients affected. - Nuclear techniques provide unique information on left ventricular function and - perfusion by gated-single photon emission tomography (SPECT). Myocardial - viability can be assessed by both SPECT and PET imaging. Finally, autonomic - dysfunction has been shown to increase the risk of death in patients with heart - disease and this may be applicable to all patients with cardiac disease - regardless of aetiology. MIBG scanning has a very promising prognostic value in - patients with heart failure. -FAU - Giubbini, Raffaele -AU - Giubbini R -AD - Department of Nuclear Medicine, University of Brescia, Piazza Spedali Civili 1, - 25123 Brescia, Italy. giubbini@med.unibs.it -FAU - Milan, Elisa -AU - Milan E -FAU - Bertagna, Francesco -AU - Bertagna F -FAU - Mut, Fernando -AU - Mut F -FAU - Metra, Marco -AU - Metra M -FAU - Rodella, Carlo -AU - Rodella C -FAU - Dondi, Maurizio -AU - Dondi M -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Eur J Nucl Med Mol Imaging -JT - European journal of nuclear medicine and molecular imaging -JID - 101140988 -SB - IM -MH - Cardiology/*methods -MH - Diagnostic Imaging -MH - Heart Failure/*diagnosis/diagnostic imaging/pathology/physiopathology -MH - Humans -MH - Nuclear Medicine/*methods -MH - Radionuclide Imaging -MH - Tissue Survival -MH - Ventricular Dysfunction, Left/diagnosis/diagnostic - imaging/pathology/physiopathology -EDAT- 2009/08/13 09:00 -MHDA- 2011/06/15 06:00 -CRDT- 2009/08/13 09:00 -PHST- 2009/01/30 00:00 [received] -PHST- 2009/07/26 00:00 [accepted] -PHST- 2009/08/13 09:00 [entrez] -PHST- 2009/08/13 09:00 [pubmed] -PHST- 2011/06/15 06:00 [medline] -AID - 10.1007/s00259-009-1246-2 [doi] -PST - ppublish -SO - Eur J Nucl Med Mol Imaging. 2009 Dec;36(12):2068-80. doi: - 10.1007/s00259-009-1246-2. - -PMID- 22489721 -OWN - NLM -STAT- MEDLINE -DCOM- 20120911 -LR - 20220310 -IS - 1875-533X (Electronic) -IS - 0929-8673 (Linking) -VI - 19 -IP - 16 -DP - 2012 -TI - The role of microRNAs in cardiovascular disease. -PG - 2605-10 -AB - Cardiovascular disease, which is multifactorial and can be influenced by a - multitude of environmental and heritable risk factors, remains a major health - problem, even though its pathophysiology is far from been elucidated. Discovered - just over a decade ago, microRNAs comprise short, non-coding RNAs, which have - evoked a great deal of interest, due to their importance for many aspects of - homeostasis and disease. Hundreds of different microRNAs are constantly being - reported in various organisms. According to a growing body of literature, they - have been implicated in the regulation of human physiological processes. More - specifically, miRNAs are expressed in the cardiovascular system and could have - crucial roles in normal development and physiology, as well as in disease - development. Furthermore, they have been shown to participate in cardiovascular - disease pathogenesis including atherosclerosis, coronary artery disease, - myocardial infarction, heart failure and cardiac arrhythmias. In contrast to our - original thought, miRNAs exist in circulating blood and are relatively stable, - thus, they could be proved useful as biomarkers in that state. Understanding the - underlying mechanisms, in which these major regulatory gene families are - implicated, will provide novel opportunities for diagnosis and therapy of - cardiovascular diseases. -FAU - Papageorgiou, N -AU - Papageorgiou N -AD - 1st Cardiology Unit, Hippokration Hospital, Athens University Medical School, - Greece. drnpapageorgiou@yahoo.com -FAU - Tousoulis, D -AU - Tousoulis D -FAU - Androulakis, E -AU - Androulakis E -FAU - Siasos, G -AU - Siasos G -FAU - Briasoulis, A -AU - Briasoulis A -FAU - Vogiatzi, G -AU - Vogiatzi G -FAU - Kampoli, A-M -AU - Kampoli AM -FAU - Tsiamis, E -AU - Tsiamis E -FAU - Tentolouris, C -AU - Tentolouris C -FAU - Stefanadis, C -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (MicroRNAs) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*genetics -MH - Humans -MH - MicroRNAs/*genetics -EDAT- 2012/04/12 06:00 -MHDA- 2012/09/12 06:00 -CRDT- 2012/04/12 06:00 -PHST- 2011/09/15 00:00 [received] -PHST- 2011/11/12 00:00 [revised] -PHST- 2011/12/03 00:00 [accepted] -PHST- 2012/04/12 06:00 [entrez] -PHST- 2012/04/12 06:00 [pubmed] -PHST- 2012/09/12 06:00 [medline] -AID - CDT-EPUB-20120206-001 [pii] -AID - 10.2174/092986712800493048 [doi] -PST - ppublish -SO - Curr Med Chem. 2012;19(16):2605-10. doi: 10.2174/092986712800493048. - -PMID- 17226010 -OWN - NLM -STAT- MEDLINE -DCOM- 20070926 -LR - 20181113 -IS - 0020-9554 (Print) -IS - 0020-9554 (Linking) -VI - 48 -IP - 3 -DP - 2007 Mar -TI - [The heart in rheumatic diseases]. -PG - 284-9 -AB - As systemic immunological disorders inflammatory rheumatic diseases potentially - involve organs and structures beyond the musculo-skeletal system including skin - and blood vessels. Various neurological, renal, pulmonary, hematological and - cardiac manifestations contribute to the broad clinical picture of connective - tissue diseases and vasculitides. Regarding cardiac disease all structures of the - heart may be affected. Pericarditis in lupus, mitral valve changes in the - antiphospholipid syndrome, myocarditis and coronary artery stenosis in the - systemic vasculitides are typical examples in systemic rheumatic diseases. Beyond - this, pulmonary hypertension in systemic sclerosis or congenital heart block in - newborns of lupus patients are further cardiac issues. Since better treatment - options led to more long-lasting courses in connective tissue diseases, - cardiovascular complications as a consequence of chronic disease- and - therapy-related damage gain increasing attention. -FAU - Specker, C -AU - Specker C -AD - Klinik für Rheumatologie & Klinische Immunologie, Katholisches Krankenhaus St. - Josef, Zentrum für Innere Medizin der Kliniken Essen Süd, Essen, Deutschland. - specker@rheumanet.org -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Das Herz bei rheumatologischen Erkrankungen. -PL - Germany -TA - Internist (Berl) -JT - Der Internist -JID - 0264620 -SB - IM -MH - Arthritis, Rheumatoid/complications/diagnosis -MH - Connective Tissue Diseases/*complications -MH - Heart Diseases/*diagnosis/etiology -MH - Humans -MH - Lupus Erythematosus, Systemic/complications/diagnosis -MH - Rheumatic Diseases/complications/*diagnosis -MH - Scleroderma, Systemic/complications/diagnosis -MH - Spondylitis, Ankylosing/complications/diagnosis -MH - Vasculitis/complications/diagnosis -RF - 36 -EDAT- 2007/01/18 09:00 -MHDA- 2007/09/27 09:00 -CRDT- 2007/01/18 09:00 -PHST- 2007/01/18 09:00 [pubmed] -PHST- 2007/09/27 09:00 [medline] -PHST- 2007/01/18 09:00 [entrez] -AID - 10.1007/s00108-006-1778-5 [doi] -PST - ppublish -SO - Internist (Berl). 2007 Mar;48(3):284-9. doi: 10.1007/s00108-006-1778-5. - -PMID- 20934984 -OWN - NLM -STAT- MEDLINE -DCOM- 20110506 -LR - 20250624 -IS - 1460-2393 (Electronic) -IS - 1460-2393 (Linking) -VI - 104 -IP - 2 -DP - 2011 Feb -TI - Efficacy and safety of statin treatment for cardiovascular disease: a network - meta-analysis of 170,255 patients from 76 randomized trials. -PG - 109-24 -LID - 10.1093/qjmed/hcq165 [doi] -AB - BACKGROUND: Statins represent the largest selling class of cardiovascular drug in - the world. Previous randomized trials (RCTs) have demonstrated important clinical - benefits with statin therapy. AIM: We combined evidence from all RCTs comparing a - statin with placebo or usual care among patients with and without prior coronary - heart disease (CHD) to determine clinical outcomes. DESIGN: We searched - independently, in duplicate, 12 electronic databases (from inception to August - 2010), including full text journal content databases, to identify all statin - versus inert control RCTs. We included RCTs of any statin versus any non-drug - control in any populations. We abstracted data in duplicate on reported major - clinical events and adverse events. We performed a random-effects meta-analysis - and meta-regression. We performed a mixed treatment comparison using Bayesian - methods. RESULTS: We included a total of 76 RCTs involving 170,255 participants. - There were a total of 14,878 deaths. Statin therapy reduced all-cause mortality, - Relative Risk (RR) 0.90 [95% confidence interval (CI) 0.86-0.94, P ≤ 0.0001, - I(2)=17%]; cardiovascular disease (CVD) mortality (RR 0.80, 95% CI 0.74-0.87, - P<0.0001, I(2)=27%); fatal myocardial infarction (MI) (RR 0.82, 95% CI 0.75-0.91, - P<0.0001, I(2)=21%); non-fatal MI (RR 0.74, 95% CI 0.67-0.81, P ≤ 0.001, - I(2)=45%); revascularization (RR 0.76, 95% CI 0.70-0.81, P ≤ 0.0001); and a - composite of fatal and non-fatal strokes (0.86, 95% CI 0.78-0.95, P=0.004, - I(2)=41%). Adverse events were generally mild, but 17 RCTs reported on increased - risk of development of incident diabetes [Odds Ratio (OR) 1.09; 95% CI 1.02-1.17, - P=0.001, I(2)=11%]. Studies did not yield important differences across - populations. We did not find any differing treatment effects between statins. - DISCUSSION: Statin therapies offer clear benefits across broad populations. As - generic formulations become more available efforts to expand access should be a - priority. -FAU - Mills, E J -AU - Mills EJ -AD - Faculty of Health Sciences, University of Ottawa, Ottawa, Canada. - Edward.mills@uottawa.ca -FAU - Wu, P -AU - Wu P -FAU - Chong, G -AU - Chong G -FAU - Ghement, I -AU - Ghement I -FAU - Singh, S -AU - Singh S -FAU - Akl, E A -AU - Akl EA -FAU - Eyawo, O -AU - Eyawo O -FAU - Guyatt, G -AU - Guyatt G -FAU - Berwanger, O -AU - Berwanger O -FAU - Briel, M -AU - Briel M -LA - eng -PT - Journal Article -PT - Network Meta-Analysis -PT - Review -DEP - 20101007 -PL - England -TA - QJM -JT - QJM : monthly journal of the Association of Physicians -JID - 9438285 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -CIN - QJM. 2011 Feb;104(2):174-8. doi: 10.1093/qjmed/hcq230. PMID: 21118868 -MH - Aged -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - *Cardiovascular Diseases/mortality/prevention & control -MH - Diabetes Mellitus, Type 2/chemically induced -MH - *Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects/therapeutic use -MH - Randomized Controlled Trials as Topic/methods/standards -MH - Research Design -MH - Risk Factors -EDAT- 2010/10/12 06:00 -MHDA- 2011/05/07 06:00 -CRDT- 2010/10/12 06:00 -PHST- 2010/10/12 06:00 [entrez] -PHST- 2010/10/12 06:00 [pubmed] -PHST- 2011/05/07 06:00 [medline] -AID - hcq165 [pii] -AID - 10.1093/qjmed/hcq165 [doi] -PST - ppublish -SO - QJM. 2011 Feb;104(2):109-24. doi: 10.1093/qjmed/hcq165. Epub 2010 Oct 7. - -PMID- 17488145 -OWN - NLM -STAT- MEDLINE -DCOM- 20070628 -LR - 20220317 -IS - 0012-6667 (Print) -IS - 0012-6667 (Linking) -VI - 67 -IP - 7 -DP - 2007 -TI - Approaches to prevention of cardiovascular complications and events in diabetes - mellitus. -PG - 997-1026 -AB - Diabetes mellitus affects about 8% of the adult population. The estimated number - of patients with diabetes, presently about 170 million people, is expected to - increase by 50-70% within the next 25 years. Diabetes is an important component - of the complex of 'common' cardiovascular risk factors, and is responsible for - acceleration and worsening of atherothrombosis. Major cardiovascular events cause - about 80% of the total mortality in diabetic patients. Diabetes also induces - peculiar microangiopathic changes leading to diabetic nephropathy conducive to - end-stage renal failure, and to diabetic retinopathy that may progress to vision - loss and blindness. In terms of major cardiovascular events, coronary heart - disease and ischaemic stroke are the main causes of morbidity and mortality in - diabetic patients. Peripheral arterial disease frequently occurs, and is more - likely to be conducive to critical limb ischaemia and amputation than in the - absence of diabetes. Although there are a number of differences in the - pathogenesis and clinical features of diabetic macroangiopathy and - microangiopathy, these two entities often coexist and induce mutually worsening - effects. Endothelial injury, dysfunction and damage are common starting points - for both conditions. Causes of endothelial injury can be distinguished into those - 'common' to nondiabetic atherothrombosis, such as hypertension, dyslipidaemia, - smoking, hypercoagulability and platelet activation; and those more specific and - in some cases 'unique' to diabetes and directly related to the metabolic - derangement of the disease, such as (i) desulfation of glycosaminoglycans (GAGs) - of the vascular matrix; (ii) formation of advanced glycation end-products (AGE) - and their endothelial receptors (RAGE); (iii) oxidative and reductive stress; - (iv) decline in nitric oxide production; (v) activation of the renin-angiotensin - aldosterone system (RAAS); and (vi) endothelial inflammation caused by glucose, - insulin, insulin precursors and AGE/RAGE. Prevention of major cardiovascular - events with the antithrombotic agent aspirin (acetylsalicylic acid) is widely - recommended, but reportedly underutilised in patients with diabetes. However, - some data suggest that aspirin may be less effective than expected in preventing - cardiovascular events and especially mortality in patients with diabetes, as well - as in slowing progression of retinopathy. In contrast, a recent study found - picotamide, a direct thromboxane inhibitor, to be superior to aspirin in diabetic - patients. Clopidogrel was either equivalent or less active in diabetic versus - nondiabetic patients, depending upon different clinical settings.Recent studies - have shown that some GAG compounds are able to reduce micro- and macroalbuminuria - in diabetic nephropathy, and hard exudates in diabetic retinopathy, but it is as - yet unknown whether these agents also influence the natural history of - microvascular complications of diabetes. Lifestyle changes and physical exercise - are also essential in preventing cardiovascular events in diabetic patients. - Available data on the control of the metabolic state and the main risk factors - show that careful adjustment of blood sugar and glycated haemoglobin is more - effective in counteracting microvascular damage than in preventing major - cardiovascular events. The latter objective requires a more comprehensive - approach to the whole constellation of risk factors both specific for diabetes - and common to atherothrombosis. This approach includes lifestyle modifications, - such as dietary changes and smoking cessation and the use of HMG-CoA reductase - inhibitors (statins), which are able to correct the lipid status and to prevent - major cardiovascular events independently of the baseline lipidaemic or - cardiovascular status. Tight control of hypertension is essential to reduce not - only major cardiovascular events but also microvascular complications. Among - antihypertensive measures, blockade of the RAAS by means of ACE inhibitors or - angiotensin II receptor antagonists recently emerged as a potentially polyvalent - approach, not only for treating hypertension and reducing cardiovascular events, - but also to prevent or reduce albuminuria, counteract diabetic nephropathy and - lower the occurrence of new type 2 diabetes in individuals at risk. -FAU - Coccheri, Sergio -AU - Coccheri S -AD - University of Bologna Medical School, Bologna, Italy. coccheris.angio@libero.it -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Drugs -JT - Drugs -JID - 7600076 -RN - 0 (Fibrinolytic Agents) -RN - 0 (Hypoglycemic Agents) -SB - IM -MH - *Cardiovascular Diseases/etiology/prevention & control/therapy -MH - Diabetes Complications/*prevention & control -MH - Diabetes Mellitus/*drug therapy/*physiopathology -MH - Fibrinolytic Agents/therapeutic use -MH - Humans -MH - Hypoglycemic Agents/therapeutic use -RF - 242 -EDAT- 2007/05/10 09:00 -MHDA- 2007/06/29 09:00 -CRDT- 2007/05/10 09:00 -PHST- 2007/05/10 09:00 [pubmed] -PHST- 2007/06/29 09:00 [medline] -PHST- 2007/05/10 09:00 [entrez] -AID - 6775 [pii] -AID - 10.2165/00003495-200767070-00005 [doi] -PST - ppublish -SO - Drugs. 2007;67(7):997-1026. doi: 10.2165/00003495-200767070-00005. - -PMID- 21090831 -OWN - NLM -STAT- MEDLINE -DCOM- 20110208 -LR - 20151119 -IS - 1175-3277 (Print) -IS - 1175-3277 (Linking) -VI - 10 -IP - 6 -DP - 2010 -TI - Rosuvastatin: a review of its use in the prevention of cardiovascular disease in - apparently healthy women or men with normal LDL-C levels and elevated hsCRP - levels. -PG - 383-400 -LID - 10.2165/11204600-000000000-00000 [doi] -AB - Rosuvastatin (Crestor®) is an HMG-CoA reductase inhibitor (statin) that has both - lipid-lowering and anti-inflammatory effects. The drug has various indications in - the US, including the primary prevention of cardiovascular disease (CVD) in - patients with no clinical evidence of coronary heart disease who are at increased - risk of CVD based on their age, a high-sensitivity C-reactive protein (hsCRP) - level of ≥2 mg/L, and at least one other CVD risk factor. The efficacy of - rosuvastatin in apparently healthy women (aged ≥60 years) or men (aged ≥50 years) - with normal low-density lipoprotein cholesterol (LDL-C) levels and elevated hsCRP - levels was demonstrated in the large, randomized, double-blind, multinational, - JUPITER trial. Relative to placebo, rosuvastatin 20 mg once daily for a median - follow-up of 1.9 years significantly reduced the occurrence of first major - cardiovascular events in this trial (primary endpoint). A between-group - difference in favor of rosuvastatin was also demonstrated for various other - endpoints, including overall deaths and the nonatherothrombotic endpoint of - venous thromboembolism. Rosuvastatin remained more effective than placebo when - primary endpoint results were stratified according to various baseline factors, - including in patient subgroups thought to be at low risk of CVD. In addition, - rosuvastatin was associated with reductions in LDL-C and hsCRP levels, and these - reductions appeared to occur independently of each other. The greatest clinical - benefit was observed in rosuvastatin recipients achieving an LDL-C level of - <1.8 mmol/L (<70 mg/dL) and an hsCRP level of <2 mg/L or, even more so, <1 mg/L. - Rosuvastatin was well tolerated in the JUPITER trial, with most adverse events - being mild to moderate in severity. Myalgia, arthralgia, constipation, and nausea - were the most commonly occurring treatment-related adverse events, and the - incidence of monitored adverse events and laboratory measurements was generally - similar in the rosuvastatin and placebo groups. It is not yet known whether the - mechanism of benefit of rosuvastatin is via lipid effects, anti-inflammatory - effects, or a mixture of both, and the use of rosuvastatin solely on the basis of - elevated hsCRP levels is controversial. Nonetheless, the drug remains an - important pharmacologic option in the prevention of CVD, and has demonstrated - efficacy in preventing major cardiovascular events in apparently healthy women - (aged ≥60 years) or men (aged ≥50 years) with normal LDL-C levels and elevated - hsCRP levels. -FAU - Carter, Natalie J -AU - Carter NJ -AD - Adis, a Wolters Kluwer Business, Auckland, New Zealand. demail@adis.co.nz -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -RN - 0 (Cholesterol, LDL) -RN - 0 (Fluorobenzenes) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Pyrimidines) -RN - 0 (Sulfonamides) -RN - 83MVU38M7Q (Rosuvastatin Calcium) -RN - 9007-41-4 (C-Reactive Protein) -SB - IM -MH - C-Reactive Protein/*analysis -MH - Cardiovascular Diseases/*prevention & control -MH - Cholesterol, LDL/*blood -MH - Female -MH - Fluorobenzenes/adverse effects/pharmacokinetics/pharmacology/*therapeutic use -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Male -MH - Pyrimidines/adverse effects/pharmacokinetics/pharmacology/*therapeutic use -MH - Rosuvastatin Calcium -MH - Sulfonamides/adverse effects/pharmacokinetics/pharmacology/*therapeutic use -EDAT- 2010/11/26 06:00 -MHDA- 2011/02/09 06:00 -CRDT- 2010/11/25 06:00 -PHST- 2010/11/25 06:00 [entrez] -PHST- 2010/11/26 06:00 [pubmed] -PHST- 2011/02/09 06:00 [medline] -AID - 5 [pii] -AID - 10.2165/11204600-000000000-00000 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2010;10(6):383-400. doi: 10.2165/11204600-000000000-00000. - -PMID- 19026018 -OWN - NLM -STAT- MEDLINE -DCOM- 20090303 -LR - 20220408 -IS - 0112-1642 (Print) -IS - 0112-1642 (Linking) -VI - 38 -IP - 12 -DP - 2008 -TI - Exercise, vascular wall and cardiovascular diseases: an update (Part 1). -PG - 1009-24 -LID - 10.2165/00007256-200838120-00005 [doi] -AB - Cardiovascular disease (CVD) remains the leading cause of morbidity and premature - mortality in both women and men in most industrialized countries, and has for - some time also established a prominent role in developing nations. In fact, - obesity, diabetes mellitus and hypertension are now commonplace even in children - and youths. Regular exercise is rapidly gaining widespread advocacy as a - preventative measure in schools, medical circles and in the popular media. There - is overwhelming evidence garnered from a number of sources, including - epidemiological, prospective cohort and intervention studies, suggesting that CVD - is largely a disease associated with physical inactivity. A rapidly advancing - body of human and animal data confirms an important beneficial role for exercise - in the prevention and treatment of CVD. In Part 1 of this review we discuss the - impact of exercise on CVD, and we highlight the effects of exercise on (i) - endothelial function by regulation of endothelial genes mediating oxidative - metabolism, inflammation, apoptosis, cellular growth and proliferation, increased - superoxide dismutase (SOD)-1, down-regulation of p67phox, changes in - intracellular calcium level, increased vascular endothelial nitric oxide synthase - (eNOS), expression and eNOS Ser-1177 phosphorylation; (ii) vascular smooth muscle - function by either an increased affinity of the Ca2+ extrusion mechanism or an - augmented Ca2+ buffering system by the superficial sarcoplasmic reticulum to - increase Ca2+ sequestration, increase in K+ channel activity and/or expression, - and increase in L-type Ca2+ current density; (iii) antioxidant systems by - elevation of Mn-SOD, Cu/Zn-SOD and catalase, increases in glutathione peroxidase - activity and activation of vascular nicotinamide adenine dinucleotide phosphate - [(NAD(P)H] oxidase and p22phox expression; (iv) heat shock protein (HSP) - expression by stimulating HSP70 expression in myocardium, skeletal muscle and - even in human leucocytes, probably through heat shock transcription factor 1 - activity; (v) inflammation by reducing serum inflammatory cytokines such as - high-sensitivity C-reactive protein (hCRP), interleukin (IL)-6, IL-18 and tumour - necrosis factor-alpha and by regulating Toll-like receptor 4 pathway. Exercise - also alters vascular remodelling, which involves two forms of vessel growth - including angiogenesis and arteriogenesis. Angiogenesis refers to the formation - of new capillary networks. Arteriogenesis refers to the growth of pre-existent - collateral arterioles leading to formation of large conductance arteries that are - well capable to compensate for the loss of function of occluded arteries. Another - aim of this review is to focus on exercise-related cardiovascular protection - against CVD and associated risk factors such as aging, coronary heart disease, - hypertension, heart failure, diabetes mellitus and peripheral arterial diseases - mediated by vascular remodelling. Lastly, this review examines the benefits of - exercise in mitigating pre-eclampsia during pregnancy by mechanisms that include - improved blood flow, reduced blood pressure, enhanced placental growth and - vascularity, increased activity of antioxidant enzymes, reduced oxidative stress - and restored vascular endothelial dysfunction. -FAU - Leung, Fung Ping -AU - Leung FP -AD - Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong - Kong, China. christinaleung@cuhk.edu.hk -FAU - Yung, Lai Ming -AU - Yung LM -FAU - Laher, Ismail -AU - Laher I -FAU - Yao, Xiaoqiang -AU - Yao X -FAU - Chen, Zhen Yu -AU - Chen ZY -FAU - Huang, Yu -AU - Huang Y -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - New Zealand -TA - Sports Med -JT - Sports medicine (Auckland, N.Z.) -JID - 8412297 -RN - 0 (Antioxidants) -RN - 0 (Heat-Shock Proteins) -SB - IM -MH - Antioxidants/physiology -MH - Cardiovascular Diseases/metabolism/physiopathology/*prevention & control -MH - Endothelium, Vascular/metabolism/*physiology -MH - Exercise/*physiology -MH - Female -MH - Heat-Shock Proteins/metabolism -MH - Humans -MH - Inflammation/metabolism -MH - Male -MH - Muscle, Smooth, Vascular/metabolism/physiology -MH - Neovascularization, Physiologic/physiology -MH - Pre-Eclampsia/physiopathology/prevention & control -MH - Pregnancy -RF - 134 -EDAT- 2008/11/26 09:00 -MHDA- 2009/03/04 09:00 -CRDT- 2008/11/26 09:00 -PHST- 2008/11/26 09:00 [pubmed] -PHST- 2009/03/04 09:00 [medline] -PHST- 2008/11/26 09:00 [entrez] -AID - 5 [pii] -AID - 10.2165/00007256-200838120-00005 [doi] -PST - ppublish -SO - Sports Med. 2008;38(12):1009-24. doi: 10.2165/00007256-200838120-00005. - -PMID- 19800624 -OWN - NLM -STAT- MEDLINE -DCOM- 20100614 -LR - 20250529 -IS - 1879-1484 (Electronic) -IS - 0021-9150 (Print) -IS - 0021-9150 (Linking) -VI - 209 -IP - 2 -DP - 2010 Apr -TI - Combination therapy for treatment or prevention of atherosclerosis: focus on the - lipid-RAAS interaction. -PG - 307-13 -LID - 10.1016/j.atherosclerosis.2009.09.007 [doi] -AB - Large clinical trials demonstrate that control of blood pressure or - hyperlipidemia reduces risk for cardiovascular events by approximately 30%. - Factors that may further reduce remaining risk are not definitively established. - One potential target is atherosclerosis, a crucial feature in the pathogenesis of - cardiovascular diseases whose development is determined by multiple mechanism - including complex interactions between endothelial dysfunction and insulin - resistance. Reciprocal relationships between endothelial dysfunction and insulin - resistance as well as cross-talk between hyperlipidemia and the - rennin-angiotensin-aldosterone system may contribute to development of - atherosclerosis. Therefore, one appealing strategy for prevention or treatment of - atherosclerosis may be to simultaneously address several risk factors with - combination therapies that target multiple pathogenic mechanisms. Combination - therapy with statins, peroxisome proliferators-activated receptor agonists, and - rennin-angiotensin-aldosterone system blockers demonstrate additive beneficial - effects on endothelial dysfunction and insulin resistance when compared with - monotherapies in patients with cardiovascular risk factors. Additive beneficial - effects of combined therapy are mediated by both distinct and interrelated - mechanisms, consistent with both pre-clinical and clinical investigations. Thus, - combination therapy may be an important concept in developing more effective - strategies to treat and prevent atherosclerosis, coronary heart disease, and - co-morbid metabolic disorders characterized by endothelial dysfunction and - insulin resistance. -CI - Copyright 2009 Elsevier Ireland Ltd. All rights reserved. -FAU - Koh, Kwang Kon -AU - Koh KK -AD - Division of Cardiology, Gachon University, Gil Medical Center, Incheon, Republic - of Korea. kwangk@gilhospital.com -FAU - Han, Seung Hwan -AU - Han SH -FAU - Oh, Pyung Chun -AU - Oh PC -FAU - Shin, Eak Kyun -AU - Shin EK -FAU - Quon, Michael J -AU - Quon MJ -LA - eng -GR - Z01 AT000001/ImNIH/Intramural NIH HHS/United States -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090912 -PL - Ireland -TA - Atherosclerosis -JT - Atherosclerosis -JID - 0242543 -RN - 0 (Angiotensin Receptor Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Antihypertensive Agents) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Peroxisome Proliferator-Activated Receptors) -SB - IM -MH - Angiotensin Receptor Antagonists -MH - Angiotensin-Converting Enzyme Inhibitors/administration & dosage -MH - Animals -MH - Antihypertensive Agents/administration & dosage/therapeutic use -MH - Atherosclerosis/*drug therapy/physiopathology/*prevention & control -MH - Drug Therapy, Combination -MH - Endothelium/physiopathology -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & - dosage/therapeutic use -MH - Insulin Resistance -MH - Peroxisome Proliferator-Activated Receptors/physiology -MH - Renin-Angiotensin System/drug effects/*physiology -MH - Risk Factors -MH - Signal Transduction/drug effects -MH - Vascular Diseases/drug therapy/prevention & control -PMC - PMC2962413 -MID - NIHMS241079 -EDAT- 2009/10/06 06:00 -MHDA- 2010/06/15 06:00 -PMCR- 2010/10/22 -CRDT- 2009/10/06 06:00 -PHST- 2009/03/04 00:00 [received] -PHST- 2009/08/27 00:00 [revised] -PHST- 2009/09/04 00:00 [accepted] -PHST- 2009/10/06 06:00 [entrez] -PHST- 2009/10/06 06:00 [pubmed] -PHST- 2010/06/15 06:00 [medline] -PHST- 2010/10/22 00:00 [pmc-release] -AID - S0021-9150(09)00720-5 [pii] -AID - 10.1016/j.atherosclerosis.2009.09.007 [doi] -PST - ppublish -SO - Atherosclerosis. 2010 Apr;209(2):307-13. doi: - 10.1016/j.atherosclerosis.2009.09.007. Epub 2009 Sep 12. - -PMID- 19614796 -OWN - NLM -STAT- MEDLINE -DCOM- 20090924 -LR - 20211020 -IS - 1559-4572 (Electronic) -IS - 1559-4564 (Linking) -VI - 4 -IP - 2 -DP - 2009 Spring -TI - Utility of aspirin therapy in patients with the cardiometabolic syndrome and - diabetes. -PG - 96-101 -LID - 10.1111/j.1559-4572.2008.00037.x [doi] -AB - Paralleling the rise in obesity, the cardiometabolic syndrome is a rapidly - growing health problem in the United States. There is a 3-fold increase in the - prevalence of coronary heart disease, myocardial infarction, and stroke due to - the coagulation, hemodynamic, and metabolic abnormalities seen in these - individuals. The use of aspirin for secondary prevention and, to a lesser degree, - primary prevention of cardiovascular events is a well-established standard of - care. However, in patients with diabetes or the cardiometabolic syndrome, the - role of aspirin in prevention of cardiovascular events remains controversial. In - this review, the authors examine the clinical trial data on the use of aspirin in - diabetes and the cardiometabolic syndrome for cardiovascular protection. They - also explore, in addition to aspirin's effects on platelet aggregation, some of - the mechanisms by which aspirin may favorably alter the course of - atherosclerosis, effects on endothelial function, and glycemia. -FAU - Gardner, Michael -AU - Gardner M -AD - Diabetes and Cardiovascular Center, University of Missouri School of Medicine and - Truman VA Hospital, Columbia, MO 65212, USA. gardnermj@health.missouri.edu -FAU - Palmer, John -AU - Palmer J -FAU - Manrique, Camila -AU - Manrique C -FAU - Lastra, Guido -AU - Lastra G -FAU - Gardner, David W -AU - Gardner DW -FAU - Sowers, James R -AU - Sowers JR -LA - eng -GR - I01 BX001981/BX/BLRD VA/United States -GR - R01 HL073101/HL/NHLBI NIH HHS/United States -GR - R01 HL73101-01A1/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - United States -TA - J Cardiometab Syndr -JT - Journal of the cardiometabolic syndrome -JID - 101284690 -RN - 0 (Blood Glucose) -RN - 0 (Cardiovascular Agents) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Aspirin/*therapeutic use -MH - Blood Coagulation/drug effects -MH - Blood Glucose/metabolism -MH - Blood Platelets/drug effects -MH - Cardiovascular Agents/*therapeutic use -MH - Cardiovascular Diseases/blood/etiology/*prevention & control -MH - Diabetes Complications/blood/etiology/*prevention & control -MH - Diabetes Mellitus, Type 2/blood/complications/*drug therapy -MH - Endothelium, Vascular/drug effects -MH - Humans -MH - Metabolic Syndrome/blood/complications/*drug therapy -MH - Treatment Outcome -RF - 39 -EDAT- 2009/07/21 09:00 -MHDA- 2009/09/25 06:00 -CRDT- 2009/07/21 09:00 -PHST- 2009/07/21 09:00 [entrez] -PHST- 2009/07/21 09:00 [pubmed] -PHST- 2009/09/25 06:00 [medline] -AID - CMS037 [pii] -AID - 10.1111/j.1559-4572.2008.00037.x [doi] -PST - ppublish -SO - J Cardiometab Syndr. 2009 Spring;4(2):96-101. doi: - 10.1111/j.1559-4572.2008.00037.x. - -PMID- 17130644 -OWN - NLM -STAT- MEDLINE -DCOM- 20070525 -LR - 20220224 -IS - 0012-1797 (Print) -IS - 0012-1797 (Linking) -VI - 55 Suppl 2 -DP - 2006 Dec -TI - Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the - systemic response to exercise and prevention of the metabolic syndrome. -PG - S48-54 -AB - Interleukin (IL)-6 is a pleiotropic hormone that has both proinflammatory and - anti-inflammatory actions. AMP-activated protein kinase (AMPK) is a fuel-sensing - enzyme that among its other actions responds to decreases in cellular energy - state by enhancing processes that generate ATP and inhibiting others that consume - ATP but are not acutely necessary for survival. IL-6 is synthesized and released - from skeletal muscle in large amounts during exercise, and in rodents, the - resultant increase in its concentration correlates temporally with increases in - AMPK activity in multiple tissues. That IL-6 may be responsible in great measure - for these increases in AMPK is suggested by the fact it increases AMPK activity - both in muscle and adipose tissue in vivo and in incubated muscles and cultured - adipocytes. In addition, we have found that AMPK activity is diminished in muscle - and adipose tissue of 3-month-old IL-6 knockout (KO) mice at rest and that the - absolute increases in AMPK activity in these tissues caused by exercise is - diminished compared with control mice. Except for an impaired ability to exercise - and to oxidize fatty acids, the IL-6 KO mouse appears normal at 3 months of age. - On the other hand, by age 9 months, it manifests many of the abnormalities of the - metabolic syndrome including obesity, dyslipidemia, and impaired glucose - tolerance. This, plus the association of decreased AMPK activity with similar - abnormalities in a number of other rodents, suggests that a decrease in AMPK - activity may be a causal factor. Whether increases in IL-6, by virtue of their - effects on AMPK, contribute to the reported ability of exercise to diminish the - prevalence of type 2 diabetes, coronary heart disease, and other disorders - associated with the metabolic syndrome remains to be determined. -FAU - Ruderman, Neil B -AU - Ruderman NB -AD - Section of Endocrinology, Diabetes Unit, Boston Medical Center, 650 Albany St., - X-820, Boston, MA 02118, USA. -FAU - Keller, Charlotte -AU - Keller C -FAU - Richard, Ann-Marie -AU - Richard AM -FAU - Saha, Asish K -AU - Saha AK -FAU - Luo, Zhijun -AU - Luo Z -FAU - Xiang, Xiaoqin -AU - Xiang X -FAU - Giralt, Mercedes -AU - Giralt M -FAU - Ritov, Vladimir B -AU - Ritov VB -FAU - Menshikova, Elizabeth V -AU - Menshikova EV -FAU - Kelley, David E -AU - Kelley DE -FAU - Hidalgo, Juan -AU - Hidalgo J -FAU - Pedersen, Bente K -AU - Pedersen BK -FAU - Kelly, Meghan -AU - Kelly M -LA - eng -GR - DK049200/DK/NIDDK NIH HHS/United States -GR - DK07201/DK/NIDDK NIH HHS/United States -GR - DK19514/DK/NIDDK NIH HHS/United States -GR - P30-DK046204/DK/NIDDK NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Diabetes -JT - Diabetes.. -JID - 0372763 -RN - 0 (Interleukin-6) -RN - 0 (Multienzyme Complexes) -RN - EC 2.7.11.1 (Protein Serine-Threonine Kinases) -RN - EC 2.7.11.31 (AMP-Activated Protein Kinases) -SB - IM -MH - AMP-Activated Protein Kinases -MH - Adipose Tissue/physiology -MH - Animals -MH - Enzyme Activation/physiology -MH - Exercise/physiology -MH - Humans -MH - Interleukin-6/*physiology -MH - Metabolic Syndrome/physiopathology -MH - Mice -MH - Multienzyme Complexes/*physiology -MH - Muscle, Skeletal/physiology -MH - Protein Serine-Threonine Kinases/*physiology -RF - 58 -EDAT- 2006/11/30 09:00 -MHDA- 2007/05/26 09:00 -CRDT- 2006/11/30 09:00 -PHST- 2006/11/30 09:00 [pubmed] -PHST- 2007/05/26 09:00 [medline] -PHST- 2006/11/30 09:00 [entrez] -AID - 55/Supplement_2/S48 [pii] -AID - 10.2337/db06-s007 [doi] -PST - ppublish -SO - Diabetes. 2006 Dec;55 Suppl 2:S48-54. doi: 10.2337/db06-s007. - -PMID- 22132126 -OWN - NLM -STAT- MEDLINE -DCOM- 20120402 -LR - 20250626 -IS - 1932-6203 (Electronic) -IS - 1932-6203 (Linking) -VI - 6 -IP - 11 -DP - 2011 -TI - Prevalence of antidepressant prescription or use in patients with acute coronary - syndrome: a systematic review. -PG - e27671 -LID - 10.1371/journal.pone.0027671 [doi] -LID - e27671 -AB - BACKGROUND AND OBJECTIVES: Depression is common among acute coronary syndrome - (ACS) patients and is associated with poor prognosis. Cardiac side effects of - older antidepressants were well-known, but newer antidepressants are generally - thought of as safe to use in patients with heart disease. The objective was to - assess rates of antidepressant use or prescription to patients within a year of - an ACS. METHODS: PubMed, PsycINFO, and CINAHL databases searched through May 29, - 2009; manual searching of 33 journals from May 2009 to September 2010. Articles - in any language were included if they reported point or period prevalence of - antidepressant use or prescription in the 12 months prior or subsequent to an ACS - for ≥100 patients. Two investigators independently selected studies for - inclusion/exclusion and extracted methodological characteristics and outcomes - from included studies (study setting, inclusion/exclusion criteria, sample size, - prevalence of antidepressant prescription/use, method of assessing antidepressant - prescription/use, time period of assessment). RESULTS: A total of 24 articles - were included. The majority were from North America and Europe, and most utilized - chart review or self-report to assess antidepressant use or prescription. - Although there was substantial heterogeneity in results, overall, rates of - antidepressant use or prescription increased from less than 5% prior to 1995 to - 10-15% after 2000. In general, studies from North America reported substantially - higher rates than studies from Europe, approximately 5% higher among studies that - used chart or self-report data. CONCLUSIONS: Antidepressant use or prescription - has increased considerably, and by 2005 approximately 10% to 15% of ACS patients - were prescribed or using one of these drugs. -FAU - Czarny, Matthew J -AU - Czarny MJ -AD - Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, - United States of America. -FAU - Arthurs, Erin -AU - Arthurs E -FAU - Coffie, Diana-Frances -AU - Coffie DF -FAU - Smith, Cheri -AU - Smith C -FAU - Steele, Russell J -AU - Steele RJ -FAU - Ziegelstein, Roy C -AU - Ziegelstein RC -FAU - Thombs, Brett D -AU - Thombs BD -LA - eng -GR - R24 AT004641/AT/NCCIH NIH HHS/United States -GR - CAPMC/CIHR/Canada -GR - R24AT004641/AT/NCCIH NIH HHS/United States -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20111122 -PL - United States -TA - PLoS One -JT - PloS one -JID - 101285081 -RN - 0 (Antidepressive Agents) -SB - IM -MH - Acute Coronary Syndrome/*drug therapy/*epidemiology -MH - Aged -MH - Antidepressive Agents/*therapeutic use -MH - Databases as Topic -MH - Drug Prescriptions/*statistics & numerical data -MH - Female -MH - Humans -MH - Male -MH - Prevalence -PMC - PMC3222644 -COIS- Competing Interests: The authors have declared that no competing interests exist. -EDAT- 2011/12/02 06:00 -MHDA- 2012/04/03 06:00 -PMCR- 2011/11/22 -CRDT- 2011/12/02 06:00 -PHST- 2011/06/27 00:00 [received] -PHST- 2011/10/21 00:00 [accepted] -PHST- 2011/12/02 06:00 [entrez] -PHST- 2011/12/02 06:00 [pubmed] -PHST- 2012/04/03 06:00 [medline] -PHST- 2011/11/22 00:00 [pmc-release] -AID - PONE-D-11-11963 [pii] -AID - 10.1371/journal.pone.0027671 [doi] -PST - ppublish -SO - PLoS One. 2011;6(11):e27671. doi: 10.1371/journal.pone.0027671. Epub 2011 Nov 22. - -PMID- 16386823 -OWN - NLM -STAT- MEDLINE -DCOM- 20060510 -LR - 20161018 -IS - 0248-8663 (Print) -IS - 0248-8663 (Linking) -VI - 27 -IP - 3 -DP - 2006 Mar -TI - [Calcific arteriolopathy (Calciphylaxis)]. -PG - 184-95 -AB - PURPOSE: Calcific arteriolopathy (CA), also known as " Calciphylaxis " describes - a phenomenon of necrosis, mainly cutaneous and sometimes systemic, due to the - obliteration of the arteriole's lumen. Initially there are under-intimal calcium - deposits, and then the thrombosis occurs leading to the necrosis. CA affects - mainly the renal insufficient hemodialysed patient, but not exclusively. We - present 4 cases which illustrate well the etiologic spectrum of CA: terminal - renal insufficiency, neoplasia, primary hyperparathyroidism, proteinuria, vitamin - K inhibitors. We describe the AC's epidemiology, its cutaneous and systemic - clinical presentations, its treatment. We make the hypothesis that CA is a strong - risk marker in matter of cardiac mortality and we discuss this point. CURRENT - KNOWLEDGE AND KEY POINTS: In this article we describe the numerous breakthroughs - that have been made in matter of research about calcification over the past few - years: inhibitors of calcium phosphate deposition, vitamin D and PTH1R, - protein-calcium complexes, cell death, induction of bone formation. These data - are analysed from a clinical point of view with practical purposes. We present CA - not only as a cutaneous disease but as a systemic pathology. FUTURE PROSPECTS AND - PROJECTS: The CA epidemiology is an incentive to more diagnosis suspicion in - front of organ infarct involving a patient likely to be concerned by CA. The - scientific and therapeutic breakthroughs in matter of calcification enable a - better prevention of the disease. Nevertheless it remains very difficult to cure - when installed. -FAU - Duval, A -AU - Duval A -AD - Clinique dermatologique, Hôpital Claude-Huriez, CHRU, 59037 Lille, France. - arnaudduval@netcourrier.com -FAU - Moranne, O -AU - Moranne O -FAU - Vanhille, P -AU - Vanhille P -FAU - Hachulla, E -AU - Hachulla E -FAU - Delaporte, E -AU - Delaporte E -LA - fre -PT - Case Reports -PT - English Abstract -PT - Journal Article -PT - Review -TT - Artériolopathie calcique (Calciphylaxie). -DEP - 20051209 -PL - France -TA - Rev Med Interne -JT - La Revue de medecine interne -JID - 8101383 -RN - 0 (Phosphates) -RN - 12001-79-5 (Vitamin K) -RN - SY7Q814VUP (Calcium) -SB - IM -CIN - Rev Med Interne. 2006 Mar;27(3):181-3. doi: 10.1016/j.revmed.2005.11.003. PMID: - 16364506 -MH - Aged -MH - Arterioles/pathology -MH - Biopsy -MH - *Calciphylaxis/diagnosis/etiology/prevention & control/therapy -MH - Calcium/blood -MH - Coronary Artery Disease/prevention & control -MH - Fatal Outcome -MH - Female -MH - Humans -MH - Hyperparathyroidism/complications -MH - Kidney Failure, Chronic/complications -MH - Leg Ulcer/etiology/pathology -MH - Male -MH - Middle Aged -MH - Neoplasms/complications -MH - Phosphates/blood -MH - Proteinuria/complications -MH - Skin/blood supply/pathology -MH - Vitamin K/adverse effects/antagonists & inhibitors -RF - 76 -EDAT- 2006/01/03 09:00 -MHDA- 2006/05/11 09:00 -CRDT- 2006/01/03 09:00 -PHST- 2005/06/24 00:00 [received] -PHST- 2005/11/04 00:00 [revised] -PHST- 2005/11/07 00:00 [accepted] -PHST- 2006/01/03 09:00 [pubmed] -PHST- 2006/05/11 09:00 [medline] -PHST- 2006/01/03 09:00 [entrez] -AID - S0248-8663(05)00480-7 [pii] -AID - 10.1016/j.revmed.2005.11.001 [doi] -PST - ppublish -SO - Rev Med Interne. 2006 Mar;27(3):184-95. doi: 10.1016/j.revmed.2005.11.001. Epub - 2005 Dec 9. - -PMID- 24028171 -OWN - NLM -STAT- MEDLINE -DCOM- 20141124 -LR - 20211021 -IS - 1475-097X (Electronic) -IS - 1475-0961 (Print) -IS - 1475-0961 (Linking) -VI - 34 -IP - 3 -DP - 2014 May -TI - Review: comparison of PET rubidium-82 with conventional SPECT myocardial - perfusion imaging. -PG - 163-70 -LID - 10.1111/cpf.12083 [doi] -AB - Nuclear cardiology has for many years been focused on gamma camera technology. - With ever improving cameras and software applications, this modality has - developed into an important assessment tool for ischaemic heart disease. However, - the development of new perfusion tracers has been scarce. While cardiac positron - emission tomography (PET) so far largely has been limited to centres with on-site - cyclotron, recent developments with generator produced perfusion tracers such as - rubidium-82, as well as an increasing number of PET scanners installed, may - enable a larger patient flow that may supersede that of gamma camera myocardial - perfusion imaging. -CI - © 2013 The Authors. Clinical Physiology and Functional Imaging published by John - Wiley & Sons Ltd on behalf of the Scandinavian Society of Clinical Physiology and - Nuclear Medicine. -FAU - Ghotbi, Adam A -AU - Ghotbi AA -AD - Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for - Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. -FAU - Kjaer, Andreas -AU - Kjaer A -FAU - Hasbak, Philip -AU - Hasbak P -LA - eng -PT - Journal Article -PT - Review -DEP - 20130913 -PL - England -TA - Clin Physiol Funct Imaging -JT - Clinical physiology and functional imaging -JID - 101137604 -RN - 0 (Rubidium Radioisotopes) -SB - IM -MH - *Coronary Circulation -MH - Heart Diseases/*diagnostic imaging/physiopathology -MH - Humans -MH - Myocardial Perfusion Imaging/*methods -MH - *Positron-Emission Tomography -MH - Predictive Value of Tests -MH - *Rubidium Radioisotopes -MH - *Tomography, Emission-Computed, Single-Photon -PMC - PMC4204510 -OTO - NOTNLM -OT - cardiac PET -OT - cardiac SPECT -OT - cardiology -OT - myocardial perfusion imaging -OT - rubidium -EDAT- 2013/09/14 06:00 -MHDA- 2014/12/15 06:00 -CRDT- 2013/09/14 06:00 -PHST- 2013/04/11 00:00 [received] -PHST- 2013/08/14 00:00 [accepted] -PHST- 2013/09/14 06:00 [entrez] -PHST- 2013/09/14 06:00 [pubmed] -PHST- 2014/12/15 06:00 [medline] -AID - 10.1111/cpf.12083 [doi] -PST - ppublish -SO - Clin Physiol Funct Imaging. 2014 May;34(3):163-70. doi: 10.1111/cpf.12083. Epub - 2013 Sep 13. - -PMID- 23083773 -OWN - NLM -STAT- MEDLINE -DCOM- 20130129 -LR - 20220331 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 60 -IP - 20 -DP - 2012 Nov 13 -TI - Nonsustained ventricular tachycardia. -PG - 1993-2004 -LID - S0735-1097(12)04225-8 [pii] -LID - 10.1016/j.jacc.2011.12.063 [doi] -AB - Nonsustained ventricular tachycardia (NSVT) has been recorded in a wide range of - conditions, from apparently healthy individuals to patients with significant - heart disease. In the absence of heart disease, the prognostic significance of - NSVT is debatable. When detected during exercise, and especially at recovery, - NSVT indicates increased cardiovascular mortality within the next decades. In - trained athletes, NSVT is considered benign when suppressed by exercise. In - patients with non-ST-segment elevation acute coronary syndrome, NSVT occurring - beyond 48 h after admission indicates an increased risk of cardiac and sudden - death, especially when associated with myocardial ischemia. In acute myocardial - infarction, in-hospital NSVT has an adverse prognostic significance when detected - beyond the first 13 to 24 h. In patients with prior myocardial infarction treated - with reperfusion and beta-blockers, NSVT is not an independent predictor of - long-term mortality when other covariates such as left ventricular ejection - fraction are taken into account. In patients with hypertrophic cardiomyopathy, - and most probably genetic channelopathies, NSVT carries prognostic significance, - whereas its independent prognostic ability in ischemic heart failure and dilated - cardiomyopathy has not been established. The management of patients with NSVT is - aimed at treating the underlying heart disease. -CI - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Katritsis, Demosthenes G -AU - Katritsis DG -AD - Athens Euroclinic, Athens, Greece. dkatritsis@euroclinic.gr -FAU - Zareba, Wojciech -AU - Zareba W -FAU - Camm, A John -AU - Camm AJ -LA - eng -PT - Journal Article -PT - Review -DEP - 20121017 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Cardiomyopathy, Hypertrophic/*complications -MH - Death, Sudden, Cardiac/etiology -MH - Humans -MH - Myocardial Ischemia/*complications -MH - Prognosis -MH - Risk Factors -MH - *Tachycardia, Ventricular/diagnosis/etiology/therapy -EDAT- 2012/10/23 06:00 -MHDA- 2013/01/30 06:00 -CRDT- 2012/10/23 06:00 -PHST- 2011/11/06 00:00 [received] -PHST- 2011/12/08 00:00 [revised] -PHST- 2011/12/20 00:00 [accepted] -PHST- 2012/10/23 06:00 [entrez] -PHST- 2012/10/23 06:00 [pubmed] -PHST- 2013/01/30 06:00 [medline] -AID - S0735-1097(12)04225-8 [pii] -AID - 10.1016/j.jacc.2011.12.063 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2012 Nov 13;60(20):1993-2004. doi: 10.1016/j.jacc.2011.12.063. - Epub 2012 Oct 17. - -PMID- 22840347 -OWN - NLM -STAT- MEDLINE -DCOM- 20130415 -LR - 20131121 -IS - 1879-1913 (Electronic) -IS - 0002-9149 (Linking) -VI - 110 -IP - 9 -DP - 2012 Nov 1 -TI - Meta-analysis of safety of the coadministration of statin with fenofibrate in - patients with combined hyperlipidemia. -PG - 1296-301 -LID - S0002-9149(12)01704-3 [pii] -LID - 10.1016/j.amjcard.2012.06.050 [doi] -AB - Addition of fenofibrate to statin therapy might represent a viable treatment - option for patients whose high risk for coronary heart disease is not controlled - by a statin alone. However, safety of coadministration of statin with fenofibrate - has been a great concern. The present study tested the safety of coadministration - of statin with fenofibrate. We systematically searched the literature to identify - randomized controlled trials examining safety of coadministration of statin with - fenofibrate. A meta-analysis was performed to estimate safety of coadministration - of statin with fenofibrate using fixed-effects models. There were 1,628 subjects - in the identified 6 studies. Discontinuation attributed to any adverse events - (4.5% vs 3.1%, p = 0.20), any adverse events (42% vs 41%, p = 0.82), adverse - events related to study drug (10.9% vs 11.0%, p = 0.95), and serious adverse - events (2.0% vs 1.5%, p = 0.71) were not significantly different in the 2 arms. - Incidence of alanine aminotransferase and/or aspartate aminotransferase ≥3 times - upper limit of normal in the combination therapy arm was significantly higher - than in the statin monotherapy arm (3.1% vs 0.2%, p = 0.0009). In the 6 trials - with 1,628 subjects no case of myopathy or rhabdomyolysis was reported. In - conclusion, statin-fenofibrate combination therapy was tolerated as well as - statin monotherapy. Physicians should consider statin-fenofibrate combination - therapy to treat patients with mixed dyslipidemia. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Guo, Jinrui -AU - Guo J -AD - Department of Cardiology, Affiliated Hospital of Chengde Medical College, - Chengde, Hebei China. -FAU - Meng, Fanbo -AU - Meng F -FAU - Ma, Ning -AU - Ma N -FAU - Li, Chunhua -AU - Li C -FAU - Ding, Zhenjiang -AU - Ding Z -FAU - Wang, Hong -AU - Wang H -FAU - Hou, Ruitian -AU - Hou R -FAU - Qin, Yingjie -AU - Qin Y -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Meta-Analysis -PT - Review -DEP - 20120727 -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Hypolipidemic Agents) -RN - U202363UOS (Fenofibrate) -SB - IM -MH - Age Factors -MH - Aged -MH - Cross-Over Studies -MH - Dose-Response Relationship, Drug -MH - Drug Administration Schedule -MH - Drug Therapy, Combination/adverse effects -MH - Female -MH - Fenofibrate/*administration & dosage/adverse effects -MH - Follow-Up Studies -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage/adverse - effects -MH - Hyperlipidemia, Familial Combined/diagnosis/*drug therapy/mortality -MH - Hypolipidemic Agents/*administration & dosage/adverse effects -MH - Male -MH - Middle Aged -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - Safety Management -MH - Severity of Illness Index -MH - Sex Factors -MH - Survival Rate -MH - Treatment Outcome -EDAT- 2012/07/31 06:00 -MHDA- 2013/04/16 06:00 -CRDT- 2012/07/31 06:00 -PHST- 2012/04/29 00:00 [received] -PHST- 2012/06/08 00:00 [revised] -PHST- 2012/06/08 00:00 [accepted] -PHST- 2012/07/31 06:00 [entrez] -PHST- 2012/07/31 06:00 [pubmed] -PHST- 2013/04/16 06:00 [medline] -AID - S0002-9149(12)01704-3 [pii] -AID - 10.1016/j.amjcard.2012.06.050 [doi] -PST - ppublish -SO - Am J Cardiol. 2012 Nov 1;110(9):1296-301. doi: 10.1016/j.amjcard.2012.06.050. - Epub 2012 Jul 27. - -PMID- 18312905 -OWN - NLM -STAT- MEDLINE -DCOM- 20080415 -LR - 20131121 -IS - 0733-8651 (Print) -IS - 0733-8651 (Linking) -VI - 26 -IP - 1 -DP - 2008 Feb -TI - Anticoagulants, antiplatelets, and statins in heart failure. -PG - 49-58, vi -LID - 10.1016/j.ccl.2007.10.001 [doi] -AB - The existing guidelines for the treatment of patients who have heart failure - limit the administration of antiplatelet and anticoagulant agents to patients who - have specific comorbidities, including coronary artery disease, atrial - fibrillation, history of thromboembolic events, and left ventricular mural - thrombus. Retrospective analyses of large clinical trials or smaller - nonrandomized studies indicate that the use of statins may be beneficial both in - ischemic and idiopathic dilated cardiomyopathy. This article outlines the current - knowledge regarding the use of antiplatelet and anticoagulant agents and statins - in patients who have heart failure. -FAU - Farmakis, Dimitrios -AU - Farmakis D -AD - University of Athens Medical School, Attikon University Hospital, Athens, Greece. -FAU - Filippatos, Gerasimos -AU - Filippatos G -FAU - Lainscak, Mitja -AU - Lainscak M -FAU - Parissis, John T -AU - Parissis JT -FAU - Anker, Stefan D -AU - Anker SD -FAU - Kremastinos, Dimitrios T -AU - Kremastinos DT -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -RN - 0 (Anticoagulants) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 5Q7ZVV76EI (Warfarin) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Anticoagulants/*administration & dosage -MH - Aspirin/administration & dosage -MH - Drug Administration Schedule -MH - Heart Failure/*drug therapy -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage -MH - Platelet Aggregation Inhibitors/*administration & dosage -MH - Warfarin/administration & dosage -RF - 53 -EDAT- 2008/03/04 09:00 -MHDA- 2008/04/16 09:00 -CRDT- 2008/03/04 09:00 -PHST- 2008/03/04 09:00 [pubmed] -PHST- 2008/04/16 09:00 [medline] -PHST- 2008/03/04 09:00 [entrez] -AID - S0733-8651(07)00114-2 [pii] -AID - 10.1016/j.ccl.2007.10.001 [doi] -PST - ppublish -SO - Cardiol Clin. 2008 Feb;26(1):49-58, vi. doi: 10.1016/j.ccl.2007.10.001. - -PMID- 20456733 -OWN - NLM -STAT- MEDLINE -DCOM- 20100813 -LR - 20250626 -IS - 1365-2710 (Electronic) -IS - 0269-4727 (Linking) -VI - 35 -IP - 2 -DP - 2010 Apr -TI - A systematic review and meta-analysis on the therapeutic equivalence of statins. -PG - 139-51 -LID - 10.1111/j.1365-2710.2009.01085.x [doi] -AB - BACKGROUND: Statins are the most commonly prescribed agents for - hypercholesterolemia because of their efficacy and tolerability. As the number of - patients in need of statin therapy continues to increase, information regarding - the relative efficacy and safety of statins is required for decision-making. - OBJECTIVE: This study will use systematic review to compare the efficacy and - safety profiles of different statins at different doses and determine the - therapeutically equivalent doses of statins to achieve a specific level of - low-density lipoprotein cholesterol (LDL-C) lowering effect. METHODS: - Publications of head-to-head randomized controlled trials (RCTs) of statins were - retrieved from the Oregon state database (1966-2004), MEDLINE (2005-April of - 2006), EMBASE (2005-April of 2006), and the Cochrane Controlled Trials Registry - (up to the first quarter of 2006). The publications were evaluated with - predetermined criteria by a reviewer before they were included in the review. The - mean change in cholesterol level of each statin was calculated and weighted by - number of subjects involved in each RCT. Where possible, meta-analysis was - performed to generate pooled estimates of the cholesterol lowering effect of - statins and the difference between statins. RESULTS: Seventy-five studies - reporting RCTs of head-to-head comparisons on statins were included. Most studies - had similar baseline characteristics, except the rosuvastatin related studies. A - daily dose of atorvastatin 10 mg, fluvastatin 80 mg, lovastatin 40-80 mg, and - simvastatin 20 mg could decrease LDL-C by 30-40%, and fluvastatin 40 mg, - lovastatin 10-20 mg, pravastatin 20-40 mg, and simvastatin 10 mg could decrease - LDL-C by 20-30%. The only two statins that could reduce LDL-C more than 40% were - rosuvastatin and atorvastatin at a daily dose of 20 mg or higher. Meta-analysis - indicated a statistically significant but clinically minor difference (<7%) - between statins in cholesterol lowering effect. Comparisons of coronary heart - disease prevention and safety could not be made because of insufficient data. - CONCLUSIONS: At comparable doses, statins are therapeutically equivalent in - reducing LDL-C. -FAU - Weng, T-C -AU - Weng TC -AD - Institute of Clinical Pharmacy, College of Medicine, National Cheng Kung - University, Tainan, Taiwan. -FAU - Yang, Y-H Kao -AU - Yang YH -FAU - Lin, S-J -AU - Lin SJ -FAU - Tai, S-H -AU - Tai SH -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -PL - England -TA - J Clin Pharm Ther -JT - Journal of clinical pharmacy and therapeutics -JID - 8704308 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Anticholesteremic Agents/adverse effects/*pharmacokinetics/therapeutic use -MH - Cholesterol, LDL/drug effects -MH - Dose-Response Relationship, Drug -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse - effects/*pharmacokinetics/therapeutic use -MH - Hypercholesterolemia/*drug therapy -MH - Randomized Controlled Trials as Topic -MH - Therapeutic Equivalency -RF - 20 -EDAT- 2010/05/12 06:00 -MHDA- 2010/08/14 06:00 -CRDT- 2010/05/12 06:00 -PHST- 2010/05/12 06:00 [entrez] -PHST- 2010/05/12 06:00 [pubmed] -PHST- 2010/08/14 06:00 [medline] -AID - JCP1085 [pii] -AID - 10.1111/j.1365-2710.2009.01085.x [doi] -PST - ppublish -SO - J Clin Pharm Ther. 2010 Apr;35(2):139-51. doi: 10.1111/j.1365-2710.2009.01085.x. - -PMID- 21938821 -STAT- Publisher -CTDT- 20100709 -PB - Agency for Healthcare Research and Quality (US) -CTI - AHRQ Comparative Effectiveness Reviews -DP - 2007 -TI - Adding ACEIs and/or ARBs to Standard Therapy for Stable Ischemic Heart Disease: - Benefits and Harms. -BTI - Comparative Effectiveness Review Summary Guides for Clinicians -AB - Should standard medical therapy in patients with stable ischemic heart disease be - augmented with an ACEI (angiotensin-converting enzyme inhibitor) or an ARB - (angiotensin II receptor blocker)? Patients who have chronic stable angina, or - stable ischemic heart disease (IHD) with preserved left ventricular systolic - function (LVSF), can remain symptomatic and at risk for fatal and nonfatal - cardiovascular events, even though they may be optimally treated with standard - medical therapy or revascularization. Standard medical treatment may include - aspirin, statins, β-blockers, dual antiplatelet therapy, or combinations of these - agents. Nitrates and calcium channel blockers may also be used to achieve - symptomatic relief. Revascularization procedures can include balloon angioplasty - with or without stenting to open up the affected vessels of the heart or coronary - artery bypass grafting that attempts to bypass a diseased vessel. ACEIs and ARBs - have been shown to reduce morbidity and mortality in patients with left - ventricular systolic dysfunction (LVSD) in the settings of chronic heart failure - and myocardial infarction and also in patients with diabetes mellitus that is - accompanied by proteinuria or chronic kidney disease. This summary does not - discuss ACEI or ARB therapy for patients with currently accepted indications for - these drugs, including LVSD, evidence or diagnosis of heart failure, or a - diagnosis of cardiomyopathy. This summary presents the benefits and risks of - supplementing standard medical therapy with ACEIs or ARBs to patients with stable - IHD and preserved LVSF. It is based on a systematic review of the research - conducted for this population, which included 12 trials (n=41,672). -CN - John M. Eisenberg Center for Clinical Decisions and Communications Science -AD - Baylor College of Medicine, Houston, Texas -LA - eng -PT - Review -PT - Book Chapter -PL - Rockville (MD) -EDAT- 2010/07/09 00:00 -CRDT- 2010/07/09 00:00 -AID - NBK47075 [bookaccession] - -PMID- 19695355 -OWN - NLM -STAT- MEDLINE -DCOM- 20090915 -LR - 20220317 -IS - 1879-1913 (Electronic) -IS - 0002-9149 (Linking) -VI - 104 -IP - 5 Suppl -DP - 2009 Sep 7 -TI - Predictors and impact of bleeding complications in percutaneous coronary - intervention, acute coronary syndromes, and ST-segment elevation myocardial - infarction. -PG - 9C-15C -LID - 10.1016/j.amjcard.2009.06.020 [doi] -AB - Although the use of oral and intravenous antiplatelet and antithrombin therapy in - the acute and chronic settings of percutaneous coronary intervention (PCI), acute - coronary syndromes (ACS), and ST-segment elevation myocardial infarction (STEMI) - effectively reduce ischemic event rates, they are mechanistically and - inextricably linked to an increased risk of bleeding. As longer courses of more - complex, potent regimens are used, increased efficacy may be offset by increases - in major, minor, and nuisance bleeding, both in the inpatient and outpatient - setting. Consequently, more frequent challenges with cessation of and compliance - with antithrombotic therapy are to be expected. Extensive data indicate that - bleeding complications (1) occur with relative frequency; (2) independently - affect adverse outcomes, such as mortality; (3) carry similar importance in - adversely influencing mortality as ischemic events; (4) can be predicted by - recognizing patient, presentation, treatment, and procedural risk factors for - bleeding; and (5) can be modified by pharmacologic and nonpharmacologic means. - Factors associated with increased bleeding risk include: (1) patient - characteristics (including advanced age, female sex, hypertension, renal disease, - anemia, previous history of bleeding, and perhaps diabetes mellitus), (2) - clinical presentation (bleeding rates appears lowest for PCI, higher for ACS, and - highest for STEMI), (3) abnormalities of cardiac biomarkers and/or - electrocardiography, (4) invasive procedures (such as cardiac catheterization and - PCI), and (5) the choice of antiplatelet and antithrombin therapy. In the context - of a bleeding assessment, evidence-based decision making should always result in - the selection of appropriate pharmacologic and nonpharmacologic strategies, - invasive or conservative management plans, and stent types (bare metal vs - drug-eluting) that will offer the best balance of benefit and risk with the goal - of optimizing outcomes. -FAU - Manoukian, Steven V -AU - Manoukian SV -AD - Sarah Cannon Research Institute, Clinical Services Group, Hospital Corporation of - America (HCA), Inc., and Centennial Heart Cardiovascular Consultants, 3322 West - End Avenue, Nashville, TN 37203, USA. steven.manoukian@hcahealthcare.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -RN - 0 (Fibrinolytic Agents) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Acute Coronary Syndrome/complications/mortality/*therapy -MH - Angioplasty, Balloon, Coronary/*adverse effects -MH - Fibrinolytic Agents/therapeutic use -MH - Humans -MH - Myocardial Infarction/complications/mortality/*therapy -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Postoperative Hemorrhage/*epidemiology -MH - Risk Factors -RF - 17 -EDAT- 2009/08/27 09:00 -MHDA- 2009/09/16 06:00 -CRDT- 2009/08/22 09:00 -PHST- 2009/08/22 09:00 [entrez] -PHST- 2009/08/27 09:00 [pubmed] -PHST- 2009/09/16 06:00 [medline] -AID - S0002-9149(09)01236-3 [pii] -AID - 10.1016/j.amjcard.2009.06.020 [doi] -PST - ppublish -SO - Am J Cardiol. 2009 Sep 7;104(5 Suppl):9C-15C. doi: 10.1016/j.amjcard.2009.06.020. - -PMID- 23610137 -OWN - NLM -STAT- MEDLINE -DCOM- 20131219 -LR - 20220330 -IS - 1879-0844 (Electronic) -IS - 1388-9842 (Linking) -VI - 15 -IP - 6 -DP - 2013 Jun -TI - How do patients with heart failure with preserved ejection fraction die? -PG - 604-13 -LID - 10.1093/eurjhf/hft062 [doi] -AB - Understanding how patients with heart failure with preserved ejection fraction - (HFPEF) die provides insight into the natural history and pathophysiology of this - complex syndrome, thereby allowing better prediction of response to therapy in - designing clinical trials. This review summarizes the current state of knowledge - surrounding mortality rates, modes of death, and prognostic factors in HFPEF. - Despite the lack of uniform reporting, the following conclusions may be drawn - from previous studies. The mortality burden of HFPEF is substantial, ranging from - 10% to 30% annually, and higher in epidemiological studies than in clinical - trials. Mortality rates compared with heart failure with reduced ejection - fraction (HFREF) appear to be strongly influenced by the type of study, but are - clearly elevated compared with age- and co-morbidity-matched controls without - heart failure. The majority of deaths in HFPEF are cardiovascular deaths, - comprising 51-60% of deaths in epidemiological studies and ∼70% in clinical - trials. Among cardiovascular deaths, sudden death and heart failure death are the - leading cardiac modes of death in HFPEF clinical trials. Compared with HFREF, the - proportions of cardiovascular deaths, sudden death, and heart failure deaths are - lower in HFPEF. Conversely, non-cardiovascular deaths constitute a higher - proportion of deaths in HFPEF than in HFREF, particularly in epidemiological - studies, where this difference may be related to fewer coronary heart deaths in - HFPEF. Key mortality risk factors, including age, gender, body mass index, burden - of co-morbidities, and coronary artery disease, offer some explanation for the - differences in mortality rates observed across studies. -FAU - Chan, Michelle M Y -AU - Chan MM -AD - Cardiovascular Research Institute, National University of Singapore, Singapore. -FAU - Lam, Carolyn S P -AU - Lam CS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130421 -PL - England -TA - Eur J Heart Fail -JT - European journal of heart failure -JID - 100887595 -SB - IM -MH - Cause of Death -MH - Heart Failure/*mortality/*physiopathology -MH - Humans -MH - Prognosis -MH - Risk Factors -MH - Stroke Volume/*physiology -OTO - NOTNLM -OT - Clinical trial -OT - Epidemiology -OT - Heart failure with preserved ejection fraction -OT - Mortality -OT - Outcomes -EDAT- 2013/04/24 06:00 -MHDA- 2013/12/20 06:00 -CRDT- 2013/04/24 06:00 -PHST- 2013/04/24 06:00 [entrez] -PHST- 2013/04/24 06:00 [pubmed] -PHST- 2013/12/20 06:00 [medline] -AID - hft062 [pii] -AID - 10.1093/eurjhf/hft062 [doi] -PST - ppublish -SO - Eur J Heart Fail. 2013 Jun;15(6):604-13. doi: 10.1093/eurjhf/hft062. Epub 2013 - Apr 21. - -PMID- 16937031 -OWN - NLM -STAT- MEDLINE -DCOM- 20061207 -LR - 20220331 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 11 -IP - 2 -DP - 2006 Jun -TI - Diagnostic and imaging considerations: role of viability. -PG - 125-34 -AB - Left ventricular systolic dysfunction is a recognised feature of heart failure. - In developed nations, the leading cause of left ventricular systolic dysfunction - is coronary artery disease. Revascularisation is a treatment strategy for - patients with predominant symptoms of heart failure and significant left - ventricular dysfunction. Presence or absence of myocardial viability has been - shown to affect outcome after revascularisation. There are various techniques to - assess myocardial viability. However, limitations of current literature, lack of - completed randomised trials and high peri-procedural trials create significant - uncertainty about the optimal strategy. This review focuses on the role of - non-invasive testing for myocardial viability in patients with left ventricular - systolic dysfunction and heart failure and also outlines the pros and cons of - each technique. -FAU - Senior, Roxy -AU - Senior R -AD - Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Road, - Harrow Middlesex, HA1 3UJ, United Kingdom. roxy.senior@virgin.net -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -SB - IM -MH - Diagnostic Imaging/methods -MH - Echocardiography, Stress -MH - Heart Failure/*diagnosis/diagnostic imaging/mortality/pathology/surgery -MH - Humans -MH - Magnetic Resonance Imaging -MH - Myocardial Revascularization -MH - Myocardium/*pathology -MH - Positron-Emission Tomography -MH - Tomography, Emission-Computed, Single-Photon -RF - 94 -EDAT- 2006/08/29 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/08/29 09:00 -PHST- 2006/08/29 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/08/29 09:00 [entrez] -AID - 10.1007/s10741-006-9483-y [doi] -PST - ppublish -SO - Heart Fail Rev. 2006 Jun;11(2):125-34. doi: 10.1007/s10741-006-9483-y. - -PMID- 24462011 -OWN - NLM -STAT- MEDLINE -DCOM- 20140321 -LR - 20151119 -IS - 1555-7162 (Electronic) -IS - 0002-9343 (Linking) -VI - 127 -IP - 2 -DP - 2014 Feb -TI - Diagnostic and therapeutic implications of type 2 myocardial infarction: review - and commentary. -PG - 105-8 -LID - S0002-9343(13)00880-2 [pii] -LID - 10.1016/j.amjmed.2013.09.031 [doi] -AB - The Task Force for the Universal Definition of Myocardial Infarction recently - published updated guidelines for the clinical and research diagnosis of - myocardial infarction under a variety of circumstances and in a variety of - categories. A type 1 myocardial infarction (MI) is usually the result of - atherosclerotic coronary artery disease with thrombotic coronary arterial - obstruction secondary to atherosclerotic plaque rupture, ulceration, fissuring, - or dissection, causing coronary arterial obstruction with resultant myocardial - ischemia and necrosis. Patients with a type 2 MI do not have atherosclerotic - plaque rupture. In this latter group of patients, myocardial necrosis occurs - because of an increase in myocardial oxygen demand or a decrease in myocardial - blood flow. Type 2 MI has been the subject of considerable clinical discussion - and confusion. This review by knowledgeable members of the Task Force seeks to - help clinicians resolve the confusion surrounding type 2 MI. -CI - Copyright © 2014 Elsevier Inc. All rights reserved. -FAU - Alpert, Joseph S -AU - Alpert JS -AD - Sarver Heart Center, University of Arizona College of Medicine, Tucson. - Electronic address: jalpert@shc.arizona.edu. -FAU - Thygesen, Kristian A -AU - Thygesen KA -AD - Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark. -FAU - White, Harvey D -AU - White HD -AD - Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand. -FAU - Jaffe, Allan S -AU - Jaffe AS -AD - Mayo Clinic, Rochester, Minn. -LA - eng -PT - Journal Article -PT - Review -DEP - 20131016 -PL - United States -TA - Am J Med -JT - The American journal of medicine -JID - 0267200 -RN - 0 (Biomarkers) -RN - 0 (Troponin) -SB - IM -MH - Biomarkers/blood -MH - Blood Pressure -MH - *Coronary Circulation -MH - Electrocardiography -MH - Humans -MH - Myocardial Infarction/blood/*diagnosis/metabolism/physiopathology/*therapy -MH - Myocardium/*metabolism/*pathology -MH - Necrosis -MH - *Oxygen Consumption -MH - Troponin/blood -OTO - NOTNLM -OT - Clinical definition -OT - Myocardial infarction -OT - Troponin -EDAT- 2014/01/28 06:00 -MHDA- 2014/03/22 06:00 -CRDT- 2014/01/28 06:00 -PHST- 2013/09/16 00:00 [received] -PHST- 2013/09/24 00:00 [accepted] -PHST- 2014/01/28 06:00 [entrez] -PHST- 2014/01/28 06:00 [pubmed] -PHST- 2014/03/22 06:00 [medline] -AID - S0002-9343(13)00880-2 [pii] -AID - 10.1016/j.amjmed.2013.09.031 [doi] -PST - ppublish -SO - Am J Med. 2014 Feb;127(2):105-8. doi: 10.1016/j.amjmed.2013.09.031. Epub 2013 Oct - 16. - -PMID- 19917800 -OWN - NLM -STAT- MEDLINE -DCOM- 20100126 -LR - 20091117 -IS - 1816-5370 (Electronic) -IS - 0218-4923 (Linking) -VI - 17 -IP - 5 -DP - 2009 Oct -TI - The forgotten driving forces in right heart failure: new concept and device. -PG - 525-30 -LID - 10.1177/0218492309348638 [doi] -AB - BACKGROUND: Right heart failure is a frequent hemodynamic disturbance in - pediatric cardiac patients. Besides inotropic and chronotropic drugs, fluid - administration and inhaled nitric oxide, right ventricular mechanical assistance - remains difficult to perform. A circulatory assist device adapted for the right - heart biophysics and physiology might be more efficient. MATERIALS AND METHODS: - We are developing a prototype of a non-invasive cardiac assist device (CAD) for - neonates and pediatrics. It is based on a pulsatile suit device covering and - affecting all territories of the right heart circuit. It will be tested in a - neonatal animal model of right ventricular (RV) failure. Experimental models will - be matched and compared with control and sham groups. Expected results would be - immediate hemodynamic improvement due to synchronized diastolic reduction of - stagnant venous capacitance, increasing preload and contractility. On long term, - increased shear stress with changing intrathoracic pressure in a phasic way would - improve and remodel the pulmonary circulation. Future studies will be focused on: - hemodynamic, biochemistry, endothelium function test, and angiogenesis. COMMENTS: - A non-invasive CAD guarantees better hemodynamics and endothelial function - preservation with low morbidity and mortality. This is a physiological approach, - cost-effective method, and particularly interesting in neonates and pediatrics - with RV failure. -FAU - Nour, Sayed -AU - Nour S -AD - Laboratory of Biosurgical Research, 96 rue Didot, 75014 Paris, France. - nourmd@mac.com -FAU - Wu, Guifu -AU - Wu G -FAU - Zhensheng, Zheng -AU - Zhensheng Z -FAU - Chachques, Juan C -AU - Chachques JC -FAU - Carpentier, Alain -AU - Carpentier A -FAU - Payen, Didier -AU - Payen D -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Asian Cardiovasc Thorac Ann -JT - Asian cardiovascular & thoracic annals -JID - 9503417 -SB - IM -MH - Animals -MH - Coronary Circulation -MH - Disease Models, Animal -MH - Equipment Design -MH - Heart Failure/physiopathology/*therapy -MH - *Heart-Assist Devices/adverse effects -MH - *Hemodynamics -MH - Humans -MH - Infant -MH - Infant, Newborn -MH - Myocardial Contraction -MH - Pulmonary Circulation -MH - Pulsatile Flow -MH - *Ventricular Function, Right -RF - 21 -EDAT- 2009/11/18 06:00 -MHDA- 2010/01/27 06:00 -CRDT- 2009/11/18 06:00 -PHST- 2009/11/18 06:00 [entrez] -PHST- 2009/11/18 06:00 [pubmed] -PHST- 2010/01/27 06:00 [medline] -AID - 17/5/525 [pii] -AID - 10.1177/0218492309348638 [doi] -PST - ppublish -SO - Asian Cardiovasc Thorac Ann. 2009 Oct;17(5):525-30. doi: - 10.1177/0218492309348638. - -PMID- 20109418 -OWN - NLM -STAT- MEDLINE -DCOM- 20100513 -LR - 20190917 -IS - 1579-2242 (Electronic) -IS - 0300-8932 (Linking) -VI - 63 -IP - 2 -DP - 2010 Feb -TI - Imaging techniques and the evaluation of the right heart and the pulmonary - circulation. -PG - 209-23 -AB - Since the right side of the heart and the pulmonary circulation are regarded as - secondary components of the circulatory system, their role in disease has - traditionally not received the same attention as their counterparts in the - systemic circulation. This was partly because precise noninvasive study of these - structures was difficult. For many years, chest radiography and invasive - angiography were the only techniques available for imaging the minor circulation. - The development of transthoracic echocardiography and nuclear techniques has - produced a significant leap forward for noninvasive imaging, particularly of the - right ventricle. More recently, novel echocardiographic techniques, and advances - in computed tomography and magnetic resonance imaging, in particular, have - expanded our diagnostic armamentarium and provided new insights into the anatomy - and function of the pulmonary circulation in both health and disease. This - article contains a review of the current status of techniques for imaging the - right side of the heart and the pulmonary circulation. -FAU - Sanz, Javier -AU - Sanz J -AD - The Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josee and Henry - R. Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New - York, NY, USA. Javier.Sanz@mssm.edu -FAU - Fernández-Friera, Leticia -AU - Fernández-Friera L -FAU - Moral, Sergio -AU - Moral S -LA - eng -LA - spa -PT - Journal Article -PT - Review -PL - Spain -TA - Rev Esp Cardiol -JT - Revista espanola de cardiologia -JID - 0404277 -SB - IM -MH - Coronary Angiography -MH - Echocardiography -MH - Heart/*diagnostic imaging -MH - Humans -MH - Magnetic Resonance Imaging -MH - Pulmonary Circulation/*physiology -MH - Radiography, Thoracic -MH - Radionuclide Imaging -MH - Tomography, X-Ray Computed -RF - 96 -EDAT- 2010/01/30 06:00 -MHDA- 2010/05/14 06:00 -CRDT- 2010/01/30 06:00 -PHST- 2010/01/30 06:00 [entrez] -PHST- 2010/01/30 06:00 [pubmed] -PHST- 2010/05/14 06:00 [medline] -AID - S0300-8932(10)70039-7 [pii] -AID - 10.1016/s1885-5857(10)70039-6 [doi] -PST - ppublish -SO - Rev Esp Cardiol. 2010 Feb;63(2):209-23. doi: 10.1016/s1885-5857(10)70039-6. - -PMID- 18324359 -OWN - NLM -STAT- MEDLINE -DCOM- 20080814 -LR - 20211020 -IS - 1828-0447 (Print) -IS - 1828-0447 (Linking) -VI - 3 -IP - 1 -DP - 2008 Mar -TI - Troponin I in the intensive care unit setting: from the heart to the heart. -PG - 9-16 -LID - 10.1007/s11739-008-0089-3 [doi] -AB - When measured in the plasma, cardiac troponins T (cTnT) and I (cTnI) are - considered to be highly specific markers of myocardial cell damage; however, - research has demonstrated that troponin elevation may associated with causes - other than coronary artery disease. In the intensive care unit (ICU) setting, - increased cTnI levels are quite common findings and when documented, even on - admission, intensivists should bear in mind that this laboratory finding holds a - prognostic role independent of the reason for ICU admission. The mechanism(s) - (such as demand ischemia, myocardial strain, etc.) and not simply the cause - (i.e., renal failure) of the increment in serum cTnI should be investigated to - better tailor the therapeutical regimen in the single patient. In this review, we - therefore consider the nonthrombotic causes of troponin elevation in the critical - setting. -FAU - Lazzeri, Chiara -AU - Lazzeri C -AD - Intensive Cardiac Care Unit, Heart and Vessel Department, Azienda - Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy. -FAU - Bonizzoli, Manuela -AU - Bonizzoli M -FAU - Cianchi, Giovanni -AU - Cianchi G -FAU - Gensini, Gian Franco -AU - Gensini GF -FAU - Peris, Adriano -AU - Peris A -LA - eng -PT - Journal Article -PT - Review -DEP - 20080307 -PL - Italy -TA - Intern Emerg Med -JT - Internal and emergency medicine -JID - 101263418 -RN - 0 (Biomarkers) -RN - 0 (Troponin I) -SB - IM -MH - Biomarkers -MH - *Diagnosis, Differential -MH - Humans -MH - *Intensive Care Units -MH - Sepsis -MH - Troponin I/*blood -RF - 63 -EDAT- 2008/03/08 09:00 -MHDA- 2008/08/15 09:00 -CRDT- 2008/03/08 09:00 -PHST- 2006/10/23 00:00 [received] -PHST- 2007/04/02 00:00 [accepted] -PHST- 2008/03/08 09:00 [pubmed] -PHST- 2008/08/15 09:00 [medline] -PHST- 2008/03/08 09:00 [entrez] -AID - 10.1007/s11739-008-0089-3 [doi] -PST - ppublish -SO - Intern Emerg Med. 2008 Mar;3(1):9-16. doi: 10.1007/s11739-008-0089-3. Epub 2008 - Mar 7. - -PMID- 23662778 -OWN - NLM -STAT- MEDLINE -DCOM- 20140221 -LR - 20130718 -IS - 1545-4274 (Electronic) -IS - 1523-9829 (Linking) -VI - 15 -DP - 2013 -TI - Cardiovascular magnetic resonance: deeper insights through bioengineering. -PG - 433-61 -LID - 10.1146/annurev-bioeng-071812-152346 [doi] -AB - Heart disease is the main cause of morbidity and mortality worldwide, with - coronary artery disease, diabetes, and obesity being major contributing factors. - Cardiovascular magnetic resonance (CMR) can provide a wealth of quantitative - information on the performance of the heart, without risk to the patient. - Quantitative analyses of these data can substantially augment the diagnostic - quality of CMR examinations and can lead to more effective characterization of - disease and quantification of treatment benefit. This review provides an overview - of the current state of the art in CMR with particular regard to the - quantification of motion, both microscopic and macroscopic, and the application - of bioengineering analysis for the evaluation of cardiac mechanics. We discuss - the current clinical practice and the likely advances in the next 5-10 years, as - well as the ways in which clinical examinations can be augmented by - bioengineering analysis of strain, compliance, and stress. -FAU - Young, A A -AU - Young AA -AD - Department of Anatomy with Radiology, School of Medical Science, Faculty of - Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand. - a.young@auckland.ac.nz -FAU - Prince, J L -AU - Prince JL -LA - eng -GR - R01HL087773/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130506 -PL - United States -TA - Annu Rev Biomed Eng -JT - Annual review of biomedical engineering -JID - 100883581 -RN - 0 (Contrast Media) -SB - IM -MH - Animals -MH - Bioengineering/*methods -MH - Biomechanical Phenomena -MH - Cardiovascular System/*pathology -MH - Contrast Media/chemistry -MH - Fibrosis/pathology -MH - Heart/*physiology -MH - Heart Diseases/pathology -MH - Humans -MH - Hypertrophy/pathology -MH - Magnetic Resonance Imaging/*methods -MH - Magnetics -MH - Models, Statistical -MH - Motion -MH - Perfusion -MH - Probability -MH - Stress, Mechanical -EDAT- 2013/05/15 06:00 -MHDA- 2014/02/22 06:00 -CRDT- 2013/05/14 06:00 -PHST- 2013/05/14 06:00 [entrez] -PHST- 2013/05/15 06:00 [pubmed] -PHST- 2014/02/22 06:00 [medline] -AID - 10.1146/annurev-bioeng-071812-152346 [doi] -PST - ppublish -SO - Annu Rev Biomed Eng. 2013;15:433-61. doi: 10.1146/annurev-bioeng-071812-152346. - Epub 2013 May 6. - -PMID- 18335668 -OWN - NLM -STAT- MEDLINE -DCOM- 20080520 -LR - 20240426 -IS - 1470-2118 (Print) -IS - 1473-4893 (Electronic) -IS - 1470-2118 (Linking) -VI - 8 -IP - 1 -DP - 2008 Feb -TI - Recent developments in acute coronary syndromes. -PG - 42-8 -AB - Coronary artery disease is the leading cause of death in the UK with a high - clinical, social and economic burden. The management of acute coronary syndromes - is rapidly evolving and clinicians are constantly challenged with incorporating - new clinical pathways and guidelines into their practices. It is important for - clinicians to have a sound working knowledge of acute coronary syndromes, and be - updated on the emerging evidence to guide therapy and improve outcomes in these - patients. -FAU - Iqbal, M Bilal -AU - Iqbal MB -AD - The Heart Hospital, University College London Hospitals NHS Trust. - biqbal@excite.com -FAU - Westwood, Mark A -AU - Westwood MA -FAU - Swanton, R Howard -AU - Swanton RH -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Clin Med (Lond) -JT - Clinical medicine (London, England) -JID - 101092853 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Anticoagulants) -RN - 0 (Antithrombins) -RN - 0 (Heparin, Low-Molecular-Weight) -RN - 0 (Hirudins) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Peptide Fragments) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Platelet Glycoprotein GPIIb-IIIa Complex) -RN - 0 (Polysaccharides) -RN - 0 (Recombinant Proteins) -RN - A74586SNO7 (Clopidogrel) -RN - J177FOW5JL (Fondaparinux) -RN - OM90ZUW7M1 (Ticlopidine) -RN - TN9BEX005G (bivalirudin) -SB - IM -MH - *Angioplasty, Balloon, Coronary/methods -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Anticoagulants/therapeutic use -MH - Antithrombins/therapeutic use -MH - Clopidogrel -MH - Fondaparinux -MH - Heparin, Low-Molecular-Weight/therapeutic use -MH - Hirudins -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Myocardial Infarction/drug therapy/mortality/prevention & control/*therapy -MH - Peptide Fragments/therapeutic use -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors -MH - Polysaccharides/therapeutic use -MH - Recombinant Proteins/therapeutic use -MH - *Thrombolytic Therapy -MH - Ticlopidine/analogs & derivatives/therapeutic use -PMC - PMC4953708 -EDAT- 2008/03/14 09:00 -MHDA- 2008/05/21 09:00 -PMCR- 2008/02/01 -CRDT- 2008/03/14 09:00 -PHST- 2008/03/14 09:00 [pubmed] -PHST- 2008/05/21 09:00 [medline] -PHST- 2008/03/14 09:00 [entrez] -PHST- 2008/02/01 00:00 [pmc-release] -AID - S1470-2118(24)00321-X [pii] -AID - clinmedicine [pii] -AID - 10.7861/clinmedicine.8-1-42 [doi] -PST - ppublish -SO - Clin Med (Lond). 2008 Feb;8(1):42-8. doi: 10.7861/clinmedicine.8-1-42. - -PMID- 23249567 -OWN - NLM -STAT- MEDLINE -DCOM- 20130528 -LR - 20181202 -IS - 1473-5733 (Electronic) -IS - 0957-5235 (Linking) -VI - 24 -IP - 1 -DP - 2013 Jan -TI - Takotsubo syndrome: an underdiagnosed complication of 5-fluorouracil mimicking - acute myocardial infarction. -PG - 90-4 -LID - 10.1097/MBC.0b013e3283597605 [doi] -AB - Takotsubo syndrome (TTS)/cardiomyopathy is a syndrome that mimics acute - myocardial infarction in the absence of coronary artery disease and is - characterized by acute onset of chest pain, electrocardiographic abnormalities, - and reversible left ventricular dysfunction. It is usually induced by emotional - and physical stress. Fluorouracil is one of the most frequently used chemotherapy - agents and a relatively common adverse reaction of fluorouracil is - cardiotoxicity. Herein we describe a patient without a history of cardiovascular - disorder who developed severe heart failure during infusion of fluorouracil for - metastatic gastric cancer. Remarkably, the patient did not develop TTS during - prior chemotherapy regimen, which also included fluorouracil. The patient's - findings were consistent with the proposed TTS diagnostic criteria and coronary - angiography was normal, without obstructive coronary artery disease. With - supportive care, the patient's cardiac functions returned to normal. TTS is not a - well known syndrome to clinicians and this condition appears to occur more - frequently than previously thought. In addition to the presented case, a review - of the clinical features and outcome of 10 reported cases of fluorouracil-induced - TTS is presented. -FAU - Ozturk, Mehmet A -AU - Ozturk MA -AD - Department of Internal Medicine, Yeditepe University Hospital, Istanbul, Turkey. - mehmet.ozturk@yeditepe.edu.tr -FAU - Ozveren, Olcay -AU - Ozveren O -FAU - Cinar, Veysel -AU - Cinar V -FAU - Erdik, Baran -AU - Erdik B -FAU - Oyan, Basak -AU - Oyan B -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - England -TA - Blood Coagul Fibrinolysis -JT - Blood coagulation & fibrinolysis : an international journal in haemostasis and - thrombosis -JID - 9102551 -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Antimetabolites, Antineoplastic) -RN - 0 (Taxoids) -RN - 15H5577CQD (Docetaxel) -RN - 7673326042 (Irinotecan) -RN - N3RQ532IUT (Amiodarone) -RN - Q20Q21Q62J (Cisplatin) -RN - Q573I9DVLP (Leucovorin) -RN - U3P01618RT (Fluorouracil) -RN - XT3Z54Z28A (Camptothecin) -SB - IM -MH - Amiodarone/therapeutic use -MH - Anti-Arrhythmia Agents/therapeutic use -MH - Antimetabolites, Antineoplastic/administration & dosage/*adverse effects -MH - Antineoplastic Combined Chemotherapy Protocols/therapeutic use -MH - Camptothecin/administration & dosage/analogs & derivatives -MH - Cisplatin/administration & dosage -MH - Combined Modality Therapy -MH - Coronary Angiography -MH - *Diagnostic Errors -MH - Docetaxel -MH - Electric Countershock -MH - Fatal Outcome -MH - Fluorouracil/administration & dosage/*adverse effects -MH - Gastrectomy -MH - Humans -MH - Irinotecan -MH - Leucovorin/administration & dosage -MH - Lymphatic Metastasis -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/diagnosis/diagnostic imaging -MH - Peritoneal Neoplasms/complications/secondary -MH - Peritonitis/complications/drug therapy -MH - Stomach Neoplasms/drug therapy/surgery -MH - Takotsubo Cardiomyopathy/*chemically induced/diagnosis/diagnostic imaging -MH - Taxoids/administration & dosage -MH - Ventricular Fibrillation/drug therapy/etiology/therapy -EDAT- 2012/12/20 06:00 -MHDA- 2013/05/29 06:00 -CRDT- 2012/12/20 06:00 -PHST- 2012/12/20 06:00 [entrez] -PHST- 2012/12/20 06:00 [pubmed] -PHST- 2013/05/29 06:00 [medline] -AID - 00001721-201301000-00016 [pii] -AID - 10.1097/MBC.0b013e3283597605 [doi] -PST - ppublish -SO - Blood Coagul Fibrinolysis. 2013 Jan;24(1):90-4. doi: - 10.1097/MBC.0b013e3283597605. - -PMID- 19848025 -OWN - NLM -STAT- MEDLINE -DCOM- 20091208 -LR - 20161124 -IS - 0019-4832 (Print) -IS - 0019-4832 (Linking) -VI - 60 -IP - 3 Suppl C -DP - 2008 Nov-Dec -TI - Prime time use of tissue Doppler echocardiography: what have we gained? -PG - C10-25 -AB - In daily practice, Tissue Doppler Echocardiography (TDI) is used to estimate left - ventricular filling pressures, categorize diastolic dysfunction, identify - patients with heart failure (HF) with normal ejection fraction, differentiate - constrictive pericarditis from restrictive cardiomyopathy, to prognosticate acute - coronary syndrome, valvular heart disease syndrome of HF etc, correlate exercise - capacity and symptoms, differentiate physiological versus pathological - hypertrophy, assessment of intraventricular dyssynchrony, regional and global - systolic and diastolic properties, detection of right ventricular function and - possible carriers of genetic cardiomyopathies like Fabry's disease and - hypertrophic cardiomyopathy, etc. Its role in adding incremental value to stress - echocardiography, subclinical dysfunction evaluation, cardiac transplant - rejection, cardiotoxicity of anti-cancer drugs, predicting occurrence and - reversion of atrial fibrillation, predicting aortic catastrophies etc, although - very encouraging has not found many users. It was intuitively considered - invaluable in detecting subclinical myocarditis, acute rheumatic fever, Chaga's - disease and localization of atrioventricular accessory pathways with manifest - conduction, but could not find prime time readiness. In a similar manner, - tissue-velocity derived deformation parameters have not found prime time use, - despite making great inroads into the mysteries of muscle mechanics. Part of the - problem lies in their emphasis on unidirectional information of a structure which - is essentially multidimensional. The other problems have been angle-dependency - and low signal-to-noise ratio in deformation imaging which has restricted its use - to highly experienced operators rather than more democratic use. Validation - studies did indicate its great potential. TDI-derived imaging paved the way for - non-Doppler multidimensional deformation imaging which is slowly gaining ground. -FAU - Mohan, Jagdish C -AU - Mohan JC -AD - Department of Cardiology, Ridge Heart Centre, Sunder Lal Jain Hospital, Ashok - Vihar-III, Delhi-52, India. jcmohan@vsnl.com -FAU - Tomar, Deepak -AU - Tomar D -FAU - Mohan, Vipul -AU - Mohan V -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian Heart J -JT - Indian heart journal -JID - 0374675 -SB - IM -MH - Diagnosis, Differential -MH - Echocardiography, Doppler/*methods -MH - Heart Diseases/*diagnostic imaging/physiopathology -MH - Heart Ventricles/diagnostic imaging/*physiopathology -MH - Humans -MH - Myocardial Contraction/*physiology -MH - Reproducibility of Results -MH - Stroke Volume/*physiology -RF - 58 -EDAT- 2009/10/24 06:00 -MHDA- 2009/12/16 06:00 -CRDT- 2009/10/24 06:00 -PHST- 2009/10/24 06:00 [entrez] -PHST- 2009/10/24 06:00 [pubmed] -PHST- 2009/12/16 06:00 [medline] -PST - ppublish -SO - Indian Heart J. 2008 Nov-Dec;60(3 Suppl C):C10-25. - -PMID- 23701985 -OWN - NLM -STAT- MEDLINE -DCOM- 20140624 -LR - 20161125 -IS - 1879-1336 (Electronic) -IS - 1054-8807 (Linking) -VI - 22 -IP - 6 -DP - 2013 Nov-Dec -TI - Double-chambered right ventricle: a review. -PG - 417-23 -LID - S1054-8807(13)00107-5 [pii] -LID - 10.1016/j.carpath.2013.03.004 [doi] -AB - A double-chambered right ventricle is a rare heart defect in which the right - ventricle is separated into a high-pressure proximal and low-pressure distal - chamber. This defect is considered to be congenital and typically presents in - infancy or childhood but has been reported to present rarely in adults. It can be - caused by the presence of anomalous muscle tissue, hypertrophy of the endogenous - trabecular bands, or an aberrant moderator band; all of which will typically - result in progressive obstruction of the outflow tract. In this paper, we will - discuss the general anatomy of the right ventricle, the relevant embryology of - the heart, and the presentation, diagnosis, and treatment of a double-chambered - right ventricle. -CI - Copyright © 2013. Published by Elsevier Inc. -FAU - Loukas, Marios -AU - Loukas M -AD - Department of Anatomical Sciences, School of Medicine, St George's University, - Grenada, West Indies. Electronic address: mloukas@sgu.edu. -FAU - Housman, Brian -AU - Housman B -FAU - Blaak, Christa -AU - Blaak C -FAU - Kralovic, Sarah -AU - Kralovic S -FAU - Tubbs, R Shane -AU - Tubbs RS -FAU - Anderson, Robert H -AU - Anderson RH -LA - eng -PT - Journal Article -PT - Review -DEP - 20130520 -PL - United States -TA - Cardiovasc Pathol -JT - Cardiovascular pathology : the official journal of the Society for Cardiovascular - Pathology -JID - 9212060 -SB - IM -MH - Coronary Angiography -MH - Disease Progression -MH - Echocardiography, Doppler, Color -MH - Heart Defects, Congenital/complications/*pathology/physiopathology/therapy -MH - Heart Ventricles/*abnormalities/diagnostic imaging/physiopathology/surgery -MH - Humans -MH - Hypertrophy -MH - Magnetic Resonance Imaging -MH - Predictive Value of Tests -MH - Prognosis -MH - Ventricular Function, Right -MH - Ventricular Outflow Obstruction/etiology -MH - Ventricular Pressure -OTO - NOTNLM -OT - Anomalous muscle band -OT - Congenital heart disease -OT - Crista supraventricularis -OT - Heart defect -OT - Moderator band -OT - Septoparietal trabeculations -OT - Subinfundibular pulmonary stenosis -EDAT- 2013/05/25 06:00 -MHDA- 2014/06/25 06:00 -CRDT- 2013/05/25 06:00 -PHST- 2012/10/12 00:00 [received] -PHST- 2013/03/16 00:00 [revised] -PHST- 2013/03/18 00:00 [accepted] -PHST- 2013/05/25 06:00 [entrez] -PHST- 2013/05/25 06:00 [pubmed] -PHST- 2014/06/25 06:00 [medline] -AID - S1054-8807(13)00107-5 [pii] -AID - 10.1016/j.carpath.2013.03.004 [doi] -PST - ppublish -SO - Cardiovasc Pathol. 2013 Nov-Dec;22(6):417-23. doi: 10.1016/j.carpath.2013.03.004. - Epub 2013 May 20. - -PMID- 18038566 -OWN - NLM -STAT- MEDLINE -DCOM- 20071220 -LR - 20071127 -IS - 0023-2149 (Print) -IS - 0023-2149 (Linking) -VI - 85 -IP - 9 -DP - 2007 -TI - [On the use of statins in patients with chronic cardiac insufficiency]. -PG - 40-4 -AB - Today, the necessity to use hypolipidemic agents belonging to the group of - statins as means of primary and secondary prevention of coronary artery disease - (CAD) and its complications is not doubted. The results of numerous large studies - conducted in many different countries during the last 10 to 15 years confirm this - statement. The appropriateness of statin application to patients with chronic - cardiac insufficiency (CCI) is still under discussion, because there are no - sufficient data on whether hypolipidemic therapy is able to improve the prognosis - in this category of patients. The authors conducted a long-term research into the - use of statins in combination with basic combined therapy in patients with CCI - complicating the course of CAD. A reverse correlation between the levels of total - cholesterol, low-density protein cholesterol, and the degree of CCI severity was - demonstrated. Long-term continuous therapy of CCI patients with a combination of - medications including statins did not worsen the clinical symptoms. However, - hypolipidemic therapy should be administered to CCI patients on a differentiated - basis, taking into account the initial state of lipid profile and the severity of - the underlying disease. -FAU - Ol'binskaia, L I -AU - Ol'binskaia LI -FAU - Sizova, Zh M -AU - Sizova ZhM -FAU - Zakharova, V L -AU - Zakharova VL -LA - rus -PT - English Abstract -PT - Journal Article -PT - Review -PL - Russia (Federation) -TA - Klin Med (Mosk) -JT - Klinicheskaia meditsina -JID - 2985204R -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Chronic Disease -MH - Disease Progression -MH - Heart Failure/*drug therapy -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Treatment Outcome -RF - 24 -EDAT- 2007/11/28 09:00 -MHDA- 2007/12/21 09:00 -CRDT- 2007/11/28 09:00 -PHST- 2007/11/28 09:00 [pubmed] -PHST- 2007/12/21 09:00 [medline] -PHST- 2007/11/28 09:00 [entrez] -PST - ppublish -SO - Klin Med (Mosk). 2007;85(9):40-4. - -PMID- 20620709 -OWN - NLM -STAT- MEDLINE -DCOM- 20100806 -LR - 20220410 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 56 -IP - 1 -DP - 2010 Jun 29 -TI - Risk factors for venous thromboembolism. -PG - 1-7 -LID - 10.1016/j.jacc.2010.01.057 [doi] -AB - Risk factors for venous thromboembolism (VTE) are often modifiable and overlap - with risk factors for coronary artery disease. Encouraging our patients to adopt - a heart-healthy lifestyle by abstaining from cigarettes, maintaining lean weight, - limiting red meat intake, and controlling hypertension might lower the risk of - pulmonary embolism and deep vein thrombosis (DVT), although a cause-effect - relationship has not been firmly established. For hospitalized patients, - guidelines have provided evidence-based strategies to identify patients at risk, - such as elderly persons and those with cancer, congestive heart failure, or - chronic obstructive pulmonary disease or undergoing major surgery. Most should - receive pharmacological prophylaxis, which will minimize the risk of VTE. Because - approximately 3 of every 4 pulmonary embolism and DVT events occur outside the - hospital setting, patients should also be assessed for persistent high-risk of - VTE at the time of hospital discharge. -CI - Copyright (c) 2010 American College of Cardiology Foundation. Published by - Elsevier Inc. All rights reserved. -FAU - Goldhaber, Samuel Z -AU - Goldhaber SZ -AD - Harvard Medical School, Venous Thromboembolism Research Group, Cardiovascular - Division, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. - sgoldhaber@partners.org -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Child -MH - Female -MH - Humans -MH - Inpatients -MH - Life Style -MH - Pregnancy -MH - Pregnancy Complications -MH - Recurrence -MH - Registries -MH - Risk Factors -MH - Thrombosis/complications -MH - Venous Thromboembolism/*etiology/genetics/prevention & control -RF - 73 -EDAT- 2010/07/14 06:00 -MHDA- 2010/08/07 06:00 -CRDT- 2010/07/13 06:00 -PHST- 2009/05/29 00:00 [received] -PHST- 2010/01/22 00:00 [revised] -PHST- 2010/01/25 00:00 [accepted] -PHST- 2010/07/13 06:00 [entrez] -PHST- 2010/07/14 06:00 [pubmed] -PHST- 2010/08/07 06:00 [medline] -AID - S0735-1097(10)01525-1 [pii] -AID - 10.1016/j.jacc.2010.01.057 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2010 Jun 29;56(1):1-7. doi: 10.1016/j.jacc.2010.01.057. - -PMID- 18342773 -OWN - NLM -STAT- MEDLINE -DCOM- 20080626 -LR - 20161124 -IS - 1076-6332 (Print) -IS - 1076-6332 (Linking) -VI - 15 -IP - 4 -DP - 2008 Apr -TI - MDCT of the myocardium: a new contribution to ischemic heart disease. -PG - 477-87 -LID - 10.1016/j.acra.2007.11.004 [doi] -AB - RATIONALE AND OBJECTIVES: Despite the progress made in diagnosis and treatment, - cardiovascular diseases remain the main cause of death worldwide. MATERIALS AND - METHODS: Multidetector row computed tomography (MDCT) provides several diagnostic - insights, namely assessment of coronary artery anatomy and measurement of left - ventricular volume and function. The ability of CT to show myocardial infarcted - areas as an enhanced territory was described in the late 1970s in an animal - model. RESULTS: This method found a second wind with the arrival of MDCT - technology that led to its clinical application. Several authors describe the - ability of MDCT to assess myocardial injury both in animals and humans. The MDCT - assessment of myocardial late enhancement is based on the same principle as - delayed enhancement MRI. CONCLUSIONS: The aim of this review is to cover the - technical aspects of cardiac MDCT in assessing the myocardium and its potential - in diagnosing ischemic heart disease. -FAU - Jacquier, Alexis -AU - Jacquier A -AD - Department of Radiology, Hopital de la Timone, University of Marseille - Méditerranée, 264 rue St Pierre, 13385 Marseille Cedex 5, France. - alexis.jacquier@ap-hm.fr -FAU - Revel, Didier -AU - Revel D -FAU - Saeed, Maythem -AU - Saeed M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Acad Radiol -JT - Academic radiology -JID - 9440159 -RN - 0 (Contrast Media) -SB - IM -MH - Contrast Media -MH - Humans -MH - Myocardial Ischemia/*diagnostic imaging -MH - Tomography, X-Ray Computed/*methods -RF - 48 -EDAT- 2008/03/18 09:00 -MHDA- 2008/06/27 09:00 -CRDT- 2008/03/18 09:00 -PHST- 2007/10/12 00:00 [received] -PHST- 2007/11/07 00:00 [revised] -PHST- 2007/11/08 00:00 [accepted] -PHST- 2008/03/18 09:00 [pubmed] -PHST- 2008/06/27 09:00 [medline] -PHST- 2008/03/18 09:00 [entrez] -AID - S1076-6332(07)00671-X [pii] -AID - 10.1016/j.acra.2007.11.004 [doi] -PST - ppublish -SO - Acad Radiol. 2008 Apr;15(4):477-87. doi: 10.1016/j.acra.2007.11.004. - -PMID- 19475778 -OWN - NLM -STAT- MEDLINE -DCOM- 20090619 -LR - 20211020 -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Print) -IS - 1176-6344 (Linking) -VI - 5 -IP - 1 -DP - 2009 -TI - Choice of ACE inhibitor combinations in hypertensive patients with type 2 - diabetes: update after recent clinical trials. -PG - 411-27 -AB - The diabetes epidemic continues to grow unabated, with a staggering toll in - micro- and macrovascular complications, disability, and death. Diabetes causes a - two- to fourfold increase in the risk of cardiovascular disease, and represents - the first cause of dialysis treatment both in the UK and the US. Concomitant - hypertension doubles total mortality and stroke risk, triples the risk of - coronary heart disease and significantly hastens the progression of microvascular - complications, including diabetic nephropathy. Therefore, blood pressure - reduction is of particular importance in preventing cardiovascular and renal - outcomes. Successful antihypertensive treatment will often require a combination - therapy, either with separate drugs or with fixed-dose combinations. Angiotensin - converting enzyme (ACE) inhibitor plus diuretic combination therapy improves - blood pressure control, counterbalances renin-angiotensin system activation due - to diuretic therapy and reduces the risk of electrolyte alterations, obtaining at - the same time synergistic antiproteinuric effects. ACE inhibitor plus calcium - channel blocker provides a significant additive effect on blood pressure - reduction, may have favorable metabolic effects and synergistically reduce - proteinuria and the rate of decline in glomerular filtration rate, as evidenced - by the GUARD trial. Finally, the recently published ACCOMPLISH trial showed that - an ACE inhibitor/calcium channel blocker combination may be particularly useful - in reducing cardiovascular outcomes in high-risk patients. The present review - will focus on different ACE inhibitor combinations in the treatment of patients - with type 2 diabetes mellitus and hypertension, in the light of recent clinical - trials, including GUARD and ACCOMPLISH. -FAU - Reboldi, Gianpaolo -AU - Reboldi G -AD - 1Department of internal Medicine. University of Perugia, Perugia, Italy. - paolo@unipg.it -FAU - Gentile, Giorgio -AU - Gentile G -FAU - Angeli, Fabio -AU - Angeli F -FAU - Verdecchia, Paolo -AU - Verdecchia P -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Antihypertensive Agents) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Diuretics) -RN - 0 (Drug Combinations) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin II Type 1 Receptor Blockers/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/*therapeutic use -MH - Antihypertensive Agents/*therapeutic use -MH - Blood Pressure/drug effects -MH - Calcium Channel Blockers/*therapeutic use -MH - Cardiovascular Diseases/etiology/prevention & control -MH - Clinical Trials as Topic -MH - Diabetes Mellitus, Type 2/complications/*drug therapy/physiopathology -MH - Diabetic Nephropathies/etiology/prevention & control -MH - Diuretics/*therapeutic use -MH - Drug Combinations -MH - Humans -MH - Hypertension/complications/*drug therapy/physiopathology -MH - Patient Selection -MH - Practice Guidelines as Topic -MH - Renin-Angiotensin System/drug effects -MH - Treatment Outcome -PMC - PMC2686259 -EDAT- 2009/05/30 09:00 -MHDA- 2009/06/20 09:00 -PMCR- 2009/05/21 -CRDT- 2009/05/30 09:00 -PHST- 2009/05/30 09:00 [entrez] -PHST- 2009/05/30 09:00 [pubmed] -PHST- 2009/06/20 09:00 [medline] -PHST- 2009/05/21 00:00 [pmc-release] -AID - vhrm-5-411 [pii] -AID - 10.2147/vhrm.s4235 [doi] -PST - ppublish -SO - Vasc Health Risk Manag. 2009;5(1):411-27. doi: 10.2147/vhrm.s4235. - -PMID- 28465893 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20201001 -IS - 2211-4122 (Print) -IS - 2347-193X (Electronic) -IS - 2211-4122 (Linking) -VI - 23 -IP - 4 -DP - 2013 Oct-Dec -TI - The Ventricular-Arterial Coupling: From Basic Pathophysiology to Clinical - Application in the Echocardiography Laboratory. -PG - 91-95 -LID - 10.4103/2211-4122.127408 [doi] -AB - The interplay between cardiac function and arterial system, which in turn affects - ventricular performance, is defined commonly ventricular-arterial coupling and is - an expression of global cardiovascular efficiency. This relation can be expressed - in mathematical terms as the ratio between arterial elastance (EA) and - end-systolic elastance (EES) of the left ventricle (LV). The noninvasive - calculation requires complicated formulae, which can be, however, easily - implemented in computerized algorithms, allowing the adoption of this index in - the clinical evaluation of patients. This review summarizes the up-to-date - literature on the topic, with particular focus on the main clinical studies, - which range over different clinical scenarios, namely hypertension, heart - failure, coronary artery disease, and valvular heart disease. -FAU - Antonini-Canterin, Francesco -AU - Antonini-Canterin F -AD - Cardiologia Preventiva e Riabilitativa, Azienda Ospedaliera S. Maria degli - Angeli, Pordenone, Italy. -FAU - Poli, Stefano -AU - Poli S -AD - Cardiologia Preventiva e Riabilitativa, Azienda Ospedaliera S. Maria degli - Angeli, Pordenone, Italy. -AD - Scuola di Specializzazione in Malattie Cardiovascolari, Università di Trieste, - Trieste, Italy. -FAU - Vriz, Olga -AU - Vriz O -AD - Cardiologia, San Daniele del Friuli, Università di Pisa, Pisa, University of - Pisa, Pisa, Italy. -FAU - Pavan, Daniela -AU - Pavan D -AD - Cardiologia, San Vito al Tagliamento, Università di Pisa, Pisa, University of - Pisa, Pisa, Italy. -FAU - Bello, Vitantonio Di -AU - Bello VD -AD - Dipartimento Cardiotoracico e Vascolare, Università di Pisa, Pisa, University of - Pisa, Pisa, Italy. -FAU - Nicolosi, Gian Luigi -AU - Nicolosi GL -AD - Cardiologia, Azienda Ospedaliera S. Maria degli Angeli, Pordenone, Italy. -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - J Cardiovasc Echogr -JT - Journal of cardiovascular echography -JID - 101562228 -PMC - PMC5353400 -OTO - NOTNLM -OT - Echocardiography -OT - hypertension -OT - left ventricular function -OT - ventricular-arterial coupling -COIS- Conflict of Interest: None declared. -EDAT- 2013/10/01 00:00 -MHDA- 2013/10/01 00:01 -PMCR- 2013/10/01 -CRDT- 2017/05/04 06:00 -PHST- 2017/05/04 06:00 [entrez] -PHST- 2013/10/01 00:00 [pubmed] -PHST- 2013/10/01 00:01 [medline] -PHST- 2013/10/01 00:00 [pmc-release] -AID - JCE-23-91 [pii] -AID - 10.4103/2211-4122.127408 [doi] -PST - ppublish -SO - J Cardiovasc Echogr. 2013 Oct-Dec;23(4):91-95. doi: 10.4103/2211-4122.127408. - -PMID- 22927798 -OWN - NLM -STAT- MEDLINE -DCOM- 20121212 -LR - 20250626 -IS - 1549-1676 (Electronic) -IS - 1549-1277 (Print) -IS - 1549-1277 (Linking) -VI - 9 -IP - 8 -DP - 2012 -TI - Effects of intensive blood pressure lowering on cardiovascular and renal - outcomes: a systematic review and meta-analysis. -PG - e1001293 -LID - 10.1371/journal.pmed.1001293 [doi] -LID - e1001293 -AB - BACKGROUND: Guidelines recommend intensive blood pressure (BP) lowering in - patients at high risk. While placebo-controlled trials have demonstrated 22% - reductions in coronary heart disease (CHD) and stroke associated with a 10-mmHg - difference in systolic BP, it is unclear if more intensive BP lowering strategies - are associated with greater reductions in risk of CHD and stroke. We did a - systematic review to assess the effects of intensive BP lowering on vascular, - eye, and renal outcomes. METHODS AND FINDINGS: We systematically searched - Medline, Embase, and the Cochrane Library for trials published between 1950 and - July 2011. We included trials that randomly assigned individuals to different - target BP levels. We identified 15 trials including a total of 37,348 - participants. On average there was a 7.5/4.5-mmHg BP difference. Intensive BP - lowering achieved relative risk (RR) reductions of 11% for major cardiovascular - events (95% CI 1%-21%), 13% for myocardial infarction (0%-25%), 24% for stroke - (8%-37%), and 11% for end stage kidney disease (3%-18%). Intensive BP lowering - regimens also produced a 10% reduction in the risk of albuminuria (4%-16%), and a - trend towards benefit for retinopathy (19%, 0%-34%, p = 0.051) in patients with - diabetes. There was no clear effect on cardiovascular or noncardiovascular death. - Intensive BP lowering was well tolerated; with serious adverse events uncommon - and not significantly increased, except for hypotension (RR 4.16, 95% CI 2.25 to - 7.70), which occurred infrequently (0.4% per 100 person-years). CONCLUSIONS: - Intensive BP lowering regimens provided greater vascular protection than standard - regimens that was proportional to the achieved difference in systolic BP, but did - not have any clear impact on the risk of death or serious adverse events. Further - trials are required to more clearly define the risks and benefits of BP targets - below those currently recommended, given the benefits suggested by the currently - available data. -FAU - Lv, Jicheng -AU - Lv J -AD - The George Institute for Global Health, The University of Sydney, Sydney, - Australia. -FAU - Neal, Bruce -AU - Neal B -FAU - Ehteshami, Parya -AU - Ehteshami P -FAU - Ninomiya, Toshiharu -AU - Ninomiya T -FAU - Woodward, Mark -AU - Woodward M -FAU - Rodgers, Anthony -AU - Rodgers A -FAU - Wang, Haiyan -AU - Wang H -FAU - MacMahon, Stephen -AU - MacMahon S -FAU - Turnbull, Fiona -AU - Turnbull F -FAU - Hillis, Graham -AU - Hillis G -FAU - Chalmers, John -AU - Chalmers J -FAU - Perkovic, Vlado -AU - Perkovic V -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20120821 -PL - United States -TA - PLoS Med -JT - PLoS medicine -JID - 101231360 -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Antihypertensive Agents/adverse effects/*pharmacology/therapeutic use -MH - Blood Pressure/*drug effects -MH - Cardiovascular Diseases/drug therapy/pathology/physiopathology -MH - Cardiovascular System/*drug effects/pathology/*physiopathology -MH - Clinical Trials as Topic -MH - Humans -MH - Kidney/*drug effects/*physiopathology -MH - Kidney Diseases/drug therapy/pathology/physiopathology -MH - Regression Analysis -MH - Risk Factors -MH - Treatment Outcome -PMC - PMC3424246 -COIS- JL has received grant support from Pfizer for hypertension research. VP, MW, SM, - and JC have received honoraria from Servier for scientific presentations relating - to blood pressure. SM and JC were principal investigators on ADVANCE, a blood - pressure lowering trial funded by Servier and the Australian National Health and - Medical Research Council. BN has received BP-related research support from - Servier, and honoraria for scientific presentations related to blood pressure - from Novartis, Tanabe, and Servier. AR has received an unrestricted grant from Dr - Reddy’s Laboratories for a trial that includes blood pressure-lowering agents. - PE, FT, TN, HW, and GH declare they have no competing interests. -EDAT- 2012/08/29 06:00 -MHDA- 2012/12/13 06:00 -PMCR- 2012/08/21 -CRDT- 2012/08/29 06:00 -PHST- 2011/10/07 00:00 [received] -PHST- 2012/07/06 00:00 [accepted] -PHST- 2012/08/29 06:00 [entrez] -PHST- 2012/08/29 06:00 [pubmed] -PHST- 2012/12/13 06:00 [medline] -PHST- 2012/08/21 00:00 [pmc-release] -AID - PMEDICINE-D-11-02459 [pii] -AID - 10.1371/journal.pmed.1001293 [doi] -PST - ppublish -SO - PLoS Med. 2012;9(8):e1001293. doi: 10.1371/journal.pmed.1001293. Epub 2012 Aug - 21. - -PMID- 19174052 -OWN - NLM -STAT- MEDLINE -DCOM- 20090501 -LR - 20190917 -IS - 1579-2242 (Electronic) -IS - 0300-8932 (Linking) -VI - 62 Suppl 1 -DP - 2009 Jan -TI - [Update on ischemic heart disease]. -PG - 80-91 -AB - This article contains a review of the main developments reported during 2008 in - either publications or presentations on the pathophysiology, secondary - prevention, prognosis or treatment of ST-segment elevation, or non-ST-segment - elevation acute coronary syndrome. The latest clinical practice guidelines are - also summarized and discussed. -FAU - Barrabés, José A -AU - Barrabés JA -AD - Servicio de Cardiología, Hospital Universitario Vall d'Hebron, Barcelona, España. - jabarrabes@vhebron.net -FAU - Sanchís, Juan -AU - Sanchís J -FAU - Sánchez, Pedro L -AU - Sánchez PL -FAU - Bardají, Alfredo -AU - Bardají A -LA - spa -PT - English Abstract -PT - Journal Article -PT - Review -TT - Actualización en cardiopatía isquémica. -PL - Spain -TA - Rev Esp Cardiol -JT - Revista espanola de cardiologia -JID - 0404277 -SB - IM -MH - Electrocardiography -MH - Humans -MH - Myocardial Infarction/etiology/prevention & control -MH - Myocardial Ischemia/diagnosis/physiopathology/prevention & control/*therapy -MH - Prognosis -RF - 71 -EDAT- 2009/02/20 09:00 -MHDA- 2009/05/02 09:00 -CRDT- 2009/01/29 09:00 -PHST- 2009/01/29 09:00 [entrez] -PHST- 2009/02/20 09:00 [pubmed] -PHST- 2009/05/02 09:00 [medline] -AID - 13131720 [pii] -AID - 10.1016/s0300-8932(09)70043-0 [doi] -PST - ppublish -SO - Rev Esp Cardiol. 2009 Jan;62 Suppl 1:80-91. doi: 10.1016/s0300-8932(09)70043-0. - -PMID- 17702097 -OWN - NLM -STAT- MEDLINE -DCOM- 20070925 -LR - 20191110 -IS - 1262-3636 (Print) -IS - 1262-3636 (Linking) -VI - 33 Suppl 1 -DP - 2007 Apr -TI - Congestive heart failure in the elderly diabetic. -PG - S32-9 -AB - The elderly diabetic is a potential congestive heart failure patient. Cardiac - involvement is multifactorial, particularly ischemic conditions because of the - accumulation at that age of vascular risk factors and therefore the frequency of - coronary damages. The elderly diabetic very often has high blood pressure, with - the risk of developing a hypertensive heart disease. Beyond these issues, the - effects of chronic hyperglycaemia and insulin resistance on the heart - specifically alter left ventricle compliance and therefore diastolic function, - thus accelerating the effects proper to aging. No specific recommendation has - been published on the management of the elderly diabetic with congestive heart - failure. Even at an advanced age, with a clinical diagnosis of congestive heart - failure that is sometimes difficult to make, the cardiological evaluation should - be conducted rigorously within a global evaluation, and treatment should follow - the same rules as in younger patients, with great caution given to the iatrogenic - risks inherent to this population. -FAU - Verny, C -AU - Verny C -AD - Service de gériatrie, CHU de Bicêtre, Le Kremlin-Bicêtre, France. - christiane.verny@bct.aphp.fr -LA - eng -PT - Journal Article -PT - Review -PL - France -TA - Diabetes Metab -JT - Diabetes & metabolism -JID - 9607599 -RN - 0 (Blood Glucose) -RN - 0 (Hypoglycemic Agents) -SB - IM -MH - Aged -MH - Aging/*physiology -MH - Blood Glucose/metabolism -MH - Diabetic Angiopathies/drug therapy/epidemiology/*physiopathology -MH - Heart Failure/epidemiology/*physiopathology/therapy -MH - Humans -MH - Hypoglycemic Agents/therapeutic use -MH - Incidence -RF - 61 -EDAT- 2007/08/19 09:00 -MHDA- 2007/09/26 09:00 -CRDT- 2007/08/19 09:00 -PHST- 2007/08/19 09:00 [pubmed] -PHST- 2007/09/26 09:00 [medline] -PHST- 2007/08/19 09:00 [entrez] -AID - S1262-3636(07)80055-3 [pii] -AID - 10.1016/s1262-3636(07)80055-3 [doi] -PST - ppublish -SO - Diabetes Metab. 2007 Apr;33 Suppl 1:S32-9. doi: 10.1016/s1262-3636(07)80055-3. - -PMID- 24009225 -OWN - NLM -STAT- MEDLINE -DCOM- 20140428 -LR - 20140306 -IS - 1468-201X (Electronic) -IS - 1355-6037 (Linking) -VI - 100 -IP - 7 -DP - 2014 Apr -TI - Key recommendations and evidence from the NICE guideline for the acute management - of ST-segment-elevation myocardial infarction. -PG - 536-43 -LID - 10.1136/heartjnl-2013-304717 [doi] -AB - The acute management of ST-segment-elevation myocardial infarction (STEMI) has - seen significant changes in the past decade. Although the incidence has been - declining in the UK, STEMI still gives rise to around 600 hospitalised episodes - per million people each year, with many additional cases resulting in death - before hospital admission. In-hospital mortality following acute coronary - syndromes has fallen over the past 30 years from around 20% to nearer 5%, and - this improved outcome has been attributed to various factors, including timely - access to an expanding range of effective interventional and pharmacological - treatments. A formal review of the acute management of STEMI is therefore - appropriate. The recently published NICE clinical guideline (CG167: The acute - management of myocardial infarction with ST-segment elevation) provides - evidence-based guidance on the acute management of STEMI, including the choice of - reperfusion strategies, procedural aspects of the recommended interventions, the - use of additional drugs before and longside reperfusion therapies, and the - treatment of patients who are unconscious or in cardiogenic shock. The guideline - development methods and detailed reviews of the evidence considered by the - Guideline Development Group (GDG) can be found in the full version of the - guideline (http://www.nice.org.uk/CG167), and the priority recommendations are - summarised in box 1. Other related NICE clinical guidelines deal with the - diagnosis of recent-onset chest pain of suspected cardiac origin - http://www.nice.org.uk/CG95), the early management of unstable angina and - non-STEMI (http://www.nice.org.uk/CG94), and secondary prevention after - myocardial infarction (http://www.nice.org.uk/CG48, currently being updated with - publication expected end of 2013). -FAU - Harker, Martin -AU - Harker M -AD - National Clinical Guideline Centre, Royal College of Physicians, , London, UK. -FAU - Carville, Serena -AU - Carville S -FAU - Henderson, Robert -AU - Henderson R -FAU - Gray, Huon -AU - Gray H -CN - Guideline Development Group -LA - eng -PT - Journal Article -PT - Review -DEP - 20130905 -PL - England -TA - Heart -JT - Heart (British Cardiac Society) -JID - 9602087 -SB - IM -MH - Decision Trees -MH - Disease Management -MH - Humans -MH - Myocardial Infarction/physiopathology/*therapy -MH - Myocardial Reperfusion -MH - Percutaneous Coronary Intervention/methods -MH - *Practice Guidelines as Topic -MH - Thrombolytic Therapy -OTO - NOTNLM -OT - EBM -EDAT- 2013/09/07 06:00 -MHDA- 2014/04/29 06:00 -CRDT- 2013/09/07 06:00 -PHST- 2013/09/07 06:00 [entrez] -PHST- 2013/09/07 06:00 [pubmed] -PHST- 2014/04/29 06:00 [medline] -AID - heartjnl-2013-304717 [pii] -AID - 10.1136/heartjnl-2013-304717 [doi] -PST - ppublish -SO - Heart. 2014 Apr;100(7):536-43. doi: 10.1136/heartjnl-2013-304717. Epub 2013 Sep - 5. - -PMID- 27408841 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20160713 -LR - 20201001 -IS - 2322-5718 (Print) -IS - 2322-5726 (Electronic) -IS - 2322-5718 (Linking) -VI - 1 -IP - 1 -DP - 2013 Spring -TI - Evaluation of Cardiac Mitochondrial Function by a Nuclear Imaging Technique using - Technetium-99m-MIBI Uptake Kinetics. -PG - 39-43 -LID - 10.7508/aojnmb.2013.01.008 [doi] -AB - Mitochondria play an important role in energy production for the cell. The proper - function of a myocardial cell largely depends on the functional capacity of the - mitochondria. Therefore it is necessary to establish a novel and reliable method - for a non-invasive assessment of mitochondrial function and metabolism in humans. - Although originally designed for evaluating myocardial perfusion, (99m)Tc-MIBI - can be also used to evaluate cardiac mitochondrial function. In a clinical study - on ischemic heart disease, reverse redistribution of (99m)Tc-MIBI was evident - after direct percutaneous transluminal coronary angioplasty. The presence of - increased washout of (99m)Tc-MIBI was associated with the infarct-related artery - and preserved left ventricular function. In non-ischemic cardiomyopathy, an - increased washout rate of (99m)Tc-MIBI, which correlated inversely with left - ventricular ejection fraction, was observed in patients with congestive heart - failure. Increased (99m)Tc-MIBI washout was also observed in mitochondrial - myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) and in - doxorubicin-induced cardiomyopathy. Noninvasive assessment of cardiac - mitochondrial function could be greatly beneficial in monitoring possible - cardiotoxic drug use and in the evaluation of cardiac damage in clinical - medicine. -FAU - Matsuo, Shinro -AU - Matsuo S -AD - Department of Nuclear Medicine, Kanazawa University, Kanazawa, Japan. -FAU - Nakajima, Kenichi -AU - Nakajima K -AD - Department of Nuclear Medicine, Kanazawa University, Kanazawa, Japan. -FAU - Kinuya, Seigo -AU - Kinuya S -AD - Department of Nuclear Medicine, Kanazawa University, Kanazawa, Japan. -LA - eng -PT - Journal Article -PT - Review -PL - Iran -TA - Asia Ocean J Nucl Med Biol -JT - Asia Oceania journal of nuclear medicine & biology -JID - 101611092 -PMC - PMC4937671 -OTO - NOTNLM -OT - 99mTc-MIBI -OT - cardiomyopathy -OT - heart failure -OT - ischemic heart disease -OT - mitochondria -EDAT- 2013/04/01 00:00 -MHDA- 2013/04/01 00:01 -PMCR- 2013/03/01 -CRDT- 2016/07/14 06:00 -PHST- 2016/07/14 06:00 [entrez] -PHST- 2013/04/01 00:00 [pubmed] -PHST- 2013/04/01 00:01 [medline] -PHST- 2013/03/01 00:00 [pmc-release] -AID - AOJNMB-1-39 [pii] -AID - 10.7508/aojnmb.2013.01.008 [doi] -PST - ppublish -SO - Asia Ocean J Nucl Med Biol. 2013 Spring;1(1):39-43. doi: - 10.7508/aojnmb.2013.01.008. - -PMID- 21135041 -OWN - NLM -STAT- MEDLINE -DCOM- 20110512 -LR - 20101223 -IS - 1460-2385 (Electronic) -IS - 0931-0509 (Linking) -VI - 26 -IP - 1 -DP - 2011 Jan -TI - Kidney disease in cardiology. -PG - 46-50 -LID - 10.1093/ndt/gfq719 [doi] -AB - Topics covered in this review include the relation of estimated glomerular - filtration rate, proteinuria and outcome; sudden cardiac death; contrast-induced - acute kidney injury (CI-AKI); imaging; clinical trials targeting cardiovascular - disease in chronic kidney disease (CKD) patients; and treatment of ischemic heart - disease and valvular disease. Several studies reinforce the importance of CKD in - predicting mortality and make a case for redefining CKD to incorporate levels of - proteinuria in the staging system. Another study provides support for using a - combination of echocardiography and cardiac biomarkers for cardiac risk - stratification in dialysis patients. Two studies reveal ongoing interest in and - difficulty preventing CI-AKI. One study discusses chest ultrasound to detect - pulmonary congestion and potentially guide ultrafiltration and volume removal in - dialysis patients. Several clinical trials assess folic acid, statins and aspirin - for prevention of future cardiovascular events in CKD patients. Finally, several - studies compare the use of drug-eluting and bare metal stents in dialysis - patients, discuss methods of surgical coronary artery revascularization in - dialysis patients and describe testing allopurinol as a treatment for ischemic - heart disease in non-renal patients. -FAU - Herzog, Charles A -AU - Herzog CA -AD - Cardiovascular Special Studies Center, United States Renal Data System, and - Hennepin County Medical Center, University of Minnesota, Minneapolis, MN, USA. - cherzog@usrds.org -LA - eng -PT - Journal Article -PT - Review -DEP - 20101206 -PL - England -TA - Nephrol Dial Transplant -JT - Nephrology, dialysis, transplantation : official publication of the European - Dialysis and Transplant Association - European Renal Association -JID - 8706402 -SB - IM -MH - Death, Sudden, Cardiac/*etiology -MH - Glomerular Filtration Rate -MH - Humans -MH - Kidney Failure, Chronic/*complications/physiopathology -MH - Proteinuria/physiopathology -EDAT- 2010/12/08 06:00 -MHDA- 2011/05/13 06:00 -CRDT- 2010/12/08 06:00 -PHST- 2010/12/08 06:00 [entrez] -PHST- 2010/12/08 06:00 [pubmed] -PHST- 2011/05/13 06:00 [medline] -AID - gfq719 [pii] -AID - 10.1093/ndt/gfq719 [doi] -PST - ppublish -SO - Nephrol Dial Transplant. 2011 Jan;26(1):46-50. doi: 10.1093/ndt/gfq719. Epub 2010 - Dec 6. - -PMID- 21885321 -OWN - NLM -STAT- MEDLINE -DCOM- 20111130 -LR - 20110929 -IS - 1769-6658 (Electronic) -IS - 1278-3218 (Linking) -VI - 15 -IP - 6-7 -DP - 2011 Oct -TI - [Intensity modulated radiotherapy for intrathoracic cancers: a dangerous liaison? - Our experience in the treatment of Hodgkin lymphoma mediastinal masses]. -PG - 546-8 -LID - 10.1016/j.canrad.2011.06.004 [doi] -AB - IMRT is a seducing treatment option in patients with Hodgkin lymphoma mediastinal - masses due to the complex form of the tumour masses and their proximity to organs - at risk such as the heart and the coronary arteries. This treatment delivery - technique remains risky owing to respiratory movements and heart beats. The - concomitant use of IMRT and respiratory gating is enticing, but a number of - theoretical and practical hurdles remain to be resolved before it can be used in - clinical daily practice. -CI - Copyright © 2011 Société française de radiothérapie oncologique (SFRO). Published - by Elsevier SAS. All rights reserved. -FAU - Girinsky, T -AU - Girinsky T -AD - Département des radiations, institut de cancérologie Gustave-Roussy, 114, rue - Édouard-Vaillant, 94805 Villejuif, France. girinsky@igr.fr -FAU - Ghalibafian, M -AU - Ghalibafian M -FAU - Paumier, A -AU - Paumier A -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Radiothérapie conformationnelle avec modulation d'intensité pour les tumeurs - thoraciques : une liaison dangereuse ? Expérience de l'institut Gustave-Roussy - dans le traitement des lymphomes hodgkiniens médiastinaux. -DEP - 20110831 -PL - France -TA - Cancer Radiother -JT - Cancer radiotherapie : journal de la Societe francaise de radiotherapie - oncologique -JID - 9711272 -SB - IM -MH - Academies and Institutes/statistics & numerical data -MH - France -MH - Hodgkin Disease/*radiotherapy -MH - Humans -MH - Lymphatic Irradiation/*methods -MH - Mediastinum/*radiation effects -MH - Myocardial Contraction -MH - Organs at Risk -MH - Radiation Injuries/etiology/prevention & control -MH - *Radiotherapy, Intensity-Modulated/adverse effects -MH - Respiration -EDAT- 2011/09/03 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2011/09/03 06:00 -PHST- 2011/05/07 00:00 [received] -PHST- 2011/06/16 00:00 [accepted] -PHST- 2011/09/03 06:00 [entrez] -PHST- 2011/09/03 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -AID - S1278-3218(11)00363-5 [pii] -AID - 10.1016/j.canrad.2011.06.004 [doi] -PST - ppublish -SO - Cancer Radiother. 2011 Oct;15(6-7):546-8. doi: 10.1016/j.canrad.2011.06.004. Epub - 2011 Aug 31. - -PMID- 23937437 -OWN - NLM -STAT- MEDLINE -DCOM- 20140314 -LR - 20220330 -IS - 1553-4014 (Electronic) -IS - 1553-4006 (Linking) -VI - 9 -DP - 2014 -TI - Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. -PG - 47-71 -LID - 10.1146/annurev-pathol-012513-104720 [doi] -AB - Hypoxia-inducible factors (HIFs) are transcriptional activators that function as - master regulators of oxygen homeostasis, which is disrupted in disorders - affecting the circulatory system and in cancer. The role of HIFs in these - diseases has been elucidated by clinical studies and by analyses of mouse models. - HIFs play a protective role in the pathophysiology of myocardial ischemia due to - coronary artery disease, limb ischemia due to peripheral arterial disease, - pressure-overload heart failure, wound healing, and chronic rejection of organ - transplants. In contrast, HIFs contribute to the pathogenesis of pulmonary - arterial hypertension, systemic hypertension associated with sleep apnea, ocular - neovascularization, hereditary erythrocytosis, and cancer. -FAU - Semenza, Gregg L -AU - Semenza GL -AD - Vascular Program, Institute for Cell Engineering; Departments of Pediatrics, - Medicine, Oncology, Radiation Oncology, and Biological Chemistry; and - McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School - of Medicine, Baltimore, Maryland 21205; email: gsemenza@jhmi.edu. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130807 -PL - United States -TA - Annu Rev Pathol -JT - Annual review of pathology -JID - 101275111 -RN - 0 (Hypoxia-Inducible Factor 1) -RN - S88TT14065 (Oxygen) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*metabolism -MH - Disease Models, Animal -MH - Graft Rejection/*physiopathology -MH - Humans -MH - Hypertension, Pulmonary/metabolism -MH - Hypoxia-Inducible Factor 1/*metabolism -MH - Myocardial Ischemia/metabolism -MH - Neoplasms/*metabolism -MH - Oxygen/*metabolism -MH - Wound Healing/physiology -EDAT- 2013/08/14 06:00 -MHDA- 2014/03/15 06:00 -CRDT- 2013/08/14 06:00 -PHST- 2013/08/14 06:00 [entrez] -PHST- 2013/08/14 06:00 [pubmed] -PHST- 2014/03/15 06:00 [medline] -AID - 10.1146/annurev-pathol-012513-104720 [doi] -PST - ppublish -SO - Annu Rev Pathol. 2014;9:47-71. doi: 10.1146/annurev-pathol-012513-104720. Epub - 2013 Aug 7. - -PMID- 21150006 -OWN - NLM -STAT- MEDLINE -DCOM- 20110329 -LR - 20211020 -IS - 0971-5916 (Print) -IS - 0971-5916 (Electronic) -IS - 0971-5916 (Linking) -VI - 132 -IP - 5 -DP - 2010 Nov -TI - Perspective on coronary interventions & cardiac surgeries in India. -PG - 543-8 -AB - Cardiovascular disease has become the leading cause of morbidity and mortality in - India during the last 3 decades. The genetic predisposition and acquisition of - traditional risk factors at a rapid rate as a result of urbanization seems to be - the major cause. While efforts are being made to contain this epidemic by - educating public and applying preventive measures, the ever increasing burden of - patients with symptomatic and life threatening manifestations of the disease is - posing a major challenge. This requires a concerted effort to develop modern - facilities to treat these patients. The healthcare facilities to manage these - high risk patients by contemporary methods like percutaneous coronary - revascularization and surgical methods have shown a very promising trend during - the last decade. The facilities of modern diagnostic methods and new proven - techniques to offer symptomatic relief and improve their prognosis are available - in most parts of the country. The lack of social security and health insurance - for the large majority of the population, however, is a serious limitation. - Unregulated availability of some of the newer devices for these techniques had - become a very concerning issue. However, in the last few years serious efforts - have been made to streamline these procedures. Indigenous research and scientific - data acquisition in relation to the modern technology for achieving coronary - revascularization has also started on a promising note. -FAU - Kaul, Upendra -AU - Kaul U -AD - Escorts Heart Institute, New Delhi, India. ukaul@vsnl.com -FAU - Bhatia, Vineet -AU - Bhatia V -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian J Med Res -JT - The Indian journal of medical research -JID - 0374701 -SB - IM -MH - Cardiovascular Diseases/*epidemiology/*surgery -MH - Cardiovascular Surgical Procedures/methods/*trends -MH - Delivery of Health Care/methods/*trends -MH - Health Services Accessibility/statistics & numerical data/*trends -MH - India/epidemiology -PMC - PMC3028952 -EDAT- 2010/12/15 06:00 -MHDA- 2011/03/30 06:00 -PMCR- 2010/11/01 -CRDT- 2010/12/15 06:00 -PHST- 2010/12/15 06:00 [entrez] -PHST- 2010/12/15 06:00 [pubmed] -PHST- 2011/03/30 06:00 [medline] -PHST- 2010/11/01 00:00 [pmc-release] -AID - IndianJMedRes_2010_132_5_543_73389 [pii] -AID - IJMR-132-543 [pii] -PST - ppublish -SO - Indian J Med Res. 2010 Nov;132(5):543-8. - -PMID- 21826073 -OWN - NLM -STAT- MEDLINE -DCOM- 20120120 -LR - 20211020 -IS - 1759-5010 (Electronic) -IS - 1759-5002 (Linking) -VI - 8 -IP - 10 -DP - 2011 Aug 9 -TI - Cost-effectiveness of oral antiplatelet agents--current and future perspectives. -PG - 580-91 -LID - 10.1038/nrcardio.2011.119 [doi] -AB - Cardiovascular disease is both highly prevalent and exceedingly costly to treat. - Several novel antiplatelet agents have been found to be effective in reducing the - morbidity and mortality associated with cardiovascular disease. Understanding - both the economic and the clinical implications of these novel therapies is - particularly important. In this article, the results of published evaluations of - the cost-effectiveness of oral antiplatelet strategies for use across a range of - clinical conditions and treatment settings are reviewed. The results of these - studies support the use of aspirin for primary prevention in high-risk patients - and for secondary prevention in all patients with previous cardiovascular events. - Although the optimal duration of dual antiplatelet therapy after an event remains - uncertain, favorable cost-effectiveness estimates have been demonstrated for - aspirin plus clopidogrel versus aspirin alone after a myocardial infarction or - percutaneous coronary intervention. Moreover, prasugrel has been shown to be more - cost-effective than clopidogrel for patients with an acute coronary syndrome and - planned percutaneous coronary intervention. As novel antiplatelet agents emerge - and existing agents are tested in different patient populations, the evaluation - of the relative economic efficiency of these oral antiplatelet treatment - strategies will continue to be instrumental to optimally inform clinical and - health-policy decision-making. -FAU - Arnold, Suzanne V -AU - Arnold SV -AD - Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO - 64111, USA. -FAU - Cohen, David J -AU - Cohen DJ -FAU - Magnuson, Elizabeth A -AU - Magnuson EA -LA - eng -PT - Journal Article -PT - Review -DEP - 20110809 -PL - England -TA - Nat Rev Cardiol -JT - Nature reviews. Cardiology -JID - 101500075 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Administration, Oral -MH - Cardiovascular Diseases/*drug therapy/*economics -MH - Cost-Benefit Analysis -MH - Drug Administration Schedule -MH - *Drug Costs -MH - Drug Therapy, Combination -MH - Humans -MH - Platelet Aggregation Inhibitors/*administration & dosage/*economics -MH - Preventive Health Services/economics -MH - Treatment Outcome -EDAT- 2011/08/10 06:00 -MHDA- 2012/01/21 06:00 -CRDT- 2011/08/10 06:00 -PHST- 2011/08/10 06:00 [entrez] -PHST- 2011/08/10 06:00 [pubmed] -PHST- 2012/01/21 06:00 [medline] -AID - nrcardio.2011.119 [pii] -AID - 10.1038/nrcardio.2011.119 [doi] -PST - epublish -SO - Nat Rev Cardiol. 2011 Aug 9;8(10):580-91. doi: 10.1038/nrcardio.2011.119. - -PMID- 16584961 -OWN - NLM -STAT- MEDLINE -DCOM- 20060523 -LR - 20060404 -IS - 0733-8627 (Print) -IS - 0733-8627 (Linking) -VI - 24 -IP - 2 -DP - 2006 May -TI - Cardiovascular emergencies in the elderly. -PG - 339-70, vi -AB - Already the major cause of mortality in the United States, cardio-vascular - emergencies will become increasingly prevalent in the future as the geriatric - population doubles. This article discusses five cardiovascular emergencies: acute - coronary syndrome, congestive heart failure, dysrythmias, aortic dissection, and - ruptured abdominal aortic aneurysm. The discussion focuses on the differences in - presentation, management, and outcomes that characterize each disease amongst the - elderly. As a rule, the elderly have significantly worse outcomes than younger - patients. -FAU - Gupta, Rohit -AU - Gupta R -AD - Department of Emergency Medicine, Advocate Christ Medical Center, 4440 West - 95(th) Street, Oak Lawn, IL 60453, USA. rogu@alum.mit.edu -FAU - Kaufman, Seth -AU - Kaufman S -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Emerg Med Clin North Am -JT - Emergency medicine clinics of North America -JID - 8219565 -SB - IM -MH - Aged -MH - Cardiovascular Diseases/*epidemiology/therapy -MH - Emergencies/*epidemiology -MH - Health Services for the Aged -MH - Humans -MH - Incidence -MH - United States/epidemiology -RF - 130 -EDAT- 2006/04/06 09:00 -MHDA- 2006/05/24 09:00 -CRDT- 2006/04/06 09:00 -PHST- 2006/04/06 09:00 [pubmed] -PHST- 2006/05/24 09:00 [medline] -PHST- 2006/04/06 09:00 [entrez] -AID - S0733-8627(06)00004-6 [pii] -AID - 10.1016/j.emc.2006.01.003 [doi] -PST - ppublish -SO - Emerg Med Clin North Am. 2006 May;24(2):339-70, vi. doi: - 10.1016/j.emc.2006.01.003. - -PMID- 18251377 -OWN - NLM -STAT- MEDLINE -DCOM- 20080305 -LR - 20080206 -IS - 0743-6661 (Print) -IS - 0743-6661 (Linking) -VI - 39 -IP - 3 -DP - 2007 -TI - Utilizing NT-proBNP in the selection of risks for life insurance. -PG - 182-91 -AB - Brain natriuretic peptide (BNP) is a counter-regulatory hormone produced mainly - by ventricular myocardium. Early research studies were performed to ascertain its - value in the diagnosis of congestive heart failure in acute care settings. - Subsequent studies have explored its utility in screening for asymptomatic left - ventricular dysfunction in the community, determining prognosis in coronary - artery disease, appropriate timing of surgery in valve disorders, and in - evaluating many other cardiac diseases. This review summarizes the current status - of medical literature, introduces a new test to the insurance industry. -FAU - Illango, Ramanathan K -AU - Illango RK -AD - RK Illango Consulting, Inc, Gaithersburg, MD 200882, USA. rk@rkillango.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Insur Med -JT - Journal of insurance medicine (New York, N.Y.) -JID - 8401468 -RN - 0 (Peptide Fragments) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -CIN - J Insur Med. 2007;39(3):150-2. PMID: 18251371 -CIN - J Insur Med. 2007;39(3):153-6. PMID: 18251372 -MH - Aged -MH - Aged, 80 and over -MH - Chronic Disease -MH - Female -MH - Humans -MH - *Insurance, Life -MH - Male -MH - Middle Aged -MH - Natriuretic Peptide, Brain/*analysis -MH - Peptide Fragments/*analysis -MH - Risk Adjustment/*methods -MH - United States -RF - 38 -EDAT- 2008/02/07 09:00 -MHDA- 2008/03/06 09:00 -CRDT- 2008/02/07 09:00 -PHST- 2008/02/07 09:00 [pubmed] -PHST- 2008/03/06 09:00 [medline] -PHST- 2008/02/07 09:00 [entrez] -PST - ppublish -SO - J Insur Med. 2007;39(3):182-91. - -PMID- 16776046 -OWN - NLM -STAT- MEDLINE -DCOM- 20060714 -LR - 20091021 -IS - 0030-6002 (Print) -IS - 0030-6002 (Linking) -VI - 147 -IP - 20 -DP - 2006 May 21 -TI - [New data in the diagnosis and treatment of stable angina pectoris]. -PG - 917-23 -AB - Stable angina pectoris is a manifestation of ischemic heart disease which - frequently leeds to acute coronary syndrome. The patient has a short effort or - stress situation induced retrosternal pain which is easing after the elimination - of its cause, or taking nitroglycerin. Several new data have appeared in the - literature about the pathogenesis and diagnosis of stable angina pectoris. Due to - the international guidelines using the new drugs and revascularisation - techniques, the primary and secondary prevention of stable angina pectoris was - improved. -FAU - Kárpáti, Pál -AU - Kárpáti P -AD - Fovárosi Szent István Kórház, I Belgyógyászat. karpati23@hotmail.com -LA - hun -PT - English Abstract -PT - Journal Article -PT - Review -TT - Ujabb adatok a stabil angina pectoris jobb megismeréséhez. -PL - Hungary -TA - Orv Hetil -JT - Orvosi hetilap -JID - 0376412 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Acute Disease -MH - Angina Pectoris/complications/*diagnosis/*drug - therapy/etiology/physiopathology/prevention & control -MH - Angina, Unstable/etiology -MH - Cardiovascular Agents/therapeutic use -MH - Humans -MH - Myocardial Ischemia/complications -MH - Syndrome -RF - 47 -EDAT- 2006/06/17 09:00 -MHDA- 2006/07/15 09:00 -CRDT- 2006/06/17 09:00 -PHST- 2006/06/17 09:00 [pubmed] -PHST- 2006/07/15 09:00 [medline] -PHST- 2006/06/17 09:00 [entrez] -PST - ppublish -SO - Orv Hetil. 2006 May 21;147(20):917-23. - -PMID- 17694284 -OWN - NLM -STAT- MEDLINE -DCOM- 20071130 -LR - 20070813 -IS - 0723-5003 (Print) -IS - 0723-5003 (Linking) -VI - 102 -IP - 8 -DP - 2007 Aug 15 -TI - [Update cardiology 2006/2007]. -PG - 647-58 -AB - This article reviews advances in cardiovascular medicine published last year. The - following issues are reported in detail: (1) risk factors and lifestyle, (2) - computed tomography in coronary artery disease, (3) revascularization in - cardiogenic shock, (4) long-term anticoagulation in venous thrombosis, (5) anemia - in heart failure, (6) optimism and cardiovascular death, (7) mortality after - drug-eluting stents, (8) diabetes and cardiovascular disease, (9) new guidelines - atrial fibrillation, (10) dopamine agonists and cardiac valve regurgitation, (11) - beta-blockers and hypertension, (12) angiotensin-converting enzyme inhibitors and - aortic rupture, (13) statin therapy, (14) adherence to pharmacotherapy. -FAU - Fries, Roland -AU - Fries R -AD - Gotthard-Schettler-Klinik (Kardiologie, Angiologie, Sportmedizin), Bad Schönborn. -FAU - Kilter, Heiko -AU - Kilter H -FAU - Laufs, Ulrich -AU - Laufs U -FAU - Mewis, Christian -AU - Mewis C -FAU - Scheller, Bruno -AU - Scheller B -FAU - Böhm, Michael -AU - Böhm M -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Aktuelle Kardiologie 2006/2007: Jahresrückblick und Ausblick. -PL - Germany -TA - Med Klin (Munich) -JT - Medizinische Klinik (Munich, Germany : 1983) -JID - 8303501 -SB - IM -MH - Cardiology/*trends -MH - Cardiovascular Diseases/etiology/mortality/*therapy -MH - *Diffusion of Innovation -MH - Forecasting -MH - Germany -MH - Humans -MH - Survival Analysis -RF - 47 -EDAT- 2007/08/19 09:00 -MHDA- 2007/12/06 09:00 -CRDT- 2007/08/19 09:00 -PHST- 2007/05/15 00:00 [received] -PHST- 2007/05/21 00:00 [accepted] -PHST- 2007/08/19 09:00 [pubmed] -PHST- 2007/12/06 09:00 [medline] -PHST- 2007/08/19 09:00 [entrez] -AID - 10.1007/s00063-007-1080-x [doi] -PST - ppublish -SO - Med Klin (Munich). 2007 Aug 15;102(8):647-58. doi: 10.1007/s00063-007-1080-x. - -PMID- 17462519 -OWN - NLM -STAT- MEDLINE -DCOM- 20070717 -LR - 20070427 -IS - 0749-0690 (Print) -IS - 0749-0690 (Linking) -VI - 23 -IP - 2 -DP - 2007 May -TI - Evaluation of the acutely dyspneic elderly patient. -PG - 307-25, vi -AB - Dyspnea is among the most frequent complaints in the elderly. The prevalence of - comorbid medical conditions and the physiologic changes of aging present - significant challenges in determining the cause. The initial approach to the - elderly dyspneic patient mandates consideration of a broad range of diagnoses. - Failure to diagnose life-threatening medical conditions presenting with dyspnea - such as pulmonary embolus, acute coronary syndromes, congestive heart failure, - asthma, obstructive pulmonary disease, pneumothorax, and pneumonia can lead - significant morbidity and mortality. This article focuses on the rapid assessment - and approach to the acutely dyspneic elderly patient. -FAU - Torres, Mercedes -AU - Torres M -AD - Department of Emergency Medicine, University of Maryland School of Medicine, 110 - South Paca Street, Sixth Floor, Suite 200, Baltimore, MD 21201, USA. -FAU - Moayedi, Siamak -AU - Moayedi S -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Geriatr Med -JT - Clinics in geriatric medicine -JID - 8603766 -SB - IM -MH - Acute Disease -MH - Aged -MH - Cardiovascular Diseases/*complications/diagnosis/therapy -MH - Dyspnea/*etiology -MH - Humans -MH - Lung Diseases/*complications/diagnosis/therapy -MH - Pneumothorax/*complications/diagnosis/therapy -RF - 40 -EDAT- 2007/04/28 09:00 -MHDA- 2007/07/18 09:00 -CRDT- 2007/04/28 09:00 -PHST- 2007/04/28 09:00 [pubmed] -PHST- 2007/07/18 09:00 [medline] -PHST- 2007/04/28 09:00 [entrez] -AID - S0749-0690(07)00008-0 [pii] -AID - 10.1016/j.cger.2007.01.007 [doi] -PST - ppublish -SO - Clin Geriatr Med. 2007 May;23(2):307-25, vi. doi: 10.1016/j.cger.2007.01.007. - -PMID- 25340229 -STAT- Publisher -PB - Royal College of Physicians (UK) -CTI - National Institute for Health and Care Excellence: Clinical Guidelines -DP - 2013 Nov -BTI - MI - Secondary Prevention: Secondary Prevention in Primary and Secondary Care for - Patients Following a Myocardial Infarction: Partial Update of NICE CG48 -AB - Myocardial infarction (MI) remains one of the most dramatic presentations of - coronary artery disease (CAD). Complete occlusion of the artery often produces - myocardial necrosis and the classical picture of a heart attack with severe chest - pain, electrocardiographic (ECG) changes of ST-segment elevation, and an elevated - concentration of myocardial specific proteins in the circulation. Such people are - described as having a ST-segment elevation myocardial infarction (STEMI). - Intermittent or partial occlusion produces similar, but often less severe - clinical features, although no or transient and undetected ST elevation. Such - cases are described as a non-ST segment elevation myocardial infarction (NSTEMI). - People who have suffered from either of these conditions are amenable to - treatment to reduce the risk of further MI or other manifestations of vascular - disease, secondary prevention. -CI - Copyright © 2013, National Clinical Guideline Centre. -CN - National Clinical Guideline Centre (UK) -LA - eng -PT - Practice Guideline -PT - Review -PT - Book -PL - London -EDAT- 2013/11/01 00:00 -CRDT- 2013/11/01 00:00 -AID - NBK247688 [bookaccession] - -PMID- 18238751 -OWN - NLM -STAT- MEDLINE -DCOM- 20080313 -LR - 20231024 -IS - 1934-2403 (Electronic) -IS - 1530-891X (Linking) -VI - 14 -IP - 1 -DP - 2008 Jan-Feb -TI - Postprandial dysmetabolism: the missing link between diabetes and cardiovascular - events? -PG - 112-24 -AB - OBJECTIVE: To investigate the association of postprandial dysmetabolism, ie, - hyperglycemia, and hyperlipidemia with myocardial disease in diabetic, - glucose-intolerant, and glucose-tolerant patients. METHODS: We performed a - MEDLINE search of the English-language literature published between January 1979 - and April 2007 for studies regarding postprandial dysmetabolism and heart - disease. RESULTS: Postprandial dysmetabolism is associated with increased - inflammation, endothelial dysfunction, decreased fibrinolysis, plaque - instability, and cardiac events. CONCLUSION: There is a direct and proportional - association between postprandial dysmetabolism and both coronary artery disease - and cardiac events. -FAU - Bell, David S H -AU - Bell DS -AD - Southside Endocrinology, Birmingham, Alabama 35205, USA. dshbell@yahoo.com -FAU - O'Keefe, James H -AU - O'Keefe JH -FAU - Jellinger, Paul -AU - Jellinger P -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Endocr Pract -JT - Endocrine practice : official journal of the American College of Endocrinology - and the American Association of Clinical Endocrinologists -JID - 9607439 -RN - 0 (Blood Glucose) -SB - IM -MH - Atherosclerosis/etiology/metabolism -MH - Blood Glucose/physiology -MH - Cardiovascular Diseases/*etiology/*metabolism -MH - Diabetes Complications/*metabolism -MH - Diabetes Mellitus/epidemiology/*metabolism -MH - Diabetic Angiopathies/etiology/*metabolism -MH - Humans -MH - Hyperglycemia/epidemiology/etiology/metabolism/therapy -MH - Hyperlipidemias/epidemiology/etiology/metabolism -MH - *Postprandial Period -RF - 92 -EDAT- 2008/02/02 09:00 -MHDA- 2008/03/14 09:00 -CRDT- 2008/02/02 09:00 -PHST- 2008/02/02 09:00 [pubmed] -PHST- 2008/03/14 09:00 [medline] -PHST- 2008/02/02 09:00 [entrez] -AID - S1530-891X(20)44672-5 [pii] -AID - 10.4158/EP.14.1.112 [doi] -PST - ppublish -SO - Endocr Pract. 2008 Jan-Feb;14(1):112-24. doi: 10.4158/EP.14.1.112. - -PMID- 24288612 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20131129 -LR - 20250608 -IS - 2090-2204 (Print) -IS - 2090-2212 (Electronic) -IS - 2090-2204 (Linking) -VI - 2013 -DP - 2013 -TI - Impact of endothelial microparticles on coagulation, inflammation, and - angiogenesis in age-related vascular diseases. -PG - 734509 -LID - 10.1155/2013/734509 [doi] -LID - 734509 -AB - Endothelial microparticles (EMPs) are complex vesicular structures that originate - from plasma membranes of activated or apoptotic endothelial cells. EMPs play a - significant role in vascular function by altering the processes of inflammation, - coagulation, and angiogenesis, and they are key players in the pathogenesis of - several vascular diseases. Circulating EMPs are increased in many age-related - vascular diseases such as coronary artery disease, peripheral vascular disease, - cerebral ischemia, and congestive heart failure. Their elevation in plasma has - been considered as both a biomarker and bioactive effector of vascular damage and - a target for vascular diseases. This review focuses on the pleiotropic roles of - EMPs and the mechanisms that trigger their formation, particularly the - involvement of decreased estrogen levels, thrombin, and PAI-1 as major factors - that induce EMPs in age-related vascular diseases. -FAU - Markiewicz, Margaret -AU - Markiewicz M -AD - Division of Rheumatology and Immunology, Medical University of South Carolina, - 114 Doughty Street, STB, Charleston, SC 29425, USA. -FAU - Richard, Erin -AU - Richard E -FAU - Marks, Natalia -AU - Marks N -FAU - Ludwicka-Bradley, Anna -AU - Ludwicka-Bradley A -LA - eng -GR - K01 AG031909/AG/NIA NIH HHS/United States -PT - Journal Article -PT - Review -DEP - 20131028 -PL - United States -TA - J Aging Res -JT - Journal of aging research -JID - 101543460 -PMC - PMC3830876 -EDAT- 2013/11/30 06:00 -MHDA- 2013/11/30 06:01 -PMCR- 2013/10/28 -CRDT- 2013/11/30 06:00 -PHST- 2013/04/01 00:00 [received] -PHST- 2013/09/04 00:00 [accepted] -PHST- 2013/11/30 06:00 [entrez] -PHST- 2013/11/30 06:00 [pubmed] -PHST- 2013/11/30 06:01 [medline] -PHST- 2013/10/28 00:00 [pmc-release] -AID - 10.1155/2013/734509 [doi] -PST - ppublish -SO - J Aging Res. 2013;2013:734509. doi: 10.1155/2013/734509. Epub 2013 Oct 28. - -PMID- 22727001 -OWN - NLM -STAT- MEDLINE -DCOM- 20130117 -LR - 20151119 -IS - 1557-9832 (Electronic) -IS - 0272-2712 (Linking) -VI - 32 -IP - 2 -DP - 2012 Jun -TI - Cardiovascular disease in India. -PG - 217-30 -LID - 10.1016/j.cll.2012.04.001 [doi] -AB - Cardiovascular disease (CVD) is one of the leading cause of mortality in India. - It is estimated that 23.6 million CVD cases will be reported in subjects younger - than 40 years of age by 2015, suggesting that young Indians are at higher cardiac - risk. Evaluation of biomarkers in acute coronary syndrome (ACS) and at various - stages of the disease such as inflammation, ischemia, and heart failure would - indeed help to assess cardiac risk in Indian subjects. Identification of newer - genetic markers through the candidate and/or genome-wide association approach - would prove to be beneficial in developing a diagnostic assay for screening young - asymptomatic Indian subjects. -FAU - Ashavaid, Tester F -AU - Ashavaid TF -AD - Department of Laboratory Medicine, P.D. Hinduja National Hospital and Medical - Research Center, Veer Savarkar Marg, Mahim, Mumbai, Maharashtra, India. - dr_tashavaid@hindujahospital.com -FAU - Ponde, Chandrashekhar K -AU - Ponde CK -FAU - Shah, Swarup -AU - Shah S -FAU - Jawanjal, Monika -AU - Jawanjal M -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Clin Lab Med -JT - Clinics in laboratory medicine -JID - 8100174 -RN - 0 (Biomarkers) -SB - IM -MH - Biomarkers/metabolism -MH - Cardiovascular Diseases/*epidemiology/metabolism -MH - Humans -MH - India/epidemiology -MH - Risk Factors -EDAT- 2012/06/26 06:00 -MHDA- 2013/01/18 06:00 -CRDT- 2012/06/26 06:00 -PHST- 2012/06/26 06:00 [entrez] -PHST- 2012/06/26 06:00 [pubmed] -PHST- 2013/01/18 06:00 [medline] -AID - S0272-2712(12)00027-3 [pii] -AID - 10.1016/j.cll.2012.04.001 [doi] -PST - ppublish -SO - Clin Lab Med. 2012 Jun;32(2):217-30. doi: 10.1016/j.cll.2012.04.001. - -PMID- 21881684 -OWN - NLM -STAT- MEDLINE -DCOM- 20111102 -LR - 20231106 -IS - 1995-1892 (Print) -IS - 1680-0745 (Electronic) -IS - 1015-9657 (Linking) -VI - 22 -IP - 4 -DP - 2011 Jul-Aug -TI - The state of heart disease in Sudan. -PG - 191-6 -LID - 10.5830/CVJA-2010-054 [doi] -AB - Cardiovascular disease (CVD) is the leading cause of mortality worldwide and an - important cause of disability. In Africa, the burden of CVD is increasing rapidly - and it is now a public health concern. Epidemiological data on diseases is scarce - and fragmented on the continent. AIM: To review available data on the - epidemiology and pattern of heart disease in Sudan. METHODS: Data were obtained - from the Sudan Household Survey (SHHS) 2006, annual health statistical reports of - the Sudan Federal Ministry of Health, the STEPS survey of chronic disease risk - factors in Sudan/Khartoum, and journal publications. RESULTS: The SHHS reported a - prevalence of 2.5% for heart disease. Hypertensive heart disease (HHD), rheumatic - heart disease (RHD), ischaemic heart disease (IHD) and cardiomyopathy constitute - more than 80% of CVD in Sudan. Hypertension (HTN) had a prevalence of 20.1 and - 20.4% in the SHHS and STEPS survey, respectively. There were poor control rates - and a high prevalence of target-organ damage in the local studies. RHD prevalence - data were available only for Khartoum state and the incidence has dropped from - 3/1 000 people in the 1980s to 0.3% in 2003. There were no data on any other - states. The coronary event rates in 1989 were 112/100 000 people, with a total - mortality of 36/100 000. Prevalence rates of low physical activity, obesity, HTN, - hypercholesterolaemia, diabetes and smoking were 86.8, 53.9, 23.6, 19.8, 19.2 and - 12%, respectively, in the STEPS survey. Peripartum cardiomyopathy occurs at a - rate of 1.5% of all deliveries. Congenital heart disease is prevalent in 0.2% of - children. CONCLUSION: Heart diseases are an important cause of morbidity and - mortality in Sudan. The tetrad of hypertension, RHD, IHD and cardiomyopathy - constitute the bulk of CVD. Hypertension is prevalent, with poor control rates. A - decline in rheumatic heart disease was seen in the capital state and no data were - available on other parts of the country. No recent data on IHD were available. - Peripartum cardiomyopathy and congenital heart disease occur at similar rates to - those in other African countries. -FAU - Suliman, A -AU - Suliman A -AD - Department of Medicine, University of Khartoum, Khartoum, Sudan. - sulima01@hotmail.com -LA - eng -PT - Journal Article -PT - Review -PL - South Africa -TA - Cardiovasc J Afr -JT - Cardiovascular journal of Africa -JID - 101313864 -SB - IM -MH - Cardiomyopathies/epidemiology -MH - Heart Defects, Congenital/epidemiology -MH - Heart Diseases/*epidemiology/mortality -MH - Humans -MH - Hypertension/epidemiology -MH - Myocardial Ischemia/epidemiology -MH - Prevalence -MH - Prognosis -MH - Rheumatic Heart Disease/epidemiology -MH - Risk Assessment -MH - Risk Factors -MH - Sudan/epidemiology -MH - Time Factors -PMC - PMC3721897 -EDAT- 2011/09/02 06:00 -MHDA- 2011/11/04 06:00 -PMCR- 2011/08/01 -CRDT- 2011/09/02 06:00 -PHST- 2010/03/29 00:00 [received] -PHST- 2010/07/01 00:00 [accepted] -PHST- 2011/09/02 06:00 [entrez] -PHST- 2011/09/02 06:00 [pubmed] -PHST- 2011/11/04 06:00 [medline] -PHST- 2011/08/01 00:00 [pmc-release] -AID - 10.5830/CVJA-2010-054 [doi] -PST - ppublish -SO - Cardiovasc J Afr. 2011 Jul-Aug;22(4):191-6. doi: 10.5830/CVJA-2010-054. - -PMID- 24192594 -OWN - NLM -STAT- MEDLINE -DCOM- 20131227 -LR - 20131106 -IS - 1541-8243 (Electronic) -IS - 0038-4348 (Linking) -VI - 106 -IP - 11 -DP - 2013 Nov -TI - Cardiovascular disease in pregnancy: (women's health series). -PG - 624-30 -LID - 10.1097/SMJ.0000000000000015 [doi] -AB - Cardiovascular disease is the leading cause of death generally and the most - common cause of death during pregnancy in industrialized countries. Improvement - in early diagnosis and treatment of congenital heart disease has increased the - number of women with such conditions reaching reproductive age. The growing - prevalence of diabetes, hypertension, obesity, hyperlipidemia, and metabolic - syndrome has concurrently added to the population of pregnant women with acquired - heart disease, including coronary artery disease. Physiologic changes occurring - during pregnancy can stress a compromised cardiovascular system, resulting in - maternal morbidity, mortality, and compromised fetal outcomes. These risks - complicate affected women's decisions to become pregnant, their ability to carry - a pregnancy to term, and the complexity and risk benefit of cardiovascular - treatments delivered during pregnancy. Risk assessment indices assist the - obstetrician, cardiologist, and primary care provider in determining the general - prognosis of the patient during pregnancy and although imperfect, can aid - patients in making informed decisions. Treatments must be selected that ideally - benefit the health of both mother and fetus and at a minimum limit risk to the - fetus during gestation. -FAU - Nickens, Myrna Alexander -AU - Nickens MA -AD - From the Division of Cardiovascular Diseases, Department of Medicine, University - of Mississippi Medical Center, Jackson, and the Department of Medicine, Quillen - College of Medicine, East Tennessee State University, Johnson City. -FAU - Long, Robert Craig -AU - Long RC -FAU - Geraci, Stephen A -AU - Geraci SA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - South Med J -JT - Southern medical journal -JID - 0404522 -SB - IM -MH - Adult -MH - Cardiomyopathies/complications -MH - Cardiovascular Diseases/complications -MH - Female -MH - Heart Diseases/complications -MH - Humans -MH - Hypertension, Pulmonary/complications -MH - Myocardial Infarction/complications -MH - Pregnancy/physiology -MH - Pregnancy Complications, - Cardiovascular/diagnosis/*etiology/physiopathology/therapy -MH - Risk Factors -MH - Young Adult -EDAT- 2013/11/07 06:00 -MHDA- 2013/12/29 06:00 -CRDT- 2013/11/07 06:00 -PHST- 2013/11/07 06:00 [entrez] -PHST- 2013/11/07 06:00 [pubmed] -PHST- 2013/12/29 06:00 [medline] -AID - 00007611-201311000-00008 [pii] -AID - 10.1097/SMJ.0000000000000015 [doi] -PST - ppublish -SO - South Med J. 2013 Nov;106(11):624-30. doi: 10.1097/SMJ.0000000000000015. - -PMID- 22261158 -OWN - NLM -STAT- MEDLINE -DCOM- 20120312 -LR - 20131121 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 59 -IP - 4 -DP - 2012 Jan 24 -TI - Imaging in the management of ischemic cardiomyopathy: special focus on magnetic - resonance. -PG - 359-70 -LID - 10.1016/j.jacc.2011.08.076 [doi] -AB - Heart failure of ischemic origin has become increasingly common over the last - decade because of the improved survival of patients with acute myocardial - infarction. Revascularization with coronary bypass grafting or percutaneous - coronary intervention plays a pivotal role in patients with ischemic - cardiomyopathy, although these interventions are often associated with relatively - high peri-procedural risk. The pathophysiological substrate of ischemic - cardiomyopathy is heterogeneous, varying from predominantly hibernating - myocardium to irreversible scarring. There is evidence to suggest that patients - with hibernating myocardium benefit most from revascularization, whereas medical - therapy is associated with an adverse prognosis. Therefore, noninvasive testing - is recommended by relevant guidelines to guide optimal management in these - patients. However, the role of noninvasive testing has recently been challenged. - There are various imaging modalities available that provide information on - different aspects of the disease, and therefore, they differ significantly in - sensitivity and specificity. In clinical practice, choosing among the different - imaging modalities can be difficult. Cardiac magnetic resonance has evolved into - a comprehensive modality that can accurately determine the amount of hibernating - myocardium as well as the presence and degree of myocardial ischemia and the - extent of the scar. This paper reviews the indications, accuracy, and clinical - utility of the available imaging techniques, with a special focus on cardiac - magnetic resonance in ischemic cardiomyopathy, and provides an outlook on how - this field might evolve in the future. -CI - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Schuster, Andreas -AU - Schuster A -AD - Division of Imaging Sciences and Biomedical Engineering, King's College London, - London, United Kingdom. -FAU - Morton, Geraint -AU - Morton G -FAU - Chiribiri, Amedeo -AU - Chiribiri A -FAU - Perera, Divaka -AU - Perera D -FAU - Vanoverschelde, Jean-Louis -AU - Vanoverschelde JL -FAU - Nagel, Eike -AU - Nagel E -LA - eng -GR - FS/10/029/28253/British Heart Foundation/United Kingdom -GR - RE/08/003/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Cardiomyopathies/*diagnosis/physiopathology -MH - Echocardiography -MH - Humans -MH - *Magnetic Resonance Imaging -MH - Multimodal Imaging -MH - Myocardial Ischemia/*diagnosis/physiopathology -MH - Positron-Emission Tomography -MH - Prognosis -MH - Tomography, X-Ray Computed -MH - Ventricular Function, Left -EDAT- 2012/01/21 06:00 -MHDA- 2012/03/13 06:00 -CRDT- 2012/01/21 06:00 -PHST- 2011/04/21 00:00 [received] -PHST- 2011/07/18 00:00 [revised] -PHST- 2011/08/02 00:00 [accepted] -PHST- 2012/01/21 06:00 [entrez] -PHST- 2012/01/21 06:00 [pubmed] -PHST- 2012/03/13 06:00 [medline] -AID - S0735-1097(11)04764-4 [pii] -AID - 10.1016/j.jacc.2011.08.076 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2012 Jan 24;59(4):359-70. doi: 10.1016/j.jacc.2011.08.076. - -PMID- 19725849 -OWN - NLM -STAT- MEDLINE -DCOM- 20100722 -LR - 20221207 -IS - 1540-8175 (Electronic) -IS - 0742-2822 (Linking) -VI - 27 -IP - 1 -DP - 2010 Jan -TI - Valvular heart disease in osteogenesis imperfecta: presentation of a case and - review of the literature. -PG - 69-73 -LID - 10.1111/j.1540-8175.2009.00973.x [doi] -AB - Osteogenesis imperfecta (OI) is a rare inheritable disorder of connective tissue. - While musculoskeletal abnormalities are well known, cardiovascular involvement is - rare. Aortic root dilation is the most common cardiovascular manifestation. OI - preferentially affects the left-sided heart valves, for unclear reasons, leading - to aortic and mitral regurgitation. Valve replacement surgery carries a unique - set of issues in this population, and fewer than 40 cases have been reported. We - report a case of chronic severe aortic regurgitation in a patient with OI - complicated by the development of a flail aortic valve leaflet and presenting - with a transient ischemic attack. The patient subsequently underwent successful - combined bioprosthetic aortic valve replacement and coronary artery bypass - grafting. We review the literature on valvular disease and other cardiovascular - manifestations in OI and the related surgical considerations relevant to this - patient population. -FAU - Bonita, Raphael E -AU - Bonita RE -AD - Division of Cardiology, Department of Medicine, Thomas Jefferson University - Hospital, Jefferson Medical College, Philadelphia, Pennsylvania, USA. -FAU - Cohen, Ira S -AU - Cohen IS -FAU - Berko, Barbara A -AU - Berko BA -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20090831 -PL - United States -TA - Echocardiography -JT - Echocardiography (Mount Kisco, N.Y.) -JID - 8511187 -SB - IM -MH - Cardiovascular Surgical Procedures/*methods -MH - Female -MH - Heart Valve Diseases/*diagnostic imaging/etiology/*surgery -MH - Humans -MH - Middle Aged -MH - Osteogenesis Imperfecta/complications/*diagnosis/*surgery -MH - Plastic Surgery Procedures/*methods -MH - Ultrasonography -RF - 41 -EDAT- 2009/09/04 06:00 -MHDA- 2010/07/23 06:00 -CRDT- 2009/09/04 06:00 -PHST- 2009/09/04 06:00 [entrez] -PHST- 2009/09/04 06:00 [pubmed] -PHST- 2010/07/23 06:00 [medline] -AID - ECHO973 [pii] -AID - 10.1111/j.1540-8175.2009.00973.x [doi] -PST - ppublish -SO - Echocardiography. 2010 Jan;27(1):69-73. doi: 10.1111/j.1540-8175.2009.00973.x. - Epub 2009 Aug 31. - -PMID- 19808434 -OWN - NLM -STAT- MEDLINE -DCOM- 20091027 -LR - 20091007 -IS - 1941-3084 (Electronic) -IS - 1941-3084 (Linking) -VI - 1 -IP - 5 -DP - 2008 Dec -TI - The left ventricular ostium: an anatomic concept relevant to idiopathic - ventricular arrhythmias. -PG - 396-404 -LID - 10.1161/CIRCEP.108.795948 [doi] -FAU - Yamada, Takumi -AU - Yamada T -AD - Division of Cardiovascular Disease and Department of Pathology, University of - Alabama at Birmingham, Birmingham, Alabama 35294-0019, USA. - takumi-y@fb4.so-net.ne.jp -FAU - Litovsky, Silvio H -AU - Litovsky SH -FAU - Kay, G Neal -AU - Kay GN -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Circ Arrhythm Electrophysiol -JT - Circulation. Arrhythmia and electrophysiology -JID - 101474365 -SB - IM -MH - Action Potentials -MH - Animals -MH - Arrhythmias, Cardiac/pathology/physiopathology/*surgery -MH - Cardiac Pacing, Artificial -MH - *Catheter Ablation/adverse effects -MH - Coronary Angiography -MH - Electrocardiography -MH - Electrophysiologic Techniques, Cardiac -MH - Heart Ventricles/pathology/physiopathology/surgery -MH - Humans -MH - Kinetics -MH - Treatment Outcome -RF - 30 -EDAT- 2009/10/08 06:00 -MHDA- 2009/10/29 06:00 -CRDT- 2009/10/08 06:00 -PHST- 2009/10/08 06:00 [entrez] -PHST- 2009/10/08 06:00 [pubmed] -PHST- 2009/10/29 06:00 [medline] -AID - 1/5/396 [pii] -AID - 10.1161/CIRCEP.108.795948 [doi] -PST - ppublish -SO - Circ Arrhythm Electrophysiol. 2008 Dec;1(5):396-404. doi: - 10.1161/CIRCEP.108.795948. - -PMID- 21410637 -OWN - NLM -STAT- MEDLINE -DCOM- 20120112 -LR - 20110919 -IS - 1533-2500 (Electronic) -IS - 1530-7085 (Linking) -VI - 11 -IP - 5 -DP - 2011 Sep-Oct -TI - 24. Chronic refractory angina pectoris. -PG - 476-82 -LID - 10.1111/j.1533-2500.2010.00444.x [doi] -AB - Angina pectoris, cardiac pain associated with ischemia, is considered refractory - when optimal anti-anginal therapy fails to resolve symptoms. It is associated - with a decreased life expectancy and diminishes the quality of life. Spinal cord - stimulation (SCS) may be considered for patients who have also undergone - comprehensive interventions, such as coronary artery bypass graft (CABG) and - percutaneous transluminal coronary angioplasty (PTCA) procedures. The mechanism - of action of SCS is not entirely clear. Pain reduction is related to the - increased release of inhibitory neuropeptides as well as normalization of the - intrinsic nerve system of the heart muscle, and may have a protective myocardial - effect. SCS in patients with refractory angina pectoris results in reduced - anginal attacks as well as improved rate pressure product prior to the occurrence - of ischemic events. This may be the result of reduced Myocardial Volume Oxygen - (MVO(2) ) and possibly the redistribution of the coronary blood flow to ischemic - areas. There are a number of studies that demonstrate that SCS does not mask - acute myocardial infarction. The efficacy of the treatment has been investigated - in two prospective, randomized studies. The long-term results showed an - improvement of the symptoms and of the quality of life. SCS can be an alternative - to surgical intervention in a selected patient population. In addition, SCS is a - viable option in patients in whom surgery is not possible. SCS is recommended in - patients with chronic refractory angina pectoris that does not respond to - conventional treatment and in whom revascularization procedures have been - attempted or not possible, and who are optimized from a medical perspective. -CI - © 2011 The Authors. Pain Practice © 2011 World Institute of Pain. -FAU - van Kleef, Maarten -AU - van Kleef M -AD - Department of Anesthesiology and Pain Management, Maastricht University Medical - Centre, Maastricht, the Netherlands. maarten.van.kleef@mumc.nl -FAU - Staats, Peter -AU - Staats P -FAU - Mekhail, Nagy -AU - Mekhail N -FAU - Huygen, Frank -AU - Huygen F -LA - eng -PT - Journal Article -PT - Review -DEP - 20110316 -PL - United States -TA - Pain Pract -JT - Pain practice : the official journal of World Institute of Pain -JID - 101130835 -SB - IM -CIN - Pain Pract. 2011 Nov-Dec;11(6):582. doi: 10.1111/j.1533-2500.2011.00502.x. PMID: - 22060309 -MH - Algorithms -MH - Angina Pectoris/diagnosis/*therapy -MH - Chronic Disease -MH - Diagnosis, Differential -MH - Drug Resistance -MH - Electric Stimulation Therapy -MH - Evidence-Based Medicine -MH - Humans -MH - Pain/etiology -MH - Pain Management/*methods -MH - Physical Examination -MH - Spinal Cord -EDAT- 2011/03/18 06:00 -MHDA- 2012/01/13 06:00 -CRDT- 2011/03/18 06:00 -PHST- 2011/03/18 06:00 [entrez] -PHST- 2011/03/18 06:00 [pubmed] -PHST- 2012/01/13 06:00 [medline] -AID - 10.1111/j.1533-2500.2010.00444.x [doi] -PST - ppublish -SO - Pain Pract. 2011 Sep-Oct;11(5):476-82. doi: 10.1111/j.1533-2500.2010.00444.x. - Epub 2011 Mar 16. - -PMID- 22297544 -OWN - NLM -STAT- MEDLINE -DCOM- 20121017 -LR - 20250306 -IS - 1573-6830 (Electronic) -IS - 0272-4340 (Print) -IS - 0272-4340 (Linking) -VI - 32 -IP - 5 -DP - 2012 Jul -TI - Stress cardiomyopathy: a syndrome of catecholamine-mediated myocardial stunning? -PG - 847-57 -LID - 10.1007/s10571-012-9804-8 [doi] -AB - During the past few years, a novel syndrome of heart failure and transient left - ventricular systolic dysfunction precipitated by acute emotional or physical - stress has been described. While patients with "stress cardiomyopathy"(SCM) - typically present with signs and symptoms that resemble an acute coronary - syndrome, it has become clear that this syndrome has unique clinical features - that can readily be distinguished from acute infarction.In particular, in - contrast to the irreversible myocardial injury seen with infarction, the - myocardial dysfunction of SCM is completely reversible and occurs in the absence - of plaque rupture and coronary thrombosis. There is increasing evidence that - exaggerated sympathetic stimulation may play a pathogenic role in the development - of SCM. Plasma catecholamine levels have been found to be markedly elevated in - some patients with SCM, and the syndrome has been observed in other clinical - states of catecholamine excess such as central neurologic injury and - pheochromocytoma.Further, intravenous catecholamines can precipitate SCM in - humans and can reproduce the syndrome in animal models. The precise mechanism in - which excessive sympathetic stimulation may result in transient left ventricular - dysfunction remains controversial. Abnormal myocardial blood flow due to - sympathetically mediated microvascular dysfunction has been suggested and is - supported by decreased coronary flow reserve during the acute phase of this - syndrome. An alternative explanation is the direct effect of catecholamines on - cardiac myocytes, possibly through cyclic AMP-mediated calcium overload. This - manuscript will review the clinical and diagnostic features of SCM and will - summarize the evidence supporting a sympathetically mediated pathogenesis. - Clinical risk factors that appear to increase susceptibility to SCM, possibly by - modulating myocyte and microvascular sensitivity to catecholamines, will also be - highlighted. -FAU - Wittstein, Ilan S -AU - Wittstein IS -AD - Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, - MD 21287, USA. iwittste@jhmi.edu -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cell Mol Neurobiol -JT - Cellular and molecular neurobiology -JID - 8200709 -RN - 0 (Catecholamines) -SB - IM -MH - Animals -MH - Catecholamines/*metabolism -MH - Genetic Predisposition to Disease -MH - Humans -MH - Models, Cardiovascular -MH - Myocardial Stunning/*complications/physiopathology -MH - Syndrome -MH - Takotsubo Cardiomyopathy/diagnosis/*etiology/physiopathology/therapy -PMC - PMC11498407 -EDAT- 2012/02/03 06:00 -MHDA- 2012/10/18 06:00 -PMCR- 2012/02/02 -CRDT- 2012/02/03 06:00 -PHST- 2011/10/31 00:00 [received] -PHST- 2012/01/16 00:00 [accepted] -PHST- 2012/02/03 06:00 [entrez] -PHST- 2012/02/03 06:00 [pubmed] -PHST- 2012/10/18 06:00 [medline] -PHST- 2012/02/02 00:00 [pmc-release] -AID - 9804 [pii] -AID - 10.1007/s10571-012-9804-8 [doi] -PST - ppublish -SO - Cell Mol Neurobiol. 2012 Jul;32(5):847-57. doi: 10.1007/s10571-012-9804-8. - -PMID- 18672577 -OWN - NLM -STAT- MEDLINE -DCOM- 20080912 -LR - 20080804 -IS - 0042-773X (Print) -IS - 0042-773X (Linking) -VI - 54 -IP - 6 -DP - 2008 Jun -TI - [The risk of cardiovascular diseases induced by radiotherapy]. -PG - 646-52 -AB - At present the number of cancer survivors is still increasing. However, their - long-term quality of life after anticancer treatment can be decreased. - Radiotherapy may represent a risk for the future of some oncologic patients. The - late cardiovascular effects of radiotherapy to the area of thorax, cranium and to - the abdominal area are the actual multidisciplinary problem. The unique problem - is mediastinal radiotherapy which may induce the development of the - cardiomyopathy, constrictive pericarditis, coronary artery disease, myocardial - infarction, valvular defects, arrhythmias and other complications. Exact - knowledge of pathophysiological mechanisms of radiation induced cardiovascular - damage after radiotherapy as well as using of new diagnostic cardiologic methods - might be useful for the detection of subclinical abnormalities and their early - treatment already in the asymptomatic patients. -FAU - Hudecová, K -AU - Hudecová K -AD - Ustav patologickej fyziológie, Oddelenie klinickej patofyziológie Lekárskej - fakulty UK Bratislava, Slovenská republika. kristina.hudecova@fmed.uniba.sk -FAU - Urbanová, D -AU - Urbanová D -FAU - Petrásová, H -AU - Petrásová H -LA - slo -PT - English Abstract -PT - Journal Article -PT - Review -TT - Riziko vzniku kardiovaskulárnych ochorení v súvislosti s rádioterapiou. -PL - Czech Republic -TA - Vnitr Lek -JT - Vnitrni lekarstvi -JID - 0413602 -SB - IM -MH - Heart/radiation effects -MH - Heart Diseases/*etiology -MH - Humans -MH - Mediastinum/radiation effects -MH - *Radiation Injuries -MH - Radiography, Thoracic/*adverse effects -MH - Thoracic Neoplasms/*radiotherapy -RF - 50 -EDAT- 2008/08/05 09:00 -MHDA- 2008/09/16 09:00 -CRDT- 2008/08/05 09:00 -PHST- 2008/08/05 09:00 [pubmed] -PHST- 2008/09/16 09:00 [medline] -PHST- 2008/08/05 09:00 [entrez] -PST - ppublish -SO - Vnitr Lek. 2008 Jun;54(6):646-52. - -PMID- 24227810 -OWN - NLM -STAT- MEDLINE -DCOM- 20141028 -LR - 20240502 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Print) -IS - 0195-668X (Linking) -VI - 35 -IP - 7 -DP - 2014 Feb -TI - Natriuretic peptides in cardiovascular diseases: current use and perspectives. -PG - 419-25 -LID - 10.1093/eurheartj/eht466 [doi] -AB - The natriuretic peptides (NPs) family, including atrial, B-type, and C-type NPs, - is a group of hormones possessing relevant haemodynamic and anti-remodelling - actions in the cardiovascular (CV) system. Due to their diuretic, natriuretic, - vasorelaxant, anti-proliferative, and anti-hypertrophic effects, they are - involved in the pathogenic mechanisms leading to major CV diseases, such as heart - failure (HF), coronary artery disease, hypertension and left ventricular - hypertrophy, and cerebrovascular accidents. Blood levels of NPs have established - predictive value in the diagnosis of HF, as well as for its prognostic - stratification. In addition, they provide useful clinical information in - hypertension and in both stable and unstable coronary artery disease. Structural - abnormalities of atrial natriuretic peptide gene (NPPA), as well as genetically - induced changes in circulating levels of NPs, have a pathogenic causal link with - CV diseases and represent emerging markers of CV risk. Novel NP-based therapeutic - strategies are currently under advanced clinical development, as they are - expected to contribute to the future management of hypertension and HF. The - present review provides a current appraisal of NPs' clinical implications and a - critical perspective of the potential therapeutic impact of pharmacological - manipulation of this class of CV hormones. -FAU - Volpe, Massimo -AU - Volpe M -AD - Department of Clinical and Molecular Medicine, School of Medicine and Psychology, - Sapienza University of Rome, Ospedale S. Andrea, Rome, Italy. -FAU - Rubattu, Speranza -AU - Rubattu S -FAU - Burnett, John Jr -AU - Burnett J Jr -LA - eng -GR - R01 HL036634/HL/NHLBI NIH HHS/United States -GR - R01 HL083231/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131113 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (Natriuretic Peptides) -SB - IM -MH - Cardiovascular Diseases/*diagnosis -MH - Humans -MH - Natriuretic Peptides/blood/*physiology/therapeutic use -MH - Practice Guidelines as Topic -MH - Prognosis -MH - Renin-Angiotensin System/physiology -MH - Risk Assessment -PMC - PMC4023301 -OTO - NOTNLM -OT - ARNi -OT - Cardiovascular diseases -OT - Genetics -OT - NEP inhibitors -OT - Natriuretic peptides -OT - Natriuretic peptides analogues -EDAT- 2013/11/15 06:00 -MHDA- 2014/10/29 06:00 -PMCR- 2015/02/14 -CRDT- 2013/11/15 06:00 -PHST- 2013/11/15 06:00 [entrez] -PHST- 2013/11/15 06:00 [pubmed] -PHST- 2014/10/29 06:00 [medline] -PHST- 2015/02/14 00:00 [pmc-release] -AID - eht466 [pii] -AID - 10.1093/eurheartj/eht466 [doi] -PST - ppublish -SO - Eur Heart J. 2014 Feb;35(7):419-25. doi: 10.1093/eurheartj/eht466. Epub 2013 Nov - 13. - -PMID- 23445870 -OWN - NLM -STAT- MEDLINE -DCOM- 20140107 -LR - 20130404 -IS - 1423-0143 (Electronic) -IS - 1420-4096 (Linking) -VI - 37 -IP - 1 -DP - 2013 -TI - An exceptional cause of progressive dyspnoea in a renal transplant recipient: - hemangioma of the mitral valve. -PG - 9-14 -LID - 10.1159/000343395 [doi] -AB - Primary cardiac hemangioma is a very rare benign vascular tumor, with valvular - hemangiomas being even less frequent as valves are generally avascular - structures. We present the first case of mitral valve hemangioma in a renal - transplant recipient. Patient presented with progressive dyspnea. Transesophageal - echocardiogram (TEE) demonstrated a 0.8x0.9-cm pedunculated tumor mass on the - posterior leaflet of the mitral valve. Coronary angiography identified a small - artery which filled from the circumflex artery and fed the tumor. The tumor was - surgically removed. Histopathological examination revealed a hemangioma. The - postoperative course was uneventful with stable graft function. -CI - Copyright © 2013 S. Karger AG, Basel. -FAU - Juric, Ivana -AU - Juric I -AD - Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, - University Hospital Centre Zagreb, and School of Medicine, University of Zagreb, - Zagreb, Croatia. -FAU - Hadzibegovic, Irzal -AU - Hadzibegovic I -FAU - Kes, Petar -AU - Kes P -FAU - Biocina, Bojan -AU - Biocina B -FAU - Milicic, Davor -AU - Milicic D -FAU - Basic-Jukic, Nikolina -AU - Basic-Jukic N -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20130226 -PL - Switzerland -TA - Kidney Blood Press Res -JT - Kidney & blood pressure research -JID - 9610505 -SB - IM -MH - Disease Progression -MH - Dyspnea/*diagnosis/etiology -MH - Female -MH - Heart Neoplasms/complications/*diagnosis -MH - Hemangioma/complications/*diagnosis -MH - Humans -MH - Kidney Transplantation/*adverse effects -MH - Middle Aged -MH - Mitral Valve/*pathology -MH - Postoperative Complications/*diagnosis/etiology -EDAT- 2013/03/01 06:00 -MHDA- 2014/01/08 06:00 -CRDT- 2013/03/01 06:00 -PHST- 2012/12/04 00:00 [accepted] -PHST- 2013/03/01 06:00 [entrez] -PHST- 2013/03/01 06:00 [pubmed] -PHST- 2014/01/08 06:00 [medline] -AID - 000343395 [pii] -AID - 10.1159/000343395 [doi] -PST - ppublish -SO - Kidney Blood Press Res. 2013;37(1):9-14. doi: 10.1159/000343395. Epub 2013 Feb - 26. - -PMID- 22863509 -OWN - NLM -STAT- MEDLINE -DCOM- 20121231 -LR - 20161125 -IS - 1646-0758 (Electronic) -IS - 0870-399X (Linking) -VI - 24 Suppl 4 -DP - 2011 Dec -TI - [Myocardial viability assessment]. -PG - 989-94 -AB - The prognosis for patients with chronic coronary artery disease and severe left - ventricular dysfunction is poor, despite advances in different therapies. The - assessment of myocardial viability has become an important aspect of the - diagnosis, prognosis and management of patients with ischemic cardiomyopathy. - Patients with left ventricular dysfunction, with a substantial amount of severely - ischemic myocardium are at highest risk, and are likely to benefit from coronary - revascularization. Patients with predominantly scar tissue should be treated - medically. Multiple imaging techniques have been developed to assess viable and - nonviable myocardium by evaluating perfusion, cell membrane integrity, glucose - metabolism, fibrosis and contractile reserve. PET FDG-F18, myocardial perfusion - scintigraphy (with (201)Tl and (99m)Tc), dobutamine stress echocardiography and - more recently magnetic resonance have been extensively evaluated for assessment - of viability and prediction of clinical outcome after coronary revascularization. - In general, nuclear imaging techniques have a higher sensitivity for the - detection of viability, whereas techniques evaluating contractile reserve have - higher specificity (with lower sensitivity). Magnetic resonance has a high - diagnostic accuracy for assessment of the transmural extent of myocardial scar - tissue. The aim of this article is to review the role of Nuclear Medicine in - assessing myocardial viability and risk stratification in patients with advanced - left ventricular dysfunction, and to compare it with other imaging modalities. -FAU - Fernandes, Hélder -AU - Fernandes H -AD - Serviços de Medicina Nuclear, Cardiologia e de Radiologia, Hospital S João, - Porto, Portugal. -FAU - Sousa, Alexandra -AU - Sousa A -FAU - Campos, José -AU - Campos J -FAU - Patrício, José -AU - Patrício J -FAU - Oliveira, Patrícia -AU - Oliveira P -FAU - Vieira, Tiago -AU - Vieira T -FAU - Oliveira, Ana -AU - Oliveira A -FAU - Faria, Teresa -AU - Faria T -FAU - Perez, Berta -AU - Perez B -FAU - Martins, Elisabete -AU - Martins E -FAU - Pereira, Jorge -AU - Pereira J -LA - por -PT - Journal Article -PT - Review -TT - Avaliação da viabilidade miocárdica. -DEP - 20111231 -PL - Portugal -TA - Acta Med Port -JT - Acta medica portuguesa -JID - 7906803 -SB - IM -MH - Heart Function Tests -MH - Humans -MH - Radionuclide Imaging -MH - Risk Assessment -MH - Ventricular Dysfunction, Left/diagnosis/*diagnostic imaging -EDAT- 2012/08/17 06:00 -MHDA- 2013/01/01 06:00 -CRDT- 2012/08/07 06:00 -PHST- 2012/08/07 06:00 [entrez] -PHST- 2012/08/17 06:00 [pubmed] -PHST- 2013/01/01 06:00 [medline] -PST - ppublish -SO - Acta Med Port. 2011 Dec;24 Suppl 4:989-94. Epub 2011 Dec 31. - -PMID- 20532458 -OWN - NLM -STAT- MEDLINE -DCOM- 20100928 -LR - 20211020 -IS - 1995-1892 (Print) -IS - 1680-0745 (Electronic) -IS - 1015-9657 (Linking) -VI - 21 -IP - 3 -DP - 2010 May-Jun -TI - Persistent left superior vena cava with absent right superior vena cava: a case - report and review of the literature. -PG - 164-6 -AB - We report on a rare case of persistent left superior vena cava (PLSVC) with - absent right superior vena cava (RSVC), an anomaly that is also known as isolated - PLSVC. This venous malformation was identified incidentally in a 30-year-old - woman during thoracic multi-detector computed tomography (MDCT), which was - performed with the suspicion of intra-thoracic malignancy. On thoracic MDCT, the - RSVC was absent. A bridging vein drained the right jugular and right subclavian - veins and joined the left brachiocephalic vein in order to form the PLSVC, which - descended on the left side of the mediastinum and drained into the right atrium - (RA) via a dilated coronary sinus (CS). The patient was referred to the - cardiology department for further evaluation. Transthoracic echocardiography - revealed a dilated CS, and agitated saline injected from the left or right arms - revealed opacification of the CS before the RA. The patient had no additional - cardiac abnormality. Isolated PLSVC is usually asymptomatic but it can pose - difficulties with central venous access, pacemaker implantation and - cardiothoracic surgery. This condition is also associated with an increased - incidence of congenital heart disease, arrhythmias and conduction disturbances. A - wide spectrum of clinicians should be aware of this anomaly, its variations and - possible complications. -FAU - Uçar, O -AU - Uçar O -AD - Department of Cardiology, Ankara Numune Education and Research Hospital, Sihhiye, - Ankara, Turkey. ozgul_ucar@hotmail.com -FAU - Paşaoğlu, L -AU - Paşaoğlu L -FAU - Ciçekçioğlu, H -AU - Ciçekçioğlu H -FAU - Vural, M -AU - Vural M -FAU - Kocaoğlu, I -AU - Kocaoğlu I -FAU - Aydoğdu, S -AU - Aydoğdu S -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - South Africa -TA - Cardiovasc J Afr -JT - Cardiovascular journal of Africa -JID - 101313864 -SB - IM -MH - Adult -MH - Coronary Sinus/diagnostic imaging -MH - Dilatation, Pathologic -MH - Echocardiography -MH - Female -MH - Humans -MH - Incidental Findings -MH - Tomography, X-Ray Computed -MH - Vascular Malformations/*diagnosis/diagnostic imaging -MH - Vena Cava, Superior/*abnormalities/diagnostic imaging -PMC - PMC5592325 -EDAT- 2010/06/10 06:00 -MHDA- 2010/09/30 06:00 -PMCR- 2010/06/01 -CRDT- 2010/06/10 06:00 -PHST- 2010/06/10 06:00 [entrez] -PHST- 2010/06/10 06:00 [pubmed] -PHST- 2010/09/30 06:00 [medline] -PHST- 2010/06/01 00:00 [pmc-release] -PST - ppublish -SO - Cardiovasc J Afr. 2010 May-Jun;21(3):164-6. - -PMID- 22772919 -OWN - NLM -STAT- MEDLINE -DCOM- 20130319 -LR - 20211021 -IS - 1993-0402 (Electronic) -IS - 1672-0415 (Linking) -VI - 18 -IP - 7 -DP - 2012 Jul -TI - Roles and mechanisms of ginseng in protecting heart. -PG - 548-55 -LID - 10.1007/s11655-012-1148-1 [doi] -AB - Ginseng, the root of Panax ginseng C. A. Mayer, has long been used clinically in - China to treat various diseases. Multiple effects of ginseng, such as antitumor, - antiinflammatory, antiallergic, antioxidative, antidiabetic and antihypertensive - have been confirmed by modern medicine. Recently, the clinical utilization of - ginseng to treat heart diseases has increased dramatically. The roles of ginseng - in protecting heart are foci for research in modern medical science and have been - partially demonstrated, and the mechanisms of protection against coronary artery - disease, cardiac hypertrophy, heart failure, cardiac energy metabolism, cardiac - contractility, and arrhythmia are being uncovered progressively. However, more - studies are needed to elucidate the complex mechanisms by which ginseng protects - heart. All such studies will provide evidence of ginseng's clinical application, - international promotion, and new drug development. -FAU - Zheng, Si-Dao -AU - Zheng SD -AD - Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing - 100039, China. whjyuanzhang@yahoo.com.cn -FAU - Wu, Hong-Jin -AU - Wu HJ -FAU - Wu, De-Lin -AU - Wu DL -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120707 -PL - China -TA - Chin J Integr Med -JT - Chinese journal of integrative medicine -JID - 101181180 -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Animals -MH - Cardiotonic Agents/chemistry/*pharmacology -MH - Energy Metabolism/drug effects -MH - Heart/*drug effects/physiopathology -MH - Humans -MH - Myocardial Contraction/drug effects -MH - Panax/*chemistry -EDAT- 2012/07/10 06:00 -MHDA- 2013/03/21 06:00 -CRDT- 2012/07/10 06:00 -PHST- 2011/12/28 00:00 [received] -PHST- 2012/07/10 06:00 [entrez] -PHST- 2012/07/10 06:00 [pubmed] -PHST- 2013/03/21 06:00 [medline] -AID - 10.1007/s11655-012-1148-1 [doi] -PST - ppublish -SO - Chin J Integr Med. 2012 Jul;18(7):548-55. doi: 10.1007/s11655-012-1148-1. Epub - 2012 Jul 7. - -PMID- 22724410 -OWN - NLM -STAT- MEDLINE -DCOM- 20130425 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 18 -IP - 33 -DP - 2012 -TI - Clinical use of aspirin in ischemic heart disease: past, present and future. -PG - 5215-23 -AB - Aspirin is an antiplatelet drug, inhibiting the cyclooxygenase activity of - platelet prostaglandin H synthase-1 and almost complete suppressing platelet - capacity to generate the prothrombotic and proatherogenic thromboxane A2. - Antiplatelet therapy with aspirin reduces the risk of serious vascular events by - about a quarter in patients who are at high risk because they already have - occlusive vascular disease. However, the inhibition of thromboxane-dependent - platelet function by aspirin is effective for the prevention of thrombosis, but - is also associated with excess bleeding, although the absolute increase in major - gastrointestinal or other major extracranial bleeds is an order of magnitude - smaller. For secondary prevention of vascular events, the benefits of aspirin - therapy substantially exceed the risks. Therefore, aspirin is a cornerstone of - antithrombotic therapy in acute coronary syndromes, in chronic ischemic heart - disease and in percutaneous coronary intervention. On the other hand, the role of - aspirin in primary prevention remains uncertain and it is still debated, because - the absolute risk of vascular complications is the major determinant of the - absolute benefit of antiplatelet prophylaxis and the reduction in vascular events - needs to be weighed against any increase in major bleeds. Future data from - ongoing studies will help us to identify people at high vascular risk who take - advantage from aspirin therapy for primary prevention or will indicate if - specific category of high risk patients, like patients with diabetes, could be - better protected from an increase in the frequency of aspirin administration. -FAU - De Caterina, Raffaele -AU - De Caterina R -AD - Institute of Cardiology, "G. d'Annunzio" University - Chieti, C/o Ospedale SS. - Annunziata, Via dei Vestini, 66013 Chieti, Italy. rdecater@unich.it -FAU - Renda, Giulia -AU - Renda G -LA - eng -PT - Historical Article -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Cyclooxygenase Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 57576-52-0 (Thromboxane A2) -RN - EC 1.14.99.1 (Cyclooxygenase 1) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Animals -MH - Aspirin/adverse effects/history/*therapeutic use -MH - Blood Platelets/*drug effects/metabolism -MH - Cyclooxygenase 1/blood -MH - Cyclooxygenase Inhibitors/adverse effects/history/*therapeutic use -MH - Hemorrhage/chemically induced -MH - History, 20th Century -MH - History, 21st Century -MH - Humans -MH - Myocardial Ischemia/blood/*drug therapy -MH - Patient Selection -MH - Platelet Aggregation Inhibitors/adverse effects/history/*therapeutic use -MH - *Primary Prevention/history/trends -MH - Risk Factors -MH - *Secondary Prevention/history/trends -MH - Thromboxane A2/blood -MH - Treatment Outcome -EDAT- 2012/06/26 06:00 -MHDA- 2013/04/26 06:00 -CRDT- 2012/06/26 06:00 -PHST- 2012/04/16 00:00 [received] -PHST- 2012/04/26 00:00 [accepted] -PHST- 2012/06/26 06:00 [entrez] -PHST- 2012/06/26 06:00 [pubmed] -PHST- 2013/04/26 06:00 [medline] -AID - CPD-EPUB-20120619-3 [pii] -AID - 10.2174/138161212803251943 [doi] -PST - ppublish -SO - Curr Pharm Des. 2012;18(33):5215-23. doi: 10.2174/138161212803251943. - -PMID- 21774782 -OWN - NLM -STAT- MEDLINE -DCOM- 20120514 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 17 -IP - 21 -DP - 2011 -TI - Tocotrienols and cardiovascular health. -PG - 2147-54 -AB - This review emphasizes the effects of tocotrienols on the risk factors for - atherosclerosis, plaque instability and thrombogenesis, and compares these - effects with tocopherol. Tocotrienols reduce serum lipids and raise serum HDL-C. - Alpha-tocopherol, on the other hand, has no effect on serum lipids. Tocotrienols - have greater antioxidant activity than tocopherols. Both reduce the serum levels - of C-reactive protein (CRP) and advanced glycation end products, and expression - of cell adhesion molecules. The CRP-lowering effects of tocotrienols are greater - than tocopherol. Tocotrienols reduce inflammatory mediators, δ-tocotrienol being - more potent, followed by γ- and α-tocotrienol. Tocotrienols are antithrombotic - and suppress the expression of matrix metalloproteinases. They suppress, regress - and slow the progression of atherosclerosis, while tocopherol only suppresses, - and has no effect on regression and slowing of progression of atherosclerosis. - Tocotrienol reduces risk factors for destabilization of atherosclerotic plaques. - There are no firm data to suggest that tocotrienols are effective in reducing the - risk of cardiac events in established ischemic heart disease. Alpha-tocopherol is - effective in primary prevention of coronary artery disease (CAD), but has no - conclusive evidence that it has beneficial effects in patients with established - ischemic heart disease. Tocotrienols are effective in reducing - ischemia-reperfusion cardiac injury in experimental animals and has the potential - to be used in patients undergoing angioplasty, stent implantation and - aorto-coronary bypass surgery. In conclusion, experimental data suggest that - tocotrienols have a potential for cardiovascular health, but long-term randomized - clinical trials are needed to establish their efficacy in primary and secondary - prevention of CAD. -FAU - Prasad, Kailash -AU - Prasad K -AD - Department of Physiology, College of Medicine, University of Saskatchewan, 107 - Wiggins Road, Saskatoon SK S7N 5E5, Canada. k.prasad@usask.ca -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Antioxidants) -RN - 0 (Cholesterol, HDL) -RN - 0 (Glycation End Products, Advanced) -RN - 0 (Tocotrienols) -RN - 9007-41-4 (C-Reactive Protein) -RN - R0ZB2556P8 (Tocopherols) -SB - IM -MH - Animals -MH - Antioxidants/administration & dosage/adverse effects/pharmacology/*therapeutic - use -MH - C-Reactive Protein/metabolism -MH - Cardiovascular Diseases/blood/metabolism/*prevention & control -MH - Cholesterol, HDL/blood -MH - Glycation End Products, Advanced/blood -MH - Humans -MH - Primary Prevention -MH - Risk Factors -MH - Secondary Prevention -MH - Tocopherols/administration & dosage/adverse effects/pharmacology/*therapeutic use -MH - Tocotrienols/administration & dosage/adverse effects/pharmacology/*therapeutic - use -EDAT- 2011/07/22 06:00 -MHDA- 2012/05/15 06:00 -CRDT- 2011/07/22 06:00 -PHST- 2011/06/02 00:00 [received] -PHST- 2011/06/21 00:00 [accepted] -PHST- 2011/07/22 06:00 [entrez] -PHST- 2011/07/22 06:00 [pubmed] -PHST- 2012/05/15 06:00 [medline] -AID - BSP/CPD/E-Pub/000534 [pii] -AID - 10.2174/138161211796957418 [doi] -PST - ppublish -SO - Curr Pharm Des. 2011;17(21):2147-54. doi: 10.2174/138161211796957418. - -PMID- 18923235 -OWN - NLM -STAT- MEDLINE -DCOM- 20081230 -LR - 20181201 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 16 -IP - 6 -DP - 2008 Nov-Dec -TI - Prasugrel: a new antiplatelet drug for the prevention and treatment of - cardiovascular disease. -PG - 314-8 -LID - 10.1097/CRD.0b013e318189a701 [doi] -AB - Prasugrel, trade name Effient, is an investigational new antiplatelet drug - currently under review for clinical use by the Food and Drug Administration. It - is a thienopyridine analog with a structure similar to that of clopidogrel and - ticlopidine. Thienopyridine derivatives inhibit platelet aggregation induced by - adenosine diphosphate by irreversibly inhibiting the binding of adenosine - diphosphate to the purinergic P2Y12 receptor on the platelet surface. Prasugrel - has been shown to be a potent antiplatelet agent with a faster, more consistent, - and greater inhibition of platelet aggregation compared with clopidogrel. It is - debatable, however, how effectively these pharmacologic benefits will translate - to clinical benefits. The results of the large TRITON-TIMI 38 trial, which - compared prasugrel and clopidogrel in patients with acute coronary syndrome who - were scheduled to receive coronary stents, demonstrated a significant reduction - in ischemic events, including stent thrombosis, with prasugrel, but with an - increased risk of major bleeding. The exact role of prasugrel in the management - of ischemic heart disease is still being defined, but the risk:benefit ratio will - likely play a major role in directing the best place for therapy with this new - agent. -FAU - Koo, Michael H -AU - Koo MH -AD - Departments of Medicine, Stony Brook University Medical Center, Stony Brook, New - York, USA. -FAU - Nawarskas, James J -AU - Nawarskas JJ -FAU - Frishman, William H -AU - Frishman WH -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Piperazines) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Thiophenes) -RN - A74586SNO7 (Clopidogrel) -RN - G89JQ59I13 (Prasugrel Hydrochloride) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Cardiovascular Diseases/*drug therapy/*prevention & control -MH - Clopidogrel -MH - Dose-Response Relationship, Drug -MH - Hemorrhage/epidemiology -MH - Humans -MH - Piperazines/adverse effects/pharmacokinetics/*therapeutic use -MH - Platelet Aggregation Inhibitors/adverse effects/pharmacokinetics/*therapeutic use -MH - Prasugrel Hydrochloride -MH - Risk Factors -MH - Thiophenes/adverse effects/pharmacokinetics/*therapeutic use -MH - Ticlopidine/analogs & derivatives/pharmacokinetics/therapeutic use -RF - 52 -EDAT- 2008/10/17 09:00 -MHDA- 2008/12/31 09:00 -CRDT- 2008/10/17 09:00 -PHST- 2008/10/17 09:00 [pubmed] -PHST- 2008/12/31 09:00 [medline] -PHST- 2008/10/17 09:00 [entrez] -AID - 00045415-200811000-00006 [pii] -AID - 10.1097/CRD.0b013e318189a701 [doi] -PST - ppublish -SO - Cardiol Rev. 2008 Nov-Dec;16(6):314-8. doi: 10.1097/CRD.0b013e318189a701. - -PMID- 16910266 -OWN - NLM -STAT- MEDLINE -DCOM- 20061030 -LR - 20150826 -IS - 0370-629X (Print) -IS - 0370-629X (Linking) -VI - 61 -IP - 5-6 -DP - 2006 May-Jun -TI - [Do statins have a place for cardiovascular prevention in elderly people?]. -PG - 386-93 -AB - Cardiovascular prevention should only be considered if the treatment reduces the - incidence of coronary and cerebrovascular events and death. In elderly people, - such treatment should also, and most importantly, help maintain a good quality of - life, without increasing the risk of iatrogenic side-effects. These key-elements - should be kept in mind when prescription of a statin is envisaged in the old (> - 70 years) and especially the very old (> 80 years) individual. Randomised - controlled trials in people above 70 years are rather rare. In the field of - cardiovascular prevention, two studies provide information, on post-hoc analysis - of the Heart Protection Study (HPS) with simvastatin and the PROSPER trial with - pravastatin. The protection observed in the general population of HPS was also - present in the subgroup of subjects aged above 70, both for coronary and - cardiovascular events. The difference was less impressive in PROSPER, without any - significant difference as far as the incidence of stroke was concerned. None of - these two prospective trials provide specific data on individuals above 80. - Interestingly, some experimental and epidemiological observations suggested that - statins may prevent Alzheimer disease. However, the data from HPS and PROSPER are - not convincing in this respect. Thus, results from new ongoing trials should be - awaited, especially in patients with mild to moderate Alzheimer disease. Finally, - it is noteworthy that low serum cholesterol level can be used as a marker of poor - nutrition in very old people. Such condition is rather common, especially among - institutionalised subjects, and is usually associated with a higher risk of - morbidity and mortality. -FAU - Petermans, J -AU - Petermans J -AD - Service de Gériatrie, CHU Liège, Belgique. jean.petermans@chu.ulg.ac.be -FAU - Laperche, J -AU - Laperche J -FAU - Scheen, A J -AU - Scheen AJ -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Quelle place pour la prévention cardio-vasculaire par statine chez les personnes - agées? -PL - Belgium -TA - Rev Med Liege -JT - Revue medicale de Liege -JID - 0404317 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Cardiovascular Diseases/*prevention & control -MH - Controlled Clinical Trials as Topic -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Stroke/prevention & control -RF - 40 -EDAT- 2006/08/17 09:00 -MHDA- 2006/10/31 09:00 -CRDT- 2006/08/17 09:00 -PHST- 2006/08/17 09:00 [pubmed] -PHST- 2006/10/31 09:00 [medline] -PHST- 2006/08/17 09:00 [entrez] -PST - ppublish -SO - Rev Med Liege. 2006 May-Jun;61(5-6):386-93. - -PMID- 21241757 -OWN - NLM -STAT- MEDLINE -DCOM- 20111027 -LR - 20161125 -IS - 1872-8294 (Electronic) -IS - 0169-409X (Linking) -VI - 63 -IP - 8 -DP - 2011 Jul 18 -TI - Regulatory systems for hypoxia-inducible gene expression in ischemic heart - disease gene therapy. -PG - 678-87 -LID - 10.1016/j.addr.2011.01.003 [doi] -AB - Ischemic heart diseases are caused by narrowed coronary arteries that decrease - the blood supply to the myocardium. In the ischemic myocardium, - hypoxia-responsive genes are up-regulated by hypoxia-inducible factor-1 (HIF-1). - Gene therapy for ischemic heart diseases uses genes encoding angiogenic growth - factors and anti-apoptotic proteins as therapeutic genes. These genes increase - blood supply into the myocardium by angiogenesis and protect cardiomyocytes from - cell death. However, non-specific expression of these genes in normal tissues may - be harmful, since growth factors and anti-apoptotic proteins may induce tumor - growth. Therefore, tight gene regulation is required to limit gene expression to - ischemic tissues, to avoid unwanted side effects. For this purpose, various gene - expression strategies have been developed for ischemic-specific gene expression. - Transcriptional, post-transcriptional, and post-translational regulatory - strategies have been developed and evaluated in ischemic heart disease animal - models. The regulatory systems can limit therapeutic gene expression to ischemic - tissues and increase the efficiency of gene therapy. In this review, recent - progresses in ischemic-specific gene expression systems are presented, and their - applications to ischemic heart diseases are discussed. -CI - Copyright © 2011 Elsevier B.V. All rights reserved. -FAU - Kim, Hyun Ah -AU - Kim HA -AD - Department of Bioengineering, College of Engineering, Hanyang University, Seoul - 133-791, Republic of Korea. -FAU - Rhim, Taiyoun -AU - Rhim T -FAU - Lee, Minhyung -AU - Lee M -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110115 -PL - Netherlands -TA - Adv Drug Deliv Rev -JT - Advanced drug delivery reviews -JID - 8710523 -RN - 0 (Hypoxia-Inducible Factor 1) -SB - IM -MH - Animals -MH - Disease Models, Animal -MH - *Gene Expression Regulation -MH - Genetic Therapy/*methods -MH - Humans -MH - Hypoxia/genetics -MH - Hypoxia-Inducible Factor 1/genetics/metabolism -MH - Myocardial Ischemia/physiopathology/*therapy -EDAT- 2011/01/19 06:00 -MHDA- 2011/10/28 06:00 -CRDT- 2011/01/19 06:00 -PHST- 2010/11/15 00:00 [received] -PHST- 2010/12/29 00:00 [revised] -PHST- 2011/01/05 00:00 [accepted] -PHST- 2011/01/19 06:00 [entrez] -PHST- 2011/01/19 06:00 [pubmed] -PHST- 2011/10/28 06:00 [medline] -AID - S0169-409X(11)00007-X [pii] -AID - 10.1016/j.addr.2011.01.003 [doi] -PST - ppublish -SO - Adv Drug Deliv Rev. 2011 Jul 18;63(8):678-87. doi: 10.1016/j.addr.2011.01.003. - Epub 2011 Jan 15. - -PMID- 22179340 -OWN - NLM -STAT- MEDLINE -DCOM- 20120215 -LR - 20131121 -IS - 1530-0293 (Electronic) -IS - 0090-3493 (Linking) -VI - 40 -IP - 1 -DP - 2012 Jan -TI - The ups and downs of heart rate. -PG - 239-45 -LID - 10.1097/CCM.0b013e318232e50c [doi] -AB - OBJECTIVE: To review the physiology of the regulation and determinants of heart - rate and the significance in the management of critically ill patients. DATA - SOURCES: The MEDLINE database, references from selected articles, and the - author's personal database. DATA SYNTHESIS: This review begins with the - regulation of cardiac output and heart rate during exercise because this - demonstrates the range of physiological responses in the normal human. This - analysis shows that change in heart rate is a major component of the - cardiovascular system's ability to adjust cardiac output and a number of - regulatory systems control heart rate. When heart rate responses are limited - because of disease or pharmacologic reasons, changes in stroke volume must - compensate, but the capacity to do so is limited by the passive filling - characteristics of the ventricles. On the other side, high heart rates increase - myocardial oxygen demand, which can be a problem in patients with fixed coronary - artery disease. CONCLUSION: Heart rate must be interpreted in the context of the - patient's overall hemodynamic condition. The prudent physician must ask why is - the heart rate high, what will be achieved by lowering the heart rate, and, - finally, what are the consequences of lowering the heart rate? -FAU - Magder, Sheldon A -AU - Magder SA -AD - McGill University Health Centre, Montreal, Quebec, Canada. - sheldon.magder@muhc.mcgill.ca -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Med -JT - Critical care medicine -JID - 0355501 -RN - 0 (Adrenergic beta-1 Receptor Antagonists) -RN - GEB06NHM23 (Metoprolol) -SB - IM -MH - Adrenergic beta-1 Receptor Antagonists/pharmacology -MH - Atrial Fibrillation/physiopathology -MH - Blood Pressure/physiology -MH - Cardiac Output/physiology -MH - *Critical Illness -MH - Heart/physiology/physiopathology -MH - Heart Rate/drug effects/*physiology -MH - Humans -MH - Metoprolol/pharmacology -EDAT- 2011/12/20 06:00 -MHDA- 2012/02/16 06:00 -CRDT- 2011/12/20 06:00 -PHST- 2011/12/20 06:00 [entrez] -PHST- 2011/12/20 06:00 [pubmed] -PHST- 2012/02/16 06:00 [medline] -AID - 00003246-201201000-00035 [pii] -AID - 10.1097/CCM.0b013e318232e50c [doi] -PST - ppublish -SO - Crit Care Med. 2012 Jan;40(1):239-45. doi: 10.1097/CCM.0b013e318232e50c. - -PMID- 23265597 -OWN - NLM -STAT- MEDLINE -DCOM- 20130528 -LR - 20220410 -IS - 1548-5609 (Electronic) -IS - 1548-5595 (Linking) -VI - 20 -IP - 1 -DP - 2013 Jan -TI - Cardiorenal syndrome in critical care: the acute cardiorenal and renocardiac - syndromes. -PG - 56-66 -LID - S1548-5595(12)00200-5 [pii] -LID - 10.1053/j.ackd.2012.10.005 [doi] -AB - Heart and kidney disease often coexist in the same patient, and observational - studies have shown that cardiac disease can directly contribute to worsening - kidney function and vice versa. Cardiorenal syndrome (CRS) is defined as a - complex pathophysiological disorder of the heart and the kidneys in which acute - or chronic dysfunction in one organ may induce acute or chronic dysfunction in - the other organ. This has been recently classified into five subtypes on the - basis of the primary organ dysfunction (heart or kidney) and on whether the organ - dysfunction is acute or chronic. Of particular interest to the critical care - specialist are CRS type 1 (acute cardiorenal syndrome) and type 3 (acute - renocardiac syndrome). CRS type 1 is characterized by an acute deterioration in - cardiac function that leads to acute kidney injury (AKI); in CRS type 3, AKI - leads to acute cardiac injury and/or dysfunction, such as cardiac ischemic - syndromes, congestive heart failure, or arrhythmia. Both subtypes are encountered - in high-acuity medical units; in particular, CRS type 1 is commonly seen in the - coronary care unit and cardiothoracic intensive care unit. This paper will - provide a concise review of the epidemiology, pathophysiology, prevention - strategies, and selected kidney management aspects for these two acute CRS - subtypes. -CI - Copyright © 2013 National Kidney Foundation, Inc. Published by Elsevier Inc. All - rights reserved. -FAU - Cruz, Dinna N -AU - Cruz DN -AD - Department of Nephrology Dialysis & Transplantation, San Bortolo Hospital; and - International Renal Research Institute, 36100 Vicenza, Italy. - dinnacruzmd@yahoo.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Adv Chronic Kidney Dis -JT - Advances in chronic kidney disease -JID - 101209214 -SB - IM -MH - Acute Disease -MH - *Cardio-Renal Syndrome/classification/epidemiology/physiopathology/therapy -MH - Combined Modality Therapy -MH - Critical Care/*methods -MH - Humans -EDAT- 2012/12/26 06:00 -MHDA- 2013/05/29 06:00 -CRDT- 2012/12/26 06:00 -PHST- 2012/08/02 00:00 [received] -PHST- 2012/10/19 00:00 [revised] -PHST- 2012/10/19 00:00 [accepted] -PHST- 2012/12/26 06:00 [entrez] -PHST- 2012/12/26 06:00 [pubmed] -PHST- 2013/05/29 06:00 [medline] -AID - S1548-5595(12)00200-5 [pii] -AID - 10.1053/j.ackd.2012.10.005 [doi] -PST - ppublish -SO - Adv Chronic Kidney Dis. 2013 Jan;20(1):56-66. doi: 10.1053/j.ackd.2012.10.005. - -PMID- 22593934 -STAT- Publisher -ISBN- 978-1-4398-0713-2 -PB - CRC Press/Taylor & Francis -EN - 2nd -DP - 2011 -TI - Cardiovascular Disease. -BTI - Herbal Medicine: Biomolecular and Clinical Aspects -CP - Chapter 16 -AB - The cardiovascular diseases (CVDs) considered in this chapter have been the major - cause of morbidity and mortality in developed countries over the last several - decades, and developing countries are rapidly catching up with this epidemic. The - underlying pathology is atheromatous vascular disease, resulting in coronary - artery disease (CAD), cerebrovascular disease, and peripheral vascular disease, - and the subsequent development of heart failure and cardiac arrhythmias. The - major risk factors for these disorders were recognized over many years, and they - include high levels of low-density lipoprotein (LDL) cholesterol, smoking, - hypertension, diabetes, abdominal obesity, psychosocial factors, insufficient - consumption of fruits and vegetables, excess consumption of alcohol, and lack of - regular physical activity. There has been continued research to help define more - precisely the cardiovascular risk of an individual with respect to genetic - factors, more complex lipid traits, and inflammatory markers, but it was - reconfirmed in the INTERHEART study that the conventional risk factors accounted - for over 90% of the population attributable risk for myocardial infarction (MI; - Yusuf et al. 2004). There is extensive evidence to show that drug treatment of - conventional risk factors is effective in reducing cardiovascular events. Many - large clinical trials with the HMG CoA reductase inhibitors (statins) have showed - that lowering of LDL cholesterol with these agents decreases coronary and - cerebrovascular events (Baigent et al. 2005), and that the target for LDL - cholesterol becomes lower with each new set of guidelines and the availability of - more potent drugs (Anderson et al. 2007). Likewise, more effective treatment of - hypertension with various classes of antihypertensive drugs has been associated - with greater benefits (Turnbull et al. 2008), but some recent studies suggest we - may be reaching the optimal level of treated blood pressure in some patient - groups (ACCORD Study Group 2010). Apart from the treatment of cardiovascular risk - factors with pharmacological agents and the use of antithrombotic drugs, there is - growing awareness of the role of dietary factors and herbal medicines in the - prevention of CVD and the possibility of their use in treatment. Much of this - interest centers on the use of antioxidant vitamins and the antioxidant - properties of herbal materials, although some herbal materials may also improve - conventional cardiovascular risk factors or have antithrombotic effects. In this - chapter, we focus mainly on the results from large clinical trials and - meta-analyses rather than from mechanistic studies, and we start by considering - the use of antioxidant vitamins and other essential micronutrients in Section - 16.2 before moving to a discussion of individual herbs in Section 16.3. -CI - Copyright © 2011 by Taylor and Francis Group, LLC. -FED - Benzie, Iris F F -ED - Benzie IFF -FED - Wachtel-Galor, Sissi -ED - Wachtel-Galor S -FAU - Walden, Richard -AU - Walden R -FAU - Tomlinson, Brian -AU - Tomlinson B -LA - eng -PT - Review -PT - Book Chapter -PL - Boca Raton (FL) -EDAT- 2011/01/01 00:00 -CRDT- 2011/01/01 00:00 -AID - NBK92767 [bookaccession] - -PMID- 24158692 -OWN - NLM -STAT- MEDLINE -DCOM- 20140409 -LR - 20220331 -IS - 1435-1803 (Electronic) -IS - 0300-8428 (Linking) -VI - 108 -IP - 6 -DP - 2013 Nov -TI - Redox balance and cardioprotection. -PG - 392 -LID - 10.1007/s00395-013-0392-7 [doi] -AB - Coronary artery disease is a major cause of morbidity and mortality in the - Western countries. Acute myocardial infarction is a serious and often lethal - consequence of coronary artery disease, resulting in contractile dysfunction and - cell death. It is well known that unbalanced and high steady state levels of - reactive oxygen and nitrogen species (ROS/RNS) are responsible for cytotoxicity, - which in heart leads to contractile dysfunction and cell death. Pre- and - post-conditioning of the myocardium are two treatment strategies that reduce - contractile dysfunction and the amount of cell death considerably. Paradoxically, - ROS and RNS have been identified as a part of cardioprotective signaling - molecules, which are essential in pre- and post-conditioning processes. - S-nitrosylation of proteins is a specific posttranslational modification that - plays an important role in cardioprotection, especially within mitochondria. In - fact, mitochondria are of paramount importance in either promoting or limiting - ROS/RNS generation and reperfusion injury, and in triggering kinase activation by - ROS/RNS signaling in cardioprotection. These organelles are also the targets of - acidosis, which prevents mitochondrial transition pore opening, thus avoiding - ROS-induced ROS release. Therefore, we will consider mitochondria as either - targets of damage or protection from it. The origin of ROS/RNS and the - cardioprotective signaling pathways involved in ROS/RNS-based pre- and - post-conditioning will be explored in this article. A particular emphasis will be - given to new aspects concerning the processes of S-nitrosylation in the - cardioprotective scenario. -FAU - Tullio, Francesca -AU - Tullio F -AD - Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Ospedale S. - Luigi, Regione Gonzole,10, 10043, Orbassano (TO), Italy. -FAU - Angotti, Carmelina -AU - Angotti C -FAU - Perrelli, Maria-Giulia -AU - Perrelli MG -FAU - Penna, Claudia -AU - Penna C -FAU - Pagliaro, Pasquale -AU - Pagliaro P -LA - eng -PT - Journal Article -PT - Review -DEP - 20131025 -PL - Germany -TA - Basic Res Cardiol -JT - Basic research in cardiology -JID - 0360342 -RN - 0 (Reactive Nitrogen Species) -RN - 0 (Reactive Oxygen Species) -SB - IM -MH - Animals -MH - Humans -MH - Ischemic Preconditioning, Myocardial/methods -MH - Mitochondria/metabolism -MH - Myocardial Infarction/*physiopathology -MH - Myocardial Reperfusion Injury/*physiopathology -MH - Myocardium/metabolism -MH - Oxidation-Reduction -MH - Oxidative Stress/physiology -MH - Reactive Nitrogen Species/metabolism -MH - Reactive Oxygen Species/metabolism -MH - Reperfusion Injury/*physiopathology -EDAT- 2013/10/26 06:00 -MHDA- 2014/04/10 06:00 -CRDT- 2013/10/26 06:00 -PHST- 2013/07/23 00:00 [received] -PHST- 2013/10/14 00:00 [accepted] -PHST- 2013/09/24 00:00 [revised] -PHST- 2013/10/26 06:00 [entrez] -PHST- 2013/10/26 06:00 [pubmed] -PHST- 2014/04/10 06:00 [medline] -AID - 10.1007/s00395-013-0392-7 [doi] -PST - ppublish -SO - Basic Res Cardiol. 2013 Nov;108(6):392. doi: 10.1007/s00395-013-0392-7. Epub 2013 - Oct 25. - -PMID- 19520307 -OWN - NLM -STAT- MEDLINE -DCOM- 20090827 -LR - 20121107 -IS - 1878-1594 (Electronic) -IS - 1521-690X (Linking) -VI - 23 -IP - 3 -DP - 2009 Jun -TI - Peripheral and cerebrovascular atherosclerotic disease in diabetes mellitus. -PG - 335-45 -LID - 10.1016/j.beem.2008.10.015 [doi] -AB - Diabetes mellitus is frequently associated with atherosclerotic vascular disease - involving the coronary, peripheral and cerebrovascular circulation. Compared with - non-diabetic counterparts, peripheral arterial disease (PAD) in diabetic - individuals is more diffuse and often involves the popliteal and below-knee - arteries. The goal of treatment in diabetic patients with PAD, as in other - patients with this condition, is to aggressively treat atherosclerotic risk - factors to reduce future cardiovascular events as well as to improve symptoms of - claudication and prevent limb amputation. Diabetes is also associated with a - heightened risk of stroke which is a common cause of morbidity and mortality in - diabetic individuals. Optimal blood pressure control is paramount in reducing the - future risk of stroke in these patients. Clinicians need to be aware of the - strong association between diabetes and non-coronary atherosclerosis and use - appropriate medical and interventional treatments to reduce the associated - disability and mortality in these patients. -FAU - Mukherjee, Debabrata -AU - Mukherjee D -AD - Gill Heart Institute, Division of Cardiovascular Medicine, University of - Kentucky, Lexington, KY 40536-0200, USA. mukherjee@uky.edu -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Best Pract Res Clin Endocrinol Metab -JT - Best practice & research. Clinical endocrinology & metabolism -JID - 101120682 -SB - IM -MH - Aged -MH - Atherosclerosis/*etiology -MH - Cerebrovascular Disorders/*etiology -MH - Diabetes Complications/*therapy -MH - Diabetes Mellitus, Type 2/complications -MH - Humans -MH - Middle Aged -MH - Peripheral Vascular Diseases/diagnosis/*etiology/therapy -MH - Risk Factors -MH - Stroke/prevention & control/therapy -RF - 61 -EDAT- 2009/06/13 09:00 -MHDA- 2009/08/28 09:00 -CRDT- 2009/06/13 09:00 -PHST- 2009/06/13 09:00 [entrez] -PHST- 2009/06/13 09:00 [pubmed] -PHST- 2009/08/28 09:00 [medline] -AID - S1521-690X(08)00145-0 [pii] -AID - 10.1016/j.beem.2008.10.015 [doi] -PST - ppublish -SO - Best Pract Res Clin Endocrinol Metab. 2009 Jun;23(3):335-45. doi: - 10.1016/j.beem.2008.10.015. - -PMID- 22331054 -OWN - NLM -STAT- MEDLINE -DCOM- 20120626 -LR - 20211021 -IS - 1432-1971 (Electronic) -IS - 0172-0643 (Linking) -VI - 33 -IP - 3 -DP - 2012 Mar -TI - Noninvasive imaging modalities and sudden cardiac arrest in the young: can they - help distinguish subjects with a potentially life-threatening abnormality from - normals? -PG - 439-51 -LID - 10.1007/s00246-012-0169-z [doi] -AB - Sudden cardiac arrest (SCA) in the young is always tragic, but fortunately it is - an unusual event. When it does occur, it usually happens in active individuals, - often while they are participating in physical activity. Depending on the - population's characteristics, the most common causes of sudden cardiac arrest in - these subjects are hypertrophic cardiomyopathy, congenital coronary - abnormalities, arrhythmia in the presence of a structurally normal heart (ion - channelopathies or abnormal conduction pathways), aortic rupture, and - arrhythmogenic right-ventricular cardiomyopathy. Two-dimensional echocardiography - (2-DE) has been proposed as a screening tool that can potentially detect four of - these five causes of SCA, and many groups now sponsor community-based 2-DE - SCA-screening programs. "Basic" 2-DE screening may include assessment of - ventricular volumes, mass, and function; left atrial size; and cardiac and - thoracic vascular (including coronary) anatomy. "Advanced" echocardiographic - techniques, such as tissue Doppler and strain imaging, can help in diagnosis when - the history, electrocardiogram (ECG), and/or standard 2-DE screening suggest - there may be an abnormality, e.g., to help differentiate those with "athlete's - heart" from hypertrophic or dilated cardiomyopathy. Cardiac magnetic resonance - imaging or cardiac computed tomography can be added to increase diagnostic - sensitivity and specificity in select cases when an abnormality is suggested - during SCA screening. Test availability, cost, and ethical issues related to who - to screen, as well as the detection of those with potential disease but low risk, - must be balanced when deciding what tests to perform to assess for increased SCA - risk. -FAU - Printz, Beth Feller -AU - Printz BF -AD - Division of Cardiology, Department of Pediatrics, Rady Children's Hospital, San - Diego and University of California, San Diego, 3030 Children's Way, San Diego, CA - 92123, USA. bprintz@rchsd.org -LA - eng -PT - Journal Article -PT - Review -DEP - 20120214 -PL - United States -TA - Pediatr Cardiol -JT - Pediatric cardiology -JID - 8003849 -SB - IM -MH - Adolescent -MH - Age Factors -MH - American Heart Association -MH - Cardiomyopathy, Dilated/diagnosis/epidemiology/pathology -MH - Cardiomyopathy, Hypertrophic/diagnosis/pathology/prevention & control -MH - Death, Sudden, Cardiac/epidemiology/pathology/*prevention & control -MH - Echocardiography -MH - Health Status -MH - Humans -MH - Myocarditis/diagnosis/epidemiology/pathology -MH - Risk Assessment/methods -MH - *Sports -MH - *Sports Medicine -MH - United States -EDAT- 2012/02/15 06:00 -MHDA- 2012/06/27 06:00 -CRDT- 2012/02/15 06:00 -PHST- 2011/09/23 00:00 [received] -PHST- 2011/10/04 00:00 [accepted] -PHST- 2012/02/15 06:00 [entrez] -PHST- 2012/02/15 06:00 [pubmed] -PHST- 2012/06/27 06:00 [medline] -AID - 10.1007/s00246-012-0169-z [doi] -PST - ppublish -SO - Pediatr Cardiol. 2012 Mar;33(3):439-51. doi: 10.1007/s00246-012-0169-z. Epub 2012 - Feb 14. - -PMID- 20425492 -OWN - NLM -STAT- MEDLINE -DCOM- 20100914 -LR - 20211020 -IS - 1546-9549 (Electronic) -IS - 1546-9530 (Linking) -VI - 7 -IP - 1 -DP - 2010 Mar -TI - An update on cardiac troponins as circulating biomarkers in heart failure. -PG - 15-21 -LID - 10.1007/s11897-010-0001-0 [doi] -AB - Circulating troponins and natriuretic peptides are the only biomarkers - specifically released from cardiac myocytes that can be determined with robust - and sensitive analytical methods, even in healthy subjects. These intracellular - proteins are released from reversibly or irreversibly damaged cardiac myocytes - into the bloodstream by mechanisms that are not entirely clear. The recent - introduction of a new generation of highly sensitive assays of cardiac troponin I - or T has not only improved the early diagnosis of acute myocardial infarction but - also suggested that there are several causes for troponin release other than - acute coronary syndromes. Circulating troponins are elevated in patients with - acute or chronic heart failure and are strongly associated with outcome, - independently of natriuretic peptides, the benchmark biomarkers in heart failure. - In the absence of further experimental evidences, the pathophysiologic basis for - the elevation of circulating cardiac troponins in patients with stable chronic - heart failure remains speculative. -FAU - Masson, Serge -AU - Masson S -AD - Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario - Negri, via Giuseppe La Masa 19, 20156, Milan, Italy. serge.masson@marionegri.it -FAU - Latini, Roberto -AU - Latini R -FAU - Anand, Inder S -AU - Anand IS -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Heart Fail Rep -JT - Current heart failure reports -JID - 101196487 -RN - 0 (Troponin I) -RN - 0 (Troponin T) -SB - IM -MH - Chronic Disease -MH - Heart Failure/*blood/*physiopathology -MH - Humans -MH - Sensitivity and Specificity -MH - Troponin I/*blood -MH - Troponin T/*blood -RF - 46 -EDAT- 2010/04/29 06:00 -MHDA- 2010/09/15 06:00 -CRDT- 2010/04/29 06:00 -PHST- 2010/04/29 06:00 [entrez] -PHST- 2010/04/29 06:00 [pubmed] -PHST- 2010/09/15 06:00 [medline] -AID - 10.1007/s11897-010-0001-0 [doi] -PST - ppublish -SO - Curr Heart Fail Rep. 2010 Mar;7(1):15-21. doi: 10.1007/s11897-010-0001-0. - -PMID- 23217461 -OWN - NLM -STAT- MEDLINE -DCOM- 20130606 -LR - 20161125 -IS - 1876-861X (Electronic) -IS - 1876-861X (Linking) -VI - 6 -IP - 6 -DP - 2012 Nov-Dec -TI - Evaluation of valvular disease by cardiac computed tomography assessment. -PG - 381-92 -LID - S1934-5925(12)00363-2 [pii] -LID - 10.1016/j.jcct.2012.10.007 [doi] -AB - Cardiac multidetector computed tomography (MDCT) angiography is emerging as a - technique to evaluate cardiac valve structure and function. MDCT can provide - insights into cardiac valve anatomy and pathologic states, including comparable - efficacy in valve area and regurgitant orifice area assessment compared with - echocardiography and magnetic resonance imaging. MDCT can also be useful when - initial evaluation of valvular disease with echocardiography yields suboptimal - images. MDCT provides concurrent visualization of coronary anatomy which may - avoid the need for further invasive preoperative testing. Overall, more studies - have shown the utility of MDCT in imaging of left-sided valves (aortic and - mitral), whereas its ability in assessing right-sided valves (tricuspid and - pulmonary) is somewhat limited. MDCT has shown promise as a valuable adjunctive - imaging tool to conventional imaging modalities in providing essential anatomic - and physiologic data on the sequelae of valvular dysfunction, with the potential - of guiding both surgical and percutaneous management. MDCT technology continues - to evolve, and more studies are indicated to further refine its precise role in - the evaluation of patients with valvular pathology. -CI - Copyright © 2012 Society of Cardiovascular Computed Tomography. Published by - Elsevier Inc. All rights reserved. -FAU - Buttan, Anshu K -AU - Buttan AK -AD - School of Medicine, University of California at Irvine, Irvine, CA, USA. -FAU - Yang, Eric H -AU - Yang EH -FAU - Budoff, Matthew J -AU - Budoff MJ -FAU - Vorobiof, Gabriel -AU - Vorobiof G -LA - eng -PT - Journal Article -PT - Review -DEP - 20121103 -PL - United States -TA - J Cardiovasc Comput Tomogr -JT - Journal of cardiovascular computed tomography -JID - 101308347 -SB - IM -MH - Heart Valve Diseases/*diagnostic imaging -MH - Heart Valves/*diagnostic imaging -MH - Humans -MH - Myocardial Perfusion Imaging/*methods -MH - Tomography, X-Ray Computed/*methods -EDAT- 2012/12/12 06:00 -MHDA- 2013/06/07 06:00 -CRDT- 2012/12/11 06:00 -PHST- 2012/08/16 00:00 [received] -PHST- 2012/10/30 00:00 [revised] -PHST- 2012/10/31 00:00 [accepted] -PHST- 2012/12/11 06:00 [entrez] -PHST- 2012/12/12 06:00 [pubmed] -PHST- 2013/06/07 06:00 [medline] -AID - S1934-5925(12)00363-2 [pii] -AID - 10.1016/j.jcct.2012.10.007 [doi] -PST - ppublish -SO - J Cardiovasc Comput Tomogr. 2012 Nov-Dec;6(6):381-92. doi: - 10.1016/j.jcct.2012.10.007. Epub 2012 Nov 3. - -PMID- 23990345 -OWN - NLM -STAT- MEDLINE -DCOM- 20140919 -LR - 20240130 -IS - 1532-6551 (Electronic) -IS - 1071-3581 (Linking) -VI - 20 -IP - 6 -DP - 2013 Dec -TI - The role of radionuclide imaging in heart failure. -PG - 1173-83 -LID - 10.1007/s12350-013-9776-1 [doi] -AB - The incidence of heart failure (HF) is increasing and it remains the only area in - cardiovascular disease wherein hospitalization rates and mortalities have - worsened in the past 25 years. This review is provided to assess the role of - radionuclide imaging in HF. The focus is on three aspects: the value of nuclear - imaging to distinguish ischemic from non-ischemic etiologies; risk stratification - of patients with HF with evaluation of candidates for specific treatment - strategies; and the role of cardiac neuronal imaging in patients with HF. - Distinguishing ischemic from non-ischemic cardiomyopathy is important because - patients with ischemic cardiomyopathy can potentially have dramatic improvement - with revascularization. Single photon emission computed tomography (SPECT) has - excellent reported sensitivity and negative predictive value in the detection of - coronary artery disease in HF patients. SPECT imaging is also useful in - establishing treatment strategies in patients with HF, including those with new - onset CHF. Cardiac neuronal imaging of mIBG is particularly helpful in risk - stratification of patients with HF. The modality can be used to monitor the - response to therapy as dysfunctional mIBG uptake may show improvement with - pharmacological treatment. -FAU - Gulati, Vinay -AU - Gulati V -AD - University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT, - 06030, USA, drvinaygulati@gmail.com. -FAU - Ching, Gilbert -AU - Ching G -FAU - Heller, Gary V -AU - Heller GV -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Nucl Cardiol -JT - Journal of nuclear cardiology : official publication of the American Society of - Nuclear Cardiology -JID - 9423534 -SB - IM -MH - Heart Failure/*diagnostic imaging -MH - Humans -MH - Myocardial Ischemia/diagnostic imaging -MH - Myocardial Perfusion Imaging -MH - Positron-Emission Tomography -MH - Tomography, Emission-Computed, Single-Photon -MH - Ventricular Function, Left -EDAT- 2013/08/31 06:00 -MHDA- 2014/09/23 06:00 -CRDT- 2013/08/31 06:00 -PHST- 2013/08/31 06:00 [entrez] -PHST- 2013/08/31 06:00 [pubmed] -PHST- 2014/09/23 06:00 [medline] -AID - S1071-3581(23)03369-X [pii] -AID - 10.1007/s12350-013-9776-1 [doi] -PST - ppublish -SO - J Nucl Cardiol. 2013 Dec;20(6):1173-83. doi: 10.1007/s12350-013-9776-1. - -PMID- 23422241 -OWN - NLM -STAT- MEDLINE -DCOM- 20130926 -LR - 20151119 -IS - 1752-2978 (Electronic) -IS - 1752-296X (Linking) -VI - 20 -IP - 2 -DP - 2013 Apr -TI - Update on the detection and treatment of atherogenic low-density lipoproteins. -PG - 140-7 -LID - 10.1097/MED.0b013e32835ed9cb [doi] -AB - PURPOSE OF REVIEW: To explain why epidemiological studies have reached such - diverse views as to whether apolipoprotein B (apoB) and/or low-density - lipoprotein particle number (LDL-P) are more accurate markers of the risk of - cardiovascular disease than LDL-C or non-high-density lipoprotein cholesterol - (HDL-C) and to review the treatment options to lower LDL. RECENT FINDINGS: The - Emerging Risk Factor Collaboration, a large prospective participant level - analysis, a meta-analysis of statin clinical trials, and the Heart Protection - Study have each reported that apoB does not add significantly to the cholesterol - markers as indices of cardiovascular risk. By contrast, a meta-analysis of - published prospective studies demonstrated that non-HDL-C was superior to LDL-C, - and apoB was superior to non-HDL-C. As well, three studies using discordance - analysis each demonstrated that apoB and LDL-P were superior to the cholesterol - markers. Two approaches to resolve these differences are brought to bear in this - article: first, which results are credible and second, how does taking the known - differences in LDL composition into account, help resolve them. The best - identification of individuals at risk of coronary artery disease or with coronary - artery disease allows the most efficacious treatment of elevated LDL-P and will - permit a more extensive use of some of the more novel LDL-lowering agents. - SUMMARY: Much of the controversy vanishes once the physiologically driven - differences in the composition of the apoB lipoprotein particles are taken into - account, illustrating that epidemiology, not directed by physiology, is like - shooting without aiming. -FAU - Sniderman, Allan -AU - Sniderman A -AD - Division of Cardiology, McGill University Health Centre, Montreal, Quebec, - Canada. -FAU - Kwiterovich, Peter O -AU - Kwiterovich PO -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Curr Opin Endocrinol Diabetes Obes -JT - Current opinion in endocrinology, diabetes, and obesity -JID - 101308636 -RN - 0 (Apolipoproteins B) -RN - 0 (Biomarkers) -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Lipoproteins, LDL) -SB - IM -MH - Apolipoproteins B/*blood -MH - Atherosclerosis/*blood/drug therapy -MH - Biomarkers/blood -MH - Cholesterol, LDL/blood -MH - Diet, Fat-Restricted -MH - Female -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Lipoproteins, LDL/*blood -MH - Male -MH - Predictive Value of Tests -MH - Prospective Studies -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - Risk Factors -EDAT- 2013/02/21 06:00 -MHDA- 2013/09/27 06:00 -CRDT- 2013/02/21 06:00 -PHST- 2013/02/21 06:00 [entrez] -PHST- 2013/02/21 06:00 [pubmed] -PHST- 2013/09/27 06:00 [medline] -AID - 10.1097/MED.0b013e32835ed9cb [doi] -PST - ppublish -SO - Curr Opin Endocrinol Diabetes Obes. 2013 Apr;20(2):140-7. doi: - 10.1097/MED.0b013e32835ed9cb. - -PMID- 19591748 -OWN - NLM -STAT- MEDLINE -DCOM- 20090929 -LR - 20090713 -IS - 1535-6280 (Electronic) -IS - 0146-2806 (Linking) -VI - 34 -IP - 8 -DP - 2009 Aug -TI - Management of cardiogenic shock: focus on tissue perfusion. -PG - 330-49 -LID - 10.1016/j.cpcardiol.2009.04.002 [doi] -AB - Cardiogenic shock (CS) may result from ischemic heart disease, cardiomyopathy, - valvular heart disease, inflammation, myocardial contusion, and cardiac surgery. - CS is the leading cause of in-hospital death in patients with acute myocardial - infarction. Although early revascularization strategies have resulted in a better - prognosis, in-hospital mortality from CS remains exceptionally high. Notably, - long-term annual mortality is similar in survivors of CS relative to patients - with myocardial infarction without shock. This underlines the importance of - aggressive support of the failing heart in the acute phase of CS. Because CS - reflects a state of hypoperfusion induced by heart failure, management of CS - should aim at improving cardiac function as well as at optimization of tissue - perfusion. This review evaluates the current treatment of CS. In addition, novel - approaches to monitor and modulate peripheral circulation at the bedside are - highlighted. It is expected that these techniques will improve our understanding - of the pathogenesis of CS and will offer new opportunities to guide therapy in CS - patients to improve long-term prognosis. -FAU - den Uil, Corstiaan A -AU - den Uil CA -FAU - Lagrand, Wim K -AU - Lagrand WK -FAU - Valk, Suzanne D A -AU - Valk SD -FAU - Spronk, Peter E -AU - Spronk PE -FAU - Simoons, Maarten L -AU - Simoons ML -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Curr Probl Cardiol -JT - Current problems in cardiology -JID - 7701802 -RN - 0 (Cardiotonic Agents) -RN - 0 (Vasodilator Agents) -SB - IM -CIN - Curr Probl Cardiol. 2009 Aug;34(8):327. doi: 10.1016/j.cpcardiol.2009.04.001. - PMID: 19591747 -MH - Cardiotonic Agents/therapeutic use -MH - *Coronary Circulation -MH - Humans -MH - *Myocardial Reperfusion -MH - Perfusion -MH - Risk Factors -MH - Shock, Cardiogenic/drug therapy/etiology/*therapy -MH - Vasodilator Agents/therapeutic use -RF - 77 -EDAT- 2009/07/14 09:00 -MHDA- 2009/09/30 06:00 -CRDT- 2009/07/14 09:00 -PHST- 2009/07/14 09:00 [entrez] -PHST- 2009/07/14 09:00 [pubmed] -PHST- 2009/09/30 06:00 [medline] -AID - S0146-2806(09)00057-7 [pii] -AID - 10.1016/j.cpcardiol.2009.04.002 [doi] -PST - ppublish -SO - Curr Probl Cardiol. 2009 Aug;34(8):330-49. doi: 10.1016/j.cpcardiol.2009.04.002. - -PMID- 22467260 -OWN - NLM -STAT- MEDLINE -DCOM- 20120813 -LR - 20250529 -IS - 1534-3170 (Electronic) -IS - 1523-3782 (Linking) -VI - 14 -IP - 3 -DP - 2012 Jun -TI - Role of antithrombotic agents in heart failure. -PG - 314-25 -LID - 10.1007/s11886-012-0266-x [doi] -AB - Despite a vast body of research on antithrombotic therapy for patients with - cardiac disease, there are few clinical settings where robust evidence of their - benefit exists. Patients with heart failure often have vascular disease and - atrial fibrillation contributing to their poor prognosis. For patients with heart - failure and atrial fibrillation, anticoagulants are appropriate. For patients - with heart failure in sinus rhythm, the weight of evidence suggests that doctors - should generally avoid using any antithrombotic agent even if the patient has - coronary artery disease. If there is a compulsion to treat, then there is less - evidence of harm with clopidogrel or warfarin than with aspirin, although most - receive aspirin. More research is required for this "evidence-light" problem. For - those with the opportunity, engaging with a randomized trial is clinically and - scientifically appropriate. The dilemma for such studies is the comparator. - Should it be against or in addition to "standard of care" or both? -FAU - Cleland, John G F -AU - Cleland JG -AD - Department of Cardiology, Hull York Medical School (University of Hull), Castle - Hill Hospital, Kingston-upon-Hull, East Riding of Yorkshire, England, UK. - j.g.cleland@hull.ac.uk -FAU - Mumtaz, Saqib -AU - Mumtaz S -FAU - Cecchini, Luca -AU - Cecchini L -LA - eng -GR - 08/53/36/DH_/Department of Health/United Kingdom -GR - HTA/08/53/36/DH_/Department of Health/United Kingdom -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -RN - 0 (Fibrinolytic Agents) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Atrial Fibrillation/complications/drug therapy -MH - Contraindications -MH - Fibrinolytic Agents/*therapeutic use -MH - Heart Failure/complications/*drug therapy -MH - Humans -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Practice Guidelines as Topic -MH - Randomized Controlled Trials as Topic -MH - Thrombosis/etiology/*prevention & control -MH - Venous Thromboembolism/etiology/prevention & control -EDAT- 2012/04/03 06:00 -MHDA- 2012/08/14 06:00 -CRDT- 2012/04/03 06:00 -PHST- 2012/04/03 06:00 [entrez] -PHST- 2012/04/03 06:00 [pubmed] -PHST- 2012/08/14 06:00 [medline] -AID - 10.1007/s11886-012-0266-x [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2012 Jun;14(3):314-25. doi: 10.1007/s11886-012-0266-x. - -PMID- 22719141 -OWN - NLM -STAT- MEDLINE -DCOM- 20121029 -LR - 20211021 -IS - 1526-6702 (Electronic) -IS - 0730-2347 (Print) -IS - 0730-2347 (Linking) -VI - 39 -IP - 3 -DP - 2012 -TI - Implantable cardioverter-defibrillators: indications and unresolved issues. -PG - 335-41 -AB - Since the implantable cardioverter-defibrillator was first used clinically in - 1980, several large randomized controlled trials have shown that therapy with - this device can be beneficial in various patient populations. Evidence suggests - that this therapy is useful in the secondary prevention of sudden cardiac death - among patients who have survived arrhythmic events. Several trials have also - shown the usefulness of implantable cardioverter-defibrillator therapy in the - primary prevention of sudden cardiac death in patients with coronary artery - disease and nonischemic cardiomyopathy. Other data support the use of this device - for various infiltrative and inherited conditions. When used with cardiac - resynchronization therapy, implantable cardioverter-defibrillators have improved - survival rates and quality of life in patients with severe heart failure. Further - research is needed to examine the potential benefits of implantable - cardioverter-defibrillators in elderly, female, and hemodialysis-dependent - patients, and to determine the optimal waiting period for implantation after - myocardial infarction, coronary revascularization, and initial heart-failure - diagnosis. -FAU - Kedia, Rohit -AU - Kedia R -AD - Department of Cardiology, Texas Heart Institute at St. Luke's Episcopal Hospital, - Houston, Texas 77030, USA. -FAU - Saeed, Mohammad -AU - Saeed M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Tex Heart Inst J -JT - Texas Heart Institute journal -JID - 8214622 -SB - IM -MH - *Cardiac Resynchronization Therapy/adverse effects -MH - Death, Sudden, Cardiac/etiology/*prevention & control -MH - *Defibrillators, Implantable -MH - Electric Countershock/adverse effects/*instrumentation -MH - Equipment Design -MH - Heart Diseases/complications/mortality/*therapy -MH - Humans -MH - Patient Selection -MH - Primary Prevention/*instrumentation -MH - Risk Assessment -MH - Risk Factors -MH - Secondary Prevention/*instrumentation -MH - Treatment Outcome -PMC - PMC3368443 -OTO - NOTNLM -OT - Arrhythmias, cardiac/prevention & control/therapy -OT - cardiac pacing, artificial -OT - death, sudden, cardiac/prevention & control -OT - defibrillators, implantable/utilization -OT - outcome assessment (health care) -OT - randomized controlled trials as topic -OT - tachycardia, ventricular/therapy -OT - ventricular fibrillation/therapy -EDAT- 2012/06/22 06:00 -MHDA- 2012/10/30 06:00 -PMCR- 2012/01/01 -CRDT- 2012/06/22 06:00 -PHST- 2012/06/22 06:00 [entrez] -PHST- 2012/06/22 06:00 [pubmed] -PHST- 2012/10/30 06:00 [medline] -PHST- 2012/01/01 00:00 [pmc-release] -AID - 0010801-201206000-00007 [pii] -PST - ppublish -SO - Tex Heart Inst J. 2012;39(3):335-41. - -PMID- 18350717 -OWN - NLM -STAT- MEDLINE -DCOM- 20080422 -LR - 20080320 -IS - 0043-5147 (Print) -IS - 0043-5147 (Linking) -VI - 60 -IP - 9-10 -DP - 2007 -TI - [Proinflammatory cytokines in cardiovascular diseases as potential therapeutic - target]. -PG - 433-8 -AB - Several lines of evidence suggest that inflammation plays a pathogenic role in - the development and progression of congestive heart failure, influencing heart - contractility and hypertrophy, promoting apoptosis, and contributing to the - myocardial remodeling process. Proinflammatory cytokines are important mediators - of immune response, associated with endothelial dysfunction in patients with - coronary artery disease or heart failure. The presence, both at tissue level and - in the circulation, of increased levels of pro-inflammatory cytokines suggests - that immune activation might be a relevant mechanism contributing to cardiac as - well as peripheral manifestations of the disease. Traditional cardiovascular - drugs have little influence on the cytokine network. Results from randomized, - placebo controlled anti-TNF studies suggest lack of effect of such therapy, but - the concept of immune modulation is still intensively studied. In this review we - evaluate the diagnostic and prognostic value of the activation of proinflammatory - cytokines, theirs role in the pathogenesis of the cardiovascular diseases and the - new ways of treatment. -FAU - Bielecka-Dabrowa, Agata -AU - Bielecka-Dabrowa A -AD - Z Kliniki Kardiologii I Katedry Kardiologil i Kardiochirurgii Uniwersytctu - Medycznego w Łodzi. agatbiel7@poczta.onet.pl -FAU - Wierzbicka, Magdalena -AU - Wierzbicka M -FAU - Goch, Jan H -AU - Goch JH -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Cytokiny prozapalne w chorobach układu krazenia jako potencjalny cel - terapeutyczny. -PL - Poland -TA - Wiad Lek -JT - Wiadomosci lekarskie (Warsaw, Poland : 1960) -JID - 9705467 -RN - 0 (Cytokines) -RN - 0 (Inflammation Mediators) -SB - IM -MH - Cardiovascular Diseases/diagnosis/*immunology/*physiopathology/therapy -MH - Cytokines/*immunology -MH - Heart Failure/immunology/physiopathology -MH - Humans -MH - Inflammation Mediators/immunology -RF - 29 -EDAT- 2008/03/21 09:00 -MHDA- 2008/04/23 09:00 -CRDT- 2008/03/21 09:00 -PHST- 2008/03/21 09:00 [pubmed] -PHST- 2008/04/23 09:00 [medline] -PHST- 2008/03/21 09:00 [entrez] -PST - ppublish -SO - Wiad Lek. 2007;60(9-10):433-8. - -PMID- 22011751 -OWN - NLM -STAT- MEDLINE -DCOM- 20120123 -LR - 20220729 -IS - 1524-4636 (Electronic) -IS - 1079-5642 (Linking) -VI - 31 -IP - 11 -DP - 2011 Nov -TI - Circulating microRNAs: biomarkers or mediators of cardiovascular diseases? -PG - 2383-90 -LID - 10.1161/ATVBAHA.111.226696 [doi] -AB - MicroRNAs (miRs) are small, noncoding RNAs that posttranscriptionally control - gene expression by inhibiting protein translation or inducing target mRNA - destabilization. Besides their intracellular function, recent studies demonstrate - that miRs can be exported or released by cells and circulate with the blood in a - remarkably stable form. The discovery of circulating miRs opens up intriguing - possibilities to use the circulating miR patterns as biomarker for cardiovascular - diseases. Cardiac injury as it occurs after acute myocardial infarction increases - the circulating levels of several myocardial-derived miRs (eg, miR-1, miR-133, - miR-499, miR-208), whereas patients with coronary artery disease or diabetes - showed reduced levels of endothelial-enriched miRs, such as miR-126. This review - article summarizes the current clinical and experimental studies addressing the - role of circulating miRs as a diagnostic or prognostic biomarker in - cardiovascular disease. In addition, the mechanisms by which miRs are released - and their putative function as long-distance communicators are discussed. -FAU - Fichtlscherer, Stephan -AU - Fichtlscherer S -AD - Division of Cardiology, Department of Medicine III, Goethe University, Frankfurt, - Germany. -FAU - Zeiher, Andreas M -AU - Zeiher AM -FAU - Dimmeler, Stefanie -AU - Dimmeler S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Arterioscler Thromb Vasc Biol -JT - Arteriosclerosis, thrombosis, and vascular biology -JID - 9505803 -RN - 0 (Biomarkers) -RN - 0 (MicroRNAs) -SB - IM -MH - Biomarkers/blood -MH - Cardiovascular Diseases/*blood/*diagnosis -MH - Diabetes Mellitus/blood/diagnosis -MH - Heart Failure/blood/diagnosis -MH - Humans -MH - MicroRNAs/*blood -MH - Myocardial Infarction/blood/diagnosis -MH - Prognosis -EDAT- 2011/10/21 06:00 -MHDA- 2012/01/24 06:00 -CRDT- 2011/10/21 06:00 -PHST- 2011/10/21 06:00 [entrez] -PHST- 2011/10/21 06:00 [pubmed] -PHST- 2012/01/24 06:00 [medline] -AID - 00043605-201111000-00007 [pii] -AID - 10.1161/ATVBAHA.111.226696 [doi] -PST - ppublish -SO - Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2383-90. doi: - 10.1161/ATVBAHA.111.226696. - -PMID- 19202521 -OWN - NLM -STAT- MEDLINE -DCOM- 20090731 -LR - 20101118 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 57 -IP - 1 -DP - 2009 Feb -TI - Update on the management of atherosclerotic renal artery disease. -PG - 95-101 -AB - Typically involving the renal artery ostium or proximal segment of the renal - artery, atherosclerosis is the major cause of renal artery stenosis. While - commonly without direct clinical consequences, the presence of renal artery - atherosclerosis is associated with atherosclerotic disease in other vascular beds - and in some subjects may give rise to systemic hypertension, progressive renal - dysfunction and/or heart failure. Aggressive blood pressure control, - atherosclerotic risk factor modification and use of anti-platelet therapy are - indicated once diagnosed. The role for concomitant renal artery revascularization - remains unclear and the decision should be individualized depending on patient - preferences, co-morbidities, institutional expertise, and carefully weighed risks - and benefits. Ongoing trials including CORAL and ASTRAL will hopefully provide - critical evidence for or against this additive invasive strategy. -FAU - Fenstad, E R -AU - Fenstad ER -AD - Mayo Graduate School of Medicine, Department of Internal Medicine, Mayo Clinic, - Rochester, MN, USA. -FAU - Kane, G C -AU - Kane GC -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Angioplasty, Balloon, Coronary -MH - Angiotensin II Type 1 Receptor Blockers/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Atherosclerosis/*complications/epidemiology/physiopathology/*therapy -MH - Clinical Trials as Topic -MH - Disease Progression -MH - Drug Therapy, Combination -MH - Evidence-Based Medicine -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Hypertension, Renovascular/etiology/therapy -MH - Incidence -MH - Minnesota/epidemiology -MH - Prevalence -MH - Randomized Controlled Trials as Topic -MH - Renal Artery - Obstruction/complications/epidemiology/*etiology/physiopathology/*therapy -MH - Risk Factors -MH - Stents -MH - Treatment Outcome -RF - 36 -EDAT- 2009/02/10 09:00 -MHDA- 2009/08/01 09:00 -CRDT- 2009/02/10 09:00 -PHST- 2009/02/10 09:00 [entrez] -PHST- 2009/02/10 09:00 [pubmed] -PHST- 2009/08/01 09:00 [medline] -PST - ppublish -SO - Minerva Cardioangiol. 2009 Feb;57(1):95-101. - -PMID- 19273095 -OWN - NLM -STAT- MEDLINE -DCOM- 20090407 -LR - 20220228 -IS - 2768-6698 (Electronic) -IS - 2768-6698 (Linking) -VI - 14 -IP - 2 -DP - 2009 Jan 1 -TI - Vascular changes after cardiac surgery: role of NOS, COX, kinases, and growth - factors. -PG - 689-98 -AB - Cardiovascular disease remains the leading cause of mortality in the - industrialized world. Despite advances in pharmacotherapy and catheter based - interventions, coronary artery bypass grafting remains an essential therapeutic - modality. The majority of coronary artery bypass operations, as well as other - cardiac surgical procedures require the use of ischemic cardioplegic arrest and - cardiopulmonary bypass, both of which result in iatrogenic injury to the - vasculature and microcirculation. This injury can manifest as impaired - vasorelaxation or vasoconstriction, depending upon the organ system involved, - resulting in impaired tissue perfusion and the development of edema. Key to this - dysfunction are changes in the following: nitric oxide signaling secondary to - changes in eNOS and iNOS expression and activity, cyclooxygenase function with - increases in pro-inflammatory COX-2 activity, alterations in Protein Kinase C and - Mitogen Activated Protein Kinase signaling, and an increase in Vascular - Endothelial Growth Factor expression increasing vascular permeability and - dilatation. This review discusses our current understanding of cardioplegia and - cardiopulmonary bypass induced changes in the vasculature, and therapeutic - interventions aimed at modulating the altered signaling pathways. -FAU - Sodha, Neel R -AU - Sodha NR -AD - Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center and - Harvard Medical School, Boston, MA 02215. -FAU - Clements, Richard T -AU - Clements RT -FAU - Sellke, Frank W -AU - Sellke FW -LA - eng -GR - R01 HL046716/HL/NHLBI NIH HHS/United States -GR - T32 HL076130/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090101 -PL - Singapore -TA - Front Biosci (Landmark Ed) -JT - Frontiers in bioscience (Landmark edition) -JID - 101612996 -RN - 0 (Intercellular Signaling Peptides and Proteins) -RN - EC 1.14.13.39 (Nitric Oxide Synthase) -RN - EC 1.14.99.1 (Prostaglandin-Endoperoxide Synthases) -RN - EC 2.7.- (Protein Kinases) -SB - IM -MH - Blood Vessels/*physiopathology -MH - *Coronary Artery Bypass -MH - Heart Arrest, Induced -MH - Humans -MH - Intercellular Signaling Peptides and Proteins/*physiology -MH - Nitric Oxide Synthase/*physiology -MH - Prostaglandin-Endoperoxide Synthases/*physiology -MH - Protein Kinases/*physiology -PMC - PMC4771624 -MID - NIHMS759926 -COIS- The authors have no conflicts of interest relating to this work. -EDAT- 2009/03/11 09:00 -MHDA- 2009/04/08 09:00 -PMCR- 2016/03/01 -CRDT- 2009/03/11 09:00 -PHST- 2009/03/11 09:00 [entrez] -PHST- 2009/03/11 09:00 [pubmed] -PHST- 2009/04/08 09:00 [medline] -PHST- 2016/03/01 00:00 [pmc-release] -AID - 3273 [pii] -AID - 10.2741/3273 [doi] -PST - epublish -SO - Front Biosci (Landmark Ed). 2009 Jan 1;14(2):689-98. doi: 10.2741/3273. - -PMID- 24188221 -OWN - NLM -STAT- MEDLINE -DCOM- 20140527 -LR - 20131105 -IS - 1558-2264 (Electronic) -IS - 0733-8651 (Linking) -VI - 31 -IP - 4 -DP - 2013 Nov -TI - Cardiogenic shock. -PG - 567-80, viii -LID - S0733-8651(13)00072-6 [pii] -LID - 10.1016/j.ccl.2013.07.009 [doi] -AB - Cardiogenic shock (CS) is a condition in which a marked reduction in cardiac - output and inadequate end-organ perfusion results from an array of cardiac - insults, the most common of which is acute myocardial infarction. CS is a - systemic disease involving a vicious cycle of inflammation, ischemia, and - progressive myocardial dysfunction, which often results in death. This - life-threatening emergency requires intensive monitoring accompanied by - aggressive hemodynamic support; other therapies are tailored to the specific - pathophysiology. The development of novel therapeutic strategies is urgently - required to reduce the unacceptably high mortality rates currently associated - with CS. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Cooper, Howard A -AU - Cooper HA -AD - Coronary Care Unit, Medstar Heart Institute, Medstar Washington Hospital Center, - 110 Irving Street Northwest, Suite NA-1103, Washington, DC 20010, USA. Electronic - address: howard.a.cooper@medstar.net. -FAU - Panza, Julio A -AU - Panza JA -LA - eng -PT - Journal Article -PT - Review -DEP - 20130920 -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Assisted Circulation/methods -MH - Cardiovascular Agents/therapeutic use -MH - Coronary Care Units -MH - Extracorporeal Membrane Oxygenation -MH - Heart Rupture, Post-Infarction/diagnosis/surgery -MH - Heart-Assist Devices -MH - Hemodynamics/physiology -MH - Humans -MH - Myocardial Revascularization/methods -MH - Prognosis -MH - Randomized Controlled Trials as Topic -MH - Shock, Cardiogenic/diagnosis/etiology/*therapy -MH - Ventricular Dysfunction, Right/diagnosis/therapy -OTO - NOTNLM -OT - Acute myocardial infarction -OT - Cardiogenic shock -OT - Extracorporeal membrane oxygenation -OT - Inflammation -OT - Intra-aortic balloon pump -OT - Left ventricular assist device -OT - Prognosis -OT - Reperfusion -EDAT- 2013/11/06 06:00 -MHDA- 2014/05/28 06:00 -CRDT- 2013/11/06 06:00 -PHST- 2013/11/06 06:00 [entrez] -PHST- 2013/11/06 06:00 [pubmed] -PHST- 2014/05/28 06:00 [medline] -AID - S0733-8651(13)00072-6 [pii] -AID - 10.1016/j.ccl.2013.07.009 [doi] -PST - ppublish -SO - Cardiol Clin. 2013 Nov;31(4):567-80, viii. doi: 10.1016/j.ccl.2013.07.009. Epub - 2013 Sep 20. - -PMID- 19532103 -OWN - NLM -STAT- MEDLINE -DCOM- 20090924 -LR - 20090617 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 24 -IP - 2 -DP - 2009 Mar -TI - Management of left ventricular diastolic heart failure: is it only blood pressure - control? -PG - 161-6 -LID - 10.1097/HCO.0b013e328320d530 [doi] -AB - PURPOSE OF REVIEW: Diastolic heart failure (DHF) is the most common form of heart - failure (HF) seen by clinicians today in practice. With the increasing prevalence - of DHF, the need for greater spectrum of proven therapies in this condition is - clear. RECENT FINDINGS: There are few data available to guide the therapy of - these patients, and no treatment has been shown to improve survival in DHF. The - results of the Hong Kong DHF trial, the first comparative study between an - angiotensin converting enzyme inhibitor (ACEI) and an angiotensin receptor - blocker (ARB), again did not provide evidence for a superior effect of ACE - inhibitors or ARBs in patients with diastolic heart failure. SUMMARY: - Traditionally, treatments for congestive HF with decreased ejection fraction have - been used to treat DHS, without much proof of benefit. The high mortality and - morbidity of these patients underscore the urgent need to find ways to improve - outcomes for these patients. Consequently, the care of these patients should be - redirected toward screening and treatment of crucial comorbidities such as - hypertension, coronary artery disease, atrial fibrillation, obesity, diabetes, - and chronic kidney disease. -FAU - Koprowski, Andrzej -AU - Koprowski A -AD - Department of Cardiology, Medical University of Gdansk, Gdansk ul. Debinki 7, - Poland. -FAU - Gruchala, Marcin -AU - Gruchala M -FAU - Rynkiewicz, Andrzej -AU - Rynkiewicz A -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Antihypertensive Agents/therapeutic use -MH - Blood Pressure -MH - Heart Failure, Diastolic/diagnosis/epidemiology/*therapy -MH - Humans -MH - Ventricular Dysfunction, Left/*therapy -RF - 38 -EDAT- 2009/06/18 09:00 -MHDA- 2009/09/25 06:00 -CRDT- 2009/06/18 09:00 -PHST- 2009/06/18 09:00 [entrez] -PHST- 2009/06/18 09:00 [pubmed] -PHST- 2009/09/25 06:00 [medline] -AID - 00001573-200903000-00012 [pii] -AID - 10.1097/HCO.0b013e328320d530 [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2009 Mar;24(2):161-6. doi: 10.1097/HCO.0b013e328320d530. - -PMID- 18819236 -OWN - NLM -STAT- MEDLINE -DCOM- 20081022 -LR - 20080929 -IS - 0002-838X (Print) -IS - 0002-838X (Linking) -VI - 78 -IP - 6 -DP - 2008 Sep 15 -TI - Aortic stenosis: diagnosis and treatment. -PG - 717-24 -AB - Aortic stenosis is the most important cardiac valve disease in developed - countries, affecting 3 percent of persons older than 65 years. Although the - survival rate in asymptomatic patients with aortic stenosis is comparable to that - in age- and sex-matched control patients, the average overall survival rate in - symptomatic persons without aortic valve replacement is two to three years. - During the asymptomatic latent period, left ventricular hypertrophy and atrial - augmentation of preload compensate for the increase in afterload caused by aortic - stenosis. As the disease worsens, these compensatory mechanisms become - inadequate, leading to symptoms of heart failure, angina, or syncope. Aortic - valve replacement should be recommended in most patients with any of these - symptoms accompanied by evidence of significant aortic stenosis on - echocardiography. Watchful waiting is recommended for most asymptomatic patients, - including those with hemodynamically significant aortic stenosis. Patients should - be educated about symptoms and the importance of promptly reporting them to their - physicians. Serial Doppler echocardiography is recommended annually for severe - aortic stenosis, every one or two years for moderate disease, and every three to - five years for mild disease. Cardiology referral is recommended for all patients - with symptomatic aortic stenosis, those with severe aortic stenosis without - apparent symptoms, and those with left ventricular dysfunction. Many patients - with asymptomatic aortic stenosis have concurrent cardiac conditions, such as - hypertension, atrial fibrillation, and coronary artery disease, which should also - be carefully managed. -FAU - Grimard, Brian H -AU - Grimard BH -AD - Mayo Clinic, St. Augustine, FL 32086, USA. grimard.brian@mayo.edu -FAU - Larson, Jan M -AU - Larson JM -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am Fam Physician -JT - American family physician -JID - 1272646 -SB - IM -MH - Aortic Valve Stenosis/*diagnosis/etiology/*therapy -MH - Decision Trees -MH - Heart Function Tests -MH - Humans -RF - 46 -EDAT- 2008/09/30 09:00 -MHDA- 2008/10/23 09:00 -CRDT- 2008/09/30 09:00 -PHST- 2008/09/30 09:00 [pubmed] -PHST- 2008/10/23 09:00 [medline] -PHST- 2008/09/30 09:00 [entrez] -PST - ppublish -SO - Am Fam Physician. 2008 Sep 15;78(6):717-24. - -PMID- 19160223 -OWN - NLM -STAT- MEDLINE -DCOM- 20090319 -LR - 20250623 -IS - 1469-493X (Electronic) -IS - 1361-6137 (Linking) -IP - 1 -DP - 2009 Jan 21 -TI - Transmyocardial laser revascularization versus medical therapy for refractory - angina. -PG - CD003712 -LID - 10.1002/14651858.CD003712.pub2 [doi] -AB - BACKGROUND: Chronic angina and advanced forms of coronary disease are - increasingly more frequent. Although the improved efficacy of available - revascularization treatments, a subgroup of patients present with refractory - angina. Transmyocardial laser revascularization (TMLR) has been proposed to - improve the clinical situation of these patients. OBJECTIVES: To assess the - efficacy and safety of TMLR versus optimal medical treatment in patients with - refractory angina in alleviating the severity of angina and improving - survivorship and heart function. SEARCH STRATEGY: We searched the Cochrane - Central Register of Controlled Trials on The Cochrane Library (Issue 2 2007), - MEDLINE (January 2006 to June 2007), EMBASE ( 2004 to June 2007) and ongoing - studies were sought using the metaRegister of Controlled Trials database (mRCT) - and ClinicalTrials.gov databases. No languages restrictions were applied. - Reference lists of relevant papers were also checked. SELECTION CRITERIA: Studies - were selected if they fulfilled the following criteria: randomized controlled - trials of TMLR, by thoracotomy, in patients with angina grade III-IV who were - excluded from other revascularization procedures. From a total of 181 references, - 20 papers were selected, reporting data from seven studies. DATA COLLECTION AND - ANALYSIS: Two reviewers abstracted data from selected papers; . The reviewers - performed independently both quality assessment and data extraction. Selected - studies present methodological weaknesses. None of them fulfilled all the quality - criteria. MAIN RESULTS: Seven studies (1137 participants of which 559 randomized - to TMLR) were included. Overall, 43.8 % of patients in the treatment group - decreased two angina classes as compared with 14.8 % in the control group, odds - ratio (OR) of 4.63 (95% confidence interval (CI) 3.43 to 6.25), and heterogeneity - was statistically significant. Mortality by intention-to-treat analysis at both - 30 days (4.0 % in the TMLR group and 3.5 % in the control group) and 1 year (12.2 - % in the TMLR group and 11.9 % in the control group) was similar in both groups. - The 30-days mortality as treated was 6.8% in TMLR group and 0.8% in the control - group, showing a statistically significant difference. The pooled OR was 3.76 - (95% CI 1.63 to 8.66), because of the higher mortality in patients crossing from - standard treatment to TMLR. AUTHORS' CONCLUSIONS: There is insufficient evidence - to conclude that the clinical benefits of TMLR outweigh the potential risks. The - procedure is associated with a significant early mortality. -FAU - Briones, Eduardo -AU - Briones E -AD - Quality and Health Information , Valme University Hospital, Avda Bellavista s.n., - Sevilla, Spain, 41014. eduardo.briones.sspa@juntadeandalucia.es -FAU - Lacalle, Juan Ramon -AU - Lacalle JR -FAU - Marin, Ignacio -AU - Marin I -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -DEP - 20090121 -PL - England -TA - Cochrane Database Syst Rev -JT - The Cochrane database of systematic reviews -JID - 100909747 -SB - IM -UIN - Cochrane Database Syst Rev. 2015 Feb 27;(2):CD003712. doi: - 10.1002/14651858.CD003712.pub3. PMID: 25721946 -MH - Angina Pectoris/mortality/*therapy -MH - Humans -MH - Laser Therapy/*methods -MH - Myocardial Revascularization/*methods -MH - Randomized Controlled Trials as Topic -RF - 61 -EDAT- 2009/01/23 09:00 -MHDA- 2009/03/20 09:00 -CRDT- 2009/01/23 09:00 -PHST- 2009/01/23 09:00 [entrez] -PHST- 2009/01/23 09:00 [pubmed] -PHST- 2009/03/20 09:00 [medline] -AID - 10.1002/14651858.CD003712.pub2 [doi] -PST - epublish -SO - Cochrane Database Syst Rev. 2009 Jan 21;(1):CD003712. doi: - 10.1002/14651858.CD003712.pub2. - -PMID- 21228716 -OWN - NLM -STAT- MEDLINE -DCOM- 20110422 -LR - 20201216 -IS - 1558-2035 (Electronic) -IS - 1558-2027 (Linking) -VI - 12 -IP - 2 -DP - 2011 Feb -TI - Stable angina in women: lessons from the National Heart, Lung and Blood - Institute-sponsored Women’s Ischemia Syndrome Evaluation. -PG - 85-7 -LID - 10.2459/JCM.0b013e3283430969 [doi] -AB - The paradoxical sex difference in which women have lower rates of anatomical - coronary artery disease (CAD) but worsening symptoms, ischemia, and outcomes - appears to be linked to a sex-specific pathophysiology of coronary reactivity, - which includes microvascular dysfunction. For women with obstructive CAD, their - risk is elevated compared with men, yet women are less likely to receive - guideline-indicated therapies. For women with evidence of ischemia but no - obstructive CAD, antianginal and antiischemic therapies can ameliorate symptoms, - improve endothelial function and quality of life; however, trials aimed to - improve outcomes are needed. Thus, ischemic heart disease (IHD) in women presents - a unique and difficult challenge for clinicians due to a greater symptom burden, - functional disability, higher healthcare costs, and more adverse outcomes as - compared with men, despite a lower prevalence and severity of obstructive CAD, - which remains the current focus of therapeutic strategies. Continued research is - indicated to devise therapeutic regimens to improve symptom burden and reduce - risk in women with IHD. -CI - 2011 Italian Federation of Cardiology. -FAU - Merz, C Noel Bairey -AU - Merz CN -AD - Women’s Heart Center, Heart Institute, Cedars-Sinai Medical Center, Los Angeles, - California, USA. merz@cshs.org -FAU - Shaw, Leslee J -AU - Shaw LJ -LA - eng -GR - MO1-RR00425/RR/NCRR NIH HHS/United States -GR - N01-HV-68161/HV/NHLBI NIH HHS/United States -GR - N01-HV-68162/HV/NHLBI NIH HHS/United States -GR - N01-HV-68163/HV/NHLBI NIH HHS/United States -GR - N01-HV-68164/HV/NHLBI NIH HHS/United States -GR - R01 HL090957-01A1/HL/NHLBI NIH HHS/United States -GR - R03 AG032631-01/AG/NIA NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Cardiovasc Med (Hagerstown) -JT - Journal of cardiovascular medicine (Hagerstown, Md.) -JID - 101259752 -SB - IM -MH - Angina Pectoris/diagnosis/*epidemiology/etiology/therapy -MH - Evidence-Based Medicine -MH - Female -MH - Health Status Disparities -MH - Healthcare Disparities -MH - Humans -MH - Male -MH - Myocardial Ischemia/complications/diagnosis/*epidemiology/therapy -MH - *National Heart, Lung, and Blood Institute (U.S.) -MH - Prognosis -MH - Risk Assessment -MH - Risk Factors -MH - Sex Factors -MH - United States -MH - *Women's Health -EDAT- 2011/01/14 06:00 -MHDA- 2011/04/26 06:00 -CRDT- 2011/01/14 06:00 -PHST- 2011/01/14 06:00 [entrez] -PHST- 2011/01/14 06:00 [pubmed] -PHST- 2011/04/26 06:00 [medline] -AID - 10.2459/JCM.0b013e3283430969 [doi] -PST - ppublish -SO - J Cardiovasc Med (Hagerstown). 2011 Feb;12(2):85-7. doi: - 10.2459/JCM.0b013e3283430969. - -PMID- 22292873 -OWN - NLM -STAT- MEDLINE -DCOM- 20120525 -LR - 20151119 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Linking) -VI - 10 -IP - 2 -DP - 2012 Feb -TI - Are endothelial progenitor cells a prognostic factor in patients with heart - failure? -PG - 167-75 -LID - 10.1586/erc.11.178 [doi] -AB - For the last two decades, endothelial progenitor cells (EPCs) have been proposed - as a novel prognostic marker and potential therapeutic target in patients with - cardiovascular diseases. EPCs are involved in the process of adult vasculogenesis - and repair of dysfunctional endothelium. Endothelial dysfunction has been - documented in the peripheral and coronary arteries of chronic heart failure (HF) - patients, and has proved to be an independent predictor of morbidity and - mortality in HF patients. This has led researchers to analyze the association of - EPCs and disease severity in HF patients. In this paper, we review studies - analyzing the prognostic role of EPCs in patients with HF. Through a systematic - search, we identified 14 relevant studies. Only one study analyzed mortality as - an outcome; the others evaluated the association between EPC levels and patients' - characteristics. Overall, results were inconsistent and suggested that levels of - EPCs may vary according to factors such as disease severity, underlying cause of - cardiomyopathy and medical therapy. -FAU - Alba, Ana Carolina -AU - Alba AC -AD - Heart Failure/Transplant Program, Toronto General Hospital, University Health - Network, Toronto, Ontario, Canada. carolina.alba@uhn.ca -FAU - Delgado, Diego Hernan -AU - Delgado DH -FAU - Rao, Vivek -AU - Rao V -FAU - Walter, Stephen -AU - Walter S -FAU - Guyatt, Gordon -AU - Guyatt G -FAU - Ross, Heather Joan -AU - Ross HJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -RN - 0 (Biomarkers) -SB - IM -MH - Adult -MH - Animals -MH - Biomarkers/metabolism -MH - Endothelial Cells/metabolism -MH - Endothelium, Vascular/cytology/*pathology -MH - Heart Failure/*physiopathology/therapy -MH - Humans -MH - Prognosis -MH - Severity of Illness Index -MH - Stem Cells/*metabolism -EDAT- 2012/02/02 06:00 -MHDA- 2012/05/26 06:00 -CRDT- 2012/02/02 06:00 -PHST- 2012/02/02 06:00 [entrez] -PHST- 2012/02/02 06:00 [pubmed] -PHST- 2012/05/26 06:00 [medline] -AID - 10.1586/erc.11.178 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2012 Feb;10(2):167-75. doi: 10.1586/erc.11.178. - -PMID- 18703404 -OWN - NLM -STAT- MEDLINE -DCOM- 20080919 -LR - 20160518 -IS - 1937-6448 (Print) -IS - 1937-6448 (Linking) -VI - 268 -DP - 2008 -TI - Natriuretic peptides in vascular physiology and pathology. -PG - 59-93 -LID - 10.1016/S1937-6448(08)00803-4 [doi] -AB - Four major natriuretic peptides have been isolated: atrial natriuretic peptide - (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), and - Dendroaspis-type natriuretic peptide (DNP). Natriuretic peptides play an - important role in the regulation of cardiovascular homeostasis maintaining blood - pressure and extracellular fluid volume. The classical endocrine effects of - natriuretic peptides to modulate fluid and electrolyte balance and vascular - smooth muscle tone are complemented by autocrine and paracrine actions that - include regulation of coronary blood flow and, therefore, myocardial perfusion; - modulation of proliferative responses during myocardial and vascular remodeling; - and cytoprotective anti-ischemic effects. The actions of natriuretic peptides are - mediated by the specific binding of these peptides to three cell surface - receptors: type A natriuretic peptide receptor (NPR-A), type B natriuretic - peptide receptor (NPR-B), and type C natriuretic peptide receptor (NPR-C). NPR-A - and NPR-B are guanylyl cyclase receptors that increase intracellular cGMP - concentration and activate cGMP-dependent protein kinases. NPR-C has been - presented as a clearance receptor and its activation also results in inhibition - of adenylyl cyclase activity. The wide range of effects of natriuretic peptides - might be the base for the development of new therapeutic strategies of great - benefit in patients with cardiovascular problems including coronary artery - disease or heart failure. This review summarizes current literature concerning - natriuretic peptides, their receptors and their effects on fluid/electrolyte - balance, and vascular and cardiac physiology and pathology, including primary - hypertension and myocardial infarction. In addition, we will attempt to provide - an update on important issues regarding natriuretic peptides in congestive heart - failure. -FAU - Woodard, Geoffrey E -AU - Woodard GE -AD - National Institute of Allergy and Infectious Diseases, MSC 1876, Bethesda, - Maryland 20892-1876, USA. -FAU - Rosado, Juan A -AU - Rosado JA -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Int Rev Cell Mol Biol -JT - International review of cell and molecular biology -JID - 101475846 -RN - 0 (Natriuretic Peptides) -RN - 0 (Receptors, Peptide) -SB - IM -MH - Animals -MH - Blood Vessels/*pathology/*physiology -MH - Cell Proliferation -MH - Heart/physiology -MH - Humans -MH - Hypertension/physiopathology -MH - Models, Cardiovascular -MH - Myocardium/pathology -MH - Natriuretic Peptides/*physiology -MH - Oxidative Stress -MH - Receptors, Peptide/physiology -MH - Signal Transduction -RF - 204 -EDAT- 2008/08/16 09:00 -MHDA- 2008/09/20 09:00 -CRDT- 2008/08/16 09:00 -PHST- 2008/08/16 09:00 [pubmed] -PHST- 2008/09/20 09:00 [medline] -PHST- 2008/08/16 09:00 [entrez] -AID - S1937-6448(08)00803-4 [pii] -AID - 10.1016/S1937-6448(08)00803-4 [doi] -PST - ppublish -SO - Int Rev Cell Mol Biol. 2008;268:59-93. doi: 10.1016/S1937-6448(08)00803-4. - -PMID- 17651841 -OWN - NLM -STAT- MEDLINE -DCOM- 20080325 -LR - 20250623 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 124 -IP - 3 -DP - 2008 Mar 14 -TI - Takotsubo cardiomyopathy or transient left ventricular apical ballooning - syndrome: A systematic review. -PG - 283-92 -AB - BACKGROUND: Transient left ventricular apical ballooning syndrome (TLVABS) is an - acute cardiac syndrome mimicking ST-segment elevation myocardial infarction - characterized by transient wall-motion abnormalities involving apical and - mid-portions of the left ventricle in the absence of significant obstructive - coronary disease. METHODS: Searching the MEDLINE database 28 case series met the - eligibility criteria and were summarized in a narrative synthesis of the - demographic characteristics, clinical features and pathophysiological mechanisms. - RESULTS: TLVABS is observed in 0.7-2.5% of patients with suspected ACS, affects - women in 90.7% (95% CI: 88.2-93.2%) with a mean age ranging from 62 to 76 years - and most commonly presents with chest pain (83.4%, 95% CI: 80.0-86.7%) and - dyspnea (20.4%, 95% CI: 16.3-24.5%) following an emotionally or physically - stressful event. ECG on admission shows ST-segment elevations in 71.1% (95% CI: - 67.2-75.1%) and is accompanied by usually mild elevations of Troponins in 85.0% - (95% CI: 80.8-89.1%). Despite dramatic clinical presentation and substantial risk - of heart failure, cardiogenic shock and arrhythmias, LVEF improved from 20-49.9% - to 59-76% within a mean time of 7-37 days with an in-hospital mortality rate of - 1.7% (95% CI: 0.5-2.8%), complete recovery in 95.9% (95% CI: 93.8-98.1%) and rare - recurrence. The underlying etiology is thought to be based on an exaggerated - sympathetic stimulation. CONCLUSION: TLVABS is a considerable differential - diagnosis in ACS, especially in postmenopausal women with a preceding stressful - event. Data on longterm follow-up is pending and further studies will be - necessary to clarify the etiology and reach consensus in acute and longterm - management of TLVABS. -FAU - Pilgrim, Thomas M -AU - Pilgrim TM -AD - Department of Medicine, Maimonides Medical Center, Brooklyn, New York, USA. - pilgrimthomas@hotmail.com -FAU - Wyss, Thomas R -AU - Wyss TR -LA - eng -PT - Journal Article -PT - Systematic Review -DEP - 20070724 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -SB - IM -CIN - Int J Cardiol. 2009 May 29;134(3):e132-4. doi: 10.1016/j.ijcard.2008.01.055. - PMID: 18562025 -MH - Diagnosis, Differential -MH - Echocardiography -MH - Electrocardiography -MH - Humans -MH - Magnetic Resonance Imaging -MH - Myocardial Contraction -MH - Myocardial Infarction/diagnosis -MH - Stroke Volume -MH - Syndrome -MH - Takotsubo Cardiomyopathy/complications/*diagnosis/physiopathology -MH - Tomography, Emission-Computed, Single-Photon -MH - Ventricular Dysfunction, Left/*diagnosis/etiology/physiopathology -RF - 69 -EDAT- 2007/07/27 09:00 -MHDA- 2008/03/26 09:00 -CRDT- 2007/07/27 09:00 -PHST- 2007/05/30 00:00 [received] -PHST- 2007/07/01 00:00 [accepted] -PHST- 2007/07/27 09:00 [pubmed] -PHST- 2008/03/26 09:00 [medline] -PHST- 2007/07/27 09:00 [entrez] -AID - S0167-5273(07)01064-9 [pii] -AID - 10.1016/j.ijcard.2007.07.002 [doi] -PST - ppublish -SO - Int J Cardiol. 2008 Mar 14;124(3):283-92. doi: 10.1016/j.ijcard.2007.07.002. Epub - 2007 Jul 24. - -PMID- 17414579 -OWN - NLM -STAT- MEDLINE -DCOM- 20070525 -LR - 20121115 -IS - 1075-2765 (Print) -IS - 1075-2765 (Linking) -VI - 14 -IP - 2 -DP - 2007 Mar-Apr -TI - The future of antihypertensive treatment. -PG - 121-34 -AB - Despite progress in recent years in the prevention, detection, and treatment of - high blood pressure (BP), hypertension remains an important public health - challenge. Hypertension affects approximately 1 billion individuals worldwide. - High BP is associated with an increased risk of mortality and morbidity from - stroke, coronary heart disease, congestive heart failure, and end-stage renal - disease; it also has a negative impact on the quality of life. Hypertension - cannot be eliminated because there are no vaccines to prevent the development of - hypertension, but, its incidence can be decreased by reducing the risk factors - for its development, which include obesity, high dietary intake of fat and sodium - and low intake of potassium, physical inactivity, smoking, and excessive alcohol - intake. For established hypertension, efforts are to be directed to control BP by - lifestyle modification (LSM). However, if BP cannot be adequately controlled with - LSM, then pharmacotherapy can be instituted along with LSM. Normalization of BP - reduces cardiovascular risk (for cardiovascular death, myocardial infarction, and - cardiac arrest), provides renoprotection (prevention of the onset or slowing of - proteinuria and progression of renal dysfunction to end-stage renal disease in - patients with hypertension, diabetes mellitus types 1 and 2, and chronic renal - disease), and decreases the risk of cerebrovascular events (stroke and cognition - impairment), as has been amply demonstrated by a large number of randomized - clinical trials. In spite of the availability of more than 75 antihypertensive - agents in 9 classes, BP control in the general population is at best inadequate. - Therefore, antihypertensive therapy in the future or near future should be - directed toward improving BP control in treated hypertensive patients with the - available drugs by using the right combinations at optimum doses, individually - tailored gene-polymorphism directed therapy, or development of new modalities - such as gene therapy and vaccines. Several studies have shown that BP can be - reduced by lifestyle/behavior modification. Although, the reductions appear to be - trivial, even small reductions in systolic BP (for example, 3-5 mm Hg) produce - dramatic reduction in adverse cardiac events and stroke. On the basis of the - results of clinical and clinical/observational studies, it has been recommended - that more emphasis be placed on lifestyle/behavior modification (obesity, high - dietary intake of fat and sodium, physical inactivity, smoking, excessive alcohol - intake, low dietary potassium intake) to control BP and also to improve the - efficacy of pharmacologic treatment of high BP. New classes of antihypertensive - drugs and new compounds in the established drug classes are likely to widen the - armamentarium available to combat hypertension. These include the aldosterone - receptor blockers, vasodilator beta-blockers, renin inhibitors, endothelin - receptor antagonists, and dual endopeptidase inhibitors. The use of fixed-dose - combination drug therapy is likely to increase. There is a conceptual possibility - that gene therapy may yield long-lasting antihypertensive effects by influencing - the genes associated with hypertension. But, the treatment of human essential - hypertension requires sustained over-expression of genes. Some of the challenging - tasks for successful gene therapy that need to be mastered include identification - of target genes, ideal gene transfer vector, precise delivery of genes into the - required site (target), efficient transfer of genes into the cells of the target, - and prompt assessment of gene expression over time. Targeting the RAS by - antisense gene therapy appears to be a viable strategy for the long-term control - of hypertension. Several problems that are encountered in the delivery of gene - therapy include 1) low efficiency for gene transfer into vascular cells; 2) a - lack of selectivity; 3) problem in determining how to prolong and control - transgene expression or antisense inhibition; and 4) difficulty in minimizing the - adverse effects of viral or nonviral vectors. In spite of the hurdles that face - gene therapy administration in humans, studies in animals indicate that gene - therapy may be feasible in treating human hypertension, albeit not in the near - future. DNA testing for genetic polymorphism and determining the genotype of a - patient may predict response to a certain class of antihypertensive agent and - thus optimize therapy in individual patients. In this regard, there are some - studies that report the effectiveness of antihypertensive therapy based upon the - genotype of selected patients. Treatment of human hypertension with vaccines is - feasible but is not likely to be available in the near future. -FAU - Israili, Zafar H -AU - Israili ZH -AD - Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, - USA. zisrail@emory.edu -FAU - Hernández-Hernández, Rafael -AU - Hernández-Hernández R -FAU - Valasco, Manuel -AU - Valasco M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Ther -JT - American journal of therapeutics -JID - 9441347 -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Antihypertensive Agents/administration & dosage/therapeutic use -MH - Complementary Therapies/methods -MH - Drug Therapy, Combination -MH - Genetic Therapy/methods -MH - Health Behavior -MH - Humans -MH - Hypertension/drug therapy/prevention & control/*therapy -MH - Immunotherapy -MH - Life Style -MH - Polymorphism, Genetic -RF - 164 -EDAT- 2007/04/07 09:00 -MHDA- 2007/05/26 09:00 -CRDT- 2007/04/07 09:00 -PHST- 2007/04/07 09:00 [pubmed] -PHST- 2007/05/26 09:00 [medline] -PHST- 2007/04/07 09:00 [entrez] -AID - 00045391-200703000-00003 [pii] -AID - 10.1097/01.pap.0000249915.12185.58 [doi] -PST - ppublish -SO - Am J Ther. 2007 Mar-Apr;14(2):121-34. doi: 10.1097/01.pap.0000249915.12185.58. - -PMID- 16644235 -OWN - NLM -STAT- MEDLINE -DCOM- 20060731 -LR - 20181201 -IS - 1043-6618 (Print) -IS - 1043-6618 (Linking) -VI - 53 -IP - 5 -DP - 2006 May -TI - Anti-ischaemic effect of ivabradine. -PG - 435-9 -AB - Ivabradine, the first representative of a new class of exclusive heart - rate-reducing agents, selectively inhibits the I(f) current in the sinoatrial - node. The direct electrophysiological consequence of this inhibition is a - reduction in the slope of the diastolic depolarisation curve and a decrease in - heart rate. Pharmacological inhibition of the I(f) current with ivabradine has - been shown to preserve coronary vasodilatation upon exercise, i.e., myocardial - perfusion, with no negative inotropic effects and maintenance of cardiac - contractility. Ivabradine protects the myocardium during ischaemia, improves left - ventricular function in congestive heart failure, and reduces remodelling - subsequent to myocardial infarction. Pure heart rate reduction by specific and - selective I(f) inhibition decreases oxygen demand, improves myocardial energetics - and improves perfusion of the ischaemic myocardium. We can expect distinct - clinical benefits from long-term heart rate reduction in patients with chronic - ischaemic disease. -FAU - Ferrari, Roberto -AU - Ferrari R -AD - University of Ferrara, Italy. fri@dns.unife.it -FAU - Cargnoni, Anna -AU - Cargnoni A -FAU - Ceconi, Claudio -AU - Ceconi C -LA - eng -PT - Journal Article -PT - Review -DEP - 20060328 -PL - Netherlands -TA - Pharmacol Res -JT - Pharmacological research -JID - 8907422 -RN - 0 (Benzazepines) -RN - 0 (Ion Channels) -RN - 3H48L0LPZQ (Ivabradine) -SB - IM -MH - Animals -MH - Benzazepines/pharmacology/*therapeutic use -MH - Cardiomyopathies/*drug therapy/physiopathology -MH - Depression, Chemical -MH - Heart Rate/*drug effects -MH - Humans -MH - Ion Channels/*antagonists & inhibitors -MH - Ivabradine -RF - 31 -EDAT- 2006/04/29 09:00 -MHDA- 2006/08/01 09:00 -CRDT- 2006/04/29 09:00 -PHST- 2006/02/02 00:00 [received] -PHST- 2006/02/13 00:00 [revised] -PHST- 2006/03/10 00:00 [accepted] -PHST- 2006/04/29 09:00 [pubmed] -PHST- 2006/08/01 09:00 [medline] -PHST- 2006/04/29 09:00 [entrez] -AID - S1043-6618(06)00057-0 [pii] -AID - 10.1016/j.phrs.2006.03.018 [doi] -PST - ppublish -SO - Pharmacol Res. 2006 May;53(5):435-9. doi: 10.1016/j.phrs.2006.03.018. Epub 2006 - Mar 28. - -PMID- 18953277 -OWN - NLM -STAT- MEDLINE -DCOM- 20081113 -LR - 20081027 -IS - 1530-6550 (Print) -IS - 1530-6550 (Linking) -VI - 9 -IP - 3 -DP - 2008 Summer -TI - Cardiac magnetic resonance: physics, pulse sequences, and clinical applications. -PG - 174-86 -AB - Cardiac magnetic resonance (CMR) is a new and promising technique for image-based - diagnosis in patients with known or suspected diseases of the heart. CMR allows - clinicians to obtain relevant information on anatomy, function, perfusion, and - viability of the myocardium. This technique offers the advantages of versatility, - lack of ionizing radiation, and superior soft tissue contrast. The variety of - clinical conditions that can affect the heart and the need to understand the - time-varying movement of the heart in 3 dimensions adds challenges to - interpretation of CMR above and beyond those present in understanding the imaging - modality itself. The image intensities present in CMR scans can vary by orders of - magnitude in the same subject depending on parameters set by the individual - acquiring the data. These different appearances of images may reflect distinct - pathophysiologic states and, therefore, an understanding of image acquisition is - fundamental to the clinical diagnosis and assessment of disease. -FAU - Fieno, David S -AU - Fieno DS -AD - Cedars-Sinai Medical Center, Department of Internal Medicine, Los Angeles, - California, USA. -LA - eng -PT - Journal Article -PT - Review -PL - Singapore -TA - Rev Cardiovasc Med -JT - Reviews in cardiovascular medicine -JID - 100960007 -SB - IM -MH - Cell Survival -MH - Coronary Circulation -MH - Heart Diseases/*pathology/physiopathology -MH - Humans -MH - Image Interpretation, Computer-Assisted -MH - Imaging, Three-Dimensional -MH - *Magnetic Resonance Imaging/methods -MH - Myocardium/*pathology -MH - Predictive Value of Tests -RF - 55 -EDAT- 2008/10/28 09:00 -MHDA- 2008/11/14 09:00 -CRDT- 2008/10/28 09:00 -PHST- 2008/10/28 09:00 [pubmed] -PHST- 2008/11/14 09:00 [medline] -PHST- 2008/10/28 09:00 [entrez] -PST - ppublish -SO - Rev Cardiovasc Med. 2008 Summer;9(3):174-86. - -PMID- 16788333 -OWN - NLM -STAT- MEDLINE -DCOM- 20060726 -LR - 20071115 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 14 -IP - 4 -DP - 2006 Jul-Aug -TI - Cardiovascular effects of erythropoietin: anemia and beyond. -PG - 200-4 -AB - We did a PubMed and Cochrane Database System review of different studies on the - diverse effects of erythropoietin (EPO), focusing mainly on the cardiovascular - system. The direct erythropoietic action of EPO is well studied and widely used. - Published studies report dramatic improvement in the course of heart failure with - EPO treatment. New controlled clinical trials on large and diverse groups of - patients are warranted. Antiapoptotic effects of EPO are newly discovered, - opening new horizons in both clinical investigation and therapy. The salvage of - cardiomyocytes in acute coronary syndromes, limiting the size of myocardial - infarction and improving functional recovery, is only one of multiple potential - applications of this effect. Derivatives of EPO with selective antiapoptotic - properties seem to hold the best prospects for future studies. Heart failure and - ischemic heart disease are potential areas where adding EPO to the conventional - treatment may be beneficial. -FAU - Guglin, Maya E -AU - Guglin ME -AD - Wayne State University/Detroit Medical Center/John D. Dingell VA Medical Center, - Detroit, Michigan, USA. meguglin@prodigy.net -FAU - Koul, Deepak -AU - Koul D -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 11096-26-7 (Erythropoietin) -SB - IM -MH - Anemia/*complications -MH - Animals -MH - Cardiovascular Diseases/*complications/*drug therapy -MH - Erythropoietin/pharmacology/*therapeutic use -MH - Heart Failure/complications/drug therapy -MH - Humans -MH - Myocardial Ischemia/complications/drug therapy -RF - 49 -EDAT- 2006/06/22 09:00 -MHDA- 2006/07/27 09:00 -CRDT- 2006/06/22 09:00 -PHST- 2006/06/22 09:00 [pubmed] -PHST- 2006/07/27 09:00 [medline] -PHST- 2006/06/22 09:00 [entrez] -AID - 00045415-200607000-00011 [pii] -AID - 10.1097/01.crd.0000195223.85556.8e [doi] -PST - ppublish -SO - Cardiol Rev. 2006 Jul-Aug;14(4):200-4. doi: 10.1097/01.crd.0000195223.85556.8e. - -PMID- 18955392 -OWN - NLM -STAT- MEDLINE -DCOM- 20090210 -LR - 20081028 -IS - 1532-2092 (Electronic) -IS - 1099-5129 (Linking) -VI - 10 Suppl 3 -DP - 2008 Nov -TI - Effects of CRT on myocardial innervation, perfusion and metabolism. -PG - iii114-7 -LID - 10.1093/europace/eun228 [doi] -AB - Heart failure leads to specific changes in cardiac perfusion, metabolism, and - innervation. Typically, in the early phase of heart failure, left ventricular - (LV) efficiency of forward work is compromised and right ventricular oxidative - metabolism increased while resting myocardial perfusion is normal. With advancing - disease, LV perfusion and especially the perfusion reserve and oxidative - metabolism also become compromised. In addition to the abnormalities linked with - the heart failure itself, commonly co-existing left bundle branch block leads to - striking, mainly regional imbalance in these parameters. Recent studies have - documented that cardiac resynchronization therapy (CRT) has prominent effects on - myocardial perfusion, metabolism, and innervation. Cardiac resynchronization - therapy normalizes many of these parameters and these changes can be considered - to be the signs of successful resynchronization. In contrast, a significant - number of patients do not respond to CRT. Some of the metabolic parameters, such - as existing glucose metabolism as a marker of viability as well as those related - to right ventricle function, may also be linked to the response to CRT. -FAU - Ukkonen, Heikki -AU - Ukkonen H -AD - 1Department of Medicine, Turku University Central Hospital, Turku, Finland. -FAU - Sundell, Jan -AU - Sundell J -FAU - Knuuti, Juhani -AU - Knuuti J -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Europace -JT - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal - of the working groups on cardiac pacing, arrhythmias, and cardiac cellular - electrophysiology of the European Society of Cardiology -JID - 100883649 -SB - IM -MH - Adaptation, Physiological -MH - *Cardiac Pacing, Artificial -MH - *Coronary Circulation -MH - Heart/*innervation/*physiopathology -MH - Humans -RF - 26 -EDAT- 2008/11/05 09:00 -MHDA- 2009/02/12 09:00 -CRDT- 2008/11/05 09:00 -PHST- 2008/11/05 09:00 [pubmed] -PHST- 2009/02/12 09:00 [medline] -PHST- 2008/11/05 09:00 [entrez] -AID - eun228 [pii] -AID - 10.1093/europace/eun228 [doi] -PST - ppublish -SO - Europace. 2008 Nov;10 Suppl 3:iii114-7. doi: 10.1093/europace/eun228. - -PMID- 22548810 -OWN - NLM -STAT- MEDLINE -DCOM- 20120716 -LR - 20120502 -IS - 1558-2264 (Electronic) -IS - 0733-8651 (Linking) -VI - 30 -IP - 2 -DP - 2012 May -TI - Anatomy and physiology of the right ventricle. -PG - 167-87 -LID - 10.1016/j.ccl.2012.03.009 [doi] -AB - Under normal baseline conditions the unique anatomy, myocardial ultrastructure, - and coronary physiology of the right ventricle (RV) reflect a high-volume - low-pressure pump. Early work described the RV as a passive conduit with minimal - pumping capability. It is now appreciated that through a mechanism of ventricular - interdependence, RV systolic function and diastolic load are extremely important - in the prognosis and treatment of congestive heart failure, cardiac - transplantation, pulmonary hypertension, congenital heart disease, and left - ventricle assist devices. Magnetic resonance imaging with three-dimensional - analysis has shown the complex geometry of the RV and the interaction of both - ventricles within the pericardium. -CI - Copyright © 2012. Published by Elsevier Inc. -FAU - Dell'Italia, Louis J -AU - Dell'Italia LJ -AD - Division of Cardiovascular Disease, Birmingham VA Medical Center, Birmingham, AL - 35294, USA. loudell@uab.edu -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -SB - IM -MH - Animals -MH - Blood Pressure/physiology -MH - Cardiac Volume/physiology -MH - Diastole/physiology -MH - Dogs -MH - Electrocardiography -MH - Heart Ventricles/*anatomy & histology -MH - Humans -MH - Magnetic Resonance Angiography -MH - Myocardium/ultrastructure -MH - Oxygen Consumption/physiology -MH - Pulmonary Circulation/physiology -MH - Stroke Volume/physiology -MH - Systole/physiology -MH - Ventricular Function, Left/physiology -MH - Ventricular Function, Right/*physiology -MH - Ventricular Septum/anatomy & histology -EDAT- 2012/05/03 06:00 -MHDA- 2012/07/17 06:00 -CRDT- 2012/05/03 06:00 -PHST- 2012/05/03 06:00 [entrez] -PHST- 2012/05/03 06:00 [pubmed] -PHST- 2012/07/17 06:00 [medline] -AID - S0733-8651(12)00028-8 [pii] -AID - 10.1016/j.ccl.2012.03.009 [doi] -PST - ppublish -SO - Cardiol Clin. 2012 May;30(2):167-87. doi: 10.1016/j.ccl.2012.03.009. - -PMID- 19211569 -OWN - NLM -STAT- MEDLINE -DCOM- 20090831 -LR - 20161125 -IS - 1532-2114 (Electronic) -IS - 1532-2114 (Linking) -VI - 10 -IP - 3 -DP - 2009 May -TI - Real-time three-dimensional transoesophageal echocardiography for guidance of - non-coronary interventions in the catheter laboratory. -PG - 341-9 -LID - 10.1093/ejechocard/jep006 [doi] -AB - The growing need for less invasive therapies of cardiac disease creates the - necessity for improved imaging guidance. Although two-dimensional transthoracic - and transoesophageal echocardiography (TEE) have been shown to be essential tools - for planning and execution of cardiac interventions, the benefit of - three-dimensional TEE for the guidance of interventional procedures still needs - to be evaluated. This review aims to describe our first experiences with - real-time (RT) three-dimensional TEE for the guidance of percutaneous - non-coronary interventions in the catheter laboratory. We used a matrix array TEE - probe capable of generating three-dimensional images of cardiac structures in RT. - We applied this innovative technique to monitor atrial septal defects or patent - foramen ovale closures, valve procedures such as mitral and aortic valve - interventions, and electrophysiological procedures. Our first experience using RT - three-dimensional TEE for the guidance of percutaneous cardiac interventions in - the catheter laboratory demonstrates that this technique is feasible to guide - interventions, providing fast and complete information about the underlying - pathomorphology, improving spatial orientation, and additionally allowing the - online monitoring of the procedure. These benefits may accelerate the learning - curve and improve confidence of the interventional cardiologist in order to - increase safety, accuracy, and efficacy of interventional cardiac procedures. -FAU - Balzer, Jan -AU - Balzer J -AD - Department of Cardiology, Pulmonology, and Vascular Medicine, University Hospital - RWTH Aachen, Germany. -FAU - Kelm, Malte -AU - Kelm M -FAU - Kühl, Harald P -AU - Kühl HP -LA - eng -PT - Journal Article -PT - Review -DEP - 20090210 -PL - England -TA - Eur J Echocardiogr -JT - European journal of echocardiography : the journal of the Working Group on - Echocardiography of the European Society of Cardiology -JID - 100890618 -SB - IM -MH - Aortic Valve Stenosis/diagnostic imaging/surgery -MH - Cardiac Surgical Procedures/*methods -MH - Echocardiography, Three-Dimensional/*methods -MH - Echocardiography, Transesophageal/*methods -MH - Heart Septal Defects, Atrial/diagnostic imaging/surgery -MH - Humans -MH - Mitral Valve Insufficiency/diagnostic imaging/surgery -MH - Time Factors -MH - Ultrasonography, Interventional/*methods -RF - 30 -EDAT- 2009/02/13 09:00 -MHDA- 2009/09/01 06:00 -CRDT- 2009/02/13 09:00 -PHST- 2009/02/13 09:00 [entrez] -PHST- 2009/02/13 09:00 [pubmed] -PHST- 2009/09/01 06:00 [medline] -AID - jep006 [pii] -AID - 10.1093/ejechocard/jep006 [doi] -PST - ppublish -SO - Eur J Echocardiogr. 2009 May;10(3):341-9. doi: 10.1093/ejechocard/jep006. Epub - 2009 Feb 10. - -PMID- 22322947 -OWN - NLM -STAT- MEDLINE -DCOM- 20120913 -LR - 20211021 -IS - 1559-0100 (Electronic) -IS - 1355-008X (Linking) -VI - 41 -IP - 3 -DP - 2012 Jun -TI - A new insight of mechanisms, diagnosis and treatment of diabetic cardiomyopathy. -PG - 398-409 -LID - 10.1007/s12020-012-9623-1 [doi] -AB - Diabetes mellitus is one of the most common chronic diseases across the world. - Cardiovascular complication is the major morbidity and mortality among the - diabetic patients. Diabetic cardiomyopathy, a new entity independent of coronary - artery disease or hypertension, has been increasingly recognized by clinicians - and epidemiologists. Cardiac dysfunction is the major characteristic of diabetic - cardiomyopathy. For a better understanding of diabetic cardiomyopathy and - necessary treatment strategy, several pathological mechanisms such as impaired - calcium handling and increased oxidative stress, have been proposed through - clinical and experimental observations. In this review, we will discuss the - development of cardiac dysfunction, the mechanisms underlying diabetic - cardiomyopathy, diagnostic methods, and treatment options. -FAU - Zhang, Xinli -AU - Zhang X -AD - School of Biomedical Sciences, University of Queensland, Room 409A, Sir William - MacGregor Building (64), St Lucia Campus, Brisbane, QLD 4072, Australia. -FAU - Chen, Chen -AU - Chen C -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120210 -PL - United States -TA - Endocrine -JT - Endocrine -JID - 9434444 -SB - IM -MH - Animals -MH - Diabetic Cardiomyopathies/*diagnosis/*physiopathology/therapy -MH - Heart/physiopathology -MH - Humans -EDAT- 2012/02/11 06:00 -MHDA- 2012/09/14 06:00 -CRDT- 2012/02/11 06:00 -PHST- 2011/12/07 00:00 [received] -PHST- 2012/01/28 00:00 [accepted] -PHST- 2012/02/11 06:00 [entrez] -PHST- 2012/02/11 06:00 [pubmed] -PHST- 2012/09/14 06:00 [medline] -AID - 10.1007/s12020-012-9623-1 [doi] -PST - ppublish -SO - Endocrine. 2012 Jun;41(3):398-409. doi: 10.1007/s12020-012-9623-1. Epub 2012 Feb - 10. - -PMID- 19712842 -OWN - NLM -STAT- MEDLINE -DCOM- 20100126 -LR - 20090828 -IS - 1879-0828 (Electronic) -IS - 0953-6205 (Linking) -VI - 20 -IP - 5 -DP - 2009 Sep -TI - Transient left ventricular ballooning syndrome. -PG - 454-6 -LID - 10.1016/j.ejim.2008.12.001 [doi] -AB - The transient left ventricular apical ballooning syndrome or takotsubo-like left - ventricular dysfunction refers to the ventricular morphological features present - in the heart of these patients. It resembles the Japanese Takotsubo, which means - a "fishing pot for trapping octopuses". This syndrome is characterized by - transient left ventricular dysfunction, electrocardiographic changes and minimal - release of myocardial enzymes that mimic acute anterior myocardial infarction, in - patients without angiographic coronary artery disease. Several pathophysiological - mechanisms have been proposed to explain it; however the precise aetiology - remains unknown. This condition is transient and has a good prognosis, however - Takotsubo cardiomyopathy as a new entity of acute heart failure, should be noted - and thought of as a cause of sudden cardiac death. Its proper diagnosis and - management greatly depends on our initial suspicion. -CI - 2008 European Federation of Internal Medicine. -FAU - Silva, Carla -AU - Silva C -AD - Department of Cardiology, Hospital S. João, Porto, Portugal. - carlasilva.md@gmail.com -FAU - Gonçalves, Alexandra -AU - Gonçalves A -FAU - Almeida, Rui -AU - Almeida R -FAU - Dias, Paula -AU - Dias P -FAU - Araújo, Vítor -AU - Araújo V -FAU - Gavina, Cristina -AU - Gavina C -FAU - Maciel, M Júlia -AU - Maciel MJ -LA - eng -PT - Journal Article -PT - Review -DEP - 20090130 -PL - Netherlands -TA - Eur J Intern Med -JT - European journal of internal medicine -JID - 9003220 -SB - IM -MH - Electrocardiography -MH - Humans -MH - Prognosis -MH - Risk Factors -MH - Takotsubo Cardiomyopathy/*diagnosis/etiology/*therapy -RF - 37 -EDAT- 2009/08/29 09:00 -MHDA- 2010/01/27 06:00 -CRDT- 2009/08/29 09:00 -PHST- 2008/02/28 00:00 [received] -PHST- 2008/10/29 00:00 [revised] -PHST- 2008/12/17 00:00 [accepted] -PHST- 2009/08/29 09:00 [entrez] -PHST- 2009/08/29 09:00 [pubmed] -PHST- 2010/01/27 06:00 [medline] -AID - S0953-6205(08)00333-6 [pii] -AID - 10.1016/j.ejim.2008.12.001 [doi] -PST - ppublish -SO - Eur J Intern Med. 2009 Sep;20(5):454-6. doi: 10.1016/j.ejim.2008.12.001. Epub - 2009 Jan 30. - -PMID- 21305480 -OWN - NLM -STAT- MEDLINE -DCOM- 20110607 -LR - 20110209 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 18 -IP - 1 -DP - 2011 -TI - Prognostic significance of QRS duration and morphology. -PG - 8-17 -AB - QRS duration and morphology, evaluated via a standard 12-lead electrocardiogram - (ECG), represent an opportunity to derive useful prognostic information regarding - the risk of subsequent cardiac events or therapeutic outcomes. Prolonged QRS - duration, and the presence of intraventricular conduction abnormalities, usually - indicate the presence of changes in the myocardium due to underlying heart - disease. Prolonged QRS duration is often associated with depressed ejection - fraction or enlarged left ventricular volumes, but several studies have - demonstrated that this simple ECG measure provides independent prognostic value, - after adjusting for relevant clinical covariates. Post-infarction patients with - prolonged QRS duration have a significantly increased risk of mortality, although - data associating QRS prolongation specifically with sudden death is less - supportive. In non-ischemic cardiomyopathy, there is no evidence that QRS - duration has prognostic significance in predicting mortality or sudden death. - Prolonged QRS duration, and especially presence of left bundle branch block, - seems to predict a benefit from cardiac resynchronization therapy in both - ischemic and non-ischemic cardiomyopathy patients. Therefore, QRS duration and - morphology should not only be considered a predictor of death or sudden death in - patients after myocardial infarction, and in those suspected of coronary artery - disease, but also as a predictor of benefit from cardiac resynchronization - therapy in patients with heart failure, whether of an ischemic or non-ischemic - origin. -FAU - Brenyo, Andrew -AU - Brenyo A -AD - Cardiology Division, Department of Medicine, University of Rochester Medical - Center, Rochester, NY, USA. -FAU - Zaręba, Wojciech -AU - Zaręba W -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -SB - IM -MH - *Electrocardiography -MH - Heart Conduction System/*physiopathology -MH - Heart Diseases/*diagnosis/mortality/physiopathology/therapy -MH - *Heart Rate -MH - Humans -MH - Predictive Value of Tests -MH - Prognosis -MH - Time Factors -EDAT- 2011/02/10 06:00 -MHDA- 2011/06/08 06:00 -CRDT- 2011/02/10 06:00 -PHST- 2011/02/10 06:00 [entrez] -PHST- 2011/02/10 06:00 [pubmed] -PHST- 2011/06/08 06:00 [medline] -PST - ppublish -SO - Cardiol J. 2011;18(1):8-17. - -PMID- 18431922 -OWN - NLM -STAT- MEDLINE -DCOM- 20080617 -LR - 20080424 -IS - 0033-2240 (Print) -IS - 0033-2240 (Linking) -VI - 64 Suppl 3 -DP - 2007 -TI - [Syncope in children]. -PG - 80-3 -AB - Syncope is a very common problem during childhood presenting to emergency - departments. It generates a great deal of anxiety among children and their - parents because of the fear that syncope are at risk for sudden death. - Neurocardiogenic (vaso-vagal) syncope are the most common, while cardiac type are - rare. The vaso-vagal syncope are secondary to irregularities in an autonomic - reflex resulting in an abnormal relaxation of the blood vessels. This is non-life - threatening form of syncope in differ cardiac type that can be very dangerous. In - cardiac syncope causes can be secondary to obstruction to blood flow (Tetralogy - of Fallot, cardiomyopathies, aortic stenosis), heart rhythm abnormalities (WPW, - L-QTS, A-V block) as well as ischemic heart disease secondary to an anomalous - coronary artery. The cardiac syncope are rare (6%) but the most inconvenient - because they can be life-threatening. -FAU - Szydłowski, Lesław -AU - Szydłowski L -AD - Katedra i Klinika Kardiologii Dzieciecej, Slaskiego Uniwersytetu Medycznego w - Katowicach. -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Omdlenia u dzieci. -PL - Poland -TA - Przegl Lek -JT - Przeglad lekarski -JID - 19840720R -SB - IM -MH - Arrhythmias, Cardiac/*complications -MH - Child -MH - Head-Down Tilt -MH - Humans -MH - Myocardial Ischemia/*complications -MH - Syncope/*diagnosis/*etiology -MH - Syncope, Vasovagal/diagnosis -RF - 24 -EDAT- 2008/04/25 09:00 -MHDA- 2008/06/18 09:00 -CRDT- 2008/04/25 09:00 -PHST- 2008/04/25 09:00 [pubmed] -PHST- 2008/06/18 09:00 [medline] -PHST- 2008/04/25 09:00 [entrez] -PST - ppublish -SO - Przegl Lek. 2007;64 Suppl 3:80-3. - -PMID- 17160372 -OWN - NLM -STAT- MEDLINE -DCOM- 20070223 -LR - 20181113 -IS - 0043-5341 (Print) -IS - 0043-5341 (Linking) -VI - 156 -IP - 21-22 -DP - 2006 Nov -TI - Aspects of the biology of hyaluronan, a largely neglected but extremely versatile - molecule. -PG - 563-8 -AB - HA takes part in a surprisingly large number of biological processes such as - embryogenesis, angiogenesis, cell motility, wound healing and cell adhesion. - While substantial progress in HA research has indeed been made over the last - years, many important questions have not yet been answered. One of the most - pertinent questions awaiting an answer is the quest for functional differences of - HA synthesized by the three HAS genes. Of similar importance would be - investigations into intracellular signaling pathways involved in the activation - of this gene family, a field in which to date very little is known. A better - understanding of functional differences between the HAS encoding genes not only - holds the promise for a better understanding of a series of biological processes - but also the opportunity for selective intervention in a number of maladies - characterized by abnormalities of HA levels. -FAU - Stuhlmeier, Karl M -AU - Stuhlmeier KM -AD - Ludwig Boltzmann Institute for Rheumatology and Balneology, Vienna, Austria. - karlms@excite.com -LA - eng -PT - Journal Article -PT - Review -PL - Austria -TA - Wien Med Wochenschr -JT - Wiener medizinische Wochenschrift (1946) -JID - 8708475 -RN - 0 (RNA, Messenger) -RN - 9004-61-9 (Hyaluronic Acid) -RN - EC 2.4.1.17 (Glucuronosyltransferase) -RN - EC 2.4.1.212 (HAS2 protein, human) -RN - EC 2.4.1.212 (Has2 protein, mouse) -RN - EC 2.4.1.212 (Hyaluronan Synthases) -SB - IM -MH - Animals -MH - Arthritis, Rheumatoid/drug therapy/enzymology/genetics/*metabolism -MH - Atherosclerosis/*metabolism -MH - Clinical Trials as Topic -MH - Coronary Restenosis/metabolism -MH - Disease Models, Animal -MH - Gene Regulatory Networks -MH - Glucuronosyltransferase/*genetics/metabolism -MH - Humans -MH - Hyaluronan Synthases -MH - Hyaluronic Acid/administration & - dosage/biosynthesis/blood/genetics/metabolism/*physiology -MH - Inflammation/metabolism -MH - Injections, Intra-Articular -MH - Mice -MH - Mice, Knockout -MH - Neoplasms/etiology/metabolism -MH - RNA, Messenger/metabolism -MH - Research -MH - Signal Transduction -RF - 57 -EDAT- 2006/12/13 09:00 -MHDA- 2007/02/24 09:00 -CRDT- 2006/12/13 09:00 -PHST- 2006/03/22 00:00 [received] -PHST- 2006/04/21 00:00 [accepted] -PHST- 2006/12/13 09:00 [pubmed] -PHST- 2007/02/24 09:00 [medline] -PHST- 2006/12/13 09:00 [entrez] -AID - 10.1007/s10354-006-0351-0 [doi] -PST - ppublish -SO - Wien Med Wochenschr. 2006 Nov;156(21-22):563-8. doi: 10.1007/s10354-006-0351-0. - -PMID- 21039751 -OWN - NLM -STAT- MEDLINE -DCOM- 20110504 -LR - 20110112 -IS - 1365-2990 (Electronic) -IS - 0305-1846 (Linking) -VI - 37 -IP - 1 -DP - 2011 Feb -TI - Review: role of cerebral vessels in ischaemic injury of the brain. -PG - 40-55 -LID - 10.1111/j.1365-2990.2010.01141.x [doi] -AB - This review discusses the pathological changes in the heart and vessels - underlying brain ischaemic injury, with a major focus on atherosclerotic disease - of the brain induced by lesions of the extracranial cervical and major - intracranial arteries and small-vessel disease of the brain. The carotid - bifurcation is the primary site for atherosclerotic changes, for which extensive - clinical trials and pathological analyses on carotid endarterectomy specimens - have been performed. Plaque rupture and erosion give rise to thrombus formation, - which leads to brain ischaemic injury. These changes have much in common with - atherosclerotic lesions of the subepicardial coronary arteries. Emboli of various - types of particles are characteristics of brain ischaemic injury. Thrombi rich in - fibrin and red blood cells (red thrombi) that develop in the cardiac chambers are - common sources of cerebral emboli. Small-vessel disease of the brain induces - fibrinoid necrosis, microaneurysm, fibrohyalinosis, lipohyalinosis and - microatheroma, changes commonly associated with hypertension. The acute - hypertensive small-vessel changes organize to create segmental arterial - disorganization and deep small infarcts when they escape from rupture. Some - specific vascular diseases responsible for brain ischaemic injury are briefly - reviewed also. -CI - © 2011 The Authors. Neuropathology and Applied Neurobiology © 2011 British - Neuropathological Society. -FAU - Ogata, J -AU - Ogata J -AD - Hirakata General Hospital for Developmental Disorders, Hirakata, Osaka 572-0122, - Japan. jogata@hirakataryoiku-med.or.jp -FAU - Yamanishi, H -AU - Yamanishi H -FAU - Ishibashi-Ueda, H -AU - Ishibashi-Ueda H -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Neuropathol Appl Neurobiol -JT - Neuropathology and applied neurobiology -JID - 7609829 -SB - IM -MH - Animals -MH - Atherosclerosis/pathology -MH - Blood Vessels/*pathology -MH - Brain/pathology -MH - Brain Ischemia/complications/*pathology -MH - Carotid Arteries/pathology -MH - Cerebral Arteries/pathology -MH - Cerebral Infarction/pathology -MH - Cerebrovascular Circulation/*physiology -MH - Heart Diseases/pathology -MH - Humans -MH - Intracranial Embolism/pathology -MH - Myocardium/pathology -MH - Necrosis -MH - Stroke/etiology/pathology -MH - Vertebral Artery/pathology -EDAT- 2010/11/03 06:00 -MHDA- 2011/05/05 06:00 -CRDT- 2010/11/03 06:00 -PHST- 2010/11/03 06:00 [entrez] -PHST- 2010/11/03 06:00 [pubmed] -PHST- 2011/05/05 06:00 [medline] -AID - 10.1111/j.1365-2990.2010.01141.x [doi] -PST - ppublish -SO - Neuropathol Appl Neurobiol. 2011 Feb;37(1):40-55. doi: - 10.1111/j.1365-2990.2010.01141.x. - -PMID- 19881337 -OWN - NLM -STAT- MEDLINE -DCOM- 20100219 -LR - 20101118 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 25 -IP - 1 -DP - 2010 Jan -TI - Fragmented QRS and other depolarization abnormalities as a predictor of mortality - and sudden cardiac death. -PG - 59-64 -LID - 10.1097/HCO.0b013e328333d35d [doi] -AB - PURPOSE OF REVIEW: Several invasive and noninvasive tests for risk stratification - of sudden cardiac death (SCD) have been studied. Tests such as microwave T wave - alternans (repolarization abnormality) and signal-averaged ECG (depolarization - abnormality) have high negative predictive values but low positive predictive - values in patients with heart disease. The presence of a fragmented QRS (fQRS) - complex on a routine 12-lead ECG is another marker of depolarization abnormality. - The purpose of this review is to discuss the potential utility of tests to detect - depolarization abnormalities of the heart for the risk stratification of - mortality and SCD with main emphasis on fQRS. RECENT FINDINGS: fQRS is associated - with increased mortality and arrhythmic events in patients with coronary artery - disease. fQRS has also been defined as a marker of arrhythmogenic right - ventricular cardiomyopathy and Brugada syndrome. In Brugada syndrome, the - presence of fQRS predicts episodes of ventricular fibrillation during follow-up. - SUMMARY: fQRS may be of value in determining the risk for SCD and guiding - selection for device therapy in patients with structural heart disease and - Brugada syndrome. It is possible that the predictive value of fQRS for SCD can be - enhanced further by combining a marker of repolarization abnormality such as - microwave T wave alternans. -FAU - Das, Mithilesh K -AU - Das MK -AD - Krannert Institute of Cardiology, Indiana University School of Medicine, - Indianapolis, Indiana 46202, USA. midas@iupui.edu -FAU - El Masry, Hicham -AU - El Masry H -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -SB - IM -MH - Arrhythmias, Cardiac/etiology -MH - Death, Sudden, Cardiac/*etiology -MH - Electrocardiography/*mortality -MH - Humans -MH - Magnetocardiography -MH - Predictive Value of Tests -MH - Risk Factors -RF - 33 -EDAT- 2009/11/03 06:00 -MHDA- 2010/02/20 06:00 -CRDT- 2009/11/03 06:00 -PHST- 2009/11/03 06:00 [entrez] -PHST- 2009/11/03 06:00 [pubmed] -PHST- 2010/02/20 06:00 [medline] -AID - 10.1097/HCO.0b013e328333d35d [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2010 Jan;25(1):59-64. doi: 10.1097/HCO.0b013e328333d35d. - -PMID- 23065345 -OWN - NLM -STAT- MEDLINE -DCOM- 20130131 -LR - 20211021 -IS - 1524-4571 (Electronic) -IS - 0009-7330 (Print) -IS - 0009-7330 (Linking) -VI - 111 -IP - 9 -DP - 2012 Oct 12 -TI - Mitochondria as a drug target in ischemic heart disease and cardiomyopathy. -PG - 1222-36 -LID - 10.1161/CIRCRESAHA.112.265660 [doi] -AB - Ischemic heart disease is a significant cause of morbidity and mortality in - Western society. Although interventions, such as thrombolysis and percutaneous - coronary intervention, have proven efficacious in ischemia and reperfusion - injury, the underlying pathological process of ischemic heart disease, laboratory - studies suggest further protection is possible, and an expansive research effort - is aimed at bringing new therapeutic options to the clinic. Mitochondrial - dysfunction plays a key role in the pathogenesis of ischemia and reperfusion - injury and cardiomyopathy. However, despite promising mitochondria-targeted drugs - emerging from the laboratory, very few have successfully completed clinical - trials. As such, the mitochondrion is a potential untapped target for new - ischemic heart disease and cardiomyopathy therapies. Notably, there are a number - of overlapping therapies for both these diseases, and as such novel therapeutic - options for one condition may find use in the other. This review summarizes - efforts to date in targeting mitochondria for ischemic heart disease and - cardiomyopathy therapy and outlines emerging drug targets in this field. -FAU - Walters, Andrew M -AU - Walters AM -AD - School of Medicine and Dentistry, University of Rochester Medical Center, - Rochester, NY 14642, USA. -FAU - Porter, George A Jr -AU - Porter GA Jr -FAU - Brookes, Paul S -AU - Brookes PS -LA - eng -GR - R01 HL071158/HL/NHLBI NIH HHS/United States -GR - TL1 RR024135/RR/NCRR NIH HHS/United States -GR - GM-087483/GM/NIGMS NIH HHS/United States -GR - 5 TL1 RR 24135-5/RR/NCRR NIH HHS/United States -GR - R01 GM087483/GM/NIGMS NIH HHS/United States -GR - HL-071158/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Circ Res -JT - Circulation research -JID - 0047103 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Animals -MH - Cardiomyopathies/drug therapy/*physiopathology -MH - Cardiovascular Agents/*pharmacology/therapeutic use -MH - Disease Models, Animal -MH - Humans -MH - Mitochondria, Heart/*drug effects/physiology -MH - Myocardial Ischemia/drug therapy/*physiopathology -MH - Treatment Outcome -PMC - PMC3507431 -MID - NIHMS414681 -EDAT- 2012/10/16 06:00 -MHDA- 2013/02/01 06:00 -PMCR- 2013/10/12 -CRDT- 2012/10/16 06:00 -PHST- 2012/10/16 06:00 [entrez] -PHST- 2012/10/16 06:00 [pubmed] -PHST- 2013/02/01 06:00 [medline] -PHST- 2013/10/12 00:00 [pmc-release] -AID - 111/9/1222 [pii] -AID - 10.1161/CIRCRESAHA.112.265660 [doi] -PST - ppublish -SO - Circ Res. 2012 Oct 12;111(9):1222-36. doi: 10.1161/CIRCRESAHA.112.265660. - -PMID- 19199921 -OWN - NLM -STAT- MEDLINE -DCOM- 20090330 -LR - 20220409 -IS - 0929-8673 (Print) -IS - 0929-8673 (Linking) -VI - 16 -IP - 5 -DP - 2009 -TI - Human urotensin II promotes hypertension and atherosclerotic cardiovascular - diseases. -PG - 550-63 -AB - Human urotensin II (U-II), the most potent vasoconstrictor undecapeptide - identified to date, and its receptor (UT) are involved in the pathogenesis of - systemic and pulmonary hypertension. Here, we review recent advances in our - understanding of the pathophysiology of U-II with particular reference to its - role in atherosclerotic cardiovascular diseases. Single-nucleotide polymorphisms - of U-II gene (S89N) are associated with onset of essential hypertension, type II - diabetes mellitus, and insulin resistance in the Asian population. Plasma U-II - levels are elevated in patients with vascular endothelial dysfunction-related - diseases such as essential hypertension, diabetes mellitus, atherosclerosis, - ischemic heart disease, and heart failure. Chronic infusion of U-II enhances - atherosclerotic lesions in the aorta in apolipoprotein E-knockout mice. In human - atherosclerotic plaques from the aorta and coronary and carotid arteries, U-II is - expressed at high levels in endothelial cells (ECs) and lymphocytes, whereas UT - is expressed at high levels in vascular smooth muscle cells (VSMCs), ECs, - monocytes, and macrophages. U-II stimulates vascular cell adhesion molecule-1 and - intercellular adhesion molecule-1 expression in human ECs as chemoattractant for - monocytes, and accelerates foam cell formation by up-regulation of acyl-coenzyme - A:cholesterol acyltransferase-1 in human monocyte-derived macrophages. U-II - produces reactive oxygen species (ROS) via nicotinamide adenine dinucleotide - phosphate oxidase activation in human VSMCs, and stimulates VSMC proliferation - with synergistic effects when combined with ROS, oxidized LDL, and serotonin. - Clinical studies demonstrated increased plasma U-II levels in accordance with the - severity of carotid atherosclerosis in patients with essential hypertension and - that of coronary artery lesions in patients with ischemic heart disease. Here, we - summarize the key roles of U-II in progression of hypertension and - atherosclerotic cardiovascular diseases. -FAU - Watanabe, Takuya -AU - Watanabe T -AD - Department of Biochemistry, Showa University School of Medicine, 1-5-8 Hatanodai, - Shinagawa-ku, Tokyo 142-8555, Japan. watanabemd@med.showa-u.ac.jp -FAU - Arita, Shigeko -AU - Arita S -FAU - Shiraishi, Yuji -AU - Shiraishi Y -FAU - Suguro, Toshiaki -AU - Suguro T -FAU - Sakai, Tetsuo -AU - Sakai T -FAU - Hongo, Shigeki -AU - Hongo S -FAU - Miyazaki, Akira -AU - Miyazaki A -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Urotensins) -RN - 9047-55-6 (urotensin II) -SB - IM -MH - Amino Acid Sequence -MH - Atherosclerosis/*physiopathology -MH - Humans -MH - Hypertension/*physiopathology -MH - Metabolic Syndrome/physiopathology -MH - Molecular Sequence Data -MH - Urotensins/*chemistry -MH - Vasoconstriction/physiology -RF - 139 -EDAT- 2009/02/10 09:00 -MHDA- 2009/03/31 09:00 -CRDT- 2009/02/10 09:00 -PHST- 2009/02/10 09:00 [entrez] -PHST- 2009/02/10 09:00 [pubmed] -PHST- 2009/03/31 09:00 [medline] -AID - 10.2174/092986709787458515 [doi] -PST - ppublish -SO - Curr Med Chem. 2009;16(5):550-63. doi: 10.2174/092986709787458515. - -PMID- 19365285 -OWN - NLM -STAT- MEDLINE -DCOM- 20090915 -LR - 20250623 -IS - 1473-5598 (Electronic) -IS - 0263-6352 (Linking) -VI - 27 -IP - 7 -DP - 2009 Jul -TI - The prevalence of atherosclerotic renal artery stenosis in risk groups: a - systematic literature review. -PG - 1333-40 -LID - 10.1097/HJH.0b013e328329bbf4 [doi] -AB - OBJECTIVE: We performed a literature review and analysis to improve the insight - in the prevalence of renal artery stenosis (RAS) in risk groups. METHODS: - Relevant studies were identified by a MEDLINE and EMBASE database search (1966 to - December 2007), complemented by hand searching of reference lists. Review was - restricted to English language studies, using any form of angiography as - diagnostic method. Studies were grouped in risk group categories sharing similar - clinical characteristics, and pooled prevalence rates were calculated for each - category. RESULTS: Forty studies, involving a total number of 15 879 patients, - were identified. The following pooled prevalence rates (95% confidence interval; - sample size risk group) of RAS were found: suspected renovascular hypertension, - 14.1% (12.7-15.8%; n = 1931); hypertension and diabetes mellitus, 20% - (14.9-25.1%; n = 240); coronary angiography (CAG) in consecutive patients, 10.5% - (9.8-11.2%; n = 8011); CAG in hypertensive patients, 17.8% (15.4-20.6%; n = 836); - CAG and suspected renovascular disease, 16.6% (14.8-18.5%; n = 1576); congestive - heart failure, 54.1% (45.7-62.3%; n = 135); peripheral vascular disease, 25.3% - (23.6-27.0%; n = 2632); abdominal aortic aneurysm, 33.1% (27.4-39.2%; n = 239) - and end-stage renal failure, 40.8% (27-55.8%; n = 49.) In patients with an - incidentally discovered RAS, hypertension and renal failure were present in 65.5 - and 27.5%, respectively. CONCLUSION: RAS has a high prevalence in risk groups, - especially in those with extrarenal atherosclerosis, end-stage renal failure and - heart failure. These findings are important when screening for RAS or - prescription of an angiotensin converting enzyme inhibitor or angiotensin-II - receptor blocker is considered. -FAU - de Mast, Quirijn -AU - de Mast Q -AD - Department of General Internal Medicine, Radboud University Nijmegen Medical - Center, Nijmegen, The Netherlands. q.demast@aig.umcn.nl -FAU - Beutler, Jaap J -AU - Beutler JJ -LA - eng -PT - Journal Article -PT - Systematic Review -PL - Netherlands -TA - J Hypertens -JT - Journal of hypertension -JID - 8306882 -SB - IM -MH - Atherosclerosis/*epidemiology -MH - Coronary Angiography -MH - Humans -MH - Prevalence -MH - Renal Artery Obstruction/*epidemiology -MH - Risk Factors -RF - 70 -EDAT- 2009/04/15 09:00 -MHDA- 2009/09/16 06:00 -CRDT- 2009/04/15 09:00 -PHST- 2009/04/15 09:00 [entrez] -PHST- 2009/04/15 09:00 [pubmed] -PHST- 2009/09/16 06:00 [medline] -AID - 10.1097/HJH.0b013e328329bbf4 [doi] -PST - ppublish -SO - J Hypertens. 2009 Jul;27(7):1333-40. doi: 10.1097/HJH.0b013e328329bbf4. - -PMID- 22875822 -OWN - NLM -STAT- MEDLINE -DCOM- 20130729 -LR - 20220330 -IS - 1468-201X (Electronic) -IS - 1355-6037 (Linking) -VI - 98 -IP - 17 -DP - 2012 Sep -TI - Remote ischaemic preconditioning in coronary artery bypass surgery: a - meta-analysis. -PG - 1267-71 -LID - 10.1136/heartjnl-2011-301551 [doi] -AB - AIM: Randomised trials exploring remote ischaemic preconditioning (RIPC) in - patients undergoing coronary artery bypass graft (CABG) surgery have yielded - conflicting data regarding potential cardiovascular and renal protection, and are - individually flawed by small sample size. METHODS: Three investigators - independently searched the MEDLINE, EMBASE and Cochrane databases to identify - randomised trials testing RIPC in patients undergoing CABG. RESULTS: Nine studies - with 704 patients were included. Standardised mean difference of troponin I and T - release showed a significant decrease (-0.36 (95% CI -0.62 to -0.09)). This - difference held true after excluding the trials with cross-clamp fibrillation, - the study with off-pump CABG and studies using a flurane as anaesthetic agent - (-0.41 (95% CI -0.69 to -0.12), -0.38 (95% CI -0.70 to -0.07) and -0.37 (95% CI - -0.63 to -0.12), respectively). A similar trend was also obtained for patients - with multivessel disease (-0.41 (95% CI -0.73 to -0.08)). The trials evaluating - postoperative creatinine reported a non-significant reduction (0.02 (95% CI -0.09 - to 0.13)). Moreover, the length of in-hospital stay was not influenced by the - kind of treatment (weighted mean difference 0.27 (95% CI -0.24 to 0.79)). - CONCLUSION: RIPC reduced the release of troponin in patients undergoing CABG. - Larger randomised trials are needed to clarify the presence of a causal - relationship between RIPC-induced troponin release and clinical adverse events. -FAU - D'Ascenzo, Fabrizio -AU - D'Ascenzo F -AD - Division of Cardiology, University of Turin, Turin, Italy. -FAU - Cavallero, Erika -AU - Cavallero E -FAU - Moretti, Claudio -AU - Moretti C -FAU - Omedè, Pierluigi -AU - Omedè P -FAU - Sciuto, Filippo -AU - Sciuto F -FAU - Rahman, Ishtiaq A -AU - Rahman IA -FAU - Bonser, Robert S -AU - Bonser RS -FAU - Yunseok, Jeon -AU - Yunseok J -FAU - Wagner, Robert -AU - Wagner R -FAU - Freiberger, Tomas -AU - Freiberger T -FAU - Kunst, Gudrun -AU - Kunst G -FAU - Marber, Michael S -AU - Marber MS -FAU - Thielmann, Matthias -AU - Thielmann M -FAU - Ji, Bingyang -AU - Ji B -FAU - Amr, Yasser M -AU - Amr YM -FAU - Modena, Maria Grazia -AU - Modena MG -FAU - Zoccai, Giuseppe Biondi -AU - Zoccai GB -FAU - Sheiban, Imad -AU - Sheiban I -FAU - Gaita, Fiorenzo -AU - Gaita F -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PL - England -TA - Heart -JT - Heart (British Cardiac Society) -JID - 9602087 -RN - 0 (Biomarkers) -RN - 0 (Troponin I) -RN - 0 (Troponin T) -RN - AYI8EX34EU (Creatinine) -SB - IM -MH - Biomarkers/blood -MH - Coronary Artery Bypass/*methods -MH - Creatinine/analysis -MH - Humans -MH - *Ischemic Preconditioning, Myocardial -MH - Length of Stay -MH - Myocardial Reperfusion Injury/prevention & control -MH - Randomized Controlled Trials as Topic -MH - Troponin I/blood -MH - Troponin T/blood -EDAT- 2012/08/10 06:00 -MHDA- 2013/07/31 06:00 -CRDT- 2012/08/10 06:00 -PHST- 2012/08/10 06:00 [entrez] -PHST- 2012/08/10 06:00 [pubmed] -PHST- 2013/07/31 06:00 [medline] -AID - heartjnl-2011-301551 [pii] -AID - 10.1136/heartjnl-2011-301551 [doi] -PST - ppublish -SO - Heart. 2012 Sep;98(17):1267-71. doi: 10.1136/heartjnl-2011-301551. - -PMID- 16487830 -OWN - NLM -STAT- MEDLINE -DCOM- 20060428 -LR - 20220331 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 47 -IP - 4 -DP - 2006 Feb 21 -TI - The pathogenesis of myocardial fibrosis in the setting of diabetic - cardiomyopathy. -PG - 693-700 -AB - Diabetes has emerged as a major threat to worldwide health. The increasing - incidence of diabetes in young individuals is particularly worrisome given that - the disease is likely to evolve over a period of years. In 1972, the existence of - a diabetic cardiomyopathy was proposed based on the experience with four adult - diabetic patients who suffered from congestive heart failure in the absence of - discernible coronary artery disease, valvular or congenital heart disease, - hypertension, or alcoholism. The exact mechanisms underlying the disease are - unknown; however, an important component of the pathological alterations observed - in these hearts includes the accumulation of extracellular matrix (ECM) proteins, - in particular collagens. The excess deposition of ECM in the heart mirrors what - occurs in other organs such as the kidney and peritoneum of diabetics. Mechanisms - responsible for these alterations may include the excess production, reduced - degradation, and/or chemical modification of ECM proteins. These effects may be - the result of direct or indirect actions of high glucose concentrations. This - article reviews our state of knowledge on the effects that diabetes-like - conditions exert on the cells responsible for ECM production as well as relevant - experimental and clinical data. -FAU - Asbun, Juan -AU - Asbun J -AD - Escuela Superior de Medicina del Instituto Politécnico Nacional, Mexico City, - Mexico. -FAU - Villarreal, Francisco J -AU - Villarreal FJ -LA - eng -PT - Journal Article -PT - Review -DEP - 20060126 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Reactive Oxygen Species) -SB - IM -MH - Animals -MH - Cardiomyopathies/pathology/*physiopathology -MH - *Diabetes Complications -MH - Diabetes Mellitus, Experimental/pathology/physiopathology -MH - Fibrosis -MH - Humans -MH - Hyperglycemia/complications/physiopathology -MH - Myocardium/pathology -MH - Paracrine Communication -MH - Reactive Oxygen Species/metabolism -MH - Signal Transduction -MH - Stress, Mechanical -RF - 89 -EDAT- 2006/02/21 09:00 -MHDA- 2006/04/29 09:00 -CRDT- 2006/02/21 09:00 -PHST- 2005/05/19 00:00 [received] -PHST- 2005/08/24 00:00 [revised] -PHST- 2005/09/26 00:00 [accepted] -PHST- 2006/02/21 09:00 [pubmed] -PHST- 2006/04/29 09:00 [medline] -PHST- 2006/02/21 09:00 [entrez] -AID - S0735-1097(05)02747-6 [pii] -AID - 10.1016/j.jacc.2005.09.050 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2006 Feb 21;47(4):693-700. doi: 10.1016/j.jacc.2005.09.050. - Epub 2006 Jan 26. - -PMID- 17296457 -OWN - NLM -STAT- MEDLINE -DCOM- 20070313 -LR - 20151119 -IS - 0149-2918 (Print) -IS - 0149-2918 (Linking) -VI - 28 -IP - 12 -DP - 2006 Dec -TI - Ranolazine for the management of coronary artery disease. -PG - 1996-2007 -AB - BACKGROUND: Despite coronary revascularization and standard antianginal therapy, - many patients continue to experience symptoms of stable angina and progression of - their disease. Ranolazine is a new class of antianginal agent. Unlike standard - antianginal agents, it alters glucose and fatty acid metabolism for a different - approach to the management of coronary artery disease. OBJECTIVE: This article - discusses the clinical pharmacology of ranolazine and its use in the management - of chronic stable angina. METHODS: Peer-reviewed articles and abstracts were - identified from MEDLINE and the Current Contents database (both from 1966 to - September 20, 2006) using the search terms ranolazine, angina, pharmacokinetics, - and pharmacology. Citations from available articles were reviewed for additional - references. Abstracts presented at recent professional meetings were also - reviewed. RESULTS: Ranolazine is a cell membrane inhibitor of the late sodium - current. Extended-release ranolazine was recently approved in the United States - for the treatment of chronic angina. Ranolazine is metabolized in the liver by - the cytochrome P-450 (CYP) 3A4 system. Because of its potential to prolong - corrected QT (QTc) intervals, ranolazine should not be used in patients with - hepatic impairment, those with QTc prolongation, or those taking drugs known to - prolong QTc intervals or drugs that are potent CYP 3A4 inhibitors. Other adverse - effects of ranolazine include dizziness, headache, constipation, and nausea. - Placebo-controlled clinical studies performed to date have found that - sustained-release ranolazine 500 to 1500 mg PO BID was associated with - significantly increased time to onset of angina (range of increase, 27.0-144.0 s; - P < 0.05 [varied among studies]), exercise duration (range of increase, 23.8-99.0 - s; P < 0.05 [varied among studies] ), and time to 1-mm ST depression (range of - increase, 27.6-146.2 s; P < 0.05 [varied among studies]). In addition, exercise - duration was found to be significantly longer with ranolazine compared with - atenolol (453 vs 430 s; P = 0.006). CONCLUSIONS: Ranolazine is a new antianginal - agent that is effective in the management of chronic angina. Its unique mechanism - of action warrants further study in other cardiovascular conditions such as heart - failure and arrhythmias. Ongoing studies will address whether ranolazine can - reduce clinical end points such as cardiovascular death and myocardial - infarction. -FAU - Cheng, Judy W M -AU - Cheng JW -AD - Department of Pharmacy Practice, Long Island University, Brooklyn, New York, USA. - judy.cheng@liu.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Ther -JT - Clinical therapeutics -JID - 7706726 -RN - 0 (Acetanilides) -RN - 0 (Enzyme Inhibitors) -RN - 0 (Piperazines) -RN - A6IEZ5M406 (Ranolazine) -SB - IM -MH - Acetanilides/adverse effects/pharmacokinetics/*therapeutic use -MH - Angina Pectoris/*drug therapy/etiology -MH - Clinical Trials as Topic -MH - Enzyme Inhibitors/adverse effects/pharmacokinetics/*therapeutic use -MH - Humans -MH - Piperazines/adverse effects/pharmacokinetics/*therapeutic use -MH - Ranolazine -MH - Treatment Outcome -RF - 28 -EDAT- 2007/02/14 09:00 -MHDA- 2007/03/14 09:00 -CRDT- 2007/02/14 09:00 -PHST- 2006/10/03 00:00 [accepted] -PHST- 2007/02/14 09:00 [pubmed] -PHST- 2007/03/14 09:00 [medline] -PHST- 2007/02/14 09:00 [entrez] -AID - S0149-2918(06)00312-2 [pii] -AID - 10.1016/j.clinthera.2006.12.009 [doi] -PST - ppublish -SO - Clin Ther. 2006 Dec;28(12):1996-2007. doi: 10.1016/j.clinthera.2006.12.009. - -PMID- 18313627 -OWN - NLM -STAT- MEDLINE -DCOM- 20080325 -LR - 20080303 -IS - 1551-7136 (Print) -IS - 1551-7136 (Linking) -VI - 4 -IP - 1 -DP - 2008 Jan -TI - Heart failure with preserved ejection fraction: hypertension, diabetes, - obesity/sleep apnea, and hypertrophic and infiltrative cardiomyopathy. -PG - 87-97 -LID - 10.1016/j.hfc.2007.11.001 [doi] -AB - The detailed pathophysiology of heart failure with preserved ejection fraction - (HF-PEF) remains an area of active research and controversy; however, - abnormalities of diastolic function are generally believed to play an important - role. Most commonly, diastolic dysfunction occurs as a consequence of myocyte - hypertrophy, endomyocardial fibrosis, and abnormalities of intracellular calcium - handling that are related to normal myocardial aging and accelerated by - comorbidities such as hypertension, diabetes, coronary artery disease, and - obesity. In this article, three fundamental risk factors are considered for - "secondary" diastolic dysfunction and HF-hypertension, diabetes, and obesity-with - an emphasis on the clinical epidemiology, pathophysiologic mechanisms, and - treatment implications of each. The article concludes with a brief discussion of - "primary" diastolic HF due to infiltrative or restrictive cardiomyopathies. -FAU - Desai, Akshay -AU - Desai A -AD - Brigham and Women's Hospital, Boston, MA 02115, USA. adesai@partners.org -FAU - Fang, James C -AU - Fang JC -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Clin -JT - Heart failure clinics -JID - 101231934 -SB - IM -MH - Amyloidosis -MH - Cardiomyopathy, Hypertrophic/drug therapy/*physiopathology -MH - Diabetes Mellitus/*physiopathology -MH - Heart Failure/drug therapy/*physiopathology -MH - Humans -MH - Hypertension/drug therapy/*physiopathology -MH - Obesity/*physiopathology -MH - Sleep Apnea Syndromes/*physiopathology -RF - 105 -EDAT- 2008/03/04 09:00 -MHDA- 2008/03/26 09:00 -CRDT- 2008/03/04 09:00 -PHST- 2008/03/04 09:00 [pubmed] -PHST- 2008/03/26 09:00 [medline] -PHST- 2008/03/04 09:00 [entrez] -AID - S1551-7136(07)00141-9 [pii] -AID - 10.1016/j.hfc.2007.11.001 [doi] -PST - ppublish -SO - Heart Fail Clin. 2008 Jan;4(1):87-97. doi: 10.1016/j.hfc.2007.11.001. - -PMID- 21143003 -OWN - NLM -STAT- MEDLINE -DCOM- 20110323 -LR - 20181201 -IS - 1744-7658 (Electronic) -IS - 1354-3784 (Linking) -VI - 20 -IP - 1 -DP - 2011 Jan -TI - Prasugrel for the treatment of coronary thrombosis: a review of pharmacological - properties, indications for use and future development. -PG - 119-33 -LID - 10.1517/13543784.2010.538381 [doi] -AB - IMPORTANCE OF THE FIELD: Dual antiplatelet therapy with aspirin and the P2Y(12) - receptor antagonist clopidogrel is the cornerstone of treatment for prevention of - recurrent ischemic events in high-risk patients. Despite the benefits of this - strategy, a number of patients experience recurrent atherothrombotic events. - Investigations have shown that this may be in part related to the broad range in - pharmacodynamic response to clopidogrel, which includes patients with poor - platelet inhibitory effects who have an increased risk of events. AREAS COVERED - IN THIS REVIEW: Prasugrel (CS-747; LY-640315) is a novel, third-generation oral - thienopyridine that is a specific, irreversible antagonist of the platelet - P2Y(12) receptor. Laboratory results with prasugrel support more potent - antiplatelet effects, a lower incidence of interpatient variability in - antiplatelet response, and a reduced time to onset of antiplatelet activity - compared with clopidogrel. WHAT THE READER WILL GAIN: This manuscript reviews the - pharmacological properties, safety and efficacy of prasugrel and provides current - indications for its use and future development. TAKE HOME MESSAGE: Prasugrel - exerts more prompt, potent and predictable antiplatelet effects than clopidogrel. - These translate into a greater reduction in ischemic events, including stent - thrombosis, in acute coronary syndrome patients undergoing percutaneous coronary - intervention albeit at the expense of an increased risk of bleeding. -FAU - Tomasello, Salvatore D -AU - Tomasello SD -AD - University of Florida College of Medicine-Jacksonville, 655 West 8th Street, - Jacksonville, Florida 32209, USA. dominick.angiolillo@jax.ufl.edu -FAU - Tello-Montoliu, Antonio -AU - Tello-Montoliu A -FAU - Angiolillo, Dominick J -AU - Angiolillo DJ -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -DEP - 20101213 -PL - England -TA - Expert Opin Investig Drugs -JT - Expert opinion on investigational drugs -JID - 9434197 -RN - 0 (Piperazines) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Purinergic P2Y Receptor Antagonists) -RN - 0 (Thiophenes) -RN - A74586SNO7 (Clopidogrel) -RN - G89JQ59I13 (Prasugrel Hydrochloride) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Animals -MH - Clopidogrel -MH - Coronary Thrombosis/*drug therapy/physiopathology -MH - Humans -MH - Piperazines/adverse effects/pharmacology/*therapeutic use -MH - Platelet Aggregation Inhibitors/adverse effects/pharmacology/therapeutic use -MH - Prasugrel Hydrochloride -MH - Purinergic P2Y Receptor Antagonists/adverse effects/pharmacology/*therapeutic use -MH - Thiophenes/adverse effects/pharmacology/*therapeutic use -MH - Ticlopidine/adverse effects/analogs & derivatives/pharmacology/therapeutic use -EDAT- 2010/12/15 06:00 -MHDA- 2011/03/24 06:00 -CRDT- 2010/12/15 06:00 -PHST- 2010/12/15 06:00 [entrez] -PHST- 2010/12/15 06:00 [pubmed] -PHST- 2011/03/24 06:00 [medline] -AID - 10.1517/13543784.2010.538381 [doi] -PST - ppublish -SO - Expert Opin Investig Drugs. 2011 Jan;20(1):119-33. doi: - 10.1517/13543784.2010.538381. Epub 2010 Dec 13. - -PMID- 21192242 -OWN - NLM -STAT- MEDLINE -DCOM- 20130617 -LR - 20131121 -IS - 1536-3686 (Electronic) -IS - 1075-2765 (Linking) -VI - 20 -IP - 1 -DP - 2013 Jan -TI - Statin-associated rhabdomyolysis with acute renal failure complicated by - intradialytic NSTEMI: a review of lipid management considerations. -PG - 57-60 -LID - 10.1097/MJT.0b013e3181ff7c79 [doi] -AB - Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are - associated with myopathy, myalgias, myositis, and rhabdomyolysis. Rhabdoymyolysis - is a rare complication and may cause acute renal failure, which may be fatal. In - such cases, alternative therapies should be considered. In this review, we - attempted to elucidate the lipid management options in patients with - rhabdomyolysis and coronary artery disease. We also describe a case report of a - patient who developed rhabdomyolysis from dual antilipid therapy followed by - acute renal failure and non-ST elevation myocardial infarction. Such a complex - case has not been reported in the literature, and lipid management options may - include niacin, omega 3-fatty acids, or bile acid sequestrants. Once alternative - therapies are initiated, monitoring a patient closely with evaluation for - associated adverse events should be performed. -FAU - Kar, Subrata -AU - Kar S -AD - Department of Cardiology, Harry S Truman Memorial Veterans' Hospital, Columbia, - MO, USA. -FAU - Chockalingam, Anand -AU - Chockalingam A -LA - eng -PT - Case Reports -PT - Journal Article -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - United States -TA - Am J Ther -JT - American journal of therapeutics -JID - 9441347 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Hypolipidemic Agents) -RN - AGG2FN16EV (Simvastatin) -RN - Q8X02027X3 (Gemfibrozil) -SB - IM -MH - Acute Kidney Injury/diagnosis/*etiology/therapy -MH - Aged, 80 and over -MH - Coronary Artery Disease/*drug therapy -MH - Drug Therapy, Combination -MH - Gemfibrozil/adverse effects/therapeutic use -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*adverse effects/therapeutic use -MH - Hypolipidemic Agents/adverse effects/therapeutic use -MH - Male -MH - Myocardial Infarction/diagnosis/*etiology -MH - Renal Dialysis/*adverse effects -MH - Rhabdomyolysis/*chemically induced/complications/diagnosis -MH - Simvastatin/*adverse effects/therapeutic use -EDAT- 2010/12/31 06:00 -MHDA- 2013/06/19 06:00 -CRDT- 2010/12/31 06:00 -PHST- 2010/12/31 06:00 [entrez] -PHST- 2010/12/31 06:00 [pubmed] -PHST- 2013/06/19 06:00 [medline] -AID - 10.1097/MJT.0b013e3181ff7c79 [doi] -PST - ppublish -SO - Am J Ther. 2013 Jan;20(1):57-60. doi: 10.1097/MJT.0b013e3181ff7c79. - -PMID- 22871192 -OWN - NLM -STAT- MEDLINE -DCOM- 20121218 -LR - 20151119 -IS - 1744-8298 (Electronic) -IS - 1479-6678 (Linking) -VI - 8 -IP - 4 -DP - 2012 Jul -TI - Rivaroxaban for stroke prevention in atrial fibrillation and secondary prevention - in patients with a recent acute coronary syndrome. -PG - 533-41 -LID - 10.2217/fca.12.26 [doi] -AB - The occurrence of disabling stroke, the major fatal consequence of atrial - fibrillation, can be reduced by almost two-thirds with warfarin oral - anticoagulation. Recent estimates on the prevalence of atrial fibrillation in the - USA suggest that approximately 3 million people suffer from this common cardiac - arrhythmia, therefore, the socioeconomic impact of adequate oral anticoagulation - is enormous. Rivaroxaban, a direct orally available factor Xa inhibitor, is the - first of a new class of drugs that target a central factor of the coagulation - cascade upstream of thrombin. In the ROCKET AF clinical trial, rivaroxaban - demonstrated noninferiority compared with warfarin for stroke prevention in - patients with atrial fibrillation, while intracranial and fatal bleeding occurred - less frequently with rivaroxaban treatment. Rivaroxban has recently been approved - for the prevention of stroke and systemic embolism in patients with nonvalvular - atrial fibrillation by the US FDA and EMA. Very recently, rivaroxaban in addition - to dual antiplatelet therapy, was shown to reduce mortality in patients with a - recent acute coronary syndrome in the ATLAS ACS 2-TIMI 51 clinical trial. The - clinical evaluation of rivaroxaban in cardiovascular disease and the results of - the ROCKET AF study, the landmark clinical trial of rivaroxaban for stroke - prevention, are discussed along with the unique pharmacological profile of - rivaroxaban. -FAU - Ahrens, Ingo -AU - Ahrens I -AD - Clinic for Cardiology & Angiology I, University Heart Centre Freiburg-Bad - Krozingen, Hugstetter Street 55, Freiburg, Germany. - ingo.ahrens@universitaets-herzzentrum.de -FAU - Bode, Christoph -AU - Bode C -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Future Cardiol -JT - Future cardiology -JID - 101239345 -RN - 0 (Anticoagulants) -RN - 0 (Factor Xa Inhibitors) -RN - 0 (Morpholines) -RN - 0 (Thiophenes) -RN - 5Q7ZVV76EI (Warfarin) -RN - 9NDF7JZ4M3 (Rivaroxaban) -SB - IM -MH - Acute Coronary Syndrome/mortality/*prevention & control -MH - Anticoagulants/adverse effects/*pharmacology/*therapeutic use -MH - Atrial Fibrillation/*complications -MH - Clinical Trials, Phase III as Topic -MH - Drug Approval -MH - *Factor Xa Inhibitors -MH - Humans -MH - Morpholines/adverse effects/*pharmacology/*therapeutic use -MH - Rivaroxaban -MH - *Secondary Prevention -MH - Stroke/*etiology -MH - Thiophenes/adverse effects/*pharmacology/*therapeutic use -MH - Warfarin/adverse effects/therapeutic use -EDAT- 2012/08/09 06:00 -MHDA- 2012/12/19 06:00 -CRDT- 2012/08/09 06:00 -PHST- 2012/08/09 06:00 [entrez] -PHST- 2012/08/09 06:00 [pubmed] -PHST- 2012/12/19 06:00 [medline] -AID - 10.2217/fca.12.26 [doi] -PST - ppublish -SO - Future Cardiol. 2012 Jul;8(4):533-41. doi: 10.2217/fca.12.26. - -PMID- 22726250 -OWN - NLM -STAT- MEDLINE -DCOM- 20130129 -LR - 20250626 -IS - 1471-2261 (Electronic) -IS - 1471-2261 (Linking) -VI - 12 -DP - 2012 Jun 24 -TI - Heart disease and left ventricular rotation - a systematic review and - quantitative summary. -PG - 46 -LID - 10.1186/1471-2261-12-46 [doi] -AB - BACKGROUND: Left ventricular (LV) rotation is increasingly examined in those with - heart disease. The available evidence measuring LV rotation in those with heart - diseases has not been systematically reviewed. METHODS: To review systematically - the evidence measuring LV rotational changes in various heart diseases compared - to healthy controls, literature searches were conducted for appropriate articles - using several electronic databases (e.g., MEDLINE, EMBASE). All - randomized-controlled trials, prospective cohort and case-controlled studies that - assessed LV rotation in relation to various heart conditions were included. Three - independent reviewers evaluated each investigation's quality using validated - scales. Results were tabulated and levels of evidence assigned. RESULTS: A total - of 1,782 studies were found through the systematic literature search. Upon review - of the articles, 47 were included. The articles were separated into those - investigating changes in LV rotation in participants with: aortic stenosis, - myocardial infarction, hypertrophic cardiomyopathy, dilated cardiomyopathy, - non-compaction, restrictive cardiomyopathy/ constrictive pericarditis, heart - failure, diastolic dysfunction, heart transplant, implanted pacemaker, coronary - artery disease and cardiovascular disease risk factors. Evidence showing changes - in LV rotation due to various types of heart disease was supported by evidence - with limited to moderate methodological quality. CONCLUSIONS: Despite a - relatively low quality and volume of evidence, the literature consistently shows - that heart disease leads to marked changes in LV rotation, while rotational - systolic-diastolic coupling is preserved. No prognostic information exists on the - potential value of rotational measures of LV function. The literature suggests - that measures of LV rotation may aid in diagnosing subclinical aortic stenosis - and diastolic dysfunction. -FAU - Phillips, Aaron A -AU - Phillips AA -AD - Faculty of Medicine, University of British Columbia, Vancouver, Canada. -FAU - Cote, Anita T -AU - Cote AT -FAU - Bredin, Shannon S D -AU - Bredin SS -FAU - Warburton, Darren E R -AU - Warburton DE -LA - eng -GR - Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20120624 -PL - England -TA - BMC Cardiovasc Disord -JT - BMC cardiovascular disorders -JID - 100968539 -SB - IM -MH - Biomechanical Phenomena -MH - Diastole -MH - Evidence-Based Medicine -MH - Heart Diseases/*diagnosis/physiopathology -MH - Humans -MH - Predictive Value of Tests -MH - Prognosis -MH - Rotation -MH - Systole -MH - Torsion Abnormality/*diagnosis/physiopathology -MH - Ventricular Dysfunction, Left/*diagnosis/physiopathology -MH - *Ventricular Function, Left -PMC - PMC3423007 -EDAT- 2012/06/26 06:00 -MHDA- 2013/01/30 06:00 -PMCR- 2012/06/24 -CRDT- 2012/06/26 06:00 -PHST- 2012/01/11 00:00 [received] -PHST- 2012/06/24 00:00 [accepted] -PHST- 2012/06/26 06:00 [entrez] -PHST- 2012/06/26 06:00 [pubmed] -PHST- 2013/01/30 06:00 [medline] -PHST- 2012/06/24 00:00 [pmc-release] -AID - 1471-2261-12-46 [pii] -AID - 10.1186/1471-2261-12-46 [doi] -PST - epublish -SO - BMC Cardiovasc Disord. 2012 Jun 24;12:46. doi: 10.1186/1471-2261-12-46. - -PMID- 23174552 -OWN - NLM -STAT- MEDLINE -DCOM- 20130524 -LR - 20220316 -IS - 1934-1563 (Electronic) -IS - 1934-1482 (Linking) -VI - 4 -IP - 11 -DP - 2012 Nov -TI - Exercise in cardiovascular diseases. -PG - 867-73 -LID - S1934-1482(12)01631-0 [pii] -LID - 10.1016/j.pmrj.2012.10.003 [doi] -AB - Analysis of extensive data has shown that exercise training provides significant - impact on prevention and modification of cardiovascular diseases and mortality. - In general, exercise recommendations for patients with cardiovascular diseases - are based on individual aerobic capacity and comorbidities. Patients with acute - syndromes benefit from participating in a cardiac rehabilitation program, whereas - patients with chronic syndromes benefit from a life-long home-based program. In - general, exercise prescription should involve aerobic activities in combination - with resistance, flexibility, and balance exercises. This review will discuss an - exercise prescription for patients with coronary artery disease, heart failure, - and after heart transplantation. Detailed precautions for particular groups of - patients will be discussed. -CI - Copyright © 2012 American Academy of Physical Medicine and Rehabilitation. - Published by Elsevier Inc. All rights reserved. -FAU - Perez-Terzic, Carmen M -AU - Perez-Terzic CM -AD - Cardiovascular Rehabilitation Program, Department of Physical Medicine and - Rehabilitation, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA. - terzic.carmen@mayo.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - PM R -JT - PM & R : the journal of injury, function, and rehabilitation -JID - 101491319 -SB - IM -MH - Cardiovascular Diseases/*prevention & control -MH - Cardiovascular Physiological Phenomena -MH - Exercise/*physiology -MH - Exercise Tolerance/physiology -MH - Heart Rate/physiology -MH - Heart Transplantation/*rehabilitation -MH - Humans -MH - Muscle Strength/physiology -MH - Muscle Stretching Exercises -MH - Physical Exertion/physiology -MH - Physical Fitness/physiology -MH - Postural Balance/physiology -MH - Primary Prevention -MH - Quality of Life -MH - Resistance Training -MH - Respiratory Physiological Phenomena -MH - Secondary Prevention -EDAT- 2012/11/24 06:00 -MHDA- 2013/05/28 06:00 -CRDT- 2012/11/24 06:00 -PHST- 2012/10/05 00:00 [received] -PHST- 2012/10/05 00:00 [accepted] -PHST- 2012/11/24 06:00 [entrez] -PHST- 2012/11/24 06:00 [pubmed] -PHST- 2013/05/28 06:00 [medline] -AID - S1934-1482(12)01631-0 [pii] -AID - 10.1016/j.pmrj.2012.10.003 [doi] -PST - ppublish -SO - PM R. 2012 Nov;4(11):867-73. doi: 10.1016/j.pmrj.2012.10.003. - -PMID- 22172788 -OWN - NLM -STAT- MEDLINE -DCOM- 20120416 -LR - 20220408 -IS - 1876-7591 (Electronic) -IS - 1876-7591 (Linking) -VI - 4 -IP - 12 -DP - 2011 Dec -TI - Stress myocardial perfusion imaging for assessing prognosis: an update. -PG - 1305-19 -LID - 10.1016/j.jcmg.2011.10.003 [doi] -AB - A strength of nuclear myocardial perfusion imaging (MPI) is the wealth of - prognostic data accumulated over 30 years of experience with this technique. - Nuclear MPI can predict outcomes and guide revascularization decisions in - symptomatic patients and is well validated in special populations such as - patients with diabetes and chronic renal disease. Known limitations, such as - underestimation of ischemia and radiation burden, are being progressively reduced - through advances such as positron emission tomography absolute flow - quantification and fusion with computed tomography, new camera hardware and - software, and stress-only protocols. Advanced statistical techniques and - increasing focus on comparative effectiveness and appropriateness will continue - to optimize nuclear cardiology going forward. -CI - Copyright © 2011 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Bourque, Jamieson M -AU - Bourque JM -AD - Cardiovascular Division, Cardiovascular Imaging Center, Department of Medicine, - University of Virginia Health System, 1215 Lee Street, Charlottesville, VA 22908, - USA. jbourque@virginia.edu -FAU - Beller, George A -AU - Beller GA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - JACC Cardiovasc Imaging -JT - JACC. Cardiovascular imaging -JID - 101467978 -RN - 0 (Radiopharmaceuticals) -SB - IM -MH - *Coronary Circulation -MH - Evidence-Based Medicine -MH - Heart Diseases/*diagnostic imaging/physiopathology/therapy -MH - Humans -MH - Multimodal Imaging -MH - Myocardial Perfusion Imaging/*methods -MH - *Positron-Emission Tomography -MH - Predictive Value of Tests -MH - Prognosis -MH - Radiopharmaceuticals -MH - Severity of Illness Index -MH - *Tomography, Emission-Computed, Single-Photon -MH - Tomography, X-Ray Computed -EDAT- 2011/12/17 06:00 -MHDA- 2012/04/17 06:00 -CRDT- 2011/12/17 06:00 -PHST- 2011/08/24 00:00 [received] -PHST- 2011/10/21 00:00 [revised] -PHST- 2011/10/27 00:00 [accepted] -PHST- 2011/12/17 06:00 [entrez] -PHST- 2011/12/17 06:00 [pubmed] -PHST- 2012/04/17 06:00 [medline] -AID - S1936-878X(11)00740-6 [pii] -AID - 10.1016/j.jcmg.2011.10.003 [doi] -PST - ppublish -SO - JACC Cardiovasc Imaging. 2011 Dec;4(12):1305-19. doi: 10.1016/j.jcmg.2011.10.003. - -PMID- 20965888 -OWN - NLM -STAT- MEDLINE -DCOM- 20111207 -LR - 20161125 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 31 -IP - 24 -DP - 2010 Dec -TI - Assessment of myocardial ischaemia and viability: role of positron emission - tomography. -PG - 2984-95 -LID - 10.1093/eurheartj/ehq361 [doi] -AB - In developed countries, coronary artery disease (CAD) continues to be a major - cause of death and disability. Over the past two decades, positron emission - tomography (PET) imaging has become more widely accessible for the management of - ischemic heart disease. Positron emission tomography has also emerged as an - important alternative perfusion imaging modality in the context of recent - shortages of molybdenum-99/technetium-99m ((99m)Tc). The clinical application of - PET in ischaemic heart disease falls into two main categories: first, it is a - well-established modality for evaluation of myocardial blood flow (MBF); second, - it enables assessment of myocardial metabolism and viability in patients with - ischaemic left ventricular dysfunction. The combined study of MBF and metabolism - by PET has led to a better understanding of the pathophysiology of ischaemic - heart disease. While there are potential future applications of PET for plaque - and molecular imaging, as well as some clinical use in inflammatory conditions, - this article provides an overview of the physical and biological principles - behind PET imaging and its main clinical applications in cardiology, namely the - assessment of MBF and metabolism. -FAU - Ghosh, Nina -AU - Ghosh N -AD - National Cardiac PET Centre, Division of Cardiology and the Molecular Function - and Imaging Program, University of Ottawa Heart Institute, Ottawa, ONT, Canada. -FAU - Rimoldi, Ornella E -AU - Rimoldi OE -FAU - Beanlands, Rob S B -AU - Beanlands RS -FAU - Camici, Paolo G -AU - Camici PG -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20101021 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (Radiopharmaceuticals) -RN - 0Z5B2CJX4D (Fluorodeoxyglucose F18) -SB - IM -MH - Fluorodeoxyglucose F18 -MH - Humans -MH - Kaplan-Meier Estimate -MH - Myocardial Ischemia/*diagnostic imaging/mortality -MH - Myocardial Perfusion Imaging/methods -MH - Myocardial Revascularization/methods -MH - Positron-Emission Tomography/*methods -MH - Prognosis -MH - Radiopharmaceuticals -EDAT- 2010/10/23 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2010/10/23 06:00 -PHST- 2010/10/23 06:00 [entrez] -PHST- 2010/10/23 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -AID - ehq361 [pii] -AID - 10.1093/eurheartj/ehq361 [doi] -PST - ppublish -SO - Eur Heart J. 2010 Dec;31(24):2984-95. doi: 10.1093/eurheartj/ehq361. Epub 2010 - Oct 21. - -PMID- 17699208 -OWN - NLM -STAT- MEDLINE -DCOM- 20070830 -LR - 20071115 -IS - 1555-905X (Electronic) -IS - 1555-9041 (Linking) -VI - 1 -IP - 2 -DP - 2006 Mar -TI - Heart failure and nephropathy: catastrophic and interrelated complications of - diabetes. -PG - 193-208 -AB - Heart failure (HF) is a major contributor to poor quality of life, a leading - cause of hospitalization, and cause of premature death. Both kidney disease and - diabetes are major and independent risk factors for the development of heart - failure, such that individuals with diabetic nephropathy are at especially high - risk. Such patients not only are likely to have coronary artery disease and - hypertension but also are likely to have diabetic cardiomyopathy, a distinct - pathologic entity that is more closely associated with the microvascular than the - macrovascular complications of diabetes. In addition to a better understanding of - the epidemiology of HF, advances in noninvasive imaging have highlighted the - importance of early cardiac dysfunction in diabetes and the high prevalence of HF - with preserved left ventricular systolic function. Although significant renal - dysfunction is usually an exclusion criterion in HF trials, diabetes is often a - prespecified subgroup so that subanalyses of large multicenter clinical trials do - provide some guidance in therapeutic decision-making. However, further therapies - for both HF and nephropathy in diabetes clearly are needed, and a number of new - therapeutic strategies that target both disorders have already entered the - clinical arena. -FAU - Gilbert, Richard E -AU - Gilbert RE -AD - University of Melbourne Department of Medicine, St. Vincent's Hospital, Victoria, - Australia. gilbert@medstv.unimelb.edu.au -FAU - Connelly, Kim -AU - Connelly K -FAU - Kelly, Darren J -AU - Kelly DJ -FAU - Pollock, Carol A -AU - Pollock CA -FAU - Krum, Henry -AU - Krum H -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20051207 -PL - United States -TA - Clin J Am Soc Nephrol -JT - Clinical journal of the American Society of Nephrology : CJASN -JID - 101271570 -SB - IM -MH - Catastrophic Illness -MH - Diabetes Complications/diagnosis/epidemiology/*etiology/therapy -MH - Heart Failure/diagnosis/epidemiology/*etiology/therapy -MH - Humans -RF - 156 -EDAT- 2007/08/21 09:00 -MHDA- 2007/08/31 09:00 -CRDT- 2007/08/21 09:00 -PHST- 2007/08/21 09:00 [pubmed] -PHST- 2007/08/31 09:00 [medline] -PHST- 2007/08/21 09:00 [entrez] -AID - CJN.00540705 [pii] -AID - 10.2215/CJN.00540705 [doi] -PST - ppublish -SO - Clin J Am Soc Nephrol. 2006 Mar;1(2):193-208. doi: 10.2215/CJN.00540705. Epub - 2005 Dec 7. - -PMID- 20403266 -OWN - NLM -STAT- MEDLINE -DCOM- 20100623 -LR - 20181201 -IS - 1603-6824 (Electronic) -IS - 0041-5782 (Linking) -VI - 172 -IP - 11 -DP - 2010 Mar 15 -TI - [Discontinuation of treatment with platelet aggregation inhibitors in surgical - patients with cardiac stents]. -PG - 852-7 -AB - Dual antiplatelet therapy with aspirin and clopidogrel is increasingly used for - secondary prevention of cardiovascular events in patients with percutaneous - coronary intervention. Anesthesiologists and surgeons are faced with the - challenge of managing these patients prior to a surgical procedure. Premature - discontinuation of antiplatelet therapy constitutes a substantial risk of stent - thrombosis, myocardial infarction and death. Continuing therapy increases the - risk of bleeding. We provide the latest evidence on this topic for patients - awaiting non-cardiac surgery. -FAU - Johansen, Mathias -AU - Johansen M -AD - Anaestesiologisk og Intensiv Afdeling, Hvidovre Hospital, DK-2650 Hvidovre, - Denmark. mattisboy@webspeed.dk -FAU - Afshari, Arash -AU - Afshari A -FAU - Kristensen, Billy B -AU - Kristensen BB -LA - dan -PT - Journal Article -PT - Review -TT - Pause med trombocytaggregationshaemmere hos kirurgiske patienter med kardiel - stent. -PL - Denmark -TA - Ugeskr Laeger -JT - Ugeskrift for laeger -JID - 0141730 -RN - 0 (Platelet Aggregation Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Angioplasty, Balloon, Coronary/adverse effects -MH - Aspirin/administration & dosage -MH - Blood Loss, Surgical -MH - Clopidogrel -MH - Coronary Thrombosis/etiology/prevention & control -MH - Drug Administration Schedule -MH - Drug Therapy, Combination -MH - Elective Surgical Procedures -MH - Emergencies -MH - Evidence-Based Medicine -MH - Humans -MH - Myocardial Infarction/etiology/prevention & control -MH - Platelet Aggregation Inhibitors/*administration & dosage -MH - Postoperative Hemorrhage/etiology -MH - Practice Guidelines as Topic -MH - Risk Assessment -MH - *Stents/adverse effects -MH - Ticlopidine/administration & dosage/analogs & derivatives -MH - Time Factors -RF - 30 -EDAT- 2010/04/21 06:00 -MHDA- 2010/06/24 06:00 -CRDT- 2010/04/21 06:00 -PHST- 2010/04/21 06:00 [entrez] -PHST- 2010/04/21 06:00 [pubmed] -PHST- 2010/06/24 06:00 [medline] -AID - VP06080307 [pii] -PST - ppublish -SO - Ugeskr Laeger. 2010 Mar 15;172(11):852-7. - -PMID- 21902660 -OWN - NLM -STAT- MEDLINE -DCOM- 20140127 -LR - 20191112 -IS - 1875-6182 (Electronic) -IS - 1871-5257 (Linking) -VI - 9 -IP - 4 -DP - 2011 Oct -TI - Diabetic cardiomyopathy and oxidative stress: role of antioxidants. -PG - 225-30 -AB - Diabetes has emerged as a major threat to worldwide health. The increasing - incidence of diabetes in young individuals is particularly worrisome given that - the disease is likely to evolve over a period of years. In 1972, the existence of - a diabetic cardiomyopathy was proposed based on the experience with four adult - diabetic patients who suffered from congestive heart failure in the absence of - discernible coronary artery disease, valvular or congenital heart disease, - hypertension, or alcoholism. The exact mechanisms underlying the disease are - unknown; however, there is growing evidence that excess generation of highly - reactive free radicals, largely due to hyperglycemia, causes oxidative stress, - which further exacerbates the development and progression of diabetes and its - complications. Hyperglycemiainduced oxidative stress is a major risk factor for - the development of micro-vascular pathogenesis in the diabetic myocardium, which - results in myocardial cell death, hypertrophy, fibrosis, abnormalities of calcium - homeostasis and endothelial dysfunction. In this review, we provide the emergence - of experimental evidence supporting antioxidant supplementation as a - cardioprotective intervention in the setting of diabetic cardiomyopathy. -FAU - Thandavarayan, Rajarajan A -AU - Thandavarayan RA -AD - Department of Functional and Analytical Food Sciences, Niigata University of - Pharmacy and Applied Life Sciences NUPALS, Higashijima 265-1 Akiha-Ku, Niigata, - 956-8603, Japan. -FAU - Giridharan, Vijayasree V -AU - Giridharan VV -FAU - Watanabe, Kenichi -AU - Watanabe K -FAU - Konishi, Tetsuya -AU - Konishi T -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Netherlands -TA - Cardiovasc Hematol Agents Med Chem -JT - Cardiovascular & hematological agents in medicinal chemistry -JID - 101266881 -RN - 0 (Antioxidants) -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Animals -MH - Antioxidants/pharmacology/*therapeutic use -MH - Cardiotonic Agents/pharmacology/*therapeutic use -MH - Diabetic Cardiomyopathies/*drug therapy/metabolism/pathology -MH - Heart/drug effects -MH - Humans -MH - Myocardium/metabolism/pathology -MH - Oxidative Stress/*drug effects -EDAT- 2011/09/10 06:00 -MHDA- 2014/01/28 06:00 -CRDT- 2011/09/10 06:00 -PHST- 2011/05/25 00:00 [received] -PHST- 2011/06/07 00:00 [accepted] -PHST- 2011/09/10 06:00 [entrez] -PHST- 2011/09/10 06:00 [pubmed] -PHST- 2014/01/28 06:00 [medline] -AID - EPub-Abstract-CHA-MC-43 [pii] -AID - 10.2174/187152511798120877 [doi] -PST - ppublish -SO - Cardiovasc Hematol Agents Med Chem. 2011 Oct;9(4):225-30. doi: - 10.2174/187152511798120877. - -PMID- 22185868 -OWN - NLM -STAT- MEDLINE -DCOM- 20120306 -LR - 20231112 -IS - 1474-547X (Electronic) -IS - 0140-6736 (Print) -IS - 0140-6736 (Linking) -VI - 379 -IP - 9817 -DP - 2012 Feb 25 -TI - Myocarditis. -PG - 738-47 -LID - 10.1016/S0140-6736(11)60648-X [doi] -AB - Myocarditis is an underdiagnosed cause of acute heart failure, sudden death, and - chronic dilated cardiomyopathy. In developed countries, viral infections commonly - cause myocarditis; however, in the developing world, rheumatic carditis, - Trypanosoma cruzi, and bacterial infections such as diphtheria still contribute - to the global burden of the disease. The short-term prognosis of acute - myocarditis is usually good, but varies widely by cause. Those patients who - initially recover might develop recurrent dilated cardiomyopathy and heart - failure, sometimes years later. Because myocarditis presents with non-specific - symptoms including chest pain, dyspnoea, and palpitations, it often mimics more - common disorders such as coronary artery disease. In some patients, cardiac MRI - and endomyocardial biopsy can help identify myocarditis, predict risk of - cardiovascular events, and guide treatment. Finding effective therapies has been - challenging because the pathogenesis of chronic dilated cardiomyopathy after - viral myocarditis is complex and determined by host and viral genetics as well as - environmental factors. Findings from recent clinical trials suggest that some - patients with chronic inflammatory cardiomyopathy have a progressive clinical - course despite standard medical care and might improve with a short course of - immunosuppression. -CI - Copyright © 2012 Elsevier Ltd. All rights reserved. -FAU - Sagar, Sandeep -AU - Sagar S -AD - Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA. -FAU - Liu, Peter P -AU - Liu PP -FAU - Cooper, Leslie T Jr -AU - Cooper LT Jr -LA - eng -GR - R01 HL056267/HL/NHLBI NIH HHS/United States -GR - R56 HL056267/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Review -DEP - 20111218 -PL - England -TA - Lancet -JT - Lancet (London, England) -JID - 2985213R -SB - IM -MH - Acute Disease -MH - Bacterial Infections/complications -MH - Humans -MH - *Myocarditis/diagnosis/etiology/physiopathology/therapy -MH - Prognosis -MH - Virus Diseases/complications -PMC - PMC5814111 -MID - NIHMS940696 -COIS- Conflicts of interest PPL ans SS declare that they have no conflicts of interest. - LTC has received consultancy fees from Sanofi Pasteur. -EDAT- 2011/12/22 06:00 -MHDA- 2012/03/07 06:00 -PMCR- 2018/02/15 -CRDT- 2011/12/22 06:00 -PHST- 2011/12/22 06:00 [entrez] -PHST- 2011/12/22 06:00 [pubmed] -PHST- 2012/03/07 06:00 [medline] -PHST- 2018/02/15 00:00 [pmc-release] -AID - S0140-6736(11)60648-X [pii] -AID - 10.1016/S0140-6736(11)60648-X [doi] -PST - ppublish -SO - Lancet. 2012 Feb 25;379(9817):738-47. doi: 10.1016/S0140-6736(11)60648-X. Epub - 2011 Dec 18. - -PMID- 21276490 -OWN - NLM -STAT- MEDLINE -DCOM- 20140929 -LR - 20110131 -IS - 1579-2242 (Electronic) -IS - 0300-8932 (Linking) -VI - 64 Suppl 1 -DP - 2011 -TI - [Update in ischemic heart disease]. -PG - 50-8 -AB - This article contains a review of the main developments reported in 2010 - concerning the pathophysiology, prevention, prognosis and treatment of ST-segment - elevation and non-ST-segment elevation acute coronary syndromes, and of - recommendations made by the most recent clinical practice guidelines. -CI - Copyright © 2011 Sociedad Española de Cardiología. Published by Elsevier Espana. - All rights reserved. -FAU - Barrabés, José A -AU - Barrabés JA -AD - Servicio de Cardiología, Hospital Universitario Vall d'Hebron, Universidad - Autónoma de Barcelona, Barcelona, España. -FAU - Bodí, Vicente -AU - Bodí V -FAU - Jiménez-Candil, Javier -AU - Jiménez-Candil J -FAU - Fernández-Ortiz, Antonio -AU - Fernández-Ortiz A -LA - spa -PT - English Abstract -PT - Journal Article -PT - Review -TT - Actualización en cardiopatía isquémica. -PL - Spain -TA - Rev Esp Cardiol -JT - Revista espanola de cardiologia -JID - 0404277 -RN - 0 (Fibrinolytic Agents) -SB - IM -MH - Arrhythmias, Cardiac/etiology -MH - Fibrinolytic Agents/therapeutic use -MH - Humans -MH - Myocardial Ischemia/epidemiology/physiopathology/prevention & control/*therapy -MH - Secondary Prevention -EDAT- 2011/02/01 06:00 -MHDA- 2014/09/30 06:00 -CRDT- 2011/02/01 06:00 -PHST- 2011/02/01 06:00 [entrez] -PHST- 2011/02/01 06:00 [pubmed] -PHST- 2014/09/30 06:00 [medline] -AID - S0300-8932(11)70007-0 [pii] -AID - 10.1016/S0300-8932(11)70007-0 [doi] -PST - ppublish -SO - Rev Esp Cardiol. 2011;64 Suppl 1:50-8. doi: 10.1016/S0300-8932(11)70007-0. - -PMID- 18490430 -OWN - NLM -STAT- MEDLINE -DCOM- 20081112 -LR - 20220409 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 29 -IP - 12 -DP - 2008 Jun -TI - Effect of atrial natriuretic peptide on left ventricular remodelling in patients - with acute myocardial infarction. -PG - 1485-94 -LID - 10.1093/eurheartj/ehn206 [doi] -AB - Atrial natriuretic peptide (ANP) is a member of the natriuretic peptide family - that exerts various biological effects via acting on the receptor-guanylyl - cyclase system, increasing the content of intracellular cyclic guanosine - monophosphate (cGMP). ANP was first identified as a diuretic/natriuretic and - vasodilating hormone, but subsequent studies revealed that ANP has a very - important function in the inhibition of the renin-angiotensin-aldosterone system - (RAAS), endothelin synthesis, and sympathetic nerve activity. Evidence is also - accumulating from recent work that ANP exerts its cardioprotective functions not - only as a circulating hormone but also as a local autocrine and/or paracrine - factor. ANP inhibits apoptosis and hypertrophy of cardiac myocytes, and inhibits - proliferation and fibrosis of cardiac fibroblasts. Reperfusion of the ischaemic - myocardium by percutaneous coronary intervention (PCI) reduces the infarct size - and improves left ventricular (LV) function in patients with acute myocardial - infarction (AMI). However, the benefits of PCI in AMI are limited by reperfusion - injury. Animal studies have shown that ANP inhibits ischaemia/reperfusion injury, - and reduces infarct size. We and others have recently shown that the intravenous - administration of ANP inhibits RAAS, sympathetic nerve activity and reperfusion - injury, prevents LV remodelling, and improves LV function in patients with AMI. - ANP has a variety of cardioprotective effects and is considered to be a very - promising adjunct drug for the reperfusion therapy in patients with AMI. -FAU - Kasama, Shu -AU - Kasama S -AD - Department of Cardiovascular Medicine, Gunma University School of Medicine, - 3-39-15 Showa-machi, Maebashi, Gunma 371-0034, Japan. s-kasama@bay.wind.ne.jp -FAU - Furuya, Mayumi -AU - Furuya M -FAU - Toyama, Takuji -AU - Toyama T -FAU - Ichikawa, Shuichi -AU - Ichikawa S -FAU - Kurabayashi, Masahiko -AU - Kurabayashi M -LA - eng -PT - Journal Article -PT - Review -DEP - 20080519 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 85637-73-6 (Atrial Natriuretic Factor) -SB - IM -MH - Angioplasty, Balloon, Coronary/adverse effects -MH - Animals -MH - Atrial Natriuretic Factor/*administration & dosage/pharmacology -MH - Disease Models, Animal -MH - Dogs -MH - Humans -MH - Myocardial Infarction/*therapy -MH - Myocardial Reperfusion Injury/prevention & control -MH - Rabbits -MH - Rats -MH - Renin-Angiotensin System/drug effects -MH - Sympathetic Nervous System/drug effects -MH - Ventricular Remodeling/*drug effects -RF - 85 -EDAT- 2008/05/21 09:00 -MHDA- 2008/11/13 09:00 -CRDT- 2008/05/21 09:00 -PHST- 2008/05/21 09:00 [pubmed] -PHST- 2008/11/13 09:00 [medline] -PHST- 2008/05/21 09:00 [entrez] -AID - ehn206 [pii] -AID - 10.1093/eurheartj/ehn206 [doi] -PST - ppublish -SO - Eur Heart J. 2008 Jun;29(12):1485-94. doi: 10.1093/eurheartj/ehn206. Epub 2008 - May 19. - -PMID- 19702121 -OWN - NLM -STAT- MEDLINE -DCOM- 20091001 -LR - 20091109 -IS - 0025-8105 (Print) -IS - 0025-8105 (Linking) -VI - 62 Suppl 3 -DP - 2009 -TI - [Anatomic distribution of peripheral atherosclerosis and its correlation with - lipid disorders]. -PG - 75-9 -AB - The peripheral arterial occlusive disease (PAOD) of the lower extremities caused - by atherosclerosis is usually associated with the one in the coronary and - cerebral arteries. Life expectancy of patients having PAOD is shorter for about - 10 years and most of these patients die from a heart disease or insult. Arterial - occlusive Such a multi-segment disease is also associated with the poorer general - cardiovascular health condition and higher morbidity and mortality than in the - case of a localized one-segment disease. Numerous studies have shown that the - etiology of a disease in the changes in the legs usually develop at several - levels within the arteries, but it is possible to localize them only in one - limited region in the vessel. When stenosis is found on several places, the blood - flow in the lower extremities is often very compromised, and ischaemia of the - legs may become an important clinical problem. lower extremities may vary - depending on the anatomic site of me lesion. Aorto-iliac disease seems to develop - in younger patients who smoke, whereas a more distal lesion in the infrapopliteal - arteries is primarily found in diabetic patients. -FAU - Tesić, Dragan S -AU - Tesić DS -AD - Klinicka centar Vojvodine, Novi Sad. drtesic@EUnet.rs -LA - srp -PT - English Abstract -PT - Journal Article -PT - Review -PL - Serbia -TA - Med Pregl -JT - Medicinski pregled -JID - 2985249R -SB - IM -MH - Atherosclerosis/complications/*pathology -MH - Humans -MH - Hyperlipidemias/*complications -MH - Leg/*blood supply -MH - Peripheral Vascular Diseases/etiology/*pathology -MH - Risk Factors -MH - Smoking/adverse effects -RF - 34 -EDAT- 2009/08/26 09:00 -MHDA- 2009/10/02 06:00 -CRDT- 2009/08/26 09:00 -PHST- 2009/08/26 09:00 [entrez] -PHST- 2009/08/26 09:00 [pubmed] -PHST- 2009/10/02 06:00 [medline] -PST - ppublish -SO - Med Pregl. 2009;62 Suppl 3:75-9. - -PMID- 18467804 -OWN - NLM -STAT- MEDLINE -DCOM- 20080624 -LR - 20080509 -IS - 0032-5481 (Print) -IS - 0032-5481 (Linking) -VI - 120 -IP - 1 -DP - 2008 Apr -TI - Office care of patients after myocardial infarction. -PG - 11-7 -LID - 10.3810/pgm.2008.04.1755 [doi] -AB - Declining death rates from heart disease since the 1950s have been largely - attributed to secondary prevention. Unfortunately, studies demonstrate remarkable - underutilization of secondary prevention plans by health care providers. Health - care providers should develop secondary prevention plans for patients who have - sustained a myocardial infarction or an acute coronary syndrome. The secondary - prevention plan should include four core components: initial patient risk - assessment, pharmacologic therapy, therapeutic lifestyle changes and - intervention, and psychosocial evaluation. -FAU - Derby, Richard C -AU - Derby RC -AD - Department of Family Medicine, Uniformed Services University, Bethesda, MD 20762, - USA. richard.derby-02@afnrc.af.mil -FAU - Reamy, Brian V -AU - Reamy BV -FAU - Plumley, Ray L -AU - Plumley RL -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Postgrad Med -JT - Postgraduate medicine -JID - 0401147 -SB - IM -MH - Cost of Illness -MH - Humans -MH - Life Style -MH - Myocardial Infarction/drug therapy/prevention & control/*therapy -MH - *Primary Health Care -MH - Risk Assessment -RF - 26 -EDAT- 2008/05/10 09:00 -MHDA- 2008/06/25 09:00 -CRDT- 2008/05/10 09:00 -PHST- 2008/05/10 09:00 [pubmed] -PHST- 2008/06/25 09:00 [medline] -PHST- 2008/05/10 09:00 [entrez] -AID - 10.3810/pgm.2008.04.1755 [doi] -PST - ppublish -SO - Postgrad Med. 2008 Apr;120(1):11-7. doi: 10.3810/pgm.2008.04.1755. - -PMID- 16413381 -OWN - NLM -STAT- MEDLINE -DCOM- 20060411 -LR - 20060117 -IS - 0146-2806 (Print) -IS - 0146-2806 (Linking) -VI - 31 -IP - 2 -DP - 2006 Feb -TI - Contrast-enhanced cardiac magnetic resonance in the evaluation of myocardial - infarction and myocardial viability in patients with ischemic heart disease. -PG - 128-68 -FAU - Bucciarelli-Ducci, Chiara -AU - Bucciarelli-Ducci C -AD - Division of Cardiology, Northwestern University Feinberg School of Medicine, - Chicago, IL 60611, USA. -FAU - Wu, Edwin -AU - Wu E -FAU - Lee, Daniel C -AU - Lee DC -FAU - Holly, Thomas A -AU - Holly TA -FAU - Klocke, Francis J -AU - Klocke FJ -FAU - Bonow, Robert O -AU - Bonow RO -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Curr Probl Cardiol -JT - Current problems in cardiology -JID - 7701802 -RN - 0 (Contrast Media) -SB - IM -MH - Animals -MH - Contrast Media -MH - Coronary Circulation -MH - Diagnosis, Differential -MH - Humans -MH - *Image Enhancement -MH - Image Interpretation, Computer-Assisted -MH - *Magnetic Resonance Imaging/methods -MH - Myocardial Infarction/*pathology/*physiopathology -MH - Myocardial Ischemia/pathology/physiopathology -MH - Ventricular Dysfunction, Left/pathology/physiopathology -MH - Ventricular Remodeling -RF - 89 -EDAT- 2006/01/18 09:00 -MHDA- 2006/04/12 09:00 -CRDT- 2006/01/18 09:00 -PHST- 2006/01/18 09:00 [pubmed] -PHST- 2006/04/12 09:00 [medline] -PHST- 2006/01/18 09:00 [entrez] -AID - S0146-2806(05)00166-0 [pii] -AID - 10.1016/j.cpcardiol.2005.10.002 [doi] -PST - ppublish -SO - Curr Probl Cardiol. 2006 Feb;31(2):128-68. doi: 10.1016/j.cpcardiol.2005.10.002. - -PMID- 20933649 -OWN - NLM -STAT- MEDLINE -DCOM- 20101112 -LR - 20250529 -IS - 1365-229X (Electronic) -IS - 0009-9260 (Linking) -VI - 65 -IP - 11 -DP - 2010 Nov -TI - Complications of myocardial infarction on multidetector-row computed tomography - of chest. -PG - 930-6 -LID - 10.1016/j.crad.2010.03.017 [doi] -AB - Myocardial infarction (MI) secondary to coronary artery disease remains the - leading cause of death in the western world. The advent of early reperfusion - therapy has substantially decreased in-hospital mortality and has improved the - outcome in survivors of the acute phase of MI. Complications of MI include - ischaemic, mechanical, arrhythmic, embolic and inflammatory disturbances. - Although some of these complications may be infrequent, their importance is - underscored because of the potential ability to correct them with early diagnosis - and appropriate treatment. The majority of these complications will be detected - on clinical examination and confirmed by echocardiography. Some patients may - undergo non-electrocardiogram (ECG)-gated thoracic multidetector-row computed - tomography (MDCT) due to non-specific presentation. In this group, it is - imperative for the radiologist to be aware of and be confident in diagnosing the - complications secondary to MI. This review illustrates the spectrum and imaging - features of acute and chronic complications of MI that can be visualized on both - ECG-gated cardiac and non-ECG-gated thoracic MDCT. -CI - Copyright © 2010 The Royal College of Radiologists. Published by Elsevier Ltd. - All rights reserved. -FAU - Raj, V -AU - Raj V -AD - Department of Radiology, Papworth and Addenbrookes Hospital, Cambridge, UK. -FAU - Karunasaagarar, K -AU - Karunasaagarar K -FAU - Rudd, J H F -AU - Rudd JH -FAU - Screaton, N -AU - Screaton N -FAU - Gopalan, D -AU - Gopalan D -LA - eng -GR - PG/09/083/27667/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Review -DEP - 20100804 -PL - England -TA - Clin Radiol -JT - Clinical radiology -JID - 1306016 -SB - IM -MH - Coronary Angiography -MH - Electrocardiography/methods -MH - Hospital Mortality -MH - Humans -MH - Myocardial Infarction/*complications/diagnostic imaging -MH - Tomography, X-Ray Computed/methods -EDAT- 2010/10/12 06:00 -MHDA- 2010/11/13 06:00 -CRDT- 2010/10/12 06:00 -PHST- 2009/12/23 00:00 [received] -PHST- 2010/03/19 00:00 [revised] -PHST- 2010/03/22 00:00 [accepted] -PHST- 2010/10/12 06:00 [entrez] -PHST- 2010/10/12 06:00 [pubmed] -PHST- 2010/11/13 06:00 [medline] -AID - S0009-9260(10)00239-4 [pii] -AID - 10.1016/j.crad.2010.03.017 [doi] -PST - ppublish -SO - Clin Radiol. 2010 Nov;65(11):930-6. doi: 10.1016/j.crad.2010.03.017. Epub 2010 - Aug 4. - -PMID- 19207780 -OWN - NLM -STAT- MEDLINE -DCOM- 20091015 -LR - 20090728 -IS - 1540-8167 (Electronic) -IS - 1045-3873 (Linking) -VI - 20 -IP - 6 -DP - 2009 Jun -TI - Strategies for epicardial mapping and ablation of ventricular tachycardia. -PG - 710-3 -LID - 10.1111/j.1540-8167.2008.01427.x [doi] -AB - Catheter ablation for ventricular tachycardia (VT) is becoming an essential - component of the successful management of patients with structural heart disease - and refractory ventricular arrhythmias. Despite detailed mapping and ablation - from the endocardium, nearly a third of VT circuits remain inaccessible. - Pericardial access has improved our ability to address these resistant VTs. - Adhesions after cardiac surgery can impede access, necessitating a direct - surgical approach to the pericardial space. Potential risks include risk of - injury to an epicardial coronary artery, the phrenic nerve, subdiaphragmatic - vessels, and right ventricle. We describe the indications for and approach to - catheter ablation of VT for the pericardial space. -FAU - Tedrow, Usha -AU - Tedrow U -AD - Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, - Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. - utedrow@partners.org -FAU - Stevenson, William G -AU - Stevenson WG -LA - eng -PT - Journal Article -PT - Review -DEP - 20090202 -PL - United States -TA - J Cardiovasc Electrophysiol -JT - Journal of cardiovascular electrophysiology -JID - 9010756 -SB - IM -MH - Body Surface Potential Mapping/*methods -MH - Catheter Ablation/*methods -MH - Heart Conduction System/*surgery -MH - Humans -MH - Pericardium/*surgery -MH - Surgery, Computer-Assisted/*methods -MH - Tachycardia, Ventricular/*diagnosis/*surgery -RF - 7 -EDAT- 2009/02/12 09:00 -MHDA- 2009/10/16 06:00 -CRDT- 2009/02/12 09:00 -PHST- 2009/02/12 09:00 [entrez] -PHST- 2009/02/12 09:00 [pubmed] -PHST- 2009/10/16 06:00 [medline] -AID - JCE1427 [pii] -AID - 10.1111/j.1540-8167.2008.01427.x [doi] -PST - ppublish -SO - J Cardiovasc Electrophysiol. 2009 Jun;20(6):710-3. doi: - 10.1111/j.1540-8167.2008.01427.x. Epub 2009 Feb 2. - -PMID- 19273197 -OWN - NLM -STAT- MEDLINE -DCOM- 20090407 -LR - 20220227 -IS - 2768-6698 (Electronic) -IS - 2768-6698 (Linking) -VI - 14 -IP - 6 -DP - 2009 Jan 1 -TI - Role of oxidative and nitrosative stress biomarkers in chronic heart failure. -PG - 2230-7 -LID - 10.2741/3375 [doi] -AB - In this review, we present recent insights on chronic heart failure (CHF) and the - potential role of tumor necrosis factor (TNF)-alpha, interleukins, - myeloperoxidase (MPO), and nitrosative stress in the progression of this disease - process. Reactive oxygen species (ROS) are produced as a consequence of aerobic - metabolism. Under physiologic conditions, their unfavourable effect in causing - oxidative damage is counteracted by antioxidants. An imbalance in favour of - oxidants leads to oxidative stress, and contributes to myocyte apoptosis, direct - negative inotropic effects, and reduced bioavailability of nitric oxide (NO). - Together, these effects lead to impaired vasodilatation of the coronary, - pulmonary and peripheral vascular beds. In patients with moderate to severe forms - of CHF, TNF-alpha leads to the formation of nitrotyrosine and consumption of - nitric oxide by virtue of activation of myeloperoxidase. Further studies are - required to better elucidate the complex interaction of oxidative stress, - endothelial dysfunction and inflammatory activation in CHF. Such insights would - likely lead to development of better strategies for the assessment of the disease - severity by monitoring of new bio-humoral indices and better treatment - approaches. -FAU - Eleuteri, Ermanno -AU - Eleuteri E -AD - Cardiology Unit and Laboratory of Cytoimmunopathology, Fondazione Salvatore - Maugeri, IRCCS, Via per Revislate 13, Veruno (NO), Italy. ermanno.eleuteri@fsm.it -FAU - Magno, Francesca -AU - Magno F -FAU - Gnemmi, Isabella -AU - Gnemmi I -FAU - Carbone, Marco -AU - Carbone M -FAU - Colombo, Marilena -AU - Colombo M -FAU - La Rocca, Giampiero -AU - La Rocca G -FAU - Anzalone, Rita -AU - Anzalone R -FAU - Tarro Genta, Francesco -AU - Tarro Genta F -FAU - Zummo, Giovanni -AU - Zummo G -FAU - Di Stefano, Antonino -AU - Di Stefano A -FAU - Giannuzzi, Pantaleo -AU - Giannuzzi P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090101 -PL - Singapore -TA - Front Biosci (Landmark Ed) -JT - Frontiers in bioscience (Landmark edition) -JID - 101612996 -RN - 0 (Biomarkers) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - EC 1.11.1.7 (Peroxidase) -SB - IM -MH - Biomarkers/*metabolism -MH - Chronic Disease -MH - Endothelium, Vascular/physiopathology -MH - Heart Failure/enzymology/*metabolism -MH - Humans -MH - Natriuretic Peptide, Brain/metabolism -MH - *Nitrosation -MH - *Oxidative Stress -MH - Peroxidase/metabolism -RF - 38 -EDAT- 2009/03/11 09:00 -MHDA- 2009/04/08 09:00 -CRDT- 2009/03/11 09:00 -PHST- 2009/03/11 09:00 [entrez] -PHST- 2009/03/11 09:00 [pubmed] -PHST- 2009/04/08 09:00 [medline] -AID - 3375 [pii] -AID - 10.2741/3375 [doi] -PST - epublish -SO - Front Biosci (Landmark Ed). 2009 Jan 1;14(6):2230-7. doi: 10.2741/3375. - -PMID- 17556206 -OWN - NLM -STAT- MEDLINE -DCOM- 20070918 -LR - 20161222 -IS - 1547-5271 (Print) -IS - 1547-5271 (Linking) -VI - 4 -IP - 6 -DP - 2007 Jun -TI - New concepts for old drugs to maintain sinus rhythm in patients with atrial - fibrillation. -PG - 790-3 -AB - Atrial fibrillation (AF) is a chronic, often progressive disease. Despite the - ongoing concerted effort to improve AF therapy, often there is no remedy for - curing AF and preventing the deleterious effects of the arrhythmia on health. - Antiarrhythmic drug therapy is likely to remain the mainstay of therapy for many - patients in the foreseeable future. Available antiarrhythmic drugs are moderately - effective, which is important for patients who respond, especially given the - chronic and often progressive nature of the disease. This article describes - emerging concepts under clinical evaluation that attempt to improve the safety of - available antiarrhythmic drugs in the treatment of recurrent AF. Two concepts are - reviewed: (1) combination of an antiarrhythmic drug with a calcium channel - blocker to reduce proarrhythmic side effects, and (2) "intelligent" reduction of - the duration of antiarrhythmic drug therapy targeted to periods of symptomatic or - likely AF recurrence. -FAU - Kirchhof, Paulus -AU - Kirchhof P -AD - Department of Cardiology and Angiology, Hospital of the University of Münster, - Münster, Germany. kirchhp@uni-muenster.de -FAU - Breithardt, Günter -AU - Breithardt G -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20070125 -PL - United States -TA - Heart Rhythm -JT - Heart rhythm -JID - 101200317 -RN - 0 (Anti-Arrhythmia Agents) -SB - IM -MH - Anti-Arrhythmia Agents/*pharmacology -MH - Atrial Fibrillation/*drug therapy/physiopathology -MH - Coronary Vessels/*physiopathology -MH - Drug-Related Side Effects and Adverse Reactions -MH - Humans -MH - Time Factors -RF - 39 -EDAT- 2007/06/09 09:00 -MHDA- 2007/09/19 09:00 -CRDT- 2007/06/09 09:00 -PHST- 2006/10/28 00:00 [received] -PHST- 2007/01/15 00:00 [accepted] -PHST- 2007/06/09 09:00 [pubmed] -PHST- 2007/09/19 09:00 [medline] -PHST- 2007/06/09 09:00 [entrez] -AID - S1547-5271(07)00059-8 [pii] -AID - 10.1016/j.hrthm.2007.01.023 [doi] -PST - ppublish -SO - Heart Rhythm. 2007 Jun;4(6):790-3. doi: 10.1016/j.hrthm.2007.01.023. Epub 2007 - Jan 25. - -PMID- 22431494 -OWN - NLM -STAT- MEDLINE -DCOM- 20130408 -LR - 20121025 -IS - 1522-726X (Electronic) -IS - 1522-1946 (Linking) -VI - 80 -IP - 5 -DP - 2012 Nov 1 -TI - The science behind percutaneous hemodynamic support: a review and comparison of - support strategies. -PG - 816-29 -LID - 10.1002/ccd.24421 [doi] -AB - Patients in a variety of cardiovascular disease states may benefit from temporary - percutaneous cardiac support, including those in acute decompensated heart - failure, fulminant myocarditis, acute myocardial infarction with or without - cardiogenic shock and those undergoing high-risk percutaneous coronary - intervention. The ideal percutaneous cardiac support device is safe, easy to use - and versatile enough to meet the needs of various clinical situations and patient - cohorts. In addition, it should provide maximal hemodynamic support and - protection against myocardial ischemia. With these goals in mind, the scientific - principles that govern hemodynamic effectiveness and myocardial protection as - they pertain to acute support devices are reviewed. -CI - Copyright © 2012 Wiley Periodicals, Inc. -FAU - Burkhoff, Daniel -AU - Burkhoff D -AD - Division of Cardiology, Columbia University School of Medicine, New York, New - York, USA. db59@columbia.edu -FAU - Naidu, Srihari S -AU - Naidu SS -LA - eng -PT - Journal Article -PT - Review -DEP - 20120418 -PL - United States -TA - Catheter Cardiovasc Interv -JT - Catheterization and cardiovascular interventions : official journal of the - Society for Cardiac Angiography & Interventions -JID - 100884139 -SB - IM -MH - Animals -MH - Assisted Circulation/adverse effects/*instrumentation -MH - Cardiovascular Diseases/physiopathology/*therapy -MH - *Heart-Assist Devices/adverse effects -MH - *Hemodynamics -MH - Humans -MH - Models, Cardiovascular -MH - Prosthesis Design -MH - Treatment Outcome -MH - *Ventricular Function, Left -EDAT- 2012/03/21 06:00 -MHDA- 2013/04/09 06:00 -CRDT- 2012/03/21 06:00 -PHST- 2011/09/02 00:00 [received] -PHST- 2012/03/10 00:00 [accepted] -PHST- 2012/03/21 06:00 [entrez] -PHST- 2012/03/21 06:00 [pubmed] -PHST- 2013/04/09 06:00 [medline] -AID - 10.1002/ccd.24421 [doi] -PST - ppublish -SO - Catheter Cardiovasc Interv. 2012 Nov 1;80(5):816-29. doi: 10.1002/ccd.24421. Epub - 2012 Apr 18. - -PMID- 22321569 -OWN - NLM -STAT- MEDLINE -DCOM- 20120918 -LR - 20121115 -IS - 1471-4973 (Electronic) -IS - 1471-4892 (Linking) -VI - 12 -IP - 2 -DP - 2012 Apr -TI - Pathophysiology of saphenous vein graft failure: a brief overview of - interventions. -PG - 114-20 -LID - 10.1016/j.coph.2012.01.001 [doi] -AB - Coronary artery bypass graft surgery (CABG) is widely used for the treatment of - atheromatous stenosis of coronary arteries. However, as many as 50% of grafts - fail within 10 years after CABG due to neointima (NI) formation, a process - involving the proliferation of vascular smooth muscle cells (VSMCs) and - superimposed atherogenesis. To date no therapeutic intervention has proved - successful in treating late vein graft failure. However, several diverse - approaches aimed at preventing neointimal formation have been devised which have - yielded promising results. In this review, therefore, we will summarise the - pathophysiology of vein graft disease and then briefly consider interventional - approaches to prevent late vein graft failure which include surgical technique, - conventional pharmacology, external sheaths, cytostatic drugs and gene transfer. -CI - Copyright © 2012 Elsevier Ltd. All rights reserved. -FAU - Shukla, Nilima -AU - Shukla N -AD - Bristol Heart Institute, The University of Bristol, UK. n.shukla@bris.ac.uk -FAU - Jeremy, Jamie Y -AU - Jeremy JY -LA - eng -PT - Journal Article -PT - Review -DEP - 20120208 -PL - England -TA - Curr Opin Pharmacol -JT - Current opinion in pharmacology -JID - 100966133 -RN - 0 (Cytostatic Agents) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Animals -MH - *Coronary Artery Bypass -MH - Cytostatic Agents/therapeutic use -MH - Drug-Eluting Stents -MH - Fibrinolytic Agents/therapeutic use -MH - Genetic Therapy -MH - Graft Occlusion, Vascular/physiopathology/*prevention & control -MH - Humans -MH - Neointima/physiopathology/prevention & control -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Saphenous Vein/*transplantation -MH - Thrombosis/physiopathology/prevention & control -EDAT- 2012/02/11 06:00 -MHDA- 2012/09/19 06:00 -CRDT- 2012/02/11 06:00 -PHST- 2011/10/17 00:00 [received] -PHST- 2012/01/05 00:00 [revised] -PHST- 2012/01/06 00:00 [accepted] -PHST- 2012/02/11 06:00 [entrez] -PHST- 2012/02/11 06:00 [pubmed] -PHST- 2012/09/19 06:00 [medline] -AID - S1471-4892(12)00002-1 [pii] -AID - 10.1016/j.coph.2012.01.001 [doi] -PST - ppublish -SO - Curr Opin Pharmacol. 2012 Apr;12(2):114-20. doi: 10.1016/j.coph.2012.01.001. Epub - 2012 Feb 8. - -PMID- 22094238 -OWN - NLM -STAT- MEDLINE -DCOM- 20120829 -LR - 20220317 -IS - 2047-2412 (Electronic) -IS - 2047-2404 (Linking) -VI - 13 -IP - 1 -DP - 2012 Jan -TI - Non-invasive imaging in acute chest pain syndromes. -PG - 69-78 -LID - 10.1093/ejechocard/jer250 [doi] -AB - This review has the purpose of informing the reader about the current use of - imaging techniques in patients presenting with acute chest pain to the emergency - department. We will focus on three aspects of managing the patient with acute - chest pain: Imaging to increase the number of correct diagnoses in the acute - situation; Imaging to rule out other than coronary causes of chest pain; Use of - imaging for risk stratification once myocardial infarction has been ruled out in - the CPU. Special emphasis is given to how these management aspects are discussed - in current guidelines on the management of patients with acute chest pain or - acute coronary syndrome. -FAU - Sechtem, Udo -AU - Sechtem U -AD - Robert-Bosch-Krankenhaus, Auerbachstr. 110, 70376 Stuttgart. udo.sechtem@rbk.de -FAU - Achenbach, Stephan -AU - Achenbach S -FAU - Friedrich, Matthias -AU - Friedrich M -FAU - Wackers, Frans -AU - Wackers F -FAU - Zamorano, José L -AU - Zamorano JL -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20111117 -PL - England -TA - Eur Heart J Cardiovasc Imaging -JT - European heart journal. Cardiovascular Imaging -JID - 101573788 -SB - IM -MH - Acute Disease -MH - Aortic Diseases/*diagnosis/diagnostic imaging/pathology -MH - Chest Pain/*diagnosis/diagnostic imaging/pathology -MH - Coronary Angiography -MH - Echocardiography/*methods -MH - Humans -MH - Pericarditis/*diagnosis/diagnostic imaging/pathology -MH - Pulmonary Embolism/*diagnosis/diagnostic imaging/pathology -MH - Tomography, X-Ray Computed -EDAT- 2011/11/19 06:00 -MHDA- 2012/08/30 06:00 -CRDT- 2011/11/19 06:00 -PHST- 2011/11/19 06:00 [entrez] -PHST- 2011/11/19 06:00 [pubmed] -PHST- 2012/08/30 06:00 [medline] -AID - jer250 [pii] -AID - 10.1093/ejechocard/jer250 [doi] -PST - ppublish -SO - Eur Heart J Cardiovasc Imaging. 2012 Jan;13(1):69-78. doi: - 10.1093/ejechocard/jer250. Epub 2011 Nov 17. - -PMID- 16996825 -OWN - NLM -STAT- MEDLINE -DCOM- 20061018 -LR - 20161124 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 152 -IP - 4 -DP - 2006 Oct -TI - Left bundle-branch block artifact on single photon emission computed tomography - with technetium Tc 99m (Tc-99m) agents: mechanisms and a method to decrease - false-positive interpretations. -PG - 619-26 -AB - Myocardial perfusion scintigraphy is a well validated noninvasive method of - evaluating for significant coronary artery disease, especially in cases where - electrocardiographic changes are nondiagnostic, including left bundle-branch - block. However, such testing with a technetium Tc 99m agent is often confounded - by left ventricular septal-based false-positive perfusion defects. These defects - can be either reversible or irreversible in the septal or anteroseptal wall, - problematically then, in the territory supplied by the left anterior descending - coronary artery. Mechanisms explaining false-positive defects include decreased - perfusion via impaired microvessel flow and normal perfusion with apparent - decrease in counts in a relatively thin septum (partial-volume effect). Key - findings in myocardial perfusion images in the presence of left bundle-branch - block that define true positives (ischemia) are reversible perfusion defects - (especially at end diastole), a concomitant apical defect, and systolic - dysfunction matching the perfusion defect. -FAU - Higgins, John P -AU - Higgins JP -AD - Cardiac Stress Laboratory, Harvard Medical School, VA Boston Healthcare System, - Boston, MA, USA. john.higgins@va.gov -FAU - Williams, Gethin -AU - Williams G -FAU - Nagel, James S -AU - Nagel JS -FAU - Higgins, Johanna A -AU - Higgins JA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -RN - 7440-26-8 (Technetium) -SB - IM -MH - *Artifacts -MH - Bundle-Branch Block/*diagnostic imaging/*physiopathology -MH - *Coronary Circulation -MH - False Positive Reactions -MH - Humans -MH - *Technetium -MH - *Tomography, Emission-Computed, Single-Photon -RF - 43 -EDAT- 2006/09/26 09:00 -MHDA- 2006/10/19 09:00 -CRDT- 2006/09/26 09:00 -PHST- 2006/04/06 00:00 [received] -PHST- 2006/06/09 00:00 [accepted] -PHST- 2006/09/26 09:00 [pubmed] -PHST- 2006/10/19 09:00 [medline] -PHST- 2006/09/26 09:00 [entrez] -AID - S0002-8703(06)00557-6 [pii] -AID - 10.1016/j.ahj.2006.06.009 [doi] -PST - ppublish -SO - Am Heart J. 2006 Oct;152(4):619-26. doi: 10.1016/j.ahj.2006.06.009. - -PMID- 17469340 -OWN - NLM -STAT- MEDLINE -DCOM- 20070625 -LR - 20131121 -IS - 1405-9940 (Print) -IS - 1665-1731 (Linking) -VI - 76 Suppl 4 -DP - 2006 Oct-Dec -TI - [Metabolic support of the ischemic heart during cardiac surgery]. -PG - S121-36 -AB - We examine [IBM1] the basic principles and clinical results of the metabolic - intervention with glucose-insulin-potassium (GIK) solutions in the field of - cardiovascular surgery. On the basis of many international publications - concerning this subject, and the experience obtained in the operating room of the - Instituto Nacional de Cardiologia "Ignacio Chávez", we conclude that the - metabolic support wit GIK is a powerful system that provides very useful energy - to protect the myocardium during cardiac and non-cardiac surgery. The most recent - publications indicate their effects in reducing low output syndromes, due to - interventions on the coronary arteries, as well as producing a significant - reduction of circulating fatty acids. These effects are produced also in the - field of interventional cardiology, where GIK solutions protect the myocardium - against damage due to impaired microcirculation. It is evident that these - solutions must be utilized in higher concentrations that the initial ones, equal - to those employed in laboratory animals. On the other side, it is worthy to - remember that it has been always underlined that this treatment represents only a - protection for the myocardium. Therefore, its association with other drugs or - treatments favoring a good myocardial performance is not contraindicated--on the - contrary, it yields better results. The present review presents pharmacological - approaches, such as the use of glutamato, aspartate, piruvato, trimetazidina - ranolazine and taurine to optimize cardiac energy metabolism, for the management - of ischemic heart disease. -FAU - Luna Ortiz, Pastor -AU - Luna Ortiz P -AD - Departamento de Anestesia, Instituto Nacional de Cardiología "lgnacio Chávez", - México, D.F. pluna98@yahoo.com -FAU - Serrano Valdés, Xenia -AU - Serrano Valdés X -FAU - Rojas Pérez, Eduardo -AU - Rojas Pérez E -FAU - de Micheli, Alfredo -AU - de Micheli A -LA - spa -PT - Comparative Study -PT - English Abstract -PT - Journal Article -PT - Review -TT - Apoyo metabólico del corazón isquémico en cirugía cardíaca. -PL - Mexico -TA - Arch Cardiol Mex -JT - Archivos de cardiologia de Mexico -JID - 101126728 -RN - 0 (Fatty Acids) -RN - 0 (Insulin) -RN - 0 (glucose-insulin-potassium cardioplegic solution) -RN - IY9XDZ35W2 (Glucose) -RN - RWP5GA015D (Potassium) -SB - IM -MH - *Cardiac Surgical Procedures -MH - Coronary Circulation -MH - Energy Metabolism -MH - Fatty Acids/blood -MH - Glucose/administration & dosage/therapeutic use -MH - Humans -MH - Insulin/administration & dosage/therapeutic use -MH - Microcirculation -MH - Myocardial Ischemia/blood/drug therapy/*metabolism -MH - Myocardium/*metabolism -MH - Potassium/administration & dosage/therapeutic use -RF - 68 -EDAT- 2007/05/02 09:00 -MHDA- 2007/06/26 09:00 -CRDT- 2007/05/02 09:00 -PHST- 2007/05/02 09:00 [pubmed] -PHST- 2007/06/26 09:00 [medline] -PHST- 2007/05/02 09:00 [entrez] -PST - ppublish -SO - Arch Cardiol Mex. 2006 Oct-Dec;76 Suppl 4:S121-36. - -PMID- 21290327 -OWN - NLM -STAT- MEDLINE -DCOM- 20110701 -LR - 20161109 -IS - 0065-2598 (Print) -IS - 0065-2598 (Linking) -VI - 704 -DP - 2011 -TI - TRP channels in the cardiopulmonary vasculature. -PG - 781-810 -LID - 10.1007/978-94-007-0265-3_41 [doi] -AB - Transient receptor potential (TRP) channels are expressed in almost every human - tissue, including the heart and the vasculature. They play unique roles not only - in physiological functions but, if over-expressed, also in pathophysiological - disease states. Cardiovascular diseases are the leading cause of death in the - industrialized countries. Therefore, TRP channels are attractive drug targets for - more effective pharmacological treatments of these diseases. This review focuses - on three major cell types of the cardiovascular system: cardiomyocytes as well as - smooth muscle cells and endothelial cells from the systemic and pulmonary - circulation. TRP channels initiate multiple signals in all three cell types (e.g. - contraction, migration) and are involved in gene transcription leading to cell - proliferation or cell death. Identification of their genes has significantly - improved our knowledge of multiple signal transduction pathways in these cells. - Some TRP channels are important cellular sensors and are mostly permeable to - Ca(2+), while most other TRP channels are receptor activated and allow for the - entry of Na(+), Ca(2+) and Mg(2+). Physiological functions of TRPA, TRPC, TRPM, - TRPP and TRPV channels in the cardiovascular system, dissected by down-regulating - channel activity in isolated tissues or by the analysis of gene-deficient mouse - models, are reviewed. The involvement of TRPs as homomeric or heteromeric - channels in pathophysiological processes in the cardiovascular system like heart - failure, cardiac hypertrophy, hypertension as well as edema formation by - increased endothelial permeability will be discussed. -FAU - Dietrich, Alexander -AU - Dietrich A -AD - Walther-Straub-Institute for Pharmacology and Toxicology, School of - Medicine,Ludwig-Maximilians-University München, 80336 Munich, Germany. - alexander.dietrich@lrz.uni-muenchen.de -FAU - Gudermann, Thomas -AU - Gudermann T -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Adv Exp Med Biol -JT - Advances in experimental medicine and biology -JID - 0121103 -RN - 0 (Transient Receptor Potential Channels) -SB - IM -MH - Animals -MH - Blood Vessels/*metabolism -MH - Coronary Vessels/*metabolism -MH - Humans -MH - Lung/*blood supply -MH - Mice -MH - Rats -MH - Transient Receptor Potential Channels/*metabolism -EDAT- 2011/02/04 06:00 -MHDA- 2011/07/02 06:00 -CRDT- 2011/02/04 06:00 -PHST- 2011/02/04 06:00 [entrez] -PHST- 2011/02/04 06:00 [pubmed] -PHST- 2011/07/02 06:00 [medline] -AID - 10.1007/978-94-007-0265-3_41 [doi] -PST - ppublish -SO - Adv Exp Med Biol. 2011;704:781-810. doi: 10.1007/978-94-007-0265-3_41. - -PMID- 20149010 -OWN - NLM -STAT- MEDLINE -DCOM- 20100923 -LR - 20220311 -IS - 1540-8191 (Electronic) -IS - 0886-0440 (Linking) -VI - 25 -IP - 2 -DP - 2010 Mar -TI - Gastrointestinal complications following cardiac surgery: a comprehensive review. -PG - 188-97 -LID - 10.1111/j.1540-8191.2009.00985.x [doi] -AB - INTRODUCTION: Gastrointestinal (GI) complications following cardiac surgery are - associated with a high morbidity and mortality, prolonged hospital stay and - increased cost of hospitalization. METHODS: A literature search was carried out - using Medline for articles published in the past 30 years. Prospective and - retrospective papers that dealt with coronary artery bypass grafting (CABG), - CABG/valve operations were selected and those that dealt with thoracic and - transplant complications were excluded. RESULTS: We reviewed 151,652 patients - reported over the past 30 years; GI complications occurred on average after 1.21% - of cardiac operations and had an associated mortality of 34.1%. The most common - risk factors identified include age greater than 70 years, low cardiac output, - peripheral vascular disease, reoperative surgery, chronic renal insufficiency, - increased number of blood transfusions, prolonged cardiopulmonary bypass time, - arrhythmias, and use of an intraaortic balloon pump. A critical examination of - the available literature revealed multifactorial etiologies (often related to - hypoperfusion) leading to GI complications. Delayed diagnosis was associated with - poor outcomes. CONCLUSION: GI complications are rare events, but early diagnosis - is essential. Unfortunately few of the risk factors we have defined are specific - and are often indicators of ill patients. A low threshold to initiate laboratory - evaluation and/or imaging studies should be employed if a patient shows signs of - deviating from the normal course following cardiac surgery. -FAU - Rodriguez, Roberto -AU - Rodriguez R -AD - Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Harvard - Medical School, Boston, Massachusetts, USA. Roberto.Rodriguez@caritaschristi.org -FAU - Robich, Michael P -AU - Robich MP -FAU - Plate, Juan F -AU - Plate JF -FAU - Trooskin, Stanley Z -AU - Trooskin SZ -FAU - Sellke, Frank W -AU - Sellke FW -LA - eng -PT - Journal Article -PT - Review -DEP - 20100209 -PL - United States -TA - J Card Surg -JT - Journal of cardiac surgery -JID - 8908809 -SB - IM -MH - *Coronary Artery Bypass -MH - Early Diagnosis -MH - Gastrointestinal Diseases/diagnosis/*etiology -MH - Heart Valves/surgery -MH - Humans -MH - *Meta-Analysis as Topic -MH - Postoperative Complications/diagnosis/*etiology -MH - Risk Factors -RF - 80 -EDAT- 2010/02/13 06:00 -MHDA- 2010/09/24 06:00 -CRDT- 2010/02/13 06:00 -PHST- 2010/02/13 06:00 [entrez] -PHST- 2010/02/13 06:00 [pubmed] -PHST- 2010/09/24 06:00 [medline] -AID - JCS985 [pii] -AID - 10.1111/j.1540-8191.2009.00985.x [doi] -PST - ppublish -SO - J Card Surg. 2010 Mar;25(2):188-97. doi: 10.1111/j.1540-8191.2009.00985.x. Epub - 2010 Feb 9. - -PMID- 17896976 -OWN - NLM -STAT- MEDLINE -DCOM- 20071129 -LR - 20190823 -IS - 0929-8673 (Print) -IS - 0929-8673 (Linking) -VI - 14 -IP - 21 -DP - 2007 -TI - Structure, production and function of erythropoietin: implications for - therapeutical use in cardiovascular disease. -PG - 2278-87 -AB - Erythropoietin (EPO) is a 30,400 daltons glycoprotein, consisting of 165 amino - acids produced mainly in the kidney and in the liver and regulating - erythrocyitosis. It primarily acts on erythroid precursor cell at colony-forming - units-erythroid stage inhibiting the apoptosis. EPO binds on a specific membrane - receptor thereby activating at least three specific intracellular signaling - pathways, such as phosphatidylinositol 3-kinase/ protein kinase B, - Ras-mitogen-activated protein kinase and some members of the signal transducers - and activators of transcription family. In addition to kidney and liver, EPO mRNA - has been detected in other tissues; accordingly EPO receptor has been identified - in several type of cells and recent reports have suggested new roles for EPO in - non-haematopoietic tissues with a robust evidence for neuroprotective and - cardioprotective activity. In different animal models, in vitro, in isolated - perfused heart and in vivo, recombinant human erythropoietin protects heart from - ischemia reperfusion injury and reduces myocardial damage. EPO tissue protective - activity can be separated from erythropoietic activity. Molecules owing the first - property but not the second one have been described. In patients with acute - myocardial infarction serum EPO level correlates inversely with infarct size. - Acute coronary syndrome, extracorporeal circulation and percutaneous coronary - intervention are potential fields of application for tissue protective EPO - activity to reduce myocardial damage, increase cardiac function ad improve - outcome. -FAU - Mocini, D -AU - Mocini D -AD - Division of Cardiology, Cardiovascular Department, S. Filippo Neri Hospital, - Rome, Italy. david.mocini@fastwebnet.it -FAU - Leone, T -AU - Leone T -FAU - Tubaro, M -AU - Tubaro M -FAU - Santini, M -AU - Santini M -FAU - Penco, M -AU - Penco M -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Receptors, Erythropoietin) -RN - 0 (Recombinant Proteins) -RN - 11096-26-7 (Erythropoietin) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*drug therapy/metabolism -MH - Erythropoietin/blood/chemistry/genetics/*metabolism/pharmacology/*therapeutic use -MH - Humans -MH - Receptors, Erythropoietin/metabolism -MH - Recombinant Proteins -RF - 215 -EDAT- 2007/09/28 09:00 -MHDA- 2007/12/06 09:00 -CRDT- 2007/09/28 09:00 -PHST- 2007/09/28 09:00 [pubmed] -PHST- 2007/12/06 09:00 [medline] -PHST- 2007/09/28 09:00 [entrez] -AID - 10.2174/092986707781696627 [doi] -PST - ppublish -SO - Curr Med Chem. 2007;14(21):2278-87. doi: 10.2174/092986707781696627. - -PMID- 16798260 -OWN - NLM -STAT- MEDLINE -DCOM- 20060814 -LR - 20060626 -IS - 1552-6259 (Electronic) -IS - 0003-4975 (Linking) -VI - 82 -IP - 1 -DP - 2006 Jul -TI - Current strategies in the management of atrial fibrillation. -PG - 357-64 -AB - Treatment of atrial fibrillation (AF) has been undergoing significant changes - recently. This is due partly to different mechanisms proposed for persistent and - permanent AF and partly due to the introduction of energy-based techniques, - providing less invasive procedures. This article aims to review the mechanisms of - AF leading to the changes in clinical practice and to review the results of - surgery, energy-based, and percutaneous techniques. It is difficult to compare - and contrast the results of reported series in the literature due to different - definitions of AF; freedom from and recurrence of it. Furthermore, in most series - it is difficult to distinguish results of surgery for lone AF and AF associated - with valvular heart disease and coronary artery disease. -FAU - Jahangiri, Marjan -AU - Jahangiri M -AD - Department of Cardiac Surgery, St. George's Hospital Medical School, London, - United Kingdom. marjan.jahangiri@stgeorges.nhs.uk -FAU - Weir, Graeme -AU - Weir G -FAU - Mandal, Kaushik -AU - Mandal K -FAU - Savelieva, Irina -AU - Savelieva I -FAU - Camm, John -AU - Camm J -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Ann Thorac Surg -JT - The Annals of thoracic surgery -JID - 15030100R -SB - IM -MH - Atrial Fibrillation/drug - therapy/epidemiology/etiology/physiopathology/*surgery/therapy -MH - Case Management -MH - Catheter Ablation/methods -MH - Combined Modality Therapy -MH - Cryosurgery/methods -MH - Electric Countershock -MH - Endocardium/surgery -MH - Ganglia, Autonomic/surgery -MH - Heart Conduction System/physiopathology -MH - Heart Valve Diseases/complications -MH - Humans -MH - Microwaves/therapeutic use -MH - Models, Cardiovascular -MH - Pacemaker, Artificial -MH - Pericardium/surgery -MH - Postoperative Complications/epidemiology/etiology -MH - Pulmonary Veins/innervation/surgery -RF - 91 -EDAT- 2006/06/27 09:00 -MHDA- 2006/08/15 09:00 -CRDT- 2006/06/27 09:00 -PHST- 2005/08/04 00:00 [received] -PHST- 2005/11/10 00:00 [revised] -PHST- 2005/11/22 00:00 [accepted] -PHST- 2006/06/27 09:00 [pubmed] -PHST- 2006/08/15 09:00 [medline] -PHST- 2006/06/27 09:00 [entrez] -AID - S0003-4975(05)02131-4 [pii] -AID - 10.1016/j.athoracsur.2005.11.035 [doi] -PST - ppublish -SO - Ann Thorac Surg. 2006 Jul;82(1):357-64. doi: 10.1016/j.athoracsur.2005.11.035. - -PMID- 21671854 -OWN - NLM -STAT- MEDLINE -DCOM- 20111025 -LR - 20190823 -IS - 1875-533X (Electronic) -IS - 0929-8673 (Linking) -VI - 18 -IP - 21 -DP - 2011 -TI - Low lymphocyte count and cardiovascular diseases. -PG - 3226-33 -AB - Inflammation plays a crucial pathophysiological role in the entire continuum of - the atherosclerotic process, from its initiation, progression, and plaque - destabilization leading ultimately to an acute coronary event. Furthermore, once - the clinical event has occurred, inflammation also influences the left - ventricular remodelling process. Under the same paradigm, there is evidence that - lymphocytes play an important role in the modulation of the inflammatory response - at every level of the atherosclerotic process. Low lymphocyte count (LLC) is a - common finding during the systemic inflammatory response, and clinical and animal - studies suggest that LCC plays a putative role in accelerated atherosclerosis. - For instance, there is recent evidence that LLC is associated with worse outcomes - in patients with heart failure, chronic ischemic heart disease and acute coronary - syndromes. Further indirect evidence supports the pathologic role of LLC related - to the fact that 1) lymphopenia--due to a decreased count of lymphocyte T - cells--normally occurs as a part of the human ageing process, and 2) increased - incidence of cardiovascular events has been reported in conditions where - lymphopenia is common, such as renal transplant recipients, human - immunodeficiency virus infection, survivors of nuclear disasters and autoimmune - diseases. The aim of the present article is to review: a) the pathophysiological - mechanisms that have been proposed for the observed association between LLC and - cardiovascular diseases (CVD), b) the available evidence regarding the diagnostic - and prognostic role attributable to LLC in patients with CVD, and; c) the - potential therapeutic implications of these findings. -FAU - Núñez, J -AU - Núñez J -AD - Servicio de Cardiología, Hospital Clínico Universitario, INCLIVA, Universitat de - Valencia, Spain. yulnunez@gmail.com -FAU - Miñana, G -AU - Miñana G -FAU - Bodí, V -AU - Bodí V -FAU - Núñez, E -AU - Núñez E -FAU - Sanchis, J -AU - Sanchis J -FAU - Husser, O -AU - Husser O -FAU - Llàcer, A -AU - Llàcer A -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*complications/*diagnosis/physiopathology -MH - Humans -MH - Immune System Diseases/complications -MH - Lymphocyte Count -MH - Lymphocytes/pathology -MH - Lymphopenia/*complications/diagnosis -MH - Prognosis -EDAT- 2011/06/16 06:00 -MHDA- 2011/10/26 06:00 -CRDT- 2011/06/16 06:00 -PHST- 2011/02/24 00:00 [received] -PHST- 2011/05/26 00:00 [accepted] -PHST- 2011/06/16 06:00 [entrez] -PHST- 2011/06/16 06:00 [pubmed] -PHST- 2011/10/26 06:00 [medline] -AID - BSP/CMC/E-Pub/2011/ 235 [pii] -AID - 10.2174/092986711796391633 [doi] -PST - ppublish -SO - Curr Med Chem. 2011;18(21):3226-33. doi: 10.2174/092986711796391633. - -PMID- 17081085 -OWN - NLM -STAT- MEDLINE -DCOM- 20061121 -LR - 20141120 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Linking) -VI - 4 -IP - 5 -DP - 2006 Sep -TI - Use of the ACE inhibitor zofenopril in the treatment of ischemic heart disease. -PG - 631-47 -AB - Zofenopril, an inhibitor of the angiotensin-converting enzyme (ACE), has recently - been widely introduced into the pharmaceutical market. Its clinical safety and - efficacy has been demonstrated in patients with hypertension and in patients with - acute myocardial infarction (AMI). The Survival of Myocardial Infarction - Long-term Evaluation (SMILE) project provided valuable information regarding the - safety of early onset ACE inhibition with zofenopril after AMI and a greater - perception of the early and late benefits. The SMILE-I study demonstrated that - most benefits of ACE inhibition may be obtained early after AMI and persist after - discontinuation of treatment. The SMILE-II study demonstrated that early - zofenopril treatment (initiated <12 h) is safe and associated with a low rate of - severe hypotension in thrombolyzed patients with acute myocardial infarction when - administered in accordance with an adequate dose-titration scheme. Many other - studies of clinical ACE-inhibitors (ACEIs) over the last 30 years have provided - us with information in order to understand the effects of ACEIs and have - demonstrated that patients benefit from ACEI treatment at different stages of the - pathophysiological continuum of cardiovascular diseases. The current guidelines - recommend that ACEIs should be used for routine secondary prevention in all - patients with coronary artery disease and should be considered for all other - patients with coronary or other vascular disease unless contraindicated. -FAU - Buikema, Hendrik -AU - Buikema H -AD - University of Groningen, Department of Clinical Pharmacology, University Medical - Center Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands. - j.h.Buikema@med.umcg.nl -LA - eng -PT - Historical Article -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Antioxidants) -RN - 0 (Cardiotonic Agents) -RN - 290ZY759PI (zofenopril) -RN - 9G64RSX1XD (Captopril) -SB - IM -MH - Angiotensin-Converting Enzyme Inhibitors/history/*therapeutic use -MH - Antioxidants/therapeutic use -MH - Captopril/*analogs & derivatives/therapeutic use -MH - Cardiac Output, Low/drug therapy -MH - Cardiotonic Agents/therapeutic use -MH - Chronic Disease -MH - History, 19th Century -MH - History, 20th Century -MH - Humans -MH - Myocardial Infarction/drug therapy -MH - Myocardial Ischemia/*drug therapy -RF - 108 -EDAT- 2006/11/04 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/11/04 09:00 -PHST- 2006/11/04 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/11/04 09:00 [entrez] -AID - 10.1586/14779072.4.5.631 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2006 Sep;4(5):631-47. doi: 10.1586/14779072.4.5.631. - -PMID- 21150380 -OWN - NLM -STAT- MEDLINE -DCOM- 20110314 -LR - 20161125 -IS - 2331-2637 (Electronic) -IS - 1074-7931 (Linking) -VI - 16 -IP - 6 -DP - 2010 Nov -TI - Obstructive sleep apnea, stroke, and cardiovascular diseases. -PG - 329-39 -LID - 10.1097/NRL.0b013e3181f097cb [doi] -AB - BACKGROUND: Obstructive sleep apnea (OSA) is gaining recognition as a - cardiovascular and cerebrovascular risk factor. Sleep apnea is now implicated in - the etiopathogenesis of stroke, coronary artery disease, hypertension, and - congestive heart failure. REVIEW SUMMARY: OSA exerts its negative cardiovascular - consequences through its unique pattern of intermittent hypoxia and arousals. The - putative mechanisms involved in the pathogenesis of cardiovascular disease in OSA - include fibrinolytic imbalance, endothelial dysfunction, oxidative stress, and - inflammation. This study discusses the known cellular and molecular processes - that promote atherogenesis and vascular dysfunction in patients with OSA, and - their implications for cardiovascular disease and prevention in that patient - population. CONCLUSION: Neurologists should familiarize themselves with the - symptoms and signs of OSA and the pathophysiology of the association between - untreated OSA and cardiovascular disease, including stroke. OSA should be ruled - out in patients with cardiovascular disease and be regarded as an important - modifiable risk factor. Knowledge of this association is of prime public health - importance and can result in primary and secondary prevention of cardiovascular - events. This study will also help neurologists in providing patient education and - treatment. -FAU - Bagai, Kanika -AU - Bagai K -AD - Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, - USA. kanika.bagai@vanderbilt.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Neurologist -JT - The neurologist -JID - 9503763 -SB - IM -MH - Animals -MH - Arrhythmias, Cardiac/physiopathology -MH - Cardiovascular Diseases/*etiology/physiopathology -MH - Continuous Positive Airway Pressure -MH - Endothelium/physiopathology -MH - Heart Failure/physiopathology -MH - Humans -MH - Hypertension/etiology/physiopathology -MH - Hypoxia/complications -MH - Inflammation/metabolism -MH - Insulin Resistance -MH - Oxidative Stress -MH - Risk Factors -MH - Sleep Apnea, Obstructive/*complications/epidemiology/physiopathology/therapy -MH - Stroke/*etiology/physiopathology -EDAT- 2010/12/15 06:00 -MHDA- 2011/03/15 06:00 -CRDT- 2010/12/15 06:00 -PHST- 2010/12/15 06:00 [entrez] -PHST- 2010/12/15 06:00 [pubmed] -PHST- 2011/03/15 06:00 [medline] -AID - 00127893-201011000-00001 [pii] -AID - 10.1097/NRL.0b013e3181f097cb [doi] -PST - ppublish -SO - Neurologist. 2010 Nov;16(6):329-39. doi: 10.1097/NRL.0b013e3181f097cb. - -PMID- 24145591 -OWN - NLM -STAT- MEDLINE -DCOM- 20140710 -LR - 20161125 -IS - 2154-8331 (Print) -IS - 2154-8331 (Linking) -VI - 41 -IP - 4 -DP - 2013 Oct-Nov -TI - A review of the pathophysiology, diagnosis, and treatment of aortic valve - stenosis in elderly patients. -PG - 66-77 -LID - 10.3810/hp.2013.10.1082 [doi] -AB - Elderly patients experiencing valvular aortic stenosis (AS) show an increased - prevalence of coronary risk factors, coronary artery disease, and other - atherosclerotic vascular diseases. Angina pectoris, syncope or near syncope, and - congestive heart failure are the 3 classic manifestations of severe AS in - patients. Prolonged duration and late peaking of an aortic systolic ejection - murmur best differentiate severe AS from mild AS upon physical examination of the - patient. Doppler echocardiography is used to diagnose the severity of patient AS. - In the article, indications for aortic valve replacement (AVR) in patients, the - use of warfarin after AVR in patients with mechanical prostheses, and the use of - aspirin or warfarin after AVR in patients with bioprosthesis are discussed. - Transcatheter aortic valvular replacement should be performed in non-operable - patients with symptomatic severe AS to improve their survival and quality of life - rather than using regular medical management of the condition. -FAU - Aronow, Wilbert S -AU - Aronow WS -AD - Cardiology Division, Department of Medicine, Westchester Medical Center/New York - Medical College, Valhalla, New York. wsaronow@aol.com. -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Hosp Pract (1995) -JT - Hospital practice (1995) -JID - 101268948 -RN - 5Q7ZVV76EI (Warfarin) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Adult -MH - Aged -MH - Aged, 80 and over -MH - Aortic Valve/diagnostic imaging -MH - Aortic Valve Stenosis/*diagnosis/*drug - therapy/epidemiology/mortality/psychology/surgery -MH - Aspirin/*therapeutic use -MH - Echocardiography, Doppler -MH - Female -MH - Follow-Up Studies -MH - Heart Valve Prosthesis Implantation -MH - Humans -MH - Incidence -MH - Male -MH - Middle Aged -MH - Quality of Life -MH - Radiography -MH - Retrospective Studies -MH - Risk Factors -MH - Survival Analysis -MH - Treatment Outcome -MH - Warfarin/*therapeutic use -EDAT- 2013/10/23 06:00 -MHDA- 2014/07/11 06:00 -CRDT- 2013/10/23 06:00 -PHST- 2013/10/23 06:00 [entrez] -PHST- 2013/10/23 06:00 [pubmed] -PHST- 2014/07/11 06:00 [medline] -AID - 10.3810/hp.2013.10.1082 [doi] -PST - ppublish -SO - Hosp Pract (1995). 2013 Oct-Nov;41(4):66-77. doi: 10.3810/hp.2013.10.1082. - -PMID- 21256163 -OWN - NLM -STAT- MEDLINE -DCOM- 20110805 -LR - 20250529 -IS - 0006-3002 (Print) -IS - 0006-3002 (Linking) -VI - 1813 -IP - 7 -DP - 2011 Jul -TI - Mitochondrial dysfunction in diabetic cardiomyopathy. -PG - 1351-9 -LID - 10.1016/j.bbamcr.2011.01.014 [doi] -AB - Cardiovascular disease is common in patients with diabetes and is a significant - contributor to the high mortality rates associated with diabetes. Heart failure - is common in diabetic patients, even in the absence of coronary artery disease or - hypertension, an entity known as diabetic cardiomyopathy. Evidence indicates that - myocardial metabolism is altered in diabetes, which likely contributes to - contractile dysfunction and ventricular failure. The mitochondria are the center - of metabolism, and recent data suggests that mitochondrial dysfunction may play a - critical role in the pathogenesis of diabetic cardiomyopathy. This review - summarizes many of the potential mechanisms that lead to mitochondrial - dysfunction in the diabetic heart. This article is part of a Special Issue - entitled: Mitochondria and Cardioprotection. -CI - Copyright © 2010 Elsevier B.V. All rights reserved. -FAU - Duncan, Jennifer G -AU - Duncan JG -AD - Department of Pediatrics, Washington University School of Medicine, St. Louis, - MO, USA. duncan_j@wustl.edu -LA - eng -GR - P30 DK056341/DK/NIDDK NIH HHS/United States -GR - HD047349/HD/NICHD NIH HHS/United States -GR - K12 HD047349/HD/NICHD NIH HHS/United States -GR - HL084093/HL/NHLBI NIH HHS/United States -GR - K08 HL084093/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20110120 -PL - Netherlands -TA - Biochim Biophys Acta -JT - Biochimica et biophysica acta -JID - 0217513 -RN - 0 (Fatty Acids) -RN - 0 (Triglycerides) -SB - IM -MH - Animals -MH - Diabetes Mellitus/*metabolism -MH - Diabetic Cardiomyopathies/*metabolism -MH - *Energy Metabolism -MH - Fatty Acids/blood -MH - Heart/physiopathology -MH - Heart Failure/*metabolism -MH - Humans -MH - Mitochondria, Heart/*metabolism -MH - Myocardium/*metabolism -MH - Oxidative Stress -MH - Triglycerides/blood -PMC - PMC3149859 -MID - NIHMS276677 -EDAT- 2011/01/25 06:00 -MHDA- 2011/08/06 06:00 -PMCR- 2012/07/01 -CRDT- 2011/01/25 06:00 -PHST- 2010/06/16 00:00 [received] -PHST- 2010/12/21 00:00 [revised] -PHST- 2011/01/11 00:00 [accepted] -PHST- 2011/01/25 06:00 [entrez] -PHST- 2011/01/25 06:00 [pubmed] -PHST- 2011/08/06 06:00 [medline] -PHST- 2012/07/01 00:00 [pmc-release] -AID - S0167-4889(11)00022-X [pii] -AID - 10.1016/j.bbamcr.2011.01.014 [doi] -PST - ppublish -SO - Biochim Biophys Acta. 2011 Jul;1813(7):1351-9. doi: 10.1016/j.bbamcr.2011.01.014. - Epub 2011 Jan 20. - -PMID- 16331093 -OWN - NLM -STAT- MEDLINE -DCOM- 20060302 -LR - 20190823 -IS - 0263-6352 (Print) -IS - 0263-6352 (Linking) -VI - 24 -IP - 1 -DP - 2006 Jan -TI - Blockade of the renin-angiotensin-aldosterone system: a key therapeutic strategy - to reduce renal and cardiovascular events in patients with diabetes. -PG - 11-25 -AB - Diabetes (particularly type 2 diabetes) represents a global health problem of - epidemic proportions. Individuals with diabetes are not only more likely to - develop hypertension, dyslipidemia, and obesity, but are also at a significantly - higher risk for coronary heart disease, peripheral vascular disease, and stroke. - Angiotensin II plays a key pathophysiological role in the progression of diabetic - renal disease, and blockade of the renin-angiotensin system with - angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II antagonists has - therefore become an important therapeutic strategy to reduce renal and - cardiovascular events in patients with diabetes. Several studies have - demonstrated the effects of angiotensin II antagonists on the reduction of - albuminuria and the progression of renal disease from microalbuminuria to - macroalbuminuria. More importantly, several endpoint trials have shown that the - antiproteinuric effects of losartan and irbesartan translate into cardiovascular - and renoprotective benefits beyond blood pressure lowering, thereby delaying the - need for dialysis or kidney transplantation by several years. These and other - studies indicate that angiotensin II antagonists not only improve survival and - quality of life of patients with diabetic nephropathy, but also have the - potential to reduce the substantial healthcare burden associated with managing - these patients. ACEi also appear to exert similar beneficial effects in diabetic - patients, but whether clinically significant differences in renoprotection or - mortality exist between angiotensin II antagonists and ACEi in patients with type - 2 diabetes remains to be fully investigated in appropriate head-to-head studies. -FAU - Burnier, Michel -AU - Burnier M -AD - Service de Néphrologie, Department of Medicine, Lausanne Switzerland. - michael.burnier@chuv.hospvd.ch -FAU - Zanchi, Anne -AU - Zanchi A -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Netherlands -TA - J Hypertens -JT - Journal of hypertension -JID - 8306882 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Biphenyl Compounds) -RN - 0 (Tetrazoles) -RN - J0E2756Z7N (Irbesartan) -RN - JMS50MPO89 (Losartan) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/economics/pharmacology/*therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/economics/pharmacology/*therapeutic use -MH - Biphenyl Compounds/economics/pharmacology/therapeutic use -MH - Clinical Trials as Topic -MH - Cost-Benefit Analysis -MH - Diabetes Mellitus, Type 2/*complications/physiopathology/prevention & control -MH - Diabetic Angiopathies/mortality/physiopathology/*prevention & control -MH - Diabetic Nephropathies/mortality/physiopathology/*prevention & control -MH - Diabetic Neuropathies/mortality/physiopathology/*prevention & control -MH - Disease Progression -MH - Humans -MH - Hypertension/drug therapy/physiopathology -MH - Irbesartan -MH - Losartan/economics/pharmacology/therapeutic use -MH - Renin-Angiotensin System/*drug effects/physiology -MH - Tetrazoles/economics/pharmacology/therapeutic use -RF - 183 -EDAT- 2005/12/07 09:00 -MHDA- 2006/03/03 09:00 -CRDT- 2005/12/07 09:00 -PHST- 2005/12/07 09:00 [pubmed] -PHST- 2006/03/03 09:00 [medline] -PHST- 2005/12/07 09:00 [entrez] -AID - 00004872-200601000-00003 [pii] -AID - 10.1097/01.hjh.0000191244.91314.9d [doi] -PST - ppublish -SO - J Hypertens. 2006 Jan;24(1):11-25. doi: 10.1097/01.hjh.0000191244.91314.9d. - -PMID- 19441677 -OWN - NLM -STAT- MEDLINE -DCOM- 20090618 -LR - 20181201 -IS - 0033-2240 (Print) -IS - 0033-2240 (Linking) -VI - 65 -IP - 12 -DP - 2008 -TI - [New approach to interventional cardiology treatment with personalized medicine]. -PG - 850-7 -AB - Structural and functional genomics enable identification of genes involved in - incorrect response or resistance to treatment. These techniques improve - prevention and specialized treatment in patients with cardiovascular disease - (CVD), especially after acute myocardial infarction. AIM: To summarize and - present the most recent information about individual genetic factors involved in - treatment failure after acute coronary syndromes (ACS) and describe new frontiers - in development of personalized medicine during every day practice. The molecular - basis and prediction value of these studies confirm their importance for the - future of invasive cardiology. METHOD: Based on Medline database, a search of - recent studies and trials published between 2000 and 2007 concerning personalized - medicine in ACS treatment was performed. RESULTS: Analyzed literature indicate - possibilities of improving effective treatment and prevention of CVD based on - study of structure of genome, epidemiological factors and implementation of these - findings into everyday clinical practice. Clinical studies concerning ACE - polymorphism, revealed significant relationship between the DD allele in ACE - genome and increased mortality or need for heart transplantation. The risk was - significantly higher in patients without beta-blocker treatment. Clopidogrel - treatment is proven to be ineffective in 10-30% of patients. The impaired - activity of CYP3A4 enzyme, changing in individuals is considered to be the reason - for inadequate response to clopidogrel treatment. Use of the enzyme activators - such as rifampicine improves the outcomes. New generations of antiplatelet drugs - such as AZD6140, which do not need to covert to an active form are under - investigation. Total resistance to aspirin treatment was proven in 5.5-9.5% of - patients, but 23.8% presented suboptimal response to therapy. -FAU - Podolec, Jakub -AU - Podolec J -AD - Zakład Hemodynamiki i Angiokardiografii, Instytut Kardiologii Uniwersytet - Jagielloński Collegium Medium, Kraków. jakubpodolec@poczta.onet.pl -FAU - Gajos, Grzegorz -AU - Gajos G -FAU - Budziaszek, Łukasz -AU - Budziaszek Ł -FAU - Czaniecka, Małgorzata -AU - Czaniecka M -FAU - Kleczkoska, Alicja -AU - Kleczkoska A -FAU - Zmudka', Krzysztof -AU - Zmudka' K -LA - pol -PT - Journal Article -PT - Review -TT - Personalized medicine, a przyszłość kardiologii interwencyjnej. -PL - Poland -TA - Przegl Lek -JT - Przeglad lekarski -JID - 19840720R -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Acute Coronary Syndrome/*genetics/*prevention & control -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Aspirin/therapeutic use -MH - Clopidogrel -MH - Drug Resistance/*genetics -MH - Hematologic Diseases -MH - Humans -MH - Myocardial Infarction/genetics/prevention & control -MH - Personal Health Services/*methods -MH - Ticlopidine/analogs & derivatives/therapeutic use -MH - Treatment Failure -RF - 46 -EDAT- 2008/01/01 00:00 -MHDA- 2009/06/19 09:00 -CRDT- 2009/05/16 09:00 -PHST- 2009/05/16 09:00 [entrez] -PHST- 2008/01/01 00:00 [pubmed] -PHST- 2009/06/19 09:00 [medline] -PST - ppublish -SO - Przegl Lek. 2008;65(12):850-7. - -PMID- 19726805 -OWN - NLM -STAT- MEDLINE -DCOM- 20100112 -LR - 20220408 -IS - 1754-8411 (Electronic) -IS - 1754-8403 (Linking) -VI - 2 -IP - 9-10 -DP - 2009 Sep-Oct -TI - Rodent models of diabetic cardiomyopathy. -PG - 454-66 -LID - 10.1242/dmm.001941 [doi] -AB - Diabetic cardiomyopathy increases the risk of heart failure in individuals with - diabetes, independently of co-existing coronary artery disease and hypertension. - The underlying mechanisms for this cardiac complication are incompletely - understood. Research on rodent models of type 1 and type 2 diabetes, and the use - of genetic engineering techniques in mice, have greatly advanced our - understanding of the molecular mechanisms responsible for human diabetic - cardiomyopathy. The adaptation of experimental techniques for the investigation - of cardiac physiology in mice now allows comprehensive characterization of these - models. The focus of the present review will be to discuss selected rodent models - that have proven to be useful in studying the underlying mechanisms of human - diabetic cardiomyopathy, and to provide an overview of the characteristics of - these models for the growing number of investigators who seek to understand the - pathology of diabetes-related heart disease. -FAU - Bugger, Heiko -AU - Bugger H -AD - Division of Endocrinology, Metabolism and Diabetes, and Program in Molecular - Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA. -FAU - Abel, E Dale -AU - Abel ED -LA - eng -GR - R01 DK092065/DK/NIDDK NIH HHS/United States -GR - R01 HL070070/HL/NHLBI NIH HHS/United States -GR - U01 HL087947/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Dis Model Mech -JT - Disease models & mechanisms -JID - 101483332 -SB - IM -MH - Animals -MH - Cardiomyopathies/*complications -MH - Diabetes Complications/*complications -MH - *Disease Models, Animal -MH - Genetic Engineering -MH - Humans -MH - Rodentia/*genetics -RF - 150 -EDAT- 2009/09/04 06:00 -MHDA- 2010/01/13 06:00 -CRDT- 2009/09/04 06:00 -PHST- 2009/09/04 06:00 [entrez] -PHST- 2009/09/04 06:00 [pubmed] -PHST- 2010/01/13 06:00 [medline] -AID - 2/9-10/454 [pii] -AID - 10.1242/dmm.001941 [doi] -PST - ppublish -SO - Dis Model Mech. 2009 Sep-Oct;2(9-10):454-66. doi: 10.1242/dmm.001941. - -PMID- 24480445 -OWN - NLM -STAT- MEDLINE -DCOM- 20140415 -LR - 20220317 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 30 -IP - 3 -DP - 2014 Mar -TI - The 2013 Canadian Cardiovascular Society Heart Failure Management Guidelines - Update: focus on rehabilitation and exercise and surgical coronary - revascularization. -PG - 249-63 -LID - S0828-282X(13)01576-6 [pii] -LID - 10.1016/j.cjca.2013.10.010 [doi] -AB - The 2013 Canadian Cardiovascular Society Heart Failure Management Guidelines - Update provides focused discussions on the management recommendations on 2 - topics: (1) exercise and rehabilitation; and (2) surgical coronary - revascularization in patients with heart failure. First, all patients with stable - New York Heart Association class I-III symptoms should be considered for - enrollment in a tailored exercise training program, to improve exercise tolerance - and quality of life. Second, selected patients with suitable coronary anatomy - should be considered for bypass graft surgery. As in previous updates, the topics - were chosen in response to stakeholder feedback. The 2013 Update also includes - recommendations, values and preferences, and practical tips to assist the - clinicians and health care workers manage their patients with heart failure. -CI - Copyright © 2014 Canadian Cardiovascular Society. Published by Elsevier Inc. All - rights reserved. -CN - Canadian Cardiovascular Society Heart Failure Management Primary Panel -FAU - Moe, Gordon W -AU - Moe GW -AD - St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. - Electronic address: moeg@smh.ca. -FAU - Ezekowitz, Justin A -AU - Ezekowitz JA -AD - University of Alberta, Edmonton, Alberta, Canada. -FAU - O'Meara, Eileen -AU - O'Meara E -AD - Institut de Cardiologie de Montréal, Montreal, Québec, Canada. -FAU - Howlett, Jonathan G -AU - Howlett JG -AD - University of Calgary, Calgary, Alberta, Canada. -FAU - Fremes, Steve E -AU - Fremes SE -AD - Sunnybrook Health Science Centre, Toronto, Ontario, Canada. -FAU - Al-Hesayen, Abdul -AU - Al-Hesayen A -AD - St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. -FAU - Heckman, George A -AU - Heckman GA -AD - University of Waterloo, Waterloo, Ontario, Canada. -FAU - Ducharme, Anique -AU - Ducharme A -AD - Institut de Cardiologie de Montréal, Montreal, Québec, Canada. -FAU - Estrella-Holder, Estrellita -AU - Estrella-Holder E -AD - Cardiac Sciences Program, St Boniface General Hospital, Winnipeg, Manitoba, - Canada. -FAU - Grzeslo, Adam -AU - Grzeslo A -AD - Joseph Brant Memorial Hospital, Burlington, Ontario, Canada; Hamilton Health - Sciences, McMaster University, Hamilton, Ontario, Canada. -FAU - Harkness, Karen -AU - Harkness K -AD - Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada. -FAU - Lepage, Serge -AU - Lepage S -AD - Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada. -FAU - McDonald, Michael -AU - McDonald M -AD - University Health Network, University of Toronto, Toronto, Ontario, Canada. -FAU - McKelvie, Robert S -AU - McKelvie RS -AD - Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada. -FAU - Nigam, Anil -AU - Nigam A -AD - Institut de Cardiologie de Montréal, Montreal, Québec, Canada. -FAU - Rajda, Miroslaw -AU - Rajda M -AD - QE II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia, Canada. -FAU - Rao, Vivek -AU - Rao V -AD - University Health Network, University of Toronto, Toronto, Ontario, Canada. -FAU - Swiggum, Elizabeth -AU - Swiggum E -AD - Royal Jubilee Hospital, Victoria, British Columbia, Canada. -FAU - Virani, Sean -AU - Virani S -AD - University of British Columbia, Vancouver, British Columbia, Canada. -FAU - Van Le, Vy -AU - Van Le V -AD - Centre Hospitalier Universitaire de l'Université de Montréal, Québec, Canada. -FAU - Zieroth, Shelley -AU - Zieroth S -AD - Cardiac Sciences Program, St Boniface General Hospital, Winnipeg, Manitoba, - Canada. -CN - Canadian Cardiovascular Society Heart Failure Management Secondary Panel -FAU - Arnold, J Malcolm O -AU - Arnold JM -AD - University of Western Ontario, London, Ontario, Canada. -FAU - Ashton, Tom -AU - Ashton T -AD - Penticton, British Columbia, Canada. -FAU - D'Astous, Michel -AU - D'Astous M -AD - Université de Moncton, Moncton, New Brunswick, Canada. -FAU - Dorian, Paul -AU - Dorian P -AD - St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. -FAU - Giannetti, Nadia -AU - Giannetti N -AD - McGill University, Montreal, Québec, Canada. -FAU - Haddad, Haissam -AU - Haddad H -AD - Ottawa Heart Institute, Ottawa, Ontario, Canada. -FAU - Isaac, Debra L -AU - Isaac DL -AD - University of Calgary, Calgary, Alberta, Canada. -FAU - Kouz, Simon -AU - Kouz S -AD - Centre Hospitalier Régional de Lanaudière, Joliette, and Université Laval, - Québec, Canada. -FAU - Leblanc, Marie-Hélène -AU - Leblanc MH -AD - Hôpital Laval, Sainte-Foy, Québec, Canada. -FAU - Liu, Peter -AU - Liu P -AD - Ottawa Heart Institute, Ottawa, Ontario, Canada. -FAU - Ross, Heather J -AU - Ross HJ -AD - University Health Network, University of Toronto, Toronto, Ontario, Canada. -FAU - Sussex, Bruce -AU - Sussex B -AD - Health Sciences Centre, St John's, Newfoundland, Canada. -FAU - White, Michel -AU - White M -AD - Institut de Cardiologie de Montréal, Montreal, Québec, Canada. -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131019 -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Canada -MH - *Cardiology -MH - Disease Management -MH - Exercise Therapy/*statistics & numerical data -MH - Heart Failure/*therapy -MH - Humans -MH - Myocardial Revascularization/*standards -MH - *Practice Guidelines as Topic -MH - *Societies, Medical -FIR - Moe, Gordon W -IR - Moe GW -FIR - Ezekowitz, Justin A -IR - Ezekowitz JA -FIR - O'Meara, Eileen -IR - O'Meara E -FIR - Howlett, Jonathan G -IR - Howlett JG -FIR - Fremes, Steve E -IR - Fremes SE -FIR - Al-Hesayen, Abdul -IR - Al-Hesayen A -FIR - Heckman, George A -IR - Heckman GA -FIR - Ducharme, Anique -IR - Ducharme A -FIR - Estrella-Holder, Estrellita -IR - Estrella-Holder E -FIR - Grzeslo, Adam -IR - Grzeslo A -FIR - Harkness, Karen -IR - Harkness K -FIR - Lepage, Serge -IR - Lepage S -FIR - McDonald, Michael -IR - McDonald M -FIR - McKelvie, Robert S -IR - McKelvie RS -FIR - Nigam, Anil -IR - Nigam A -FIR - Rajda, Miroslaw -IR - Rajda M -FIR - Rao, Vivek -IR - Rao V -FIR - Swiggum, Elizabeth -IR - Swiggum E -FIR - Virani, Sean -IR - Virani S -FIR - Van Le, Vy -IR - Van Le V -FIR - Zieroth, Shelley -IR - Zieroth S -FIR - Arnold, J Malcolm O -IR - Arnold J -FIR - Ashton, Tom -IR - Ashton T -FIR - D'Astous, Michel -IR - D'Astous M -FIR - Dorian, Paul -IR - Dorian P -FIR - Giannetti, Nadia -IR - Giannetti N -FIR - Haddad, Haissam -IR - Haddad H -FIR - Isaac, Debra L -IR - Isaac DL -FIR - Kouz, Simon -IR - Kouz S -FIR - Marie-Hélène, Leblanc -IR - Marie-Hélène L -FIR - Liu, Peter -IR - Liu P -FIR - Ross, Heather J -IR - Ross HJ -FIR - Sussex, Bruce -IR - Sussex B -FIR - White, Michel -IR - White M -EDAT- 2014/02/01 06:00 -MHDA- 2014/04/16 06:00 -CRDT- 2014/02/01 06:00 -PHST- 2013/09/24 00:00 [received] -PHST- 2013/10/09 00:00 [revised] -PHST- 2013/10/09 00:00 [accepted] -PHST- 2014/02/01 06:00 [entrez] -PHST- 2014/02/01 06:00 [pubmed] -PHST- 2014/04/16 06:00 [medline] -AID - S0828-282X(13)01576-6 [pii] -AID - 10.1016/j.cjca.2013.10.010 [doi] -PST - ppublish -SO - Can J Cardiol. 2014 Mar;30(3):249-63. doi: 10.1016/j.cjca.2013.10.010. Epub 2013 - Oct 19. - -PMID- 17662491 -OWN - NLM -STAT- MEDLINE -DCOM- 20080507 -LR - 20181201 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 125 -IP - 3 -DP - 2008 Apr 25 -TI - The Aristotelian account of "heart and veins". -PG - 304-10 -AB - The exploration of the cardiovascular (CV) system has a history of at least five - millennia. The model of the heart and veins represented by Aristotle (384-322 - B.C.) is one of the earliest and accurate descriptions of the CV system. With his - own specific metaphysical approach, Aristotle discussed why there might be a - vascular tree composed of two vessels and also why these vessels must extend - throughout the entire body. Herein, the authors present a history of the original - account of the CV system based on the studies and teachings of Aristotle who made - detailed observations and experimented upon animals and human corpses to explore - the anatomy of the heart and vessels and thus provided the basis for modern CV - medicine. The Aristotelian CV model consisted of two related but slightly - dissimilar passages based on experimentation and tradition, which could be - perceived as the morphology and metaphysical accounts of physiology, - respectively. Restricted by his own methodology of dissecting dead animals, - Aristotle was the first to describe the anatomy of the heart and blood vessels. A - thorough reading of his Historia Animalium showed that he was able to - morphologically delineate the right atrium in addition to three distinct heart - cavities corresponding to the left atrium and right and left ventricles. The - authors conclude that when interpreting Aristotelian doctrine, the methodology - and terminology should be taken into account in order to prevent potential - misconceptions. It is the early work of such scientists as Aristotle on which we - base our current understanding of the CV system. -FAU - Shoja, Mohammadali M -AU - Shoja MM -AD - Tuberculosis and Lung Disease Research Center, Tabriz Medical University, Tabriz, - Iran. -FAU - Tubbs, R Shane -AU - Tubbs RS -FAU - Loukas, Marios -AU - Loukas M -FAU - Ardalan, Mohammad R -AU - Ardalan MR -LA - eng -PT - Biography -PT - Historical Article -PT - Journal Article -PT - Portrait -PT - Review -DEP - 20070726 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -SB - IM -MH - Anatomy/*history -MH - Animals -MH - Blood Circulation -MH - Coronary Vessels/anatomy & histology -MH - Greece, Ancient -MH - Heart/anatomy & histology -MH - History, Ancient -MH - Humans -MH - Textbooks as Topic/history -RF - 13 -EDAT- 2007/07/31 09:00 -MHDA- 2008/05/08 09:00 -CRDT- 2007/07/31 09:00 -PHST- 2007/05/29 00:00 [received] -PHST- 2007/07/01 00:00 [accepted] -PHST- 2007/07/31 09:00 [pubmed] -PHST- 2008/05/08 09:00 [medline] -PHST- 2007/07/31 09:00 [entrez] -AID - S0167-5273(07)01065-0 [pii] -AID - 10.1016/j.ijcard.2007.07.001 [doi] -PST - ppublish -SO - Int J Cardiol. 2008 Apr 25;125(3):304-10. doi: 10.1016/j.ijcard.2007.07.001. Epub - 2007 Jul 26. - -PMID- 18356635 -OWN - NLM -STAT- MEDLINE -DCOM- 20080605 -LR - 20151119 -IS - 1536-3686 (Electronic) -IS - 1075-2765 (Linking) -VI - 15 -IP - 2 -DP - 2008 Mar-Apr -TI - B-type natriuretic peptide (BNP) and proBNP: role of emerging markers to guide - therapy and determine prognosis in cardiovascular disorders. -PG - 150-6 -LID - 10.1097/MJT.0b013e31815af96f [doi] -AB - Over the last decade, one group of neurohormonal markers, including atrial - natriuretic peptide (ANP), N-terminal pro-ANP, B-type natriuretic peptide (BNP), - and N-terminal proBNP, has generated much interest in the evaluation and - management of heart failure and acute coronary syndrome. There has been so much - literature on the subject, especially concerning BNP and proBNP, that it leaves - us confused at times about what the literature has to say about these markers. In - this article, we have made an honest attempt to examine all the available - literature in relation to the impact of BNP and proBNP on cardiovascular disease - and present it to the reader in an assimilated fashion. -FAU - Godkar, Darshan -AU - Godkar D -AD - Department of Cardiology, Coney Island Hospital, Brooklyn, NY, USA. - darshangodkar@yahoo.com -FAU - Bachu, Kalyan -AU - Bachu K -FAU - Dave, Bijal -AU - Dave B -FAU - Niranjan, Selva -AU - Niranjan S -FAU - Khanna, Ashok -AU - Khanna A -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Ther -JT - American journal of therapeutics -JID - 9441347 -RN - 0 (Biomarkers) -RN - 0 (Peptide Fragments) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Biomarkers/blood -MH - Heart Diseases/*diagnosis/*drug therapy -MH - Humans -MH - Natriuretic Peptide, Brain/*blood -MH - Peptide Fragments/*blood -MH - Predictive Value of Tests -MH - Prognosis -MH - Severity of Illness Index -RF - 70 -EDAT- 2008/03/22 09:00 -MHDA- 2008/06/06 09:00 -CRDT- 2008/03/22 09:00 -PHST- 2008/03/22 09:00 [pubmed] -PHST- 2008/06/06 09:00 [medline] -PHST- 2008/03/22 09:00 [entrez] -AID - 00045391-200803000-00010 [pii] -AID - 10.1097/MJT.0b013e31815af96f [doi] -PST - ppublish -SO - Am J Ther. 2008 Mar-Apr;15(2):150-6. doi: 10.1097/MJT.0b013e31815af96f. - -PMID- 18314435 -OWN - NLM -STAT- MEDLINE -DCOM- 20080307 -LR - 20181201 -IS - 1538-3598 (Electronic) -IS - 0098-7484 (Linking) -VI - 299 -IP - 8 -DP - 2008 Feb 27 -TI - Clinical applications of blood-derived and marrow-derived stem cells for - nonmalignant diseases. -PG - 925-36 -LID - 10.1001/jama.299.8.925 [doi] -AB - CONTEXT: Stem cell therapy is rapidly developing and has generated excitement and - promise as well as confusion and at times contradictory results in the lay and - scientific literature. Many types of stem cells show great promise, but clinical - application has lagged due to ethical concerns or difficulties in harvesting or - safely and efficiently expanding sufficient quantities. In contrast, clinical - indications for blood-derived (from peripheral or umbilical cord blood) and bone - marrow-derived stem cells, which can be easily and safely harvested, are rapidly - increasing. OBJECTIVE: To summarize new, nonmalignant, nonhematologic clinical - indications for use of blood- and bone marrow-derived stem cells. EVIDENCE - ACQUISITION: Search of multiple electronic databases (MEDLINE, EMBASE, Science - Citation Index), US Food and Drug Administration [FDA] Drug Site, and National - Institutes of Health Web site to identify studies published from January 1997 to - December 2007 on use of hematopoietic stem cells (HSCs) in autoimmune, cardiac, - or vascular diseases. The search was augmented by hand searching of reference - lists in clinical trials, review articles, proceedings booklets, FDA reports, and - contact with study authors and device and pharmaceutical companies. EVIDENCE - SYNTHESIS: Of 926 reports identified, 323 were examined for feasibility and - toxicity, including those with small numbers of patients, interim or substudy - reports, and reports on multiple diseases, treatment of relapse, toxicity, - mechanism of action, or stem cell mobilization. Another 69 were evaluated for - outcomes. For autoimmune diseases, 26 reports representing 854 patients reported - treatment-related mortality of less than 1% (2/220 patients) for - nonmyeloablative, less than 2% (3/197) for dose-reduced myeloablative, and 13% - (13/100) for intense myeloablative regimens, ie, those including total body - irradiation or high-dose busulfan. While all trials performed during the - inflammatory stage of autoimmune disease suggested that transplantation of HSCs - may have a potent disease-remitting effect, remission duration remains unclear, - and no randomized trials have been published. For reports involving - cardiovascular diseases, including 17 reports involving 1002 patients with acute - myocardial infarction, 16 involving 493 patients with chronic coronary artery - disease, and 3 meta-analyses, the evidence suggests that stem cell - transplantation performed in patients with coronary artery disease may contribute - to modest improvement in cardiac function. CONCLUSIONS: Stem cells harvested from - blood or marrow, whether administered as purified HSCs or mesenchymal stem cells - or as an unmanipulated or unpurified product can, under appropriate conditions in - select patients, provide disease-ameliorating effects in some autoimmune diseases - and cardiovascular disorders. Clinical trials are needed to determine the most - appropriate cell type, dose, method, timing of delivery, and adverse effects of - adult HSCs for these and other nonmalignant disorders. -FAU - Burt, Richard K -AU - Burt RK -AD - Division of Immunotherapy, Department of Medicine, Northwestern University - Feinberg School of Medicine, Chicago, Illinois 60611, USA. rburt@northwestern.edu -FAU - Loh, Yvonne -AU - Loh Y -FAU - Pearce, William -AU - Pearce W -FAU - Beohar, Nirat -AU - Beohar N -FAU - Barr, Walter G -AU - Barr WG -FAU - Craig, Robert -AU - Craig R -FAU - Wen, Yanting -AU - Wen Y -FAU - Rapp, Jonathan A -AU - Rapp JA -FAU - Kessler, John -AU - Kessler J -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - JAMA -JT - JAMA -JID - 7501160 -SB - IM -CIN - JAMA. 2008 Jun 18;299(23):2746; author reply 2746-7. doi: - 10.1001/jama.299.23.2746-b. PMID: 18560000 -MH - Autoimmune Diseases/*therapy -MH - Heart Diseases/*therapy -MH - Hematopoietic Stem Cells -MH - Humans -MH - Mesenchymal Stem Cells -MH - *Stem Cell Transplantation -MH - Vascular Diseases/*therapy -RF - 111 -EDAT- 2008/03/04 09:00 -MHDA- 2008/03/08 09:00 -CRDT- 2008/03/04 09:00 -PHST- 2008/03/04 09:00 [pubmed] -PHST- 2008/03/08 09:00 [medline] -PHST- 2008/03/04 09:00 [entrez] -AID - 299/8/925 [pii] -AID - 10.1001/jama.299.8.925 [doi] -PST - ppublish -SO - JAMA. 2008 Feb 27;299(8):925-36. doi: 10.1001/jama.299.8.925. - -PMID- 22749884 -OWN - NLM -STAT- MEDLINE -DCOM- 20130103 -LR - 20120817 -IS - 1943-7811 (Electronic) -IS - 1525-1578 (Linking) -VI - 14 -IP - 5 -DP - 2012 Sep -TI - The genetics of cardiac disease associated with sudden cardiac death: a paper - from the 2011 William Beaumont Hospital Symposium on molecular pathology. -PG - 424-36 -LID - 10.1016/j.jmoldx.2012.04.002 [doi] -AB - Sudden cardiac death due to ventricular arrhythmia most commonly occurs in the - setting of coronary artery disease. However, a number of inherited syndromes have - now been identified that carry a significant risk of sudden cardiac death and - that are disproportionately represented in the young. Arrhythmia in such - conditions may result from genetically mediated structural heart disease (eg, - hypertrophic cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy) - or from altered function of cardiac ion channels in the absence of overt - structural disease (eg, Brugada syndrome and long QT syndrome). The past 15 years - have seen considerable progress in our understanding of the genetic underpinnings - of these disorders. With the advent of clinical genetic testing as a routine part - of clinical care, a new knowledge base is required of practicing cardiologists - and genetic testing facilities, particularly related to the rational ordering of - genetic testing and the interpretation of results. This review addresses the - latest findings in regard to the genetic causes of inherited syndromes associated - with sudden cardiac death and summarizes recently published guidelines for the - genetic testing of affected individuals and their families. -CI - Copyright © 2012 American Society for Investigative Pathology and the Association - for Molecular Pathology. Published by Elsevier Inc. All rights reserved. -FAU - Perrin, Mark J -AU - Perrin MJ -AD - Division of Cardiology, Department of Medicine, University of Ottawa Heart - Institute, Ottawa, Ontario, Canada. -FAU - Gollob, Michael H -AU - Gollob MH -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120627 -PL - United States -TA - J Mol Diagn -JT - The Journal of molecular diagnostics : JMD -JID - 100893612 -SB - IM -MH - Arrhythmogenic Right Ventricular Dysplasia/complications/genetics -MH - Brugada Syndrome/complications/genetics -MH - Cardiomyopathy, Dilated/complications/genetics -MH - Cardiomyopathy, Hypertrophic, Familial/complications/genetics -MH - Death, Sudden, Cardiac/*etiology -MH - Heart Diseases/*complications/*genetics/pathology -MH - Humans -EDAT- 2012/07/04 06:00 -MHDA- 2013/01/04 06:00 -CRDT- 2012/07/04 06:00 -PHST- 2012/02/07 00:00 [received] -PHST- 2012/04/03 00:00 [revised] -PHST- 2012/04/13 00:00 [accepted] -PHST- 2012/07/04 06:00 [entrez] -PHST- 2012/07/04 06:00 [pubmed] -PHST- 2013/01/04 06:00 [medline] -AID - S1525-1578(12)00124-9 [pii] -AID - 10.1016/j.jmoldx.2012.04.002 [doi] -PST - ppublish -SO - J Mol Diagn. 2012 Sep;14(5):424-36. doi: 10.1016/j.jmoldx.2012.04.002. Epub 2012 - Jun 27. - -PMID- 24082366 -OWN - NLM -STAT- MEDLINE -DCOM- 20140527 -LR - 20220409 -IS - 1526-6702 (Electronic) -IS - 0730-2347 (Print) -IS - 0730-2347 (Linking) -VI - 40 -IP - 4 -DP - 2013 -TI - Mitochondrial cardiomyopathy: pathophysiology, diagnosis, and management. -PG - 385-94 -AB - Mitochondrial disease is a heterogeneous group of multisystemic diseases that - develop consequent to mutations in nuclear or mitochondrial DNA. The prevalence - of inherited mitochondrial disease has been estimated to be greater than 1 in - 5,000 births; however, the diagnosis and treatment of this disease are not taught - in most adult-cardiology curricula. Because mitochondrial diseases often occur as - a syndrome with resultant multiorgan dysfunction, they might not immediately - appear to be specific to the cardiovascular system. Mitochondrial cardiomyopathy - can be described as a myocardial condition characterized by abnormal heart-muscle - structure, function, or both, secondary to genetic defects involving the - mitochondrial respiratory chain, in the absence of concomitant coronary artery - disease, hypertension, valvular disease, or congenital heart disease. The typical - cardiac manifestations of mitochondrial disease--hypertrophic and dilated - cardiomyopathy, arrhythmias, left ventricular myocardial noncompaction, and heart - failure--can worsen acutely during a metabolic crisis. The optimal management of - mitochondrial disease necessitates the involvement of a multidisciplinary team, - careful evaluations of patients, and the anticipation of iatrogenic and - noniatrogenic complications. In this review, we describe the complex - pathophysiology of mitochondrial disease and its clinical features. We focus on - current practice in the diagnosis and treatment of patients with mitochondrial - cardiomyopathy, including optimal therapeutic management and long-term - monitoring. We hope that this information will serve as a guide for practicing - cardiologists who treat patients thus affected. -FAU - Meyers, Deborah E -AU - Meyers DE -AD - Advanced Heart Failure Program (Dr. Meyers), Texas Heart Institute, Houston, - Texas 77030; Department of Internal Medicine (Dr. Basha), Hurley Medical Center, - Michigan State University, Flint, Michigan 48503; and Mitochondrial Disease - Center (Dr. Koenig), Department of Pediatrics, Division of Child & Adolescent - Neurology, The University of Texas Medical School at Houston, Houston, Texas - 77030. -FAU - Basha, Haseeb Ilias -AU - Basha HI -FAU - Koenig, Mary Kay -AU - Koenig MK -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Tex Heart Inst J -JT - Texas Heart Institute journal -JID - 8214622 -RN - 0 (DNA, Mitochondrial) -SB - IM -CIN - Tex Heart Inst J. 2013;40(5):634-5. PMID: 24391348 -CIN - Tex Heart Inst J. 2013;40(5):635-6. PMID: 24391349 -MH - Animals -MH - *Cardiomyopathies/diagnosis/genetics/metabolism/physiopathology/therapy -MH - DNA, Mitochondrial/genetics -MH - Energy Metabolism -MH - Genetic Predisposition to Disease -MH - Humans -MH - Mitochondria, Heart/metabolism -MH - Mitochondrial Diseases/diagnosis/genetics/metabolism/physiopathology/*therapy -MH - Phenotype -MH - Predictive Value of Tests -MH - Risk Factors -MH - Treatment Outcome -PMC - PMC3783139 -OTO - NOTNLM -OT - Cardiomyopathies/genetics/pathology/therapy -OT - DNA, mitochondrial/analysis/genetics -OT - electron transport/physiology -OT - energy metabolism/physiology -OT - genetic predisposition to disease -OT - heart diseases/genetics -OT - mitochondria/physiology -OT - mitochondrial diseases/complications/diagnosis/genetics/physiopathology/drug - therapy -OT - risk factors -OT - ventricular dysfunction, left/genetics -EDAT- 2013/10/02 06:00 -MHDA- 2014/05/28 06:00 -PMCR- 2013/01/01 -CRDT- 2013/10/02 06:00 -PHST- 2013/10/02 06:00 [entrez] -PHST- 2013/10/02 06:00 [pubmed] -PHST- 2014/05/28 06:00 [medline] -PHST- 2013/01/01 00:00 [pmc-release] -AID - 0010801-201309000-00007 [pii] -PST - ppublish -SO - Tex Heart Inst J. 2013;40(4):385-94. - -PMID- 22426867 -OWN - NLM -STAT- MEDLINE -DCOM- 20120504 -LR - 20220317 -IS - 1438-9010 (Electronic) -IS - 1438-9010 (Linking) -VI - 184 -IP - 4 -DP - 2012 Apr -TI - [Consensus recommendations of the German Radiology Society (DRG), the German - Cardiac Society (DGK) and the German Society for Pediatric Cardiology (DGPK) on - the use of cardiac imaging with computed tomography and magnetic resonance - imaging]. -PG - 345-68 -LID - 10.1055/s-0031-1299400 [doi] -AB - Cardiac magnetic resonance imaging (MRI) and computed tomography (CT) have been - developed rapidly in the last decade. Technical improvements and broad - availability of modern CT and MRI scanners have led to an increasing and regular - use of both diagnostic methods in clinical routine. Therefore, this German - consensus document has been developed in collaboration by the German Cardiac - Society, German Radiology Society, and the German Society for Pediatric - Cardiology. It is not oriented on modalities and methods, but rather on disease - entities. This consensus document deals with coronary artery disease, - cardiomyopathies, arrhythmias, valvular diseases, pericardial diseases and - structural changes, as well as with congenital heart defects. For different - clinical scenarios both imaging modalities CT and MRI are compared and evaluated - in the specific context. -CI - © Georg Thieme Verlag KG Stuttgart · New York. -FAU - Achenbach, S -AU - Achenbach S -AD - Asklepios Klinik, Altona, Paul-Ehrlich-Str., 22763 Hamburg. -FAU - Barkhausen, J -AU - Barkhausen J -FAU - Beer, M -AU - Beer M -FAU - Beerbaum, P -AU - Beerbaum P -FAU - Dill, T -AU - Dill T -FAU - Eichhorn, J -AU - Eichhorn J -FAU - Fratz, S -AU - Fratz S -FAU - Gutberlet, M -AU - Gutberlet M -FAU - Hoffmann, M -AU - Hoffmann M -FAU - Huber, A -AU - Huber A -FAU - Hunold, P -AU - Hunold P -FAU - Klein, C -AU - Klein C -FAU - Krombach, G -AU - Krombach G -FAU - Kreitner, K-F -AU - Kreitner KF -FAU - Kühne, T -AU - Kühne T -FAU - Lotz, J -AU - Lotz J -FAU - Maintz, D -AU - Maintz D -FAU - Mahrholdt, H -AU - Mahrholdt H -FAU - Merkle, N -AU - Merkle N -FAU - Messroghli, D -AU - Messroghli D -FAU - Miller, S -AU - Miller S -FAU - Paetsch, I -AU - Paetsch I -FAU - Radke, P -AU - Radke P -FAU - Steen, H -AU - Steen H -FAU - Thiele, H -AU - Thiele H -FAU - Sarikouch, S -AU - Sarikouch S -FAU - Fischbach, R -AU - Fischbach R -LA - ger -PT - Consensus Development Conference -PT - English Abstract -PT - Journal Article -PT - Practice Guideline -TT - Konsensusempfehlungen der DRG/DGK/DGPK zum Einsatz der Herzbildgebung mit - Computertomografie und Magnetresonanztomografie. -DEP - 20120317 -PL - Germany -TA - Rofo -JT - RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin -JID - 7507497 -SB - IM -EIN - Rofo. 2012 Apr;184(4):E1. Marholdt, H [corrected to Mahrholdt, H] -MH - Adult -MH - Cardiac Imaging Techniques/*methods -MH - Child -MH - Cooperative Behavior -MH - Germany -MH - Heart Defects, Congenital/*diagnosis/physiopathology/therapy -MH - Heart Diseases/*diagnosis/physiopathology/therapy -MH - Humans -MH - Infant -MH - Interdisciplinary Communication -MH - Magnetic Resonance Imaging/*methods -MH - Prognosis -MH - Sensitivity and Specificity -MH - Tomography, X-Ray Computed/*methods -EDAT- 2012/03/20 06:00 -MHDA- 2012/05/05 06:00 -CRDT- 2012/03/20 06:00 -PHST- 2012/03/20 06:00 [entrez] -PHST- 2012/03/20 06:00 [pubmed] -PHST- 2012/05/05 06:00 [medline] -AID - 10.1055/s-0031-1299400 [doi] -PST - ppublish -SO - Rofo. 2012 Apr;184(4):345-68. doi: 10.1055/s-0031-1299400. Epub 2012 Mar 17. - -PMID- 20841330 -OWN - NLM -STAT- MEDLINE -DCOM- 20111129 -LR - 20161125 -IS - 1469-0756 (Electronic) -IS - 0032-5473 (Linking) -VI - 86 -IP - 1019 -DP - 2010 Sep -TI - Ischaemic heart disease assessment by cardiovascular magnetic resonance imaging. -PG - 532-40 -LID - 10.1136/pgmj.2009.093856 [doi] -AB - Ischaemic heart disease (IHD) related mortality has been on the decline, although - its prevalence has been on the rise since the late 1970s. One of the contributing - factors to this decline has been improved diagnosis and therapeutic management. - Every clinician seeks to answer four key questions while evaluating patients with - suspected or known IHD: What is the global ventricular function? What is the - regional ventricular function? Is the myocardium viable? What is the status of - the coronary arteries? In the past decade cardiovascular magnetic resonance (CMR) - imaging has emerged as an important clinical technique with the potential of - answering all the pertinent questions in a single study. This has led to a - significant increase in demand and utilisation of this modality. However, many - clinicians are not well versed with this technology, its clinical utility, - limitations and future prospects. With the increasing prevalence of IHD, CMR - imaging is likely to be used more often in its diagnosis, prognostication and - management. The review describes the basic principles and practical aspects of - CMR imaging, and then discusses in detail the role of CMR in the diagnosis and - management of IHD, its complications, and its utility in patients with acute - myocardial infarction. -FAU - Raj, Vimal -AU - Raj V -AD - Radiology Department, Papworth Hospital NHS Trust, Cambridge, UK. -FAU - Agrawal, S K -AU - Agrawal SK -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Postgrad Med J -JT - Postgraduate medical journal -JID - 0234135 -SB - IM -CIN - Postgrad Med J. 2010 Sep;86(1019):513-4. doi: 10.1136/pgmj.2010.099283. PMID: - 20576630 -MH - Female -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Male -MH - Myocardial Ischemia/*diagnosis/mortality -MH - Myocardium -MH - United Kingdom -EDAT- 2010/09/16 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2010/09/16 06:00 -PHST- 2010/09/16 06:00 [entrez] -PHST- 2010/09/16 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -AID - 86/1019/532 [pii] -AID - 10.1136/pgmj.2009.093856 [doi] -PST - ppublish -SO - Postgrad Med J. 2010 Sep;86(1019):532-40. doi: 10.1136/pgmj.2009.093856. - -PMID- 23966569 -OWN - NLM -STAT- MEDLINE -DCOM- 20150526 -LR - 20150401 -IS - 1940-1574 (Electronic) -IS - 0003-3197 (Linking) -VI - 65 -IP - 6 -DP - 2014 Jul -TI - Antiplatelet treatment in the secondary prevention of coronary and - cerebrovascular disease: is there any place for novel agents? -PG - 473-90 -LID - 10.1177/0003319713499609 [doi] -AB - Ischemic heart disease and cerebrovascular disease remain major health problems - with associated mortality and quality-of-life consequences. Antiplatelet agents, - including thienopyridines and the new P2Y12 inhibitors, have been shown to - improve survival in the secondary prevention setting. We review the available - evidence on the effectiveness and safety of previous established as well as novel - antithrombotic agents in the secondary prevention of cardiovascular disease with - a special focus on cerebrovascular disease. -CI - © The Author(s) 2013. -FAU - Ntalas, Ioannis V -AU - Ntalas IV -AD - Department of Cardiology, University of Ioannina, Medical School, Ioannina, - Greece dr.ntalas@gmail.com. -FAU - Milionis, Haralampos J -AU - Milionis HJ -AD - Department of Internal Medicine, University of Ioannina, Medical School, - Ioannina, Greece. -FAU - Kei, Anastazia A -AU - Kei AA -AD - Department of Internal Medicine, University of Ioannina, Medical School, - Ioannina, Greece. -FAU - Kalantzi, Kallirroi I -AU - Kalantzi KI -AD - Department of Cardiology, University of Ioannina, Medical School, Ioannina, - Greece. -FAU - Goudevenos, John A -AU - Goudevenos JA -AD - Department of Cardiology, University of Ioannina, Medical School, Ioannina, - Greece. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130821 -PL - United States -TA - Angiology -JT - Angiology -JID - 0203706 -RN - 0 (Factor Xa Inhibitors) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Drug Therapy, Combination -MH - Factor Xa Inhibitors/therapeutic use -MH - Fibrinolytic Agents/therapeutic use -MH - Humans -MH - Ischemic Attack, Transient/*prevention & control -MH - Myocardial Infarction/*prevention & control -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - *Secondary Prevention -MH - Stroke/*prevention & control -OTO - NOTNLM -OT - antiplatelet agents -OT - aspirin -OT - clopidogrel -OT - prasugrel -OT - stroke -OT - ticagrelor -EDAT- 2013/08/24 06:00 -MHDA- 2015/05/27 06:00 -CRDT- 2013/08/23 06:00 -PHST- 2013/08/23 06:00 [entrez] -PHST- 2013/08/24 06:00 [pubmed] -PHST- 2015/05/27 06:00 [medline] -AID - 0003319713499609 [pii] -AID - 10.1177/0003319713499609 [doi] -PST - ppublish -SO - Angiology. 2014 Jul;65(6):473-90. doi: 10.1177/0003319713499609. Epub 2013 Aug - 21. - -PMID- 17081096 -OWN - NLM -STAT- MEDLINE -DCOM- 20061121 -LR - 20220409 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Linking) -VI - 4 -IP - 5 -DP - 2006 Sep -TI - Targeting angiogenesis versus myogenesis with cardiac cell therapy. -PG - 745-53 -AB - Considerable hope has been vested in cell therapy strategies designed to augment - the endogenous neovascularization response to obstructive coronary artery - disease, and to replace cardiomyocyte loss caused by myocardial infarction. - Conceptually, the relative importance of targeting angiogenesis versus myogenesis - in this scheme will vary depending on the clinical context (the predominance of - ischemia versus ventricular dysfunction and scarring). Although the evidence so - far is encouraging, whether these processes can be effectively targeted in a - selective fashion with cell therapy is still unclear. Intriguingly, data are now - emerging suggesting that the beneficial effects of cardiac cell therapies in a - variety of clinical settings may be accounted for by a greater interaction of - angiogenesis, myocardial salvage and myogenesis than heretofore appreciated, and - through mechanisms that may include both cellular and paracrine effects. Greater - understanding of these mechanisms should accelerate the development of effective - cell therapies for the growing number of patients with advanced, and in many - cases 'no-option', cardiovascular disease. Possible clinical targets for - angiogenic and myogenic cardiac cell therapy, the scientific rationale for this - therapeutic approach and future directions in this field are discussed here. -FAU - Doyle, Brendan -AU - Doyle B -AD - University College Cork, Biosciences Institute Rm 4.07, Cork, Ireland. - n.caplice@ucc.ie -FAU - Caplice, Noel M -AU - Caplice NM -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/pathology/*physiopathology/*surgery -MH - Cell Division -MH - *Cell Transplantation -MH - Heart/physiopathology -MH - Humans -MH - Myocytes, Cardiac/*pathology -MH - *Neovascularization, Physiologic -MH - Regeneration -RF - 89 -EDAT- 2006/11/04 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/11/04 09:00 -PHST- 2006/11/04 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/11/04 09:00 [entrez] -AID - 10.1586/14779072.4.5.745 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2006 Sep;4(5):745-53. doi: 10.1586/14779072.4.5.745. - -PMID- 21076292 -OWN - NLM -STAT- MEDLINE -DCOM- 20110824 -LR - 20131121 -IS - 1473-6519 (Electronic) -IS - 1363-1950 (Linking) -VI - 14 -IP - 1 -DP - 2011 Jan -TI - Taurine in cardiovascular disease. -PG - 57-60 -LID - 10.1097/MCO.0b013e328340d863 [doi] -AB - PURPOSE OF REVIEW: The shift of modern dietary regimens from 'Mediterranean' to - 'western' style is believed to be responsible, in part, for the increase in - cardiovascular disease, obesity, type II diabetes and cancer. A classic - 'Mediterranean' diet consists of adequate intake of seafood, vegetables, fruit, - whole grain and nonpurified monounsaturated vegetable oil. Thus, in humans, - dietary intake of seafood is the major source of taurine, as the level of - endogenously produced taurine is low. RECENT FINDINGS: Taurine has been shown to - affect coronary artery disease, blood pressure, plasma cholesterol and myocardial - function in animal models of human disease. A major role of taurine is to act as - an antioxidant and absorb hypochlorous acid but not the oxidative radical. It - seems that this beneficial effect of taurine in antioxidant therapy has not been - well promoted. SUMMARY: This review will focus on determining whether taurine - could be a factor contributing to the further prevention of heart disease. -FAU - Zulli, Anthony -AU - Zulli A -AD - School of Biomedical and Health Science, Victoria University, St Albans, - Victoria, Australia. Anthony.Zulli@vu.edu.au -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Curr Opin Clin Nutr Metab Care -JT - Current opinion in clinical nutrition and metabolic care -JID - 9804399 -RN - 0 (Antioxidants) -RN - 1EQV5MLY3D (Taurine) -RN - 712K4CDC10 (Hypochlorous Acid) -SB - IM -MH - Animals -MH - Antioxidants/metabolism/*pharmacology/therapeutic use -MH - Cardiovascular Diseases/metabolism/*prevention & control -MH - Diet, Mediterranean -MH - Humans -MH - Hypochlorous Acid/metabolism -MH - Seafood -MH - Taurine/metabolism/*pharmacology/therapeutic use -EDAT- 2010/11/16 06:00 -MHDA- 2011/08/25 06:00 -CRDT- 2010/11/16 06:00 -PHST- 2010/11/16 06:00 [entrez] -PHST- 2010/11/16 06:00 [pubmed] -PHST- 2011/08/25 06:00 [medline] -AID - 10.1097/MCO.0b013e328340d863 [doi] -PST - ppublish -SO - Curr Opin Clin Nutr Metab Care. 2011 Jan;14(1):57-60. doi: - 10.1097/MCO.0b013e328340d863. - -PMID- 19553085 -OWN - NLM -STAT- MEDLINE -DCOM- 20091021 -LR - 20250529 -IS - 1097-6795 (Electronic) -IS - 0894-7317 (Print) -IS - 0894-7317 (Linking) -VI - 22 -IP - 8 -DP - 2009 Aug -TI - Role of serotoninergic pathways in drug-induced valvular heart disease and - diagnostic features by echocardiography. -PG - 883-9 -LID - 10.1016/j.echo.2009.05.002 [doi] -AB - Serotonin plays a significant role in the development of carcinoid heart disease, - which primarily leads to fibrosis and contraction of right-sided heart valves. - Recently, strong evidence has emerged that the use of specific drug classes, such - as ergot alkaloids (for migraine headaches), 5-hydroxytryptamine (5-HT or - serotonin) uptake regulators or inhibitors (for weight reduction), and - ergot-derived dopamine agonists (for Parkinson's disease), can result in - left-sided heart valve damage that resembles carcinoid heart disease. Recent - studies have suggested that both right-sided and left-sided drug-induced heart - valve disease involves increased serotoninergic activity and in particular - activation of the 5-HT receptors, including the 5-HT2B receptor subtype, which - mediate many of the central and peripheral functions of serotonin. G-proteins - that inhibit adenylate cyclase activity mediate the activity of the 5-HT2B - receptor subunit, which is widely expressed in a variety of tissues, including - liver, lung, heart, and coronary and pulmonary arteries; it has also been - reported in embryonic mouse heart, particularly on mouse heart valve leaflets. In - this review, the authors discuss the salient features of serotoninergic - manifestations of both carcinoid heart disease and drug-induced cardiac - valvulopathy, with an emphasis on echocardiographic diagnosis. -FAU - Smith, Sakima A -AU - Smith SA -AD - Cardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular - Division, Washington University School of Medicine, St Louis, Missouri 63110, - USA. -FAU - Waggoner, Alan D -AU - Waggoner AD -FAU - de las Fuentes, Lisa -AU - de las Fuentes L -FAU - Davila-Roman, Victor G -AU - Davila-Roman VG -LA - eng -GR - KL2 RR024994/RR/NCRR NIH HHS/United States -GR - P30 DK056341/DK/NIDDK NIH HHS/United States -GR - TL1 RR024995/RR/NCRR NIH HHS/United States -GR - UL1 RR024992/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090623 -PL - United States -TA - J Am Soc Echocardiogr -JT - Journal of the American Society of Echocardiography : official publication of the - American Society of Echocardiography -JID - 8801388 -RN - 0 (Serotonin Antagonists) -RN - 0 (Serotonin Receptor Agonists) -RN - 333DO1RDJY (Serotonin) -SB - IM -MH - Animals -MH - Echocardiography/*methods -MH - Heart Valve Diseases/chemically induced/diagnostic imaging/*metabolism -MH - Heart Valves/*diagnostic imaging/drug effects/*metabolism -MH - Humans -MH - Mice -MH - Serotonin/*metabolism -MH - Serotonin Antagonists/*adverse effects -MH - Serotonin Receptor Agonists/*adverse effects -PMC - PMC3808845 -MID - NIHMS482618 -EDAT- 2009/06/26 09:00 -MHDA- 2009/10/22 06:00 -PMCR- 2013/10/28 -CRDT- 2009/06/26 09:00 -PHST- 2009/01/04 00:00 [received] -PHST- 2009/06/26 09:00 [entrez] -PHST- 2009/06/26 09:00 [pubmed] -PHST- 2009/10/22 06:00 [medline] -PHST- 2013/10/28 00:00 [pmc-release] -AID - S0894-7317(09)00440-4 [pii] -AID - 10.1016/j.echo.2009.05.002 [doi] -PST - ppublish -SO - J Am Soc Echocardiogr. 2009 Aug;22(8):883-9. doi: 10.1016/j.echo.2009.05.002. - Epub 2009 Jun 23. - -PMID- 22819184 -OWN - NLM -STAT- MEDLINE -DCOM- 20130103 -LR - 20171116 -IS - 2213-0276 (Electronic) -IS - 0755-4982 (Linking) -VI - 41 -IP - 11 -DP - 2012 Nov -TI - [Orthostatic hypotension: implications for the treatment of cardiovascular - diseases]. -PG - 1111-5 -LID - S0755-4982(12)00377-6 [pii] -LID - 10.1016/j.lpm.2012.03.024 [doi] -AB - Several cardiovascular drugs may induce or worsen orthostatic hypotension - especially in patients treated for hypertension, coronary artery disease and - heart failure. Orthostatic hypotension is more frequent in polymedicated elderly - patients with co-morbidities (prevalence 23%). In hypertensive elderly patients, - the combination of three antihypertensive agents including a beta-blocker induces - more frequently orthostatic hypotension. Supplementation in water and especially - salt is generally not recommended in case of hypertension and heart failure. - Education of patient to preventive counter-pressure maneuvers and muscle training - of the lower limbs must be part of treatment. Midodrine causes supine - hypertension in almost 25% of patients precluding to take this medication at the - end of the afternoon. In severe heart failure, midodrine seems to be helpful to - optimize drug treatment in patients suffering from hypotension. -CI - Copyright © 2012 Elsevier Masson SAS. All rights reserved. -FAU - Mansourati, Jacques -AU - Mansourati J -AD - CHRU de Brest, hôpital de La Cavale Blanche, département de cardiologie, 29609 - Brest cedex, France. jacques.mansourati@chu-brest.fr -LA - fre -PT - Journal Article -PT - Review -TT - Hypotension orthostatique : répercussions sur le traitement des maladies - cardiovasculaires. -DEP - 20120721 -PL - France -TA - Presse Med -JT - Presse medicale (Paris, France : 1983) -JID - 8302490 -RN - 0 (Antihypertensive Agents) -RN - 0 (Cardiovascular Agents) -RN - 0 (Drinking Water) -RN - 0 (Vasoconstrictor Agents) -RN - 6YE7PBM15H (Midodrine) -SB - IM -MH - Age Factors -MH - Aged -MH - Antihypertensive Agents/adverse effects -MH - Cardiovascular Agents/*adverse effects -MH - Cardiovascular Diseases/*drug therapy -MH - Contraindications -MH - Drinking Water/administration & dosage -MH - Drug Therapy, Combination/adverse effects -MH - Heart Failure/drug therapy -MH - Humans -MH - Hypotension, Orthostatic/*chemically induced/prevention & control/*therapy -MH - Iatrogenic Disease/prevention & control -MH - Midodrine/therapeutic use -MH - Patient Education as Topic -MH - Polypharmacy -MH - Vasoconstrictor Agents/therapeutic use -EDAT- 2012/07/24 06:00 -MHDA- 2013/01/04 06:00 -CRDT- 2012/07/24 06:00 -PHST- 2012/03/03 00:00 [received] -PHST- 2012/03/14 00:00 [accepted] -PHST- 2012/07/24 06:00 [entrez] -PHST- 2012/07/24 06:00 [pubmed] -PHST- 2013/01/04 06:00 [medline] -AID - S0755-4982(12)00377-6 [pii] -AID - 10.1016/j.lpm.2012.03.024 [doi] -PST - ppublish -SO - Presse Med. 2012 Nov;41(11):1111-5. doi: 10.1016/j.lpm.2012.03.024. Epub 2012 Jul - 21. - -PMID- 22871565 -OWN - NLM -STAT- MEDLINE -DCOM- 20130927 -LR - 20220408 -IS - 1097-685X (Electronic) -IS - 0022-5223 (Linking) -VI - 146 -IP - 2 -DP - 2013 Aug -TI - Angiographic outcomes of radial artery versus saphenous vein in coronary artery - bypass graft surgery: a meta-analysis of randomized controlled trials. -PG - 255-61 -LID - S0022-5223(12)00799-4 [pii] -LID - 10.1016/j.jtcvs.2012.07.014 [doi] -AB - INTRODUCTION: The efficacy of coronary artery bypass graft (CABG) surgery for - patients with ischemic heart disease is dependent on the patency of the selected - conduit. The left internal thoracic artery is considered to be the best conduit - for CABG. However, the preferred conduit between the radial artery (RA) and - saphenous vein (SV) remains controversial. The present meta-analysis aims to - establish the current level IA evidence on patency outcomes comparing the RA and - SV. METHODS: Electronic searches were performed using 6 databases from their - inception to March 2012. Two reviewers independently identified all relevant - randomized controlled trials (RCTs) comparing patency outcomes of RA and SV - grafts after CABG. Data were extracted and meta-analyzed according to - angiographic end points at specified follow-up intervals. RESULTS: Five relevant - RCTs were identified for inclusion in the present meta-analysis. Angiographic - results indicated that the RA was significantly more likely to be completely - patent and less likely to be associated with graft failure or complete occlusion - at 4 years' follow-up and beyond. However, the RA was significantly more likely - to be associated with string sign at 1 year of follow-up. CONCLUSIONS: While - acknowledging the limitations of heterogeneous surgical techniques, results from - the present meta-analysis suggest potential superiority of the RA compared with - the SV at midterm angiographic follow-up. However, the increased incidence of - string sign associated with the RA is of potential clinical concern. Further - research should be directed at correlating angiographic findings of string sign - and graft failure to clinical symptoms and major adverse cardiac and - cerebrovascular events at long-term follow-up. -CI - Copyright © 2013 The American Association for Thoracic Surgery. Published by - Mosby, Inc. All rights reserved. -FAU - Cao, Christopher -AU - Cao C -AD - The Systematic Review Unit, The Collaborative Research Group, Sydney, Australia. -FAU - Manganas, Con -AU - Manganas C -FAU - Horton, Matthew -AU - Horton M -FAU - Bannon, Paul -AU - Bannon P -FAU - Munkholm-Larsen, Stine -AU - Munkholm-Larsen S -FAU - Ang, Su C -AU - Ang SC -FAU - Yan, Tristan D -AU - Yan TD -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -DEP - 20120804 -PL - United States -TA - J Thorac Cardiovasc Surg -JT - The Journal of thoracic and cardiovascular surgery -JID - 0376343 -SB - IM -MH - Chi-Square Distribution -MH - *Coronary Angiography -MH - Coronary Artery Bypass/adverse effects/*methods -MH - Evidence-Based Medicine -MH - Graft Occlusion, Vascular/diagnostic imaging/etiology/physiopathology -MH - Graft Survival -MH - Humans -MH - Odds Ratio -MH - Predictive Value of Tests -MH - Radial Artery/diagnostic imaging/physiopathology/*transplantation -MH - Randomized Controlled Trials as Topic -MH - Risk Factors -MH - Saphenous Vein/diagnostic imaging/physiopathology/*transplantation -MH - Time Factors -MH - Treatment Outcome -MH - Vascular Patency -OTO - NOTNLM -OT - 23.1.1 -OT - 23.1.4 -OT - 23.1.5 -OT - CABG -OT - CI -OT - OR -OT - RA -OT - RCT -OT - SV -OT - TIMI -OT - Thrombolysis in Myocardial Infarction -OT - confidence interval -OT - coronary artery bypass grafting -OT - odds ratio -OT - radial artery -OT - randomized controlled trial -OT - saphenous vein -EDAT- 2012/08/09 06:00 -MHDA- 2013/09/28 06:00 -CRDT- 2012/08/09 06:00 -PHST- 2012/03/15 00:00 [received] -PHST- 2012/05/19 00:00 [revised] -PHST- 2012/07/10 00:00 [accepted] -PHST- 2012/08/09 06:00 [entrez] -PHST- 2012/08/09 06:00 [pubmed] -PHST- 2013/09/28 06:00 [medline] -AID - S0022-5223(12)00799-4 [pii] -AID - 10.1016/j.jtcvs.2012.07.014 [doi] -PST - ppublish -SO - J Thorac Cardiovasc Surg. 2013 Aug;146(2):255-61. doi: - 10.1016/j.jtcvs.2012.07.014. Epub 2012 Aug 4. - -PMID- 21057575 -OWN - NLM -STAT- MEDLINE -DCOM- 20101203 -LR - 20230419 -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Print) -IS - 1176-6344 (Linking) -VI - 6 -DP - 2010 Oct 21 -TI - Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to - current diagnosis and management strategies. -PG - 883-903 -LID - 10.2147/VHRM.S11681 [doi] -AB - Diabetic cardiomyopathy (DCM), although a distinct clinical entity, is also a - part of the diabetic atherosclerosis process. It may be independent of the - coexistence of ischemic heart disease, hypertension, or other macrovascular - complications. Its pathological substrate is characterized by the presence of - myocardial damage, reactive hypertrophy, and intermediary fibrosis, structural - and functional changes of the small coronary vessels, disturbance of the - management of the metabolic cardiovascular load, and cardiac autonomic - neuropathy. These alterations make the diabetic heart susceptible to ischemia and - less able to recover from an ischemic attack. Arterial hypertension frequently - coexists with and exacerbates cardiac functioning, leading to the premature - appearance of heart failure. Classical and newer echocardiographic methods are - available for early diagnosis. Currently, there is no specific treatment for DCM; - targeting its pathophysiological substrate by effective risk management protects - the myocardium from further damage and has a recognized primary role in its - prevention. Its pathophysiological substrate is also the objective for the new - therapies and alternative remedies. -FAU - Voulgari, Christina -AU - Voulgari C -AD - First Department of Propaedeutic and Internal Medicine, Athens University Medical - School, Laiko General Hospital, Athens, Greece. c_v_24@yahoo.gr -FAU - Papadogiannis, Dimitrios -AU - Papadogiannis D -FAU - Tentolouris, Nicholas -AU - Tentolouris N -LA - eng -PT - Journal Article -PT - Review -DEP - 20101021 -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -SB - IM -MH - Animals -MH - Cardiomyopathies/diagnosis/*etiology/physiopathology/therapy -MH - Diabetes Complications/diagnosis/*physiopathology/therapy -MH - Echocardiography -MH - Humans -MH - Hyperglycemia/complications/physiopathology -MH - Hypertension/complications/prevention & control -MH - Insulin Resistance/physiology -MH - Metabolic Syndrome/complications/physiopathology -MH - Muscle Cells/*physiology -MH - Risk Factors -PMC - PMC2964943 -OTO - NOTNLM -OT - atherosclerosis -OT - cardiac autonomic neuropathy -OT - cardiovascular disease -OT - echocardiography -OT - treatment strategies -EDAT- 2010/11/09 06:00 -MHDA- 2010/12/14 06:00 -PMCR- 2010/10/21 -CRDT- 2010/11/09 06:00 -PHST- 2010/11/09 06:00 [entrez] -PHST- 2010/11/09 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -PHST- 2010/10/21 00:00 [pmc-release] -AID - vhrm-6-883 [pii] -AID - 10.2147/VHRM.S11681 [doi] -PST - epublish -SO - Vasc Health Risk Manag. 2010 Oct 21;6:883-903. doi: 10.2147/VHRM.S11681. - -PMID- 19917337 -OWN - NLM -STAT- MEDLINE -DCOM- 20100107 -LR - 20130502 -IS - 1873-1740 (Electronic) -IS - 0033-0620 (Linking) -VI - 52 -IP - 3 -DP - 2009 Nov-Dec -TI - Flash pulmonary edema. -PG - 249-59 -LID - 10.1016/j.pcad.2009.10.002 [doi] -AB - Flash pulmonary edema (FPE) is a general clinical term used to describe a - particularly dramatic form of acute decompensated heart failure. Well-established - risk factors for heart failure such as hypertension, coronary ischemia, valvular - heart disease, and diastolic dysfunction are associated with acute decompensated - heart failure as well as with FPE. However, endothelial dysfunction possibly - secondary to an excessive activity of renin-angiotensin-aldosterone system, - impaired nitric oxide synthesis, increased endothelin levels, and/or excessive - circulating catecholamines may cause excessive pulmonary capillary permeability - and facilitate FPE formation. Renal artery stenosis particularly when bilateral - has been identified has a common cause of FPE. Lack of diurnal variation in blood - pressure and a widened pulse pressure have been identified as risk factors for - FPE. This review is an attempt to delineate clinical and pathophysiological - mechanisms responsible for FPE and to distinguish pathophysiologic, clinical, and - therapeutic aspects of FPE from those of acute decompensated heart failure. -FAU - Rimoldi, Stefano F -AU - Rimoldi SF -AD - Swiss Cardiovascular Center Bern, University Hospital, Bern, Switzerland. - stefano.rimoldi@insel.ch -FAU - Yuzefpolskaya, Melana -AU - Yuzefpolskaya M -FAU - Allemann, Yves -AU - Allemann Y -FAU - Messerli, Franz -AU - Messerli F -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Prog Cardiovasc Dis -JT - Progress in cardiovascular diseases -JID - 0376442 -SB - IM -MH - Diagnosis, Differential -MH - Heart Failure/diagnosis/etiology/physiopathology -MH - Humans -MH - Pulmonary Edema/diagnosis/*etiology/*physiopathology -MH - Renin-Angiotensin System/physiology -MH - Risk Factors -RF - 112 -EDAT- 2009/11/18 06:00 -MHDA- 2010/01/08 06:00 -CRDT- 2009/11/18 06:00 -PHST- 2009/11/18 06:00 [entrez] -PHST- 2009/11/18 06:00 [pubmed] -PHST- 2010/01/08 06:00 [medline] -AID - S0033-0620(09)00082-6 [pii] -AID - 10.1016/j.pcad.2009.10.002 [doi] -PST - ppublish -SO - Prog Cardiovasc Dis. 2009 Nov-Dec;52(3):249-59. doi: 10.1016/j.pcad.2009.10.002. - -PMID- 20549843 -OWN - NLM -STAT- MEDLINE -DCOM- 20110602 -LR - 20191027 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 25 -IP - 4 -DP - 2010 Jul -TI - Lipid-lowering drugs and heart failure: where do we go after the statin trials? -PG - 385-93 -AB - PURPOSE OF REVIEW: Heart failure is an important cause of disease burden in aging - societies. Although HMG-CoA reductase inhibitors (statins) prevent important - causative factors for heart failure, myocardial damage and ischemia, the benefits - of statins and low-density lipoprotein (LDL) lowering in heart failure patients - have been questioned. The role of other types of dyslipidemia [low high-density - lipoprotein (HDL), high triglycerides] and their modification has received less - attention in heart failure thus far. RECENT FINDINGS: In patients with coronary - artery disease (CAD), or at high risk thereof, statin treatment prevents heart - failure. Moreover, intensive statin treatment is better than usual doses. - However, initiation of even an effective statin in patients with established, and - especially advanced, heart failure has not improved prognosis. Statin treatment - may, however, reduce complications and, importantly, has not proved to be harmful - in randomized trials. Variables related to HDL metabolism are associated with - heart failure in several studies, but trial evidence of HDL or - triglyceride-modifying therapies is scant. SUMMARY: Whereas statins are important - in preventing or postponing heart failure in the first place, their initiation in - established heart failure does not improve prognosis. On the contrary, - discontinuation of statin treatment is not indicated due to development of heart - failure. Combination therapies of both LDL and HDL may offer more effective - possibilities for heart failure prevention. -FAU - Strandberg, Timo E -AU - Strandberg TE -AD - Institute of Health Sciences/Geriatrics, University of Oulu, Oulu University - Hospital, Oulu, Finland. timo.strandberg@oulu.fi -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Cholesterol, HDL) -RN - 0 (Cholesterol, LDL) -RN - 0 (Heptanoic Acids) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Pyrroles) -RN - 0 (Triglycerides) -RN - A0JWA85V8F (Atorvastatin) -RN - KXO2KT9N0G (Pravastatin) -SB - IM -MH - Anticholesteremic Agents/*therapeutic use -MH - Atorvastatin -MH - Cholesterol, HDL/drug effects -MH - Cholesterol, LDL/*drug effects -MH - Disease Progression -MH - Heart Failure/*drug therapy/prevention & control -MH - Heptanoic Acids/therapeutic use -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Hyperlipidemias/*drug therapy -MH - Pravastatin/therapeutic use -MH - Primary Prevention -MH - Prognosis -MH - Pyrroles/therapeutic use -MH - Risk Factors -MH - Secondary Prevention -MH - Triglycerides -RF - 44 -EDAT- 2010/06/16 06:00 -MHDA- 2011/06/03 06:00 -CRDT- 2010/06/16 06:00 -PHST- 2010/06/16 06:00 [entrez] -PHST- 2010/06/16 06:00 [pubmed] -PHST- 2011/06/03 06:00 [medline] -AID - 10.1097/hco.0b013e328338bc2d [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2010 Jul;25(4):385-93. doi: 10.1097/hco.0b013e328338bc2d. - -PMID- 23123443 -OWN - NLM -STAT- MEDLINE -DCOM- 20130429 -LR - 20211021 -IS - 1879-0631 (Electronic) -IS - 0024-3205 (Print) -IS - 0024-3205 (Linking) -VI - 92 -IP - 11 -DP - 2013 Mar 28 -TI - Diabetic cardiomyopathy and metabolic remodeling of the heart. -PG - 609-15 -LID - S0024-3205(12)00614-5 [pii] -LID - 10.1016/j.lfs.2012.10.011 [doi] -AB - The incidence and prevalence of diabetes mellitus are both increasing rapidly in - societies around the globe. The majority of patients with diabetes succumb - ultimately to heart disease, much of which stems from atherosclerotic disease and - hypertension. However, the diabetic milieu is itself intrinsically noxious to the - heart, and cardiomyopathy can develop independent of elevated blood pressure or - coronary artery disease. This process, termed diabetic cardiomyopathy, is - characterized by significant changes in the physiology, structure, and mechanical - function of the heart. Presently, therapy for patients with diabetes focuses - largely on glucose control, and attention to the heart commences with the onset - of symptoms. When the latter develops, standard therapy for heart failure is - applied. However, recent studies highlight that specific elements of the - pathogenesis of diabetic heart disease are unique, raising the prospect of - diabetes-specific therapeutic intervention. Here, we review recently unveiled - insights into the pathogenesis of diabetic cardiomyopathy and associated - metabolic remodeling with an eye toward identifying novel targets with - therapeutic potential. -CI - Published by Elsevier Inc. -FAU - Battiprolu, Pavan K -AU - Battiprolu PK -AD - Department of Internal Medicine (Cardiology), University of Texas Southwestern - Medical Center, Dallas, TX 75235, USA. -FAU - Lopez-Crisosto, Camila -AU - Lopez-Crisosto C -FAU - Wang, Zhao V -AU - Wang ZV -FAU - Nemchenko, Andriy -AU - Nemchenko A -FAU - Lavandero, Sergio -AU - Lavandero S -FAU - Hill, Joseph A -AU - Hill JA -LA - eng -GR - HL-080144/HL/NHLBI NIH HHS/United States -GR - R01 HL075173/HL/NHLBI NIH HHS/United States -GR - HL-090842/HL/NHLBI NIH HHS/United States -GR - S10 RR023729/RR/NCRR NIH HHS/United States -GR - R01 HL080144/HL/NHLBI NIH HHS/United States -GR - R01 HL120732/HL/NHLBI NIH HHS/United States -GR - HL-075173/HL/NHLBI NIH HHS/United States -GR - R01 HL090842/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121030 -PL - Netherlands -TA - Life Sci -JT - Life sciences -JID - 0375521 -SB - IM -MH - Diabetic Cardiomyopathies/drug therapy/*pathology -MH - Drug Delivery Systems -MH - Humans -MH - *Ventricular Remodeling -PMC - PMC3593804 -MID - NIHMS423562 -COIS- Conflict of interest The authors have declared that no conflicts of interest - exist. -EDAT- 2012/11/06 06:00 -MHDA- 2013/04/30 06:00 -PMCR- 2014/03/28 -CRDT- 2012/11/06 06:00 -PHST- 2012/06/20 00:00 [received] -PHST- 2012/09/12 00:00 [revised] -PHST- 2012/10/04 00:00 [accepted] -PHST- 2012/11/06 06:00 [entrez] -PHST- 2012/11/06 06:00 [pubmed] -PHST- 2013/04/30 06:00 [medline] -PHST- 2014/03/28 00:00 [pmc-release] -AID - S0024-3205(12)00614-5 [pii] -AID - 10.1016/j.lfs.2012.10.011 [doi] -PST - ppublish -SO - Life Sci. 2013 Mar 28;92(11):609-15. doi: 10.1016/j.lfs.2012.10.011. Epub 2012 - Oct 30. - -PMID- 18307738 -OWN - NLM -STAT- MEDLINE -DCOM- 20080522 -LR - 20080229 -IS - 1440-1681 (Electronic) -IS - 0305-1870 (Linking) -VI - 35 -IP - 4 -DP - 2008 Apr -TI - Can measurement of B-type natriuretic peptide levels improve cardiovascular - disease prevention? -PG - 442-6 -LID - 10.1111/j.1440-1681.2008.04894.x [doi] -AB - 1. The measurement of plasma levels of B-type natriuretic peptide (BNP) and - amino-terminal pro-BNP (NT-proBNP) provides useful diagnostic information in - patients with suspected heart failure and valuable prognostic information in - patients with heart failure, acute coronary syndrome, valvular heart disease and - other cardiac pathologies. 2. BNP- and NT-proBNP-guided heart failure therapy - improves patient outcomes. 3. An increasing number of studies shows plasma BNP - and NT-proBNP levels predict all-cause mortality and cardiovascular events - including heart failure, myocardial infarction, stroke, atrial fibrillation and - cardiovascular death in stable patients with or without known cardiovascular - disease and provide information about cardiovascular risk additional to that - provided by traditional risk factors. 4. Antihypertensive therapy reduces - elevated NT-proBNP levels in individuals at increased cardiovascular risk, - thereby suggesting that change in NT-proBNP levels provides a measure of risk - reduction. 5. Thus, monitoring of BNP and NT-proBNP levels offers the - possibilities of improved targeting of individuals with increased cardiovascular - risk and optimization of strategies for primary and secondary prevention of - cardiovascular disease. 6. There is need for an outcome study to determine - whether BNP- or NT-proBNP-guided therapy improves cardiovascular disease - prevention. -FAU - Campbell, Duncan J -AU - Campbell DJ -AD - St Vincent's Institute of Medical Research and the Department of Medicine, - University of Melbourne, St Vincent's Hospital, Fitzroy, Victoria, Australia. - dcampbell@svi.edu.autoria -LA - eng -PT - Journal Article -PT - Review -PL - Australia -TA - Clin Exp Pharmacol Physiol -JT - Clinical and experimental pharmacology & physiology -JID - 0425076 -RN - 0 (Peptide Fragments) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Cardiovascular Diseases/*blood/*prevention & control -MH - Humans -MH - Natriuretic Peptide, Brain/*blood -MH - Peptide Fragments/*blood -MH - Risk Factors -RF - 60 -EDAT- 2008/03/01 09:00 -MHDA- 2008/05/23 09:00 -CRDT- 2008/03/01 09:00 -PHST- 2008/03/01 09:00 [pubmed] -PHST- 2008/05/23 09:00 [medline] -PHST- 2008/03/01 09:00 [entrez] -AID - CEP4894 [pii] -AID - 10.1111/j.1440-1681.2008.04894.x [doi] -PST - ppublish -SO - Clin Exp Pharmacol Physiol. 2008 Apr;35(4):442-6. doi: - 10.1111/j.1440-1681.2008.04894.x. - -PMID- 23716129 -OWN - NLM -STAT- MEDLINE -DCOM- 20140214 -LR - 20211021 -IS - 1937-5395 (Electronic) -IS - 1937-5387 (Linking) -VI - 6 -IP - 4 -DP - 2013 Aug -TI - MicroRNAs as biomarkers for ischemic heart disease. -PG - 458-70 -LID - 10.1007/s12265-013-9466-z [doi] -AB - MicroRNAs (miRs) are short, noncoding RNAs that function as posttranscriptional - inhibitors of mRNA translation to protein. They are essential for normal - development and homeostasis. Dysregulated expression patterns both cause and - result from disease states. Generally studied as intracellular mediators, miRs - can be isolated from body fluids and exhibit remarkable stability to degradation. - These features, in combination with their tissue specificity, make miRs - attractive candidates as blood-derived biomarkers for coronary artery disease - (CAD), the most frequent cause of death worldwide. The use of miRs as biomarkers - in both symptomatic and asymptomatic CAD and the influence of conventional - cardiovascular risk factors and CAD treatment on their circulating levels are the - topics of this review. To conclude, it highlights the remaining hurdles to tackle - before this promising application of miRs can enter into routine clinical - practice. -FAU - Van Aelst, Lucas N L -AU - Van Aelst LN -AD - Center for Molecular and Vascular Biology, University of Leuven, Herestraat 49, - Box 911, 3000, Leuven, Belgium. -FAU - Heymans, Stephane -AU - Heymans S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130529 -PL - United States -TA - J Cardiovasc Transl Res -JT - Journal of cardiovascular translational research -JID - 101468585 -RN - 0 (Genetic Markers) -RN - 0 (MicroRNAs) -SB - IM -MH - Animals -MH - Genetic Markers -MH - *Genetic Testing/methods -MH - Humans -MH - MicroRNAs/*analysis -MH - Myocardial Ischemia/*diagnosis/genetics -MH - Predictive Value of Tests -MH - Prognosis -MH - Reproducibility of Results -EDAT- 2013/05/30 06:00 -MHDA- 2014/02/15 06:00 -CRDT- 2013/05/30 06:00 -PHST- 2013/02/21 00:00 [received] -PHST- 2013/04/19 00:00 [accepted] -PHST- 2013/05/30 06:00 [entrez] -PHST- 2013/05/30 06:00 [pubmed] -PHST- 2014/02/15 06:00 [medline] -AID - 10.1007/s12265-013-9466-z [doi] -PST - ppublish -SO - J Cardiovasc Transl Res. 2013 Aug;6(4):458-70. doi: 10.1007/s12265-013-9466-z. - Epub 2013 May 29. - -PMID- 20873315 -OWN - NLM -STAT- MEDLINE -DCOM- 20101020 -LR - 20190923 -IS - 0025-8105 (Print) -IS - 0025-8105 (Linking) -VI - 63 -IP - 1-2 -DP - 2010 Jan-Feb -TI - [Medical treatments in aortic stenosis: role of statins and - angiotensin-converting enzyme inhibitors]. -PG - 82-5 -AB - CALCIFIC AROTIC STENOSIS AND ATHEROSCLEROSIS: Aortic stenosis is the most - frequent valvular heart disease in western world and its incidence continues to - rise. Aortic sclerosis is the first characteristic lesion of the cusps, which is - today considered a process similar to atherosclerosis. The progression of the - disease is an active process leading to forming of bone matrix and heavily - calcified stiff cusps by inflammatory cells and osteopontin. Aortic stenosis is a - chronic, progressive disease which can remain asymptomatic for a long time even - in the presence of severe aortic stenosis. MEDICAL TREATMENT FOR AORTIC STENOSIS: - The need for alternative to aortic valve surgery is highlighted by increasing - longevity of the population and new therapeutic strategies to limit disease - progression are needed to delay or potentially avoid, the need for valve surgery. - Currently, there are no established disease modifying treatments in regard to the - progression of aortic stenosis. The first results about influence of - angiotensin-converting enzyme inhibitors and statins on aortic sclerosis and - stenosis progression are promising. Statins are likely to reduce cardiovascular - events rather than disease progression, but may be potentially a valuable - preventive treatment in these patients. The prejudice against the use of - angiotensin-converting enzyme inhibitors by patients with aortic stenosis is - changing. The cautious use of angiotensin-converting enzyme inhibition by - patients with concomitant hypertension, coronary artery disease, and heart - failure seems appropriate. Definite evidence from large clinical trials is - awaited. -FAU - Davicević, Zaklina -AU - Davicević Z -AD - Klinika za kardiologiju, Vojnomedicinska akademija, Beograd. zak71@eunet.yu -FAU - Tavciovski, Dragan -AU - Tavciovski D -FAU - Matunović, Radomir -AU - Matunović R -LA - srp -PT - English Abstract -PT - Journal Article -PT - Review -PL - Serbia -TA - Med Pregl -JT - Medicinski pregled -JID - 2985249R -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Angiotensin-Converting Enzyme Inhibitors/*therapeutic use -MH - Aortic Valve Stenosis/*drug therapy -MH - Disease Progression -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -EDAT- 2010/09/29 06:00 -MHDA- 2010/10/21 06:00 -CRDT- 2010/09/29 06:00 -PHST- 2010/09/29 06:00 [entrez] -PHST- 2010/09/29 06:00 [pubmed] -PHST- 2010/10/21 06:00 [medline] -AID - 10.2298/mpns1002082d [doi] -PST - ppublish -SO - Med Pregl. 2010 Jan-Feb;63(1-2):82-5. doi: 10.2298/mpns1002082d. - -PMID- 21485420 -OWN - NLM -STAT- MEDLINE -DCOM- 20110624 -LR - 20110405 -IS - 1936-2692 (Electronic) -IS - 1088-0224 (Linking) -VI - 17 -IP - 1 -DP - 2011 Jan -TI - Telephone-based disease management: why it does not save money. -PG - e10-6 -AB - OBJECTIVES: To understand why the current telephone-based model of disease - management (DM) does not provide cost savings and how DM can be retooled based on - the best available evidence to deliver better value. STUDY DESIGN: Literature - review. METHODS: The published peer-reviewed evaluations of DM and transitional - care models from 1990 to 2010 were reviewed. Also examined was the - cost-effectiveness literature on the treatment of chronic conditions that are - commonly included in DM programs, including heart failure, diabetes mellitus, - coronary artery disease, and asthma. RESULTS: First, transitional care models, - which have historically been confused with commercial DM programs, can provide - credible savings over a short period, rendering them low-hanging fruit for plan - sponsors who desire real savings. Second, cost-effectiveness research has shown - that the individual activities that constitute contemporary DM programs are not - cost saving except for heart failure. Targeting of specific patients and activity - combinations based on risk, actionability, treatment and program effectiveness, - and costs will be necessary to deliver a cost-saving DM program, combined with an - outreach model that brings vendors closer to the patient and physician. Barriers - to this evidence-driven approach include resources required, marketability, and - business model disruption. CONCLUSIONS: After a decade of market experimentation - with limited success, new thinking is called for in the design of DM programs. A - program design that is based on a cost-effectiveness approach, combined with - greater program efficacy, will allow for the development of DM programs that are - cost saving. -FAU - Motheral, Brenda R -AU - Motheral BR -AD - CareScientific, Brentwood, TN 37027, USA. bmotheral@carescientific.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Manag Care -JT - The American journal of managed care -JID - 9613960 -CIN - Am J Manag Care. 2011 Mar;17(3):e89-90; author reply e90. PMID: 21650064 -MH - Chronic Disease -MH - *Continuity of Patient Care -MH - Cost Savings -MH - Cost-Benefit Analysis -MH - *Disease Management -MH - Health Care Costs -MH - *Hotlines -MH - Humans -MH - Models, Economic -MH - United States -EDAT- 2011/04/13 06:00 -MHDA- 2011/06/28 06:00 -CRDT- 2011/04/13 06:00 -PHST- 2011/04/13 06:00 [entrez] -PHST- 2011/04/13 06:00 [pubmed] -PHST- 2011/06/28 06:00 [medline] -AID - 12800 [pii] -PST - ppublish -SO - Am J Manag Care. 2011 Jan;17(1):e10-6. - -PMID- 22002260 -OWN - NLM -STAT- MEDLINE -DCOM- 20130507 -LR - 20211020 -IS - 1573-7322 (Electronic) -IS - 1382-4147 (Linking) -VI - 17 -IP - 4-5 -DP - 2012 Sep -TI - Systolic heart failure in the elderly: optimizing medical management. -PG - 563-71 -LID - 10.1007/s10741-011-9282-y [doi] -AB - The aging population with hypertension and coronary artery disease is rapidly - increasing worldwide and develops heart failure (HF). A wide range of - pharmacotherapeutic drugs are recommended in the HF management guidelines. For - the most part, these recommendations are based on the results of studies in the - younger population, and most drugs were not adequately tested in the elderly. - However, many changes that occur during the aging process affect the response to - several of the recommended therapeutic drugs. Physicians will be increasingly - involved in managing the expanding elderly population with HF. It is therefore - imperative that they recognize ways to use current pharmacotherapeutic agents and - the increasing need for novel agents for optimizing the management of the elderly - patient with HF. -FAU - Man, Jonathan P -AU - Man JP -AD - Hospital of the University of Pennsylvania-Cardiology, 3400 Spruce Street, - Philadelphia, PA 19104, USA. jonathan.man@uphs.upenn.edu -FAU - Jugdutt, Bodh I -AU - Jugdutt BI -LA - eng -GR - IAP-99003/Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin Receptor Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Cardiovascular Agents) -RN - 0 (Diuretics) -RN - 0 (Mineralocorticoid Receptor Antagonists) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Aged -MH - Aging/*physiology -MH - Angiotensin Receptor Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Cardiovascular Agents/*therapeutic use -MH - Disease Management -MH - Diuretics/therapeutic use -MH - Female -MH - Heart Failure, Systolic/*drug therapy/physiopathology/therapy -MH - Humans -MH - Male -MH - Mineralocorticoid Receptor Antagonists/therapeutic use -EDAT- 2011/10/18 06:00 -MHDA- 2013/05/08 06:00 -CRDT- 2011/10/18 06:00 -PHST- 2011/10/18 06:00 [entrez] -PHST- 2011/10/18 06:00 [pubmed] -PHST- 2013/05/08 06:00 [medline] -AID - 10.1007/s10741-011-9282-y [doi] -PST - ppublish -SO - Heart Fail Rev. 2012 Sep;17(4-5):563-71. doi: 10.1007/s10741-011-9282-y. - -PMID- 27325929 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20160621 -LR - 20201001 -IS - 1759-1104 (Print) -IS - 1759-1104 (Electronic) -IS - 1759-1104 (Linking) -VI - 1 -IP - 1 -DP - 2009 -TI - Current endovascular therapy for lower extremity peripheral arterial disease: - indications, outcomes and modalities. -PG - 51-7 -LID - 10.1136/ha.2009.000976 [doi] -AB - Atherosclerosis of the lower extremities frequently leads to - lifestyle-restricting claudication and can cause critical limb ischaemia (rest - pain, non-healing ulcer, or gangrene). The prevalence of peripheral arterial - disease (PAD) is rising in line with an ageing population. In the USA, PAD - affects 8-10 million people (approximately 12% of the adult population). There is - a strong association with concomitant coronary artery and cerebral vascular - disease in these patients, which represents a significant cause of mortality and - morbidity in patients with PAD. Disease affecting the lower extremity peripheral - vessels is most aggressive in smokers and diabetics. -FAU - Yan, B P -AU - Yan BP -AD - Division of Cardiology, Department of Medicine & Therapeutics, Prince of Wales - Hospital and The Chinese University of Hong Kong, Hong Kong. -FAU - Kiernan, T J -AU - Kiernan TJ -AD - Division of Cardiology, Massachusetts General Hospital and Harvard Medical - School, Boston Massachusetts, USA. -FAU - Lam, Y-Y -AU - Lam YY -AD - Division of Cardiology, Department of Medicine & Therapeutics, Prince of Wales - Hospital and The Chinese University of Hong Kong, Hong Kong. -FAU - Yu, C-M -AU - Yu CM -AD - Division of Cardiology, Department of Medicine & Therapeutics, Prince of Wales - Hospital and The Chinese University of Hong Kong, Hong Kong. -LA - eng -PT - Journal Article -PT - Review -DEP - 20090101 -PL - England -TA - Heart Asia -JT - Heart Asia -JID - 101542742 -PMC - PMC4898493 -COIS- Competing interests: None declared. -EDAT- 2009/01/01 00:00 -MHDA- 2009/01/01 00:01 -PMCR- 2009/01/01 -CRDT- 2016/06/22 06:00 -PHST- 2009/08/13 00:00 [accepted] -PHST- 2016/06/22 06:00 [entrez] -PHST- 2009/01/01 00:00 [pubmed] -PHST- 2009/01/01 00:01 [medline] -PHST- 2009/01/01 00:00 [pmc-release] -AID - heartasia-2009-000976 [pii] -AID - 10.1136/ha.2009.000976 [doi] -PST - epublish -SO - Heart Asia. 2009 Jan 1;1(1):51-7. doi: 10.1136/ha.2009.000976. eCollection 2009. - -PMID- 24527353 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20240517 -IS - 2162-1918 (Print) -IS - 2162-1934 (Electronic) -IS - 2162-1918 (Linking) -VI - 2 -IP - 6 -DP - 2013 Jul -TI - Cardiac Progenitor Cells in Myocardial Infarction Wound Healing: A Critical - Review. -PG - 317-326 -AB - SIGNIFICANCE: Coronary artery disease is a major cause of morbidity and mortality - as the loss of functional myocardium drives progressive ventricular remodeling - and subsequent heart failure. Medical management has significantly improved - outcomes for acute myocardial infarction (MI); however, improved strategies are - needed to regenerate functional myocardium and prevent the progression to heart - failure. Cytotherapy using cardiac progenitor cells (PCs) to regenerate - functional myocardium holds tremendous potential; however, a better understanding - of PC biology is needed. RECENT ADVANCES: Reports of cardiac regeneration in - lower animals have been reported in the last decade. However, just recently, two - separate models of mammalian cardiac regeneration have been published and offer - potential to better define PC biology, including PC recruitment, differentiation, - proliferation, and integration. CRITICAL ISSUES: Numerous clinical trials have - been completed or are ongoing to evaluate possible cytotherapy options in the - treatment of acute and chronic ischemic cardiac disease. To date, results have - demonstrated improvements in cardiac function as a result of paracrine effects of - cytotherapy, but regeneration of functional myocardium has yet to be observed. - FUTURE DIRECTIONS: Future translation of cardiac PC biology from these models is - necessary to promote regenerative cardiac healing following MI and to prevent the - progression to heart failure following the loss of functional myocardium. - Knowledge gained from mammalian models of cardiac regeneration will allow for the - development of therapeutic regimens in the treatment of heart failure. -FAU - Morris, Michael W Jr -AU - Morris MW Jr -AD - Department of Surgery, University of Mississippi Medical Center , Jackson, - Mississippi. -FAU - Liechty, Kenneth W -AU - Liechty KW -AD - Department of Pediatric Surgery, Nemours Children's Hospital , Orlando, Florida. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Adv Wound Care (New Rochelle) -JT - Advances in wound care -JID - 101590593 -PMC - PMC3751317 -EDAT- 2014/02/15 06:00 -MHDA- 2014/02/15 06:01 -PMCR- 2013/07/01 -CRDT- 2014/02/15 06:00 -PHST- 2012/12/17 00:00 [received] -PHST- 2014/02/15 06:00 [entrez] -PHST- 2014/02/15 06:00 [pubmed] -PHST- 2014/02/15 06:01 [medline] -PHST- 2013/07/01 00:00 [pmc-release] -AID - 10.1089/wound.2012.0390 [pii] -AID - 10.1089/wound.2012.0390 [doi] -PST - ppublish -SO - Adv Wound Care (New Rochelle). 2013 Jul;2(6):317-326. doi: - 10.1089/wound.2012.0390. - -PMID- 20235042 -OWN - NLM -STAT- MEDLINE -DCOM- 20100423 -LR - 20171116 -IS - 0040-5930 (Print) -IS - 0040-5930 (Linking) -VI - 67 -IP - 3 -DP - 2010 Mar -TI - [Cardiovascular disease and sexuality]. -PG - 139-43 -LID - 10.1024/0040-5930/a000026 [doi] -AB - Sexual activity corresponds to light to moderate physical exercise and entails no - significant risk to the majority of patients with cardiovascular disease. In - patients suffering from severe angina or chronic heart failure, however, sexual - activity might trigger coital angina or cardiac decompensation necessitating - hospitalization. Nevertheless, even for patients with coronary artery disease the - absolute risk of having a heart attack or fatal event during sexual activity is - extremely low. Due to systemic atherosclerosis and concomitant endothelial - dysfunction the prevalence of sexual dysfunction is higher in patients with - cardiovascular disease as compared to the general population. PDE-5 inhibitors - can be safely used by many patients suffering from both, cardiovascular disease - and sexual dysfunction as long as no concomitant medication with nitrates exists. - The concomitant use of PDE-5 inhibitors and nitrates is strictly contraindicated - because of the risk of life-threatening hypotension. It is therefore of utmost - importance to ask patients presenting with coital angina about PDE-5 inhibitor - intake before the administration of nitrate-based anti-ischemic therapies. The - recommendations of the Princeton Consensus Conference provide a useful framework - for risk stratification and counseling of patients with cardiovascular disease - regarding sexual activity. -FAU - Pfister, Otmar -AU - Pfister O -AD - Klinik für Kardiologie, Universitätsspital Basel, Basel. -LA - ger -PT - Journal Article -PT - Review -TT - Kardiologische Erkrankungen und Sexualität. -PL - Switzerland -TA - Ther Umsch -JT - Therapeutische Umschau. Revue therapeutique -JID - 0407224 -RN - 0 (Nitrates) -RN - 0 (Phosphodiesterase 5 Inhibitors) -RN - 0 (Phosphodiesterase Inhibitors) -SB - IM -MH - Angina Pectoris/diagnosis/*physiopathology/therapy -MH - Coitus/physiology -MH - Contraindications -MH - Drug Interactions -MH - Female -MH - Heart Failure/diagnosis/*physiopathology/therapy -MH - Humans -MH - Male -MH - Myocardial Infarction/physiopathology/prevention & control -MH - Myocardial Ischemia/diagnosis/*physiopathology/therapy -MH - Nitrates/adverse effects/therapeutic use -MH - Phosphodiesterase 5 Inhibitors -MH - Phosphodiesterase Inhibitors/adverse effects/therapeutic use -MH - Risk Factors -MH - Secondary Prevention -MH - Sexual Dysfunction, Physiological/diagnosis/*physiopathology/therapy -MH - Sexual Dysfunctions, Psychological/diagnosis/*physiopathology/therapy -RF - 13 -EDAT- 2010/03/18 06:00 -MHDA- 2010/04/24 06:00 -CRDT- 2010/03/18 06:00 -PHST- 2010/03/18 06:00 [entrez] -PHST- 2010/03/18 06:00 [pubmed] -PHST- 2010/04/24 06:00 [medline] -AID - 10.1024/0040-5930/a000026 [doi] -PST - ppublish -SO - Ther Umsch. 2010 Mar;67(3):139-43. doi: 10.1024/0040-5930/a000026. - -PMID- 21625110 -OWN - NLM -STAT- MEDLINE -DCOM- 20111019 -LR - 20190710 -IS - 1662-2782 (Electronic) -IS - 0302-5144 (Linking) -VI - 171 -DP - 2011 -TI - Noninvasive volume assessment in the emergency department: a look at B-type - natriuretic peptide and bioimpedance vector analysis. -PG - 187-193 -LID - 10.1159/000327205 [doi] -AB - B-type natriuretic peptide (BNP) and bioimpedance vector analysis (BIVA) are - potential methods of assessing fluid status in patients. Their speed and ease of - implementation allows them to be used at the point of care. Currently, BNP is - pivotal in the diagnosis and prognosis of heart failure, and is starting to be - implemented in other diseases (e.g. acute coronary syndrome and end-stage renal - disease). Although it can be elevated from volume-overload-induced cardiac - stress, when assessing volume this method is ultimately unreliable since it lacks - adequate specificity and accuracy. Alternatively, BIVA is accurate and sensitive - in the detection of fluid status, but cannot be used to tell the etiology of the - volume aberration. Despite being relatively new, BIVA is becoming recognized as a - superior method to assess volume. -CI - Copyright © 2011 S. Karger AG, Basel. -FAU - Tuy, Tertius -AU - Tuy T -FAU - Peacock, Frank -AU - Peacock F -LA - eng -PT - Journal Article -PT - Review -DEP - 20110523 -PL - Switzerland -TA - Contrib Nephrol -JT - Contributions to nephrology -JID - 7513582 -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Body Water/*metabolism -MH - Electric Impedance -MH - Emergency Service, Hospital -MH - Glomerular Filtration Rate -MH - Humans -MH - Natriuretic Peptide, Brain/*blood -MH - Prognosis -EDAT- 2011/06/01 06:00 -MHDA- 2011/10/20 06:00 -CRDT- 2011/06/01 06:00 -PHST- 2011/06/01 06:00 [entrez] -PHST- 2011/06/01 06:00 [pubmed] -PHST- 2011/10/20 06:00 [medline] -AID - 000327205 [pii] -AID - 10.1159/000327205 [doi] -PST - ppublish -SO - Contrib Nephrol. 2011;171:187-193. doi: 10.1159/000327205. Epub 2011 May 23. - -PMID- 20962429 -OWN - NLM -STAT- MEDLINE -DCOM- 20101130 -LR - 20220410 -IS - 1347-4820 (Electronic) -IS - 1346-9843 (Linking) -VI - 74 -IP - 11 -DP - 2010 Nov -TI - Aging and arterial stiffness. -PG - 2257-62 -AB - Arterial walls stiffen with age. The most consistent and well-reported changes - are luminal enlargement with wall thickening and a reduction of elastic - properties at the level of large elastic arteries. Longstanding arterial - pulsation in the central artery causes elastin fiber fatigue and fracture. - Increased vascular calcification and endothelial dysfunction are also - characteristic of arterial aging. These changes lead to increased pulse wave - velocity, especially along central elastic arteries, and increases in systolic - blood pressure and pulse pressure. Vascular aging is accelerated by coexisting - cardiovascular risk factors, such as hypertension, metabolic syndrome and - diabetes. Vascular aging is an independent risk factor for cardiovascular - disease, from atherosclerosis to target organ damage, including coronary artery - disease, stroke and heart failure. Various strategies, especially controlling - hypertension, show benefit in preventing, delaying or attenuating vascular aging. -FAU - Lee, Hae-Young -AU - Lee HY -AD - Department of Internal Medicine, Seoul National University College of Medicine, - Seoul, Korea. -FAU - Oh, Byung-Hee -AU - Oh BH -LA - eng -PT - Journal Article -PT - Review -DEP - 20101015 -PL - Japan -TA - Circ J -JT - Circulation journal : official journal of the Japanese Circulation Society -JID - 101137683 -SB - IM -MH - Age Factors -MH - Aging/*pathology -MH - Animals -MH - Arteries/*pathology/physiopathology -MH - Cardiovascular Diseases/*etiology/pathology/physiopathology/therapy -MH - Elasticity -MH - Hemodynamics -MH - Humans -MH - Risk Factors -MH - Sex Factors -EDAT- 2010/10/22 06:00 -MHDA- 2010/12/14 06:00 -CRDT- 2010/10/22 06:00 -PHST- 2010/10/22 06:00 [entrez] -PHST- 2010/10/22 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -AID - JST.JSTAGE/circj/CJ-10-0910 [pii] -AID - 10.1253/circj.cj-10-0910 [doi] -PST - ppublish -SO - Circ J. 2010 Nov;74(11):2257-62. doi: 10.1253/circj.cj-10-0910. Epub 2010 Oct 15. - -PMID- 21382377 -OWN - NLM -STAT- MEDLINE -DCOM- 20110926 -LR - 20211203 -IS - 1095-8584 (Electronic) -IS - 0022-2828 (Linking) -VI - 50 -IP - 6 -DP - 2011 Jun -TI - The in-situ pig heart with regional ischemia/reperfusion - ready for translation. -PG - 951-63 -LID - 10.1016/j.yjmcc.2011.02.016 [doi] -AB - The pig heart in situ with regional myocardial ischemia and reperfusion is of - unique translational value. Cardiac size, heart rate and blood pressure are - similar to those in humans. The temporal and spatial development of myocardial - infarction resembles that seen in humans. Technically, the pig heart permits - precise control of coronary blood flow during ischemia and reperfusion, includes - an intra-individual remote control zone for comparison, and permits the - sequential sampling of microdialysates and biopsies for further biochemical, - molecular and morphological analyses. Conceptually, all cardioprotective - phenomena, including hibernation, ischemic preconditioning, ischemic - postconditioning, and remote conditioning, have been demonstrated in pig hearts. - The cardioprotective signalling is in part similar, but in part also different - from that in rodent hearts. -CI - Copyright © 2011 Elsevier Ltd. All rights reserved. -FAU - Heusch, Gerd -AU - Heusch G -AD - Institut für Pathophysiologie, Universitätsklinikum Essen, Germany. - gerd.heusch@uk-essen.de -FAU - Skyschally, Andreas -AU - Skyschally A -FAU - Schulz, Rainer -AU - Schulz R -LA - eng -PT - Journal Article -PT - Review -DEP - 20110305 -PL - England -TA - J Mol Cell Cardiol -JT - Journal of molecular and cellular cardiology -JID - 0262322 -SB - IM -MH - Animals -MH - Disease Models, Animal -MH - Humans -MH - *Ischemic Preconditioning, Myocardial/instrumentation/methods -MH - Myocardial Infarction/blood/pathology/physiopathology -MH - *Myocardial Reperfusion/instrumentation/methods -MH - Myocardial Reperfusion Injury/blood/pathology/physiopathology/prevention & - control -MH - Signal Transduction/physiology -MH - Swine -MH - *Translational Research, Biomedical -EDAT- 2011/03/09 06:00 -MHDA- 2011/09/29 06:00 -CRDT- 2011/03/09 06:00 -PHST- 2011/01/10 00:00 [received] -PHST- 2011/02/22 00:00 [revised] -PHST- 2011/02/23 00:00 [accepted] -PHST- 2011/03/09 06:00 [entrez] -PHST- 2011/03/09 06:00 [pubmed] -PHST- 2011/09/29 06:00 [medline] -AID - S0022-2828(11)00093-9 [pii] -AID - 10.1016/j.yjmcc.2011.02.016 [doi] -PST - ppublish -SO - J Mol Cell Cardiol. 2011 Jun;50(6):951-63. doi: 10.1016/j.yjmcc.2011.02.016. Epub - 2011 Mar 5. - -PMID- 16479961 -OWN - NLM -STAT- MEDLINE -DCOM- 20060330 -LR - 20151119 -IS - 0003-9683 (Print) -IS - 0003-9683 (Linking) -VI - 99 Spec No 1 -IP - 1 -DP - 2006 Jan -TI - [The best of nuclear cardiology and MRI in 2005]. -PG - 29-33 -AB - The literature concerning nuclear cardiology and cardiac MRI has been - particularly rich in the fields of diagnosis, prognosis and therapeutic - evaluation of coronary artery disease and cardiac failure. Almost 18 million - 'conventional' myocardial scintigraphies (SPECT-single photon emission - tomography, or TEM: tomography by monophotonic emission in French) are routinely - performed worldwide each year. Nuclear cardiology represents the 3rd scientific - domain of application for scintigraphy, after oncology and neurology. The advent - of new conventional gamma cameras and PET (positron emission tomography) combined - with CT will allow considerable improvement in the quality of investigation in - obese or tri-truncal patients and women. We will limit ourselves to original - clinical studies, based on scintigraphical techniques or magnetic resonance - imaging, applied to the classic cardiological themes: myocardial infarction and - ischaemia, cardiomyopathy and cardiac failure. We will also consider the new - directions in nuclear cardiology regarding a new tracer and some innovative - technology: rubidium-82 and TEP-CT. -FAU - Agostini, D -AU - Agostini D -AD - Pô1e d'imagerie médicale, CHU Côte de Nacre, 14000 Caen. agostini-d@chu-caen.fr -FAU - Slama, M -AU - Slama M -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - L'essentiel de 2005 en cardiologie nucléaire et IRM. -PL - France -TA - Arch Mal Coeur Vaiss -JT - Archives des maladies du coeur et des vaisseaux -JID - 0406011 -RN - 0 (Contrast Media) -RN - 0 (Radiopharmaceuticals) -RN - MLT4718TJW (Rubidium) -SB - IM -MH - Contrast Media -MH - Heart Failure/*pathology/therapy -MH - Humans -MH - *Magnetic Resonance Imaging -MH - Myocardial Ischemia/*pathology/therapy -MH - Publishing/trends -MH - Radiopharmaceuticals -MH - Rubidium -MH - *Tomography, Emission-Computed -RF - 34 -EDAT- 2006/02/17 09:00 -MHDA- 2006/03/31 09:00 -CRDT- 2006/02/17 09:00 -PHST- 2006/02/17 09:00 [pubmed] -PHST- 2006/03/31 09:00 [medline] -PHST- 2006/02/17 09:00 [entrez] -PST - ppublish -SO - Arch Mal Coeur Vaiss. 2006 Jan;99 Spec No 1(1):29-33. - -PMID- 20447567 -OWN - NLM -STAT- MEDLINE -DCOM- 20100812 -LR - 20250529 -IS - 1873-2615 (Electronic) -IS - 1050-1738 (Print) -IS - 1050-1738 (Linking) -VI - 19 -IP - 8 -DP - 2009 Nov -TI - Neuronal nitric oxide synthase and human vascular regulation. -PG - 256-62 -LID - 10.1016/j.tcm.2010.02.007 [doi] -AB - Vascular blood flow and its distribution among different vascular beds are - regulated by changes in microvascular tone. Nitric oxide (NO) plays a key role in - the local paracrine regulation of vessel tone both under resting conditions and - when blood flow increases in response to agonist stimulation or increased shear - stress. The conventional notion that endothelial NO synthase (eNOS)-derived NO is - largely responsible for both effects has been challenged by first-in-human - studies with a selective inhibitor of neuronal NOS (nNOS), - S-methyl-l-thiocitrulline (SMTC). These studies reveal that SMTC causes a - reduction in basal blood flow in the normal human forearm and coronary - circulations (that is reversed by l-arginine), without affecting the - eNOS-mediated vasodilatation elicited by acetylcholine, substance P, or increased - shear stress. S-methyl-l-thiocitrulline also inhibits mental stress-induced - vasodilatation. These results are consistent with a significant body of - experimental studies suggesting that nNOS plays an important role in the local - regulation of vessel tone in other species, independent of the effects of - nNOS-derived NO in the central nervous system. These emerging data suggest that - eNOS and nNOS have distinct roles in the physiologic local regulation of human - microvascular tone in vivo and pave the way for further detailed investigation of - the relative contribution of nNOS and eNOS in vascular regulation in human - disease. -CI - Copyright 2009 Elsevier Inc. All rights reserved. -FAU - Melikian, Narbeh -AU - Melikian N -AD - King's College London British Heart Foundation Centre of Excellence, - Cardiovascular Division, London, United Kingdom. -FAU - Seddon, Michael D -AU - Seddon MD -FAU - Casadei, Barbara -AU - Casadei B -FAU - Chowienczyk, Philip J -AU - Chowienczyk PJ -FAU - Shah, Ajay M -AU - Shah AM -LA - eng -GR - FS/09/062/27958/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Trends Cardiovasc Med -JT - Trends in cardiovascular medicine -JID - 9108337 -RN - 0 (Enzyme Inhibitors) -RN - 29VT07BGDA (Citrulline) -RN - 31C4KY9ESH (Nitric Oxide) -RN - EC 1.14.13.39 (NOS1 protein, human) -RN - EC 1.14.13.39 (NOS3 protein, human) -RN - EC 1.14.13.39 (Nitric Oxide Synthase Type I) -RN - EC 1.14.13.39 (Nitric Oxide Synthase Type III) -RN - GYV9AM2QAG (Thiourea) -RN - M790X706JV (S-methylthiocitrulline) -SB - IM -MH - Animals -MH - Citrulline/analogs & derivatives/pharmacology -MH - Coronary Vessels/drug effects/*enzymology -MH - Enzyme Inhibitors/pharmacology -MH - Forearm/*blood supply -MH - Humans -MH - *Microcirculation/drug effects -MH - Microvessels/enzymology/physiopathology -MH - Nitric Oxide/*metabolism -MH - Nitric Oxide Synthase Type I/antagonists & inhibitors/*metabolism -MH - Nitric Oxide Synthase Type III/metabolism -MH - Stress, Psychological/physiopathology -MH - Thiourea/analogs & derivatives/pharmacology -MH - *Vasodilation/drug effects -PMC - PMC2984617 -EDAT- 2010/05/08 06:00 -MHDA- 2010/08/13 06:00 -PMCR- 2009/11/01 -CRDT- 2010/05/08 06:00 -PHST- 2010/05/08 06:00 [entrez] -PHST- 2010/05/08 06:00 [pubmed] -PHST- 2010/08/13 06:00 [medline] -PHST- 2009/11/01 00:00 [pmc-release] -AID - S1050-1738(10)00025-3 [pii] -AID - 10.1016/j.tcm.2010.02.007 [doi] -PST - ppublish -SO - Trends Cardiovasc Med. 2009 Nov;19(8):256-62. doi: 10.1016/j.tcm.2010.02.007. - -PMID- 24224148 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20211021 -IS - 2234-8646 (Print) -IS - 2234-8840 (Electronic) -IS - 2234-8840 (Linking) -VI - 16 -IP - 3 -DP - 2013 Sep -TI - Polyunsaturated Fatty acids in children. -PG - 153-61 -LID - 10.5223/pghn.2013.16.3.153 [doi] -AB - Polyunsaturated fatty acids (PUFAs) are the major components of brain and retina, - and are the essential fatty acids with important physiologically active - functions. Thus, PUFAs should be provided to children, and are very important in - the brain growth and development for fetuses, newborn infants, and children. - Omega-3 fatty acids decrease coronary artery disease and improve blood flow. - PUFAs have been known to have anti-inflammatory action and improved the chronic - inflammation such as auto-immune diseases or degenerative neurologic diseases. - PUFAs are used for metabolic syndrome related with obesity or diabetes. However, - there are several considerations related with intake of PUFAs. Obsession with the - intake of unsaturated fatty acids could bring about the shortage of essential - fatty acids that are crucial for our body, weaken the immune system, and increase - the risk of heart disease, arrhythmia, and stroke. In this review, we discuss - types, physiologic mechanism of action of PUFAs, intake of PUFAs for children, - recommended intake of PUFAs, and considerations for the intake of PUFAs. -FAU - Lee, Ji-Hyuk -AU - Lee JH -AD - Department of Pediatrics, College of Medicine and Medical Research Institute, - Chungbuk National University, Cheongju, Korea. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130930 -PL - Korea (South) -TA - Pediatr Gastroenterol Hepatol Nutr -JT - Pediatric gastroenterology, hepatology & nutrition -JID - 101590471 -PMC - PMC3819697 -OTO - NOTNLM -OT - Child -OT - Fatty acid -OT - Omega-3 -OT - Omega-6 -OT - Unsaturaed -EDAT- 2013/11/14 06:00 -MHDA- 2013/11/14 06:01 -PMCR- 2013/09/01 -CRDT- 2013/11/14 06:00 -PHST- 2013/08/17 00:00 [received] -PHST- 2013/08/25 00:00 [accepted] -PHST- 2013/11/14 06:00 [entrez] -PHST- 2013/11/14 06:00 [pubmed] -PHST- 2013/11/14 06:01 [medline] -PHST- 2013/09/01 00:00 [pmc-release] -AID - 10.5223/pghn.2013.16.3.153 [doi] -PST - ppublish -SO - Pediatr Gastroenterol Hepatol Nutr. 2013 Sep;16(3):153-61. doi: - 10.5223/pghn.2013.16.3.153. Epub 2013 Sep 30. - -PMID- 22218112 -OWN - NLM -STAT- MEDLINE -DCOM- 20120509 -LR - 20121108 -IS - 1735-8604 (Electronic) -IS - 1735-8582 (Linking) -VI - 6 -IP - 1 -DP - 2012 Jan -TI - Risk factors profile and cardiovascular events in solid organ transplant - recipients. -PG - 9-13 -AB - By advances in surgical techniques, success in prevention and treatment of - transplant-related infections, and introduction of new immunosuppressive drugs, - the patient and graft survival rates in solid organ transplant recipients has - steadily and remarkably improved. It has been shown that the longer the - transplant patients survival rate, the more saturation with cardiovascular risk - factors and the greater risk of cardiovascular mortality. Currently, - cardiovascular disease is the primary cause of death after kidney transplantation - and is among the three most common causes of death after heart and liver - transplantation. Over the past decades, because of risk factor reduction, - mortality from coronary artery disease has substantially decreased in the general - population. Recent studies suggest that risk factors reduction also significantly - decreases cardiovascular events and deaths in solid organ transplant recipients. -FAU - Ghods, Ahad J -AU - Ghods AJ -AD - Division of Nephrology and Transplantation, Hasheminejad Kidney Hospital, Tehran - University of Medical Sciences, Tehran, Iran. ahad.ghods@gmail.com -LA - eng -PT - Journal Article -PT - Review -TA - Iran J Kidney Dis -JT - Iranian journal of kidney diseases -JID - 101316967 -SB - IM -CIN - Iran J Kidney Dis. 2012 May;6(3):225-6. PMID: 22555491 -CIN - Iran J Kidney Dis. 2012 Sep;6(5):390-1. PMID: 22976268 -MH - Cardiovascular Diseases/*etiology/*mortality -MH - Humans -MH - Kidney Transplantation/*adverse effects -MH - Risk Factors -EDAT- 2012/01/06 06:00 -MHDA- 2012/05/10 06:00 -CRDT- 2012/01/06 06:00 -PHST- 2011/08/17 00:00 [received] -PHST- 2011/08/17 00:00 [accepted] -PHST- 2012/01/06 06:00 [entrez] -PHST- 2012/01/06 06:00 [pubmed] -PHST- 2012/05/10 06:00 [medline] -AID - 618/362 [pii] -PST - ppublish -SO - Iran J Kidney Dis. 2012 Jan;6(1):9-13. - -PMID- 21181320 -OWN - NLM -STAT- MEDLINE -DCOM- 20110628 -LR - 20231105 -IS - 1937-5395 (Electronic) -IS - 1937-5387 (Print) -IS - 1937-5387 (Linking) -VI - 4 -IP - 2 -DP - 2011 Apr -TI - Cell therapy for cardiovascular disease: a comparison of methods of delivery. -PG - 177-81 -LID - 10.1007/s12265-010-9253-z [doi] -AB - The field of myocardial regeneration utilizing novel cell-based therapies, gene - transfer, and growth factors may prove to play an important role in the future - management of ischemic heart disease and cardiomyopathy. Phases I and II clinical - trials have been published for a variety of biologics utilizing four methods of - delivery: systemic infusion, intracoronary infusion, transvenous coronary sinus, - and intramyocardial. This review discusses the advantages and disadvantages of - the delivery approaches above. -FAU - Dib, Nabil -AU - Dib N -AD - Mercy Gilbert and Chandler Regional Medical Centers, 3555 S. Val Vista Dr., - Gilbert, AZ 85297, USA. ndib@heartsciencescenter.com -FAU - Khawaja, Harris -AU - Khawaja H -FAU - Varner, Samantha -AU - Varner S -FAU - McCarthy, Megan -AU - McCarthy M -FAU - Campbell, Ann -AU - Campbell A -LA - eng -PT - Journal Article -PT - Review -DEP - 20101223 -PL - United States -TA - J Cardiovasc Transl Res -JT - Journal of cardiovascular translational research -JID - 101468585 -SB - IM -MH - Cardiomyopathies/pathology/physiopathology/*surgery -MH - Humans -MH - Infusions, Intravenous -MH - Injections -MH - Myocardial Ischemia/pathology/physiopathology/*surgery -MH - Myocardium/*pathology -MH - Regeneration -MH - Regenerative Medicine/*methods -MH - Stem Cell Transplantation/adverse effects/*methods -MH - Treatment Outcome -PMC - PMC3047684 -EDAT- 2010/12/25 06:00 -MHDA- 2011/06/29 06:00 -PMCR- 2010/12/23 -CRDT- 2010/12/25 06:00 -PHST- 2010/09/27 00:00 [received] -PHST- 2010/11/23 00:00 [accepted] -PHST- 2010/12/25 06:00 [entrez] -PHST- 2010/12/25 06:00 [pubmed] -PHST- 2011/06/29 06:00 [medline] -PHST- 2010/12/23 00:00 [pmc-release] -AID - 9253 [pii] -AID - 10.1007/s12265-010-9253-z [doi] -PST - ppublish -SO - J Cardiovasc Transl Res. 2011 Apr;4(2):177-81. doi: 10.1007/s12265-010-9253-z. - Epub 2010 Dec 23. - -PMID- 16893716 -OWN - NLM -STAT- MEDLINE -DCOM- 20060921 -LR - 20161124 -IS - 0002-9149 (Print) -IS - 0002-9149 (Linking) -VI - 98 -IP - 4 -DP - 2006 Aug 15 -TI - Systematic overview and clinical applications of pacing atrial stress - echocardiography. -PG - 549-56 -AB - Pacing atrial stress echocardiography (PASE) has been studied over the past 3 - decades for the evaluation of myocardial ischemia. Published studies suggest that - PASE may be used as an alternative to exercise or pharmacologic stress imaging. - The recent introduction of improved pacing electrodes, together with use of - accelerated and shortened pacing protocols and improvements in transthoracic - echocardiographic imaging techniques, makes PASE an appealing stress imaging - method. A critical analysis of the diagnostic accuracy of PASE shows equivalence - with other imaging stress modalities. PASE has been found to be highly feasible - and accurate technique that may expedite the diagnosis and risk stratification of - patients with coronary artery disease. This review addresses the history, - hemodynamics, protocols, accuracy, clinical utility, and cost-effectiveness of - PASE as well as elucidating its place among other stress modalities. -FAU - Modi, Shreyas A -AU - Modi SA -AD - Department of Internal Medicine, Division of Cardiology, University of Texas - Medical Branch, Galveston, Texas, USA. -FAU - Siegel, Robert J -AU - Siegel RJ -FAU - Birnbaum, Yochai -AU - Birnbaum Y -FAU - Atar, Shaul -AU - Atar S -LA - eng -PT - Journal Article -PT - Review -DEP - 20060630 -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -SB - IM -MH - Animals -MH - *Cardiac Pacing, Artificial -MH - Echocardiography, Stress/*methods -MH - Heart Atria/diagnostic imaging/*physiopathology -MH - Humans -MH - Myocardial Ischemia/*diagnostic imaging/physiopathology -MH - Prognosis -MH - Reproducibility of Results -RF - 54 -EDAT- 2006/08/09 09:00 -MHDA- 2006/09/22 09:00 -CRDT- 2006/08/09 09:00 -PHST- 2005/10/25 00:00 [received] -PHST- 2006/02/27 00:00 [revised] -PHST- 2006/02/27 00:00 [accepted] -PHST- 2006/08/09 09:00 [pubmed] -PHST- 2006/09/22 09:00 [medline] -PHST- 2006/08/09 09:00 [entrez] -AID - S0002-9149(06)00834-4 [pii] -AID - 10.1016/j.amjcard.2006.02.067 [doi] -PST - ppublish -SO - Am J Cardiol. 2006 Aug 15;98(4):549-56. doi: 10.1016/j.amjcard.2006.02.067. Epub - 2006 Jun 30. - -PMID- 18018393 -OWN - NLM -STAT- MEDLINE -DCOM- 20080227 -LR - 20170214 -IS - 0267-6591 (Print) -IS - 0267-6591 (Linking) -VI - 22 -IP - 3 -DP - 2007 May -TI - Lessons learned on the path to a healthier brain: dispelling the myths and - challenging the hypotheses. -PG - 153-60 -AB - Neurologic dysfunction remains the most significant complication associated with - cardiopulmonary bypass (CPB). The insidious change of cognitive decline has been - perceived as a key factor that has contributed to the shift to percutaneous - intervention for coronary disease. Current neuropsychologic testing provides the - most sensitive means of demonstrating clinically relevant cerebral damage of this - nature. Through extensive experience in randomized clinical trials of over 900 - patients undergoing CPB, our team has addressed several key hypotheses related to - the embolic/ischemic nature of cerebral injury in cardiac surgery, using this - testing. In the first temperature study, patients randomized to hypothermia with - passive re-warming had a lower incidence of neurocognitive deficit when compared - with those patients who were actively re-warmed to 37 degrees. In order to - clarify the role of the hypothermia as opposed to the re-warming process, a - second temperature study was completed. In the hypothermic group, patients were - cooled and maintained at 34 degrees with no active re-warming whereas, in the - normothermic group, the patients were kept at 37 degrees throughout the - perioperative period. No difference in neurocognitive outcome in the two groups - was seen, implying that the benefit seen in the first temperature study was - related not to the hypothermia, but rather to the absence of active re-warming. - In the cardiotomy study, patients were randomized to either a control group in - which their cardiotomy blood was returned unprocessed, or a treatment group in - which this blood was sequestered and processed with centrifugal washing and fat - filtration. No significant difference in neurocognitive outcome was found in - these two groups. On the other hand, there was a significant increase in bleeding - and transfusion requirements in the treatment group. Many of our daily practices - in CPB management are based upon assumptions from observational studies without - sound reference to evidence-based medicine. Our recent studies have challenged - our assumptions related to ischemia and embolic events during CPB. They have also - confirmed that, when high standards in trial design are applied, the results can - have universal implications in terms of our practice. -FAU - Rubens, Fraser D -AU - Rubens FD -AD - Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, - Canada. frubens@ottawaheart.ca -FAU - Nathan, Howard -AU - Nathan H -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Perfusion -JT - Perfusion -JID - 8700166 -SB - IM -MH - Animals -MH - Body Temperature -MH - Brain Ischemia/diagnosis/etiology/*prevention & control -MH - Cardiopulmonary Bypass/*adverse effects/methods -MH - Cerebrovascular Circulation -MH - Cognition Disorders/diagnosis/etiology/*prevention & control -MH - Dogs -MH - Humans -MH - Hypothermia, Induced/*adverse effects/methods -MH - Intraoperative Period -MH - Neuropsychological Tests -MH - Postoperative Complications/*prevention & control -MH - Postoperative Period -MH - Reperfusion Injury/complications/prevention & control -MH - Rewarming/adverse effects/methods/psychology -RF - 68 -EDAT- 2007/11/21 09:00 -MHDA- 2008/02/28 09:00 -CRDT- 2007/11/21 09:00 -PHST- 2007/11/21 09:00 [pubmed] -PHST- 2008/02/28 09:00 [medline] -PHST- 2007/11/21 09:00 [entrez] -AID - 10.1177/0267659107078142 [doi] -PST - ppublish -SO - Perfusion. 2007 May;22(3):153-60. doi: 10.1177/0267659107078142. - -PMID- 19007320 -OWN - NLM -STAT- MEDLINE -DCOM- 20090211 -LR - 20191111 -IS - 1744-7631 (Electronic) -IS - 1472-8222 (Linking) -VI - 12 -IP - 12 -DP - 2008 Dec -TI - Autophagy: a target for therapeutic interventions in myocardial pathophysiology. -PG - 1509-22 -LID - 10.1517/14728220802555554 [doi] -AB - BACKGROUND: Autophagy is a major degradative and highly conserved process in - eukaryotic cells that is activated by stress signals. This self-cannibalisation - is activated as a response to changing environmental conditions, cellular - remodelling during development and differentiation, and maintenance of - homeostasis. OBJECTIVE: To review autophagy regarding its process, molecular - mechanisms and regulation in mammalian cells, and its role in myocardial - pathophysiology. RESULTS/CONCLUSION: Autophagy is a multistep process regulated - by diverse, intracellular and/or extracellular signalling complexes and pathways. - In the heart, normally, autophagy occurs at low basal levels, where it represents - a homeostatic mechanism for the maintenance of cardiac function and morphology. - However, in the diseased heart the functional role of the enhanced autophagy is - unclear and studies have yielded conflicting results. Recently, it was shown that - during myocardial ischemia autophagy promotes survival by maintaining energy - homeostasis. Also, rapamycin was demonstrated to prevent cardiac hypertrophy. In - heart failure, upregulation of autophagy acts as an adaptive response that - protects cells from hemodynamic stress. In addition, sirolimus-eluting stents - have been shown to lower re-stenosis rates in patients with coronary artery - disease after angioplasty. Thus, this mechanism can become a major target for - therapeutic intervention in heart pathophysiology. -FAU - Halapas, Antonis -AU - Halapas A -AD - National and Kapodistrian University of Athens, Medical School, Department of - Experimental Physiology, Goudi-Athens, Greece. -FAU - Armakolas, Athanasios -AU - Armakolas A -FAU - Koutsilieris, Michael -AU - Koutsilieris M -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Opin Ther Targets -JT - Expert opinion on therapeutic targets -JID - 101127833 -SB - IM -MH - Animals -MH - Autophagy/*drug effects -MH - Cardiovascular Diseases/*drug therapy/*physiopathology -MH - Humans -MH - Mice -MH - Rats -MH - Signal Transduction -RF - 120 -EDAT- 2008/11/15 09:00 -MHDA- 2009/02/12 09:00 -CRDT- 2008/11/15 09:00 -PHST- 2008/11/15 09:00 [pubmed] -PHST- 2009/02/12 09:00 [medline] -PHST- 2008/11/15 09:00 [entrez] -AID - 10.1517/14728220802555554 [doi] -PST - ppublish -SO - Expert Opin Ther Targets. 2008 Dec;12(12):1509-22. doi: - 10.1517/14728220802555554. - -PMID- 23357600 -OWN - NLM -STAT- MEDLINE -DCOM- 20130502 -LR - 20161125 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 29 -IP - 3 -DP - 2013 Mar -TI - Imaging of valvular heart disease. -PG - 337-49 -LID - S0828-282X(12)01457-2 [pii] -LID - 10.1016/j.cjca.2012.11.006 [doi] -AB - Imaging plays a fundamental role in the current diagnosis and treatment of - valvular heart disease (VHD) and in the preclinical and clinical research aiming - at the development of novel pharmacologic or interventional therapies. Doppler - echocardiography remains the primary imaging technique for the clinical - management of VHD. However, the multifaceted and complex nature of VHD and the - rapid development of transcatheter valve therapies has led to a spectacular - increase in the use of multimodality imaging in the past decade. The purpose of - this article is to review the current and emerging roles of the different imaging - modalities in the diagnosis and treatment of VHD and to present the new - directions for future research and clinical applications. -CI - Copyright © 2013 Canadian Cardiovascular Society. Published by Elsevier Inc. All - rights reserved. -FAU - Pibarot, Philippe -AU - Pibarot P -AD - Québec Heart and Lung Institute, Department of Medicine, Laval University, - Québec, Québec, Canada. philippe.pibarot@med.ulaval.ca -FAU - Larose, Éric -AU - Larose É -FAU - Dumesnil, Jean -AU - Dumesnil J -LA - eng -GR - MOP-114997/Canadian Institutes of Health Research/Canada -GR - MOP-57745/Canadian Institutes of Health Research/Canada -GR - MOP102737/Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130126 -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Cardiac Imaging Techniques/methods -MH - Coronary Angiography -MH - Diagnostic Imaging/*methods -MH - Echocardiography, Doppler -MH - Echocardiography, Stress -MH - Echocardiography, Three-Dimensional -MH - Heart Valve Diseases/*diagnosis/diagnostic imaging/therapy -MH - Heart Ventricles/diagnostic imaging/pathology -MH - Humans -MH - Magnetic Resonance Imaging -MH - Multidetector Computed Tomography -MH - Practice Guidelines as Topic -MH - Predictive Value of Tests -MH - Sensitivity and Specificity -EDAT- 2013/01/30 06:00 -MHDA- 2013/05/03 06:00 -CRDT- 2013/01/30 06:00 -PHST- 2012/10/01 00:00 [received] -PHST- 2012/11/01 00:00 [revised] -PHST- 2012/11/04 00:00 [accepted] -PHST- 2013/01/30 06:00 [entrez] -PHST- 2013/01/30 06:00 [pubmed] -PHST- 2013/05/03 06:00 [medline] -AID - S0828-282X(12)01457-2 [pii] -AID - 10.1016/j.cjca.2012.11.006 [doi] -PST - ppublish -SO - Can J Cardiol. 2013 Mar;29(3):337-49. doi: 10.1016/j.cjca.2012.11.006. Epub 2013 - Jan 26. - -PMID- 23114270 -OWN - NLM -STAT- MEDLINE -DCOM- 20130423 -LR - 20220317 -IS - 1558-2035 (Electronic) -IS - 1558-2027 (Linking) -VI - 13 -IP - 11 -DP - 2012 Nov -TI - Remote ischemic conditioning: the cardiologist's perspective. -PG - 667-74 -LID - 10.2459/JCM.0b013e328357bff2 [doi] -AB - Early and successful restoration of myocardial reperfusion following an ischemic - event is the most effective strategy to reduce final infarct size and improve - clinical outcome. However, revascularization per se may induce further myocardial - damage by myocardial ischemia-reperfusion injury and worsen clinical outcome. - Therefore, new therapeutic strategies are required to protect the myocardium - against ischemia-reperfusion injury in patients with coronary artery disease. - Remote ischemic conditioning (RIC) by brief nonlethal episodes of ischemia and - reperfusion to an organ or tissue remote from the heart activates innate - cardioprotective mechanisms. The discovery that RIC can be performed - noninvasively using a blood pressure cuff on the upper arm to induce brief - episodes of limb ischemia and reperfusion has facilitated the translation of RIC - into the clinical arena. Whereas some trials have shown contradictory results, - recently published proof-of-concept clinical studies have reported encouraging - results with RIC. Large-scale multicenter clinical trials are needed to establish - the role of RIC in the current clinical practice. At present, the use of RIC in - acute coronary syndromes seems particularly attractive due to its potential - in-ambulance application and apparent dramatic reduction in infarct size in the - patients with the largest infarcts. Cardiac arrest and stroke represent - ischemia-reperfusion disorders where RIC has further potential to improve outcome - beyond rapid revascularization alone. -FAU - Schmidt, Michael R -AU - Schmidt MR -AD - Department of Cardiology, Aarhus University Hospital Skejby, Brendstrupgaardsvej, - Aarhus N, Denmark. -FAU - Sloth, Astrid D -AU - Sloth AD -FAU - Johnsen, Jacob -AU - Johnsen J -FAU - Bøtker, Hans E -AU - Bøtker HE -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Cardiovasc Med (Hagerstown) -JT - Journal of cardiovascular medicine (Hagerstown, Md.) -JID - 101259752 -SB - IM -MH - Heart Arrest/etiology/prevention & control -MH - Humans -MH - Ischemic Postconditioning/*methods -MH - Ischemic Preconditioning/*methods -MH - Myocardial Infarction/etiology/prevention & control -MH - Myocardial Reperfusion/*adverse effects -MH - Myocardial Reperfusion Injury/etiology/*prevention & control -MH - Myocardial Revascularization/*adverse effects -MH - Regional Blood Flow -MH - Stroke/etiology/prevention & control -MH - Tourniquets -MH - Treatment Outcome -MH - Upper Extremity/*blood supply -EDAT- 2012/11/02 06:00 -MHDA- 2013/04/24 06:00 -CRDT- 2012/11/02 06:00 -PHST- 2012/11/02 06:00 [entrez] -PHST- 2012/11/02 06:00 [pubmed] -PHST- 2013/04/24 06:00 [medline] -AID - 10.2459/JCM.0b013e328357bff2 [doi] -PST - ppublish -SO - J Cardiovasc Med (Hagerstown). 2012 Nov;13(11):667-74. doi: - 10.2459/JCM.0b013e328357bff2. - -PMID- 22552173 -OWN - NLM -STAT- MEDLINE -DCOM- 20121207 -LR - 20191210 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 28 -IP - 5 -DP - 2012 Sep-Oct -TI - Pan-Canadian cardiovascular data definitions and quality indicators: a status - update. -PG - 599-601 -LID - S0828-282X(12)00052-9 [pii] -LID - 10.1016/j.cjca.2012.01.024 [doi] -AB - After the 2009 publication of Building a Heart Healthy Canada, the Canadian - Cardiovascular Society was commissioned to address a long-standing information - gap related to the compatibility and comparability of data on the quality of - cardiovascular care in Canada. Through collaboration between the Canadian - Institute for Health Information, the Institute for Clinical Evaluative Sciences, - the Public Health Agency of Canada, and 5 regional cardiovascular registries, 2 - committees were tasked with developing standardized cardiovascular data - definitions and quality indicators. The work culminated in national consensus on - the definitions of 55 patient, disease, and therapeutic variables (core and - optional) to facilitate cardiovascular care comparisons within and across Canada. - Supplemental data definition chapters were then developed on acute coronary - syndrome and coronary angiography/revascularization, with chapters on heart - failure and atrial fibrillation electrophysiology to follow. This foundational - work led to a critical appraisal of cardiac quality indicator development - initiatives via the Appraisal of Guidelines for Research and Evaluation II (AGREE - II) Quality Indicator tool, followed by the development of quality indicator - catalogues on heart failure and atrial fibrillation. These indicators will be - embedded within the clinical practice guidelines of the Canadian Cardiovascular - Society, facilitating national comparisons across Canada on cardiovascular - disease incidence, prevalence, patterns and quality of care, and clinical - outcomes. This methodology-achieving national stakeholder consensus on a - standardized process for the development and selection of cardiovascular quality - indicators-illustrates the capacity to reach agreement by drawing on expertise - and research across diverse organizational mandates and agendas, potentially - contributing to improved cardiovascular care and outcomes for patients. -CI - Copyright © 2012 Canadian Cardiovascular Society. Published by Elsevier Inc. All - rights reserved. -FAU - Johnstone, David E -AU - Johnstone DE -AD - Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, - Canada. david.johnstone@albertahealthservices.ca -FAU - Buller, Christopher E -AU - Buller CE -CN - National Steering Committees on Quality Indicators and Data Definitions, Canadian - Cardiovascular Society -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120501 -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Canada -MH - Cardiovascular Diseases/*prevention & control/therapy -MH - Databases, Factual -MH - Female -MH - Health Promotion/*organization & administration -MH - Health Status -MH - Humans -MH - Male -MH - Outcome Assessment, Health Care -MH - Practice Guidelines as Topic/*standards -MH - Primary Prevention/organization & administration -MH - Quality Indicators, Health Care/*standards -MH - Societies, Medical/standards -EDAT- 2012/05/04 06:00 -MHDA- 2012/12/12 06:00 -CRDT- 2012/05/04 06:00 -PHST- 2011/10/11 00:00 [received] -PHST- 2012/01/24 00:00 [revised] -PHST- 2012/01/24 00:00 [accepted] -PHST- 2012/05/04 06:00 [entrez] -PHST- 2012/05/04 06:00 [pubmed] -PHST- 2012/12/12 06:00 [medline] -AID - S0828-282X(12)00052-9 [pii] -AID - 10.1016/j.cjca.2012.01.024 [doi] -PST - ppublish -SO - Can J Cardiol. 2012 Sep-Oct;28(5):599-601. doi: 10.1016/j.cjca.2012.01.024. Epub - 2012 May 1. - -PMID- 22920717 -OWN - NLM -STAT- MEDLINE -DCOM- 20130408 -LR - 20120827 -IS - 1876-4738 (Electronic) -IS - 0914-5087 (Linking) -VI - 60 -IP - 2 -DP - 2012 Aug -TI - Heart rate as a target of treatment of chronic heart failure. -PG - 86-90 -LID - 10.1016/j.jjcc.2012.06.013 [doi] -AB - Cardiovascular risk of increased heart rate (HR) was first reported in the - Framingham study. Thereafter, the risk of increased HR for mortality has been - extensively studied, suggesting the higher risk in clinical outcomes with - increased HR in the general population and in patients with coronary artery - disease or heart failure (HF). In a long-term follow-up study in Framingham, the - general population in this cohort showed an increase in all-cause mortality by - 14% at every 10 bpm increase in HR. In patients with heart failure, resting HR of - more than 80 bpm could cause myocardial dysfunction which further deteriorates - HF. Downregulation of β-adrenoreptor receptors with suppressed signal - transductions, impaired intracellular Ca homeostasis, and excitation-contraction - coupling may play a role in myocardial dysfunction. These subcellular alterations - are mimicked in the pacing-induced HF in large animals; however, exact mechanisms - of cardiac deterioration by increased HR are not fully understood. β-Blocker - treatment is the most effective therapy for long-term survival of patients with - chronic HF. Meta-analysis of HR reduction and improvement in survival in patients - with chronic HF indicates that HR reduction is more important than the titrated - dose of β-blockers, although the relative importance of HR reduction in - improvement of prognosis is not clear. A recent study in which ivabradine - decreased the hospitalization from HR deterioration in patients with chronic HF, - demonstrated that further HR reduction with optimal treatment for HF is - beneficial for clinical outcomes of the patients. These findings strongly suggest - that HR reduction should be a pivotal target of the treatment in patients with - HF. -CI - Copyright © 2012. Published by Elsevier Ltd. -FAU - Hori, Masatsugu -AU - Hori M -AD - Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan. - hor-ma@mc.pref.osaka.jp -FAU - Okamoto, Hiroshi -AU - Okamoto H -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - J Cardiol -JT - Journal of cardiology -JID - 8804703 -RN - 0 (Adrenergic beta-Antagonists) -SB - IM -MH - Adrenergic beta-Antagonists/*therapeutic use -MH - Animals -MH - Chronic Disease -MH - Disease Progression -MH - Heart Failure/diagnosis/*drug therapy/physiopathology -MH - Heart Rate -MH - Humans -EDAT- 2012/08/28 06:00 -MHDA- 2013/04/09 06:00 -CRDT- 2012/08/28 06:00 -PHST- 2012/06/05 00:00 [received] -PHST- 2012/06/07 00:00 [accepted] -PHST- 2012/08/28 06:00 [entrez] -PHST- 2012/08/28 06:00 [pubmed] -PHST- 2013/04/09 06:00 [medline] -AID - S0914-5087(12)00125-6 [pii] -AID - 10.1016/j.jjcc.2012.06.013 [doi] -PST - ppublish -SO - J Cardiol. 2012 Aug;60(2):86-90. doi: 10.1016/j.jjcc.2012.06.013. - -PMID- 19507576 -OWN - NLM -STAT- MEDLINE -DCOM- 20090707 -LR - 20090610 -IS - 0004-1955 (Print) -IS - 0004-1955 (Linking) -VI - 71 -IP - 2 -DP - 2009 Mar-Apr -TI - [Cardiac lesion in the Churg-Strauss syndrome]. -PG - 29-32 -AB - The Churg-Strauss syndrome is a systemic vasculitis, the manifestations of which - are asthma, eosinophilia, pulmonary infiltrates, poly- and mononeuropathy, - polyserositis. Along with nodular polyarteritis and nonspecific aortoarteritis, - the Churg-Strauss syndrome belongs to a group of systemic vasculitis, in the - clinical picture of which cardiac lesion is recognized as one of the leading - visceral manifestations and may be a common cause of fatal outcomes. In the - Churg-Strauss syndrome, cardiac pathology may be associated with the involvement - of the endocardium, myocardium, and pericardium. The paper describes a case - showing the poor course of the disease in a young female patient in whom the - heart is involved in a pathological process with the development of severe heart - failure, resulting in death. There is a rare concomitance of diffuse myocardial - damage, coronary lesion, and valvular pathology - eosinophilic endocarditis. The - diagnosis has been verified on the basis of the data of clinical and additional - studies and the results of microscopic studies. The data available in the Russian - and foreign literature on cardiac pathology in patients with the Churg-Strauss - syndrome are analyzed. -FAU - Kogan, E A -AU - Kogan EA -FAU - Strizhakov, L A -AU - Strizhakov LA -FAU - Namestnikova, O G -AU - Namestnikova OG -FAU - Krivosheev, O G -AU - Krivosheev OG -FAU - Semenkova, E N -AU - Semenkova EN -LA - rus -PT - Case Reports -PT - English Abstract -PT - Journal Article -PT - Review -PL - Russia (Federation) -TA - Arkh Patol -JT - Arkhiv patologii -JID - 0370604 -SB - IM -MH - Adult -MH - Churg-Strauss Syndrome/blood/*complications/*pathology -MH - Fatal Outcome -MH - Female -MH - Heart Failure/blood/*etiology/*pathology -MH - Humans -MH - Myocardium/*pathology -RF - 19 -EDAT- 2009/06/11 09:00 -MHDA- 2009/07/08 09:00 -CRDT- 2009/06/11 09:00 -PHST- 2009/06/11 09:00 [entrez] -PHST- 2009/06/11 09:00 [pubmed] -PHST- 2009/07/08 09:00 [medline] -PST - ppublish -SO - Arkh Patol. 2009 Mar-Apr;71(2):29-32. - -PMID- 19737164 -OWN - NLM -STAT- MEDLINE -DCOM- 20100929 -LR - 20250529 -IS - 1751-7117 (Electronic) -IS - 0889-7204 (Print) -IS - 0889-7204 (Linking) -VI - 24 -IP - 3 -DP - 2009 Sep -TI - Cardiovascular nursing on human genomics: what do cardiovascular nurses need to - know about congestive heart failure? -PG - 80-5 -LID - 10.1111/j.1751-7117.2009.00039.x [doi] -AB - This paper presents the main causes of heart failure (HF) and an update on the - genetics studies on each cause. The review includes a delineation of the etiology - and fundamental pathophysiology of HF and provides rational for treatment for the - patient and family. Various cardiomyopathies are discussed, including primary - cardiomyopathies, mixed cardiomyopathies, cardiomyopathies that involve altered - cardiac muscle along with generalized multiorgan disorders, and various - cardiovascular conditions, such as coronary artery disease (ischemic - cardiomyopathy) and hypertension (hypertensive cardiomyopathy). A brief review of - pharmacogenetics and HF is presented. The application of the genetic components - of cardiomyopathy and pharmacogenetics is included to enhance cardiovascular - nursing care. -FAU - Frazier, Lorraine -AU - Frazier L -AD - The University of Texas Health Science Center School of Nursing at Houston, 6901 - Bertner, Houston, TX 77030, USA. lorraine.frazier@uth.tmc.edu -FAU - Wung, Shu-Fen -AU - Wung SF -FAU - Sparks, Elizabeth -AU - Sparks E -FAU - Eastwood, Cathy -AU - Eastwood C -LA - eng -GR - R01 NR010235/NR/NINR NIH HHS/United States -GR - 1R01 NR 010235-01A1/NR/NINR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - Prog Cardiovasc Nurs -JT - Progress in cardiovascular nursing -JID - 8704064 -SB - IM -MH - Cardiomyopathies/genetics/nursing/physiopathology -MH - Genetic Testing -MH - *Genome, Human -MH - Heart Failure/genetics/*nursing/physiopathology -MH - Humans -MH - Nurse's Role -MH - Pharmacogenetics -MH - Risk Factors -PMC - PMC2749227 -MID - NIHMS144259 -EDAT- 2009/09/10 06:00 -MHDA- 2010/09/30 06:00 -PMCR- 2010/09/01 -CRDT- 2009/09/10 06:00 -PHST- 2009/09/10 06:00 [entrez] -PHST- 2009/09/10 06:00 [pubmed] -PHST- 2010/09/30 06:00 [medline] -PHST- 2010/09/01 00:00 [pmc-release] -AID - PCV39 [pii] -AID - 10.1111/j.1751-7117.2009.00039.x [doi] -PST - ppublish -SO - Prog Cardiovasc Nurs. 2009 Sep;24(3):80-5. doi: 10.1111/j.1751-7117.2009.00039.x. - -PMID- 18080705 -OWN - NLM -STAT- MEDLINE -DCOM- 20080722 -LR - 20211020 -IS - 0364-2313 (Print) -IS - 0364-2313 (Linking) -VI - 32 -IP - 3 -DP - 2008 Mar -TI - Current status of the surgical treatment of atrial fibrillation. -PG - 346-9 -AB - Atrial fibrillation (AF) affects several million patients worldwide and is - associated with a number of heart conditions, particularly coronary artery - disease, rheumatic heart disease, hypertension, and congestive heart failure. The - treatment of AF and its complications is quite costly. Atrial fibrillation - usually results from multiple macro-re-entrant circuits in the left atrium. Very - frequently, particularly in association with mitral valve disease, these circuits - arise from the area of the junction of the pulmonary venous endothelium and the - left atrial endocardium. Pharmacological therapy is at best 50% effective. - Therapeutic options for AF include antiarrhythmic drugs, cardioversion, - atrioventricular (A-V) node block, pacemaker insertion, and ablative surgery. In - 1987, Cox developed an effective surgical procedure to achieve ablation. Current - ablative procedures include the classic cut-and-sew Maze operation or a - modification of it, namely through catheter ablation, namely, cryoablation, - radiofrequency ablation (dry or irrigated), and other forms of ablation (e.g., - laser, microwave). These procedures will be described, along with the - indications, advantages and disadvantages of each. Special emphasis on the - alternative means to cutting and sewing to achieve appropriate effective atrial - scars will be stressed, and our experience with these approaches in 50 patients - with AF and associated cardiac lesions and their outcomes is presented. -FAU - Geha, Alexander S -AU - Geha AS -AD - Division of Cardiothoracic Surgery, The University of Illinois Medical Center at - Chicago, 840 S. Wood Street, CSB 417 (MC 958), Chicago, Illinois 60612, United - States. Ageha@uic.edu -FAU - Abdelhady, Khaled -AU - Abdelhady K -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - World J Surg -JT - World journal of surgery -JID - 7704052 -SB - IM -MH - Aged -MH - Atrial Fibrillation/*surgery -MH - Cardiac Surgical Procedures/instrumentation/*methods -MH - Catheter Ablation -MH - Cryotherapy -MH - Electrophysiologic Techniques, Cardiac -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -RF - 15 -EDAT- 2007/12/18 09:00 -MHDA- 2008/07/23 09:00 -CRDT- 2007/12/18 09:00 -PHST- 2007/12/18 09:00 [pubmed] -PHST- 2008/07/23 09:00 [medline] -PHST- 2007/12/18 09:00 [entrez] -AID - 10.1007/s00268-007-9380-0 [doi] -PST - ppublish -SO - World J Surg. 2008 Mar;32(3):346-9. doi: 10.1007/s00268-007-9380-0. - -PMID- 16824612 -OWN - NLM -STAT- MEDLINE -DCOM- 20070227 -LR - 20131121 -IS - 0163-7258 (Print) -IS - 0163-7258 (Linking) -VI - 112 -IP - 2 -DP - 2006 Nov -TI - Cytochrome P450 enzymes: central players in cardiovascular health and disease. -PG - 564-87 -AB - Cardiovascular disease (CVD) is a human health crisis that remains the leading - cause of death worldwide. The cytochrome P450 (CYP) class of enzymes are key - metabolizers of both xenobiotics and endobiotics. Many CYP enzyme families have - been identified in the heart, endothelium and smooth muscle of blood vessels. - Furthermore, mounting evidence points to the role of endogenous CYP metabolites, - such as epoxyeicosatrienoic acids (EETs), hydroxyeicosatetraenoic acids (HETEs), - prostacyclin (PGI(2)), aldosterone, and sex hormones, in the maintenance of - cardiovascular health. Emerging science and the development of genetic screening - have provided us with information on the differences in CYP expression among - populations and groups of individuals. With this information, a link between CYP - expression and activity and CVD, such as hypertension, coronary artery disease - (CAD), myocardial infarction, heart failure, stroke, and cardiomyopathy and - arrhythmias, has been established. In fact many currently used therapeutic - modalities in CVD owe their therapeutic efficacy to their effect on CYP - metabolites. Thus, the evidence for the involvement of CYP in CVD is numerous. - Concentrating on treatment modalities that target the CYP pathway makes ethical - sense for the affected individuals and decreases the socioeconomic burden of this - disease. However, more research is needed to allow the integration of this - information into a clinical setting. -FAU - Elbekai, Reem H -AU - Elbekai RH -AD - Faculty of Pharmacy and Pharmaceutical Sciences, 3126 Dentistry/Pharmacy Centre, - University of Alberta, Edmonton, Alberta, Canada T6G 2N8. -FAU - El-Kadi, Ayman O S -AU - El-Kadi AO -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20060707 -PL - England -TA - Pharmacol Ther -JT - Pharmacology & therapeutics -JID - 7905840 -RN - 0 (Receptors, Thromboxane) -RN - 27YG812J1I (Arachidonic Acid) -RN - 9035-51-2 (Cytochrome P-450 Enzyme System) -RN - DCR9Z582X0 (Epoprostenol) -SB - IM -MH - Arachidonic Acid -MH - Cardiomegaly -MH - Cardiovascular Diseases/*enzymology/genetics -MH - Cardiovascular System/*enzymology -MH - Cytochrome P-450 Enzyme System/*metabolism -MH - Epoprostenol -MH - Heart Failure -MH - Humans -MH - Polymorphism, Genetic -MH - Receptors, Thromboxane -RF - 317 -EDAT- 2006/07/11 09:00 -MHDA- 2007/02/28 09:00 -CRDT- 2006/07/11 09:00 -PHST- 2005/05/17 00:00 [received] -PHST- 2005/05/17 00:00 [accepted] -PHST- 2006/07/11 09:00 [pubmed] -PHST- 2007/02/28 09:00 [medline] -PHST- 2006/07/11 09:00 [entrez] -AID - S0163-7258(06)00089-1 [pii] -AID - 10.1016/j.pharmthera.2005.05.011 [doi] -PST - ppublish -SO - Pharmacol Ther. 2006 Nov;112(2):564-87. doi: 10.1016/j.pharmthera.2005.05.011. - Epub 2006 Jul 7. - -PMID- 17700384 -OWN - NLM -STAT- MEDLINE -DCOM- 20070906 -LR - 20141120 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 15 -IP - 5 -DP - 2007 Sep-Oct -TI - Importance of medication adherence in cardiovascular disease and the value of - once-daily treatment regimens. -PG - 257-63 -AB - An estimated 71 million individuals in the United States are currently diagnosed - with cardiovascular disease (CVD). If untreated, CVD conditions such as systemic - hypertension, coronary artery disease, and heart failure will have potentially - serious and often fatal outcomes. Numerous clinical trials have established a - variety of evidence-based medications that are efficacious in the treatment of - CVD. These drugs will be ineffective, however, if patients have trouble adhering - to their prescribed regimens. In patients with hypertension or heart failure, or - in those who have suffered a myocardial infarction, poor adherence to therapies - has been linked to a variety of problems, including poor blood pressure control, - rehospitalization, and increased healthcare resource utilization. Both the - asymptomatic nature of some forms of CVD and the high pill burden associated with - certain therapies have been linked to poor adherence. Reducing pill burden - through the use of once-daily formulations has proven valuable in improving - adherence to evidence-based therapies. This review will discuss the impact of - adherence to prescribed therapies for CVD, outline common barriers to adherence, - and demonstrate the value of once-daily dosing regimens for improved patient - adherence. -FAU - Frishman, William H -AU - Frishman WH -AD - Department of Medicine, New York Medical College/Westchester Medical Center, - Valhalla, New York 10595, USA. william_frishman@nymc.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Antihypertensive Agents) -RN - 0 (Delayed-Action Preparations) -RN - 0 (Tablets) -SB - IM -MH - Antihypertensive Agents/administration & dosage -MH - Cardiovascular Diseases/*drug therapy -MH - Chronic Disease -MH - Delayed-Action Preparations -MH - Drug Administration Schedule -MH - Drug Therapy, Combination -MH - Heart Failure/drug therapy/prevention & control -MH - Humans -MH - Hypertension/drug therapy/prevention & control -MH - Myocardial Infarction/drug therapy/prevention & control -MH - *Patient Compliance/psychology/statistics & numerical data -MH - Patient Readmission/statistics & numerical data -MH - Secondary Prevention -MH - Tablets -MH - Treatment Refusal/psychology/*statistics & numerical data -RF - 51 -EDAT- 2007/08/19 09:00 -MHDA- 2007/09/07 09:00 -CRDT- 2007/08/19 09:00 -PHST- 2007/08/19 09:00 [pubmed] -PHST- 2007/09/07 09:00 [medline] -PHST- 2007/08/19 09:00 [entrez] -AID - 00045415-200709000-00005 [pii] -AID - 10.1097/CRD.0b013e3180cabbe7 [doi] -PST - ppublish -SO - Cardiol Rev. 2007 Sep-Oct;15(5):257-63. doi: 10.1097/CRD.0b013e3180cabbe7. - -PMID- 17575806 -OWN - NLM -STAT- MEDLINE -DCOM- 20070711 -LR - 20151119 -IS - 0340-9937 (Print) -IS - 0340-9937 (Linking) -VI - 31 Suppl 3 -DP - 2006 Dec -TI - Omega-3 fatty acids and sudden arrhythmic death. -PG - 59-64 -AB - Cardiovascular disease is the leading cause of death in developed countries. In - Canada, in 1999, cardiovascular disease was responsible for 36% of all deaths. - Ischemic heart disease accounts for the greatest percentage of these deaths (20% - of all deaths), half of which are due to the acute effects of myocardial - infarction. The other half are related to the late manifestations and - complications of myocardial infarction. Once coronary arteriosclerosis has - reached the point where it results in myocardial infarction, two main - complications can ensue, loss of myocardial function and disturbance of cardiac - rhythm. Progressive loss of myocardial pump function results in the syndrome of - congestive heart failure. Abnormalities of the heart rhythm result in ventricular - fibrillation, which is the direct cause of sudden death. Congestive heart failure - rates have been easy to track because of the frequent need for hospitalization - and we know from analysis of administrative databases that the annual rate of - death from heart failure is about 2.5% in Canada. Sudden death, however most - often occurs at home and without warning, making it much more difficult to - quantitate its impact. However, the most conservative estimates suggest that no - less than 25% of deaths in patients with a diagnosis of ischemic heart disease - are due to ventricular fibrillation. -FAU - Connolly, Stuart J -AU - Connolly SJ -AD - Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada. -FAU - Healey, Jeffrey S -AU - Healey JS -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -RN - 0 (Dietary Fats, Unsaturated) -RN - 0 (Fatty Acids, Omega-3) -SB - IM -MH - Arrhythmias, Cardiac/*diet therapy/*mortality -MH - Canada/epidemiology -MH - Comorbidity -MH - Death, Sudden, Cardiac/*epidemiology/*prevention & control -MH - Dietary Fats, Unsaturated/*therapeutic use -MH - Fatty Acids, Omega-3/*therapeutic use -MH - Humans -MH - Practice Guidelines as Topic -MH - Practice Patterns, Physicians' -MH - Survival Rate -MH - Treatment Outcome -RF - 31 -EDAT- 2007/06/20 09:00 -MHDA- 2007/07/12 09:00 -CRDT- 2007/06/20 09:00 -PHST- 2007/06/20 09:00 [pubmed] -PHST- 2007/07/12 09:00 [medline] -PHST- 2007/06/20 09:00 [entrez] -PST - ppublish -SO - Herz. 2006 Dec;31 Suppl 3:59-64. - -PMID- 20559783 -OWN - NLM -STAT- MEDLINE -DCOM- 20101116 -LR - 20250529 -IS - 1937-5395 (Electronic) -IS - 1937-5387 (Print) -IS - 1937-5387 (Linking) -VI - 3 -IP - 4 -DP - 2010 Aug -TI - Mitochondrial pruning by Nix and BNip3: an essential function for - cardiac-expressed death factors. -PG - 374-83 -LID - 10.1007/s12265-010-9174-x [doi] -AB - Programmed cardiac myocyte death via the intrinsic, or mitochondrial, pathway is - a mechanism of pathological ventricular remodeling after myocardial infarction - and during chronic pressure overload hypertrophy. Transcriptional upregulation of - the closely related proapoptotic Bcl2 family members BNip3 in ischemic myocardium - and Nix in hypertrophied myocardium suggested a molecular mechanism by which - programmed cell death can be initiated by cardiac stress and lead to dilated - cardiomyopathy. Studies using transgenic and gene knockout mice subsequently - demonstrated that expression of BNip3 and Nix is both sufficient for - cardiomyopathy development and necessary for cardiac remodeling after reversible - coronary occlusion and transverse aortic banding, respectively. Here, these data - are reviewed in the context of recent findings showing that Nix not only - stimulates cardiomyocyte apoptosis but also induces mitochondrial autophagy - (mitophagy) and indirectly activates the mitochondrial permeability transition - pore, causing cell necrosis. New findings are presented suggesting that Nix and - BNip3 have an essential function, "mitochondrial pruning," that restrains - mitochondrial proliferation in cardiomyocytes and without which an age-dependent - mitochondrial cardiomyopathy develops. -FAU - Dorn, Gerald W 2nd -AU - Dorn GW 2nd -AD - Center for Pharmacogenomics, Department of Internal Medicine, Washington - University School of Medicine, St. Louis, MO, USA. gdorn@dom.wustl.edu -LA - eng -GR - R01 HL059888/HL/NHLBI NIH HHS/United States -GR - HL059888/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20100316 -PL - United States -TA - J Cardiovasc Transl Res -JT - Journal of cardiovascular translational research -JID - 101468585 -RN - 0 (BNip3 protein, mouse) -RN - 0 (Membrane Proteins) -RN - 0 (Mitochondrial Proteins) -RN - 0 (Nix protein, mouse) -SB - IM -MH - Animals -MH - Apoptosis -MH - Autophagy -MH - Disease Models, Animal -MH - Heart Failure/*metabolism/pathology/physiopathology -MH - Membrane Proteins/genetics/*metabolism -MH - Mice -MH - Mitochondria, Heart/genetics/*metabolism -MH - Mitochondrial Proteins/genetics/*metabolism -MH - Myocytes, Cardiac/metabolism -MH - *Ventricular Remodeling -PMC - PMC2900478 -MID - NIHMS195730 -EDAT- 2010/06/19 06:00 -MHDA- 2010/11/17 06:00 -PMCR- 2011/08/01 -CRDT- 2010/06/19 06:00 -PHST- 2010/01/11 00:00 [received] -PHST- 2010/02/10 00:00 [accepted] -PHST- 2010/06/19 06:00 [entrez] -PHST- 2010/06/19 06:00 [pubmed] -PHST- 2010/11/17 06:00 [medline] -PHST- 2011/08/01 00:00 [pmc-release] -AID - 10.1007/s12265-010-9174-x [doi] -PST - ppublish -SO - J Cardiovasc Transl Res. 2010 Aug;3(4):374-83. doi: 10.1007/s12265-010-9174-x. - Epub 2010 Mar 16. - -PMID- 23470685 -OWN - NLM -STAT- MEDLINE -DCOM- 20130827 -LR - 20220223 -IS - 1530-6550 (Print) -IS - 1530-6550 (Linking) -VI - 13 -IP - 4 -DP - 2012 -TI - Percutaneous closure of prosthetic paravalvular leaks. -PG - e169-75 -LID - 10.3909/ricm0612 [doi] -AB - Paravalvular leaks (PVLs) are relatively common after valve replacement. These - leaks are usually small and disappear during the follow-up. Symptomatic PVLs - occur in 1% to 2% of patients undergoing valve replacement. PVLs causing clinical - consequences require surgical intervention. Surgery is considered the gold - standard of dehiscence repair. In recent years, the use of percutaneous closure - devices for closing PVLs has been proposed as an alternative to surgery. Such - techniques are less invasive and can be used in most high-risk patients instead - of performing repeat surgery. This article describes how to assess the leak as - well as the technical aspects of the procedure. -FAU - Grabowski, Maciej -AU - Grabowski M -AD - Department of Valvular Heart Disease, Institute of Cardiology, Warsaw, Poland. -FAU - Heretyk, Hanna -AU - Heretyk H -FAU - Demkow, Marcin -AU - Demkow M -FAU - Hryniewiecki, Tomasz -AU - Hryniewiecki T -LA - eng -PT - Journal Article -PT - Review -PL - Singapore -TA - Rev Cardiovasc Med -JT - Reviews in cardiovascular medicine -JID - 100960007 -SB - IM -MH - Echocardiography -MH - Echocardiography, Transesophageal -MH - *Heart Valve Prosthesis -MH - Humans -MH - *Percutaneous Coronary Intervention -MH - *Prosthesis Failure -EDAT- 2012/01/01 00:00 -MHDA- 2013/08/28 06:00 -CRDT- 2013/03/09 06:00 -PHST- 2013/03/09 06:00 [entrez] -PHST- 2012/01/01 00:00 [pubmed] -PHST- 2013/08/28 06:00 [medline] -AID - 10.3909/ricm0612 [doi] -PST - ppublish -SO - Rev Cardiovasc Med. 2012;13(4):e169-75. doi: 10.3909/ricm0612. - -PMID- 22340831 -OWN - NLM -STAT- MEDLINE -DCOM- 20120611 -LR - 20250529 -IS - 1876-7591 (Electronic) -IS - 1936-878X (Print) -IS - 1876-7591 (Linking) -VI - 5 -IP - 2 -DP - 2012 Feb -TI - Targeted metabolic imaging to improve the management of heart disease. -PG - 214-26 -LID - 10.1016/j.jcmg.2011.11.009 [doi] -AB - Tracer techniques are powerful methods for assessing rates of biological - processes in vivo. A case in point is intermediary metabolism of energy providing - substrates, a central feature of every living cell. In the heart, the tight - coupling between metabolism and contractile function offers an opportunity for - the simultaneous assessment of cardiac performance at different levels in vivo: - coronary flow, myocardial perfusion, oxygen delivery, metabolism, and - contraction. Noninvasive imaging techniques used to identify the metabolic - footprints of either normal or perturbed cardiac function are discussed. -CI - Copyright © 2012 American College of Cardiology Foundation. Published by - Elsevier Inc. All rights reserved. -FAU - Osterholt, Moritz -AU - Osterholt M -AD - Department of Internal Medicine/Division of Cardiology, University of Texas - Medical School at Houston, Houston, Texas 77030, USA. -FAU - Sen, Shiraj -AU - Sen S -FAU - Dilsizian, Vasken -AU - Dilsizian V -FAU - Taegtmeyer, Heinrich -AU - Taegtmeyer H -LA - eng -GR - R01 HL061483/HL/NHLBI NIH HHS/United States -GR - R01 HL073162/HL/NHLBI NIH HHS/United States -GR - T32 HL007591/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Review -PL - United States -TA - JACC Cardiovasc Imaging -JT - JACC. Cardiovascular imaging -JID - 101467978 -RN - 0 (Amino Acids) -RN - 0 (Fatty Acids) -RN - 0 (Radiopharmaceuticals) -RN - IY9XDZ35W2 (Glucose) -SB - IM -MH - Amino Acids/metabolism -MH - Energy Metabolism -MH - Fatty Acids/metabolism -MH - Glucose/metabolism -MH - Heart Diseases/diagnostic imaging/*metabolism/physiopathology -MH - Humans -MH - *Magnetic Resonance Spectroscopy -MH - Myocardium/*metabolism -MH - *Positron-Emission Tomography -MH - *Radiopharmaceuticals -MH - *Tomography, Emission-Computed, Single-Photon -PMC - PMC3302688 -MID - NIHMS354027 -EDAT- 2012/02/22 06:00 -MHDA- 2012/06/12 06:00 -PMCR- 2013/02/01 -CRDT- 2012/02/21 06:00 -PHST- 2011/08/16 00:00 [received] -PHST- 2011/11/14 00:00 [revised] -PHST- 2011/11/28 00:00 [accepted] -PHST- 2012/02/21 06:00 [entrez] -PHST- 2012/02/22 06:00 [pubmed] -PHST- 2012/06/12 06:00 [medline] -PHST- 2013/02/01 00:00 [pmc-release] -AID - S1936-878X(11)00884-9 [pii] -AID - 10.1016/j.jcmg.2011.11.009 [doi] -PST - ppublish -SO - JACC Cardiovasc Imaging. 2012 Feb;5(2):214-26. doi: 10.1016/j.jcmg.2011.11.009. - -PMID- 17516753 -OWN - NLM -STAT- MEDLINE -DCOM- 20070605 -LR - 20210527 -IS - 1543-2165 (Electronic) -IS - 0003-9985 (Linking) -VI - 131 -IP - 3 -DP - 2007 Mar -TI - The role of periadventitial fat in atherosclerosis. -PG - 481-7 -AB - CONTEXT: It has become increasingly evident that adipose tissue is a - multifunctional organ that produces and secretes multiple paracrine and endocrine - factors. Research into obesity, insulin resistance, and diabetes has identified a - proinflammatory state associated with obesity. Substantial differences between - subcutaneous and omental fat have been noted, including the fact that omental fat - produces relatively more inflammatory cytokines. Periadventitial fat, as a - specific adipose tissue subset, has been overlooked in the field of - atherosclerosis despite its potential diagnostic and therapeutic implications. - OBJECTIVE: To review (1) evidence for the role of adventitial and periadventitial - fat in vessel remodeling after injury, (2) the relationship between adventitial - inflammation and atherosclerosis, (3) the association between periadventitial fat - and plaque inflammation, and (4) the diagnostic and therapeutic implications of - these roles and relationships for the progression of atherosclerosis. DATA - SOURCES: We present new data showing greater uptake of iron, administered in the - form of superparamagnetic iron oxide, in the periadventitial fat of - atherosclerotic mice than in control mice. In addition, macrophage density in the - periadventitial fat of lipid-rich plaques is increased compared with - fibrocalcific plaques. CONCLUSIONS: There is a striking paucity of data on the - relationship between the periadventitial fat of coronary arteries and - atherosclerosis. Greater insight into this relationship might be instrumental in - making strides into the pathophysiology, diagnosis, and treatment of coronary - artery disease. -FAU - Vela, Deborah -AU - Vela D -AD - Texas Heart Institute at St Luke's Episcopal Hospital, Houston, USA. -FAU - Buja, L Maximilian -AU - Buja LM -FAU - Madjid, Mohammad -AU - Madjid M -FAU - Burke, Alan -AU - Burke A -FAU - Naghavi, Morteza -AU - Naghavi M -FAU - Willerson, James T -AU - Willerson JT -FAU - Casscells, S Ward -AU - Casscells SW -FAU - Litovsky, Silvio -AU - Litovsky S -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Arch Pathol Lab Med -JT - Archives of pathology & laboratory medicine -JID - 7607091 -RN - 0 (Ferric Compounds) -RN - 1K09F3G675 (ferric oxide) -RN - E1UOL152H7 (Iron) -SB - IM -CIN - Arch Pathol Lab Med. 2007 Mar;131(3):346-7. doi: 10.5858/2007-131-346-PF. PMID: - 17516736 -CIN - Arch Pathol Lab Med. 2007 Dec;131(12):1766; author reply 1766-7. doi: - 10.5858/2007-131-1766a-PATTAE. PMID: 18081430 -MH - Adipose Tissue/immunology/*metabolism -MH - Animals -MH - Arteries/*metabolism -MH - Atherosclerosis/*etiology/metabolism -MH - Connective Tissue/metabolism/pathology -MH - Coronary Vessels/metabolism -MH - Ferric Compounds/pharmacokinetics -MH - Humans -MH - Inflammation/*complications -MH - Iron/pharmacokinetics -MH - Mice -MH - Risk Factors -RF - 75 -EDAT- 2007/05/23 09:00 -MHDA- 2007/06/06 09:00 -CRDT- 2007/05/23 09:00 -PHST- 2006/08/15 00:00 [accepted] -PHST- 2007/05/23 09:00 [pubmed] -PHST- 2007/06/06 09:00 [medline] -PHST- 2007/05/23 09:00 [entrez] -AID - RA5-090 [pii] -AID - 10.5858/2007-131-481-TROPFI [doi] -PST - ppublish -SO - Arch Pathol Lab Med. 2007 Mar;131(3):481-7. doi: 10.5858/2007-131-481-TROPFI. - -PMID- 21149829 -OWN - NLM -STAT- MEDLINE -DCOM- 20110902 -LR - 20110510 -IS - 1940-4034 (Electronic) -IS - 1074-2484 (Linking) -VI - 16 -IP - 2 -DP - 2011 Jun -TI - Mild hypothermia as a cardioprotective approach for acute myocardial infarction: - laboratory to clinical application. -PG - 131-9 -LID - 10.1177/1074248410387280 [doi] -AB - In many animal models, mild therapeutic hypothermia is a powerful intervention, - reducing myocardial infarct size, reducing the no-reflow phenomenon, and - improving healing after infarction. Cooling in these models has been produced by - various means including whole-body hypothermia, synchronized hypothermic coronary - venous retro-perfusion, heat exchangers, and regional hypothermia targeting the - heart alone. However, in humans, the most widely used techniques are surface - cooling and cooling by endovascular heat-exchange catheters. The reduction in - temperature necessary to produce cardioprotection is mild (32-34°C), appears to - have no detrimental effects on left ventricular function or regional myocardial - blood flow, and may improve microvascular reflow to previously ischemic heart - tissue. It has been shown in experimental and clinical studies that for - therapeutic hypothermia to be effective it must be (1) initiated as early as - possible after the onset of ischemia and (2) initiated before reperfusion. This - may require initiation of hypothermia in the ambulance, well before mechanical - reperfusion occurs. The mechanisms of protection produced by hypothermia have yet - to be conclusively determined but may include a decrease in tissue metabolic - rate, preservation of high energy phosphates, a reduction in tissue apoptosis or - induction of heat shock proteins. -FAU - Hale, Sharon L -AU - Hale SL -AD - The Heart Institute of Good Samaritan Hospital, Los Angeles, CA 90017, USA. - sharon.hale@netscape.com -FAU - Kloner, Robert A -AU - Kloner RA -LA - eng -PT - Journal Article -PT - Review -DEP - 20101213 -PL - United States -TA - J Cardiovasc Pharmacol Ther -JT - Journal of cardiovascular pharmacology and therapeutics -JID - 9602617 -SB - IM -MH - Animals -MH - *Body Temperature -MH - Catheterization -MH - Disease Models, Animal -MH - Humans -MH - Hypothermia, Induced/*methods -MH - Myocardial Infarction/physiopathology/*therapy -MH - Time Factors -EDAT- 2010/12/15 06:00 -MHDA- 2011/09/03 06:00 -CRDT- 2010/12/15 06:00 -PHST- 2010/12/15 06:00 [entrez] -PHST- 2010/12/15 06:00 [pubmed] -PHST- 2011/09/03 06:00 [medline] -AID - 1074248410387280 [pii] -AID - 10.1177/1074248410387280 [doi] -PST - ppublish -SO - J Cardiovasc Pharmacol Ther. 2011 Jun;16(2):131-9. doi: 10.1177/1074248410387280. - Epub 2010 Dec 13. - -PMID- 18805897 -OWN - NLM -STAT- MEDLINE -DCOM- 20081222 -LR - 20250529 -IS - 0363-6135 (Print) -IS - 1522-1539 (Electronic) -IS - 0363-6135 (Linking) -VI - 295 -IP - 5 -DP - 2008 Nov -TI - Human neutrophil peptides: a novel potential mediator of inflammatory - cardiovascular diseases. -PG - H1817-24 -LID - 10.1152/ajpheart.00472.2008 [doi] -AB - The traditional view of atherosclerosis has recently been expanded from a - predominantly lipid retentive disease to a coupling of inflammatory mechanisms - and dyslipidemia. Studies have suggested a novel role for polymorphonuclear - neutrophil (PMN)-dominant inflammation in the development of atherosclerosis. - Human neutrophil peptides (HNPs), also known as alpha-defensins, are secreted and - released from PMN granules upon activation and are conventionally involved in - microbial killing. Current evidence suggests an important immunomodulative role - for these peptides. HNP levels are markedly increased in inflammatory diseases - including sepsis and acute coronary syndromes. They have been found within the - intima of human atherosclerotic arteries, and their deposition in the skin - correlates with the severity of coronary artery diseases. HNPs form complexes - with LDL in solution and increase LDL binding to the endothelial surface. HNPs - have also been shown to contribute to endothelial dysfunction, lipid metabolism - disorder, and the inhibition of fibrinolysis. Given the emerging relationship - between PMN-dominant inflammation and atherosclerosis, HNPs may serve as a link - between them and as a biological marker and potential therapeutic target in - cardiovascular diseases including coronary artery diseases and acute coronary - syndromes. -FAU - Quinn, Kieran -AU - Quinn K -AD - The Keenan Research Centre in the Li Ka Shing Knowledge Institute of Saint - Michael's Hospital, Toronto, ON, Canada. -FAU - Henriques, Melanie -AU - Henriques M -FAU - Parker, Tom -AU - Parker T -FAU - Slutsky, Arthur S -AU - Slutsky AS -FAU - Zhang, Haibo -AU - Zhang H -LA - eng -GR - 69042-1/CAPMC/CIHR/Canada -GR - 77818-1/CAPMC/CIHR/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080919 -PL - United States -TA - Am J Physiol Heart Circ Physiol -JT - American journal of physiology. Heart and circulatory physiology -JID - 100901228 -RN - 0 (Biomarkers) -RN - 0 (Inflammation Mediators) -RN - 0 (alpha-Defensins) -SB - IM -MH - Atherosclerosis/immunology -MH - Biomarkers/metabolism -MH - Cardiovascular Diseases/*immunology -MH - Humans -MH - Inflammation/*immunology -MH - Inflammation Mediators/*metabolism -MH - Neutrophils/*immunology -MH - Signal Transduction -MH - alpha-Defensins/*metabolism -PMC - PMC4896811 -MID - CAMS3639 -OID - NLM: CAMS3639 -EDAT- 2008/09/23 09:00 -MHDA- 2008/12/23 09:00 -PMCR- 2016/06/07 -CRDT- 2008/09/23 09:00 -PHST- 2008/09/23 09:00 [pubmed] -PHST- 2008/12/23 09:00 [medline] -PHST- 2008/09/23 09:00 [entrez] -PHST- 2016/06/07 00:00 [pmc-release] -AID - 00472.2008 [pii] -AID - 10.1152/ajpheart.00472.2008 [doi] -PST - ppublish -SO - Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H1817-24. doi: - 10.1152/ajpheart.00472.2008. Epub 2008 Sep 19. - -PMID- 23563369 -OWN - NLM -STAT- MEDLINE -DCOM- 20131231 -LR - 20220321 -IS - 0971-5916 (Print) -IS - 0975-9174 (Electronic) -IS - 0971-5916 (Linking) -VI - 137 -IP - 2 -DP - 2013 Feb -TI - Chronic obstructive pulmonary disease. -PG - 251-69 -AB - The global prevalence of physiologically defined chronic obstructive pulmonary - disease (COPD) in adults aged >40 yr is approximately 9-10 per cent. Recently, - the Indian Study on Epidemiology of Asthma, Respiratory Symptoms and Chronic - Bronchitis in Adults had shown that the overall prevalence of chronic bronchitis - in adults >35 yr is 3.49 per cent. The development of COPD is multifactorial and - the risk factors of COPD include genetic and environmental factors. Pathological - changes in COPD are observed in central airways, small airways and alveolar - space. The proposed pathogenesis of COPD includes proteinase-antiproteinase - hypothesis, immunological mechanisms, oxidant-antioxidant balance, systemic - inflammation, apoptosis and ineffective repair. Airflow limitation in COPD is - defined as a postbronchodilator FEV1 (forced expiratory volume in 1 sec) to FVC - (forced vital capacity) ratio <0.70. COPD is characterized by an accelerated - decline in FEV1. Co morbidities associated with COPD are cardiovascular disorders - (coronary artery disease and chronic heart failure), hypertension, metabolic - diseases (diabetes mellitus, metabolic syndrome and obesity), bone disease - (osteoporosis and osteopenia), stroke, lung cancer, cachexia, skeletal muscle - weakness, anaemia, depression and cognitive decline. The assessment of COPD is - required to determine the severity of the disease, its impact on the health - status and the risk of future events (e.g., exacerbations, hospital admissions or - death) and this is essential to guide therapy. COPD is treated with inhaled - bronchodilators, inhaled corticosteroids, oral theophylline and oral - phosphodiesterase-4 inhibitor. Non pharmacological treatment of COPD includes - smoking cessation, pulmonary rehabilitation and nutritional support. Lung volume - reduction surgery and lung transplantation are advised in selected severe - patients. Global strategy for the diagnosis, management and prevention of Chronic - Obstructive Pulmonary Disease guidelines recommend influenza and pneumococcal - vaccinations. -FAU - Vijayan, V K -AU - Vijayan VK -AD - Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India. - vijayanvk@hotmail.com -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian J Med Res -JT - The Indian journal of medical research -JID - 0374701 -RN - 0 (Bronchodilator Agents) -SB - IM -MH - *Air Pollution -MH - Asthma/complications/epidemiology -MH - Bronchodilator Agents/*administration & dosage -MH - Comorbidity -MH - Humans -MH - India/epidemiology -MH - Pulmonary Disease, Chronic Obstructive/*drug - therapy/epidemiology/etiology/*physiopathology -MH - Risk Factors -PMC - PMC3657849 -EDAT- 2013/04/09 06:00 -MHDA- 2014/01/01 06:00 -PMCR- 2013/02/01 -CRDT- 2013/04/09 06:00 -PHST- 2013/04/09 06:00 [entrez] -PHST- 2013/04/09 06:00 [pubmed] -PHST- 2014/01/01 06:00 [medline] -PHST- 2013/02/01 00:00 [pmc-release] -AID - IndianJMedRes_2013_137_2_251_109578 [pii] -AID - IJMR-137-251 [pii] -PST - ppublish -SO - Indian J Med Res. 2013 Feb;137(2):251-69. - -PMID- 24188222 -OWN - NLM -STAT- MEDLINE -DCOM- 20140527 -LR - 20140808 -IS - 1558-2264 (Electronic) -IS - 0733-8651 (Linking) -VI - 31 -IP - 4 -DP - 2013 Nov -TI - Durable mechanical circulatory support in advanced heart failure: a critical care - cardiology perspective. -PG - 581-93, viii-ix -LID - S0733-8651(13)00066-0 [pii] -LID - 10.1016/j.ccl.2013.07.003 [doi] -AB - Though cardiac transplantation for advanced heart disease patients remains - definitive therapy for patients with advanced heart failure, it is challenged by - inadequate donor supply, causing durable mechanical circulatory support (MCS) to - slowly become a new primary standard. Selecting appropriate patients for MCS - involves meeting a number of prespecifications as is required in evaluation for - cardiac transplant candidacy. As technology evolves to bring forth more durable - smaller devices, selection criteria for appropriate MCS recipients will likely - expand to encompass a broader, less sick population. The "Holy Grail" for MCS - will be a focus on clinical recovery and explantation of devices rather than the - currently more narrowly defined indications of bridge to transplantation or - lifetime device therapy. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Lala, Anuradha -AU - Lala A -AD - Department of Medicine, Division of Cardiology, Brigham and Women's Hospital, - Harvard Medical School, 75 Francis Street, A3, Boston, MA 02115, USA. -FAU - Mehra, Mandeep R -AU - Mehra MR -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -SB - IM -EIN - Cardiol Clin. 2014 May;32(2):xiii -MH - Arrhythmias, Cardiac/prevention & control -MH - Clinical Trials as Topic -MH - Coronary Care Units -MH - Critical Care -MH - Forecasting -MH - Heart Failure/*therapy -MH - *Heart-Assist Devices -MH - Hemorrhage/prevention & control -MH - Humans -MH - Hypertension/prevention & control -MH - Hypotension/prevention & control -MH - Patient Selection -MH - Prosthesis Design -MH - Prosthesis Failure -MH - Prosthesis-Related Infections/prevention & control -MH - Thrombosis/prevention & control -OTO - NOTNLM -OT - Device therapy -OT - Heart failure -OT - Mechanical circulatory support -OT - Recovery -OT - Transplantation -EDAT- 2013/11/06 06:00 -MHDA- 2014/05/28 06:00 -CRDT- 2013/11/06 06:00 -PHST- 2013/11/06 06:00 [entrez] -PHST- 2013/11/06 06:00 [pubmed] -PHST- 2014/05/28 06:00 [medline] -AID - S0733-8651(13)00066-0 [pii] -AID - 10.1016/j.ccl.2013.07.003 [doi] -PST - ppublish -SO - Cardiol Clin. 2013 Nov;31(4):581-93, viii-ix. doi: 10.1016/j.ccl.2013.07.003. - -PMID- 21786252 -OWN - NLM -STAT- MEDLINE -DCOM- 20111201 -LR - 20171206 -IS - 1724-6040 (Electronic) -IS - 0391-3988 (Linking) -VI - 34 -IP - 7 -DP - 2011 Jul -TI - Surgical therapy of end-stage heart failure: understanding cell-mediated - mechanisms interacting with myocardial damage. -PG - 529-45 -LID - 10.5301/ijao.5000004 [doi] -AB - Worldwide, cardiovascular disease results in an estimated 14.3 million deaths per - year, giving rise to an increased demand for alternative and advanced treatment. - Current approaches include medical management, cardiac transplantation, device - therapy, and, most recently, stem cell therapy. Research into cell-based - therapies has shown this option to be a promising alternative to the conventional - methods. In contrast to early trials, modern approaches now attempt to isolate - specific stem cells, as well as increase their numbers by means of amplifying in - a culture environment. The method of delivery has also been improved to minimize - the risk of micro-infarcts and embolization, which were often observed after the - use of coronary catheterization. The latest approach entails direct, surgical, - trans-epicardial injection of the stem cell mixture, as well as the use of - tissue-engineered meshes consisting of embedded progenitor cells. -FAU - Ghodsizad, Ali -AU - Ghodsizad A -AD - The Methodist Hospital, Methodist DeBakey Heart Center, TMH, Texas, Medical - Center, Houston, Texas, USA. aghodsi@gmx.org -FAU - Loebe, Mathias -AU - Loebe M -FAU - Piechaczek, Christoph -AU - Piechaczek C -FAU - Bordel, Viktor -AU - Bordel V -FAU - Ungerer, Matthias N -AU - Ungerer MN -FAU - Gregoric, Igor -AU - Gregoric I -FAU - Bruckner, Brian -AU - Bruckner B -FAU - Noon, George P -AU - Noon GP -FAU - Karck, Matthias -AU - Karck M -FAU - Ruhparwar, Arjang -AU - Ruhparwar A -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Int J Artif Organs -JT - The International journal of artificial organs -JID - 7802649 -SB - IM -MH - Animals -MH - *Cardiac Surgical Procedures -MH - Cell Differentiation -MH - Cell Proliferation -MH - Heart Failure/pathology/physiopathology/*surgery -MH - Humans -MH - Myocardium/*pathology -MH - Myocytes, Cardiac/pathology/*transplantation -MH - Regeneration -MH - *Stem Cell Transplantation -MH - *Tissue Engineering -MH - Tissue Scaffolds -MH - Treatment Outcome -EDAT- 2011/07/26 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2011/07/26 06:00 -PHST- 2011/05/11 00:00 [accepted] -PHST- 2011/07/26 06:00 [entrez] -PHST- 2011/07/26 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -AID - FA14E24D-3968-4562-A841-55A9171F8B2C [pii] -AID - 10.5301/ijao.5000004 [doi] -PST - ppublish -SO - Int J Artif Organs. 2011 Jul;34(7):529-45. doi: 10.5301/ijao.5000004. - -PMID- 20014213 -OWN - NLM -STAT- MEDLINE -DCOM- 20100406 -LR - 20240718 -IS - 1932-8737 (Electronic) -IS - 0160-9289 (Print) -IS - 0160-9289 (Linking) -VI - 32 -IP - 12 -DP - 2009 Dec -TI - Myocardial stunning following combined modality combretastatin-based - chemotherapy: two case reports and review of the literature. -PG - E80-4 -LID - 10.1002/clc.20685 [doi] -AB - Myocardial stunning, known as stress cardiomyopathy, broken-heart syndrome, - transient left ventricular apical ballooning, and Takotsubo cardiomyopathy, has - been reported after many extracardiac stressors, but not following chemotherapy. - We report 2 cases with characteristic electrocardiographic and echocardiographic - features following combined modality therapy with combretastatin, a - vascular-disrupting agent being studied for treatment of anaplastic thyroid - cancer. In 1 patient, an ECG performed per protocol 18 hours after drug - initiation showed deep, symmetric T-wave inversions in limb leads I and aVL and - precordial leads V(2) through V(6). Echocardiography showed mildly reduced - overall left ventricular systolic function with akinesis of the entire apex. The - patient had mild elevations of troponin I. Coronary angiography revealed no - epicardial coronary artery disease. The electrocardiographic and - echocardiographic abnormalities resolved after several weeks. The patient remains - stable from a cardiovascular standpoint and has not had a recurrence during - follow-up. An electrocardiogram performed per protocol in a second patient showed - deep, symmetric T-wave inversions throughout the precordial leads and a prolonged - QT interval. Echocardiography showed mildly reduced left ventricular function - with hypokinesis of the apical-septal wall. Acute coronary syndrome was ruled - out, and both the electrocardiographic and echocardiographic changes resolved at - follow-up. Although the patient remained pain-free without recurrence of anginal - symptoms during long-term follow-up, the patient developed progressive malignancy - and died. -FAU - Bhakta, Shyam -AU - Bhakta S -AD - Harrington-McLaughlin Heart and Vascular Institute, Ireland Cancer Center, and - Department of Radiology, University Hospitals-Case Medical Center, Cleveland, - Ohio 44106, USA. -FAU - Flick, Susan M -AU - Flick SM -FAU - Cooney, Matthey M -AU - Cooney MM -FAU - Greskovich, John F -AU - Greskovich JF -FAU - Gilkeson, Robert C -AU - Gilkeson RC -FAU - Remick, Scot C -AU - Remick SC -FAU - Ortiz, Jose -AU - Ortiz J -LA - eng -PT - Case Reports -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Clin Cardiol -JT - Clinical cardiology -JID - 7903272 -RN - 0 (Bibenzyls) -RN - 0 (Troponin I) -RN - 7O62J06F18 (combretastatin) -SB - IM -MH - Aged -MH - Antineoplastic Combined Chemotherapy Protocols/*adverse effects -MH - Bibenzyls/administration & dosage/*adverse effects -MH - Carcinoma/drug therapy -MH - Diagnostic Imaging -MH - Electrocardiography -MH - Female -MH - Humans -MH - Myocardial Stunning/*chemically induced/*diagnosis -MH - Thyroid Neoplasms/drug therapy -MH - Troponin I/blood -PMC - PMC6653067 -EDAT- 2009/12/17 06:00 -MHDA- 2010/04/07 06:00 -PMCR- 2009/12/14 -CRDT- 2009/12/17 06:00 -PHST- 2009/12/17 06:00 [entrez] -PHST- 2009/12/17 06:00 [pubmed] -PHST- 2010/04/07 06:00 [medline] -PHST- 2009/12/14 00:00 [pmc-release] -AID - CLC20685 [pii] -AID - 10.1002/clc.20685 [doi] -PST - ppublish -SO - Clin Cardiol. 2009 Dec;32(12):E80-4. doi: 10.1002/clc.20685. - -PMID- 23562120 -OWN - NLM -STAT- MEDLINE -DCOM- 20131205 -LR - 20130408 -IS - 1551-7136 (Print) -IS - 1551-7136 (Linking) -VI - 9 -IP - 2 -DP - 2013 Apr -TI - Mechanisms of stress (takotsubo) cardiomyopathy. -PG - 197-205, ix -LID - S1551-7136(12)00125-0 [pii] -LID - 10.1016/j.hfc.2012.12.012 [doi] -AB - Stress cardiomyopathy is a form of reversible systolic dysfunction of the mid and - apical left ventricle with pathologic changes of the electrocardiogram in the - absence of an obstructive coronary artery disease. The prevalence of stress - cardiomyopathy among patients with symptoms suggestive of myocardial infarction - is 0.7% to 2.5%, and it is found predominantly in postmenopausal women (90%). No - large studies have confirmed the cause of stress cardiomyopathy. Published data - suggest that substantially elevated plasma catecholamine levels, due to emotional - or physical stress, may be relevant. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Szardien, Sebastian -AU - Szardien S -AD - Department of Cardiology, Kerckhoff Heart and Thorax Center, Benekestrasse 2-8, - Bad Nauheim 61231, Germany. s.szardien@kerckhoff-fgi.de -FAU - Möllmann, Helge -AU - Möllmann H -FAU - Willmer, Matthias -AU - Willmer M -FAU - Akashi, Yoshihiro J -AU - Akashi YJ -FAU - Hamm, Christian W -AU - Hamm CW -FAU - Nef, Holger M -AU - Nef HM -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Clin -JT - Heart failure clinics -JID - 101231934 -RN - 0 (Catecholamines) -SB - IM -MH - Catecholamines/metabolism -MH - Female -MH - Humans -MH - Takotsubo Cardiomyopathy/etiology/genetics/*physiopathology -MH - Ventricular Dysfunction, Left -EDAT- 2013/04/09 06:00 -MHDA- 2013/12/16 06:00 -CRDT- 2013/04/09 06:00 -PHST- 2013/04/09 06:00 [entrez] -PHST- 2013/04/09 06:00 [pubmed] -PHST- 2013/12/16 06:00 [medline] -AID - S1551-7136(12)00125-0 [pii] -AID - 10.1016/j.hfc.2012.12.012 [doi] -PST - ppublish -SO - Heart Fail Clin. 2013 Apr;9(2):197-205, ix. doi: 10.1016/j.hfc.2012.12.012. - -PMID- 19753517 -OWN - NLM -STAT- MEDLINE -DCOM- 20091123 -LR - 20101118 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 16 -IP - 5 -DP - 2009 -TI - Impaired renal function in acute myocardial infarction. -PG - 400-6 -AB - Impaired renal function is a risk factor for cardiovascular disease and an - adverse prognostic factor in patients with established cardiovascular disease. In - addition, with current widespread use of invasive procedures in the treatment of - acute myocardial infarction, contrast-induced nephropathy is a growing problem in - this patient population. In acute myocardial infarction, impaired renal function - may result from underlying kidney disease, acute renal failure, and the effect of - drugs and contrast agents used during diagnostic procedures or treatment. These - various causes may coexist, resulting in significantly worse outcomes. Prompt - recognition of the degree of renal function impairment and institution of - appropriate preventive and therapeutic measures are among major goals of - in-hospital management of these patients. A commonly used method to evaluate - renal function is the determination of glomerular filtration rate. Appropriate - nephroprotective treatment should be used in patients at risk of contrast-induced - nephropathy. The most commonly used methods include the use of iso-osmotic - contrast agents and appropriate hydration in the periprocedural period. Studies - are currently under way to evaluate nephroprotective properties of other drugs - such as N-acetylcysteine, sodium chloride and sodium bicarbonate solutions, - mannitol, and statins. Results of some studies suggest that these measures may - effectively reduce the number of renal function deterioration events in patients - with acute myocardial infarction. Regardless of the cause, impaired renal - function in acute myocardial infarction is a significant adverse prognostic - factor. Thus, despite some inconsistent views regarding the optimal management - strategy, intensive diagnostic, preventive, and therapeutic measures are clearly - necessary in patients with acute myocardial infarction and impaired renal - function. -FAU - Lekston, Andrzej -AU - Lekston A -AD - 3rd Chair and Department of Cardiology, Medical University of Silesia, Silesian - Centre for Heart Diseases, Zabrze, Poland. -FAU - Kurek, Anna -AU - Kurek A -FAU - Tynior, Barbara -AU - Tynior B -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -RN - 0 (Cardiovascular Agents) -RN - 0 (Contrast Media) -SB - IM -MH - Acute Disease -MH - Angioplasty, Balloon, Coronary/adverse effects -MH - Cardiovascular Agents/adverse effects -MH - Chronic Disease -MH - Contrast Media/adverse effects -MH - Disease Progression -MH - *Glomerular Filtration Rate/drug effects -MH - Humans -MH - Kidney/drug effects/*physiopathology -MH - Kidney Diseases/complications/*etiology/physiopathology/therapy -MH - Myocardial Infarction/*complications/diagnosis/physiopathology/therapy -MH - Practice Guidelines as Topic -MH - Renal Insufficiency/etiology/physiopathology -MH - Risk Assessment -MH - Risk Factors -MH - Severity of Illness Index -MH - Terminology as Topic -MH - Treatment Outcome -RF - 40 -EDAT- 2009/09/16 06:00 -MHDA- 2009/12/16 06:00 -CRDT- 2009/09/16 06:00 -PHST- 2009/09/16 06:00 [entrez] -PHST- 2009/09/16 06:00 [pubmed] -PHST- 2009/12/16 06:00 [medline] -PST - ppublish -SO - Cardiol J. 2009;16(5):400-6. - -PMID- 18760619 -OWN - NLM -STAT- MEDLINE -DCOM- 20090305 -LR - 20250623 -IS - 1873-734X (Electronic) -IS - 1010-7940 (Linking) -VI - 34 -IP - 6 -DP - 2008 Dec -TI - Early and late outcome of left ventricular reconstruction surgery in ischemic - heart disease. -PG - 1149-57 -LID - 10.1016/j.ejcts.2008.06.045 [doi] -AB - A systematic review of the literature was performed to determine early and late - mortality associated with left ventricular (LV) reconstruction surgery and to - assess the influence of different surgical techniques, concomitant surgical - procedures, clinical and hemodynamic parameters on mortality. The MEDLINE - database (January 1980-January 2005) was searched and from the pooled data, - hospital mortality and survival were calculated. Summary estimates of relative - risks (RR) were calculated for the techniques that were used and for concomitant - coronary artery bypass grafting (CABG) and mitral valve surgery. The - risk-adjusted relationships between mortality and clinical and hemodynamic - parameters were assessed by meta-regression. A total of 62 studies (12,331 - patients) were identified. Weighted average early mortality was 6.9%. Cumulative - 1-year, 5-year and 10-year survival were 88.5%, 71.5% and 53.9%, respectively. - Endoventricular reconstruction (EVR) showed a reduced risk for both early - (RR=0.79, p<0.005) and late (RR=0.67, p<0.001) mortality compared to the linear - repair (early: RR=1.38, p<0.001; late: RR=1.83, p<0.001). Early and late - mortality were mainly cardiac in origin, with as predominant cause heart failure - in respectively 49.7% and 34.5% of the cases. Ventricular arrhythmias caused - 16.6% of early deaths and 17.2% of late deaths. Concomitant CABG significantly - decreased late mortality (RR=0.28, p<0.001) without increasing early mortality - (RR=1.018, p=0.858). Concomitant mitral valve surgery showed both an increased - risk for early (RR=1.57, p=0.001) and late mortality (RR=4.28, p<0.001). No - clinical or hemodynamic parameters were found to influence mortality. It is - noteworthy that only one third of patients included in the current analysis were - operated for heart failure (14 studies, 4135 patients). In this group we noted an - early mortality of 11.0% with a late mortality (3-year) of 15.2%. This analysis - of pooled literature data showed that LV reconstruction surgery is performed with - acceptable mortality and EVR may be the preferred technique with a reduced risk - for early and late mortality. Concomitant CABG improved outcome, whereas the need - for mitral valve surgery appeared an index of gravity. No clinical or hemodynamic - parameters were found to influence mortality; specifically LV ejection fraction - and LV volumes both did not predict outcome. -FAU - Klein, Patrick -AU - Klein P -AD - Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, - The Netherlands. -FAU - Bax, Jeroen J -AU - Bax JJ -FAU - Shaw, Leslee J -AU - Shaw LJ -FAU - Feringa, Harm H H -AU - Feringa HH -FAU - Versteegh, Michel I M -AU - Versteegh MI -FAU - Dion, Robert A E -AU - Dion RA -FAU - Klautz, Robert J M -AU - Klautz RJ -LA - eng -PT - Journal Article -PT - Systematic Review -DEP - 20080828 -PL - Germany -TA - Eur J Cardiothorac Surg -JT - European journal of cardio-thoracic surgery : official journal of the European - Association for Cardio-thoracic Surgery -JID - 8804069 -SB - IM -CIN - Eur J Cardiothorac Surg. 2009 Jun;35(6):1111; author reply 1111-2. doi: - 10.1016/j.ejcts.2009.02.044. PMID: 19362009 -MH - Coronary Artery Bypass/mortality -MH - Follow-Up Studies -MH - Heart Valve Prosthesis Implantation/mortality -MH - Heart Ventricles/surgery -MH - Hospital Mortality -MH - Humans -MH - Mitral Valve -MH - Myocardial Ischemia/*mortality/*surgery -MH - Postoperative Complications/mortality -MH - Risk -MH - Survival Rate -MH - Time Factors -RF - 99 -EDAT- 2008/09/02 09:00 -MHDA- 2009/03/06 09:00 -CRDT- 2008/09/02 09:00 -PHST- 2008/03/04 00:00 [received] -PHST- 2008/06/26 00:00 [revised] -PHST- 2008/06/27 00:00 [accepted] -PHST- 2008/09/02 09:00 [pubmed] -PHST- 2009/03/06 09:00 [medline] -PHST- 2008/09/02 09:00 [entrez] -AID - S1010-7940(08)00712-4 [pii] -AID - 10.1016/j.ejcts.2008.06.045 [doi] -PST - ppublish -SO - Eur J Cardiothorac Surg. 2008 Dec;34(6):1149-57. doi: - 10.1016/j.ejcts.2008.06.045. Epub 2008 Aug 28. - -PMID- 22365158 -OWN - NLM -STAT- MEDLINE -DCOM- 20120614 -LR - 20220321 -IS - 1558-4488 (Electronic) -IS - 0270-9295 (Linking) -VI - 32 -IP - 1 -DP - 2012 Jan -TI - Cardio-renal syndrome type 1: epidemiology, pathophysiology, and treatment. -PG - 18-25 -LID - 10.1016/j.semnephrol.2011.11.003 [doi] -AB - One third of heart failure admissions may be complicated by acute kidney injury, - resulting in a three-fold increase in length of stay and a greater likelihood of - rehospitalization. Cardio-Renal syndrome type 1 refers to acute decompensation of - cardiac function leading to acute renal failure. It often complicates acute - coronary syndrome and acute decompensated heart failure. Both components of the - syndrome contribute to morbidity and mortality. The pathophysiology of renal - dysfunction is complex. Reduced cardiac output, passive congestion of the - kidneys, and increased intra-abdominal pressure may contribute to the disorder. - The heart, kidneys, renin-angiotensin system, sympathetic nervous system, immune - system, and vasculature interact through intricate feedback loops. An imbalance - in this complex system often will cause deterioration in both cardiac and renal - function. Appreciation of these interactions is crucial to understanding the - overall burden of disease, as well as its natural history, risk factors, - associated morbidity and mortality, and therapeutic implications. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Ismail, Yousif -AU - Ismail Y -AD - Department of Medicine, Cardiology Section, Providence Hospital and Medical - Center, Southfield, MI, USA. -FAU - Kasmikha, Zaid -AU - Kasmikha Z -FAU - Green, Henry L -AU - Green HL -FAU - McCullough, Peter A -AU - McCullough PA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Semin Nephrol -JT - Seminars in nephrology -JID - 8110298 -RN - 0 (Cardiovascular Agents) -RN - 0 (Diuretics) -SB - IM -MH - Acute Disease -MH - Acute Kidney Injury/drug therapy/epidemiology/*etiology/physiopathology -MH - *Cardio-Renal Syndrome/drug therapy/epidemiology/physiopathology -MH - Cardiovascular Agents/*therapeutic use -MH - Diuretics/*therapeutic use -MH - Heart Failure/*complications/drug therapy/epidemiology/physiopathology -MH - Humans -MH - Renin-Angiotensin System/*physiology -EDAT- 2012/03/01 06:00 -MHDA- 2012/06/15 06:00 -CRDT- 2012/02/28 06:00 -PHST- 2012/02/28 06:00 [entrez] -PHST- 2012/03/01 06:00 [pubmed] -PHST- 2012/06/15 06:00 [medline] -AID - S0270-9295(11)00182-3 [pii] -AID - 10.1016/j.semnephrol.2011.11.003 [doi] -PST - ppublish -SO - Semin Nephrol. 2012 Jan;32(1):18-25. doi: 10.1016/j.semnephrol.2011.11.003. - -PMID- 21352576 -OWN - NLM -STAT- MEDLINE -DCOM- 20110805 -LR - 20220321 -IS - 1476-7120 (Electronic) -IS - 1476-7120 (Linking) -VI - 9 -DP - 2011 Feb 27 -TI - Lung ultrasound: a new tool for the cardiologist. -PG - 6 -LID - 10.1186/1476-7120-9-6 [doi] -AB - For many years the lung has been considered off-limits for ultrasound. However, - it has been recently shown that lung ultrasound (LUS) may represent a useful tool - for the evaluation of many pulmonary conditions in cardiovascular disease. The - main application of LUS for the cardiologist is the assessment of B-lines. - B-lines are reverberation artifacts, originating from water-thickened pulmonary - interlobular septa. Multiple B-lines are present in pulmonary congestion, and may - help in the detection, semiquantification and monitoring of extravascular lung - water, in the differential diagnosis of dyspnea, and in the prognostic - stratification of chronic heart failure and acute coronary syndromes. -FAU - Gargani, Luna -AU - Gargani L -AD - Institute of Clinical Physiology, National Research Council of Pisa, Italy. - gargani@ifc.cnr.it -LA - eng -PT - Journal Article -PT - Review -DEP - 20110227 -PL - England -TA - Cardiovasc Ultrasound -JT - Cardiovascular ultrasound -JID - 101159952 -SB - IM -MH - Cardiovascular Diseases/*complications/*diagnostic imaging -MH - Humans -MH - Lung/*diagnostic imaging -MH - Lung Diseases/*complications/*diagnostic imaging -MH - Ultrasonography/*trends -PMC - PMC3059291 -EDAT- 2011/03/01 06:00 -MHDA- 2011/08/06 06:00 -PMCR- 2011/02/27 -CRDT- 2011/03/01 06:00 -PHST- 2010/12/27 00:00 [received] -PHST- 2011/02/27 00:00 [accepted] -PHST- 2011/03/01 06:00 [entrez] -PHST- 2011/03/01 06:00 [pubmed] -PHST- 2011/08/06 06:00 [medline] -PHST- 2011/02/27 00:00 [pmc-release] -AID - 1476-7120-9-6 [pii] -AID - 10.1186/1476-7120-9-6 [doi] -PST - epublish -SO - Cardiovasc Ultrasound. 2011 Feb 27;9:6. doi: 10.1186/1476-7120-9-6. - -PMID- 19643307 -OWN - NLM -STAT- MEDLINE -DCOM- 20090915 -LR - 20220316 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 54 -IP - 6 -DP - 2009 Aug 4 -TI - Heart failure in women: a need for prospective data. -PG - 491-8 -LID - 10.1016/j.jacc.2009.02.066 [doi] -AB - Heart failure affects 5 million Americans, and nearly 50% of these are women. Sex - differences have been noted regarding the underlying etiology, pathophysiology, - and prognosis. Women are less likely to have coronary artery disease and more - likely than men to have hypertension and valvular disease as the underlying - etiology. They often present at an older age with better systolic function than - men. For both sexes, there is significant morbidity, but age-adjusted data reveal - that women have a better survival. Despite these known sex differences, medical - management recommendations are the same for women and men, because prospective - sex-specific clinical trials have not been performed. However, our review raises - some concerns that women might respond differently to therapy. -FAU - Hsich, Eileen M -AU - Hsich EM -AD - Department of Cardiovascular Medicine at the Cleveland Clinic, Cleveland, OH - 44195, USA. Hsiche@ccf.org -FAU - Piña, Ileana L -AU - Piña IL -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Mineralocorticoid Receptor Antagonists) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 26NAK24LS8 (Hydralazine) -RN - 73K4184T59 (Digoxin) -RN - IA7306519N (Isosorbide Dinitrate) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Cardiac Pacing, Artificial -MH - Digoxin/therapeutic use -MH - Female -MH - Heart Failure/epidemiology/*etiology/physiopathology/*therapy -MH - Heart-Assist Devices -MH - Humans -MH - Hydralazine/therapeutic use -MH - Isosorbide Dinitrate/therapeutic use -MH - Male -MH - Mineralocorticoid Receptor Antagonists/therapeutic use -MH - Pacemaker, Artificial -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Risk Factors -MH - Sex Factors -MH - *Women's Health -RF - 62 -EDAT- 2009/08/01 09:00 -MHDA- 2009/09/16 06:00 -CRDT- 2009/08/01 09:00 -PHST- 2008/09/10 00:00 [received] -PHST- 2009/02/05 00:00 [revised] -PHST- 2009/02/09 00:00 [accepted] -PHST- 2009/08/01 09:00 [entrez] -PHST- 2009/08/01 09:00 [pubmed] -PHST- 2009/09/16 06:00 [medline] -AID - S0735-1097(09)01206-6 [pii] -AID - 10.1016/j.jacc.2009.02.066 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2009 Aug 4;54(6):491-8. doi: 10.1016/j.jacc.2009.02.066. - -PMID- 17668082 -OWN - NLM -STAT- MEDLINE -DCOM- 20080110 -LR - 20190608 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Print) -IS - 0828-282X (Linking) -VI - 23 Suppl A -IP - Suppl A -DP - 2007 Aug -TI - Identifying genes for coronary artery disease: An idea whose time has come. -PG - 7A-15A -AB - BACKGROUND: Coronary artery disease (CAD) remains the number one killer in the - western world. Genetics accounts for greater than 50% of the risk for CAD. - Genetic screening and early prevention in individuals identified as being at - increased risk could dramatically reduce the prevalence of CAD, thus - necessitating the identification of genes predisposing to CAD. Studies of genes - identified by the candidate gene approach have not been replicated due, in part, - to inadequate sample size. Genome-wide scan association studies have been limited - by the use of thousands of markers rather than the hundreds of thousands - required, and by the use of hundreds of individuals rather than the thousands - required. Replication of positive findings in an independent population is - essential. To detect a minor allele frequency of 5% or greater with an odds ratio - for risk of 1.3 or greater and 90% power, an estimated 14,000 (9000 affected and - 5000 control) subjects are required. METHODS: The Affymetrix GeneChip Human - Mapping 500K Array Set (Affymetrix Inc, USA) provides a marker every 6000 base - pairs as required, and is being used to genotype 1000 cases of premature CAD and - 1000 normal subjects, followed by replication in 8000 affected individuals and - 4000 control subjects. The phenotype is confirmed or excluded by coronary - arteriograms by catheterization or multislice computed tomography. RESULTS: Since - 2005, more than 800 million genotypes have been performed and analyses performed - on 500 control subjects and 500 affected individuals. Several thousand - significant single nucleotide polymorphisms and 130 clusters associated with CAD - have been identified. CONCLUSIONS: This is the first genome-wide scan using the - 500,000 marker set in a case-control association study for CAD genes. Several - genes associated with CAD appear promising. -FAU - Roberts, Robert -AU - Roberts R -AD - University of Ottawa Heart Institute, Ontario. rroberts@ottawaheart.ca -FAU - Stewart, Alexandre F R -AU - Stewart AF -FAU - Wells, George A -AU - Wells GA -FAU - Williams, Kathryn A -AU - Williams KA -FAU - Kavaslar, Nihan -AU - Kavaslar N -FAU - McPherson, Ruth -AU - McPherson R -LA - eng -GR - T32 HL007706/HL/NHLBI NIH HHS/United States -GR - HL07706-09/HL/NHLBI NIH HHS/United States -GR - RFA-HL-98-007/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Cardiovascular Diseases/epidemiology/*genetics -MH - Case-Control Studies -MH - Female -MH - Gene Frequency/*genetics -MH - Genetic Predisposition to Disease/*epidemiology -MH - Genetic Testing -MH - Genomics/*methods -MH - Genotype -MH - Humans -MH - Male -MH - Odds Ratio -MH - Probability -MH - Reference Values -MH - Sensitivity and Specificity -PMC - PMC2787000 -EDAT- 2007/12/06 09:00 -MHDA- 2008/01/11 09:00 -PMCR- 2008/08/01 -CRDT- 2007/12/06 09:00 -PHST- 2007/12/06 09:00 [pubmed] -PHST- 2008/01/11 09:00 [medline] -PHST- 2007/12/06 09:00 [entrez] -PHST- 2008/08/01 00:00 [pmc-release] -AID - S0828-282X(07)71000-0 [pii] -AID - cjc23007a [pii] -AID - 10.1016/s0828-282x(07)71000-0 [doi] -PST - ppublish -SO - Can J Cardiol. 2007 Aug;23 Suppl A(Suppl A):7A-15A. doi: - 10.1016/s0828-282x(07)71000-0. - -PMID- 22834795 -OWN - NLM -STAT- MEDLINE -DCOM- 20130228 -LR - 20190823 -IS - 1875-533X (Electronic) -IS - 0929-8673 (Linking) -VI - 19 -IP - 24 -DP - 2012 -TI - Chromogranin-A: a multifaceted cardiovascular role in health and disease. -PG - 4042-50 -AB - Chromogranin A (CgA), a major component of the chromaffin granules, is co-stored - and co-released with catecholamines. It is also expressed in extra-adrenal sites, - including the heart. In the rat, CgA localizes in atrial myoendocrine cells, - associated with Atrial Natriuretic Peptide (ANP), and in the conduction system. - In the human heart it is present in the ventricular myocardium, co-localized with - B-type NP (BNP). CgA is the precursor of several biologically active peptides - generated by proteolytic processing also in the heart. Two of them, vasostatin-1 - (VS-1) and catestatin (Cst), inhibit cardiac contraction and relaxation, - counter-regulate beta-adrenergic and endothelinergic stimulation, and protect the - heart against ischemia/reperfusion damages. Recently, clinical studies have - suggested CgA to be involved also in cardiovascular pathologies. High plasma CgA - levels were found in hypertension, chronic and acute heart failure, myocardial - infarction, decompensated and hypertrophic heart, and acute coronary syndromes. - These alterations correlate with those of conventional cardiovascular biomarkers, - such as NP and endothelin-1 (ET-1), and have prognostic relevance, being - indicative of both severity of the disease and mortality. Accordingly, the - current knowledge indicates CgA as a multifaceted peptide in cardiovascular - homeostasis. Whether the influence elicited by the protein on both normal and - failing heart is beneficial and/or detrimental, as well as its implication in the - cardiac neuroendocrine scenario is under intense investigation. This review will - focus on: i) the involvement of CgA and its derived peptides in the mechanisms - which sustain cardiac function and compensation, ii) CgA clinical relevance, and - iii) its putative value as a clinical biomarker. -FAU - Angelone, T -AU - Angelone T -AD - Dept of Cell Biology, University of Calabria, 87036 Arcavacata di Rende (CS), - Italy. t.angelone@unical.it -FAU - Mazza, R -AU - Mazza R -FAU - Cerra, M C -AU - Cerra MC -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Biomarkers) -RN - 0 (Chromogranin A) -RN - 0 (Natriuretic Peptides) -RN - 0 (Serpins) -SB - IM -MH - Animals -MH - Biomarkers/metabolism -MH - Chromaffin Granules/metabolism -MH - Chromogranin A/blood/*metabolism -MH - Heart Diseases/metabolism/pathology -MH - Humans -MH - Hypertension/metabolism/pathology -MH - Myocardium/metabolism -MH - Natriuretic Peptides/metabolism -MH - Serpins/metabolism -EDAT- 2012/07/28 06:00 -MHDA- 2013/03/01 06:00 -CRDT- 2012/07/28 06:00 -PHST- 2012/01/05 00:00 [received] -PHST- 2012/04/30 00:00 [revised] -PHST- 2012/05/01 00:00 [accepted] -PHST- 2012/07/28 06:00 [entrez] -PHST- 2012/07/28 06:00 [pubmed] -PHST- 2013/03/01 06:00 [medline] -AID - CMC-EPUB-20120726-3 [pii] -AID - 10.2174/092986712802430009 [doi] -PST - ppublish -SO - Curr Med Chem. 2012;19(24):4042-50. doi: 10.2174/092986712802430009. - -PMID- 22419421 -OWN - NLM -STAT- MEDLINE -DCOM- 20120710 -LR - 20250626 -IS - 1793-6853 (Electronic) -IS - 0192-415X (Linking) -VI - 40 -IP - 2 -DP - 2012 -TI - A systematic review of the effectiveness of qigong exercise in cardiac - rehabilitation. -PG - 255-67 -AB - The objective of this study was to assess evidence for the efficacy and - effectiveness of Chinese qigong exercise in rehabilitative programs among cardiac - patients. Thirteen databases were searched through to November 2010, and all - controlled clinical trials on Chinese qigong exercise among patients with chronic - heart diseases were included. For each included study, data was extracted and - validity was assessed. Study quality was evaluated and summarized using both the - Jadad Scale and the criteria for levels of evidence. Seven randomized controlled - trials (RCTs) and one non-randomized controlled clinical trial (CCT) published - between 1988 and 2007 met the inclusion criteria. In total, these studies covered - 540 patients with various chronic heart diseases including atrial fibrillation, - coronary artery disease, myocardial infarct, valve replacement, and ischemic - heart disease. Outcome measures emerged in these studies included subjective - outcomes such as symptoms and quality of life; and objective outcomes such as - blood pressure, ECG findings, and exercise capacity, physical activity, balance, - co-ordination, heart rate, and oxygen uptake. Overall, these studies suggest that - Chinese qigong exercise seems to be an optimal option for patients with chronic - heart diseases who were unable to engage in other forms of physical activity; - however, its efficacy and effectiveness in cardiac rehabilitation programs should - be further tested. -FAU - Chan, Cecilia Lai-Wan -AU - Chan CL -AD - Centre on Behavioral Health, University of Hong Kong, 5 Sassoon Road, Pokfulam, - Hong Kong SAR, China. -FAU - Wang, Chong-Wen -AU - Wang CW -FAU - Ho, Rainbow Tin-Hung -AU - Ho RT -FAU - Ho, Andy Hau-Yan -AU - Ho AH -FAU - Ziea, Eric Tat-Chi -AU - Ziea ET -FAU - Taam Wong, Vivian Chi-Woon -AU - Taam Wong VC -FAU - Ng, Siu-Man -AU - Ng SM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - Singapore -TA - Am J Chin Med -JT - The American journal of Chinese medicine -JID - 7901431 -SB - IM -MH - *Breathing Exercises -MH - Clinical Trials as Topic -MH - Heart/physiopathology -MH - Heart Diseases/physiopathology/*rehabilitation -MH - Humans -EDAT- 2012/03/16 06:00 -MHDA- 2012/07/11 06:00 -CRDT- 2012/03/16 06:00 -PHST- 2012/03/16 06:00 [entrez] -PHST- 2012/03/16 06:00 [pubmed] -PHST- 2012/07/11 06:00 [medline] -AID - S0192415X12500206 [pii] -AID - 10.1142/S0192415X12500206 [doi] -PST - ppublish -SO - Am J Chin Med. 2012;40(2):255-67. doi: 10.1142/S0192415X12500206. - -PMID- 22621692 -OWN - NLM -STAT- MEDLINE -DCOM- 20120924 -LR - 20220716 -IS - 1179-1950 (Electronic) -IS - 0012-6667 (Linking) -VI - 72 -IP - 8 -DP - 2012 May 28 -TI - Epidemiology and management of Kawasaki disease. -PG - 1029-38 -LID - 10.2165/11631440-000000000-00000 [doi] -AB - Kawasaki disease (KD) is an acute systemic vasculitis affecting young children - and is rising in incidence worldwide. It is most common in children <5 years of - age, males and those of Asian ethnicity. It is an important cause of acquired - heart disease in children. Standard treatment with high-dose aspirin - (acetylsalicylic acid; ASA) and intravenous immune globulin (IVIG) has been shown - to decrease the rate of coronary artery aneurysm development. Anti-coagulation - has an important place in the management of KD, although guidance based on - evidence is lacking. Treatment of refractory KD is an area under intense study - and may include IVIG, corticosteroids and/or tumour necrosis factor (TNF)-α - inhibitors among immunosuppressive agents. Acute complications of KD include - myocarditis/KD shock syndrome and macrophage activation syndrome, which - necessitate appropriate awareness in order to initiate proper management. -FAU - Luca, Nadia J C -AU - Luca NJ -AD - Department of Pediatrics, University of Toronto, Toronto, ON, Canada. -FAU - Yeung, Rae S M -AU - Yeung RS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - New Zealand -TA - Drugs -JT - Drugs -JID - 7600076 -SB - IM -MH - Animals -MH - Child -MH - Disease Management -MH - Female -MH - Humans -MH - Male -MH - Mucocutaneous Lymph Node Syndrome/*epidemiology/*therapy -MH - Randomized Controlled Trials as Topic -EDAT- 2012/05/25 06:00 -MHDA- 2012/09/25 06:00 -CRDT- 2012/05/25 06:00 -PHST- 2012/05/25 06:00 [entrez] -PHST- 2012/05/25 06:00 [pubmed] -PHST- 2012/09/25 06:00 [medline] -AID - 2 [pii] -AID - 10.2165/11631440-000000000-00000 [doi] -PST - ppublish -SO - Drugs. 2012 May 28;72(8):1029-38. doi: 10.2165/11631440-000000000-00000. - -PMID- 21884686 -OWN - NLM -STAT- MEDLINE -DCOM- 20120325 -LR - 20250529 -IS - 1873-3492 (Electronic) -IS - 0009-8981 (Linking) -VI - 413 -IP - 1-2 -DP - 2012 Jan 18 -TI - Toll-like receptors and macrophage activation in atherosclerosis. -PG - 3-14 -LID - 10.1016/j.cca.2011.08.021 [doi] -AB - Atherosclerosis is a multi-factorial inflammatory disease and is the primary - initiator of coronary artery and cerebrovascular disease. Initially believed to - be exclusively lipid-driven, recent evidence demonstrates that inflammation is a - significant driving force of the disease. Cellular components of innate immunity, - for example monocytes and macrophages, play a predominant role in - atherosclerosis. Toll-like receptors (TLRs) are the most characterised innate - immune receptors and recent evidence demonstrates an important role in - atherogenesis. Engagement of TLRs results in the transcription of - pro-inflammatory cytokines, foam cell formation and activation of adaptive - immunity. Recently they have also been implicated in protection from vascular - disease. In this review, we detail the role of the innate immune system, - specifically macrophages and TLR signalling, in atherosclerosis and acute - cardiovascular complications, and thereby identify the potential of TLRs to act - as therapeutic targets. -CI - Copyright © 2011 Elsevier B.V. All rights reserved. -FAU - Seneviratne, Anusha N -AU - Seneviratne AN -AD - Kennedy Institute of Rheumatology, Faculty of Medicine, Imperial College, London, - United Kingdom. -FAU - Sivagurunathan, Bawani -AU - Sivagurunathan B -FAU - Monaco, Claudia -AU - Monaco C -LA - eng -GR - PG/11/46/28979/BHF_/British Heart Foundation/United Kingdom -GR - ARC_/Arthritis Research UK/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110822 -PL - Netherlands -TA - Clin Chim Acta -JT - Clinica chimica acta; international journal of clinical chemistry -JID - 1302422 -RN - 0 (Toll-Like Receptors) -SB - IM -MH - Atherosclerosis/*immunology -MH - Humans -MH - Immunity, Innate -MH - *Macrophage Activation -MH - Toll-Like Receptors/*physiology -EDAT- 2011/09/03 06:00 -MHDA- 2012/03/27 06:00 -CRDT- 2011/09/03 06:00 -PHST- 2011/05/24 00:00 [received] -PHST- 2011/07/29 00:00 [revised] -PHST- 2011/08/12 00:00 [accepted] -PHST- 2011/09/03 06:00 [entrez] -PHST- 2011/09/03 06:00 [pubmed] -PHST- 2012/03/27 06:00 [medline] -AID - S0009-8981(11)00469-4 [pii] -AID - 10.1016/j.cca.2011.08.021 [doi] -PST - ppublish -SO - Clin Chim Acta. 2012 Jan 18;413(1-2):3-14. doi: 10.1016/j.cca.2011.08.021. Epub - 2011 Aug 22. - -PMID- 21523916 -OWN - NLM -STAT- MEDLINE -DCOM- 20110919 -LR - 20151119 -IS - 1862-8354 (Electronic) -IS - 1862-8346 (Linking) -VI - 5 -IP - 5-6 -DP - 2011 Jun -TI - Urinary proteomics in cardiovascular disease: Achievements, limits and hopes. -PG - 222-32 -LID - 10.1002/prca.201000125 [doi] -AB - Cardiovascular disease (CVD) is the major cause of mortality and morbidity - worldwide. Diagnosis of CVD and risk stratification of patients with CVD remains - challenging despite the availability of a wealth of non-invasive and invasive - tests. Clinical proteomics analyses a large number of peptides and proteins in - biofluids. For clinical applications, the urinary proteome appears particularly - attractive due to the relative low complexity compared with the plasma proteome - and the noninvasive collection of urine. In this article, we review the results - from pilot studies into urinary proteomics of coronary artery disease and discuss - the potential of urinary proteomics in the context of pathogenesis of CVD. -CI - Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. -FAU - Delles, Christian -AU - Delles C -AD - Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary - and Life Sciences, University of Glasgow, Glasgow, UK. - christian.delles@glasgow.ac.uk -FAU - Diez, Javier -AU - Diez J -FAU - Dominiczak, Anna F -AU - Dominiczak AF -LA - eng -GR - BHF RG/07/005/23633/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110427 -PL - Germany -TA - Proteomics Clin Appl -JT - Proteomics. Clinical applications -JID - 101298608 -RN - 0 (Biomarkers) -SB - IM -MH - Animals -MH - Biomarkers/urine -MH - Cardiovascular Diseases/diagnosis/pathology/therapy/*urine -MH - Disease Susceptibility -MH - Humans -MH - Proteomics/*methods -MH - Treatment Outcome -MH - *Urine -EDAT- 2011/04/28 06:00 -MHDA- 2011/09/20 06:00 -CRDT- 2011/04/28 06:00 -PHST- 2010/10/26 00:00 [received] -PHST- 2010/11/29 00:00 [revised] -PHST- 2010/12/15 00:00 [accepted] -PHST- 2011/04/28 06:00 [entrez] -PHST- 2011/04/28 06:00 [pubmed] -PHST- 2011/09/20 06:00 [medline] -AID - 10.1002/prca.201000125 [doi] -PST - ppublish -SO - Proteomics Clin Appl. 2011 Jun;5(5-6):222-32. doi: 10.1002/prca.201000125. Epub - 2011 Apr 27. - -PMID- 17157495 -OWN - NLM -STAT- MEDLINE -DCOM- 20070420 -LR - 20161124 -IS - 0958-1669 (Print) -IS - 0958-1669 (Linking) -VI - 18 -IP - 1 -DP - 2007 Feb -TI - Imaging myocardial metabolism. -PG - 52-9 -AB - The prevalence of coronary artery disease and heart failure is increasing in - modern industrialized countries, fueling the search for novel therapies. Because - metabolism and function in the heart are inextricably linked, energy substrate - metabolism has provided a potential target for novel therapies and the - development of technologies to image myocardial metabolism has been crucial in - establishing new therapeutic approaches. Nuclear imaging probes have been used to - successfully evaluate aerobic fatty acid metabolism, anaerobic glucose - metabolism, and oxidative metabolism and can be used for the accurate, sensitive, - and physiological evaluation of therapeutic effects. More recently, with the - advent of stem-cell technologies, imaging approaches have been employed to track - the fate of stem cells and to monitor the success of these treatments. In the - future, our ability to image myocardial metabolism is likely to assist the - development of other new therapies to improve the function of the failing heart. -FAU - Yoshinaga, Keiichiro -AU - Yoshinaga K -AD - Department of Molecular Imaging, Hokkaido University Graduate School of Medicine, - Sapporo, Hokkaido, Japan. -FAU - Tamaki, Nagara -AU - Tamaki N -LA - eng -PT - Journal Article -PT - Review -DEP - 20061208 -PL - England -TA - Curr Opin Biotechnol -JT - Current opinion in biotechnology -JID - 9100492 -RN - 0 (Fatty Acids) -RN - 0 (Fluorine Radioisotopes) -RN - 0 (Iodine Radioisotopes) -RN - 0 (Iodobenzenes) -RN - 0 (Radiopharmaceuticals) -RN - 0J7USQ749M (iodofiltic acid) -RN - 0Z5B2CJX4D (Fluorodeoxyglucose F18) -RN - IY9XDZ35W2 (Glucose) -RN - PQ6CK8PD0R (Ascorbic Acid) -SB - IM -MH - Ascorbic Acid/metabolism -MH - Fatty Acids -MH - Fluorine Radioisotopes -MH - Fluorodeoxyglucose F18 -MH - Glucose/metabolism -MH - Heart Diseases/diagnostic imaging/metabolism -MH - Humans -MH - Iodine Radioisotopes -MH - Iodobenzenes -MH - Myocardium/*metabolism -MH - *Positron-Emission Tomography -MH - Radiopharmaceuticals -MH - *Tomography, Emission-Computed, Single-Photon -RF - 38 -EDAT- 2006/12/13 09:00 -MHDA- 2007/04/21 09:00 -CRDT- 2006/12/13 09:00 -PHST- 2006/11/03 00:00 [received] -PHST- 2006/11/15 00:00 [revised] -PHST- 2006/11/28 00:00 [accepted] -PHST- 2006/12/13 09:00 [pubmed] -PHST- 2007/04/21 09:00 [medline] -PHST- 2006/12/13 09:00 [entrez] -AID - S0958-1669(06)00167-4 [pii] -AID - 10.1016/j.copbio.2006.11.003 [doi] -PST - ppublish -SO - Curr Opin Biotechnol. 2007 Feb;18(1):52-9. doi: 10.1016/j.copbio.2006.11.003. - Epub 2006 Dec 8. - -PMID- 19178129 -OWN - NLM -STAT- MEDLINE -DCOM- 20090609 -LR - 20181023 -IS - 1175-3277 (Print) -IS - 1175-3277 (Linking) -VI - 9 -IP - 1 -DP - 2009 -TI - Management of angina pectoris: the role of spinal cord stimulation. -PG - 17-28 -LID - 10.2165/00129784-200909010-00003 [doi] -AB - Progress in prevention as well as drug and interventional therapy has improved - the prognosis of patients with cardiovascular disorders. Many patients at risk - have advanced coronary artery disease (CAD), have had multiple coronary - interventions, and present with significant co-morbidity. Despite adequate risk - factor modulation and often several revascularization procedures, some of these - patients still have refractory angina pectoris. Apart from advanced CAD and - insufficient collateralization, the cause is often endothelial dysfunction. For - this situation, one treatment option is neuromodulation. Controlled studies - suggest that, in patients with chronic refractory angina pectoris, spinal cord - stimulation (SCS) provides a relief from symptoms equivalent to that provided by - surgical therapy, but with fewer complications and lower rehospitalization rates. - SCS may result in significant long-term pain relief with improved quality of - life. In patients with refractory angina undergoing SCS, some studies have shown - not only a symptomatic improvement, but also a decrease in myocardial ischemia - and an increase in coronary blood flow. Discussion is ongoing as to whether this - is a direct effect on parasympathetic vascodilation or merely a secondary - phenomenon resulting from increased physical activity following an improvement in - clinical symptoms. Results from nuclear medical studies have sparked discussion - about improved endothelial function and increased collateralization. SCS is a - safe treatment option for patients with refractory angina pectoris, and its - long-term effects are evident. It is a procedure without significant - complications that is easy to tolerate. SCS does not interact with pacemakers, - provided that strict bipolar right-ventricular sensing is used. Use in patients - with implanted cardioverter defibrillators is under discussion. Individual - testing is mandatory in order to assess optimal safety in each patient. -FAU - Eckert, Siegfried -AU - Eckert S -AD - Department of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, - Ruhr-University Bochum, Bad Oeynhausen, Germany. seckert@hdz-nrw.de -FAU - Horstkotte, Dieter -AU - Horstkotte D -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -SB - IM -MH - Angina Pectoris/physiopathology/*therapy -MH - Cerebrovascular Circulation/physiology -MH - Collateral Circulation/physiology -MH - Coronary Circulation/physiology -MH - Electric Stimulation Therapy/adverse effects/*methods -MH - Endothelium, Vascular/metabolism/*physiopathology -MH - Humans -MH - Recurrence -MH - Spinal Cord/*physiopathology -RF - 88 -EDAT- 2009/01/31 09:00 -MHDA- 2009/06/10 09:00 -CRDT- 2009/01/31 09:00 -PHST- 2009/01/31 09:00 [entrez] -PHST- 2009/01/31 09:00 [pubmed] -PHST- 2009/06/10 09:00 [medline] -AID - 3 [pii] -AID - 10.2165/00129784-200909010-00003 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2009;9(1):17-28. doi: 10.2165/00129784-200909010-00003. - -PMID- 19914093 -OWN - NLM -STAT- MEDLINE -DCOM- 20110225 -LR - 20101115 -IS - 1879-1336 (Electronic) -IS - 1054-8807 (Linking) -VI - 19 -IP - 6 -DP - 2010 Nov-Dec -TI - Post-irradiation pericardial malignant mesothelioma: an autopsy case and review - of the literature. -PG - 377-9 -LID - 10.1016/j.carpath.2009.08.003 [doi] -AB - We report a case of a malignant pericardial mesothelioma of the epithelioid type - in a 39-year-old man. He had a history of nodular sclerosing Hodgkin's disease - treated with irradiation of the cervical and mediastinal regions 24 years before, - and of infarction of the anterior wall of the left ventricle, after which a - percutaneous coronary intervention was carried out 7 years previously. He was - admitted to a cardiology unit with progressive dyspnea. On examination, a - hemorrhagic pericardial fluid collection of 600 ml was detected which was - successfully drained. On the next day, the patient developed an electromechanical - dissociation suggesting a pericardial tamponade, which was followed by - circulatory arrest. At autopsy, the pericardial sac was found to contain 300 ml - of partly clotted blood. The epicardial surface showed a diffuse thickening, - suggesting a chronic fibrous pericarditis without a macroscopically evident - distinct tumor mass. A rupture measuring 0.4 cm in diameter was detected in the - right ventricular free wall, 1 cm below the level of the tricuspid valve. The - diagnosis of a diffusely growing, malignant mesothelioma of the epithelioid type - was made on the basis of histological and immunohistochemical examination of the - thickened pericardium. -CI - Copyright © 2010 Elsevier Inc. All rights reserved. -FAU - Bendek, Matyas -AU - Bendek M -AD - Institute of Pathology Ludwig-Aschoff-Haus, Freiburg University Medical Center, - Freiburg, Germany. bendekm@gmail.com -FAU - Ferenc, Miroslaw -AU - Ferenc M -FAU - Freudenberg, Nikolaus -AU - Freudenberg N -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20091114 -PL - United States -TA - Cardiovasc Pathol -JT - Cardiovascular pathology : the official journal of the Society for Cardiovascular - Pathology -JID - 9212060 -SB - IM -MH - Adult -MH - Autopsy -MH - Cardiac Tamponade/etiology -MH - Fatal Outcome -MH - Heart Neoplasms/*etiology/pathology -MH - Hodgkin Disease/*radiotherapy -MH - Humans -MH - Immunohistochemistry -MH - Male -MH - Mesothelioma/*etiology/pathology -MH - Neoplasms, Radiation-Induced/*etiology/pathology -MH - Pericardial Effusion/etiology -MH - Pericardium/pathology -MH - Radiotherapy/adverse effects -MH - Shock/etiology -EDAT- 2009/11/17 06:00 -MHDA- 2011/02/26 06:00 -CRDT- 2009/11/17 06:00 -PHST- 2009/07/06 00:00 [received] -PHST- 2009/08/26 00:00 [accepted] -PHST- 2009/11/17 06:00 [entrez] -PHST- 2009/11/17 06:00 [pubmed] -PHST- 2011/02/26 06:00 [medline] -AID - S1054-8807(09)00097-0 [pii] -AID - 10.1016/j.carpath.2009.08.003 [doi] -PST - ppublish -SO - Cardiovasc Pathol. 2010 Nov-Dec;19(6):377-9. doi: 10.1016/j.carpath.2009.08.003. - Epub 2009 Nov 14. - -PMID- 20118395 -OWN - NLM -STAT- MEDLINE -DCOM- 20100225 -LR - 20220330 -IS - 1942-5546 (Electronic) -IS - 0025-6196 (Print) -IS - 0025-6196 (Linking) -VI - 85 -IP - 2 -DP - 2010 Feb -TI - Chronic heart failure: contemporary diagnosis and management. -PG - 180-95 -LID - 10.4065/mcp.2009.0494 [doi] -AB - Chronic heart failure (CHF) remains the only cardiovascular disease with an - increasing hospitalization burden and an ongoing drain on health care - expenditures. The prevalence of CHF increases with advancing life span, with - diastolic heart failure predominating in the elderly population. Primary - prevention of coronary artery disease and risk factor management via aggressive - blood pressure control are central in preventing new occurrences of left - ventricular dysfunction. Optimal therapy for CHF involves identification and - correction of potentially reversible precipitants, target-dose titration of - medical therapy, and management of hospitalizations for decompensation. The - etiological phenotype, absolute decrease in left ventricular ejection fraction - and a widening of QRS duration on electrocardiography, is commonly used to - identify patients at increased risk of progression of heart failure and sudden - death who may benefit from prophylactic implantable cardioverter-defibrillator - placement with or without cardiac resynchronization therapy. Patients who - transition to advanced stages of disease despite optimal traditional medical and - device therapy may be candidates for hemodynamically directed approaches such as - a left ventricular assist device; in selected cases, listing for cardiac - transplant may be warranted. -FAU - Ramani, Gautam V -AU - Ramani GV -AD - University of Maryland School of Medicine, Baltimore, USA. -FAU - Uber, Patricia A -AU - Uber PA -FAU - Mehra, Mandeep R -AU - Mehra MR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Mayo Clin Proc -JT - Mayo Clinic proceedings -JID - 0405543 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Antihypertensive Agents) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Cardiotonic Agents) -RN - 0 (Vasodilator Agents) -SB - IM -CIN - Mayo Clin Proc. 2010 Jul;85(7):693; author reply 693. doi: 10.4065/mcp.2010.0185. - PMID: 20592175 -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Antihypertensive Agents/therapeutic use -MH - Calcium Channel Blockers/therapeutic use -MH - Cardiotonic Agents/therapeutic use -MH - Chronic Disease -MH - Defibrillators, Implantable -MH - Health Expenditures/trends -MH - Heart Failure/*diagnosis/economics/epidemiology/etiology/*therapy -MH - Heart Transplantation -MH - Heart-Assist Devices -MH - Hospitalization/trends -MH - Humans -MH - Mass Screening -MH - Prevalence -MH - Primary Prevention -MH - Prognosis -MH - Vasodilator Agents/therapeutic use -PMC - PMC2813829 -EDAT- 2010/02/02 06:00 -MHDA- 2010/02/26 06:00 -PMCR- 2010/08/01 -CRDT- 2010/02/02 06:00 -PHST- 2010/02/02 06:00 [entrez] -PHST- 2010/02/02 06:00 [pubmed] -PHST- 2010/02/26 06:00 [medline] -PHST- 2010/08/01 00:00 [pmc-release] -AID - S0025-6196(11)60393-5 [pii] -AID - 10.4065/mcp.2009.0494 [doi] -PST - ppublish -SO - Mayo Clin Proc. 2010 Feb;85(2):180-95. doi: 10.4065/mcp.2009.0494. - -PMID- 23391667 -OWN - NLM -STAT- MEDLINE -DCOM- 20130409 -LR - 20181202 -IS - 1941-9260 (Electronic) -IS - 0032-5481 (Linking) -VI - 125 -IP - 1 -DP - 2013 Jan -TI - Statin wars: the heavyweight match--atorvastatin versus rosuvastatin for the - treatment of atherosclerosis, heart failure, and chronic kidney disease. -PG - 7-16 -LID - 10.3810/pgm.2013.01.2620 [doi] -AB - Statins are a standard of care in many clinical settings, especially for - dyslipidemia management, and are used for the primary and secondary prevention of - cardiovascular disease. Importantly, not all statins are born equal. The statin - class consists of a number of heterogenous drugs, which vary in properties such - as potency in lowering low-density lipoprotein cholesterol levels, lipophilicity, - renoprotection, increasing high-density lipoprotein cholesterol levels, lowering - triglyceride levels, and effects on glucose metabolism and myocardial function. - It remains unclear whether these differences significantly impact clinical - outcomes or if 1 statin should be preferred over another. This review summarizes - the properties of the 2 most potent statins available (atorvastatin and - rosuvastatin), as well as assesses the comparative experimental and clinical - trials that have been conducted on these 2 agents. We believe that the available - body of evidence indicates that atorvastatin may have several advantages over - rosuvastatin, despite the latter's greater potency, suggesting that atorvastatin - should be the potent statin of choice, especially in treating patients with renal - impairment or heart failure with concomitant coronary artery disease. The recent - availability of atorvastatin as a generic option gives this drug another - practical and compelling advantage over rosuvastatin. -FAU - DiNicolantonio, James J -AU - DiNicolantonio JJ -AD - Wegmans Pharmacy, Ithaca, NY, USA. jjdinicol@gmail.com -FAU - Lavie, Carl J -AU - Lavie CJ -FAU - Serebruany, Victor L -AU - Serebruany VL -FAU - O'Keefe, James H -AU - O'Keefe JH -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Postgrad Med -JT - Postgraduate medicine -JID - 0401147 -RN - 0 (Fluorobenzenes) -RN - 0 (Heptanoic Acids) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Pyrimidines) -RN - 0 (Pyrroles) -RN - 0 (Sulfonamides) -RN - 83MVU38M7Q (Rosuvastatin Calcium) -RN - A0JWA85V8F (Atorvastatin) -SB - IM -MH - Atherosclerosis/*drug therapy -MH - Atorvastatin -MH - Fluorobenzenes/*therapeutic use -MH - Heart Failure/*drug therapy -MH - Heptanoic Acids/*therapeutic use -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Pyrimidines/*therapeutic use -MH - Pyrroles/*therapeutic use -MH - Renal Insufficiency, Chronic/*drug therapy -MH - Rosuvastatin Calcium -MH - Sulfonamides/*therapeutic use -EDAT- 2013/02/09 06:00 -MHDA- 2013/04/10 06:00 -CRDT- 2013/02/09 06:00 -PHST- 2013/02/09 06:00 [entrez] -PHST- 2013/02/09 06:00 [pubmed] -PHST- 2013/04/10 06:00 [medline] -AID - 10.3810/pgm.2013.01.2620 [doi] -PST - ppublish -SO - Postgrad Med. 2013 Jan;125(1):7-16. doi: 10.3810/pgm.2013.01.2620. - -PMID- 23666251 -OWN - NLM -STAT- MEDLINE -DCOM- 20141030 -LR - 20220331 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Print) -IS - 0195-668X (Linking) -VI - 35 -IP - 10 -DP - 2014 Mar -TI - Cardiovascular complications of radiation therapy for thoracic malignancies: the - role for non-invasive imaging for detection of cardiovascular disease. -PG - 612-23 -LID - 10.1093/eurheartj/eht114 [doi] -AB - Radiation exposure to the thorax is associated with substantial risk for the - subsequent development of cardiovascular disease. Thus, the increasing role of - radiation therapy in the contemporary treatment of cancer, combined with - improving survival rates of patients undergoing this therapy, contributes to a - growing population at risk of cardiovascular morbidity and mortality. Associated - cardiovascular injuries include pericardial disease, coronary artery disease, - valvular disease, conduction disease, cardiomyopathy, and medium and large vessel - vasculopathy-any of which can occur at varying intervals following irradiation. - Higher radiation doses, younger age at the time of irradiation, longer intervals - from the time of radiation, and coexisting cardiovascular risk factors all - predispose to these injuries. The true incidence of radiation-related - cardiovascular disease remains uncertain due to lack of large multicentre studies - with a sufficient duration of cardiovascular follow-up. There are currently no - consensus guidelines available to inform the optimal approach to cardiovascular - surveillance of recipients of thoracic radiation. Therefore, we review the - cardiovascular consequences of radiation therapy and focus on the potential role - of non-invasive cardiovascular imaging in the assessment and management of - radiation-related cardiovascular disease. In doing so, we highlight - characteristics that can be used to identify individuals at risk for developing - post-radiation cardiovascular disease and propose an imaging-based algorithm for - their clinical surveillance. -FAU - Groarke, John D -AU - Groarke JD -AD - Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's - Hospital, Boston, MA 02115, USA. -FAU - Nguyen, Paul L -AU - Nguyen PL -FAU - Nohria, Anju -AU - Nohria A -FAU - Ferrari, Roberto -AU - Ferrari R -FAU - Cheng, Susan -AU - Cheng S -FAU - Moslehi, Javid -AU - Moslehi J -LA - eng -GR - K08-HL097031/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130510 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -SB - IM -MH - Diagnostic Imaging/methods -MH - Heart Diseases/diagnosis/*etiology -MH - Humans -MH - Patient Care Planning -MH - Preoperative Care/methods -MH - Radiation Dosage -MH - Radiation Injuries/diagnosis/*etiology -MH - Thoracic Neoplasms/*radiotherapy -MH - Vascular Diseases/diagnosis/*etiology -PMC - PMC3945797 -OTO - NOTNLM -OT - Non-invasive imaging -OT - Radiation therapy -EDAT- 2013/05/15 06:00 -MHDA- 2014/10/31 06:00 -PMCR- 2015/03/07 -CRDT- 2013/05/14 06:00 -PHST- 2013/05/14 06:00 [entrez] -PHST- 2013/05/15 06:00 [pubmed] -PHST- 2014/10/31 06:00 [medline] -PHST- 2015/03/07 00:00 [pmc-release] -AID - eht114 [pii] -AID - 10.1093/eurheartj/eht114 [doi] -PST - ppublish -SO - Eur Heart J. 2014 Mar;35(10):612-23. doi: 10.1093/eurheartj/eht114. Epub 2013 May - 10. - -PMID- 21889018 -OWN - NLM -STAT- MEDLINE -DCOM- 20111031 -LR - 20161125 -IS - 1557-8275 (Electronic) -IS - 0033-8389 (Linking) -VI - 49 -IP - 5 -DP - 2011 Sep -TI - Cardiac MDCT in children: CT technology overview and interpretation. -PG - 997-1010 -LID - 10.1016/j.rcl.2011.06.001 [doi] -AB - Cardiac multidetector computed tomography (MDCT) for congenital heart disease is - a useful, rapid, and noninvasive imaging technique bridging the gaps between - echocardiography, cardiac catheterization, and cardiac MRI. Fast scan speed and - greater anatomic coverage, combined with flexible ECG-synchronized scans and a - low radiation dose, are critical for improving the image quality of cardiac MDCT - and minimizing patient risk. Current MDCT techniques can accurately evaluate - extracardiac great vessels, lungs, and airways, as well as coronary arteries and - intracardiac structures. Radiologists who perform cardiac MDCT in children should - be familiarized with optimal cardiac computed tomography (CT) scan techniques and - characteristic cardiac CT scan imaging findings. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Goo, Hyun Woo -AU - Goo HW -AD - Department of Radiology and Research Institute of Radiology, Asan Medical Center, - University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, - South Korea. hwgoo@amc.seoul.kr -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Radiol Clin North Am -JT - Radiologic clinics of North America -JID - 0123703 -SB - IM -MH - Adolescent -MH - Adult -MH - Child -MH - Child, Preschool -MH - Electrocardiography/methods -MH - Female -MH - Heart/diagnostic imaging -MH - Heart Defects, Congenital/*diagnostic imaging -MH - Humans -MH - Imaging, Three-Dimensional/methods -MH - Infant -MH - Infant, Newborn -MH - Male -MH - Tomography, X-Ray Computed/*methods -MH - Young Adult -EDAT- 2011/09/06 06:00 -MHDA- 2011/11/01 06:00 -CRDT- 2011/09/06 06:00 -PHST- 2011/09/06 06:00 [entrez] -PHST- 2011/09/06 06:00 [pubmed] -PHST- 2011/11/01 06:00 [medline] -AID - S0033-8389(11)00071-6 [pii] -AID - 10.1016/j.rcl.2011.06.001 [doi] -PST - ppublish -SO - Radiol Clin North Am. 2011 Sep;49(5):997-1010. doi: 10.1016/j.rcl.2011.06.001. - -PMID- 16498509 -OWN - NLM -STAT- MEDLINE -DCOM- 20070920 -LR - 20190608 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Print) -IS - 0828-282X (Linking) -VI - 22 Suppl B -IP - Suppl B -DP - 2006 Feb -TI - Matrix metalloproteinases in cardiovascular disease. -PG - 25B-30B -AB - Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that are - regulated by inflammatory signals to mediate changes in extracellular matrix. - Members of the MMP family share sequence homology, act on interstitial protein - substrates, acutely participate in inflammatory processes and chronically mediate - tissue remodelling. MMPs are important in vascular remodelling, not only in the - overall vasculature architecture but also, more importantly, in the advancing - atherosclerotic plaque. MMP activation modifies the architecture of the plaque - and may directly participate in the process of plaque rupture. MMPs also - participate in cardiac remodelling following myocardial infarction and - development of dilated cardiomyopathy. Soluble MMPs are now potential biomarkers - in delineating cardiovascular risk for plaque rupture and coronary risk. They - also constitute innovative direct or indirect targets to modify cardiovascular - tissue remodelling in atherosclerosis and heart failure. -FAU - Liu, Peter -AU - Liu P -AD - Heart & Stroke/Richard Lewar Centre of Excellence, and the Department of - Physiology, Toronto General Hospital, Toronto, Ontario. peter.liu@utoronto.ca -FAU - Sun, Mei -AU - Sun M -FAU - Sader, Sawsan -AU - Sader S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -RN - EC 3.4.24.- (Matrix Metalloproteinases) -SB - IM -MH - Animals -MH - Atherosclerosis/*physiopathology -MH - Cardiovascular Diseases/*physiopathology -MH - Enzyme Activation -MH - Extracellular Matrix/physiology -MH - Heart Failure/physiopathology -MH - Humans -MH - Matrix Metalloproteinases/*physiology -MH - Myocardium/pathology -MH - Ventricular Remodeling/physiology -PMC - PMC2780831 -EDAT- 2006/02/25 09:00 -MHDA- 2007/09/21 09:00 -PMCR- 2007/02/01 -CRDT- 2006/02/25 09:00 -PHST- 2006/02/25 09:00 [pubmed] -PHST- 2007/09/21 09:00 [medline] -PHST- 2006/02/25 09:00 [entrez] -PHST- 2007/02/01 00:00 [pmc-release] -AID - S0828-282X(06)70983-7 [pii] -AID - cjc22025b [pii] -AID - 10.1016/s0828-282x(06)70983-7 [doi] -PST - ppublish -SO - Can J Cardiol. 2006 Feb;22 Suppl B(Suppl B):25B-30B. doi: - 10.1016/s0828-282x(06)70983-7. - -PMID- 18478818 -OWN - NLM -STAT- MEDLINE -DCOM- 20080710 -LR - 20121115 -IS - 0094-6354 (Print) -IS - 0094-6354 (Linking) -VI - 76 -IP - 2 -DP - 2008 Apr -TI - Mitral valve replacement: a case report. -PG - 125-9 -AB - Mitral regurgitation is commonly encountered in anesthesia clinical practice. - Knowledge of the pathophysiology and proper anesthetic management is crucial to - achieving optimal outcomes. Surgical advancements and early intervention have led - to improved outcomes. An ASA class III, 58-year-old woman with mitral - regurgitation secondary to rheumatic fever, presented for repair or replacement - of the mitral valve. A graded induction with low-dose narcotic, isoflurane, and - phenylephrine was required to maintain acceptable cardiovascular parameters - during induction and throughout the case. Additional interventions included - adequate preload, normal heart rate, and decreased afterload, to maintain a mean - arterial pressure of 65 mm Hg. Ampicillin and gentamicin were administered - according to American Heart Association guidelines for prophylactic management - against subacute bacterial endocarditis. Milrinone and epinephrine were required - for inotropic support until the left ventricle recovered from ischemic time. - Milrinone was an ideal inotrope in this case, as its vasodilator properties - allowed an increase in forward flow with minimal impact on pulmonary - hypertension. Goals for the anesthetist include preservation of forward flow with - minimal regurgitation and decreased pulmonary congestion. Invasive monitoring and - transesophageal echocardiography have improved diagnostics and anesthetic - management. -FAU - Reckard, Derek -AU - Reckard D -AD - University of Pittsburgh School of Nursing, Nurse Anesthesia Program, - Pennsylvania, USA. reckardda@upmc.edu -FAU - Cipcic, Eric -AU - Cipcic E -FAU - Mackin, Carol -AU - Mackin C -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - AANA J -JT - AANA journal -JID - 0431420 -MH - *Anesthesia, Inhalation/methods/nursing -MH - Cardiac Catheterization -MH - Cardiopulmonary Bypass -MH - Coronary Angiography -MH - Echocardiography, Doppler -MH - Female -MH - Heart Failure/etiology -MH - *Heart Valve Prosthesis Implantation/methods/nursing -MH - Humans -MH - *Intraoperative Care/methods/nursing -MH - Middle Aged -MH - Mitral Valve Insufficiency/diagnosis/etiology/*surgery -MH - Monitoring, Intraoperative/methods/nursing -MH - *Nurse Anesthetists -MH - Rheumatic Heart Disease/complications -MH - Severity of Illness Index -RF - 11 -EDAT- 2008/05/16 09:00 -MHDA- 2008/07/11 09:00 -CRDT- 2008/05/16 09:00 -PHST- 2008/05/16 09:00 [pubmed] -PHST- 2008/07/11 09:00 [medline] -PHST- 2008/05/16 09:00 [entrez] -PST - ppublish -SO - AANA J. 2008 Apr;76(2):125-9. - -PMID- 16501630 -OWN - NLM -STAT- MEDLINE -DCOM- 20061108 -LR - 20121115 -IS - 1743-4297 (Print) -IS - 1743-4297 (Linking) -VI - 3 Suppl 1 -DP - 2006 Mar -TI - Surgical and catheter delivery of autologous myoblasts in patients with - congestive heart failure. -PG - S42-5 -AB - Autologous skeletal myoblast (ASM) transplantation is being explored as a - possible therapy for patients who have suffered a myocardial infarction. Our - initial experience with direct injection during coronary artery bypass grafting - demonstrated that this method of delivery was both feasible and safe. In - addition, proof of concept of the engraftment and survival of ASMs was shown. - However, since many patients who have survived a myocardial infarction are not - candidates for surgery, a less invasive delivery method is preferred. We - implemented a series of translational research steps to bring catheter-based - technology to a clinical application. This included assessing the - biocompatibility of the ASM and a novel needle injection catheter using a - 3-dimensional endoventricular navigation system, the bioretention and - biodistribution of ASMs in a porcine model of myocardial infarction, and the - safety and efficacy of ASM transplantation for cardiac function in the porcine - model. After catheter functionality had been demonstrated, electromechanical - mapping was used to assess the viability in the region of ASM transplantation, - and echocardiography, electrocardiogram, and angiography tests were used to - assess cardiac function 2 months after ASM transplantation. The results from - these preclinical studies were used as a foundation for application of these - concepts to a human clinical trial. Here we review the results from our - preclinical experiments and surgical delivery clinical trial, and describe the - recent clinical studies undertaken to assess the safety and feasibility of - catheter-based ASM transplantation into human subjects. -FAU - Opie, Shaun R -AU - Opie SR -AD - Department of Gene and Cell Research, Arizona Heart Institute, Phoenix, AZ 85006, - USA. -FAU - Dib, Nabil -AU - Dib N -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Nat Clin Pract Cardiovasc Med -JT - Nature clinical practice. Cardiovascular medicine -JID - 101226507 -SB - IM -MH - Animals -MH - *Cardiac Catheterization -MH - Disease Models, Animal -MH - Heart/*physiology -MH - Heart Failure/metabolism/surgery/*therapy -MH - Humans -MH - Myoblasts, Skeletal/metabolism/*transplantation -MH - Randomized Controlled Trials as Topic -MH - *Regeneration -MH - Swine -MH - Transplantation, Autologous -MH - Treatment Outcome -RF - 13 -EDAT- 2006/02/28 09:00 -MHDA- 2006/11/10 09:00 -CRDT- 2006/02/28 09:00 -PHST- 2005/09/06 00:00 [received] -PHST- 2005/10/04 00:00 [accepted] -PHST- 2006/02/28 09:00 [pubmed] -PHST- 2006/11/10 09:00 [medline] -PHST- 2006/02/28 09:00 [entrez] -AID - ncpcardio0399 [pii] -AID - 10.1038/ncpcardio0399 [doi] -PST - ppublish -SO - Nat Clin Pract Cardiovasc Med. 2006 Mar;3 Suppl 1:S42-5. doi: - 10.1038/ncpcardio0399. - -PMID- 23212946 -OWN - NLM -STAT- MEDLINE -DCOM- 20131216 -LR - 20250220 -IS - 1932-8737 (Electronic) -IS - 0160-9289 (Print) -IS - 0160-9289 (Linking) -VI - 36 -IP - 5 -DP - 2013 May -TI - Comparing the new European cardiovascular disease prevention guideline with prior - American Heart Association guidelines: an editorial review. -PG - E1-6 -LID - 10.1002/clc.22079 [doi] -AB - Atherosclerotic heart disease and stroke remain the leading causes of death and - disability worldwide. Cardiovascular disease (CVD) prevention can improve the - well-being of a population and possibly cut downstream healthcare spending, and - must be the centerpiece of any sustainable health economy model. As lifestyle and - CVD risk factors differ among ethnicities, cultures, genders, and age groups, an - accurate risk assessment model is the critical first step for guiding appropriate - use of testing, lifestyle counseling resources, and preventive medications. - Examples of such models include the US Framingham Risk Score and the European - SCORE system. The European Society of Cardiology recently published an updated - set of guidelines on CVD prevention. This review highlights the similarities and - differences between European and US risk assessment models, as well as their - respective recommendations on the use of advanced testing for further risk - reclassification and the appropriate use of medications. In particular, we focus - on head-to-head comparison of the new European guideline with prior American - Heart Association statements (2002, 2010, and 2011) covering risk assessment and - treatment of asymptomatic adults. Despite minor disagreements on the weight of - recommendations in certain areas, such as the use of coronary calcium score and - non-high-density lipoprotein cholesterol in risk assessment, CVD prevention - experts across the 2 continents agree on 1 thing: prevention works in halting the - progression of atherosclerosis and decreasing disease burden over a lifetime. -CI - © 2012 Wiley Periodicals, Inc. -FAU - Ton, Van-Khue -AU - Ton VK -AD - The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, - Baltimore, Maryland, USA. -FAU - Martin, Seth S -AU - Martin SS -FAU - Blumenthal, Roger S -AU - Blumenthal RS -FAU - Blaha, Michael J -AU - Blaha MJ -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -DEP - 20121204 -PL - United States -TA - Clin Cardiol -JT - Clinical cardiology -JID - 7903272 -SB - IM -MH - Humans -MH - *American Heart Association -MH - *Cardiovascular Diseases/diagnosis/epidemiology/prevention & control -MH - Europe -MH - Practice Guidelines as Topic -MH - *Preventive Health Services/standards -MH - Risk Assessment -MH - Risk Factors -MH - Treatment Outcome -MH - United States -PMC - PMC6649576 -EDAT- 2012/12/06 06:00 -MHDA- 2013/12/18 06:00 -PMCR- 2012/12/04 -CRDT- 2012/12/06 06:00 -PHST- 2012/08/20 00:00 [received] -PHST- 2012/10/24 00:00 [revised] -PHST- 2012/12/06 06:00 [entrez] -PHST- 2012/12/06 06:00 [pubmed] -PHST- 2013/12/18 06:00 [medline] -PHST- 2012/12/04 00:00 [pmc-release] -AID - CLC22079 [pii] -AID - 10.1002/clc.22079 [doi] -PST - ppublish -SO - Clin Cardiol. 2013 May;36(5):E1-6. doi: 10.1002/clc.22079. Epub 2012 Dec 4. - -PMID- 20051660 -OWN - NLM -STAT- MEDLINE -DCOM- 20100920 -LR - 20161125 -IS - 1423-0003 (Electronic) -IS - 0304-324X (Linking) -VI - 56 -IP - 4 -DP - 2010 -TI - Cardiac surgery in nonagenarians: single-centre series and review. -PG - 378-84 -LID - 10.1159/000271602 [doi] -AB - BACKGROUND: Cardiac surgery is widely believed to be an excessively high-risk - intervention for very elderly patients with coronary artery or valvular disease. - However, as life expectancy and the prospect of sustained quality of life into - older age increase, this assumption should be challenged so that surgery is not - denied to patients who may derive significant symptomatic benefit with acceptable - levels of operative risk. OBJECTIVE: To evaluate outcomes from cardiac surgery in - nonagenarian patients. DESIGN: Analysis of prospectively collected single-centre - data and review of outcomes reported in the literature. RESULTS: Twenty-three - patients (13 males) aged 90 years or more underwent open cardiac surgery between - 1998 and 2007. Four patients died within 30 days of surgery (surgical mortality - 17.4%) and all-cause in-hospital morbidity was 74%. Actuarial survival at 1 and 5 - years was estimated at 72 and 54%, respectively. Comparison of patients' survival - against age-matched life tables for the English population found a standardised - mortality ratio of 0.57 (95% CI: 0.24-0.99; one-sample log-rank test chi(2) = - 3.93; p < 0.05) representing a significant survival benefit associated with - surgery. The majority of patients reported symptomatic improvement reflected by - significant decreases in angina and dyspnoea scores. Six single-centre series of - nonagenarians and 3 reviews from national databases in the US and UK were - identified in the literature. Pooled surgical mortality was 12.7% (95% CI: - 8.7-17.3%) with no significant heterogeneity (chi(2) = 4.12; p = 0.77; I(2) = 0). - CONCLUSION: Cardiac surgery in the elderly carries higher operative risk than in - younger patients. However, in selected nonagenarians, surgery can be performed - with acceptable morbidity and early mortality, and patients gain significant - symptomatic relief and survival benefit. -CI - Copyright 2009 S. Karger AG, Basel. -FAU - Guilfoyle, Mathew R -AU - Guilfoyle MR -AD - Papworth Hospital, Cambridge, UK. -FAU - Drain, Andrew J -AU - Drain AJ -FAU - Khan, Asmatullah -AU - Khan A -FAU - Ferguson, Jonathan -AU - Ferguson J -FAU - Large, Stephen R -AU - Large SR -FAU - Nashef, Samer A M -AU - Nashef SA -LA - eng -PT - Journal Article -PT - Review -DEP - 20091223 -PL - Switzerland -TA - Gerontology -JT - Gerontology -JID - 7601655 -SB - IM -MH - Age Factors -MH - Aged -MH - Aged, 80 and over -MH - Aortic Valve -MH - Cardiac Surgical Procedures/*mortality -MH - Coronary Artery Bypass/mortality -MH - Female -MH - Heart Valve Prosthesis Implantation/mortality -MH - Humans -MH - Kaplan-Meier Estimate -MH - Male -MH - Prospective Studies -MH - Risk Factors -MH - Treatment Outcome -MH - United Kingdom/epidemiology -RF - 38 -EDAT- 2010/01/07 06:00 -MHDA- 2010/09/21 06:00 -CRDT- 2010/01/07 06:00 -PHST- 2008/11/04 00:00 [received] -PHST- 2009/06/24 00:00 [accepted] -PHST- 2010/01/07 06:00 [entrez] -PHST- 2010/01/07 06:00 [pubmed] -PHST- 2010/09/21 06:00 [medline] -AID - 000271602 [pii] -AID - 10.1159/000271602 [doi] -PST - ppublish -SO - Gerontology. 2010;56(4):378-84. doi: 10.1159/000271602. Epub 2009 Dec 23. - -PMID- 23098790 -OWN - NLM -STAT- MEDLINE -DCOM- 20130415 -LR - 20121026 -IS - 1166-7087 (Print) -IS - 1166-7087 (Linking) -VI - 22 Suppl 2 -DP - 2012 Sep -TI - [Androgen deprivation and cardiovascular risk in prostate cancer treatment]. -PG - S48-54 -LID - S1166-7087(12)70036-2 [pii] -LID - 10.1016/S1166-7087(12)70036-2 [doi] -AB - Androgen suppression clearly increases the occurrence of cardiovascular risk - factors : increased body fat, dyslipidemia and type II diabetes. Thus, several - studies (but not all), showed an increase in coronary artery disease but also of - sudden death and ventricular arrhythmias in relation to androgen deprivation, - even for a short duration. This risk is particularly important in patients with - existing cardiovascular risk factors or a history of heart disease. - Cardiovascular risk should be balanced with the benefit of androgen deprivation - on overall survival, especially when it is proposed in adjuvant setting, combined - with radiotherapy in locally advanced prostate tumors. In practice, it is - recommended that patients be referred to their physician for an evaluation before - starting treatment, then 3 to 6 months after starting treatment, then once a - year. The initial assessment should include: a clinical examination (with - measurement of blood pressure and body index) and laboratory test with full lipid - profile (total cholesterol, HDL and LDL cholesterol, triglycerides) and glucose. - It is also important that patients with heart disease, receive lifestyle advice - and low- dose aspirin (80 mg/day). -CI - Copyright © 2012 Elsevier Masson SAS. All rights reserved. -FAU - Leclercq, C -AU - Leclercq C -AD - Département de Cardiologie et Maladies Vasculaires, CHU Pontchaillou, Rennes, F- - 35033, France. christophe.leclercq@churennes.fr -FAU - Bouchot, O -AU - Bouchot O -FAU - Azzouzi, A-R -AU - Azzouzi AR -FAU - Joly, F -AU - Joly F -FAU - Miaadi, N -AU - Miaadi N -FAU - Pfister, C -AU - Pfister C -FAU - Vincendeau, S -AU - Vincendeau S -FAU - de Crevoisier, R -AU - de Crevoisier R -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Hormonothérapie et risque cardiaque dans le traitement des cancers prostatiques. -PL - France -TA - Prog Urol -JT - Progres en urologie : journal de l'Association francaise d'urologie et de la - Societe francaise d'urologie -JID - 9307844 -RN - 0 (Androgen Antagonists) -SB - IM -MH - Androgen Antagonists/*adverse effects/therapeutic use -MH - Cardiovascular Diseases/*chemically induced/epidemiology -MH - Humans -MH - Male -MH - Prostatic Neoplasms/*drug therapy -MH - Risk -EDAT- 2012/11/01 06:00 -MHDA- 2013/04/16 06:00 -CRDT- 2012/10/27 06:00 -PHST- 2012/10/27 06:00 [entrez] -PHST- 2012/11/01 06:00 [pubmed] -PHST- 2013/04/16 06:00 [medline] -AID - S1166-7087(12)70036-2 [pii] -AID - 10.1016/S1166-7087(12)70036-2 [doi] -PST - ppublish -SO - Prog Urol. 2012 Sep;22 Suppl 2:S48-54. doi: 10.1016/S1166-7087(12)70036-2. - -PMID- 23063140 -OWN - NLM -STAT- MEDLINE -DCOM- 20140422 -LR - 20130902 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 167 -IP - 5 -DP - 2013 Sep 1 -TI - Role of microRNAs in cardiac remodelling: new insights and future perspectives. -PG - 1651-9 -LID - S0167-5273(12)01241-7 [pii] -LID - 10.1016/j.ijcard.2012.09.120 [doi] -AB - Cardiac remodelling is a key process in the progression of cardiovascular - disease, implemented in myocardial infarction, valvular heart disease, - myocarditis, dilated cardiomyopathy, atrial fibrillation and heart failure. - Fibroblasts, extracellular matrix proteins, coronary vasculature, cardiac - myocytes and ionic channels are all involved in this remodelling process. - MicroRNAs (miRNAs) represent a sizable sub-group of small non-coding RNAs, which - degrade or inhibit the translation of their target mRNAs, thus regulating gene - expression and play an important role in a wide range of biologic processes. - Recent studies have reported that miRNAs are aberrantly expressed in the - cardiovascular system under some pathological conditions. Indeed, in vitro and in - vivo models have revealed that miRNAs are essential for cardiac development and - remodelling. Clinically, there is increasing evidence of the potential diagnostic - role of miRNAs as potential diagnostic biomarkers and they may represent a novel - therapeutic target in several cardiovascular disorders. This paper provides an - overview of the impact of several miRNAs in electrical and structural remodelling - of the cardiac tissue, and the diagnostic and therapeutic potential of miRNA in - cardiovascular disease. -CI - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved. -FAU - Orenes-Piñero, Esteban -AU - Orenes-Piñero E -AD - Department of Cardiology, Hospital Universitario Virgen de la Arrixaca, - Universidad de Murcia, Murcia, Spain. -FAU - Montoro-García, Silvia -AU - Montoro-García S -FAU - Patel, Jeetesh V -AU - Patel JV -FAU - Valdés, Mariano -AU - Valdés M -FAU - Marín, Francisco -AU - Marín F -FAU - Lip, Gregory Y H -AU - Lip GY -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121009 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (MicroRNAs) -SB - IM -CIN - Int J Cardiol. 2013 Oct 12;168(5):e135-7. doi: 10.1016/j.ijcard.2013.08.014. - PMID: 23978363 -CIN - Int J Cardiol. 2014 Feb 15;171(3):e84-5. doi: 10.1016/j.ijcard.2013.11.097. PMID: - 24377716 -MH - Animals -MH - Forecasting -MH - Humans -MH - MicroRNAs/*physiology -MH - Ventricular Remodeling/*physiology -OTO - NOTNLM -OT - Cardiac remodelling -OT - Fibrosis -OT - Ion channels -OT - Myocyte hypertrophy -OT - Therapeutic targets -OT - miRNA -EDAT- 2012/10/16 06:00 -MHDA- 2014/04/23 06:00 -CRDT- 2012/10/16 06:00 -PHST- 2012/03/30 00:00 [received] -PHST- 2012/09/20 00:00 [revised] -PHST- 2012/09/22 00:00 [accepted] -PHST- 2012/10/16 06:00 [entrez] -PHST- 2012/10/16 06:00 [pubmed] -PHST- 2014/04/23 06:00 [medline] -AID - S0167-5273(12)01241-7 [pii] -AID - 10.1016/j.ijcard.2012.09.120 [doi] -PST - ppublish -SO - Int J Cardiol. 2013 Sep 1;167(5):1651-9. doi: 10.1016/j.ijcard.2012.09.120. Epub - 2012 Oct 9. - -PMID- 21608058 -OWN - NLM -STAT- MEDLINE -DCOM- 20120113 -LR - 20250529 -IS - 1099-1492 (Electronic) -IS - 0952-3480 (Print) -IS - 0952-3480 (Linking) -VI - 24 -IP - 8 -DP - 2011 Oct -TI - Could 13C MRI assist clinical decision-making for patients with heart disease? -PG - 973-9 -LID - 10.1002/nbm.1718 [doi] -AB - Even at this early stage of development, it is clear that the imaging of - hyperpolarized (13)C-enriched molecules and their metabolic products offers a new - approach to the study of the physiology and disease of the heart. The technology - is practical in humans and, for this reason, we consider whether a role in - clinical decision-making should motivate further development. The range of - interventions available to treat coronary and valvular heart disease is already - extensive, and new options are imminent. Yet the appropriate management of - patients with left ventricular dysfunction can be challenging because the - mechanism of reduced function may be unclear and the ability of the ventricle to - respond to therapy may be difficult to predict. Pyruvate is a promising early - target for development as a diagnostic agent because it lies at a critical branch - point in cardiac biochemistry. The rate of metabolism of hyperpolarized pyruvate - to CO(2) relative to lactate may prove to be a useful indicator of preserved - mitochondrial function, and therefore provide a specific signal of viable - myocardium. Other species including physiological substrates and nonphysiological - molecules may provide additional information. Once suitable technology becomes - available, it is likely that clinical research will progress quickly. The ability - to monitor directly specific metabolic pathways may lead to an improvement in the - selection of patients who will benefit from interventions, pharmacologic or - otherwise. -CI - Copyright © 2011 John Wiley & Sons, Ltd. -FAU - Malloy, Craig R -AU - Malloy CR -AD - Advanced Imaging Research Center, University of Texas Southwestern Medical - Center, Dallas, TX 75390-8568, USA. craig.malloy@utsouthwestern.edu -FAU - Merritt, Matthew E -AU - Merritt ME -FAU - Sherry, A Dean -AU - Sherry AD -LA - eng -GR - P41 RR002584/RR/NCRR NIH HHS/United States -GR - R37 HL034557/HL/NHLBI NIH HHS/United States -GR - RR‐02584/RR/NCRR NIH HHS/United States -GR - HL‐034557/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20110524 -PL - England -TA - NMR Biomed -JT - NMR in biomedicine -JID - 8915233 -RN - 0 (Carbon Isotopes) -SB - IM -MH - *Carbon Isotopes -MH - Decision Making -MH - Heart Diseases/*metabolism/therapy -MH - Heart Ventricles/metabolism -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Myocardium/metabolism -PMC - PMC3174329 -MID - NIHMS295490 -EDAT- 2011/05/25 06:00 -MHDA- 2012/01/14 06:00 -PMCR- 2012/10/01 -CRDT- 2011/05/25 06:00 -PHST- 2010/11/03 00:00 [received] -PHST- 2011/01/25 00:00 [revised] -PHST- 2011/02/22 00:00 [accepted] -PHST- 2011/05/25 06:00 [entrez] -PHST- 2011/05/25 06:00 [pubmed] -PHST- 2012/01/14 06:00 [medline] -PHST- 2012/10/01 00:00 [pmc-release] -AID - 10.1002/nbm.1718 [doi] -PST - ppublish -SO - NMR Biomed. 2011 Oct;24(8):973-9. doi: 10.1002/nbm.1718. Epub 2011 May 24. - -PMID- 18300519 -OWN - NLM -STAT- MEDLINE -DCOM- 20080417 -LR - 20080227 -IS - 0025-682X (Print) -IS - 0025-682X (Linking) -VI - 67 -IP - 6 -DP - 2007 Dec -TI - [Heart failure due to non-infectious causes in developing countries: etiologic - approach and therapeutic principles]. -PG - 579-86 -AB - Cardiovascular disease is a major worldwide health problem with a growing impact - in developing countries. Heart failure is the clinical manifestation of many - advanced cardiac disorders. It can have numerous etiologies and the incidence of - non-infectious causes is increasing with socio-economic development, thus - illustrating the global nature of this epidemiologic transition. Several of the - numerous non-infectious causes of heart failure involve cardiac diseases specific - to tropical areas including dilated cardiomyopathy, endomyocardial fibrosis, and - peripartum cardiomyopathy. Other widespread disorders are becoming more common as - a result of the epidemiologic transition. Cardiovascular risk factors are - changing particularly with regard to the incidence of coronary artery disease, - ischemic cardiomyopathy, and hypertension-related complications. The purpose of - this article is to provide an overview of non-infectious causes of heart failure - in terms of frequency, onset, and therapeutic requirements. Symptomatic treatment - of heart failure is same as in developing countries but is often delayed due to - shortcomings in the care system. -FAU - Paule, P -AU - Paule P -AD - Service de Cardiologie, Hôpital d'Instruction des Armées Laveran, Marseille, - France. philippe.paule@orange.fr -FAU - Braem, L -AU - Braem L -FAU - Mioulet, D -AU - Mioulet D -FAU - Gil, J M -AU - Gil JM -FAU - Theron, A -AU - Theron A -FAU - Héno, P -AU - Héno P -FAU - Fourcade, L -AU - Fourcade L -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Insuffisance cardiaque d'origine non infectieuse en zone tropicale: approche - étiologique et principes thérapeutiques. -PL - France -TA - Med Trop (Mars) -JT - Medecine tropicale : revue du Corps de sante colonial -JID - 8710146 -SB - IM -MH - Alcohol Drinking/adverse effects/epidemiology -MH - Anemia, Sickle Cell/complications/epidemiology -MH - Beriberi/complications/epidemiology -MH - Cardiomyopathies/complications/epidemiology -MH - *Developed Countries -MH - Endomyocardial Fibrosis/complications/epidemiology -MH - Female -MH - Heart Failure/*etiology/*therapy -MH - Humans -MH - Puerperal Disorders/epidemiology -RF - 25 -EDAT- 2008/02/28 09:00 -MHDA- 2008/04/18 09:00 -CRDT- 2008/02/28 09:00 -PHST- 2008/02/28 09:00 [pubmed] -PHST- 2008/04/18 09:00 [medline] -PHST- 2008/02/28 09:00 [entrez] -PST - ppublish -SO - Med Trop (Mars). 2007 Dec;67(6):579-86. - -PMID- 23893053 -OWN - NLM -STAT- MEDLINE -DCOM- 20140527 -LR - 20180614 -IS - 1648-9144 (Electronic) -IS - 1010-660X (Linking) -VI - 49 -IP - 3 -DP - 2013 -TI - Ischemic heart disease: a comprehensive evaluation using cardiovascular magnetic - resonance. -PG - 97-110 -AB - Cardiovascular magnetic resonance is becoming an important imaging modality in - clinical cardiology. As an exceptionally accurate and comprehensive diagnostic - tool, cardiovascular magnetic resonance is becoming the first-choice modality for - imaging the heart and great vessels. Stress cardiovascular magnetic resonance - imaging enables the detection of hemodynamically significant coronary artery - lesions and the choice of treatment strategy when stenosis is intermediate. - Viability assessment is very important as it allows differentiating between - dysfunctional but still viable myocardium and predicts the recovery of - ventricular function after successful revascularization. However, the - availability and costs of cardiovascular magnetic resonance remain the major - obstacle and makes the investigation unachievable to many patients. -FAU - Lapinskas, Tomas -AU - Lapinskas T -AD - Department of Cardiology, Medical Academy, Lithuanian University of Health - Sciences, Kaunas, Lithuania. tomas.lapinskas@lsmuni.lt -LA - eng -PT - Journal Article -PT - Review -PL - Switzerland -TA - Medicina (Kaunas) -JT - Medicina (Kaunas, Lithuania) -JID - 9425208 -RN - 0 (Adrenergic beta-1 Receptor Agonists) -RN - 3S12J47372 (Dobutamine) -SB - IM -MH - Adrenergic beta-1 Receptor Agonists -MH - Costs and Cost Analysis -MH - Dobutamine -MH - Heart/diagnostic imaging/physiopathology -MH - Humans -MH - Magnetic Resonance Imaging/*economics/*methods -MH - Myocardial Ischemia/*diagnosis/diagnostic imaging/physiopathology -MH - Myocardial Perfusion Imaging -MH - Myocardium/pathology -MH - Ventricular Dysfunction, Left/diagnosis/physiopathology -EDAT- 2013/07/31 06:00 -MHDA- 2014/05/28 06:00 -CRDT- 2013/07/30 06:00 -PHST- 2013/07/30 06:00 [entrez] -PHST- 2013/07/31 06:00 [pubmed] -PHST- 2014/05/28 06:00 [medline] -AID - 1303-01e [pii] -PST - ppublish -SO - Medicina (Kaunas). 2013;49(3):97-110. - -PMID- 23683603 -OWN - NLM -STAT- MEDLINE -DCOM- 20131022 -LR - 20191112 -IS - 1482-1826 (Electronic) -IS - 1482-1826 (Linking) -VI - 16 -IP - 1 -DP - 2013 -TI - Efficacy and safety of platelet inhibitors. -PG - 1-39 -AB - Ischemic heart disease is the second leading cause of death in the world. The - proportion of deaths resulting from this condition has decreased in the last two - decades, mainly as a result of improved primary and secondary prevention of - cardiovascular events, as well as the development of patient awareness and - medical and pharmacological management. The purpose of the present review is to - analyze pathophysiological events leading to platelet involvement in - cardiovascular thrombosis, as well as the role of pharmacogenetics in modulating - the risk of cardiovascular disorders. The present work was performed using a - PubMed search with combinations of key words relevant to the subject in both - English and French. In addition to the pharmacokinetic and pharmacodynamic - characteristics of platelet inhibitors, this work reviews the efficacy and - adverse events observed during the clinical trials with these drugs. This review - further summarizes possible therapeutic drug monitoring strategies for - antiplatelet drugs. The novelty of this work is the description of the lymphocyte - toxicity assay as a specific method of diagnosing and predicting possible - idiosyncratic adverse events attributable to antiplatelet medication. -FAU - Binazon, Ornella -AU - Binazon O -AD - In Vitro Drug Safety and Biotechnology, Toronto, ON, Canada. -FAU - Dubois-Gauche, Audrey -AU - Dubois-Gauche A -FAU - Nanau, Radu M -AU - Nanau RM -FAU - Neuman, Manuela G -AU - Neuman MG -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Switzerland -TA - J Pharm Pharm Sci -JT - Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian - Society for Pharmaceutical Sciences, Societe canadienne des sciences - pharmaceutiques -JID - 9807281 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Acute Coronary Syndrome/drug therapy -MH - Drug Hypersensitivity -MH - Drug Interactions -MH - Humans -MH - Platelet Aggregation Inhibitors/pharmacology/*therapeutic use -MH - Treatment Outcome -EDAT- 2013/05/21 06:00 -MHDA- 2013/10/23 06:00 -CRDT- 2013/05/21 06:00 -PHST- 2013/05/21 06:00 [entrez] -PHST- 2013/05/21 06:00 [pubmed] -PHST- 2013/10/23 06:00 [medline] -AID - 10.18433/j3mp4z [doi] -PST - ppublish -SO - J Pharm Pharm Sci. 2013;16(1):1-39. doi: 10.18433/j3mp4z. - -PMID- 21457328 -OWN - NLM -STAT- MEDLINE -DCOM- 20110816 -LR - 20110404 -IS - 1399-0012 (Electronic) -IS - 0902-0063 (Linking) -VI - 25 -IP - 2 -DP - 2011 Mar-Apr -TI - Cardiac allograft vasculopathy: current knowledge and future direction. -PG - 175-84 -LID - 10.1111/j.1399-0012.2010.01307.x [doi] -AB - Cardiac allograft vasculopathy (CAV) is a unique form of coronary artery disease - affecting heart transplant recipients. Although prognosis of heart transplant - recipients has improved over time, CAV remains a significant cause of mortality - beyond the first year of cardiac transplantation. Many traditional and - non-traditional risk factors for the development of CAV have been described. - Traditional risk factors include dyslipidemia, diabetes and hypertension. - Non-traditional risk factors include cytomegalovirus infection, HLA mismatch, - antibody-mediated rejection, and mode of donor brain death. There is a complex - interplay between immunological and non-immunological factors ultimately leading - to endothelial injury and exaggerated repair response. Pathologically, CAV - manifests as fibroelastic proliferation of intima and luminal stenosis. Early - diagnosis is paramount as heart transplant recipients are frequently asymptomatic - owing to cardiac denervation related to the transplant surgery. Intravascular - ultrasound (IVUS) offers many advantages over conventional angiography and is an - excellent predictor of prognosis in heart transplant recipients. Many - non-invasive diagnostic tests including dobutamine stress echocardiography, CT - angiography, and MRI are available; though, none has replaced angiography. This - review discusses the risk factors, pathogenesis, and diagnosis of CAV and - highlights some current concepts and recent developments in this field. -CI - © 2011 John Wiley & Sons A/S. -FAU - Colvin-Adams, Monica -AU - Colvin-Adams M -AD - University of Minnesota, Minneapolis, MN, USA. colvi005@umn.edu -FAU - Agnihotri, Adheesh -AU - Agnihotri A -LA - eng -PT - Journal Article -PT - Review -PL - Denmark -TA - Clin Transplant -JT - Clinical transplantation -JID - 8710240 -SB - IM -MH - Heart Transplantation/*adverse effects -MH - Humans -MH - Transplantation, Homologous -MH - Vascular Diseases/*diagnosis/*etiology -EDAT- 2011/04/05 06:00 -MHDA- 2011/08/17 06:00 -CRDT- 2011/04/05 06:00 -PHST- 2011/04/05 06:00 [entrez] -PHST- 2011/04/05 06:00 [pubmed] -PHST- 2011/08/17 06:00 [medline] -AID - 10.1111/j.1399-0012.2010.01307.x [doi] -PST - ppublish -SO - Clin Transplant. 2011 Mar-Apr;25(2):175-84. doi: - 10.1111/j.1399-0012.2010.01307.x. - -PMID- 20122544 -OWN - NLM -STAT- MEDLINE -DCOM- 20100826 -LR - 20100203 -IS - 0914-5087 (Print) -IS - 0914-5087 (Linking) -VI - 55 -IP - 1 -DP - 2010 Jan -TI - Clinical characteristics and outcomes of heart failure with preserved ejection - fraction: lessons from epidemiological studies. -PG - 13-22 -LID - 10.1016/j.jjcc.2009.09.003 [doi] -AB - Recent epidemiological studies have demonstrated that nearly half of all patients - with heart failure (HF) have preserved left ventricular ejection fraction - (HFPEF). Compared to those with reduced EF, patients with HFPEF are older, more - likely to be women, less likely to have coronary artery disease, and more likely - to have hypertension and atrial fibrillation. Patients with HFPEF receive - different pharmacological as well as nonpharmacological treatments from those - with reduced EF. Morbidity and mortality in patients with HFPEF are largely - similar to those with reduced EF. Although much information has recently been - obtained about the clinical characteristics, medications, and outcomes of HFPEF - by large-scale clinical and epidemiological studies, effective management - strategies need to be established for this type of HF. -CI - 2009 Japanese College of Cardiology. Published by Elsevier Ltd. All rights - reserved. -FAU - Tsutsui, Hiroyuki -AU - Tsutsui H -AD - Department of Cardiovascular Medicine, Hokkaido University Graduate School of - Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo 060-8638, Japan. - htsutsui@med.hokudai.ac.jp -FAU - Tsuchihashi-Makaya, Miyuki -AU - Tsuchihashi-Makaya M -FAU - Kinugawa, Shintaro -AU - Kinugawa S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20091107 -PL - Netherlands -TA - J Cardiol -JT - Journal of cardiology -JID - 8804703 -SB - IM -MH - Aged -MH - Epidemiologic Studies -MH - Female -MH - Heart Failure/drug therapy/*physiopathology -MH - Humans -MH - Male -MH - Stroke Volume/*physiology -MH - Ventricular Function, Left/physiology -RF - 42 -EDAT- 2010/02/04 06:00 -MHDA- 2010/08/27 06:00 -CRDT- 2010/02/04 06:00 -PHST- 2009/09/29 00:00 [received] -PHST- 2009/09/30 00:00 [accepted] -PHST- 2010/02/04 06:00 [entrez] -PHST- 2010/02/04 06:00 [pubmed] -PHST- 2010/08/27 06:00 [medline] -AID - S0914-5087(09)00275-5 [pii] -AID - 10.1016/j.jjcc.2009.09.003 [doi] -PST - ppublish -SO - J Cardiol. 2010 Jan;55(1):13-22. doi: 10.1016/j.jjcc.2009.09.003. Epub 2009 Nov - 7. - -PMID- 17288956 -OWN - NLM -STAT- MEDLINE -DCOM- 20070322 -LR - 20161124 -IS - 1579-2242 (Electronic) -IS - 0300-8932 (Linking) -VI - 60 -IP - 1 -DP - 2007 Jan -TI - [Acute right atrial and ventricular infarction]. -PG - 51-66 -AB - Acute coronary syndromes involving the right side of the heart are associated - with increased mortality, a complex clinical course, and lengthy hospitalization, - as well as with frequent mechanical and electrical complications. It is important - that the signs and symptoms associated with the spread of ischemic disease to the - right heart chambers are recognized so that the patient can be given appropriate - treatment, which can improve short-term and long-term prognosis. The purpose of - this review was to summarize key aspects of the diagnosis, prognosis and - treatment of this condition. -FAU - Vargas-Barrón, Jesús -AU - Vargas-Barrón J -AD - Departamento de Ecocardiografía, Instituto Nacional de Cardiología Ignacio - Chávez, México. eco_vargas@terra.com.mx -FAU - Romero-Cárdenas, Angel -AU - Romero-Cárdenas A -FAU - Roldán, Francisco J -AU - Roldán FJ -FAU - Vázquez-Antona, Clara A -AU - Vázquez-Antona CA -LA - spa -PT - Journal Article -PT - Review -TT - Infarto agudo de aurícula y ventrículo derechos. -PL - Spain -TA - Rev Esp Cardiol -JT - Revista espanola de cardiologia -JID - 0404277 -SB - IM -MH - Echocardiography -MH - Electrocardiography -MH - Heart Atria/diagnostic imaging -MH - Heart Ventricles/diagnostic imaging -MH - Humans -MH - Magnetic Resonance Imaging -MH - Myocardial Infarction/*diagnosis/pathology/physiopathology/therapy -MH - Prognosis -MH - Tomography, Emission-Computed, Single-Photon -MH - Ventricular Dysfunction, Right/etiology/physiopathology -RF - 102 -EDAT- 2007/02/10 09:00 -MHDA- 2007/03/23 09:00 -CRDT- 2007/02/10 09:00 -PHST- 2007/02/10 09:00 [pubmed] -PHST- 2007/03/23 09:00 [medline] -PHST- 2007/02/10 09:00 [entrez] -AID - 13097926 [pii] -PST - ppublish -SO - Rev Esp Cardiol. 2007 Jan;60(1):51-66. - -PMID- 21354678 -OWN - NLM -STAT- MEDLINE -DCOM- 20110719 -LR - 20131121 -IS - 1532-1681 (Electronic) -IS - 0268-960X (Linking) -VI - 25 -IP - 3 -DP - 2011 May -TI - Effectiveness and safety of combined antiplatelet and anticoagulant therapy: a - critical review of the evidence from randomized controlled trials. -PG - 123-9 -LID - 10.1016/j.blre.2011.01.007 [doi] -AB - Antiplatelet and anticoagulant drugs are effective for the prevention of arterial - and venous thrombosis but patients continue to experience major cardiovascular - events despite their use. Strategies to improve the effectiveness of - antithrombotic therapies include selecting the optimal drug and dosing regimen, - the use of combinations of antiplatelet and anticoagulant drugs and the - development of new more effective drugs to replace existing therapies. Evidence - from randomized controlled trials indicates that the combination of aspirin and - an anticoagulant is more effective than aspirin alone for the prevention of - recurrent cardiovascular events in patients with acute coronary syndrome and is - more effective than anticoagulation alone for the prevention of thromboembolic - events in patients with mechanical heart valves, but at a cost of increased - bleeding. Randomized controlled trials provide no evidence for improved - effectiveness of combination therapy compared with antiplatelet therapy alone for - the prevention of recurrent cardiovascular events in patients with - non-cardioembolic stroke or peripheral artery disease, or compared with - anticoagulant therapy alone for the prevention of stroke in patients with atrial - fibrillation. Despite lack of evaluation in randomized controlled trials, - combination therapy is commonly used in patients with separate indications for - antiplatelet therapy (e.g., acute coronary syndrome, recent coronary artery - stent) and anticoagulant therapy (e.g., atrial fibrillation with at least one - additional risk factor for stroke). Randomized trials are urgently required to - evaluate the effectiveness and safety of combining antiplatelet and anticoagulant - therapy in these settings. -CI - Copyright © 2011 Elsevier Ltd. All rights reserved. -FAU - Paikin, Jeremy S -AU - Paikin JS -AD - Cardiology Fellow, Hamilton General Hospital, McMaster University, Hamilton, - Ontario, Canada. paikinjs@mcmaster.ca -FAU - Wright, Doug S -AU - Wright DS -FAU - Eikelboom, John W -AU - Eikelboom JW -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -DEP - 20110226 -PL - England -TA - Blood Rev -JT - Blood reviews -JID - 8708558 -RN - 0 (Anticoagulants) -RN - 0 (Platelet Aggregation Inhibitors) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Anticoagulants/adverse effects/*therapeutic use -MH - Aspirin/therapeutic use -MH - Drug Therapy, Combination -MH - Humans -MH - Platelet Aggregation Inhibitors/adverse effects/*therapeutic use -MH - Randomized Controlled Trials as Topic -EDAT- 2011/03/01 06:00 -MHDA- 2011/07/20 06:00 -CRDT- 2011/03/01 06:00 -PHST- 2011/03/01 06:00 [entrez] -PHST- 2011/03/01 06:00 [pubmed] -PHST- 2011/07/20 06:00 [medline] -AID - S0268-960X(11)00008-7 [pii] -AID - 10.1016/j.blre.2011.01.007 [doi] -PST - ppublish -SO - Blood Rev. 2011 May;25(3):123-9. doi: 10.1016/j.blre.2011.01.007. Epub 2011 Feb - 26. - -PMID- 18535269 -OWN - NLM -STAT- MEDLINE -DCOM- 20080612 -LR - 20250529 -IS - 1524-4571 (Electronic) -IS - 0009-7330 (Print) -IS - 0009-7330 (Linking) -VI - 102 -IP - 11 -DP - 2008 Jun 6 -TI - Aging and disease as modifiers of efficacy of cell therapy. -PG - 1319-30 -LID - 10.1161/CIRCRESAHA.108.175943 [doi] -AB - Cell therapy is a promising option for treating ischemic diseases and heart - failure. Adult stem and progenitor cells from various sources have experimentally - been shown to augment the functional recovery after ischemia, and clinical trials - have confirmed that autologous cell therapy using bone marrow-derived or - circulating blood-derived progenitor cells is safe and provides beneficial - effects. However, aging and risk factors for coronary artery disease affect the - functional activity of the endogenous stem/progenitor cell pools, thereby at - least partially limiting the therapeutic potential of the applied cells. In - addition, age and disease affect the tissue environment, in which the cells are - infused or injected. The present review article will summarize current evidence - for cell impairment during aging and disease but also discuss novel approaches - how to reverse the dysfunction of cells or to refresh the target tissue. - Pretreatment of cells or the target tissue by small molecules, polymers, growth - factors, or a combination thereof may provide useful approaches for enhancement - of cell therapy for cardiovascular diseases. -FAU - Dimmeler, Stefanie -AU - Dimmeler S -AD - Molecular Cardiology, Department of Internal Medicine III, University of - Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany. - Dimmeler@em.uni-frankfurt.de -FAU - Leri, Annarosa -AU - Leri A -LA - eng -GR - P01 AG023071/AG/NIA NIH HHS/United States -GR - R01 AG026107/AG/NIA NIH HHS/United States -GR - R01 HL065577/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Circ Res -JT - Circulation research -JID - 0047103 -RN - 0 (Intercellular Signaling Peptides and Proteins) -SB - IM -MH - Adult Stem Cells/drug effects/transplantation -MH - *Aging -MH - Animals -MH - Cellular Senescence/drug effects -MH - Heart Diseases/physiopathology/*therapy -MH - Humans -MH - Intercellular Signaling Peptides and Proteins/pharmacology -MH - Risk Factors -MH - *Stem Cell Transplantation/methods -MH - Treatment Outcome -PMC - PMC2728476 -MID - NIHMS127136 -EDAT- 2008/06/07 09:00 -MHDA- 2008/06/13 09:00 -PMCR- 2009/08/18 -CRDT- 2008/06/07 09:00 -PHST- 2008/06/07 09:00 [pubmed] -PHST- 2008/06/13 09:00 [medline] -PHST- 2008/06/07 09:00 [entrez] -PHST- 2009/08/18 00:00 [pmc-release] -AID - 102/11/1319 [pii] -AID - 10.1161/CIRCRESAHA.108.175943 [doi] -PST - ppublish -SO - Circ Res. 2008 Jun 6;102(11):1319-30. doi: 10.1161/CIRCRESAHA.108.175943. - -PMID- 24438730 -OWN - NLM -STAT- MEDLINE -DCOM- 20140311 -LR - 20220410 -IS - 1873-1740 (Electronic) -IS - 0033-0620 (Linking) -VI - 56 -IP - 4 -DP - 2014 Jan-Feb -TI - Impact of obesity and weight loss on cardiac performance and morphology in - adults. -PG - 391-400 -LID - S0033-0620(13)00156-4 [pii] -LID - 10.1016/j.pcad.2013.09.003 [doi] -AB - Obesity, particularly severe obesity is capable of producing hemodynamic - alterations that predispose to changes in cardiac morphology and ventricular - function. These include increased cardiac output, left ventricular hypertrophy - and diastolic and systolic dysfunction of both ventricles. Facilitated by - co-morbidities such as hypertension, the sleep apnea/obesity hypoventilation - syndrome, and possibly certain neurohormonal and metabolic alterations, these - abnormalities may predispose to left and right heart failure, a disorder known as - obesity cardiomyopathy. -CI - © 2013. -FAU - Alpert, Martin A -AU - Alpert MA -AD - Division of Cardiovascular Medicine, University of Missouri School of Medicine, - Columbia, MO 65202. Electronic address: alpertm@health.missouri.edu. -FAU - Omran, Jad -AU - Omran J -AD - Division of Cardiovascular Medicine, University of Missouri School of Medicine, - Columbia, MO 65202. -FAU - Mehra, Ankit -AU - Mehra A -AD - Division of Cardiovascular Medicine, University of Missouri School of Medicine, - Columbia, MO 65202. -FAU - Ardhanari, Sivakumar -AU - Ardhanari S -AD - Division of Cardiovascular Medicine, University of Missouri School of Medicine, - Columbia, MO 65202. -LA - eng -PT - Journal Article -PT - Review -DEP - 20131026 -PL - United States -TA - Prog Cardiovasc Dis -JT - Progress in cardiovascular diseases -JID - 0376442 -SB - IM -MH - Adult -MH - Body Mass Index -MH - *Cardiac Output -MH - Comorbidity -MH - Diet, Fat-Restricted -MH - Female -MH - Heart Failure/*epidemiology/physiopathology -MH - Heart Failure, Diastolic/epidemiology/physiopathology -MH - Heart Failure, Systolic/epidemiology/physiopathology -MH - Humans -MH - Male -MH - Middle Aged -MH - Obesity/*diet therapy/*epidemiology/physiopathology -MH - Obesity Hypoventilation Syndrome/epidemiology/physiopathology -MH - Obesity, Morbid/epidemiology/physiopathology -MH - Prognosis -MH - Survival Analysis -MH - Ventricular Dysfunction, Left/epidemiology/physiopathology -MH - Ventricular Dysfunction, Right/epidemiology/physiopathology -MH - *Weight Loss -OTO - NOTNLM -OT - BMI -OT - BP -OT - CAD -OT - CBV -OT - CO -OT - Diastolic dysfunction -OT - HF -OT - HTN -OT - High cardiac output -OT - LA -OT - LV -OT - Left ventricular hypertrophy -OT - Obesity -OT - PVR -OT - RAAS -OT - RV -OT - Systolic dysfunction -OT - TG -OT - blood pressure -OT - body mass index -OT - cardiac output -OT - central blood volume -OT - coronary artery disease -OT - heart failure -OT - left atrial or left atrium -OT - left ventricular or left ventricle -OT - peripheral vascular resistance -OT - renin–angiotensin–aldosterone system -OT - right ventricular or right ventricle -OT - systemic hypertension -OT - triglyceride(s) -EDAT- 2014/01/21 06:00 -MHDA- 2014/03/13 06:00 -CRDT- 2014/01/21 06:00 -PHST- 2014/01/21 06:00 [entrez] -PHST- 2014/01/21 06:00 [pubmed] -PHST- 2014/03/13 06:00 [medline] -AID - S0033-0620(13)00156-4 [pii] -AID - 10.1016/j.pcad.2013.09.003 [doi] -PST - ppublish -SO - Prog Cardiovasc Dis. 2014 Jan-Feb;56(4):391-400. doi: 10.1016/j.pcad.2013.09.003. - Epub 2013 Oct 26. - -PMID- 19505734 -OWN - NLM -STAT- MEDLINE -DCOM- 20100505 -LR - 20220409 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 139 -IP - 1 -DP - 2010 Feb 18 -TI - Obstructive sleep apnea and cardiovascular disease. -PG - 7-16 -LID - 10.1016/j.ijcard.2009.05.021 [doi] -AB - Obstructive sleep apnea (OSA) is a common yet an under-diagnosed sleep related - breathing disorder affecting predominantly middle-aged men. OSA is associated - with many adverse health outcomes, including cardiovascular disease. Common OSA - associated/induced cardiovascular disorders include coronary artery disease, - heart failure, hypertension, cardiac arrhythmias and stroke, which further - increase morbidity and mortality in the OSA population. Endothelial dysfunction, - coagulopathy, impaired sympathetic drive, oxidative and inflammatory stress are - the pathophysiological pathways suggested for the development of cardiovascular - disease in OSA. The evidence would suggest that OSA should be considered as a - cardiovascular risk factor, and is a treatable condition. Multiple studies using - Continuous Positive Airway Pressure (CPAP) have shown improvements in the - clinical state as well as retardation of disease progression. Therefore, patients - with cardiovascular disease should be proactively screened for OSA and vice - versa. -CI - Copyright 2009 Elsevier Ireland Ltd. All rights reserved. -FAU - Butt, Mehmood -AU - Butt M -AD - University Department of Medicine, City Hospital, Birmingham B18 7QH, UK. -FAU - Dwivedi, Girish -AU - Dwivedi G -FAU - Khair, Omer -AU - Khair O -FAU - Lip, Gregory Y H -AU - Lip GY -LA - eng -PT - Journal Article -PT - Review -DEP - 20090607 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -SB - IM -MH - *Cardiovascular Diseases/metabolism/mortality/physiopathology -MH - Humans -MH - Morbidity -MH - Risk Factors -MH - *Sleep Apnea, Obstructive/metabolism/mortality/physiopathology -RF - 182 -EDAT- 2009/06/10 09:00 -MHDA- 2010/05/06 06:00 -CRDT- 2009/06/10 09:00 -PHST- 2009/03/14 00:00 [received] -PHST- 2009/05/07 00:00 [revised] -PHST- 2009/05/11 00:00 [accepted] -PHST- 2009/06/10 09:00 [entrez] -PHST- 2009/06/10 09:00 [pubmed] -PHST- 2010/05/06 06:00 [medline] -AID - S0167-5273(09)00563-4 [pii] -AID - 10.1016/j.ijcard.2009.05.021 [doi] -PST - ppublish -SO - Int J Cardiol. 2010 Feb 18;139(1):7-16. doi: 10.1016/j.ijcard.2009.05.021. Epub - 2009 Jun 7. - -PMID- 16829789 -OWN - NLM -STAT- MEDLINE -DCOM- 20060823 -LR - 20061025 -IS - 0041-1337 (Print) -IS - 0041-1337 (Linking) -VI - 82 -IP - 1 Suppl -DP - 2006 Jul 15 -TI - Angiogenic growth factors in cardiac allograft rejection. -PG - S22-4 -AB - Normal adult vasculature is in a quiescent state. In transplanted hearts, peri- - and postoperative ischemic and alloimmune stimuli may be interpreted as - inadequate tissue perfusion leading to activation of angiogenic signaling. - Although this may have protective functions, improper activation of cardiac - allograft endothelial cells and smooth muscle cells may actually result in - impaired survival of cardiac allografts. In this paper, we review the current - knowledge on angiogenic growth factors, vascular endothelial growth factor, - angiopoietins, and platelet-derived growth factor in cardiac allografts. We also - discuss the potential for therapies aimed at angiogenic growth factors in - preventing and treating cardiac allograft rejection and transplant coronary - artery disease. -FAU - Nykänen, Antti I -AU - Nykänen AI -AD - Cardiopulmonary Research Group, Transplantation Laboratory, University of - Helsinki, and Helsinki University Central Hospital, Helsinki, Finland. -FAU - Tikkanen, Jussi M -AU - Tikkanen JM -FAU - Krebs, Rainer -AU - Krebs R -FAU - Keränen, Mikko A I -AU - Keränen MA -FAU - Sihvola, Roope K -AU - Sihvola RK -FAU - Sandelin, Henrik -AU - Sandelin H -FAU - Tuuminen, Raimo -AU - Tuuminen R -FAU - Raisky, Olivier -AU - Raisky O -FAU - Koskinen, Petri K -AU - Koskinen PK -FAU - Lemström, Karl B -AU - Lemström KB -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Transplantation -JT - Transplantation -JID - 0132144 -RN - 0 (Angiogenic Proteins) -SB - IM -EIN - Transplantation. 2006 Sep 15;82(5):721 -MH - Angiogenic Proteins/*physiology -MH - *Graft Rejection/prevention & control/therapy -MH - *Heart Transplantation/immunology -MH - Humans -MH - *Neovascularization, Physiologic -RF - 28 -EDAT- 2006/07/11 09:00 -MHDA- 2006/08/24 09:00 -CRDT- 2006/07/11 09:00 -PHST- 2006/07/11 09:00 [pubmed] -PHST- 2006/08/24 09:00 [medline] -PHST- 2006/07/11 09:00 [entrez] -AID - 00007890-200607151-00008 [pii] -AID - 10.1097/01.tp.0000231443.12570.57 [doi] -PST - ppublish -SO - Transplantation. 2006 Jul 15;82(1 Suppl):S22-4. doi: - 10.1097/01.tp.0000231443.12570.57. - -PMID- 22961192 -OWN - NLM -STAT- MEDLINE -DCOM- 20130430 -LR - 20211021 -IS - 1546-9549 (Electronic) -IS - 1546-9530 (Linking) -VI - 9 -IP - 4 -DP - 2012 Dec -TI - Growth differentiation factor 15 in heart failure: an update. -PG - 337-45 -LID - 10.1007/s11897-012-0113-9 [doi] -AB - Growth differentiation factor 15 (GDF-15) is a stress-responsive cytokine - expressed in the cardiovascular system. GDF-15 is emerging as a biomarker of - cardiometabolic risk and disease burden. GDF-15 integrates information from - cardiac and extracardiac disease pathways that are linked to the incidence, - progression, and prognosis of heart failure (HF). Increased circulating levels of - GDF-15 are associated with an increased risk of developing HF in apparently - healthy individuals from the community. After an acute coronary syndrome, - elevated levels of GDF-15 are indicative of an increased risk of developing - adverse left ventricular remodeling and HF. In patients with established HF, the - levels of GDF-15 and increases in GDF-15 over time are associated with adverse - outcomes. The information provided by GDF-15 is independent of established risk - factors and cardiac biomarkers, including BNP. More studies are needed to - elucidate how the information provided by GDF-15 can be used for patient - monitoring and formulating treatment decisions. Further understanding of the - pathobiology of GDF-15 may lead to the discovery of new treatment targets in HF. -FAU - Wollert, Kai C -AU - Wollert KC -AD - Division of Molecular and Translational Cardiology, Department of Cardiology and - Angiology, Hannover Medical School, Hannover, Germany. wollert.kai@mh-hannover.de -FAU - Kempf, Tibor -AU - Kempf T -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Heart Fail Rep -JT - Current heart failure reports -JID - 101196487 -RN - 0 (Biomarkers) -RN - 0 (GDF15 protein, human) -RN - 0 (Growth Differentiation Factor 15) -SB - IM -MH - Biomarkers/metabolism -MH - Cardiovascular Diseases/metabolism -MH - Growth Differentiation Factor 15/metabolism/*physiology -MH - Heart Failure/diagnosis/*physiopathology/therapy -MH - Humans -MH - Prognosis -EDAT- 2012/09/11 06:00 -MHDA- 2013/05/01 06:00 -CRDT- 2012/09/11 06:00 -PHST- 2012/09/11 06:00 [entrez] -PHST- 2012/09/11 06:00 [pubmed] -PHST- 2013/05/01 06:00 [medline] -AID - 10.1007/s11897-012-0113-9 [doi] -PST - ppublish -SO - Curr Heart Fail Rep. 2012 Dec;9(4):337-45. doi: 10.1007/s11897-012-0113-9. - -PMID- 16938589 -OWN - NLM -STAT- MEDLINE -DCOM- 20070612 -LR - 20151119 -IS - 0272-2712 (Print) -IS - 0272-2712 (Linking) -VI - 26 -IP - 3 -DP - 2006 Sep -TI - Measures of thrombosis and fibrinolysis. -PG - 655-78, vii -AB - Our recent understanding of acute coronary syndrome as an atherothrombotic - process has led to research efforts in the development of markers of thrombosis - and fibrinolysis for risk prediction in cardiovascular heart disease. Although - American Heart Association/American College of Cardiology guidelines recommend - fibrinogen as a category I risk factor and also suggest factor VII, plasminogen - activator inhibitor-1, tissue-type plasminogen activator, and von Willebrand - factor as other potentially clinically useful markers, these tests have not come - into routine clinical use. Their development as predictors of risk may be - hampered by inconsistent laboratory methodology, which causes difficulty in - comparing result interpretation with published trial studies. This article - presents the history of development for these tests, proper laboratory handling, - the best trial data that present evidence of their accuracy, and current - guidelines for clinical use. -FAU - Choi, Brian G -AU - Choi BG -AD - Cardiovascular Biology Research Laboratory, Zena and Michael A. Wiener - Cardiovascular Institute, Mount Sinai School of Medicine, One Gustave L. Levy - Place, Box 1030, New York, NY 10029, USA. -FAU - Vilahur, Gemma -AU - Vilahur G -FAU - Ibanez, Borja -AU - Ibanez B -FAU - Zafar, M Urooj -AU - Zafar MU -FAU - Rodriguez, Jose -AU - Rodriguez J -FAU - Badimon, Juan J -AU - Badimon JJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Lab Med -JT - Clinics in laboratory medicine -JID - 8100174 -RN - 0 (Biomarkers) -SB - IM -MH - Biomarkers -MH - Fibrinolysis/*physiology -MH - Humans -MH - Reference Standards -MH - Specimen Handling -MH - Thrombosis/*diagnosis/*physiopathology -RF - 93 -EDAT- 2006/08/30 09:00 -MHDA- 2007/06/15 09:00 -CRDT- 2006/08/30 09:00 -PHST- 2006/08/30 09:00 [pubmed] -PHST- 2007/06/15 09:00 [medline] -PHST- 2006/08/30 09:00 [entrez] -AID - S0272-2712(06)00047-3 [pii] -AID - 10.1016/j.cll.2006.06.002 [doi] -PST - ppublish -SO - Clin Lab Med. 2006 Sep;26(3):655-78, vii. doi: 10.1016/j.cll.2006.06.002. - -PMID- 23529608 -OWN - NLM -STAT- MEDLINE -DCOM- 20140213 -LR - 20250703 -IS - 2047-4881 (Electronic) -IS - 2047-4873 (Linking) -VI - 20 -IP - 4 -DP - 2013 Aug -TI - Dose-comparative effects of different statins on serum lipid levels: a network - meta-analysis of 256,827 individuals in 181 randomized controlled trials. -PG - 658-70 -LID - 10.1177/2047487313483600 [doi] -AB - AIMS: The extent to which individual statins vary in terms of their impact on - serum lipid levels has been studied mainly on the basis of placebo-controlled - trials. Our objective was to review and quantify the dose-comparative effects of - different statins on serum lipid levels using both placebo- and active-comparator - trials. METHODS: We systematically reviewed randomized trials evaluating - different statins in participants with, or at risk of developing, cardiovascular - disease. We performed random-effects Bayesian network meta-analyses to quantify - the the relative potency of individual statins across all possible dose - combinations using both direct and indirect evidence. Dose-comparative effects - were determined by estimating the mean change from baseline in serum lipids as - compared to control treatment. (systematic review registration: PROSPERO - 2011:CRD42011001470). RESULTS: We included 181 placebo-controlled and - active-comparator trials including 256,827 individuals. There were 83 two-armed - placebo-controlled trials and the remaining 98 were two- or multi-armed - active-comparator trials. All statins reduced serum LDL and total cholesterol - levels: higher doses resulted in higher reductions in pretreatment LDL and total - cholesterol concentrations. In absolute terms, all statins significantly reduced - LDL cholesterol levels as compared to control treatment from average baseline - levels of approximately 150 mg/dl, except for fluvastatin at ≤20 mg/day and - lovastatin at ≤10 mg/day. Atorvastatin, rosuvastatin, and simvastatin were - broadly equivalent in terms of their LDL cholesterol-lowering effects. - Dose-comparative effects of indivudual statins were not different between those - with and without coronary heart disease at baseline. According to meta-regression - analyses, LDL cholesterol-lowering effects of individual statins were not - impacted by differences across trials in terms of baseline mean age and - proportion of women as trial participants. Pretreatment LDL cholesterol - concentrations had a marginally statistically significant effect on LDL - cholesterol change from baseline. Mean differences from baseline in HDL - cholesterol as compared to control treatment was not significant for any - statin-dose combination. CONCLUSIONS: The findings of this comprehensive review - provide supporting evidence for the dose-response relationship of statins in - reducing LDL and total cholesterol. The LDL cholesterol-reducing effects of some - statins appear less pronounced than the findings of previous meta-analyses, which - is particularly the case for the high-dose formulations of atorvastatin and - rosuvastatin. The most consistent evidence for a combined reduction in both LDL - and total cholesterol was achieved with atorvastatin at >40 mg/day, rosuvastatin - at >10 mg/day, and simvastatin at >40 mg/day, which appear equivalent in terms of - their LDL and total cholesterol-reducing effects. -FAU - Naci, Huseyin -AU - Naci H -AD - Department of Social Policy, London School of Economics & Political Science, - London, UK. h.naci@lse.ac.uk -FAU - Brugts, Jasper J -AU - Brugts JJ -FAU - Fleurence, Rachael -AU - Fleurence R -FAU - Ades, A E -AU - Ades AE -LA - eng -GR - MC_U145079307/MRC_/Medical Research Council/United Kingdom -PT - Journal Article -PT - Network Meta-Analysis -PT - Review -PT - Systematic Review -DEP - 20130325 -PL - England -TA - Eur J Prev Cardiol -JT - European journal of preventive cardiology -JID - 101564430 -RN - 0 (Biomarkers) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Lipids) -SB - IM -MH - Bayes Theorem -MH - Biomarkers/blood -MH - Cardiovascular Diseases/blood/diagnosis/etiology/*prevention & control -MH - Dose-Response Relationship, Drug -MH - Dyslipidemias/blood/complications/diagnosis/*drug therapy -MH - Evidence-Based Medicine -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage -MH - Lipids/*blood -MH - Markov Chains -MH - Monte Carlo Method -MH - *Randomized Controlled Trials as Topic -MH - Risk Factors -MH - Treatment Outcome -OTO - NOTNLM -OT - Statins -OT - cholesterol -OT - indirect comparison -OT - meta-analysis -OT - mixed treatment comparison -OT - systematic review -EDAT- 2013/03/27 06:00 -MHDA- 2014/02/14 06:00 -CRDT- 2013/03/27 06:00 -PHST- 2013/03/27 06:00 [entrez] -PHST- 2013/03/27 06:00 [pubmed] -PHST- 2014/02/14 06:00 [medline] -AID - 2047487313483600 [pii] -AID - 10.1177/2047487313483600 [doi] -PST - ppublish -SO - Eur J Prev Cardiol. 2013 Aug;20(4):658-70. doi: 10.1177/2047487313483600. Epub - 2013 Mar 25. - -PMID- 23461430 -OWN - NLM -STAT- MEDLINE -DCOM- 20130821 -LR - 20230823 -IS - 1944-706X (Electronic) -IS - 1083-4087 (Print) -IS - 1083-4087 (Linking) -VI - 19 -IP - 2 -DP - 2013 Mar -TI - Management of familial hypercholesterolemia: a review of the recommendations from - the National Lipid Association Expert Panel on Familial Hypercholesterolemia. -PG - 139-49 -LID - 10.18553/jmcp.2013.19.2.139 -AB - Familial hypercholesterolemia (FH) is a genetic disorder of lipid metabolism that - is characterized by a significant elevation in levels of low-density lipoprotein - cholesterol (LDL-C), and patients are at very high risk for premature coronary - heart disease (CHD). The etiology of FH includes known mutations in the gene of - the LDL receptor, LDLR; the gene of apolipoprotein B, apo B; and the proprotein - convertase subtilisin/kexin type 9 gene, PCSK9. The National Lipid Association - Expert Panel on Familial Hypercholesterolemia has provided recommendations for - the screening and treatment of patients with FH. Early identification and - aggressive treatment of FH in individual patients, as well as screening of all - first-degree relatives, are recommended to minimize the risk for premature CHD. - Similar to patients with conventional hypercholesterolemia, patients with FH - should receive statins as initial treatment, but patients with FH may require - higher doses of statins, more potent statins, statin-based combination therapy, - or adjunctive therapies. Patients with FH who have additional risk factors for, - or existing, cardiovascular disease or those with an inadequate response to - initial statin therapy should have access to higher doses of the most efficacious - statins; statins used in combination with other LDL-C-lowering agents should also - be supported by formularies; additional treatments, such as LDL-C apheresis or - novel therapies, may also be required to achieve acceptable LDL-C levels. New - treatment approaches include mipomersen, which was approved by the FDA in January - 2013. Mipomersen is an oligonucleotide inhibitor of apolipoprotein B-100 - synthesis (called an antisense inhibitor) indicated as an adjunct to - lipid-lowering medications and diet to reduce LDL-C, apolipoprotein B, total - cholesterol, and non-high density lipoprotein-cholesterol (non-HDL-C) levels in - patients with homozygous FH (HoFH). The microsomal transfer protein lomitapide - has also received FDA approval for use only in patients with HoFH. Other novel - treatments currently in development include PCSK9 inhibitors. Therapies such as - apheresis are likely more expensive than simple therapy with a statin but may be - needed to achieve long-term reductions in complications from nonfatal and fatal - cardiovascular events and hospitalizations related to myocardial infarction, - cardiac revascularization, and stroke in FH patients. The cost-effectiveness of - this more aggressive therapy has not been determined and should be studied. - Utilization of published guidelines and the recommendations from the National - Lipid Association will help to optimize the management of patients with FH. -FAU - Robinson, Jennifer G -AU - Robinson JG -AD - Departments of Epidemilogy & Medicine, Prevention Intervention Center, College of - Public Health, University of Iowa, Iowa City, Iowa, USA. - Jennifer-g-robinson@uiowa.edu -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Manag Care Pharm -JT - Journal of managed care pharmacy : JMCP -JID - 9605854 -RN - 0 (Anticholesteremic Agents) -SB - IM -MH - Age Factors -MH - Anticholesteremic Agents/adverse effects/chemistry/therapeutic use -MH - Cardiovascular Diseases/economics/etiology/prevention & control -MH - Combined Modality Therapy/adverse effects -MH - Cost-Benefit Analysis -MH - Health Care Costs -MH - Humans -MH - Hyperlipoproteinemia Type II/drug therapy/economics/physiopathology/*therapy -MH - *Practice Guidelines as Topic -MH - Risk Factors -MH - Severity of Illness Index -MH - Voluntary Health Agencies -PMC - PMC10438186 -EDAT- 2013/03/07 06:00 -MHDA- 2013/08/22 06:00 -PMCR- 2013/03/01 -CRDT- 2013/03/07 06:00 -PHST- 2013/03/07 06:00 [entrez] -PHST- 2013/03/07 06:00 [pubmed] -PHST- 2013/08/22 06:00 [medline] -PHST- 2013/03/01 00:00 [pmc-release] -AID - 2013(19)2: 139-149 [pii] -AID - 10.18553/jmcp.2013.19.2.139 [doi] -PST - ppublish -SO - J Manag Care Pharm. 2013 Mar;19(2):139-49. doi: 10.18553/jmcp.2013.19.2.139. - -PMID- 21587214 -OWN - NLM -STAT- MEDLINE -DCOM- 20111115 -LR - 20211020 -IS - 1759-5010 (Electronic) -IS - 1759-5002 (Linking) -VI - 8 -IP - 7 -DP - 2011 May 17 -TI - Diagnostic and prognostic value of 3D NOGA mapping in ischemic heart disease. -PG - 393-404 -LID - 10.1038/nrcardio.2011.64 [doi] -AB - The three-dimensional NOGA(®) (Biologics Delivery Systems, a Johnson & Johnson - company, Irwindale, CA, USA) electromechanical mapping system simultaneously - registers the electrical and mechanical activities of the left ventricle, - enabling online assessment of myocardial viability. The system distinguishes - between viable, nonviable, stunned, and hibernating myocardium and can assess - wall motion. The evaluation of the electrophysiological state of the tissue by - NOGA(®) mapping has been validated by comparing the electroanatomical voltage and - local linear shortening maps obtained with this technique with several - noninvasive diagnostic tests. Bipolar signal analysis and determination of the - existence and degree of transmural infarctions are also possible with NOGA(®). - Immediately after percutaneous coronary intervention, an increased - electromechanical discordance between voltage and local linear shortening maps - indicates procedure-induced stunning that is caused by repetitive ischemia or - microvascular compromise. Catheter-based direct intramyocardial injection of - cells or gene constructs by NOGA(®) reduces the likelihood of systemic toxicity - of the injected substance, resulting in minimal washout, limited exposure of - nontarget organs, and precise localization to ischemic and peri-ischemic - myocardial regions in patients with chronic myocardial ischemia. In addition, - direct intramyocardial injection enables the treatment of chronic myocardial - infarction by provoking a chemotactic signal at the injection-injury site that - contributes to cell engraftment. By measuring the electrical activation pattern - in delayed-motion areas, NOGA(®) might also be useful to predict response to - cardiac resynchronization therapy. -CI - © 2011 Macmillan Publishers Limited. All rights reserved -FAU - Gyöngyösi, Mariann -AU - Gyöngyösi M -AD - Department of Cardiology, Medical University of Vienna, Währinger Gürtel 18-20, - A-1090 Vienna, Austria. mariann.gyongyosi@ meduniwien.ac.at -FAU - Dib, Nabil -AU - Dib N -LA - eng -PT - Journal Article -PT - Review -DEP - 20110517 -PL - England -TA - Nat Rev Cardiol -JT - Nature reviews. Cardiology -JID - 101500075 -SB - IM -MH - Angioplasty, Balloon, Coronary -MH - Body Surface Potential Mapping/*instrumentation/methods -MH - Humans -MH - Imaging, Three-Dimensional/*instrumentation -MH - Magnetic Resonance Imaging, Cine -MH - Myocardial Ischemia/*diagnosis/pathology -MH - *Myocardium -MH - Positron-Emission Tomography -MH - Prognosis -MH - Tissue Survival/*physiology -MH - Tomography, Emission-Computed, Single-Photon -EDAT- 2011/05/19 06:00 -MHDA- 2011/11/16 06:00 -CRDT- 2011/05/19 06:00 -PHST- 2011/05/19 06:00 [entrez] -PHST- 2011/05/19 06:00 [pubmed] -PHST- 2011/11/16 06:00 [medline] -AID - nrcardio.2011.64 [pii] -AID - 10.1038/nrcardio.2011.64 [doi] -PST - epublish -SO - Nat Rev Cardiol. 2011 May 17;8(7):393-404. doi: 10.1038/nrcardio.2011.64. - -PMID- 18605997 -OWN - NLM -STAT- MEDLINE -DCOM- 20081103 -LR - 20240117 -IS - 1532-429X (Electronic) -IS - 1097-6647 (Print) -IS - 1097-6647 (Linking) -VI - 10 -IP - 1 -DP - 2008 Jul 7 -TI - Standardized cardiovascular magnetic resonance imaging (CMR) protocols, society - for cardiovascular magnetic resonance: board of trustees task force on - standardized protocols. -PG - 35 -LID - 10.1186/1532-429X-10-35 [doi] -AB - 1. General techniques 1.1. Stress and safety equipment 1.2. Left ventricular (LV) - structure and function module 1.3. Right ventricular (RV) structure and function - module 1.4. Gadolinium dosing module. 1.5. First pass perfusion 1.6. Late - gadolinium enhancement (LGE) 2. Disease specific protocols 2.1. Ischemic heart - disease 2.1.1. Acute myocardial infarction (MI) 2.1.2. Chronic ischemic heart - disease and viability 2.1.3. Dobutamine stress 2.1.4. Adenosine stress perfusion - 2.2. Angiography: 2.2.1. Peripheral magnetic resonance angiography (MRA) 2.2.2. - Thoracic MRA 2.2.3. Anomalous coronary arteries 2.2.4. Pulmonary vein evaluation - 2.3. Other 2.3.1. Non-ischemic cardiomyopathy 2.3.2. Arrhythmogenic right - ventricular cardiomyopathy (ARVC) 2.3.3. Congenital heart disease 2.3.4. Valvular - heart disease 2.3.5. Pericardial disease 2.3.6. Masses -FAU - Kramer, Christopher M -AU - Kramer CM -AD - Departments of Medicine and Radiology, University of Virginia Health System, - Charlottesville, VA, USA. ckramer@virginia.edu -FAU - Barkhausen, Jorg -AU - Barkhausen J -FAU - Flamm, Scott D -AU - Flamm SD -FAU - Kim, Raymond J -AU - Kim RJ -FAU - Nagel, Eike -AU - Nagel E -CN - Society for Cardiovascular Magnetic Resonance Board of Trustees Task Force on - Standardized Protocols -LA - eng -PT - Journal Article -PT - Practice Guideline -PT - Review -DEP - 20080707 -PL - England -TA - J Cardiovasc Magn Reson -JT - Journal of cardiovascular magnetic resonance : official journal of the Society - for Cardiovascular Magnetic Resonance -JID - 9815616 -RN - 0 (Cardiotonic Agents) -RN - 3S12J47372 (Dobutamine) -RN - AU0V1LM3JT (Gadolinium) -SB - IM -MH - Cardiotonic Agents/administration & dosage -MH - Dobutamine/administration & dosage -MH - Gadolinium/administration & dosage -MH - Heart Diseases/*diagnosis -MH - Humans -MH - Magnetic Resonance Angiography/*methods/*standards -MH - Ventricular Function, Left -MH - Ventricular Function, Right -PMC - PMC2467420 -EDAT- 2008/07/09 09:00 -MHDA- 2009/07/29 09:00 -PMCR- 2008/07/07 -CRDT- 2008/07/09 09:00 -PHST- 2008/02/13 00:00 [received] -PHST- 2008/07/07 00:00 [accepted] -PHST- 2008/07/09 09:00 [pubmed] -PHST- 2009/07/29 09:00 [medline] -PHST- 2008/07/09 09:00 [entrez] -PHST- 2008/07/07 00:00 [pmc-release] -AID - S1097-6647(23)01252-8 [pii] -AID - 1532-429X-10-35 [pii] -AID - 10.1186/1532-429X-10-35 [doi] -PST - epublish -SO - J Cardiovasc Magn Reson. 2008 Jul 7;10(1):35. doi: 10.1186/1532-429X-10-35. - -PMID- 21355134 -OWN - NLM -STAT- MEDLINE -DCOM- 20110510 -LR - 20110228 -IS - 0042-4676 (Print) -IS - 0042-4676 (Linking) -IP - 3 -DP - 2010 Jun-Jul -TI - [Tomographic methods in the assessment of myocardial perfusion]. -PG - 10-4 -AB - Myocardium visualization using the most up-to-date tomographic techniques is - extremely important in clinical cardiology. Myocardial viability assessment is of - particular importance in management of patients with Ischemic Heart Disease - (IHD). Although rest echocardiography is the most common in assessment of heart - function, nuclear cardiology (SPECT and PET), and recently cardiac computed - tomography and magnetic resonance become playing important clinical roles. - Determining and understanding of real capabilities of these methods is of great - necessity in this regard. This review examines the current abilities of current - cardiac tomographic modalities for the assessment of myocardial perfusion in - patients with known IHD. -FAU - Sergienko, V B -AU - Sergienko VB -FAU - Ansheles, A A -AU - Ansheles AA -LA - rus -PT - English Abstract -PT - Journal Article -PT - Review -PL - Russia (Federation) -TA - Vestn Rentgenol Radiol -JT - Vestnik rentgenologii i radiologii -JID - 0424741 -SB - IM -MH - *Coronary Circulation -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Myocardial Ischemia/*diagnosis/physiopathology -MH - Reproducibility of Results -MH - Severity of Illness Index -MH - Tomography, Emission-Computed/*methods -MH - Tomography, X-Ray Computed/*methods -EDAT- 2011/03/02 06:00 -MHDA- 2011/05/11 06:00 -CRDT- 2011/03/02 06:00 -PHST- 2011/03/02 06:00 [entrez] -PHST- 2011/03/02 06:00 [pubmed] -PHST- 2011/05/11 06:00 [medline] -PST - ppublish -SO - Vestn Rentgenol Radiol. 2010 Jun-Jul;(3):10-4. - -PMID- 23631236 -OWN - NLM -STAT- MEDLINE -DCOM- 20130822 -LR - 20130501 -IS - 0047-1852 (Print) -IS - 0047-1852 (Linking) -VI - 71 -IP - 3 -DP - 2013 Mar -TI - [Health risks induced by secondhand smoke and declines of risks after - comprehensive smoke-free legislation]. -PG - 464-8 -AB - Secondhand smoke is the major health risk among non-smokers. It is estimated that - more than 6,800 non-smokers who are exposed to secondhand smoke die every year in - Japan. WHO Framework Convention on Tobacco Control requires all the governments - to implement comprehensive smoking ban in order to protect non-smokers' health. - Many countries and municipal offices implemented comprehensive smoking ban in - workplaces and public spaces including restaurants and bars. The number of - patients of acute coronary syndrome and respiratory disease rapidly decreased in - those countries. These facts should be announced to the people and policy makers - where comprehensive smoking ban has not implemented yet in order to protect - non-smokers' health. -FAU - Yamato, Hiroshi -AU - Yamato H -AD - Department of Health Development, Institute of Industrial Ecological Sciences, - University of Occupational and Environmental Health. -LA - jpn -PT - English Abstract -PT - Journal Article -PT - Review -PL - Japan -TA - Nihon Rinsho -JT - Nihon rinsho. Japanese journal of clinical medicine -JID - 0420546 -RN - 0 (Tobacco Smoke Pollution) -SB - IM -MH - Asthma/epidemiology -MH - Guidelines as Topic -MH - Heart Diseases/epidemiology -MH - Humans -MH - Japan -MH - Risk Factors -MH - Smoking/*adverse effects/legislation & jurisprudence -MH - Tobacco Smoke Pollution/*legislation & jurisprudence -EDAT- 2013/05/02 06:00 -MHDA- 2013/08/24 06:00 -CRDT- 2013/05/02 06:00 -PHST- 2013/05/02 06:00 [entrez] -PHST- 2013/05/02 06:00 [pubmed] -PHST- 2013/08/24 06:00 [medline] -PST - ppublish -SO - Nihon Rinsho. 2013 Mar;71(3):464-8. - -PMID- 18720755 -OWN - NLM -STAT- MEDLINE -DCOM- 20080918 -LR - 20190917 -IS - 0370-8179 (Print) -IS - 0370-8179 (Linking) -VI - 136 -IP - 3-4 -DP - 2008 Mar-Apr -TI - [Aortic stenosis: from diagnosis to optimal treatment]. -PG - 176-80 -AB - Aortic stenosis is the most frequent valvular heart disease. Aortic sclerosis is - the first characteristic lesion of the cusps, which is considered today as the - process similar to atherosclerosis. Progression of the disease is an active - process leading to forming of bone matrix and heavily calcified stiff cusps by - inflammatory cells and osteopontin. It is a chronic, progressive disease which - can remain asymptomatic for a long time even in the presence of severe aortic - stenosis. Proper physical examination remains an essential diagnostic tool in - aortic stenosis. Recognition of characteristic systolic murmur draws attention - and guides further diagnosis in the right direction. Doppler echocardiography is - an ideal tool to confirm diagnosis. It is well known that exercise tests help in - stratification risk of asymptomatic aortic stenosis. Serial measurements of brain - natriuretic peptide during a follow-up period may help to identify the optimal - time for surgery. Heart catheterization is mostly restricted to preoperative - evaluation of coronary arteries rather than to evaluation of the valve lesion - itself. Currently, there is no ideal medical treatment for slowing down the - disease progression. The first results about the effect of ACE inhibitors and - statins in aortic sclerosis and stenosis are encouraging, but there is still not - enough evidence. Onset symptoms based on current ACC/AHA/ESC recommendations are - I class indication for aortic valve replacement. Aortic valve can be replaced - with a biological or prosthetic valve. There is a possibility of percutaneous - aortic valve implantation and transapical operation for patients that are - contraindicated for standard cardiac surgery. -FAU - Tavciovski, Dragan -AU - Tavciovski D -FAU - Davicević, Zaklina -AU - Davicević Z -LA - srp -PT - English Abstract -PT - Journal Article -PT - Review -PL - Serbia -TA - Srp Arh Celok Lek -JT - Srpski arhiv za celokupno lekarstvo -JID - 0027440 -SB - IM -MH - *Aortic Valve Stenosis/diagnosis/physiopathology/therapy -MH - Humans -RF - 26 -EDAT- 2008/08/30 09:00 -MHDA- 2008/09/19 09:00 -CRDT- 2008/08/30 09:00 -PHST- 2008/08/30 09:00 [pubmed] -PHST- 2008/09/19 09:00 [medline] -PHST- 2008/08/30 09:00 [entrez] -AID - 10.2298/sarh0804176t [doi] -PST - ppublish -SO - Srp Arh Celok Lek. 2008 Mar-Apr;136(3-4):176-80. doi: 10.2298/sarh0804176t. - -PMID- 23576073 -OWN - NLM -STAT- MEDLINE -DCOM- 20140205 -LR - 20211021 -IS - 1434-9949 (Electronic) -IS - 0770-3198 (Linking) -VI - 32 -IP - 6 -DP - 2013 Jun -TI - Biventricular thrombus and associated myocardial infarction in a rheumatoid - arthritis patient: a case report and literature review. -PG - 909-12 -LID - 10.1007/s10067-013-2231-5 [doi] -AB - Autoimmune diseases including rheumatoid arthritis have an increased incidence of - cardiovascular disease. Rheumatoid arthritis (RA) confers a prothrombotic state - and is associated with venous thrombosis, but its association with arterial - thrombosis and embolism is not clear. In present report, we introduce a unique - case of a 42-year-old woman with RA, who was admitted to the emergency service - with back pain and diagnosed as having large right and left ventricular thrombus - and myocardial infarction, associated with embolization of the thrombus. We also - review the literature about RA and arterial and intraventricular thrombosis. -FAU - Açıkgöz, Eser -AU - Açıkgöz E -AD - Department of Cardiology, Gazi University Faculty of Medicine, Beşevler, 06500 - Ankara, Turkey. dreacikgoz@gmail.com -FAU - Yayla, Cağrı -AU - Yayla C -FAU - Açıkgöz, Sadık Kadri -AU - Açıkgöz SK -FAU - Sahinarslan, Asife -AU - Sahinarslan A -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20130411 -PL - Germany -TA - Clin Rheumatol -JT - Clinical rheumatology -JID - 8211469 -RN - 5Q7ZVV76EI (Warfarin) -SB - IM -MH - Adult -MH - Arthritis, Rheumatoid/*complications/*physiopathology -MH - Coronary Angiography -MH - Echocardiography -MH - Female -MH - Heart Ventricles/*physiopathology -MH - Humans -MH - Myocardial Infarction/*complications/diagnosis/*therapy -MH - Thrombosis/*complications/diagnosis/*therapy -MH - Tomography, X-Ray Computed -MH - Treatment Outcome -MH - Warfarin/therapeutic use -EDAT- 2013/04/12 06:00 -MHDA- 2014/02/06 06:00 -CRDT- 2013/04/12 06:00 -PHST- 2012/12/10 00:00 [received] -PHST- 2013/02/27 00:00 [accepted] -PHST- 2013/02/04 00:00 [revised] -PHST- 2013/04/12 06:00 [entrez] -PHST- 2013/04/12 06:00 [pubmed] -PHST- 2014/02/06 06:00 [medline] -AID - 10.1007/s10067-013-2231-5 [doi] -PST - ppublish -SO - Clin Rheumatol. 2013 Jun;32(6):909-12. doi: 10.1007/s10067-013-2231-5. Epub 2013 - Apr 11. - -PMID- 21675801 -OWN - NLM -STAT- MEDLINE -DCOM- 20111027 -LR - 20131121 -IS - 1179-187X (Electronic) -IS - 1175-3277 (Linking) -VI - 11 -IP - 4 -DP - 2011 Aug 1 -TI - Fenofibrate: a review of its lipid-modifying effects in dyslipidemia and its - vascular effects in type 2 diabetes mellitus. -PG - 227-47 -LID - 10.2165/11207690-000000000-00000 [doi] -AB - Fenofibrate is a fibric acid derivative with lipid-modifying effects that are - mediated by the activation of peroxisome proliferator-activated receptor-α. - Fenofibrate also has a number of nonlipid, pleiotropic effects (e.g. reducing - levels of fibrinogen, C-reactive protein, and various pro-inflammatory markers, - and improving flow-mediated dilatation) that may contribute to its clinical - efficacy, particularly in terms of improving microvascular outcomes. The - beneficial effects of fenofibrate on the lipid profile have been shown in a - number of randomized controlled trials. In primary dyslipidemia, fenofibrate - monotherapy consistently decreased triglyceride (TG) levels to a significantly - greater extent than placebo; significantly greater increases in high-density - lipoprotein cholesterol (HDL-C) levels and significantly greater reductions in - low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) levels - were also seen in some trials. Monotherapy with fenofibrate or gemfibrozil had - generally similar effects on TG and HDL-C levels, although in one trial, TC and - LDL-C levels were reduced to a significantly greater extent with fenofibrate than - with gemfibrozil. Fenofibrate monotherapy tended to improve TG and HDL-C levels - to a significantly greater extent than statin monotherapy in primary - dyslipidemia, whereas statin monotherapy decreased LDL-C and TC levels to a - significantly greater extent than fenofibrate monotherapy. Fenofibrate also had a - beneficial effect on atherogenic dyslipidemia in patients with the metabolic - syndrome or type 2 diabetes mellitus, reducing TG levels, tending to increase - HDL-C levels, and promoting a shift to larger low-density lipoprotein particles. - In terms of cardiovascular outcomes, fenofibrate did not reduce the risk of - coronary heart disease (CHD) events to a greater extent than placebo in patients - with type 2 diabetes in the FIELD trial. However, the risk of some nonfatal - macrovascular events (e.g. nonfatal myocardial infarction, revascularization) and - certain microvascular outcomes (e.g. amputation, first laser therapy for diabetic - retinopathy, progression of albuminuria) was reduced to a significantly greater - extent with fenofibrate than with placebo. Subgroup analysis revealed a - significant reduction in the cardiovascular disease (CVD) event rate among - fenofibrate recipients in the subgroup of patients with marked - hypertriglyceridemia or marked dyslipidemia at baseline. In the ACCORD Lipid - trial, there were no significant differences between patients with type 2 - diabetes and a high risk of CVD events who received fenofibrate plus simvastatin - and those who received placebo plus simvastatin for any of the primary or - secondary cardiovascular outcomes. However, fenofibrate plus simvastatin was of - benefit in patients who had markedly high TG levels and markedly low HDL-C levels - at baseline. In addition, fenofibrate plus simvastatin slowed the progression of - diabetic retinopathy. Fenofibrate is generally well tolerated. Common adverse - events included increases in transaminase levels that were usually transient, - minor, and asymptomatic, and gastrointestinal signs and symptoms. In conclusion, - monotherapy with fenofibrate remains a useful option in patients with - dyslipidemia, particularly in atherogenic dyslipidemia characterized by high TG - and low HDL-C levels. -FAU - Keating, Gillian M -AU - Keating GM -AD - Adis, a Wolters Kluwer Business, Auckland, New Zealand. -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -RN - 0 (Hypolipidemic Agents) -RN - U202363UOS (Fenofibrate) -SB - IM -MH - Animals -MH - Diabetes Mellitus, Type 2/complications/*drug therapy -MH - Diabetic Angiopathies/*drug therapy -MH - Dyslipidemias/*drug therapy/metabolism -MH - Fenofibrate/adverse effects/*pharmacology/*therapeutic use -MH - Humans -MH - Hypolipidemic Agents/adverse effects/*pharmacology/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Treatment Outcome -EDAT- 2011/06/17 06:00 -MHDA- 2011/10/28 06:00 -CRDT- 2011/06/17 06:00 -PHST- 2011/06/17 06:00 [entrez] -PHST- 2011/06/17 06:00 [pubmed] -PHST- 2011/10/28 06:00 [medline] -AID - 10.2165/11207690-000000000-00000 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2011 Aug 1;11(4):227-47. doi: - 10.2165/11207690-000000000-00000. - -PMID- 21305872 -OWN - NLM -STAT- MEDLINE -DCOM- 20110304 -LR - 20161125 -IS - 0392-4203 (Print) -IS - 0392-4203 (Linking) -VI - 81 -IP - 2 -DP - 2010 Sep -TI - CT coronary angiography for the follow-up of coronary stent. -PG - 87-93 -AB - The treatment of coronary artery stenosis has progressively shifted over the past - decades, from surgical (CABG) to percutaneous (PCI and stenting). The recent - introduction of drug-eluting stents further reduced the occurrence of in-stent - re-stenosis (ISR). However, a non-negligible number of patients need - imaging/functional tests when symptoms recur. Multi-Slice CT Coronary Angiography - (CT-CA) is a clinical reality for the evaluation of coronary artery stenosis, but - still under evaluation in the follow-up of coronary stents. Several factors may - impair proper depiction of in-stent lumen even with the most recent CT - equipments. In highly selected populations CT-CA may play a clinical role even - though the performance requirements both from the technical standpoint (i.e., CT - scanner) and from the training (i.e., operators' experience) are still very - demanding. In the meantime CT technology should improve towards higher contrast, - spatial and temporal resolution in order to achieve the results that may be - proper for clinical implementation. -FAU - Cademartiri, Filippo -AU - Cademartiri F -AD - Department of Radiology and Cardiology, University Hospital of Parma, Parma, - Italy. filippocademartiri@hotmail.com -FAU - Maffie, Erica -AU - Maffie E -FAU - Palumbo, Alessandro -AU - Palumbo A -FAU - Martini, Chiara -AU - Martini C -FAU - Aldrovandi, Annachiara -AU - Aldrovandi A -FAU - Ardissino, Diego -AU - Ardissino D -FAU - Brambilla, Valerio -AU - Brambilla V -FAU - Coruzzi, Paolo -AU - Coruzzi P -FAU - Mollet, Nico R -AU - Mollet NR -FAU - Krestin, Gabriel P -AU - Krestin GP -FAU - de Feyter, Pim J -AU - de Feyter PJ -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Acta Biomed -JT - Acta bio-medica : Atenei Parmensis -JID - 101295064 -SB - IM -MH - Algorithms -MH - Angioplasty, Balloon, Coronary/*adverse effects -MH - Coronary Angiography/*methods -MH - Coronary Restenosis/*diagnostic imaging -MH - Follow-Up Studies -MH - Humans -MH - Stents/*adverse effects -MH - Tomography, X-Ray Computed/*methods -EDAT- 2011/02/11 06:00 -MHDA- 2011/03/05 06:00 -CRDT- 2011/02/11 06:00 -PHST- 2011/02/11 06:00 [entrez] -PHST- 2011/02/11 06:00 [pubmed] -PHST- 2011/03/05 06:00 [medline] -PST - ppublish -SO - Acta Biomed. 2010 Sep;81(2):87-93. - -PMID- 19020129 -OWN - NLM -STAT- MEDLINE -DCOM- 20081230 -LR - 20090618 -IS - 1526-7598 (Electronic) -IS - 0003-2999 (Linking) -VI - 107 -IP - 6 -DP - 2008 Dec -TI - Congenital supravalvular aortic stenosis and sudden death associated with - anesthesia: what's the mystery? -PG - 1848-54 -LID - 10.1213/ane.0b013e3181875a4d [doi] -AB - Patients with congenital supravalvular aortic stenosis and associated peripheral - pulmonary artery stenoses, the majority of whom have Williams-Beuren syndrome, - are inherently at risk for development of myocardial ischemia. This is - particularly true in the setting of procedural sedation and anesthesia. The - biventricular hypertrophy that accompanies these lesions increases myocardial - oxygen consumption and compromises oxygen delivery. In addition, these patients - often have direct, multifactorial compromise of coronary blood flow. In this - article, we review both the pathophysiology of congenital supravalvular aortic - stenosis and the literature regarding sudden death in association with sedation - and anesthesia. Recommendations as to preoperative assessment and management of - these patients are made based on the best available evidence. -FAU - Burch, Thomas M -AU - Burch TM -AD - Division of Cardiac Anaesthesia, Department of Anesthesiology, Perioperative and - Pain Medicine, Children's Hospital Boston and Harvard Medical School, Boston, - Massachusetts 02115, USA. -FAU - McGowan, Francis X Jr -AU - McGowan FX Jr -FAU - Kussman, Barry D -AU - Kussman BD -FAU - Powell, Andrew J -AU - Powell AJ -FAU - DiNardo, James A -AU - DiNardo JA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Anesth Analg -JT - Anesthesia and analgesia -JID - 1310650 -SB - IM -CIN - Anesth Analg. 2009 Jul;109(1):286-7; author reply 287. doi: - 10.1213/ane.0b013e3181a7fdfc. PMID: 19535725 -MH - Anesthesia/*adverse effects -MH - Aortic Stenosis, Supravalvular/complications/*congenital/physiopathology -MH - Coronary Circulation -MH - Coronary Stenosis/etiology -MH - Death, Sudden, Cardiac/*etiology -MH - Humans -MH - Myocardial Ischemia/etiology -MH - Williams Syndrome/physiopathology -RF - 36 -EDAT- 2008/11/21 09:00 -MHDA- 2008/12/31 09:00 -CRDT- 2008/11/21 09:00 -PHST- 2008/11/21 09:00 [pubmed] -PHST- 2008/12/31 09:00 [medline] -PHST- 2008/11/21 09:00 [entrez] -AID - 107/6/1848 [pii] -AID - 10.1213/ane.0b013e3181875a4d [doi] -PST - ppublish -SO - Anesth Analg. 2008 Dec;107(6):1848-54. doi: 10.1213/ane.0b013e3181875a4d. - -PMID- 18160363 -OWN - NLM -STAT- MEDLINE -DCOM- 20080221 -LR - 20131121 -IS - 1308-0032 (Electronic) -IS - 1302-8723 (Linking) -VI - 7 Suppl 2 -DP - 2007 Dec -TI - [A current problem in atherothrombotic diseases--aspirin resistance: definition, - mechanisms, determination with laboratory tests and clinical implications]. -PG - 20-6 -AB - Aspirin (acetylsalicylic acid) is a powerful antiplatelet agent used in - prevention of atherothrombotic vascular events. However, antiplatelet effect of - aspirin is not uniform and some patients could not benefit from aspirin. These - patients are clinically called as aspirin resistant or aspirin non-responders. - Aspirin resistance could be determined by: bleeding time, optical aggregometry, - PFA-100 (Platelet Function Analyzer), Ultegra-RPFA (Rapid Platelet Function - Assay), activated aggregation time, whole blood aggregometry, platelet aggregate - ratio, flow cytometry, measurements of platelet surface proteins and blood or - urine thromboxane B2 levels. Mechanisms of aspirin resistance have not been - elucidated yet. There is evidence that aspirin resistance increases clinical - cardiovascular events. Adequate additional therapies may reduce atherothrombotic - risks and major cardiovascular events rate in aspirin resistant subjects. - However, we need further studies to decrease major cardiovascular events risk in - aspirin resistant subjects and to optimize antiplatelet therapy. -FAU - Pamukçu, Burak -AU - Pamukçu B -AD - Istanbul Universitesi, Istanbul Tip Fakültesi, Kardiyoloji Anabilim Dali, - Istanbul, Türkiye. burakpamukcu@ttnet.net.tr -FAU - Oflaz, Hüseyin -AU - Oflaz H -FAU - Nişanci, Yilmaz -AU - Nişanci Y -LA - tur -PT - English Abstract -PT - Journal Article -PT - Review -TT - Aterotrombotik hastaliklarda güncel bir sorun--aspirin direnci: tanimi, oluşum - mekanizmalari, laboratuvar yöntemleri ile belirlenmesi ve klinik sonuçlari. -PL - Turkey -TA - Anadolu Kardiyol Derg -JT - Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology -JID - 101095069 -RN - 0 (Platelet Aggregation Inhibitors) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Aspirin/*administration & dosage/adverse effects -MH - Blood Platelets/drug effects -MH - Coronary Thrombosis/*prevention & control -MH - *Drug Resistance -MH - Humans -MH - Platelet Aggregation/drug effects -MH - Platelet Aggregation Inhibitors/*adverse effects -MH - Platelet Function Tests -RF - 50 -EDAT- 2008/02/09 09:00 -MHDA- 2008/02/22 09:00 -CRDT- 2008/02/09 09:00 -PHST- 2008/02/09 09:00 [pubmed] -PHST- 2008/02/22 09:00 [medline] -PHST- 2008/02/09 09:00 [entrez] -PST - ppublish -SO - Anadolu Kardiyol Derg. 2007 Dec;7 Suppl 2:20-6. - -PMID- 21462790 -OWN - NLM -STAT- MEDLINE -DCOM- 20110516 -LR - 20131121 -IS - 1167-7422 (Print) -IS - 1167-7422 (Linking) -VI - 20 -IP - 112 -DP - 2011 Jan -TI - Adverse effects of cannabis. -PG - 18-23 -AB - Cannabis, Cannabis sativa L., is used to produce a resin that contains high - levels of cannabinoids, particularly delta9-tetrahydrocannabinol (THC), which are - psychoactive substances. Although cannabis use is illegal in France and in many - other countries, it is widely used for its relaxing or euphoric effects, - especially by adolescents and young adults. What are the adverse effects of - cannabis on health? During consumption? And in the long term? Does cannabis - predispose users to the development of psychotic disorders? To answer these - questions, we reviewed the available evidence using the standard Prescrire - methodology. The long-term adverse effects of cannabis are difficult to evaluate. - Since and associated substances, with or without the user's knowledge. Tobacco - and alcohol consumption, and particular lifestyles and behaviours are often - associated with cannabis use. Some traits predispose individuals to the use of - psychoactive substances in general. The effects of cannabis are dosedependent.The - most frequently report-ed adverse effects are mental slowness, impaired reaction - times, and sometimes accentuation of anxiety. Serious psychological disorders - have been reported with high levels of intoxication. The relationship between - poor school performance and early, regular, and frequent cannabis use seems to be - a vicious circle, in which each sustains the other. Many studies have focused on - the long-term effects of cannabis on memory, but their results have been - inconclusive. There do not * About fifteen longitudinal cohort studies that - examined the influence of cannabis on depressive thoughts or suicidal ideation - have yielded conflicting results and are inconclusive. Several longitudinal - cohort studies have shown a statistical association between psychotic illness and - self-reported cannabis use. However, the results are difficult to interpret due - to methodological problems, particularly the unknown reliability of self-reported - data. It has not been possible to establish a causal relationship in either - direction, because of these methodological limitations. In Australia, the marked - increase in cannabis use has not been accompanied by an increased incidence of - schizophrenia. On the basis of the available data, we cannot reach firm - conclusions on whether or not cannabis use causes psychosis. It seems prudent to - inform apparently vulnerable individuals that cannabis may cause acute psychotic - decompensation, especially at high doses. Users can feel dependent on cannabis, - but this dependence is usually psychological. Withdrawal symptoms tend to occur - within 48 hours following cessation of regular cannabis use, and include - increased irritability, anxiety, nervousness, restlessness, sleep difficulties - and aggression. Symptoms subside within 2 to 12 weeks. Driving under the - influence of cannabis doubles the risk of causing a fatal road accident. Alcohol - consumption plays an even greater role. A few studies and a number of isolated - reports suggest that cannabis has a role in the occurrence of cardiovascular - adverse effects, especially in patients with coronary heart disease. Numerous - case-control studies have investigated the role of cannabis in the incidence of - some types of cancer. Its role has not been ruled out, but it is not possible to - determine whether the risk is distinct from that of the tobacco with which it is - often smoked. Studies that have examined the influence of cannabis use on the - clinical course of hepatitis C are inconclusive. Alcohol remains the main toxic - agent that hepatitis C patients should avoid. In practice, the adverse effects of - low-level, recreational cannabis use are generally minor, although they can - apparently be serious in vulnerable individuals. The adverse effects of cannabis - appear overall to be less serious than those of alcohol, in terms of - neuropsychological and somatic effects, accidents and violence. -LA - eng -PT - Journal Article -PT - Review -PL - France -TA - Prescrire Int -JT - Prescrire international -JID - 9439295 -RN - 7J8897W37S (Dronabinol) -MH - Adolescent -MH - Cannabis/*adverse effects/chemistry -MH - Dronabinol/pharmacology -MH - France/epidemiology -MH - Humans -MH - Marijuana Abuse/*complications -MH - Marijuana Smoking/*adverse effects -MH - Time Factors -MH - Young Adult -EDAT- 2011/04/06 06:00 -MHDA- 2011/05/17 06:00 -CRDT- 2011/04/06 06:00 -PHST- 2011/04/06 06:00 [entrez] -PHST- 2011/04/06 06:00 [pubmed] -PHST- 2011/05/17 06:00 [medline] -PST - ppublish -SO - Prescrire Int. 2011 Jan;20(112):18-23. - -PMID- 18344273 -OWN - NLM -STAT- MEDLINE -DCOM- 20080424 -LR - 20161124 -IS - 1748-880X (Electronic) -IS - 0007-1285 (Linking) -VI - 81 -IP - 964 -DP - 2008 Apr -TI - Imaging the heart valves using ECG-gated 64-detector row cardiac CT. -PG - 275-90 -LID - 10.1259/bjr/16301537 [doi] -AB - Multi-detector row cardiac CT imaging demonstrates clinical usefulness in - valvular heart disease, for which CT has not been traditionally used. - Electrocardiographic (ECG)-gated CT coronary angiography also has an established - clinical role with an increasingly solid evidence base, and the same data set in - these patients also provides valuable information about chamber and valvular - structure and function; this information should also be considered when - interpreting cardiac CT and non-ECG gated thoracic imaging. Although true flow - data cannot be achieved using CT, as with echocardiography and MRI, there are a - number of imaging features that may be used when interpreting and inferring valve - pathology. This article discusses the role of currently available imaging - modalities and the rationale for cardiac CT, while focusing on the CT - interpretation of valvular heart disease with respect to the relevant - pathophysiology and management options that have importance to the radiologist. A - suggested method of post-processing image review is provided with reference to a - variety of normal and pathological pictorial illustrations. -FAU - Manghat, N E -AU - Manghat NE -AD - Department of Clinical Radiology, Plymouth NHS Trust, Derriford Hospital, - Plymouth, UK. docnatman@msn.com -FAU - Rachapalli, V -AU - Rachapalli V -FAU - Van Lingen, R -AU - Van Lingen R -FAU - Veitch, A M -AU - Veitch AM -FAU - Roobottom, C A -AU - Roobottom CA -FAU - Morgan-Hughes, G J -AU - Morgan-Hughes GJ -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Br J Radiol -JT - The British journal of radiology -JID - 0373125 -SB - IM -MH - Aortic Valve/diagnostic imaging/physiopathology -MH - Echocardiography -MH - Electrocardiography/*methods -MH - Heart Valve Diseases/*diagnostic imaging/physiopathology -MH - Heart Valve Prosthesis -MH - Humans -MH - Magnetic Resonance Imaging -MH - Mitral Valve/diagnostic imaging/physiopathology -MH - Pulmonary Valve/diagnostic imaging/physiopathology -MH - Tomography, X-Ray Computed/*methods -MH - Tricuspid Valve/diagnostic imaging/physiopathology -RF - 44 -EDAT- 2008/03/18 09:00 -MHDA- 2008/04/25 09:00 -CRDT- 2008/03/18 09:00 -PHST- 2008/03/18 09:00 [pubmed] -PHST- 2008/04/25 09:00 [medline] -PHST- 2008/03/18 09:00 [entrez] -AID - 81/964/275 [pii] -AID - 10.1259/bjr/16301537 [doi] -PST - ppublish -SO - Br J Radiol. 2008 Apr;81(964):275-90. doi: 10.1259/bjr/16301537. - -PMID- 17897016 -OWN - NLM -STAT- MEDLINE -DCOM- 20071107 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 13 -IP - 26 -DP - 2007 -TI - Angiotensin II and the cardiac complications of diabetes mellitus. -PG - 2721-9 -AB - The prevalence of diabetes has reached epidemic proportions in the developed - world and is expect to increase to 5.4% by 2025. This has resulted in an - unprecedented number of patients experiencing the macro- and micro-vascular - complications of diabetes, such as renal, retinal, neurological and cardiac - dysfunction. Premature coronary artery disease and cardiac failure are vastly - over-represented in the diabetic population, with significant morbidity and - mortality. In fact, the rate of cardiac events in patients with diabetes is - equivalent to non-diabetic patients with a previous myocardial infarction. - Epidemiological evidence, combined with the results of large scale trials - blocking the renin-angiotensin system (RAS) have provided data to support the - hypothesis that angiotensin II and its interaction with the metabolic changes - associated with diabetes mellitus is responsible for the pathogenesis of many of - these complications. This review focuses on the role of the RAS and the - development of diabetic cardiac disease. -FAU - Connelly, K A -AU - Connelly KA -AD - University of Melbourne, Department of Medicine, St Vincent's Hospital, 4th floor - Clinical Sciences Building, 29 Regent St Fitzroy 3065, Australia. -FAU - Boyle, A J -AU - Boyle AJ -FAU - Kelly, D J -AU - Kelly DJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 11128-99-7 (Angiotensin II) -SB - IM -MH - Angiotensin II/*antagonists & inhibitors/*biosynthesis/physiology -MH - Animals -MH - Diabetes Complications/complications/drug therapy/epidemiology/*metabolism -MH - Diabetes Mellitus/drug therapy/epidemiology/*metabolism -MH - Heart Diseases/drug therapy/epidemiology/etiology/*metabolism -MH - Humans -MH - Up-Regulation/drug effects/physiology -RF - 117 -EDAT- 2007/09/28 09:00 -MHDA- 2007/11/08 09:00 -CRDT- 2007/09/28 09:00 -PHST- 2007/09/28 09:00 [pubmed] -PHST- 2007/11/08 09:00 [medline] -PHST- 2007/09/28 09:00 [entrez] -AID - 10.2174/138161207781662984 [doi] -PST - ppublish -SO - Curr Pharm Des. 2007;13(26):2721-9. doi: 10.2174/138161207781662984. - -PMID- 24121889 -OWN - NLM -STAT- MEDLINE -DCOM- 20140402 -LR - 20131014 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 14 -IP - 10 -DP - 2013 Oct -TI - [Intracardiac echography in interventional cardiology]. -PG - 650-8 -LID - 10.1714/1335.14831 [doi] -AB - Since its early development, interventional cardiology relies on radiological - imaging to show and describe vascular structures involved in percutaneous - treatment. However, the development of the transcatheter approach to structural - heart disease has highlighted the limits of X-rays in guiding interventions - targeting soft heart tissues because of their low radiological resolution. - Transesophageal echocardiography has thus gained an important role in many - catheterization laboratories that perform percutaneous structural heart disease - interventions. The endorsement of this technique necessarily requires expertise - of echocardiographers and anesthesiologists for endotracheal intubation, thus - increasing the logistic complexity of the procedure. Hence, the idea to apply - ultrasonography directly into the heart, thus the introduction of intracardiac - echography. At present, there are two different technological implementations of - intracardiac echography related to the use of an electronic or mechanical - ultrasonic transducer placed at the tip of a catheter inserted into the cardiac - chambers, most frequently via femoral venous vascular access. In this review, we - describe the potentials, advantages and limits of intracardiac echography, as - well as its operative function, current use, and future developments. -FAU - Sgueglia, Gregory A -AU - Sgueglia GA -FAU - Palombaro, Gianluca -AU - Palombaro G -FAU - Pucci, Edoardo -AU - Pucci E -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - L'ecografia intracardiaca in cardiologia interventistica. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -RN - 0 (Sclerosing Solutions) -RN - 3K9958V90M (Ethanol) -SB - IM -MH - Aortic Aneurysm/therapy -MH - Biopsy/methods -MH - Cardiac Catheterization/*methods -MH - Cardiac Imaging Techniques/economics/instrumentation/*methods -MH - Cardiac Surgical Procedures/methods -MH - Cardiology/*methods -MH - Cardiomyopathy, Hypertrophic/therapy -MH - Cost-Benefit Analysis -MH - Echocardiography/economics/instrumentation/*methods -MH - Endocardium/pathology -MH - Endovascular Procedures -MH - Equipment Design -MH - Ethanol/administration & dosage/therapeutic use -MH - Forecasting -MH - Heart Septal Defects/surgery -MH - Heart Valves/surgery -MH - Humans -MH - Percutaneous Coronary Intervention -MH - Sclerosing Solutions/administration & dosage/therapeutic use -MH - Transducers, Pressure -MH - Ultrasonography, Interventional/economics/instrumentation/*methods -EDAT- 2013/10/15 06:00 -MHDA- 2014/04/03 06:00 -CRDT- 2013/10/15 06:00 -PHST- 2013/10/15 06:00 [entrez] -PHST- 2013/10/15 06:00 [pubmed] -PHST- 2014/04/03 06:00 [medline] -AID - 10.1714/1335.14831 [doi] -PST - ppublish -SO - G Ital Cardiol (Rome). 2013 Oct;14(10):650-8. doi: 10.1714/1335.14831. - -PMID- 23109515 -OWN - NLM -STAT- MEDLINE -DCOM- 20130116 -LR - 20250626 -IS - 1524-4539 (Electronic) -IS - 0009-7322 (Linking) -VI - 126 -IP - 18 -DP - 2012 Oct 30 -TI - Natural history and management of aortocoronary saphenous vein graft aneurysms: a - systematic review of published cases. -PG - 2248-56 -LID - 10.1161/CIRCULATIONAHA.112.101592 [doi] -FAU - Ramirez, F Daniel -AU - Ramirez FD -AD - Divisions of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, - Canada. -FAU - Hibbert, Benjamin -AU - Hibbert B -FAU - Simard, Trevor -AU - Simard T -FAU - Pourdjabbar, Ali -AU - Pourdjabbar A -FAU - Wilson, Kumanan R -AU - Wilson KR -FAU - Hibbert, Rebecca -AU - Hibbert R -FAU - Kazmi, Mustapha -AU - Kazmi M -FAU - Hawken, Steven -AU - Hawken S -FAU - Ruel, Marc -AU - Ruel M -FAU - Labinaz, Marino -AU - Labinaz M -FAU - O'Brien, Edward R -AU - O'Brien ER -LA - eng -PT - Journal Article -PT - Systematic Review -PT - Video-Audio Media -PL - United States -TA - Circulation -JT - Circulation -JID - 0147763 -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Aneurysm/diagnosis/epidemiology/*etiology/surgery/therapy -MH - Atherosclerosis/pathology/surgery -MH - *Coronary Artery Bypass/methods -MH - Diagnostic Imaging -MH - Disease Management -MH - Embolization, Therapeutic -MH - Female -MH - Graft Occlusion, Vascular/etiology/physiopathology -MH - Humans -MH - Incidence -MH - Ischemia/etiology/physiopathology -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/epidemiology/etiology -MH - Postoperative Complications/diagnosis/epidemiology/*etiology/surgery/therapy -MH - Recurrence -MH - Saphenous Vein/*pathology/transplantation -MH - Treatment Outcome -MH - Vasa Vasorum/injuries -EDAT- 2012/10/31 06:00 -MHDA- 2013/01/17 06:00 -CRDT- 2012/10/31 06:00 -PHST- 2012/10/31 06:00 [entrez] -PHST- 2012/10/31 06:00 [pubmed] -PHST- 2013/01/17 06:00 [medline] -AID - 126/18/2248 [pii] -AID - 10.1161/CIRCULATIONAHA.112.101592 [doi] -PST - ppublish -SO - Circulation. 2012 Oct 30;126(18):2248-56. doi: 10.1161/CIRCULATIONAHA.112.101592. - -PMID- 22370770 -OWN - NLM -STAT- MEDLINE -DCOM- 20121024 -LR - 20250626 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 20 -IP - 5 -DP - 2012 Sep-Oct -TI - Newer anticoagulants in cardiovascular disease: a systematic review of the - literature. -PG - 209-21 -LID - 10.1097/CRD.0b013e3182503e2d [doi] -AB - Vitamin K antagonists (VKAs) such as warfarin have traditionally been the major - therapeutic option for anticoagulation in clinical practice. VKAs are effective - and extensively recommended for the prevention of venous and arterial - thromboembolism in cardiovascular disease. Despite its effectiveness, warfarin is - limited by factors such as a narrow therapeutic index, drug-drug interactions, - food interactions, slow onset and offset of action, hemorrhage, and routine - anticoagulation monitoring to maintain therapeutic international normalized - ratio. During the last 2 decades, the approval of anticoagulants, such as - low-molecular-weight heparins, indirect factor Xa inhibitors (eg, fondaparinux), - and direct thrombin inhibitors (eg, argatroban, lepirudin, and desirudin), have - expanded the number of available antithrombotic compounds with additional targets - within the anticoagulation pathway. Although these medications offer several - potential therapeutic advantages, they all require parenteral or subcutaneous - administration and are substantially more expensive than VKAs. Thus, VKAs, - despite several limitations, have remained the major option for most patients - requiring chronic anticoagulation. These limitations have prompted interest in - the development of newer oral anticoagulants. Novel anticoagulants targeting - inhibition of factor Xa and thrombin (factor IIa) have now been incorporated into - clinical practice based on the results of large randomized clinical trials, with - the recent U.S. Food and Drug Administration approval of dabigatran for stroke - prevention in atrial fibrillation and rivaroxaban for deep vein thrombosis and - stroke prevention in atrial fibrillation, with multiple other agents in various - stages of development for these and other indications. This review discusses the - pharmacological properties, clinical results, and therapeutic applications of - novel and new anticoagulants, thereby providing an outline for the future of - anticoagulation in cardiovascular disease. -FAU - Maan, Abhishek -AU - Maan A -AD - Department of Medicine, University of Massachusetts Medical School, Worcester, - MA, USA. -FAU - Padmanabhan, Ram -AU - Padmanabhan R -FAU - Shaikh, Amir Y -AU - Shaikh AY -FAU - Mansour, Moussa -AU - Mansour M -FAU - Ruskin, Jeremy N -AU - Ruskin JN -FAU - Heist, E Kevin -AU - Heist EK -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Anticoagulants) -RN - 0 (Antithrombins) -RN - 0 (Factor Xa Inhibitors) -SB - IM -MH - Acute Coronary Syndrome/drug therapy -MH - Administration, Oral -MH - Anticoagulants/pharmacokinetics/*therapeutic use -MH - Antithrombins/pharmacokinetics/therapeutic use -MH - Atrial Fibrillation/drug therapy -MH - Cardiovascular Diseases/*drug therapy -MH - Drug Design -MH - Drug Discovery/trends -MH - Factor Xa Inhibitors -MH - Heart Valve Prolapse -MH - Humans -MH - Randomized Controlled Trials as Topic -MH - Stroke/prevention & control -MH - Venous Thrombosis/drug therapy -EDAT- 2012/03/01 06:00 -MHDA- 2012/10/25 06:00 -CRDT- 2012/02/29 06:00 -PHST- 2012/02/29 06:00 [entrez] -PHST- 2012/03/01 06:00 [pubmed] -PHST- 2012/10/25 06:00 [medline] -AID - 10.1097/CRD.0b013e3182503e2d [doi] -PST - ppublish -SO - Cardiol Rev. 2012 Sep-Oct;20(5):209-21. doi: 10.1097/CRD.0b013e3182503e2d. - -PMID- 22022769 -OWN - NLM -STAT- MEDLINE -DCOM- 20120727 -LR - 20191027 -IS - 1875-6212 (Electronic) -IS - 1570-1611 (Linking) -VI - 10 -IP - 3 -DP - 2012 May -TI - The effects of newer beta-adrenoceptor antagonists on vascular function in - cardiovascular disease. -PG - 378-90 -AB - This review provides a systematic overview of the influence of the third - generation beta-adrenoceptor antagonists on vascular and/or endothelial function - at a cellular level as well as of the advantages of their application in - hypertension, heart failure and coronary artery disease. Drugs antagonizing the - beta-adrenoceptors have been in use for the treatment of hypertension for - decades. In systolic heart failure and post-myocardial infarction, - beta-adrenoceptor antagonists were proven to be effective in decreasing the - number of deaths and improving morbidity. However, betaadrenoceptor antagonists - are a heterogeneous drug group, consisting of agents with different selectivity - for adrenoceptors and/or additional effects in heart and peripheral circulation. - Beta-adrenoceptor antagonists comprise a multitude of different agents, which may - have additional properties exceeding the pure receptor blockade. These features - may provide additional benefit in the treatment of hypertension. The third - generation drug nebivolol exerts a nitric oxide-mediated vasodilating activity - which has positive effects on intima and media thickness and arterial rigidity, a - major risk factor in cardiovascular disease. Moreover, anti-proliferative, - anti-inflammatory, and anti-oxidative properties have been detected for - carvedilol and nebivolol, contributing to their additional value in treatment of - hypertension and heart failure. -FAU - Wehland, Markus -AU - Wehland M -AD - Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, - Magdeburg, Germany. -FAU - Grosse, Jirka -AU - Grosse J -FAU - Simonsen, Ulf -AU - Simonsen U -FAU - Infanger, Manfred -AU - Infanger M -FAU - Bauer, Johann -AU - Bauer J -FAU - Grimm, Daniela -AU - Grimm D -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Vasc Pharmacol -JT - Current vascular pharmacology -JID - 101157208 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Benzopyrans) -RN - 0 (Carbazoles) -RN - 0 (Ethanolamines) -RN - 0 (Propanolamines) -RN - 030Y90569U (Nebivolol) -RN - 0K47UL67F2 (Carvedilol) -RN - 31C4KY9ESH (Nitric Oxide) -SB - IM -MH - Adrenergic beta-Antagonists/*pharmacology/therapeutic use -MH - Animals -MH - Benzopyrans/pharmacology/therapeutic use -MH - Carbazoles/pharmacology/therapeutic use -MH - Cardiovascular Diseases/*drug therapy/physiopathology -MH - Carvedilol -MH - Ethanolamines/pharmacology/therapeutic use -MH - Heart Failure/drug therapy/physiopathology -MH - Humans -MH - Hypertension/drug therapy/physiopathology -MH - Nebivolol -MH - Nitric Oxide/metabolism -MH - Propanolamines/pharmacology/therapeutic use -MH - Risk Factors -MH - Vasodilation/*drug effects -EDAT- 2011/10/26 06:00 -MHDA- 2012/07/28 06:00 -CRDT- 2011/10/26 06:00 -PHST- 2011/04/12 00:00 [received] -PHST- 2011/08/29 00:00 [revised] -PHST- 2011/09/13 00:00 [accepted] -PHST- 2011/10/26 06:00 [entrez] -PHST- 2011/10/26 06:00 [pubmed] -PHST- 2012/07/28 06:00 [medline] -AID - BSP/CVP/E-Pub/0000176 [pii] -AID - 10.2174/157016112799959323 [doi] -PST - ppublish -SO - Curr Vasc Pharmacol. 2012 May;10(3):378-90. doi: 10.2174/157016112799959323. - -PMID- 16980724 -OWN - NLM -STAT- MEDLINE -DCOM- 20071113 -LR - 20060918 -IS - 1462-0332 (Electronic) -IS - 1462-0324 (Linking) -VI - 45 Suppl 4 -DP - 2006 Oct -TI - Nailfold capillaroscopy is useful for the diagnosis and follow-up of autoimmune - rheumatic diseases. A future tool for the analysis of microvascular heart - involvement? -PG - iv43-6 -AB - Raynaud's phenomenon (RP) represents the most frequent clinical aspect of - cardio/microvascular involvement and is a key feature of several autoimmune - rheumatic diseases. Moreover, RP is associated in a statistically significant - manner with many coronary diseases. In normal conditions or in primary RP - (excluding during the cold-exposure test), the normal nailfold capillaroscopic - pattern shows a regular disposition of the capillary loops along with the - nailbed. On the contrary, in subjects suffering from secondary RP, one or more - alterations of the capillaroscopic findings should alert the physician of the - possibility of a connective tissue disease not yet detected. Nailfold - capillaroscopy (NV) represents the best method to analyse microvascular - abnormalities in autoimmune rheumatic diseases. Architectural disorganization, - giant capillaries, haemorrhages, loss of capillaries, angiogenesis and avascular - areas characterize >95% of patients with overt scleroderma (SSc). The term 'SSc - pattern' includes, all together, these sequential capillaroscopic changes typical - to the microvascular involvement in SSc. The capillaroscopic aspects observed in - dermatomyositis and in the undifferentiated connective tissue disease are - generally reported as 'SSc-like pattern'. Effectively, and early in the disease, - the peripheral microangiopathy may be well recognized and studied by nailfold - capillaroscopy, or better with nailfold video capillaroscopy (NVC). The early - differential diagnosis between primary and secondary RP is the best advantage NVC - may offer. In addition, interesting capillaroscopic changes have been observed in - systemic lupus erythematosus, anti-phospholipid syndrome and Sjogren's syndrome. - Further epidemiological and clinical studies are needed to better standardize the - NCV patterns. In future, the evaluation of nailfold capillaroscopy in autoimmune - rheumatic diseases might represent a tool for the prediction of microvascular - heart involvement by considering the systemic microvascular derangement at the - capillary nailfold. -FAU - Cutolo, M -AU - Cutolo M -AD - Research Laboratory and Division of Rheumatology, Department of Internal - Medicine, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy. - mcutolo@unige.it -FAU - Sulli, A -AU - Sulli A -FAU - Secchi, M E -AU - Secchi ME -FAU - Paolino, S -AU - Paolino S -FAU - Pizzorni, C -AU - Pizzorni C -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Rheumatology (Oxford) -JT - Rheumatology (Oxford, England) -JID - 100883501 -SB - IM -MH - Autoimmune Diseases/complications/*diagnosis/physiopathology -MH - Capillaries/pathology -MH - Heart Diseases/*diagnosis/etiology/physiopathology -MH - Humans -MH - *Microscopic Angioscopy -MH - Nails/*blood supply -MH - Rheumatic Diseases/complications/*diagnosis/physiopathology -RF - 35 -EDAT- 2006/09/19 09:00 -MHDA- 2007/11/14 09:00 -CRDT- 2006/09/19 09:00 -PHST- 2006/09/19 09:00 [pubmed] -PHST- 2007/11/14 09:00 [medline] -PHST- 2006/09/19 09:00 [entrez] -AID - 45/suppl_4/iv43 [pii] -AID - 10.1093/rheumatology/kel310 [doi] -PST - ppublish -SO - Rheumatology (Oxford). 2006 Oct;45 Suppl 4:iv43-6. doi: - 10.1093/rheumatology/kel310. - -PMID- 17588878 -OWN - NLM -STAT- MEDLINE -DCOM- 20070718 -LR - 20070625 -IS - 0895-2841 (Print) -IS - 0895-2841 (Linking) -VI - 19 -IP - 1-2 -DP - 2007 -TI - Women, aging, and alcohol use disorders. -PG - 31-48 -AB - The increase in prevalence rates of alcohol use disorders in younger versus older - cohorts of female drinkers is many times higher than the corresponding increase - in prevalence rates for male drinkers. Thus, the number and impact of older - female drinkers is expected to increase over the next 20 years as the disparity - between men's and women's drinking rates decrease. Due to differences in - metabolism of alcohol, women of all ages compared to men are at higher risk for - negative physical, medical, social, and psychological consequences associated - with at-risk and higher levels of alcohol consumption. Aging women face new sets - of antecedents related to challenges in the middle and older adult phases of - life, such as menopause, retirement, "empty nest," limited mobility, and illness. - As women age, they are subject to an even greater physiological susceptibility to - alcohol's effect, as well as to a risk of synergistic effects of alcohol in - combination with prescription drugs. On the other hand, there is mixed research - indicating that older women may benefit from the buffering effect of low levels - of alcohol on hormonal declines associated with menopause, perhaps serving as a - protective factor against Coronary Heart Disease and osteoporosis. However, with - heavier drinking, these benefits are either reversed or eclipsed. In addition, - any alcohol consumption increases the risk for breast cancer in older women. The - possible beneficial effects of alcohol must be weighed with the fact that the - research does not typically establish causality, that low-risk drinking equates - to one standard drink per day, that there is a risk of progression towards - alcohol dependence, and that there are alternate methods to gain the same - benefits without the associated risks. Older women also experience unique - barriers to detection of and treatment for alcohol problems. Current treatment - options specifically for older women are limited, though researchers are - beginning to address differential treatment response of older women, as well as - development of elder women-specific treatment approaches. Treatment options - include self-help/mutual peer support, which provides ancillary advantages, brief - interventions in primary care settings, which have been demonstrated to be - effective in reducing drinking levels, and cognitive behavioral techniques, which - have been demonstrated to be useful; but more studies and larger samples are - needed. Elder-specific treatments need to be appropriate in terms of content, to - address the challenges associated with life stage, such as the loss of the - parental role and widowhood, and in terms of process, such as delivery in a - respectful therapeutic style and at a slower pace. Future directions in research - should address the lack of assessment instruments, the risks of simultaneous use - of alcohol and prescription medications, and the under-representation of older - women in randomized trials of alcohol treatments. -FAU - Epstein, Elizabeth E -AU - Epstein EE -AD - Center of Alcohol Studies, Rutgers-The State University of New Jersey, - Piscataway, NJ 08854, USA. bepstein@rci.rutgers.edu -FAU - Fischer-Elber, Kimberly -AU - Fischer-Elber K -FAU - Al-Otaiba, Zayed -AU - Al-Otaiba Z -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - J Women Aging -JT - Journal of women & aging -JID - 8916635 -SB - IM -MH - *Aging -MH - Alcohol Drinking/*epidemiology/prevention & control -MH - Alcoholism/*epidemiology/prevention & control -MH - Anxiety Disorders/epidemiology -MH - Depressive Disorder/epidemiology -MH - Female -MH - *Health Knowledge, Attitudes, Practice -MH - Humans -MH - Prevalence -MH - Primary Prevention/*organization & administration -MH - Sex Distribution -MH - Social Adjustment -MH - Socioeconomic Factors -MH - *Women's Health -MH - Women's Health Services/organization & administration -RF - 72 -EDAT- 2007/06/26 09:00 -MHDA- 2007/07/19 09:00 -CRDT- 2007/06/26 09:00 -PHST- 2007/06/26 09:00 [pubmed] -PHST- 2007/07/19 09:00 [medline] -PHST- 2007/06/26 09:00 [entrez] -AID - 10.1300/J074v19n01_03 [doi] -PST - ppublish -SO - J Women Aging. 2007;19(1-2):31-48. doi: 10.1300/J074v19n01_03. - -PMID- 24296264 -OWN - NLM -STAT- MEDLINE -DCOM- 20141003 -LR - 20211203 -IS - 1873-3492 (Electronic) -IS - 0009-8981 (Linking) -VI - 429 -DP - 2014 Feb 15 -TI - NPC1, intracellular cholesterol trafficking and atherosclerosis. -PG - 69-75 -LID - S0009-8981(13)00473-7 [pii] -LID - 10.1016/j.cca.2013.11.026 [doi] -AB - Post-lysosomal cholesterol trafficking is an important, but poorly understood - process that is essential to maintain lipid homeostasis. Niemann-Pick type C1 - (NPC1), an integral membrane protein on the limiting membrane of late - endosome/lysosome (LE/LY), is known to accept cholesterol from NPC2 and then - mediate cholesterol transport from LE/LY to endoplasmic reticulum (ER) and plasma - membrane in a vesicle- or oxysterol-binding protein (OSBP)-related protein 5 - (ORP5)-dependent manner. Mutations in the NPC1 gene can be found in the majority - of NPC patients, who accumulate massive amounts of cholesterol and other lipids - in the LE/LY due to a defect in intracellular lipid trafficking. Liver X receptor - (LXR) is the major positive regulator of NPC1 expression. Atherosclerosis is the - pathological basis of coronary heart disease, one of the major causes of death - worldwide. NPC1 has been shown to play a critical role in the atherosclerotic - progression. In this review, we have summarized the role of NPC1 in regulating - intracellular cholesterol trafficking and atherosclerosis. -CI - Copyright © 2013 Elsevier B.V. All rights reserved. -FAU - Yu, Xiao-Hua -AU - Yu XH -AD - Life Science Research Center, University of South China, Hengyang, Hunan 421001, - China. -FAU - Jiang, Na -AU - Jiang N -AD - Department of Electrocardiogram, the Second Affiliated Hospital, University of - South China, Hengyang, Hunan 421001, China. -FAU - Yao, Ping-Bo -AU - Yao PB -AD - Department of Intensive Care, the Affiliated Nanhua Hospital, University of South - China, Hengyang, Hunan 421001, China. -FAU - Zheng, Xi-Long -AU - Zheng XL -AD - Department of Biochemistry and Molecular Biology, The Libin Cardiovascular - Institute of Alberta, The University of Calgary, Health Sciences Center, 3330 - Hospital Dr NW, Calgary, Alberta, T2N 4 N1, Canada. -FAU - Cayabyab, Francisco S -AU - Cayabyab FS -AD - Department of Physiology, University of Saskatchewan, Saskatoon, Saskatchewan, - Canada. -FAU - Tang, Chao-Ke -AU - Tang CK -AD - Life Science Research Center, University of South China, Hengyang, Hunan 421001, - China; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology - of Hunan Province, University of South China, Hengyang, Hunan 421001, China. - Electronic address: tangchaoke@qq.com. -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131201 -PL - Netherlands -TA - Clin Chim Acta -JT - Clinica chimica acta; international journal of clinical chemistry -JID - 1302422 -RN - 0 (Carrier Proteins) -RN - 0 (Intracellular Signaling Peptides and Proteins) -RN - 0 (Membrane Glycoproteins) -RN - 0 (NPC1 protein, human) -RN - 0 (Niemann-Pick C1 Protein) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Animals -MH - Atherosclerosis/*metabolism/pathology -MH - Biological Transport -MH - Carrier Proteins/chemistry/*metabolism -MH - Cholesterol/*metabolism -MH - Humans -MH - Intracellular Signaling Peptides and Proteins -MH - Intracellular Space/*metabolism -MH - Membrane Glycoproteins/chemistry/*metabolism -MH - Niemann-Pick C1 Protein -MH - Niemann-Pick Diseases/metabolism/pathology -OTO - NOTNLM -OT - ABCA1 -OT - ATP-binding cassette transporter A1 -OT - Atherosclerosis -OT - COX-2 -OT - Cholesterol -OT - DHC -OT - ER -OT - ERK1/2 -OT - LDL -OT - LDL-C -OT - LDL-cholesterol -OT - LDLR -OT - LE/LY -OT - LXR -OT - N-terminal domain -OT - NPC1 -OT - NPC2 -OT - NTD -OT - Niemann-Pick type C1 -OT - ORP5 -OT - OSBP -OT - OSBP­related protein 5 -OT - PPARα -OT - SREBP -OT - SSD -OT - TGN -OT - apoA-I -OT - apoE -OT - apolipoprotein A-I -OT - apolipoprotein E -OT - cyclooxygenase-2 -OT - dihydrocapsaicin -OT - endoplasmic reticulum -OT - extracellular signal-regulated kinase 1/2 -OT - late endosome/lysosome -OT - liver X receptor -OT - low-density lipoprotein -OT - low-density lipoprotein receptor -OT - oxLDL -OT - oxidized low-density lipoprotein -OT - oxysterol­binding protein -OT - peroxisome proliferator-activated receptor α -OT - sterol regulatory element-binding protein -OT - sterol-sensing domain -OT - trans-Golgi network -EDAT- 2013/12/04 06:00 -MHDA- 2014/10/04 06:00 -CRDT- 2013/12/04 06:00 -PHST- 2013/09/27 00:00 [received] -PHST- 2013/11/17 00:00 [revised] -PHST- 2013/11/23 00:00 [accepted] -PHST- 2013/12/04 06:00 [entrez] -PHST- 2013/12/04 06:00 [pubmed] -PHST- 2014/10/04 06:00 [medline] -AID - S0009-8981(13)00473-7 [pii] -AID - 10.1016/j.cca.2013.11.026 [doi] -PST - ppublish -SO - Clin Chim Acta. 2014 Feb 15;429:69-75. doi: 10.1016/j.cca.2013.11.026. Epub 2013 - Dec 1. - -PMID- 23226021 -OWN - NLM -STAT- MEDLINE -DCOM- 20130521 -LR - 20211021 -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Print) -IS - 1176-6344 (Linking) -VI - 8 -DP - 2012 -TI - Mipomersen and other therapies for the treatment of severe familial - hypercholesterolemia. -PG - 651-9 -LID - 10.2147/VHRM.S28581 [doi] -AB - Familial hypercholesterolemia (FH) is an autosomal dominant condition with a - population prevalence of one in 300-500 (heterozygous) that is characterized by - high levels of low-density lipoprotein (LDL) cholesterol, tendon xanthomata, and - premature atherosclerosis and coronary heart disease (CHD). FH is caused mainly - by mutations in the LDLR gene. However, mutations in other genes including APOB - and PCSK9, can give rise to a similar phenotype. Homozygous FH with an estimated - prevalence of one in a million is associated with severe hypercholesterolemia - with accelerated atherosclerotic CHD in childhood and without treatment, death - usually occurs before the age of 30 years. Current approaches for the treatment - of homozygous FH include statin-based lipid-lowering therapies and LDL apheresis. - Mipomersen is a second-generation antisense oligonucleotide (ASO) targeted to - human apolipoprotein B (apoB)-100. This review provides an overview of the - pathophysiology and current treatment options for familial hypercholesterolemia - and describes novel therapeutic strategies focusing on mipomersen, an antisense - apoB synthesis inhibitor. Mipomersen is distributed mainly to the liver where it - silences apoB mRNA, thereby reducing hepatic apoB-100 and giving rise to - reductions in plasma total cholesterol, LDL-cholesterol, and apoB concentrations - in a dose-and time-dependent manner. Mipomersen has been shown to decrease apoB, - LDL-cholesterol and lipoprotein(a) in patients with heterozygous and homozygous - FH on maximally tolerated lipid-lowering therapy. The short-term efficacy and - safety of mipomersen has been established, however, injection site reactions are - common and concern exists regarding the long-term potential for hepatic steatosis - with this ASO. In summary, mipomersen given alone or in combination with standard - lipid-lowering medications shows promise as an adjunct therapy in patients with - homozygous or refractory heterozygous FH at high risk of atherosclerotic CHD, who - are not at target or are intolerant of statins. -FAU - Bell, Damon A -AU - Bell DA -AD - Department of Core Clinical Pathology and Biochemistry, PathWest Laboratory - Medicine, Royal Perth Hospital, Perth, Western Australia, Australia. -FAU - Hooper, Amanda J -AU - Hooper AJ -FAU - Watts, Gerald F -AU - Watts GF -FAU - Burnett, John R -AU - Burnett JR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121128 -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Apolipoproteins B) -RN - 0 (Biomarkers) -RN - 0 (Cholesterol, LDL) -RN - 0 (Oligodeoxyribonucleotides, Antisense) -RN - 0 (Oligonucleotides) -RN - 97C5T2UQ7J (Cholesterol) -RN - 9GJ8S4GU0M (mipomersen) -SB - IM -MH - Anticholesteremic Agents/adverse effects/*therapeutic use -MH - Apolipoproteins B/biosynthesis/genetics -MH - Biomarkers/blood -MH - Cholesterol/*blood -MH - Cholesterol, LDL/blood -MH - Dose-Response Relationship, Drug -MH - Humans -MH - Hyperlipoproteinemia Type II/blood/diagnosis/*drug therapy/epidemiology/genetics -MH - Liver/drug effects/metabolism -MH - Oligodeoxyribonucleotides, Antisense/adverse effects/*therapeutic use -MH - Oligonucleotides/adverse effects/*therapeutic use -MH - Prevalence -MH - Time Factors -MH - Treatment Outcome -PMC - PMC3513909 -OTO - NOTNLM -OT - LDL-cholesterol -OT - antisense oligonucleotide -OT - apolipoprotein B -OT - familial hypercholesterolemia -OT - metabolism -OT - mipomersen -EDAT- 2012/12/12 06:00 -MHDA- 2013/05/23 06:00 -PMCR- 2012/11/28 -CRDT- 2012/12/11 06:00 -PHST- 2012/12/11 06:00 [entrez] -PHST- 2012/12/12 06:00 [pubmed] -PHST- 2013/05/23 06:00 [medline] -PHST- 2012/11/28 00:00 [pmc-release] -AID - vhrm-8-651 [pii] -AID - 10.2147/VHRM.S28581 [doi] -PST - ppublish -SO - Vasc Health Risk Manag. 2012;8:651-9. doi: 10.2147/VHRM.S28581. Epub 2012 Nov 28. - -PMID- 17119268 -OWN - NLM -STAT- MEDLINE -DCOM- 20070208 -LR - 20181201 -IS - 0125-9326 (Print) -IS - 0125-9326 (Linking) -VI - 38 -IP - 3 -DP - 2006 Jul-Sep -TI - New approach in the treatment of T2DM and metabolic syndrome (focus on a novel - insulin sensitizer). -PG - 160-6 -AB - Peroxisome Proliferator-Activate Receptors (PPARs) are transcription factors - belonging to the nuclear receptor superfamily. The three PPARs (alpha, - beta/delta, and gamma) are distributed differently in the different organs. - PPARalpha is most common in the liver, but also found in kidney, gut, skeletal - muscle and adipose tissue, while PPARbeta/delta, is fairly ubiquitous; it may be - found in body tissues and brain (for myelination process and lipid metabolism in - the brain). PPARgamma has 3 isoforms, such as PPARgamma 1, PPARgamma 2, and - PPARgamma 3. The syndrome-X was firstly coined by Reaven in 1988 and then to be - provided in 1999 by the name : the metabolic syndrome-X. This metabolic syndrome - represents a "Cluster" of metabolic disorders and cardiovascular risk factors - which has been collected and summarized by the author and such a cluster - includes: insulin resistance/hyperinsulinemia, central obesity, glucose - intolerance/DM, atherogenic dyslipidemia (increase TG, decrease HDL-cholesterol, - increase Apo-B, increase small dense LDL), hypertension, prothrombotic state - (increase PAI-1, increase F-VII, increase fibrinogen, increase vWF, increase - adhesion molecules), endothelial dysfunction, hyperuricemia, and increased hsC-RP - and cytokines. The metabolic syndrome-X may lead to the development of T2DM and - coronary heart disease (CHD); insulin resistance plays pivotal roles in the - progression of such a syndrome and cardiovascular diseases. Improvement of - Insulin Resistance, therefore, is most likely to reduce the high cardiovascular - event rate in T2DM. It has been generally accepted that Insulin Resistance - (detected by HOMA-R) and Acute Insulin Response = AIR (by HOMA-B) are both - usually present in T2DM. The Thiazolidinedions (TZDs) are Insulin Sensitizers - (e.g Rosiglitazone = ROS, Pioglitazone = PIO) introduced into clinical practice - in 1997; clinical evidence data showed that TZDs improved both HOMA-R, and - HOMA-B. PPARgamma can be activated by TZDs and it appears to be fundamental to - the pathophysiology of diabetes mellitus i.e increase GLUT-4, increase - glucokinase, decrease PEPCK, increase GLUT-4, and decreases production by fat - cell of several mediators that may cause insulin resistance, such as TNFalpha and - resistin. PPARgamma also mediates increased production of Adiponectin and the - insulin signaling intermediate PI3K, and both actions lead to increase insulin - sensitivity. A "dual PPARgamma-PPARalpha agonists" (e.g PIO, but ROS poorly - activate PPARalpha) might lower glucose and modulate lipids. Thus, PIO, as a - stronger "dual PPARgamma-PPARalpha agonists", shows an important therapeutic - pathway in diabetes mellitus and cardiovascular diseases, even in metabolic - syndrome. Current evidence suggests a close relationship between activation of - PPARgamma and restoration of insulin sensitivity by reductions in TNFalpha and - FFAs, and the enhancement of insulin stimulation of PI3-K Pathway and also - increase adiponectin & decrease resistin. -FAU - Tjokroprawiro, Askandar -AU - Tjokroprawiro A -AD - Diabetes and Nutrition Center, Dr. Soetomo Teaching Hospital-Airlangga - University, Faculty of Medicine, Surabaya. -LA - eng -PT - Journal Article -PT - Review -PL - Indonesia -TA - Acta Med Indones -JT - Acta medica Indonesiana -JID - 7901042 -RN - 0 (Hypoglycemic Agents) -RN - 0 (PPAR gamma) -RN - 0 (Thiazolidinediones) -RN - 05V02F2KDG (Rosiglitazone) -RN - X4OV71U42S (Pioglitazone) -SB - IM -MH - Diabetes Mellitus, Type 2/complications/*drug therapy -MH - Humans -MH - Hypoglycemic Agents/pharmacology/*therapeutic use -MH - Insulin Resistance/physiology -MH - Metabolic Syndrome/complications/*drug therapy -MH - PPAR gamma/agonists -MH - Pioglitazone -MH - Rosiglitazone -MH - Thiazolidinediones/pharmacology/therapeutic use -RF - 40 -EDAT- 2006/11/23 09:00 -MHDA- 2007/02/09 09:00 -CRDT- 2006/11/23 09:00 -PHST- 2006/11/23 09:00 [pubmed] -PHST- 2007/02/09 09:00 [medline] -PHST- 2006/11/23 09:00 [entrez] -AID - 040579197 [pii] -PST - ppublish -SO - Acta Med Indones. 2006 Jul-Sep;38(3):160-6. - -PMID- 17053529 -OWN - NLM -STAT- MEDLINE -DCOM- 20061130 -LR - 20250623 -IS - 0263-6352 (Print) -IS - 0263-6352 (Linking) -VI - 24 -IP - 11 -DP - 2006 Nov -TI - How strong is the evidence for use of beta-blockers as first-line therapy for - hypertension? Systematic review and meta-analysis. -PG - 2131-41 -AB - OBJECTIVE: To quantify the effect of first-line antihypertensive treatment with - beta-blockers on mortality, morbidity and withdrawal rates, compared with the - other main classes of antihypertensive agents. METHODS: We identified eligible - trials by searching the Cochrane Controlled Trials Register, Medline, Embase, - reference lists of previous reviews, and contacting researchers. We extracted - data independently in duplicate and conducted meta-analysis by analysing trial - participants in groups to which they were randomized, regardless of subsequent - treatment actually received. RESULTS: Thirteen trials with 91,561 participants, - meeting inclusion criteria, compared beta-blockers to placebo (four trials; n = - 23,613), diuretics (five trials; n = 18,241), calcium-channel blockers (CCBs) - (four trials; n = 44,825), and renin-angiotensin system (RAS) inhibitors, namely - angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (three - trials; n = 10,828). Compared to placebo, beta-blockers reduced the risk of - stroke (relative risk 0.80; 95% confidence interval 0.66-0.96) with a marginal - fall in total cardiovascular events (0.88, 0.79-0.97), but did not affect - all-cause mortality (0.99, 0.88-1.11), coronary heart disease (0.93, 0.81-1.07) - or cardiovascular mortality (0.93, 0.80-1.09). The effect on stroke was less than - that of CCBs (1.24, 1.11-1.40) and RAS inhibitors (1.30, 1.11-1.53), and that on - total cardiovascular events less than that of CCBs (1.18, 1.08-1.29). In - addition, patients on beta-blockers were more likely to discontinue treatment - than those on diuretics (1.80; 1.33-2.42) or RAS inhibitors (1.41; 1.29-1.54). - CONCLUSION: Beta-blockers are inferior to CCBs and to RAS inhibitors for reducing - several important hard end points. Compared with diuretics, they had similar - outcomes, but were less well tolerated. Hence beta-blockers are generally - suboptimal first-line antihypertensive drugs. -FAU - Bradley, Hazel A -AU - Bradley HA -AD - School of Public Health, University of the Western Cape, South Africa. -FAU - Wiysonge, Charles Shey -AU - Wiysonge CS -FAU - Volmink, Jimmy A -AU - Volmink JA -FAU - Mayosi, Bongani M -AU - Mayosi BM -FAU - Opie, Lionel H -AU - Opie LH -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - Netherlands -TA - J Hypertens -JT - Journal of hypertension -JID - 8306882 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Antihypertensive Agents) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Diuretics) -SB - IM -MH - Adrenergic beta-Antagonists/adverse effects/*therapeutic use -MH - Antihypertensive Agents/adverse effects/*therapeutic use -MH - Calcium Channel Blockers/therapeutic use -MH - Diuretics/therapeutic use -MH - Humans -MH - Hypertension/complications/*drug therapy -MH - Randomized Controlled Trials as Topic -MH - Renin-Angiotensin System/drug effects -MH - Treatment Outcome -RF - 53 -EDAT- 2006/10/21 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/10/21 09:00 -PHST- 2006/10/21 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/10/21 09:00 [entrez] -AID - 00004872-200611000-00002 [pii] -AID - 10.1097/01.hjh.0000249685.58370.28 [doi] -PST - ppublish -SO - J Hypertens. 2006 Nov;24(11):2131-41. doi: 10.1097/01.hjh.0000249685.58370.28. - -PMID- 22311404 -OWN - NLM -STAT- MEDLINE -DCOM- 20120910 -LR - 20211021 -IS - 1993-0402 (Electronic) -IS - 1672-0415 (Linking) -VI - 18 -IP - 2 -DP - 2012 Feb -TI - Atherosclerosis, vascular aging and therapeutic strategies. -PG - 83-7 -LID - 10.1007/s11655-012-0996-z [doi] -AB - With the arrival of the era of global population aging, we strive for healthy - aging and a healthy senior life rather than simple prolongation of the physical - age. For the past 50 years, cardiovascular diseases (CVD) have been the most - common cause of death among the elderly people globally. In China, there has been - an exponential increase in the incidence of heart disease and stroke in the - elderly population. Atherosclerosis is the pathological change in the coronary - artery disease, stroke, and peripheral vascular disease. Despite the significant - benefit demonstrated, control of classic risk factors alone, such as lifestyle - change or drug therapy, was shown to have limitations in reducing the incidence - of cardiovascular events. Vascular aging has been shown to be an important - independent predictor of CVD events. Interventions targeting vascular aging have - emerged as a new paradigm in conjunction with control of risk factors for the - prevention of CVD. Vascular aging and atherosclerosis are two distinct - pathological changes and difficult to distinguish clinically. Recent research - with Chinese medicine (CM) has shown encouraging observations, linking the - clinical benefit of delaying vascular aging and treating atherosclerosis. These - results demonstrate great potential of CM in the prevention and treatment of CVD. -FAU - Liu, Yue -AU - Liu Y -AD - Cardiovascular Disease Center of Xiyuan Hospital, China Academy of Chinese - Medical Sciences, Beijing, China. -FAU - Chen, Ke-Ji -AU - Chen KJ -LA - eng -PT - Journal Article -PT - Review -DEP - 20120205 -PL - China -TA - Chin J Integr Med -JT - Chinese journal of integrative medicine -JID - 101181180 -SB - IM -MH - Aging/*pathology -MH - Atherosclerosis/*therapy -MH - Blood Vessels/*pathology -MH - Humans -MH - Risk Factors -EDAT- 2012/02/09 06:00 -MHDA- 2012/09/11 06:00 -CRDT- 2012/02/08 06:00 -PHST- 2011/10/03 00:00 [received] -PHST- 2012/02/08 06:00 [entrez] -PHST- 2012/02/09 06:00 [pubmed] -PHST- 2012/09/11 06:00 [medline] -AID - 10.1007/s11655-012-0996-z [doi] -PST - ppublish -SO - Chin J Integr Med. 2012 Feb;18(2):83-7. doi: 10.1007/s11655-012-0996-z. Epub 2012 - Feb 5. - -PMID- 17536159 -OWN - NLM -STAT- MEDLINE -DCOM- 20070911 -LR - 20220309 -IS - 0021-2571 (Print) -IS - 0021-2571 (Linking) -VI - 43 -IP - 1 -DP - 2007 -TI - Engineering aspects of stents design and their translation into clinical - practice. -PG - 89-100 -AB - The implantation of coronary stents is a relevant part of interventional - procedures for percutaneous revascularization. The wide acceptance of coronary - stenting was based on the results of two highly significant trials which have - shown the superiority of stenting over balloon angioplasty in terms of reduction - of angiographic restenosis and need for repeated intervention in focal lesions - and large coronary arteries. Since then, the growing use of stent market was - impressive. A rapidly increasing number of different stent type with different - material and designs has been introduced in the market both for bare metal stent - and drug eluting stent. This review will summarize the different components of - stent design that are important in term of biological response of the arterial - wall and clinical outcome. In addition, new stent platforms, mainly represented - by the biodegradable stent will be shortly reviewed since it may provide in the - near future a more "physiological" answer to stent implantation, reducing - vascular injury and accelerating vessel healing with consequent improving in - clinical outcome. -FAU - Sangiorgi, Giuseppe -AU - Sangiorgi G -AD - Ospedale San Raffaele, Via Olgettina 64, 20132 Milan, Italy. - sangiorgi@emocolumbus.it -FAU - Melzi, Gloria -AU - Melzi G -FAU - Agostoni, Pierfrancesco -AU - Agostoni P -FAU - Cola, Clarissa -AU - Cola C -FAU - Clementi, Fabrizio -AU - Clementi F -FAU - Romitelli, Paolo -AU - Romitelli P -FAU - Virmani, Renu -AU - Virmani R -FAU - Colombo, Antonio -AU - Colombo A -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Ann Ist Super Sanita -JT - Annali dell'Istituto superiore di sanita -JID - 7502520 -RN - 0 (Coated Materials, Biocompatible) -RN - 0 (Drug Implants) -RN - P88XT4IS4D (Paclitaxel) -RN - W36ZG6FT64 (Sirolimus) -SB - IM -MH - Absorbable Implants -MH - Angioplasty, Balloon, Coronary -MH - Clinical Trials as Topic -MH - Coated Materials, Biocompatible -MH - Coronary Stenosis/*therapy -MH - Drug Implants -MH - Equipment Design -MH - Humans -MH - Multicenter Studies as Topic -MH - Paclitaxel/administration & dosage -MH - Sirolimus/administration & dosage -MH - *Stents/adverse effects/classification -MH - Treatment Outcome -RF - 47 -EDAT- 2007/05/31 09:00 -MHDA- 2007/09/12 09:00 -CRDT- 2007/05/31 09:00 -PHST- 2007/05/31 09:00 [pubmed] -PHST- 2007/09/12 09:00 [medline] -PHST- 2007/05/31 09:00 [entrez] -PST - ppublish -SO - Ann Ist Super Sanita. 2007;43(1):89-100. - -PMID- 17186138 -OWN - NLM -STAT- MEDLINE -DCOM- 20071220 -LR - 20181113 -IS - 1569-5794 (Print) -IS - 1569-5794 (Linking) -VI - 23 -IP - 5 -DP - 2007 Oct -TI - A practical guide to reading CT coronary angiograms--how to avoid mistakes when - assessing for coronary stenoses. -PG - 617-33 -AB - There are now many physicians, both radiologists and cardiologists who are - reporting CT coronary angiography (CTCA) scans who may not be aware that there - are many pitfalls present. For the inexperienced reader a significant stenosis in - a coronary artery can be easily missed or a moderate stenosis overcalled as - significant. Artifacts can also be misinterpreted as representing a significant - lesion. It is important that the studies are correctly interpreted, especially as - the reported high negative predictive value of CTCA scans is a major strength of - this imaging technique. The learning curve of reading these scans is steep and - access to conventional coronary catheterisation results is essential for feedback - and to improve the readers results. We have developed some rules to aid beginners - avoid some of the pitfalls that can occur as these studies are not as easy to - read as they may appear initially. -FAU - Hoe, John W M -AU - Hoe JW -AD - Medi-Rad Associates Ltd, CT Centre, Mt Elizabeth Hospital, 3 Mt Elizabeth, - Singapore 288185, Singapore. jhoe@pacific.net.sg -FAU - Toh, Kok Hong -AU - Toh KH -LA - eng -PT - Journal Article -PT - Review -DEP - 20061221 -PL - United States -TA - Int J Cardiovasc Imaging -JT - The international journal of cardiovascular imaging -JID - 100969716 -SB - IM -MH - *Artifacts -MH - Calcinosis/*diagnostic imaging -MH - Coronary Angiography/*methods -MH - Coronary Stenosis/*diagnostic imaging -MH - Decision Trees -MH - Diagnostic Errors/*prevention & control -MH - Humans -MH - Practice Guidelines as Topic -MH - Predictive Value of Tests -MH - *Radiographic Image Interpretation, Computer-Assisted -MH - Reproducibility of Results -MH - Sensitivity and Specificity -MH - Severity of Illness Index -MH - *Tomography, X-Ray Computed -RF - 28 -EDAT- 2006/12/23 09:00 -MHDA- 2007/12/21 09:00 -CRDT- 2006/12/23 09:00 -PHST- 2006/08/18 00:00 [received] -PHST- 2006/09/29 00:00 [accepted] -PHST- 2006/12/23 09:00 [pubmed] -PHST- 2007/12/21 09:00 [medline] -PHST- 2006/12/23 09:00 [entrez] -AID - 10.1007/s10554-006-9173-9 [doi] -PST - ppublish -SO - Int J Cardiovasc Imaging. 2007 Oct;23(5):617-33. doi: 10.1007/s10554-006-9173-9. - Epub 2006 Dec 21. - -PMID- 16700859 -OWN - NLM -STAT- MEDLINE -DCOM- 20060725 -LR - 20220409 -IS - 1368-5031 (Print) -IS - 1368-5031 (Linking) -VI - 60 -IP - 5 -DP - 2006 May -TI - A review of the management of patients after percutaneous coronary intervention. -PG - 582-9 -AB - The exponential increase in the numbers of percutaneous coronary interventions - (PCIs) has led to many clinicians having to care for post-PCI patients. We review - the management of early problems seen in post-PCI patients, such as vascular - access site complications, contrast nephropathy, drug-induced thrombocytopaenia - and chest pain. The management of possible restenosis and the use of stress - testing are discussed. The complications from dual antiplatelet therapy are - addressed. The prognosis of the post-PCI patient, the implications of co-existent - heart failure and the newer technologies of implantable defibrillator and cardiac - resynchronisation therapy are reviewed. We conclude by emphasising the importance - of secondary prevention by risk factor modification as well as the communication - between the clinician and the cardiologist. -FAU - Wong, E M L -AU - Wong EM -AD - Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales - Hospital, Chinese University of Hong Kong, Hong Kong, China. - edmondwong@hotmail.com -FAU - Wu, E B -AU - Wu EB -FAU - Chan, W W M -AU - Chan WW -FAU - Yu, C M -AU - Yu CM -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Int J Clin Pract -JT - International journal of clinical practice -JID - 9712381 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Angioplasty, Balloon, Coronary/*adverse effects/methods -MH - Chest Pain/etiology -MH - Coronary Restenosis/diagnosis -MH - Defibrillators, Implantable -MH - Humans -MH - Platelet Aggregation Inhibitors/administration & dosage -MH - Prognosis -MH - Thrombocytopenia/etiology -RF - 72 -EDAT- 2006/05/17 09:00 -MHDA- 2006/07/26 09:00 -CRDT- 2006/05/17 09:00 -PHST- 2006/05/17 09:00 [pubmed] -PHST- 2006/07/26 09:00 [medline] -PHST- 2006/05/17 09:00 [entrez] -AID - IJCP824 [pii] -AID - 10.1111/j.1368-5031.2006.00824.x [doi] -PST - ppublish -SO - Int J Clin Pract. 2006 May;60(5):582-9. doi: 10.1111/j.1368-5031.2006.00824.x. - -PMID- 23889503 -OWN - NLM -STAT- MEDLINE -DCOM- 20160201 -LR - 20140311 -IS - 1365-2591 (Electronic) -IS - 0143-2885 (Linking) -VI - 47 -IP - 4 -DP - 2014 Apr -TI - Brain injury due to anaphylactic shock: broadening manifestations of Kounis - syndrome. -PG - 309-13 -LID - 10.1111/iej.12152 [doi] -AB - Anaphylactic shock is a real and life threatening medical emergency which is - encountered in every field of medicine. The coronary arteries seem to be the - primary target of anaphylaxis resulting in the development of Kounis syndrome. - Kounis syndrome is a pan-arterial anaphylaxis -associated syndrome affecting - patients of any age, involving numerous and continuously increasing causes, with - broadening clinical manifestations and covering a wide spectrum of mast cell - activation disorders. Recently, Kounis-like syndrome affecting the cerebral - arteries was found to be associated with mast cell activation disorders. In - anaphylactic shock, the decrease of cerebral blood flow is more than what would - be expected from severe arterial hypotension. This is attributed to the early and - direct action of anaphylactic mediators on cerebral vessels. While adrenaline is - a life saving agent in the treatment of anaphylactic shock, it contains sodium - betabisulfite as preservative and should be avoided in sulfite allergic patients. - Potential allergens encountered in endodotic practice include formocresol, zinc - compounds thiurams, sodium dimethyldithiocarbamade, and mercaptobenzothiazole - that might have synergistic action. All these agents together with analgesics, - antibiotics, antiseptics, formaldehyde, latex, local anaesthetics and metals used - in dental practice, in general, can induce anaphylactic shock. Practitioners - should be aware of these consequences. A careful history of previous atopy and - reactions is of paramount importance for safe and effective management. -CI - © 2013 International Endodontic Journal. Published by John Wiley & Sons Ltd. -FAU - Soufras, G D -AU - Soufras GD -AD - Department of Cardiology, 'Saint Andrews' State General Hospital, Patras, Greece. -FAU - Kounis, G N -AU - Kounis GN -FAU - Kounis, N G -AU - Kounis NG -LA - eng -PT - Journal Article -PT - Review -DEP - 20130728 -PL - England -TA - Int Endod J -JT - International endodontic journal -JID - 8004996 -RN - 0 (Formocresols) -RN - 0 (Inflammation Mediators) -RN - 37203-87-5 (formocresol) -MH - Anaphylaxis/*complications -MH - Brain Injuries/*etiology -MH - Coronary Vasospasm/etiology -MH - Formocresols/*adverse effects -MH - Humans -MH - Inflammation Mediators/metabolism -MH - Mast Cells/pathology -MH - Myocardial Infarction/etiology -MH - Root Canal Preparation/*adverse effects -MH - Syndrome -OTO - NOTNLM -OT - Kounis syndrome -OT - adrenaline -OT - anaphylaxis -OT - brain injury -EDAT- 2013/07/31 06:00 -MHDA- 2016/02/02 06:00 -CRDT- 2013/07/30 06:00 -PHST- 2013/04/02 00:00 [received] -PHST- 2013/06/13 00:00 [accepted] -PHST- 2013/07/30 06:00 [entrez] -PHST- 2013/07/31 06:00 [pubmed] -PHST- 2016/02/02 06:00 [medline] -AID - 10.1111/iej.12152 [doi] -PST - ppublish -SO - Int Endod J. 2014 Apr;47(4):309-13. doi: 10.1111/iej.12152. Epub 2013 Jul 28. - -PMID- 18991795 -OWN - NLM -STAT- MEDLINE -DCOM- 20090106 -LR - 20191111 -VI - 3 -IP - 3 -DP - 2008 Nov -TI - Systemic immunosuppressive therapy with oral Sirolimus after bare metal stent - implantation: the missing alternative in the prevention of coronary restenosis - after percutaneous coronary interventions. -PG - 201-8 -AB - In recent years, percutaneous coronary intervention (PCI) with drug eluting - stents (DES) to treat de novo coronary lesions has been associated with a - significant reduction of neointimal hyperplasia and in-stent restenosis. However, - several publications raise concerns about long-term safety of DES, especially - with the emerging anxiety with the problem of late stent thrombosis. Different - registries with DES reported a growing incidence of stent thrombosis up to three - years after stent implantation. In parallel with DES introduction in clinical - practice in the last seven years, we identified six reported observational and - randomized clinical experiences assessing the potential role of oral Sirolimus - therapy in the prevention of coronary restenosis after bare metal stent - implantation. Three observational and three randomized studies were performed - during these years. Several implications were drawn: First, systemic therapy was - given for only 14 days after PCI; minor transient side effects were observed in - 25% of patients and were completely relieved after discontinuation of the drug. - Secondly, angiographic restenosis and late loss are strongly related with - Sirolimus blood concentration during the first week of treatment and were - significantly reduced compared to non therapy. Finally, in the last randomized - study, oral Sirolimus plus bare metal stent were cost saving compared to drug - eluting stents with a trend to better clinical late outcome with the oral - immunosuppressive therapy. The manuscript also reviews recent patents with new - drugs, combination of drugs and DES designs which would improve safety and - efficacy in the restenosis prevention after angioplasty. -FAU - Rodriguez, Alfredo E -AU - Rodriguez AE -AD - Cardiovascular Research Center (CECI), Otamendi Hospital, Buenos Aires School of - Medicine, Buenos Aires, Argentina. rodrigueza@sanatorio-otamendi.com.ar -FAU - Fernandez-Pereira, Carlos -AU - Fernandez-Pereira C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Recent Pat Cardiovasc Drug Discov -JT - Recent patents on cardiovascular drug discovery -JID - 101263805 -RN - 0 (Immunosuppressive Agents) -RN - 0 (Metals) -RN - W36ZG6FT64 (Sirolimus) -SB - IM -MH - Administration, Oral -MH - Angioplasty, Balloon, Coronary/*adverse effects -MH - Coronary Restenosis/*prevention & control -MH - Cost-Benefit Analysis -MH - *Drug-Eluting Stents -MH - Humans -MH - Immunosuppressive Agents/*administration & dosage -MH - Metals/*administration & dosage -MH - Randomized Controlled Trials as Topic -MH - Sirolimus/*administration & dosage -RF - 54 -EDAT- 2008/11/11 09:00 -MHDA- 2009/01/07 09:00 -CRDT- 2008/11/11 09:00 -PHST- 2008/11/11 09:00 [pubmed] -PHST- 2009/01/07 09:00 [medline] -PHST- 2008/11/11 09:00 [entrez] -AID - 10.2174/157489008786263998 [doi] -PST - ppublish -SO - Recent Pat Cardiovasc Drug Discov. 2008 Nov;3(3):201-8. doi: - 10.2174/157489008786263998. - -PMID- 18757996 -OWN - NLM -STAT- MEDLINE -DCOM- 20080915 -LR - 20250624 -IS - 1756-1833 (Electronic) -IS - 0959-8138 (Print) -IS - 0959-8138 (Linking) -VI - 337 -DP - 2008 Aug 29 -TI - Drug eluting and bare metal stents in people with and without diabetes: - collaborative network meta-analysis. -PG - a1331 -LID - 337/aug29_3/a1331 [pii] -LID - 10.1136/bmj.a1331 [doi] -LID - a1331 -AB - OBJECTIVE: To compare the effectiveness and safety of three types of stents - (sirolimus eluting, paclitaxel eluting, and bare metal) in people with and - without diabetes mellitus. DESIGN: Collaborative network meta-analysis. DATA - SOURCES: Electronic databases (Medline, Embase, the Cochrane Central Register of - Controlled Trials), relevant websites, reference lists, conference abstracts, - reviews, book chapters, and proceedings of advisory panels for the US Food and - Drug Administration. Manufacturers and trialists provided additional data. REVIEW - METHODS: Network meta-analysis with a mixed treatment comparison method to - combine direct within trial comparisons between stents with indirect evidence - from other trials while maintaining randomisation. Overall mortality was the - primary safety end point, target lesion revascularisation the effectiveness end - point. RESULTS: 35 trials in 3852 people with diabetes and 10,947 people without - diabetes contributed to the analyses. Inconsistency of the network was - substantial for overall mortality in people with diabetes and seemed to be - related to the duration of dual antiplatelet therapy (P value for interaction - 0.02). Restricting the analysis to trials with a duration of dual antiplatelet - therapy of six months or more, inconsistency was reduced considerably and hazard - ratios for overall mortality were near one for all comparisons in people with - diabetes: sirolimus eluting stents compared with bare metal stents 0.88 (95% - credibility interval 0.55 to 1.30), paclitaxel eluting stents compared with bare - metal stents 0.91 (0.60 to 1.38), and sirolimus eluting stents compared with - paclitaxel eluting stents 0.95 (0.63 to 1.43). In people without diabetes, hazard - ratios were unaffected by the restriction. Both drug eluting stents were - associated with a decrease in revascularisation rates compared with bare metal - stents in people both with and without diabetes. CONCLUSION: In trials that - specified a duration of dual antiplatelet therapy of six months or more after - stent implantation, drug eluting stents seemed safe and effective in people both - with and without diabetes. -FAU - Stettler, Christoph -AU - Stettler C -AD - Institute of Social and Preventive Medicine, University of Bern, 3012 Bern, - Switzerland. -FAU - Allemann, Sabin -AU - Allemann S -FAU - Wandel, Simon -AU - Wandel S -FAU - Kastrati, Adnan -AU - Kastrati A -FAU - Morice, Marie Claude -AU - Morice MC -FAU - Schömig, Albert -AU - Schömig A -FAU - Pfisterer, Matthias E -AU - Pfisterer ME -FAU - Stone, Gregg W -AU - Stone GW -FAU - Leon, Martin B -AU - Leon MB -FAU - de Lezo, José Suárez -AU - de Lezo JS -FAU - Goy, Jean-Jacques -AU - Goy JJ -FAU - Park, Seung-Jung -AU - Park SJ -FAU - Sabaté, Manel -AU - Sabaté M -FAU - Suttorp, Maarten J -AU - Suttorp MJ -FAU - Kelbaek, Henning -AU - Kelbaek H -FAU - Spaulding, Christian -AU - Spaulding C -FAU - Menichelli, Maurizio -AU - Menichelli M -FAU - Vermeersch, Paul -AU - Vermeersch P -FAU - Dirksen, Maurits T -AU - Dirksen MT -FAU - Cervinka, Pavel -AU - Cervinka P -FAU - De Carlo, Marco -AU - De Carlo M -FAU - Erglis, Andrejs -AU - Erglis A -FAU - Chechi, Tania -AU - Chechi T -FAU - Ortolani, Paolo -AU - Ortolani P -FAU - Schalij, Martin J -AU - Schalij MJ -FAU - Diem, Peter -AU - Diem P -FAU - Meier, Bernhard -AU - Meier B -FAU - Windecker, Stephan -AU - Windecker S -FAU - Jüni, Peter -AU - Jüni P -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Network Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -PT - Technical Report -DEP - 20080829 -PL - England -TA - BMJ -JT - BMJ (Clinical research ed.) -JID - 8900488 -RN - P88XT4IS4D (Paclitaxel) -RN - 0 (Platelet Aggregation Inhibitors) -RN - W36ZG6FT64 (Sirolimus) -SB - IM -CIN - BMJ. 2008 Aug 29;337:a1359. doi: 10.1136/bmj.a1359. PMID: 18757997 -MH - Humans -MH - Blood Vessel Prosthesis -MH - *Coronary Restenosis/prevention & control -MH - *Diabetic Angiopathies/drug therapy -MH - Drug-Eluting Stents -MH - Paclitaxel/administration & dosage -MH - *Platelet Aggregation Inhibitors/administration & dosage -MH - Prosthesis Failure -MH - Randomized Controlled Trials as Topic -MH - Sirolimus/administration & dosage -MH - *Stents -PMC - PMC2527175 -COIS- Competing interests: CSt and PJ report receiving unrestricted grants from the - Swiss National Science Foundation. AK receives lecture fees from Bristol-Myers - Squibb, Cordis, GlaxoSmithKline, Lilly, Medtronic, Novartis, and Sanofi-Aventis. - MCM receives lecture fees from Cordis, Boston Scientific, and Abbot, which go to - a research organisation (RCF, Massy, France). AS receives unrestricted grant - support for the Department of Cardiology he chairs from Amersham/General - Electric, Bayerische Forschungsstiftung, Bristol-Myers Squibb, Cordis, Cryocath, - Guidant, Medtronic, Nycomed, and Schering. MEP receives lecture fees from - Medtronic. GWS receives consulting fees from Boston Scientific, Abbott, Guidant, - Xtent, and BMS Imaging, lecture fees from Boston Scientific, Abbott, and - Medtronic, has equity interests in Devax and Xtent, and is a member of the board - of directors of Devax. MBL receives consulting fees from Cordis, Medtronic, - Boston Scientific, and OrbusNeich and has equity interests in Conor, Medinol, and - OrbusNeich. JJG is on the advisory board of Boston Scientific and receives - research grant support from Cordis. SJP receives research grant support from - Cordis. HK receives unrestricted grant support from Cordis. CSp receives - consulting and lecture fees from Cordis, Boston Scientific, Abbot, Lilly, and - Pfizer. MTD receives lecture fees from Boston Scientific. BM receives research - grant support from various stent companies, including Cordis and Boston - Scientific, and is in the speaker bureau for various stent companies, including - Cordis and Boston Scientific. SW receives lecture and consulting fees from Abbot, - Biotronic, Biosensors, Boston Scientific, Cordis, and Medtronic. GWS and MBL are - directors of the Cardiovascular Research Foundation, a public charity affiliated - with Columbia University Medical Center, from which they receive no compensation; - the Cardiovascular Research Foundation receives research or educational funding - from Boston Scientific, Cordis, Sanofi-Aventis, and Bristol-Myers Squibb. -EDAT- 2008/09/02 09:00 -MHDA- 2008/09/16 09:00 -PMCR- 2008/08/29 -CRDT- 2008/09/02 09:00 -PHST- 2008/09/02 09:00 [pubmed] -PHST- 2008/09/16 09:00 [medline] -PHST- 2008/09/02 09:00 [entrez] -PHST- 2008/08/29 00:00 [pmc-release] -AID - 337/aug29_3/a1331 [pii] -AID - stec540997 [pii] -AID - 10.1136/bmj.a1331 [doi] -PST - epublish -SO - BMJ. 2008 Aug 29;337:a1331. doi: 10.1136/bmj.a1331. - -PMID- 17391152 -OWN - NLM -STAT- MEDLINE -DCOM- 20070622 -LR - 20091103 -IS - 1462-8902 (Print) -IS - 1462-8902 (Linking) -VI - 9 -IP - 3 -DP - 2007 May -TI - Diabetes as a risk factor for cardiac conduction defects: a review. -PG - 276-81 -AB - Diabetes mellitus (DM) is a major risk factor for cardiovascular disease and - mortality with increasing prevalence in the ageing population. Coronary artery - disease is the major cardiovascular abnormality in DM patients. Cardiomyopathy - and left ventricular hypertrophy are two other known associated cardiovascular - abnormalities. There are a few non-randomized studies reporting increased - prevalence of cardiac conduction abnormalities, such as right bundle branch block - (RBBB), bifascicular block and high degree atrioventricular (AV)-block but not - left bundle branch block (LBBB), in DM patients. Most clinicians are not aware of - this association, and it is rarely mentioned in the published reviews about - cardiovascular abnormalities in this population. The cause of cardiac conduction - abnormalities in DM patients is not known. If autonomic neuropathy or - DM-associated cardiovascular disease plays a role, it remains unknown. The goal - of this manuscript is to review the current literature about the risk of - conduction abnormalities in DM patients. For this study, Medline, Google and - published books were searched and reviewed for any references that matched - cardiac conduction abnormalities, AV-block, BBB for bundle branch block, LBBB, - RBBB, bifascicular block, autonomic neuropathy and DM. -FAU - Movahed, Mohammad-Reza -AU - Movahed MR -AD - Department of Medicine, Division of Cardiology, University of California, Irvine - Medical Center, Orange, CA 92868-4080, USA. rmovd@aol.com -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Diabetes Obes Metab -JT - Diabetes, obesity & metabolism -JID - 100883645 -SB - IM -MH - Arrhythmias, Cardiac/complications/*physiopathology/prevention & control -MH - Autonomic Nervous System Diseases/complications/*physiopathology -MH - Bundle-Branch Block/complications/physiopathology/prevention & control -MH - Diabetes Complications/*physiopathology -MH - Heart Block/complications/physiopathology/prevention & control -MH - Heart Conduction System/*physiopathology -MH - Humans -MH - Risk Factors -RF - 59 -EDAT- 2007/03/30 09:00 -MHDA- 2007/06/23 09:00 -CRDT- 2007/03/30 09:00 -PHST- 2007/03/30 09:00 [pubmed] -PHST- 2007/06/23 09:00 [medline] -PHST- 2007/03/30 09:00 [entrez] -AID - DOM609 [pii] -AID - 10.1111/j.1463-1326.2006.00609.x [doi] -PST - ppublish -SO - Diabetes Obes Metab. 2007 May;9(3):276-81. doi: 10.1111/j.1463-1326.2006.00609.x. - -PMID- 16325823 -OWN - NLM -STAT- MEDLINE -DCOM- 20060912 -LR - 20131121 -IS - 0021-9150 (Print) -IS - 0021-9150 (Linking) -VI - 186 -IP - 1 -DP - 2006 May -TI - Phytosterols and vascular disease. -PG - 12-9 -AB - Phytosterols or plant sterols have long been known to lower serum cholesterol - concentrations by competing with dietary and biliary cholesterol for intestinal - absorption. Food products containing phytosterols and phytostanols are now - available to assist in lowering blood cholesterol levels. In contrast to these - possibly beneficial effects of plant sterols, a rare genetic condition called - sitosterolemia, an autosomal recessive disorder also known as phytosterolemia, is - characterized by over absorption of phytosterols and premature coronary artery - and aortic valve disease. Phytosterols have also recently been identified in - atheromatous plaque obtained from individuals with apparently normal absorption - of plant sterols raising the possibility that phytosterols are a novel - atherosclerotic risk factor. This article reviews phytosterols and their - relationship to vascular disease. -FAU - Patel, Manoj D -AU - Patel MD -AD - Section of Preventive Cardiology, Division of Cardiology, Henry Low Heart Center, - Hartford Hospital, 80 Seymour Street, Hartford, CT 06102, USA. -FAU - Thompson, Paul D -AU - Thompson PD -LA - eng -PT - Journal Article -PT - Review -DEP - 20051202 -PL - Ireland -TA - Atherosclerosis -JT - Atherosclerosis -JID - 0242543 -RN - 0 (Phytosterols) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -CIN - Atherosclerosis. 2006 Dec;189(2):478. doi: 10.1016/j.atherosclerosis.2006.05.009. - PMID: 16780847 -CIN - Atherosclerosis. 2007 May;192(1):227-9; author reply 230. doi: - 10.1016/j.atherosclerosis.2006.08.019. PMID: 16979175 -MH - Absorption -MH - Cardiovascular Diseases/blood/*prevention & control -MH - Cholesterol/blood -MH - Humans -MH - Phytosterols/pharmacokinetics/*therapeutic use -MH - Prognosis -MH - Risk Factors -RF - 74 -EDAT- 2005/12/06 09:00 -MHDA- 2006/09/13 09:00 -CRDT- 2005/12/06 09:00 -PHST- 2005/10/13 00:00 [received] -PHST- 2005/10/13 00:00 [accepted] -PHST- 2005/12/06 09:00 [pubmed] -PHST- 2006/09/13 09:00 [medline] -PHST- 2005/12/06 09:00 [entrez] -AID - S0021-9150(05)00673-8 [pii] -AID - 10.1016/j.atherosclerosis.2005.10.026 [doi] -PST - ppublish -SO - Atherosclerosis. 2006 May;186(1):12-9. doi: - 10.1016/j.atherosclerosis.2005.10.026. Epub 2005 Dec 2. - -PMID- 17932586 -OWN - NLM -STAT- MEDLINE -DCOM- 20090709 -LR - 20211020 -IS - 0828-282X (Print) -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 23 Suppl B -IP - Suppl B -DP - 2007 Oct -TI - New concepts in valvular hemodynamics: implications for diagnosis and treatment - of aortic stenosis. -PG - 40B-47B -AB - Aortic valve stenosis (AS) is the third-most frequent heart disease after - coronary artery disease and arterial hypertension, and it is associated with a - high incidence of adverse outcomes. Recent data support the notion that AS is not - an isolated disease uniquely limited to the valve. Indeed, AS is frequently - associated with abnormalities of the systemic arterial system, and, in - particular, with reduced arterial compliance, which may have important - consequences for the pathophysiology and clinical outcome of this disease. - Moreover, AS may also be associated with left ventricular systolic dysfunction - and reduced transvalvular flow rate, which pose important challenges with regards - to diagnostic evaluation and clinical decision making in AS patients. Hence, the - assessment of AS severity, as well as its therapeutic management, should be - conducted with the use of a comprehensive evaluation that includes not only the - aortic valve, but also the systemic arterial system and the left ventricle - because these three entities are tightly coupled from both a pathophysiological - and a hemodynamic standpoint. -FAU - Pibarot, Philippe -AU - Pibarot P -AD - Québec Heart Institute/Laval Hospital Research Center, Laval University, - Saint-Foy, Quebec City, Quebec. philippe.pibarot@med.ulaval.ca -FAU - Dumesnil, Jean G -AU - Dumesnil JG -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -EIN - Can J Cardiol. 2009 Mar;25(3):140 -MH - Aortic Valve/pathology/*physiology/physiopathology -MH - Aortic Valve Stenosis/*diagnosis/physiopathology/*therapy -MH - *Hemodynamics -MH - Humans -MH - Hypertension/*physiopathology -MH - Stroke Volume -MH - Ultrasonography, Doppler -MH - Ventricular Function, Left -PMC - PMC2794462 -EDAT- 2007/12/06 09:00 -MHDA- 2009/07/10 09:00 -PMCR- 2008/10/01 -CRDT- 2007/12/06 09:00 -PHST- 2007/12/06 09:00 [pubmed] -PHST- 2009/07/10 09:00 [medline] -PHST- 2007/12/06 09:00 [entrez] -PHST- 2008/10/01 00:00 [pmc-release] -AID - S0828-282X(07)71009-7 [pii] -AID - cjc23040b [pii] -AID - 10.1016/s0828-282x(07)71009-7 [doi] -PST - ppublish -SO - Can J Cardiol. 2007 Oct;23 Suppl B(Suppl B):40B-47B. doi: - 10.1016/s0828-282x(07)71009-7. - -PMID- 21303843 -OWN - NLM -STAT- MEDLINE -DCOM- 20110527 -LR - 20110209 -IS - 1753-9455 (Electronic) -IS - 1753-9447 (Linking) -VI - 4 -IP - 4 -DP - 2010 Aug -TI - Antiplatelet therapy and vascular disease: an update. -PG - 249-75 -LID - 10.1177/1753944710375780 [doi] -AB - Atherosclerosis is a diffuse, systemic disorder of the large and medium-sized - arterial vessels, affecting the coronary, cerebral and peripheral circulation. - Chronic inflammatory processes are the central pathophysiological mechanism - largely driven by lipid accumulation, and provide the substrate for occlusive - thrombus formation. The clinical sequelae of acute arterial thrombosis, heart - attack and stroke, are the most common causes of morbidity and mortality in the - industrialized world. Such acute events are characterized by rupture or erosion - of the atherosclerotic plaque leading to acute thrombosis. The atherosclerotic - process and associated thrombotic complications are collectively termed - atherothrombosis. The platelet is a pivotal mediator of various endothelial, - immune, thrombotic and inflammatory responses and therefore a key player in the - initiation and progression of atherothrombosis. A robust evidence base supports - the clear clinical benefits of antiplatelet agents in the primary and secondary - therapy of atherothrombotic disorders. Percutaneous coronary and peripheral - interventions have an established central role in the management of - atherothrombotic disease and demand a greater understanding of platelet biology. - In this article, we provide a clinically orientated overview of the - pathophysiology of arterial thrombosis and the evidence supporting the use of the - various established antiplatelet therapies, and discuss new and future agents. -FAU - Buch, Mamta H -AU - Buch MH -AD - Cedars-Sinai Medical Center, Cardiovascular Intervention Center, 8631 W Third - Street, Room 415E, Los Angeles, CA 90048, USA. mamta.h.buch@gmail.com -FAU - Prendergast, Bernard D -AU - Prendergast BD -FAU - Storey, Robert F -AU - Storey RF -LA - eng -GR - Department of Health/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Ther Adv Cardiovasc Dis -JT - Therapeutic advances in cardiovascular disease -JID - 101316343 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Animals -MH - Atherosclerosis/blood/complications/*drug therapy/physiopathology -MH - Blood Platelets/*drug effects -MH - Evidence-Based Medicine -MH - Hemorrhage/chemically induced -MH - Humans -MH - Platelet Aggregation Inhibitors/adverse effects/*therapeutic use -MH - Thrombosis/blood/*drug therapy/etiology/physiopathology -MH - Treatment Outcome -EDAT- 2011/02/10 06:00 -MHDA- 2011/05/28 06:00 -CRDT- 2011/02/10 06:00 -PHST- 2011/02/10 06:00 [entrez] -PHST- 2011/02/10 06:00 [pubmed] -PHST- 2011/05/28 06:00 [medline] -AID - 4/4/249 [pii] -AID - 10.1177/1753944710375780 [doi] -PST - ppublish -SO - Ther Adv Cardiovasc Dis. 2010 Aug;4(4):249-75. doi: 10.1177/1753944710375780. - -PMID- 20842742 -OWN - NLM -STAT- MEDLINE -DCOM- 20110602 -LR - 20211020 -IS - 1932-8737 (Electronic) -IS - 0160-9289 (Print) -IS - 0160-9289 (Linking) -VI - 33 -IP - 9 -DP - 2010 Sep -TI - The effect of aldosterone antagonists for ventricular arrhythmia: a - meta-analysis. -PG - 572-7 -LID - 10.1002/clc.20762 [doi] -AB - BACKGROUND: Sudden cardiac death (SCD) from cardiac arrest, one of the most - common types of cardiac-related death, is most often triggered by ventricular - arrhythmia (VA). It has been reported that aldosterone antagonists (AAs) have the - benefit of reducing SCD in patients with heart failure (HF). It also has been - indicated in animal experiments and clinical trials that AAs may have an - antiarrhythmic effect. HYPOTHESIS: AAs have an effect on VA in patients with HF - or coronary artery disease. METHODS: We searched the Cochrane Central Register of - Controlled Trials, PubMed, Current Controlled Trials, and the National Research - Register, and identified randomized controlled trials on the effect of AAs on VA. - RESULTS: All together, 7 trials with a total of 8635 patients were identified and - extracted. AAs reduced the risk of SCD in patients with HF by 21% (relative risk - [RR]: 0.79, 95% confidence interval [CI]: 0.67-0.93). AAs significantly reduced - the episodes of ventricular premature complexes (mean difference 705 ± 646 - episodes per 24 hours). Risk of ventricular tachycardia was reduced by 72% (RR: - 0.28, 95% CI: 0.10-0.77). CONCLUSIONS: The additional administration of AAs in - patients with HF or coronary artery disease shows a benefit in reducing the risk - of SCD and may also be effective for reducing episodes of ventricular premature - complexes and ventricular tachycardia. -CI - Copyright © 2010 Wiley Periodicals, Inc. -FAU - Wei, Jiafu -AU - Wei J -AD - Cardiology Department, West China Second University Hospital, Sichuan University, - Sichuan, China. -FAU - Ni, Juan -AU - Ni J -FAU - Huang, Dejia -AU - Huang D -FAU - Chen, Mao -AU - Chen M -FAU - Yan, Shaodi -AU - Yan S -FAU - Peng, Yong -AU - Peng Y -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Clin Cardiol -JT - Clinical cardiology -JID - 7903272 -RN - 0 (Diuretics) -RN - 0 (Mineralocorticoid Receptor Antagonists) -RN - 27O7W4T232 (Spironolactone) -RN - 6995V82D0B (Eplerenone) -SB - IM -MH - Confidence Intervals -MH - Death, Sudden, Cardiac/prevention & control -MH - Diuretics/*therapeutic use -MH - Eplerenone -MH - Humans -MH - Mineralocorticoid Receptor Antagonists/*therapeutic use -MH - Risk -MH - Spironolactone/analogs & derivatives/*therapeutic use -PMC - PMC6653357 -EDAT- 2010/09/16 06:00 -MHDA- 2011/06/03 06:00 -PMCR- 2010/09/09 -CRDT- 2010/09/16 06:00 -PHST- 2010/09/16 06:00 [entrez] -PHST- 2010/09/16 06:00 [pubmed] -PHST- 2011/06/03 06:00 [medline] -PHST- 2010/09/09 00:00 [pmc-release] -AID - CLC20762 [pii] -AID - 10.1002/clc.20762 [doi] -PST - ppublish -SO - Clin Cardiol. 2010 Sep;33(9):572-7. doi: 10.1002/clc.20762. - -PMID- 21383339 -OWN - NLM -STAT- MEDLINE -DCOM- 20120803 -LR - 20131121 -IS - 1552-4604 (Electronic) -IS - 0091-2700 (Linking) -VI - 52 -IP - 3 -DP - 2012 Mar -TI - Efficacy of metabolic modulators in ischemic heart disease: an overview. -PG - 292-305 -LID - 10.1177/0091270010396042 [doi] -AB - Myocardial ischemia results in a decrease in oxygen supply to the heart, leading - to cardiac dysfunction. Present therapeutic strategies for treating myocardial - ischemia or infarction focus on maintaining coronary artery patency by either - fibrinolysis or primary percutaneous intervention. Although these approaches have - dramatically improved the prognosis in patients with angina pectoris and - myocardial infarction, the complication of myocardial ischemia remains a major - cause of mortality and morbidity worldwide. A novel approach that entails - improving and optimizing cardiac energy metabolism of the ischemic myocardium by - pharmacologically manipulating different metabolic pathways in the heart holds - promise in limiting myocardial damage. Metabolic support of the ischemic - myocardium is aimed at increasing glycolysis and residual oxidative - phosphorylation of glucose along with decreasing fatty acid oxidation. This - review discusses the various metabolic modulators, both conventional and new, - along with documented evidence in both acute and chronic angina. -FAU - Kalra, Bhupinder S -AU - Kalra BS -AD - Department of Pharmacology, Maulana Azad Medical College, Bahadur shah zafar - marg, Delhi 110002, India. drbskalra@yahoo.co.in -FAU - Roy, Vandana -AU - Roy V -LA - eng -PT - Journal Article -PT - Review -DEP - 20110307 -PL - England -TA - J Clin Pharmacol -JT - Journal of clinical pharmacology -JID - 0366372 -RN - 0 (Cardiovascular Agents) -RN - 0 (Enzyme Inhibitors) -RN - IY9XDZ35W2 (Glucose) -SB - IM -MH - Cardiovascular Agents/*therapeutic use -MH - Enzyme Inhibitors/*pharmacology -MH - Glucose/*metabolism -MH - Glycolysis/*drug effects -MH - Humans -MH - Myocardial Ischemia/*drug therapy -EDAT- 2011/03/09 06:00 -MHDA- 2012/08/04 06:00 -CRDT- 2011/03/09 06:00 -PHST- 2011/03/09 06:00 [entrez] -PHST- 2011/03/09 06:00 [pubmed] -PHST- 2012/08/04 06:00 [medline] -AID - 0091270010396042 [pii] -AID - 10.1177/0091270010396042 [doi] -PST - ppublish -SO - J Clin Pharmacol. 2012 Mar;52(3):292-305. doi: 10.1177/0091270010396042. Epub - 2011 Mar 7. - -PMID- 19821306 -OWN - NLM -STAT- MEDLINE -DCOM- 20100127 -LR - 20250623 -IS - 1469-493X (Electronic) -IS - 1361-6137 (Linking) -IP - 4 -DP - 2009 Oct 7 -TI - Artichoke leaf extract for treating hypercholesterolaemia. -PG - CD003335 -LID - 10.1002/14651858.CD003335.pub2 [doi] -AB - BACKGROUND: Hypercholesterolaemia is directly associated with an increased risk - for coronary heart disease and other sequelae of atherosclerosis. Artichoke leaf - extract (ALE) has been implicated in lowering cholesterol levels. Whether ALE is - truly effective for this indication, however, is still a matter of debate. - OBJECTIVES: To assess the evidence of ALE versus placebo or reference medication - for treating hypercholesterolaemia defined as mean total cholesterol levels of at - least 5.17 mmol/L (200 mg/dL). SEARCH STRATEGY: We searched the Cochrane Central - Register of Controlled Trials 2008 Issue 2, MEDLINE, EMBASE, AMED and CINAHL from - their respective inception until June 2008; CISCOM until June 2001. Reference - lists of articles were checked. Manufacturers of preparations containing - artichoke extract and experts on the subject were contacted. SELECTION CRITERIA: - Randomised controlled trials (RCTs) of ALE mono-preparations compared with - placebo or reference medication for patients with hypercholesterolaemia were - included. Trials assessing ALE as one of several active components in a - combination preparation or as a part of a combination treatment were excluded. - DATA COLLECTION AND ANALYSIS: Data were extracted systematically and - methodological quality was evaluated using a standard scoring system and the - Cochrane risk of bias assessment. The screening of studies, selection, data - extraction and assessment of methodological quality were performed independently - by two reviewers. Disagreements in the evaluation of individual trials were - resolved through discussion. MAIN RESULTS: Three RCTs (262 participants) met all - inclusion criteria. In one trial the total cholesterol level in participants - receiving ALE decreased by 4.2% from 7.16 (0.62) mmol/L to 6.86 (0.68) mmol/L - after 12 weeks and increased from 6.90 (0.49) mmol/L to 7.04 (0.61) mmol/L in - patients receiving placebo, the total difference being statistically significant - (P = 0.025). In a further trial ALE reduced total cholesterol levels by 18.5% - from 7.74 mmol/L to 6.31 mmol/L after 42 +/- 3 days of treatment whereas the - placebo reduced cholesterol by 8.6% from 7.69 mmol/L to 7.03 mmol/L (P = - 0.00001). Another trial did state that ALE significantly reduced blood - cholesterol compared with placebo in a sub-group of patients with baseline total - cholesterol levels of more than 230 mg/dL (P < 0.05). Trial reports indicate - mild, transient and infrequent adverse events. AUTHORS' CONCLUSIONS: Some data - from clinical trials assessing ALE for treating hypercholesterolaemia exist. - There is an indication that ALE has potential in lowering cholesterol levels, the - evidence is, however, as yet not convincing. The limited data on safety suggest - only mild, transient and infrequent adverse events with the short term use of - ALE. -FAU - Wider, Barbara -AU - Wider B -AD - Complementary Medicine, Peninsula Medical School, Universities of Exeter and - Plymouth, 25 Victoria Park Road, Exeter, UK, EX2 4NT. -FAU - Pittler, Max H -AU - Pittler MH -FAU - Thompson-Coon, Joanna -AU - Thompson-Coon J -FAU - Ernst, Edzard -AU - Ernst E -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -DEP - 20091007 -PL - England -TA - Cochrane Database Syst Rev -JT - The Cochrane database of systematic reviews -JID - 100909747 -RN - 0 (Plant Extracts) -SB - IM -UOF - Cochrane Database Syst Rev. 2002;(3):CD003335. doi: 10.1002/14651858.CD003335. - PMID: 12137691 -UIN - Cochrane Database Syst Rev. 2013 Mar 28;(3):CD003335. doi: - 10.1002/14651858.CD003335.pub3. PMID: 23543518 -MH - Cynara scolymus/*chemistry -MH - Humans -MH - Hypercholesterolemia/*drug therapy -MH - *Phytotherapy -MH - Plant Extracts/therapeutic use -MH - Plant Leaves/*chemistry -MH - Randomized Controlled Trials as Topic -RF - 85 -EDAT- 2009/10/13 06:00 -MHDA- 2010/01/28 06:00 -CRDT- 2009/10/13 06:00 -PHST- 2009/10/13 06:00 [entrez] -PHST- 2009/10/13 06:00 [pubmed] -PHST- 2010/01/28 06:00 [medline] -AID - 10.1002/14651858.CD003335.pub2 [doi] -PST - epublish -SO - Cochrane Database Syst Rev. 2009 Oct 7;(4):CD003335. doi: - 10.1002/14651858.CD003335.pub2. - -PMID- 23692935 -OWN - NLM -STAT- MEDLINE -DCOM- 20140320 -LR - 20130522 -IS - 1558-3481 (Electronic) -IS - 0899-5885 (Linking) -VI - 25 -IP - 2 -DP - 2013 Jun -TI - Bee and wasp stings: reactions and anaphylaxis. -PG - 151-64 -LID - S0899-5885(13)00004-X [pii] -LID - 10.1016/j.ccell.2013.02.002 [doi] -AB - This article provides a brief introduction to the history of anaphylaxis and the - order Hymenoptera, which is responsible for most reported sting-induced allergic - reactions. The anatomic similarities and differences as well as inhabited - similarities and differences between bees and wasps are discussed. The various - types of allergic reactions and their manifestations are described. Treatment - regimens ranging from home therapies and over-the-counter medications to - prescription medications and emergency treatments are introduced. Education, - avoidance, and venom-specific immunotherapy are discussed. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Smallheer, Benjamin A -AU - Smallheer BA -AD - Vanderbilt University School of Nursing, Nashville, TN 37240, USA. - benjamin.a.smallheer@vanderbilt.edu -LA - eng -PT - Journal Article -PT - Review -DEP - 20130306 -PL - United States -TA - Crit Care Nurs Clin North Am -JT - Critical care nursing clinics of North America -JID - 8912620 -MH - Anaphylaxis -MH - Animals -MH - *Bees/immunology -MH - Coronary Vasospasm/immunology -MH - Humans -MH - Insect Bites and Stings/*immunology -MH - Kidney/immunology -MH - Lung/immunology -MH - *Wasps/immunology -EDAT- 2013/05/23 06:00 -MHDA- 2014/03/22 06:00 -CRDT- 2013/05/23 06:00 -PHST- 2013/05/23 06:00 [entrez] -PHST- 2013/05/23 06:00 [pubmed] -PHST- 2014/03/22 06:00 [medline] -AID - S0899-5885(13)00004-X [pii] -AID - 10.1016/j.ccell.2013.02.002 [doi] -PST - ppublish -SO - Crit Care Nurs Clin North Am. 2013 Jun;25(2):151-64. doi: - 10.1016/j.ccell.2013.02.002. Epub 2013 Mar 6. - -PMID- 23078727 -OWN - NLM -STAT- MEDLINE -DCOM- 20130410 -LR - 20220330 -IS - 1876-7605 (Electronic) -IS - 1936-8798 (Linking) -VI - 5 -IP - 10 -DP - 2012 Oct -TI - Paclitaxel drug-coated balloons: a review of current status and emerging - applications in native coronary artery de novo lesions. -PG - 1001-12 -LID - S1936-8798(12)00769-8 [pii] -LID - 10.1016/j.jcin.2012.08.005 [doi] -AB - The paclitaxel drug-coated balloon (DCB) is an emerging device in percutaneous - coronary intervention, which has shown promising results by means of a - high-concentration, rapid local release of an antirestenotic drug without the use - of a durable polymer or metal scaffold. DCB have already proven effective in - clinical trials for the treatment of in-stent restenosis. Its coronary - applications may potentially be widened to a host of complex coronary de novo - lesion subsets, such as small-caliber vessels, diabetes, and diffuse lesions, - where the use of stents may be hampered by suboptimal results. Recently, this - technology has rapidly evolved with newer studies added to assess the value of - DCB in coronary applications other than in-stent restenosis. We present a review - of the role of DCB in de novo coronary lesions based on this latest clinical - evidence. -CI - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Loh, Joshua P -AU - Loh JP -AD - Department of Interventional Cardiology, MedStar Washington Hospital Center, - Washington, DC, USA. -FAU - Waksman, Ron -AU - Waksman R -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - JACC Cardiovasc Interv -JT - JACC. Cardiovascular interventions -JID - 101467004 -RN - 0 (Antineoplastic Agents, Phytogenic) -RN - P88XT4IS4D (Paclitaxel) -SB - IM -MH - *Angioplasty, Balloon -MH - Antineoplastic Agents, Phytogenic/administration & dosage/*therapeutic use -MH - Coronary Restenosis/*prevention & control -MH - Coronary Vessels/*pathology -MH - Diabetes Mellitus -MH - *Drug-Eluting Stents -MH - Humans -MH - Paclitaxel/administration & dosage/*therapeutic use -EDAT- 2012/10/20 06:00 -MHDA- 2013/04/11 06:00 -CRDT- 2012/10/20 06:00 -PHST- 2012/06/07 00:00 [received] -PHST- 2012/08/24 00:00 [revised] -PHST- 2012/08/29 00:00 [accepted] -PHST- 2012/10/20 06:00 [entrez] -PHST- 2012/10/20 06:00 [pubmed] -PHST- 2013/04/11 06:00 [medline] -AID - S1936-8798(12)00769-8 [pii] -AID - 10.1016/j.jcin.2012.08.005 [doi] -PST - ppublish -SO - JACC Cardiovasc Interv. 2012 Oct;5(10):1001-12. doi: 10.1016/j.jcin.2012.08.005. - -PMID- 22920490 -OWN - NLM -STAT- MEDLINE -DCOM- 20130510 -LR - 20211021 -IS - 1875-6557 (Electronic) -IS - 1573-403X (Print) -IS - 1573-403X (Linking) -VI - 8 -IP - 3 -DP - 2012 Aug -TI - Embolic protection devices in saphenous vein graft and native vessel percutaneous - intervention: a review. -PG - 192-9 -AB - The clinical benefit of percutaneous intervention (PCI) depends on both - angiographic success at the site of intervention as well as the restoration of - adequate microvascular perfusion. Saphenous vein graft intervention is commonly - associated with evidence of distal plaque embolization, which is correlated with - worse clinical outcomes. Despite successful epicardial intervention in the acute - MI patient treated with primary PCI, distal tissue perfusion may still be absent - in up to 25% of cases [1-3]. Multiple devices and pharmacologic regimens have - been developed and refined in an attempt to protect the microvascular circulation - during both saphenous vein graft intervention and primary PCI in the acute MI - setting. We will review the evidence for various techniques for embolic - protection of the distal myocardium during saphenous vein graft PCI and primary - PCI in the native vessel. -FAU - Sturm, Eron -AU - Sturm E -AD - Department of Cardiovascular Medicine, Hahnemann University Hospital, - Philadelphia, PA, USA. eron.sturm@gmail.com -FAU - Goldberg, David -AU - Goldberg D -FAU - Goldberg, Sheldon -AU - Goldberg S -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Cardiol Rev -JT - Current cardiology reviews -JID - 101261935 -SB - IM -MH - Balloon Occlusion/instrumentation -MH - Coronary Thrombosis/therapy -MH - *Embolic Protection Devices -MH - Graft Occlusion, Vascular/prevention & control -MH - Humans -MH - Myocardial Infarction/*therapy -MH - Percutaneous Coronary Intervention/*instrumentation/methods -MH - Prosthesis Design -MH - Risk Factors -MH - Saphenous Vein/*transplantation -MH - Thrombectomy/instrumentation/methods -PMC - PMC3465823 -EDAT- 2012/08/28 06:00 -MHDA- 2013/05/11 06:00 -PMCR- 2013/08/01 -CRDT- 2012/08/28 06:00 -PHST- 2012/03/16 00:00 [received] -PHST- 2012/03/30 00:00 [revised] -PHST- 2012/04/09 00:00 [accepted] -PHST- 2012/08/28 06:00 [entrez] -PHST- 2012/08/28 06:00 [pubmed] -PHST- 2013/05/11 06:00 [medline] -PHST- 2013/08/01 00:00 [pmc-release] -AID - CCR-EPUB-20120817-17 [pii] -AID - CCR-8-192 [pii] -AID - 10.2174/157340312803217201 [doi] -PST - ppublish -SO - Curr Cardiol Rev. 2012 Aug;8(3):192-9. doi: 10.2174/157340312803217201. - -PMID- 22433655 -OWN - NLM -STAT- MEDLINE -DCOM- 20121106 -LR - 20120321 -IS - 1873-2615 (Electronic) -IS - 1050-1738 (Linking) -VI - 20 -IP - 8 -DP - 2010 Nov -TI - Myeloperoxidase may help to differentiate coronary plaque erosion from plaque - rupture in patients with acute coronary syndromes. -PG - 276-81 -LID - 10.1016/j.tcm.2011.12.008 [doi] -AB - Coronary thrombosis is the most frequent final event leading to an acute coronary - syndrome. In approximately two-thirds of cases, the thrombus overlies a ruptured - plaque, whereas in one-third of cases it overlies an intact plaque with - superficial endothelial erosion, a finding showed initially by histopathological - postmortem studies and more recently confirmed by in vivo optical coherence - tomography imaging. Interestingly, recent observations suggest that mechanisms - leading to plaque rupture or erosion are different. In fact, in a recent study, - we showed that myeloperoxidase levels in peripheral blood and expression within - thrombi overlying the culprit plaque are much higher in patients with plaque - erosion than in those with plaque rupture. These observations suggest that innate - immunity activation is likely to play a key role, in particular, in plaque - erosion and might become a therapeutic target in this subset of patients. -CI - Copyright © 2010 Elsevier Inc. All rights reserved. -FAU - Niccoli, Giampaolo -AU - Niccoli G -AD - Institute of Cardiology, Catholic University of the Sacred Heart, 00168 Rome, - Italy. -FAU - Dato, Ilaria -AU - Dato I -FAU - Crea, Filippo -AU - Crea F -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Trends Cardiovasc Med -JT - Trends in cardiovascular medicine -JID - 9108337 -RN - EC 1.11.1.7 (Peroxidase) -SB - IM -MH - Acute Coronary Syndrome/*pathology -MH - Coronary Thrombosis/*pathology -MH - Coronary Vessels/chemistry/*pathology -MH - Diagnosis, Differential -MH - Humans -MH - Peroxidase/*analysis/blood/physiology -MH - Plaque, Atherosclerotic/*chemistry/pathology/physiopathology -MH - Rupture, Spontaneous/pathology -EDAT- 2010/11/01 00:00 -MHDA- 2012/11/07 06:00 -CRDT- 2012/03/22 06:00 -PHST- 2012/03/22 06:00 [entrez] -PHST- 2010/11/01 00:00 [pubmed] -PHST- 2012/11/07 06:00 [medline] -AID - S1050-1738(11)00107-1 [pii] -AID - 10.1016/j.tcm.2011.12.008 [doi] -PST - ppublish -SO - Trends Cardiovasc Med. 2010 Nov;20(8):276-81. doi: 10.1016/j.tcm.2011.12.008. - -PMID- 18523327 -OWN - NLM -STAT- MEDLINE -DCOM- 20080926 -LR - 20101118 -IS - 1557-2501 (Electronic) -IS - 1042-3931 (Linking) -VI - 20 -IP - 6 -DP - 2008 Jun -TI - Novel use of twin-pass catheter in successful recanalization of a chronic - coronary total occlusion. -PG - 309-11 -AB - One of the most difficult challenges in interventional cardiology has been in - finding the approach to treat chronic total occlusions (CTOs). Here we present a - case of recanalization of an angulated, calcified CTO. The lesion presented - difficulty due to the lack of guidewire support to facilitate crossing of the - CTO. In our case, an uncommon approach using a dual-lumen catheter (Twin-Pass) to - support and direct a guidewire was attempted. This resulted in a successful - percutaneous revascularization. -FAU - Arif, Imran -AU - Arif I -AD - University of Cincinnati School of Medicine, Cardiovascular Diseases, 231 Albert - Sabin Way, ML 0542, PO Box 670542, Cincinnati, OH 45267, USA. - arifin@ucmail.uc.edu -FAU - Callihan, Richard -AU - Callihan R -FAU - Helmy, Tarek -AU - Helmy T -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - J Invasive Cardiol -JT - The Journal of invasive cardiology -JID - 8917477 -SB - IM -MH - Acute Coronary Syndrome/*therapy -MH - Aged -MH - Angioplasty, Balloon, Coronary/adverse effects/*instrumentation/methods -MH - Calcinosis/*therapy -MH - Coronary Occlusion/*therapy -MH - Humans -MH - Male -RF - 16 -EDAT- 2008/06/05 09:00 -MHDA- 2008/09/27 09:00 -CRDT- 2008/06/05 09:00 -PHST- 2008/06/05 09:00 [pubmed] -PHST- 2008/09/27 09:00 [medline] -PHST- 2008/06/05 09:00 [entrez] -PST - ppublish -SO - J Invasive Cardiol. 2008 Jun;20(6):309-11. - -PMID- 18410596 -OWN - NLM -STAT- MEDLINE -DCOM- 20080729 -LR - 20220408 -IS - 1365-2796 (Electronic) -IS - 0954-6820 (Linking) -VI - 263 -IP - 5 -DP - 2008 May -TI - Role of microparticles in atherothrombosis. -PG - 528-37 -LID - 10.1111/j.1365-2796.2008.01957.x [doi] -AB - Cell activation or apoptosis leads to plasma membrane blebbing and microparticle - (MP) release in the extracellular space. MPs are submicron membrane vesicles - which express a panel of phospholipids and proteins specific of the cells they - are derived from. Exposure of negatively charged phospholipids and tissue factor - confers a procoagulant potential to MPs. MPs accumulate in the lipid core of the - atherosclertotic plaque and is a major determinant of its thrombogenecity. - Elevation of plasma MPs levels, particularly those of endothelial origin, - reflects cellular injury and is considered now as a surrogate marker of vascular - dysfunction. Thus, MPs can be seen as triggers of a vicious circle for they - promote prothrombogenic and pro-inflammatory responses as well as cellular - dysfunction within the vascular compartment. A better knowledge of MP composition - and biological effects as well as the mechanisms leading to their clearance will - probably open new therapeutic approaches in the treatment of atherothrombosis. -FAU - Leroyer, A S -AU - Leroyer AS -AD - Institut National de la Santé et de la Recherche Médicale (Unit 689), - Cardiovascular Research Institute Inserm, Paris, France. -FAU - Tedgui, A -AU - Tedgui A -FAU - Boulanger, C M -AU - Boulanger CM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - J Intern Med -JT - Journal of internal medicine -JID - 8904841 -SB - IM -MH - Apoptosis -MH - Atherosclerosis/blood/*pathology/physiopathology -MH - Cell Membrane/*ultrastructure -MH - Coronary Thrombosis/*pathology -MH - Endothelial Cells/*ultrastructure -MH - Erythrocytes/ultrastructure -MH - Female -MH - Humans -MH - Male -MH - Myocytes, Smooth Muscle/ultrastructure -RF - 89 -EDAT- 2008/04/16 09:00 -MHDA- 2008/07/30 09:00 -CRDT- 2008/04/16 09:00 -PHST- 2008/04/16 09:00 [pubmed] -PHST- 2008/07/30 09:00 [medline] -PHST- 2008/04/16 09:00 [entrez] -AID - JIM1957 [pii] -AID - 10.1111/j.1365-2796.2008.01957.x [doi] -PST - ppublish -SO - J Intern Med. 2008 May;263(5):528-37. doi: 10.1111/j.1365-2796.2008.01957.x. - -PMID- 18758181 -OWN - NLM -STAT- MEDLINE -DCOM- 20090603 -LR - 20220316 -IS - 1421-9751 (Electronic) -IS - 0008-6312 (Linking) -VI - 112 -IP - 4 -DP - 2009 -TI - Ischemic mitral regurgitation: a complex multifaceted disease. -PG - 244-59 -LID - 10.1159/000151693 [doi] -AB - Ischemic mitral regurgitation (MR) is a complex multifactorial disease that - involves global and regional left ventricular remodeling as well as dysfunction - and distortion of the components of the mitral valve including the chordae, - annulus and leaflets. This is a frequent (13-59%) complication of myocardial - infarction, which is associated with a poor prognosis. The suboptimal results - obtained with the most commonly used surgical strategy, that is, restrictive - annuloplasty combined with coronary artery bypass graft, emphasize the need to - develop alternative or concomitant surgical techniques that directly target the - causal mechanisms of the disease. A comprehensive assessment of mitral valve - configuration and left ventricular geometry and function prior to surgery as well - as an accurate quantification of MR severity at rest and during exercise may help - improve patient risk stratification and better individualize the surgical - strategy based on the patient's specific characteristics. The purpose of this - review is to summarize the current state of knowledge with regard to the - definition, prevalence, mechanisms, outcome and treatment of ischemic MR. -CI - Copyright 2008 S. Karger AG, Basel. -FAU - Magne, Julien -AU - Magne J -AD - Laval Hospital Research Center/Québec Heart Institute, Faculty of Medicine, Laval - University, Québec, QC, Canada. -FAU - Sénéchal, Mario -AU - Sénéchal M -FAU - Dumesnil, Jean G -AU - Dumesnil JG -FAU - Pibarot, Philippe -AU - Pibarot P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080830 -PL - Switzerland -TA - Cardiology -JT - Cardiology -JID - 1266406 -SB - IM -CIN - Cardiology. 2009;112(4):243. doi: 10.1159/000151692. PMID: 18758180 -MH - Cardiac Surgical Procedures/methods -MH - *Coronary Artery Bypass -MH - Humans -MH - Mitral Valve Insufficiency/diagnosis/epidemiology/etiology/*surgery -MH - Myocardial Infarction/complications -MH - Myocardial Ischemia/*complications/surgery -MH - Prevalence -MH - Quebec/epidemiology -MH - Risk Assessment -MH - Stroke Volume -MH - Treatment Outcome -RF - 107 -EDAT- 2008/09/02 09:00 -MHDA- 2009/06/06 09:00 -CRDT- 2008/09/02 09:00 -PHST- 2008/02/14 00:00 [received] -PHST- 2008/04/30 00:00 [accepted] -PHST- 2008/09/02 09:00 [pubmed] -PHST- 2009/06/06 09:00 [medline] -PHST- 2008/09/02 09:00 [entrez] -AID - 000151693 [pii] -AID - 10.1159/000151693 [doi] -PST - ppublish -SO - Cardiology. 2009;112(4):244-59. doi: 10.1159/000151693. Epub 2008 Aug 30. - -PMID- 19213064 -OWN - NLM -STAT- MEDLINE -DCOM- 20090917 -LR - 20181201 -IS - 1522-726X (Electronic) -IS - 1522-1946 (Linking) -VI - 74 Suppl 1 -DP - 2009 Jul 1 -TI - Antiplatelet therapy after endovascular intervention: does combination therapy - really work and what is the optimum duration of therapy? -PG - S7-S11 -LID - 10.1002/ccd.21996 [doi] -AB - The number of patients undergoing peripheral interventions has increased in - recent years, highlighting the need for a safe and effective protective - antithrombotic therapy. Platelet inhibition following coronary intervention is - associated with a significantly reduced risk of graft occlusion, and has been - acknowledged to be safe and effective in patients with peripheral arterial - disease. Monotherapy with either aspirin or clopidogrel, reduces the rate of - stroke, myocardial infarction, and cardiovascular death in patients suffering - from peripheral arterial disease. Limited data from clinical trials investigating - combination therapy of aspirin with ticlopidine or clopidogrel in patients - undergoing endovascular interventions, have suggested the potential for a - reduction in cardiovascular events. Nevertheless, the optimal duration of - postintervention antiplatelet therapy remains to be defined. -CI - (c) 2009 Wiley-Liss, Inc. -FAU - Milani, Richard V -AU - Milani RV -AD - Department of Cardiology, Ochsner Heart and Vascular Institute, Ochsner Clinic - Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA. - rmilani@ochsner.org -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Catheter Cardiovasc Interv -JT - Catheterization and cardiovascular interventions : official journal of the - Society for Cardiac Angiography & Interventions -JID - 100884139 -RN - 0 (Platelet Aggregation Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Angioplasty, Balloon, Coronary/adverse effects -MH - Aspirin/therapeutic use -MH - Blood Vessel Prosthesis Implantation/adverse effects -MH - Cardiovascular Diseases/complications/*drug therapy/physiopathology -MH - Clopidogrel -MH - Drug Administration Schedule -MH - Drug Therapy, Combination -MH - Evidence-Based Medicine -MH - Graft Occlusion, Vascular/etiology/prevention & control -MH - Humans -MH - Myocardial Infarction/etiology/prevention & control -MH - Peripheral Vascular Diseases/complications/*drug therapy/physiopathology/surgery -MH - Platelet Aggregation Inhibitors/*administration & dosage -MH - Thrombosis/etiology/physiopathology/*prevention & control -MH - Ticlopidine/analogs & derivatives/therapeutic use -MH - Time Factors -MH - Treatment Outcome -MH - Vascular Patency -RF - 22 -EDAT- 2009/02/13 09:00 -MHDA- 2009/09/18 06:00 -CRDT- 2009/02/13 09:00 -PHST- 2009/02/13 09:00 [entrez] -PHST- 2009/02/13 09:00 [pubmed] -PHST- 2009/09/18 06:00 [medline] -AID - 10.1002/ccd.21996 [doi] -PST - ppublish -SO - Catheter Cardiovasc Interv. 2009 Jul 1;74 Suppl 1:S7-S11. doi: 10.1002/ccd.21996. - -PMID- 22864856 -OWN - NLM -STAT- MEDLINE -DCOM- 20130430 -LR - 20211021 -IS - 1546-9549 (Electronic) -IS - 1546-9530 (Print) -IS - 1546-9530 (Linking) -VI - 9 -IP - 4 -DP - 2012 Dec -TI - Gender differences in the pathophysiology, clinical presentation, and outcomes of - ischemic heart failure. -PG - 267-76 -LID - 10.1007/s11897-012-0107-7 [doi] -AB - Despite advances in the treatment of acute myocardial infarction (MI), heart - failure (HF) remains a frequent acute and long-term outcome of ischemic heart - disease (IHD). In response to acute coronary ischemia, women are relatively - protected from apoptosis, and experience less adverse cardiac remodeling than - men, frequently resulting in preservation of left ventricular size and ejection - fraction. Despite these advantages, women are at increased risk for HF- - complicating acute MI when compared with men. However, women with HF retain a - survival advantage over men with HF, including a decreased risk of sudden death. - Sex-specific treatment of HF has been hindered by historical under-representation - of women in clinical trials, though recent work has suggested that women may have - a differential response to some therapies such as cardiac resynchronization. This - review highlights the sex differences in the pathophysiology, clinical - presentation and outcomes of ischemic heart failure and discusses key areas - worthy of further investigation. -FAU - Dunlay, Shannon M -AU - Dunlay SM -AD - Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, - Rochester, MN 55905, USA. -FAU - Roger, Véronique L -AU - Roger VL -LA - eng -GR - R01 HL072435/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Review -PL - United States -TA - Curr Heart Fail Rep -JT - Current heart failure reports -JID - 101196487 -SB - IM -MH - Female -MH - Heart Failure/epidemiology/etiology/*physiopathology/therapy -MH - Humans -MH - Male -MH - Myocardial Infarction/complications -MH - Prognosis -MH - Risk Factors -MH - *Sex Characteristics -MH - Treatment Outcome -MH - Ventricular Remodeling/physiology -PMC - PMC3736841 -MID - NIHMS398700 -EDAT- 2012/08/07 06:00 -MHDA- 2013/05/01 06:00 -PMCR- 2013/12/01 -CRDT- 2012/08/07 06:00 -PHST- 2012/08/07 06:00 [entrez] -PHST- 2012/08/07 06:00 [pubmed] -PHST- 2013/05/01 06:00 [medline] -PHST- 2013/12/01 00:00 [pmc-release] -AID - 10.1007/s11897-012-0107-7 [doi] -PST - ppublish -SO - Curr Heart Fail Rep. 2012 Dec;9(4):267-76. doi: 10.1007/s11897-012-0107-7. - -PMID- 18612117 -OWN - NLM -STAT- MEDLINE -DCOM- 20080718 -LR - 20250529 -IS - 1538-3598 (Electronic) -IS - 0098-7484 (Print) -IS - 0098-7484 (Linking) -VI - 300 -IP - 2 -DP - 2008 Jul 9 -TI - Ankle brachial index combined with Framingham Risk Score to predict - cardiovascular events and mortality: a meta-analysis. -PG - 197-208 -LID - 10.1001/jama.300.2.197 [doi] -AB - CONTEXT: Prediction models to identify healthy individuals at high risk of - cardiovascular disease have limited accuracy. A low ankle brachial index (ABI) is - an indicator of atherosclerosis and has the potential to improve prediction. - OBJECTIVE: To determine if the ABI provides information on the risk of - cardiovascular events and mortality independently of the Framingham risk score - (FRS) and can improve risk prediction. DATA SOURCES: Relevant studies were - identified. A search of MEDLINE (1950 to February 2008) and EMBASE (1980 to - February 2008) was conducted using common text words for the term ankle brachial - index combined with text words and Medical Subject Headings to capture - prospective cohort designs. Review of reference lists and conference proceedings, - and correspondence with experts was conducted to identify additional published - and unpublished studies. STUDY SELECTION: Studies were included if participants - were derived from a general population, ABI was measured at baseline, and - individuals were followed up to detect total and cardiovascular mortality. DATA - EXTRACTION: Prespecified data on individuals in each selected study were - extracted into a combined data set and an individual participant data - meta-analysis was conducted on individuals who had no previous history of - coronary heart disease. RESULTS: Sixteen population cohort studies fulfilling the - inclusion criteria were included. During 480,325 person-years of follow-up of - 24,955 men and 23,339 women, the risk of death by ABI had a reverse J-shaped - distribution with a normal (low risk) ABI of 1.11 to 1.40. The 10-year - cardiovascular mortality in men with a low ABI (< or = 0.90) was 18.7% (95% - confidence interval [CI], 13.3%-24.1%) and with normal ABI (1.11-1.40) was 4.4% - (95% CI, 3.2%-5.7%) (hazard ratio [HR], 4.2; 95% CI, 3.3-5.4). Corresponding - mortalities in women were 12.6% (95% CI, 6.2%-19.0%) and 4.1% (95% CI, 2.2%-6.1%) - (HR, 3.5; 95% CI, 2.4-5.1). The HRs remained elevated after adjusting for FRS - (2.9 [95% CI, 2.3-3.7] for men vs 3.0 [95% CI, 2.0-4.4] for women). A low ABI (< - or = 0.90) was associated with approximately twice the 10-year total mortality, - cardiovascular mortality, and major coronary event rate compared with the overall - rate in each FRS category. Inclusion of the ABI in cardiovascular risk - stratification using the FRS would result in reclassification of the risk - category and modification of treatment recommendations in approximately 19% of - men and 36% of women. CONCLUSION: Measurement of the ABI may improve the accuracy - of cardiovascular risk prediction beyond the FRS. -CN - Ankle Brachial Index Collaboration -FAU - Fowkes, F G R -AU - Fowkes FG -FAU - Murray, G D -AU - Murray GD -FAU - Butcher, I -AU - Butcher I -FAU - Heald, C L -AU - Heald CL -FAU - Lee, R J -AU - Lee RJ -FAU - Chambless, L E -AU - Chambless LE -FAU - Folsom, A R -AU - Folsom AR -FAU - Hirsch, A T -AU - Hirsch AT -FAU - Dramaix, M -AU - Dramaix M -FAU - deBacker, G -AU - deBacker G -FAU - Wautrecht, J-C -AU - Wautrecht JC -FAU - Kornitzer, M -AU - Kornitzer M -FAU - Newman, A B -AU - Newman AB -FAU - Cushman, M -AU - Cushman M -FAU - Sutton-Tyrrell, K -AU - Sutton-Tyrrell K -FAU - Fowkes, F G R -AU - Fowkes FG -FAU - Lee, A J -AU - Lee AJ -FAU - Price, J F -AU - Price JF -FAU - d'Agostino, R B -AU - d'Agostino RB -FAU - Murabito, J M -AU - Murabito JM -FAU - Norman, P E -AU - Norman PE -FAU - Jamrozik, K -AU - Jamrozik K -FAU - Curb, J D -AU - Curb JD -FAU - Masaki, K H -AU - Masaki KH -FAU - Rodríguez, B L -AU - Rodríguez BL -FAU - Dekker, J M -AU - Dekker JM -FAU - Bouter, L M -AU - Bouter LM -FAU - Heine, R J -AU - Heine RJ -FAU - Nijpels, G -AU - Nijpels G -FAU - Stehouwer, C D A -AU - Stehouwer CD -FAU - Ferrucci, L -AU - Ferrucci L -FAU - McDermott, M M -AU - McDermott MM -FAU - Stoffers, H E -AU - Stoffers HE -FAU - Hooi, J D -AU - Hooi JD -FAU - Knottnerus, J A -AU - Knottnerus JA -FAU - Ogren, M -AU - Ogren M -FAU - Hedblad, B -AU - Hedblad B -FAU - Witteman, J C -AU - Witteman JC -FAU - Breteler, M M B -AU - Breteler MM -FAU - Hunink, M G M -AU - Hunink MG -FAU - Hofman, A -AU - Hofman A -FAU - Criqui, M H -AU - Criqui MH -FAU - Langer, R D -AU - Langer RD -FAU - Fronek, A -AU - Fronek A -FAU - Hiatt, W R -AU - Hiatt WR -FAU - Hamman, R -AU - Hamman R -FAU - Resnick, H E -AU - Resnick HE -FAU - Guralnik, J -AU - Guralnik J -FAU - McDermott, M M -AU - McDermott MM -LA - eng -GR - N01 HC025195/HC/NHLBI NIH HHS/United States -GR - N01 HC025195/HL/NHLBI NIH HHS/United States -GR - N0I-HC-25195/HC/NHLBI NIH HHS/United States -GR - ImNIH/Intramural NIH HHS/United States -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, N.I.H., Extramural -PT - Research Support, N.I.H., Intramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - JAMA -JT - JAMA -JID - 7501160 -SB - IM -MH - Adult -MH - Age Factors -MH - Aged -MH - Aged, 80 and over -MH - *Ankle -MH - Atherosclerosis/physiopathology -MH - *Blood Pressure -MH - *Brachial Artery -MH - Cardiovascular Diseases/*mortality/*physiopathology -MH - Cohort Studies -MH - Confidence Intervals -MH - Female -MH - Global Health -MH - Humans -MH - Male -MH - Middle Aged -MH - Odds Ratio -MH - Predictive Value of Tests -MH - Risk Assessment -MH - Risk Factors -MH - Severity of Illness Index -PMC - PMC2932628 -MID - NIHMS205305 -COIS- Disclosures: Several authors have received honoraria, consulting fees or research - grants from Sanofi Aventis/BMS for purposes other than this research. In addition - Dr McDermott has received consulting fees from Hutchison Technology and - educational honoraria from Otsuka Pharmaceuticals, and Dr Ogren is an employee of - AstraZeneca R + D. Otherwise, the authors have no potential conflict of interest, - including special financial interests and relationships and affiliations, - relevant to the subject of this manuscript. -EDAT- 2008/07/10 09:00 -MHDA- 2008/07/19 09:00 -PMCR- 2010/09/02 -CRDT- 2008/07/10 09:00 -PHST- 2008/07/10 09:00 [pubmed] -PHST- 2008/07/19 09:00 [medline] -PHST- 2008/07/10 09:00 [entrez] -PHST- 2010/09/02 00:00 [pmc-release] -AID - 300/2/197 [pii] -AID - 10.1001/jama.300.2.197 [doi] -PST - ppublish -SO - JAMA. 2008 Jul 9;300(2):197-208. doi: 10.1001/jama.300.2.197. - -PMID- 18344032 -OWN - NLM -STAT- MEDLINE -DCOM- 20080715 -LR - 20080317 -IS - 0340-9937 (Print) -IS - 0340-9937 (Linking) -VI - 33 -IP - 2 -DP - 2008 Mar -TI - [Cardiac magnetic resonance imaging in the diagnosis of acute coronary syndrome. - Basics and clinical value]. -PG - 129-35 -LID - 10.1007/s00059-008-3110-8 [doi] -AB - In contrast to chronic myocardial infarction, data concerning the value of - cardiac magnetic resonance imaging in patients with acute onset of chest pain are - still rare. Even in the presence of characteristic clinical parameters, cardiac - magnetic resonance imaging might provide independent evidence especially in the - absence of typical ECG alterations and prior to biomarker elevation. Besides the - ability to demonstrate wall motion abnormalities cardiac magnetic resonance - imaging gains additional potential as to the detection of myocardial edema, - microvascular obstruction (no-reflow) and myocardial necrosis. However, cardiac - magnetic resonance imaging is expensive and time-consuming, and therefore may not - be cost-effective. At present, a lack of sufficient diagnostic and prognostic - data would make cardiac magnetic resonance imaging unsuitable for routine - stratification of chest pain patients in an emergency department. -FAU - Breuckmann, Frank -AU - Breuckmann F -AD - Westdeutsches Herzzentrum Essen, Klinik für Kardiologie, Universitätsklinikum - Essen, Universität Duisburg-Essen, Essen. Frank.Breuckmann@uk-essen.de -FAU - Nassenstein, Kai -AU - Nassenstein K -FAU - Bruder, Oliver -AU - Bruder O -FAU - Buhr, Christiane -AU - Buhr C -FAU - Sievers, Burkhard -AU - Sievers B -FAU - Barkhausen, Jörg -AU - Barkhausen J -FAU - Erbel, Raimund -AU - Erbel R -FAU - Hunold, Peter -AU - Hunold P -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Kardiale Magnetresonanztomographie in der Diagnostik des akuten Koronarsyndroms. - Grundlagen und klinische Anwendungsmöglichkeiten. -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -SB - IM -MH - Acute Coronary Syndrome/*diagnosis -MH - Coronary Angiography/*methods -MH - Coronary Stenosis/diagnosis -MH - Edema/diagnosis -MH - Electrocardiography -MH - Humans -MH - Image Enhancement/*methods -MH - Image Processing, Computer-Assisted/*methods -MH - Magnetic Resonance Angiography/*methods -MH - Magnetic Resonance Imaging/*methods -MH - Myocardium/pathology -MH - No-Reflow Phenomenon/diagnosis -MH - Sensitivity and Specificity -RF - 30 -EDAT- 2008/03/18 09:00 -MHDA- 2008/07/17 09:00 -CRDT- 2008/03/18 09:00 -PHST- 2008/03/18 09:00 [pubmed] -PHST- 2008/07/17 09:00 [medline] -PHST- 2008/03/18 09:00 [entrez] -AID - 10.1007/s00059-008-3110-8 [doi] -PST - ppublish -SO - Herz. 2008 Mar;33(2):129-35. doi: 10.1007/s00059-008-3110-8. - -PMID- 18326970 -OWN - NLM -STAT- MEDLINE -DCOM- 20080617 -LR - 20191110 -IS - 1559-4564 (Print) -IS - 1559-4564 (Linking) -VI - 3 -IP - 1 -DP - 2008 Winter -TI - Bayesian meta-analysis of tissue angiotensin-converting enzyme inhibitors for - reduction of adverse cardiovascular events in patients with diabetes mellitus and - preserved left ventricular function. -PG - 45-52 -AB - The role of angiotensin-converting enzyme (ACE) inhibitors in diabetic patients - with preserved ventricular function is uncertain. Tissue ACE inhibitors have been - defined by increased lipophilicity and structural characteristics that result in - greater tissue-specific ACE binding when compared with plasma ACE inhibitors. A - Bayesian meta-analysis of randomized trials was conducted to evaluate tissue ACE - inhibitors in prevention of cardiovascular disease among patients with diabetes - mellitus and preserved left ventricular function. Four trials were selected that - evaluated 2 different ACE inhibitors and included 10,328 patients (43,517 - patient-years). The Perindopril Substudy in Coronary Artery Disease and Diabetes - (PERSUADE) and the Perindopril Protection Against Recurrent Stroke Study - (PROGRESS) compared the effects of perindopril vs a placebo, and the Heart - Outcomes Prevention Evaluation (HOPE) and the Non-Insulin-Dependent Diabetes, - Hypertension, Microalbuminuria, Proteinuria, Cardiovascular Events, and Ramipril - (DIABHYCAR) study investigated the impact of ramipril vs a placebo. Bayesian - meta-analysis of sequential trials and sensitivity analysis of therapeutic - response were subsequently computed. Bayesian meta-analysis determined reduced - risk of cardiovascular mortality (PB=.991), myocardial infarction (PB=.999), and - the need for invasive coronary revascularization (PB=.995) when compared with - placebo. Total mortality was also decreased (PB=.967), while the risk of stroke - (PB=.907) and hospitalization for heart failure (PB=.923) were impacted. Bayesian - meta-analysis of randomized trials suggests that tissue ACE inhibitors decrease - the probability that diabetic patients with preserved left ventricular function - will experience myocardial infarctions and cardiovascular death and reduce - overall mortality. -FAU - Lang, Christopher D -AU - Lang CD -AD - Department of Medicine, Chicago Medical School, North Chicago, IL 60064, USA. - christopher.lang@rfums.org -FAU - Arora, Rohit R -AU - Arora RR -FAU - Saha, Sandeep A -AU - Saha SA -FAU - Molnar, Janos -AU - Molnar J -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PL - United States -TA - J Cardiometab Syndr -JT - Journal of the cardiometabolic syndrome -JID - 101284690 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Angiotensin-Converting Enzyme Inhibitors/metabolism/*therapeutic use -MH - Bayes Theorem -MH - Cardiovascular Diseases/*drug therapy -MH - Diabetes Mellitus/*drug therapy -MH - Humans -MH - Randomized Controlled Trials as Topic -MH - Risk Reduction Behavior -MH - Ventricular Function, Left -RF - 54 -EDAT- 2008/03/11 09:00 -MHDA- 2008/06/18 09:00 -CRDT- 2008/03/11 09:00 -PHST- 2008/03/11 09:00 [pubmed] -PHST- 2008/06/18 09:00 [medline] -PHST- 2008/03/11 09:00 [entrez] -AID - 10.1111/j.1559-4572.2008.07128.x [doi] -PST - ppublish -SO - J Cardiometab Syndr. 2008 Winter;3(1):45-52. doi: - 10.1111/j.1559-4572.2008.07128.x. - -PMID- 21816129 -OWN - NLM -STAT- MEDLINE -DCOM- 20121029 -LR - 20161222 -IS - 1556-3871 (Electronic) -IS - 1547-5271 (Linking) -VI - 9 -IP - 1 -DP - 2012 Jan -TI - Key role of the molecular autopsy in sudden unexpected death. -PG - 145-50 -LID - 10.1016/j.hrthm.2011.07.034 [doi] -AB - Sudden Cardiac Death (SCD) is a major and tragic complication of a number of - cardiovascular diseases. While in the older populations, SCD is most frequently - caused by underlying coronary artery disease and heart failure, in those aged - under 40 years, the causes of SCD commonly include genetic disorders, such as - inherited cardiomyopathies and primary arrhythmogenic diseases. As part of the - evaluation of families in which SCD has occurred, the role of genetic testing has - evolved as an important feature in both establishing an underlying diagnosis and - in screening at-risk family relatives. Specifically, in cases where no definitive - cause is identified at postmortem, i.e. Sudden Unexpected Death (SUD), the - "molecular autopsy" has emerged as a key process in the investigation of the - cause of death. The combination of clinical and genetic evaluation of families in - which SUD has occurred provides a platform for early initiation of therapeutic - and prevention strategies, with the ultimate goal to reduce sudden death among - the young in our communities. -CI - Copyright © 2012 Heart Rhythm Society. Published by Elsevier Inc. All rights - reserved. -FAU - Semsarian, Christopher -AU - Semsarian C -AD - Agnes Ginges Centre for Molecular Cardiology, Centenary Institute, Sydney, - Australia. c.semsarian@centenary.org.au -FAU - Hamilton, Robert M -AU - Hamilton RM -LA - eng -PT - Journal Article -PT - Review -DEP - 20110802 -PL - United States -TA - Heart Rhythm -JT - Heart rhythm -JID - 101200317 -SB - IM -MH - Autopsy/*methods -MH - Cardiovascular Diseases/complications/*diagnosis/genetics -MH - Death, Sudden, Cardiac/*etiology -MH - Genetic Predisposition to Disease -MH - Genetic Testing -MH - Humans -MH - *Pathology, Molecular -EDAT- 2011/08/06 06:00 -MHDA- 2012/10/30 06:00 -CRDT- 2011/08/06 06:00 -PHST- 2011/06/08 00:00 [received] -PHST- 2011/07/24 00:00 [accepted] -PHST- 2011/08/06 06:00 [entrez] -PHST- 2011/08/06 06:00 [pubmed] -PHST- 2012/10/30 06:00 [medline] -AID - S1547-5271(11)00902-7 [pii] -AID - 10.1016/j.hrthm.2011.07.034 [doi] -PST - ppublish -SO - Heart Rhythm. 2012 Jan;9(1):145-50. doi: 10.1016/j.hrthm.2011.07.034. Epub 2011 - Aug 2. - -PMID- 19485932 -OWN - NLM -STAT- MEDLINE -DCOM- 20100802 -LR - 20191027 -IS - 1875-6212 (Electronic) -IS - 1570-1611 (Linking) -VI - 8 -IP - 1 -DP - 2010 Jan -TI - Emerging P2Y12 receptor antagonists: role in coronary artery disease. -PG - 93-101 -AB - The use of oral antiplatelet therapy in reducing vascular events has been - extensively studied. Currently available oral antiplatelet agents include aspirin - and the thienopyridine P2Y12 receptor antagonists. These classes are combined - frequently in the setting of acute coronary syndrome and percutaneous coronary - intervention (PCI). Resistance to either or both of these agents is a major - concern, as antiplatelet resistance has been linked to an increase in thrombotic - events and worse clinical outcomes. As a result, there is a need for newer, more - effective antiplatelet agents to address the limitations of currently available - therapy. Prasugrel, a third generation thienopyridine, has been approved by both - the FDA and European Commission. Two additional P2Y12 agents, ticagrelor and - cangrelor are in advanced stages of development. The possible advantages of - prasugrel over clopidogrel include a faster onset of action, reduced - inter-patient variability and more potent platelet inhibition. Ticagrelor is an - oral reversible P2Y12 antagonist with greater platelet inhibition compared with - clopidogrel. Cangrelor is being developed as an intravenous P2Y12 antagonist with - a very fast onset and offset, which may offer advantages particularly in the - setting of coronary intervention. These emerging antiplatelet agents may offer - advantages such as faster onset of action, greater potency and reversibility of - platelet inhibition. This article summarizes the available clinical data on the - upcoming P2Y12 antiplatelet agents in the treatment of coronary artery disease. -FAU - Oliphant, Carrie S -AU - Oliphant CS -AD - Department of Pharmacy, Methodist University Hospital, University of Tennessee - College of Pharmacy, Memphis, TN 38104, USA. -FAU - Doby, J Bradford -AU - Doby JB -FAU - Blade, Crystal L -AU - Blade CL -FAU - Das, Kanak -AU - Das K -FAU - Mukherjee, Debabrata -AU - Mukherjee D -FAU - Das, Pranab -AU - Das P -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Vasc Pharmacol -JT - Current vascular pharmacology -JID - 101157208 -RN - 0 (P2RY12 protein, human) -RN - 0 (Piperazines) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Prodrugs) -RN - 0 (Purinergic P2 Receptor Antagonists) -RN - 0 (Receptors, Purinergic P2Y12) -RN - 0 (Thiophenes) -RN - 415SHH325A (Adenosine Monophosphate) -RN - 6AQ1Y404U7 (cangrelor) -RN - G89JQ59I13 (Prasugrel Hydrochloride) -RN - GLH0314RVC (Ticagrelor) -RN - K72T3FS567 (Adenosine) -SB - IM -MH - Adenosine/adverse effects/analogs & - derivatives/pharmacokinetics/pharmacology/therapeutic use -MH - Adenosine Monophosphate/adverse effects/analogs & - derivatives/pharmacokinetics/pharmacology/therapeutic use -MH - Animals -MH - Coronary Artery Disease/*drug therapy -MH - Humans -MH - Piperazines/adverse effects/pharmacokinetics/pharmacology/therapeutic use -MH - Platelet Aggregation Inhibitors/*pharmacology/*therapeutic use -MH - Prasugrel Hydrochloride -MH - Prodrugs/adverse effects/pharmacokinetics/pharmacology/therapeutic use -MH - *Purinergic P2 Receptor Antagonists -MH - Receptors, Purinergic P2Y12 -MH - Thiophenes/adverse effects/pharmacokinetics/pharmacology/therapeutic use -MH - Ticagrelor -RF - 69 -EDAT- 2009/06/03 09:00 -MHDA- 2010/08/03 06:00 -CRDT- 2009/06/03 09:00 -PHST- 2008/12/26 00:00 [received] -PHST- 2009/03/07 00:00 [accepted] -PHST- 2009/06/03 09:00 [entrez] -PHST- 2009/06/03 09:00 [pubmed] -PHST- 2010/08/03 06:00 [medline] -AID - CVP-Abs-007 [pii] -AID - 10.2174/157016110790226615 [doi] -PST - ppublish -SO - Curr Vasc Pharmacol. 2010 Jan;8(1):93-101. doi: 10.2174/157016110790226615. - -PMID- 19534658 -OWN - NLM -STAT- MEDLINE -DCOM- 20100524 -LR - 20191111 -IS - 2212-4063 (Electronic) -IS - 1871-529X (Linking) -VI - 9 -IP - 3 -DP - 2009 Sep -TI - Investigational positive inotropic agents for acute heart failure. -PG - 193-205 -AB - Acute heart failure represents a major public health problem due to its high - prevalence, high rates of mortality and readmissions and significant healthcare - costs. Patients with AHF and low cardiac output represent a small subgroup of - patients with very high mortality rates that require inotropic support to improve - cardiac systolic function. Classical inotropic agents, such as beta1-adrenergic - agonists (dobutamine, dopamine) and phosphodiesterase III inhibitors (milrinone, - enoximone) improve symptoms and hemodynamics by increasing free intracellular - Ca(2+) levels, but also increase myocardial O(2) demands and exert arrhythmogenic - effects. These actions explain why these drugs increase both short- and long-term - mortality, particularly in patients with AHF and coronary artery disease. Thus, - we need new inotropic agents that do not increase cytosolic Ca(2+) or myocardial - oxygen demands or produce arrhythmogenesis for the treatment of high-risk - patients with acute heart failure and low cardiac output. This review describes - three new classes of investigational agents: levosimendan, a calcium sensitizer - and potassium channel opener, istaroxime, the first new luso-inotropic agent and - cardiac myosin activators. -FAU - Tamargo, Juan -AU - Tamargo J -AD - Department of Pharmacology, School of Medicine, Universidad Complutense, Madrid, - Spain. jtamargo@med.ucm.es -FAU - Caballero, Ricardo -AU - Caballero R -FAU - Gómez, Ricardo -AU - Gómez R -FAU - Barana, Adriana -AU - Barana A -FAU - Amorós, Irene -AU - Amorós I -FAU - Delpón, Eva -AU - Delpón E -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Cardiovasc Hematol Disord Drug Targets -JT - Cardiovascular & hematological disorders drug targets -JID - 101269160 -RN - 0 (Cardiotonic Agents) -RN - 0 (Drugs, Investigational) -SB - IM -MH - Acute Disease -MH - Animals -MH - Cardiotonic Agents/pharmacology/*therapeutic use -MH - Clinical Trials as Topic/methods -MH - Drugs, Investigational/pharmacology/*therapeutic use -MH - Heart Failure/*drug therapy/metabolism -MH - Humans -RF - 82 -EDAT- 2009/06/19 09:00 -MHDA- 2010/05/25 06:00 -CRDT- 2009/06/19 09:00 -PHST- 2009/02/02 00:00 [received] -PHST- 2009/05/19 00:00 [accepted] -PHST- 2009/06/19 09:00 [entrez] -PHST- 2009/06/19 09:00 [pubmed] -PHST- 2010/05/25 06:00 [medline] -AID - CHDDT-3 [pii] -AID - 10.2174/187152909789007070 [doi] -PST - ppublish -SO - Cardiovasc Hematol Disord Drug Targets. 2009 Sep;9(3):193-205. doi: - 10.2174/187152909789007070. - -PMID- 28496751 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20201001 -IS - 1941-6911 (Print) -IS - 1941-6911 (Electronic) -IS - 1941-6911 (Linking) -VI - 5 -IP - 1 -DP - 2012 Jun-Jul -TI - Stroke and Death Prediction with the Impact of Vascular Disease in Patients with - Atrial Fibrillation. -PG - 586 -LID - 10.4022/jafib.586 [doi] -LID - 586 -AB - Atrial fibrillation (AF) is the most common arrhythmia encountered in the U.S. - and the growing burden of AF has profound health implications due to the - association of AF with an increased risk of stroke, heart failure, and mortality. - AF is a significant risk factor for thromboembolic stroke; and also independently - increases total mortality in patients with and without cardiovascular disease. - Various risk stratification schemes such as CHADS(2) and CHA(2)DS(2)-VASc have - been implemented in clinical practice to determine the risk of cardio-embolic - stroke, and need for thrombo-prophylaxis in patients with AF. AF is also closely - related to the pathophysiology of other cardiovascular and peripheral vascular - disease. Many patients with AF have associated atherosclerosis given that many - risk factors for atherosclerosis also predispose to AF. Myocardial infarction - (MI) is also closely related to AF and its clinical course is affected by new - onset AF. This review elucidates the impact of AF on major adverse cardiovascular - events and mortality outcomes in relation to stroke, coronary artery disease and - peripheral vascular disease. -FAU - Maan, Abhishek -AU - Maan A -AD - Department of Internal Medicine, University of Massachusetts Medical School, - Worcester, MA 01655. -FAU - Shaikh, Amir Y -AU - Shaikh AY -AD - Department of Internal Medicine, University of Massachusetts Medical School, - Worcester, MA 01655. -FAU - Mansour, Moussa -AU - Mansour M -AD - Cardiac Arrhythmia Service, Massachusetts General Hospital and Harvard Medical - School, GRB 109, 55 Fruit St, Boston MA 02115. -FAU - Ruskin, Jeremy N -AU - Ruskin JN -AD - Cardiac Arrhythmia Service, Massachusetts General Hospital and Harvard Medical - School, GRB 109, 55 Fruit St, Boston MA 02115. -FAU - Heist, E Kevin -AU - Heist EK -AD - Cardiac Arrhythmia Service, Massachusetts General Hospital and Harvard Medical - School, GRB 109, 55 Fruit St, Boston MA 02115. -LA - eng -PT - Journal Article -PT - Review -DEP - 20120615 -PL - United States -TA - J Atr Fibrillation -JT - Journal of atrial fibrillation -JID - 101514767 -PMC - PMC5153086 -EDAT- 2012/06/15 00:00 -MHDA- 2012/06/15 00:01 -PMCR- 2012/06/15 -CRDT- 2017/05/13 06:00 -PHST- 2012/03/08 00:00 [received] -PHST- 2012/05/15 00:00 [revised] -PHST- 2012/05/15 00:00 [accepted] -PHST- 2017/05/13 06:00 [entrez] -PHST- 2012/06/15 00:00 [pubmed] -PHST- 2012/06/15 00:01 [medline] -PHST- 2012/06/15 00:00 [pmc-release] -AID - 10.4022/jafib.586 [doi] -PST - epublish -SO - J Atr Fibrillation. 2012 Jun 15;5(1):586. doi: 10.4022/jafib.586. eCollection - 2012 Jun-Jul. - -PMID- 17237863 -OWN - NLM -STAT- MEDLINE -DCOM- 20070126 -LR - 20151119 -IS - 0807-7096 (Electronic) -IS - 0029-2001 (Linking) -VI - 127 -IP - 2 -DP - 2007 Jan 18 -TI - [Congestive heart failure--etiology and diagnostic procedures]. -PG - 171-3 -AB - Congestive heart failure is a major health problem in the western world and the - prevalence of patients with this diagnosis increases. About 2% of the adult - population are affected; the majority are elderly, which represents a challenge - when it comes to assessment and treatment. This article concerns the aetiology - and diagnosis of congestive heart failure and provides a suggestion for - guidelines. The proposed guidelines are aimed at primary, secondary and third - line health care providers in Norway, and are based on previously published - Norwegian guidelines and international guidelines. Hypertension and coronary - artery disease account for 75-80% of known cases of congestive heart failure. The - patient's history and risk factors must be investigated. Laboratory tests - emphasising organ functions are important, and these should include measurement - of B-type natriuretic peptide (BNP). Electrocardiograms and chest X-rays should - be taken as well. All patients with suspected impaired left ventricular ejection - fraction should undergo an echocardiographic examination. Invasive tests, and - non-invasive imaging should be used for selected groups of patients only. -FAU - Aarønaes, Marit -AU - Aarønaes M -AD - Hjertemedisinsk avdeling, Rikshospitalet, 0027 Oslo. - marit.aarones@rikshospitalet.no -FAU - Atar, Dan -AU - Atar D -FAU - Bonarjee, Vernon -AU - Bonarjee V -FAU - Gundersen, Torstein -AU - Gundersen T -FAU - Løchen, Maja-Lisa -AU - Løchen ML -FAU - Mo, Rune -AU - Mo R -FAU - Myhre, Eivind S P -AU - Myhre ES -FAU - Omland, Torbjørn -AU - Omland T -FAU - Rønnevik, Per K -AU - Rønnevik PK -FAU - Vegsundvåg, Johnny -AU - Vegsundvåg J -FAU - Westheim, Arne -AU - Westheim A -LA - nor -PT - English Abstract -PT - Journal Article -PT - Review -TT - Kronisk hjertesvikt--etiologi og diagnostikk. -PL - Norway -TA - Tidsskr Nor Laegeforen -JT - Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny - raekke -JID - 0413423 -RN - 0 (Biomarkers) -SB - IM -MH - Adult -MH - Aged -MH - Biomarkers/blood -MH - Echocardiography -MH - *Heart Failure/diagnosis/epidemiology/etiology -MH - Heart Function Tests -MH - Humans -MH - Middle Aged -MH - Prognosis -MH - Risk Factors -RF - 25 -EDAT- 2007/01/24 09:00 -MHDA- 2007/01/27 09:00 -CRDT- 2007/01/24 09:00 -PHST- 2007/01/24 09:00 [pubmed] -PHST- 2007/01/27 09:00 [medline] -PHST- 2007/01/24 09:00 [entrez] -AID - 1479331 [pii] -PST - ppublish -SO - Tidsskr Nor Laegeforen. 2007 Jan 18;127(2):171-3. - -PMID- 21247589 -OWN - NLM -STAT- MEDLINE -DCOM- 20110617 -LR - 20250626 -IS - 1097-685X (Electronic) -IS - 0022-5223 (Linking) -VI - 141 -IP - 5 -DP - 2011 May -TI - Short- and long-term mortality associated with new-onset atrial fibrillation - after coronary artery bypass grafting: a systematic review and meta-analysis. -PG - 1305-12 -LID - 10.1016/j.jtcvs.2010.10.040 [doi] -AB - OBJECTIVES: Our objectives were to evaluate short- and long-term mortality - associated with new-onset atrial fibrillation after coronary artery bypass - grafting and to identify preoperative and intraoperative patient characteristics - associated with new-onset atrial fibrillation. METHODS: Three independent - investigators comprehensively reviewed the literature using Medline from 1960, - Web of Science from 1980, and Scopus from 1960. All searches were done through - December 2009. Selected cohort studies were used to evaluate associations between - new-onset atrial fibrillation after coronary artery bypass grafting or coronary - bypass plus valve and short-term mortality (defined as 30-day or in-hospital - mortality) and long-term mortality (defined as mortality ≥ 6 months). We excluded - studies involving atrial flutter, off-pump coronary bypass, and isolated valve - surgery. Heterogeneity among studies was accounted for by meta-analysis with - random-effects models. RESULTS: Eleven studies (n = 40,112) met our inclusion - criteria. New-onset atrial fibrillation was associated with higher short-term - mortality (3.6% vs 1.9%; odds ratio [OR], 2.29; 95% confidence interval [CI], - 1.74-3.01; P < .00001; heterogeneity of effects, P = .002). Mortality risks at 1 - year and 4 years were 2.56 (95% CI, 2.14-3.08) and 2.19 (95% CI, 1.97-2.45; P < - .0001), respectively. Older age, lower ejection fraction, history of - hypertension, heart failure, prior stroke, peripheral arterial disease, and - longer cardiopulmonary bypass and aortic clamp times were associated with - new-onset atrial fibrillation. Preoperative use of ß-blockers reduced occurrence - of new-onset atrial fibrillation (OR, 0.94 [95% CI, 0.88-1.01; P = .08]), whereas - angiotensin-converting enzyme inhibitors increased it (OR, 1.20 [95% CI, - 1.11-1.29], P < .00001). CONCLUSIONS: New-onset atrial fibrillation after - coronary artery bypass grafting appears to increase short- and long-term - mortality. Preoperative use of ß-blockers, avoidance of angiotensin-converting - enzyme inhibitors, and shorter cardiopulmonary bypass and aortic clamp times - potentially reduce occurrence of new-onset atrial fibrillation. -CI - Copyright © 2011 The American Association for Thoracic Surgery. Published by - Mosby, Inc. All rights reserved. -FAU - Kaw, Roop -AU - Kaw R -AD - Department of Hospital Medicine, Medicine Institute, Cleveland Clinic, Cleveland, - Ohio 44195, USA. Kawr@ccf.org -FAU - Hernandez, Adrian V -AU - Hernandez AV -FAU - Masood, Iqbal -AU - Masood I -FAU - Gillinov, A Marc -AU - Gillinov AM -FAU - Saliba, Walid -AU - Saliba W -FAU - Blackstone, Eugene H -AU - Blackstone EH -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -DEP - 20110117 -PL - United States -TA - J Thorac Cardiovasc Surg -JT - The Journal of thoracic and cardiovascular surgery -JID - 0376343 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Aged -MH - Angiotensin-Converting Enzyme Inhibitors/adverse effects -MH - Aorta/surgery -MH - Atrial Fibrillation/etiology/*mortality/prevention & control -MH - Cardiopulmonary Bypass/adverse effects -MH - Chi-Square Distribution -MH - Constriction -MH - Coronary Artery Bypass/adverse effects/*mortality -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Odds Ratio -MH - Risk Assessment -MH - Risk Factors -MH - Time Factors -EDAT- 2011/01/21 06:00 -MHDA- 2011/06/18 06:00 -CRDT- 2011/01/21 06:00 -PHST- 2010/05/19 00:00 [received] -PHST- 2010/09/20 00:00 [revised] -PHST- 2010/10/24 00:00 [accepted] -PHST- 2011/01/21 06:00 [entrez] -PHST- 2011/01/21 06:00 [pubmed] -PHST- 2011/06/18 06:00 [medline] -AID - S0022-5223(10)01272-9 [pii] -AID - 10.1016/j.jtcvs.2010.10.040 [doi] -PST - ppublish -SO - J Thorac Cardiovasc Surg. 2011 May;141(5):1305-12. doi: - 10.1016/j.jtcvs.2010.10.040. Epub 2011 Jan 17. - -PMID- 23984365 -OWN - NLM -STAT- MEDLINE -DCOM- 20140318 -LR - 20211021 -IS - 2314-6141 (Electronic) -IS - 2314-6133 (Print) -VI - 2013 -DP - 2013 -TI - Sleep-disordered breathing in patients with heart failure: new trends in therapy. -PG - 459613 -LID - 10.1155/2013/459613 [doi] -LID - 459613 -AB - Heart failure (HF) is a growing health problem which paradoxically results from - the advances in the treatment of etiologically related diseases (especially - coronary artery disease). HF is commonly accompanied by sleep-disordered - breathing (SDB), which may directly exacerbate the clinical manifestations of - cardiovascular disease and confers a poorer prognosis. Obstructive sleep apnoea - predominates in mild forms while central sleep apnoea in more severe forms of - heart failure. Identification of SDB in patients with HF is important, as its - effective treatment may result in notable clinical benefits to the patients. - Continuous positive airway pressure (CPAP) is the gold standard in the management - of SDB. The treatments for central breathing disorders include CPAP, bilevel - positive airway pressure (BPAP), and adaptive servoventilation (ASV), with the - latter being the most modern method of treatment for the Cheyne-Stokes - respiration and involving ventilation support with a variable synchronisation - dependent on changes in airflow through the respiratory tract and on the - patient's respiratory rate. ASV exerts the most favourable effect on long-term - prognosis. In this paper, we review the current state of knowledge on the - diagnosis and treatment of SDB with a particular emphasis on the latest methods - of treatment. -FAU - Kazimierczak, Anna -AU - Kazimierczak A -AD - Department of Cardiology and Internal Diseases, Military Institute of Medicine, - Szaserow Street 128, 04-141 Warsaw, Poland. akazimierczak@wim.mil.pl -FAU - Krzesiński, Paweł -AU - Krzesiński P -FAU - Krzyżanowski, Krystian -AU - Krzyżanowski K -FAU - Gielerak, Grzegorz -AU - Gielerak G -LA - eng -PT - Journal Article -PT - Review -DEP - 20130728 -PL - United States -TA - Biomed Res Int -JT - BioMed research international -JID - 101600173 -SB - IM -EIN - Biomed Res Int. 2015;2015:375921. doi: 10.1155/2015/375921. PMID: 26605327 -MH - Cheyne-Stokes Respiration -MH - Heart Failure/*complications/*therapy -MH - Humans -MH - Noninvasive Ventilation -MH - Sleep Apnea Syndromes/*complications/*therapy -MH - Sleep Apnea, Central/complications/therapy -MH - Sleep Apnea, Obstructive/complications/therapy -PMC - PMC3745910 -EDAT- 2013/08/29 06:00 -MHDA- 2014/03/19 06:00 -PMCR- 2013/07/28 -CRDT- 2013/08/29 06:00 -PHST- 2013/04/23 00:00 [received] -PHST- 2013/07/02 00:00 [accepted] -PHST- 2013/08/29 06:00 [entrez] -PHST- 2013/08/29 06:00 [pubmed] -PHST- 2014/03/19 06:00 [medline] -PHST- 2013/07/28 00:00 [pmc-release] -AID - 10.1155/2013/459613 [doi] -PST - ppublish -SO - Biomed Res Int. 2013;2013:459613. doi: 10.1155/2013/459613. Epub 2013 Jul 28. - -PMID- 20015042 -OWN - NLM -STAT- MEDLINE -DCOM- 20100907 -LR - 20190823 -IS - 1875-533X (Electronic) -IS - 0929-8673 (Linking) -VI - 17 -IP - 4 -DP - 2010 -TI - New investigational drugs for the management of acute heart failure syndromes. -PG - 363-90 -AB - Acute heart failure syndromes (AHFS) enclose a broad spectrum of conditions with - different clinical presentations, heart failure history, pathophysiology, - prognosis and treatment. AHFS represent a major public health problem because of - their high prevalence, high rates of mortality and readmissions and significant - healthcare costs, and a therapeutic challenge for the clinicians because - management strategies vary markedly. Traditionally used drugs for the treatment - of AHFS, including diuretics, vasodilators and positive inotropics, improve - clinical signs and symptoms as well as hemodynamics, but present important - limitations, as they fail to reduce and may even increase in-hospital and - postdischarge mortality, especially in patients with coronary artery disease. - Thus, we need new pharmacological agents to not only improve signs and symptoms - and cardiac performance, but also improve both short- and long-term outcomes - (hospitalizations/survival). In the last decade, significant efforts have been - made to identify new therapeutic targets involved in the genesis/progression of - AHFS and to develop new therapeutic strategies that may safely improve outcomes. - As a result, several new families of drugs have been developed and are currently - studied in experimental models and in Phase II and III clinical trials, in an - attempt to define their efficacy and safety profiles as well as their precise - role in the treatment of AHFS patients. This review firstly analyzes the main - clinical applications and limitations of conventional drugs, and then focuses on - the mechanisms of action and effects of recently approved drugs and of new - investigational agents on signs, symptoms, hemodynamics and outcomes in AHFS - patients. -FAU - Tamargo, J -AU - Tamargo J -AD - Department of Pharmacology, School of Medicine, Universidad Complutense, Madrid, - Spain. jtamargo@med.ucm.es -FAU - Amorós, I -AU - Amorós I -FAU - Barana, A -AU - Barana A -FAU - Caballero, R -AU - Caballero R -FAU - Delpón, E -AU - Delpón E -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Cardiotonic Agents) -RN - 0 (Diuretics) -RN - 0 (Vasodilator Agents) -SB - IM -MH - Acute Disease/therapy -MH - Animals -MH - Cardiotonic Agents/pharmacology/therapeutic use -MH - Diuretics/pharmacology/therapeutic use -MH - Drug Discovery/*methods -MH - Heart Failure/classification/*drug therapy -MH - Humans -MH - Syndrome -MH - Vasodilator Agents/pharmacology/therapeutic use -RF - 195 -EDAT- 2009/12/18 06:00 -MHDA- 2010/09/08 06:00 -CRDT- 2009/12/18 06:00 -PHST- 2009/10/12 00:00 [received] -PHST- 2009/01/13 00:00 [accepted] -PHST- 2009/12/18 06:00 [entrez] -PHST- 2009/12/18 06:00 [pubmed] -PHST- 2010/09/08 06:00 [medline] -AID - CMC - AbsEpub/2010 - 025 [pii] -AID - 10.2174/092986710790192721 [doi] -PST - ppublish -SO - Curr Med Chem. 2010;17(4):363-90. doi: 10.2174/092986710790192721. - -PMID- 17558606 -OWN - NLM -STAT- MEDLINE -DCOM- 20070919 -LR - 20191110 -IS - 1381-3455 (Print) -IS - 1381-3455 (Linking) -VI - 113 -IP - 2 -DP - 2007 Apr -TI - Myocardial insulin action and the contribution of insulin resistance to the - pathogenesis of diabetic cardiomyopathy. -PG - 76-86 -AB - Heart disease is the leading cause of death in patients with insulin resistance - and type 2 diabetes (DM2). Even in the absence of coronary artery disease and - hypertension, functional and structural abnormalities exist in patients with - well-controlled and uncomplicated DM2. These derangements are collectively - designated by the term diabetic cardiomyopathy (DCM). Changes in myocardial - energy metabolism, due to altered substrate supply and utilization, largely - underlie the development of DCM. Insulin is an important regulator of myocardial - substrate metabolism, but also exerts regulatory effects on intracellular Ca2+ - handling and cell survival. The current paper reviews the multiple functional and - molecular effects of insulin on the heart, all of which ultimately seem to be - cardioprotective both under normal conditions and under ischemia. In particular, - the dismal consequences of myocardial insulin resistance contributing to the - development of DCM will be discussed. -FAU - Ouwens, D M -AU - Ouwens DM -AD - Department of Molecular Cell Biology, Leiden University Medical Centre, Leiden, - The Netherlands. d.m.ouwens@lumc.nl -FAU - Diamant, M -AU - Diamant M -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Arch Physiol Biochem -JT - Archives of physiology and biochemistry -JID - 9510153 -RN - 0 (Fatty Acids) -RN - 0 (Insulin) -RN - IY9XDZ35W2 (Glucose) -SB - IM -MH - Animals -MH - Cardiomyopathies/*etiology/*metabolism -MH - Diabetes Mellitus, Type 2/*complications/*metabolism -MH - Fatty Acids/metabolism -MH - Glucose/metabolism -MH - Humans -MH - Insulin/*physiology -MH - Insulin Resistance/*physiology -RF - 124 -EDAT- 2007/06/15 09:00 -MHDA- 2007/09/20 09:00 -CRDT- 2007/06/15 09:00 -PHST- 2007/06/15 09:00 [pubmed] -PHST- 2007/09/20 09:00 [medline] -PHST- 2007/06/15 09:00 [entrez] -AID - 779423181 [pii] -AID - 10.1080/13813450701422633 [doi] -PST - ppublish -SO - Arch Physiol Biochem. 2007 Apr;113(2):76-86. doi: 10.1080/13813450701422633. - -PMID- 22552953 -OWN - NLM -STAT- MEDLINE -DCOM- 20120813 -LR - 20211021 -IS - 1534-3170 (Electronic) -IS - 1523-3782 (Linking) -VI - 14 -IP - 3 -DP - 2012 Jun -TI - Diastolic stress test for the evaluation of exertional dyspnea. -PG - 359-65 -LID - 10.1007/s11886-012-0269-7 [doi] -AB - Recent studies have highlighted that dyspneic patients comprise a high-risk - subgroup of patients referred for cardiac stress testing. Even after adjusting - for the presence and degree of coronary artery disease the risk of cardiac and - all-cause mortality is at least three- to fivefold higher in dyspneic patients - compared to asymptomatic or those with chest pain. Stress echocardiography is - uniquely positioned to characterize all potential cardiovascular etiologies of - dyspnea from global and regional systolic dysfunction, myocardial ischemia to - valvular heart disease, pulmonary hypertension and diastolic dysfunction. Various - data point to diastolic dysfunction and associated heart failure as the major - potential etiology for dyspnea as well as the likely cause of the heightened - mortality risk. Doppler echocardiography at rest and with stress can now - characterize the hemodynamics of diastolic dysfunction and close the loop on the - comprehensive assessment of the patient who has exertional shortness of breath. - This review discusses the role of the Doppler echocardiographic diastolic stress - test in the evaluation of patients with cardiac dyspnea. -FAU - Kane, Garvan C -AU - Kane GC -AD - Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, 200 - First Street SW, Rochester, MN 55905, USA. Kane.Garvan@mayo.edu -FAU - Oh, Jae K -AU - Oh JK -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -SB - IM -MH - Blood Pressure/physiology -MH - Diastole/physiology -MH - Dyspnea/*diagnostic imaging/physiopathology -MH - Echocardiography, Stress/methods -MH - Exercise Test/*methods -MH - Humans -MH - Prognosis -MH - Pulmonary Artery/physiopathology -MH - Ventricular Function, Left/physiology -EDAT- 2012/05/04 06:00 -MHDA- 2012/08/14 06:00 -CRDT- 2012/05/04 06:00 -PHST- 2012/05/04 06:00 [entrez] -PHST- 2012/05/04 06:00 [pubmed] -PHST- 2012/08/14 06:00 [medline] -AID - 10.1007/s11886-012-0269-7 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2012 Jun;14(3):359-65. doi: 10.1007/s11886-012-0269-7. - -PMID- 20406084 -OWN - NLM -STAT- MEDLINE -DCOM- 20100610 -LR - 20100421 -IS - 1747-6348 (Print) -IS - 1747-6348 (Linking) -VI - 4 -IP - 2 -DP - 2010 Apr -TI - Cardiopulmonary exercise testing: current applications. -PG - 179-88 -LID - 10.1586/ers.10.8 [doi] -AB - Cardiopulmonary exercise testing (CPET) is under-utilized in assessing patients - with prominent complaints of dyspnea or exercise limitation and should be one of - the early tests used to assess exercise intolerance. The standard 12-lead ECG - treadmill stress test focuses on coronary artery disease and is inadequate to - assess the various subsystems (i.e., heart, lung, pulmonary vascular, peripheral - vascular, muscle and psychological motivation) that can contribute individually, - or more commonly in an interrelated fashion, to cause exercise limitation. The - additional gas exchange information from CPET is very helpful in the - identification of a more precise diagnosis, assessment of the severity of the - impairment, determination of response to treatment and prediction of mortality. - This special report will highlight some of the recent important applications of - CPET to clinical medicine with specific references to heart failure, preoperative - risk assessment, and regenerative and rehabilitative medicine, and the evidence - that currently exists in the medical literature to support routine CPET use. It - will also detail the recent evidence regarding the association of VO2max and - survival in health and disease. -FAU - Stringer, William W -AU - Stringer WW -AD - Harbor-UCLA Medical Center, Department of Medicine, 1000 W. Carson Street, Box - 400, Torrance, CA 90509, USA. stringer@ucla.edu -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Respir Med -JT - Expert review of respiratory medicine -JID - 101278196 -SB - IM -MH - Cardiac Output/physiology -MH - Cardiovascular Diseases/*diagnosis/*physiopathology -MH - Electrocardiography -MH - *Exercise Test -MH - Exercise Tolerance -MH - Humans -MH - Oxygen Consumption/physiology -MH - Predictive Value of Tests -MH - Pulmonary Gas Exchange -MH - Risk Assessment -MH - Stroke Volume/physiology -MH - Surgical Procedures, Operative -RF - 52 -EDAT- 2010/04/22 06:00 -MHDA- 2010/06/11 06:00 -CRDT- 2010/04/22 06:00 -PHST- 2010/04/22 06:00 [entrez] -PHST- 2010/04/22 06:00 [pubmed] -PHST- 2010/06/11 06:00 [medline] -AID - 10.1586/ers.10.8 [doi] -PST - ppublish -SO - Expert Rev Respir Med. 2010 Apr;4(2):179-88. doi: 10.1586/ers.10.8. - -PMID- 22364129 -OWN - NLM -STAT- MEDLINE -DCOM- 20120730 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 18 -IP - 11 -DP - 2012 -TI - Rheumatoid arthritis: cardiovascular manifestations, pathogenesis, and therapy. -PG - 1450-6 -AB - Rheumatoid Arthritis (RA) is a chronic progressive inflammatory joint disorder - that affects 0.5% - 1% of the general population. This review article discusses - cardiovascular manifestations of rheumatoid arthritis, pathogenesis of these - manifestations, and therapy. This disease not only affects the joints, but it - also involves other organ systems. The majority of these patients suffer - significant morbidity and mortality from cardiovascular disease. Cardiovascular - manifestations of RA include predilection for accelerated atherosclerosis and - endothelial dysfunction resulting in coronary artery disease (CAD), stroke, - congestive heart failure, and peripheral arterial disease. Some studies have - shown that the risk of developing CAD in RA patients is the same as for patients - with diabetes mellitus. These patients should be treated with aggressive medical - therapy such as disease modifying antirheumatic drugs, tumor necrosis factor - alpha inhibitors, and corticosteroids and with appropriate control of risk - factors such as smoking, dyslipidemia, hypertension, and obesity. Other - manifestations include pericarditis, myocarditis, and vasculitis. -FAU - Mellana, William M -AU - Mellana WM -AD - Cardiology Division, New York Medical College, Macy Pavilion, Room 138, Valhalla, - NY 10595, USA. -FAU - Aronow, Wilbert S -AU - Aronow WS -FAU - Palaniswamy, Chandrasekar -AU - Palaniswamy C -FAU - Khera, Sahil -AU - Khera S -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Anti-Inflammatory Agents) -SB - IM -MH - Anti-Inflammatory Agents/*therapeutic use -MH - Arthritis, Rheumatoid/*complications/*drug therapy -MH - Cardiovascular Diseases/*etiology/*prevention & control -MH - Humans -MH - Risk Assessment -EDAT- 2012/03/01 06:00 -MHDA- 2012/07/31 06:00 -CRDT- 2012/02/28 06:00 -PHST- 2011/12/16 00:00 [received] -PHST- 2012/01/10 00:00 [accepted] -PHST- 2012/02/28 06:00 [entrez] -PHST- 2012/03/01 06:00 [pubmed] -PHST- 2012/07/31 06:00 [medline] -AID - CPD-EPUB-20120224-002 [pii] -AID - 10.2174/138161212799504795 [doi] -PST - ppublish -SO - Curr Pharm Des. 2012;18(11):1450-6. doi: 10.2174/138161212799504795. - -PMID- 19400531 -OWN - NLM -STAT- MEDLINE -DCOM- 20090522 -LR - 20161124 -IS - 0004-4849 (Print) -IS - 0004-4849 (Linking) -VI - 100 -IP - 4 -DP - 2008 Oct-Dec -TI - Cardiac manifestations of amyloid disease. -PG - 60-70 -AB - Amyloidosis has been defined as an infiltrative disorder primarily caused by - extracellular tissue deposition of amyloid fibrils. There are at least twenty - five different human and eight different animal proteins precursors of amyloid - fibrils. Subtypes are differentiated by means of immunohistochemical and genetic - testing, with prognosis and therapeutic strategies different from each other. - There are a total of five types of amyloidosis: (1) Primary systemic amyloidosis, - (2) secondary systemic amyloidosis, (3) Senile amyloidosis, (4) Hereditary - amyloidosis, and (5) Hemodialysis-related. Cardiovascular manifestations can be - fourfold and include congestive heart failure due to restrictive cardiomyopathy, - vascular abnormalities, autonomic dysfunction, and conduction abnormalities. - Tissue diagnosis remains the goal standard for diagnosis ofamyloidosis. Non - invasive evaluation includes echocardiogram, cardiac MRI and Serum amyloid P - component scintigraphy. These studies will be helpful in the diagnosis as well as - follow up of patients with cardiac amyloidosis. Cardiac amyloidosis management - will vary depending on the subtype but consist of supportive treatment of cardiac - related symptoms and reducing the amyloid fibrils formation attacking the - underlying disease. -FAU - Rivera, Rafael J -AU - Rivera RJ -AD - Cardiology Section, Department of Medicine, VA Caribbean Healthcare System, - Puerto Rico, USA. -FAU - Vicenty, Sonia -AU - Vicenty S -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - Puerto Rico -TA - Bol Asoc Med P R -JT - Boletin de la Asociacion Medica de Puerto Rico -JID - 7505267 -SB - IM -MH - Age Factors -MH - Aged -MH - *Amyloidosis/classification/diagnosis/diagnostic - imaging/epidemiology/pathology/therapy -MH - Biopsy -MH - Cardiac Catheterization -MH - *Cardiomyopathies/diagnosis/diagnostic - imaging/pathology/physiopathology/surgery/therapy -MH - Coronary Angiography -MH - Diagnosis, Differential -MH - Echocardiography -MH - Electrocardiography -MH - Female -MH - Heart Transplantation -MH - Humans -MH - Magnetic Resonance Imaging -MH - Male -MH - Middle Aged -MH - Myocardium/pathology -MH - Prognosis -MH - Risk Factors -MH - Sex Factors -MH - Stroke Volume -RF - 50 -EDAT- 2009/04/30 09:00 -MHDA- 2009/05/23 09:00 -CRDT- 2009/04/30 09:00 -PHST- 2009/04/30 09:00 [entrez] -PHST- 2009/04/30 09:00 [pubmed] -PHST- 2009/05/23 09:00 [medline] -PST - ppublish -SO - Bol Asoc Med P R. 2008 Oct-Dec;100(4):60-70. - -PMID- 17313648 -OWN - NLM -STAT- MEDLINE -DCOM- 20070605 -LR - 20151119 -IS - 0742-2822 (Print) -IS - 0742-2822 (Linking) -VI - 24 -IP - 3 -DP - 2007 Mar -TI - Dobutamine stress magnetic resonance imaging. -PG - 309-15 -AB - Measurements of left ventricular function with cardiovascular magnetic resonance - (CMR) at rest and during intravenous dobutamine are useful for identifying - myocardial ischemia, viability, and the risk of subsequent cardiovascular events. - Without ionizing radiation, intravascular iodinated contrast administration, or - acoustic window limitations, CMR has emerged as a useful adjunct to transthoracic - echocardiography for assessing patients with or suspected of having coronary - artery disease. -FAU - Rerkpattanapipat, Pairoj -AU - Rerkpattanapipat P -AD - Perfect Heart Institute, Piyavate Hospital, Bangkok, Thailand. aemc@hotmail.com -FAU - Hundley, W Gregory -AU - Hundley WG -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Echocardiography -JT - Echocardiography (Mount Kisco, N.Y.) -JID - 8511187 -RN - 0 (Cardiotonic Agents) -RN - 3S12J47372 (Dobutamine) -SB - IM -MH - *Cardiotonic Agents -MH - *Dobutamine -MH - Exercise Test -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Myocardial Ischemia/*diagnosis -MH - Prognosis -MH - Ventricular Dysfunction, Left/*diagnosis -RF - 48 -EDAT- 2007/02/23 09:00 -MHDA- 2007/06/06 09:00 -CRDT- 2007/02/23 09:00 -PHST- 2007/02/23 09:00 [pubmed] -PHST- 2007/06/06 09:00 [medline] -PHST- 2007/02/23 09:00 [entrez] -AID - ECHO394 [pii] -AID - 10.1111/j.1540-8175.2007.00394.x [doi] -PST - ppublish -SO - Echocardiography. 2007 Mar;24(3):309-15. doi: 10.1111/j.1540-8175.2007.00394.x. - -PMID- 27325917 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20160621 -LR - 20231111 -IS - 1759-1104 (Print) -IS - 1759-1104 (Electronic) -IS - 1759-1104 (Linking) -VI - 1 -IP - 1 -DP - 2009 -TI - The evolving role of molecular imaging for coronary artery disease: where do we - stand today? -PG - 1-5 -LID - 10.1136/ha.2008.000273 [doi] -AB - The landscape of cardiac imaging is changing rapidly. There are promising new - developments in molecular imaging on the horizon. It is likely that nuclear - cardiology will continue to play an important role in the evaluation of CAD, but - that role must evolve to meet clinical needs, competing technologies and the - increasing emphasis on ensuring that imaging adds value and improves outcomes. - This review offers some suggestions on the optimal role nuclear imaging can play - vis-à-vis alternative options such as CT, but more data are needed before - definitive recommendations can be made. Randomised trials comparing different - diagnostic strategies can and should be performed to strengthen the foundations - of clinical practice in nuclear cardiology. An evidence-based approach to imaging - is here to stay. -FAU - Chua, T -AU - Chua T -LA - eng -PT - Journal Article -PT - Review -DEP - 20090101 -PL - England -TA - Heart Asia -JT - Heart Asia -JID - 101542742 -PMC - PMC4898487 -COIS- Competing interests: None. -EDAT- 2009/01/01 00:00 -MHDA- 2009/01/01 00:01 -PMCR- 2009/01/01 -CRDT- 2016/06/22 06:00 -PHST- 2008/12/22 00:00 [accepted] -PHST- 2016/06/22 06:00 [entrez] -PHST- 2009/01/01 00:00 [pubmed] -PHST- 2009/01/01 00:01 [medline] -PHST- 2009/01/01 00:00 [pmc-release] -AID - heartasia-2008-000273 [pii] -AID - 10.1136/ha.2008.000273 [doi] -PST - epublish -SO - Heart Asia. 2009 Jan 1;1(1):1-5. doi: 10.1136/ha.2008.000273. eCollection 2009. - -PMID- 17203427 -OWN - NLM -STAT- MEDLINE -DCOM- 20070221 -LR - 20171116 -IS - 0494-1373 (Print) -IS - 0494-1373 (Linking) -VI - 54 -IP - 4 -DP - 2006 -TI - Cardiovascular diseases in obstructive sleep apnea. -PG - 382-96 -AB - Obstructive sleep apnea (OSA) affects approximately 5% of women and 15% of men in - the middle-aged adults, and associated with adverse health outcomes. - Cardiovascular disturbances are the most serious complications of OSA. These - complications include heart failure, left/right ventricular dysfunction, acute - myocardial infarction, arrhythmias, stroke, systemic and pulmonary hypertension. - All these cardiovascular complications increase morbidity and mortality of OSA. - Several epidemiologic studies have demonstrated that sleep related breathing - disorders are an independent risk factor for hypertension, probably resulting - from a combination of intermittent hypoxia and hypercapnia, arousals, increased - sympathetic activity, and altered baroreflex control during sleep. Arterial - hypertension, obesity, diabetes mellitus and coronary artery disease (CAD) which - are independent predictors of left ventricular dysfunction, often have - co-existence with OSA. Especially severe OSA patients having diastolic - dysfunction might have an increased risk of heart failure, since diastolic - dysfunction might be combined with systolic dysfunction. Early recognition and - appropriate therapy of ventricular dysfunction is advisable to prevent further - progression to heart failure and death. Patients with acute myocardial - infarction, especially if they had apneas and hypoxemia without evident heart - failure should be evaluated for sleep disorders. So, patients with CAD should be - evaluated for OSA and vice versa. Early recognition and treatment of OSA may - improve cardiovascular functions. Continuous positive airway pressure (CPAP) - applied by nasal mask, is still the gold standard method for treatment of the - disease and prevention of complications. -FAU - Dursunoğlu, Dursun -AU - Dursunoğlu D -AD - Department of Cardiology, Faculty of Medicine, Pamukkale University, Denizli, - Turkey, and Department of Cardiology, Sahlgrenska University Hospital, Göteborg, - Sweden. dursundursunoglu@yahoo.com -FAU - Dursunoğlu, Neşe -AU - Dursunoğlu N -LA - eng -PT - Journal Article -PT - Review -PL - Turkey -TA - Tuberk Toraks -JT - Tuberkuloz ve toraks -JID - 0417364 -SB - IM -MH - Cardiovascular Diseases/*complications -MH - Humans -MH - Hypertension/complications -MH - Metabolic Syndrome/complications -MH - Sleep Apnea, Obstructive/*complications -RF - 132 -EDAT- 2007/01/05 09:00 -MHDA- 2007/02/22 09:00 -CRDT- 2007/01/05 09:00 -PHST- 2007/01/05 09:00 [pubmed] -PHST- 2007/02/22 09:00 [medline] -PHST- 2007/01/05 09:00 [entrez] -PST - ppublish -SO - Tuberk Toraks. 2006;54(4):382-96. - -PMID- 18431921 -OWN - NLM -STAT- MEDLINE -DCOM- 20080617 -LR - 20080424 -IS - 0033-2240 (Print) -IS - 0033-2240 (Linking) -VI - 64 Suppl 3 -DP - 2007 -TI - [Syncope in children and adolescents]. -PG - 76-9 -AB - The report presents a definition and causes of syncope in children. Syncope - differs from other states with loss of consciousness by causes leading to - decreased perfusion and resultant transient cerebral dysfunction with decreased - muscle tone. The most common causes of syncope noted in almost 15% of children - are neurocardiogenic. This group includes vasovagal, carotid sinus reflexive, - situational (coughing, dysphagia, micturation and defecation disturbances) and - post-exercise syncope. Another group is represented by orthostatic syncope that - may be triggered by primary and secondary dis-autonomy, decreased blood volume - (hemorrhage, diarrhea, Addison's disease), some medications and substances of - abuse (alcohol). An important group, accounting for 2%-6% of all cases, are - cardiogenic syncope, caused mainly by congenital/acquired obstructive cardiac - sub- and valvar heart defects, various cardiomyopathies, some heart tumors (e.g. - myxoma), exudative pericarditis, pulmonary embolus and hypertension, congenital - and acquired coronary anomalies, various significant brady-tachyarrhythmias (sick - sinus syndrome, supra- and ventricular tachycardias, congenital and acquired - atrio-ventricular blocks). Subclavian steal syndrome as the cause of syncope is - exceptional in children. Syncope does not include loss of consciousness due to - neurological and metabolic (hypoglycemia) causes, hypoxia, hyperventilation with - hypocapnia or CO intoxication. Differential diagnosis should also include - pseudo-syncope (hysteria). Preliminary diagnostic management should include a - detailed medical history, including family history, on the frequency and - circumstances of syncope, sudden deaths, a physical exam with orthostatic - assessment of peripheral blood pressure and standard ECG (heart rate, - intraventricular and atrioventricular conduction defects, cardiac hypertrophy, - arrhythmias, L-QT, changes in ST-T). Further specialist tests depend on - preliminary findings. -FAU - Rudziński, Andrzej -AU - Rudziński A -AD - Klinika Kardiologii Dzieciecej, Uniwersytet Jagielloński Collegium Medicum w - Krakowie. mikamins@cyf-kr.edu.pl -FAU - Oko-Lagan, Jolanta -AU - Oko-Lagan J -FAU - Kuźma, Jacek -AU - Kuźma J -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Omdlenia u dzieci i młodocianych. -PL - Poland -TA - Przegl Lek -JT - Przeglad lekarski -JID - 19840720R -SB - IM -MH - Adolescent -MH - Child -MH - Diagnosis, Differential -MH - Humans -MH - Syncope/*diagnosis/*etiology -RF - 16 -EDAT- 2008/04/25 09:00 -MHDA- 2008/06/18 09:00 -CRDT- 2008/04/25 09:00 -PHST- 2008/04/25 09:00 [pubmed] -PHST- 2008/06/18 09:00 [medline] -PHST- 2008/04/25 09:00 [entrez] -PST - ppublish -SO - Przegl Lek. 2007;64 Suppl 3:76-9. - -PMID- 17503881 -OWN - NLM -STAT- MEDLINE -DCOM- 20070807 -LR - 20181025 -IS - 1175-3277 (Print) -IS - 1175-3277 (Linking) -VI - 7 -IP - 2 -DP - 2007 -TI - Evidence-based medical therapy of patients with acute coronary syndromes. -PG - 95-116 -AB - Acute coronary syndromes (ACS) present a major health challenge in modern - medicine. With new clinical trials being conducted, our knowledge of latest - therapies for ACS continually evolves. In this article, we review currently - available medical therapies and provide evidence-based rationale for current - pharmacologic therapies. Among the antiplatelet therapies, aspirin, clopidogrel, - and glycoprotein IIb/IIIa inhibitors demonstrate significant efficacy in reducing - morbidity and mortality. Among the anticoagulants, unfractionated heparin and low - molecular weight heparin, particularly enoxaparin sodium, remain the hallmarks of - therapy against which newer anticoagulants are often compared. Bivalirudin has - recently showed significant efficacy in decreasing cardiovascular events and - mortality, but with potentially less risk of bleeding than heparin. Results of - trials evaluating warfarin remain inconsistent regarding potential benefits. - Finally, fondaparinux sodium, recently tested, shows promise as a powerful yet - safe anticoagulant. Fibrinolysis is an acceptable modality for reperfusion if - facilities equipped for primary percutaneous revascularization are not available. - Regarding anti-ischemic therapy, beta-adrenoceptor antagonists and nitrates - remain critical in the early management of ACS. Inhibitors of the - renin-angiotensin-aldosterone system have also shown significant reductions in - the morbidity and mortality of patients presenting with ACS, particularly in - patients with left ventricular dysfunction and clinical heart failure, with ACE - inhibitors being first-line agents and angiotensin receptor antagonists being a - reasonable substitute if ACE inhibitors are not tolerated. Among the - lipid-lowering therapies, statins (HMG-CoA reductase inhibitors) have been - documented as being the most well tolerated and most efficacious therapies for - ACS patients and data exist that they should be administered early in ACS - management. Studies evaluating combination therapy (antiplatelet drugs, - beta-adrenoceptor antagonists, ACE inhibitors, and lipid-lowering agents) show a - clear benefit in mortality in patients with known coronary artery disease. - Efforts to improve these key evidence-based medical therapies are numerous and - include such programs as the American College of Cardiology's Guidelines Applied - in Practice, international patient registries such as the Global Registry of - Acute Coronary Events, and studies such as CRUSADE. Finally, patients with - diabetes mellitus pose a challenge to clinicians both in terms of their glycemic - control and in their apparent relative resistance to antiplatelet therapy. - Studies involving ACS patients suggest that stringent glycemic control may result - in benefits in both morbidity and mortality. -FAU - Ramanath, Vijay S -AU - Ramanath VS -AD - University of Michigan Medical Center, 300 N. Ingalls, Ann Arbor, MI 48109, USA. - vijayr@med.umich.edu -FAU - Eagle, Kim A -AU - Eagle KA -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -RN - 0 (Anticoagulants) -RN - 0 (Cardiovascular Agents) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Hypolipidemic Agents) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Acute Disease -MH - Angina, Unstable/diagnosis/*drug therapy -MH - Anticoagulants/pharmacology/therapeutic use -MH - Cardiovascular Agents/pharmacology/therapeutic use -MH - Diabetes Mellitus, Type 2/complications -MH - Drug Therapy, Combination -MH - Evidence-Based Medicine -MH - Fibrinolytic Agents/pharmacology/therapeutic use -MH - Humans -MH - Hypolipidemic Agents/pharmacology/therapeutic use -MH - Myocardial Infarction/diagnosis/*drug therapy -MH - Platelet Aggregation Inhibitors/pharmacology/*therapeutic use -MH - Practice Guidelines as Topic -RF - 91 -EDAT- 2007/05/17 09:00 -MHDA- 2007/08/08 09:00 -CRDT- 2007/05/17 09:00 -PHST- 2007/05/17 09:00 [pubmed] -PHST- 2007/08/08 09:00 [medline] -PHST- 2007/05/17 09:00 [entrez] -AID - 722 [pii] -AID - 10.2165/00129784-200707020-00002 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2007;7(2):95-116. doi: 10.2165/00129784-200707020-00002. - -PMID- 18722191 -OWN - NLM -STAT- MEDLINE -DCOM- 20081021 -LR - 20080825 -IS - 0002-9149 (Print) -IS - 0002-9149 (Linking) -VI - 102 -IP - 5A -DP - 2008 Sep 8 -TI - Surgical therapies for post-myocardial infarction patients. -PG - 42G-46G -LID - 10.1016/j.amjcard.2008.06.010 [doi] -AB - Occasionally, high-risk patients in the post-myocardial infarction (MI) period - require surgical intervention for stabilization and/or revascularization. In a - meta-analysis involving 3,088 patients with ischemic heart disease, - revascularization was associated with nearly an 80% reduction in the risk of - death. Coronary artery bypass graft (CABG) surgery is commonly performed in - post-MI patients and is associated with more favorable outcomes than medical - therapy. However, several factors have to be considered in proper patient - selection for CABG, such as the left ventricular ejection fraction (LVEF), - severity of heart failure (HF), and myocardial viability. The ongoing Surgical - Treatment for Ischemic Heart Failure (STICH) trial will assess the benefits of - CABG in patients with both a low LVEF and HF. Unstable post-MI patients who fail - revascularization can be managed via mechanical circulatory support devices or - pumps. These options significantly improve hemodynamic parameters. In addition, - other surgical techniques, such as mitral valve repair, ventricular - reconstruction surgery, and atrial fibrillation ablation, are being evaluated in - patients with ischemic heart disease. -FAU - McCarthy, Patrick M -AU - McCarthy PM -AD - Division of Cardiothoracic Surgery, Feinberg School of Medicine, Northwestern - University, Chicago, Illinois 60611-2908, USA. pmccart@nmh.org -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -SB - IM -MH - Death, Sudden, Cardiac/etiology/*prevention & control -MH - Humans -MH - Myocardial Infarction/*complications -MH - Myocardial Revascularization/*methods -MH - Risk Factors -MH - Treatment Outcome -RF - 22 -EDAT- 2008/10/03 09:00 -MHDA- 2008/10/22 09:00 -CRDT- 2008/10/03 09:00 -PHST- 2008/10/03 09:00 [pubmed] -PHST- 2008/10/22 09:00 [medline] -PHST- 2008/10/03 09:00 [entrez] -AID - S0002-9149(08)01000-X [pii] -AID - 10.1016/j.amjcard.2008.06.010 [doi] -PST - ppublish -SO - Am J Cardiol. 2008 Sep 8;102(5A):42G-46G. doi: 10.1016/j.amjcard.2008.06.010. - -PMID- 19716310 -OWN - NLM -STAT- MEDLINE -DCOM- 20110111 -LR - 20100203 -IS - 1873-734X (Electronic) -IS - 1010-7940 (Linking) -VI - 37 -IP - 1 -DP - 2010 Jan -TI - Chronic ischaemic mitral regurgitation. Current treatment results and new - mechanism-based surgical approaches. -PG - 170-85 -LID - 10.1016/j.ejcts.2009.07.008 [doi] -AB - Chronic ischaemic mitral regurgitation (CIMR) remains one of the most complex and - unresolved aspects in the management of ischaemic heart disease. This review - provides an overview of the present knowledge about the different aspects of CIMR - with an emphasis on mechanisms, current surgical treatment results and new - mechanism-based surgical approaches. CIMR occurs in approximately 20-25% of - patients followed up after myocardial infarction (MI) and in 50% of those with - post-infarct congestive heart failure (CHF). The presence of CIMR adversely - affects prognosis, increasing mortality and the risk of CHF in a graded fashion - according to CIMR severity. The primary mechanism of CIMR is ischaemia-induced - left ventricular (LV) remodelling with papillary muscle displacement and apical - tenting of the mitral valve leaflets. CIMR is often clinically silent, and - colour-Doppler echocardiography remains the most reliable diagnostic tool. The - most commonly performed surgical procedure for CIMR (restrictive annuloplasty - combined with coronary artery bypass grafting (CABG)) can provide good results in - selected patients with minimal LV dilatation and minimal tenting. However, in - general the persistence and recurrence rate (at least MR grade 3+) for - restrictive annuloplasty remains high (up to 30% at 6 months postoperatively), - and after a 10-year follow-up there does not appear to be a survival benefit of a - combined procedure compared to CABG alone (10-year survival rate for both is - approximately 50%). Patients at risk of annuloplasty failure based on - preoperative echocardiographic and clinical parameters may benefit from mitral - valve replacement with preservation of the subvalvular apparatus or from new - alternative procedures targeting the subvalvular apparatus including the LV. - These new procedures include second-order chordal cutting, papillary muscle - repositioning by a variety of techniques and ventricular approaches using - external ventricular restraint devices or the Coapsys device. In addition, - percutaneous transvenous repair techniques are being developed. Although - promising, at this point these new procedures still lack investigation in large - patient cohorts with long-term follow-up. They will, however, be the subject of - much anticipated and necessary ongoing and future research. -CI - Copyright 2009 European Association for Cardio-Thoracic Surgery. Published by - Elsevier B.V. All rights reserved. -FAU - Bouma, Wobbe -AU - Bouma W -AD - Department of Cardiothoracic Surgery, University Medical Center Groningen, - Groningen, The Netherlands. w.bouma@thorax.umcg.nl -FAU - van der Horst, Iwan C C -AU - van der Horst IC -FAU - Wijdh-den Hamer, Inez J -AU - Wijdh-den Hamer IJ -FAU - Erasmus, Michiel E -AU - Erasmus ME -FAU - Zijlstra, Felix -AU - Zijlstra F -FAU - Mariani, Massimo A -AU - Mariani MA -FAU - Ebels, Tjark -AU - Ebels T -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090827 -PL - Germany -TA - Eur J Cardiothorac Surg -JT - European journal of cardio-thoracic surgery : official journal of the European - Association for Cardio-thoracic Surgery -JID - 8804069 -SB - IM -CIN - Eur J Cardiothorac Surg. 2010 Oct;38(4):510; author reply 510-1. doi: - 10.1016/j.ejcts.2010.03.001. PMID: 20363147 -MH - Chronic Disease -MH - Coronary Artery Bypass -MH - Heart Valve Prosthesis Implantation/methods -MH - Humans -MH - Mitral Valve/pathology -MH - Mitral Valve Insufficiency/diagnosis/etiology/*surgery -MH - Myocardial Infarction/complications -MH - Myocardial Ischemia/*complications -MH - Prognosis -EDAT- 2009/09/01 06:00 -MHDA- 2011/01/12 06:00 -CRDT- 2009/09/01 09:00 -PHST- 2009/04/29 00:00 [received] -PHST- 2009/06/30 00:00 [revised] -PHST- 2009/07/06 00:00 [accepted] -PHST- 2009/09/01 09:00 [entrez] -PHST- 2009/09/01 06:00 [pubmed] -PHST- 2011/01/12 06:00 [medline] -AID - S1010-7940(09)00698-8 [pii] -AID - 10.1016/j.ejcts.2009.07.008 [doi] -PST - ppublish -SO - Eur J Cardiothorac Surg. 2010 Jan;37(1):170-85. doi: 10.1016/j.ejcts.2009.07.008. - Epub 2009 Aug 27. - -PMID- 19204066 -OWN - NLM -STAT- MEDLINE -DCOM- 20090813 -LR - 20111117 -IS - 1943-4456 (Electronic) -IS - 0091-7451 (Linking) -VI - 73 -DP - 2008 -TI - Multipotent islet-1 cardiovascular progenitors in development and disease. -PG - 297-306 -LID - 10.1101/sqb.2008.73.055 [doi] -AB - During the past several years, advances at the intersection of cardiovascular - development and heart stem cell biology have begun to reshape our view of the - fundamental logic that drives the formation of discrete tissue components in the - mammalian heart. Although many of the critical genes that control cardiac - myogenesis have been identified, our understanding of how a highly diverse and - specialized subset of heart cell lineages arises from mesodermal precursors and - is subsequently assembled into distinct muscle chambers, coronary arterial tree - and large vessels, valvular tissue, and conduction system/pacemaker cells remains - at a relatively primitive stage. Recent studies have uncovered a diverse group of - closely related heart progenitors that are central in controlling and - coordinating these complex steps of cardiogenesis. Understanding the pathways - that control their formation, renewal, and subsequent conversion to specific - differentiated progeny forms the underpinning for unraveling the pathways for - congenital heart disease and has direct relevance to cardiovascular regenerative - medicine. This current brief review highlights the discovery and delineation of - the role of Islet-1 cardiovascular progenitors in the generation of diverse heart - cell lineages and how the implications of these findings are revising our - classification and thinking about congenital heart disease in general. -FAU - Nakano, A -AU - Nakano A -AD - Cardiovascular Research Center, Massachusetts General Hospital, Harvard Stem Cell - Institute, Harvard Medical School, Boston, Massachusetts 02114-2790, USA. -FAU - Nakano, H -AU - Nakano H -FAU - Chien, K R -AU - Chien KR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090209 -PL - United States -TA - Cold Spring Harb Symp Quant Biol -JT - Cold Spring Harbor symposia on quantitative biology -JID - 1256107 -RN - 0 (Homeodomain Proteins) -RN - 0 (LIM-Homeodomain Proteins) -RN - 0 (Transcription Factors) -RN - 0 (Wnt Proteins) -RN - 0 (beta Catenin) -RN - 0 (insulin gene enhancer binding protein Isl-1) -SB - IM -MH - Animals -MH - Cell Differentiation -MH - Fetal Heart/*cytology/embryology/*metabolism -MH - Heart Defects, Congenital/embryology/metabolism/pathology -MH - Homeodomain Proteins/genetics/*metabolism -MH - Humans -MH - LIM-Homeodomain Proteins -MH - Mice -MH - Models, Cardiovascular -MH - Multipotent Stem Cells/*cytology/*metabolism -MH - Myoblasts, Cardiac/*cytology/*metabolism -MH - Signal Transduction -MH - Transcription Factors -MH - Wnt Proteins/metabolism -MH - beta Catenin/metabolism -RF - 115 -EDAT- 2009/02/11 09:00 -MHDA- 2009/08/14 09:00 -CRDT- 2009/02/11 09:00 -PHST- 2009/02/11 09:00 [entrez] -PHST- 2009/02/11 09:00 [pubmed] -PHST- 2009/08/14 09:00 [medline] -AID - sqb.2008.73.055 [pii] -AID - 10.1101/sqb.2008.73.055 [doi] -PST - ppublish -SO - Cold Spring Harb Symp Quant Biol. 2008;73:297-306. doi: 10.1101/sqb.2008.73.055. - Epub 2009 Feb 9. - -PMID- 17113398 -OWN - NLM -STAT- MEDLINE -DCOM- 20070612 -LR - 20071115 -IS - 1555-7162 (Electronic) -IS - 0002-9343 (Linking) -VI - 119 -IP - 12 Suppl 1 -DP - 2006 Dec -TI - Congestion in acute heart failure syndromes: an essential target of evaluation - and treatment. -PG - S3-S10 -AB - Patients with acute heart failure syndromes (AHFS) typically present with signs - and symptoms of systemic and pulmonary congestion at admission. However, elevated - left ventricular (LV) filling pressures (hemodynamic congestion) may be present - days or weeks before systemic and pulmonary congestion develop, resulting in - hospital admission. This "hemodynamic congestion," with or without clinical - congestion, may have deleterious effects including subendocardial ischemia, - alterations in LV geometry resulting in secondary mitral insufficiency, and - impaired cardiac venous drainage from coronary veins resulting in diastolic - dysfunction. It is possible that these hemodynamic abnormalities in addition to - neurohormonal activation may contribute to LV remodeling and heart failure - progression. Approximately 50% of patients admitted for AHFS are discharged with - persistent symptoms and/or minimal or no weight loss in spite of the fact that - the main reason for admission was clinical congestion. Accordingly, the - assessment and management of pulmonary and systemic congestion in these patients - require reevaluation. -FAU - Gheorghiade, Mihai -AU - Gheorghiade M -AD - Division of Cardiology, Northwestern University Feinberg School of Medicine, - Chicago, Illinois, USA. m-gheorghiade@northwestern.edu -FAU - Filippatos, Gerasimos -AU - Filippatos G -FAU - De Luca, Leonardo -AU - De Luca L -FAU - Burnett, John -AU - Burnett J -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Med -JT - The American journal of medicine -JID - 0267200 -SB - IM -CIN - Am J Med. 2006 Dec;119(12 Suppl 1):S1-2. doi: 10.1016/j.amjmed.2006.09.010. PMID: - 17113394 -MH - Acute Disease -MH - Blood Pressure -MH - Blood Volume -MH - Dyspnea/etiology -MH - Edema/etiology -MH - Heart Failure/complications/*physiopathology/therapy -MH - Hospitalization -MH - Humans -MH - Prognosis -MH - Syndrome -MH - Ventricular Dysfunction, Left/diagnosis/*physiopathology -MH - Ventricular Remodeling/physiology -MH - Water-Electrolyte Balance -RF - 50 -EDAT- 2006/11/23 09:00 -MHDA- 2007/08/24 09:00 -CRDT- 2006/11/23 09:00 -PHST- 2006/11/23 09:00 [pubmed] -PHST- 2007/08/24 09:00 [medline] -PHST- 2006/11/23 09:00 [entrez] -AID - S0002-9343(06)01141-7 [pii] -AID - 10.1016/j.amjmed.2006.09.011 [doi] -PST - ppublish -SO - Am J Med. 2006 Dec;119(12 Suppl 1):S3-S10. doi: 10.1016/j.amjmed.2006.09.011. - -PMID- 21416840 -OWN - NLM -STAT- MEDLINE -DCOM- 20110506 -LR - 20191210 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 11 -IP - 10 Suppl 1 -DP - 2010 Oct -TI - [Drugs and athletic activity: do they fit together?]. -PG - 118S-121S -AB - Competitive sports eligibility, mandatory for the Italian law in all age classes, - from young to master athletes, involves millions of subjects, who are at risk - during their sport career both for prescription and illicit drugs (or banned - substances included in the World Anti-Doping Agency list, annually updated). - These drugs may interfere with adrenergic hyperactivation related to athletic - activity and can bring to unfavorable cardiovascular effects, such as - arrhythmias, coronary artery disease, myocarditis, pericarditis, heart failure, - ion channel disease. Moreover, numerous compounds may reduce athletic - performance. Cardiovascular side effects are more frequently reported when drug - co-administration is performed, which occurs frequently. Drug co-administration - may have a higher risk when a common metabolic pathway is used (i.e. P450 hepatic - cytochrome), and inhibition or induction effects modify plasma drug levels. One - of the most important problems remains for combination of drugs that might be - torsadogenic. Therefore, it is mandatory to be aware of pharmacokinetic - properties, mechanisms of action, side effects and interactions between drugs and - competitive sports activities; moreover, possible clinical, instrumental (i.e. - ECG) or laboratory markers should be pointed out in order to recognize a possible - toxic effect and subsequently interrupt or modify drug administration and/or - assumption. -FAU - Furlanello, Francesco -AU - Furlanello F -AD - Centro di Aritmologia Clinica ed Elettrofisiologia, IRCCS Policlinico San Donato, - San Donato Milanese (MI). ffurlanello@villabiancatrento.it -FAU - Serdoz, Laura Vitali -AU - Serdoz LV -FAU - Botrè, Francesco -AU - Botrè F -FAU - Accettura, Domenico -AU - Accettura D -FAU - Lestuzzi, Chiara -AU - Lestuzzi C -FAU - De Ambroggi, Luigi -AU - De Ambroggi L -FAU - Cappato, Riccardo -AU - Cappato R -LA - ita -PT - Comparative Study -PT - Journal Article -PT - Review -TT - Quanto sono compatibili i farmaci con l'attività atletica. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -RN - 0 (Illicit Drugs) -SB - IM -MH - Arrhythmias, Cardiac/chemically induced -MH - *Athletes -MH - Cardiovascular Diseases/chemically induced -MH - *Doping in Sports/legislation & jurisprudence -MH - Drug Prescriptions -MH - Electrocardiography -MH - Heart Diseases/*chemically induced -MH - Humans -MH - Iatrogenic Disease -MH - Illicit Drugs/*adverse effects -MH - Italy -MH - Long QT Syndrome/chemically induced -MH - Risk Factors -MH - Torsades de Pointes/chemically induced -EDAT- 2011/03/23 06:00 -MHDA- 2011/05/07 06:00 -CRDT- 2011/03/23 06:00 -PHST- 2011/03/23 06:00 [entrez] -PHST- 2011/03/23 06:00 [pubmed] -PHST- 2011/05/07 06:00 [medline] -PST - ppublish -SO - G Ital Cardiol (Rome). 2010 Oct;11(10 Suppl 1):118S-121S. - -PMID- 17470336 -OWN - NLM -STAT- MEDLINE -DCOM- 20070619 -LR - 20191110 -IS - 1523-3782 (Print) -IS - 1523-3782 (Linking) -VI - 9 -IP - 3 -DP - 2007 May -TI - Prevalence and management of chronotropic incompetence in heart failure. -PG - 229-35 -AB - Although chronotropic incompetence (CI) has been shown to have important - prognostic value in asymptomatic and coronary artery disease populations, much - less attention has been given to the prevalence and impact of CI in heart - failure. There is considerable variability in the reported prevalence of - chronotropic impairment (25%-70%) in the heart failure literature, likely due to - a lack of a standardized definition and/or differing assessment methodologies. - Although the exact prevalence of CI is debatable and the precise pathophysiologic - mechanisms involved remain uncertain, there is unambiguous evidence indicating - that chronotropic impairment contributes significantly to the myriad of - cardiovascular, neuromuscular, pulmonary, and neurohormonal maladaptations known - to negatively impact the physical functional and quality of life of most heart - failure patients. Specifically, an inappropriate chronotropic response to - exercise can decrease peak exercise oxygen uptake by as much as 15% to 20%. - Therapeutic interventions to improve chronotropic function, including endurance - exercise training and rate-adaptive pacing, although promising, still warrant - further investigation. -FAU - Brubaker, Peter H -AU - Brubaker PH -AD - Departments of Health and Exercise Science, Section on Internal Medicine - (Cardiology), Wake Forest University, Box 7628, Reynolda Station, Winston-Salem, - NC 27109, USA. brubaker@wfu.edu -FAU - Kitzman, Dalane W -AU - Kitzman DW -LA - eng -GR - R37 AG018915/AG/NIA NIH HHS/United States -GR - AG12257/AG/NIA NIH HHS/United States -GR - AG18915/AG/NIA NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -SB - IM -MH - Animals -MH - Exercise -MH - Heart Failure/epidemiology/*physiopathology -MH - *Heart Rate -MH - Humans -MH - Prevalence -RF - 47 -EDAT- 2007/05/02 09:00 -MHDA- 2007/06/20 09:00 -CRDT- 2007/05/02 09:00 -PHST- 2007/05/02 09:00 [pubmed] -PHST- 2007/06/20 09:00 [medline] -PHST- 2007/05/02 09:00 [entrez] -AID - 10.1007/BF02938355 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2007 May;9(3):229-35. doi: 10.1007/BF02938355. - -PMID- 16969671 -OWN - NLM -STAT- MEDLINE -DCOM- 20070228 -LR - 20181113 -IS - 0020-9554 (Print) -IS - 0020-9554 (Linking) -VI - 47 -IP - 10 -DP - 2006 Oct -TI - [Ventricular tachycardia. Diagnostic spectrum and therapeutic measures]. -PG - 1001-4, 1006-8, 1010-2 -AB - The origin of ventricular tachycardia lies in the ventricular tissue and includes - a variety of symptoms such as monomorphic and polymorphic ventricular - tachyarrhythmia (VT), ventricular flutter and ventricular fibrillation. Due to - transitions of one form of VT to another, any form of VT incurs in principal the - risk of cardiac failure. Apart from different electrophysiologic mechanisms such - as reentry or triggered activity, any occurrence of VT has to be considered in an - individual context: VT can be caused by structural heart disease such as coronary - artery disease or dilative cardiomyopathy, or primary electrical disease such as - long or short QT syndromes or can even occur without any detectable cause - (idiopathic VT). Correct identification of the underlying cause of the arrhythmia - is essential for the prognosis, differential therapy and long-term treatment of - patients. -FAU - Lewalter, T -AU - Lewalter T -AD - Medizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, - Sigmund-Freud-Strasse 25, 53105, Bonn, Germany. th.lewalter@uni-bonn.de -FAU - Schwab, J O -AU - Schwab JO -FAU - Nickenig, G -AU - Nickenig G -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Ventrikuläre Tachykardien. Diagnostisches Spektrum und therapeutische - Möglichkeiten. -PL - Germany -TA - Internist (Berl) -JT - Der Internist -JID - 0264620 -SB - IM -MH - Catheter Ablation -MH - Death, Sudden, Cardiac/etiology/prevention & control -MH - Defibrillators, Implantable -MH - Electrocardiography -MH - Humans -MH - Risk Factors -MH - Tachycardia, Ventricular/diagnosis/etiology/*therapy -RF - 31 -EDAT- 2006/09/14 09:00 -MHDA- 2007/03/01 09:00 -CRDT- 2006/09/14 09:00 -PHST- 2006/09/14 09:00 [pubmed] -PHST- 2007/03/01 09:00 [medline] -PHST- 2006/09/14 09:00 [entrez] -AID - 10.1007/s00108-006-1708-6 [doi] -PST - ppublish -SO - Internist (Berl). 2006 Oct;47(10):1001-4, 1006-8, 1010-2. doi: - 10.1007/s00108-006-1708-6. - -PMID- 23745808 -OWN - NLM -STAT- MEDLINE -DCOM- 20140207 -LR - 20190907 -IS - 1873-4294 (Electronic) -IS - 1568-0266 (Linking) -VI - 13 -IP - 13 -DP - 2013 -TI - MicroRNAs in aortic disease. -PG - 1559-72 -AB - MicroRNAs (miRNAs) are non-coding RNAs of ~22 nucleotides which act as down - regulators of gene expression in the post-transcription level and/or in the - translation level. Several studies have shown that the process of their - maturation is rather crucial for the development of cardiovascular system thus - their regulation (up-,down-) is implicated with many cardiac pathologies. This is - evaluated through their circulating levels which are reliable, stable and the - changes in their serum profiles are representative of tissue alterations serum - levels. Furthermore, they have been shown to participate in cardiovascular - disease pathogenesis including atherosclerosis, coronary artery disease, - myocardial infarction, heart failure cardiac arrhythmias and aortic stenosis. In - the present review, we will first describe i) the process of miRNAs' maturation - ii) their role in the cardiovascular development, iii) their role as biomarkers - of cardiac diseases, iv) the cardiac myo-miR families and the v) their role in - cardiac remodeling and the development of cardiac diseases. Second we will review - the miRNA families that participate in aortic stenosis separated according to its - main pathways (imflammation, fibrosis, calcification). Finally, we will describe - the miRNAs that participate in the development of aortic aneurysm and aortic - dissection according to their serum levels. -FAU - Vavuranakis, Manolis -AU - Vavuranakis M -AD - 1st Dept. of Cardiology, Hippokration Hospital, Medical School, University of - Athens, Greece. vavouran@otenet.gr -FAU - Kariori, Maria -AU - Kariori M -FAU - Vrachatis, Dimitrios -AU - Vrachatis D -FAU - Aznaouridis, Konstantinos -AU - Aznaouridis K -FAU - Siasos, Gerasimos -AU - Siasos G -FAU - Kokkou, Eleni -AU - Kokkou E -FAU - Mazaris, Savvas -AU - Mazaris S -FAU - Moldovan, Carmen -AU - Moldovan C -FAU - Kalogeras, Konstantinos -AU - Kalogeras K -FAU - Tousoulis, Dimitris -AU - Tousoulis D -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Top Med Chem -JT - Current topics in medicinal chemistry -JID - 101119673 -RN - 0 (Biomarkers) -RN - 0 (MicroRNAs) -SB - IM -MH - Aortic Diseases/blood/*metabolism -MH - Biomarkers/blood/metabolism -MH - Humans -MH - MicroRNAs/blood/genetics/*metabolism -EDAT- 2013/06/12 06:00 -MHDA- 2014/02/08 06:00 -CRDT- 2013/06/11 06:00 -PHST- 2013/03/20 00:00 [received] -PHST- 2013/04/29 00:00 [accepted] -PHST- 2013/06/11 06:00 [entrez] -PHST- 2013/06/12 06:00 [pubmed] -PHST- 2014/02/08 06:00 [medline] -AID - CTMC-EPUB-20130531-9 [pii] -AID - 10.2174/15680266113139990105 [doi] -PST - ppublish -SO - Curr Top Med Chem. 2013;13(13):1559-72. doi: 10.2174/15680266113139990105. - -PMID- 23702399 -OWN - NLM -STAT- MEDLINE -DCOM- 20140106 -LR - 20181202 -IS - 1558-4410 (Electronic) -IS - 0889-8529 (Linking) -VI - 42 -IP - 2 -DP - 2013 Jun -TI - Endogenous sex steroid levels and cardiovascular disease in relation to the - menopause: a systematic review. -PG - 227-53 -LID - S0889-8529(13)00013-3 [pii] -LID - 10.1016/j.ecl.2013.02.003 [doi] -AB - Heart disease remains a major cause of death among women in the United States. - This article focuses on physiologic endogenous estrogen levels with a systematic - review of literature related to endogenous sex steroid levels and coronary artery - disease (CAD) among postmenopausal women with natural or surgical menopause. - There is adequate reason to seek evidence for associations of circulating - estrogen levels and CAD. In the future, even if ovarian senescence-associated - hormonal changes are confirmed to be associated with CAD in cohort studies of - postmenopausal women, there may be other components explaining the gender - differences in CAD patterns. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Crandall, Carolyn J -AU - Crandall CJ -AD - Department of Medicine, David Geffen School of Medicine, University of California - at Los Angeles, Los Angeles, CA 90024, USA. ccrandall@mednet.ucla.edu -FAU - Barrett-Connor, Elizabeth -AU - Barrett-Connor E -LA - eng -PT - Journal Article -PT - Review -PT - Systematic Review -DEP - 20130406 -PL - United States -TA - Endocrinol Metab Clin North Am -JT - Endocrinology and metabolism clinics of North America -JID - 8800104 -RN - 0 (Androgens) -RN - 0 (Estrogens) -RN - 0 (Sex Hormone-Binding Globulin) -RN - 4TI98Z838E (Estradiol) -SB - IM -MH - *Aging -MH - Androgens/*blood -MH - Cardiovascular Diseases/blood/epidemiology/etiology/*prevention & control -MH - Estradiol/*blood -MH - Estrogen Replacement Therapy -MH - Estrogens/*blood -MH - Female -MH - *Hormone Replacement Therapy -MH - Humans -MH - Hyperlipidemias/physiopathology/prevention & control -MH - Postmenopause -MH - Risk Factors -MH - Sex Hormone-Binding Globulin/analysis -EDAT- 2013/05/25 06:00 -MHDA- 2014/01/07 06:00 -CRDT- 2013/05/25 06:00 -PHST- 2013/05/25 06:00 [entrez] -PHST- 2013/05/25 06:00 [pubmed] -PHST- 2014/01/07 06:00 [medline] -AID - S0889-8529(13)00013-3 [pii] -AID - 10.1016/j.ecl.2013.02.003 [doi] -PST - ppublish -SO - Endocrinol Metab Clin North Am. 2013 Jun;42(2):227-53. doi: - 10.1016/j.ecl.2013.02.003. Epub 2013 Apr 6. - -PMID- 24053126 -OWN - NLM -STAT- MEDLINE -DCOM- 20150420 -LR - 20211021 -IS - 1557-7716 (Electronic) -IS - 1523-0864 (Print) -IS - 1523-0864 (Linking) -VI - 21 -IP - 8 -DP - 2014 Sep 10 -TI - HypoxamiR regulation and function in ischemic cardiovascular diseases. -PG - 1202-19 -LID - 10.1089/ars.2013.5403 [doi] -AB - SIGNIFICANCE: MicroRNAs (miRNAs) are deregulated and play a causal role in - numerous cardiovascular diseases, including myocardial infarction, coronary - artery disease, hypertension, heart failure, stroke, peripheral artery disease, - kidney ischemia-reperfusion. RECENT ADVANCES: One crucial component of ischemic - cardiovascular diseases is represented by hypoxia. Indeed, hypoxia is a powerful - stimulus regulating the expression of a specific subset of miRNAs, named - hypoxia-induced miRNAs (hypoxamiR). These miRNAs are fundamental regulators of - the cell responses to decreased oxygen tension. Certain hypoxamiRs seem to have a - particularly pervasive role, such as miR-210 that is virtually induced in all - ischemic diseases tested so far. However, its specific function may change - according to the physiopathological context. CRITICAL ISSUES: The discovery of - HypoxamiR dates back 6 years. Thus, despite a rapid growth in knowledge and - attention, a deeper insight of the molecular mechanisms underpinning hypoxamiR - regulation and function is needed. FUTURE DIRECTIONS: An extended understanding - of the function of hypoxamiR in gene regulatory networks associated with - cardiovascular diseases will allow the identification of novel molecular - mechanisms of disease and indicate the development of innovative therapeutic - approaches. -FAU - Greco, Simona -AU - Greco S -AD - 1 Molecular Cardiology Laboratory , IRCCS-Policlinico San Donato, Milan, Italy . -FAU - Gaetano, Carlo -AU - Gaetano C -FAU - Martelli, Fabio -AU - Martelli F -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131112 -PL - United States -TA - Antioxid Redox Signal -JT - Antioxidants & redox signaling -JID - 100888899 -RN - 0 (MicroRNAs) -SB - IM -MH - Animals -MH - Apoptosis -MH - Cardiovascular Diseases/genetics/*metabolism -MH - Humans -MH - Ischemia/genetics/*metabolism -MH - MicroRNAs/*physiology -MH - Neovascularization, Physiologic -MH - Oxidative Stress -MH - RNA Interference -PMC - PMC4142792 -EDAT- 2013/09/24 06:00 -MHDA- 2015/04/22 06:00 -PMCR- 2015/09/10 -CRDT- 2013/09/24 06:00 -PHST- 2013/09/24 06:00 [entrez] -PHST- 2013/09/24 06:00 [pubmed] -PHST- 2015/04/22 06:00 [medline] -PHST- 2015/09/10 00:00 [pmc-release] -AID - 10.1089/ars.2013.5403 [pii] -AID - 10.1089/ars.2013.5403 [doi] -PST - ppublish -SO - Antioxid Redox Signal. 2014 Sep 10;21(8):1202-19. doi: 10.1089/ars.2013.5403. - Epub 2013 Nov 12. - -PMID- 16972538 -OWN - NLM -STAT- MEDLINE -DCOM- 20061109 -LR - 20071115 -IS - 1660-9379 (Print) -IS - 1660-9379 (Linking) -VI - 2 -IP - 76 -DP - 2006 Aug 23 -TI - [Diabetes mellitus and congestive heart failure: physiopathology and treatment]. -PG - 1893-6, 1898-900 -AB - Diabetes mellitus increases by 2.5 to 5 the relative risk of congestive heart - failure. Besides the classical risk factors of congestive heart failure such as - obesity, arterial hypertension and coronary artery disease that are frequently - associated to type 2 diabetes, a diabetic cardiomyopathy plays also a role. This - specific complication is related to metabolic factors and oxidative stress, - leading to muscular cell apoptosis and fibrosis. The management of a diabetic - patient with congestive heart failure has several specificities not only - concerning the treatment of cardiac insufficiency but most importantly concerning - antidiabetic therapy. The relationship between glitazones, peripheral oedema and - risk of congestive heart failure is currently raising much interest and - controversies. -FAU - De Flines, J -AU - De Flines J -AD - Université de Liège Service de diabétologie, nutrition et maladies métaboliques - Département de médecine interne CHU Sart'Tilman B-4000 Liège I. -FAU - Scheen, A J -AU - Scheen AJ -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Diabète sucré et décompensation cardiaque: spécificités ethiopathogéniques et - thérapeutiques. -PL - Switzerland -TA - Rev Med Suisse -JT - Revue medicale suisse -JID - 101219148 -SB - IM -MH - Diabetes Mellitus, Type 2/drug therapy/*physiopathology -MH - Heart Failure/drug therapy/*physiopathology -MH - Humans -MH - Risk Factors -RF - 42 -EDAT- 2006/09/16 09:00 -MHDA- 2006/11/11 09:00 -CRDT- 2006/09/16 09:00 -PHST- 2006/09/16 09:00 [pubmed] -PHST- 2006/11/11 09:00 [medline] -PHST- 2006/09/16 09:00 [entrez] -PST - ppublish -SO - Rev Med Suisse. 2006 Aug 23;2(76):1893-6, 1898-900. - -PMID- 21807282 -OWN - NLM -STAT- MEDLINE -DCOM- 20111201 -LR - 20110802 -IS - 1579-2242 (Electronic) -IS - 0300-8932 (Linking) -VI - 64 Suppl 2 -DP - 2011 Jul -TI - [Fixed-dose compounds and the secondary prevention of ischemic heart disease]. -PG - 3-9 -LID - 10.1016/j.recesp.2011.02.027 [doi] -AB - Worldwide, the leading causes of death are ischemic heart disease and stroke. - Moreover, patients with several risk factors or a history of ischemic heart - disease are at a high risk of coronary event recurrence. There is evidence that - primary cardiovascular disease prevention programs are effective when applied to - the general population. However, therapeutic strategies designed to control - several risk factors simultaneously in patients without evidence of - cardiovascular disease are expensive and difficult to implement. In contrast, - combination drug therapy is commonly used for secondary cardiovascular prevention - and its beneficial effects on morbidity and mortality have been clearly - demonstrated. Nevertheless, the actual impact of this approach is less than might - be expected, partly because of poor adherence to drug regimens and the high cost - of treatment in low- and middle-income countries. In patients who have had an - acute myocardial infarction, the complexity of the regimen is inversely - correlated ith compliance and is, in most cases, the reason for treatment - discontinuation. Moreover, globally the ast majority of cardiovascular events - take place in developing countries with limited health resources here access to - treatment is poor. The development of fixed-dose combinations of drugs (i.e. - polypills) designed for the treatment of myocardial infarction patients could - help overcome these limitations, improve compliance and facilitate the - distribution of and access to treatment in developing countries. We have begun a - large clinical trial in five countries to investigate the beneficial effects of - treatment using a polypill (i.e. aspirin, an angiotensin-converting enzyme - inhibitor and a statin) on ischemic heart disease recurrence. The results of this - study could provide the basis for a new therapeutic approach to the management of - not only cardiovascular disease but also diabetes and stroke. -CI - Copyright © 2011 Sociedad Española de Cardiología. Published by Elsevier Espana. - All rights reserved. -FAU - Fuster, Valentín -AU - Fuster V -AD - Mount Sinai Medical Center, 1 Gustave L. Levy Place, Box 1030, New York, NY - 10029-6574, USA. -FAU - Sanz, Ginés -AU - Sanz G -LA - spa -PT - English Abstract -PT - Journal Article -PT - Review -TT - Compuestos de dosis fija en la prevención secundaria de la cardiopatía isquémica. -PL - Spain -TA - Rev Esp Cardiol -JT - Revista espanola de cardiologia -JID - 0404277 -RN - 0 (Cardiovascular Agents) -RN - 0 (Drug Combinations) -SB - IM -MH - Cardiovascular Agents/*administration & dosage/*therapeutic use -MH - Drug Combinations -MH - Humans -MH - Myocardial Infarction/drug therapy/physiopathology -MH - Myocardial Ischemia/*prevention & control -MH - Secondary Prevention -EDAT- 2011/09/16 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2011/08/03 06:00 -PHST- 2011/02/16 00:00 [received] -PHST- 2011/02/20 00:00 [accepted] -PHST- 2011/08/03 06:00 [entrez] -PHST- 2011/09/16 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -AID - S0300-8932(11)00610-5 [pii] -AID - 10.1016/j.recesp.2011.02.027 [doi] -PST - ppublish -SO - Rev Esp Cardiol. 2011 Jul;64 Suppl 2:3-9. doi: 10.1016/j.recesp.2011.02.027. - -PMID- 16937035 -OWN - NLM -STAT- MEDLINE -DCOM- 20061207 -LR - 20181113 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 11 -IP - 2 -DP - 2006 Jun -TI - Cardiac repair--fact or fancy? -PG - 155-70 -AB - Patients with ischemic cardiomyopathy have a poor prognosis despite all - pharmacological, interventional and surgical treatment modalities currently - applied. Heart transplantation remains the ideal treatment for this group of - patients but the scarcity of donors hinders its widespread application. The - autologous transplantation of stem cells (SCs) for cardiac repair is emerging as - a new therapy for patients with myocardial dysfunction early after an acute - infarction or ischemic cardiomyopathy. The rationale of this novel method is the - enhancement of the repair mechanisms achieved by tissue-specific and circulating - stem/progenitor cells. SCs assist naturally occurring myocardial repair by - contributing to increased myocardial perfusion and contractile performance - especially in the setting of acute myocardial infarction (AMI), but also in - patients with chronic ischemic heart failure and advanced, diffuse coronary - artery disease. The exact mechanism of their action has not been fully - elucidated. Few studies continue to suggest a formation of few new contractile - tissue. The majority if investigators believe that these cells do not persist - long in the myocardium but that they secrete vascular growth and other - cardioprotective factors. -FAU - Leontiadis, E -AU - Leontiadis E -AD - cokkino1@otenet.gr -FAU - Manginas, A -AU - Manginas A -FAU - Cokkinos, D V -AU - Cokkinos DV -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Cytokines) -SB - IM -MH - Cardiomyopathies/pathology/*therapy -MH - Cytokines/*therapeutic use -MH - Humans -MH - Myocardial Ischemia/pathology/*therapy -MH - Randomized Controlled Trials as Topic -MH - Severity of Illness Index -MH - *Stem Cell Transplantation -RF - 130 -EDAT- 2006/08/29 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/08/29 09:00 -PHST- 2006/08/29 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/08/29 09:00 [entrez] -AID - 10.1007/s10741-006-9486-8 [doi] -PST - ppublish -SO - Heart Fail Rev. 2006 Jun;11(2):155-70. doi: 10.1007/s10741-006-9486-8. - -PMID- 19650426 -OWN - NLM -STAT- MEDLINE -DCOM- 20091006 -LR - 20161125 -IS - 1426-9686 (Print) -IS - 1426-9686 (Linking) -VI - 27 -IP - 157 -DP - 2009 Jul -TI - [Complex cardiac rehabilitation in a strategy of secondary prevention of - cardiovascular disease]. -PG - 30-5 -AB - Due to the frequency of occurrence of cardiovascular disease and its course full - of severe complications, patients with this condition make a special population. - This group is the addressee of the preventive actions included in secondary - prevention. The goal of these actions is a reduction of frequency of the - occurrence of consecutive incidents connected with ischemic heart disease, - ischemic stroke and peripheral artery disease. The actions put a special emphasis - on the counteraction of significant and negative from the social-economic point - of view phenomenon, such as disability and premature deaths. The key role within - the frames of the integrated preventive procedure in the patients with - cardiovascular disease plays the modification of physical activity, mainly - realized as a part of a supervised physical training. The training is a basic - element of a systematized cardiac rehabilitation. It was Hellerstain, who as a - pioneer in using this kind of rehabilitation in the patients after acute coronary - incidents, and in the 1950s began propagating a multi-disciplinary attitude to - the cardiac rehabilitation programs. Since WHO's formulation of the first - definition of cardiac rehabilitation in 1964, as a result of the achievements of - modern invasive cardiology, cardiosurgery and pharmacotherapy, the procedures of - treatment of the patients with acute coronary syndrome changed radically. - Moreover, a time of their hospitalization has shortened significantly. This fact - had an influence on created by many scientific associations the successive - development of the standardized process of convalescence, which is cardiac - rehabilitation. The Board of Polish Society of Cardiology (PTK), appreciating the - rank of the issue, appointed a group of experts to work on the standards of the - cardiac rehabilitation, which were published in 2004 in the journal "Folia - Cardiologica". Based on the modified in 2003 requirements established by The - Working Group of Rehabilitation and Effort Physiology of European Society of - Cardiology and the authors' own experiences, they standardize the regulations of - the cardiac rehabilitation. What is specially underlined in this document is - keeping the regulation of cardiac rehabilitation effects optimization with - maximum safety for the patients and recommending wide, not depending on age, - access to complex rehabilitation programs, which contains multi-factor - interventive actions. Promoting all aspects of the improvement of physical - activity, the cardiac rehabilitation programs contribute to the large extent to - the positive modification of arthrosclerosis risk factors, the improvement of - physical performance and reducing the risk of occurrence of next acute - cardiovascular incidences. All the above-mentioned aspects lead to a comeback to - active participation in the social life, and consequently have a positive - influence on the quality of life of the people with cardiovascular disease. The - aim of this work is summing up the present knowledge of cardiac rehabilitation as - a basic element of secondary prevention. -FAU - Kałka, Dariusz -AU - Kałka D -AD - Akademia Medyczna, Wrocław, Zakład Elektrokardiologii i Prewencji Chorób - Sercowo-Naczyniowych, Katedra Patofizjologii. dariusz.kalka@interia.pl -FAU - Sobieszczańska, Małgorzata -AU - Sobieszczańska M -FAU - Pilecki, Witold -AU - Pilecki W -FAU - Adamus, Jerzy -AU - Adamus J -LA - pol -PT - Journal Article -PT - Review -TT - Kompleksowa rehabilitacja kardiologiczna w strategii prewencji wtórnej choroby - sercowo-naczyniowej. -PL - Poland -TA - Pol Merkur Lekarski -JT - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego -JID - 9705469 -SB - IM -MH - *Cardiac Rehabilitation -MH - Cardiovascular Diseases/*prevention & control -MH - Exercise -MH - Humans -MH - Life Style -MH - *Quality of Life -MH - Secondary Prevention/*methods -MH - Social Facilitation -RF - 42 -EDAT- 2009/08/05 09:00 -MHDA- 2009/10/07 06:00 -CRDT- 2009/08/05 09:00 -PHST- 2009/08/05 09:00 [entrez] -PHST- 2009/08/05 09:00 [pubmed] -PHST- 2009/10/07 06:00 [medline] -PST - ppublish -SO - Pol Merkur Lekarski. 2009 Jul;27(157):30-5. - -PMID- 17011375 -OWN - NLM -STAT- MEDLINE -DCOM- 20061019 -LR - 20220408 -IS - 1527-9995 (Electronic) -IS - 0090-4295 (Linking) -VI - 68 -IP - 3 Suppl -DP - 2006 Sep -TI - Cardiovascular safety of sildenafil citrate (Viagra): an updated perspective. -PG - 47-60 -AB - Sildenafil citrate (Viagra; Pfizer Inc, New York, NY) relaxes vascular smooth - muscle, resulting in modest reductions in blood pressure that are insufficient to - stimulate a reflex increase in heart rate. These blood pressure reductions are - similar for healthy men and men with coronary artery disease (CAD) or who use - antihypertensive drugs. Sildenafil does not affect the force of cardiac - contraction, and cardiac performance is unaffected. Sildenafil is mildly - vasodilating in the coronary circulation and does not increase the risk of - ventricular arrhythmia. During exercise and recovery, sildenafil does not cause - clinically significant alterations in hemodynamic parameters in men with CAD, and - it has no negative effects on coronary oxygen consumption, ischemia, or exercise - capacity. Clinical trial data from >13,000 patients, 7 years of international - postmarketing data, and observational studies of >28,000 men in the United - Kingdom and 3813 men in the European Union reveal that (1) there are no special - cardiovascular concerns when sildenafil is used in accordance with product - labeling and (2) the risk for serious events such as myocardial infarction or - death is not increased. However, because safety has not been established in - patients with recent serious cardiovascular events, hypotension or uncontrolled - hypertension, or retinitis pigmentosa, physicians should consult their current - local prescribing information before prescribing sildenafil for these patients. - Among men with erectile dysfunction treated with sildenafil, the adverse event - profile is similar overall to that in men with comorbid cardiovascular disease - (CVD), it is similar between those with and without CAD, and it is similar - between those who take and those who do not take antihypertensive drugs - (regardless of the number or class). In a controlled interaction study of - sildenafil and amlodipine, the mean additional reduction in supine blood pressure - was 8 mm Hg systolic and 7 mm Hg diastolic. Sildenafil should be used with - caution in patients who take alpha-blockers because coadministration may lead to - symptomatic hypotension in some individuals. When sildenafil is coadministered - with an alpha-blocker, patients should be stable on alpha-blocker therapy before - initiating sildenafil treatment and sildenafil should be initiated at the lowest - dose. Also, in the absence of information specific to mixed alpha/beta blockers, - such as carvedilol and labetalol, similar care should be taken as for - alpha-blockers. Sildenafil potentiates the hypotensive effects of nitrates, and - its administration to patients who are using organic nitrates in any form, either - regularly or intermittently, is contraindicated. Before prescribing sildenafil, - physicians should carefully consider whether their patients with underlying CVD - could be affected adversely by resuming sexual activity. Management - recommendations based on cardiovascular risk, from the Second Princeton Consensus - Conference, are presented. -FAU - Jackson, Graham -AU - Jackson G -AD - St. Thomas Hospital, London, United Kingdom. gjcardiol@talk21.com -FAU - Montorsi, Piero -AU - Montorsi P -FAU - Cheitlin, Melvin D -AU - Cheitlin MD -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Urology -JT - Urology -JID - 0366151 -RN - 0 (Phosphodiesterase Inhibitors) -RN - 0 (Piperazines) -RN - 0 (Purines) -RN - 0 (Sulfones) -RN - BW9B0ZE037 (Sildenafil Citrate) -SB - IM -MH - Cardiovascular Diseases/complications -MH - Cardiovascular Physiological Phenomena/*drug effects -MH - Cardiovascular System/*drug effects -MH - Erectile Dysfunction/complications/*drug therapy -MH - Humans -MH - Male -MH - Phosphodiesterase Inhibitors/adverse effects/*pharmacology/*therapeutic use -MH - Piperazines/adverse effects/*pharmacology/*therapeutic use -MH - Purines -MH - Sildenafil Citrate -MH - Sulfones -RF - 52 -EDAT- 2006/10/03 09:00 -MHDA- 2006/10/20 09:00 -CRDT- 2006/10/03 09:00 -PHST- 2006/02/06 00:00 [received] -PHST- 2006/04/25 00:00 [revised] -PHST- 2006/05/22 00:00 [accepted] -PHST- 2006/10/03 09:00 [pubmed] -PHST- 2006/10/20 09:00 [medline] -PHST- 2006/10/03 09:00 [entrez] -AID - S0090-4295(06)00891-0 [pii] -AID - 10.1016/j.urology.2006.05.047 [doi] -PST - ppublish -SO - Urology. 2006 Sep;68(3 Suppl):47-60. doi: 10.1016/j.urology.2006.05.047. - -PMID- 23174917 -OWN - NLM -STAT- MEDLINE -DCOM- 20131209 -LR - 20130307 -IS - 1827-1596 (Electronic) -IS - 0375-9393 (Linking) -VI - 79 -IP - 3 -DP - 2013 Mar -TI - End-organ protection in cardiac surgery. -PG - 285-93 -AB - Mortality and morbidity postcardiac surgery with cardiopulmonary bypass (CPB) - remain relative stable over the last decades, while the number of patients with - increased comorbidity and more complex cardiac disease increases. Nevertheless, - end-organ dysfunction and/or failure remain an issue. Multiple perioperative - variables, such as non-optimal oxygen delivery, manipulation of the aorta, - hyperlactatemia, type of anesthesia, surgical procedure and myocardial protection - can be hold responsible for end-organ failure postcardiac surgery. However, it - becomes more and more evident that also pre-existing factors, such as metabolic - syndrome, renal insufficiency, hypertension, stroke and infection exacerbate - mortality and morbidity. Unfortunately, these predisposing risk factors cannot be - influenced perioperatively. Therefore, therapy should focus on controlling - perioperative variables that, in combination with the predisposing factors, will - further exacerbate organ dysfunction. In order to achieve this, more emphasis - should be given to a patient-specific, goal-directed perfusion approach. This - review will mainly focus on the impact of perioperative variables. -FAU - De Somer, F -AU - De Somer F -AD - Heart Centre, University Hospital Ghent, Ghent, Belgium. Filip.DeSomer@UGent.be -LA - eng -PT - Journal Article -PT - Review -DEP - 20121122 -PL - Italy -TA - Minerva Anestesiol -JT - Minerva anestesiologica -JID - 0375272 -SB - IM -MH - Cardiac Surgical Procedures/*methods -MH - Coronary Circulation -MH - Embolism/therapy -MH - Embolism, Air/therapy -MH - Heart Diseases/complications/drug therapy/physiopathology/surgery -MH - Hemodilution -MH - Humans -MH - Oxygen Inhalation Therapy -MH - Systemic Inflammatory Response Syndrome/physiopathology/therapy -EDAT- 2012/11/24 06:00 -MHDA- 2013/12/16 06:00 -CRDT- 2012/11/24 06:00 -PHST- 2012/11/24 06:00 [entrez] -PHST- 2012/11/24 06:00 [pubmed] -PHST- 2013/12/16 06:00 [medline] -AID - R02128055 [pii] -PST - ppublish -SO - Minerva Anestesiol. 2013 Mar;79(3):285-93. Epub 2012 Nov 22. - -PMID- 19032583 -OWN - NLM -STAT- MEDLINE -DCOM- 20090410 -LR - 20250529 -IS - 1530-0277 (Electronic) -IS - 0145-6008 (Print) -IS - 0145-6008 (Linking) -VI - 33 -IP - 2 -DP - 2009 Feb -TI - Alcohol in moderation, cardioprotection, and neuroprotection: epidemiological - considerations and mechanistic studies. -PG - 206-19 -LID - 10.1111/j.1530-0277.2008.00828.x [doi] -AB - In contrast to many years of important research and clinical attention to the - pathological effects of alcohol (ethanol) abuse, the past several decades have - seen the publication of a number of peer-reviewed studies indicating the - beneficial effects of light-moderate, nonbinge consumption of varied alcoholic - beverages, as well as experimental demonstrations that moderate alcohol exposure - can initiate typically cytoprotective mechanisms. A considerable body of - epidemiology associates moderate alcohol consumption with significantly reduced - risks of coronary heart disease and, albeit currently a less robust relationship, - cerebrovascular (ischemic) stroke. Experimental studies with experimental rodent - models and cultures (cardiac myocytes, endothelial cells) indicate that moderate - alcohol exposure can promote anti-inflammatory processes involving adenosine - receptors, protein kinase C (PKC), nitric oxide synthase, heat shock proteins, - and others which could underlie cardioprotection. Also, brain functional - comparisons between older moderate alcohol consumers and nondrinkers have - received more recent epidemiological study. In over half of nearly 45 reports - since the early 1990s, significantly reduced risks of cognitive loss or dementia - in moderate, nonbinge consumers of alcohol (wine, beer, liquor) have been - observed, whereas increased risk has been seen only in a few studies. - Physiological explanations for the apparent CNS benefits of moderate consumption - have invoked alcohol's cardiovascular and/or hematological effects, but there is - also experimental evidence that moderate alcohol levels can exert direct - "neuroprotective" actions-pertinent are several studies in vivo and rat brain - organotypic cultures, in which antecedent or preconditioning exposure to moderate - alcohol neuroprotects against ischemia, endotoxin, beta-amyloid, a toxic protein - intimately associated with Alzheimer's, or gp120, the neuroinflammatory HIV-1 - envelope protein. The alcohol-dependent neuroprotected state appears linked to - activation of signal transduction processes potentially involving reactive oxygen - species, several key protein kinases, and increased heat shock proteins. Thus to - a certain extent, moderate alcohol exposure appears to trigger analogous mild - stress-associated, anti-inflammatory mechanisms in the heart, vasculature, and - brain that tend to promote cellular survival pathways. -FAU - Collins, Michael A -AU - Collins MA -AD - Department of Cell Biology, Neurobiology & Anatomy, Loyola University Chicago - Stritch School of Medicine, 2160 S. 1st Avenue, Maywood, IL 60153, USA. - mcollin@lumc.edu -FAU - Neafsey, Edward J -AU - Neafsey EJ -FAU - Mukamal, Kenneth J -AU - Mukamal KJ -FAU - Gray, Mary O -AU - Gray MO -FAU - Parks, Dale A -AU - Parks DA -FAU - Das, Dipak K -AU - Das DK -FAU - Korthuis, Ronald J -AU - Korthuis RJ -LA - eng -GR - AA 014945/AA/NIAAA NIH HHS/United States -GR - AA 11135/AA/NIAAA NIH HHS/United States -GR - AA 13361/AA/NIAAA NIH HHS/United States -GR - F31 AA013361/AA/NIAAA NIH HHS/United States -GR - R01 AA013568/AA/NIAAA NIH HHS/United States -GR - R01 AA014945/AA/NIAAA NIH HHS/United States -GR - P01 DK043785/DK/NIDDK NIH HHS/United States -GR - R01 AA011135/AA/NIAAA NIH HHS/United States -GR - AA 011723/AA/NIAAA NIH HHS/United States -GR - AA 013568/AA/NIAAA NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20081119 -PL - England -TA - Alcohol Clin Exp Res -JT - Alcoholism, clinical and experimental research -JID - 7707242 -RN - 0 (Antioxidants) -RN - 0 (Cardiotonic Agents) -RN - 0 (Central Nervous System Depressants) -RN - 0 (Neuroprotective Agents) -RN - 0 (Stilbenes) -RN - 31C4KY9ESH (Nitric Oxide) -RN - 3K9958V90M (Ethanol) -RN - EC 2.7.11.13 (Protein Kinase C) -RN - Q369O8926L (Resveratrol) -SB - IM -MH - Alcohol Drinking/*epidemiology/metabolism/*physiopathology -MH - Animals -MH - Antioxidants/pharmacology -MH - *Cardiotonic Agents -MH - Cardiovascular Diseases/epidemiology/prevention & control -MH - Central Nervous System Depressants/*pharmacology -MH - Dementia/epidemiology/prevention & control -MH - Ethanol/*pharmacology -MH - Humans -MH - *Neuroprotective Agents -MH - Nitric Oxide/physiology -MH - Protein Kinase C/metabolism -MH - Resveratrol -MH - Stilbenes/pharmacology -PMC - PMC2908373 -MID - NIHMS84828 -EDAT- 2008/11/27 09:00 -MHDA- 2009/04/11 09:00 -PMCR- 2010/07/22 -CRDT- 2008/11/27 09:00 -PHST- 2008/11/27 09:00 [pubmed] -PHST- 2009/04/11 09:00 [medline] -PHST- 2008/11/27 09:00 [entrez] -PHST- 2010/07/22 00:00 [pmc-release] -AID - ACER828 [pii] -AID - 10.1111/j.1530-0277.2008.00828.x [doi] -PST - ppublish -SO - Alcohol Clin Exp Res. 2009 Feb;33(2):206-19. doi: - 10.1111/j.1530-0277.2008.00828.x. Epub 2008 Nov 19. - -PMID- 22204436 -OWN - NLM -STAT- MEDLINE -DCOM- 20120522 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 17 -IP - 38 -DP - 2011 Dec -TI - Pleiotropic effects of glucagon-like peptide-1 (GLP-1)-based therapies on - vascular complications in diabetes. -PG - 4379-85 -AB - Accelerated atherosclerosis and microvascular complications are the leading - causes of coronary heart disease, end-stage renal failure, acquired blindness and - a variety of neuropathies, which could account for disabilities and high - mortality rates in patients with diabetes. Glucagon-like peptide-1 (GLP-1) - belongs to the incretin hormone family. L cells in the small intestine secrete - GLP-1 in response to food intake. GLP-1 not only enhances glucose-evoked insulin - release from pancreatic β-cells, but also suppresses glucagon secretion from - pancreatic α-cells. In addition, GLP-1 slows gastric emptying. Therefore, - enhancement of GLP-1 secretion is a potential therapeutic target for the - treatment of type 2 diabetes. Dipeptidyl peptidase-4 (DPP-4) is a responsible - enzyme that mainly degrades GLP-1, and the half-life of circulating GLP-1 is very - short. Recently, DPP-4 inhibitors and DPP-4-resistant GLP-1 receptor (GLP-1R) - agonists have been developed and clinically used for the treatment of type 2 - diabetes as a GLP-1-based medicine. GLP-1R is shown to exist in extra-pancreatic - tissues such as vessels, kidney and heart, and could mediate the diverse - biological actions of GLP-1 in a variety of tissues. So, in this paper, we review - the pleiotropic effects of GLP-1-based therapies and its clinical utility in - vascular complications in diabetes. -FAU - Yamagishi, Sho-ichi -AU - Yamagishi S -AD - Department of Pathophysiology and Therapeutics of Diabetic Vascular - Complications, Kurume University School of Medicine, Kurume, Japan. - shoichi@med.kurume-u.ac.jp -FAU - Matsui, Takanori -AU - Matsui T -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Dipeptidyl-Peptidase IV Inhibitors) -RN - 0 (GLP1R protein, human) -RN - 0 (Glucagon-Like Peptide-1 Receptor) -RN - 0 (Insulin) -RN - 0 (Receptors, Glucagon) -RN - 89750-14-1 (Glucagon-Like Peptide 1) -RN - 9007-92-5 (Glucagon) -RN - EC 3.4.14.5 (Dipeptidyl Peptidase 4) -SB - IM -MH - Animals -MH - Diabetes Mellitus, Type 2/complications/*drug therapy/metabolism -MH - Diabetic Angiopathies/*drug therapy/etiology/metabolism -MH - Diabetic Nephropathies/drug therapy/etiology/metabolism -MH - Diabetic Neuropathies/drug therapy/etiology/metabolism -MH - Diabetic Retinopathy/drug therapy/etiology/metabolism -MH - Dipeptidyl Peptidase 4/metabolism -MH - Dipeptidyl-Peptidase IV Inhibitors/*therapeutic use -MH - Glucagon/metabolism -MH - Glucagon-Like Peptide 1/*metabolism -MH - Glucagon-Like Peptide-1 Receptor -MH - Humans -MH - Insulin/metabolism -MH - Insulin Secretion -MH - Insulin-Secreting Cells/drug effects/metabolism -MH - Receptors, Glucagon/*agonists -EDAT- 2011/12/30 06:00 -MHDA- 2012/05/23 06:00 -CRDT- 2011/12/30 06:00 -PHST- 2011/10/13 00:00 [received] -PHST- 2011/10/31 00:00 [accepted] -PHST- 2011/12/30 06:00 [entrez] -PHST- 2011/12/30 06:00 [pubmed] -PHST- 2012/05/23 06:00 [medline] -AID - BSP/CPD/E-PUB/ 000796 [pii] -AID - 10.2174/138161211798999456 [doi] -PST - ppublish -SO - Curr Pharm Des. 2011 Dec;17(38):4379-85. doi: 10.2174/138161211798999456. - -PMID- 23470076 -OWN - NLM -STAT- MEDLINE -DCOM- 20130920 -LR - 20230126 -IS - 1873-4294 (Electronic) -IS - 1568-0266 (Linking) -VI - 13 -IP - 2 -DP - 2013 -TI - Cystatin C: an emerging biomarker in cardiovascular disease. -PG - 164-79 -AB - Cystatin C (cys-C) is a small protein molecule (120 amino acid peptide chain, - approximately 13kDa) produced by virtually all nucleated cells in the human body. - It belongs to the family of papain-like cysteine proteases and its main - biological role is the extracellular inhibition of cathepsins. It's near constant - production rate, the fact that it is freely filtered from the glomerular membrane - and then completely reabsorbed without being secreted from the proximal tubular - cells, made it an almost perfect candidate for estimating renal function. The - strong correlation between chronic kidney disease (CKD) and cardiovascular - disease (CVD) along with the growing understanding of the role of cysteinyl - cathepsins in the pathophysiology of CVD inspired researchers to explore the - potential association of cys-C with CVD. Throughout the spectrum of CVD - (peripheral arterial disease, stroke, abdominal aortic aneurysm, heart failure, - coronary artery disease) adverse outcomes and risk stratification have been - associated with high plasma levels of cys-C. The exact mechanisms behind the - observed correlations have not been comprehensively clarified. Plausible links - between high cys-C levels and poor cardiovascular outcome could be impaired renal - function, atherogenesis and inflammatory mediators, remodeling of myocardial - tissue and others (genetic factors, aging and social habits). The scope of the - present article is to systematically review the current knowledge about cys-C - biochemistry, metabolism, methods of detection and quantification and - pathophysiological associations with different aspects of CVD. -FAU - Angelidis, Christos -AU - Angelidis C -AD - Cardiology Department and Cardiac Catheterization Laboratory, Athens General - Hospital G. Gennimatas, Athens, Greece. cangelidis@gmail.com -FAU - Deftereos, Spyridon -AU - Deftereos S -FAU - Giannopoulos, Georgios -AU - Giannopoulos G -FAU - Anatoliotakis, Nikolaos -AU - Anatoliotakis N -FAU - Bouras, Georgios -AU - Bouras G -FAU - Hatzis, Georgios -AU - Hatzis G -FAU - Panagopoulou, Vasiliki -AU - Panagopoulou V -FAU - Pyrgakis, Vlasios -AU - Pyrgakis V -FAU - Cleman, Michael W -AU - Cleman MW -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Top Med Chem -JT - Current topics in medicinal chemistry -JID - 101119673 -RN - 0 (Biomarkers) -RN - 0 (Cystatin C) -RN - EC 3.4.- (Cathepsins) -SB - IM -MH - Amino Acid Sequence -MH - Animals -MH - Aortic Aneurysm, Abdominal/metabolism -MH - Biomarkers/*blood -MH - Cardiovascular Diseases/diagnosis/etiology/*metabolism/*physiopathology -MH - Cathepsins/metabolism -MH - Cystatin C/*blood/chemistry/metabolism -MH - Heart Failure/metabolism/physiopathology -MH - Humans -MH - Kidney/metabolism -MH - Molecular Sequence Data -MH - Peripheral Arterial Disease/metabolism/physiopathology -MH - Predictive Value of Tests -MH - Renal Insufficiency, Chronic/complications/metabolism -MH - Stroke/metabolism -EDAT- 2013/03/09 06:00 -MHDA- 2013/09/21 06:00 -CRDT- 2013/03/09 06:00 -PHST- 2012/12/01 00:00 [received] -PHST- 2013/01/08 00:00 [revised] -PHST- 2013/01/24 00:00 [accepted] -PHST- 2013/03/09 06:00 [entrez] -PHST- 2013/03/09 06:00 [pubmed] -PHST- 2013/09/21 06:00 [medline] -AID - CTMC-EPUB-20130304-6 [pii] -AID - 10.2174/1568026611313020006 [doi] -PST - ppublish -SO - Curr Top Med Chem. 2013;13(2):164-79. doi: 10.2174/1568026611313020006. - -PMID- 19359992 -OWN - NLM -STAT- MEDLINE -DCOM- 20090818 -LR - 20141120 -IS - 1365-2346 (Electronic) -IS - 0265-0215 (Linking) -VI - 26 -IP - 6 -DP - 2009 Jun -TI - Preoperative cardiovascular assessment in noncardiac surgery: an update. -PG - 449-57 -LID - 10.1097/EJA.0b013e3283297512 [doi] -AB - Cardiac complications are a major cause of perioperative morbidity and mortality. - These are caused by either myocardial ischaemia or acute coronary thrombosis. The - preoperative assessment aims to collect information on the extent and the - stability of the cardiovascular disease in order to predict the patient's risk - for developing perioperative cardiac complications. This assessment allows - measures to be taken that aim to reduce such risks. The present review summarizes - the current state of knowledge on the preoperative assessment of the cardiac - patient scheduled for noncardiac surgery. -FAU - De Hert, Stefan G -AU - De Hert SG -AD - Department of Anesthesiology, Division of Cardiothoracic and Vascular - Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, The - Netherlands. s.g.dehert@amc.uva.nl -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Eur J Anaesthesiol -JT - European journal of anaesthesiology -JID - 8411711 -SB - IM -MH - Clinical Protocols -MH - Death -MH - Elective Surgical Procedures -MH - Emergency Treatment -MH - Exercise Test -MH - Guidelines as Topic/standards -MH - *Heart Diseases/diagnosis/therapy -MH - Humans -MH - Intraoperative Complications/*prevention & control -MH - Monitoring, Physiologic/methods -MH - Myocardial Infarction/complications/therapy -MH - Myocardial Revascularization -MH - Preoperative Care/*methods -MH - Risk Assessment -MH - *Surgical Procedures, Operative/adverse effects -RF - 62 -EDAT- 2009/04/11 09:00 -MHDA- 2009/08/19 09:00 -CRDT- 2009/04/11 09:00 -PHST- 2009/04/11 09:00 [entrez] -PHST- 2009/04/11 09:00 [pubmed] -PHST- 2009/08/19 09:00 [medline] -AID - 10.1097/EJA.0b013e3283297512 [doi] -PST - ppublish -SO - Eur J Anaesthesiol. 2009 Jun;26(6):449-57. doi: 10.1097/EJA.0b013e3283297512. - -PMID- 23680887 -OWN - NLM -STAT- MEDLINE -DCOM- 20140131 -LR - 20220410 -IS - 1468-201X (Electronic) -IS - 1355-6037 (Linking) -VI - 99 -IP - 18 -DP - 2013 Sep -TI - Recent advances in the epidemiology, pathogenesis and prognosis of acute heart - failure and cardiomyopathy in Africa. -PG - 1317-22 -LID - 10.1136/heartjnl-2013-303592 [doi] -AB - This review addresses recent advances in the epidemiology, pathogenesis and - prognosis of acute heart failure and cardiomyopathy based on research conducted - in Africa. We searched Medline/PubMed for publications on acute decompensated - heart failure and cardiomyopathy in Africa for the past 5 years (ie, 1 January - 2008 to 31 December 2012). This was supplemented with personal communications - with colleagues from Africa working in the field. A large prospective registry - has shown that acute decompensated heart failure is caused by hypertension, - cardiomyopathy and rheumatic heart disease in 90% of cases, a pattern that is in - contrast with the dominance of coronary artery disease in North America and - Europe. Furthermore, acute heart failure is a disease of the young with a mean - age of 52 years, occurs equally in men and women, and is associated with high - mortality at 6 months (∼18%), which is, however, similar to that observed in - non-African heart failure registries, suggesting that heart failure has a dire - prognosis globally, regardless of aetiology. The molecular genetics of dilated - cardiomyopathy, hypertrophic cardiomyopathy and arrhythmogenic right ventricular - cardiomyopathy in Africans is consistent with observations elsewhere in the - world; the unique founder effects in the Afrikaner provide an opportunity for the - study of genotype-phenotype correlations in large numbers of individuals with - cardiomyopathy due to the same mutation. Advances in the understanding of the - molecular mechanisms of peripartum cardiomyopathy have led to promising clinical - trials of bromocriptine in the treatment of peripartum heart failure. The key - challenges of management of heart failure are the urgent need to increase the use - of proven treatments by physicians, and the control of hypertension in primary - care and at the population level. -FAU - Sliwa, Karen -AU - Sliwa K -AD - Hatter Institute for Cardiovascular Research in Africa, Department of Medicine, - Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa. -FAU - Mayosi, Bongani M -AU - Mayosi BM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130516 -PL - England -TA - Heart -JT - Heart (British Cardiac Society) -JID - 9602087 -SB - IM -MH - Africa/epidemiology -MH - Cardiomyopathies/*epidemiology/physiopathology/prevention & control -MH - Endothelium, Vascular -MH - Female -MH - Global Health -MH - Heart Failure/*epidemiology/physiopathology/prevention & control -MH - Humans -MH - Hypertension/epidemiology -MH - Male -MH - Prognosis -MH - Registries -OTO - NOTNLM -OT - HEART FAILURE -EDAT- 2013/05/18 06:00 -MHDA- 2014/02/01 06:00 -CRDT- 2013/05/18 06:00 -PHST- 2013/05/18 06:00 [entrez] -PHST- 2013/05/18 06:00 [pubmed] -PHST- 2014/02/01 06:00 [medline] -AID - heartjnl-2013-303592 [pii] -AID - 10.1136/heartjnl-2013-303592 [doi] -PST - ppublish -SO - Heart. 2013 Sep;99(18):1317-22. doi: 10.1136/heartjnl-2013-303592. Epub 2013 May - 16. - -PMID- 17369996 -OWN - NLM -STAT- MEDLINE -DCOM- 20070904 -LR - 20180604 -IS - 1537-744X (Electronic) -IS - 2356-6140 (Print) -IS - 1537-744X (Linking) -VI - 6 -DP - 2006 Feb 2 -TI - Clinical holistic medicine: the Dean Ornish program ("opening the heart") in - cardiovascular disease. -PG - 1977-84 -AB - Dean Ornish of the Preventive Medicine Research Institute in Sausalito, - California has created an intensive holistic treatment for coronary heart - patients with improved diet (low fat, whole foods, plant based), exercise, stress - management, and social support that has proven to be efficient. In this paper, we - analyze the rationale behind his cure in relation to contemporary holistic - medical theory. In spite of a complex treatment program, the principles seem to - be simple and in accordance with holistic medical theories, like the Antonovsky - concept of rehabilitating the sense of coherence and the life mission theory for - holistic medicine. We believe there is a need for the allocation of resources for - further research into the aspects of holistic health and its methods, where - positive and significant results have been proven and reproduced at several - sites. -FAU - Ventegodt, Søren -AU - Ventegodt S -AD - Nordic School of Holistic Medicine and Quality of Life Research Center, - Copenhagen K, Denmark. ventegodt@livskvalitet.org -FAU - Merrick, Efrat -AU - Merrick E -FAU - Merrick, Joav -AU - Merrick J -LA - eng -PT - Case Reports -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20060202 -PL - United States -TA - ScientificWorldJournal -JT - TheScientificWorldJournal -JID - 101131163 -SB - IM -MH - Adult -MH - Cardiovascular Diseases/physiopathology/*psychology/*therapy -MH - Clinical Medicine/*methods -MH - Heart/physiology -MH - *Holistic Health -MH - Humans -MH - Male -MH - Middle Aged -MH - Quality of Life/psychology -PMC - PMC5917159 -EDAT- 2007/03/21 09:00 -MHDA- 2007/09/05 09:00 -PMCR- 2006/02/02 -CRDT- 2007/03/21 09:00 -PHST- 2007/03/21 09:00 [pubmed] -PHST- 2007/09/05 09:00 [medline] -PHST- 2007/03/21 09:00 [entrez] -PHST- 2006/02/02 00:00 [pmc-release] -AID - 704606 [pii] -AID - 10.1100/tsw.2006.330 [doi] -PST - epublish -SO - ScientificWorldJournal. 2006 Feb 2;6:1977-84. doi: 10.1100/tsw.2006.330. - -PMID- 19364331 -OWN - NLM -STAT- MEDLINE -DCOM- 20090731 -LR - 20220317 -IS - 1470-8736 (Electronic) -IS - 0143-5221 (Print) -IS - 0143-5221 (Linking) -VI - 116 -IP - 10 -DP - 2009 May -TI - Diabetic cardiomyopathy. -PG - 741-60 -LID - 10.1042/CS20080500 [doi] -AB - Diabetic cardiomyopathy is a distinct primary disease process, independent of - coronary artery disease, which leads to heart failure in diabetic patients. - Epidemiological and clinical trial data have confirmed the greater incidence and - prevalence of heart failure in diabetes. Novel echocardiographic and MR (magnetic - resonance) techniques have enabled a more accurate means of phenotyping diabetic - cardiomyopathy. Experimental models of diabetes have provided a range of novel - molecular targets for this condition, but none have been substantiated in humans. - Similarly, although ultrastructural pathology of the microvessels and - cardiomyocytes is well described in animal models, studies in humans are small - and limited to light microscopy. With regard to treatment, recent data with - thiazolidinediones has generated much controversy in terms of the cardiac safety - of both these and other drugs currently in use and under development. Clinical - trials are urgently required to establish the efficacy of currently available - agents for heart failure, as well as novel therapies in patients specifically - with diabetic cardiomyopathy. -FAU - Asghar, Omar -AU - Asghar O -AD - The Manchester Heart Centre, Manchester Royal Infirmary, Manchester M13 9WL, UK. -FAU - Al-Sunni, Ahmed -AU - Al-Sunni A -FAU - Khavandi, Kaivan -AU - Khavandi K -FAU - Khavandi, Ali -AU - Khavandi A -FAU - Withers, Sarah -AU - Withers S -FAU - Greenstein, Adam -AU - Greenstein A -FAU - Heagerty, Anthony M -AU - Heagerty AM -FAU - Malik, Rayaz A -AU - Malik RA -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Clin Sci (Lond) -JT - Clinical science (London, England : 1979) -JID - 7905731 -RN - 0 (Biomarkers) -RN - 0 (Hypoglycemic Agents) -SB - IM -MH - Biomarkers/metabolism -MH - *Cardiomyopathies/diagnosis/etiology/therapy -MH - *Diabetes Mellitus, Type 2/diagnosis/etiology/therapy -MH - *Diabetic Angiopathies/diagnosis/etiology/therapy -MH - Heart Failure/etiology -MH - Humans -MH - Hyperglycemia/*complications -MH - Hypoglycemic Agents/therapeutic use -MH - Microcirculation -MH - Oxidative Stress -MH - Risk Factors -PMC - PMC2782307 -EDAT- 2009/04/15 09:00 -MHDA- 2009/08/01 09:00 -PMCR- 2009/04/15 -CRDT- 2009/04/15 09:00 -PHST- 2009/04/15 09:00 [entrez] -PHST- 2009/04/15 09:00 [pubmed] -PHST- 2009/08/01 09:00 [medline] -PHST- 2009/04/15 00:00 [pmc-release] -AID - CS20080500 [pii] -AID - cs1160741 [pii] -AID - 10.1042/CS20080500 [doi] -PST - ppublish -SO - Clin Sci (Lond). 2009 May;116(10):741-60. doi: 10.1042/CS20080500. - -PMID- 22729032 -OWN - NLM -STAT- MEDLINE -DCOM- 20140702 -LR - 20211021 -IS - 1878-4216 (Electronic) -IS - 0278-5846 (Print) -IS - 0278-5846 (Linking) -VI - 47 -DP - 2013 Dec 2 -TI - Anesthesia, surgery, illness and Alzheimer's disease. -PG - 162-6 -LID - S0278-5846(12)00146-7 [pii] -LID - 10.1016/j.pnpbp.2012.06.011 [doi] -AB - Patients and their families have, for many decades, detected subtle changes in - cognition subsequent to surgery, and only recently has this been subjected to - scientific scrutiny. Through a combination of retrospective human studies, small - prospective biomarker studies, and experiments in animals, it is now clear that - durable consequences of both anesthesia and surgery occur, and that these - intersect with the normal processes of aging, and the abnormal processes of - chronic neurodegeneration. It is highly likely that inflammatory cascades are at - the heart of this intersection, and if confirmed, this suggests a therapeutic - strategy to mitigate enhanced neuropathology in vulnerable surgical patients. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Eckenhoff, Roderic G -AU - Eckenhoff RG -AD - Department of Anesthesiology & Critical Care, Perelman School of Medicine, - University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: - Roderic.Eckenhoff@uphs.upenn.edu. -FAU - Laudansky, Krzysztof F -AU - Laudansky KF -LA - eng -GR - R01 AG031742/AG/NIA NIH HHS/United States -GR - NIH AG031742/AG/NIA NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120621 -PL - England -TA - Prog Neuropsychopharmacol Biol Psychiatry -JT - Progress in neuro-psychopharmacology & biological psychiatry -JID - 8211617 -SB - IM -MH - Alzheimer Disease/*etiology -MH - Anesthesia/*adverse effects -MH - Cognition Disorders/etiology -MH - Humans -MH - Postoperative Complications/*physiopathology -PMC - PMC3509241 -MID - NIHMS394929 -OTO - NOTNLM -OT - 3xTgAD -OT - ADNI -OT - ADRC -OT - ARDS -OT - Alzheimer Disease Neuro Imaging -OT - Alzheimer Disease Research Center -OT - Alzheimer transgenic mice -OT - Biomarkers -OT - CABG -OT - CSF -OT - Cytokines -OT - IL-10 -OT - IL-4 -OT - IL-6 -OT - Interleukin-10 -OT - Interleukin-4 -OT - Interleukin-6 -OT - LFA-1α -OT - MCI -OT - NSAID -OT - Neuroinflammation -OT - POCD -OT - Peripheral inflammation -OT - SAE -OT - TGFβ -OT - TNFα -OT - Tumor Necrosis Factor-α -OT - WT -OT - adult respiratory distress syndrome -OT - cerebrospinal fluid -OT - coronary artery bypass surgery -OT - leukocyte functional antigen-1α -OT - mild cognitive impairment -OT - non-steroidal anti-inflammatory drugs -OT - post-operative cognitive decline -OT - sepsis associated encephalopathy -OT - transforming growth factor-β -OT - triple transgenic mouse model of Alzheimer disease -OT - wild type -EDAT- 2012/06/26 06:00 -MHDA- 2014/07/06 06:00 -PMCR- 2014/12/02 -CRDT- 2012/06/26 06:00 -PHST- 2012/03/20 00:00 [received] -PHST- 2012/06/12 00:00 [revised] -PHST- 2012/06/17 00:00 [accepted] -PHST- 2012/06/26 06:00 [entrez] -PHST- 2012/06/26 06:00 [pubmed] -PHST- 2014/07/06 06:00 [medline] -PHST- 2014/12/02 00:00 [pmc-release] -AID - S0278-5846(12)00146-7 [pii] -AID - 10.1016/j.pnpbp.2012.06.011 [doi] -PST - ppublish -SO - Prog Neuropsychopharmacol Biol Psychiatry. 2013 Dec 2;47:162-6. doi: - 10.1016/j.pnpbp.2012.06.011. Epub 2012 Jun 21. - -PMID- 18598700 -OWN - NLM -STAT- MEDLINE -DCOM- 20090122 -LR - 20250529 -IS - 1095-8584 (Electronic) -IS - 0022-2828 (Linking) -VI - 45 -IP - 4 -DP - 2008 Oct -TI - Cardiac stem cells and myocardial disease. -PG - 505-13 -LID - 10.1016/j.yjmcc.2008.05.025 [doi] -AB - Recent data indicate that the heart is a self-renewing organ and contains a pool - of progenitor cells (PCs). According to the new paradigm, this resident - population of multipotent undifferentiated cells gives rise to myocytes, - endothelial cells, smooth muscle cells and fibroblasts. Understanding the - function of cardiac PCs is critical for the implementation of these cells in the - treatment of the diseased human heart. However, cardiac repair is an extremely - complex phenomenon. Efficient myocardial regeneration requires restoration of - segmental and focal areas of myocardial scarring, replacement of damaged coronary - arteries, arterioles and capillaries, and substitution of hypertrophied poorly - contracting myocytes with smaller better functioning parenchymal cells. To - achieve these goals, the acquisition of a more profound knowledge of the biology - of cardiac PCs cells and their fate following pathologic insults represents an - essential need. -FAU - Kajstura, Jan -AU - Kajstura J -AD - Department of Anesthesia, and Division of Cardiology, Brigham and Women's - Hospital, Harvard Medical School, Boston, MA 02115, USA. - jkajstura@zeus.bwh.harvard.edu -FAU - Urbanek, Konrad -AU - Urbanek K -FAU - Rota, Marcello -AU - Rota M -FAU - Bearzi, Claudia -AU - Bearzi C -FAU - Hosoda, Toru -AU - Hosoda T -FAU - Bolli, Roberto -AU - Bolli R -FAU - Anversa, Piero -AU - Anversa P -FAU - Leri, Annarosa -AU - Leri A -LA - eng -GR - R21 HL094894/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20080613 -PL - England -TA - J Mol Cell Cardiol -JT - Journal of molecular and cellular cardiology -JID - 0262322 -SB - IM -MH - Animals -MH - Heart Diseases/*metabolism/pathology/*therapy -MH - Humans -MH - Multipotent Stem Cells/*metabolism/pathology -MH - Myocardium/*metabolism/pathology -MH - *Stem Cell Transplantation -RF - 83 -EDAT- 2008/07/05 09:00 -MHDA- 2009/01/23 09:00 -CRDT- 2008/07/05 09:00 -PHST- 2008/01/01 00:00 [received] -PHST- 2008/05/03 00:00 [revised] -PHST- 2008/05/25 00:00 [accepted] -PHST- 2008/07/05 09:00 [pubmed] -PHST- 2009/01/23 09:00 [medline] -PHST- 2008/07/05 09:00 [entrez] -AID - S0022-2828(08)00473-2 [pii] -AID - 10.1016/j.yjmcc.2008.05.025 [doi] -PST - ppublish -SO - J Mol Cell Cardiol. 2008 Oct;45(4):505-13. doi: 10.1016/j.yjmcc.2008.05.025. Epub - 2008 Jun 13. - -PMID- 18379229 -OWN - NLM -STAT- MEDLINE -DCOM- 20080428 -LR - 20120910 -IS - 1530-0293 (Electronic) -IS - 0090-3493 (Linking) -VI - 36 -IP - 4 -DP - 2008 Apr -TI - Transfusion of packed red blood cells in patients with ischemic heart disease. -PG - 1068-74 -LID - 10.1097/CCM.0b013e318169251f [doi] -AB - OBJECTIVE: To review the current literature concerning the utility of and - complications associated with transfusion of packed red blood cells (PRBC) in - medical and surgical patients with ischemic heart disease. DATA SOURCES, STUDY - SELECTION, AND DATA EXTRACTION: The PubMed database of the National Library of - Medicine was searched for all studies investigating the use of PRBC in medical - and surgical patients with cardiac disease published since 1999. Relevant - background literature from before that date was reviewed for inclusion as well. - DATA SYNTHESIS: An extensive body of literature has accumulated evaluating the - safety and efficacy of transfusion as a therapeutic modality in a wide variety of - critically ill patients, including patients with cardiac disease. Most, but not - all, of these studies have been retrospective in nature, and methodologies have - varied from study to study. Some have involved retrospective reviews of patient - records, some have been retrospective analyses of detailed databases - prospectively collected for other purposes, and some have been prospective - randomized or observational studies. Despite the variability in data sources and - study design, with a handful of exceptions, the preponderance of data indicates - that transfusion of PRBC in the population of patients with ischemic heart - disease is of limited clinical utility and may carry the potential for serious - adverse consequences. CONCLUSIONS: Based on the current literature, there appears - to be no indication for routine transfusion in patients with non-ST-elevation - acute coronary syndrome, although anemic patients with ST-elevation myocardial - infarction may benefit from this intervention. However, the specific indications - for transfusion in this population remain ill-defined. -FAU - Gerber, David R -AU - Gerber DR -AD - University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical - School at Camden, and Medical-Surgical Intensive Care Unit, Cooper University - Hospital, Camden, NJ, USA. gerber-dave@cooperhealth.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Med -JT - Critical care medicine -JID - 0355501 -SB - IM -CIN - Crit Care Med. 2008 Nov;36(11):3126-7; author reply 3127. doi: - 10.1097/CCM.0b013e31818be422. PMID: 18941333 -MH - *Anemia/complications/therapy -MH - Clinical Trials as Topic -MH - Erythrocyte Transfusion/*adverse effects -MH - Humans -MH - *Myocardial Ischemia/complications/mortality/therapy -MH - Postoperative Complications -MH - Risk Factors -MH - Treatment Failure -RF - 47 -EDAT- 2008/04/02 09:00 -MHDA- 2008/04/29 09:00 -CRDT- 2008/04/02 09:00 -PHST- 2008/04/02 09:00 [pubmed] -PHST- 2008/04/29 09:00 [medline] -PHST- 2008/04/02 09:00 [entrez] -AID - 00003246-200804000-00005 [pii] -AID - 10.1097/CCM.0b013e318169251f [doi] -PST - ppublish -SO - Crit Care Med. 2008 Apr;36(4):1068-74. doi: 10.1097/CCM.0b013e318169251f. - -PMID- 16370332 -OWN - NLM -STAT- MEDLINE -DCOM- 20060112 -LR - 20070515 -IS - 0171-2004 (Print) -IS - 0171-2004 (Linking) -IP - 174 -DP - 2006 -TI - Neovascularization and cardiac repair by bone marrow-derived stem cells. -PG - 283-98 -AB - Postinfarction congestive heart failure with impaired systolic left ventricular - function is a loss of cardiomyocyte disease. Adult stem or progenitor cells from - the bone marrow and the peripheral blood have been experimentally shown to - differentiate towards endothelial cells and cardiomyocytes under the appropriate - conditions. The use of autologous adult stem cells for neovascularization and - cardiac regeneration is a promising concept and has shown benefit in pilot - clinical trails enrolling postinfarction patients with coronary artery disease. - Cell therapy may act through differentiation into and thus replacement of - cardiomyocytes and/or neovascularization, the formation of new vessels in the - adult organism. Moreover, the release of factors acting in a paracrine manner may - contribute to neovascularization and scar remodelling. In this review, the - experimental data regarding neovascularization and cardiomyocyte formation from - adult stem/progenitor cells are discussed. -FAU - Badorff, C -AU - Badorff C -AD - Department of Molecular Cardiology, University of Frankfurt, Theodor Stern-Kai 7, - 60590 Frankfurt, Germany. -FAU - Dimmeler, S -AU - Dimmeler S -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Handb Exp Pharmacol -JT - Handbook of experimental pharmacology -JID - 7902231 -SB - IM -MH - Animals -MH - Bone Marrow Cells/*cytology -MH - Cell Differentiation -MH - Humans -MH - Myocytes, Cardiac/*cytology/*pathology/physiology -MH - Neovascularization, Physiologic/*physiology -MH - Stem Cells/*cytology/*physiology -MH - Wound Healing/*physiology -RF - 70 -EDAT- 2005/12/24 09:00 -MHDA- 2006/01/13 09:00 -CRDT- 2005/12/24 09:00 -PHST- 2005/12/24 09:00 [pubmed] -PHST- 2006/01/13 09:00 [medline] -PHST- 2005/12/24 09:00 [entrez] -PST - ppublish -SO - Handb Exp Pharmacol. 2006;(174):283-98. - -PMID- 20513448 -OWN - NLM -STAT- MEDLINE -DCOM- 20100930 -LR - 20161125 -IS - 1558-4623 (Electronic) -IS - 0001-2998 (Linking) -VI - 40 -IP - 4 -DP - 2010 Jul -TI - Altered biodistribution and incidental findings on myocardial perfusion imaging. -PG - 257-70 -LID - 10.1053/j.semnuclmed.2010.03.005 [doi] -AB - Myocardial perfusion studies routinely are performed to evaluate for the presence - and extent of coronary artery disease. The findings have prognostic and - therapeutic implications. Routine display of the raw projection images allows - visualization of regions adjacent to the heart in which there may be incidental - findings that are nonsignificant but in other instances are clinically important. - Such incidental findings may cause artifacts and therefore need to be considered - when interpreting the perfusion images. These findings may also indicate other - cardiovascular conditions and sometimes show important noncardiac pathology. To - properly interpret these findings, one must be familiar with normal uptake and - kinetics of the cardiac perfusion tracers and have a solid understanding of image - acquisition, reconstruction, and processing techniques. Thus, on single-photon - emission computed tomography radionuclide myocardial perfusion imaging, raw - projection images must be reviewed routinely and systematically for any - incidental findings that might affect image interpretation and/or could indicate - other disease. -CI - Copyright 2010 Elsevier Inc. All rights reserved. -FAU - Chamarthy, Murthy -AU - Chamarthy M -AD - Department of Nuclear Medicine, Montefiore Medical Center, Albert Einstein - College of Medicine, Bronx, NY 10467-2490, USA. -FAU - Travin, Mark I -AU - Travin MI -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Semin Nucl Med -JT - Seminars in nuclear medicine -JID - 1264464 -RN - 0 (Radiopharmaceuticals) -SB - IM -MH - *Artifacts -MH - Cardiovascular Diseases/*diagnostic imaging/*metabolism -MH - Humans -MH - Incidental Findings -MH - Myocardial Perfusion Imaging/*methods -MH - Radiopharmaceuticals/*pharmacokinetics -MH - Tissue Distribution -MH - Tomography, Emission-Computed/*methods -RF - 85 -EDAT- 2010/06/02 06:00 -MHDA- 2010/10/01 06:00 -CRDT- 2010/06/02 06:00 -PHST- 2010/06/02 06:00 [entrez] -PHST- 2010/06/02 06:00 [pubmed] -PHST- 2010/10/01 06:00 [medline] -AID - S0001-2998(10)00020-6 [pii] -AID - 10.1053/j.semnuclmed.2010.03.005 [doi] -PST - ppublish -SO - Semin Nucl Med. 2010 Jul;40(4):257-70. doi: 10.1053/j.semnuclmed.2010.03.005. - -PMID- 21395517 -OWN - NLM -STAT- MEDLINE -DCOM- 20110614 -LR - 20191112 -IS - 1050-6934 (Print) -IS - 1050-6934 (Linking) -VI - 20 -IP - 3 -DP - 2010 -TI - Evaluation of the efficacy and performance of medical implants: a review. -PG - 173-85 -AB - An implant can be defined, in a medical context, as biological or artificial - materials inserted or grafted into the body. Implants may be sensory devices - (cochlear, ocular), mechanical devices that are 'passive' (orthopedic joint - replacements and fixation plates, dental implants, coronary artery stents and - vascular grafts) or 'active' (left ventricular assist devices, heart valves) - electrophysiological stimulation devices (cardiac or gastric pacemakers, - implantable cardiac defibrillators, functional electrical stimulators for - epilepsy or Parkinson's disease) or medication administration devices (insulin or - analgesic delivery pumps) or intra-ocular sustained drug release implants. - Implantation has had a long history in several subspecialties of medicine. - Evaluation of the efficacy of implants is a multifactorial issue. Several - variables need to be considered while studying the rejection of the implants such - as pathophysiological mechanisms, malfunction, design shortcomings and improper - implementation/implantation by a medical team. This paper identifies a variety of - modes of failure and how they affect the overall efficacy of the device - technologies. Suggestions for improvement, as outlined in the literature, will be - examined. -FAU - Lodder, Anton -AU - Lodder A -AD - Department of Medicine, McMaster Univesity, Hamilton, Ontario, Canada. -FAU - Kamath, Markad V -AU - Kamath MV -FAU - Upton, Adrian R -AU - Upton AR -FAU - Armstrong, David -AU - Armstrong D -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Long Term Eff Med Implants -JT - Journal of long-term effects of medical implants -JID - 9110830 -MH - Humans -MH - Infusion Pumps, Implantable -MH - *Prostheses and Implants -MH - Prosthesis Failure/*etiology -EDAT- 2010/01/01 00:00 -MHDA- 2011/06/15 06:00 -CRDT- 2011/03/15 06:00 -PHST- 2011/03/15 06:00 [entrez] -PHST- 2010/01/01 00:00 [pubmed] -PHST- 2011/06/15 06:00 [medline] -AID - 12afd56d284de467,0986824c7512f6ec [pii] -AID - 10.1615/jlongtermeffmedimplants.v20.i3.20 [doi] -PST - ppublish -SO - J Long Term Eff Med Implants. 2010;20(3):173-85. doi: - 10.1615/jlongtermeffmedimplants.v20.i3.20. - -PMID- 19089340 -OWN - NLM -STAT- MEDLINE -DCOM- 20090309 -LR - 20131121 -IS - 0171-2004 (Print) -IS - 0171-2004 (Linking) -IP - 191 -DP - 2009 -TI - cGMP in the vasculature. -PG - 447-67 -LID - 10.1007/978-3-540-68964-5_19 [doi] -AB - Cyclic guanosine 3', 5'-monophosphate (cGMP) plays an integral role in the - control of vascular function. Generated from guanylate cyclases in response to - the endogenous ligands, nitric oxide (NO) and natriuretic peptides (NPs), cGMP - influences a number of vascular cell types and regulates vasomotor tone, - endothelial permeability, cell growth and differentiation, as well as platelet - and blood cell interactions. Reciprocal regulation of the NO-cGMP and NP-cGMP - pathways is evident in the vasculature such that one cGMP generating system may - compensate for the dysfunction of the other. Indeed, aberrant cGMP production - and/or signalling accompanies many vascular disorders such as hypertension, - atherosclerosis, coronary artery disease and diabetic complications. This chapter - highlights the main vascular functions of cGMP, its role in disease and the - resulting current and potential therapeutic applications. With respect to - pulmonary hypertension, heart failure and erectile dysfunction, as well as cGMP - signal transduction, the reader is specifically referred to other dedicated - chapters. -FAU - Kemp-Harper, Barbara -AU - Kemp-Harper B -AD - Department of Pharmacology, Monash University, Melbourne (Clayton), VIC, 3800, - Australia. barbara.kemp@med.monash.edu.au -FAU - Schmidt, Harald H H W -AU - Schmidt HH -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Handb Exp Pharmacol -JT - Handbook of experimental pharmacology -JID - 7902231 -RN - H2D2X058MU (Cyclic GMP) -SB - IM -MH - Animals -MH - Capillary Permeability/physiology -MH - Cyclic GMP/*metabolism -MH - Endothelium, Vascular/physiology -MH - Humans -MH - Signal Transduction/*physiology -MH - Vascular Diseases/*physiopathology -RF - 150 -EDAT- 2008/12/18 09:00 -MHDA- 2009/03/10 09:00 -CRDT- 2008/12/18 09:00 -PHST- 2008/12/18 09:00 [entrez] -PHST- 2008/12/18 09:00 [pubmed] -PHST- 2009/03/10 09:00 [medline] -AID - 10.1007/978-3-540-68964-5_19 [doi] -PST - ppublish -SO - Handb Exp Pharmacol. 2009;(191):447-67. doi: 10.1007/978-3-540-68964-5_19. - -PMID- 23016723 -OWN - NLM -STAT- MEDLINE -DCOM- 20130816 -LR - 20180605 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 19 -IP - 9 -DP - 2013 -TI - Refractory angina pectoris: lessons from the past and current perspectives. -PG - 1658-72 -AB - Refractory angina pectoris constitutes a manifestation of severe ischemic heart - disease that cannot be treated adequately either with conventional medication or - with interventional techniques including percutaneous coronary angioplasty - (PTCA). As a result, new therapeutic strategies, aiming on angiogenesis, were - evolved in order to improve functional class and health related quality of life - (HRQOL) indices. Among them, gene therapy constitutes a very promising - alternative treatment for these patients. In this review, we will describe i) the - definition of refractory angina ii) pathophysiology of angiogenesis, iii) routine - as well as novel imaging techniques of neovascularization and iv) current - treatment options for refractory angina. Secondly we will review the main - angiogenic clinical trials, which will also be commented regarding their - effectiveness to reduce the recurrency of angina symptoms and improve - health-related quality-of-life, as well as the functional class of patients with - chronic ischemic disease. -FAU - Vavuranakis, Manolis -AU - Vavuranakis M -AD - 1st Dept. of Cardiology, Hippokration Hospital, Medical School, National & - Kapodistrian University of Athens, 114 V.Sofia Ave, 115 28, Greece. - vavouran@otenet.gr -FAU - Kariori, Maria -AU - Kariori M -FAU - Kalogeras, Konstantinos -AU - Kalogeras K -FAU - Vrachatis, Dimitrios -AU - Vrachatis D -FAU - Moldovan, Carmen -AU - Moldovan C -FAU - Tousoulis, Dimitris -AU - Tousoulis D -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Angina Pectoris/physiopathology/*therapy -MH - Cardiovascular Agents/therapeutic use -MH - Genetic Therapy -MH - Humans -MH - Magnetic Resonance Imaging -MH - Neovascularization, Pathologic -MH - Positron-Emission Tomography -EDAT- 2012/09/29 06:00 -MHDA- 2013/08/21 06:00 -CRDT- 2012/09/29 06:00 -PHST- 2012/08/31 00:00 [received] -PHST- 2012/09/17 00:00 [accepted] -PHST- 2012/09/29 06:00 [entrez] -PHST- 2012/09/29 06:00 [pubmed] -PHST- 2013/08/21 06:00 [medline] -AID - CPD-EPUB-20120918-11 [pii] -PST - ppublish -SO - Curr Pharm Des. 2013;19(9):1658-72. - -PMID- 20048526 -OWN - NLM -STAT- MEDLINE -DCOM- 20100226 -LR - 20220409 -IS - 0091-3847 (Print) -IS - 0091-3847 (Linking) -VI - 37 -IP - 3 -DP - 2009 Oct -TI - Impact of psychosocial risk factors on the heart: changing paradigms and - perceptions. -PG - 35-7 -LID - 10.3810/psm.2009.10.1727 [doi] -AB - To combat cardiovascular disease (CVD), physicians and allied health care - professionals often focus on modifying conventional risk factors such as - cigarette smoking, hypertension, hypercholesterolemia, and diabetes. However, a - recent review of published research demonstrated that 75% to 90% of coronary - artery disease (CAD) incidence is explained by these risk factors, either alone - or in combination. This has stimulated a vigorous search for other correctable - risk factors (ie, to explain the remaining incidence [10%-25%]), including - genetic anomalies, markers of inflammation (C-reactive protein, - lipoprotein-associated phospholipase A2), and specific lipid/lipoprotein - particles to enhance risk stratification. Nevertheless, an escalating body of - research provides strong evidence for the adverse effects of psychosocial factors - in the development of CVD and in the prognosis of patients with CAD. -FAU - Franklin, Barry A -AU - Franklin BA -AD - William Beaumont Hospital, Royal Oak, MI 48073, USA. bfranklin@beaumont.edu -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Phys Sportsmed -JT - The Physician and sportsmedicine -JID - 0427461 -SB - IM -MH - Cardiovascular Diseases/epidemiology/*prevention & control/*psychology -MH - Comorbidity -MH - Depression/psychology -MH - Humans -MH - Incidence -MH - Mood Disorders/psychology -MH - Personality -MH - Risk Factors -MH - Social Isolation/psychology -MH - Stress, Psychological/psychology -RF - 21 -EDAT- 2010/01/06 06:00 -MHDA- 2010/02/27 06:00 -CRDT- 2010/01/06 06:00 -PHST- 2010/01/06 06:00 [entrez] -PHST- 2010/01/06 06:00 [pubmed] -PHST- 2010/02/27 06:00 [medline] -AID - 10.3810/psm.2009.10.1727 [doi] -PST - ppublish -SO - Phys Sportsmed. 2009 Oct;37(3):35-7. doi: 10.3810/psm.2009.10.1727. - -PMID- 17030942 -OWN - NLM -STAT- MEDLINE -DCOM- 20061016 -LR - 20240322 -IS - 1488-2329 (Electronic) -IS - 0820-3946 (Print) -IS - 0820-3946 (Linking) -VI - 175 -IP - 8 -DP - 2006 Oct 10 -TI - Clinical applications of cardiovascular magnetic resonance imaging. -PG - 911-7 -AB - Cardiovascular magnetic resonance imaging (MRI) has evolved from an effective - research tool into a clinically proven, safe and comprehensive imaging modality. - It provides anatomic and functional information in acquired and congenital heart - disease and is the most precise technique for quantification of ventricular - volumes, function and mass. Owing to its excellent interstudy reproducibility, - cardiovascular MRI is the optimal method for assessment of changes in ventricular - parameters after therapeutic intervention. Delayed contrast enhancement is an - accurate and robust method used in the diagnosis of ischemic and nonischemic - cardiomyopathies and less common diseases, such as cardiac sarcoidosis and - myocarditis. First-pass magnetic contrast myocardial perfusion is becoming an - alternative to radionuclide techniques for the detection of coronary - atherosclerotic disease. In this review we outline the techniques used in - cardiovascular MRI and discuss the most common clinical applications. -FAU - Marcu, Constantin B -AU - Marcu CB -AD - Cardiac Diagnostic Unit, Hospital of Saint Raphael, New Haven, Conn 06511, USA. - bogmarcu@pol.net -FAU - Beek, Aernout M -AU - Beek AM -FAU - van Rossum, Albert C -AU - van Rossum AC -LA - eng -PT - Journal Article -PT - Review -PL - Canada -TA - CMAJ -JT - CMAJ : Canadian Medical Association journal = journal de l'Association medicale - canadienne -JID - 9711805 -SB - IM -MH - Cardiovascular Diseases/*diagnosis -MH - Cardiovascular System/*pathology -MH - Hand Deformities, Congenital/diagnosis -MH - Humans -MH - Magnetic Resonance Imaging/*methods -PMC - PMC1586078 -EDAT- 2006/10/13 09:00 -MHDA- 2006/10/17 09:00 -PMCR- 2006/10/10 -CRDT- 2006/10/13 09:00 -PHST- 2006/10/13 09:00 [pubmed] -PHST- 2006/10/17 09:00 [medline] -PHST- 2006/10/13 09:00 [entrez] -PHST- 2006/10/10 00:00 [pmc-release] -AID - 175/8/911 [pii] -AID - 0002792-200610100-00023 [pii] -AID - 10.1503/cmaj.060566 [doi] -PST - ppublish -SO - CMAJ. 2006 Oct 10;175(8):911-7. doi: 10.1503/cmaj.060566. - -PMID- 18811747 -OWN - NLM -STAT- MEDLINE -DCOM- 20081230 -LR - 20220321 -IS - 1747-4949 (Electronic) -IS - 1747-4930 (Linking) -VI - 3 -IP - 4 -DP - 2008 Nov -TI - The burden of stroke in Pakistan. -PG - 293-6 -LID - 10.1111/j.1747-4949.2008.00214.x [doi] -AB - Epidemiologic literature on stroke burden, patterns of stroke is almost non - existent from Pakistan. However, several hospital-based case series on the - subject are available, mainly published in local medical journals. Despite the - fact that true stroke incidence and prevalence of stroke in Pakistan is not - known, the burden is assumed to be high because of highly prevalent stroke risk - factors (hypertension, diabetes mellitus, coronary artery disease, dyslipidemia - and smoking) in the community. High burden of these conventional stroke risk - factors is further compounded by lack of awareness, poor compliance hence poor - control, and inappropriate management/treatment practices. In addition certain - risk factors like rheumatic valvular heart disease may be more prevalent in - Pakistan. We reviewed the existing literature on stroke risk factors in - community, the risk factor prevalence among stroke patients, patterns of stroke, - out come of stroke, availability of diagnostic services/facilities related to - stroke and resources for stroke care in Pakistan. -FAU - Khealani, Bhojo A -AU - Khealani BA -AD - Neurology Section, Department of Medicine, Aga Khan University Hospital, Karachi, - Pakistan. -FAU - Wasay, Mohammad -AU - Wasay M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Int J Stroke -JT - International journal of stroke : official journal of the International Stroke - Society -JID - 101274068 -SB - IM -MH - *Cost of Illness -MH - Developing Countries/*statistics & numerical data -MH - Humans -MH - Pakistan -MH - Risk Factors -MH - Stroke/diagnosis/*epidemiology/etiology -RF - 43 -EDAT- 2008/09/25 09:00 -MHDA- 2008/12/31 09:00 -CRDT- 2008/09/25 09:00 -PHST- 2008/09/25 09:00 [pubmed] -PHST- 2008/12/31 09:00 [medline] -PHST- 2008/09/25 09:00 [entrez] -AID - IJS214 [pii] -AID - 10.1111/j.1747-4949.2008.00214.x [doi] -PST - ppublish -SO - Int J Stroke. 2008 Nov;3(4):293-6. doi: 10.1111/j.1747-4949.2008.00214.x. - -PMID- 22461043 -OWN - NLM -STAT- MEDLINE -DCOM- 20130702 -LR - 20191112 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 19 -IP - 2 -DP - 2012 -TI - QRS fragmentation: diagnostic and prognostic significance. -PG - 114-21 -AB - Fragmentation of QRS (fQRS) complex is an easily evaluated non-invasive - electrocardiographic parameter. Fragmentation of narrow QRS is defined as - presence of an additional R wave (R') or notching in the nadir of the S wave, or - the presence of > 1 R' in 2 contiguous leads, corresponding to a major coronary - artery territory on the resting 12-lead ECG. Fragmentation of wide complex QRS - consists of various RSR patterns, with more than 2 R waves (R'') or more than 2 - notches in the R wave, or more than 2 notches in the downstroke or upstroke of - the S wave. Presence of fQRS has been associated with alternation of myocardial - activation due to myocardial scar and myocardial fibrosis. Initial studies - reported higher sensitivity of fQRS than Q wave for detecting myocardial scar and - postulated that the presence of fQRS could be a good predictor of cardiac events - among the patients with coronary artery disease. The presence of fQRS has been - investigated among the patients with ischemic and non-ischemic cardiomyopathy - suggesting that this ECG parameter may affect prognosis and risk of sudden - cardiac death, risk of implantable cardioverter-defibrillator therapy and - response to cardiac resynchronization therapy. In addition, there is evidence - that fQRS could play an important role as screening and prognostic tool among the - patients with Brugada syndrome, long QT syndrome, arrhythmogenic right - ventricular dysplasia and cardiac sarcoidosis. This paper reviews definition, - diagnostic and prognostic value of fQRS in different patient populations. -FAU - Pietrasik, Grzegorz -AU - Pietrasik G -AD - Division of Cardiovascular Medicine, Department of Medicine, University at - Buffalo, State University of New York, Buffalo, New York 14203, USA. - gmp11@buffalo.edu -FAU - Zaręba, Wojciech -AU - Zaręba W -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -SB - IM -MH - Arrhythmias, Cardiac/*diagnosis/pathology/physiopathology/therapy -MH - Cardiac Resynchronization Therapy -MH - Defibrillators, Implantable -MH - Electric Countershock/instrumentation -MH - *Electrocardiography -MH - Fibrosis -MH - Heart Conduction System/*physiopathology -MH - Humans -MH - Myocardial Ischemia/*diagnosis/pathology/physiopathology/therapy -MH - Myocardium/pathology -MH - Predictive Value of Tests -MH - Prognosis -EDAT- 2012/03/31 06:00 -MHDA- 2013/07/03 06:00 -CRDT- 2012/03/31 06:00 -PHST- 2012/03/31 06:00 [entrez] -PHST- 2012/03/31 06:00 [pubmed] -PHST- 2013/07/03 06:00 [medline] -AID - 10.5603/cj.2012.0022 [doi] -PST - ppublish -SO - Cardiol J. 2012;19(2):114-21. doi: 10.5603/cj.2012.0022. - -PMID- 18493844 -OWN - NLM -STAT- MEDLINE -DCOM- 20081218 -LR - 20211020 -IS - 1383-875X (Print) -IS - 1383-875X (Linking) -VI - 23 -IP - 1 -DP - 2008 Oct -TI - Modern noninvasive risk stratification in primary prevention of sudden cardiac - death. -PG - 23-8 -LID - 10.1007/s10840-008-9264-8 [doi] -AB - OBJECTIVE: Since the publication of MADIT II and SCD-HeFT, an implantable - cardioverter defibrillator (ICD) for primary prevention represents an - established, guideline-implemented therapeutic strategy. Facing such an enormous - amount of potential ICD recipients, the identification of an effective risk - stratification remains crucial. METHODS: This article reviews the tools of - noninvasive risk stratification which are currently used and defines an optimal - test configuration. This analysis focuses on the capacity of the tests regarding - to the negative predictive value to reduce unneeded devices. RESULTS: Presently, - no marker exists in terms of risk stratification which qualifies itself as gold - standard. However, encouraging results can be stated for microvolt T-wave - alternans (mTWA) providing a high negative predictive value. An increased QT - variability (QTv) and an impaired deceleration capacity are associated with an - excellent positive predictive value. Currently, only mTWA and QTv seem to be - suitable in ischemic and non-ischemic disease, but available data, especially in - non-ischemic patients, are too small to provide clear recommendations. - CONCLUSION: The most hopeful tools at hand in modern noninvasive risk evaluation - of sudden cardiac death in primary prevention seem to be mTWA and QTv. These - noninvasive methods provide the best negative predictive or positive predictive - value of all known parameters, while a higher rate of complete coronary - revascularizations in acute coronary syndromes might also reduce the number of - fatal arrhythmic events and therefore complicate the invention of an ideal risk - marker. -FAU - Kreuz, J -AU - Kreuz J -AD - Department of Medicine-Cardiology, University of Bonn, Sigmund-Freud-Str. 25, - 53105 Bonn, Germany. -FAU - Lickfett, L M -AU - Lickfett LM -FAU - Schwab, J O -AU - Schwab JO -LA - eng -PT - Journal Article -PT - Review -DEP - 20080521 -PL - Netherlands -TA - J Interv Card Electrophysiol -JT - Journal of interventional cardiac electrophysiology : an international journal of - arrhythmias and pacing -JID - 9708966 -SB - IM -MH - Arrhythmias, Cardiac/*classification/complications -MH - Death, Sudden, Cardiac/etiology/*prevention & control -MH - Defibrillators, Implantable/adverse effects -MH - Electrocardiography -MH - Heart Conduction System/*physiopathology -MH - Humans -MH - Predictive Value of Tests -MH - Primary Prevention -MH - Risk Assessment -MH - Ventricular Dysfunction, Left/complications -RF - 21 -EDAT- 2008/05/22 09:00 -MHDA- 2008/12/19 09:00 -CRDT- 2008/05/22 09:00 -PHST- 2008/01/25 00:00 [received] -PHST- 2008/04/09 00:00 [accepted] -PHST- 2008/05/22 09:00 [pubmed] -PHST- 2008/12/19 09:00 [medline] -PHST- 2008/05/22 09:00 [entrez] -AID - 10.1007/s10840-008-9264-8 [doi] -PST - ppublish -SO - J Interv Card Electrophysiol. 2008 Oct;23(1):23-8. doi: - 10.1007/s10840-008-9264-8. Epub 2008 May 21. - -PMID- 24689007 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20220331 -IS - 2305-7823 (Print) -IS - 2305-7823 (Electronic) -IS - 2305-7823 (Linking) -VI - 2013 -IP - 2 -DP - 2013 -TI - Peripheral arterial disease in the Middle East: Underestimated predictor of worse - outcome. -PG - 98-113 -LID - 10.5339/gcsp.2013.13 [doi] -AB - Peripheral arterial disease (PAD) is a common manifestation of systemic - atherosclerosis and is associated with significant morbidity and mortality. The - prevalence of PAD in the developed world is approximately 12% among adult - population, which is age-dependent and with men being affected slightly more than - women. Despite the strikingly high prevalence of PAD, the disease is - underdiagnosed. Surprisingly, more than 70% of primary health care providers in - the US were unaware of the presence of PAD in their patients. The clinical - presentation of PAD may vary from asymptomatic to intermittent claudication, - atypical leg pain, rest pain, ischemic ulcers, or gangrene. Claudication is the - typical symptomatic expression of PAD. However, the disease may remains - asymptomatic in up to 50% of all PAD patients. PAD has also been reported as a - marker of poor outcome among patients with coronary artery disease. Despite the - fact that the prevalence of atherosclerotic disease is increasing in the Middle - East with increasing cardiovascular risk factors (tobacco use, diabetes mellitus - and the metabolic syndrome), data regarding PAD incidence in the Middle East are - scarce. -FAU - El-Menyar, Ayman -AU - El-Menyar A -FAU - Al Suwaidi, Jassim -AU - Al Suwaidi J -AD - Department of cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar. -FAU - Al-Thani, Hassan -AU - Al-Thani H -AD - Vascular surgery, Hamad Medical Corporation, Doha, Qatar. -LA - eng -PT - Journal Article -PT - Review -DEP - 20131101 -PL - Qatar -TA - Glob Cardiol Sci Pract -JT - Global cardiology science & practice -JID - 101613130 -PMC - PMC3963749 -OTO - NOTNLM -OT - Middle East -OT - Peripheral arterial disease -EDAT- 2013/01/01 00:00 -MHDA- 2013/01/01 00:01 -PMCR- 2013/11/01 -CRDT- 2014/04/02 06:00 -PHST- 2012/01/12 00:00 [received] -PHST- 2013/04/11 00:00 [accepted] -PHST- 2014/04/02 06:00 [entrez] -PHST- 2013/01/01 00:00 [pubmed] -PHST- 2013/01/01 00:01 [medline] -PHST- 2013/11/01 00:00 [pmc-release] -AID - gcsp.2013.13 [pii] -AID - 10.5339/gcsp.2013.13 [doi] -PST - epublish -SO - Glob Cardiol Sci Pract. 2013 Nov 1;2013(2):98-113. doi: 10.5339/gcsp.2013.13. - eCollection 2013. - -PMID- 16960982 -OWN - NLM -STAT- MEDLINE -DCOM- 20061204 -LR - 20220317 -IS - 0163-7258 (Print) -IS - 0163-7258 (Linking) -VI - 111 -IP - 3 -DP - 2006 Sep -TI - 5-hydroxytryptamine receptors in the human cardiovascular system. -PG - 674-706 -AB - The human cardiovascular system is exposed to plasma 5-hydroxytryptamine (5-HT, - serotonin), usually released from platelets. 5-HT can produce harmful acute and - chronic effects. The acute cardiac effects of 5-HT consist of tachycardia - (preceded on occasion by a brief reflex bradycardia), increased atrial - contractility and production of atrial arrhythmias. Acute inotropic, lusitropic - and arrhythmic effects of 5-HT on human ventricle become conspicuous after - inhibition of phosphodiesterase (PDE) activity. Human cardiostimulation is - mediated through 5-HT4 receptors. Atrial and ventricular PDE3 activity exerts a - protective role against potentially harmful cardiostimulation. Chronic exposure - to high levels of 5-HT (from metastatic carcinoid tumours), the anorectic drug - fenfluramine and its metabolites, as well as the ecstasy drug - 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite - 3,4-methylenedioxyamphetamine (MDA) are associated with proliferative disease and - thickening of cardiac valves, mediated through 5-HT2B receptors. 5-HT2B receptors - have an obligatory physiological role in murine cardiac embryology but whether - this happens in humans requires research. Congenital heart block (CHB) is, on - occasion, associated with autoantibodies against 5-HT4 receptors. Acute vascular - constriction by 5-HT is usually shared by 5-HT1B and 5-HT2A receptors, except in - intracranial arteries which constrict only through 5-HT1B receptors. Both 5-HT1B - and 5-HT2A receptors can mediate coronary artery spasm but only 5-HT1B receptors - appear involved in coronary spasm of patients treated with triptans or with - Prinzmetal angina. 5-HT2A receptors constrict the portal venous system including - oesophageal collaterals in cirrhosis. Chronic exposure to 5-HT can contribute to - pulmonary hypertension through activation of constrictor 5-HT1B receptors and - proliferative 5-HT2B receptors, and possibly through direct intracellular - effects. -FAU - Kaumann, Alberto J -AU - Kaumann AJ -AD - Department of Physiology, University of Cambridge, UK. -FAU - Levy, Finn Olav -AU - Levy FO -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Pharmacol Ther -JT - Pharmacology & therapeutics -JID - 7905840 -RN - 0 (Receptors, Serotonin) -RN - 333DO1RDJY (Serotonin) -SB - IM -MH - Animals -MH - Blood Vessels/*physiology -MH - Cardiovascular Diseases/*etiology -MH - *Heart Rate -MH - Humans -MH - Mutation -MH - *Myocardial Contraction -MH - Polymorphism, Genetic -MH - Receptors, Serotonin/genetics/*physiology -MH - Serotonin/physiology -RF - 385 -EDAT- 2006/09/09 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/09/09 09:00 -PHST- 2006/09/09 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/09/09 09:00 [entrez] -AID - 10.1016/j.pharmthera.2005.12.004 [doi] -PST - ppublish -SO - Pharmacol Ther. 2006 Sep;111(3):674-706. doi: 10.1016/j.pharmthera.2005.12.004. - -PMID- 20736112 -OWN - NLM -STAT- MEDLINE -DCOM- 20100914 -LR - 20100825 -IS - 1557-9859 (Electronic) -IS - 0025-7125 (Linking) -VI - 94 -IP - 5 -DP - 2010 Sep -TI - Snoring and obstructive sleep apnea. -PG - 1047-55 -LID - 10.1016/j.mcna.2010.05.002 [doi] -AB - Obstructive sleep apnea (OSA) may be associated with myriad clinical consequences - such as increased risk of systemic hypertension, coronary vascular disease, - congestive heart failure, cerebrovascular disease, glucose intolerance, - impotence, obesity, pulmonary hypertension, gastroesophageal reflux, and impaired - concentration. Nonetheless, OSA remains undiagnosed in 82% of men and 93% of - women with the condition. Early identification and treatment of OSA provides - significant relief for individuals, prevents complications of OSA, and reduces - overall health care costs. Better understanding of the pathogenesis, risk - factors, diagnosis, and treatment of OSA has the potential to improve early - recognition of OSA and prevention of adverse effects on the individual and - society. -CI - Copyright 2010 Elsevier Inc. All rights reserved. -FAU - Ulualp, Seckin O -AU - Ulualp SO -AD - Department of Otolaryngology-Head and Neck Surgery, University of Texas - Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9035, - USA. seckin.ulualp@utsouthwestern.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Med Clin North Am -JT - The Medical clinics of North America -JID - 2985236R -SB - IM -MH - Adult -MH - Child -MH - Continuous Positive Airway Pressure -MH - Humans -MH - Physical Examination -MH - *Severity of Illness Index -MH - Sleep Apnea, Obstructive/*diagnosis/*physiopathology/therapy -MH - Snoring/*physiopathology -RF - 59 -EDAT- 2010/08/26 06:00 -MHDA- 2010/09/16 06:00 -CRDT- 2010/08/26 06:00 -PHST- 2010/08/26 06:00 [entrez] -PHST- 2010/08/26 06:00 [pubmed] -PHST- 2010/09/16 06:00 [medline] -AID - S0025-7125(10)00076-3 [pii] -AID - 10.1016/j.mcna.2010.05.002 [doi] -PST - ppublish -SO - Med Clin North Am. 2010 Sep;94(5):1047-55. doi: 10.1016/j.mcna.2010.05.002. - -PMID- 21191425 -OWN - NLM -STAT- MEDLINE -DCOM- 20111014 -LR - 20240915 -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Print) -IS - 1176-6344 (Linking) -VI - 6 -DP - 2010 Nov 23 -TI - Cardio classics revisited--focus on the role of candesartan. -PG - 1047-63 -LID - 10.2147/VHRM.S9433 [doi] -AB - Angiotensin II receptor blockers (ARBs) are antihypertensive agents with - considerable evidence of efficacy and safety for the reduction of cardiovascular - (CV) disease risk in numerous patient populations across the CV continuum. There - are several agents within this class, all of which have contributed to various - degrees, to this evidence base. The evidence with ARBs continues to accumulate, - with ongoing trials investigating their role in additional patient populations, - potentially expanding their efficacy across a broad spectrum of CV disease - states. Cardiovascular disease (CVD) is a leading cause of death around the - world, accounting for approximately 29.2% of total global deaths. Of all the - deaths attributed to CVD, approximately 43% are due to ischemic heart disease, - 33% to cerebrovascular disease, and 23% to hypertensive and other heart - conditions. CVD has been represented as a "CV continuum". This continuum concept - can be used to describe CVD in general or in specific vascular beds (eg, coronary - artery disease or cerebrovascular disease). This review article will discuss the - results of the landmark ARB candesartan clinical trials published over the past - decade. The evidence presented spans the entire CV continuum, including the - effects of ARBs in at-risk patients, stroke, myocardial infarction (MI), and - heart failure (HF), as well as a brief discussion of ongoing trials. -FAU - De Rosa, Maria Leonarda -AU - De Rosa ML -AD - University of Naples Federico II, Department of Cardiology, Naples, Italy. - marialeonarda.derosa@unina.it -LA - eng -PT - Journal Article -PT - Review -DEP - 20101123 -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -RN - 0 (Angiotensin Receptor Antagonists) -RN - 0 (Antihypertensive Agents) -RN - 0 (Benzimidazoles) -RN - 0 (Biphenyl Compounds) -RN - 0 (Tetrazoles) -RN - S8Q36MD2XX (candesartan) -SB - IM -MH - Angiotensin Receptor Antagonists/pharmacology/*therapeutic use -MH - Antihypertensive Agents/pharmacology/standards/*therapeutic use -MH - Benzimidazoles/pharmacology/standards/*therapeutic use -MH - Biphenyl Compounds -MH - Cardiovascular Diseases/*drug therapy/*prevention & control -MH - Clinical Trials as Topic -MH - Diabetes Mellitus, Type 2/prevention & control -MH - Humans -MH - Hypertension/drug therapy/prevention & control -MH - Randomized Controlled Trials as Topic -MH - Tetrazoles/pharmacology/standards/*therapeutic use -MH - Treatment Outcome -PMC - PMC3004508 -OTO - NOTNLM -OT - angiotensin II receptor blockers -OT - candesartan -OT - cardiovascular disease -EDAT- 2010/12/31 06:00 -MHDA- 2011/10/15 06:00 -PMCR- 2010/11/23 -CRDT- 2010/12/31 06:00 -PHST- 2010/11/23 00:00 [received] -PHST- 2010/12/31 06:00 [entrez] -PHST- 2010/12/31 06:00 [pubmed] -PHST- 2011/10/15 06:00 [medline] -PHST- 2010/11/23 00:00 [pmc-release] -AID - vhrm-6-1047 [pii] -AID - 10.2147/VHRM.S9433 [doi] -PST - epublish -SO - Vasc Health Risk Manag. 2010 Nov 23;6:1047-63. doi: 10.2147/VHRM.S9433. - -PMID- 22824253 -OWN - NLM -STAT- MEDLINE -DCOM- 20130729 -LR - 20131122 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 163 -IP - 2 -DP - 2013 Feb 20 -TI - Angina pectoris in women: focus on microvascular disease. -PG - 132-40 -LID - S0167-5273(12)00938-2 [pii] -LID - 10.1016/j.ijcard.2012.07.001 [doi] -AB - Ischemic heart disease (IHD) is the leading cause of death among women in Western - countries, and it is associated with higher morbidity and mortality than in men. - Nevertheless, IHD in women remains underdiagnosed and undertreated, and the - misperception that females are "protected" against cardiovascular disease leads - to underestimation of their cardiovascular risk; instead, women with chest pain - have a high risk of cardiovascular events. Women suffering from angina pectoris - tend to have different characteristics compared to men, with a high prevalence of - non-significant coronary artery disease. Angina in women is more commonly - microvascular in origin than in men, and therefore standard diagnostic algorithms - may be suboptimal for women. This different pathophysiology impacts clinical - management of IHD in women. While response to medical therapy may differ in - women, they are scarcely represented in clinical trials. Therefore, solid data in - terms of gender efficacy of antianginal drugs are lacking, and particularly when - angina is microvascular in origin women often continue to be symptomatic despite - maximal therapy with classical antianginal drugs. Recently, new molecules have - shown promising results in women. In conclusion, women with angina are a group of - patients in whom it seems appropriate to concentrate efforts aimed at reducing - morbidity and improving quality of life. -CI - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved. -FAU - Zuchi, Cinzia -AU - Zuchi C -AD - Department of Cardiology, University of Perugia School of Medicine, Perugia, - Italy. -FAU - Tritto, Isabella -AU - Tritto I -FAU - Ambrosio, Giuseppe -AU - Ambrosio G -LA - eng -PT - Journal Article -PT - Review -DEP - 20120721 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -SB - IM -CIN - Int J Cardiol. 2013 Oct 3;168(3):3012-3. doi: 10.1016/j.ijcard.2013.04.055. PMID: - 23664441 -MH - Angina Pectoris/diagnosis/physiopathology/therapy -MH - Female -MH - Humans -MH - Male -MH - *Microvascular Angina/diagnosis/physiopathology/therapy -MH - Myocardial Ischemia/diagnosis/physiopathology/therapy -MH - Prognosis -MH - Sex Factors -EDAT- 2012/07/25 06:00 -MHDA- 2013/07/31 06:00 -CRDT- 2012/07/25 06:00 -PHST- 2011/08/24 00:00 [received] -PHST- 2012/07/07 00:00 [revised] -PHST- 2012/07/07 00:00 [accepted] -PHST- 2012/07/25 06:00 [entrez] -PHST- 2012/07/25 06:00 [pubmed] -PHST- 2013/07/31 06:00 [medline] -AID - S0167-5273(12)00938-2 [pii] -AID - 10.1016/j.ijcard.2012.07.001 [doi] -PST - ppublish -SO - Int J Cardiol. 2013 Feb 20;163(2):132-40. doi: 10.1016/j.ijcard.2012.07.001. Epub - 2012 Jul 21. - -PMID- 21437508 -OWN - NLM -STAT- MEDLINE -DCOM- 20111115 -LR - 20240718 -IS - 1806-9460 (Electronic) -IS - 1516-3180 (Print) -IS - 1516-3180 (Linking) -VI - 129 -IP - 1 -DP - 2011 Jan 6 -TI - Statins for progression of aortic valve stenosis and the best evidence for making - decisions in health care. -PG - 41-5 -LID - S1516-31802011000100008 [pii] -AB - In the Western world, calcified aortic valve stenosis is the most common form of - valvular heart disease, affecting up to 3% of adults over the age of 75 years. It - is a gradually progressive disease, characterized by a long asymptomatic phase - that may last for several decades, followed by a short symptomatic phase - associated with severe restriction of the valve orifice. Investigations on - treatments for aortic valve stenosis are still in progress. Thus, it is believed - that calcification of aortic valve stenosis is similar to the process of - atherosclerosis that occurs in coronary artery disease. Recent studies have - suggested that cholesterol lowering through the use of statins may have a - salutary effect on the progression of aortic valve stenosis. -FAU - Thiago, Luciana -AU - Thiago L -AD - Faculdade de Medicina de Marília, Marília, São Paulo, Brazil. - dralucianathiago@yahoo.com.br -FAU - Tsuj, Selma Rumiko -AU - Tsuj SR -FAU - Atallah, Alvaro Nagib -AU - Atallah AN -FAU - Puga, Maria Eduarda dos Santos -AU - Puga ME -FAU - de Góis, Aécio Flávio Teixeira -AU - de Góis AF -LA - eng -PT - Journal Article -PT - Review -PL - Brazil -TA - Sao Paulo Med J -JT - Sao Paulo medical journal = Revista paulista de medicina -JID - 100897261 -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Aortic Valve Stenosis/*drug therapy -MH - Calcinosis/*drug therapy -MH - Cholesterol, LDL/drug effects -MH - Disease Progression -MH - Evidence-Based Medicine -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -PMC - PMC10865912 -COIS- Conflict of interest: None -EDAT- 2011/03/26 06:00 -MHDA- 2011/11/16 06:00 -PMCR- 2011/01/06 -CRDT- 2011/03/26 06:00 -PHST- 2010/09/29 00:00 [received] -PHST- 2010/11/11 00:00 [accepted] -PHST- 2011/03/26 06:00 [entrez] -PHST- 2011/03/26 06:00 [pubmed] -PHST- 2011/11/16 06:00 [medline] -PHST- 2011/01/06 00:00 [pmc-release] -AID - S1516-31802011000100008 [pii] -AID - 10.1590/s1516-31802011000100008 [doi] -PST - ppublish -SO - Sao Paulo Med J. 2011 Jan 6;129(1):41-5. doi: 10.1590/s1516-31802011000100008. - -PMID- 21660911 -OWN - NLM -STAT- MEDLINE -DCOM- 20111013 -LR - 20110610 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 18 -IP - 3 -DP - 2011 -TI - Diastolic heart failure: predictors of mortality. -PG - 222-32 -AB - Diastolic heart failure (HF) as defined by the symptoms and signs of HF, - preserved ejection fraction and abnormal diastolic function is estimated to occur - in half of all patients presenting with HF. Patients with preserved ejection - fraction are older and more often female. The underlying etiology of HF differs, - with hypertension being more common in patients with preserved ejection fraction - and ischemic heart disease predominant among those with reduced ejection - fraction. Diastolic HF is associated with high mortality comparable with that of - HF with depressed ejection fraction with a five year survival rate after a first - episode of 43% and a higher excess mortality compared with the general - population. Despite significant disease burden, clinical and biological - prognostic factors in diastolic HF remain poorly understood. There is limited - data from well designed studies regarding the effective treatment strategies for - this group of patients. The purpose of this review is to summarize the mortality - data and predictors of mortality in patients with diastolic HF for better - understanding of the prognosis. In patients with diastolic HF older age, male - gender, non-Caucasian ethnicity, history of coronary artery disease and atrial - fibrillation are associated with poor prognosis. Anemia and B-type natriuretic - peptide are significant laboratory variable that predict mortality. Two - dimensional echocardiography and tissue Doppler imaging measurements including - left ventricular ejection fraction, E/Ea ratio ≥ 15, restrictive transmiral - filling (deceleration time £ 140 ms) and Em < 3.5 cm/s are predictors of adverse - outcomes in diastolic HF patients. -FAU - Sherazi, Saadia -AU - Sherazi S -AD - Department of Medicine, Unity Health System, Rochester, NY, USA. - ssherazi@unityhealth.org -FAU - Zaręba, Wojciech -AU - Zaręba W -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -SB - IM -MH - Heart Failure, Diastolic/diagnosis/*mortality/*physiopathology -MH - Humans -MH - Predictive Value of Tests -MH - Prognosis -MH - Risk Assessment/methods -MH - Risk Factors -MH - *Stroke Volume -EDAT- 2011/06/11 06:00 -MHDA- 2011/10/14 06:00 -CRDT- 2011/06/11 06:00 -PHST- 2011/06/11 06:00 [entrez] -PHST- 2011/06/11 06:00 [pubmed] -PHST- 2011/10/14 06:00 [medline] -PST - ppublish -SO - Cardiol J. 2011;18(3):222-32. - -PMID- 23470074 -OWN - NLM -STAT- MEDLINE -DCOM- 20130920 -LR - 20190907 -IS - 1873-4294 (Electronic) -IS - 1568-0266 (Linking) -VI - 13 -IP - 2 -DP - 2013 -TI - Myeloperoxidase: expressing inflammation and oxidative stress in cardiovascular - disease. -PG - 115-38 -AB - Myeloperoxidase (MPO), a heme protein released by leukocytes, is one of the most - widely studied during the last decades molecule that plays a crucial role in - inflammation and oxidative stress in the cellular level. It has become - increasingly recognized that MPO performs a very important role as part of the - innate immune system through the formation of microbicidal reactive oxidants, - whilst it affects the arterial endothelium with a number of mechanisms that - include modification of net cellular cholesterol flux and impairment of Nitric - Oxide (NO)-induced vascular relaxation. In that way, MPO is implicated into both - the formation and propagation of atheromatosis and there is substantial evidence - that it also promotes ischemia through destabilization of the vulnerable plaque. - Numerous studies have added information on the notion that MPO and its oxidant - products are part of the inflammatory cascade initiated by endothelial injury and - they are significantly overproduced at the site of arterial inflammation. - Subsequent studies achieved quantification of this observation showing - significant elevations of the systemic levels of MPO in a wide spectrum of - cardiovascular disease scenarios with acute coronary syndromes and heart failure - being the most studied. This review highlights key-aspects of MPO's - pathophysiological properties and summarizes the role of MPO as a diagnostic and - prognostic tool for a number of cardiovascular pathologies. -FAU - Anatoliotakis, Nikolaos -AU - Anatoliotakis N -AD - Cardiology Department and Cardiac Catheterization Laboratory, Athens General - Hospital G. Gennimatas, Athens, Greece. anatolmd@email.com -FAU - Deftereos, Spyridon -AU - Deftereos S -FAU - Bouras, Georgios -AU - Bouras G -FAU - Giannopoulos, Georgios -AU - Giannopoulos G -FAU - Tsounis, Dimitrios -AU - Tsounis D -FAU - Angelidis, Christos -AU - Angelidis C -FAU - Kaoukis, Andreas -AU - Kaoukis A -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Top Med Chem -JT - Current topics in medicinal chemistry -JID - 101119673 -RN - 0 (Biomarkers) -RN - 0 (Halogens) -RN - BBX060AN9V (Hydrogen Peroxide) -RN - EC 1.11.1.7 (Peroxidase) -SB - IM -MH - Animals -MH - Biomarkers/blood -MH - Cardiovascular Diseases/*metabolism/*physiopathology -MH - Endothelium, Vascular/metabolism/physiopathology -MH - Halogens/metabolism -MH - Heart Failure/metabolism/physiopathology -MH - Humans -MH - Hydrogen Peroxide/metabolism -MH - Hypertension/metabolism/physiopathology -MH - Inflammation/*metabolism/physiopathology -MH - Metabolic Syndrome/metabolism/physiopathology -MH - Oxidative Stress/*physiology -MH - Peroxidase/*blood/*physiology -MH - Predictive Value of Tests -MH - Prognosis -EDAT- 2013/03/09 06:00 -MHDA- 2013/09/21 06:00 -CRDT- 2013/03/09 06:00 -PHST- 2012/12/03 00:00 [received] -PHST- 2013/01/09 00:00 [revised] -PHST- 2013/01/28 00:00 [accepted] -PHST- 2013/03/09 06:00 [entrez] -PHST- 2013/03/09 06:00 [pubmed] -PHST- 2013/09/21 06:00 [medline] -AID - CTMC-EPUB-20130304-4 [pii] -AID - 10.2174/1568026611313020004 [doi] -PST - ppublish -SO - Curr Top Med Chem. 2013;13(2):115-38. doi: 10.2174/1568026611313020004. - -PMID- 18025521 -OWN - NLM -STAT- MEDLINE -DCOM- 20080118 -LR - 20161124 -IS - 1527-1323 (Electronic) -IS - 0271-5333 (Linking) -VI - 27 -IP - 6 -DP - 2007 Nov-Dec -TI - AAPM/RSNA physics tutorial for residents: Technologic advances in multidetector - CT with a focus on cardiac imaging. -PG - 1829-37 -AB - Cardiac computed tomography (CT) is emerging as an important tool for the - diagnosis and monitoring of heart disease. The prevalence of heart disease in the - United States is already quite high and is expected to increase as the "baby - boomer" segment of the population ages. To use complex multiple-row detector CT - scanners most efficiently for cardiac examinations, it is important to understand - many of the technical components. New developments in CT technology provide the - ability to examine the structure of the heart with a level of detail that was not - previously possible. In general, detector configurations have improved, the - number of channels has increased, and rotation speed has increased, resulting in - better quality of cardiac images. However, radiation dose for cardiac CT is - fairly high and demands constant vigilance. Several steps can be taken to reduce - the dose, including lowering the tube current as the x-ray beam crosses over - certain areas of the body, decreasing the tube current during certain phases of - the cardiac cycle, and using a higher pitch. Cardiac CT examination dose (for a - coronary artery study) is approximately equivalent to that of an abdominal-pelvic - CT examination or a dual-phase chest CT examination. -CI - RSNA, 2007 -FAU - Cody, Dianna D -AU - Cody DD -AD - Department of Imaging Physics, University of Texas M. D. Anderson Cancer Center, - 1515 Holcombe Blvd, Unit 56, Houston, TX 77030, USA. dcody@mdanderson.org -FAU - Mahesh, Mahadevappa -AU - Mahesh M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Radiographics -JT - Radiographics : a review publication of the Radiological Society of North - America, Inc -JID - 8302501 -SB - IM -MH - Equipment Design -MH - Heart Diseases/*diagnostic imaging -MH - Humans -MH - Image Processing, Computer-Assisted/instrumentation/*methods -MH - Internship and Residency/methods -MH - Phantoms, Imaging -MH - Radiation Dosage -MH - Radiography -MH - *Tomography Scanners, X-Ray Computed -RF - 14 -EDAT- 2007/11/21 09:00 -MHDA- 2008/01/19 09:00 -CRDT- 2007/11/21 09:00 -PHST- 2007/11/21 09:00 [pubmed] -PHST- 2008/01/19 09:00 [medline] -PHST- 2007/11/21 09:00 [entrez] -AID - 27/6/1829 [pii] -AID - 10.1148/rg.276075120 [doi] -PST - ppublish -SO - Radiographics. 2007 Nov-Dec;27(6):1829-37. doi: 10.1148/rg.276075120. - -PMID- 16612072 -OWN - NLM -STAT- MEDLINE -DCOM- 20061220 -LR - 20060816 -IS - 0008-6312 (Print) -IS - 0008-6312 (Linking) -VI - 106 -IP - 2 -DP - 2006 -TI - Congenital left ventricular aneurysms and diverticula: definition, - pathophysiology, clinical relevance and treatment. -PG - 63-72 -AB - A congenital left ventricular aneurysm or diverticulum is a rare cardiac - malformation; 411 cases have been reported since its first description in 1816, - and other cardiac, vascular or thoraco-abdominal abnormalities have been shown in - about 70%. It appears to be a developmental anomaly, starting in the 4th - embryonic week. Diagnosis can be made after exclusion of coronary artery disease, - local or systemic inflammation or traumatic causes as well as cardiomyopathies. - Clinically, most congenital left ventricular aneurysms and diverticula are - asymptomatic or may cause systemic embolization, heart failure, valvular - regurgitation, ventricular wall rupture, ventricular tachycardia or sudden - cardiac death. Diagnosis is established by imaging studies such as - echocardiography, magnetic resonance imaging or left ventricular angiography, - visualizing the structural changes and accompanying abnormalities. Mode of - treatment has to be individually tailored and depends on clinical presentation, - accompanying abnormalities and possible complications; treatment options include - surgical resection especially in symptomatic patients, anticoagulation after - systemic embolization, radiofrequency ablation or implantation of an implantable - cardioverter defibrillator in case of symptomatic ventricular tachycardia, - occasionally combined with class I or III antiarrhythmic drugs. -CI - Copyright 2006 S. Karger AG, Basel. -FAU - Ohlow, Marc-Alexander -AU - Ohlow MA -AD - Department of Cardiology, Heart Center, Zentralklinik Bad Berka, Germany. - m.ohlow.kar@zentralklinik-bad-berka.de -LA - eng -PT - Journal Article -PT - Review -DEP - 20060412 -PL - Switzerland -TA - Cardiology -JT - Cardiology -JID - 1266406 -SB - IM -MH - Diagnosis, Differential -MH - Diagnostic Imaging -MH - Electrocardiography -MH - Heart Aneurysm/diagnosis/*physiopathology/therapy -MH - Heart Defects, Congenital/diagnosis/*physiopathology/therapy -MH - Humans -MH - Incidence -MH - Prognosis -MH - *Ventricular Dysfunction, Left -RF - 123 -EDAT- 2006/04/14 09:00 -MHDA- 2006/12/21 09:00 -CRDT- 2006/04/14 09:00 -PHST- 2006/04/14 09:00 [pubmed] -PHST- 2006/12/21 09:00 [medline] -PHST- 2006/04/14 09:00 [entrez] -AID - 92634 [pii] -AID - 10.1159/000092634 [doi] -PST - ppublish -SO - Cardiology. 2006;106(2):63-72. doi: 10.1159/000092634. Epub 2006 Apr 12. - -PMID- 24084492 -OWN - NLM -STAT- MEDLINE -DCOM- 20141006 -LR - 20220317 -IS - 1876-4738 (Electronic) -IS - 0914-5087 (Linking) -VI - 63 -IP - 1 -DP - 2014 Jan -TI - Sleep apnea and cardiovascular risk. -PG - 3-8 -LID - S0914-5087(13)00252-9 [pii] -LID - 10.1016/j.jjcc.2013.08.009 [doi] -AB - Sleep apnea is evident in approximately 10% of adults in the general population, - but in certain cardiovascular diseases, and in particular those characterized by - sodium and water retention, its prevalence can exceed 50%. Although sleep apnea - is not as yet integrated into formal cardiovascular risk assessment algorithms, - there is increasing awareness of its importance in the causation or promotion of - hypertension, coronary artery disease, heart failure, atrial arrhythmias, and - stroke, and thus, not surprisingly, as a predictor of premature cardiovascular - death. Sleep apnea manifests as two principal phenotypes, both characterized by - respiratory instability: obstructive (OSA), which arises when sleep-related - withdrawal of respiratory drive to the upper airway dilator muscles is - superimposed upon a narrow and highly compliant airway predisposed to collapse, - and central (CSA), which occurs when the partial pressure of arterial carbon - dioxide falls below the apnea threshold, resulting in withdrawal of central drive - to respiratory muscles. The present objectives are to: (1) review the - epidemiology and patho-physiology of OSA and CSA, with particular emphasis on the - role of renal sodium retention in initiating and promoting these processes, and - on population studies that reveal the long-term consequences of untreated OSA and - CSA; (2) illustrate mechanical, autonomic, chemical, and inflammatory mechanisms - by which OSA and CSA can increase cardiovascular risk and event rates by - initiating or promoting hypertension, atherosclerosis, coronary artery disease, - heart failure, arrhythmias, and stroke; (3) highlight insights from randomized - trials in which treating sleep apnea was the specific target of therapy; (4) - emphasize the present lack of evidence that treating sleep apnea reduces - cardiovascular risk and the current clinical equipoise concerning treatment of - asymptomatic patients with sleep apnea; and (5) consider clinical implications - and future directions of clinical research and practice. -CI - Copyright © 2013. Published by Elsevier Ltd. -FAU - Floras, John S -AU - Floras JS -AD - University Health Network and Mount Sinai Hospital Division of Cardiology, - Canada; Faculty of Medicine, University of Toronto, Canada. Electronic address: - john.floras@utoronto.ca. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130929 -PL - Netherlands -TA - J Cardiol -JT - Journal of cardiology -JID - 8804703 -RN - 0 (Membrane Proteins) -RN - 0 (TMEM158 protein, human) -RN - 0 (Tumor Suppressor Proteins) -SB - IM -MH - Cardiovascular Diseases/*etiology/prevention & control -MH - Humans -MH - Membrane Proteins -MH - Positive-Pressure Respiration/methods -MH - Randomized Controlled Trials as Topic -MH - Sleep Apnea, Central/epidemiology/*etiology/physiopathology/therapy -MH - Sleep Apnea, Obstructive/epidemiology/*etiology/physiopathology/therapy -MH - Tumor Suppressor Proteins -OTO - NOTNLM -OT - Central sleep apnea -OT - Heart failure -OT - Hypertension -OT - Obstructive sleep apnea -OT - Sympathetic nervous system -EDAT- 2013/10/03 06:00 -MHDA- 2014/10/07 06:00 -CRDT- 2013/10/03 06:00 -PHST- 2013/08/23 00:00 [received] -PHST- 2013/08/24 00:00 [accepted] -PHST- 2013/10/03 06:00 [entrez] -PHST- 2013/10/03 06:00 [pubmed] -PHST- 2014/10/07 06:00 [medline] -AID - S0914-5087(13)00252-9 [pii] -AID - 10.1016/j.jjcc.2013.08.009 [doi] -PST - ppublish -SO - J Cardiol. 2014 Jan;63(1):3-8. doi: 10.1016/j.jjcc.2013.08.009. Epub 2013 Sep 29. - -PMID- 19346639 -OWN - NLM -STAT- MEDLINE -DCOM- 20090527 -LR - 20220211 -IS - 0019-5359 (Print) -IS - 0019-5359 (Linking) -VI - 63 -IP - 1 -DP - 2009 Jan -TI - Physical inactivity: a cardiovascular risk factor. -PG - 33-42 -AB - Evidence regarding health benefits of physical activity is overwhelming and plays - a critical role in both the primary and secondary prevention of coronary artery - disease (CAD). Epidemiological investigations show approximately half the - incidence of CAD in active compared to sedentary persons. A sedentary lifestyle - is considered by various national and international organizations to be one of - the most important modifiable risk factors for cardiovascular morbidity and - mortality. Fortunately, a moderate level of occupational or recreational activity - appears to confer a significant protective effect. Once coronary artery disease - has become manifest, exercise training can clearly improve the functional - capacity of patients and reduce overall mortality by decreasing the risk of - sudden death. Well-designed clinical investigations, supported by basic animal - studies, have demonstrated that the beneficial effects of exercise are related to - direct and indirect protective mechanisms. These benefits may result from an - improvement in cardiovascular risk factors, enhanced fibrinolysis, improved - endothelial function, decreased sympathetic tone, and other as-yet-undetermined - factors. Hence physical fitness, more than the absence of ponderosity or other - factors, is the major determinant of cardiovascular and metabolic risk and - long-term disease-free survival, in effect linking health span to life span. It - is obviously in every individual's interest to assume the responsibility for his - or her own health and embrace this extremely effective, safe, and inexpensive - treatment modality. The need for a comprehensive review of this particular topic - has arisen in view of the high prevalence of physical inactivity and overwhelming - evidence regarding CVD risk reduction with regular physical activity. -FAU - Prasad, D S -AU - Prasad DS -AD - Sudhir Heart Centre, Berhampur-760 002, Department of Community Medicine, Kalinga - Institute of Medical Sciences, Bhubaneshwar, Orissa, India. - sudhir_heartcare@hotmail.com -FAU - Das, B C -AU - Das BC -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian J Med Sci -JT - Indian journal of medical sciences -JID - 0373023 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/diagnosis/*epidemiology/genetics/*prevention & control -MH - Evidence-Based Medicine -MH - Exercise -MH - Genetic Predisposition to Disease -MH - Humans -MH - *Physical Fitness -MH - Primary Prevention/methods -MH - Risk Factors -MH - Secondary Prevention/methods -RF - 36 -EDAT- 2009/04/07 09:00 -MHDA- 2009/05/28 09:00 -CRDT- 2009/04/07 09:00 -PHST- 2009/04/07 09:00 [entrez] -PHST- 2009/04/07 09:00 [pubmed] -PHST- 2009/05/28 09:00 [medline] -PST - ppublish -SO - Indian J Med Sci. 2009 Jan;63(1):33-42. - -PMID- 20186041 -OWN - NLM -STAT- MEDLINE -DCOM- 20100618 -LR - 20100609 -IS - 1538-2990 (Electronic) -IS - 0002-9629 (Linking) -VI - 339 -IP - 6 -DP - 2010 Jun -TI - Dilated cardiomyopathy and role of antithrombotic therapy. -PG - 557-60 -LID - 10.1097/MAJ.0b013e3181cf048a [doi] -AB - BACKGROUND: There is no consensus as to whether anticoagulation has a favorable - risk:benefit in reducing thromboembolic events in patients with heart failure - (HF) secondary to dilated cardiomyopathy who do not suffer from atrial - fibrillation or primary valvular disease. METHODS AND RESULTS: The literature - reviewed on this topic included most recent and ongoing studies that assessed the - use of anticoagulation for this population. Several large retrospective studies - showed an increased risk of thromboembolic events among patients with depressed - left ventricular function. The relative risk of stroke in individuals with HF - from all causes was found to be 4.1 for men and 2.8 for women, but confounding - comorbidities (such as atrial fibrillation and coronary artery disease) were - commonly present. Currently, there are no randomized prospective trials to guide - the use of antithrombotics for these patients, and the risk of bleeding secondary - to anticoagulation has limited the use of oral anticoagulants for prevention of - thrombosis. Among patients with HF, increasing age directly correlates with both - major bleeding and thromboembolic events, with a 46% relative risk of bleeding - for each 10-year increase in age older than 40 years. CONCLUSIONS: To date, there - is no agreement on appropriate antithrombotic treatment (if any) for primary - thromboembolism prophylaxis in patients with dilated cardiomyopathy with sinus - rhythm. In recent years, several promising prospective trials were terminated - prematurely due to inadequate enrollment. The Warfarin Aspirin-Reduced Cardiac - Ejection Fraction trial may provide evidence regarding the use of anticoagulation - for patients with decreased myocardial function. -FAU - Abdo, Ashraf S -AU - Abdo AS -AD - Department of Medicine, University of Mississippi School of Medicine, Montgomery - VA Medical Center, Jackson, 39216, USA. ashraf.abdo@va.gov -FAU - Kemp, Rhonda -AU - Kemp R -FAU - Barham, Jennifer -AU - Barham J -FAU - Geraci, Stephen A -AU - Geraci SA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Med Sci -JT - The American journal of the medical sciences -JID - 0370506 -RN - 0 (Anticoagulants) -RN - 0 (Fibrinolytic Agents) -SB - IM -MH - Anticoagulants/adverse effects/*therapeutic use -MH - Blood Coagulation/drug effects -MH - Cardiomyopathy, Dilated/*blood/complications -MH - Fibrinolytic Agents/adverse effects/*therapeutic use -MH - Heart Failure/blood/complications -MH - Hemorrhage/chemically induced -MH - Humans -MH - Risk Assessment -MH - Thromboembolism/etiology/*prevention & control -RF - 39 -EDAT- 2010/02/27 06:00 -MHDA- 2010/06/19 06:00 -CRDT- 2010/02/27 06:00 -PHST- 2010/02/27 06:00 [entrez] -PHST- 2010/02/27 06:00 [pubmed] -PHST- 2010/06/19 06:00 [medline] -AID - S0002-9629(15)31580-9 [pii] -AID - 10.1097/MAJ.0b013e3181cf048a [doi] -PST - ppublish -SO - Am J Med Sci. 2010 Jun;339(6):557-60. doi: 10.1097/MAJ.0b013e3181cf048a. - -PMID- 16524540 -OWN - NLM -STAT- MEDLINE -DCOM- 20070924 -LR - 20191109 -IS - 1523-3782 (Print) -IS - 1523-3782 (Linking) -VI - 8 -IP - 2 -DP - 2006 Mar -TI - Imaging cardiac neuronal function and dysfunction. -PG - 131-8 -AB - In recent years, the importance of alterations of cardiac autonomic nerve - function in the pathophysiology of heart diseases including heart failure, - arrhythmia, ische-mic heart disease, and diabetes has been increasingly - recognized. Several radiolabeled compounds have been synthesized for noninvasive - imaging, including single photon emission CT and positron emission tomography - (PET). The catecholamine analogue I-123 metaiodobenzylguanidine (MIBG) is the - most commonly used tracer for mapping of myocardial presynaptic sympathetic - innervation on a broad clinical basis. In addition, radiolabeled catecholamines - and catecholamine analogues are available for PET imaging, which allows absolute - quantification and tracer kinetics modeling. Postsynaptic receptor PET imaging - added new insights into mechanisms of heart disease. These advanced imaging - techniques provide noninvasive, repeatable in vivo information of autonomic nerve - function in the human heart and are promising for providing profound insights - into molecular pathophysiology, monitoring of treatment, and determination of - individual outcome. -FAU - Higuchi, Takahiro -AU - Higuchi T -AD - Nuklearmedizinische Klinik und Poliklinik, Klinikum Rechts der Isar der - Technischen Universität München, Ismaninger Strasse 22, 81675 München, Germany. -FAU - Schwaiger, Markus -AU - Schwaiger M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -SB - IM -MH - Arrhythmias, Cardiac/diagnostic imaging/physiopathology -MH - Coronary Circulation -MH - Diabetic Neuropathies/diagnostic imaging/physiopathology -MH - Heart/*diagnostic imaging/*innervation -MH - Heart Diseases/*diagnostic imaging/physiopathology -MH - Heart Failure/diagnostic imaging/physiopathology -MH - Humans -MH - Myocardial Ischemia/diagnostic imaging/physiopathology -MH - Myocardium/pathology -MH - Parasympathetic Nervous System/*diagnostic imaging/physiology -MH - Positron-Emission Tomography/methods -MH - Sympathetic Nervous System/*diagnostic imaging/physiology -MH - Tomography, Emission-Computed, Single-Photon/methods -RF - 67 -EDAT- 2006/03/10 09:00 -MHDA- 2007/09/25 09:00 -CRDT- 2006/03/10 09:00 -PHST- 2006/03/10 09:00 [pubmed] -PHST- 2007/09/25 09:00 [medline] -PHST- 2006/03/10 09:00 [entrez] -AID - 10.1007/s11886-006-0024-z [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2006 Mar;8(2):131-8. doi: 10.1007/s11886-006-0024-z. - -PMID- 20333702 -OWN - NLM -STAT- MEDLINE -DCOM- 20100617 -LR - 20131121 -IS - 1522-726X (Electronic) -IS - 1522-1946 (Linking) -VI - 75 Suppl 1 -DP - 2010 Mar 1 -TI - Evidence-based management of patients undergoing PCI: contrast-induced acute - kidney injury. -PG - S15-20 -LID - 10.1002/ccd.22376 [doi] -AB - Contrast-induced acute kidney injury (CI-AKI) is one of the leading causes of - hospital-acquired acute kidney injury. CI-AKI is highly prevalent in patients - with well-known risk factors, including older age, chronic renal insufficiency, - congestive heart failure, and diabetes. Thus far, no strategies have been shown - to be effective in preventing CI-AKI beyond thorough patient selection, - minimizing the amount of contrast agent, and meticulous hydration of the patient. - The role of various drugs in preventing CI-AKI is still controversial and - warrants future studies. Despite the remaining uncertainty regarding the degree - of nephrotoxicity produced by various contrast agents, nonionic low-osmolar - contrast media may be preferred in patients at high risk for CI-AKI. -CI - (c) 2010 Wiley-Liss, Inc. -FAU - Caixeta, Adriano -AU - Caixeta A -AD - Columbia University Medical Center, Cardiovascular Research Foundation, New York, - New York 10022, USA. -FAU - Mehran, Roxana -AU - Mehran R -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Catheter Cardiovasc Interv -JT - Catheterization and cardiovascular interventions : official journal of the - Society for Cardiac Angiography & Interventions -JID - 100884139 -RN - 0 (Contrast Media) -RN - 0 (Protective Agents) -RN - 8MDF5V39QO (Sodium Bicarbonate) -RN - INU8H2KAWG (Fenoldopam) -RN - VTD58H1Z2X (Dopamine) -RN - WYQ7N0BPYC (Acetylcysteine) -SB - IM -MH - Acetylcysteine/administration & dosage -MH - Acute Disease -MH - *Angioplasty, Balloon, Coronary -MH - Contrast Media/*adverse effects -MH - Dopamine/administration & dosage -MH - Drug Administration Routes -MH - Evidence-Based Medicine -MH - Fenoldopam/administration & dosage -MH - Fluid Therapy -MH - Humans -MH - Kidney Diseases/chemically induced/*prevention & control -MH - Patient Selection -MH - Practice Guidelines as Topic -MH - Protective Agents/administration & dosage -MH - Radiography, Interventional/*adverse effects -MH - Risk Assessment -MH - Risk Factors -MH - Sodium Bicarbonate/administration & dosage -MH - Treatment Outcome -RF - 47 -EDAT- 2010/03/25 06:00 -MHDA- 2010/06/18 06:00 -CRDT- 2010/03/25 06:00 -PHST- 2010/03/25 06:00 [entrez] -PHST- 2010/03/25 06:00 [pubmed] -PHST- 2010/06/18 06:00 [medline] -AID - 10.1002/ccd.22376 [doi] -PST - ppublish -SO - Catheter Cardiovasc Interv. 2010 Mar 1;75 Suppl 1:S15-20. doi: 10.1002/ccd.22376. - -PMID- 22281067 -OWN - NLM -STAT- MEDLINE -DCOM- 20120918 -LR - 20120604 -IS - 1471-4973 (Electronic) -IS - 1471-4892 (Linking) -VI - 12 -IP - 2 -DP - 2012 Apr -TI - Animal models for studying vein graft failure and therapeutic interventions. -PG - 121-6 -LID - 10.1016/j.coph.2012.01.002 [doi] -AB - Vein grafts have been extensively used to bypass blockages in arteries, but are - themselves subject to early closure by thrombosis or later obstruction by vein - graft disease (neointimal hyperplasia and remodelling). Animal models are a - crucial means of testing potential therapeutic and surgical interventions to - prevent graft stenosis and occlusion. This review outlines many of the animal - models of vein grafting. Recent studies include targeted gene therapy to prevent - acute vein graft thrombosis and the use of folic acid to limit graft failure in - diabetic pigs. -CI - Copyright © 2012 Elsevier Ltd. All rights reserved. -FAU - Thomas, Anita C -AU - Thomas AC -AD - Bristol Heart Institute, University of Bristol, Bristol, BS2 8HW, United Kingdom. - a.thomas@bristol.ac.uk -LA - eng -GR - British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120124 -PL - England -TA - Curr Opin Pharmacol -JT - Current opinion in pharmacology -JID - 100966133 -SB - IM -MH - Animals -MH - *Coronary Artery Bypass -MH - Graft Occlusion, Vascular/*prevention & control -MH - *Models, Animal -MH - Neointima/prevention & control -MH - Thrombosis/prevention & control -MH - Veins/*transplantation -EDAT- 2012/01/28 06:00 -MHDA- 2012/09/19 06:00 -CRDT- 2012/01/28 06:00 -PHST- 2011/09/30 00:00 [received] -PHST- 2012/01/05 00:00 [accepted] -PHST- 2012/01/28 06:00 [entrez] -PHST- 2012/01/28 06:00 [pubmed] -PHST- 2012/09/19 06:00 [medline] -AID - S1471-4892(12)00003-3 [pii] -AID - 10.1016/j.coph.2012.01.002 [doi] -PST - ppublish -SO - Curr Opin Pharmacol. 2012 Apr;12(2):121-6. doi: 10.1016/j.coph.2012.01.002. Epub - 2012 Jan 24. - -PMID- 24479718 -OWN - NLM -STAT- MEDLINE -DCOM- 20141103 -LR - 20191112 -IS - 2212-4063 (Electronic) -IS - 1871-529X (Linking) -VI - 13 -IP - 3 -DP - 2013 Dec -TI - Contemporary risk assessment and cardiovascular outcomes in peripheral arterial - disease. -PG - 185-96 -AB - The term peripheral arterial disease (PAD) is often used to describe - atherosclerosis involving the arteries supplying the lower extremities. Risk - factors that predispose to the development and progression of both symptomatic - and asymptomatic PAD include age, ethnicity, smoking, diabetes mellitus, - hyperlipidemia, and hypertension. In addition, emerging biomarkers of - inflammation, oxidative stress, thrombosis and metabolism have also been - discovered to be predictive of future PAD events. Since traditional risk factors - for PAD predispose to the development of systemic atherosclerosis, identification - of PAD increases the likelihood of coexistent coronary heart and cerebrovascular - disease. Even after adjustment for risk factors, PAD appears to increase the risk - for ischemic manifestations involving these other vascular territories with about - a 2-fold increase in myocardial infarction and perhaps stroke. The most dramatic - consequence of PAD is impaired survival with a 2- to 3-fold increased risk of 5- - to 10-year mortality. Not only is the risk of adverse cardiovascular and - cerebrovascular complications elevated in patients with severe PAD, but it is - also markedly elevated in those with asymptomatic disease. The focus in the - management of PAD should be on early diagnosis and efforts to reduce the risk of - adverse events by risk factor modification and antiplatelet therapy. -FAU - Das, Jayanta R -AU - Das JR -FAU - Eberhardt, Robert T -AU - Eberhardt RT -AD - Boston Medical Center, 88 East Newton Street, C818, Boston, MA 02118, USA. - robert.eberhardt@bmc.org. -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Cardiovasc Hematol Disord Drug Targets -JT - Cardiovascular & hematological disorders drug targets -JID - 101269160 -SB - IM -MH - Age Factors -MH - Cardiovascular Diseases/*diagnosis -MH - Humans -MH - Peripheral Arterial Disease/*diagnosis -MH - Prognosis -MH - Risk Assessment -MH - Risk Factors -MH - Survival Analysis -EDAT- 2014/02/01 06:00 -MHDA- 2014/11/05 06:00 -CRDT- 2014/02/01 06:00 -PHST- 2012/05/25 00:00 [received] -PHST- 2013/06/24 00:00 [revised] -PHST- 2013/07/17 00:00 [accepted] -PHST- 2014/02/01 06:00 [entrez] -PHST- 2014/02/01 06:00 [pubmed] -PHST- 2014/11/05 06:00 [medline] -AID - CHDDT-58879 [pii] -AID - 10.2174/1871529x1303140129154241 [doi] -PST - ppublish -SO - Cardiovasc Hematol Disord Drug Targets. 2013 Dec;13(3):185-96. doi: - 10.2174/1871529x1303140129154241. - -PMID- 22262077 -OWN - NLM -STAT- MEDLINE -DCOM- 20120628 -LR - 20211021 -IS - 1614-0575 (Electronic) -IS - 1613-6071 (Print) -IS - 1613-6071 (Linking) -VI - 8 -IP - 3 -DP - 2011 Fall -TI - Fatty heart, cardiac damage, and inflammation. -PG - 403-17 -LID - 10.1900/RDS.2011.8.403 [doi] -AB - Type 2 diabetes and obesity are associated with systemic inflammation, - generalized enlargement of fat depots, and uncontrolled release of fatty acids - (FA) into the circulation. These features support the occurrence of cardiac - adiposity, which is characterized by an increase in intramyocardial triglyceride - content and an enlargement of the volume of fat surrounding the heart and - vessels. Both events may initially serve as protective mechanisms to portion - energy, but their excessive expansion can lead to myocardial damage and heart - disease. FA overload promotes FA oxidation and the accumulation of triglycerides - and metabolic intermediates, which can impair calcium signaling, β-oxidation, and - glucose utilization. This leads to damaged mitochondrial function and increased - production of reactive oxygen species, pro-apoptotic, and inflammatory molecules, - and finally to myocardial inflammation and dysfunction. Triglyceride accumulation - is associated with left ventricular hypertrophy and dysfunction. The enlargement - of epicardial fat in patients with metabolic disorders, and coronary artery - disease, is associated with the release of proinflammatory and proatherogenic - cytokines to the subtending tissues. In this review, we examine the evidence - supporting a causal relationship linking FA overload and cardiac dysfunction. - Also, we disentangle the separate roles of FA oxidation and triglyceride - accumulation in causing cardiac damage. Finally, we focus on the mechanisms of - inflammation development in the fatty heart, before summarizing the available - evidence in humans. Current literature confirms the dual (protective and - detrimental) role of cardiac fat, and suggests prospective studies to establish - the pathogenetic (when and how) and possible prognostic value of this potential - biomarker in humans. -CI - Copyright © by Lab & Life Press/SBDR -FAU - Guzzardi, Maria A -AU - Guzzardi MA -AD - Institute of Clinical Physiology, National Research Council (CNR), Via Moruzzi 1, - 56124 Pisa, Italy. -FAU - Iozzo, Patricia -AU - Iozzo P -LA - eng -PT - Journal Article -PT - Review -DEP - 20111110 -PL - Singapore -TA - Rev Diabet Stud -JT - The review of diabetic studies : RDS -JID - 101227575 -RN - 0 (Fatty Acids) -RN - 0 (Hypoglycemic Agents) -RN - 0 (Triglycerides) -SB - IM -MH - Adiposity -MH - Animals -MH - Diabetes Mellitus, Type 2/*complications/drug therapy -MH - Fatty Acids/*metabolism -MH - Heart/drug effects/physiopathology -MH - Heart Diseases/etiology/*immunology/metabolism/physiopathology -MH - Humans -MH - Hypoglycemic Agents/therapeutic use -MH - Triglycerides/*metabolism -PMC - PMC3280674 -EDAT- 2012/01/21 06:00 -MHDA- 2012/06/29 06:00 -PMCR- 2012/11/10 -CRDT- 2012/01/21 06:00 -PHST- 2012/01/21 06:00 [entrez] -PHST- 2012/01/21 06:00 [pubmed] -PHST- 2012/06/29 06:00 [medline] -PHST- 2012/11/10 00:00 [pmc-release] -AID - 10.1900/RDS.2011.8.403 [doi] -PST - ppublish -SO - Rev Diabet Stud. 2011 Fall;8(3):403-17. doi: 10.1900/RDS.2011.8.403. Epub 2011 - Nov 10. - -PMID- 23978350 -OWN - NLM -STAT- MEDLINE -DCOM- 20141006 -LR - 20220409 -IS - 1542-7714 (Electronic) -IS - 1542-3565 (Linking) -VI - 12 -IP - 3 -DP - 2014 Mar -TI - Risk of cerebrovascular accidents and ischemic heart disease in patients with - inflammatory bowel disease: a systematic review and meta-analysis. -PG - 382-93.e1: quiz e22 -LID - S1542-3565(13)01225-1 [pii] -LID - 10.1016/j.cgh.2013.08.023 [doi] -AB - BACKGROUND & AIMS: Inflammatory bowel disease (IBD) is associated with an - increased risk of venous thromboembolic disease. However, it is unclear whether - IBD modifies the risk of arterial thromboembolic events, including - cerebrovascular accidents (CVA) and ischemic heart disease (IHD). METHODS: We - performed a systematic review and meta-analysis of cohort and case-control - studies that reported incident cases of CVA and/or IHD in patients with IBD and a - non-IBD control population (or compared with a standardized population). We - calculated pooled odds ratios (ORs) with 95% confidence intervals (CIs). RESULTS: - We analyzed data from 9 studies (2424 CVA events in 5 studies, 6478 IHD events in - 6 studies). IBD was associated with a modest increase in the risk of CVA (5 - studies; OR, 1.18; 95% CI, 1.09-1.27), especially among women (4 studies; OR, - 1.28; 95% CI, 1.17-1.41) compared with men (OR, 1.11; 95% CI, 0.98-1.25), and in - young patients (<40-50 y old). The increase in risk was observed for patients - with Crohn's disease and in those with ulcerative colitis. IBD also was - associated with a 19% increase in the risk of IHD (6 studies; OR, 1.19; 95% CI, - 1.08-1.31), both in patients with Crohn's disease and ulcerative colitis. This - risk increase was seen primarily in women (4 studies; OR, 1.26; 95% CI, - 1.18-1.35) compared with men (OR, 1.05; 95% CI, 0.92-1.21), in young and old - patients. IBD was not associated with an increased risk of peripheral arterial - thromboembolic events. Considerable heterogeneity was observed in the overall - analysis. CONCLUSIONS: IBD is associated with a modest increase in the risk of - cardiovascular morbidity (from CVA and IHD)-particularly in women. These patients - should be counseled routinely on aggressive risk factor modification. -CI - Copyright © 2014 AGA Institute. Published by Elsevier Inc. All rights reserved. -FAU - Singh, Siddharth -AU - Singh S -AD - Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. -FAU - Singh, Harkirat -AU - Singh H -AD - Department of Internal Medicine, Thomas Jefferson University Hospital, - Philadelphia, Pennsylvania. -FAU - Loftus, Edward V Jr -AU - Loftus EV Jr -AD - Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. -FAU - Pardi, Darrell S -AU - Pardi DS -AD - Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. - Electronic address: pardi.darrell@mayo.edu. -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PT - Systematic Review -DEP - 20130824 -PL - United States -TA - Clin Gastroenterol Hepatol -JT - Clinical gastroenterology and hepatology : the official clinical practice journal - of the American Gastroenterological Association -JID - 101160775 -SB - IM -CIN - Clin Gastroenterol Hepatol. 2014 Dec;12(12):2134-5. doi: - 10.1016/j.cgh.2014.04.004. PMID: 24726904 -CIN - Clin Gastroenterol Hepatol. 2014 Dec;12(12):2135. doi: 10.1016/j.cgh.2014.07.001. - PMID: 24999155 -MH - Case-Control Studies -MH - Humans -MH - Inflammatory Bowel Diseases/*complications -MH - Myocardial Ischemia/*epidemiology -MH - Risk Assessment -MH - Risk Factors -MH - Sex Factors -MH - Stroke/*epidemiology -OTO - NOTNLM -OT - Coronary Artery Disease -OT - Inflammatory Bowel Disease -OT - Myocardial Infarction -OT - Stroke -EDAT- 2013/08/28 06:00 -MHDA- 2014/10/07 06:00 -CRDT- 2013/08/28 06:00 -PHST- 2013/05/31 00:00 [received] -PHST- 2013/07/31 00:00 [revised] -PHST- 2013/08/14 00:00 [accepted] -PHST- 2013/08/28 06:00 [entrez] -PHST- 2013/08/28 06:00 [pubmed] -PHST- 2014/10/07 06:00 [medline] -AID - S1542-3565(13)01225-1 [pii] -AID - 10.1016/j.cgh.2013.08.023 [doi] -PST - ppublish -SO - Clin Gastroenterol Hepatol. 2014 Mar;12(3):382-93.e1: quiz e22. doi: - 10.1016/j.cgh.2013.08.023. Epub 2013 Aug 24. - -PMID- 19367228 -OWN - NLM -STAT- MEDLINE -DCOM- 20090602 -LR - 20181201 -IS - 1530-6550 (Print) -IS - 1530-6550 (Linking) -VI - 10 -IP - 1 -DP - 2009 Winter -TI - Significant gastrointestinal bleeding in patients at risk of coronary stent - thrombosis. -PG - 14-24 -AB - The evolution of drug-eluting stents (DES), effective periprocedural - antithrombotic therapy, and advanced interventional techniques have fueled the - surge of percutaneous coronary interventions. Stent thrombosis remains a serious - complication of coronary artery stent implantation. Long-term antiplatelet - therapy is required to prevent stent thrombosis, especially following DES - implantation. Discontinuation of antiplatelet therapy (particularly clopidogrel) - is the strongest independent risk factor for the development of stent thrombosis. - Bleeding complications, most of which arise from the upper gastrointestinal (GI) - tract, are the major limiting factors for antiplatelet therapy. The association - of aspirin with the increased risk of upper GI bleeding has been well - established. Peptic ulcer bleeding and Helicobacter pylori infection are the 2 - most important risk factors for aspirin-associated GI bleeding complications. - Endoscopy (for both surveillance and potential intervention), performed either - emergently or semi-electively, is the primary tool for definitive management of - GI bleeding. Considering the increase in GI bleeding risk seen with prolonged - antiplatelet therapy, adjunctive proton pump inhibitor therapy and/or eradication - of H. pylori infection might be beneficial for DES patients on long-term - antiplatelet therapy. -FAU - Dai, Xuming -AU - Dai X -AD - Division of Cardiology, North Shore-Long Island Jewish Health System, New Hyde - Park, New York, USA. -FAU - Makaryus, Amgad N -AU - Makaryus AN -FAU - Makaryus, John N -AU - Makaryus JN -FAU - Jauhar, Rajiv -AU - Jauhar R -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - Singapore -TA - Rev Cardiovasc Med -JT - Reviews in cardiovascular medicine -JID - 100960007 -RN - 0 (Anti-Bacterial Agents) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Proton Pump Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Aged, 80 and over -MH - Angioplasty, Balloon, Coronary/adverse effects/instrumentation -MH - Anti-Bacterial Agents/therapeutic use -MH - Aspirin/adverse effects -MH - Clopidogrel -MH - Coronary Artery Disease/*therapy -MH - *Drug-Eluting Stents -MH - Duodenal Ulcer/*chemically induced/pathology/therapy -MH - Endoscopy, Gastrointestinal -MH - Female -MH - Helicobacter Infections/complications/microbiology -MH - Helicobacter pylori/pathogenicity -MH - Humans -MH - Peptic Ulcer Hemorrhage/*chemically induced/pathology/therapy -MH - Platelet Aggregation Inhibitors/*adverse effects -MH - Practice Guidelines as Topic -MH - Proton Pump Inhibitors/therapeutic use -MH - Risk Assessment -MH - Risk Factors -MH - Thrombosis/*etiology/prevention & control -MH - Ticlopidine/adverse effects/analogs & derivatives -MH - Treatment Outcome -RF - 75 -EDAT- 2009/04/16 09:00 -MHDA- 2009/06/03 09:00 -CRDT- 2009/04/16 09:00 -PHST- 2009/04/16 09:00 [entrez] -PHST- 2009/04/16 09:00 [pubmed] -PHST- 2009/06/03 09:00 [medline] -PST - ppublish -SO - Rev Cardiovasc Med. 2009 Winter;10(1):14-24. - -PMID- 21442576 -OWN - NLM -STAT- MEDLINE -DCOM- 20110920 -LR - 20161125 -IS - 1439-1902 (Electronic) -IS - 0171-6425 (Linking) -VI - 59 -IP - 4 -DP - 2011 Jun -TI - Left ventricular surgical remodeling after the STICH trial. -PG - 195-200 -LID - 10.1055/s-0030-1270738 [doi] -AB - Surgical treatment of anteroseptal scars has been, and still is, a challenging - task for cardiac surgeons. Most patients are in heart failure and the infarcted - areas can include different parts of the septum and the anterior wall. The core - problem of ischemic congestive heart failure is the undue demand placed on the - residual viable left ventricle myocardium. The surgical techniques used to - correct the mismatch between contractile and asynergic areas differ, but the - evolution of surgical techniques for left ventricular surgical remodeling (LVSR) - is still a work in progress. The most popular one was proposed by Dor et al. in - the 1980s and is still in general use. This technique addressed the problem of - recovering a predictable volume but not necessarily the problem of rebuilding a - physiologically conical shape. This anatomical aspect is becoming increasingly - important, and the purpose of septal reshaping, as proposed by us in 2004, is - more to recover a conical shape than to achieve volume reduction. Thus, we use - the Dor operation only when septoapical scars are present. The need for a - different surgical strategy is emphasized by the result of the STICH trial, which - reports the data of 1000 patients randomized for coronary artery bypass grafting - (CABG, n = 499) or CABG and LVSR (n = 501) and which failed to show any benefit - of LVSR. However, the only surgical technique used was the classic Dor operation, - where the purpose was to reestablish volume and not to recreate a physiological - shape. This study, however, does not provide a definitive answer, as - echocardiography results included only 212 patients in the CABG arm and 161 in - the CABG and LVSR arm. Furthermore, previous myocardial infarction (MI) was not a - prerequisite for study inclusion (13 % of patients in each group had no previous - MI) and whether a previous MI was Q-wave or not was not specified. In conclusion, - the long-term results after LVSR are satisfactory but appear to be better if a - conical shape has been recreated. The role of preemptive surgery in selected - cases and how to establish the limits of LVSR (grade of preoperative diastolic - dysfunction, diastolic diameter, ventricular volumes, function of the remote - zone, etc.) is still unclear. The impact of each individual treatment in the - individual patient (medical treatment, CABG alone, CABG and LVSR) has still to be - identified. -CI - © Georg Thieme Verlag KG Stuttgart · New York. -FAU - Calafiore, A M -AU - Calafiore AM -AD - Department of Adult Cardiac Center, Prince Sultan Cardiac Center, Riyadh, Saudi - Arabia. calafiore@unich.it -FAU - Iacò, A L -AU - Iacò AL -FAU - Abukoudair, W -AU - Abukoudair W -FAU - Penco, M -AU - Penco M -FAU - Di Mauro, M -AU - Di Mauro M -LA - eng -PT - Journal Article -PT - Review -DEP - 20110325 -PL - Germany -TA - Thorac Cardiovasc Surg -JT - The Thoracic and cardiovascular surgeon -JID - 7903387 -SB - IM -MH - *Cardiac Surgical Procedures/adverse effects/mortality -MH - Cicatrix/diagnostic imaging/etiology/mortality/*surgery -MH - Coronary Artery Bypass -MH - Disease-Free Survival -MH - Evidence-Based Medicine -MH - Heart Failure/diagnosis/etiology/mortality/*surgery -MH - Humans -MH - Myocardial Infarction/complications/diagnosis/mortality/*surgery -MH - Myocardium/*pathology -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - Risk Factors -MH - Survival Rate -MH - Suture Techniques -MH - Time Factors -MH - Treatment Outcome -MH - Ultrasonography -MH - *Ventricular Function, Left -MH - *Ventricular Remodeling -EDAT- 2011/03/29 06:00 -MHDA- 2011/09/21 06:00 -CRDT- 2011/03/29 06:00 -PHST- 2011/03/29 06:00 [entrez] -PHST- 2011/03/29 06:00 [pubmed] -PHST- 2011/09/21 06:00 [medline] -AID - 10.1055/s-0030-1270738 [doi] -PST - ppublish -SO - Thorac Cardiovasc Surg. 2011 Jun;59(4):195-200. doi: 10.1055/s-0030-1270738. Epub - 2011 Mar 25. - -PMID- 18953278 -OWN - NLM -STAT- MEDLINE -DCOM- 20081113 -LR - 20101118 -IS - 1530-6550 (Print) -IS - 1530-6550 (Linking) -VI - 9 -IP - 3 -DP - 2008 Summer -TI - The relationship between erectile dysfunction and cardiovascular disease. Part - II: The role of PDE-5 inhibition in sexual dysfunction and cardiovascular - disease. -PG - 187-95 -AB - Erectile dysfunction (ED) is a sensitive indicator of wider arterial - insufficiency and an early correlate for the presence of ischemic heart disease. - Among patients with coronary artery disease, prevalence reports of ED range from - 42% to 75%. The US Food and Drug Administration has approved 3 - phosphodiesterase-5 (PDE-5) inhibitors for treatment of male sexual dysfunction: - sildenafil, tadalafil, and vardenafil. PDE-5 inhibitors also have cardiovascular - effects. They inhibit PDE-5 enzymes in pulmonary vasculature, which causes - vasodilation that decreases pulmonary vascular pressure. Sildenafil is approved - for treatment of patients with pulmonary hypertension. PDE-5 inhibition with - sildenafil improves cardiac output by balancing pulmonary and systemic - vasodilation, and augments and prolongs the hemodynamic effects of inhaled nitric - oxide in patients with chronic congestive heart failure and pulmonary - hypertension. In vivo and in vitro studies are examining the possible beneficial - effects of PDE-5 inhibitors in conditions such as myocardial infarction and - endothelial dysfunction. -FAU - Kapur, Vishal -AU - Kapur V -AD - Division of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, - USA. -FAU - Chien, Christopher V -AU - Chien CV -FAU - Fuess, Justin E -AU - Fuess JE -FAU - Schwarz, Ernst R -AU - Schwarz ER -LA - eng -PT - Journal Article -PT - Review -PL - Singapore -TA - Rev Cardiovasc Med -JT - Reviews in cardiovascular medicine -JID - 100960007 -RN - 0 (Cardiovascular Agents) -RN - 0 (Phosphodiesterase 5 Inhibitors) -RN - 0 (Phosphodiesterase Inhibitors) -RN - EC 3.1.4.35 (Cyclic Nucleotide Phosphodiesterases, Type 5) -SB - IM -MH - Cardiovascular Agents/adverse effects/*therapeutic use -MH - Cardiovascular Diseases/complications/*drug therapy/enzymology -MH - Cyclic Nucleotide Phosphodiesterases, Type 5/metabolism -MH - Erectile Dysfunction/*drug therapy/enzymology/etiology -MH - Heart Failure/drug therapy/enzymology -MH - Humans -MH - Hypertension, Pulmonary/drug therapy/enzymology -MH - Male -MH - Myocardial Ischemia/drug therapy/enzymology -MH - *Phosphodiesterase 5 Inhibitors -MH - Phosphodiesterase Inhibitors/adverse effects/*therapeutic use -MH - Treatment Outcome -RF - 60 -EDAT- 2008/10/28 09:00 -MHDA- 2008/11/14 09:00 -CRDT- 2008/10/28 09:00 -PHST- 2008/10/28 09:00 [pubmed] -PHST- 2008/11/14 09:00 [medline] -PHST- 2008/10/28 09:00 [entrez] -PST - ppublish -SO - Rev Cardiovasc Med. 2008 Summer;9(3):187-95. - -PMID- 21626163 -OWN - NLM -STAT- MEDLINE -DCOM- 20130405 -LR - 20220408 -IS - 1573-7322 (Electronic) -IS - 1382-4147 (Linking) -VI - 17 -IP - 3 -DP - 2012 May -TI - Diabetic cardiomyopathy: understanding the molecular and cellular basis to - progress in diagnosis and treatment. -PG - 325-44 -LID - 10.1007/s10741-011-9257-z [doi] -AB - Diabetes mellitus is an important and prevalent risk factor for congestive heart - failure. Diabetic cardiomyopathy has been defined as ventricular dysfunction that - occurs in diabetic patients independent of a recognized cause such as coronary - artery disease or hypertension. The disease course consists of a hidden - subclinical period, during which cellular structural insults and abnormalities - lead initially to diastolic dysfunction, later to systolic dysfunction, and - eventually to heart failure. Left ventricular hypertrophy, metabolic - abnormalities, extracellular matrix changes, small vessel disease, cardiac - autonomic neuropathy, insulin resistance, oxidative stress, and apoptosis are the - most important contributors to diabetic cardiomyopathy onset and progression. - Hyperglycemia is a major etiological factor in the development of diabetic - cardiomyopathy. It increases the levels of free fatty acids and growth factors - and causes abnormalities in substrate supply and utilization, calcium - homeostasis, and lipid metabolism. Furthermore, it promotes excessive production - and release of reactive oxygen species, which induces oxidative stress leading to - abnormal gene expression, faulty signal transduction, and cardiomyocytes - apoptosis. Stimulation of connective tissue growth factor, fibrosis, and the - formation of advanced glycation end-products increase the stiffness of the - diabetic hearts. Despite all the current information on diabetic cardiomyopathy, - translational research is still scarce due to limited human myocardial tissue and - most of our knowledge is extrapolated from animals. This paper aims to elucidate - some of the molecular and cellular pathophysiologic mechanisms, structural - changes, and therapeutic strategies that may help struggle against diabetic - cardiomyopathy. -FAU - Falcão-Pires, Inês -AU - Falcão-Pires I -AD - Department of Physiology and Cardiothoracic Surgery, Cardiovascular R&D Unit, - University of Porto, Porto, Portugal. -FAU - Leite-Moreira, Adelino F -AU - Leite-Moreira AF -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -SB - IM -MH - Diabetic Cardiomyopathies/complications/metabolism/*physiopathology -MH - Humans -MH - Hyperglycemia/*complications/metabolism/therapy -MH - Insulin Resistance/*physiology -MH - Myocytes, Cardiac/*metabolism/pathology -MH - Oxidative Stress/physiology -MH - Ventricular Dysfunction -EDAT- 2011/06/01 06:00 -MHDA- 2013/04/06 06:00 -CRDT- 2011/06/01 06:00 -PHST- 2011/06/01 06:00 [entrez] -PHST- 2011/06/01 06:00 [pubmed] -PHST- 2013/04/06 06:00 [medline] -AID - 10.1007/s10741-011-9257-z [doi] -PST - ppublish -SO - Heart Fail Rev. 2012 May;17(3):325-44. doi: 10.1007/s10741-011-9257-z. - -PMID- 19785385 -OWN - NLM -STAT- MEDLINE -DCOM- 20091021 -LR - 20100309 -IS - 0042-773X (Print) -IS - 0042-773X (Linking) -VI - 55 -IP - 9 -DP - 2009 Sep -TI - [Target values in hypertension treatment. Will they apply in older patients with - hypertension, diabetics and in patients with IHD?]. -PG - 833-40 -AB - The incidence of isolated systolic hypertension increases with age since 50 - years. Systolic pressure appears to have higher prognostic importance than - diastolic pressure in patients older than 50 years. Treatment of isolated - systolic hypertension importantly decreases cerebrovascular events, coronary - events as well as overall mortality. Studies providing the relevant evidence have - mostly been conducted at the beginning of 1990s. The baseline systolic pressure - in all these studies was 160 mmHg and higher. This is because the isolated - systolic hypertension then was defined as systolic pressure of 160 mmHg or higher - and diastolic hypertension as pressure of 95 mmHg or higher. No study confirming - that systolic pressure lowering to the range of 140-159 mmHg in older patients - would positively affect morbidity and mortality, with a further aim to achieve - systolic pressure levels of less than 140 mmHg, have been conducted so far. The - recommendation to aim, even in older patients, for the target values of less than - 140 mmHg is based mainly on observational studies. Possible existence of the - diastolic pressure J-curve in patients with ischemic heart disease represents - another unresolved issue. There is a lack of randomised studies on this subject - comparing reduction of the diastolic pressure to below 80, below 70 mmHg and - below 60 mm Hg. The joint guidelines of the European Society of Hypertension and - European Society of Cardiology recommend the target value of <140/90 mmHg for the - treatment of isolated systolic hypertension, and systolic pressure of less than - 130 mmHg in patients with diabetes, cardiovascular or renal diseases (following - myocardial infarction, cerebrovascular event or renal dysfunction), in patients - with metabolic syndrome and in patients with the overall cardiovascular - SCORE-based risk of > or = 5%. There are no data available confirming that - lowering blood pressure to these target values is justified. The 'lower the blood - pressure is better' rule applies to cerebrovascular events only. The data from - the large ONTARGET study show that lowering of the systolic blood pressure to - less than 130 mmHg does not bring any benefit to hypertonics with high - cardiovascular risk, except from cerebrovascular events. The J-curve exists for - cardiovascular mortality, myocardial infarction and probably also for diabetics, - with the turning point at about 130 mmHg. Further reduction of blood pressure - increases cardiovascular mortality and myocardial infarctions. We believe that, - in the current atmosphere of contradictory data on the diastolic pressure and - coronary events relationship J-curve, caution is needed in older patients with - isolated systolic hypertension and IHD in cases when the on-treatment diastolic - pressure falls below 70 mmHg. In such a situation we would not insist on reaching - the systolic pressure target value. We believe that this should apply to older - patients with ischemic heart disease in particular. In summary, it is possible to - conclude that hypertension treatment target blood pressure values of less than - 140/90 mmHg are justified. However, target values of less than 130/80 mmHg in - diabetics, in patients with a cardiovascular disease and in other patient groups - (metabolic syndrome, overall cardiovascular risk of 5% or higher) are challenged - by the results of a range of large studies, and verification in prospective - studies is of utmost importance. -FAU - Widimský, J -AU - Widimský J -AD - Klinika kardiologie IKEM Praha. widimsky@seznam.cz -LA - cze -PT - English Abstract -PT - Journal Article -PT - Review -TT - Cílové hodnoty lécby hypertenze. Budou platit i u starsích hypertoniků, diabetiků - a u pacientů s ICHS? -PL - Czech Republic -TA - Vnitr Lek -JT - Vnitrni lekarstvi -JID - 0413602 -SB - IM -CIN - Vnitr Lek. 2009 Dec;55(12):1193-5. PMID: 20070036 -MH - Blood Pressure -MH - *Diabetes Complications -MH - Humans -MH - Hypertension/complications/*drug therapy/physiopathology -MH - Myocardial Ischemia/*complications -RF - 35 -EDAT- 2009/09/30 06:00 -MHDA- 2009/10/22 06:00 -CRDT- 2009/09/30 06:00 -PHST- 2009/09/30 06:00 [entrez] -PHST- 2009/09/30 06:00 [pubmed] -PHST- 2009/10/22 06:00 [medline] -PST - ppublish -SO - Vnitr Lek. 2009 Sep;55(9):833-40. - -PMID- 20099712 -OWN - NLM -STAT- MEDLINE -DCOM- 20100218 -LR - 20250623 -IS - 0966-8519 (Print) -IS - 0966-8519 (Linking) -VI - 18 -IP - 6 -DP - 2009 Nov -TI - Evaluation of aortic valve stenosis by cardiac multislice computed tomography - compared with echocardiography: a systematic review and meta-analysis. -PG - 634-43 -AB - BACKGROUND AND AIM OF THE STUDY: It has not yet been established whether - multi-slice computed tomography (MSCT) is reliable for the quantification of - aortic valve area (AVA) in patients with aortic valve stenosis (AVS) and - simultaneously for assessment of the coronary anatomy. The study aim, via a - systematic literature review and meta-analysis, was to explore whether MSCT is a - reliable method for AVA quantification, and simultaneously to assess the coronary - anatomy in patients with AVS. METHODS: A comprehensive systematic literature - search and meta-analysis was conducted that included 14 studies totaling 470 - patients. The meta-analysis was carried out to examine the reliability of MSCT - compared to transthoracic echocardiography (TTE) and transesophageal - echocardiography (TEE). Seven studies including 266 patients with AVS were also - eligible for a secondary analysis to compare the accuracy of MSCT with invasive - coronary angiography. RESULTS: The AVA was measured by MSCT and TTE in all 14 - studies, and by TEE in four studies. The results of the meta-analyses showed that - planimetry by MSCT overestimated the AVA, with a bias of 0.08 (95% CI 0.04, 0.13) - cm2) (p = 0.0001) compared to TTE. The MSCT measurement was concordant with - planimetry by TEE, with a small bias of -0.02 (95% CI -0.16, 0.11) cm2 (p = - 0.71). MSCT, when compared to invasive angiography for the detection of - significant coronary stenosis, showed sensitivity, specificity and diagnostic - odds ratio of 95.5% (95% CI 88-99), 81% (95% CI 75-86)%, and 53 (95% CI 19-147), - respectively. CONCLUSION: MSCT is a reliable method for the quantification of - AVA, and represents a promising technique for the combined evaluation of aortic - valve morphology and coronary artery disease. -FAU - Abdulla, Jawdat -AU - Abdulla J -AD - Division of Cardiology, Department of Medicine, Glostrup University Hospital, - Copenhagen, Denmark. jawab@dadlnet.dk -FAU - Sivertsen, Jacob -AU - Sivertsen J -FAU - Kofoed, Klaus Fuglsang -AU - Kofoed KF -FAU - Alkadhi, Hatem -AU - Alkadhi H -FAU - LaBounty, Troy -AU - LaBounty T -FAU - Abildstrom, Steen Z -AU - Abildstrom SZ -FAU - Kober, Lars -AU - Kober L -FAU - Christensen, Erik -AU - Christensen E -FAU - Torp-Pedersen, Christian -AU - Torp-Pedersen C -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -PL - England -TA - J Heart Valve Dis -JT - The Journal of heart valve disease -JID - 9312096 -SB - IM -MH - Angiography -MH - Aortic Valve Stenosis/*diagnostic imaging -MH - Echocardiography -MH - Humans -MH - Tomography, X-Ray Computed -RF - 48 -EDAT- 2010/01/27 06:00 -MHDA- 2010/02/19 06:00 -CRDT- 2010/01/27 06:00 -PHST- 2010/01/27 06:00 [entrez] -PHST- 2010/01/27 06:00 [pubmed] -PHST- 2010/02/19 06:00 [medline] -PST - ppublish -SO - J Heart Valve Dis. 2009 Nov;18(6):634-43. - -PMID- 19185627 -OWN - NLM -STAT- MEDLINE -DCOM- 20090224 -LR - 20250623 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 157 -IP - 2 -DP - 2009 Feb -TI - Health status as a risk factor in cardiovascular disease: a systematic review of - current evidence. -PG - 208-18 -LID - 10.1016/j.ahj.2008.09.020 [doi] -AB - BACKGROUND: Patient-perceived health status is receiving increased recognition as - a patient-centered outcome in chronic heart failure (CHF) and coronary artery - disease (CAD), but poor health status is also associated with adverse prognosis. - In this systematic review, we examined current evidence on the influence of - health status on prognosis in CHF and CAD. METHODS: We conducted a search of - PubMed using a set of a priori-defined search terms, the Web of Science for newly - cited articles, and the reference lists of eligible articles, resulting in 34 - articles. RESULTS: Poor physical health status was a significant predictor for - adverse health outcomes in patients with CHF and CAD. In CHF, poor physical - health status seemed to be a stronger predictor of hospitalization than - mortality. Little evidence was found that poor mental health status is associated - with adverse prognosis in CHF and CAD. A disease-specific measure was a better - predictor in CHF, but not in CAD. The majority of studies adjusted for an - objective measure of disease severity. Neither the index event nor time to - follow-up appeared to influence the predictive value of health status. - CONCLUSIONS: Poor physical health status is associated with adverse CAD and CHF - prognosis. Heterogeneity across studies makes definitive conclusions difficult as - to which components of health status may be detrimental to patients' health, and - how health status as a potential risk factor should be assessed, monitored, and - intervened upon in clinical practice. -FAU - Mommersteeg, Paula M C -AU - Mommersteeg PM -AD - Center of Research on Psychology in Somatic Diseases, Tilburg University, The - Netherlands. -FAU - Denollet, Johan -AU - Denollet J -FAU - Spertus, John A -AU - Spertus JA -FAU - Pedersen, Susanne S -AU - Pedersen SS -LA - eng -PT - Journal Article -PT - Systematic Review -DEP - 20081219 -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -SB - IM -MH - *Cardiovascular Diseases -MH - *Health Status -MH - Humans -MH - Prognosis -MH - Risk Factors -RF - 47 -EDAT- 2009/02/03 09:00 -MHDA- 2009/02/25 09:00 -CRDT- 2009/02/03 09:00 -PHST- 2008/07/25 00:00 [received] -PHST- 2008/09/26 00:00 [accepted] -PHST- 2009/02/03 09:00 [entrez] -PHST- 2009/02/03 09:00 [pubmed] -PHST- 2009/02/25 09:00 [medline] -AID - S0002-8703(08)00826-0 [pii] -AID - 10.1016/j.ahj.2008.09.020 [doi] -PST - ppublish -SO - Am Heart J. 2009 Feb;157(2):208-18. doi: 10.1016/j.ahj.2008.09.020. Epub 2008 Dec - 19. - -PMID- 20705170 -OWN - NLM -STAT- MEDLINE -DCOM- 20100914 -LR - 20161125 -IS - 1557-8275 (Electronic) -IS - 0033-8389 (Linking) -VI - 48 -IP - 4 -DP - 2010 Jul -TI - Evaluation of the patient with acute chest pain. -PG - 745-55 -LID - 10.1016/j.rcl.2010.05.003 [doi] -AB - The past decade has brought rapid advances in CT technology, which allows - increasingly precise application to the study of coronary arteries and acute - chest pain. The literature has expanded to lend quantifiable justification to the - intuitive appeal of a rapid, reproducible, 3D study of the heart and vasculature. - More complete analysis of efficacy and costs on broader populations will further - refine our understanding of how best to implement what may become the new gold - standard. Meanwhile, evolving technology promises to further challenge - radiologists and clinicians to optimize approach and diagnosis to acute chest - pain. -CI - 2010 Elsevier Inc. All rights reserved. -FAU - Goldberg, Ari -AU - Goldberg A -AD - Department of Radiology, Hospital of the University of Pennsylvania, - Philadelphia, 19104, USA. ari.goldberg@uphs.upenn.edu -FAU - Litt, Harold I -AU - Litt HI -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Radiol Clin North Am -JT - Radiologic clinics of North America -JID - 0123703 -SB - IM -MH - Acute Disease -MH - Cardiovascular Diseases/*diagnostic imaging -MH - Chest Pain/*diagnostic imaging -MH - Diagnosis, Differential -MH - Humans -MH - Radiography, Thoracic/methods -MH - Tomography, X-Ray Computed/*methods -RF - 66 -EDAT- 2010/08/14 06:00 -MHDA- 2010/09/16 06:00 -CRDT- 2010/08/14 06:00 -PHST- 2010/08/14 06:00 [entrez] -PHST- 2010/08/14 06:00 [pubmed] -PHST- 2010/09/16 06:00 [medline] -AID - S0033-8389(10)00072-2 [pii] -AID - 10.1016/j.rcl.2010.05.003 [doi] -PST - ppublish -SO - Radiol Clin North Am. 2010 Jul;48(4):745-55. doi: 10.1016/j.rcl.2010.05.003. - -PMID- 24049399 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140218 -LR - 20211021 -IS - 0974-8520 (Print) -IS - 0976-9382 (Electronic) -IS - 0974-8520 (Linking) -VI - 34 -IP - 1 -DP - 2013 Jan -TI - Medohara and Lekhaniya dravyas (anti-obesity and hypolipidemic drugs) in - Ayurvedic classics: A critical review. -PG - 11-6 -LID - 10.4103/0974-8520.115437 [doi] -AB - Santarpanottha Vikaras (diseases due to excessive nutrition) are increasing - during current times. Medodushti (disorders of fat metabolism) serves as one of - the important etiological factor in most of these disorders including Ischemic - Heart Disease (IHD). IHD is identified as one of the leading cause of morbidity - and mortality worldwide in both developing and developed countries. Retention and - deposition of serum lipids resulting in decreased flow of blood in coronary - arteries being the underlying cause. Conventional and herbal drugs are being used - to lower levels of serum cholesterol to prevent this menace. In this regard, an - attempt has been made to critically review the Medohara and Lekhaniya - (Anti-obesity and Hypolipidemic) drugs mentioned in Ganas (group of drugs) of - Ayurvedic classical texts which may abet our understanding of prevention and - management of conditions like Dyslipidemia and its complications. Administration - of drugs possessing Tikta Rasa (bitter taste), Ushna Veerya (hot in potency), - Laghu and Ruksha Guna (light and dry qualities), Katu Vipaka and Vata Kaphahara - actions were noted during the analysis. -FAU - Kumari, Harshitha -AU - Kumari H -AD - PhD Scholar, Department of Dravyaguna, Institute for Post Graduate Teaching and - Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India. -FAU - Pushpan, Reshmi -AU - Pushpan R -FAU - Nishteswar, K -AU - Nishteswar K -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Ayu -JT - Ayu -JID - 7605807 -PMC - PMC3764867 -OTO - NOTNLM -OT - Dyslipidemia -OT - Lekhana -OT - Medohara -OT - herbs -OT - obesity -EDAT- 2013/09/21 06:00 -MHDA- 2013/09/21 06:01 -PMCR- 2013/01/01 -CRDT- 2013/09/20 06:00 -PHST- 2013/09/20 06:00 [entrez] -PHST- 2013/09/21 06:00 [pubmed] -PHST- 2013/09/21 06:01 [medline] -PHST- 2013/01/01 00:00 [pmc-release] -AID - AYU-34-11 [pii] -AID - 10.4103/0974-8520.115437 [doi] -PST - ppublish -SO - Ayu. 2013 Jan;34(1):11-6. doi: 10.4103/0974-8520.115437. - -PMID- 17176844 -OWN - NLM -STAT- MEDLINE -DCOM- 20070126 -LR - 20061220 -IS - 2522-9028 (Print) -IS - 2522-9028 (Linking) -VI - 52 -IP - 5 -DP - 2006 -TI - [Physiological aspects of ubiquinone supplementation in cardiovascular - pathology]. -PG - 80-91 -AB - Ubiquinone (coenzyme Q10) is an obligatory component of the respiratory chain in - the inner mitochondrial membrane coupled to ATP synthesis and acts as an - antioxidant. Its additional localization in the different subcellular fractions - is probably associated with its multiple functions in the cell. Coenzyme Q10 - deficiency has been observed in patients with congestive heart failure, angina - pectoris, coronary artery disease, cardiomyopathy, hypertension, mitral valve - prolapse. The clinical benefits of Q10 supplementation in prevention and - treatment of cardiovascular diseases have been observed in many trials. - Ubiquinone is the introduction of the metabolic drugs and may be recommended to - patients with cardiovascular pathologies as an adjunct to conventional treatment. -FAU - Kuchmenko, O B -AU - Kuchmenko OB -LA - ukr -PT - English Abstract -PT - Journal Article -PT - Review -PL - Ukraine -TA - Fiziol Zh (1994) -JT - Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) -JID - 9601541 -RN - 1339-63-5 (Ubiquinone) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*drug therapy/metabolism/prevention & control -MH - Energy Metabolism/drug effects -MH - Humans -MH - Mitochondria/drug effects/metabolism -MH - Myocardium/metabolism -MH - *Ubiquinone/administration & dosage/physiology/therapeutic use -RF - 69 -EDAT- 2006/12/21 09:00 -MHDA- 2007/01/27 09:00 -CRDT- 2006/12/21 09:00 -PHST- 2006/12/21 09:00 [pubmed] -PHST- 2007/01/27 09:00 [medline] -PHST- 2006/12/21 09:00 [entrez] -PST - ppublish -SO - Fiziol Zh (1994). 2006;52(5):80-91. - -PMID- 17191303 -OWN - NLM -STAT- MEDLINE -DCOM- 20070305 -LR - 20181113 -IS - 0513-5796 (Print) -IS - 1976-2437 (Electronic) -IS - 0513-5796 (Linking) -VI - 47 -IP - 6 -DP - 2006 Dec 31 -TI - Kawasaki disease. -PG - 759-72 -AB - Kawasaki disease is an acute febrile, systemic vasculitic syndrome of an unknown - etiology that primarily occurs in children younger than five years of age. The - principal presentations of Kawasaki disease include fever, bilateral nonexudative - conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, - rash, and cervical lymphadenopathy. Coronary artery aneurysms or ectasia develops - in 15% to 25% of untreated children with the disease, which may later lead to - myocardial infarction, sudden death, or ischemic heart disease. Treatment with - intravenous gamma globulin (IVIG) is effective, but the mode of action is still - unclear. The development of a diagnostic test, a more specific therapy, and - ultimately the prevention of this potentially fatal illness in children are all - dependent upon the continued advances in determining the etiopathogenesis of this - fascinating disorder. -FAU - Kim, Dong Soo -AU - Kim DS -AD - Division of Infectious Disease and Immunology, Department of Pediatrics, Yonsei - University College of Medicine, Severance Children's Hospital, Seoul, Korea. - dskim6634@yumc.yonsei.ac.kr -LA - eng -PT - Journal Article -PT - Review -PL - Korea (South) -TA - Yonsei Med J -JT - Yonsei medical journal -JID - 0414003 -RN - 0 (Glucocorticoids) -RN - 0 (Immunoglobulins, Intravenous) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Aspirin/therapeutic use -MH - Cardiovascular Diseases/diagnosis/drug therapy/etiology -MH - Child, Preschool -MH - Glucocorticoids/therapeutic use -MH - Humans -MH - Immunoglobulins, Intravenous/therapeutic use -MH - Mucocutaneous Lymph Node Syndrome/*diagnosis/drug therapy/epidemiology/etiology -MH - Prognosis -MH - Treatment Failure -PMC - PMC2687814 -EDAT- 2006/12/28 09:00 -MHDA- 2007/03/06 09:00 -PMCR- 2006/12/31 -CRDT- 2006/12/28 09:00 -PHST- 2006/12/28 09:00 [pubmed] -PHST- 2007/03/06 09:00 [medline] -PHST- 2006/12/28 09:00 [entrez] -PHST- 2006/12/31 00:00 [pmc-release] -AID - 200612759 [pii] -AID - 10.3349/ymj.2006.47.6.759 [doi] -PST - ppublish -SO - Yonsei Med J. 2006 Dec 31;47(6):759-72. doi: 10.3349/ymj.2006.47.6.759. - -PMID- 19475877 -OWN - NLM -STAT- MEDLINE -DCOM- 20090707 -LR - 20090529 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 10 -IP - 4 -DP - 2009 Apr -TI - [Myocardial injury in carbon monoxide poisoning]. -PG - 227-33 -AB - Carbon monoxide (CO) intoxication is the most common cause of accidental - poisoning in developed countries and, although most published data relate to its - neurological manifestations, it often leads to cardiac damage. Myocardial hypoxia - due to the formation of carboxyhemoglobin is not enough to explain such damage - fully as a major role is played by the direct effect of CO on the heart as a - result of the reversible inhibition of mitochondrial respiration and oxidative - stress. Cardiac damage secondary to CO poisoning can be detected not only in - patients with known ischemic heart disease but also in subjects with undamaged - coronary arteries. Given the wide range of cardiovascular manifestations (the - entity of which is related to the severity of intoxication), useful information - can be obtained by carefully recording the patient's medical history, analyzing - electrocardiographic alterations, and determining the biochemical markers of - cardiac necrosis. Moreover, echocardiographic examination may highlight the - extent of the alterations in left ventricular function due to myocardial stunning - associated with CO intoxication and evaluate its evolution over time. Clinical - studies suggest that all patients admitted to hospital with moderate to severe CO - poisoning should routinely undergo ECG and serial evaluation of cardiac markers, - and that those with positive signs of myocardial cytonecrosis or preexisting - ischemic heart disease should also undergo echocardiography. A finding of - myocardial damage in patients with CO poisoning seems to indicate an unfavorable - long-term prognosis, although it needs further confirmation. -FAU - Rastelli, Gianni -AU - Rastelli G -AD - U.O. di Pronto Soccorso e Medicina d'Urgenza, Ospedale di Fidenza-AUSL di Parma, - Fidenza. grastelli@ausl.pr.it -FAU - Callegari, Sergio -AU - Callegari S -FAU - Locatelli, Carlo -AU - Locatelli C -FAU - Vezzani, Giuliano -AU - Vezzani G -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - Il danno miocardico indotto dall'intossicazione acuta da monossido di carbonio. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -SB - IM -MH - Carbon Monoxide Poisoning/*complications -MH - Cardiomyopathies/*chemically induced/diagnosis/physiopathology -MH - Humans -RF - 68 -EDAT- 2009/05/30 09:00 -MHDA- 2009/07/08 09:00 -CRDT- 2009/05/30 09:00 -PHST- 2009/05/30 09:00 [entrez] -PHST- 2009/05/30 09:00 [pubmed] -PHST- 2009/07/08 09:00 [medline] -PST - ppublish -SO - G Ital Cardiol (Rome). 2009 Apr;10(4):227-33. - -PMID- 17965966 -OWN - NLM -STAT- MEDLINE -DCOM- 20080915 -LR - 20240412 -IS - 1689-1392 (Electronic) -IS - 1425-8153 (Print) -IS - 1425-8153 (Linking) -VI - 13 -IP - 2 -DP - 2008 -TI - Natriuretic peptides in cardiovascular diseases. -PG - 155-81 -AB - The natriuretic peptide family comprises atrial natriuretic peptide (ANP), brain - natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis - natriuretic peptide (DNP), and urodilatin. The activities of natriuretic peptides - and endothelins are strictly associated with each other. ANP and BNP inhibit - endothelin-1 (ET-1) production. ET-1 stimulates natriuretic peptide synthesis. - All natriuretic peptides are synthesized from polypeptide precursors. Changes in - natriuretic peptides and endothelin release were observed in many cardiovascular - diseases: e.g. chronic heart failure, left ventricular dysfunction and coronary - artery disease. -FAU - Piechota, Mariusz -AU - Piechota M -AD - Department of Anaesthesiology and Intensive Care Unit, Boleslaw Szarecki - University Hospital No. 5 in Łódź, Medical University in Łódź, Łódź, Poland. -FAU - Banach, Maciej -AU - Banach M -FAU - Jacoń, Anna -AU - Jacoń A -FAU - Rysz, Jacek -AU - Rysz J -LA - eng -PT - Journal Article -PT - Review -DEP - 20080410 -PL - England -TA - Cell Mol Biol Lett -JT - Cellular & molecular biology letters -JID - 9607427 -RN - 0 (Endothelins) -RN - 0 (Natriuretic Peptides) -SB - IM -MH - Amino Acid Sequence -MH - Cardiovascular Diseases/genetics/*metabolism -MH - Endothelins/metabolism -MH - Humans -MH - Molecular Sequence Data -MH - Natriuretic Peptides/chemistry/*metabolism -PMC - PMC6275881 -EDAT- 2007/10/30 09:00 -MHDA- 2008/09/16 09:00 -PMCR- 2008/04/10 -CRDT- 2007/10/30 09:00 -PHST- 2007/01/18 00:00 [received] -PHST- 2007/05/08 00:00 [accepted] -PHST- 2007/10/30 09:00 [pubmed] -PHST- 2008/09/16 09:00 [medline] -PHST- 2007/10/30 09:00 [entrez] -PHST- 2008/04/10 00:00 [pmc-release] -AID - 46 [pii] -AID - 10.2478/s11658-007-0046-6 [doi] -PST - ppublish -SO - Cell Mol Biol Lett. 2008;13(2):155-81. doi: 10.2478/s11658-007-0046-6. Epub 2008 - Apr 10. - -PMID- 22890075 -OWN - NLM -STAT- MEDLINE -DCOM- 20130418 -LR - 20120914 -IS - 1876-4738 (Electronic) -IS - 0914-5087 (Linking) -VI - 60 -IP - 3 -DP - 2012 Sep -TI - Catheter intervention for adult patients with congenital heart disease. -PG - 151-9 -LID - S0914-5087(12)00126-8 [pii] -LID - 10.1016/j.jjcc.2012.06.014 [doi] -AB - Adult congenital heart disease is one of the most important clinical issues not - only for pediatric cardiologists but also adult cardiologists. After the - introduction of catheter intervention for atrial septal defect in the pediatric - population, therapeutic advantages of this less invasive procedure now focused on - even geriatric patients. The most valuable clinical benefit of this procedure is - the significant improvement in symptoms and daily activities, which result from - the closure of left to right shunt without thoracotomy or cardiopulmonary bypass - surgery. Although currently available therapeutic options for device closure for - congenital heart disease in Japan are limited to atrial septal defect, patent - ductus arteriosus, or some vascular abnormalities such as coronary arteriovenous - fistula, various new techniques or devices such as ventricular septal defect - device, pulmonary valve implantation, are going to be introduced in the near - future. To perform safely and achieve good procedure success, real time imaging - plays an important role in interventional procedures. Real time three-dimensional - transesophageal echocardiography can provide high quality imaging for anatomical - evaluation including defect size, surrounding rim morphology, and the - relationship between device and septal rim. In adult patients, optimal management - of comorbidities is an important issue, including cardiac function, arrhythmias, - pulmonary function, and renal function. In particular, atrial arrhythmias are key - issues for long-term outcome. Because the interventional procedures are not - complication-free techniques, the establishment of a surgical back-up system is - essential for achieving a safe procedure. Finally, the establishment of a team - approach including pediatric and adult cardiologists, cardiac surgeons, and - anesthesiologists is the most important factor for a good therapeutic outcome. - Their roles include pre-interventional hemodynamic evaluation, good imaging - technique for anatomical evaluation, management of comorbidities, and surgical - back up. -CI - Copyright © 2012 Japanese College of Cardiology. Published by Elsevier Ltd. All - rights reserved. -FAU - Akagi, Teiji -AU - Akagi T -AD - Cardiac Intensive Care Unit, Okayama University Hospital, Okayama, Japan. - t-akagi@cc.okayama-u.ac.jp -LA - eng -PT - Journal Article -PT - Review -DEP - 20120811 -PL - Netherlands -TA - J Cardiol -JT - Journal of cardiology -JID - 8804703 -SB - IM -MH - Adult -MH - *Cardiac Catheterization -MH - Ductus Arteriosus, Patent/therapy -MH - Heart Defects, Congenital/*therapy -MH - Heart Septal Defects, Atrial/surgery -MH - Humans -EDAT- 2012/08/15 06:00 -MHDA- 2013/04/20 06:00 -CRDT- 2012/08/15 06:00 -PHST- 2012/05/30 00:00 [received] -PHST- 2012/06/07 00:00 [accepted] -PHST- 2012/08/15 06:00 [entrez] -PHST- 2012/08/15 06:00 [pubmed] -PHST- 2013/04/20 06:00 [medline] -AID - S0914-5087(12)00126-8 [pii] -AID - 10.1016/j.jjcc.2012.06.014 [doi] -PST - ppublish -SO - J Cardiol. 2012 Sep;60(3):151-9. doi: 10.1016/j.jjcc.2012.06.014. Epub 2012 Aug - 11. - -PMID- 21180308 -OWN - NLM -STAT- MEDLINE -DCOM- 20110224 -LR - 20171116 -IS - 0019-4832 (Print) -IS - 0019-4832 (Linking) -VI - 62 -IP - 2 -DP - 2010 Mar-Apr -TI - Beta blockers in acute myocardial infarction. -PG - 148-53 -FAU - Jariwala, Pankaj V -AU - Jariwala PV -AD - Institut Cardiovasculaire Paris Sud, Paris, France. -FAU - Lathi, Pravir -AU - Lathi P -FAU - Ramesh, G -AU - Ramesh G -FAU - Saha, Deepak -AU - Saha D -FAU - Chandra, K Sarat -AU - Chandra KS -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - India -TA - Indian Heart J -JT - Indian heart journal -JID - 0374675 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Antihypertensive Agents) -RN - 9Y8NXQ24VQ (Propranolol) -SB - IM -MH - Acute Disease -MH - Administration, Oral -MH - Adrenergic beta-Antagonists/administration & dosage/adverse - effects/classification/pharmacology/*therapeutic use -MH - Angina Pectoris/drug therapy -MH - Angioplasty, Balloon, Coronary -MH - Anti-Arrhythmia Agents/administration & dosage/therapeutic use -MH - Antihypertensive Agents/administration & dosage/therapeutic use -MH - Arrhythmias, Cardiac/drug therapy -MH - Congresses as Topic -MH - Contraindications -MH - Diabetes Complications -MH - Humans -MH - Hypertension/drug therapy -MH - Myocardial Infarction/*drug therapy/therapy -MH - Practice Guidelines as Topic -MH - Propranolol/administration & dosage/therapeutic use -MH - Randomized Controlled Trials as Topic -MH - *Registries -MH - Time Factors -EDAT- 2010/12/25 06:00 -MHDA- 2011/02/25 06:00 -CRDT- 2010/12/25 06:00 -PHST- 2010/12/25 06:00 [entrez] -PHST- 2010/12/25 06:00 [pubmed] -PHST- 2011/02/25 06:00 [medline] -PST - ppublish -SO - Indian Heart J. 2010 Mar-Apr;62(2):148-53. - -PMID- 19112819 -OWN - NLM -STAT- MEDLINE -DCOM- 20090122 -LR - 20170306 -VI - 118 -IP - 10 -DP - 2008 Oct -TI - Chronic heart failure in the elderly: a current medical problem. -PG - 572-80 -AB - As a result of population ageing and improved medical care that contribute to - better life expectancy, heart failure occurs more and more commonly in the - elderly. In the USA approximately 80% of patients discharged from hospital with - newly diagnosed heart failure are over 65 years of age, whereas 50% are over 75. - The average 5-year mortality rate is about 50% in subjects with systolic - dysfunction and similar in those with preserved left ventricular systolic - function. Disorders of the cardiovascular system occurring in the elderly (e.g. - increased left ventricular mass, myocardial rigidity, atrial fibrillation, - decreased maximum oxygen uptake in cardiopulmonary exercise tests) result from - the physiological ageing; they may also be caused by a concomitant cardiac - failure syndrome. In the elderly, heart failure is often accompanied by - concomitant conditions that often make diagnosis and treatment of chronic heart - disease difficult. Non-specific clinical symptoms in the elderly as well as those - associated with age (e.g. easy fatigability, exertional dyspnea) make a correct - diagnosis difficult. The recognized biochemical marker of heart failure--brain - natriuretic peptide, N-terminal pro-brain natriuretic peptide--has a limited - diagnostic value in the elderly. Echocardiography plays a key role in the - diagnosis. Owing to altered metabolism, impairment of hepatic processes to - various degrees and decreased renal excretion of drugs, treatment requires - attention, individual choice of drugs and doses, as well as periodic modification - of both the doses and the intervals between them. Correct treatment improves - quality of life and prolongs it. The aim of the present work is to present the - differences in the pathophysiology, diagnostic evaluation and management of - chronic heart failure in the elderly, in light of the current views and - standards. -FAU - Nessler, Jadwiga -AU - Nessler J -AD - Department of Coronary Heart Disease, Institute of Cardiology, Jagiellonian - University School of Medicine, John Paul II Hospital, Kraków, Poland. - jnessler@interia.pl -FAU - Skrzypek, Agnieszka -AU - Skrzypek A -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Pol Arch Med Wewn -JT - Polskie Archiwum Medycyny Wewnetrznej -JID - 0401225 -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - 85637-73-6 (Atrial Natriuretic Factor) -SB - IM -MH - Age Factors -MH - Aged -MH - Aged, 80 and over -MH - Aging -MH - Atrial Natriuretic Factor/blood -MH - Electrocardiography/methods -MH - Geriatric Assessment/*methods -MH - Health Services for the Aged/*organization & administration -MH - Heart Failure/*diagnosis/*epidemiology/physiopathology/therapy -MH - Humans -MH - Middle Aged -MH - Natriuretic Peptide, Brain/blood -MH - Poland/epidemiology -MH - Prognosis -MH - Quality of Life -MH - Risk Factors -MH - Ultrasonography -MH - Ventricular Dysfunction, Left/diagnostic imaging -RF - 80 -EDAT- 2008/12/31 09:00 -MHDA- 2009/01/23 09:00 -CRDT- 2008/12/31 09:00 -PHST- 2008/12/31 09:00 [entrez] -PHST- 2008/12/31 09:00 [pubmed] -PHST- 2009/01/23 09:00 [medline] -PST - ppublish -SO - Pol Arch Med Wewn. 2008 Oct;118(10):572-80. - -PMID- 24037458 -OWN - NLM -STAT- MEDLINE -DCOM- 20150402 -LR - 20211021 -IS - 2193-6226 (Electronic) -IS - 2193-6218 (Linking) -VI - 108 -IP - 7 -DP - 2013 Oct -TI - [Patients in the intensive care unit with valvular diseases]. -PG - 555-60 -LID - 10.1007/s00063-012-0140-z [doi] -AB - Valvular dysfunction is as frequent as acute coronary syndromes in the - pathogenesis of acute decompensated heart failure. The prevalence of relevant - valvular dysfunction increases with age and reaches more than 10 % in patients - over 75 years old. Guidelines and studies on the treatment of these patients, - especially in an intensive care unit (ICU) setting are, however, scarce despite - excellent guidelines for treatment of valvular heart disease in the general - population. In the last decade a number of therapeutic alternatives became - available when standard inotrope and vasopressor therapy fails to stabilize - patients. These include balloon valvuloplasty in patients with severe aortic - valve stenosis and assist devices, extracorporeal membrane oxygenation (ECMO) as - well as mitral clipping. These therapeutic alternatives are to be considered as - bridge to operation procedures in cases of shock due to valvular dysfunction, as - hemodynamic stabilization and stabilization of organ function are essential to - allow valve repair/replacement which is still considered to be the gold standard - in this situation but is not always possible in the acute setting. -FAU - Geppert, A -AU - Geppert A -AD - 3. Medizinische Abteilung mit Kardiologie, Wilhelminenspital der Stadt Wien, - Montlearstr. 37, 1160, Wien, Österreich, alexander.geppert@wienkav.at. -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Patienten mit Klappenvitium auf der Intensivstation. -DEP - 20130915 -PL - Germany -TA - Med Klin Intensivmed Notfmed -JT - Medizinische Klinik, Intensivmedizin und Notfallmedizin -JID - 101575086 -SB - IM -MH - Balloon Valvuloplasty -MH - Echocardiography -MH - Extracorporeal Membrane Oxygenation -MH - Guideline Adherence -MH - Heart Failure/diagnosis/etiology/therapy -MH - Heart Valve Diseases/diagnosis/*therapy -MH - Humans -MH - *Intensive Care Units -MH - Mitral Valve/surgery -MH - Shock, Cardiogenic/diagnosis/etiology/therapy -EDAT- 2013/09/17 06:00 -MHDA- 2015/04/04 06:00 -CRDT- 2013/09/17 06:00 -PHST- 2013/07/02 00:00 [received] -PHST- 2013/07/30 00:00 [accepted] -PHST- 2013/07/15 00:00 [revised] -PHST- 2013/09/17 06:00 [entrez] -PHST- 2013/09/17 06:00 [pubmed] -PHST- 2015/04/04 06:00 [medline] -AID - 10.1007/s00063-012-0140-z [doi] -PST - ppublish -SO - Med Klin Intensivmed Notfmed. 2013 Oct;108(7):555-60. doi: - 10.1007/s00063-012-0140-z. Epub 2013 Sep 15. - -PMID- 23017720 -OWN - NLM -STAT- MEDLINE -DCOM- 20130219 -LR - 20120928 -IS - 0083-6729 (Print) -IS - 0083-6729 (Linking) -VI - 90 -DP - 2012 -TI - Adiponectin in the heart and vascular system. -PG - 289-319 -LID - B978-0-12-398313-8.00011-7 [pii] -LID - 10.1016/B978-0-12-398313-8.00011-7 [doi] -AB - Adipose tissue is not only a storage depot for energy, but also an active - endocrine tissue. Adipokines, hormones and cytokines secreted from adipocytes, - relay information about energy stores to peripheral tissues throughout the body. - Most adipokines are produced in direct proportion to fat mass, and many have - proinflammatory or otherwise adverse effects on the cardiovascular system. The - notable exception is the cardioprotective adipokine adiponectin, which is - secreted in inverse proportion to fat mass. Circulating adiponectin levels are - highest in lean individuals and inversely correlate with fat mass. Low levels of - serum adiponectin are now appreciated as a risk factor in a variety of - cardiovascular diseases including coronary artery disease and restenosis, type 2 - diabetes mellitus, and hypertension. In this chapter, we provide an introduction - to adiponectin and review the extensive evidence in humans and in mouse and in - vitro models for adiponectin's cardioprotective effects. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Ding, Min -AU - Ding M -AD - Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA. -FAU - Rzucidlo, Eva M -AU - Rzucidlo EM -FAU - Davey, Jennifer C -AU - Davey JC -FAU - Xie, Yi -AU - Xie Y -FAU - Liu, Renjing -AU - Liu R -FAU - Jin, Yu -AU - Jin Y -FAU - Stavola, Lindsey -AU - Stavola L -FAU - Martin, Kathleen A -AU - Martin KA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Vitam Horm -JT - Vitamins and hormones -JID - 0413601 -RN - 0 (Adiponectin) -RN - 0 (Receptors, Adiponectin) -SB - IM -MH - Adiponectin/biosynthesis/genetics/*physiology -MH - Adipose Tissue/pathology -MH - Adiposity -MH - Animals -MH - *Cardiovascular Diseases/pathology -MH - *Cardiovascular System -MH - Female -MH - Heart Transplantation -MH - Humans -MH - Male -MH - Myocardium/pathology -MH - Polymorphism, Single Nucleotide -MH - Receptors, Adiponectin/physiology -MH - Sex Factors -MH - Signal Transduction -EDAT- 2012/09/29 06:00 -MHDA- 2013/02/21 06:00 -CRDT- 2012/09/29 06:00 -PHST- 2012/09/29 06:00 [entrez] -PHST- 2012/09/29 06:00 [pubmed] -PHST- 2013/02/21 06:00 [medline] -AID - B978-0-12-398313-8.00011-7 [pii] -AID - 10.1016/B978-0-12-398313-8.00011-7 [doi] -PST - ppublish -SO - Vitam Horm. 2012;90:289-319. doi: 10.1016/B978-0-12-398313-8.00011-7. - -PMID- 18365500 -OWN - NLM -STAT- MEDLINE -DCOM- 20080428 -LR - 20220310 -IS - 1330-0164 (Print) -IS - 1330-0164 (Linking) -VI - 62 -IP - 1 -DP - 2008 Feb -TI - [Natriuretic peptides in clinical practice]. -PG - 53-6 -AB - The natriuretic peptide (NP) system is primarily an endocrine system that - maintains fluid and pressure homeostasis in healthy humans. The cardiac NP, ANP - (atrial natriuretic peptide) and BNP (brain natriuretic peptide) are secreted by - the heart in proportion to cardiac transmural pressures. The relationship between - plasma levels of these peptides and "cardiac load" has led to their use as - biomarkers of cardiac health with diagnostic and prognostic applications in a - variety of disorders affecting the cardiovascular system. Elevated NP levels may - serve as an early warning sign to help identify patients at a high risk of - cardiac events. BNP and its N-terminal fragment (NT-BNP) are especially sensitive - indicators for cardiac dysfunction and remodeling (correlate with severity) and - play a role in the detection of coronary artery disease. The favorable biological - properties of NP have also led to their use as therapeutic agents. Recombinant - human ANP (carperitide) and BNP (nesiritide) are useful in the management od - acutely decompensated heart failure. -FAU - Urek, Roman -AU - Urek R -AD - University Department of Cardiovascular Diseases, School of Medicine, University - of Zagreb, Sveti Duh General Hospital, Zagreb, Croatia. -FAU - Cubrilo-Turek, Mirjana -AU - Cubrilo-Turek M -LA - hrv -PT - English Abstract -PT - Journal Article -PT - Review -TT - Natriuretski peptidi u klinickoj praksi. -PL - Croatia -TA - Acta Med Croatica -JT - Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti -JID - 9208249 -RN - 0 (Biomarkers) -RN - 0 (Natriuretic Peptides) -SB - IM -MH - Biomarkers/blood -MH - Cardiovascular Diseases/*diagnosis -MH - Humans -MH - Natriuretic Peptides/*blood/physiology -RF - 34 -EDAT- 2008/03/28 09:00 -MHDA- 2008/04/29 09:00 -CRDT- 2008/03/28 09:00 -PHST- 2008/03/28 09:00 [pubmed] -PHST- 2008/04/29 09:00 [medline] -PHST- 2008/03/28 09:00 [entrez] -PST - ppublish -SO - Acta Med Croatica. 2008 Feb;62(1):53-6. - -PMID- 17485594 -OWN - NLM -STAT- MEDLINE -DCOM- 20070531 -LR - 20071115 -IS - 1524-4539 (Electronic) -IS - 0009-7322 (Linking) -VI - 115 -IP - 18 -DP - 2007 May 8 -TI - Mechanisms of sudden cardiac death in myocardial infarction survivors: insights - from the randomized trials of implantable cardioverter-defibrillators. -PG - 2451-7 -FAU - Bunch, T Jared -AU - Bunch TJ -AD - Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN - 55905, USA. -FAU - Hohnloser, Stefan H -AU - Hohnloser SH -FAU - Gersh, Bernard J -AU - Gersh BJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Circulation -JT - Circulation -JID - 0147763 -SB - IM -MH - Coronary Artery Bypass -MH - Death, Sudden, Cardiac/*etiology -MH - Defibrillators, Implantable/*statistics & numerical data -MH - Disease Progression -MH - Follow-Up Studies -MH - Heart Failure/mortality -MH - Humans -MH - Multicenter Studies as Topic/statistics & numerical data -MH - Myocardial Infarction/*epidemiology/surgery -MH - Myocardial Ischemia/complications -MH - Randomized Controlled Trials as Topic/statistics & numerical data -MH - Recurrence -MH - Risk Assessment -MH - Risk Factors -MH - Stroke Volume -MH - Survivors -MH - Time Factors -MH - Ventricular Dysfunction, Left/complications -MH - Ventricular Fibrillation/etiology/mortality -MH - Ventricular Remodeling -RF - 61 -EDAT- 2007/05/09 09:00 -MHDA- 2007/06/01 09:00 -CRDT- 2007/05/09 09:00 -PHST- 2007/05/09 09:00 [pubmed] -PHST- 2007/06/01 09:00 [medline] -PHST- 2007/05/09 09:00 [entrez] -AID - 115/18/2451 [pii] -AID - 10.1161/CIRCULATIONAHA.106.683235 [doi] -PST - ppublish -SO - Circulation. 2007 May 8;115(18):2451-7. doi: 10.1161/CIRCULATIONAHA.106.683235. - -PMID- 23876528 -OWN - NLM -STAT- MEDLINE -DCOM- 20140428 -LR - 20220422 -IS - 1433-2981 (Electronic) -IS - 0936-6555 (Linking) -VI - 25 -IP - 10 -DP - 2013 Oct -TI - Understanding radiation-induced cardiovascular damage and strategies for - intervention. -PG - 617-24 -LID - S0936-6555(13)00265-3 [pii] -LID - 10.1016/j.clon.2013.06.012 [doi] -AB - There is a clear association between therapeutic doses of thoracic irradiation - and an increased risk of cardiovascular disease (CVD) in cancer survivors, - although these effects may take decades to become symptomatic. Long-term - survivors of Hodgkin's lymphoma and childhood cancers have two-fold to more than - seven-fold increased risks for late cardiac deaths after total tumour doses of - 30-40 Gy, given in 2 Gy fractions, where large volumes of heart were included in - the field. Increased cardiac mortality is also seen in women irradiated for - breast cancer. Breast doses are generally 40-50 Gy in 2 Gy fractions, but only a - small part of the heart is included in the treatment fields and mean heart doses - rarely exceeded 10-15 Gy, even with older techniques. The relative risks of - cardiac mortality (1.1-1.4) are consequently lower than for Hodgkin's lymphoma - survivors. Some epidemiological studies show increased risks of cardiac death - after accidental or environmental total body exposures to much lower radiation - doses. The mechanisms whereby these cardiac effects occur are not fully - understood and different mechanisms are probably involved after high therapeutic - doses to the heart, or part of the heart, than after low total body exposures. - These various mechanisms probably result in different cardiac pathologies, e.g. - coronary artery atherosclerosis leading to myocardial infarct, versus - microvascular damage and fibrosis leading to congestive heart failure. - Experimental studies can help to unravel some of these mechanisms and may - identify suitable strategies for managing or inhibiting CVD. In this overview, - the main epidemiological and clinical evidence for radiation-induced CVD is - summarised. Experimental data shedding light on some of the underlying - pathologies and possible targets for intervention are also discussed. -CI - © 2013 Published by Elsevier Ltd on behalf of The Royal College of Radiologists. -FAU - Stewart, F A -AU - Stewart FA -AD - Division of Biological Stress Response, The Netherlands Cancer Institute, - Amsterdam, The Netherlands. f.stewart@nki.nl -FAU - Seemann, I -AU - Seemann I -FAU - Hoving, S -AU - Hoving S -FAU - Russell, N S -AU - Russell NS -LA - eng -PT - Journal Article -PT - Review -DEP - 20130720 -PL - England -TA - Clin Oncol (R Coll Radiol) -JT - Clinical oncology (Royal College of Radiologists (Great Britain)) -JID - 9002902 -SB - IM -MH - Cardiovascular Diseases/*etiology/pathology -MH - Humans -MH - Neoplasms/*radiotherapy -MH - Radiation Injuries/*etiology/pathology -MH - Thorax/radiation effects -OTO - NOTNLM -OT - Atherosclerosis -OT - cardiovascular disease -OT - microvascular damage -OT - radiation -EDAT- 2013/07/24 06:00 -MHDA- 2014/04/29 06:00 -CRDT- 2013/07/24 06:00 -PHST- 2013/03/06 00:00 [received] -PHST- 2013/04/26 00:00 [revised] -PHST- 2013/06/30 00:00 [accepted] -PHST- 2013/07/24 06:00 [entrez] -PHST- 2013/07/24 06:00 [pubmed] -PHST- 2014/04/29 06:00 [medline] -AID - S0936-6555(13)00265-3 [pii] -AID - 10.1016/j.clon.2013.06.012 [doi] -PST - ppublish -SO - Clin Oncol (R Coll Radiol). 2013 Oct;25(10):617-24. doi: - 10.1016/j.clon.2013.06.012. Epub 2013 Jul 20. - -PMID- 17378995 -OWN - NLM -STAT- MEDLINE -DCOM- 20070503 -LR - 20221207 -IS - 0002-9149 (Print) -IS - 0002-9149 (Linking) -VI - 99 -IP - 6B -DP - 2007 Mar 26 -TI - From hypertension to heart failure: role of nitric oxide-mediated endothelial - dysfunction and emerging insights from myocardial contrast echocardiography. -PG - 7D-14D -AB - There is growing evidence that nitric oxide (NO)-mediated endothelial dysfunction - occurs in hypertension and may represent the earliest stage of target organ - damage, which ultimately leads to hypertensive heart disease and heart failure - (HF). An understanding of how impaired myocardial microvascular function and flow - reserve relate to early remodeling during the transition to HF in patients with - hypertension may lead to new therapeutic insights. The hypertrophied heart, which - is a feature of the adverse structural remodeling in hypertensive heart disease, - may be accompanied by impaired coronary flow reserve (CFR). Reduced CFR could - potentially cause subendocardial ischemia during conditions of high metabolic - demand, such as uncontrolled hypertension and tachycardia. Such vulnerability of - the subendocardium to abnormal perfusion or ischemia may accelerate the - progression from compensated hypertrophy to HF. In this review, we discuss - preliminary evidence that altered NO balance may contribute to cardiac - hypertrophy-mediated myocardial ischemia. We also describe early results with - myocardial contrast echocardiography in the postulated transition from - compensated hypertrophy to cardiac failure. These data support further evaluation - of NO mediators as potential targets for novel therapies in hypertensive heart - disease. -FAU - Lapu-Bula, Rigobert -AU - Lapu-Bula R -AD - Division of Cardiology and the Clinical Research Center, Morehouse School of - Medicine, Atlanta, Georgia 30310, USA. -FAU - Ofili, Elizabeth -AU - Ofili E -LA - eng -GR - 1U54RR22814-01/RR/NCRR NIH HHS/United States -GR - 5P20RR11104/RR/NCRR NIH HHS/United States -GR - 5U54 RR14758/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -DEP - 20070129 -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -RN - 0 (Nitric Oxide Donors) -RN - 11062-77-4 (Superoxides) -RN - 31C4KY9ESH (Nitric Oxide) -RN - IA7306519N (Isosorbide Dinitrate) -SB - IM -MH - Black or African American -MH - Aged -MH - Drug Therapy, Combination -MH - Echocardiography -MH - Female -MH - Heart Failure/drug therapy/*etiology -MH - Humans -MH - Hypertension/*complications/drug therapy -MH - Isosorbide Dinitrate/*therapeutic use -MH - Male -MH - Nitric Oxide/*physiology -MH - Nitric Oxide Donors/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Superoxides/metabolism -MH - Ventricular Remodeling/*physiology -RF - 51 -EDAT- 2007/03/24 09:00 -MHDA- 2007/05/04 09:00 -CRDT- 2007/03/24 09:00 -PHST- 2007/03/24 09:00 [pubmed] -PHST- 2007/05/04 09:00 [medline] -PHST- 2007/03/24 09:00 [entrez] -AID - S0002-9149(06)02478-7 [pii] -AID - 10.1016/j.amjcard.2006.12.014 [doi] -PST - ppublish -SO - Am J Cardiol. 2007 Mar 26;99(6B):7D-14D. doi: 10.1016/j.amjcard.2006.12.014. Epub - 2007 Jan 29. - -PMID- 17426749 -OWN - NLM -STAT- MEDLINE -DCOM- 20070501 -LR - 20161020 -IS - 0831-2796 (Print) -IS - 0831-2796 (Linking) -VI - 49 -IP - 11 -DP - 2006 Nov -TI - Genetic susceptibility to heart disease in Canada: lessons from patients with - familial hypercholesterolemia. -PG - 1343-50 -AB - Much of the recent progress in treating patients with heart disease due to - narrowed coronary arteries has resulted from studying disease evolution in - patients with rare monogenic forms of disease. For instance, autosomal dominant - familial hypercholesterolemia (FH, MIM (Mendelian Inheritance in Man) 143890) - typically results from heterozygous mutations in LDLR encoding the low-density - lipoprotein (LDL) receptor. Deficient LDLR activity results in elevated - circulating LDL cholesterol, which accumulates within blood vessel walls, forming - arterial plaques that can grow and eventually occlude the arterial lumen. - Heterozygous LDLR mutations are usually detected using exon-by-exon sequence - analysis (EBESA) of genomic DNA, a technology that has identified approximately - 50 mutations in heterozygous FH (HeFH) subjects in Ontario. However, - approximately 35% of Ontario HeFH patients had no EBESA-identified LDLR mutation. - The diagnostic gap relates both to the genetic heterogeneity of FH and also to - inadequate sensitivity of EBESA to detect certain mutation types, such as large - deletions or insertions in LDLR. By means of a dedicated method to detect copy - number variations (CNVs), additional heterozygous mutations in LDLR ranging from - approximately 500 to >15 000 bases were uncovered, accounting for most of the - remainder of Ontario HeFH patients. The appreciation of the key role of genomic - CNVs in disease coincides with recent genome-wide mapping studies demonstrating - that CNVs are common in apparently healthy people. CNVs thus represent a new - level of genomic variation that is both an important mechanism of monogenic - disease and a contributor to genomic variation in the general population; as - well, it may have implications for evolution, biology, and possibly - susceptibility to common complex diseases. -FAU - Hegele, Robert A -AU - Hegele RA -AD - Blackburn Cardiovascular Genetics Laboratory, Robarts Research Institute, - Schulich School of Medicine and Dentistry, University of Western Ontario, 406-100 - Perth Drive, London, ON N6A 5K8, Canada. hegele@robarts.ca -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Canada -TA - Genome -JT - Genome -JID - 8704544 -RN - 0 (Receptors, LDL) -SB - IM -MH - Canada -MH - *Genetic Predisposition to Disease -MH - *Genetic Variation -MH - Humans -MH - Hyperlipoproteinemia Type II/etiology/*genetics -MH - *Mutation -MH - Receptors, LDL/*genetics -RF - 20 -EDAT- 2007/04/12 09:00 -MHDA- 2007/05/02 09:00 -CRDT- 2007/04/12 09:00 -PHST- 2007/04/12 09:00 [pubmed] -PHST- 2007/05/02 09:00 [medline] -PHST- 2007/04/12 09:00 [entrez] -AID - g06-147 [pii] -AID - 10.1139/g06-147 [doi] -PST - ppublish -SO - Genome. 2006 Nov;49(11):1343-50. doi: 10.1139/g06-147. - -PMID- 21417012 -OWN - NLM -STAT- MEDLINE -DCOM- 20121001 -LR - 20110321 -IS - 0559-7765 (Print) -IS - 0559-7765 (Linking) -VI - 41 -IP - 1 -DP - 2010 Feb -TI - [Diabetic cardiomyopathy]. -PG - 31-6 -AB - Diabetic cardiomyopathy is characterized by myocardial hypertrophy and fibrosis - independent of hypertension, coronary artery disease or other idiopathic heart - diseases. The underlying mechanisms of diabetic cardiomyopathy are still elusive. - Previous studies have highlighted the importance of metabolic disturbances - (dysfunction of glucose transporters, increased free fatty acids, abnormal - changes in calcium homeostasis, disordered copper metabolism, insulin - resistance), myocardial fibrosis (association with hyperglycemia, myocyte - apoptosis, increases in angiotensin II , IGF-1, and pro-inflammatory cytokines, - changes in matrix metalloproteinases activity etc.), cardiac autonomic - neuropathy, and stem cell in the evolution of diabetic cardiomyopathy. The - current overview will focus on the recent advance of pathogenesis of diabetic - cardiomyopathy and may help to define the pathology of diabetes related heart - diseases. -FAU - Huang, Ya-Qian -AU - Huang YQ -AD - Department of Physiology and Pathophysiology, Peking University Health Science - Center, Beijing 100191, China. -FAU - Wang, Xian -AU - Wang X -FAU - Kong, Wei -AU - Kong W -LA - chi -PT - English Abstract -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - China -TA - Sheng Li Ke Xue Jin Zhan -JT - Sheng li ke xue jin zhan [Progress in physiology] -JID - 20730140R -SB - IM -MH - Animals -MH - Cardiomyopathy, Hypertrophic/pathology/physiopathology -MH - Diabetic Cardiomyopathies/*etiology/pathology/*physiopathology -MH - Fibrosis -MH - Humans -MH - Myocardium/pathology -EDAT- 2011/03/23 06:00 -MHDA- 2012/10/02 06:00 -CRDT- 2011/03/23 06:00 -PHST- 2011/03/23 06:00 [entrez] -PHST- 2011/03/23 06:00 [pubmed] -PHST- 2012/10/02 06:00 [medline] -PST - ppublish -SO - Sheng Li Ke Xue Jin Zhan. 2010 Feb;41(1):31-6. - -PMID- 18453787 -OWN - NLM -STAT- MEDLINE -DCOM- 20080729 -LR - 20080505 -IS - 1016-5169 (Print) -IS - 1016-5169 (Linking) -VI - 36 -IP - 1 -DP - 2008 Jan -TI - [Obstructive sleep apnea syndrome and cardiac arrhythmias]. -PG - 44-50 -AB - Obstructive sleep apnea syndrome (OSAS) refers to recurring episodes of upper - respiratory track obstruction and frequent decreases in arterial oxygen - saturation due to repetitive occlusions of the posterior pharynx during sleep. - Its prevalence in adult population is 4% in men and 2% in women. The most - important causes of morbidity and mortality in affected patients are traffic - accidents and cardiovascular complications including systemic arterial - hypertension, coronary artery disease, congestive heart failure, and cardiac - arrhythmias. The initial phases of apnea are associated with a transient increase - in the parasympathetic activity resulting in bradyarrhythmias, followed by - tachycardias due to increased sympathetic activity and arousal after the end of - apnea episodes. The most frequent arrhythmia in OSAS is cyclic variation of heart - rate. Most of the arrhythmias seen in OSAS are secondary to OSAS and disappear - with OSAS treatment, without any electrophysiological conduction system - abnormalities. -FAU - Bayram, Nihal Akar -AU - Bayram NA -AD - Atatürk Eğitim ve Araştirma Hastanesi Kardiyoloji Kliniği, Ankara. - drnihkar@yahoo.co.uk -FAU - Diker, Erdem -AU - Diker E -LA - tur -PT - English Abstract -PT - Journal Article -PT - Review -TT - Obstrüktif uyku apnesi sendromu ve kardiyak aritmi. -PL - Turkey -TA - Turk Kardiyol Dern Ars -JT - Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir -JID - 9426239 -SB - IM -MH - Arrhythmias, Cardiac/etiology/*physiopathology -MH - Electrocardiography -MH - Humans -MH - Sleep Apnea, Obstructive/complications/*physiopathology -RF - 39 -EDAT- 2008/05/06 09:00 -MHDA- 2008/07/30 09:00 -CRDT- 2008/05/06 09:00 -PHST- 2008/05/06 09:00 [pubmed] -PHST- 2008/07/30 09:00 [medline] -PHST- 2008/05/06 09:00 [entrez] -PST - ppublish -SO - Turk Kardiyol Dern Ars. 2008 Jan;36(1):44-50. - -PMID- 20553581 -OWN - NLM -STAT- MEDLINE -DCOM- 20100923 -LR - 20250626 -IS - 1741-7015 (Electronic) -IS - 1741-7015 (Linking) -VI - 8 -DP - 2010 Jun 16 -TI - Triple antiplatelet therapy for preventing vascular events: a systematic review - and meta-analysis. -PG - 36 -LID - 10.1186/1741-7015-8-36 [doi] -AB - BACKGROUND: Dual antiplatelet therapy is usually superior to mono therapy in - preventing recurrent vascular events (VEs). This systematic review assesses the - safety and efficacy of triple antiplatelet therapy in comparison with dual - therapy in reducing recurrent vascular events. METHODS: Completed randomized - controlled trials investigating the effect of triple versus dual antiplatelet - therapy in patients with ischaemic heart disease (IHD), cerebrovascular disease - or peripheral vascular disease were identified using electronic bibliographic - searches. Data were extracted on composite VEs, myocardial infarction (MI), - stroke, death and bleeding and analysed with Cochrane Review Manager software. - Odds ratios (OR) and 95% confidence intervals (CI) were calculated using random - effects models. RESULTS: Twenty-five completed randomized trials (17,383 patients - with IHD) were included which involving the use of intravenous (iv) GP IIb/IIIa - inhibitors (abciximab, eptifibatide, tirofiban), aspirin, clopidogrel and/or - cilostazol. In comparison with aspirin-based therapy, triple therapy using an - intravenous GP IIb/IIIa inhibitor significantly reduced composite VEs and MI in - patients with non-ST elevation acute coronary syndromes (NSTE-ACS) (VE: OR 0.69, - 95% CI 0.55-0.86; MI: OR 0.70, 95% CI 0.56-0.88) and ST elevation myocardial - infarction (STEMI) (VE: OR 0.39, 95% CI 0.30-0.51; MI: OR 0.26, 95% CI - 0.17-0.38). A significant reduction in death was also noted in STEMI patients - treated with GP IIb/IIIa based triple therapy (OR 0.69, 95% CI 0.49-0.99). - Increased minor bleeding was noted in STEMI and elective percutaneous coronary - intervention (PCI) patients treated with GP IIb/IIIa based triple therapy. Stroke - events were too infrequent for us to be able to identify meaningful trends and no - data were available for patients recruited into trials on the basis of stroke or - peripheral vascular disease. CONCLUSIONS: Triple antiplatelet therapy based on iv - GPIIb/IIIa inhibitors was more effective than aspirin-based dual therapy in - reducing VEs in patients with acute coronary syndromes (STEMI and NSTEMI). Minor - bleeding was increased among STEMI and elective PCI patients treated with a GP - IIb/IIIa based triple therapy. In patients undergoing elective PCI, triple - therapy had no beneficial effect and was associated with an 80% increase in - transfusions and an eightfold increase in thrombocytopenia. Insufficient data - exist for patients with prior ischaemic stroke and peripheral vascular disease - and further research is needed in these groups of patients. -FAU - Geeganage, Chamila -AU - Geeganage C -AD - Stroke Trials Unit, Institute of Neuroscience, Division of Stroke, University of - Nottingham, City Hospital Campus, Nottingham, UK. -FAU - Wilcox, Robert -AU - Wilcox R -FAU - Bath, Philip M W -AU - Bath PM -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20100616 -PL - England -TA - BMC Med -JT - BMC medicine -JID - 101190723 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Brain Ischemia/complications/drug therapy -MH - Drug Therapy, Combination/methods -MH - Humans -MH - Myocardial Ischemia/complications/drug therapy -MH - Platelet Aggregation Inhibitors/*adverse effects/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Secondary Prevention -MH - Treatment Outcome -MH - Vascular Diseases/*prevention & control -PMC - PMC2893089 -EDAT- 2010/06/18 06:00 -MHDA- 2010/09/24 06:00 -PMCR- 2010/06/16 -CRDT- 2010/06/18 06:00 -PHST- 2009/11/16 00:00 [received] -PHST- 2010/06/16 00:00 [accepted] -PHST- 2010/06/18 06:00 [entrez] -PHST- 2010/06/18 06:00 [pubmed] -PHST- 2010/09/24 06:00 [medline] -PHST- 2010/06/16 00:00 [pmc-release] -AID - 1741-7015-8-36 [pii] -AID - 10.1186/1741-7015-8-36 [doi] -PST - epublish -SO - BMC Med. 2010 Jun 16;8:36. doi: 10.1186/1741-7015-8-36. - -PMID- 16910416 -OWN - NLM -STAT- MEDLINE -DCOM- 20061010 -LR - 20161124 -IS - 0024-3477 (Print) -IS - 0024-3477 (Linking) -VI - 128 -IP - 5-6 -DP - 2006 May-Jun -TI - [Doppler echocardiographic assessment of diastolic function of left ventricle]. -PG - 153-61 -AB - Approximately half of the patients with overt congestive heart failure (CHF) have - diastolic dysfunction without reduced ejection fraction (LVEF>50%). Diastolic - dysfunction is an abnormality in left ventricular myocardial relaxation and/or - compliance that alters the ease with which blood is accepted into the left - ventricle during diastole. Elevated pressures in the left atrium are - compensatory, ensuring adequate filling. All patients with systolic dysfunction - have concomitant diastolic dysfunction. Indeed, in patients with CHF and reduced - systolic function the level of diastolic dysfunction influences the severity of - symptoms. It is now clear that hypertension, coronary artery disease and other - diseases and conditions commonly produce diastolic dysfunction in the absence of - significant systolic dysfunction. Accurate noninvasive Doppler-echocardiographic - assessment of the presence and severity of diastolic impairment is crucial to the - broad application and understanding of this common condition. This review - discusses the clinical impact of classic and recent echocardiographic - contributions to the field of diastology. -FAU - Bozić, Ivo -AU - Bozić I -AD - Klinika za unutrasnje bolesti. ibozic@kbsplit.hr -FAU - Polić, Stojan -AU - Polić S -FAU - Rakić, Drago -AU - Rakić D -FAU - Carević, Vedran -AU - Carević V -LA - hrv -PT - Journal Article -PT - Review -TT - Doplerehokardiografska procjena dijastolicke funkcije lijeve klijetke. -PL - Croatia -TA - Lijec Vjesn -JT - Lijecnicki vjesnik -JID - 0074253 -SB - IM -MH - Diastole -MH - *Echocardiography, Doppler -MH - Heart Failure/complications -MH - Humans -MH - Ventricular Dysfunction, Left/*diagnostic imaging/physiopathology -RF - 28 -EDAT- 2006/08/17 09:00 -MHDA- 2006/10/13 09:00 -CRDT- 2006/08/17 09:00 -PHST- 2006/08/17 09:00 [pubmed] -PHST- 2006/10/13 09:00 [medline] -PHST- 2006/08/17 09:00 [entrez] -PST - ppublish -SO - Lijec Vjesn. 2006 May-Jun;128(5-6):153-61. - -PMID- 21440695 -OWN - NLM -STAT- MEDLINE -DCOM- 20110922 -LR - 20161125 -IS - 1558-4623 (Electronic) -IS - 0001-2998 (Linking) -VI - 41 -IP - 3 -DP - 2011 May -TI - Cardiac cameras. -PG - 182-201 -LID - 10.1053/j.semnuclmed.2010.12.007 [doi] -AB - Cardiac imaging with radiotracers plays an important role in patient evaluation, - and the development of suitable imaging instruments has been crucial. While - initially performed with the rectilinear scanner that slowly transmitted, in a - row-by-row fashion, cardiac count distributions onto various printing media, the - Anger scintillation camera allowed electronic determination of tracer energies - and of the distribution of radioactive counts in 2D space. Increased - sophistication of cardiac cameras and development of powerful computers to - analyze, display, and quantify data has been essential to making radionuclide - cardiac imaging a key component of the cardiac work-up. Newer processing - algorithms and solid state cameras, fundamentally different from the Anger - camera, show promise to provide higher counting efficiency and resolution, - leading to better image quality, more patient comfort and potentially lower - radiation exposure. While the focus has been on myocardial perfusion imaging with - single-photon emission computed tomography, increased use of positron emission - tomography is broadening the field to include molecular imaging of the myocardium - and of the coronary vasculature. Further advances may require integrating cardiac - nuclear cameras with other imaging devices, ie, hybrid imaging cameras. The goal - is to image the heart and its physiological processes as accurately as possible, - to prevent and cure disease processes. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Travin, Mark I -AU - Travin MI -AD - Department of Nuclear Medicine, Montefiore Medical Center, Albert Einstein - College of Medicine, Bronx, NY 10467-2490, USA. mtravin@montefiore.org -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Semin Nucl Med -JT - Seminars in nuclear medicine -JID - 1264464 -SB - IM -MH - Animals -MH - Diagnostic Imaging/*instrumentation -MH - Gamma Cameras -MH - *Heart/diagnostic imaging -MH - Humans -MH - Image Processing, Computer-Assisted -MH - Radionuclide Imaging -MH - Software -MH - Systems Integration -EDAT- 2011/03/29 06:00 -MHDA- 2011/09/23 06:00 -CRDT- 2011/03/29 06:00 -PHST- 2011/03/29 06:00 [entrez] -PHST- 2011/03/29 06:00 [pubmed] -PHST- 2011/09/23 06:00 [medline] -AID - S0001-2998(10)00164-9 [pii] -AID - 10.1053/j.semnuclmed.2010.12.007 [doi] -PST - ppublish -SO - Semin Nucl Med. 2011 May;41(3):182-201. doi: 10.1053/j.semnuclmed.2010.12.007. - -PMID- 24009586 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20131106 -LR - 20231106 -IS - 1664-042X (Print) -IS - 1664-042X (Electronic) -IS - 1664-042X (Linking) -VI - 4 -DP - 2013 -TI - Hyperkalemic cardioplegia for adult and pediatric surgery: end of an era? -PG - 228 -LID - 10.3389/fphys.2013.00228 [doi] -LID - 228 -AB - Despite surgical proficiency and innovation driving low mortality rates in - cardiac surgery, the disease severity, comorbidity rate, and operative procedural - difficulty have increased. Today's cardiac surgery patient is older, has a - "sicker" heart and often presents with multiple comorbidities; a scenario that - was relatively rare 20 years ago. The global challenge has been to find new ways - to make surgery safer for the patient and more predictable for the surgeon. A - confounding factor that may influence clinical outcome is high K(+) cardioplegia. - For over 40 years, potassium depolarization has been linked to transmembrane - ionic imbalances, arrhythmias and conduction disturbances, vasoconstriction, - coronary spasm, contractile stunning, and low output syndrome. Other than - inducing rapid electrochemical arrest, high K(+) cardioplegia offers little or no - inherent protection to adult or pediatric patients. This review provides a brief - history of high K(+) cardioplegia, five areas of increasing concern with - prolonged membrane K(+) depolarization, and the basic science and clinical data - underpinning a new normokalemic, "polarizing" cardioplegia comprising adenosine - and lidocaine (AL) with magnesium (Mg(2+)) (ALM™). We argue that improved - cardioprotection, better outcomes, faster recoveries and lower healthcare costs - are achievable and, despite the early predictions from the stent industry and - cardiology, the "cath lab" may not be the place where the new wave of high-risk - morbid patients are best served. -FAU - Dobson, Geoffrey P -AU - Dobson GP -AD - Department of Physiology and Pharmacology, Heart and Trauma Research Laboratory, - James Cook University Townsville, QLD, Australia. -FAU - Faggian, Giuseppe -AU - Faggian G -FAU - Onorati, Francesco -AU - Onorati F -FAU - Vinten-Johansen, Jakob -AU - Vinten-Johansen J -LA - eng -PT - Journal Article -PT - Review -DEP - 20130828 -PL - Switzerland -TA - Front Physiol -JT - Frontiers in physiology -JID - 101549006 -PMC - PMC3755226 -OTO - NOTNLM -OT - cardiac surgery -OT - cardioplegia -OT - endothelium -OT - heart -OT - history -OT - hyperkalemia -OT - ischemia -OT - potassium -EDAT- 2013/09/07 06:00 -MHDA- 2013/09/07 06:01 -PMCR- 2013/08/28 -CRDT- 2013/09/07 06:00 -PHST- 2013/04/15 00:00 [received] -PHST- 2013/08/05 00:00 [accepted] -PHST- 2013/09/07 06:00 [entrez] -PHST- 2013/09/07 06:00 [pubmed] -PHST- 2013/09/07 06:01 [medline] -PHST- 2013/08/28 00:00 [pmc-release] -AID - 10.3389/fphys.2013.00228 [doi] -PST - epublish -SO - Front Physiol. 2013 Aug 28;4:228. doi: 10.3389/fphys.2013.00228. eCollection - 2013. - -PMID- 17336664 -OWN - NLM -STAT- MEDLINE -DCOM- 20070508 -LR - 20250623 -IS - 0163-8343 (Print) -IS - 0163-8343 (Linking) -VI - 29 -IP - 2 -DP - 2007 Mar-Apr -TI - The association of depression and anxiety with medical symptom burden in patients - with chronic medical illness. -PG - 147-55 -AB - BACKGROUND: Primary care patients with anxiety and depression often describe - multiple physical symptoms, but no systematic review has studied the effect of - anxiety and depressive comorbidity in patients with chronic medical illnesses. - METHODS: MEDLINE databases were searched from 1966 through 2006 using the - combined search terms diabetes, coronary artery disease (CAD), congestive heart - failure (CHF), asthma, COPD, osteoarthritis (OA), rheumatoid arthritis (RA), with - depression, anxiety and symptoms. Cross-sectional and longitudinal studies with - >100 patients were included as were all randomized controlled trials that measure - the impact of improving anxiety and depressive symptoms on medical symptom - outcomes. RESULTS: Thirty-one studies involving 16,922 patients met our inclusion - criteria. Patients with chronic medical illness and comorbid depression or - anxiety compared to those with chronic medical illness alone reported - significantly higher numbers of medical symptoms when controlling for severity of - medical disorder. Across the four categories of common medical disorders examined - (diabetes, pulmonary disease, heart disease, arthritis), somatic symptoms were at - least as strongly associated with depression and anxiety as were objective - physiologic measures. Two treatment studies also showed that improvement in - depression outcome was associated with decreased somatic symptoms without - improvement in physiologic measures. CONCLUSIONS: Accurate diagnosis of comorbid - depressive and anxiety disorders in patients with chronic medical illness is - essential in understanding the cause and in optimizing the management of somatic - symptom burden. -FAU - Katon, Wayne -AU - Katon W -AD - Department of Psychiatry, University of Washington School of Medicine, Seattle, - WA 98195-6560, USA. wkaton@u.washington.edu -FAU - Lin, Elizabeth H B -AU - Lin EH -FAU - Kroenke, Kurt -AU - Kroenke K -LA - eng -GR - MH-067587/MH/NIMH NIH HHS/United States -GR - MH-069741/MH/NIMH NIH HHS/United States -GR - MH-071268/MH/NIMH NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Systematic Review -PL - United States -TA - Gen Hosp Psychiatry -JT - General hospital psychiatry -JID - 7905527 -SB - IM -MH - Adult -MH - Anxiety/*epidemiology -MH - Chronic Disease/*epidemiology/*psychology -MH - Comorbidity -MH - *Cost of Illness -MH - Depression/*epidemiology -MH - Female -MH - *Health Status -MH - Humans -MH - Male -MH - Surveys and Questionnaires -RF - 82 -EDAT- 2007/03/06 09:00 -MHDA- 2007/05/09 09:00 -CRDT- 2007/03/06 09:00 -PHST- 2006/10/20 00:00 [received] -PHST- 2006/11/27 00:00 [accepted] -PHST- 2007/03/06 09:00 [pubmed] -PHST- 2007/05/09 09:00 [medline] -PHST- 2007/03/06 09:00 [entrez] -AID - S0163-8343(06)00220-9 [pii] -AID - 10.1016/j.genhosppsych.2006.11.005 [doi] -PST - ppublish -SO - Gen Hosp Psychiatry. 2007 Mar-Apr;29(2):147-55. doi: - 10.1016/j.genhosppsych.2006.11.005. - -PMID- 22560578 -OWN - NLM -STAT- MEDLINE -DCOM- 20120727 -LR - 20131121 -IS - 1557-8240 (Electronic) -IS - 0031-3955 (Linking) -VI - 59 -IP - 2 -DP - 2012 Apr -TI - Kawasaki disease. -PG - 425-45 -LID - 10.1016/j.pcl.2012.03.009 [doi] -AB - Kawasaki disease is a systemic vasculitis and the leading cause of acquired heart - disease in North American and Japanese children. The epidemiology, cause, and - clinical characteristics of this disease are reviewed. The diagnostic challenge - of Kawasaki disease and its implications for coronary artery outcomes are - discussed, as are the recommended treatment, ongoing treatment controversies, - concerns associated with treatment resistance, and the importance of ongoing - follow up. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Scuccimarri, Rosie -AU - Scuccimarri R -AD - Division of Pediatric Rheumatology, Department of Pediatrics, Montreal Children's - Hospital, McGill University, 2300 Tupper, Room C-505, Montreal, Quebec H3H 1P3, - Canada. rosie.scuccimarri@muhc.mcgill.ca -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Pediatr Clin North Am -JT - Pediatric clinics of North America -JID - 0401126 -RN - 0 (Adrenal Cortex Hormones) -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) -RN - 0 (Immunoglobulins, Intravenous) -RN - 0 (Immunologic Factors) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Adrenal Cortex Hormones/therapeutic use -MH - Anti-Inflammatory Agents/therapeutic use -MH - Anti-Inflammatory Agents, Non-Steroidal/therapeutic use -MH - Aspirin/therapeutic use -MH - Child -MH - Humans -MH - Immunoglobulins, Intravenous/therapeutic use -MH - Immunologic Factors/therapeutic use -MH - *Mucocutaneous Lymph Node Syndrome/diagnosis/drug therapy/epidemiology/etiology -MH - Risk Factors -EDAT- 2012/05/09 06:00 -MHDA- 2012/07/28 06:00 -CRDT- 2012/05/08 06:00 -PHST- 2012/05/08 06:00 [entrez] -PHST- 2012/05/09 06:00 [pubmed] -PHST- 2012/07/28 06:00 [medline] -AID - S0031-3955(12)00010-7 [pii] -AID - 10.1016/j.pcl.2012.03.009 [doi] -PST - ppublish -SO - Pediatr Clin North Am. 2012 Apr;59(2):425-45. doi: 10.1016/j.pcl.2012.03.009. - -PMID- 24490256 -OWN - NLM -STAT- MEDLINE -DCOM- 20140521 -LR - 20161128 -IS - 1438-9010 (Electronic) -IS - 1438-9010 (Linking) -VI - 185 -IP - 10 -DP - 2013 Oct -TI - Role of preprocedural computed tomography in transcatheter aortic valve - implantation. -PG - 941-9 -AB - Transcatheter aortic valve implantation (TAVI) is currently considered an - acceptable alternative for the treatment of patients with severe aortic stenosis - and a high perioperative risk or a contraindication for open surgery. The benefit - of TAVI significantly outweighs the risk of the procedure in patients requiring - treatment that are not suitable for open surgery, and leads to a lower mortality - in the one-year follow-up. The absence of a direct view of the aortic root and - valve remains a challenge for the transcatheter approach. While direct inspection - of the aortic valve during open surgery allows an adequate prosthesis choice, it - is crucial for TAVI to know the individual anatomical details prior to the - procedure in order to assure adequate planning of the procedure and proper - prosthesis choice and patient selection. Among the imaging modalities available - for the evaluation of patients prior to TAVI, computed tomography (CT) plays a - central role in patient selection. CT reliably visualizes the dimensions of the - aortic root and allows a proper choice of the prosthesis size. The morphology of - the access path and relevant comorbidities can be assessed. The present review - summarizes the current state of knowledge regarding the value of CT in the - evaluation of patients prior to TAVI. CT plays a central role in patient - selection and planning prior to TAVI. CT reliably detects the dimensions of the - aortic root including the size of the aortic annulus, the degree of valve - calcification and the morphology of the access routes. KEY POINTS: CT plays a - central role in patient selection and planning prior to TAVI. CT reliably detects - the dimensions of the aortic root including the size of the aortic annulus, the - degree of valve calcification and the morphology of the access routes. CT - provides a more accurate measurement of the aortic annulus than 2D TEE and CT is - the only imaging modality that allows a risk assessment for paravalvular leakages - based on the calcification of the aortic valve. -FAU - Lehmkuhl, L -AU - Lehmkuhl L -FAU - Foldyna, B -AU - Foldyna B -FAU - Haensig, M -AU - Haensig M -FAU - von Aspern, K -AU - von Aspern K -FAU - Lücke, C -AU - Lücke C -FAU - Andres, C -AU - Andres C -FAU - Grothoff, M -AU - Grothoff M -FAU - Riese, F -AU - Riese F -FAU - Nitzsche, S -AU - Nitzsche S -FAU - Holzhey, D -AU - Holzhey D -FAU - Linke, A -AU - Linke A -FAU - Mohr, F-W -AU - Mohr FW -FAU - Gutberlet, M -AU - Gutberlet M -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Rofo -JT - RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin -JID - 7507497 -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Aorta, Abdominal/diagnostic imaging -MH - Aortic Valve/*diagnostic imaging/*surgery -MH - Aortic Valve Stenosis/*diagnostic imaging/*surgery -MH - Calcinosis/diagnostic imaging/surgery -MH - Cardiac Catheterization/*methods -MH - Coronary Angiography -MH - Coronary Stenosis/diagnostic imaging/surgery -MH - Female -MH - Femoral Artery/diagnostic imaging -MH - Heart Valve Prosthesis Implantation/*methods -MH - Humans -MH - Iliac Artery/diagnostic imaging -MH - Image Interpretation, Computer-Assisted/*methods -MH - Imaging, Three-Dimensional/*methods -MH - Intraoperative Complications/diagnostic imaging/surgery -MH - Male -MH - Patient Selection -MH - Preoperative Care/*methods -MH - Prosthesis Design -MH - Prosthesis Fitting/methods -MH - Sinus of Valsalva/diagnostic imaging/surgery -MH - Tomography, X-Ray Computed/*methods -EDAT- 2014/02/04 06:00 -MHDA- 2014/05/23 06:00 -CRDT- 2014/02/04 06:00 -PHST- 2014/02/04 06:00 [entrez] -PHST- 2014/02/04 06:00 [pubmed] -PHST- 2014/05/23 06:00 [medline] -PST - ppublish -SO - Rofo. 2013 Oct;185(10):941-9. - -PMID- 23877550 -OWN - NLM -STAT- MEDLINE -DCOM- 20131203 -LR - 20221207 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 14 -IP - 7-8 -DP - 2013 Jul-Aug -TI - [Ischemic heart disease and depression: an underestimated clinical association]. -PG - 526-37 -LID - 10.1714/1308.14461 [doi] -AB - Patients with acute or chronic ischemic heart disease have a high incidence of - depression, and a variable proportion of patients (ranging from 14% to 47%) - suffer from major or subclinical depression. In addition, chronic depression has - been shown to be associated with the development or progression of coronary - atherosclerosis. Besides a poor quality of life, depressive symptoms in patients - with ischemic heart disease result in a poor prognosis, as cardiovascular event - rates are 2-2.5 times higher than in their counterparts without depressive - symptoms. A variety of pathogenetic mechanisms may play a role, including - pathophysiological (dysfunction of the autonomic nervous system or - hypothalamic-pituitary-adrenal axis, platelet hyperaggregability, inflammation, - endothelial dysfunction and genetic predisposition) and behavioral mechanisms - (inadequate therapy adherence, obesity, smoking, sedentary lifestyle). However, - in patients with ischemic heart disease, depression often goes undiagnosed or - untreated. Several screening procedures including questionnaires for patients - with heart disease, along with the help of a psychiatrist, may facilitate not - only the diagnosis of depressive symptoms but also the pharmacological and/or - physiotherapeutic management. The use of tricyclic antidepressant agents should - be avoided in patients with heart disease, whereas selective serotonin reuptake - inhibitors have been shown to be safe in this patient population. However, no - evidence is available to support that use of these drugs is associated with a - reduced risk of cardiovascular events at follow-up. Psychotherapy proved to be - effective in reducing depressive symptoms but ineffective in improving prognosis. - In this review, epidemiology and pathophysiology of depression in patients with - ischemic heart disease are described, with a focus on stratification of - depressive symptoms and potential therapeutic strategies. -FAU - Pizzi, Carmine -AU - Pizzi C -AD - Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università - Alma Mater Studiorum, Bologna, Italy. -FAU - Santarella, Luigi -AU - Santarella L -FAU - Manfrini, Olivia -AU - Manfrini O -FAU - Chiavaroli, Martina -AU - Chiavaroli M -FAU - Agushi, Erjon -AU - Agushi E -FAU - Cordioli, Elvira -AU - Cordioli E -FAU - Costa, Grazia Maria -AU - Costa GM -FAU - Bugiardini, Raffaele -AU - Bugiardini R -LA - ita -PT - Journal Article -PT - Review -TT - Cardiopatia ischemica e depressione: una realtà sottostimata. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -RN - 0 (Antidepressive Agents) -RN - 0 (Antidepressive Agents, Tricyclic) -RN - 0 (Serotonin Uptake Inhibitors) -RN - 333DO1RDJY (Serotonin) -SB - IM -MH - Antidepressive Agents/therapeutic use -MH - Antidepressive Agents, Tricyclic -MH - Autonomic Nervous System/physiopathology -MH - Chronic Disease -MH - Comorbidity -MH - Contraindications -MH - Delayed Diagnosis -MH - Depression/diagnosis/drug therapy/*epidemiology -MH - Depressive Disorder/diagnosis/drug therapy/*epidemiology/physiopathology -MH - Endothelium, Vascular/physiopathology -MH - Genetic Predisposition to Disease -MH - Humans -MH - Hypothalamo-Hypophyseal System/physiopathology -MH - Inflammation -MH - Life Style -MH - Myocardial Ischemia/*epidemiology/physiopathology/psychology -MH - Pituitary-Adrenal System/physiopathology -MH - Platelet Activation -MH - Practice Guidelines as Topic -MH - Prognosis -MH - Quality of Life -MH - Randomized Controlled Trials as Topic -MH - Serotonin/physiology -MH - Selective Serotonin Reuptake Inhibitors/therapeutic use -EDAT- 2013/07/24 06:00 -MHDA- 2013/12/16 06:00 -CRDT- 2013/07/24 06:00 -PHST- 2013/07/24 06:00 [entrez] -PHST- 2013/07/24 06:00 [pubmed] -PHST- 2013/12/16 06:00 [medline] -AID - 10.1714/1308.14461 [doi] -PST - ppublish -SO - G Ital Cardiol (Rome). 2013 Jul-Aug;14(7-8):526-37. doi: 10.1714/1308.14461. - -PMID- 21414470 -OWN - NLM -STAT- MEDLINE -DCOM- 20110516 -LR - 20250529 -IS - 1873-1740 (Electronic) -IS - 0033-0620 (Print) -IS - 0033-0620 (Linking) -VI - 53 -IP - 5 -DP - 2011 Mar-Apr -TI - Air pollution and cardiovascular disease in the Multi-Ethnic Study of - Atherosclerosis. -PG - 353-60 -LID - 10.1016/j.pcad.2011.02.001 [doi] -AB - Research to date demonstrates a relationship between exposure to ambient air - pollutants and cardiovascular disease (CVD). Many studies have shown associations - between short-term exposures to elevated levels of air pollutants and CVD events, - and several cohort studies suggest effects of long-term exposure on - cardiovascular mortality, coronary heart disease events, and stroke. The biologic - mechanisms underlying this long-term exposure relationship are not entirely clear - but are hypothesized to include systemic inflammation, autonomic nervous system - imbalance, changes in vascular compliance, altered cardiac structure, and - development of atherosclerosis. The Multi-Ethnic Study of Atherosclerosis - provides an especially well-characterized population in which to investigate the - relationship between air pollution and CVD and to explore these biologic - pathways. This article reviews findings reported to date within this cohort and - summarizes the aims and anticipated contributions of a major ancillary study, the - Multi-Ethnic Study of Atherosclerosis and Air Pollution. -CI - Copyright © 2011. Published by Elsevier Inc. -FAU - Gill, Edward A -AU - Gill EA -AD - Department of Medicine, University of Washington, Seattle, WA 98105, USA. - eagill@u.washington.edu -FAU - Curl, Cynthia L -AU - Curl CL -FAU - Adar, Sara D -AU - Adar SD -FAU - Allen, Ryan W -AU - Allen RW -FAU - Auchincloss, Amy H -AU - Auchincloss AH -FAU - O'Neill, Marie S -AU - O'Neill MS -FAU - Park, Sung Kyun -AU - Park SK -FAU - Van Hee, Victor C -AU - Van Hee VC -FAU - Diez Roux, Ana V -AU - Diez Roux AV -FAU - Kaufman, Joel D -AU - Kaufman JD -LA - eng -GR - HL071205/HL/NHLBI NIH HHS/United States -GR - R01 HL071251/HL/NHLBI NIH HHS/United States -GR - HL071258-59/HL/NHLBI NIH HHS/United States -GR - N01 HC095169/HL/NHLBI NIH HHS/United States -GR - N01-HC-95163/HC/NHLBI NIH HHS/United States -GR - K24ES013195/ES/NIEHS NIH HHS/United States -GR - N01-HC-95159/HC/NHLBI NIH HHS/United States -GR - P50 ES015915/ES/NIEHS NIH HHS/United States -GR - HL071251-52/HL/NHLBI NIH HHS/United States -GR - P30 ES007033/ES/NIEHS NIH HHS/United States -GR - N01-HC-95160/HC/NHLBI NIH HHS/United States -GR - P30 ES017885/ES/NIEHS NIH HHS/United States -GR - R01 HL071205/HL/NHLBI NIH HHS/United States -GR - N01-HC-95161/HC/NHLBI NIH HHS/United States -GR - N01 HC095165/HL/NHLBI NIH HHS/United States -GR - K23 ES019575/ES/NIEHS NIH HHS/United States -GR - N01-HC-95162/HC/NHLBI NIH HHS/United States -GR - R01 HL077612/HL/NHLBI NIH HHS/United States -GR - K24 ES013195/ES/NIEHS NIH HHS/United States -GR - P30ES07033/ES/NIEHS NIH HHS/United States -GR - N01-HC-95165/HC/NHLBI NIH HHS/United States -GR - HL070151/HL/NHLBI NIH HHS/United States -GR - N01 HC095159/HL/NHLBI NIH HHS/United States -GR - N01-HC-95169/HC/NHLBI NIH HHS/United States -GR - N01-HC-95164/HC/NHLBI NIH HHS/United States -GR - R01 HL071258/HL/NHLBI NIH HHS/United States -GR - P50ES015915/ES/NIEHS NIH HHS/United States -PT - Journal Article -PT - Multicenter Study -PT - Research Support, N.I.H., Extramural -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - United States -TA - Prog Cardiovasc Dis -JT - Progress in cardiovascular diseases -JID - 0376442 -RN - 0 (Particulate Matter) -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Cardiovascular Diseases/ethnology/*etiology/physiopathology -MH - *Ethnicity/statistics & numerical data -MH - Evidence-Based Medicine -MH - Female -MH - Humans -MH - Inhalation Exposure -MH - Male -MH - Middle Aged -MH - Particulate Matter/*adverse effects -MH - Public Health -MH - Risk Assessment -MH - Risk Factors -MH - United States/epidemiology -PMC - PMC4016948 -MID - NIHMS576684 -EDAT- 2011/03/19 06:00 -MHDA- 2011/05/17 06:00 -PMCR- 2014/05/11 -CRDT- 2011/03/19 06:00 -PHST- 2011/03/19 06:00 [entrez] -PHST- 2011/03/19 06:00 [pubmed] -PHST- 2011/05/17 06:00 [medline] -PHST- 2014/05/11 00:00 [pmc-release] -AID - S0033-0620(11)00018-1 [pii] -AID - 10.1016/j.pcad.2011.02.001 [doi] -PST - ppublish -SO - Prog Cardiovasc Dis. 2011 Mar-Apr;53(5):353-60. doi: 10.1016/j.pcad.2011.02.001. - -PMID- 16418253 -OWN - NLM -STAT- MEDLINE -DCOM- 20060331 -LR - 20220321 -IS - 1527-1323 (Electronic) -IS - 0271-5333 (Linking) -VI - 26 -IP - 1 -DP - 2006 Jan-Feb -TI - Cardiovascular complications of human immunodeficiency virus infection. -PG - 213-31 -AB - The heart and great vessels are not the sites most frequently affected by - opportunistic infections and neoplastic processes in patients with acquired - immune deficiency syndrome (AIDS). However, cardiovascular complications occur in - a significant number of such patients and are the immediate cause of death in - some. The spectrum of cardiovascular complications of AIDS that may be depicted - at imaging includes dilated cardiomyopathy, pericardial effusion, human - immunodeficiency virus-associated pulmonary hypertension, endocarditis, - thrombosis, embolism, vasculitis, coronary artery disease, aneurysm, and cardiac - involvement in AIDS-related tumors. To aid accurate diagnosis and appropriate - treatment planning, radiologists should be familiar with the imaging appearance - of each of these complications. -CI - (c) RSNA, 2006. -FAU - Restrepo, Carlos S -AU - Restrepo CS -AD - Department of Radiology, Louisiana State University Health Sciences Center, 1542 - Tulane Ave, Room 212, New Orleans, LA 70112, USA. crestr@lsuhsc.edu -FAU - Diethelm, Lisa -AU - Diethelm L -FAU - Lemos, Julio A -AU - Lemos JA -FAU - Velásquez, Enrique -AU - Velásquez E -FAU - Ovella, Ty A -AU - Ovella TA -FAU - Martinez, Santiago -AU - Martinez S -FAU - Carrillo, Jorge -AU - Carrillo J -FAU - Lemos, Diego F -AU - Lemos DF -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Radiographics -JT - Radiographics : a review publication of the Radiological Society of North - America, Inc -JID - 8302501 -SB - IM -MH - Adult -MH - Cardiovascular Diseases/*diagnosis/*etiology -MH - Endocarditis, Bacterial/diagnosis/diagnostic imaging/etiology -MH - Female -MH - HIV Infections/*complications -MH - Heart Neoplasms/diagnosis/etiology -MH - Humans -MH - Hypertension, Pulmonary/diagnosis/diagnostic imaging/etiology -MH - Male -MH - Middle Aged -MH - Tomography, X-Ray Computed -MH - Ultrasonography -RF - 88 -EDAT- 2006/01/19 09:00 -MHDA- 2006/04/01 09:00 -CRDT- 2006/01/19 09:00 -PHST- 2006/01/19 09:00 [pubmed] -PHST- 2006/04/01 09:00 [medline] -PHST- 2006/01/19 09:00 [entrez] -AID - 26/1/213 [pii] -AID - 10.1148/rg.261055058 [doi] -PST - ppublish -SO - Radiographics. 2006 Jan-Feb;26(1):213-31. doi: 10.1148/rg.261055058. - -PMID- 16466323 -OWN - NLM -STAT- MEDLINE -DCOM- 20060614 -LR - 20181203 -IS - 0277-0008 (Print) -IS - 0277-0008 (Linking) -VI - 26 -IP - 2 -DP - 2006 Feb -TI - Implications of rosiglitazone and pioglitazone on cardiovascular risk in patients - with type 2 diabetes mellitus. -PG - 168-81 -AB - Clinical data suggest that thiazolidinediones--specifically, rosiglitazone and - pioglitazone--may improve cardiovascular risk factors through multiple - mechanisms. Low insulin sensitivity has been described as an independent risk - factor for coronary artery disease and cerebrovascular disease. Patients with - insulin resistance often have several known risk factors, such as obesity, - dyslipidemia, and hypertension. Other emerging risk factors may be prevalent in - patients with insulin resistance, such as hyperinsulinemia, elevated C-reactive - protein, elevated plasminogen activator inhibitor levels, and small, dense, - low-density lipoproteins. The only available drug class that primarily targets - insulin resistance is the thiazolidinediones. These drugs have shown efficacy in - affecting surrogate markers of cardiovascular risk in patients with diabetes - mellitus. Alterations in these risk factors are likely due to their effects on - improving insulin sensitivity and/or glycemic control. Trials to assess whether - thiazolidinediones actually reduce cardiovascular outcomes are continuing. -FAU - Irons, Brian K -AU - Irons BK -AD - Department of Pharmacy Practice, School of Pharmacy, Texas Tech University Health - Sciences Center, Amarillo, Texas 79430-8162, USA. brian.irons@ttuhsc.edu -FAU - Greene, Ronald Shane -AU - Greene RS -FAU - Mazzolini, Timothy A -AU - Mazzolini TA -FAU - Edwards, Krystal L -AU - Edwards KL -FAU - Sleeper, Rebecca B -AU - Sleeper RB -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Pharmacotherapy -JT - Pharmacotherapy -JID - 8111305 -RN - 0 (Hypoglycemic Agents) -RN - 0 (Thiazolidinediones) -RN - 05V02F2KDG (Rosiglitazone) -RN - X4OV71U42S (Pioglitazone) -SB - IM -CIN - Pharmacotherapy. 2006 Jul;26(7):1049; discussion 1049-50. doi: - 10.1592/phco.26.7.1049. PMID: 16803430 -MH - Cardiovascular Diseases/*epidemiology/etiology/prevention & control -MH - Diabetes Complications/*epidemiology/prevention & control -MH - Diabetes Mellitus, Type 2/*drug therapy -MH - Heart Failure/epidemiology/etiology -MH - Humans -MH - Hypoglycemic Agents/adverse effects/*therapeutic use -MH - Pioglitazone -MH - Risk Assessment -MH - Rosiglitazone -MH - Thiazolidinediones/adverse effects/*therapeutic use -MH - Treatment Outcome -RF - 136 -EDAT- 2006/02/10 09:00 -MHDA- 2006/06/15 09:00 -CRDT- 2006/02/10 09:00 -PHST- 2006/02/10 09:00 [pubmed] -PHST- 2006/06/15 09:00 [medline] -PHST- 2006/02/10 09:00 [entrez] -AID - 10.1592/phco.26.2.168 [doi] -PST - ppublish -SO - Pharmacotherapy. 2006 Feb;26(2):168-81. doi: 10.1592/phco.26.2.168. - -PMID- 19897698 -OWN - NLM -STAT- MEDLINE -DCOM- 20100122 -LR - 20091109 -IS - 1558-7118 (Electronic) -IS - 1557-2625 (Linking) -VI - 22 -IP - 6 -DP - 2009 Nov-Dec -TI - Are angiotensin-converting enzyme inhibitors and angiotensin receptor blockers - especially useful for cardiovascular protection? -PG - 686-97 -LID - 10.3122/jabfm.2009.06.090094 [doi] -AB - PURPOSE: This article seeks to objectively review the clinical trial evidence to - determine whether angiotensin-converting enzyme inhibitors (ACEIs) and - angiotensin-receptor blockers (ARBs) have special cardiovascular protective - effects. METHODS: An objective review of the clinical trial evidence. RESULTS: - Clinical trials in hypertensive patients comparing ACEI and ARB with other drugs - generally showed no difference in the primary cardiovascular outcome (United - Kingdom Prospective Diabetes Study Group, Captopril Prevention Project, Swedish - Trial in Old Patients with Hypertension 2, Japan Multicenter Investigation for - Cardiovascular Diseases-B Randomized Trial, Antihypertensive and Lipid-Lowering - Treatment to Prevent Heart Attack Trial, Second Australian National Blood - Pressure Study Group, Valsartan Antihypertensive Long-Term Use Evaluation). Where - the primary, or major secondary, cardiovascular end-point favors one of the - treatment arms, it was always the arm with the lower achieved blood pressure that - saw the better clinical result as in Losartan Intervention For Endpoint Reduction - in Hypertension Study, Captopril Prevention Project, Antihypertensive and - Lipid-Lowering Treatment to Prevent Heart Attack Trial, and Valsartan - Antihypertensive Long-Term Use Evaluation. Trials comparing ACEI or ARB against - placebo in patients at high risk of cardiovascular events have not showed a - consistent result; cardiovascular outcomes were reduced in Heart Outcomes - Prevention Evaluation, European Trial on Reduction of Cardiac Events with - Perindopril in Stable Coronary Artery Disease, and the Jikei Heart Study, but - were not significantly reduced in Perindopril Protection Against Recurrent Stroke - Study, Comparison of Arnlodipine vs Enalapril to Limit Occurrences of Thrombosis - Trial, Prevention of Events with ACEIs Trial, Telmisartan Randomized Assessment - Study in ACE-Intolerant Subjects with Cardiovascular Disease Trial, and - Prevention Regimen for Effectively Avoiding Second Strokes Trial. In the Ongoing - Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial, - combining ACEIs with ARBs in high-risk patients did not reduce cardiovascular or - renal outcomes compared with ACEI monotherapy alone. This absence of a reduction - in cardiovascular outcome from the ACEI and ARB combination arm is further - evidence suggesting that these drugs do not have any special cardiovascular - protective effect. This objective review thus shows that the rennin-angiotensin - antagonists do not have special cardiovascular protective properties. CONCLUSION: - The key to reducing cardiovascular outcome is to appropriately control blood - pressure as well as to treat all other coronary risk factors. -FAU - Ong, Hean Teik -AU - Ong HT -AD - HT Ong Heart Clinic, Penang, Malaysia. htyl@streamyx.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Am Board Fam Med -JT - Journal of the American Board of Family Medicine : JABFM -JID - 101256526 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/*therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/*therapeutic use -MH - Cardiovascular Diseases/*prevention & control -MH - Evidence-Based Medicine -MH - Humans -MH - Randomized Controlled Trials as Topic -RF - 61 -EDAT- 2009/11/10 06:00 -MHDA- 2010/01/23 06:00 -CRDT- 2009/11/10 06:00 -PHST- 2009/11/10 06:00 [entrez] -PHST- 2009/11/10 06:00 [pubmed] -PHST- 2010/01/23 06:00 [medline] -AID - 22/6/686 [pii] -AID - 10.3122/jabfm.2009.06.090094 [doi] -PST - ppublish -SO - J Am Board Fam Med. 2009 Nov-Dec;22(6):686-97. doi: 10.3122/jabfm.2009.06.090094. - -PMID- 16945215 -OWN - NLM -STAT- MEDLINE -DCOM- 20061019 -LR - 20181113 -IS - 0161-6412 (Print) -IS - 1743-1328 (Electronic) -IS - 0161-6412 (Linking) -VI - 28 -IP - 6 -DP - 2006 Sep -TI - Interventions for heart disease and their effects on Alzheimer's disease. -PG - 630-6 -AB - OBJECTIVES: To review the contributions of cardiovascular disease to Alzheimer's - disease and vascular dementia. METHODS: Review of the literature. RESULTS: - Alzheimer's disease and vascular dementia both share significant risk - attributable to cardiovascular risk factors. Hypertension and - hypercholesterolemia at midlife are significant risk factors for both subsequent - dementia. Diabetes and obesity are also risk factors for dementia. Stressful - medical procedures, such as coronary artery bypass and graft operations also - appear to contribute to the risk of Alzheimer's disease. Apolipoprotein E is the - major risk factor for Alzheimer's disease. Apolipoprotein E does not appear to - contribute to Alzheimer's disease by increasing serum cholesterol, but it might - contribute to the disease through a mechanism involving both Abeta and an - increase in neuronal vulnerability to stress. DISCUSSION: The strong association - of cardiovascular risk factors with Alzheimer's disease and vascular dementia - suggest that these diseases share some biologic pathways in common. The - contribution of cardiovascular disease to Alzheimer's disease and vascular - dementia suggest that cardiovascular therapies might prove useful in treating or - preventing dementia. Antihypertensive medications appear to be beneficial in - preventing vascular dementia. Statins might be beneficial in preventing the - progression of dementia in subjects with Alzheimer's disease. -FAU - Wolozin, Benjamin -AU - Wolozin B -AD - Department of Pharmacology, Boston University School of Medicine, Boston, MA - 02118-2526, USA. bwolozin@bu.edu -FAU - Bednar, Martin M -AU - Bednar MM -LA - eng -GR - R01 AG017485/AG/NIA NIH HHS/United States -PT - Journal Article -PT - Review -PL - England -TA - Neurol Res -JT - Neurological research -JID - 7905298 -SB - IM -MH - Alzheimer Disease/*epidemiology/physiopathology/*therapy -MH - Cardiovascular Diseases/*epidemiology/physiopathology/*therapy -MH - *Cerebrovascular Circulation -MH - Humans -MH - Risk Factors -PMC - PMC3913064 -MID - NIHMS549671 -EDAT- 2006/09/02 09:00 -MHDA- 2006/10/20 09:00 -PMCR- 2014/02/04 -CRDT- 2006/09/02 09:00 -PHST- 2006/09/02 09:00 [pubmed] -PHST- 2006/10/20 09:00 [medline] -PHST- 2006/09/02 09:00 [entrez] -PHST- 2014/02/04 00:00 [pmc-release] -AID - 10.1179/016164106X130515 [doi] -PST - ppublish -SO - Neurol Res. 2006 Sep;28(6):630-6. doi: 10.1179/016164106X130515. - -PMID- 22689257 -OWN - NLM -STAT- MEDLINE -DCOM- 20130122 -LR - 20211021 -IS - 2193-6226 (Electronic) -IS - 2193-6218 (Linking) -VI - 107 -IP - 5 -DP - 2012 Jun -TI - [Acute heart failure]. -PG - 397-423; quiz 424-5 -LID - 10.1007/s00063-012-0118-x [doi] -AB - Acute decompensated heart failure (ADHF) is a major public health problem - throughout the world and its importance is continuing to grow. More than 50% of - ADHF patients have coronary artery disease, which is generally associated with a - history of hypertension. Recent data suggest that half of the patients presenting - with acute heart failure have preserved left ventricular systolic function. The - diagnosis of ADHF may be difficult at times, and the clinical assessment and - patient profiling is essential for appropriate therapy. Immediate therapeutic - goals are not only to improve symptoms, restore oxygenation and stabilize - hemodynamic conditions, but also to improve short- and long-term survival. In - addition to general supportive measures such as oxygen supplementation, - noninvasive ventilation, analgesia, diuretics, vasodilators together with - inotropic agents and/or vasopressors remain the cornerstone of therapy in - patients with ADHF. -FAU - Janssens, U -AU - Janssens U -AD - Klinik für Innere Medizin, St. Antonius Hospital, Dechant-Deckers-Straße 8, - 52249, Eschweiler, Deutschland. uwe.janssens@sah-eschweiler.de -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Akute Herzinsuffizienz. -DEP - 20120613 -PL - Germany -TA - Med Klin Intensivmed Notfmed -JT - Medizinische Klinik, Intensivmedizin und Notfallmedizin -JID - 101575086 -RN - 0 (Catecholamines) -RN - 0 (Diuretics) -RN - 0 (Vasodilator Agents) -SB - IM -MH - Acute Disease -MH - Aged -MH - Cardiac Output, Low/diagnosis/etiology/physiopathology/therapy -MH - Cardio-Renal Syndrome/diagnosis/etiology/physiopathology/therapy -MH - Catecholamines/therapeutic use -MH - Comorbidity -MH - Diuretics/therapeutic use -MH - Electrocardiography -MH - Female -MH - Heart Failure/diagnosis/etiology/physiopathology/*therapy -MH - Hemodynamics/physiology -MH - Humans -MH - *Intensive Care Units -MH - Male -MH - Monitoring, Physiologic/methods -MH - Prognosis -MH - Risk Factors -MH - Signal Processing, Computer-Assisted -MH - Vasodilator Agents/therapeutic use -EDAT- 2012/06/13 06:00 -MHDA- 2013/01/23 06:00 -CRDT- 2012/06/13 06:00 -PHST- 2012/05/07 00:00 [received] -PHST- 2012/05/14 00:00 [accepted] -PHST- 2012/06/13 06:00 [entrez] -PHST- 2012/06/13 06:00 [pubmed] -PHST- 2013/01/23 06:00 [medline] -AID - 10.1007/s00063-012-0118-x [doi] -PST - ppublish -SO - Med Klin Intensivmed Notfmed. 2012 Jun;107(5):397-423; quiz 424-5. doi: - 10.1007/s00063-012-0118-x. Epub 2012 Jun 13. - -PMID- 17181043 -OWN - NLM -STAT- MEDLINE -DCOM- 20070119 -LR - 20090213 -IS - 0003-9683 (Print) -IS - 0003-9683 (Linking) -VI - 99 -IP - 11 -DP - 2006 Nov -TI - [The heart and underwater diving]. -PG - 1115-9 -AB - Cardiovascular examination of a certain number of candidates for underwater - diving raises justifiable questions of aptitude. An indicative list of - contraindications has been proposed by the French Federation of Underwater - Studies and Sports but a physiopathological basis gives a better understanding of - what is involved. During diving, the haemodynamic changes due not only to the - exercise but also to cold immersion, hyperoxaemia and decompression impose the - absence of any symptomatic cardiac disease. Moreover, the vasoconstriction caused - by the cold and hyperoxaemia should incite great caution in both coronary and - hypertensive patients. The contraindication related to betablocker therapy is - controversial and the debate has not been settled in France. The danger of - drowning makes underwater diving hazardous in all pathologies carrying a risk of - syncope. Pacemaker patients should be carefully assessed and the depth of diving - limited. Finally, the presence of right-to-left intracardiac shunts increases the - risk of complications during decompressionand contraindicates underwater diving. - Patent foramen ovale is a special case but no special investigation is required - for its detection. The cardiologist examining candidates for underwater diving - should take all these factors into consideration because, although underwater - diving is a sport associated with an increased risk, each year there are more and - more people, with differing degrees of aptitude, who wish to practice it. -FAU - Lafay, V -AU - Lafay V -AD - Service de médecine du sport, hôpital Salvator, 249, bd de Sainte-Marguerite, - 13274 Marseille 09. vincent.lafay@medecins-saint-antoine.fr -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Coeur et plongée. -PL - France -TA - Arch Mal Coeur Vaiss -JT - Archives des maladies du coeur et des vaisseaux -JID - 0406011 -SB - IM -MH - Decompression Sickness/physiopathology -MH - Diving/*physiology -MH - Heart Conduction System/*physiopathology -MH - Humans -MH - Hyperoxia/blood/physiopathology -MH - Hypertension/*physiopathology -MH - Pulmonary Embolism/physiopathology -RF - 30 -EDAT- 2006/12/22 09:00 -MHDA- 2007/01/20 09:00 -CRDT- 2006/12/22 09:00 -PHST- 2006/12/22 09:00 [pubmed] -PHST- 2007/01/20 09:00 [medline] -PHST- 2006/12/22 09:00 [entrez] -PST - ppublish -SO - Arch Mal Coeur Vaiss. 2006 Nov;99(11):1115-9. - -PMID- 24175071 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20211021 -IS - 2048-0040 (Print) -IS - 2048-0040 (Electronic) -IS - 2048-0040 (Linking) -VI - 1 -IP - 5 -DP - 2012 Aug 10 -TI - Adrenomedullin and cardiovascular diseases. -LID - 10.1258/cvd.2012.012003 [doi] -LID - cvd.2012.012003 -AB - The cardiovascular system is regulated by the autonomic nervous system, the - renin-angiotensin-aldosterone system, nitric oxide (NO) and other factors - including neuropeptides. Research in neurohumoral factors has led to the - development of many cardiovascular drugs. Adrenomedullin (ADM), initially - isolated from the adrenal gland, has diverse physiological and pathophysiological - functions in the cardiovascular system. It is produced in many organs and tissues - including the vasculature. ADM has numerous actions, including vasodilation, - natriuresis, antiapoptosis and stimulation of NO production. It might play a - protective role in various cardiovascular pathologies, and its plasma level is - elevated in patients with hypertension and heart failure. Administration of ADM - is a possible therapeutic approach for treating cardiovascular diseases. A number - of studies have investigated the infusion of ADM in humans, which seems to be - benficial in heart failure and myocardial infarction. Instead of ADM infusion, - augmentation of its endogenous level is another possible strategy. Gene therapy - is feasible in animal models, but its application in humans is limited. At - present, the most promising clinical application of ADM is the use of the plasma - level of mid-regional proadrenomedullin as a biomarker in cardiovascular - diseases. It is a good marker of prognosis and survival in patients with coronary - aretery disease or heart failure. -FAU - Wong, Hoi Kin -AU - Wong HK -AD - Department of Medicine, University of Hong Kong , Hong Kong , China. -FAU - Cheung, Tommy Tsang -AU - Cheung TT -FAU - Cheung, Bernard M Y -AU - Cheung BM -LA - eng -PT - Journal Article -PT - Review -DEP - 20120810 -PL - England -TA - JRSM Cardiovasc Dis -JT - JRSM cardiovascular disease -JID - 101598607 -PMC - PMC3738363 -EDAT- 2012/01/01 00:00 -MHDA- 2012/01/01 00:01 -PMCR- 2012/08/10 -CRDT- 2013/11/01 06:00 -PHST- 2013/11/01 06:00 [entrez] -PHST- 2012/01/01 00:00 [pubmed] -PHST- 2012/01/01 00:01 [medline] -PHST- 2012/08/10 00:00 [pmc-release] -AID - 10.1258_cvd.2012.012003 [pii] -AID - 10.1258/cvd.2012.012003 [doi] -PST - epublish -SO - JRSM Cardiovasc Dis. 2012 Aug 10;1(5):cvd.2012.012003. doi: - 10.1258/cvd.2012.012003. - -PMID- 16916005 -OWN - NLM -STAT- MEDLINE -DCOM- 20060919 -LR - 20170214 -IS - 1479-9723 (Print) -IS - 1479-9723 (Linking) -VI - 3 -IP - 3 -DP - 2006 -TI - Determining the cause of dyspnoea: linguistic and biological descriptors. -PG - 117-22 -AB - Dyspnoea is the most common symptom of patients with cardio-respiratory diseases. - It is a generic term related to different pathophysiological abnormalities that - may result in different qualities of respiratory discomfort, defined by specific - verbal descriptors for a specific diagnosis. Often it is difficult to distinguish - the underlying pathology of dyspnoea, eg, either from chronic heart failure (CHF) - or from other respiratory causes. The discovery of the endocrine function of the - heart, as well as the development of accurate and feasible assay methods allow - the use of cardiac natriuretic hormones in the assessment of cardiovascular - diseases, namely acute coronary syndromes and heart failure. It is advisable to - measure cardiac natriuretic hormones in order to exclude or suggest the diagnosis - of CHF in patients with a suspicious diagnosis, but with ambiguous signs and - symptoms or manifestations that can be confused with other pathologies (like - chronic obstructive pulmonary disease). The most common symptom of patients with - cardio-respiratory diseases is dyspnoea, a 'difficult, laboured, uncomfortable - breathing'. Dyspnoea has been defined as 'a term used to characterize a - subjective experience of breathing discomfort that consists of qualitatively - distinct sensations that vary in intensity. The experience derives from - interactions among multiple physiological, psychological, social and - environmental factors, and may induce secondary physiological and behavioural - responses'. Breathlessness is characterized by measurable intensity and - qualitative dimensions, which may vary depending on the individual, the - underlying disease, and other circumstances.3 The neurophysiological basis of - dyspnoea relies on receptors in the airways lung parenchyma, respiratory muscles - together with chemoreceptors providing sensory feedback via vagal, phrenic and - intercostal nerves to the spinal cord, medulla and higher centres. Breathlessness - is based on different pathophysiolagical abnormalities that may result in - different qualities of respiratory discomfort, which are defined by specific - verbal descriptors related to a specific diagnosis. Nevertheless different - diseases may share the same descriptors. There is no clear relationship between - the qualitative descriptors of dyspnoea and the quantitative intensity among the - patient groups: different diseases may be distinguished by quality but not - intensity of the sensation. Differences in languages, in races, cultures, gender, - and in the manner in which concepts or symptoms are held can all influence the - idea, quality and intensity of dyspnoea. -FAU - Ambrosino, N -AU - Ambrosino N -FAU - Serradori, M -AU - Serradori M -LA - eng -PT - Editorial -PT - Review -PL - England -TA - Chron Respir Dis -JT - Chronic respiratory disease -JID - 101197408 -RN - 0 (Peptide Fragments) -RN - 0 (Protein Precursors) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Diagnosis, Differential -MH - Dyspnea/diagnosis/*etiology/physiopathology -MH - Heart/physiopathology -MH - Humans -MH - Natriuretic Peptide, Brain/blood -MH - Peptide Fragments/blood -MH - Prognosis -MH - Protein Precursors/blood -MH - Pulmonary Disease, Chronic Obstructive/physiopathology -RF - 63 -EDAT- 2006/08/19 09:00 -MHDA- 2006/09/20 09:00 -CRDT- 2006/08/19 09:00 -PHST- 2006/08/19 09:00 [pubmed] -PHST- 2006/09/20 09:00 [medline] -PHST- 2006/08/19 09:00 [entrez] -AID - 10.1191/1479972306cd110ra [doi] -PST - ppublish -SO - Chron Respir Dis. 2006;3(3):117-22. doi: 10.1191/1479972306cd110ra. - -PMID- 23064510 -OWN - NLM -STAT- MEDLINE -DCOM- 20130822 -LR - 20161125 -IS - 1469-445X (Electronic) -IS - 0958-0670 (Linking) -VI - 98 -IP - 3 -DP - 2013 Mar -TI - Imaging the healing murine myocardial infarct in vivo: ultrasound, magnetic - resonance imaging and fluorescence molecular tomography. -PG - 606-13 -LID - 10.1113/expphysiol.2012.064741 [doi] -AB - Improved understanding of the processes involved in infarct healing is required - for identification of novel therapeutic targets to limit infarct expansion and - consequent long-term ventricular remodelling after myocardial infarction. Infarct - healing can be modelled effectively in murine models of coronary artery ligation. - While imaging the murine heart is challenging due to its size and high rate of - contraction, advances in preclinical imaging now permit accurate assessment of - myocardial structure and function in vivo after myocardial infarction. - Furthermore, rapid development of a range of molecular probes for use in a number - of imaging modalities allows more detailed in vivo analysis of processes, - including inflammation, fibrosis and angiogenesis. Here we consider the practical - application of in vivo imaging by magnetic resonance imaging, ultrasound and - fluorescence molecular tomography for assessment of infarct healing in the mouse. -FAU - Gray, Gillian A -AU - Gray GA -AD - British Heart Foundation/University Centre for Cardiovascular Science, University - of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK. - gillian.gray@ed.ac.uk -FAU - White, Christopher I -AU - White CI -FAU - Thomson, Adrian -AU - Thomson A -FAU - Kozak, Agnieszka -AU - Kozak A -FAU - Moran, Carmel -AU - Moran C -FAU - Jansen, Maurits A -AU - Jansen MA -LA - eng -PT - Journal Article -PT - Review -DEP - 20121012 -PL - England -TA - Exp Physiol -JT - Experimental physiology -JID - 9002940 -SB - IM -MH - Animals -MH - Disease Models, Animal -MH - Magnetic Resonance Imaging/methods -MH - Mice -MH - Multimodal Imaging/methods -MH - Myocardial Infarction/diagnostic imaging/pathology/*therapy -MH - Positron-Emission Tomography -MH - Tomography, X-Ray Computed -MH - Ultrasonography -MH - Ventricular Remodeling -EDAT- 2012/10/16 06:00 -MHDA- 2013/08/24 06:00 -CRDT- 2012/10/16 06:00 -PHST- 2012/10/16 06:00 [entrez] -PHST- 2012/10/16 06:00 [pubmed] -PHST- 2013/08/24 06:00 [medline] -AID - expphysiol.2012.064741 [pii] -AID - 10.1113/expphysiol.2012.064741 [doi] -PST - ppublish -SO - Exp Physiol. 2013 Mar;98(3):606-13. doi: 10.1113/expphysiol.2012.064741. Epub - 2012 Oct 12. - -PMID- 24392312 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20220310 -IS - 2220-3230 (Print) -IS - 2220-3230 (Electronic) -IS - 2220-3230 (Linking) -VI - 3 -IP - 4 -DP - 2013 Dec 24 -TI - Exercise after heart transplantation: An overview. -PG - 78-90 -LID - 10.5500/wjt.v3.i4.78 [doi] -AB - While life expectancy is greatly improved after a heart transplant, survival is - still limited, and compared to the general population, the exercise capacity and - health-related quality of life of heart transplant recipients are reduced. - Increased exercise capacity is associated with a better prognosis. However, - although several studies have documented positive effects of exercise after heart - transplantation (HTx), little is known about the type, frequency and intensity of - exercise that provides the greatest health benefits. Moreover, the long-term - effects of exercise on co-morbidities and survival are also unclear. Exercise - restrictions apply to patients with a denervated heart, and for decades, it was - believed that the transplanted heart remained denervated. This has since been - largely disproved, but despite the new knowledge, the exercise restrictions have - largely remained, and up-to-date guidelines on exercise prescription after HTx do - not exist. High-intensity, interval based aerobic exercise has repeatedly been - documented to have superior positive effects and health benefits compared to - moderate exercise. This applies to both healthy subjects as well as in several - patient groups, such as patients with metabolic syndrome, coronary artery disease - or heart failure. However, whether the effects of this type of exercise are also - applicable to heart transplant populations has not yet been fully established. - The purpose of this article is to give an overview of the current knowledge about - the exercise capacity and effect of exercise among heart transplant recipients - and to discuss future exercise strategies. -FAU - Nytrøen, Kari -AU - Nytrøen K -AD - Kari Nytrøen, Lars Gullestad, Department of Cardiology, Oslo University Hospital, - Rikshospitalet, 0424 Oslo, Norway. -FAU - Gullestad, Lars -AU - Gullestad L -AD - Kari Nytrøen, Lars Gullestad, Department of Cardiology, Oslo University Hospital, - Rikshospitalet, 0424 Oslo, Norway. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - World J Transplant -JT - World journal of transplantation -JID - 101608356 -PMC - PMC3879527 -OTO - NOTNLM -OT - Cardiac allograft vasculopathy -OT - Denervation -OT - Exercise -OT - Exercise capacity -OT - Heart transplant -OT - Maximum oxygen uptake -OT - Muscle strength -OT - Quality of life -OT - Reinnervation -EDAT- 2014/01/07 06:00 -MHDA- 2014/01/07 06:01 -PMCR- 2013/12/24 -CRDT- 2014/01/07 06:00 -PHST- 2013/06/13 00:00 [received] -PHST- 2013/07/15 00:00 [revised] -PHST- 2013/07/23 00:00 [accepted] -PHST- 2014/01/07 06:00 [entrez] -PHST- 2014/01/07 06:00 [pubmed] -PHST- 2014/01/07 06:01 [medline] -PHST- 2013/12/24 00:00 [pmc-release] -AID - 10.5500/wjt.v3.i4.78 [doi] -PST - ppublish -SO - World J Transplant. 2013 Dec 24;3(4):78-90. doi: 10.5500/wjt.v3.i4.78. - -PMID- 17669876 -OWN - NLM -STAT- MEDLINE -DCOM- 20070928 -LR - 20131121 -IS - 1569-9285 (Electronic) -IS - 1569-9285 (Linking) -VI - 6 -IP - 3 -DP - 2007 Jun -TI - What is the optimal level of anticoagulation in adult patients receiving warfarin - following implantation of a mechanical prosthetic mitral valve? -PG - 390-6 -AB - A best evidence topic in cardiac surgery was written according to a structured - protocol. The question addressed was what is the optimal target INR for warfarin - therapy in patients who have undergone implantation of a prosthetic mechanical - mitral heart valves? Altogether 894 papers were identified on Medline and 1235 on - Embase using the reported search including all major international guidelines. - Twelve papers and publications represented the best evidence on the topic. The - author, journal, date and country of publication, patient group studied, study - type, relevant outcomes, results and study weaknesses were tabulated. We conclude - that after implantation of new generation prosthetic mechanical mitral valves, - patients should receive warfarin to a target INR of 2.5-3.5. For older types of - valve the target INR should be 3.5-4.5. Warfarin therapy should be administered - to maintain stable INR values ensuring lowest possible variation in the intensity - of anticoagulation. In selected patients with a history of thromboembolic disease - and/or coronary artery disease warfarin therapy consideration should be given to - supplementing warfarin with low-dose aspirin. -FAU - Bayliss, Andrew -AU - Bayliss A -AD - Department of Cardiac Anaesthesia, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, - UK. -FAU - Faber, Peter -AU - Faber P -FAU - Dunning, Joel -AU - Dunning J -FAU - Ronald, Andrew -AU - Ronald A -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20070209 -PL - England -TA - Interact Cardiovasc Thorac Surg -JT - Interactive cardiovascular and thoracic surgery -JID - 101158399 -RN - 0 (Anticoagulants) -RN - 5Q7ZVV76EI (Warfarin) -SB - IM -MH - Anticoagulants/*administration & dosage -MH - *Heart Valve Prosthesis -MH - Hemorrhage/etiology/prevention & control -MH - Humans -MH - International Normalized Ratio -MH - Male -MH - Middle Aged -MH - Mitral Valve Insufficiency/*surgery -MH - Thromboembolism/etiology/prevention & control -MH - Warfarin/*administration & dosage -RF - 22 -EDAT- 2007/08/03 09:00 -MHDA- 2007/09/29 09:00 -CRDT- 2007/08/03 09:00 -PHST- 2007/08/03 09:00 [pubmed] -PHST- 2007/09/29 09:00 [medline] -PHST- 2007/08/03 09:00 [entrez] -AID - icvts.2007.152819 [pii] -AID - 10.1510/icvts.2007.152819 [doi] -PST - ppublish -SO - Interact Cardiovasc Thorac Surg. 2007 Jun;6(3):390-6. doi: - 10.1510/icvts.2007.152819. Epub 2007 Feb 9. - -PMID- 17052447 -OWN - NLM -STAT- MEDLINE -DCOM- 20061031 -LR - 20220716 -IS - 1534-6285 (Electronic) -IS - 1527-2737 (Linking) -VI - 7 -IP - 6 -DP - 2006 Nov -TI - Erectile dysfunction and cardiac disease: recommendations of the Second Princeton - Conference. -PG - 490-6 -AB - Erectile dysfunction (ED) has been linked increasingly to cardiovascular risk - factors and comorbidities. Considering the potential risk associated with sexual - activity, guidelines were developed (Princeton I) for assessment and management - of patients with varying degrees of cardiac risk. These guidelines were recently - updated (Princeton II) based on new data concerning the link between ED and - cardiovascular disease and the availability of additional phosphodiesterase type - 5 inhibitors (vardenafil, tadalafil). Despite the need for careful risk - assessment in all cases, sexual activity remains safe for the large majority of - patients. However, all patients presenting with complaints of ED should be - carefully assessed for the presence of cardiovascular risk factors (eg, obesity, - hypertension, hyperlipidemia). Risk-factor modification, including lifestyle - interventions (eg, exercise, weight loss) is strongly encouraged. Guidelines are - presented for the management of acute coronary syndromes in patients taking - phosphodiesterase type 5 inhibitors, including alternatives to the use of - nitrates for these patients. Other drug interactions and the cardiovascular - safety of testosterone replacement therapy are considered. -FAU - Rosen, Raymond C -AU - Rosen RC -AD - University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical - School, 671 Hoes Lane, Piscataway, NJ 08854, USA. rosen@umdnj.edu -FAU - Jackson, Graham -AU - Jackson G -FAU - Kostis, John B -AU - Kostis JB -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Urol Rep -JT - Current urology reports -JID - 100900943 -RN - 0 (Phosphodiesterase Inhibitors) -SB - IM -MH - Cardiovascular Diseases/complications -MH - Drug Interactions -MH - Erectile Dysfunction/*complications/drug therapy -MH - Heart Diseases/*complications -MH - Humans -MH - Male -MH - Phosphodiesterase Inhibitors/therapeutic use -MH - Practice Guidelines as Topic -MH - Risk Factors -RF - 38 -EDAT- 2006/10/21 09:00 -MHDA- 2006/11/01 09:00 -CRDT- 2006/10/21 09:00 -PHST- 2006/10/21 09:00 [pubmed] -PHST- 2006/11/01 09:00 [medline] -PHST- 2006/10/21 09:00 [entrez] -AID - 10.1007/s11934-006-0060-7 [doi] -PST - ppublish -SO - Curr Urol Rep. 2006 Nov;7(6):490-6. doi: 10.1007/s11934-006-0060-7. - -PMID- 19947886 -OWN - NLM -STAT- MEDLINE -DCOM- 20100727 -LR - 20240508 -IS - 1557-7422 (Electronic) -IS - 1043-0342 (Print) -IS - 1043-0342 (Linking) -VI - 21 -IP - 4 -DP - 2010 Apr -TI - Cardiac gene therapy: optimization of gene delivery techniques in vivo. -PG - 371-80 -LID - 10.1089/hum.2009.164 [doi] -AB - Vector-mediated cardiac gene therapy holds tremendous promise as a translatable - platform technology for treating many cardiovascular diseases. The ideal - technique is one that is efficient and practical, allowing for global cardiac - gene expression, while minimizing collateral expression in other organs. Here we - survey the available in vivo vector-mediated cardiac gene delivery - methods--including transcutaneous, intravascular, intramuscular, and - cardiopulmonary bypass techniques--with consideration of the relative merits and - deficiencies of each. Review of available techniques suggests that an optimal - method for vector-mediated gene delivery to the large animal myocardium would - ideally employ retrograde and/or anterograde transcoronary gene delivery,extended - vector residence time in the coronary circulation, an increased myocardial - transcapillary gradient using physical methods, increased endothelial - permeability with pharmacological agents, minimal collateral gene expression by - isolation of the cardiac circulation from the systemic, and have low - immunogenicity. -FAU - Katz, Michael G -AU - Katz MG -AD - Division of Cardiovascular Surgery, Department of Surgery, University of - Pennsylvania Medical Center, Philadelphia, PA 19104, USA. -FAU - Swain, JaBaris D -AU - Swain JD -FAU - White, Jennifer D -AU - White JD -FAU - Low, David -AU - Low D -FAU - Stedman, Hansell -AU - Stedman H -FAU - Bridges, Charles R -AU - Bridges CR -LA - eng -GR - 1-R01-HL083078-01A2/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - Hum Gene Ther -JT - Human gene therapy -JID - 9008950 -SB - IM -MH - Animals -MH - Cricetinae -MH - Disease Models, Animal -MH - Dogs -MH - *Gene Transfer Techniques -MH - Genetic Therapy/*methods -MH - Genetic Vectors -MH - Heart Failure/*therapy -MH - Humans -MH - Myocytes, Cardiac/metabolism -PMC - PMC2865214 -EDAT- 2009/12/02 06:00 -MHDA- 2010/07/28 06:00 -PMCR- 2011/04/01 -CRDT- 2009/12/02 06:00 -PHST- 2009/12/02 06:00 [entrez] -PHST- 2009/12/02 06:00 [pubmed] -PHST- 2010/07/28 06:00 [medline] -PHST- 2011/04/01 00:00 [pmc-release] -AID - 10.1089/hum.2009.164 [pii] -AID - 10.1089/hum.2009.164 [doi] -PST - ppublish -SO - Hum Gene Ther. 2010 Apr;21(4):371-80. doi: 10.1089/hum.2009.164. - -PMID- 19506318 -OWN - NLM -STAT- MEDLINE -DCOM- 20090924 -LR - 20220331 -IS - 1346-9843 (Print) -IS - 1346-9843 (Linking) -VI - 73 -IP - 7 -DP - 2009 Jul -TI - Why do we still not have cardioprotective drugs? -PG - 1171-7 -AB - Despite thousands of publications describing agents that limit infarct size in - animals, all we have available today is reperfusion therapy. In this review, we - examine why these drugs have not been translated into clinical practice. Many of - the first interventions tested in clinical trials were very controversial in - animal trials and their actual efficacy is still in question. Interventions based - on the preconditioning mechanism have been very reproducible in animals, but - clinical testing of them has just begun. Only approximately 25% of reperfused - patients have infarcts large enough to put them at risk of heart failure and - would require additional treatment. Inclusion of the 75% of patients with small - infarcts in treatment groups has greatly diluted the significance of data in past - clinical trials. Size of the risk zone has emerged as a reliable way to identify - the vulnerable 25%. Recent small-scale clinical trials using risk stratification - algorithms have shown clear infarct size limitation using ischemic and - pharmacological postconditioning, confirming that the human heart responds like - hearts of animal models. Most cardioprotectants have been studied in healthy - animals, but recent studies indicate that aging and diabetes, common in coronary - patients, do interfere with preconditioning-based interventions in animals. - Clearly more study is needed to identify which interventions are adversely - affected by comorbidities. -FAU - Downey, James M -AU - Downey JM -AD - Department of Physiology, College of Medicine, University of South Alabama, - Mobile, AL 36688, USA. jdowney@usouthal.edu -FAU - Cohen, Michael V -AU - Cohen MV -LA - eng -PT - Journal Article -PT - Review -DEP - 20090609 -PL - Japan -TA - Circ J -JT - Circulation journal : official journal of the Japanese Circulation Society -JID - 101137683 -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Algorithms -MH - Animals -MH - Cardiotonic Agents/*therapeutic use -MH - Disease Models, Animal -MH - Humans -MH - Ischemic Preconditioning, Myocardial -MH - Myocardial Infarction/pathology/*therapy -MH - Myocardial Reperfusion -MH - Myocardial Reperfusion Injury/pathology/*therapy -RF - 54 -EDAT- 2009/06/10 09:00 -MHDA- 2009/09/25 06:00 -CRDT- 2009/06/10 09:00 -PHST- 2009/06/10 09:00 [entrez] -PHST- 2009/06/10 09:00 [pubmed] -PHST- 2009/09/25 06:00 [medline] -AID - JST.JSTAGE/circj/CJ-09-0338 [pii] -AID - 10.1253/circj.cj-09-0338 [doi] -PST - ppublish -SO - Circ J. 2009 Jul;73(7):1171-7. doi: 10.1253/circj.cj-09-0338. Epub 2009 Jun 9. - -PMID- 18062896 -OWN - NLM -STAT- MEDLINE -DCOM- 20080410 -LR - 20160804 -IS - 1081-5589 (Print) -IS - 1081-5589 (Linking) -VI - 55 -IP - 7 -DP - 2007 Nov -TI - Intracardiac and intrarenal renin-angiotensin systems: mechanisms of - cardiovascular and renal effects. -PG - 341-59 -LID - 10.2310/6650.2007.00020 [doi] -AB - The renin-angiotensin system (RAS) is a hormonal system that controls body fluid - volume, blood pressure, and cardiovascular function in both health and disease. - Various tissues, including the heart and kidneys, possess individual locally - regulated RASs. In each RAS, the substrate protein angiotensinogen is cleaved by - the peptidases renin and angiotensin-converting enzyme to form the biologically - active product angiotensin II, which acts as an intracrine cardiac and renal - hormone. The components of each RAS, including aldosterone (ALDO), may be - produced locally and/or may be delivered by or sequestered from the circulation. - Overactivity of the cardiac RAS has been associated with cardiac diseases, - including cardiac hypertrophy due to volume and/or pressure overload, heart - failure, coronary artery disease with myocardial infarction, and hypertension. - Overactivity of the renal RAS has been associated with various kidney diseases, - including nephropathies and renal artery stenosis. The principal effects of an - overactive RAS include the generation of reactive oxygen species, which leads to - "oxidative stress," activation of the nuclear transcription factor kappaB, and - stimulation of pathways and genes that promote vasoconstriction, endothelial - dysfunction, cell hypertrophy, fibroblast proliferation, inflammation, excess - extracellular matrix deposition, atherosclerosis, and thrombosis. It has been - suggested that oxidative stress is the central mechanism underlying the - pathogenesis of RAS-related and ALDO-related chronic cardiovascular and renal - tissue injury and of cardiac arrhythmias and conduction disturbances. -FAU - Raizada, Veena -AU - Raizada V -AD - Department of Internal Medicine, University of New Mexico, Albuquerque, NM - 87131-0001, USA. vraizada@salud.unm.edu -FAU - Skipper, Betty -AU - Skipper B -FAU - Luo, Wentao -AU - Luo W -FAU - Griffith, Jeffrey -AU - Griffith J -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - J Investig Med -JT - Journal of investigative medicine : the official publication of the American - Federation for Clinical Research -JID - 9501229 -SB - IM -MH - Cardiovascular Diseases/*etiology -MH - Humans -MH - Kidney Diseases/*etiology -MH - Renin-Angiotensin System/*physiology -RF - 252 -EDAT- 2007/12/08 09:00 -MHDA- 2008/04/11 09:00 -CRDT- 2007/12/08 09:00 -PHST- 2007/12/08 09:00 [pubmed] -PHST- 2008/04/11 09:00 [medline] -PHST- 2007/12/08 09:00 [entrez] -AID - 10.2310/6650.2007.00020 [doi] -PST - ppublish -SO - J Investig Med. 2007 Nov;55(7):341-59. doi: 10.2310/6650.2007.00020. - -PMID- 18268924 -OWN - NLM -STAT- MEDLINE -DCOM- 20080325 -LR - 20240417 -IS - 1176-9106 (Print) -IS - 1178-2005 (Electronic) -IS - 1176-9106 (Linking) -VI - 2 -IP - 4 -DP - 2007 -TI - Perioperative medical management of patients with COPD. -PG - 493-515 -AB - Chronic obstructive pulmonary disease (COPD) and heart diseases are considered - independent risk factors for mortality and major cardiopulmonary complications - after surgery. Coronary artery disease, heart failure and COPD share common risk - factors and are often encountered,--isolated or combined--, in many surgical - candidates. Perioperative optimization of these high-risk patients deserves a - thorough understanding of the patient cardiopulmonary diseases as well as the - respiratory consequences of surgery and anesthesia. In contrast with cardiac risk - stratification where the extent of heart disease largely influences postoperative - cardiac outcome, surgical-related factors (ie, upper abdominal and intra-thoracic - procedures, duration of anesthesia, presence of a nasogastric tube) largely - dominate patient's comorbidities as risk factors for postoperative pulmonary - complications. Although most COPD patients tolerate tracheal intubation under - "smooth" anesthetic induction without serious adverse effects, regional - anesthetic blockade and application of laryngeal masks or non-invasive positive - pressure ventilation should be considered whenever possible, in order to provide - optimal pain control and to prevent upper airway injuries as well as lung - baro-volotrauma. Minimally-invasive procedures and modern multimodal analgesic - regimen are helpful to minimize the surgical stress response, to speed up the - physiological recovery process and to shorten the hospital stay. Reflex-induced - bronchoconstriction and hyperdynamic inflation during mechanical ventilation - could be prevented by using bronchodilating volatile anesthetics and adjusting - the ventilatory settings with long expiration times. Intraoperatively, the depth - of anesthesia, the circulatory volume and neuromuscular blockade should be - assessed with modem physiological monitoring tools to titrate the administration - of anesthetic agents, fluids and myorelaxant drugs. The recovery of postoperative - lung volume can be facilitated by patient's education and empowerment, lung - recruitment maneuvers, non-invasive pressure support ventilation and early - ambulation. -FAU - Licker, Marc -AU - Licker M -AD - Service d'Anesthésiologie, Hôpitaux Universitaires de Genève, Genève, - Switzerland. marc-joseph.licker@hcuge.ch -FAU - Schweizer, Alexandre -AU - Schweizer A -FAU - Ellenberger, Christoph -AU - Ellenberger C -FAU - Tschopp, Jean-Marie -AU - Tschopp JM -FAU - Diaper, John -AU - Diaper J -FAU - Clergue, François -AU - Clergue F -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Int J Chron Obstruct Pulmon Dis -JT - International journal of chronic obstructive pulmonary disease -JID - 101273481 -SB - IM -MH - Anesthesia -MH - Cardiovascular Diseases -MH - Humans -MH - Perioperative Care/*methods -MH - Postoperative Complications/mortality -MH - Pulmonary Disease, Chronic Obstructive/*surgery -MH - Switzerland -PMC - PMC2699974 -EDAT- 2008/02/14 09:00 -MHDA- 2008/03/26 09:00 -PMCR- 2007/12/01 -CRDT- 2008/02/14 09:00 -PHST- 2008/02/14 09:00 [pubmed] -PHST- 2008/03/26 09:00 [medline] -PHST- 2008/02/14 09:00 [entrez] -PHST- 2007/12/01 00:00 [pmc-release] -AID - copd-2-493 [pii] -PST - ppublish -SO - Int J Chron Obstruct Pulmon Dis. 2007;2(4):493-515. - -PMID- 23945013 -OWN - NLM -STAT- MEDLINE -DCOM- 20140428 -LR - 20211203 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Linking) -VI - 11 -IP - 8 -DP - 2013 Aug -TI - Therapeutic potential of genes in cardiac repair. -PG - 1015-28 -LID - 10.1586/14779072.2013.814867 [doi] -AB - Cardiovascular diseases remain the primary reason of premature death and - contribute to a major percentage of global patient morbidity. Recent knowledge in - the molecular mechanisms of myocardial complications have identified novel - therapeutic targets along with the availability of vectors that offer the chance - for designing gene therapy technique for protection and revival of the diseased - heart functions. Gene transfer procedure into the myocardium is demonstrated - through direct injection of plasmid DNA or through the coronary vasculature using - the direct or indirect delivery of viral vectors. Direct DNA injection to the - myocardium is reported to be of immense value in research studies that aims at - understanding the activities of various elements in myocardium. It is also deemed - vital for investigating the effect of the myocardial pathophysiology on - expression of the foreign genes that are transferred. Gene therapies have been - reported to heal cardiac pathologies such as myocardial ischemia, heart failure - and inherited myopathies in several animal models. The results obtained from - these animal studies have also encouraged a flurry of early clinical trials. This - translational research has been triggered by an enhanced understanding of the - biological mechanisms involved in tissue repair after ischemic injury. While - safety concerns take utmost priority in these trials, several combinational - therapies, various routes and dose of delivery are being tested before concrete - optimization and complete potential of gene therapy is convincingly understood. -FAU - Pal, Shripad N -AU - Pal SN -AD - Department of Surgery, Yong Loo Lin School of Medicine, National University of - Singapore, Singapore. -FAU - Kofidis, Theodoros -AU - Kofidis T -LA - eng -PT - Journal Article -PT - Retracted Publication -PT - Review -DEP - 20130814 -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -RN - 9007-49-2 (DNA) -SB - IM -RIN - Expert Rev Cardiovasc Ther. 2015 Jan;13(1):119. doi: - 10.1586/14779072.2014.986408. PMID: 25426991 -MH - Animals -MH - Cardiovascular Diseases/physiopathology/*therapy -MH - Clinical Trials as Topic -MH - DNA/administration & dosage -MH - Disease Models, Animal -MH - *Gene Targeting -MH - Gene Transfer Techniques -MH - Genetic Therapy/*methods -MH - Genetic Vectors -MH - Humans -MH - Myocardium/pathology -MH - Translational Research, Biomedical -EDAT- 2013/08/16 06:00 -MHDA- 2014/04/29 06:00 -CRDT- 2013/08/16 06:00 -PHST- 2013/08/16 06:00 [entrez] -PHST- 2013/08/16 06:00 [pubmed] -PHST- 2014/04/29 06:00 [medline] -AID - 10.1586/14779072.2013.814867 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2013 Aug;11(8):1015-28. doi: - 10.1586/14779072.2013.814867. Epub 2013 Aug 14. - -PMID- 19592143 -OWN - NLM -STAT- MEDLINE -DCOM- 20091002 -LR - 20250529 -IS - 1523-6838 (Electronic) -IS - 0272-6386 (Print) -IS - 0272-6386 (Linking) -VI - 54 -IP - 4 -DP - 2009 Oct -TI - Epidemiology, diagnosis, and management of depression in patients with CKD. -PG - 741-52 -LID - 10.1053/j.ajkd.2009.05.003 [doi] -AB - A 58-year-old Hispanic man who has been dialysis dependent for 2 years because of - diabetic nephropathy reports depressive symptoms during dialysis rounds. For the - past 6 weeks, he has had reduced energy and difficulty sleeping and - concentrating. He reports a loss of interest in his usual hobbies and family - activities and notes an increasing sense of feeling worthless and guilty. He - denies suicidal ideation. Medical history includes diabetic retinopathy and - neuropathy, coronary artery disease treated with 4-vessel coronary artery bypass - grafting 3 years ago, ischemic cardiomyopathy with an ejection fraction of 30%, - and cerebrovascular disease. His wife recently has been given a diagnosis of - breast cancer. His medications are aspirin, metoprolol, lisinopril, simvastatin, - sevelamer, and epoetin alfa. His blood pressure is 130/75 mm Hg, pulse is 65 - beats/min, and cardiac and pulmonary examination results are unremarkable. He is - interviewed by the social worker in the dialysis unit, who diagnoses clinical - depression by using standard Diagnostic and Statistical Manual of Mental - Disorders (Fourth Edition) (DSM IV) criteria. The patient refuses to discuss his - problems with the social worker and declines further psychiatric evaluation. His - nephrologist discusses a trial of antidepressant medication, but the patient - refuses to use additional medication. During the next month, the patient presents - with greater interdialytic weight gains and begins to come late for dialysis - sessions. He then presents to a dialysis session reporting dyspnea and orthopnea - and is found to have a 10-kg weight gain. On physical examination, blood pressure - is 196/96 mm Hg and he has increased jugular venous pressure and bibasilar - crackles. He is admitted to the hospital with a diagnosis of congestive heart - failure. -FAU - Hedayati, S Susan -AU - Hedayati SS -AD - Division of Nephrology, Department of Medicine, Veterans Affairs North Texas - Health Care System, Dallas, TX, USA. -FAU - Finkelstein, Fredric O -AU - Finkelstein FO -LA - eng -GR - P30 DK079328/DK/NIDDK NIH HHS/United States -GR - P30DK079328/DK/NIDDK NIH HHS/United States -PT - Case Reports -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -DEP - 20090709 -PL - United States -TA - Am J Kidney Dis -JT - American journal of kidney diseases : the official journal of the National Kidney - Foundation -JID - 8110075 -SB - IM -MH - Depression/complications/diagnosis/epidemiology/*etiology/*therapy -MH - Diabetic Nephropathies/*psychology/therapy -MH - Heart Failure/etiology -MH - Humans -MH - Kidney Failure, Chronic/*psychology/therapy -MH - Male -MH - Middle Aged -MH - Prevalence -MH - Renal Dialysis -MH - Renal Insufficiency, Chronic/*psychology/therapy -MH - Risk Factors -PMC - PMC3217258 -MID - NIHMS332957 -EDAT- 2009/07/14 09:00 -MHDA- 2009/10/03 06:00 -PMCR- 2011/11/16 -CRDT- 2009/07/14 09:00 -PHST- 2009/02/10 00:00 [received] -PHST- 2009/05/06 00:00 [accepted] -PHST- 2009/07/14 09:00 [entrez] -PHST- 2009/07/14 09:00 [pubmed] -PHST- 2009/10/03 06:00 [medline] -PHST- 2011/11/16 00:00 [pmc-release] -AID - S0272-6386(09)00757-4 [pii] -AID - 10.1053/j.ajkd.2009.05.003 [doi] -PST - ppublish -SO - Am J Kidney Dis. 2009 Oct;54(4):741-52. doi: 10.1053/j.ajkd.2009.05.003. Epub - 2009 Jul 9. - -PMID- 24083626 -OWN - NLM -STAT- MEDLINE -DCOM- 20140829 -LR - 20181202 -IS - 1473-4877 (Electronic) -IS - 0300-7995 (Linking) -VI - 30 -IP - 1 -DP - 2014 Jan -TI - Long-term clinical efficacy and safety of adding cilostazol to dual antiplatelet - therapy for patients undergoing PCI: a meta-analysis of randomized trials with - adjusted indirect comparisons. -PG - 37-49 -LID - 10.1185/03007995.2013.850067 [doi] -AB - OBJECTIVE: To assess the long-term clinical efficacy and safety of adding - cilostazol to aspirin plus clopidogrel (triple antiplatelet therapy, TAT) in - patients undergoing percutaneous coronary intervention (PCI) and explore its role - in the era of new generation adenosine diphosphate (ADP)-receptor antagonists. - METHODS: PUBMED, EMBASE, and the Cochrane Central Register of Controlled Trials - were searched for randomized controlled trials (RCTs) comparing TAT versus dual - antiplatelet therapy (DAT), followed by a manual search. Then, a meta-analysis of - RCTs comparing TAT versus standard DAT in patients undergoing PCI was performed. - Furthermore, indirect comparisons of TAT versus new generation ADP-receptor - antagonist based DAT (prasugrel or ticagrelor based DAT) were undertaken, with - standard DAT as a common comparator. The included end-points were major adverse - cardiovascular event (MACE), target lesion revascularization (TLR), target vessel - revascularization (TVR), death, myocardial infarction (MI), stent thrombosis, - bleeding and other drug adverse events. RESULTS: Twelve RCTs with a total of - 31,789 patients were included. Compared with standard DAT (n = 2551), TAT - (n = 2545) significantly reduced the incidence of MACE (OR: 0.56, 95% CI: - 0.47-0.68, P < 0.00001), TLR (OR: 0.51, 95% CI: 0.34-0.75, P = 0.0006) and TVR - (OR: 0.59, 95% CI: 0.46-0.75, P < 0.0001), and did not change significantly in - death (OR: 0.68, 95% CI: 0.44-1.05, P = 0.08), MI (OR: 0.80, 95% CI: 0.45-1.44, - P = 0.46), stent thrombosis (OR: 0.61, 95% CI: 0.27-1.36, P = 0.23), major - bleeding (OR: 1.42, 95% CI: 0.52-3.85, P = 0.49) and overall bleeding (OR: 1.16, - 95% CI: 0.79-1.69, P = 0.45). Compared with prasugrel (n = 6813) or ticagrelor - based DAT (n = 6732), TAT (n = 2545) further reduced the incidence of MACE (OR: - 0.80, 95% CI: 0.72-0.90, P = 0.0012; OR: 0.83, 95% CI: 0.75-0.92, P = 0.0003, - respectively). CONCLUSIONS: Compared with standard DAT, the long-term use of TAT - in patients with PCI gives more benefits in reducing the incidence of MACE, TLR - and TVR without increasing bleeding. Furthermore, it might be superior to - prasugrel or ticagrelor based DAT in term of MACE, which needs to be confirmed by - future studies with direct comparisons. -FAU - Chen, Yu -AU - Chen Y -AD - Division of Cardiology, Xinhua Hospital School of Medicine, Shanghai Jiaotong - University , Shanghai , China. -FAU - Zhang, Yachen -AU - Zhang Y -FAU - Tang, Yong -AU - Tang Y -FAU - Huang, Xiaohong -AU - Huang X -FAU - Xie, Yuquan -AU - Xie Y -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131018 -PL - England -TA - Curr Med Res Opin -JT - Current medical research and opinion -JID - 0351014 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Tetrazoles) -RN - A74586SNO7 (Clopidogrel) -RN - N7Z035406B (Cilostazol) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -CIN - Curr Med Res Opin. 2014 Jan;30(1):51-4. doi: 10.1185/03007995.2013.850070. PMID: - 24089998 -MH - Aspirin/adverse effects/*therapeutic use -MH - Cilostazol -MH - Clopidogrel -MH - Coronary Thrombosis/epidemiology/mortality -MH - Drug Therapy, Combination -MH - Hemorrhage/epidemiology -MH - Humans -MH - Myocardial Infarction/epidemiology/mortality -MH - Percutaneous Coronary Intervention/*methods -MH - Platelet Aggregation Inhibitors/adverse effects/*therapeutic use -MH - Tetrazoles/adverse effects/*therapeutic use -MH - Ticlopidine/adverse effects/*analogs & derivatives/therapeutic use -MH - Treatment Outcome -EDAT- 2013/10/03 06:00 -MHDA- 2014/08/30 06:00 -CRDT- 2013/10/03 06:00 -PHST- 2013/10/03 06:00 [entrez] -PHST- 2013/10/03 06:00 [pubmed] -PHST- 2014/08/30 06:00 [medline] -AID - 10.1185/03007995.2013.850067 [doi] -PST - ppublish -SO - Curr Med Res Opin. 2014 Jan;30(1):37-49. doi: 10.1185/03007995.2013.850067. Epub - 2013 Oct 18. - -PMID- 18628261 -OWN - NLM -STAT- MEDLINE -DCOM- 20090311 -LR - 20250623 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 29 -IP - 21 -DP - 2008 Nov -TI - Clinical outcomes in randomized trials of off- vs. on-pump coronary artery bypass - surgery: systematic review with meta-analyses and trial sequential analyses. -PG - 2601-16 -LID - 10.1093/eurheartj/ehn335 [doi] -AB - AIMS: To assess the clinical outcomes of off- vs. on-pump coronary artery bypass - surgery in randomized trials. METHODS AND RESULTS: We searched electronic - databases and bibliographies until June 2007. Trials were assessed for risk of - bias. Outcome measures were all-cause mortality, myocardial infarction, stroke, - atrial fibrillation, and renewed coronary revascularization at maximum follow-up. - We applied trial sequential analysis to estimate the strength of evidence. We - found 66 randomized trials. There was no statistically significant differences - regarding mortality [relative risk (RR) 0.98; 95% confidence interval (CI) - 0.66-1.44], myocardial infarction (RR 0.95; 95% CI 0.65-1.37), or renewed - coronary revascularization (RR 1.34; 95% CI 0.83-2.18). We found a significant - reduced risk of atrial fibrillation (RR 0.69; 95% CI 0.57-0.83) and stroke (RR - 0.53; 95% CI 0.31-0.91) in off-pump patients. However, when continuity correction - for zero-event trials was included, the reduction in stroke became insignificant - (RR 0.62; 95% CI 0.32-1.19). Trial sequential analysis demonstrated overwhelming - evidence supporting that off-pump bypass surgery reduces atrial fibrillation. - CONCLUSION: Off-pump surgery reduces the risks of postoperative atrial - fibrillation compared with on-pump surgery. For death, myocardial infarction, - stroke, and renewed coronary revascularization, the evidence is still weak and - more low-bias risk trials are needed. -FAU - Møller, Christian H -AU - Møller CH -AD - Department of Cardio-Thoracic Surgery, Rigshospitalet, Copenhagen University - Hospital, Copenhagen, Denmark. chm@ctu.rh.dk -FAU - Penninga, Luit -AU - Penninga L -FAU - Wetterslev, Jørn -AU - Wetterslev J -FAU - Steinbrüchel, Daniel A -AU - Steinbrüchel DA -FAU - Gluud, Christian -AU - Gluud C -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20080715 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -SB - IM -MH - Aged -MH - Atrial Fibrillation/complications/*mortality -MH - Coronary Artery Bypass/adverse effects/methods/*mortality -MH - Coronary Artery Bypass, Off-Pump/adverse effects/mortality -MH - Coronary Stenosis/complications/surgery -MH - Epidemiologic Methods -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/complications/*mortality -MH - Randomized Controlled Trials as Topic -MH - Stroke/complications/*mortality -MH - Treatment Outcome -RF - 140 -EDAT- 2008/07/17 09:00 -MHDA- 2009/03/12 09:00 -CRDT- 2008/07/17 09:00 -PHST- 2008/07/17 09:00 [pubmed] -PHST- 2009/03/12 09:00 [medline] -PHST- 2008/07/17 09:00 [entrez] -AID - ehn335 [pii] -AID - 10.1093/eurheartj/ehn335 [doi] -PST - ppublish -SO - Eur Heart J. 2008 Nov;29(21):2601-16. doi: 10.1093/eurheartj/ehn335. Epub 2008 - Jul 15. - -PMID- 21154257 -OWN - NLM -STAT- MEDLINE -DCOM- 20110325 -LR - 20101214 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 17 -IP - 6 -DP - 2010 -TI - Management of diastolic heart failure. -PG - 558-65 -AB - Diastolic heart failure (HF) is also referred to as HF with preserved left - ventricular systolic function. The distinction between systolic and diastolic HFs - is a pathophysiological one and isolated forms of left ventricular dysfunction - are rarely observed. In diastolic HF left ventricular systolic function is normal - or only slightly impaired, and the typical manifestations of HF result from - increased filling pressure caused by impaired relaxation and compliance of the - left ventricle. The predisposing factors for diastolic dysfunction include - elderly age, female sex, obesity, coronary artery disease, hypertension and - diabetes mellitus. Treatment of diastolic HF is aimed to stop the progression of - the disease, relieve its symptoms, eliminate exacerbations and reduce the - mortality. The management should include antihypertensive treatment, maintenance - of the sinus rhythm, prevention of tachycardia, venous pressure reduction, - prevention of myocardial ischemia and prevention of diabetes mellitus. The - European Society of Cardiology specifies the type of therapy in diastolic HF - based on: angiotensin converting enzyme inhibitors, angiotensin receptor - blockers, beta-blockers, non-dihydropyridine calcium channel blockers, diuretics. - In order to improve the currently poor prognosis in this group of patients the - treatment of diastolic HF must be optimised. -FAU - Kazik, Anna -AU - Kazik A -AD - 3rd Department and Clinical Ward of Cardiology, Poland. ania.kazik@wp.pl -FAU - Wilczek, Krzysztof -AU - Wilczek K -FAU - Poloński, Lech -AU - Poloński L -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Cardiovascular Agents/*therapeutic use -MH - Diastole -MH - Drug Therapy, Combination -MH - Heart Failure, Diastolic/*drug therapy/physiopathology -MH - Humans -MH - Practice Guidelines as Topic -MH - Stroke Volume/drug effects -MH - Systole -MH - Treatment Outcome -MH - Ventricular Dysfunction, Left/*drug therapy/physiopathology -MH - Ventricular Function, Left/*drug effects -EDAT- 2010/12/15 06:00 -MHDA- 2011/03/26 06:00 -CRDT- 2010/12/15 06:00 -PHST- 2010/12/15 06:00 [entrez] -PHST- 2010/12/15 06:00 [pubmed] -PHST- 2011/03/26 06:00 [medline] -PST - ppublish -SO - Cardiol J. 2010;17(6):558-65. - -PMID- 18301872 -OWN - NLM -STAT- MEDLINE -DCOM- 20080715 -LR - 20211020 -IS - 0020-9554 (Print) -IS - 0020-9554 (Linking) -VI - 49 -IP - 4 -DP - 2008 Apr -TI - [Depression in chronic heart failure: complication, risk factor or autonomous - disease?]. -PG - 394, 396-8, 400, 402-4 -LID - 10.1007/s00108-008-2048-5 [doi] -AB - A major depressive episode is diagnosed based on several well-defined criteria as - the presence of depressed mood and loss of interest. According to a large - meta-analysis the prevalence of major depression in patients with chronic heart - failure is more than 20%. Etiological factors include individual (genetic) - disposition and social environment as well as psychosocial stress and biological - risk factors related to the chronic cardiac illness. As in coronary artery - disease, mortality rates are increased in patients suffering from heart failure - and comorbid depression. Possible mechanisms mediating this relationship include - both biological (e.g. severity of chronic heart failure, autonomic and - immunological dysregulation, multiple comorbidities) and behavioral factors - (health behavior, compliance with pharmacological and non-pharmacological - therapy). Shared pathophysiological mechanisms as well as a common genetic - disposition are also discussed. Simple screening instruments and effective - treatment options (psychotherapy, selective serotonin re-uptake inhibitors) are - available. However, at present evidence is lacking that beyond improvement of - depression these strategies impact favorably on morbidity and mortality. -FAU - Faller, H -AU - Faller H -AD - Institut für Psychotherapie und Medizinische Psychologie, Universität Würzburg, - Klinikstrasse 3, 97070, Würzburg, Germany. h.faller@uni-wuerzburg.de -FAU - Angermann, C E -AU - Angermann CE -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Depression bei Herzinsuffizienz: Komplikation, Risikofaktor oder eigene - Erkrankung? -PL - Germany -TA - Internist (Berl) -JT - Der Internist -JID - 0264620 -SB - IM -MH - Comorbidity -MH - Depressive Disorder, Major/*diagnosis/etiology/mortality/therapy -MH - Heart Failure/complications/mortality/*psychology -MH - Humans -MH - Myocardial Infarction/complications/mortality/psychology -MH - Prognosis -MH - Quality of Life/psychology -MH - Survival Rate -RF - 40 -EDAT- 2008/02/28 09:00 -MHDA- 2008/07/17 09:00 -CRDT- 2008/02/28 09:00 -PHST- 2008/02/28 09:00 [pubmed] -PHST- 2008/07/17 09:00 [medline] -PHST- 2008/02/28 09:00 [entrez] -AID - 10.1007/s00108-008-2048-5 [doi] -PST - ppublish -SO - Internist (Berl). 2008 Apr;49(4):394, 396-8, 400, 402-4. doi: - 10.1007/s00108-008-2048-5. - -PMID- 22488701 -OWN - NLM -STAT- MEDLINE -DCOM- 20120530 -LR - 20220321 -IS - 1097-0142 (Electronic) -IS - 0008-543X (Linking) -VI - 118 -IP - 8 Suppl -DP - 2012 Apr 15 -TI - Prospective surveillance and management of cardiac toxicity and health in breast - cancer survivors. -PG - 2270-6 -LID - 10.1002/cncr.27462 [doi] -AB - Breast cancer is commonly diagnosed in postmenopausal women, the majority of whom - express 1 or more cardiovascular disease risk factors. Cardiovascular disease - poses a significant competing risk for morbidity and mortality among - nonmetastatic breast cancer survivors. Adjuvant systemic therapies may result in - late-cardiac toxicity decades after treatment completion. The cumulative - incidence of treatment-related cardiotoxic outcomes may be as high as 33% after - some adjuvant breast cancer therapies. Breast cancer treatment-induced - cardiotoxicity may manifest as cardiomyopathy, coronary ischemia, - thromboembolism, arrhythmias and conduction abnormalities, and valvular and - pericardial disease. Evidence indicates that preexisting cardiovascular - conditions such as hypertension or left ventricular dysfunction may compound the - adverse effects of cardiotoxic treatments. There are currently no published - clinical practice guidelines that address ongoing cardiac surveillance for - cardiotoxicity after breast cancer, and existing guidelines for monitoring and - promoting cardiovascular health in older women are often not followed. The - multidisciplinary prospective surveillance system proposed elsewhere in this - supplement would allow for earlier detection of cardiotoxicity from treatment and - may improve monitoring of cardiovascular health in the growing population of - breast cancer survivors. -CI - Copyright © 2012 American Cancer Society. -FAU - Schmitz, Kathryn H -AU - Schmitz KH -AD - Abramson Cancer Center, Division of Clinical Epidemiology, University of - Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA. - schmitz@mail.med.upenn.edu -FAU - Prosnitz, Robert G -AU - Prosnitz RG -FAU - Schwartz, Anna L -AU - Schwartz AL -FAU - Carver, Joseph R -AU - Carver JR -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cancer -JT - Cancer -JID - 0374236 -RN - 0 (Antineoplastic Agents) -SB - IM -MH - Adult -MH - Aged -MH - American Cancer Society -MH - Antineoplastic Agents/*adverse effects -MH - Breast Neoplasms/epidemiology/*therapy -MH - Cardiovascular Diseases/epidemiology/prevention & control/*therapy -MH - Chemotherapy, Adjuvant -MH - Combined Modality Therapy -MH - Congresses as Topic -MH - Female -MH - Heart/*drug effects/*radiation effects -MH - Humans -MH - Incidence -MH - Longitudinal Studies -MH - Middle Aged -MH - Practice Guidelines as Topic -MH - Primary Prevention/methods -MH - Prognosis -MH - Prospective Studies -MH - Radiotherapy, Adjuvant -MH - Risk Assessment -MH - Severity of Illness Index -MH - Survivors -MH - Treatment Outcome -MH - *Women's Health -EDAT- 2012/04/18 06:00 -MHDA- 2012/05/31 06:00 -CRDT- 2012/04/11 06:00 -PHST- 2012/04/11 06:00 [entrez] -PHST- 2012/04/18 06:00 [pubmed] -PHST- 2012/05/31 06:00 [medline] -AID - 10.1002/cncr.27462 [doi] -PST - ppublish -SO - Cancer. 2012 Apr 15;118(8 Suppl):2270-6. doi: 10.1002/cncr.27462. - -PMID- 22365161 -OWN - NLM -STAT- MEDLINE -DCOM- 20120614 -LR - 20120227 -IS - 1558-4488 (Electronic) -IS - 0270-9295 (Linking) -VI - 32 -IP - 1 -DP - 2012 Jan -TI - Cardio-renal syndrome type 4: epidemiology, pathophysiology and treatment. -PG - 40-8 -LID - 10.1016/j.semnephrol.2011.11.006 [doi] -AB - Cardiovascular diseases such as coronary artery disease, congestive heart - failure, arrhythmia, and sudden cardiac death represent the leading causes of - morbidity and mortality in patients with CKD, increasing sharply as patients - approach end-stage renal disease. The pathogenesis includes a complex, - bidirectional interaction between the heart and kidneys that encompasses - traditional and nontraditional risk factors, and has been termed cardio-renal - syndrome type 4. In this review, an overview of the epidemiology and scope of - this problem is provided, some suggested mechanisms for the pathophysiology of - this disorder are discussed, and some of the key treatment strategies are - described, with particular focus on recent clinical trials, both negative and - positive. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - House, Andrew A -AU - House AA -AD - Schulich School of Medicine and Dentistry, University of Western Ontario Division - of Nephrology, University Hospital, London, Ontario, Canada. - andrew.house@lhsc.on.ca -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Semin Nephrol -JT - Seminars in nephrology -JID - 8110298 -RN - 0 (Hematinics) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Vitamins) -SB - IM -MH - *Cardio-Renal Syndrome/epidemiology/physiopathology/therapy -MH - Heart Failure/epidemiology/*etiology/physiopathology/therapy -MH - Hematinics/therapeutic use -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Kidney Failure, Chronic/*complications/epidemiology/physiopathology/therapy -MH - Renal Dialysis -MH - Renal Insufficiency, Chronic/*complications/epidemiology/physiopathology/therapy -MH - Vitamins/therapeutic use -EDAT- 2012/03/01 06:00 -MHDA- 2012/06/15 06:00 -CRDT- 2012/02/28 06:00 -PHST- 2012/02/28 06:00 [entrez] -PHST- 2012/03/01 06:00 [pubmed] -PHST- 2012/06/15 06:00 [medline] -AID - S0270-9295(11)00185-9 [pii] -AID - 10.1016/j.semnephrol.2011.11.006 [doi] -PST - ppublish -SO - Semin Nephrol. 2012 Jan;32(1):40-8. doi: 10.1016/j.semnephrol.2011.11.006. - -PMID- 22882412 -OWN - NLM -STAT- MEDLINE -DCOM- 20130307 -LR - 20161125 -IS - 1540-8191 (Electronic) -IS - 0886-0440 (Linking) -VI - 27 -IP - 5 -DP - 2012 Sep -TI - Management of recurrent leaks following postinfarction ventricular septal defect - repairs. -PG - 576-80 -LID - 10.1111/j.1540-8191.2012.01493.x [doi] -AB - Ventricular septal rupture (VSR) complicates acute myocardial infarction (AMI) in - less than 0.2% of cases and is usually surgically managed by endocardial patch - repair with infarct exclusion. Although successful in 80% of cases, failure of - patch repair (often because of patch dehiscence) results in attempts at - percutaneous closure as reoperative mortality can be as high as 40%. We describe - a case of an AMI in a 63-year-old male with resultant VSR that required repeat - surgical patch repair secondary to recurrent leak. We discuss the management of - recurrent leaks and surgical techniques aimed at decreasing residual defects. -CI - © 2012 Wiley Periodicals, Inc. -FAU - Sayfo, Sameh -AU - Sayfo S -AD - Division of Cardiovascular Medicine, University of Louisville of School of - Medicine, Louisville, Kentucky 40202, USA. -FAU - Stepp, Lindsay O -AU - Stepp LO -FAU - Ganzel, Brian -AU - Ganzel B -FAU - Slaughter, Mark S -AU - Slaughter MS -FAU - Flaherty, Michael P -AU - Flaherty MP -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20120813 -PL - United States -TA - J Card Surg -JT - Journal of cardiac surgery -JID - 8908809 -SB - IM -MH - Anastomotic Leak/diagnostic imaging/*surgery -MH - Cardiac Surgical Procedures/*methods -MH - Coronary Angiography/methods -MH - Coronary Artery Bypass/adverse effects/*methods -MH - Coronary Stenosis/complications/diagnostic imaging -MH - Echocardiography, Transesophageal/methods -MH - Follow-Up Studies -MH - Heart Rupture, Post-Infarction/diagnostic imaging/surgery -MH - Humans -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/complications/diagnostic imaging/*surgery -MH - Postoperative Complications/diagnostic imaging/surgery -MH - Rare Diseases -MH - Risk Assessment -MH - Severity of Illness Index -MH - Treatment Outcome -MH - Ventricular Septal Rupture/*diagnostic imaging/*surgery -EDAT- 2012/08/14 06:00 -MHDA- 2013/03/08 06:00 -CRDT- 2012/08/14 06:00 -PHST- 2012/08/14 06:00 [entrez] -PHST- 2012/08/14 06:00 [pubmed] -PHST- 2013/03/08 06:00 [medline] -AID - 10.1111/j.1540-8191.2012.01493.x [doi] -PST - ppublish -SO - J Card Surg. 2012 Sep;27(5):576-80. doi: 10.1111/j.1540-8191.2012.01493.x. Epub - 2012 Aug 13. - -PMID- 21087567 -OWN - NLM -STAT- MEDLINE -DCOM- 20110406 -LR - 20101122 -IS - 1467-1107 (Electronic) -IS - 1047-9511 (Linking) -VI - 20 Suppl 3 -DP - 2010 Dec -TI - Rare problems associated with the Fontan circulation. -PG - 113-9 -LID - 10.1017/S1047951110001162 [doi] -AB - The Fontan operation, originally described for the surgical management of - tricuspid atresia, is now the final surgery in the strategy of staged palliation - for a number of different forms of congenital cardiac disease with a functionally - univentricular heart. Despite the improved technical outcomes of the Fontan - operation, staged palliation does not recreate a normal physiology. Without a - pumping chamber delivering blood to the lungs, the cardiovascular system is less - efficient; cardiac output is generally diminished, and the systemic venous - pressure is increased. As a result, patients with "Fontan physiology" may face a - number of rare but potentially life-threatening complications including hepatic - dysfunction, abnormalities of coagulation, protein-losing enteropathy, and - plastic bronchitis. Despite the staged palliation resulting in remarkable - survival, the possible complications for this group of patients are complex, - involve multiple organ systems, and can be life threatening. Identifying the - mechanisms associated with each of the rare complications, and developing - strategies to treat them, requires the work of many people at many institutions. - Continued collaboration between sub-specialists and between institutions will be - required to optimise the care for this group of survivors with functionally - univentricular hearts. -FAU - Goldberg, David J -AU - Goldberg DJ -AD - Division of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, - Pennsylvania 19104, United States of America. goldbergda@email.chop.edu -FAU - Dodds, Kathryn -AU - Dodds K -FAU - Rychik, Jack -AU - Rychik J -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Cardiol Young -JT - Cardiology in the young -JID - 9200019 -SB - IM -MH - Blood Coagulation Disorders/etiology -MH - Bronchitis/etiology -MH - Child -MH - Coronary Circulation -MH - Fontan Procedure/*adverse effects -MH - Heart Defects, Congenital/*physiopathology/*surgery -MH - Humans -MH - Protein-Losing Enteropathies/etiology -EDAT- 2010/11/23 06:00 -MHDA- 2011/04/07 06:00 -CRDT- 2010/11/20 06:00 -PHST- 2010/11/20 06:00 [entrez] -PHST- 2010/11/23 06:00 [pubmed] -PHST- 2011/04/07 06:00 [medline] -AID - S1047951110001162 [pii] -AID - 10.1017/S1047951110001162 [doi] -PST - ppublish -SO - Cardiol Young. 2010 Dec;20 Suppl 3:113-9. doi: 10.1017/S1047951110001162. - -PMID- 21854888 -OWN - NLM -STAT- MEDLINE -DCOM- 20111024 -LR - 20171116 -IS - 1555-7162 (Electronic) -IS - 0002-9343 (Linking) -VI - 124 -IP - 9 -DP - 2011 Sep -TI - Cardiac resynchronization therapy: what? Who? When? How? -PG - 813-5 -LID - 10.1016/j.amjmed.2010.09.028 [doi] -AB - Cardiac resynchronization therapy is an important and underused tool to help - patients with heart failure symptoms, left ventricular systolic dysfunction - (LVEF≤35%), and intraventricular conduction system disease (QRS≥120 msec). - Cardiac resynchronization therapy paces the heart simultaneously from both right - and left ventricles (through the coronary sinus). Approximately three quarters of - patients who undergo a successful implant will have some degree of symptomatic - improvement and have fewer heart failure hospitalizations. When cardiac - resynchronization therapy is combined with a defibrillator, patients may benefit - from the added protection against sudden arrhythmic death. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Cuculich, Phillip S -AU - Cuculich PS -AD - Cardiac Electrophysiology, Division of Cardiovascular Diseases, Washington - University School of Medicine, St Louis, MO 63110, USA. pcuculic@wustl.edu -FAU - Joseph, Susan -AU - Joseph S -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Med -JT - The American journal of medicine -JID - 0267200 -SB - IM -MH - Arrhythmias, Cardiac/physiopathology/*therapy -MH - Cardiac Output, Low/*therapy -MH - Cardiac Resynchronization Therapy/*methods -MH - Combined Modality Therapy -MH - Contraindications -MH - Death, Sudden, Cardiac/prevention & control -MH - Defibrillators, Implantable -MH - Heart Failure/physiopathology/*therapy -MH - Heart Ventricles/physiopathology -MH - Humans -MH - Monitoring, Ambulatory/instrumentation -MH - Myocardial Ischemia/complications/therapy -MH - Remote Sensing Technology/instrumentation -MH - Ventricular Dysfunction, Left/physiopathology/*therapy -EDAT- 2011/08/23 06:00 -MHDA- 2011/10/25 06:00 -CRDT- 2011/08/23 06:00 -PHST- 2010/07/15 00:00 [received] -PHST- 2010/08/30 00:00 [revised] -PHST- 2010/09/01 00:00 [accepted] -PHST- 2011/08/23 06:00 [entrez] -PHST- 2011/08/23 06:00 [pubmed] -PHST- 2011/10/25 06:00 [medline] -AID - S0002-9343(11)00409-8 [pii] -AID - 10.1016/j.amjmed.2010.09.028 [doi] -PST - ppublish -SO - Am J Med. 2011 Sep;124(9):813-5. doi: 10.1016/j.amjmed.2010.09.028. - -PMID- 19553809 -OWN - NLM -STAT- MEDLINE -DCOM- 20091104 -LR - 20090722 -IS - 1531-7072 (Electronic) -IS - 1070-5295 (Linking) -VI - 15 -IP - 4 -DP - 2009 Aug -TI - Cardiovascular problems in noncardiac surgery. -PG - 333-41 -LID - 10.1097/MCC.0b013e32832e4795 [doi] -AB - PURPOSE OF REVIEW: Perioperative cardiac complications remain a major area of - concern as our surgical population increases in volume, age and frequency of - comorbidity. A variety of strategies can be used to optimize patients and - potentially reduce the incidence of these serious complications. RECENT FINDINGS: - Recent literature suggests a trend towards less invasive testing for detection - and quantification of coronary artery disease and greater interest in - pharmacologic 'cardioprotection' using beta-blockers, statins and other agents - targeting heart rate control and other mechanisms (e.g. reducing inflammatory - responses). The recent Perioperative Ischemic Evaluation study has substantially - altered this approach at least towards widespread application to - lower/intermediate risk cohorts. Considerable attention has been focused on - ensuring optimal standardized perioperative management of patients with a recent - percutaneous coronary intervention, particularly those with an intracoronary - stent. Widespread surveillance of postoperative troponin release and increasing - recognition of the prognostic potential of elevated preoperative brain - natriuretic peptides point towards changing strategies for long-term risk - stratification. SUMMARY: The complexity of a particular patient's physiologic - responses to a wide variety of surgical procedures, which are undergoing constant - technological refinement generally associated with lesser degrees of invasivity - and stress make calculation of patients' perioperative risk very challenging. At - the present time, adequate information is available for the clinician to screen - patients with high-risk preoperative predictors, delay elective surgery for - patients with recent intracoronary stents and continue chronic beta-blockade in - appropriate patients. New large-scale database and subanalyses of major trials - (e.g. Perioperative Ischemic Evaluation and Coronary Artery Revascularization - Prophylaxis) should provide additional information to minimize perioperative - cardiac risk. -FAU - London, Martin J -AU - London MJ -AD - Department of Anesthesia and Perioperative Care, University of California and San - Francisco Veterans Affairs Medical Center, San Francisco, California, USA. - londonm@anesthesia.ucsf.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Crit Care -JT - Current opinion in critical care -JID - 9504454 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Natriuretic Peptides) -RN - 0 (Troponin) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Cardiovascular System/*injuries -MH - Humans -MH - Natriuretic Peptide, Brain/blood -MH - Natriuretic Peptides/blood -MH - Postoperative Complications/drug therapy/*prevention & control -MH - Troponin/biosynthesis -RF - 61 -EDAT- 2009/06/26 09:00 -MHDA- 2009/11/05 06:00 -CRDT- 2009/06/26 09:00 -PHST- 2009/06/26 09:00 [entrez] -PHST- 2009/06/26 09:00 [pubmed] -PHST- 2009/11/05 06:00 [medline] -AID - 10.1097/MCC.0b013e32832e4795 [doi] -PST - ppublish -SO - Curr Opin Crit Care. 2009 Aug;15(4):333-41. doi: 10.1097/MCC.0b013e32832e4795. - -PMID- 18303934 -OWN - NLM -STAT- MEDLINE -DCOM- 20080708 -LR - 20181025 -IS - 1175-3277 (Print) -IS - 1175-3277 (Linking) -VI - 8 -IP - 1 -DP - 2008 -TI - Low-molecular-weight heparins : mechanisms, trials, and role in contemporary - interventional medicine. -PG - 15-25 -AB - The clinical spectrum of acute coronary syndromes (ACS) encompasses unstable - angina, non-ST-elevation, and ST-elevation myocardial infarction (STEMI). Within - an atherosclerotic plaque, disruption of the endothelium can lead to exposure of - tissue factor, with platelet adhesion, activation and aggregation, along with - activation of the coagulation cascade, culminating in thrombin formation and the - development of a cross-linked fibrin clot at the site of injury. Therapy aimed at - blocking thrombin formation is now an integral part of the current cardiovascular - guidelines in the treatment of ACS. Although unfractionated heparin (UFH) has - been the mainstay of antithrombin therapy in the past, it has numerous clinical - and biochemical limitations, including substantial protein binding (leading to - inconsistent bioavailability), a need for frequent monitoring and adjustment, - unreliable and variable degrees of anticoagulation, significant platelet - activation, risk of heparin-induced thrombocytopenia, and the inability to block - clot bound thrombin. With all of these limitations of UFH, low-molecular-weight - heparins (LMWHs) have emerged as attractive alternatives. This review discusses - the mechanism of action of LMWHs, and summarizes available literature concerning - the use of LMWHs in a variety of clinical settings. Included in this review is an - analysis of both current and prior data showing LMWH is as effective as UFH in - the conservative and invasive management of patients with ACS. As well, very - recent data are evaluated showing the safety and efficacy of LMWHs used in - patients transitioning to the cardiac catheterization laboratory, and in those - patients undergoing elective or urgent percutaneous coronary intervention (PCI). - We also appraise the literature, along with the very recent studies investigating - the use of LMWHs as adjunctive therapy to fibrinolytics in patients with STEMI. - Finally, we set forth real-world conclusions concerning the use of LMWHs in - contemporary interventional practice, including elective PCI and the treatment of - ischemic coronary artery disease in the context of rapid invasive management of - ACS. -FAU - Canales, John F -AU - Canales JF -AD - Department of Cardiology Research, Texas Heart Institute at St Luke's Episcopal - Hospital, Baylor College of Medicine, The University of Texas Health Science - Center at Houston, Houston, Texas 77225-0269, USA. -FAU - Ferguson, James J -AU - Ferguson JJ -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -RN - 0 (Anticoagulants) -RN - 0 (Heparin, Low-Molecular-Weight) -SB - IM -MH - Acute Coronary Syndrome/*drug therapy -MH - Angioplasty, Balloon, Coronary -MH - Anticoagulants/pharmacology/*therapeutic use -MH - Heparin, Low-Molecular-Weight/pharmacology/*therapeutic use -MH - Humans -MH - Myocardial Infarction/drug therapy -RF - 51 -EDAT- 2008/02/29 09:00 -MHDA- 2008/07/09 09:00 -CRDT- 2008/02/29 09:00 -PHST- 2008/02/29 09:00 [pubmed] -PHST- 2008/07/09 09:00 [medline] -PHST- 2008/02/29 09:00 [entrez] -AID - 813 [pii] -AID - 10.2165/00129784-200808010-00003 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2008;8(1):15-25. doi: 10.2165/00129784-200808010-00003. - -PMID- 16431176 -OWN - NLM -STAT- MEDLINE -DCOM- 20060306 -LR - 20250623 -IS - 1555-7162 (Electronic) -IS - 0002-9343 (Linking) -VI - 119 -IP - 1 -DP - 2006 Jan -TI - Transient left ventricular dysfunction under severe stress: brain-heart - relationship revisited. -PG - 10-7 -AB - PURPOSE: Transient left ventricular dysfunction in patients under emotional or - physical stress, also known as tako-tsubo-like left ventricular dysfunction, has - been recently been recognized as a distinct clinical entity. The aims of this - review are to define this phenomenon and to explore its similarities to the left - ventricular dysfunction seen in patients with acute brain injury. METHODS: - MEDLINE database, bibliographies of each citation for relevant articles, and - consultation with clinical experts were used to examine the clinical picture of - tako-tsubo-like left ventricular dysfunction. RESULTS: We identified case series - and a systematic review that report on patients with this syndrome. This - phenomenon occurs predominantly in female patients, presenting with a variety of - ST-T segment changes and mildly elevated cardiac enzymes that mimic an acute - coronary syndrome. The left ventricular dysfunction, typically showing a - hyperkinetic basal region and an akinetic apical half of the ventricle, occurs in - the absence of obstructed epicardial coronary arteries. The ventricular - dysfunction usually resolves within weeks with a generally favorable prognosis. - This phenomenon has similarities to that seen in patients with acute brain injury - with regard to clinical presentation, pathology, and its reversible nature. - CONCLUSIONS: Transient left ventricular dysfunction occurs in the absence of - obstructive epicardial coronary artery disease. In its broadest sense, this - phenomenon may encompass a range of disorders including left ventricular - dysfunction after central nervous system injury. -FAU - Ako, Junya -AU - Ako J -AD - The Center for Research in Cardiovascular Interventions, Stanford University - Medical Center, Stanford, Calif 94305-5637, USA. -FAU - Sudhir, Krishnankutty -AU - Sudhir K -FAU - Farouque, H M Omar -AU - Farouque HM -FAU - Honda, Yasuhiro -AU - Honda Y -FAU - Fitzgerald, Peter J -AU - Fitzgerald PJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - United States -TA - Am J Med -JT - The American journal of medicine -JID - 0267200 -SB - IM -MH - Electrocardiography -MH - Female -MH - Humans -MH - Stress, Physiological/*complications -MH - Stress, Psychological/*complications -MH - Sympathetic Nervous System/physiopathology -MH - Syndrome -MH - Ventricular Dysfunction, Left/diagnosis/*etiology/physiopathology/therapy -RF - 52 -EDAT- 2006/01/25 09:00 -MHDA- 2006/03/07 09:00 -CRDT- 2006/01/25 09:00 -PHST- 2005/01/27 00:00 [received] -PHST- 2005/08/12 00:00 [accepted] -PHST- 2006/01/25 09:00 [pubmed] -PHST- 2006/03/07 09:00 [medline] -PHST- 2006/01/25 09:00 [entrez] -AID - S0002-9343(05)00754-0 [pii] -AID - 10.1016/j.amjmed.2005.08.022 [doi] -PST - ppublish -SO - Am J Med. 2006 Jan;119(1):10-7. doi: 10.1016/j.amjmed.2005.08.022. - -PMID- 17545824 -OWN - NLM -STAT- MEDLINE -DCOM- 20070710 -LR - 20070604 -IS - 1550-5049 (Electronic) -IS - 0889-4655 (Linking) -VI - 22 -IP - 3 -DP - 2007 May-Jun -TI - Cardiovascular risk reduction in high-risk pediatric patients: a scientific - statement from the American Heart Association Expert Panel on Population and - Prevention Science; the Councils on Cardiovascular Disease in the Young, - Epidemiology and Prevention, Nutrition, Physical Activity and Metabolism, High - Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; - and the Interdisciplinary Working Group on Quality of Care and Outcomes Research. -PG - 218-53 -AB - Although for most children the process of atherosclerosis is subclinical, - dramatically accelerated atherosclerosis occurs in some pediatric disease states, - with clinical coronary events occurring in childhood and very early adult life. - As with most scientific statements about children and the future risk for - cardiovascular disease, there are no randomized trials documenting the effects of - risk reduction on hard clinical outcomes. A growing body of literature, however, - identifies the importance of premature cardiovascular disease in the course of - certain pediatric diagnoses and addresses the response to risk factor reduction. - For this scientific statement, a panel of experts reviewed what is known about - very premature cardiovascular disease in 8 high-risk pediatric diagnoses and, - from the science base, developed practical recommendations for management of - cardiovascular risk. -FAU - Kavey, Rae-Ellen W -AU - Kavey RE -FAU - Allada, Vivek -AU - Allada V -FAU - Daniels, Stephen R -AU - Daniels SR -FAU - Hayman, Laura L -AU - Hayman LL -FAU - McCrindle, Brian W -AU - McCrindle BW -FAU - Newburger, Jane W -AU - Newburger JW -FAU - Parekh, Rulan S -AU - Parekh RS -FAU - Steinberger, Julia -AU - Steinberger J -CN - American Heart Association Expert Panel on Population and Prevention Science -CN - Council on Cardiovascular Disease in the Young -CN - Council on Epidemiology and Prevention -CN - Council on Nutrition -CN - Council on Physical Activity and Metabolism -CN - Council on High Blood Pressure Research -CN - Council on Cardiovascular Nursing -CN - Council on the Kidney in Heart Disease -CN - Interdisciplinary Working Group on Quality of Care and Outcomes Research -LA - eng -PT - Consensus Development Conference -PT - Journal Article -PT - Practice Guideline -PL - United States -TA - J Cardiovasc Nurs -JT - The Journal of cardiovascular nursing -JID - 8703516 -SB - IM -MH - Age of Onset -MH - Atherosclerosis/*complications/*prevention & control -MH - Cardiovascular Diseases/*prevention & control -MH - Child -MH - Diabetes Complications/prevention & control -MH - Diabetes Mellitus/genetics -MH - Heart Diseases/congenital -MH - Heart Transplantation -MH - Humans -MH - Hypercholesterolemia/complications/genetics/prevention & control -MH - Inflammation -MH - Kidney Diseases/complications/prevention & control -MH - Mucocutaneous Lymph Node Syndrome/complications -MH - Neoplasms/complications -MH - *Pediatrics -MH - Risk Factors -MH - *Risk Reduction Behavior -MH - Survivors -RF - 401 -EDAT- 2007/06/05 09:00 -MHDA- 2007/07/11 09:00 -CRDT- 2007/06/05 09:00 -PHST- 2007/06/05 09:00 [pubmed] -PHST- 2007/07/11 09:00 [medline] -PHST- 2007/06/05 09:00 [entrez] -AID - 00005082-200705000-00008 [pii] -AID - 10.1097/01.JCN.0000267827.50320.85 [doi] -PST - ppublish -SO - J Cardiovasc Nurs. 2007 May-Jun;22(3):218-53. doi: - 10.1097/01.JCN.0000267827.50320.85. - -PMID- 22170292 -OWN - NLM -STAT- MEDLINE -DCOM- 20120503 -LR - 20181201 -IS - 1865-8652 (Electronic) -IS - 0741-238X (Linking) -VI - 28 -IP - 12 -DP - 2011 Dec -TI - The management of patients with atrial fibrillation and dronedarone's place in - therapy. -PG - 1059-77 -LID - 10.1007/s12325-011-0086-1 [doi] -AB - The pharmacologic management of atrial fibrillation (AF) includes rate and rhythm - control strategies. Antiarrhythmic agents (eg, amiodarone, flecainide, and - propafenone) are limited by serious toxicities (including proarrhythmic effects - and pulmonary toxicity), which may lead to a reduced net clinical efficacy of - rhythm control strategies. Dronedarone, a new antiarrhythmic agent, is effective - in the maintenance of sinus rhythm. Dronedarone has also been shown to reduce - ventricular rate and the incidence of hospitalization due to cardiovascular - events. Dronedarone is recommended by the 2011 American College of Cardiology - Foundation/American Heart Association/Heart Rhythm Society guidelines update for - the management of AF patients with no or minimal heart disease, coronary artery - disease, and hypertension with no left ventricular hypertrophy. Dronedarone is - contraindicated in patients with New York Heart Association (NYHA) class IV heart - failure or NYHA class II-III heart failure with a recent decompensation requiring - hospitalization or referral to a specialized heart failure clinic. -FAU - Cohen, Marc -AU - Cohen M -AD - Cardiac Cath Laboratory, Newark Beth Israel Medical Center, NJ 07112, USA. - marcohen@barnabashealth.org -FAU - Boiangiu, Catalin -AU - Boiangiu C -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20111212 -PL - United States -TA - Adv Ther -JT - Advances in therapy -JID - 8611864 -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Anticoagulants) -RN - JQZ1L091Y2 (Dronedarone) -RN - N3RQ532IUT (Amiodarone) -MH - Age Factors -MH - Amiodarone/administration & dosage/adverse effects/*analogs & - derivatives/therapeutic use -MH - Anti-Arrhythmia Agents/administration & dosage/adverse effects/*therapeutic use -MH - Anticoagulants/therapeutic use -MH - Atrial Fibrillation/complications/*drug therapy/*physiopathology -MH - Cardiovascular Diseases/complications -MH - Clinical Trials as Topic -MH - Dronedarone -MH - Heart Rate/drug effects -MH - Humans -MH - Practice Guidelines as Topic -MH - Risk Factors -MH - Sex Factors -EDAT- 2011/12/16 06:00 -MHDA- 2012/05/04 06:00 -CRDT- 2011/12/16 06:00 -PHST- 2011/09/22 00:00 [received] -PHST- 2011/12/16 06:00 [entrez] -PHST- 2011/12/16 06:00 [pubmed] -PHST- 2012/05/04 06:00 [medline] -AID - 10.1007/s12325-011-0086-1 [doi] -PST - ppublish -SO - Adv Ther. 2011 Dec;28(12):1059-77. doi: 10.1007/s12325-011-0086-1. Epub 2011 Dec - 12. - -PMID- 18777453 -OWN - NLM -STAT- MEDLINE -DCOM- 20081205 -LR - 20080908 -IS - 0947-7349 (Print) -IS - 0947-7349 (Linking) -VI - 116 Suppl 1 -DP - 2008 Sep -TI - Sweet heart - contributions of metabolism in the development of heart failure in - diabetes mellitus. -PG - S40-5 -LID - 10.1055/s-2008-1081496 [doi] -AB - With the rapidly increasing prevalence of type 2 diabetes mellitus the risk for - cardiovascular events is increasing. Almost 2 of 3 patients who present with - symptomatic CHD have abnormal glucose homeostasis. Patients with diabetes - mellitus and cardiovascular disease have an unfavourable prognosis. The most - important result of diabetes metabolism is the switch from carbohydrates and - fatty acids as a source of energy to an excessive use of fatty acids. The adverse - influence of diabetes mellitus extends to all components of the cardiovascular - system, including microvasculature, the epicardial coronary arteries, the large - conduit arteries and the heart, as well as the kidneys. Focus of this review is - the myocardial metabolism in heart failure and diabetes mellitus. -FAU - Stratmann, B -AU - Stratmann B -AD - Heart and Diabetes Center NRW, Ruhr-University Bochum, Oeynhausen, Germany. -FAU - Tschoepe, D -AU - Tschoepe D -LA - eng -PT - Journal Article -PT - Review -DEP - 20080905 -PL - Germany -TA - Exp Clin Endocrinol Diabetes -JT - Experimental and clinical endocrinology & diabetes : official journal, German - Society of Endocrinology [and] German Diabetes Association -JID - 9505926 -RN - 0 (Blood Glucose) -RN - 0 (Fatty Acids) -SB - IM -MH - Blood Glucose/metabolism -MH - Diabetes Mellitus, Type 2/*complications/*metabolism/physiopathology -MH - Diabetic Angiopathies/etiology/*metabolism -MH - Energy Metabolism/physiology -MH - Fatty Acids/metabolism -MH - Heart Failure/*etiology/*metabolism -MH - Humans -MH - Insulin Resistance/physiology -RF - 75 -EDAT- 2008/10/23 09:00 -MHDA- 2008/12/17 09:00 -CRDT- 2008/10/23 09:00 -PHST- 2008/10/23 09:00 [pubmed] -PHST- 2008/12/17 09:00 [medline] -PHST- 2008/10/23 09:00 [entrez] -AID - 10.1055/s-2008-1081496 [doi] -PST - ppublish -SO - Exp Clin Endocrinol Diabetes. 2008 Sep;116 Suppl 1:S40-5. doi: - 10.1055/s-2008-1081496. Epub 2008 Sep 5. - -PMID- 17659159 -OWN - NLM -STAT- MEDLINE -DCOM- 20071017 -LR - 20190911 -IS - 1473-4877 (Electronic) -IS - 0300-7995 (Linking) -VI - 23 -IP - 8 -DP - 2007 Aug -TI - Meta-analysis of the cholesterol-lowering effect of ezetimibe added to ongoing - statin therapy. -PG - 2009-26 -AB - OBJECTIVE: To review and analyse the evidence for the cholesterol-lowering effect - of ezetimibe in adult patients with hypercholesterolaemia who are not at - low-density lipoprotein cholesterol (LDL-C) goal on statin monotherapy. RESEARCH - DESIGN: Systematic review and meta-analysis. METHODS: MEDLINE and EMBASE were - searched to identify ezetimibe randomised controlled trials (RCTs) published - between January 1993 and December 2005. The meta-analysis combined data from - RCTs, with a minimum treatment duration of 6 weeks, that compared treatment with - ezetimibe 10 mg/day or placebo added to current statin therapy. The difference - between treatments was analysed for four co-primary outcomes: mean percentage - change from baseline in total cholesterol (TC), LDL-C, and high-density - lipoprotein cholesterol (HDL-C), and number of patients achieving LDL-C treatment - goal. Meta-analysis results are presented for a modified version of the inverse - variance random effects model. RESULTS: Five RCTs involving a total of 5039 - patients were included in the meta-analysis. The weighted mean difference (WMD) - between treatments significantly favoured the ezetimibe/statin combination over - placebo/statin for TC (-16.1% (-17.3, -14.8); p < 0.0001), LDL-C (-23.6% (-25.6, - -21.7); p < 0.0001) and HDL-C (1.7% (0.9, 2.5); p < 0.0001). The relative risk of - reaching the LDL-C treatment goal was significantly higher for patients on - ezetimibe/statin relative to those on placebo/statin (3.4 (2.0, 5.6); p < - 0.0001). In pre-defined sub-group analyses of studies in patients with coronary - heart disease, the WMD between treatments remained significantly in favour of - ezetimibe/statin (p < 0.0001) for TC and LDL-C but was no longer significant for - HDL-C. Elevations in creatine kinase, alanine aminotransferase or aspartate - aminotransferase that were considered as an adverse effect did not differ - significantly between treatments. CONCLUSIONS: The meta-analysis we performed - included only five studies and was restricted to analysis of the changes in - cholesterol levels relative to baseline. However, the results suggest that - ezetimibe co-administered with ongoing statin therapy provides significant - additional lipid-lowering in patients not at LDL-C goal on statin therapy alone, - allowing more patients to reach their LDL-C goal. -FAU - Mikhailidis, D P -AU - Mikhailidis DP -AD - Department of Clinical Biochemistry (Vascular Disease Prevention Clinics), Royal - Free Hospital, Royal Free and University College School of Medicine, London, UK. - MIKHAILIDIS@aol.com -FAU - Sibbring, G C -AU - Sibbring GC -FAU - Ballantyne, C M -AU - Ballantyne CM -FAU - Davies, G M -AU - Davies GM -FAU - Catapano, A L -AU - Catapano AL -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - England -TA - Curr Med Res Opin -JT - Current medical research and opinion -JID - 0351014 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Azetidines) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Lipoproteins) -RN - 0 (Placebos) -RN - 0 (Triglycerides) -RN - 97C5T2UQ7J (Cholesterol) -RN - EOR26LQQ24 (Ezetimibe) -SB - IM -MH - Anticholesteremic Agents/administration & dosage/*therapeutic use -MH - Azetidines/administration & dosage/*therapeutic use -MH - Cholesterol/blood -MH - Ezetimibe -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & - dosage/*therapeutic use -MH - Hypercholesterolemia/*drug therapy -MH - Lipoproteins/blood -MH - Placebos -MH - Randomized Controlled Trials as Topic -MH - Triglycerides/blood -EDAT- 2007/07/31 09:00 -MHDA- 2007/10/18 09:00 -CRDT- 2007/07/31 09:00 -PHST- 2007/07/31 09:00 [pubmed] -PHST- 2007/10/18 09:00 [medline] -PHST- 2007/07/31 09:00 [entrez] -AID - 10.1185/030079907x210507 [doi] -PST - ppublish -SO - Curr Med Res Opin. 2007 Aug;23(8):2009-26. doi: 10.1185/030079907x210507. - -PMID- 18257600 -OWN - NLM -STAT- MEDLINE -DCOM- 20080501 -LR - 20211020 -IS - 1170-229X (Print) -IS - 1170-229X (Linking) -VI - 25 -IP - 2 -DP - 2008 -TI - Use of beta-adrenoceptor antagonists in older patients with chronic obstructive - pulmonary disease and cardiovascular co-morbidity: safety issues. -PG - 131-44 -AB - The incidence of and mortality from both chronic obstructive pulmonary disease - (COPD) and cardiovascular disease (CVD) increase with age. In addition, the - average age of patients with COPD and CVD is also increasing as a result of - improvements in both pharmacological and non-pharmacological treatments. Coronary - artery disease is a compelling indication for beta-adrenoceptor antagonist use in - a population in whom beta-adrenoceptor antagonism is often viewed as - contraindicated. beta-Adrenoceptor antagonists have been proven to improve - cardiovascular morbidity and mortality but have been under-utilized in patients - with COPD with concomitant CVD because of a fear of bronchoconstriction and - adverse effects, particularly in the elderly. The advanced age of patients with - COPD and CVD, along with the sheer number of patients with these diseases, - necessitates that clinicians understand the treatment of these co-morbidities - using seemingly conflicting therapy in the form of beta-adrenoceptor agonists and - antagonists. We review changes in the pharmacokinetics and pharmacodynamics of - beta-adrenoceptor antagonists in the elderly, the role of beta-adrenoceptor - antagonists in CVD and the literature regarding the safety and mortality benefits - of beta-adrenoceptor antagonists in elderly patients with COPD and concomitant - CVD. We conclude that cardioselective beta-adrenoceptor antagonists appear to be - safe to use in elderly male patients with mild-to-moderate COPD who have a - compelling indication for beta-adrenoceptor antagonist therapy. Data in female - patients are very limited. Nonselective beta-adrenoceptor antagonists should be - avoided in general, except in patients with heart failure who might benefit - significantly from the use of carvedilol. beta-Adrenoceptor antagonists have been - shown to improve mortality in older patients with coexisting CVD and COPD. -FAU - Andrus, Miranda R -AU - Andrus MR -AD - Auburn University Harrison School of Pharmacy, Huntsville, Alabama 35801, USA. -FAU - Loyed, Joyce V -AU - Loyed JV -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Drugs Aging -JT - Drugs & aging -JID - 9102074 -RN - 0 (Adrenergic beta-Antagonists) -SB - IM -MH - Adrenergic beta-Antagonists/adverse effects/pharmacokinetics/*therapeutic use -MH - Age Factors -MH - Aged -MH - Cardiovascular Diseases/complications/*drug therapy/mortality -MH - Clinical Trials as Topic -MH - Heart Failure/complications/drug therapy -MH - Humans -MH - Meta-Analysis as Topic -MH - Pulmonary Disease, Chronic Obstructive/*complications/mortality -RF - 57 -EDAT- 2008/02/09 09:00 -MHDA- 2008/05/02 09:00 -CRDT- 2008/02/09 09:00 -PHST- 2008/02/09 09:00 [pubmed] -PHST- 2008/05/02 09:00 [medline] -PHST- 2008/02/09 09:00 [entrez] -AID - 2525 [pii] -AID - 10.2165/00002512-200825020-00005 [doi] -PST - ppublish -SO - Drugs Aging. 2008;25(2):131-44. doi: 10.2165/00002512-200825020-00005. - -PMID- 23098146 -OWN - NLM -STAT- MEDLINE -DCOM- 20130404 -LR - 20211021 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Linking) -VI - 10 -IP - 9 -DP - 2012 Sep -TI - MRI of acute vascular syndromes: the emerging role of cardiovascular MRI in the - diagnosis and treatment of AMI and stroke. -PG - 1101-8 -LID - 10.1586/erc.12.65 [doi] -AB - MRI is a safe and reproducible noninvasive method of obtaining high-resolution - images of the heart and vascular system. As MRI has developed a more widespread - clinical application over the last decade, attention has been increasing on how - this technique can be used to aid the diagnosis of cardio- and cerebro-vascular - diseases in the acute setting. While much of the initial development of cardiac - MRI was based around describing the myocardium in the chronic stable state, much - recent research has investigated the use of MRI to assess acute coronary - syndromes. Similarly, arterial wall imaging using MRI was initially confined to - relatively stable research populations; however, more recent work has suggested a - possible future clinical role for vascular MRI techniques in acute settings. This - study highlights recent advances in MRI of the cardiovascular system, with a - particular emphasis on those techniques that can be of use in the setting of - acute vascular syndromes, namely acute coronary syndrome, transient ischemic - attack and stroke. -FAU - Lindsay, Alistair C -AU - Lindsay AC -AD - Department of Cardiology, Royal Brompton Hospital, London, UK. -FAU - Choudhury, Robin P -AU - Choudhury RP -LA - eng -GR - 088291/Wellcome Trust/United Kingdom -GR - 090532/Wellcome Trust/United Kingdom -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -RN - 0 (Contrast Media) -SB - IM -MH - Acute Disease -MH - Angina, Unstable/diagnosis/pathology/therapy -MH - *Cerebrovascular Circulation -MH - Contrast Media -MH - *Coronary Circulation -MH - Humans -MH - Ischemic Attack, Transient/diagnosis/pathology/therapy -MH - Magnetic Resonance Angiography/trends -MH - Magnetic Resonance Imaging, Interventional/trends -MH - Microvessels/pathology/physiopathology -MH - Myocardial Infarction/*diagnosis/pathology/physiopathology/*therapy -MH - Plaque, Atherosclerotic/diagnosis/pathology/therapy -MH - Stroke/*diagnosis/pathology/*therapy -MH - Ventricular Dysfunction/etiology -EDAT- 2012/10/27 06:00 -MHDA- 2013/04/05 06:00 -CRDT- 2012/10/27 06:00 -PHST- 2012/10/27 06:00 [entrez] -PHST- 2012/10/27 06:00 [pubmed] -PHST- 2013/04/05 06:00 [medline] -AID - 10.1586/erc.12.65 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2012 Sep;10(9):1101-8. doi: 10.1586/erc.12.65. - -PMID- 16543510 -OWN - NLM -STAT- MEDLINE -DCOM- 20060330 -LR - 20220408 -IS - 1524-4571 (Electronic) -IS - 0009-7330 (Linking) -VI - 98 -IP - 5 -DP - 2006 Mar 17 -TI - Diabetic cardiomyopathy: the search for a unifying hypothesis. -PG - 596-605 -AB - Although diabetes is recognized as a potent and prevalent risk factor for - ischemic heart disease, less is known as to whether diabetes causes an altered - cardiac phenotype independent of coronary atherosclerosis. Left ventricular - systolic and diastolic dysfunction, left ventricular hypertrophy, and alterations - in the coronary microcirculation have all been observed, although not - consistently, in diabetic cardiomyopathy and are not fully explained by the - cellular effects of hyperglycemia alone. The recent recognition that diabetes - involves more than abnormal glucose homeostasis provides important new - opportunities to examine and understand the impact of complex metabolic - disturbances on cardiac structure and function. -FAU - Poornima, Indu G -AU - Poornima IG -AD - Department of Medicine, Allegheny General Hospital, Pittsburgh, PA 15212, USA. -FAU - Parikh, Pratik -AU - Parikh P -FAU - Shannon, Richard P -AU - Shannon RP -LA - eng -GR - R01-AG 023125/AG/NIA NIH HHS/United States -GR - R01-HL75836/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Circ Res -JT - Circulation research -JID - 0047103 -RN - 0 (Fatty Acids, Nonesterified) -RN - EC 2.7.1.- (Phosphatidylinositol 3-Kinases) -RN - EC 2.7.11.1 (AKT1 protein, human) -RN - EC 2.7.11.1 (Proto-Oncogene Proteins c-akt) -SB - IM -MH - Animals -MH - Cardiomyopathies/*etiology -MH - Coronary Circulation -MH - Diabetes Complications/*etiology/pathology/physiopathology -MH - Diabetes Mellitus, Type 1/complications -MH - Diabetes Mellitus, Type 2/complications -MH - Fatty Acids, Nonesterified/blood -MH - Humans -MH - Hyperglycemia/complications -MH - Hyperinsulinism/complications -MH - Hypertrophy, Left Ventricular/etiology -MH - Insulin Resistance -MH - Phosphatidylinositol 3-Kinases/physiology -MH - Proto-Oncogene Proteins c-akt/physiology -MH - Ventricular Dysfunction, Left/etiology -RF - 98 -EDAT- 2006/03/18 09:00 -MHDA- 2006/03/31 09:00 -CRDT- 2006/03/18 09:00 -PHST- 2006/03/18 09:00 [pubmed] -PHST- 2006/03/31 09:00 [medline] -PHST- 2006/03/18 09:00 [entrez] -AID - 98/5/596 [pii] -AID - 10.1161/01.RES.0000207406.94146.c2 [doi] -PST - ppublish -SO - Circ Res. 2006 Mar 17;98(5):596-605. doi: 10.1161/01.RES.0000207406.94146.c2. - -PMID- 23314545 -OWN - NLM -STAT- MEDLINE -DCOM- 20130905 -LR - 20161018 -IS - 1437-4331 (Electronic) -IS - 1434-6621 (Linking) -VI - 51 -IP - 3 -DP - 2013 Mar 1 -TI - Mechanisms of the beneficial effects of vitamin B6 and pyridoxal 5-phosphate on - cardiac performance in ischemic heart disease. -PG - 535-43 -LID - 10.1515/cclm-2012-0553 [doi] -AB - Although vitamin B6 and its metabolite, pyridoxal 5'-phosphate (PLP), have been - shown to exert beneficial effects in ischemic heart disease, the mechanisms of - their action are not fully understood. Some studies have shown that ventricular - arrhythmias and mortality upon the occlusion of coronary artery were attenuated - by pretreatment of animals with PLP. Furthermore, ischemia-reperfusion-induced - abnormalities in cardiac performance and defects in sarcoplasmic reticular - Ca2+-transport activities were decreased by PLP. The increase in cardiac - contractile activity of isolated heart by ATP was reduced by PLP, unlike - propranolol, whereas that by isoproterenol was not depressed by PLP. ATP-induced - increase in [Ca2+]i, unlike KCl-induced increase in [Ca2+]i in cardiomyocytes was - depressed by PLP. Both high- and low-affinity sites for ATP binding in - sarcolemmal membranes were also decreased by PLP. These observations support the - view that PLP may produce cardioprotective effects in ischemic heart disease by - attenuating the occurrence of intracellular Ca2+ overload due to the blockade of - purinergic receptors. -FAU - Dhalla, Naranjan S -AU - Dhalla NS -AD - Institute of Cardiovascular Sciences, St. Boniface Hospital Research, Faculty of - Medicine, Department of Physiology, University of Manitoba, Winnipeg, Manitoba, - R2H 2A6 Canada. nsdhalla@sbrc.ca -FAU - Takeda, Satoshi -AU - Takeda S -FAU - Elimban, Vijayan -AU - Elimban V -LA - eng -GR - Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Germany -TA - Clin Chem Lab Med -JT - Clinical chemistry and laboratory medicine -JID - 9806306 -RN - 0 (Cardiotonic Agents) -RN - 5V5IOJ8338 (Pyridoxal Phosphate) -RN - 8059-24-3 (Vitamin B 6) -SB - IM -MH - Animals -MH - Cardiotonic Agents/metabolism/pharmacology/therapeutic use -MH - Heart/drug effects/physiology -MH - Myocardial Ischemia/*drug therapy/metabolism/pathology -MH - Pyridoxal Phosphate/metabolism/pharmacology/*therapeutic use -MH - Reperfusion Injury/drug therapy/metabolism/pathology -MH - Vitamin B 6/metabolism/pharmacology/*therapeutic use -MH - Vitamin B 6 Deficiency/drug therapy/metabolism/pathology -EDAT- 2013/01/15 06:00 -MHDA- 2013/09/06 06:00 -CRDT- 2013/01/15 06:00 -PHST- 2012/08/28 00:00 [received] -PHST- 2012/11/09 00:00 [accepted] -PHST- 2013/01/15 06:00 [entrez] -PHST- 2013/01/15 06:00 [pubmed] -PHST- 2013/09/06 06:00 [medline] -AID - /j/cclm.ahead-of-print/cclm-2012-0553/cclm-2012-0553.xml [pii] -AID - 10.1515/cclm-2012-0553 [doi] -PST - ppublish -SO - Clin Chem Lab Med. 2013 Mar 1;51(3):535-43. doi: 10.1515/cclm-2012-0553. - -PMID- 19648389 -OWN - NLM -STAT- MEDLINE -DCOM- 20090821 -LR - 20231024 -IS - 1942-5546 (Electronic) -IS - 0025-6196 (Print) -IS - 0025-6196 (Linking) -VI - 84 -IP - 8 -DP - 2009 Aug -TI - Beta-blocker use for the stages of heart failure. -PG - 718-29 -LID - 10.4065/84.8.718 [doi] -AB - The 2005 American Heart Association/American College of Cardiology heart failure - (HF) guidelines contributed to a renewed focus on "at-risk" patients and - emphasized HF as a progressive disease. Patient categorization by stages focused - attention on customization of therapy to achieve optimal, evidence-based - treatments across the HF continuum. Therapy for risk factors that predispose - patients to left ventricular dysfunction or other symptoms may help reduce HF - development. beta-Blockers are valuable for treatment of HF; however, the class - is heterogeneous, and proper beta-blocker selection for each HF stage is - important. beta-Blockers have been used routinely to treat patients with stage A - HF with hypertension. Recent controversy regarding the detrimental effects that - some beta-blockers have on metabolic parameters has raised inappropriate concerns - about the use of any beta-blocker for diabetes. beta-Blockade is standard therapy - for the patient with stage B HF who has had a myocardial infarction, but few data - are available concerning use in asymptomatic patients with left ventricular - dysfunction. Additionally, beta-blockers are part of the core therapy for stage C - HF and selected patients with stage D HF. This review examines the role and use - of beta-blockers in each HF stage through an evidence-based approach to provide - better understanding of their importance in this progressive disease. PubMed - searches (1980-2008) identified large clinical trials that evaluated - cardiovascular events and outcomes in any HF stage or hypertension. Search terms - were heart failure, hypertension, beta-blocker, ACEI, ARB, and calcium channel - blocker AND blood pressure coronary artery disease, diabetes, efficacy, left - ventricular dysfunction, metabolism, mortality, myocardial infarction, or stroke. -FAU - Klapholz, Marc -AU - Klapholz M -AD - Division of Cardiology, University of Medicine and Dentistry of New Jersey, - Newark, New Jersey 07103-2714, USA. klapholz@umdnj.edu -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Mayo Clin Proc -JT - Mayo Clinic proceedings -JID - 0405543 -RN - 0 (Adrenergic beta-Antagonists) -SB - IM -MH - Adrenergic beta-Antagonists/*administration & dosage/adverse effects -MH - Diabetes Mellitus/diagnosis/epidemiology -MH - Disease Progression -MH - Dose-Response Relationship, Drug -MH - Drug Administration Schedule -MH - Evidence-Based Medicine -MH - Female -MH - Follow-Up Studies -MH - Heart Failure/*diagnosis/*drug therapy/epidemiology -MH - Humans -MH - Hypertension/diagnosis/epidemiology -MH - Male -MH - *Practice Guidelines as Topic -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - Severity of Illness Index -MH - Survival Analysis -MH - Treatment Outcome -PMC - PMC2719525 -EDAT- 2009/08/04 09:00 -MHDA- 2009/08/22 09:00 -PMCR- 2010/02/01 -CRDT- 2009/08/04 09:00 -PHST- 2009/08/04 09:00 [entrez] -PHST- 2009/08/04 09:00 [pubmed] -PHST- 2009/08/22 09:00 [medline] -PHST- 2010/02/01 00:00 [pmc-release] -AID - 84/8/718 [pii] -AID - 0840718 [pii] -AID - 10.4065/84.8.718 [doi] -PST - ppublish -SO - Mayo Clin Proc. 2009 Aug;84(8):718-29. doi: 10.4065/84.8.718. - -PMID- 19422273 -OWN - NLM -STAT- MEDLINE -DCOM- 20090729 -LR - 20230823 -IS - 1083-4087 (Print) -IS - 1944-706X (Electronic) -IS - 1083-4087 (Linking) -VI - 15 -IP - 4 -DP - 2009 May -TI - Critical review of prasugrel for formulary decision makers. -PG - 335-43 -LID - 10.18553/jmcp.2009.15.4.335 -AB - BACKGROUND: Cardiovascular disease, including acute coronary syndromes (ACS) - comprising ST-elevation and non-ST-elevation myocardial infarction (STEMI/NSTEMI) - and unstable angina (UA), remains the leading cause of death in the United - States. The direct and indirect costs of cardiovascular disease are estimated to - surpass $165 billion in 2009. Antiplatelet pharmacotherapy has been shown to - reduce ACS-related death and is part of the American College of Chest Physicians - (ACCP) and the American College of Cardiology /American Heart Association - (ACC/AHA) treatment guideline recommendations. OBJECTIVE: To provide formulary - decision makers with information on the pharmacokinetics and pharmacodynamics of - the thienopyridine antiplatelet agent prasugrel as well as an analysis of - available efficacy and safety data and its risk-benefit profile in comparison - with clopidogrel. METHODS: Literature search for information on prasugrel with a - focus on (a) the Trial to Assess Improvement in Therapeutic Outcomes by - Optimizing Platelet Inhibition with Prasugrel-Thrombolysis in Myocardial - Infarction (TRITON-TIMI) 38 trial, (b) briefing documents from the FDA available - as of March 1, 2009, and (c) ongoing phase III studies of prasugrel. RESULTS: - TRITON-TIMI 38 was a double blind, randomized superiority study involving 13,608 - patients with moderate-to high-risk acute coronary syndromes with scheduled - percutaneous coronary intervention (PCI). TRITON-TIMI 38 data were available in a - published manuscript and in an FDA review. Study patients were randomized to - either prasugrel or clopidogrel once daily. The primary end point (composite of - death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal - stroke) occurred in 643 patients (9.9%) in the prasugrel group and 781 patients - (12.1%) in the clopidogrel group (HR = 0.82, 95% CI = 0.73-0.93, P = 0.002). - Non-coronary artery bypass graft (non-CABG) TIMI major hemorrhage occurred in 146 - patients (2.4%) in the prasugrel group compared with 111 patients (1.8%) in the - clopidogrel group (HR=1.32, 95% CI=1.03-1.68, P = 0.03). A subanalysis of the - TRITON-TIMI 38 trial data revealed a net harm for patients with a prior history - of stroke or transient ischemic attack (TIA) when treated with prasugrel (HR = - 1.54, 95% CI = 1.02-2.32, P = 0.04). Combination prasugrel and aspirin is - currently being studied in comparison with clopidogrel and aspirin for the - treatment of UA/NSTEMI patients that are medically managed. CONCLUSIONS: For - every 1,000 patients treated with prasugrel instead of clopidogrel, a total of 24 - end points would be prevented at the cost of 10 additional bleeding events. On - February 3, 2009, the FDA Cardiovascular and Renal Drugs Advisory Committee - deemed this to be an acceptable riskbenefit profile. The committee recommended a - label contraindication for patients with prior history of transient ischemic - attack or stroke. Treatment versus time analyses demonstrated both early and - sustained benefit for prasugrel compared with clopidogrel. However, prasugrel was - associated with fewer cardiovascular events prevented per bleeding case the - longer the duration of therapy. The study population of TRITON-TIMI 38 was - limited to patients undergoing PCI. Managed care decision makers should consider - specific criteria limiting prasugrel use to health plan members with - characteristics similar to the study population in TRITON-TIMI 38 that benefited - from treatment and avoiding use in patients with prior history of stroke or TIA. - More data are needed before prasugrel can be recommended in patient groups not - addressed by TRITON-TIMI 38. -FAU - Schafer, Jeremy A -AU - Schafer JA -AD - Prime Therapeutics, 1305 Corporate Center Drive, Eagan, MN 55121, USA. - jschafer@primetherapeutics.com -FAU - Kjesbo, Nicole K -AU - Kjesbo NK -FAU - Gleason, Patrick P -AU - Gleason PP -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - United States -TA - J Manag Care Pharm -JT - Journal of managed care pharmacy : JMCP -JID - 9605854 -RN - 0 (Piperazines) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Thiophenes) -RN - A74586SNO7 (Clopidogrel) -RN - G89JQ59I13 (Prasugrel Hydrochloride) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -CIN - J Manag Care Pharm. 2009 Jun;15(5):414-6. doi: 10.18553/jmcp.2009.15.5.414. PMID: - 19496638 -MH - Angioplasty, Balloon, Coronary/economics -MH - Clopidogrel -MH - Drug Interactions -MH - Formularies, Hospital as Topic/*standards -MH - Humans -MH - Managed Care Programs/economics -MH - Myocardial Infarction/drug therapy -MH - *Piperazines/adverse effects/pharmacokinetics/pharmacology/therapeutic use -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Prasugrel Hydrochloride -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - *Thiophenes/adverse effects/pharmacokinetics/pharmacology/therapeutic use -MH - Ticlopidine/analogs & derivatives/therapeutic use -PMC - PMC10437689 -EDAT- 2009/05/09 09:00 -MHDA- 2009/07/30 09:00 -PMCR- 2009/05/01 -CRDT- 2009/05/09 09:00 -PHST- 2009/05/09 09:00 [entrez] -PHST- 2009/05/09 09:00 [pubmed] -PHST- 2009/07/30 09:00 [medline] -PHST- 2009/05/01 00:00 [pmc-release] -AID - 2009(15)4: 335-343 [pii] -AID - 10.18553/jmcp.2009.15.4.335 [doi] -PST - ppublish -SO - J Manag Care Pharm. 2009 May;15(4):335-43. doi: 10.18553/jmcp.2009.15.4.335. - -PMID- 18389781 -OWN - NLM -STAT- MEDLINE -DCOM- 20080703 -LR - 20161124 -IS - 0048-7848 (Print) -IS - 0048-7848 (Linking) -VI - 111 -IP - 4 -DP - 2007 Oct-Dec -TI - [Echocardiographic evaluation of left ventricular diastolic dysfunction in - patients with diabetes mellitus]. -PG - 922-4 -AB - The presence of diabetic cardiomyopathy, without any sign of hypertension, - valvular or coronary artery disease, is related to diastolic dysfunction, an - early sign of diabetic heart muscle disease. Doppler echocardiography evaluation - should be performed for all patients with type 2 diabetes mellitus and - microalbuminuria, in order to obtain a better management of this metabolic - disease. -FAU - Bălăceanu, Alice -AU - Bălăceanu A -AD - Spitalul Judeţean Ilfov "Sfinţii Impăraţi C-tin si Elena", Bucureşti. -FAU - Sopa, Angela -AU - Sopa A -FAU - Diaconu, Camelia -AU - Diaconu C -FAU - Ionescu, Ecaterina -AU - Ionescu E -LA - rum -PT - Journal Article -PT - Review -TT - Evaluarea ecocardiografică a disfunctiei diastolice de ventricul stâng la - pacienţii cu diabet zaharat. -PL - Romania -TA - Rev Med Chir Soc Med Nat Iasi -JT - Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi -JID - 0413735 -SB - IM -MH - Diabetes Mellitus, Type 2/complications/*diagnostic imaging/physiopathology -MH - *Diastole -MH - *Echocardiography, Doppler/methods -MH - Humans -MH - Reproducibility of Results -MH - Ventricular Dysfunction, Left/complications/*diagnostic imaging/physiopathology -RF - 11 -EDAT- 2008/04/09 09:00 -MHDA- 2008/07/04 09:00 -CRDT- 2008/04/09 09:00 -PHST- 2008/04/09 09:00 [pubmed] -PHST- 2008/07/04 09:00 [medline] -PHST- 2008/04/09 09:00 [entrez] -PST - ppublish -SO - Rev Med Chir Soc Med Nat Iasi. 2007 Oct-Dec;111(4):922-4. - -PMID- 23381830 -OWN - NLM -STAT- MEDLINE -DCOM- 20140115 -LR - 20231213 -IS - 1678-2674 (Electronic) -IS - 0102-8650 (Linking) -VI - 28 Suppl 1 -DP - 2013 -TI - Is rosmarinic acid underestimated as an experimental cardiovascular drug? -PG - 83-7 -LID - S0102-86502013001300016 [pii] -AB - PURPOSE: The rationale of the present review is to analize the activity of - Rosmarinus officinalis in the the cardiovascular system METHODS: A MEDLINE - database search (from January 1970 to December 2011) using only rosmarinic acid - as searched term. RESULTS: The references search revealed 509 references about - rosmarinic acid in 40 years (the first reference is from 1970). There is a - powerful prevalence of antioxidant and cancer studies. Other diseases are few - cited, as inflammation, brain (Alzheimer and Parkinson disease) and, memory; - allergy; diabetes; atherosclerosis, and; hypertension. It is necessary to - consider the complete absence of studies on coronary artery disease, myocardial - ischemia, heart failure or ischemia/reperfusion injury. CONCLUSION: Rosmarinic - acid is underestimated as an experimental cardiovascular drug and deserves more - attention. -FAU - Ferreira, Luciana Garros -AU - Ferreira LG -AD - Postgraduate Program in Medical Surgical Clinic, Department of Surgery and - Anatomy, Ribeirão Preto Faculty of Medicine, University of São Paulo, Ribeirão - Preto, SP, Brazil. -FAU - Celotto, Andrea Carla -AU - Celotto AC -FAU - Capellini, Verena Kise -AU - Capellini VK -FAU - Albuquerque, Agnes Afrodite Sumarelli -AU - Albuquerque AA -FAU - Nadai, Tales Rubens de -AU - Nadai TR -FAU - Carvalho, Marco Tulio Menezes de -AU - Carvalho MT -FAU - Evora, Paulo Roberto Barbosa -AU - Evora PR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Brazil -TA - Acta Cir Bras -JT - Acta cirurgica brasileira -JID - 9103983 -RN - 0 (Cardiovascular Agents) -RN - 0 (Cinnamates) -RN - 0 (Depsides) -SB - IM -MH - Cardiovascular Agents/pharmacology/*therapeutic use -MH - Cardiovascular Diseases/*drug therapy -MH - Cinnamates/pharmacology/*therapeutic use -MH - Depsides/pharmacology/*therapeutic use -MH - Humans -MH - Rosmarinic Acid -EDAT- 2013/02/13 06:00 -MHDA- 2014/01/16 06:00 -CRDT- 2013/02/06 06:00 -PHST- 2013/02/06 06:00 [entrez] -PHST- 2013/02/13 06:00 [pubmed] -PHST- 2014/01/16 06:00 [medline] -AID - S0102-86502013001300016 [pii] -AID - 10.1590/s0102-86502013001300016 [doi] -PST - ppublish -SO - Acta Cir Bras. 2013;28 Suppl 1:83-7. doi: 10.1590/s0102-86502013001300016. - -PMID- 22505527 -OWN - NLM -STAT- MEDLINE -DCOM- 20120810 -LR - 20220408 -IS - 1437-4331 (Electronic) -IS - 1434-6621 (Linking) -VI - 50 -IP - 4 -DP - 2011 Dec 17 -TI - The role of red blood cell distribution width in cardiovascular and thrombotic - disorders. -PG - 635-41 -LID - /j/cclm.2012.50.issue-4/cclm.2011.831/cclm.2011.831.xml [pii] -LID - 10.1515/cclm.2011.831 [doi] -AB - The red blood cell (RBC) distribution width (RDW) is a measurement of the size - variation as well as an index of the heterogeneity of the erythrocytes (i.e., - anysocytosis), which is typically used in combination with the mean corpuscular - volume to troubleshoot the cause of an underlying anemia. Reliable data emerged - from a variety of clinical studies have, however, disclosed a new and - unpredictable scenario in the clinical usefulness of this measure, supporting the - hypothesis that RDW might be a useful parameter for gathering meaningful clinical - information, either diagnostic or prognostic, on a variety of cardiovascular and - thrombotic disorders. Highly significant associations have been described between - RDW value and all-cause, non-cardiac and cardiac mortality in patients with - coronary artery disease, acute and chronic heart failure, peripheral artery - disease, stroke, pulmonary embolism and pulmonary arterial hypertension. It is - however still unclear whether anysocytosis might be the cause, or a simple - epiphenomenon of an underlying disease, such as inflammation, impaired renal - function, undernutrition, oxidative damage, or perhaps an element of both. - Nevertheless, RDW is an easy, inexpensive, routinely reported test, whose - assessment might allow the acquisition of significant diagnostic and prognostic - information in patients with cardiovascular and thrombotic disorders. -FAU - Montagnana, Martina -AU - Montagnana M -AD - Sezione di Biochimica Clinica, Dipartimento di Scienze della Vita e della - Riproduzione, Universit à degli Studi di Verona, Verona, Italy. -FAU - Cervellin, Gianfranco -AU - Cervellin G -FAU - Meschi, Tiziana -AU - Meschi T -FAU - Lippi, Giuseppe -AU - Lippi G -LA - eng -PT - Journal Article -PT - Review -DEP - 20111217 -PL - Germany -TA - Clin Chem Lab Med -JT - Clinical chemistry and laboratory medicine -JID - 9806306 -SB - IM -MH - Cardiovascular Diseases/mortality/*pathology -MH - *Cell Size -MH - Erythrocytes/*pathology -MH - Humans -MH - Thrombosis/mortality/*pathology -EDAT- 2012/04/17 06:00 -MHDA- 2012/08/11 06:00 -CRDT- 2012/04/17 06:00 -PHST- 2011/10/15 00:00 [received] -PHST- 2011/11/30 00:00 [accepted] -PHST- 2012/04/17 06:00 [entrez] -PHST- 2012/04/17 06:00 [pubmed] -PHST- 2012/08/11 06:00 [medline] -AID - /j/cclm.2012.50.issue-4/cclm.2011.831/cclm.2011.831.xml [pii] -AID - 10.1515/cclm.2011.831 [doi] -PST - epublish -SO - Clin Chem Lab Med. 2011 Dec 17;50(4):635-41. doi: 10.1515/cclm.2011.831. - -PMID- 17979778 -OWN - NLM -STAT- MEDLINE -DCOM- 20080205 -LR - 20190907 -IS - 1873-4294 (Electronic) -IS - 1568-0266 (Linking) -VI - 7 -IP - 17 -DP - 2007 -TI - NPY and cardiac diseases. -PG - 1692-703 -AB - Hypertension-induced left ventricular hypertrophy (LVH), along with ischemic - heart disease, result in LV remodeling as part of a continuum that often leads to - congestive heart failure. The neurohormonal model has been used to underpin many - treatment strategies, but optimal outcomes have not been achieved. Neuropeptide Y - (NPY) has emerged as an additional therapeutic target, ever since it was - recognised as an important mediator released from sympathetic nerves in the - heart, affecting coronary artery constriction and myocardial contraction. More - recent interest has focused on the mitogenic and hypertrophic effects that are - observed in endothelial and vascular smooth muscle cells, and cardiac myocytes. - Of the six identified NPY receptor subtypes, Y(1), Y(2) and Y(5) appear to - mediate the main functional responses in the heart. Plasma levels of NPY become - elevated due to the increased sympathetic activation present in stress-related - cardiac conditions. Also, NPY and Y receptor polymorphisms have been identified - that may predispose individuals to increased risk of hypertension and cardiac - complications. This review examines what understanding exists regarding the - likely contribution of NPY to cardiac pathology. It appears that NPY may play a - part in compensatory or detrimental remodeling of myocardial tissue subsequent to - hemodynamic overload or myocardial infarction, and in angiogenic processes to - regenerate myocardium after ischemic injury. However, greater mechanistic - information is required in order to truly assess the potential for treatment of - cardiac diseases using NPY-based drugs. -FAU - McDermott, B J -AU - McDermott BJ -AD - Therapeutics & Pharmacology, Queen's University Belfast, Whitla Medical Building, - 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland. b.mcdermott@qub.ac.uk -FAU - Bell, D -AU - Bell D -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Top Med Chem -JT - Current topics in medicinal chemistry -JID - 101119673 -RN - 0 (Neuropeptide Y) -SB - IM -MH - Animals -MH - Heart Diseases/*metabolism/pathology -MH - Humans -MH - Neuropeptide Y/*metabolism -MH - Ventricular Dysfunction, Left -MH - Ventricular Remodeling -RF - 161 -EDAT- 2007/11/06 09:00 -MHDA- 2008/02/06 09:00 -CRDT- 2007/11/06 09:00 -PHST- 2007/11/06 09:00 [pubmed] -PHST- 2008/02/06 09:00 [medline] -PHST- 2007/11/06 09:00 [entrez] -AID - 10.2174/156802607782340939 [doi] -PST - ppublish -SO - Curr Top Med Chem. 2007;7(17):1692-703. doi: 10.2174/156802607782340939. - -PMID- 21856484 -OWN - NLM -STAT- MEDLINE -DCOM- 20110913 -LR - 20250529 -IS - 1474-547X (Electronic) -IS - 0140-6736 (Print) -IS - 0140-6736 (Linking) -VI - 378 -IP - 9792 -DP - 2011 Aug 20 -TI - In search of new therapeutic targets and strategies for heart failure: recent - advances in basic science. -PG - 704-12 -LID - 10.1016/S0140-6736(11)60894-5 [doi] -AB - Chronic heart failure continues to impose a substantial health-care burden, - despite recent treatment advances. The key pathophysiological process that - ultimately leads to chronic heart failure is cardiac remodelling in response to - chronic disease stresses. Here, we review recent advances in our understanding of - molecular and cellular mechanisms that play a part in the complex remodelling - process, with a focus on key molecules and pathways that might be suitable - targets for therapeutic manipulation. Such pathways include those that regulate - cardiac myocyte hypertrophy, calcium homoeostasis, energetics, and cell survival, - and processes that take place outside the cardiac myocyte--eg, in the myocardial - vasculature and extracellular matrix. We also discuss major gaps in our current - understanding, take a critical look at conventional approaches to target - discovery that have been used to date, and consider new investigational avenues - that might accelerate clinically relevant discovery. -CI - Copyright © 2011 Elsevier Ltd. All rights reserved. -FAU - Shah, Ajay M -AU - Shah AM -AD - King's College London British Heart Foundation Centre of Excellence, London, UK. - ajay.shah@kcl.ac.uk -FAU - Mann, Douglas L -AU - Mann DL -LA - eng -GR - HL089543/HL/NHLBI NIH HHS/United States -GR - HL73017/HL/NHLBI NIH HHS/United States -GR - R01 HL089543/HL/NHLBI NIH HHS/United States -GR - R01 HL073017/HL/NHLBI NIH HHS/United States -GR - R01 HL58081/HL/NHLBI NIH HHS/United States -GR - R01 HL058081/HL/NHLBI NIH HHS/United States -GR - RG/08/011/25922/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Lancet -JT - Lancet (London, England) -JID - 2985213R -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Animals -MH - Apoptosis -MH - Calcium/metabolism -MH - Chronic Disease -MH - Coronary Circulation -MH - Extracellular Matrix/physiology -MH - Heart Failure/*drug therapy/*physiopathology -MH - Humans -MH - Myocytes, Cardiac/physiology -MH - Signal Transduction -MH - Ventricular Remodeling/physiology -PMC - PMC3486638 -MID - NIHMS412578 -EDAT- 2011/08/23 06:00 -MHDA- 2011/09/14 06:00 -PMCR- 2012/11/01 -CRDT- 2011/08/23 06:00 -PHST- 2011/08/23 06:00 [entrez] -PHST- 2011/08/23 06:00 [pubmed] -PHST- 2011/09/14 06:00 [medline] -PHST- 2012/11/01 00:00 [pmc-release] -AID - S0140-6736(11)60894-5 [pii] -AID - 10.1016/S0140-6736(11)60894-5 [doi] -PST - ppublish -SO - Lancet. 2011 Aug 20;378(9792):704-12. doi: 10.1016/S0140-6736(11)60894-5. - -PMID- 20845891 -OWN - NLM -STAT- MEDLINE -DCOM- 20101005 -LR - 20250529 -IS - 0966-8519 (Print) -IS - 0966-8519 (Linking) -VI - 19 -IP - 4 -DP - 2010 Jul -TI - Insights into the use of biomarkers in calcific aortic valve disease. -PG - 441-52 -AB - Calcific aortic valve disease (CAVD) is the most common acquired valvular - disorder in developed countries. CAVD ranges from mild thickening of the valve, - known as aortic valve sclerosis (AVSc), to severe impairment of the valve motion, - which is termed aortic valve stenosis (AVS). The prevalence of CAVD is nearing - epidemic status: its preceding stage, in which there is aortic sclerosis without - obstruction of the left ventricular outflow, is present in almost 30% of adults - aged over 65 years. As there is no existing medical therapy to treat or slow the - progression of CAVD, surgery for advanced disease represents the only available - treatment. Aortic valve replacement is the second most frequently performed - cardiac surgical procedure after coronary artery bypass grafting, and - consequently CAVD represents a major societal and economic burden. The - pathophysiological development of CAVD is incompletely defined. At the present - time, the major methods for its diagnosis are clinical examination, - echocardiography, and cardiac catheterization. Yet, due to the multiple - biological pathways leading to CAVD, there are many potential biomarkers that - might be suitable for deriving clinically useful information regarding the - presence, severity, progression, and prognosis of CAVD. Although at the present - time the available data do not permit recommendations for clinicians, they do - support a paradigm of screening patients based on multiple biomarkers to provide - the information necessary to optimize future therapeutic interventions. This - review summarizes the results of several studies investigating the value of - potential biomarkers that have been used to predict the severity, progression, - and prognosis of CAVD. -FAU - Beckmann, Erik -AU - Beckmann E -AD - Department of Surgery, Division of Cardiovascular Surgery, University of - Pennsylvania School of Medicine, Philadelphia 19036, USA. -FAU - Grau, Juan B -AU - Grau JB -FAU - Sainger, Rachana -AU - Sainger R -FAU - Poggio, Paolo -AU - Poggio P -FAU - Ferrari, Giovanni -AU - Ferrari G -LA - eng -GR - RC1 HL100035/HL/NHLBI NIH HHS/United States -GR - RC1HL100035/RC/CCR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - England -TA - J Heart Valve Dis -JT - The Journal of heart valve disease -JID - 9312096 -RN - 0 (Biomarkers) -SB - IM -MH - Animals -MH - Aortic Valve/*metabolism/pathology/surgery -MH - Aortic Valve Stenosis/blood/*diagnosis/pathology/surgery -MH - Biomarkers/*blood -MH - Calcinosis/blood/*diagnosis/pathology/surgery -MH - Disease Progression -MH - Heart Valve Diseases/blood/*diagnosis/pathology/surgery -MH - Heart Valve Prosthesis Implantation -MH - Humans -MH - Predictive Value of Tests -MH - Prognosis -MH - Sclerosis -MH - Severity of Illness Index -PMC - PMC2941903 -MID - NIHMS214883 -COIS- None of the authors of this paper have any financial interest in the data - presented. -EDAT- 2010/09/18 06:00 -MHDA- 2010/10/06 06:00 -PMCR- 2010/09/20 -CRDT- 2010/09/18 06:00 -PHST- 2010/09/18 06:00 [entrez] -PHST- 2010/09/18 06:00 [pubmed] -PHST- 2010/10/06 06:00 [medline] -PHST- 2010/09/20 00:00 [pmc-release] -PST - ppublish -SO - J Heart Valve Dis. 2010 Jul;19(4):441-52. - -PMID- 19664377 -OWN - NLM -STAT- MEDLINE -DCOM- 20091117 -LR - 20211020 -IS - 1534-6242 (Electronic) -IS - 1523-3804 (Linking) -VI - 11 -IP - 5 -DP - 2009 Sep -TI - Low-density lipoprotein in the setting of congestive heart failure: is lower - really better? -PG - 343-9 -AB - Hypercholesterolemia is a risk factor for coronary artery disease (CAD), CAD - mortality, and incident heart failure (HF). Lipid-lowering therapy with - 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) has been - shown to reduce the risk of developing HF in patients with CAD. However, in - patients with chronic established HF, hypercholesterolemia has not been - associated with an increased risk of mortality. Several studies have demonstrated - that higher lipid and lipoprotein levels, including total cholesterol, - low-density lipoprotein, high-density lipoprotein, and triglycerides, are - associated with significantly improved outcomes in HF of both ischemic and - nonischemic etiologies. In light of the association between high cholesterol - levels and improved survival in HF, statin or other lipid-lowering therapy in HF - remains controversial. To date, large outcome trials of statin therapy in HF of - multiple etiologies have not demonstrated mortality benefit. -FAU - Horwich, Tamara -AU - Horwich T -AD - Division of Cardiology, University of California, Los Angeles, CA 90095, USA. - thorwich@mednet.ucla.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Atheroscler Rep -JT - Current atherosclerosis reports -JID - 100897685 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Lipoproteins, LDL) -SB - IM -MH - Global Health -MH - Heart Failure/drug therapy/epidemiology/*etiology -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Hypercholesterolemia/blood/*complications/epidemiology -MH - Incidence -MH - Lipoproteins, LDL/*blood -MH - Prognosis -MH - Risk Factors -MH - Survival Rate -RF - 39 -EDAT- 2009/08/12 09:00 -MHDA- 2009/11/18 06:00 -CRDT- 2009/08/12 09:00 -PHST- 2009/08/12 09:00 [entrez] -PHST- 2009/08/12 09:00 [pubmed] -PHST- 2009/11/18 06:00 [medline] -AID - 10.1007/s11883-009-0052-4 [doi] -PST - ppublish -SO - Curr Atheroscler Rep. 2009 Sep;11(5):343-9. doi: 10.1007/s11883-009-0052-4. - -PMID- 23739627 -OWN - NLM -STAT- MEDLINE -DCOM- 20140127 -LR - 20171116 -IS - 1473-6519 (Electronic) -IS - 1363-1950 (Linking) -VI - 16 -IP - 4 -DP - 2013 Jul -TI - Monocyte gene expression and coronary artery disease. -PG - 411-7 -LID - 10.1097/MCO.0b013e32836236f9 [doi] -AB - PURPOSE OF REVIEW: Despite current therapy, coronary artery disease (CAD) remains - the major cause of morbidity and mortality worldwide. CAD is the consequence of a - complex array of deranged metabolic processes including the immune system. In - this context, monocytes and macrophages are indisputable players. Thus, monocyte - gene expression analysis could be a powerful tool to provide new insights in the - pathophysiology of CAD and improve identification of individuals at risk. We - discuss current literature assessing monocyte gene expression and its association - with CAD. RECENT FINDINGS: Monocyte surface markers CD14 ⁺⁺and CD16⁺ have been - established as biomarkers for increased cardiovascular disease risk in a large - number of studies. More in-depth gene expression analysis identified several - interesting genes, such as ABCA1, CD36 and MSR1 with an increased expression in - circulating monocytes from patients with CAD. The results for CD36 were - replicated in one other study. For ABCA1 and MSR1 conflicting data are published. - SUMMARY: Recent findings indicate that genetic differences exist in circulating - monocytes of patients suffering from CAD, giving us more insights into the - underlying mechanisms. However, larger studies are required to prove that - monocytes' expression signature could serve as a marker for diagnostic purposes - in the future. -FAU - Maiwald, Stephanie -AU - Maiwald S -AD - Department of Vascular Medicine, Academic Medical Center, Amsterdam, The - Netherlands. -FAU - Zwetsloot, Peter-Paul -AU - Zwetsloot PP -FAU - Sivapalaratnam, Suthesh -AU - Sivapalaratnam S -FAU - Dallinga-Thie, Geesje M -AU - Dallinga-Thie GM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Curr Opin Clin Nutr Metab Care -JT - Current opinion in clinical nutrition and metabolic care -JID - 9804399 -RN - 0 (ABCA1 protein, human) -RN - 0 (ATP Binding Cassette Transporter 1) -RN - 0 (Biomarkers) -RN - 0 (CD36 Antigens) -RN - 0 (Lipopolysaccharide Receptors) -RN - 0 (MSR1 protein, human) -RN - 0 (Receptors, IgG) -RN - 0 (Scavenger Receptors, Class A) -SB - IM -MH - ATP Binding Cassette Transporter 1/genetics/metabolism -MH - Biomarkers/metabolism -MH - CD36 Antigens/genetics/metabolism -MH - Coronary Artery Disease/*genetics -MH - *Gene Expression -MH - Gene Expression Profiling -MH - Humans -MH - Lipopolysaccharide Receptors/genetics/metabolism -MH - Monocytes/*metabolism -MH - Receptors, IgG/genetics/metabolism -MH - Scavenger Receptors, Class A/genetics/metabolism -EDAT- 2013/06/07 06:00 -MHDA- 2014/01/28 06:00 -CRDT- 2013/06/07 06:00 -PHST- 2013/06/07 06:00 [entrez] -PHST- 2013/06/07 06:00 [pubmed] -PHST- 2014/01/28 06:00 [medline] -AID - 00075197-201307000-00008 [pii] -AID - 10.1097/MCO.0b013e32836236f9 [doi] -PST - ppublish -SO - Curr Opin Clin Nutr Metab Care. 2013 Jul;16(4):411-7. doi: - 10.1097/MCO.0b013e32836236f9. - -PMID- 23865720 -OWN - NLM -STAT- MEDLINE -DCOM- 20150605 -LR - 20161125 -IS - 1747-0803 (Electronic) -IS - 1747-079X (Linking) -VI - 9 -IP - 5 -DP - 2014 Sep-Oct -TI - Transcatheter aortic valve implantation in surgically repaired double outlet - right ventricle. -PG - E153-7 -LID - 10.1111/chd.12114 [doi] -AB - A 52-year-old male patient, with a medical history of surgically repaired double - outlet right ventricle presented with severe aortic stenosis (AS) and hepatitis C - with cirrhosis, presented with New York Heart Association Class IV heart failure. - During evaluation for a liver transplant, he was deemed a poor surgical candidate - due to his aortic valve disease and cirrhosis with model for end-stage liver - disease score of 14. Transthoracic echocardiogram showed severe AS with a mean - gradient of 62 mm Hg and calculated aortic valve area of 0.74 cm(2) with a normal - ejection fraction of 65%. The patient underwent transfemoral implantation of a - 23-mm Edwards Sapien commercial heart valve with significant mean gradient - reduction across the aortic valve from 62 to 13 mm Hg. The patient was observed - in the coronary care unit and discharged home 2 days postprocedure with his - clinical symptoms greatly improved. -CI - © 2013 Wiley Periodicals, Inc. -FAU - Keswani, Amit -AU - Keswani A -AD - Ochsner Clinic Foundation, Jefferson, La, USA. -FAU - Verma, Anil -AU - Verma A -FAU - Dann, Kristen -AU - Dann K -FAU - Ventura, Laurie -AU - Ventura L -FAU - Lucas, Victor -AU - Lucas V -FAU - Shah, Sangeeta -AU - Shah S -FAU - Ramee, Stephen -AU - Ramee S -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20130719 -PL - United States -TA - Congenit Heart Dis -JT - Congenital heart disease -JID - 101256510 -SB - IM -MH - *Aortic Valve/diagnostic imaging/physiopathology -MH - Aortic Valve Stenosis/diagnosis/physiopathology/*therapy -MH - *Cardiac Catheterization/instrumentation -MH - Double Outlet Right Ventricle/*surgery -MH - Echocardiography, Transesophageal -MH - Heart Valve Prosthesis -MH - Heart Valve Prosthesis Implantation/instrumentation/*methods -MH - Hemodynamics -MH - Humans -MH - Male -MH - Middle Aged -MH - Prosthesis Design -MH - Recovery of Function -MH - Severity of Illness Index -MH - Time Factors -MH - Treatment Outcome -OTO - NOTNLM -OT - Aortic Stenosis -OT - Double Outlet Right Ventricle -OT - TAVI -EDAT- 2013/07/20 06:00 -MHDA- 2015/06/06 06:00 -CRDT- 2013/07/20 06:00 -PHST- 2013/05/27 00:00 [accepted] -PHST- 2013/07/20 06:00 [entrez] -PHST- 2013/07/20 06:00 [pubmed] -PHST- 2015/06/06 06:00 [medline] -AID - 10.1111/chd.12114 [doi] -PST - ppublish -SO - Congenit Heart Dis. 2014 Sep-Oct;9(5):E153-7. doi: 10.1111/chd.12114. Epub 2013 - Jul 19. - -PMID- 19910286 -OWN - NLM -STAT- MEDLINE -DCOM- 20100615 -LR - 20100303 -IS - 1468-201X (Electronic) -IS - 1355-6037 (Linking) -VI - 96 -IP - 5 -DP - 2010 Mar -TI - Cardioversion of atrial fibrillation: the use of antiarrhythmic drugs. -PG - 333-8 -LID - 10.1136/hrt.2008.155812 [doi] -AB - Atrial fibrillation (AF) is the commonest atrial arrhythmia and represents a - large burden on modern health services. Large multicentre randomised trials have - demonstrated that a rhythm control strategy (using antiarrhythmic drugs and - direct current (DC) cardioversion) has no morbidity or mortality advantage over - rate control. Therefore, for most patients, attempts to cardiovert AF to sinus - rhythm (SR) should be reserved for those patients who are symptomatic despite - adequate rate control. For recent-onset AF (<24 h) the use of agents like - flecainide can be highly successful to pharmacologically cardiovert AF, although - caution should be exercised in patients who have the potential for structural or - coronary artery disease because of the risk of proarrhythmia. If there any is - doubt as to the suitability of a patient for pharmacological cardioversion then - DC cardioversion is the safer option. Owing to the high recurrence rate of AF - after cardioversion (71-84% at 1 year), the use of antiarrhythmic drugs to - maintain SR is recommended. The irreversible side effects of amiodarone mean that - it should be avoided whenever possible for long-term maintenance treatment, - although it is useful in short courses (8 weeks-6 months), particularly for - patients who had a successfully treated secondary cause for AF. Other agents like - flecainide and sotalol are also useful but should not be used for patients with - structural heart disease. Data supporting the use of newer agents like - dronedarone are at present limited. -FAU - Schilling, Richard J -AU - Schilling RJ -AD - Department of Cardiology, St Bartholomew's Hospital and Queen Mary University of - London, West Smithfield, London EC1A 7BE, UK. r.schilling@qmul.ac.uk -LA - eng -PT - Journal Article -PT - Review -DEP - 20091111 -PL - England -TA - Heart -JT - Heart (British Cardiac Society) -JID - 9602087 -RN - 0 (Anti-Arrhythmia Agents) -SB - IM -MH - Anti-Arrhythmia Agents/*therapeutic use -MH - Atrial Fibrillation/drug therapy/*therapy -MH - Electric Countershock/*methods -MH - Humans -RF - 53 -EDAT- 2009/11/17 06:00 -MHDA- 2010/06/16 06:00 -CRDT- 2009/11/14 06:00 -PHST- 2009/11/14 06:00 [entrez] -PHST- 2009/11/17 06:00 [pubmed] -PHST- 2010/06/16 06:00 [medline] -AID - hrt.2008.155812 [pii] -AID - 10.1136/hrt.2008.155812 [doi] -PST - ppublish -SO - Heart. 2010 Mar;96(5):333-8. doi: 10.1136/hrt.2008.155812. Epub 2009 Nov 11. - -PMID- 28582099 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20191120 -IS - 2211-7466 (Electronic) -IS - 2211-7458 (Linking) -VI - 1 -IP - 2 -DP - 2012 Apr -TI - Future Perspectives on Percutaneous Coronary Interventions in Women. -PG - 251-258 -LID - S2211-7458(12)00039-9 [pii] -LID - 10.1016/j.iccl.2012.02.003 [doi] -AB - In the United States alone, more than 1 million cardiac catheterizations are - performed each year, with approximately 600,000 patients undergoing percutaneous - coronary intervention (PCI). A meaningful perspective on the future of PCI in - women requires not only reflection on some of the major developments in - interventional cardiology but also a look back more generally at the changing - patterns in the burden of coronary disease in the population and at the gains - accrued in understanding and combating cardiovascular disease in women. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Conroy, Jennifer -AU - Conroy J -AD - Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy - Place, Box 1030, New York, NY 10029, USA. Electronic address: - Jennifer.conroy@mountsinai.org. -FAU - Baber, Usman -AU - Baber U -AD - Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy - Place, Box 1030, New York, NY 10029, USA. -FAU - Mehran, Roxana -AU - Mehran R -AD - Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy - Place, Box 1030, New York, NY 10029, USA. -LA - eng -PT - Journal Article -PT - Review -DEP - 20120410 -PL - Netherlands -TA - Interv Cardiol Clin -JT - Interventional cardiology clinics -JID - 101615153 -OTO - NOTNLM -OT - Coronary disease -OT - Future perspectives -OT - PCI -OT - Percutaneous coronary interventions -OT - Women -EDAT- 2012/04/01 00:00 -MHDA- 2012/04/01 00:01 -CRDT- 2017/06/06 06:00 -PHST- 2017/06/06 06:00 [entrez] -PHST- 2012/04/01 00:00 [pubmed] -PHST- 2012/04/01 00:01 [medline] -AID - S2211-7458(12)00039-9 [pii] -AID - 10.1016/j.iccl.2012.02.003 [doi] -PST - ppublish -SO - Interv Cardiol Clin. 2012 Apr;1(2):251-258. doi: 10.1016/j.iccl.2012.02.003. Epub - 2012 Apr 10. - -PMID- 17198039 -OWN - NLM -STAT- MEDLINE -DCOM- 20070330 -LR - 20191110 -IS - 0887-9303 (Print) -IS - 0887-9303 (Linking) -VI - 30 -IP - 1 -DP - 2007 Jan-Mar -TI - Cardiac cell therapy: a treatment option for cardiomyopathy. -PG - 74-80 -AB - Cardiomyopathy is a common clinical disorder affecting the heart muscle. This - disease process frequently leads to congestive heart failure and will often - progress to end-stage heart failure. Present standard of care treatment options - for cardiomyopathy include medical management, lifestyle changes, and surgical - procedures including left ventricular assist devices as a destiny therapy or - bridging to heart transplantation. Even despite advances in drug therapy, - mechanical assist devices, and organ transplantation, more than half of the - persons with cardiomyopathy will die within 5 years of diagnosis. Small - uncontrolled clinical trials have demonstrated cardiac stem cells as a treatment - option for cardiomyopathy. The theory for the individual or combined mechanism of - action for stem cells includes (1) transdifferentiation to blood vessels or - myocardium, (2) fusion with the native dysfunctional myocytes to augment - function, and (3) homing that may be a systemic or panacrine response for - recruiting other cells, and growth factors to help improve oxygen delivery and - myocardial function. The field of cardiac cell therapy is rapidly progressing to - gather more data with intermediate-size, double-blinded trials that will - demonstrate the safety and efficacy of cell therapy. -FAU - Shepler, Sherrill A -AU - Shepler SA -AD - University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA. - sheplersa@upmc.edu -FAU - Patel, Amit N -AU - Patel AN -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Nurs Q -JT - Critical care nursing quarterly -JID - 8704517 -MH - Cardiomyopathies/complications/diagnosis/*therapy -MH - Cell Transplantation/adverse effects/*methods/nursing -MH - Clinical Trials as Topic -MH - Combined Modality Therapy -MH - Coronary Artery Bypass -MH - Critical Care/*methods -MH - Disease Progression -MH - Heart Failure/etiology -MH - Heart Transplantation -MH - Heart-Assist Devices -MH - Humans -MH - Life Style -MH - Male -MH - Middle Aged -MH - Muscle Cells/*transplantation -MH - Nurse's Role -MH - Patient Selection -MH - Stem Cell Transplantation/adverse effects/*methods/nursing -MH - Tomography, Emission-Computed, Single-Photon -RF - 30 -EDAT- 2007/01/02 09:00 -MHDA- 2007/03/31 09:00 -CRDT- 2007/01/02 09:00 -PHST- 2007/01/02 09:00 [pubmed] -PHST- 2007/03/31 09:00 [medline] -PHST- 2007/01/02 09:00 [entrez] -AID - 00002727-200701000-00009 [pii] -AID - 10.1097/00002727-200701000-00009 [doi] -PST - ppublish -SO - Crit Care Nurs Q. 2007 Jan-Mar;30(1):74-80. doi: - 10.1097/00002727-200701000-00009. - -PMID- 20640922 -OWN - NLM -STAT- MEDLINE -DCOM- 20101220 -LR - 20211020 -IS - 1563-258X (Electronic) -IS - 0043-5341 (Linking) -VI - 160 -IP - 11-12 -DP - 2010 Jun -TI - [Polypharmacy is of major concern in cardiology]. -PG - 264-269 -LID - 10.1007/s10354-010-0784-3 [doi] -AB - Quality improvement in cardiology over the past decade focused on management of - acute coronary syndrome with invasive and innovative medical therapies, - optimizing treatment of congestive heart failure and the development of repair - procedures in valvular heart disease. On the other hand cardiologist and the - attendant physicians are confronted with changes in the characteristics of - patients in the light of demographic facts. Comorbidity and polypharmacy raise - the need for clear concepts. Therapeutic and diagnostic tools of geriatric - medicine may help in that context. -FAU - Dovjak, Peter -AU - Dovjak P -AD - Abteilung für Akutgeriatrie/Remobilisation, Landeskrankenhaus Gmunden, Gmunden, - Austria. -FAU - Sommeregger, Ulrike -AU - Sommeregger U -AD - Abteilung für Akutgeriatrie, Krankenhaus Hietzing mit Neurologischem Zentrum - Rosenhügel, Wien, Austria. -FAU - Otto, Ronald -AU - Otto R -AD - Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Graz, - Austria. -FAU - Roller, Regina E -AU - Roller RE -AD - Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Graz, - Austria. -FAU - Böhmdorfer, Birgit -AU - Böhmdorfer B -AD - Anstaltsapotheke, Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, - Wien, Austria. -FAU - Iglseder, Bernhard -AU - Iglseder B -AD - Universitätsklinik für Geriatrie, Paracelsus Medizinische Privatuniversität, - Salzburg, Austria. -FAU - Benvenuti-Falger, Ursula -AU - Benvenuti-Falger U -AD - Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, - Austria. -FAU - Lechleitner, Monika -AU - Lechleitner M -AD - Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, - Austria. -FAU - Gosch, Markus -AU - Gosch M -AD - Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, - Austria. markus.gosch@tilak.at. -LA - ger -PT - Case Reports -PT - English Abstract -PT - Journal Article -PT - Review -TT - Polypharmazie in der Kardiologie - ein beachtliches Problem bei Synkopen, - QT-Zeit-Verlängerung, Bradykardie und Tachykardie. -PL - Austria -TA - Wien Med Wochenschr -JT - Wiener medizinische Wochenschrift (1946) -JID - 8708475 -RN - 0 (Cardiovascular Agents) -RN - 0 (Prescription Drugs) -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Bradycardia/*chemically induced -MH - Cardiovascular Agents/*adverse effects/*therapeutic use -MH - Drug Interactions -MH - Drug Therapy, Combination -MH - Frail Elderly -MH - Heart Diseases/*drug therapy -MH - Humans -MH - Long QT Syndrome/*chemically induced -MH - Prescription Drugs/*adverse effects/*therapeutic use -MH - Syncope/*chemically induced -MH - Tachycardia/*chemically induced -EDAT- 2010/07/20 06:00 -MHDA- 2010/12/21 06:00 -CRDT- 2010/07/20 06:00 -PHST- 2010/07/20 06:00 [entrez] -PHST- 2010/07/20 06:00 [pubmed] -PHST- 2010/12/21 06:00 [medline] -AID - 10.1007/s10354-010-0784-3 [pii] -AID - 10.1007/s10354-010-0784-3 [doi] -PST - ppublish -SO - Wien Med Wochenschr. 2010 Jun;160(11-12):264-269. doi: 10.1007/s10354-010-0784-3. - -PMID- 17205004 -OWN - NLM -STAT- MEDLINE -DCOM- 20070319 -LR - 20070125 -IS - 0090-3493 (Print) -IS - 0090-3493 (Linking) -VI - 35 -IP - 2 -DP - 2007 Feb -TI - Cardiac troponins in the intensive care unit: common causes of increased levels - and interpretation. -PG - 584-8 -AB - BACKGROUND AND OBJECTIVES: Clinical chemistry is an important component of the - diagnosis of many conditions, and advances in laboratory science have brought - many new diagnostic tools to the intensive care unit clinician, including new - biomarkers of cardiac injury like troponin T and I. Interpretation of these - clinical laboratory results requires knowledge of the performance of these tests. - SETTING AND PATIENTS: This article reviews the interpretation and performance of - diagnostic markers of myocardial injury in patients with diverse clinical - conditions of interest to critical care practitioners. CONCLUSIONS: Cardiac - troponin I and T, regulatory components of the contractile apparatus, are - sensitive indicators of myocardial injury and have become central to the - diagnosis of myocardial infarction. The troponins are also released in a number - of clinical situations in which thrombotic complications of coronary artery - disease and resultant acute myocardial infarction have not occurred. These - situations include conditions like pulmonary embolism, sepsis, myocarditis, and - acute stroke. Elevated troponins in these conditions are thought to emanate from - injured myocardial cells and, in most circumstances, have been associated with - adverse outcomes. Practitioners should be mindful of the wide spectrum of - diseases that may result in elevated troponin when interpreting these - measurements. -FAU - Fromm, Robert E Jr -AU - Fromm RE Jr -AD - Section of Cardiology, Baylor College of Medicine, Houston, TX, USA. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Med -JT - Critical care medicine -JID - 0355501 -RN - 0 (Troponin I) -RN - 0 (Troponin T) -SB - IM -MH - Heart Diseases/*blood/*diagnosis -MH - Humans -MH - *Intensive Care Units -MH - Troponin I/*blood -MH - Troponin T/*blood -RF - 54 -EDAT- 2007/01/06 09:00 -MHDA- 2007/03/21 09:00 -CRDT- 2007/01/06 09:00 -PHST- 2007/01/06 09:00 [pubmed] -PHST- 2007/03/21 09:00 [medline] -PHST- 2007/01/06 09:00 [entrez] -AID - 10.1097/01.CCM.0000254349.10953.BE [doi] -PST - ppublish -SO - Crit Care Med. 2007 Feb;35(2):584-8. doi: 10.1097/01.CCM.0000254349.10953.BE. - -PMID- 18046092 -OWN - NLM -STAT- MEDLINE -DCOM- 20080124 -LR - 20220331 -IS - 1527-5299 (Print) -IS - 1527-5299 (Linking) -VI - 13 -IP - 6 -DP - 2007 Nov-Dec -TI - The cholesterol paradox in heart failure. -PG - 336-41 -AB - Heart failure (HF) is a common and serious condition that is usually due to - coronary artery disease (CAD). Hypercholesterolemia is a major risk factor for - CAD but, paradoxically, patients with advanced HF often have low cholesterol, - which is associated with a poor prognosis. Cholesterol lowering with statins - reduces morbidity and mortality in patients with CAD who do not have HF and might - also have improved outcome in patients with HF had they not been excluded from - the reported trials. The results of large trials such as the Controlled - Rosuvastatin Multinational Study in Heart Failure (CORONA) and the Gruppo - Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico-Insufficienza - Cardiaca (GISSI-HF) study addressing the effects of rosuvastatin in HF are keenly - awaited. In addition to cholesterol lowering, statins have other biologic effects - that might be responsible for some of their favorable effects. This article - examines this cholesterol paradox and possible mechanisms. -FAU - Velavan, Periaswamy -AU - Velavan P -AD - Cardiothoracic Centre, Liverpool, UK. drvelavan@hotmail.com -FAU - Huan Loh, Poay -AU - Huan Loh P -FAU - Clark, Andrew -AU - Clark A -FAU - Cleland, John G F -AU - Cleland JG -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Congest Heart Fail -JT - Congestive heart failure (Greenwich, Conn.) -JID - 9714174 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Cholesterol/*blood -MH - Europe -MH - Heart Failure/*complications/mortality -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & - dosage/*therapeutic use -MH - Hypercholesterolemia/blood/complications/*drug therapy -MH - Randomized Controlled Trials as Topic -MH - Research Design -MH - Survival Analysis -RF - 60 -EDAT- 2007/11/30 09:00 -MHDA- 2008/01/25 09:00 -CRDT- 2007/11/30 09:00 -PHST- 2007/11/30 09:00 [pubmed] -PHST- 2008/01/25 09:00 [medline] -PHST- 2007/11/30 09:00 [entrez] -AID - 10.1111/j.1527-5299.2007.07211.x [doi] -PST - ppublish -SO - Congest Heart Fail. 2007 Nov-Dec;13(6):336-41. doi: - 10.1111/j.1527-5299.2007.07211.x. - -PMID- 27122710 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20160428 -LR - 20201001 -IS - 1011-6842 (Print) -IS - 1011-6842 (Linking) -VI - 29 -IP - 3 -DP - 2013 May -TI - Nitric Oxide Synthase 1 Adaptor Protein, an Emerging New Genetic Marker for QT - Prolongation and Sudden Cardiac Death. -PG - 217-25 -AB - Sudden cardiac death (SCD) is defined as sudden unexplained death due to cardiac - causes with an acute change in cardiovascular status within 1 hour of onset of - symptoms. Alternatively, in unwitnessed cases, SCD can also be defined as a - person last seen functionally normal 24 hours before being found dead. Despite - significant advances in understanding the pathophysiology of cardiovascular - diseases and the resultant improvement in resuscitation science, SCD remains a - major healthcare challenge worldwide. Although the most pronounced risk factor - for SCD is the presence of coronary artery disease in the setting of a depressed - left ventricular function, most deaths occur in the larger, lower-risk subgroups - where genetic variations and other conditions may be the precipitating factors in - triggering SCD. Recently, a common genetic variation in a neuronal nitric oxide - synthase regulator, nitric oxide synthase 1 adaptor protein (NOS1AP) also known - as carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (CAPON) - gene, has been identified as a new genetic marker in modulating QT interval - prolongation and SCD in general populations. Animal study revealed that NOS1AP is - expressed in the heart and interacts with NOS1-NO pathways to modulate cardiac - repolarization via suppressing the sarcolemmal L-type calcium current and - enhancing the IKr current. This important genetic implication was soon replicated - in other racial/ethnic populations and extended to a variety of clinical settings - including diabetes mellitus, coronary artery disease, myocardial infarction, and - congenital or drug-induced long QT syndrome. The purpose of this review aims to - provide up-to-date information about the emerging new genetic marker, NOS1AP, in - relation to QT prolongation and SCD. KEY WORDS: NOS1AP; QT interval; Sudden - cardiac death. -FAU - Chang, Kuan-Cheng -AU - Chang KC -AD - Division of Cardiology, Department of Medicine, China Medical University - Hospital; ; Graduate Institute of Clinical Medical Science, China Medical - University, Taichung, Taiwan; -FAU - Sasano, Tetsuo -AU - Sasano T -AD - Department of Biofunctional Informatics, Tokyo Medical and Dental University, - Tokyo, Japan; -FAU - Wang, Yu-Chen -AU - Wang YC -AD - Division of Cardiology, Department of Medicine, China Medical University - Hospital; ; Graduate Institute of Clinical Medical Science, China Medical - University, Taichung, Taiwan; -FAU - Huang, Shoei K Stephen -AU - Huang SK -AD - Section of Cardiac Electrophysiology and Pacing, Scott & White Healthcare, Texas - A & M University College of Medicine, Temple, TX, USA. -LA - eng -PT - Journal Article -PT - Review -PL - China (Republic : 1949- ) -TA - Acta Cardiol Sin -JT - Acta Cardiologica Sinica -JID - 101687085 -PMC - PMC4804833 -EDAT- 2013/05/01 00:00 -MHDA- 2013/05/01 00:01 -PMCR- 2013/05/01 -CRDT- 2016/04/29 06:00 -PHST- 2016/04/29 06:00 [entrez] -PHST- 2013/05/01 00:00 [pubmed] -PHST- 2013/05/01 00:01 [medline] -PHST- 2013/05/01 00:00 [pmc-release] -PST - ppublish -SO - Acta Cardiol Sin. 2013 May;29(3):217-25. - -PMID- 23528671 -OWN - NLM -STAT- MEDLINE -DCOM- 20140328 -LR - 20220331 -IS - 1878-1780 (Electronic) -IS - 1262-3636 (Linking) -VI - 39 -IP - 3 -DP - 2013 May -TI - Metformin revisited: a critical review of the benefit-risk balance in at-risk - patients with type 2 diabetes. -PG - 179-90 -LID - S1262-3636(13)00041-4 [pii] -LID - 10.1016/j.diabet.2013.02.006 [doi] -AB - Metformin is unanimously considered a first-line glucose-lowering agent. - Theoretically, however, it cannot be prescribed in a large proportion of patients - with type 2 diabetes because of numerous contraindications that could lead to an - increased risk of lactic acidosis. Various observational data from real-life have - shown that many diabetic patients considered to be at risk still receive - metformin and often without appropriate dose adjustment, yet apparently with no - harm done and particularly no increased risk of lactic acidosis. More - interestingly, recent data have suggested that type 2 diabetes patients - considered at risk because of the presence of traditional contraindications may - still derive benefit from metformin therapy with reductions in morbidity and - mortality compared with other glucose-lowering agents, especially sulphonylureas. - The present review analyzes the benefit-risk balance of metformin therapy in - special populations, namely, patients with stable coronary artery disease, acute - coronary syndrome or myocardial infarction, congestive heart failure, renal - impairment or chronic kidney disease, hepatic dysfunction and chronic respiratory - insufficiency, all conditions that could in theory increase the risk of lactic - acidosis. Special attention is also paid to elderly patients with type 2 - diabetes, a population that is growing rapidly, as older patients can accumulate - several comorbidities classically considered contraindications to the use of - metformin. A review of the recent scientific literature suggests that - reassessment of the contraindications of metformin is now urgently needed to - prevent physicians from prescribing the most popular glucose-lowering therapy in - everyday clinical practice outside of the official recommendations. -CI - Copyright © 2013 Elsevier Masson SAS. All rights reserved. -FAU - Scheen, A J -AU - Scheen AJ -AD - Division of Diabetes, Nutrition and Metabolic Disorders and Division of Clinical - Pharmacology, Department of Medicine, CHU Sart-Tilman (B35), University of Liège, - 4000 Liège, Belgium. andre.scheen@chu.ulg.ac.be -FAU - Paquot, N -AU - Paquot N -LA - eng -PT - Journal Article -PT - Review -DEP - 20130323 -PL - France -TA - Diabetes Metab -JT - Diabetes & metabolism -JID - 9607599 -RN - 0 (Hypoglycemic Agents) -RN - 9100L32L2N (Metformin) -SB - IM -CIN - Diabetes Metab. 2013 Sep;39(4):375-6. doi: 10.1016/j.diabet.2013.04.004. PMID: - 23871503 -MH - Contraindications -MH - Diabetes Mellitus, Type 2/*drug therapy/metabolism -MH - Humans -MH - Hypoglycemic Agents/adverse effects/*therapeutic use -MH - Metformin/adverse effects/*therapeutic use -EDAT- 2013/03/27 06:00 -MHDA- 2014/03/29 06:00 -CRDT- 2013/03/27 06:00 -PHST- 2013/02/08 00:00 [received] -PHST- 2013/02/12 00:00 [accepted] -PHST- 2013/03/27 06:00 [entrez] -PHST- 2013/03/27 06:00 [pubmed] -PHST- 2014/03/29 06:00 [medline] -AID - S1262-3636(13)00041-4 [pii] -AID - 10.1016/j.diabet.2013.02.006 [doi] -PST - ppublish -SO - Diabetes Metab. 2013 May;39(3):179-90. doi: 10.1016/j.diabet.2013.02.006. Epub - 2013 Mar 23. - -PMID- 22368166 -OWN - NLM -STAT- MEDLINE -DCOM- 20130201 -LR - 20220331 -IS - 1940-5596 (Electronic) -IS - 1089-2532 (Print) -IS - 1089-2532 (Linking) -VI - 16 -IP - 3 -DP - 2012 Sep -TI - Myocardial ischemia reperfusion injury: from basic science to clinical bedside. -PG - 123-32 -LID - 10.1177/1089253211436350 [doi] -AB - Myocardial ischemia reperfusion injury contributes to adverse cardiovascular - outcomes after myocardial ischemia, cardiac surgery or circulatory arrest. - Primarily, no blood flow to the heart causes an imbalance between oxygen demand - and supply, named ischemia (from the Greek isch, restriction; and haema, blood), - resulting in damage or dysfunction of the cardiac tissue. Instinctively, early - and fast restoration of blood flow has been established to be the treatment of - choice to prevent further tissue injury. Indeed, the use of thrombolytic therapy - or primary percutaneous coronary intervention is the most effective strategy for - reducing the size of a myocardial infarct and improving the clinical outcome. - Unfortunately, restoring blood flow to the ischemic myocardium, named - reperfusion, can also induce injury. This phenomenon was therefore termed - myocardial ischemia reperfusion injury. Subsequent studies in animal models of - acute myocardial infarction suggest that myocardial ischemia reperfusion injury - accounts for up to 50% of the final size of a myocardial infarct. Consequently, - many researchers aim to understand the underlying molecular mechanism of - myocardial ischemia reperfusion injury to find therapeutic strategies ultimately - reducing the final infarct size. Despite the identification of numerous - therapeutic strategies at the bench, many of them are just in the process of - being translated to bedside. The current review discusses the most striking basic - science findings made during the past decades that are currently under clinical - evaluation, with the ultimate goal to treat patients who are suffering from - myocardial ischemia reperfusion-associated tissue injury. -FAU - Frank, Anja -AU - Frank A -AD - University of Colorado Denver, Aurora, CO 80045, USA. -FAU - Bonney, Megan -AU - Bonney M -FAU - Bonney, Stephanie -AU - Bonney S -FAU - Weitzel, Lindsay -AU - Weitzel L -FAU - Koeppen, Michael -AU - Koeppen M -FAU - Eckle, Tobias -AU - Eckle T -LA - eng -GR - K08 HL102267/HL/NHLBI NIH HHS/United States -GR - K08HL102267/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120223 -PL - United States -TA - Semin Cardiothorac Vasc Anesth -JT - Seminars in cardiothoracic and vascular anesthesia -JID - 9807630 -RN - 0 (Fibrinolytic Agents) -SB - IM -MH - Animals -MH - Disease Models, Animal -MH - Fibrinolytic Agents/therapeutic use -MH - Humans -MH - Myocardial Infarction/*physiopathology/therapy -MH - Myocardial Ischemia/*physiopathology/therapy -MH - Myocardial Reperfusion Injury/*physiopathology/therapy -MH - Percutaneous Coronary Intervention -PMC - PMC3457795 -MID - NIHMS375990 -EDAT- 2012/03/01 06:00 -MHDA- 2013/02/05 06:00 -PMCR- 2012/09/25 -CRDT- 2012/02/28 06:00 -PHST- 2012/02/28 06:00 [entrez] -PHST- 2012/03/01 06:00 [pubmed] -PHST- 2013/02/05 06:00 [medline] -PHST- 2012/09/25 00:00 [pmc-release] -AID - 1089253211436350 [pii] -AID - 10.1177/1089253211436350 [doi] -PST - ppublish -SO - Semin Cardiothorac Vasc Anesth. 2012 Sep;16(3):123-32. doi: - 10.1177/1089253211436350. Epub 2012 Feb 23. - -PMID- 17516166 -OWN - NLM -STAT- MEDLINE -DCOM- 20071108 -LR - 20181113 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 12 -IP - 3-4 -DP - 2007 Dec -TI - Cardioprotective actions of peptide hormones in myocardial ischemia. -PG - 279-91 -AB - The myocardium represents a major source of several families of peptide hormones - under normal physiological conditions and the plasma concentrations of many of - these "cardiac peptides" (or related pro-peptide fragments) are substantially - augmented in many cardiac disease states. In addition to well-characterised - endocrine functions of several of the cardiac peptides, pleiotropic functions - within the myocardium and the coronary vasculature represent a significant aspect - of their actions in health and disease. Here, we focus specifically on the - cardioprotective roles of four major peptide families in myocardial ischemia and - reperfusion: adrenomedullin, kinins, natriuretic peptides and the urocortins. The - patterns of early release of all these peptides are consistent with roles as - autacoid cardioprotective mediators. Clinical and experimental research indicates - the early release and upregulation of many of these peptides by acute ischemia - and there is a convincing body of evidence showing that exogenously administered - adrenomedullin, bradykinin, ANP, BNP, CNP and urocortins are all markedly - protective against experimental myocardial ischemia-reperfusion injury through a - conserved series of cytoprotective signal transduction pathways. Intriguingly, - all the peptides examined so far have the potential to salvage against infarction - when administered specifically during early reperfusion. Thus, the myocardial - secretion of peptide hormones likely represents an early protective response to - ischemia. Further work is required to explore the potential therapeutic - manipulation of these peptides in acute coronary syndromes and their promise as - biomarkers of acute myocardial ischemia. -FAU - Burley, Dwaine S -AU - Burley DS -AD - Department of Basic Sciences, The Royal Veterinary College, University of London, - Royal College Street, London, UK. -FAU - Hamid, Shabaz A -AU - Hamid SA -FAU - Baxter, Gary F -AU - Baxter GF -LA - eng -GR - Wellcome Trust/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Natriuretic Peptides) -RN - 0 (Peptide Hormones) -RN - 148498-78-6 (Adrenomedullin) -RN - S8TIM42R2W (Bradykinin) -SB - IM -MH - Adrenomedullin -MH - Bradykinin -MH - Humans -MH - Myocardial Infarction/complications -MH - Myocardial Ischemia/physiopathology/*prevention & control -MH - *Myocardial Reperfusion -MH - *Myocardium -MH - Natriuretic Peptides -MH - Peptide Hormones/*physiology -MH - Signal Transduction -RF - 129 -EDAT- 2007/05/23 09:00 -MHDA- 2007/11/09 09:00 -CRDT- 2007/05/23 09:00 -PHST- 2007/05/23 09:00 [pubmed] -PHST- 2007/11/09 09:00 [medline] -PHST- 2007/05/23 09:00 [entrez] -AID - 10.1007/s10741-007-9029-y [doi] -PST - ppublish -SO - Heart Fail Rev. 2007 Dec;12(3-4):279-91. doi: 10.1007/s10741-007-9029-y. - -PMID- 18316000 -OWN - NLM -STAT- MEDLINE -DCOM- 20080424 -LR - 20231024 -IS - 0025-6196 (Print) -IS - 0025-6196 (Linking) -VI - 83 -IP - 3 -DP - 2008 Mar -TI - Omega-3 fatty acids for cardioprotection. -PG - 324-32 -LID - 10.4065/83.3.324 [doi] -AB - The most compelling evidence for the cardiovascular benefit provided by omega-3 - fatty acids comes from 3 large controlled trials of 32,000 participants - randomized to receive omega-3 fatty acid supplements containing docosahexaenoic - acid (DHA) and eicosapentaenoic acid (EPA) or to act as controls. These trials - showed reductions in cardiovascular events of 19% to 45%. These findings suggest - that intake of omega-3 fatty acids, whether from dietary sources or fish oil - supplements, should be increased, especially in those with or at risk for - coronary artery disease. Patients should consume both DHA and EPA. The target DHA - and EPA consumption levels are about 1 g/d for those with known coronary artery - disease and at least 500 mg/d for those without disease. Patients with - hypertriglyceridemia benefit from treatment with 3 to 4 g/d of DHA and EPA, a - dosage that lowers triglyceride levels by 20% to 50%. Although 2 meals of oily - fish per week can provide 400 to 500 mg/d of DHA and EPA, secondary prevention - patients and those with hypertriglyceridemia must use fish oil supplements if - they are to reach 1 g/d and 3 to 4 g/d of DHA and EPA, respectively. Combination - therapy with omega-3 fatty acids and a statin is a safe and effective way to - improve lipid levels and cardiovascular prognosis beyond the benefits provided by - statin therapy alone. Blood DHA and EPA levels could one day be used to identify - patients with deficient levels and to individualize therapeutic recommendations. -FAU - Lee, John H -AU - Lee JH -AD - Mid America Heart Institute and University of Missouri-Kansas City, 4330 Wornall - Road, Kansas City, MO 64111, USA. -FAU - O'Keefe, James H -AU - O'Keefe JH -FAU - Lavie, Carl J -AU - Lavie CJ -FAU - Marchioli, Roberto -AU - Marchioli R -FAU - Harris, William S -AU - Harris WS -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Mayo Clin Proc -JT - Mayo Clinic proceedings -JID - 0405543 -RN - 0 (Fatty Acids, Omega-3) -SB - IM -EIN - Mayo Clin Proc. 2008 Jun;83(6):730 -CIN - Mayo Clin Proc. 2008 Jun;83(6):723; author reply 724-5. PMID: 18533090 -CIN - Mayo Clin Proc. 2008 Jun;83(6):724; author reply 724-5. PMID: 18536132 -MH - Cardiovascular Diseases/*prevention & control -MH - Fatty Acids, Omega-3/*therapeutic use -MH - Humans -MH - Primary Prevention/*methods -MH - Treatment Outcome -RF - 59 -EDAT- 2008/03/05 09:00 -MHDA- 2008/04/25 09:00 -CRDT- 2008/03/05 09:00 -PHST- 2008/03/05 09:00 [pubmed] -PHST- 2008/04/25 09:00 [medline] -PHST- 2008/03/05 09:00 [entrez] -AID - S0025-6196(11)60866-5 [pii] -AID - 10.4065/83.3.324 [doi] -PST - ppublish -SO - Mayo Clin Proc. 2008 Mar;83(3):324-32. doi: 10.4065/83.3.324. - -PMID- 21919242 -OWN - NLM -STAT- MEDLINE -DCOM- 20111013 -LR - 20110915 -IS - 1682-8658 (Print) -IS - 1682-8658 (Linking) -IP - 5 -DP - 2011 -TI - [Cardiovascular pathology associated with digestive system diseases]. -PG - 69-74 -AB - With age, a person has "accumulation" of diseases. In patients of older age - groups occurs simultaneously for at least 3-4 diseases. Assigning patients with - ischemic heart disease (IHD), the physician takes into account the presence of - concomitant diseases, especially diseases of the gastrointestinal tract, since - the defeat of the stomach, liver, intestine may influence not only on the - clinical course of heart disease, but also to change the pharmacokinetics of - cardiac drugs. All groups of drugs used in treating coronary artery disease, have - different effects on the digestive organs. This can be a positive influence. For - example, the use of beta-blockers and nitrates for prevention of bleeding from - esophageal varices at cirrhosis of the liver, calcium antagonists in achalasia - cardia. It is well known, and the negative effect of cardiac drugs: erosive and - ulcerative lesions of the stomach with aspirin use, increasing manifestations of - GERD in patients receiving calcium antagonists (dihydropyridines group). In this - regard, we need for rational pharmacotherapy. -FAU - Lazebnik, L B -AU - Lazebnik LB -FAU - Komissarenko, I A -AU - Komissarenko IA -FAU - Mikheeva, O M -AU - Mikheeva OM -LA - rus -PT - English Abstract -PT - Journal Article -PT - Review -PL - Russia (Federation) -TA - Eksp Klin Gastroenterol -JT - Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical - gastroenterology -JID - 101144944 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Calcium Channel Blockers) -SB - IM -MH - Adrenergic beta-Antagonists/adverse effects/pharmacokinetics/therapeutic use -MH - Calcium Channel Blockers/adverse effects/pharmacokinetics/therapeutic use -MH - Digestive System Diseases/*complications/drug therapy/metabolism -MH - Humans -MH - Myocardial Ischemia/*complications/drug therapy/metabolism -EDAT- 2011/09/16 06:00 -MHDA- 2011/10/14 06:00 -CRDT- 2011/09/16 06:00 -PHST- 2011/09/16 06:00 [entrez] -PHST- 2011/09/16 06:00 [pubmed] -PHST- 2011/10/14 06:00 [medline] -PST - ppublish -SO - Eksp Klin Gastroenterol. 2011;(5):69-74. - -PMID- 17512599 -OWN - NLM -STAT- MEDLINE -DCOM- 20090602 -LR - 20220321 -IS - 1879-016X (Electronic) -IS - 0163-7258 (Linking) -VI - 114 -IP - 3 -DP - 2007 Jun -TI - Effects of exercise training on the cardiovascular system: pharmacological - approaches. -PG - 307-17 -AB - Physical exercise promotes beneficial health effects by preventing or reducing - the deleterious effects of pathological conditions, such as arterial - hypertension, coronary artery disease, atherosclerosis, diabetes mellitus, - osteoporosis, Parkinson's disease, and Alzheimer disease. Human movement studies - are becoming an emerging science in the epidemiological area and public health. A - great number of studies have shown that exercise training, in general, reduces - sympathetic activity and/or increases parasympathetic tonus either in human or - laboratory animals. Alterations in autonomic nervous system have been correlated - with reduction in heart rate (resting bradycardia) and blood pressure, either in - normotensive or hypertensive subjects. However, the underlying mechanisms by - which physical exercise produce bradycardia and reduces blood pressure has not - been fully understood. Pharmacological studies have particularly contributed to - the comprehension of the role of receptor and transduction signaling pathways on - the heart and blood vessels in response to exercise training. This review - summarizes and examines the data from studies using animal models and human to - determine the effect of exercise training on the cardiovascular system. -FAU - Zanesco, Angelina -AU - Zanesco A -AD - Department of Physical Education, Institute of Bioscience, University of Sao - Paulo State (UNESP), Rio Claro (SP), Cep: 13506-900, Brazil. azanesco@rc.unesp.br -FAU - Antunes, Edson -AU - Antunes E -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20070421 -PL - England -TA - Pharmacol Ther -JT - Pharmacology & therapeutics -JID - 7905840 -RN - 0 (Receptors, Adrenergic) -RN - 0 (Receptors, Muscarinic) -RN - 0 (Receptors, Purinergic P1) -SB - IM -MH - Animals -MH - *Cardiovascular Physiological Phenomena/drug effects -MH - Erectile Dysfunction/physiopathology -MH - Humans -MH - Male -MH - Muscle, Smooth, Vascular/physiology -MH - Pharmacology -MH - Physical Conditioning, Animal/physiology -MH - Physical Fitness/*physiology -MH - Receptors, Adrenergic/physiology -MH - Receptors, Muscarinic/physiology -MH - Receptors, Purinergic P1/physiology -RF - 124 -EDAT- 2007/05/22 09:00 -MHDA- 2009/06/03 09:00 -CRDT- 2007/05/22 09:00 -PHST- 2007/03/28 00:00 [received] -PHST- 2007/03/28 00:00 [accepted] -PHST- 2007/05/22 09:00 [pubmed] -PHST- 2009/06/03 09:00 [medline] -PHST- 2007/05/22 09:00 [entrez] -AID - S0163-7258(07)00072-1 [pii] -AID - 10.1016/j.pharmthera.2007.03.010 [doi] -PST - ppublish -SO - Pharmacol Ther. 2007 Jun;114(3):307-17. doi: 10.1016/j.pharmthera.2007.03.010. - Epub 2007 Apr 21. - -PMID- 17479031 -OWN - NLM -STAT- MEDLINE -DCOM- 20070710 -LR - 20070504 -IS - 0952-7907 (Print) -IS - 0952-7907 (Linking) -VI - 20 -IP - 3 -DP - 2007 Jun -TI - Perioperative medical management of ischemic heart disease in patients undergoing - noncardiac surgery. -PG - 254-60 -AB - PURPOSE OF REVIEW: Cardiovascular disease is the leading cause of death after - anesthesia and surgery. The preoperative identification of patients with - underlying coronary artery disease is important to initiate appropriate treatment - strategies in order to reduce the risk of perioperative complications. The - current review will discuss new insights in the field of perioperative medicine - that can be applied to clinical practice or stimulate further investigation. - RECENT FINDINGS: Recent findings in the past year have developed preoperative - risk stratification in terms of simplicity, safety, accuracy and - cost-effectiveness. Natriuretic peptides have been demonstrated to be promising - new preoperative risk markers. Although recommended in high-risk patients, - noninvasive cardiac stress testing may be safely omitted in patients at - intermediate risk. The antiischemic properties of beta-blockers have been well - described. In clinical practice, however, adequate beta-blocker dosage, tight - perioperative heart rate control and continuation of beta-blockers after surgery - may also be important factors. Statins have emerged as promising drugs with - perioperative cardioprotective properties. Before recommending routine - administration of statin therapy, however, more clinical trials are needed. - SUMMARY: New perceptions in perioperative medical management and novel - developments in surgical and anesthesiology techniques continue to improve the - cardiovascular outcome of patents undergoing major noncardiac surgery. -FAU - Feringa, Harm H H -AU - Feringa HH -AD - Department of Cardiology, Leiden University Medical Center, Leiden, The - Netherlands. -FAU - Bax, Jeroen J -AU - Bax JJ -FAU - Poldermans, Don -AU - Poldermans D -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Anaesthesiol -JT - Current opinion in anaesthesiology -JID - 8813436 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Cardiotonic Agents) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Anesthesia -MH - Cardiotonic Agents/therapeutic use -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Myocardial Ischemia/*complications/*physiopathology -MH - *Perioperative Care -MH - Risk Assessment -MH - *Surgical Procedures, Operative -RF - 67 -EDAT- 2007/05/05 09:00 -MHDA- 2007/07/11 09:00 -CRDT- 2007/05/05 09:00 -PHST- 2007/05/05 09:00 [pubmed] -PHST- 2007/07/11 09:00 [medline] -PHST- 2007/05/05 09:00 [entrez] -AID - 00001503-200706000-00019 [pii] -AID - 10.1097/ACO.0b013e3280c60c50 [doi] -PST - ppublish -SO - Curr Opin Anaesthesiol. 2007 Jun;20(3):254-60. doi: 10.1097/ACO.0b013e3280c60c50. - -PMID- 21411208 -OWN - NLM -STAT- MEDLINE -DCOM- 20110729 -LR - 20110401 -IS - 1579-2242 (Electronic) -IS - 0300-8932 (Linking) -VI - 64 -IP - 4 -DP - 2011 Apr -TI - [Neurology and cardiology: points of contact]. -PG - 319-27 -LID - 10.1016/j.recesp.2010.12.004 [doi] -AB - Strokes resulting from cardiac diseases, and cardiac abnormalities associated - with neuromuscular disorders are examples of the many points of contact between - neurology and cardiology. Approximately 20-30% of strokes are related to cardiac - diseases, including atrial fibrillation, congestive heart failure, bacterial - endocarditis, rheumatic and nonrheumatic valvular diseases, acute myocardial - infarction with left ventricular thrombus, and cardiomyopathies associated with - muscular dystrophies, among others. Strokes can also occur in the setting of - cardiac interventions such as cardiac catheterization and coronary artery bypass - procedures. Treatment to prevent recurrent stroke in any of these settings - depends on the underlying etiology. Whereas anticoagulation with vitamin K - antagonists is proven to be superior to acetylsalicylic acid for stroke - prevention in atrial fibrillation, the superiority of anticoagulants has not been - conclusively established for stroke associated with congestive heart failure and - is contraindicated in those with infective endocarditis. Ongoing trials are - evaluating management strategies in patients with atrial level shunts due to - patent foramen ovale. Cardiomyopathies and conduction abnormalities are part of - the spectrum of many neuromuscular disorders including mitochondrial disorders - and muscular dystrophies. Cardiologists and neurologists share responsibility for - caring for patients with or at risk for cardiogenic strokes, and for screening - and managing the heart disease associated with neuromuscular disorders. -CI - Copyright © 2010 Sociedad Española de Cardiología. Published by Elsevier Espana. - All rights reserved. -FAU - Goldstein, Larry B -AU - Goldstein LB -AD - Division of Neurology, Department of Medicine, Duke Stroke Center, Duke - University Medical Center, Durham, North Carolina, Estados Unidos. - golds004@mc.duke.edu -FAU - El Husseini, Nada -AU - El Husseini N -LA - spa -PT - English Abstract -PT - Journal Article -PT - Review -TT - Neurología y cardiología: puntos de contacto. -DEP - 20110315 -PL - Spain -TA - Rev Esp Cardiol -JT - Revista espanola de cardiologia -JID - 0404277 -SB - IM -MH - Cardiology/*trends -MH - Cerebrovascular Disorders/complications -MH - Heart Diseases/*complications/*etiology -MH - Humans -MH - Nervous System Diseases/*complications/*etiology -MH - Neurology/*trends -MH - Neuromuscular Diseases/complications -MH - Stroke/*etiology -EDAT- 2011/03/18 06:00 -MHDA- 2011/07/30 06:00 -CRDT- 2011/03/18 06:00 -PHST- 2010/12/10 00:00 [received] -PHST- 2010/12/10 00:00 [accepted] -PHST- 2011/03/18 06:00 [entrez] -PHST- 2011/03/18 06:00 [pubmed] -PHST- 2011/07/30 06:00 [medline] -AID - S0300-8932(11)00194-1 [pii] -AID - 10.1016/j.recesp.2010.12.004 [doi] -PST - ppublish -SO - Rev Esp Cardiol. 2011 Apr;64(4):319-27. doi: 10.1016/j.recesp.2010.12.004. Epub - 2011 Mar 15. - -PMID- 20977421 -OWN - NLM -STAT- MEDLINE -DCOM- 20110502 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 16 -IP - 32 -DP - 2010 -TI - Glucocorticoids and the cardiovascular system: state of the art. -PG - 3574-85 -AB - Glucocorticoids (GC) are drugs commonly used, by approximately 1% of the total - adult population as anti-inflammatory and immunosuppressive therapies for asthma, - inflammatory bowel disease, dermatological, ophthalmic, neurological, and - rheumatic autoimmune diseases. Supporting evidence exists of GC use in both - immune mediated and non-immune mediated heart disease. The molecular mechanisms - by which GC induces immune-modulation and direct cardioprotection, are complex - and not fully understood. We review herein, the current knowledge of GC use in - various immune-mediated or non-immune mediated cardiovascular conditions. GC have - been investigated in autoimmune, inflammatory and idiopathic heart diseases such - as atrio-ventricular conduction abnormalities, rheumatic fever, myocarditis, - dilated cardiomyopathy, Churg-Strauss syndrome, Kawasaki disease and sarcoidosis. - GC therapy has been studied in non-autoimmune and non-inflammatory indications - such as acute myocardial infarction, angina, postpericardiotomy syndrome and - other pericardial diseases, endocarditis and cardiac amyloidosis, as well as in - invasive cardiology, coronary interventions, and cardiopulmonary-bypass surgery. - Despite GC's role as natural, physiologic regulators of the immune system, - cardiovascular adverse outcomes may occur. Some of the well-known side effects of - GC therapy involve bone, metabolic, and cardiovascular systems and include - osteoporosis, fractures, dyslipidemia, diabetes, obesity, and hypertension. -FAU - Nussinovitch, Udi -AU - Nussinovitch U -AD - Department of Internal Medicine B, Sheba Medical Center, Tel-Hashomer, Tel-Aviv - University, Israel. -FAU - de Carvalho, Jozélio Freire -AU - de Carvalho JF -FAU - Pereira, Rosa Maria R -AU - Pereira RM -FAU - Shoenfeld, Yehuda -AU - Shoenfeld Y -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Glucocorticoids) -SB - IM -MH - Cardiovascular Diseases/drug therapy -MH - Cardiovascular System/*drug effects -MH - Glucocorticoids/adverse effects/*pharmacology/therapeutic use -MH - Humans -EDAT- 2010/10/28 06:00 -MHDA- 2011/05/03 06:00 -CRDT- 2010/10/28 06:00 -PHST- 2010/07/19 00:00 [received] -PHST- 2010/09/24 00:00 [accepted] -PHST- 2010/10/28 06:00 [entrez] -PHST- 2010/10/28 06:00 [pubmed] -PHST- 2011/05/03 06:00 [medline] -AID - BSP/CPD/E-Pub/000246 [pii] -AID - 10.2174/138161210793797870 [doi] -PST - ppublish -SO - Curr Pharm Des. 2010;16(32):3574-85. doi: 10.2174/138161210793797870. - -PMID- 17215796 -OWN - NLM -STAT- MEDLINE -DCOM- 20070406 -LR - 20130520 -IS - 0031-0808 (Print) -IS - 0031-0808 (Linking) -VI - 48 -IP - 4 -DP - 2006 Dec -TI - Updated review (2006) on Helicobacter pylori as a potential target for the - therapy of ischemic heart disease. -PG - 241-6 -AB - Despite knowledge about the classical risk factors for ischemic heart disease - (IHD) has increased, all the differences in morbidity as well as mortality from - this disease cannot be fully explained. Hence the importance of looking for other - causal mechanisms. Numerous infectious agents have been linked to IHD and among - these also Helicobacter pylori (H. pylori). However, a number of studies have - reported conflicting RESULTS: The present review attempts to highlight on the - update pertaining a potential etiologic role of H. pylori infection in the - pathogenesis of IHD. Some new evidences have emerged in the last years in - literature. While epidemiological approach seems to confirm previous - uncertainties (hypothetical role of the bacterium in the acute phase), - experiments have demonstrated the presence of bacterial DNA in the plaque. - Furthermore, the most encouraging evidence of a possible association emerges from - an intervention small trial showing a significant reduction of coronary events - after H. pylori eradication. Because IHD is the outcome of a multiciplity of - factors, many of which with only a limited individual effect, complete - understanding of causation is difficult. It may be possible to identify some - factors, such as H. pylori, the effects of which are large enough to be potential - target for prevention. This is of major public health importance, since the - eradication of the infection is easy and certainly much less expensive than - long-term treatment for other risk factors. Prospective population-based studies - and interventional trials, focusing on the advantage of the eradication of H. - pylori infection on the prevention or the reduction of recurrence in subjects - with IHD, should be performed in order to provide support of a causal - relationship. This represents a promising direction for future studies. -FAU - Pellicano, R -AU - Pellicano R -AD - Department of Gastro-Hepatology, Molinette Hospital, Via Chiabrera 34, 10126 - Turin, Italy. rinaldo_pellican@hotmail.com -FAU - Peyre, S -AU - Peyre S -FAU - Astegiano, M -AU - Astegiano M -FAU - Oliaro, E -AU - Oliaro E -FAU - Fagoonee, S -AU - Fagoonee S -FAU - Rizzetto, M -AU - Rizzetto M -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Panminerva Med -JT - Panminerva medica -JID - 0421110 -RN - 0 (Anti-Bacterial Agents) -SB - IM -MH - Anti-Bacterial Agents/*therapeutic use -MH - Helicobacter Infections/*complications/*drug therapy -MH - *Helicobacter pylori -MH - Humans -MH - Myocardial Ischemia/*microbiology -RF - 47 -EDAT- 2007/01/12 09:00 -MHDA- 2007/04/07 09:00 -CRDT- 2007/01/12 09:00 -PHST- 2007/01/12 09:00 [pubmed] -PHST- 2007/04/07 09:00 [medline] -PHST- 2007/01/12 09:00 [entrez] -PST - ppublish -SO - Panminerva Med. 2006 Dec;48(4):241-6. - -PMID- 20542819 -OWN - NLM -STAT- MEDLINE -DCOM- 20100927 -LR - 20240910 -IS - 1969-6213 (Electronic) -IS - 1774-024X (Linking) -VI - 6 Suppl G -DP - 2010 May -TI - Integrated anatomy and viability assessment PET-CT. -PG - G132-7 -LID - EIJV6IGA18 [pii] -AB - Myocardial viability testing can identify patients with ischaemic heart disease - and left ventricular dysfunction who can potentially benefit from both improved - cardiac function and prognosis after revascularisation. Evaluation of myocardial - glucose metabolism by 18F-fluorodeoxyglucose (FDG) positron emission tomography - (PET) is considered the most sensitive tool to detect viability, and it predicts - functional recovery as well as improved prognosis upon revascularisation. In - parallel with the improved availability of PET, scanners have been changed into - hybrid devices consisting of both multidetector computed tomography (CT) and PET - (PET-CT). The immediate benefit for viability imaging is the ability to merge the - coronary CT angiography images with FDG PET viability data. In addition, the - possibility to utilise CT for myocardial viability imaging, such as - delayed-enhancement imaging of myocardial infarction with acceptable radiation - dose has been intensely investigated. This review will describe the principles of - viability assessment by PET, and discuss the possibilities provided by hybrid - PET-CT in this setting. -FAU - Saraste, Antti -AU - Saraste A -AD - Turku PET Centre, University of Turku, Turku, Finland. -FAU - Ukkonen, Heikki -AU - Ukkonen H -FAU - Kajander, Sami -AU - Kajander S -FAU - Knuuti, Juhani -AU - Knuuti J -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - France -TA - EuroIntervention -JT - EuroIntervention : journal of EuroPCR in collaboration with the Working Group on - Interventional Cardiology of the European Society of Cardiology -JID - 101251040 -RN - 0 (Radiopharmaceuticals) -RN - 0Z5B2CJX4D (Fluorodeoxyglucose F18) -SB - IM -MH - Fluorodeoxyglucose F18 -MH - Heart Diseases/*diagnostic imaging/physiopathology/therapy -MH - Humans -MH - Image Interpretation, Computer-Assisted -MH - Myocardium/*pathology -MH - *Positron-Emission Tomography -MH - Predictive Value of Tests -MH - Radiopharmaceuticals -MH - Recovery of Function -MH - Tissue Survival -MH - *Tomography, X-Ray Computed -MH - Treatment Outcome -RF - 21 -EDAT- 2010/06/18 06:00 -MHDA- 2010/09/29 06:00 -CRDT- 2010/06/15 06:00 -PHST- 2010/06/15 06:00 [entrez] -PHST- 2010/06/18 06:00 [pubmed] -PHST- 2010/09/29 06:00 [medline] -AID - EIJV6IGA18 [pii] -PST - ppublish -SO - EuroIntervention. 2010 May;6 Suppl G:G132-7. - -PMID- 18700690 -OWN - NLM -STAT- MEDLINE -DCOM- 20080916 -LR - 20220331 -IS - 1128-3602 (Print) -IS - 1128-3602 (Linking) -VI - 12 -IP - 3 -DP - 2008 May-Jun -TI - Protective effect of lycopene in cardiovascular disease. -PG - 183-90 -AB - Coronary artery disease (CAD) represents the primary cause of death in Western - Countries with an high incidence on human health and community social costs. - Oxidative stress induced by reactive oxygen species (ROS) plays an important role - in the aetiology of this disease. In particular, the LDL-oxidization has a key - role in the pathogenesis of atherosclerosis and cardiovascular heart diseases - through the initiation of plaque formation process. Dietary phytochemical - products such antioxidant vitamins (A,C,E) and bioactive food components (alpha- - and beta-carotene) have shown an antioxidant effect in reducing both oxidative - markers stress and LDL-oxidization process. Scientifical evidences support the - beneficial roles of phytochemicals in the prevention of some chronic diseases. - Lycopene, an oxygenated carotenoid with great antioxidant properties, has shown - both in epidemiological studies and supplementation human trials a reduction of - cardiovascular risk. However, controlled clinical trials and dietary intervention - studies using well-defined subjects population haven't been provided a clear - evidence of lycopene in the prevention of cardiovascular diseases. The present - short review aims to evaluate the beneficial effect of lycopene in the prevention - of cardiovascular disease. -FAU - Riccioni, G -AU - Riccioni G -AD - Cardiology Unit, San Camillo de Lellis Hospital, Manfredonia, Foggia, Italy. - griccioni@hotmail.com -FAU - Mancini, B -AU - Mancini B -FAU - Di Ilio, E -AU - Di Ilio E -FAU - Bucciarelli, T -AU - Bucciarelli T -FAU - D'Orazio, N -AU - D'Orazio N -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Eur Rev Med Pharmacol Sci -JT - European review for medical and pharmacological sciences -JID - 9717360 -RN - 0 (Antioxidants) -RN - 36-88-4 (Carotenoids) -RN - SB0N2N0WV6 (Lycopene) -SB - IM -MH - Antioxidants/*administration & dosage -MH - Cardiovascular Diseases/epidemiology/etiology/*prevention & control -MH - Carotenoids/*administration & dosage/chemistry/pharmacology -MH - Dietary Supplements -MH - Humans -MH - Lycopene -MH - Oxidative Stress -RF - 80 -EDAT- 2008/08/15 09:00 -MHDA- 2008/09/17 09:00 -CRDT- 2008/08/15 09:00 -PHST- 2008/08/15 09:00 [pubmed] -PHST- 2008/09/17 09:00 [medline] -PHST- 2008/08/15 09:00 [entrez] -PST - ppublish -SO - Eur Rev Med Pharmacol Sci. 2008 May-Jun;12(3):183-90. - -PMID- 23731877 -OWN - NLM -STAT- MEDLINE -DCOM- 20140124 -LR - 20130604 -IS - 1878-1594 (Electronic) -IS - 1521-690X (Linking) -VI - 27 -IP - 2 -DP - 2013 Apr -TI - Impact of obesity on cardiovascular health. -PG - 147-56 -LID - S1521-690X(13)00018-3 [pii] -LID - 10.1016/j.beem.2013.01.004 [doi] -AB - This review examines the impact of obesity on cardiovascular health. We will - review first, relationship between obesity and hypertension. Second, we will - describe obesity-related subclinical abnormalities in cardiovascular function and - structure. Third, we will summarize evidence linking obesity to overt - cardiovascular disease including coronary artery disease, congestive heart - failure, stroke, arrhythmias and sudden cardiac death. Fourth, we will discuss - the potential mechanisms underlying increased cardiovascular risk in obese - subjects. Last, we will discuss contribution of sleep apnea to the link between - obesity and cardiovascular disease. Despite recent progress in understanding - epidemiologic and pathophysiological links between obesity and cardiovascular - disease, several issues remain to be addressed in the future studies. There is a - clear need to identify better markers of obesity-related subclinical - cardiovascular damage. Furthermore, we should improve identification of obese - subjects at highest cardiovascular risk. -CI - Copyright © 2013 Elsevier Ltd. All rights reserved. -FAU - Chrostowska, Marzena -AU - Chrostowska M -AD - Department of Hypertension and Diabetology, Medical University of Gdańsk, Gdańsk, - Poland. -FAU - Szyndler, Anna -AU - Szyndler A -FAU - Hoffmann, Michał -AU - Hoffmann M -FAU - Narkiewicz, Krzysztof -AU - Narkiewicz K -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130301 -PL - Netherlands -TA - Best Pract Res Clin Endocrinol Metab -JT - Best practice & research. Clinical endocrinology & metabolism -JID - 101120682 -SB - IM -MH - Cardiovascular Diseases/epidemiology/etiology/physiopathology -MH - *Cardiovascular Physiological Phenomena -MH - Humans -MH - Inflammation/complications/epidemiology -MH - Kidney Diseases/epidemiology/etiology/physiopathology -MH - Obesity/complications/epidemiology/metabolism/*physiopathology -MH - Oxidative Stress/physiology -MH - Risk Factors -MH - Sleep Apnea, Obstructive/epidemiology/etiology -EDAT- 2013/06/05 06:00 -MHDA- 2014/01/25 06:00 -CRDT- 2013/06/05 06:00 -PHST- 2013/06/05 06:00 [entrez] -PHST- 2013/06/05 06:00 [pubmed] -PHST- 2014/01/25 06:00 [medline] -AID - S1521-690X(13)00018-3 [pii] -AID - 10.1016/j.beem.2013.01.004 [doi] -PST - ppublish -SO - Best Pract Res Clin Endocrinol Metab. 2013 Apr;27(2):147-56. doi: - 10.1016/j.beem.2013.01.004. Epub 2013 Mar 1. - -PMID- 22713083 -OWN - NLM -STAT- MEDLINE -DCOM- 20120927 -LR - 20220311 -IS - 1751-2980 (Electronic) -IS - 1751-2972 (Linking) -VI - 13 -IP - 7 -DP - 2012 Jul -TI - Extragastrointestinal manifestations of Helicobacter pylori infection: facts or - myth? A critical review. -PG - 342-9 -LID - 10.1111/j.1751-2980.2012.00599.x [doi] -AB - Helicobacter pylori (H. pylori) infection is reported to be associated with many - extragastrointestinal manifestations, such as hematological diseases [idiopathic - thrombocytopenic purpura (ITP) and unexplained iron deficiency anemia (IDA)], - cardiovascular diseases (ischemic heart diseases), neurological disorders - (stroke, Parkinson's disease, Alzheimer's disease), obesity and skin disorders. - Among these, the best evidence so far is in ITP and unexplained IDA, with - high-quality studies showing the improvement of IDA and ITP after H. pylori - eradication. The evidence of its association with coronary artery disease is weak - and many of the results may be erroneous. The role of H. pylori infection in - affecting serum leptin and ghrelin levels has attracted a lot of attention - recently and available data to date have been conflicting. There have also been - many uncontrolled, small sample studies suggesting an association between H. - pylori infection and neurological disorders or chronic urticaria. However, more - studies are required to clarify such proposed causal links. -CI - © 2012 The Authors. Journal of Digestive Diseases © 2012 Chinese Medical - Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital - Affiliated to Shanghai Jiaotong University School of Medicine and Blackwell - Publishing Asia Pty Ltd. -FAU - Tan, Huck-Joo -AU - Tan HJ -AD - Department of Gastroenterology, Sunway Medical Centre, Selangor Department of - Gastroenterology, University of Malaya, Kuala Lumpur, Malaysia. - hucktan@hotmail.com -FAU - Goh, Khean-Lee -AU - Goh KL -LA - eng -PT - Journal Article -PT - Review -PL - Australia -TA - J Dig Dis -JT - Journal of digestive diseases -JID - 101302699 -RN - 0 (Ghrelin) -RN - 0 (Leptin) -SB - IM -MH - Anemia, Iron-Deficiency/microbiology -MH - Cardiovascular Diseases/microbiology -MH - Ghrelin/blood -MH - Helicobacter Infections/blood/*complications -MH - *Helicobacter pylori -MH - Humans -MH - Leptin/blood -MH - Nervous System Diseases/microbiology -MH - Obesity/microbiology -MH - Purpura, Thrombocytopenic, Idiopathic/microbiology -EDAT- 2012/06/21 06:00 -MHDA- 2012/09/28 06:00 -CRDT- 2012/06/21 06:00 -PHST- 2012/06/21 06:00 [entrez] -PHST- 2012/06/21 06:00 [pubmed] -PHST- 2012/09/28 06:00 [medline] -AID - 10.1111/j.1751-2980.2012.00599.x [doi] -PST - ppublish -SO - J Dig Dis. 2012 Jul;13(7):342-9. doi: 10.1111/j.1751-2980.2012.00599.x. - -PMID- 19952757 -OWN - NLM -STAT- MEDLINE -DCOM- 20100427 -LR - 20220411 -IS - 1741-8275 (Electronic) -IS - 1741-8267 (Linking) -VI - 17 -IP - 1 -DP - 2010 Feb -TI - Secondary prevention through cardiac rehabilitation: from knowledge to - implementation. A position paper from the Cardiac Rehabilitation Section of the - European Association of Cardiovascular Prevention and Rehabilitation. -PG - 1-17 -LID - 10.1097/HJR.0b013e3283313592 [doi] -AB - Increasing awareness of the importance of cardiovascular prevention is not yet - matched by the resources and actions within health care systems. Recent - publication of the European Commission's European Heart Health Charter in 2008 - prompts a review of the role of cardiac rehabilitation (CR) to cardiovascular - health outcomes. Secondary prevention through exercise-based CR is the - intervention with the best scientific evidence to contribute to decrease - morbidity and mortality in coronary artery disease, in particular after - myocardial infarction but also incorporating cardiac interventions and chronic - stable heart failure. The present position paper aims to provide the practical - recommendations on the core components and goals of CR intervention in different - cardiovascular conditions, to assist in the design and development of the - programmes, and to support healthcare providers, insurers, policy makers and - consumers in the recognition of the comprehensive nature of CR. Those charged - with responsibility for secondary prevention of cardiovascular disease, whether - at European, national or individual centre level, need to consider where and how - structured programmes of CR can be delivered to all patients eligible. Thus a - novel, disease-oriented document has been generated, where all components of CR - for cardiovascular conditions have been revised, presenting both well-established - and controversial aspects. A general table applicable to all cardiovascular - conditions and specific tables for each clinical disease have been created and - commented. -FAU - Piepoli, Massimo Francesco -AU - Piepoli MF -AD - Heart Failure Unit, Cardiac Department, Guglielmo da Saliceto Hospital, Piacenza, - Italy. m.piepoli@ausl.pc.it -FAU - Corrà, Ugo -AU - Corrà U -FAU - Benzer, Werner -AU - Benzer W -FAU - Bjarnason-Wehrens, Birna -AU - Bjarnason-Wehrens B -FAU - Dendale, Paul -AU - Dendale P -FAU - Gaita, Dan -AU - Gaita D -FAU - McGee, Hannah -AU - McGee H -FAU - Mendes, Miguel -AU - Mendes M -FAU - Niebauer, Josef -AU - Niebauer J -FAU - Zwisler, Ann-Dorthe Olsen -AU - Zwisler AD -FAU - Schmid, Jean-Paul -AU - Schmid JP -CN - Cardiac Rehabilitation Section of the European Association of Cardiovascular - Prevention and Rehabilitation -LA - eng -PT - Journal Article -PT - Practice Guideline -PT - Review -PL - England -TA - Eur J Cardiovasc Prev Rehabil -JT - European journal of cardiovascular prevention and rehabilitation : official - journal of the European Society of Cardiology, Working Groups on Epidemiology & - Prevention and Cardiac Rehabilitation and Exercise Physiology -JID - 101192000 -RN - 0 (Antihypertensive Agents) -RN - 0 (Hypolipidemic Agents) -SB - IM -MH - Antihypertensive Agents/therapeutic use -MH - Attitude of Health Personnel -MH - Awareness -MH - Counseling -MH - *Delivery of Health Care, Integrated -MH - Europe -MH - Evidence-Based Medicine -MH - Exercise Therapy -MH - Female -MH - *Health Knowledge, Attitudes, Practice -MH - Heart Diseases/etiology/*prevention & control/*rehabilitation -MH - Humans -MH - Hypolipidemic Agents/therapeutic use -MH - Male -MH - Nutrition Therapy -MH - Patient Education as Topic -MH - Risk Factors -MH - Risk Reduction Behavior -MH - *Secondary Prevention/methods -MH - Smoking Cessation -MH - Societies, Medical -MH - Treatment Outcome -MH - Weight Loss -RF - 54 -EDAT- 2009/12/03 06:00 -MHDA- 2010/04/28 06:00 -CRDT- 2009/12/03 06:00 -PHST- 2009/12/03 06:00 [entrez] -PHST- 2009/12/03 06:00 [pubmed] -PHST- 2010/04/28 06:00 [medline] -AID - 10.1097/HJR.0b013e3283313592 [doi] -PST - ppublish -SO - Eur J Cardiovasc Prev Rehabil. 2010 Feb;17(1):1-17. doi: - 10.1097/HJR.0b013e3283313592. - -PMID- 24113581 -OWN - NLM -STAT- MEDLINE -DCOM- 20140424 -LR - 20211021 -IS - 1422-0067 (Electronic) -IS - 1422-0067 (Linking) -VI - 14 -IP - 10 -DP - 2013 Oct 9 -TI - Non-coding RNAs: the "dark matter" of cardiovascular pathophysiology. -PG - 19987-20018 -LID - 10.3390/ijms141019987 [doi] -AB - Large-scale analyses of mammalian transcriptomes have identified a significant - number of different RNA molecules that are not translated into protein. In fact, - the use of new sequencing technologies has identified that most of the genome is - transcribed, producing a heterogeneous population of RNAs which do not encode for - proteins (ncRNAs). Emerging data suggest that these transcripts influence the - development of cardiovascular disease. The best characterized non-coding RNA - family is represented by short highly conserved RNA molecules, termed microRNAs - (miRNAs), which mediate a process of mRNA silencing through transcript - degradation or translational repression. These microRNAs (miRNAs) are expressed - in cardiovascular tissues and play key roles in many cardiovascular pathologies, - such as coronary artery disease (CAD) and heart failure (HF). Potential links - between other ncRNAs, like long non-coding RNA, and cardiovascular disease are - intriguing but the functions of these transcripts are largely unknown. Thus, the - functional characterization of ncRNAs is essential to improve the overall - understanding of cellular processes involved in cardiovascular diseases in order - to define new therapeutic strategies. This review outlines the current knowledge - of the different ncRNA classes and summarizes their role in cardiovascular - development and disease. -FAU - Iaconetti, Claudio -AU - Iaconetti C -AD - Division of Cardiology, Magna Graecia University, URT Consiglio Nazionale delle - Ricerche (CNR), Catanzaro 88100, Italy. indolfi@unicz.it. -FAU - Gareri, Clarice -AU - Gareri C -FAU - Polimeni, Alberto -AU - Polimeni A -FAU - Indolfi, Ciro -AU - Indolfi C -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131009 -PL - Switzerland -TA - Int J Mol Sci -JT - International journal of molecular sciences -JID - 101092791 -RN - 0 (RNA, Untranslated) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*genetics/*physiopathology -MH - Gene Expression Regulation/genetics -MH - Humans -MH - RNA, Untranslated/*genetics -PMC - PMC3821599 -EDAT- 2013/10/12 06:00 -MHDA- 2014/04/25 06:00 -PMCR- 2013/10/01 -CRDT- 2013/10/12 06:00 -PHST- 2013/07/04 00:00 [received] -PHST- 2013/09/12 00:00 [revised] -PHST- 2013/09/16 00:00 [accepted] -PHST- 2013/10/12 06:00 [entrez] -PHST- 2013/10/12 06:00 [pubmed] -PHST- 2014/04/25 06:00 [medline] -PHST- 2013/10/01 00:00 [pmc-release] -AID - ijms141019987 [pii] -AID - ijms-14-19987 [pii] -AID - 10.3390/ijms141019987 [doi] -PST - epublish -SO - Int J Mol Sci. 2013 Oct 9;14(10):19987-20018. doi: 10.3390/ijms141019987. - -PMID- 20548977 -OWN - NLM -STAT- MEDLINE -DCOM- 20100715 -LR - 20211020 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Print) -IS - 0828-282X (Linking) -VI - 26 -IP - 6 -DP - 2010 Jun-Jul -TI - The emerging clinical role of cardiovascular magnetic resonance imaging. -PG - 313-22 -AB - Starting as a research method little more than a decade ago, cardiovascular - magnetic resonance (CMR) imaging has rapidly evolved to become a powerful - diagnostic tool used in routine clinical cardiology. The contrast in CMR images - is generated from protons in different chemical environments and, therefore, - enables high-resolution imaging and specific tissue characterization in vivo, - without the use of potentially harmful ionizing radiation.CMR imaging is used for - the assessment of regional and global ventricular function, and to answer - questions regarding anatomy. State-of-the-art CMR sequences allow for a wide - range of tissue characterization approaches, including the identification and - quantification of nonviable, edematous, inflamed, infiltrated or hypoperfused - myocardium. These tissue changes are not only used to help identify the etiology - of cardiomyopathies, but also allow for a better understanding of tissue - pathology in vivo. CMR tissue characterization may also be used to stage a - disease process; for example, elevated T2 signal is consistent with edema and - helps differentiate acute from chronic myocardial injury, and the extent of - myocardial fibrosis as imaged by contrast-enhanced CMR correlates with adverse - patient outcome in ischemic and nonischemic cardiomyopathies.The current role of - CMR imaging in clinical cardiology is reviewed, including coronary artery - disease, congenital heart disease, nonischemic cardiomyopathies and valvular - disease. -FAU - Kumar, Andreas -AU - Kumar A -AD - Stephenson CMR Centre at the Libin Cardiovascular Institute of Alberta, - University of Calgary, Calgary, Alberta, Canada. -FAU - Patton, David J -AU - Patton DJ -FAU - Friedrich, Matthias G -AU - Friedrich MG -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Cardiovascular Diseases/*diagnosis -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Reproducibility of Results -PMC - PMC2903987 -EDAT- 2010/06/16 06:00 -MHDA- 2010/07/16 06:00 -PMCR- 2011/06/01 -CRDT- 2010/06/16 06:00 -PHST- 2010/06/16 06:00 [entrez] -PHST- 2010/06/16 06:00 [pubmed] -PHST- 2010/07/16 06:00 [medline] -PHST- 2011/06/01 00:00 [pmc-release] -AID - S0828-282X(10)70396-2 [pii] -AID - cjc26313 [pii] -AID - 10.1016/s0828-282x(10)70396-2 [doi] -PST - ppublish -SO - Can J Cardiol. 2010 Jun-Jul;26(6):313-22. doi: 10.1016/s0828-282x(10)70396-2. - -PMID- 20188845 -OWN - NLM -STAT- MEDLINE -DCOM- 20100617 -LR - 20151119 -IS - 1873-488X (Electronic) -IS - 1056-8719 (Linking) -VI - 61 -IP - 2 -DP - 2010 Mar-Apr -TI - Measurement of myocardial infarct size in preclinical studies. -PG - 163-70 -LID - 10.1016/j.vascn.2010.02.014 [doi] -AB - Ischemic heart disease is a major cause of morbidity and mortality worldwide. - Myocardial ischemia followed by reperfusion results in tissue injury termed - ischemia/reperfusion injury which is characterized by decreased myocardial - contractile function, occurrence of arrhythmias, and development of tissue - necrosis (infarction). These pathologies are all relevant as clinical - consequences of myocardial ischemia/reperfusion injury and they are also - important as experimental correlates and endpoints. The most critical determinant - of acute and long-term mortality after myocardial infarction is the volume of the - infarcted tissue. Therefore, development of cardioprotective therapies aims at - reducing the size of the infarct developing due to myocardial - ischemia/reperfusion injury. Different techniques are available to measure - myocardial infarct size in humans and in experimental settings, however, accurate - determination of the extent of infarction is necessary to evaluate interventions - that may delay the onset of necrosis and/or limit the total extent of infarct - size during ischemia/reperfusion. This paper highlights recent advances of the - different techniques to measure infarct size. -CI - Copyright 2010 Elsevier Inc. All rights reserved. -FAU - Csonka, Csaba -AU - Csonka C -AD - Cardiovascular Research Group, Department of Biochemistry, University of Szeged, - Szeged, Hungary. csaba.csonka@pharmahungary.com -FAU - Kupai, Krisztina -AU - Kupai K -FAU - Kocsis, Gabriella F -AU - Kocsis GF -FAU - Novák, Gábor -AU - Novák G -FAU - Fekete, Veronika -AU - Fekete V -FAU - Bencsik, Péter -AU - Bencsik P -FAU - Csont, Tamás -AU - Csont T -FAU - Ferdinandy, Péter -AU - Ferdinandy P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100225 -PL - United States -TA - J Pharmacol Toxicol Methods -JT - Journal of pharmacological and toxicological methods -JID - 9206091 -RN - 0 (Biomarkers) -RN - 0 (Cardiotonic Agents) -RN - 0 (Coloring Agents) -RN - 0 (Tetrazolium Salts) -RN - 7OL20RET2I (triphenyltetrazolium) -SB - IM -MH - Animals -MH - Biomarkers -MH - Cardiotonic Agents/*pharmacology -MH - Coloring Agents -MH - Coronary Vessels/pathology -MH - Drug Evaluation, Preclinical -MH - Electrocardiography -MH - Magnetic Resonance Imaging -MH - Myocardial Infarction/mortality/*pathology -MH - Myocardial Reperfusion Injury/pathology -MH - Myocardium/*pathology -MH - Positron-Emission Tomography -MH - Tetrazolium Salts -MH - Tomography, Emission-Computed, Single-Photon -MH - Tomography, X-Ray Computed -RF - 57 -EDAT- 2010/03/02 06:00 -MHDA- 2010/06/18 06:00 -CRDT- 2010/03/02 06:00 -PHST- 2010/01/11 00:00 [received] -PHST- 2010/02/19 00:00 [revised] -PHST- 2010/02/20 00:00 [accepted] -PHST- 2010/03/02 06:00 [entrez] -PHST- 2010/03/02 06:00 [pubmed] -PHST- 2010/06/18 06:00 [medline] -AID - S1056-8719(10)00030-4 [pii] -AID - 10.1016/j.vascn.2010.02.014 [doi] -PST - ppublish -SO - J Pharmacol Toxicol Methods. 2010 Mar-Apr;61(2):163-70. doi: - 10.1016/j.vascn.2010.02.014. Epub 2010 Feb 25. - -PMID- 19845526 -OWN - NLM -STAT- MEDLINE -DCOM- 20100126 -LR - 20181201 -IS - 0022-9040 (Print) -IS - 0022-9040 (Linking) -VI - 49 -IP - 10 -DP - 2009 -TI - [Thienopyridines in the treatment and prevention of cardiovascular diseases. Part - II. Clinical pharmacology of clopidogrel]. -PG - 88-96 -AB - In a series of articles the authors consider clinical pharmacology and experience - of clinical application of blockers of platelet P2Y12 receptors, most well known - representatives of which ticlopidine and clopidogrel according to chemical - structure belong to thienopyridine derivatives. In the second communication we - describe in detail clinical pharmacokinetics and pharmacodynamics of the most - often used thienopyridine derivative - clopidogrel. We discuss results of - randomized studies and clinical observations which have shown that - pharmacokinetics of clopidogrel might vary substantially in dependence of - polymorphisms of genes responsible for synthesis of P2Y12 receptors of platelets - or cytochromic isoenzymes P-450 CYP of liver with participation of which - formation of active metabolite of clopidogrel occurs. Contrary to practically - healthy people in patients with various forms of ischemic heart disease (IHD) - concomitant therapy, for instance some statins and calcium antagonists, can - affect clopidogrel pharmacokinetics. Pharmacodynamics of clopidogrel in patients - with IHD with acute coronary syndrome or diabetes mellitus or before percutaneous - coronary interventions (PCI) also differs from that in healthy people, because in - these patients hyperaggregation of platelets takes place initially and - antiaggregatory action of clopidogrel is less expressed. In 10-30% of patients - with IHD partial or complete resistance to antiaggregation action of clopidogrel - is detected, which according to some observations is combined with elevated risk - of thrombotic cardiac complications after PCI. Possible causes of resistance to - clopidogrel and ways of its overcoming are discussed. -FAU - Preobrazhenskiĭ, D V -AU - Preobrazhenskiĭ DV -FAU - Sidorenko, B A -AU - Sidorenko BA -FAU - Batyraliev, T A -AU - Batyraliev TA -FAU - Vural, A -AU - Vural A -FAU - Islek, M -AU - Islek M -FAU - Avsar, O -AU - Avsar O -LA - rus -PT - Journal Article -PT - Review -PL - Russia (Federation) -TA - Kardiologiia -JT - Kardiologiia -JID - 0376351 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Pyridines) -RN - 0 (thienopyridine) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - *Cardiovascular Diseases/drug therapy/metabolism/prevention & control -MH - Clopidogrel -MH - Humans -MH - Platelet Aggregation Inhibitors/pharmacokinetics/*therapeutic use -MH - Pyridines/pharmacokinetics/*therapeutic use -MH - Ticlopidine/*analogs & derivatives/pharmacokinetics/therapeutic use -MH - Treatment Outcome -RF - 63 -EDAT- 2009/10/23 06:00 -MHDA- 2010/01/27 06:00 -CRDT- 2009/10/23 06:00 -PHST- 2009/10/23 06:00 [entrez] -PHST- 2009/10/23 06:00 [pubmed] -PHST- 2010/01/27 06:00 [medline] -PST - ppublish -SO - Kardiologiia. 2009;49(10):88-96. - -PMID- 17106175 -OWN - NLM -STAT- MEDLINE -DCOM- 20070209 -LR - 20191026 -IS - 1345-4676 (Print) -IS - 1345-4676 (Linking) -VI - 73 -IP - 5 -DP - 2006 Oct -TI - Clinical applications of ECG-gated myocardial perfusion SPECT. -PG - 248-57 -AB - Erectrocardiogram (ECG)-gated myocardial perfusion single photon emission - computed tomography (SPECT) can be used to assess myocardial perfusion and left - ventricular function simultaneously. Various clinical applications of gated SPECT - and their usefulness have been reported. The functional variables that can be - determined with gated SPECT have been limited to systolic indices. Therefore, we - evaluated left ventricular diastolic function with gated SPECT using data - obtained from various frames per cardiac cycle and found that date generated from - 32-frames are suitable for clinical use. Serial assessment of left ventricular - function was also performed during bicycle exercise and dobutamine stress by - means of gated SPECT using short-time data collection. These techniques, - therefore, have the potential to provide useful information for evaluating - myocardial conditions, such as hibernation and residual ischemia in infarct - areas. Recently, we have developed a new technique for three-dimensional - registration of CT coronary angiography (CTCA) and ECG-gated myocardial perfusion - SPECT. This technique of registration may assist the integration of information - from gated SPECT and CTCA and may have clinical application for the diagnosis of - ischemic heart disease. These various applications would contribute to the - development of nuclear cardiology. -FAU - Kumita, Shin-ichiro -AU - Kumita S -AD - Department of Clinical Radiology, Nippon Medical School Graduate School of - Medicine, Tokyo, Japan. s-kumita@nms.ac.jp -FAU - Cho, Keiichi -AU - Cho K -FAU - Nakajo, Hidenobu -AU - Nakajo H -FAU - Toba, Masahiro -AU - Toba M -FAU - Fukushima, Yoshimitsu -AU - Fukushima Y -FAU - Mizumura, Sunao -AU - Mizumura S -FAU - Kumazaki, Tatsuo -AU - Kumazaki T -LA - eng -PT - Journal Article -PT - Review -PL - Japan -TA - J Nippon Med Sch -JT - Journal of Nippon Medical School = Nippon Ika Daigaku zasshi -JID - 100935589 -RN - 0 (Fatty Acids) -RN - 3S12J47372 (Dobutamine) -SB - IM -MH - Coronary Angiography -MH - Dobutamine -MH - Electrocardiography -MH - Exercise Test -MH - Fatty Acids/metabolism -MH - Humans -MH - Myocardial Ischemia/diagnosis -MH - Tomography, Emission-Computed, Single-Photon/*methods -MH - Tomography, X-Ray Computed -MH - Ventricular Function, Left/*physiology -RF - 25 -EDAT- 2006/11/16 09:00 -MHDA- 2007/02/10 09:00 -CRDT- 2006/11/16 09:00 -PHST- 2006/11/16 09:00 [pubmed] -PHST- 2007/02/10 09:00 [medline] -PHST- 2006/11/16 09:00 [entrez] -AID - JST.JSTAGE/jnms/73.248 [pii] -AID - 10.1272/jnms.73.248 [doi] -PST - ppublish -SO - J Nippon Med Sch. 2006 Oct;73(5):248-57. doi: 10.1272/jnms.73.248. - -PMID- 17166606 -OWN - NLM -STAT- MEDLINE -DCOM- 20070731 -LR - 20070625 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 119 -IP - 3 -DP - 2007 Jul 31 -TI - Myocardial ischemia and ventricular fibrillation: pathophysiology and clinical - implications. -PG - 283-90 -AB - Ventricular fibrillation (VF) and myocardial ischemia are inseparable. The first - clinical manifestation of myocardial ischemia or infarction may be sudden cardiac - death in 20-25% of patients. The occurrence of potentially lethal arrhythmia is - the end result of a cascade of pathophysiological abnormalities that result from - complex interactions between coronary vascular events, myocardial injury, and - changes in autonomic tone, metabolic conditions and ionic state of the - myocardium. It is also related to the time from the onset of ischemia. Within the - first few minutes there is abundant ventricular arrhythmogenesis usually lasting - for 30 min. Triggers for ischemic VF occur at the border zone or regionally - ischemic heart. The border zone of ischemia is the predominant site of - fragmentation. Acute ischemia opens K(ATP) channels and causes acidosis and - hypoxia of myocardial cells leading to a large dispersion in repolarization - across the border zone. Abnormalities of intracellular Ca2+ handling also occur - in the first few minutes of acute myocardial ischemia and may be an important - cause of arrhythmias in human coronary artery disease. Substrate on the other - hand transforms triggers into VF and serves to maintain it through fragmentation - of waves in the ischemic zone. Thrombin levels, stretch, catecholamine, genetic - predisposition, etc. are some of these factors. Reentry models described are - spiral wave reentry, 3 dimensional rotors, reentry around 'M' cells and - figure-of-eight reentry. Continuing efforts to better understand these - arrhythmias will help identify patients of myocardial ischemia prone to - arrhythmias. -FAU - Luqman, Nazar -AU - Luqman N -AD - The Department of Cardiology, RIPAS Hospital, Brunei Darussalam. -FAU - Sung, Ruey J -AU - Sung RJ -FAU - Wang, Chun-Li -AU - Wang CL -FAU - Kuo, Chi-Tai -AU - Kuo CT -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20061212 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Calcium Channels) -RN - 0 (Potassium Channels) -SB - IM -MH - Calcium Channels/physiology -MH - Humans -MH - Myocardial Ischemia/*complications/*physiopathology -MH - Potassium Channels/physiology -MH - Risk Factors -MH - Ventricular Fibrillation/*etiology/*physiopathology -RF - 64 -EDAT- 2006/12/15 09:00 -MHDA- 2007/08/01 09:00 -CRDT- 2006/12/15 09:00 -PHST- 2006/02/20 00:00 [received] -PHST- 2006/07/31 00:00 [revised] -PHST- 2006/09/24 00:00 [accepted] -PHST- 2006/12/15 09:00 [pubmed] -PHST- 2007/08/01 09:00 [medline] -PHST- 2006/12/15 09:00 [entrez] -AID - S0167-5273(06)01326-X [pii] -AID - 10.1016/j.ijcard.2006.09.016 [doi] -PST - ppublish -SO - Int J Cardiol. 2007 Jul 31;119(3):283-90. doi: 10.1016/j.ijcard.2006.09.016. Epub - 2006 Dec 12. - -PMID- 19006047 -OWN - NLM -STAT- MEDLINE -DCOM- 20081125 -LR - 20131121 -IS - 1439-4413 (Electronic) -IS - 0012-0472 (Linking) -VI - 133 -IP - 47 -DP - 2008 Nov -TI - [Endothelial dysfunction: pathophysiology, diagnosis and prognosis]. -PG - 2465-70 -LID - 10.1055/s-0028-1100941 [doi] -AB - The endothelium plays a crucial role in the regulation of vascular tone. Recent - studies have indicated that endothelial dysfunction develops in the presence of - cardiovascular risk factors such as hypertension, diabetes mellitus, - hypercholesterolemia and in chronic smokers, as well as in patients with a family - history of cardiovascular disease. It has now been established that endothelial - dysfunction represents the first indicator of vascular damage. Endothelial - function can be assessed in coronary and peripheral conductance and resistance - vessels by means of invasive and noninvasive (ultrasound-guided) methods such as - intracoronary infusion of acetylcholine, the endothelium-dependent vasodilator. - It is interesting that endothelial dysfunction in the presence of cardiovascular - risk factors can be almost completely corrected by the acute administration of - antioxidants such as vitamin C, pointing to a crucial role of reactive oxygen - species in mediating this phenomenon. Superoxide producing enzymes involved in - the increased production of reactive oxygen species include NADPH oxidase, nitric - oxide synthase in the uncoupled state, mitochondrial superoxide sources, - cyclooxygenase and xanthine oxidase. Recent studies indicate that the endothelial - dysfunction found in coronary and peripheral conductance and resistance vessels - provide prognostic information about future cardiovascular events. The role of - endothelial dysfunction in the setting of primary prevention is not yet clear, - but is being investigated in the current Gutenberg Heart Study. -FAU - Münzel, T -AU - Münzel T -AD - II. Medizinische Klinik, Johannes Gutenberg Universität Mainz, Mainz. - tmuenzel@uni-mainz.de -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Endotheliale Dysfunktion: Pathophysiologie, Diagnostik und prognostische - Bedeutung. -DEP - 20081112 -PL - Germany -TA - Dtsch Med Wochenschr -JT - Deutsche medizinische Wochenschrift (1946) -JID - 0006723 -RN - 31C4KY9ESH (Nitric Oxide) -SB - IM -MH - Cardiovascular Diseases/diagnosis/genetics/*physiopathology -MH - Diabetes Mellitus/diagnosis/physiopathology -MH - Endothelium, Vascular/*physiopathology -MH - Humans -MH - Hypercholesterolemia/diagnosis/physiopathology -MH - Hypertension/diagnosis/physiopathology -MH - Nitric Oxide/physiology -MH - Prognosis -MH - Risk Factors -MH - Smoking/physiopathology -RF - 32 -EDAT- 2008/11/14 09:00 -MHDA- 2008/12/17 09:00 -CRDT- 2008/11/14 09:00 -PHST- 2008/11/14 09:00 [pubmed] -PHST- 2008/12/17 09:00 [medline] -PHST- 2008/11/14 09:00 [entrez] -AID - 10.1055/s-0028-1100941 [doi] -PST - ppublish -SO - Dtsch Med Wochenschr. 2008 Nov;133(47):2465-70. doi: 10.1055/s-0028-1100941. Epub - 2008 Nov 12. - -PMID- 18474176 -OWN - NLM -STAT- MEDLINE -DCOM- 20080922 -LR - 20220330 -IS - 1534-3111 (Electronic) -IS - 1522-6417 (Linking) -VI - 10 -IP - 2 -DP - 2008 Apr -TI - Arterial structure and function in end-stage renal disease. -PG - 107-11 -AB - Cardiovascular disease is a major cause of morbidity and mortality in patients - with end-stage renal disease (ESRD). Macrovascular disease develops rapidly in - ESRD patients and is responsible for the high incidence of left ventricular - hypertrophy, ischemic heart disease, cerebrovascular accidents, and peripheral - artery diseases. Occlusive lesions due to atheromatous plaques frequently cause - these complications; however, atherosclerosis represents only one form of - structural response to metabolic and hemodynamic alterations interfering with the - "natural" process of aging. The spectrum of arterial alterations in ESRD is - broader, including large artery remodeling, changes in viscoelastic properties, - and stiffening of arterial walls. Nonatheromatous remodeling principally changes - the dampening function of arteries, characterized by stiffening of arterial walls - and with deleterious effects on the left ventricle and coronary perfusion. The - origin of arterial stiffening in ESRD patients is multifactorial, with extensive - arterial calcifications as an important covariate. -FAU - Guérin, Alain P -AU - Guérin AP -AD - Hôpital Manhès, 8 rue Roger Clavier, Fleury-Mérogis, 91712, France. -FAU - Pannier, Bruno -AU - Pannier B -FAU - Marchais, Sylvain J -AU - Marchais SJ -FAU - London, Gérard M -AU - London GM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Hypertens Rep -JT - Current hypertension reports -JID - 100888982 -SB - IM -MH - Arteries/*pathology/*physiopathology -MH - Arteriosclerosis/pathology/physiopathology -MH - Atherosclerosis/pathology/physiopathology -MH - Cardiovascular Diseases/etiology/*pathology/*physiopathology -MH - Disease Progression -MH - Endothelium, Vascular/pathology/physiopathology -MH - Humans -MH - Kidney Failure, Chronic/*complications/pathology/physiopathology -RF - 47 -EDAT- 2008/05/14 09:00 -MHDA- 2008/09/23 09:00 -CRDT- 2008/05/14 09:00 -PHST- 2008/05/14 09:00 [pubmed] -PHST- 2008/09/23 09:00 [medline] -PHST- 2008/05/14 09:00 [entrez] -AID - 10.1007/s11906-008-0021-2 [doi] -PST - ppublish -SO - Curr Hypertens Rep. 2008 Apr;10(2):107-11. doi: 10.1007/s11906-008-0021-2. - -PMID- 21130968 -OWN - NLM -STAT- MEDLINE -DCOM- 20110321 -LR - 20110425 -IS - 1875-2128 (Electronic) -IS - 1875-2128 (Linking) -VI - 103 -IP - 10 -DP - 2010 Oct -TI - Paediatric cardiac intensive care unit: current setting and organization in 2010. -PG - 546-51 -LID - 10.1016/j.acvd.2010.05.004 [doi] -AB - Over recent decades, specialized paediatric cardiac intensive care has emerged as - a central component in the management of critically ill, neonatal, paediatric and - adult patients with congenital and acquired heart disease. The majority of - high-volume centres (dealing with over 300 surgical cases per year) have - dedicated paediatric cardiac intensive care units, with the smallest programmes - more likely to care for paediatric cardiac patients in mixed paediatric or adult - intensive care units. Specialized nursing staff are also a crucial presence at - the patient's bedside for quality of care. A paediatric cardiac intensive care - programme should have patients (preoperative and postoperative) grouped together - geographically, and should provide proximity to the operating theatre, - catheterization laboratory and radiology department, as well as to the regular - ward. Age-appropriate medical equipment must be provided. An optimal strategy for - running a paediatric cardiac intensive care programme should include: - multidisciplinary collaboration and involvement with paediatric cardiology, - anaesthesia, cardiac surgery and many other subspecialties; a risk-stratification - strategy for quantifying perioperative risk; a personalized patient approach; and - anticipatory care. Finally, progressive withdrawal from heavy paediatric cardiac - intensive care management should be institutionalized. Although the countries of - the European Union do not share any common legislation on the structure and - organization of paediatric intensive care or paediatric cardiac intensive care, - any paediatric cardiac surgery programme in France that is agreed by the French - Health Ministry must perform at least '150 major procedures per year in children' - and must provide a 'specialized paediatric intensive care unit'. -CI - Copyright © 2010 Elsevier Masson SAS. All rights reserved. -FAU - Fraisse, Alain -AU - Fraisse A -AD - Cardiologie pédiatrique, hôpital d'enfants de la Timone, 264 rue Saint-Pierre, - Marseille cedex 5, France. alain.fraisse@ap-hm.fr -FAU - Le Bel, Stéphane -AU - Le Bel S -FAU - Mas, Bertrand -AU - Mas B -FAU - Macrae, Duncan -AU - Macrae D -LA - eng -PT - Journal Article -PT - Review -DEP - 20100826 -PL - Netherlands -TA - Arch Cardiovasc Dis -JT - Archives of cardiovascular diseases -JID - 101465655 -SB - IM -MH - Cardiology Service, Hospital/*organization & administration -MH - Continuity of Patient Care -MH - Cooperative Behavior -MH - Coronary Care Units/*organization & administration -MH - Delivery of Health Care, Integrated -MH - Equipment Design -MH - Heart Defects, Congenital/nursing/*therapy -MH - Heart Diseases/nursing/*therapy -MH - Hospital Design and Construction -MH - Humans -MH - Intensive Care Units, Pediatric/*organization & administration -MH - Nursing Staff, Hospital/organization & administration -MH - Organizational Objectives -MH - Patient Care Team/organization & administration -MH - Quality of Health Care -MH - Risk Assessment -EDAT- 2010/12/07 06:00 -MHDA- 2011/03/22 06:00 -CRDT- 2010/12/07 06:00 -PHST- 2010/03/05 00:00 [received] -PHST- 2010/05/17 00:00 [revised] -PHST- 2010/05/18 00:00 [accepted] -PHST- 2010/12/07 06:00 [entrez] -PHST- 2010/12/07 06:00 [pubmed] -PHST- 2011/03/22 06:00 [medline] -AID - S1875-2136(10)00136-1 [pii] -AID - 10.1016/j.acvd.2010.05.004 [doi] -PST - ppublish -SO - Arch Cardiovasc Dis. 2010 Oct;103(10):546-51. doi: 10.1016/j.acvd.2010.05.004. - Epub 2010 Aug 26. - -PMID- 16572983 -OWN - NLM -STAT- MEDLINE -DCOM- 20060414 -LR - 20181201 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 7 -IP - 3 -DP - 2006 Mar -TI - [Secondary prevention of acute coronary syndromes: are we following correctly the - guidelines?]. -PG - 176-85 -AB - Heart diseases are the leading cause of death and morbidity in western countries - and among them acute coronary artery diseases result to be the major contributor. - During the last few decades a lot of energy has been mostly applied to the acute - phase of non-ST-elevation acute coronary syndromes (ACS), where cardiac events - concentrate. In fact a timely risk stratification along with an early aggressive - invasive strategy and very powerful antithrombotic treatment have profoundly - improved the in-hospital prognosis of such patients. Such a strong emphasis on - the acute phase of ACS could have limited the interest in the equally important - post-discharge therapies. However, several studies have demonstrated that - different preventive treatments (aspirin, beta-blockers, angiotensin-converting - enzyme inhibitors, statins and clopidogrel) could substantially reduce the - long-term mortality and morbidity of such patients. Therefore, current guidelines - emphasize the role of aggressive secondary preventive treatments after ACS. - However, a strong discrepancy between the indications of the guidelines and their - application in the real world arises day by day. Such a discrepancy could be due - to errors of omission or therapeutic paradoxes. Since patients with ACS are a - subgroup of subjects where secondary preventive measures could be useful and - cost-effective, cardiologists should not limit their attention to the acute phase - of the disease but should eagerly concentrate their efforts on an aggressive - secondary preventive treatment as well. Pursuing such a task could extend and - magnify the benefits obtained with acute treatment of ACS and significantly - improve the outcomes of such patients. Therefore, the role of the Scientific - Societies is to improve the application of guidelines and the utilization of all - evidence-based treatments even in such post-discharge phase. -FAU - Casella, Gianni -AU - Casella G -AD - U.O. di Cardiologia, Ospedale Maggiore, Bologna. gcas@fastmail.it -FAU - Greco, Cesare -AU - Greco C -FAU - Maggioni, Aldo P -AU - Maggioni AP -FAU - Di Pasquale, Giuseppe -AU - Di Pasquale G -LA - ita -PT - Comparative Study -PT - Journal Article -PT - Review -TT - La prevenzione secondaria delle sindromi coronariche acute: stiamo disattendendo - le linee guida? -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Hypolipidemic Agents) -RN - 0 (Platelet Aggregation Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Acute Disease -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Algorithms -MH - Angina, Unstable/diagnosis/drug therapy/mortality/*prevention & control -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Aspirin/therapeutic use -MH - Chest Pain/diagnosis/therapy -MH - Clinical Trials as Topic -MH - Clopidogrel -MH - Cost-Benefit Analysis -MH - Diagnosis, Differential -MH - Electrocardiography -MH - *Evidence-Based Medicine -MH - Fibrinolytic Agents/therapeutic use -MH - Forecasting -MH - *Guideline Adherence -MH - Humans -MH - Hypolipidemic Agents/therapeutic use -MH - Myocardial Infarction/diagnosis/drug therapy/mortality/*prevention & control -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Practice Guidelines as Topic -MH - Prognosis -MH - Risk Assessment -MH - Syndrome -MH - Ticlopidine/analogs & derivatives/therapeutic use -RF - 56 -EDAT- 2006/04/01 09:00 -MHDA- 2006/04/15 09:00 -CRDT- 2006/04/01 09:00 -PHST- 2006/04/01 09:00 [pubmed] -PHST- 2006/04/15 09:00 [medline] -PHST- 2006/04/01 09:00 [entrez] -PST - ppublish -SO - G Ital Cardiol (Rome). 2006 Mar;7(3):176-85. - -PMID- 17063167 -OWN - NLM -STAT- MEDLINE -DCOM- 20061124 -LR - 20220330 -IS - 1743-4300 (Electronic) -IS - 1743-4297 (Linking) -VI - 3 -IP - 11 -DP - 2006 Nov -TI - Primer: practical approach to the selection of patients for and application of - EECP. -PG - 623-32 -AB - Over the past decade, the frequency of use of enhanced external counterpulsation - (EECP) has increased in patients with angina, irrespective of medical therapy and - coronary revascularization status. Many patients referred for EECP have one or - more comorbidities that could affect this treatment's efficacy, safety, or both. - By use of data from more than 8,000 patients enrolled in the International EECP - Patient Registry, we provide practical guidelines for the selection and treatment - of patients. We have focused on considerations for patients who have one or more - of the following characteristics: age older than 75 years, diabetes, obesity, - heart failure, and peripheral vascular disease. We have also reviewed outcomes - and treatment recommendations for individuals with poor diastolic augmentation - during treatment, for those with atrial fibrillation or pacemakers, and for those - receiving anticoagulation therapy. Lastly, we examined relevant data regarding - extended courses of EECP, repeat therapy, or both. While clinical studies have - demonstrated the usefulness of EECP in selected patients, these guidelines permit - recommendations for the extended application of this important treatment to - subsets of patients excluded from clinical trials. -FAU - Michaels, Andrew D -AU - Michaels AD -AD - Division of Cardiology, University of Utah, Room 4A100, 30 North 1900 East, Salt - Lake City, UT 84132-2401, USA. andrew.michaels@hsc.utah.edu -FAU - McCullough, Peter A -AU - McCullough PA -FAU - Soran, Ozlem Z -AU - Soran OZ -FAU - Lawson, William E -AU - Lawson WE -FAU - Barsness, Gregory W -AU - Barsness GW -FAU - Henry, Timothy D -AU - Henry TD -FAU - Linnemeier, Georgiann -AU - Linnemeier G -FAU - Ochoa, Anthony -AU - Ochoa A -FAU - Kelsey, Sheryl F -AU - Kelsey SF -FAU - Kennard, Elizabeth D -AU - Kennard ED -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Nat Clin Pract Cardiovasc Med -JT - Nature clinical practice. Cardiovascular medicine -JID - 101226507 -SB - IM -MH - Aged -MH - Angina Pectoris/complications/physiopathology/*therapy -MH - Atrial Fibrillation/complications/physiopathology/therapy -MH - Coronary Circulation -MH - *Counterpulsation -MH - Defibrillators -MH - Female -MH - Humans -MH - Male -MH - Pacemaker, Artificial -MH - *Patient Selection -MH - Practice Guidelines as Topic -MH - Randomized Controlled Trials as Topic -MH - Recurrence -MH - Registries -MH - Time Factors -RF - 25 -EDAT- 2006/10/26 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/10/26 09:00 -PHST- 2006/04/18 00:00 [received] -PHST- 2006/07/26 00:00 [accepted] -PHST- 2006/10/26 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/10/26 09:00 [entrez] -AID - ncpcardio0691 [pii] -AID - 10.1038/ncpcardio0691 [doi] -PST - ppublish -SO - Nat Clin Pract Cardiovasc Med. 2006 Nov;3(11):623-32. doi: 10.1038/ncpcardio0691. - -PMID- 21518037 -OWN - NLM -STAT- MEDLINE -DCOM- 20110920 -LR - 20250529 -IS - 1365-2796 (Electronic) -IS - 0954-6820 (Linking) -VI - 270 -IP - 2 -DP - 2011 Aug -TI - Vascular imaging with positron emission tomography. -PG - 99-109 -LID - 10.1111/j.1365-2796.2011.02392.x [doi] -AB - Atherosclerosis is an inflammatory disease that causes most myocardial - infarctions, strokes and acute coronary syndromes. Despite the identification of - multiple risk factors and widespread use of drug therapies, it still remains a - global health concern with associated costs. Although angiography is established - as the gold standard means of detecting coronary artery stenosis, it does not - image the vessel wall itself, reporting only on its consequences such as luminal - narrowing and obstruction. MRI and computed tomography provide more information - about the plaque structure, but recently positron emission tomography (PET) - imaging using [(18) F]-fluorodeoxyglucose (FDG) has been advocated as a means of - measuring arterial inflammation. This results from the ability of FDG-PET to - highlight areas of high glucose metabolism, a feature of macrophages within - atherosclerosis, particularly in high-risk plaques. It is suggested that the - degree of FDG accumulation in the vessel wall reflects underlying inflammation - levels and that tracking any changes in FDG uptake over time or with drug therapy - might be a way of getting an early efficacy readout for novel - anti-atherosclerotic drugs. Early reports also demonstrate that FDG uptake is - correlated with the number of cardiovascular risk factors and possibly even the - risk of future cardiovascular events. This review will outline the evidence base, - shortcomings and emerging applications for FDG-PET in vascular imaging. - Alternative PET tracers and other candidate imaging modalities for measuring - vascular inflammation will also be discussed. -CI - © 2011 The Association for the Publication of the Journal of Internal Medicine. -FAU - Joshi, F -AU - Joshi F -AD - Division of Cardiovascular Medicine, University of Cambridge, Cambridge, UK. -FAU - Rosenbaum, D -AU - Rosenbaum D -FAU - Bordes, S -AU - Bordes S -FAU - Rudd, J H F -AU - Rudd JH -LA - eng -GR - FS/12/29/29463/BHF_/British Heart Foundation/United Kingdom -GR - PG/09/083/27667/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110518 -PL - England -TA - J Intern Med -JT - Journal of internal medicine -JID - 8904841 -RN - 0 (Radiopharmaceuticals) -RN - 0Z5B2CJX4D (Fluorodeoxyglucose F18) -RN - IY9XDZ35W2 (Glucose) -SB - IM -MH - Atherosclerosis/*diagnostic imaging/metabolism -MH - *Fluorodeoxyglucose F18/pharmacokinetics -MH - Glucose/metabolism -MH - Humans -MH - Inflammation/diagnostic imaging -MH - Macrophages/metabolism -MH - Positron-Emission Tomography/*methods -MH - *Radiopharmaceuticals/pharmacokinetics -EDAT- 2011/04/27 06:00 -MHDA- 2011/09/21 06:00 -CRDT- 2011/04/27 06:00 -PHST- 2011/04/27 06:00 [entrez] -PHST- 2011/04/27 06:00 [pubmed] -PHST- 2011/09/21 06:00 [medline] -AID - 10.1111/j.1365-2796.2011.02392.x [doi] -PST - ppublish -SO - J Intern Med. 2011 Aug;270(2):99-109. doi: 10.1111/j.1365-2796.2011.02392.x. Epub - 2011 May 18. - -PMID- 19440413 -OWN - NLM -STAT- MEDLINE -DCOM- 20090805 -LR - 20241127 -IS - 1660-4601 (Electronic) -IS - 1661-7827 (Print) -IS - 1660-4601 (Linking) -VI - 6 -IP - 2 -DP - 2009 Feb -TI - The control of environmental tobacco smoke: a policy review. -PG - 741-58 -LID - 10.3390/ijerph6020741 [doi] -AB - According to World Health Organisation figures, 30% of all cancer deaths, 20% of - all coronary heart diseases and strokes and 80% of all chronic obstructive - pulmonary disease are caused by cigarette smoking. Environmental Tobacco Smoke - (ETS) exposure has also been shown to be associated with disease and premature - death in non-smokers. In response to this environmental health issue, several - countries have brought about a smoking ban policy in public places and in the - workplace. Countries such as the U.S., France, Italy, Ireland, Malta, the - Netherlands, Sweden, Scotland, Spain, and England have all introduced policies - aimed at reducing the population exposure to ETS. Several investigations have - monitored the effectiveness of these smoking ban policies in terms of ETS - concentrations, human health and smoking prevalence, while others have also - investigated a number of alternatives to smoking ban policy measures. This paper - reviews the state of the art in research, carried out in the field of ETS, - smoking bans and Tobacco Control to date and highlights the need for future - research in the area. -FAU - McNabola, Aonghus -AU - McNabola A -AD - Department of Civil, Structural and Environmental Engineering, University of - Dublin, Trinity College, Ireland. amcnabol@tcd.ie -FAU - Gill, Laurence William -AU - Gill LW -LA - eng -PT - Journal Article -PT - Review -DEP - 20090220 -PL - Switzerland -TA - Int J Environ Res Public Health -JT - International journal of environmental research and public health -JID - 101238455 -RN - 0 (Air Pollutants) -SB - IM -MH - *Air Pollutants -MH - Environmental Exposure -MH - *Health Policy -MH - Prevalence -MH - Smoking/epidemiology/*legislation & jurisprudence -MH - World Health Organization -MH - Tobacco Products -PMC - PMC2672352 -OTO - NOTNLM -OT - ETS -OT - Smoking Areas -OT - Smoking Ban -OT - Tobacco Control -EDAT- 2009/05/15 09:00 -MHDA- 2009/08/06 09:00 -PMCR- 2009/02/01 -CRDT- 2009/05/15 09:00 -PHST- 2008/12/16 00:00 [received] -PHST- 2009/02/14 00:00 [accepted] -PHST- 2009/05/15 09:00 [entrez] -PHST- 2009/05/15 09:00 [pubmed] -PHST- 2009/08/06 09:00 [medline] -PHST- 2009/02/01 00:00 [pmc-release] -AID - ijerph6020741 [pii] -AID - ijerph-06-00741 [pii] -AID - 10.3390/ijerph6020741 [doi] -PST - ppublish -SO - Int J Environ Res Public Health. 2009 Feb;6(2):741-58. doi: - 10.3390/ijerph6020741. Epub 2009 Feb 20. - -PMID- 17410988 -OWN - NLM -STAT- MEDLINE -DCOM- 20070629 -LR - 20190917 -IS - 0210-4806 (Print) -IS - 0210-4806 (Linking) -VI - 31 -IP - 1 -DP - 2007 Jan -TI - [Acute myocardial infarction associated to the Sildenafil consumption. A case - report and review of the literature]. -PG - 52-7 -AB - Erectile dysfunction affects more than 30 million men in The United States. Since - the FDA approved the use of Sildenafil, prescription of this medication has been - raising. Adverse events of Sildenafil includes: fatigue, dyspnea, and - hypotension. Reported adverse cardiac events associated with the medication use - include myocardial infarction, ventricular tachycardia, angina and death, raising - concerns about the safety of this agent in patients with coronary artery disease. - Published guidelines regarding the management of cardiac patients with erectile - dysfunction suggest that Sildenafil may be hazardous in patients with ischemic - heart disease. In patients using Sildenafil, myocardial infarctions have been - reported to the Food and Drug Administration. Now, we report a patient with - myocardial infarction after taking 100 mg of Sildenafil without sexual activity. -FAU - Velásquez López, J G -AU - Velásquez López JG -AD - Servicio de Urologia Hospital Pablo Tobón Uribe y Universidad CES. - juangvl@gmail.com -FAU - Agudelo Restrepo, C A -AU - Agudelo Restrepo CA -FAU - Yepes Gómez, D -AU - Yepes Gómez D -FAU - Uribe Trujillo, C A -AU - Uribe Trujillo CA -LA - spa -PT - Case Reports -PT - English Abstract -PT - Journal Article -PT - Review -TT - Infarto agudo de miocardio asociado al consumo de sildenafil. Aportación de caso - y revisión de la literatura. -PL - Spain -TA - Actas Urol Esp -JT - Actas urologicas espanolas -JID - 7704993 -RN - 0 (Phosphodiesterase Inhibitors) -RN - 0 (Piperazines) -RN - 0 (Purines) -RN - 0 (Sulfones) -RN - BW9B0ZE037 (Sildenafil Citrate) -SB - IM -MH - Aged -MH - Erectile Dysfunction/drug therapy -MH - Humans -MH - Male -MH - Myocardial Infarction/*chemically induced -MH - Phosphodiesterase Inhibitors/*adverse effects -MH - Piperazines/*adverse effects -MH - Purines/adverse effects -MH - Sildenafil Citrate -MH - Sulfones/*adverse effects -RF - 28 -EDAT- 2007/04/07 09:00 -MHDA- 2007/06/30 09:00 -CRDT- 2007/04/07 09:00 -PHST- 2007/04/07 09:00 [pubmed] -PHST- 2007/06/30 09:00 [medline] -PHST- 2007/04/07 09:00 [entrez] -AID - S0210-4806(07)73595-7 [pii] -AID - 10.1016/s0210-4806(07)73595-7 [doi] -PST - ppublish -SO - Actas Urol Esp. 2007 Jan;31(1):52-7. doi: 10.1016/s0210-4806(07)73595-7. - -PMID- 22519451 -OWN - NLM -STAT- MEDLINE -DCOM- 20130703 -LR - 20190907 -IS - 1873-4294 (Electronic) -IS - 1568-0266 (Linking) -VI - 12 -IP - 10 -DP - 2012 -TI - Novel therapeutic approaches targeting matrix metalloproteinases in - cardiovascular disease. -PG - 1214-21 -AB - Matrix metalloproteinases (MMPs), are proteinases that participate in - extracellular matrix remodelling and degradation. Under normal physiological - conditions, the activities of MMPs are regulated at the level of transcription, - of activation of the pro-MMP precursor zymogens and of inhibition by endogenous - inhibitors (tissue inhibitors of metalloproteinases; TIMPs). Alteration in the - regulation of MMP activity is implicated in atherosclerotic plaque development, - coronary artery disease and heart failure. The pathological effects of MMPs and - TIMPs in cardiovascular diseases involve vascular remodelling, atherosclerotic - plaque instability and left ventricular remodelling after myocardial infarction. - Since excessive tissue remodelling and increased matrix metalloproteinase - activity have been demonstrated during atherosclerotic lesion progression, MMPs - represent a potential target for therapeutic intervention aimed at modification - of vascular pathology by restoring the physiological balance between MMPs and - TIMPs. This review discusses pharmacological approaches to MMP inhibition. -FAU - Briasoulis, Alexandros -AU - Briasoulis A -AD - 1st Cardiology Unit, Hippokration Hospital, Athens University Medical School, - Greece. alexbriasoulis@gmail.com -FAU - Tousoulis, Dimitris -AU - Tousoulis D -FAU - Papageorgiou, Nikolaos -AU - Papageorgiou N -FAU - Kampoli, Anna-Maria -AU - Kampoli AM -FAU - Androulakis, Emmanuel -AU - Androulakis E -FAU - Antoniades, Charalambos -AU - Antoniades C -FAU - Tsiamis, Eleftherios -AU - Tsiamis E -FAU - Latsios, George -AU - Latsios G -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Top Med Chem -JT - Current topics in medicinal chemistry -JID - 101119673 -RN - 0 (Matrix Metalloproteinase Inhibitors) -RN - 0 (Tissue Inhibitor of Metalloproteinases) -RN - EC 3.4.24.- (Matrix Metalloproteinases) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*drug therapy/metabolism -MH - Extracellular Matrix/enzymology -MH - Humans -MH - *Matrix Metalloproteinase Inhibitors -MH - Matrix Metalloproteinases/metabolism -MH - Tissue Inhibitor of Metalloproteinases/metabolism -MH - Ventricular Remodeling -EDAT- 2012/04/24 06:00 -MHDA- 2013/07/05 06:00 -CRDT- 2012/04/24 06:00 -PHST- 2011/08/03 00:00 [received] -PHST- 2011/09/20 00:00 [revised] -PHST- 2011/09/27 00:00 [accepted] -PHST- 2012/04/24 06:00 [entrez] -PHST- 2012/04/24 06:00 [pubmed] -PHST- 2013/07/05 06:00 [medline] -AID - CTMC-EPUB-20120420-011 [pii] -AID - 10.2174/1568026611208011214 [doi] -PST - ppublish -SO - Curr Top Med Chem. 2012;12(10):1214-21. doi: 10.2174/1568026611208011214. - -PMID- 20222816 -OWN - NLM -STAT- MEDLINE -DCOM- 20100607 -LR - 20181201 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Print) -IS - 1477-9072 (Linking) -VI - 8 -IP - 3 -DP - 2010 Mar -TI - Diabetic cardiomyopathy: signaling defects and therapeutic approaches. -PG - 373-91 -LID - 10.1586/erc.10.17 [doi] -AB - Diabetes mellitus is the world's fastest growing disease with high morbidity and - mortality rates, predominantly as a result of heart failure. A significant number - of diabetic patients exhibit diabetic cardiomyopathy; that is, left ventricular - dysfunction independent of coronary artery disease or hypertension. The - pathogenesis of diabetic cardiomyopathy is complex, and is characterized by - dysregulated lipid metabolism, insulin resistance, mitochondrial dysfunction and - disturbances in adipokine secretion and signaling. These abnormalities lead to - impaired calcium homeostasis, ultimately resulting in lusitropic and inotropic - defects. This article discusses the impact of these hallmark factors in diabetic - cardiomyopathy, and concludes with a survey of available and emerging therapeutic - modalities. -FAU - Dobrin, Joseph S -AU - Dobrin JS -AD - Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY - 10029, USA. joseph.dobrin@mssm.edu -FAU - Lebeche, Djamel -AU - Lebeche D -LA - eng -GR - K01 HL076659/HL/NHLBI NIH HHS/United States -GR - R01 HL097357/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -RN - 0 (Adipokines) -RN - 0 (Blood Glucose) -SB - IM -MH - Adipokines/metabolism -MH - Blood Glucose/metabolism -MH - *Calcium Signaling -MH - Cardiomyopathies/drug therapy/etiology/*physiopathology -MH - Diabetes Complications/*diagnosis/drug therapy -MH - Diabetes Mellitus, Type 1/*diagnosis/drug therapy -MH - Diabetes Mellitus, Type 2/*diagnosis/drug therapy -MH - Female -MH - Humans -MH - Insulin Resistance -MH - Lipid Metabolism/physiology -MH - Male -MH - Mitochondria, Heart/metabolism/pathology -MH - Prognosis -MH - Risk Assessment -PMC - PMC5137585 -MID - NIHMS831818 -EDAT- 2010/03/13 06:00 -MHDA- 2010/06/09 06:00 -PMCR- 2016/12/05 -CRDT- 2010/03/13 06:00 -PHST- 2010/03/13 06:00 [entrez] -PHST- 2010/03/13 06:00 [pubmed] -PHST- 2010/06/09 06:00 [medline] -PHST- 2016/12/05 00:00 [pmc-release] -AID - 10.1586/erc.10.17 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2010 Mar;8(3):373-91. doi: 10.1586/erc.10.17. - -PMID- 23563656 -OWN - NLM -STAT- MEDLINE -DCOM- 20130724 -LR - 20240109 -IS - 0171-2004 (Print) -IS - 0171-2004 (Linking) -IP - 216 -DP - 2013 -TI - Cardiovascular effects of sphingosine-1-phosphate (S1P). -PG - 147-70 -LID - 10.1007/978-3-7091-1511-4_8 [doi] -AB - Sphingosine-1-phosphate (S1P) regulates important functions in cardiac and - vascular homeostasis. It has been implied to play causal roles in the - pathogenesis of many cardiovascular disorders such as coronary artery disease, - atherosclerosis, myocardial infarction, and heart failure. The majority of S1P in - plasma is associated with high-density lipoproteins (HDL), and their S1P content - has been shown to be responsible, at least in part, for several of the beneficial - effects of HDL on cardiovascular risk. The attractiveness of S1P-based drugs for - potential cardiovascular applications is increasing in the wake of the clinical - approval of FTY720, but answers to important questions on the effects of S1P in - cardiovascular biology and medicine must still be found. This chapter focuses on - the current understanding of the role of S1P and its receptors in cardiovascular - physiology, pathology, and disease. -FAU - Levkau, Bodo -AU - Levkau B -AD - University of Duisburg-Essen, Essen, Germany. bodo.levkau@uni-due.de -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Handb Exp Pharmacol -JT - Handbook of experimental pharmacology -JID - 7902231 -RN - 0 (Cardiovascular Agents) -RN - 0 (Lipoproteins, HDL) -RN - 0 (Lysophospholipids) -RN - 26993-30-6 (sphingosine 1-phosphate) -RN - NGZ37HRE42 (Sphingosine) -SB - IM -MH - Animals -MH - Cardiovascular Agents/therapeutic use -MH - Cardiovascular Diseases/drug therapy/*metabolism/physiopathology -MH - Cardiovascular System/drug effects/*metabolism/physiopathology -MH - Drug Design -MH - Hemodynamics -MH - Humans -MH - Lipoproteins, HDL/metabolism -MH - Lysophospholipids/*metabolism/therapeutic use -MH - *Signal Transduction/drug effects -MH - Sphingosine/*analogs & derivatives/metabolism/therapeutic use -EDAT- 2013/04/09 06:00 -MHDA- 2013/07/25 06:00 -CRDT- 2013/04/09 06:00 -PHST- 2013/04/09 06:00 [entrez] -PHST- 2013/04/09 06:00 [pubmed] -PHST- 2013/07/25 06:00 [medline] -AID - 10.1007/978-3-7091-1511-4_8 [doi] -PST - ppublish -SO - Handb Exp Pharmacol. 2013;(216):147-70. doi: 10.1007/978-3-7091-1511-4_8. - -PMID- 17110239 -OWN - NLM -STAT- MEDLINE -DCOM- 20070125 -LR - 20061119 -IS - 0272-2712 (Print) -IS - 0272-2712 (Linking) -VI - 26 -IP - 4 -DP - 2006 Dec -TI - Postprandial lipemia and remnant lipoproteins. -PG - 773-86 -AB - Increased postprandial lipemia or elevated levels of triglyceride-rich remnant - lipoproteins in fasting plasma are associated with increased risk of coronary - artery disease. Despite many studies showing that postprandial triglyceride-rich - lipoproteins play a central role in the pathogenesis of atherosclerosis, suitably - standardized methods to measure postprandial lipemia or remnant lipoproteins in - the clinical setting are lacking. This approach for cardiovascular risk - assessment is confined to research laboratories and for the time being is not a - standard procedure in clinical practice. -FAU - Cohn, Jeffrey S -AU - Cohn JS -AD - Nutrition and Metabolism Group, Heart Research Institute, 114 Pyrmont Bridge - Road, Camperdown, NSW 2050, Australia. cohnj@hri.org.au -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Lab Med -JT - Clinics in laboratory medicine -JID - 8100174 -RN - 0 (Dietary Fats) -RN - 0 (Triglycerides) -SB - IM -MH - Atherosclerosis/*blood/etiology -MH - Dietary Fats/*metabolism -MH - Fasting/*blood/metabolism -MH - Humans -MH - Hyperlipidemias/*metabolism -MH - Postprandial Period/*physiology -MH - Risk Assessment -MH - Triglycerides/*blood -RF - 89 -EDAT- 2006/11/18 09:00 -MHDA- 2007/01/26 09:00 -CRDT- 2006/11/18 09:00 -PHST- 2006/11/18 09:00 [pubmed] -PHST- 2007/01/26 09:00 [medline] -PHST- 2006/11/18 09:00 [entrez] -AID - S0272-2712(06)00073-4 [pii] -AID - 10.1016/j.cll.2006.07.003 [doi] -PST - ppublish -SO - Clin Lab Med. 2006 Dec;26(4):773-86. doi: 10.1016/j.cll.2006.07.003. - -PMID- 19645208 -OWN - NLM -STAT- MEDLINE -DCOM- 20090821 -LR - 20161020 -IS - 1122-0643 (Print) -IS - 1122-0643 (Linking) -VI - 72 -IP - 1 -DP - 2009 Mar -TI - Additive beneficial effects of beta blockers in the prevention of symptomatic - heart failure. -PG - 18-22 -AB - The prevention of symptomatic heart failure represents the treatment of patients - in the A and B stages of AHA/ACC heart failure classification. Stage A refers to - patients without structural heart disease but at risk to develop chronic heart - failure. The major risk factors in stage A are hypertension, diabetes, - atherosclerosis, family history of coronary artery disease and history of - cardiotoxic drug use. In this stage, blockers hypertension is the primary area in - which beta blockers may be useful. Beta blockers seem not to be superior to other - medication in reducing the development of heart failure due to hypertension. - Stage B heart failure refers to structural heart disease but without symptoms of - heart failure. This includes patients with asymptomatic valvular disease, - asymptomatic left ventricular (LV) dysfunction, previous myocardial infarction - with or without LV dysfunction. In asymptomatic valvular disease no data are - available on the efficacy of beta blockers to prevent heart failure. In - asymptomatic LV dysfunction only few asymptomatic patients have been enrolled in - the trials which tested beta blockers. NYHA I patients were barely 228 in the - MDC, MERIT and ANZ trials altogether. The REVERT trial was the only trial - focusing on NYHA I patients with LV ejection fraction less than 40%. Metoprolol - extended release on top of ACE inhibitors ameliorated LV systolic volume and - ejection fraction. A post hoc analysis of the SOLVD Prevention trial demonstrated - that beta blockers reduced death and development of heart failure. Similar - results were reported in post MI patients in a post hoc analysis of the SAVE - trial (Asymptomatic LV failure post myocardial infarction). In the CAPRICORN - trial about 65% of the patients were not taking diuretics and then could be - considered asymptomatic. The study revealed a reduction in mortality and a - non-significant trend toward reduction of death and hospital admission for heart - failure. CONCLUSIONS: beta blockers are not specifically indicated in stage A - heart failure. On the contrary, in most of the stage B patients, and particularly - after MI, beta blockers are indicated to reduce mortality and, probably, also the - progression toward symptomatic heart failure. -FAU - Genovesi Ebert, Alberto -AU - Genovesi Ebert A -AD - Cardiologia, Spedali Riuniti, Livorno, Italy. a.genovesi@tin.it -FAU - Colivicchi, Furio -AU - Colivicchi F -FAU - Malvezzi Caracciolo, Marco -AU - Malvezzi Caracciolo M -FAU - Riccio, Carmine -AU - Riccio C -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Monaldi Arch Chest Dis -JT - Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace -JID - 9307314 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Diuretics) -SB - IM -MH - Adrenergic beta-Antagonists/*therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Calcium Channel Blockers/therapeutic use -MH - Disease Progression -MH - Diuretics/therapeutic use -MH - Drug Therapy, Combination -MH - Heart Failure/diagnosis/etiology/*prevention & control -MH - Humans -MH - Myocardial Infarction/complications/drug therapy -MH - Severity of Illness Index -MH - Treatment Outcome -MH - Ventricular Dysfunction, Left/etiology/prevention & control -RF - 36 -EDAT- 2009/08/04 09:00 -MHDA- 2009/08/22 09:00 -CRDT- 2009/08/04 09:00 -PHST- 2009/08/04 09:00 [entrez] -PHST- 2009/08/04 09:00 [pubmed] -PHST- 2009/08/22 09:00 [medline] -AID - 10.4081/monaldi.2009.338 [doi] -PST - ppublish -SO - Monaldi Arch Chest Dis. 2009 Mar;72(1):18-22. doi: 10.4081/monaldi.2009.338. - -PMID- 21538911 -OWN - NLM -STAT- MEDLINE -DCOM- 20110919 -LR - 20151119 -IS - 1862-8354 (Electronic) -IS - 1862-8346 (Linking) -VI - 5 -IP - 5-6 -DP - 2011 Jun -TI - Vascular proteomics and the discovery process of clinical biomarkers: The case of - TWEAK. -PG - 281-8 -LID - 10.1002/prca.201000102 [doi] -AB - In the last years, big efforts are devoted to the search of novel biomarkers. - Proteomic approaches in healthy and pathological samples may help us to discern - differential protein expression patterns. These identified proteins include - potential culprits in pathological pathways and/or clinical biomarkers to - identify individuals at risk. However, extensively validation must be carried out - before their implementation into the clinical practice. Biomarkers need to - discriminate between health and disease, detect preclinical disease stages, have - impact on survival prediction, and add predictive value beyond traditional risk - factors and global risk algorithms. Now, we summarize the data of soluble tumor - necrosis factor-like weak inducer of apoptosis (sTWEAK), a new cardiovascular - biomarker identified by proteomic analysis. Decreased sTWEAK concentrations have - been shown in patients with carotid atherosclerosis, coronary artery disease, - congestive heart failure, peripheral artery disease, or chronic kidney disease - (CKD). sTWEAK predicted adverse outcomes in patients with heart failure, - myocardial infarction, and CKD. Finally, different drug regimens were able to - modify sTWEAK plasma levels in patients with CKD. Although sTWEAK seems so far to - fulfill the requisites in the development of a new biomarker, more large-scale - studies are warranted to consolidate its usefulness. -CI - Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. -FAU - Blanco-Colio, Luis M -AU - Blanco-Colio LM -AD - Renal and Vascular Research Lab, IIS-Fundación Jimenez Díaz, Autónoma University, - Madrid, Spain. lblanco@fjd.es -FAU - Martín-Ventura, Jose L -AU - Martín-Ventura JL -FAU - Carrero, Juan J -AU - Carrero JJ -FAU - Yilmaz, Mahmut I -AU - Yilmaz MI -FAU - Moreno, Juan A -AU - Moreno JA -FAU - Gómez-Guerrero, Carmen -AU - Gómez-Guerrero C -FAU - Ortiz, Alberto -AU - Ortiz A -FAU - Egido, Jesús -AU - Egido J -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110428 -PL - Germany -TA - Proteomics Clin Appl -JT - Proteomics. Clinical applications -JID - 101298608 -RN - 0 (Biomarkers) -RN - 0 (Tumor Necrosis Factor-alpha) -SB - IM -MH - *Apoptosis -MH - Biomarkers/chemistry/metabolism -MH - Blood Vessels/*metabolism/*pathology -MH - Cardiovascular Diseases/diagnosis/metabolism/pathology/therapy -MH - Humans -MH - Proteomics/*methods -MH - Tumor Necrosis Factor-alpha/*chemistry/*metabolism -EDAT- 2011/05/04 06:00 -MHDA- 2011/09/20 06:00 -CRDT- 2011/05/04 06:00 -PHST- 2010/09/29 00:00 [received] -PHST- 2011/01/19 00:00 [revised] -PHST- 2011/01/20 00:00 [accepted] -PHST- 2011/05/04 06:00 [entrez] -PHST- 2011/05/04 06:00 [pubmed] -PHST- 2011/09/20 06:00 [medline] -AID - 10.1002/prca.201000102 [doi] -PST - ppublish -SO - Proteomics Clin Appl. 2011 Jun;5(5-6):281-8. doi: 10.1002/prca.201000102. Epub - 2011 Apr 28. - -PMID- 20048439 -OWN - NLM -STAT- MEDLINE -DCOM- 20100429 -LR - 20100105 -IS - 0917-5857 (Print) -IS - 0917-5857 (Linking) -VI - 20 -IP - 1 -DP - 2010 Jan -TI - [Calcium antagonists: current and future applications based on new evidence. - Cardio-protective effect of calcium antagonists]. -PG - 89-93 -AB - Calcium antagonists block calcium influx through the L-type calcium channel to - produce dilatation of resistant arteries including coronary arteries. Due to - arterial vasodilatation, calcium antagonists have beneficial effects for ischemic - heart disease, left ventricular hypertrophy and heart failure. Some of calcium - antagonists are known to have the inhibitory action for T-type or N-type calcium - channel which might be beneficial for the inhibition of reactive tachycardia. - Calcium antagonists may also retard the progression of atherosclerosis to prevent - cardiovascular events. -FAU - Hongo, Kenichi -AU - Hongo K -AD - Division of Cardiology, The Jikei University School of Medicine, Japan. -FAU - Yoshimura, Michihiro -AU - Yoshimura M -LA - jpn -PT - English Abstract -PT - Journal Article -PT - Review -PL - Japan -TA - Clin Calcium -JT - Clinical calcium -JID - 9433326 -RN - 0 (Calcium Channel Blockers) -RN - 0 (Calcium Channels, L-Type) -RN - 0 (Calcium Channels, N-Type) -RN - 0 (Calcium Channels, T-Type) -RN - 0 (Dihydropyridines) -SB - IM -MH - Atherosclerosis/prevention & control -MH - Calcium Channel Blockers/*pharmacology/*therapeutic use -MH - Calcium Channels, L-Type -MH - Calcium Channels, N-Type -MH - Calcium Channels, T-Type -MH - Dihydropyridines/*pharmacology/*therapeutic use -MH - Heart/drug effects -MH - Heart Failure/*prevention & control -MH - Humans -MH - Hypertrophy, Left Ventricular/*prevention & control -MH - Muscle, Smooth, Vascular/drug effects -MH - Myocardial Ischemia/*prevention & control -RF - 21 -EDAT- 2010/01/06 06:00 -MHDA- 2010/04/30 06:00 -CRDT- 2010/01/06 06:00 -PHST- 2010/01/06 06:00 [entrez] -PHST- 2010/01/06 06:00 [pubmed] -PHST- 2010/04/30 06:00 [medline] -AID - 10018993 [pii] -PST - ppublish -SO - Clin Calcium. 2010 Jan;20(1):89-93. - -PMID- 19104798 -OWN - NLM -STAT- MEDLINE -DCOM- 20090526 -LR - 20211020 -IS - 1619-7089 (Electronic) -IS - 1619-7070 (Linking) -VI - 36 Suppl 1 -DP - 2009 Mar -TI - PET and MRI in cardiac imaging: from validation studies to integrated - applications. -PG - S121-30 -LID - 10.1007/s00259-008-0980-1 [doi] -AB - INTRODUCTION: Positron emission tomography (PET) is the gold standard for - non-invasive assessment of myocardial viability and allows accurate detection of - coronary artery disease by assessment of myocardial perfusion. Magnetic resonance - imaging (MRI) provides high resolution anatomical images that allow accurate - evaluation of ventricular structure and function together with detection of - myocardial infarction. OBJECTIVE: Potential hybrid PET/MR tomography may - potentially facilitate the combination of information from these imaging - modalities in cardiology. Furthermore, the combination of anatomical MRI images - with the high sensitivity of PET for detecting molecular targets may extent the - application of these modalities to the characterization of atherosclerotic - plaques and to the evaluation of angiogenetic or stem cell therapies, for - example. DISCUSSION: This article reviews studies using MRI and PET in parallel - to compare their performance in cardiac applications together with the potential - benefits and applications provided by hybrid PET/MRI systems. -FAU - Nekolla, Stephan G -AU - Nekolla SG -AD - Nuklearmedizinische Klinik und Poliklinik, Technischen Universität München, - München, Germany. s.nekolla@lrz.tu-muenchen.de -FAU - Martinez-Moeller, Axel -AU - Martinez-Moeller A -FAU - Saraste, Antti -AU - Saraste A -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Germany -TA - Eur J Nucl Med Mol Imaging -JT - European journal of nuclear medicine and molecular imaging -JID - 101140988 -SB - IM -MH - Animals -MH - Heart/*diagnostic imaging -MH - Heart Diseases/diagnosis/diagnostic imaging -MH - Humans -MH - Image Processing, Computer-Assisted -MH - Magnetic Resonance Imaging/*methods -MH - Positron-Emission Tomography/*methods -MH - *Validation Studies as Topic -RF - 58 -EDAT- 2008/12/24 09:00 -MHDA- 2009/05/27 09:00 -CRDT- 2008/12/24 09:00 -PHST- 2008/12/24 09:00 [entrez] -PHST- 2008/12/24 09:00 [pubmed] -PHST- 2009/05/27 09:00 [medline] -AID - 10.1007/s00259-008-0980-1 [doi] -PST - ppublish -SO - Eur J Nucl Med Mol Imaging. 2009 Mar;36 Suppl 1:S121-30. doi: - 10.1007/s00259-008-0980-1. - -PMID- 21875509 -OWN - NLM -STAT- MEDLINE -DCOM- 20111024 -LR - 20130502 -IS - 1873-1740 (Electronic) -IS - 0033-0620 (Linking) -VI - 54 -IP - 2 -DP - 2011 Sep-Oct -TI - Old and new intravenous inotropic agents in the treatment of advanced heart - failure. -PG - 97-106 -LID - 10.1016/j.pcad.2011.03.011 [doi] -AB - Inotropic agents are administered to improve cardiac output and peripheral - perfusion in patients with systolic dysfunction and low cardiac output. However, - there is evidence of increased mortality and adverse effects associated with - current inotropic agents. These adverse outcomes may be ascribed to patient - selection, increased myocardial energy expenditure and oxygen consumption, or to - specific mechanisms of action. Both sympathomimetic amines and type III - phosphodiesterase inhibitors act through an increase in intracellular cyclic - adenosine monophoshate and free calcium concentrations, mechanisms that increase - oxygen consumption and favor arrhythmias. Concomitant peripheral vasodilation - with some agents (phosphodiesterase inhibitors and levosimendan) may also lower - coronary perfusion pressure and favor myocardial damage. New agents with - different mechanisms of action might have a better benefit to risk ratio and - allow an improvement in tissue and end-organ perfusion with less untoward - effects. We have summarized the characteristics of the main inotropic agents for - heart failure treatment, the data from randomized controlled trials, and future - perspectives for this class of drugs. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Metra, Marco -AU - Metra M -AD - Cardiology, Department of Experimental and Applied Medicine, University of - Brescia, Civil Hospital of Brescia, Italy. metramarco@libero.it -FAU - Bettari, Luca -AU - Bettari L -FAU - Carubelli, Valentina -AU - Carubelli V -FAU - Cas, Livio Dei -AU - Cas LD -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Prog Cardiovasc Dis -JT - Progress in cardiovascular diseases -JID - 0376442 -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Cardiac Output/drug effects -MH - Cardiotonic Agents/*administration & dosage/adverse effects -MH - Disease Progression -MH - Evidence-Based Medicine -MH - Heart Failure/*drug therapy/physiopathology -MH - Humans -MH - Infusions, Intravenous -MH - Risk Assessment -MH - Risk Factors -MH - Treatment Outcome -EDAT- 2011/08/31 06:00 -MHDA- 2011/10/25 06:00 -CRDT- 2011/08/31 06:00 -PHST- 2011/08/31 06:00 [entrez] -PHST- 2011/08/31 06:00 [pubmed] -PHST- 2011/10/25 06:00 [medline] -AID - S0033-0620(11)00066-1 [pii] -AID - 10.1016/j.pcad.2011.03.011 [doi] -PST - ppublish -SO - Prog Cardiovasc Dis. 2011 Sep-Oct;54(2):97-106. doi: 10.1016/j.pcad.2011.03.011. - -PMID- 19192988 -OWN - NLM -STAT- MEDLINE -DCOM- 20090414 -LR - 20190911 -IS - 1473-4877 (Electronic) -IS - 0300-7995 (Linking) -VI - 25 -IP - 2 -DP - 2009 Feb -TI - Perspectives on low-density lipoprotein cholesterol goal achievement. -PG - 431-47 -LID - 10.1185/03007990802631438 [doi] -AB - BACKGROUND: Elevated levels of low-density lipoprotein cholesterol (LDL-C) are - associated with an increased risk of coronary heart disease (CHD). European and - US guidelines now recommend lower LDL-C levels, particularly in high-risk - patients. Although LDL-C treatment goals to reduce the risk of CHD are clear, - many patients do not reach their LDL-C goals. OBJECTIVES: Examine consensus - guideline targets for LDL-C lowering in patients at high or very high - cardiovascular risk; examine cholesterol goal achievement in clinical practice; - evaluate the effectiveness of ezetimibe/statin and other adjunctive - lipid-lowering treatments in achieving LDL-C goals; and consider ongoing - controversies and the randomized controlled trials that may help to resolve or - better illuminate them. METHODS: An English-language PubMed search was conducted - to identify prospective randomized controlled trials, open-label studies, and - retrospective and observational studies from 2001 (same year that the executive - summary of the National Cholesterol Education Program's Adult Treatment Panel III - was published) to present for an analysis of the effects of adjunctive therapies - on LDL-C lowering and goal attainment in patients at elevated cardiovascular - risk. RESULTS: Elevated LDL-C is the primary target of lipid-lowering therapy; - aggressive lowering is of great benefit to those at high risk. Statins are - recommended first-line lipid-lowering agents, with a long, well-regarded history - of efficacy and safety. Not all patients, however, can achieve recommended LDL-C - goals simply using starting doses of statins. For such patients, more intensive - therapy utilizing high-dose statins or combination therapy, including statins - combined with other lipid-lowering agents, such as ezetimibe, bile acid resins - (BARs), or niacin, is warranted. Potential limitations of the present review - include possible publication bias and the focus on pharmacotherapy rather than - lifestyle modification and the important objective of multiple risk-factor - modification to reduce absolute global cardiovascular risk. CONCLUSIONS: With a - well-established link between elevated LDL-C and cardiovascular risk, aggressive - LDL-C lowering becomes particularly important. Patients needing intensive LDL-C - lowering to achieve goals will often require adjunctive treatments, including - ezetimibe, BARs, or niacin along with statins. Given both their high mg: mg - potency in lowering LDL-C and favorable tolerability and patient - acceptance/adherence profile, ezetimibe/statin combination regimens arguably - provide the greatest likelihood for patients to reach new, lower LDL-C targets; - however, efficacy and safety data of any adjunctive treatment, along with drug - costs and patient adherence to treatment (partly related to complexity of the - regimen) all need to be considered when determining the optimal regimen to - achieve LDL-C goals in individual patients according to their baseline absolute - cardiovascular risk, LDL-C level, and consensus LDL-C targets. -FAU - Catapano, Alberico L -AU - Catapano AL -AD - Marie Curie Training Centre for Cardiovascular Diseases, University of Milan, - Milan, Italy. Alberico.Catapano@unimi.it -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Curr Med Res Opin -JT - Current medical research and opinion -JID - 0351014 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Cholesterol, LDL) -SB - IM -MH - Anticholesteremic Agents/administration & dosage/therapeutic use -MH - Cholesterol, LDL/*blood -MH - Drug Therapy, Combination -MH - Europe -MH - Humans -MH - *Practice Guidelines as Topic -MH - United Kingdom -MH - United States -RF - 99 -EDAT- 2009/02/06 09:00 -MHDA- 2009/04/15 09:00 -CRDT- 2009/02/06 09:00 -PHST- 2009/02/06 09:00 [entrez] -PHST- 2009/02/06 09:00 [pubmed] -PHST- 2009/04/15 09:00 [medline] -AID - 10.1185/03007990802631438 [pii] -AID - 10.1185/03007990802631438 [doi] -PST - ppublish -SO - Curr Med Res Opin. 2009 Feb;25(2):431-47. doi: 10.1185/03007990802631438. - -PMID- 16918274 -OWN - NLM -STAT- MEDLINE -DCOM- 20061006 -LR - 20131121 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Linking) -VI - 4 -IP - 4 -DP - 2006 Jul -TI - Bone marrow cells for cardiac regeneration and repair: current status and issues. -PG - 557-68 -AB - Extensive studies in experimental animal heart models and patients have shown the - promise of bone marrow cell (BMC) transplantation as an alternative strategy to - the conventional treatment modalities for cardiac repair. 'Stemness' of BMC to - adopt cardiac phenotype, their potential as carriers of exogenous therapeutic - genes and an inherent ability to express growth factors and cytokines to exert - paracrine effects have been especially focused until recently. These findings - suggest that locally delivered BMCs are capable of regenerating de novo - myocardium. Others have shown that extensive neovascularization due to paracrine - effects of the engrafted cells resulted in improved regional blood flow and - reduced infarct size. Despite initial success, there are multiple fundamental - issues that remain contentious. Indeed, resolving these issues will optimize - future heart cell therapy protocols to achieve better prognosis in the clinical - settings. This review is a concise, in-depth and critical appreciation of the - role of BMCs in heart cell therapy and builds a conceptual framework to elaborate - their significance as a possible source of donor cells. Moreover, it discusses - the current status of BMC transplantation as a clinical modality and the relevant - issues confronting this approach in light of the published data with clinical - relevance. -FAU - Haider, Husnain Kh -AU - Haider HKh -AD - Department of Pathology and Laboratory of Medicine, 231-Albert Sabinway, - Cinncinati, OH 45267-0529, USA. haiderkh@ucmail.uc.edu -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -RN - 0 (Antigens, CD34) -RN - 0 (Antimetabolites, Antineoplastic) -RN - M801H13NRU (Azacitidine) -SB - IM -MH - Animals -MH - Antigens, CD34/physiology -MH - Antimetabolites, Antineoplastic/pharmacology -MH - Azacitidine/pharmacology -MH - Bone Marrow Cells/*physiology -MH - Bone Marrow Transplantation -MH - Cell Differentiation/physiology -MH - Cell Movement -MH - Cells, Cultured -MH - Coronary Artery Bypass -MH - Disease Models, Animal -MH - Humans -MH - Myocytes, Cardiac/physiology -MH - Phenotype -MH - Regeneration/*physiology -MH - Ventricular Dysfunction, Left/therapy -RF - 82 -EDAT- 2006/08/22 09:00 -MHDA- 2006/10/07 09:00 -CRDT- 2006/08/22 09:00 -PHST- 2006/08/22 09:00 [pubmed] -PHST- 2006/10/07 09:00 [medline] -PHST- 2006/08/22 09:00 [entrez] -AID - 10.1586/14779072.4.4.557 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2006 Jul;4(4):557-68. doi: 10.1586/14779072.4.4.557. - -PMID- 16824807 -OWN - NLM -STAT- MEDLINE -DCOM- 20061201 -LR - 20060728 -IS - 1567-5688 (Print) -IS - 1567-5688 (Linking) -VI - 7 -IP - 4 -DP - 2006 Aug -TI - Is insulin resistance atherogenic? A review of the evidence. -PG - 5-10 -AB - Several factors that increase the risk of cardiovascular disease tend to cluster - together in the same individual. Insulin resistance is believed to be a - pathophysiological disturbance that underlies many of the risk factors. Whether - insulin resistance per se is a cardiovascular risk factor is uncertain. Insulin - resistance of myocardial muscle has been documented both in patients with type 2 - diabetes and in nondiabetic subjects with angiographically proven coronary artery - disease. In addition, in diabetic patients there is a mismatch between the - redistribution of blood flow and glucose uptake during insulinization. Finally, - the endothelial dysfunction and the hyperinsulinemia that accompany insulin - resistance may adversely affect myocardial function. The evidence from - epidemiological studies or clinical trials is, however, mixed. In at least one - recent prospective study in patients with congestive heart failure, insulin - resistance was an independent predictor of cardiac death. Conclusive proof would - require a prospective study in which insulin resistance is measured directly and - adequate account is taken of the classical cardiovascular risk factors. -FAU - Ferrannini, Ele -AU - Ferrannini E -AD - Department of Internal Medicine, Via Roma 67, 56126 Pisa, Italy. - ferranni@ifc.cnr.it -FAU - Iozzo, Patricia -AU - Iozzo P -LA - eng -PT - Journal Article -PT - Review -DEP - 20060707 -PL - Netherlands -TA - Atheroscler Suppl -JT - Atherosclerosis. Supplements -JID - 100973461 -SB - IM -MH - *Cardiovascular Diseases/epidemiology/etiology/physiopathology -MH - Diabetes Mellitus, Type 2/complications/epidemiology/physiopathology -MH - Endothelium, Vascular/physiopathology -MH - Heart/physiopathology -MH - Humans -MH - *Insulin Resistance -MH - Myocardium/metabolism -MH - Risk -MH - Risk Factors -RF - 24 -EDAT- 2006/07/11 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/07/11 09:00 -PHST- 2006/07/11 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/07/11 09:00 [entrez] -AID - S1567-5688(06)00045-6 [pii] -AID - 10.1016/j.atherosclerosissup.2006.05.006 [doi] -PST - ppublish -SO - Atheroscler Suppl. 2006 Aug;7(4):5-10. doi: - 10.1016/j.atherosclerosissup.2006.05.006. Epub 2006 Jul 7. - -PMID- 16522931 -OWN - NLM -STAT- MEDLINE -DCOM- 20060724 -LR - 20250623 -IS - 0731-5724 (Print) -IS - 0731-5724 (Linking) -VI - 25 -IP - 1 -DP - 2006 Feb -TI - Phytosterols/stanols lower cholesterol concentrations in familial - hypercholesterolemic subjects: a systematic review with meta-analysis. -PG - 41-8 -AB - BACKGROUND: To-date, reviews regarding the cholesterol lowering capacity of - phytosterols/stanols have focused on normo- and hypercholesterolemic (HC) - subjects. Familial hypercholestrolemia (FH) is characterized by very high - low-density lipoprotein cholesterol (LDL-C) concentrations and is considered a - world public health problem due to the high incidence of premature coronary heart - disease (CHD) in these patients. OBJECTIVE: To conduct a systematic review that - investigates the efficacy of phytosterols/stanols in lowering total cholesterol - (TC) and LDL-C concentrations in FH subjects. DESIGN: Randomized controlled - intervention trials with the primary objective to investigate the effects of - phytosterols/stanols on lipid concentrations in FH subjects were identified - through selected international journal databases and reference lists of relevant - publications. Two researchers extracted data from each identified trial and only - trials of sufficient quality (e.g. controlled, randomized, double-blind, good - compliance, sufficient statistical power) were included in the review. The main - outcome measures were differences between treatment and control groups for LDL-C, - TC, high-density lipoprotein cholesterol (HDL-C) and triacylglycerol (TG). - RESULTS: Six out of 13 studies were of sufficient quality. Two were excluded from - the meta-analysis because the sterols were administered in the granulate form at - very high dosages (12 g/day and 24 g/day) compared to the other studies that used - fat spreads as vehicle with dosages ranging from 1.6-2.8 g/day. The subjects were - heterozygous, aged 2-69 years with baseline TC and LDL-C concentrations of +/-7 - mmol/L and +/-5.4 mmol/L, respectively. The duration of the studies ranged from 4 - weeks to 3 months. Fat spreads enriched with 2.3 +/- 0.5 g phytosterols/stanols - per day significantly reduced TC from 7 to 11% with a mean decrease of 0.65 - mmol/L [95% CI -0.88, -0.42 mmol/L], p < 0.00001 and LDL-C from 10-15% with a - mean decrease of 0.64 mmol/L [95% CI -0.86, -0.43 mmol/L], p < 0.00001 in 6.5 +/- - 1.9 weeks compared to control treatment, without any adverse effects. TG and - HDL-C concentrations were not affected. CONCLUSION: Phytosterols/stanols may - offer an effective adjunct to the cholesterol lowering treatment strategy of FH - patients. -FAU - Moruisi, Kgomotso G -AU - Moruisi KG -AD - School of Physiology, Nutrition and Consumer Science, North-West University, - Private Bag X6001 (Internal box 594), Potchefstroom, 2520, South Africa. -FAU - Oosthuizen, Welma -AU - Oosthuizen W -FAU - Opperman, Anna M -AU - Opperman AM -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -PL - United States -TA - J Am Coll Nutr -JT - Journal of the American College of Nutrition -JID - 8215879 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Cholesterol, LDL) -RN - 0 (Dietary Fats) -RN - 0 (Phytosterols) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Adolescent -MH - Adult -MH - Aged -MH - Anticholesteremic Agents/*therapeutic use -MH - Child -MH - Child, Preschool -MH - Cholesterol/*blood -MH - Cholesterol, LDL/*blood -MH - Dietary Fats/administration & dosage -MH - Female -MH - Food, Fortified -MH - Humans -MH - Hyperlipoproteinemia Type II/*drug therapy -MH - Male -MH - Middle Aged -MH - Phytosterols/*therapeutic use -MH - Treatment Outcome -RF - 43 -EDAT- 2006/03/09 09:00 -MHDA- 2006/07/25 09:00 -CRDT- 2006/03/09 09:00 -PHST- 2006/03/09 09:00 [pubmed] -PHST- 2006/07/25 09:00 [medline] -PHST- 2006/03/09 09:00 [entrez] -AID - 25/1/41 [pii] -AID - 10.1080/07315724.2006.10719513 [doi] -PST - ppublish -SO - J Am Coll Nutr. 2006 Feb;25(1):41-8. doi: 10.1080/07315724.2006.10719513. - -PMID- 21299928 -OWN - NLM -STAT- MEDLINE -DCOM- 20110602 -LR - 20110208 -IS - 1603-9629 (Electronic) -IS - 0907-8916 (Linking) -VI - 58 -IP - 2 -DP - 2011 Feb -TI - New physiological effects of the incretin hormones GLP-1 and GIP. -PG - B4248 -AB - With approximately 400 million people worldwide today being obese, we are facing - a major public health problem due to the increasing prevalence of the related - comorbidities such as type 2 diabetes, hypertension and coronary heart disease. - To date, pharmacological treatment of obesity has been largely unsuccessful, only - achieving modest and short-lasting reductions in body weight and with adverse - effects. Scientific interest in recent years has concentrated on both the - secretion and function of the incretin hormones, GLP-1 and GIP, and their - suitability as new target drugs. The potential of GLP-1 to reduce gastric - emptying, appetite and food intake makes it an attractive tool in the fight - against obesity and several companies are developing weight lowering drugs based - on GLP-1. Currently, it is not known whether the inhibiting effects of GLP-1 on - gastric emptying, appetite and food intake are directly mediated by GLP-1, or if - the effects are secondary to the robust insulin responses, and thereby amylin - responses, elicited by GLP-1. The first study aimed to further elucidate the - mechanisms of these effects in order to strengthen the development of - anti-diabetic drugs with potential weight lowering capabilities. We found that - GLP-1 mediates its effect on gastrointestinal motility, appetite, food intake and - glucagon secretion directly and thereby in an amylin-independent fashion. In - vitro and animal studies indicate that GIP exerts direct effects on adipose - tissue and lipid metabolism, promoting fat deposition. Due to its therapeutic - potential in obesity treatment, a rapidly increasing number of functional studies - are investigating effects of acute and chronic loss of GIP signaling in glucose - and lipid homeostasis. However, the physiological significance of GIP as a - regulator of lipid metabolism in humans remains unclear. In the second study, we - investigated the effects of GIP on the removal rate of plasma TAG and FFA - concentrations, which were increased after either a mixed meal or infusion of - Intralipid and insulin. Under these experimental conditions, we were not able to - demonstrate any effects of GIP on the removal rate of either chylomicron-TAG or - Intralipid-derived TAG concentrations. However, we found evidence for enhanced - FFA re-esterification under conditions with combined high GIP and insulin - concentrations. Based on findings from this study, the third study was designed - to evaluate the direct effects of GIP on regional adipose tissue and splanchnic - metabolism. Regional net substrate fluxes across the subcutaneous, abdominal - adipose tissue and the splanchnic tissues were examined by direct measurements of - arterio-venous concentration differences of various metabolites in combination - with regional blood flow measurements (Fick's principle). GIP in combination with - hyperinsulinemia and hyperglycemia increased blood flow, glucose uptake, and FFA - re-esterification, resulting in increased TAG deposition in abdominal, - subcutaneous adipose tissue. Finally, it was not possible to demonstrate any - effect of GIP per se on net lipid metabolism in the splanchnic area either during - fasting conditions or in combination with hyperinsulinemia and hyperglycemia. -FAU - Asmar, Meena -AU - Asmar M -AD - Department of Biomedical Sciences, The Panum Institute, University of Copenhagen, - Denmark. masmar@mfi.ku.dk -LA - eng -PT - Journal Article -PT - Review -PL - Denmark -TA - Dan Med Bull -JT - Danish medical bulletin -JID - 0066040 -RN - 0 (Incretins) -RN - 0 (Islet Amyloid Polypeptide) -RN - 59392-49-3 (Gastric Inhibitory Polypeptide) -RN - 89750-14-1 (Glucagon-Like Peptide 1) -RN - 9007-92-5 (Glucagon) -SB - IM -MH - Adult -MH - Appetite/drug effects/*physiology -MH - Eating -MH - Gastric Emptying/*physiology -MH - Gastric Inhibitory Polypeptide/*physiology -MH - Glucagon/physiology -MH - Glucagon-Like Peptide 1/*physiology -MH - Humans -MH - Incretins/*physiology -MH - Islet Amyloid Polypeptide/physiology -MH - Male -MH - Postprandial Period -EDAT- 2011/02/09 06:00 -MHDA- 2011/06/03 06:00 -CRDT- 2011/02/09 06:00 -PHST- 2011/02/09 06:00 [entrez] -PHST- 2011/02/09 06:00 [pubmed] -PHST- 2011/06/03 06:00 [medline] -AID - B4248 [pii] -PST - ppublish -SO - Dan Med Bull. 2011 Feb;58(2):B4248. - -PMID- 19821382 -OWN - NLM -STAT- MEDLINE -DCOM- 20100127 -LR - 20250623 -IS - 1469-493X (Electronic) -IS - 1361-6137 (Linking) -IP - 4 -DP - 2009 Oct 7 -TI - Chinese herbal medicines for people with impaired glucose tolerance or impaired - fasting blood glucose. -PG - CD006690 -LID - 10.1002/14651858.CD006690.pub2 [doi] -AB - BACKGROUND: Around 308 million people worldwide are estimated to have impaired - glucose tolerance (IGT); 25% to 75% of these will develop diabetes within a - decade of initial diagnosis. At diagnosis, half will have tissue-related damage - and all have an increased risk for coronary heart disease. OBJECTIVES: The - objective of this review was to assess the effects and safety of Chinese herbal - medicines for the treatment of people with impaired glucose tolerance or impaired - fasting glucose (IFG). SEARCH STRATEGY: We searched the following databases: The - Cochrane Library, PubMed, EMBASE, AMED, a range of Chinese language databases, - SIGLE and databases of ongoing trials. SELECTION CRITERIA: Randomised clinical - trials comparing Chinese herbal medicines with placebo, no treatment, - pharmacological or non-pharmacological interventions in people with IGT or IFG - were considered. DATA COLLECTION AND ANALYSIS: Two authors independently - extracted data. Trials were assessed for risk of bias against key criteria: - random sequence generation, allocation concealment, blinding of participants, - outcome assessors and intervention providers, incomplete outcome data, selective - outcome reporting and other sources of bias. MAIN RESULTS: This review examined - 16 trials lasting four weeks to two years involving 1391 participants receiving - 15 different Chinese herbal medicines in eight different comparisons. No trial - reported on mortality, morbidity or costs. No serious adverse events like severe - hypoglycaemia were observed. Meta-analysis of eight trials showed that those - receiving Chinese herbal medicines combined with lifestyle modification were more - than twice as likely to have their fasting plasma glucose levels return to normal - levels (i.e. fasting plasma glucose <7.8 mmol/L and 2hr blood glucose <11.1 - mmol/L) compared to lifestyle modification alone (RR 2.07; 95% confidence - intervall (CI) 1.52 to 2.82). Those receiving Chinese herbs were less likely to - progress to diabetes over the duration of the trial (RR 0.33; 95% CI 0.19 to - 0.58). However, all trials had a considerable risk of bias and none of the - specific herbal medicines comparison data was available from more than one study. - Moreover, results could have been confounded by rates of natural reversion to - normal glucose levels. AUTHORS' CONCLUSIONS: The positive evidence in favour of - Chinese herbal medicines for the treatment of IGT or IFG is constrained by the - following factors: lack of trials that tested the same herbal medicine, lack of - details on co-interventions, unclear methods of randomisation, poor reporting and - other risks of bias. -FAU - Grant, Suzanne J -AU - Grant SJ -AD - University of Western Sydney, Locked Bag 1797, Penrith, South DC, Australia, NWS - 1797. -FAU - Bensoussan, Alan -AU - Bensoussan A -FAU - Chang, Dennis -AU - Chang D -FAU - Kiat, Hosen -AU - Kiat H -FAU - Klupp, Nerida L -AU - Klupp NL -FAU - Liu, Jian Ping -AU - Liu JP -FAU - Li, Xun -AU - Li X -LA - eng -GR - R24 AT001293/AT/NCCIH NIH HHS/United States -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -DEP - 20091007 -PL - England -TA - Cochrane Database Syst Rev -JT - The Cochrane database of systematic reviews -JID - 100909747 -RN - 0 (Blood Glucose) -RN - 0 (Drugs, Chinese Herbal) -SB - IM -MH - *Blood Glucose -MH - Drugs, Chinese Herbal/adverse effects/*therapeutic use -MH - Fasting/*blood -MH - Glucose Intolerance/blood/*drug therapy -MH - Humans -MH - Life Style -MH - Randomized Controlled Trials as Topic -PMC - PMC3191296 -MID - NIHMS307131 -EDAT- 2009/10/13 06:00 -MHDA- 2010/01/28 06:00 -PMCR- 2011/10/12 -CRDT- 2009/10/13 06:00 -PHST- 2009/10/13 06:00 [entrez] -PHST- 2009/10/13 06:00 [pubmed] -PHST- 2010/01/28 06:00 [medline] -PHST- 2011/10/12 00:00 [pmc-release] -AID - 10.1002/14651858.CD006690.pub2 [doi] -PST - epublish -SO - Cochrane Database Syst Rev. 2009 Oct 7;(4):CD006690. doi: - 10.1002/14651858.CD006690.pub2. - -PMID- 20449698 -OWN - NLM -STAT- MEDLINE -DCOM- 20100826 -LR - 20151119 -IS - 1865-8652 (Electronic) -IS - 0741-238X (Linking) -VI - 27 -IP - 4 -DP - 2010 Apr -TI - Ranolazine (Ranexa) in the treatment of chronic stable angina. -PG - 193-201 -LID - 10.1007/s12325-010-0018-5 [doi] -AB - Ischemic heart disease is the major cause of morbidity and mortality in the - Western world. Patients often suffer a reduction in quality of life due to - chronic stable angina, but therapeutic options can be limited due to concerns for - heart rate and blood pressure, as well as side effect profiles. Even - revascularization therapy has its limitations and newer agents are required to - help in this battle for symptomatic relief. Ranolazine (Ranexa(R), A. Menarini - Pharma UK, High Wycombe, UK) is a drug with a novel mechanism of action that has - been shown in several large trials to be an efficacious adjunctive agent in - reducing symptoms of chronic stable angina. It is thought to work by inhibiting - the late sodium current in cardiac myocytes, thereby reducing sodium and calcium - overload that follows ischemia. This improves myocardial relaxation and reduces - left ventricular diastolic stiffness, which in turn enhances myocardial - contractility and perfusion. The drug is generally well tolerated and the - evidence so far is encouraging, with a clear clinical benefit achieved in the - target groups. Its main strength is that it does not appear to affect either - heart rate or blood pressure. This review provides an insight into this treatment - option, describes the clinical trials evidence, proposed mechanism of action, and - pharmacokinetics, and outlines the indications for its use in chronic stable - angina. -FAU - Aslam, Sajid -AU - Aslam S -AD - Division of Cardiovascular Medicine, University Hospital, Nottingham, UK. -FAU - Gray, David -AU - Gray D -LA - eng -PT - Journal Article -PT - Review -DEP - 20100507 -PL - United States -TA - Adv Ther -JT - Advances in therapy -JID - 8611864 -RN - 0 (Acetanilides) -RN - 0 (Cardiovascular Agents) -RN - 0 (Piperazines) -RN - A6IEZ5M406 (Ranolazine) -MH - Acetanilides/administration & dosage/pharmacokinetics/*therapeutic use -MH - Angina Pectoris/*drug therapy/surgery -MH - Cardiovascular Agents/administration & dosage/pharmacokinetics/*therapeutic use -MH - Chronic Disease -MH - Coronary Artery Bypass -MH - Drug Therapy, Combination -MH - Humans -MH - Piperazines/administration & dosage/pharmacokinetics/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Ranolazine -RF - 26 -EDAT- 2010/05/08 06:00 -MHDA- 2010/08/27 06:00 -CRDT- 2010/05/08 06:00 -PHST- 2010/01/30 00:00 [received] -PHST- 2010/05/08 06:00 [entrez] -PHST- 2010/05/08 06:00 [pubmed] -PHST- 2010/08/27 06:00 [medline] -AID - 10.1007/s12325-010-0018-5 [doi] -PST - ppublish -SO - Adv Ther. 2010 Apr;27(4):193-201. doi: 10.1007/s12325-010-0018-5. Epub 2010 May - 7. - -PMID- 20520536 -OWN - NLM -STAT- MEDLINE -DCOM- 20101108 -LR - 20161125 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 25 -IP - 5 -DP - 2010 Sep -TI - Right ventricular imaging by two-dimensional and three-dimensional - echocardiography. -PG - 423-9 -LID - 10.1097/HCO.0b013e32833b55c4 [doi] -AB - PURPOSE OF REVIEW: The assessment of ventricular systolic performance is one of - the most critical roles of echocardiography, often impacting the diagnosis, - management, and prognosis of patients with suspected cardiovascular disease. - RECENT FINDINGS: Historically, the echocardiographic assessment of diseases - affecting the right ventricle has lagged behind that of the left ventricle, - despite knowledge demonstrating that diseases affecting the right heart have been - shown to have the same clinical consequences as those affecting the left heart. - SUMMARY: This up-to-date review of right ventricular imaging by two-dimensional - and three-dimensional echocardiography will emphasize the clinical situations for - which assessment of right ventricular systolic function is particularly - important, and review the systematic assessment of right ventricular regional - wall motion in terms of coronary anatomy. Technical and scanning tips designed to - optimize the visualization of the right heart with echocardiography with case - examples will be presented. Qualitative and quantitative two-dimensional methods - for assessing right heart function that are both well established and evolving - will be summarized and the case for considering more routine use of ultrasound - contrast agents to enhance right ventricular endocardial border definition will - be made. The current state of three-dimensional imaging of the right ventricle - will be highlighted along with the challenges for making this powerful tool more - widespread. -FAU - Mangion, Judy R -AU - Mangion JR -AD - Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard - Medical School, Boston, Massachusetts, USA. jmangion@partners.org -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -SB - IM -MH - *Echocardiography/methods -MH - *Echocardiography, Three-Dimensional/methods -MH - Heart Ventricles/*diagnostic imaging -MH - Humans -EDAT- 2010/06/04 06:00 -MHDA- 2010/11/09 06:00 -CRDT- 2010/06/04 06:00 -PHST- 2010/06/04 06:00 [entrez] -PHST- 2010/06/04 06:00 [pubmed] -PHST- 2010/11/09 06:00 [medline] -AID - 10.1097/HCO.0b013e32833b55c4 [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2010 Sep;25(5):423-9. doi: 10.1097/HCO.0b013e32833b55c4. - -PMID- 16781946 -OWN - NLM -STAT- MEDLINE -DCOM- 20061101 -LR - 20250529 -IS - 1050-1738 (Print) -IS - 1873-2615 (Electronic) -IS - 1050-1738 (Linking) -VI - 16 -IP - 5 -DP - 2006 Jul -TI - Cardioprotection by adiponectin. -PG - 141-6 -AB - Obesity-related disorders are closely associated with the pathogenesis of - cardiovascular disease. Adiponectin is a circulating adipose tissue-derived - hormone that is down-regulated in obese individuals. Hypoadiponectinemia has been - identified as an independent risk factor for type 2 diabetes, coronary artery - disease, and hypertension, and experimental studies show that adiponectin plays a - protective role in the development of insulin resistance, atherosclerosis, and - inflammation. More recent findings have shown that adiponectin directly affects - signaling in myocardial cells and exerts beneficial actions on the heart after - pressure overload and ischemia-reperfusion injury. This review focuses on the - role of adiponectin in the regulation of myocardial remodeling and acute cardiac - injury. -FAU - Ouchi, Noriyuki -AU - Ouchi N -AD - Molecular Cardiology/Whitaker Cardiovascular Institute, Boston University School - of Medicine, 715 Albany Street, Boston, MA 02118, USA. -FAU - Shibata, Rei -AU - Shibata R -FAU - Walsh, Kenneth -AU - Walsh K -LA - eng -GR - AR 40197/AR/NIAMS NIH HHS/United States -GR - R01 AG015052/AG/NIA NIH HHS/United States -GR - R37 AG015052/AG/NIA NIH HHS/United States -GR - P01 HL081587/HL/NHLBI NIH HHS/United States -GR - HL 81587/HL/NHLBI NIH HHS/United States -GR - AG 15052/AG/NIA NIH HHS/United States -GR - HL 77774/HL/NHLBI NIH HHS/United States -GR - R01 AR040197/AR/NIAMS NIH HHS/United States -GR - R01 HL077774/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Trends Cardiovasc Med -JT - Trends in cardiovascular medicine -JID - 9108337 -RN - 0 (Adiponectin) -SB - IM -MH - Adiponectin/deficiency/*physiology -MH - Animals -MH - Cardiomyopathy, Hypertrophic/*etiology -MH - Heart Failure/etiology -MH - Humans -MH - Mice -MH - Myocardial Reperfusion Injury/*etiology -MH - Obesity/*complications -MH - Risk Factors -PMC - PMC2749293 -MID - NIHMS141138 -EDAT- 2006/06/20 09:00 -MHDA- 2006/11/02 09:00 -PMCR- 2009/09/23 -CRDT- 2006/06/20 09:00 -PHST- 2006/01/18 00:00 [received] -PHST- 2006/03/01 00:00 [revised] -PHST- 2006/03/02 00:00 [accepted] -PHST- 2006/06/20 09:00 [pubmed] -PHST- 2006/11/02 09:00 [medline] -PHST- 2006/06/20 09:00 [entrez] -PHST- 2009/09/23 00:00 [pmc-release] -AID - S1050-1738(06)00043-0 [pii] -AID - 10.1016/j.tcm.2006.03.001 [doi] -PST - ppublish -SO - Trends Cardiovasc Med. 2006 Jul;16(5):141-6. doi: 10.1016/j.tcm.2006.03.001. - -PMID- 18058731 -OWN - NLM -STAT- MEDLINE -DCOM- 20080117 -LR - 20170302 -IS - 0423-104X (Print) -IS - 0423-104X (Linking) -VI - 58 -IP - 4 -DP - 2007 Jul-Aug -TI - [Natriuretic peptides: their role in diagnosis and therapy]. -PG - 364-74 -AB - Cardiac natriuretic peptide hormones, atrial natriuretic peptide (ANP) and B-type - natriuretic peptide (BNP), are synthesized and secreted by the heart, producing - several biological effects, such as natriuresis, vasorelaxation and hypotension. - During the last decade these peptides, especially BNP, have received increasing - attention as potential markers of cardiovascular disease. Their measurements can - be used to diagnose heart failure, including diastolic dysfunction, and using - them has been shown to save money. BNP levels can enable the differentiation - between dyspnoic patients secondary to ventricular dysfunction and subjects with - primary respiratory disorders. Moreover, there is good evidence that natriuretic - peptides may have a diagnostic role in arterial hypertension, acute coronary - syndromes, pulmonary hypertension, some valvular heart disease and some disorders - affecting other systems (diabetes or thyroid disorders). In this paper we discuss - the clinical utility of assessment of natriuretic peptide hormones in the - diagnosis of various clinical conditions and their use as pharmacological agents. -FAU - Pakuła, Dorota -AU - Pakuła D -AD - II Oddział Chorób Wewnetrznych z Pododdziałem Endokrynologii i Diabetologii, - Wojewódzki Szpital Specjalistyczny nr 3, Rybnik. pakdor@interia.pl -FAU - Marek, Bogdan -AU - Marek B -FAU - Kajdaniuk, Dariusz -AU - Kajdaniuk D -FAU - Kos-Kudła, Beata -AU - Kos-Kudła B -FAU - Borgiel-Marek, Halina -AU - Borgiel-Marek H -FAU - Krysiak, Robert -AU - Krysiak R -FAU - Gatnar, Aleksander -AU - Gatnar A -FAU - Pakuła, Piotr -AU - Pakuła P -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Peptydy natriuretyczne: ich znaczenie w diagnostyce i terapii. -PL - Poland -TA - Endokrynol Pol -JT - Endokrynologia Polska -JID - 0370674 -RN - 0 (Biomarkers) -RN - 0 (Cardiovascular Agents) -RN - 0 (Natriuretic Peptides) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - 85637-73-6 (Atrial Natriuretic Factor) -SB - IM -MH - Atrial Natriuretic Factor/physiology/therapeutic use -MH - Biomarkers/analysis -MH - Cardiovascular Agents/therapeutic use -MH - Cardiovascular Diseases/*diagnosis/*drug therapy -MH - Humans -MH - Natriuretic Peptide, Brain/physiology/therapeutic use -MH - Natriuretic Peptides/*physiology/*therapeutic use -RF - 77 -EDAT- 2007/12/07 09:00 -MHDA- 2008/01/18 09:00 -CRDT- 2007/12/07 09:00 -PHST- 2007/12/07 09:00 [pubmed] -PHST- 2008/01/18 09:00 [medline] -PHST- 2007/12/07 09:00 [entrez] -PST - ppublish -SO - Endokrynol Pol. 2007 Jul-Aug;58(4):364-74. - -PMID- 23197156 -OWN - NLM -STAT- MEDLINE -DCOM- 20130603 -LR - 20220330 -IS - 1473-6543 (Electronic) -IS - 1062-4821 (Print) -IS - 1062-4821 (Linking) -VI - 22 -IP - 1 -DP - 2013 Jan -TI - Diagnostic tools for hypertension and salt sensitivity testing. -PG - 65-76 -LID - 10.1097/MNH.0b013e32835b3693 [doi] -AB - PURPOSE OF REVIEW: One-third of the world's population has hypertension and it is - responsible for almost 50% of deaths from stroke or coronary heart disease. These - statistics do not distinguish salt-sensitive from salt-resistant hypertension or - include normotensives who are salt-sensitive even though salt sensitivity, - independent of blood pressure, is a risk factor for cardiovascular and other - diseases, including cancer. This review describes new personalized diagnostic - tools for salt sensitivity. RECENT FINDINGS: The relationship between salt intake - and cardiovascular risk is not linear, but rather fits a J-shaped curve - relationship. Thus, a low-salt diet may not be beneficial to everyone and may - paradoxically increase blood pressure in some individuals. Current surrogate - markers of salt sensitivity are not adequately sensitive or specific. Tests in - the urine that could be surrogate markers of salt sensitivity with a quick - turn-around time include renal proximal tubule cells, exosomes, and microRNA shed - in the urine. SUMMARY: Accurate testing of salt sensitivity is not only laborious - but also expensive, and with low patient compliance. Patients who have normal - blood pressure but are salt-sensitive cannot be diagnosed in an office setting - and there are no laboratory tests for salt sensitivity. Urinary surrogate markers - for salt sensitivity are being developed. -FAU - Felder, Robin A -AU - Felder RA -AD - Department of Pathology, The University of Virginia, Health Sciences Center, - Charlottesville, Virginia, USA. -FAU - White, Marquitta J -AU - White MJ -FAU - Williams, Scott M -AU - Williams SM -FAU - Jose, Pedro A -AU - Jose PA -LA - eng -GR - R01 DK039308/DK/NIDDK NIH HHS/United States -GR - P01 HL068686/HL/NHLBI NIH HHS/United States -GR - R01 HL023081/HL/NHLBI NIH HHS/United States -GR - R01 DK090918/DK/NIDDK NIH HHS/United States -GR - HL023081/HL/NHLBI NIH HHS/United States -GR - HL068686/HL/NHLBI NIH HHS/United States -GR - HL092196/HL/NHLBI NIH HHS/United States -GR - R01 HL092196/HL/NHLBI NIH HHS/United States -GR - DK090918/DK/NIDDK NIH HHS/United States -GR - P01 HL074940/HL/NHLBI NIH HHS/United States -GR - HL074940/HL/NHLBI NIH HHS/United States -GR - T32 GM080178/GM/NIGMS NIH HHS/United States -GR - DK039308/DK/NIDDK NIH HHS/United States -GR - R37 HL023081/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - England -TA - Curr Opin Nephrol Hypertens -JT - Current opinion in nephrology and hypertension -JID - 9303753 -RN - 0 (Biomarkers) -RN - 0 (Sodium Chloride, Dietary) -RN - EC 2.7.11.16 (G-Protein-Coupled Receptor Kinase 4) -RN - EC 2.7.11.16 (GRK4 protein, human) -SB - IM -MH - Biomarkers -MH - Blood Pressure/*drug effects/genetics -MH - Exosomes -MH - G-Protein-Coupled Receptor Kinase 4/genetics -MH - *Genetic Testing -MH - Humans -MH - Hypertension/*diagnosis/*genetics -MH - Kidney Tubules, Proximal/cytology -MH - Sodium Chloride, Dietary/*adverse effects -PMC - PMC3724405 -MID - NIHMS490500 -COIS- Conflicts of interest Drs. Robin A. Felder and Pedro A. Jose are co-owners of - Hypogen Inc. and own the use patent for GRK4 (G protein-related kinase mutants in - essential hypertension, U.S. Patent Number 6,660,474); and a U.S. Provisional - Patent Application Serial No. 61,636,576 on Compositions and Methods for - Identifying and Diagnosing Salt Sensitivity of Blood Pressure. Dr Scott M. - Williams is a member of the External Advisory Board of Hypogen, Inc. and is - co-owner of U.S. Provisional Patent Application Serial No. 61,636,576. -EDAT- 2012/12/01 06:00 -MHDA- 2013/06/05 06:00 -PMCR- 2013/09/01 -CRDT- 2012/12/01 06:00 -PHST- 2012/12/01 06:00 [entrez] -PHST- 2012/12/01 06:00 [pubmed] -PHST- 2013/06/05 06:00 [medline] -PHST- 2013/09/01 00:00 [pmc-release] -AID - 10.1097/MNH.0b013e32835b3693 [doi] -PST - ppublish -SO - Curr Opin Nephrol Hypertens. 2013 Jan;22(1):65-76. doi: - 10.1097/MNH.0b013e32835b3693. - -PMID- 21196250 -OWN - NLM -STAT- MEDLINE -DCOM- 20110421 -LR - 20220225 -IS - 2768-6698 (Electronic) -IS - 2768-6698 (Linking) -VI - 16 -IP - 4 -DP - 2011 Jan 1 -TI - Brown adipose tissue growth and development: significance and nutritional - regulation. -PG - 1589-608 -AB - The last decade has witnessed a profound resurgence in brown adipose tissue (BAT) - research. The need for such a dramatic increase stems from the ever-growing trend - toward global obesity. Indeed, it is currently estimated that rates of obesity in - developed countries such as the United States exceed 35% of the population (1). - The higher incidence of obesity is associated with increased prevalence of the - metabolic syndrome including diabetes, hypertension, and coronary heart disease, - among others (1, 2). BAT holds great promise in combating obesity given its - unprecedented metabolic capacity. Leading the way has been recent studies, which - conclusively demonstrate significant quantities of functional BAT in adult humans - (3-7). These findings have been complimented by elegant studies elucidating the - developmental origin of the brown adipocyte and the transcriptional regulation - involved in its differentiation. This review will attempt to meld the wealth of - new information regarding BAT development with established literature to provide - an up to date synopsis of what is known and thus a framework for future research - directions. -FAU - Satterfield, Michael Carey -AU - Satterfield MC -AD - Department of Animal Science, Texas A and M University, College Station, TX - 77843-2471, USA. csatterfield@tamu.edu -FAU - Wu, Guoyao -AU - Wu G -LA - eng -GR - 1R21 HD049449/HD/NICHD NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110101 -PL - Singapore -TA - Front Biosci (Landmark Ed) -JT - Frontiers in bioscience (Landmark edition) -JID - 101612996 -RN - 0 (Bone Morphogenetic Proteins) -RN - 0 (Catecholamines) -RN - 0 (DNA-Binding Proteins) -RN - 0 (Heat-Shock Proteins) -RN - 0 (Ion Channels) -RN - 0 (Mitochondrial Proteins) -RN - 0 (PPARGC1A protein, human) -RN - 0 (PRDM16 protein, human) -RN - 0 (Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha) -RN - 0 (Receptors, Adrenergic, beta) -RN - 0 (Thyroid Hormones) -RN - 0 (Transcription Factors) -RN - 0 (Uncoupling Protein 1) -RN - 94ZLA3W45F (Arginine) -SB - IM -MH - Adipocytes, Brown/cytology/drug effects/physiology -MH - Adipose Tissue, Brown/drug effects/growth & development/*physiology -MH - Adult -MH - Aged -MH - Animals -MH - Animals, Newborn -MH - Arginine/administration & dosage -MH - Body Temperature Regulation/drug effects/*physiology -MH - Bone Morphogenetic Proteins/physiology -MH - Catecholamines/physiology -MH - Cell Differentiation/drug effects -MH - Cell Lineage -MH - DNA-Binding Proteins/physiology -MH - Diet/adverse effects -MH - Dietary Supplements -MH - Gene Expression Regulation -MH - Heat-Shock Proteins/physiology -MH - Humans -MH - Infant, Newborn -MH - Ion Channels/physiology -MH - Lipolysis/drug effects -MH - Middle Aged -MH - Mitochondrial Proteins/physiology -MH - Obesity/etiology -MH - Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha -MH - Receptors, Adrenergic, beta/physiology -MH - Sheep -MH - Thyroid Hormones/physiology -MH - Transcription Factors/physiology -MH - Uncoupling Protein 1 -EDAT- 2011/01/05 06:00 -MHDA- 2011/04/22 06:00 -CRDT- 2011/01/04 06:00 -PHST- 2011/01/04 06:00 [entrez] -PHST- 2011/01/05 06:00 [pubmed] -PHST- 2011/04/22 06:00 [medline] -AID - 3807 [pii] -AID - 10.2741/3807 [doi] -PST - epublish -SO - Front Biosci (Landmark Ed). 2011 Jan 1;16(4):1589-608. doi: 10.2741/3807. - -PMID- 24286592 -OWN - NLM -STAT- MEDLINE -DCOM- 20140821 -LR - 20220410 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Print) -IS - 0167-5273 (Linking) -VI - 170 -IP - 3 -DP - 2014 Jan 1 -TI - Substance P in heart failure: the good and the bad. -PG - 270-7 -LID - S0167-5273(13)01982-7 [pii] -LID - 10.1016/j.ijcard.2013.11.010 [doi] -AB - The tachykinin, substance P, is found primarily in sensory nerves. In the heart, - substance P-containing nerve fibers are often found surrounding coronary vessels, - making them ideally situated to sense changes in the myocardial environment. - Recent studies in rodents have identified substance P as having dual roles in the - heart, depending on disease etiology and/or timing. Thus far, these studies - indicate that substance P may be protective acutely following - ischemia-reperfusion, but damaging long-term in non-ischemic induced remodeling - and heart failure. Sensory nerves may be at the apex of the cascade of events - leading to heart failure, therefore, they make a promising potential therapeutic - target that warrants increased investigation. -CI - Copyright © 2013. Published by Elsevier Ireland Ltd. -FAU - Dehlin, Heather M -AU - Dehlin HM -AD - Department of Pharmacology and Toxicology, Medical College of Wisconsin, - Milwaukee, WI 53226, United States; Cardiovascular Research Center, Medical - College of Wisconsin, Milwaukee, WI 53226, United States. -FAU - Levick, Scott P -AU - Levick SP -AD - Department of Pharmacology and Toxicology, Medical College of Wisconsin, - Milwaukee, WI 53226, United States; Cardiovascular Research Center, Medical - College of Wisconsin, Milwaukee, WI 53226, United States. Electronic address: - slevick@mcw.edu. -LA - eng -GR - R00 HL093215/HL/NHLBI NIH HHS/United States -GR - T32 HL007792/HL/NHLBI NIH HHS/United States -GR - R00-HL-093215/HL/NHLBI NIH HHS/United States -GR - T32-HL007792/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20131112 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 33507-63-0 (Substance P) -SB - IM -CIN - Int J Cardiol. 2016 Mar 1;206:167-8. doi: 10.1016/j.ijcard.2015.10.196. PMID: - 26541698 -MH - Animals -MH - Heart/innervation/*physiology -MH - Heart Failure/*physiopathology -MH - Humans -MH - Sensory Receptor Cells/physiology -MH - Substance P/*physiology -MH - Ventricular Remodeling/*physiology -PMC - PMC4450674 -MID - NIHMS684171 -OTO - NOTNLM -OT - Heart failure -OT - Myocardial remodeling -OT - Neuropeptide -OT - Sensory nerve -OT - Substance P -OT - Tachykinin -EDAT- 2013/11/30 06:00 -MHDA- 2014/08/22 06:00 -PMCR- 2015/06/01 -CRDT- 2013/11/30 06:00 -PHST- 2013/01/29 00:00 [received] -PHST- 2013/06/12 00:00 [revised] -PHST- 2013/11/02 00:00 [accepted] -PHST- 2013/11/30 06:00 [entrez] -PHST- 2013/11/30 06:00 [pubmed] -PHST- 2014/08/22 06:00 [medline] -PHST- 2015/06/01 00:00 [pmc-release] -AID - S0167-5273(13)01982-7 [pii] -AID - 10.1016/j.ijcard.2013.11.010 [doi] -PST - ppublish -SO - Int J Cardiol. 2014 Jan 1;170(3):270-7. doi: 10.1016/j.ijcard.2013.11.010. Epub - 2013 Nov 12. - -PMID- 24129298 -OWN - NLM -STAT- MEDLINE -DCOM- 20140114 -LR - 20131016 -IS - 1661-8157 (Print) -IS - 1661-8157 (Linking) -VI - 102 -IP - 21 -DP - 2013 Oct 16 -TI - [Heart failure with preserved left ventricular ejection fraction]. -PG - 1299-307 -LID - 10.1024/1661-8157/a001439 [doi] -AB - Heart failure with preserved left ventricular ejection fraction (LVEF; HFpEF) is - a common type of heart failure in the elderly, and it typically represents - advanced hypertensive heart disease. The left ventricle in patients with HFpEF is - characterized by concentric remodeling, normal LVEF, but reduced left - longitudinal shortening, and importantly diastolic dysfunction. Dyspnoe and - fatigue in patients with HFpEF are due to impaired left ventricular filling with - a rapid increase in filling pressures and the lack of an increase in stroke - volume during exercise. The diagnosis of HFpEF requires the careful exclusion of - non-cardiac causes of dyspnoe as well as cardiac causes of dyspnoe associated - with preserved LVEF other than HFpEF, primarily coronary artery disease and valve - disease. Then, the following findings are required to make a diagnosis of HFpEF: - a non-dilated left ventricle with an LVEF >50% and the presence of a significant - diastolic impairment, which can be assessed using invasive haemodynamics, - echocardiography, natriuretic peptides, or a combination of these tools. In - contrast to patients with heart failure and reduced LVEF there is still no - established treatment for patients with HFpEF, which prolongs survival or reduces - the rate of hospitalizations for heart failure. There is currently however - intense research going on in this field, and results from large trials evaluating - the effects of various interventions on clinical endpoints are expected within - the next years. -FAU - Maeder, Micha T -AU - Maeder MT -AD - Fachbereich Kardiologie, Kantonsspital St. Gallen. -FAU - Rickli, Hans -AU - Rickli H -LA - ger -PT - Comparative Study -PT - English Abstract -PT - Journal Article -PT - Review -TT - Herzinsuffizienz mit erhaltener linksventrikulärer Auswurffraktion. -PL - Switzerland -TA - Praxis (Bern 1994) -JT - Praxis -JID - 101468093 -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Antihypertensive Agents/therapeutic use -MH - Echocardiography/drug effects -MH - Heart Failure/diagnosis/drug therapy/etiology/*physiopathology -MH - Humans -MH - Hypertension/diagnosis/drug therapy/etiology/physiopathology -MH - Risk Factors -MH - Stroke Volume/drug effects/*physiology -MH - Ventricular Dysfunction, Left/diagnosis/drug therapy/etiology/*physiopathology -OTO - NOTNLM -OT - Auswurffraktion -OT - Herzinsuffizienz -OT - diastolic -OT - diastolisch -OT - dysfonction diastolique -OT - ejection fraction -OT - erhalten -OT - fonction systolique préservée -OT - fraction d'éjection -OT - heart failure -OT - insuffisance cardiaque -OT - normal -OT - preserved -EDAT- 2013/10/17 06:00 -MHDA- 2014/01/15 06:00 -CRDT- 2013/10/17 06:00 -PHST- 2013/10/17 06:00 [entrez] -PHST- 2013/10/17 06:00 [pubmed] -PHST- 2014/01/15 06:00 [medline] -AID - 6204282786757642 [pii] -AID - 10.1024/1661-8157/a001439 [doi] -PST - ppublish -SO - Praxis (Bern 1994). 2013 Oct 16;102(21):1299-307. doi: 10.1024/1661-8157/a001439. - -PMID- 24377458 -OWN - NLM -STAT- MEDLINE -DCOM- 20140929 -LR - 20181203 -IS - 1744-7607 (Electronic) -IS - 1742-5255 (Linking) -VI - 10 -IP - 2 -DP - 2014 Feb -TI - An evaluation of the pharmacokinetics and pharmacodynamics of ivabradine for the - treatment of heart failure. -PG - 279-91 -LID - 10.1517/17425255.2014.876005 [doi] -AB - INTRODUCTION: Ivabradine is a new heart-rate-lowering drug; the aim of this - review was to analyze its role in heart failure (HF). AREAS COVERED: This - systematic review on the role of ivabradine in HF is based on material searched - and obtained through Pubmed and Medline up to September 2013. EXPERT OPINION: - Heart rate (HR) is a risk factor in patients with HF, and its reduction is - considered an important goal of therapy. The BEAUTIFUL trial demonstrated the - benefits of ivabradine on prognosis (only on ischemic endpoints) in patients with - coronary artery disease (CAD) and left ventricular systolic dysfunction (LVSD) - and HR ≥ 60 bpm. In the SHIFT trial, which enrolled patients with LVSD, HF and HR - ≥ 70 bpm, ivabradine administration (on top of guideline-based therapy, including - β-blockers [BB]) was associated with a reduction of cardiovascular death and - hospitalizations for HF, but BB were underutilized. Further studies are needed to - test the efficacy of ivabradine in CAD patients with high HR and to shed light on - the comparison between ivabradine and a more aggressive therapy with higher doses - of BB in HF patients. -FAU - Rosa, Gian Marco -AU - Rosa GM -AD - University of Genoa, San Martino Hospital and National Institute for Cancer - Research, Department of Cardiology , Genoa , Italy. -FAU - Ferrero, Simone -AU - Ferrero S -FAU - Ghione, Paola -AU - Ghione P -FAU - Valbusa, Alberto -AU - Valbusa A -FAU - Brunelli, Claudio -AU - Brunelli C -LA - eng -PT - Journal Article -PT - Review -PT - Systematic Review -DEP - 20131231 -PL - England -TA - Expert Opin Drug Metab Toxicol -JT - Expert opinion on drug metabolism & toxicology -JID - 101228422 -RN - 0 (Benzazepines) -RN - 3H48L0LPZQ (Ivabradine) -SB - IM -MH - Animals -MH - Benzazepines/*pharmacokinetics/pharmacology/*therapeutic use -MH - Clinical Trials as Topic/methods -MH - Heart Failure/*drug therapy/*metabolism -MH - Heart Rate/*drug effects/physiology -MH - Humans -MH - Ivabradine -MH - Treatment Outcome -EDAT- 2014/01/01 06:00 -MHDA- 2014/09/30 06:00 -CRDT- 2014/01/01 06:00 -PHST- 2014/01/01 06:00 [entrez] -PHST- 2014/01/01 06:00 [pubmed] -PHST- 2014/09/30 06:00 [medline] -AID - 10.1517/17425255.2014.876005 [doi] -PST - ppublish -SO - Expert Opin Drug Metab Toxicol. 2014 Feb;10(2):279-91. doi: - 10.1517/17425255.2014.876005. Epub 2013 Dec 31. - -PMID- 21929617 -OWN - NLM -STAT- MEDLINE -DCOM- 20120228 -LR - 20230124 -IS - 1600-6143 (Electronic) -IS - 1600-6135 (Linking) -VI - 11 -IP - 11 -DP - 2011 Nov -TI - Bone marrow-derived cell transplantation therapy for myocardial infarction: - lessons learned and future questions. -PG - 2297-301 -LID - 10.1111/j.1600-6143.2011.03750.x [doi] -AB - Over the last decade, many investigators have utilized bone marrow-derived cells - for cell transplantation therapy in animal studies and in patients with acute - myocardial infarction and chronic heart failure. In those experimental and - clinical studies, various doses and types of bone marrow-derived cells have been - transplanted to the injured myocardium using a variety of approaches, such as - intracoronary infusion or catheter-based direct endomyocardial injection, and at - different time points after successful coronary reperfusion. The reported - treatment effects are variable, which may be related to differences in cell type - and quantity of transplanted cells, timing and approach of cell transplantation - and patient selection. In this review, we summarize and discuss the controversies - and questions related to the clinical use of bone marrow-derived cells. -CI - ©2011 The Authors Journal compilation © 2011 The American Society of - Transplantation and the American Society of Transplant Surgeons. -FAU - Dai, W -AU - Dai W -AD - The Heart Institute of Good Samaritan Hospital, Los Angeles, CA, USA. - Wangdedai@yahoo.com -FAU - Kloner, R A -AU - Kloner RA -LA - eng -PT - Journal Article -PT - Review -DEP - 20110919 -PL - United States -TA - Am J Transplant -JT - American journal of transplantation : official journal of the American Society of - Transplantation and the American Society of Transplant Surgeons -JID - 100968638 -SB - IM -MH - Animals -MH - *Bone Marrow Transplantation/methods -MH - Cardiomyopathies/surgery -MH - Cell Transdifferentiation -MH - Chronic Disease -MH - Clinical Trials as Topic -MH - Hematopoietic Stem Cell Mobilization -MH - Humans -MH - Myocardial Infarction/*surgery -MH - Myocardium/cytology -MH - Time Factors -MH - Ventricular Dysfunction, Left -EDAT- 2011/09/21 06:00 -MHDA- 2012/03/01 06:00 -CRDT- 2011/09/21 06:00 -PHST- 2011/09/21 06:00 [entrez] -PHST- 2011/09/21 06:00 [pubmed] -PHST- 2012/03/01 06:00 [medline] -AID - S1600-6135(22)28145-3 [pii] -AID - 10.1111/j.1600-6143.2011.03750.x [doi] -PST - ppublish -SO - Am J Transplant. 2011 Nov;11(11):2297-301. doi: 10.1111/j.1600-6143.2011.03750.x. - Epub 2011 Sep 19. - -PMID- 16927934 -OWN - NLM -STAT- MEDLINE -DCOM- 20060927 -LR - 20191110 -IS - 1932-2275 (Print) -IS - 1932-2275 (Linking) -VI - 24 -IP - 2 -DP - 2006 Jun -TI - Pharmacologic modulation of operative risk in patients who have cardiac disease. -PG - 365-79 -AB - Cardiac complications continue to compose a major proportion of serious - postoperative morbidity and mortality, and it is appropriate, therefore, that - this area has received a lot of attention in the search for pharmacologic - modulation of surgical outcomes. Despite numerous studies, conclusive data does - not exist, making it difficult to recommend a course of action. beta-blockade has - not only made it into national protocols, but is even considered as a quality - assessment measure. However, the data are not quite as conclusive as it may - sometimes appear. There have been few studies, with a small number of negative - outcomes, and, at times, significant methodological concerns. The positive - outcomes of meta-analyses rest essentially on a single trial in a highly selected - patient population. Although use of beta-blockers in patients who have documented - coronary artery disease and are undergoing major vascular procedures appears - supported, it is premature to recommend beta-blockade for all patients with - cardiac risk. Because these drugs are not without risks, it might be advisable to - be restrained in their use until the results of the large-scale randomized POISE - trial are available. For clonidine and statins, the data are even more tenuous, - and largely based on retrospective reviews (with the exception of postprocedure - use of statins, which is well supported). Here again, the results of large-scale - prospective trials must become available before recommendations can be made. - Finally, promising data indicate that it might be possible to modulate by - pharmacologic means the neurocognitive decline that is frequently associated with - cardiac surgery, and which is often considered by patients to be the most - troublesome complication of the intervention. -FAU - Shilling, Ashley M -AU - Shilling AM -AD - Department of Anesthesia, University of Virginia Health System, Old Medical - School, Room 4748, Charlottesville, VA 22908-0710, USA. abm5f@virginia.edu -FAU - Durieux, Marcel E -AU - Durieux ME -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Anesthesiol Clin -JT - Anesthesiology clinics -JID - 101273663 -SB - IM -MH - *Cardiac Surgical Procedures/mortality -MH - Cognition Disorders/etiology/prevention & control -MH - Heart Diseases/*drug therapy/mortality/surgery -MH - Humans -MH - Intraoperative Complications/mortality/prevention & control -MH - Myocardial Ischemia/mortality/prevention & control -MH - Perioperative Care/methods -MH - Postoperative Complications/mortality/*prevention & control -MH - Risk Factors -MH - *Surgical Procedures, Operative/mortality -RF - 44 -EDAT- 2006/08/25 09:00 -MHDA- 2006/09/28 09:00 -CRDT- 2006/08/25 09:00 -PHST- 2006/08/25 09:00 [pubmed] -PHST- 2006/09/28 09:00 [medline] -PHST- 2006/08/25 09:00 [entrez] -AID - 10.1016/j.atc.2006.02.001 [doi] -PST - ppublish -SO - Anesthesiol Clin. 2006 Jun;24(2):365-79. doi: 10.1016/j.atc.2006.02.001. - -PMID- 19483048 -OWN - NLM -STAT- MEDLINE -DCOM- 20090917 -LR - 20130523 -IS - 1399-3003 (Electronic) -IS - 0903-1936 (Linking) -VI - 33 -IP - 6 -DP - 2009 Jun -TI - Cardiac magnetic resonance imaging for the assessment of the heart and pulmonary - circulation in pulmonary hypertension. -PG - 1454-66 -LID - 10.1183/09031936.00139907 [doi] -AB - Pulmonary hypertension is a disease of the pulmonary arteries resulting in a - progressive increase in pulmonary vascular resistance, ultimately leading to - right ventricular failure and death. The functional capacity of the right - ventricle is a major prognostic determinant. Our understanding of right ventricle - performance in pulmonary hypertension has been hindered by the lack of techniques - that give a reliable picture of right ventricle morphology and function. Cardiac - magnetic resonance (CMR) imaging enables a unique combination of morphological - and functional assessment of the right ventricle and pulmonary circulation. In - this review article, we introduce the technique of CMR imaging, review its use in - imaging of the heart and pulmonary circulation and discuss its current and future - application to the management of patients with pulmonary hypertension. There have - been recent major advances in our understanding of the mechanism of disease - development, in the diagnostic process, and in the treatment of pulmonary - hypertension. Therapeutic advances in the management have reinforced the - requirement for noninvasive, accurate and reproducible methods of assessment to - act as "end-points" to measure the effects of treatment. We anticipate CMR - imaging will increasingly be utilised as the primary modality for combined - anatomic and functional assessments that enable more complete and efficient - evaluation of pulmonary hypertension patients. -FAU - McLure, L E R -AU - McLure LE -AD - Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Clydebank, - West Dumbartonshire, Scotland, UK. -FAU - Peacock, A J -AU - Peacock AJ -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Eur Respir J -JT - The European respiratory journal -JID - 8803460 -RN - 0 (Contrast Media) -SB - IM -MH - Blood Flow Velocity -MH - Cardiac Catheterization -MH - Contrast Media -MH - Coronary Circulation -MH - Heart Ventricles/anatomy & histology/physiopathology -MH - Humans -MH - Hypertension, Pulmonary/*diagnosis/*physiopathology/therapy -MH - Hypertrophy, Right Ventricular/*diagnosis/*physiopathology -MH - Magnetic Resonance Imaging/*methods -MH - Pulmonary Circulation -RF - 81 -EDAT- 2009/06/02 09:00 -MHDA- 2009/09/18 06:00 -CRDT- 2009/06/02 09:00 -PHST- 2009/06/02 09:00 [entrez] -PHST- 2009/06/02 09:00 [pubmed] -PHST- 2009/09/18 06:00 [medline] -AID - 33/6/1454 [pii] -AID - 10.1183/09031936.00139907 [doi] -PST - ppublish -SO - Eur Respir J. 2009 Jun;33(6):1454-66. doi: 10.1183/09031936.00139907. - -PMID- 22939801 -OWN - NLM -STAT- MEDLINE -DCOM- 20130117 -LR - 20220317 -IS - 1879-0828 (Electronic) -IS - 0953-6205 (Linking) -VI - 23 -IP - 7 -DP - 2012 Oct -TI - Obstructive sleep apnea syndrome. -PG - 586-93 -LID - 10.1016/j.ejim.2012.05.013 [doi] -AB - Obstructive sleep apnea (OSA) syndrome is a common but often unrecognized - disorder caused by pharyngeal collapse during sleep and characterized by frequent - awakenings, disrupted sleep and consequent excessive daytime sleepiness. With the - increasing epidemic of obesity, the most important risk factor for OSA, - prevalence of the disease will increase over the coming years thus representing - an important public-health problem. In fact, it is now recognized that there is - an association between OSA and hypertension, metabolic syndrome, diabetes, heart - failure, coronary artery disease, arrhythmias, stroke, pulmonary hypertension, - neurocognitive and mood disorders. Diagnosis is based on the combined evaluation - of clinical manifestations and objective sleep study findings. Cardinal symptoms - include snoring, sleepiness and significant reports of sleep apnea episodes. - Polysomnography represents the gold standard to confirm the clinical suspicion of - OSA syndrome, to assess its severity and to guide therapeutic choices. - Behavioral, medical and surgical options are available for the treatment. - Continuous positive airway pressure (CPAP) represents the treatment of choice in - most patients. CPAP has been demonstrated to be effective in reducing symptoms, - cardiovascular morbidity and mortality and neurocognitive sequelae, but it is - often poorly tolerated. The results of clinical studies do not support surgery - and pharmacological therapy as first-line treatment, but these approaches might - be useful in selected patients. A better understanding of mechanisms underlying - the disease could improve therapeutic strategies and reduce the social impact of - OSA syndrome. -CI - Copyright © 2012 European Federation of Internal Medicine. Published by Elsevier - B.V. All rights reserved. -FAU - Mannarino, Massimo R -AU - Mannarino MR -AD - Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of - Clinical and Experimental Medicine, University of Perugia, Perugia, Italy. - massimo.mannarino@unipg.it -FAU - Di Filippo, Francesco -AU - Di Filippo F -FAU - Pirro, Matteo -AU - Pirro M -LA - eng -PT - Journal Article -PT - Review -DEP - 20120624 -PL - Netherlands -TA - Eur J Intern Med -JT - European journal of internal medicine -JID - 9003220 -SB - IM -CIN - Eur J Intern Med. 2013 Mar;24(2):e23. doi: 10.1016/j.ejim.2012.09.009. PMID: - 23040262 -CIN - Eur J Intern Med. 2013 Dec;24(8):e94-5. doi: 10.1016/j.ejim.2013.10.008. PMID: - 24268838 -MH - Arrhythmias, Cardiac/complications -MH - Cardiovascular Diseases/*complications -MH - Cognition Disorders/complications -MH - Continuous Positive Airway Pressure -MH - Heart Failure/complications -MH - Humans -MH - Hypertension/complications -MH - Obesity/complications -MH - Polysomnography -MH - Risk Factors -MH - *Sleep Apnea, Obstructive/complications/diagnosis/therapy -MH - Stroke/complications -EDAT- 2012/09/04 06:00 -MHDA- 2013/01/18 06:00 -CRDT- 2012/09/04 06:00 -PHST- 2012/03/06 00:00 [received] -PHST- 2012/05/08 00:00 [revised] -PHST- 2012/05/11 00:00 [accepted] -PHST- 2012/09/04 06:00 [entrez] -PHST- 2012/09/04 06:00 [pubmed] -PHST- 2013/01/18 06:00 [medline] -AID - S0953-6205(12)00152-5 [pii] -AID - 10.1016/j.ejim.2012.05.013 [doi] -PST - ppublish -SO - Eur J Intern Med. 2012 Oct;23(7):586-93. doi: 10.1016/j.ejim.2012.05.013. Epub - 2012 Jun 24. - -PMID- 21802578 -OWN - NLM -STAT- MEDLINE -DCOM- 20110922 -LR - 20240109 -IS - 1879-1913 (Electronic) -IS - 0002-9149 (Linking) -VI - 108 -IP - 3 Suppl -DP - 2011 Aug 2 -TI - Macrovascular effects and safety issues of therapies for type 2 diabetes. -PG - 25B-32B -LID - 10.1016/j.amjcard.2011.03.014 [doi] -AB - Type 2 diabetes has long been recognized as an independent risk factor for - cardiovascular disease (CVD), including coronary artery disease (CAD), stroke, - peripheral arterial disease, cardiomyopathy, and congestive heart failure. - Cardiovascular (CV) complications are the leading cause of comorbidity and death - in the patient with diabetes. Vascular complications of diabetes also extend to - microvascular disease, manifest as diabetic nephropathy, neuropathy, and - retinopathy. The impact of glycemic control in reducing microvascular - complications is well established. Although more controversial, there is also - evidence that glycemic control can limit macrovascular disease, including CAD, - peripheral arterial disease, and stroke. Glycemic control in the context of type - 2 diabetes, as well as prediabetes, is also intertwined with CV risk factors such - as obesity, hypertriglyceridemia, and blood pressure control. Similarly, major - issues and concerns have arisen around the CV safety of antidiabetic therapy. - Together, these issues have focused attention on the need to understand the CV - effects of current treatments for type 2 diabetes and the optimal strategies for - care of patients with this disease. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Plutzky, Jorge -AU - Plutzky J -AD - Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, - Boston, Massachusetts 02115, USA. jplutzky@rics.bwh.harvard.edu -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -RN - 0 (Glycated Hemoglobin A) -RN - 0 (Hypoglycemic Agents) -RN - 0 (Thiazolidinediones) -RN - X4OV71U42S (Pioglitazone) -SB - IM -MH - Atherosclerosis/epidemiology -MH - Diabetes Mellitus, Type 2/*drug therapy -MH - Diabetic Angiopathies/chemically induced/epidemiology/*physiopathology -MH - Diabetic Retinopathy/physiopathology -MH - Disease Progression -MH - Glycated Hemoglobin -MH - Humans -MH - Hyperglycemia/epidemiology -MH - Hypertriglyceridemia/epidemiology -MH - Hypoglycemic Agents/adverse effects/therapeutic use -MH - Obesity/epidemiology -MH - Pioglitazone -MH - Risk Factors -MH - Thiazolidinediones/therapeutic use -EDAT- 2011/08/10 06:00 -MHDA- 2011/09/23 06:00 -CRDT- 2011/08/02 06:00 -PHST- 2011/08/02 06:00 [entrez] -PHST- 2011/08/10 06:00 [pubmed] -PHST- 2011/09/23 06:00 [medline] -AID - S0002-9149(11)01215-X [pii] -AID - 10.1016/j.amjcard.2011.03.014 [doi] -PST - ppublish -SO - Am J Cardiol. 2011 Aug 2;108(3 Suppl):25B-32B. doi: - 10.1016/j.amjcard.2011.03.014. - -PMID- 22733213 -OWN - NLM -STAT- MEDLINE -DCOM- 20130124 -LR - 20220409 -IS - 1759-5010 (Electronic) -IS - 1759-5002 (Linking) -VI - 9 -IP - 9 -DP - 2012 Sep -TI - Heartache and heartbreak--the link between depression and cardiovascular disease. -PG - 526-39 -LID - 10.1038/nrcardio.2012.91 [doi] -AB - The close, bidirectional relationship between depression and cardiovascular - disease is well established. Major depression is associated with an increased - risk of coronary artery disease and acute cardiovascular sequelae, such as - myocardial infarction, congestive heart failure, and isolated systolic - hypertension. Morbidity and mortality in patients with cardiovascular disease and - depression are significantly higher than in patients with cardiovascular disease - who are not depressed. Various pathophysiological mechanisms might underlie the - risk of cardiovascular disease in patients with depression: increased - inflammation; increased susceptibility to blood clotting (owing to alterations in - multiple steps of the clotting cascade, including platelet activation and - aggregation); oxidative stress; subclinical hypothyroidism; hyperactivity of the - sympatho-adrenomedullary system and the hypothalamic-pituitary-adrenal axis; - reductions in numbers of circulating endothelial progenitor cells and associated - arterial repair processes; decreased heart rate variability; and the presence of - genetic factors. Early identification of patients with depression who are at risk - of cardiovascular disease, as well as prevention and appropriate treatment of - cardiovascular disease in these patients, is an important and attainable goal. - However, adequately powered studies are required to determine the optimal - treatment regimen for patients with both depression and cardiovascular disorders. -FAU - Nemeroff, Charles B -AU - Nemeroff CB -AD - Department of Psychiatry and Behavioral Sciences, University of Miami Leonard M. - Miller School of Medicine, 1120 NW 14th Street, Room 1455, Miami, FL 33136, USA. - cnemeroff@ med.miami.edu -FAU - Goldschmidt-Clermont, Pascal J -AU - Goldschmidt-Clermont PJ -LA - eng -GR - DA‑031201/DA/NIDA NIH HHS/United States -GR - MH‑078775/MH/NIMH NIH HHS/United States -GR - MH‑094759/MH/NIMH NIH HHS/United States -GR - R01CA136387/CA/NCI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20120626 -PL - England -TA - Nat Rev Cardiol -JT - Nature reviews. Cardiology -JID - 101500075 -SB - IM -MH - Acute Disease -MH - Cardiovascular Diseases/epidemiology/etiology/*psychology -MH - Depression/complications/epidemiology/*psychology -MH - Endothelium, Vascular -MH - Epigenomics -MH - Humans -MH - Inflammation -MH - Life Style -MH - Oxidative Stress -MH - Risk Factors -MH - Stress, Psychological -MH - United States/epidemiology -EDAT- 2012/06/27 06:00 -MHDA- 2013/01/25 06:00 -CRDT- 2012/06/27 06:00 -PHST- 2012/06/27 06:00 [entrez] -PHST- 2012/06/27 06:00 [pubmed] -PHST- 2013/01/25 06:00 [medline] -AID - nrcardio.2012.91 [pii] -AID - 10.1038/nrcardio.2012.91 [doi] -PST - ppublish -SO - Nat Rev Cardiol. 2012 Sep;9(9):526-39. doi: 10.1038/nrcardio.2012.91. Epub 2012 - Jun 26. - -PMID- 23732141 -OWN - NLM -STAT- MEDLINE -DCOM- 20140219 -LR - 20220321 -IS - 1969-6213 (Electronic) -IS - 1774-024X (Linking) -VI - 9 Suppl R -DP - 2013 May -TI - Potential role of renal sympathetic denervation for the treatment of cardiac - arrhythmias. -PG - R110-6 -LID - EIJV9SRA19 [pii] -LID - 10.4244/EIJV9SRA19 [doi] -AB - The autonomic nervous system (ANS) has a pivotal role in the pathogenesis and - maintenance of atrial and ventricular arrhythmias. Catheter-based renal - denervation (RDN) is associated with a reduction of central sympathetic activity, - muscle sympathetic nerve activity, and blood pressure in resistant hypertension. - As renal afferent nerves are regulators of central sympathetic tone, RDN opens - the possibility to modulate sympathetic activity, but without affecting - peripheral chemoreceptors and mechanoreceptors in the heart and other organs. RDN - was shown to reduce heart rate in humans and to reduce inducibility of atrial - fibrillation (AF) as well as ventricular rate during AF in experimental studies. - First evidence indicates that pulmonary vein isolation in combination with RDN - increases the rate of AF freedom in patients with resistant hypertension. - Furthermore, RDN may have a beneficial impact on ventricular arrhythmia, in - particular in patients with coronary artery disease or heart failure. -FAU - Ukena, Christian -AU - Ukena C -AD - Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische - Intensivmedizin), Universitätsklinikum des Saarlandes, Homburg/Saar, Germany. - Christian.Ukena@uks.eu -FAU - Mahfoud, Felix -AU - Mahfoud F -FAU - Linz, Dominik -AU - Linz D -FAU - Böhm, Michael -AU - Böhm M -FAU - Neuberger, Hans-Ruprecht -AU - Neuberger HR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - France -TA - EuroIntervention -JT - EuroIntervention : journal of EuroPCR in collaboration with the Working Group on - Interventional Cardiology of the European Society of Cardiology -JID - 101251040 -SB - IM -MH - Animals -MH - Arrhythmias, Cardiac/diagnosis/physiopathology/*surgery -MH - *Catheter Ablation -MH - Heart/*innervation -MH - Humans -MH - Kidney/*innervation -MH - Pulmonary Veins/physiopathology/surgery -MH - Sympathectomy/*methods -MH - Sympathetic Nervous System/physiopathology/*surgery -MH - Treatment Outcome -EDAT- 2013/06/14 06:00 -MHDA- 2014/02/20 06:00 -CRDT- 2013/06/05 06:00 -PHST- 2013/06/05 06:00 [entrez] -PHST- 2013/06/14 06:00 [pubmed] -PHST- 2014/02/20 06:00 [medline] -AID - EIJV9SRA19 [pii] -AID - 10.4244/EIJV9SRA19 [doi] -PST - ppublish -SO - EuroIntervention. 2013 May;9 Suppl R:R110-6. doi: 10.4244/EIJV9SRA19. - -PMID- 19719492 -OWN - NLM -STAT- MEDLINE -DCOM- 20091112 -LR - 20220409 -IS - 1540-8159 (Electronic) -IS - 0147-8389 (Linking) -VI - 32 -IP - 9 -DP - 2009 Sep -TI - Sudden cardiac death in China. -PG - 1159-62 -LID - 10.1111/j.1540-8159.2009.02458.x [doi] -AB - Preliminary data suggest that sudden cardiac death (SCD) occur at a rate of - 41.8/100,000 population in China, accounting for over 544,000 deaths annually. - While about 70% of SCD are due to underlying coronary artery disease, several - specific cardiomyopathies and hereditary heart diseases are endemic in China. - Pharmacological treatment is the main treatment strategy, and both community - resuscitation and implantable cardioverter defibrillator therapy are limited by - socioeconomic conditions. There is increasing use of catheter ablation for some - ventricular arrhythmias. A national project has been started recently for SCD - prevention. -FAU - Zhang, Shu -AU - Zhang S -AD - Fu Wai Cardiovascular Hospital, Chinese Academy of Medical Sciences and Peking - Union Medical College, Beijing, PR China. zsfuwai@vip.163.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Pacing Clin Electrophysiol -JT - Pacing and clinical electrophysiology : PACE -JID - 7803944 -SB - IM -MH - China -MH - Death, Sudden, Cardiac/*prevention & control -MH - Defibrillators, Implantable/*statistics & numerical data -MH - Heart Failure/*mortality/*prevention & control -MH - Humans -MH - Pacemaker, Artificial/*statistics & numerical data -MH - Practice Patterns, Physicians'/*statistics & numerical data -MH - Survival Analysis -MH - Survival Rate -RF - 22 -EDAT- 2009/09/02 06:00 -MHDA- 2009/11/13 06:00 -CRDT- 2009/09/02 09:00 -PHST- 2009/09/02 09:00 [entrez] -PHST- 2009/09/02 06:00 [pubmed] -PHST- 2009/11/13 06:00 [medline] -AID - PACE2458 [pii] -AID - 10.1111/j.1540-8159.2009.02458.x [doi] -PST - ppublish -SO - Pacing Clin Electrophysiol. 2009 Sep;32(9):1159-62. doi: - 10.1111/j.1540-8159.2009.02458.x. - -PMID- 18324696 -OWN - NLM -STAT- MEDLINE -DCOM- 20080529 -LR - 20161124 -IS - 1522-726X (Electronic) -IS - 1522-1946 (Linking) -VI - 71 -IP - 6 -DP - 2008 May 1 -TI - Recent advances in hemodynamics: noncoronary applications of a pressure sensor - angioplasty guidewire. -PG - 748-58 -LID - 10.1002/ccd.21505 [doi] -AB - The use of the pressure sensor coronary guidewire is expanding into the - peripheral circulation as well as into the realm of valvular heart disease. Small - mechanistic studies and case reports have described the use of pressure wire - technology in the renal and femoral arteries as well as in mechanical aortic - valves. The use of this technology to measure hemodynamically significant - stenoses in noncoronary locations will be discussed and a review of basic and - more advanced hemodynamics in relation to problems encountered in clinical - practice will be provided. -CI - 2008 Wiley-Liss, Inc. -FAU - Cavendish, Jeffrey J -AU - Cavendish JJ -AD - Department of Cardiology, Naval Medical Center San Diego, San Diego, California, - USA. jeffrey.cavendish@med.navy.mil -FAU - Carter, Luther I -AU - Carter LI -FAU - Tsimikas, Sotirios -AU - Tsimikas S -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Catheter Cardiovasc Interv -JT - Catheterization and cardiovascular interventions : official journal of the - Society for Cardiac Angiography & Interventions -JID - 100884139 -SB - IM -MH - Angioplasty/*instrumentation -MH - Aortic Diseases/diagnosis/physiopathology -MH - Arterial Occlusive Diseases/*diagnosis/diagnostic imaging/physiopathology -MH - Blood Pressure -MH - Constriction, Pathologic -MH - Electrocardiography -MH - Equipment Design -MH - Femoral Artery/physiopathology -MH - Heart Valve Diseases/*diagnosis/physiopathology -MH - *Hemodynamics -MH - Humans -MH - Iliac Artery/physiopathology -MH - Models, Cardiovascular -MH - Peripheral Vascular Diseases/*diagnosis/diagnostic imaging/physiopathology -MH - Radiography -MH - Renal Artery Obstruction/diagnosis/physiopathology -MH - Severity of Illness Index -MH - *Transducers, Pressure -RF - 20 -EDAT- 2008/03/08 09:00 -MHDA- 2008/05/30 09:00 -CRDT- 2008/03/08 09:00 -PHST- 2008/03/08 09:00 [pubmed] -PHST- 2008/05/30 09:00 [medline] -PHST- 2008/03/08 09:00 [entrez] -AID - 10.1002/ccd.21505 [doi] -PST - ppublish -SO - Catheter Cardiovasc Interv. 2008 May 1;71(6):748-58. doi: 10.1002/ccd.21505. - -PMID- 17005273 -OWN - NLM -STAT- MEDLINE -DCOM- 20070822 -LR - 20191210 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 118 -IP - 2 -DP - 2007 May 31 -TI - Marijuana as a trigger of cardiovascular events: speculation or scientific - certainty? -PG - 141-4 -AB - Marijuana is the most widely used illicit substance in the United States. - Cardiovascular complications in association with marijuana use have been reported - during the past three decades. In view of the elevated public interest in this - drug's role in pharmacotherapy in the recent years and the aging population of - long-term marijuana users from the late 1960s, encounters with marijuana-related - cardiovascular adversities may be silently on the rise. The purpose of this - article is to increase awareness of the potential of marijuana to lead to - cardiovascular disease. Here, we will discuss the physiologic effects of - marijuana and include a comprehensive review of the studies and case reports that - provide supportive evidence for marijuana as a trigger of adverse cardiovascular - events, including tachyarrhythmias, acute coronary syndrome, vascular - complications, and even congenital heart defects. -FAU - Aryana, Arash -AU - Aryana A -AD - Cardiac Arrhythmia Service, Massachusetts General Hospital, 55 Fruit - Street-GRB-109, Boston, MA 02114, USA. aaryana@partners.org -FAU - Williams, Mark A -AU - Williams MA -LA - eng -PT - Journal Article -PT - Review -DEP - 20060926 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Illicit Drugs) -RN - 0 (Psychotropic Drugs) -RN - 7J8897W37S (Dronabinol) -SB - IM -MH - Adult -MH - Angina Pectoris/chemically induced -MH - Cannabis/*adverse effects -MH - Cardiovascular Diseases/*chemically induced -MH - Dronabinol/pharmacology -MH - Female -MH - Heart Defects, Congenital/chemically induced -MH - Humans -MH - Illicit Drugs/adverse effects/pharmacology -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/chemically induced -MH - Paternal Exposure/adverse effects -MH - Psychotropic Drugs/pharmacology -MH - Tachycardia/chemically induced -MH - Vasoconstriction/drug effects -RF - 43 -EDAT- 2006/09/29 09:00 -MHDA- 2007/08/23 09:00 -CRDT- 2006/09/29 09:00 -PHST- 2006/02/06 00:00 [received] -PHST- 2006/08/03 00:00 [revised] -PHST- 2006/08/03 00:00 [accepted] -PHST- 2006/09/29 09:00 [pubmed] -PHST- 2007/08/23 09:00 [medline] -PHST- 2006/09/29 09:00 [entrez] -AID - S0167-5273(06)00778-9 [pii] -AID - 10.1016/j.ijcard.2006.08.001 [doi] -PST - ppublish -SO - Int J Cardiol. 2007 May 31;118(2):141-4. doi: 10.1016/j.ijcard.2006.08.001. Epub - 2006 Sep 26. - -PMID- 16969165 -OWN - NLM -STAT- MEDLINE -DCOM- 20070406 -LR - 20060913 -IS - 1040-8703 (Print) -IS - 1040-8703 (Linking) -VI - 18 -IP - 5 -DP - 2006 Oct -TI - Advances in pediatric heart transplantation. -PG - 512-7 -AB - PURPOSE OF REVIEW: Heart transplantation has become a reasonable treatment option - for pediatric patients with end-stage heart failure or complex congenital cardiac - defects not amenable to conventional surgical intervention. This review will - summarize the current state of pediatric cardiac transplantation and review - recent advances leading to new therapies. RECENT FINDINGS: Improvements in early - mortality after cardiac transplantation have occurred consistently over time - since the 1980s, short-term survival rates are high, and most patients enjoy an - excellent quality of life with minimal restrictions. The reduction of late - mortality is still a major challenge, however, largely as a result of - transplant-related coronary artery disease causing chronic graft failure and - arrhythmogenic sudden death. Additional causes of morbidity and mortality - occurring late after transplantation include renal dysfunction related to chronic - immunosuppressive therapy with calcineurin inhibitors (tacrolimus or - cyclosporine) and posttransplant lymphoproliferative disorders related to chronic - immunosuppression. Newer agents (sirolimus, everolimus) have shown promise in - immunosuppressive regimens that may alter the development or progression of - long-term complications. SUMMARY: New immunosuppressive agents allow alterations - in drug regimens to minimize renal complications, and may influence the incidence - and progression of transplant vasculopathy. Recent studies on posttransplant - lymphoproliferative disorders should result in earlier diagnosis and therapy. -FAU - Schowengerdt, Kenneth O -AU - Schowengerdt KO -AD - Saint Louis University Health Sciences Center and Cardinal Glennon Children's - Medical Center, 1465 S. Grand Boulevard, St Louis, MO 63104, USA. schowko@slu.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Pediatr -JT - Current opinion in pediatrics -JID - 9000850 -SB - IM -MH - Child -MH - *Heart Transplantation/adverse effects -MH - Humans -RF - 47 -EDAT- 2006/09/14 09:00 -MHDA- 2007/04/07 09:00 -CRDT- 2006/09/14 09:00 -PHST- 2006/09/14 09:00 [pubmed] -PHST- 2007/04/07 09:00 [medline] -PHST- 2006/09/14 09:00 [entrez] -AID - 00008480-200610000-00007 [pii] -AID - 10.1097/01.mop.0000245351.37713.13 [doi] -PST - ppublish -SO - Curr Opin Pediatr. 2006 Oct;18(5):512-7. doi: 10.1097/01.mop.0000245351.37713.13. - -PMID- 21689449 -OWN - NLM -STAT- MEDLINE -DCOM- 20120626 -LR - 20250626 -IS - 1471-2261 (Electronic) -IS - 1471-2261 (Linking) -VI - 11 -DP - 2011 Jun 20 -TI - Routine invasive management after fibrinolysis in patients with ST-elevation - myocardial infarction: a systematic review of randomized clinical trials. -PG - 34 -LID - 10.1186/1471-2261-11-34 [doi] -AB - BACKGROUND: Patients with ST-elevation myocardial infarction (STEMI) treated with - fibrinolysis are increasingly, and ever earlier, referred for routine coronary - angiography and where feasible, undergo percutaneous coronary intervention (PCI). - We sought to examine the randomized clinical trials (RCTs) on which this approach - is based. METHODS: We systematically searched EMBASE, Medline, and references of - relevant studies. All contemporary RCTs (published since 1995) that compared - systematic invasive management of STEMI patients after fibrinolysis with standard - care were included. Relevant study design and clinical outcome data were - extracted. RESULTS: Nine RCTs that randomized a total of 3320 patients were - identified. All suggested a benefit from routine early invasive management. They - were individually reviewed but important design variations precluded a formal - quantitative meta-analysis. Importantly, several trials did not compare a routine - practice of invasive management after fibrinolysis with a more selective - 'ischemia-guided' approach but rather compared an early versus later routine - invasive strategy. In the other studies, recourse to subsequent invasive - management in the usual care group varied widely. Comparison of the effectiveness - of a routine invasive approach to usual care was also limited by asymmetric use - of a second anti-platelet agent, differing enzyme definitions of reinfarction - occurring spontaneously versus as a complication of PCI, a preponderance of the - 'soft' outcome of recurrent ischemia in the combined primary endpoint, and an - interpretative bias when invasive procedures on follow-up were tallied as an - endpoint without considering initial invasive procedures performed in the routine - invasive arm. CONCLUSIONS: Due to important methodological limitations, - definitive RCT evidence in favor of routine invasive management following - fibrinolysis in patients with STEMI is presently lacking. -CI - © 2011 Bogaty et al; licensee BioMed Central Ltd. -FAU - Bogaty, Peter -AU - Bogaty P -AD - Institut universitaire de cardiologie et pneumologie de Québec, Quebec, Canada. - peter.bogaty@fmed.ulaval.ca -FAU - Filion, Kristian B -AU - Filion KB -FAU - Brophy, James M -AU - Brophy JM -LA - eng -PT - Case Reports -PT - Comparative Study -PT - Journal Article -PT - Systematic Review -DEP - 20110620 -PL - England -TA - BMC Cardiovasc Disord -JT - BMC cardiovascular disorders -JID - 100968539 -RN - 0 (Fibrinolytic Agents) -SB - IM -MH - Aged -MH - Disease Management -MH - *Fibrinolysis/drug effects -MH - Fibrinolytic Agents/pharmacology/*therapeutic use -MH - Heart Atria/physiopathology -MH - Humans -MH - Male -MH - Myocardial Infarction/*diagnosis/*drug therapy/epidemiology -MH - Randomized Controlled Trials as Topic/*methods -MH - Treatment Outcome -PMC - PMC3145591 -EDAT- 2011/06/22 06:00 -MHDA- 2012/06/27 06:00 -PMCR- 2011/06/20 -CRDT- 2011/06/22 06:00 -PHST- 2011/05/16 00:00 [received] -PHST- 2011/06/20 00:00 [accepted] -PHST- 2011/06/22 06:00 [entrez] -PHST- 2011/06/22 06:00 [pubmed] -PHST- 2012/06/27 06:00 [medline] -PHST- 2011/06/20 00:00 [pmc-release] -AID - 1471-2261-11-34 [pii] -AID - 10.1186/1471-2261-11-34 [doi] -PST - epublish -SO - BMC Cardiovasc Disord. 2011 Jun 20;11:34. doi: 10.1186/1471-2261-11-34. - -PMID- 17975790 -OWN - NLM -STAT- MEDLINE -DCOM- 20080215 -LR - 20131121 -IS - 1522-726X (Electronic) -IS - 1522-1946 (Linking) -VI - 71 -IP - 1 -DP - 2008 Jan 1 -TI - Contrast-induced nephropathy. -PG - 62-72 -AB - Contrast induced nephropathy (CIN) is an iatrogenic disorder, resulting from - exposure to contrast media. Contrast-induced hemodynamic and direct cytotoxic - effects on renal structures are highly evident in its pathogenesis, whereas other - mechanisms are still poorly understood. CIN is typically defined as an increase - in serum creatinine by either > or =0.5 mg/dl or by > or =25% from baseline - within the first 2-3 days after contrast administration. Although rare in the - general population, CIN has a high incidence in patients with an underlying renal - disorder, in diabetics, and the elderly. The risk factors are synergistic in - their ability to produce CIN. The best way to prevent CIN is to identify the - patients at risk and to provide adequate peri-procedural hydration. The role of - various drugs in prevention of CIN is still controversial and warrants future - studies. Despite remaining uncertainty regarding the degree of nephrotoxicity - produced by various contrast agents, in current practice non-ionic low-osmolar - contrast media are preferred over the high-osmolar contrast media in patients - with renal impairment. -CI - Copyright 2007 Wiley-Liss, Inc. -FAU - Pucelikova, Tereza -AU - Pucelikova T -AD - Cardiovascular Research Foundation, 55 East 59th Street, 6th Floor, New York, New - York 10022, USA. -FAU - Dangas, George -AU - Dangas G -FAU - Mehran, Roxana -AU - Mehran R -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Catheter Cardiovasc Interv -JT - Catheterization and cardiovascular interventions : official journal of the - Society for Cardiac Angiography & Interventions -JID - 100884139 -RN - 0 (Calcium Channel Blockers) -RN - 0 (Contrast Media) -RN - 0 (Free Radical Scavengers) -RN - 0 (Phosphodiesterase Inhibitors) -RN - AYI8EX34EU (Creatinine) -RN - C137DTR5RG (Theophylline) -RN - INU8H2KAWG (Fenoldopam) -RN - WYQ7N0BPYC (Acetylcysteine) -SB - IM -MH - Acetylcysteine/therapeutic use -MH - Acute Kidney Injury/blood/*chemically induced/epidemiology/prevention & control -MH - Calcium Channel Blockers/therapeutic use -MH - Contrast Media/administration & dosage/*adverse effects -MH - Coronary Angiography/*adverse effects -MH - Creatinine/blood -MH - Diabetes Mellitus/epidemiology -MH - Fenoldopam/therapeutic use -MH - Free Radical Scavengers/therapeutic use -MH - Heart Failure/epidemiology -MH - Humans -MH - Iatrogenic Disease -MH - Kidney Diseases/epidemiology -MH - Kidney Transplantation -MH - Multivariate Analysis -MH - Osmolar Concentration -MH - Phosphodiesterase Inhibitors/therapeutic use -MH - Prognosis -MH - Renal Dialysis -MH - Risk Factors -MH - Theophylline/therapeutic use -RF - 95 -EDAT- 2007/11/03 09:00 -MHDA- 2008/02/19 09:00 -CRDT- 2007/11/03 09:00 -PHST- 2007/11/03 09:00 [pubmed] -PHST- 2008/02/19 09:00 [medline] -PHST- 2007/11/03 09:00 [entrez] -AID - 10.1002/ccd.21207 [doi] -PST - ppublish -SO - Catheter Cardiovasc Interv. 2008 Jan 1;71(1):62-72. doi: 10.1002/ccd.21207. - -PMID- 21233190 -OWN - NLM -STAT- MEDLINE -DCOM- 20110307 -LR - 20220408 -IS - 1535-5667 (Electronic) -IS - 0161-5505 (Linking) -VI - 52 -IP - 2 -DP - 2011 Feb -TI - Cardiac dedicated ultrafast SPECT cameras: new designs and clinical implications. -PG - 210-7 -LID - 10.2967/jnumed.110.081323 [doi] -AB - Myocardial perfusion imaging (MPI) using nuclear cardiology techniques has been - widely applied in clinical practice because of its well-documented value in the - diagnosis and prognosis of coronary artery disease. Industry has developed - innovative designs for dedicated cardiac SPECT cameras that constrain the entire - detector area to imaging just the heart. New software that recovers image - resolution and limits image noise has also been implemented. These SPECT - innovations are resulting in shortened study times or reduced radiation doses to - patients, promoting easier scheduling, higher patient satisfaction, and, - importantly, higher image quality. This article describes these cardiocentric - SPECT software and hardware innovations, which provide a strong foundation for - the continued success of myocardial perfusion SPECT. -FAU - Garcia, Ernest V -AU - Garcia EV -AD - Department of Radiology, Emory University School of Medicine, Atlanta, Georgia - 33022, USA. ernest.garcia@emory.edu -FAU - Faber, Tracy L -AU - Faber TL -FAU - Esteves, Fabio P -AU - Esteves FP -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110113 -PL - United States -TA - J Nucl Med -JT - Journal of nuclear medicine : official publication, Society of Nuclear Medicine -JID - 0217410 -SB - IM -MH - Equipment Design -MH - Heart/*diagnostic imaging -MH - Heart Diseases/*diagnostic imaging -MH - Humans -MH - Image Processing, Computer-Assisted/trends -MH - Myocardial Perfusion Imaging -MH - Reproducibility of Results -MH - Software -MH - Tomography, Emission-Computed, Single-Photon/*instrumentation/trends -EDAT- 2011/01/15 06:00 -MHDA- 2011/03/08 06:00 -CRDT- 2011/01/15 06:00 -PHST- 2011/01/15 06:00 [entrez] -PHST- 2011/01/15 06:00 [pubmed] -PHST- 2011/03/08 06:00 [medline] -AID - jnumed.110.081323 [pii] -AID - 10.2967/jnumed.110.081323 [doi] -PST - ppublish -SO - J Nucl Med. 2011 Feb;52(2):210-7. doi: 10.2967/jnumed.110.081323. Epub 2011 Jan - 13. - -PMID- 22322550 -OWN - NLM -STAT- MEDLINE -DCOM- 20130903 -LR - 20120210 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 13 -IP - 2 -DP - 2012 Feb -TI - [Revascularization of the hibernated myocardium: a clinical problem still - unsolved]. -PG - 102-9 -LID - 10.1714/1021.11143 [doi] -AB - The mid- and long-term outcome of revascularization procedures is still uncertain - in patients with chronic left ventricular systolic dysfunction due to coronary - artery disease. The identification of dysfunctional myocardial segments with - residual viability that can improve after revascularization is pivotal for - further patient management. Hibernating myocardium (chronically dysfunctional but - still viable tissue) can be identified by positron emission tomography and - cardiac magnetic resonance and its presence and extent can predict functional - recovery after revascularization. Before beta-blockers were introduced as routine - care for heart failure, surgical revascularization appeared to improve survival - in these patients. Nowadays, novel medical treatments and devices such as cardiac - resynchronization therapy and implantable cardioverter-defibrillators have - improved prognosis of these patients and their use is supported by a number of - clinical trials. A recently concluded randomized trial, the STICH (Surgical - Treatment for Ischemic Heart Failure) trial, has assessed the prognostic benefit - derived from revascularization added to optimal medical therapy in patients with - ischemic left ventricular dysfunction. This is an overview of the - pathophysiological mechanisms as well as the main clinical studies and - meta-analyses that have addressed this issue in the past four decades. - Furthermore, a brief proposal for a randomized trial to assess effect on - prognosis of revascularization of hibernating myocardium will be presented. -FAU - Ammirati, Enrico -AU - Ammirati E -AD - Dipartimento Cardio-Toraco-Vascolare, Universitta Vita-Salute e Istituto - Scientifico, San Raffaele, Milano. -FAU - Guida, Valentina -AU - Guida V -FAU - Rimoldi, Ornella E -AU - Rimoldi OE -FAU - Camici, Paolo G -AU - Camici PG -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - Rivascolarizzazione del miocardio ibernato: un problema clinico ancora irrisolto. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -SB - IM -MH - Algorithms -MH - Chronic Disease -MH - Humans -MH - *Myocardial Revascularization -MH - Myocardial Stunning/*surgery -MH - Randomized Controlled Trials as Topic -MH - Ventricular Dysfunction, Left/surgery -EDAT- 2012/02/11 06:00 -MHDA- 2013/09/04 06:00 -CRDT- 2012/02/11 06:00 -PHST- 2012/02/11 06:00 [entrez] -PHST- 2012/02/11 06:00 [pubmed] -PHST- 2013/09/04 06:00 [medline] -AID - 10.1714/1021.11143 [doi] -PST - ppublish -SO - G Ital Cardiol (Rome). 2012 Feb;13(2):102-9. doi: 10.1714/1021.11143. - -PMID- 21426247 -OWN - NLM -STAT- MEDLINE -DCOM- 20110913 -LR - 20131121 -IS - 1525-6049 (Electronic) -IS - 0886-022X (Linking) -VI - 33 -IP - 4 -DP - 2011 -TI - Syndrome of inappropriate antidiuretic hormone in association with amiodarone - therapy: a case report and review of literature. -PG - 456-8 -LID - 10.3109/0886022X.2011.565138 [doi] -AB - BACKGROUND: Amiodarone is a class III antiarrhythmic agent that is widely used in - the treatment of a variety of arrhythmias. Several different systemic side - effects are reported after use of this medication. In this article, we report a - case that had developed syndrome of inappropriate antidiuretic hormone (SIADH) - after starting treatment with this agent. CASE REPORT: The patient is a - 66-year-old male with past medical history of hypertension, hyperlipidemia, - coronary artery disease, and class III New York Heart Association congestive - heart failure who presented with monomorphic nonsustained ventricular - tachycardia. A loading dose of amiodarone followed by maintenance dose was - started. Baseline serum sodium of 138 mmol/L on admission decreased to 119 mmol/L - by day 7, and a diagnosis of SIADH was made. The patient was not taking any other - medication known to cause SIADH, nor had any such comorbidity to explain it. - Serum sodium increased to 133 and 138 mmol/L, respectively, after 16 and 33 days - from discontinuation of amiodarone. CONCLUSION: SIADH is a rare but serious side - effect of amiodarone and practicing physicians should be aware of this - complication, particularly after loading dose of the medication. -FAU - Afshinnia, Farsad -AU - Afshinnia F -AD - Department of Internal Medicine, Ann Arbor VA Medical Center, University of - Michigan Health System, Ann Arbor, MI 48109-5000, USA. fafshin@med.umich.edu -FAU - Sheth, Neil -AU - Sheth N -FAU - Perlman, Rachel -AU - Perlman R -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20110323 -PL - England -TA - Ren Fail -JT - Renal failure -JID - 8701128 -RN - 0 (Anti-Arrhythmia Agents) -RN - N3RQ532IUT (Amiodarone) -SB - IM -MH - Aged -MH - Amiodarone/*adverse effects -MH - Anti-Arrhythmia Agents/*adverse effects -MH - Humans -MH - Iatrogenic Disease -MH - Inappropriate ADH Syndrome/*chemically induced -MH - Male -EDAT- 2011/03/24 06:00 -MHDA- 2011/09/14 06:00 -CRDT- 2011/03/24 06:00 -PHST- 2011/03/24 06:00 [entrez] -PHST- 2011/03/24 06:00 [pubmed] -PHST- 2011/09/14 06:00 [medline] -AID - 10.3109/0886022X.2011.565138 [doi] -PST - ppublish -SO - Ren Fail. 2011;33(4):456-8. doi: 10.3109/0886022X.2011.565138. Epub 2011 Mar 23. - -PMID- 26558011 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20151111 -LR - 20220311 -IS - 2090-598X (Print) -IS - 2090-5998 (Electronic) -IS - 2090-598X (Linking) -VI - 10 -IP - 2 -DP - 2012 Jun -TI - Erectile dysfunction in Arab countries. Part II: Diagnosis and treatment. -PG - 104-9 -LID - 10.1016/j.aju.2012.02.001 [doi] -AB - OBJECTIVE: To review local published data on the diagnosis and treatment of - erectile dysfunction (ED) in Arab countries. METHODS: MEDLINE was searched for - English-language articles published from 2000 to 2011, using the search terms - 'Arab countries', 'sexual dysfunction', 'diagnosis' and 'treatment'. RESULTS: In - all, 86 articles were found to be relevant to this review; only a few had a high - level of evidence and the remaining studies used an uncontrolled design. Several - local studies were consistent with previous reports showing that a customised - diagnostic pathway, with full consideration of the patient's goals, is adopted by - most clinicians to treat ED. For an effective treatment, the evaluation methods - should answer important questions about the aetiology and severity of ED, as well - as the patient's and partner's goals and expectations. As ED is known to be - associated with many common medical comorbidities and medications, careful - questioning can yield information about peripheral vascular disease, coronary - artery disease, diabetes, hypertension, dyslipidaemia, and tobacco and alcohol - use. The presence of psychological, neurological or chronic debilitating diseases - can direct further evaluation. CONCLUSION: The methods used for the diagnosis and - treatment of ED need more investigation, especially in Arab countries. Only a few - studies addressed the results of different methods of investigating and treating - ED among Arab men. -FAU - El-Sakka, Ahmed I -AU - El-Sakka AI -AD - Department of Urology, Suez Canal University, Ismailia, Egypt. -LA - eng -PT - Journal Article -PT - Review -DEP - 20120315 -PL - United States -TA - Arab J Urol -JT - Arab journal of urology -JID - 101562480 -PMC - PMC4442901 -OTO - NOTNLM -OT - Arab countries -OT - DM, diabetes mellitus -OT - Diagnosis -OT - ED, erectile dysfunction -OT - EECP, enhanced external counterpulsation -OT - IHD, ischaemic heart disease -OT - IIEF, International Index of Erectile Function -OT - PDE-5, phosphodiesterase-5 -OT - PE, premature ejaculation -OT - PGE1, prostaglandin E1 -OT - Sexual dysfunction -OT - Treatment -EDAT- 2012/06/01 00:00 -MHDA- 2012/06/01 00:01 -PMCR- 2012/03/15 -CRDT- 2015/11/12 06:00 -PHST- 2012/01/22 00:00 [received] -PHST- 2012/02/14 00:00 [revised] -PHST- 2012/02/14 00:00 [accepted] -PHST- 2015/11/12 06:00 [entrez] -PHST- 2012/06/01 00:00 [pubmed] -PHST- 2012/06/01 00:01 [medline] -PHST- 2012/03/15 00:00 [pmc-release] -AID - S2090-598X(12)00017-4 [pii] -AID - 10.1016/j.aju.2012.02.001 [doi] -PST - ppublish -SO - Arab J Urol. 2012 Jun;10(2):104-9. doi: 10.1016/j.aju.2012.02.001. Epub 2012 Mar - 15. - -PMID- 16970057 -OWN - NLM -STAT- MEDLINE -DCOM- 20061207 -LR - 20170511 -IS - 0001-5385 (Print) -IS - 0001-5385 (Linking) -VI - 61 -IP - 4 -DP - 2006 Aug -TI - Non-invasive methods in differentiating ischaemic from non-ischaemic - cardiomyopathy. A review paper. -PG - 454-62 -AB - Chronic heart failure is a common disorder associated with high mortality and - morbidity. Patients' numbers and the burden placed on health care services - increase as the average age of the population rises. Non-invasive imaging plays a - central role in the correct diagnosis of heart failure, the determination of - aetiology and prognosis, as well as the monitoring of ongoing therapy. In this - review paper we critically summarize techniques that differentiate ischaemic from - non-ischaemic cardiomyopathy. Coronary angiography has been used as the primary - method for distinguishing ischaemic from non-ischaemic cardiomyopathy; while - studies utilizing echocardiography, myocardial perfusion imaging or electron - computed tomography and positron emission tomography, have played a substantial - role. More recently, CMR and multislice computed tomography have demonstrated - ability in initial functional assessment and in the determination of secondary - causes of heart failure. -FAU - Chrysohoou, Christina -AU - Chrysohoou C -AD - Cardiology Clinic, Veterans Affairs Medical Center, Washington, DC, USA. - chrysohoou@usa.net -FAU - Greenberg, Michael -AU - Greenberg M -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - England -TA - Acta Cardiol -JT - Acta cardiologica -JID - 0370570 -SB - IM -MH - Cardiomyopathy, Dilated/complications/*diagnosis/mortality/therapy -MH - Chronic Disease -MH - Diagnosis, Differential -MH - *Diagnostic Imaging/methods -MH - Humans -MH - *Monitoring, Physiologic/methods -MH - Myocardial Ischemia/complications/*diagnosis/mortality/therapy -MH - Prognosis -RF - 72 -EDAT- 2006/09/15 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/09/15 09:00 -PHST- 2006/09/15 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/09/15 09:00 [entrez] -AID - 10.2143/AC.61.4.2017308 [doi] -PST - ppublish -SO - Acta Cardiol. 2006 Aug;61(4):454-62. doi: 10.2143/AC.61.4.2017308. - -PMID- 21464638 -OWN - NLM -STAT- MEDLINE -DCOM- 20110726 -LR - 20110405 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 19 -IP - 3 -DP - 2011 May-Jun -TI - Neurologic and cardiac benefits of therapeutic hypothermia. -PG - 108-14 -LID - 10.1097/CRD.0b013e31820828af [doi] -AB - Numerous studies have shown the favorable effects of lowering the core - temperature of the body in various conditions such as acute myocardial - infarction, acute cerebrovascular disease, acute lung injury, and acute spinal - cord injury. Therapeutic hypothermia (TH) works at different molecular and - cellular levels. TH improves oxygen supply to ischemic areas and increases blood - flow by decreasing vasoconstriction, as well as oxygen consumption, glucose - utilization, lactate concentration, intracranial pressure, heart rate, cardiac - output, and plasma insulin levels. TH has been shown to improve neurologic - outcome in acute cerebrovascular accidents. Furthermore, recent studies revealed - that TH is a useful method of neuroprotection against ischemic neuronal injury - after cardiac arrest. TH in out-of-hospital cardiac arrest is becoming a standard - practice nationwide. Further studies need to be performed to develop a better - understanding of the benefits and detrimental effects of TH, to identify the most - efficacious TH strategy, and the candidates most likely to derive benefit from - the procedure. Although many animal studies have demonstrated benefit, larger - human clinical trials are recommended to investigate the beneficial effect of TH - on reducing myocardial infarction size and coronary reperfusion injuries. -CI - © 2011 Lippincott Williams & Wilkins -FAU - Azmoon, Shah -AU - Azmoon S -AD - Division of Cardiology, Department of Medicine, New York Medical College, - Westchester Medical Center, Valhalla, NY 10595, USA. syntaxmax@aol.com -FAU - Demarest, Caitlin -AU - Demarest C -FAU - Pucillo, Anthony L -AU - Pucillo AL -FAU - Hjemdahl-Monsen, Craig -AU - Hjemdahl-Monsen C -FAU - Kay, Richard -AU - Kay R -FAU - Ahmadi, Naser -AU - Ahmadi N -FAU - Aronow, Wilbert S -AU - Aronow WS -FAU - Frishman, William H -AU - Frishman WH -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -SB - IM -MH - Heart Arrest/*therapy -MH - Humans -MH - *Hypothermia, Induced -MH - Nervous System -MH - Treatment Outcome -EDAT- 2011/04/06 06:00 -MHDA- 2011/07/27 06:00 -CRDT- 2011/04/06 06:00 -PHST- 2011/04/06 06:00 [entrez] -PHST- 2011/04/06 06:00 [pubmed] -PHST- 2011/07/27 06:00 [medline] -AID - 00045415-201105000-00002 [pii] -AID - 10.1097/CRD.0b013e31820828af [doi] -PST - ppublish -SO - Cardiol Rev. 2011 May-Jun;19(3):108-14. doi: 10.1097/CRD.0b013e31820828af. - -PMID- 16703232 -OWN - NLM -STAT- MEDLINE -DCOM- 20060908 -LR - 20170214 -IS - 1089-2532 (Print) -IS - 1089-2532 (Linking) -VI - 10 -IP - 1 -DP - 2006 Mar -TI - Volatile anesthetics and cardiac function. -PG - 33-42 -AB - All volatile anesthetics have been shown to induce a dose-dependent decrease in - myocardial contractility and cardiac loading conditions. These depressant effects - decrease myocardial oxygen demand and may, therefore, have a beneficial role on - the myocardial oxygen balance during myocardial ischemia. Recently, experimental - evidence has clearly demonstrated that in addition to these indirect protective - effects, volatile anesthetic agents also have direct protective properties - against reversible and irreversible ischemic myocardial damage. These properties - have not only been related to a direct preconditioning effect but also to an - effect on the extent of reperfusion injury. The implementation of these - properties during clinical anesthesia can provide an additional tool in the - treatment or prevention, or both, of ischemic cardiac dysfunction in the - perioperative period. In the clinical practice, these effects should be - associated with improved cardiac function, finally resulting in a better outcome - in patients with coronary artery disease. The potential application of these - protective properties of volatile anesthetic agents in clinical practice is the - subject of ongoing research. This review summarizes the current knowledge on this - subject. -FAU - De Hert, Stefan G -AU - De Hert SG -AD - Department of Anesthesiology, University of Antwerp, Belgium. - stefan.dehert@ua.ac.be -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Semin Cardiothorac Vasc Anesth -JT - Seminars in cardiothoracic and vascular anesthesia -JID - 9807630 -RN - 0 (Anesthetics, Inhalation) -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Anesthetics, Inhalation/*pharmacology/therapeutic use -MH - *Cardiotonic Agents -MH - Clinical Trials as Topic -MH - Heart/*drug effects -MH - Heart Function Tests -MH - Humans -MH - Ischemic Preconditioning, Myocardial -MH - Myocardial Reperfusion Injury/prevention & control -RF - 22 -EDAT- 2006/05/17 09:00 -MHDA- 2006/09/09 09:00 -CRDT- 2006/05/17 09:00 -PHST- 2006/05/17 09:00 [pubmed] -PHST- 2006/09/09 09:00 [medline] -PHST- 2006/05/17 09:00 [entrez] -AID - 10.1177/108925320601000107 [doi] -PST - ppublish -SO - Semin Cardiothorac Vasc Anesth. 2006 Mar;10(1):33-42. doi: - 10.1177/108925320601000107. - -PMID- 20609882 -OWN - NLM -STAT- MEDLINE -DCOM- 20100719 -LR - 20161125 -IS - 1557-8275 (Electronic) -IS - 0033-8389 (Linking) -VI - 48 -IP - 2 -DP - 2010 Mar -TI - Pediatric computed tomographic angiography: imaging the cardiovascular system - gently. -PG - 439-67, x -LID - 10.1016/j.rcl.2010.03.005 [doi] -AB - Whether congenital or acquired, timely recognition and management of disease is - imperative, as hemodynamic alterations in blood flow, tissue perfusion, and - cellular oxygenation can have profound effects on organ function, growth and - development, and quality of life for the pediatric patient. Ensuring safe - computed tomographic angiography (CTA) practice and "gentle" pediatric imaging - requires the cardiovascular imager to have sound understanding of CTA advantages, - limitations, and appropriate indications as well as strong working knowledge of - acquisition principles and image post processing. From this vantage point, CTA - can be used as a useful adjunct along with the other modalities. This article - presents a summary of dose reduction CTA methodologies along with techniques the - authors have employed in clinical practice to achieve low-dose and ultralow-dose - exposure in pediatric CTA. CTA technical principles are discussed with an - emphasis on the low-dose methodologies and safe contrast medium delivery - strategies. Recommended parameters for currently available multidetector-row - computed tomography scanners are summarized alongside recommended radiation and - contrast medium parameters. In the second part of the article an overview of - pediatric CTA clinical applications is presented, illustrating low-dose and - ultra-low dose techniques, with an emphasis on the specific protocols. -CI - Copyright 2010 Elsevier Inc. All rights reserved. -FAU - Hellinger, Jeffrey C -AU - Hellinger JC -AD - Department of Radiology, The Children's Hospital of Philadelphia, University of - Pennsylvania School of Medicine, Philadelphia, PA, USA. - jeffrey.hellinger@yahoo.com -FAU - Pena, Andres -AU - Pena A -FAU - Poon, Michael -AU - Poon M -FAU - Chan, Frandics P -AU - Chan FP -FAU - Epelman, Monica -AU - Epelman M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Radiol Clin North Am -JT - Radiologic clinics of North America -JID - 0123703 -RN - 0 (Contrast Media) -SB - IM -MH - Abdomen/blood supply -MH - Adolescent -MH - Angiography/methods -MH - Cardiovascular System/*diagnostic imaging -MH - Child -MH - Child, Preschool -MH - Contrast Media/administration & dosage -MH - Coronary Angiography/methods -MH - Extremities/blood supply/diagnostic imaging -MH - Head/blood supply/diagnostic imaging -MH - Heart/diagnostic imaging -MH - Humans -MH - Image Processing, Computer-Assisted/methods -MH - Neck/blood supply/diagnostic imaging -MH - Pediatrics/*methods -MH - Pelvis/blood supply/diagnostic imaging -MH - Radiation Dosage -MH - Radiographic Image Enhancement/methods -MH - Radiography, Abdominal/methods -MH - Radiography, Thoracic/methods -MH - Thorax/blood supply -MH - Tomography, X-Ray Computed/*methods -MH - Whole Body Imaging/methods -RF - 15 -EDAT- 2010/07/09 06:00 -MHDA- 2010/07/20 06:00 -CRDT- 2010/07/09 06:00 -PHST- 2010/07/09 06:00 [entrez] -PHST- 2010/07/09 06:00 [pubmed] -PHST- 2010/07/20 06:00 [medline] -AID - S0033-8389(10)00028-X [pii] -AID - 10.1016/j.rcl.2010.03.005 [doi] -PST - ppublish -SO - Radiol Clin North Am. 2010 Mar;48(2):439-67, x. doi: 10.1016/j.rcl.2010.03.005. - -PMID- 18260942 -OWN - NLM -STAT- MEDLINE -DCOM- 20080311 -LR - 20170310 -IS - 0022-9040 (Print) -IS - 0022-9040 (Linking) -VI - 47 -IP - 10 -DP - 2007 -TI - [The role of noninvasive methods of investigation in diagnosis of - atherosclerosis]. -PG - 37-44 -AB - Visualization of the myocardium with the use of various high technologies gains - more and more important significance in diseases of cardiovascular system. Large - value for investigations of the heart and blood vessels have acquired methods of - echocardiography, magnetic resonance tomography, spiral computed tomography, as - well as large spectrum of methods of nuclear cardiology. Contemporary value of - instrumental methods of investigation for diagnostics of atherosclerosis is - discussed in this paper and diagnostic possibilities of various techniques for - assessment of the state of myocardium, pathological changes of vascular wall and - for visualization of atherosclerotic plaques (AP) are presented. Advantages and - drawbacks of methods, their complex application for objective analysis of changes - in AP and their clinical significance are considered. Special accent is made on - early diagnosis of pathological derangements, because full value information - allows making adequate decisions about subsequent curative measures. It is shown - that detection and evaluation of early signs of atherosclerosis appears to be - determining factor of efficacy of treatment. In patients without obvious symptoms - of ischemic heart disease or at the background of postinfarction cardiosclerosis - nuclear cardiology with assessment of myocardial perfusion by single photon - emission computed tomography and positron emission tomography (PET) appears - rather valuable for assessment of viability even when coronary arteries are - unchanged. Important significance for detection of cardiosclerosis has also - acquired spiral computed tomography, which allows to reveal calcium in blood - vessels. The use of multislice computed tomography in perspective might partially - replace coronary angiography especially for assessment of degree of stenoses and - patency of grafts. On initial stages of atherosclerosis information on AP - structure especially on the presence of inflammatory component is very important. - Definite successes become noticeable with application of magnetic resonance - tomography for detection of AP. However, probably, further perfection of - equipment and methodological approaches with the use of novel contrasts is - necessary. In this plane definite successes are achieved by PET and combined - examinations by methods of PET/CT integrating advantages of both techniques. -FAU - Belenkov, Iu N -AU - Belenkov IuN -AD - Cardiology Research Complex, ul. Tretiya Cherepkovskaya 15a, 121552 Moscow, - Russia. -FAU - Sergienko, V B -AU - Sergienko VB -LA - rus -PT - English Abstract -PT - Journal Article -PT - Review -PL - Russia (Federation) -TA - Kardiologiia -JT - Kardiologiia -JID - 0376351 -SB - IM -MH - Angiography/*methods -MH - Atherosclerosis/*diagnosis -MH - Diagnosis, Differential -MH - Echocardiography/*methods -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Positron-Emission Tomography/*methods -MH - Reproducibility of Results -MH - Tomography, Emission-Computed, Single-Photon/*methods -MH - Tomography, Spiral Computed/*methods -RF - 67 -EDAT- 2008/02/12 09:00 -MHDA- 2008/03/12 09:00 -CRDT- 2008/02/12 09:00 -PHST- 2008/02/12 09:00 [pubmed] -PHST- 2008/03/12 09:00 [medline] -PHST- 2008/02/12 09:00 [entrez] -PST - ppublish -SO - Kardiologiia. 2007;47(10):37-44. - -PMID- 19037230 -OWN - NLM -STAT- MEDLINE -DCOM- 20090610 -LR - 20090416 -IS - 1476-5527 (Electronic) -IS - 0950-9240 (Linking) -VI - 23 -IP - 5 -DP - 2009 May -TI - Hypertension and heart failure: a dysfunction of systole, diastole or both? -PG - 295-306 -LID - 10.1038/jhh.2008.141 [doi] -AB - The pathological myocardial hypertrophy associated with hypertension contains the - seed for further maladaptive development. Increased myocardial oxygen - consumption, impaired epicardial coronary perfusion, ventricular fibrosis and - remodelling, abnormalities in long-axis function and torsion, cause, to a varying - degree, a mixture of systolic and diastolic abnormalities. In addition, - chronotropic incompetence and peripheral factors such as lack of vasodilator - reserve and reduced arterial compliance further affect cardiac output - particularly on exercise. Many of these factors are common to hypertensive heart - failure with a normal ejection fraction as well as systolic heart failure. There - is increasing evidence that these apparently separate phenotypes are part of a - spectrum of heart failure differing only in the degree of ventricular remodelling - and volume changes. Furthermore, dichotomizing heart failure into systolic and - diastolic clinical entities has led to a paucity of clinical trials of therapies - for heart failure with a normal ejection fraction. Therapies aimed at reversing - myocardial fibrosis, and targets outside the heart such as enhancing vasodilator - reserve and improving chronotropic incompetence deserve further study and may - improve the exercise capacity of hypertensive heart failure patients. - Hypertension heart disease with heart failure is simply not a dysfunction of - systole and diastole. Other peripheral factors including heart rate and - vasodilator response with exercise may deserve equal attention in an attempt to - develop more effective treatments for this disorder. -FAU - Yip, G W -AU - Yip GW -AD - Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales - Hospital, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic - of China. -FAU - Fung, J W H -AU - Fung JW -FAU - Tan, Y-T -AU - Tan YT -FAU - Sanderson, J E -AU - Sanderson JE -LA - eng -PT - Journal Article -PT - Review -DEP - 20081127 -PL - England -TA - J Hum Hypertens -JT - Journal of human hypertension -JID - 8811625 -SB - IM -MH - Adaptation, Physiological -MH - Cardiomyopathy, Hypertrophic/diagnosis/epidemiology/physiopathology -MH - Comorbidity -MH - Diastole -MH - Disease Progression -MH - Echocardiography/methods -MH - Fibrosis/diagnosis/epidemiology/physiopathology -MH - Heart Failure/diagnosis/*epidemiology/*physiopathology -MH - Humans -MH - Hypertension/diagnosis/*epidemiology/*physiopathology -MH - Hypertrophy -MH - Hypertrophy, Left Ventricular/diagnosis/epidemiology/physiopathology -MH - Stroke Volume -MH - Systole -MH - Ventricular Dysfunction/diagnosis/epidemiology/physiopathology -MH - Ventricular Remodeling -RF - 125 -EDAT- 2008/11/28 09:00 -MHDA- 2009/06/11 09:00 -CRDT- 2008/11/28 09:00 -PHST- 2008/11/28 09:00 [pubmed] -PHST- 2009/06/11 09:00 [medline] -PHST- 2008/11/28 09:00 [entrez] -AID - jhh2008141 [pii] -AID - 10.1038/jhh.2008.141 [doi] -PST - ppublish -SO - J Hum Hypertens. 2009 May;23(5):295-306. doi: 10.1038/jhh.2008.141. Epub 2008 Nov - 27. - -PMID- 21184556 -OWN - NLM -STAT- MEDLINE -DCOM- 20110408 -LR - 20240718 -IS - 1932-8737 (Electronic) -IS - 0160-9289 (Print) -IS - 0160-9289 (Linking) -VI - 33 -IP - 12 -DP - 2010 Dec -TI - Cardio-oncology/onco-cardiology. -PG - 733-7 -LID - 10.1002/clc.20823 [doi] -AB - An understanding of onco-cardiology or cardio-oncology is critical for the - effective care of cancer patients. Virtually all antineoplastic agents are - associated with cardiotoxicity, which can be divided into 5 categories: direct - cytotoxic effects of chemotherapy and associated cardiac systolic dysfunction, - cardiac ischemia, arrhythmias, pericarditis, and chemotherapy-induced - repolarization abnormalities. Radiation therapy can also lead to coronary artery - disease and fibrotic changes to the valves, pericardium, and myocardium. All - patients being considered for chemotherapy, especially those who have prior - cardiac history, should undergo detailed cardiovascular evaluation to optimize - the treatment. Serial assessment of left ventricular systolic function and - cardiac biomarkers might also be considered in selected patient populations. - Cardiotoxic effects of chemotherapy might be decreased by the concurrent use of - angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, or - beta-blockers. Antiplatelet or anticoagulation therapy might be considered in - patients with a potential hypercoagulable state associated with chemotherapy or - cancer. Open dialogue between both cardiologists and oncologists will be required - for optimal patient care. -CI - Copyright © 2010 Wiley Periodicals, Inc. -FAU - Hong, Robert A -AU - Hong RA -AD - The Queen's Medical Center, Honolulu, Hawaii, USA. -FAU - Iimura, Takeshi -AU - Iimura T -FAU - Sumida, Kenneth N -AU - Sumida KN -FAU - Eager, Robert M -AU - Eager RM -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Cardiol -JT - Clinical cardiology -JID - 7903272 -RN - 0 (Anticoagulants) -RN - 0 (Antineoplastic Agents) -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Anticoagulants/therapeutic use -MH - Antineoplastic Agents/*adverse effects -MH - *Cardiology -MH - Cardiovascular Agents/therapeutic use -MH - Cooperative Behavior -MH - Heart Diseases/chemically induced/diagnosis/*etiology/prevention & control -MH - Heart Function Tests -MH - Humans -MH - *Medical Oncology -MH - *Patient Care Team -MH - Predictive Value of Tests -MH - Radiation Injuries/diagnosis/*etiology/prevention & control -MH - Thrombophilia/*chemically induced/diagnosis/prevention & control -PMC - PMC6653579 -EDAT- 2010/12/25 06:00 -MHDA- 2011/04/09 06:00 -PMCR- 2010/12/23 -CRDT- 2010/12/25 06:00 -PHST- 2010/12/25 06:00 [entrez] -PHST- 2010/12/25 06:00 [pubmed] -PHST- 2011/04/09 06:00 [medline] -PHST- 2010/12/23 00:00 [pmc-release] -AID - CLC20823 [pii] -AID - 10.1002/clc.20823 [doi] -PST - ppublish -SO - Clin Cardiol. 2010 Dec;33(12):733-7. doi: 10.1002/clc.20823. - -PMID- 16978992 -OWN - NLM -STAT- MEDLINE -DCOM- 20061017 -LR - 20071115 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 48 -IP - 6 -DP - 2006 Sep 19 -TI - Erectile dysfunction in heart failure patients. -PG - 1111-9 -AB - Chronic heart failure (HF) and erectile dysfunction (ED) are 2 highly prevalent - disorders that frequently occur concomitantly. Coronary artery disease, HF, and - ED share several common risk factors, including diabetes mellitus, hypertension, - smoking, and dyslipidemia. Additionally, the distinct physiologic sequelae of HF - create unique organic and psychologic factors contributing to ED in this patient - population. Standard HF therapy with beta-receptor blockers, digoxin and thiazide - diuretics may worsen sexual dysfunction owing to medication side effects. This - may, in turn, lead to noncompliance in misguided efforts to retain satisfactory - sexual activity, with secondary worsening of cardiac capacity. This review - describes the unique aspects of ED in the HF population. -FAU - Schwarz, Ernst R -AU - Schwarz ER -AD - Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, Los - Angeles, California 90048, USA. ernst.schwarz@cshs.org -FAU - Rastogi, Saurabh -AU - Rastogi S -FAU - Kapur, Vishal -AU - Kapur V -FAU - Sulemanjee, Nasir -AU - Sulemanjee N -FAU - Rodriguez, Jennifer J -AU - Rodriguez JJ -LA - eng -PT - Journal Article -PT - Review -DEP - 20060828 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Cardiac Output, Low/*complications/drug therapy/physiopathology -MH - Depression/etiology/therapy -MH - Erectile Dysfunction/drug therapy/*etiology/physiopathology/psychology -MH - Humans -MH - Male -MH - Sex Counseling -RF - 123 -EDAT- 2006/09/19 09:00 -MHDA- 2006/10/18 09:00 -CRDT- 2006/09/19 09:00 -PHST- 2006/03/21 00:00 [received] -PHST- 2006/04/26 00:00 [revised] -PHST- 2006/05/01 00:00 [accepted] -PHST- 2006/09/19 09:00 [pubmed] -PHST- 2006/10/18 09:00 [medline] -PHST- 2006/09/19 09:00 [entrez] -AID - S0735-1097(06)01730-X [pii] -AID - 10.1016/j.jacc.2006.05.052 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2006 Sep 19;48(6):1111-9. doi: 10.1016/j.jacc.2006.05.052. - Epub 2006 Aug 28. - -PMID- 22204143 -OWN - NLM -STAT- MEDLINE -DCOM- 20120301 -LR - 20111229 -IS - 0012-7183 (Print) -IS - 0012-7183 (Linking) -VI - 127 -IP - 21 -DP - 2011 -TI - [Out-of-hospital cardiac arrest]. -PG - 2287-93 -AB - Cardiac arrest as the first symptom of coronary artery disease is not uncommon. - Some of previously healthy people with sudden cardiac arrest may be saved by - effective resuscitation and post-resuscitative therapy. The majority of cardiac - arrest patients experience the cardiac arrest outside of the hospital, in which - case early recognition of lifelessness, commencement of basic life support and - entry to professional care without delay are the prerequisites for recovery. - After the heart has started beating again, the clinical picture of - post-resuscitation syndrome must be recognized and appropriate treatment - utilized. -FAU - Virkkunen, Ilkka -AU - Virkkunen I -AD - TAYS, ensihoitokeskus. -FAU - Hoppu, Sanna -AU - Hoppu S -FAU - Kämäräinen, Antti -AU - Kämäräinen A -LA - fin -PT - English Abstract -PT - Journal Article -PT - Review -TT - Sydämenpysähdys sairaalan ulkopuolella. -PL - Finland -TA - Duodecim -JT - Duodecim; laaketieteellinen aikakauskirja -JID - 0373207 -SB - IM -MH - Cardiopulmonary Resuscitation/*methods -MH - Death, Sudden, Cardiac/*prevention & control -MH - Emergency Medical Services/*organization & administration -MH - Humans -MH - Out-of-Hospital Cardiac Arrest/*diagnosis/*therapy -EDAT- 2011/12/30 06:00 -MHDA- 2012/03/02 06:00 -CRDT- 2011/12/30 06:00 -PHST- 2011/12/30 06:00 [entrez] -PHST- 2011/12/30 06:00 [pubmed] -PHST- 2012/03/02 06:00 [medline] -PST - ppublish -SO - Duodecim. 2011;127(21):2287-93. - -PMID- 21529993 -OWN - NLM -STAT- MEDLINE -DCOM- 20120727 -LR - 20220309 -IS - 1878-3279 (Electronic) -IS - 0171-2985 (Linking) -VI - 217 -IP - 5 -DP - 2012 May -TI - CD40 ligand: a neo-inflammatory molecule in vascular diseases. -PG - 521-32 -LID - 10.1016/j.imbio.2011.03.010 [doi] -AB - CD40 Ligand (CD40L), a member of the TNF family, was initially thought to be - solely implicated in thymus-dependent humoral responses. However, work by several - groups showed that CD40L plays a more global role in various systems. Recent - evidence has outlined an important role for CD40L in the physiopathology of the - vascular system. Indeed, by interacting with its principal receptor, CD40, or - with the recently identified receptors, namely αIIbβ3, α5β1, and Mac-1 integrins, - CD40L displayed many biological functions in different types of vascular cells. - In addition, the CD40L system was demonstrated a major player in the pathology of - vascular diseases, such as atherosclerosis and restenosis. This review outlines - the expression pattern and the functional properties of CD40L and its receptors - at different cellular levels in the vascular system. In addition, we thoroughly - describe evidence showing the implication of CD40L interactions in - atherosclerosis, restenosis, and their associated clinical complications. -CI - Copyright © 2011 Elsevier GmbH. All rights reserved. -FAU - Hassan, Ghada S -AU - Hassan GS -AD - Laboratoire d'Immunologie Cellulaire et Moléculaire, Centre Hospitalier de - l'Université de Montréal, Hôpital Saint-Luc, Montréal QC H2X 1P1, Canada. -FAU - Merhi, Yahye -AU - Merhi Y -FAU - Mourad, Walid -AU - Mourad W -LA - eng -GR - Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110407 -PL - Netherlands -TA - Immunobiology -JT - Immunobiology -JID - 8002742 -RN - 0 (CD40 Antigens) -RN - 147205-72-9 (CD40 Ligand) -SB - IM -MH - Animals -MH - CD40 Antigens/immunology -MH - CD40 Ligand/*immunology -MH - Coronary Restenosis/immunology -MH - Humans -MH - Inflammation/immunology -MH - Vascular Diseases/*immunology -EDAT- 2011/05/03 06:00 -MHDA- 2012/07/28 06:00 -CRDT- 2011/05/03 06:00 -PHST- 2011/03/24 00:00 [received] -PHST- 2011/03/29 00:00 [accepted] -PHST- 2011/05/03 06:00 [entrez] -PHST- 2011/05/03 06:00 [pubmed] -PHST- 2012/07/28 06:00 [medline] -AID - S0171-2985(11)00068-4 [pii] -AID - 10.1016/j.imbio.2011.03.010 [doi] -PST - ppublish -SO - Immunobiology. 2012 May;217(5):521-32. doi: 10.1016/j.imbio.2011.03.010. Epub - 2011 Apr 7. - -PMID- 17992310 -OWN - NLM -STAT- MEDLINE -DCOM- 20080602 -LR - 20190608 -VI - 22 -IP - 1 -DP - 2007 Jan-Mar -TI - Aspirin resistance and atherothrombosis. -PG - 96-103 -FAU - Gabriel, Sthefano Atique -AU - Gabriel SA -AD - Pontifícia Universidade Católica de São Paulo - Campus Sorocaba. - sthefanogabriel@yahoo.com.br -FAU - Beteli, Camila Baumann -AU - Beteli CB -FAU - Tanighuchi, Rodrigo Seiji -AU - Tanighuchi RS -FAU - Tristão, Cristiane Knopp -AU - Tristão CK -FAU - Gabriel, Edmo Atique -AU - Gabriel EA -FAU - Job, José Roberto Pretel Pereira -AU - Job JR -LA - eng -LA - por -PT - Journal Article -PT - Review -PL - Brazil -TA - Rev Bras Cir Cardiovasc -JT - Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade - Brasileira de Cirurgia Cardiovascular -JID - 9104279 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 31C4KY9ESH (Nitric Oxide) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Analysis of Variance -MH - Aspirin/*pharmacology/therapeutic use -MH - Atherosclerosis/*prevention & control -MH - Coronary Thrombosis/*prevention & control -MH - *Drug Resistance/physiology -MH - Humans -MH - Immunohistochemistry -MH - Nitric Oxide/metabolism -MH - Platelet Aggregation/*drug effects -MH - Platelet Aggregation Inhibitors/*pharmacology/therapeutic use -RF - 37 -EDAT- 2007/11/10 09:00 -MHDA- 2008/06/03 09:00 -CRDT- 2007/11/10 09:00 -PHST- 2007/11/10 09:00 [pubmed] -PHST- 2008/06/03 09:00 [medline] -PHST- 2007/11/10 09:00 [entrez] -AID - S0102-76382007000100017 [pii] -AID - 10.1590/s0102-76382007000100017 [doi] -PST - ppublish -SO - Rev Bras Cir Cardiovasc. 2007 Jan-Mar;22(1):96-103. doi: - 10.1590/s0102-76382007000100017. - -PMID- 22159451 -OWN - NLM -STAT- MEDLINE -DCOM- 20121116 -LR - 20250214 -IS - 1432-1440 (Electronic) -IS - 0946-2716 (Linking) -VI - 90 -IP - 8 -DP - 2012 Aug -TI - Circulating microRNAs: novel biomarkers for cardiovascular diseases. -PG - 865-75 -LID - 10.1007/s00109-011-0840-5 [doi] -AB - MicroRNAs (miRNAs) are a novel class of small, non-coding, single-stranded RNAs - that negatively regulate gene expression via translational inhibition or mRNA - degradation followed by protein synthesis repression. Many miRNAs are expressed - in a tissue- and/or cell-specific manner and their expression patterns are - reflective of underlying patho-physiologic processes. miRNAs can be detected in - serum or in plasma in a remarkably stable form, making them attractive biomarkers - for human diseases. This review describes the progress of identifying circulating - miRNAs as novel biomarkers for diverse cardiovascular diseases, including acute - myocardial infarction, heart failure, coronary artery disease, diabetes, stroke, - essential hypertension, and acute pulmonary embolism. In addition, the origin and - function and the different strategies to identify circulating miRNAs as novel - biomarkers for cardiovascular diseases are also discussed. Rarely has an - opportunity arisen to advance such new biology for the diagnosis of cardiac - diseases. -FAU - Xu, Jiahong -AU - Xu J -AD - Department of Cardiology, Tongji Hospital, Tongji University School of Medicine, - 200065, Shanghai, China. -FAU - Zhao, Jiangmin -AU - Zhao J -FAU - Evan, Graham -AU - Evan G -FAU - Xiao, Chunyang -AU - Xiao C -FAU - Cheng, Yan -AU - Cheng Y -FAU - Xiao, Junjie -AU - Xiao J -LA - eng -PT - Journal Article -PT - Review -DEP - 20111208 -PL - Germany -TA - J Mol Med (Berl) -JT - Journal of molecular medicine (Berlin, Germany) -JID - 9504370 -RN - 0 (Biomarkers) -RN - 0 (MicroRNAs) -SB - IM -MH - Animals -MH - Biomarkers/*blood -MH - Cardiovascular Diseases/*blood -MH - Humans -MH - MicroRNAs/*blood -EDAT- 2011/12/14 06:00 -MHDA- 2012/12/10 06:00 -CRDT- 2011/12/14 06:00 -PHST- 2011/09/09 00:00 [received] -PHST- 2011/11/28 00:00 [accepted] -PHST- 2011/11/26 00:00 [revised] -PHST- 2011/12/14 06:00 [entrez] -PHST- 2011/12/14 06:00 [pubmed] -PHST- 2012/12/10 06:00 [medline] -AID - 10.1007/s00109-011-0840-5 [doi] -PST - ppublish -SO - J Mol Med (Berl). 2012 Aug;90(8):865-75. doi: 10.1007/s00109-011-0840-5. Epub - 2011 Dec 8. - -PMID- 17064207 -OWN - NLM -STAT- MEDLINE -DCOM- 20070110 -LR - 20131121 -IS - 0277-0008 (Print) -IS - 0277-0008 (Linking) -VI - 26 -IP - 11 -DP - 2006 Nov -TI - Management of antiplatelet therapy for minimization of bleeding risk before - cardiac surgery. -PG - 1616-25 -AB - Antiplatelet therapy is commonly administered for primary and secondary - prevention of stroke, recurrent angina, myocardial infarction, and death in - patients with cardiovascular disorders. It also is associated with an increased - risk of bleeding. We describe the management of antiplatelet therapy in patients - undergoing coronary artery bypass graft surgery. In addition, we provide basic - information about the mechanisms of action by which the most common antiplatelet - agents inhibit platelet function. This information is integrated with results - from pharmacologic studies and clinical trials. Determining the net effect in - patients undergoing coronary artery bypass graft surgery requires knowledge about - the pharmacokinetics, pharmacodynamics, and clinical efficacy of each drug, and - an estimation of the absolute thrombotic versus hemorrhagic risk for each - patient. -FAU - Weant, Kyle A -AU - Weant KA -AD - University of North Carolina Hospitals and the School of Pharmacy, University of - North Carolina, Chapel Hill, North Carolina, USA. -FAU - Flynn, Jeremy F -AU - Flynn JF -FAU - Akers, Wendell S -AU - Akers WS -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Pharmacotherapy -JT - Pharmacotherapy -JID - 8111305 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Platelet Glycoprotein GPIIb-IIIa Complex) -RN - 61D2G4IYVH (Adenosine Diphosphate) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Adenosine Diphosphate/antagonists & inhibitors -MH - Aspirin/therapeutic use -MH - Blood Loss, Surgical/*prevention & control -MH - *Coronary Artery Bypass -MH - Coronary Thrombosis/prevention & control -MH - Humans -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors -RF - 80 -EDAT- 2006/10/27 09:00 -MHDA- 2007/01/11 09:00 -CRDT- 2006/10/27 09:00 -PHST- 2006/10/27 09:00 [pubmed] -PHST- 2007/01/11 09:00 [medline] -PHST- 2006/10/27 09:00 [entrez] -AID - 10.1592/phco.26.11.1616 [doi] -PST - ppublish -SO - Pharmacotherapy. 2006 Nov;26(11):1616-25. doi: 10.1592/phco.26.11.1616. - -PMID- 18762688 -OWN - NLM -STAT- MEDLINE -DCOM- 20090325 -LR - 20101118 -IS - 1557-2501 (Electronic) -IS - 1042-3931 (Linking) -VI - 20 -IP - 9 -DP - 2008 Sep -TI - Dissection of the right coronary ostium and sinus of Valsalva during right - coronary artery angioplasty. -PG - E277-80 -AB - We describe a case of dissection of the coronary ostium and sinus of Valsalva - during a recanalization procedure to address chronic total occlusion of the right - coronary artery (RCA). The patient was treated conservatively, and 1 month later, - underwent angioplasty of the RCA and marginal branch. Based on a review of the - incidence of, management strategies for, and causes of dissection of the RCA and - ascending aorta, we conclude that the frequency of this condition may be - underestimated and, in view of the increasing number of elderly patients, will - rise over time. -FAU - Bryniarski, Leszek -AU - Bryniarski L -AD - Department of Cardiology and Hypertension, Institute of Cardiology, Jagiellonian - University Medical College, Cracow, Poland. l_bryniarski@poczta.fm -FAU - Dragan, Jacek -AU - Dragan J -FAU - Dudek, Dariusz -AU - Dudek D -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - J Invasive Cardiol -JT - The Journal of invasive cardiology -JID - 8917477 -SB - IM -MH - Aged -MH - Angiography -MH - Angioplasty, Balloon, Coronary/*adverse effects -MH - Carotid Artery, Internal, Dissection/*diagnosis/*etiology -MH - Coronary Angiography -MH - Coronary Stenosis/therapy -MH - Coronary Vessels/*injuries -MH - Humans -MH - Male -MH - Sinus of Valsalva/*injuries -RF - 21 -EDAT- 2008/09/03 09:00 -MHDA- 2009/03/26 09:00 -CRDT- 2008/09/03 09:00 -PHST- 2008/09/03 09:00 [pubmed] -PHST- 2009/03/26 09:00 [medline] -PHST- 2008/09/03 09:00 [entrez] -PST - ppublish -SO - J Invasive Cardiol. 2008 Sep;20(9):E277-80. - -PMID- 18460708 -OWN - NLM -STAT- MEDLINE -DCOM- 20080715 -LR - 20080507 -IS - 1557-2501 (Electronic) -IS - 1042-3931 (Linking) -VI - 20 -IP - 5 -DP - 2008 May -TI - Pharmacological and mechanical revascularization strategies in STEMI: integration - of the two approaches. -PG - 231-8 -AB - The main goal of treatment for ST-segment elevation myocardial infarction (STEMI) - is prompt and complete reperfusion of the infarcted myocardium. This may be - achieved using either fibrinolytic agents or primary percutaneous coronary - intervention (PPCI, involving angioplasty with or without coronary artery - stenting). In the clinical trial setting, PPCI appears to yield superior results. - However, this treatment option is frequently either unavailable or associated - with unacceptably long delays between symptom onset and reperfusion. In contrast, - fibrinolytic therapy is almost universally available and, in the absence of - contraindications, can even be initiated before hospital arrival. The success of - fibrinolytic treatment is likely to improve as advanced pharmacological regimens - are explored. For example, one of the main disadvantages of standard fibrinolytic - therapy is that, paradoxically, it increases thrombin production and platelet - aggregation. There is thus a rationale for combining fibrinolysis with aggressive - antiplatelet therapy. The use of aspirin is now universal in fibrinolytic-treated - patients, and the use of a thienopyridine (such as clopidogrel) appears to be - beneficial, but additional antiplatelet inhibition using a platelet glycoprotein - IIb/IIIa inhibitor (such as abciximab or eptifibatide) is controversial. - Adjunctive use of antithrombotic therapy is also beneficial during fibrinolytic - treatment. This review outlines the growing list of treatment options available - for these high-risk patients and highlights the advantages of some of the newer - pharmacological strategies. -FAU - Pollack, Charles Jr -AU - Pollack C Jr -AD - Pennsylvania Hospital, Department of Emergency Medicine, University of - Pennsylvania School of Medicine, 800 Spruce Street, Philadelphia, PA, 19107, USA. - pollackc@pahosp.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Invasive Cardiol -JT - The Journal of invasive cardiology -JID - 8917477 -RN - 0 (Fibrinolytic Agents) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Angioplasty/*methods -MH - Combined Modality Therapy -MH - Coronary Thrombosis/*prevention & control -MH - Fibrinolytic Agents/*therapeutic use -MH - Humans -MH - Myocardial Infarction/drug therapy/surgery/*therapy -MH - Myocardial Reperfusion/methods -MH - Myocardial Revascularization/*methods -MH - Platelet Aggregation Inhibitors/*therapeutic use -RF - 69 -EDAT- 2008/05/08 09:00 -MHDA- 2008/07/17 09:00 -CRDT- 2008/05/08 09:00 -PHST- 2008/05/08 09:00 [pubmed] -PHST- 2008/07/17 09:00 [medline] -PHST- 2008/05/08 09:00 [entrez] -PST - ppublish -SO - J Invasive Cardiol. 2008 May;20(5):231-8. - -PMID- 18428018 -OWN - NLM -STAT- MEDLINE -DCOM- 20080617 -LR - 20161124 -IS - 1365-2060 (Electronic) -IS - 0785-3890 (Linking) -VI - 40 -IP - 4 -DP - 2008 -TI - Drug-eluting stents - what should be improved? -PG - 242-52 -LID - 10.1080/07853890801964948 [doi] -AB - Despite the success of drug-eluting stents (DES) in reducing restenosis and the - need for target vessel revascularization, several deficiencies have been - unraveled since their first clinical application including the risk of stent - thrombosis, undesired effects due to the stent polymer as well as the stent - itself, and incomplete inhibition of restenosis (especially in complex lesions). - Several novel stent systems are being investigated in order to address these - issues. In second-generation DES, the rapamycin analogues zotarolimus and - everolimus (and more recently biolimus) have been most extensively studied. - Furthermore, special stent-coatings to actively promote endothelial healing (in - order to reduce the risk of stent thrombosis) and to further reduce restenosis - have been employed. To avoid undesirable effects of currently applied (durable) - polymers, biocompatible and bioabsorbable polymers as well as DES delivery - systems without the need for a polymer have been developed. Bioabsorbable stents, - both polymeric and metallic, were developed to decrease potential late - complications after stent implantation. Although most of these innovative novel - principles intuitively seem appealing and demonstrate good results in initial - clinical evaluations, long-term large-scale studies are necessary in order to - reliably assess whether these novel systems are truly superior to - first-generation DES with respect to safety and efficacy. -FAU - Steffel, Jan -AU - Steffel J -AD - Cardiology, University Hospital Zürich, Switzerland. j.steffel@gmx.ch -FAU - Eberli, Franz R -AU - Eberli FR -FAU - Lüscher, Thomas F -AU - Lüscher TF -FAU - Tanner, Felix C -AU - Tanner FC -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Ann Med -JT - Annals of medicine -JID - 8906388 -RN - 0 (Coated Materials, Biocompatible) -RN - 0 (Polymers) -RN - 9HW64Q8G6G (Everolimus) -RN - U36PGF65JH (umirolimus) -RN - W36ZG6FT64 (Sirolimus) -SB - IM -MH - *Coated Materials, Biocompatible -MH - Coronary Restenosis/*prevention & control -MH - Coronary Vessels/drug effects/pathology -MH - Drug Delivery Systems -MH - Drug-Eluting Stents/*adverse effects -MH - Everolimus -MH - Humans -MH - Polymers/adverse effects/chemistry -MH - Sirolimus/administration & dosage/analogs & derivatives -MH - Thrombosis/etiology/prevention & control -RF - 58 -EDAT- 2008/04/23 09:00 -MHDA- 2008/06/18 09:00 -CRDT- 2008/04/23 09:00 -PHST- 2008/04/23 09:00 [pubmed] -PHST- 2008/06/18 09:00 [medline] -PHST- 2008/04/23 09:00 [entrez] -AID - 791968158 [pii] -AID - 10.1080/07853890801964948 [doi] -PST - ppublish -SO - Ann Med. 2008;40(4):242-52. doi: 10.1080/07853890801964948. - -PMID- 18183779 -OWN - NLM -STAT- MEDLINE -DCOM- 20080215 -LR - 20161124 -IS - 0556-6177 (Print) -IS - 0556-6177 (Linking) -VI - 51 -IP - 3 -DP - 2007 Jul-Sep -TI - [Dual-source CT coronary angiography]. -PG - 4-8 -AB - Multidetector computed tomography (MDCT) has been demonstrated to be a very - useful technique to non-invasively study coronary arteries. Despite the high - spatial and temporal resolution of 64-slice MDCT scanners, this technique has - several limitations. Dual-source computed tomography (DSCT) allows to study - coronary arteries with excellent diagnostic quality in all subjects independent - of the heart rate, thus avoiding the use of beta-blockers. In this article DSCT - studies from three subjects with elevated heart rate and irregular heart rhythm - are described. Usefulness of this technique to obtain studies of excellent - quality in cases in which conventional 64-row-MDCT might present limitations is - emphasized. -FAU - Bastarrika, G -AU - Bastarrika G -AD - Servicio de Radiología, Clínica Universitaria, Facultad de Medicina, Universidad - de Navarra, Pamplona. bastarrika@unav.es -FAU - Arraiza, M -AU - Arraiza M -FAU - Pueyo, J -AU - Pueyo J -LA - spa -PT - Case Reports -PT - Journal Article -PT - Review -TT - Coronariografía por tomografía computarizada de doble fuente. -PL - Spain -TA - Rev Med Univ Navarra -JT - Revista de medicina de la Universidad de Navarra -JID - 0123071 -SB - IM -MH - Adult -MH - Aged -MH - Chest Pain/diagnosis -MH - Coronary Angiography/instrumentation/*methods -MH - Coronary Restenosis/diagnostic imaging -MH - Equipment Design -MH - Heart Rate -MH - Humans -MH - Male -MH - Middle Aged -MH - Postoperative Complications/diagnostic imaging -MH - Tachycardia/diagnostic imaging -MH - Tomography, Spiral Computed/instrumentation/*methods -RF - 22 -EDAT- 2008/01/11 09:00 -MHDA- 2008/02/19 09:00 -CRDT- 2008/01/11 09:00 -PHST- 2008/01/11 09:00 [pubmed] -PHST- 2008/02/19 09:00 [medline] -PHST- 2008/01/11 09:00 [entrez] -PST - ppublish -SO - Rev Med Univ Navarra. 2007 Jul-Sep;51(3):4-8. - -PMID- 22112919 -OWN - NLM -STAT- MEDLINE -DCOM- 20120702 -LR - 20220318 -IS - 1873-2380 (Electronic) -IS - 0021-9290 (Linking) -VI - 45 -IP - 1 -DP - 2012 Jan 3 -TI - Mechanotransduction in adipocytes. -PG - 1-8 -LID - 10.1016/j.jbiomech.2011.10.023 [doi] -AB - Obesity is widely recognized as a major public health problem due to its strong - association with a number of serious chronic diseases including hyperlipidemia, - hypertension, type II diabetes and coronary atherosclerotic heart disease. During - the development of obesity, the positive energy balance involves recruitment of - new adipocytes from preadipocytes in adipose tissue, which have proliferated and - differentiated. Given that cells in adipose tissues are physiologically exposed - to compound mechanical loading: tensile, compressive and shear strains/stresses, - which are caused by bodyweight loads as well as by weight-bearing, it is - important to determine whether the adipose conversion process is influenced by - mechanical stimulations. In this article we provide a comprehensive review of the - experimental studies addressing mechanotransduction in adipocytes, as well as of - mathematical and computational models that are useful for studying - mechanotransduction in adipocytes or for quantifying the responsiveness of - adipocytes to different types of mechanical loading. The new understanding that - adipogenesis is influenced by mechanical stimulations has the potential to open - new and important research paths, driven by mechanotransduction, to explore - mechanisms as well as treatment approaches in obesity and related conditions. -CI - Copyright © 2011 Elsevier Ltd. All rights reserved. -FAU - Shoham, Naama -AU - Shoham N -AD - Department of Biomedical Engineering, Tel Aviv University, Tel Aviv 69978, - Israel. -FAU - Gefen, Amit -AU - Gefen A -LA - eng -PT - Journal Article -PT - Review -DEP - 20111121 -PL - United States -TA - J Biomech -JT - Journal of biomechanics -JID - 0157375 -SB - IM -MH - Adipocytes/*pathology/*physiology -MH - Animals -MH - Humans -MH - Mechanotransduction, Cellular/*physiology -MH - Obesity/*pathology -MH - Stress, Mechanical -EDAT- 2011/11/25 06:00 -MHDA- 2012/07/03 06:00 -CRDT- 2011/11/25 06:00 -PHST- 2011/08/12 00:00 [received] -PHST- 2011/10/01 00:00 [revised] -PHST- 2011/10/04 00:00 [accepted] -PHST- 2011/11/25 06:00 [entrez] -PHST- 2011/11/25 06:00 [pubmed] -PHST- 2012/07/03 06:00 [medline] -AID - S0021-9290(11)00662-2 [pii] -AID - 10.1016/j.jbiomech.2011.10.023 [doi] -PST - ppublish -SO - J Biomech. 2012 Jan 3;45(1):1-8. doi: 10.1016/j.jbiomech.2011.10.023. Epub 2011 - Nov 21. - -PMID- 16682381 -OWN - NLM -STAT- MEDLINE -DCOM- 20070108 -LR - 20181201 -IS - 0195-668X (Print) -IS - 0195-668X (Linking) -VI - 27 -IP - 16 -DP - 2006 Aug -TI - Evidence-based use of levosimendan in different clinical settings. -PG - 1908-20 -AB - Levosimendan is a new calcium sensitizer and K-ATP channel opener. Compared with - other inodilators, it improves myocardial contractility without increasing oxygen - requirements and induces peripheral and coronary vasodilation with a potential - anti-stunning, anti-ischaemic effect. The documentation regarding levosimendan is - one of the largest ever on the safety and efficacy of a new pharmacological agent - in acute heart failure syndromes. Recent experiences in small-scale studies and - randomized clinical trials have led to greater interest in the use of this drug - for the support of impaired cardiac function also in patients with ischaemic - heart disease and cardiogenic or septic shock. It is also demonstrated that this - drug could be used as bridge therapy for the peri-operative phase of cardiac - surgery in both adult and paediatric populations. This review summarizes the - evidence from published scientific literature regarding the use of levosimendan - in various clinical settings. -FAU - De Luca, Leonardo -AU - De Luca L -AD - Division of Cardiology, European Hospital, Rome, Italy. -FAU - Colucci, Wilson S -AU - Colucci WS -FAU - Nieminen, Markku S -AU - Nieminen MS -FAU - Massie, Barry M -AU - Massie BM -FAU - Gheorghiade, Mihai -AU - Gheorghiade M -LA - eng -PT - Journal Article -PT - Review -DEP - 20060427 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (Cardiotonic Agents) -RN - 0 (Hydrazones) -RN - 0 (Pyridazines) -RN - 349552KRHK (Simendan) -SB - IM -CIN - Eur Heart J. 2007 Feb;28(4):515. doi: 10.1093/eurheartj/ehl487. PMID: 17283001 -MH - Administration, Oral -MH - Adult -MH - Arrhythmias, Cardiac/chemically induced -MH - Cardiotonic Agents/pharmacology/*therapeutic use -MH - Child -MH - Heart Failure/*drug therapy -MH - Humans -MH - Hydrazones/pharmacology/*therapeutic use -MH - Intraoperative Care -MH - Myocardial Ischemia/*drug therapy -MH - Pyridazines/pharmacology/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Shock, Cardiogenic/*drug therapy -MH - Simendan -RF - 96 -EDAT- 2006/05/10 09:00 -MHDA- 2007/01/09 09:00 -CRDT- 2006/05/10 09:00 -PHST- 2006/05/10 09:00 [pubmed] -PHST- 2007/01/09 09:00 [medline] -PHST- 2006/05/10 09:00 [entrez] -AID - ehi875 [pii] -AID - 10.1093/eurheartj/ehi875 [doi] -PST - ppublish -SO - Eur Heart J. 2006 Aug;27(16):1908-20. doi: 10.1093/eurheartj/ehi875. Epub 2006 - Apr 27. - -PMID- 17019400 -OWN - NLM -STAT- MEDLINE -DCOM- 20070329 -LR - 20101118 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 54 -IP - 5 -DP - 2006 Oct -TI - PCI versus CABG versus medical therapy in 2006. -PG - 643-72 -AB - The decision to offer patients with myocardial ischemia a coronary artery bypass - graft (CABG) surgery has been largely determined by extent of coronary artery - disease (CAD) and left ventricular function, since the early 1970's. Based upon - subset analyses, and long-term follow-up, of three moderate-sized trials of - stable patients and two small trials of unstable angina (excluding recent - myocardial infarction, MI) patients, the notion has persisted that patients with - left main narrowing >50% or three-vessel stenoses >70%, or even two-vessel - stenoses >70%, where one of the vessels is the proximal left anterior descending, - derive a "survival benefit" relative to medical therapy (MED), from CABG - (anatomic paradigm). The MED of the original CABG versus MED trials consisted of - little more than anti-anginal medications, used on an as-needed basis. In the - ensuing 3 decades, multiple large, well done, randomized clinical trials have - established a survival benefit for 4 different forms of MED among a broad - spectrum of CAD patients. Aspirin; lipid lowering, especially with statins; - b-blockers; and angiotensin-converting-enzyme inhibitors and/or angiotensin - receptor blocking agents; have all been shown to enhance survival, as well as - reduce other objective adverse outcomes of CAD. The advances in MED, coupled with - the small but significant mortality and morbidities of both CABG and percutaneous - coronary intervention (PCI), are among the reasons to skeptically consider - potential "survival benefit" of revascularization. A more common and far more - easily justified reason to consider revascularization is to relieve "medically - refractory" myocardial ischemia, particularly when the ischemia is accompanied by - symptoms. Accordingly, documentation of medically refractory myocardial ischemia - provides the answer to the first question of myocardial revascularization, "Is - this patient likely to derive clinical benefit from revascularization, at this - time?" It is only after this question has been answered that one needs to - consider the relative advantages and disadvantages of PCI versus CABG - (physiologic paradigm). Two of the relative advantages of PCI, namely speed of - reperfusion, and relatively low morbidity, are among the reasons that most - randomized trial data, and most clinical application of revascularization to - patients with MI (ST-elevation MI [STEMI], and non-STEMI) have been by PCI. In - contrast, for stable patients with medically refractory ischemia, anatomic - considerations continue to be relevant to the choice between CABG and PCI. - Specific advantages of CABG include: its potential to revascularize chronically - occluded vessels with collaterals supplying viable myocardium; the fact that - conduits protect territories rather than simply treating lesions; and the greater - durability of conduits compared to bare-metal stents (drug-eluting stents may - change the picture). Based on these principles, physiologic, rather than - anatomic, considerations are most useful in determining whether to revascularize, - and how urgently to revascularize (STEMI is an emergent indication and high-risk - non-STEMI an urgent indication). Coronary anatomy, including both number of - vessels and lesion characteristics, continues to help decide between CABG and - PCI, and in formulating patient specific strategies. -FAU - Morrison, D -AU - Morrison D -AD - Yakima Heart Center, 406 S. 30th Avenue, Yakima, WA 98902, USA. - dr.morrison@yakimaheartcenter.com -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -SB - IM -MH - *Angioplasty, Balloon, Coronary -MH - *Coronary Artery Bypass -MH - Humans -MH - Myocardial Ischemia/*therapy -RF - 367 -EDAT- 2006/10/05 09:00 -MHDA- 2007/03/30 09:00 -CRDT- 2006/10/05 09:00 -PHST- 2006/10/05 09:00 [pubmed] -PHST- 2007/03/30 09:00 [medline] -PHST- 2006/10/05 09:00 [entrez] -PST - ppublish -SO - Minerva Cardioangiol. 2006 Oct;54(5):643-72. - -PMID- 18262841 -OWN - NLM -STAT- MEDLINE -DCOM- 20080728 -LR - 20141120 -IS - 1444-2892 (Electronic) -IS - 1443-9506 (Linking) -VI - 17 -IP - 3 -DP - 2008 Jun -TI - The new world of cardiac interventions: a brief review of the recent advances in - non-coronary percutaneous interventions. -PG - 186-99 -LID - 10.1016/j.hlc.2007.10.019 [doi] -AB - Advances in cardiovascular interventional techniques have allowed percutaneous - treatment of conditions that either previously required open operations or have - not been amenable to treatment. Conditions such as atrial and ventricular septal - defects and patent foramen ovale are now amenable to percutaneous closure using - implantable devices. A number of strategies have evolved to reduce the risk of - stroke such as percutaneous occlusion of the left atrial appendage for patients - in atrial fibrillation. Valvular heart disease and complications of its repair - are approachable via the percutaneous route. Percutaneous pulmonary and aortic - valve replacements have been performed in humans. There are evolving techniques - for repair of the mitral valve and of prosthetic paravalvular leaks using devices - such as the Amplatzer septal occluder to repair the defects without the need for - repeat open heart surgery. Hypertrophic cardiomyopathy with left ventricular - outflow tract obstruction can now be approached using alcohol septal ablation - with results comparable to the surgical technique. These advances have occurred - as a result of improvement in the design of the devices used as well as a better - understanding of the pathophysiology of conditions. Many of these techniques are - in evolution and in this paper we review some of the recent developments in this - dynamic area of interventional cardiology. -FAU - Garg, Pallav -AU - Garg P -AD - Department of Cardiology, Alfred Hospital, Commercial Road, Prahran, Victoria - 3004, Australia. -FAU - Walton, Antony S -AU - Walton AS -LA - eng -PT - Journal Article -PT - Review -DEP - 20080211 -PL - Australia -TA - Heart Lung Circ -JT - Heart, lung & circulation -JID - 100963739 -SB - IM -MH - Cardiac Catheterization/methods -MH - Cardiovascular Surgical Procedures/*methods -MH - Heart Septal Defects/surgery -MH - Heart Valve Diseases/surgery -MH - Heart Valve Prosthesis Implantation/methods -MH - Humans -MH - Minimally Invasive Surgical Procedures/*methods -RF - 86 -EDAT- 2008/02/12 09:00 -MHDA- 2008/07/29 09:00 -CRDT- 2008/02/12 09:00 -PHST- 2007/06/24 00:00 [received] -PHST- 2007/10/24 00:00 [revised] -PHST- 2007/10/29 00:00 [accepted] -PHST- 2008/02/12 09:00 [pubmed] -PHST- 2008/07/29 09:00 [medline] -PHST- 2008/02/12 09:00 [entrez] -AID - S1443-9506(07)01067-0 [pii] -AID - 10.1016/j.hlc.2007.10.019 [doi] -PST - ppublish -SO - Heart Lung Circ. 2008 Jun;17(3):186-99. doi: 10.1016/j.hlc.2007.10.019. Epub 2008 - Feb 11. - -PMID- 22258866 -OWN - NLM -STAT- MEDLINE -DCOM- 20121009 -LR - 20240330 -IS - 1937-5395 (Electronic) -IS - 1937-5387 (Print) -IS - 1937-5387 (Linking) -VI - 5 -IP - 2 -DP - 2012 Apr -TI - Left bundle branch block, an old-new entity. -PG - 107-16 -LID - 10.1007/s12265-011-9344-5 [doi] -AB - Left bundle branch block (LBBB) is generally associated with a poorer prognosis - in comparison to normal intraventricular conduction, but also in comparison to - right bundle branch block which is generally considered to be benign in the - absence of an underlying cardiac disorder like congenital heart disease. LBBB may - be the first manifestation of a more diffuse myocardial disease. The typical - surface ECG feature of LBBB is a prolongation of QRS above 0.11 s in combination - with a delay of the intrinsic deflection in leads V5 and V6 of more than 60 ms - and no septal q waves in leads I, V5, and V6 due to the abnormal septal - activation from right to left. LBBB may induce abnormalities in left ventricular - performance due to abnormal asynchronous contraction patterns which can be - compensated by biventricular pacing (resynchronization therapy). Asynchronous - electrical activation of the ventricles causes regional differences in workload - which may lead to asymmetric hypertrophy and left ventricular dilatation, - especially due to increased wall mass in late-activated regions, which may - aggravate preexisting left ventricular pumping performance or even induce it. Of - special interest are patients with LBBB and normal left ventricular dimensions - and normal ejection fraction at rest but who may present with an abnormal - increase in pulmonary artery pressure during exercise, production of lactate - during high-rate pacing, signs of ischemia on myocardial scintigrams (but no - coronary artery narrowing), and abnormal ultrastructural findings on myocardial - biopsy. For this entity, the term latent cardiomyopathy had been suggested - previously. -FAU - Breithardt, Günter -AU - Breithardt G -AD - Department of Cardiology and Angiology, Hospital of the University of Münster, - Albert-Schweitzer-Campus 1, Gebäude A1, 48149 Münster, Germany. - g.breithardt@uni-muenster.de -FAU - Breithardt, Ole-Alexander -AU - Breithardt OA -LA - eng -PT - Journal Article -PT - Review -DEP - 20120119 -PL - United States -TA - J Cardiovasc Transl Res -JT - Journal of cardiovascular translational research -JID - 101468585 -SB - IM -MH - *Bundle-Branch Block/complications/physiopathology/therapy -MH - *Cardiac Pacing, Artificial -MH - Electrocardiography -MH - Heart Failure/*etiology/physiopathology -MH - Humans -MH - Prognosis -MH - Ventricular Function, Left/*physiology -PMC - PMC3294212 -EDAT- 2012/01/20 06:00 -MHDA- 2012/10/10 06:00 -PMCR- 2012/01/19 -CRDT- 2012/01/20 06:00 -PHST- 2011/12/19 00:00 [received] -PHST- 2011/12/21 00:00 [accepted] -PHST- 2012/01/20 06:00 [entrez] -PHST- 2012/01/20 06:00 [pubmed] -PHST- 2012/10/10 06:00 [medline] -PHST- 2012/01/19 00:00 [pmc-release] -AID - 9344 [pii] -AID - 10.1007/s12265-011-9344-5 [doi] -PST - ppublish -SO - J Cardiovasc Transl Res. 2012 Apr;5(2):107-16. doi: 10.1007/s12265-011-9344-5. - Epub 2012 Jan 19. - -PMID- 17650775 -OWN - NLM -STAT- MEDLINE -DCOM- 20070910 -LR - 20220331 -IS - 1753-3740 (Print) -IS - 1753-3740 (Linking) -VI - 21 -IP - 2 -DP - 2007 Jun -TI - Perioperative use of anti-platelet drugs. -PG - 241-56 -AB - Performing a surgical procedure on a patient undergoing anti-platelet therapy - raises a dilemma: is it safer to withdraw the drugs and reduce the haemorrhagic - risk, or to maintain them and reduce the risk of myocardial ischaemic events? - Based on recent clinical data, this review concludes that the risk of coronary - thrombosis on anti-platelet drugs withdrawal is much higher than the risk of - surgical bleeding when maintaining them. In secondary prevention, aspirin is a - lifelong therapy and should never be stopped. Clopidogrel is mandatory as long as - the coronary stents are not fully endothelialized, which takes 6-24 weeks - depending on the technique used, but might be required for a longer period. -FAU - Chassot, Pierre-Guy -AU - Chassot PG -AD - Department of Anoesthesiology, University Hospital Lausanne (CHUV), Bugnon 46, - CH-1011 Lausanne, Switzerland. pierre-guy.chassot@chuv.ch -FAU - Delabays, Alain -AU - Delabays A -FAU - Spahn, Donat R -AU - Spahn DR -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Best Pract Res Clin Anaesthesiol -JT - Best practice & research. Clinical anaesthesiology -JID - 101121446 -RN - 0 (Platelet Aggregation Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Aspirin/therapeutic use -MH - Clopidogrel -MH - Coronary Thrombosis/*prevention & control -MH - Elective Surgical Procedures -MH - Hemorrhage/*chemically induced -MH - Humans -MH - Perioperative Care -MH - Platelet Aggregation Inhibitors/adverse effects/*therapeutic use -MH - Stents -MH - Ticlopidine/analogs & derivatives/therapeutic use -MH - Time Factors -MH - Treatment Outcome -RF - 87 -EDAT- 2007/07/27 09:00 -MHDA- 2007/09/11 09:00 -CRDT- 2007/07/27 09:00 -PHST- 2007/07/27 09:00 [pubmed] -PHST- 2007/09/11 09:00 [medline] -PHST- 2007/07/27 09:00 [entrez] -AID - S1521-6896(07)00018-3 [pii] -AID - 10.1016/j.bpa.2007.02.002 [doi] -PST - ppublish -SO - Best Pract Res Clin Anaesthesiol. 2007 Jun;21(2):241-56. doi: - 10.1016/j.bpa.2007.02.002. - -PMID- 20558892 -OWN - NLM -STAT- MEDLINE -DCOM- 20101019 -LR - 20220321 -IS - 1347-4820 (Electronic) -IS - 1346-9843 (Linking) -VI - 74 -IP - 7 -DP - 2010 Jul -TI - Sex and gender differences in myocardial hypertrophy and heart failure. -PG - 1265-73 -AB - Heart failure (HF) is a leading cause of cardiovascular mortality and morbidity - in the Western world. It affects men at younger age than women. Women have more - frequently diastolic HF, associated with the major risk factors of diabetes and - hypertension and men have more frequently systolic HF because of coronary artery - disease. Under stress, male hearts develop more easily pathological hypertrophy - with dilatation and poor systolic function than female hearts. Women with aortic - stenosis have more concentric hypertrophy with better systolic function, less - upregulation of extracellular matrix genes and better reversibility after - unloading. Stressed female hearts maintain energy metabolism better than male - hearts and are better protected against calcium overload. Estrogens and androgens - and their receptors are present in the myocardium and lead to coordinated - regulation of functionally relevant pathways. Atrial fibrillation (AF) is a more - ominous sign in women than in men. Men with end-stage cardiomyopathy more - frequently have auto-antibodies than women. Women receive less guideline-based - diagnostics and therapy. Expensive and invasive therapies such as advanced - pacemakers and transplantation are underused in women. Drug studies point at sex - differences in efficacy. Despite worse diagnostics and therapy, prognosis is - better in women than in men. -FAU - Regitz-Zagrosek, Vera -AU - Regitz-Zagrosek V -AD - Institute of Gender in Medicine and Center for Cardiovascular Research, Charité - University Medicine Berlin, Germany. vera.regitz-zagrosek@charite.de -FAU - Oertelt-Prigione, Sabine -AU - Oertelt-Prigione S -FAU - Seeland, Ute -AU - Seeland U -FAU - Hetzer, Roland -AU - Hetzer R -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100615 -PL - Japan -TA - Circ J -JT - Circulation journal : official journal of the Japanese Circulation Society -JID - 101137683 -SB - IM -MH - *Cardiomegaly/diagnosis/epidemiology/etiology -MH - Female -MH - Heart Failure/diagnosis/*epidemiology/etiology -MH - Humans -MH - Male -MH - Prognosis -MH - Sex Factors -EDAT- 2010/06/19 06:00 -MHDA- 2010/10/20 06:00 -CRDT- 2010/06/19 06:00 -PHST- 2010/06/19 06:00 [entrez] -PHST- 2010/06/19 06:00 [pubmed] -PHST- 2010/10/20 06:00 [medline] -AID - JST.JSTAGE/circj/CJ-10-0196 [pii] -AID - 10.1253/circj.cj-10-0196 [doi] -PST - ppublish -SO - Circ J. 2010 Jul;74(7):1265-73. doi: 10.1253/circj.cj-10-0196. Epub 2010 Jun 15. - -PMID- 21666054 -OWN - NLM -STAT- MEDLINE -DCOM- 20111115 -LR - 20210206 -IS - 1528-0020 (Electronic) -IS - 0006-4971 (Linking) -VI - 118 -IP - 9 -DP - 2011 Sep 1 -TI - Thrombogenicity and cardiovascular effects of ambient air pollution. -PG - 2405-12 -LID - 10.1182/blood-2011-04-343111 [doi] -AB - Exposure to air pollution is associated with adverse effects on health. In - particular, a strong epidemiologic association is observed between acute and - chronic exposures to particulate matter and the occurrence of cardiovascular - events, coronary artery disease, cerebrovascular disease and venous - thromboembolism, especially among older people and people with diabetes and - previous cardiovascular conditions. Multiple mechanisms have been postulated to - cause the increase in atherothrombotic and thromboembolic events, including the - activation by particulate matter of inflammatory pathways and hemostasis factors, - production of reactive oxygen species through the oxidative stress pathway, - alterations in vascular tone, and decreased heart rate variability (a marker of - cardiac autonomic dysfunction and a predictor of sudden cardiac death and - arrhythmias). Current knowledge on the biologic mechanisms and the clinical - effect of short- and long-term exposure to particulate air pollutants is - discussed, emphasizing that life expectancy improved significantly in sites where - air pollutants were controlled. -FAU - Franchini, Massimo -AU - Franchini M -AD - Department of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantova, - Italy. -FAU - Mannucci, Pier Mannuccio -AU - Mannucci PM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110610 -PL - United States -TA - Blood -JT - Blood -JID - 7603509 -RN - 0 (Particulate Matter) -SB - IM -CIN - Blood. 2011 Sep 1;118(9):2636-7. doi: 10.1182/blood-2011-07-367144. PMID: - 21885614 -MH - Air Pollution/*adverse effects -MH - Animals -MH - Arrhythmias, Cardiac/etiology/physiopathology -MH - Atherosclerosis/etiology/physiopathology -MH - Autonomic Nervous System/drug effects/physiopathology -MH - Cardiovascular Diseases/epidemiology/*etiology/physiopathology -MH - Heart Conduction System/drug effects/physiopathology -MH - Humans -MH - Inflammation/etiology -MH - Models, Biological -MH - Myocardial Infarction/epidemiology/etiology/physiopathology -MH - Oxidative Stress -MH - Particle Size -MH - Particulate Matter/*adverse effects/pharmacology -MH - Platelet Activation/drug effects -MH - Population Surveillance -MH - Stroke/epidemiology/etiology/physiopathology -MH - Thrombosis/epidemiology/*etiology/physiopathology -EDAT- 2011/06/15 06:00 -MHDA- 2011/11/16 06:00 -CRDT- 2011/06/14 06:00 -PHST- 2011/06/14 06:00 [entrez] -PHST- 2011/06/15 06:00 [pubmed] -PHST- 2011/11/16 06:00 [medline] -AID - S0006-4971(20)40732-3 [pii] -AID - 10.1182/blood-2011-04-343111 [doi] -PST - ppublish -SO - Blood. 2011 Sep 1;118(9):2405-12. doi: 10.1182/blood-2011-04-343111. Epub 2011 - Jun 10. - -PMID- 24183003 -OWN - NLM -STAT- MEDLINE -DCOM- 20141006 -LR - 20140207 -IS - 1879-1336 (Electronic) -IS - 1054-8807 (Linking) -VI - 23 -IP - 2 -DP - 2014 Mar-Apr -TI - Transcatheter aortic valve implantation: status and challenges. -PG - 65-70 -LID - S1054-8807(13)00182-8 [pii] -LID - 10.1016/j.carpath.2013.10.001 [doi] -AB - Calcific aortic valve disease of the elderly is the most prevalent - hemodynamically-significant valvular disease, and the most common lesion - requiring valve replacement in industrialized countries. Transcatheter aortic - valve implantation is a less invasive alternative to classical aortic valve - replacement that can provide a therapeutic option for high-risk or inoperable - patients with aortic stenosis. These devices must be biocompatible, have - excellent hemodynamic performance, be easy to insert, be securely anchored - without sutures, and be durable, without increased risk of thrombosis or - infection. To date, complications are related to the site of entry for insertion, - the site of implantation (aorta, coronary ostia, base of left ventricle), and to - the structure and design of the inserted device. However, as with any novel - technology unanticipated complications will develop. Goals for future development - will be to make the devices more effective, more durable, safer, and easier to - implant, so as to further improve outcome for patients with severe aortic - stenosis. The pathologist participating in research and development, and - examination of excised devices will have a critical role in improving outcome for - these patients. -CI - © 2014. -FAU - Fishbein, Gregory A -AU - Fishbein GA -AD - Department of Pathology and Laboratory Medicine David Geffen School of Medicine - at UCLA, 10833 Le Conte Avenue, CHS 13-145, Los Angeles, CA 90095-1732. - Electronic address: gfishbein@mednet.ucla.edu. -FAU - Schoen, Frederick J -AU - Schoen FJ -AD - Department of Pathology Brigham and Women's Hospital, 75 Francis Street, Boston, - MA 02115. -FAU - Fishbein, Michael C -AU - Fishbein MC -AD - Department of Pathology and Laboratory Medicine David Geffen School of Medicine - at UCLA, 10833 Le Conte Avenue, CHS 13-145, Los Angeles, CA 90095-1732. -LA - eng -PT - Journal Article -PT - Review -DEP - 20131008 -PL - United States -TA - Cardiovasc Pathol -JT - Cardiovascular pathology : the official journal of the Society for Cardiovascular - Pathology -JID - 9212060 -RN - Aortic Valve, Calcification of -SB - IM -MH - Aortic Valve/*pathology/physiopathology -MH - Aortic Valve Stenosis/diagnosis/physiopathology/*therapy -MH - Calcinosis/diagnosis/physiopathology/*therapy -MH - *Cardiac Catheterization/adverse effects/instrumentation -MH - Heart Valve Prosthesis -MH - Heart Valve Prosthesis Implantation/adverse effects/instrumentation/*methods -MH - Hemodynamics -MH - Humans -MH - Prosthesis Design -MH - Risk Factors -MH - Treatment Outcome -OTO - NOTNLM -OT - Aortic stenosis -OT - Aortic valve -OT - Prosthetic valve -OT - Transcatheter valve implantation -OT - Valvular disease -EDAT- 2013/11/05 06:00 -MHDA- 2014/10/07 06:00 -CRDT- 2013/11/05 06:00 -PHST- 2013/05/28 00:00 [received] -PHST- 2013/08/19 00:00 [revised] -PHST- 2013/10/01 00:00 [accepted] -PHST- 2013/11/05 06:00 [entrez] -PHST- 2013/11/05 06:00 [pubmed] -PHST- 2014/10/07 06:00 [medline] -AID - S1054-8807(13)00182-8 [pii] -AID - 10.1016/j.carpath.2013.10.001 [doi] -PST - ppublish -SO - Cardiovasc Pathol. 2014 Mar-Apr;23(2):65-70. doi: 10.1016/j.carpath.2013.10.001. - Epub 2013 Oct 8. - -PMID- 20230259 -OWN - NLM -STAT- MEDLINE -DCOM- 20100610 -LR - 20151119 -IS - 1744-8298 (Electronic) -IS - 1479-6678 (Linking) -VI - 6 -IP - 2 -DP - 2010 Mar -TI - Predictive value of C-reactive protein after drug-eluting stent implantation. -PG - 167-79 -LID - 10.2217/fca.09.159 [doi] -AB - During the last few decades, with the evolution of techniques and materials and - the increasing experience of operators, percutaneous coronary interventions (PCI) - have become an equally efficient alternative to coronary artery bypass grafts for - the treatment of most coronary stenoses. Bare-metal stent implantation - represented a major step forward, compared with plain old balloon angioplasty - (POBA), by improving the immediate angiographic success. However, the incidence - of in-stent restenosis (ISR) remained unacceptably high. Development of the - drug-eluting stent (DES) significantly improved the outcome of PCI by - dramatically abating the rate of ISR and reducing the incidence of target lesion - revascularization. However, ISR has not been eliminated and the persistence of - metal vessel scaffolding also raises concern regarding the occurrence of late or - very late stent thrombosis. POBA and stent implantation have been shown to induce - a local and systemic inflammatory response, whose magnitude is associated with - worse clinical outcome, and they increase the risk of ISR. C-reactive protein, a - marker of systemic inflammation, has been demonstrated to predict clinical and - angiographic outcome after POBA or bare-metal stent implantation. However, - conflicting data regarding the prognostic value of C-reactive protein following - DES implantation are available. In this paper, we review the literature regarding - the clinical and pathophysiological association between inflammation and - prognosis after DES implantation and suggest some possible therapeutic approaches - to reduce inflammatory burden with the aim to improve clinical and angiographic - outcome after PCI. -FAU - Montone, Rocco Antonio -AU - Montone RA -AD - Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy. - rocco.montone@gmail.com -FAU - Ferrante, Giuseppe -AU - Ferrante G -FAU - Bacà, Marco -AU - Bacà M -FAU - Niccoli, Giampaolo -AU - Niccoli G -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Future Cardiol -JT - Future cardiology -JID - 101239345 -RN - 0 (Immunosuppressive Agents) -RN - 9007-41-4 (C-Reactive Protein) -RN - P88XT4IS4D (Paclitaxel) -RN - W36ZG6FT64 (Sirolimus) -SB - IM -MH - Angioplasty, Balloon, Coronary -MH - Atherosclerosis/metabolism -MH - C-Reactive Protein/*analysis -MH - Coronary Angiography -MH - Coronary Restenosis/prevention & control -MH - Drug-Eluting Stents -MH - Humans -MH - Immunosuppressive Agents/pharmacology -MH - Inflammation/physiopathology -MH - Myocardial Infarction/epidemiology -MH - Paclitaxel/pharmacology -MH - Predictive Value of Tests -MH - Prognosis -MH - Sirolimus/pharmacology -RF - 111 -EDAT- 2010/03/17 06:00 -MHDA- 2010/06/11 06:00 -CRDT- 2010/03/17 06:00 -PHST- 2010/03/17 06:00 [entrez] -PHST- 2010/03/17 06:00 [pubmed] -PHST- 2010/06/11 06:00 [medline] -AID - 10.2217/fca.09.159 [doi] -PST - ppublish -SO - Future Cardiol. 2010 Mar;6(2):167-79. doi: 10.2217/fca.09.159. - -PMID- 16944066 -OWN - NLM -STAT- MEDLINE -DCOM- 20061204 -LR - 20081121 -IS - 0340-9937 (Print) -IS - 0340-9937 (Linking) -VI - 31 -IP - 5 -DP - 2006 Aug -TI - [Tako-Tsubo cardiomyopathy--a novel cardiac entity?]. -PG - 473-9 -AB - In recent years, a new cardiac syndrome with transient left ventricular - dysfunction has been widely reported in Japan. This new entity has been referred - to as "tako-tsubo cardiomyopathy" or "apical ballooning", named for the - particular shape of the end-systolic left ventricle in ventriculography. This - syndrome has also been reported to occur in the western population. The clinical - characteristics of this phenomenon have been described as follows: (1) acute - onset of reversible left ventricular apical wall motion abnormalities - (ballooning) with chest pain, (2) electrocardiographic changes (i.e., ST - elevation), (3) minimal myocardial enzymatic release, and (4) no significant - stenosis on coronary angiography. Severe emotional or physical stress usually - precedes this cardiomyopathy. A unifying mechanistic explanation responsible for - this acute but rapidly reversible contractile dysfunction is still lacking. - Several investigations suggested catecholamine-mediated cardiotoxicity or - coronary artery vasospasm, microvascular injury, an impaired fatty acid - metabolism, or transient obstruction of the left ventricular outflow. The optimal - treatment of patients presenting with this syndrome may depend on the stage of - condition, since various pathophysiological mechanisms underlie the final - clinical picture. -FAU - Nef, Holger M -AU - Nef HM -AD - Abteilung Kardiologie, Kerckhoff-Klinik, Bad Nauheim. h.nef@kerckhoff.mpg.de -FAU - Möllmann, Helge -AU - Möllmann H -FAU - Hamm, Christian W -AU - Hamm CW -FAU - Elsässer, Albrecht -AU - Elsässer A -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Tako-Tsubo-Kardiomyopathie--eine neue kardiale Entität? -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -RN - 0 (Catecholamines) -SB - IM -MH - Biopsy -MH - Cardiomyopathies/*diagnosis -MH - Catecholamines/blood -MH - Chest Pain/etiology -MH - Coronary Stenosis/diagnosis -MH - Diagnosis, Differential -MH - Humans -MH - Magnetic Resonance Imaging, Cine -MH - Myocardial Contraction/physiology -MH - Myocardium/pathology -MH - Prognosis -MH - Stress, Physiological/complications -MH - Syndrome -MH - Ventricular Dysfunction, Left/*diagnosis/etiology -RF - 46 -EDAT- 2006/09/01 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/09/01 09:00 -PHST- 2006/09/01 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/09/01 09:00 [entrez] -AID - 10.1007/s00059-006-2858-y [doi] -PST - ppublish -SO - Herz. 2006 Aug;31(5):473-9. doi: 10.1007/s00059-006-2858-y. - -PMID- 17541821 -OWN - NLM -STAT- MEDLINE -DCOM- 20071108 -LR - 20181113 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 12 -IP - 3-4 -DP - 2007 Dec -TI - Myocardial protection in man--from research concept to clinical practice. -PG - 345-62 -AB - Myocardial protection aims at preventing myocardial tissue loss: (a) In the acute - stage, i.e., during primary angioplasty in acute myocardial infarction. In this - setup, the attenuation of reperfusion injury is the main target. As a - "mechanical" means, post-conditioning has already been tried in man with - encouraging results. Pharmacologic interventions that could be of promise are - statins, insulin, peptide hormones, including erythropoietin, fibroblast growth - factor, and many others. (b) The patient with chronic coronary artery disease - offers another paradigm, with the target of avoidance of further myocyte loss - through apoptosis and inflammation. Various pharmacologic agents may prove useful - in this context, together with exercise and "mechanical" improvement of cardiac - function with attenuation of myocardial stretch, which by itself is a noxious - influence. A continuous effort toward acute and chronically preserving myocardial - integrity is a concept concerning both the researcher and the clinician. -FAU - Cokkinos, Dennis V -AU - Cokkinos DV -AD - 1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece. - cokkino1@otenet.gr -FAU - Pantos, Costas -AU - Pantos C -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Acute Disease -MH - *Biomedical Research -MH - Cardiotonic Agents -MH - *Evidence-Based Medicine -MH - Humans -MH - *Ischemic Preconditioning, Myocardial -MH - Myocardial Infarction/complications -MH - Myocardial Ischemia/physiopathology/*prevention & control -MH - *Myocardial Reperfusion -MH - *Myocardial Reperfusion Injury -MH - Myocardium/*pathology -MH - Thyroid Diseases -RF - 212 -EDAT- 2007/06/02 09:00 -MHDA- 2007/11/09 09:00 -CRDT- 2007/06/02 09:00 -PHST- 2007/06/02 09:00 [pubmed] -PHST- 2007/11/09 09:00 [medline] -PHST- 2007/06/02 09:00 [entrez] -AID - 10.1007/s10741-007-9030-5 [doi] -PST - ppublish -SO - Heart Fail Rev. 2007 Dec;12(3-4):345-62. doi: 10.1007/s10741-007-9030-5. - -PMID- 17438377 -OWN - NLM -STAT- MEDLINE -DCOM- 20070501 -LR - 20171116 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 15 -IP - 3 -DP - 2007 May-Jun -TI - Nutriceuticals in cardiovascular disease: psyllium. -PG - 116-22 -AB - In recent years, there has been a growing interest in the use of dietary fiber in - health maintenance and disease prevention. A deficiency of fiber in the Western - diet may be contributing to the current epidemics of diabetes mellitus, coronary - artery disease (CAD), and colonic cancer. The awareness of fiber as a dietary - supplement may have contributed to the reported 30% decline in death rate from - CAD observed over the past 15 years. Psyllium is a soluble gel-forming fiber that - has been shown to bind to the bile acids in the gut and prevent their normal - reabsorption, similar to the bile acid sequestrant drugs. Psyllium is useful as - an adjunct to dietary therapy (step 1 or step 2 American Heart Association [AHA] - diet) in the treatment of patients with mild-to-moderate hypercholesterolemia. In - combination with other cholesterol-lowering drugs, such as statins, psyllium - provides an added benefit on cholesterol lowering, and is well tolerated and - cost-effective. -FAU - Petchetti, Lavanya -AU - Petchetti L -AD - Department of Medicine, Mt. Vernon Hospital, Mt. Vernon, New York, USA. -FAU - Frishman, William H -AU - Frishman WH -FAU - Petrillo, Richard -AU - Petrillo R -FAU - Raju, Kolanuvada -AU - Raju K -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Dietary Fiber) -RN - 8063-16-9 (Psyllium) -SB - IM -MH - Cardiovascular Diseases/drug therapy/*mortality/*prevention & control -MH - Dietary Fiber/*therapeutic use -MH - Dose-Response Relationship, Drug -MH - Drug Administration Schedule -MH - Female -MH - Humans -MH - Hypercholesterolemia/diagnosis/*drug therapy/mortality -MH - Male -MH - Prognosis -MH - Psyllium/adverse effects/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - Survival Analysis -MH - Treatment Outcome -RF - 51 -EDAT- 2007/04/18 09:00 -MHDA- 2007/05/02 09:00 -CRDT- 2007/04/18 09:00 -PHST- 2007/04/18 09:00 [pubmed] -PHST- 2007/05/02 09:00 [medline] -PHST- 2007/04/18 09:00 [entrez] -AID - 00045415-200705000-00002 [pii] -AID - 10.1097/01.crd.0000242964.74467.27 [doi] -PST - ppublish -SO - Cardiol Rev. 2007 May-Jun;15(3):116-22. doi: 10.1097/01.crd.0000242964.74467.27. - -PMID- 21538815 -OWN - NLM -STAT- MEDLINE -DCOM- 20111207 -LR - 20250529 -IS - 1542-0760 (Electronic) -IS - 1542-0752 (Linking) -VI - 91 -IP - 6 -DP - 2011 Jun -TI - TGFβ signaling and congenital heart disease: Insights from mouse studies. -PG - 423-34 -LID - 10.1002/bdra.20794 [doi] -AB - Transforming growth factor β (TGFβ) regulates one of the major signaling pathways - that control tissue morphogenesis. In vitro experiments using heart explants - indicated the importance of this signaling pathway for the generation of cushion - mesenchymal cells, which ultimately contribute to the valves and septa of the - mature heart. Recent advances in mouse genetics have enabled in vivo - investigation into the roles of individual ligands, receptors, and coreceptors of - this pathway, including investigation of the tissue specificity of these roles in - heart development. This work has revealed that (1) cushion mesenchyme can form in - the absence of TGFβ signaling, although mesenchymal cell numbers may be - misregulated; (2) TGFβ signaling is essential for correct remodeling of the - cushions, particularly those of the outflow tract; (3) TGFβ signaling also has a - role in ensuring accurate remodeling of the pharyngeal arch arteries to form the - mature aortic arch; and (4) mesenchymal cells derived from the epicardium require - TGFβ signaling to promote their differentiation to vascular smooth muscle cells - to support the coronary arteries. In addition, a mouse genetics approach has also - been used to investigate the disease pathogenesis of Loeys-Dietz syndrome, a - familial autosomal dominant human disorder characterized by a dilated aortic - root, and associated with mutations in the two TGFβ signaling receptor genes, - TGFBR1 and TGFBR2. Further important insights are likely as this exciting work - progresses. -CI - Copyright © 2011 Wiley-Liss, Inc. -FAU - Arthur, Helen M -AU - Arthur HM -AD - Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United - Kingdom. helen.arthur@ncl.ac.uk. -FAU - Bamforth, Simon D -AU - Bamforth SD -LA - eng -GR - FS/08/001/23666/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110428 -PL - United States -TA - Birth Defects Res A Clin Mol Teratol -JT - Birth defects research. Part A, Clinical and molecular teratology -JID - 101155107 -RN - 0 (Transforming Growth Factor beta) -SB - IM -MH - Animals -MH - Heart Defects, Congenital/genetics/*metabolism -MH - Humans -MH - Mesoderm/embryology -MH - Mice -MH - Muscle, Smooth, Vascular/embryology -MH - *Signal Transduction -MH - Transforming Growth Factor beta/genetics/*metabolism -MH - Ventricular Remodeling -EDAT- 2011/05/04 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2011/05/04 06:00 -PHST- 2010/11/15 00:00 [received] -PHST- 2011/01/17 00:00 [revised] -PHST- 2011/01/28 00:00 [accepted] -PHST- 2011/05/04 06:00 [entrez] -PHST- 2011/05/04 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -AID - 10.1002/bdra.20794 [doi] -PST - ppublish -SO - Birth Defects Res A Clin Mol Teratol. 2011 Jun;91(6):423-34. doi: - 10.1002/bdra.20794. Epub 2011 Apr 28. - -PMID- 23580344 -OWN - NLM -STAT- MEDLINE -DCOM- 20130730 -LR - 20220318 -IS - 1179-2019 (Electronic) -IS - 1174-5878 (Linking) -VI - 15 -IP - 3 -DP - 2013 Jun -TI - Managing cardiovascular risk in overweight children and adolescents. -PG - 181-90 -LID - 10.1007/s40272-013-0011-y [doi] -AB - The scientific, medical, and lay communities are currently confronted with a - serious medical and public health problem related to the marked non-remitting - worldwide epidemic of obesity. This ever-increasing prevalence of obesity is - accompanied by a host of inherently associated co-morbidities. As a result, - obesity is fast becoming the major cause of premature death in the developed - world. As pediatric and adult cardiologists, we have seen a dramatic increase in - office referrals of overweight and obese children and adolescents, who already - have obesity-related degenerative disease processes such as hypertension, - dyslipidemia, the metabolic syndrome, and type 2 diabetes mellitus, as well as - manifestations of early preclinical atherosclerotic cardiovascular disease, not - previously observed in this age group. This article presents a review of the - literature and recent scientific statements and recommendations issued by the - American Heart Association (AHA) and the American Academy of Pediatrics (AAP) - regarding the metabolic abnormalities associated with obesity, including newer - identification and treatment strategies for obesity, dyslipidemia, and early - subclinical coronary artery disease seen in high-risk children and adolescents. -FAU - Dhuper, Sarita -AU - Dhuper S -AD - Department of Pediatric Cardiology, Brookdale University Hospital and Medical - Center, 1 Brookdale Plaza, Room 300CHC, Brooklyn, NY 11212, USA. - sdhuper@brookdale.edu -FAU - Buddhe, Sujatha -AU - Buddhe S -FAU - Patel, Sunil -AU - Patel S -LA - eng -PT - Journal Article -PT - Review -PL - Switzerland -TA - Paediatr Drugs -JT - Paediatric drugs -JID - 100883685 -RN - 0 (Hypolipidemic Agents) -SB - IM -MH - Adolescent -MH - Bariatric Surgery -MH - Cardiovascular Diseases/etiology -MH - Child -MH - Dyslipidemias/complications/*drug therapy -MH - Exercise -MH - Humans -MH - Hypolipidemic Agents/*therapeutic use -MH - Metabolic Syndrome/complications -MH - Obesity/complications/physiopathology/*therapy -MH - Prevalence -MH - Risk Factors -EDAT- 2013/04/13 06:00 -MHDA- 2013/07/31 06:00 -CRDT- 2013/04/13 06:00 -PHST- 2013/04/13 06:00 [entrez] -PHST- 2013/04/13 06:00 [pubmed] -PHST- 2013/07/31 06:00 [medline] -AID - 10.1007/s40272-013-0011-y [doi] -PST - ppublish -SO - Paediatr Drugs. 2013 Jun;15(3):181-90. doi: 10.1007/s40272-013-0011-y. - -PMID- 24348732 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20211021 -IS - 1741-427X (Print) -IS - 1741-4288 (Electronic) -IS - 1741-427X (Linking) -VI - 2013 -DP - 2013 -TI - Tai chi chuan exercise for patients with cardiovascular disease. -PG - 983208 -LID - 10.1155/2013/983208 [doi] -LID - 983208 -AB - Exercise training is the cornerstone of rehabilitation for patients with - cardiovascular disease (CVD). Although high-intensity exercise has significant - cardiovascular benefits, light-to-moderate intensity aerobic exercise also offers - health benefits. With lower-intensity workouts, patients may be able to exercise - for longer periods of time and increase the acceptance of exercise, particularly - in unfit and elderly patients. Tai Chi Chuan (Tai Chi) is a traditional Chinese - mind-body exercise. The exercise intensity of Tai Chi is light to moderate, - depending on its training style, posture, and duration. Previous research has - shown that Tai Chi enhances aerobic capacity, muscular strength, balance, and - psychological well-being. Additionally, Tai Chi training has significant benefits - for common cardiovascular risk factors, such as hypertension, diabetes mellitus, - dyslipidemia, poor exercise capacity, endothelial dysfunction, and depression. - Tai Chi is safe and effective in patients with acute myocardial infarction (AMI), - coronary artery bypass grafting (CABG) surgery, congestive heart failure (HF), - and stroke. In conclusion, Tai Chi has significant benefits to patients with - cardiovascular disease, and it may be prescribed as an alternative exercise - program for selected patients with CVD. -FAU - Lan, Ching -AU - Lan C -AD - Department of Physical Medicine and Rehabilitation, National Taiwan University - Hospital and National Taiwan University, College of Medicine, 7 Chung-Shan South - Road, Taipei 100, Taiwan. -FAU - Chen, Ssu-Yuan -AU - Chen SY -AD - Department of Physical Medicine and Rehabilitation, National Taiwan University - Hospital and National Taiwan University, College of Medicine, 7 Chung-Shan South - Road, Taipei 100, Taiwan. -FAU - Wong, May-Kuen -AU - Wong MK -AD - Department of Physical Medicine and Rehabilitation, Chang-Gung Memorial Hospital - and Department of Physical Therapy, Post-Graduate Institute of Rehabilitation - Science, Chang-Gung University, Taoyuan 333, Taiwan. -FAU - Lai, Jin Shin -AU - Lai JS -AD - Department of Physical Medicine and Rehabilitation, National Taiwan University - Hospital and National Taiwan University, College of Medicine, 7 Chung-Shan South - Road, Taipei 100, Taiwan. -LA - eng -PT - Journal Article -PT - Review -DEP - 20131117 -PL - United States -TA - Evid Based Complement Alternat Med -JT - Evidence-based complementary and alternative medicine : eCAM -JID - 101215021 -PMC - PMC3855938 -EDAT- 2013/12/19 06:00 -MHDA- 2013/12/19 06:01 -PMCR- 2013/11/17 -CRDT- 2013/12/19 06:00 -PHST- 2012/12/17 00:00 [received] -PHST- 2013/08/19 00:00 [revised] -PHST- 2013/09/23 00:00 [accepted] -PHST- 2013/12/19 06:00 [entrez] -PHST- 2013/12/19 06:00 [pubmed] -PHST- 2013/12/19 06:01 [medline] -PHST- 2013/11/17 00:00 [pmc-release] -AID - 10.1155/2013/983208 [doi] -PST - ppublish -SO - Evid Based Complement Alternat Med. 2013;2013:983208. doi: 10.1155/2013/983208. - Epub 2013 Nov 17. - -PMID- 18629369 -OWN - NLM -STAT- MEDLINE -DCOM- 20080904 -LR - 20241219 -IS - 1176-6344 (Print) -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Linking) -VI - 4 -IP - 1 -DP - 2008 -TI - Chronic heart failure in Japan: implications of the CHART studies. -PG - 103-13 -AB - The prognosis of patients with chronic heart failure (CHF) still remains poor, - despite the recent advances in medical and surgical treatment. Furthermore, CHF - is a major public health problem in most industrialized countries where the - elderly population is rapidly increasing. Although the prevalence and mortality - of CHF used to be relatively low in Japan, the disorder has been markedly - increasing due to the rapid aging of the society and the Westernization of - lifestyle that facilitates the development of coronary artery disease. The - Chronic Heart Failure Analysis and Registry in the Tohoku District (CHART)-1 - study was one of the largest cohorts in Japan. The study has clarified the - characteristics and prognosis of Japanese patients with CHF, demonstrating that - their prognosis was similarly poor compared with those in Western countries. - However, we still need evidence for the prevention and treatment of CHF based on - the large cohort studies or randomized treatment trials in the Japanese - population. Since the strategy for CHF management is now changing from treatment - to prevention, a larger-size prospective cohort, called the CHART-2 study, has - been initiated to evaluate the risk factors of CHF in Japan. This review - summarizes the current status of CHF studies in Japan and discusses their future - perspectives. -FAU - Shiba, Nobuyuki -AU - Shiba N -AD - Department of Cardiovascular Medicine, Department of Evidence-Based - Cardiovascular Medicine, Tohoku University Graduate School of Medicine Sendai - City, Japan. nshiba@cardio.med.tohoku.ac.jp -FAU - Shimokawa, Hiroaki -AU - Shimokawa H -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Aging/physiology -MH - Angiotensin II Type 1 Receptor Blockers/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Cause of Death -MH - Chronic Disease -MH - Clinical Trials as Topic -MH - Heart Failure/drug therapy/*epidemiology/ethnology/physiopathology -MH - Humans -MH - Insurance, Health -MH - Japan/epidemiology -MH - Prevalence -MH - Prognosis -MH - Registries -MH - Risk Factors -PMC - PMC2464764 -OTO - NOTNLM -OT - Japanese -OT - aging -OT - heart failure -EDAT- 2008/07/17 09:00 -MHDA- 2008/09/05 09:00 -PMCR- 2008/06/01 -CRDT- 2008/07/17 09:00 -PHST- 2008/07/17 09:00 [pubmed] -PHST- 2008/09/05 09:00 [medline] -PHST- 2008/07/17 09:00 [entrez] -PHST- 2008/06/01 00:00 [pmc-release] -AID - 10.2147/vhrm.2008.04.01.103 [doi] -PST - ppublish -SO - Vasc Health Risk Manag. 2008;4(1):103-13. doi: 10.2147/vhrm.2008.04.01.103. - -PMID- 20632955 -OWN - NLM -STAT- MEDLINE -DCOM- 20110826 -LR - 20220311 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 16 -IP - 26 -DP - 2010 -TI - Takotsubo cardiomyopathy. -PG - 2910-7 -AB - Takotsubo cardiomyopathy was first reported in Japan in 1990. Recently, an - increasing number of case reports and reviews of takotsubo cardiomyopathy has - been published worldwide, including atypical cases with inverted takotsubo - cardiomyopathy or incidental coronary artery disease. To date, there has been no - guideline for worldwide consensus on takotsubo cardiomyopathy diagnostic criteria - and treatment. Although the exact mechanism of takotsubo cardiomyopathy remains - to be elucidated, it has been suggested that catecholamine cardiotoxicity plays a - crucial role. Here, we summarize the current case reports and reviews in regard - to diagnosis, cardiac biomarkers, electrocardiogram, cardiac imaging, mechanism, - treatment and prognosis in order to establish a deeper understanding of this - syndrome. -FAU - Kida, Keisuke -AU - Kida K -AD - Division of Cardiology, Department of Internal Medicine, St. Marianna University - School of Medicine 2-16-1 Sugao Miyamae, Kawasaki, Japan. - heart-kida@marianna-u.ac.jp -FAU - Akashi, Yoshihiro J -AU - Akashi YJ -FAU - Fazio, Giovanni -AU - Fazio G -FAU - Novo, Salvatore -AU - Novo S -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -SB - IM -MH - Animals -MH - Cardiac Catheterization/methods -MH - Diagnostic Imaging/methods -MH - Electrocardiography/methods -MH - Humans -MH - Takotsubo Cardiomyopathy/*diagnosis/*therapy -EDAT- 2010/07/17 06:00 -MHDA- 2011/08/30 06:00 -CRDT- 2010/07/17 06:00 -PHST- 2010/06/03 00:00 [received] -PHST- 2010/07/01 00:00 [accepted] -PHST- 2010/07/17 06:00 [entrez] -PHST- 2010/07/17 06:00 [pubmed] -PHST- 2011/08/30 06:00 [medline] -AID - BSP/CPD/E-Pub/000153 [pii] -AID - 10.2174/138161210793176509 [doi] -PST - ppublish -SO - Curr Pharm Des. 2010;16(26):2910-7. doi: 10.2174/138161210793176509. - -PMID- 16894256 -OWN - NLM -STAT- MEDLINE -DCOM- 20070109 -LR - 20191110 -IS - 1541-9215 (Print) -IS - 1541-9215 (Linking) -VI - 4 -IP - 3 -DP - 2006 Summer -TI - The 5-year projection on the future of interventional cardiology. -PG - 195-201 -AB - Interventional cardiology has revolutionized modern cardiovascular care not only - with the introduction of new approaches to the treatment of coronary artery - disease, but also with the development of new invasive approaches to - electrophysiologic procedures and the treatment of noncoronary vascular beds. - This revolution continues to gather speed. Creative solutions continue to be - proposed, evaluated, and then brought to the patient care arena. Issues remain, - but these identify opportunities for continuing improvement. -FAU - Holmes, David R Jr -AU - Holmes DR Jr -AD - Mayo Clinic, Rochester, MN 55905, USA. holmes.david@mayo.edu -FAU - Rihal, Charanjit -AU - Rihal C -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Am Heart Hosp J -JT - The American heart hospital journal -JID - 101156064 -SB - IM -MH - Cardiac Surgical Procedures/trends -MH - Cardiology/*trends -MH - Cardiovascular Diseases/diagnosis/therapy -MH - Cell Transplantation/trends -MH - Humans -MH - Myocytes, Cardiac/transplantation -MH - Stroke/prevention & control -MH - United States -RF - 73 -EDAT- 2006/08/09 09:00 -MHDA- 2007/01/11 09:00 -CRDT- 2006/08/09 09:00 -PHST- 2006/08/09 09:00 [pubmed] -PHST- 2007/01/11 09:00 [medline] -PHST- 2006/08/09 09:00 [entrez] -AID - 10.1111/j.1541-9215.2006.05655.x [doi] -PST - ppublish -SO - Am Heart Hosp J. 2006 Summer;4(3):195-201. doi: 10.1111/j.1541-9215.2006.05655.x. - -PMID- 21482317 -OWN - NLM -STAT- MEDLINE -DCOM- 20110624 -LR - 20110412 -IS - 1873-2623 (Electronic) -IS - 0041-1345 (Linking) -VI - 43 -IP - 3 Suppl -DP - 2011 Apr -TI - Update and review: state-of-the-art management of cytomegalovirus infection and - disease following thoracic organ transplantation. -PG - S1-S17 -LID - 10.1016/j.transproceed.2011.02.069 [doi] -AB - PURPOSE: Cytomegalovirus (CMV) is among the most important viral pathogens - affecting solid organ recipients. The direct effects of CMV (eg, infection and - its sequela; tissue invasive disease) are responsible for significant morbidity - and mortality. In addition, CMV is associated with numerous indirect effects, - including immunomodulatory effects, acute and chronic rejection, and - opportunistic infections. Due to the potentially devastating effects of CMV, - transplant surgeons and physicians have been challenged to fully understand this - infectious complication and find the best ways to prevent and treat it to ensure - optimal patient outcomes. SUMMARY: Lung, heart, and heart-lung recipients are at - considerably high risk of CMV infection. Both direct and indirect effects of CMV - in these populations have potentially lethal consequences. The use of available - treatment options depend on the level of risk of each patient population for CMV - infection and disease. Those at the highest risk are CMV negative recipients of - CMV positive organs (D+/R-), followed by D+/R+, and D-/R+. More than 1 guideline - exists delineating prevention and treatment options for CMV, and new guidelines - are being developed. It is hoped that new treatment algorithms will provide - further guidance to the transplantation community. The first part describes the - overall effects of CMV, both direct and indirect; risk factors for CMV infection - and disease; methods of diagnosis; and currently available therapies for - prevention and treatment. Part 2 similarly addresses antiviral-resistant CMV, - summarizing incidence, risk factors, methods of diagnosis, and treatment options. - Parts 3 and 4 present cases to illustrate issues surrounding CMV in heart and - lung transplantation, respectively. Part 3 discusses the possible mechanisms by - which CMV can cause damage to the coronary allograft and potential techniques of - avoiding such damage, with emphasis on fostering strong CMV-specific immunity. - Part 4 highlights the increased incidence of CMV infection and disease among lung - transplant recipients and its detrimental effect on survival. The possible - benefits of extended-duration anti-CMV prophylaxis are explored, as are those of - combination prophylaxis with valganciclovir and CMVIG. CONCLUSION: Through - improved utilization of information regarding optimized antiviral therapy for - heart and lung transplant recipients to prevent and treat CMV infection and - disease and through increased understanding of clinical strategies to assess, - treat, and monitor patients at high risk for CMV recurrence and resistance, the - health care team will be able to provide the coordinated effort needed to improve - patient outcomes. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Snydman, David R -AU - Snydman DR -AD - Chief of Division of Geographic Medicine and Infectious Diseases, Hospital - Epidemiologist, Tufts Medical Center, Boston, Massachusetts, USA. -FAU - Limaye, Ajit P -AU - Limaye AP -FAU - Potena, Luciano -AU - Potena L -FAU - Zamora, Martin R -AU - Zamora MR -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - Transplant Proc -JT - Transplantation proceedings -JID - 0243532 -RN - 0 (Antiviral Agents) -SB - IM -MH - Adult -MH - Antiviral Agents/*therapeutic use -MH - Cytomegalovirus Infections/*drug therapy/virology -MH - Drug Resistance, Viral -MH - Female -MH - Graft Survival -MH - Heart Transplantation/*adverse effects -MH - Heart-Lung Transplantation/adverse effects -MH - Humans -MH - Lung Transplantation/*adverse effects -MH - Male -MH - Middle Aged -MH - Recurrence -MH - Risk Factors -MH - Treatment Outcome -EDAT- 2011/04/22 06:00 -MHDA- 2011/06/28 06:00 -CRDT- 2011/04/13 06:00 -PHST- 2011/04/13 06:00 [entrez] -PHST- 2011/04/22 06:00 [pubmed] -PHST- 2011/06/28 06:00 [medline] -AID - S0041-1345(11)00428-3 [pii] -AID - 10.1016/j.transproceed.2011.02.069 [doi] -PST - ppublish -SO - Transplant Proc. 2011 Apr;43(3 Suppl):S1-S17. doi: - 10.1016/j.transproceed.2011.02.069. - -PMID- 26005484 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20150525 -LR - 20200930 -IS - 1735-5370 (Print) -IS - 2008-2371 (Electronic) -IS - 1735-5370 (Linking) -VI - 8 -IP - 4 -DP - 2013 Oct 28 -TI - Cardiovascular considerations in antidepressant therapy: an evidence-based - review. -PG - 169-76 -AB - There is a definite correlation between cardiovascular diseases and depressive - disorders. Nevertheless, many aspects of this association have yet to be fully - elucidated. Up to half of coronary artery disease patients are liable to suffer - from some depressive symptoms, with approximately 20% receiving a diagnosis of - major depressive disorders. Pharmacotherapy is a key factor in the management of - major depression, not least in patients with chronic diseases who are likely to - fail to show proper compliance and response to non-pharmacological interventions. - Antidepressants are not deemed completely safe. Indeed, numerous side effects - have been reported with the administration of antidepressants, among which - cardiovascular adverse events are of paramount importance owing to their - disabling and life-threatening nature. We aimed to re-examine some of the salient - issues in antidepressant therapy vis-à-vis cardiovascular considerations, which - should be taken into account when prescribing such medications. -FAU - Yekehtaz, Habibeh -AU - Yekehtaz H -AD - Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical - Sciences, Tehran, Iran. -FAU - Farokhnia, Mehdi -AU - Farokhnia M -AD - Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical - Sciences, Tehran, Iran. -FAU - Akhondzadeh, Shahin -AU - Akhondzadeh S -AD - Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical - Sciences, Tehran, Iran. -LA - eng -PT - Journal Article -PT - Review -PL - Iran -TA - J Tehran Heart Cent -JT - The journal of Tehran Heart Center -JID - 101289255 -PMC - PMC4434967 -OTO - NOTNLM -OT - Antidepressive agents -OT - Cardiovascular diseases -OT - Depressive disorder, major -EDAT- 2013/10/28 00:00 -MHDA- 2013/10/28 00:01 -PMCR- 2013/10/28 -CRDT- 2015/05/26 06:00 -PHST- 2013/07/23 00:00 [received] -PHST- 2013/08/17 00:00 [accepted] -PHST- 2015/05/26 06:00 [entrez] -PHST- 2013/10/28 00:00 [pubmed] -PHST- 2013/10/28 00:01 [medline] -PHST- 2013/10/28 00:00 [pmc-release] -PST - ppublish -SO - J Tehran Heart Cent. 2013 Oct 28;8(4):169-76. - -PMID- 22698534 -OWN - NLM -STAT- MEDLINE -DCOM- 20121029 -LR - 20161125 -IS - 1876-7591 (Electronic) -IS - 1876-7591 (Linking) -VI - 5 -IP - 6 -DP - 2012 Jun -TI - Cardiac imaging modalities with ionizing radiation: the role of informed consent. -PG - 634-40 -LID - 10.1016/j.jcmg.2011.11.023 [doi] -AB - Informed consent ideally results in patient autonomy and rational health care - decisions. Frequently, patients face complex medical decisions that require a - delicate balancing of anticipated benefits and potential risks, which is the - concept of informed consent. This balancing process requires an understanding of - available medical evidence and alternative medical options, and input from - experienced physicians. The informed consent doctrine places a positive - obligation on physicians to partner with patients as they try to make the best - decision for their specific medical situation. The high prevalence and mortality - related to heart disease in our society has led to increased cardiac imaging with - modalities that use ionizing radiation. This paper reviews how physicians can - meet the ideals of informed consent when considering cardiac imaging with - ionizing radiation, given the limited evidence for risks and benefits. The goal - is an informed patient making rational choices based on available medical - information. -CI - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Paterick, Timothy E -AU - Paterick TE -AD - Aurora Cardiovascular Services, Aurora Sinai/Aurora St Luke's Medical Centers, - University of Wisconsin School of Medicine and Public Health, Milwaukee, - Wisconsin 53215, USA. publishing15@aurora.org -FAU - Jan, M Fuad -AU - Jan MF -FAU - Paterick, Zachary R -AU - Paterick ZR -FAU - Tajik, A Jamil -AU - Tajik AJ -FAU - Gerber, Thomas C -AU - Gerber TC -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - JACC Cardiovasc Imaging -JT - JACC. Cardiovascular imaging -JID - 101467978 -SB - IM -MH - Coronary Angiography -MH - *Diagnostic Imaging/adverse effects/ethics/methods -MH - Evidence-Based Medicine -MH - Heart Diseases/*diagnosis/diagnostic imaging/mortality -MH - Humans -MH - *Informed Consent/ethics/legislation & jurisprudence -MH - Liability, Legal -MH - Perfusion Imaging -MH - Physician-Patient Relations -MH - Predictive Value of Tests -MH - Prognosis -MH - *Radiation Dosage -MH - Risk Assessment -MH - Risk Factors -MH - Severity of Illness Index -MH - Tomography, Emission-Computed -MH - Tomography, X-Ray Computed -MH - Truth Disclosure -EDAT- 2012/06/16 06:00 -MHDA- 2012/10/30 06:00 -CRDT- 2012/06/16 06:00 -PHST- 2011/06/27 00:00 [received] -PHST- 2011/11/10 00:00 [revised] -PHST- 2011/11/21 00:00 [accepted] -PHST- 2012/06/16 06:00 [entrez] -PHST- 2012/06/16 06:00 [pubmed] -PHST- 2012/10/30 06:00 [medline] -AID - S1936-878X(12)00276-8 [pii] -AID - 10.1016/j.jcmg.2011.11.023 [doi] -PST - ppublish -SO - JACC Cardiovasc Imaging. 2012 Jun;5(6):634-40. doi: 10.1016/j.jcmg.2011.11.023. - -PMID- 18360864 -OWN - NLM -STAT- MEDLINE -DCOM- 20080512 -LR - 20151119 -IS - 1522-726X (Electronic) -IS - 1522-1946 (Linking) -VI - 71 -IP - 5 -DP - 2008 Apr 1 -TI - Assessment of operability of congenital cardiac shunts with increased pulmonary - vascular resistance. -PG - 665-70 -LID - 10.1002/ccd.21446 [doi] -AB - Patients with large left to right shunts as a result of congenital heart disease - can develop changes in pulmonary vasculature that are initially reversible. It is - critical in these patients to determine whether closure of the defect would - reverse some of the changes in the pulmonary vasculature. A comprehensive - clinical and noninvasive evaluation often allows classification in the extremes - of the spectrum, but for borderline situations, cardiac catheterization is - traditionally undertaken. It is important to obtain invasive data meticulously - and efficiently recognizing that the numbers only offer a snapshot and may not be - representative of the usual physiologic state of the patient. There are, in - addition, several caveats that need to be considered while calculating flows and - resistances in these patients. Currently a holistic approach that combines - clinical, noninvasive, and invasive data may be the only realistic way of making - a decision regarding operability in this challenging group of patients with shunt - lesions and elevated pulmonary vascular resistance. -CI - Copyright 2008 Wiley-Liss, Inc. -FAU - Viswanathan, Sangeetha -AU - Viswanathan S -AD - Department of Paediatric Cardiology, Leeds General Infirmary, Leeds, United - Kingdom. -FAU - Kumar, R Krishna -AU - Kumar RK -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Catheter Cardiovasc Interv -JT - Catheterization and cardiovascular interventions : official journal of the - Society for Cardiac Angiography & Interventions -JID - 100884139 -RN - 31C4KY9ESH (Nitric Oxide) -RN - S88TT14065 (Oxygen) -SB - IM -MH - Balloon Occlusion -MH - Blood Flow Velocity -MH - Blood Pressure -MH - Cardiac Catheterization -MH - *Cardiac Surgical Procedures -MH - *Coronary Circulation -MH - Heart Defects, Congenital/complications/diagnosis/physiopathology/*surgery -MH - Humans -MH - Hypertension, Pulmonary/*etiology/pathology/physiopathology/surgery -MH - Lung/blood supply/pathology -MH - Nitric Oxide -MH - Oxygen -MH - *Patient Selection -MH - Pulmonary Artery/*physiopathology -MH - *Pulmonary Circulation -MH - Regional Blood Flow -MH - Severity of Illness Index -MH - Treatment Outcome -MH - *Vascular Resistance -RF - 20 -EDAT- 2008/03/25 09:00 -MHDA- 2008/05/13 09:00 -CRDT- 2008/03/25 09:00 -PHST- 2008/03/25 09:00 [pubmed] -PHST- 2008/05/13 09:00 [medline] -PHST- 2008/03/25 09:00 [entrez] -AID - 10.1002/ccd.21446 [doi] -PST - ppublish -SO - Catheter Cardiovasc Interv. 2008 Apr 1;71(5):665-70. doi: 10.1002/ccd.21446. - -PMID- 23114995 -OWN - NLM -STAT- MEDLINE -DCOM- 20140701 -LR - 20230525 -IS - 1573-7322 (Electronic) -IS - 1382-4147 (Linking) -VI - 18 -IP - 6 -DP - 2013 Nov -TI - Immune-mediated and autoimmune myocarditis: clinical presentation, diagnosis and - management. -PG - 715-32 -LID - 10.1007/s10741-012-9364-5 [doi] -AB - According to the current WHO classification of cardiomyopathies, myocarditis is - an inflammatory disease of the myocardium and is diagnosed by endomyocardial - biopsy using established histological, immunological and immunohistochemical - criteria; it may be idiopathic, infectious or autoimmune and may heal or lead to - dilated cardiomyopathy (DCM). DCM is characterized by dilatation and impaired - contraction of the left or both ventricles; it may be idiopathic, - familial/genetic, viral and/or immune. The diagnosis of DCM requires exclusion of - known, specific causes of heart failure, including coronary artery disease. On - endomyocardial biopsy, there is myocyte loss, compensatory hypertrophy, fibrous - tissue and immunohistochemical findings consistent with chronic inflammation - (myocarditis) in 30-40 % of cases. In a patient subset, myocarditis and DCM - represent the acute and chronic stages of an inflammatory disease of the - myocardium, which can be viral, post-infectious immune or primarily - organ-specific autoimmune. Here, we review the clinical presentation, - etiopathogenetic diagnostic criteria, and management of immune-mediated and - autoimmune myocarditis. -FAU - Caforio, Alida L P -AU - Caforio AL -AD - Division of Cardiology, Department of Cardiological, Thoracic and Vascular - Sciences, Centro "V. Gallucci", University of Padova-Policlinico, Via - Giustiniani, 2, 35128, Padua, Italy, alida.caforio@unipd.it. -FAU - Marcolongo, Renzo -AU - Marcolongo R -FAU - Jahns, Roland -AU - Jahns R -FAU - Fu, Michael -AU - Fu M -FAU - Felix, Stephan B -AU - Felix SB -FAU - Iliceto, S -AU - Iliceto S -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) -RN - 0 (Autoantibodies) -RN - 0 (Immunosuppressive Agents) -SB - IM -MH - Anti-Inflammatory Agents, Non-Steroidal/therapeutic use -MH - Autoantibodies/immunology -MH - Autoimmune Diseases/diagnosis/*therapy -MH - Biopsy, Needle -MH - Blotting, Western/methods -MH - Cardiomyopathy, Dilated/diagnosis/*immunology/*therapy -MH - Combined Modality Therapy -MH - Echocardiography, Doppler -MH - Electrocardiography/methods -MH - Enzyme-Linked Immunosorbent Assay/methods -MH - Female -MH - Heart Transplantation -MH - Humans -MH - Immunohistochemistry -MH - Immunosuppressive Agents/therapeutic use -MH - Magnetic Resonance Imaging, Cine/methods -MH - Male -MH - Myocarditis/diagnosis/*immunology/*therapy -MH - Prognosis -MH - Risk Assessment -EDAT- 2012/11/02 06:00 -MHDA- 2014/07/02 06:00 -CRDT- 2012/11/02 06:00 -PHST- 2012/11/02 06:00 [entrez] -PHST- 2012/11/02 06:00 [pubmed] -PHST- 2014/07/02 06:00 [medline] -AID - 10.1007/s10741-012-9364-5 [doi] -PST - ppublish -SO - Heart Fail Rev. 2013 Nov;18(6):715-32. doi: 10.1007/s10741-012-9364-5. - -PMID- 18220637 -OWN - NLM -STAT- MEDLINE -DCOM- 20080227 -LR - 20191110 -IS - 1573-3998 (Print) -IS - 1573-3998 (Linking) -VI - 2 -IP - 3 -DP - 2006 Aug -TI - Baroreflex function: determinants in healthy subjects and disturbances in - diabetes, obesity and metabolic syndrome. -PG - 329-38 -AB - Arterial baroreceptors play an important role in the short-term regulation of - arterial pressure, by reflex chronotropic effect on the heart and by reflex - regulation of sympathetic outflow. Baroreflex sensitivity (BRS) represents an - index of arterial baroreceptors function. Several methods of measuring BRS are - available nowadays. Different factors influence BRS in the healthy population, - including sex, age, blood pressure, heart rate, body fatness, arterial stiffness, - blood glucose and insulin levels, as well as physical activity. Baroreceptors - dysfunction is evident in diseases such as coronary artery disease, heart - failure, arterial hypertension, diabetes mellitus and obesity. The underlying - mechanism of BRS attenuation in diabetes or obesity is not yet well known; - however, there is increasing evidence that it is at least partly related to - autonomic nervous system dysfunction and particularly to sympathetic overactivity - that accompanies these diseases. Blunted BRS provides prognostic information for - cardiovascular diseases and possibly for diabetes, while its' prognostic - information for obesity is not yet established. This review deals with the - mechanisms affecting baroreflex function, the newer techniques of BRS estimation - and the most recent insights of baroreflex function in the healthy population and - in various diseases with emphasis on diabetes and obesity. In addition, the - clinical implication of a reduced BRS in these disorders is discussed. -FAU - Skrapari, Ioanna -AU - Skrapari I -AD - 1st Department of Propaedeutic Medicine, Athens University Medical School, Laiko - General Hospital, Athens, Greece. -FAU - Tentolouris, Nicholas -AU - Tentolouris N -FAU - Katsilambros, Nicholas -AU - Katsilambros N -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Diabetes Rev -JT - Current diabetes reviews -JID - 101253260 -SB - IM -MH - Adult -MH - Aged -MH - Baroreflex/*physiology -MH - Blood Pressure/physiology -MH - Brain Stem/physiology -MH - Diabetes Mellitus/*physiopathology -MH - Exercise -MH - Female -MH - Heart Rate -MH - Humans -MH - Hypertension/physiopathology -MH - Male -MH - Metabolic Syndrome/*physiopathology -MH - Middle Aged -MH - Models, Biological -MH - Obesity/*physiopathology -MH - Reference Values -RF - 137 -EDAT- 2008/01/29 09:00 -MHDA- 2008/02/28 09:00 -CRDT- 2008/01/29 09:00 -PHST- 2008/01/29 09:00 [pubmed] -PHST- 2008/02/28 09:00 [medline] -PHST- 2008/01/29 09:00 [entrez] -AID - 10.2174/157339906777950589 [doi] -PST - ppublish -SO - Curr Diabetes Rev. 2006 Aug;2(3):329-38. doi: 10.2174/157339906777950589. - -PMID- 22858388 -OWN - NLM -STAT- MEDLINE -DCOM- 20121218 -LR - 20220318 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 60 -IP - 14 -DP - 2012 Oct 2 -TI - Cardiovascular disease in the developing world: prevalences, patterns, and the - potential of early disease detection. -PG - 1207-16 -LID - S0735-1097(12)02068-2 [pii] -LID - 10.1016/j.jacc.2012.03.074 [doi] -AB - Over the past decade or more, the prevalence of traditional risk factors for - atherosclerotic cardiovascular diseases has been increasing in the major populous - countries of the developing world, including China and India, with consequent - increases in the rates of coronary and cerebrovascular events. Indeed, by 2020, - cardiovascular diseases are predicted to be the major causes of morbidity and - mortality in most developing nations around the world. Techniques for the early - detection of arterial damage have provided important insights into disease - patterns and pathogenesis and especially the effects of progressive urbanization - on cardiovascular risk in these populations. Furthermore, certain other diseases - affecting the cardiovascular system remain prevalent and important causes of - cardiovascular morbidity and mortality in developing countries, including the - cardiac effects of rheumatic heart disease and the vascular effects of malaria. - Imaging and functional studies of early cardiovascular changes in those disease - processes have also recently been published by various groups, allowing - consideration of screening and early treatment opportunities. In this report, the - authors review the prevalences and patterns of major cardiovascular diseases in - the developing world, as well as potential opportunities provided by early - disease detection. -CI - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Celermajer, David S -AU - Celermajer DS -AD - The University of Sydney, Sydney, Australia; Department of Cardiology, Royal - Prince Alfred Hospital, Sydney, Australia. david.celermajer@email.cs.nsw.gov.au -FAU - Chow, Clara K -AU - Chow CK -FAU - Marijon, Eloi -AU - Marijon E -FAU - Anstey, Nicholas M -AU - Anstey NM -FAU - Woo, Kam S -AU - Woo KS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120801 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Cardiovascular Diseases/diagnosis/*epidemiology/etiology -MH - China/epidemiology -MH - Developing Countries/*statistics & numerical data -MH - Early Diagnosis -MH - Humans -MH - India/epidemiology -MH - Prevalence -MH - Risk Factors -EDAT- 2012/08/04 06:00 -MHDA- 2012/12/19 06:00 -CRDT- 2012/08/04 06:00 -PHST- 2012/01/31 00:00 [received] -PHST- 2012/02/29 00:00 [revised] -PHST- 2012/03/06 00:00 [accepted] -PHST- 2012/08/04 06:00 [entrez] -PHST- 2012/08/04 06:00 [pubmed] -PHST- 2012/12/19 06:00 [medline] -AID - S0735-1097(12)02068-2 [pii] -AID - 10.1016/j.jacc.2012.03.074 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2012 Oct 2;60(14):1207-16. doi: 10.1016/j.jacc.2012.03.074. - Epub 2012 Aug 1. - -PMID- 22940871 -OWN - NLM -STAT- MEDLINE -DCOM- 20130430 -LR - 20211021 -IS - 1546-9549 (Electronic) -IS - 1546-9530 (Print) -IS - 1546-9530 (Linking) -VI - 9 -IP - 4 -DP - 2012 Dec -TI - Aging of the United States population: impact on heart failure. -PG - 369-74 -LID - 10.1007/s11897-012-0114-8 [doi] -AB - The United States population, particularly among older age groups, continues to - expand. Because the incidence of heart failure increases with age, largely due to - the development of heart failure risk factors such as hypertension and coronary - artery disease, the epidemic of heart failure is likely to grow further in the - coming decades. This article will review the epidemiology of heart failure among - older adults, the influence of an aging population on heart failure prevalence - and phenotype, the complications in management for a larger and older heart - failure population, and the potential implications of these changes for health - care costs and delivery. Ultimately, these challenges demand research into - optimal therapeutic strategies for older heart failure patients, including - improved prevention and treatment of the major causes of heart failure, an - increasing role forpalliative care, and innovations in patient-centered health - care delivery. -FAU - Vigen, Rebecca -AU - Vigen R -AD - Division of Cardiology, University of Colorado School of Medicine, Aurora, CO - 80045, USA. rebecca.vigen@ucdenver.edu -FAU - Maddox, Thomas M -AU - Maddox TM -FAU - Allen, Larry A -AU - Allen LA -LA - eng -GR - K23 HL105896/HL/NHLBI NIH HHS/United States -GR - 1K23HL105896/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Heart Fail Rep -JT - Current heart failure reports -JID - 101196487 -SB - IM -MH - Age Distribution -MH - Age Factors -MH - Aged -MH - Aged, 80 and over -MH - Health Resources/statistics & numerical data -MH - Heart Failure/*epidemiology/etiology/therapy -MH - Humans -MH - Hypertension/complications/epidemiology -MH - Myocardial Ischemia/complications/epidemiology -MH - United States/epidemiology -PMC - PMC3893701 -MID - NIHMS539400 -EDAT- 2012/09/04 06:00 -MHDA- 2013/05/01 06:00 -PMCR- 2014/01/16 -CRDT- 2012/09/04 06:00 -PHST- 2012/09/04 06:00 [entrez] -PHST- 2012/09/04 06:00 [pubmed] -PHST- 2013/05/01 06:00 [medline] -PHST- 2014/01/16 00:00 [pmc-release] -AID - 10.1007/s11897-012-0114-8 [doi] -PST - ppublish -SO - Curr Heart Fail Rep. 2012 Dec;9(4):369-74. doi: 10.1007/s11897-012-0114-8. - -PMID- 21553380 -OWN - NLM -STAT- MEDLINE -DCOM- 20111104 -LR - 20110822 -IS - 1696-3547 (Electronic) -IS - 0214-6282 (Linking) -VI - 55 -IP - 4-5 -DP - 2011 -TI - Cell-based cardiovascular repair and regeneration in acute myocardial infarction - and chronic ischemic cardiomyopathy-current status and future developments. -PG - 407-17 -LID - 10.1387/ijdb.103219ct [doi] -AB - Ischemic heart disease is the main cause of death and morbidity in most - industrialized countries. Stem- and progenitor cell-based treatment approaches - for ischemic heart disease are therefore an important frontier in cardiovascular - and regenerative medicine. Experimental studies have shown that - bone-marrow-derived stem cells and endothelial progenitor cells can improve - cardiac function after myocardial infarction, clinical phase I and II studies - were rapidly initiated to translate this concept into the clinical setting. - However, as of now the effects of stem/progenitor cell administration on cardiac - function in the clinical setting have not met expectations. Thus, a better - understanding of causes of the current limitations of cell-based therapies is - urgently required. Importantly, the number and function of endothelial progenitor - cells is reduced in patients with cardiovascular risk factors and/or coronary - artery disease. These observations may provide opportunities for an optimization - of cell-based treatment approaches. This review provides a summary of current - evidence for the role and potential of stem and progenitor cells in the - pathophysiology and treatment of ischemic heart disease, including the - properties, and repair and regenerative capacities of various stem and progenitor - cell populations. In addition, we describe modes of stem/progenitor cell - delivery, modulation of their homing as well as potential approaches to "prime" - stem/progenitor cells for cardiovascular cell-based therapies. -FAU - Templin, Christian -AU - Templin C -AD - Department of Cardiology, University Hospital Zurich and Cardiovascular Research, - Switzerland. Christian.Templin@usz.ch -FAU - Lüscher, Thomas F -AU - Lüscher TF -FAU - Landmesser, Ulf -AU - Landmesser U -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Spain -TA - Int J Dev Biol -JT - The International journal of developmental biology -JID - 8917470 -SB - IM -MH - Adult Stem Cells/transplantation -MH - Animals -MH - Clinical Trials as Topic -MH - Humans -MH - Myocardial Infarction/pathology/physiopathology/*therapy -MH - Myocardial Ischemia/pathology/physiopathology/*therapy -MH - Regeneration -MH - Stem Cell Transplantation/*methods/trends -EDAT- 2011/05/10 06:00 -MHDA- 2011/11/05 06:00 -CRDT- 2011/05/10 06:00 -PHST- 2011/05/10 06:00 [entrez] -PHST- 2011/05/10 06:00 [pubmed] -PHST- 2011/11/05 06:00 [medline] -AID - 103219ct [pii] -AID - 10.1387/ijdb.103219ct [doi] -PST - ppublish -SO - Int J Dev Biol. 2011;55(4-5):407-17. doi: 10.1387/ijdb.103219ct. - -PMID- 24022031 -OWN - NLM -STAT- MEDLINE -DCOM- 20150219 -LR - 20131217 -IS - 1879-016X (Electronic) -IS - 0163-7258 (Linking) -VI - 141 -IP - 1 -DP - 2014 Jan -TI - Statins in heart failure--With preserved and reduced ejection fraction. An - update. -PG - 79-91 -LID - S0163-7258(13)00182-4 [pii] -LID - 10.1016/j.pharmthera.2013.09.001 [doi] -AB - HMG-CoA reductase inhibitors or statins beyond their lipid lowering properties - and mevalonate inhibition exert also their actions through a multiplicity of - mechanisms. In heart failure (HF) the inhibition of isoprenoid intermediates and - small GTPases, which control cellular function such as cell shape, secretion and - proliferation, is of clinical significance. Statins share also the peroxisome - proliferator-activated receptor pathway and inactivate - extracellular-signal-regulated kinase phosphorylation suppressing inflammatory - cascade. By down-regulating Rho/Rho kinase signaling pathways, statins increase - the stability of eNOS mRNA and induce activation of eNOS through - phosphatidylinositol 3-kinase/Akt/eNOS pathway restoring endothelial function. - Statins change also myocardial action potential plateau by modulation of Kv1.5 - and Kv4.3 channel activity and inhibit sympathetic nerve activity suppressing - arrhythmogenesis. Less documented evidence proposes also that statins have - anti-hypertrophic effects - through p21ras/mitogen activated protein kinase - pathway - which modulate synthesis of matrix metalloproteinases and procollagen 1 - expression affecting interstitial fibrosis and diastolic dysfunction. Clinical - studies have partly confirmed the experimental findings and despite current - guidelines new evidence supports the notion that statins can be beneficial in - some cases of HF. In subjects with diastolic HF, moderately impaired systolic - function, low b-type natriuretic peptide levels, exacerbated inflammatory - response and mild interstitial fibrosis evidence supports that statins can - favorably affect the outcome. Under the lights of this evidence in this review - article we discuss the current knowledge on the mechanisms of statins' actions - and we link current experimental and clinical data to further understand the - possible impact of statins' treatment on HF syndrome. -CI - © 2013. -FAU - Tousoulis, Dimitris -AU - Tousoulis D -AD - 1st Cardiology Department, University of Athens Medical School, "Hippokration" - Hospital, Athens, Greece. Electronic address: drtousoulis@hotmail.com. -FAU - Oikonomou, Evangelos -AU - Oikonomou E -AD - 1st Cardiology Department, University of Athens Medical School, "Hippokration" - Hospital, Athens, Greece. -FAU - Siasos, Gerasimos -AU - Siasos G -AD - 1st Cardiology Department, University of Athens Medical School, "Hippokration" - Hospital, Athens, Greece. -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -AD - 1st Cardiology Department, University of Athens Medical School, "Hippokration" - Hospital, Athens, Greece. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130908 -PL - England -TA - Pharmacol Ther -JT - Pharmacology & therapeutics -JID - 7905840 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Heart/drug effects/physiology -MH - Heart Failure/*drug therapy/metabolism/*physiopathology -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology/*therapeutic use -MH - Myocardium/metabolism -MH - Signal Transduction/*drug effects -MH - Stroke Volume/*drug effects/*physiology -OTO - NOTNLM -OT - C reactive protein -OT - CAD -OT - CRP -OT - Diastolic function -OT - EF -OT - ERK -OT - HF -OT - HMG-CoA reductase inhibitors -OT - Heart failure -OT - IL- -OT - Inflammation -OT - LV -OT - MMPs -OT - Mortality -OT - NADPH -OT - NF-κΒ -OT - NO -OT - PRAP -OT - Statins -OT - TNFα -OT - coronary artery disease -OT - eNOS -OT - ejection fraction -OT - endothelial NO synthase -OT - extracellular-signal-regulated kinase -OT - heart failure -OT - interleukin -OT - left ventricle -OT - matrix metalloproteinases -OT - nicotinamide adenine dinucleotide phosphate -OT - nitric oxide -OT - nuclear factor Kappa B -OT - peroxisome proliferator-activated receptor -OT - tumor necrosis factor alpha -EDAT- 2013/09/12 06:00 -MHDA- 2015/02/20 06:00 -CRDT- 2013/09/12 06:00 -PHST- 2013/08/12 00:00 [received] -PHST- 2013/08/12 00:00 [accepted] -PHST- 2013/09/12 06:00 [entrez] -PHST- 2013/09/12 06:00 [pubmed] -PHST- 2015/02/20 06:00 [medline] -AID - S0163-7258(13)00182-4 [pii] -AID - 10.1016/j.pharmthera.2013.09.001 [doi] -PST - ppublish -SO - Pharmacol Ther. 2014 Jan;141(1):79-91. doi: 10.1016/j.pharmthera.2013.09.001. - Epub 2013 Sep 8. - -PMID- 18208353 -OWN - NLM -STAT- MEDLINE -DCOM- 20080418 -LR - 20181201 -IS - 1431-6730 (Print) -IS - 1431-6730 (Linking) -VI - 389 -IP - 3 -DP - 2008 Mar -TI - Sirt1 protects the heart from aging and stress. -PG - 221-31 -LID - 10.1515/BC.2008.032 [doi] -AB - The prevalence of heart diseases, such as coronary artery disease and congestive - heart failure, increases with age. Optimal therapeutic interventions that - antagonize aging may reduce the occurrence and mortality of adult heart diseases. - We discuss here how molecular mechanisms mediating life span extension affect - aging of the heart and its resistance to pathological insults. In particular, we - review our recent findings obtained from transgenic mice with cardiac-specific - overexpression of Sirt1, which demonstrated delayed aging and protection against - oxidative stress in the heart. We propose that activation of known longevity - mechanisms in the heart may represent a novel cardioprotection strategy against - aging and certain types of cardiac stress, such as oxidative stress. -FAU - Hsu, Chiao-Po -AU - Hsu CP -AD - Cardiovascular Research Institute, Department of Cell Biology and Molecular - Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical - School, Newark, NJ 07103, USA. -FAU - Odewale, Ibrahim -AU - Odewale I -FAU - Alcendor, Ralph R -AU - Alcendor RR -FAU - Sadoshima, Junichi -AU - Sadoshima J -LA - eng -GR - AG23039/AG/NIA NIH HHS/United States -GR - AG28787/AG/NIA NIH HHS/United States -GR - HL 59139/HL/NHLBI NIH HHS/United States -GR - HL67724/HL/NHLBI NIH HHS/United States -GR - HL69020/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Germany -TA - Biol Chem -JT - Biological chemistry -JID - 9700112 -RN - 0 (Stilbenes) -RN - EC 2.4.2.12 (Nicotinamide Phosphoribosyltransferase) -RN - EC 3.5.1.- (SIRT1 protein, human) -RN - EC 3.5.1.- (Sirtuin 1) -RN - EC 3.5.1.- (Sirtuins) -RN - Q369O8926L (Resveratrol) -SB - IM -MH - Aging/*drug effects -MH - Animals -MH - Apoptosis/drug effects -MH - Caloric Restriction -MH - Heart/*drug effects/*physiology -MH - Heart Diseases/*prevention & control -MH - Heart Failure/drug therapy -MH - Humans -MH - Longevity/physiology -MH - Mice -MH - Nicotinamide Phosphoribosyltransferase/metabolism -MH - Oxidative Stress/drug effects -MH - Resveratrol -MH - Saccharomyces cerevisiae/drug effects -MH - Sirtuin 1 -MH - Sirtuins/*physiology -MH - Stilbenes/pharmacology -MH - Up-Regulation -RF - 140 -EDAT- 2008/01/23 09:00 -MHDA- 2008/04/19 09:00 -CRDT- 2008/01/23 09:00 -PHST- 2008/01/23 09:00 [pubmed] -PHST- 2008/04/19 09:00 [medline] -PHST- 2008/01/23 09:00 [entrez] -AID - 10.1515/BC.2008.032 [doi] -PST - ppublish -SO - Biol Chem. 2008 Mar;389(3):221-31. doi: 10.1515/BC.2008.032. - -PMID- 22883347 -OWN - NLM -STAT- MEDLINE -DCOM- 20140226 -LR - 20130723 -IS - 1747-0803 (Electronic) -IS - 1747-079X (Linking) -VI - 8 -IP - 4 -DP - 2013 Jul-Aug -TI - Tetralogy of Fallot with complete DiGeorge syndrome: report of a case and a - review of the literature. -PG - E119-26 -LID - 10.1111/j.1747-0803.2012.00694.x [doi] -AB - Complete DiGeorge syndrome (CDGS) has a severe T-cell immunodeficiency and is - fatal without thymus or bone marrow transplantation. Associated congenital heart - disease (CHD) further complicates the clinical management. We report an infant - with tetralogy of Fallot, confluent and hypoplastic pulmonary arteries, right - aortic arch, and aberrant left subclavian artery. He was athymic with no CD3+ T - cells. CDGS was diagnosed with 22q11.2 deletion. The patient underwent central - aortopulmonary shunt at 12 days of age. The patient died at 5 weeks of age - awaiting thymus transplantation. We performed a review of the literature - regarding CDGS and CHD. We found 43 cases including conotruncal defects (20) and - nonconotruncal defects (23). The overall mortality rate was 67%. Among 30 cases - undergoing transplantation (bone marrow 16 and thymus 12, bone marrow + thymus - 2), the mortality rate was 53%. The patients with conotruncal defects were more - likely to die before transplantation (45% vs. 16%, P =.04). The main cause of - death was infection before and after transplantation. We conclude that children - with CDGS and CHD have a high mortality. Bone marrow and thymus transplantation - can improve the survival, but the overall management of these high risk patients - remains challenging. -CI - © 2012 Wiley Periodicals, Inc. -FAU - Kobayashi, Daisuke -AU - Kobayashi D -AD - Section of Pediatric Cardiology, Children's Hospital of Michigan, Carman and Ann - Adams Department of Pediatrics, Wayne State University School of Medicine, - Detroit, MI 48201-2119, USA. -FAU - Sallaam, Salaam -AU - Sallaam S -FAU - Humes, Richard A -AU - Humes RA -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20120807 -PL - United States -TA - Congenit Heart Dis -JT - Congenital heart disease -JID - 101256510 -SB - IM -MH - Cardiac Surgical Procedures -MH - Coronary Angiography -MH - DiGeorge Syndrome/*complications/diagnosis/genetics/surgery -MH - Fatal Outcome -MH - Humans -MH - Infant, Newborn -MH - Male -MH - Tetralogy of Fallot/*complications/diagnosis/surgery -MH - Thymus Gland/transplantation -MH - Time Factors -MH - Waiting Lists -OTO - NOTNLM -OT - Bone Marrow Transplantation -OT - Complete DiGeorge Syndrome -OT - Congenital Heart Disease -OT - Tetralogy of Fallot -OT - Thymus Transplantation -EDAT- 2012/08/14 06:00 -MHDA- 2014/02/27 06:00 -CRDT- 2012/08/14 06:00 -PHST- 2012/05/30 00:00 [accepted] -PHST- 2012/08/14 06:00 [entrez] -PHST- 2012/08/14 06:00 [pubmed] -PHST- 2014/02/27 06:00 [medline] -AID - 10.1111/j.1747-0803.2012.00694.x [doi] -PST - ppublish -SO - Congenit Heart Dis. 2013 Jul-Aug;8(4):E119-26. doi: - 10.1111/j.1747-0803.2012.00694.x. Epub 2012 Aug 7. - -PMID- 18154959 -OWN - NLM -STAT- MEDLINE -DCOM- 20080107 -LR - 20220408 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 50 -IP - 25 -DP - 2007 Dec 18 -TI - Natriuretic peptides. -PG - 2357-68 -AB - Natriuretic peptides (NPs) are released from the heart in response to pressure - and volume overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have - become important diagnostic tools for assessing patients who present acutely with - dyspnea. The NP level reflects a compilation of systolic and diastolic function - as well as right ventricular and valvular function. Studies suggest that using - NPs in the emergency department can reduce the consumption of hospital resources - and can lower costs by either eliminating the need for other, more expensive - tests or by establishing an alternative diagnosis that does not require hospital - stay. Caveats such as body mass index and renal function must be taken into - account when analyzing NP levels. Natriuretic peptide levels have important - prognostic value in multiple clinical settings, including in patients with stable - coronary artery disease and with acute coronary syndromes. In patients with - decompensated heart failure due to volume overload, a treatment-induced drop in - wedge pressure is often accompanied by a rapid drop in NP levels. Knowing a - patient's NP levels might thus assist with hemodynamic assessment and subsequent - treatment titration. Monitoring NP levels in the outpatient setting might also - improve patient care and outcomes. -FAU - Daniels, Lori B -AU - Daniels LB -AD - Division of Cardiology, University of California at San Diego, and Veteran's - Affairs San Diego Healthcare System, San Diego, California 92037-1300, USA. - loridaniels@ucsd.edu -FAU - Maisel, Alan S -AU - Maisel AS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Peptide Fragments) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - 127869-51-6 (Natriuretic Peptide, C-Type) -RN - 85637-73-6 (Atrial Natriuretic Factor) -SB - IM -MH - Atrial Natriuretic Factor/*blood -MH - Cardiovascular Diseases/blood/*physiopathology/therapy -MH - Death, Sudden, Cardiac/prevention & control -MH - Heart Diseases/diagnosis/physiopathology/therapy -MH - Heart Failure/diagnosis/physiopathology/therapy -MH - Hemodynamics/*physiology -MH - Humans -MH - Kidney Failure, Chronic/diagnosis/physiopathology/therapy -MH - Monitoring, Physiologic -MH - Natriuretic Peptide, Brain/*blood -MH - Natriuretic Peptide, C-Type/*blood -MH - Obesity/physiopathology/therapy -MH - Peptide Fragments/blood -MH - Prognosis -MH - Pulmonary Edema/diagnosis/physiopathology/therapy -MH - Pulmonary Embolism/diagnosis/physiopathology/therapy -MH - Pulmonary Wedge Pressure/physiology -MH - Renal Dialysis -MH - Stroke/diagnosis/physiopathology/therapy -MH - Weight Loss/physiology -RF - 120 -EDAT- 2007/12/25 09:00 -MHDA- 2008/01/08 09:00 -CRDT- 2007/12/25 09:00 -PHST- 2007/07/31 00:00 [received] -PHST- 2007/09/10 00:00 [revised] -PHST- 2007/09/26 00:00 [accepted] -PHST- 2007/12/25 09:00 [pubmed] -PHST- 2008/01/08 09:00 [medline] -PHST- 2007/12/25 09:00 [entrez] -AID - S0735-1097(07)03118-X [pii] -AID - 10.1016/j.jacc.2007.09.021 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2007 Dec 18;50(25):2357-68. doi: 10.1016/j.jacc.2007.09.021. - -PMID- 23829554 -OWN - NLM -STAT- MEDLINE -DCOM- 20130916 -LR - 20130708 -IS - 1470-8736 (Electronic) -IS - 0143-5221 (Linking) -VI - 125 -IP - 9 -DP - 2013 Nov -TI - Mineralocorticoid receptors and the heart, multiple cell types and multiple - mechanisms: a focus on the cardiomyocyte. -PG - 409-21 -LID - 10.1042/CS20130050 [doi] -AB - MR (mineralocorticoid receptor) activation in the heart plays a central role in - the development of cardiovascular disease, including heart failure. The MR is - present in many cell types within the myocardium, including cardiomyocytes, - macrophages and the coronary vasculature. The specific role of the MR in each of - these cell types in the initiation and progression of cardiac pathophysiology is - not fully understood. Cardiomyocyte MRs are increasingly recognized to play a - role in regulating cardiac function, electrical conduction and fibrosis, through - direct signal mediation and through paracrine MR-dependent activity. Although MR - blockade in the heart is an attractive therapeutic option for the treatment of - heart failure and other forms of heart disease, current antagonists are limited - by side effects owing to MR inactivation in other tissues (including renal - targets). This has led to increased efforts to develop therapeutics that are more - selective for cardiac MRs and which may have reduced the occurrence of side - effects in non-cardiac tissues. A major clinical consideration in the treatment - of cardiovascular disease is of the differences between males and females in the - incidence and outcomes of cardiac events. There is clinical evidence that female - sensitivity to endogenous MRs is more pronounced, and experimentally that - MR-targeted interventions may be more efficacious in females. Given that sex - differences have been described in MR signalling in a range of experimental - settings and that the MR and oestrogen receptor pathways share some common - signalling intermediates, it is becoming increasingly apparent that the - mechanisms of MRs need to be evaluated in a sex-selective manner. Further - research targeted to identify sex differences in cardiomyocyte MR activation and - signalling processes has the potential to provide the basis for the development - of cardiac-specific MR therapies that may also be sex-specific. -FAU - Bienvenu, Laura A -AU - Bienvenu LA -AD - Prince Henry's Institute of Medical Research, Clayton, VIC 3168, Australia. -FAU - Reichelt, Melissa E -AU - Reichelt ME -FAU - Delbridge, Lea M D -AU - Delbridge LM -FAU - Young, Morag J -AU - Young MJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Clin Sci (Lond) -JT - Clinical science (London, England : 1979) -JID - 7905731 -RN - 0 (Mineralocorticoid Receptor Antagonists) -RN - 0 (Receptors, Mineralocorticoid) -SB - IM -MH - Animals -MH - Arrhythmias, Cardiac/physiopathology -MH - Cardiovascular Diseases/drug therapy -MH - Female -MH - Fibrosis -MH - Heart Failure/drug therapy -MH - Humans -MH - Macrophages/physiology -MH - Male -MH - Mineralocorticoid Receptor Antagonists/therapeutic use -MH - Myocardial Contraction/physiology -MH - Myocardial Ischemia/physiopathology -MH - Myocardium/metabolism/pathology -MH - Myocytes, Cardiac/*physiology -MH - Oxidative Stress/physiology -MH - Receptors, Mineralocorticoid/*physiology -MH - Sex Factors -MH - Signal Transduction/*physiology -EDAT- 2013/07/09 06:00 -MHDA- 2013/09/17 06:00 -CRDT- 2013/07/09 06:00 -PHST- 2013/07/09 06:00 [entrez] -PHST- 2013/07/09 06:00 [pubmed] -PHST- 2013/09/17 06:00 [medline] -AID - CS20130050 [pii] -AID - 10.1042/CS20130050 [doi] -PST - ppublish -SO - Clin Sci (Lond). 2013 Nov;125(9):409-21. doi: 10.1042/CS20130050. - -PMID- 22737949 -OWN - NLM -STAT- MEDLINE -DCOM- 20120731 -LR - 20181201 -IS - 1660-9379 (Print) -IS - 1660-9379 (Linking) -VI - 8 -IP - 343 -DP - 2012 May 30 -TI - [Management of cardiac failure: a guilty one easy to target!]. -PG - 1154-5, 1157-8 -AB - The proven benefits of beta blockers and angiotensin converting enzyme (ACE) - inhibitors in the treatment of chronic heart failure, could be linked, at least - in part, to their heart-rate-lowering properties. The link between a high heart - rate and cardiovascular morbidity and mortality has been demonstrated in the - general population, as well as in patients with hypertension, coronary artery - disease, and chronic heart failure. Ivabradine is a specific inhibitor of the if - current in the sino-atrial node, without any other known cardiovascular effect, - such as myocardial contraction or intracardiac conduction. The effects of - ivabradine on reducing resting heart-rate, and, therefore, cardiovascular - outcomes have been studied in two large studies: BEAUTIFUL, and, more recently, - SHIFT, both of which are discussed in this article. -FAU - Bieler, Sandra -AU - Bieler S -AD - Service de médecine interne générale, HUG, 121 I Genève 14. - sandra.bieler@hcuge.ch -FAU - Mach, François -AU - Mach F -LA - fre -PT - Journal Article -PT - Review -TT - Prise en charge de l'insuffisance cardiaque: un coupable facile a cerner! -PL - Switzerland -TA - Rev Med Suisse -JT - Revue medicale suisse -JID - 101219148 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Clinical Trials as Topic/methods -MH - Heart Failure/diagnosis/etiology/physiopathology/*therapy -MH - Hospitalization/statistics & numerical data -MH - Humans -MH - Molecular Targeted Therapy/*methods/statistics & numerical data -MH - Treatment Outcome -MH - Ventricular Function, Left/physiology -EDAT- 2012/06/29 06:00 -MHDA- 2012/08/01 06:00 -CRDT- 2012/06/29 06:00 -PHST- 2012/06/29 06:00 [entrez] -PHST- 2012/06/29 06:00 [pubmed] -PHST- 2012/08/01 06:00 [medline] -PST - ppublish -SO - Rev Med Suisse. 2012 May 30;8(343):1154-5, 1157-8. - -PMID- 16685029 -OWN - NLM -STAT- MEDLINE -DCOM- 20060530 -LR - 20220409 -IS - 0012-3692 (Print) -IS - 0012-3692 (Linking) -VI - 129 -IP - 5 -DP - 2006 May -TI - Sepsis-associated myocardial dysfunction: diagnostic and prognostic impact of - cardiac troponins and natriuretic peptides. -PG - 1349-66 -AB - Myocardial dysfunction, which is characterized by transient biventricular - impairment of intrinsic myocardial contractility, is a common complication in - patients with sepsis. Left ventricular systolic dysfunction is reflected by a - reduced left ventricular stroke work index or, less accurately, by an impaired - left ventricular ejection fraction (LVEF). Early recognition of myocardial - dysfunction is crucial for the administration of the most appropriate therapy. - Cardiac troponins and natriuretic peptides are biomarkers that were previously - introduced for diagnosis and risk stratification in patients with acute coronary - syndrome and congestive heart failure, respectively. However, their prognostic - and diagnostic impact in critically ill patients warrants definition. The - elevation of cardiac troponin levels in patients with sepsis, severe sepsis, or - septic shock has been shown to indicate left ventricular dysfunction and a poor - prognosis. Troponin release in this population occurs in the absence of - flow-limiting coronary artery disease, suggesting the presence of mechanisms - other than thrombotic coronary artery occlusion, probably a transient loss in - membrane integrity with subsequent troponin leakage or microvascular thrombotic - injury. In contrast to the rather uniform results of studies dealing with cardiac - troponins, the impact of raised B-type natriuretic peptide (BNP) levels in - patients with sepsis is less clear. The relationship between BNP and both LVEF - and left-sided filling pressures is weak, and data on the prognostic impact of - high BNP levels in patients with sepsis are conflicting. Mechanisms other than - left ventricular wall stress may contribute to BNP release, including right - ventricular overload, catecholamine therapy, renal failure, diseases of the CNS, - and cytokine up-regulation. Whereas cardiac troponins may be integrated into the - monitoring of myocardial dysfunction in patients with severe sepsis or septic - shock to identify those patients requiring early and aggressive supportive - therapy, the routine use of BNP and other natriuretic peptides in this setting is - discouraged at the moment. -FAU - Maeder, Micha -AU - Maeder M -AD - Division of Cardiology, University Hospital, Petersgraben 4, CH-4031 Basel, - Switzerland. micha.maeder@bluewin.ch -FAU - Fehr, Thomas -AU - Fehr T -FAU - Rickli, Hans -AU - Rickli H -FAU - Ammann, Peter -AU - Ammann P -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Chest -JT - Chest -JID - 0231335 -RN - 0 (Biomarkers) -RN - 0 (Natriuretic Peptides) -RN - 0 (Troponin) -SB - IM -MH - Biomarkers/blood -MH - Cardiac Output -MH - Humans -MH - Natriuretic Peptides/*blood -MH - Prognosis -MH - Risk Factors -MH - Sepsis/blood/*complications/diagnosis -MH - Severity of Illness Index -MH - Troponin/*blood -MH - Ventricular Dysfunction, Left/blood/*diagnosis/etiology -RF - 105 -EDAT- 2006/05/11 09:00 -MHDA- 2006/05/31 09:00 -CRDT- 2006/05/11 09:00 -PHST- 2006/05/11 09:00 [pubmed] -PHST- 2006/05/31 09:00 [medline] -PHST- 2006/05/11 09:00 [entrez] -AID - S0012-3692(15)50717-4 [pii] -AID - 10.1378/chest.129.5.1349 [doi] -PST - ppublish -SO - Chest. 2006 May;129(5):1349-66. doi: 10.1378/chest.129.5.1349. - -PMID- 18464680 -OWN - NLM -STAT- MEDLINE -DCOM- 20080617 -LR - 20161021 -IS - 1732-2693 (Electronic) -IS - 0032-5449 (Linking) -VI - 62 -DP - 2008 May 8 -TI - [Function of cannabinoids in heart failure]. -PG - 174-84 -AB - Cannabinoids, substances derived from Cannabis sativa, have been used by humans - as therapeutic agents for thousands of years. They act through the cannabinoid - CB(1), CB(2), vanilloid TRPV1, and the as yet undefined putative endothelial - cannabinoid receptors. Intensive research on the influence of cannabinoids on the - cardiovascular system has been conducted since the 1990s after the discovery that - cannabinoids are involved in hypotension connected with septic, cardiogenic, and - hemorrhagic shock. One cannot exclude the future possibility of using - cannabinoids as new therapeutic agents in diseases of the cardiovascular system. - In the present paper the mechanisms of cannabinoids on heart failure are - described. In the acute phase of myocardial infarction, cannabinoids protect the - endothelium of coronary vessels and decrease the heart's necrotic area and the - risk of arrhythmia. Cannabinoids also act in the chronic phase of myocardial - infarction in the process of the heart remodeling. However, the present knowledge - of the effects of cannabinoids on the acute and chronic phases of myocardial - infarction and the possibility of using these agents in cardiovascular disease - therapy is still insufficient. -FAU - Rudź, Radosław -AU - Rudź R -AD - Zakład Fizjologii Doświadczalnej Uniwersytetu Medycznego w Białymstoku. - rrudz@mail.amb.edu.pl -FAU - Baranowska, Urszula -AU - Baranowska U -FAU - Malinowska, Barbara -AU - Malinowska B -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Znaczenie kannabinoidów w niewydolności serca. -DEP - 20080508 -PL - Poland -TA - Postepy Hig Med Dosw (Online) -JT - Postepy higieny i medycyny doswiadczalnej (Online) -JID - 101206517 -RN - 0 (Cannabinoids) -RN - 0 (Receptor, Cannabinoid, CB1) -RN - 0 (Receptor, Cannabinoid, CB2) -SB - IM -MH - Cannabinoids/*pharmacology/therapeutic use -MH - Endothelium, Vascular/*drug effects -MH - Heart Failure/*drug therapy -MH - Humans -MH - Receptor, Cannabinoid, CB1/drug effects -MH - Receptor, Cannabinoid, CB2/drug effects -MH - Ventricular Remodeling/*drug effects -RF - 85 -EDAT- 2008/05/10 09:00 -MHDA- 2008/06/18 09:00 -CRDT- 2008/05/10 09:00 -PHST- 2007/10/23 00:00 [received] -PHST- 2008/04/02 00:00 [accepted] -PHST- 2008/05/10 09:00 [pubmed] -PHST- 2008/06/18 09:00 [medline] -PHST- 2008/05/10 09:00 [entrez] -AID - 856842 [pii] -PST - epublish -SO - Postepy Hig Med Dosw (Online). 2008 May 8;62:174-84. - -PMID- 17239703 -OWN - NLM -STAT- MEDLINE -DCOM- 20070301 -LR - 20071115 -IS - 0002-9149 (Print) -IS - 0002-9149 (Linking) -VI - 99 -IP - 2A -DP - 2007 Jan 22 -TI - Review of current and investigational pharmacologic agents for acute heart - failure syndromes. -PG - 4A-23A -AB - Acute heart failure syndromes (AHFS) are a major public health problem and - present a therapeutic challenge to clinicians. Commonly used agents in the - treatment of AHFS include diuretics, vasodilators (eg, nitroglycerin, - nitroprusside, nesiritide), and inotropes (eg, dobutamine, dopamine, milrinone). - Patients admitted to hospital with AHFS and low cardiac output state (AHFS/LO) - represent a subgroup with very high inhospital and postdischarge mortality rates. - Most of these patients require intravenous inotropic therapy. However, the use of - current intravenous inotropes has been associated with risk for hypotension, - atrial and ventricular arrhythmias, and possibly increased postdischarge - mortality, particularly in those with coronary artery disease. Consequently, - there is an unmet need for new agents to safely improve cardiac performance - (contractility and/or active relaxation) in this patient population. This article - reviews a selection of current and investigational agents for the treatment of - AHFS, with a main focus on the high-risk patient population with AHFS/LO. -FAU - Shin, David D -AU - Shin DD -AD - Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, - USA, and Division of Cardiology, European Hospital, Rome, Italy. -FAU - Brandimarte, Filippo -AU - Brandimarte F -FAU - De Luca, Leonardo -AU - De Luca L -FAU - Sabbah, Hani N -AU - Sabbah HN -FAU - Fonarow, Gregg C -AU - Fonarow GC -FAU - Filippatos, Gerasimos -AU - Filippatos G -FAU - Komajda, Michel -AU - Komajda M -FAU - Gheorghiade, Mihai -AU - Gheorghiade M -LA - eng -PT - Journal Article -PT - Review -DEP - 20061127 -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Aged -MH - Blood Pressure/drug effects -MH - Cardiac Output, Low/*drug therapy/mortality -MH - Cardiotonic Agents/adverse effects/*therapeutic use -MH - Female -MH - Heart Failure/*drug therapy/mortality -MH - Hospitalization -MH - Humans -MH - Male -MH - Randomized Controlled Trials as Topic -MH - Registries -MH - Syndrome -RF - 170 -EDAT- 2007/01/24 09:00 -MHDA- 2007/03/03 09:00 -CRDT- 2007/01/24 09:00 -PHST- 2007/01/24 09:00 [pubmed] -PHST- 2007/03/03 09:00 [medline] -PHST- 2007/01/24 09:00 [entrez] -AID - S0002-9149(06)02243-0 [pii] -AID - 10.1016/j.amjcard.2006.11.025 [doi] -PST - ppublish -SO - Am J Cardiol. 2007 Jan 22;99(2A):4A-23A. doi: 10.1016/j.amjcard.2006.11.025. Epub - 2006 Nov 27. - -PMID- 22159935 -OWN - NLM -STAT- MEDLINE -DCOM- 20120417 -LR - 20111214 -IS - 2737-5935 (Electronic) -IS - 0037-5675 (Linking) -VI - 52 -IP - 12 -DP - 2011 Dec -TI - Incidental cardiac abnormalities on non-electrocardiogram-gated multi-detector - computed tomography imaging of the thorax and abdomen. -PG - 906-12; quiz 913 -AB - Little attention is usually paid to the heart on non-electrocardiogram - (ECG)-gated multi-detector computed tomography (MDCT) imaging of the thorax and - abdomen. The current MDCT systems have fast scanning capabilities that render - non-ECG-gated images with reduced cardiac motion artefacts due to greater - temporal and spatial resolution. This has allowed for better evaluation of the - cardiac structures. We present a pictorial review of incidental cardiac - abnormalities found on MDCT imaging of the thorax and abdomen performed in our - institution. We systematically describe abnormalities involving the pericardium, - myocardium, cardiac valves, cardiac chambers, coronary artery and congenital - heart disease. Some of these images have echocardiograph and magnetic resonance - imaging correlation. The purpose of this pictorial essay is to draw attention to - cardiac abnormalities found incidentally on non-ECG-gated MDCT imaging of the - thorax and abdomen, which may or may not be related to the patient's symptoms. -FAU - Lim, K C -AU - Lim KC -AD - Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent - Ridge Road, Singapore 119074. lynette_ls_teo@nuhs.edu.sg -FAU - Chai, P -AU - Chai P -FAU - Teo, L S -AU - Teo LS -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Singapore Med J -JT - Singapore medical journal -JID - 0404516 -SB - IM -MH - Adult -MH - Aged, 80 and over -MH - Electrocardiography/*methods -MH - Female -MH - Heart Defects, Congenital/pathology -MH - Humans -MH - Magnetic Resonance Imaging/methods -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/pathology -MH - Neoplasms/complications -MH - Pericardial Effusion/pathology -MH - Pericardium/pathology -MH - Radiography, Abdominal/methods -MH - Radiography, Thoracic/methods -MH - Tomography, X-Ray Computed/*methods -EDAT- 2011/12/14 06:00 -MHDA- 2012/04/18 06:00 -CRDT- 2011/12/14 06:00 -PHST- 2011/12/14 06:00 [entrez] -PHST- 2011/12/14 06:00 [pubmed] -PHST- 2012/04/18 06:00 [medline] -PST - ppublish -SO - Singapore Med J. 2011 Dec;52(12):906-12; quiz 913. - -PMID- 21215474 -OWN - NLM -STAT- MEDLINE -DCOM- 20120131 -LR - 20111004 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 152 -IP - 1 -DP - 2011 Oct 6 -TI - Management of hypertension in liver transplant patients. -PG - 4-6 -LID - 10.1016/j.ijcard.2010.12.021 [doi] -AB - Hypertension is a common co-morbidity and a frequent complication in liver - transplant patients. The aim of this paper is to concisely review available - clinical data and propose a hypertension treatment algorithm in liver transplant - patients. Calcium channel blockers are mainstay of the treatment due to their - potent vasodilatory effects. Dihydropyridine calcium channel blockers are - preferable due to their least interaction with cytochrome P450 enzyme system and, - therefore, minimal risk of potential disruption of immunosuppressive drug levels. - Beta-blockers may be considered first line drugs in patients with resting - tachycardia and in those with high cardiac outputs. Data support the use of - beta-blockers for patients intolerant or unresponsive to calcium channel - blockers. Angiotensin converting enzyme inhibitors and angiotensin receptor - blockers have little value when used early after liver transplant but may have a - more pronounced role during the later periods. Diuretics may be of value in - combination with other drugs, especially to counteract the potassium-retaining - effects of calcineurin inhibitors. Treatment of post liver transplantation - hypertension in patients with co-morbid conditions such as coronary artery - disease, diabetes mellitus, congestive heart failure, and renal disease will - likely require combination therapy. -CI - Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. -FAU - Najeed, Syed A -AU - Najeed SA -AD - Dayton VA Medical Center, Dayton, OH, USA. -FAU - Saghir, Syed -AU - Saghir S -FAU - Hein, Brad -AU - Hein B -FAU - Neff, Guy -AU - Neff G -FAU - Shaheen, Mazen -AU - Shaheen M -FAU - Ijaz, Hina -AU - Ijaz H -FAU - Khan, Ijaz A -AU - Khan IA -LA - eng -PT - Journal Article -PT - Review -DEP - 20110106 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Antihypertensive Agents/*therapeutic use -MH - Humans -MH - Hypertension/*drug therapy -MH - *Liver Transplantation -MH - Postoperative Complications/*drug therapy -EDAT- 2011/01/11 06:00 -MHDA- 2012/02/01 06:00 -CRDT- 2011/01/11 06:00 -PHST- 2010/10/12 00:00 [received] -PHST- 2010/12/04 00:00 [accepted] -PHST- 2011/01/11 06:00 [entrez] -PHST- 2011/01/11 06:00 [pubmed] -PHST- 2012/02/01 06:00 [medline] -AID - S0167-5273(10)01062-4 [pii] -AID - 10.1016/j.ijcard.2010.12.021 [doi] -PST - ppublish -SO - Int J Cardiol. 2011 Oct 6;152(1):4-6. doi: 10.1016/j.ijcard.2010.12.021. Epub - 2011 Jan 6. - -PMID- 24003668 -OWN - NLM -STAT- MEDLINE -DCOM- 20131216 -LR - 20130905 -IS - 0033-2240 (Print) -IS - 0033-2240 (Linking) -VI - 70 -IP - 3 -DP - 2013 -TI - [The role of microRNA in ischemic diseases--impact on the regulation of - inflammatory, apoptosis and angiogenesis processes]. -PG - 135-42 -AB - Ischemic diseases, including coronary artery disease and critical limb ischemia, - are one of the leading causes of mortality worldwide. The result of tissue - hypoxia is activation of processes such as inflammatory, angiogenesis and cell - death by apoptosis, autophagy or necrosis. Recenty special attention has been - paid to the investigation of the microRNA's role in these processes. MicroRNAs - (miRNAs) belong to a group of noncoding small RNAs with a length of 20-24 - ribonucleotides, which play an important role in post-transcriptional regulation - of gene expression. Most of them specifically recognizes the 3'-untranslated - regions (UTR) of their target mRNAs, thereby blocking the process of protein - translation or causing mRNA degradation. The purpose of this study was to - describe the role of miRNA in processes of apoptosis, angiogenesis and - inflammation during tissue ischemia. Particular attention was paid to the - regulation of these molecules in cardiac cells, vascular smooth muscle and heart, - and endothelium. In summary diagnostic and therapeutic use of microRNAs in - ischemic disease was discussed. -FAU - Baczyńska, Dagmara -AU - Baczyńska D -AD - Wrovasc--Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital - Specjalistyczny we Wrocławiu, Ośrodek Badawczo-Rozwojowy. - dagmara.baczynska@am.wroc.pl -FAU - Michałowska, Dagmara -AU - Michałowska D -FAU - Witkiewicz, Wojciech -AU - Witkiewicz W -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Rola mikroRNA w chorobach niedokrwiennych--wpływ na regulacje procesów zapalnych, - apoptozy i angiogenezy. -PL - Poland -TA - Przegl Lek -JT - Przeglad lekarski -JID - 19840720R -RN - 0 (MicroRNAs) -SB - IM -MH - Animals -MH - Apoptosis/*genetics -MH - Gene Expression Regulation/genetics -MH - Humans -MH - Inflammation/*genetics -MH - Ischemia/*genetics -MH - MicroRNAs/*genetics -MH - Neovascularization, Pathologic/*genetics -EDAT- 2013/09/06 06:00 -MHDA- 2013/12/18 06:00 -CRDT- 2013/09/06 06:00 -PHST- 2013/09/06 06:00 [entrez] -PHST- 2013/09/06 06:00 [pubmed] -PHST- 2013/12/18 06:00 [medline] -PST - ppublish -SO - Przegl Lek. 2013;70(3):135-42. - -PMID- 22279116 -OWN - NLM -STAT- MEDLINE -DCOM- 20120724 -LR - 20211021 -IS - 1569-9285 (Electronic) -IS - 1569-9293 (Print) -IS - 1569-9285 (Linking) -VI - 14 -IP - 4 -DP - 2012 Apr -TI - Is cardiac magnetic resonance imaging assessment of myocardial viability useful - for predicting which patients with impaired ventricles might benefit from - revascularization? -PG - 395-8 -LID - 10.1093/icvts/ivr161 [doi] -AB - A best evidence topic in cardiac magnetic resonance imaging (MRI) was written - according to a structured protocol. The question addressed was: what is the role - of cardiac magnetic resonance (CMR) imaging in viability assessment of ischaemic - cardiomyopathy? Altogether more than 164 papers were found using the reported - search; of which, 6 represented the best available evidence to answer the - clinical question and an additional 4 were found by crosschecking the reference - lists for further 'best available evidence' papers. The authors, journal, date - and country of publication, patient group studied, study type, relevant outcomes - and results of these papers are tabulated. Using late-gadolinium - enhancement-cardiac magnetic resonance (LGE-CMR) imaging, infarcted myocardium - can be identified by the presence of hyperenhanced signal. The extent of - myocardial hyperenhancement correlates inversely with improved myocardial - contractility following surgical or percutaneous revascularization. Furthermore, - CMR is able to assess not only viability, but also make gold-standard assessment - of ventricular function and volume as well as identify stress perfusion deficits, - each of which is relevant to estimating patient prognosis. National bodies have - also begun to formally recommend CMR imaging for cardiac viability assessment. - For example, the Canadian Cardiovascular Society (CCS) has stated that - 'assessment of myocardial viability in patients with left ventricle dysfunction - or akinetic segments for predicting recovery of ventricular function following - revascularization is a class I indication for the use of LGE-CMR'. We conclude - that cardiac MRI is an excellent tool for predicting myocardial viability, in the - context of acute and chronic ischaemic heart disease whether subsequent - revascularization is achieved by surgical or percutaneous means. In addition, the - versatility of CMR imaging makes it an increasingly attractive tool for the - complete assessment of the patient with ischaemic cardiomyopathy. -FAU - Child, Nicholas M -AU - Child NM -AD - Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK. - nicholaschild@doctors.org.uk -FAU - Das, Rajiv -AU - Das R -LA - eng -PT - Journal Article -PT - Review -DEP - 20120125 -PL - England -TA - Interact Cardiovasc Thorac Surg -JT - Interactive cardiovascular and thoracic surgery -JID - 101158399 -RN - 0 (Contrast Media) -SB - IM -MH - Angioplasty, Balloon, Coronary -MH - Animals -MH - Benchmarking -MH - Contrast Media -MH - Coronary Artery Bypass -MH - Evidence-Based Medicine -MH - Humans -MH - *Magnetic Resonance Imaging -MH - Myocardial Contraction -MH - Myocardial Ischemia/*diagnosis/pathology/physiopathology/therapy -MH - Myocardium/*pathology -MH - Patient Selection -MH - Predictive Value of Tests -MH - Recovery of Function -MH - Tissue Survival -MH - Treatment Outcome -MH - Ventricular Dysfunction, Left/*diagnosis/pathology/physiopathology/therapy -MH - *Ventricular Function, Left -PMC - PMC3309832 -EDAT- 2012/01/27 06:00 -MHDA- 2012/07/25 06:00 -PMCR- 2013/04/01 -CRDT- 2012/01/27 06:00 -PHST- 2012/01/27 06:00 [entrez] -PHST- 2012/01/27 06:00 [pubmed] -PHST- 2012/07/25 06:00 [medline] -PHST- 2013/04/01 00:00 [pmc-release] -AID - ivr161 [pii] -AID - 10.1093/icvts/ivr161 [doi] -PST - ppublish -SO - Interact Cardiovasc Thorac Surg. 2012 Apr;14(4):395-8. doi: 10.1093/icvts/ivr161. - Epub 2012 Jan 25. - -PMID- 16513906 -OWN - NLM -STAT- MEDLINE -DCOM- 20060818 -LR - 20191109 -IS - 1557-2625 (Print) -IS - 1557-2625 (Linking) -VI - 19 -IP - 2 -DP - 2006 Mar-Apr -TI - Can natriuretic peptide levels predict the cardiovascular complications of COX-2 - inhibitors and nonsteroidal anti-inflammatory drugs? -PG - 178-82 -AB - There is evidence that fluid retention, whether due to a disease process or due - to a medication, is associated with a number of cardiovascular diseases, - including heart failure, strokes, coronary artery disease, and cardiovascular - death. There is additional evidence that fluid retention that manifests as - increased intravascular volume adversely affects cardiovascular outcomes. Because - natriuretic peptide levels reflect intravascular volume and pressure, it is - hypothesized that when patients are prescribed medications that promote fluid - retention--such as non-selective nonsteroidal anti-inflammatory drugs and - cyclooxygenase-2 inhibitors--monitoring natriuretic peptide levels before and - after initiating the medication may allow these medications to be used more - safely. -FAU - Blankfield, Robert P -AU - Blankfield RP -AD - Department of Family Medicine, Case Western Reserve University School of - Medicine, Berea, OH, USA. blankfield@adelphia.net -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Am Board Fam Med -JT - Journal of the American Board of Family Medicine : JABFM -JID - 101256526 -RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) -RN - 0 (Biomarkers) -RN - 0 (Cyclooxygenase 2 Inhibitors) -RN - 0 (Natriuretic Peptides) -SB - IM -MH - Anti-Inflammatory Agents, Non-Steroidal/*adverse effects -MH - Biomarkers/blood -MH - Cardiovascular Diseases/chemically induced/*prevention & control -MH - Cyclooxygenase 2 Inhibitors/*adverse effects -MH - Drug Monitoring/*methods -MH - Humans -MH - Natriuretic Peptides/*blood -RF - 68 -EDAT- 2006/03/04 09:00 -MHDA- 2006/08/19 09:00 -CRDT- 2006/03/04 09:00 -PHST- 2006/03/04 09:00 [pubmed] -PHST- 2006/08/19 09:00 [medline] -PHST- 2006/03/04 09:00 [entrez] -AID - 19/2/178 [pii] -AID - 10.3122/jabfm.19.2.178 [doi] -PST - ppublish -SO - J Am Board Fam Med. 2006 Mar-Apr;19(2):178-82. doi: 10.3122/jabfm.19.2.178. - -PMID- 24307101 -OWN - NLM -STAT- MEDLINE -DCOM- 20140821 -LR - 20220311 -IS - 1573-4919 (Electronic) -IS - 0300-8177 (Linking) -VI - 386 -IP - 1-2 -DP - 2014 Jan -TI - Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular - endothelial dysfunction, reactive oxygen species, and mitochondria. -PG - 233-49 -LID - 10.1007/s11010-013-1861-x [doi] -AB - Diabetic cardiomyopathy and heart failure have been recognized as the leading - causes of mortality among diabetics. Diabetic cardiomyopathy has been - characterized primarily by the manifestation of left ventricular dysfunction that - is independent of coronary artery disease and hypertension among the patients - affected by diabetes mellitus. A complex array of contributing factors including - the hypertrophy of left ventricle, alterations of metabolism, microvascular - pathology, insulin resistance, fibrosis, apoptotic cell death, and oxidative - stress have been implicated in the pathogenesis of diabetic cardiomyopathy. - Nevertheless, the exact mechanisms underlying the pathogenesis of diabetic - cardiomyopathy are yet to be established. The critical involvement of - multifarious factors including the vascular endothelial dysfunction, - microangiopathy, reactive oxygen species (ROS), oxidative stress, mitochondrial - dysfunction has been identified in the mechanism of pathogenesis of diabetic - cardiomyopathy. Although it is difficult to establish how each factor contributes - to disease, the involvement of ROS and mitochondrial dysfunction are emerging as - front-runners in the mechanism of pathogenesis of diabetic cardiomyopathy. This - review highlights the role of vascular endothelial dysfunction, ROS, oxidative - stress, and mitochondriopathy in the pathogenesis of diabetic cardiomyopathy. - Furthermore, the review emphasizes that the puzzle has to be solved to firmly - establish the mitochondrial and/or ROS mechanism(s) by identifying their most - critical molecular players involved at both spatial and temporal levels in - diabetic cardiomyopathy as targets for specific and effective - pharmacological/therapeutic interventions. -FAU - Joshi, Mandip -AU - Joshi M -AD - Department of Surgery, University of Connecticut Health Center, Farmington - Avenue, Farmington, CT, 06032, USA. -FAU - Kotha, Sainath R -AU - Kotha SR -FAU - Malireddy, Smitha -AU - Malireddy S -FAU - Selvaraju, Vaithinathan -AU - Selvaraju V -FAU - Satoskar, Abhay R -AU - Satoskar AR -FAU - Palesty, Alexender -AU - Palesty A -FAU - McFadden, David W -AU - McFadden DW -FAU - Parinandi, Narasimham L -AU - Parinandi NL -FAU - Maulik, Nilanjana -AU - Maulik N -LA - eng -GR - HL-56803/HL/NHLBI NIH HHS/United States -GR - HL-69910/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20131204 -PL - Netherlands -TA - Mol Cell Biochem -JT - Molecular and cellular biochemistry -JID - 0364456 -RN - 0 (Reactive Oxygen Species) -SB - IM -MH - Diabetic Cardiomyopathies/*etiology/metabolism -MH - Endothelium, Vascular/*physiopathology -MH - Humans -MH - Mitochondria, Heart/*metabolism -MH - Reactive Oxygen Species/*metabolism -EDAT- 2013/12/07 06:00 -MHDA- 2014/08/22 06:00 -CRDT- 2013/12/06 06:00 -PHST- 2013/07/22 00:00 [received] -PHST- 2013/10/09 00:00 [accepted] -PHST- 2013/12/06 06:00 [entrez] -PHST- 2013/12/07 06:00 [pubmed] -PHST- 2014/08/22 06:00 [medline] -AID - 10.1007/s11010-013-1861-x [doi] -PST - ppublish -SO - Mol Cell Biochem. 2014 Jan;386(1-2):233-49. doi: 10.1007/s11010-013-1861-x. Epub - 2013 Dec 4. - -PMID- 21983316 -OWN - NLM -STAT- MEDLINE -DCOM- 20120208 -LR - 20220409 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 19 -IP - 6 -DP - 2011 Nov-Dec -TI - Obstructive sleep apnea and cardiovascular disease. -PG - 279-90 -LID - 10.1097/CRD.0b013e318223bd08 [doi] -AB - Obstructive sleep apnea (OSA) is a sleep-disordered breathing condition, which is - increasingly being recognized as having wide-ranging pathophysiological effects - on multiple organ systems. Although multiple factors affect the incidence and - severity of OSA, male sex and obesity seem to play an influential role. The - apnea-ventilation cycle, characterized by abnormalities in gas exchange, - exaggerated respiratory effort and frequent arousals, has been shown to have - deleterious effects on circulatory hemodynamics, the autonomic milieu, hormonal - balance, inflammatory and coagulation cascades, endothelial function, and the - redox state, with potential cardiovascular significance. Consequently, OSA is - being increasingly implicated in a multitude of cardiovascular diseases (CVD) - such as hypertension, congestive heart failure, atrial fibrillation, stroke, - coronary artery disease, pulmonary hypertension, and metabolic syndrome. The - strength of association for individual CVD is varied, and outcomes of clinical - studies are conflicting. In addition, obesity, which is closely linked to both - OSA and CVD, makes it harder to ascertain the independent role of OSA on CVD. - Although available evidence is inconclusive, there is an increasing recognition - of the direct role for OSA in CVD. Similarly, although several studies have - demonstrated the cardiovascular benefits of OSA treatment, further studies are - needed to confirm this. -FAU - Gopalakrishnan, Prabhakaran -AU - Gopalakrishnan P -AD - Department of Medicine, JPS Health Network, Fort Worth, TX, USA. -FAU - Tak, Tahir -AU - Tak T -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -SB - IM -MH - Cardiovascular Diseases/*etiology -MH - Humans -MH - Sleep Apnea, Obstructive/*complications/epidemiology/physiopathology/therapy -EDAT- 2011/10/11 06:00 -MHDA- 2012/02/09 06:00 -CRDT- 2011/10/11 06:00 -PHST- 2011/10/11 06:00 [entrez] -PHST- 2011/10/11 06:00 [pubmed] -PHST- 2012/02/09 06:00 [medline] -AID - 00045415-201111000-00004 [pii] -AID - 10.1097/CRD.0b013e318223bd08 [doi] -PST - ppublish -SO - Cardiol Rev. 2011 Nov-Dec;19(6):279-90. doi: 10.1097/CRD.0b013e318223bd08. - -PMID- 18687238 -OWN - NLM -STAT- MEDLINE -DCOM- 20080902 -LR - 20080808 -IS - 1533-7294 (Electronic) -IS - 0094-3509 (Linking) -VI - 57 -IP - 8 Suppl -DP - 2008 Aug -TI - The clinical consequences of obstructive sleep apnea and associated excessive - sleepiness. -PG - S9-16 -AB - Several conditions commonly seen in the primary care setting are known to be - associated with obstructive sleep apnea (OSA), including hypertension, obesity, - coronary artery disease, and type 2 diabetes, and should alert the physician to - the possibility of this sleep disorder. The pathophysiology of OSA increases the - risk of ischemic heart disease, decreases cardiac function, and elevates the risk - of stroke. Treatment of OSA along with appropriate therapy for associated - comorbidities presents an opportunity to simultaneously improve both conditions. - Up to 56% of patients with OSA have hypertension. Addressing OSA can help improve - this condition. More than 50% of patients with OSA experience depression. - Treatment of OSA can lessen depressive symptoms associated with this sleeping - disorder. -FAU - Hirshkowitz, Max -AU - Hirshkowitz M -AD - Department of Medicine and Menninger Department of Psychiatry, Baylor College of - Medicine, Houston, USA. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Fam Pract -JT - The Journal of family practice -JID - 7502590 -SB - IM -MH - Cardiovascular Diseases/*etiology -MH - Diabetes Mellitus, Type 2/*etiology -MH - Humans -MH - Hypertension/*etiology -MH - Obesity/*etiology -MH - *Positive-Pressure Respiration -MH - Risk Factors -MH - *Sleep Apnea, Obstructive/complications/physiopathology/therapy -MH - Stress, Psychological/etiology -RF - 78 -EDAT- 2008/08/21 09:00 -MHDA- 2008/09/03 09:00 -CRDT- 2008/08/21 09:00 -PHST- 2008/08/21 09:00 [pubmed] -PHST- 2008/09/03 09:00 [medline] -PHST- 2008/08/21 09:00 [entrez] -AID - jfp_5708k [pii] -PST - ppublish -SO - J Fam Pract. 2008 Aug;57(8 Suppl):S9-16. - -PMID- 18555186 -OWN - NLM -STAT- MEDLINE -DCOM- 20081016 -LR - 20121115 -IS - 1050-1738 (Print) -IS - 1050-1738 (Linking) -VI - 18 -IP - 4 -DP - 2008 May -TI - Fibroblast growth factor 4 gene therapy for chronic ischemic heart disease. -PG - 133-41 -LID - 10.1016/j.tcm.2008.03.002 [doi] -AB - Therapeutic myocardial angiogenesis and arteriogenesis represent a novel - treatment strategy for patients with angina refractory to traditional medical and - surgical therapies. The fibroblast growth factors are a family of proteins that - are known mediators of angio-/arteriogenesis. Based on promising preclinical - animal data, a series of four randomized placebo-controlled clinical trials have - been conducted to determine the safety and efficacy of local delivery of - fibroblast growth factor 4 with the use of adenovirus-vector-mediated gene - transfer to induce myocardial angio-/arteriogenesis in patients with stable - angina. This review describes the scientific rationale underlying these clinical - trials, provides an overview of their results, and discusses the implications for - future studies. -FAU - Kapur, Navin K -AU - Kapur NK -AD - Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD 21287, - USA. -FAU - Rade, Jeffrey J -AU - Rade JJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Trends Cardiovasc Med -JT - Trends in cardiovascular medicine -JID - 9108337 -RN - 0 (Fibroblast Growth Factor 4) -SB - IM -MH - Adenoviridae/genetics -MH - Animals -MH - Chronic Disease -MH - Clinical Trials as Topic -MH - Collateral Circulation -MH - Coronary Circulation -MH - Fibroblast Growth Factor 4/genetics/*metabolism -MH - Gene Transfer Techniques -MH - Genetic Therapy/adverse effects/*methods -MH - Genetic Vectors -MH - Humans -MH - Myocardial Ischemia/genetics/metabolism/physiopathology/*therapy -MH - *Neovascularization, Physiologic -MH - Patient Selection -MH - Time Factors -MH - Treatment Outcome -RF - 38 -EDAT- 2008/06/17 09:00 -MHDA- 2008/10/17 09:00 -CRDT- 2008/06/17 09:00 -PHST- 2008/01/02 00:00 [received] -PHST- 2008/03/17 00:00 [revised] -PHST- 2008/03/20 00:00 [accepted] -PHST- 2008/06/17 09:00 [pubmed] -PHST- 2008/10/17 09:00 [medline] -PHST- 2008/06/17 09:00 [entrez] -AID - S1050-1738(08)00044-3 [pii] -AID - 10.1016/j.tcm.2008.03.002 [doi] -PST - ppublish -SO - Trends Cardiovasc Med. 2008 May;18(4):133-41. doi: 10.1016/j.tcm.2008.03.002. - -PMID- 16521867 -OWN - NLM -STAT- MEDLINE -DCOM- 20060630 -LR - 20190507 -IS - 0256-4947 (Print) -IS - 0975-4466 (Electronic) -IS - 0256-4947 (Linking) -VI - 26 -IP - 1 -DP - 2006 Jan-Feb -TI - Overview of exercise stress testing. -PG - 1-6 -AB - Exercise stress testing is a non-invasive, safe and affordable screening test for - coronary artery disease (CAD), provided there is careful patient selection for - better predictive value. Patients at moderate risk for CAD are best served with - this kind of screening, with the exception of females during their reproductive - period, when a high incidence of false positive results has been reported. - Patients with a high pretest probability for CAD should undergo stress testing - combined with cardiac imaging or cardiac catheterization directly. Data from the - test, other than ECG changes, should be taken into consideration when - interpreting the exercise stress test since it has a strong prognostic value, - i.e. workload, heart rate rise and recovery and blood pressure changes. Only a - low-level exercise stress test can be performed early post myocardial infarction - (first week), and a full exercise test should be delayed 4 to 6 weeks post - uncomplicated myocardial infarction. The ECG interpretation with myocardial - perfusion imaging follows the same criteria, but the sensitivity is much lower - and the specificity is high enough to overrule the imaging part. -FAU - Kharabsheh, Suleiman M -AU - Kharabsheh SM -AD - Department of Cardiovascular Disease, King Faisal Specialist Hospital and - Research Centre, Riyadh, Saudi Arabia. skharabsheh@kfshrc.edu.sa -FAU - Al-Sugair, Abdulaziz -AU - Al-Sugair A -FAU - Al-Buraiki, Jehad -AU - Al-Buraiki J -FAU - Al-Farhan, Juman -AU - Al-Farhan J -LA - eng -PT - Journal Article -PT - Review -PL - Saudi Arabia -TA - Ann Saudi Med -JT - Annals of Saudi medicine -JID - 8507355 -SB - IM -MH - Contraindications -MH - Electrocardiography -MH - *Exercise Test -MH - Female -MH - Humans -MH - Myocardial Infarction -MH - Myocardial Ischemia/diagnosis -MH - Prognosis -MH - Risk Assessment -MH - Sensitivity and Specificity -PMC - PMC6078558 -EDAT- 2006/03/09 09:00 -MHDA- 2006/07/01 09:00 -PMCR- 2006/01/01 -CRDT- 2006/03/09 09:00 -PHST- 2006/03/09 09:00 [pubmed] -PHST- 2006/07/01 09:00 [medline] -PHST- 2006/03/09 09:00 [entrez] -PHST- 2006/01/01 00:00 [pmc-release] -AID - asm-1-1 [pii] -AID - 10.5144/0256-4947.2006.1 [doi] -PST - ppublish -SO - Ann Saudi Med. 2006 Jan-Feb;26(1):1-6. doi: 10.5144/0256-4947.2006.1. - -PMID- 20643208 -OWN - NLM -STAT- MEDLINE -DCOM- 20110314 -LR - 20150831 -IS - 1096-1186 (Electronic) -IS - 1043-6618 (Linking) -VI - 62 -IP - 5 -DP - 2010 Nov -TI - Multifarious molecular signaling cascades of cardiac hypertrophy: can the muddy - waters be cleared? -PG - 365-83 -LID - 10.1016/j.phrs.2010.07.003 [doi] -AB - The mammalian heart during its development and in response to physiological or - pathological stimuli undergoes hypertrophic enlargement, a consequence of an - increase in cardiac myocyte size. Cardiac hypertrophy in response to - biomechanical stress stimuli may be initially a compensatory event, but gradually - becomes a pathological event if the mechanical stress on the myocardium persists. - In fact, studies have shown cardiac hypertrophy as a dominant risk factor for the - development of heart failure and coronary artery disease. A number of complex - signaling cascades were identified that regulate the cardiac hypertrophic - response. Much progress has been made previously in identifying various target - sites and understanding the molecular and cellular processes that are involved in - the development of cardiac hypertrophy and heart failure. This has led drug - discovery research in developing effective therapies to treat various - cardiovascular diseases. However, the available therapeutic agents for the - treatment of heart failure have limited effectiveness in halting the progression - of the disease. Therefore, novel therapeutic strategies are being identified to - inhibit the development of cardiac hypertrophy before heart failure develops. In - this review, we describe multifarious molecular signaling mechanisms involved in - the pathogenesis of cardiac hypertrophy, including tumor necrosis factor-α, - Wnt/Frizzled signals, calcineurin, mitofusin-2, mitogen-activated protein - kinases, Janus kinase, Rho kinase, poly (ADP-ribose) polymerase, transcription - factors, oxidative signals and G-protein-coupled-receptor-associated signaling - system. Elucidation of signaling cascades that initiate cardiac hypertrophy will - open up a new area of research in developing innovative therapeutics for the - treatment of pathological cardiac hypertrophy. -CI - Copyright © 2010 Elsevier Ltd. All rights reserved. -FAU - Balakumar, Pitchai -AU - Balakumar P -AD - Department of Pharmacology, SB College of Pharmacy, Sivakasi 626 130, India. - pbala2006@gmail.com -FAU - Jagadeesh, Gowraganahalli -AU - Jagadeesh G -LA - eng -PT - Journal Article -PT - Review -DEP - 20100717 -PL - Netherlands -TA - Pharmacol Res -JT - Pharmacological research -JID - 8907422 -RN - 0 (Calcineurin Inhibitors) -RN - 0 (Transcription Factors) -RN - 0 (Tumor Necrosis Factor-alpha) -RN - 20762-30-5 (Adenosine Diphosphate Ribose) -RN - EC 2.7.11.24 (Mitogen-Activated Protein Kinases) -RN - EC 3.1.3.16 (Calcineurin) -SB - IM -MH - Adenosine Diphosphate Ribose/metabolism -MH - Animals -MH - Calcineurin/metabolism -MH - Calcineurin Inhibitors -MH - Cardiomegaly/complications/*metabolism/pathology -MH - Female -MH - Heart Failure/etiology/metabolism -MH - Humans -MH - Male -MH - Mitogen-Activated Protein Kinases/metabolism -MH - Myocardium/*metabolism/pathology -MH - Myocytes, Cardiac/metabolism/pathology -MH - *Signal Transduction -MH - Transcription Factors/metabolism -MH - Tumor Necrosis Factor-alpha/metabolism -EDAT- 2010/07/21 06:00 -MHDA- 2011/03/15 06:00 -CRDT- 2010/07/21 06:00 -PHST- 2010/06/05 00:00 [received] -PHST- 2010/07/12 00:00 [revised] -PHST- 2010/07/13 00:00 [accepted] -PHST- 2010/07/21 06:00 [entrez] -PHST- 2010/07/21 06:00 [pubmed] -PHST- 2011/03/15 06:00 [medline] -AID - S1043-6618(10)00143-X [pii] -AID - 10.1016/j.phrs.2010.07.003 [doi] -PST - ppublish -SO - Pharmacol Res. 2010 Nov;62(5):365-83. doi: 10.1016/j.phrs.2010.07.003. Epub 2010 - Jul 17. - -PMID- 23197191 -OWN - NLM -STAT- MEDLINE -DCOM- 20130624 -LR - 20250626 -IS - 2567-689X (Electronic) -IS - 0340-6245 (Linking) -VI - 109 -IP - 1 -DP - 2013 Jan -TI - Impact of clopidogrel and potent P2Y 12 -inhibitors on mortality and stroke in - patients with acute coronary syndrome or undergoing percutaneous coronary - intervention: a systematic review and meta-analysis. -PG - 93-101 -LID - 10.1160/TH12-06-0377 [doi] -AB - Administration of a P2Y 12 -receptor antagonist in addition to aspirin is - mandatory in patients with acute coronary syndromes (ACS) or undergoing - percutaneous coronary intervention (PCI) to reduce the occurrence of thrombotic - events; however, their impact on mortality and stroke is unclear. We aimed to - evaluate the influence of moderate (clopidogrel) or potent (prasugrel/ticagrelor) - P2Y 12 -receptor inhibition on major cardiovascular outcomes among patients with - ACS or undergoing PCI. Systematic literature search was performed to find - randomised, controlled clinical trials comparing the clinical impact of - clopidogrel with placebo or prasugrel/ticagrelor versus clopidogrel. Outcome - measures included cardiovascular death, myocardial infarction (MI), total stroke - and intracranial haemorrhage (ICH). Random-effects model with Mantel-Heanszel - weighting was used to pool outcomes into a meta-analysis. Four studies comparing - clopidogrel with placebo and five trials comparing clopidogrel with new P2Y 12 - -receptor inhibitors were identified including a total of 107,473 patients. - Compared to placebo, clopidogrel reduced the risk of cardiovascular death (odds - ratio [OR]: 0.93; 95% confidence interval [CI]: 0.87-0.99, p=0.02), MI (OR 0.80; - 95%CI 0.74-0.88, p<0.00001) and stroke (OR 0.84; 95%CI 0.72-0.97, p=0.02), - without influencing risk for ICH (OR 0.96; 95%CI 0.69-1.33, p=0.79). Treatment - with prasugrel/ticagrelor provided additional benefit over clopidogrel regarding - cardiovascular mortality (OR 0.86; 95%CI 0.78-0.94, p=0.002) and MI (OR: 0.83; - 95%CI 0.74-0.93, p<0.001), but no advantage in stroke (OR: 1.06; 95%CI 0.88-1.26, - p=0.55) and in ICH (OR: 1.16; 95%CI 0.75-1.81; p=0.49) was observed. Increased - potency of P2Y 12 -receptor inhibition is associated with decreased risk in - cardiovascular death and MI; however, this association is not true in case of - stroke, where potent P2Y 12 -receptor antagonists have no incremental benefit - over clopidogrel. -FAU - Aradi, Dániel -AU - Aradi D -AD - University of Pécs, Heart Institute, Division of Interventional Cardiology, - Hungary. daniel_aradi@yahoo.com -FAU - Komócsi, András -AU - Komócsi A -FAU - Vorobcsuk, András -AU - Vorobcsuk A -FAU - Serebruany, Victor L -AU - Serebruany VL -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20121129 -PL - Germany -TA - Thromb Haemost -JT - Thrombosis and haemostasis -JID - 7608063 -RN - 0 (P2RY12 protein, human) -RN - 0 (Piperazines) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Purinergic P2Y Receptor Antagonists) -RN - 0 (Receptors, Purinergic P2Y12) -RN - 0 (Thiophenes) -RN - A74586SNO7 (Clopidogrel) -RN - G89JQ59I13 (Prasugrel Hydrochloride) -RN - GLH0314RVC (Ticagrelor) -RN - K72T3FS567 (Adenosine) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Acute Coronary Syndrome/blood/complications/*drug therapy/mortality -MH - Adenosine/analogs & derivatives/therapeutic use -MH - Aged -MH - Clopidogrel -MH - Coronary Thrombosis/blood/etiology/mortality/*prevention & control -MH - Female -MH - Humans -MH - Intracranial Hemorrhages/chemically induced -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/etiology/mortality/prevention & control -MH - Odds Ratio -MH - Percutaneous Coronary Intervention/*adverse effects/mortality -MH - Piperazines/therapeutic use -MH - Platelet Aggregation Inhibitors/adverse effects/*therapeutic use -MH - Prasugrel Hydrochloride -MH - Purinergic P2Y Receptor Antagonists/adverse effects/*therapeutic use -MH - Receptors, Purinergic P2Y12/blood/*drug effects -MH - Risk Assessment -MH - Risk Factors -MH - Stroke/blood/etiology/mortality/*prevention & control -MH - Thiophenes/therapeutic use -MH - Ticagrelor -MH - Ticlopidine/adverse effects/*analogs & derivatives/therapeutic use -MH - Treatment Outcome -EDAT- 2012/12/01 06:00 -MHDA- 2013/06/26 06:00 -CRDT- 2012/12/01 06:00 -PHST- 2012/06/06 00:00 [received] -PHST- 2012/09/28 00:00 [accepted] -PHST- 2012/12/01 06:00 [entrez] -PHST- 2012/12/01 06:00 [pubmed] -PHST- 2013/06/26 06:00 [medline] -AID - 12-06-0377 [pii] -AID - 10.1160/TH12-06-0377 [doi] -PST - ppublish -SO - Thromb Haemost. 2013 Jan;109(1):93-101. doi: 10.1160/TH12-06-0377. Epub 2012 Nov - 29. - -PMID- 23439018 -OWN - NLM -STAT- MEDLINE -DCOM- 20130502 -LR - 20161125 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 29 -IP - 3 -DP - 2013 Mar -TI - Imaging heart failure: current and future applications. -PG - 317-28 -LID - S0828-282X(13)00027-5 [pii] -LID - 10.1016/j.cjca.2013.01.006 [doi] -AB - A variety of cardiac imaging tests are used to help manage patients with heart - failure (HF). This article reviews current and future HF applications for the - major noninvasive imaging modalities: transthoracic echocardiography (TTE), - single-photon emission computed tomography (SPECT), positron emission tomography - (PET), cardiovascular magnetic resonance (CMR), and computed tomography (CT). TTE - is the primary imaging test used in the evaluation of patients with HF, given its - widespread availability and reliability in assessing cardiac structure and - function. Recent developments in myocardial strain, 3-dimensional TTE, and echo - contrast appear to offer superior diagnostic and prognostic information. SPECT - imaging is a common method employed to detect ischemia and viability in patients - with HF; however, PET offers higher diagnostic accuracy for both. Ongoing study - of sympathetic and molecular imaging techniques may enable early disease - detection, better risk stratification, and ultimately targeted treatment - interventions. CMR provides high-quality information on cardiac structure and - function and allows the characterization of myocardial tissue. Myocardial late - gadolinium enhancement allows the determination of HF etiology and may predict - patient outcomes and treatment response. Cardiac CT has become a reliable means - for detecting coronary artery disease, and recent advances have enabled - concurrent myocardial function, perfusion, and scar analyses. Overall, available - imaging methods provide reliable measures of cardiac performance in HF, and - recent advances will allow detection of subclinical disease. More data are needed - demonstrating the specific clinical value of imaging methods and particularly - subclinical disease detection in large-scale, clinical settings. -CI - Copyright © 2013 Canadian Cardiovascular Society. Published by Elsevier Inc. All - rights reserved. -FAU - Paterson, Ian -AU - Paterson I -AD - Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, - Canada. ip3@ualberta.ca -FAU - Mielniczuk, Lisa M -AU - Mielniczuk LM -FAU - O'Meara, Eileen -AU - O'Meara E -FAU - So, Aaron -AU - So A -FAU - White, James A -AU - White JA -LA - eng -GR - Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Cardiac Imaging Techniques/methods/trends -MH - Diagnostic Imaging/*methods/*trends -MH - Early Diagnosis -MH - Echocardiography/trends -MH - Heart Failure/*diagnosis/diagnostic imaging/therapy -MH - Humans -MH - Magnetic Resonance Imaging/trends -MH - Positron-Emission Tomography/trends -MH - Predictive Value of Tests -MH - Prognosis -MH - Reproducibility of Results -MH - Risk Assessment -MH - Sensitivity and Specificity -MH - Tomography, Emission-Computed, Single-Photon/trends -MH - Tomography, X-Ray Computed/trends -EDAT- 2013/02/27 06:00 -MHDA- 2013/05/03 06:00 -CRDT- 2013/02/27 06:00 -PHST- 2012/08/16 00:00 [received] -PHST- 2013/01/16 00:00 [revised] -PHST- 2013/01/16 00:00 [accepted] -PHST- 2013/02/27 06:00 [entrez] -PHST- 2013/02/27 06:00 [pubmed] -PHST- 2013/05/03 06:00 [medline] -AID - S0828-282X(13)00027-5 [pii] -AID - 10.1016/j.cjca.2013.01.006 [doi] -PST - ppublish -SO - Can J Cardiol. 2013 Mar;29(3):317-28. doi: 10.1016/j.cjca.2013.01.006. - -PMID- 17568279 -OWN - NLM -STAT- MEDLINE -DCOM- 20070815 -LR - 20220412 -IS - 1558-2027 (Print) -IS - 1558-2027 (Linking) -VI - 8 -IP - 7 -DP - 2007 Jul -TI - Congenitally persistent left superior vena cava: a possible unpleasant problem - during invasive procedures. -PG - 483-7 -AB - The persistence of the left superior vena cava is the most common thoracic vein - anomaly, but, nevertheless, it continues to be an unpleasant finding during - invasive diagnostic cardiovascular procedures and is sometimes a challenge during - invasive therapeutic interventions. Persistent left superior vena cava usually - occurs in 0.5% of the normal population and 0.47% of patients undergoing - pacemaker or implantable cardioverter defibrillator implantation. The incidence - in congenital heart disease varies (2-5%), and it is more frequent in stenosis or - pulmonary atresia, D-transposition, complete atrioventricular septal defects, and - anomalous pulmonary vein drainage. The diagnosis is almost always incidental, - during anaesthesiological procedures such as central vein placement, or - diagnostic cardiovascular procedures, such as right heart catheterization, but it - may sometimes be discovered during therapeutic paediatric cardiac - catheterization, such as during patent foramen ovale or atrial septal defect - transcatheter closure. Echocardiography is useful to identify patients in whom - computed tomography and especially magnetic resonance imaging may pose a - definitive diagnosis. In indicated cases, when cyanosis is present and the - anomaly is isolated, treatment options include surgical ligation and - transcatheter closure using large occluder devices, whereas more challenging - surgical repairs are needed when the anomaly is associated with other complex - congenital heart diseases. Different specialists at different levels such as - anaesthesiologists, invasive cardiologists, electrophysiologists and cardiac - surgeons should be aware of the variety of technical problems that may be caused - by a persistent LSVC. -FAU - Rigatelli, Gianluca -AU - Rigatelli G -AD - Interventional Cardiology Unit, Division of Cardiology, Rovigo General Hospital, - Rovigo, Italy. jackyheart@hotmail.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Cardiovasc Med (Hagerstown) -JT - Journal of cardiovascular medicine (Hagerstown, Md.) -JID - 101259752 -SB - IM -MH - Cardiovascular Surgical Procedures -MH - Coronary Circulation -MH - Diagnostic Imaging -MH - Diagnostic Techniques, Cardiovascular -MH - Heart Defects, Congenital/diagnosis/therapy -MH - Humans -MH - Vena Cava, Superior/*abnormalities/embryology -RF - 35 -EDAT- 2007/06/15 09:00 -MHDA- 2007/08/19 09:00 -CRDT- 2007/06/15 09:00 -PHST- 2007/06/15 09:00 [pubmed] -PHST- 2007/08/19 09:00 [medline] -PHST- 2007/06/15 09:00 [entrez] -AID - 01244665-200707000-00002 [pii] -AID - 10.2459/01.JCM.0000278448.89365.55 [doi] -PST - ppublish -SO - J Cardiovasc Med (Hagerstown). 2007 Jul;8(7):483-7. doi: - 10.2459/01.JCM.0000278448.89365.55. - -PMID- 21717473 -OWN - NLM -STAT- MEDLINE -DCOM- 20111201 -LR - 20240718 -IS - 1932-8737 (Electronic) -IS - 0160-9289 (Print) -IS - 0160-9289 (Linking) -VI - 34 -IP - 8 -DP - 2011 Aug -TI - Peripheral arterial disease--what do we need to know? -PG - 478-82 -LID - 10.1002/clc.20925 [doi] -AB - Peripheral artery disease (PAD) results from progressive narrowing of arteries - secondary to atherosclerosis and is defined as an Ankle Brachial Index of <0.9. - PAD is highly prevalent and is an increasing burden on both the economy and the - patient, especially given the rapid shift in demographics in the United States. - Despite its prevalence and association with cardiovascular disease, PAD is still - underdiagnosed and undertreated. This may, in part, be related to lack of - recognition from the physician's side or paucity of evidence from clinical - trials. It has been shown that medical therapy approved for cardiovascular - disease is effective in the treatment of PAD and decreases cardiovascular events. - Various revascularization strategies are also available for improving symptoms - and quality of life in these patients, yet they are underutilized. In an attempt - to increase its recognition, PAD has been considered a coronary artery disease - equivalent. This article reviews the diagnosis and management of PAD. © 2011 - Wiley Periodicals, Inc. The authors have no funding, financial relationships, or - conflicts of interest to disclose. -CI - © 2011 Wiley Periodicals, Inc. -FAU - Shanmugasundaram, Madhan -AU - Shanmugasundaram M -AD - Sarver Heart Center, Section of Cardiology, University of Arizona College of - Medicine, Tucson, Arizona 85724, USA. smadhan13@gmail.com -FAU - Ram, Vinny K -AU - Ram VK -FAU - Luft, Ulrich C -AU - Luft UC -FAU - Szerlip, Molly -AU - Szerlip M -FAU - Alpert, Joseph S -AU - Alpert JS -LA - eng -PT - Journal Article -PT - Review -DEP - 20110629 -PL - United States -TA - Clin Cardiol -JT - Clinical cardiology -JID - 7903272 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Cardiovascular Agents/therapeutic use -MH - Diagnostic Techniques, Cardiovascular -MH - Endovascular Procedures -MH - Humans -MH - *Peripheral Arterial Disease/diagnosis/epidemiology/physiopathology/therapy -MH - Predictive Value of Tests -MH - Risk Assessment -MH - Risk Factors -MH - Risk Reduction Behavior -MH - Treatment Outcome -MH - Vascular Surgical Procedures -PMC - PMC6652699 -EDAT- 2011/07/01 06:00 -MHDA- 2011/12/13 00:00 -PMCR- 2011/06/29 -CRDT- 2011/07/01 06:00 -PHST- 2011/04/28 00:00 [received] -PHST- 2011/05/11 00:00 [accepted] -PHST- 2011/07/01 06:00 [entrez] -PHST- 2011/07/01 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -PHST- 2011/06/29 00:00 [pmc-release] -AID - CLC20925 [pii] -AID - 10.1002/clc.20925 [doi] -PST - ppublish -SO - Clin Cardiol. 2011 Aug;34(8):478-82. doi: 10.1002/clc.20925. Epub 2011 Jun 29. - -PMID- 24383380 -OWN - NLM -STAT- MEDLINE -DCOM- 20140123 -LR - 20141120 -IS - 0966-8519 (Print) -IS - 0966-8519 (Linking) -VI - 22 -IP - 5 -DP - 2013 Sep -TI - Takotsubo cardiomyopathy after minimally invasive mitral valve surgery: clinical - case and review. -PG - 675-81 -AB - A sudden, unexpected, reversible, severe left ventricular dysfunction, mimicking - an acute myocardial infarction without demonstrable obstructive coronary artery - stenosis, was first recognized in Japan in 1990 and originally termed takotsubo - cardiomyopathy. In 2006, the American Heart Association included takotsubo - cardiomyopathy into its classification of primary acquired cardiomyopathy. The - true incidence of takotsubo cardiomyopathy in the community is difficult to - estimate. In fact, despite an increasing awareness, this syndrome has to date - been under-recognized and misdiagnosed, mainly because of the transitory natures - of its clinical and instrumental features. The study aim was to investigate the - association between the occurrence of takotsubo cardiomyopathy and emotional or - physical stressors, as described also in the setting of various surgical - procedures. The case is also described of a 77-year-old woman who suffered a - transient left ventricular dysfunction soon after cardiac surgery for valvular - disease and epicardial cryoablation of atrial fibrillation. -FAU - Attisani, Matteo -AU - Attisani M -AD - Department of Thoracic and Cardiovascular Surgery, Division of Cardiac Surgery, - University of Turin, San Giovanni Battista Hospital, Turin, Italy. - matteoatti@libero.it -FAU - Campanella, Antonio -AU - Campanella A -AD - Department of Thoracic and Cardiovascular Surgery, Division of Cardiac Surgery, - University of Turin, San Giovanni Battista Hospital, Turin, Italy. -FAU - Boffini, Massimo -AU - Boffini M -AD - Department of Thoracic and Cardiovascular Surgery, Division of Cardiac Surgery, - University of Turin, San Giovanni Battista Hospital, Turin, Italy. -FAU - Rinaldi, Mauro -AU - Rinaldi M -AD - Department of Thoracic and Cardiovascular Surgery, Division of Cardiac Surgery, - University of Turin, San Giovanni Battista Hospital, Turin, Italy. -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - England -TA - J Heart Valve Dis -JT - The Journal of heart valve disease -JID - 9312096 -SB - IM -MH - Aged -MH - Female -MH - Heart Valve Prosthesis Implantation/*adverse effects/methods -MH - Humans -MH - Minimally Invasive Surgical Procedures/*adverse effects -MH - Mitral Valve/*surgery -MH - Mitral Valve Insufficiency/*surgery -MH - *Postoperative Complications -MH - Takotsubo Cardiomyopathy/diagnosis/*etiology -EDAT- 2014/01/05 06:00 -MHDA- 2014/01/24 06:00 -CRDT- 2014/01/04 06:00 -PHST- 2014/01/04 06:00 [entrez] -PHST- 2014/01/05 06:00 [pubmed] -PHST- 2014/01/24 06:00 [medline] -PST - ppublish -SO - J Heart Valve Dis. 2013 Sep;22(5):675-81. - -PMID- 21547469 -OWN - NLM -STAT- MEDLINE -DCOM- 20110923 -LR - 20220311 -IS - 1573-2584 (Electronic) -IS - 0301-1623 (Linking) -VI - 43 -IP - 2 -DP - 2011 Jun -TI - Allopurinol, uric acid, and oxidative stress in cardiorenal disease. -PG - 441-9 -LID - 10.1007/s11255-011-9929-6 [doi] -AB - In humans, the hepatic end product of purine metabolism is uric acid. Serum uric - acid levels physiologically and gradually rise during human lifetime. - Hyperuricemia also arises from excess dietary purine or ethanol intake, decreased - renal excretion of uric acid, tumor lysis in lymphoma, leukemia or solid tumors, - and sometimes pharmacotherapy. The definition of hyperuricemia is currently - arbitrary. Hyperuricemia is associated with chronic kidney disease, arterial - hypertension, coronary artery and heart disease, cerebrovascular disease and - diabetes mellitus. Xanthine oxidase, a hepatic enzyme, catalyzes the production - of uric acid, nitric oxide, and reactive oxygen species, which potentially damage - deoxyribonucleic acid, ribonucleic acid and proteins, inactivate enzymes, oxidize - amino acids and convert poly-unsaturated fatty acids to lipids. This is believed - to contribute to atherosclerosis, endothelial dysfunction, renovascular - hypertension, and cardiovascular disease. Xanthine oxidase inhibition efficiently - blocks uric acid generation, and this improves glomerular filtration rates, - systemic blood pressure, and cerebro-cardiovascular outcomes. Here, data from - animal, in vivo, retro- and prospective, and interventional studies are reported. -FAU - Riegersperger, Markus -AU - Riegersperger M -AD - Division of Nephrology and Dialysis, Department of Medicine III, Medical - University Vienna, Währinger Gürtel 18-20, A 1090 Vienna, Austria. - markus.riegersperger@meduniwien.ac.at -FAU - Covic, Adrian -AU - Covic A -FAU - Goldsmith, David -AU - Goldsmith D -LA - eng -PT - Journal Article -PT - Review -DEP - 20110310 -PL - Netherlands -TA - Int Urol Nephrol -JT - International urology and nephrology -JID - 0262521 -RN - 0 (Enzyme Inhibitors) -RN - 268B43MJ25 (Uric Acid) -RN - 63CZ7GJN5I (Allopurinol) -SB - IM -MH - Allopurinol/*therapeutic use -MH - Animals -MH - Cardiovascular Diseases/etiology/metabolism/prevention & control -MH - Enzyme Inhibitors/*therapeutic use -MH - Humans -MH - Hyperuricemia/complications/*drug therapy/*metabolism -MH - *Oxidative Stress -MH - Renal Insufficiency, Chronic/etiology/metabolism/prevention & control -MH - Uric Acid/*metabolism -EDAT- 2011/05/07 06:00 -MHDA- 2011/09/29 06:00 -CRDT- 2011/05/07 06:00 -PHST- 2010/12/06 00:00 [received] -PHST- 2011/02/16 00:00 [accepted] -PHST- 2011/05/07 06:00 [entrez] -PHST- 2011/05/07 06:00 [pubmed] -PHST- 2011/09/29 06:00 [medline] -AID - 10.1007/s11255-011-9929-6 [doi] -PST - ppublish -SO - Int Urol Nephrol. 2011 Jun;43(2):441-9. doi: 10.1007/s11255-011-9929-6. Epub 2011 - Mar 10. - -PMID- 20807188 -OWN - NLM -STAT- MEDLINE -DCOM- 20110729 -LR - 20191027 -IS - 1875-6212 (Electronic) -IS - 1570-1611 (Linking) -VI - 9 -IP - 3 -DP - 2011 May -TI - Hypoxia-inducible factor-1 in arterial disease: a putative therapeutic target. -PG - 333-49 -AB - Hypoxia-inducible factor-1 (HIF-1) is a nuclear transcription factor that is - upregulated in hypoxia and co-ordinates the adaptive response to hypoxia by - driving the expression of over 100 genes. In facilitating tissues to adapt to - hypoxia, HIF-1 may have a role in reducing the cellular damage induced by - ischaemia, such as that seen in peripheral arterial disease (PAD), or following - acute ischaemic insults such as stroke and myocardial infarction. This therefore - raises the possibility of HIF-1 modulation in such contexts to reduce the - consequences of ischaemic injury. HIF1 has further been implicated in the - pathogenesis of atherosclerosis, abdominal aortic aneurysm (AAA) formation, - pulmonary hypertension and systemic hypertension associated with obstructive - sleep apnoea. Through a better understanding of the role of HIF-1 in these - disease processes, novel treatments which target HIF-1 pathway may be considered. - This review summarises the role of HIF-1 in arterial disease, specifically its - role in atherosclerosis, ischaemic heart disease, in-stent restenosis following - coronary revascularisation, stroke, PAD, AAA formation, pulmonary artery - hypertension and systemic hypertension. The potential for exploiting the HIF-1 - signalling pathway in developing therapeutics for these conditions is discussed, - including progress made so far, with attention given to studies looking into the - use of prolyl-hydroxylase inhibitors. -FAU - Kasivisvanathan, Veeru -AU - Kasivisvanathan V -AD - Imperial Vascular Unit, Imperial College London, Charing Cross Hospital, London, - UK. -FAU - Shalhoub, Joseph -AU - Shalhoub J -FAU - Lim, Chung S -AU - Lim CS -FAU - Shepherd, Amanda C -AU - Shepherd AC -FAU - Thapar, Ankur -AU - Thapar A -FAU - Davies, Alun H -AU - Davies AH -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Vasc Pharmacol -JT - Current vascular pharmacology -JID - 101157208 -RN - 0 (Enzyme Inhibitors) -RN - 0 (Hypoxia-Inducible Factor 1) -RN - EC 1.14.11.2 (Procollagen-Proline Dioxygenase) -SB - IM -MH - Animals -MH - *Drug Delivery Systems -MH - Enzyme Inhibitors/pharmacology -MH - Humans -MH - Hypoxia-Inducible Factor 1/*metabolism -MH - Ischemia/physiopathology -MH - Procollagen-Proline Dioxygenase/antagonists & inhibitors -MH - Signal Transduction -MH - Vascular Diseases/drug therapy/*physiopathology -EDAT- 2010/09/03 06:00 -MHDA- 2011/07/30 06:00 -CRDT- 2010/09/03 06:00 -PHST- 2010/06/17 00:00 [received] -PHST- 2010/08/31 00:00 [accepted] -PHST- 2010/09/03 06:00 [entrez] -PHST- 2010/09/03 06:00 [pubmed] -PHST- 2011/07/30 06:00 [medline] -AID - BSP/CVP/E-Pub/0000104 [pii] -AID - 10.2174/157016111795495602 [doi] -PST - ppublish -SO - Curr Vasc Pharmacol. 2011 May;9(3):333-49. doi: 10.2174/157016111795495602. - -PMID- 18718974 -OWN - NLM -STAT- MEDLINE -DCOM- 20100618 -LR - 20090519 -IS - 1473-0480 (Electronic) -IS - 0306-3674 (Linking) -VI - 43 -IP - 5 -DP - 2009 May -TI - Sudden cardiac arrest in children and young athletes: the importance of a - detailed personal and family history in the pre-participation evaluation. -PG - 336-41 -LID - 10.1136/bjsm.2008.050534 [doi] -AB - Healthcare providers have become more aware of and concerned about paediatric - sudden cardiac arrest. The diseases predisposing a patient to sudden cardiac - arrest are all infrequently encountered. However, a detailed and comprehensive - patient and family history may reveal warning signs and symptoms that identify a - patient at higher risk for sudden cardiac arrest. Since many of these diseases - are genetic, extensive family evaluation may uncover a previously undetected - cardiac disease process and as well direct the development of a complete family - evaluation and treatment plan. Published data document that in many cases - preceding warning symptoms and signs are present, but may be misinterpreted or - disregarded by medical staff. Attention to the details of patient history, family - history and physical exam is critical to the success of any detection strategy, - which can and should be widely applied. -FAU - Campbell, R M -AU - Campbell RM -AD - Children's Healthcare of Atlanta Sibley Heart Center, 2835 Brandywine Road, Suite - 300, Atlanta 30341, USA. campbellr@kidsheart.com -FAU - Berger, S -AU - Berger S -FAU - Drezner, J -AU - Drezner J -LA - eng -PT - Journal Article -PT - Review -DEP - 20080821 -PL - England -TA - Br J Sports Med -JT - British journal of sports medicine -JID - 0432520 -SB - IM -MH - Adolescent -MH - Arrhythmias, Cardiac/complications -MH - *Athletes -MH - Cardiomyopathies/genetics -MH - Child -MH - Coronary Vessel Anomalies/genetics -MH - Death, Sudden, Cardiac/epidemiology/*etiology/prevention & control -MH - Diagnosis, Differential -MH - Humans -MH - Incidence -MH - Marfan Syndrome/complications -MH - Risk Assessment -MH - Risk Factors -MH - Young Adult -RF - 47 -EDAT- 2008/08/23 09:00 -MHDA- 2010/06/19 06:00 -CRDT- 2008/08/23 09:00 -PHST- 2008/08/23 09:00 [pubmed] -PHST- 2010/06/19 06:00 [medline] -PHST- 2008/08/23 09:00 [entrez] -AID - bjsm.2008.050534 [pii] -AID - 10.1136/bjsm.2008.050534 [doi] -PST - ppublish -SO - Br J Sports Med. 2009 May;43(5):336-41. doi: 10.1136/bjsm.2008.050534. Epub 2008 - Aug 21. - -PMID- 22724418 -OWN - NLM -STAT- MEDLINE -DCOM- 20130425 -LR - 20220410 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 18 -IP - 33 -DP - 2012 -TI - Platelet turnover in atherothrombotic disease. -PG - 5328-43 -AB - Platelets play a pivotal role in primary hemostasis where their rapid response to - vascular injury prevents excessive bleeding. To accomplish this, platelets are - enriched in membrane receptors and cytoplasmic enzymes with often redundant and - self-amplifying functions leading to platelet activation, release into the - bloodstream of hemostatically active compounds and culminating with thrombus - formation. However, the same process in the pathological state of atherosclerosis - can lead to thrombotic complications such as an acute coronary syndrome or - stroke. The role of platelets in this process is more extensive than previously - believed. Several lines of evidence suggest that platelets contribute not only to - the acute thrombotic events in atherosclerosis, but also to disease initiation - and progression. This review focuses on the role of platelet heterogeneity and - turnover in atherothrombotic disease. Specifically, this article covers (a) the - regulation of platelet formation; (b) the role of the heterogeneity of platelets - in atherothrombotic diseases; (c) the disease-modifying effect of platelets on - the development of atherosclerosis; and (d) the modifying effect of - atherosclerotic disease on platelet production and function; (e) the platelet - indices influencing platelet responsiveness to antiplatelet therapies; and - finally (f) the potential novel therapeutic modalities that could be applied in - atherothrombosis. -FAU - Lordkipanidzé, Marie -AU - Lordkipanidzé M -AD - Centre for Cardiovascular Sciences, Institute of Biomedical Research, College of - Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 - 2TT, United Kingdom. m.lordkipanidze@bham.ac.uk -LA - eng -GR - British Heart Foundation/United Kingdom -GR - Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Animals -MH - Atherosclerosis/*blood/drug therapy/pathology -MH - Blood Platelets/drug effects/*metabolism/pathology -MH - Cell Death -MH - Cellular Senescence -MH - Humans -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Platelet Function Tests -MH - Thrombopoiesis -MH - Thrombosis/*blood/drug therapy/pathology -EDAT- 2012/06/26 06:00 -MHDA- 2013/04/26 06:00 -CRDT- 2012/06/26 06:00 -PHST- 2012/04/16 00:00 [received] -PHST- 2012/05/01 00:00 [accepted] -PHST- 2012/06/26 06:00 [entrez] -PHST- 2012/06/26 06:00 [pubmed] -PHST- 2013/04/26 06:00 [medline] -AID - CPD-EPUB-20120619-11 [pii] -AID - 10.2174/138161212803251952 [doi] -PST - ppublish -SO - Curr Pharm Des. 2012;18(33):5328-43. doi: 10.2174/138161212803251952. - -PMID- 24155531 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20240518 -IS - 0898-5901 (Print) -IS - 1884-7269 (Electronic) -IS - 0898-5901 (Linking) -VI - 20 -IP - 3 -DP - 2011 -TI - Clinical application of laser treatment for cardiovascular surgery. -PG - 217-32 -AB - BACKGROUND: Recently, several kinds of lasers have been widely employed in the - field of medicine and surgery. However, laser applications are very rare in the - field of cardiovascular surgery throughout the world. So, we have experimentally - tried to use lasers in the field of cardiovascular surgery. There were three - categories: 1) Transmyocardial laser revascularization (TMLR), 2) Laser vascular - anastomosis, and 3) Laser angioplasty in the peripheral arterial diseases. By the - way, surgery for ischemic heart disease has been widely performed in Japan. - Especially coronary artery bypass grafting (CABG) for these patients has been - done as a popular surgical method. Among these patients there are a few cases for - whom CABG and percutaneous coronary intervention (PCI) could not be carried out, - because of diffuse stenosis and small caliber of coronary arteries. Materials and - methods of TMLR: A new method of tranasmyocardial revascularization by CO2 laser - (output 100 W, irradiation time 0.2 sec) was experimentally performed to save - severely ill patients. In this study, a feasibility of transmyocardial laser - revascularization from left ventricular cavity through artificially created - channels by laser was precisely evaluated. RESULTS: In trials on dogs laser holes - 0.2mm in diameter have been shown microscopically to be patent even 3 years after - their creation, thus this procedure could be used as a new method of - transmyocardial laser revascularization. Clinical application of TMLR: - Subsequently, transmyocardial laser revascularization was employed in a - 55-year-old male patient with severe angina pectoris who had undergone - pericardiectomy 7 years before. He was completely recovered from severe chest - pain. Conclusions of TMLR: This patient was the first successful case in the - world with TMLR alone. This method might be done for the patients who - percutaneous coronary intervention and coronary artery bypass grafting could be - carried out. Laser vascular anastomosis: At present time, in vascular surgery - there are some problems to keep long-term patency after anastomosis of the - conventional suture method, especially for small-caliber vessels. Materials and - methods of Laser vascular anastomosis: From these standpoints, a low energy CO2 - laser was employed experimentally in vascular anastomosis for small-caliber - vessels. Resullts of Laser vascular anastomosis: From preliminary experiments it - could be concluded that the optimal laser output was 20-40 mW and irradiation - time was 6-12 sec/mm for vascular anastomosis of small-caliber vessels in the - extremities. And then, histologic findings and intensity of the laser anastomotic - sites were investigated thereafter. Subseqently, good enough intensity and good - healing of laser anastomotic sites as well as the conventional suture method - could be observed. There were no statistic differences between laser and suture - methods. A feasibility of laser anastomosis could be considered and clinical - application could be recognized. Clinical applications of Laser vascular - anastomosis: On February 21, 1985, arterio-venous laser anastomosis for the - patient with renal failure was smoothly done and she could accept hemodialysis. - Conclusions of Laser vascular anastomosis: This patient was the first clinical - successful case in the world. Thereafter, Laser vascular anastomosis were in 111 - patients with intermittent claudication, refractory crural ulcer, and coronary - disorders. Thereafter, they are going well. Laser angioplasty: Laser angioplasty - for peripheral arterial diseases. There are many methods to treat peripheral - arterial diseases such as balloon method, atherectomy, laser technique and - stenting graft in the field of endovascular treatment. Recent years, minimal - invasive treatment should be employed even in the surgical treatment. However, - there are different images between these methods. Materials and methods of Laser - angioplasty: We have chosen to use laser for endovascular treatment for - peripheral arterial diseases. We have tried to check between laser energy and - vessel wall. Results of Laser angioplasty: Subsequently, it could be concluded - that optimal conditions for laser angioplasty were 6 W in output and irradiation - time was 5 sec. And with another method of feedback control system, temperature - of metal tip probe was 200°C and irradiation time was 5 sec for each shot. And - histological study and feasibility of angioscopic guidance could be done and - clinical application was started. Until now, 115 patients were successfully - treated with their life longevity. Conclusions of Laser angioplasty: Thus, laser - applications were useful methods to treat a lot of patients with some ischemic - problems. -FAU - Okada, Masayoshi -AU - Okada M -AD - International Institute for Advanced General Medicine. -FAU - Yoshida, Masato -AU - Yoshida M -FAU - Tsuji, Yoshihiko -AU - Tsuji Y -FAU - Horii, Hiroyuki -AU - Horii H -LA - eng -PT - Journal Article -PT - Review -PL - Japan -TA - Laser Ther -JT - Laser therapy -JID - 8914401 -PMC - PMC3799031 -EDAT- 2011/01/01 00:00 -MHDA- 2011/01/01 00:01 -PMCR- 2011/07/01 -CRDT- 2013/10/25 06:00 -PHST- 2011/05/03 00:00 [received] -PHST- 2011/07/29 00:00 [accepted] -PHST- 2013/10/25 06:00 [entrez] -PHST- 2011/01/01 00:00 [pubmed] -PHST- 2011/01/01 00:01 [medline] -PHST- 2011/07/01 00:00 [pmc-release] -AID - 10.5978/islsm.20.217 [doi] -PST - ppublish -SO - Laser Ther. 2011;20(3):217-32. doi: 10.5978/islsm.20.217. - -PMID- 24041566 -OWN - NLM -STAT- MEDLINE -DCOM- 20140424 -LR - 20220317 -IS - 1527-3288 (Electronic) -IS - 0147-9563 (Linking) -VI - 43 -IP - 2 -DP - 2014 Mar-Apr -TI - Large embolus in transit - an unresolved therapeutic dilemma (case report and - review of literature). -PG - 152-4 -LID - S0147-9563(13)00288-4 [pii] -LID - 10.1016/j.hrtlng.2013.08.005 [doi] -AB - Floating right heart thrombus, also known as "emboli in transit" is a potentially - fatal condition, of varying etiology and usually coexisting with massive - pulmonary embolism. Although the mortality rate is as high as 40%, there are no - established therapeutic guidelines. A case is presented of an 84 year old female - with a history of colon cancer and coronary artery disease who presented with - sudden onset unresponsiveness. She was intubated in the ED and started on - intravenous pressor support. A free floating large right ventricular thrombus and - dilated right ventricle were noted on transthoracic echocardiogram (TTE). She was - managed medically with good short term outcome. Floating right heart thrombus is - a rare occurrence. Recognition of signs and symptoms along with early TTE is - critical for diagnosis and consideration of treatment modality. The existing - literature does not offer a clear consensus for management of pulmonary embolism - with co-existing mobile intra-cardiac thrombus. Choice of treatment is crucial - and should be considered on a case-by-case basis after careful assessment of - indications, contraindications, risks and benefits. -CI - Copyright © 2014 Elsevier Inc. All rights reserved. -FAU - Agarwal, Vratika -AU - Agarwal V -AD - Department of Medicine, Staten Island University Hospital, 475 Seaview Ave., - Staten Island, NY 10305, USA. Electronic address: vratika.agarwal@gmail.com. -FAU - Nalluri, Nikhil -AU - Nalluri N -AD - Department of Medicine, Staten Island University Hospital, 475 Seaview Ave., - Staten Island, NY 10305, USA. -FAU - Shariff, Masood A -AU - Shariff MA -AD - Department of Cardiothoracic Research, Staten Island University Hospital, Staten - Island, NY, USA. -FAU - Akhtar, Muhammad S -AU - Akhtar MS -AD - Department of Cardiology, Staten Island University Hospital, Staten Island, NY, - USA. -FAU - Olkovsky, Yefim -AU - Olkovsky Y -AD - Department of Cardiology, Staten Island University Hospital, Staten Island, NY, - USA. -FAU - Kitsis, Paul E -AU - Kitsis PE -AD - Department of Critical Care Medicine, Staten Island University Hospital, Staten - Island, NY, USA. -FAU - Nabagiez, John P -AU - Nabagiez JP -AD - Department of Cardiothoracic Surgery, Staten Island University Hospital, Staten - Island, NY, USA. -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20130914 -PL - United States -TA - Heart Lung -JT - Heart & lung : the journal of critical care -JID - 0330057 -SB - IM -MH - Aged, 80 and over -MH - Echocardiography -MH - Female -MH - Heart Diseases/diagnostic imaging/*drug therapy/surgery -MH - Humans -MH - *Thrombolytic Therapy -MH - Thrombosis/diagnostic imaging/*drug therapy/surgery -OTO - NOTNLM -OT - Critical care -OT - Right heart thrombus -OT - Thrombolytic therapy -OT - Transthoracic echocardiography -EDAT- 2013/09/18 06:00 -MHDA- 2014/04/25 06:00 -CRDT- 2013/09/18 06:00 -PHST- 2013/06/17 00:00 [received] -PHST- 2013/08/02 00:00 [revised] -PHST- 2013/08/05 00:00 [accepted] -PHST- 2013/09/18 06:00 [entrez] -PHST- 2013/09/18 06:00 [pubmed] -PHST- 2014/04/25 06:00 [medline] -AID - S0147-9563(13)00288-4 [pii] -AID - 10.1016/j.hrtlng.2013.08.005 [doi] -PST - ppublish -SO - Heart Lung. 2014 Mar-Apr;43(2):152-4. doi: 10.1016/j.hrtlng.2013.08.005. Epub - 2013 Sep 14. - -PMID- 20934551 -OWN - NLM -STAT- MEDLINE -DCOM- 20101028 -LR - 20151119 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 160 -IP - 4 -DP - 2010 Oct -TI - Novel biomarkers in cardiovascular disease: update 2010. -PG - 583-94 -LID - 10.1016/j.ahj.2010.06.010 [doi] -AB - The rapid evaluation of patients presenting with symptoms suggestive of an acute - coronary syndrome is of great clinical relevance. Biomarkers have become - increasingly important in this setting to supplement electrocardiographic - findings and patient history because one or both can be misleading. Today, - cardiac troponin is still the only marker used routinely in this setting due to - its myocardial tissue specificity and sensitivity, as well as its established - usefulness for therapeutic decision making. However, even current generation - troponin assays have certain limitations such as insufficient sensitivity for - diagnosing unstable angina. Novel high-sensitivity assays for cardiac troponin - have the potential to overcome these limitations. Further studies are needed to - answer some critical questions regarding the best cutoffs for diagnosis and risk - assessment and the optimal work-up for rule-out of acute myocardial infarction. - Other nonmyocardial tissue-specific markers might help in this setting. - Myeloperoxidase, copeptin, and growth differentiation factor 15 reflect different - aspects of the development of atherosclerosis or acute ischemia. Each has - demonstrated impact in risk stratification of acute coronary syndromes. Limited - data also show that copeptin may, when used together with cardiac troponin, - improve the sensitivity for diagnosing acute myocardial infarction, and growth - differentiation factor 15 may help in selection of patients that benefit from - invasive therapy. Further evaluation is needed before these markers can be - adopted routinely in clinical practice. -CI - Copyright © 2010 Mosby, Inc. All rights reserved. -FAU - Hochholzer, Willibald -AU - Hochholzer W -AD - TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and - Women's Hospital, Harvard Medical School, Boston, MA, USA. -FAU - Morrow, David A -AU - Morrow DA -FAU - Giugliano, Robert P -AU - Giugliano RP -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -RN - 0 (Biomarkers) -SB - IM -MH - Biomarkers/*metabolism -MH - Cardiovascular Diseases/*metabolism -MH - Humans -MH - Severity of Illness Index -EDAT- 2010/10/12 06:00 -MHDA- 2010/10/29 06:00 -CRDT- 2010/10/12 06:00 -PHST- 2010/06/07 00:00 [received] -PHST- 2010/06/07 00:00 [accepted] -PHST- 2010/10/12 06:00 [entrez] -PHST- 2010/10/12 06:00 [pubmed] -PHST- 2010/10/29 06:00 [medline] -AID - S0002-8703(10)00498-9 [pii] -AID - 10.1016/j.ahj.2010.06.010 [doi] -PST - ppublish -SO - Am Heart J. 2010 Oct;160(4):583-94. doi: 10.1016/j.ahj.2010.06.010. - -PMID- 17652816 -OWN - NLM -STAT- MEDLINE -DCOM- 20071003 -LR - 20071203 -IS - 1530-7905 (Print) -IS - 1530-7905 (Linking) -VI - 7 -IP - 2 -DP - 2007 -TI - Anthracycline cardiotoxicity in long-term survivors of childhood cancer. -PG - 122-8 -AB - Anthracycline chemotherapy is a widely-used and effective treatment for a wide - spectrum of childhood cancers. Its use is limited by associated progressive and - clinically significant cardiotoxic effects. Onset can be acute, early, or late. - While acute onset is rare, long-term survivors have significantly elevated rates - of cardiac morbidity and mortality. Major complications include cardiomyopathy, - coronary artery disease, and atherosclerosis. Means of prevention and treatment - continue to be explored including limiting cumulative anthracycline dose, - controlling the rate of administration, and using liposomal preparations and - novel anthracycline analogues. Dexrazoxane prior to anthracycline chemotherapy - has been shown to significantly lower rates of elevated serum cardiac troponin - levels, a marker of myocyte injury, indicating a cardioprotective effect. Pilot - studies indicate that exercise interventions may also be beneficial in long-term - survivors with cardiac damage. Support and study of this population to decrease - the morbidity and morality associated with anthracycline-induced cardiotoxicity - is indicated in a time sensitive fashion. -FAU - Scully, Rebecca E -AU - Scully RE -AD - Department of Pediatrics, Division of Pediatric Clinical Research, University of - Miami Miller School of Medicine, Miami, FL 33101, USA. -FAU - Lipshultz, Steven E -AU - Lipshultz SE -LA - eng -GR - CA06516/CA/NCI NIH HHS/United States -GR - CA34183/CA/NCI NIH HHS/United States -GR - CA68484/CA/NCI NIH HHS/United States -GR - CA79060/CA/NCI NIH HHS/United States -GR - HL53392/HL/NHLBI NIH HHS/United States -GR - HL59837/HL/NHLBI NIH HHS/United States -GR - HL69800/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Cardiovasc Toxicol -JT - Cardiovascular toxicology -JID - 101135818 -RN - 0 (Anthracyclines) -RN - 0 (Antibiotics, Antineoplastic) -SB - IM -MH - Anthracyclines/*adverse effects -MH - Antibiotics, Antineoplastic/*adverse effects -MH - Child -MH - Disease Progression -MH - Heart Diseases/*chemically induced/drug therapy/*pathology/prevention & control -MH - Humans -MH - Monitoring, Physiologic -MH - Neoplasms/*complications/drug therapy -MH - Signal Transduction/drug effects -MH - *Survivors -RF - 58 -EDAT- 2007/07/27 09:00 -MHDA- 2007/10/04 09:00 -CRDT- 2007/07/27 09:00 -PHST- 1999/11/30 00:00 [received] -PHST- 1999/11/30 00:00 [revised] -PHST- 1999/11/30 00:00 [accepted] -PHST- 2007/07/27 09:00 [pubmed] -PHST- 2007/10/04 09:00 [medline] -PHST- 2007/07/27 09:00 [entrez] -AID - CT:7:2:122 [pii] -AID - 10.1007/s12012-007-0006-4 [doi] -PST - ppublish -SO - Cardiovasc Toxicol. 2007;7(2):122-8. doi: 10.1007/s12012-007-0006-4. - -PMID- 21476972 -OWN - NLM -STAT- MEDLINE -DCOM- 20111027 -LR - 20191027 -IS - 1875-5453 (Electronic) -IS - 1389-2002 (Linking) -VI - 12 -IP - 6 -DP - 2011 Jul -TI - The roles of cytochrome p450 in ischemic heart disease. -PG - 526-32 -AB - Cytochrome P450 (CYP) represents a large family of enzymes that catalyze the - oxidation of endogenous and exogenous compounds. The functions of CYP enzymes in - the metabolism of xenobiotics have well been established in the liver. However, - some CYP enzymes are highly expressed in the heart and catalyze arachidonic acid - oxidation to a variety of eicosanoids, which attenuates ischemia-reperfusion - injury of the heart. CYP-mediated cardioprotection is associated with activation - of multiple pathways such as sarcolemmal and mitochondrial potassium channels, - p42/p44 MAPK and PI3K-AKT signaling in cells. CYP enzymes also represent a - significant source of reactive oxygen species (ROS) that may target cellular - homeostatic mechanisms and mitochondria. CYP isoforms expressed in the heart are - critical for generation of epoxyeicosatrienoic acids (EETs) and ROS. It has been - demonstrated that CYP2J2 generates cardioprotective EETs, whereas another isozyme - in the heart, CYP2C, generates EETs as well as detrimental ROS. Genetic - polymorphisms of CYP2C or CYP2J2 have a pathologic impact on coronary artery - diseases. Cardiac CYP enzymes can be involved in drug metabolism within the heart - and influence pharmacologic efficacy. Metabolism mediated by CYP enzymes - influences the survival of cardiomyocytes during ischemia, which is critical for - treatment of human ischemic heart disease. In this review, we summarize current - knowledge of this enzyme family and discuss the roles of CYP in - ischemia-reperfusion injury of the heart. -FAU - Sato, Motohiko -AU - Sato M -AD - Cardiovascular Research Institute, Yokohama City University School of Medicine, - Fukuura, Kanazawa-Ku, Japan. motosato@yokohama-cu.ac.jp -FAU - Yokoyama, Utako -AU - Yokoyama U -FAU - Fujita, Takayuki -AU - Fujita T -FAU - Okumura, Satoshi -AU - Okumura S -FAU - Ishikawa, Yoshihioro -AU - Ishikawa Y -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Netherlands -TA - Curr Drug Metab -JT - Current drug metabolism -JID - 100960533 -RN - 0 (Pharmaceutical Preparations) -RN - 0 (Reactive Oxygen Species) -RN - 9035-51-2 (Cytochrome P-450 Enzyme System) -SB - IM -MH - Animals -MH - Cytochrome P-450 Enzyme System/genetics/*metabolism -MH - Humans -MH - Myocardial Ischemia/drug therapy/*enzymology/physiopathology -MH - Myocardial Reperfusion Injury/*enzymology/physiopathology -MH - Myocytes, Cardiac/metabolism -MH - Pharmaceutical Preparations/metabolism -MH - Polymorphism, Genetic -MH - Reactive Oxygen Species/metabolism -EDAT- 2011/04/12 06:00 -MHDA- 2011/10/28 06:00 -CRDT- 2011/04/12 06:00 -PHST- 2011/02/11 00:00 [received] -PHST- 2011/03/25 00:00 [accepted] -PHST- 2011/04/12 06:00 [entrez] -PHST- 2011/04/12 06:00 [pubmed] -PHST- 2011/10/28 06:00 [medline] -AID - BSP/CDM/E-Pub/000160 [pii] -AID - 10.2174/138920011795713715 [doi] -PST - ppublish -SO - Curr Drug Metab. 2011 Jul;12(6):526-32. doi: 10.2174/138920011795713715. - -PMID- 17587733 -OWN - NLM -STAT- MEDLINE -DCOM- 20110613 -LR - 20190819 -IS - 1347-4820 (Electronic) -IS - 1346-9843 (Linking) -VI - 71 Suppl A -DP - 2007 -TI - Risk stratification for sudden cardiac death. -PG - A106-14 -AB - Sudden cardiac death (SCD) is a leading cause of mortality in industrialized - countries, and ventricular fibrillation and sustained ventricular tachycardia are - the major causes of SCD. Although there are now effective devices and medications - that can prevent such serious arrhythmias, it is crucial to have methods of - identifying patients at risk. Numerous studies suggest that most patients dying - of SCD have coronary artery disease or cardiomyopathy. Functional or - electrophysiological measurements are effective in risk stratification. Left - ventricular ejection fraction measured by echocardiography or cardiac imaging - techniques is the gold standard to detect high-risk patients. - Electrophysiological studies have also been used for risk stratification. - Noninvasive techniques and measurements, such as T-wave alternans, - signal-averaged electrocardiography, nonsustained ventricular tachycardia, heart - rate variability, and heart rate turbulence, have been proposed as useful tools - in identifying patients at risk for SCD. This article reviews the epidemiology, - mechanisms, substrates, and current status of risk stratification of SCD. -FAU - Ikeda, Takanori -AU - Ikeda T -AD - Second Department of Internal Medicine, Kyorin University School of Medicine, - Mitaka, Tokyo 181-8611, Japan. iket@kyorin-u.ac.jp -FAU - Yusu, Satoru -AU - Yusu S -FAU - Nakamura, Kentaro -AU - Nakamura K -FAU - Yoshino, Hideaki -AU - Yoshino H -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Japan -TA - Circ J -JT - Circulation journal : official journal of the Japanese Circulation Society -JID - 101137683 -SB - IM -MH - Death, Sudden, Cardiac/epidemiology/*etiology/prevention & control -MH - Evidence-Based Medicine -MH - Heart Diseases/*complications/diagnosis/epidemiology/therapy -MH - Humans -MH - Practice Guidelines as Topic -MH - Predictive Value of Tests -MH - Risk Assessment -MH - Risk Factors -EDAT- 2007/12/06 09:00 -MHDA- 2011/06/15 06:00 -CRDT- 2007/12/06 09:00 -PHST- 2007/12/06 09:00 [pubmed] -PHST- 2011/06/15 06:00 [medline] -PHST- 2007/12/06 09:00 [entrez] -AID - JST.JSTAGE/circj/71.A106 [pii] -AID - 10.1253/circj.71.a106 [doi] -PST - ppublish -SO - Circ J. 2007;71 Suppl A:A106-14. doi: 10.1253/circj.71.a106. - -PMID- 20964114 -OWN - NLM -STAT- MEDLINE -DCOM- 20101129 -LR - 20101022 -IS - 0870-2551 (Print) -IS - 0870-2551 (Linking) -VI - 29 -IP - 6 -DP - 2010 Jun -TI - The reduction of infarct size--forty years of research. -PG - 1037-53 -AB - Advances in electrocardiography and enzymology in the 1940s and 1950s have - provided better knowledge of the clinical evolution of myocardial infarction and - recognition of the prognostic relevance of acute phase arrhythmias. This prompted - the creation of intensive coronary care units in the subsequent decade. After the - successful resolution of acute phase arrhythmias, it became clear that the - myocardium necrotic area size was a determining factor in the long-term - prognosis. The Killip-Kimball clinical classification in the 60s helped to - clarify the role of infarct size on left ventricle (LV) dysfunction, from Class I - for small infarcts to Class IV with major necrosis, (involving more than 30% of - the LV free wall area, the majority of these being fatal). Along with these - advances, a series of experimental studies have shown that myocardial ischemia - depends on the oxygen supply-demand imbalance, highlighting the factors affecting - oxygen consumption. The study of various physiological, pharmacological or - mechanical interventions on these factors became the next step towards optimizing - the supply-demand relation. Several animal experiments were conducted in the - 1970s, followed by the first clinical studies to reduce infarct size, - particularly by increasing the oxygen supply either with fibrinolytic agents or - with mechanical coronary angioplasty. The clinical experience of coronary - reperfusion showed that left ventricle function did not normalize in 30% of the - patients. In spite of unblocking the epicardial vessel, demonstrated - hemodynamically, no equivalent myocardial perfusion was observed in these - studies. New concepts emerged such as reperfusion injury, microvascular - dysfunction, "no-reflow" phenomenon, stunned myocardium, and hibernating - myocardium, which have become the target of basic research and clinical - investigation. The replication of these phenomena in experimental models has - attempted on the one hand to improve characterization with the use of different - technologies, e.g. contrast echocardiography, isotopic studies including positron - tomography, and magnetic resonance. On the other hand it has tested new - therapeutic approaches as adjuvants of coronary reperfusion. Reperfusion injury - is responsible for 50% of infarct size, so it became the target of research on - cardiac protection. Post-reperfusion arrhythmias, stunned myocardium, - microvascular obstruction that translates into the "no-reflow" phenomenon, are - reperfusion injury manifestations. Imaging technology developments made it - possible to demonstrate that microvascular obstruction occurs in 40% of patients - who underwent primary angioplasty. Several therapeutic approaches to prevent - microembolization have been studied such as glycoprotein IIb/IIIa receptor - blockers. Ischemic myocardium conditioning is one of the new strategies to reduce - reperfusion injury. The concept of pre-conditioning, defined experimentally in - 1986, establishes that multiple brief episodes of ischemia may protect the heart - from a subsequent prolonged infarction. Several observations have proved that - pre-conditioning occurs in cardiac patients, for example, during coronary - angioplasty and coronary bypass graft surgery, and so it is regarded as a - promising approach to reducing infarct size. The concept of pre-conditioning was - then enlarged by the demonstration, experimentally, that producing ischemia in a - vascular bed could induce pre-conditioning in another vascular bed. Ischemia - resulting from repeated successive insufflations of a blood pressure cuff on a - lim, reduces myocardial necrosis after coronary angioplasty or coronary bypass - graft surgery. This remote pre-conditioning seems to be a safe and effective - non-invasive way of reducing the reperfusion injury. In 2002 a hypothesis was - tested in studies on dogs that multiple repeated episodes of ischemia, produced - in the beginning of reperfusion, would attenuate the reperfusion injury. This - technique, called post-conditioning, was first used in patients in 2005, in AMI - reperfusion, with beneficial short and long-term results. In the last 15 years, a - large number of clinical studies have been carried with different pharmacologic - groups to explore association pre- and post-conditioning concepts. Four agents - were studied in particular: adenosine, nicorandil, atrial natriuretic peptide, - and statins. The most important studies are reviewed, calling attention to - disparities in results and discussing possible causes of negative outcomes. - Cyclosporine, recently tested, opens a new field of investigation since it - inhibits mitochondrial permeability and may directly attenuate the reperfusion - injury. Microvascular dysfunction occurs in many patients after coronary - angioplasty and is caused, in the first place, by distal embolization. The - purpose of thrombectomy is to reduce the probability of distal embolization - during angioplasty and stent placement. Available devices for clinical use - include thrombus aspiration and thrombectomy catheters. Initial studies did not - have the expected impact, but the number of patients studied was limited. A - recent series involving more than 1000 AMI patients undergoing coronary - angioplasty and thrombus aspiration has shown an improvement of myocardial - perfusion indices and a reduction of mortality at 30 days. Distal embolization - protection systems aim to prevent the embolic material entering the circulation - and causing macro-or microembolization. The present small and controversial - experience does not yet recommend the routine use of this technique. Reduction of - infarct size has been the main objective of research on ischemic myocardial - disease during the last 40 years. Myocardial reperfusion is a major - accomplishment in this field. But it is like a double-edged sword because - reperfusion injury significantly reduces the potential benefits of reperfusion. - The huge amount of research undertaken in the past 20 years constitutes a - paradigm of the relationship between experimental work and clinical practice, and - has improved the prospects for diminishing infarct size, in both the short and - long-term. -FAU - Ferreira, Rafael -AU - Ferreira R -AD - Faculdade de Medicina de Lisboa. prof.rafaelferreira@sapo.pt -LA - eng -LA - por -PT - Journal Article -PT - Review -PL - Portugal -TA - Rev Port Cardiol -JT - Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de - Cardiologia = Portuguese journal of cardiology : an official journal of the - Portuguese Society of Cardiology -JID - 8710716 -SB - IM -MH - Biomedical Research -MH - Humans -MH - Myocardial Stunning/*pathology -MH - Time Factors -EDAT- 2010/10/23 06:00 -MHDA- 2010/12/14 06:00 -CRDT- 2010/10/23 06:00 -PHST- 2010/10/23 06:00 [entrez] -PHST- 2010/10/23 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -PST - ppublish -SO - Rev Port Cardiol. 2010 Jun;29(6):1037-53. - -PMID- 16568192 -OWN - NLM -STAT- MEDLINE -DCOM- 20060511 -LR - 20071115 -IS - 0027-2507 (Print) -IS - 0027-2507 (Linking) -VI - 73 -IP - 2 -DP - 2006 Mar -TI - Approach to undifferentiated chest pain in the emergency department: a review of - recent medical literature and published practice guidelines. -PG - 499-505 -AB - Chest pain is the presenting complaint in over 6 million emergency department - visits each year. Differentiating acute coronary syndrome (ACS) from other, - noncardiac causes of chest pain is imperative in emergency practice. This article - reviews the current medical evidence and published guidelines for the diagnosis - of undifferentiated chest pain. A MEDLINE database search was conducted for - relevant English language articles discussing an approach to undifferentiated - chest pain. The published guidelines of the American College of Emergency - Physicians, the American Heart Association, and the American College of - Cardiology were also reviewed. The data surveyed suggest that, for all adult - patients complaining of nontraumatic chest pain, a cardiac etiology for their - presentation should be considered. History, physical examination, - electrocardiogram, chest radiography, and to a lesser extent laboratory results - can help differentiate ACS from other emergent diagnoses, e.g., aortic - dissection, esophageal rupture, pulmonary embolus, pneumothorax, pneumonia, and - pericarditis. No single feature of a patient's history, physical examination, or - diagnostic test results can diagnose ACS to the exclusion of other causes of - chest pain. Consequently, patients presenting with a complaint of chest pain - frequently require serial evaluations, and admission to an observation unit or - the hospital. -FAU - Ringstrom, Elin -AU - Ringstrom E -AD - Department of Emergency Medicine, Box 1149, Mount Sinai School of Medicine, One - East 100th Street, New York, NY 10029, USA. -FAU - Freedman, Jessica -AU - Freedman J -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Mt Sinai J Med -JT - The Mount Sinai journal of medicine, New York -JID - 0241032 -SB - IM -MH - Acute Disease -MH - Chest Pain/*diagnosis/etiology -MH - Emergency Service, Hospital/*standards -MH - *Evidence-Based Medicine -MH - Heart Diseases/diagnosis/physiopathology -MH - Humans -MH - Observation -MH - *Practice Guidelines as Topic -RF - 60 -EDAT- 2006/03/29 09:00 -MHDA- 2006/05/12 09:00 -CRDT- 2006/03/29 09:00 -PHST- 2006/03/29 09:00 [pubmed] -PHST- 2006/05/12 09:00 [medline] -PHST- 2006/03/29 09:00 [entrez] -PST - ppublish -SO - Mt Sinai J Med. 2006 Mar;73(2):499-505. - -PMID- 17143038 -OWN - NLM -STAT- MEDLINE -DCOM- 20070322 -LR - 20181201 -IS - 0268-4705 (Print) -IS - 0268-4705 (Linking) -VI - 22 -IP - 1 -DP - 2007 Jan -TI - Cost-effectiveness of automated external defibrillators in public places: con. -PG - 5-10 -AB - PURPOSE OF REVIEW: To discuss the clinical effectiveness, public health impact - and cost-effectiveness of public access defibrillation. RECENT FINDINGS: High - rates of survival from prehospital ventricular fibrillation have been documented - in patients treated by first responders using automated external defibrillators. - The recent Public Access Defibrillation trial demonstrated a doubling of cardiac - arrest survival in community units where volunteers trained in cardiopulmonary - resuscitation were additionally equipped with automated external defibrillators. - The cost-effectiveness analysis of the Public Access Defibrillation trial has not - yet been published, and previous analyses have lacked full data on cost, outcome, - or both. Data from many sources indicate that automated external defibrillator - placement at sites with an expected rate of one cardiac arrest per defibrillator - per 5 years, as recommended by the American Heart Association, addresses only - around 1-2% of prehospital arrests, and will have a minimal impact on population - survival. SUMMARY: While highly targeted provision of automated external - defibrillators in areas of greatest risk, such as casinos and airports, may be - cost-effective, it will have little impact at a population level. Provision of - more widespread public access defibrillation to sites with lower incidence of - cardiac arrest is unlikely to be cost-effective, and may represent poorer value - for money than alternative healthcare interventions in coronary artery disease. -FAU - Pell, Jill P -AU - Pell JP -AD - University of Glasgow, Scotland, UK. -FAU - Walker, Andrew -AU - Walker A -FAU - Cobbe, Stuart M -AU - Cobbe SM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -SB - IM -CIN - Curr Opin Cardiol. 2007 Jan;22(1):1-4. doi: 10.1097/HCO.0b013e32801173c1. PMID: - 17143037 -MH - Cost-Benefit Analysis -MH - Defibrillators/*economics/statistics & numerical data -MH - Emergency Treatment/economics -MH - Heart Arrest/*economics/therapy -MH - Humans -MH - *Public Facilities -MH - Resuscitation/economics -RF - 51 -EDAT- 2006/12/05 09:00 -MHDA- 2007/03/23 09:00 -CRDT- 2006/12/05 09:00 -PHST- 2006/12/05 09:00 [pubmed] -PHST- 2007/03/23 09:00 [medline] -PHST- 2006/12/05 09:00 [entrez] -AID - 00001573-200701000-00003 [pii] -AID - 10.1097/HCO.0b013e3280118fec [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2007 Jan;22(1):5-10. doi: 10.1097/HCO.0b013e3280118fec. - -PMID- 24274646 -OWN - NLM -STAT- MEDLINE -DCOM- 20140929 -LR - 20140116 -IS - 1744-7607 (Electronic) -IS - 1742-5255 (Linking) -VI - 10 -IP - 2 -DP - 2014 Feb -TI - Cytochrome P450 and ischemic heart disease: current concepts and future - directions. -PG - 191-213 -LID - 10.1517/17425255.2014.859675 [doi] -AB - INTRODUCTION: The P450 enzymes (P450s) mediate the biotransformation of several - drugs, steroid hormones, eicosanoids, cholesterol, vitamins, fatty acids and bile - acids, many of which affect cardiovascular homeostasis. Experimental studies have - demonstrated that several P450s modulate important steps in the pathogenesis of - ischemic heart disease (IHD). AREAS COVERED: This article discusses the current - knowledge on i) the expression of P450s in cardiovascular and renal tissues; ii) - the role of P450s in the pathophysiology of IHD, in particular the modulation of - blood pressure and cardiac hypertrophy, coronary arterial tone, - ischemia-reperfusion injury and the metabolism of cardiovascular drugs; iii) the - available evidence from observational studies on the association between P450 - gene polymorphisms and risk of myocardial infarction (MI); and iv) suggestions - for further research in this area. EXPERT OPINION: P450s exert important - modulatory effects in experimental models of IHD and MI. However, observational - studies have provided conflicting results on the association between P450 genetic - polymorphisms and MI. Further, adequately powered studies are required to - ascertain the biological and clinical impact of P450s on clinical IHD end-points, - that is, fatal and nonfatal MI, revascularization and long-term outcomes post MI. - Pharmacogenetic substudies of recently completed cardiovascular clinical trials - might represent an alternative strategy in this context. -FAU - Rowland, Andrew -AU - Rowland A -AD - Flinders University, School of Medicine, Department of Clinical Pharmacology , - Bedford Park, SA 5042 , Australia. -FAU - Mangoni, Arduino A -AU - Mangoni AA -LA - eng -PT - Journal Article -PT - Review -DEP - 20131125 -PL - England -TA - Expert Opin Drug Metab Toxicol -JT - Expert opinion on drug metabolism & toxicology -JID - 101228422 -RN - 0 (Cardiovascular Agents) -RN - 9035-51-2 (Cytochrome P-450 Enzyme System) -SB - IM -MH - Animals -MH - Cardiovascular Agents/metabolism/pharmacology/*therapeutic use -MH - Cytochrome P-450 Enzyme System/*biosynthesis -MH - Forecasting -MH - Humans -MH - Kidney/drug effects/enzymology -MH - Myocardial Ischemia/*drug therapy/*enzymology -MH - Myocardium/enzymology -EDAT- 2013/11/28 06:00 -MHDA- 2014/09/30 06:00 -CRDT- 2013/11/27 06:00 -PHST- 2013/11/27 06:00 [entrez] -PHST- 2013/11/28 06:00 [pubmed] -PHST- 2014/09/30 06:00 [medline] -AID - 10.1517/17425255.2014.859675 [doi] -PST - ppublish -SO - Expert Opin Drug Metab Toxicol. 2014 Feb;10(2):191-213. doi: - 10.1517/17425255.2014.859675. Epub 2013 Nov 25. - -PMID- 22401930 -OWN - NLM -STAT- MEDLINE -DCOM- 20130206 -LR - 20151119 -IS - 1873-0183 (Electronic) -IS - 1568-9972 (Linking) -VI - 11 -IP - 12 -DP - 2012 Oct -TI - B-type natriuretic peptide in rheumatic diseases: a cardiac biomarker or a - sophisticated acute phase reactant? -PG - 837-43 -LID - S1568-9972(12)00046-8 [pii] -LID - 10.1016/j.autrev.2012.02.018 [doi] -AB - Natriuretic peptides (NP) are secreted by cardiomyocytes and are reliable markers - of cardiac dysfunction and cardiovascular risk by reflecting myocardial stress - due to various etiologies. Clinical and occult heart involvement is frequently - observed in patients with rheumatic diseases and is associated with increased - morbidity and mortality. Cardiac disease in autoimmune disorders encompasses - different pathophysiological mechanisms including inflammation and involving - either the myocardium or the coronary/pulmonary vessels. Although the major - trigger for the synthesis and release of NP is myocardial strain, there is also - some support for the concept that inflammation stimulates the neurohormonal - system of the heart leading to increased production of NP. Recent studies have - focused on the association of NP and inflammation in the context of rheumatic - diseases, suggesting that up-regulation of neurohormonal axis in these conditions - is linked with inflammation. Additionally the NP have a well-documented role in - the diagnostic work-up of patients with connective tissue disease who are at - increased risk of developing pulmonary hypertension, as the right ventricular - overload results in increased NP synthesis and release. However the precise role - of NP in the assessment and the management of cardiovascular risk in patients - with rheumatic diseases is yet to be established. In the current article we - discuss the pathophysiologic mechanisms involved in enhanced NP expression in - patients with rheumatic disorders and their potential clinical implication in - daily practice. -CI - Copyright © 2012 Elsevier B.V. All rights reserved. -FAU - Dimitroulas, Theodoros -AU - Dimitroulas T -AD - Department of Rheumatology, Dudley Group NHS Foundation Trust, Russells Hall - Hospital, Dudley, West Midlands DY1 2LT, UK. dimitroul@hotmail.com -FAU - Giannakoulas, George -AU - Giannakoulas G -FAU - Karvounis, Haralambos -AU - Karvounis H -FAU - Garyfallos, Alexandros -AU - Garyfallos A -FAU - Settas, Lukas -AU - Settas L -FAU - Kitas, George -AU - Kitas G -LA - eng -PT - Journal Article -PT - Review -DEP - 20120228 -PL - Netherlands -TA - Autoimmun Rev -JT - Autoimmunity reviews -JID - 101128967 -RN - 0 (Biomarkers) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Acute-Phase Reaction/*diagnosis -MH - Animals -MH - Biomarkers/metabolism -MH - Cardiovascular Diseases/complications/*diagnosis/physiopathology -MH - Diagnosis, Differential -MH - Humans -MH - Natriuretic Peptide, Brain/*metabolism -MH - Prognosis -MH - Rheumatic Diseases/complications/*diagnosis/physiopathology -MH - Risk -EDAT- 2012/03/10 06:00 -MHDA- 2013/02/07 06:00 -CRDT- 2012/03/10 06:00 -PHST- 2012/02/08 00:00 [received] -PHST- 2012/02/20 00:00 [accepted] -PHST- 2012/03/10 06:00 [entrez] -PHST- 2012/03/10 06:00 [pubmed] -PHST- 2013/02/07 06:00 [medline] -AID - S1568-9972(12)00046-8 [pii] -AID - 10.1016/j.autrev.2012.02.018 [doi] -PST - ppublish -SO - Autoimmun Rev. 2012 Oct;11(12):837-43. doi: 10.1016/j.autrev.2012.02.018. Epub - 2012 Feb 28. - -PMID- 18926169 -OWN - NLM -STAT- MEDLINE -DCOM- 20081113 -LR - 20250529 -IS - 1555-7162 (Electronic) -IS - 0002-9343 (Print) -IS - 0002-9343 (Linking) -VI - 121 -IP - 10 Suppl 1 -DP - 2008 Oct -TI - Cardiovascular morbidity and mortality in rheumatoid arthritis. -PG - S9-14 -LID - 10.1016/j.amjmed.2008.06.011 [doi] -AB - Patients with rheumatoid arthritis (RA) are at increased risk of mortality - compared with the general population. Evidence suggests that this increased - mortality can largely be attributed to increased cardiovascular (CV) death. In a - retrospective study of an inception cohort of RA patients in Rochester, MN, we - found that patients with RA were at increased risk of CV death, ischemic heart - disease, and heart failure compared with age- and sex-matched community controls. - In addition, when we examined coronary artery tissue from autopsied RA patients, - we observed increased evidence of inflammation and an increased proportion of - unstable plaques. We also investigated the contribution of traditional and - RA-specific risk factors to this increased risk of CV morbidity and mortality. - Although traditional CV disease risk factors were found to contribute to the - increased risk of mortality in RA patients, they did not fully explain the - increased CV mortality observed in RA. Instead, increased inflammation associated - with RA appears to contribute substantially to the increased CV mortality. - Together with other studies that have demonstrated similar associations between - RA and CV mortality, these data suggest that more aggressive management of - inflammation in RA may lead to significant improvements in outcomes for patients - with RA. -FAU - Gabriel, Sherine E -AU - Gabriel SE -AD - Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, - USA. gabriel@mayo.edu -LA - eng -GR - R01 AR030582/AR/NIAMS NIH HHS/United States -GR - R01 AR046849/AR/NIAMS NIH HHS/United States -GR - R01 AR46849/AR/NIAMS NIH HHS/United States -GR - AR-30582/AR/NIAMS NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - Am J Med -JT - The American journal of medicine -JID - 0267200 -SB - IM -MH - Arthritis, Rheumatoid/*complications -MH - Cardiovascular Diseases/*epidemiology/etiology -MH - Humans -MH - Morbidity -MH - Risk Factors -MH - Survival Rate -MH - United States/epidemiology -PMC - PMC2858687 -MID - NIHMS185402 -EDAT- 2008/10/24 09:00 -MHDA- 2008/11/14 09:00 -PMCR- 2010/04/22 -CRDT- 2008/10/24 09:00 -PHST- 2008/10/24 09:00 [pubmed] -PHST- 2008/11/14 09:00 [medline] -PHST- 2008/10/24 09:00 [entrez] -PHST- 2010/04/22 00:00 [pmc-release] -AID - S0002-9343(08)00590-1 [pii] -AID - 10.1016/j.amjmed.2008.06.011 [doi] -PST - ppublish -SO - Am J Med. 2008 Oct;121(10 Suppl 1):S9-14. doi: 10.1016/j.amjmed.2008.06.011. - -PMID- 16611079 -OWN - NLM -STAT- MEDLINE -DCOM- 20060620 -LR - 20190823 -IS - 0929-8673 (Print) -IS - 0929-8673 (Linking) -VI - 13 -IP - 9 -DP - 2006 -TI - Pharmaceutical interventions to influence arteriogenesis: new concepts to treat - ischemic heart disease. -PG - 979-87 -AB - Despite the technical progress in interventional techniques to overcome the - harmful effects of ischemic heart disease there is still an urgent need for - alternative, pharmaceutical treatment modalities. Exogenous stimulation of vessel - growth, i.e. vasculogenesis, angiogenesis or arteriogenesis serves as a promising - strategy to restore blood flow to the jeopardized tissue regions downstream of - arterial stenosis or occlusion. While vasculogenesis is defined as the - arrangement of angioblasts during prenatal development creating the first - vascular network, angiogenesis and arteriogenesis refer to important adaptive - mechanisms in the adult organism. Angiogenesis, neo-formation of capillaries, is - a key process in many different physiological and pathophysiological events where - improvement of microvascular function and tissue nutrition is needed (e.g. wound - healing, tumor growth). In contrast to this capillary sprouting, the term - arteriogenesis refers to the development of large caliber collateral arteries. - Under conditions of increasing shear stress, anastomoses between interconnected - perfusion territories can undergo adaptive enlargement, developing into a - functional network of collateral arteries, natural bypasses able to maintain - sufficient blood flow and compensating for the gradual occlusion of a large - artery (e.g. in the coronary circulation). However, in most cases arteriogenesis - does not proceed as fast as the stenosis progresses and infarction and tissue - necrosis results. A well-developed collateral network is an important protective - factor for the occurrence of ischemic events and therefore pharmaceutical - acceleration and stimulation of arteriogenesis in patients represents an eminent - aim for the future. This review focuses on the basic mechanisms of - arteriogenesis, the recent progresses in translating these insights into the - clinical situation and the problems yet to be solved. -FAU - Hoefer, Imo E -AU - Hoefer IE -AD - Dept. of Experimental Cardiology, UMC Utrecht, Netherlands. - i.hoefer@umcutrecht.nl -FAU - Piek, Jan J -AU - Piek JJ -FAU - Pasterkamp, Gerard -AU - Pasterkamp G -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Angiogenesis Inducing Agents) -SB - IM -MH - Angiogenesis Inducing Agents/*therapeutic use -MH - Humans -MH - Myocardial Ischemia/*drug therapy/pathology -MH - Neovascularization, Physiologic/*drug effects -RF - 105 -EDAT- 2006/04/14 09:00 -MHDA- 2006/06/21 09:00 -CRDT- 2006/04/14 09:00 -PHST- 2006/04/14 09:00 [pubmed] -PHST- 2006/06/21 09:00 [medline] -PHST- 2006/04/14 09:00 [entrez] -AID - 10.2174/092986706776360996 [doi] -PST - ppublish -SO - Curr Med Chem. 2006;13(9):979-87. doi: 10.2174/092986706776360996. - -PMID- 23540744 -OWN - NLM -STAT- MEDLINE -DCOM- 20130520 -LR - 20241217 -IS - 1532-8708 (Electronic) -IS - 0093-7754 (Linking) -VI - 40 -IP - 2 -DP - 2013 Apr -TI - Strategies to prevent and treat cardiovascular risk in cancer patients. -PG - 186-98 -LID - S0093-7754(13)00009-2 [pii] -LID - 10.1053/j.seminoncol.2013.01.008 [doi] -AB - Cardiotoxicity due to cancer treatment is of rising concern, for both - cardiologists and oncologists, because it may have a significant impact on cancer - patient management and outcome. The most typical manifestation of cardiotoxicity - is a hypokinetic cardiomyopathy leading to heart failure. However, the spectrum - of the toxic effects that can impair the cardiovascular system may also include - acute coronary syndromes, hypertension, arrhythmias, and thromboembolic events. - Patients undergoing cancer treatment are more vulnerable to cardiovascular - injuries, and their risk of premature cardiovascular disease and death is higher - than that of the general population. Prevention of cardiotoxicity remains the - most important strategy, and several measures, including cardiac function - monitoring, limitation of chemotherapy dose, use of anthracycline analogues and - cardioprotectants, and early detection of myocardial cell injury by biomarkers, - have been proposed. The response to modern heart failure therapy of cancer - treatment-induced cardiomyopathy has never been evaluated in clinical trials, and - currently there are no definitive guidelines. Although it is likely that - medications used for other forms of cardiomyopathy, particularly - angiotensin-converting enzyme inhibitors and β-blockers, may be highly effective, - there is still some unjustified concern regarding their use in cancer patients. - Specific guidelines that take cardiologic conditions of cancer patients into - account are currently lacking and need to be developed. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Cardinale, Daniela -AU - Cardinale D -AD - Cardioncology Unit, European Institute of Oncology, Milan, Italy. - daniela.cardinale@ieo.it -FAU - Bacchiani, Giulia -AU - Bacchiani G -FAU - Beggiato, Marta -AU - Beggiato M -FAU - Colombo, Alessandro -AU - Colombo A -FAU - Cipolla, Carlo M -AU - Cipolla CM -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Semin Oncol -JT - Seminars in oncology -JID - 0420432 -RN - 0 (Antineoplastic Agents) -RN - 0 (Biomarkers) -RN - 0 (Cardiotonic Agents) -RN - 0 (Troponin) -SB - IM -MH - Animals -MH - Antineoplastic Agents/*adverse effects/therapeutic use -MH - Biomarkers/metabolism -MH - Cardiotonic Agents/therapeutic use -MH - Cardiovascular Diseases/chemically induced/diagnosis/physiopathology/*prevention - & control -MH - Disease Management -MH - Early Diagnosis -MH - Humans -MH - Neoplasms/*drug therapy -MH - Risk Factors -MH - Stroke Volume/drug effects -MH - Troponin/metabolism -EDAT- 2013/04/02 06:00 -MHDA- 2013/05/22 06:00 -CRDT- 2013/04/02 06:00 -PHST- 2013/04/02 06:00 [entrez] -PHST- 2013/04/02 06:00 [pubmed] -PHST- 2013/05/22 06:00 [medline] -AID - S0093-7754(13)00009-2 [pii] -AID - 10.1053/j.seminoncol.2013.01.008 [doi] -PST - ppublish -SO - Semin Oncol. 2013 Apr;40(2):186-98. doi: 10.1053/j.seminoncol.2013.01.008. - -PMID- 19049692 -OWN - NLM -STAT- MEDLINE -DCOM- 20090323 -LR - 20250623 -IS - 2046-4924 (Electronic) -IS - 1366-5278 (Linking) -VI - 12 -IP - 36 -DP - 2008 Dec -TI - Immunoprophylaxis against respiratory syncytial virus (RSV) with palivizumab in - children: a systematic review and economic evaluation. -PG - iii, ix-x, 1-86 -AB - OBJECTIVES: To systematically review the effectiveness and cost-effectiveness of - palivizumab for the prevention of respiratory syncytial virus (RSV) in children - and examine prognostic factors to determine whether subgroups can be identified - with important differences in cost-effectiveness. DATA SOURCES: Bibliographic - databases were searched from inception to March 2007 for literature on the - effectiveness and cost-effectiveness of prophylaxis with palivizumab. REVIEW - METHODS: The literature was systematically reviewed and current economic - evaluations were analysed to identify which parameters were driving the different - cost-effectiveness estimates. A probabilistic decision-analytical model was built - to assess the cost-effectiveness of prophylaxis with palivizumab for children at - risk of RSV infection and the parameters populated with the best estimates - thought most applicable to the UK. We also constructed a new model, the - Birmingham Economic Evaluation (BrumEE). Cost-effectiveness analyses were - undertaken from both NHS and societal perspectives. RESULTS: Two randomised - controlled trials (RCTs) were identified. Prophylaxis with palivizumab for - preterm infants without chronic lung disease (CLD) or children with CLD resulted - in a 55% reduction in RSV hospital admission: 4.8% (48/1002) in the palivizumab - group and 10.6% (53/500) in the no prophylaxis group (p = 0.0004). Prophylaxis - with palivizumab was associated with a 45% reduction in hospitalisation rate RSV - among children with coronary heart disease (CHD). Hospitalisation rates for RSV - were 5.3% (34/639) in the palivizumab group and 9.7% (63/648) in the no - prophylaxis group (p = 0.003). Of existing economic evaluations, 3 systematic - reviews and 18 primary studies were identified. All the systematic reviews - concluded that the potential costs of palivizumab were far in excess of any - potential savings achieved by decreasing hospital admission rates, and that the - use of palivizumab was unlikely to be cost-effective in all children for whom it - is recommended, but that its continued use for particularly high-risk children - may be justified. The incremental cost-effectiveness ratios (ICERs) of the - primary studies varied 17-fold for life-years gained (LYG), from 25,800 - pounds/LYG to 404,900 pounds/LYG, and several hundred-fold for quality-adjusted - life-years (QALYs), from 3200 pounds/QALY to 1,489,700 pounds/QALY for preterm - infants without CLD or children with CLD. For children with CHD, the ICER varied - from 5300 pounds/LYG to 7900 pounds/LYG and from 7500 pounds/QALY to 68,700 - pounds/QALY. An analysis of what led to the discrepant ICERs showed that the - assumed mortality rate for RSV infection was the most important driver. The - results of the BrumEE confirm that palivizumab does not reach conventional levels - of cost-effectiveness in any of the licensed indications if used for all eligible - children. CONCLUSIONS: Prophylaxis with palivizumab is clinically effective for - the reducing the risk of serious lower respiratory tract infection caused by RSV - infection and requiring hospitalisation in high-risk children, but if used - unselectively in the licensed population, the ICER is double that considered to - represent good value for money in the UK. The BrumEE shows that prophylaxis with - palivizumab may be cost-effective (based on a threshold of 30,000 pounds/QALY) - for children with CLD when the children have two or more additional risk factors. - Future research should initially focus on reviewing systematically the major - uncertainties for patient subgroups with CLD and CHD and then on primary research - to address the important uncertainties that remain. -FAU - Wang, D -AU - Wang D -AD - Department of Public Health and Epidemiology, University of Birmingham, - Birmingham, UK. -FAU - Cummins, C -AU - Cummins C -FAU - Bayliss, S -AU - Bayliss S -FAU - Sandercock, J -AU - Sandercock J -FAU - Burls, A -AU - Burls A -LA - eng -PT - Journal Article -PT - Systematic Review -PL - England -TA - Health Technol Assess -JT - Health technology assessment (Winchester, England) -JID - 9706284 -RN - 0 (Antibodies, Monoclonal) -RN - 0 (Antibodies, Monoclonal, Humanized) -RN - 0 (Antiviral Agents) -RN - DQ448MW7KS (Palivizumab) -SB - IM -MH - Antibodies, Monoclonal/administration & dosage/economics/immunology/*therapeutic - use -MH - Antibodies, Monoclonal, Humanized -MH - Antiviral Agents/administration & dosage/economics/immunology/*therapeutic use -MH - Evidence-Based Medicine -MH - Humans -MH - Infant -MH - Infant, Newborn -MH - Palivizumab -MH - Preventive Medicine/*economics -MH - Respiratory Syncytial Virus Infections/economics/immunology/*prevention & control -MH - Respiratory Syncytial Viruses/drug effects/*immunology -MH - United Kingdom -RF - 79 -EDAT- 2008/12/04 09:00 -MHDA- 2009/03/24 09:00 -CRDT- 2008/12/04 09:00 -PHST- 2008/12/04 09:00 [pubmed] -PHST- 2009/03/24 09:00 [medline] -PHST- 2008/12/04 09:00 [entrez] -AID - 06/29/01 [pii] -AID - 10.3310/hta12360 [doi] -PST - ppublish -SO - Health Technol Assess. 2008 Dec;12(36):iii, ix-x, 1-86. doi: 10.3310/hta12360. - -PMID- 17339573 -OWN - NLM -STAT- MEDLINE -DCOM- 20070327 -LR - 20070306 -IS - 1524-4539 (Electronic) -IS - 0009-7322 (Linking) -VI - 115 -IP - 9 -DP - 2007 Mar 6 -TI - Hemiblocks revisited. -PG - 1154-63 -AB - The trifascicular nature of the intraventricular conduction system and the - concept of trifascicular block and hemiblock were described by Rosenbaum and his - coworkers in 1968. Since then, anatomic, pathological, electrophysiological, and - clinical studies have confirmed the original description and scarce advances have - been developed on the subject. In the present study, we attempt to review and - redefine reliable criteria for the electrocardiographic and vectorcardiographic - diagnosis of left anterior and posterior hemiblock. One of the most important - problems related to hemiblocks is that they may simulate or conceal the - electrocardiographic signs of myocardial infarction or myocardial ischemia and - may mask or simulate ventricular hypertrophy. Illustrative examples of these - associations are shown to help the interpretation of electrocardiograms. The - incidence and prevalence of the hemiblocks is presented based on studies - performed in hospital patients and general populations. One of the most common - causes of hemiblocks is coronary artery disease, and there is a particularly - frequent association between anteroseptal myocardial infarction and left anterior - hemiblock. The second most important cause is arterial hypertension, followed by - cardiomyopathies and Lev and Lenègre diseases. The hemiblocks may also occur in - aortic heart disease and congenital cardiopathies. Left anterior hemiblock is - more common in men and increases in frequency with advancing age. Evidence is - presented regarding the relationship of spontaneous closure of ventricular septal - defects, which may explain the finding of this and other conduction defects in - young populations. Isolated left anterior hemiblock is a relatively frequent - finding in subjects devoid of evidence of structural heart disease. Conversely, - isolated left posterior hemiblock is a very rare finding; its prognostic - significance is unknown and is commonly associated with right bundle-branch - block. The most remarkable feature of this association is that the prognosis is - much more serious with a great propensity to develop complete atrioventricular - block and Adams-Stoke seizures. -FAU - Elizari, Marcelo V -AU - Elizari MV -AD - Division of Cardiology, Ramos Mejía Hospital, Urquiza 609, Buenos Aires C1221ADC, - Argentina. elizarimv@fibertel.com.ar -FAU - Acunzo, Rafael S -AU - Acunzo RS -FAU - Ferreiro, Marcela -AU - Ferreiro M -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Circulation -JT - Circulation -JID - 0147763 -SB - IM -MH - Adams-Stokes Syndrome/etiology -MH - Adolescent -MH - Adult -MH - Aged -MH - Bundle-Branch Block/complications/diagnosis/physiopathology -MH - Diagnostic Errors -MH - *Electrocardiography -MH - Female -MH - Heart Block/classification/complications/*diagnosis/epidemiology/physiopathology -MH - Heart Conduction System/anatomy & histology/physiopathology -MH - Humans -MH - Hypertrophy, Left Ventricular/complications/diagnosis -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/complications/diagnosis -MH - Prevalence -MH - Prognosis -MH - Retrospective Studies -MH - *Vectorcardiography -RF - 46 -EDAT- 2007/03/07 09:00 -MHDA- 2007/03/28 09:00 -CRDT- 2007/03/07 09:00 -PHST- 2007/03/07 09:00 [pubmed] -PHST- 2007/03/28 09:00 [medline] -PHST- 2007/03/07 09:00 [entrez] -AID - 115/9/1154 [pii] -AID - 10.1161/CIRCULATIONAHA.106.637389 [doi] -PST - ppublish -SO - Circulation. 2007 Mar 6;115(9):1154-63. doi: 10.1161/CIRCULATIONAHA.106.637389. - -PMID- 21484526 -OWN - NLM -STAT- MEDLINE -DCOM- 20111114 -LR - 20211203 -IS - 1937-5395 (Electronic) -IS - 1937-5387 (Linking) -VI - 4 -IP - 4 -DP - 2011 Aug -TI - In vivo imaging and computational analysis of the aortic root. Application in - clinical research and design of transcatheter aortic valve systems. -PG - 459-69 -LID - 10.1007/s12265-011-9277-z [doi] -AB - Valvular heart disease is a major cause of morbidity and mortality in developing - and industrialized countries. For patients with advanced symptomatic disease, - surgical open-heart valve replacement is an effective treatment, supported by - long-term outcome data. More recently, less-invasive transcatheter approaches for - valve replacement/implantation have been developed for patients that are not - considered surgical candidates. An understanding of valvular and paravalvular - anatomy and biomechanics is pivotal for the optimization of interventional valve - procedures. Advanced imaging is increasingly used not only for clinical guidance - but also for the design and further improvement of transcatheter valve systems. - Computed tomography is particularly attractive because it acquires - high-resolution volumetric data sets of the root including the leaflets and - coronary artery ostia, with sufficient temporal resolution for multi-phasic - analysis. These volumetric data sets allow subsequent 3-D and 4-D display, - reconstruction in unlimited planes, and mathematical modeling. Computer modeling, - specifically finite element analysis, of devices intended for implantation in the - aortic root, allows for structural analysis of devices and modeling of the - interaction between the device and cardiovascular anatomy. This paper will - provide an overview of computer modeling of the aortic root and describe FEA - approaches that could be applied to TAVI and have an impact on clinical practice - and device design. -FAU - Schoenhagen, Paul -AU - Schoenhagen P -AD - Imaging Institute and Heart & Vascular Institute, The Cleveland Clinic, Desk J-1 - 4, 9500 Euclid Avenue, Cleveland, OH 44195, USA. schoenp1@ccf.org -FAU - Hill, Alexander -AU - Hill A -FAU - Kelley, Tim -AU - Kelley T -FAU - Popovic, Zoran -AU - Popovic Z -FAU - Halliburton, Sandra S -AU - Halliburton SS -LA - eng -PT - Journal Article -PT - Review -DEP - 20110412 -PL - United States -TA - J Cardiovasc Transl Res -JT - Journal of cardiovascular translational research -JID - 101468585 -SB - IM -MH - Animals -MH - Aortic Valve/*diagnostic imaging -MH - Aortic Valve Stenosis/*diagnostic imaging/therapy -MH - Cardiac Catheterization/*instrumentation -MH - Computer Simulation -MH - Computer-Aided Design -MH - Finite Element Analysis -MH - *Heart Valve Prosthesis -MH - Heart Valve Prosthesis Implantation/*instrumentation/methods -MH - Humans -MH - *Imaging, Three-Dimensional -MH - Models, Cardiovascular -MH - Prosthesis Design -MH - *Radiographic Image Interpretation, Computer-Assisted -MH - *Tomography, X-Ray Computed -MH - Translational Research, Biomedical -EDAT- 2011/04/13 06:00 -MHDA- 2011/11/15 06:00 -CRDT- 2011/04/13 06:00 -PHST- 2011/02/10 00:00 [received] -PHST- 2011/03/30 00:00 [accepted] -PHST- 2011/04/13 06:00 [entrez] -PHST- 2011/04/13 06:00 [pubmed] -PHST- 2011/11/15 06:00 [medline] -AID - 10.1007/s12265-011-9277-z [doi] -PST - ppublish -SO - J Cardiovasc Transl Res. 2011 Aug;4(4):459-69. doi: 10.1007/s12265-011-9277-z. - Epub 2011 Apr 12. - -PMID- 23539920 -OWN - NLM -STAT- MEDLINE -DCOM- 20130912 -LR - 20190918 -IS - 0370-8179 (Print) -IS - 0370-8179 (Linking) -VI - 141 -IP - 1-2 -DP - 2013 Jan-Feb -TI - [Modern statin therapy in clinical practice: the lower the better]. -PG - 104-8 -AB - Lipid and lipoprotein disorders are well known risk factors for atherosclerosis - and its complications. The level of atherogenic LDL-cholesterol (LDL-C) is - directly related to an increased risk of occurrence and progression of ischemic - heart disease. Epidemiological and clinical studies have shown that the use of - statin therapy to decrease LDL-C can significantly reduce the incidence of - mortality, major coronary events and the need for revascularization procedures in - the different groups of patients. The findings of a large meta-analysis conducted - by the Cholesterol Treatment Trialists' (CTT) collaborators showed that every 1.0 - mmol/l reduction of atherogenic LDL-C is associated with a 22% reduction in - cardiovascular diseases mortality and morbidity. However, despite the impressive - results of the benefits of statin therapy, the EUROASPIRE study showed that about - 50% of patients with ischemic heart disease did not achieve target LDL-C levels. - According to the new ESC/EAS Guidelines for the Management of Dyslipidaemias in - patients with a very high cardiovascular risk, treatment goal should be to - decrease LDL-C below 1.8 mmol/l or > or = 50% of initial values. In the majority - of patients that can be achieved by statin therapy. For this reason an adequate - choice of statins is of crucial importance, whereby the needed reduction in - atherogenic LDL-C, after the identification of its target level based on the - assessment of total cardiovascular risk, can be achieved. -LA - srp -PT - English Abstract -PT - Journal Article -PT - Review -PL - Serbia -TA - Srp Arh Celok Lek -JT - Srpski arhiv za celokupno lekarstvo -JID - 0027440 -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Cholesterol, LDL/*blood -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage -MH - Myocardial Ischemia/blood/*prevention & control -EDAT- 2013/04/02 06:00 -MHDA- 2013/09/13 06:00 -CRDT- 2013/04/02 06:00 -PHST- 2013/04/02 06:00 [entrez] -PHST- 2013/04/02 06:00 [pubmed] -PHST- 2013/09/13 06:00 [medline] -AID - 10.2298/sarh1302104s [doi] -PST - ppublish -SO - Srp Arh Celok Lek. 2013 Jan-Feb;141(1-2):104-8. doi: 10.2298/sarh1302104s. - -PMID- 25696572 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20201001 -IS - 1568-5888 (Print) -IS - 1568-5888 (Linking) -VI - 14 -IP - 11 -DP - 2006 Nov -TI - The left bundle branch block revised with novel imaging modalities. -PG - 372-380 -AB - Left bundle branch block (LBBB) is related to abnormal cardiac conduction and - mechanical asynchrony and is associated with hypertension and coronary artery - disease. Improved evaluation of left ventricular (LV) mechanical asynchrony is - needed, because of the increasing number of patients with LBBB and heart failure. - In this paper, we describe tissue Doppler imaging (TDI), strain (rate) imaging - and tissue tracking in LBBB patients. A variety of patterns of mechanical - activation can be observed in LBBB patients. A recent development, referred to as - tissue synchronisation imaging, colour codes TDI time-to-peak systolic velocities - of segments and displays mechanical asynchrony. Furthermore, real-time 3D - echocardiography provides new regional information about mechanical asynchrony. - Contained in an LV model and projected on a bull's eye plot, this modality helps - to display the spatial distribution of mechanical asynchrony. Finally, segmental - time-to-peak circumferential strain curves, produced by cardiac magnetic - resonance imaging, provide additional quantification of LV mechanical asynchrony. - Effects of LBBB on regional and global cardiac function are impressive, - myocardial involvement seems to play a role and with the help of these novel - imaging modalities, new insights continue to develop. -FAU - van Dijk, J -AU - van Dijk J -FAU - Mannaerts, H F J -AU - Mannaerts HF -FAU - Germans, T -AU - Germans T -FAU - Hauer, H A -AU - Hauer HA -FAU - Knaapen, P -AU - Knaapen P -FAU - Visser, C A -AU - Visser CA -FAU - Kamp, O -AU - Kamp O -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Neth Heart J -JT - Netherlands heart journal : monthly journal of the Netherlands Society of - Cardiology and the Netherlands Heart Foundation -JID - 101095458 -PMC - PMC2557301 -OTO - NOTNLM -OT - asynchrony -OT - imaging modalities -OT - left bundle branch block -EDAT- 2006/11/01 00:00 -MHDA- 2006/11/01 00:01 -PMCR- 2006/11/01 -CRDT- 2015/02/20 06:00 -PHST- 2015/02/20 06:00 [entrez] -PHST- 2006/11/01 00:00 [pubmed] -PHST- 2006/11/01 00:01 [medline] -PHST- 2006/11/01 00:00 [pmc-release] -PST - ppublish -SO - Neth Heart J. 2006 Nov;14(11):372-380. - -PMID- 16370923 -OWN - NLM -STAT- MEDLINE -DCOM- 20060628 -LR - 20190917 -IS - 1744-7666 (Electronic) -IS - 1465-6566 (Linking) -VI - 7 -IP - 1 -DP - 2006 Jan -TI - Perindopril. -PG - 63-71 -AB - Perindopril is a third-generation ACE inhibitor that is characterised as a small, - lipophilic molecule with a therapeutically active carboxyl side group. These and - other features combine to make this a unique member of a very well-established - class of drugs that have proven efficacy in a wide range of cardiovascular - diseases. The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) - demonstrated benefit in the secondary prevention of patients with stroke, whereas - the Perindopril and Remodelling in Elderly with Acute Myocardial Infarction - (PREAMI) trial supports extended routine use after myocardial infarction. The - most recent evidence from the European Trial on Reduction of Cardiac Events with - Perindopril in Stable Coronary Artery Disease (EUROPA) and the Anglo-Scandinavian - Cardiac Outcomes Trial (ASCOT) show that perindopril is able to improve the - prognosis of patients with a relatively low global cardiovascular risk, denoted - either by the presence of stable coronary artery disease or of essential - hypertension in conjunction with at least three other risk factors. The fact that - major relative risk reductions have been reported for these two studies is - matched by the significance of the findings to modern clinical practice. Both - studies were conducted in the context of advance concomitant care that is - typically better in clinical trials than in routine practice. In particular, the - benefits observed were seen to be of a similar magnitude, and also independent of - those resulting from statin therapy. Of particular interest is the likely - complimentary action of these treatment strategies with regard to the - stabilisation of atheromatous plaques. Perindopril is a well-established drug, - the full value of which is only now becoming fully apparent. -FAU - Alfakih, K -AU - Alfakih K -AD - BHF Heart Research Centre, G Floor, Jubilee Wing, The Leeds General Infirmary, - Leeds, LS1 3EX, UK. -FAU - Hall, A S -AU - Hall AS -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Opin Pharmacother -JT - Expert opinion on pharmacotherapy -JID - 100897346 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Antihypertensive Agents) -RN - Y5GMK36KGY (Perindopril) -SB - IM -MH - Angiotensin-Converting Enzyme Inhibitors/chemistry/pharmacokinetics/therapeutic - use -MH - Animals -MH - Antihypertensive Agents/chemistry/pharmacokinetics/therapeutic use -MH - Cardiovascular Diseases/drug therapy/metabolism -MH - Humans -MH - Perindopril/chemistry/pharmacokinetics/*therapeutic use -RF - 33 -EDAT- 2005/12/24 09:00 -MHDA- 2006/06/29 09:00 -CRDT- 2005/12/24 09:00 -PHST- 2005/12/24 09:00 [pubmed] -PHST- 2006/06/29 09:00 [medline] -PHST- 2005/12/24 09:00 [entrez] -AID - 10.1517/14656566.7.1.63 [doi] -PST - ppublish -SO - Expert Opin Pharmacother. 2006 Jan;7(1):63-71. doi: 10.1517/14656566.7.1.63. - -PMID- 23587757 -OWN - NLM -STAT- MEDLINE -DCOM- 20140124 -LR - 20130506 -IS - 1531-7072 (Electronic) -IS - 1070-5295 (Linking) -VI - 19 -IP - 3 -DP - 2013 Jun -TI - Extracorporeal life support. -PG - 202-7 -LID - 10.1097/MCC.0b013e32836092a1 [doi] -AB - PURPOSE OF REVIEW: Refractory cardiac arrest still has a grave prognosis under - conventional cardiopulmonary resuscitation (CPR). We present the recent studies - in extracorporeal CPR (ECPR) for the treatment of refractory cardiac arrest. - RECENT FINDINGS: Apart from the studies of ECPR in pediatric in-hospital cardiac - arrest (IHCA), there was an increasing number of studies of this therapy in adult - IHCA and out-of-hospital cardiac arrest (OHCA). The indications for ECPR varied - across studies. In most cases ECPR was deployed on patients with reversible - cardiac diseases or other cardiac diseases such as congenital heart disease, - postcardiotomy arrest or acute myocardial infarction. Higher lactate values, - longer CPR duration and postresuscitation renal failure were associated with - increasing mortality. Percutaneous coronary intervention and therapeutic - hypothermia were increasingly used along with ECPR. SUMMARY: In this review, - survival after ECPR was generally best after pediatric IHCA (38-57%), followed by - adult IHCA (34-46%) and then adult OHCA (4-36%). Most studies reported that - longer conventional CPR duration was associated with mortality after ECPR; - however, there was no consensus on the optimal conventional CPR duration before - ECPR initiation. Future studies might focus on the indications for ECPR, which - should maximize the survival potential after ECPR while reducing the overuse of - this resource-intensive facility. -FAU - Wang, Chih-Hung -AU - Wang CH -AD - Department of Emergency Medicine, National Taiwan University Hospital, Taipei, - Taiwan. -FAU - Chen, Yih-Sharng -AU - Chen YS -FAU - Ma, Matthew Huei-Ming -AU - Ma MH -LA - eng -PT - Journal Article -PT - Multicenter Study -PT - Review -PL - United States -TA - Curr Opin Crit Care -JT - Current opinion in critical care -JID - 9504454 -SB - IM -MH - Adolescent -MH - Adult -MH - Advanced Cardiac Life Support/*methods -MH - Aged -MH - Child -MH - Child, Preschool -MH - Cohort Studies -MH - *Extracorporeal Membrane Oxygenation -MH - Heart Arrest/*therapy -MH - Humans -MH - Infant -MH - Infant, Newborn -MH - Middle Aged -MH - Survival Rate -MH - Young Adult -EDAT- 2013/04/17 06:00 -MHDA- 2014/01/25 06:00 -CRDT- 2013/04/17 06:00 -PHST- 2013/04/17 06:00 [entrez] -PHST- 2013/04/17 06:00 [pubmed] -PHST- 2014/01/25 06:00 [medline] -AID - 10.1097/MCC.0b013e32836092a1 [doi] -PST - ppublish -SO - Curr Opin Crit Care. 2013 Jun;19(3):202-7. doi: 10.1097/MCC.0b013e32836092a1. - -PMID- 17010820 -OWN - NLM -STAT- MEDLINE -DCOM- 20061012 -LR - 20220318 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 48 -IP - 7 -DP - 2006 Oct 3 -TI - Influenza vaccination as secondary prevention for cardiovascular disease: a - science advisory from the American Heart Association/American College of - Cardiology. -PG - 1498-502 -AB - Evidence from cohort studies and a randomized clinical trial indicates that - annual vaccination against seasonal influenza prevents cardiovascular morbidity - and all-cause mortality in patients with cardiovascular conditions. The American - Heart Association and American College of Cardiology recommend influenza - immunization with inactivated vaccine (administered intramuscularly) as part of - comprehensive secondary prevention in persons with coronary and other - atherosclerotic vascular disease (Class I, Level B). Immunization with live, - attenuated vaccine (administered intranasally) is not currently recommended - [corrected] for persons with cardiovascular conditions. It is important to note - that influenza vaccination coverage levels overall and in this population remain - well below national goals and are marked by disparities across different age and - ethnic groups. One of the barriers to vaccination for patients with - cardiovascular disease is that cardiology practices frequently do not stock and - administer influenza vaccine. Healthcare providers who treat individuals with - cardiovascular disease can help improve influenza vaccination coverage rates by - providing and strongly recommending vaccination to their patients before and - throughout the influenza season. -FAU - Davis, Matthew M -AU - Davis MM -FAU - Taubert, Kathryn -AU - Taubert K -FAU - Benin, Andrea L -AU - Benin AL -FAU - Brown, David W -AU - Brown DW -FAU - Mensah, George A -AU - Mensah GA -FAU - Baddour, Larry M -AU - Baddour LM -FAU - Dunbar, Sandra -AU - Dunbar S -FAU - Krumholz, Harlan M -AU - Krumholz HM -CN - American Heart Association -CN - American College of Cardiology -CN - American Association of Cardiovascular and Pulmonary Rehabilitation -CN - American Association of Critical Care Nurses -CN - American Association of Heart Failure Nurses -CN - American Diabetes Association -CN - Association of Black Cardiologists, Inc -CN - Heart Failure Society of America -CN - Preventive Cardiovascular Nurses Association -CN - American Academy of Nurse Practitioners -CN - Centers for Disease Control and Prevention and the Advisory Committee on - Immunization -LA - eng -PT - Journal Article -PT - Practice Guideline -PT - Review -DEP - 20060915 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Influenza Vaccines) -RN - 0 (Vaccines, Attenuated) -RN - 0 (Vaccines, Inactivated) -SB - IM -EIN - J Am Coll Cardiol. 2006 Dec 19;48(12):2610 -MH - Adult -MH - Age Factors -MH - Aged -MH - Cardiology -MH - Cardiovascular Diseases/*complications -MH - Contraindications -MH - Ethnicity -MH - Humans -MH - Immunization Schedule -MH - Influenza Vaccines/supply & distribution/*therapeutic use -MH - Influenza, Human/mortality/*prevention & control -MH - Middle Aged -MH - Risk Factors -MH - Vaccination/*statistics & numerical data -MH - Vaccines, Attenuated/therapeutic use -MH - Vaccines, Inactivated/therapeutic use -RF - 33 -EDAT- 2006/10/03 09:00 -MHDA- 2006/10/13 09:00 -CRDT- 2006/10/03 09:00 -PHST- 2006/10/03 09:00 [pubmed] -PHST- 2006/10/13 09:00 [medline] -PHST- 2006/10/03 09:00 [entrez] -AID - S0735-1097(06)02220-0 [pii] -AID - 10.1016/j.jacc.2006.09.004 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2006 Oct 3;48(7):1498-502. doi: 10.1016/j.jacc.2006.09.004. - Epub 2006 Sep 15. - -PMID- 22300387 -OWN - NLM -STAT- MEDLINE -DCOM- 20120912 -LR - 20191112 -VI - 7 -IP - 1 -DP - 2012 Apr -TI - A(3) adenosine receptor: a plausible therapeutic target for cardio-protection in - diabetes. -PG - 59-70 -AB - Diabetes mellitus categorized as type I and II, is a disease of pancreatic - insulin, affecting blood glucose level in the body. Recent evidence suggests that - cardiac diseases such as hypertension, coronary artery disease, congestive heart - failure, and diabetic cardiomyopathy are associated with diabetes and - hyperglycemia. The adenosine receptors (AR) have been reported to play an - important role in the regulation of these diseases. Four adenosine receptors have - been cloned and characterized from several different mammalian species. The - receptors are named adenosine A(1), A(2A), A(2B), and A(3). The A(2A) and A(2B) - receptors preferably interact with members of the Gs family of G proteins and the - A(1) and A(3) receptors with Gi/o proteins. The ubiquitous levels of adenosine - are found in each cell in normal conditions but in disease conditions its level - has been shown to increase and activate G-protein mediated signaling pathway - leading to artery constriction in cardiovascular diseases and diabetes. Various - studies have demonstrated that A(3)AR is a potent cardioprotectant during - myocardial ischemeia/ischemic reperfusion. Role of A(3)AR receptor as a possible - cardioprotectant in diabetes is under investigation and studies have verified the - involvement of cyclooxygenases (COXs) and NADPH oxidase pathways. This review - summarizes the possible role of A(3)AR in cardiovascular disease and discusses - advancement in the development of therapeutic agents targeting cardioprotection - with discussion on recent patents on A(3) agonists that are being utilized in the - clinical setting. We anticipate that detailed pharmacological studies of - adenosine A(3) receptors could help in understanding the link between - cardiovascular disease and diabetes and this can be utilized to develop newer - therapies that selectively target A(3) receptor to overcome cardiac challenges. -FAU - Nishat, Shamama -AU - Nishat S -AD - Dept. of Biosciences, Jamia Millia Islamia, New Delhi-110025, India. -FAU - Shabir, Hiba -AU - Shabir H -FAU - Azmi, Asfar S -AU - Azmi AS -FAU - Ansari, Habib R -AU - Ansari HR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Recent Pat Cardiovasc Drug Discov -JT - Recent patents on cardiovascular drug discovery -JID - 101263805 -RN - 0 (Adenosine A3 Receptor Agonists) -RN - 0 (Adenosine A3 Receptor Antagonists) -RN - 0 (Cardiotonic Agents) -RN - 0 (Receptor, Adenosine A3) -SB - IM -MH - Adenosine A3 Receptor Agonists/pharmacology/therapeutic use -MH - Adenosine A3 Receptor Antagonists/pharmacology/therapeutic use -MH - Animals -MH - Cardiotonic Agents/*pharmacology/*therapeutic use -MH - Diabetes Mellitus/*drug therapy/metabolism -MH - Heart Diseases/*drug therapy/*metabolism -MH - Humans -MH - Molecular Targeted Therapy -MH - Receptor, Adenosine A3/*metabolism -EDAT- 2012/02/04 06:00 -MHDA- 2012/09/13 06:00 -CRDT- 2012/02/04 06:00 -PHST- 2011/08/18 00:00 [received] -PHST- 2012/01/24 00:00 [revised] -PHST- 2012/01/24 00:00 [accepted] -PHST- 2012/02/04 06:00 [entrez] -PHST- 2012/02/04 06:00 [pubmed] -PHST- 2012/09/13 06:00 [medline] -AID - PRC-EPUB-20120202-001 [pii] -AID - 10.2174/157489012799362421 [doi] -PST - ppublish -SO - Recent Pat Cardiovasc Drug Discov. 2012 Apr;7(1):59-70. doi: - 10.2174/157489012799362421. - -PMID- 17562779 -OWN - NLM -STAT- MEDLINE -DCOM- 20070727 -LR - 20071115 -IS - 1074-2484 (Print) -IS - 1074-2484 (Linking) -VI - 12 -IP - 2 -DP - 2007 Jun -TI - Therapeutic angiogenesis with bone marrow--derived stem cells. -PG - 89-97 -AB - Despite that advances in medical treatment and interventional procedures have - reduced the mortality rate in patients with coronary artery disease, the number - of patients with refractory myocardial ischemia and congestive heart failure is - rapidly increasing. Experimental studies have demonstrated that bone marrow (BM) - contains adult stem cells that can induce neovascularization and improve heart - function in ischemic myocardium. Recent insights into the understanding of the - mechanisms involved in proliferation, recruitment, mobilization, and - incorporation of BM-derived stem cells into the myocardium and blood vessels have - prompted development of cellular transplantation therapy for heart diseases - refractory to conventional therapy. Initial preliminary clinical studies - indicated potential clinical benefit of BM therapy in patients with acute - myocardial infarction and chronic myocardial ischemia. Nevertheless, many - obstacles remain, such as long-term safety and optimal timing and treatment - strategies for BM cell therapy, and these issues need to be addressed in - rationally designed, randomized clinical trials. -FAU - Tse, Hung-Fat -AU - Tse HF -AD - Cardiology Division, Department of Medicine, Queen Mary Hospital, The University - of Hong Kong, Hong Kong, China. hftse@ hkucc.hku.hk -FAU - Lau, Chu-Pak -AU - Lau CP -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Cardiovasc Pharmacol Ther -JT - Journal of cardiovascular pharmacology and therapeutics -JID - 9602617 -RN - 0 (Colony-Stimulating Factors) -SB - IM -MH - Bone Marrow Cells -MH - Clinical Trials as Topic -MH - Colony-Stimulating Factors/therapeutic use -MH - Humans -MH - Myocardial Infarction/*therapy -MH - Myocardial Ischemia/*therapy -MH - Myocardium/metabolism/pathology -MH - *Neovascularization, Physiologic -MH - *Stem Cell Transplantation -MH - Stem Cells -RF - 57 -EDAT- 2007/06/15 09:00 -MHDA- 2007/07/28 09:00 -CRDT- 2007/06/15 09:00 -PHST- 2007/06/15 09:00 [pubmed] -PHST- 2007/07/28 09:00 [medline] -PHST- 2007/06/15 09:00 [entrez] -AID - 12/2/89 [pii] -AID - 10.1177/1074248407303139 [doi] -PST - ppublish -SO - J Cardiovasc Pharmacol Ther. 2007 Jun;12(2):89-97. doi: 10.1177/1074248407303139. - -PMID- 22489719 -OWN - NLM -STAT- MEDLINE -DCOM- 20120911 -LR - 20190823 -IS - 1875-533X (Electronic) -IS - 0929-8673 (Linking) -VI - 19 -IP - 16 -DP - 2012 -TI - Biomarkers as a guide of medical treatment in cardiovascular diseases. -PG - 2485-96 -AB - There is increasing interest in utilizing novel markers of cardiovascular disease - risk and consequently, there is a need to assess the value of their use. In this - paper, we will review the role of biomarkers in acute coronary syndromes, heart - failure and risk stratification for cardiovascular events as guide for treatment - scribing. In particular, high sensitivity assays for troponin evaluation detect - with greater precision patients with elevated troponin. Therefore, direct and - appropriate management is succeeded in these patients with reduction of - complications due to earlier treatment, as well. Regarding heart failure, - randomized trials that have evaluated biomarker guided treatment approach have - not succeeded in establishing specific results for natriuretic peptides (BNP, - NT-proBNP) use in terms of therapy guidance. Apart from them, a variety of novel - or already used biomarkers, have been tested by small trials for heart failure - management, without however, managing to dominate in every day care. Finally, as - far as risk stratification for cardiovascular events is concerned, hsCRP has - proved to be a strong but doubted biomarker. Therefore, lifestyle and behavioral - modification remain the cornerstone of primary prevention. -FAU - Vavuranakis, M -AU - Vavuranakis M -AD - 1st Dpt. of Cardiology, Hippocration Hospital, Medical School, National & - Kapodistrian University of Athens, Greece. vavouran@otenet.gr -FAU - Kariori, M G -AU - Kariori MG -FAU - Kalogeras, K I -AU - Kalogeras KI -FAU - Vrachatis, D A -AU - Vrachatis DA -FAU - Moldovan, C -AU - Moldovan C -FAU - Tousoulis, D -AU - Tousoulis D -FAU - Stefanadis, C -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Biomarkers) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Natriuretic Peptides) -RN - 0 (Troponin) -RN - 9007-41-4 (C-Reactive Protein) -SB - IM -MH - Animals -MH - Biomarkers/*metabolism -MH - C-Reactive Protein/metabolism -MH - Cardiovascular Diseases/diagnosis/drug therapy/*metabolism -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Natriuretic Peptides/metabolism -MH - Troponin/metabolism -EDAT- 2012/04/12 06:00 -MHDA- 2012/09/12 06:00 -CRDT- 2012/04/12 06:00 -PHST- 2011/11/18 00:00 [received] -PHST- 2012/01/05 00:00 [revised] -PHST- 2012/01/17 00:00 [accepted] -PHST- 2012/04/12 06:00 [entrez] -PHST- 2012/04/12 06:00 [pubmed] -PHST- 2012/09/12 06:00 [medline] -AID - CDT-EPUB-20120205-006 [pii] -AID - 10.2174/092986712800492977 [doi] -PST - ppublish -SO - Curr Med Chem. 2012;19(16):2485-96. doi: 10.2174/092986712800492977. - -PMID- 20180026 -OWN - NLM -STAT- MEDLINE -DCOM- 20100614 -LR - 20250529 -IS - 1573-2606 (Electronic) -IS - 1389-9155 (Print) -IS - 1389-9155 (Linking) -VI - 11 -IP - 1 -DP - 2010 Mar -TI - Diabetic cardiomyopathy, causes and effects. -PG - 31-9 -LID - 10.1007/s11154-010-9131-7 [doi] -AB - Diabetes is associated with increased incidence of heart failure even after - controlling for coronary artery disease and hypertension. Thus, as diabetic - cardiomyopathy has become an increasingly recognized entity among clinicians, a - better understanding of its pathophysiology is necessary for early diagnosis and - the development of treatment strategies for diabetes-associated cardiovascular - dysfunction. We will review recent basic and clinical research into the - manifestations and the pathophysiological mechanisms of diabetic cardiomyopathy. - The discussion will be focused on the structural, functional and metabolic - changes that occur in the myocardium in diabetes and how these changes may - contribute to the development of diabetic cardiomyopathy in affected humans and - relevant animal models. -FAU - Boudina, Sihem -AU - Boudina S -AD - Division of Endocrinology Metabolism and Diabetes, Program in Molecular Medicine, - University of Utah School of Medicine, 15 North 2030 East, Bldg. 533 Room 3110B, - Salt Lake City, UT 84112, USA. -FAU - Abel, Evan Dale -AU - Abel ED -LA - eng -GR - P30 HL101310/HL/NHLBI NIH HHS/United States -GR - R01 DK092065/DK/NIDDK NIH HHS/United States -GR - U01 HL087947/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Germany -TA - Rev Endocr Metab Disord -JT - Reviews in endocrine & metabolic disorders -JID - 100940588 -RN - 0 (Fatty Acids) -SB - IM -MH - Cardiomyopathies/*etiology -MH - *Diabetes Complications -MH - Fatty Acids/adverse effects -MH - Female -MH - Fibrosis -MH - Heart Failure, Diastolic/etiology -MH - Humans -MH - Hypertrophy, Left Ventricular/complications/etiology -MH - Male -MH - Mitochondria, Heart/physiology -MH - Myocardium/pathology -MH - Necrosis -MH - Obesity/complications -MH - Oxidative Stress -PMC - PMC2914514 -MID - NIHMS222484 -EDAT- 2010/02/25 06:00 -MHDA- 2010/06/15 06:00 -PMCR- 2010/09/01 -CRDT- 2010/02/25 06:00 -PHST- 2010/02/25 06:00 [entrez] -PHST- 2010/02/25 06:00 [pubmed] -PHST- 2010/06/15 06:00 [medline] -PHST- 2010/09/01 00:00 [pmc-release] -AID - 10.1007/s11154-010-9131-7 [doi] -PST - ppublish -SO - Rev Endocr Metab Disord. 2010 Mar;11(1):31-9. doi: 10.1007/s11154-010-9131-7. - -PMID- 20031381 -OWN - NLM -STAT- MEDLINE -DCOM- 20100528 -LR - 20131121 -IS - 1590-3729 (Electronic) -IS - 0939-4753 (Linking) -VI - 20 -IP - 3 -DP - 2010 Mar -TI - Metabolic toxicity of the heart: insights from molecular imaging. -PG - 147-56 -LID - 10.1016/j.numecd.2009.08.011 [doi] -AB - There is convincing evidence that alterations in myocardial substrate use play an - important role in the normal and diseased heart. In this review, insights gained - by using quantitative molecular imaging by positron emission tomography and - magnetic resonance spectroscopy in the study of human myocardial metabolism will - be discussed, and attention will be paid to the effects of nutrition, gender, - aging, obesity, diabetes, cardiac hypertrophy, ischemia, and heart failure. The - heart is an omnivore organ, relying on metabolic flexibility, which is - compromised by the occurrence of defects in coronary flow reserve, - insulin-mediated glucose disposal, and metabolic-mechanical coupling. Obesity, - diabetes, and ischemic cardiomyopathy appear as states of high uptake and - oxidation of fatty acids, that compromise the ability to utilize glucose under - stimulated conditions, and lead to misuse of energy and oxygen, disturbing - mechanical efficiency. Idiopathic heart failure is a complex disease frequently - coexisting with diabetes, insulin resistance and hypertension, in which the end - stage of metabolic toxicity manifests as severe mitochondrial disturbance, - inability to utilize fatty acids, and ATP depletion. The current literature - provides evidence that the primary events in the metabolic cascade outlined may - originate in extra-cardiac organs, since fatty acid, glucose levels, and insulin - action are mostly controlled by adipose tissue, skeletal muscle and liver, and - that a broader vision of organ cross-talk may further our understanding of the - primary and the adaptive events involved in metabolic heart toxicity. -CI - (c) 2009 Elsevier B.V. All rights reserved. -FAU - Iozzo, P -AU - Iozzo P -AD - Institute of Clinical Physiology, National Research Council (CNR), Via Moruzzi 1, - 56124 Pisa, Italy. patricia.iozzo@ifc.cnr.it -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -DEP - 20091222 -PL - Netherlands -TA - Nutr Metab Cardiovasc Dis -JT - Nutrition, metabolism, and cardiovascular diseases : NMCD -JID - 9111474 -RN - 0 (Fatty Acids) -RN - 020IUV4N33 (Phosphocreatine) -RN - 8L70Q75FXE (Adenosine Triphosphate) -RN - IY9XDZ35W2 (Glucose) -SB - IM -MH - Adenosine Triphosphate/analysis -MH - Aging/metabolism -MH - Diabetes Mellitus/metabolism -MH - Energy Metabolism -MH - Fatty Acids/metabolism -MH - Female -MH - Glucose/metabolism -MH - Heart Diseases/*metabolism -MH - Humans -MH - *Magnetic Resonance Spectroscopy -MH - Male -MH - Middle Aged -MH - Myocardial Ischemia/metabolism -MH - Myocardium/*metabolism -MH - Obesity/metabolism -MH - Oxygen Consumption -MH - Phosphocreatine/analysis -MH - *Positron-Emission Tomography -MH - Sex Factors -RF - 96 -EDAT- 2009/12/25 06:00 -MHDA- 2010/05/29 06:00 -CRDT- 2009/12/25 06:00 -PHST- 2009/03/05 00:00 [received] -PHST- 2009/07/29 00:00 [revised] -PHST- 2009/08/21 00:00 [accepted] -PHST- 2009/12/25 06:00 [entrez] -PHST- 2009/12/25 06:00 [pubmed] -PHST- 2010/05/29 06:00 [medline] -AID - S0939-4753(09)00210-5 [pii] -AID - 10.1016/j.numecd.2009.08.011 [doi] -PST - ppublish -SO - Nutr Metab Cardiovasc Dis. 2010 Mar;20(3):147-56. doi: - 10.1016/j.numecd.2009.08.011. Epub 2009 Dec 22. - -PMID- 18377766 -OWN - NLM -STAT- MEDLINE -DCOM- 20080522 -LR - 20191110 -IS - 1488-2353 (Electronic) -IS - 0147-958X (Linking) -VI - 31 -IP - 2 -DP - 2008 -TI - Aquatic therapies in patients with compromised left ventricular function and - heart failure. -PG - E90-7 -AB - With water immersion, gravity is partly eliminated, and the water exerts a - pressure on the body surface. Consequently there is a blood volume shift from the - periphery to the central circulation, resulting in marked volume loading of the - thorax and heart. This paper presents a selection of published literature on - water immersion, balneotherapy, aqua exercises, and swimming, in patients with - left ventricular dysfunction (LVD) and/or stable chronic heart failure (CHF). - Based on exploratory studies, central hemodynamic and neurohumoral responses of - aquatic therapies will be illustrated. Major findings are: 1. In LVD and CHF, a - positive effect of therapeutic warm-water tub bathing has been observed, which is - assumed to be from afterload reduction due to peripheral vasodilatation caused by - the warm water. 2. In coronary patients with LVD, at low-level water cycling the - heart is working more efficiently than at lowlevel cycling outside of water. 3. - In patients with previous extensive myocardial infarction, upright immersion to - the neck resulted in temporary pathological increases in mean pulmonary artery - pressure (mPAP) and mean pulmonary capillary pressures (mPCP). 4. Additionally, - during slow swimming (20-25m/min) the mPAP and/or PCP were higher than during - supine cycling outside water at a 100W load. 5. In CHF patients, neck- deep - immersion resulted in a decrease or no change in stroke volume. 6. Although - patients are hemodynamically compromised, they usually maintain a feeling of - well-being during aquatic therapy. Based on these findings, clinical indications - for aquatic therapies are proposed and ideas are presented to provoke further - research. -FAU - Meyer, Katharina -AU - Meyer K -AD - University of Bern & Swiss Health Observatory, Switzerland. - meyer.katharina@bluewin.ch -FAU - Leblanc, Marie-Claude -AU - Leblanc MC -LA - eng -PT - Journal Article -PT - Review -PL - Canada -TA - Clin Invest Med -JT - Clinical and investigative medicine. Medecine clinique et experimentale -JID - 7804071 -SB - IM -MH - Chronic Disease -MH - Echocardiography/methods -MH - Exercise -MH - Exercise Therapy/methods -MH - Heart Failure/*rehabilitation/*therapy -MH - Hemodynamics -MH - Humans -MH - Immersion -MH - Swimming -MH - Ventricular Dysfunction, Left/*rehabilitation/*therapy -MH - Ventricular Function, Left -RF - 30 -EDAT- 2008/04/02 09:00 -MHDA- 2008/05/23 09:00 -CRDT- 2008/04/02 09:00 -PHST- 2008/04/02 09:00 [pubmed] -PHST- 2008/05/23 09:00 [medline] -PHST- 2008/04/02 09:00 [entrez] -AID - 10.25011/cim.v31i2.3369 [doi] -PST - ppublish -SO - Clin Invest Med. 2008;31(2):E90-7. doi: 10.25011/cim.v31i2.3369. - -PMID- 19454044 -OWN - NLM -STAT- MEDLINE -DCOM- 20160422 -LR - 20250623 -IS - 1752-8526 (Electronic) -VI - 2007 -DP - 2007 Jan 1 -TI - Heart failure. -LID - 0204 [pii] -AB - INTRODUCTION: Heart failure occurs in 3-4% of adults aged over 65 years, usually - as a consequence of coronary artery disease or hypertension, and causes - breathlessness, effort intolerance, fluid retention, and increased mortality. The - 5-year mortality in people with systolic heart failure ranges from 25-75%, often - due to sudden death following ventricular arrhythmia. Risks of cardiovascular - events are increased in people with LVSD or heart failure. METHODS AND OUTCOMES: - We conducted a systematic review and aimed to answer the following clinical - questions: What are the effects of non-drug treatments, and of drug and invasive - treatments for heart failure? What are the effects of angiotensin-converting - enzyme inhibitors in people at high risk of heart failure? What are the effects - of treatments for diastolic heart failure? We searched: Medline, Embase, The - Cochrane Library and other important databases up to January 2007 (Clinical - Evidence reviews are updated periodically, please check our website for the most - up-to-date version of this review). We included harms alerts from relevant - organisations such as the US Food and Drug Administration (FDA) and the UK - Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found 72 - systematic reviews, RCTs, or observational studies that met our inclusion - criteria. We performed a GRADE evaluation of the quality of evidence for - interventions. CONCLUSIONS: In this systematic review we present information - relating to the effectiveness and safety of the following interventions: - amiodarone, angiotensin-converting enzyme inhibitors, angiotensin II receptor - blockers, anticoagulation, antiplatelet agents, beta-blockers, calcium channel - blockers, cardiac resynchronisation therapy, digoxin (in people already receiving - diuretics and angiotensin-converting enzyme inhibitors), eplerenone, exercise, - implantable cardiac defibrillators, multidisciplinary interventions, - non-amiodarone antiarrhythmic drugs, positive inotropes (other than digoxin), and - spironolactone. -FAU - McKelvie, Robert Samuel -AU - McKelvie RS -AD - McMaster University, Hamilton, ON, Canada. -LA - eng -PT - Journal Article -PT - Systematic Review -DEP - 20070101 -PL - England -TA - BMJ Clin Evid -JT - BMJ clinical evidence -JID - 101294314 -SB - IM -MH - *Heart Failure -MH - United States -EDAT- 2007/01/01 00:00 -MHDA- 2016/04/23 06:00 -CRDT- 2009/05/21 09:00 -PHST- 2009/05/21 09:00 [entrez] -PHST- 2007/01/01 00:00 [pubmed] -PHST- 2016/04/23 06:00 [medline] -AID - 0204 [pii] -PST - epublish -SO - BMJ Clin Evid. 2007 Jan 1;2007:0204. - -PMID- 24062561 -OWN - NLM -STAT- MEDLINE -DCOM- 20131114 -LR - 20250529 -IS - 1527-1315 (Electronic) -IS - 0033-8419 (Linking) -VI - 269 -IP - 1 -DP - 2013 Oct -TI - MR imaging of the arterial vessel wall: molecular imaging from bench to bedside. -PG - 34-51 -LID - 10.1148/radiol.13102336 [doi] -AB - Cardiovascular diseases remain the leading cause of morbidity and mortality in - the Western world and developing countries. In clinical practice, in vivo - characterization of atherosclerotic lesions causing myocardial infarction, - ischemic stroke, and other complications remains challenging. Imaging methods, - limited to the assessment luminal stenosis, are the current reference standard - for the assessment of clinically significant coronary and carotid artery disease - and the guidance of treatment. These techniques do not allow distinction between - stable and potentially vulnerable atherosclerotic plaque. Magnetic resonance (MR) - imaging is a modality well suited for visualization and characterization of the - relatively thin arterial vessel wall, because it allows imaging with high spatial - resolution and excellent soft-tissue contrast. In clinical practice, - atherosclerotic plaque components of the carotid artery and aorta may be - differentiated and characterized by using unenhanced vessel wall MR imaging. - Additional information can be gained by using clinically approved nonspecific - contrast agents. With the advent of targeted MR contrast agents, which enhance - specific molecules or cells, pathologic processes can be visualized at a - molecular level with high spatial resolution. In this article, the - pathophysiologic changes of the arterial vessel wall underlying the development - of atherosclerosis will be first reviewed. Then basic principles and properties - of molecular MR imaging contrast agents will be introduced. Additionally, recent - advances in preclinical molecular vessel wall imaging will be reviewed. Finally, - the clinical feasibility of arterial vessel wall imaging at unenhanced and - contrast material-enhanced MR imaging of the aortic, carotid, and coronary vessel - wall will be discussed. -CI - © RSNA, 2013. -FAU - Makowski, Marcus R -AU - Makowski MR -AD - Division of Imaging Sciences, BHF Centre of Excellence, Wellcome Trust and EPSRC - Medical Engineering Center, and NIHR Biomedical Research Centre, King's College - London, 4th Floor, Lambeth Wing, St Thomas Hospital, London SE1 7EH, England. -FAU - Botnar, René M -AU - Botnar RM -LA - eng -GR - PG/10/44/28343/BHF_/British Heart Foundation/United Kingdom -GR - RG/12/1/29262/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Radiology -JT - Radiology -JID - 0401260 -SB - IM -MH - Atherosclerosis/*diagnosis -MH - Humans -MH - Magnetic Resonance Angiography/*methods -MH - Molecular Imaging/*methods -MH - Translational Research, Biomedical/*methods -EDAT- 2013/09/26 06:00 -MHDA- 2013/11/15 06:00 -CRDT- 2013/09/25 06:00 -PHST- 2013/09/25 06:00 [entrez] -PHST- 2013/09/26 06:00 [pubmed] -PHST- 2013/11/15 06:00 [medline] -AID - 269/1/34 [pii] -AID - 10.1148/radiol.13102336 [doi] -PST - ppublish -SO - Radiology. 2013 Oct;269(1):34-51. doi: 10.1148/radiol.13102336. - -PMID- 21125979 -OWN - NLM -STAT- MEDLINE -DCOM- 20110104 -LR - 20220330 -IS - 0001-5385 (Print) -IS - 0001-5385 (Linking) -VI - 65 -IP - 5 -DP - 2010 Oct -TI - Beta-blockers: focus on mechanism of action. Which beta-blocker, when and why? -PG - 565-70 -AB - Beta-blockers are a heterogeneous group of antihypertensive agents. What they - have in common is competitive antagonistic action on beta-adrenoreceptors (B1, B2 - and B3). They differ in their receptor selectivity, intrinsic sympathomimetic - activity (ISA), vasodilating properties and metabolism. Antihypertensive - mechanisms and effect differ according to receptor-specificity and ISA, where - differences in duration of action also have to be considered. An unfavourable - metabolic profile of beta-blockers was reported based on studies describing the - metabolic side effects of weakly-selective or non-selective agents. Newer - generation beta-blockers appear to have a metabolic neutral profile. In systolic - heart failure, three agents proved to improve survival up to 30%, mainly because - of B1-blocking and/or vasodilating properties. The position of beta-blockers in - treating diastolic heart failure remains uncertain. Beta-blocker therapy in - coronary artery disease also leads to uncontested survival benefit, the - cardioprotective mechanism largely due to rate reduction. This paper aims to - describe the basis of heterogeneity of the available agents and to translate this - into their applicability in different cardiovascular diseases, with focus on the - underlying physiopathological mechanisms. -FAU - Gorre, Frauke -AU - Gorre F -AD - Department of Cardiology, University Hospital Ghent, Belgium. - frauke.gorre@ugent.be -FAU - Vandekerckhove, Hans -AU - Vandekerckhove H -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Acta Cardiol -JT - Acta cardiologica -JID - 0370570 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Antihypertensive Agents) -RN - 0 (Blood Glucose) -RN - 0 (Receptors, Adrenergic, beta) -RN - 0 (Vasodilator Agents) -SB - IM -MH - Adrenergic beta-Antagonists/*pharmacology/therapeutic use -MH - Antihypertensive Agents/pharmacology/therapeutic use -MH - Blood Glucose/analysis -MH - Heart Failure/drug therapy/physiopathology -MH - Heart Rate/physiology -MH - Humans -MH - Receptors, Adrenergic, beta/drug effects -MH - Sympathetic Nervous System/physiopathology -MH - Vasodilator Agents/pharmacology/therapeutic use -EDAT- 2010/12/04 06:00 -MHDA- 2011/01/05 06:00 -CRDT- 2010/12/04 06:00 -PHST- 2010/12/04 06:00 [entrez] -PHST- 2010/12/04 06:00 [pubmed] -PHST- 2011/01/05 06:00 [medline] -AID - 10.1080/ac.65.5.2056244 [doi] -PST - ppublish -SO - Acta Cardiol. 2010 Oct;65(5):565-70. doi: 10.1080/ac.65.5.2056244. - -PMID- 23817188 -OWN - NLM -STAT- MEDLINE -DCOM- 20140318 -LR - 20240222 -IS - 1759-5010 (Electronic) -IS - 1759-5002 (Print) -IS - 1759-5002 (Linking) -VI - 10 -IP - 9 -DP - 2013 Sep -TI - Presentation, management, and outcomes of ischaemic heart disease in women. -PG - 508-18 -LID - 10.1038/nrcardio.2013.93 [doi] -AB - Scientific interest in ischaemic heart disease (IHD) in women has grown - considerably over the past 2 decades. A substantial amount of the literature on - this subject is centred on sex differences in clinical aspects of IHD. Many - reports have documented sex-related differences in presentation, risk profiles, - and outcomes among patients with IHD, particularly acute myocardial infarction. - Such differences have often been attributed to inequalities between men and women - in the referral and treatment of IHD, but data are insufficient to support this - assessment. The determinants of sex differences in presentation are unclear, and - few clues are available as to why young, premenopausal women paradoxically have a - greater incidence of adverse outcomes after acute myocardial infarction than men, - despite having less-severe coronary artery disease. Although differential - treatment on the basis of patient sex continues to be described, the extent to - which such inequalities persist and whether they reflect true disparity is - unclear. Additionally, much uncertainty surrounds possible sex-related - differences in response to cardiovascular therapies, partly because of a - persistent lack of female-specific data from cardiovascular clinical trials. In - this Review, we assess the evidence for sex-related differences in the clinical - presentation, treatment, and outcome of IHD, and identify gaps in the literature - that need to be addressed in future research efforts. -FAU - Vaccarino, Viola -AU - Vaccarino V -AD - Emory University Rollins School of Public Health and School of Medicine, USA. -FAU - Badimon, Lina -AU - Badimon L -FAU - Corti, Roberto -AU - Corti R -FAU - de Wit, Cor -AU - de Wit C -FAU - Dorobantu, Maria -AU - Dorobantu M -FAU - Manfrini, Olivia -AU - Manfrini O -FAU - Koller, Akos -AU - Koller A -FAU - Pries, Axel -AU - Pries A -FAU - Cenko, Edina -AU - Cenko E -FAU - Bugiardini, Raffaele -AU - Bugiardini R -LA - eng -GR - K24 HL077506/HL/NHLBI NIH HHS/United States -GR - K24HL077506/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130702 -PL - England -TA - Nat Rev Cardiol -JT - Nature reviews. Cardiology -JID - 101500075 -SB - IM -MH - Aged -MH - Female -MH - *Health Status Disparities -MH - Healthcare Disparities -MH - Humans -MH - Male -MH - Middle Aged -MH - Myocardial Ischemia/*diagnosis/epidemiology/*therapy -MH - Predictive Value of Tests -MH - Risk Factors -MH - Sex Factors -MH - Treatment Outcome -MH - *Women's Health -PMC - PMC10878732 -MID - NIHMS1965124 -COIS- Competing interests The authors declare no competing interests. -EDAT- 2013/07/03 06:00 -MHDA- 2014/03/19 06:00 -PMCR- 2024/02/20 -CRDT- 2013/07/03 06:00 -PHST- 2013/07/03 06:00 [entrez] -PHST- 2013/07/03 06:00 [pubmed] -PHST- 2014/03/19 06:00 [medline] -PHST- 2024/02/20 00:00 [pmc-release] -AID - nrcardio.2013.93 [pii] -AID - 10.1038/nrcardio.2013.93 [doi] -PST - ppublish -SO - Nat Rev Cardiol. 2013 Sep;10(9):508-18. doi: 10.1038/nrcardio.2013.93. Epub 2013 - Jul 2. - -PMID- 17333064 -OWN - NLM -STAT- MEDLINE -DCOM- 20070808 -LR - 20181113 -IS - 0033-832X (Print) -IS - 0033-832X (Linking) -VI - 47 -IP - 4 -DP - 2007 Apr -TI - [Cardiac MR imaging in arrhythmogenic heart diseases]. -PG - 325-32 -AB - INTRODUCTION: Cardiac arrhythmias are assessed with a combination of history, - clinical examination, electrocardiogram, Holter monitor, if necessary - supplemented by invasive cardiac electrophysiology. In ischemic heart disease - (IHD) coronary angiography is performed in addition. METHODS: Echocardiography is - usually the primary imaging modality. MRI is increasingly recognized as an - important investigation allowing more accurate cardiac morphological and - functional assessment. RESULTS: Approximately one-fifth of deaths in Western - countries are due to sudden cardiac death, 80% of which are caused by - arrhythmias. Typical causes range from diseases with high prevalence (IHD in men - 30%) to myocarditis (prevalence 1-9%) and rare cardiomyopathies (prevalence HCM - 0.2%, ARVC 0.02%, Brugada syndrome approx. 0.5%). The characteristic MRI features - of arrhythmogenic diseases and the new aspects of characteristic distribution of - late enhancement allow etiologic classification and differential diagnosis. - CONCLUSION: MRI represents an important tool for detection of the underlying - cause and for risk stratification in many diseases associated with arrhythmias. -FAU - Böhm, C K -AU - Böhm CK -AD - Institut für Klinische Radiologie, Universitätsklinikum Mannheim, - Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland. - christoph.boehm@rad.ma.uni-heidelberg.de -FAU - Papavassiliu, T -AU - Papavassiliu T -FAU - Dinter, D J -AU - Dinter DJ -FAU - Diehl, S J -AU - Diehl SJ -FAU - Borggrefe, M -AU - Borggrefe M -FAU - Neff, K W -AU - Neff KW -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Kardiale MRT in der Diagnostik arrhythmogener Herzerkrankungen. -PL - Germany -TA - Radiologe -JT - Der Radiologe -JID - 0401257 -SB - IM -MH - Arrhythmias, Cardiac/complications/*diagnosis -MH - Cardiomyopathies/*diagnosis/etiology -MH - Humans -MH - Image Enhancement/*methods -MH - Magnetic Resonance Imaging/*methods -MH - Practice Guidelines as Topic -MH - Practice Patterns, Physicians' -RF - 37 -EDAT- 2007/03/03 09:00 -MHDA- 2007/08/09 09:00 -CRDT- 2007/03/03 09:00 -PHST- 2007/03/03 09:00 [pubmed] -PHST- 2007/08/09 09:00 [medline] -PHST- 2007/03/03 09:00 [entrez] -AID - 10.1007/s00117-007-1487-7 [doi] -PST - ppublish -SO - Radiologe. 2007 Apr;47(4):325-32. doi: 10.1007/s00117-007-1487-7. - -PMID- 23867906 -OWN - NLM -STAT- MEDLINE -DCOM- 20140519 -LR - 20131015 -IS - 1879-016X (Electronic) -IS - 0163-7258 (Linking) -VI - 140 -IP - 3 -DP - 2013 Dec -TI - Mitochondrial inner membrane lipids and proteins as targets for decreasing - cardiac ischemia/reperfusion injury. -PG - 258-66 -LID - S0163-7258(13)00151-4 [pii] -LID - 10.1016/j.pharmthera.2013.07.005 [doi] -AB - A major manifestation of coronary artery disease is cardiac ischemia/reperfusion - injury, with the extent of injury directly relating to short- and long-term - prognosis. Emerging evidence suggests that mitochondrial dysfunction is centrally - involved in ischemia/reperfusion injury. In this review, we summarize the role of - mitochondria in the etiology of ischemia/reperfusion injury. We attempt to - highlight emerging areas for cardiac mitochondrial medicine and discuss recent - advances regarding the molecular composition of inner membrane channels. We - discuss interactions between lipids and proteins in the inner mitochondrial - membrane, and the ever-evolving nature of this relationship during - ischemia/reperfusion. Potentially novel treatments influencing the biophysical - properties of inner membrane lipids (such as cardiolipin) are presented. Finally, - we point to areas where future study is needed to expand and improve our - understanding of mitochondrial pathophysiology during cardiac - ischemia/reperfusion. -CI - © 2013. -FAU - Brown, David A -AU - Brown DA -AD - Department of Physiology, Brody School of Medicine, East Carolina University, - Greenville, NC, USA; East Carolina Diabetes and Obesity Institute, Brody School - of Medicine, East Carolina University, Greenville, NC, USA. Electronic address: - brownda@ecu.edu. -FAU - Sabbah, Hani N -AU - Sabbah HN -FAU - Shaikh, Saame Raza -AU - Shaikh SR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130715 -PL - England -TA - Pharmacol Ther -JT - Pharmacology & therapeutics -JID - 7905840 -RN - 0 (Membrane Lipids) -RN - 0 (Membrane Proteins) -SB - IM -MH - Animals -MH - Humans -MH - Membrane Lipids/*metabolism -MH - Membrane Proteins/*metabolism -MH - Mitochondria, Heart/drug effects/*metabolism -MH - Mitochondrial Membranes/drug effects/*metabolism -MH - Myocardial Reperfusion Injury/drug therapy/*metabolism -MH - Reperfusion Injury/drug therapy/metabolism -OTO - NOTNLM -OT - Cardiolipin -OT - Cardioprotection -OT - Heart -OT - Mitochondria -EDAT- 2013/07/23 06:00 -MHDA- 2014/05/20 06:00 -CRDT- 2013/07/23 06:00 -PHST- 2013/07/08 00:00 [received] -PHST- 2013/07/09 00:00 [accepted] -PHST- 2013/07/23 06:00 [entrez] -PHST- 2013/07/23 06:00 [pubmed] -PHST- 2014/05/20 06:00 [medline] -AID - S0163-7258(13)00151-4 [pii] -AID - 10.1016/j.pharmthera.2013.07.005 [doi] -PST - ppublish -SO - Pharmacol Ther. 2013 Dec;140(3):258-66. doi: 10.1016/j.pharmthera.2013.07.005. - Epub 2013 Jul 15. - -PMID- 19463525 -OWN - NLM -STAT- MEDLINE -DCOM- 20090618 -LR - 20220330 -IS - 1879-1913 (Electronic) -IS - 0002-9149 (Linking) -VI - 103 -IP - 11 -DP - 2009 Jun 1 -TI - Role of frailty in patients with cardiovascular disease. -PG - 1616-21 -LID - 10.1016/j.amjcard.2009.01.375 [doi] -AB - Frailty is a geriatric syndrome of increased vulnerability to stressors that has - been implicated as a causative and prognostic factor in patients with - cardiovascular disease (CVD). The American Heart Association and the Society of - Geriatric Cardiology have called for a better understanding of frailty as it - pertains to cardiac care in the elderly. The aim of this study was to - systematically review studies of frailty in patients with CVD. A search was - conducted of Ovid MEDLINE, EMBASE, the Cochrane Database, and unpublished - sources. Inclusion criteria were an assessment of frailty using systematically - defined criteria and a study population with prevalent or incident CVD. Nine - studies were included, encompassing 54,250 elderly patients with a mean weighted - follow-up of 6.2 years. In community-dwelling elders, CVD was associated with an - odds ratio (OR) of 2.7 to 4.1 for prevalent frailty and an OR of 1.5 for incident - frailty in those who were not frail at baseline. Gait velocity (a measure of - frailty) was associated with an OR of 1.6 for incident CVD. In elderly patients - with documented severe coronary artery disease or heart failure, the prevalence - of frailty was 50% to 54%, and this was associated with an OR of 1.6 to 4.0 for - all-cause mortality after adjusting for potential confounders. In conclusion, - there exists a relation between frailty and CVD; frailty may lead to CVD, just as - CVD may lead to frailty. The presence of frailty confers an incremental increase - in mortality. The role of frailty assessment in clinical practice may be to - refine estimates of cardiovascular risk, which tend to be less accurate in the - heterogenous elderly patient population. -FAU - Afilalo, Jonathan -AU - Afilalo J -AD - Division of Cardiology, Sir Mortimer B. Davis Jewish General Hospital, McGill - University, Montreal, Quebec, Canada. jonathan@afilalo.com -FAU - Karunananthan, Sathya -AU - Karunananthan S -FAU - Eisenberg, Mark J -AU - Eisenberg MJ -FAU - Alexander, Karen P -AU - Alexander KP -FAU - Bergman, Howard -AU - Bergman H -LA - eng -PT - Journal Article -PT - Review -DEP - 20090408 -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -SB - IM -MH - Activities of Daily Living -MH - Aged -MH - Body Composition -MH - Cardiovascular Diseases/*epidemiology/mortality/physiopathology -MH - *Frail Elderly -MH - Geriatric Assessment -MH - Humans -RF - 56 -EDAT- 2009/05/26 09:00 -MHDA- 2009/06/19 09:00 -CRDT- 2009/05/26 09:00 -PHST- 2008/11/10 00:00 [received] -PHST- 2009/01/31 00:00 [revised] -PHST- 2009/01/31 00:00 [accepted] -PHST- 2009/05/26 09:00 [entrez] -PHST- 2009/05/26 09:00 [pubmed] -PHST- 2009/06/19 09:00 [medline] -AID - S0002-9149(09)00550-5 [pii] -AID - 10.1016/j.amjcard.2009.01.375 [doi] -PST - ppublish -SO - Am J Cardiol. 2009 Jun 1;103(11):1616-21. doi: 10.1016/j.amjcard.2009.01.375. - Epub 2009 Apr 8. - -PMID- 17907475 -OWN - NLM -STAT- MEDLINE -DCOM- 20071120 -LR - 20191110 -IS - 0095-4829 (Print) -IS - 0095-4829 (Linking) -VI - 32 -DP - 2007 -TI - Spinal cord stimulation for ischemic heart disease and peripheral vascular - disease. -PG - 63-89 -AB - Ischemic disease (ID) is now an important indication for electrical - neuromodulation (NM), particularly in chronic pain conditions. NM is defined as a - therapeutic modality that aims to restore functions of the nervous system or - modulate neural structures involved in the dysfunction of organ systems. One of - the NM methods used is chronic electrical stimulation of the spinal cord (spinal - cord stimulation: SCS). SCS in ID, as applied to ischemic heart disease (IHD) and - peripheral vascular disease (PVD), started in Europe in the 1970s and 1980s, - respectively. Patients with ID are eligible for SCS when they experience - disabling pain, resulting from ischaemia. This pain should be considered - therapeutically refractory to standard treatment intended to decrease metabolic - demand or following revascularization procedures. Several studies have - demonstrated the beneficial effect of SCS on IHD and PVD by improving the quality - of life of this group of severely disabled patients, without adversely - influencing mortality and morbidity. SCS used as additional treatment for IHD - reduces angina pectoris (AP) in its frequency and intensity, increases exercise - capacity, and does not seem to mask the warning signs of a myocardial infarction. - Besides the analgesic effect, different studies have demonstrated an - anti-ischemic effect, as expressed by different cardiac indices such as exercise - duration, ambulatory ECG recording, coronary flow measurements, and PET scans. - SCS can be considered as an alternative to open heart bypass grafting (CABG) for - patients at high risk from surgical procedures. Moreover, SCS appears to be more - efficacious than transcutaneous electrical nerve stimulation (TENS). The SCS - implantation technique is relatively simple: implanting an epidural electrode - under local anesthesia (supervised by the anesthesist) with the tip at T1, - covering the painful area with paraesthesia by external stimulation (pulse width - 210, rate 85 Hz), and connecting this electrode to a subcutaneously implanted - pulse generator. In PVD the pain may manifest itself at rest or during walking - (claudication), disabling the patient severely. Most of the patients suffer from - atherosclerotic critical limb ischemia. All patients should be therapeutically - refractory (medication and revascularization) to become eligible for SCS. Ulcers - on the extremities should be minimal. In PVD the same implantation technique is - used as in IHD except that the tip of the electrode is positioned at T10-11. In - PVD the majority of the patients show significant reduction in pain and more than - half of the patients show improvement of circulatory indices, as shown by - Doppler, thermography, and oximetry studies. Limb salvage studies show variable - results depending on the stage of the trophic changes. The underlying mechanisms - of action of SCS in PVD require further elucidation. -FAU - De Vries, J -AU - De Vries J -AD - Department of Cardiology, Thoraxcenter, University Medical Center Groningen, The - Netherlands. -FAU - De Jongste, M J L -AU - De Jongste MJ -FAU - Spincemaille, G -AU - Spincemaille G -FAU - Staal, M J -AU - Staal MJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Adv Tech Stand Neurosurg -JT - Advances and technical standards in neurosurgery -JID - 7501064 -SB - IM -MH - Electric Stimulation Therapy/instrumentation/*methods -MH - Humans -MH - Myocardial Ischemia/*therapy -MH - Patient Selection -MH - Peripheral Vascular Diseases/*therapy -MH - *Spinal Cord -RF - 84 -EDAT- 2007/10/03 09:00 -MHDA- 2007/12/06 09:00 -CRDT- 2007/10/03 09:00 -PHST- 2007/10/03 09:00 [pubmed] -PHST- 2007/12/06 09:00 [medline] -PHST- 2007/10/03 09:00 [entrez] -AID - 10.1007/978-3-211-47423-5_4 [doi] -PST - ppublish -SO - Adv Tech Stand Neurosurg. 2007;32:63-89. doi: 10.1007/978-3-211-47423-5_4. - -PMID- 19817310 -OWN - NLM -STAT- MEDLINE -DCOM- 20091113 -LR - 20101103 -IS - 2067-2993 (Print) -IS - 2067-2993 (Linking) -VI - 58 -IP - 3 -DP - 2009 Jul-Sep -TI - Smoke free policies in Europe. An overview. -PG - 155-8 -AB - This article is an overview of the current status of implementation of smoke free - legislation in Europe and particularly in Romania. It overviews mostly how these - laws are put to work. Comments are made on the scientific evidence of the harm - induced by second-hand smoking, well known cause of lung cancer, cardiac disease, - low birth weight and chronic respiratory diseases like bronchitis and asthma, - especially in children. In the countries where the smoke free legislation was - successfully implemented (Ireland, Italy, Scotland) there is evidence of reduced - prevalence of the smoking induced diseases, especially acute coronary attacks. - The article emphasizes on the major role of healthcare professionals in reducing - the smoking level, but also on the involvement of politicians, especially the - newly elected Romanians in the European political organisms. -FAU - Kemp, Florence Berteletti -AU - Kemp FB -AD - ERS Headquarters, Brussels Office, Belgium. florence.berteletti@ersnet.org -LA - eng -PT - Journal Article -PT - Review -PL - Romania -TA - Pneumologia -JT - Pneumologia (Bucharest, Romania) -JID - 100941067 -RN - 0 (Tobacco Smoke Pollution) -SB - IM -MH - Asthma/etiology -MH - Bronchitis/etiology -MH - European Union -MH - Evidence-Based Medicine -MH - Female -MH - Government Programs/legislation & jurisprudence -MH - *Health Policy -MH - Heart Diseases/etiology -MH - Humans -MH - Infant, Low Birth Weight -MH - Infant, Newborn -MH - Lung Neoplasms/etiology -MH - *Nurse's Role -MH - *Physician's Role -MH - Politics -MH - Practice Guidelines as Topic -MH - Pregnancy -MH - Romania -MH - Smoking/*adverse effects/*legislation & jurisprudence -MH - Tobacco Smoke Pollution/*adverse effects/*legislation & jurisprudence -RF - 22 -EDAT- 2009/10/13 06:00 -MHDA- 2009/11/17 06:00 -CRDT- 2009/10/13 06:00 -PHST- 2009/10/13 06:00 [entrez] -PHST- 2009/10/13 06:00 [pubmed] -PHST- 2009/11/17 06:00 [medline] -PST - ppublish -SO - Pneumologia. 2009 Jul-Sep;58(3):155-8. - -PMID- 18033009 -OWN - NLM -STAT- MEDLINE -DCOM- 20080304 -LR - 20090213 -IS - 0003-9683 (Print) -IS - 0003-9683 (Linking) -VI - 100 -IP - 9 -DP - 2007 Sep -TI - Protecting the acutely ischemic myocardium beyond reperfusion therapies: are we - any closer to realizing the dream of infarct size elimination? -PG - 794-802 -AB - Patients currently treated for acute myocardial infarction receive reperfusion - therapy as their only anti-infarct intervention. Although pharmacologic agents - have been evaluated in the past for their ability to salvage ischemic myocardium - when administered at reperfusion, until very recently none has demonstrated clear - efficacy in clinical trials. However, a new generation of interventions has - emerged which protects the heart by activating the reperfusion-induced salvage - kinase (RISK) pathway. Unlike the disappointing results documented with - previously touted putative cardioprotective agents, the preclinical experience - with these newer interventions is very consistent indicating that there is a high - likelihood that they will be effective clinically. Ischemic postconditioning, - which also acts by activating the RISK pathway, has shown marked reduction in - infarct size in small-scale trials. Finally, if a strategy for rapidly cooling - the heart can be devised so that the in-hospital normothermic ischemic time can - be significantly reduced, then infarct size can be even further decreased. In our - opinion it is well within our reach using existing technologies to see the day - when infarction can be virtually eliminated in the patient with acute coronary - occlusion. -FAU - Tissier, R -AU - Tissier R -AD - Ecole nationale vétérinaire d'Alfort, Maisons-Alfort. -FAU - Cohen, M V -AU - Cohen MV -FAU - Downey, J M -AU - Downey JM -LA - eng -GR - HL-20648/HL/NHLBI NIH HHS/United States -GR - HL-50688/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - France -TA - Arch Mal Coeur Vaiss -JT - Archives des maladies du coeur et des vaisseaux -JID - 0406011 -SB - IM -MH - Acute Disease -MH - Humans -MH - Myocardial Infarction/pathology/*therapy -MH - Myocardial Ischemia/therapy -MH - Myocardial Reperfusion -RF - 69 -EDAT- 2007/11/23 09:00 -MHDA- 2008/03/05 09:00 -CRDT- 2007/11/23 09:00 -PHST- 2007/11/23 09:00 [pubmed] -PHST- 2008/03/05 09:00 [medline] -PHST- 2007/11/23 09:00 [entrez] -AID - MDOI-AMCV-09-2007-100-9-0003-9683-101019-200602699 [pii] -PST - ppublish -SO - Arch Mal Coeur Vaiss. 2007 Sep;100(9):794-802. - -PMID- 20159873 -OWN - NLM -STAT- MEDLINE -DCOM- 20100226 -LR - 20220309 -IS - 1538-3598 (Electronic) -IS - 0098-7484 (Linking) -VI - 303 -IP - 7 -DP - 2010 Feb 17 -TI - Association between 9p21 genomic markers and heart disease: a meta-analysis. -PG - 648-56 -LID - 10.1001/jama.2010.118 [doi] -AB - CONTEXT: Associations between chromosome 9p21 single-nucleotide polymorphisms - (SNPs) and heart disease have been reported and replicated. If testing improves - risk assessments using traditional factors, it may provide opportunities to - improve public health. OBJECTIVES: To perform a targeted systematic review of - published literature for effect size, heterogeneity, publication bias, and - strength of evidence and to consider whether testing might provide clinical - utility. DATA SOURCES: Electronic search via HuGE Navigator through January 2009 - and review of reference lists from included articles. STUDY SELECTION: - English-language articles that tested for 9p21 SNPs with coronary heart/artery - disease or myocardial infarction as primary outcomes. Included articles also - provided race, numbers of participants, and data to compute an odds ratio (OR). - Articles were excluded if reporting only intermediate outcomes (eg, - atherosclerosis) or if all participants had existing disease. Twenty-five - articles were initially identified and 16 were included. A follow-up search - identified 6 additional articles. DATA EXTRACTION: Independent extraction was - performed by 2 reviewers and consensus was reached. Credibility of evidence was - assessed using published Venice criteria. DATA SYNTHESIS: Forty-seven distinct - data sets from the 22 articles were analyzed, including 35 872 cases and 95 837 - controls. The summary OR for heart disease among individuals with 2 vs 1 at-risk - alleles was 1.25 (95% confidence interval [CI], 1.21-1.29), with low to moderate - heterogeneity. Age at disease diagnosis was a significant covariate, with ORs of - 1.35 (95% CI, 1.30-1.40) for age 55 years or younger and 1.21 (95% CI, 1.16-1.25) - for age 75 years or younger. For a 65-year-old man, the 10-year heart disease - risk for 2 vs 1 at-risk alleles would be 13.2% vs 11%. For a 40-year-old woman, - the 10-year heart disease risk for 2 vs 1 at-risk alleles would be 2.4% vs 2.0%. - Nearly identical but inverse results were found when comparing 1 vs 0 at-risk - alleles. Three studies showed net reclassification indexes ranging from -0.1% to - 4.8%. CONCLUSION: We found a statistically significant association between 9p21 - SNPs and heart disease that varied by age at disease onset, but the magnitude of - the association was small. -FAU - Palomaki, Glenn E -AU - Palomaki GE -AD - Women and Infants Hospital/Alpert Medical School of Brown University, Providence, - Rhode Island 02903, USA. gpalomaki@ipmms.org -FAU - Melillo, Stephanie -AU - Melillo S -FAU - Bradley, Linda A -AU - Bradley LA -LA - eng -GR - 200-2003-01396-0128/PHS HHS/United States -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, U.S. Gov't, P.H.S. -PT - Systematic Review -PL - United States -TA - JAMA -JT - JAMA -JID - 7501160 -RN - 0 (Genetic Markers) -SB - IM -MH - Adult -MH - Age of Onset -MH - Aged -MH - Aged, 80 and over -MH - Alleles -MH - Case-Control Studies -MH - Chromosomes, Human, Pair 9/*genetics -MH - Female -MH - *Genetic Markers -MH - Genetic Predisposition to Disease -MH - Heart Diseases/*genetics -MH - Humans -MH - Male -MH - Middle Aged -MH - Odds Ratio -MH - *Polymorphism, Single Nucleotide -MH - Risk Assessment -EDAT- 2010/02/18 06:00 -MHDA- 2010/02/27 06:00 -CRDT- 2010/02/18 06:00 -PHST- 2010/02/18 06:00 [entrez] -PHST- 2010/02/18 06:00 [pubmed] -PHST- 2010/02/27 06:00 [medline] -AID - 303/7/648 [pii] -AID - 10.1001/jama.2010.118 [doi] -PST - ppublish -SO - JAMA. 2010 Feb 17;303(7):648-56. doi: 10.1001/jama.2010.118. - -PMID- 20532602 -OWN - NLM -STAT- MEDLINE -DCOM- 20110119 -LR - 20211020 -IS - 1572-8595 (Electronic) -IS - 1383-875X (Linking) -VI - 28 -IP - 3 -DP - 2010 Sep -TI - Do endothelin receptor antagonists have an antiarrhythmic potential during acute - myocardial infarction? Evidence from experimental studies. -PG - 157-65 -LID - 10.1007/s10840-010-9493-5 [doi] -AB - Sudden cardiac death constitutes a major health-related problem. In the majority - of cases, sudden cardiac death is due to ventricular tachyarrhythmias secondary - to acute myocardial infarction. The pathophysiologic chain of events leading to - ventricular tachyarrhythmias after acute coronary occlusion is complex and - incompletely understood. Experimental and clinical studies have indicated that - endothelin-1 production rises markedly very early in the course of myocardial - infarction. Endothelin-1 exerts significant electrophysiologic actions on - ventricular cardiomyocytes and participates in the genesis of ischemic - ventricular tachyarrhythmias. Endothelin-1, acting via two G-protein-coupled - receptors (ETA and ETB), prolongs the action potential duration and increases the - occurrence of spontaneous calcium transients, resulting in early - afterdepolarizations and ventricular tachyarrhythmias via triggered activity. - Moreover, endothelin-1 enhances sympathetic stimulation, a well established - contributor to ventricular arrhythmogenesis during acute myocardial infarction. - Despite these considerations, the therapeutic potential of endothelin receptor - antagonists as antiarrhythmic drugs during myocardial ischemia/infarction is - still under investigation. To date, a number of endothelin-1 receptor antagonists - are available, presenting different degrees of selectivity for ETA and ETB - receptors. The arrhythmogenic effects of endothelin-1 are exerted mainly via - stimulation of the ETA receptors, but the role of ETB receptors remains - controversial, as previous studies have produced conflicting results. This review - summarizes the current state-of-the-art on the role of endothelin-1 in the - genesis of ventricular arrhythmias during acute myocardial infarction and raises - some hypotheses that could be explored in future studies. -FAU - Oikonomidis, Dimitrios L -AU - Oikonomidis DL -AD - Department of Cardiology, University of Ioannina, 1 Stavrou Niarxou Avenue, 45110 - Ioannina, Greece. -FAU - Baltogiannis, Giannis G -AU - Baltogiannis GG -FAU - Kolettis, Theofilos M -AU - Kolettis TM -LA - eng -PT - Journal Article -PT - Review -DEP - 20100608 -PL - Netherlands -TA - J Interv Card Electrophysiol -JT - Journal of interventional cardiac electrophysiology : an international journal of - arrhythmias and pacing -JID - 9708966 -RN - 0 (Endothelin-1) -RN - 0 (Receptor, Endothelin A) -RN - 0 (Receptor, Endothelin B) -RN - 0 (Receptors, Endothelin) -SB - IM -MH - Animals -MH - Coronary Occlusion/complications/physiopathology -MH - Endothelin-1/blood/physiology -MH - Humans -MH - Myocardial Infarction/blood/*complications/etiology/pathology/physiopathology -MH - Receptor, Endothelin A/drug effects/physiology -MH - Receptor, Endothelin B/drug effects/physiology -MH - Receptors, Endothelin/*drug effects -MH - Signal Transduction/physiology -MH - Sympathetic Nervous System/physiopathology -MH - Tachycardia, Ventricular/physiopathology/prevention & control -EDAT- 2010/06/10 06:00 -MHDA- 2011/01/20 06:00 -CRDT- 2010/06/10 06:00 -PHST- 2009/07/28 00:00 [received] -PHST- 2010/05/05 00:00 [accepted] -PHST- 2010/06/10 06:00 [entrez] -PHST- 2010/06/10 06:00 [pubmed] -PHST- 2011/01/20 06:00 [medline] -AID - 10.1007/s10840-010-9493-5 [doi] -PST - ppublish -SO - J Interv Card Electrophysiol. 2010 Sep;28(3):157-65. doi: - 10.1007/s10840-010-9493-5. Epub 2010 Jun 8. - -PMID- 21952525 -OWN - NLM -STAT- MEDLINE -DCOM- 20120510 -LR - 20170306 -VI - 121 -IP - 9 -DP - 2011 Sep -TI - Benefits of antihypertensive drugs when blood pressure is below 140/90 mmHg. -PG - 303-9 -LID - 547 [pii] -AB - Antihypertensive medications are used to lower blood pressure (BP) but, - ultimately, their true value lies in reductions in morbidity and mortality - (cardiovascular, cerebrovascular, and renal diseases). Hypertension is defined - discreetly (generally 140/90 mmHg) but the actual relationship between BP and - adverse cardiac and cerebrovascular outcomes is continuous. Observational studies - have demonstrated a powerful log-linear relationship between BP and mortality due - to ischemic heart disease (IHD) or stroke over the range of 115/75 to 185/115 - mmHg. Clinical trials and meta-analyses have clearly demonstrated benefits of - antihypertensive drugs in nonhypertensive individuals: delay or prevention of the - onset of hypertension and microalbuminuria and reduced morbidity and mortality - from IHD, stroke, and chronic kidney disease. This is not surprising given that - various antihypertensive drug classes have multiple potential beneficial effects. - A persistent concern is that overtreatment of hypertension may increase risk in - individuals with coronary artery disease, but a "J-curve" effect is not - consistently found in clinical studies. The use of antihypertensive drugs in - at-risk individuals who are below the traditional threshold (140/90 mmHg) is - fully justifiable, but the decision requires adequate clinical experience and - judgment and a full assessment of risks and benefits. -FAU - Izzo, Joseph L Jr -AU - Izzo JL Jr -AD - Department of Medicine, State University of New York at Buffalo, Buffalo, New - York, USA. jizzo@buffalo.edu -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Pol Arch Med Wewn -JT - Polskie Archiwum Medycyny Wewnetrznej -JID - 0401225 -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Antihypertensive Agents/*pharmacology/*therapeutic use -MH - Blood Pressure/*drug effects -MH - Cardiovascular Diseases/*prevention & control -MH - Humans -MH - Hypertension/*drug therapy -MH - Treatment Outcome -EDAT- 2011/09/29 06:00 -MHDA- 2012/05/11 06:00 -CRDT- 2011/09/29 06:00 -PHST- 2011/09/29 06:00 [entrez] -PHST- 2011/09/29 06:00 [pubmed] -PHST- 2012/05/11 06:00 [medline] -AID - 547 [pii] -PST - ppublish -SO - Pol Arch Med Wewn. 2011 Sep;121(9):303-9. - -PMID- 18200802 -OWN - NLM -STAT- MEDLINE -DCOM- 20080225 -LR - 20241102 -IS - 1176-6344 (Print) -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Linking) -VI - 3 -IP - 6 -DP - 2007 -TI - Obesity management: update on orlistat. -PG - 817-21 -AB - Over the past 20 years obesity has become a worldwide concern of frightening - proportion. The World Health Organization estimates that there are over 400 - million obese and over 1.6 billion overweight adults, a figure which is projected - to almost double by 2015. This is not a disease restricted to adults - at least - 20 million children under the age of 5 years were overweight in 2005 (WHO 2006). - Overweight and obesity lead to serious health consequences including coronary - artery disease, stroke, type-2 diabetes, heart failure, dyslipidemia, - hypertension, reproductive and gastrointestinal cancers, gallstones, fatty liver - disease, osteoarthritis and sleep apnea (Padwal et al 2003). Modest weight loss - in the obese of between 5% and 10% of bodyweight is associated with improvements - in cardiovascular risk profiles and reduced incidence of type 2 diabetes - (Goldstein 1992; Avenell et al 2004; Padwal and Majumdar 2007). Orlistat, a - gastric and pancreatic lipase inhibitor that reduces dietary fat absorption by - approximately 30%, has been approved for use for around ten years (Zhi et al - 1994; Hauptman 2000). There is now a growing body of evidence to suggest that - Orlistat assists weight loss and that it may also have additional benefits. The - aim of this review is to provide a brief update on the current literature - studying the efficacy, safety and significance of the use of Orlistat in clinical - practice. -FAU - Drew, Belinda S -AU - Drew BS -AD - Centre for Obesity Research and Education, Monash University, Melbourne, - Victoria, Australia. -FAU - Dixon, Andrew F -AU - Dixon AF -FAU - Dixon, John B -AU - Dixon JB -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -RN - 0 (Anti-Obesity Agents) -RN - 0 (Lactones) -RN - 95M8R751W8 (Orlistat) -SB - IM -MH - Anti-Obesity Agents/*therapeutic use -MH - Comorbidity -MH - Drug Interactions -MH - Humans -MH - Lactones/*therapeutic use -MH - Obesity/*drug therapy -MH - Orlistat -MH - Patient Compliance -MH - Weight Loss -PMC - PMC2350121 -EDAT- 2008/01/19 09:00 -MHDA- 2008/02/26 09:00 -CRDT- 2008/01/19 09:00 -PHST- 2008/01/19 09:00 [pubmed] -PHST- 2008/02/26 09:00 [medline] -PHST- 2008/01/19 09:00 [entrez] -PST - ppublish -SO - Vasc Health Risk Manag. 2007;3(6):817-21. - -PMID- 20036804 -OWN - NLM -STAT- MEDLINE -DCOM- 20100423 -LR - 20220225 -IS - 2768-6698 (Electronic) -IS - 2768-6698 (Linking) -VI - 15 -IP - 1 -DP - 2010 Jan 1 -TI - The emerging role of telomere biology in cardiovascular disease. -PG - 35-45 -AB - A striking variability exists in the susceptibility, age of onset and pace of - progression of cardiovascular diseases. This is inadequately explained by the - presence or absence of conventional risk factors. Differences in biological aging - might provide an additional component of the observed variability. Telomere - length provides a potential marker of an individual's biological age, shorter - telomeres reflect a more advanced biological age. Telomere length at birth is - mainly determined by genetic factors. Telomere attrition occurs as a consequence - of cellular replication and can be accelerated by harmful environmental factors - such as oxidative stress. When telomeres reach a critical threshold the cell will - enter senescence and becomes dysfunctional. Telomeres are remarkably shorter in - patients with aging associated diseases, including coronary artery disease and - chronic heart failure. In addition, numerous conventional cardiovascular risk - factors are associated with shorter telomere length. If telomeres can be proven - to be not only associated but also causally involved in the pathogenesis of - cardiovascular disease it might provide exciting new avenues for the development - of future preventive and therapeutic strategies. -FAU - Huzen, Jardi -AU - Huzen J -AD - Department of Cardiology, University Medical Centre Groningen, University of - Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands. - j.huzen@thorax.umcg.nl -FAU - de Boer, Rudolf A -AU - de Boer RA -FAU - van Veldhuisen, Dirk J -AU - van Veldhuisen DJ -FAU - van Gilst, Wiek H -AU - van Gilst WH -FAU - van der Harst, Pim -AU - van der Harst P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100101 -PL - Singapore -TA - Front Biosci (Landmark Ed) -JT - Frontiers in bioscience (Landmark edition) -JID - 101612996 -SB - IM -MH - Aging/*physiology -MH - Animals -MH - Cardiovascular Diseases/drug therapy/*genetics/physiopathology -MH - DNA Repair/drug effects -MH - Exercise/physiology -MH - Humans -MH - Models, Biological -MH - Telomere/drug effects/*genetics -RF - 85 -EDAT- 2009/12/29 06:00 -MHDA- 2010/04/24 06:00 -CRDT- 2009/12/29 06:00 -PHST- 2009/12/29 06:00 [entrez] -PHST- 2009/12/29 06:00 [pubmed] -PHST- 2010/04/24 06:00 [medline] -AID - 3604 [pii] -AID - 10.2741/3604 [doi] -PST - epublish -SO - Front Biosci (Landmark Ed). 2010 Jan 1;15(1):35-45. doi: 10.2741/3604. - -PMID- 20560027 -OWN - NLM -STAT- MEDLINE -DCOM- 20101004 -LR - 20211020 -IS - 1937-5395 (Electronic) -IS - 1937-5387 (Linking) -VI - 3 -IP - 2 -DP - 2010 Apr -TI - Intramyocardial navigation and mapping for stem cell delivery. -PG - 135-46 -LID - 10.1007/s12265-009-9138-1 [doi] -AB - Method for delivery remains a central component of stem cell-based cardiovascular - research. Comparative studies have demonstrated the advantages of administering - cell therapy directly into the myocardium, as distinct from infusing cells into - the systemic or coronary vasculature. Intramyocardial delivery can be achieved - either transepicardially or transendocardially. The latter involves percutaneous, - femoral arterial access and the retrograde passage of specially designed - injection catheters into the left ventricle, making it less invasive and more - relevant to wider clinical practice. Imaging-based navigation plays an important - role in guiding catheter manipulation and directing endomyocardial injections. - The most established strategy for three-dimensional, intracardiac navigation is - currently endoventricular, electromechanical mapping, which offers superior - spatial orientation compared to simple x-ray fluoroscopy. Its provision of - point-by-point, electrophysiologic and motion data also allows characterization - of regional myocardial viability, perfusion, and function, especially in the - setting of ischemic heart disease. Integrating the mapping catheter with an - injection port enables this diagnostic information to facilitate the targeting of - intramyocardial stem cell delivery. This review discusses the diagnostic accuracy - and expanding therapeutic application of electromechanical navigation in - cell-based research and describes exciting developments which will improve the - technology's sensing capabilities, image registration, and delivery precision in - the near future. -FAU - Psaltis, Peter J -AU - Psaltis PJ -AD - Cardiovascular Research Centre, Department of Cardiology, Royal Adelaide Hospital - and the Department of Medicine, University of Adelaide, Adelaide, South - Australia, 5000, Australia. peter.psaltis@adelaide.edu.au -FAU - Zannettino, Andrew C W -AU - Zannettino AC -FAU - Gronthos, Stan -AU - Gronthos S -FAU - Worthley, Stephen G -AU - Worthley SG -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20091023 -PL - United States -TA - J Cardiovasc Transl Res -JT - Journal of cardiovascular translational research -JID - 101468585 -SB - IM -MH - Animals -MH - *Cardiac Catheterization/instrumentation -MH - Equipment Design -MH - Heart Diseases/pathology/physiopathology/*surgery -MH - Humans -MH - Myocardium/*pathology -MH - Regeneration -MH - Stem Cell Transplantation/instrumentation/*methods -MH - *Surgery, Computer-Assisted/instrumentation -MH - Treatment Outcome -RF - 78 -EDAT- 2010/06/19 06:00 -MHDA- 2010/10/05 06:00 -CRDT- 2010/06/19 06:00 -PHST- 2009/09/05 00:00 [received] -PHST- 2009/09/28 00:00 [accepted] -PHST- 2010/06/19 06:00 [entrez] -PHST- 2010/06/19 06:00 [pubmed] -PHST- 2010/10/05 06:00 [medline] -AID - 10.1007/s12265-009-9138-1 [doi] -PST - ppublish -SO - J Cardiovasc Transl Res. 2010 Apr;3(2):135-46. doi: 10.1007/s12265-009-9138-1. - Epub 2009 Oct 23. - -PMID- 16860886 -OWN - NLM -STAT- MEDLINE -DCOM- 20070501 -LR - 20151119 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 117 -IP - 1 -DP - 2007 Apr 12 -TI - Exercise-induced cardioprotection--biochemical, morphological and functional - evidence in whole tissue and isolated mitochondria. -PG - 16-30 -AB - Myocardial injury is a major contributor to the morbidity and mortality - associated with coronary artery disease. Regular exercise has been confirmed as a - pragmatic countermeasure to protect against cardiac injury. Specifically, - endurance exercise has been proven to provide cardioprotection against cardiac - insults in both young and old animals. Proposed mechanisms to explain the - cardioprotective effects of exercise are mediated, at least partially, by redox - changes and include the induction of myocardial heat shock proteins, improved - cardiac antioxidant capacity, and/or elevation of other cardioprotective - molecules. Understanding the molecular basis for exercise-induced - cardioprotection is important in developing exercise strategies to protect the - heart during and after insults. Data suggest that these positive modulator - effects occur at different levels of cellular organization, being mitochondria - fundamental organelles that are sensitive to disturbances imposed by exercise on - basal homeostasis. At present, which of these protective mechanisms is essential - for exercise-induced cardioprotection remains unclear. This review analyzes the - biochemical, morphological and functional outcomes of acute and chronic exercise - on the overall cardiac muscle tissue and in isolated mitochondria. Some - redox-based mechanisms behind the cross-tolerance effects particularly induced by - endurance training, against certain stressors responsible for the impairments in - cardiac homeostasis caused by aging, diabetes, drug administration or - ischemia-reperfusion are also outlined. Further work should be addressed in order - to clarify the precise regulatory mechanisms by which physical exercise augments - heart tolerance against many cardiotoxic agents. -FAU - Ascensão, António -AU - Ascensão A -AD - Department of Sports Biology, Research Center in Physical Activity, Health and - Leisure, Faculty of Sport Sciences, University of Porto, Rua Dr. Plácido Costa, - 91, 4200-450 Porto, Portugal. aascensao@fcdef.up.pt -FAU - Ferreira, Rita -AU - Ferreira R -FAU - Magalhães, José -AU - Magalhães J -LA - eng -PT - Journal Article -PT - Review -DEP - 20060724 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Antioxidants) -RN - 0 (Biomarkers) -RN - 0 (Heat-Shock Proteins) -SB - IM -MH - Animals -MH - Antioxidants/metabolism -MH - Biomarkers/blood -MH - Exercise/*physiology -MH - Heart/*physiology -MH - Heart Diseases/*prevention & control -MH - Heart Function Tests -MH - Heat-Shock Proteins/metabolism -MH - Humans -MH - Myocardium/metabolism -MH - Oxidation-Reduction -MH - Oxidative Stress/physiology -MH - Physical Endurance/physiology -RF - 139 -EDAT- 2006/07/25 09:00 -MHDA- 2007/05/02 09:00 -CRDT- 2006/07/25 09:00 -PHST- 2005/12/09 00:00 [received] -PHST- 2006/04/06 00:00 [revised] -PHST- 2006/04/28 00:00 [accepted] -PHST- 2006/07/25 09:00 [pubmed] -PHST- 2007/05/02 09:00 [medline] -PHST- 2006/07/25 09:00 [entrez] -AID - S0167-5273(06)00544-4 [pii] -AID - 10.1016/j.ijcard.2006.04.076 [doi] -PST - ppublish -SO - Int J Cardiol. 2007 Apr 12;117(1):16-30. doi: 10.1016/j.ijcard.2006.04.076. Epub - 2006 Jul 24. - -PMID- 18243853 -OWN - NLM -STAT- MEDLINE -DCOM- 20080306 -LR - 20151119 -IS - 0002-9149 (Print) -IS - 0002-9149 (Linking) -VI - 101 -IP - 3A -DP - 2008 Feb 4 -TI - Amino-terminal pro-B-type natriuretic peptide testing in patients with diabetes - mellitus and with systemic hypertension. -PG - 21-4 -LID - 10.1016/j.amjcard.2007.11.015 [doi] -AB - Although the current value of amino-terminal pro-B-type natriuretic peptides - (NT-proBNP) to generally screen populations of "apparently well patients" remains - promising but still undefined, the use of NT-proBNP to screen patients at high - risk for heart disease (such as elderly patients, or patients with diabetes - mellitus, hypertension, or known coronary artery disease) appears logical and is - supported by data. NT-proBNP has strong prognostic value in such at-risk - patients. However, the exact implications for clinical management after detection - of an elevated NT-proBNP value should be driven by clinical judgment. At present, - data suggest that when an elevated NT-proBNP is detected in an at-risk patient, - it is a high-risk finding. In this context, consideration for a more in-depth - cardiovascular workup, as well as initiation or intensification of medical - therapies with proven benefits might be indicated. -FAU - Hildebrandt, Per -AU - Hildebrandt P -AD - Department of Internal Medicine and Cardiology, Roskilde University Hospital, - Roskilde, Denmark. -FAU - Richards, A Mark -AU - Richards AM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -RN - 0 (Biomarkers) -RN - 0 (Peptide Fragments) -RN - 0 (Protein Precursors) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Biomarkers/blood -MH - Diabetes Mellitus/*blood -MH - Humans -MH - Hypertension/*blood -MH - Mass Screening/*methods -MH - Natriuretic Peptide, Brain/*blood -MH - Peptide Fragments/*blood -MH - Prognosis -MH - Protein Precursors -MH - Risk Factors -RF - 19 -EDAT- 2008/02/22 09:00 -MHDA- 2008/03/07 09:00 -CRDT- 2008/02/22 09:00 -PHST- 2008/02/22 09:00 [pubmed] -PHST- 2008/03/07 09:00 [medline] -PHST- 2008/02/22 09:00 [entrez] -AID - S0002-9149(07)02240-0 [pii] -AID - 10.1016/j.amjcard.2007.11.015 [doi] -PST - ppublish -SO - Am J Cardiol. 2008 Feb 4;101(3A):21-4. doi: 10.1016/j.amjcard.2007.11.015. - -PMID- 21519250 -OWN - NLM -STAT- MEDLINE -DCOM- 20111024 -LR - 20110712 -IS - 1473-6535 (Electronic) -IS - 0957-9672 (Linking) -VI - 22 -IP - 4 -DP - 2011 Aug -TI - Hyperlipidaemia and cardiovascular disease: do fibrates have a role? -PG - 270-6 -LID - 10.1097/MOL.0b013e32834701c3 [doi] -AB - PURPOSE OF REVIEW: Fibrates continue to be a viable treatment option for mixed - atherogenic dyslipidemia, and recent reports from clinical studies have shed new - light on the therapeutic utility of fibrates for the prevention of microvascular - and macrovascular disease, especially in combination with statins. RECENT - FINDINGS: Data from randomized placebo-controlled trials have shown that fibrates - reduce nonfatal coronary events but do not confer any benefit on mortality or - other adverse cardiovascular outcomes. The ACCORD Lipid trial studied the - additive effect of fenofibrate therapy along with low-dose simvastatin therapy in - 5,518 patients with type 2 diabetes mellitus, and found that fenofibrate did not - affect any of the adverse cardiovascular outcomes, either individually or as part - of a composite outcome, after 4.7 years of follow-up. An a priori subgroup - analysis showed a significant benefit from fenofibrate-simvastatin combination - therapy over simvastatin alone in participants with moderate hypertriglyceridemia - and low HDL-cholesterol on major cardiovascular events, consistent with post-hoc - analyses of previous fibrate trials. The ACCORD-Eye study adds to the sparse - clinical data on the effect of fenofibrate on diabetic retinopathy, and showed - that fenofibrate may be used to reduce the risk of progression of diabetic - retinopathy even in patients with established disease. The combination of statin - and fibrate was well tolerated. SUMMARY: Fibrate therapy does not reduce - mortality but may reduce nonfatal coronary events in patients at risk for - cardiovascular disease, including those with type 2 diabetes. The ACCORD Lipid - study shows that the combination of low-dose simvastatin and fenofibrate is well - tolerated, and is potentially cardioprotective in patients with atherogenic - 'mixed' dyslipidemia. -FAU - Saha, Sandeep A -AU - Saha SA -AD - Providence Sacred Heart Medical Center, Spokane, WA 99220-2555, USA. sahas@uw.edu -FAU - Arora, Rohit R -AU - Arora RR -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Curr Opin Lipidol -JT - Current opinion in lipidology -JID - 9010000 -RN - 0 (Fibric Acids) -SB - IM -MH - Cardiovascular Diseases/*etiology -MH - Diabetes Mellitus, Type 2/complications/drug therapy -MH - Diabetic Retinopathy/drug therapy -MH - Drug Therapy, Combination -MH - Fibric Acids/adverse effects/pharmacology/*therapeutic use -MH - Humans -MH - Hyperlipidemias/*complications/drug therapy -MH - Meta-Analysis as Topic -MH - Microvessels/drug effects/pathology -MH - Randomized Controlled Trials as Topic -EDAT- 2011/04/27 06:00 -MHDA- 2011/10/25 06:00 -CRDT- 2011/04/27 06:00 -PHST- 2011/04/27 06:00 [entrez] -PHST- 2011/04/27 06:00 [pubmed] -PHST- 2011/10/25 06:00 [medline] -AID - 10.1097/MOL.0b013e32834701c3 [doi] -PST - ppublish -SO - Curr Opin Lipidol. 2011 Aug;22(4):270-6. doi: 10.1097/MOL.0b013e32834701c3. - -PMID- 16624609 -OWN - NLM -STAT- MEDLINE -DCOM- 20061207 -LR - 20161124 -IS - 1096-6374 (Print) -IS - 1096-6374 (Linking) -VI - 16 Suppl A -DP - 2006 Jul -TI - Renal osteodystrophy in children: a systemic disease associated with - cardiovascular manifestations. -PG - S79-83 -AB - The increasing prevalence of chronic kidney disease (CKD) in the United States - demands a closer evaluation of and attention to associated morbidities, and, - particularly, the rising mortality related to cardiovascular disease in all age - groups. Patients with CKD demonstrate an increased risk of coronary artery - disease due to calcium deposition and subsequent arterial stiffening, in addition - to left ventricular dysfunction with associated heart failure and arrhythmias. - While clearly impacted by the traditional risk factors for development of - cardiovascular disease (CVD), patients with CKD are also affected by - non-traditional risk factors, including calcium overloading related to aggressive - management of secondary hyperparathyroidism. Recent data have shown that a - substantial number of patients with CKD are deficient in vitamin D on a - nutritional basis, in addition to the known decrease in the kidney-produced - active metabolite during progressive CKD. Historically, vitamin D has been - described as an endocrine hormone that regulates blood calcium and parathyroid - hormone levels. It has become increasingly clear, through the recognition of a - vitamin D receptor in most tissues, that vitamin D possesses functions well - beyond calcium homeostasis, such that a deficiency may contribute to the - development of CVD. In this brief review, the role of vitamin D activation - through its vitamin D receptor will serve as an introduction to the magnitude of - the nutritional deficits in children, adults, and those with CKD. As therapeutic - entities in the management of renal osteodystrophy, vitamin D analogues play an - important role in cardiovascular health that continues to evolve. Preliminary - studies indicate that vitamin D therapy for control of secondary - hyperparathyroidism may confer cardioprotection and reduce mortality. Attention - to care of osteodystrophy in CKD must take into account heart health as well. -FAU - Langman, Craig B -AU - Langman CB -AD - Children's Memorial Hospital, 2300 Children's Plaza, MS #37, Chicago, IL 60614, - USA. c-lamgman@northwestern.edu -FAU - Brooks, Ellen R -AU - Brooks ER -LA - eng -PT - Journal Article -PT - Review -DEP - 20060418 -PL - Scotland -TA - Growth Horm IGF Res -JT - Growth hormone & IGF research : official journal of the Growth Hormone Research - Society and the International IGF Research Society -JID - 9814320 -SB - IM -MH - Cardiovascular Diseases/drug therapy/*etiology -MH - Child -MH - Chronic Kidney Disease-Mineral and Bone Disorder/*complications/drug therapy -MH - Humans -MH - Nutritional Physiological Phenomena -MH - Renal Insufficiency, Chronic/epidemiology -MH - Vitamin D Deficiency/drug therapy -RF - 26 -EDAT- 2006/04/21 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/04/21 09:00 -PHST- 2006/04/21 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/04/21 09:00 [entrez] -AID - S1096-6374(06)00028-1 [pii] -AID - 10.1016/j.ghir.2006.03.003 [doi] -PST - ppublish -SO - Growth Horm IGF Res. 2006 Jul;16 Suppl A:S79-83. doi: 10.1016/j.ghir.2006.03.003. - Epub 2006 Apr 18. - -PMID- 18599065 -OWN - NLM -STAT- MEDLINE -DCOM- 20090810 -LR - 20220317 -IS - 1879-1484 (Electronic) -IS - 0021-9150 (Linking) -VI - 201 -IP - 2 -DP - 2008 Dec -TI - Role of inflammation and oxidative stress in endothelial progenitor cell function - and mobilization: therapeutic implications for cardiovascular diseases. -PG - 236-47 -LID - 10.1016/j.atherosclerosis.2008.05.034 [doi] -AB - Endothelial progenitor cells (EPCs) are mobilized from the bone marrow into the - peripheral circulation, home to sites of injury, and incorporate into foci of - neovascularization, thereby improving blood flow and tissue recovery. Patients - with cardiovascular diseases, including coronary artery disease, heart failure, - hypertension, and diabetes, have been shown to exhibit reduced number and - functional capacity of EPCs. Considerable evidence indicates that EPCs constitute - an important endogenous system to maintain endothelial integrity and vascular - homeostasis, while reduced number of EPCs has recently been shown to predict - future cardiovascular events. Thus, enhancement of EPCs could be of potential - benefit for individuals with cardiovascular diseases. The interplay between - inflammation and oxidative stress is involved in the initiation, progression, and - complications of cardiovascular diseases. Emerging evidence from in vitro and - clinical studies suggests that inflammatory and oxidative changes influence EPC - mobilization. Drugs with anti-inflammatory and antioxidant properties, currently - administered to patients with cardiovascular diseases, such as statins, have been - demonstrated to exert beneficial effects on EPC biology. A better understanding - of the inflammatory and oxidative mechanisms leading to the numerical and - functional impairment of EPCs would provide additional insight into the - pathogenesis of cardiovascular disease and create novel therapeutic targets. -FAU - Tousoulis, Dimitris -AU - Tousoulis D -AD - A' Cardiology Department, Hippokration Hospital, Athens University Medical - School, Athens, Greece. drtousoulis@hotmail.com -FAU - Andreou, Ioannis -AU - Andreou I -FAU - Antoniades, Charalambos -AU - Antoniades C -FAU - Tentolouris, Costas -AU - Tentolouris C -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -DEP - 20080528 -PL - Ireland -TA - Atherosclerosis -JT - Atherosclerosis -JID - 0242543 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Antioxidants) -RN - 0 (Free Radicals) -RN - 0 (PPAR gamma) -SB - IM -MH - Angiotensin-Converting Enzyme Inhibitors/metabolism -MH - Animals -MH - Antioxidants/metabolism -MH - Cardiovascular Diseases/*metabolism/pathology -MH - Disease Models, Animal -MH - Endothelial Cells/*cytology -MH - Free Radicals -MH - Humans -MH - *Inflammation -MH - Models, Biological -MH - Oxidation-Reduction -MH - *Oxidative Stress -MH - PPAR gamma/metabolism -MH - Stem Cells/*cytology -RF - 80 -EDAT- 2008/07/05 09:00 -MHDA- 2009/08/11 09:00 -CRDT- 2008/07/05 09:00 -PHST- 2007/11/20 00:00 [received] -PHST- 2008/05/08 00:00 [revised] -PHST- 2008/05/13 00:00 [accepted] -PHST- 2008/07/05 09:00 [pubmed] -PHST- 2009/08/11 09:00 [medline] -PHST- 2008/07/05 09:00 [entrez] -AID - S0021-9150(08)00355-9 [pii] -AID - 10.1016/j.atherosclerosis.2008.05.034 [doi] -PST - ppublish -SO - Atherosclerosis. 2008 Dec;201(2):236-47. doi: - 10.1016/j.atherosclerosis.2008.05.034. Epub 2008 May 28. - -PMID- 23739939 -OWN - NLM -STAT- MEDLINE -DCOM- 20140113 -LR - 20220409 -VI - 28 -IP - 1 -DP - 2013 Mar -TI - Religion, spirituality and cardiovascular disease: research, clinical - implications, and opportunities in Brazil. -PG - 103-28 -LID - S0102-76382013000100015 [pii] -LID - 10.5935/1678-9741.20130015 [doi] -AB - In this paper we comprehensively review published quantitative research on the - relationship between religion, spirituality (R/S), and cardiovascular (CV) - disease, discuss mechanisms that help explain the associations reported, examine - the clinical implications of those findings, and explore future research needed - in Brazil on this topic. First, we define the terms religion, spirituality, and - secular humanism. Next, we review research examining the relationships between - R/S and CV risk factors (smoking, alcohol/drug use, physical inactivity, poor - diet, cholesterol, obesity, diabetes, blood pressure, and psychosocial stress). - We then review research on R/S, cardiovascular functions (CV reactivity, heart - rate variability, etc.), and inflammatory markers (IL-6, IFN-γ, CRP, fibrinogen, - IL-4, IL-10). Next we examine research on R/S and coronary artery disease, - hypertension, stroke, dementia, cardiac surgery outcomes, and mortality (CV - mortality in particular). We then discuss mechanisms that help explain these - relationships (focusing on psychological, social, and behavioral pathways) and - present a theoretical causal model based on a Western religious perspective. Next - we discuss the clinical applications of the research, and make practical - suggestions on how cardiologists and cardiac surgeons can sensitively and - sensibly address spiritual issues in clinical practice. Finally, we explore - opportunities for future research. No research on R/S and cardiovascular disease - has yet been published from Brazil, despite the tremendous interest and - involvement of the population in R/S, making this an area of almost unlimited - possibilities for researchers in Brazil. -FAU - Lucchese, Fernando A -AU - Lucchese FA -AD - Hospital São Francisco (Cardiology and Transplants), Porto Alegre, RS, Brazil. -FAU - Koenig, Harold G -AU - Koenig HG -LA - eng -PT - Journal Article -PT - Review -PL - Brazil -TA - Rev Bras Cir Cardiovasc -JT - Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade - Brasileira de Cirurgia Cardiovascular -JID - 9104279 -SB - IM -MH - Biomedical Research -MH - Brazil -MH - *Cardiovascular Diseases/physiopathology/psychology -MH - Cardiovascular Surgical Procedures -MH - *Humanism -MH - Humans -MH - *Religion -MH - Risk Factors -MH - Self Efficacy -MH - *Spirituality -MH - Treatment Outcome -EDAT- 2013/06/07 06:00 -MHDA- 2014/01/15 06:00 -CRDT- 2013/06/07 06:00 -PHST- 2012/12/05 00:00 [received] -PHST- 2013/02/12 00:00 [accepted] -PHST- 2013/06/07 06:00 [entrez] -PHST- 2013/06/07 06:00 [pubmed] -PHST- 2014/01/15 06:00 [medline] -AID - S0102-76382013000100015 [pii] -AID - 10.5935/1678-9741.20130015 [doi] -PST - ppublish -SO - Rev Bras Cir Cardiovasc. 2013 Mar;28(1):103-28. doi: 10.5935/1678-9741.20130015. - -PMID- 22989426 -OWN - NLM -STAT- MEDLINE -DCOM- 20130226 -LR - 20220409 -IS - 1462-0332 (Electronic) -IS - 1462-0324 (Linking) -VI - 52 -IP - 1 -DP - 2013 Jan -TI - Obesity and psoriatic arthritis: from pathogenesis to clinical outcome and - management. -PG - 62-7 -LID - 10.1093/rheumatology/kes242 [doi] -AB - PsA is an axial and/or peripheral inflammatory arthritis associated with - psoriasis, included in the group of spondylarthritides. It has been suggested - that PsA could be a systemic disease, involving even coronary arteries and the - heart. An increased prevalence of vascular risk factors has been found in PsA - subjects as compared with the general population and psoriatic subjects. - Moreover, PsA patients exhibit an increased prevalence of liver steatosis, a - marker of metabolic syndrome, and of obesity. Interestingly, many reports - demonstrate that adipose tissue is metabolically active, representing a source of - inflammatory mediators, known as adipokines. The latter include TNF-α, macrophage - chemoattractant protein-1, plasminogen activator inhibitor-1 (PAI-1), IL-6, - leptin and adiponectin, leading to a pro-inflammatory status in obese subjects. - This evidence supports the idea of obesity as a low-grade inflammatory disease. - Accordingly, obesity might be associated with some rheumatic diseases. In - particular, it seems to affect several features of PsA, such as its development, - cardiovascular risk and clinical outcome. Recent data suggest that increased BMI - in early adulthood increases the risk of PsA development in psoriatic patients, - supporting a link between fat-mediated inflammation and joint involvement. - Obesity may represent an additive cardio-metabolic risk factor in PsA subjects. - Abdominal obesity may also determine an increased risk of not achieving minimal - disease activity in PsA patients, highlighting the role of abdominal fat - accumulation as a negative predictor of good clinical response to biologic - agents. This review assesses the relationship between obesity and PsA according - to the available literature. -FAU - Russolillo, Anna -AU - Russolillo A -AD - Department of Clinical and Experimental Medicine, Rheumatology Research Unit, - 'Federico II' University, Naples, Italy. -FAU - Iervolino, Salvatore -AU - Iervolino S -FAU - Peluso, Rosario -AU - Peluso R -FAU - Lupoli, Roberta -AU - Lupoli R -FAU - Di Minno, Alessandro -AU - Di Minno A -FAU - Pappone, Nicola -AU - Pappone N -FAU - Di Minno, Matteo Nicola Dario -AU - Di Minno MN -LA - eng -PT - Journal Article -PT - Review -DEP - 20120918 -PL - England -TA - Rheumatology (Oxford) -JT - Rheumatology (Oxford, England) -JID - 100883501 -SB - IM -MH - Arthritis, Psoriatic/*complications/drug therapy -MH - Disease Management -MH - Humans -MH - Inflammation/complications -MH - Obesity/*complications/drug therapy -EDAT- 2012/09/20 06:00 -MHDA- 2013/02/27 06:00 -CRDT- 2012/09/20 06:00 -PHST- 2012/09/20 06:00 [entrez] -PHST- 2012/09/20 06:00 [pubmed] -PHST- 2013/02/27 06:00 [medline] -AID - kes242 [pii] -AID - 10.1093/rheumatology/kes242 [doi] -PST - ppublish -SO - Rheumatology (Oxford). 2013 Jan;52(1):62-7. doi: 10.1093/rheumatology/kes242. - Epub 2012 Sep 18. - -PMID- 22870586 -OWN - NLM -STAT- MEDLINE -DCOM- 20120828 -LR - 20191112 -IS - 0065-2423 (Print) -IS - 0065-2423 (Linking) -VI - 57 -DP - 2012 -TI - Biomarkers in hemodialysis patients. -PG - 29-56 -AB - Patients with chronic kidney disease (CKD) are, compared to the general - population, at higher risk of cardiovascular disease (CVD), including sudden - death, coronary artery disease (CAD), congestive heart failure (HF), stroke, and - peripheral artery disease. The presence of CVD is independently associated with - kidney function decline. Renal insufficiency is a strong and independent - predictor of mortality in patients with different CKD stages. The interplay of - traditional and nontraditional risk factors is complex such that risk factor - profiles are different in CKD patients. Seemingly, paradoxical associations - between traditional risk factors and cardiovascular outcome complicate efforts to - identify real cardiovascular etiology in these patients. Additional tools are - often required to aid clinical assessment of cardiovascular risk. Recently, a - number of cardiovascular biomarkers were identified as predictors of outcome in - CVD. These may be used to guide early diagnosis and therapy for CVD or may - predict outcome in CKD. This review focuses on the potential diagnostic and - prognostic use of some important new biomarkers including brain natriuretic - peptide (BNP), cardiac troponins (cTns), inflammatory markers, adhesion - molecules, and asymmetric dimethylarginine (ADMA) in CKD as well as those - patients with end-stage renal failure. -FAU - Hojs, Radovan -AU - Hojs R -AD - Department of Nephrology, Clinic of Internal Medicine, University Medical Centre, - Maribor, Slovenia. radovan.hojs@guest.arnes.si -FAU - Bevc, Sebastjan -AU - Bevc S -FAU - Ekart, Robert -AU - Ekart R -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Adv Clin Chem -JT - Advances in clinical chemistry -JID - 2985173R -RN - 0 (Biomarkers) -RN - 0 (Cell Adhesion Molecules) -RN - 0 (Troponin) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - 63CV1GEK3Y (N,N-dimethylarginine) -RN - 94ZLA3W45F (Arginine) -SB - IM -MH - Animals -MH - Arginine/analogs & derivatives/analysis -MH - Biomarkers/*analysis -MH - Cardiovascular Physiological Phenomena -MH - Cell Adhesion Molecules/analysis -MH - Humans -MH - Inflammation/metabolism -MH - Kidney Failure, Chronic/blood/therapy -MH - Natriuretic Peptide, Brain/analysis -MH - *Renal Dialysis -MH - Troponin/analysis -EDAT- 2012/08/09 06:00 -MHDA- 2012/08/29 06:00 -CRDT- 2012/08/09 06:00 -PHST- 2012/08/09 06:00 [entrez] -PHST- 2012/08/09 06:00 [pubmed] -PHST- 2012/08/29 06:00 [medline] -AID - 10.1016/b978-0-12-394384-2.00002-4 [doi] -PST - ppublish -SO - Adv Clin Chem. 2012;57:29-56. doi: 10.1016/b978-0-12-394384-2.00002-4. - -PMID- 16946285 -OWN - NLM -STAT- MEDLINE -DCOM- 20061228 -LR - 20071115 -IS - 1553-2712 (Electronic) -IS - 1069-6563 (Linking) -VI - 13 -IP - 12 -DP - 2006 Dec -TI - Care for the adult family members of victims of unexpected cardiac death. -PG - 1333-8 -AB - More than 300,000 sudden coronary deaths occur annually in the United States, - despite declining cardiovascular death rates. In 2000, deaths from heart disease - left an estimated 190,156 new widows and 68,493 new widowers. A major unanswered - question for emergency providers is whether the immediate care of the loved ones - left behind by the deceased should be a therapeutic task for the staff of the - emergency department in the aftermath of a fatal cardiac arrest. Based on a - review of the literature, the authors suggest that more research is needed to - answer this question, to assess the current immediate needs and care of - survivors, and to find ways to improve care of the surviving family of unexpected - cardiac death victims. This would include improving quality of death disclosure, - improving care for relatives during cardiopulmonary resuscitation of their family - member, and improved methods of referral for services for prevention of - psychological and cardiovascular morbidity during bereavement. -FAU - Zalenski, Robert -AU - Zalenski R -AD - Department of Emergency Medicine, Wayne State University School of Medicine, - Detroit, MI, USA. -FAU - Gillum, Richard F -AU - Gillum RF -FAU - Quest, Tammie E -AU - Quest TE -FAU - Griffith, James L -AU - Griffith JL -LA - eng -PT - Journal Article -PT - Review -DEP - 20060831 -PL - United States -TA - Acad Emerg Med -JT - Academic emergency medicine : official journal of the Society for Academic - Emergency Medicine -JID - 9418450 -SB - IM -MH - *Bereavement -MH - Cardiopulmonary Resuscitation/psychology -MH - *Death, Sudden, Cardiac -MH - Emergency Service, Hospital -MH - Family/*psychology -MH - Humans -MH - *Practice Guidelines as Topic -MH - Stress, Psychological/*etiology -RF - 63 -EDAT- 2006/09/02 09:00 -MHDA- 2006/12/29 09:00 -CRDT- 2006/09/02 09:00 -PHST- 2006/09/02 09:00 [pubmed] -PHST- 2006/12/29 09:00 [medline] -PHST- 2006/09/02 09:00 [entrez] -AID - j.aem.2006.06.029 [pii] -AID - 10.1197/j.aem.2006.06.029 [doi] -PST - ppublish -SO - Acad Emerg Med. 2006 Dec;13(12):1333-8. doi: 10.1197/j.aem.2006.06.029. Epub 2006 - Aug 31. - -PMID- 18942267 -OWN - NLM -STAT- MEDLINE -DCOM- 20081218 -LR - 20171116 -IS - 0016-3813 (Print) -IS - 0016-3813 (Linking) -VI - 144 -IP - 4 -DP - 2008 Jul-Aug -TI - [Cardiovascular risk among adults with obstructive sleep apnea syndrome]. -PG - 323-32 -AB - Cardiovascular diseases and sleep-disordered breathing have been recognized as a - public health problem in Mexico and worldwide. These two groups of disorders are - closely associated and the evidence accumulated over the last 25 years indicates - that obstructive sleep apnea syndrome (OSAS) is an independent risk factor in - systemic arterial hypertension, coronary artery disease and stroke. Other - associations have also been described, linking these disorders with pulmonary - hypertension, cardiac arrhythmias, sudden death during sleep and congestive heart - failure. Treatment with continuous positive airway pressure in patients with OSAS - has proven to be an efficient primary and secondary cardiovascular prevention - strategy. This article reviews the epidemiological evidence that links OSAS with - increased cardiovascular risk, and proposes strategies designed to address this - growing health problem. -FAU - Torre-Bouscoulet, Luis -AU - Torre-Bouscoulet L -AD - Clinica de Sueño, Instituto Nacional de Enfermedades Respiratorias, México DF, - México. -FAU - Meza-Vargas, María Sonia -AU - Meza-Vargas MS -FAU - Castorena-Maldonado, Armando -AU - Castorena-Maldonado A -FAU - Pérez-Padilla, Rogelio -AU - Pérez-Padilla R -LA - spa -PT - Journal Article -PT - Review -TT - Riesgo cardiovascular en adultos con síndrome de apnea obstructiva del sueño. A - 25 años de los primeros estudios de asociación. -PL - Mexico -TA - Gac Med Mex -JT - Gaceta medica de Mexico -JID - 0010333 -SB - IM -MH - Adult -MH - Cardiovascular Diseases/epidemiology/*etiology -MH - Humans -MH - Hypertension/etiology -MH - Metabolic Syndrome/etiology -MH - Risk Factors -MH - Sleep Apnea, Obstructive/*complications -RF - 161 -EDAT- 2008/10/24 09:00 -MHDA- 2008/12/19 09:00 -CRDT- 2008/10/24 09:00 -PHST- 2008/10/24 09:00 [pubmed] -PHST- 2008/12/19 09:00 [medline] -PHST- 2008/10/24 09:00 [entrez] -PST - ppublish -SO - Gac Med Mex. 2008 Jul-Aug;144(4):323-32. - -PMID- 20966309 -OWN - NLM -STAT- MEDLINE -DCOM- 20101202 -LR - 20161125 -IS - 1546-3141 (Electronic) -IS - 0361-803X (Linking) -VI - 195 -IP - 5 -DP - 2010 Nov -TI - Aortic valve and ascending thoracic aorta: Evaluation with isotropic MDCT. -PG - 1072-81 -LID - 10.2214/AJR.09.2668 [doi] -AB - OBJECTIVE: The purpose of this review is to show the range of abnormality - involving the aortic valve and ascending thoracic aorta using 64- and 128-MDCT - with 2D and 3D CT angiography. CONCLUSION: Ascending aorta abnormality can be - complicated by secondary involvement or associated disease involving the aortic - valve, coronary arteries, and heart. Interactive interrogation of high-quality - isotropic volumes, with both 2D and 3D rendering tools, is essential to identify - the full array of findings for best interpretative performance. -FAU - Johnson, Pamela T -AU - Johnson PT -AD - The Russell H. Morgan Department of Radiology and Radiological Science, Johns - Hopkins University School of Medicine, Baltimore, MD 21287, USA. - pjohnso5@jhmi.edu -FAU - Horton, Karen M -AU - Horton KM -FAU - Fishman, Elliot K -AU - Fishman EK -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - AJR Am J Roentgenol -JT - AJR. American journal of roentgenology -JID - 7708173 -SB - IM -MH - Angiography -MH - Aorta, Thoracic/*diagnostic imaging -MH - Aortic Diseases/*diagnostic imaging -MH - Aortic Valve/*diagnostic imaging -MH - Humans -MH - Imaging, Three-Dimensional -MH - Tomography, X-Ray Computed/*methods -EDAT- 2010/10/23 06:00 -MHDA- 2010/12/14 06:00 -CRDT- 2010/10/23 06:00 -PHST- 2010/10/23 06:00 [entrez] -PHST- 2010/10/23 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -AID - 195/5/1072 [pii] -AID - 10.2214/AJR.09.2668 [doi] -PST - ppublish -SO - AJR Am J Roentgenol. 2010 Nov;195(5):1072-81. doi: 10.2214/AJR.09.2668. - -PMID- 28496859 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20201001 -IS - 1941-6911 (Print) -IS - 1941-6911 (Electronic) -IS - 1941-6911 (Linking) -VI - 6 -IP - 1 -DP - 2013 Jun-Jul -TI - Anti-Arrhythmic Agents in the Treatment of Atrial Fibrillation. -PG - 864 -LID - 10.4022/jafib.864 [doi] -LID - 864 -AB - Although atrial fibrillation (AF) is the most common sustained arrhythmia seen - during daily cardiovascular physician practice, its management remained a - challenge for cardiology physician as there was no single anti-arrhythmic agents - proved to be effective in converting atrial fibrillation and kept its - effectiveness in maintaining sinus rhythm over long term. Moreover all the - anti-arrhythmic agents that are used in treatment of AF were potentially - pro-arrhythmic especially in patients with coronary artery disease and - structurally abnormal heart. Some of these drugs also have serious non cardiac - side effects that limit its long term use in the management of atrial - fibrillation. Several new and investigational anti-arrhythmic agents are emerging - but data supporting their effectiveness and safety are still limited. In this - systematic review we examine the efficacy and safety of these medications - supported by the major published randomized trials, meta-analyses and review - articles and conclude with a summary of guidelines recommendations. -FAU - Hassan, Omar F -AU - Hassan OF -AD - Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, - Qatar. -FAU - Al Suwaidi, Jassim -AU - Al Suwaidi J -AD - Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, - Qatar. -FAU - Salam, Amar M -AU - Salam AM -AD - Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, - Qatar. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130630 -PL - United States -TA - J Atr Fibrillation -JT - Journal of atrial fibrillation -JID - 101514767 -PMC - PMC5153068 -OTO - NOTNLM -OT - Atrial fibrillation -OT - anti-arrhythmic agents -OT - conversion -OT - sinus rhythm -OT - treatment -EDAT- 2013/06/30 00:00 -MHDA- 2013/06/30 00:01 -PMCR- 2013/06/30 -CRDT- 2017/05/13 06:00 -PHST- 2013/04/02 00:00 [received] -PHST- 2013/04/28 00:00 [revised] -PHST- 2013/04/29 00:00 [accepted] -PHST- 2017/05/13 06:00 [entrez] -PHST- 2013/06/30 00:00 [pubmed] -PHST- 2013/06/30 00:01 [medline] -PHST- 2013/06/30 00:00 [pmc-release] -AID - 10.4022/jafib.864 [doi] -PST - epublish -SO - J Atr Fibrillation. 2013 Jun 30;6(1):864. doi: 10.4022/jafib.864. eCollection - 2013 Jun-Jul. - -PMID- 17391637 -OWN - NLM -STAT- MEDLINE -DCOM- 20071012 -LR - 20161031 -IS - 0003-4266 (Print) -IS - 0003-4266 (Linking) -VI - 68 -IP - 2-3 -DP - 2007 Jun -TI - [After the LDL receptor and apolipoprotein B, autosomal dominant - hypercholesterolemia reveals its third protagonist: PCSK9]. -PG - 138-46 -AB - The genes encoding the low-density lipoproteins receptor and its ligand - apolipoprotein B, have been the only two genes classically implicated in - autosomal dominant hypercholesterolemia. We have identified in 2003, the third - gene implicated in this disease: PCSK9 (Proprotein Convertase Subtilin Kexin 9). - Several mutations (p.S127R, p.F216L, p.D374Y...) of this gene have been reported - to cause hypercholesterolemia by a gain of function leading to a reduction of LDL - receptor levels. Other variations of PCSK9 are conversely associated with - hypocholesterolemia particularly the non-sense p.Y142X and p.C679X mutations - found in 2% of black Americans and associated with a decrease of LDL levels and - coronary heart diseases. PCSK9 substrates and exact role have not been elucidated - yet, but it seems that PCSK9 is definitely a major actor in cholesterol - homeostasis. PCSK9 inhibitors might constitute new therapeutic targets that would - decrease plasma LDL cholesterol levels and be synergistic with statin drugs. -FAU - Abifadel, M -AU - Abifadel M -AD - Inserm, U781, Paris, France. abifadel@necker.fr -FAU - Rabès, J-P -AU - Rabès JP -FAU - Boileau, C -AU - Boileau C -FAU - Varret, M -AU - Varret M -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Après le récepteur des LDL et l'apolipoprotéine B, l'hypercholestérolémie - familiale révèle son troisième protagoniste: PCSK9. -DEP - 20070327 -PL - France -TA - Ann Endocrinol (Paris) -JT - Annales d'endocrinologie -JID - 0116744 -RN - 0 (Apolipoproteins B) -RN - 0 (Receptors, LDL) -RN - 0 (Transcription Factors) -RN - EC 3.4.21.- (PCSK7 protein, human) -RN - EC 3.4.21.- (Subtilisins) -SB - IM -MH - Animals -MH - Apolipoproteins B/*metabolism -MH - Humans -MH - Hypercholesterolemia/*metabolism -MH - Receptors, LDL/*metabolism -MH - Subtilisins/genetics/*physiology -MH - Transcription Factors/genetics -RF - 41 -EDAT- 2007/03/30 09:00 -MHDA- 2007/10/13 09:00 -CRDT- 2007/03/30 09:00 -PHST- 2006/12/04 00:00 [received] -PHST- 2006/12/27 00:00 [revised] -PHST- 2007/02/01 00:00 [accepted] -PHST- 2007/03/30 09:00 [pubmed] -PHST- 2007/10/13 09:00 [medline] -PHST- 2007/03/30 09:00 [entrez] -AID - S0003-4266(07)00037-6 [pii] -AID - 10.1016/j.ando.2007.02.002 [doi] -PST - ppublish -SO - Ann Endocrinol (Paris). 2007 Jun;68(2-3):138-46. doi: 10.1016/j.ando.2007.02.002. - Epub 2007 Mar 27. - -PMID- 21544535 -OWN - NLM -STAT- MEDLINE -DCOM- 20121207 -LR - 20211020 -IS - 1970-9366 (Electronic) -IS - 1828-0447 (Linking) -VI - 7 -IP - 4 -DP - 2012 Aug -TI - The role of statins in stroke. -PG - 305-11 -LID - 10.1007/s11739-011-0603-x [doi] -AB - Although evidence from epidemiological studies examining a relationship between - cholesterol level and stroke is less than definitive, there is a compelling - evidence from the clinical therapy trials primarily designed to examine the - coronary benefits of statins that statin therapy also causes a reduction in the - risk of stroke. Even though a stroke does not have the same exact pathophysiology - as a heart attack, specific trials in stroke patients confirm advantages and - risks of statin therapy in this kind of population. In primary prevention, - statins are effective both when low-density lipoprotein (LDL) is raised and when - hs-CRP is elevated. In secondary prevention, an absolute reduction of recurrent - stroke can be obtained with statins, with a number needed to treat at 5 years of - 45. -FAU - Paliani, Ugo -AU - Paliani U -AD - Division of Internal Medicine, ASL 1 Umbria, via Engels-Voc.Chioccolo, 06012 - Città di Castello (Perugia), Italy. ugo.paliani@ASLasl1.umbria.it -FAU - Ricci, Stefano -AU - Ricci S -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -DEP - 20110505 -PL - Italy -TA - Intern Emerg Med -JT - Internal and emergency medicine -JID - 101263418 -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Triglycerides) -RN - 9007-41-4 (C-Reactive Protein) -SB - IM -CIN - Intern Emerg Med. 2012 Sep;7 Suppl 2:S89-90. doi: 10.1007/s11739-011-0652-1. - PMID: 21713546 -MH - Acute Disease -MH - Brain Ischemia/*prevention & control -MH - C-Reactive Protein -MH - Cholesterol, LDL/drug effects -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Primary Prevention -MH - Risk Assessment -MH - Secondary Prevention -MH - Stroke/*prevention & control -MH - Triglycerides -EDAT- 2011/05/06 06:00 -MHDA- 2012/12/12 06:00 -CRDT- 2011/05/06 06:00 -PHST- 2010/10/29 00:00 [received] -PHST- 2011/04/19 00:00 [accepted] -PHST- 2011/05/06 06:00 [entrez] -PHST- 2011/05/06 06:00 [pubmed] -PHST- 2012/12/12 06:00 [medline] -AID - 10.1007/s11739-011-0603-x [doi] -PST - ppublish -SO - Intern Emerg Med. 2012 Aug;7(4):305-11. doi: 10.1007/s11739-011-0603-x. Epub 2011 - May 5. - -PMID- 17704643 -OWN - NLM -STAT- MEDLINE -DCOM- 20071113 -LR - 20200930 -IS - 1551-4005 (Electronic) -IS - 1551-4005 (Linking) -VI - 6 -IP - 20 -DP - 2007 Oct 15 -TI - Coregulators in adipogenesis: what could we learn from the SRC (p160) coactivator - family? -PG - 2448-52 -AB - Strong epidemiological studies clearly show that reduction in body fat content - decreases the risk for many clinical conditions including diabetes, hypertension, - coronary atherosclerotic heart disease and some forms of cancer. Therefore, - detailed understanding of the mechanisms underlying how fat pads expand appears - crucial. Extensive studies already identified a cohort of transcription factors - involved in adipocyte differentiation but the fine interrelationship between the - myriads of cellular and molecular events occurring during this complex biological - process is far from being completely understood. Since the cloning of the first - coregulator, the impact of those molecules has dramatically increased. In this - review, we will summarize the emerging impact of coregulators on energy balance - with a specific interest for fat formation. Emphasis will be given to the - coactivators of the SRC (p160) family. -FAU - Louet, Jean-Francois -AU - Louet JF -AD - Department of Molecular and Cellular Biology, Baylor College of Medicine, - Houston, Texas 77030, USA. -FAU - O'Malley, Bert W -AU - O'Malley BW -LA - eng -GR - DK59820/DK/NIDDK NIH HHS/United States -GR - U19DKO62434/PHS HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20070722 -PL - United States -TA - Cell Cycle -JT - Cell cycle (Georgetown, Tex.) -JID - 101137841 -RN - EC 2.7.10.2 (src-Family Kinases) -SB - IM -MH - Adipocytes/cytology/metabolism -MH - *Adipogenesis -MH - Animals -MH - Humans -MH - Signal Transduction -MH - src-Family Kinases/*classification/*metabolism -RF - 51 -EDAT- 2007/08/21 09:00 -MHDA- 2007/11/14 09:00 -CRDT- 2007/08/21 09:00 -PHST- 2007/08/21 09:00 [pubmed] -PHST- 2007/11/14 09:00 [medline] -PHST- 2007/08/21 09:00 [entrez] -AID - 4777 [pii] -AID - 10.4161/cc.6.20.4777 [doi] -PST - ppublish -SO - Cell Cycle. 2007 Oct 15;6(20):2448-52. doi: 10.4161/cc.6.20.4777. Epub 2007 Jul - 22. - -PMID- 23803294 -OWN - NLM -STAT- MEDLINE -DCOM- 20140204 -LR - 20220410 -IS - 1347-4820 (Electronic) -IS - 1346-9843 (Linking) -VI - 77 -IP - 7 -DP - 2013 -TI - Cardiovascular disease epidemiology in Asia: an overview. -PG - 1646-52 -AB - Cardiovascular disease (CVD) is the leading cause of death in the world and half - of the cases of CVD are estimated to occur in Asia. Compared with Western - countries, most Asian countries, except for Japan, South Korea, Singapore and - Thailand, have higher age-adjusted mortality from CVD. In Japan, the mortality - from CVD, especially stroke, has declined continuously from the 1960s to the - 2000s, which has contributed to making Japan into the top-ranking country for - longevity in the world. Hypertension and smoking are the most notable risk - factors for stroke and coronary artery disease, whereas dyslipidemia and diabetes - mellitus are risk factors for ischemic heart disease and ischemic stroke. The - nationwide approach to hypertension prevention and control has contributed to a - substantial decline in stroke mortality in Japan. Recent antismoking campaigns - have contributed to a decline in the smoking rate among men. Conversely, the - prevalence of dyslipidemia and diabetes mellitus increased from the 1980s to the - 2000s and, therefore, the population-attributable risks of CVD for dyslipidemia - and diabetes mellitus have increased moderately. To prevent future CVD in Asia, - the intensive prevention programs for hypertension and smoking should be - continued and that for emerging metabolic risk factors should be intensified in - Japan. The successful intervention programs in Japan can be applied to other - Asian countries. -FAU - Ohira, Tetsuya -AU - Ohira T -AD - Department of Epidemiology, Radiation Medical Center for the Fukushima Health - Management Survey, Fukushima Medical University, Fukushima, Japan. -FAU - Iso, Hiroyasu -AU - Iso H -LA - eng -PT - Journal Article -PT - Review -DEP - 20130621 -PL - Japan -TA - Circ J -JT - Circulation journal : official journal of the Japanese Circulation Society -JID - 101137683 -SB - IM -MH - Asia/epidemiology -MH - Cardiovascular Diseases/etiology/*mortality/*prevention & control -MH - Diabetes Complications/mortality/prevention & control -MH - Diabetes Mellitus/mortality/prevention & control -MH - Dyslipidemias/complications/mortality/prevention & control -MH - Female -MH - Humans -MH - Male -MH - Prevalence -MH - Risk Factors -MH - Smoking/adverse effects/mortality -MH - Smoking Prevention -EDAT- 2013/06/28 06:00 -MHDA- 2014/02/05 06:00 -CRDT- 2013/06/28 06:00 -PHST- 2013/06/28 06:00 [entrez] -PHST- 2013/06/28 06:00 [pubmed] -PHST- 2014/02/05 06:00 [medline] -AID - DN/JST.JSTAGE/circj/CJ-13-0702 [pii] -AID - 10.1253/circj.cj-13-0702 [doi] -PST - ppublish -SO - Circ J. 2013;77(7):1646-52. doi: 10.1253/circj.cj-13-0702. Epub 2013 Jun 21. - -PMID- 21557734 -OWN - NLM -STAT- MEDLINE -DCOM- 20120508 -LR - 20240406 -IS - 1476-5381 (Electronic) -IS - 0007-1188 (Print) -IS - 0007-1188 (Linking) -VI - 165 -IP - 3 -DP - 2012 Feb -TI - Obesity and risk of vascular disease: importance of endothelium-dependent - vasoconstriction. -PG - 591-602 -LID - 10.1111/j.1476-5381.2011.01472.x [doi] -AB - Obesity has become a serious global health issue affecting both adults and - children. Recent devolopments in world demographics and declining health status - of the world's population indicate that the prevalence of obesity will continue - to increase in the next decades. As a disease, obesity has deleterious effects on - metabolic homeostasis, and affects numerous organ systems including heart, kidney - and the vascular system. Thus, obesity is now regarded as an independent risk - factor for atherosclerosis-related diseases such as coronary artery disease, - myocardial infarction and stroke. In the arterial system, endothelial cells are - both the source and target of factors contributing to atherosclerosis. - Endothelial vasoactive factors regulate vascular homeostasis under physiological - conditions and maintain basal vascular tone. Obesity results in an imbalance - between endothelium-derived vasoactive factors favouring vasoconstriction, cell - growth and inflammatory activation. Abnormal regulation of these factors due to - endothelial cell dysfunction is both a consequence and a cause of vascular - disease processes. Finally, because of the similarities of the vascular - pathomechanisms activated, obesity can be considered to cause accelerated, - 'premature' vascular aging. Here, we will review some of the pathomechanisms - involved in obesity-related activation of endothelium-dependent vasoconstriction, - the clinical relevance of obesity-associated vascular risk, and therapeutic - interventions using 'endothelial therapy' aiming at maintaining or restoring - vascular endothelial health. LINKED ARTICLES: This article is part of a themed - section on Fat and Vascular Responsiveness. To view the other articles in this - section visit http://dx.doi.org/10.1111/bph.2012.165.issue-3. -CI - © 2011 The Authors. British Journal of Pharmacology © 2011 The British - Pharmacological Society. -FAU - Barton, Matthias -AU - Barton M -AD - Molecular Internal Medicine, University of Zurich, Zurich, Switzerland. - barton@access.uzh.ch -FAU - Baretella, Oliver -AU - Baretella O -FAU - Meyer, Matthias R -AU - Meyer MR -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Br J Pharmacol -JT - British journal of pharmacology -JID - 7502536 -SB - IM -MH - Animals -MH - Endothelium, Vascular/*physiopathology -MH - Humans -MH - Obesity/*physiopathology -MH - Risk -MH - Vascular Diseases/*physiopathology -MH - Vasoconstriction -PMC - PMC3315033 -EDAT- 2011/05/12 06:00 -MHDA- 2012/05/09 06:00 -PMCR- 2013/02/01 -CRDT- 2011/05/12 06:00 -PHST- 2011/05/12 06:00 [entrez] -PHST- 2011/05/12 06:00 [pubmed] -PHST- 2012/05/09 06:00 [medline] -PHST- 2013/02/01 00:00 [pmc-release] -AID - 10.1111/j.1476-5381.2011.01472.x [doi] -PST - ppublish -SO - Br J Pharmacol. 2012 Feb;165(3):591-602. doi: 10.1111/j.1476-5381.2011.01472.x. - -PMID- 17666197 -OWN - NLM -STAT- MEDLINE -DCOM- 20070925 -LR - 20080410 -IS - 0002-9149 (Print) -IS - 0002-9149 (Linking) -VI - 100 -IP - 3A -DP - 2007 Aug 6 -TI - Angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors: - where do we stand now? -PG - 38J-44J -AB - Cardiovascular disease represents a continuum that starts with risk factors, such - as hypertension, and progresses to atherosclerosis, target organ damage, and - ultimately leads to heart failure or stroke. Renin-angiotensin-aldosterone system - (RAAS) blockade with angiotensin-converting enzyme (ACE) inhibitors or - angiotensin receptor blockers (ARBs) has been shown to be beneficial at all - stages of this continuum. Both classes of agent can prevent or reverse - endothelial dysfunction and atherosclerosis, thereby potentially reducing the - risk of cardiovascular events. Such a reduction has been shown with ACE - inhibitors in patients with coronary artery disease, but no such data are - currently available for ARBs. Both ACE inhibitors and ARBs have been shown to - reduce damage in target organs, such as the heart and kidney, and to decrease - cardiovascular mortality and morbidity in patients with congestive heart failure. - Trials, such as the Ongoing Telmisartan Alone in Combination with Ramipril Global - Endpoint Trial (ONTARGET) and the Telmisartan Randomised Assessment Study in - ACE-Intolerant Subjects with Cardiovascular Disease (TRANSCEND), that compare - telmisartan, ramipril, and their combination in high-risk patients with vascular - end-organ damage, should provide important new insights into the benefits of - intervention with RAS blockade along the cardiorenovascular continuum. -FAU - Böhm, Michael -AU - Böhm M -AD - Department of Internal Medicine III, Cardiology/Angiology and Intensive Cardiac - Medicine, University of Saarland, Homburg/Saar, Germany. - michael.boehm@uniklinikum-saarland.de -LA - eng -PT - Journal Article -PT - Review -DEP - 20070525 -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -CIN - Am J Cardiol. 2008 Mar 1;101(5):744-5. doi: 10.1016/j.amjcard.2007.10.013. PMID: - 18308033 -MH - Angiotensin II Type 1 Receptor Blockers/administration & dosage/*therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/administration & dosage/*therapeutic use -MH - Cardiovascular Diseases/physiopathology/*prevention & control -MH - Drug Therapy, Combination -MH - Humans -MH - Randomized Controlled Trials as Topic -MH - Renin-Angiotensin System/drug effects -RF - 55 -EDAT- 2007/09/12 09:00 -MHDA- 2007/09/26 09:00 -CRDT- 2007/09/12 09:00 -PHST- 2007/09/12 09:00 [pubmed] -PHST- 2007/09/26 09:00 [medline] -PHST- 2007/09/12 09:00 [entrez] -AID - S0002-9149(07)00976-9 [pii] -AID - 10.1016/j.amjcard.2007.05.013 [doi] -PST - ppublish -SO - Am J Cardiol. 2007 Aug 6;100(3A):38J-44J. doi: 10.1016/j.amjcard.2007.05.013. - Epub 2007 May 25. - -PMID- 22389121 -OWN - NLM -STAT- MEDLINE -DCOM- 20120712 -LR - 20211021 -IS - 1932-8737 (Electronic) -IS - 0160-9289 (Print) -IS - 0160-9289 (Linking) -VI - 35 -IP - 3 -DP - 2012 Mar -TI - Arrhythmias in women. -PG - 166-71 -LID - 10.1002/clc.21975 [doi] -AB - There are important gender differences in cardiac electrophysiology that affect - the epidemiology, presentation, and prognosis of various arrhythmias. Women have - been noted to have higher resting heart rates compared to men. They also have a - longer QT interval, which puts them at an increased risk for drug-induced - torsades de pointes. Women with atrial fibrillation are at a higher risk of - stroke, and they are less likely to receive anticoagulation and ablation - procedures compared to men. Women have a lower risk of sudden cardiac death and - are less likely to have known coronary artery disease at the time of an event - compared to men. Both men and women have been shown to derive an equal survival - benefit from implantable cardioverter defibrillators and cardiac - resynchronization therapy, although these devices are significantly underutilized - in women. Women also appear to have a better response to cardiac - resynchronization therapy in terms of reduced numbers of hospitalizations and - more robust reverse ventricular remodeling. Further studies are required to - elucidate the underlying pathophysiology of these sex differences in cardiac - arrhythmias. -CI - © 2012 Wiley Periodicals, Inc. -FAU - Curtis, Anne B -AU - Curtis AB -AD - Department of Medicine, University at Buffalo, Buffalo, New York 14203, USA. - abcurtis@buffalo.edu -FAU - Narasimha, Deepika -AU - Narasimha D -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Cardiol -JT - Clinical cardiology -JID - 7903272 -SB - IM -MH - *Arrhythmias, Cardiac/epidemiology/physiopathology/therapy -MH - Female -MH - Humans -MH - Male -MH - Prevalence -MH - Sex Factors -MH - *Women's Health -PMC - PMC6652373 -EDAT- 2012/03/06 06:00 -MHDA- 2012/07/13 06:00 -PMCR- 2012/03/02 -CRDT- 2012/03/06 06:00 -PHST- 2012/03/06 06:00 [entrez] -PHST- 2012/03/06 06:00 [pubmed] -PHST- 2012/07/13 06:00 [medline] -PHST- 2012/03/02 00:00 [pmc-release] -AID - CLC21975 [pii] -AID - 10.1002/clc.21975 [doi] -PST - ppublish -SO - Clin Cardiol. 2012 Mar;35(3):166-71. doi: 10.1002/clc.21975. - -PMID- 16778758 -OWN - NLM -STAT- MEDLINE -DCOM- 20061012 -LR - 20060616 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 54 -IP - 2 -DP - 2006 Apr -TI - The inflammatory abdominal aortic aneurysm and coronary artery disease. Case - report and review. -PG - 265-71 -AB - Inflammatory abdominal aortic aneurysm (IAAA) is defined as an unusually - thickened aneurysmatic wall, encircled by a wide dense perianeurysmal and/or - retroperitoneal fibrosis with adjacent tissues adhesion, and is now considered as - an extreme shape of the common phlogistic process involved in atherosclerotic - plaque formation. Latest studies demonstrated that inflammation plays an - important role in coronary disease and in other atherosclerosis manifestations. - We introduce the clinical case of a patient with IAAA who developed an acute - myocardial infarction 6 months after the surgical procedure on the aorta. Through - a literature review about IAAA we stress the clinical usefulness of the - inflammatory markers as independent predictors in management of patients with - coronary disease and we present the hypothesis, related to the introduced case, - of an advanced coronary disease, aggravated or clinically revealed after the - cytokine storm related to important localized inflammatory engagements or great - vascular surgery treatments. -FAU - Monte, I -AU - Monte I -AD - Department of Internal Medicine and Specialistic Medicine, University of Catania, - Catania, Italy. inemonte@unict.it -FAU - Capodanno, D -AU - Capodanno D -FAU - Licciardi, S -AU - Licciardi S -FAU - Ferraro, C -AU - Ferraro C -FAU - Giannone, M T -AU - Giannone MT -FAU - Grasso, S -AU - Grasso S -FAU - Nicolosi, E -AU - Nicolosi E -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -SB - IM -MH - Aortic Aneurysm, Abdominal/*complications/diagnosis -MH - Aortitis/*complications/diagnosis -MH - Humans -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/*etiology -RF - 24 -EDAT- 2006/06/17 09:00 -MHDA- 2006/10/13 09:00 -CRDT- 2006/06/17 09:00 -PHST- 2006/06/17 09:00 [pubmed] -PHST- 2006/10/13 09:00 [medline] -PHST- 2006/06/17 09:00 [entrez] -PST - ppublish -SO - Minerva Cardioangiol. 2006 Apr;54(2):265-71. - -PMID- 24291270 -OWN - NLM -STAT- MEDLINE -DCOM- 20140415 -LR - 20211021 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Print) -IS - 0735-1097 (Linking) -VI - 63 -IP - 5 -DP - 2014 Feb 11 -TI - Pre-clinical diastolic dysfunction. -PG - 407-16 -LID - S0735-1097(13)06160-3 [pii] -LID - 10.1016/j.jacc.2013.10.063 [doi] -AB - Pre-clinical diastolic dysfunction (PDD) has been broadly defined as left - ventricular diastolic dysfunction without the diagnosis of congestive heart - failure (HF) and with normal systolic function. PDD is an entity that remains - poorly understood, yet has definite clinical significance. Although few original - studies have focused on PDD, it has been shown that PDD is prevalent, and that - there is a clear progression from PDD to symptomatic HF including dyspnea, edema, - and fatigue. In diabetic patients and in patients with coronary artery disease or - hypertension, it has been shown that patients with PDD have a significantly - higher risk of progression to heart failure and death compared with patients - without PDD. Because of these findings and the increasing prevalence of the heart - failure epidemic, it is clear that an understanding of PDD is essential to - decreasing patients' morbidity and mortality. This review will focus on what is - known concerning pre-clinical diastolic dysfunction, including definitions, - staging, epidemiology, pathophysiology, and the natural history of the disease. - In addition, given the paucity of trials focused on PDD treatment, studies - targeting risk factors associated with the development of PDD and therapeutic - trials for heart failure with preserved ejection fraction will be reviewed. -CI - Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Wan, Siu-Hin -AU - Wan SH -AD - Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, - Minnesota. -FAU - Vogel, Mark W -AU - Vogel MW -AD - Division of Cardiovascular Diseases, Washington University, St. Louis, Missouri. -FAU - Chen, Horng H -AU - Chen HH -AD - Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, - Minnesota. Electronic address: chen.horng@mayo.edu. -LA - eng -GR - P01 HL076611/HL/NHLBI NIH HHS/United States -GR - R01 HL084155/HL/NHLBI NIH HHS/United States -GR - R01 HL-84155/HL/NHLBI NIH HHS/United States -GR - P01 HL 76611/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131127 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -CIN - J Am Coll Cardiol. 2014 Aug 5;64(5):529-30. doi: 10.1016/j.jacc.2014.03.054. - PMID: 25082592 -CIN - J Am Coll Cardiol. 2014 Aug 5;64(5):530. doi: 10.1016/j.jacc.2014.04.055. PMID: - 25082593 -MH - Diastole -MH - Disease Progression -MH - Echocardiography -MH - Global Health -MH - Heart Failure/epidemiology/*etiology/physiopathology -MH - Heart Ventricles/diagnostic imaging/*physiopathology -MH - Humans -MH - Prevalence -MH - Prognosis -MH - Risk Factors -MH - *Stroke Volume -MH - *Ventricular Dysfunction, Left/complications/epidemiology/physiopathology -PMC - PMC3934927 -MID - NIHMS542096 -OTO - NOTNLM -OT - B-type natriuretic peptide -OT - BNP -OT - COPD -OT - DD -OT - EF -OT - HF -OT - HFpEF -OT - HFrEF -OT - LV -OT - LVH -OT - N-terminal pro–B-type natriuretic peptide -OT - NT-proBNP -OT - PDD -OT - SD -OT - chronic obstructive pulmonary disease -OT - diastolic dysfunction -OT - echocardiography -OT - ejection fraction -OT - heart failure -OT - heart failure epidemiology -OT - heart failure treatment -OT - heart failure with preserved ejection fraction -OT - heart failure with reduced ejection fraction -OT - left ventricular -OT - left ventricular hypertrophy -OT - pre-clinical diastolic dysfunction -OT - systolic dysfunction -COIS- No conflict of interest or financial disclosures -EDAT- 2013/12/03 06:00 -MHDA- 2014/04/16 06:00 -PMCR- 2015/02/11 -CRDT- 2013/12/03 06:00 -PHST- 2013/03/15 00:00 [received] -PHST- 2013/10/08 00:00 [revised] -PHST- 2013/10/15 00:00 [accepted] -PHST- 2013/12/03 06:00 [entrez] -PHST- 2013/12/03 06:00 [pubmed] -PHST- 2014/04/16 06:00 [medline] -PHST- 2015/02/11 00:00 [pmc-release] -AID - S0735-1097(13)06160-3 [pii] -AID - 10.1016/j.jacc.2013.10.063 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2014 Feb 11;63(5):407-16. doi: 10.1016/j.jacc.2013.10.063. - Epub 2013 Nov 27. - -PMID- 23070276 -OWN - NLM -STAT- MEDLINE -DCOM- 20131113 -LR - 20231213 -IS - 1432-198X (Electronic) -IS - 0931-041X (Linking) -VI - 28 -IP - 6 -DP - 2013 Jun -TI - Cardiovascular risk assessment in children with chronic kidney disease. -PG - 875-84 -LID - 10.1007/s00467-012-2325-3 [doi] -AB - Chronic kidney disease (CKD) is a major factor contributing to cardiovascular - (CV) morbidity and mortality with the highest risk in patients on dialysis. An - estimation of CV risk is important not only to identify potential modifiable risk - factors but also to evaluate the effect of treatments aimed to reduce the risk. - Non-invasive methods of measuring vascular changes and circulating biomarkers are - available to assess the presence and severity of cardiovascular damage. These - include measures of structural (carotid intima-media thickness and coronary - artery calcification score) and functional (aortic pulse wave velocity, 24-h - ambulatory blood pressure monitoring, ambulatory arterial stiffness index, heart - rate variability and flow-mediated dilatation) changes in the vessel wall. In - addition, a number of circulating biomarkers of vascular damage and its - progression have been studied. Many of these tests are well validated as - surrogate markers of future cardiovascular events and death in adult CKD - patients, but need technical adaptation, standardization and validation for use - in children. With our current state of knowledge, these are best reserved for - research studies and scarce clinical resources may be better utilized for - preventative strategies to reduce the modifiable risk factors for calcification - from early CKD stages. -FAU - Shroff, Rukshana -AU - Shroff R -AD - Renal Unit, Great Ormond Street Hospital for Children, London, UK. -FAU - Dégi, Arianna -AU - Dégi A -FAU - Kerti, Andrea -AU - Kerti A -FAU - Kis, Eva -AU - Kis E -FAU - Cseprekál, Orsolya -AU - Cseprekál O -FAU - Tory, Kálmán -AU - Tory K -FAU - Szabó, Attila J -AU - Szabó AJ -FAU - Reusz, George S -AU - Reusz GS -LA - eng -GR - British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121016 -PL - Germany -TA - Pediatr Nephrol -JT - Pediatric nephrology (Berlin, Germany) -JID - 8708728 -RN - 0 (Calcium-Binding Proteins) -RN - 0 (Extracellular Matrix Proteins) -SB - IM -MH - Adolescent -MH - Blood Pressure Monitoring, Ambulatory -MH - Calcium-Binding Proteins/physiology -MH - Cardiovascular Diseases/*etiology -MH - Carotid Intima-Media Thickness -MH - Child -MH - Elasticity -MH - Extracellular Matrix Proteins/physiology -MH - Heart Rate -MH - Humans -MH - Pulse Wave Analysis -MH - Renal Insufficiency, Chronic/*complications -MH - *Risk Assessment -MH - Vascular Calcification/etiology -MH - Vascular Stiffness -MH - Vasodilation -MH - Matrix Gla Protein -EDAT- 2012/10/17 06:00 -MHDA- 2013/11/14 06:00 -CRDT- 2012/10/17 06:00 -PHST- 2012/07/03 00:00 [received] -PHST- 2012/09/14 00:00 [accepted] -PHST- 2012/09/14 00:00 [revised] -PHST- 2012/10/17 06:00 [entrez] -PHST- 2012/10/17 06:00 [pubmed] -PHST- 2013/11/14 06:00 [medline] -AID - 10.1007/s00467-012-2325-3 [doi] -PST - ppublish -SO - Pediatr Nephrol. 2013 Jun;28(6):875-84. doi: 10.1007/s00467-012-2325-3. Epub 2012 - Oct 16. - -PMID- 21983313 -OWN - NLM -STAT- MEDLINE -DCOM- 20120208 -LR - 20131121 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 19 -IP - 6 -DP - 2011 Nov-Dec -TI - Allopurinol as a cardiovascular drug. -PG - 265-71 -LID - 10.1097/CRD.0b013e318229a908 [doi] -AB - Cardiovascular disease (CVD) remains the leading cause of death in the United - States. There is evidence that shows a direct relationship between an elevated - uric acid level and an increased risk of cardiovascular (CV) events, which has - set the foundation for the investigation of uric acid-lowering drugs for the - treatment of CVD. Although traditionally the cornerstone therapy for gout, - allopurinol's ability to be a competitive inhibitor of the key enzyme, xanthine - oxidase, needed for uric acid formation, has prompted recent clinical research - evaluating allopurinol as a CV drug. Epidemiologic and biochemical studies on - uric acid formation have shown that it is not only uric acid itself that leads to - worsening prognosis and increased CV events, but also the free radicals and - superoxides formed during xanthine oxidase activity. The combination of uric acid - formation and formed free radicals could ultimately lead to coronary endothelial - dysfunction and worsening of myocardial oxidative stress. Along with preventing - uric acid formation, allopurinol also has the ability to behave as a free radical - scavenger of the superoxide anions and free radicals released during uric acid - formation.Clinical studies have shown that allopurinol improves endothelial - dysfunction and subsequently improves the exercise capacity in patients diagnosed - with angina pectoris. Allopurinol has also been shown to decrease oxidative - stress and ameliorate the morbidity and mortality of congestive heart failure - patients by possibly improving mechanoenergetic uncoupling, with the enhancement - of myocardial contractility and the left ventricular ejection fraction. This - review presents the pharmacologic action of allopurinol on the CV system and - describes the effectiveness of allopurinol as a potential drug to treat 2 CVD - morbidities: ischemic heart disease and congestive heart failure. -FAU - Kelkar, Anita -AU - Kelkar A -AD - Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA. -FAU - Kuo, Allen -AU - Kuo A -FAU - Frishman, William H -AU - Frishman WH -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Free Radical Scavengers) -RN - 268B43MJ25 (Uric Acid) -RN - 63CZ7GJN5I (Allopurinol) -RN - EC 1.17.3.2 (Xanthine Oxidase) -SB - IM -MH - Allopurinol/*therapeutic use -MH - Cardiovascular Diseases/*drug therapy/enzymology -MH - Free Radical Scavengers/*therapeutic use -MH - Humans -MH - Uric Acid/metabolism -MH - Xanthine Oxidase/metabolism -EDAT- 2011/10/11 06:00 -MHDA- 2012/02/09 06:00 -CRDT- 2011/10/11 06:00 -PHST- 2011/10/11 06:00 [entrez] -PHST- 2011/10/11 06:00 [pubmed] -PHST- 2012/02/09 06:00 [medline] -AID - 00045415-201111000-00001 [pii] -AID - 10.1097/CRD.0b013e318229a908 [doi] -PST - ppublish -SO - Cardiol Rev. 2011 Nov-Dec;19(6):265-71. doi: 10.1097/CRD.0b013e318229a908. - -PMID- 18536779 -OWN - NLM -STAT- MEDLINE -DCOM- 20080630 -LR - 20220310 -IS - 1699-3993 (Print) -IS - 1699-3993 (Linking) -VI - 44 -IP - 3 -DP - 2008 Mar -TI - Ivabradine: I(f) inhibition in the management of stable angina pectoris and other - cardiovascular diseases. -PG - 171-81 -LID - 10.1358/dot.2008.44.1193864 [doi] -AB - Elevated heart rate plays a major role in coronary artery disease, not only as a - trigger of most ischemic episodes but also as a significant predictor of - cardiovascular morbidity and mortality. Heart rate is an important target in the - management of stable angina pectoris. Against this background, a new class of - antianginal drugs has recently become available: the selective and specific I(f) - inhibitors. The mode of action of this novel class involves selective and - specific inhibition of the major pacemaker current in the sinoatrial node, the - mixed sodium/potassium current (I(f)), which results in pure heart rate - reduction. The first member of this class available for clinical use is - ivabradine (available under the brandnames of Procoralan, Coralan, Corlentor, - Coraxan, Servier, France). Building on solid preclinical studies, ivabradine was - shown to have anti-ischemic and antianginal efficacy in patients with stable - angina pectoris in clinical trials versus placebo, beta-blockers and calcium - channel blockers. Ongoing studies will determine the potential of pure heart rate - reduction with ivabradine to improve morbidity and mortality. -FAU - Tardif, Jean-Claude -AU - Tardif JC -AD - Montreal Heart Institute, University of Montreal, Montreal, QC, Canada. - jean-claude.tardif@icm-mhi.org -LA - eng -PT - Journal Article -PT - Review -PL - Spain -TA - Drugs Today (Barc) -JT - Drugs of today (Barcelona, Spain : 1998) -JID - 101160518 -RN - 0 (Benzazepines) -RN - 0 (Cardiotonic Agents) -RN - 3H48L0LPZQ (Ivabradine) -SB - IM -MH - Angina Pectoris/*drug therapy/physiopathology -MH - Animals -MH - Benzazepines/adverse effects/chemistry/pharmacokinetics/pharmacology/*therapeutic - use -MH - Cardiotonic Agents/adverse - effects/chemistry/pharmacokinetics/pharmacology/*therapeutic use -MH - Cardiovascular Diseases/*drug therapy/physiopathology -MH - Heart Rate/*drug effects -MH - Humans -MH - Ivabradine -RF - 42 -EDAT- 2008/06/10 09:00 -MHDA- 2008/07/01 09:00 -CRDT- 2008/06/10 09:00 -PHST- 2008/06/10 09:00 [pubmed] -PHST- 2008/07/01 09:00 [medline] -PHST- 2008/06/10 09:00 [entrez] -AID - 1193864 [pii] -AID - 10.1358/dot.2008.44.1193864 [doi] -PST - ppublish -SO - Drugs Today (Barc). 2008 Mar;44(3):171-81. doi: 10.1358/dot.2008.44.1193864. - -PMID- 20181524 -OWN - NLM -STAT- MEDLINE -DCOM- 20110602 -LR - 20250529 -IS - 1444-2892 (Electronic) -IS - 1443-9506 (Linking) -VI - 19 -IP - 3 -DP - 2010 Mar -TI - Congenital heart disease and multi-modality imaging. -PG - 133-44 -LID - 10.1016/j.hlc.2010.01.001 [doi] -AB - The increasing prevalence of adult congenital heart disease (CHD) can be - attributed to major improvements in diagnosis and treatment of children with CHD. - Although, echocardiography is the most commonly used imaging modality for - diagnosis and follow up of subjects with CHD, the evolution of both - cardiovascular magnetic resonance (MR) imaging and computed tomography (CT) does - offer new ways to visualise the heart and great vessels. Cardiovascular MR - techniques such as spin-echo and gradient-echo imaging, velocity-encoded - phase-contrast MR and gadolinium-enhanced MR angiography allow comprehensive - assessment of cardiac anatomy and function. This provides information about the - long-term sequelae of the underlying anatomy, haemodynamic assessment of residual - post-operative lesions and complications of surgery. Similarly, the development - of spiral and subsequently multi-detector CT enables the acquisition of data - during a single breath-hold and during the first pass of a contrast bolus, so - that images can be reconstructed in any two-dimensional plane or in - three-dimensions. As much of the functional data in CHD patients was - traditionally acquired with invasive X-ray angiography, non-invasive alternatives - such as cardiovascular MR and CT are desirable. This review evaluates the role of - imaging modalities in the management of subjects with CHD, particularly detailing - recent developments in imaging techniques as they relate to the various CHD - diagnoses commonly encountered in practice. -FAU - Puranik, Rajesh -AU - Puranik R -AD - Cardiovascular Magnetic Resonance Unit, Great Ormond St Hospital, UK. - rpuranik@mail.usyd.edu.au -FAU - Muthurangu, Vivek -AU - Muthurangu V -FAU - Celermajer, David S -AU - Celermajer DS -FAU - Taylor, Andrew M -AU - Taylor AM -LA - eng -GR - FS/08/012/24454/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100223 -PL - Australia -TA - Heart Lung Circ -JT - Heart, lung & circulation -JID - 100963739 -RN - AU0V1LM3JT (Gadolinium) -SB - IM -MH - Australia/epidemiology -MH - *Coronary Vessels -MH - Gadolinium -MH - Heart Defects, Congenital/*diagnosis/diagnostic imaging/epidemiology -MH - Hemodynamics -MH - Humans -MH - Magnetic Resonance Imaging, Cine -MH - Pulmonary Atresia/diagnosis -MH - Tetralogy of Fallot/diagnosis -MH - Tomography, X-Ray Computed/instrumentation -MH - Transposition of Great Vessels/diagnosis -MH - Ultrasonography -RF - 59 -EDAT- 2010/02/26 06:00 -MHDA- 2011/06/03 06:00 -CRDT- 2010/02/26 06:00 -PHST- 2009/05/20 00:00 [received] -PHST- 2009/12/09 00:00 [revised] -PHST- 2010/01/04 00:00 [accepted] -PHST- 2010/02/26 06:00 [entrez] -PHST- 2010/02/26 06:00 [pubmed] -PHST- 2011/06/03 06:00 [medline] -AID - S1443-9506(10)00003-X [pii] -AID - 10.1016/j.hlc.2010.01.001 [doi] -PST - ppublish -SO - Heart Lung Circ. 2010 Mar;19(3):133-44. doi: 10.1016/j.hlc.2010.01.001. Epub 2010 - Feb 23. - -PMID- 22748194 -OWN - NLM -STAT- MEDLINE -DCOM- 20130108 -LR - 20151119 -IS - 1525-139X (Electronic) -IS - 0894-0959 (Linking) -VI - 25 -IP - 4 -DP - 2012 Jul -TI - The diagnostic utility of cardiac biomarkers in dialysis patients. -PG - 388-96 -LID - 10.1111/j.1525-139X.2012.01099.x [doi] -AB - Mortality in dialysis patients remains high due to excessive cardiovascular - disease burden from coronary artery disease, left ventricular hypertrophy, and - heart failure. Thus, cardiovascular risk stratification is an important aspect in - managing dialysis patients; it may enable early identification of high-risk - patients to optimize therapeutic interventions that may ultimately lower their - cardiovascular morbidity and mortality. In particular, serum cardiac biomarkers - that are readily measured, inexpensive, reproducible with high sensitivity and - specificity, may have potential for cardiovascular risk prediction and - stratification. Cardiac troponin represents a highly sensitive and specific - marker of myocardial damage and is a current gold standard test for diagnosing - acute myocardial infarction in the general population. On the other hand, - natriuretic peptides, released from the heart secondary to increased left - ventricular wall stress, have emerged as a diagnostic marker for heart failure in - the general population. These two biomarkers reflect unique pathology of the - myocardium and are powerful prognostic markers in the dialysis population. This - article reviews the diagnostic potentials of these two cardiac biomarkers and - their clinical application in the dialysis population. -CI - © 2012 Wiley Periodicals, Inc. -FAU - Wang, Angela Yee-Moon -AU - Wang AY -AD - Department of Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam, - Hong Kong. aymwang@hku.hk -FAU - Wai-Kei Lam, Christopher -AU - Wai-Kei Lam C -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120702 -PL - United States -TA - Semin Dial -JT - Seminars in dialysis -JID - 8911629 -RN - 0 (Biomarkers) -RN - 0 (Peptide Fragments) -RN - 0 (Pro-BNP1-108) -RN - 0 (Troponin) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Biomarkers/blood -MH - Cardiovascular Diseases/*blood/complications/*diagnosis -MH - Humans -MH - Kidney Failure, Chronic/*complications -MH - Natriuretic Peptide, Brain/blood -MH - Peptide Fragments/blood -MH - Prognosis -MH - *Renal Dialysis -MH - Troponin/blood -EDAT- 2012/07/04 06:00 -MHDA- 2013/01/09 06:00 -CRDT- 2012/07/04 06:00 -PHST- 2012/07/04 06:00 [entrez] -PHST- 2012/07/04 06:00 [pubmed] -PHST- 2013/01/09 06:00 [medline] -AID - 10.1111/j.1525-139X.2012.01099.x [doi] -PST - ppublish -SO - Semin Dial. 2012 Jul;25(4):388-96. doi: 10.1111/j.1525-139X.2012.01099.x. Epub - 2012 Jul 2. - -PMID- 23543518 -OWN - NLM -STAT- MEDLINE -DCOM- 20130712 -LR - 20200511 -IS - 1469-493X (Electronic) -IS - 1361-6137 (Linking) -IP - 3 -DP - 2013 Mar 28 -TI - Artichoke leaf extract for treating hypercholesterolaemia. -PG - CD003335 -LID - 10.1002/14651858.CD003335.pub3 [doi] -AB - BACKGROUND: Hypercholesterolaemia is directly associated with an increased risk - for coronary heart disease and other sequelae of atherosclerosis. Artichoke leaf - extract (ALE) has been implicated in lowering cholesterol levels. Whether ALE is - truly effective for this indication is still a matter of debate. This is an - update of a review first published in 2002 and last updated in 2009. OBJECTIVES: - To assess the efficacy and safety of ALE in the treatment of - hypercholesterolaemia., SEARCH METHODS: We updated searches of the Cochrane - Central Register of Controlled Trials (CENTRAL, The Cochrane Library) (2012, - Issue 5); MEDLINE Ovid (1966 to May Week 2, 2012); EMBASE Ovid (1980 to 2012 Week - 19); and CINAHL Ebsco (1982 to May 2012) on 17 May 2012. CISCOM was last searched - until June 2001, and AMED until June 2008. We checked reference lists of - articles, and contacted manufacturers of preparations containing artichoke - extract, and experts on the subject. No language restrictions were applied. - SELECTION CRITERIA: We included randomised controlled trials (RCTs) of ALE - mono-preparations compared with placebo or reference medication for patients with - hypercholesterolaemia. We excluded trials assessing ALE as one of several active - components in a combination preparation or as a part of a combination treatment. - DATA COLLECTION AND ANALYSIS: Data were extracted systematically and risk of bias - was evaluated using the Cochrane 'Risk of bias' tool. Two authors independently - performed the screening of studies, selection, data extraction and assessment of - risk of bias. Disagreements in the evaluation of individual trials were resolved - through discussion. MAIN RESULTS: We included three RCTs involving 262 - participants. The trials were of adequate methodological quality but had some - shortcomings. One trial was at low quality of risk, one at medium and one of - unclear risk of bias. One trial is available as abstract only and includes a - small sample. In the first trial the total cholesterol level in participants - receiving ALE decreased by 4.2% from 7.16 (0.62) mmol/L to 6.86 (0.68) mmol/L - after 12 weeks, and increased from 6.90 (0.49) mmol/L to 7.04 (0.61) mmol/L in - patients receiving placebo, the total difference being statistically significant - (P = 0.025). In the second trial ALE reduced total cholesterol levels by 18.5% - from 7.74 mmol/L to 6.31 mmol/L after 42 ± 3 days of treatment, whereas placebo - reduced cholesterol by 8.6% from 7.69 mmol/L to 7.03 mmol/L (P = 0.00001). The - third trial, which is available as abstract only and provides limited data, - stated that ALE significantly reduced blood cholesterol compared with placebo in - a subgroup of patients with baseline total cholesterol levels of more than 230 - mg/dL (P < 0.05). Trial reports indicate mild, transient and infrequent adverse - events. AUTHORS' CONCLUSIONS: Data from three clinical trials assessing ALE for - treating hypercholesterolaemia are available. Athough the trials are of adequate - methodological quality they have some shortcomings and one is available as - abstract only. There is an indication that ALE has potential in lowering - cholesterol levels, but the evidence is, as yet, not convincing. The limited data - on safety suggest only mild, transient and infrequent adverse events with the - short term use of ALE. -FAU - Wider, Barbara -AU - Wider B -AD - Institute of Health Services Research, University of Exeter Medical School, - Exeter, UK. b.wider@exeter.ac.uk -FAU - Pittler, Max H -AU - Pittler MH -FAU - Thompson-Coon, Joanna -AU - Thompson-Coon J -FAU - Ernst, Edzard -AU - Ernst E -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -PT - Systematic Review -DEP - 20130328 -PL - England -TA - Cochrane Database Syst Rev -JT - The Cochrane database of systematic reviews -JID - 100909747 -RN - 0 (Plant Extracts) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -UOF - Cochrane Database Syst Rev. 2009 Oct 07;(4):CD003335. doi: - 10.1002/14651858.CD003335.pub2. PMID: 19821306 -UIN - Cochrane Database Syst Rev. 2016 May 19;(5):CD003335. doi: - 10.1002/14651858.CD003335.pub4. PMID: 27195440 -MH - Cholesterol/blood -MH - Cynara scolymus/*chemistry -MH - Humans -MH - Hypercholesterolemia/*drug therapy -MH - *Phytotherapy -MH - Plant Extracts/*therapeutic use -MH - Plant Leaves/*chemistry -MH - Randomized Controlled Trials as Topic -EDAT- 2013/04/02 06:00 -MHDA- 2013/07/16 06:00 -CRDT- 2013/04/02 06:00 -PHST- 2013/04/02 06:00 [entrez] -PHST- 2013/04/02 06:00 [pubmed] -PHST- 2013/07/16 06:00 [medline] -AID - 10.1002/14651858.CD003335.pub3 [doi] -PST - epublish -SO - Cochrane Database Syst Rev. 2013 Mar 28;(3):CD003335. doi: - 10.1002/14651858.CD003335.pub3. - -PMID- 17600563 -OWN - NLM -STAT- MEDLINE -DCOM- 20070816 -LR - 20151119 -IS - 0305-1870 (Print) -IS - 0305-1870 (Linking) -VI - 34 -IP - 8 -DP - 2007 Aug -TI - Raloxifene, tamoxifen and vascular tone. -PG - 809-13 -AB - 1. Oestrogen deficiency causes progressive reduction in endothelial function. - Despite the benefits of hormone-replacement therapy (HRT) evident in earlier - epidemiological studies, recent randomized trials of HRT for the prevention of - heart disease found no overall benefit. Instead, HRT users had higher incidences - of stroke and heart attack. Most women discontinue HRT because of its many - side-effects and/or the increased risk of breast and uterine cancer. This has - contributed to the development of selective oestrogen receptor modulators - (SERMs), such as tamoxifen and raloxifene, as alternative oestrogenic agents. 2. - A SERM is a molecule that binds with high affinity to oestrogen receptors but has - tissue-specific effects distinct from oestrogen, acting as an oestrogen agonist - in some tissues and as an antagonist in others. Clinical and animal studies - suggest multiple cardiovascular effects of SERMs. For example, raloxifene lowers - serum levels of cholesterol and homocysteine, attenuates oxidation of low-density - lipoprotein, inhibits endothelial-leucocyte interaction, improves endothelial - function and reduces vascular smooth muscle tone. 3. Available evidence suggests - that raloxifene and tamoxifen are capable of acting directly on both endothelial - cells and the underlying vascular smooth muscle cells and cause a multitude of - favourable modifications of the vascular wall, which jointly contribute to - improved local blood flow. The outcome of the Raloxifene Use for the Heart (RUTH) - trial will determine whether raloxifene, currently approved for the treatment of - post-menopausal osteoporosis, could substitute for HRT in alleviating - cardiovascular symptoms in post-menopausal women. -FAU - Leung, Fung Ping -AU - Leung FP -AD - Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, - Hong Kong SAR, China. -FAU - Tsang, Suk Ying -AU - Tsang SY -FAU - Wong, Chi Ming -AU - Wong CM -FAU - Yung, Lai Ming -AU - Yung LM -FAU - Chan, Yau Chi -AU - Chan YC -FAU - Leung, Hok Sum -AU - Leung HS -FAU - Yao, Xiaoqiang -AU - Yao X -FAU - Huang, Yu -AU - Huang Y -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Australia -TA - Clin Exp Pharmacol Physiol -JT - Clinical and experimental pharmacology & physiology -JID - 0425076 -RN - 0 (Cardiovascular Agents) -RN - 0 (Selective Estrogen Receptor Modulators) -RN - 094ZI81Y45 (Tamoxifen) -RN - 31C4KY9ESH (Nitric Oxide) -RN - 4F86W47BR6 (Raloxifene Hydrochloride) -SB - IM -MH - Animals -MH - Atherosclerosis/drug therapy/physiopathology -MH - Blood Vessels/*drug effects/metabolism -MH - Cardiovascular Agents/*pharmacology/therapeutic use -MH - Cardiovascular Diseases/drug therapy/physiopathology -MH - Cerebrovascular Circulation/drug effects -MH - Collateral Circulation/drug effects -MH - Coronary Circulation/drug effects -MH - Endothelium, Vascular/drug effects/metabolism -MH - *Estrogen Replacement Therapy -MH - Female -MH - Humans -MH - Nitric Oxide/metabolism -MH - Pulmonary Circulation/drug effects -MH - Raloxifene Hydrochloride/*pharmacology/therapeutic use -MH - Selective Estrogen Receptor Modulators/*pharmacology -MH - Tamoxifen/*pharmacology/therapeutic use -MH - Vasodilation/*drug effects -RF - 70 -EDAT- 2007/06/30 09:00 -MHDA- 2007/08/19 09:00 -CRDT- 2007/06/30 09:00 -PHST- 2007/06/30 09:00 [pubmed] -PHST- 2007/08/19 09:00 [medline] -PHST- 2007/06/30 09:00 [entrez] -AID - CEP4684 [pii] -AID - 10.1111/j.1440-1681.2007.04684.x [doi] -PST - ppublish -SO - Clin Exp Pharmacol Physiol. 2007 Aug;34(8):809-13. doi: - 10.1111/j.1440-1681.2007.04684.x. - -PMID- 23274306 -OWN - NLM -STAT- MEDLINE -DCOM- 20130624 -LR - 20220330 -IS - 1878-1810 (Electronic) -IS - 1931-5244 (Print) -IS - 1878-1810 (Linking) -VI - 161 -IP - 5 -DP - 2013 May -TI - MicroRNA regulation of cardiac conduction and arrhythmias. -PG - 381-92 -LID - S1931-5244(12)00418-5 [pii] -LID - 10.1016/j.trsl.2012.12.004 [doi] -AB - MicroRNAs are now recognized as important regulators of cardiovascular genes with - critical roles in normal development and physiology, as well as disease - development. MicroRNAs (miRNAs) are small noncoding RNAs approximately 22 - nucleotides in length that regulate expression of target genes through - sequence-specific hybridization to the 3' untranslated region of messenger RNAs - and either block translation or direct degradation of their target messenger RNA. - They have been shown to participate in cardiovascular disease pathogenesis - including atherosclerosis, coronary artery disease, myocardial infarction, heart - failure, and cardiac arrhythmias. Broadly defined, cardiac arrhythmias are a - variation from the normal heart rate or rhythm. Arrhythmias are common and result - in significant morbidity and mortality. Ventricular arrhythmias constitute a - major cause for cardiac death, particularly sudden cardiac death in the setting - of myocardial infarction and heart failure. As advances in pharmacologic, device, - and ablative therapy continue to evolve, the molecular insights into the basis of - arrhythmia is growing with the ambition of providing additional therapeutic - options. Electrical remodeling and structural remodeling are identified - mechanisms underlying arrhythmia generation; however, published studies focusing - on miRNAs and cardiac conduction are sparse. Recent studies have highlighted the - role of miRNAs in cardiac rhythm through regulation of key ion channels, - transporters, and cellular proteins in arrhythmogenic conditions. This article - aims to review the studies linking miRNAs to cardiac excitability and other - processes pertinent to arrhythmia. -CI - Copyright © 2013 Mosby, Inc. All rights reserved. -FAU - Kim, Gene H -AU - Kim GH -AD - University of Chicago, Institute for Cardiovascular Research, Chicago, IL 60637, - USA. gkim1@medicine.bsd.uchicago.edu -LA - eng -GR - K08 HL098565/HL/NHLBI NIH HHS/United States -GR - K08-HL098565/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121227 -PL - United States -TA - Transl Res -JT - Translational research : the journal of laboratory and clinical medicine -JID - 101280339 -RN - 0 (Ion Channels) -RN - 0 (MicroRNAs) -SB - IM -MH - Animals -MH - Arrhythmias, Cardiac/*genetics/*physiopathology/therapy -MH - Atrial Fibrillation/genetics/physiopathology -MH - Calcium Signaling/genetics/physiology -MH - Cell Communication/genetics/physiology -MH - Electrophysiological Phenomena -MH - Heart Conduction System/*physiology -MH - Humans -MH - Ion Channels/genetics/physiology -MH - MicroRNAs/antagonists & inhibitors/*genetics/*physiology -MH - Models, Cardiovascular -MH - Translational Research, Biomedical -PMC - PMC3619003 -MID - NIHMS427763 -EDAT- 2013/01/01 06:00 -MHDA- 2013/06/26 06:00 -PMCR- 2014/05/01 -CRDT- 2013/01/01 06:00 -PHST- 2012/08/28 00:00 [received] -PHST- 2012/12/04 00:00 [revised] -PHST- 2012/12/06 00:00 [accepted] -PHST- 2013/01/01 06:00 [entrez] -PHST- 2013/01/01 06:00 [pubmed] -PHST- 2013/06/26 06:00 [medline] -PHST- 2014/05/01 00:00 [pmc-release] -AID - S1931-5244(12)00418-5 [pii] -AID - 10.1016/j.trsl.2012.12.004 [doi] -PST - ppublish -SO - Transl Res. 2013 May;161(5):381-92. doi: 10.1016/j.trsl.2012.12.004. Epub 2012 - Dec 27. - -PMID- 22963620 -OWN - NLM -STAT- MEDLINE -DCOM- 20130328 -LR - 20190823 -IS - 1875-533X (Electronic) -IS - 0929-8673 (Linking) -VI - 19 -IP - 28 -DP - 2012 -TI - New clinical perspectives of hypolipidemic drug therapy in severe - hypercholesterolemia. -PG - 4861-8 -AB - Patients with homozygous familial hypercholesterolemia (HoFH) represent the most - severe patients within the spectrum of dyslipidemias. Untreated Low-Density - Lipoprotein Cholesterol (LDL-C) levels in these patients are usually in the range - 500 to 1200 mg/dL. Moreover, these patients exhibit a scarce responsiveness or - even non responsiveness to oral lipid lowering agents. Patients with heterozygous - familial hypercholesterolemia (HetFH) tend to have untreated LDL-C levels of - 250-500 mg/dL. Many of these patients are responsive to - 3-hydroxy-3-methylglutaryl-coenzyme A (HMGCoA-reductase) inhibitors (statins) - and/or other specific drugs. Unfortunately, a significant subset of these - patients (5-10%) have a severe and/or refractory form of HetFH and after current - maximal oral therapy, they remain significantly far from treatment goals (The - National Cholesterol Education Program (NCEP) ATPIII guidelines). This would be - defined as LDL-C levels of ≥ 190 mg/dL - prior Coronary Heart Disease (CHD) or - CHD equivalent - or ≥ 250 mg/dL (no prior CHD or CHD risk-equivalent). The only - current therapy option for these patients is Low Density Lipoprotein-apheresis - (LDL_a). While LDL_a is very effective in reducing LDL-C, many patients do not - receive this extracorporeal therapy because of costs and limited availability of - LDL_a centers. Recently, new potent lipid-lowering drugs have been developed and - are currently under investigation. Proprotein convertase subtilisin/kexin type 9 - (PCSK9) plays a critical role controlling the levels of LDL-C. Studies have - demonstrated that PCSK9 acts mainly by enhancing degradation of the Low-Density - Lipoprotein receptor (LDLR) protein in the liver. Inactivation of PCSK9 in mice - reduces plasma cholesterol levels. Since the loss of a functional PCSK9 in human - is not associated with apparent deleterious effects, this protease is becoming an - attractive target for lowering plasma LDL-C levels either alone or in combination - with statins. Mipomersen, an apolipoprotein B (ApoB) synthesis inhibitor, for - lowering of LDL-C showed to be an effective therapy to reduce LDL-C - concentrations in patients with HoFH who are already receiving lipid-lowering - drugs, including high-dose statins. Lomitapide is a potent inhibitor of - microsomal triglyceride transfer protein and is highly efficacious in reducing - LDL-C and triglycerides (TG). Lomitapide is currently being developed for - patients with HoFH at doses up to 60 mg/d. These new powerful lipid-lowering - drugs might be possibly superior than available hypolipidemic agents. Their - mechanisms of action, effectiveness, safety, and indication in severe, - genetically determined dyslipidemias, are reviewed. -FAU - Stefanutti, C -AU - Stefanutti C -AD - Extracorporeal Therapeutic Techniques Unit, Department of Molecular Medicine, - University of Rome 'Sapienza', 'Umberto I' Hospital, Rome, Italy. - csefanutti@alice.it -FAU - Morozzi, C -AU - Morozzi C -FAU - Di Giacomo, S -AU - Di Giacomo S -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Hypolipidemic Agents) -RN - 0 (Oligonucleotides) -RN - 0 (Receptors, LDL) -RN - 9GJ8S4GU0M (mipomersen) -RN - EC 1.1.1.- (Hydroxymethylglutaryl CoA Reductases) -RN - EC 3.4.21.- (Proprotein Convertases) -SB - IM -MH - Cholesterol, LDL/blood -MH - Humans -MH - Hydroxymethylglutaryl CoA Reductases/chemistry/metabolism -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/chemistry/therapeutic use -MH - Hypercholesterolemia/*drug therapy -MH - Hypolipidemic Agents/*therapeutic use -MH - Microsomes/metabolism -MH - Oligonucleotides/chemistry/therapeutic use -MH - Proprotein Convertases/antagonists & inhibitors/metabolism -MH - Receptors, LDL/genetics/metabolism -EDAT- 2012/09/12 06:00 -MHDA- 2013/03/30 06:00 -CRDT- 2012/09/12 06:00 -PHST- 2012/03/06 00:00 [received] -PHST- 2012/06/04 00:00 [revised] -PHST- 2012/08/27 00:00 [accepted] -PHST- 2012/09/12 06:00 [entrez] -PHST- 2012/09/12 06:00 [pubmed] -PHST- 2013/03/30 06:00 [medline] -AID - CMC-EPUB-20120903-2 [pii] -AID - 10.2174/092986712803341485 [doi] -PST - ppublish -SO - Curr Med Chem. 2012;19(28):4861-8. doi: 10.2174/092986712803341485. - -PMID- 18035865 -OWN - NLM -STAT- MEDLINE -DCOM- 20080124 -LR - 20220311 -IS - 0114-5916 (Print) -IS - 0114-5916 (Linking) -VI - 30 -IP - 12 -DP - 2007 -TI - Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes - mellitus. -PG - 1127-42 -AB - The majority of patients with type 2 diabetes mellitus are overweight or obese at - the time of diagnosis, and obesity is a recognised risk factor for type 2 - diabetes and coronary heart disease (CHD). Conversely, weight loss has been shown - to improve glycaemic control in patients with type 2 diabetes, as well as to - lower the risk of CHD. The traditional pharmacotherapies for type 2 diabetes can - further increase weight and this may undermine the benefits of improved glycaemic - control. Furthermore, patients' desire to avoid weight gain may jeopardise - compliance with treatment, thereby limiting treatment success and indirectly - increasing the risk of long-term complications. This review evaluates the - influences of established and emerging therapies on bodyweight in type 2 - diabetes. Improvement in glycaemic control with insulin secretagogues has been - associated with weight gain. On the other hand, biguanides such as metformin have - been consistently shown to have a beneficial effect on weight; metformin appears - to modestly reduce weight when used as a monotherapy. alpha-Glucosidase - inhibitors are considered weight neutral; in fact, the results of some studies - show that they cause reductions in weight. Thiazolidinediones (TZDs) are - typically associated with weight gain and increased risk of oedema, while the - impact of some TZDs, such as pioglitazone, on lipid homeostasis could be - beneficial. Insulin, the most effective therapy when oral agents are ineffective, - has always been linked to significant weight gain. Newly developed insulin - analogues can lower the risk of hypoglycaemia compared with human insulin, but - most have no advantage in terms of weight gain. The basal analogue insulin - detemir, however, has been demonstrated to cause weight gain to a lesser extent - than human insulin. The emerging treatments, such as glucagon-like peptide-1 - agonists and the amylin analogue, pramlintide, seem able to decrease weight in - patients with type 2 diabetes, whereas dipeptidyl peptidase-4 inhibitors seem to - be weight neutral. In summary, while reduction of hyperglycaemia remains the - foremost goal in the treatment of patients with type 2 diabetes, the avoidance of - weight gain may be a clinically important secondary goal. This is already - possible with careful selection of available therapies, while several emerging - therapies promise to further extend the options available. -FAU - Hermansen, Kjeld -AU - Hermansen K -AD - Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus, - Denmark. kjeld.hermansen@as.aaa.dk -FAU - Mortensen, Lene S -AU - Mortensen LS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - New Zealand -TA - Drug Saf -JT - Drug safety -JID - 9002928 -RN - 0 (Amyloid) -RN - 0 (Benzamides) -RN - 0 (Biguanides) -RN - 0 (Dipeptidyl-Peptidase IV Inhibitors) -RN - 0 (Glycoside Hydrolase Inhibitors) -RN - 0 (Hypoglycemic Agents) -RN - 0 (Insulin) -RN - 0 (Islet Amyloid Polypeptide) -RN - 0 (Sulfonylurea Compounds) -RN - 0 (Thiazolidinediones) -RN - 89750-14-1 (Glucagon-Like Peptide 1) -RN - 8V6OK1I088 (meglitinide) -SB - IM -MH - Amyloid/therapeutic use -MH - Benzamides/adverse effects/therapeutic use -MH - Biguanides/therapeutic use -MH - Body Weight/*drug effects -MH - Diabetes Mellitus, Type 2/*drug therapy -MH - Dipeptidyl-Peptidase IV Inhibitors/therapeutic use -MH - Glucagon-Like Peptide 1/agonists -MH - Glycoside Hydrolase Inhibitors -MH - Humans -MH - Hypoglycemic Agents/administration & dosage/*adverse effects/*therapeutic use -MH - Insulin/adverse effects/analogs & derivatives/metabolism/therapeutic use -MH - Insulin Secretion -MH - Islet Amyloid Polypeptide -MH - Obesity/*chemically induced -MH - Sulfonylurea Compounds/adverse effects/therapeutic use -MH - Thiazolidinediones/adverse effects/therapeutic use -MH - Weight Gain -RF - 122 -EDAT- 2007/11/27 09:00 -MHDA- 2008/01/25 09:00 -CRDT- 2007/11/27 09:00 -PHST- 2007/11/27 09:00 [pubmed] -PHST- 2008/01/25 09:00 [medline] -PHST- 2007/11/27 09:00 [entrez] -AID - 30125 [pii] -AID - 10.2165/00002018-200730120-00005 [doi] -PST - ppublish -SO - Drug Saf. 2007;30(12):1127-42. doi: 10.2165/00002018-200730120-00005. - -PMID- 21988275 -OWN - NLM -STAT- MEDLINE -DCOM- 20120502 -LR - 20250529 -IS - 1557-8593 (Electronic) -IS - 1520-9156 (Linking) -VI - 14 -IP - 1 -DP - 2012 Jan -TI - Consensus physical activity guidelines for Asian Indians. -PG - 83-98 -LID - 10.1089/dia.2011.0111 [doi] -AB - India is currently undergoing rapid economic, demographic, and lifestyle - transformations. A key feature of the latter transformation has been - inappropriate and inadequate diets and decreases in physical activity. Data from - various parts of India have shown a steady increase in the prevalence of - lifestyle-related diseases such as type 2 diabetes mellitus (T2DM), the metabolic - syndrome, hypertension, coronary heart disease (CHD), etc., frequently in - association with overweight or obesity. Comparative data show that Asian Indians - are more sedentary than white Caucasians. In this review, the Consensus Group - considered the available physical activity guidelines from international and - Indian studies and formulated India-specific guidelines. A total of 60 min of - physical activity is recommended every day for healthy Asian Indians in view of - the high predisposition to develop T2DM and CHD. This should include at least - 30 min of moderate-intensity aerobic activity, 15 min of work-related activity, - and 15 min of muscle-strengthening exercises. For children, moderate-intensity - physical activity for 60 min daily should be in the form of sport and physical - activity. This consensus statement also includes physical activity guidelines for - pregnant women, the elderly, and those suffering from obesity, T2DM, CHD, etc. - Proper application of guidelines is likely to have a significant impact on the - prevalence and management of obesity, the metabolic syndrome, T2DM, and CHD in - Asian Indians. -FAU - Misra, Anoop -AU - Misra A -AD - Fortis-CDOC Center of Excellence for Diabetes, Metabolic Diseases and - Endocrinology, Fortis Flt. Lt. Rajan Dhall Hospital, New Delhi, India. - anoopmisra@metabolicresearchindia.com -FAU - Nigam, Priyanka -AU - Nigam P -FAU - Hills, Andrew P -AU - Hills AP -FAU - Chadha, Davinder S -AU - Chadha DS -FAU - Sharma, Vineeta -AU - Sharma V -FAU - Deepak, K K -AU - Deepak KK -FAU - Vikram, Naval K -AU - Vikram NK -FAU - Joshi, Shashank -AU - Joshi S -FAU - Chauhan, Ashish -AU - Chauhan A -FAU - Khanna, Kumud -AU - Khanna K -FAU - Sharma, Rekha -AU - Sharma R -FAU - Mittal, Kanchan -AU - Mittal K -FAU - Passi, Santosh Jain -AU - Passi SJ -FAU - Seth, Veenu -AU - Seth V -FAU - Puri, Seema -AU - Puri S -FAU - Devi, Ratna -AU - Devi R -FAU - Dubey, A P -AU - Dubey AP -FAU - Gupta, Sunita -AU - Gupta S -CN - Physical Activity Consensus Group -LA - eng -GR - MC_UP_A100_1003/MRC_/Medical Research Council/United Kingdom -PT - Consensus Development Conference -PT - Journal Article -PT - Practice Guideline -PT - Review -DEP - 20111011 -PL - United States -TA - Diabetes Technol Ther -JT - Diabetes technology & therapeutics -JID - 100889084 -SB - IM -MH - *Consensus -MH - Diabetes Mellitus, Type 2/*epidemiology/ethnology/*prevention & control -MH - Female -MH - Humans -MH - India/epidemiology -MH - Male -MH - *Motor Activity -MH - Obesity/*epidemiology/ethnology/*prevention & control -MH - Prevalence -MH - Risk Reduction Behavior -FIR - Misra, Anoop -IR - Misra A -FIR - Nigam, Priyanka -IR - Nigam P -FIR - Hills, Andrew P -IR - Hills AP -FIR - Chadha, Davinder S -IR - Chadha DS -FIR - Misra, Anoop -IR - Misra A -FIR - Nigam, Priyanka -IR - Nigam P -FIR - Hills, Andrew P -IR - Hills AP -FIR - Chadha, Davinder S -IR - Chadha DS -FIR - Misra, Anoop -IR - Misra A -FIR - Nigam, Priyanka -IR - Nigam P -FIR - Hills, Andrew P -IR - Hills AP -FIR - Chadha, Davinder S -IR - Chadha DS -FIR - Sharma, Vineeta -IR - Sharma V -FIR - Deepak, K K -IR - Deepak KK -FIR - Vikram, Naval K -IR - Vikram NK -FIR - Joshi, Shashank -IR - Joshi S -FIR - Chauhan, Ashish -IR - Chauhan A -FIR - Khanna, Kumud -IR - Khanna K -FIR - Sharma, Rekha -IR - Sharma R -FIR - Mittal, Kanchan -IR - Mittal K -FIR - Passi, Santosh Jain -IR - Passi SJ -FIR - Seth, Veenu -IR - Seth V -FIR - Puri, Seema -IR - Puri S -FIR - Devi, Ratna -IR - Devi R -FIR - Dubey, A P -IR - Dubey AP -FIR - Gupta, Sunita -IR - Gupta S -FIR - Dubey, A P -IR - Dubey AP -FIR - Saxena, A -IR - Saxena A -FIR - Saxena, Abha -IR - Saxena A -FIR - Malaviya, Anand N -IR - Malaviya AN -FIR - Ghei, Anju -IR - Ghei A -FIR - Kurpad, Anura -IR - Kurpad A -FIR - Chauhan, Ashish -IR - Chauhan A -FIR - Duggal, Ashok Kumar -IR - Duggal AK -FIR - Trisal, Ashok -IR - Trisal A -FIR - Pandav, C S -IR - Pandav CS -FIR - Sekhar, Chandra -IR - Sekhar C -FIR - Arora, D D -IR - Arora DD -FIR - Kapur, Deeksha -IR - Kapur D -FIR - Bhatia, Dheeraj -IR - Bhatia D -FIR - Mathur, G M -IR - Mathur GM -FIR - Singh, G M -IR - Singh GM -FIR - Sridhar, G R -IR - Sridhar GR -FIR - Kashiva, Isha -IR - Kashiva I -FIR - Bahnot, J M -IR - Bahnot JM -FIR - Madan, Jagmeet -IR - Madan J -FIR - Kaur, Jasmin -IR - Kaur J -FIR - Mathew, Jeena -IR - Mathew J -FIR - das Gupta, Jharna -IR - das Gupta J -FIR - Pant, K K -IR - Pant KK -FIR - Shukla, K K -IR - Shukla KK -FIR - Mittal, Kanchan -IR - Mittal K -FIR - Kapoor, Kanika -IR - Kapoor K -FIR - Madan, Kaushal -IR - Madan K -FIR - Khanna, Kumud -IR - Khanna K -FIR - Pant, Lokesh -IR - Pant L -FIR - Pant, Lokesh -IR - Pant L -FIR - Misra, M N -IR - Misra MN -FIR - Munral, Mala -IR - Munral M -FIR - Chaudhary, Manu -IR - Chaudhary M -FIR - Khurshid, Md -IR - Khurshid M -FIR - Sharma, Meenakshi -IR - Sharma M -FIR - Mathur, Mathur -IR - Mathur M -FIR - Chandra, Mekhala -IR - Chandra M -FIR - Bhatia, Nammita -IR - Bhatia N -FIR - Chawla, Naresh -IR - Chawla N -FIR - Vikram, Naval K -IR - Vikram NK -FIR - Singh, Neelanjana -IR - Singh N -FIR - Gupta, Neha -IR - Gupta N -FIR - Kaushik, Nidhi -IR - Kaushik N -FIR - Sharma, Nidhi -IR - Sharma N -FIR - Gupta, Nikhil -IR - Gupta N -FIR - Mishra, P H -IR - Mishra PH -FIR - Singh, Padam -IR - Singh P -FIR - Puri, Pooja -IR - Puri P -FIR - Shah, Priyali -IR - Shah P -FIR - Misra, Puneet -IR - Misra P -FIR - Lall, R C -IR - Lall RC -FIR - Parikh, Rakesh -IR - Parikh R -FIR - Mohan, Ramesh -IR - Mohan R -FIR - Devi, Ratna -IR - Devi R -FIR - Upadhaya, Ravi -IR - Upadhaya R -FIR - Gupta, Ritesh -IR - Gupta R -FIR - Jain, Ritu -IR - Jain R -FIR - Guglani, Ruchika -IR - Guglani R -FIR - Agarwal, S K -IR - Agarwal SK -FIR - Passi, Santosh J -IR - Passi SJ -FIR - Sarkar, Sarswati -IR - Sarkar S -FIR - Mukhopadhyay, Satinath -IR - Mukhopadhyay S -FIR - Puri, Seema -IR - Puri S -FIR - Gulati, Seema -IR - Gulati S -FIR - Gupta, Shashi P -IR - Gupta SP -FIR - Joshi, Shashank -IR - Joshi S -FIR - Nuna, Sheel -IR - Nuna S -FIR - Saluja, Shelza -IR - Saluja S -FIR - Joshi, Shilpa -IR - Joshi S -FIR - Atrey, Shubhra -IR - Atrey S -FIR - Madhusudan, Shuchee -IR - Madhusudan S -FIR - Dixit, Smita -IR - Dixit S -FIR - Gupta, Sonal -IR - Gupta S -FIR - Sharma, Srikant -IR - Sharma S -FIR - Majumdar, Subir -IR - Majumdar S -FIR - Gupta, Sunita -IR - Gupta S -FIR - Singh, Suruchi -IR - Singh S -FIR - Bhatt, Surya P -IR - Bhatt SP -FIR - Colles, Susan L -IR - Colles SL -FIR - Bharadwaj, Swati -IR - Bharadwaj S -FIR - Seth, Veenu -IR - Seth V -FIR - Vidya -IR - Vidya -FIR - Zargar, Abdul Hamid -IR - Zargar AH -FIR - Sood, Ajay -IR - Sood A -FIR - Bhoraskar, Anil -IR - Bhoraskar A -FIR - Bhargava, Anuj -IR - Bhargava A -FIR - Patel, Anushka -IR - Patel A -FIR - Vasudevan, Deepa -IR - Vasudevan D -FIR - Enas, Enas -IR - Enas E -FIR - Ahmad, Jamal -IR - Ahmad J -FIR - Vora, Jiten -IR - Vora J -FIR - Vijay, Kris -IR - Vijay K -FIR - Soares, Mario -IR - Soares M -FIR - Misra, Ranjita -IR - Misra R -FIR - Das, Undurti N -IR - Das UN -FIR - Dhurandhar, Nikhil -IR - Dhurandhar N -FIR - Forouhi, Nita -IR - Forouhi N -FIR - Ganda, Om -IR - Ganda O -FIR - Deedwania, Prakash -IR - Deedwania P -FIR - Bhopal, Raj -IR - Bhopal R -FIR - Khardori, Romesh -IR - Khardori R -FIR - Jesmin, Subrina -IR - Jesmin S -FIR - Anand, Sonia -IR - Anand S -FIR - Mudaliar, Sundar -IR - Mudaliar S -FIR - Viswanathan, Vijay -IR - Viswanathan V -FIR - Fonseca, Vivian -IR - Fonseca V -EDAT- 2011/10/13 06:00 -MHDA- 2012/05/04 06:00 -CRDT- 2011/10/13 06:00 -PHST- 2011/10/13 06:00 [entrez] -PHST- 2011/10/13 06:00 [pubmed] -PHST- 2012/05/04 06:00 [medline] -AID - 10.1089/dia.2011.0111 [doi] -PST - ppublish -SO - Diabetes Technol Ther. 2012 Jan;14(1):83-98. doi: 10.1089/dia.2011.0111. Epub - 2011 Oct 11. - -PMID- 19653170 -OWN - NLM -STAT- MEDLINE -DCOM- 20091021 -LR - 20131121 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 16 -IP - 4 -DP - 2009 -TI - Hormonal profiles behind the heart of a man. -PG - 300-6 -AB - This study focuses on the role of sex steroids on the libido, sexual life, - emotional and physiological heart of men of all ages. Sex steroids play a - significant role throughout a man's life, with a gradual decline in old age. The - foetal testis secretes testosterone and dehydroepiandrosterone at about nine - weeks gestation. At puberty, testosterone increases dramatically in boys. Changes - in weight and height of boys across this period are associated with increasing - testosterone concentration and sex hormone binding globulin (SHBG). Romantic - thoughts, fantasy, and sexual pleasure-seeking behaviour in adolescents are - associated with exposure to high androgens secretion. Thus, the libido and sexual - life of a man is initiated and maintained by testosterone and SHBG. Lower - testosterone levels are associated with erectile dysfunction among other risk - factors: diabetes, hypertension, heart disease, psychological stress and obesity. - Men with proven coronary atherosclerosis have lower levels of testosterone and - SHBG, which have negative correlation with very low-density lipoprotein, - triglycerides, body mass index and body fat mass. These are some of the risk - factors for cardiovascular diseases. Thus, in men, endogenous sex steroids impart - beneficial effects on the heart. How exactly endogenous sex steroids act on the - heart is not clear. Further study is needed to understand the interaction between - endogenous sex steroids, higher centers in the brain and the heart of a man. -FAU - Sarkar, Narendra Nath -AU - Sarkar NN -AD - Department of Reproductive Biology, All India Institute of Medical Sciences, New - Delhi, India. n_n_Sarkar@yahoo.co.in -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -RN - 0 (Sex Hormone-Binding Globulin) -RN - 3XMK78S47O (Testosterone) -SB - IM -MH - Adolescent -MH - Adult -MH - Aged -MH - Cardiovascular Diseases/epidemiology/*physiopathology -MH - Child -MH - Humans -MH - Male -MH - Puberty/*physiology -MH - Risk Factors -MH - Sex Hormone-Binding Globulin/*physiology -MH - Testis/embryology/growth & development/*physiology -MH - Testosterone/*physiology -RF - 31 -EDAT- 2009/08/05 09:00 -MHDA- 2009/10/22 06:00 -CRDT- 2009/08/05 09:00 -PHST- 2009/08/05 09:00 [entrez] -PHST- 2009/08/05 09:00 [pubmed] -PHST- 2009/10/22 06:00 [medline] -PST - ppublish -SO - Cardiol J. 2009;16(4):300-6. - -PMID- 16924166 -OWN - NLM -STAT- MEDLINE -DCOM- 20060912 -LR - 20151119 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 14 -IP - 5 -DP - 2006 Sep-Oct -TI - Nebivolol: new therapy update. -PG - 259-64 -AB - Nebivolol is a beta-blocker under U.S. Food and Drug Administration review for - the treatment of hypertension. The unique pharmacologic properties of nebivolol - include high specificity for the beta-1 receptor and a nitric oxide-mediated - vasodilatory effect. The agent provides significant blood pressure reduction from - baseline values as compared with placebo. Clinical trials have demonstrated that - nebivolol reduces blood pressure similarly to atenolol, bisoprolol, amlodipine, - nifedipine, lisinopril, and hydrochlorothiazide. The tolerability of nebivolol is - similar to or better than that of these agents. In elderly patients (> or = 70 - years of age) with clinically stable congestive heart failure, the addition of - nebivolol to the treatment regimen improved the time to all-cause mortality and - cardiovascular hospital admissions over that of placebo. If approved, nebivolol - would likely be a viable alternative therapy for hypertension and heart failure; - however, additional studies are needed in patients having coronary artery - disease. -FAU - Sule, Sachin S -AU - Sule SS -AD - Department of Medicine, New York Medical College/Westchester Medical Center, - Valhalla, New York, USA. -FAU - Frishman, William -AU - Frishman W -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Benzopyrans) -RN - 0 (Ethanolamines) -RN - 030Y90569U (Nebivolol) -SB - IM -MH - Adrenergic beta-Antagonists/adverse - effects/chemistry/pharmacokinetics/*therapeutic use -MH - Benzopyrans/adverse effects/chemistry/pharmacokinetics/*therapeutic use -MH - Blood Pressure/drug effects/physiology -MH - Clinical Trials as Topic -MH - Dose-Response Relationship, Drug -MH - Drug Interactions -MH - Ethanolamines/adverse effects/chemistry/pharmacokinetics/*therapeutic use -MH - Heart Failure/drug therapy/physiopathology -MH - Humans -MH - Hypertension/*drug therapy/physiopathology -MH - Nebivolol -MH - Vasodilation/drug effects/physiology -RF - 71 -EDAT- 2006/08/23 09:00 -MHDA- 2006/09/13 09:00 -CRDT- 2006/08/23 09:00 -PHST- 2006/08/23 09:00 [pubmed] -PHST- 2006/09/13 09:00 [medline] -PHST- 2006/08/23 09:00 [entrez] -AID - 00045415-200609000-00007 [pii] -AID - 10.1097/01.crd.0000223651.03023.8e [doi] -PST - ppublish -SO - Cardiol Rev. 2006 Sep-Oct;14(5):259-64. doi: 10.1097/01.crd.0000223651.03023.8e. - -PMID- 18448821 -OWN - NLM -STAT- MEDLINE -DCOM- 20080812 -LR - 20171116 -IS - 0077-8923 (Print) -IS - 0077-8923 (Linking) -VI - 1126 -DP - 2008 Apr -TI - Advanced glycation endproducts in chronic heart failure. -PG - 225-30 -LID - 10.1196/annals.1433.038 [doi] -AB - Advanced glycation endproducts (AGEs) have been proposed as factors involved in - the development and progression of chronic heart failure (CHF). Cross-linking by - AGEs results in vascular and myocardial stiffening, which are hallmarks in the - pathogenesis of CHF. Additionally, stimulation of receptors by AGEs may affect - endothelial function and myocardial calcium uptake and may perpetuate coronary - sclerosis in CHF. CHF is common in conditions with AGE accumulation, such as - diabetes and renal failure. This review describes in detail the interrelation of - plasma AGEs, renal function, and the severity and prognosis in clinical CHF - patients with mild to moderate loss of renal function. This association is - compared with the relation between tissue AGE accumulation (marked by skin - autofluorescence) and diastolic dysfunction in renal failure. The evidence - reviewed here provides support for the assumed role of AGEs in determining the - severity and prognosis of CHF, but also highlights the differences in this - relation between plasma and tissue AGEs and between patients with and without - advanced renal failure. Ongoing clinical intervention trials to reduce AGE - accumulation in patients with CHF may elucidate the causal role of AGEs in the - development and course of CHF. -FAU - Smit, Andries J -AU - Smit AJ -AD - Department of Medicine, University Medical Center Groningen, Groningen, the - Netherlands. a.j.smit@int.umcg.nl -FAU - Hartog, Jasper W L -AU - Hartog JW -FAU - Voors, Adriaan A -AU - Voors AA -FAU - van Veldhuisen, Dirk J -AU - van Veldhuisen DJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Ann N Y Acad Sci -JT - Annals of the New York Academy of Sciences -JID - 7506858 -RN - 0 (Glycation End Products, Advanced) -SB - IM -MH - Chronic Disease -MH - Diastole/*physiology -MH - Glycation End Products, Advanced/adverse effects/*metabolism -MH - Heart Failure/*epidemiology/*physiopathology -MH - Humans -MH - Systole/*physiology -RF - 35 -EDAT- 2008/05/02 09:00 -MHDA- 2008/08/13 09:00 -CRDT- 2008/05/02 09:00 -PHST- 2008/05/02 09:00 [pubmed] -PHST- 2008/08/13 09:00 [medline] -PHST- 2008/05/02 09:00 [entrez] -AID - 1126/1/225 [pii] -AID - 10.1196/annals.1433.038 [doi] -PST - ppublish -SO - Ann N Y Acad Sci. 2008 Apr;1126:225-30. doi: 10.1196/annals.1433.038. - -PMID- 19281913 -OWN - NLM -STAT- MEDLINE -DCOM- 20090915 -LR - 20131121 -IS - 1879-114X (Electronic) -IS - 0149-2918 (Linking) -VI - 30 Pt 2 -DP - 2008 -TI - Angiotensin II receptor blockers in the treatment of the cardiovascular disease - continuum. -PG - 2181-90 -LID - 10.1016/j.clinthera.2008.12.002 [doi] -AB - BACKGROUND: The cardiovascular disease (CVD) continuum is a chain of events that - begins with a host of risk factors, including dyslipidemia, hypertension, - diabetes, visceral obesity, and smoking. If left untreated, it might progress to - atherosclerosis, left ventricular hypertrophy, coronary artery disease, - myocardial infarction, left ventricular remodeling, left ventricular enlargement, - and eventually endstage heart disease and death. Initiation of treatment, at any - stage in its course, might prevent or delay its further progression. OBJECTIVE: - This review discusses data from doubleblind, randomized controlled trials (RCTs) - that have investigated the effects of angiotensin II receptor blockers (ARBs) on - various stages of the CVD continuum. METHODS: PubMed/MEDLINE was searched for - relevant English-language double-blind RCTs using the years 1995 to 2008 and the - terms angiotensin type II receptor blocker, renin-angiotensin system, - hypertension, heart failure, left ventricular hypertropby, renal disease, stroke, - and cerebrovascular disease. RESULTS: A total of 13 studies were included in this - review. The results suggest that ARB-based therapy has cardioprotective, - cerebroprotective, and renoprotective effects, including regression of left - ventricular hypertrophy, reduction in the risk of stroke, and slowing of the - progression of renal disease. CONCLUSIONS: Treatment of CVD risk factors, - including hypertension, is increasingly recognized as a way to interrupt the CVD - continuum. Activation of the renin-angiotensin system (RAS) contributes to the - development and progression of CVD, and RAS blockade has been reported to be - beneficial at all stages of the CVD continuum. -FAU - Chrysant, Steven G -AU - Chrysant SG -AD - Oklahoma Cardiovascular and Hypertension Center and University of Oklahoma School - of Medicine, Oklahoma City, Oklahoma, USA. schrysant@yahoo.com -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Clin Ther -JT - Clinical therapeutics -JID - 7706726 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - AYI8EX34EU (Creatinine) -SB - IM -MH - Albuminuria -MH - Angiotensin II Type 1 Receptor Blockers/*therapeutic use -MH - Cardiovascular Diseases/physiopathology/*prevention & control -MH - Creatinine/blood -MH - Disease Progression -MH - Humans -MH - Hypertension/drug therapy/physiopathology -MH - Kidney Diseases/prevention & control -MH - Randomized Controlled Trials as Topic -MH - Renin-Angiotensin System/drug effects/physiology -MH - Risk Factors -MH - Stroke/prevention & control -RF - 60 -EDAT- 2008/01/01 00:00 -MHDA- 2009/09/16 06:00 -CRDT- 2009/03/14 09:00 -PHST- 2008/10/03 00:00 [accepted] -PHST- 2009/03/14 09:00 [entrez] -PHST- 2008/01/01 00:00 [pubmed] -PHST- 2009/09/16 06:00 [medline] -AID - S0149-2918(08)00416-5 [pii] -AID - 10.1016/j.clinthera.2008.12.002 [doi] -PST - ppublish -SO - Clin Ther. 2008;30 Pt 2:2181-90. doi: 10.1016/j.clinthera.2008.12.002. - -PMID- 20410547 -OWN - NLM -STAT- MEDLINE -DCOM- 20100729 -LR - 20190101 -IS - 1535-2900 (Electronic) -IS - 1079-2082 (Linking) -VI - 67 -IP - 9 -DP - 2010 May 1 -TI - Safety of fixed-dose aspirin-extended-release dipyridamole in patients with - ischemic heart disease. -PG - 728-33 -LID - 10.2146/ajhp080645 [doi] -AB - PURPOSE: The safety of fixed-dose combination aspirin-extended-release (ER) - dipyridamole for stroke prevention in patients with ischemic heart disease is - reviewed. SUMMARY: Randomized controlled trials have established the superiority - of aspirinER dipyridamole over aspirin alone for secondary stroke prevention. One - limitation of this product is the potential risk of worsening angina in patients - with coronary artery disease. The English-language medical literature was - searched for articles describing the cardiac safety of oral dipyridamole alone or - in combination with aspirin. Meta-analyses, randomized controlled trials, - observational studies, and case reports presenting information on the cardiac - safety of oral dipyridamole were also reviewed. Four meta-analyses described - vascular events with dipyridamole using various dosing strategies. Three trials - included the endpoint of myocardial infarction in patients receiving ER - dipyridamole. The meta-analyses and randomized controlled trials specifically - evaluating aspirin-ER dipyridamole did not provide evidence of increased risk of - vascular events. One post hoc analysis of a randomized controlled trial - specifically assessed the cardiac safety of fixed-dose aspirin-ER dipyridamole - and found that dipyridamole was not associated with a higher number of cardiac - events compared with aspirin alone. One randomized controlled trial evaluated the - efficacy of ER dipyridamole in patients with preexisting ischemic heart disease - and found no evidence of increased risk of cardiac events in this population. No - published reports were located describing angina with the combination product. - CONCLUSION: A literature review revealed that fixed-dose aspirin-ER dipyridamole - was not associated with an increased risk of cardiovascular events in patients - with ischemic heart disease. However, individual patient factors merit - consideration when choosing an antiplatelet agent for stroke prevention. -FAU - Crown, Natalie -AU - Crown N -AD - Pharmacy Services, London Health Sciences Centre, London, Ontario, Canada. -FAU - Mysak, Tania -AU - Mysak T -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Am J Health Syst Pharm -JT - American journal of health-system pharmacy : AJHP : official journal of the - American Society of Health-System Pharmacists -JID - 9503023 -RN - 0 (Aspirin, Dipyridamole Drug Combination) -RN - 0 (Drug Combinations) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 64ALC7F90C (Dipyridamole) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Aspirin/administration & dosage/adverse effects/*therapeutic use -MH - Aspirin, Dipyridamole Drug Combination -MH - Dipyridamole/administration & dosage/adverse effects/*therapeutic use -MH - Drug Combinations -MH - *Drug-Related Side Effects and Adverse Reactions -MH - Humans -MH - Meta-Analysis as Topic -MH - Myocardial Ischemia/*drug therapy -MH - Platelet Aggregation Inhibitors/administration & dosage/adverse - effects/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Stroke/prevention & control -RF - 28 -EDAT- 2010/04/23 06:00 -MHDA- 2010/07/30 06:00 -CRDT- 2010/04/23 06:00 -PHST- 2010/04/23 06:00 [entrez] -PHST- 2010/04/23 06:00 [pubmed] -PHST- 2010/07/30 06:00 [medline] -AID - 67/9/728 [pii] -AID - 10.2146/ajhp080645 [doi] -PST - ppublish -SO - Am J Health Syst Pharm. 2010 May 1;67(9):728-33. doi: 10.2146/ajhp080645. - -PMID- 18003665 -OWN - NLM -STAT- MEDLINE -DCOM- 20080715 -LR - 20220310 -IS - 1460-2385 (Electronic) -IS - 0931-0509 (Linking) -VI - 23 -IP - 2 -DP - 2008 Feb -TI - Heart rate variability (HRV) in kidney failure: measurement and consequences of - reduced HRV. -PG - 444-9 -AB - A common cause of death in end-stage renal disease (ESRD) patients on dialysis is - sudden cardiac death (SCD). Compared to the general population, the percentage of - cardiovascular deaths that are attributed to SCD is higher in patients treated by - dialysis. While coronary artery disease (CAD) is the predominant cause of SCD in - dialysis patients, reduced heart rate variability (HRV) may play a role in the - higher risk of SCD among other risk factors. HRV refers to beat-to-beat - alterations in heart rate as measured by periodic variation in the R-R interval. - HRV provides a non-invasive method for investigating autonomic input into the - heart. It quantifies the amount by which the R-R interval or heart rate changes - from one cardiac cycle to the next. The autonomic nervous system transmits - impulses from the central nervous system to peripheral organs and is responsible - for controlling the heart rate, blood pressure and respiratory activity. In - normal individuals, without cardiac disease, the heart rate has a high degree of - beat-to-beat variability. HRV fluctuates with respiration: it increases with - inspiration and decreases with expiration and is primarily mediated by - parasympathetic activity. HRV has been used to evaluate and quantify the cardiac - risk associated with a variety of conditions including cardiac disorders, stroke, - multiple sclerosis and diabetes. In this narrative review, we will examine the - association between HRV and SCD. This report explains the measurement of HRV and - the consequences of reduced HRV in the general population and dialysis patients. - Lastly, this review will outline the possible use of HRV as a clinical predictor - for SCD in the dialysis population. The current understanding of SCD based on HRV - findings among the ESRD population support the use of more aggressive treatment - of CAD; greater use of angiotensin converting enzyme inhibitor - (ACE-i)/angiotensin receptor blockers (ARBs) and beta-blockers and more frequent - and/or nocturnal haemodialysis to improve the survival of a patient with kidney - failure. -FAU - Ranpuria, Reena -AU - Ranpuria R -FAU - Hall, Martica -AU - Hall M -FAU - Chan, Chris T -AU - Chan CT -FAU - Unruh, Mark -AU - Unruh M -LA - eng -GR - DK066006/DK/NIDDK NIH HHS/United States -GR - DK77785/DK/NIDDK NIH HHS/United States -PT - Editorial -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20071114 -PL - England -TA - Nephrol Dial Transplant -JT - Nephrology, dialysis, transplantation : official publication of the European - Dialysis and Transplant Association - European Renal Association -JID - 8706402 -SB - IM -CIN - Nephrol Dial Transplant. 2008 Dec;23(12):4085. doi: 10.1093/ndt/gfn481. PMID: - 18728154 -MH - Death, Sudden, Cardiac/etiology -MH - Heart Function Tests -MH - *Heart Rate -MH - Humans -MH - Kidney Failure, Chronic/complications/*physiopathology/therapy -MH - Renal Dialysis -MH - Risk Factors -RF - 26 -EDAT- 2007/11/16 09:00 -MHDA- 2008/07/17 09:00 -CRDT- 2007/11/16 09:00 -PHST- 2007/11/16 09:00 [pubmed] -PHST- 2008/07/17 09:00 [medline] -PHST- 2007/11/16 09:00 [entrez] -AID - gfm634 [pii] -AID - 10.1093/ndt/gfm634 [doi] -PST - ppublish -SO - Nephrol Dial Transplant. 2008 Feb;23(2):444-9. doi: 10.1093/ndt/gfm634. Epub 2007 - Nov 14. - -PMID- 18718418 -OWN - NLM -STAT- MEDLINE -DCOM- 20081003 -LR - 20220408 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 52 -IP - 9 -DP - 2008 Aug 26 -TI - Air pollution and cardiovascular injury epidemiology, toxicology, and mechanisms. -PG - 719-26 -LID - 10.1016/j.jacc.2008.05.029 [doi] -AB - Recent epidemiologic studies show that increased levels of air pollutants are - positively associated with cardiovascular morbidity and mortality. Inhalation of - air pollutants affects heart rate, heart rate variability, blood pressure, - vascular tone, blood coagulability, and the progression of atherosclerosis. - Several categories within the general population (i.e., people with pre-existing - cardiovascular disease and diabetic and elderly individuals) are considered to be - more susceptible to air pollution-mediated cardiovascular effects. Major - mechanisms of inhalation-mediated cardiovascular toxicity include activation of - pro-inflammatory pathways and generation of reactive oxygen species. Although - most studies focus on the influence of systemic effects, recent studies indicate - that ultrafine particles may be translocated into the circulation and directly - transported to the vasculature and heart where they can induce cardiac - arrhythmias and decrease cardiac contractility and coronary flow. -FAU - Simkhovich, Boris Z -AU - Simkhovich BZ -AD - The Heart Institute, Good Samaritan Hospital, Los Angeles, California, USA. -FAU - Kleinman, Michael T -AU - Kleinman MT -FAU - Kloner, Robert A -AU - Kloner RA -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Air Pollutants) -RN - 0 (Particulate Matter) -SB - IM -MH - Air Pollutants/*pharmacology -MH - Air Pollution/*adverse effects/statistics & numerical data -MH - Cardiovascular Diseases/*epidemiology -MH - Humans -MH - Lung Diseases/epidemiology -MH - Particle Size -MH - Particulate Matter/pharmacology -RF - 95 -EDAT- 2008/08/23 09:00 -MHDA- 2008/10/04 09:00 -CRDT- 2008/08/23 09:00 -PHST- 2008/01/14 00:00 [received] -PHST- 2008/05/14 00:00 [revised] -PHST- 2008/05/19 00:00 [accepted] -PHST- 2008/08/23 09:00 [pubmed] -PHST- 2008/10/04 09:00 [medline] -PHST- 2008/08/23 09:00 [entrez] -AID - S0735-1097(08)01972-4 [pii] -AID - 10.1016/j.jacc.2008.05.029 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2008 Aug 26;52(9):719-26. doi: 10.1016/j.jacc.2008.05.029. - -PMID- 21730830 -OWN - NLM -STAT- MEDLINE -DCOM- 20111221 -LR - 20110811 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 26 -IP - 5 -DP - 2011 Sep -TI - Recent advances in stress echocardiography. -PG - 379-84 -LID - 10.1097/HCO.0b013e328349035b [doi] -AB - PURPOSE OF REVIEW: This article reviews the recent advances in stress - echocardiography, with particular attention to articles published in 2010 and - 2011. It summarizes the developments in the diagnostic and prognostic - capabilities of stress echocardiography, discusses new data regarding the safety - of stress echocardiography, and highlights emerging roles for stress - echocardiography in the areas of left ventricular assist devices, cardiac - transplantation, strain-rate echocardiography, and myocardial perfusion imaging. - RECENT FINDINGS: Stress echocardiography represents a well validated tool in the - diagnosis and assessment of patients with known or suspected coronary artery - disease. Recently, data have emerged supporting the prognostic capabilities of - stress echocardiography in patients with various levels of systolic dysfunction, - diastolic abnormalities, and valvular heart disease. New studies continue to - document the safety of stress echocardiography, particularly with regard to - arrhythmias, neuropsychiatric symptoms, dosing of dobutamine, and intravenous - contrast. Studies are now suggesting that stress echocardiography may play novel - roles in the evaluation of patients with left ventricular assist devices or - potential donors for cardiac transplantation. Technologic developments in - myocardial contrast perfusion imaging, three-dimensional imaging, and strain-rate - echocardiography will continue to advance the field. SUMMARY: Stress - echocardiography represents a dynamic, versatile, and well validated tool for the - noninvasive assessment of patients with a wide spectrum of cardiovascular - diseases. -FAU - Cullen, Michael W -AU - Cullen MW -AD - Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo - Clinic, Rochester, Minnesota 55905, USA. -FAU - Pellikka, Patricia A -AU - Pellikka PA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -SB - IM -MH - Echocardiography, Stress/adverse effects/*trends -MH - Humans -MH - Myocardial Ischemia/*diagnosis -MH - Prognosis -EDAT- 2011/07/07 06:00 -MHDA- 2011/12/22 06:00 -CRDT- 2011/07/07 06:00 -PHST- 2011/07/07 06:00 [entrez] -PHST- 2011/07/07 06:00 [pubmed] -PHST- 2011/12/22 06:00 [medline] -AID - 10.1097/HCO.0b013e328349035b [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2011 Sep;26(5):379-84. doi: 10.1097/HCO.0b013e328349035b. - -PMID- 17479264 -OWN - NLM -STAT- MEDLINE -DCOM- 20070919 -LR - 20181113 -IS - 1619-7070 (Print) -IS - 1619-7070 (Linking) -VI - 34 Suppl 1 -DP - 2007 Jun -TI - Imaging of angiogenesis in cardiology. -PG - S9-19 -AB - In the past decade, there have been major improvements in our understanding of - angiogenesis at the genetic, molecular and cellular levels. Concentrated efforts - in this area have led to new therapeutic approaches to ischaemic heart disease - using angiogenic factors, gene therapy and progenitor cells. Despite very - promising experimental results in animal studies, large clinical trials have - failed to confirm the results in patients with coronary artery disease. Important - questions such as selection of growth factors and donor cells, as well as the - timing, dose and route of administration, have been raised and need to be - answered. Molecular imaging approaches which may provide specific markers of the - angiogenic process (e.g. integrin expression in endothelial cells) have been - introduced and are expected to address some of these questions. Although few - clinical imaging results are currently available, animal studies suggest the - potential role of molecular imaging for characterisation of the angiogenetic - process in vivo and for the monitoring of therapeutic effects. -FAU - Higuchi, Takahiro -AU - Higuchi T -AD - Nuklearmedizinische Klinik und Poliklinik der Technischen Universität München, - Klinikum rechts der Isar, Ismaninger Strasse 22, 81675 Munich, Germany. - higuchi@po2.nsknet.or.jp -FAU - Wester, Hans Juergen -AU - Wester HJ -FAU - Schwaiger, Markus -AU - Schwaiger M -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Germany -TA - Eur J Nucl Med Mol Imaging -JT - European journal of nuclear medicine and molecular imaging -JID - 101140988 -SB - IM -MH - Cardiology/*methods/trends -MH - Diagnostic Imaging/*methods -MH - Diagnostic Techniques, Cardiovascular/trends -MH - Humans -MH - Image Enhancement/*methods -MH - Myocardial Ischemia/complications/*diagnosis -MH - Neovascularization, Pathologic/*diagnosis/etiology -RF - 107 -EDAT- 2007/05/05 09:00 -MHDA- 2007/09/20 09:00 -CRDT- 2007/05/05 09:00 -PHST- 2007/05/05 09:00 [pubmed] -PHST- 2007/09/20 09:00 [medline] -PHST- 2007/05/05 09:00 [entrez] -AID - 10.1007/s00259-007-0436-z [doi] -PST - ppublish -SO - Eur J Nucl Med Mol Imaging. 2007 Jun;34 Suppl 1:S9-19. doi: - 10.1007/s00259-007-0436-z. - -PMID- 17333368 -OWN - NLM -STAT- MEDLINE -DCOM- 20070906 -LR - 20220716 -IS - 1383-875X (Print) -IS - 1383-875X (Linking) -VI - 17 -IP - 3 -DP - 2006 Dec -TI - Are women worldwide under-treated with regard to cardiac resynchronization and - sudden death prevention? -PG - 169-75 -AB - Implantable cardioverter defibrillators (ICDs) have been demonstrated to improve - survival in patients with serious structural heart disease. Likewise, cardiac - resynchronization therapy (CRT) has assumed an important role in the treatment of - patients with symptomatic heart failure because of its demonstrated value in - improving functional class, quality of life, exercise capacity, and survival. - However, these clinical trials have all primarily enrolled Caucasian males, - raising the question as to whether other important subgroups benefit in a - comparable way. Women have lower rates of sudden cardiac death (SCD) compared to - men, and event rates lag 10-20 years behind those in men. Among patients with - known coronary artery disease, women have one-fourth the risk of SCD found in - men. Women with heart failure tend to present at an older age than men, and women - more often have heart failure with preserved systolic function, a group in whom - prophylactic ICD therapy for the prevention of SCD has not been studied. Despite - these differences, analysis of clinical trial results shows that women have - similar outcomes with ICD and CRT therapy compared to men. There is a lower - percentage of women among device therapy patients both in clinical trials and in - practice for reasons that are not clear, but at least some of the difference is - likely due to differences in age at presentation and co-morbidities. In fact, - device therapy overall appears to be under-utilized in both men and women, when - implantation rates are compared to the prevalence of heart failure in the - population as a whole. -FAU - Curtis, Anne B -AU - Curtis AB -AD - Division of Cardiology, University of South Florida, 12901 Bruce B. Downs - Boulevard, MDC 87, Tampa, FL 33612, USA. acurtis@hsc.usf.edu -LA - eng -PT - Journal Article -PT - Review -DEP - 20070228 -PL - Netherlands -TA - J Interv Card Electrophysiol -JT - Journal of interventional cardiac electrophysiology : an international journal of - arrhythmias and pacing -JID - 9708966 -SB - IM -MH - Cardiac Output, Low/*therapy -MH - Clinical Trials as Topic -MH - Death, Sudden, Cardiac/*prevention & control -MH - Defibrillators, Implantable/*statistics & numerical data -MH - Female -MH - Global Health -MH - Humans -MH - Risk Factors -MH - Sex Factors -MH - *Women's Health -RF - 28 -EDAT- 2007/03/03 09:00 -MHDA- 2007/09/07 09:00 -CRDT- 2007/03/03 09:00 -PHST- 2006/11/23 00:00 [received] -PHST- 2006/11/29 00:00 [accepted] -PHST- 2007/03/03 09:00 [pubmed] -PHST- 2007/09/07 09:00 [medline] -PHST- 2007/03/03 09:00 [entrez] -AID - 10.1007/s10840-006-9068-7 [doi] -PST - ppublish -SO - J Interv Card Electrophysiol. 2006 Dec;17(3):169-75. doi: - 10.1007/s10840-006-9068-7. Epub 2007 Feb 28. - -PMID- 20619368 -OWN - NLM -STAT- MEDLINE -DCOM- 20110214 -LR - 20250529 -IS - 1878-7568 (Electronic) -IS - 1742-7061 (Print) -IS - 1742-7061 (Linking) -VI - 7 -IP - 1 -DP - 2011 Jan -TI - Intra-myocardial biomaterial injection therapy in the treatment of heart failure: - Materials, outcomes and challenges. -PG - 1-15 -LID - 10.1016/j.actbio.2010.06.039 [doi] -AB - Heart failure initiated by coronary artery disease and myocardial infarction (MI) - is a widespread, debilitating condition for which there are a limited number of - options to prevent disease progression. Intra-myocardial biomaterial injection - following MI theoretically provides a means to reduce the stresses experienced by - the infarcted ventricular wall, which may alter the pathological remodeling - process in a positive manner. Furthermore, biomaterial injection provides an - opportunity to concurrently introduce cellular components and depots of bioactive - agents. Biologically derived, synthetic and hybrid materials have been applied, - as well as materials designed expressly for this purpose, although optimal design - parameters, including degradation rate and profile, injectability, elastic - modulus and various possible bioactivities, largely remain to be elucidated. This - review seeks to summarize the current body of growing literature where - biomaterial injection, with and without concurrent pharmaceutical or cellular - delivery, has been pursued to improve functional outcomes following MI. The - literature to date generally demonstrates acute functional benefits associated - with biomaterial injection therapy across a broad variety of animal models and - material compositions. Further functional improvements have been reported when - cellular or pharmaceutical agents have been incorporated into the delivery - system. Despite these encouraging early results, the specific mechanisms behind - the observed functional improvements remain to be fully explored and future - studies employing hypothesis-driven material design and selection may increase - the potential of this approach to alleviate the morbidity and mortality of heart - failure. -CI - Copyright © 2010 Acta Materialia Inc. Published by Elsevier Ltd. All rights - reserved. -FAU - Nelson, Devin M -AU - Nelson DM -AD - Department of Bioengineering, University of Pittsburgh, PA 15219, USA. -FAU - Ma, Zuwei -AU - Ma Z -FAU - Fujimoto, Kazuro L -AU - Fujimoto KL -FAU - Hashizume, Ryotaro -AU - Hashizume R -FAU - Wagner, William R -AU - Wagner WR -LA - eng -GR - R01 HL105911/HL/NHLBI NIH HHS/United States -GR - R01 HL069368/HL/NHLBI NIH HHS/United States -GR - T32-HL076124/HL/NHLBI NIH HHS/United States -GR - HL069368/HL/NHLBI NIH HHS/United States -GR - T32 HL076124/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100707 -PL - England -TA - Acta Biomater -JT - Acta biomaterialia -JID - 101233144 -RN - 0 (Biocompatible Materials) -SB - IM -MH - Animals -MH - Biocompatible Materials/*administration & dosage/*therapeutic use -MH - Drug Delivery Systems -MH - Heart Failure/*drug therapy -MH - Humans -MH - Injections -MH - *Materials Testing -MH - Myocardium/*pathology -MH - Treatment Outcome -PMC - PMC3208237 -MID - NIHMS330226 -EDAT- 2010/07/14 06:00 -MHDA- 2011/02/15 06:00 -PMCR- 2012/01/01 -CRDT- 2010/07/13 06:00 -PHST- 2010/05/13 00:00 [received] -PHST- 2010/06/25 00:00 [revised] -PHST- 2010/06/29 00:00 [accepted] -PHST- 2010/07/13 06:00 [entrez] -PHST- 2010/07/14 06:00 [pubmed] -PHST- 2011/02/15 06:00 [medline] -PHST- 2012/01/01 00:00 [pmc-release] -AID - S1742-7061(10)00305-3 [pii] -AID - 10.1016/j.actbio.2010.06.039 [doi] -PST - ppublish -SO - Acta Biomater. 2011 Jan;7(1):1-15. doi: 10.1016/j.actbio.2010.06.039. Epub 2010 - Jul 7. - -PMID- 17130340 -OWN - NLM -STAT- MEDLINE -DCOM- 20070103 -LR - 20061212 -IS - 1524-4539 (Electronic) -IS - 0009-7322 (Linking) -VI - 114 -IP - 24 -DP - 2006 Dec 12 -TI - Cardiovascular risk reduction in high-risk pediatric patients: a scientific - statement from the American Heart Association Expert Panel on Population and - Prevention Science; the Councils on Cardiovascular Disease in the Young, - Epidemiology and Prevention, Nutrition, Physical Activity and Metabolism, High - Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; - and the Interdisciplinary Working Group on Quality of Care and Outcomes Research: - endorsed by the American Academy of Pediatrics. -PG - 2710-38 -AB - Although for most children the process of atherosclerosis is subclinical, - dramatically accelerated atherosclerosis occurs in some pediatric disease states, - with clinical coronary events occurring in childhood and very early adult life. - As with most scientific statements about children and the future risk for - cardiovascular disease, there are no randomized trials documenting the effects of - risk reduction on hard clinical outcomes. A growing body of literature, however, - identifies the importance of premature cardiovascular disease in the course of - certain pediatric diagnoses and addresses the response to risk factor reduction. - For this scientific statement, a panel of experts reviewed what is known about - very premature cardiovascular disease in 8 high-risk pediatric diagnoses and, - from the science base, developed practical recommendations for management of - cardiovascular risk. -FAU - Kavey, Rae-Ellen W -AU - Kavey RE -AD - National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA. -FAU - Allada, Vivek -AU - Allada V -FAU - Daniels, Stephen R -AU - Daniels SR -FAU - Hayman, Laura L -AU - Hayman LL -FAU - McCrindle, Brian W -AU - McCrindle BW -FAU - Newburger, Jane W -AU - Newburger JW -FAU - Parekh, Rulan S -AU - Parekh RS -FAU - Steinberger, Julia -AU - Steinberger J -CN - American Heart Association Expert Panel on Population and Prevention Science -CN - American Heart Association Council on Cardiovascular Disease in the Young -CN - American Heart Association Council on Epidemiology and Prevention -CN - American Heart Association Council on Nutrition, Physical Activity and Metabolism -CN - American Heart Association Council on High Blood Pressure Research -CN - American Heart Association Council on Cardiovascular Nursing -CN - American Heart Association Council on the Kidney in Heart Disease -CN - Interdisciplinary Working Group on Quality of Care and Outcomes Research -LA - eng -PT - Journal Article -PT - Review -DEP - 20061127 -PL - United States -TA - Circulation -JT - Circulation -JID - 0147763 -SB - IM -MH - Arthritis, Rheumatoid/complications -MH - Atherosclerosis/etiology -MH - Cardiovascular Diseases/etiology/*prevention & control -MH - Child -MH - Chronic Disease -MH - Diabetes Complications/prevention & control -MH - Diabetes Mellitus, Type 1/complications -MH - Diabetes Mellitus, Type 2/complications -MH - Evidence-Based Medicine -MH - Heart Defects, Congenital/complications -MH - Heart Transplantation -MH - Humans -MH - Hyperlipoproteinemia Type II/complications/diagnosis/physiopathology/therapy -MH - Kidney Diseases/complications/therapy -MH - Lupus Erythematosus, Systemic/complications -MH - Mucocutaneous Lymph Node Syndrome/complications -MH - Neoplasms/complications -MH - Risk Factors -MH - Risk Reduction Behavior -RF - 401 -EDAT- 2006/11/30 09:00 -MHDA- 2007/01/04 09:00 -CRDT- 2006/11/30 09:00 -PHST- 2006/11/30 09:00 [pubmed] -PHST- 2007/01/04 09:00 [medline] -PHST- 2006/11/30 09:00 [entrez] -AID - CIRCULATIONAHA.106.179568 [pii] -AID - 10.1161/CIRCULATIONAHA.106.179568 [doi] -PST - ppublish -SO - Circulation. 2006 Dec 12;114(24):2710-38. doi: 10.1161/CIRCULATIONAHA.106.179568. - Epub 2006 Nov 27. - -PMID- 23811616 -OWN - NLM -STAT- MEDLINE -DCOM- 20131217 -LR - 20181202 -IS - 1537-7385 (Electronic) -IS - 0894-9115 (Linking) -VI - 92 -IP - 11 -DP - 2013 Nov -TI - Effects of exercise training on endothelial progenitor cells in cardiovascular - disease: a systematic review. -PG - 1020-30 -LID - 10.1097/PHM.0b013e31829b4c4f [doi] -AB - This review aimed to examine the effects of exercise training on mobilization of - endothelial progenitor cells (EPCs) in patients with cardiovascular disease and - to discuss the possible mechanisms involved in the process. A computer-aided - search on PubMed and PEDro was conducted to identify relevant studies published - up to June 2012. Two reviewers independently selected studies for inclusion and - extracted data, namely, quantitative assessment of circulating EPCs. Of the 88 - identified studies, 13 met the inclusion criteria. The 13 studies enrolled 648 - participants, including patients with chronic heart failure, peripheral artery - disease, and coronary artery disease. The exercise characteristics varied largely - across the studies: exercise duration ranged from 2 wks to 6 mos, session - duration ranged from 20 to 60 mins, and exercise intensity was usually calculated - using the maximal heart rate (ranging from 75% to 85%) or the peak/maximum oxygen - consumption (60%-70%). All studies used aerobic exercise. The great majority of - the 13 studies reported significant effects of different exercise regimens on the - number of circulating EPCs. In summary, exercise training seems to increase the - number of circulating EPCs, which could contribute to vascular regeneration and - angiogenesis. These positive effects of chronic exercise seem to be closely - related to the bioavailability of nitric oxide, including increased activity of - endothelial nitric oxide synthase and antioxidant enzymes, and activation of - matrix metalloproteinase 9. -FAU - Ribeiro, Fernando -AU - Ribeiro F -AD - From the CESPU, Polytechnic Health Institute of the North, Grandra (PRD), - Portugal (FR, MdCM); Research Centre in Physical Activity, Health and Leisure - (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal (FR, AJA, NLO, - JO, JAD); Cytogenetics and Genomics Laboratory and CIMAGO, Faculty of Medicine, - University of Coimbra, Coimbra, Portugal (IPR); Higher Institute of Educational - Sciences, Felgueiras, Portugal (AJA); QOPNA, School of Health Sciences, - University of Aveiro, Aveiro, Portugal (FA); and REQUIMTE, Laboratory of - Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of - Porto, Porto, Portugal (FR). -FAU - Ribeiro, Ilda P -AU - Ribeiro IP -FAU - Alves, Alberto J -AU - Alves AJ -FAU - do Céu Monteiro, Maria -AU - do Céu Monteiro M -FAU - Oliveira, Nórton L -AU - Oliveira NL -FAU - Oliveira, José -AU - Oliveira J -FAU - Amado, Francisco -AU - Amado F -FAU - Remião, Fernando -AU - Remião F -FAU - Duarte, José A -AU - Duarte JA -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PT - Systematic Review -PL - United States -TA - Am J Phys Med Rehabil -JT - American journal of physical medicine & rehabilitation -JID - 8803677 -SB - IM -MH - Cardiovascular Diseases/*blood/*physiopathology -MH - Cell Count -MH - Endothelial Cells/*physiology -MH - Exercise/*psychology -MH - Humans -MH - Stem Cells/*physiology -EDAT- 2013/07/03 06:00 -MHDA- 2013/12/18 06:00 -CRDT- 2013/07/02 06:00 -PHST- 2013/07/02 06:00 [entrez] -PHST- 2013/07/03 06:00 [pubmed] -PHST- 2013/12/18 06:00 [medline] -AID - 10.1097/PHM.0b013e31829b4c4f [doi] -PST - ppublish -SO - Am J Phys Med Rehabil. 2013 Nov;92(11):1020-30. doi: - 10.1097/PHM.0b013e31829b4c4f. - -PMID- 18184879 -OWN - NLM -STAT- MEDLINE -DCOM- 20080623 -LR - 20240718 -IS - 1555-905X (Electronic) -IS - 1555-9041 (Print) -IS - 1555-9041 (Linking) -VI - 3 -IP - 2 -DP - 2008 Mar -TI - Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney - disease patient: how do new pieces fit into the uremic puzzle? -PG - 505-21 -LID - 10.2215/CJN.03670807 [doi] -AB - Premature cardiovascular disease (CVD), including stroke, peripheral vascular - disease, sudden death, coronary artery disease, and congestive heart failure, is - a notorious problem in patients with chronic kidney disease (CKD). Because the - presence of CVD is independently associated with kidney function decline, it - appears that the relationship between CKD and CVD is reciprocal or bidirectional, - and that it is this association that leads to the vicious circle contributing to - premature death. As randomized, placebo-controlled trials have so far been - disappointing and unable to show a survival benefit of various treatment - strategies, such a lipid-lowering, increased dialysis dose and normalization of - hemoglobin, the risk factor profile seems to be different in CKD compared with - the general population. Indeed, seemingly paradoxical associations between - traditional risk factors and cardiovascular outcome in patients with advanced CKD - have complicated our efforts to identify the real cardiovascular culprits. This - review focuses on the many new pieces that need to be fit into the complicated - puzzle of uremic vascular disease, including persistent inflammation, endothelial - dysfunction, oxidative stress, and vascular ossification. Each of these is not - only highly prevalent in CKD but also more strongly linked to CVD in these - patients than in the general population. However, a causal relationship between - these new markers and CVD in CKD patients remains to be established. Finally, two - novel disciplines, proteomics and epigenetics, will be discussed, because these - tools may be helpful in the understanding of the discussed vascular risk factors. -FAU - Stenvinkel, Peter -AU - Stenvinkel P -AD - Department of Renal Medicine, K56, Karolinska University Hospital at Huddinge, - 141 86 Stockholm, Sweden. peter.stenvinkel@ki.se -FAU - Carrero, Juan Jesús -AU - Carrero JJ -FAU - Axelsson, Jonas -AU - Axelsson J -FAU - Lindholm, Bengt -AU - Lindholm B -FAU - Heimbürger, Olof -AU - Heimbürger O -FAU - Massy, Ziad -AU - Massy Z -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080109 -PL - United States -TA - Clin J Am Soc Nephrol -JT - Clinical journal of the American Society of Nephrology : CJASN -JID - 101271570 -RN - 63CV1GEK3Y (N,N-dimethylarginine) -RN - 94ZLA3W45F (Arginine) -SB - IM -MH - Albuminuria/complications -MH - Arginine/analogs & derivatives/physiology -MH - Cardiovascular Diseases/*complications/*epidemiology/etiology -MH - Chronic Disease -MH - Endothelium, Vascular/physiopathology -MH - Humans -MH - Kidney Diseases/*complications -MH - Ossification, Heterotopic/complications -MH - Oxidative Stress -MH - Risk Assessment/methods -MH - Uremia/*complications -PMC - PMC6631093 -EDAT- 2008/01/11 09:00 -MHDA- 2008/06/24 09:00 -PMCR- 2009/03/01 -CRDT- 2008/01/11 09:00 -PHST- 2008/01/11 09:00 [pubmed] -PHST- 2008/06/24 09:00 [medline] -PHST- 2008/01/11 09:00 [entrez] -PHST- 2009/03/01 00:00 [pmc-release] -AID - CJN.03670807 [pii] -AID - 03670807 [pii] -AID - 10.2215/CJN.03670807 [doi] -PST - ppublish -SO - Clin J Am Soc Nephrol. 2008 Mar;3(2):505-21. doi: 10.2215/CJN.03670807. Epub 2008 - Jan 9. - -PMID- 20198391 -OWN - NLM -STAT- MEDLINE -DCOM- 20111216 -LR - 20110826 -IS - 1432-5233 (Electronic) -IS - 0940-5429 (Linking) -VI - 48 -IP - 3 -DP - 2011 Sep -TI - The diabetic cardiomyopathy. -PG - 173-81 -LID - 10.1007/s00592-010-0180-x [doi] -AB - Diabetic cardiomyopathy has been defined as "a distinct entity characterized by - the presence of abnormal myocardial performance or structure in the absence of - epicardial coronary artery disease, hypertension, and significant valvular - disease". The diagnosis stems from the detection of myocardial abnormalities and - the exclusion of other contributory causes of cardiomyopathy. It rests on - non-invasive imaging techniques which can demonstrate myocardial dysfunction - across the spectra of clinical presentation. The presence of diabetes is - associated with an increased risk of developing heart failure, and the 75% of - patients with unexplained idiopathic dilated cardiomyopathy were found to be - diabetic. Diabetic patients with microvascular complications show the strongest - association between diabetes and cardiomyopathy, an association that parallels - the duration and severity of hyperglycemia. Metabolic abnormalities (that is - hyperglycemia, hyperinsulinemia, and hyperlipemia) can lead to the cellular - alterations characterizing diabetic cardiomyopathy (that is myocardial fibrosis - and/or myocardial hypertrophy) directly or indirectly (that is by means of - renin-angiotensin system activation, cardiac autonomic neuropathy, alterations in - calcium homeostasis). Moreover, metabolic abnormalities represent, on a clinical - ground, the main therapeutic target in the patients with diabetes since the - diagnosis of diabetes is made. Since diabetic cardiomyopathy is highly prevalent - in the asymptomatic type 2 diabetic patients, screening for its presence at the - earliest stage of development can lead to prevent the progression to chronic - heart failure. The most sensitive test is standard echocardiogram, while a less - expensive pre-screening method is the detection of microalbuminuria. -FAU - Tarquini, Roberto -AU - Tarquini R -AD - Department of Internal Medicine, Azienda Ospedaliero-Universitaria Careggi, - University of Florence, Italy. rtarquini@unifi.it -FAU - Lazzeri, Chiara -AU - Lazzeri C -FAU - Pala, Laura -AU - Pala L -FAU - Rotella, Carlo Maria -AU - Rotella CM -FAU - Gensini, Gian Franco -AU - Gensini GF -LA - eng -PT - Journal Article -PT - Review -DEP - 20100303 -PL - Germany -TA - Acta Diabetol -JT - Acta diabetologica -JID - 9200299 -SB - IM -MH - Animals -MH - Cardiovascular System/physiopathology -MH - Diabetes Mellitus, Type 1/complications/physiopathology -MH - Diabetes Mellitus, Type 2/complications/physiopathology -MH - Diabetic Cardiomyopathies/diagnosis/epidemiology/*etiology -MH - Disease Models, Animal -MH - Humans -EDAT- 2010/03/04 06:00 -MHDA- 2011/12/17 06:00 -CRDT- 2010/03/04 06:00 -PHST- 2009/12/31 00:00 [received] -PHST- 2010/02/11 00:00 [accepted] -PHST- 2010/03/04 06:00 [entrez] -PHST- 2010/03/04 06:00 [pubmed] -PHST- 2011/12/17 06:00 [medline] -AID - 10.1007/s00592-010-0180-x [doi] -PST - ppublish -SO - Acta Diabetol. 2011 Sep;48(3):173-81. doi: 10.1007/s00592-010-0180-x. Epub 2010 - Mar 3. - -PMID- 21572013 -OWN - NLM -STAT- MEDLINE -DCOM- 20110930 -LR - 20211020 -IS - 1522-1539 (Electronic) -IS - 0363-6135 (Print) -IS - 0363-6135 (Linking) -VI - 301 -IP - 2 -DP - 2011 Aug -TI - Doppler velocity measurements from large and small arteries of mice. -PG - H269-78 -LID - 10.1152/ajpheart.00320.2011 [doi] -AB - With the growth of genetic engineering, mice have become increasingly common as - models of human diseases, and this has stimulated the development of techniques - to assess the murine cardiovascular system. Our group has developed nonimaging - and dedicated Doppler techniques for measuring blood velocity in the large and - small peripheral arteries of anesthetized mice. We translated technology - originally designed for human vessels for use in smaller mouse vessels at higher - heart rates by using higher ultrasonic frequencies, smaller transducers, and - higher-speed signal processing. With these methods one can measure cardiac - filling and ejection velocities, velocity pulse arrival times for determining - pulse wave velocity, peripheral blood velocity and vessel wall motion waveforms, - jet velocities for the calculation of the pressure drop across stenoses, and left - main coronary velocity for the estimation of coronary flow reserve. These - noninvasive methods are convenient and easy to apply, but care must be taken in - interpreting measurements due to Doppler sample volume size and angle of - incidence. Doppler methods have been used to characterize and evaluate numerous - cardiovascular phenotypes in mice and have been particularly useful in evaluating - the cardiac and vascular remodeling that occur following transverse aortic - constriction. Although duplex ultrasonic echo-Doppler instruments are being - applied to mice, dedicated Doppler systems are more suitable for some - applications. The magnitudes and waveforms of blood velocities from both cardiac - and peripheral sites are similar in mice and humans, such that much of what is - learned using Doppler technology in mice may be translated back to humans. -FAU - Hartley, Craig J -AU - Hartley CJ -AD - Section of Cardiovascular Research, Department of Medicine, Baylor College of - Medicine, and Methodist DeBakey Heart and Vascular Center, Houston TX, 77030, - USA. chartley@bcm.edu -FAU - Reddy, Anilkumar K -AU - Reddy AK -FAU - Madala, Sridhar -AU - Madala S -FAU - Entman, Mark L -AU - Entman ML -FAU - Michael, Lloyd H -AU - Michael LH -FAU - Taffet, George E -AU - Taffet GE -LA - eng -GR - HL-89792/HL/NHLBI NIH HHS/United States -GR - HL-57068/HL/NHLBI NIH HHS/United States -GR - HL-42267/HL/NHLBI NIH HHS/United States -GR - AG-15568/AG/NIA NIH HHS/United States -GR - R01 HL022512/HL/NHLBI NIH HHS/United States -GR - HL-42313/HL/NHLBI NIH HHS/United States -GR - P41 RR011795/RR/NCRR NIH HHS/United States -GR - HL-52364/HL/NHLBI NIH HHS/United States -GR - P41 EB002182/EB/NIBIB NIH HHS/United States -GR - R01 HL089792/HL/NHLBI NIH HHS/United States -GR - HL-13870/HL/NHLBI NIH HHS/United States -GR - HL-42550/HL/NHLBI NIH HHS/United States -GR - AG-13251/AG/NIA NIH HHS/United States -GR - HL-22512/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20110513 -PL - United States -TA - Am J Physiol Heart Circ Physiol -JT - American journal of physiology. Heart and circulatory physiology -JID - 100901228 -SB - IM -MH - Animals -MH - Arteries/*diagnostic imaging/physiopathology -MH - Blood Flow Velocity -MH - Cardiovascular Diseases/*diagnostic imaging/physiopathology -MH - Disease Models, Animal -MH - Equipment Design -MH - *Hemodynamics -MH - *Laser-Doppler Flowmetry/instrumentation -MH - Mice -MH - Miniaturization -MH - Models, Cardiovascular -MH - Pulsatile Flow -MH - Regional Blood Flow -MH - Transducers, Pressure -MH - *Ultrasonography, Doppler/instrumentation -PMC - PMC3154663 -EDAT- 2011/05/17 06:00 -MHDA- 2011/10/01 06:00 -PMCR- 2012/08/01 -CRDT- 2011/05/17 06:00 -PHST- 2011/05/17 06:00 [entrez] -PHST- 2011/05/17 06:00 [pubmed] -PHST- 2011/10/01 06:00 [medline] -PHST- 2012/08/01 00:00 [pmc-release] -AID - ajpheart.00320.2011 [pii] -AID - H-00320-2011 [pii] -AID - 10.1152/ajpheart.00320.2011 [doi] -PST - ppublish -SO - Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H269-78. doi: - 10.1152/ajpheart.00320.2011. Epub 2011 May 13. - -PMID- 18760848 -OWN - NLM -STAT- MEDLINE -DCOM- 20100824 -LR - 20220413 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 132 -IP - 1 -DP - 2009 Feb 6 -TI - Echocardiographic strain and strain rate imaging--clinical applications. -PG - 11-24 -LID - 10.1016/j.ijcard.2008.06.091 [doi] -AB - Echocardiographic strain and strain rate imaging is a new technology enabling - more reliable and comprehensive assessment of myocardial function. The spectrum - of potential clinical applications is very wide due to its ability to - differentiate between active and passive movement of myocardial segments, to - quantify intraventricular dyssynchrony and to evaluate components of myocardial - function, such as longitudinal myocardial shortening, that are not visually - assessable. The high sensitivity of both tissue Doppler (TDI) derived and - two-dimensional (2D) speckle tracking derived strain and strain rate data for the - early detection of myocardial dysfunction recommend these new non-invasive - diagnostic methods for routine clinical use. In addition to early detection of - myocardial dysfunction of different etiologies, assessment of myocardial - viability, detection of acute allograft rejection after heart transplantation and - early detection of patients with transplant coronary artery disease, strain and - strain rate measurements are helpful in the selection of different therapies and - follow-up evaluations of myocardial function after different medical and surgical - treatment. Strain and strain rate data also provide important prognostic - information. This Review explains the fundamental concepts of strain and strain - rate for both TDI-derived and speckle tracking 2D-strain derived deformation - imaging and discusses the clinical applicability with all the major advantages - and limitations of these new echocardiographic methods, which recently have - become a subject of great interest for clinicians. -FAU - Dandel, Michael -AU - Dandel M -AD - Deutsches Herzzentrum Berlin, Department of Cardiothoracic and Vascular Surgery, - Germany. dandel@dhzb.de -FAU - Hetzer, Roland -AU - Hetzer R -LA - eng -PT - Journal Article -PT - Review -DEP - 20080829 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -SB - IM -MH - Algorithms -MH - Echocardiography, Doppler/instrumentation/*methods -MH - Heart Diseases/*diagnostic imaging/physiopathology -MH - Humans -MH - *Myocardial Contraction -MH - *Myocardium/pathology -MH - Prognosis -MH - *Ventricular Function, Left -RF - 91 -EDAT- 2008/09/02 09:00 -MHDA- 2010/08/25 06:00 -CRDT- 2008/09/02 09:00 -PHST- 2008/04/03 00:00 [received] -PHST- 2008/06/09 00:00 [revised] -PHST- 2008/06/28 00:00 [accepted] -PHST- 2008/09/02 09:00 [pubmed] -PHST- 2010/08/25 06:00 [medline] -PHST- 2008/09/02 09:00 [entrez] -AID - S0167-5273(08)00863-2 [pii] -AID - 10.1016/j.ijcard.2008.06.091 [doi] -PST - ppublish -SO - Int J Cardiol. 2009 Feb 6;132(1):11-24. doi: 10.1016/j.ijcard.2008.06.091. Epub - 2008 Aug 29. - -PMID- 16472143 -OWN - NLM -STAT- MEDLINE -DCOM- 20060314 -LR - 20190728 -IS - 1381-6128 (Print) -IS - 1381-6128 (Linking) -VI - 12 -IP - 4 -DP - 2006 -TI - Does Angiotensin converting enzyme inhibitor protect the heart in cardiac - surgery? From laboratory to operating room: clinical application of experimental - study. -PG - 517-26 -AB - Animal studies have shown angiotensin converting enzyme (ACE) inhibitors to be - effective agents for myocardial protection. They protect against lethal - arrhythmias, preserve ventricular function, improve coronary reserve (especially - after ischemia/reperfusion), and reverse myocardial hypertrophy. Human studies, - on the other hand, have shown inconsistent results. The beneficial effects of ACE - inhibitors demonstrated in animal studies provide major advantages for cardiac - surgery. First, most cardiac surgery is performed under ischemic arrest induced - by a cardioplegic solution, and the protective effects of ACE inhibition against - reperfusion injury can reduce peri-operative mortality and morbidity. Second, - most patients who undergo such surgery have myocardial hypertrophy due to - hypertension, pressure or volume overload mediated by valve disease, or - myocardial infarction. Ventricular hypertrophy is a strong risk factor for sudden - death, probably from arrhythmia. Regression of the hypertrophy may prevent - post-operative sudden death, thereby allowing for long-term benefits of surgery. - In this paper, I review ACE inhibitor studies in animals and humans and the - protective mechanisms involved. I also discuss why human studies show - inconsistent results in spite of the fact that ACE inhibition is consistently - protective in animal studies. Finally, I explore the potential clinical - applications of ACE inhibitors in cardiac surgery. -FAU - Shimada, Yasuyuki -AU - Shimada Y -AD - Department of Cardiovascular Surgery, Yuri Kumiai General Hospital, 38 - Ienoushiro, Aza, Kawaguchi Yuri-Honjo, Akita 015-8511, Japan. - Yasuyuki.Shimada@ma8.seikyou.ne.jp -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Angiotensin-Converting Enzyme Inhibitors/pharmacology/*therapeutic use -MH - Animals -MH - Arrhythmias, Cardiac/prevention & control -MH - *Cardiac Surgical Procedures -MH - Clinical Trials as Topic -MH - Heart Diseases/physiopathology/surgery -MH - Humans -MH - Myocardial Reperfusion Injury/prevention & control -MH - Treatment Outcome -RF - 113 -EDAT- 2006/02/14 09:00 -MHDA- 2006/03/15 09:00 -CRDT- 2006/02/14 09:00 -PHST- 2006/02/14 09:00 [pubmed] -PHST- 2006/03/15 09:00 [medline] -PHST- 2006/02/14 09:00 [entrez] -AID - 10.2174/138161206775474413 [doi] -PST - ppublish -SO - Curr Pharm Des. 2006;12(4):517-26. doi: 10.2174/138161206775474413. - -PMID- 21930186 -OWN - NLM -STAT- MEDLINE -DCOM- 20120808 -LR - 20120201 -IS - 1872-8057 (Electronic) -IS - 0303-7207 (Linking) -VI - 350 -IP - 2 -DP - 2012 Mar 24 -TI - Mechanisms of mineralocorticoid salt-induced hypertension and cardiac fibrosis. -PG - 248-55 -LID - 10.1016/j.mce.2011.09.008 [doi] -AB - For 50 years aldosterone has been thought to act primarily on epithelia to - regulate fluid and electrolyte homeostasis. Mineralocorticoid receptors (MR), - however, are also expressed in nonepithelial tissues such as the heart and - vascular smooth muscle. Recently pathophysiologic effects of nonepithelial MR - activation by aldosterone have been demonstrated, in the context of inappropriate - mineralocorticoid for salt status, including coronary vascular inflammation and - cardiac fibrosis. Consistent with experimental studies, clinical trials (RALES, - EPHESUS), have demonstrated a reduced mortality and morbidity when MR antagonists - are included in the treatment of moderate-severe heart failure. The pathogenesis - of MR-mediated cardiovascular disease is a complex, multifactorial process that - involves loss of vascular reactivity, hypertension, inflammation of the - vasculature and end organs (heart and kidney), oxidative stress and tissue - fibrosis (cardiac and renal). This review will discuss the mechanisms by which - MR, located in the various cell types that comprise the heart, plays a central - role in the development of cardiomyocyte failure, tissue inflammation, - remodelling and hypertension. -CI - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. -FAU - Young, Morag J -AU - Young MJ -AD - Prince Henry's Institute of Medical Research, Department of Physiology, Monash - University, Clayton, VIC 3168, Australia. morag.young@princehenrys.org -FAU - Rickard, Amanda J -AU - Rickard AJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110910 -PL - Ireland -TA - Mol Cell Endocrinol -JT - Molecular and cellular endocrinology -JID - 7500844 -RN - 0 (Receptors, Mineralocorticoid) -RN - 0 (Sodium, Dietary) -SB - IM -MH - Animals -MH - Cardiovascular System/metabolism -MH - Endomyocardial Fibrosis/complications/*genetics/metabolism -MH - Humans -MH - Hypertension/*chemically induced/complications/genetics -MH - Inflammation/genetics/metabolism -MH - Models, Biological -MH - Receptors, Mineralocorticoid/genetics/metabolism/*physiology -MH - Signal Transduction/genetics/physiology -MH - Sodium, Dietary/*adverse effects -EDAT- 2011/09/21 06:00 -MHDA- 2012/08/09 06:00 -CRDT- 2011/09/21 06:00 -PHST- 2011/07/19 00:00 [received] -PHST- 2011/09/01 00:00 [revised] -PHST- 2011/09/04 00:00 [accepted] -PHST- 2011/09/21 06:00 [entrez] -PHST- 2011/09/21 06:00 [pubmed] -PHST- 2012/08/09 06:00 [medline] -AID - S0303-7207(11)00542-9 [pii] -AID - 10.1016/j.mce.2011.09.008 [doi] -PST - ppublish -SO - Mol Cell Endocrinol. 2012 Mar 24;350(2):248-55. doi: 10.1016/j.mce.2011.09.008. - Epub 2011 Sep 10. - -PMID- 18303932 -OWN - NLM -STAT- MEDLINE -DCOM- 20080708 -LR - 20181025 -IS - 1175-3277 (Print) -IS - 1175-3277 (Linking) -VI - 8 -IP - 1 -DP - 2008 -TI - Does sildenafil cause myocardial infarction or sudden cardiac death? -PG - 1-7 -AB - Sildenafil was the first oral compound to be approved for the treatment of - erectile dysfunction. In this paper, we review the current knowledge of the - effects of sildenafil on myocardial infarction and sudden cardiac death. The - first factor we examine is the sexual activity itself. As several studies have - shown, the relative risk for an acute coronary syndrome during intercourse is not - very high. Several studies examining the effects of sildenafil on mortality have - been published during recent years. The great majority of these studies found - that sildenafil is not an extra risk factor for an acute coronary syndrome or - sudden cardiac death. In 1997, the rate of myocardial infarction in men 55-64 - years of age was 1542 per 1,000000 in the US. According to this, the expected - number of deaths as a result of myocardial infarction in patients 55-64 years of - age receiving sildenafil, in the 24-hour period after use, from late March 1997 - to mid November 1998, should have been 52. Instead, the number of reported deaths - were only 15. One very optimistic finding was that sildenafil not only does not - increase mortality, but in fact 'preconditions' the heart and has a - cardioprotective effect. Besides, many studies have shown that sildenafil does - not reduce the exercise tolerance in men with known coronary artery disease. As - far as BP is concerned, the differences before and after the use of sildenafil - are not clinically significant. The only contraindications for sildenafil are - co-administration with alpha-adrenoceptor antagonists or with nitric oxide - donors. According to the most recent studies, isoform 5 of phosphodiesterase has - also been detected in the myocardium and controls the soluble pool of 3', - 5'-cyclic guanosine monophosphate (cGMP). Sildenafil is very specific for cGMP - but it may increase cyclic adenosine monophosphate in the myocardium indirectly. - This does not occur with small therapeutic doses of the drug. There is some - dispute regarding the association of sildenafil with arrhythmias, where the - available evidence is not clear. However, there are suspicions that sildenafil - may cause sympathetic activation. The overall conclusion is that sildenafil is a - safe drug and that its appropriate use does not seem to increase the risk for - myocardial infarction or sudden cardiac death. -FAU - Kontaras, Konstantinos -AU - Kontaras K -AD - 2nd Department of Cardiology, Hellenic Red Cross General Hospital, Athens, - Greece. -FAU - Varnavas, Varnavas -AU - Varnavas V -FAU - Kyriakides, Zenon S -AU - Kyriakides ZS -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -RN - 0 (Phosphodiesterase Inhibitors) -RN - 0 (Piperazines) -RN - 0 (Purines) -RN - 0 (Sulfones) -RN - 0 (Vasodilator Agents) -RN - BW9B0ZE037 (Sildenafil Citrate) -SB - IM -MH - Death, Sudden, Cardiac/*etiology -MH - Erectile Dysfunction/drug therapy -MH - Humans -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/*etiology -MH - Phosphodiesterase Inhibitors/adverse effects/therapeutic use -MH - Piperazines/*adverse effects/therapeutic use -MH - Purines/adverse effects/therapeutic use -MH - Risk -MH - Sildenafil Citrate -MH - Sulfones/*adverse effects/therapeutic use -MH - Vasodilator Agents/*adverse effects/therapeutic use -RF - 50 -EDAT- 2008/02/29 09:00 -MHDA- 2008/07/09 09:00 -CRDT- 2008/02/29 09:00 -PHST- 2008/02/29 09:00 [pubmed] -PHST- 2008/07/09 09:00 [medline] -PHST- 2008/02/29 09:00 [entrez] -AID - 811 [pii] -AID - 10.2165/00129784-200808010-00001 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2008;8(1):1-7. doi: 10.2165/00129784-200808010-00001. - -PMID- 21459259 -OWN - NLM -STAT- MEDLINE -DCOM- 20110607 -LR - 20110404 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 27 -IP - 2 -DP - 2011 Mar-Apr -TI - Smoking cessation and the cardiovascular specialist: Canadian Cardiovascular - Society position paper. -PG - 132-7 -LID - 10.1016/j.cjca.2010.12.060 [doi] -AB - Tobacco addiction is the leading cause of preventable disease, disability, and - death in Canada and is the most significant of the modifiable cardiovascular risk - factors. Tobacco addiction is a principal contributor to the development of - coronary artery disease (CAD) and its consequences, including sudden cardiac - death, acute myocardial infarction, and heart failure. Its prevention and - treatment should be accorded high priority. In fact, 30% of all CAD deaths are - attributable to smoking. The identification and documentation of the smoking - status of all patients, and the provision of cessation assistance, should be a - priority in every cardiovascular setting. Systematic approaches to the - identification and treatment of smokers can dramatically enhance the likelihood - of cessation-the most cost-effective of all the interventions to prevent the - development or progression of CAD. It is the view of the Canadian Cardiovascular - Society that all patients in every medical setting-private office, outpatient - clinic, or hospital-should have their smoking status systematically identified - and documented and be offered specific assistance in initiating a cessation - attempt. The provision of unambiguous, nonjudgemental advice regarding the - importance of cessation and assistance with the initiation of a smoking cessation - attempt should be seen as a fundamental responsibility of any cardiovascular - clinician who encounters smokers in any setting. All cardiovascular specialists - should be familiar with the principles and practice of smoking cessation. It is - important for cardiovascular specialists to be as familiar with the initiation of - smoking-cessation pharmacotherapy as they are with the pharmacological management - of hypertension and hyperlipidemia. -CI - Copyright © 2011. Published by Elsevier Inc. -FAU - Pipe, Andrew L -AU - Pipe AL -AD - University of Ottawa Heart Institute, Ottawa, Ontario, Canada. - apipe@ottawaheart.ca -FAU - Eisenberg, Mark J -AU - Eisenberg MJ -FAU - Gupta, Anil -AU - Gupta A -FAU - Reid, Robert D -AU - Reid RD -FAU - Suskin, Neville G -AU - Suskin NG -FAU - Stone, James A -AU - Stone JA -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -MH - Canada/epidemiology -MH - *Cardiovascular Diseases/epidemiology/etiology/prevention & control -MH - Humans -MH - Morbidity/trends -MH - Risk Assessment/*methods -MH - Smoking/*adverse effects/epidemiology -MH - *Smoking Cessation -EDAT- 2011/04/05 06:00 -MHDA- 2011/06/08 06:00 -CRDT- 2011/04/05 06:00 -PHST- 2011/04/05 06:00 [entrez] -PHST- 2011/04/05 06:00 [pubmed] -PHST- 2011/06/08 06:00 [medline] -AID - S0828-282X(10)00076-0 [pii] -AID - 10.1016/j.cjca.2010.12.060 [doi] -PST - ppublish -SO - Can J Cardiol. 2011 Mar-Apr;27(2):132-7. doi: 10.1016/j.cjca.2010.12.060. - -PMID- 17481562 -OWN - NLM -STAT- MEDLINE -DCOM- 20071012 -LR - 20161124 -IS - 1525-2167 (Print) -IS - 1532-2114 (Linking) -VI - 8 -IP - 3 -DP - 2007 Jun -TI - The clinical applications of contrast echocardiography. -PG - S13-23 -AB - Ultrasound contrast agents are approved for opacification of the heart chambers - and to improve endocardial border definition. The myocardial contrast enhancement - is also very useful for assessing thickening of the myocardium and myocardial - perfusion. Several multicentre and numerous single-centre trials have - demonstrated the usefulness of contrast echocardiography in clinical practice. - Contrast echocardiography is probably one of the best validated echocardiographic - techniques. Improved accuracy of contrast-enhanced images is not restricted to - patients with a poor baseline image quality. Even with an optimal baseline image - quality the borders are not as well defined as after LV opacification. Usage of - contrast can improve image alignment and helps to avoid off-axis scanning. - Contrast studies are particularly useful when a precise measurement of LV - function is needed: 1. To decide about the need of implantable - cardioverter-defibrillators (ICDs), cardiac resynchronization therapy (CRT), 2. - Follow-up of patients with moderate valvular disease and decision for surgical - treatment, 3. Selection and monitoring of patients undergoing chemotherapy with - cardiotoxic drugs, 4. Assessment of LV function in patients in intensive care and - coronary care units. Optimal endocardial border delineation is crucial and often - can be achieved only by ultrasound contrast: 1. Assessment of LV thrombi and - masses, 2. Left ventricular non-compaction/apical hypertrophy, 3. Right - ventricular dysplasia, right ventricular thrombus, 4. Stress echocardiography and - regional wall motion assessment. Future echocardiography will be more 3D and more - quantitative than current echocardiography. And contrast echocardiography has - already proven its value for both applications. -FAU - Olszewski, Robert -AU - Olszewski R -AD - Cardiac Investigation Annexe, Oxford University, John Radcliffe Hospital, Oxford, - UK. -FAU - Timperley, Jon -AU - Timperley J -FAU - Szmigielski, Cezary -AU - Szmigielski C -FAU - Monaghan, Mark -AU - Monaghan M -FAU - Nihoyannopoulos, Petros -AU - Nihoyannopoulos P -FAU - Senior, Roxy -AU - Senior R -FAU - Becher, Harald -AU - Becher H -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Eur J Echocardiogr -JT - European journal of echocardiography : the journal of the Working Group on - Echocardiography of the European Society of Cardiology -JID - 100890618 -RN - 0 (Contrast Media) -SB - IM -EIN - Eur J Echocardiogr. 2007 Oct;8(5):308. Cezary, Szmigielski [corrected to - Szmigielski, Cezary]; Nihoyannopoulis, Petros [corrected to Nihoyannopoulos, - Petros] -MH - Contrast Media -MH - Echocardiography/*methods -MH - Echocardiography, Stress -MH - Heart Ventricles/*diagnostic imaging -MH - Humans -MH - *Stroke Volume -MH - Systole -RF - 55 -EDAT- 2007/05/08 09:00 -MHDA- 2007/10/13 09:00 -CRDT- 2007/05/08 09:00 -PHST- 2007/05/08 09:00 [pubmed] -PHST- 2007/10/13 09:00 [medline] -PHST- 2007/05/08 09:00 [entrez] -AID - S1525-2167(07)00065-0 [pii] -AID - 10.1016/j.euje.2007.03.021 [doi] -PST - ppublish -SO - Eur J Echocardiogr. 2007 Jun;8(3):S13-23. doi: 10.1016/j.euje.2007.03.021. - -PMID- 16449858 -OWN - NLM -STAT- MEDLINE -DCOM- 20060616 -LR - 20191109 -IS - 1741-8267 (Print) -IS - 1741-8267 (Linking) -VI - 13 -IP - 1 -DP - 2006 Feb -TI - The role of complementary and alternative therapies in cardiac rehabilitation: a - systematic evaluation. -PG - 3-9 -AB - BACKGROUND: Presently, complementary and alternative medicine, including both - therapies and herbal/oral supplements, is used globally. Few studies have - examined the use of specific therapies, separate from herbal/oral supplements, in - cardiac rehabilitation. This paper presents a systematic evaluation of current - research evidence related to use of specific complementary and alternative - medicine therapies in secondary prevention of cardiovascular disease, with a view - to making recommendations for cardiac rehabilitation. DESIGN AND METHODS: A - literature search was conducted using complementary and alternative medicine - websites, Medline, Allied and Complementary Medicine, CINAHL, Cochrane databases, - EMBASE, SportDiscus, Clinical Evidence, and Evidence-Based Practice to locate - research-based scientific evidence related to the use of complementary and - alternative medicine in cardiac rehabilitation. Search keywords included heart, - cardiac, cardiovascular, coronary, myocardial and rehabilitation, combined with - particular therapies. Herbal/oral supplements were not included in this - evaluation. RESULTS: Some complementary and alternative medicine therapies may be - useful to patients by themselves or coupled with traditional cardiac - rehabilitation. Tai chi, as a complement to existing exercise interventions, can - be utilized for low and intermediate risk patients. transcendental meditation may - be used as a stress reduction technique. There was insufficient evidence found - for the use of acupuncture or chelation therapy in cardiac rehabilitation or - secondary prevention. CONCLUSIONS: Some complementary and alternative medicine - therapies hold promise for patients in cardiac rehabilitation. Further research - is essential, however, in all areas of complementary and alternative medicine to - confirm its usefulness as an adjunct to cardiac rehabilitation. -FAU - Arthur, Heather M -AU - Arthur HM -AD - Faculty of Health Sciences, McMaster University, Hamilton, Ontario bFaculty of - Medicine, University of Calgary, Alberta, Canada. arthurh@mcmaster.ca -FAU - Patterson, Christine -AU - Patterson C -FAU - Stone, James A -AU - Stone JA -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Eur J Cardiovasc Prev Rehabil -JT - European journal of cardiovascular prevention and rehabilitation : official - journal of the European Society of Cardiology, Working Groups on Epidemiology & - Prevention and Cardiac Rehabilitation and Exercise Physiology -JID - 101192000 -SB - IM -MH - Cardiovascular Diseases/therapy -MH - Chelation Therapy -MH - Clinical Trials as Topic -MH - *Complementary Therapies -MH - Heart Diseases/*rehabilitation -MH - Humans -RF - 32 -EDAT- 2006/02/02 09:00 -MHDA- 2006/06/17 09:00 -CRDT- 2006/02/02 09:00 -PHST- 2006/02/02 09:00 [pubmed] -PHST- 2006/06/17 09:00 [medline] -PHST- 2006/02/02 09:00 [entrez] -AID - 00149831-200602000-00002 [pii] -AID - 10.1097/00149831-200602000-00002 [doi] -PST - ppublish -SO - Eur J Cardiovasc Prev Rehabil. 2006 Feb;13(1):3-9. doi: - 10.1097/00149831-200602000-00002. - -PMID- 19572796 -OWN - NLM -STAT- MEDLINE -DCOM- 20090915 -LR - 20161125 -IS - 1745-2422 (Electronic) -IS - 1743-4440 (Linking) -VI - 6 -IP - 4 -DP - 2009 Jul -TI - Transcatheter aortic valve implantation and potential role of 3D imaging. -PG - 411-21 -LID - 10.1586/erd.09.18 [doi] -AB - Valvular heart disease is a major cause of morbidity and mortality, and - degenerative aortic stenosis has become the most common native valve disorder. - Many patients require eventual aortic valve replacement. For patients not - considered surgical candidates, less invasive transcatheter approaches for valve - replacement/implantation are becoming a viable alternative. The design and - further improvement of transcatheter aortic valve implantation systems is an - elaborate process. 3D imaging is increasingly used for device design because it - allows for quantification of the in vivo anatomy and deformation of the aortic - root. Computed tomography is particularly attractive because it allows fast - acquisition of high-resolution data-sets of the root, including the leaflets and - coronary artery ostia. In this article, we will describe how data from 3D imaging - in the context of transcatheter aortic valve implantation may impact device - design. -FAU - Schoenhagen, Paul -AU - Schoenhagen P -AD - Imaging Institute and Heart and Vascular Institute, Desk J-14, The Cleveland - Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. schoenp1@ccf.org -FAU - Hill, Alexander -AU - Hill A -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Med Devices -JT - Expert review of medical devices -JID - 101230445 -SB - IM -MH - Aortic Valve Stenosis/*diagnostic imaging/*surgery -MH - Cardiac Catheterization/instrumentation/*methods -MH - *Heart Valve Prosthesis -MH - Heart Valve Prosthesis Implantation/*methods -MH - Humans -MH - Imaging, Three-Dimensional/methods -MH - Radiographic Image Interpretation, Computer-Assisted/methods -MH - Surgery, Computer-Assisted/*methods -MH - Tomography, X-Ray Computed/*methods -RF - 127 -EDAT- 2009/07/04 09:00 -MHDA- 2009/09/16 06:00 -CRDT- 2009/07/04 09:00 -PHST- 2009/07/04 09:00 [entrez] -PHST- 2009/07/04 09:00 [pubmed] -PHST- 2009/09/16 06:00 [medline] -AID - 10.1586/erd.09.18 [doi] -PST - ppublish -SO - Expert Rev Med Devices. 2009 Jul;6(4):411-21. doi: 10.1586/erd.09.18. - -PMID- 19301781 -OWN - NLM -STAT- MEDLINE -DCOM- 20091113 -LR - 20191111 -IS - 0034-9887 (Print) -IS - 0034-9887 (Linking) -VI - 136 -IP - 11 -DP - 2008 Nov -TI - [Vascular damage in chronic kidney disease]. -PG - 1476-84 -AB - Cardiovascular disease is a frequent complication of renal failure and is the - most common cause of death in patients with chronic kidney disease (CKD). - Accelerated atherogenesis has been widely documented in CKD and diabetic - nephropathy is the leading cause of renal failure worldwide. Furthermore, CKD - promotes hypertension and dyslipidemia, which in turn may contribute to the - progression of renal failure. All together, hypertension, dyslipidemia and - diabetes are considered major risk factors for the development of endothelial - dysfunction and progression of atherosclerosis. Elevated inflammatory mediators - and activation of the renin-angiotensin system contribute through enhanced - production of reactive oxygen species, to atherogenesis in CKD. Vascular - calcification is also important. Calcification of arteries occurs in the intima - in association with atherosclerosis, where it may contribute to plaque formation, - and in the media, where it causes stiffening. Increased serum levels of - calcification promoters, such as hyperphosphatemia, and a decrease in circulating - and local inhibitors of calcification, favor vascular calcification. On the other - hand, transdifferentiation of vascular smooth muscle cells to osteblast-like - cells would be the pivotal event in calcification. Bone morphogenetic protein - agonists and antagonists are playing a role in this osteogenic differentiation. - Accelerated atherosclerosis and media calcification will then lead to increased - prevalence of coronary artery disease, heart failure, stroke, and peripheral - arterial disease. Prevention and treatment of cardiovascular disease are major - considerations in the management of individuals with CKD. -FAU - Jara, Aquiles -AU - Jara A -AD - Departamento de Nefrología, Escuela de Medicina, Pontificia Universidad Católica - de Chile, Santiago, Chile. -FAU - Mezzano, Sergio -AU - Mezzano S -LA - spa -PT - English Abstract -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -TT - Daño vascular en la enfermedad renal crónica. -PL - Chile -TA - Rev Med Chil -JT - Revista medica de Chile -JID - 0404312 -SB - IM -MH - Calcinosis/etiology/physiopathology -MH - Cardiovascular Diseases/*etiology/physiopathology -MH - Endothelium, Vascular/physiopathology -MH - Humans -MH - Kidney Failure, Chronic/*complications/physiopathology -MH - Risk Factors -RF - 54 -EDAT- 2009/03/24 09:00 -MHDA- 2009/11/17 06:00 -CRDT- 2009/03/24 09:00 -PHST- 2009/03/24 09:00 [entrez] -PHST- 2009/03/24 09:00 [pubmed] -PHST- 2009/11/17 06:00 [medline] -AID - 10.4067/s0034-98872008001100016 [doi] -PST - ppublish -SO - Rev Med Chil. 2008 Nov;136(11):1476-84. doi: 10.4067/s0034-98872008001100016. - -PMID- 19101028 -OWN - NLM -STAT- MEDLINE -DCOM- 20090115 -LR - 20220410 -IS - 1474-547X (Electronic) -IS - 0140-6736 (Linking) -VI - 373 -IP - 9657 -DP - 2009 Jan 3 -TI - Obstructive sleep apnoea and its cardiovascular consequences. -PG - 82-93 -LID - 10.1016/S0140-6736(08)61622-0 [doi] -AB - Obstructive sleep apnoea (OSA) is a common disorder in which repetitive apnoeas - expose the cardiovascular system to cycles of hypoxia, exaggerated negative - intrathoracic pressure, and arousals. These noxious stimuli can, in turn, depress - myocardial contractility, activate the sympathetic nervous system, raise blood - pressure, heart rate, and myocardial wall stress, depress parasympathetic - activity, provoke oxidative stress and systemic inflammation, activate platelets, - and impair vascular endothelial function. Epidemiological studies have shown - significant independent associations between OSA and hypertension, coronary - artery disease, arrhythmias, heart failure, and stroke. In randomised trials, - treating OSA with continuous positive airway pressure lowered blood pressure, - attenuated signs of early atherosclerosis, and, in patients with heart failure, - improved cardiac function. Current data therefore suggest that OSA increases the - risk of developing cardiovascular diseases, and that its treatment has the - potential to diminish such risk. However, large-scale randomised trials are - needed to determine, definitively, whether treating OSA improves cardiovascular - outcomes. -FAU - Bradley, T Douglas -AU - Bradley TD -AD - Sleep Research Laboratory of the Toronto Rehabilitation Institute, Toronto, - Canada. -FAU - Floras, John S -AU - Floras JS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20081226 -PL - England -TA - Lancet -JT - Lancet (London, England) -JID - 2985213R -SB - IM -MH - Cardiovascular Diseases/*etiology -MH - Continuous Positive Airway Pressure -MH - Female -MH - Humans -MH - Male -MH - Polysomnography -MH - Prevalence -MH - Randomized Controlled Trials as Topic -MH - Risk Factors -MH - Sex Distribution -MH - Sleep Apnea, Obstructive/*complications/epidemiology/*physiopathology -RF - 161 -EDAT- 2008/12/23 09:00 -MHDA- 2009/01/16 09:00 -CRDT- 2008/12/23 09:00 -PHST- 2008/12/23 09:00 [entrez] -PHST- 2008/12/23 09:00 [pubmed] -PHST- 2009/01/16 09:00 [medline] -AID - S0140-6736(08)61622-0 [pii] -AID - 10.1016/S0140-6736(08)61622-0 [doi] -PST - ppublish -SO - Lancet. 2009 Jan 3;373(9657):82-93. doi: 10.1016/S0140-6736(08)61622-0. Epub 2008 - Dec 26. - -PMID- 22282894 -OWN - NLM -STAT- MEDLINE -DCOM- 20120522 -LR - 20250626 -IS - 1524-4628 (Electronic) -IS - 0039-2499 (Linking) -VI - 43 -IP - 4 -DP - 2012 Apr -TI - Dual or mono antiplatelet therapy for patients with acute ischemic stroke or - transient ischemic attack: systematic review and meta-analysis of randomized - controlled trials. -PG - 1058-66 -LID - 10.1161/STROKEAHA.111.637686 [doi] -AB - BACKGROUND AND PURPOSE: Antiplatelets are recommended for patients with acute - noncardioembolic stroke or transient ischemic attack. We compared the safety and - efficacy of dual versus mono antiplatelet therapy in patients with acute ischemic - stroke or transient ischemic attack. METHODS: Completed randomized controlled - trials of dual versus mono antiplatelet therapy in patients with acute (≤3 days) - ischemic stroke/transient ischemic attack were identified using electronic - bibliographic searches. The primary outcome was recurrent stroke (ischemic, - hemorrhagic, unknown; fatal, nonfatal). Comparison of binary outcomes between - treatment groups was analyzed with random effect models and described using risk - ratios (95% CI). RESULTS: Twelve completed randomized trials involving 3766 - patients were included. In comparison with mono antiplatelet therapy, dual - therapy (aspirin+dipyridamole and aspirin+clopidogrel) significantly reduced - stroke recurrence, dual 58 (3.3%) versus mono 91 (5.0%; risk ratio, 0.67; 95% CI, - 0.49-0.93); composite vascular event (stroke, myocardial infarction, vascular - death), dual 74 (4.4%) versus mono 106 (6%; risk ratio, 0.75; 95% CI, 0.56-0.99); - and the combination of stroke, transient ischemic attack, acute coronary - syndrome, and all death, dual 100 (1.7%) versus mono 136 (9.1%; risk ratio, 0.71; - 95% CI, 0.56-0.91); dual therapy was also associated with a nonsignificant trend - to increase major bleeding, dual 15 (0.9%) versus mono 6 (0.4%; risk ratio, 2.09; - 95% CI, 0.86-5.06). CONCLUSIONS: Dual antiplatelet therapy appears to be safe and - effective in reducing stroke recurrence and combined vascular events in patients - with acute ischemic stroke or transient ischemic attack as compared with mono - therapy. These results need to be tested in prospective studies. -FAU - Geeganage, Chamila M -AU - Geeganage CM -AD - Division of Stroke, University of Nottingham, City Hospital Campus, Hucknall - Road, Nottingham, NG5 1PB, UK. -FAU - Diener, Hans-Christoph -AU - Diener HC -FAU - Algra, Ale -AU - Algra A -FAU - Chen, Christopher -AU - Chen C -FAU - Topol, Eric J -AU - Topol EJ -FAU - Dengler, Reinhard -AU - Dengler R -FAU - Markus, Hugh S -AU - Markus HS -FAU - Bath, Matthew W -AU - Bath MW -FAU - Bath, Philip M W -AU - Bath PM -CN - Acute Antiplatelet Stroke Trialists Collaboration -LA - eng -GR - 10/104/24/DH_/Department of Health/United Kingdom -GR - PG/08/083/25779/BHF_/British Heart Foundation/United Kingdom -PT - Comparative Study -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -DEP - 20120126 -PL - United States -TA - Stroke -JT - Stroke -JID - 0235266 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 64ALC7F90C (Dipyridamole) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Acute Coronary Syndrome/chemically induced/mortality -MH - Adult -MH - Aged -MH - Aged, 80 and over -MH - Aspirin/*administration & dosage/adverse effects -MH - Brain Ischemia/mortality/*prevention & control -MH - Clopidogrel -MH - Databases, Factual -MH - Dipyridamole/*administration & dosage/adverse effects -MH - Disease-Free Survival -MH - Drug Therapy, Combination -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Platelet Aggregation Inhibitors/*administration & dosage/adverse effects -MH - Randomized Controlled Trials as Topic -MH - Recurrence -MH - Stroke -MH - Survival Rate -MH - Ticlopidine/administration & dosage/adverse effects/*analogs & derivatives -EDAT- 2012/01/28 06:00 -MHDA- 2012/05/23 06:00 -CRDT- 2012/01/28 06:00 -PHST- 2012/01/28 06:00 [entrez] -PHST- 2012/01/28 06:00 [pubmed] -PHST- 2012/05/23 06:00 [medline] -AID - STROKEAHA.111.637686 [pii] -AID - 10.1161/STROKEAHA.111.637686 [doi] -PST - ppublish -SO - Stroke. 2012 Apr;43(4):1058-66. doi: 10.1161/STROKEAHA.111.637686. Epub 2012 Jan - 26. - -PMID- 23410557 -OWN - NLM -STAT- MEDLINE -DCOM- 20130411 -LR - 20130215 -IS - 1555-7162 (Electronic) -IS - 0002-9343 (Linking) -VI - 126 -IP - 3 -DP - 2013 Mar -TI - Phosphodiesterase type 5 inhibitors improve endothelial function and may benefit - cardiovascular conditions. -PG - 192-9 -LID - S0002-9343(12)00832-7 [pii] -LID - 10.1016/j.amjmed.2012.08.015 [doi] -AB - The effects of phosphodiesterase type 5 inhibitors on vasodilation mediated via - nitric oxide-cyclic guanosine monophosphate are well described. Less is known - about other mechanisms through which phosphodiesterase type 5 inhibitors benefit - endothelial function, including normalization of serum biomarkers, increased - levels of endothelial progenitor cells, ischemia-reperfusion protection - mechanisms, and other actions specific to patients with diabetes. These various - mechanisms are reviewed. Their impact on several cardiovascular diseases, - including erectile dysfunction, pulmonary hypertension, heart failure, - high-altitude pulmonary edema, Raynaud's phenomenon, coronary artery disease, - diabetes, and atherosclerosis, is presented. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Schwartz, Bryan G -AU - Schwartz BG -AD - Heart Institute, Good Samaritan Hospital, Los Angeles, Calif 90017-2395, USA. -FAU - Jackson, Graham -AU - Jackson G -FAU - Stecher, Vera J -AU - Stecher VJ -FAU - Campoli-Richards, Deborah M -AU - Campoli-Richards DM -FAU - Kloner, Robert A -AU - Kloner RA -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Am J Med -JT - The American journal of medicine -JID - 0267200 -RN - 0 (Phosphodiesterase 5 Inhibitors) -SB - IM -MH - Cardiovascular Diseases/*drug therapy/physiopathology -MH - Endothelium, Vascular/*drug effects/physiology -MH - Hemodynamics/drug effects/physiology -MH - Humans -MH - Ischemic Preconditioning -MH - Phosphodiesterase 5 Inhibitors/pharmacology/*therapeutic use -MH - Vasodilation/drug effects/physiology -EDAT- 2013/02/16 06:00 -MHDA- 2013/04/12 06:00 -CRDT- 2013/02/16 06:00 -PHST- 2012/07/30 00:00 [received] -PHST- 2012/08/29 00:00 [revised] -PHST- 2012/08/29 00:00 [accepted] -PHST- 2013/02/16 06:00 [entrez] -PHST- 2013/02/16 06:00 [pubmed] -PHST- 2013/04/12 06:00 [medline] -AID - S0002-9343(12)00832-7 [pii] -AID - 10.1016/j.amjmed.2012.08.015 [doi] -PST - ppublish -SO - Am J Med. 2013 Mar;126(3):192-9. doi: 10.1016/j.amjmed.2012.08.015. - -PMID- 18991673 -OWN - NLM -STAT- MEDLINE -DCOM- 20090529 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 14 -IP - 25 -DP - 2008 -TI - Modulation of cardiac metabolism during myocardial ischemia. -PG - 2563-71 -AB - Metabolic modulation during myocardial ischemia is possible by the use of - specific drugs, which may induce a shift from free fatty acid towards - predominantly glucose utilization by the myocardium to increase ATP generation - per unit oxygen consumption. Three agents (trimetazidine, ranolazine, and - perhexiline) have well-documented anti-ischaemic effects. However, perhexiline, - the most potent agent currently available, requires plasma-level monitoring to - avoid hepato-neuro-toxicity. Besides, the long-term safety of trimetazidine and - ranolazine has yet to be established. In addition to their effect in ischemia, - the potential use of these drugs in chronic heart failure is gaining recognition - as clinical and experimental data are showing the improvement of myocardial - function following treatment with several of them, even in the absence of - ischemia. Future applications for this line of treatment is promising and - deserves additional research. In particular, large, randomised, controlled trials - investigating the effects of these agents on mortality and hospitalization rates - due to coronary artery disease are needed. -FAU - Chagas, Antonio C P -AU - Chagas AC -AD - Heart Institute (InCor), University of São Paulo Medical School, São Paulo, - Brazil. antonio.chagas@incor.usp.br -FAU - Dourado, Paulo M M -AU - Dourado PM -FAU - Galvão, Tatiana de Fátima Gonçalves -AU - Galvão Tde F -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Animals -MH - Cardiovascular Agents/pharmacology/therapeutic use -MH - Humans -MH - Ischemic Preconditioning, Myocardial/methods -MH - Myocardial Ischemia/*metabolism/*therapy -MH - Myocardium/*metabolism -RF - 119 -EDAT- 2008/11/11 09:00 -MHDA- 2009/05/30 09:00 -CRDT- 2008/11/11 09:00 -PHST- 2008/11/11 09:00 [pubmed] -PHST- 2009/05/30 09:00 [medline] -PHST- 2008/11/11 09:00 [entrez] -AID - 10.2174/138161208786071236 [doi] -PST - ppublish -SO - Curr Pharm Des. 2008;14(25):2563-71. doi: 10.2174/138161208786071236. - -PMID- 24228077 -OWN - NLM -STAT- MEDLINE -DCOM- 20140407 -LR - 20241219 -IS - 1915-7398 (Electronic) -IS - 1915-7398 (Linking) -VI - 13 -IP - 14 -DP - 2013 -TI - How diet modification challenges are magnified in vulnerable or marginalized - people with diabetes and heart disease: a systematic review and qualitative - meta-synthesis. -PG - 1-40 -AB - BACKGROUND: Diet modification is an important part of self-management for - patients with diabetes and/or heart disease (including coronary artery disease, - heart failure, and atrial fibrillation). Many health care providers and - community-based programs advise lifestyle and diet modification as part of care - for people with these conditions. This report synthesizes qualitative information - on how patients respond differently to the challenges of diet modification. - Qualitative and descriptive evidence can illuminate challenges that may affect - the success and equitable impact of dietary modification interventions. - OBJECTIVES: To (a) examine the diet modification challenges faced by diabetes - and/or heart disease patients; and (b) compare and contrast the challenges faced - by patients who are members of vulnerable and nonvulnerable groups as they change - their diet in response to clinical recommendations. DATA SOURCES: This report - synthesizes 65 primary qualitative studies on the topic of dietary modification - challenges encountered by patients with diabetes and/or heart disease. Included - papers were published between 2002 and 2012 and studied adult patients in North - America, Europe, and Australia/New Zealand. REVIEW METHODS: Qualitative - meta-synthesis was used to integrate findings across primary research studies. - RESULTS: Analysis identified 5 types of challenges that are common to both - vulnerable and nonvulnerable patients: self-discipline, knowledge, coping with - everyday stress, negotiating with family members, and managing the social - significance of food. Vulnerable patients may experience additional barriers, - many of which can magnify or exacerbate those common challenges. LIMITATIONS: - While qualitative insights are robust and often enlightening for understanding - experiences and planning services in other settings, they are not intended to be - generalizable. The findings of the studies reviewed here--and of this - synthesis--do not strictly generalize to the Ontario (or any specific) - population. This evidence must be interpreted and applied carefully, in light of - expertise and the experiences of the relevant community. CONCLUSIONS: Diet - modification is not simply a matter of knowing what to eat and making the - rational choice to change dietary practices. Rather, diet and eating practices - should be considered as part of the situated lives of patients, requiring an - individualized approach that is responsive to the conditions in which each - patient is attempting to make a change. Common challenges include - self-discipline, knowledge, coping with everyday stress, negotiating with family - members, and managing the social significance of food. An individualized approach - is particularly important when working with patients who have vulnerabilities. - PLAIN LANGUAGE SUMMARY: Health care providers often encourage people with - diabetes and/or heart disease to change their diet. They advise people with - diabetes to eat less sugar, starch, and fat. They advise people with heart - disease to eat less fat and salt. However, many patients find it difficult to - change what they eat. This report examines the challenges people may face when - making such changes. It also examines the special challenges faced by people who - are vulnerable due to other factors, such as poverty, lack of education, and - difficulty speaking English. Five themes were common to all people who make diet - changes: self-discipline, knowledge, coping with stress, negotiating with family - members, and managing the social aspect of food. Members of vulnerable groups - also reported other challenges, such as affording fresh fruit and vegetables or - understanding English instructions. This report may help health care providers - work with patients more effectively to make diet changes. -FAU - Vanstone, M -AU - Vanstone M -FAU - Giacomini, M -AU - Giacomini M -FAU - Smith, A -AU - Smith A -FAU - Brundisini, F -AU - Brundisini F -FAU - DeJean, D -AU - DeJean D -FAU - Winsor, S -AU - Winsor S -LA - eng -PT - Journal Article -PT - Review -PT - Systematic Review -DEP - 20130901 -PL - Canada -TA - Ont Health Technol Assess Ser -JT - Ontario health technology assessment series -JID - 101521610 -SB - IM -MH - Adaptation, Psychological -MH - Australasia -MH - Chronic Disease -MH - Diabetes Mellitus/*diet therapy/epidemiology/psychology -MH - Europe -MH - Family Health -MH - Feeding Behavior/ethnology/*psychology -MH - Food Preferences/ethnology/psychology -MH - *Health Knowledge, Attitudes, Practice -MH - Health Status Disparities -MH - Heart Diseases/*diet therapy/epidemiology/psychology -MH - Humans -MH - North America -MH - Qualitative Research -MH - Self Care/methods/*psychology -MH - Social Marginalization -MH - Socioeconomic Factors -MH - Stress, Psychological -MH - Vulnerable Populations/ethnology/*psychology -PMC - PMC3817924 -EDAT- 2013/11/15 06:00 -MHDA- 2014/04/08 06:00 -PMCR- 2013/09/01 -CRDT- 2013/11/15 06:00 -PHST- 2013/11/15 06:00 [entrez] -PHST- 2013/11/15 06:00 [pubmed] -PHST- 2014/04/08 06:00 [medline] -PHST- 2013/09/01 00:00 [pmc-release] -PST - epublish -SO - Ont Health Technol Assess Ser. 2013 Sep 1;13(14):1-40. eCollection 2013. - -PMID- 18453369 -OWN - NLM -STAT- MEDLINE -DCOM- 20080826 -LR - 20220318 -IS - 1546-3222 (Print) -IS - 1546-3222 (Linking) -VI - 5 -IP - 4 -DP - 2008 May 1 -TI - Cardiac disease in chronic obstructive pulmonary disease. -PG - 543-8 -LID - 10.1513/pats.200708-142ET [doi] -AB - The cardiac manifestations of chronic obstructive pulmonary disease (COPD) are - numerous. Impairments of right ventricular dysfunction and pulmonary vascular - disease are well known to complicate the clinical course of COPD and correlate - inversely with survival. The pathogenesis of pulmonary vascular disease in COPD - is likely multifactorial and related to alterations in gas exchange and vascular - biology, as well as structural changes of the pulmonary vasculature and - mechanical factors. Several modalities currently exist for the assessment of - pulmonary vascular disease in COPD, but right heart catheterization remains the - gold standard. Although no specific therapy other than oxygen has been generally - accepted for the treatment of pulmonary hypertension in this population, there - has been renewed interest in specific pulmonary vasodilators. The coexistence of - COPD and coronary artery disease occurs frequently. This association is likely - related to shared risk factors as well as similar pathogenic mechanisms, such as - systemic inflammation. Management strategies for the care of patients with COPD - and coronary artery disease are similar to those without COPD, but care must be - given to address their respiratory limitations. Arrhythmias occur frequently in - patients with COPD, but are rarely fatal and can generally be treated medically. - Use of beta-blockers in the management of cardiac disease, while a theoretical - concern in patients with increased airway resistance, is generally safe with the - use of cardioselective agents. -FAU - Falk, Jeremy A -AU - Falk JA -AD - Division of Pulmonary and Critical Care Medicine, Department of Medicine, - Cedars-Sinai Medical Center, for the David Geffen School of Medicine at UCLA, Los - Angeles, California, USA. falkja@cshs.org -FAU - Kadiev, Steven -AU - Kadiev S -FAU - Criner, Gerard J -AU - Criner GJ -FAU - Scharf, Steven M -AU - Scharf SM -FAU - Minai, Omar A -AU - Minai OA -FAU - Diaz, Philip -AU - Diaz P -LA - eng -GR - N01HR76113/HR/NHLBI NIH HHS/United States -GR - N01HR76107/HR/NHLBI NIH HHS/United States -GR - N01HR76102/HR/NHLBI NIH HHS/United States -GR - N01HR76104/HR/NHLBI NIH HHS/United States -GR - N01HR76118/HR/NHLBI NIH HHS/United States -GR - N01HR76115/HR/NHLBI NIH HHS/United States -GR - N01HR76105/HR/NHLBI NIH HHS/United States -GR - N01HR76111/HR/NHLBI NIH HHS/United States -GR - N01HR76114/HR/NHLBI NIH HHS/United States -GR - N01HR76103/HR/NHLBI NIH HHS/United States -GR - N01HR76110/HR/NHLBI NIH HHS/United States -GR - N01HR76119/HR/NHLBI NIH HHS/United States -GR - N01HR76108/HR/NHLBI NIH HHS/United States -GR - N01HR76106/HR/NHLBI NIH HHS/United States -GR - N01HR76109/HR/NHLBI NIH HHS/United States -GR - N01HR76116/HR/NHLBI NIH HHS/United States -GR - N01HR76112/HR/NHLBI NIH HHS/United States -GR - N01HR76101/HR/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Research Support, U.S. Gov't, P.H.S. -PT - Review -PL - United States -TA - Proc Am Thorac Soc -JT - Proceedings of the American Thoracic Society -JID - 101203596 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Bronchodilator Agents) -RN - 0 (Diuretics) -RN - 0 (Vasodilator Agents) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Bronchodilator Agents/therapeutic use -MH - Cardiac Catheterization -MH - Cardiovascular Diseases/diagnosis/*etiology/physiopathology/*therapy -MH - Diuretics/therapeutic use -MH - Echocardiography -MH - Humans -MH - Natriuretic Peptide, Brain/analysis -MH - Oxygen Inhalation Therapy -MH - Pneumonectomy -MH - Prognosis -MH - Pulmonary Disease, Chronic Obstructive/*complications/physiopathology/therapy -MH - Pulmonary Gas Exchange -MH - Risk Factors -MH - Vasodilator Agents/therapeutic use -PMC - PMC2645333 -EDAT- 2008/05/06 09:00 -MHDA- 2008/08/30 09:00 -PMCR- 2009/05/01 -CRDT- 2008/05/06 09:00 -PHST- 2008/05/06 09:00 [pubmed] -PHST- 2008/08/30 09:00 [medline] -PHST- 2008/05/06 09:00 [entrez] -PHST- 2009/05/01 00:00 [pmc-release] -AID - 5/4/543 [pii] -AID - procats54543 [pii] -AID - 10.1513/pats.200708-142ET [doi] -PST - ppublish -SO - Proc Am Thorac Soc. 2008 May 1;5(4):543-8. doi: 10.1513/pats.200708-142ET. - -PMID- 23224653 -OWN - NLM -STAT- MEDLINE -DCOM- 20130830 -LR - 20161020 -IS - 1573-7241 (Electronic) -IS - 0920-3206 (Linking) -VI - 27 -IP - 2 -DP - 2013 Apr -TI - RAAS inhibitors and cardiovascular protection in large scale trials. -PG - 171-9 -LID - 10.1007/s10557-012-6424-y [doi] -AB - Hypertension, coronary artery disease and heart failure affect over half of the - adult population in most Western societies, and are prime causes of CV morbidity - and mortality. With the ever-increasing worldwide prevalence of CV disease due to - ageing and the "diabetes" pandemic, guideline groups have recognized the - importance of achieving cardioprotection in affected individuals as well as in - those at risk for future CV events. The renin-angiotensin-aldosterone system - (RAAS) is the most important system controlling blood pressure (BP), - cardiovascular and renal function in man. As our understanding of the crucial - role of RAAS in the pathogenesis of most, if not all, CV disease has expanded - over the past decades, so has the development of drugs targeting its individual - components. Angiotensin-converting enzyme inhibitors (ACEi), Ang-II receptor - blockers (ARB), and mineralcorticoid receptor antagonists (MRA) have been - evaluated in large clinical trials for their potential to mediate - cardioprotection, singly or in combination. Direct renin inhibitors are currently - under scrutiny, as well as novel dual-acting RAAS-blocking agents. Herein, we - review the evidence generated from large-scale clinical trials of - cardioprotection achieved through RAAS-blockade. -FAU - von Lueder, Thomas G -AU - von Lueder TG -AD - Department of Epidemiology and Preventive Medicine, Monash Centre of - Cardiovascular Research and Education in Therapeutics, Monash University, Alfred - Hospital, Melbourne, VIC, 3004, Australia. -FAU - Krum, Henry -AU - Krum H -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Cardiovasc Drugs Ther -JT - Cardiovascular drugs and therapy -JID - 8712220 -RN - 0 (Angiotensin Receptor Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Cardiotonic Agents) -RN - EC 3.4.23.15 (Renin) -SB - IM -MH - Angiotensin Receptor Antagonists/pharmacology -MH - Angiotensin-Converting Enzyme Inhibitors/pharmacology -MH - Animals -MH - Cardiotonic Agents/*pharmacology -MH - Cardiovascular Diseases/drug therapy -MH - Humans -MH - Renin/antagonists & inhibitors -MH - Renin-Angiotensin System/*physiology -EDAT- 2012/12/12 06:00 -MHDA- 2013/08/31 06:00 -CRDT- 2012/12/11 06:00 -PHST- 2012/12/11 06:00 [entrez] -PHST- 2012/12/12 06:00 [pubmed] -PHST- 2013/08/31 06:00 [medline] -AID - 10.1007/s10557-012-6424-y [doi] -PST - ppublish -SO - Cardiovasc Drugs Ther. 2013 Apr;27(2):171-9. doi: 10.1007/s10557-012-6424-y. - -PMID- 20605820 -OWN - NLM -STAT- MEDLINE -DCOM- 20100817 -LR - 20181204 -IS - 1931-3543 (Electronic) -IS - 0012-3692 (Linking) -VI - 138 -IP - 1 -DP - 2010 Jul -TI - Acute left ventricular dysfunction in the critically ill. -PG - 198-207 -LID - 10.1378/chest.09-1996 [doi] -AB - Acute left ventricular (LV) dysfunction is common in the critical care setting - and more frequently affects the elderly and patients with comorbidities. Because - of increased mortality and the potential for significant improvement with early - revascularization, the practitioner must first consider acute coronary syndrome. - However, variants of stress (takotsubo) cardiomyopathy may be more prevalent in - ICU settings than previously recognized. Early diagnosis is important to direct - treatment of complications of stress cardiomyopathy, such as dynamic LV outflow - tract obstruction, heart failure, and arrhythmias. Global LV dysfunction occurs - in the critically ill because of the cardio-depressant effect of inflammatory - mediators and endotoxins in septic shock as well as direct catecholamine - toxicity. Tachycardia, hypertension, and severe metabolic abnormalities can - independently cause global LV dysfunction, which typically improves with - addressing the precipitating factor. Routine troponin testing may help early - detection of cardiac injury and biomarkers could have prognostic value - independent of prior cardiac disease. Echocardiography is ideally suited to - quantify LV dysfunction and determine its most likely cause. LV dysfunction - suggests a worse prognosis, but with appropriate therapy outcomes can be - optimized. -FAU - Chockalingam, Anand -AU - Chockalingam A -AD - Division of Cardiovascular Medicine, Department of Internal Medicine, University - of Missouri School of Medicine, MO, USA. chockalingama@health.missouri.edu -FAU - Mehra, Ankit -AU - Mehra A -FAU - Dorairajan, Smrita -AU - Dorairajan S -FAU - Dellsperger, Kevin C -AU - Dellsperger KC -LA - eng -PT - Journal Article -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - United States -TA - Chest -JT - Chest -JID - 0231335 -RN - 0 (Biomarkers) -SB - IM -MH - Acute Disease -MH - Biomarkers/blood -MH - Cardiac Catheterization -MH - *Critical Illness -MH - Disease Progression -MH - Echocardiography -MH - Humans -MH - Incidence -MH - Inpatients -MH - Intensive Care Units -MH - Severity of Illness Index -MH - Survival Rate -MH - *Ventricular Dysfunction, Left/diagnosis/epidemiology/physiopathology -RF - 75 -EDAT- 2010/07/08 06:00 -MHDA- 2010/08/18 06:00 -CRDT- 2010/07/08 06:00 -PHST- 2010/07/08 06:00 [entrez] -PHST- 2010/07/08 06:00 [pubmed] -PHST- 2010/08/18 06:00 [medline] -AID - S0012-3692(10)60368-6 [pii] -AID - 10.1378/chest.09-1996 [doi] -PST - ppublish -SO - Chest. 2010 Jul;138(1):198-207. doi: 10.1378/chest.09-1996. - -PMID- 20308745 -OWN - NLM -STAT- MEDLINE -DCOM- 20100928 -LR - 20130418 -IS - 0971-5916 (Print) -IS - 0971-5916 (Linking) -VI - 131 -DP - 2010 Feb -TI - Cardiovascular consequences of obstructive sleep apnoea. -PG - 196-205 -AB - Obstructive sleep apnoea (OSA) is a form of sleep disordered breathing with a - high prevalence rate and is often underdiagnosed. OSA is associated with - hypertension, coronary artery disease, stroke, peripheral vascular disease, heart - failure, and arrhythmias. The presence of OSA may be a strong predictor of fatal - cardiovascular events in patients with cardiovascular disease (CVD). Increased - sympathetic drive, activation of metabolic and inflammatory markers, and impaired - vascular function are some of the proposed mechanisms that could explain the - association between OSA and cardiovascular diseases. Understanding these - mechanisms is important for identifying treatment strategies. The presence of OSA - should be considered in clinical practice, especially in patients with CVD. - Randomized intervention studies are needed to establish whether early - identification and treatment of OSA patients reduces cardiovascular morbidity. -FAU - Kuniyoshi, Fatima H Sert -AU - Kuniyoshi FH -AD - Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic - & Foundation, Rochester, MN, USA. -FAU - Pusalavidyasagar, Snigdha -AU - Pusalavidyasagar S -FAU - Singh, Prachi -AU - Singh P -FAU - Somers, Virend K -AU - Somers VK -LA - eng -GR - HL65176/HL/NHLBI NIH HHS/United States -GR - M01-RR00585/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - India -TA - Indian J Med Res -JT - The Indian journal of medical research -JID - 0374701 -SB - IM -MH - Cardiovascular Diseases/*complications/*etiology -MH - Continuous Positive Airway Pressure -MH - Endothelium, Vascular/pathology -MH - Female -MH - Humans -MH - Hypertension, Pulmonary/pathology -MH - Inflammation -MH - Male -MH - Myocardial Ischemia/pathology -MH - Research Design -MH - Sleep -MH - Sleep Apnea, Obstructive/*diagnosis/*etiology -MH - Stroke -MH - Sympathetic Nervous System -MH - Weight Loss -RF - 119 -EDAT- 2010/03/24 06:00 -MHDA- 2010/09/30 06:00 -CRDT- 2010/03/24 06:00 -PHST- 2010/03/24 06:00 [entrez] -PHST- 2010/03/24 06:00 [pubmed] -PHST- 2010/09/30 06:00 [medline] -PST - ppublish -SO - Indian J Med Res. 2010 Feb;131:196-205. - -PMID- 20407743 -OWN - NLM -STAT- MEDLINE -DCOM- 20100927 -LR - 20220318 -IS - 1432-0428 (Electronic) -IS - 0012-186X (Linking) -VI - 53 -IP - 8 -DP - 2010 Aug -TI - The case for hypoglycaemia as a proarrhythmic event: basic and clinical evidence. -PG - 1552-61 -LID - 10.1007/s00125-010-1752-6 [doi] -AB - Recent clinical studies show that hypoglycaemia is associated with increased risk - of death, especially in patients with coronary artery disease or acute myocardial - infarction. This paper reviews data from cellular and clinical research - supporting the hypothesis that acute hypoglycaemia increases the risk of - malignant ventricular arrhythmias and death in patients with diabetes by - generating the two classic abnormalities responsible for the proarrhythmic effect - of medications, i.e. QT prolongation and Ca(2+) overload. Acute hypoglycaemia - causes QT prolongation and the risk of ventricular tachycardia by directly - suppressing K(+) currents activated during repolarisation, a proarrhythmic effect - of many medications. Since diabetes itself, myocardial infarction, hypertrophy, - autonomic neuropathy and congestive heart failure also cause QT prolongation, the - arrhythmogenic effect of hypoglycaemia is likely to be greatest in patients with - pre-existent cardiac disease and diabetes. Furthermore, the catecholamine surge - during hypoglycaemia raises intracellular Ca(2+), thereby increasing the risk of - ventricular tachycardia and fibrillation by the same mechanism as that activated - by sympathomimetic inotropic agents and digoxin. Diabetes itself may sensitise - myocardium to the arrhythmogenic effect of Ca(2+) overload. In humans, - noradrenaline (norepinephrine) also lengthens action potential duration and - causes further QT prolongation. Finally, both hypoglycaemia and the catecholamine - response acutely lower serum K(+), which leads to QT prolongation and Ca(2+) - loading. Thus, hypoglycaemia and the subsequent catecholamine surge provoke - multiple, interactive, synergistic responses that are known to be proarrhythmic - when associated with medications and other electrolyte abnormalities. Patients - with diabetes and pre-existing cardiac disease may therefore have increased risk - of ventricular tachycardia and fibrillation during hypoglycaemic episodes. -FAU - Nordin, C -AU - Nordin C -AD - Division of Cardiology, Montefiore Medical Center, 111 E. 210th Street, Bronx, NY - 10467, USA. charles.nordin@einstein.yu.edu -LA - eng -PT - Journal Article -PT - Review -DEP - 20100421 -PL - Germany -TA - Diabetologia -JT - Diabetologia -JID - 0006777 -SB - IM -MH - Arrhythmias, Cardiac/*etiology/physiopathology -MH - Diabetes Mellitus/*physiopathology -MH - Humans -MH - Hypoglycemia/*complications/physiopathology -MH - Risk -MH - Risk Factors -RF - 99 -EDAT- 2010/04/22 06:00 -MHDA- 2010/09/29 06:00 -CRDT- 2010/04/22 06:00 -PHST- 2009/07/20 00:00 [received] -PHST- 2010/02/03 00:00 [accepted] -PHST- 2010/04/22 06:00 [entrez] -PHST- 2010/04/22 06:00 [pubmed] -PHST- 2010/09/29 06:00 [medline] -AID - 10.1007/s00125-010-1752-6 [doi] -PST - ppublish -SO - Diabetologia. 2010 Aug;53(8):1552-61. doi: 10.1007/s00125-010-1752-6. Epub 2010 - Apr 21. - -PMID- 18649821 -OWN - NLM -STAT- MEDLINE -DCOM- 20080919 -LR - 20190907 -IS - 0098-9134 (Print) -IS - 0098-9134 (Linking) -VI - 34 -IP - 7 -DP - 2008 Jul -TI - Atrial fibrillation among older adults: pathophysiology, symptoms, and treatment. -PG - 26-33; quiz 34-5 -AB - Atrial fibrillation is the most common arrhythmia among older adults. Valvular - heart disease, dilated cardiomyopathy, aortic stenosis, hypertension, coronary - artery disease, pericarditis, thyrotoxicosis, pulmonary disease, cardiac surgery, - alcohol excess, and alcohol withdrawal are associated with atrial fibrillation. - Nurses caring for older adults need to understand the condition's - pathophysiology, signs and symptoms, diagnostic data and treatment protocols, and - adherence issues to prevent the formation of emboli in chronic atrial - fibrillation and to understand treatment of this common arrhythmia. This article - presents an individual example of an elderly man exhibiting a new onset of atrial - fibrillation and the interventions required to manage the associated - complications. Atrial fibrillation places patients at risk for stroke from a - thromboembolism; thus, pharmacological and nonpharmocological care strategies for - managing patients with atrial fibrillation are discussed. -FAU - Hardin, Sonya R -AU - Hardin SR -AD - School of Nursing, University of North Carolina at Charlotte, Charlotte, NC - 28223, USA. srhardin@uncc.edu -FAU - Steele, James R -AU - Steele JR -LA - eng -GR - T32 NR07091/NR/NINR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - J Gerontol Nurs -JT - Journal of gerontological nursing -JID - 7510258 -RN - 0 (Anti-Arrhythmia Agents) -CIN - J Gerontol Nurs. 2008 Oct;34(10):7; author reply 7. doi: - 10.3928/00989134-20081001-04. PMID: 18942533 -MH - Aged -MH - Anti-Arrhythmia Agents/therapeutic use -MH - Atrial Fibrillation/classification/diagnosis/etiology/*therapy -MH - Catheter Ablation -MH - Electric Countershock -MH - Geriatric Assessment -MH - Geriatric Nursing/*organization & administration -MH - Health Services Needs and Demand -MH - Humans -MH - Long-Term Care -MH - Male -MH - *Nurse's Role -MH - Nursing Assessment -MH - Patient Care Planning/*organization & administration -MH - Risk Assessment -MH - Risk Factors -MH - Thromboembolism/etiology/prevention & control -RF - 28 -EDAT- 2008/07/25 09:00 -MHDA- 2008/09/20 09:00 -CRDT- 2008/07/25 09:00 -PHST- 2008/07/25 09:00 [pubmed] -PHST- 2008/09/20 09:00 [medline] -PHST- 2008/07/25 09:00 [entrez] -AID - 10.3928/00989134-20080701-04 [doi] -PST - ppublish -SO - J Gerontol Nurs. 2008 Jul;34(7):26-33; quiz 34-5. doi: - 10.3928/00989134-20080701-04. - -PMID- 18361324 -OWN - NLM -STAT- MEDLINE -DCOM- 20080522 -LR - 20151119 -IS - 1426-9686 (Print) -IS - 1426-9686 (Linking) -VI - 23 -IP - 137 -DP - 2007 Nov -TI - [Diagnostic and prognostic value of cardiac troponins in patients with chronic - kidney disease]. -PG - 375-81 -AB - In the contemporary diagnostics of myocardial infarction importance of the role - of biochemical markers such as troponins, CK, CK-MB, CK-MB mass has been - underscored. In the paper biochemical aspects of their composition and the - kinetics of troponin realase by the heart have been presented. Frequent - occurrence of cardiovascular diseases in population of patients with chronic - kidney disease, being the results of coexistence of traditional and - non-traditional risk factors, has been highlighted. Also, difficulties in - diagnostics of acute coronary symptoms in this group of patients have been - pointed to. In the article the factors leading to non- specific elevation of - serum troponin levels in this patient population, as well as the influence of the - degree of kidney function impairment and influence of the type of dialysis on - troponin levels have been discussed. Based on the analysis of the major clinical - trials the role of troponin in diagnostics of myocardial infarction and long-term - prognosis in patients with chronic kidney disease have been discussed. Other - clinical conditions in which serum troponin level elevation is observed have been - although discussed. -FAU - Marcinkowska, Elzbieta -AU - Marcinkowska E -AD - Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum w Bydgoszczy, Katedra - i Klinika Nefrologii, Nadciśnienia Tetniczego i Chorób Wewnetrznych. - nerka@nerka.cpro.pl -FAU - Flisiński, Mariusz -AU - Flisiński M -FAU - Manitius, Jacek -AU - Manitius J -LA - pol -PT - English Abstract -PT - Journal Article -PT - Review -TT - Znaczenie diagnostyczne i prognostyczne troponin w przewlekłej chorobie nerek. -PL - Poland -TA - Pol Merkur Lekarski -JT - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego -JID - 9705469 -RN - 0 (Biomarkers) -RN - 0 (Troponin) -RN - EC 2.7.3.2 (Creatine Kinase, MB Form) -SB - IM -MH - Biomarkers/blood -MH - Creatine Kinase, MB Form/blood -MH - Humans -MH - Kidney Failure, Chronic/*blood/*diagnosis -MH - Prognosis -MH - Troponin/*blood -RF - 56 -EDAT- 2008/03/26 09:00 -MHDA- 2008/05/23 09:00 -CRDT- 2008/03/26 09:00 -PHST- 2008/03/26 09:00 [pubmed] -PHST- 2008/05/23 09:00 [medline] -PHST- 2008/03/26 09:00 [entrez] -PST - ppublish -SO - Pol Merkur Lekarski. 2007 Nov;23(137):375-81. - -PMID- 23594423 -OWN - NLM -STAT- MEDLINE -DCOM- 20140123 -LR - 20130521 -IS - 1421-9786 (Electronic) -IS - 1015-9770 (Linking) -VI - 35 -IP - 4 -DP - 2013 -TI - Train the vessel, gain the brain: physical activity and vessel function and the - impact on stroke prevention and outcome in cerebrovascular disease. -PG - 303-12 -LID - 10.1159/000347061 [doi] -AB - The burden of cerebrovascular disease (CVD) is huge and therapeutic options are - limited. Physical activity is effective in preventing coronary heart and - peripheral artery disease both experimentally and clinically. It is likely that - the protective effects of exercise can be extended to both CVD and cognitive - impairment. The pleiotropic protective and preventive mechanisms induced by - physical activity include increased perfusion as well as mechanisms of collateral - recruitment and neovascularization mediated by arterio- and angiogenesis. - Physical activity increases the bioavailability of nitric oxide, bone - marrow-derived CD34+ cells and growth factors, all of which promote - neovascularization. Additionally, shear stress is discussed as a potential - mechanism for vessel growth. Moreover, physical activity plays a role in - endothelial function and cerebral autoregulation in small- and large-artery CVD. - The vascular niche hypothesis highlights the complex interactions of neuro- and - angiogenesis for regenerative and repair mechanisms in the human brain. - Experimental and clinical studies demonstrate the positive impact of prior - physical activity on stroke lesion size and on outcome after stroke. Clinical - trials are necessary to further address the impact of physical activity on - primary and secondary stroke prevention, outcome and cognitive function. -CI - Copyright © 2013 S. Karger AG, Basel. -FAU - Schmidt, Wolf -AU - Schmidt W -AD - Center for Stroke Research Berlin (CSB), Charité University Medicine Berlin, - Berlin, Germany. wolf.schmidt@charite.de -FAU - Endres, Matthias -AU - Endres M -FAU - Dimeo, Fernando -AU - Dimeo F -FAU - Jungehulsing, Gerhard J -AU - Jungehulsing GJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130410 -PL - Switzerland -TA - Cerebrovasc Dis -JT - Cerebrovascular diseases (Basel, Switzerland) -JID - 9100851 -SB - IM -MH - Animals -MH - Brain/*blood supply/pathology/physiopathology -MH - Cerebral Arteries/*physiopathology -MH - *Cerebrovascular Circulation -MH - Cognition -MH - Collateral Circulation -MH - *Exercise -MH - Humans -MH - *Motor Activity -MH - Neovascularization, Physiologic -MH - Primary Prevention/*methods -MH - Risk Factors -MH - Risk Reduction Behavior -MH - Stroke/diagnosis/etiology/physiopathology/*prevention & control/psychology -MH - Treatment Outcome -EDAT- 2013/04/19 06:00 -MHDA- 2014/01/24 06:00 -CRDT- 2013/04/19 06:00 -PHST- 2012/10/11 00:00 [received] -PHST- 2013/01/02 00:00 [accepted] -PHST- 2013/04/19 06:00 [entrez] -PHST- 2013/04/19 06:00 [pubmed] -PHST- 2014/01/24 06:00 [medline] -AID - 000347061 [pii] -AID - 10.1159/000347061 [doi] -PST - ppublish -SO - Cerebrovasc Dis. 2013;35(4):303-12. doi: 10.1159/000347061. Epub 2013 Apr 10. - -PMID- 20148368 -OWN - NLM -STAT- MEDLINE -DCOM- 20101112 -LR - 20211020 -IS - 1970-9366 (Electronic) -IS - 1828-0447 (Linking) -VI - 5 -IP - 4 -DP - 2010 Aug -TI - Combined oral anticoagulants and antiplatelets: benefits and risks. -PG - 281-90 -LID - 10.1007/s11739-010-0349-x [doi] -AB - Combined antiplatelet and anticoagulant therapy has been suggested for those - clinical conditions in which conventional antithrombotic regimens have shown - suboptimal efficacy, and in patients with indication for both: antiplatelet and - anticoagulant therapy. Clinical trials aimed at assessing the clinical benefit of - the association with respect to mono-therapy have been conducted in patients with - atrial fibrillation, in patients with recent myocardial infarction, and in - patients with prosthetic heart valves. Overall, a favorable benefit-risk profile - of combined therapy in comparison to anticoagulant alone has been observed in - patients with mechanical prosthetic heart valves and in those with coronary - artery disease while no clear advantage has been shown in patients with atrial - fibrillation. In almost all these studies, however, a higher risk of major - bleeding has been observed in patients receiving combined therapy in comparison - to patients receiving warfarin alone. Thus, a combined regimen of anticoagulant - and antiplatelet therapy should be reserved for selected patients at high risk of - thromboembolic events who have a low risk of bleeding. -FAU - Vedovati, Maria Cristina -AU - Vedovati MC -AD - Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, - Perugia, Italy. mcristinaved@yahoo.it -FAU - Becattini, Cecilia -AU - Becattini C -FAU - Agnelli, Giancarlo -AU - Agnelli G -LA - eng -PT - Journal Article -PT - Review -DEP - 20100211 -PL - Italy -TA - Intern Emerg Med -JT - Internal and emergency medicine -JID - 101263418 -RN - 0 (Anticoagulants) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -CIN - Intern Emerg Med. 2010 Aug;5(4):275-6. doi: 10.1007/s11739-010-0418-1. PMID: - 20574756 -MH - Anticoagulants/administration & dosage/*adverse effects -MH - Drug Therapy, Combination/*adverse effects -MH - Emergency Medical Services -MH - Humans -MH - Platelet Aggregation Inhibitors/administration & dosage/*adverse effects -MH - Risk Assessment -EDAT- 2010/02/12 06:00 -MHDA- 2010/11/13 06:00 -CRDT- 2010/02/12 06:00 -PHST- 2009/10/10 00:00 [received] -PHST- 2009/11/23 00:00 [accepted] -PHST- 2010/02/12 06:00 [entrez] -PHST- 2010/02/12 06:00 [pubmed] -PHST- 2010/11/13 06:00 [medline] -AID - 10.1007/s11739-010-0349-x [doi] -PST - ppublish -SO - Intern Emerg Med. 2010 Aug;5(4):281-90. doi: 10.1007/s11739-010-0349-x. Epub 2010 - Feb 11. - -PMID- 18174638 -OWN - NLM -STAT- MEDLINE -DCOM- 20080715 -LR - 20220211 -IS - 0019-5359 (Print) -IS - 0019-5359 (Linking) -VI - 61 -IP - 12 -DP - 2007 Dec -TI - Novel phosphodiesterase-5 inhibitors: current indications and future directions. -PG - 667-79 -AB - Cardiovascular diseases like hypertension, hyperlipidemia, diabetes mellitus and - obesity are the important predictors of erectile dysfunction (ED). Endothelial - dysfunction is proposed to be the underlying cause of ED, just like coronary - artery disease. Sildenafil was originally developed to treat angina pectoris but - later on was recognized as novel treatment option for impotence. To date, - sildenafil has been the most extensively studied PDE (phosphodiesterase)-5 - inhibitor. Currently two more PDE-5 inhibitors, tadalafil and vardenafil, are - under study. Newer compounds have certain advantages over sildenafil, including - greater selectivity for PDE-5 compared with other isoenzymes, absence of effect - of food on absorption, faster onset and longer duration of action. PDE-5 - inhibitors are emerging as novel therapeutic tools with a potential to protect or - enhance endothelial function in humans and to selectively improve regional blood - flow. The FDA has recently approved a reformulation of sildenafil for the - treatment of pulmonary arterial hypertension. Raynaud's phenomenon, respiratory - disorders with ventilation/ perfusion mismatch, congestive cardiac failure, - hypertension and stroke are the other conditions in which PDE-5 inhibitors are - being tried. It is hoped that this group of drugs will soon emerge as a novel - weapon in the armamentarium against various cardiovascular and pulmonary - diseases. -FAU - Sharma, Rashmi -AU - Sharma R -AD - Department of Pharmacology and Therapeutics, Govt. Medical College, Jammu, J and - K, India. rashmichams@yahoo.com -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian J Med Sci -JT - Indian journal of medical sciences -JID - 0373023 -RN - 0 (Phosphodiesterase 5 Inhibitors) -SB - IM -MH - Cardiovascular Diseases/chemically induced -MH - Clinical Trials as Topic -MH - Counseling -MH - Erectile Dysfunction/drug therapy -MH - Forecasting -MH - Heart Failure/drug therapy -MH - Humans -MH - Hypertension, Pulmonary/drug therapy -MH - Male -MH - *Phosphodiesterase 5 Inhibitors -RF - 45 -EDAT- 2008/01/05 09:00 -MHDA- 2008/07/17 09:00 -CRDT- 2008/01/05 09:00 -PHST- 2008/01/05 09:00 [pubmed] -PHST- 2008/07/17 09:00 [medline] -PHST- 2008/01/05 09:00 [entrez] -PST - ppublish -SO - Indian J Med Sci. 2007 Dec;61(12):667-79. - -PMID- 20536467 -OWN - NLM -STAT- MEDLINE -DCOM- 20100701 -LR - 20161125 -IS - 1749-6632 (Electronic) -IS - 0077-8923 (Linking) -VI - 1194 -DP - 2010 Apr -TI - Thymosin beta4: structure, function, and biological properties supporting current - and future clinical applications. -PG - 179-89 -LID - 10.1111/j.1749-6632.2010.05492.x [doi] -AB - Published studies have described a number of physiological properties and - cellular functions of thymosin beta4 (Tbeta4), the major G-actin-sequestering - molecule in mammalian cells. Those activities include the promotion of cell - migration, blood vessel formation, cell survival, stem cell differentiation, the - modulation of cytokines, chemokines, and specific proteases, the upregulation of - matrix molecules and gene expression, and the downregulation of a major nuclear - transcription factor. Such properties have provided the scientific rationale for - a number of ongoing and planned dermal, corneal, cardiac clinical trials - evaluating the tissue protective, regenerative and repair potential of Tbeta4, - and direction for future clinical applications in the treatment of diseases of - the central nervous system, lung inflammatory disease, and sepsis. A special - emphasis is placed on the development of Tbeta4 in the treatment of patients with - ST elevation myocardial infarction in combination with percutaneous coronary - intervention. -FAU - Crockford, David -AU - Crockford D -AD - RegeneRx Biopharmaceuticals Inc., Rockville, Maryland, USA. - dcrockford@regenerx.com -FAU - Turjman, Nabila -AU - Turjman N -FAU - Allan, Christian -AU - Allan C -FAU - Angel, Janet -AU - Angel J -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Ann N Y Acad Sci -JT - Annals of the New York Academy of Sciences -JID - 7506858 -RN - 0 (Actins) -RN - 0 (Chemokines) -RN - 549LM7U24W (thymosin beta(4)) -RN - 61512-21-8 (Thymosin) -SB - IM -MH - Actins/genetics/*metabolism/physiology -MH - Animals -MH - Cell Movement/genetics/*physiology -MH - Cell Nucleus/genetics/metabolism/physiology -MH - Cell Survival/genetics/physiology -MH - Chemokines/genetics/metabolism/physiology -MH - Down-Regulation -MH - Heart/physiology -MH - Humans -MH - Mice -MH - *Thymosin/chemistry/metabolism/physiology -MH - Up-Regulation -MH - Wound Healing/genetics/*physiology -RF - 57 -EDAT- 2010/06/12 06:00 -MHDA- 2010/07/02 06:00 -CRDT- 2010/06/12 06:00 -PHST- 2010/06/12 06:00 [entrez] -PHST- 2010/06/12 06:00 [pubmed] -PHST- 2010/07/02 06:00 [medline] -AID - NYAS5492 [pii] -AID - 10.1111/j.1749-6632.2010.05492.x [doi] -PST - ppublish -SO - Ann N Y Acad Sci. 2010 Apr;1194:179-89. doi: 10.1111/j.1749-6632.2010.05492.x. - -PMID- 17539693 -OWN - NLM -STAT- MEDLINE -DCOM- 20071022 -LR - 20241219 -IS - 1555-2101 (Electronic) -IS - 0160-6689 (Linking) -VI - 68 Suppl 4 -DP - 2007 -TI - Increasing global burden of cardiovascular disease in general populations and - patients with schizophrenia. -PG - 4-7 -AB - Cardiovascular disease (CVD), which includes coronary heart, cerebrovascular, and - peripheral vascular disease, is the leading cause of death in the United States - and most developed countries, accounting for about 50% of all deaths. The major - risk factors include obesity and its consequences, dyslipidemia, hypertension, - insulin resistance leading to diabetes, and cigarette smoking. In developing - countries, CVD will become the leading cause of death due to alarming increases - in obesity, sedentary lifestyles, cigarette smoking, and improvements in - prevention and treatment of malnutrition and infection. Compared with - nonschizophrenics, patients with schizophrenia have a 20% shorter life expectancy - (i.e., from 76 to 61 years). In general populations, about 1% die from suicide - compared with about 10% among patients with schizophrenia (relative risk = 10). - For CVD, the corresponding figures are 50% and about 75% (relative risk = 1.5). - In patients with schizophrenia, however, CVD occurs more frequently and accounts - for more premature deaths than suicide. Patients with schizophrenia have - alarmingly higher rates of obesity, dyslipidemia, hypertension, diabetes, and - cigarette smoking than nonschizophrenic individuals in the general population. - Compounding these data, patients with schizophrenia have less access to medical - care, consume less medical care, and are less compliant. Primary prevention - strategies should include the choice of antipsychotic drug regimens that do not - adversely affect the major risk factors for CVD. -FAU - Hennekens, Charles H -AU - Hennekens CH -AD - Department of Biomedical Sciences, Center of Excellence, Florida Atlantic - University, Boca Raton; Nova Southeastern University, Fort Lauderdale; and - University of Miami Miller School of Medicine, Miami, Fla, USA. - profchhmd@prodigy.net -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Clin Psychiatry -JT - The Journal of clinical psychiatry -JID - 7801243 -SB - IM -MH - Cardiovascular Diseases/*complications/economics -MH - *Cost of Illness -MH - Developing Countries -MH - Humans -MH - Metabolic Syndrome -MH - Risk Factors -MH - Schizophrenia/*complications/economics -RF - 27 -EDAT- 2007/08/19 09:00 -MHDA- 2007/10/24 09:00 -CRDT- 2007/08/19 09:00 -PHST- 2007/08/19 09:00 [pubmed] -PHST- 2007/10/24 09:00 [medline] -PHST- 2007/08/19 09:00 [entrez] -PST - ppublish -SO - J Clin Psychiatry. 2007;68 Suppl 4:4-7. - -PMID- 23647842 -OWN - NLM -STAT- MEDLINE -DCOM- 20140131 -LR - 20130529 -IS - 1879-0828 (Electronic) -IS - 0953-6205 (Linking) -VI - 24 -IP - 4 -DP - 2013 Jun -TI - Air particulate matter and cardiovascular disease: a narrative review. -PG - 295-302 -LID - S0953-6205(13)00104-0 [pii] -LID - 10.1016/j.ejim.2013.04.001 [doi] -AB - Consistent evidences from both epidemiological and experimental studies have - demonstrated that short- and long-term exposure to particulate matter (PM), in - particular to the finest particles (i.e. airborne PM with aerodynamic diameter - less than 2.5 μm, PM2.5), is associated with cardiovascular morbidity and - mortality. PM concentration has been linked with several clinical manifestations - of cardiovascular diseases (CVD), including myocardial infarction, stroke, heart - failure, arrhythmias, and venous thromboembolism. Noteworthy, some groups of - subjects, like elderly, diabetics, or those with known coronary artery disease, - appear specifically susceptible to the harmful effects triggered by PM exposure. - Although the PM-related risk for a single individual appears relatively low, the - PM-related population attributable risk is impressive. Recent studies indicate - that the PM-CVD relationship is likely more complex than a mere quantitative - association between overall PM concentration and disease risk. Indeed, the - biological effects of PM may vary in function of both the aerodynamic diameter - and the chemical composition. Moreover, it has been shown that the influence of - air pollution on health is not limited to PM. Indeed, other gaseous pollutants - may play an independent role in CVD, suggesting the need to develop - multi-pollutant preventive approaches. Causality has been recently strongly - supported by observations showing reduced CVD mortality after coordinated - community policies resulting in lowering PM exposure at population level. An - in-depth knowledge on the heterogeneous sources, chemical compounds, and - biological effects of PM may help to propose more accurate and clinically - effective recommendations for this important and modifiable factor contributing - to CVD burden. -CI - Copyright © 2013 European Federation of Internal Medicine. Published by Elsevier - B.V. All rights reserved. -FAU - Martinelli, Nicola -AU - Martinelli N -AD - Department of Medicine, Section of Internal Medicine B, University of Verona, - Italy. nicola.martinelli@univr.it -FAU - Olivieri, Oliviero -AU - Olivieri O -FAU - Girelli, Domenico -AU - Girelli D -LA - eng -PT - Journal Article -PT - Review -DEP - 20130504 -PL - Netherlands -TA - Eur J Intern Med -JT - European journal of internal medicine -JID - 9003220 -RN - 0 (Air Pollutants) -RN - 0 (Particulate Matter) -SB - IM -MH - Air Pollutants/*adverse effects -MH - Cardiovascular Diseases/epidemiology/*etiology -MH - Environmental Exposure/*adverse effects -MH - Humans -MH - Particulate Matter/*adverse effects/chemistry/metabolism -EDAT- 2013/05/08 06:00 -MHDA- 2014/02/01 06:00 -CRDT- 2013/05/08 06:00 -PHST- 2013/02/01 00:00 [received] -PHST- 2013/04/03 00:00 [revised] -PHST- 2013/04/05 00:00 [accepted] -PHST- 2013/05/08 06:00 [entrez] -PHST- 2013/05/08 06:00 [pubmed] -PHST- 2014/02/01 06:00 [medline] -AID - S0953-6205(13)00104-0 [pii] -AID - 10.1016/j.ejim.2013.04.001 [doi] -PST - ppublish -SO - Eur J Intern Med. 2013 Jun;24(4):295-302. doi: 10.1016/j.ejim.2013.04.001. Epub - 2013 May 4. - -PMID- 19920359 -OWN - NLM -STAT- MEDLINE -DCOM- 20100426 -LR - 20241105 -IS - 1347-4820 (Electronic) -IS - 1346-9843 (Linking) -VI - 74 -IP - 1 -DP - 2010 Jan -TI - Non-invasive vascular function tests: their pathophysiological background and - clinical application. -PG - 24-33 -AB - The arterial wall has 3 layers (ie, the intima, including the endothelium, the - media, and the adventitia); each of these layers has individual roles in systemic - circulation. The vascular endothelium regulates the vascular tone, hemostasis - and/or vascular permeability, and the media is the major determinant of arterial - elasticity, which regulates the conduit function (delivery of blood to tissues) - and cushioning effect (for generation of continuous blood flow). Failure of these - functions results in organ/vascular damage. Several non-invasive methods are - currently used to assess vascular dysfunction, including measurement of - flow-mediated vasodilatation of the brachial artery induced by reactive hyperemia - (FMD), pulse wave velocity (PWV), the augmentation index (AI), and central blood - pressure. Endothelial dysfunction, which is assessed by FMD, contributes to the - initiation/progression of atherosclerosis. Increased arterial stiffness, which is - assessed by the PWV and/or AI, causes increased cardiac afterload, impaired - coronary arterial blood supply, atherogenesis and/or microvascular damage. The - combination of risk stratification by assessment of conventional risk factors for - cardiovascular disease (CVD) with not only a morphological assessment of vascular - damage, such as carotid ultrasound examination, but also vascular function tests, - may be a useful strategy for the management of CVD and its related risk factors. - (Circ J 2010; 74: 24 - 33). -FAU - Tomiyama, Hirofumi -AU - Tomiyama H -AD - Second Department of Internal Medicine, Tokyo Medical University, Japan. - tomiyama@tokyo-med.ac.jp -FAU - Yamashina, Akira -AU - Yamashina A -LA - eng -PT - Journal Article -PT - Review -DEP - 20091117 -PL - Japan -TA - Circ J -JT - Circulation journal : official journal of the Japanese Circulation Society -JID - 101137683 -SB - IM -MH - Blood Flow Velocity/physiology -MH - Blood Pressure/physiology -MH - Brachial Artery/physiology -MH - Cardiovascular System/*physiopathology -MH - Heart Function Tests/*methods -MH - Humans -MH - Vasodilation/physiology -RF - 94 -EDAT- 2009/11/19 06:00 -MHDA- 2010/04/27 06:00 -CRDT- 2009/11/19 06:00 -PHST- 2009/11/19 06:00 [entrez] -PHST- 2009/11/19 06:00 [pubmed] -PHST- 2010/04/27 06:00 [medline] -AID - JST.JSTAGE/circj/CJ-09-0534 [pii] -AID - 10.1253/circj.cj-09-0534 [doi] -PST - ppublish -SO - Circ J. 2010 Jan;74(1):24-33. doi: 10.1253/circj.cj-09-0534. Epub 2009 Nov 17. - -PMID- 21104219 -OWN - NLM -STAT- MEDLINE -DCOM- 20110504 -LR - 20211020 -IS - 1432-1289 (Electronic) -IS - 0020-9554 (Linking) -VI - 51 -IP - 12 -DP - 2010 Dec -TI - [Transcatheter valve interventions for heart valve diseases]. -PG - 1480-91 -LID - 10.1007/s00108-010-2718-y [doi] -AB - Severe aortic stenosis is a significant source of morbidity and mortality among - the aging population. Due to prohibitive surgical risk, many patients are not - candidates for surgery. Therefore, transcatheter aortic valve implantation has - emerged as a promising technology for treating this group of high risk patients. - With increasing experience, this procedure can be performed successfully and - safely in selected high risk patients. Nevertheless, before widespread use and - application to lower risk patients the results of randomized studies are - mandatory. Primary (degenerative) and secondary (functional) mitral regurgitation - (MR) is an important cause of heart failure. The double orifice technique of - mitral valve repair using the MitraClip® system is one of many transcatheter - approaches to treat significant MR in patients at high risk for conventional - surgery. This technique is effective in reducing MR severity in patients - suffering from both degenerative and functional MR. Percutaneous pulmonary valve - implantation (PPVI) is an interventional treatment for adolescents and young - adults with congenital heart disease. After corrective or palliative operation in - infancy or early childhood, some patients regularly need reoperations for right - ventricular outflow tract reconstruction. In the last decade, PPVI has evolved as - an alternative treatment option with much less morbidity compared to repeated - surgery. -FAU - Schaefer, A -AU - Schaefer A -AD - Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, - Carl-Neuberg-Straße 1, Hannover, Germany. schaefer.arnd@mh-hannover.de -FAU - Bertram, H -AU - Bertram H -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Kathetergestützte Therapie von Herzklappenfehlern. -PL - Germany -TA - Internist (Berl) -JT - Der Internist -JID - 0264620 -SB - IM -MH - Adolescent -MH - Adult -MH - Aged -MH - Aortic Valve Stenosis/surgery -MH - Bioprosthesis -MH - Cardiac Catheterization/*instrumentation/methods -MH - Coronary Vessels -MH - Heart Defects, Congenital/surgery -MH - Heart Valve Diseases/*surgery -MH - Heart Valve Prosthesis Implantation/*instrumentation/methods -MH - Humans -MH - Infant -MH - Mitral Valve Insufficiency/surgery -MH - Postoperative Complications/etiology -MH - Prosthesis Design -MH - Randomized Controlled Trials as Topic -MH - Reoperation -MH - Stents -MH - Ventricular Outflow Obstruction/surgery -MH - Young Adult -EDAT- 2010/11/26 06:00 -MHDA- 2011/05/05 06:00 -CRDT- 2010/11/25 06:00 -PHST- 2010/11/25 06:00 [entrez] -PHST- 2010/11/26 06:00 [pubmed] -PHST- 2011/05/05 06:00 [medline] -AID - 10.1007/s00108-010-2718-y [doi] -PST - ppublish -SO - Internist (Berl). 2010 Dec;51(12):1480-91. doi: 10.1007/s00108-010-2718-y. - -PMID- 20617412 -OWN - NLM -STAT- MEDLINE -DCOM- 20110621 -LR - 20211020 -IS - 1534-3170 (Electronic) -IS - 1523-3782 (Linking) -VI - 12 -IP - 5 -DP - 2010 Sep -TI - Percutaneous mitral valve interventions: overview of new approaches. -PG - 404-12 -LID - 10.1007/s11886-010-0130-9 [doi] -AB - The percutaneous management of valvular heart disease has recently been receiving - a great deal of interest as an area of great potential. Innovative technologies - are now being developed to treat mitral regurgitation. Although there are - established surgical techniques for treating organic mitral regurgitation, the - surgical management of functional mitral regurgitation remains controversial, and - such patients have a poor prognosis. Therefore, a percutaneous treatment for - functional mitral regurgitation holds great clinical potential. Having a - nonsurgical approach available may be attractive to patients with organic mitral - valve regurgitation as well. Several approaches and devices have been designed to - treat specifically functional mitral regurgitation, and some of these have been - applied to humans in early-stage evaluations. The MitraClip device (Abbott - Laboratories, Abbott Park, IL) has been used to treat both functional and - degenerative mitral valve regurgitation and has been compared to surgery in the - EVEREST II (Endovascular Valve Edge-to-Edge Repair Study II) randomized trial. - Although the field of percutaneous management of mitral regurgitation is at an - early stage, it has been demonstrated that percutaneous approaches can reduce - mitral regurgitation, suggesting there is a great deal of potential for clinical - benefit to patients with mitral regurgitation. -FAU - Goldberg, Steven L -AU - Goldberg SL -AD - University of Washington Medical Center, Seattle, WA, USA. - stevgold@u.washington.edu -FAU - Feldman, Ted -AU - Feldman T -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -SB - IM -MH - Coronary Sinus -MH - Echocardiography -MH - Echocardiography, Doppler, Color -MH - Fluoroscopy -MH - Heart Valve Diseases/diagnostic imaging/pathology/surgery/*therapy -MH - Heart Valve Prosthesis Implantation/instrumentation/*methods -MH - Humans -MH - Mitral Valve/diagnostic imaging/*pathology/surgery -MH - Mitral Valve Insufficiency/diagnostic imaging/pathology/surgery/*therapy -MH - Prognosis -MH - Risk Assessment -MH - Stroke Volume -MH - Ventricular Function, Left -EDAT- 2010/07/10 06:00 -MHDA- 2011/06/22 06:00 -CRDT- 2010/07/10 06:00 -PHST- 2010/07/10 06:00 [entrez] -PHST- 2010/07/10 06:00 [pubmed] -PHST- 2011/06/22 06:00 [medline] -AID - 10.1007/s11886-010-0130-9 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2010 Sep;12(5):404-12. doi: 10.1007/s11886-010-0130-9. - -PMID- 21087422 -OWN - NLM -STAT- MEDLINE -DCOM- 20110304 -LR - 20110505 -IS - 1747-0803 (Electronic) -IS - 1747-079X (Linking) -VI - 5 -IP - 5 -DP - 2010 Sep-Oct -TI - Left ventricular non compaction in children. -PG - 384-97 -LID - 10.1111/j.1747-0803.2010.00446.x [doi] -AB - Left ventricular non compaction (LVNC) is a myocardial disease characterized by a - hypertrabeculated myocardium. The hypertrabeculations in the left ventricular - wall define deep recesses communicating with the left ventricular chamber where - blood penetrates with increased risk of blood clots in the meshwork of the - prominent trabeculations. The left ventricular apex and the free wall are - particularly affected. During in utero ventriculogenesis, myocardial blood supply - is initially linked to the presence of sinusoids, in which blood penetrates and - diffuses nutriments and oxygen to myocardial cells. Progressively, with the - development of the heart and the increase of cells demand of blood, coronary - arteries system develops. This step is associated with myocardial modification - that leads to compaction of hypertrabeculated myocardial net. Probably, the - premature interruption of this process leads to ventricular noncompaction. Many - studies have been conducted in adults with hypertrabeculated myocardium. To date, - data regarding childhood LVNC are sparse. The aim of this review is to summarize - the clinical and preclinical knowledge about LVNC in children. -FAU - Weisz, Sara H -AU - Weisz SH -AD - Department of Cardiology, Second University of Naples, Monaldi Hospital, Naples, - Italy. -FAU - Limongelli, Giuseppe -AU - Limongelli G -FAU - Pacileo, Giuseppe -AU - Pacileo G -FAU - Calabro, Paolo -AU - Calabro P -FAU - Russo, Maria G -AU - Russo MG -FAU - Calabro, Raffaele -AU - Calabro R -FAU - Vatta, Matteo -AU - Vatta M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Congenit Heart Dis -JT - Congenital heart disease -JID - 101256510 -SB - IM -MH - Adolescent -MH - Child -MH - Child, Preschool -MH - Disease Progression -MH - Genetic Predisposition to Disease -MH - Humans -MH - Infant -MH - Infant, Newborn -MH - *Isolated Noncompaction of the Ventricular - Myocardium/diagnosis/embryology/genetics/physiopathology/therapy -MH - Phenotype -MH - Predictive Value of Tests -MH - Treatment Outcome -MH - Ventricular Function, Left -MH - Young Adult -EDAT- 2010/11/23 06:00 -MHDA- 2011/03/05 06:00 -CRDT- 2010/11/20 06:00 -PHST- 2010/11/20 06:00 [entrez] -PHST- 2010/11/23 06:00 [pubmed] -PHST- 2011/03/05 06:00 [medline] -AID - CHD446 [pii] -AID - 10.1111/j.1747-0803.2010.00446.x [doi] -PST - ppublish -SO - Congenit Heart Dis. 2010 Sep-Oct;5(5):384-97. doi: - 10.1111/j.1747-0803.2010.00446.x. - -PMID- 17873567 -OWN - NLM -STAT- MEDLINE -DCOM- 20071129 -LR - 20191210 -IS - 0887-9303 (Print) -IS - 0887-9303 (Linking) -VI - 30 -IP - 4 -DP - 2007 Oct-Dec -TI - Management strategies to meet the core heart failure measures for acute - decompensated heart failure: a nursing perspective. -PG - 307-20 -AB - Despite enormous advances in the medical management of heart disease, heart - failure (HF) persists as a leading cause of hospitalization in our elderly. In - 2001, the American Heart Association and the American College of Cardiology - published Guidelines for Secondary Prevention for Patients With Coronary and - Other Atherosclerotic Vascular Disease. The guidelines proactively responded to a - growing body of evidence confirming that comprehensive risk factor management and - risk reduction improve quality of life and survival, while reducing recurrent - cardiovascular events. In spite of the well-crafted, comprehensive HF guidelines, - morbidity, mortality, and hospital readmission rates for acute decompensated - heart failure remain high, and adherence to HF guidelines is not always optimal. - The Joint Commission has implemented a number of quality care performance - indicators based on the Guidelines for Secondary Prevention; among them are the - Core HF Measures for hospitalized HF patients. The Core HF Measures are endorsed - by the Center for Medicare and Medicaid and has been adopted as a national - benchmark for measurement and public reporting of healthcare performance and for - Medicare payments (Joint Commission). The implementation and monitoring of Core - HF Measures has prioritized attention toward patient education and risk factor - modification to prevent future hospitalization. Critical care nurses are on the - frontline to champion uptake and adherence of Core HF Measures. The purpose of - this article is to highlight the critical component that nursing care, guided by - the Core HF Measures, can offer to improve the quality of patient care in acute - decompensated heart failure. -FAU - Gardetto, Nancy J -AU - Gardetto NJ -AD - Department of Nursing and Patient Care Services, San Diego Veterans Affairs - Medical Center, VA San Diego Healthcare System, La Jolla, California 92161, USA. - gardetto.nancy@va.gov -FAU - Carroll, Karen C -AU - Carroll KC -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Nurs Q -JT - Critical care nursing quarterly -JID - 8704517 -MH - Acute Disease -MH - Aged -MH - American Heart Association -MH - Benchmarking/organization & administration -MH - Cardiology -MH - Centers for Medicare and Medicaid Services, U.S. -MH - Critical Care/*organization & administration -MH - Evidence-Based Medicine -MH - Guideline Adherence -MH - Heart Failure/epidemiology/etiology/*nursing -MH - Hospitalization/statistics & numerical data -MH - Humans -MH - Joint Commission on Accreditation of Healthcare Organizations -MH - *Nurse's Role -MH - Patient Discharge -MH - Patient Education as Topic -MH - Patient Readmission/statistics & numerical data -MH - *Practice Guidelines as Topic -MH - Quality Indicators, Health Care/*organization & administration -MH - Quality of Life -MH - Risk Reduction Behavior -MH - Societies, Medical -MH - Survival Rate -MH - United States/epidemiology -RF - 24 -EDAT- 2007/09/18 09:00 -MHDA- 2007/12/06 09:00 -CRDT- 2007/09/18 09:00 -PHST- 2007/09/18 09:00 [pubmed] -PHST- 2007/12/06 09:00 [medline] -PHST- 2007/09/18 09:00 [entrez] -AID - 00002727-200710000-00005 [pii] -AID - 10.1097/01.CNQ.0000290364.57677.56 [doi] -PST - ppublish -SO - Crit Care Nurs Q. 2007 Oct-Dec;30(4):307-20. doi: - 10.1097/01.CNQ.0000290364.57677.56. - -PMID- 22872132 -OWN - NLM -STAT- MEDLINE -DCOM- 20130516 -LR - 20131121 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 27 -IP - 5 -DP - 2012 Sep -TI - Is a cardioprotective action of alcohol a myth? -PG - 550-5 -LID - 10.1097/HCO.0b013e328356dc30 [doi] -AB - PURPOSE OF REVIEW: Numerous epidemiological studies have demonstrated that light - to moderate alcohol consumption is associated with reduced risk of cardiovascular - disease (CVD). The purpose of this review is to discuss the potential CV benefit - of alcohol consumption with a particular focus on the findings of publications - appearing within the past 2 years. RECENT FINDINGS: Results of observational - studies and meta-analyses are largely concordant in suggesting the possibility of - a beneficial effect of alcohol on CVD via several mechanisms, including actions - on lipid metabolism and hemostatic factors. There are, however, studies that do - not find the classic U-shaped association between alcohol consumption and CVD. - Recent data suggest that the findings of coronary protection by alcohol - consumption may be partly due to misclassification and confounding factors. - Drinking patterns appear to be important factors to take into account when - interpreting the results of epidemiological studies. SUMMARY: No data are - currently available to directly support a causal relationship between alcohol - intake and CVD. As well-conducted randomized studies assessing the causal role of - alcohol in cardioprotection are not feasible, future epidemiological studies - evaluating the relationship between alcohol and CVD should carefully choose the - covariates in any multivariate analysis. It remains premature to promote alcohol - consumption as a basis for CV protection. -FAU - Hansel, Boris -AU - Hansel B -AD - Service d'Endocrinologie-Métabolisme, AP-HP, France. boris.hansel@psl.aphp.fr -FAU - Kontush, Anatol -AU - Kontush A -FAU - Bruckert, Eric -AU - Bruckert E -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -RN - 0 (Cardiotonic Agents) -RN - 3K9958V90M (Ethanol) -SB - IM -MH - *Alcohol Drinking -MH - Cardiotonic Agents -MH - Cardiovascular Diseases/*prevention & control -MH - Ethanol/*pharmacology -MH - Heart/drug effects -MH - Humans -MH - Risk Factors -EDAT- 2012/08/09 06:00 -MHDA- 2013/05/17 06:00 -CRDT- 2012/08/09 06:00 -PHST- 2012/08/09 06:00 [entrez] -PHST- 2012/08/09 06:00 [pubmed] -PHST- 2013/05/17 06:00 [medline] -AID - 10.1097/HCO.0b013e328356dc30 [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2012 Sep;27(5):550-5. doi: 10.1097/HCO.0b013e328356dc30. - -PMID- 21421082 -OWN - NLM -STAT- MEDLINE -DCOM- 20120118 -LR - 20250529 -IS - 1556-3871 (Electronic) -IS - 1547-5271 (Print) -IS - 1547-5271 (Linking) -VI - 8 -IP - 8 -DP - 2011 Aug -TI - Electrophysiologic basis for the antiarrhythmic actions of ranolazine. -PG - 1281-90 -LID - 10.1016/j.hrthm.2011.03.045 [doi] -AB - Ranolazine is a Food and Drug Administration-approved antianginal agent. - Experimental and clinical studies have shown that ranolazine has antiarrhythmic - effects in both ventricles and atria. In the ventricles, ranolazine can suppress - arrhythmias associated with acute coronary syndrome, long QT syndrome, heart - failure, ischemia, and reperfusion. In atria, ranolazine effectively suppresses - atrial tachyarrhythmias and atrial fibrillation (AF). Recent studies have shown - that the drug may be effective and safe in suppressing AF when used as a - pill-in-the pocket approach, even in patients with structurally compromised - hearts, warranting further study. The principal mechanism underlying ranolazine's - antiarrhythmic actions is thought to be primarily via inhibition of late I(Na) in - the ventricles and via use-dependent inhibition of peak I(Na) and I(Kr) in the - atria. Short- and long-term safety of ranolazine has been demonstrated in the - clinic, even in patients with structural heart disease. This review summarizes - the available data regarding the electrophysiologic actions and antiarrhythmic - properties of ranolazine in preclinical and clinical studies. -CI - Copyright © 2011 Heart Rhythm Society. Published by Elsevier Inc. All rights - reserved. -FAU - Antzelevitch, Charles -AU - Antzelevitch C -AD - Masonic Medical Research Laboratory, Utica, New York, USA. ca@mmrl.edu -FAU - Burashnikov, Alexander -AU - Burashnikov A -FAU - Sicouri, Serge -AU - Sicouri S -FAU - Belardinelli, Luiz -AU - Belardinelli L -LA - eng -GR - R01 HL047678/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Review -DEP - 20110321 -PL - United States -TA - Heart Rhythm -JT - Heart rhythm -JID - 101200317 -RN - 0 (Acetanilides) -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Calcium Channels) -RN - 0 (Ion Channels) -RN - 0 (Piperazines) -RN - 0 (Potassium Channels) -RN - A6IEZ5M406 (Ranolazine) -SB - IM -CIN - Heart Rhythm. 2011 Aug;8(8):1291-2. doi: 10.1016/j.hrthm.2011.06.007. PMID: - 21699867 -MH - Acetanilides/*pharmacology -MH - Action Potentials -MH - Animals -MH - Anti-Arrhythmia Agents/*pharmacology -MH - Arrhythmias, Cardiac/*drug therapy/physiopathology -MH - Calcium Channels/drug effects -MH - Electrophysiologic Techniques, Cardiac -MH - Heart/*physiopathology -MH - Heart Atria/drug effects/physiopathology -MH - Heart Ventricles/cytology/drug effects -MH - Humans -MH - Ion Channels/drug effects -MH - Membrane Potentials -MH - Myocytes, Cardiac/drug effects/physiology -MH - Piperazines/*pharmacology -MH - Potassium Channels/drug effects -MH - Ranolazine -MH - Species Specificity -PMC - PMC3131428 -MID - NIHMS282342 -COIS- Conflicts of Interest: Dr. Antzelevitch received a research grant and serves as a - consultant to Gilead Sciences and Dr. Belardinelli is employed by Gilead - Sciences. -EDAT- 2011/03/23 06:00 -MHDA- 2012/01/19 06:00 -PMCR- 2012/08/01 -CRDT- 2011/03/23 06:00 -PHST- 2011/02/23 00:00 [received] -PHST- 2011/03/11 00:00 [accepted] -PHST- 2011/03/23 06:00 [entrez] -PHST- 2011/03/23 06:00 [pubmed] -PHST- 2012/01/19 06:00 [medline] -PHST- 2012/08/01 00:00 [pmc-release] -AID - S1547-5271(11)00345-6 [pii] -AID - 10.1016/j.hrthm.2011.03.045 [doi] -PST - ppublish -SO - Heart Rhythm. 2011 Aug;8(8):1281-90. doi: 10.1016/j.hrthm.2011.03.045. Epub 2011 - Mar 21. - -PMID- 22041335 -OWN - NLM -STAT- MEDLINE -DCOM- 20120326 -LR - 20250626 -IS - 1532-8414 (Electronic) -IS - 1071-9164 (Linking) -VI - 17 -IP - 11 -DP - 2011 Nov -TI - Catheter ablation for atrial fibrillation in patients with left ventricular - systolic dysfunction. A systematic review and meta-analysis. -PG - 964-70 -LID - 10.1016/j.cardfail.2011.07.009 [doi] -AB - BACKGROUND: Atrial fibrillation (AF) and heart failure are often coexisting major - public health burdens. Although several studies have reported partial restoration - of systolic left ventricular (LV) function after catheter ablation for AF, the - method is not widely applied in patients with LV dysfunction. We reviewed the - results of AF ablation in patients with systolic LV dysfunction. METHODS AND - RESULTS: PubMed was searched for studies published after 2000 reporting original - data on AF catheter ablation in adult patients with systolic LV dysfunction. - Primary end point was the change of LV ejection fraction (LVEF) after catheter - ablation; secondary endpoints were the changes of exercise capacity and quality - of life after the procedure. We calculated mean difference (MD) of LVEF and 95% - confidence interval (95% CI) using random-effects models. Heterogeneity was - investigated by I(2) statistic, publication bias with Egger's test. The impact of - covariates on LVEF improvement was evaluated with meta-regression analyses. Nine - studies with a total of 354 patients with systolic LV dysfunction were analyzed. - Study patients were mainly male with mean age 49 to 62 years, LVEF was moderately - impaired and ranged in all but 1 study from 35% to 43%. LVEF improved after - ablation with a MD of 11.1% (95% CI: 7.1-15.2, P < .001). Heterogeneity among - analyzed studies was significant (I(2) = 92.9, P < .001). No potential - publication bias was found. In meta-regression analyses, the proportion of - patients with coronary artery disease was inversely related with LVEF improvement - (P < .0001) whereas there was no association between the LVEF change and the - proportion of patients with nonparoxysmal AF or the proportion of patients - without AF recurrences during follow-up. CONCLUSIONS: AF ablation in patients - with systolic LV dysfunction results in significant improvement of LV function, - but the extent of this improvement is heterogeneous. Patients with coronary - artery disease seem to benefit less than patients with other underlying diseases. - These results may be explained by patient selection. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Dagres, Nikolaos -AU - Dagres N -AD - University of Athens, Second Cardiology Department, Attikon University Hospital, - Athens, Greece. nikolaosdagres@yahoo.de -FAU - Varounis, Christos -AU - Varounis C -FAU - Gaspar, Thomas -AU - Gaspar T -FAU - Piorkowski, Christopher -AU - Piorkowski C -FAU - Eitel, Charlotte -AU - Eitel C -FAU - Iliodromitis, Efstathios K -AU - Iliodromitis EK -FAU - Lekakis, John P -AU - Lekakis JP -FAU - Flevari, Panayota -AU - Flevari P -FAU - Simeonidou, Eftihia -AU - Simeonidou E -FAU - Rallidis, Loukianos S -AU - Rallidis LS -FAU - Tsougos, Elias -AU - Tsougos E -FAU - Hindricks, Gerhard -AU - Hindricks G -FAU - Sommer, Philipp -AU - Sommer P -FAU - Anastasiou-Nana, Maria -AU - Anastasiou-Nana M -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -DEP - 20110909 -PL - United States -TA - J Card Fail -JT - Journal of cardiac failure -JID - 9442138 -SB - IM -MH - Atrial Fibrillation/pathology/*surgery -MH - Catheter Ablation/instrumentation/*methods -MH - Comorbidity -MH - Confidence Intervals -MH - Exercise Tolerance -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Risk Assessment -MH - Stroke Volume -MH - Systole -MH - Ventricular Dysfunction, Left/*pathology -MH - Ventricular Function, Left -EDAT- 2011/11/02 06:00 -MHDA- 2012/03/27 06:00 -CRDT- 2011/11/02 06:00 -PHST- 2011/04/14 00:00 [received] -PHST- 2011/07/16 00:00 [revised] -PHST- 2011/07/28 00:00 [accepted] -PHST- 2011/11/02 06:00 [entrez] -PHST- 2011/11/02 06:00 [pubmed] -PHST- 2012/03/27 06:00 [medline] -AID - S1071-9164(11)01044-X [pii] -AID - 10.1016/j.cardfail.2011.07.009 [doi] -PST - ppublish -SO - J Card Fail. 2011 Nov;17(11):964-70. doi: 10.1016/j.cardfail.2011.07.009. Epub - 2011 Sep 9. - -PMID- 23677721 -OWN - NLM -STAT- MEDLINE -DCOM- 20160418 -LR - 20140422 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 21 -IP - 2 -DP - 2014 -TI - Cardiac pathology and modern therapeutic approach in Behçet disease. -PG - 105-14 -LID - 10.5603/CJ.a2013.0056 [doi] -AB - Behçet disease (BD) is an enigmatic inflammatory disorder with multisystemic - complications which is endemic in some countries but can be seen in the entire - world. Valid diagnostic criteria are available. The pathology is related to a - specific perivasculitis with involvement of both arteries and veins of all sizes. - Minor arterial and cardiac involvement is frequent in BD but is usually - asymptomatic. In exceptional cases cardiac symptoms may be the 1st manifestation - of BD. The prevalence of severe cardiac complications (cardio-Behçet) should be < - 10%. An impressive therapeutic improvement has been achieved by using appropriate - catheterization techniques, coronary and intra-arterial stents, colchicine, - drug-response modifying drugs and immunotherapy but, still cardio-Behçet has a - poor prognosis. Efforts are undertaken to improve morbidity and prognosis with - the use of newer drugs. An important part of the complications in BD are related - to the frequent thromboembolic complications and there is high possibility that - newer oral anticoagulants will be superior to the classical anticoagulants - presently used. Available biologic agents have already been frequently used and - seem to have improved the prognosis, but efforts are undertaken to find newer - biologic agents with better therapeutic performance and less side-effects. - Summarizing as much as possible the effects of the presently used biotherapy in - BD, interferon-alpha is effective against many ocular, genital and perhaps - vascular manifestations, but its effectiveness is limited by frequent - adverse-effects (even if not dangerous for the cardiovascular system). Infliximab - is a valid option in the therapy of ocular and cutaneous manifestations but it is - less convincing in the therapy of vascular manifestations in vascular- and - neuro-Behçet; furthermore, side-effects, including severe cardiovascular - complications, are seen in a minority of patients; perhaps worse, infliximab - seems to loose efficacy in the long-term therapy, while pharmacogenetics and - receptor polymorphism may explain the existence of non-responders and the - occurrence of resistance. Adalimumab might be a promising alternative for - infliximab and seems to exert a good effect in an eurysmatic and other vascular - complications. However, we lack long-term studies. Other biologic agents have - been used only in few cases and it is too early to say if they offer new - therapeutic perspectives. -FAU - Cocco, Giuseppe -AU - Cocco G -AD - Cardiology Office, Rheinfelden, Switzerland. praxis@cocco.ch. -FAU - Jerie, Paul -AU - Jerie P -LA - eng -PT - Journal Article -PT - Review -DEP - 20130515 -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Anticoagulants) -RN - 0 (Biological Products) -SB - IM -MH - Administration, Oral -MH - Anti-Inflammatory Agents/adverse effects/*therapeutic use -MH - Anticoagulants/administration & dosage -MH - Behcet Syndrome/epidemiology/pathology/physiopathology/*therapy -MH - Biological Products/adverse effects/*therapeutic use -MH - Heart Diseases/epidemiology/pathology/physiopathology/*therapy -MH - Humans -MH - Myocardium/*pathology -MH - Predictive Value of Tests -MH - Prevalence -MH - Risk Factors -MH - Treatment Outcome -EDAT- 2013/05/17 06:00 -MHDA- 2016/04/19 06:00 -CRDT- 2013/05/17 06:00 -PHST- 2013/04/07 00:00 [received] -PHST- 2013/04/19 00:00 [accepted] -PHST- 2013/04/16 00:00 [revised] -PHST- 2013/05/17 06:00 [entrez] -PHST- 2013/05/17 06:00 [pubmed] -PHST- 2016/04/19 06:00 [medline] -AID - VM/OJS/J/33993 [pii] -AID - 10.5603/CJ.a2013.0056 [doi] -PST - ppublish -SO - Cardiol J. 2014;21(2):105-14. doi: 10.5603/CJ.a2013.0056. Epub 2013 May 15. - -PMID- 17198037 -OWN - NLM -STAT- MEDLINE -DCOM- 20070330 -LR - 20191110 -IS - 0887-9303 (Print) -IS - 0887-9303 (Linking) -VI - 30 -IP - 1 -DP - 2007 Jan-Mar -TI - Cardiac resynchronization therapy. -PG - 58-66 -AB - About 30% of patients with left ventricular systolic dysfunction also have - ventricular conduction delays (prolonged QRS duration greater than 0.12 second) - most frequently seen as left bundle branch block. This intraventricular - conduction delay causes nonsynchronous ventricular activation between the right - ventricle and the left ventricle (or dyssychrony), compromising cardiac function. - Cardiac resynchronization therapy, or biventricular pacing, is a recent - intervention for ventricular dyssychrony that incorporates 3 leads for pacing the - right atrium and simultaneous pacing of the right ventricle and left ventricle. - Left ventricular lead placement can be difficult to implant because of coronary - venous anatomy and can require longer procedure time for the patient. Restoring - ventricular synchrony has been shown to decrease septal wall dyskinesis, decrease - mitral regurgitation, increase left ventricular filling time, decrease pulmonary - capillary wedge pressure, and reverse ventricular modeling. -FAU - Saul, Lauren -AU - Saul L -AD - University of Pittsburgh Medical Center, Presbyterian Shadyside-Shadyside Campus, - Pittsburgh, PA 15232, USA. saullm@upmc.edu -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Nurs Q -JT - Critical care nursing quarterly -JID - 8704517 -MH - Aged, 80 and over -MH - Bundle-Branch Block/complications/diagnosis/*therapy -MH - Chronic Disease -MH - Contraindications -MH - Critical Care/*methods -MH - Electrocardiography -MH - Heart Failure/etiology/*prevention & control -MH - Humans -MH - Male -MH - *Pacemaker, Artificial/adverse effects -MH - Patient Education as Topic -MH - Patient Selection -MH - Perioperative Care/methods/nursing -MH - Treatment Outcome -MH - Ventricular Dysfunction, Left/complications/diagnosis/*therapy -RF - 33 -EDAT- 2007/01/02 09:00 -MHDA- 2007/03/31 09:00 -CRDT- 2007/01/02 09:00 -PHST- 2007/01/02 09:00 [pubmed] -PHST- 2007/03/31 09:00 [medline] -PHST- 2007/01/02 09:00 [entrez] -AID - 00002727-200701000-00007 [pii] -AID - 10.1097/00002727-200701000-00007 [doi] -PST - ppublish -SO - Crit Care Nurs Q. 2007 Jan-Mar;30(1):58-66. doi: - 10.1097/00002727-200701000-00007. - -PMID- 16699351 -OWN - NLM -STAT- MEDLINE -DCOM- 20060925 -LR - 20191109 -IS - 1550-5049 (Electronic) -IS - 0889-4655 (Linking) -VI - 21 -IP - 3 -DP - 2006 May-Jun -TI - Considerations in prevention of surgical site infections following cardiac - surgery: when your patient is diabetic. -PG - E14-20 -AB - The incidence of surgical site infections among patients with diabetes continues - to occur at a greater rate when compared with their nondiabetic counterparts. - Preexisting vascular changes, delayed wound healing, and impaired immune factors - contribute. Adult patients with diabetes likely possess comorbid coronary artery - disease, thus increasing the need for cardiac surgery. The resultant potential - for infection can be combated with supplementary interventions above those - universally taken. Modifiable risk factors of hyperglycemia and obesity are - targeted preoperatively. Glycemic control, adequate tissue perfusion, and adjunct - use of nasal mupirocin are addressed intraoperatively. Lastly, focus is placed on - nutrition, exercise, and continued glucose control postoperatively and beyond - discharge. -FAU - Streeter, Norman Blaine -AU - Streeter NB -AD - James A. Haley Veteran's Hospital-Cardiology, Tampa, FL 33612, USA. - norman.streeter@med.va.gov -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Cardiovasc Nurs -JT - The Journal of cardiovascular nursing -JID - 8703516 -RN - 0 (Blood Glucose) -RN - 0 (Hypoglycemic Agents) -RN - 0 (Insulin) -SB - IM -MH - Bandages -MH - Blood Glucose/metabolism -MH - Diabetes Complications/blood/*nursing/physiopathology/*prevention & control -MH - Heart Diseases/nursing/*surgery -MH - Humans -MH - Hypoglycemic Agents/therapeutic use -MH - Insulin/therapeutic use -MH - Nose/microbiology -MH - Nutritional Physiological Phenomena -MH - Patient Education as Topic/methods -MH - Perioperative Nursing/*methods -MH - Postoperative Care/methods/nursing -MH - Preoperative Care/methods -MH - Risk Factors -MH - Staphylococcal Infections/prevention & control -MH - Staphylococcus aureus/drug effects/isolation & purification -MH - Surgical Wound Infection/*nursing/physiopathology/*prevention & control -MH - Wound Healing -RF - 47 -EDAT- 2006/05/16 09:00 -MHDA- 2006/09/26 09:00 -CRDT- 2006/05/16 09:00 -PHST- 2006/05/16 09:00 [pubmed] -PHST- 2006/09/26 09:00 [medline] -PHST- 2006/05/16 09:00 [entrez] -AID - 00005082-200605000-00014 [pii] -AID - 10.1097/00005082-200605000-00014 [doi] -PST - ppublish -SO - J Cardiovasc Nurs. 2006 May-Jun;21(3):E14-20. doi: - 10.1097/00005082-200605000-00014. - -PMID- 17498573 -OWN - NLM -STAT- MEDLINE -DCOM- 20070731 -LR - 20220410 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 49 -IP - 19 -DP - 2007 May 15 -TI - Tissue Doppler imaging a new prognosticator for cardiovascular diseases. -PG - 1903-14 -AB - Tissue Doppler imaging (TDI) is evolving as a useful echocardiographic tool for - quantitative assessment of left ventricular (LV) systolic and diastolic function. - Recent studies have explored the prognostic role of TDI-derived parameters in - major cardiac diseases, such as heart failure, acute myocardial infarction, and - hypertension. In these conditions, myocardial mitral annular or basal segmental - (Sm) systolic and early diastolic (Ea or Em) velocities have been shown to - predict mortality or cardiovascular events. In particular, those with reduced Sm - or Em values of <3 cm/s have a very poor prognosis. In heart failure and after - myocardial infarction, noninvasive assessment of LV diastolic pressure by - transmitral to mitral annular early diastolic velocity ratio (E/Ea or E/Em) is a - strong prognosticator, especially when E/Ea is > or =15. In addition, systolic - intraventricular dyssynchrony measured by segmental analysis of myocardial - velocities is another independent predictor of adverse clinical outcome in heart - failure subjects, even when the QRS duration is normal. In heart failure patients - who received cardiac resynchronization therapy, the presence of systolic - dyssynchrony at baseline is associated with favorable LV remodeling, which in - turn predicts a favorable long-term clinical outcome. Finally, TDI and derived - deformation parameters improve prognostic assessment during dobutamine stress - echocardiography. A high mean Sm value in the basal segments of patients with - suspected coronary artery disease is associated with lower mortality rate or - myocardial infarction and is superior to the wall motion score. -FAU - Yu, Cheuk-Man -AU - Yu CM -AD - Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales - Hospital, Chinese University of Hong Kong, Hong Kong, China. cmyu@cuhk.edu.hk -FAU - Sanderson, John E -AU - Sanderson JE -FAU - Marwick, Thomas H -AU - Marwick TH -FAU - Oh, Jae K -AU - Oh JK -LA - eng -PT - Journal Article -PT - Review -DEP - 20070430 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -CIN - J Am Coll Cardiol. 2007 Oct 16;50(16):1614; author reply 1615. doi: - 10.1016/j.jacc.2007.06.044. PMID: 17936165 -MH - Cardiovascular Diseases/*diagnostic imaging/physiopathology/therapy -MH - *Echocardiography, Doppler -MH - Humans -MH - Myocardial Contraction/physiology -MH - Prognosis -MH - Stroke Volume/physiology -RF - 67 -EDAT- 2007/05/15 09:00 -MHDA- 2007/08/01 09:00 -CRDT- 2007/05/15 09:00 -PHST- 2006/03/07 00:00 [received] -PHST- 2007/01/19 00:00 [revised] -PHST- 2007/01/22 00:00 [accepted] -PHST- 2007/05/15 09:00 [pubmed] -PHST- 2007/08/01 09:00 [medline] -PHST- 2007/05/15 09:00 [entrez] -AID - S0735-1097(07)00759-0 [pii] -AID - 10.1016/j.jacc.2007.01.078 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2007 May 15;49(19):1903-14. doi: 10.1016/j.jacc.2007.01.078. - Epub 2007 Apr 30. - -PMID- 17017685 -OWN - NLM -STAT- MEDLINE -DCOM- 20070111 -LR - 20190922 -IS - 0001-5458 (Print) -IS - 0001-5458 (Linking) -VI - 106 -IP - 4 -DP - 2006 Jul-Aug -TI - Perioperative cardiac risk stratification and modification in abdominal aortic - aneurysm repair. -PG - 361-6 -AB - Cardiovascular complications are important causes of morbidity and mortality - following vascular surgery. Adequate preoperative risk assessment and - perioperative management may modify postoperative mortality and morbidity and - improve long-term prognosis. The objective of this review is to examine the - present day knowledge regarding the preoperative evaluation and perioperative - management of patients undergoing noncardiac surgery, focusing specifically on - abdominal aortic aneurysm (AAA) repair. Clinical markers combined with ECG and - surgical risk assessment can effectively divide patients in a truly low-risk, - intermediate and high-risk population. Low-risk patients can probably be operated - on without additional cardiac testing. Notably, due to the surgical risk, AAA - patients are never low-risk patients. Intermediate-risk and high-risk patients - are referred for cardiac testing to exclude extensive stress induced myocardial - ischemia, as beta-blockers provide insufficient myocardial protection in this - case and preoperative coronary revascularization might be considered. Whether - patients at intermediate risk without ischemic heart disease should be treated - with statins and/or beta-blockers is still controversial. In high-risk patients, - it is strongly advised to administer beta-blockers with heart rate determined - dose adjustment, while the effects of preoperative revascularization remain - subject to debate. -FAU - Dunkelgrun, M -AU - Dunkelgrun M -AD - Vascular Surgery, Erasmus Medical Center, Rotterdam, The Netherlands. -FAU - Schouten, O -AU - Schouten O -FAU - Feringa, H H H -AU - Feringa HH -FAU - Noordzij, P G -AU - Noordzij PG -FAU - Hoeks, S -AU - Hoeks S -FAU - Boersma, E -AU - Boersma E -FAU - Bax, J J -AU - Bax JJ -FAU - Poldermans, D -AU - Poldermans D -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Acta Chir Belg -JT - Acta chirurgica Belgica -JID - 0370571 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Biomarkers) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Aortic Aneurysm, Abdominal/*surgery -MH - Biomarkers/analysis -MH - Electrocardiography -MH - Heart Diseases/*prevention & control -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - *Perioperative Care -MH - Postoperative Complications/*prevention & control -MH - Risk Assessment -MH - Risk Factors -RF - 33 -EDAT- 2006/10/05 09:00 -MHDA- 2007/01/12 09:00 -CRDT- 2006/10/05 09:00 -PHST- 2006/10/05 09:00 [pubmed] -PHST- 2007/01/12 09:00 [medline] -PHST- 2006/10/05 09:00 [entrez] -AID - 10.1080/00015458.2006.11679908 [doi] -PST - ppublish -SO - Acta Chir Belg. 2006 Jul-Aug;106(4):361-6. doi: 10.1080/00015458.2006.11679908. - -PMID- 21555886 -OWN - NLM -STAT- MEDLINE -DCOM- 20111215 -LR - 20161125 -IS - 1421-9751 (Electronic) -IS - 0008-6312 (Linking) -VI - 118 -IP - 2 -DP - 2011 -TI - Prediction of life-threatening arrhythmias--still an unresolved problem. -PG - 129-37 -LID - 10.1159/000327093 [doi] -AB - A major challenge in current cardiology is to predict who will die suddenly from - ventricular arrhythmias. Ventricular arrhythmias are the most common cause of - sudden cardiac death, occurring in about 1-2:1,000 inhabitants yearly, and is - most frequently due to coronary artery disease. Patients with increased risk of - ventricular arrhythmias can be offered medical treatment and ultimately an - implantable cardioverter defibrillator (ICD). Left ventricular ejection fraction - (EF) is currently the main risk stratification tool used to select patients for - ICD therapy. However, EF is insufficient in predicting arrhythmic risk. A number - of techniques have been presented to improve arrhythmic risk stratification - without having reached clinical utility. Conduction abnormalities and dispersion - of action potential duration forms the substrate for malignant ventricular - arrhythmias in infarcted tissue as in several cardiomyopathies. The ability to - assess electrical dispersion in patients noninvasively has been limited. - Myocardial strain by echocardiography has been presented as an accurate tool for - assessing myocardial function and timing. Inhomogeneous and dispersed myocardial - contraction has been related to the occurrence of ventricular arrhythmias and - seems to be a promising tool in risk stratification. This review focuses on - arrhythmia mechanisms and novel echocardiographic tools for assessing risk of - ventricular arrhythmias. -CI - Copyright © 2011 S. Karger AG, Basel. -FAU - Haugaa, Kristina Hermann -AU - Haugaa KH -AD - Department of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway. -FAU - Edvardsen, Thor -AU - Edvardsen T -FAU - Amlie, Jan P -AU - Amlie JP -LA - eng -PT - Journal Article -PT - Review -DEP - 20110510 -PL - Switzerland -TA - Cardiology -JT - Cardiology -JID - 1266406 -RN - 0 (Adrenergic beta-Antagonists) -SB - IM -CIN - Cardiology. 2011;120(1):50-1. doi: 10.1159/000333009. PMID: 22116410 -MH - Adrenergic beta-Antagonists/therapeutic use -MH - *Arrhythmias, Cardiac/diagnostic imaging/physiopathology/therapy -MH - Death, Sudden, Cardiac -MH - Defibrillators, Implantable -MH - Echocardiography -MH - *Heart Ventricles/diagnostic imaging/physiopathology -MH - Humans -MH - Long QT Syndrome/drug therapy/genetics -MH - Risk Factors -EDAT- 2011/05/11 06:00 -MHDA- 2011/12/16 06:00 -CRDT- 2011/05/11 06:00 -PHST- 2011/01/18 00:00 [received] -PHST- 2011/03/01 00:00 [accepted] -PHST- 2011/05/11 06:00 [entrez] -PHST- 2011/05/11 06:00 [pubmed] -PHST- 2011/12/16 06:00 [medline] -AID - 000327093 [pii] -AID - 10.1159/000327093 [doi] -PST - ppublish -SO - Cardiology. 2011;118(2):129-37. doi: 10.1159/000327093. Epub 2011 May 10. - -PMID- 20381381 -OWN - NLM -STAT- MEDLINE -DCOM- 20110225 -LR - 20101115 -IS - 1879-1336 (Electronic) -IS - 1054-8807 (Linking) -VI - 19 -IP - 6 -DP - 2010 Nov-Dec -TI - Sudden cardiac death with normal heart: molecular autopsy. -PG - 321-5 -LID - 10.1016/j.carpath.2010.02.003 [doi] -AB - Several culprits may be identified at postmortem in sudden death (SD) victims, - including coronary artery, myocardial, valve, conduction system, and congenital - heart diseases. However, particularly in young people, the heart can be found - grossly and histologically normal in a not-so-minor amount of cases (the - so-called unexplained SD or "mors sine materia") and inherited ion channel - diseases are implicated (long and short QT syndromes, Brugada syndrome, and - catecholaminergic polymorphic ventricular tachycardia). These channelopathies are - due to defective genes encoding for proteins of sodium and potassium ion channels - at the sarcolemma level or for receptors regulating intracellular calcium release - at the sarcoplasmic reticulum level. Postmortem investigation may still represent - the first opportunity to make the proper diagnosis also in the setting of a - structurally normal heart and the employment of molecular biology techniques is - of help to solve the puzzle of such "silent" autopsies. For these reasons, - autopsy investigation of cardiac SD should always include sampling for genetic - testing to search for the invisible inherited arrhythmogenic disorders, as - recommended in the recent guidelines by the Association for European - Cardiovascular Pathology. -CI - Copyright © 2010 Elsevier Inc. All rights reserved. -FAU - Basso, Cristina -AU - Basso C -AD - Department of Medical Diagnostic Sciences and Special Therapies, University of - Padua Medical School, Padua, Italy. cristina.basso@unipd.it -FAU - Carturan, Elisa -AU - Carturan E -FAU - Pilichou, Kalliopi -AU - Pilichou K -FAU - Rizzo, Stefania -AU - Rizzo S -FAU - Corrado, Domenico -AU - Corrado D -FAU - Thiene, Gaetano -AU - Thiene G -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100409 -PL - United States -TA - Cardiovasc Pathol -JT - Cardiovascular pathology : the official journal of the Society for Cardiovascular - Pathology -JID - 9212060 -RN - 0 (Ion Channels) -SB - IM -MH - Adolescent -MH - Adult -MH - Age Factors -MH - Arrhythmias, Cardiac/complications/*genetics/mortality/pathology -MH - Autopsy -MH - Cause of Death -MH - Child -MH - Child, Preschool -MH - Death, Sudden, Cardiac/*etiology/pathology -MH - Genetic Predisposition to Disease -MH - *Genetic Testing -MH - Humans -MH - Infant -MH - Ion Channels/*genetics -MH - *Mutation -MH - Myocardium/pathology -MH - Risk Factors -MH - Young Adult -EDAT- 2010/04/13 06:00 -MHDA- 2011/02/26 06:00 -CRDT- 2010/04/13 06:00 -PHST- 2010/01/08 00:00 [received] -PHST- 2010/02/22 00:00 [accepted] -PHST- 2010/04/13 06:00 [entrez] -PHST- 2010/04/13 06:00 [pubmed] -PHST- 2011/02/26 06:00 [medline] -AID - S1054-8807(10)00032-3 [pii] -AID - 10.1016/j.carpath.2010.02.003 [doi] -PST - ppublish -SO - Cardiovasc Pathol. 2010 Nov-Dec;19(6):321-5. doi: 10.1016/j.carpath.2010.02.003. - Epub 2010 Apr 9. - -PMID- 19761100 -OWN - NLM -STAT- MEDLINE -DCOM- 20091117 -LR - 20181201 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 10 -IP - 7 -DP - 2009 Jul -TI - [Inotrope therapy in acute heart failure: a critical review of clinical and - scientific evidence for levosimendan in the context of traditional treatment]. -PG - 422-33 -AB - The clinical heterogeneity of acute heart failure and the low number of - controlled trials, to date, are the main causes of the lack of agreement on - therapeutic objectives, uncertainty on the most appropriate management, and - difficulties to obtain robust evidence for the treatment of this syndrome. The - inappropriate use of inotropic agents is one the most common pitfalls shown by - registries. Two to 10% of patients admitted for acute heart failure present with - a low output syndrome, a clinical profile associated with high mortality, where - inotropes may be a rational therapeutic choice. Crucial points for an effective - use of inotropes are an accurate evaluation and selection of patients, tailoring - of therapeutic schemes and strict patient monitoring. Beta-adrenergic agonists - and phosphodiesterase inhibitors increase myocardial oxygen demand, favor - arrhythmias and may cause peripheral vasodilation with a secondary decrease in - coronary perfusion pressure. These effects may translate in myocardial ischemia, - loss of cardiomyocytes and accelerated ventricular remodeling with worse - prognosis. Levosimendan, a novel inotropic agent studied according to the - principles of evidence-based medicine, augments myocardial contractility without - changes in intracellular calcium concentrations, and with minimal impact on - myocardial oxygen consumption. This paper, based on an expert consensus, aims to - suggest criteria for the appropriate use of inotropic agents in acute heart - failure, based on a critical appraisal of the existing evidence and clinical - experience. -FAU - Ambrosio, Giuseppe -AU - Ambrosio G -AD - Cardiologia e Fisiopatologia Cardiovascolare, Università e Azienda Ospedaliera di - Perugia, Trieste. -FAU - Di Lenarda, Andrea -AU - Di Lenarda A -FAU - Fedele, Francesco -AU - Fedele F -FAU - Gabrielli, Domenico -AU - Gabrielli D -FAU - Metra, Marco -AU - Metra M -FAU - Oliva, Fabrizio -AU - Oliva F -FAU - Perna, Gianpiero -AU - Perna G -FAU - Senni, Michele -AU - Senni M -FAU - De Maria, Renata -AU - De Maria R -LA - ita -PT - Journal Article -PT - Review -TT - Terapia con inotropi nello scompenso cardiaco acuto: rivisitazione critica delle - evidenze scientifiche e cliniche per levosimendan nel contesto del trattamento - tradizionale. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -RN - 0 (Cardiotonic Agents) -RN - 0 (Hydrazones) -RN - 0 (Pyridazines) -RN - 349552KRHK (Simendan) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Acute Disease -MH - Algorithms -MH - Calcium/*metabolism -MH - Cardiotonic Agents/pharmacology/*therapeutic use -MH - Clinical Trials as Topic -MH - *Evidence-Based Medicine -MH - Heart Failure/diagnosis/*drug therapy/metabolism/mortality -MH - Humans -MH - Hydrazones/pharmacology/*therapeutic use -MH - Myocardial Contraction/*drug effects -MH - Patient Selection -MH - Prognosis -MH - Pyridazines/pharmacology/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Severity of Illness Index -MH - Simendan -MH - Treatment Outcome -RF - 71 -EDAT- 2009/09/19 06:00 -MHDA- 2009/11/18 06:00 -CRDT- 2009/09/19 06:00 -PHST- 2009/09/19 06:00 [entrez] -PHST- 2009/09/19 06:00 [pubmed] -PHST- 2009/11/18 06:00 [medline] -PST - ppublish -SO - G Ital Cardiol (Rome). 2009 Jul;10(7):422-33. - -PMID- 18462260 -OWN - NLM -STAT- MEDLINE -DCOM- 20090723 -LR - 20081017 -IS - 1365-2265 (Electronic) -IS - 0300-0664 (Linking) -VI - 69 -IP - 3 -DP - 2008 Sep -TI - The GH-IGF-I axis and the cardiovascular system: clinical implications. -PG - 347-58 -LID - 10.1111/j.1365-2265.2008.03292.x [doi] -AB - BACKGROUND: GH and IGF-I affect cardiac structure and performance. In the general - population, low IGF-I has been associated with higher prevalence of ischaemic - heart disease and mortality. Both in GH deficiency (GHD) and excess life - expectancy has been reported to be reduced because of cardiovascular disease. - OBJECTIVE: To review the role of the GH-IGF-I system on the cardiovascular - system. RESULTS: Recent epidemiological evidence suggests that serum IGF-I levels - in the low-normal range are associated with increased risk of acute myocardial - infarction, ischaemic heart disease, coronary and carotid artery atherosclerosis - and stroke. This confirms previous findings in patients with acromegaly or with - GH-deficiency showing cardiovascular impairment. Patients with either childhood- - or adulthood-onset GHD have cardiovascular abnormalities such as reduced cardiac - mass, diastolic filling and left ventricular response at peak exercise, increased - intima-media thickness and endothelial dysfunction. These abnormalities can be - reversed, at least partially, after GH replacement therapy. In contrast, in - acromegaly chronic GH and IGF-I excess causes a specific cardiomyopathy: - concentric cardiac hypertrophy (in more than two-thirds of the patients at - diagnosis) associated to diastolic dysfunction is the most common finding. In - later stages, impaired systolic function ending in heart failure can occur, if - GH/IGF-I excess is not controlled. Abnormalities of cardiac rhythm and of cardiac - valves can also occur. Successful control of acromegaly is accompanied by - decrease of the left ventricular mass and improvement of cardiac function. - CONCLUSION: The cardiovascular system is a target organ for GH and IGF-I. Subtle - dysfunction in the GH-IGF-I axis are correlated with increased prevalence of - ischaemic heart disease. Acromegaly and GHD are associated with several - abnormalities of the cardiovascular system and control of GH/IGF-I secretion - reverses (or at least stops) cardiovascular abnormalities. -FAU - Colao, Annamaria -AU - Colao A -AD - Department of Molecular and Clinical Endocrinology and Oncology, University of - Naples Federico II, Naples, Italy. colao@unina.it -LA - eng -PT - Journal Article -PT - Review -DEP - 20080506 -PL - England -TA - Clin Endocrinol (Oxf) -JT - Clinical endocrinology -JID - 0346653 -RN - 12629-01-5 (Human Growth Hormone) -RN - 67763-96-6 (Insulin-Like Growth Factor I) -SB - IM -MH - Acromegaly/metabolism/physiopathology -MH - Cardiovascular Diseases/etiology/metabolism -MH - *Cardiovascular Physiological Phenomena -MH - Cardiovascular System/metabolism/physiopathology -MH - Growth Disorders/metabolism/physiopathology -MH - Human Growth Hormone/deficiency/metabolism/*physiology -MH - Humans -MH - Insulin-Like Growth Factor I/metabolism/*physiology -MH - Models, Biological -MH - Signal Transduction/physiology -RF - 126 -EDAT- 2008/05/09 09:00 -MHDA- 2009/07/25 09:00 -CRDT- 2008/05/09 09:00 -PHST- 2008/05/09 09:00 [pubmed] -PHST- 2009/07/25 09:00 [medline] -PHST- 2008/05/09 09:00 [entrez] -AID - CEN3292 [pii] -AID - 10.1111/j.1365-2265.2008.03292.x [doi] -PST - ppublish -SO - Clin Endocrinol (Oxf). 2008 Sep;69(3):347-58. doi: - 10.1111/j.1365-2265.2008.03292.x. Epub 2008 May 6. - -PMID- 23358369 -OWN - NLM -STAT- MEDLINE -DCOM- 20140626 -LR - 20161125 -IS - 1536-0237 (Electronic) -IS - 0883-5993 (Linking) -VI - 28 -IP - 6 -DP - 2013 Nov -TI - Biostatistics in clinical decision making for cardiothoracic radiologists. -PG - 368-75 -LID - 10.1097/RTI.0b013e318281db88 [doi] -AB - Cardiothoracic radiologists are intuitively aware of sensitivity and specificity - as they pertain to diagnostic tests involving clinical information. However, many - cardiothoracic radiologists are unfamiliar with odds ratios, likelihood ratios, - predictive values, and receiver operating characteristic (ROC) curves, which - provide more information about the performance of a test. Our article will first - review the fundamental concepts of sensitivity, specificity, predictive values, - and likelihood ratios. The ROC curve methodology will be covered with an emphasis - on creating a look-up table, a straightforward table that communicates important - information to the clinician to aid in diagnosis. The article reviews sensitivity - and specificity, as well as predictive values, logistic regression, and ROC - curves, using conceptual principles without unnecessary mathematical rigor. We - will apply principles of sensitivity and specificity to continuous measurements - by constructing ROC curves in order to tie together key ideas in diagnostic - decision making. Three clinical examples are presented to illustrate these - fundamental statistical concepts: predictors of pulmonary embolism in children, - use of dobutamine-cardiac magnetic resonance imaging to identify impaired - ventricular function in patients who have suffered a myocardial infarction, and - diagnostic accuracy of 64-multidetector row computed tomography to identify - occluded vessels in adult patients with suspected coronary artery disease. In - addition, a glossary is provided at the end of the article with key terms - important in diagnostic imaging. An understanding of the concepts presented will - assist cardiothoracic radiologists in critically discerning the usefulness of - diagnostic tests and how these statistics can be applied to make judgments and - decisions that are essential to clinical practice. -FAU - Zurakowski, David -AU - Zurakowski D -AD - Departments of *Anesthesia †Radiology ‡Medicine, Pulmonary Division, Boston - Children's Hospital, Harvard Medical School, Boston, MA. -FAU - Johnson, Victor M -AU - Johnson VM -FAU - Lee, Edward Y -AU - Lee EY -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Thorac Imaging -JT - Journal of thoracic imaging -JID - 8606160 -SB - IM -MH - Child -MH - *Decision Making -MH - Heart Diseases/*diagnostic imaging/physiopathology -MH - Humans -MH - Immobilization -MH - Likelihood Functions -MH - Logistic Models -MH - Lung Diseases/*diagnostic imaging/physiopathology -MH - Magnetic Resonance Imaging -MH - Multidetector Computed Tomography -MH - Odds Ratio -MH - Pulmonary Embolism/diagnosis -MH - ROC Curve -MH - Sensitivity and Specificity -MH - Ventricular Function, Left -EDAT- 2013/01/30 06:00 -MHDA- 2014/06/27 06:00 -CRDT- 2013/01/30 06:00 -PHST- 2013/01/30 06:00 [entrez] -PHST- 2013/01/30 06:00 [pubmed] -PHST- 2014/06/27 06:00 [medline] -AID - 10.1097/RTI.0b013e318281db88 [doi] -PST - ppublish -SO - J Thorac Imaging. 2013 Nov;28(6):368-75. doi: 10.1097/RTI.0b013e318281db88. - -PMID- 20399520 -OWN - NLM -STAT- MEDLINE -DCOM- 20110322 -LR - 20241217 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 144 -IP - 1 -DP - 2010 Sep 24 -TI - Cardiac side-effects of cancer chemotherapy. -PG - 3-15 -LID - 10.1016/j.ijcard.2010.03.003 [doi] -AB - The spectrum of cardiac side-effects of cancer chemotherapy has expanded with the - development of combination, adjuvant and targeted chemotherapies. Their - administration in multiple regimens has increased greatly, including in older - patients and in patients with cardiovascular and/or coronary artery disease - (CAD). Cardiac toxicity of anthracyclines involves oxidative stress and - apoptosis. Early detection combines 2D-echocardiography and/or radionuclide - angiography and recent methods such as tissue Doppler imaging, strain rate - echocardiography and sampling of serial troponin and/or NT-proBNP levels. - Dexrazoxane has proven effective in the prevention of dose-related toxicity in - children and adults. High doses of the alkylating drugs cyclophosphamide and - ifosfamide may result in a reversible heart failure and in life-threatening - arrhythmias. Myocardial ischemia induced by the antimetabolites 5-fluorouracil - and capecitabine impacts prognosis of patients with prior CAD. Severe arrhythmias - may complicate administration of microtubule inhibitors. Targeted therapies with - the antibody-based tyrosine kinases (TK) inhibitors trastuzumab and, to a lesser - extent, alemtuzumab induce heart failure or asymptomatic LV dysfunction in 1-4% - and 10%, respectively. Cetuximab and rituximab induce hypotension, whereas - bevacizumab may promote severe hypertension and venous thromboembolism. Small - molecule TK inhibitors may also elicit LV dysfunction, in only few patients - treated with imatinib mesylate, but in a substantially higher proportion of those - receiving the multitargeted TK inhibitor sunitinib or the recently approved drugs - erlotinib, lapatinib and dasatinib. Management of patients at increased - cardiovascular risk associated with advancing age, previous CAD or targeted - therapies may be optimized by referral to a cardiologist in a cross-specialty - teamwork. -CI - Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. -FAU - Monsuez, Jean-Jacques -AU - Monsuez JJ -AD - AP-HP, Hôpital René Muret, Cardiologie, Policlinique médicale, Université - Paris-13, Faculté de Médecine de Bobigny, 93270 Sevran, France. - jean-jacques.monsuez@rmb.aphp.fr -FAU - Charniot, Jean-Christophe -AU - Charniot JC -FAU - Vignat, Noëlle -AU - Vignat N -FAU - Artigou, Jean-Yves -AU - Artigou JY -LA - eng -PT - Journal Article -PT - Review -DEP - 20100418 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Antineoplastic Agents) -SB - IM -MH - Antineoplastic Agents/*adverse effects -MH - Heart Diseases/*chemically induced -MH - Humans -MH - Neoplasms/*drug therapy -MH - Risk Factors -EDAT- 2010/04/20 06:00 -MHDA- 2011/03/23 06:00 -CRDT- 2010/04/20 06:00 -PHST- 2009/09/23 00:00 [received] -PHST- 2010/02/27 00:00 [revised] -PHST- 2010/03/06 00:00 [accepted] -PHST- 2010/04/20 06:00 [entrez] -PHST- 2010/04/20 06:00 [pubmed] -PHST- 2011/03/23 06:00 [medline] -AID - S0167-5273(10)00178-6 [pii] -AID - 10.1016/j.ijcard.2010.03.003 [doi] -PST - ppublish -SO - Int J Cardiol. 2010 Sep 24;144(1):3-15. doi: 10.1016/j.ijcard.2010.03.003. Epub - 2010 Apr 18. - -PMID- 24392265 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20220317 -IS - 2155-7772 (Print) -IS - 2155-7780 (Electronic) -IS - 2155-7780 (Linking) -VI - 15 -IP - 4 -DP - 2013 -TI - Diagnosis and treatment of depression in patients with congestive heart failure: - a review of the literature. -LID - 10.4088/PCC.13r01511 [doi] -LID - PCC.13r01511 -AB - CONTEXT: Major depressive disorder (MDD) can be challenging to diagnose in - patients with congestive heart failure, who often suffer from fatigue, insomnia, - weight changes, and other neurovegetative symptoms that overlap with those of - depression. Pathophysiologic mechanisms (eg, inflammation, autonomic nervous - system dysfunction, cardiac arrhythmias, and altered platelet function) connect - depression and congestive heart failure. OBJECTIVE: We sought to review the - prevalence, diagnosis, neurobiology, and treatment of depression associated with - congestive heart failure. DATA SOURCES: A search of all English-language articles - between January 2003 and January 2013 was conducted using the search terms - congestive heart failure and depression. STUDY SELECTION: We found 1,498 article - abstracts and 19 articles (meta-analyses, systematic reviews, and original - research articles) that were selected for inclusion, as they contained - information about our focus on diagnosis, treatment, and pathophysiology of - depression associated with congestive heart failure. The search was augmented - with manual review of reference lists of articles from the initial search. - Articles selected for review were determined by author consensus. DATA - EXTRACTION: The prevalence, diagnosis, neurobiology, and treatment of depression - associated with congestive heart failure were reviewed. Particular attention was - paid to the safety, efficacy, and tolerability of antidepressant medications - commonly used to treat depression and how their side-effect profiles impact the - pathophysiology of congestive heart failure. Drug-drug interactions between - antidepressant medications and medications used to treat congestive heart failure - were examined. RESULTS: MDD is highly prevalent in patients with congestive heart - failure. Moreover, the prevalence and severity of depression correlate with the - degree of cardiac dysfunction and development of congestive heart failure. - Depression increases the risk of congestive heart failure, particularly in those - patients with coronary artery disease , and is associated with a poorer quality - of life, increased use of health care resources, more frequent adverse clinical - events and hospitalizations, and twice the risk of mortality. CONCLUSIONS: At - present, limited empirical data exist with regard to treatment of depression in - the increasingly large population of patients with congestive heart failure. - Evidence reveals that both psychotherapeutic treatment (eg, cognitive-behavioral - therapy) and pharmacologic treatment (eg, use of the selective serotonin reuptake - inhibitor sertraline) are safe and effective in reducing depression severity in - patients with cardiovascular disease. Collaborative care programs featuring - interventions that work to improve adherence to medical and psychiatric - treatments improve both cardiovascular disease and depression outcomes. - Depression rating scales such as the 9-item Patient Health Questionnaire should - be used to monitor therapeutic efficacy. -FAU - Rustad, James K -AU - Rustad JK -AD - Department of Psychiatry and Behavioral Medicine, Morsani College of Medicine, - University of South Florida, Tampa, and Department of Psychiatry, University of - Central Florida College of Medicine, Orlando (Dr Rustad); Department of - Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston (Dr - Stern); Departments of Medicine (Ms Hebert) and Psychiatry (Dr Musselman), - University of Miami/Miller School of Medicine, Miami, Florida. -FAU - Stern, Theodore A -AU - Stern TA -AD - Department of Psychiatry and Behavioral Medicine, Morsani College of Medicine, - University of South Florida, Tampa, and Department of Psychiatry, University of - Central Florida College of Medicine, Orlando (Dr Rustad); Department of - Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston (Dr - Stern); Departments of Medicine (Ms Hebert) and Psychiatry (Dr Musselman), - University of Miami/Miller School of Medicine, Miami, Florida. -FAU - Hebert, Kathy A -AU - Hebert KA -AD - Department of Psychiatry and Behavioral Medicine, Morsani College of Medicine, - University of South Florida, Tampa, and Department of Psychiatry, University of - Central Florida College of Medicine, Orlando (Dr Rustad); Department of - Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston (Dr - Stern); Departments of Medicine (Ms Hebert) and Psychiatry (Dr Musselman), - University of Miami/Miller School of Medicine, Miami, Florida. -FAU - Musselman, Dominique L -AU - Musselman DL -AD - Department of Psychiatry and Behavioral Medicine, Morsani College of Medicine, - University of South Florida, Tampa, and Department of Psychiatry, University of - Central Florida College of Medicine, Orlando (Dr Rustad); Department of - Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston (Dr - Stern); Departments of Medicine (Ms Hebert) and Psychiatry (Dr Musselman), - University of Miami/Miller School of Medicine, Miami, Florida. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130815 -PL - United States -TA - Prim Care Companion CNS Disord -JT - The primary care companion for CNS disorders -JID - 101547532 -PMC - PMC3869617 -EDAT- 2014/01/07 06:00 -MHDA- 2014/01/07 06:01 -PMCR- 2013/01/01 -CRDT- 2014/01/07 06:00 -PHST- 2013/02/07 00:00 [received] -PHST- 2013/04/12 00:00 [accepted] -PHST- 2014/01/07 06:00 [entrez] -PHST- 2014/01/07 06:00 [pubmed] -PHST- 2014/01/07 06:01 [medline] -PHST- 2013/01/01 00:00 [pmc-release] -AID - 13r01511 [pii] -AID - 10.4088/PCC.13r01511 [doi] -PST - ppublish -SO - Prim Care Companion CNS Disord. 2013;15(4):PCC.13r01511. doi: - 10.4088/PCC.13r01511. Epub 2013 Aug 15. - -PMID- 20566965 -OWN - NLM -STAT- MEDLINE -DCOM- 20100722 -LR - 20220321 -IS - 1524-4539 (Electronic) -IS - 0009-7322 (Linking) -VI - 121 -IP - 24 -DP - 2010 Jun 22 -TI - Drug-coated balloons for the prevention of vascular restenosis. -PG - 2672-80 -LID - 10.1161/CIRCULATIONAHA.110.936922 [doi] -FAU - Gray, William A -AU - Gray WA -AD - Department of Medicine, Columbia University Medical Center, 161 Ft. Washington - Ave., New York, NY 10032, USA. wg2131@columbia.edu -FAU - Granada, Juan F -AU - Granada JF -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Circulation -JT - Circulation -JID - 0147763 -RN - P88XT4IS4D (Paclitaxel) -SB - IM -MH - Angioplasty, Balloon, Coronary/adverse effects/*methods -MH - Coronary Restenosis/*prevention & control -MH - Drug Delivery Systems/adverse effects/*methods -MH - Humans -MH - Paclitaxel/pharmacokinetics -MH - Treatment Outcome -RF - 55 -EDAT- 2010/06/23 06:00 -MHDA- 2010/07/23 06:00 -CRDT- 2010/06/23 06:00 -PHST- 2010/06/23 06:00 [entrez] -PHST- 2010/06/23 06:00 [pubmed] -PHST- 2010/07/23 06:00 [medline] -AID - 121/24/2672 [pii] -AID - 10.1161/CIRCULATIONAHA.110.936922 [doi] -PST - ppublish -SO - Circulation. 2010 Jun 22;121(24):2672-80. doi: 10.1161/CIRCULATIONAHA.110.936922. - -PMID- 19763071 -OWN - NLM -STAT- MEDLINE -DCOM- 20100201 -LR - 20161125 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 57 -IP - 4 -DP - 2009 Aug -TI - Cardiac CT in 2009. -PG - 495-509 -AB - Multislice computed tomography is an emerging diagnostic modality in cardiology - practice. Within the last decade a rapid technical evolution from 4-slice - scanners to 64-slice and meanwhile 320-slice scanners which faster gantry - rotation time has taken place. These advances as well as improved post-processing - tools account for a stabilization of image quality and allow assessing cardiac - structures with high spatial and temporal resolution. Moreover, dedicated - acquisition techniques have been employed to reduce radiation exposure to a - minimum. Today cardiac computed tomography is not only able to depict the - coronary arteries, but to get reliable information about cardiac function and - cardiac structure. This review focuses on present clinical indications and future - application of multi-slice computed tomography in clinical cardiology. -FAU - Burgstahler, C -AU - Burgstahler C -AD - Department of Internal Medicine, Division of Sports Medicine, - Eberhard-Karls-University, Tuebingen, Germany. - christof.burgstahler@med.uni-tuebingen.de -FAU - Brodoefel, H -AU - Brodoefel H -FAU - Schroeder, S -AU - Schroeder S -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -RN - 0 (Contrast Media) -SB - IM -MH - Contrast Media -MH - Coronary Angiography/*methods -MH - Coronary Artery Bypass -MH - Coronary Stenosis/diagnostic imaging -MH - Diagnosis, Differential -MH - Electrocardiography -MH - Forecasting -MH - Heart/*diagnostic imaging -MH - Heart Diseases/*diagnostic imaging -MH - Heart Rate -MH - Heart Valve Diseases/diagnostic imaging -MH - Humans -MH - Tomography, Spiral Computed/*methods/standards -MH - Tomography, X-Ray Computed/*methods -MH - Ventricular Function, Left -RF - 100 -EDAT- 2009/09/19 06:00 -MHDA- 2010/02/02 06:00 -CRDT- 2009/09/19 06:00 -PHST- 2009/09/19 06:00 [entrez] -PHST- 2009/09/19 06:00 [pubmed] -PHST- 2010/02/02 06:00 [medline] -PST - ppublish -SO - Minerva Cardioangiol. 2009 Aug;57(4):495-509. - -PMID- 21850540 -OWN - NLM -STAT- MEDLINE -DCOM- 20130507 -LR - 20211020 -IS - 1573-7322 (Electronic) -IS - 1382-4147 (Linking) -VI - 17 -IP - 4-5 -DP - 2012 Sep -TI - Cardiac remodeling and subcellular defects in heart failure due to myocardial - infarction and aging. -PG - 671-81 -LID - 10.1007/s10741-011-9278-7 [doi] -AB - Although several risk factors including hypertension, cardiac hypertrophy, - coronary artery disease, and diabetes are known to result in heart failure, - elderly subjects are more susceptible to myocardial infarction and more likely to - develop heart failure. This article is intended to discuss that cardiac - dysfunction in hearts failing due to myocardial infarction and aging is - associated with cardiac remodeling and defects in the subcellular organelles such - as sarcolemma (SL), sarcoplasmic reticulum (SR), and myofibrils. Despite some - differences in the pattern of heart failure due to myocardial infarction and - aging with respect to their etiology and sequence of events, evidence has been - presented to show that subcellular remodeling plays a critical role in the - occurrence of intracellular Ca(2+)-overload and development of cardiac - dysfunction in both types of failing heart. In particular, alterations in gene - expression for SL and SR proteins induce Ca(2+)-handling abnormalities in - cardiomyocytes, whereas those for myofibrillar proteins impair the interaction of - Ca(2+) with myofibrils in hearts failing due to myocardial infarction and aging. - In addition, different phosphorylation mechanisms, which regulate the activities - of Ca(2+)-cycling proteins in SL and SR membranes as well as Ca(2+)-binding - proteins in myofibrils, become defective in the failing heart. Accordingly, it is - suggested that subcellular remodeling involving defects in Ca(2+)-handling and - Ca(2+)-binding proteins as well as their regulatory mechanisms is intimately - associated with cardiac remodeling and heart failure due to myocardial infarction - and aging. -FAU - Dhalla, Naranjan S -AU - Dhalla NS -AD - Institute of Cardiovascular Sciences, St. Boniface General Hospital Research - Centre, 351 Tache Avenue, Winnipeg, MB, Canada. nsdhalla@sbrc.ca -FAU - Rangi, Shashanka -AU - Rangi S -FAU - Babick, Andrea P -AU - Babick AP -FAU - Zieroth, Shelley -AU - Zieroth S -FAU - Elimban, Vijayan -AU - Elimban V -LA - eng -GR - Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Aged -MH - Aging/*physiology -MH - Calcium/*metabolism -MH - Heart Failure/etiology/*metabolism -MH - Humans -MH - Myocardial Infarction/*complications/metabolism -MH - Myocardium/metabolism -MH - Ventricular Remodeling/*physiology -EDAT- 2011/08/19 06:00 -MHDA- 2013/05/08 06:00 -CRDT- 2011/08/19 06:00 -PHST- 2011/08/19 06:00 [entrez] -PHST- 2011/08/19 06:00 [pubmed] -PHST- 2013/05/08 06:00 [medline] -AID - 10.1007/s10741-011-9278-7 [doi] -PST - ppublish -SO - Heart Fail Rev. 2012 Sep;17(4-5):671-81. doi: 10.1007/s10741-011-9278-7. - -PMID- 20699674 -OWN - NLM -STAT- MEDLINE -DCOM- 20110602 -LR - 20250529 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Print) -IS - 1061-5377 (Linking) -VI - 18 -IP - 5 -DP - 2010 Sep-Oct -TI - Fish oil for the treatment of cardiovascular disease. -PG - 258-63 -LID - 10.1097/CRD.0b013e3181ea0de0 [doi] -AB - Omega-3 fatty acids, which are found abundantly in fish oil, are increasingly - being used in the management of cardiovascular disease. It is clear that fish - oil, in clinically used doses (typically 4 g/d of eicosapentaenoic acid and - docosahexaenoic acid) reduce high triglycerides. However, the role of omega-3 - fatty acids in reducing mortality, sudden death, arrhythmias, myocardial - infarction, and heart failure has not yet been established. This review will - focus on the current clinical uses of fish oil and provide an update on their - effects on triglycerides, coronary artery disease, heart failure, and arrhythmia. - We will explore the dietary sources of fish oil as compared with drug therapy, - and discuss the use of fish oil products in combination with other commonly used - lipid-lowering agents. We will examine the underlying mechanism of fish oil's - action on triglyceride reduction, plaque stability, and effect in diabetes, and - review the newly discovered anti-inflammatory effects of fish oil. Finally, we - will examine the limitations of current data and suggest recommendations for fish - oil use. -FAU - Weitz, Daniel -AU - Weitz D -AD - Department of Medicine, Leon H. Charney Division of Cardiology, NYU Langone - Medical Center, New York, NY 10016, USA. Weitz@nyumc.org -FAU - Weintraub, Howard -AU - Weintraub H -FAU - Fisher, Edward -AU - Fisher E -FAU - Schwartzbard, Arthur Z -AU - Schwartzbard AZ -LA - eng -GR - R01 HL058541/HL/NHLBI NIH HHS/United States -GR - R01 HL58541/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Fatty Acids, Omega-3) -RN - 0 (Fish Oils) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Hypolipidemic Agents) -RN - 0 (Triglycerides) -RN - U202363UOS (Fenofibrate) -SB - IM -MH - Arrhythmias, Cardiac/epidemiology/prevention & control -MH - Cardiovascular Diseases/*drug therapy/epidemiology/mortality -MH - Death, Sudden, Cardiac/epidemiology/prevention & control -MH - Diabetes Mellitus/epidemiology/prevention & control -MH - Fatty Acids, Omega-3/*therapeutic use -MH - Fenofibrate/therapeutic use -MH - Fish Oils/therapeutic use -MH - Heart Failure/epidemiology/prevention & control -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Hypolipidemic Agents/therapeutic use -MH - Triglycerides/metabolism -MH - United States/epidemiology -PMC - PMC3217043 -MID - NIHMS334672 -EDAT- 2010/08/12 06:00 -MHDA- 2011/06/03 06:00 -PMCR- 2011/11/15 -CRDT- 2010/08/12 06:00 -PHST- 2010/08/12 06:00 [entrez] -PHST- 2010/08/12 06:00 [pubmed] -PHST- 2011/06/03 06:00 [medline] -PHST- 2011/11/15 00:00 [pmc-release] -AID - 00045415-201009000-00006 [pii] -AID - 10.1097/CRD.0b013e3181ea0de0 [doi] -PST - ppublish -SO - Cardiol Rev. 2010 Sep-Oct;18(5):258-63. doi: 10.1097/CRD.0b013e3181ea0de0. - -PMID- 18835843 -OWN - NLM -STAT- MEDLINE -DCOM- 20090326 -LR - 20181113 -IS - 1755-3245 (Electronic) -IS - 0008-6363 (Print) -IS - 0008-6363 (Linking) -VI - 81 -IP - 3 -DP - 2009 Feb 15 -TI - Macro- and micronutrient dyshomeostasis in the adverse structural remodelling of - myocardium. -PG - 500-8 -LID - 10.1093/cvr/cvn261 [doi] -AB - Hypertension and heart failure are worldwide health problems of ever-increasing - proportions. A failure of the heart, during either systolic and/or diastolic - phases of the cardiac cycle, has its origins rooted in an adverse structural, - biochemical, and molecular remodelling of myocardium that involves its cellular - constituents, extracellular matrix, and intramural coronary vasculature. Herein - we focus on the pathogenic role of a dyshomeostasis of several macro- (i.e. - Ca(2+) and Mg(2+)) and micronutrients (i.e. Zn(2+), Se(2+), and vitamin D) in - contributing to adverse remodelling of the myocardium and its failure as a - pulsatile muscular pump. An improved understanding of how these macro- and - micronutrients account for the causes and consequences of adverse myocardial - remodelling carries with it the potential of identifying new biomarkers - predictive of risk, onset and progression, and response to intervention(s), which - could be monitored non-invasively and serially over time. Moreover, such - incremental knowledge will serve as the underpinning to the development of novel - strategies aimed at preventing and/or regressing the ongoing adverse remodelling - of myocardium. The time is at hand to recognize the importance of macro- and - micronutrient dyshomeostasis in the evaluation and management of hypertension and - heart failure. -FAU - Weber, Karl T -AU - Weber KT -AD - Division of Cardiovascular Diseases, University of Tennessee Health Science - Center, 920 Madison Ave., Suite 300, Memphis, TN 38163, USA. ktweber@utmem.edu -FAU - Weglicki, William B -AU - Weglicki WB -FAU - Simpson, Robert U -AU - Simpson RU -LA - eng -GR - R01-HL062282/HL/NHLBI NIH HHS/United States -GR - R01-HL065178/HL/NHLBI NIH HHS/United States -GR - R01-HL073043/HL/NHLBI NIH HHS/United States -GR - R01-HL074894/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20081003 -PL - England -TA - Cardiovasc Res -JT - Cardiovascular research -JID - 0077427 -RN - 0 (Biomarkers) -RN - 0 (Micronutrients) -RN - 1406-16-2 (Vitamin D) -RN - 789U1901C5 (Copper) -RN - H6241UJ22B (Selenium) -RN - I38ZP9992A (Magnesium) -RN - J41CSQ7QDS (Zinc) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Animals -MH - Biomarkers/metabolism -MH - Calcium/metabolism -MH - Copper/metabolism -MH - Disease Progression -MH - Heart Failure/etiology/*metabolism/physiopathology/therapy -MH - Homeostasis -MH - Humans -MH - Hypertension/complications/*metabolism/physiopathology/therapy -MH - Magnesium/metabolism -MH - Micronutrients/*metabolism -MH - Myocardium/enzymology/*metabolism -MH - Prognosis -MH - Selenium/metabolism -MH - *Ventricular Remodeling -MH - Vitamin D/metabolism -MH - Zinc/metabolism -PMC - PMC2639130 -EDAT- 2008/10/07 09:00 -MHDA- 2009/03/27 09:00 -PMCR- 2010/02/15 -CRDT- 2008/10/07 09:00 -PHST- 2008/10/07 09:00 [pubmed] -PHST- 2009/03/27 09:00 [medline] -PHST- 2008/10/07 09:00 [entrez] -PHST- 2010/02/15 00:00 [pmc-release] -AID - cvn261 [pii] -AID - 10.1093/cvr/cvn261 [doi] -PST - ppublish -SO - Cardiovasc Res. 2009 Feb 15;81(3):500-8. doi: 10.1093/cvr/cvn261. Epub 2008 Oct - 3. - -PMID- 20425242 -OWN - NLM -STAT- MEDLINE -DCOM- 20101005 -LR - 20211020 -IS - 1534-6242 (Electronic) -IS - 1523-3804 (Linking) -VI - 12 -IP - 2 -DP - 2010 Mar -TI - Does statin therapy affect the progression of atherosclerosis measured by a - coronary calcium score? -PG - 83-7 -LID - 10.1007/s11883-009-0073-z [doi] -AB - Coronary atherosclerosis is a leading cause of death in the United States and - worldwide, accounting for close to 1 million deaths annually in the United States - alone. The evaluation of coronary disease by CT-derived calcium scores is a - rapidly evolving field of medical imaging. Furthermore, until recently, whether - or not regression or progression of coronary disease could accurately be assessed - by coronary calcium scores had been a question of considerable debate among - experts in this field. If the medical treatment of coronary artery disease by - statin pharmacotherapy could be accurately assessed by coronary calcium scoring, - this would take much of the current guess work out of statin pharmacotherapy. - Initial retrospective studies and observational data suggested that statin - treatment resulted in reduction of coronary calcium. More recently, five - randomized controlled trials have demonstrated that not only does statin - treatment not reduce coronary calcium, but in fact, the progression of coronary - calcium by CT scanning is indistinguishable from placebo treatment. -FAU - Gill, Edward A Jr -AU - Gill EA Jr -AD - Harborview Medical Center, Seattle, WA 98104, USA. eagill@u.washington.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Atheroscler Rep -JT - Current atherosclerosis reports -JID - 100897685 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Atherosclerosis/diagnosis/*drug therapy/etiology -MH - Calcinosis/*complications/diagnosis/metabolism -MH - Calcium/*analysis -MH - Coronary Vessels/*metabolism -MH - Disease Progression -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Tomography, X-Ray Computed/*methods -MH - Treatment Outcome -EDAT- 2010/04/29 06:00 -MHDA- 2010/10/06 06:00 -CRDT- 2010/04/29 06:00 -PHST- 2010/04/29 06:00 [entrez] -PHST- 2010/04/29 06:00 [pubmed] -PHST- 2010/10/06 06:00 [medline] -AID - 10.1007/s11883-009-0073-z [doi] -PST - ppublish -SO - Curr Atheroscler Rep. 2010 Mar;12(2):83-7. doi: 10.1007/s11883-009-0073-z. - -PMID- 19426545 -OWN - NLM -STAT- MEDLINE -DCOM- 20090914 -LR - 20240317 -IS - 1471-2296 (Electronic) -IS - 1471-2296 (Linking) -VI - 10 -DP - 2009 May 9 -TI - Somatic diseases in patients with schizophrenia in general practice: their - prevalence and health care. -PG - 32 -LID - 10.1186/1471-2296-10-32 [doi] -AB - BACKGROUND: Schizophrenia patients frequently develop somatic co-morbidity. Core - tasks for GPs are the prevention and diagnosis of somatic diseases and the - provision of care for patients with chronic diseases. Schizophrenia patients - experience difficulties in recognizing and coping with their physical problems; - however GPs have neither specific management policies nor guidelines for the - diagnosis and treatment of somatic co-morbidity in schizophrenia patients. This - paper systematically reviews the prevalence and treatment of somatic co-morbidity - in schizophrenia patients in general practice. METHODS: The MEDLINE, EMBASE, - PsycINFO data-bases and the Cochrane Library were searched and original research - articles on somatic diseases of schizophrenia patients and their treatment in the - primary care setting were selected. RESULTS: The results of this search show that - the incidence of a wide range of diseases, such as diabetes mellitus, the - metabolic syndrome, coronary heart diseases, and COPD is significantly higher in - schizophrenia patients than in the normal population. The health of schizophrenic - patients is less than optimal in several areas, partly due to their inadequate - help-seeking behaviour. Current GP management of such patients appears not to - take this fact into account. However, when schizophrenic patients seek the GP's - help, they value the care provided. CONCLUSION: Schizophrenia patients are at - risk of undetected somatic co-morbidity. They present physical complaints at a - late, more serious stage. GPs should take this into account by adopting proactive - behaviour. The development of a set of guidelines with a clear description of the - GP's responsibilities would facilitate the desired changes in the management of - somatic diseases in these patients. -FAU - Oud, Marian J T -AU - Oud MJ -AD - Department of General Practice, University Medical Centre Groningen, University - of Groningen, Antonius Deusinglaan 1, 9713AV Groningen, The Netherlands. - m.j.t.oud@home.nl -FAU - Meyboom-de Jong, Betty -AU - Meyboom-de Jong B -LA - eng -PT - Journal Article -PT - Review -DEP - 20090509 -PL - England -TA - BMC Fam Pract -JT - BMC family practice -JID - 100967792 -SB - IM -MH - Cardiovascular Diseases/epidemiology/therapy -MH - Chronic Disease/*epidemiology/*therapy -MH - Comorbidity -MH - Diabetes Mellitus/epidemiology/therapy -MH - Family Practice/*methods -MH - Humans -MH - Metabolic Syndrome/epidemiology/therapy -MH - Neoplasms/epidemiology/therapy -MH - Prevalence -MH - Pulmonary Disease, Chronic Obstructive/epidemiology/therapy -MH - Schizophrenia/*epidemiology/*therapy -PMC - PMC2688496 -EDAT- 2009/05/12 09:00 -MHDA- 2009/09/15 06:00 -PMCR- 2009/05/09 -CRDT- 2009/05/12 09:00 -PHST- 2008/07/24 00:00 [received] -PHST- 2009/05/09 00:00 [accepted] -PHST- 2009/05/12 09:00 [entrez] -PHST- 2009/05/12 09:00 [pubmed] -PHST- 2009/09/15 06:00 [medline] -PHST- 2009/05/09 00:00 [pmc-release] -AID - 1471-2296-10-32 [pii] -AID - 10.1186/1471-2296-10-32 [doi] -PST - epublish -SO - BMC Fam Pract. 2009 May 9;10:32. doi: 10.1186/1471-2296-10-32. - -PMID- 24843641 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20220408 -IS - 2040-1116 (Print) -IS - 2040-1124 (Electronic) -IS - 2040-1116 (Linking) -VI - 4 -IP - 2 -DP - 2013 Mar 18 -TI - Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: - Incretin actions beyond the pancreas. -PG - 108-30 -LID - 10.1111/jdi.12065 [doi] -AB - Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 - (GLP-1) are the two primary incretin hormones secreted from the intestine on - ingestion of various nutrients to stimulate insulin secretion from pancreatic - β-cells glucose-dependently. GIP and GLP-1 undergo degradation by dipeptidyl - peptidase-4 (DPP-4), and rapidly lose their biological activities. The actions of - GIP and GLP-1 are mediated by their specific receptors, the GIP receptor (GIPR) - and the GLP-1 receptor (GLP-1R), which are expressed in pancreatic β-cells, as - well as in various tissues and organs. A series of investigations using mice - lacking GIPR and/or GLP-1R, as well as mice lacking DPP-4, showed involvement of - GIP and GLP-1 in divergent biological activities, some of which could have - implications for preventing diabetes-related microvascular complications (e.g., - retinopathy, nephropathy and neuropathy) and macrovascular complications (e.g., - coronary artery disease, peripheral artery disease and cerebrovascular disease), - as well as diabetes-related comorbidity (e.g., obesity, non-alcoholic fatty liver - disease, bone fracture and cognitive dysfunction). Furthermore, recent studies - using incretin-based drugs, such as GLP-1 receptor agonists, which stably - activate GLP-1R signaling, and DPP-4 inhibitors, which enhance both GLP-1R and - GIPR signaling, showed that GLP-1 and GIP exert effects possibly linked to - prevention or treatment of diabetes-related complications and comorbidities - independently of hyperglycemia. We review recent findings on the extrapancreatic - effects of GIP and GLP-1 on the heart, brain, kidney, eye and nerves, as well as - in the liver, fat and several organs from the perspective of diabetes-related - complications and comorbidities. -FAU - Seino, Yutaka -AU - Seino Y -AD - Kansai Electric Power Hospital. -FAU - Yabe, Daisuke -AU - Yabe D -AD - Division of Diabetes Clinical Nutrition and Endocrinology Kansai Electric Power - Hospital Osaka Japan. -LA - eng -PT - Journal Article -PT - Review -PL - Japan -TA - J Diabetes Investig -JT - Journal of diabetes investigation -JID - 101520702 -PMC - PMC4019264 -OTO - NOTNLM -OT - Diabetic complication -OT - Glucagon‐like peptide‐1 -OT - Glucose‐dependent insulinotropic polypeptide -EDAT- 2013/03/18 00:00 -MHDA- 2013/03/18 00:01 -PMCR- 2013/03/18 -CRDT- 2014/05/21 06:00 -PHST- 2013/01/16 00:00 [received] -PHST- 2013/01/24 00:00 [accepted] -PHST- 2014/05/21 06:00 [entrez] -PHST- 2013/03/18 00:00 [pubmed] -PHST- 2013/03/18 00:01 [medline] -PHST- 2013/03/18 00:00 [pmc-release] -AID - JDI12065 [pii] -AID - 10.1111/jdi.12065 [doi] -PST - ppublish -SO - J Diabetes Investig. 2013 Mar 18;4(2):108-30. doi: 10.1111/jdi.12065. - -PMID- 22303530 -OWN - NLM -STAT- MEDLINE -DCOM- 20140428 -LR - 20220409 -IS - 0048-7449 (Print) -IS - 0048-7449 (Linking) -VI - 63 -IP - 4 -DP - 2012 Jan 19 -TI - Clinical features of gout. -PG - 238-45 -LID - 10.4081/reumatismo.2011.238 [doi] -AB - Gout is a metabolic disease characterized by hyperuricemia and the deposition of - monosodium urate (MSU) crystals in the joints and soft tissues, consisting of a - self-limited acute phase characterized by recurrent attacks of synovitis and a - chronic phase in which inflammatory and structural changes of the joints and - periarticular tissues may lead to persistent symptoms. Acute gout is - characterized by a sudden monoarthritis of rapid onset, with intense pain, mostly - affecting the big toe (50% of initial attacks), the foot, ankle, midtarsal, knee, - wrist, finger, and elbow. Acute flares also occur in periarticular structures, - including bursae and tendons. The presence of characteristic MSU crystals in the - joint fluid, appearing needle-like and showing strong negative birefringence by - polarized microscopy, is pivotal to confirm the diagnosis of gout. The time - interval separating the first attack from subsequent episodes of acute synovitis - may be widely variable, ranging from a few days to several years. During the - period between acute attacks the patient is asymptomatic even if MSU deposition - may continue to increase silently. The factors that control the rate, location, - and degree of ongoing deposition in gouty patients are not well defined. Chronic - gout is the natural evolution of untreated hyperuricemia in patients with gouty - attacks followed by pain-free intercritical periods. It is characterized by the - deposition of solid MSU crystal aggregates in a variety of tissues including - joints, bursae and tendons. Tophi can occur in a variety of locations including - the helix of the ear, olecranon bursa, and over the interphalangeal joints. Their - development is usually related with both the degree and the duration of - hyperuricemia. About 20% of patients with gout have urinary tract stones and can - develop an interstitial urate nephropathy. There is a strong association between - hyperuricaemia and the metabolic syndrome (the constellation of insulin - resistance, hypertension, obesity and dyslipidaemia), and gouty patients often - have a medical history of kidney disease, diabetes mellitus and signs of vascular - illness such as coronary artery disease, heart failure and stroke, resulting with - a poor overall quality of life. -FAU - Grassi, W -AU - Grassi W -AD - Clinica Reumatologica, Università Politecnica delle Marche, Ancona, Italy. - walter.grassi@univpm.it -FAU - De Angelis, R -AU - De Angelis R -LA - eng -PT - Journal Article -PT - Review -DEP - 20120119 -PL - Italy -TA - Reumatismo -JT - Reumatismo -JID - 0401302 -RN - 0 (Biomarkers) -RN - 268B43MJ25 (Uric Acid) -SB - IM -MH - Acute Disease -MH - Arthritis, Gouty/diagnosis -MH - Biomarkers/metabolism -MH - Chronic Disease -MH - Crystallization -MH - Diagnosis, Differential -MH - Gout/*diagnosis/etiology/metabolism -MH - Humans -MH - Hyperuricemia/*diagnosis/metabolism -MH - Joints/metabolism -MH - Quality of Life -MH - Risk Factors -MH - Synovial Fluid/metabolism -MH - Uric Acid/*metabolism -EDAT- 2012/02/04 06:00 -MHDA- 2014/04/29 06:00 -CRDT- 2012/02/04 06:00 -PHST- 2012/01/19 00:00 [received] -PHST- 2012/01/19 00:00 [accepted] -PHST- 2012/02/04 06:00 [entrez] -PHST- 2012/02/04 06:00 [pubmed] -PHST- 2014/04/29 06:00 [medline] -AID - reumatismo.2011.238 [pii] -AID - 10.4081/reumatismo.2011.238 [doi] -PST - epublish -SO - Reumatismo. 2012 Jan 19;63(4):238-45. doi: 10.4081/reumatismo.2011.238. - -PMID- 20090429 -OWN - NLM -STAT- MEDLINE -DCOM- 20100303 -LR - 20100121 -IS - 1536-3686 (Electronic) -IS - 1075-2765 (Linking) -VI - 17 -IP - 1 -DP - 2010 Jan-Feb -TI - Role of angiotensin-converting enzyme inhibitors in vascular modulation: beyond - the hypertensive effects. -PG - e11-23 -LID - 10.1097/MJT.0b013e31815addd9 [doi] -AB - Angiotensin-converting enzyme (ACE) inhibitors are being widely used as - antihypertensives by clinicians worldwide. One in every three Americans has - hypertension. Hypertension, diabetes, obesity, active smoking, - hypercholesterolemia, and inactivity are the major cardiovascular risk factors, - which can produce compounding effects on human health, leading to cardiovascular - morbidity and mortality. We review the mechanism of action of ACE inhibitors and - explain the rationale for using ACE inhibitors not only in hypertensive patients - but also in patients with congestive heart failure, acute myocardial infarction, - or coronary artery disease. ACE inhibitors can reduce preload and afterload on - the heart, prevent ventricular remodeling, and even retard atherogenic changes in - the vessel walls. ACE inhibitors can also be helpful in slowing the progression - of kidney disease, especially in diabetics. Some studies such as the Heart - Outcomes Prevention Evaluation study have shown that ACE inhibitors can reduce - the risk of cardiovascular morbidity and mortality, particularly in high-risk - individuals. The renin-angiotensin-aldosterone system plays an important role in - regulating blood pressure and body volume in the human body. ACE inhibitors and - angiotensin-receptor blockers are the two classes of antihypertensives that - primarily act on the renin-angiotensin-aldosterone system. We discuss randomized, - controlled trials that evaluated different ACE inhibitors and compare them with - angiotensin-receptor blockers. -FAU - Katragadda, Srikanth -AU - Katragadda S -AD - Department of Medicine, Chicago Medical School, North Chicago, IL, USA. -FAU - Arora, Rohit R -AU - Arora RR -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - United States -TA - Am J Ther -JT - American journal of therapeutics -JID - 9441347 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/pharmacology/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/*pharmacology/therapeutic use -MH - Antihypertensive Agents/pharmacology/therapeutic use -MH - Heart Diseases/*drug therapy/physiopathology -MH - Humans -MH - Hypertension/*drug therapy/epidemiology/physiopathology -MH - Randomized Controlled Trials as Topic -MH - Renin-Angiotensin System/drug effects -MH - Risk Factors -MH - United States/epidemiology -RF - 55 -EDAT- 2010/01/22 06:00 -MHDA- 2010/03/04 06:00 -CRDT- 2010/01/22 06:00 -PHST- 2010/01/22 06:00 [entrez] -PHST- 2010/01/22 06:00 [pubmed] -PHST- 2010/03/04 06:00 [medline] -AID - 00045391-201001000-00018 [pii] -AID - 10.1097/MJT.0b013e31815addd9 [doi] -PST - ppublish -SO - Am J Ther. 2010 Jan-Feb;17(1):e11-23. doi: 10.1097/MJT.0b013e31815addd9. - -PMID- 16375625 -OWN - NLM -STAT- MEDLINE -DCOM- 20060803 -LR - 20071115 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Linking) -VI - 4 -IP - 1 -DP - 2006 Jan -TI - Aortic stenosis and the failing heart. -PG - 25-31 -AB - The combination of aortic stenosis and left-ventricular dysfunction is a - challenging situation for the physician. Diagnosis of this condition requires a - detailed evaluation to understand the etiology and reversibility of the - ventricular dysfunction and to accurately determine the real severity of the - stenosis. Whether the aortic stenosis the cause of the left ventricular failure - or is an independent disease has significant diagnostic, prognostic and - therapeutic implications. Dobutamine echocardiography provides critical - information to determine the real severity and the left ventricle's potential to - recover (contractile reserve). Attempts to delay the progression of the aortic - stenosis with medical treatment have been limited, and valve replacement remains - the hallmark of ultimate treatment. If surgery is inadvertently delayed, left - ventricular systolic dysfunction will result in clinically evident congestive - heart failure and this situation carries a very high short-term mortality. Aortic - valve replacement in this setting improves the outcome, but perioperative - mortality is high, and particularly when coronary revascularization is also - needed, there is no ventricular contractile reserve and transvalvular gradients - are low. Adequate timing of surgery is extremely important and increasingly more - difficult. Management decisions should be tailored by the results of dobutamine - echocardiography and made on a case-by-case basis. -FAU - Asch, Federico M -AU - Asch FM -AD - Washinton Hospital Center, Washington, DC 20010-2975, USA. - neil.j.weissman@medstar.net -FAU - Weissman, Neil J -AU - Weissman NJ -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -SB - IM -MH - Animals -MH - Aortic Valve Stenosis/complications/*diagnosis/surgery -MH - Echocardiography/methods -MH - Heart Failure/complications/*diagnosis/surgery -MH - Heart Valve Prosthesis Implantation/methods -MH - Humans -MH - Ventricular Dysfunction, Left/complications/*diagnosis/surgery -RF - 35 -EDAT- 2005/12/27 09:00 -MHDA- 2006/08/04 09:00 -CRDT- 2005/12/27 09:00 -PHST- 2005/12/27 09:00 [pubmed] -PHST- 2006/08/04 09:00 [medline] -PHST- 2005/12/27 09:00 [entrez] -AID - 10.1586/14779072.4.1.25 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2006 Jan;4(1):25-31. doi: 10.1586/14779072.4.1.25. - -PMID- 24144531 -OWN - NLM -STAT- MEDLINE -DCOM- 20150514 -LR - 20220409 -IS - 1473-0480 (Electronic) -IS - 0306-3674 (Linking) -VI - 48 -IP - 16 -DP - 2014 Aug -TI - High-intensity interval training in patients with lifestyle-induced - cardiometabolic disease: a systematic review and meta-analysis. -PG - 1227-34 -LID - 10.1136/bjsports-2013-092576 [doi] -AB - BACKGROUND/AIM: Cardiorespiratory fitness (CRF) is a strong determinant of - morbidity and mortality. In athletes and the general population, it is - established that high-intensity interval training (HIIT) is superior to - moderate-intensity continuous training (MICT) in improving CRF. This is a - systematic review and meta-analysis to quantify the efficacy and safety of HIIT - compared to MICT in individuals with chronic cardiometabolic lifestyle diseases. - METHODS: The included studies were required to have a population sample of - chronic disease, where poor lifestyle is considered as a main contributor to the - disease. The procedural quality of the studies was assessed by use of a modified - Physiotherapy Evidence Base Database (PEDro) scale. A meta-analysis compared the - mean difference (MD) of preintervention versus postintervention CRF (VO2peak) - between HIIT and MICT. RESULTS: 10 studies with 273 patients were included in the - meta-analysis. Participants had coronary artery disease, heart failure, - hypertension, metabolic syndrome and obesity. There was a significantly higher - increase in the VO2peak after HIIT compared to MICT (MD 3.03 mL/kg/min, 95% CI - 2.00 to 4.07), equivalent to 9.1%. CONCLUSIONS: HIIT significantly increases CRF - by almost double that of MICT in patients with lifestyle-induced chronic - diseases. -CI - Published by the BMJ Publishing Group Limited. For permission to use (where not - already granted under a licence) please go to - http://group.bmj.com/group/rights-licensing/permissions. -FAU - Weston, Kassia S -AU - Weston KS -AD - School of Human Movement Studies, The University of Queensland, St Lucia, - Brisbane, Queensland, Australia. -FAU - Wisløff, Ulrik -AU - Wisløff U -AD - Department of Circulation and Medical Imaging, Faculty of Medicine, KG Jebsen - Center of Exercise in Medicine at Norwegian University of Science and Technology, - Trondheim, Norway. -FAU - Coombes, Jeff S -AU - Coombes JS -AD - School of Human Movement Studies, The University of Queensland, St Lucia, - Brisbane, Queensland, Australia. -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PT - Systematic Review -DEP - 20131021 -PL - England -TA - Br J Sports Med -JT - British journal of sports medicine -JID - 0432520 -RN - 0 (Antioxidants) -SB - IM -MH - Antioxidants/metabolism -MH - *Cardiac Rehabilitation -MH - Chronic Disease -MH - Exercise Therapy/*methods -MH - Humans -MH - Life Style -MH - Metabolic Diseases/*rehabilitation -MH - Oxygen Consumption/physiology -MH - Patient Compliance -MH - Quality of Life -MH - Risk Factors -MH - Treatment Outcome -OTO - NOTNLM -OT - Aerobic Fitness/Vo2 Max -OT - Cardiovascular -OT - Exercise Physiology -OT - Statistical Review -EDAT- 2013/10/23 06:00 -MHDA- 2015/05/15 06:00 -CRDT- 2013/10/23 06:00 -PHST- 2013/10/23 06:00 [entrez] -PHST- 2013/10/23 06:00 [pubmed] -PHST- 2015/05/15 06:00 [medline] -AID - bjsports-2013-092576 [pii] -AID - 10.1136/bjsports-2013-092576 [doi] -PST - ppublish -SO - Br J Sports Med. 2014 Aug;48(16):1227-34. doi: 10.1136/bjsports-2013-092576. Epub - 2013 Oct 21. - -PMID- 23007816 -OWN - NLM -STAT- MEDLINE -DCOM- 20131202 -LR - 20120925 -IS - 1972-6007 (Electronic) -IS - 0009-9074 (Linking) -VI - 163 -IP - 4 -DP - 2012 Jul -TI - [Atheroembolism renal disease: diagnosis and etiologic factors]. -PG - 313-22 -AB - Atheromatous renal disease is the major cause of renal insufficiency in the - elderly, and cholesterol embolism is a manifestation of this disease. Cholesterol - embolism occurs in patients suffering from diffuse erosive atherosclerosis, - usually after triggering causes, such as aortic surgery, arterial invasive - procedures (angiography, left heart catheterization and coronary angioplasty) and - anticoagulant or thrombolytic therapy. It is characterized by occlusion of small - arteries with cholesterol emboli deriving from eroded atheromatous plaques of the - aorta or large feeder arteries. The proximity of the kidneys to the abdominal - aorta and the large renal blood supply make the kidney a frequent target organ - for cholesterol atheroembolism. The exact incidence of atheroembolic renal - disease (AERD) is not known. The reported incidence AERD varied in the literature - because of the differences in study design and the different criteria used for - making the diagnosis. Retrospective data derived from autopsy or biopsy studies - may exaggerate the frequency by including many subclinical cases. Clinical - observations that are based on a short duration of follow-up after an invasive - vascular procedure and the infrequency of the confirmatory renal biopsies can - lead to an underestimation of the true incidence of AERD. The initial signs and - symptoms in patients diagnosed with cholesterol embolism were blue toes syndrome, - livedo reticularis, gangrene, leg, toe or foot pain, abdominal pain and flank or - back pain, gross haematuria, accelerated hypertension and renal failure. - Cholesterol embolism may also be associated with fever, increased erythrocyte - sedimentation rate and eosinophilia. Thus, in the cases of spontaneous - cholesterol embolism, differential diagnosis includes, polyarteritis nodosa, - allergic vasculitis and subacute bacterial endocarditis. Skin and renal biopsy - specimens are the best sample for histologic diagnosis. There is, at present, no - pharmacological treatments shown to be effective in altering the course of the - disease. Management is limited to supportive therapy and avoidance of - anticoagulation; aortic procedures should be postponed. -FAU - Granata, A -AU - Granata A -AD - U.O.C. Nefrologia Dialisi e Cardiologia, Ospedale "San Giovanni di Dio" ASP1, - Agrigento, Italia. antonio.granata4@tin.it -FAU - Insalaco, M -AU - Insalaco M -FAU - Di Pietro, F -AU - Di Pietro F -FAU - Di Rosa, S -AU - Di Rosa S -FAU - Romano, G -AU - Romano G -FAU - Scuderi, R -AU - Scuderi R -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - La malattia renale ateroembolica: diagnosi ed eziologia. -PL - Italy -TA - Clin Ter -JT - La Clinica terapeutica -JID - 0372604 -SB - IM -MH - Embolism, Cholesterol/*complications/*diagnosis/therapy -MH - Humans -MH - Kidney Diseases/*etiology/therapy -MH - Prognosis -EDAT- 2012/09/26 06:00 -MHDA- 2013/12/16 06:00 -CRDT- 2012/09/26 06:00 -PHST- 2012/09/26 06:00 [entrez] -PHST- 2012/09/26 06:00 [pubmed] -PHST- 2013/12/16 06:00 [medline] -PST - ppublish -SO - Clin Ter. 2012 Jul;163(4):313-22. - -PMID- 20695882 -OWN - NLM -STAT- MEDLINE -DCOM- 20110224 -LR - 20101122 -IS - 1365-2362 (Electronic) -IS - 0014-2972 (Linking) -VI - 40 -IP - 12 -DP - 2010 Dec -TI - The versatility of HDL: a crucial anti-inflammatory regulator. -PG - 1131-43 -LID - 10.1111/j.1365-2362.2010.02361.x [doi] -AB - BACKGROUND: Low levels of plasma high-density lipoprotein (HDL) represent a major - cardiovascular risk factor and therefore raising HDL has been proposed to - positively affect patients with atherosclerotic heart disease. However, the - current evidence that raising HDL per se will reduce atherosclerosis and thereby - cardiovascular events still remains controversial. AIMS: In this review, we - discuss the diverse anti-atherogenic and anti-inflammatory properties of HDL in - the light of recent findings indicating that the quality rather than the mere - quantity of HDL determines its beneficial effects against atherosclerosis. More - specifically, we will focus on the conspicuous anti-inflammatory properties of - HDL as this might contribute to the overall beneficial effects of HDL in diseased - patients such as modulation of costimulatory/adhesion molecule expression, - cytokine production and inhibition of the prototypical proinflammatory - transcription factor NF-κB. RESULTS: A range of clinical disorders share - permanent inflammation as a characteristic hallmark including coronary artery - disease, chronic kidney disease, diabetes mellitus or rheumatoid arthritis and - also display distinct qualitative changes in the HDL compartment. Loss of - anti-inflammatory functions of HDL is emerging as an important risk factor for - disease progression and survival in these clinical entities. CONCLUSIONS: It will - be important to define the anti-inflammatory effects of HDL at the molecular - level and to dissect the manifold functional implications to develop both novel - functional assays that enable meaningful outcome studies and foster new - therapeutic concepts in patients with altered HDL function. -CI - © 2010 The Authors. European Journal of Clinical Investigation © 2010 Stichting - European Society for Clinical Investigation Journal Foundation. -FAU - Säemann, Marcus D -AU - Säemann MD -AD - Department of Internal Medicine III, Division of Nephrology and Dialysis, Medical - University Vienna, Währinger Gürtel, Vienna, Austria. - marcus.saemann@meduniwien.ac.at -FAU - Poglitsch, Marko -AU - Poglitsch M -FAU - Kopecky, Chantal -AU - Kopecky C -FAU - Haidinger, Michael -AU - Haidinger M -FAU - Hörl, Walter H -AU - Hörl WH -FAU - Weichhart, Thomas -AU - Weichhart T -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Eur J Clin Invest -JT - European journal of clinical investigation -JID - 0245331 -RN - 0 (Hypolipidemic Agents) -RN - 0 (Lipoproteins, HDL) -SB - IM -MH - Atherosclerosis/*drug therapy/physiopathology -MH - Cardiovascular Diseases/*prevention & control -MH - Chronic Disease -MH - Endothelium, Vascular/physiology -MH - Humans -MH - Hypolipidemic Agents/therapeutic use -MH - Inflammation/drug therapy/physiopathology -MH - Lipoproteins, HDL/chemistry/*physiology -EDAT- 2010/08/11 06:00 -MHDA- 2011/02/25 06:00 -CRDT- 2010/08/11 06:00 -PHST- 2010/08/11 06:00 [entrez] -PHST- 2010/08/11 06:00 [pubmed] -PHST- 2011/02/25 06:00 [medline] -AID - ECI2361 [pii] -AID - 10.1111/j.1365-2362.2010.02361.x [doi] -PST - ppublish -SO - Eur J Clin Invest. 2010 Dec;40(12):1131-43. doi: - 10.1111/j.1365-2362.2010.02361.x. - -PMID- 16585666 -OWN - NLM -STAT- MEDLINE -DCOM- 20060421 -LR - 20190619 -IS - 1539-3704 (Electronic) -IS - 0003-4819 (Linking) -VI - 144 -IP - 7 -DP - 2006 Apr 4 -TI - Adiposity of the heart, revisited. -PG - 517-24 -AB - Obesity is a major risk factor for heart disease. In the face of obesity's - growing prevalence, it is important for physicians to be aware of emerging - research of novel mechanisms through which adiposity adversely affects the heart. - Conventional wisdom suggests that either hemodynamic (that is, increased cardiac - output and hypertension) or metabolic (that is, dyslipidemic) derangements - associated with obesity may predispose individuals to coronary artery disease and - heart failure. The purpose of this review is to highlight a novel mechanism for - heart disease in obesity whereby excessive lipid accumulation within the - myocardium is directly cardiotoxic and causes left ventricular remodeling and - dilated cardiomyopathy. Studies in animal models of obesity reveal that - intracellular accumulation of triglyceride renders organs dysfunctional, which - leads to several well-recognized clinical syndromes related to obesity (including - type 2 diabetes). In these rodent models, excessive lipid accumulation in the - myocardium causes left ventricular hypertrophy and nonischemic, dilated - cardiomyopathy. Novel magnetic resonance spectroscopy techniques are now - available to quantify intracellular lipid content in the myocardium and various - other human tissues, which has made it possible to translate these studies into a - clinical setting. By using this technology, we have recently begun to study the - role of myocardial steatosis in the development of obesity-specific - cardiomyopathy in humans. Recent studies in healthy individuals and patients with - heart failure reveal that myocardial lipid content increases with the degree of - adiposity and may contribute to the adverse structural and functional cardiac - adaptations seen in obese persons. These studies parallel the observations in - obese animals and provide evidence that myocardial lipid content may be a - biomarker and putative therapeutic target for cardiac disease in obese patients. -FAU - McGavock, Jonathan M -AU - McGavock JM -AD - University of Texas Southwestern Medical Center, Dallas, Texas 75390-8899, USA. -FAU - Victor, Ronald G -AU - Victor RG -FAU - Unger, Roger H -AU - Unger RH -FAU - Szczepaniak, Lidia S -AU - Szczepaniak LS -CN - American College of Physicians and the American Physiological Society -LA - eng -GR - K-25 HL-68736/HL/NHLBI NIH HHS/United States -GR - M01-RR00633/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - United States -TA - Ann Intern Med -JT - Annals of internal medicine -JID - 0372351 -SB - IM -CIN - Ann Intern Med. 2006 Oct 3;145(7):553-4; author reply 555. doi: - 10.7326/0003-4819-145-7-200610030-00018. PMID: 17015876 -CIN - Ann Intern Med. 2006 Oct 3;145(7):554-5; author reply 555. doi: - 10.7326/0003-4819-145-7-200610030-00021. PMID: 17015879 -CIN - Ann Intern Med. 2006 Oct 3;145(7):554; author reply 555. doi: - 10.7326/0003-4819-145-7-200610030-00020. PMID: 17015880 -CIN - Ann Intern Med. 2006 Oct 3;145(7):554; author reply 555. doi: - 10.7326/0003-4819-145-7-200610030-00019. PMID: 17015881 -MH - Animals -MH - Cardiomyopathy, Dilated/*etiology/metabolism -MH - Humans -MH - Hypertrophy, Left Ventricular/*etiology/metabolism -MH - *Lipid Metabolism -MH - Myocardium/*metabolism -MH - Obesity/*complications/*metabolism -RF - 43 -EDAT- 2006/04/06 09:00 -MHDA- 2006/04/25 09:00 -CRDT- 2006/04/06 09:00 -PHST- 2006/04/06 09:00 [pubmed] -PHST- 2006/04/25 09:00 [medline] -PHST- 2006/04/06 09:00 [entrez] -AID - 144/7/517 [pii] -AID - 10.7326/0003-4819-144-7-200604040-00011 [doi] -PST - ppublish -SO - Ann Intern Med. 2006 Apr 4;144(7):517-24. doi: - 10.7326/0003-4819-144-7-200604040-00011. - -PMID- 21829898 -OWN - NLM -STAT- MEDLINE -DCOM- 20120523 -LR - 20190606 -IS - 1414-431X (Electronic) -IS - 0100-879X (Linking) -VI - 44 -IP - 9 -DP - 2011 Sep -TI - Remodeling in the ischemic heart: the stepwise progression for heart failure. -PG - 890-8 -LID - S0100-879X2011007500096 [pii] -AB - Coronary artery disease is the leading cause of death in the developed world and - in developing countries. Acute mortality from acute myocardial infarction (MI) - has decreased in the last decades. However, the incidence of heart failure (HF) - in patients with healed infarcted areas is increasing. Therefore, HF prevention - is a major challenge to the health system in order to reduce healthcare costs and - to provide a better quality of life. Animal models of ischemia and infarction - have been essential in providing precise information regarding cardiac - remodeling. Several of these changes are maladaptive, and they progressively lead - to ventricular dilatation and predispose to the development of arrhythmias, HF - and death. These events depend on cell death due to necrosis and apoptosis and on - activation of the inflammatory response soon after MI. Systemic and local - neurohumoral activation has also been associated with maladaptive cardiac - remodeling, predisposing to HF. In this review, we provide a timely description - of the cardiovascular alterations that occur after MI at the cellular, - neurohumoral and electrical level and discuss the repercussions of these - alterations on electrical, mechanical and structural dysfunction of the heart. We - also identify several areas where insufficient knowledge limits the adoption of - better strategies to prevent HF development in chronically infarcted individuals. -FAU - Mill, J G -AU - Mill JG -AD - Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, - Vitória, ES, Brasil. -FAU - Stefanon, I -AU - Stefanon I -FAU - dos Santos, L -AU - dos Santos L -FAU - Baldo, M P -AU - Baldo MP -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110805 -PL - Brazil -TA - Braz J Med Biol Res -JT - Brazilian journal of medical and biological research = Revista brasileira de - pesquisas medicas e biologicas -JID - 8112917 -RN - 0 (Angiotensins) -RN - 0 (Inflammation Mediators) -RN - 4964P6T9RB (Aldosterone) -SB - IM -MH - Adrenergic Neurons/physiology -MH - Aldosterone/physiology -MH - Angiotensins/metabolism -MH - Apoptosis/physiology -MH - Arrhythmias, Cardiac/etiology -MH - Heart/*physiopathology -MH - Heart Failure/*etiology/prevention & control -MH - Humans -MH - Inflammation Mediators/metabolism -MH - Myocardial Infarction/*complications -MH - Myocardial Ischemia/metabolism/*physiopathology -MH - Myocardium/metabolism -MH - Myocytes, Cardiac/physiology -MH - Renin-Angiotensin System/physiology -MH - Sympathetic Nervous System/physiology -MH - Time Factors -EDAT- 2011/08/11 06:00 -MHDA- 2012/05/24 06:00 -CRDT- 2011/08/11 06:00 -PHST- 2011/02/13 00:00 [received] -PHST- 2011/07/26 00:00 [accepted] -PHST- 2011/08/11 06:00 [entrez] -PHST- 2011/08/11 06:00 [pubmed] -PHST- 2012/05/24 06:00 [medline] -AID - S0100-879X2011007500096 [pii] -AID - 10.1590/s0100-879x2011007500096 [doi] -PST - ppublish -SO - Braz J Med Biol Res. 2011 Sep;44(9):890-8. doi: 10.1590/s0100-879x2011007500096. - Epub 2011 Aug 5. - -PMID- 22143284 -OWN - NLM -STAT- MEDLINE -DCOM- 20120214 -LR - 20111206 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 20 -IP - 1 -DP - 2012 Jan-Feb -TI - Vitamin D: a cardioprotective agent? -PG - 38-44 -LID - 10.1097/CRD.0b013e31822c5380 [doi] -AB - Vitamin D is a fat-soluble vitamin that is naturally found in very few foods, is - added to others, and is available as a dietary supplement. It is produced - endogenously when ultraviolet light strikes the skin. Recent epidemiologic and - experimental evidence has suggested that low vitamin D levels may play a role in - various cardiovascular conditions, including coronary artery disease, congestive - heart failure, valvular calcification, stroke, hypertension, and cognitive - decline. Low vitamin D may lead to vascular smooth muscle cell proliferation, - endothelial cell dysfunction, vascular and myocardial cell calcification, and - increased inflammation. However, the data supporting a cardioprotective effect of - vitamin D supplementation are very weak, and the large, controlled clinical - trials now in progress should resolve this issue. -FAU - Liss, Yaakov -AU - Liss Y -AD - Department of Internal Medicine, Mt. Sinai Medical Center, New York, NY, USA. -FAU - Frishman, William H -AU - Frishman WH -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Cardiovascular Agents) -RN - 0 (Vitamins) -RN - 1406-16-2 (Vitamin D) -SB - IM -MH - Cardiovascular Agents/*administration & dosage -MH - Cardiovascular Diseases/etiology/*prevention & control -MH - *Dietary Supplements -MH - Humans -MH - Randomized Controlled Trials as Topic -MH - Risk Factors -MH - Secondary Prevention -MH - Vitamin D/*administration & dosage -MH - Vitamin D Deficiency/*complications/diet therapy -MH - Vitamins/*administration & dosage -EDAT- 2011/12/07 06:00 -MHDA- 2012/02/15 06:00 -CRDT- 2011/12/07 06:00 -PHST- 2011/12/07 06:00 [entrez] -PHST- 2011/12/07 06:00 [pubmed] -PHST- 2012/02/15 06:00 [medline] -AID - 00045415-201201000-00007 [pii] -AID - 10.1097/CRD.0b013e31822c5380 [doi] -PST - ppublish -SO - Cardiol Rev. 2012 Jan-Feb;20(1):38-44. doi: 10.1097/CRD.0b013e31822c5380. - -PMID- 18524729 -OWN - NLM -STAT- MEDLINE -DCOM- 20080813 -LR - 20080605 -IS - 1308-0032 (Electronic) -IS - 1302-8723 (Linking) -VI - 8 -IP - 3 -DP - 2008 Jun -TI - [Statins in stroke prevention]. -PG - 217-22 -AB - Cholesterol lowering with statins has been proven to reduce vascular events in - primary and secondary prevention of coronary artery disease (CAD). Epidemiologic - studies found no or little association between blood cholesterol levels and - stroke. However, randomized trials in patients with CAD have shown that statins - decrease stroke incidence. These statin trials indicate 21% relative risk - reductions for stroke. In subgroup analysis of the Heart Protection Study, - simvastatin had no effect on stroke recurrence, in patients with a previous - stroke. Recently, Stroke Prevention by Aggressive Reduction in Cholesterol Levels - study showed that treatment with high dose atorvastatin reduced risk of stroke in - patients with recent stroke and transient ischemic attack and no known CAD. In - this review, we will discuss the effects of statins on stroke and the potential - mechanisms of action. -FAU - Gedikli, Omer -AU - Gedikli O -AD - Karadeniz Teknik Universitesi Tip Fakültesi, Kardiyoloji Anabilim Dali, Trabzon, - Türkiye. omergedikli@yahoo.com -FAU - Baykan, Merih -AU - Baykan M -LA - tur -PT - English Abstract -PT - Journal Article -PT - Review -TT - Inmenin önlenmesinde statinler. -PL - Turkey -TA - Anadolu Kardiyol Derg -JT - Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology -JID - 101095069 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Ischemic Attack, Transient/*prevention & control -MH - Randomized Controlled Trials as Topic -RF - 50 -EDAT- 2008/06/06 09:00 -MHDA- 2008/08/14 09:00 -CRDT- 2008/06/06 09:00 -PHST- 2008/06/06 09:00 [pubmed] -PHST- 2008/08/14 09:00 [medline] -PHST- 2008/06/06 09:00 [entrez] -PST - ppublish -SO - Anadolu Kardiyol Derg. 2008 Jun;8(3):217-22. - -PMID- 19370327 -OWN - NLM -STAT- MEDLINE -DCOM- 20090706 -LR - 20211020 -IS - 1615-6692 (Electronic) -IS - 0340-9937 (Linking) -VI - 34 -IP - 2 -DP - 2009 Mar -TI - [Surgery or medical therapy for secondary mitral regurgitation?]. -PG - 118-23 -LID - 10.1007/s00059-009-3198-5 [doi] -AB - Mitral regurgitation (MR) is the second most frequent valve disease in Europe. In - addressing the current therapy for MR, it is useful to distinguish primary from - secondary or functional MR. In primary MR, there is derangement of the mitral - valve itself causing left ventricular volume overload and left ventricular - dysfunction. By contrast, in secondary MR, the valve and its components are - typically normal and MR is related to changes of annular size (dilatation) and - papillary muscle displacement due to left ventricular damage caused by myocardial - infarction or dilated cardiomyopathy.In primary MR, mitral valve repair or - replacement is the first-line therapy. In secondary MR, the best management - includes standard medical therapy for heart failure and cardiac resynchronization - therapy in selected patients. Since there is no evidence from randomized studies - that surgery improves mortality, this approach may only be considered in patients - who remain symptomatic despite optimal medical therapy or in patients undergoing - coronary revascularization. -FAU - Schaefer, Arnd -AU - Schaefer A -AD - Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, - Hannover, Germany. schaefer.arnd@mh-hannover.de -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Sekundär-funktionelle Mitralinsuffizienz bei Herzinsuffizienz: Tabletten oder - Messer? -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Cardiac Pacing, Artificial/*methods -MH - Cardiotonic Agents/*therapeutic use -MH - Cardiovascular Surgical Procedures/*methods -MH - Humans -MH - Mitral Valve Insufficiency/*diagnosis/*therapy -RF - 35 -EDAT- 2009/04/17 09:00 -MHDA- 2009/07/07 09:00 -CRDT- 2009/04/17 09:00 -PHST- 2009/04/17 09:00 [entrez] -PHST- 2009/04/17 09:00 [pubmed] -PHST- 2009/07/07 09:00 [medline] -AID - 10.1007/s00059-009-3198-5 [doi] -PST - ppublish -SO - Herz. 2009 Mar;34(2):118-23. doi: 10.1007/s00059-009-3198-5. - -PMID- 22145193 -OWN - NLM -STAT- MEDLINE -DCOM- 20120103 -LR - 20121115 -IS - 1530-6550 (Print) -IS - 1530-6550 (Linking) -VI - 12 -IP - 3 -DP - 2011 -TI - A review of electrocardiography in pulmonary embolism: recognizing pulmonary - embolus masquerading as ST-elevation myocardial infarction. -PG - 157-63 -AB - A 64-year-old woman with hypertension and diabetes presented with acute shortness - of breath and left-sides chest discomfort. Electrocardiopgram (ECG) demonstrated - Q waves, coved ST-segment elevations, and T-wave inversions in leads V₁-V₄, - suggesting acute anterior ST-elevation myocardial infarction (STEMI). - catheterization revealed nonocclusive coronary artery disease with elevated - pulmonary and right heart pressures, confirmed by echocardiography. Ventilation - perfusion scan was deemed high probability for pulmonary embolism (PE). Treatment - for a submassive PE was initiated and ECG changes resolved by discharge. This - case exemplifies similarities in clinical presentation of PE and acute STEMI. The - presence of Q waves in anterior leads wih coved ST-elevation after PE has not - been described previously. We review the differential diagnosis of ST elevation - and the assorted spectrum of ECG changes seen in PE. -FAU - Raghav, Kanwal Pratap Singh -AU - Raghav KP -AD - Department of Hematology/Oncology, MD Anderson Cancer Center, Houston, TX, USA. -FAU - Makkuni, Premraj -AU - Makkuni P -FAU - Figueredo, Vincent M -AU - Figueredo VM -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - Singapore -TA - Rev Cardiovasc Med -JT - Reviews in cardiovascular medicine -JID - 100960007 -SB - IM -MH - Cardiac Catheterization -MH - Diagnosis, Differential -MH - Echocardiography, Doppler -MH - *Electrocardiography -MH - Female -MH - Humans -MH - Middle Aged -MH - Myocardial Infarction/etiology -MH - Predictive Value of Tests -MH - Pulmonary Embolism/*diagnosis/therapy -MH - Ventilation-Perfusion Ratio -EDAT- 2011/12/08 06:00 -MHDA- 2012/01/04 06:00 -CRDT- 2011/12/08 06:00 -PHST- 2011/12/08 06:00 [entrez] -PHST- 2011/12/08 06:00 [pubmed] -PHST- 2012/01/04 06:00 [medline] -PST - ppublish -SO - Rev Cardiovasc Med. 2011;12(3):157-63. - -PMID- 17332667 -OWN - NLM -STAT- MEDLINE -DCOM- 20071214 -LR - 20200106 -IS - 1734-1140 (Print) -IS - 1734-1140 (Linking) -VI - 58 Suppl -DP - 2006 -TI - Asymmetric dimethylarginine (ADMA) a novel cardiovascular risk factor--evidence - from epidemiological and prospective clinical trials. -PG - 16-20 -AB - There is a growing clinical evidence to support the hypothesis that asymmetric - dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase is a - new independent cardiovascular risk factor. ADMA mediates endothelial dysfunction - in lipid disorders, coronary artery disease, chronic heart failure, diabetes - mellitus and hypertension. The aim of this review was to summarize the latest - evidence from epidemiological and prospective clinical trials and to emphasize - the role of ADMAas a cardiovascular risk factor. -FAU - Szuba, Andrzej -AU - Szuba A -AD - Chair and Clinic of Internal and Occupational Diseases and Arterial Hypertension - in Wrocław, Pasteura 4, PL 50-367 Wrocław, Poland. szubaa@yahoo.com -FAU - Podgórski, Maciej -AU - Podgórski M -LA - eng -PT - Journal Article -PT - Review -PL - Switzerland -TA - Pharmacol Rep -JT - Pharmacological reports : PR -JID - 101234999 -RN - 0 (Biomarkers) -RN - 31C4KY9ESH (Nitric Oxide) -RN - 63CV1GEK3Y (N,N-dimethylarginine) -RN - 94ZLA3W45F (Arginine) -RN - EC 1.14.13.39 (Nitric Oxide Synthase) -SB - IM -MH - Arginine/*analogs & derivatives/blood/metabolism/pharmacology -MH - Biomarkers/blood -MH - Cardiovascular Diseases/blood/*metabolism -MH - Clinical Trials as Topic -MH - Cross-Sectional Studies -MH - Endothelium, Vascular/enzymology -MH - Humans -MH - Nitric Oxide/metabolism -MH - Nitric Oxide Synthase/antagonists & inhibitors -MH - Prospective Studies -MH - Risk Factors -RF - 39 -EDAT- 2007/03/03 09:00 -MHDA- 2007/12/15 09:00 -CRDT- 2007/03/03 09:00 -PHST- 2006/11/06 00:00 [received] -PHST- 2006/11/13 00:00 [revised] -PHST- 2007/03/03 09:00 [pubmed] -PHST- 2007/12/15 09:00 [medline] -PHST- 2007/03/03 09:00 [entrez] -PST - ppublish -SO - Pharmacol Rep. 2006;58 Suppl:16-20. - -PMID- 21188647 -OWN - NLM -STAT- MEDLINE -DCOM- 20130628 -LR - 20211020 -IS - 1559-0267 (Electronic) -IS - 1080-0549 (Linking) -VI - 44 -IP - 1 -DP - 2013 Feb -TI - Auto-antibodies as emergent prognostic markers and possible mediators of ischemic - cardiovascular diseases. -PG - 84-97 -LID - 10.1007/s12016-010-8233-z [doi] -AB - During the last 15 years, a growing body of evidence supported the fact that - auto-antibodies represent not only emergent markers but also active mediators of - cardiovascular disease (CVD), clinically represented mostly by acute coronary - syndrome (ACS) and stroke. There is a contrasted relationship between - auto-antibodies and CVD, some being protective, while others acting as potential - risk factors. Therefore, we performed a review of the literature on the - respective cardiovascular prognostic value of the most relevant auto-antibodies - in ACS and stroke, and their putative pathophysiological properties in - atherogenesis. This review highlights auto-antibodies as active modulators of the - innate immune system in atherogenesis (either toward a pro- or anti-inflammatory - response), or by affecting basal heart rate regulation (anti-apoA-1 IgG). Given - their apparent prognostic independency towards traditional cardiovascular risk - factors, the data available in the literature indicates that some of those - auto-antibodies could be of valuable help for cardiovascular risk stratification - in the future, especially because their deleterious effects have been shown to be - potentially abrogated in vivo and in vitro by existing therapeutic modalities. - Although evidence in humans is currently lacking, these studies may open - innovative therapeutic perspectives for CVD in the future. -FAU - Roux-Lombard, P -AU - Roux-Lombard P -AD - Division of Immunology and Allergy, Department of Internal Medicine, Geneva - University Hospitals, Geneva, Switzerland. -FAU - Pagano, S -AU - Pagano S -FAU - Montecucco, F -AU - Montecucco F -FAU - Satta, N -AU - Satta N -FAU - Vuilleumier, N -AU - Vuilleumier N -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Rev Allergy Immunol -JT - Clinical reviews in allergy & immunology -JID - 9504368 -RN - 0 (Autoantibodies) -RN - 0 (Biomarkers) -SB - IM -MH - Animals -MH - Autoantibodies/*immunology/metabolism -MH - Biomarkers -MH - Humans -MH - Myocardial Ischemia/*diagnosis/*immunology -MH - Prognosis -MH - Risk Factors -EDAT- 2010/12/29 06:00 -MHDA- 2013/07/03 06:00 -CRDT- 2010/12/29 06:00 -PHST- 2010/12/29 06:00 [entrez] -PHST- 2010/12/29 06:00 [pubmed] -PHST- 2013/07/03 06:00 [medline] -AID - 10.1007/s12016-010-8233-z [doi] -PST - ppublish -SO - Clin Rev Allergy Immunol. 2013 Feb;44(1):84-97. doi: 10.1007/s12016-010-8233-z. - -PMID- 19686084 -OWN - NLM -STAT- MEDLINE -DCOM- 20100506 -LR - 20100111 -IS - 1545-326X (Electronic) -IS - 0066-4219 (Linking) -VI - 61 -DP - 2010 -TI - Stress cardiomyopathy. -PG - 271-86 -LID - 10.1146/annurev.med.041908.191750 [doi] -AB - Recently, an increasing number of cases of stress cardiomyopathy, mainly - occurring in elderly women, have been documented in many parts of the world. In - Japan, this disease is known as takotsubo cardiomyopathy (named after the fishing - pot used for trapping octopus). Symptoms of this condition are akin to those of - acute myocardial infarction, but no obstructive lesions are found in the coronary - arteries, and left ventricular apical ballooning is present. Stress - cardiomyopathy is now a well-recognized cause of acute heart failure, lethal - ventricular arrhythmias, and ventricular rupture. Although the precise mechanism - of onset of this condition is still controversial, two major pathogenic - mechanisms have been proposed: catecholamine cardiotoxicity and neurogenic - stunned myocardium. We summarize the findings of studies conducted to date on - stress cardiomyopathy-from bench to bedside and bedside to bench. -FAU - Akashi, Yoshihiro J -AU - Akashi YJ -AD - Division of Cardiology, Department of Internal Medicine, St. Marianna University - School of Medicine, Kawasaki-city, Kanagawa-prefecture, Japan. - johnny@marianna-u.ac.jp -FAU - Nef, Holger M -AU - Nef HM -FAU - Möllmann, Helge -AU - Möllmann H -FAU - Ueyama, Takashi -AU - Ueyama T -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Annu Rev Med -JT - Annual review of medicine -JID - 2985151R -SB - IM -MH - Diagnostic Imaging -MH - Humans -MH - Myocardial Infarction/diagnosis/etiology/physiopathology -MH - Prognosis -MH - Risk Factors -MH - Stress, Psychological/pathology -MH - Takotsubo Cardiomyopathy/*diagnosis/*etiology/physiopathology -RF - 83 -EDAT- 2009/08/19 09:00 -MHDA- 2010/05/07 06:00 -CRDT- 2009/08/19 09:00 -PHST- 2009/08/19 09:00 [entrez] -PHST- 2009/08/19 09:00 [pubmed] -PHST- 2010/05/07 06:00 [medline] -AID - 10.1146/annurev.med.041908.191750 [doi] -PST - ppublish -SO - Annu Rev Med. 2010;61:271-86. doi: 10.1146/annurev.med.041908.191750. - -PMID- 19920161 -OWN - NLM -STAT- MEDLINE -DCOM- 20100203 -LR - 20250529 -IS - 1542-6270 (Electronic) -IS - 1060-0280 (Linking) -VI - 43 -IP - 12 -DP - 2009 Dec -TI - The impact of ezetimibe on endothelial function and other markers of - cardiovascular risk. -PG - 2021-30 -LID - 10.1345/aph.1M302 [doi] -AB - OBJECTIVE: To review the published literature characterizing the impact of - ezetimibe-containing lipid-lowering regimens on endothelial function and other - markers of cardiovascular risk and discuss the potential relevance of these - effects to the clinical benefit of ezetimibe. DATA SOURCES: A MEDLINE search - (2000-August 2009) was completed using the key words ezetimibe, statins, - endothelial function, flow-mediated dilation, pleiotropic, and inflammation to - identify relevant literature. Bibliographies of identified literature were - reviewed for additional references. STUDY SELECTION AND DATA EXTRACTION: All - clinical studies published in English that evaluated the effect of ezetimibe on - ancillary endpoints of cardiovascular disease risk, including endothelial - function, inflammation, thrombosis, and oxidative stress, were evaluated. DATA - SYNTHESIS: Recent studies in patients with coronary artery disease (CAD), heart - failure, and hypercholesterolemia have demonstrated that treatment with ezetimibe - for 4-12 weeks elicits no improvement of endothelial function or other measures - of cardiovascular disease risk. In contrast, other studies have reported that - ezetimibe improves endothelial function in certain patient populations, including - those with rheumatoid arthritis, CAD with type 2 diabetes, and metabolic - syndrome. However, the statin monotherapy comparator groups in these studies that - yielded equivalent reductions in cholesterol were superior, or at least - equivalent to, ezetimibe-containing regimens in the improvement of these - ancillary endpoints. CONCLUSIONS: Overall, the evidence to date suggests that - administration of ezetimibe, either as monotherapy or in combination with a - statin, exerts minimal beneficial effects on endothelial function and other - ancillary measures of cardiovascular disease risk beyond those conferred by its - cholesterol-lowering effects. Studies with larger sample sizes and follow-up - beyond 12 weeks remain necessary to further define the impact of ezetimibe on the - processes integral to the pathogenesis and progression of cardiovascular disease. -FAU - Bass, Almasa -AU - Bass A -AD - Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of - Pharmacy, University of North Carolina at Chapel Hill, 27599, USA. -FAU - Hinderliter, Alan L -AU - Hinderliter AL -FAU - Lee, Craig R -AU - Lee CR -LA - eng -GR - 0765247U/AHA/American Heart Association-American Stroke Association/United States -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20091117 -PL - United States -TA - Ann Pharmacother -JT - The Annals of pharmacotherapy -JID - 9203131 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Azetidines) -RN - EOR26LQQ24 (Ezetimibe) -SB - IM -MH - Animals -MH - Anticholesteremic Agents/*pharmacology -MH - Azetidines/*pharmacology -MH - Cardiovascular Diseases/etiology/*prevention & control -MH - Clinical Trials as Topic -MH - Endothelium, Vascular/drug effects/metabolism -MH - Ezetimibe -MH - Humans -MH - Hypercholesterolemia/drug therapy -MH - Risk Factors -RF - 41 -EDAT- 2009/11/19 06:00 -MHDA- 2010/02/04 06:00 -CRDT- 2009/11/19 06:00 -PHST- 2009/11/19 06:00 [entrez] -PHST- 2009/11/19 06:00 [pubmed] -PHST- 2010/02/04 06:00 [medline] -AID - aph.1M302 [pii] -AID - 10.1345/aph.1M302 [doi] -PST - ppublish -SO - Ann Pharmacother. 2009 Dec;43(12):2021-30. doi: 10.1345/aph.1M302. Epub 2009 Nov - 17. - -PMID- 19825494 -OWN - NLM -STAT- MEDLINE -DCOM- 20091230 -LR - 20171116 -IS - 1932-2275 (Print) -IS - 1932-2275 (Linking) -VI - 27 -IP - 3 -DP - 2009 Sep -TI - Perioperative use of beta-blockers in the elderly patient. -PG - 581-97, table of contents -LID - 10.1016/j.anclin.2009.07.015 [doi] -AB - Elderly patients are increasingly referred for complex surgery, but are at - particular risk for coronary artery disease. One strategy to prevent - perioperative cardiac events in elderly patients is to employ perioperative - beta-blockade, but doing so has the potential to increase the incidence of - congestive heart failure, perioperative hypotension, bradycardia, and stroke. - This article examines common comorbidities in the elderly who may benefit from - the chronic use of beta-blockers, prophylactic perioperative use of beta-blockers - including timing, dosage, and choice of beta-blocker, the pharmacologic effects - of aging, and recommendations on the use of beta-blockers. -FAU - Lombaard, Stefan A -AU - Lombaard SA -AD - Department of Anesthesiology and Pain Medicine, University of Washington Medical - Center, Seattle, WA 98195-6540, USA. lombaard@u.washington.edu -FAU - Robbertze, Reinette -AU - Robbertze R -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - Anesthesiol Clin -JT - Anesthesiology clinics -JID - 101273663 -RN - 0 (Adrenergic beta-Antagonists) -SB - IM -MH - Adrenergic beta-Antagonists/administration & dosage/*therapeutic use -MH - Aged/*physiology -MH - Aged, 80 and over -MH - Carcinoma, Renal Cell/surgery -MH - Cardiovascular Diseases/drug therapy -MH - Contraindications -MH - Humans -MH - Intraoperative Complications/*prevention & control -MH - Kidney Neoplasms/surgery -MH - Male -MH - Nephrectomy -MH - *Perioperative Care -RF - 84 -EDAT- 2009/10/15 06:00 -MHDA- 2009/12/31 06:00 -CRDT- 2009/10/15 06:00 -PHST- 2009/10/15 06:00 [entrez] -PHST- 2009/10/15 06:00 [pubmed] -PHST- 2009/12/31 06:00 [medline] -AID - S1932-2275(09)00057-3 [pii] -AID - 10.1016/j.anclin.2009.07.015 [doi] -PST - ppublish -SO - Anesthesiol Clin. 2009 Sep;27(3):581-97, table of contents. doi: - 10.1016/j.anclin.2009.07.015. - -PMID- 19943320 -OWN - NLM -STAT- MEDLINE -DCOM- 20100224 -LR - 20250529 -IS - 1520-7560 (Electronic) -IS - 1520-7552 (Print) -IS - 1520-7552 (Linking) -VI - 26 -IP - 1 -DP - 2010 Jan -TI - Diabetes and microvascular pathophysiology: role of epidermal growth factor - receptor tyrosine kinase. -PG - 13-6 -LID - 10.1002/dmrr.1050 [doi] -AB - Type 2 diabetes is responsible for the increased prevalence of ischaemic heart - disease, generally related to coronary artery disease, which is associated with - increased morbidity and death in diabetic patients. Epidermal growth factor - receptor (EGFR) tyrosine kinase, one of the many factors involved in cell growth - and migration, has been shown to be key element in the development of microvessel - myogenic tone. In a recent study, we have shown that microvascular dysfunction in - type 2 diabetes is dependent on the exacerbation of the EGFR tyrosine kinase - phosphorylation. Thus, further elucidation of this EGFR transactivation and down - stream signalling will offer a new direction to investigate the mechanism of - microvascular dysfunction responsible for heart disease that occurs in type 2 - diabetes. In this review, we discuss the link between the EGFR transactivation - and microvascular dysfunction that occurs in type 2 diabetes. -CI - Copyright (c) 2009 John Wiley & Sons, Ltd. -FAU - Matrougui, Khalid -AU - Matrougui K -AD - Department of Physiology, and Hypertension and Renal Center of Excellence, Tulane - University, 1430 Tulane Ave., New Orleans, LA 70112, USA. kmatroug@tulane.edu -LA - eng -GR - P20 RR017659/RR/NCRR NIH HHS/United States -GR - P20 RR 017659/RR/NCRR NIH HHS/United States -GR - HL26371/HL/NHLBI NIH HHS/United States -GR - R01 HL026371/HL/NHLBI NIH HHS/United States -GR - R01 HL095566/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - England -TA - Diabetes Metab Res Rev -JT - Diabetes/metabolism research and reviews -JID - 100883450 -RN - EC 2.7.10.1 (ErbB Receptors) -RN - EC 3.4.24.24 (Matrix Metalloproteinase 2) -RN - EC 3.4.24.35 (Matrix Metalloproteinase 9) -SB - IM -MH - Animals -MH - Diabetes Mellitus, Type 2/enzymology/genetics/pathology/*physiopathology -MH - Diabetic Angiopathies/enzymology/genetics/*physiopathology -MH - Disease Models, Animal -MH - ErbB Receptors/genetics/*physiology -MH - Humans -MH - Matrix Metalloproteinase 2/metabolism -MH - Matrix Metalloproteinase 9/metabolism -MH - Microcirculation/*physiology -PMC - PMC2823570 -MID - NIHMS162679 -EDAT- 2009/11/28 06:00 -MHDA- 2010/02/25 06:00 -PMCR- 2011/01/01 -CRDT- 2009/11/28 06:00 -PHST- 2009/11/28 06:00 [entrez] -PHST- 2009/11/28 06:00 [pubmed] -PHST- 2010/02/25 06:00 [medline] -PHST- 2011/01/01 00:00 [pmc-release] -AID - 10.1002/dmrr.1050 [doi] -PST - ppublish -SO - Diabetes Metab Res Rev. 2010 Jan;26(1):13-6. doi: 10.1002/dmrr.1050. - -PMID- 23256710 -OWN - NLM -STAT- MEDLINE -DCOM- 20130725 -LR - 20131106 -IS - 1744-7682 (Electronic) -IS - 1471-2598 (Linking) -VI - 13 -IP - 3 -DP - 2013 Mar -TI - Cell-based vasculogenic studies in preclinical models of chronic myocardial - ischaemia and hibernation. -PG - 411-28 -LID - 10.1517/14712598.2013.748739 [doi] -AB - INTRODUCTION: Coronary artery disease commonly leads to myocardial ischaemia and - hibernation. Relevant preclinical models of these conditions are essential to - evaluate new therapeutic options such as cell-based vasculogenic therapies. AREAS - COVERED: In this article, the authors first review basic concepts of myocardial - ischaemia/hibernation and relevant techniques to assess myocardial viability. - Then, preclinical models of chronic myocardial ischaemia and hibernation, induced - by devices such as ameroid constrictors, Delrin stenosis, hydraulic occluders, - and coils/stents are described. Lastly, the authors discuss cell-based - vasculogenic therapy, and summarise studies conducted in large animal models of - chronic myocardial ischaemia and hibernation. EXPERT OPINION: Approximately - one-third of patients with viable myocardium do not undergo revascularisation; - however, this population is at high risk for cardiac events and would surely - benefit from effective cell-based therapy. Because of the modest benefits in - clinical studies, preclinical models accurately representing clinical myocardial - ischemia/hibernation are necessary to better understand and appropriately direct - regenerative therapy research. -FAU - Giordano, Céline -AU - Giordano C -AD - University of Ottawa Heart Institute, Division of Cardiac Surgery, 40 Ruskin - Street, Suite 3403, Ottawa, Ontario, K1Y 4W7, Canada. -FAU - Kuraitis, Drew -AU - Kuraitis D -FAU - Beanlands, Rob S B -AU - Beanlands RS -FAU - Suuronen, Erik J -AU - Suuronen EJ -FAU - Ruel, Marc -AU - Ruel M -LA - eng -GR - MOP-77536/Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121221 -PL - England -TA - Expert Opin Biol Ther -JT - Expert opinion on biological therapy -JID - 101125414 -SB - IM -MH - Animals -MH - Chronic Disease -MH - *Disease Models, Animal -MH - Humans -MH - Myocardial Ischemia/*pathology -MH - Myocardial Stunning/*pathology -MH - Neovascularization, Pathologic/*pathology -EDAT- 2012/12/22 06:00 -MHDA- 2013/07/26 06:00 -CRDT- 2012/12/22 06:00 -PHST- 2012/12/22 06:00 [entrez] -PHST- 2012/12/22 06:00 [pubmed] -PHST- 2013/07/26 06:00 [medline] -AID - 10.1517/14712598.2013.748739 [doi] -PST - ppublish -SO - Expert Opin Biol Ther. 2013 Mar;13(3):411-28. doi: 10.1517/14712598.2013.748739. - Epub 2012 Dec 21. - -PMID- 17380165 -OWN - NLM -STAT- MEDLINE -DCOM- 20070412 -LR - 20071115 -IS - 1743-4300 (Electronic) -IS - 1743-4297 (Linking) -VI - 4 -IP - 4 -DP - 2007 Apr -TI - Drug insight: statins for nonischemic heart failure--evidence and potential - mechanisms. -PG - 196-205 -AB - While 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, also known as - statins, have a well-established in role in the treatment and prevention of - ischemic coronary artery disease, their utility in the setting of heart failure - (HF) and left ventricular (LV) dysfunction remains under investigation. Although - a reduction in LDL is the major effect of statin therapy, pleiotropic effects - have been demonstrated, which could be responsible for the reduction in morbidity - and mortality seen with statin use in patients with HF. Patients with both - ischemic and nonischemic HF have been shown to have improved survival with statin - therapy, and patients receiving statin therapy are less likely to develop HF. - Studies have demonstrated that statins reduce inflammation, improve endothelial - function, decrease thrombogenicity, and improve LV and autonomic function. In - this Review, we present the literature supporting the pleiotropic effects of - statin therapy in patients with HF or LV dysfunction, and discuss the mechanisms - by which statins might elicit the improvements in morbidity and mortality seen in - these patients. -FAU - Lipinski, Michael J -AU - Lipinski MJ -AD - University of Virginia Health System, Department of Internal Medicine, - Charlottesville, VA 22908, USA. lips_94306@yahoo.com -FAU - Abbate, Antonio -AU - Abbate A -FAU - Fuster, Valentin -AU - Fuster V -FAU - Vetrovec, George W -AU - Vetrovec GW -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PL - England -TA - Nat Clin Pract Cardiovasc Med -JT - Nature clinical practice. Cardiovascular medicine -JID - 101226507 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Dose-Response Relationship, Drug -MH - Drug Administration Schedule -MH - Female -MH - Heart Failure/diagnosis/*drug therapy/mortality -MH - Heart Function Tests -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Male -MH - Middle Aged -MH - Prognosis -MH - Retrospective Studies -MH - Risk Assessment -MH - Survival Analysis -MH - Treatment Outcome -MH - Ventricular Dysfunction, Left/diagnosis/*drug therapy/mortality -MH - Ventricular Remodeling/drug effects -RF - 83 -EDAT- 2007/03/24 09:00 -MHDA- 2007/04/14 09:00 -CRDT- 2007/03/24 09:00 -PHST- 2006/09/01 00:00 [received] -PHST- 2007/01/17 00:00 [accepted] -PHST- 2007/03/24 09:00 [pubmed] -PHST- 2007/04/14 09:00 [medline] -PHST- 2007/03/24 09:00 [entrez] -AID - ncpcardio0855 [pii] -AID - 10.1038/ncpcardio0855 [doi] -PST - ppublish -SO - Nat Clin Pract Cardiovasc Med. 2007 Apr;4(4):196-205. doi: 10.1038/ncpcardio0855. - -PMID- 20055689 -OWN - NLM -STAT- MEDLINE -DCOM- 20100602 -LR - 20101118 -IS - 1744-7623 (Electronic) -IS - 1472-8214 (Linking) -VI - 15 -IP - 1 -DP - 2010 Mar -TI - Emerging drugs for acute myocardial infarction. -PG - 87-105 -LID - 10.1517/14728210903405619 [doi] -AB - IMPORTANCE OF THE FIELD: The present review is aimed at going over the - pharmacological profile (and the clinical impact) of the emerging drugs involved - in the management of patients with ST-elevation myocardial infarction (STEMI) in - order to provide the cardiologists who deal with these patients in the early - phase with the most recent evidence on this topic. AREAS COVERED IN THIS REVIEW: - Anticoagulant and antiplatelet drugs are the main cornerstones of therapy in the - treatment of STEMI patients undergoing primary percutaneous coronary intervention - (PCI). The main issues that clinicians have to deal with are represented by - balancing thrombotic and bleeding risks. In tailoring therapy, variables such as - age, sex and previous disease should be taken into account, as well as ongoing - complications (such as acute renal failure) that could affect hemostasis. Despite - the well-established clinical benefits of antiplatelet agents, questions remain, - mainly surrounding potential for variable platelet response, which are strictly - related to non-genetic (i.e., diet, drug-drug interaction, clinical factors such - as obesity, diabetes mellitus, and inflammation) and genetic determinants. WHAT - THE READER WILL GAIN: In their daily practice, cardiologists cannot abstract from - the knowledge and updating on the ongoing research fields as well as the newly - developed drugs, which they should frame in the very patient in the attempt to - the develop a personalized medical strategy. These include also the - pharmacological option(s) in the treatment of the reperfusion injury, the - metabolic aspects and the stem cell therapy. TAKE HOME MASSAGE: In our opinion, - the goal of ongoing research on the pharmacological approach to STEMI patients is - a personalized medical strategy that relies on critical clinicians who merge - newly developed acquisitions on this topic and a more complete, systemic and - critical approach to the patient. -FAU - Lazzeri, Chiara -AU - Lazzeri C -AD - University of Florence, Department of Heart and Vessels, Florence, Italy. -FAU - Tarquini, Roberto -AU - Tarquini R -FAU - Valente, Serafina -AU - Valente S -FAU - Abbate, Rosanna -AU - Abbate R -FAU - Gensini, G F -AU - Gensini GF -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Opin Emerg Drugs -JT - Expert opinion on emerging drugs -JID - 101135662 -RN - 0 (Drugs, Investigational) -RN - 0 (Hematologic Agents) -RN - 0 (Vasodilator Agents) -SB - IM -MH - Angioplasty, Balloon, Coronary/methods -MH - Animals -MH - Defibrillators, Implantable -MH - Drug Delivery Systems/methods -MH - Drugs, Investigational/*therapeutic use -MH - Hematologic Agents/*therapeutic use -MH - Humans -MH - Intra-Aortic Balloon Pumping -MH - Myocardial Infarction/*drug therapy/therapy -MH - No-Reflow Phenomenon/prevention & control -MH - Reperfusion Injury/*drug therapy -MH - Shock, Cardiogenic/*drug therapy/therapy -MH - Stem Cell Transplantation/statistics & numerical data -MH - Vasodilator Agents/*therapeutic use -RF - 153 -EDAT- 2010/01/09 06:00 -MHDA- 2010/06/03 06:00 -CRDT- 2010/01/09 06:00 -PHST- 2010/01/09 06:00 [entrez] -PHST- 2010/01/09 06:00 [pubmed] -PHST- 2010/06/03 06:00 [medline] -AID - 10.1517/14728210903405619 [doi] -PST - ppublish -SO - Expert Opin Emerg Drugs. 2010 Mar;15(1):87-105. doi: 10.1517/14728210903405619. - -PMID- 19159122 -OWN - NLM -STAT- MEDLINE -DCOM- 20090413 -LR - 20191111 -IS - 1175-3277 (Print) -IS - 1175-3277 (Linking) -VI - 8 -IP - 6 -DP - 2008 -TI - Peripheral arterial disease in the elderly: recognition and management. -PG - 353-64 -LID - 10.2165/0129784-200808060-00002 [doi] -AB - Peripheral arterial disease (PAD) is a common but frequently overlooked vascular - disease, often affecting the lower extremities. The prevalence of PAD increases - exponentially with age, and this is of particular concern among the elderly - population because this condition frequently signals disease in other vascular - beds, including the coronary arteries and/or cerebral vasculature. In addition to - the increased risk of cardiovascular disease and stroke, patients with PAD may - also experience functional impairment and decreased quality of life. The - ankle-brachial index is the most effective and widely used screening tool for - detecting PAD and should be performed when PAD is suspected, based on the medical - history or physical examination. Current treatment guidelines recommend risk - factor modification, including exercise therapy and smoking cessation - interventions, combined with pharmacologic measures for secondary prevention and - management of symptoms of PAD. Antiplatelet therapy is an integral component of - global cardiovascular risk reduction strategies in patients with PAD.Current - guidelines provide a significant opportunity for practitioners to detect and - treat patients with PAD in a timely and effective manner, thereby improving the - overall mortality, morbidity, and quality of life associated with this disease. -FAU - Aronow, Herbert -AU - Aronow H -AD - Clinical Scholars Program, Michigan Heart & Vascular Institute, St Joseph Mercy - Hospital, Ann Arbor, Michigan, USA. haronow@michiganheart.com -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Aged -MH - Ankle Brachial Index -MH - *Exercise Therapy -MH - Humans -MH - *Peripheral Vascular Diseases/diagnosis/therapy -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Practice Guidelines as Topic -MH - Risk Factors -MH - *Smoking Cessation -RF - 93 -EDAT- 2009/01/23 09:00 -MHDA- 2009/04/14 09:00 -CRDT- 2009/01/23 09:00 -PHST- 2009/01/23 09:00 [entrez] -PHST- 2009/01/23 09:00 [pubmed] -PHST- 2009/04/14 09:00 [medline] -AID - 862 [pii] -AID - 10.2165/0129784-200808060-00002 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2008;8(6):353-64. doi: 10.2165/0129784-200808060-00002. - -PMID- 17618829 -OWN - NLM -STAT- MEDLINE -DCOM- 20080124 -LR - 20220419 -IS - 1443-9506 (Print) -IS - 1443-9506 (Linking) -VI - 16 Suppl 3 -DP - 2007 -TI - Biomarkers of cardiovascular damage and dysfunction--an overview. -PG - S71-82 -AB - Acute coronary syndromes (ACS) are due to the rupture or erosion of atheromatous - plaques. This produces, depending on plaque size, vascular anatomy and degree of - collateral circulation, progressive tissue ischaemia which may progress to - cardiomyocyte necrosis and subsequent cardiac remodelling. Cardiac biomarkers can - be used for diagnosis and assessment of all of these stages. Markers to detect - myocardial ischaemia at the pre-infarction stage are potentially the most - interesting but also the most challenging. An ischaemia marker offers the - opportunity to intervene to prevent progression to infarction. The challenges - with potential ischaemia markers are specificity and the diagnostic reference - standard for assessment. To date, only one, ischaemia modified albumin, has - reached the point where clinical studies can be performed. The measurement of the - cardiac troponins, cardiac troponin T and cardiac troponin I, has become the - diagnostic standard as the biomarker of myocardial necrosis. The sensitive nature - of troponin measurement has also revealed that myocardial necrosis is also found - in a range of other clinical situations. This illustrates the need to use all - clinical information for diagnosis of acute myocardial infarction. The - measurement of B type natriuretic peptides can be shown to be diagnostic and - prognostic for both acute ACS and detecting the sequelae of post infarction - myocardial insufficiency. The role of the B type natriuretic peptides in - detection of cardiac failure, acute and chronic, is well defined. Their role in - ACS remains the subject of further studies. -FAU - Collinson, Paul O -AU - Collinson PO -AD - Departments of Chemical Pathology, Cardiac Research and Cardiology, St George's - Hospital and Medical School, Blackshaw Road, London SW17 0QT, United Kingdom. - paul.collinson@stgeorges.nhs.uk -FAU - Gaze, David C -AU - Gaze DC -LA - eng -PT - Journal Article -PT - Review -DEP - 20070706 -PL - Australia -TA - Heart Lung Circ -JT - Heart, lung & circulation -JID - 100963739 -RN - 0 (Biomarkers) -RN - 0 (Peptide Fragments) -RN - 0 (Troponin I) -RN - 0 (Troponin T) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Acute Coronary Syndrome -MH - Acute Disease -MH - *Biomarkers -MH - Cardiovascular Diseases/*diagnosis/physiopathology -MH - Chest Pain -MH - Humans -MH - Myocardial Infarction -MH - Myocardial Ischemia -MH - Natriuretic Peptide, Brain -MH - Peptide Fragments -MH - Prognosis -MH - Risk Assessment -MH - Troponin I -MH - Troponin T -RF - 13 -EDAT- 2007/07/10 09:00 -MHDA- 2008/01/25 09:00 -CRDT- 2007/07/10 09:00 -PHST- 2007/07/10 09:00 [pubmed] -PHST- 2008/01/25 09:00 [medline] -PHST- 2007/07/10 09:00 [entrez] -AID - S1443-9506(07)00222-3 [pii] -AID - 10.1016/j.hlc.2007.05.006 [doi] -PST - ppublish -SO - Heart Lung Circ. 2007;16 Suppl 3:S71-82. doi: 10.1016/j.hlc.2007.05.006. Epub - 2007 Jul 6. - -PMID- 24267442 -OWN - NLM -STAT- MEDLINE -DCOM- 20140123 -LR - 20131125 -IS - 1873-1740 (Electronic) -IS - 0033-0620 (Linking) -VI - 56 -IP - 3 -DP - 2013 Nov-Dec -TI - Health promotion and cardiovascular disease prevention in sub-Saharan Africa. -PG - 344-55 -LID - S0033-0620(13)00180-1 [pii] -LID - 10.1016/j.pcad.2013.10.007 [doi] -AB - Recent population studies demonstrate an increasing burden of cardiovascular - disease (CVD) and related risk factors in sub-Saharan Africa (SSA). The - mitigation or reversal of this trend calls for effective health promotion and - preventive interventions. In this article, we review the core principles, - challenges, and progress in promoting cardiovascular health with special emphasis - on interventions to address physical inactivity, poor diet, tobacco use, and - adverse cardiometabolic risk factor trends in SSA. We focus on the five essential - strategies of the Ottawa Charter for Health Promotion. Successes highlighted - include community-based interventions in Ghana, Nigeria, South Africa, and - Mauritius and school-based programs in Kenya, Namibia, and Swaziland. We address - the major challenge of developing integrated interventions, and showcase - partnerships opportunities. We conclude by calling for intersectoral partnerships - for effective and sustainable intervention strategies to advance cardiovascular - health promotion and close the implementation gap in accordance with the 2009 - Nairobi Call to Action on Health Promotion. -CI - © 2013. -FAU - Sampson, Uchechukwu K A -AU - Sampson UK -AD - Department of Medicine, Vanderbilt University Medical Center, Nashville, TN; - Department of Pathology, Microbiology and Immunology, VUMC, Nashville, TN; - Department of Radiology and Radiological Sciences, VUMC, Nashville, TN. - Electronic address: u.sampson@vanderbilt.edu. -FAU - Amuyunzu-Nyamongo, Mary -AU - Amuyunzu-Nyamongo M -FAU - Mensah, George A -AU - Mensah GA -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131009 -PL - United States -TA - Prog Cardiovasc Dis -JT - Progress in cardiovascular diseases -JID - 0376442 -SB - IM -MH - Africa South of the Sahara/epidemiology -MH - Cardiovascular Diseases/epidemiology/*prevention & control -MH - Delivery of Health Care/*organization & administration -MH - *Developing Countries -MH - *Health Promotion -MH - Humans -MH - Risk Factors -OTO - NOTNLM -OT - AMREF -OT - ARL -OT - African Medical and Research Foundation -OT - African Research Leader -OT - CDTI -OT - CORIS -OT - CVD -OT - Cardiovascular disease -OT - Coronary Risk Factor Study -OT - DALY -OT - DFID -OT - Department for International Development -OT - GDP -OT - HPSI -OT - Health Promoting Schools Initiative -OT - Health promotion -OT - HiAP -OT - LMIC -OT - MRC -OT - Medical Research Council -OT - NCD -OT - NHLBI -OT - National Heart Lung and Blood Institute -OT - Non-communicable diseases -OT - PHC -OT - Prevention -OT - SSA -OT - Sub-Saharan Africa -OT - UIS -OT - UNESCO -OT - UNESCO Institute for Statistics -OT - UNFPA -OT - UNICEF -OT - United Nations Children's Fund -OT - United Nations Educational, Scientific and Cultural Organization -OT - United Nations Population Fund -OT - WHO -OT - WHO-AFRO -OT - World Health Organization -OT - World Health Organization Regional Office for Africa -OT - community directed treatment with ivermectin -OT - disability adjusted life years -OT - gross domestic product -OT - health in all policies -OT - low-to-middle income countries -OT - non-communicable disease -OT - primary health care -OT - sub-Saharan Africa -EDAT- 2013/11/26 06:00 -MHDA- 2014/01/24 06:00 -CRDT- 2013/11/26 06:00 -PHST- 2013/11/26 06:00 [entrez] -PHST- 2013/11/26 06:00 [pubmed] -PHST- 2014/01/24 06:00 [medline] -AID - S0033-0620(13)00180-1 [pii] -AID - 10.1016/j.pcad.2013.10.007 [doi] -PST - ppublish -SO - Prog Cardiovasc Dis. 2013 Nov-Dec;56(3):344-55. doi: 10.1016/j.pcad.2013.10.007. - Epub 2013 Oct 9. - -PMID- 20863278 -OWN - NLM -STAT- MEDLINE -DCOM- 20110330 -LR - 20190911 -IS - 1873-5592 (Electronic) -IS - 1389-4501 (Linking) -VI - 12 -IP - 1 -DP - 2011 Jan -TI - Atherosclerosis, degenerative aortic stenosis and statins. -PG - 115-21 -AB - Aortic stenosis is the most common valvular heart disease among adult subjects in - western countries The current treatment for aortic stenosis is aortic valve - replacement. The possibility of a medical treatment that can slow the progression - of aortic stenosis is very fascinating and statins have been tested to reduce the - progression of degenerative aortic stenosis (DAS). The rationale for statin - treatment in DAS has a deep pathophysiological substrate, in fact inflammation - and lipid infiltration constitute the same histopathological pattern of both - aortic stenosis and atherosclerosis and these two conditions have the same risk - factors. Whether retrospective studies have shown some efficacy of statins in - halting the progression of DAS, prospective trials have shown controversial - results. A recently published large and randomized controlled trial SEAS found - that statins have no significant effect on the progression of aortic stenosis, - the ASTRONOMER, recently confirmed this data. The most plausible hypothesis is - that coronary artery disease and DAS, have a common pathogenetic background and a - distinct evolution due to different factors (mechanical stress, genetic factors, - interaction between inflammatory cells and calcification mediators). Thus, - treatment with statins is not recommended in patients with valvular aortic - stenosis and without conventional indications to lipid-lowering treatment. -FAU - Novo, Giuseppina -AU - Novo G -AD - Division of Cardiovascular Diseases, University of Palermo, Italy. - novosav@unipa.it -FAU - Fazio, Giovanni -AU - Fazio G -FAU - Visconti, Claudia -AU - Visconti C -FAU - Carità, Patrizia -AU - Carità P -FAU - Maira, Ermanno -AU - Maira E -FAU - Fattouch, Khalil -AU - Fattouch K -FAU - Novo, Salvatore -AU - Novo S -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Drug Targets -JT - Current drug targets -JID - 100960531 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Animals -MH - Aortic Valve Stenosis/*drug therapy/*etiology/physiopathology -MH - Atherosclerosis/drug therapy/*etiology/physiopathology -MH - Evidence-Based Medicine -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology/*therapeutic use -EDAT- 2010/09/25 06:00 -MHDA- 2011/03/31 06:00 -CRDT- 2010/09/25 06:00 -PHST- 2009/11/27 00:00 [received] -PHST- 2010/03/16 00:00 [accepted] -PHST- 2010/09/25 06:00 [entrez] -PHST- 2010/09/25 06:00 [pubmed] -PHST- 2011/03/31 06:00 [medline] -AID - BSP/CDT/E-Pub/00167 [pii] -AID - 10.2174/138945011793591545 [doi] -PST - ppublish -SO - Curr Drug Targets. 2011 Jan;12(1):115-21. doi: 10.2174/138945011793591545. - -PMID- 17575808 -OWN - NLM -STAT- MEDLINE -DCOM- 20070711 -LR - 20071115 -IS - 0340-9937 (Print) -IS - 0340-9937 (Linking) -VI - 31 Suppl 3 -DP - 2006 Dec -TI - Effects of omega-3 polyunsaturated fatty acids on depression. -PG - 69-74 -AB - Depression is characterised by depressed mood or/ and the loss of interest or - pleasure in nearly all activities for a substantial period of time, causing - significant distress. Depression is a potentially life-threatening disease. It is - a major risk factor for suicide as well as coronary artery disease (CAD) and - sudden cardiac death (SCD). It also may be associated with impaired endothelial - dysfunction and decreased heart rate variability (HRV). Both conditions seem to - persist in patients with depression despite successful antidepressant treatment. - During the last few years epidemiological studies as well as clinical trials have - suggested a significant role of omega-3 fatty acids in the pathogenesis of - depression. As omega-3 fatty acids have been demonstrated to also beneficially - influence many of the conditions depression is a risk factor for (CAD, SCD) or - may be associated with (decreased HRV, endothelial dysfunction), they may well - represent a major advance in the treatment of depression. However more large - randomized clinical trials are clearly needed to substantiate that claim. -FAU - Severus, W Emanuel -AU - Severus WE -AD - Ludwig-Maximilians-University, Department of Psychiatry, Munich, Germany. -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -RN - 0 (Dietary Fats) -RN - 0 (Fatty Acids, Omega-3) -SB - IM -MH - Clinical Trials as Topic/statistics & numerical data -MH - Depression/*diet therapy/*epidemiology -MH - Dietary Fats/*therapeutic use -MH - Fatty Acids, Omega-3/*therapeutic use -MH - Humans -MH - Prevalence -MH - Risk Assessment/*methods -MH - Risk Factors -MH - Treatment Outcome -RF - 45 -EDAT- 2007/06/20 09:00 -MHDA- 2007/07/12 09:00 -CRDT- 2007/06/20 09:00 -PHST- 2007/06/20 09:00 [pubmed] -PHST- 2007/07/12 09:00 [medline] -PHST- 2007/06/20 09:00 [entrez] -PST - ppublish -SO - Herz. 2006 Dec;31 Suppl 3:69-74. - -PMID- 16782554 -OWN - NLM -STAT- MEDLINE -DCOM- 20060912 -LR - 20220408 -IS - 1568-9972 (Print) -IS - 1568-9972 (Linking) -VI - 5 -IP - 5 -DP - 2006 May -TI - Connective tissue diseases and cardiac rhythm disorders: an overview. -PG - 306-13 -AB - Cardiovascular involvement is common in connective tissue diseases (CTD), with - relevant implications in terms of morbidity and mortality. Rhythm disturbances, - i.e. conduction defects and tachyarrhythmias, represent a frequent clinical - manifestation of CTD-associated cardiovascular damage and a possible cause of - sudden death. The underlying arrhythmogenic mechanisms are probably multiple and - intriguing, even though the myocardial fibrosis frequently observed at the - pathological examination seems to play a pivotal role. Myocardial fibrosis is - produced directly by inflammatory processes, or indirectly as a consequence of - coronary artery occlusive disease, and it may affect the conduction system also - representing the pathological substrate for reentry circles. An overview of - CTD-associated cardiac rhythm disturbances is here provided. Among CTD-associated - rhythm disorders, congenital heart block (CHB), which represents the main feature - of neonatal lupus, a rare syndrome related to the transplacental passage of - autoantibodies from anti-Ro/SSA-positive mother to their newborns, seems to - acknowledge a peculiar mechanism of disease possibly dependent on a direct - arrhythmogenicity of anti-Ro/SSA antibodies. Moreover, new anti-Ro/SSA-associated - EKG abnormalities have been recently described in children (sinus bradycardia and - corrected QT (QTc) interval prolongation) as well as in adults (QTc interval - prolongation). -FAU - Lazzerini, Pietro Enea -AU - Lazzerini PE -AD - Department of Clinical Medicine and Immunological Sciences, Division of Clinical - Immunology, University of Siena, Viale Bracci, 53100 Siena, Italy. - pietroenea@yahoo.it -FAU - Capecchi, Pier Leopoldo -AU - Capecchi PL -FAU - Guideri, Francesca -AU - Guideri F -FAU - Acampa, Maurizio -AU - Acampa M -FAU - Galeazzi, Mauro -AU - Galeazzi M -FAU - Laghi Pasini, Franco -AU - Laghi Pasini F -LA - eng -PT - Journal Article -PT - Review -DEP - 20051209 -PL - Netherlands -TA - Autoimmun Rev -JT - Autoimmunity reviews -JID - 101128967 -RN - 0 (Antibodies, Antinuclear) -RN - 0 (SS-A antibodies) -SB - IM -MH - Antibodies, Antinuclear/immunology -MH - Arrhythmias, Cardiac/*etiology/immunology -MH - Connective Tissue Diseases/*complications/immunology -MH - Humans -RF - 40 -EDAT- 2006/06/20 09:00 -MHDA- 2006/09/13 09:00 -CRDT- 2006/06/20 09:00 -PHST- 2005/09/26 00:00 [received] -PHST- 2005/11/03 00:00 [accepted] -PHST- 2006/06/20 09:00 [pubmed] -PHST- 2006/09/13 09:00 [medline] -PHST- 2006/06/20 09:00 [entrez] -AID - S1568-9972(05)00211-9 [pii] -AID - 10.1016/j.autrev.2005.11.002 [doi] -PST - ppublish -SO - Autoimmun Rev. 2006 May;5(5):306-13. doi: 10.1016/j.autrev.2005.11.002. Epub 2005 - Dec 9. - -PMID- 18322158 -OWN - NLM -STAT- MEDLINE -DCOM- 20081007 -LR - 20151119 -IS - 1533-3450 (Electronic) -IS - 1046-6673 (Linking) -VI - 19 -IP - 9 -DP - 2008 Sep -TI - Use of cardiac biomarkers in end-stage renal disease. -PG - 1643-52 -LID - 10.1681/ASN.2008010012 [doi] -AB - Mortality among patients with ESRD remains high because of an excessive - cardiovascular risk related to a very high incidence of cardiac hypertrophy, - cardiomyopathy, heart failure, and coronary artery disease. Identifying serum - biomarkers that are useful in profiling cardiovascular risk and enabling - stratification of early mortality and cardiovascular risk is an important goal in - the treatment of these patients. This review examines current evidence pertaining - to the role and utility of two emerging cardiac biomarkers, B-type natriuretic - peptide and cardiac troponin T, in patients with ESRD. Together, these data - demonstrate how these two cardiac biomarkers may play an adjunctive role to - echocardiography in assessing cardiovascular risk and how they may aid in the - clinical treatment of these patients. -FAU - Wang, Angela Yee-Moon -AU - Wang AY -AD - University Department of Medicine, Queen Mary Hospital, University of Hong Kong, - 102 Pok Fu Lam Road, Hong Kong. aymwang@hku.hk -FAU - Lai, Kar-Neng -AU - Lai KN -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080305 -PL - United States -TA - J Am Soc Nephrol -JT - Journal of the American Society of Nephrology : JASN -JID - 9013836 -RN - 0 (Biomarkers) -RN - 0 (Peptide Fragments) -RN - 0 (Troponin T) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Biomarkers/*blood -MH - Cardiovascular Diseases/*blood/diagnosis/etiology -MH - Humans -MH - Kidney Failure, Chronic/*blood/complications -MH - Natriuretic Peptide, Brain/*blood -MH - Peptide Fragments/blood -MH - Troponin T/*blood -RF - 93 -EDAT- 2008/03/07 09:00 -MHDA- 2008/10/08 09:00 -CRDT- 2008/03/07 09:00 -PHST- 2008/03/07 09:00 [pubmed] -PHST- 2008/10/08 09:00 [medline] -PHST- 2008/03/07 09:00 [entrez] -AID - ASN.2008010012 [pii] -AID - 10.1681/ASN.2008010012 [doi] -PST - ppublish -SO - J Am Soc Nephrol. 2008 Sep;19(9):1643-52. doi: 10.1681/ASN.2008010012. Epub 2008 - Mar 5. - -PMID- 21633726 -OWN - NLM -STAT- MEDLINE -DCOM- 20110927 -LR - 20211020 -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Print) -IS - 1176-6344 (Linking) -VI - 7 -DP - 2011 -TI - Cardiovascular dysfunction in obesity and new diagnostic imaging techniques: the - role of noninvasive image methods. -PG - 287-95 -LID - 10.2147/VHRM.S17801 [doi] -AB - Obesity is a major public health problem affecting adults and children in both - developed and developing countries. This condition often leads to metabolic - syndrome, which increases the risk of cardiovascular disease. A large number of - studies have been carried out to understand the pathogenesis of cardiovascular - dysfunction in obese patients. Endothelial dysfunction plays a key role in the - progression of atherosclerosis and the development of coronary artery disease, - hypertension and congestive heart failure. Noninvasive methods in the field of - cardiovascular imaging, such as measuring intima-media thickness, flow-mediated - dilatation, tissue Doppler, and strain, and strain rate, constitute new tools for - the early detection of cardiac and vascular dysfunction. These techniques will - certainly enable a better evaluation of initial cardiovascular injury and allow - the correct, timely management of obese patients. The present review summarizes - the main aspects of cardiovascular dysfunction in obesity and discusses the - application of recent noninvasive imaging methods for the early detection of - cardiovascular alterations. -FAU - Barbosa, José Augusto A -AU - Barbosa JA -AD - Department of Pediatrics, Faculty of Medicine, Federal University of Minas - Gerais, Belo Horizonte, Minas Gerais, Brazil. jalmeidabarbosa@uol.com.br -FAU - Rodrigues, Alexandre B -AU - Rodrigues AB -FAU - Mota, Cleonice Carvalho C -AU - Mota CC -FAU - Barbosa, Márcia M -AU - Barbosa MM -FAU - Simões e Silva, Ana C -AU - Simões e Silva AC -LA - eng -PT - Journal Article -PT - Review -DEP - 20110510 -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -SB - IM -MH - Cardiovascular Diseases/*diagnosis/*etiology -MH - Diagnostic Imaging/methods -MH - *Diagnostic Techniques, Cardiovascular -MH - Humans -MH - Obesity/*complications -PMC - PMC3104606 -OTO - NOTNLM -OT - cardiovascular risk -OT - endothelium dysfunction -OT - obesity -OT - strain and strain rate -OT - tissue Doppler -EDAT- 2011/06/03 06:00 -MHDA- 2011/09/29 06:00 -PMCR- 2011/05/10 -CRDT- 2011/06/03 06:00 -PHST- 2011/05/10 00:00 [received] -PHST- 2011/06/03 06:00 [entrez] -PHST- 2011/06/03 06:00 [pubmed] -PHST- 2011/09/29 06:00 [medline] -PHST- 2011/05/10 00:00 [pmc-release] -AID - vhrm-7-287 [pii] -AID - 10.2147/VHRM.S17801 [doi] -PST - ppublish -SO - Vasc Health Risk Manag. 2011;7:287-95. doi: 10.2147/VHRM.S17801. Epub 2011 May - 10. - -PMID- 24159346 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20220408 -IS - 1741-427X (Print) -IS - 1741-4288 (Electronic) -IS - 1741-427X (Linking) -VI - 2013 -DP - 2013 -TI - Tai chi chuan in medicine and health promotion. -PG - 502131 -LID - 10.1155/2013/502131 [doi] -LID - 502131 -AB - Tai Chi Chuan (Tai Chi) is a Chinese traditional mind-body exercise and recently, - it becomes popular worldwide. During the practice of Tai Chi, deep diaphragmatic - breathing is integrated into body motions to achieve a harmonious balance between - body and mind and to facilitate the flow of internal energy (Qi). Participants - can choose to perform a complete set of Tai Chi or selected movements according - to their needs. Previous research substantiates that Tai Chi has significant - benefits to health promotion, and regularly practicing Tai Chi improves aerobic - capacity, muscular strength, balance, health-related quality of life, and - psychological well-being. Recent studies also prove that Tai Chi is safe and - effective for patients with neurological diseases (e.g., stroke, Parkinson's - disease, traumatic brain injury, multiple sclerosis, cognitive dysfunction), - rheumatological disease (e.g., rheumatoid arthritis, ankylosing spondylitis, and - fibromyalgia), orthopedic diseases (e.g., osteoarthritis, osteoporosis, low-back - pain, and musculoskeletal disorder), cardiovascular diseases (e.g., acute - myocardial infarction, coronary artery bypass grafting surgery, and heart - failure), chronic obstructive pulmonary diseases, and breast cancers. Tai Chi is - an aerobic exercise with mild-to-moderate intensity and is appropriate for - implementation in the community. This paper reviews the existing literature on - Tai Chi and introduces its health-promotion effect and the potential clinical - applications. -FAU - Lan, Ching -AU - Lan C -AD - Department of Physical Medicine and Rehabilitation, National Taiwan University - Hospital, 7 Chung-Shan South Road and National Taiwan University, College of - Medicine, Taipei 100, Taiwan. -FAU - Chen, Ssu-Yuan -AU - Chen SY -FAU - Lai, Jin-Shin -AU - Lai JS -FAU - Wong, Alice May-Kuen -AU - Wong AM -LA - eng -PT - Journal Article -PT - Review -DEP - 20130912 -PL - United States -TA - Evid Based Complement Alternat Med -JT - Evidence-based complementary and alternative medicine : eCAM -JID - 101215021 -PMC - PMC3789446 -EDAT- 2013/10/26 06:00 -MHDA- 2013/10/26 06:01 -PMCR- 2013/09/12 -CRDT- 2013/10/26 06:00 -PHST- 2013/04/16 00:00 [received] -PHST- 2013/06/29 00:00 [accepted] -PHST- 2013/10/26 06:00 [entrez] -PHST- 2013/10/26 06:00 [pubmed] -PHST- 2013/10/26 06:01 [medline] -PHST- 2013/09/12 00:00 [pmc-release] -AID - 10.1155/2013/502131 [doi] -PST - ppublish -SO - Evid Based Complement Alternat Med. 2013;2013:502131. doi: 10.1155/2013/502131. - Epub 2013 Sep 12. - -PMID- 19355911 -OWN - NLM -STAT- MEDLINE -DCOM- 20090526 -LR - 20190923 -IS - 1566-5240 (Print) -IS - 1566-5240 (Linking) -VI - 9 -IP - 3 -DP - 2009 Apr -TI - Cell therapy for myocardial regeneration. -PG - 287-98 -AB - Cardiovascular disease is one of the leading causes of morbidity and mortality - around the world. Even after successful revascularization in coronary artery - disease, cell death continues and the loss of cardiomyocytes eventually leads to - progressive ventricular dilation and heart dysfunction. The notion of repairing - or regenerating lost myocardium via cell-based therapies remains highly - appealing. The recent identification of human stem cells, including embryonic - stem cells and adult stem cells, has raised optimism for the development of a new - therapy. This new cell-therapy and the concept of regenerative medicine is aimed - at restoring the damaged myocardium, both vasculature and muscle. Here, we review - the stem cell field and other available cell sources for myocardial regeneration, - focusing on the up-to-date status of stem cell biology, recent laboratory - advances and the current clinical applications. In addition, the limitations and - practical hurdles that need urgent solution before more extensive applications - become feasible are also discussed. -FAU - Liu, Jia -AU - Liu J -AD - Shandong Provincial Hospital, Shandong University, Jinan, China. -FAU - Sluijter, Joost P G -AU - Sluijter JP -FAU - Goumans, Marie-Jose -AU - Goumans MJ -FAU - Smits, Anke M -AU - Smits AM -FAU - van der Spoel, Tycho -AU - van der Spoel T -FAU - Nathoe, Hendrik -AU - Nathoe H -FAU - Doevendans, Pieter A -AU - Doevendans PA -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Curr Mol Med -JT - Current molecular medicine -JID - 101093076 -SB - IM -MH - Adipocytes, Brown/physiology -MH - Bone Marrow Cells/cytology/physiology -MH - Cardiovascular Diseases/pathology/*therapy -MH - *Cell- and Tissue-Based Therapy -MH - Clinical Trials as Topic -MH - Embryonic Stem Cells/cytology/physiology -MH - Humans -MH - Myoblasts/cytology/physiology -MH - *Myocardium/cytology/metabolism -MH - Regeneration/*physiology -MH - Regenerative Medicine/methods -MH - Stem Cell Transplantation -RF - 121 -EDAT- 2009/04/10 09:00 -MHDA- 2009/05/27 09:00 -CRDT- 2009/04/10 09:00 -PHST- 2009/04/10 09:00 [entrez] -PHST- 2009/04/10 09:00 [pubmed] -PHST- 2009/05/27 09:00 [medline] -AID - 10.2174/156652409787847218 [doi] -PST - ppublish -SO - Curr Mol Med. 2009 Apr;9(3):287-98. doi: 10.2174/156652409787847218. - -PMID- 22525440 -OWN - NLM -STAT- MEDLINE -DCOM- 20120810 -LR - 20231004 -IS - 1420-3049 (Electronic) -IS - 1420-3049 (Linking) -VI - 17 -IP - 4 -DP - 2012 Apr 23 -TI - Dynamic action of carotenoids in cardioprotection and maintenance of cardiac - health. -PG - 4755-69 -LID - 10.3390/molecules17044755 [doi] -AB - Oxidative stress has been considered universally and undeniably implicated in the - pathogenesis of all major diseases, including those of the cardiovascular system. - Oxidative stress activate transcriptional messengers, such as nuclear factor-κB, - tangibly contributing to endothelial dysfunction, the initiation and progression - of atherosclerosis, irreversible damage after ischemic reperfusion, and even - arrhythmia, such as atrial fibrillation. Evidence is rapidly accumulating to - support the role of reactive oxygen species (ROS) and reactive nitrogen species - (RNS) as intracellular signaling molecules. Despite this connection between - oxidative stress and cardiovascular disease (CVD), there are currently no - recognized therapeutic interventions to address this important unmet need. - Antioxidants that provide a broad, "upstream" approach via ROS/RNS quenching or - free radical chain breaking seem an appropriate therapeutic option based on - epidemiologic, dietary, and in vivo animal model data. Short-term dietary - intervention trials suggest that diets rich in fruit and vegetable intake lead to - improvements in coronary risk factors and reduce cardiovascular mortality. - Carotenoids are such abundant, plant-derived, fat-soluble pigments that functions - as antioxidants. They are stored in the liver or adipose tissue, and are lipid - soluble by becoming incorporated into plasma lipoprotein particles during - transport. For these reasons, carotenoids may represent one plausible mechanism - by which fruits and vegetables reduce the risk of chronic diseases as - cardiovascular disease (CVD). This review paper outlines the role of carotenoids - in maintaining cardiac health and cardioprotection mediated by several mechanisms - including redox signaling. -FAU - Agarwal, Mahesh -AU - Agarwal M -AD - Department of Biotechnology, School of Life Sciences, Pondicherry University, - Puducherry-605014, India. mhsh.agarwal@gmail.com -FAU - Parameswari, Royapuram P -AU - Parameswari RP -FAU - Vasanthi, Hannah R -AU - Vasanthi HR -FAU - Das, Dipak K -AU - Das DK -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Retracted Publication -PT - Review -DEP - 20120423 -PL - Switzerland -TA - Molecules -JT - Molecules (Basel, Switzerland) -JID - 100964009 -RN - 0 (Antioxidants) -RN - 0 (Cardiotonic Agents) -RN - 36-88-4 (Carotenoids) -SB - IM -RIN - Molecules. 2014 Mar 25;19(3):3850. doi: 10.3390/molecules19033850. PMID: 24896014 -MH - Animals -MH - Antioxidants/chemistry/*pharmacology/therapeutic use -MH - Cardiotonic Agents/chemistry/*pharmacology/therapeutic use -MH - Carotenoids/chemistry/*pharmacology/therapeutic use -MH - Cell Communication -MH - Endothelial Cells/metabolism -MH - Gap Junctions/metabolism -MH - Heart/*drug effects -MH - Humans -MH - Oxidation-Reduction/drug effects -MH - Reperfusion Injury/drug therapy/metabolism -MH - Signal Transduction -PMC - PMC6269032 -EDAT- 2012/04/25 06:00 -MHDA- 2012/08/11 06:00 -PMCR- 2012/04/23 -CRDT- 2012/04/25 06:00 -PHST- 2012/02/06 00:00 [received] -PHST- 2012/03/28 00:00 [revised] -PHST- 2012/04/05 00:00 [accepted] -PHST- 2012/04/25 06:00 [entrez] -PHST- 2012/04/25 06:00 [pubmed] -PHST- 2012/08/11 06:00 [medline] -PHST- 2012/04/23 00:00 [pmc-release] -AID - molecules17044755 [pii] -AID - molecules-17-04755 [pii] -AID - 10.3390/molecules17044755 [doi] -PST - epublish -SO - Molecules. 2012 Apr 23;17(4):4755-69. doi: 10.3390/molecules17044755. - -PMID- 19167272 -OWN - NLM -STAT- MEDLINE -DCOM- 20090623 -LR - 20090323 -IS - 1471-4892 (Print) -IS - 1471-4892 (Linking) -VI - 9 -IP - 2 -DP - 2009 Apr -TI - Druggable targets for sudden cardiac death prevention: lessons from the past and - strategies for the future. -PG - 146-53 -LID - 10.1016/j.coph.2008.12.005 [doi] -AB - Sudden cardiac death (SCD) is most commonly caused by ventricular fibrillation - (VF). The single largest cohort of victims is the population with little or no - prior overt heart disease. Effective prevention will require long-term - prophylaxis by drugs in large numbers of people identified by risk factors. This - means that safe as well as effective drugs are required. Drugs with overt effects - on cardiac electrophysiology have failed in the clinic owing to poor - effectiveness and/or adverse effects. This article examines possible new drug - targets. We have focused on acute myocardial ischaemia as it is the most - strikingly proarrhythmic pathology, and the most common cause of coronary artery - disease-related VF and SCD according to inferences from epidemiology, drug trials - and decades of animal research. To set the scene we have briefly explored drugs - that have failed in the clinic in order to identify possible targets that have - been overlooked or underexploited. We conclude that the best strategy is - identification of pathology-specific targets that render drugs active only where - and when their action is required. -FAU - Clements-Jewery, Hugh -AU - Clements-Jewery H -AD - West Virginia School of Osteopathic Medicine, Lewisburg, West Virginia, USA. -FAU - Andrag, Ellen -AU - Andrag E -FAU - Curtis, Michael J -AU - Curtis MJ -LA - eng -GR - British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090121 -PL - England -TA - Curr Opin Pharmacol -JT - Current opinion in pharmacology -JID - 100966133 -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Ion Channels) -SB - IM -MH - Animals -MH - Anti-Arrhythmia Agents/*pharmacology/*therapeutic use -MH - Clinical Trials as Topic -MH - Death, Sudden, Cardiac/etiology/*prevention & control -MH - Drug Delivery Systems -MH - Drug Discovery -MH - Gap Junctions/drug effects -MH - Humans -MH - Ion Channels/antagonists & inhibitors -MH - Myocardial Ischemia/complications -MH - Ventricular Fibrillation/drug therapy/*prevention & control -RF - 75 -EDAT- 2009/01/27 09:00 -MHDA- 2009/06/24 09:00 -CRDT- 2009/01/27 09:00 -PHST- 2008/11/17 00:00 [received] -PHST- 2008/12/02 00:00 [revised] -PHST- 2008/12/04 00:00 [accepted] -PHST- 2009/01/27 09:00 [entrez] -PHST- 2009/01/27 09:00 [pubmed] -PHST- 2009/06/24 09:00 [medline] -AID - S1471-4892(08)00204-X [pii] -AID - 10.1016/j.coph.2008.12.005 [doi] -PST - ppublish -SO - Curr Opin Pharmacol. 2009 Apr;9(2):146-53. doi: 10.1016/j.coph.2008.12.005. Epub - 2009 Jan 21. - -PMID- 23622905 -OWN - NLM -STAT- MEDLINE -DCOM- 20130618 -LR - 20130429 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 165 -IP - 5 -DP - 2013 May -TI - Thienopyridine efficacy and cigarette smoking status. -PG - 693-703 -LID - S0002-8703(13)00149-X [pii] -LID - 10.1016/j.ahj.2012.12.024 [doi] -AB - Dual antiplatelet therapy with aspirin and a P2Y12 receptor blocker is an - established regimen to reduce the risk of ischemic event occurrence in patients - with high-risk cardiovascular (CV) disease. Cigarette smoking is an important - cardiovascular risk factor. However, several investigators have reported what may - be termed a "new" "smoker's paradox", whereby clopidogrel-treated nonsmokers - appear to have either less or no CV-event reduction when compared to the - substantial CV-event reduction in clopidogrel-treated smokers based on several - large-scale trials. This "smoker's paradox" observed in multiple clinical outcome - studies is also supported by emerging "real-world" data that also suggest - clopidogrel nonsmokers do not fare as well as smokers treated with clopidogrel. - In support of the new "smoker's paradox", pharmacodynamic studies have also shown - that smoking status influences clopidogrel responsiveness in healthy volunteers, - acute coronary syndrome patients, and patients treated with percutaneous coronary - intervention. Finally, there is a substantial, albeit not entirely consistent, - body of pharmacodynamic and clinical outcome data supporting a reduced - antiplatelet effect of clopidogrel in non-smokers as compared to smokers. The - clinical relevance of this interaction has never been demonstrated in a - prospective trial. The focus of this review is to critically evaluate the - reported interaction between cigarette smoking status and thienopyridine - efficacy. -CI - Copyright © 2013 Mosby, Inc. All rights reserved. -FAU - Bliden, Kevin P -AU - Bliden KP -AD - Sinai Center for Thrombosis Research, Baltimore, MD 21215, USA. -FAU - Baker, Brian A -AU - Baker BA -FAU - Nolin, Thomas D -AU - Nolin TD -FAU - Jeong, Young-Hoon -AU - Jeong YH -FAU - Bailey, William L -AU - Bailey WL -FAU - Tantry, Udaya S -AU - Tantry US -FAU - Gurbel, Paul A -AU - Gurbel PA -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130326 -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -RN - 0 (Pyridines) -RN - 0 (thienopyridine) -SB - IM -MH - Cardiovascular Diseases/etiology/*prevention & control -MH - Humans -MH - Pyridines/*therapeutic use -MH - Risk Factors -MH - Smoking/*adverse effects -MH - Treatment Outcome -EDAT- 2013/04/30 06:00 -MHDA- 2013/06/19 06:00 -CRDT- 2013/04/30 06:00 -PHST- 2012/09/05 00:00 [received] -PHST- 2012/12/16 00:00 [accepted] -PHST- 2013/04/30 06:00 [entrez] -PHST- 2013/04/30 06:00 [pubmed] -PHST- 2013/06/19 06:00 [medline] -AID - S0002-8703(13)00149-X [pii] -AID - 10.1016/j.ahj.2012.12.024 [doi] -PST - ppublish -SO - Am Heart J. 2013 May;165(5):693-703. doi: 10.1016/j.ahj.2012.12.024. Epub 2013 - Mar 26. - -PMID- 17450683 -OWN - NLM -STAT- MEDLINE -DCOM- 20070531 -LR - 20131121 -IS - 0001-4079 (Print) -IS - 0001-4079 (Linking) -VI - 190 -IP - 7 -DP - 2006 Oct -TI - [Leukotrienes: potential therapeutic targets in cardiovascular diseases]. -PG - 1511-8; discussion 1518-21 -AB - Leukotrienes are potent inflammatory mediators synthesized locally within the - cardiovascular system through the 5-lipoxygenase pathway of arachidonic acid - metabolism. The leukotrienes, consisting of dihydroxy leukotriene LTB4 and the - cysteinyl leukotrienes LTC4, LTD4 and LTE4, act by targeting cell surface - receptors expressed on inflammatory cells and on structural cells of vessel - walls. LTB, induces leukocyte activation and chemotaxis via high- and - low-affinity receptor subtypes (BLT1 and BLT2), respectively. Recently, BLT, - receptors were found on human vascular smooth muscle cells, inducing their - migration and proliferation. Cysteinyl leukotrienes are vasoconstrictors and - induce endothelium-dependent vascular responses through the CysLT, and CysLT2 - receptor subtypes. There is also pharmacological evidence for the existence of - further CysLT receptor subtypes. Taken together, experimental and genetic studies - suggest a major role of leukotrienes in atherosclerosis and in its ischemic - complications such as acute coronary syndromes and stroke. Furthermore, the - effects on vascular smooth muscle cells suggest a role in the vascular remodeling - observed after coronary angioplasty, as well as in aortic aneurysm. Further - experimental and clinical studies are needed to determine the potential of - therapeutic strategies targeting the leukotriene pathway in cardiovascular - disease. -FAU - Bäck, Magnus -AU - Bäck M -AD - INSERM unité 698, CHU Xavier-Bichat, 16 rue Henri Huchard, 75018 Paris. -LA - fre -PT - Comparative Study -PT - English Abstract -PT - Journal Article -PT - Review -TT - Les leucotriènes: des cibles thérapeutiques potentielles dans le traitement des - maladies cardiovasculaires. -PL - Netherlands -TA - Bull Acad Natl Med -JT - Bulletin de l'Academie nationale de medecine -JID - 7503383 -RN - 0 (Leukotriene Antagonists) -RN - 0 (Leukotrienes) -RN - 0 (Receptors, Leukotriene) -RN - 1HGW4DR56D (Leukotriene B4) -RN - 27YG812J1I (Arachidonic Acid) -RN - 2CU6TT9V48 (Leukotriene C4) -RN - 73836-78-9 (Leukotriene D4) -RN - 75715-89-8 (Leukotriene E4) -SB - IM -MH - Angioplasty, Balloon, Coronary -MH - Animals -MH - Aortic Aneurysm/etiology/physiopathology -MH - Arachidonic Acid/metabolism -MH - Atherosclerosis/physiopathology -MH - Cardiovascular Diseases/*drug therapy/etiology/metabolism/*physiopathology -MH - Cell Movement -MH - Coronary Restenosis/physiopathology -MH - Disease Models, Animal -MH - Guinea Pigs -MH - Humans -MH - Hypertension/physiopathology -MH - Leukotriene Antagonists/*therapeutic use -MH - Leukotriene B4/metabolism/physiology -MH - Leukotriene C4/metabolism/physiology -MH - Leukotriene D4/metabolism/physiology -MH - Leukotriene E4/metabolism/physiology -MH - Leukotrienes/blood/metabolism/*physiology/urine -MH - Mice -MH - Muscle, Smooth, Vascular/metabolism/physiology -MH - Rats -MH - Receptors, Leukotriene/*physiology -MH - Stroke/physiopathology -RF - 17 -EDAT- 2007/04/25 09:00 -MHDA- 2007/06/01 09:00 -CRDT- 2007/04/25 09:00 -PHST- 2007/04/25 09:00 [pubmed] -PHST- 2007/06/01 09:00 [medline] -PHST- 2007/04/25 09:00 [entrez] -PST - ppublish -SO - Bull Acad Natl Med. 2006 Oct;190(7):1511-8; discussion 1518-21. - -PMID- 17164132 -OWN - NLM -STAT- MEDLINE -DCOM- 20070402 -LR - 20250529 -IS - 1098-8823 (Print) -IS - 1098-8823 (Linking) -VI - 82 -IP - 1-4 -DP - 2007 Jan -TI - Role of epoxyeicosatrienoic acids in protecting the myocardium following - ischemia/reperfusion injury. -PG - 50-9 -AB - Cardiomyocyte injury following ischemia-reperfusion can lead to cell death and - result in cardiac dysfunction. A wide range of cardioprotective factors have been - studied to date, but only recently has the cardioprotective role of fatty acids, - specifically arachidonic acid (AA), been investigated. This fatty acid can be - found in the membranes of cells in an inactive state and can be released by - phospholipases in response to several stimuli, such as ischemia. The metabolism - of AA involves the cycloxygenase (COX) and lipoxygenase (LOX) pathways, as well - as the less well characterized cytochrome P450 (CYP) monooxygenase pathway. - Current research suggests important differences with respect to the - cardiovascular actions of specific CYP mediated arachidonic acid metabolites. For - example, CYP mediated hydroxylation of AA produces 20-hydroxyeicosatetraenoic - acid (20-HETE) which has detrimental effects in the heart during ischemia, - pro-inflammatory effects during reperfusion and potent vasoconstrictor effects in - the coronary circulation. Conversely, epoxidation of AA by CYP enzymes generates - 5,6-, 8,9-, 11,12- and 14,15-epoxyeicosatrienoic acids (EETs) that have been - shown to reduce ischemia-reperfusion injury, have potent anti-inflammatory - effects within the vasculature, and are potent vasodilators in the coronary - circulation. This review aims to provide an overview of current data on the role - of these CYP pathways in the heart with an emphasis on their involvement as - mediators of ischemia-reperfusion injury. A better understanding of these - relationships will facilitate identification of novel targets for the prevention - and/or treatment of ischemic heart disease, a major worldwide public health - problem. -FAU - Seubert, John M -AU - Seubert JM -AD - Faculty of Pharmacy and Pharmaceutical Sciences, 3126 Dentistry/Pharmacy Centre, - University of Alberta, Edmonton, AB, Canada T6G 2N8. - jseubert@pharmacy.ualberta.ca -FAU - Zeldin, Darryl C -AU - Zeldin DC -FAU - Nithipatikom, Kasem -AU - Nithipatikom K -FAU - Gross, Garrett J -AU - Gross GJ -LA - eng -GR - Z01 ES025034/ImNIH/Intramural NIH HHS/United States -PT - Journal Article -PT - Review -DEP - 20060710 -PL - United States -TA - Prostaglandins Other Lipid Mediat -JT - Prostaglandins & other lipid mediators -JID - 9808648 -RN - 0 (Epoxy Compounds) -RN - 0 (Mitochondrial Membrane Transport Proteins) -RN - 0 (Mitochondrial Permeability Transition Pore) -RN - 0 (Potassium Channels) -RN - 9035-51-2 (Cytochrome P-450 Enzyme System) -RN - EC 1.13.- (Oxygenases) -RN - EC 1.14.14.1 (Cytochrome P-450 CYP2J2) -RN - EC 3.3.2.- (Epoxide Hydrolases) -RN - FC398RK06S (8,11,14-Eicosatrienoic Acid) -SB - IM -MH - 8,11,14-Eicosatrienoic Acid/*analogs & derivatives/therapeutic use -MH - Animals -MH - Cytochrome P-450 CYP2J2 -MH - Cytochrome P-450 Enzyme System/metabolism -MH - Epoxide Hydrolases/metabolism -MH - Epoxy Compounds/therapeutic use -MH - Humans -MH - Mitochondrial Membrane Transport Proteins/physiology -MH - Mitochondrial Permeability Transition Pore -MH - Myocardial Reperfusion Injury/*prevention & control -MH - Oxygenases/metabolism -MH - Potassium Channels/drug effects/physiology -MH - Signal Transduction -PMC - PMC2077836 -MID - NIHMS33501 -EDAT- 2006/12/14 09:00 -MHDA- 2007/04/03 09:00 -PMCR- 2007/11/14 -CRDT- 2006/12/14 09:00 -PHST- 2006/04/13 00:00 [received] -PHST- 2006/05/11 00:00 [accepted] -PHST- 2006/12/14 09:00 [pubmed] -PHST- 2007/04/03 09:00 [medline] -PHST- 2006/12/14 09:00 [entrez] -PHST- 2007/11/14 00:00 [pmc-release] -AID - S1098-8823(06)00053-0 [pii] -AID - 10.1016/j.prostaglandins.2006.05.017 [doi] -PST - ppublish -SO - Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):50-9. doi: - 10.1016/j.prostaglandins.2006.05.017. Epub 2006 Jul 10. - -PMID- 18854743 -OWN - NLM -STAT- MEDLINE -DCOM- 20081117 -LR - 20220408 -IS - 0263-6352 (Print) -IS - 0263-6352 (Linking) -VI - 26 -IP - 11 -DP - 2008 Nov -TI - Sexual dysfunction: the 'prima ballerina' of hypertension-related quality-of-life - complications. -PG - 2074-84 -LID - 10.1097/HJH.0b013e32830dd0c6 [doi] -AB - Sexual dysfunction is currently considered a serious quality-of-life-related - health problem, exerting a major impact on patients' and their sexual partners' - life. Available data indicate that essential hypertension is a risk factor for - sexual dysfunction, as male and female sexual dysfunction is more prevalent in - hypertensive patients than normotensive individuals. Several mechanisms have been - implicated in the pathogenesis of sexual dysfunction in hypertensive patients, - and major determinants include severity and duration of hypertension, age, and - antihypertensive therapy. Female sexual dysfunction, although more frequent than - its male counterpart, remains largely under-recognized. Older antihypertensive - drugs (diuretics, beta-blockers, centrally acting) exert negative results, - whereas newer drugs have either neutral (calcium antagonists, - angiotensin-converting enzyme inhibitors) or beneficial effects (angiotensin - receptor blockers). Erectile dysfunction is related to ischemic heart disease and - might be an 'early therapeutic window' of asymptomatic coronary artery disease. - It seems of utmost importance for every physician treating hypertensive patients - to become familiar with sexual dysfunction (through better education and specific - seminars) for the proper management of these patients. -FAU - Manolis, Athanasios -AU - Manolis A -AD - Department of Cardiology, Asklepeion Hospital, Athens, Greece. -FAU - Doumas, Michael -AU - Doumas M -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - J Hypertens -JT - Journal of hypertension -JID - 8306882 -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Antihypertensive Agents/adverse effects -MH - Erectile Dysfunction/etiology/physiopathology/psychology -MH - Female -MH - Humans -MH - Hypertension/*complications/physiopathology/*psychology -MH - Male -MH - Penile Erection/physiology -MH - *Quality of Life -MH - Sexual Dysfunction, Physiological/*etiology/physiopathology/*psychology -RF - 144 -EDAT- 2008/10/16 09:00 -MHDA- 2008/11/18 09:00 -CRDT- 2008/10/16 09:00 -PHST- 2008/10/16 09:00 [pubmed] -PHST- 2008/11/18 09:00 [medline] -PHST- 2008/10/16 09:00 [entrez] -AID - 00004872-200811000-00002 [pii] -AID - 10.1097/HJH.0b013e32830dd0c6 [doi] -PST - ppublish -SO - J Hypertens. 2008 Nov;26(11):2074-84. doi: 10.1097/HJH.0b013e32830dd0c6. - -PMID- 18929228 -OWN - NLM -STAT- MEDLINE -DCOM- 20090211 -LR - 20081020 -IS - 1558-2264 (Electronic) -IS - 0733-8651 (Linking) -VI - 26 -IP - 4 -DP - 2008 Nov -TI - Angiotensin receptor blockers: novel role in high-risk patients. -PG - 507-26 -LID - 10.1016/j.ccl.2008.07.001 [doi] -AB - The identification of patients at high risk for cardiovascular events is - imperative in the reduction of cardiovascular mortality and morbidity. Although - coronary artery disease, peripheral arterial disease, cerebrovascular disease, - hypertension, and diabetes mellitus contribute to the risk of developing - cardiovascular events, we are now faced with emerging fronts because of an - increase in life expectancy and the epidemic of hypertension, obesity, metabolic - syndrome, and diabetes. Recent data emphasize the beneficial role of - renin-angiotensin-aldosterone system (RAAS) blockers. This article addresses the - role of RAAS activation in the high-risk metabolic milieu and the role of - angiotensin receptor blockers in targeting and inhibiting the RAAS for - cardiovascular protection. -FAU - Javed, Usman -AU - Javed U -AD - Cardiology Section, Cardiovascular Research, UCSF Fresno Medical Education - Program, UCSF School of Medicine, Fresno, CA 93703, USA. -FAU - Deedwania, Prakash C -AU - Deedwania PC -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/pharmacology/*therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/pharmacology/*therapeutic use -MH - Cardiovascular Diseases/*drug therapy/etiology/physiopathology -MH - Diabetes Mellitus, Type 2/prevention & control -MH - Heart Failure/drug therapy -MH - Humans -MH - Hypertension/drug therapy -MH - Kidney Diseases/drug therapy -MH - Myocardial Infarction/drug therapy -MH - *Renin-Angiotensin System/drug effects/physiology -MH - Risk Factors -RF - 90 -EDAT- 2008/10/22 09:00 -MHDA- 2009/02/12 09:00 -CRDT- 2008/10/22 09:00 -PHST- 2008/10/22 09:00 [pubmed] -PHST- 2009/02/12 09:00 [medline] -PHST- 2008/10/22 09:00 [entrez] -AID - S0733-8651(08)00072-6 [pii] -AID - 10.1016/j.ccl.2008.07.001 [doi] -PST - ppublish -SO - Cardiol Clin. 2008 Nov;26(4):507-26. doi: 10.1016/j.ccl.2008.07.001. - -PMID- 19880690 -OWN - NLM -STAT- MEDLINE -DCOM- 20091123 -LR - 20240516 -IS - 1942-5546 (Electronic) -IS - 0025-6196 (Print) -IS - 0025-6196 (Linking) -VI - 84 -IP - 11 -DP - 2009 Nov -TI - Diagnosis and treatment of viral myocarditis. -PG - 1001-9 -LID - 10.1016/S0025-6196(11)60670-8 [doi] -AB - Myocarditis, an inflammatory disease of heart muscle, is an important cause of - dilated cardiomyopathy worldwide. Viral infection is also an important cause of - myocarditis, and the spectrum of viruses known to cause myocarditis has changed - in the past 2 decades. Several new diagnostic methods, such as cardiac magnetic - resonance imaging, are useful for diagnosing myocarditis. Endomyocardial biopsy - may be used for patients with acute dilated cardiomyopathy associated with - hemodynamic compromise, those with life-threatening arrhythmia, and those whose - condition does not respond to conventional supportive therapy. Important - prognostic variables include the degree of left and right ventricular - dysfunction, heart block, and specific histopathological forms of myocarditis. We - review diagnostic and therapeutic strategies for the treatment of viral - myocarditis. English-language publications in PubMed and references from relevant - articles published between January 1, 1985, and August 5, 2008, were analyzed. - Main keywords searched were myocarditis, dilated cardiomyopathy, endomyocardial - biopsy, cardiac magnetic resonance imaging, and immunotherapy. -FAU - Schultz, Jason C -AU - Schultz JC -AD - Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA. -FAU - Hilliard, Anthony A -AU - Hilliard AA -FAU - Cooper, Leslie T Jr -AU - Cooper LT Jr -FAU - Rihal, Charanjit S -AU - Rihal CS -LA - eng -GR - R56 HL056267/HL/NHLBI NIH HHS/United States -PT - Case Reports -PT - Journal Article -PT - Review -PL - England -TA - Mayo Clin Proc -JT - Mayo Clinic proceedings -JID - 0405543 -SB - IM -MH - Academic Medical Centers -MH - Acute Disease -MH - Cardiomyopathy, Dilated/*diagnosis/mortality/*therapy -MH - Combined Modality Therapy -MH - Coronary Angiography -MH - Echocardiography, Doppler -MH - Female -MH - Follow-Up Studies -MH - Humans -MH - Magnetic Resonance Imaging -MH - Minnesota -MH - Myocarditis/diagnosis/mortality/*therapy/*virology -MH - Risk Assessment -MH - Severity of Illness Index -MH - Survival Rate -MH - Treatment Outcome -MH - Ventricular Dysfunction, Left/diagnosis/etiology/therapy -MH - Virus Diseases/*diagnosis/drug therapy/mortality -MH - Young Adult -PMC - PMC2770911 -EDAT- 2009/11/03 06:00 -MHDA- 2009/12/16 06:00 -PMCR- 2010/05/01 -CRDT- 2009/11/03 06:00 -PHST- 2009/11/03 06:00 [entrez] -PHST- 2009/11/03 06:00 [pubmed] -PHST- 2009/12/16 06:00 [medline] -PHST- 2010/05/01 00:00 [pmc-release] -AID - S0025-6196(11)60670-8 [pii] -AID - 0841001 [pii] -AID - 10.1016/S0025-6196(11)60670-8 [doi] -PST - ppublish -SO - Mayo Clin Proc. 2009 Nov;84(11):1001-9. doi: 10.1016/S0025-6196(11)60670-8. - -PMID- 24134325 -OWN - NLM -STAT- MEDLINE -DCOM- 20140520 -LR - 20220316 -IS - 1542-4758 (Electronic) -IS - 1492-7535 (Print) -IS - 1492-7535 (Linking) -VI - 17 Suppl 1 -IP - 0 1 -DP - 2013 Oct -TI - Vascular calcification in end-stage renal disease. -PG - S17-21 -LID - 10.1111/hdi.12084 [doi] -AB - Vascular calcification is highly prevalent in end-stage renal disease and - independently predictive of future cardiovascular events and mortality. - Calcification can occur in both the intimal and medial layers of vasculature, but - medial calcification is the major form in end-stage renal disease. Medial - calcification increases large elastic artery stiffness and pulse-pressure, - promotes left ventricular hypertrophy, reduces perfusion of the coronary - arteries, and ultimately promotes increased cardiovascular mortality via - increased risk of myocardial infarction and heart failure. It results not from a - passive deposition of calcium and phosphate due to increased circulating levels, - but rather is an active cell-mediated process involving vascular smooth muscle - cell apoptosis and vesicle release, a shift in the balance of inhibitors and - promoters of vascular calcification, and vascular smooth muscle cell - differentiation from a contractile to osteochondrogenic phenotype. This - phenotypic shift requires phosphate, as well as the uptake of phosphate by the - sodium-dependent phosphate cotransporter PiT-1, which is upregulated by - proinflammatory cytokines and the uremic milieu. Further research is needed to - determine if targeting these processes can ultimately reduce vascular - calcification in this high cardiovascular risk population. -CI - © 2013 The Authors. Hemodialysis International © 2013 International Society for - Hemodialysis. -FAU - Jablonski, Kristen L -AU - Jablonski KL -AD - Division of Renal Diseases and Hypertension, University of Colorado Denver - Anschutz Medical Center, Aurora, Colorado, USA. -FAU - Chonchol, Michel -AU - Chonchol M -LA - eng -GR - R01 DK094796/DK/NIDDK NIH HHS/United States -GR - R01DK094796-01/DK/NIDDK NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Canada -TA - Hemodial Int -JT - Hemodialysis international. International Symposium on Home Hemodialysis -JID - 101093910 -RN - 0 (Phosphates) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Calcium/metabolism -MH - Cardiovascular Diseases/*metabolism/*pathology -MH - Humans -MH - Kidney Failure, Chronic/*metabolism/*pathology -MH - Phosphates/metabolism -MH - Risk Factors -MH - Vascular Calcification/*metabolism/*pathology -PMC - PMC3813300 -MID - NIHMS517543 -OTO - NOTNLM -OT - Calcium -OT - end-stage renal disease -OT - phosphate -OT - vascular calcification -EDAT- 2013/10/30 06:00 -MHDA- 2014/05/21 06:00 -PMCR- 2014/10/01 -CRDT- 2013/10/19 06:00 -PHST- 2013/10/19 06:00 [entrez] -PHST- 2013/10/30 06:00 [pubmed] -PHST- 2014/05/21 06:00 [medline] -PHST- 2014/10/01 00:00 [pmc-release] -AID - 10.1111/hdi.12084 [doi] -PST - ppublish -SO - Hemodial Int. 2013 Oct;17 Suppl 1(0 1):S17-21. doi: 10.1111/hdi.12084. - -PMID- 21872149 -OWN - NLM -STAT- MEDLINE -DCOM- 20120604 -LR - 20250529 -IS - 1532-8414 (Electronic) -IS - 1071-9164 (Print) -IS - 1071-9164 (Linking) -VI - 17 -IP - 9 -DP - 2011 Sep -TI - Non-symptom-related factors contributing to delay in seeking medical care by - patients with heart failure: a narrative review. -PG - 779-87 -LID - 10.1016/j.cardfail.2011.05.003 [doi] -AB - BACKGROUND: Delay in seeking timely medical care by patients with acute coronary - syndrome and stroke has been well established in the literature, but less is - known about delay in care-seeking behavior by patients with heart failure (HF). - The purpose of this narrative review was to synthesize the literature regarding - non-symptom-related factors that contribute to delay in seeking medical care for - HF symptoms. METHODS AND RESULTS: A literature search of Scopus, Medline, and - Pubmed was conducted for published articles from database inception to July 2009. - Available evidence has shown that non-symptom-related factors, such as HF - severity, HF history, age, and ethnocultural background, were related to delay in - certain studies; however, null results have also been reported. Other - non-symptom-related factors, such as male gender, initial contact with a primary - care physician, arriving in the emergency department by means other than - ambulance, and patient responses such as self-care, low anxiety, and - hopelessness, may play a role in longer delay. CONCLUSIONS: Although this review - identified several non-symptom-related factors that may be implicated in - care-seeking delay, health care professionals should be vigilant in identifying - all high-risk individuals and educating them about warning signs of HF. Moreover, - access to outpatient chronic disease management programs that may have potential - to reduce care-seeking delay behavior should be explored. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Gravely, Shannon -AU - Gravely S -AD - York University Faculty of Health, Toronto, Ontario, Canada. -FAU - Tamim, Hala -AU - Tamim H -FAU - Smith, Judy -AU - Smith J -FAU - Daly, Tamara -AU - Daly T -FAU - Grace, Sherry L -AU - Grace SL -LA - eng -GR - 80489-1/CAPMC/CIHR/Canada -GR - MSH-80489/CAPMC/CIHR/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110616 -PL - United States -TA - J Card Fail -JT - Journal of cardiac failure -JID - 9442138 -SB - IM -MH - Heart Failure/diagnosis/*psychology/*therapy -MH - Humans -MH - Patient Acceptance of Health Care/*psychology -MH - Self Care/methods/*psychology -MH - Time Factors -PMC - PMC4490893 -MID - CAMS4481 -OID - NLM: CAMS4481 -EDAT- 2011/08/30 06:00 -MHDA- 2012/06/05 06:00 -PMCR- 2015/07/03 -CRDT- 2011/08/30 06:00 -PHST- 2010/06/21 00:00 [received] -PHST- 2011/05/03 00:00 [revised] -PHST- 2011/05/05 00:00 [accepted] -PHST- 2011/08/30 06:00 [entrez] -PHST- 2011/08/30 06:00 [pubmed] -PHST- 2012/06/05 06:00 [medline] -PHST- 2015/07/03 00:00 [pmc-release] -AID - S1071-9164(11)00200-4 [pii] -AID - 10.1016/j.cardfail.2011.05.003 [doi] -PST - ppublish -SO - J Card Fail. 2011 Sep;17(9):779-87. doi: 10.1016/j.cardfail.2011.05.003. Epub - 2011 Jun 16. - -PMID- 18373186 -OWN - NLM -STAT- MEDLINE -DCOM- 20081103 -LR - 20161020 -IS - 0920-3206 (Print) -IS - 0920-3206 (Linking) -VI - 22 -IP - 3 -DP - 2008 Jun -TI - Effects of the thiazolidinedione medications on micro- and macrovascular - complications in patients with diabetes--update 2008. -PG - 233-40 -LID - 10.1007/s10557-008-6093-z [doi] -AB - INTRODUCTION: The thiazolidinedione (TZD) drugs, including pioglitazone (Actos) - and rosiglitazone (Avandia), are commonly prescribed in patients with type 2 - diabetes mellitus (T2DM), largely due to their favorable effects on - hyperglycemia, insulin sensitivity, and cardiometabolic profile. However, the - data are sparse assessing the effects of TZDs on micro- and macrovascular disease - risk. DISCUSSION: Although no studies have been published on microvascular - clinical outcomes, both TZDs significantly reduce the urine albumin-to-creatinine - ratio. TZDs have consistently been associated with favorable effects on - atherosclerosis and cardiovascular disease (CVD) risk. Only one study has been - published to date specifically designed to assess the effects of a TZD - (pioglitazone) on macrovascular outcomes, the PROactive trial. In this trial, - pioglitazone versus placebo was associated with a non-significant 10% reduction - in the combined primary endpoint of mortality, coronary and peripheral vascular - events, and revascularizations. No individual trial has been published - specifically assessing the CVD effects of rosiglitazone, but several - meta-analyses and a published interim report from an ongoing trial (RECORD) point - to safety concerns regarding rosiglitazone use and the risk of myocardial - infarctions (MI), leading to amplified warnings in the product labeling for - rosiglitazone to reflect these concerns. CONCLUSION: All published trials and - meta-analyses of TZDs have consistently shown increased risk of heart failure - (HF) with both TZDs, though the actual placebo-subtracted incidence of HF is low - (<0.5% per year). The initiation of either TZD is contraindicated in patients - with NHYA class III or IV HF, and cautions exist for their use in any patient - with heart failure. Much uncertainty remains regarding the aggregate CVD effects - of the TZDs, and several trials are presently underway to further address these - issues. -FAU - Rohatgi, Anand -AU - Rohatgi A -AD - Cardiovascular Division, University of Texas Southwestern Medical Center, Dallas, - TX 75235-9047, USA. -FAU - McGuire, Darren K -AU - McGuire DK -LA - eng -PT - Journal Article -PT - Review -DEP - 20080329 -PL - United States -TA - Cardiovasc Drugs Ther -JT - Cardiovascular drugs and therapy -JID - 8712220 -RN - 0 (Hypoglycemic Agents) -RN - 0 (Thiazolidinediones) -SB - IM -MH - Animals -MH - Diabetes Mellitus, Type 2/*complications/*drug therapy -MH - Diabetic Angiopathies/*prevention & control -MH - Edema/etiology/prevention & control -MH - Heart Failure/etiology/prevention & control -MH - Humans -MH - Hypoglycemic Agents/pharmacology/*therapeutic use -MH - Microcirculation/*drug effects -MH - Thiazolidinediones/pharmacology/*therapeutic use -MH - Treatment Outcome -RF - 82 -EDAT- 2008/04/01 09:00 -MHDA- 2008/11/04 09:00 -CRDT- 2008/04/01 09:00 -PHST- 2008/01/14 00:00 [received] -PHST- 2008/01/24 00:00 [accepted] -PHST- 2008/04/01 09:00 [pubmed] -PHST- 2008/11/04 09:00 [medline] -PHST- 2008/04/01 09:00 [entrez] -AID - 10.1007/s10557-008-6093-z [doi] -PST - ppublish -SO - Cardiovasc Drugs Ther. 2008 Jun;22(3):233-40. doi: 10.1007/s10557-008-6093-z. - Epub 2008 Mar 29. - -PMID- 23082844 -OWN - NLM -STAT- MEDLINE -DCOM- 20140121 -LR - 20130807 -IS - 1440-1681 (Electronic) -IS - 0305-1870 (Linking) -VI - 39 -IP - 12 -DP - 2012 Dec -TI - Obstructive sleep apnoea and cardiovascular complications: perception versus - knowledge. -PG - 995-1003 -LID - 10.1111/1440-1681.12024 [doi] -AB - Epidemiological evidence has confirmed that obstructive sleep apnoea (OSA) - significantly promotes cardiovascular risk, independent of age, sex, race and - other common risk factors for cardiovascular diseases, such as smoking, drinking, - obesity, diabetes mellitus, dyslipidaemia and hypertension. Patients with severe - OSA exhibit a higher prevalence of coronary artery disease, heart failure and - stroke. Despite the tight correlation between sleep apnoea and these - comorbidities, the mechanisms behind increased cardiovascular risk in OSA remain - elusive. Several theories have been postulated, including sympathetic activation, - endothelial dysfunction, oxidative stress and inflammation. The association - between OSA and cardiovascular diseases may be rather complicated and compounded - by the presence of components of metabolic syndrome, such as obesity, - hypertension, diabetes mellitus and dyslipidaemia. The present minireview updates - current knowledge with regard to the cardiovascular sequelae of OSA and the - mechanisms involved. -CI - © 2012 The Authors Clinical and Experimental Pharmacology and Physiology © 2012 - Wiley Publishing Asia Pty Ltd. -FAU - Thomas, Joi J -AU - Thomas JJ -AD - Division of Kinesiology and Health & Biomedical Science, University of Wyoming - College of Health Sciences, Laramie, WY, USA. -FAU - Ren, Jun -AU - Ren J -LA - eng -PT - Journal Article -PT - Review -PL - Australia -TA - Clin Exp Pharmacol Physiol -JT - Clinical and experimental pharmacology & physiology -JID - 0425076 -SB - IM -MH - Cardiovascular Diseases/epidemiology/*etiology/metabolism/physiopathology -MH - Endothelium, Vascular/physiology -MH - Fatty Liver/etiology/metabolism/physiopathology -MH - Humans -MH - Oxidative Stress/physiology -MH - Risk Factors -MH - Sleep Apnea, Obstructive/*complications/epidemiology/metabolism/physiopathology -MH - Sympathetic Nervous System/physiology -OTO - NOTNLM -OT - cardiovascular disease -OT - obstructive sleep apnoea -OT - risk factor -EDAT- 2012/10/23 06:00 -MHDA- 2014/01/22 06:00 -CRDT- 2012/10/23 06:00 -PHST- 2012/03/09 00:00 [received] -PHST- 2012/10/13 00:00 [revised] -PHST- 2012/10/15 00:00 [accepted] -PHST- 2012/10/23 06:00 [entrez] -PHST- 2012/10/23 06:00 [pubmed] -PHST- 2014/01/22 06:00 [medline] -AID - 10.1111/1440-1681.12024 [doi] -PST - ppublish -SO - Clin Exp Pharmacol Physiol. 2012 Dec;39(12):995-1003. doi: - 10.1111/1440-1681.12024. - -PMID- 19567909 -OWN - NLM -STAT- MEDLINE -DCOM- 20090716 -LR - 20240526 -IS - 1756-1833 (Electronic) -IS - 0959-8138 (Print) -IS - 0959-8138 (Linking) -VI - 338 -DP - 2009 Jun 30 -TI - The benefits of statins in people without established cardiovascular disease but - with cardiovascular risk factors: meta-analysis of randomised controlled trials. -PG - b2376 -LID - bmj.b2376 [pii] -LID - 10.1136/bmj.b2376 [doi] -LID - b2376 -AB - OBJECTIVES: To investigate whether statins reduce all cause mortality and major - coronary and cerebrovascular events in people without established cardiovascular - disease but with cardiovascular risk factors, and whether these effects are - similar in men and women, in young and older (>65 years) people, and in people - with diabetes mellitus. DESIGN: Meta-analysis of randomised trials. DATA SOURCES: - Cochrane controlled trials register, Embase, and Medline. Data abstraction Two - independent investigators identified studies on the clinical effects of statins - compared with a placebo or control group and with follow-up of at least one year, - at least 80% or more participants without established cardiovascular disease, and - outcome data on mortality and major cardiovascular disease events. Heterogeneity - was assessed using the Q and I(2) statistics. Publication bias was assessed by - visual examination of funnel plots and the Egger regression test. RESULTS: 10 - trials enrolled a total of 70 388 people, of whom 23 681 (34%) were women and 16 - 078 (23%) had diabetes mellitus. Mean follow-up was 4.1 years. Treatment with - statins significantly reduced the risk of all cause mortality (odds ratio 0.88, - 95% confidence interval 0.81 to 0.96), major coronary events (0.70, 0.61 to - 0.81), and major cerebrovascular events (0.81, 0.71 to 0.93). No evidence of an - increased risk of cancer was observed. There was no significant heterogeneity of - the treatment effect in clinical subgroups. CONCLUSION: In patients without - established cardiovascular disease but with cardiovascular risk factors, statin - use was associated with significantly improved survival and large reductions in - the risk of major cardiovascular events. -FAU - Brugts, J J -AU - Brugts JJ -AD - Department of Cardiology, Erasmus MC Thoraxcenter, 3015 GD, Rotterdam, - Netherlands. j.brugts@erasmusmc.nl -FAU - Yetgin, T -AU - Yetgin T -FAU - Hoeks, S E -AU - Hoeks SE -FAU - Gotto, A M -AU - Gotto AM -FAU - Shepherd, J -AU - Shepherd J -FAU - Westendorp, R G J -AU - Westendorp RG -FAU - de Craen, A J M -AU - de Craen AJ -FAU - Knopp, R H -AU - Knopp RH -FAU - Nakamura, H -AU - Nakamura H -FAU - Ridker, P -AU - Ridker P -FAU - van Domburg, R -AU - van Domburg R -FAU - Deckers, J W -AU - Deckers JW -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -DEP - 20090630 -PL - England -TA - BMJ -JT - BMJ (Clinical research ed.) -JID - 8900488 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -CIN - Ann Intern Med. 2009 Oct 20;151(8):JC4-14. doi: - 10.7326/0003-4819-151-8-200910200-02014. PMID: 19841451 -CIN - Am Fam Physician. 2010 Oct 1;82(7):741. PMID: 20879694 -MH - Age Distribution -MH - Aged -MH - Cardiovascular Diseases/*prevention & control -MH - Cause of Death -MH - Female -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Male -MH - Middle Aged -MH - Odds Ratio -MH - Randomized Controlled Trials as Topic -MH - Risk Factors -MH - Sex Distribution -MH - Treatment Outcome -PMC - PMC2714690 -COIS- Competing interests: AMG is a consultant for Genentech, Kowa, Martek, Merck, and - Merck/Schering-Plough, and serves on the board of directors for Aegerion and - Arisaph. He is a member of DuPont’s health advisory board and serves on the data - safety monitoring board for Novartis. JS carried out consultancy work and - receives support for research from Bristol-Myers Squibb. RGJW receives support - for research from Bristol-Myers Squibb. HN has received travel grants and - speaking honorariums from Sankyo. RHK has received research fees and speaking - honorariums from Pfizer. PR has received research grant support from the National - Heart Lung and Blood Institute, the National Cancer Institute, the Donald W - Reynolds Foundation, the Leducq Foundation, Astra-Zeneca, Novartis, Merck, - Abbott, Roche, and Sanofi-Aventis; consulting fees and lecture fees from - Astra-Zeneca, Novartis, Merck-Schering Plough, Sanofi-Aventis, ISIS, and Vascular - Biogenics; and is listed as a co-inventor on patents held by the Brigham and - Women’s Hospital that relate to the use of inflammatory biomarkers in - cardiovascular disease. These patents have been licensed to Siemens and - Astra-Zeneca. -EDAT- 2009/07/02 09:00 -MHDA- 2009/07/17 09:00 -PMCR- 2009/06/30 -CRDT- 2009/07/02 09:00 -PHST- 2009/07/02 09:00 [entrez] -PHST- 2009/07/02 09:00 [pubmed] -PHST- 2009/07/17 09:00 [medline] -PHST- 2009/06/30 00:00 [pmc-release] -AID - bmj.b2376 [pii] -AID - bruj615047 [pii] -AID - 10.1136/bmj.b2376 [doi] -PST - epublish -SO - BMJ. 2009 Jun 30;338:b2376. doi: 10.1136/bmj.b2376. - -PMID- 16621590 -OWN - NLM -STAT- MEDLINE -DCOM- 20060731 -LR - 20181201 -IS - 1043-6618 (Print) -IS - 1043-6618 (Linking) -VI - 53 -IP - 5 -DP - 2006 May -TI - Therapeutic effects of I(f) blockade: evidence and perspective. -PG - 440-5 -AB - Heart rate slowing has been accepted for decades as a primary therapeutic - approach to prevention (and even to treatment) of angina pectoris. Pure heart - rate slowing has not been achieved with previously available rate-slowing - pharmacological agents (beta adrenergic blockers, certain calcium channel - blockers), all of which have other pharmacological effects that may be beneficial - but also may underlie adverse drug effects. Modulation of heart rate is a - function of variation in the I(f) current, a sodium-potassium mediated membrane - phenomenon that is active physiologically only in the heart's sinoatrial node. - Though the current first was described more than 25 years ago, a practical - pharmacological method for its inhibition only recently has been developed, - tested and approved for use in Europe. The effective drug, ivabradine, has - demonstrated anti-anginal, anti-ischemic efficacy and now is being tested for its - effect on survival in patients with coronary artery disease and impaired left - ventricular function, as well as for heart failure. The data supporting the use - of the drug for angina prevention, and the potential for additional applications, - are reviewed in this article. -FAU - Borer, Jeffrey S -AU - Borer JS -AD - The Division of Cardiovascular Pathophysiology and The Howard Gilman Institute - for Valvular Heart Diseases, Weill Medical College of Cornell University, The New - York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA. - canadad45@aol.com -LA - eng -PT - Journal Article -PT - Review -DEP - 20060328 -PL - Netherlands -TA - Pharmacol Res -JT - Pharmacological research -JID - 8907422 -RN - 0 (Benzazepines) -RN - 0 (Ion Channels) -RN - 3H48L0LPZQ (Ivabradine) -SB - IM -MH - Angina Pectoris/prevention & control -MH - Animals -MH - Benzazepines/adverse effects/*pharmacology/*therapeutic use -MH - Heart Rate/*drug effects -MH - Humans -MH - Ion Channels/*antagonists & inhibitors -MH - Ivabradine -MH - Myocardial Ischemia/*prevention & control -MH - Randomized Controlled Trials as Topic -MH - Ventricular Dysfunction, Left/prevention & control -RF - 31 -EDAT- 2006/04/20 09:00 -MHDA- 2006/08/01 09:00 -CRDT- 2006/04/20 09:00 -PHST- 2006/02/02 00:00 [received] -PHST- 2006/02/17 00:00 [revised] -PHST- 2006/03/10 00:00 [accepted] -PHST- 2006/04/20 09:00 [pubmed] -PHST- 2006/08/01 09:00 [medline] -PHST- 2006/04/20 09:00 [entrez] -AID - S1043-6618(06)00056-9 [pii] -AID - 10.1016/j.phrs.2006.03.017 [doi] -PST - ppublish -SO - Pharmacol Res. 2006 May;53(5):440-5. doi: 10.1016/j.phrs.2006.03.017. Epub 2006 - Mar 28. - -PMID- 17447137 -OWN - NLM -STAT- MEDLINE -DCOM- 20070816 -LR - 20220716 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 12 -IP - 2 -DP - 2007 Jun -TI - Vasodilators in acute heart failure. -PG - 143-7 -AB - Most patients with acute heart failure present with increased left ventricular - filling pressure and high or normal blood pressure; only a minority present with - cardiogenic shock. In this context, therapy with vasodilators in the acute - setting can improve both hemodynamics and symptoms. Vasodilators are usually - given in conjunction with diuretics, although much of the acute effect of loop - diuretics may be due to venodilation. Currently available agents include - nitroglycerin, nitroprusside, and nesiritide. Nitroglycerin relieves pulmonary - congestion primarily through direct venodilation, but may dilate coronary - arteries and increase collateral blood flow at higher doses, an effect desirable - in patients with ischemia. Tachyphylaxis may develop, necessitating incremental - dosing. The major adverse effects of nitrates are hypotension and headache. - Nitroprusside is a balanced arterial and venous vasodilator with a very short - half-life, facilitating rapid titration. Afterload reduction lowers blood - pressure and can increase stroke volume. The major complications of nitroprusside - therapy are hypotension, and toxicity from accumulation of cyanide or - thiocyanate, usually in patients with renal insufficiency treated for more than - 24 h. Nesiritide, a recombinant form of human B-type natriuretic peptide (BNP), - is a venous and arterial vasodilator that may also potentiate the effect of - concomitant diuretics. Hypotension is the most common side effect. In addition, - meta-analyses have suggested that nesiritide may worsen renal function and - decrease survival at 30 days compared to conventional therapies. Resolution of - these concerns awaits completion of appropriately powered prospective clinical - trials. Angiotensin-converting enzyme (ACE) inhibitors have vasodilatory effects, - but intravenous infusion of enalapril within 24 h of ischemic chest pain is not - recommended. Oral ACE inhibition may be used to reduce afterload in other - settings if blood pressure permits. Use of calcium antagonists in acute heart - failure is not recommended. -FAU - Hollenberg, Steven M -AU - Hollenberg SM -AD - Division of Cardiovascular Disease, Cooper University Hospital, One Cooper Plaza, - 366 Dorrance, Camden, NJ 08103, USA. Hollenberg-Steven@cooperhealth.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Diuretics) -RN - 0 (Vasodilator Agents) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - 169D1260KM (Nitroprusside) -RN - G59M7S0WS3 (Nitroglycerin) -SB - IM -MH - Acute Disease -MH - Angiotensin-Converting Enzyme Inhibitors/*therapeutic use -MH - Clinical Trials as Topic -MH - Diuretics/*therapeutic use -MH - Drug Therapy, Combination -MH - Heart Failure/*drug therapy -MH - Humans -MH - Natriuretic Peptide, Brain/therapeutic use -MH - Nitroglycerin/therapeutic use -MH - Nitroprusside/therapeutic use -MH - Treatment Outcome -MH - Vasodilator Agents/*therapeutic use -RF - 23 -EDAT- 2007/04/21 09:00 -MHDA- 2007/08/19 09:00 -CRDT- 2007/04/21 09:00 -PHST- 2007/04/21 09:00 [pubmed] -PHST- 2007/08/19 09:00 [medline] -PHST- 2007/04/21 09:00 [entrez] -AID - 10.1007/s10741-007-9017-2 [doi] -PST - ppublish -SO - Heart Fail Rev. 2007 Jun;12(2):143-7. doi: 10.1007/s10741-007-9017-2. - -PMID- 24500559 -OWN - NLM -STAT- MEDLINE -DCOM- 20150219 -LR - 20140206 -IS - 2352-3840 (Electronic) -IS - 1499-2671 (Linking) -VI - 37 -IP - 5 -DP - 2013 Oct -TI - Diabetic dyslipidemia: from evolving pathophysiological insight to emerging - therapeutic targets. -PG - 319-26 -LID - S1499-2671(13)00948-9 [pii] -LID - 10.1016/j.jcjd.2013.07.062 [doi] -AB - Diabetic dyslipidemia is characterized by hepatic very low density lipoprotein - (VLDL) and intestinal chylomicron overproduction, reduced high density - lipoprotein cholesterol (HDL-C) level, increased propensity of small dense LDL - (sdLDL) and increased postprandial lipemia. This dyslipidemic profile is also - strongly linked to other features of the metabolic syndrome. Diabetic - dyslipidemia is a well-recognized risk factor for atherosclerotic cardiovascular - diseases. Currently, statins remain the first line therapy primarily through - reducing the atherogenic LDL. Clinical trials on other lipid modifying agents - were met with variable success in selective patient populations. Emerging new - insights into the pathophysiology of lipid metabolism, in general, and diabetic - dyslipidemia, in particular, have opened up potentially novel therapeutic - strategies to further reduce the risk associated with diabetic dyslipidemia and - insulin resistant state. -CI - Copyright © 2013 Canadian Diabetes Association. Published by Elsevier Inc. All - rights reserved. -FAU - Ng, Dominic S -AU - Ng DS -AD - Li Ka Shing Knowledge Institute, Keenan Research Center, St. Michael's Hospital, - University of Toronto, Toronto, Ontario, Canada. Electronic address: ngd@smh.ca. -LA - eng -GR - MOP275369/Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Canada -TA - Can J Diabetes -JT - Canadian journal of diabetes -JID - 101148810 -RN - 0 (ABCA1 protein, human) -RN - 0 (ATP Binding Cassette Transporter 1) -RN - 0 (Anticholesteremic Agents) -RN - 0 (Blood Glucose) -RN - 0 (Cholesterol, HDL) -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - ATP Binding Cassette Transporter 1/drug effects -MH - Anticholesteremic Agents/*therapeutic use -MH - Blood Glucose/metabolism -MH - Cholesterol, HDL/blood -MH - Cholesterol, LDL/blood -MH - Coronary Artery Disease/*prevention & control -MH - Diabetes Mellitus, Type 1/blood/drug therapy/*physiopathology -MH - Diabetes Mellitus, Type 2/blood/drug therapy/*physiopathology -MH - Dyslipidemias/blood/drug therapy/*physiopathology -MH - Female -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Insulin Resistance -MH - Male -MH - Postprandial Period -MH - Risk Factors -MH - Treatment Outcome -OTO - NOTNLM -OT - ER stress -OT - HDL -OT - cardiovascular diseases -OT - cholesterol efflux -OT - diabetes -OT - diabète -OT - dyslipidemia -OT - dyslipidémie -OT - efflux du cholestérol -OT - insulin resistance -OT - insulinorésistance -OT - maladies cardiovasculaires -OT - stress du RE -OT - triglycerides -OT - triglycérides -EDAT- 2014/02/07 06:00 -MHDA- 2015/02/20 06:00 -CRDT- 2014/02/07 06:00 -PHST- 2013/05/26 00:00 [received] -PHST- 2013/07/22 00:00 [revised] -PHST- 2013/07/22 00:00 [accepted] -PHST- 2014/02/07 06:00 [entrez] -PHST- 2014/02/07 06:00 [pubmed] -PHST- 2015/02/20 06:00 [medline] -AID - S1499-2671(13)00948-9 [pii] -AID - 10.1016/j.jcjd.2013.07.062 [doi] -PST - ppublish -SO - Can J Diabetes. 2013 Oct;37(5):319-26. doi: 10.1016/j.jcjd.2013.07.062. - -PMID- 20565229 -OWN - NLM -STAT- MEDLINE -DCOM- 20110124 -LR - 20151119 -IS - 1744-764X (Electronic) -IS - 1474-0338 (Linking) -VI - 9 -IP - 5 -DP - 2010 Sep -TI - The cardiovascular risk of tiotropium: is it real? -PG - 783-92 -LID - 10.1517/14740338.2010.500611 [doi] -AB - IMPORTANCE OF THE FIELD: Anticholinergic agents are of noteworthy value in the - treatment of chronic obstructive pulmonary disease (COPD), but concerns have been - raised about a possible association between their use and cardiovascular (CV) - morbidity and mortality. In this review, we have examined whether and why an - anticholinergic agent, and in particular tiotropium, might cause CV risks. AREAS - COVERED IN THIS REVIEW: We first examine the potential pharmacological mechanisms - that justify the CV risk with an anticholinergic agent, and then the main - clinical trials, observational (cohort or case-control) studies, descriptive - reviews and meta-analyses that have looked at the CV risks associated with - long-term tiotropium, which are available in MEDLINE, EMBASE and Cochrane - Controlled Trials Register databases, using the following MeSH, full text and - keyword terms: tiotropium bromide OR Spiriva AND COPD OR chronic obstructive - pulmonary disease. WHAT THE READER WILL GAIN: The almost absolute confidence that - there is no real increased risk for death or CV morbidity during treatment with - this inhaled anticholinergic agent in patients with COPD because of the results - of a large 4-year trial and a robust and extensive analysis of > 19,000 patients - participating in placebo-controlled tiotropium clinical trials. Nonetheless, - because high-risk patients such as those with coronary artery disease, heart - failure, cardiac arrhythmia, hypoxemia requiring daytime oxygen therapy and a - creatinine > 2 mg/dl were excluded from Phase III clinical trials, it is - impossible to exclude these patients from an increased risk of drug-related - cardiac events in a real-world setting. TAKE HOME MESSAGE: Despite the recently - raised concerns about an excess risk of CV adverse events with inhaled - short-acting anticholinergic agents, the risk:benefit ratio of tiotropium bromide - appears still favorable, although it is not known whether high-risk patients are - at an increased risk of drug-related CV events. -FAU - Cazzola, Mario -AU - Cazzola M -AD - University of Rome Tor Vergata, Department of Internal Medicine, Unit of - Respiratory Clinical Pharmacology, Rome, Italy. mario.cazzola@uniroma2.it -FAU - Calzetta, Luigino -AU - Calzetta L -FAU - Matera, Maria Gabriella -AU - Matera MG -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Expert Opin Drug Saf -JT - Expert opinion on drug safety -JID - 101163027 -RN - 0 (Cholinergic Antagonists) -RN - 0 (Receptors, Muscarinic) -RN - 0 (Scopolamine Derivatives) -RN - XX112XZP0J (Tiotropium Bromide) -SB - IM -MH - Administration, Inhalation -MH - Animals -MH - Cardiovascular Diseases/*chemically induced/epidemiology -MH - Case-Control Studies -MH - Cholinergic Antagonists/administration & dosage/*adverse effects/therapeutic use -MH - Clinical Trials as Topic -MH - Cohort Studies -MH - Comorbidity -MH - Disease Susceptibility -MH - Dogs -MH - Heart/drug effects -MH - Humans -MH - Meta-Analysis as Topic -MH - Multicenter Studies as Topic -MH - Parasympathetic Nervous System/drug effects -MH - Pulmonary Disease, Chronic Obstructive/drug therapy/epidemiology -MH - Receptors, Muscarinic/drug effects -MH - Risk -MH - Scopolamine Derivatives/administration & dosage/*adverse effects/therapeutic use -MH - Tiotropium Bromide -EDAT- 2010/06/23 06:00 -MHDA- 2011/01/25 06:00 -CRDT- 2010/06/23 06:00 -PHST- 2010/06/23 06:00 [entrez] -PHST- 2010/06/23 06:00 [pubmed] -PHST- 2011/01/25 06:00 [medline] -AID - 10.1517/14740338.2010.500611 [doi] -PST - ppublish -SO - Expert Opin Drug Saf. 2010 Sep;9(5):783-92. doi: 10.1517/14740338.2010.500611. - -PMID- 17017110 -OWN - NLM -STAT- MEDLINE -DCOM- 20061127 -LR - 20151119 -IS - 1405-9940 (Print) -IS - 1665-1731 (Linking) -VI - 76 Suppl 2 -DP - 2006 Apr-Jun -TI - [Risk marker stratification in coronary acute syndromes]. -PG - S241-8 -AB - Acute coronary syndromes have a heterogeneous clinical presentation with a broad - spectrum for mortality and adverse events. It is mandatory to identify high risk - groups for percutaneous coronary intervention and intensive antithrombotic - treatment or common risk for standard treatment. In contemporaneous medicine it - is important to get adequate risk stratification because the impact of - hospitalary costs, antithrombotic and reperfusion treatment on health systems. - The current pathophysiology of atherosclerosis is moving from a disease secondary - to cholesterol deposit, to an inflammatory disease. In the stratification - process, familiar history, chest pain, ST dynamic abnormalities, left ventricular - wall motion abnormalities, all have predictive value. The association of indirect - endothelial dysfunction, micro or macronecrosis and ventricular dysfunction - markers increase this value. In our experience a close relationship among - abnormal fibrinolysis, inflammation and anticoagulation proteins with adverse - events has been proved in acute coronary syndromes. Other interesting - finding--for it accessibility--in acute myocardial infarction under coronary - percutaneous intervention is persistent ST elevation, leukocytes and fibrinogen - predictive value. In population allelic polymorphisms -455A and -148T and - fibrinogen ( >450 mg/dL) were associated with coronary disease. These - polymorphisms improve risk stratification of coronary disease to establish a - better secondary prevention and treatment. -FAU - Jerjes-Sánchez Díaz, Carlos -AU - Jerjes-Sánchez Díaz C -AD - Servicio de Urgencias, Hospital de Enfermedades Cardiovasculares y del Tórax, - Centro Médico del Norte, Instituto Mexicano del Seguro Social, Monterrey, - Departamento de Biocuimica de la Facultad de Medicina, UANL. - jerjes@prodigy.net.mx -FAU - Comparan Núñez, Alfredo -AU - Comparan Núñez A -FAU - Miguel Canseco, Luis -AU - Miguel Canseco L -FAU - Garza-Ruiz, Angel -AU - Garza-Ruiz A -FAU - García-Sosa, Anabel -AU - García-Sosa A -FAU - Reyes-Cerezo, Esteban -AU - Reyes-Cerezo E -LA - spa -PT - English Abstract -PT - Journal Article -PT - Review -TT - Marcadores en la estratificación de los síndromes coronarios agudos. -PL - Mexico -TA - Arch Cardiol Mex -JT - Archivos de cardiologia de Mexico -JID - 101126728 -RN - 0 (Biomarkers) -SB - IM -MH - Acute Disease -MH - Angina, Unstable/*blood -MH - Biomarkers/blood -MH - Humans -MH - Myocardial Infarction/*blood -MH - Risk Assessment -MH - Syndrome -RF - 14 -EDAT- 2006/10/05 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/10/05 09:00 -PHST- 2006/10/05 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/10/05 09:00 [entrez] -PST - ppublish -SO - Arch Cardiol Mex. 2006 Apr-Jun;76 Suppl 2:S241-8. - -PMID- 22995112 -OWN - NLM -STAT- MEDLINE -DCOM- 20140219 -LR - 20120921 -IS - 1969-6213 (Electronic) -IS - 1774-024X (Linking) -VI - 8 Suppl Q -DP - 2012 Sep -TI - Transcatheter mitral valve interventions: current status and future perspective. -PG - Q53-9 -LID - EIJV8SQA10 [pii] -LID - 10.4244/EIJV8SQA10 [doi] -AB - AIMS: With the recent developments in the field of transcatheter aortic valve - replacement for aortic stenosis there has been a similar advance in the field of - transcatheter mitral valve therapy for mitral regurgitation (MR). Both the - anatomy of the mitral apparatus and the spectrum of pathology of MR are more - complex than for aortic valve disease, and thus the development of MR therapies - has been more complicated and less rapid. METHODS AND RESULTS: The purpose of - this review of recent literature is to provide a synopsis of the present - technologies under development for percutaneous therapy for MR. Leaflet repair - with MitraClip has accrued the largest human experience among the technologies - that are under development, having been used to treat over 6,000 patients. - MitraClip is currently being used in patients with functional MR and at high risk - for conventional surgery. Coronary sinus, or indirect annuloplasty, has the next - largest clinical experience, with several hundred patients treated in trials. - Other MR therapy devices, including several direct annuloplasty approaches, - mitral valve replacement prostheses, and chordal replacement devices, are still - in the earlier phases of development. CONCLUSIONS: The early technological - advances have not only enhanced our understanding of the complex interplay of - different components of the mitral valve apparatus but also promise continued - refinement in our present modalities of treatment and improved clinical outcomes - for future patients. -FAU - Feldman, Ted -AU - Feldman T -AD - NorthShore University HealthSystem, Evanston, IL 60201, USA. - tfeldman@northshore.org -FAU - Ali, Omar -AU - Ali O -LA - eng -PT - Journal Article -PT - Review -PL - France -TA - EuroIntervention -JT - EuroIntervention : journal of EuroPCR in collaboration with the Working Group on - Interventional Cardiology of the European Society of Cardiology -JID - 101251040 -SB - IM -MH - *Cardiac Catheterization/adverse effects/instrumentation -MH - Heart Valve Prosthesis -MH - Heart Valve Prosthesis Implantation/adverse effects/instrumentation/*methods -MH - Humans -MH - Mitral Valve/*physiopathology -MH - Mitral Valve Annuloplasty/adverse effects/instrumentation/*methods -MH - Mitral Valve Insufficiency/physiopathology/*therapy -MH - Prosthesis Design -MH - Treatment Outcome -EDAT- 2013/08/02 06:00 -MHDA- 2014/02/20 06:00 -CRDT- 2012/09/22 06:00 -PHST- 2012/09/22 06:00 [entrez] -PHST- 2013/08/02 06:00 [pubmed] -PHST- 2014/02/20 06:00 [medline] -AID - EIJV8SQA10 [pii] -AID - 10.4244/EIJV8SQA10 [doi] -PST - ppublish -SO - EuroIntervention. 2012 Sep;8 Suppl Q:Q53-9. doi: 10.4244/EIJV8SQA10. - -PMID- 17584049 -OWN - NLM -STAT- MEDLINE -DCOM- 20070710 -LR - 20191110 -IS - 1871-529X (Print) -IS - 1871-529X (Linking) -VI - 7 -IP - 2 -DP - 2007 Jun -TI - Human embryonic stem cell-derived cardiomyocytes for heart therapies. -PG - 145-52 -AB - Cardiovascular diseases remain the leading cause of mortality and morbidity - worldwide. Despite substantial improvements in acute management, survivors of - myocardial infarction often progress to heart failure. Since adult cardiomyocytes - (CMs) do not regenerate, their loss permanently compromises myocardial - contractile function. Heart transplantation is currently the last resort for - end-stage heart failure, but is hampered by a severe shortage of donor organs and - rejection. Cell-based therapies are a promising alternative: Various cell types - such as human fetal CMs, skeletal muscle myoblasts and smooth muscle cells have - been tested but these approaches are also limited by cell availability or side - effects (e.g. due to their non-cardiac identity). In recent years, clinical - studies exploiting adult bone marrow mesenchymal stem cells for transplantation - in patients with coronary artery disease have reported favorable outcomes but - their cardiomyogenic ability is limited. By contrast, human embryonic stem cells - (hESCs), derived from the inner cell mass of blastocyst-stage embryos, are - pluripotent and can self-renew and differentiate into all cell types including - CMs. Furthermore, hESC-derived CMs (hESC-CMs) are viable human heart cells that - can functionally integrate with the recipient organ after transplantation. This - article reviews the current state and hurdles of hESC-CM research, as well as - their therapeutic potentials and limitations. -FAU - Siu, Chung Wah -AU - Siu CW -AD - Department of Cell Biology and Human Anatomy, University of California, Davis, - Sacramento, CA 95817, USA. -FAU - Moore, Jennifer C -AU - Moore JC -FAU - Li, Ronald A -AU - Li RA -LA - eng -GR - F32 HL078330/HL/NHLBI NIH HHS/United States -GR - R01 HL72857/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Cardiovasc Hematol Disord Drug Targets -JT - Cardiovascular & hematological disorders drug targets -JID - 101269160 -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Animals -MH - Calcium/metabolism -MH - Electrophysiology -MH - Embryonic Stem Cells/*physiology/*transplantation -MH - Heart Diseases/*therapy -MH - Humans -MH - Myocardium/cytology -MH - Myocytes, Cardiac/*physiology -MH - Regeneration -RF - 69 -EDAT- 2007/06/23 09:00 -MHDA- 2007/07/11 09:00 -CRDT- 2007/06/23 09:00 -PHST- 2007/06/23 09:00 [pubmed] -PHST- 2007/07/11 09:00 [medline] -PHST- 2007/06/23 09:00 [entrez] -AID - 10.2174/187152907780830851 [doi] -PST - ppublish -SO - Cardiovasc Hematol Disord Drug Targets. 2007 Jun;7(2):145-52. doi: - 10.2174/187152907780830851. - -PMID- 19102435 -OWN - NLM -STAT- MEDLINE -DCOM- 20090113 -LR - 20081223 -IS - 0028-2162 (Print) -IS - 0028-2162 (Linking) -VI - 152 -IP - 48 -DP - 2008 Nov 29 -TI - [Perioperative risk reduction in vascular surgery via cardio-protective - medication]. -PG - 2606-11 -AB - Cardiovascular complications are the leading cause of death after noncardiac - surgery. Preoperative identification of patients with underlying coronary artery - disease is important, and appropriate treatment strategies should be implemented - in these patients in order to reduce the risk of perioperative complications. - Based on recent findings, preoperative risk stratification models have been - developed to identify high-, intermediate- or low-risk patients; the - concentration of natriuretic peptides is a promising new preoperative risk - marker. beta-blockers considerably reduce this risk. In clinical practice, - important factors are adequate beta-blocker dosage, tight perioperative - heart-rate control and continuation of beta-blockers after discharge. Recently, - statins have emerged as drugs with perioperative cardioprotective properties, but - more randomized clinical trials are needed before routine administration - ofstatins can be recommended. Perioperative medical management should focus on - improvements not only in the short-term but also in the long-term. -FAU - Feringa, H H H -AU - Feringa HH -AD - Afd. Cardiologie, Erasmus MC-Centrum, Dr.Molewaterplein 40, 3015 GD Rotterdam. -FAU - Bax, J J -AU - Bax JJ -FAU - Poldermans, D -AU - Poldermans D -LA - dut -PT - English Abstract -PT - Journal Article -PT - Review -TT - Perioperatieve risicoreductie bij vaatoperaties door cardioprotectieve medicatie. -PL - Netherlands -TA - Ned Tijdschr Geneeskd -JT - Nederlands tijdschrift voor geneeskunde -JID - 0400770 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Cardiotonic Agents) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -CIN - Ned Tijdschr Geneeskd. 2008 Nov 29;152(48):2600-2. PMID: 19102433 -MH - Adrenergic beta-Antagonists/*therapeutic use -MH - Cardiotonic Agents/*therapeutic use -MH - Cardiovascular Diseases/etiology/mortality/*prevention & control -MH - Heart Rate/drug effects -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Patient Care Planning -MH - Perioperative Care/methods/*standards -MH - Risk Assessment -MH - Risk Factors -MH - Surgical Procedures, Operative/*adverse effects -RF - 30 -EDAT- 2008/12/24 09:00 -MHDA- 2009/01/14 09:00 -CRDT- 2008/12/24 09:00 -PHST- 2008/12/24 09:00 [entrez] -PHST- 2008/12/24 09:00 [pubmed] -PHST- 2009/01/14 09:00 [medline] -PST - ppublish -SO - Ned Tijdschr Geneeskd. 2008 Nov 29;152(48):2606-11. - -PMID- 17019813 -OWN - NLM -STAT- MEDLINE -DCOM- 20070112 -LR - 20250529 -IS - 1528-2511 (Print) -IS - 1528-2511 (Linking) -VI - 274 -DP - 2006 -TI - The cardiomyocyte cell cycle. -PG - 196-207; discussion 208-13, 272-6 -AB - Many forms of cardiac disease are characterized by cardiomyocyte death due to - necrosis, apoptosis and/or oncosis. Recently, the notion of promoting cardiac - regeneration as a means to replace damaged heart tissue has engendered - considerable interest. One approach to accomplish heart muscle regeneration - entails promoting cardiomyocyte cell cycle activity in the surviving myocardium. - Genetically modified mice have provided useful model systems to test the efficacy - of specific pathways to promote cardiomyocyte proliferation in normal and - diseased hearts. For example, expression of a heart-restricted dominant - interfering version of p193 (an E3 ubiquitin ligase also known as Cul7) resulted - in an induction of cardiomyocyte cell cycle activity at the infarct border zone - and ventricular septum 4 weeks after permanent coronary artery occlusion. A - concomitant reduction in hypertrophic cardiomyocyte growth was also observed in - this model, suggesting that cell cycle activation partially counteracted the - adverse ventricular remodelling that occurs post-infarction. In other studies, - targeted expression of cyclin D2 promoted cardiomyocyte cell cycle activity in - adult hearts. The level of cardiomyocyte cell cycle activity increased after - myocardial infarction, ultimately resulting in a marked increase in cardiomyocyte - number and a concomitant regression of infarct size. Collectively, these data - suggest that modulation of cardiomyocyte cell cycle activity can be exploited to - promote regenerative growth in injured hearts. -FAU - Lafontant, Pascal J E -AU - Lafontant PJ -AD - Wells Center for Pediatric Research and Krannert Institute of Cardiology, Indiana - University School of Medicine, Indianapolis, IN 46202-5225, USA. -FAU - Field, Loren J -AU - Field LJ -LA - eng -GR - P01 HL085098/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Review -PL - England -TA - Novartis Found Symp -JT - Novartis Foundation symposium -JID - 9807767 -RN - 0 (CCND2 protein, human) -RN - 0 (Cyclin D2) -RN - 0 (Cyclins) -RN - 9007-49-2 (DNA) -SB - IM -MH - Animals -MH - Apoptosis -MH - Cardiovascular Diseases/metabolism/pathology -MH - *Cell Cycle -MH - Cyclin D2 -MH - Cyclins/genetics -MH - DNA/metabolism -MH - Genes, Dominant -MH - Humans -MH - Models, Biological -MH - Myocytes, Cardiac/*cytology/*pathology -MH - Time Factors -MH - Transgenes -MH - Ventricular Remodeling -PMC - PMC2628757 -MID - NIHMS57480 -EDAT- 2006/10/06 09:00 -MHDA- 2007/01/16 09:00 -PMCR- 2009/01/20 -CRDT- 2006/10/06 09:00 -PHST- 2006/10/06 09:00 [pubmed] -PHST- 2007/01/16 09:00 [medline] -PHST- 2006/10/06 09:00 [entrez] -PHST- 2009/01/20 00:00 [pmc-release] -AID - 10.1002/0470029331.ch12 [doi] -PST - ppublish -SO - Novartis Found Symp. 2006;274:196-207; discussion 208-13, 272-6. doi: - 10.1002/0470029331.ch12. - -PMID- 17149675 -OWN - NLM -STAT- MEDLINE -DCOM- 20070516 -LR - 20151119 -IS - 0340-9937 (Print) -IS - 0340-9937 (Linking) -VI - 31 -IP - 8 -DP - 2006 Nov -TI - [Acute heart failure: rational diagnostics in clinical practice and the emergency - department]. -PG - 736-47 -AB - Despite being as common as an acute myocardial infarction in the emergency - department, the diagnostic criteria and the therapeutic guidelines for heart - failure treatment are much less well defined. Thanks to the recently published - guidelines of the European Society of Cardiology (ESC) the diagnosis of acute - heart failure syndromes (AHFS) is now better standardized. The ESC distinguishes - between six AHFS: (I) acute decompensated chronic heart failure, (II) acute heart - failure with hypertension/hypertensive crisis, (III) acute heart failure with - pulmonary edema, (IV) cardiogenic shock, (V) high-output failure, and (VI) - right-sided acute heart failure. To distinguish between these entities in a - clinical setting, a well-structured clinical examination is of paramount - importance. Signs of peripheral hypoperfusion and congestion/fluid overload need - to be recognized rapidly. These two clinical parameters permit the assessment of - the patient based on the Clinical Severity Classification. Further diagnostic - work-up should include chest X-ray, echocardiography, clinical chemistry, and - blood gas analysis. The invasive coronary angiography is only beneficial in the - context of an acute ST elevation myocardial infarction or NSTEMIs with persistent - symptoms of angina. In all other cases cardiac catheterization should be deferred - until the patient is recompensated. Diagnostic algorithms help to maintain a high - standard in clinical diagnosis and improve the safety and efficacy of subsequent - therapeutic interventions. -FAU - Gielen, Stephan -AU - Gielen S -AD - Klinik für Innere Medizin/Kardiologie, Universität Leipzig, Herzzentrum GmbH, - Leipzig. -FAU - Sandri, Marcus -AU - Sandri M -FAU - Schuler, Gerhard C -AU - Schuler GC -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Akute Herzinsuffizienz: rationale Diagnostik in der Praxis und der Notaufnahme. -PL - Germany -TA - Herz -JT - Herz -JID - 7801231 -SB - IM -MH - Acute Disease -MH - Cardiac Output, Low/*classification/*diagnosis -MH - *Decision Support Systems, Clinical -MH - Diagnosis, Differential -MH - Emergency Medical Services/*methods/standards -MH - Emergency Medicine/methods/standards -MH - Germany -MH - Humans -MH - *Practice Guidelines as Topic -MH - Practice Patterns, Physicians'/standards -RF - 48 -EDAT- 2006/12/07 09:00 -MHDA- 2007/05/17 09:00 -CRDT- 2006/12/07 09:00 -PHST- 2006/12/07 09:00 [pubmed] -PHST- 2007/05/17 09:00 [medline] -PHST- 2006/12/07 09:00 [entrez] -AID - 10.1007/s00059-006-2916-5 [doi] -PST - ppublish -SO - Herz. 2006 Nov;31(8):736-47. doi: 10.1007/s00059-006-2916-5. - -PMID- 18612782 -OWN - NLM -STAT- MEDLINE -DCOM- 20081203 -LR - 20211020 -IS - 0941-1291 (Print) -IS - 0941-1291 (Linking) -VI - 38 -IP - 7 -DP - 2008 -TI - Simultaneous open-heart surgery and pectus deformity correction. -PG - 592-6 -LID - 10.1007/s00595-007-3692-4 [doi] -AB - PURPOSE: Pectus deformities and cardiac problems sometimes require simultaneous - surgery. We report our experience of performing this surgery and review the - relevant literature. METHODS: We performed simultaneous pectus deformity - correction and open-heart surgery in six patients between 1999 and 2006. The - pectus deformities were pectus carinatum in one patient and pectus excavatum in - five patients. The cardiac problems were coronary artery disease in one patient, - an atrioseptal defect (ASD) with a ventricular septal defect (VSD) in one, a VSD - in one, mitral valve insufficiency with left atrial dilatation in one, and an - ascending aortic aneurysm with aortic valve insufficiency caused by Marfan's - syndrome in two. We corrected the pectus deformities using the modified Ravitch's - sternoplasty in all patients. First, while the patient was supine, we resected - the costal cartilage; then, after completing the cardiac surgery, the sternum was - closed and the additional time required for the pectus operation was calculated - for each patient. Patients were examined 1, 4, and 6 months postoperatively. - RESULTS: The average operation time was 102 min, and there were no major - complications. The pectus bars were removed 4-6 months postoperatively. Good - cardiac and cosmetic results were achieved in all patients, who were followed up - for 5 years. CONCLUSIONS: Concomitant pectus deformity correction and open-heart - surgery can be performed safely, eliminating the risks of a second operation in a - staged procedure. -FAU - Okay, Tamer -AU - Okay T -AD - Dr Siyami Ersek Thoracic and Cardiovascular Surgery, Training and Research - Hospital, Istanbul, Turkey. -FAU - Ketenci, Bulend -AU - Ketenci B -FAU - Imamoglu, Oya Uncu -AU - Imamoglu OU -FAU - Aydemir, Bulent -AU - Aydemir B -FAU - Tuygun, Abdullah Kemal -AU - Tuygun AK -FAU - Ozay, Batuhan -AU - Ozay B -FAU - Yapici, Fikri -AU - Yapici F -FAU - Coruh, Turkan Kutsioglu -AU - Coruh TK -FAU - Demirtas, Mahmut Murat -AU - Demirtas MM -LA - eng -PT - Journal Article -PT - Review -DEP - 20080709 -PL - Japan -TA - Surg Today -JT - Surgery today -JID - 9204360 -SB - IM -MH - Adult -MH - Child -MH - Female -MH - Follow-Up Studies -MH - Funnel Chest/complications/*surgery -MH - Heart Diseases/complications/*surgery -MH - Humans -MH - Length of Stay -MH - Male -MH - Middle Aged -MH - *Postoperative Complications -MH - Respiration, Artificial/statistics & numerical data -MH - Sternum/surgery -MH - Thoracic Surgical Procedures/methods -MH - Treatment Outcome -RF - 13 -EDAT- 2008/07/10 09:00 -MHDA- 2008/12/17 09:00 -CRDT- 2008/07/10 09:00 -PHST- 2007/02/05 00:00 [received] -PHST- 2007/08/27 00:00 [accepted] -PHST- 2008/07/10 09:00 [pubmed] -PHST- 2008/12/17 09:00 [medline] -PHST- 2008/07/10 09:00 [entrez] -AID - 10.1007/s00595-007-3692-4 [doi] -PST - ppublish -SO - Surg Today. 2008;38(7):592-6. doi: 10.1007/s00595-007-3692-4. Epub 2008 Jul 9. - -PMID- 20875159 -OWN - NLM -STAT- MEDLINE -DCOM- 20101230 -LR - 20250529 -IS - 0020-1324 (Print) -IS - 0020-1324 (Linking) -VI - 55 -IP - 10 -DP - 2010 Oct -TI - Sleep-disordered breathing and cardiovascular disorders. -PG - 1322-32; discussion 1330-2 -AB - Compelling data demonstrate a strong association between sleep-disordered - breathing (SDB) and cardiovascular disorders. The association is most consistent - between obstructive sleep apnea (OSA) and hypertension. Epidemiologic and - clinic-based studies provide evidence for an etiological role of OSA in - hypertension, independent of obesity. Furthermore, several studies suggest - amelioration of hypertension with therapy for sleep apnea. Emerging data also - suggest a role for OSA in causing coronary artery disease. This association is - bolstered by evidence suggesting that continuous positive airway pressure (CPAP) - therapy improves early signs of atherosclerosis and may impede progression to - clinically important cardiovascular disease. SDB (both OSA and central sleep - apnea) is frequently observed in patients with heart failure. OSA may be a risk - factor for incident heart failure. The current data do not provide consistent - evidence for whether treatment of SDB will improve survival or other end points - in patients with heart failure, and larger trials are currently underway to - better elucidate that relationship. Substantial evidence also links SDB to an - increased risk of various arrhythmias. Treatment of SDB with CPAP appears to - significantly attenuate that risk. Finally, several studies suggest SDB as a risk - factor for stroke. Whether treatment of SDB reduces stroke risk, however, remains - to be determined. In conclusion, persuasive data provide evidence for an - association, probably causal, between sleep-disordered breathing and several - cardiovascular disorders. Large randomized controlled trials will further help - confirm the association and elucidate the cardiovascular benefits of SDB therapy. -FAU - Budhiraja, Rohit -AU - Budhiraja R -AD - Division of Sleep Medicine, Harvard Medical School and Brigham and Women's - Hospital, Boston, MA 02215, USA. -FAU - Budhiraja, Pooja -AU - Budhiraja P -FAU - Quan, Stuart F -AU - Quan SF -LA - eng -GR - U01 HL053938/HL/NHLBI NIH HHS/United States -GR - HL068060/HL/NHLBI NIH HHS/United States -GR - HL53938/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Respir Care -JT - Respiratory care -JID - 7510357 -SB - IM -MH - Cardiovascular Diseases/etiology/*prevention & control -MH - *Continuous Positive Airway Pressure -MH - Humans -MH - Risk Reduction Behavior -MH - Sleep Apnea Syndromes/complications/*therapy -PMC - PMC2972194 -MID - NIHMS244911 -EDAT- 2010/09/30 06:00 -MHDA- 2010/12/31 06:00 -PMCR- 2010/11/03 -CRDT- 2010/09/30 06:00 -PHST- 2010/09/30 06:00 [entrez] -PHST- 2010/09/30 06:00 [pubmed] -PHST- 2010/12/31 06:00 [medline] -PHST- 2010/11/03 00:00 [pmc-release] -PST - ppublish -SO - Respir Care. 2010 Oct;55(10):1322-32; discussion 1330-2. - -PMID- 22607214 -OWN - NLM -STAT- MEDLINE -DCOM- 20121127 -LR - 20241105 -IS - 1525-139X (Electronic) -IS - 0894-0959 (Linking) -VI - 25 -IP - 3 -DP - 2012 May -TI - Clinical utility of natriuretic peptides in dialysis patients. -PG - 326-33 -LID - 10.1111/j.1525-139X.2012.01079.x [doi] -AB - Dialysis patients suffer a greatly heightened risk of cardiovascular morbidity - and mortality. These patients also experience an extremely high prevalence of - left ventricular hypertrophy, heart failure, and coronary artery disease. Thus, - there is a clinical need to identify circulating biomarkers that have diagnostic - value for cardiovascular disease and have prognostic importance so to facilitate - earlier and more aggressive intervention. The natriuretic peptides, namely brain - natriuretic peptide (BNP) or N-terminal pro-brain natriuretic peptide - (NT-pro-BNP), belong to a family of vasopeptide hormones that are released from - the heart and play a major role in blood pressure regulation and volume - homeostasis through their direct effects on the kidney and systemic vasculature - and represent a favorable aspect of neurohumoral activation. Testing for BNP or - NT-pro-BNP has recently emerged as important diagnostic tool for heart failure - and a useful biomarker for risk stratification in the general population. In - dialysis patients, there has been interest in evaluating the potential of BNP and - NT-pro-BNP as markers of volume status as they are frequently elevated in - dialysis patients. However, the interpretation of their levels is confounded by - impaired renal clearance and preexisting LV abnormalities which have limited - their applicability as a surrogate marker of volume status. In this article, we - discuss the pathophysiology accounting for the elevation of natriuretic peptides - in dialysis patients and review current evidence that supports their clinical - utility as a diagnostic and prognostic tool in this population. -CI - © 2012 Wiley Periodicals, Inc. -FAU - Wang, Angela Yee-Moon -AU - Wang AY -AD - Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong. - aymwang@hku.hk -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Semin Dial -JT - Seminars in dialysis -JID - 8911629 -RN - 0 (Biomarkers) -RN - 0 (Natriuretic Peptides) -SB - IM -MH - Biomarkers/blood -MH - *Cardiovascular Diseases/blood/epidemiology/etiology -MH - Global Health -MH - Humans -MH - Incidence -MH - Kidney Failure, Chronic/blood/complications/*therapy -MH - Natriuretic Peptides/*blood -MH - *Renal Dialysis -MH - Risk Factors -EDAT- 2012/05/23 06:00 -MHDA- 2012/12/10 06:00 -CRDT- 2012/05/22 06:00 -PHST- 2012/05/22 06:00 [entrez] -PHST- 2012/05/23 06:00 [pubmed] -PHST- 2012/12/10 06:00 [medline] -AID - 10.1111/j.1525-139X.2012.01079.x [doi] -PST - ppublish -SO - Semin Dial. 2012 May;25(3):326-33. doi: 10.1111/j.1525-139X.2012.01079.x. - -PMID- 16979427 -OWN - NLM -STAT- MEDLINE -DCOM- 20061102 -LR - 20151119 -IS - 0026-0495 (Print) -IS - 0026-0495 (Linking) -VI - 55 -IP - 10 Suppl 2 -DP - 2006 Oct -TI - Sleep and vascular disorders. -PG - S45-9 -AB - It is not surprising that cardiovascular diseases such as congestive heart - failure and coronary insufficiency can give rise to varying degrees of sleep - impairment; it is less readily appreciated that certain physiologic events - occurring during sleep-as well as long-term unsatisfactory sleep-may cause or - increase the risk of cardiovascular conditions such as hypertension, - atherosclerosis, stroke, and cardiac arrythmias. Heart rate abnormalities during - sleep in normotensive subjects predict later cardiovascular disease, and their - early identification alerts the physician to undertake preventive measures. - Maneuvers, such as induction of hypoxia, can elicit abnormal blood pressure - responses during sleep, and such responses have been used to identify impending - cardiovascular problems that could become therapeutic targets. The spontaneously - hypertensive rat has been used to examine the effect of sympathetic nervous - system (SNS) activity on the heart under a variety of experimental conditions, - including quiet and paradoxical sleep. The results have disclosed significant - differences between the responses of spontaneously hypertensive rats and normal - rats to SNS stimulation. Exploration of other pathophysiologic pathways affected - by exposure to light and dark, including those responsive to the cyclic - production of melatonin, will improve our understanding of the effect of - disruptions of the circadian cycle on cardiovascular function. There is growing - evidence that melatonin can influence important processes such as fluid, - nitrogen, and acid-base balance. Human subjects whose nocturnal arterial blood - pressure fails to show the "normal" decrement during sleep ("nondippers") are - also prone to sleep poorly, exhibit increased SNS activity during sleep, and have - an increased risk of total and cardiovascular disease mortality. Chronic sleep - deficit is now known to be a risk factor for obesity and may contribute to the - visceral form of obesity that underlies the metabolic syndrome. The rising - prevalence of obstructive sleep apnea and central sleep apnea is linked to the - modern-day epidemic of obesity. Obstructive sleep apnea is associated with an - enhanced risk of having a new stroke or a transient ischemic attack. -FAU - Plante, Gérard E -AU - Plante GE -AD - Department of Medicine (Nephrology), Institute of Geriatrics, University of - Sherbrooke, Sherbrook, Québec, Canada JIH 5N4. gerard.plante@usherbrooke.ca -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Metabolism -JT - Metabolism: clinical and experimental -JID - 0375267 -RN - JL5DK93RCL (Melatonin) -SB - IM -MH - Animals -MH - Humans -MH - Melatonin/physiology -MH - Rats -MH - Sleep Wake Disorders/*complications/physiopathology -MH - Sympathetic Nervous System/physiopathology -MH - Vascular Diseases/*etiology/physiopathology -RF - 36 -EDAT- 2006/09/19 09:00 -MHDA- 2006/11/03 09:00 -CRDT- 2006/09/19 09:00 -PHST- 2006/09/19 09:00 [pubmed] -PHST- 2006/11/03 09:00 [medline] -PHST- 2006/09/19 09:00 [entrez] -AID - S0026-0495(06)00233-2 [pii] -AID - 10.1016/j.metabol.2006.07.013 [doi] -PST - ppublish -SO - Metabolism. 2006 Oct;55(10 Suppl 2):S45-9. doi: 10.1016/j.metabol.2006.07.013. - -PMID- 22233315 -OWN - NLM -STAT- MEDLINE -DCOM- 20120221 -LR - 20191112 -IS - 2980-3187 (Electronic) -IS - 0494-1373 (Linking) -VI - 59 -IP - 4 -DP - 2011 -TI - [Cardiovascular biomarkers in clinical practice of sleep apnea]. -PG - 402-8 -AB - Obstructive sleep apnea syndrome (OSAS) leads to cardiovascular complications - such as coronary artery disease, left/right ventricular hypertrophy and - dysfunction, heart failure, systemic and pulmonary hypertension, arrhythmias and - stroke; and these all cardiovascular complications increase morbidity and - mortality of OSAS. However, Cheyne-Stokes respiration, central and obstructive - apneas may occur in the patient with heart failure. Increased sympathetic - activity by hypoxemia and endothelial dysfunction play a role in cardiovascular - complications. Some cardiovascular biomarkers have a role in early diagnosis, - treatment and prognosis. In the present review, some cardiovascular biomarkers - such as serum C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), - interleukins, adiponectin, heart-type fatty acid binding protein (hFABP) and - brain (B-type) natriuretic peptide (BNP), and their clinical importance were - reviewed. -FAU - Dursunoğlu, Dursun -AU - Dursunoğlu D -AD - Department of Cardiology, Faculty of Medicine, Pamukkale University, Denizli, - Turkey. dursundursunoglu@yahoo.com -FAU - Dursunoğlu, Neşe -AU - Dursunoğlu N -LA - tur -PT - English Abstract -PT - Journal Article -PT - Review -TT - Uyku apnesinin klinik uygulamasinda kardiyovasküler biyobelirteçler. -PL - Turkey -TA - Tuberk Toraks -JT - Tuberkuloz ve toraks -JID - 0417364 -RN - 0 (Adiponectin) -RN - 0 (Biomarkers) -RN - 0 (Interleukins) -RN - 0 (Tumor Necrosis Factor-alpha) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - 9007-41-4 (C-Reactive Protein) -SB - IM -MH - Adiponectin/blood -MH - Biomarkers/*blood -MH - C-Reactive Protein/metabolism -MH - Cardiovascular Diseases/*blood/*diagnosis/etiology/prevention & control -MH - Early Diagnosis -MH - Humans -MH - Interleukins/blood -MH - Natriuretic Peptide, Brain/blood -MH - Prognosis -MH - Sleep Apnea, Obstructive/*blood/complications/*diagnosis -MH - Tumor Necrosis Factor-alpha/blood -EDAT- 2012/01/12 06:00 -MHDA- 2012/02/22 06:00 -CRDT- 2012/01/12 06:00 -PHST- 2012/01/12 06:00 [entrez] -PHST- 2012/01/12 06:00 [pubmed] -PHST- 2012/02/22 06:00 [medline] -AID - 10.5578/tt.1448 [doi] -PST - ppublish -SO - Tuberk Toraks. 2011;59(4):402-8. doi: 10.5578/tt.1448. - -PMID- 19952893 -OWN - NLM -STAT- MEDLINE -DCOM- 20110805 -LR - 20250529 -IS - 1708-8267 (Electronic) -IS - 1081-5589 (Print) -IS - 1081-5589 (Linking) -VI - 57 -IP - 8 -DP - 2009 Dec -TI - Integrins, focal adhesions, and cardiac fibroblasts. -PG - 856-60 -LID - 10.2310/JIM.0b013e3181c5e61f [doi] -AB - How the myocardium undergoes geometric, structural, and molecular alterations - that result in an end phenotype as might be seen in patients with dilated - cardiomyopathy or after myocardial infarction is still poorly understood. - Structural modification of the left ventricle, which occurs during these - pathological states, results from long-term changes in loading conditions and is - commonly referred to as "remodeling." Remodeling may occur from increased wall - stress in the face of hypertensive heart disease, valvular disease, or, perhaps - most dramatically, after permanent coronary occlusion. A fundamental derangement - of myocyte function is the most common perception for the basis of remodeling, - but the role of cells in the heart other than the muscle cell must, of course, be - considered. Although studies of the myocyte have been extensive, cardiac - fibroblasts have been studied less than myocytes. The fibroblast has a broad - range of functions in the myocardium ranging from elaboration and remodeling of - the extracellular matrix to communication of a range of signals within the heart, - including electrical, chemical, and mechanical ones. Integrins are cell surface - receptors that are instrumental in mediating cell-matrix interactions in all - cells of the organism, including all types within the myocardium. This review - will focus on the role of integrins and related proteins in the remodeling - process, with a particular emphasis on the cardiac fibroblast. We will illustrate - this function by drawing on 2 unique mouse models with perturbation of proteins - linked to integrin function. -FAU - Manso, Ana Maria -AU - Manso AM -AD - Department of Medicine, UCSD School of Medicine, La Jolla, CA, USA. -FAU - Kang, Seok-Min -AU - Kang SM -FAU - Ross, Robert S -AU - Ross RS -LA - eng -GR - R01 HL088390/HL/NHLBI NIH HHS/United States -GR - P01 HL066941/HL/NHLBI NIH HHS/United States -GR - P01 HL046345/HL/NHLBI NIH HHS/United States -GR - T32 HL007444/HL/NHLBI NIH HHS/United States -GR - R13 RR023236/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - England -TA - J Investig Med -JT - Journal of investigative medicine : the official publication of the American - Federation for Clinical Research -JID - 9501229 -RN - 0 (Integrins) -SB - IM -MH - Animals -MH - Fibroblasts/pathology/*physiology -MH - Focal Adhesions/genetics/*metabolism/pathology -MH - Humans -MH - Integrins/genetics/*physiology -MH - Myocytes, Cardiac/pathology/*physiology -PMC - PMC2810503 -MID - NIHMS166964 -EDAT- 2009/12/03 06:00 -MHDA- 2011/08/06 06:00 -PMCR- 2010/12/01 -CRDT- 2009/12/03 06:00 -PHST- 2009/12/03 06:00 [entrez] -PHST- 2009/12/03 06:00 [pubmed] -PHST- 2011/08/06 06:00 [medline] -PHST- 2010/12/01 00:00 [pmc-release] -AID - 00042871-200912000-00010 [pii] -AID - 10.2310/JIM.0b013e3181c5e61f [doi] -PST - ppublish -SO - J Investig Med. 2009 Dec;57(8):856-60. doi: 10.2310/JIM.0b013e3181c5e61f. - -PMID- 18091134 -OWN - NLM -STAT- MEDLINE -DCOM- 20080306 -LR - 20220318 -IS - 1741-8267 (Print) -IS - 1741-8267 (Linking) -VI - 14 Suppl 3 -DP - 2007 Dec -TI - Population-based register of acute myocardial infarction: manual of operations. -PG - S3-22 -LID - 10.1097/01.hjr.0000277986.33343.94 [doi] -AB - Cardiovascular disease is the leading cause of death and hospitalization in both - sexes in nearly all countries of Europe. The main forms of cardiovascular disease - are ischaemic heart disease and stroke. The magnitude of the problem contrasts - with the shortage, weak quality and comparability of data available in most - European countries. Innovations in medical, invasive and biological treatments - have substantially contributed to the escalating costs of health services. It is - therefore urgent to obtain reliable information on the magnitude and distribution - of the disease for both adequate health planning (including preventive - strategies) and clinical decision making with correct cost-benefit assessments.A - stepwise surveillance procedure based on standardized data collection, - appropriate record linkage and validation methods was set up by the EUROCISS - Project (EUROpean Cardiovascular Indicators Surveillance Set) to build up - comparable and reliable indicators (attack rate and case fatality) for the - surveillance of acute myocardial infarction/acute coronary syndrome at population - level. This manual of operations is intended for health professionals and policy - makers and provides a standardized and simple model for the implementation of a - population-based register. It recommends to start from a minimum data set and - then follow a stepwise procedure. Before implementing a population-based - register, it is important to identify the target population under surveillance - which should preferably cover a well-defined geographical and administrative area - or region representative of the whole country for which population data and vital - statistics (mortality and hospital discharge records at minimum) are routinely - collected and easily available each year. All cases among residents should be - recorded even if the case occurs outside the area. Validation of a sample of - fatal and nonfatal events is mandatory. -FAU - Madsen, Mette -AU - Madsen M -AD - Institute of Public Health, University of Copenhagen, Copenhagen, Denmark. -FAU - Gudnason, Vilmundur -AU - Gudnason V -FAU - Pajak, Andrzej -AU - Pajak A -FAU - Palmieri, Luigi -AU - Palmieri L -FAU - Rocha, Evangelista C -AU - Rocha EC -FAU - Salomaa, Veikko -AU - Salomaa V -FAU - Sans, Susana -AU - Sans S -FAU - Steinbach, Konrad -AU - Steinbach K -FAU - Vanuzzo, Diego -AU - Vanuzzo D -CN - EUROCISS Research Group -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Eur J Cardiovasc Prev Rehabil -JT - European journal of cardiovascular prevention and rehabilitation : official - journal of the European Society of Cardiology, Working Groups on Epidemiology & - Prevention and Cardiac Rehabilitation and Exercise Physiology -JID - 101192000 -SB - IM -MH - Europe/epidemiology -MH - *Health Status Indicators -MH - Humans -MH - Incidence -MH - *Manuals as Topic -MH - Myocardial Infarction/classification/*epidemiology -MH - Population Surveillance/*methods -MH - Public Health Informatics -MH - *Registries -RF - 32 -EDAT- 2008/02/07 09:00 -MHDA- 2008/03/07 09:00 -CRDT- 2008/02/07 09:00 -PHST- 2008/02/07 09:00 [pubmed] -PHST- 2008/03/07 09:00 [medline] -PHST- 2008/02/07 09:00 [entrez] -AID - 00149831-200712001-00002 [pii] -AID - 10.1097/01.hjr.0000277986.33343.94 [doi] -PST - ppublish -SO - Eur J Cardiovasc Prev Rehabil. 2007 Dec;14 Suppl 3:S3-22. doi: - 10.1097/01.hjr.0000277986.33343.94. - -PMID- 17041765 -OWN - NLM -STAT- MEDLINE -DCOM- 20070123 -LR - 20181113 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 11 -IP - 3 -DP - 2006 Sep -TI - New techniques for percutaneous repair of the mitral valve. -PG - 259-68 -AB - A variety of innovative techniques and devices are being developed for the - percutaneous management of mitral insufficiency. More than 30 devices are in - stages of development from early stage to human pivotal trials. Two devices for - the management of degenerative myxomatous disease of the mitral valve replicate - the Alfieri edge-to-edge surgical repair. One of those devices, the Evalve - Mitraclip, is in a pivotal trial at the current time. The other devices address - functional mitral regurgitation by a variety of techniques for performing mitral - valve annuloplasty. The majority of devices take advantage of the proximity of - the coronary sinus to the posterior mitral annulus to deliver devices that - remodel the mitral annulus. Two devices perform septal lateral cinching - decreasing the anterior posterior diameter of the mitral annulus and correcting - leaflet malcoaptation. Numerous issues are discussed including regulatory hurdles - and the integration of percutaneous techniques into clinical practice in a safe - and efficacious manner. -FAU - Mack, Michael J -AU - Mack MJ -AD - Medical City Hospital, Dallas, Texas 75230, USA. slhill@csant.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -SB - IM -MH - Catheterization/*methods -MH - Clinical Trials as Topic -MH - Humans -MH - Mitral Valve Insufficiency/classification/*therapy -RF - 22 -EDAT- 2006/10/17 09:00 -MHDA- 2007/01/24 09:00 -CRDT- 2006/10/17 09:00 -PHST- 2006/10/17 09:00 [pubmed] -PHST- 2007/01/24 09:00 [medline] -PHST- 2006/10/17 09:00 [entrez] -AID - 10.1007/s10741-006-0104-6 [doi] -PST - ppublish -SO - Heart Fail Rev. 2006 Sep;11(3):259-68. doi: 10.1007/s10741-006-0104-6. - -PMID- 17266543 -OWN - NLM -STAT- MEDLINE -DCOM- 20070221 -LR - 20191110 -IS - 1871-5257 (Print) -IS - 1871-5257 (Linking) -VI - 5 -IP - 1 -DP - 2007 Jan -TI - Putative role for apelin in pressure/volume homeostasis and cardiovascular - disease. -PG - 1-10 -AB - Apelin is a peptide recently isolated from bovine stomach extracts which appears - to act as an endogenous ligand for the previously orphaned G-protein-coupled APJ - receptor. The apelin gene encodes for a pre-propeptide consisting of 77 amino - acids with mature apelin likely to be derived from the C-terminal region as - either a 36, 17 or 13 amino acid peptide. Apelin mRNA expression and peptide - immunoreactivity has been described in a variety of tissues including - gastrointestinal tract, adipose tissue, brain, kidney, liver, lung and at various - sites within the cardiovascular system. Apelin is strongly expressed in the heart - with expression also present in the large conduit vessels, coronary vessels and - endothelial cells. Message expression for the APJ receptor is similarly - distributed throughout the brain and periphery, again including cardiovascular - tissue. Consistent with this pattern of distribution, apelin and APJ have been - shown to exhibit some role in the regulation of fluid homeostasis. In addition, a - growing number of studies have reported cardiovascular actions of apelin. Not - only has apelin been observed to alter arterial pressure, but the peptide also - exhibits endothelium-dependent vasodilator actions in vivo and positive inotropic - actions in the isolated heart. Furthermore, differences in apelin and APJ - expression have been described in patients with congestive heart failure and - circulating levels of apelin are also reported to change in heart failure. Taken - together, these studies suggest a role for apelin in pressure/volume homeostasis - and in the pathophysiology of cardiovascular disease. As such, manipulation of - this peptide system may offer benefit to the syndrome of heart failure with - potential clinical applications in humans. -FAU - Charles, Christopher J -AU - Charles CJ -AD - Christchurch Cardioendocrine Research Group, Christchurch School of Medicine and - Health Sciences, PO Box 4345, Christchurch, New Zealand. - chris.charles@chmeds.ac.nz -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiovasc Hematol Agents Med Chem -JT - Cardiovascular & hematological agents in medicinal chemistry -JID - 101266881 -RN - 0 (APLN protein, human) -RN - 0 (APLNR protein, human) -RN - 0 (Apelin) -RN - 0 (Apelin Receptors) -RN - 0 (Intercellular Signaling Peptides and Proteins) -RN - 0 (Receptors, G-Protein-Coupled) -SB - IM -MH - Amino Acid Sequence -MH - Animals -MH - Apelin -MH - Apelin Receptors -MH - *Blood Pressure -MH - Cardiovascular Diseases/drug therapy/*etiology -MH - *Homeostasis -MH - Humans -MH - Intercellular Signaling Peptides and Proteins/chemistry/*physiology/therapeutic - use -MH - Molecular Sequence Data -MH - Receptors, G-Protein-Coupled/physiology -MH - *Water-Electrolyte Balance -RF - 40 -EDAT- 2007/02/03 09:00 -MHDA- 2007/02/22 09:00 -CRDT- 2007/02/03 09:00 -PHST- 2007/02/03 09:00 [pubmed] -PHST- 2007/02/22 09:00 [medline] -PHST- 2007/02/03 09:00 [entrez] -AID - 10.2174/187152507779315804 [doi] -PST - ppublish -SO - Cardiovasc Hematol Agents Med Chem. 2007 Jan;5(1):1-10. doi: - 10.2174/187152507779315804. - -PMID- 19168026 -OWN - NLM -STAT- MEDLINE -DCOM- 20091022 -LR - 20250529 -IS - 0006-3002 (Print) -IS - 0006-3002 (Linking) -VI - 1787 -IP - 11 -DP - 2009 Nov -TI - The role of the mitochondrial permeability transition pore in heart disease. -PG - 1402-15 -LID - 10.1016/j.bbabio.2008.12.017 [doi] -AB - Like Dr. Jeckyll and Mr. Hyde, mitochondria possess two distinct persona. Under - normal physiological conditions they synthesise ATP to meet the energy needs of - the beating heart. Here calcium acts as a signal to balance the rate of ATP - production with ATP demand. However, when the heart is overloaded with calcium, - especially when this is accompanied by oxidative stress, mitochondria embrace - their darker side, and induce necrotic cell death of the myocytes. This happens - acutely in reperfusion injury and chronically in congestive heart failure. Here - calcium overload, adenine nucleotide depletion and oxidative stress combine - forces to induce the opening of a non-specific pore in the mitochondrial - membrane, known as the mitochondrial permeability transition pore (mPTP). The - molecular nature of the mPTP remains controversial but current evidence - implicates a matrix protein, cyclophilin-D (CyP-D) and two inner membrane - proteins, the adenine nucleotide translocase (ANT) and the phosphate carrier - (PiC). Inhibition of mPTP opening can be achieved with inhibitors of each - component, but targeting CyP-D with cyclosporin A (CsA) and its - non-immunosuppressive analogues is the best described. In animal models, - inhibition of mPTP opening by either CsA or genetic ablation of CyP-D provides - strong protection from both reperfusion injury and congestive heart failure. This - confirms the mPTP as a promising drug target in human cardiovascular disease. - Indeed, the first clinical trials have shown CsA treatment improves recovery - after treatment of a coronary thrombosis with angioplasty. -FAU - Halestrap, Andrew P -AU - Halestrap AP -AD - Department of Biochemistry and Bristol Heart Institute, University of Bristol, - School of Medical Sciences, University Walk, Bristol BS8 1TD, UK. - A.Halestrap@Bristol.ac.uk -FAU - Pasdois, Philippe -AU - Pasdois P -LA - eng -GR - RG/08/001/24717/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090108 -PL - Netherlands -TA - Biochim Biophys Acta -JT - Biochimica et biophysica acta -JID - 0217513 -RN - 0 (Peptidyl-Prolyl Isomerase F) -RN - 0 (Mitochondrial Membrane Transport Proteins) -RN - 0 (Mitochondrial Permeability Transition Pore) -RN - 9068-80-8 (Mitochondrial ADP, ATP Translocases) -RN - EC 5.2.1.- (Cyclophilins) -SB - IM -MH - Animals -MH - Cardiomegaly/prevention & control -MH - Peptidyl-Prolyl Isomerase F -MH - Cyclophilins/antagonists & inhibitors/physiology -MH - Heart Diseases/*etiology -MH - Heart Failure/etiology -MH - Humans -MH - Ischemic Preconditioning, Myocardial -MH - Mitochondrial ADP, ATP Translocases/physiology -MH - Mitochondrial Membrane Transport Proteins/drug effects/*physiology -MH - Mitochondrial Permeability Transition Pore -MH - Myocardial Reperfusion Injury/etiology/prevention & control -RF - 226 -EDAT- 2009/01/27 09:00 -MHDA- 2009/10/23 06:00 -CRDT- 2009/01/27 09:00 -PHST- 2008/10/22 00:00 [received] -PHST- 2008/12/19 00:00 [revised] -PHST- 2008/12/20 00:00 [accepted] -PHST- 2009/01/27 09:00 [entrez] -PHST- 2009/01/27 09:00 [pubmed] -PHST- 2009/10/23 06:00 [medline] -AID - S0005-2728(09)00007-3 [pii] -AID - 10.1016/j.bbabio.2008.12.017 [doi] -PST - ppublish -SO - Biochim Biophys Acta. 2009 Nov;1787(11):1402-15. doi: - 10.1016/j.bbabio.2008.12.017. Epub 2009 Jan 8. - -PMID- 20418270 -OWN - NLM -STAT- MEDLINE -DCOM- 20100909 -LR - 20181201 -IS - 1753-9455 (Electronic) -IS - 1753-9447 (Linking) -VI - 4 -IP - 3 -DP - 2010 Jun -TI - Dronedarone: an emerging therapy for atrial fibrillation. -PG - 155-64 -LID - 10.1177/1753944710366266 [doi] -AB - Atrial fibrillation (AF) is a common arrhythmia, with a prevalence ranging from - 0.1% to 9.0% at different ages, and is associated with increased cardiovascular - events and mortality. A significant increase in the prevalence of the disease is - expected to occur in the coming years as a consequence of the aging of the - population and advances in the management of coronary artery disease and heart - failure. Effective rhythm control may be difficult to obtain in a significant - proportion of patients with AF. The limited efficacy and the possible adverse - effects of antiarrhythmic drugs has led researchers to focus their attention on - new molecules, in a search of compounds with antiarrhythmic efficacy and a more - favourable safety profile. Among several new drugs developed for the management - of AF, dronedarone, a benzofuran derivative that shares many of the - antiarrhythmic properties of amiodarone, but with a more favourable safety - profile, seems particularly promising. The drug is noniodinated, has less - lipophilicity, reaches therapeutic concentrations over a shorter period of time - and has lower tissue accumulation. Dronedarone, similarly to amiodarone, exhibits - electrophysiologic characteristics of all 4 Vaughan Williams classes. Clinical - studies have shown that dronedarone effectively reduces ventricular rate, may - prevent or delay the recurrence of AF, and may reduce cardiovascular morbidity - and mortality in patients with AF or atrial flutter. The drug has an overall good - safety profile, in particular with low pulmonary and thyroid toxicity. An - important exception is represented by patients with unstable haemodynamic - conditions, in which the use of dronedarone has been found to be associated with - an increase in mortality. Dronedarone has been recently approved for clinical use - by the Food and Drug Administration and by the European Medicines Agency. Further - results from trials and clinical use will better define the efficacy and safety - profile of dronedarone in AF compared with other antiarrhythmic drugs and its - role in the management of patients with AF. -FAU - Rosei, Enrico Agabiti -AU - Rosei EA -AD - Internal Medicine University of Brescia, c/o 2a Medicina Spedali Civili di - Brescia, Piazzale Spedali Civili 1,1, 25123 Brescia, Italy. agabiti@med.unibs.it -FAU - Salvetti, Massimo -AU - Salvetti M -LA - eng -PT - Journal Article -PT - Review -DEP - 20100423 -PL - England -TA - Ther Adv Cardiovasc Dis -JT - Therapeutic advances in cardiovascular disease -JID - 101316343 -RN - 0 (Anti-Arrhythmia Agents) -RN - JQZ1L091Y2 (Dronedarone) -RN - N3RQ532IUT (Amiodarone) -SB - IM -MH - Amiodarone/adverse effects/*analogs & derivatives/therapeutic use -MH - Animals -MH - Anti-Arrhythmia Agents/adverse effects/*therapeutic use -MH - Atrial Fibrillation/*drug therapy/physiopathology -MH - Dronedarone -MH - Drug Approval -MH - Heart Rate/drug effects -MH - Heart Ventricles/physiopathology -MH - Humans -MH - Secondary Prevention -MH - Treatment Outcome -RF - 31 -EDAT- 2010/04/27 06:00 -MHDA- 2010/09/10 06:00 -CRDT- 2010/04/27 06:00 -PHST- 2010/04/27 06:00 [entrez] -PHST- 2010/04/27 06:00 [pubmed] -PHST- 2010/09/10 06:00 [medline] -AID - 1753944710366266 [pii] -AID - 10.1177/1753944710366266 [doi] -PST - ppublish -SO - Ther Adv Cardiovasc Dis. 2010 Jun;4(3):155-64. doi: 10.1177/1753944710366266. - Epub 2010 Apr 23. - -PMID- 22890038 -OWN - NLM -STAT- MEDLINE -DCOM- 20130426 -LR - 20181201 -IS - 1531-7013 (Electronic) -IS - 1087-2418 (Linking) -VI - 17 -IP - 5 -DP - 2012 Oct -TI - Antibody-mediated rejection. -PG - 551-7 -LID - 10.1097/MOT.0b013e3283577fef [doi] -AB - PURPOSE OF REVIEW: The diagnosis of antibody-mediated rejection (AMR) has been - revolutionized in recent years by advances in the detection of human leukocyte - antigen (HLA) and non-HLA antibodies and by the standardized classification of - histologic and immunologic changes in endomyocardial biopsies. The treatment of - AMR is also undergoing significant development with targeted use of therapies - directed at antibody production and function. RECENT FINDINGS: The diagnosis of - AMR achieved greater standardization after a consensus conference in 2010. By the - proposed classification, endomyocardial biopsies are now graded on the basis of - the severity of histologic and immunologic changes. Management of AMR is often - complicated, as patients may have persistent symptoms after treatment, including - a reduction in ejection fraction, restrictive physiology leading to recurrent - heart failure, and accelerated progression of transplant coronary artery disease. - We often rely on therapies to reduce the levels of donor-specific anti-HLA - antibodies, including rituximab and bortezomib, as well as photopheresis to alter - the function of T cells, although such patients may go on to require redo - transplantation. SUMMARY: AMR offers challenges of diagnosis and management, but - recent advances in the detection of antibodies, the interpretation of - endomyocardial biopsies, and the use of therapies directed toward antibody - production offer great promise. In the future, standardization of management - across transplant centers will allow for clinical trials of the effectiveness of - these therapies. -FAU - Kittleson, Michelle M -AU - Kittleson MM -AD - Cedars-Sinai Heart Institute, Los Angeles, California, USA. -FAU - Kobashigawa, Jon A -AU - Kobashigawa JA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Organ Transplant -JT - Current opinion in organ transplantation -JID - 9717388 -RN - 0 (Antibodies) -RN - 0 (HLA Antigens) -SB - IM -MH - Antibodies/*immunology -MH - Graft Rejection/drug therapy/*immunology -MH - HLA Antigens/immunology -MH - Humans -MH - Organ Transplantation/*adverse effects/*methods -MH - *Transplantation Immunology -EDAT- 2012/08/15 06:00 -MHDA- 2013/04/27 06:00 -CRDT- 2012/08/15 06:00 -PHST- 2012/08/15 06:00 [entrez] -PHST- 2012/08/15 06:00 [pubmed] -PHST- 2013/04/27 06:00 [medline] -AID - 10.1097/MOT.0b013e3283577fef [doi] -PST - ppublish -SO - Curr Opin Organ Transplant. 2012 Oct;17(5):551-7. doi: - 10.1097/MOT.0b013e3283577fef. - -PMID- 21627480 -OWN - NLM -STAT- MEDLINE -DCOM- 20110930 -LR - 20110601 -IS - 1744-8298 (Electronic) -IS - 1479-6678 (Linking) -VI - 7 -IP - 3 -DP - 2011 May -TI - Atrial fibrillation in the aging heart: pharmacological therapy and catheter - ablation in the elderly. -PG - 415-23 -LID - 10.2217/fca.11.22 [doi] -AB - The majority of patients with atrial fibrillation (AF) seeking medical treatment - are in the elderly age group and the management of these patients is often - complicated by comorbidities, challenging the pharmacological management of these - patients. Owing to hypertension, congestive heart failure, left ventricular - hypertrophy and coronary artery disease, antiarrhythmic treatment often fails due - to side effects, proarrhythmia or poor rhythm control. In recent years, - radiofrequency catheter ablation has been widely performed as an effective - treatment for recurrent, drug-refractory AF. However, few elderly patients were - included in prior AF catheter ablation studies and the current guidelines for - catheter ablation of AF recommend a conservative approach in the elderly - population owing to the absence of clinical data. However, study results from our - group and others suggest that catheter ablation is a safe and effective treatment - for patients over the age of 65 years with symptomatic, drug-refractory AF and, - therefore, patients should not be excluded from catheter ablation on the basis of - age alone. In this article, we discuss the pharmacological (rhythm control, rate - control and anticoagulation) and catheter management of AF in the elderly - population. -FAU - Haegeli, Laurent M -AU - Haegeli LM -AD - Cardiology Department, Cardiovascular Center, University Hospital of Zurich, - Zurich, Switzerland. laurent.haegeli@usz.ch -FAU - Duru, Firat -AU - Duru F -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Future Cardiol -JT - Future cardiology -JID - 101239345 -RN - 0 (Anti-Arrhythmia Agents) -SB - IM -MH - Age Factors -MH - *Aging -MH - Anti-Arrhythmia Agents/*therapeutic use -MH - Atrial Fibrillation/*drug therapy/pathology/surgery -MH - Catheter Ablation/*methods -MH - Humans -MH - Prevalence -MH - Stroke/prevention & control -EDAT- 2011/06/02 06:00 -MHDA- 2011/10/01 06:00 -CRDT- 2011/06/02 06:00 -PHST- 2011/06/02 06:00 [entrez] -PHST- 2011/06/02 06:00 [pubmed] -PHST- 2011/10/01 06:00 [medline] -AID - 10.2217/fca.11.22 [doi] -PST - ppublish -SO - Future Cardiol. 2011 May;7(3):415-23. doi: 10.2217/fca.11.22. - -PMID- 17389039 -OWN - NLM -STAT- MEDLINE -DCOM- 20071106 -LR - 20181113 -IS - 1750-1172 (Electronic) -IS - 1750-1172 (Linking) -VI - 2 -DP - 2007 Mar 27 -TI - Cirrhotic cardiomyopathy. -PG - 15 -AB - Cirrhotic cardiomyopathy is the term used to describe a constellation of features - indicative of abnormal heart structure and function in patients with cirrhosis. - These include systolic and diastolic dysfunction, electrophysiological changes, - and macroscopic and microscopic structural changes. The prevalence of cirrhotic - cardiomyopathy remains unknown at present, mostly because the disease is - generally latent and shows itself when the patient is subjected to stress such as - exercise, drugs, hemorrhage and surgery. The main clinical features of cirrhotic - cardiomyopathy include baseline increased cardiac output, attenuated systolic - contraction or diastolic relaxation in response to physiologic, pharmacologic and - surgical stress, and electrical conductance abnormalities (prolonged QT - interval). In the majority of cases, diastolic dysfunction precedes systolic - dysfunction, which tends to manifest only under conditions of stress. Generally, - cirrhotic cardiomyopathy with overt severe heart failure is rare. Major stresses - on the cardiovascular system such as liver transplantation, infections and - insertion of transjugular intrahepatic portosystemic stent-shunts (TIPS) can - unmask the presence of cirrhotic cardiomyopathy and thereby convert latent to - overt heart failure. Cirrhotic cardiomyopathy may also contribute to the - pathogenesis of hepatorenal syndrome. Pathogenic mechanisms of cirrhotic - cardiomyopathy are multiple and include abnormal membrane biophysical - characteristics, impaired beta-adrenergic receptor signal transduction and - increased activity of negative-inotropic pathways mediated by cGMP. Diagnosis and - differential diagnosis require a careful assessment of patient history probing - for excessive alcohol, physical examination for signs of hypertension such as - retinal vascular changes, and appropriate diagnostic tests such as exercise - stress electrocardiography, nuclear heart scans and coronary angiography. Current - management recommendations include empirical, nonspecific and mainly supportive - measures. The exact prognosis remains unclear. The extent of cirrhotic - cardiomyopathy generally correlates to the degree of liver insufficiency. - Reversibility is possible (either pharmacological or after liver - transplantation), but further studies are needed. -FAU - Baik, Soon Koo -AU - Baik SK -AD - Dept of Medicine, Yonsei University Wonju College of Medicine, Wonju, South - Korea. baiksk@yonsei.ac.kr -FAU - Fouad, Tamer R -AU - Fouad TR -FAU - Lee, Samuel S -AU - Lee SS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20070327 -PL - England -TA - Orphanet J Rare Dis -JT - Orphanet journal of rare diseases -JID - 101266602 -SB - IM -MH - Animals -MH - Cardiomyopathies/diagnosis/*etiology/physiopathology/therapy -MH - Diagnosis, Differential -MH - Heart Diseases/diagnosis -MH - Humans -MH - Liver Cirrhosis/*complications/physiopathology/surgery -MH - Liver Transplantation -MH - Prognosis -PMC - PMC1847677 -EDAT- 2007/03/29 09:00 -MHDA- 2007/11/07 09:00 -PMCR- 2007/03/27 -CRDT- 2007/03/29 09:00 -PHST- 2007/01/03 00:00 [received] -PHST- 2007/03/27 00:00 [accepted] -PHST- 2007/03/29 09:00 [pubmed] -PHST- 2007/11/07 09:00 [medline] -PHST- 2007/03/29 09:00 [entrez] -PHST- 2007/03/27 00:00 [pmc-release] -AID - 1750-1172-2-15 [pii] -AID - 10.1186/1750-1172-2-15 [doi] -PST - epublish -SO - Orphanet J Rare Dis. 2007 Mar 27;2:15. doi: 10.1186/1750-1172-2-15. - -PMID- 23830344 -OWN - NLM -STAT- MEDLINE -DCOM- 20140626 -LR - 20250529 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 168 -IP - 4 -DP - 2013 Oct 9 -TI - Autologous bone marrow-derived stem cell therapy in heart disease: discrepancies - and contradictions. -PG - 3381-403 -LID - S0167-5273(13)00801-2 [pii] -LID - 10.1016/j.ijcard.2013.04.152 [doi] -AB - BACKGROUND: Autologous bone marrow stem cell therapy is the greatest advance in - the treatment of heart disease for a generation according to pioneering reports. - In response to an unanswered letter regarding one of the largest and most - promising trials, we attempted to summarise the findings from the most innovative - and prolific laboratory. METHOD AND RESULTS: Amongst 48 reports from the group, - there appeared to be 5 actual clinical studies ("families" of reports). Duplicate - or overlapping reports were common, with contradictory experimental design, - recruitment and results. Readers cannot always tell whether a study is randomised - versus not, open-controlled or blinded placebo-controlled, or lacking a control - group. There were conflicts in recruitment dates, criteria, sample sizes, - million-fold differences in cell counts, sex reclassification, fractional numbers - of patients and conflation of competitors' studies with authors' own. - Contradictory results were also common. These included arithmetical - miscalculations, statistical errors, suppression of significant changes, - exaggerated description of own findings, possible silent patient deletions, - fractional numbers of coronary arteries, identical results with contradictory - sample sizes, contradictory results with identical sample sizes, misrepresented - survival graphs and a patient with a negative NYHA class. We tabulate over 200 - discrepancies amongst the reports. The 5 family-flagship papers (Strauer 2002, - STAR, IACT, ABCD, BALANCE) have had 2665 citations. Of these, 291 citations were - to the pivotal STAR or IACT-JACC papers, but 97% of their eligible citing papers - did not mention any discrepancies. Five meta-analyses or systematic reviews - covered these studies, but none described any discrepancies and all resolved - uncertainties by undisclosed methods, in mutually contradictory ways. - Meta-analysts disagreed whether some studies were randomised or - "accepter-versus-rejecter". Our experience of presenting the discrepancies to - journals is that readers may remain unaware of such problems. CONCLUSIONS: Modern - reporting of clinical research can still be imperfect. The scientific literature - absorbs such reports largely uncritically. Even meta-analyses seem to resolve - contradictions haphazardly. Discrepancies communicated to journals are not - guaranteed to reach the scientific community. Journals could consider - prioritising systematic reporting of queries even if seemingly minor, and - establishing a policy of "habeas data". -CI - Copyright © 2013 Elsevier Ireland Ltd. All rights reserved. -FAU - Francis, Darrel P -AU - Francis DP -AD - National Heart and Lung Institute, Imperial College London, UK. -FAU - Mielewczik, Michael -AU - Mielewczik M -FAU - Zargaran, David -AU - Zargaran D -FAU - Cole, Graham D -AU - Cole GD -LA - eng -GR - FS/10/38/28268/BHF_/British Heart Foundation/United Kingdom -GR - FS/12/12/29294/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Review -DEP - 20130702 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -SB - IM -CIN - Int J Cardiol. 2013 Sep 30;168(2):636-7. doi: 10.1016/j.ijcard.2013.04.192. PMID: - 23701933 -MH - Bone Marrow Transplantation/*methods/*trends -MH - Clinical Trials as Topic/methods/trends -MH - Heart Diseases/*diagnosis/epidemiology/*surgery -MH - Humans -MH - Stem Cell Transplantation/methods/trends -MH - Transplantation, Autologous -OTO - NOTNLM -OT - Adult stem cells -OT - Cardiac regeneration -OT - Cognitive dissonance -OT - Inattentional blindness -OT - Meta-analysis -EDAT- 2013/07/09 06:00 -MHDA- 2014/06/27 06:00 -CRDT- 2013/07/09 06:00 -PHST- 2013/01/11 00:00 [received] -PHST- 2013/04/11 00:00 [revised] -PHST- 2013/04/12 00:00 [accepted] -PHST- 2013/07/09 06:00 [entrez] -PHST- 2013/07/09 06:00 [pubmed] -PHST- 2014/06/27 06:00 [medline] -AID - S0167-5273(13)00801-2 [pii] -AID - 10.1016/j.ijcard.2013.04.152 [doi] -PST - ppublish -SO - Int J Cardiol. 2013 Oct 9;168(4):3381-403. doi: 10.1016/j.ijcard.2013.04.152. - Epub 2013 Jul 2. - -PMID- 21099685 -OWN - NLM -STAT- MEDLINE -DCOM- 20110608 -LR - 20211020 -IS - 1473-6543 (Electronic) -IS - 1062-4821 (Linking) -VI - 20 -IP - 1 -DP - 2011 Jan -TI - Role of renalase in the regulation of blood pressure and the renal dopamine - system. -PG - 31-6 -LID - 10.1097/MNH.0b013e3283412721 [doi] -AB - PURPOSE OF REVIEW: Renalase is a secreted amine oxidase that is synthesized in - the kidney, and that metabolizes circulating catecholamines. Tissue and plasma - renalase levels are decreased in models of chronic kidney disease. Recent data - indicate that renalase deficiency is associated with increased blood pressure and - elevated circulating catecholamines. The mechanisms of hypertension in renalase - deficiency and the possibility that renalase regulates the renal dopamine system - are discussed. RECENT FINDINGS: Characterization of the renalase knockout mouse - model revealed that renalase deficiency increases SBP and DBP. Renal and cardiac - functions are unaffected, but there is evidence of sympathetic activation, with - elevation of plasma and urine catecholamines. Renalase is continually excreted in - urine, and is enzymatically active and could modulate catecholamines levels in - tubular fluid. Renalase expression is modulated by salt intake, and recombinant - renalase has a potent and prolonged hypotensive effect on blood pressure in Dahl - salt-sensitive rats and rats with chronic kidney disease. Plasma renalase levels - are inversely associated with SBP in patients with resistant hypertension. A - functional mutation in renalase (Glu37Asp) associated with essential hypertension - also predicts more severe cardiac hypertrophy, dysfunction, and ischemia in - individuals with stable coronary artery disease, comparable blood pressure and - normal renal function. SUMMARY: Urinary renalase metabolizes urinary - catecholamines, and perhaps regulates dopamine concentration in luminal fluid, - and modulate proximal tubular sodium transport. Renalase deficiency is associated - with increased sympathetic tone and resistant hypertension. Recombinant renalase - is a potent antihypertensive agent in Dahl salt-sensitive rats and in rats with - chronic kidney disease. -FAU - Desir, Gary V -AU - Desir GV -AD - Department of Medicine, Yale University School of Medicine, New Haven, CT - 06520-8029, USA. gary.desir@yale.edu -LA - eng -GR - R01 DK081037/DK/NIDDK NIH HHS/United States -GR - 1RC1DK086402/DK/NIDDK NIH HHS/United States -GR - 1RC1DK086465/DK/NIDDK NIH HHS/United States -GR - 1R01DK081037/DK/NIDDK NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - England -TA - Curr Opin Nephrol Hypertens -JT - Current opinion in nephrology and hypertension -JID - 9303753 -RN - 0 (Sodium, Dietary) -RN - 0 (Sodium-Hydrogen Exchanger 3) -RN - 0 (Sodium-Hydrogen Exchangers) -RN - 9NEZ333N27 (Sodium) -RN - EC 1.4.3.4 (Monoamine Oxidase) -RN - EC 1.4.3.4. (renalase) -RN - VTD58H1Z2X (Dopamine) -SB - IM -MH - Animals -MH - *Blood Pressure -MH - Dopamine/*physiology -MH - Heart Failure/etiology -MH - Homeostasis -MH - Humans -MH - Hypertension/etiology -MH - Hypertrophy, Left Ventricular/etiology -MH - Kidney/*metabolism -MH - Kinetics -MH - Monoamine Oxidase/analysis/genetics/*physiology -MH - Rats -MH - Sodium/metabolism -MH - Sodium, Dietary/pharmacology -MH - Sodium-Hydrogen Exchanger 3 -MH - Sodium-Hydrogen Exchangers/physiology -EDAT- 2010/11/26 06:00 -MHDA- 2011/06/09 06:00 -CRDT- 2010/11/25 06:00 -PHST- 2010/11/25 06:00 [entrez] -PHST- 2010/11/26 06:00 [pubmed] -PHST- 2011/06/09 06:00 [medline] -AID - 10.1097/MNH.0b013e3283412721 [doi] -PST - ppublish -SO - Curr Opin Nephrol Hypertens. 2011 Jan;20(1):31-6. doi: - 10.1097/MNH.0b013e3283412721. - -PMID- 17497086 -OWN - NLM -STAT- MEDLINE -DCOM- 20070817 -LR - 20070514 -IS - 0723-5003 (Print) -IS - 0723-5003 (Linking) -VI - 102 -IP - 5 -DP - 2007 May 15 -TI - [Congenital left ventricular aneurysms and diverticula. Pathophysiology, clinical - relevance, and treatment]. -PG - 358-65 -AB - A congenital left ventricular aneurysm or diverticulum is a rare cardiac - malformation described in 418 cases since the first description in 1816, being - associated with other cardiac, vascular or thoracoabdominal abnormalities in - about 75%. It appears to be a developmental anomaly, starting in the 4th - embryonic week. Diagnosis can be made after exclusion of coronary artery disease, - local or systemic inflammation or traumatic causes as well as cardiomyopathies. - Clinically, most congenital left ventricular aneurysms and diverticula are - asymptomatic, but some of them may cause systemic embolization, heart failure, - valvular regurgitation, ventricular wall rupture, ventricular tachycardia, or - sudden cardiac death. Diagnosis is established by imaging studies such as - echocardiography, magnetic resonance imaging or left ventricular angiography, - visualizing the structural changes and accompanying abnormalities. Mode of - treatment has to be individually tailored and depends on clinical presentation, - accompanying abnormalities and possible complications, options include surgical - resection, especially in symptomatic patients, anticoagulation after systemic - embolization, radiofrequency ablation or implantation of a cardioverter - defibrillator in case of symptomatic ventricular tachycardias, occasionally - combined with class I or III antiarrhythmic drugs. Because of the usually benign - course of congenital left ventricular aneurysms and diverticula in the adulthood, - most of them can be managed conservatively. -FAU - Ohlow, Marc-Alexander -AU - Ohlow MA -AD - Klinik für Kardiologie, Zentralklinik Bad Berka, Robert-Koch-Allee 9, 99437, Bad - Berka, Germany. m.ohlow.kar@zentralklinik-bad-berka.de -FAU - Secknus, Maria-Anna -AU - Secknus MA -FAU - Geller, Johann-Christoph -AU - Geller JC -FAU - von Korn, Hubertus -AU - von Korn H -FAU - Lauer, Bernward -AU - Lauer B -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Kongenitale linksventrikuläre Aneurysmata und Divertikel des Erwachsenen. - Pathophysiologie, klinische Präsentation und Therapieoptionen. -PL - Germany -TA - Med Klin (Munich) -JT - Medizinische Klinik (Munich, Germany : 1983) -JID - 8303501 -SB - IM -MH - Adolescent -MH - Adult -MH - Aged -MH - Angiography -MH - Diagnosis, Differential -MH - Diverticulum/*congenital -MH - Echocardiography, Transesophageal -MH - Female -MH - Heart Aneurysm/*congenital/diagnosis/physiopathology/therapy -MH - Heart Defects, Congenital/*diagnosis/physiopathology/therapy -MH - Heart Ventricles/physiopathology -MH - Humans -MH - Incidental Findings -MH - Magnetic Resonance Imaging -MH - Male -MH - Middle Aged -MH - Prognosis -MH - Ventricular Dysfunction, Left/*congenital/diagnosis/physiopathology/therapy -RF - 129 -EDAT- 2007/05/15 09:00 -MHDA- 2007/08/19 09:00 -CRDT- 2007/05/15 09:00 -PHST- 2006/10/13 00:00 [received] -PHST- 2007/03/23 00:00 [revised] -PHST- 2007/05/15 09:00 [pubmed] -PHST- 2007/08/19 09:00 [medline] -PHST- 2007/05/15 09:00 [entrez] -AID - 10.1007/s00063-007-1034-3 [doi] -PST - ppublish -SO - Med Klin (Munich). 2007 May 15;102(5):358-65. doi: 10.1007/s00063-007-1034-3. - -PMID- 19475783 -OWN - NLM -STAT- MEDLINE -DCOM- 20090619 -LR - 20211020 -IS - 1178-2048 (Electronic) -IS - 1176-6344 (Print) -IS - 1176-6344 (Linking) -VI - 5 -IP - 1 -DP - 2009 -TI - Improving outcomes in patients undergoing percutaneous coronary intervention: - role of prasugrel. -PG - 475-81 -AB - Dual oral antiplatelet therapy, aspirin plus thienopyridine, has permitted a - rapid increase in the use of coronary intervention procedures. Clopidogrel is the - thienopyridine of choice for dual antiplatelet therapy in patients treated with - percutaneous coronary intervention. However, there are two issues with - clopidogrel: (1) clopidogrel's antiplatelet activity is delayed because the drug - needs to be metabolized into its active form and (2) variability in patient - response to clopidogrel has been demonstrated. To overcome these shortcomings of - clopidogrel, new more potent inhibitors of P2Y12 receptors, which have a more - rapid onset of action have been introduced for clinical evaluation. This article - is a nonexhaustive review of the literature and concentrates on prasugrel, a - third-generation, oral thienopyridine. The purpose is to summarize the current - knowledge about the benefits and risks of prasugrel and to outline the most - prudent strategies for the drug's clinical use. -FAU - Motovska, Zuzana -AU - Motovska Z -AD - Third Medical Faculty of Charles University and University Hospital Kralovske - Vinohrady, Prague, Czech Republic. zuzana.motovska@iex.cz -FAU - Widimsky, Petr -AU - Widimsky P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - New Zealand -TA - Vasc Health Risk Manag -JT - Vascular health and risk management -JID - 101273479 -RN - 0 (Piperazines) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Thiophenes) -RN - A74586SNO7 (Clopidogrel) -RN - G89JQ59I13 (Prasugrel Hydrochloride) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Administration, Oral -MH - Angioplasty, Balloon, Coronary/*adverse effects/instrumentation -MH - Aspirin/therapeutic use -MH - Clopidogrel -MH - Coronary Thrombosis/etiology/*prevention & control -MH - Diabetes Complications/therapy -MH - Drug Resistance/genetics -MH - Drug Therapy, Combination -MH - Humans -MH - Myocardial Infarction/*therapy -MH - Piperazines/administration & dosage/adverse effects/*therapeutic use -MH - Platelet Aggregation Inhibitors/administration & dosage/adverse - effects/*therapeutic use -MH - Prasugrel Hydrochloride -MH - Risk Assessment -MH - Risk Factors -MH - Stents -MH - Thiophenes/administration & dosage/adverse effects/*therapeutic use -MH - Ticlopidine/analogs & derivatives/therapeutic use -MH - Treatment Outcome -PMC - PMC2686264 -EDAT- 2009/05/30 09:00 -MHDA- 2009/06/20 09:00 -PMCR- 2009/05/21 -CRDT- 2009/05/30 09:00 -PHST- 2009/05/30 09:00 [entrez] -PHST- 2009/05/30 09:00 [pubmed] -PHST- 2009/06/20 09:00 [medline] -PHST- 2009/05/21 00:00 [pmc-release] -AID - vhrm-5-475 [pii] -AID - 10.2147/vhrm.s3969 [doi] -PST - ppublish -SO - Vasc Health Risk Manag. 2009;5(1):475-81. doi: 10.2147/vhrm.s3969. - -PMID- 22239632 -OWN - NLM -STAT- MEDLINE -DCOM- 20120727 -LR - 20211021 -IS - 1875-6212 (Electronic) -IS - 1570-1611 (Linking) -VI - 10 -IP - 3 -DP - 2012 May -TI - Regenerative therapies for improving myocardial perfusion in patients with - cardiovascular disease: failure to meet expectations but optimism for the future. -PG - 300-9 -AB - Cardiovascular disease continues to be a major cause of death in the Western - world and has been extending into areas previously seemingly immune to its - effects. Catheter-based interventions and coronary artery bypass surgery have - markedly improved cardiovascular health, but a number of patients with coronary - artery disease cannot undergo repeated interventions or they receive an - incomplete revascularization with standard revascularization methods, which has - been associated with a poor clinical outcome. Despite early demonstration of - improvement in myocardial perfusion and function with growth factor, gene therapy - or cellular therapies, clinical studies have found little if any real benefit. - The discordance between positive pre-clinical studies and essentially negative - clinical trials may in part be explained by a number of factors including - abnormal vascular signaling, oxidative stress, a hostile local myocardial - environment and technical issues related to the administration of these - therapies. Patients with end-stage coronary disease are vastly different from the - young, healthy animals that are generally used for pre-clinical testing. The - presence of diabetes, hypercholesterolemia, and other conditions associated with - endothelial dysfunction and coronary disease and altered vascular signaling can - significantly limit the effectiveness of growth factors on the development of - collateral vessels. This paper summarizes the results of regenerative therapies - for the treatment of coronary disease and discusses the reasons why growth factor - protein, gene therapies and cellular therapies have not been overall successful - to date. -FAU - Sellke, Frank W -AU - Sellke FW -AD - Division of Cardiothoracic Surgery, Alpert Medical School of Brown University, - Providence, RI 02903, USA. fsellke@lifespan.org -FAU - Lassaletta, Antonio D -AU - Lassaletta AD -FAU - Robich, Michael P -AU - Robich MP -FAU - Chu, Louis M -AU - Chu LM -FAU - Ruel, Marc -AU - Ruel M -LA - eng -GR - R01 HL069024/HL/NHLBI NIH HHS/United States -GR - R01 HL085647/HL/NHLBI NIH HHS/United States -GR - T32 HL076130/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Vasc Pharmacol -JT - Current vascular pharmacology -JID - 101157208 -RN - 0 (Intercellular Signaling Peptides and Proteins) -SB - IM -MH - Animals -MH - Cardiovascular Diseases/physiopathology/*therapy -MH - Cell- and Tissue-Based Therapy/*methods -MH - Disease Models, Animal -MH - Genetic Therapy/*methods -MH - Humans -MH - Intercellular Signaling Peptides and Proteins/metabolism -MH - Regeneration -MH - Signal Transduction -EDAT- 2012/01/14 06:00 -MHDA- 2012/07/28 06:00 -CRDT- 2012/01/14 06:00 -PHST- 2011/05/14 00:00 [received] -PHST- 2011/06/21 00:00 [revised] -PHST- 2011/10/19 00:00 [accepted] -PHST- 2012/01/14 06:00 [entrez] -PHST- 2012/01/14 06:00 [pubmed] -PHST- 2012/07/28 06:00 [medline] -AID - CVP-EPUB-20120113-008 [pii] -AID - 10.2174/157016112799959396 [doi] -PST - ppublish -SO - Curr Vasc Pharmacol. 2012 May;10(3):300-9. doi: 10.2174/157016112799959396. - -PMID- 18773746 -OWN - NLM -STAT- MEDLINE -DCOM- 20081017 -LR - 20191210 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 9 -IP - 4 Suppl 1 -DP - 2008 Apr -TI - [Cardiovascular risk and cardiometabolic risk: an epidemiological evaluation]. -PG - 6S-17S -AB - On the basis of a critical literature review, this article deals with the - concepts of global cardiovascular risk and cardiometabolic risk, pointing out - their links but also their unresolved issues and discussing their usefulness in - clinical practice. The global cardiovascular risk is the probability of suffering - from a coronary event or stroke in a given period of time and in this sense it is - an absolute risk, generally reported as percentage at 10 years. Usually risk - functions are used, derived from longitudinal studies of healthy people at - baseline. They consider some factors that are coherently linked with events in - population analyses: among these there are some metabolic factors (total - cholesterol, HDL cholesterol, fasting blood glucose), some biological factors - (blood pressure) and some lifestyle factors (tobacco smoking), all modifiable - beyond those non-modifiable like age and gender. The chosen factors must be - independent at multivariate analysis, simple and standardized to measure, and - contribute to significantly increase the risk-function predictivity. To be - reliable, these risk functions must be derived from the same population where - they will be later administered. For this reason the Italian Progetto CUORE, in - the longitudinal study section, built a database of risk factors from - longitudinal comparable studies started between the mid '80s and '90s and - followed up the participants for cardiovascular mortality and morbidity to - estimate the Italian global cardiovascular risk (first coronary or - cerebrovascular event) for men and women. Two tools have been produced, the risk - charts and a score software (see www.cuore.iss.it). The ongoing epidemics of - obesity and diabetes and the fact that diabetes is associated with classical risk - factors like hypertension and dyslipidemia induced the American Diabetes - Association and the American Heart Association to launch a "call to action" to - prevent both cardiovascular disease and diabetes. In this paper, as - cardiometabolic risk factors were considered those "closely related to diabetes - and cardiovascular disease: fasting/postprandial hyperglycemia, - overweight/obesity, elevated systolic and diastolic blood pressure, and - dyslipidemia". The association among the cardiometabolic risk factors has been - known for a long time, and much of their etiology has been ascribed to insulin - resistance. Also, the fact that these "metabolic" abnormalities can cluster in - many individuals gave rise to the term "metabolic syndrome", a construct embraced - by many organizations but questioned by other authors. From an epidemiological - point of view the metabolic syndrome seems to increase modestly the - cardiovascular risk, whereas in non-diabetic individuals it predicts diabetes - much more efficiently. Many studies have compared the performance of the - classical cardiovascular evaluation tools (the Framingham risk score, the SCORE - charts, the Progetto CUORE score) and metabolic syndrome in cardiovascular - disease prediction. Usually in people at high risk the presence of the metabolic - syndrome does not improve the risk, whereas in people at lower risk its presence - increases significantly the chances of cardiovascular disease. Many studies have - shown that positive lifestyle interventions markedly reduce the rate of - progression of type 2 diabetes. Also some drugs were tested for diabetes - prevention, usually in people with impaired glucose tolerance. Oral diabetes - drugs considered together (acarbose, metformin, flumamine, glipizide, phenformin) - were less effective than lifestyle interventions, with different results among - the drugs; the antiobesity drug orlistat gave similar results to lifestyle - interventions. In Italy an appropriate approach to cardiovascular disease and - diabetes prevention may be that of first evaluating the global cardiovascular - risk using the charts or the score software of the Progetto CUORE, because - high-risk subjects (> or =20%) must be treated aggressively independently of the - presence of the metabolic syndrome; as a second step the metabolic syndrome may - be sought, because it increases the risk; finally some attention should be paid - to non-diabetic hyperglycemic individuals. -FAU - Vanuzzo, Diego -AU - Vanuzzo D -AD - Centro di Prevenzione Cardiovascolare, ASS4, Udine. diego.vanuzzo@sanita.fvg.it -FAU - Pilotto, Lorenza -AU - Pilotto L -FAU - Mirolo, Renata -AU - Mirolo R -FAU - Pirelli, Salvatore -AU - Pirelli S -LA - ita -PT - Comparative Study -PT - Evaluation Study -PT - Journal Article -PT - Review -TT - Rischio cardiovascolare e rischio cardiometabolico: una valutazione - epidemiologica. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -RN - 0 (Blood Glucose) -RN - 0 (Cholesterol, HDL) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Adult -MH - Age Factors -MH - Aged -MH - Blood Glucose/analysis -MH - Cardiovascular Diseases/blood/*epidemiology/mortality/prevention & control -MH - Cholesterol/blood -MH - Cholesterol, HDL/blood -MH - Diabetes Mellitus/epidemiology -MH - Exercise -MH - Female -MH - Humans -MH - Italy/epidemiology -MH - Life Style -MH - Longitudinal Studies -MH - Male -MH - *Metabolic Syndrome/blood -MH - Middle Aged -MH - Multivariate Analysis -MH - Obesity/epidemiology -MH - Prognosis -MH - Risk Factors -MH - Sex Factors -MH - Software -MH - Time Factors -RF - 85 -EDAT- 2008/09/09 09:00 -MHDA- 2008/10/18 09:00 -CRDT- 2008/09/09 09:00 -PHST- 2008/09/09 09:00 [pubmed] -PHST- 2008/10/18 09:00 [medline] -PHST- 2008/09/09 09:00 [entrez] -PST - ppublish -SO - G Ital Cardiol (Rome). 2008 Apr;9(4 Suppl 1):6S-17S. - -PMID- 20470468 -OWN - NLM -STAT- MEDLINE -DCOM- 20100901 -LR - 20100517 -IS - 1646-0758 (Electronic) -IS - 0870-399X (Linking) -VI - 23 -IP - 2 -DP - 2010 Mar-Apr -TI - [Acute coronary syndrome in primary health care]. -PG - 213-22 -AB - INTRODUCTION: It is thought that in the XXI century cardiovascular disease will - become the main cause of disability ant death in the world. Cardiac complaints - are very common in clinical practice and the high prevalence of coronary disease - and its sequels puts the family doctor in the frontline of the struggle against - this pathology. This review pretends to inform about the presentation, diagnosis - and urgent approach of the acute coronary syndrome as well as the need of - continuity of care and secondary prevention. REVIEW: Coronary disease can appear - as a myocardial infarction and occurs predominantly in a population susceptible - to atherogenesis due to various risk factors. Acute thoracic discomfort is the - most usual clinical presentation and the initial evaluation intends to determine - its cause through a brief clinical history, physical exam, electrocardiogram and - dosing of markers of cardiac necrosis. After confirmation of the diagnosis the - patient is submitted to urgent treatment that depends on the form of presentation - of the acute coronary syndrome. It usually involves study of coronary anatomy by - coronariography and revascularization. After the acute event the coronary patient - must initiate a medical therapy with drugs that reduce mortality (antiplatelet - therapy, beta-blockers, angiotensin converting enzyme inhibitors and statins) and - aggressively control the modifiable risk factors. CONCLUSION: The family doctor - has a primordial role in continuing care initiated at the hospital and in - implementing aggressive secondary prevention measures. By knowing and putting - them into practice, the family doctor takes his part in reducing the burden of - cardiovascular diseases and in controlling this epidemic. -FAU - Macedo, António -AU - Macedo A -AD - Medicina Geral e Familiar, Centro de Saúde da Senhora da Hora (ULS Matosinhos). -FAU - Rosa, Fernando -AU - Rosa F -LA - por -PT - English Abstract -PT - Journal Article -PT - Review -TT - O síndrome coronário agudo nos cuidados de saúde primários. -DEP - 20100414 -PL - Portugal -TA - Acta Med Port -JT - Acta medica portuguesa -JID - 7906803 -SB - IM -MH - Acute Coronary Syndrome/*diagnosis/*therapy -MH - Humans -MH - Primary Health Care -RF - 29 -EDAT- 2010/05/18 06:00 -MHDA- 2010/09/02 06:00 -CRDT- 2010/05/18 06:00 -PHST- 2008/06/18 00:00 [received] -PHST- 2008/07/24 00:00 [accepted] -PHST- 2010/05/18 06:00 [entrez] -PHST- 2010/05/18 06:00 [pubmed] -PHST- 2010/09/02 06:00 [medline] -PST - ppublish -SO - Acta Med Port. 2010 Mar-Apr;23(2):213-22. Epub 2010 Apr 14. - -PMID- 23861452 -OWN - NLM -STAT- MEDLINE -DCOM- 20130927 -LR - 20161125 -IS - 1942-0080 (Electronic) -IS - 1941-9651 (Linking) -VI - 6 -IP - 4 -DP - 2013 Jul -TI - Computed tomographic imaging of transcatheter aortic valve replacement for - prediction and prevention of procedural complications. -PG - 597-605 -LID - 10.1161/CIRCIMAGING.113.000334 [doi] -FAU - Leipsic, Jonathon -AU - Leipsic J -AD - Department of Medical Imaging and Medicine, St Paul's Hospital, University of - British Columbia, Vancouver, BC, Canada. jleipsic@providencehealth.bc.ca -FAU - Yang, Tae-Hyun -AU - Yang TH -FAU - Min, James K -AU - Min JK -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Circ Cardiovasc Imaging -JT - Circulation. Cardiovascular imaging -JID - 101479935 -RN - Aortic Valve, Calcification of -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Aorta/injuries -MH - Aortic Rupture/etiology/prevention & control -MH - Aortic Valve/diagnostic imaging/pathology -MH - Aortic Valve Insufficiency/etiology/prevention & control -MH - Aortic Valve Stenosis/diagnostic imaging/*therapy -MH - Arrhythmias, Cardiac/etiology/prevention & control -MH - Calcinosis/diagnostic imaging/*therapy -MH - *Cardiac Catheterization/adverse effects -MH - Coronary Occlusion/etiology/prevention & control -MH - Echocardiography, Doppler, Color -MH - Female -MH - Femoral Artery/injuries -MH - Heart Valve Prosthesis Implantation/adverse effects/*methods -MH - Humans -MH - Male -MH - Multidetector Computed Tomography -MH - Predictive Value of Tests -MH - Radiography, Interventional/*methods -MH - Risk Assessment -MH - Risk Factors -MH - *Tomography, X-Ray Computed -MH - Treatment Outcome -MH - Vascular System Injuries/etiology/prevention & control -OTO - NOTNLM -OT - computed tomography -OT - image integration -OT - outcomes research -OT - three-dimensional imaging -EDAT- 2013/07/19 06:00 -MHDA- 2013/09/28 06:00 -CRDT- 2013/07/18 06:00 -PHST- 2013/07/18 06:00 [entrez] -PHST- 2013/07/19 06:00 [pubmed] -PHST- 2013/09/28 06:00 [medline] -AID - CIRCIMAGING.113.000334 [pii] -AID - 10.1161/CIRCIMAGING.113.000334 [doi] -PST - ppublish -SO - Circ Cardiovasc Imaging. 2013 Jul;6(4):597-605. doi: - 10.1161/CIRCIMAGING.113.000334. - -PMID- 26587428 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20151120 -LR - 20200930 -IS - 2235-8676 (Print) -IS - 2235-8668 (Electronic) -IS - 2235-8668 (Linking) -VI - 1 -IP - 2 -DP - 2013 Oct -TI - Role of Pulsatile Hemodynamics in Acute Heart Failure: Implications for Type 1 - Cardiorenal Syndrome. -PG - 89-96 -LID - 10.1159/000354107 [doi] -AB - Heart failure has become a major health problem worldwide with a substantial - financial burden mainly from hospitalization due to acute heart failure syndrome - (AHFS). A considerable number of patients hospitalized for the treatment of AHFS - experience significant worsening of renal function, which is now recognized as - type 1 cardiorenal syndrome (CRS) and is associated with worse outcomes. - Currently known risk factors for acute CRS in AHFS include obesity, cachexia, - hypertension, diabetes, proteinuria, uremic solute retention, anemia, and - repeated subclinical acute kidney injury events. Venous renal congestion due to - hemodynamic changes also contributes to type 1 CRS. Vascular aging and its - aggravated pulsatile hemodynamics have been shown to be involved in the - pathogenesis of AHFS. Suboptimal recovery of the perturbation of the pulsatile - hemodynamics may predict 6-month post-discharge cardiovascular outcomes in - patients hospitalized due to AHFS. Furthermore, on-admission pulsatile - hemodynamics may also be helpful to identify and stratify patients with - aggravated pulsatile hemodynamics who may benefit from customized therapy. There - are close interplays and feedback loops between heart and kidney dysfunction. - Increased arterial stiffness accelerates pulse wave velocity and causes an - earlier return of the reflected wave, resulting in higher systolic, lower - diastolic, and higher pulse pressure in the central aorta and renal arteries. - Increased pulsatile hemodynamics have been associated with deterioration of renal - function in subjects with a high coronary risk and patients with hypertension or - chronic kidney disease. Thus, there is a potential role of vascular - aging/pulsatile hemodynamics in the pathophysiological pathways of acute CRS in - AHFS. -FAU - Sung, Shih-Hsien -AU - Sung SH -AD - Department of Medicine, Taipei, Taiwan, ROC ; Department of Medicine, National - Yang-Ming University, Taipei, Taiwan, ROC ; Institute of Public Health and - Community Medicine Research Center, National Yang-Ming University, Taipei, - Taiwan, ROC. -FAU - Chen, Chen-Huan -AU - Chen CH -AD - Department of Medical Research and Education, Taipei Veterans General Hospital, - Taipei, Taiwan, ROC ; Institute of Public Health and Community Medicine Research - Center, National Yang-Ming University, Taipei, Taiwan, ROC. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130910 -PL - Switzerland -TA - Pulse (Basel) -JT - Pulse (Basel, Switzerland) -JID - 101644596 -PMC - PMC4315344 -OTO - NOTNLM -OT - Acute heart failure syndrome -OT - Cardiorenal syndrome -OT - Pulsatile hemodynamics -OT - Vascular aging -EDAT- 2013/10/01 00:00 -MHDA- 2013/10/01 00:01 -PMCR- 2013/09/10 -CRDT- 2015/11/21 06:00 -PHST- 2015/11/21 06:00 [entrez] -PHST- 2013/10/01 00:00 [pubmed] -PHST- 2013/10/01 00:01 [medline] -PHST- 2013/09/10 00:00 [pmc-release] -AID - pls-0001-0089 [pii] -AID - 10.1159/000354107 [doi] -PST - ppublish -SO - Pulse (Basel). 2013 Oct;1(2):89-96. doi: 10.1159/000354107. Epub 2013 Sep 10. - -PMID- 21523383 -OWN - NLM -STAT- MEDLINE -DCOM- 20120419 -LR - 20220330 -IS - 1573-7322 (Electronic) -IS - 1382-4147 (Linking) -VI - 17 -IP - 1 -DP - 2012 Jan -TI - The paradox of low BNP levels in obesity. -PG - 81-96 -LID - 10.1007/s10741-011-9249-z [doi] -AB - The aim of this review is to analyze in detail some possible pathophysiological - mechanisms linking obesity and cardiac endocrine function, in order to try to - explain the negative association previously observed between BMI and BNP values - in both healthy subjects and patients with cardiovascular diseases. In - particular, we discuss the hypothesis that the response of the cardiac endocrine - system is the integrated resultant of several and contrasting physiological and - pathological interactions, including the effects of peptide and steroid hormones, - cytokines, cardiovascular hemodynamics, clinical conditions, and pharmacological - treatment. Several studies suggested that gonadal function regulates both body - fat distribution and cardiac endocrine function. Visceral fat expansion can - increase the clearance of active natriuretic peptides by means of an increased - expression of clearance receptors on adipocytes, and in this way, it may - contribute to decrease the activity of the cardiac endocrine system. Moreover, - obesity is associated with ectopic lipid deposition even in the heart, which may - directly exert a lipotoxic effect on the myocardium by secreting in loco several - cytokines and adipokines. Obese subjects are frequently treated for hypertension - and coronary artery disease. Pharmacological treatment reduces plasma level of - cardiac natriuretic peptides, and this effect may explain almost in part the - lower BNP levels of some asymptomatic subjects with increased BMI values. At - present time, it is not possible to give a unique and definitive answer to the - crucial question concerning the inverse relationship between the amount of - visceral fat distribution and BNP levels. Our explanation for these - unsatisfactory results is that the cardiac endocrine response is always the - integrated resultant of several pathophysiological interactions. However, only - few variables can be studied together; as a result, it is not possible to perform - a complete evaluation of pathophysiological mechanisms under study. We are still - not able to well integrate these multiple information together; therefore, we - should learn to do it. -FAU - Clerico, Aldo -AU - Clerico A -AD - Laboratory of Cardiovascular Endocrinology and Cell Biology, Fondazione - CNR-Regione Toscana Gabriele Monasterio, Scuola Superiore Sant'Anna, Via Trieste - 41, 56126 Pisa, Italy. clerico@ifc.cnr.it -FAU - Giannoni, Alberto -AU - Giannoni A -FAU - Vittorini, Simona -AU - Vittorini S -FAU - Emdin, Michele -AU - Emdin M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Brain-Derived Neurotrophic Factor) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -SB - IM -MH - Body Mass Index -MH - Brain-Derived Neurotrophic Factor/metabolism -MH - Case-Control Studies -MH - Heart Failure/complications/*physiopathology -MH - Humans -MH - Natriuretic Peptide, Brain/*metabolism -MH - Obesity/complications/*physiopathology -EDAT- 2011/04/28 06:00 -MHDA- 2012/04/20 06:00 -CRDT- 2011/04/28 06:00 -PHST- 2011/04/28 06:00 [entrez] -PHST- 2011/04/28 06:00 [pubmed] -PHST- 2012/04/20 06:00 [medline] -AID - 10.1007/s10741-011-9249-z [doi] -PST - ppublish -SO - Heart Fail Rev. 2012 Jan;17(1):81-96. doi: 10.1007/s10741-011-9249-z. - -PMID- 23324829 -OWN - NLM -STAT- MEDLINE -DCOM- 20140214 -LR - 20160511 -IS - 2047-2412 (Electronic) -IS - 2047-2404 (Linking) -VI - 14 -IP - 6 -DP - 2013 Jun -TI - Prediction of ventricular arrhythmias using cardiovascular magnetic resonance. -PG - 518-25 -LID - 10.1093/ehjci/jes302 [doi] -AB - Ventricular tachycardia (VT) is the commonest cause of sudden cardiac death (SCD) - in developed countries. Coronary artery disease (CAD) is the most frequent cause - of VT in individuals over the age of 30, while hypertrophic cardiomyopathy (HCM), - myocarditis and congenital heart disease in those below 30 years of age. Cardiac - magnetic resonance (CMR), a non-invasive, non-radiating technique, can reliably - detect the changes in ventricular volumes and the ejection fraction that can be - predictive of VT/SCD. Furthermore, the capability of CMR to perform tissue - characterization and detect oedema, fat and fibrotic substrate, using late - gadolinium enhanced images (LGE), can predict VT/SCD in both ischaemic and - non-ischaemic cardiomyopathy. The extent of LGE in HCM is correlated with risk - factors of SCD and the likelihood of inducible VT. In idiopathic-dilated - cardiomyopathy, the presence of midwall fibrosis, assessed by CMR, also predicts - SCD/VT. Additionally, in arrhythmogenic right ventricle (RV) - dysplasia/cardiomyopathy, CMR has an excellent correlation with histopathology - and predicted inducible VT on programmed electrical stimulation, suggesting a - possible role in evaluation and diagnosis of these patients. A direct correlation - between LGE and VT prediction has been identified only in chronic Chagas' heart - disease, but not in viral myocarditis. In CAD, infarct size is the strongest - predictor of VT inducibility. The peri-infarct zone may also play a role; - however, further studies are needed for definite conclusions. Left ventricle, RV, - right ventricular outflow tract (RVOT) function, pulmonary regurgitation and LGE - around the infundibular patch and RV anterior wall play an important role in the - VT prediction in repaired Tetralogy of Fallot. Finally, in treated transposition - of great arteries, the extent of LGE in the systemic RV correlates with age, - ventricular dysfunction, electrophysiological parameters and adverse clinical - events, suggesting prognostic importance. -FAU - Mavrogeni, Sophie -AU - Mavrogeni S -AD - Onassis Cardiac Surgery Center, 50 Esperou Street, P. Faliro, Athens 175-61 - Greece. soma13@otenet.gr -FAU - Petrou, Emmanouil -AU - Petrou E -FAU - Kolovou, Genovefa -AU - Kolovou G -FAU - Theodorakis, George -AU - Theodorakis G -FAU - Iliodromitis, Efstathios -AU - Iliodromitis E -LA - eng -PT - Journal Article -PT - Review -DEP - 20130116 -PL - England -TA - Eur Heart J Cardiovasc Imaging -JT - European heart journal. Cardiovascular Imaging -JID - 101573788 -RN - AU0V1LM3JT (Gadolinium) -SB - IM -MH - Cardiomyopathy, Hypertrophic/complications/*diagnosis -MH - Death, Sudden, Cardiac/*etiology -MH - Female -MH - Gadolinium -MH - Humans -MH - Image Enhancement/methods -MH - Magnetic Resonance Imaging/*methods -MH - *Magnetic Resonance Imaging, Cine -MH - Male -MH - Predictive Value of Tests -MH - Prognosis -MH - Risk Assessment -MH - Severity of Illness Index -MH - Tachycardia, Ventricular/complications/*diagnosis/*mortality -OTO - NOTNLM -OT - Cardiac magnetic resonance -OT - Sudden death -OT - Ventricular arrhythmia -EDAT- 2013/01/18 06:00 -MHDA- 2014/02/15 06:00 -CRDT- 2013/01/18 06:00 -PHST- 2013/01/18 06:00 [entrez] -PHST- 2013/01/18 06:00 [pubmed] -PHST- 2014/02/15 06:00 [medline] -AID - jes302 [pii] -AID - 10.1093/ehjci/jes302 [doi] -PST - ppublish -SO - Eur Heart J Cardiovasc Imaging. 2013 Jun;14(6):518-25. doi: 10.1093/ehjci/jes302. - Epub 2013 Jan 16. - -PMID- 23076940 -OWN - NLM -STAT- MEDLINE -DCOM- 20121116 -LR - 20250626 -IS - 1469-493X (Electronic) -IS - 1361-6137 (Linking) -VI - 10 -IP - 10 -DP - 2012 Oct 17 -TI - Antioxidants for chronic kidney disease. -PG - CD008176 -LID - 10.1002/14651858.CD008176.pub2 [doi] -LID - CD008176 -AB - BACKGROUND: Chronic kidney disease (CKD) is a significant risk factor for - premature cardiovascular disease and death. Increased oxidative stress in people - with CKD has been implicated as a potential causative factor for some - cardiovascular diseases. Antioxidant therapy may reduce cardiovascular mortality - and morbidity in people with CKD. OBJECTIVES: To examine the benefits and harms - of antioxidant therapy on mortality and cardiovascular events in people with CKD - stages 3 to 5; dialysis, and kidney transplantation patients. SEARCH METHODS: We - searched the Cochrane Renal Group's specialised register (July 2011), CENTRAL - (Issue 6, 2011), MEDLINE (from 1966) and EMBASE (from 1980). SELECTION CRITERIA: - We included all randomised controlled trials (RCTs) investigating the use of - antioxidants for people with CKD, or subsets of RCTs reporting outcomes for - participants with CKD. DATA COLLECTION AND ANALYSIS: Titles and abstracts were - screened independently by two authors who also performed data extraction using - standardised forms. Results were pooled using the random effects model and - expressed as either risk ratios (RR) or mean difference (MD) with 95% confidence - intervals (CI). MAIN RESULTS: We identified 10 studies (1979 participants) that - assessed antioxidant therapy in haemodialysis patients (two studies); kidney - transplant recipients (four studies); dialysis and non-dialysis CKD patients (one - study); and patients requiring surgery (one study). Two additional studies - reported the effect of an oral antioxidant inflammation modulator in patients - with CKD (estimated glomerular filtration rate (eGFR) 20 to 45 mL/min/1.73 m²), - and post-hoc findings from a subgroup of people with mild-to-moderate renal - insufficiency (serum creatinine ≥125 μmol/L) respectively. Interventions included - different doses of vitamin E (two studies); multiple antioxidant therapy (three - studies); co-enzyme Q (one study); acetylcysteine (one study); bardoxolone methyl - (one study); and human recombinant superoxide dismutase (two studies).Compared - with placebo, antioxidant therapy showed no clear overall effect on - cardiovascular mortality (RR 0.95, 95% CI 0.70 to 1.27; P = 0.71); all-cause - mortality (RR 0.93, 95% CI 0.76 to 1.14; P = 0.48); cardiovascular disease (RR - 0.78, 95% CI 0.52 to 1.18; P = 0.24); coronary heart disease (RR 0.71, 95% CI - 0.42 to 1.23; P = 0.22); cerebrovascular disease (RR 0.91, 95% CI 0.63 to 1.32; P - = 0.63); or peripheral vascular disease (RR 0.54, 95% CI 0.26 to 1.12; P = 0.10). - Subgroup analyses found no evidence of significant heterogeneity based on - proportions of males (P = 0.99) or diabetes (P = 0.87) for cardiovascular - disease. There was significant heterogeneity for cardiovascular disease when - studies were analysed by CKD stage (P = 0.003). Significant benefit was conferred - by antioxidant therapy for cardiovascular disease prevention in dialysis patients - (RR 0.57, 95% CI 0.41 to 0.80; P = 0.001), although no effect was observed in CKD - patients (RR 1.06, 95% CI 0.84 to 1.32; P = 0.63).Antioxidant therapy was found - to significantly reduce development of end-stage of kidney disease (ESKD) (RR - 0.50, 95% CI 0.25 to 1.00; P = 0.05); lowered serum creatinine levels (MD 1.10 - mg/dL, 95% CI 0.39 to 1.81; P = 0.003); and improved creatinine clearance (MD - 14.53 mL/min, 95% CI 1.20 to 27.86; P = 0.03). Serious adverse events were not - significantly increased by antioxidants (RR 2.26, 95% CI 0.74 to 6.95; P = - 0.15).Risk of bias was assessed for all studies. Studies that were classified as - unclear for random sequence generation or allocation concealment reported - significant benefits from antioxidant therapy (RR 0.57, 95% CI 0.41 to 0.80; P = - 0.001) compared with studies at low risk of bias (RR 1.06, 95% CI 0.84 to 1.32; P - = 0.63). AUTHORS' CONCLUSIONS: Although antioxidant therapy does not reduce the - risk of cardiovascular and all-cause death or major cardiovascular events in - people with CKD, it is possible that some benefit may be present, particularly in - those on dialysis. However, the small size and generally suboptimal quality of - the included studies highlighted the need for sufficiently powered studies to - confirm this possibility. Current evidence suggests that antioxidant therapy in - predialysis CKD patients may prevent progression to ESKD; this finding was - however based on a very small number of events. Further studies with longer - follow-up are needed for confirmation. Appropriately powered studies are needed - to reliably assess the effects of antioxidant therapy in people with CKD. -FAU - Jun, Min -AU - Jun M -AD - Renal and Metabolic Division, The George Institute for Global Health, Camperdown, - Australia. -FAU - Venkataraman, Vinod -AU - Venkataraman V -FAU - Razavian, Mona -AU - Razavian M -FAU - Cooper, Bruce -AU - Cooper B -FAU - Zoungas, Sophia -AU - Zoungas S -FAU - Ninomiya, Toshiharu -AU - Ninomiya T -FAU - Webster, Angela C -AU - Webster AC -FAU - Perkovic, Vlado -AU - Perkovic V -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20121017 -PL - England -TA - Cochrane Database Syst Rev -JT - The Cochrane database of systematic reviews -JID - 100909747 -RN - 0 (Antioxidants) -RN - AYI8EX34EU (Creatinine) -SB - IM -UIN - Cochrane Database Syst Rev. 2023 Nov 2;11:CD008176. doi: - 10.1002/14651858.CD008176.pub3. PMID: 37916745 -MH - Antioxidants/adverse effects/*therapeutic use -MH - Cardiovascular Diseases/mortality/prevention & control -MH - Chronic Disease -MH - Creatinine/blood -MH - Disease Progression -MH - Humans -MH - Kidney Diseases/blood/*drug therapy -MH - Kidney Failure, Chronic -MH - Kidney Transplantation -MH - Randomized Controlled Trials as Topic -MH - Renal Dialysis -PMC - PMC8941641 -COIS- Min Jun: none known. Vinod Venkataraman: none known. Mona Razavian: none known. - Bruce Cooper: none known. Sophia Zoungas has previously received speaker honoria - from Servier, MSD, Novartis, Novo Nordisk, Sanofi Aventis, Boehringer Ingelheim, - GSK, Pfizer, and Astra Zeneca/BMS and has previously served on external advisory - boards for MSD, Novo Nordisk, Boehringer Ingleheim, Sanofi Aventis and Astra - Zeneca/BMS. Toshiharu Ninomiya: none known. Angela C Webster: none known. Vlado - Perkovic is supported by a fellowship from the Heart Foundation of Australia and - a various grants from the Australian National Health and Medical Research - Council. He has received speakers fees from Roche, Servier and Astra Zeneca, - funding for a clinical trial from Baxter, and serves on Steering Committees for - trials funded by Johnson and Johnson, Boehringer Ingelheim, Vitae and Abbott. His - employer conducts clinical trials funded by Servier, Johnson and Johnson, Roche - and Merck. -EDAT- 2012/10/19 06:00 -MHDA- 2012/12/10 06:00 -PMCR- 2013/10/17 -CRDT- 2012/10/19 06:00 -PHST- 2012/10/19 06:00 [entrez] -PHST- 2012/10/19 06:00 [pubmed] -PHST- 2012/12/10 06:00 [medline] -PHST- 2013/10/17 00:00 [pmc-release] -AID - CD008176.pub2 [pii] -AID - 10.1002/14651858.CD008176.pub2 [doi] -PST - epublish -SO - Cochrane Database Syst Rev. 2012 Oct 17;10(10):CD008176. doi: - 10.1002/14651858.CD008176.pub2. - -PMID- 23147391 -OWN - NLM -STAT- MEDLINE -DCOM- 20130429 -LR - 20220330 -IS - 1879-0631 (Electronic) -IS - 0024-3205 (Print) -IS - 0024-3205 (Linking) -VI - 92 -IP - 11 -DP - 2013 Mar 28 -TI - Molecular and metabolic mechanisms of cardiac dysfunction in diabetes. -PG - 601-8 -LID - S0024-3205(12)00655-8 [pii] -LID - 10.1016/j.lfs.2012.10.028 [doi] -AB - Diabetes mellitus type 2 (T2DM) is a widespread chronic medical condition with - prevalence bordering on the verge of an epidemic. It is of great concern that - cardiovascular disease is more common in patients with diabetes than the - non-diabetic population. While hypertensive and ischemic heart disease is more - common in diabetic patients, there is another type of heart disease in diabetes - that is not associated with hypertension or coronary artery disease. This muscle - functional disorder is termed "diabetic cardiomyopathy". Diastolic dysfunction - characterized by impaired diastolic relaxation time and reduced contractility - precedes systolic dysfunction and is the main pathogenic hallmark of this - condition. Even though the pathogenesis of "diabetic cardiomyopathy" is still - controversial, impaired cardiac insulin sensitivity and metabolic overload are - emerging as major molecular and metabolic mechanisms for cardiac dysfunction. - Systemic insulin resistance, hyperinsulinemia, dysregulation of adipokine - secretion, increases in circulating levels of inflammatory mediators, aberrant - activation of renin angiotensin aldosterone system (RAAS), and increased - oxidative stress contribute dysregulated insulin and metabolic signaling in the - heart and development of diastolic dysfunction. In addition, maladaptive calcium - homeostasis and endothelial cell dysregulation endoplasmic reticular stress play - a potential role in cardiomyocyte fibrosis/diastolic dysfunction. In this review, - we will focus on emerging molecular and metabolic pathways underlying cardiac - dysfunction in diabetes. Elucidation of these mechanisms should provide a better - understanding of the various cardiac abnormalities associated with diastolic - dysfunction and its progression to systolic dysfunction and heart failure. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Mandavia, Chirag H -AU - Mandavia CH -AD - University of Missouri School of Medicine, Department of Internal Medicine, - Columbia, MO, USA. -FAU - Aroor, Annayya R -AU - Aroor AR -FAU - Demarco, Vincent G -AU - Demarco VG -FAU - Sowers, James R -AU - Sowers JR -LA - eng -GR - R01 HL073101/HL/NHLBI NIH HHS/United States -GR - R01 HL107910/HL/NHLBI NIH HHS/United States -GR - R01 HL107910-01/HL/NHLBI NIH HHS/United States -GR - R01 HL73101-01A/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -DEP - 20121109 -PL - Netherlands -TA - Life Sci -JT - Life sciences -JID - 0375521 -SB - IM -MH - Cardio-Renal Syndrome/etiology/genetics/physiopathology -MH - Diabetes Mellitus, Type 2/*complications/genetics/*physiopathology -MH - Diabetic Cardiomyopathies/*etiology/genetics/*physiopathology -MH - Humans -MH - Oxidative Stress -MH - Signal Transduction -PMC - PMC3594135 -MID - NIHMS421512 -EDAT- 2012/11/14 06:00 -MHDA- 2013/04/30 06:00 -PMCR- 2014/03/28 -CRDT- 2012/11/14 06:00 -PHST- 2012/05/04 00:00 [received] -PHST- 2012/10/17 00:00 [revised] -PHST- 2012/10/22 00:00 [accepted] -PHST- 2012/11/14 06:00 [entrez] -PHST- 2012/11/14 06:00 [pubmed] -PHST- 2013/04/30 06:00 [medline] -PHST- 2014/03/28 00:00 [pmc-release] -AID - S0024-3205(12)00655-8 [pii] -AID - 10.1016/j.lfs.2012.10.028 [doi] -PST - ppublish -SO - Life Sci. 2013 Mar 28;92(11):601-8. doi: 10.1016/j.lfs.2012.10.028. Epub 2012 Nov - 9. - -PMID- 19860299 -OWN - NLM -STAT- MEDLINE -DCOM- 20091202 -LR - 20190608 -IS - 0027-9684 (Print) -IS - 0027-9684 (Linking) -VI - 101 -IP - 10 -DP - 2009 Oct -TI - Peripheral arterial disease: considerations in risks, diagnosis, and treatment. -PG - 999-1008 -AB - Peripheral arterial disease (PAD), a manifestation of systemic atherosclerosis, - is a marker for coronary artery, cerebrovascular, and renal artery - atherosclerotic vascular disease. Patients with PAD have an increased risk of - cardiovascular events such as myocardial infarction and stroke in addition to - significant impairment in their quality of life and physical function. Early - detection and implementation of guideline-recommended therapies are paramount to - effective treatment of PAD. Measurement of the ankle-brachial index is a simple, - reliable, and noninvasive test to diagnose PAD that can be used in a primary care - setting. Lifestyle modification, including exercise and smoking cessation, - combined with pharmacologic therapy to manage risk factors have been shown - effective in reducing cardiovascular risks in patients with PAD. Evidence - suggests, however, that there is currently a lack of awareness regarding PAD - among physicians and patients, leading to underdiagnosis and undertreatment. This - paper reviews the epidemiology, pathology, and clinical implications of PAD, and - offers current evidence for disease management quality improvement initiatives to - enhance patient care. -FAU - Mukherjee, Debabrata -AU - Mukherjee D -AD - Gill Heart Institute, Division of Cardiovascular Medicine, University of - Kentucky, 900 S Limestone St. 326 Wethington Bad, Lexington, Kentucky 40536-0200, - USA. dmukh2@email.uky.edu -FAU - Cho, Leslie -AU - Cho L -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Natl Med Assoc -JT - Journal of the National Medical Association -JID - 7503090 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Ankle Brachial Index -MH - Atherosclerosis/physiopathology -MH - Comorbidity -MH - Humans -MH - Hypertension/epidemiology -MH - Life Style -MH - *Peripheral Vascular Diseases/diagnosis/epidemiology/therapy -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Prevalence -MH - Risk Factors -MH - Risk Reduction Behavior -RF - 57 -EDAT- 2009/10/29 06:00 -MHDA- 2009/12/16 06:00 -CRDT- 2009/10/29 06:00 -PHST- 2009/10/29 06:00 [entrez] -PHST- 2009/10/29 06:00 [pubmed] -PHST- 2009/12/16 06:00 [medline] -AID - S0027-9684(15)31066-X [pii] -AID - 10.1016/s0027-9684(15)31066-x [doi] -PST - ppublish -SO - J Natl Med Assoc. 2009 Oct;101(10):999-1008. doi: 10.1016/s0027-9684(15)31066-x. - -PMID- 18714616 -OWN - NLM -STAT- MEDLINE -DCOM- 20081218 -LR - 20190319 -IS - 0310-057X (Print) -IS - 0310-057X (Linking) -VI - 36 -IP - 4 -DP - 2008 Jul -TI - Heart rate and outcome in patients with cardiovascular disease undergoing major - noncardiac surgery. -PG - 489-501 -AB - There is an increasing awareness that an elevated resting heart rate is - associated with increased all-cause mortality in the general population and that - this may be an independent coronary risk factor This review was undertaken to - determine whether heart rate is predictive of increased mortality and major - morbidity in noncardiac surgical patients and whether heart rate manipulation - improves perioperative outcome. A search of Medline from 1966 until October 2007 - was conducted using the terms "heart rate", "surgery", "cardiac", "morbidity", - "mortality" and "perioperative". The main findings were that an elevated - perioperative heart rate, an absolute increase in heart rate and heart rate - lability are independent predictors of both short- and long-term adverse outcomes - in patients at cardiovascular risk undergoing major noncardiac surgery. Although - prospective nonrandomised and retrospective data suggest heart rate control - improves perioperative outcome, there is conflicting evidence from randomised - trials that perioperative heart rate control improves outcome. This may be - because drug-associated bradycardia influences mortality in the perioperative - period. Further studies reporting the absolute heart rate, the absolute change of - heart rate and the time period of the observations are needed to identify 'early - warning systems', which may allow earlier triage and improved outcome. Enthusiasm - for this approach must be tempered by the appreciation that a J-shaped - relationship probably exists between heart rate and morbidity, particularly - following bradycardic therapy. Therefore, any bradycardic manipulation of heart - rate in the perioperative period must be accompanied by simultaneous attention to - other physiological variables associated with increased morbidity and mortality. -FAU - Biccard, B M -AU - Biccard BM -AD - Department of Anaesthetics, Nelson R. Mandela School of Medicine, Congella, South - Africa. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Anaesth Intensive Care -JT - Anaesthesia and intensive care -JID - 0342017 -RN - 0 (Adrenergic beta-Antagonists) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Age Factors -MH - Cardiovascular Diseases/*physiopathology -MH - Heart Rate/*physiology -MH - Hospital Mortality -MH - Monitoring, Intraoperative/methods -MH - Myocardial Ischemia/diagnosis/drug therapy/physiopathology -MH - Prognosis -MH - Surgical Procedures, Operative/adverse effects/*mortality -MH - Treatment Outcome -RF - 88 -EDAT- 2008/08/22 09:00 -MHDA- 2008/12/19 09:00 -CRDT- 2008/08/22 09:00 -PHST- 2008/08/22 09:00 [pubmed] -PHST- 2008/12/19 09:00 [medline] -PHST- 2008/08/22 09:00 [entrez] -AID - 20080097 [pii] -AID - 10.1177/0310057X0803600403 [doi] -PST - ppublish -SO - Anaesth Intensive Care. 2008 Jul;36(4):489-501. doi: 10.1177/0310057X0803600403. - -PMID- 21269265 -OWN - NLM -STAT- MEDLINE -DCOM- 20110901 -LR - 20201209 -IS - 1873-5592 (Electronic) -IS - 1389-4501 (Linking) -VI - 12 -IP - 6 -DP - 2011 Jun -TI - Mitochondria as a target for exercise-induced cardioprotection. -PG - 860-71 -AB - Cardiac damage is a major contributor to the morbidity and mortality particularly - associated with coronary artery disease. Moreover, it is also related to some - metabolic diseases such as diabetes and to some side effects of drug treatments. - Regular exercise has been confirmed as a pragmatic countermeasure to protect - against cardiac injury. Specifically, life-long physical activity and endurance - exercise training have been proven to provide cardioprotection against cardiac - insults in both young and old animals. It is suggested that the beneficial - effects resulting from increased physical activity levels occur at different - levels of cellular organization, being mitochondria preferential target - organelles. At present, it remains unclear what the protective mechanisms that - are essential for exercise-induced cardioprotection are. Proposed mechanisms to - explain the cardioprotective effects of exercise are mediated, at least - partially, by redox changes and include the up-regulation of mitochondrial - chaperones, improved antioxidant capacity, and/or elevation of other protective - molecules against cellular death. It is possible that under some conditions, - exercise also diminishes the increased susceptibility of cardiac mitochondria to - undergo permeability transition pore opening through the modulation of pore - components or sensitizers. The role of physical exercise against the impairment - of heart mitochondrial function that accompany ageing, diabetes, administration - of the anti-cancer agent Doxorubicin and ischemia-reperfusion is analysed in the - present review, which provides biochemical, functional and morphological data - illustrating the cross tolerance effect of exercise in these conditions - predisposing to cardiac "mitotoxicity". However, further work should be addressed - in order to clarify the precise regulatory mechanisms by which physical exercise - augments heart mitochondrial tolerance against many conditions predisposing to - dysfunction. -FAU - Ascensão, António -AU - Ascensão A -AD - Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, - University of Porto, Portugal. aascensao@fade.up.pt -FAU - Lumini-Oliveira, José -AU - Lumini-Oliveira J -FAU - Oliveira, Paulo J -AU - Oliveira PJ -FAU - Magalhães, José -AU - Magalhães J -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Drug Targets -JT - Current drug targets -JID - 100960531 -RN - 0 (Mitochondrial Membrane Transport Proteins) -RN - 0 (Mitochondrial Permeability Transition Pore) -SB - IM -MH - Age Factors -MH - Aging -MH - Animals -MH - Cardiovascular Diseases/etiology/*physiopathology -MH - Exercise/*physiology -MH - Humans -MH - Mitochondria, Heart/*metabolism -MH - Mitochondrial Membrane Transport Proteins/metabolism -MH - Mitochondrial Permeability Transition Pore -MH - Oxidation-Reduction -MH - Physical Endurance -EDAT- 2011/01/29 06:00 -MHDA- 2011/09/02 06:00 -CRDT- 2011/01/29 06:00 -PHST- 2010/02/02 00:00 [received] -PHST- 2010/07/03 00:00 [accepted] -PHST- 2011/01/29 06:00 [entrez] -PHST- 2011/01/29 06:00 [pubmed] -PHST- 2011/09/02 06:00 [medline] -AID - BSP/CDT/E-Pub/00231 [pii] -AID - 10.2174/138945011795529001 [doi] -PST - ppublish -SO - Curr Drug Targets. 2011 Jun;12(6):860-71. doi: 10.2174/138945011795529001. - -PMID- 21900319 -OWN - NLM -STAT- MEDLINE -DCOM- 20120827 -LR - 20211020 -IS - 1742-5662 (Electronic) -IS - 1742-5689 (Print) -IS - 1742-5662 (Linking) -VI - 9 -IP - 66 -DP - 2012 Jan 7 -TI - Biomaterial strategies for alleviation of myocardial infarction. -PG - 1-19 -LID - 10.1098/rsif.2011.0301 [doi] -AB - World Health Organization estimated that heart failure initiated by coronary - artery disease and myocardial infarction (MI) leads to 29 per cent of deaths - worldwide. Heart failure is one of the leading causes of death in industrialized - countries and is expected to become a global epidemic within the twenty-first - century. MI, the main cause of heart failure, leads to a loss of cardiac tissue - impairment of left ventricular function. The damaged left ventricle undergoes - progressive 'remodelling' and chamber dilation, with myocyte slippage and - fibroblast proliferation. Repair of diseased myocardium with in vitro-engineered - cardiac muscle patch/injectable biopolymers with cells may become a viable option - for heart failure patients. These events reflect an apparent lack of effective - intrinsic mechanism for myocardial repair and regeneration. Motivated by the - desire to develop minimally invasive procedures, the last 10 years observed - growing efforts to develop injectable biomaterials with and without cells to - treat cardiac failure. Biomaterials evaluated include alginate, fibrin, collagen, - chitosan, self-assembling peptides, biopolymers and a range of synthetic - hydrogels. The ultimate goal in therapeutic cardiac tissue engineering is to - generate biocompatible, non-immunogenic heart muscle with morphological and - functional properties similar to natural myocardium to repair MI. This review - summarizes the properties of biomaterial substrates having sufficient mechanical - stability, which stimulates the native collagen fibril structure for - differentiating pluripotent stem cells and mesenchymal stem cells into - cardiomyocytes for cardiac tissue engineering. -FAU - Venugopal, Jayarama Reddy -AU - Venugopal JR -AD - Healthcare and Energy Materials Laboratory, Nanoscience and Nanotechnology - Initiative, Faculty of Engineering, National University of Singapore, Singapore. - nnijrv@nus.edu.sg -FAU - Prabhakaran, Molamma P -AU - Prabhakaran MP -FAU - Mukherjee, Shayanti -AU - Mukherjee S -FAU - Ravichandran, Rajeswari -AU - Ravichandran R -FAU - Dan, Kai -AU - Dan K -FAU - Ramakrishna, Seeram -AU - Ramakrishna S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110907 -PL - England -TA - J R Soc Interface -JT - Journal of the Royal Society, Interface -JID - 101217269 -RN - 0 (Biocompatible Materials) -SB - IM -MH - Adipose Tissue/cytology -MH - Animals -MH - Biocompatible Materials/*therapeutic use -MH - Biomechanical Phenomena -MH - Cell Differentiation -MH - Cord Blood Stem Cell Transplantation -MH - Extracellular Matrix/metabolism -MH - Mesenchymal Stem Cells/cytology -MH - Myocardial Infarction/*therapy -MH - Myocardium/cytology -MH - Pluripotent Stem Cells/cytology -MH - Rats -MH - Tissue Engineering/trends -MH - Tissue Scaffolds/chemistry -PMC - PMC3223634 -EDAT- 2011/09/09 06:00 -MHDA- 2012/08/28 06:00 -PMCR- 2011/04/13 -CRDT- 2011/09/09 06:00 -PHST- 2011/09/09 06:00 [entrez] -PHST- 2011/09/09 06:00 [pubmed] -PHST- 2012/08/28 06:00 [medline] -PHST- 2011/04/13 00:00 [pmc-release] -AID - rsif.2011.0301 [pii] -AID - rsif20110301 [pii] -AID - 10.1098/rsif.2011.0301 [doi] -PST - ppublish -SO - J R Soc Interface. 2012 Jan 7;9(66):1-19. doi: 10.1098/rsif.2011.0301. Epub 2011 - Sep 7. - -PMID- 21892746 -OWN - NLM -STAT- MEDLINE -DCOM- 20120327 -LR - 20241219 -IS - 1435-1803 (Electronic) -IS - 0300-8428 (Linking) -VI - 106 -IP - 6 -DP - 2011 Nov -TI - The potential effects of anti-diabetic medications on myocardial - ischemia-reperfusion injury. -PG - 925-52 -LID - 10.1007/s00395-011-0216-6 [doi] -AB - Heart disease and stroke account for 65% of the deaths in people with diabetes - mellitus (DM). DM and hyperglycemia cause systemic inflammation, endothelial - dysfunction, a hypercoagulable state with impaired fibrinolysis and increased - platelet degranulation, and reduced coronary collateral blood flow. DM also - interferes with myocardial protection afforded by preconditioning and - postconditioning. Newer anti-diabetic agents should not only reduce serum glucose - and HbA1c levels, but also improve cardiovascular outcomes. The older - sulfonylurea agent, glyburide, abolishes the benefits of ischemic and - pharmacologic preconditioning, but newer sulfonylurea agents, such as - glimepiride, may not interfere with preconditioning. GLP-1 analogs and - sitagliptin, an oral dipeptidyl peptidase IV inhibitor, limit myocardial infarct - size in animal models by increasing intracellular cAMP levels and activating - protein kinase A, whereas metformin protects the heart by activating - AMP-activated protein kinase. Both thiazolidinediones (rosiglitazone and - pioglitazone) limit infarct size in animal models. The protective effect of - pioglitazone is dependent on downstream activation of cytosolic phospholipase - A(2) and cyclooxygenase-2 with subsequent increased production of 15-epi-lipoxin - A(4), prostacyclin and 15-d-PGJ(2). We conclude that agents used to treat DM have - additional actions that have been shown to affect the ability of the heart to - protect itself against ischemia-reperfusion injury in preclinical models. - However, the effects of these agents in doses used in the clinical setting to - minimize ischemia-reperfusion injury and to affect clinical outcomes in patients - with DM have yet to be shown. The clinical implications as well as the mechanisms - of protection should be further studied. -FAU - Ye, Yumei -AU - Ye Y -AD - Department of Biochemistry and Molecular Biology, University of Texas Medical - Branch, Galveston, TX, USA. -FAU - Perez-Polo, Jose R -AU - Perez-Polo JR -FAU - Aguilar, David -AU - Aguilar D -FAU - Birnbaum, Yochai -AU - Birnbaum Y -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110904 -PL - Germany -TA - Basic Res Cardiol -JT - Basic research in cardiology -JID - 0360342 -RN - 0 (Hypoglycemic Agents) -SB - IM -MH - Animals -MH - Diabetes Mellitus/drug therapy -MH - Heart/*drug effects -MH - Humans -MH - Hypoglycemic Agents/*pharmacology -MH - Myocardial Reperfusion Injury/*physiopathology/*prevention & control -EDAT- 2011/09/06 06:00 -MHDA- 2012/03/28 06:00 -CRDT- 2011/09/06 06:00 -PHST- 2011/05/02 00:00 [received] -PHST- 2011/08/16 00:00 [accepted] -PHST- 2011/08/04 00:00 [revised] -PHST- 2011/09/06 06:00 [entrez] -PHST- 2011/09/06 06:00 [pubmed] -PHST- 2012/03/28 06:00 [medline] -AID - 10.1007/s00395-011-0216-6 [doi] -PST - ppublish -SO - Basic Res Cardiol. 2011 Nov;106(6):925-52. doi: 10.1007/s00395-011-0216-6. Epub - 2011 Sep 4. - -PMID- 19017008 -OWN - NLM -STAT- MEDLINE -DCOM- 20090401 -LR - 20081121 -IS - 1540-8191 (Electronic) -IS - 0886-0440 (Linking) -VI - 23 -IP - 6 -DP - 2008 Nov-Dec -TI - Cardiac and great vessel involvement in "Behcet's disease". -PG - 765-8 -LID - 10.1111/j.1540-8191.2008.00607.x [doi] -AB - Behcet's disease is a multisystem disorder and classified as "vasculitic syndrome - with a wide variety of clinical manifestations." Cardiac involvement is very rare - but can occur with different presentations including: pericarditis, - cardiomyopathy, endocarditis, endomyocardial fibrosis, intracavitary thrombosis, - and coronary artery disease. Great vessel involvement is more common. Recurrent - Phlebitis, commonly involving large vessels (superior vena cava, inferior vena - cava, hepatic veins) and cerebral veins are the sole presentation in this regard. - Arterial involvement is expressed by aneurysm or pseudoaneurysmal formation. Due - to the wide variety of cardiovascular manifestations and the resulting high - mortality, cardiac surgeons should be familiar with this disease. In this paper - we review the articles and introduce our four cases presenting with aneurysm of - ascending aorta with free aortic insufficiency, aneurysm of descending aorta, - pulmonary artery aneurysm, and pseudoaneurysm of aortic arch. -FAU - Marzban, Mehrab -AU - Marzban M -AD - Tehran Heart Center, Medical Sciences, University of Tehran, Tehran, Iran. - mehrabmarzban2007@yahoo.com -FAU - Mandegar, Mohammad Hossein -AU - Mandegar MH -FAU - Karimi, Abbasali -AU - Karimi A -FAU - Abbasi, Kyomars -AU - Abbasi K -FAU - Movahedi, Namvar -AU - Movahedi N -FAU - Navabi, Mohammad Ali -AU - Navabi MA -FAU - Abbasi, Seyed Hesameddin -AU - Abbasi SH -FAU - Moshtaghi, Naghmeh -AU - Moshtaghi N -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - J Card Surg -JT - Journal of cardiac surgery -JID - 8908809 -SB - IM -MH - Adult -MH - Aneurysm/*etiology/surgery -MH - Aneurysm, False/pathology/surgery -MH - Aortic Aneurysm/etiology -MH - Aortic Aneurysm, Abdominal/etiology -MH - Aortic Aneurysm, Thoracic/etiology -MH - Behcet Syndrome/*complications/diagnosis/physiopathology/surgery -MH - Cardiac Surgical Procedures -MH - Cardiovascular Diseases/*etiology/mortality/surgery -MH - Fatal Outcome -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Pulmonary Artery/pathology -RF - 23 -EDAT- 2008/11/20 09:00 -MHDA- 2009/04/02 09:00 -CRDT- 2008/11/20 09:00 -PHST- 2008/11/20 09:00 [pubmed] -PHST- 2009/04/02 09:00 [medline] -PHST- 2008/11/20 09:00 [entrez] -AID - JCS607 [pii] -AID - 10.1111/j.1540-8191.2008.00607.x [doi] -PST - ppublish -SO - J Card Surg. 2008 Nov-Dec;23(6):765-8. doi: 10.1111/j.1540-8191.2008.00607.x. - -PMID- 20616737 -OWN - NLM -STAT- MEDLINE -DCOM- 20101104 -LR - 20221207 -IS - 1531-6963 (Electronic) -IS - 1040-8711 (Linking) -VI - 22 -IP - 5 -DP - 2010 Sep -TI - Kawasaki disease: update on pathogenesis. -PG - 551-60 -LID - 10.1097/BOR.0b013e32833cf051 [doi] -AB - PURPOSE OF REVIEW: This review will highlight recent advances in our - understanding of the pathogenesis of Kawasaki disease, highlighting the molecular - players involved in regulation of T-cell activation and their affect on disease - incidence and outcome in both humans and mouse. RECENT FINDINGS: Kawasaki disease - is the most common cause of multisystem vasculitis in childhood. The vessels most - commonly damaged are the coronary arteries, making Kawasaki disease the number - one cause of acquired heart disease in children from the developed world. The - contribution of genetics to disease predisposition is clearly implicated, but the - mechanisms involved in regulating predisposition to disease susceptibility and - outcome are not clearly understood. Two independent approaches have recently - identified regulation of T-cell activation as the critical factor in determining - susceptibility and severity of Kawasaki disease. Firstly, genetic analysis of - affected Japanese children identified ITPKC, 1,4,5-triphosphate 3-kinase C, a - kinase involved in regulation of T-cell activation, to be significantly - associated with susceptibility to and increased severity of Kawasaki disease. A - second independent approach using an animal model of Kawasaki disease has also - identified regulation of T-cell activation, specifically costimulation, the - second signal regulating optimal T-cell activation as the critical regulator of - susceptibility to and severity of disease. SUMMARY: Understanding the molecular - players responsible for dysregulation of the immune response in Kawasaki disease - will foster development of improved diagnostic/predictive tools and more rational - use of therapeutic agents to improve outcome in affected children. -FAU - Yeung, Rae S M -AU - Yeung RS -AD - Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada. - rae.yeung@sickkids.ca -LA - eng -GR - MOP-81378/Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Opin Rheumatol -JT - Current opinion in rheumatology -JID - 9000851 -RN - EC 2.7.1.- (Phosphotransferases (Alcohol Group Acceptor)) -RN - EC 2.7.1.127 (Inositol 1,4,5-trisphosphate 3-kinase) -SB - IM -MH - Asian People/genetics -MH - Child -MH - Genetic Predisposition to Disease -MH - Humans -MH - Mucocutaneous Lymph Node Syndrome/*etiology/genetics/immunology -MH - Phosphotransferases (Alcohol Group Acceptor)/genetics -MH - T-Lymphocytes/*immunology -EDAT- 2010/07/10 06:00 -MHDA- 2010/11/05 06:00 -CRDT- 2010/07/10 06:00 -PHST- 2010/07/10 06:00 [entrez] -PHST- 2010/07/10 06:00 [pubmed] -PHST- 2010/11/05 06:00 [medline] -AID - 10.1097/BOR.0b013e32833cf051 [doi] -PST - ppublish -SO - Curr Opin Rheumatol. 2010 Sep;22(5):551-60. doi: 10.1097/BOR.0b013e32833cf051. - -PMID- 20005474 -OWN - NLM -STAT- MEDLINE -DCOM- 20100203 -LR - 20181201 -IS - 1873-2615 (Electronic) -IS - 1050-1738 (Linking) -VI - 19 -IP - 5 -DP - 2009 Jul -TI - Heart rate reduction by I(f)-channel inhibition and its potential role in heart - failure with reduced and preserved ejection fraction. -PG - 152-7 -LID - 10.1016/j.tcm.2009.09.002 [doi] -AB - Selective heart rate (HR) reduction by I(f)-channel inhibition is a recently - developed pharmacological principle in cardiovascular therapy. Among these newly - identified HR-lowering drugs, only ivabradine has now become approved for - clinical use. I(f)-channel inhibition mainly reduces HR, thereby improving - myocardial oxygen supply, energy balance, and cardiac function. Ivabradine was - well tolerated and revealed a good safety profile in the investigated study - populations. The guiding experimental and clinical results of I(f)-channel - inhibition were compared to those of beta-blockade as a HR reducing principle as - well as cornerstone of heart failure standard therapy. Beside its use in therapy - of coronary artery disease, I(f)-channel inhibition potentially exhibits - beneficial effects in systolic and diastolic heart failure as well. Therefore, - hemodynamic effects of ivabradine and its limitations in heart failure together - with the biological impact of HR reduction will be considered in this context. - Because no clinical data with specific heart-rate-reducing agents are available - in heart failure patients until now, the prospective significance of I(f)-channel - inhibition can only be speculated on. However, the presented results and - considerations are encouraging: ivabradine may play a therapeutic role in the - future protecting left ventricular function and structure from early - deterioration in heart failure with reduced and preserved ventricular ejection - fraction. -FAU - Reil, Jan-Christian -AU - Reil JC -AD - Klinik für Innere Medizin III, University of the Saarland, Homburg Saar, Germany. - reil@med-in.uni-saarland.de -FAU - Reil, Gert-Hinrich -AU - Reil GH -FAU - Böhm, Michael -AU - Böhm M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Trends Cardiovasc Med -JT - Trends in cardiovascular medicine -JID - 9108337 -RN - 0 (Benzazepines) -RN - 0 (Cardiotonic Agents) -RN - 3H48L0LPZQ (Ivabradine) -SB - IM -MH - Benzazepines/pharmacology/*therapeutic use -MH - Cardiotonic Agents/pharmacology/*therapeutic use -MH - Heart Failure/*drug therapy/physiopathology -MH - Heart Rate/*drug effects -MH - Hemodynamics/drug effects -MH - Humans -MH - Ivabradine -MH - Stroke Volume/*drug effects -MH - Treatment Outcome -MH - Ventricular Dysfunction, Left/drug therapy/physiopathology -MH - Ventricular Function, Left/drug effects -RF - 43 -EDAT- 2009/12/17 06:00 -MHDA- 2010/02/04 06:00 -CRDT- 2009/12/17 06:00 -PHST- 2009/12/17 06:00 [entrez] -PHST- 2009/12/17 06:00 [pubmed] -PHST- 2010/02/04 06:00 [medline] -AID - S1050-1738(09)00144-3 [pii] -AID - 10.1016/j.tcm.2009.09.002 [doi] -PST - ppublish -SO - Trends Cardiovasc Med. 2009 Jul;19(5):152-7. doi: 10.1016/j.tcm.2009.09.002. - -PMID- 19486852 -OWN - NLM -STAT- MEDLINE -DCOM- 20090908 -LR - 20220331 -IS - 1532-6578 (Electronic) -IS - 1062-0303 (Linking) -VI - 27 -IP - 2 -DP - 2009 Jun -TI - Peripheral arterial disease: Pathophysiology, risk factors, diagnosis, treatment, - and prevention. -PG - 26-30 -LID - 10.1016/j.jvn.2009.03.001 [doi] -AB - Peripheral Artery Disease (PAD) is a strong predictor of MI, stroke and death due - to vascular causes. PAD affects 8-12 million people in the United States. As the - population lives longer with chronic diseases, researchers estimate that the - incidence of PAD will increase, likely increasing myocardial infarction, stroke - and death. This paper reviews the epidemiology, pathophysiology, risk factors, - treatment and management of PAD. With improved understanding of the disease - process, risk factors and treatment, clinicians will be able to detect PAD - earlier, provide diagnosis, treat and manage this disease. PAD is associated with - reduced quality of life, and persons with PAD are also at risk of developing - coronary artery disease and cerebrovascular disease. Better clinical evaluation - and routine screening are important in identifying and treating patients at risk - for PAD. All patients with PAD should receive risk-factor modification, such as - treatment and education, about smoking cessation, blood pressure control and - lowering of cholesterol. Appropriate pharmacological management includes - antiplatelet therapy of aspirin, use of clopidogrel for those individuals who are - sensitive to aspirin. Patients who have had bypass surgery or stent placement - require dual antiplatelet therapy of aspirin and clopidogrel. The American Heart - Association (AHA) states that treatment with beta-blockers and ACE inhibitors is - appropriate pharmacotherapy to treat PAD. Other FDA approved medications such as - Cilostazol and Pentoxifylline are also used in the treatment of pain associated - with intermittent claudication. -FAU - Muir, Rachelle L -AU - Muir RL -AD - University of Michigan, Flint, 303 Kearsley, Flint, Michigan, USA. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Vasc Nurs -JT - Journal of vascular nursing : official publication of the Society for Peripheral - Vascular Nursing -JID - 9014475 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Blood Vessel Prosthesis Implantation -MH - Cause of Death -MH - Humans -MH - Incidence -MH - Myocardial Infarction/epidemiology/etiology -MH - *Peripheral Vascular Diseases/diagnosis/epidemiology/etiology/therapy -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Primary Prevention -MH - Quality of Life -MH - Risk Factors -MH - Risk Reduction Behavior -MH - Stroke/epidemiology/etiology -MH - United States/epidemiology -RF - 17 -EDAT- 2009/06/03 09:00 -MHDA- 2009/09/09 06:00 -CRDT- 2009/06/03 09:00 -PHST- 2009/06/03 09:00 [entrez] -PHST- 2009/06/03 09:00 [pubmed] -PHST- 2009/09/09 06:00 [medline] -AID - S1062-0303(09)00027-2 [pii] -AID - 10.1016/j.jvn.2009.03.001 [doi] -PST - ppublish -SO - J Vasc Nurs. 2009 Jun;27(2):26-30. doi: 10.1016/j.jvn.2009.03.001. - -PMID- 22895924 -OWN - NLM -STAT- MEDLINE -DCOM- 20120926 -LR - 20250626 -IS - 1469-493X (Electronic) -IS - 1361-6137 (Linking) -IP - 8 -DP - 2012 Aug 15 -TI - Beta-blockers for hypertension. -PG - CD002003 -LID - 10.1002/14651858.CD002003.pub3 [doi] -AB - BACKGROUND: This review is an update of the Cochrane Review published in 2007, - which assessed the role of beta-blockade as first-line therapy for hypertension. - OBJECTIVES: To quantify the effectiveness and safety of beta-blockers on - morbidity and mortality endpoints in adults with hypertension. SEARCH METHODS: In - December 2011 we searched the Cochrane Central Register of Controlled Trials, - Medline, Embase, and reference lists of previous reviews; for eligible studies - published since the previous search we conducted in May 2006. SELECTION CRITERIA: - Randomised controlled trials (RCTs) of at least one year duration, which assessed - the effects of beta-blockers compared to placebo or other drugs, as first-line - therapy for hypertension, on mortality and morbidity in adults. DATA COLLECTION - AND ANALYSIS: We selected studies and extracted data in duplicate. We expressed - study results as risk ratios (RR) with 95% confidence intervals (CI) and combined - them using the fixed-effects or random-effects method, as appropriate. MAIN - RESULTS: We included 13 RCTs which compared beta-blockers to placebo (4 trials, - N=23,613), diuretics (5 trials, N=18,241), calcium-channel blockers (CCBs: 4 - trials, N=44,825), and renin-angiotensin system (RAS) inhibitors (3 trials, - N=10,828). Three-quarters of the 40,245 participants on beta-blockers used - atenolol. Most studies had a high risk of bias; resulting from various - limitations in study design, conduct, and data analysis.Total mortality was not - significantly different between beta-blockers and placebo (RR 0.99, 95%CI 0.88 to - 1.11; I(2)=0%), diuretics or RAS inhibitors, but was higher for beta-blockers - compared to CCBs (RR 1.07, 95%CI 1.00 to 1.14; I(2)=2%). Total cardiovascular - disease (CVD) was lower for beta-blockers compared to placebo (RR 0.88, 95%CI - 0.79 to 0.97; I(2)=21%). This is primarily a reflection of the significant - decrease in stroke (RR 0.80, 95%CI 0.66 to 0.96; I(2)=0%), since there was no - significant difference in coronary heart disease (CHD) between beta-blockers and - placebo. There was no significant difference in withdrawals from assigned - treatment due to adverse events between beta-blockers and placebo (RR 1.12, 95%CI - 0.82 to 1.54; I(2)=66%).The effect of beta-blockers on CVD was significantly - worse than that of CCBs (RR 1.18, 95%CI 1.08-1.29; I(2)=0%), but was not - different from that of diuretics or RAS inhibitors. In addition, there was an - increase in stroke in beta-blockers compared to CCBs (RR 1.24, 95%CI 1.11-1.40; - I(2)=0%) and RAS inhibitors (RR 1.30, 95%CI 1.11 to 1.53; I(2)=29%). However, CHD - was not significantly different between beta-blockers and diuretics, CCBs or RAS - inhibitors. Participants on beta-blockers were more likely to discontinue - treatment due to adverse events than those on RAS inhibitors (RR 1.41, 95% CI - 1.29 to 1.54; I(2)=12%), but there was no significant difference with diuretics - or CCBs. AUTHORS' CONCLUSIONS: Initiating treatment of hypertension with - beta-blockers leads to modest reductions in cardiovascular disease and no - significant effects on mortality. These effects of beta-blockers are inferior to - those of other antihypertensive drugs. The GRADE quality of this evidence is low, - implying that the true effect of beta-blockers may be substantially different - from the estimate of effects found in this review. Further research should be of - high quality and should explore whether there are differences between different - sub-types of beta-blockers or whether beta-blockers have differential effects on - younger and elderly patients. -FAU - Wiysonge, Charles Shey -AU - Wiysonge CS -AD - Institute of Infectious Disease and Molecular Medicine & Division of Medical - Microbiology, University of Cape Town, Anzio Road, Observatory, South Africa, - 7925. -FAU - Bradley, Hazel A -AU - Bradley HA -FAU - Volmink, Jimmy -AU - Volmink J -FAU - Mayosi, Bongani M -AU - Mayosi BM -FAU - Mbewu, Anthony -AU - Mbewu A -FAU - Opie, Lionel H -AU - Opie LH -LA - eng -GR - Wellcome Trust/United Kingdom -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20120815 -PL - England -TA - Cochrane Database Syst Rev -JT - The Cochrane database of systematic reviews -JID - 100909747 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin Receptor Antagonists) -RN - 0 (Antihypertensive Agents) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Diuretics) -SB - IM -UOF - Cochrane Database Syst Rev. 2007 Jan 24;(1):CD002003. doi: - 10.1002/14651858.CD002003.pub2. PMID: 17253471 -UIN - Cochrane Database Syst Rev. 2012 Nov 14;11:CD002003. doi: - 10.1002/14651858.CD002003.pub4. PMID: 23152211 -CIN - Praxis (Bern 1994). 2013 Jan 16;102(2):115. doi: 10.1024/1661-8157/a001175. PMID: - 23384956 -MH - Adrenergic beta-Antagonists/adverse effects/*therapeutic use -MH - Adult -MH - Aged -MH - Angiotensin Receptor Antagonists/therapeutic use -MH - Antihypertensive Agents/adverse effects/*therapeutic use -MH - Calcium Channel Blockers/therapeutic use -MH - Diuretics/therapeutic use -MH - Humans -MH - Hypertension/*drug therapy/mortality -MH - Middle Aged -MH - Randomized Controlled Trials as Topic -MH - Stroke/prevention & control -EDAT- 2012/08/17 06:00 -MHDA- 2012/09/27 06:00 -CRDT- 2012/08/17 06:00 -PHST- 2012/08/17 06:00 [entrez] -PHST- 2012/08/17 06:00 [pubmed] -PHST- 2012/09/27 06:00 [medline] -AID - 10.1002/14651858.CD002003.pub3 [doi] -PST - epublish -SO - Cochrane Database Syst Rev. 2012 Aug 15;(8):CD002003. doi: - 10.1002/14651858.CD002003.pub3. - -PMID- 19166097 -OWN - NLM -STAT- MEDLINE -DCOM- 20090209 -LR - 20171116 -IS - 0302-6469 (Print) -IS - 0302-6469 (Linking) -VI - 70 -IP - 4 -DP - 2008 -TI - [The effect of type II diabetes and the metabolic syndrome on cardiac second - window preconditioning]. -PG - 221-44 -AB - Preconditioning is the most powerful endogenous mechanism, to protect the heart - against ischemic damage. Conflicting data are published whether preconditioning - can be induced in case of diabetes and the metabolic syndrome, which are - clinically very relevant conditions. If preconditioning could be induced - consistently and chronically in this population, an important reduction of - surgical morbidity and mortality could be reached. In this project we induced - hypoxic preconditioning in mice and used cardiac pressure-conductance - catheterisation and infarct size as outcome parameters. In the first part, we - found that hypoxic preconditioning was capable to reduce infarct size with 40% - and preserve the load-independent parameters with 33% after coronary occlusion. A - DKO (double knock-out: ob/ob; LDLR-/-) model for the metabolic syndrome developed - a larger infarct size and had a reduced contractility. No preconditioning could - be induced in this model. To detect the determing factor of the resistance to - preconditioning, we used single knock-out models. A comparable preconditioning - effect of wild type mice could be induced in the lipoprotein receptor deficient - (LDLR-/-) model for dyslipidemia. The leptin deficient (ob/ob) model, - characterized by insulin resistance and abdominal obesity had, identically to the - DKO model, a larger infarct size. A second window of preconditioning could be - induced, although it was less pronounced than the wild type and LDLR-/- model. - Insulin resistance and abdominal obesity could be identified as the major factor - in the resistance to preconditioning. -FAU - Van Der Mieren, G -AU - Van Der Mieren G -AD - Afdeling Experimentele Cardiale Heelkunde, Departement Hart- en Vaatziekten, - KULeuven Minderbroedersstraat 19, Provisorium I, B 3000 Leuven. -FAU - Flameng, W -AU - Flameng W -FAU - Herijgers, P -AU - Herijgers P -LA - dut -PT - Journal Article -PT - Review -TT - Het effect van type ii diabetes en het metabool syndroom op cardiale tweede - venster preconditionering. -PL - Belgium -TA - Verh K Acad Geneeskd Belg -JT - Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie -JID - 0413210 -RN - 0 (Receptors, Lipoprotein) -SB - IM -MH - Animals -MH - Diabetes Mellitus, Type 2/*physiopathology -MH - Disease Models, Animal -MH - Dyslipidemias/*physiopathology -MH - Humans -MH - *Ischemic Preconditioning, Myocardial -MH - Metabolic Syndrome/*physiopathology -MH - Mice -MH - Mice, Knockout -MH - Receptors, Lipoprotein/*deficiency/genetics -RF - 37 -EDAT- 2009/01/27 09:00 -MHDA- 2009/02/10 09:00 -CRDT- 2009/01/27 09:00 -PHST- 2009/01/27 09:00 [entrez] -PHST- 2009/01/27 09:00 [pubmed] -PHST- 2009/02/10 09:00 [medline] -PST - ppublish -SO - Verh K Acad Geneeskd Belg. 2008;70(4):221-44. - -PMID- 16633990 -OWN - NLM -STAT- MEDLINE -DCOM- 20060728 -LR - 20061115 -IS - 0393-5590 (Print) -IS - 0393-5590 (Linking) -VI - 23 Suppl 34 -DP - 2006 Jan-Feb -TI - [Can cardiovascular calcifications be prevented in chronic kidney disease?]. -PG - S21-5 -AB - Chronic kidney disease, with special regard to hemodialysis patients, develop - frequent and widespread cardiac and vascular calcifications. In the heart - calcifications are mainly located in the coronary arteries and in the valvular - structures. There is a strict relation between cardiovascular mortality in CKD - and the extent of cardiac and vascular calcifications. Therefore it is important - to evaluate the causes of extraskeletal calcifications for the evaluation of the - possibility of prevention. The importance of hyperphosphatemia, of hypercalcemia - and of the increased CAxP product as a cause of cardiac calcification has been - clearly underlined. However the mechanism of calcification, initially considered - a physico-chemical precipitation, has been investigated with the conclusion that - the process is mediated by cellular differentiation and production of factors - favoring mineralization in the extracellular milieu. Increased serum phosphate - levels are able to induce a transformation of vascular smooth muscle cells into - osteoblast-like cells, able to produce factors known to be pro-mineralizing - agents in the bone tissue. Further studies have revealed the importance of a - number of inhibitors of calcification of cardiovascular structures, like - Fetuin-A, MGP, Osteopontin, Osteoprotegerin. Therefore at present the - calcification process of vascular tissue is considered to be linked to a balance - between inducers and inhibitors of calcium-phosphate deposits. Prevention of - cardiac calcifications is at present mainly based of optimal control of serum - phosphate and reduction of calcium load through the use of non-calcium containing - phosphate binders. Treatment with statins for prevention and treatment of - atherosclerosis is also an important means of decreasing the size and number of - atherosclerotic plaques, where a portion of the calcification process develops. -FAU - Coen, G -AU - Coen G -AD - Nefrologia ed Ipertensione, Ospedale Israelitico, Rome. - giorgio.coen@fastwebnet.it -FAU - Manni, M -AU - Manni M -FAU - Mantella, D -AU - Mantella D -FAU - Splendiani, G -AU - Splendiani G -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - E possibile prevenire i processi di calcificazione cardiovascolare nel paziente - con insufficienza renale cronica? -PL - Italy -TA - G Ital Nefrol -JT - Giornale italiano di nefrologia : organo ufficiale della Societa italiana di - nefrologia -JID - 9426434 -SB - IM -MH - Calcinosis/*etiology/*prevention & control -MH - Cardiovascular Diseases/*etiology/*prevention & control -MH - Humans -MH - Kidney Failure, Chronic/*complications -RF - 25 -EDAT- 2006/04/25 09:00 -MHDA- 2006/07/29 09:00 -CRDT- 2006/04/25 09:00 -PHST- 2006/04/25 09:00 [pubmed] -PHST- 2006/07/29 09:00 [medline] -PHST- 2006/04/25 09:00 [entrez] -PST - ppublish -SO - G Ital Nefrol. 2006 Jan-Feb;23 Suppl 34:S21-5. - -PMID- 16387626 -OWN - NLM -STAT- MEDLINE -DCOM- 20060518 -LR - 20061115 -IS - 1050-1738 (Print) -IS - 1050-1738 (Linking) -VI - 16 -IP - 1 -DP - 2006 Jan -TI - beta(1)-Adrenergic receptor function, autoimmunity, and pathogenesis of dilated - cardiomyopathy. -PG - 20-4 -AB - Dilated cardiomyopathy (DCM) is a heart disease characterized by progressive - depression of cardiac function and left ventricular dilatation of unknown - etiology in the absence of coronary artery disease. Genetic causes and - cardiotoxic substances account for about one third of the DCM cases, but the - etiology of the remaining 60% to 70% is still unclear. Over the past two decades, - evidence has accumulated continuously that functionally active antibodies or - autoantibodies targeting cardiac beta(1)-adrenergic receptors (anti-beta(1)-AR - antibodies) may play an important role in the initiation and/or clinical course - of DCM. Recent experiments in rats indicate that such antibodies can actually - cause DCM. This article reviews current knowledge and recent experimental and - clinical findings focusing on the role of the beta(1)-adrenergic receptor as a - self-antigen in the pathogenesis of DCM. -FAU - Jahns, Roland -AU - Jahns R -AD - Department of Internal Medicine, Medizinische Klinik und Poliklinik I, University - of Würzburg, D-97080 Würzburg, Germany. jahns_r@klinik.uni-wuerzburg.de -FAU - Boivin, Valérie -AU - Boivin V -FAU - Lohse, Martin J -AU - Lohse MJ -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Trends Cardiovasc Med -JT - Trends in cardiovascular medicine -JID - 9108337 -RN - 0 (Autoantibodies) -RN - 0 (Receptors, Adrenergic, beta-1) -SB - IM -MH - Animals -MH - Autoantibodies/*biosynthesis/blood/physiology -MH - *Autoimmunity -MH - Cardiomyopathy, Dilated/*etiology/immunology/physiopathology -MH - Humans -MH - Receptors, Adrenergic, beta-1/*immunology/physiology -RF - 50 -EDAT- 2006/01/03 09:00 -MHDA- 2006/05/19 09:00 -CRDT- 2006/01/03 09:00 -PHST- 2005/10/03 00:00 [received] -PHST- 2005/10/30 00:00 [revised] -PHST- 2005/11/07 00:00 [accepted] -PHST- 2006/01/03 09:00 [pubmed] -PHST- 2006/05/19 09:00 [medline] -PHST- 2006/01/03 09:00 [entrez] -AID - S1050-1738(05)00216-1 [pii] -AID - 10.1016/j.tcm.2005.11.002 [doi] -PST - ppublish -SO - Trends Cardiovasc Med. 2006 Jan;16(1):20-4. doi: 10.1016/j.tcm.2005.11.002. - -PMID- 21556974 -OWN - NLM -STAT- MEDLINE -DCOM- 20111114 -LR - 20211020 -IS - 1534-3170 (Electronic) -IS - 1523-3782 (Linking) -VI - 13 -IP - 4 -DP - 2011 Aug -TI - Optimal medical therapy, lifestyle intervention, and secondary prevention - strategies for cardiovascular event reduction in ischemic heart disease. -PG - 287-95 -LID - 10.1007/s11886-011-0190-5 [doi] -AB - Medical and lifestyle secondary prevention strategies are essential components - for reducing cardiovascular risk, irrespective of whether revascularization is - performed. In patients with coronary artery disease (CAD), recent clinical trials - have further clarified the management of lipid optimization, - renin-angiotensin-aldosterone system inhibition, antiplatelet therapy, and - diabetes. Still, many questions remain with regard to optimal secondary - prevention strategies in patients with CAD. Despite the significant reductions in - cardiovascular morbidity and mortality with secondary prevention therapies - demonstrated in clinical trials, long-term adherence to these interventions - remains relatively low, with reasons being multifactorial. One promising method - to improve compliance is the use of trained nurses/case managers to routinely - follow medications, and provide both lifestyle and behavioral counseling. - Implementation of this strategy led to significant improvements in medication - compliance and risk factor optimization, although these results require - confirmation in a randomized clinical study. Given that poor compliance has been - associated with worsening cardiovascular outcomes, effective CAD management - should include strategies for improving patient adherence to therapies that have - proven benefits. -FAU - Joseph, Philip -AU - Joseph P -AD - Population Health Research Institute, Hamilton Health Sciences-McMaster - University, ON, Canada, L8L 2X2. philip.joseph@phri.ca -FAU - Teo, Koon -AU - Teo K -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Diabetes Mellitus -MH - *Health Behavior -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - *Life Style -MH - Myocardial Ischemia/*drug therapy/prevention & control/therapy -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Renin-Angiotensin System/drug effects -MH - Risk Assessment/*methods -MH - Risk Reduction Behavior -MH - Secondary Prevention/*methods -MH - Time Factors -EDAT- 2011/05/11 06:00 -MHDA- 2011/11/15 06:00 -CRDT- 2011/05/11 06:00 -PHST- 2011/05/11 06:00 [entrez] -PHST- 2011/05/11 06:00 [pubmed] -PHST- 2011/11/15 06:00 [medline] -AID - 10.1007/s11886-011-0190-5 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2011 Aug;13(4):287-95. doi: 10.1007/s11886-011-0190-5. - -PMID- 18087640 -OWN - NLM -STAT- MEDLINE -DCOM- 20080418 -LR - 20121115 -IS - 1008-682X (Print) -IS - 1008-682X (Linking) -VI - 10 -IP - 1 -DP - 2008 Jan -TI - Growth factors for therapeutic angiogenesis in hypercholesterolemic erectile - dysfunction. -PG - 23-7 -AB - The past decade has seen an explosion of new information on the physiology of - penile erection, and pathophysiology of erectile dysfunction (ED). - Hypercholesterolemia is a chronic condition that can lead to degeneration in the - vasculature bed and can result in ED if the penile vasculature is involved. - Angiogenesis is the growth of new blood vessels from preexisting vasculature. - Therapeutic angiogenesis seeks to harness the mechanisms of vascular growth to - treat disorders of inadequate tissue perfusion, such as coronary artery disease - and ED. There have been tremendous changes in the field of therapeutic - angiogenesis over the past decade, and there is much promise for the future. - Initial preclinical work with cytokine growth factor delivery resulted in a great - deal of enthusiasm for the treatment of ischemic heart and/or peripheral vascular - disease, though clinical studies have not achieved similar success. With an - increased understanding of the complex mechanisms involved in angiogenesis, novel - therapies which target multiple different angiogenic pathways are also being - developed and tested. The penis is a convenient tissue target for gene therapy - because of its external location and accessibility, the ubiquity of endothelial - lined spaces, and low level of blood flow, especially in the flaccid state. - Therapeutic angiogenesis is an exciting field that continues to evolve. This - review will focus on the development of growth factors for hypercholesterolemic - ED, the use of various growth factors for ED therapy, their routes of delivery, - and the results in animal studies. -FAU - Xie, Donghua -AU - Xie D -AD - Duke University Medical Center Dur-ham, NC 27710, USA. -FAU - Annex, Brian H -AU - Annex BH -FAU - Donatucci, Craig F -AU - Donatucci CF -LA - eng -PT - Journal Article -PT - Review -PL - China -TA - Asian J Androl -JT - Asian journal of andrology -JID - 100942132 -RN - 0 (Vascular Endothelial Growth Factors) -RN - 103107-01-3 (Fibroblast Growth Factor 2) -RN - EC 1.14.13.39 (Nitric Oxide Synthase) -SB - IM -MH - Animals -MH - Erectile Dysfunction/*etiology/*therapy -MH - Fibroblast Growth Factor 2/genetics -MH - Gene Expression -MH - *Genetic Therapy -MH - Humans -MH - Hypercholesterolemia/*complications -MH - Male -MH - *Neovascularization, Physiologic -MH - Nitric Oxide Synthase/genetics -MH - Vascular Endothelial Growth Factors/genetics -RF - 57 -EDAT- 2007/12/19 09:00 -MHDA- 2008/04/19 09:00 -CRDT- 2007/12/19 09:00 -PHST- 2007/12/19 09:00 [pubmed] -PHST- 2008/04/19 09:00 [medline] -PHST- 2007/12/19 09:00 [entrez] -AID - 10.1111/j.1745-7262.2008.00372.x [doi] -PST - ppublish -SO - Asian J Androl. 2008 Jan;10(1):23-7. doi: 10.1111/j.1745-7262.2008.00372.x. - -PMID- 23863802 -OWN - NLM -STAT- MEDLINE -DCOM- 20150113 -LR - 20211021 -IS - 1476-5527 (Electronic) -IS - 0950-9240 (Linking) -VI - 28 -IP - 3 -DP - 2014 Mar -TI - CYP3A5 polymorphism, amlodipine and hypertension. -PG - 145-9 -LID - 10.1038/jhh.2013.67 [doi] -AB - As a major cardiovascular risk factor for stroke, coronary artery disease, heart - failure and end-stage renal disease, hypertension affects approximately one - billion people and causes large economic burden worldwide. Cytochrome P450 3A5 - (CYP3A5), belonging to the CYP3A subfamily, has been implicated in the regulation - of blood pressure and may serve as a potential risk factor for the development of - hypertension. Increased CYP3A5 activity could cause sodium and water retention by - affecting the metabolism of cortisol in the kidneys. Furthermore, polymorphic - CYP3A5 genotypes have been shown to cause differences in blood pressure response - to antihypertensive drugs. Several studies have investigated the role of CYP3A5 - in blood pressure response to amlodipine. However, recent data on the role of - CYP3A5 in hypertension development and treatment are inconsistent. This review - summarizes what is known regarding the relationship of CYP3A5 with hypertension, - discusses the limitations in present studies, highlights the gaps and directs - research to this field. -FAU - Zhang, Y-P -AU - Zhang YP -AD - 1] Department of Cardiology, the Third Xiang-Ya Hospital, Central South - University, Changsha, People's Republic of China [2] Center of Clinical - Pharmacology, the Third Xiang-Ya Hospital, Central South University, Changsha, - China. -FAU - Zuo, X-C -AU - Zuo XC -AD - Center of Clinical Pharmacology, the Third Xiang-Ya Hospital, Central South - University, Changsha, China. -FAU - Huang, Z-J -AU - Huang ZJ -AD - Center of Clinical Pharmacology, the Third Xiang-Ya Hospital, Central South - University, Changsha, China. -FAU - Cai, J-J -AU - Cai JJ -AD - 1] Department of Cardiology, the Third Xiang-Ya Hospital, Central South - University, Changsha, People's Republic of China [2] Center of Clinical - Pharmacology, the Third Xiang-Ya Hospital, Central South University, Changsha, - China. -FAU - Wen, J -AU - Wen J -AD - 1] Department of Cardiology, the Third Xiang-Ya Hospital, Central South - University, Changsha, People's Republic of China [2] Center of Clinical - Pharmacology, the Third Xiang-Ya Hospital, Central South University, Changsha, - China. -FAU - Duan, D D -AU - Duan DD -AD - Laboratory of Cardiovascular Phenomics, the Department of Pharmacology, - University of Nevada School of Medicine, Reno, NV, USA. -FAU - Yuan, H -AU - Yuan H -AD - 1] Department of Cardiology, the Third Xiang-Ya Hospital, Central South - University, Changsha, People's Republic of China [2] Center of Clinical - Pharmacology, the Third Xiang-Ya Hospital, Central South University, Changsha, - China. -LA - eng -GR - R01 HL113598/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130718 -PL - England -TA - J Hum Hypertens -JT - Journal of human hypertension -JID - 8811625 -RN - 0 (Antihypertensive Agents) -RN - 1J444QC288 (Amlodipine) -RN - EC 1.14.14.1 (CYP3A5 protein, human) -RN - EC 1.14.14.1 (Cytochrome P-450 CYP3A) -SB - IM -MH - Amlodipine/*pharmacology -MH - Antihypertensive Agents/*pharmacology -MH - Cytochrome P-450 CYP3A/*genetics -MH - Genotype -MH - Humans -MH - Hypertension/*drug therapy/*genetics -MH - *Polymorphism, Genetic -EDAT- 2013/07/19 06:00 -MHDA- 2015/01/15 06:00 -CRDT- 2013/07/19 06:00 -PHST- 2013/03/10 00:00 [received] -PHST- 2013/06/12 00:00 [revised] -PHST- 2013/06/13 00:00 [accepted] -PHST- 2013/07/19 06:00 [entrez] -PHST- 2013/07/19 06:00 [pubmed] -PHST- 2015/01/15 06:00 [medline] -AID - jhh201367 [pii] -AID - 10.1038/jhh.2013.67 [doi] -PST - ppublish -SO - J Hum Hypertens. 2014 Mar;28(3):145-9. doi: 10.1038/jhh.2013.67. Epub 2013 Jul - 18. - -PMID- 19605962 -OWN - NLM -STAT- MEDLINE -DCOM- 20091008 -LR - 20180614 -IS - 1648-9144 (Electronic) -IS - 1010-660X (Linking) -VI - 45 -IP - 6 -DP - 2009 -TI - Markers of endothelial dysfunction after cardiac surgery: soluble forms of - vascular-1 and intercellular-1 adhesion molecules. -PG - 434-9 -AB - Endothelium forms an inner layer of vascular wall. It plays an important role in - inflammatory process, regulation of vascular tone, and synthesis of - thromboregulatory substances. Leukocyte and endothelium interactions during - inflammation are regulated by different families of adhesion molecules. Increased - levels of soluble forms of adhesion molecules have been detected in the - circulating blood in conditions such as autoimmune diseases, transplant - rejection, ischemia-reperfusion injury in addition to neutrophil- and endothelial - membrane-bound forms reflecting the level of endothelial dysfunction. It is known - that endothelial dysfunction is a risk factor for ischemic events such as stroke, - myocardial infarction, unstable angina pectoris, ventricle fibrillation, - necessity of revascularisation procedures, and death from cardiovascular reasons. - Clinical studies showed that cardiac surgery has an impact on vascular - endothelial function as well. The amount of endothelium-derived soluble forms of - vascular-1 and intercellular-1 adhesion molecules increases after cardiopulmonary - bypass suggesting endothelial dysfunction. However, further investigations are - needed to be done to support the evidence that endothelial dysfunction proceeding - heart surgery is one of the reasons of tissue ischemia-reperfusion injury. -FAU - Balciūnas, Mindaugas -AU - Balciūnas M -AD - Department of Pathology, Forensic Medicine and Pharmacology, Faculty of Medicine, - Vilnius University, Lithuania. mindaugas.balciunas@santa.lt -FAU - Bagdonaite, Loreta -AU - Bagdonaite L -FAU - Samalavicius, Robertas -AU - Samalavicius R -FAU - Baublys, Alis -AU - Baublys A -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - Switzerland -TA - Medicina (Kaunas) -JT - Medicina (Kaunas, Lithuania) -JID - 9425208 -RN - 0 (Biomarkers) -RN - 0 (Vascular Cell Adhesion Molecule-1) -RN - 126547-89-5 (Intercellular Adhesion Molecule-1) -SB - IM -MH - Adult -MH - Animals -MH - Biomarkers -MH - Cardiac Output, Low/etiology -MH - *Cardiac Surgical Procedures -MH - Cardiopulmonary Bypass -MH - Child -MH - Clinical Trials as Topic -MH - Coronary Artery Bypass -MH - Disease Models, Animal -MH - Endothelium, Vascular/*physiopathology -MH - Female -MH - Humans -MH - Infant -MH - Intensive Care Units -MH - *Intercellular Adhesion Molecule-1/blood -MH - Male -MH - Prospective Studies -MH - Reperfusion Injury/prevention & control -MH - Risk Factors -MH - Sheep -MH - Time Factors -MH - *Vascular Cell Adhesion Molecule-1/blood -RF - 58 -EDAT- 2009/07/17 09:00 -MHDA- 2009/10/09 06:00 -CRDT- 2009/07/17 09:00 -PHST- 2009/07/17 09:00 [entrez] -PHST- 2009/07/17 09:00 [pubmed] -PHST- 2009/10/09 06:00 [medline] -AID - 0906-02 [pii] -PST - ppublish -SO - Medicina (Kaunas). 2009;45(6):434-9. - -PMID- 23731734 -OWN - NLM -STAT- MEDLINE -DCOM- 20140515 -LR - 20161125 -IS - 2174-2030 (Electronic) -IS - 0870-2551 (Linking) -VI - 32 -IP - 6 -DP - 2013 Jun -TI - Iodine-123-metaiodobenzylguanidine scintigraphy in risk stratification of sudden - death in heart failure. -PG - 509-16 -LID - S0870-2551(13)00034-6 [pii] -LID - 10.1016/j.repc.2012.11.003 [doi] -AB - Metaiodobenzylguanidine (MIBG) is a false neurotransmitter noradrenaline analogue - that is taken up by the 'uptake 1' transporter mechanism in the cell membrane of - presynaptic adrenergic neurons and accumulates in catecholamine storage vesicles. - Since it is practically unmetabolized, it can be labeled with a radioisotope - (iodine-123) in scintigraphic exams to noninvasively assess the functional status - of the sympathetic innervation of organs with a significant adrenergic component, - including the heart. Studies of its application in nuclear cardiology appear to - confirm its value in the assessment of conditions such as coronary artery - disease, heart failure, arrhythmias and sudden death. Heart failure is a global - problem, with an estimated prevalence of 2% in developed countries. Sudden - cardiac death is the main cause of its high mortality. The autonomic nervous - system dysfunction, including sympathetic hyperactivity, that accompanies chronic - heart failure is associated with progressive myocardial remodeling, declining - left ventricular function and worsening symptoms, and contributes to the - development of ventricular arrhythmias and sudden death. Since 123I-MIBG cardiac - scintigraphy can detect changes in the cardiac adrenergic system, there is - considerable interest in its role in obtaining diagnostic and prognostic - information in patients with heart failure. In this article we present a - literature review on the use of 123I-MIBG scintigraphy for risk stratification of - sudden death in patients with heart failure. -CI - Copyright © 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier - España. All rights reserved. -FAU - Martins da Silva, Marta Inês -AU - Martins da Silva MI -AD - Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal. - martainesilva@gmail.com -FAU - Vidigal Ferreira, Maria João -AU - Vidigal Ferreira MJ -FAU - Morão Moreira, Ana Paula -AU - Morão Moreira AP -LA - eng -LA - por -PT - Journal Article -PT - Review -DEP - 20130602 -PL - Portugal -TA - Rev Port Cardiol -JT - Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de - Cardiologia = Portuguese journal of cardiology : an official journal of the - Portuguese Society of Cardiology -JID - 8710716 -RN - 0 (Radiopharmaceuticals) -RN - 35MRW7B4AD (3-Iodobenzylguanidine) -SB - IM -MH - *3-Iodobenzylguanidine -MH - *Death, Sudden, Cardiac -MH - Defibrillators, Implantable -MH - Heart Failure/*diagnostic imaging/physiopathology/surgery -MH - Humans -MH - Preoperative Care -MH - Prognosis -MH - Radionuclide Imaging -MH - *Radiopharmaceuticals -MH - Risk Assessment/methods -MH - Sympathetic Nervous System/physiopathology -OTO - NOTNLM -OT - Arritmias cardíacas -OT - Cardiac arrhythmias -OT - Cintigrafia com iodo-123-metaiodobenzilguanidina -OT - Heart failure -OT - Insuficiência cardíaca -OT - Iodine-123-metaiodobenzylguanidine scintigraphy -OT - Morte súbita cardíaca -OT - Sistema nervoso simpático -OT - Sudden cardiac death -OT - Sympathetic nervous system -EDAT- 2013/06/05 06:00 -MHDA- 2014/05/16 06:00 -CRDT- 2013/06/05 06:00 -PHST- 2012/09/24 00:00 [received] -PHST- 2012/11/01 00:00 [accepted] -PHST- 2013/06/05 06:00 [entrez] -PHST- 2013/06/05 06:00 [pubmed] -PHST- 2014/05/16 06:00 [medline] -AID - S0870-2551(13)00034-6 [pii] -AID - 10.1016/j.repc.2012.11.003 [doi] -PST - ppublish -SO - Rev Port Cardiol. 2013 Jun;32(6):509-16. doi: 10.1016/j.repc.2012.11.003. Epub - 2013 Jun 2. - -PMID- 16770977 -OWN - NLM -STAT- MEDLINE -DCOM- 20060712 -LR - 20131213 -IS - 0025-6196 (Print) -IS - 0025-6196 (Linking) -VI - 81 -IP - 6 -DP - 2006 Jun -TI - Surgical treatment of the cardiac manifestations of relapsing polychondritis: - overview of 33 patients identified through literature review and the Mayo Clinic - records. -PG - 772-6 -AB - OBJECTIVES: To analyze the cardiac findings that necessitate surgery in patients - with relapsing polychondritis (RP) and to compare our results to cases in the - literature. MATERIAL AND METHODS: A systematic overview of the literature was - completed with the addition of cases of RP from the Mayo patient population that - necessitated cardiac surgery. RESULTS: Thirty-three patients were identified (25 - from the literature and 8 from the Mayo patient population). Nine patients (27%) - were female, 22 (67%) were male, and sex was not stated for 2 patients (6%). The - patient age ranged from 17 to 69 years (mean +/- SD, 42.5 +/- 15.7 years). At - operation, 30 patients (91%) had aortic regurgitation, 21 (64%) had aortic root - disease, and 13 (39%) had mitral regurgitation. The most common surgical - procedure performed was aortic valve replacement in 12 patients (36%). The most - common complications were death in 12 patients (36%) and prosthetic valve - dehiscence in 4 patients (12%). CONCLUSIONS: Cardiac involvement is more - prominent in the male population and requires more invasive procedures. Aortic - valve replacement with composite graft replacement of the ascending aorta along - with coronary artery ostial reimplantation should be considered in these - patients. Postsurgical valvular complications include prosthetic dehiscence, - paravalvular leakage, mediastinitis, and heart failure, and these complications - are associated with postoperative corticosteroid therapy. Initiation of - second-line immunosuppressive therapy should be substituted for corticosteroids - after cardiac surgery. -FAU - Dib, Chadi -AU - Dib C -AD - Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, - Minn 55905, USA. -FAU - Moustafa, Sherif E -AU - Moustafa SE -FAU - Mookadam, Martina -AU - Mookadam M -FAU - Zehr, Kenton J -AU - Zehr KJ -FAU - Michet, Clement J Jr -AU - Michet CJ Jr -FAU - Mookadam, Farouk -AU - Mookadam F -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - England -TA - Mayo Clin Proc -JT - Mayo Clinic proceedings -JID - 0405543 -RN - 0 (Immunosuppressive Agents) -SB - IM -MH - Adolescent -MH - Adult -MH - Aged -MH - *Cardiac Surgical Procedures/adverse effects -MH - Female -MH - Heart Diseases/diagnosis/*etiology/*surgery -MH - Heart Valve Diseases/diagnosis/etiology/surgery -MH - Heart Valve Prosthesis Implantation -MH - Humans -MH - Immunosuppressive Agents/therapeutic use -MH - Male -MH - Middle Aged -MH - Polychondritis, Relapsing/*complications -MH - Postoperative Care -MH - Retrospective Studies -RF - 37 -EDAT- 2006/06/15 09:00 -MHDA- 2006/07/13 09:00 -CRDT- 2006/06/15 09:00 -PHST- 2006/06/15 09:00 [pubmed] -PHST- 2006/07/13 09:00 [medline] -PHST- 2006/06/15 09:00 [entrez] -AID - S0025-6196(11)61731-X [pii] -AID - 10.4065/81.6.772 [doi] -PST - ppublish -SO - Mayo Clin Proc. 2006 Jun;81(6):772-6. doi: 10.4065/81.6.772. - -PMID- 21453027 -OWN - NLM -STAT- MEDLINE -DCOM- 20110809 -LR - 20110401 -IS - 1744-8298 (Electronic) -IS - 1479-6678 (Linking) -VI - 7 -IP - 2 -DP - 2011 Mar -TI - Delayed and indirect effects of antiarrhythmic drugs in reducing sudden cardiac - death. -PG - 203-17 -LID - 10.2217/fca.11.3 [doi] -AB - In the USA, two-thirds of sudden cardiac deaths (SCDs) are caused by sustained - ventricular tachycardia and ventricular fibrillation. Implantable cardioverter - defibrillator (ICD) therapy has been demonstrated to decrease mortality caused by - these arrhythmias, when used both for primary and secondary prevention. However, - ICD use is expensive, has proarrhythmic effects and does not prevent ventricular - arrhythmias. Antiarrhythmic drugs (AADs) can be used for acute or chronic therapy - to prevent ventricular arrhythmias and SCD. Most commonly, AADs are often used in - patients with an ICD who have recurrent ICD shocks due to ventricular - arrhythmias. Class I AADs are used in patients with a structurally normal heart - and are contraindicated in patients with structural heart disease. β-blockers - have been demonstrated to be beneficial in preventing mortality and malignant - tachyarrhythmias in postmyocardial infarction and congestive heart failure - patients, and in patients who have an ICD. Amiodarone has a neutral effect on - mortality, while other class III drugs may increase mortality in certain - subgroups of patients. Dronedarone, a new class III drug, may reduce mortality, - but sufficient data are not available to allow for its use in the prevention of - malignant tachyarrhythmias. Few drugs that are not classified as AADs can also - prevent arrhythmias, via their beneficial effects on cardiovascular remodeling. - These non-ADDs have delayed and indirect effects, which are mediated by the - renin-angiotensin-aldosterone system and lipid metabolism - n-3 polyunsaturated - fatty acids (fish oil), and statins, and can thus can reduce the likelihood of - future malignant ventricular arrhythmias in patients with coronary artery disease - or congestive heart failure. The role of chronic drug therapy alone for primary - and secondary prevention of SCD is less than desirable because of proarrhythmic - and adverse side effects. The non-ADDs are well tolerated and have no - proarrhythmic actions, thus their benefit could outweigh risks, although - currently there are no concrete data to suggest this. -FAU - Malhotra, Saurabh -AU - Malhotra S -AD - Krannert Institute of Cardiology, Indiana University School of Medicine, - Indianapolis, IN, USA. -FAU - Das, Mithilesh K -AU - Das MK -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Future Cardiol -JT - Future cardiology -JID - 101239345 -RN - 0 (Anti-Arrhythmia Agents) -SB - IM -MH - Anti-Arrhythmia Agents/*therapeutic use -MH - *Arrhythmias, Cardiac/complications/drug therapy/mortality -MH - *Death, Sudden, Cardiac/epidemiology/etiology/prevention & control -MH - Humans -MH - Incidence -MH - Survival Rate/trends -MH - United States/epidemiology -EDAT- 2011/04/02 06:00 -MHDA- 2011/08/10 06:00 -CRDT- 2011/04/02 06:00 -PHST- 2011/04/02 06:00 [entrez] -PHST- 2011/04/02 06:00 [pubmed] -PHST- 2011/08/10 06:00 [medline] -AID - 10.2217/fca.11.3 [doi] -PST - ppublish -SO - Future Cardiol. 2011 Mar;7(2):203-17. doi: 10.2217/fca.11.3. - -PMID- 20465366 -OWN - NLM -STAT- MEDLINE -DCOM- 20100928 -LR - 20191210 -IS - 1473-4877 (Electronic) -IS - 0300-7995 (Linking) -VI - 26 -IP - 7 -DP - 2010 Jul -TI - Are we failing to document adequate smoking histories? A brief review 1999-2009. -PG - 1691-6 -LID - 10.1185/03007995.2010.486574 [doi] -AB - BACKGROUND: Documenting a detailed smoking history is of obvious importance. - Failure to adequately document the smoking history may result in the misdiagnosis - and management of asthma, and may be associated with a deficiency of care in - patients with cardiovascular disease and several other common diseases. SCOPE: - The purpose of this article is to review the evidence over the past decade that - demonstrates inadequate documentation of smoking history. A literature search of - English language journals from 1999 to 2009 was completed using several - databases, including PubMed, MEDLINE, EMBASE, and SCOPUS. FINDINGS: Fourteen - studies demonstrated inadequate documentation of smoking histories by primary - care clinicians, specialists, residents, and medical students. Failure to - document smoking histories was observed in patients with conditions such as heart - failure, coronary artery disease, and asthma. Electronic decision support systems - and simple medical record reminders were effective in improving the documentation - of smoking histories. CONCLUSIONS: Failure to adequately document the smoking - history appears to be common. Strategies such as electronic decision support - systems are needed to correct this problem in order for patients to receive - optimal therapy for their appropriate diagnoses. -FAU - Self, Timothy H -AU - Self TH -AD - University of Tennessee Health Science Center; Methodist University Hospital, - Memphis, TN 38163, USA. tself@uthsc.edu -FAU - Wallace, Jessica L -AU - Wallace JL -FAU - Gray, Lori Arnold -AU - Gray LA -FAU - Usery, Justin B -AU - Usery JB -FAU - Finch, Christopher K -AU - Finch CK -FAU - Deaton, Paul R -AU - Deaton PR -LA - eng -PT - Evaluation Study -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Curr Med Res Opin -JT - Current medical research and opinion -JID - 0351014 -RN - 0 (Tobacco Smoke Pollution) -SB - IM -MH - Asthma/epidemiology/etiology -MH - Cardiovascular Diseases/epidemiology/etiology -MH - Documentation/standards -MH - Humans -MH - Medical History Taking/*standards -MH - Medical Records -MH - *Smoking/adverse effects/epidemiology -MH - Tobacco Smoke Pollution/adverse effects -MH - United States/epidemiology -RF - 27 -EDAT- 2010/05/15 06:00 -MHDA- 2010/09/30 06:00 -CRDT- 2010/05/15 06:00 -PHST- 2010/05/15 06:00 [entrez] -PHST- 2010/05/15 06:00 [pubmed] -PHST- 2010/09/30 06:00 [medline] -AID - 10.1185/03007995.2010.486574 [doi] -PST - ppublish -SO - Curr Med Res Opin. 2010 Jul;26(7):1691-6. doi: 10.1185/03007995.2010.486574. - -PMID- 18480528 -OWN - NLM -STAT- MEDLINE -DCOM- 20090505 -LR - 20220311 -IS - 0972-2823 (Electronic) -IS - 0022-3859 (Linking) -VI - 54 -IP - 2 -DP - 2008 Apr-Jun -TI - Present status of understanding on the genetic etiology of polycystic ovary - syndrome. -PG - 115-25 -AB - Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of - reproductive age with a prevalence of approximately 7-10% worldwide. PCOS - reflects multiple potential aetiologies and variable clinical manifestations. - This syndrome is characterized by serious health implications such as diabetes, - coronary heart diseases and cancer and also leads to infertility. PCOS can be - viewed as a heterogeneous androgen excess disorder with varying degrees of - reproductive and metabolic abnormalities determined by the interaction of - multiple genetic and environmental factors. In this paper, we have attempted a - comprehensive review of primarily molecular genetic studies done so far on PCOS. - We have also covered the studies focusing on the environmental factors and impact - of ethnicity on the presentation of this syndrome. A large number of studies have - been attempted to understand the aetiological mechanisms behind PCOS both at the - clinical and molecular genetic levels. In the Indian context, majority of the - PCOS studies have been confined to the clinical dimensions. However, a concrete - genetic mechanism behind the manifestation of PCOS is yet to be ascertained. - Understanding of this complex disorder requires comprehensive studies - incorporating relatively larger homogenous samples for genetic analysis and - taking into account the ethnicity and the environmental conditions of the - population/cohort under study. Research focused on these aspects may provide - better understanding on the genetic etiology and the interaction between genes - and environment, which may help develop new treatment methods and possible - prevention of the syndrome. -FAU - Dasgupta, S -AU - Dasgupta S -AD - Molecular Anthropology Group, Biological Anthropology Unit, Indian Statistical - Institute, Habsiguda, Hyderabad - 500 007, India. -FAU - Reddy, B Mohan -AU - Reddy BM -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - India -TA - J Postgrad Med -JT - Journal of postgraduate medicine -JID - 2985196R -SB - IM -MH - *Environment -MH - Epigenesis, Genetic -MH - Female -MH - Genetic Predisposition to Disease/*ethnology -MH - Humans -MH - India -MH - Polycystic Ovary Syndrome/ethnology/*genetics/physiopathology -MH - Prevalence -RF - 93 -EDAT- 2008/05/16 09:00 -MHDA- 2009/05/06 09:00 -CRDT- 2008/05/16 09:00 -PHST- 2008/05/16 09:00 [pubmed] -PHST- 2009/05/06 09:00 [medline] -PHST- 2008/05/16 09:00 [entrez] -AID - 10.4103/0022-3859.40778 [doi] -PST - ppublish -SO - J Postgrad Med. 2008 Apr-Jun;54(2):115-25. doi: 10.4103/0022-3859.40778. - -PMID- 19075607 -OWN - NLM -STAT- MEDLINE -DCOM- 20090310 -LR - 20220321 -IS - 1570-1638 (Print) -IS - 1570-1638 (Linking) -VI - 5 -IP - 4 -DP - 2008 Dec -TI - Ex vivo and in vivo approaches to study mechanisms of cardioprotection targeting - ischemia/reperfusion (i/r) injury: useful techniques for cardiovascular drug - discovery. -PG - 269-78 -AB - The last few decades have seen significant advancement in the therapy of Ischemic - Heart Diseases (IHD). This is a direct outcome of the increasing knowledge of the - molecular mechanisms involved during an ischemic insult of the myocardium. Even - then there is still a major unmet need for better strategies or drug therapies to - reduce ventricular remodeling and improve post-ischemic myocardial function. The - ex-vivo isolated working heart model and the in vivo myocardial infarction model - are the best known techniques to elucidate the contribution of a drug therapy to - confer cardioprotection in the event of an ischemic insult/reperfusion. Our - review aims to provide an insight into the state of the art techniques that lay - the foundations for cardiovascular drug discovery and present the prospects for - further development from a preclinical perspective. The first section of the - review provides an overview of the rat/mouse ex-vivo and in vivo models of - myocardial ischemia. The following section will then present various applications - of these clinically relevant models in characterizing cardiac functions, - screening for drugs and identifying the drug induced changes in cardiac - functions. Finally the role of these models in drug development is discussed with - respect to functional relevance of drug treatment on heart rate, aortic flow, - coronary flow, infarct size and the mechanisms by which these drugs promote - myocardial protection. This review may serve as a basic knowledge for researchers - who intend to study the efficacy of a drug in the treatment of ischemic heart - diseases. -FAU - Vidavalur, Ramesh -AU - Vidavalur R -AD - Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, - University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT - 06030-1110, USA. -FAU - Swarnakar, Snehasikta -AU - Swarnakar S -FAU - Thirunavukkarasu, Mahesh -AU - Thirunavukkarasu M -FAU - Samuel, Samson Mathews -AU - Samuel SM -FAU - Maulik, Nilanjana -AU - Maulik N -LA - eng -GR - HL-56803/HL/NHLBI NIH HHS/United States -GR - HL-69910/HL/NHLBI NIH HHS/United States -GR - HL-85804/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United Arab Emirates -TA - Curr Drug Discov Technol -JT - Current drug discovery technologies -JID - 101157212 -RN - 0 (Cardiotonic Agents) -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Animals -MH - Cardiotonic Agents/*pharmacology -MH - Cardiovascular Agents/therapeutic use -MH - *Disease Models, Animal -MH - Drug Discovery/*methods -MH - In Vitro Techniques -MH - Mice -MH - Myocardial Ischemia/drug therapy/physiopathology -MH - Perfusion -MH - Rats -MH - Reperfusion Injury/*drug therapy/physiopathology -MH - *Technology, Pharmaceutical -MH - Ventricular Remodeling/drug effects -RF - 97 -EDAT- 2008/12/17 09:00 -MHDA- 2009/03/11 09:00 -CRDT- 2008/12/17 09:00 -PHST- 2008/12/17 09:00 [entrez] -PHST- 2008/12/17 09:00 [pubmed] -PHST- 2009/03/11 09:00 [medline] -AID - 10.2174/157016308786733555 [doi] -PST - ppublish -SO - Curr Drug Discov Technol. 2008 Dec;5(4):269-78. doi: 10.2174/157016308786733555. - -PMID- 23448535 -OWN - NLM -STAT- MEDLINE -DCOM- 20150715 -LR - 20130404 -IS - 1440-1681 (Electronic) -IS - 0305-1870 (Linking) -VI - 40 -IP - 4 -DP - 2013 Apr -TI - Functional relevance of genetic variations of endothelial nitric oxide synthase - and vascular endothelial growth factor in diabetic coronary microvessel - dysfunction. -PG - 253-61 -LID - 10.1111/1440-1681.12070 [doi] -AB - The prevalence of type 1 diabetes (T1D) is increasing worldwide and is associated - with significant microvessel complications, of which nephropathy, retinopathy and - neuropathy are the most commonly studied. Although clinically evident - microvascular complications of diabetes are rarely seen in childhood, early - vascular abnormalities develop during childhood and accelerate during puberty. - Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis, - which is regulated by endothelial nitric oxide synthase (NOS3) at several levels. - Together, VEGF and NOS3 play an important role in the pathogenesis of the - microvascular complications of diabetes. Genetic variations in NOS3 and VEGF - critically regulate endothelial survival and function and increase the - susceptibility of patients to develop severe microvessel complications. - Identification of the risk factors for and improved understanding of the - subclinical signs of these diabetic microvascular complications will enable - implementation of therapeutic strategies, potentially changing the course of - vascular complications and improving the prognosis of children, adolescents and - young adults with diabetes. Moreover, early detection of these variations may - have a prognostic value or may suggest interventional approaches to regulate - these proteins in patients with diabetes. -CI - © 2013 The Authors Clinical and Experimental Pharmacology and Physiology © 2013 - Wiley Publishing Asia Pty Ltd. -FAU - Joshi, Mandar S -AU - Joshi MS -AD - Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia. - mandar.joshi@bakeridi.edu.au -FAU - Berger, Philip J -AU - Berger PJ -FAU - Kaye, David M -AU - Kaye DM -FAU - Pearson, James T -AU - Pearson JT -FAU - Bauer, John A -AU - Bauer JA -FAU - Ritchie, Rebecca H -AU - Ritchie RH -LA - eng -PT - Journal Article -PT - Review -PL - Australia -TA - Clin Exp Pharmacol Physiol -JT - Clinical and experimental pharmacology & physiology -JID - 0425076 -RN - 0 (VEGFA protein, human) -RN - 0 (Vascular Endothelial Growth Factor A) -RN - EC 1.14.13.39 (NOS3 protein, human) -RN - EC 1.14.13.39 (Nitric Oxide Synthase Type III) -SB - IM -MH - Adolescent -MH - Adult -MH - Child -MH - Coronary Vessels/*physiopathology -MH - Diabetes Mellitus, Type 1/*complications/*genetics/physiopathology -MH - Diabetic Angiopathies/*genetics/physiopathology -MH - Genetic Predisposition to Disease -MH - Humans -MH - Microvessels/physiopathology -MH - Nitric Oxide Synthase Type III/*genetics -MH - Polymorphism, Genetic -MH - Vascular Endothelial Growth Factor A/*genetics -MH - Young Adult -EDAT- 2013/03/02 06:00 -MHDA- 2015/07/16 06:00 -CRDT- 2013/03/02 06:00 -PHST- 2012/09/28 00:00 [received] -PHST- 2013/02/18 00:00 [revised] -PHST- 2013/02/19 00:00 [accepted] -PHST- 2013/03/02 06:00 [entrez] -PHST- 2013/03/02 06:00 [pubmed] -PHST- 2015/07/16 06:00 [medline] -AID - 10.1111/1440-1681.12070 [doi] -PST - ppublish -SO - Clin Exp Pharmacol Physiol. 2013 Apr;40(4):253-61. doi: 10.1111/1440-1681.12070. - -PMID- 16465387 -OWN - NLM -STAT- MEDLINE -DCOM- 20060321 -LR - 20081121 -IS - 1107-3756 (Print) -IS - 1107-3756 (Linking) -VI - 17 -IP - 3 -DP - 2006 Mar -TI - Interaction between heat shock protein 70 kDa and calcineurin in cardiovascular - systems (Review). -PG - 419-23 -AB - Cells have the capability of defending themselves from various stressors by - activating a genetic program with the production of substances known as heat - shock proteins (Hsps) and their regulatory partners, the heat shock transcription - factors. Hsps play a major role in systemic hypertension, coronary artery - disease, carotid atherosclerosis, myocardial infarction and myocardial ischemia. - In this review we discuss the interaction between Hsp70 and CaN which was carried - out in our laboratory. We demonstrated that the cardiac Hsp70 stimulated a 2-fold - increase in calcineurin (CaN) activity. In addition, the pull-down assay revealed - that Hsp70 directly interacts with CaN. Furthermore, expressed cardiac specific - Hsp70 was phosphorylated in vitro by cAMP-dependent protein kinase. The - phosphorylated Hsp70 was unable to activate the phosphatase activity of CaN. For - the first time we demonstrated that Hsp70 is phosphorylated by cAMP-dependent - protein kinase and provides an on/off switch for the regulation of CaN signaling - by Hsp70. This will lead to therapeutic benefit in human diseases such as - atherosclerosis, cardiomyopathy, congestive heart failure, and ischemia. -FAU - Lakshmikuttyamma, Ashakumary -AU - Lakshmikuttyamma A -AD - Department of Pathology, College of Medicine and Health Research Division, - Saskatchewan Cancer Agency, University of Saskatchewan, Saskatoon, Canada. -FAU - Selvakumar, Ponniah -AU - Selvakumar P -FAU - Sharma, Rajendra K -AU - Sharma RK -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Greece -TA - Int J Mol Med -JT - International journal of molecular medicine -JID - 9810955 -RN - 0 (HSP70 Heat-Shock Proteins) -RN - EC 3.1.3.16 (Calcineurin) -SB - IM -MH - Calcineurin/*metabolism -MH - Cardiovascular System/*metabolism -MH - HSP70 Heat-Shock Proteins/*metabolism -MH - Humans -MH - Phosphorylation -MH - Protein Binding -RF - 56 -EDAT- 2006/02/09 09:00 -MHDA- 2006/03/22 09:00 -CRDT- 2006/02/09 09:00 -PHST- 2006/02/09 09:00 [pubmed] -PHST- 2006/03/22 09:00 [medline] -PHST- 2006/02/09 09:00 [entrez] -PST - ppublish -SO - Int J Mol Med. 2006 Mar;17(3):419-23. - -PMID- 20715922 -OWN - NLM -STAT- MEDLINE -DCOM- 20101207 -LR - 20100818 -IS - 1744-8379 (Electronic) -IS - 1473-7167 (Linking) -VI - 10 -IP - 4 -DP - 2010 Aug -TI - Economic evaluations on cardiovascular preventive interventions in Argentina. -PG - 465-73 -LID - 10.1586/erp.10.50 [doi] -AB - Cardiovascular diseases are the main cause of death in Argentina. This article - analyzes economic evaluations on cardiovascular prevention for this country. A - literature search was conducted in five electronic databases during December - 2009. Inclusion criteria were complete economic evaluations addressing at least - one cardiovascular health outcome for the Argentinean population. Finally, nine - studies were included evaluating 14 comparisons. Interventions oriented to - primary or secondary prevention in patients that had undergone coronary - angioplasty, with a previous cardiovascular event or equivalents, with a - hospitalization for heart failure or general population were evaluated. Bread - salt reduction, antihypertensive treatment, mass educational campaigns and - polypill strategies could be considered cost effective. The available economic - evidence to guide resource allocation in cardiovascular disease in Argentina - seems to be scarce and limited. -FAU - Colantonio, Lisandro Damián -AU - Colantonio LD -AD - Institute for Clinical Effectiveness and Health Policy, Viamonte 2146, 3rd Floor, - C1056ABH, Buenos Aires, Argentina. lcolantonio@iecs.org.ar -FAU - Martí, Sebastián García -AU - Martí SG -FAU - Rubinstein, Adolfo Luis -AU - Rubinstein AL -LA - eng -GR - R24 TW007988/TW/FIC NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - England -TA - Expert Rev Pharmacoecon Outcomes Res -JT - Expert review of pharmacoeconomics & outcomes research -JID - 101132257 -SB - IM -MH - Argentina -MH - Cardiovascular Diseases/economics/*prevention & control -MH - Cost-Benefit Analysis -MH - Evidence-Based Medicine -MH - *Health Care Costs -MH - Humans -MH - Models, Economic -MH - Preventive Health Services/*economics -MH - Treatment Outcome -EDAT- 2010/08/19 06:00 -MHDA- 2010/12/14 06:00 -CRDT- 2010/08/19 06:00 -PHST- 2010/08/19 06:00 [entrez] -PHST- 2010/08/19 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -AID - 10.1586/erp.10.50 [doi] -PST - ppublish -SO - Expert Rev Pharmacoecon Outcomes Res. 2010 Aug;10(4):465-73. doi: - 10.1586/erp.10.50. - -PMID- 23917810 -OWN - NLM -STAT- MEDLINE -DCOM- 20140422 -LR - 20220309 -IS - 1534-3111 (Electronic) -IS - 1522-6417 (Linking) -VI - 15 -IP - 5 -DP - 2013 Oct -TI - Aldosterone synthase inhibition in hypertension. -PG - 484-8 -LID - 10.1007/s11906-013-0379-7 [doi] -AB - Hypertension is an established risk factor for stroke, premature coronary artery - disease and heart failure. Control of elevated blood pressure has been shown to - result in significant reduction of cardiovascular risk. Aldosterone, the final - product of the renin-angiotensin-aldosterone system (RAAS), not only causes salt - and water reabsorbtion in the kidneys through its effect on the mineralocorticoid - hormone receptor (MR), but also an MR-independent effect, not regulated by - conventional MR blockade. Although many pharmacological agents target different - levels of the RAAS cascade, these generally result in elevated renin - concentration and plasma renin activity. This upstream feedback response - subsequently results in elevated levels of angiotensin II, a potent - vasoconstrictor and stimulus to aldosterone release. This aldosterone - breakthrough counteracts the long-term blood pressure-lowering effect of these - agents. Therefore the development of a new class of pharmacologic agents that - directly inhibit the production of aldosterone may prove clinically useful in - reducing aldosterone and thereby controlling elevated blood pressure. -FAU - Andersen, Karl -AU - Andersen K -AD - Cardiovascular Research Center, Landspitali the University Hospital of Iceland, - IS-101, Reykjavik, Iceland, andersen@landspitali.is. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Hypertens Rep -JT - Current hypertension reports -JID - 100888982 -RN - 0 (Antihypertensive Agents) -RN - 0 (Enzyme Inhibitors) -RN - 4964P6T9RB (Aldosterone) -RN - EC 1.14.15.4 (Cytochrome P-450 CYP11B2) -SB - IM -MH - Aldosterone/biosynthesis -MH - Animals -MH - Antihypertensive Agents/*therapeutic use -MH - Cytochrome P-450 CYP11B2/*antagonists & inhibitors -MH - Enzyme Inhibitors/*therapeutic use -MH - Humans -MH - Hypertension/*drug therapy/enzymology -MH - Renin-Angiotensin System -EDAT- 2013/08/07 06:00 -MHDA- 2014/04/23 06:00 -CRDT- 2013/08/07 06:00 -PHST- 2013/08/07 06:00 [entrez] -PHST- 2013/08/07 06:00 [pubmed] -PHST- 2014/04/23 06:00 [medline] -AID - 10.1007/s11906-013-0379-7 [doi] -PST - ppublish -SO - Curr Hypertens Rep. 2013 Oct;15(5):484-8. doi: 10.1007/s11906-013-0379-7. - -PMID- 22189665 -OWN - NLM -STAT- MEDLINE -DCOM- 20120203 -LR - 20111222 -IS - 1541-8243 (Electronic) -IS - 0038-4348 (Linking) -VI - 105 -IP - 1 -DP - 2012 Jan -TI - Secondary hyperparathyroidism: benign bystander or culpable contributor to - adverse health outcomes? -PG - 36-42 -LID - 10.1097/SMJ.0b013e31823c4155 [doi] -AB - Elevation in serum parathyroid hormone (PTH) often accompanies vitamin D - deficiency and renal impairment. PTH elevation in renal failure is viewed as an - unfavorable development. Evidence is increasing that PTH elevation may be - associated with increased morbidity and mortality. In many instances these PTH - effects appear to be independent of vitamin D status. PTH mediates its effects - through the ubiquitous type 1 PTH/PTH-related peptide receptor, which is notably - present in the cardiovascular system. Increased PTH may promote cardiovascular - disease through diminished cardiac contractility, enhanced coronary risk, and - cardiac valvular and vascular calcification. High PTH levels appear to be linked - to the metabolic syndrome and are aligned with hyperlipidemia, decreased insulin - sensitivity, and, perhaps, decreased insulin secretion. Increased PTH also is - associated with neuroendocrine activation, increased sympathetic activity, and - endothelial stress. The relation between PTH and vitamin D is complex and may - show significant threshold variations, especially when calcium intake, age, and - race are considered. Moreover, evidence is increasing that fragments of PTH may - not only be hormonally active but also may have opposing effects to PTH. Despite - these caveats, PTH values provide useful clinical diagnostic and prognostic - information in monitoring many chronic ailments such as heart and renal failure - and multiple sclerosis. -FAU - Peiris, Alan N -AU - Peiris AN -AD - Tennessee State University, Johnson City, TN, USA. Peiris@etsu.edu -FAU - Youssef, Dima -AU - Youssef D -FAU - Grant, William B -AU - Grant WB -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - South Med J -JT - Southern medical journal -JID - 0404522 -SB - IM -MH - Cardiovascular Diseases/etiology -MH - Humans -MH - Hyperparathyroidism, Secondary/*complications -EDAT- 2011/12/23 06:00 -MHDA- 2012/02/04 06:00 -CRDT- 2011/12/23 06:00 -PHST- 2011/12/23 06:00 [entrez] -PHST- 2011/12/23 06:00 [pubmed] -PHST- 2012/02/04 06:00 [medline] -AID - 00007611-201201000-00008 [pii] -AID - 10.1097/SMJ.0b013e31823c4155 [doi] -PST - ppublish -SO - South Med J. 2012 Jan;105(1):36-42. doi: 10.1097/SMJ.0b013e31823c4155. - -PMID- 17667454 -OWN - NLM -STAT- MEDLINE -DCOM- 20070906 -LR - 20070801 -IS - 0090-3493 (Print) -IS - 0090-3493 (Linking) -VI - 35 -IP - 8 Suppl -DP - 2007 Aug -TI - History of echocardiography and its future applications in medicine. -PG - S309-13 -AB - This review concisely presents the chronology of events that shaped the - development of echocardiography. The concept of "seeing" structures using "sound" - dates back to the 1920s, when ultrasound produced by piezoelectric crystals was - used to detect flaws in metals. In the early 1950s, Hertz and Edler described the - use of ultrasound for assessing mitral-valve disease. Subsequently, Harvey - Feigenbaum in the 1960s standardized the clinical use of M-mode echocardiography - for quantitative assessment of left-ventricular dimensions. The advent of - 2-dimensional echocardiography (1970s), pulsed Doppler (1970s), and color Doppler - (1980s) introduced new methods for routine assessment of cardiac anatomy and - hemodynamics at bedside. Flexible scopes and superior transducers further paved - the way to the application of transesophageal echocardiography. Tissue Doppler - and contrast echocardiography recently have emerged as important tools for - evaluation of regional myocardial function and blood flow. Miniaturization and - the ability to pack thousands of crystals in an electronic array have transformed - the application of 3-dimensional echocardiography into a bedside tomographic - tool. At the current pace of development, echocardiography will be able to - provide complete assessment of the heart in terms of its anatomy, coronary flow, - and physiology. Training people and making it available at every bedside may be - the only remaining challenges. -FAU - Krishnamoorthy, Vijay K -AU - Krishnamoorthy VK -AD - Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA. -FAU - Sengupta, Partho P -AU - Sengupta PP -FAU - Gentile, Federico -AU - Gentile F -FAU - Khandheria, Bijoy K -AU - Khandheria BK -LA - eng -PT - Historical Article -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Med -JT - Critical care medicine -JID - 0355501 -SB - IM -MH - Echocardiography/*history -MH - Echocardiography, Doppler/history -MH - Echocardiography, Three-Dimensional/history -MH - History, 18th Century -MH - History, 19th Century -MH - History, 20th Century -MH - History, 21st Century -MH - Humans -RF - 50 -EDAT- 2007/08/19 09:00 -MHDA- 2007/09/07 09:00 -CRDT- 2007/08/19 09:00 -PHST- 2007/08/19 09:00 [pubmed] -PHST- 2007/09/07 09:00 [medline] -PHST- 2007/08/19 09:00 [entrez] -AID - 00003246-200708001-00001 [pii] -AID - 10.1097/01.CCM.0000270240.97375.DE [doi] -PST - ppublish -SO - Crit Care Med. 2007 Aug;35(8 Suppl):S309-13. doi: - 10.1097/01.CCM.0000270240.97375.DE. - -PMID- 23508767 -OWN - NLM -STAT- MEDLINE -DCOM- 20131119 -LR - 20211021 -IS - 1546-9549 (Electronic) -IS - 1546-9530 (Print) -IS - 1546-9530 (Linking) -VI - 10 -IP - 2 -DP - 2013 Jun -TI - Cardiac lipotoxicity: molecular pathways and therapeutic implications. -PG - 109-21 -LID - 10.1007/s11897-013-0133-0 [doi] -AB - Diabetes and obesity are both associated with lipotoxic cardiomyopathy exclusive - of coronary artery disease and hypertension. Lipotoxicities have become a public - health concern and are responsible for a significant portion of clinical cardiac - disease. These abnormalities may be the result of a toxic metabolic shift to more - fatty acid and less glucose oxidation with concomitant accumulation of toxic - lipids. Lipids can directly alter cellular structures and activate downstream - pathways leading to toxicity. Recent data have implicated fatty acids and fatty - acyl coenzyme A, diacylglycerol, and ceramide in cellular lipotoxicity, which may - be caused by apoptosis, defective insulin signaling, endoplasmic reticulum - stress, activation of protein kinase C, MAPK activation, or modulation of PPARs. -FAU - Drosatos, Konstantinos -AU - Drosatos K -AD - Division of Preventive Medicine and Nutrition, Department of Medicine, Columbia - University College of Physicians & Surgeons, 630 West 168th Street, New York, NY - 10032, USA. kd2277@columbia.edu -FAU - Schulze, P Christian -AU - Schulze PC -LA - eng -GR - K23 HL095742/HL/NHLBI NIH HHS/United States -GR - K99 HL112853/HL/NHLBI NIH HHS/United States -GR - 1K99HL112853-01/HL/NHLBI NIH HHS/United States -GR - K23HL24534/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - Curr Heart Fail Rep -JT - Current heart failure reports -JID - 101196487 -RN - 0 (Fatty Acids) -SB - IM -MH - Apoptosis/physiology -MH - Cardiomyopathies/*etiology/metabolism/pathology -MH - Diabetes Complications/*metabolism -MH - Fatty Acids/metabolism -MH - Humans -MH - Lipid Metabolism/physiology -MH - Obesity/*complications/metabolism -MH - Oxidation-Reduction -PMC - PMC3647019 -MID - NIHMS457596 -COIS- Disclosure Konstantinos Drosatos declares that he has no conflict of interest. P. - Christian Schulze declares that he has no conflict of interest. -EDAT- 2013/03/20 06:00 -MHDA- 2013/11/20 06:00 -PMCR- 2014/06/01 -CRDT- 2013/03/20 06:00 -PHST- 2013/03/20 06:00 [entrez] -PHST- 2013/03/20 06:00 [pubmed] -PHST- 2013/11/20 06:00 [medline] -PHST- 2014/06/01 00:00 [pmc-release] -AID - 10.1007/s11897-013-0133-0 [doi] -PST - ppublish -SO - Curr Heart Fail Rep. 2013 Jun;10(2):109-21. doi: 10.1007/s11897-013-0133-0. - -PMID- 21135595 -OWN - NLM -STAT- MEDLINE -DCOM- 20110322 -LR - 20161125 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 19 -IP - 1 -DP - 2011 Jan-Feb -TI - Effects of obesity and subsequent weight reduction on left ventricular function. -PG - 1-4 -LID - 10.1097/CRD.0b013e3181f877d2 [doi] -AB - Obesity is reaching epidemic proportions in the United States. Obesity adversely - affects the circulatory system with resultant endothelial dysfunction, which - promotes systemic hypertension, coronary artery disease, and vascular - calcification. It is believed that the release of adipokines is responsible for - this effect. In addition, obesity causes intrinsic changes in the heart including - an increase in left ventricular (LV) mass, LV hypertrophy, LV dilatation, left - atrial dilatation, and diastolic, as well as systolic dysfunction in some cases. - The combination of increased adipose cells and an increase lean muscle mass in - obese patients results in high cardiac output and an accompanying increased - circulating volume leading to these adaptive changes. Weight loss by means of - caloric restriction or surgery results in favorable hemodynamic changes referred - to as "reverse remodeling." Regression of LV mass and chamber size has been shown - universally. However, some studies have failed to reveal improvement in diastolic - function possibly because of confounders such as nutritional deficiency that may - occur after weight loss surgery. Some evidence seems to suggest that the greatest - regression of LV mass and LV hypertrophy may occur when weight loss is combined - with beta-adrenergic blocker therapy (in those who have an indication for the - drug) when compared with other antihypertensive drugs versus weight loss alone. -FAU - Lakhani, Mohan -AU - Lakhani M -AD - Division of Cardiology, Albany Medical Center, Albany, NY 12204, USA. - LakhanM@mail.amc.edu -FAU - Fein, Steven -AU - Fein S -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -RN - 0 (Anti-Obesity Agents) -SB - IM -MH - Anti-Obesity Agents/therapeutic use -MH - Bariatric Surgery -MH - Echocardiography -MH - Humans -MH - Obesity/diagnostic imaging/*physiopathology/therapy -MH - *Ventricular Function, Left -MH - *Weight Loss -EDAT- 2010/12/08 06:00 -MHDA- 2011/03/23 06:00 -CRDT- 2010/12/08 06:00 -PHST- 2010/12/08 06:00 [entrez] -PHST- 2010/12/08 06:00 [pubmed] -PHST- 2011/03/23 06:00 [medline] -AID - 00045415-201101000-00001 [pii] -AID - 10.1097/CRD.0b013e3181f877d2 [doi] -PST - ppublish -SO - Cardiol Rev. 2011 Jan-Feb;19(1):1-4. doi: 10.1097/CRD.0b013e3181f877d2. - -PMID- 16788329 -OWN - NLM -STAT- MEDLINE -DCOM- 20060726 -LR - 20060621 -IS - 1538-4683 (Electronic) -IS - 1061-5377 (Linking) -VI - 14 -IP - 4 -DP - 2006 Jul-Aug -TI - Value of microvolt T-wave alternans for predicting patients who would benefit - from implantable cardioverter-defibrillator therapy. -PG - 173-9 -AB - Despite considerable progress in the management of coronary artery disease and - dilated cardiomyopathy, a substantial proportion of patients remains at the risk - of life-threatening arrhythmic events. The Multicenter Automatic Defibrillator - Implantation II and Sudden Cardiac Death Heart Failure studies have conclusively - demonstrated that prophylactic implantable cardioverter-defibrillator (ICD) - therapy reduces mortality among subjects with ischemic and nonischemic - cardiomyopathy but at the expense of potentially unnecessary ICD implantation in - a large percentage of patients. Microvolt T-wave alternans (MTWA), with a - negative predictive value greater than 90%, holds promise for selecting the - patients who would likely and patients not likely to benefit from ICD - implantation. Accurate identification of high-risk patients by noninvasive MTWA - may allow for improved widespread screening for sudden death prevention in the - general population. -FAU - Haghjoo, Majid -AU - Haghjoo M -AD - Department of Pacemaker and Electrophysiology, Rajaie Cardiovascular Medical and - Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, - Iran. majid.haghjoo@gmail.com -FAU - Arya, Arash -AU - Arya A -FAU - Sadr-Ameli, Mohammad Ali -AU - Sadr-Ameli MA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiol Rev -JT - Cardiology in review -JID - 9304686 -SB - IM -MH - Cardiomyopathy, Dilated/*physiopathology/*therapy -MH - Death, Sudden, Cardiac -MH - *Defibrillators, Implantable -MH - *Electrophysiologic Techniques, Cardiac -MH - Humans -MH - Predictive Value of Tests -MH - Risk Assessment -RF - 41 -EDAT- 2006/06/22 09:00 -MHDA- 2006/07/27 09:00 -CRDT- 2006/06/22 09:00 -PHST- 2006/06/22 09:00 [pubmed] -PHST- 2006/07/27 09:00 [medline] -PHST- 2006/06/22 09:00 [entrez] -AID - 00045415-200607000-00007 [pii] -AID - 10.1097/01.crd.0000184454.56306.d6 [doi] -PST - ppublish -SO - Cardiol Rev. 2006 Jul-Aug;14(4):173-9. doi: 10.1097/01.crd.0000184454.56306.d6. - -PMID- 28348697 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20201001 -IS - 1923-2829 (Print) -IS - 1923-2837 (Electronic) -IS - 1923-2829 (Linking) -VI - 4 -IP - 1 -DP - 2013 Feb -TI - Carotid Artery Stenting 2013: Thumbs up. -PG - 8-14 -LID - 10.4021/cr253w [doi] -AB - It has been customary for interventional cardiologists involved in carotid artery - stenting, to underline non-inferiority of the percutaneous technique versus - surgical carotid endarterectomy. To that end, all cause morbidity and mortality - figures of both methods are compared. Surgery has, in most large randomized - studies, had an edge over stenting in terms of cerebrovascular adverse events. - This may have partly been due to occasional indiscriminate indication for - stenting in lesions and/or vessels with unfavourable characteristics (severe - target vessel tortuosity and calcification, Type III aortic arch, and so on). On - one hand, the author pleads for improvement of the excellent results of - endarterectomy, by subjecting all patients planned for surgery to a thorough - preoperative cardiological work up, including generous invasive investigation, - thus reducing the incidence of perioperative myocardial infarction, heart failure - and cardiac death. On the other hand, we are convinced that the results of - carotid stenting should then be compared to best practice surgery. The rate of - neurological adverse event rate after carotid endarterectomy at our institution - lies under 0.7% at 30 days postoperatively. Specifically, the goal should be that - carotid stenting underbids surgical endarterectomy, also and mainly, in terms of - cerebral and cerebrovascular adverse events. Cardiac morbidity and mortality as - well as laryngeal nerve palsy should no more be the main arguments for the - percutaneous approach. This should easily be possible if patient selection for - carotid revascularisation would be approached according to morphological - criteria, in analogy with the "Syntax"-score used to optimise revascularisation - strategies in coronary artery disease. -FAU - Wagdi, Philipp -AU - Wagdi P -AD - Interventional Cardiology, HerzZentrum Hirslanden, Witellikerstrasse 36, 8008 - Zurich, Switzerland. Email: wagdi@herzzentrum.ch. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130308 -PL - Canada -TA - Cardiol Res -JT - Cardiology research -JID - 101557543 -PMC - PMC5358182 -OTO - NOTNLM -OT - Carotid artery stenosis -OT - Carotid artery stenting -OT - Carotid endarterectomy -OT - Stroke -EDAT- 2013/02/01 00:00 -MHDA- 2013/02/01 00:01 -PMCR- 2013/02/01 -CRDT- 2017/03/29 06:00 -PHST- 2013/02/19 00:00 [accepted] -PHST- 2017/03/29 06:00 [entrez] -PHST- 2013/02/01 00:00 [pubmed] -PHST- 2013/02/01 00:01 [medline] -PHST- 2013/02/01 00:00 [pmc-release] -AID - 10.4021/cr253w [doi] -PST - ppublish -SO - Cardiol Res. 2013 Feb;4(1):8-14. doi: 10.4021/cr253w. Epub 2013 Mar 8. - -PMID- 23219077 -OWN - NLM -STAT- MEDLINE -DCOM- 20140422 -LR - 20220408 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 167 -IP - 5 -DP - 2013 Sep 1 -TI - Cardiovascular involvement in patients affected by acromegaly: an appraisal. -PG - 1712-8 -LID - S0167-5273(12)01592-6 [pii] -LID - 10.1016/j.ijcard.2012.11.109 [doi] -AB - Cardiovascular complications are frequent in acromegalic patients. Several - studies reported increased prevalence of traditional cardiovascular risk factors - and early development of endothelial dysfunction and of structural vascular - alterations, with subsequent increased risk of coronary artery disease. - Furthermore, chronic exposure to high levels of GH and IGF-I leads to the - development of the so called "acromegalic cardiomyopathy", characterized by - concentric biventricular hypertrophy, diastolic dysfunction and, additionally, by - progressive impairment of systolic performance leading to overt heart failure. - Cardiac valvulopathies and arrhythmias have also been documented and may concur - to the deterioration of cardiac function. Together with strict control of - cardiovascular risk factors, early control of GH and IGF-I excess, by surgical or - pharmacological therapy, has been reported to ameliorate cardiac and metabolic - abnormalities, leading to a significant reduction of left ventricular hypertrophy - and to a consistent improvement of cardiac performance. -CI - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved. -FAU - Mosca, Susanna -AU - Mosca S -AD - Department of Advanced Biomedical Sciences, University of Naples Federico II, - Naples, Italy. -FAU - Paolillo, Stefania -AU - Paolillo S -FAU - Colao, Annamaria -AU - Colao A -FAU - Bossone, Eduardo -AU - Bossone E -FAU - Cittadini, Antonio -AU - Cittadini A -FAU - Iudice, Francesco Lo -AU - Iudice FL -FAU - Parente, Antonio -AU - Parente A -FAU - Conte, Sirio -AU - Conte S -FAU - Rengo, Giuseppe -AU - Rengo G -FAU - Leosco, Dario -AU - Leosco D -FAU - Trimarco, Bruno -AU - Trimarco B -FAU - Filardi, Pasquale Perrone -AU - Filardi PP -LA - eng -PT - Journal Article -PT - Review -DEP - 20121204 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 12629-01-5 (Human Growth Hormone) -SB - IM -MH - Acromegaly/*diagnosis/epidemiology/*physiopathology -MH - Animals -MH - Cardiovascular Diseases/*diagnosis/epidemiology/*physiopathology -MH - *Cardiovascular Physiological Phenomena -MH - Human Growth Hormone/metabolism -MH - Humans -MH - Risk Factors -OTO - NOTNLM -OT - Acromegalic cardiomyopathy -OT - Acromegaly -OT - GH/IGF-I excess -OT - Premature atherosclerosis -EDAT- 2012/12/12 06:00 -MHDA- 2014/04/23 06:00 -CRDT- 2012/12/11 06:00 -PHST- 2012/07/02 00:00 [received] -PHST- 2012/10/01 00:00 [revised] -PHST- 2012/11/13 00:00 [accepted] -PHST- 2012/12/11 06:00 [entrez] -PHST- 2012/12/12 06:00 [pubmed] -PHST- 2014/04/23 06:00 [medline] -AID - S0167-5273(12)01592-6 [pii] -AID - 10.1016/j.ijcard.2012.11.109 [doi] -PST - ppublish -SO - Int J Cardiol. 2013 Sep 1;167(5):1712-8. doi: 10.1016/j.ijcard.2012.11.109. Epub - 2012 Dec 4. - -PMID- 22562742 -OWN - NLM -STAT- MEDLINE -DCOM- 20130116 -LR - 20181201 -IS - 1439-3964 (Electronic) -IS - 0172-4622 (Linking) -VI - 33 -IP - 9 -DP - 2012 Sep -TI - Cardiovascular effects of exercise in young hypertensives. -PG - 683-90 -LID - 10.1055/s-0032-1304633 [doi] -AB - Sedentary habits are largely responsible for the alarming rise in the prevalence - of hypertension among young individuals. Regular aerobic exercise has been shown - to reduce not only blood pressure (BP) in resting conditions but also BP - reactivity to stressors. Much less is known about the long-term effects of - physical activity on target organ damage in hypertension. Some studies have - documented that exercise is able to decrease rather than increase left - ventricular mass and that even competitive athletics have beneficial effects on - the heart. In addition, physical activity during leisure has been found to be - inversely associated with the progression of subclinical atherosclerosis and to - delay aging dependent arterial stiffness. Isolated systolic hypertension in - physically active young people is often an innocent clinical condition caused by - an elevated pulse pressure amplification and low wave arterial reflection from - peripheral sites, due to increased arterial elasticity. The above findings - support a strategy of exercise training as an initial approach in the management - of young sedentary patients in the early stages of hypertension. Caution should - be used in subjects with more severe hypertension and every hypertensive athlete - should be thoroughly investigated to exclude target organ damage and coronary - artery disease. -CI - © Georg Thieme Verlag KG Stuttgart · New York. -FAU - Palatini, P -AU - Palatini P -AD - Department of Medicine, University of Padova, Padua, Italy. palatini@unipd.it -LA - eng -PT - Journal Article -PT - Review -DEP - 20120504 -PL - Germany -TA - Int J Sports Med -JT - International journal of sports medicine -JID - 8008349 -SB - IM -MH - Age Factors -MH - Blood Pressure/physiology -MH - Cardiovascular Diseases/etiology/*prevention & control -MH - Exercise/*physiology -MH - Humans -MH - Hypertension/complications/epidemiology/*therapy -MH - Motor Activity/physiology -MH - Prevalence -MH - Sedentary Behavior -MH - Severity of Illness Index -MH - Time Factors -EDAT- 2012/05/09 06:00 -MHDA- 2013/01/17 06:00 -CRDT- 2012/05/08 06:00 -PHST- 2012/05/08 06:00 [entrez] -PHST- 2012/05/09 06:00 [pubmed] -PHST- 2013/01/17 06:00 [medline] -AID - 10.1055/s-0032-1304633 [doi] -PST - ppublish -SO - Int J Sports Med. 2012 Sep;33(9):683-90. doi: 10.1055/s-0032-1304633. Epub 2012 - May 4. - -PMID- 22497050 -OWN - NLM -STAT- MEDLINE -DCOM- 20120503 -LR - 20151119 -IS - 0019-4832 (Print) -IS - 0019-4832 (Linking) -VI - 63 -IP - 4 -DP - 2011 Jul-Aug -TI - How to approach sudden cardiac arrest: current knowledge and clinical practice. -PG - 341-6 -AB - SCA is a dynamic and unexpected event that remains a major and global public - health problem. There can be multiple etiologies but coronary artery disease - remains the major player. The initial approach to SCA requires a rapid - community-based response. Specific guidelines are available for provision of - pre-hospital care and methodology continues to evolve. However, even with rapid - response, survival from SCA is extremely low and there is significant regional - variation. For SCA victims that survive to reach the hospital, a careful - step-wise approach to immediate care and subsequent identification of SCA - etiology is advisable. While primary prevention for sudden death has come a long - way, significant enhancement of risk stratification techniques is needed to - maximize benefit and efficiency of health care utilization. The persisting low - survival rates following SCA continue to emphasize that achievement of efficient - risk stratification and primary prevention must remain our major target for - management of SCA. -FAU - Chugh, Sumeet S -AU - Chugh SS -AD - The Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. - sumeet.chugh@cshs.org -LA - eng -GR - R01HL088416/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - India -TA - Indian Heart J -JT - Indian heart journal -JID - 0374675 -SB - IM -MH - Cardiology/trends -MH - Death, Sudden, Cardiac/*prevention & control -MH - Forecasting -MH - Hospitalization/trends -MH - Humans -MH - Practice Patterns, Physicians'/trends -MH - Risk -MH - United States -EDAT- 2012/04/14 06:00 -MHDA- 2012/05/04 06:00 -CRDT- 2012/04/14 06:00 -PHST- 2012/04/14 06:00 [entrez] -PHST- 2012/04/14 06:00 [pubmed] -PHST- 2012/05/04 06:00 [medline] -PST - ppublish -SO - Indian Heart J. 2011 Jul-Aug;63(4):341-6. - -PMID- 19693019 -OWN - NLM -STAT- MEDLINE -DCOM- 20100125 -LR - 20091110 -IS - 1476-5489 (Electronic) -IS - 0955-9930 (Linking) -VI - 21 -IP - 6 -DP - 2009 Nov-Dec -TI - How to save a life during a clinic visit for erectile dysfunction by modifying - cardiovascular risk factors. -PG - 327-35 -LID - 10.1038/ijir.2009.38 [doi] -AB - Erectile dysfunction (ED) is an early marker for systemic atherosclerosis and is - a predictor for coronary artery disease and cardiac events. The aim of this paper - is to convey the importance of addressing cardiovascular risk factors in patients - with ED and to inform urologists as well as other physicians who are not - specialized in cardiology how to carry out a basic cardiovascular evaluation, - including history, physical examination and objective data. We review the - evidence and pathophysiology linking ED to cardiovascular disease, and then - describe how to carry out a basic cardiovascular evaluation. We present data from - the literature showing that appropriate use of lifestyle modifications and - medical therapy has a positive effect on mortality, on numerous cardiovascular - end points and on ED. Suggestions of when to refer the ED patient to an internist - or cardiologist are provided. Identifying and treating cardiovascular risk - factors may not only benefit the patient's ED, but it might also save the - patient's life. -FAU - Schwartz, B G -AU - Schwartz BG -AD - Heart Institute, Good Samaritan Hospital, Los Angeles, CA 90017-2395, USA. -FAU - Kloner, R A -AU - Kloner RA -LA - eng -PT - Journal Article -PT - Review -DEP - 20090820 -PL - England -TA - Int J Impot Res -JT - International journal of impotence research -JID - 9007383 -SB - IM -MH - Ambulatory Care -MH - Atherosclerosis/epidemiology/prevention & control -MH - Cardiovascular Diseases/drug therapy/*epidemiology/*prevention & control -MH - Erectile Dysfunction/drug therapy/physiopathology/*therapy -MH - Humans -MH - Life Style -MH - Male -MH - *Patient Education as Topic -MH - Penile Erection/physiology -MH - Risk Factors -RF - 62 -EDAT- 2009/08/21 09:00 -MHDA- 2010/01/26 06:00 -CRDT- 2009/08/21 09:00 -PHST- 2009/08/21 09:00 [entrez] -PHST- 2009/08/21 09:00 [pubmed] -PHST- 2010/01/26 06:00 [medline] -AID - ijir200938 [pii] -AID - 10.1038/ijir.2009.38 [doi] -PST - ppublish -SO - Int J Impot Res. 2009 Nov-Dec;21(6):327-35. doi: 10.1038/ijir.2009.38. Epub 2009 - Aug 20. - -PMID- 18158472 -OWN - NLM -STAT- MEDLINE -DCOM- 20080215 -LR - 20071225 -IS - 1530-0293 (Electronic) -IS - 0090-3493 (Linking) -VI - 36 -IP - 1 Suppl -DP - 2008 Jan -TI - Practical recommendations for prehospital and early in-hospital management of - patients presenting with acute heart failure syndromes. -PG - S129-39 -LID - 10.1097/01.CCM.0000296274.51933.4C [doi] -AB - Guideline recommendations for the prehospital and early in-hospital (first 6-12 - hrs after presentation) management of acute heart failure syndromes are lacking. - The American College of Cardiology/American Heart Association and European - Society of Cardiology guidelines direct the management of these acute heart - failure patients, but specific consensus on early management has not been - published, primarily because few early management trials have been conducted. - This article summarizes practical recommendations for the prehospital and early - management of patients with acute heart failure syndromes; the recommendations - were developed from a meeting of experts in cardiology, emergency medicine, and - intensive care medicine from Europe and the United States. The recommendations - are based on a unique clinical classification system considering the initial - systolic blood pressure and other symptoms: 1) dyspnea and/or congestion with - systolic blood pressure >140 mm Hg; 2) dyspnea and/or congestion with systolic - blood pressure 100-140 mm Hg; 3) dyspnea and/or congestion with systolic blood - pressure <100 mm Hg; 4) dyspnea and/or congestion with signs of acute coronary - syndrome; and 5) isolated right ventricular failure. These practical - recommendations are not intended to replace existing guidelines. Rather, they are - meant to serve as a tool to facilitate guideline implementation where data are - available and to provide suggested treatment approaches where formal guidelines - and definitive evidence are lacking. -FAU - Mebazaa, Alexandre -AU - Mebazaa A -AD - Hôpital Lariboisière APHP, University Paris 7 Diderot, Paris, France. - alexandre.mebazaa@lrb.aphp.fr -FAU - Gheorghiade, Mihai -AU - Gheorghiade M -FAU - Piña, Ileana L -AU - Piña IL -FAU - Harjola, Veli-Pekka -AU - Harjola VP -FAU - Hollenberg, Steven M -AU - Hollenberg SM -FAU - Follath, Ferenc -AU - Follath F -FAU - Rhodes, Andrew -AU - Rhodes A -FAU - Plaisance, Patrick -AU - Plaisance P -FAU - Roland, Edmond -AU - Roland E -FAU - Nieminen, Markku -AU - Nieminen M -FAU - Komajda, Michel -AU - Komajda M -FAU - Parkhomenko, Alexander -AU - Parkhomenko A -FAU - Masip, Josep -AU - Masip J -FAU - Zannad, Faiez -AU - Zannad F -FAU - Filippatos, Gerasimos -AU - Filippatos G -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Med -JT - Critical care medicine -JID - 0355501 -RN - 0 (Cardiotonic Agents) -RN - 0 (Diuretics) -RN - 0 (Vasoconstrictor Agents) -RN - 0 (Vasodilator Agents) -SB - IM -MH - Acute Disease -MH - Algorithms -MH - Blood Pressure -MH - Cardiotonic Agents/therapeutic use -MH - Diuretics/*therapeutic use -MH - Dyspnea/etiology -MH - Emergency Medical Services -MH - Heart Failure/complications/diagnosis/physiopathology/*therapy -MH - Humans -MH - Practice Guidelines as Topic -MH - Respiration, Artificial -MH - Vasoconstrictor Agents/therapeutic use -MH - Vasodilator Agents/*therapeutic use -RF - 72 -EDAT- 2008/02/15 09:00 -MHDA- 2008/02/19 09:00 -CRDT- 2008/02/15 09:00 -PHST- 2008/02/15 09:00 [pubmed] -PHST- 2008/02/19 09:00 [medline] -PHST- 2008/02/15 09:00 [entrez] -AID - 00003246-200801001-00017 [pii] -AID - 10.1097/01.CCM.0000296274.51933.4C [doi] -PST - ppublish -SO - Crit Care Med. 2008 Jan;36(1 Suppl):S129-39. doi: - 10.1097/01.CCM.0000296274.51933.4C. - -PMID- 23016716 -OWN - NLM -STAT- MEDLINE -DCOM- 20130816 -LR - 20180605 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 19 -IP - 9 -DP - 2013 -TI - Targeting myocardial metabolism for the treatment of stable angina. -PG - 1587-92 -AB - The goals of pharmacological treatment of stable angina pectoris are to improve - quality of life by reducing the severity and/or frequency of symptoms and also - the long-term prognosis. Patients with coronary artery disease have viable but - dysfunctional myocardium. The metabolism of the ischemic myocardium is - characterized by a shift from fatty acid to glucose as a preferred substrate and - a decline in the levels of ATP. Targeting myocardial metabolism as a - pharmacologic approach for chronic angina is based on the concept that metabolic - adaptive mechanisms during ischemia resemble fetal energy metabolism by shifting - substrate use towards glucose metabolism. Potential pharmacologic approaches - should target i) the suppression of lipolysis and the plasma fatty acid levels - and subsequent uptake and oxidation by the heart, ii) direct inhibition of the - enzymes of fatty acid beta-oxidation, iii) inhibition of carnitine palmitoyl - transferase- I (CPT-1). Currently, there are no approved medications directly - targeting myocardial metabolism. However, in the last two years a number of - medications indirectly targeting cardiac metabolism have been tested in small - clinical trials, and some of them appear to be promising potential therapies for - stable angina. This review summarizes the main aspects of myocardial metabolism - and focuses on the therapeutic approaches that could offer clinical benefit in - patients with stable angina. -FAU - Tousoulis, Dimitris -AU - Tousoulis D -AD - 1st Cardiology Unit, Athens University Medical School, Greece. - drtousoulis@hotmail.com -FAU - Bakogiannis, Constantinos -AU - Bakogiannis C -FAU - Briasoulis, Alexandros -AU - Briasoulis A -FAU - Papageorgiou, Nikolaos -AU - Papageorgiou N -FAU - Androulakis, Emmanuel -AU - Androulakis E -FAU - Siasos, Gerasimos -AU - Siasos G -FAU - Latsios, George -AU - Latsios G -FAU - Kampoli, Anna-Maria -AU - Kampoli AM -FAU - Charakida, Marietta -AU - Charakida M -FAU - Toutouzas, Kostas -AU - Toutouzas K -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 8L70Q75FXE (Adenosine Triphosphate) -SB - IM -MH - Adenosine Triphosphate/metabolism -MH - Angina Pectoris/metabolism/*therapy -MH - Humans -MH - Myocardium/*metabolism -EDAT- 2012/09/29 06:00 -MHDA- 2013/08/21 06:00 -CRDT- 2012/09/29 06:00 -PHST- 2012/08/31 00:00 [received] -PHST- 2012/09/17 00:00 [accepted] -PHST- 2012/09/29 06:00 [entrez] -PHST- 2012/09/29 06:00 [pubmed] -PHST- 2013/08/21 06:00 [medline] -AID - CPD-EPUB-20120918-5 [pii] -PST - ppublish -SO - Curr Pharm Des. 2013;19(9):1587-92. - -PMID- 23993002 -OWN - NLM -STAT- MEDLINE -DCOM- 20140520 -LR - 20250104 -IS - 0019-4832 (Print) -IS - 0019-4832 (Linking) -VI - 65 -IP - 4 -DP - 2013 Jul-Aug -TI - ST segment elevations: always a marker of acute myocardial infarction? -PG - 412-23 -LID - S0019-4832(13)00193-4 [pii] -LID - 10.1016/j.ihj.2013.06.013 [doi] -AB - Chest pain is one of the chief presenting complaints among patients attending - Emergency department. The diagnosis of acute myocardial infarction may be a - challenge. Various tools such as anamnesis, blood sample (with evaluation of - markers of myocardial necrosis), ultrasound techniques and coronary computed - tomography could be useful. However, the interpretation of electrocardiograms of - these patients may be a real concern. The earliest manifestations of myocardial - ischemia typically interest T waves and ST segment. Despite the high sensitivity, - ST segment deviation has however poor specificity since it may be observed in - many other cardiac and non-cardiac conditions. Therefore, when ST-T abnormalities - are detected the physicians should take into account many other parameters (such - as risk factors, symptoms and anamnesis) and all the other differential - diagnoses. The aim of our review is to overview of the main conditions that may - mimic a ST segment Elevation Myocardial Infarction (STEMI). -CI - Copyright © 2013 Cardiological Society of India. Published by Elsevier B.V. All - rights reserved. -FAU - Coppola, G -AU - Coppola G -AD - O.U. of Cardiology, A.O.U. Policlinico "P. Giaccone", University of Palermo, - Italy. -FAU - Carità, P -AU - Carità P -FAU - Corrado, E -AU - Corrado E -FAU - Borrelli, A -AU - Borrelli A -FAU - Rotolo, A -AU - Rotolo A -FAU - Guglielmo, M -AU - Guglielmo M -FAU - Nugara, C -AU - Nugara C -FAU - Ajello, L -AU - Ajello L -FAU - Santomauro, M -AU - Santomauro M -FAU - Novo, S -AU - Novo S -CN - Italian Study Group of Cardiovascular Emergencies of the Italian Society of - Cardiology -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian Heart J -JT - Indian heart journal -JID - 0374675 -SB - IM -MH - Arrhythmias, Cardiac/diagnosis/physiopathology -MH - Brugada Syndrome -MH - Cardiac Conduction System Disease -MH - Cardiovascular Diseases/diagnosis/physiopathology -MH - Chest Pain/diagnosis/physiopathology -MH - Diagnosis, Differential -MH - *Electrocardiography -MH - Gastrointestinal Diseases/diagnosis/physiopathology -MH - Heart Conduction System/abnormalities/physiopathology -MH - Humans -MH - Lung Diseases/diagnosis/physiopathology -MH - Myocardial Infarction/*diagnosis/*physiopathology -PMC - PMC3860734 -OTO - NOTNLM -OT - Chest pain -OT - Differential diagnosis -OT - ECG -OT - Myocardial infarction -OT - ST segment -EDAT- 2013/09/03 06:00 -MHDA- 2014/05/21 06:00 -PMCR- 2013/07/01 -CRDT- 2013/09/03 06:00 -PHST- 2012/12/17 00:00 [received] -PHST- 2013/06/19 00:00 [accepted] -PHST- 2013/09/03 06:00 [entrez] -PHST- 2013/09/03 06:00 [pubmed] -PHST- 2014/05/21 06:00 [medline] -PHST- 2013/07/01 00:00 [pmc-release] -AID - S0019-4832(13)00193-4 [pii] -AID - 10.1016/j.ihj.2013.06.013 [doi] -PST - ppublish -SO - Indian Heart J. 2013 Jul-Aug;65(4):412-23. doi: 10.1016/j.ihj.2013.06.013. - -PMID- 22644698 -OWN - NLM -STAT- MEDLINE -DCOM- 20121231 -LR - 20161020 -IS - 1573-7241 (Electronic) -IS - 0920-3206 (Linking) -VI - 26 -IP - 4 -DP - 2012 Aug -TI - The use of ω-3 poly-unsaturated fatty acids in heart failure: a preferential role - in patients with diabetes. -PG - 311-20 -LID - 10.1007/s10557-012-6397-x [doi] -AB - PURPOSE: To review the evidence for a beneficial effect of ω-3 PUFAs in heart - failure (HF) and its co-morbidities, their possible preferential effect in - diabetes and the potential mechanism for their benefit. METHODS: We summarize the - clinical studies which investigated the use of ω-3 PUFAs in patients with HF with - an emphasis on diabetes. We briefly summarize the evidence for an effect of ω-3 - PUFAs in patients with coronary artery disease (CAD), atrial fibrillation (AF) - and ventricular arrhythmias. We also discuss the proposed mechanisms of ω-3 PUFA - action in cardiovascular diseases. RESULTS: While there is emerging evidence for - a beneficial effect of ω-3 PUFA supplementation in patients with HF, the evidence - for other indications have been variable and conflicting. In HF patients with - diabetes, ω-3 PUFAs may have a preferential therapeutic benefit. Randomized - controlled trials did not show considerable beneficial effects of ω-3 PUFAs in - other conditions such as CAD and AF. In a diabetic and insulin-resistant state, - ω-3 PUFAs bind to the G-protein coupled receptor, GPR120, resulting in reduced - cytokine production from inflammatory macrophages and improved signaling in - adipocytes, leading to a reduction in insulin resistance. CONCLUSIONS: There is - promising evidence showing that use of ω-3 PUFA supplementation improves clinical - outcomes of HF patients with diabetes. Further clinical trials are needed in this - regard. -FAU - Kazemian, Pedram -AU - Kazemian P -AD - Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart - Institute, University of Alberta, Edmonton, Canada. -FAU - Kazemi-Bajestani, Seyyed M R -AU - Kazemi-Bajestani SM -FAU - Alherbish, Aws -AU - Alherbish A -FAU - Steed, Justin -AU - Steed J -FAU - Oudit, Gavin Y -AU - Oudit GY -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiovasc Drugs Ther -JT - Cardiovascular drugs and therapy -JID - 8712220 -RN - 0 (Fatty Acids, Omega-3) -RN - 0 (Fatty Acids, Unsaturated) -SB - IM -MH - Diabetes Complications/*drug therapy -MH - Diabetes Mellitus/*drug therapy -MH - Fatty Acids, Omega-3/*pharmacology -MH - Fatty Acids, Unsaturated/*pharmacology -MH - Heart Failure/*drug therapy -MH - Humans -MH - Randomized Controlled Trials as Topic -EDAT- 2012/05/31 06:00 -MHDA- 2013/01/01 06:00 -CRDT- 2012/05/31 06:00 -PHST- 2012/05/31 06:00 [entrez] -PHST- 2012/05/31 06:00 [pubmed] -PHST- 2013/01/01 06:00 [medline] -AID - 10.1007/s10557-012-6397-x [doi] -PST - ppublish -SO - Cardiovasc Drugs Ther. 2012 Aug;26(4):311-20. doi: 10.1007/s10557-012-6397-x. - -PMID- 23766358 -OWN - NLM -STAT- MEDLINE -DCOM- 20140611 -LR - 20130813 -IS - 1940-4034 (Electronic) -IS - 1074-2484 (Linking) -VI - 18 -IP - 5 -DP - 2013 Sep -TI - Traditional heart failure medications and sudden cardiac death prevention: a - review. -PG - 412-26 -LID - 10.1177/1074248413491496 [doi] -AB - Sudden cardiac death (SCD) is still a major public health issue with an estimated - annual incidence ranging from 184,000 to > 400,000 per year. The ACC/AHA/ESC 2006 - guidelines define SCD as "death from an unexpected circulatory arrest, usually - due to a cardiac arrhythmia occurring within an hour of the onset of symptoms". A - recent study of sudden cardiac death using multiple sources of ascertainment - found that coronary artery disease was present in more than 50% of patients older - than 35 years who died suddenly and underwent autopsy. Antiarrhythmic drugs have - failed to show any mortality benefit even when compared to placebo or implantable - cardiovertor defibrillators (ICDs). While patients with systolic heart failure - are at higher risk of dying suddenly, most of the patients experiencing sudden - cardiac death have left ventricular ejection fraction (LVEF) > 50%. β-blockers, - Angiotensin enzymes (ACE) inhibitors as well as aldosterone antagonists prevent - ischemia and remodelling in the left ventricle especially in post myocardial - infarction (MI) patients and in patients with systolic heart failure. This - article will review the data on the effects of traditional heart failure - medications, especially β-blockers, Renin Angiotensin system blockers, as well as - Statin therapy on sudden cardiac death in post MI patients and in patients with - systolic heart failure. -FAU - Al Chekakie, M Obadah -AU - Al Chekakie MO -AD - Cheyenne Regional Medical Center, University of Colorado, Cheyenne, Wyoming, WY - 82001, USA. obadac@gmail.com -LA - eng -PT - Journal Article -PT - Review -DEP - 20130613 -PL - United States -TA - J Cardiovasc Pharmacol Ther -JT - Journal of cardiovascular pharmacology and therapeutics -JID - 9602617 -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Animals -MH - Anti-Arrhythmia Agents/pharmacology/therapeutic use -MH - Cardiovascular Agents/pharmacology/*therapeutic use -MH - Death, Sudden, Cardiac/epidemiology/*prevention & control -MH - Defibrillators, Implantable -MH - Heart Failure/complications/*drug therapy/physiopathology -MH - Humans -MH - Incidence -MH - Practice Guidelines as Topic -OTO - NOTNLM -OT - heart failure -OT - renin–angiotensin–aldosterone system -OT - statin -OT - sudden cardiac death -EDAT- 2013/06/15 06:00 -MHDA- 2014/06/12 06:00 -CRDT- 2013/06/15 06:00 -PHST- 2013/06/15 06:00 [entrez] -PHST- 2013/06/15 06:00 [pubmed] -PHST- 2014/06/12 06:00 [medline] -AID - 1074248413491496 [pii] -AID - 10.1177/1074248413491496 [doi] -PST - ppublish -SO - J Cardiovasc Pharmacol Ther. 2013 Sep;18(5):412-26. doi: - 10.1177/1074248413491496. Epub 2013 Jun 13. - -PMID- 17035509 -OWN - NLM -STAT- MEDLINE -DCOM- 20070417 -LR - 20181113 -IS - 1468-201X (Electronic) -IS - 1355-6037 (Print) -IS - 1355-6037 (Linking) -VI - 93 -IP - 3 -DP - 2007 Mar -TI - Antithrombotic treatment for peripheral arterial disease. -PG - 303-8 -AB - CONTEXT: Patients with peripheral arterial disease (PAD) bear a substantial risk - for vascular events in the coronary, cerebral and peripheral circulations. In - addition, this disorder is associated with a systemic milieu characterised by - ongoing platelet activation and heightened thrombogenesis. OBJECTIVE: To - determine the optimal antithrombotic prophylaxis for patients with PAD. DATA - SOURCES: Using terms related to PAD and antithrombotic agents, we searched the - following databases for relevant articles: MEDLINE, EMBASE, the Cochrane Central - Register of Controlled Trials, the Cochrane Database of Systematic Reviews, the - National Institutes of Health Clinical Trials Database, Web of Science, and the - International Pharmaceutical Abstracts Database (search dates: 1 January 1990 to - 1 January 2007). Additional articles were identified from cardiovascular and - vascular surgery conference proceedings, bibliographies of review articles, and - personal files. STUDY SELECTION: We focused on randomised trials, systematic - reviews and consensus guidelines of antithrombotic therapies for PAD. DATA - EXTRACTION: Detailed study information was abstracted by each author working - independently. RESULTS: Multiple studies show that patients with PAD manifest - platelet hyperaggregability, increased levels of soluble platelet activation - markers, enhanced thrombin generation and altered fibrinolytic potential. Many of - these markers predict subsequent cardiovascular events. Available randomised - trials and meta-analyses show that most available antithrombotic agents prevent - major cardiovascular events and death in patients with PAD, including aspirin, - aspirin/dipyridamole, clopidogrel, ticlopidine, picotamide and oral - anticoagulants. CONCLUSIONS: Although the most favourable risk-benefit profile, - cost-effectiveness and overall evidence base supports aspirin in this setting, we - provide scenarios in which alternatives to aspirin should be considered. -FAU - Hackam, Daniel G -AU - Hackam DG -AD - Division of Clinical Pharmacology and Toxicology, University of Toronto, Toronto, - Canada. Daniel.Hackam@ices.on.ca -FAU - Eikelboom, John W -AU - Eikelboom JW -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20061011 -PL - England -TA - Heart -JT - Heart (British Cardiac Society) -JID - 9602087 -RN - 0 (Anticoagulants) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Pyridines) -RN - 0 (Thromboxanes) -RN - 0 (thienopyridine) -SB - IM -MH - Anticoagulants/*therapeutic use -MH - Fibrinolytic Agents/*therapeutic use -MH - Forecasting -MH - Humans -MH - Peripheral Vascular Diseases/*drug therapy -MH - Pyridines/therapeutic use -MH - Thromboxanes/antagonists & inhibitors -PMC - PMC1861457 -COIS- Competing interests: None for DGH. JWE has received research funding from Bayer - and Sanofi‐Aventis. -EDAT- 2006/10/13 09:00 -MHDA- 2007/04/18 09:00 -PMCR- 2010/03/01 -CRDT- 2006/10/13 09:00 -PHST- 2006/10/13 09:00 [pubmed] -PHST- 2007/04/18 09:00 [medline] -PHST- 2006/10/13 09:00 [entrez] -PHST- 2010/03/01 00:00 [pmc-release] -AID - hrt.2006.102350 [pii] -AID - ht102350 [pii] -AID - 10.1136/hrt.2006.102350 [doi] -PST - ppublish -SO - Heart. 2007 Mar;93(3):303-8. doi: 10.1136/hrt.2006.102350. Epub 2006 Oct 11. - -PMID- 20453442 -OWN - NLM -STAT- MEDLINE -DCOM- 20100923 -LR - 20191111 -IS - 1349-7413 (Electronic) -IS - 0911-4300 (Linking) -VI - 33 -IP - 2 -DP - 2010 -TI - Identification of susceptibility genes for Kawasaki disease. -PG - 73-80 -AB - Kawasaki disease is an acute febrile illness of infants and children with unknown - etiology. Coronary artery lesions occurring in 20-25% of untreated patients of KD - has made KD a leading cause of acquired heart diseases of childhood in developed - countries. High prevalence in East Asian countries is one of the epidemiological - features of KD and has suggested genetic factors underlying the disease - pathogenesis. We tried to identify genetic variants relevant to KD susceptibility - by sibpair linkage study and linkage diseuilibrium mapping with SNPs and found - that inositol 1,4,5-trisphosphate 3-kianse C gene is a susceptibility gene for - KD. We also found the negative regulatory role of ITPKC in TCR signaling and the - mechanism by which the responsible SNP in intron 1 of the gene affects - transcripts level of ITPKC. Our findings highlighted the importance of - Ca(2+)/NFAT pathway in the pathogenesis of KD and shed light on the possibility - of immuno-suppressants targeting the pathway as a therapeutic strategy for KD. -FAU - Onouchi, Yoshihiro -AU - Onouchi Y -AD - Laboratory for Cardiovascular disease, Center for Genomic Medicine, RIKEN. -LA - eng -PT - Journal Article -PT - Review -PL - Japan -TA - Nihon Rinsho Meneki Gakkai Kaishi -JT - Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology -JID - 9505992 -RN - 0 (HLA Antigens) -RN - 0 (NFATC Transcription Factors) -RN - 0 (Receptors, Antigen, T-Cell) -RN - EC 2.7.1.- (Phosphotransferases (Alcohol Group Acceptor)) -RN - EC 2.7.1.127 (Inositol 1,4,5-trisphosphate 3-kinase) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Calcium/physiology -MH - Child -MH - Child, Preschool -MH - Chromosome Mapping -MH - Genetic Predisposition to Disease/*genetics -MH - HLA Antigens/genetics -MH - Humans -MH - Infant -MH - Linkage Disequilibrium -MH - Mucocutaneous Lymph Node Syndrome/*genetics -MH - NFATC Transcription Factors/physiology -MH - Phosphotransferases (Alcohol Group Acceptor)/*genetics/physiology -MH - Polymorphism, Single Nucleotide/genetics -MH - Receptors, Antigen, T-Cell/genetics/physiology -MH - Signal Transduction/genetics/physiology -MH - Transcription, Genetic/genetics -RF - 25 -EDAT- 2010/05/11 06:00 -MHDA- 2010/09/24 06:00 -CRDT- 2010/05/11 06:00 -PHST- 2010/05/11 06:00 [entrez] -PHST- 2010/05/11 06:00 [pubmed] -PHST- 2010/09/24 06:00 [medline] -AID - JST.JSTAGE/jsci/33.73 [pii] -AID - 10.2177/jsci.33.73 [doi] -PST - ppublish -SO - Nihon Rinsho Meneki Gakkai Kaishi. 2010;33(2):73-80. doi: 10.2177/jsci.33.73. - -PMID- 22727981 -OWN - NLM -STAT- MEDLINE -DCOM- 20130301 -LR - 20161209 -IS - 2213-0276 (Electronic) -IS - 0755-4982 (Linking) -VI - 42 -IP - 1 -DP - 2013 Jan -TI - [Cardiotoxicity of chemotherapies]. -PG - 26-39 -LID - S0755-4982(12)00282-5 [pii] -LID - 10.1016/j.lpm.2012.04.014 [doi] -AB - The spectrum of chemotherapy's cardiac side effect of chemotherapy has expanded - with the new combinations of cytotoxic and targeted therapies over the past 10 - years. Moreover, cancer therapy administrated to "new" populations, especially - elderly patients or patients with cardiovascular disease and/or coronary artery - disease history, has increased considerably. According to the American College of - Cardiology and American Heart Association (ACC/AHA), patients receiving - chemotherapy can be considered in the A group of heart failure. Many - cardiovascular adverse effects appear with cancer therapy and suspend treatment - purchase, or leading to an alteration of quality of life, and increasing - mortality risks. The most clinically evident cardiotoxicity and best known is the - anthracyclines adverse effect. Other cytotoxic are associated with a significant - risk of cardiovascular complications include alkylating agents such as - 5-fluorouracil and paclitaxel. Cardiovascular adverse effects are associated with - the use of targeted therapies such as tyrosine kinase inhibitors: trastuzumab, - bevacizumab. At the same time, drugs used to hematological malignancies, as acid - all-trans-retinoic acid and arsenic trioxide are cardiotoxics. The most serious - cardiac complications of cancer therapies is heart congestive failure, mainly due - to the use of anthracyclines, cyclophosphamide and trastuzumab, usually at high - doses. Myocardial ischemia is mainly caused by interferon and antimetabolites. - Other side effects may occur such as hypotension, hypertension, arrhythmias and - conduction disturbances, pericarditis, and thromboembolic complications. -CI - Copyright © 2012. Published by Elsevier Masson SAS. -FAU - Castel, Marion -AU - Castel M -AD - Institut des maladies métaboliques et cardiovasculaires de Rangueil, IFR31, UPS, - université de Toulouse, Inserm, U1048, 31432 Toulouse, France. -FAU - Despas, Fabien -AU - Despas F -FAU - Modesto, Anouchka -AU - Modesto A -FAU - Gales, Céline -AU - Gales C -FAU - Honton, Benjamin -AU - Honton B -FAU - Galinier, Michel -AU - Galinier M -FAU - Senard, Jean-Michel -AU - Senard JM -FAU - Pathak, Atul -AU - Pathak A -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Effets indésirables cardiaques des chimiothérapies. -DEP - 20120621 -PL - France -TA - Presse Med -JT - Presse medicale (Paris, France : 1983) -JID - 8302490 -RN - 0 (Antibodies, Monoclonal, Humanized) -RN - 0 (Antineoplastic Agents, Alkylating) -RN - 0 (Protein Kinase Inhibitors) -RN - 0 (Taxoids) -SB - IM -MH - Antibodies, Monoclonal, Humanized/adverse effects -MH - Antineoplastic Agents, Alkylating/adverse effects -MH - Antineoplastic Combined Chemotherapy Protocols/*adverse effects -MH - Drug-Related Side Effects and Adverse Reactions/epidemiology -MH - Heart Diseases/*chemically induced/epidemiology/prevention & control/therapy -MH - Heart Failure/chemically induced/epidemiology/therapy -MH - Humans -MH - Molecular Targeted Therapy/adverse effects/methods -MH - Myocardial Ischemia/chemically induced/epidemiology -MH - Protein Kinase Inhibitors/adverse effects -MH - Taxoids/adverse effects -EDAT- 2012/06/26 06:00 -MHDA- 2013/03/02 06:00 -CRDT- 2012/06/26 06:00 -PHST- 2011/10/25 00:00 [received] -PHST- 2012/04/11 00:00 [revised] -PHST- 2012/04/12 00:00 [accepted] -PHST- 2012/06/26 06:00 [entrez] -PHST- 2012/06/26 06:00 [pubmed] -PHST- 2013/03/02 06:00 [medline] -AID - S0755-4982(12)00282-5 [pii] -AID - 10.1016/j.lpm.2012.04.014 [doi] -PST - ppublish -SO - Presse Med. 2013 Jan;42(1):26-39. doi: 10.1016/j.lpm.2012.04.014. Epub 2012 Jun - 21. - -PMID- 17342004 -OWN - NLM -STAT- MEDLINE -DCOM- 20070420 -LR - 20191110 -IS - 0889-7204 (Print) -IS - 0889-7204 (Linking) -VI - 22 -IP - 1 -DP - 2007 Winter -TI - Current endovascular treatment of peripheral arterial disease. -PG - 31-7 -AB - Atherosclerotic peripheral arterial disease is a common medical problem worldwide - and portends a poor prognosis because of increased cardiovascular morbidity and - mortality. Regular exercise, weight loss, and aggressive risk factor - modification, including treatment of dyslipidemia and complete cessation of - smoking, is extremely important in this high-risk cohort. Vascular surgery in - these patients, who often have concomitant coronary or cerebrovascular - atherosclerosis, is associated with significant risk. Steady improvements in - endovascular revascularization techniques have made this a safe and effective - alternate revascularization modality. Percutaneous peripheral vascular - interventions have increased dramatically in recent years, from 90,000 in 1994 to - more than 200,000 in 1997, and endovascular techniques may soon replace up to 50% - of traditional vascular operations. In this article, the authors review the - current state of interventional treatment for peripheral arterial disease. -FAU - Mardikar, H M -AU - Mardikar HM -AD - Spandan Heart Institute and Research Center, Nagpur, India. -FAU - Mukherjee, Debabrata -AU - Mukherjee D -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Prog Cardiovasc Nurs -JT - Progress in cardiovascular nursing -JID - 8704064 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Acute Disease -MH - Angioplasty/*methods/nursing/statistics & numerical data -MH - Aortic Diseases/diagnosis/surgery -MH - Combined Modality Therapy -MH - Disease Progression -MH - Exercise Therapy -MH - Femoral Artery -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Iliac Artery -MH - Leg/*blood supply -MH - Nurse's Role -MH - Patient Selection -MH - Perioperative Care/methods/nursing -MH - Peripheral Vascular Diseases/diagnosis/epidemiology/*therapy -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Popliteal Artery -MH - Prognosis -MH - Risk Factors -MH - Risk Reduction Behavior -MH - Safety -MH - Stents -MH - Treatment Outcome -RF - 42 -EDAT- 2007/03/08 09:00 -MHDA- 2007/04/21 09:00 -CRDT- 2007/03/08 09:00 -PHST- 2007/03/08 09:00 [pubmed] -PHST- 2007/04/21 09:00 [medline] -PHST- 2007/03/08 09:00 [entrez] -AID - 10.1111/j.0889-7204.2007.05596.x [doi] -PST - ppublish -SO - Prog Cardiovasc Nurs. 2007 Winter;22(1):31-7. doi: - 10.1111/j.0889-7204.2007.05596.x. - -PMID- 16171772 -OWN - NLM -STAT- MEDLINE -DCOM- 20060314 -LR - 20061115 -IS - 0003-9861 (Print) -IS - 0003-9861 (Linking) -VI - 445 -IP - 2 -DP - 2006 Jan 15 -TI - Myeloperoxidase-mediated oxidation of high-density lipoproteins: fingerprints of - newly recognized potential proatherogenic lipoproteins. -PG - 245-55 -AB - Substantial evidence supports the notion that oxidative processes participate in - the pathogenesis of atherosclerotic heart disease. Major evidence for - myeloperoxidase (MPO) as enzymatic catalyst for oxidative modification of - lipoproteins in the artery wall has been suggested in numerous studies performed - with low-density lipoprotein. In contrast to low-density lipoprotein, plasma - levels of high-density lipoprotein (HDL)-cholesterol and apoAI, the major - apolipoprotein of HDL, inversely correlate with the risk of developing coronary - artery disease. These antiatherosclerotic effects are attributed mainly to HDL's - capacity to transport excess cholesterol from arterial wall cells to the liver - during 'reverse cholesterol transport'. There is now strong evidence that HDL is - a selective in vivo target for MPO-catalyzed oxidation impairing the - cardioprotective and antiinflammatory capacity of this antiatherogenic - lipoprotein. MPO is enzymatically active in human lesion material and was found - to be associated with HDL extracted from human atheroma. MPO-catalyzed oxidation - products are highly enriched in circulating HDL from individuals with - cardiovascular disease where MPO concentrations are also increased. The oxidative - potential of MPO involves an array of intermediate-generated reactive oxygen and - reactive nitrogen species and the ability of MPO to generate chlorinating - oxidants-in particular hypochlorous acid/hypochlorite-under physiological - conditions is a unique and defining activity for this enzyme. All these - MPO-generated reactive products may affect structure and function of HDL as well - as the activity of HDL-associated enzymes involved in conversion and remodeling - of the lipoprotein particle, and represent clinically useful markers for - atherosclerosis. -FAU - Malle, Ernst -AU - Malle E -AD - Institute of Molecular Biology and Biochemistry, Center of Molecular Medicine, - Medical University Graz, A-8010 Graz, Austria. ernst.malle@meduni-graz.at -FAU - Marsche, Gunther -AU - Marsche G -FAU - Panzenboeck, Ute -AU - Panzenboeck U -FAU - Sattler, Wolfgang -AU - Sattler W -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20050831 -PL - United States -TA - Arch Biochem Biophys -JT - Archives of biochemistry and biophysics -JID - 0372430 -RN - 0 (Lipoproteins, HDL) -RN - EC 1.11.1.7 (Peroxidase) -SB - IM -MH - Animals -MH - Atherosclerosis/*enzymology -MH - Humans -MH - Lipoproteins, HDL/*chemistry/*metabolism -MH - Oxidation-Reduction -MH - Peptide Mapping -MH - Peroxidase/*chemistry/*metabolism -MH - Structure-Activity Relationship -RF - 127 -EDAT- 2005/09/21 09:00 -MHDA- 2006/03/15 09:00 -CRDT- 2005/09/21 09:00 -PHST- 2005/06/07 00:00 [received] -PHST- 2005/08/03 00:00 [revised] -PHST- 2005/08/10 00:00 [accepted] -PHST- 2005/09/21 09:00 [pubmed] -PHST- 2006/03/15 09:00 [medline] -PHST- 2005/09/21 09:00 [entrez] -AID - S0003-9861(05)00349-8 [pii] -AID - 10.1016/j.abb.2005.08.008 [doi] -PST - ppublish -SO - Arch Biochem Biophys. 2006 Jan 15;445(2):245-55. doi: 10.1016/j.abb.2005.08.008. - Epub 2005 Aug 31. - -PMID- 24270960 -OWN - NLM -STAT- MEDLINE -DCOM- 20140930 -LR - 20220629 -IS - 1980-5322 (Electronic) -IS - 1807-5932 (Print) -IS - 1807-5932 (Linking) -VI - 68 -IP - 11 -DP - 2013 Nov -TI - Sexual dysfunction and cardiovascular diseases: a systematic review of - prevalence. -PG - 1462-8 -LID - 10.6061/clinics/2013(11)13 [doi] -AB - The aim of this study was to conduct a systematic review of the literature - regarding the prevalence of sexual dysfunction in patients with cardiovascular - diseases. An article search of the ISI Web of Science and PubMed databases using - the search terms "sexual dysfunction", "cardiovascular diseases", "coronary - artery disease", "myocardial infarct" and "prevalence" was performed. In total, - 893 references were found. Non-English-language and repeated references were - excluded. After an abstract analysis, 91 references were included for full-text - reading, and 24 articles that evaluated sexual function using validated - instruments were selected for this review. This research was conducted in October - 2012, and no time restrictions were placed on any of the database searches. - Reviews and theoretical articles were excluded; only clinical trials and - epidemiological studies were selected for this review. The studies were mostly - cross-sectional, observational and case-control in nature; other studies used - prospective cohort or randomized clinical designs. In women, all domains of - sexual function (desire, arousal, vaginal lubrication, orgasm, sexual - dissatisfaction and pain) were affected. The domains prevalent in men included - erectile dysfunction and premature ejaculation and orgasm. Sexual dysfunction was - related to the severity of cardiovascular disease. When they resumed sexual - activity, patients with heart disease reported significant difficulty, including - a lack of interest in sex, sexual dissatisfaction and a decrease in the frequency - of sexual activity. -FAU - Nascimento, Elisabete Rodrigues -AU - Nascimento ER -AD - Laboratory of Panic and Respiration, Institute of Psychiatry, Universidade - Federal do Rio de Janeiro, Rio de JaneiroRJ, Brazil. -FAU - Maia, Ana Claudia Ornelas -AU - Maia AC -FAU - Pereira, Valeska -AU - Pereira V -FAU - Soares-Filho, Gastão -AU - Soares-Filho G -FAU - Nardi, Antonio Egidio -AU - Nardi AE -FAU - Silva, Adriana Cardoso -AU - Silva AC -LA - eng -PT - Journal Article -PT - Review -PT - Systematic Review -PL - United States -TA - Clinics (Sao Paulo) -JT - Clinics (Sao Paulo, Brazil) -JID - 101244734 -SB - IM -MH - Cardiovascular Diseases/complications/*epidemiology -MH - Epidemiologic Studies -MH - Female -MH - Humans -MH - Male -MH - Prevalence -MH - Randomized Controlled Trials as Topic -MH - Risk Factors -MH - Severity of Illness Index -MH - Sex Factors -MH - Sexual Dysfunction, Physiological/*epidemiology/etiology -PMC - PMC3812559 -COIS- No potential conflict of interest was reported. -EDAT- 2013/11/26 06:00 -MHDA- 2014/10/01 06:00 -PMCR- 2013/11/01 -CRDT- 2013/11/26 06:00 -PHST- 2013/03/30 00:00 [received] -PHST- 2013/06/06 00:00 [accepted] -PHST- 2013/11/26 06:00 [entrez] -PHST- 2013/11/26 06:00 [pubmed] -PHST- 2014/10/01 06:00 [medline] -PHST- 2013/11/01 00:00 [pmc-release] -AID - S1807-5932(22)02059-2 [pii] -AID - cln_68p1462 [pii] -AID - 10.6061/clinics/2013(11)13 [doi] -PST - ppublish -SO - Clinics (Sao Paulo). 2013 Nov;68(11):1462-8. doi: 10.6061/clinics/2013(11)13. - -PMID- 20685686 -OWN - NLM -STAT- MEDLINE -DCOM- 20110621 -LR - 20220311 -IS - 1879-0844 (Electronic) -IS - 1388-9842 (Linking) -VI - 12 -IP - 10 -DP - 2010 Oct -TI - Length of delay in seeking medical care by patients with heart failure symptoms - and the role of symptom-related factors: a narrative review. -PG - 1122-9 -LID - 10.1093/eurjhf/hfq122 [doi] -AB - AIMS: The delay in seeking timely medical care by patients with acute coronary - syndrome and stroke is well established. Less is known about the delay in - patients with heart failure (HF). Reducing the delay in seeking care and the - early initiation of treatment is associated with improved outcomes in patients - with HF. The purpose of this narrative review was to describe the length of the - delay in seeking care for HF symptoms and identify symptom-related factors that - contribute to the delay in seeking medical care. METHODS AND RESULTS: A - literature search was conducted to identify English language studies that (i) - describe the length of care-seeking delay for HF symptoms and/or (ii) identify - symptom-related factors that contribute to delay in seeking medical care. The - results of this review demonstrate that upon hospital admission patients report - wide variations in median symptom time course from 2 h to 7 days from the onset - of symptoms to hospital admission. The ability of patients to recognize, - interpret, and appraise HF symptoms has been demonstrated to be limited. Symptom - characteristics such as dyspnoea, oedema, orthopnoea, higher somatic awareness, - higher symptom distress, nocturnal symptom onset, and the pattern of symptom - onset were related to longer delay in care-seeking for HF symptoms. Furthermore, - cognitive responses to HF may also play an important role in symptom appraisal. - CONCLUSION: Delays in seeking care for HF symptoms have been shown to range from - hours to days from symptom onset to hospital admission. Healthcare professionals - should therefore be more vigilant in identifying high-risk individuals and - educating them about the warning signs of HF. Moreover, access to outpatient - chronic disease management programmes may have the potential to reduce these - delays. -FAU - Gravely-Witte, Shannon -AU - Gravely-Witte S -AD - York University, Faculty of Health, Norman Bethune College 368, 4700 Keele - Street, Toronto, Ontario, Canada M3J 1P3. -FAU - Jurgens, Corrine Y -AU - Jurgens CY -FAU - Tamim, Hala -AU - Tamim H -FAU - Grace, Sherry L -AU - Grace SL -LA - eng -PT - Journal Article -PT - Review -DEP - 20100803 -PL - England -TA - Eur J Heart Fail -JT - European journal of heart failure -JID - 100887595 -SB - IM -MH - Aged -MH - Confidence Intervals -MH - Female -MH - *Health Knowledge, Attitudes, Practice -MH - Heart Failure/complications/physiopathology/*psychology/*therapy -MH - Hospitalization -MH - Humans -MH - Male -MH - Middle Aged -MH - Odds Ratio -MH - *Patient Acceptance of Health Care -MH - Patient Education as Topic -MH - Risk Factors -MH - Time Factors -EDAT- 2010/08/06 06:00 -MHDA- 2011/06/22 06:00 -CRDT- 2010/08/06 06:00 -PHST- 2010/08/06 06:00 [entrez] -PHST- 2010/08/06 06:00 [pubmed] -PHST- 2011/06/22 06:00 [medline] -AID - hfq122 [pii] -AID - 10.1093/eurjhf/hfq122 [doi] -PST - ppublish -SO - Eur J Heart Fail. 2010 Oct;12(10):1122-9. doi: 10.1093/eurjhf/hfq122. Epub 2010 - Aug 3. - -PMID- 21135807 -OWN - NLM -STAT- MEDLINE -DCOM- 20110419 -LR - 20101207 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 58 -IP - 6 -DP - 2010 Dec -TI - Management of ventricular arrhythmias. -PG - 657-76 -AB - Underlying causes of ventricular tachycardia (VT) or complex ventricular - arrhythmias (VA) should be treated if possible. Anti-arrhythmic drugs should not - be used to treat asymptomatic patients with complex VA and no heart disease. Beta - blockers are the only antiarrhythmic drugs that have been documented to reduce - mortality in patients with VT or complex VA. Radiofrequency catheter ablation of - VT has been beneficial in treating selected patients with arrhythmogenic foci of - monomorphic VT. The automatic implantable cardioverter-defibrillator (AICD) is - the most effective treatment for patients with life-threatening VT or ventricular - fibrillation. The American College of Cardiology/American Heart Association class - I indications for an AICD are discussed. Other indications for an AICD are - discussed. Patients with AICDs should be treated with biventricular pacing, not - with dual-chamber rate-responsive pacing at a rate of 70/minute. Patients with - AICDs should be treated with beta blockers, statins, and angiotensin-converting - enzyme inhibitors or angiotensin blockers. -FAU - Aronow, W S -AU - Aronow WS -AD - Cardiology Division, Department of Medicine, New York Medical College, Valhalla, - New York, NY 10595, USA. wsaronow@aol.com -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Calcium Channel Blockers) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Anti-Arrhythmia Agents/therapeutic use -MH - Calcium Channel Blockers/therapeutic use -MH - Cardiac Resynchronization Therapy/methods -MH - Catheter Ablation -MH - Coronary Artery Bypass -MH - Death, Sudden, Cardiac/prevention & control -MH - Defibrillators, Implantable -MH - Drug Therapy, Combination -MH - Heart Conduction System/physiopathology -MH - Humans -MH - Prevalence -MH - Prognosis -MH - Severity of Illness Index -MH - Survival Analysis -MH - Tachycardia, Ventricular/diagnosis/epidemiology/physiopathology/*therapy -MH - Treatment Outcome -MH - Ventricular Fibrillation/therapy -EDAT- 2010/12/08 06:00 -MHDA- 2011/04/20 06:00 -CRDT- 2010/12/08 06:00 -PHST- 2010/12/08 06:00 [entrez] -PHST- 2010/12/08 06:00 [pubmed] -PHST- 2011/04/20 06:00 [medline] -AID - R05102995 [pii] -PST - ppublish -SO - Minerva Cardioangiol. 2010 Dec;58(6):657-76. - -PMID- 19075610 -OWN - NLM -STAT- MEDLINE -DCOM- 20090310 -LR - 20191111 -IS - 1570-1638 (Print) -IS - 1570-1638 (Linking) -VI - 5 -IP - 4 -DP - 2008 Dec -TI - The effect of acute hypoxia on excitability in the heart and the L-type calcium - channel as a therapeutic target. -PG - 302-11 -AB - Acute hypoxia is induced during coronary occlusion or when oxygen supply does not - meet demand and can trigger cardiac arrhythmia. Cardiac ion channels shape the - action potential and excitability of the heart. Acute hypoxia regulates the - function of cardiac ion channels including the L-type Ca(2+) channel that is the - main route for Ca(2+)influx into cardiac myocytes and shapes the plateau phase of - the action potential. This article will review the evidence for alteration of ion - channel function during hypoxia as a result of modification of thiol groups by - reactive oxygen species. The effect of acute hypoxia on cardiac excitability will - be examined and how this can lead to life threatening arrhythmias with particular - reference to the L-type Ca(2+) channel. Recent evidence indicates the L-type - Ca(2+) channel is a suitable target for the development of drugs that can modify - channel function during hypoxia or oxidative stress to prevent induction of - arrhythmia or development of pathology. -FAU - Macdonald, William A -AU - Macdonald WA -AD - School of Biomedical, Biomolecular and Chemical Sciences, University of Western - Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia. -FAU - Hool, Livia C -AU - Hool LC -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Drug Discov Technol -JT - Current drug discovery technologies -JID - 101157212 -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Calcium Channels, L-Type) -RN - 0 (Ion Channels) -RN - 0 (Reactive Oxygen Species) -SB - IM -MH - Action Potentials/physiology -MH - Acute Disease -MH - Animals -MH - Anti-Arrhythmia Agents/*therapeutic use -MH - Arrhythmias, Cardiac/drug therapy/*prevention & control -MH - Calcium Channel Blockers/pharmacology -MH - Calcium Channels, L-Type/metabolism/*physiology -MH - Heart/physiology -MH - Hypoxia/metabolism/*physiopathology -MH - Ion Channels/metabolism -MH - Oxidative Stress -MH - Reactive Oxygen Species/poisoning -RF - 112 -EDAT- 2008/12/17 09:00 -MHDA- 2009/03/11 09:00 -CRDT- 2008/12/17 09:00 -PHST- 2008/12/17 09:00 [entrez] -PHST- 2008/12/17 09:00 [pubmed] -PHST- 2009/03/11 09:00 [medline] -AID - 10.2174/157016308786733546 [doi] -PST - ppublish -SO - Curr Drug Discov Technol. 2008 Dec;5(4):302-11. doi: 10.2174/157016308786733546. - -PMID- 21792599 -OWN - NLM -STAT- MEDLINE -DCOM- 20120313 -LR - 20211020 -IS - 1432-1289 (Electronic) -IS - 0020-9554 (Linking) -VI - 52 -IP - 10 -DP - 2011 Oct -TI - [New tyrosine kinase and EGFR inhibitors in cancer therapy. Cardiac and skin - toxicity as relevant side effects. Part A: heart]. -PG - 1245-55 -LID - 10.1007/s00108-011-2895-3 [doi] -AB - Cardiotoxicity is a serious side effect of targeted molecular therapies in cancer - treatment. Monoclonal antibodies and tyrosine kinase inhibitors are known to be - potent therapies in various neoplastic diseases due to inhibition of specific - signal transduction pathways. Although targeted therapies are considered to be - less toxic and better tolerated than common chemotherapies certain cardiac side - effects have been observed. Cardiac toxicity may range from asymptomatic - reduction of left ventricular function to life-threatening events like heart - failure and acute coronary syndrome. Further side effects are arterial - hypertension, thrombosis and arrhythmias. Cardiovascular side effects are common - for anti-HER2 therapy in combination with anthracyclines and for inhibitors of - angiogenesis. In these patients careful cardiac monitoring is warranted. Because - of missing randomized long-term follow-ups, information about cardiac side - effects is limited in newly developed targeted molecular therapies. In case of - cardiac side effects or preexisting cardiac disease before therapy initiation, - assessments by a cardiologist throughout the course of treatment are important. - For patients with severe cardiac side effects, discontinuation of treatment is - warranted; in case of asymptomatic cardiac side effects symptom-specific therapy - should be performed. -FAU - Rottlaender, D -AU - Rottlaender D -AD - Klinik III für Innere Medizin, Universität zu Köln, Kerpener-Straße 62, 50937, - Köln, Deutschland. -FAU - Reda, S -AU - Reda S -FAU - Motloch, L J -AU - Motloch LJ -FAU - Hoppe, U C -AU - Hoppe UC -LA - ger -PT - Journal Article -PT - Review -TT - Neue Tyrosinkinase- und EGFR-Inhibitoren in der Tumortherapie. Herz und Haut als - wichtige Schädigungsorgane. Teil A: Herz. -PL - Germany -TA - Internist (Berl) -JT - Der Internist -JID - 0264620 -RN - 0 (Antibodies, Monoclonal) -RN - 0 (Antineoplastic Agents) -RN - EC 2.7.10.1 (EGFR protein, human) -RN - EC 2.7.10.1 (ErbB Receptors) -RN - EC 2.7.10.1 (Protein-Tyrosine Kinases) -SB - IM -MH - Antibodies, Monoclonal/therapeutic use/*toxicity -MH - Antineoplastic Agents/therapeutic use/*toxicity -MH - Antineoplastic Combined Chemotherapy Protocols/therapeutic use/toxicity -MH - Cooperative Behavior -MH - ErbB Receptors/*antagonists & inhibitors -MH - Heart Diseases/*chemically induced -MH - Humans -MH - Interdisciplinary Communication -MH - Neoplasms/*drug therapy -MH - Protein-Tyrosine Kinases/*antagonists & inhibitors -EDAT- 2011/07/28 06:00 -MHDA- 2012/03/14 06:00 -CRDT- 2011/07/28 06:00 -PHST- 2011/07/28 06:00 [entrez] -PHST- 2011/07/28 06:00 [pubmed] -PHST- 2012/03/14 06:00 [medline] -AID - 10.1007/s00108-011-2895-3 [doi] -PST - ppublish -SO - Internist (Berl). 2011 Oct;52(10):1245-55. doi: 10.1007/s00108-011-2895-3. - -PMID- 24332285 -OWN - NLM -STAT- MEDLINE -DCOM- 20140811 -LR - 20220318 -IS - 1876-7591 (Electronic) -IS - 1936-878X (Print) -IS - 1876-7591 (Linking) -VI - 6 -IP - 12 -DP - 2013 Dec -TI - The advancing clinical impact of molecular imaging in CVD. -PG - 1327-41 -LID - S1936-878X(13)00702-X [pii] -LID - 10.1016/j.jcmg.2013.09.014 [doi] -AB - Molecular imaging seeks to unravel critical molecular and cellular events in - living subjects by providing complementary biological information to current - structural clinical imaging modalities. In recent years, molecular imaging - efforts have marched forward into the clinical cardiovascular arena, and are now - actively illuminating new biology in a broad range of conditions, including - atherosclerosis, myocardial infarction, thrombosis, vasculitis, aneurysm, - cardiomyopathy, and valvular disease. Development of novel molecular imaging - reporters is occurring for many clinical cardiovascular imaging modalities - (positron emission tomography, single-photon emission computed tomography, - magnetic resonance imaging), as well as in translational platforms such as - intravascular fluorescence imaging. The ability to image, track, and quantify - molecular biomarkers in organs not routinely amenable to biopsy (e.g., the heart - and vasculature) open new clinical opportunities to tailor therapeutics based on - a cardiovascular disease molecular profile. In addition, molecular imaging is - playing an increasing role in atherosclerosis drug development in phase II - clinical trials. Here, we present state-of-the-art clinical cardiovascular - molecular imaging strategies, and explore promising translational approaches - positioned for clinical testing in the near term. -CI - Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Osborn, Eric A -AU - Osborn EA -AD - Cardiology Division, Beth Israel Deaconess Medical Center, Harvard Medical - School, Boston, Massachusetts; Cardiovascular Research Center, Cardiology - Division, Massachusetts General Hospital, Harvard Medical School, Boston, - Massachusetts. -FAU - Jaffer, Farouc A -AU - Jaffer FA -AD - Cardiovascular Research Center, Cardiology Division, Massachusetts General - Hospital, Harvard Medical School, Boston, Massachusetts; Center for Molecular - Imaging Research and Wellman Center for Photomedicine, Massachusetts General - Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: - fjaffer@mgh.harvard.edu. -LA - eng -GR - R01 HL108229/HL/NHLBI NIH HHS/United States -GR - T32 HL007374/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - JACC Cardiovasc Imaging -JT - JACC. Cardiovascular imaging -JID - 101467978 -RN - 0 (Biomarkers) -SB - IM -MH - Biomarkers/metabolism -MH - Cardiovascular Diseases/*diagnosis/metabolism/therapy -MH - Humans -MH - *Molecular Imaging/methods -MH - Patient Selection -MH - Predictive Value of Tests -MH - Prognosis -PMC - PMC3876961 -MID - NIHMS537888 -OTO - NOTNLM -OT - (158)Gd-ESMA -OT - (18)F-fluorodeoxyglucose -OT - (18)F-sodium fluoride -OT - AS -OT - AT1R -OT - CAC -OT - CEA -OT - CMR -OT - CT -OT - DVT -OT - FDA -OT - FDG -OT - Food and Drug Administration -OT - ICG -OT - LDL -OT - LV -OT - MI -OT - MMP -OT - MRI -OT - NIRF -OT - NaF -OT - OFDI -OT - OTW -OT - PC -OT - PET -OT - RAAS -OT - SUV -OT - TBR -OT - USPIO -OT - aneurysm -OT - angiotensin II type 1 receptor -OT - aortic stenosis -OT - atherosclerosis -OT - cardiac magnetic resonance -OT - carotid endarterectomy -OT - computed tomography -OT - coronary artery calcium -OT - deep vein thrombosis -OT - gadolinium-labeled elastin-specific magnetic resonance contrast agent -OT - heart failure -OT - high-sensitivity C-reactive protein -OT - hsCRP -OT - indocyanine green -OT - left ventricle/ventricular -OT - low-density lipoprotein -OT - magnetic resonance imaging -OT - matrix metalloproteinase -OT - molecular imaging -OT - myocardial infarction -OT - near-infrared fluorescence -OT - optical frequency domain imaging -OT - over-the-wire -OT - perfusion catheter -OT - positron emission tomography -OT - renin-angiotensin-aldosterone system -OT - standardized uptake value -OT - target-to-background ratio -OT - thrombosis -OT - ultrasmall superparamagnetic particles of iron oxide -OT - valvular disease -OT - vascular injury -EDAT- 2013/12/18 06:00 -MHDA- 2014/08/12 06:00 -PMCR- 2014/12/01 -CRDT- 2013/12/17 06:00 -PHST- 2013/09/23 00:00 [received] -PHST- 2013/09/25 00:00 [accepted] -PHST- 2013/12/17 06:00 [entrez] -PHST- 2013/12/18 06:00 [pubmed] -PHST- 2014/08/12 06:00 [medline] -PHST- 2014/12/01 00:00 [pmc-release] -AID - S1936-878X(13)00702-X [pii] -AID - 10.1016/j.jcmg.2013.09.014 [doi] -PST - ppublish -SO - JACC Cardiovasc Imaging. 2013 Dec;6(12):1327-41. doi: 10.1016/j.jcmg.2013.09.014. - -PMID- 22824295 -OWN - NLM -STAT- MEDLINE -DCOM- 20130408 -LR - 20120827 -IS - 1876-4738 (Electronic) -IS - 0914-5087 (Linking) -VI - 60 -IP - 2 -DP - 2012 Aug -TI - Sleep apnea and heart failure. -PG - 78-85 -LID - 10.1016/j.jjcc.2012.05.013 [doi] -AB - Sleep apnea is frequently observed in patients with heart failure (HF). In - general, sleep apnea consists of two types: obstructive and central sleep apnea - (OSA and CSA, respectively). OSA results from upper airway collapse, whereas CSA - arises from reductions in central respiratory drive. In patients with OSA, blood - pressure is frequently elevated as a result of sympathetic nervous system - overactivation. The generation of exaggerated negative intrathoracic pressure - during obstructive apneas further increases left ventricular (LV) afterload, - reduces cardiac output, and may promote the progression of HF. Intermittent - hypoxia and post-apneic reoxygenation cause vascular endothelial damage and - possibly atherosclerosis and consequently coronary artery disease and ischemic - cardiomyopathy. CSA is also characterized by apnea, hypoxia, and increased - sympathetic nervous activity and, when present in HF, is associated with - increased risk of death. In patients with HF, abolition of coexisting OSA by - continuous positive airway pressure (CPAP) improves LV function and may - contribute to the improvement of long-term outcomes. Although treatment options - of CSA vary compared with OSA treatment, CPAP and other types of positive airway - ventilation improve LV function and may be a promising adjunctive therapy for HF - patients with CSA. Since HF remains one of the major causes of mortality in the - industrialized countries, the significance of identifying and managing sleep - apnea should be more emphasized to prevent the development or progression of HF. -CI - Copyright © 2012 Japanese College of Cardiology. Published by Elsevier Ltd. All - rights reserved. -FAU - Kasai, Takatoshi -AU - Kasai T -AD - Cardio-Respiratory Sleep Medicine, Department of Cardiology, Juntendo University, - School of Medicine, Tokyo, Japan. kasai-t@mx6.nisiq.net -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120721 -PL - Netherlands -TA - J Cardiol -JT - Journal of cardiology -JID - 8804703 -SB - IM -MH - Heart Failure/*complications -MH - Humans -MH - Risk Factors -MH - Sleep Apnea Syndromes/*complications/physiopathology/therapy -MH - Sleep Apnea, Central/complications -MH - Sleep Apnea, Obstructive/physiopathology -EDAT- 2012/07/25 06:00 -MHDA- 2013/04/09 06:00 -CRDT- 2012/07/25 06:00 -PHST- 2012/05/17 00:00 [received] -PHST- 2012/05/28 00:00 [accepted] -PHST- 2012/07/25 06:00 [entrez] -PHST- 2012/07/25 06:00 [pubmed] -PHST- 2013/04/09 06:00 [medline] -AID - S0914-5087(12)00108-6 [pii] -AID - 10.1016/j.jjcc.2012.05.013 [doi] -PST - ppublish -SO - J Cardiol. 2012 Aug;60(2):78-85. doi: 10.1016/j.jjcc.2012.05.013. Epub 2012 Jul - 21. - -PMID- 16481874 -OWN - NLM -STAT- MEDLINE -DCOM- 20060718 -LR - 20151119 -IS - 1062-4821 (Print) -IS - 1062-4821 (Linking) -VI - 15 -IP - 2 -DP - 2006 Mar -TI - Cardiovascular disease in the dialysis population: prognostic significance of - arterial disorders. -PG - 105-10 -AB - PURPOSE OF REVIEW: Cardiovascular disease is a major factor in the high mortality - of patients with end-stage renal disease, and this population is particularly - appropriate to analyse the impact of cardiovascular risk markers on outcome. - RECENT FINDINGS: Cardiovascular risk markers in end-stage renal disease include - age, left ventricular mass, carotid intima-media thickness, blood pressure and - aortic stiffness (pulse wave velocity). Aortic pulse wave velocity has been shown - to be an independent predictor of cardiovascular mortality in patients with - end-stage renal disease and the general population. Aortic pulse wave velocity - has the highest sensitivity and specificity as a predictor of cardiovascular - death in end-stage renal disease patients. Pulse wave velocity is an integrated - index of vascular function and structure, and is a major determinant of systolic - hypertension, thereby increasing left ventricular afterload, left ventricular - hypertrophy and left ventricular oxygen consumption. Decreased diastolic blood - pressure, another consequence of arterial stiffening, is associated with - decreased coronary perfusion contributing to ischaemic heart disease and - evolution of adaptive into maladaptive left ventricular hypertrophy. SUMMARY: - Aortic stiffness measurements could serve as an important tool in identifying - end-stage renal disease patients at higher risk of cardiovascular disease. The - ability to identify these patients would lead to better risk stratification and - earlier and more cost-effective preventive therapy. -FAU - Guérin, Alain P -AU - Guérin AP -AD - Department of Haemodialysis, F.H. Manhès Hospital, Fleury-Mérogis, France. -FAU - Pannier, Bruno -AU - Pannier B -FAU - Marchais, Sylvain J -AU - Marchais SJ -FAU - London, Gérard M -AU - London GM -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Curr Opin Nephrol Hypertens -JT - Current opinion in nephrology and hypertension -JID - 9303753 -RN - 0 (Biomarkers) -SB - IM -MH - Adult -MH - Age Distribution -MH - Aged -MH - Arteriosclerosis/epidemiology/*etiology -MH - Biomarkers/blood -MH - Calcinosis/epidemiology/*etiology -MH - Cardiovascular Diseases/*epidemiology/*etiology -MH - Disease Progression -MH - Female -MH - Humans -MH - Kidney Failure, Chronic/diagnosis/therapy -MH - Male -MH - Middle Aged -MH - Prevalence -MH - Prognosis -MH - Renal Dialysis/*adverse effects/methods -MH - Risk Assessment -MH - Sex Distribution -MH - Survival Rate -RF - 70 -EDAT- 2006/02/17 09:00 -MHDA- 2006/07/19 09:00 -CRDT- 2006/02/17 09:00 -PHST- 2006/02/17 09:00 [pubmed] -PHST- 2006/07/19 09:00 [medline] -PHST- 2006/02/17 09:00 [entrez] -AID - 00041552-200603000-00003 [pii] -AID - 10.1097/01.mnh.0000203186.11772.21 [doi] -PST - ppublish -SO - Curr Opin Nephrol Hypertens. 2006 Mar;15(2):105-10. doi: - 10.1097/01.mnh.0000203186.11772.21. - -PMID- 19564701 -OWN - NLM -STAT- MEDLINE -DCOM- 20091215 -LR - 20190819 -IS - 1347-4820 (Electronic) -IS - 1346-9843 (Linking) -VI - 73 -IP - 8 -DP - 2009 Aug -TI - Obstructive sleep apnea and cardiovascular disease. -PG - 1363-70 -AB - Over the past few decades, sleep apnea has emerged as an important potential - etiologic factor in a broad range of cardiac and vascular diseases. These disease - conditions include hypertension, coronary artery disease, myocardial infarction, - heart failure, and stroke. Recognition of the role of sleep apnea in clinical - cardiology is also increasing in Japan. Although sleep apnea has been strongly - linked to obesity in Western populations, in Japanese and other Asian populations - there is evidence to indicate that sleep apnea may be prevalent even at lower - levels of obesity. In this review we address the epidemiology of sleep apnea. - Since sleep apnea includes the combined stresses of hypoxemia, apnea, and - disrupted sleep, we also review briefly the potential disease mechanisms that may - be activated as a consequence of sleep apnea. We further examine the role of - sleep apnea in the pathophysiology and management of specific cardiovascular - conditions. Overall, while the evidence of sleep apnea as a causal mechanism in - cardiovascular disease is strong and increasing, definitive evidence of the - etiologic role of sleep apnea has yet to be obtained. The evidence is most clear - in patients with hypertension. Also remaining to be established is whether the - treatment of sleep apnea prevents cardiac and vascular events. With regard to - this question, although the available data strongly suggest that continuous - positive airway pressure treatment is beneficial, randomized control trials are - needed in order to confirm this. -FAU - Kato, Masahiko -AU - Kato M -AD - Department of Cardiovascular Medicine, Tottori University, Yonago, Japan. - mkato@grape.med.tottori-u.ac.jp -FAU - Adachi, Taro -AU - Adachi T -FAU - Koshino, Yuki -AU - Koshino Y -FAU - Somers, Virend K -AU - Somers VK -LA - eng -GR - 1 UL1 RR024150/RR/NCRR NIH HHS/United States -GR - HL65176/HL/NHLBI NIH HHS/United States -GR - HL73211/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090630 -PL - Japan -TA - Circ J -JT - Circulation journal : official journal of the Japanese Circulation Society -JID - 101137683 -SB - IM -MH - Cardiovascular Diseases/*etiology/prevention & control -MH - Continuous Positive Airway Pressure -MH - Humans -MH - Hypertension -MH - Japan/epidemiology -MH - Sleep Apnea, Obstructive/*complications/therapy -RF - 134 -EDAT- 2009/07/01 09:00 -MHDA- 2009/12/16 06:00 -CRDT- 2009/07/01 09:00 -PHST- 2009/07/01 09:00 [entrez] -PHST- 2009/07/01 09:00 [pubmed] -PHST- 2009/12/16 06:00 [medline] -AID - JST.JSTAGE/circj/CJ-09-0364 [pii] -AID - 10.1253/circj.cj-09-0364 [doi] -PST - ppublish -SO - Circ J. 2009 Aug;73(8):1363-70. doi: 10.1253/circj.cj-09-0364. Epub 2009 Jun 30. - -PMID- 19158812 -OWN - NLM -STAT- MEDLINE -DCOM- 20100203 -LR - 20151119 -IS - 1435-232X (Electronic) -IS - 1434-5161 (Linking) -VI - 54 -IP - 2 -DP - 2009 Feb -TI - Susceptibility genes for Kawasaki disease: toward implementation of personalized - medicine. -PG - 67-73 -LID - 10.1038/jhg.2008.9 [doi] -AB - Kawasaki disease (KD) is an acute systemic vasculitis syndrome, which primarily - affects in children under the age of 5 years. In 20-25% of cases, if untreated, - coronary artery lesions develop, making KD the leading cause of acquired heart - disease in children in both Japan and the United States. Since 1970, 19 - nationwide surveys of KD in Japan have been conducted every 2 years and the data - are stored in a database. Even though the etiology of KD remains unknown, despite - enthusiastic research spanning more than 40 years, we have learnt a great deal - about KD from this enormous database. These 19 epidemiologic studies indicate a - strong genetic influence on the disease susceptibility, prompting us and other - researchers to identify the responsible genes for KD by applying either the - candidate gene approach or the genome-wide approach. We have employed a - genome-wide linkage study using affected sibling pair data of KD in Japan and - have identified several susceptibility loci. Further analysis focusing on a - region of chromosome 19, where one of the linked loci was detected, identified a - predisposing gene, which codes inositol 1,4,5-trisphosphate 3-kinase C (ITPKC). - In this review, we summarize the cumulative knowledge regarding KD, and then - outline our hypothesis of the role ITPKC plays in KD susceptibility and our trial - that aims toward the implementation of personalized medicine for KD. -FAU - Hata, Akira -AU - Hata A -AD - Department of Public Health, Graduate School of Medicine, Chiba University, - Chiba, Japan. ahata@faculty.chiba-u.jp -FAU - Onouchi, Yoshihiro -AU - Onouchi Y -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090116 -PL - England -TA - J Hum Genet -JT - Journal of human genetics -JID - 9808008 -RN - EC 2.7.1.- (Phosphotransferases (Alcohol Group Acceptor)) -RN - EC 2.7.1.127 (Inositol 1,4,5-trisphosphate 3-kinase) -SB - IM -MH - *Genetic Predisposition to Disease -MH - Humans -MH - Linkage Disequilibrium/genetics -MH - Mucocutaneous Lymph Node Syndrome/epidemiology/etiology/*genetics/therapy -MH - Phosphotransferases (Alcohol Group Acceptor)/genetics -MH - *Precision Medicine -MH - Signal Transduction -RF - 83 -EDAT- 2009/01/23 09:00 -MHDA- 2010/02/04 06:00 -CRDT- 2009/01/23 09:00 -PHST- 2009/01/23 09:00 [entrez] -PHST- 2009/01/23 09:00 [pubmed] -PHST- 2010/02/04 06:00 [medline] -AID - jhg20089 [pii] -AID - 10.1038/jhg.2008.9 [doi] -PST - ppublish -SO - J Hum Genet. 2009 Feb;54(2):67-73. doi: 10.1038/jhg.2008.9. Epub 2009 Jan 16. - -PMID- 22203539 -OWN - NLM -STAT- MEDLINE -DCOM- 20111229 -LR - 20250626 -IS - 1538-3598 (Electronic) -IS - 0098-7484 (Linking) -VI - 306 -IP - 24 -DP - 2011 Dec 28 -TI - CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular - events: a systematic review and meta-analysis. -PG - 2704-14 -LID - 10.1001/jama.2011.1880 [doi] -AB - CONTEXT: The US Food and Drug Administration recently recommended that CYP2C19 - genotyping be considered prior to prescribing clopidogrel, but the American Heart - Association and American College of Cardiologists have argued evidence is - insufficient to support CYP2C19 genotype testing. OBJECTIVE: To appraise evidence - on the association of CYP2C19 genotype and clopidogrel response through - systematic review and meta-analysis. DATA SOURCES: PubMed and EMBASE from their - inception to October 2011. STUDY SELECTION: Studies that reported clopidogrel - metabolism, platelet reactivity or clinically relevant outcomes (cardiovascular - disease [CVD] events and bleeding), and information on CYP2C19 genotype were - included. DATA EXTRACTION: We extracted information on study design, genotyping, - and disease outcomes and investigated sources of bias. RESULTS: We retrieved 32 - studies of 42,016 patients reporting 3545 CVD events, 579 stent thromboses, and - 1413 bleeding events. Six studies were randomized trials ("effect-modification" - design) and the remaining 26 reported individuals exposed to clopidogrel - ("treatment-only" design). In treatment-only analysis, individuals with 1 or more - CYP2C19 alleles associated with lower enzyme activity had lower levels of active - clopidogrel metabolites, less platelet inhibition, lower risk of bleeding - (relative risk [RR], 0.84; 95% CI, 0.75-0.94; absolute risk reduction of 5-8 - events per 1000 individuals), and higher risk of CVD events (RR, 1.18; 95% CI, - 1.09-1.28; absolute risk increase of 8-12 events per 1000 individuals). However, - there was evidence of small-study bias (Harbord test P = .001). When analyses - were restricted to studies with 200 or more events, the point estimate was - attenuated (RR, 0.97; 95% CI, 0.86-1.09). In effect-modification studies, CYP2C19 - genotype was not associated with modification of the effect of clopidogrel on CVD - end points or bleeding (P > .05 for interaction for both). Other limitations - included selective outcome reporting and potential for genotype misclassification - due to problems with the * allele nomenclature for cytochrome enzymes. - CONCLUSION: Although there was an association between the CYP2C19 genotype and - clopidogrel responsiveness, overall there was no significant association of - genotype with cardiovascular events. -FAU - Holmes, Michael V -AU - Holmes MV -AD - Genetic Epidemiology Group, Department of Epidemiology and Public Health, - University College London, 1-19 Torrington Pl, London, WC1E 6BT, United Kingdom. - mvholmes@gmail.com -FAU - Perel, Pablo -AU - Perel P -FAU - Shah, Tina -AU - Shah T -FAU - Hingorani, Aroon D -AU - Hingorani AD -FAU - Casas, Juan P -AU - Casas JP -LA - eng -GR - RP-PG-0407-10314/DH_/Department of Health/United Kingdom -GR - FS 05/125/BHF_/British Heart Foundation/United Kingdom -GR - G0802432/MRC_/Medical Research Council/United Kingdom -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - United States -TA - JAMA -JT - JAMA -JID - 7501160 -RN - 0 (Platelet Aggregation Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - EC 1.14.14.1 (Aryl Hydrocarbon Hydroxylases) -RN - EC 1.14.14.1 (CYP2C19 protein, human) -RN - EC 1.14.14.1 (Cytochrome P-450 CYP2C19) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -CIN - JAMA. 2011 Dec 28;306(24):2727-8. doi: 10.1001/jama.2011.1865. PMID: 22203545 -CIN - JAMA. 2012 Apr 11;307(14):1482; author reply 1484-5. doi: 10.1001/jama.2012.443. - PMID: 22496255 -CIN - JAMA. 2012 Apr 11;307(14):1482-3; author reply 1484-5. doi: - 10.1001/jama.2012.444. PMID: 22496256 -CIN - JAMA. 2012 Apr 11;307(14):1483-4; author reply 1484-5. doi: - 10.1001/jama.2012.445. PMID: 22496257 -MH - Angioplasty, Balloon, Coronary -MH - Aryl Hydrocarbon Hydroxylases/*genetics -MH - Cardiovascular Diseases/*epidemiology -MH - Clopidogrel -MH - Cytochrome P-450 CYP2C19 -MH - Genotype -MH - Hemorrhage/*epidemiology -MH - Humans -MH - Platelet Aggregation/*drug effects -MH - Platelet Aggregation Inhibitors/adverse - effects/*metabolism/pharmacology/therapeutic use -MH - Platelet Function Tests -MH - Randomized Controlled Trials as Topic -MH - Risk -MH - Thrombosis/prevention & control -MH - Ticlopidine/adverse effects/*analogs & - derivatives/metabolism/pharmacology/therapeutic use -EDAT- 2011/12/29 06:00 -MHDA- 2011/12/30 06:00 -CRDT- 2011/12/29 06:00 -PHST- 2011/12/29 06:00 [entrez] -PHST- 2011/12/29 06:00 [pubmed] -PHST- 2011/12/30 06:00 [medline] -AID - 306/24/2704 [pii] -AID - 10.1001/jama.2011.1880 [doi] -PST - ppublish -SO - JAMA. 2011 Dec 28;306(24):2704-14. doi: 10.1001/jama.2011.1880. - -PMID- 21567995 -OWN - NLM -STAT- MEDLINE -DCOM- 20110718 -LR - 20191112 -IS - 1741-8275 (Electronic) -IS - 1741-8267 (Linking) -VI - 18 -IP - 2 -DP - 2011 Apr -TI - Strategies for the prevention of sudden cardiac death during sports. -PG - 197-208 -AB - Sudden cardiac death of a young athlete is the most tragic event in sports and - devastates the family, the sports medicine team, and the local community. Such a - fatality represents the first manifestation of cardiac disease in up to 80% of - young athletes who remain asymptomatic before sudden cardiac arrest occurs; this - explains the limited power of screening modalities based solely on history and - physical examination. The long-running Italian experience showed that - electrocardiogram (ECG) screening definitively improves the sensitivity of - pre-participation evaluation for heart diseases and substantially reduces the - risk of death in the athletic field (primary prevention). However, some cardiac - conditions, such as coronary artery diseases, present no abnormalities on 12-lead - ECG. Moreover, cardiac arrest due to non-penetrating chest injury (commotio - cordis) cannot be prevented by screening. This justifies the efforts for - implementing programmes of early external defibrillation of unpredictable - arrhythmic cardiac arrest. This article reviews the epidemiology of sudden - cardiac arrest in the athlete in terms of incidence, sport-related risk, - underlying causes, and the currently available prevention programmes such as - pre-participation screening and early external defibrillation by using automated - external defibrillators. The best strategy is to combine synergistically primary - prevention of sudden cardiac death by pre-participation identification of - athletes affected by at-risk cardiomyopathies and secondary prevention with - back-up defibrillation of unpredictable sudden cardiac arrest on the athletic - field. -FAU - Corrado, Domenico -AU - Corrado D -AD - Division of Cardiology, Department of Cardiac, Thoracic and Vascular Sciences, - University of Padova, Via Giustiniani 2, Padua, Italy. domenico.corrado@unipd.it -FAU - Drezner, Jonathan -AU - Drezner J -FAU - Basso, Cristina -AU - Basso C -FAU - Pelliccia, Antonio -AU - Pelliccia A -FAU - Thiene, Gaetano -AU - Thiene G -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Eur J Cardiovasc Prev Rehabil -JT - European journal of cardiovascular prevention and rehabilitation : official - journal of the European Society of Cardiology, Working Groups on Epidemiology & - Prevention and Cardiac Rehabilitation and Exercise Physiology -JID - 101192000 -SB - IM -CIN - Eur J Cardiovasc Prev Rehabil. 2011 Apr;18(2):194-6. doi: - 10.1177/1741826710389374. PMID: 21450665 -MH - Adult -MH - Death, Sudden, Cardiac/epidemiology/etiology/*prevention & control -MH - Defibrillators -MH - Electric Countershock/instrumentation -MH - Electrocardiography -MH - Female -MH - Heart Diseases/complications/diagnosis/epidemiology/*therapy -MH - Humans -MH - Incidence -MH - Male -MH - Mass Screening -MH - *Preventive Health Services/methods -MH - Risk Assessment -MH - Risk Factors -MH - *Sports -MH - Young Adult -EDAT- 2011/05/14 06:00 -MHDA- 2011/07/19 06:00 -CRDT- 2011/05/14 06:00 -PHST- 2011/05/14 06:00 [entrez] -PHST- 2011/05/14 06:00 [pubmed] -PHST- 2011/07/19 06:00 [medline] -AID - 10.1177/1741826710389924 [doi] -PST - ppublish -SO - Eur J Cardiovasc Prev Rehabil. 2011 Apr;18(2):197-208. doi: - 10.1177/1741826710389924. - -PMID- 18977991 -OWN - NLM -STAT- MEDLINE -DCOM- 20081125 -LR - 20250529 -IS - 1098-4275 (Electronic) -IS - 0031-4005 (Print) -IS - 0031-4005 (Linking) -VI - 122 -IP - 5 -DP - 2008 Nov -TI - Pediatric cardiopulmonary resuscitation: advances in science, techniques, and - outcomes. -PG - 1086-98 -LID - 10.1542/peds.2007-3313 [doi] -AB - More than 25% of children survive to hospital discharge after in-hospital cardiac - arrests, and 5% to 10% survive after out-of-hospital cardiac arrests. This review - of pediatric cardiopulmonary resuscitation addresses the epidemiology of - pediatric cardiac arrests, mechanisms of coronary blood flow during - cardiopulmonary resuscitation, the 4 phases of cardiac arrest resuscitation, - appropriate interventions during each phase, special resuscitation circumstances, - extracorporeal membrane oxygenation cardiopulmonary resuscitation, and quality of - cardiopulmonary resuscitation. The key elements of pathophysiology that impact - and match the timing, intensity, duration, and variability of the - hypoxic-ischemic insult to evidence-based interventions are reviewed. Exciting - discoveries in basic and applied-science laboratories are now relevant for - specific subpopulations of pediatric cardiac arrest victims and circumstances - (eg, ventricular fibrillation, neonates, congenital heart disease, extracorporeal - cardiopulmonary resuscitation). Improving the quality of interventions is - increasingly recognized as a key factor for improving outcomes. Evolving training - strategies include simulation training, just-in-time and just-in-place training, - and crisis-team training. The difficult issue of when to discontinue - resuscitative efforts is addressed. Outcomes from pediatric cardiac arrests are - improving. Advances in resuscitation science and state-of-the-art implementation - techniques provide the opportunity for further improvement in outcomes among - children after cardiac arrest. -FAU - Topjian, Alexis A -AU - Topjian AA -AD - Department of Anesthesia and Critical Care Medicine, University of Pennsylvania, - Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA. - topjian@email.chop.edu -FAU - Berg, Robert A -AU - Berg RA -FAU - Nadkarni, Vinay M -AU - Nadkarni VM -LA - eng -GR - R01 HL071694/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Review -PL - United States -TA - Pediatrics -JT - Pediatrics -JID - 0376422 -RN - 0 (Nerve Growth Factors) -RN - 0 (S100 Calcium Binding Protein beta Subunit) -RN - 0 (S100 Proteins) -SB - IM -MH - Animals -MH - Blood Pressure -MH - *Cardiopulmonary Resuscitation -MH - Child -MH - Extracorporeal Membrane Oxygenation -MH - Heart Arrest/epidemiology/mortality/physiopathology/*therapy -MH - Humans -MH - Infant, Newborn -MH - Infant, Premature -MH - Life Support Care -MH - Magnetic Resonance Imaging -MH - Nerve Growth Factors/blood -MH - No-Reflow Phenomenon/physiopathology -MH - Prognosis -MH - Quality of Life -MH - Regional Blood Flow -MH - S100 Calcium Binding Protein beta Subunit -MH - S100 Proteins/blood -MH - Vascular Resistance -MH - Ventricular Fibrillation/epidemiology/physiopathology -PMC - PMC2680157 -MID - NIHMS99922 -EDAT- 2008/11/04 09:00 -MHDA- 2008/12/17 09:00 -PMCR- 2009/11/01 -CRDT- 2008/11/04 09:00 -PHST- 2008/11/04 09:00 [pubmed] -PHST- 2008/12/17 09:00 [medline] -PHST- 2008/11/04 09:00 [entrez] -PHST- 2009/11/01 00:00 [pmc-release] -AID - 122/5/1086 [pii] -AID - 10.1542/peds.2007-3313 [doi] -PST - ppublish -SO - Pediatrics. 2008 Nov;122(5):1086-98. doi: 10.1542/peds.2007-3313. - -PMID- 21128810 -OWN - NLM -STAT- MEDLINE -DCOM- 20110111 -LR - 20211209 -IS - 1938-5404 (Electronic) -IS - 0033-7587 (Linking) -VI - 174 -IP - 6 -DP - 2010 Dec -TI - Vascular damage as an underlying mechanism of cardiac and cerebral toxicity in - irradiated cancer patients. -PG - 865-9 -LID - 10.1667/RR1862.1 [doi] -AB - Radiation is an independent risk factor for cardiovascular and cerebrovascular - disease in cancer patients. Modern radiotherapy techniques reduce the volume of - the heart and major coronary vessels exposed to high doses, but some exposure is - often unavoidable. Radiation damage to the myocardium is caused primarily by - inflammatory changes in the microvasculature, leading to microthrombi and - occlusion of vessels, reduced vascular density, perfusion defects and focal - ischemia. This is followed by progressive myocardial cell death and fibrosis. - Clinical studies also demonstrate regional perfusion defects in non-symptomatic - breast cancer patients after radiotherapy. The incidence and extent of perfusion - defects are related to the volume of left ventricle included in the radiation - field. Irradiation of endothelial cells lining large vessels also increases - expression of inflammatory molecules, leading to adhesion and transmigration of - circulating monocytes. In the presence of elevated cholesterol, invading - monocytes transform into activated macrophages and form fatty streaks in the - intima, thereby initiating the process of atherosclerosis. Experimental studies - have shown that radiation predisposes to the formation of inflammatory plaque, - which is more likely to rupture and cause a fatal heart attack or stroke. This - paper presents a brief overview of the current knowledge on mechanisms for - development of radiation-induced cardiovascular and cerebrovascular damage. It - does not represent a comprehensive review of the literature, but reference is - made to several excellent recent reviews on the topic. -FAU - Stewart, F A -AU - Stewart FA -AD - Division of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam, - The Netherlands. f.stewart@nki.nl -FAU - Hoving, S -AU - Hoving S -FAU - Russell, N S -AU - Russell NS -LA - eng -PT - Journal Article -PT - Review -DEP - 20100830 -PL - United States -TA - Radiat Res -JT - Radiation research -JID - 0401245 -SB - IM -MH - Atherosclerosis/etiology -MH - Blood Vessels/*radiation effects -MH - Cardiovascular Diseases/*etiology -MH - Cerebrovascular Disorders/*etiology -MH - Endothelial Cells/*radiation effects -MH - Humans -MH - Microvessels/radiation effects -MH - Neoplasms/*radiotherapy -MH - Radiotherapy/adverse effects -MH - Telangiectasis/etiology -EDAT- 2010/12/07 06:00 -MHDA- 2011/01/12 06:00 -CRDT- 2010/12/07 06:00 -PHST- 2010/12/07 06:00 [entrez] -PHST- 2010/12/07 06:00 [pubmed] -PHST- 2011/01/12 06:00 [medline] -AID - 10.1667/RR1862.1 [pii] -AID - 10.1667/RR1862.1 [doi] -PST - ppublish -SO - Radiat Res. 2010 Dec;174(6):865-9. doi: 10.1667/RR1862.1. Epub 2010 Aug 30. - -PMID- 23207414 -OWN - NLM -STAT- MEDLINE -DCOM- 20131122 -LR - 20170306 -VI - 122 -IP - 11 -DP - 2012 -TI - Therapeutic problems in elderly patients with hemophilia. -PG - 567-76 -AB - Since the introduction of clotting factor concentrates, the life expectancy of - patients with hemophilia has increased from 40 years in the 1960s to 60 or even - 70 years today. In Poland, almost all elderly patients with hemophilia have - arthropathy, the majority are infected with hepatitis C virus (HCV), and some - even with hepatitis B or human immunodeficiency virus. Liver cirrhosis associated - with HCV infection develops within 15 to 20 years in 20% to 30% of these - patients. Coexistent diseases related to aging and affecting the heart, kidneys, - and other organs constitute another challenge. To prevent ischemic heart disease, - cardiovascular risk factors should be carefully monitored. The present paper - describes the current recommendations for the use of antithrombotic therapy for - acute coronary syndromes and atrial fibrillation in patients with hemophilia. - Changes in the urinary system in hemophiliacs develop with age, often leading to - dialysis. There is an urgent need for intensive physiotherapy and improved access - to orthopedic treatment for patients with arthropathy. High‑risk surgical - procedures in these patients should be performed in specialized centers with an - experienced team and a coagulation laboratory. Older patients with mild - hemophilia are at an increased risk for inhibitor development following intensive - factor replacement therapy for surgical or invasive procedures. Pain control is a - particular challenge due to contraindications to the use of many effective - analgesics; another concern is the quality of life of these patients. An - increasing number of older patients with hemophilia requires a comprehensive - diagnostic and therapeutic approach, preferably at hematological centers. -FAU - Zawilska, Krystyna -AU - Zawilska K -AD - Department of Hematology and Internal Diseases, Struś Hospital, Poznań, Poland. - k.zawilska@interia.pl -FAU - Podolak-Dawidziak, Maria -AU - Podolak-Dawidziak M -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Pol Arch Med Wewn -JT - Polskie Archiwum Medycyny Wewnetrznej -JID - 0401225 -SB - IM -MH - Aged -MH - Aging -MH - Cardiovascular Diseases/*epidemiology -MH - Comorbidity -MH - Female -MH - HIV Infections/*epidemiology -MH - Hemophilia A/*epidemiology -MH - Hepatitis C, Chronic/*epidemiology -MH - Humans -MH - Kidney Diseases/*epidemiology -MH - Male -MH - Middle Aged -MH - Musculoskeletal Diseases/*epidemiology -MH - Poland/epidemiology -MH - Prevalence -MH - Risk Factors -EDAT- 2012/12/05 06:00 -MHDA- 2013/12/16 06:00 -CRDT- 2012/12/05 06:00 -PHST- 2012/12/05 06:00 [entrez] -PHST- 2012/12/05 06:00 [pubmed] -PHST- 2013/12/16 06:00 [medline] -PST - ppublish -SO - Pol Arch Med Wewn. 2012;122(11):567-76. - -PMID- 20956616 -OWN - NLM -STAT- MEDLINE -DCOM- 20110502 -LR - 20200206 -IS - 1569-8041 (Electronic) -IS - 0923-7534 (Linking) -VI - 22 -IP - 2 -DP - 2011 Feb -TI - Anthracycline cardiotoxicity in the elderly cancer patient: a SIOG expert - position paper. -PG - 257-67 -LID - 10.1093/annonc/mdq609 [doi] -AB - BACKGROUND: Comorbidities and risk factors likely to complicate treatment are - common in elderly cancer patients. Anthracyclines remain the cornerstone of - first-line therapy for non-Hodgkin's lymphoma (NHL) and metastatic and early - breast cancer but can cause congestive heart failure. Elderly patients are at - increased risk of this event and measures to reduce it should be considered. - METHODS: A committee of experts in breast cancer and NHL met under the auspices - of the International Society for Geriatric Oncology to review the literature and - make recommendations, based on level of evidence, for the assessment, treatment - and monitoring of elderly patients requiring anthracyclines. RESULTS AND - RECOMMENDATIONS: Use of anthracycline-based chemotherapy illustrates many of the - dilemmas facing elderly cancer patients. Age in itself should not prevent access - to potentially curative treatment or treatment that prolongs life or improves its - quality. The risk of cardiotoxicity with conventional anthracyclines is increased - by the following factors: an existing or history of heart failure or cardiac - dysfunction; hypertension, diabetes and coronary artery disease; older age - (independent of comorbidities and performance status); prior treatment with - anthracyclines; higher cumulative dose of anthracyclines and short infusion - duration. The fact that cumulative and irreversible cardiotoxicity is likely to - be greater in this population than among younger patients calls for effective - pretreatment screening for risk factors, rigorous monitoring of cardiac function - and early intervention. Use of liposomal anthracycline formulations, prolonging - the infusion time for conventional anthracyclines and cardioprotective measures - should be considered. However, when treatment is being given with curative - intent, care should be taken to ensure reduced cardiotoxicity is not achieved at - the expense of efficacy. -FAU - Aapro, M -AU - Aapro M -AD - Institut Multidisciplinaire d'Oncologie, Clinique de Genolier, Genolier, - Switzerland. -FAU - Bernard-Marty, C -AU - Bernard-Marty C -FAU - Brain, E G C -AU - Brain EG -FAU - Batist, G -AU - Batist G -FAU - Erdkamp, F -AU - Erdkamp F -FAU - Krzemieniecki, K -AU - Krzemieniecki K -FAU - Leonard, R -AU - Leonard R -FAU - Lluch, A -AU - Lluch A -FAU - Monfardini, S -AU - Monfardini S -FAU - Ryberg, M -AU - Ryberg M -FAU - Soubeyran, P -AU - Soubeyran P -FAU - Wedding, U -AU - Wedding U -LA - eng -PT - Journal Article -PT - Review -DEP - 20101018 -PL - England -TA - Ann Oncol -JT - Annals of oncology : official journal of the European Society for Medical - Oncology -JID - 9007735 -RN - 0 (Anthracyclines) -RN - 0 (Antineoplastic Agents) -SB - IM -MH - Adult -MH - Aged -MH - Anthracyclines/*adverse effects -MH - Antineoplastic Agents/*adverse effects -MH - Humans -MH - Middle Aged -MH - Neoplasms/drug therapy -EDAT- 2010/10/20 06:00 -MHDA- 2011/05/03 06:00 -CRDT- 2010/10/20 06:00 -PHST- 2010/10/20 06:00 [entrez] -PHST- 2010/10/20 06:00 [pubmed] -PHST- 2011/05/03 06:00 [medline] -AID - S0923-7534(19)38676-4 [pii] -AID - 10.1093/annonc/mdq609 [doi] -PST - ppublish -SO - Ann Oncol. 2011 Feb;22(2):257-67. doi: 10.1093/annonc/mdq609. Epub 2010 Oct 18. - -PMID- 23027453 -OWN - NLM -STAT- MEDLINE -DCOM- 20130110 -LR - 20141120 -IS - 0171-2004 (Print) -IS - 0171-2004 (Linking) -IP - 214 -DP - 2012 -TI - Sex and gender differences in cardiovascular drug therapy. -PG - 211-36 -LID - 10.1007/978-3-642-30726-3_11 [doi] -AB - This chapter outlines sex differences in pharmacokinetics and pharmacodynamics of - the most frequently used drugs in cardiovascular diseases, e.g., coronary artery - disease, hypertension, heart failure. Retrospective analysis of previously - published drug trials revealed marked sex differences in efficacy and adverse - effects in a number of cardiovascular drugs. This includes a higher mortality - among women taking digoxin for heart failure, more torsade de pointes arrhythmia - in QT prolonging drugs and more cough with ACE inhibitors. Trends towards a - greater benefit for women and/or female animals have been observed in some - studies for endothelin receptor antagonists, the calcium channel blocker - amlodipine, the ACE-inhibitor ramipril and the aldosterone antagonist eplerenone. - However, reproduction of these results in independent studies and solid - statistical evidence is still lacking. Some drugs require a particularly careful - dose adaptation in women: the beta-blocker metoprolol, the calcium channel - blocker verapamil, loop-, and thiazide diuretics. In conclusion, sex differences - in pharmacokinetics and pharmacodynamics have to be taken into account for - cardiovascular drug therapy in women. -FAU - Seeland, Ute -AU - Seeland U -AD - Institute of Gender in Medicine, Universitaetsmedizin Berlin Charité, Berlin, - Germany. -FAU - Regitz-Zagrosek, Vera -AU - Regitz-Zagrosek V -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Handb Exp Pharmacol -JT - Handbook of experimental pharmacology -JID - 7902231 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin Receptor Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Endothelin Receptor Antagonists) -RN - 0 (Gonadal Steroid Hormones) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin Receptor Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Calcium Channel Blockers/therapeutic use -MH - Cardiovascular Diseases/*drug therapy -MH - Endothelin Receptor Antagonists -MH - Female -MH - Gonadal Steroid Hormones/physiology -MH - Humans -MH - Male -MH - Polymorphism, Genetic -MH - *Sex Characteristics -EDAT- 2012/10/03 06:00 -MHDA- 2013/01/11 06:00 -CRDT- 2012/10/03 06:00 -PHST- 2012/10/03 06:00 [entrez] -PHST- 2012/10/03 06:00 [pubmed] -PHST- 2013/01/11 06:00 [medline] -AID - 10.1007/978-3-642-30726-3_11 [doi] -PST - ppublish -SO - Handb Exp Pharmacol. 2012;(214):211-36. doi: 10.1007/978-3-642-30726-3_11. - -PMID- 22234024 -OWN - NLM -STAT- MEDLINE -DCOM- 20120511 -LR - 20121115 -IS - 0974-5181 (Electronic) -IS - 0971-9784 (Linking) -VI - 15 -IP - 1 -DP - 2012 Jan-Mar -TI - Anaesthetic management of transcatheter aortic valve implantation. -PG - 54-63 -LID - 10.4103/0971-9784.91484 [doi] -AB - Transcatheter aortic valve implantation (TAVI) is an emergent technique for - high-risk patients with aortic stenosis. TAVI poses significant challenges about - its management because of the procedure itself and the population who undergo the - implantation. Two devices are currently available and marketed in Europe and - several other technologies are being developed. The retrograde transfemoral - approach is the most popular procedure; nevertheless, it may not be feasible in - patients with significant aortic or ileo-femoral arterial disease. Alternatives - include a transaxillary approach, transapical approach, open surgical access to - the retroperitoneal iliac artery and the ascending aorta. A complementary - approach using both devices and alternative routes tailored to the anatomy and - the comorbidities of the single patient is a main component for the successful - implementation of a TAVI program. Anaesthetic strategies vary in different - centers. Local anaesthesia or general anaesthesia are both valid alternatives and - can be applied according to the patient's characteristics and procedural - instances. General anaesthesia offers many advantages, mainly regarding the - possibility of an early diagnosis and treatment of possible complications through - the use of transesophageal echocardiography. However, after the initial - experiences, many groups began to employ, routinely, sedation plus local - anaesthesia for TAVI, and their procedural and periprocedural success - demonstrates that it is feasible. TAVI is burdened with potential important - complications: vascular injuries, arrhythmias, renal impairment, neurological - complications, cardiac tamponade, prosthesis malpositioning and embolization and - left main coronary artery occlusion. The aim of this work is to review the - anaesthetic management of TAVI based on the available literature. -FAU - Franco, Annalisa -AU - Franco A -AD - Department of Cardiothoracic and Vascular Anaesthesia, Istituto Scientifico San - Raffaele, Milan, Italy. -FAU - Gerli, Chiara -AU - Gerli C -FAU - Ruggeri, Laura -AU - Ruggeri L -FAU - Monaco, Fabrizio -AU - Monaco F -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Ann Card Anaesth -JT - Annals of cardiac anaesthesia -JID - 9815987 -SB - IM -MH - Anesthesia/*methods -MH - Aortic Valve/*surgery -MH - Atrioventricular Block/etiology -MH - Cardiac Catheterization -MH - Cardiac Pacing, Artificial -MH - Echocardiography, Transesophageal -MH - *Heart Valve Prosthesis Implantation/adverse effects -MH - Humans -MH - Postoperative Complications/etiology -MH - Preoperative Care -EDAT- 2012/01/12 06:00 -MHDA- 2012/05/12 06:00 -CRDT- 2012/01/12 06:00 -PHST- 2012/01/12 06:00 [entrez] -PHST- 2012/01/12 06:00 [pubmed] -PHST- 2012/05/12 06:00 [medline] -AID - AnnCardAnaesth_2012_15_1_54_91484 [pii] -AID - 10.4103/0971-9784.91484 [doi] -PST - ppublish -SO - Ann Card Anaesth. 2012 Jan-Mar;15(1):54-63. doi: 10.4103/0971-9784.91484. - -PMID- 22420013 -STAT- Publisher -PB - Royal College of Physicians (UK) -CTI - National Institute for Health and Clinical Excellence: Guidance -DP - 2010 Mar -BTI - Chest Pain of Recent Onset: Assessment and Diagnosis of Recent Onset Chest Pain - or Discomfort of Suspected Cardiac Origin -AB - Chest pain or discomfort caused by acute coronary syndromes (ACS) or angina has a - potentially poor prognosis, emphasising the importance of prompt and accurate - diagnosis. Treatments are available to improve symptoms and prolong life, hence - the need for this guideline. This guideline covers the assessment and diagnosis - of people with recent onset chest pain or discomfort of suspected cardiac origin. - In deciding whether chest pain may be cardiac and therefore whether this - guideline is relevant, a number of factors should be taken into account. These - include the person's history of chest pain, their cardiovascular risk factors, - history of ischaemic heart disease and any previous treatment, and previous - investigations for chest pain. For pain that is suspected to be cardiac, there - are two separate diagnostic pathways presented in the guideline. The first is for - people with acute chest pain in whom ACS is suspected, and the second is for - people with intermittent stable chest pain in whom stable angina is suspected. - The guideline includes how to determine whether myocardial ischaemia is the cause - of the chest pain and how to manage the chest pain while people are being - assessed and investigated. The diagnosis and management of chest pain that is - clearly unrelated to the heart (e.g. traumatic chest wall injury, herpes zoster - infection) is not considered once myocardial ischaemia has been excluded. The - guideline makes no assumptions about who the patient consults, where that - consultation takes place (primary care, secondary care, emergency department) or - what diagnostic facilities might be available. It recognizes that while - atherosclerotic CAD is the usual cause of angina and ACS, it is not a necessary - requirement for either diagnosis. Similarly, it recognises that in patients with - a prior diagnosis of CAD, chest pain or discomfort is not necessarily cardiac in - origin. -CI - Copyright © 2010, National Clinical Guideline Centre for Acute and Chronic - Conditions. -CN - National Clinical Guideline Centre for Acute and Chronic Conditions (UK) -LA - eng -PT - Practice Guideline -PT - Review -PT - Book -PL - London -EDAT- 2010/03/01 00:00 -CRDT- 2010/03/01 00:00 -AID - NBK63790 [bookaccession] - -PMID- 18198964 -OWN - NLM -STAT- MEDLINE -DCOM- 20080207 -LR - 20191110 -IS - 0888-5109 (Print) -IS - 0888-5109 (Linking) -VI - 22 -IP - 8 -DP - 2007 Aug -TI - Cardiovascular medication prescribing in older adults with psychiatric disorders. -PG - 660-8 -AB - OBJECTIVES: To examine the appropriateness of cardiovascular (CV) medication - prescribing of patients admitted to a geriatric psychiatry ward. Secondary aims - included examining: 1) if differences in CV medication prescribing existed - between admission and discharge and 2) if differences in CV medication - prescribing existed between patients with and without dementia. DESIGN: - Cross-sectional study. SETTING: Inpatient geriatric psychiatry unit within a - regional medical center. PATIENTS: 197 patients admitted between June 2005 and - May 2006. INTERVENTIONS: Changes in CV medication prescribing from admission to - discharge. MEASURES AND RESULTS: On admission, the percent of patients receiving - appropriate CV medications for general CV prevention, atrial fibrillation, - coronary-artery disease, and heart failure ranged from 33% to 56%. With the - exception of the treatment of heart failure, no significant improvements in - appropriate CV medication prescribing were noted at the time of discharge. No - differences in CV medication prescribing were found between patients with and - without dementia. CONCLUSION: Despite the known benefits of numerous CV - medications in older adults, many patients admitted to a geriatric psychiatry - ward were not prescribed optimal pharmacotherapeutic regimens on admission or had - their medications changed by the time of discharge. -FAU - Dolder, Christian R -AU - Dolder CR -AD - Wingate University School of Pharmacy, Wingate, NC 28174, USA. - cdolder@wingate.edu -FAU - Veverka, Angie -AU - Veverka A -FAU - Nuzum, Donald S -AU - Nuzum DS -FAU - McKinsey, Jonathan -AU - McKinsey J -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Consult Pharm -JT - The Consultant pharmacist : the journal of the American Society of Consultant - Pharmacists -JID - 9013983 -RN - 0 (Cardiovascular Agents) -SB - IM -MH - Aged -MH - Cardiovascular Agents/*therapeutic use -MH - Cardiovascular Diseases/complications/*drug therapy -MH - Cross-Sectional Studies -MH - Dementia/*complications -MH - Drug Monitoring -MH - Drug Utilization -MH - Female -MH - Humans -MH - Male -MH - North Carolina -MH - Patient Admission/statistics & numerical data -MH - Patient Discharge/statistics & numerical data -MH - *Practice Patterns, Physicians' -MH - Psychiatric Department, Hospital -RF - 53 -EDAT- 2008/01/18 09:00 -MHDA- 2008/02/08 09:00 -CRDT- 2008/01/18 09:00 -PHST- 2008/01/18 09:00 [pubmed] -PHST- 2008/02/08 09:00 [medline] -PHST- 2008/01/18 09:00 [entrez] -AID - 10.4140/tcp.n.2007.660 [doi] -PST - ppublish -SO - Consult Pharm. 2007 Aug;22(8):660-8. doi: 10.4140/tcp.n.2007.660. - -PMID- 17882744 -OWN - NLM -STAT- MEDLINE -DCOM- 20070925 -LR - 20161124 -IS - 1439-4413 (Electronic) -IS - 0012-0472 (Linking) -VI - 132 -IP - 39 -DP - 2007 Sep -TI - [Stress-ECG is adequate to detect myocardial ischemia: when are additional - diagnostic tests needed?]. -PG - 2026-30 -AB - The stress-ECG is the most often adopted and most cost effective initial - diagnostic test for the assessment of myocardial ischemia in patients with - suspected coronary artery disease (CAD). Prerequisites for the diagnostic - usefullness of stress-ECG are a clearly interpretable ST-segment, ability to - reach the predicted work load, an intermediate pretest probability for CAD - ranging between 10% and 90% and the absence of any contraindications for dynamic - exercise. Because of the limited diagnostic sensitivity of about 70%, and a high - percentage of patients, who are unable to exercise, a negative stress ECG can - definitely not exclude hemodynamically significant CAD. Therefore, stress imaging - techniques like myocardial scintigraphy, stress-echocardiography and stress - magnetic resonance imaging play a major role in the stepwise diagnostic work-up - of patients with suspected CAD. These stress imaging techniques are basically - interchangeable since no method is definitely superior to one of the others. - However, each method has its specific pros and cons and inherent - contraindications. Therefore the choice of the stress imaging method and the form - of stress applied should be based on the individual patients characteristics to - gain optimal image quality and diagnostic accuracy. Moreover, the decision for - one method should take the local availability and institutional expertise of - diagnostic centers into account. Although partly substituted by stress imaging - techniques the stress-ECG still remains the workhorse for a stepwise diagnostic - work-up of patients with suspected CAD. -FAU - Baer, F M -AU - Baer FM -AD - Klinik III für Innere Medizin der Universität zu Köln. frank.baer@uni-koeln.de -LA - ger -PT - Journal Article -PT - Review -TT - Zum Ischämienachweis reicht das Belastungs-EKG: Wann sollten andere Verfahren - eingesetzt werden? -PL - Germany -TA - Dtsch Med Wochenschr -JT - Deutsche medizinische Wochenschrift (1946) -JID - 0006723 -SB - IM -MH - Echocardiography, Stress -MH - Electrocardiography/*methods -MH - *Exercise Test -MH - Heart/diagnostic imaging -MH - Humans -MH - Magnetic Resonance Imaging/methods -MH - Myocardial Ischemia/*diagnosis/physiopathology -MH - Radionuclide Imaging -RF - 19 -EDAT- 2007/09/21 09:00 -MHDA- 2007/09/26 09:00 -CRDT- 2007/09/21 09:00 -PHST- 2007/09/21 09:00 [pubmed] -PHST- 2007/09/26 09:00 [medline] -PHST- 2007/09/21 09:00 [entrez] -AID - 10.1055/s-2007-985638 [doi] -PST - ppublish -SO - Dtsch Med Wochenschr. 2007 Sep;132(39):2026-30. doi: 10.1055/s-2007-985638. - -PMID- 19555834 -OWN - NLM -STAT- MEDLINE -DCOM- 20090723 -LR - 20220317 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 54 -IP - 1 -DP - 2009 Jun 30 -TI - Cardiac positron emission tomography. -PG - 1-15 -LID - 10.1016/j.jacc.2009.02.065 [doi] -AB - Positron emission tomography (PET) is a powerful, quantitative imaging modality - that has been used for decades to noninvasively investigate cardiovascular - biology and physiology. Due to limited availability, methodologic complexity, and - high costs, it has long been seen as a research tool and as a reference method - for validation of other diagnostic approaches. This perception, fortunately, has - changed significantly within recent years. Increasing diversity of therapeutic - options for coronary artery disease, and increasing specificity of novel - therapies for certain biologic pathways, has resulted in a clinical need for more - accurate and specific diagnostic techniques. At the same time, the number of PET - centers continues to grow, stimulated by PET's success in oncology. Methodologic - advances as well as improved radiotracer availability have further contributed to - more widespread use. Evidence for diagnostic and prognostic usefulness of - myocardial perfusion and viability assessment by PET is increasing. Some studies - suggest overall cost-effectiveness of the technique despite higher costs of a - single study, because unnecessary follow-up procedures can be avoided. The advent - of hybrid PET-computed tomography (CT), which enables integration of PET-derived - biologic information with multislice CT-derived morphologic information, and the - key role of PET in the development and translation of novel molecular-targeted - imaging compounds, have further contributed to more widespread acceptance. Today, - PET promises to play a leading diagnostic role on the pathway toward a future of - high-powered, comprehensive, personalized, cardiovascular medicine. This review - summarizes the state-of-the-art in current imaging methodology and clinical - application, and outlines novel developments and future directions. -FAU - Bengel, Frank M -AU - Bengel FM -AD - Division of Nuclear Medicine/PET, Russell H. Morgan Department of Radiology and - Radiological Science, Johns Hopkins University, Baltimore, Maryland 21287, USA. - fbengel1@jhmi.edu -FAU - Higuchi, Takahiro -AU - Higuchi T -FAU - Javadi, Mehrbod S -AU - Javadi MS -FAU - Lautamäki, Riikka -AU - Lautamäki R -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Heart Diseases/*diagnosis -MH - Humans -MH - Positron-Emission Tomography/*trends -RF - 124 -EDAT- 2009/06/27 09:00 -MHDA- 2009/07/25 09:00 -CRDT- 2009/06/27 09:00 -PHST- 2008/11/13 00:00 [received] -PHST- 2009/01/27 00:00 [revised] -PHST- 2009/02/23 00:00 [accepted] -PHST- 2009/06/27 09:00 [entrez] -PHST- 2009/06/27 09:00 [pubmed] -PHST- 2009/07/25 09:00 [medline] -AID - S0735-1097(09)01172-3 [pii] -AID - 10.1016/j.jacc.2009.02.065 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2009 Jun 30;54(1):1-15. doi: 10.1016/j.jacc.2009.02.065. - -PMID- 19144653 -OWN - NLM -STAT- MEDLINE -DCOM- 20100218 -LR - 20100122 -IS - 1940-1574 (Electronic) -IS - 0003-3197 (Linking) -VI - 60 -IP - 6 -DP - 2009 Dec-2010 Jan -TI - On target to dual block RAS? -PG - 739-49 -LID - 10.1177/0003319708329799 [doi] -AB - Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are - thought to possess cardioprotective, cerebroprotective, and nephroprotective - properties. Both classes of agents can prevent or reverse endothelial dysfunction - and atherosclerosis, thereby potentially reducing the risk of cardiovascular - events. Such a reduction has been shown with angiotensin-converting enzyme - inhibitors in patients with coronary artery disease, but no such data are scarce - with angiotensin receptor blockers (Valsartan in Acute Myocardial Infarction - study). Both angiotensin-converting enzyme inhibitors and angiotensin receptor - blockers have been shown to reduce damage in target organs, such as the heart and - kidney, and to decrease cardiovascular mortality and morbidity in patients with - congestive heart failure. These drugs (especially angiotensin receptor blockers) - may successfully prevent atrial fibrillation and play a protective role in - metabolic syndrome. In some clinical settings, combined therapy - angiotensin-converting enzyme inhibitors with angiotensin receptor blocker - (double blockade of the renin-angiotensin- aldosterone system) may appear the - most effective. -FAU - Papadopoulos, Dimitris P -AU - Papadopoulos DP -AD - Hypertension Clinic, Department of Cardiology, Laiko Hospital, Athens, Greece. - jimpapdoc@yahoo.com -FAU - Papademetriou, Vasilios -AU - Papademetriou V -FAU - Makris, Thomas K -AU - Makris TK -LA - eng -PT - Journal Article -PT - Review -DEP - 20090113 -PL - United States -TA - Angiology -JT - Angiology -JID - 0203706 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/*therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/*therapeutic use -MH - Cardiovascular Diseases/metabolism/*prevention & control -MH - Humans -MH - Renin-Angiotensin System/*drug effects -RF - 65 -EDAT- 2009/01/16 09:00 -MHDA- 2010/02/19 06:00 -CRDT- 2009/01/16 09:00 -PHST- 2009/01/16 09:00 [entrez] -PHST- 2009/01/16 09:00 [pubmed] -PHST- 2010/02/19 06:00 [medline] -AID - 0003319708329799 [pii] -AID - 10.1177/0003319708329799 [doi] -PST - ppublish -SO - Angiology. 2009 Dec-2010 Jan;60(6):739-49. doi: 10.1177/0003319708329799. Epub - 2009 Jan 13. - -PMID- 16562568 -OWN - NLM -STAT- MEDLINE -DCOM- 20060713 -LR - 20191109 -IS - 0887-2171 (Print) -IS - 0887-2171 (Linking) -VI - 27 -IP - 1 -DP - 2006 Feb -TI - MRI assessment of myocardial viability. -PG - 11-9 -AB - In the presence of coronary artery disease, global left ventricular (LV) systolic - function is a critical prognostic indicator. Because of enhanced therapy for - myocardial infarction, more patients survive but are left with residual - myocardial damage that predisposes them to developing CHF in the future. Although - treatments for CHF are evolving, preventing and minimizing further deteriorations - in LV function are paramount in this population. Distinguishing severe LV - dysfunction caused by thinned, infarcted myocardium with fibrosis and scarring - from that due to viable but dysfunctional myocardium from chronic hypoperfusion - has significant implications for clinical management. In patients in whom - noninvasive testing identifies viability, undergoing revascularization improves - outcomes. Noninvasive imaging techniques used to assess viable myocardium are - based on demonstrating the presence of one or more of the following features: (1) - contractile reserve; (2) sufficient perfusion for the delivery of substrates and - removal of metabolic byproducts; (3) intact myocyte membranes to maintain - ionic/electrochemical gradients; and (4) preserved metabolism with generation of - high-energy phosphates. While nuclear and dobutamine echocardiography have been - widely used for viability assessment, cardiac magnetic resonance imaging (CMR) is - increasingly becoming an accepted clinical tool, particularly in light of its - high spatial resolution, intrinsic ability to image 3-dimensionally, and greater - soft tissue differentiation. Moreover, the versatility of the technique - potentially allows for the simultaneous assessment of regional wall motion, - perfusion, and metabolism. An overview of the CMR techniques is presented. -FAU - Schmidt, Andre -AU - Schmidt A -AD - Division of Cardiology, Department of Medicine, Johns Hopkins University, - Baltimore, MD 21287, USA. -FAU - Wu, Katherine C -AU - Wu KC -LA - eng -GR - K23 HL04444/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Semin Ultrasound CT MR -JT - Seminars in ultrasound, CT, and MR -JID - 8504689 -RN - 0 (Contrast Media) -SB - IM -MH - Contrast Media -MH - Heart/*physiopathology -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Magnetic Resonance Spectroscopy/*methods -MH - Myocardial Contraction/physiology -RF - 76 -EDAT- 2006/03/28 09:00 -MHDA- 2006/07/14 09:00 -CRDT- 2006/03/28 09:00 -PHST- 2006/03/28 09:00 [pubmed] -PHST- 2006/07/14 09:00 [medline] -PHST- 2006/03/28 09:00 [entrez] -AID - S0887-2171(05)00085-5 [pii] -AID - 10.1053/j.sult.2005.11.001 [doi] -PST - ppublish -SO - Semin Ultrasound CT MR. 2006 Feb;27(1):11-9. doi: 10.1053/j.sult.2005.11.001. - -PMID- 18460290 -OWN - NLM -STAT- MEDLINE -DCOM- 20080716 -LR - 20211020 -IS - 1546-9549 (Electronic) -IS - 1546-9530 (Linking) -VI - 5 -IP - 1 -DP - 2008 Mar -TI - CT for assessing ventricular remodeling: is it ready for prime time? -PG - 16-22 -AB - Reliable assessment of left ventricular size and systolic function has important - prognostic and therapeutic implications for patients with heart disease. CT - technology is advancing rapidly and can be used for noninvasive assessment of the - coronary anatomy. Without additional radiation or contrast, the already acquired - image data set can be used for analysis of left ventricular size, mass, and - systolic function. In comparison with other noninvasive modalities, multidetector - CT has superior spatial resolution but temporal resolution has suffered. Recent - advances, including multisegment reconstruction and dual-source scanning, have - improved the temporal resolution substantially. MRI is the current gold standard - for assessing the left ventricle. Many small comparative studies suggest that CT - has good agreement with MRI and that it could potentially replace MRI in some - patients, especially those with internal cardiac devices. The use of CT to assess - ventricular remodeling is limited by the use of contrast and radiation, but its - widespread availability, ease of use, and improved temporal resolution suggest - that multidetector CT will have expansive use in the future. -FAU - Sigurdsson, Gardar -AU - Sigurdsson G -AD - Cardiology Division, Department of Medicine (111C), Veterans Affairs Medical - Center, One Veterans Drive, Minneapolis, MN 55417, USA. - Gardar.Sigurdsson@med.va.gov -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Heart Fail Rep -JT - Current heart failure reports -JID - 101196487 -SB - IM -MH - Female -MH - Forecasting -MH - Humans -MH - Male -MH - Radiographic Image Interpretation, Computer-Assisted -MH - Sensitivity and Specificity -MH - Tomography, X-Ray Computed/*methods/trends -MH - Ventricular Dysfunction, Left/*diagnostic imaging/physiopathology -MH - Ventricular Remodeling/*physiology -RF - 44 -EDAT- 2008/05/08 09:00 -MHDA- 2008/07/17 09:00 -CRDT- 2008/05/08 09:00 -PHST- 2008/05/08 09:00 [pubmed] -PHST- 2008/07/17 09:00 [medline] -PHST- 2008/05/08 09:00 [entrez] -AID - 10.1007/s11897-008-0004-2 [doi] -PST - ppublish -SO - Curr Heart Fail Rep. 2008 Mar;5(1):16-22. doi: 10.1007/s11897-008-0004-2. - -PMID- 20837571 -OWN - NLM -STAT- MEDLINE -DCOM- 20110930 -LR - 20220410 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 31 -IP - 20 -DP - 2010 Oct -TI - No-reflow: again prevention is better than treatment. -PG - 2449-55 -LID - 10.1093/eurheartj/ehq299 [doi] -FAU - Niccoli, Giampaolo -AU - Niccoli G -AD - Institute of Cardiology, Catholic University of Sacred Heart, L.go A. Gemelli, 8, - Rome 00168, Italy. gniccoli73@hotmail.it -FAU - Kharbanda, Rajesh K -AU - Kharbanda RK -FAU - Crea, Filippo -AU - Crea F -FAU - Banning, Adrian P -AU - Banning AP -LA - eng -PT - Journal Article -PT - Review -DEP - 20100913 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (Vasodilator Agents) -SB - IM -MH - Angioplasty, Balloon, Coronary/methods -MH - Coronary Restenosis/prevention & control -MH - Humans -MH - Microcirculation/physiology -MH - Myocardial Infarction/*therapy -MH - Myocardial Reperfusion -MH - Myocardial Reperfusion Injury/complications/*prevention & control -MH - Neutrophils/physiology -MH - No-Reflow Phenomenon/etiology/*prevention & control -MH - Vasodilator Agents/*therapeutic use -EDAT- 2010/09/15 06:00 -MHDA- 2011/10/01 06:00 -CRDT- 2010/09/15 06:00 -PHST- 2010/09/15 06:00 [entrez] -PHST- 2010/09/15 06:00 [pubmed] -PHST- 2011/10/01 06:00 [medline] -AID - ehq299 [pii] -AID - 10.1093/eurheartj/ehq299 [doi] -PST - ppublish -SO - Eur Heart J. 2010 Oct;31(20):2449-55. doi: 10.1093/eurheartj/ehq299. Epub 2010 - Sep 13. - -PMID- 16959586 -OWN - NLM -STAT- MEDLINE -DCOM- 20061103 -LR - 20060908 -IS - 0889-8529 (Print) -IS - 0889-8529 (Linking) -VI - 35 -IP - 3 -DP - 2006 Sep -TI - Peroxisome proliferator-activated receptor gamma agonists: their role as - vasoprotective agents in diabetes. -PG - 561-74, ix -AB - Both type 1 and type 2 diabetes melitius are associated with increased - cardiovascular morbidity, and now affect more than 170 million individuals - worldwide. The incidence of type 2 diabetes is growing rapidly and now accounts - for 90 to 95 percent of all diabetes cases. Thiazolidinediones (TZDs) a class of - insulin sensitizing agents commonly used in the treatment of patients who have - type 2 diabetes, improve endothelial dysfunction and exert beneficial effects on - lipid profiles by activating the nuclear receptor peroxisome - proliferator-activated receptor gamma (PPAR-gamma). In addition, TZDs exhibit - antiatherogenic effects, independent of their antidiabetic and lipid-lowering - properties, by attenuating proinflammatory processes. The combination of - increased insulin sensitivity, improved lipid profile, and reduced inflammation - may explain the cardiovascular benefits of this class of drugs -FAU - Blaschke, Florian -AU - Blaschke F -AD - Department of Endocrinology, Diabetes and Metabolism, Division of Endocrinology, - Diabetes and Hypertension, David Geffen School of Medicine, University of - California, Los Angeles, CA 90095, USA. -FAU - Caglayan, Evren -AU - Caglayan E -FAU - Hsueh, Willa A -AU - Hsueh WA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Endocrinol Metab Clin North Am -JT - Endocrinology and metabolism clinics of North America -JID - 8800104 -RN - 0 (Hypoglycemic Agents) -RN - 0 (PPAR gamma) -RN - 0 (Thiazolidinediones) -SB - IM -MH - Animals -MH - Atherosclerosis -MH - Coronary Restenosis -MH - Diabetes Mellitus, Type 1/complications -MH - Diabetes Mellitus, Type 2/complications/drug therapy -MH - Diabetic Angiopathies/*prevention & control -MH - Humans -MH - Hypoglycemic Agents/therapeutic use -MH - Inflammation -MH - Insulin Resistance -MH - Obesity/complications -MH - PPAR gamma/*agonists/physiology -MH - Thiazolidinediones/therapeutic use -RF - 110 -EDAT- 2006/09/09 09:00 -MHDA- 2006/11/04 09:00 -CRDT- 2006/09/09 09:00 -PHST- 2006/09/09 09:00 [pubmed] -PHST- 2006/11/04 09:00 [medline] -PHST- 2006/09/09 09:00 [entrez] -AID - S0889-8529(06)00041-7 [pii] -AID - 10.1016/j.ecl.2006.06.001 [doi] -PST - ppublish -SO - Endocrinol Metab Clin North Am. 2006 Sep;35(3):561-74, ix. doi: - 10.1016/j.ecl.2006.06.001. - -PMID- 18074531 -OWN - NLM -STAT- MEDLINE -DCOM- 20080227 -LR - 20110727 -IS - 0047-1852 (Print) -IS - 0047-1852 (Linking) -VI - 65 Suppl 8 -DP - 2007 Oct 28 -TI - [Adverse effects of calcium antagonists and beta-blockers]. -PG - 152-8 -FAU - Hasegawa, Junichi -AU - Hasegawa J -AD - Division of Pharmacotherapeutics, Department of Pathophysiological Science, - Faculty of Medicine, Tottori University. -LA - jpn -PT - Journal Article -PT - Review -PL - Japan -TA - Nihon Rinsho -JT - Nihon rinsho. Japanese journal of clinical medicine -JID - 0420546 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Calcium Channel Blockers) -SB - IM -MH - Adrenergic beta-Antagonists/*adverse effects -MH - Arrhythmias, Cardiac/*chemically induced -MH - Calcium Channel Blockers/*adverse effects -MH - Citrus paradisi -MH - Coronary Vasospasm/chemically induced -MH - Depression/chemically induced -MH - Depression, Chemical -MH - Drug Interactions -MH - Food-Drug Interactions -MH - Heart Rate/drug effects -MH - Humans -MH - Lipid Metabolism Disorders/chemically induced -MH - Myocardial Contraction/drug effects -MH - Sympathetic Nervous System/physiopathology -RF - 15 -EDAT- 2007/12/13 09:00 -MHDA- 2008/02/28 09:00 -CRDT- 2007/12/13 09:00 -PHST- 2007/12/13 09:00 [pubmed] -PHST- 2008/02/28 09:00 [medline] -PHST- 2007/12/13 09:00 [entrez] -PST - ppublish -SO - Nihon Rinsho. 2007 Oct 28;65 Suppl 8:152-8. - -PMID- 18595441 -OWN - NLM -STAT- MEDLINE -DCOM- 20080807 -LR - 20240511 -IS - 1550-9389 (Print) -IS - 1550-9397 (Electronic) -IS - 1550-9389 (Linking) -VI - 4 -IP - 3 -DP - 2008 Jun 15 -TI - Obstructive sleep apnea and cardiovascular disease: role of the metabolic - syndrome and its components. -PG - 261-72 -AB - Although obstructive sleep apnea and cardiovascular disease have common risk - factors, epidemiologic studies show that sleep apnea increases risks for - cardiovascular disease independently of individuals' demographic characteristics - (i.e., age, sex, and race) or risk markers (i.e., smoking, alcohol, obesity, - diabetes, dyslipidemia, atrial fibrillation, and hypertension). Individuals with - severe sleep apnea are at increased risk for coronary artery disease, congestive - heart failure, and stroke. The underlying mechanisms explaining associations - between obstructive sleep apnea and cardiovascular disease are not entirely - delineated. Several intermediary mechanisms might be involved including sustained - sympathetic activation, intrathoracic pressure changes, and oxidative stress. - Other abnormalities such as disorders in coagulation factors, endothelial damage, - platelet activation, and increased inflammatory mediators might also play a role - in the pathogenesis of cardiovascular disease. Linkage between obstructive sleep - apnea and cardiovascular disease is corroborated by evidence that treatment of - sleep apnea with continuous positive airway pressure reduces systolic blood - pressure, improves left ventricular systolic function, and diminishes platelet - activation. Several systematic studies are necessary to explicate complex - associations between sleep apnea and cardiovascular disease, which may be - compounded by the involvement of diseases comprising the metabolic syndrome - (i.e., central obesity, hypertension, diabetes, and dyslipidemia). Large-scale, - population-based studies testing causal models linking among sleep apnea, - cardiovascular morbidity, and metabolic syndrome are needed. -FAU - Jean-Louis, Girardin -AU - Jean-Louis G -AD - Brooklyn Center for Health Disparities, SUNY Downstate Medical Center Brooklyn, - NY 11203-2098, USA. gjean-louis@downstate.edu -FAU - Zizi, Ferdinand -AU - Zizi F -FAU - Clark, Luther T -AU - Clark LT -FAU - Brown, Clinton D -AU - Brown CD -FAU - McFarlane, Samy I -AU - McFarlane SI -LA - eng -GR - R24 MD001090/MD/NIMHD NIH HHS/United States -GR - R25 HL085042/HL/NHLBI NIH HHS/United States -GR - 1R24MD001090/MD/NIMHD NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - J Clin Sleep Med -JT - Journal of clinical sleep medicine : JCSM : official publication of the American - Academy of Sleep Medicine -JID - 101231977 -SB - IM -MH - Algorithms -MH - Cardiovascular Diseases/diagnosis/*epidemiology -MH - Demography -MH - Disease Progression -MH - Dyslipidemias/diagnosis/epidemiology -MH - Humans -MH - Metabolic Syndrome/*epidemiology/*physiopathology -MH - Obesity/epidemiology -MH - Prevalence -MH - Sleep Apnea, Obstructive/diagnosis/*epidemiology -PMC - PMC2546461 -EDAT- 2008/07/04 09:00 -MHDA- 2008/08/08 09:00 -PMCR- 2008/12/15 -CRDT- 2008/07/04 09:00 -PHST- 2008/07/04 09:00 [pubmed] -PHST- 2008/08/08 09:00 [medline] -PHST- 2008/07/04 09:00 [entrez] -PHST- 2008/12/15 00:00 [pmc-release] -PST - ppublish -SO - J Clin Sleep Med. 2008 Jun 15;4(3):261-72. - -PMID- 19463023 -OWN - NLM -STAT- MEDLINE -DCOM- 20090818 -LR - 20181023 -IS - 1175-3277 (Print) -IS - 1175-3277 (Linking) -VI - 9 -IP - 3 -DP - 2009 -TI - Cocaine cardiotoxicity: a review of the pathophysiology, pathology, and treatment - options. -PG - 177-96 -LID - 10.2165/00129784-200909030-00005 [doi] -AB - Cocaine is a powerful stimulant that gives users a temporary sense of euphoria, - mental alertness, talkativeness, and a decreased need for food and sleep. Cocaine - intoxication is the most frequent cause of drug-related death reported by medical - examiners in the US, and these events are most often related to the - cardiovascular manifestations of the drug. Once playing a vital role in medicine - as a local anesthetic, decades of research have established that cocaine has the - ability to cause irreversible structural damage to the heart, greatly accelerate - cardiovascular disease, and initiate sudden cardiac death. Although pathologic - findings are often reported in the literature, few images are available to - support these findings, and reviews of cocaine cardiopathology are rare. We - describe the major pathologic findings linked to cocaine abuse in earlier - research, their underlying mechanisms, and the treatment approaches currently - being used in this patient population. A MEDLINE search was conducted to identify - all English language articles from January 2000 to June 2008 with the subject - headings and key words 'cocaine', 'heart', 'toxicity', and 'cardiotoxicity'. - Epidemiologic, laboratory, and clinical studies on the pathology, - pathophysiology, and pharmacology of the effects of cocaine on the heart were - reviewed, along with relevant treatment options. Reference lists were used to - identify earlier studies on these topics, and related articles from Google - Scholar were also included. There is an established connection between cocaine - use and myocardial infarction (MI), arrhythmia, heart failure, and sudden cardiac - death. Numerous mechanisms have been postulated to explain how cocaine - contributes to these conditions. Among these, cocaine may lead to MI by causing - coronary artery vasoconstriction and accelerated atherosclerosis, and by - initiating thrombus formation. Cocaine has also been shown to block K+ channels, - increase L-type Ca2+ channel current, and inhibit Na+ influx during - depolarization, all possible causes for arrhythmia. Additionally, cocaine use has - been associated with left ventricular hypertrophy, myocarditis, and dilated - cardiomyopathy, which can lead to heart failure if drug use is continued. Certain - diagnostic tools, including ECG and serial cardiac markers, are not as accurate - in identifying MI in cocaine users experiencing chest pain. As a result, - clinicians should be suspicious of cocaine use in their differential diagnosis of - chest pain, especially in the younger male population, and proceed more - cautiously when use is suspected. Treatment for cocaine-related cardiovascular - disease is in many ways similar to treatment for traditional cardiovascular - disease. However use of beta-receptor antagonists and class Ia and III - anti-arrhythmics is strongly discouraged if the patient is likely to continue - cocaine use, because of documented adverse effects. The medical community is in - urgent need of a pharmacologic adjunct to cocaine-dependence treatment that can - deter relapse and reduce the risks associated with cardiovascular disease in - these patients. -FAU - Phillips, Katharine -AU - Phillips K -AD - Department of Pathology, Toronto General Hospital/University Health Network, - Toronto, Ontario, Canada. -FAU - Luk, Adriana -AU - Luk A -FAU - Soor, Gursharan S -AU - Soor GS -FAU - Abraham, Jonathan R -AU - Abraham JR -FAU - Leong, Shaun -AU - Leong S -FAU - Butany, Jagdish -AU - Butany J -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Am J Cardiovasc Drugs -JT - American journal of cardiovascular drugs : drugs, devices, and other - interventions -JID - 100967755 -RN - 0 (Cardiovascular Agents) -RN - I5Y540LHVR (Cocaine) -SB - IM -MH - Arrhythmias, Cardiac/chemically induced/drug therapy -MH - Cardiovascular Agents/*therapeutic use -MH - Cardiovascular Diseases/*chemically induced/pathology/physiopathology -MH - Clinical Trials as Topic -MH - Cocaine/*adverse effects/analysis/pharmacology -MH - Death, Sudden, Cardiac/etiology/prevention & control -MH - Heart/drug effects/physiopathology -MH - Heart Failure/chemically induced/drug therapy -MH - Humans -MH - Myocardial Infarction/chemically induced/drug therapy -MH - Myocardium/pathology -MH - Practice Guidelines as Topic -RF - 189 -EDAT- 2009/05/26 09:00 -MHDA- 2009/08/19 09:00 -CRDT- 2009/05/26 09:00 -PHST- 2009/05/26 09:00 [entrez] -PHST- 2009/05/26 09:00 [pubmed] -PHST- 2009/08/19 09:00 [medline] -AID - 5 [pii] -AID - 10.2165/00129784-200909030-00005 [doi] -PST - ppublish -SO - Am J Cardiovasc Drugs. 2009;9(3):177-96. doi: 10.2165/00129784-200909030-00005. - -PMID- 18549922 -OWN - NLM -STAT- MEDLINE -DCOM- 20080703 -LR - 20181201 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 51 -IP - 24 -DP - 2008 Jun 17 -TI - The year in interventional cardiology. -PG - 2355-69 -LID - 10.1016/j.jacc.2008.03.021 [doi] -FAU - Dixon, Simon R -AU - Dixon SR -AD - Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, - USA. sdixon@beaumont.edu -FAU - Grines, Cindy L -AU - Grines CL -FAU - O'Neill, William W -AU - O'Neill WW -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Platelet Aggregation Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Acute Coronary Syndrome/drug therapy/therapy -MH - American Heart Association -MH - *Angioplasty, Balloon, Coronary -MH - Clopidogrel -MH - Coronary Restenosis/therapy -MH - Drug-Eluting Stents -MH - Humans -MH - Myocardial Infarction/drug therapy/*therapy -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Ticlopidine/analogs & derivatives/therapeutic use -MH - United States -RF - 166 -EDAT- 2008/06/14 09:00 -MHDA- 2008/07/04 09:00 -CRDT- 2008/06/14 09:00 -PHST- 2008/01/24 00:00 [received] -PHST- 2008/03/17 00:00 [revised] -PHST- 2008/03/18 00:00 [accepted] -PHST- 2008/06/14 09:00 [pubmed] -PHST- 2008/07/04 09:00 [medline] -PHST- 2008/06/14 09:00 [entrez] -AID - S0735-1097(08)01130-3 [pii] -AID - 10.1016/j.jacc.2008.03.021 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2008 Jun 17;51(24):2355-69. doi: 10.1016/j.jacc.2008.03.021. - -PMID- 16595568 -OWN - NLM -STAT- MEDLINE -DCOM- 20060731 -LR - 20131121 -IS - 1060-0280 (Print) -IS - 1060-0280 (Linking) -VI - 40 -IP - 5 -DP - 2006 May -TI - Cangrelor for treatment of coronary thrombosis. -PG - 925-30 -AB - OBJECTIVE: To review and assess available literature on the chemistry, - pharmacology, pharmacodynamics, pharmacokinetics, clinical studies, adverse - events, drug interactions, special populations, and dosing and administration for - cangrelor, a product in late stage Phase II clinical trials. DATA SOURCES: A - literature search of MEDLINE (1966-March 2006), International Pharmaceutical - Abstracts (1970-February 2006), and Cochrane database (first quarter 2006) was - conducted using key terms of cangrelor, AR-C69931MX, and P2Y12 receptor - antagonist. Bibliographies of relevant articles were reviewed for additional - references. The Medicines Company Web site was reviewed, and a company - representative was contacted. STUDY SELECTION AND DATA EXTRACTION: Available - English-language literature, including abstracts, preclinical studies, clinical - trials, and review articles, was reviewed. DATA SYNTHESIS: Cangrelor is a P2Y12 - antagonist under development for treatment of acute coronary syndrome. Cangrelor - has been studied as an intravenous infusion in doses of 2 or 4 microg/kg/min. It - inhibits platelet aggregation with rapid onset and offset and does not require - metabolism for therapeutic activity. Published Phase II trials have demonstrated - safety and inhibition of platelet aggregation. CONCLUSIONS: Cangrelor is a - promising investigational medication for inhibition of platelet aggregation in - acute arterial coronary events. Phase II trials have shown safety and a greater - inhibition of platelet aggregation over clopidogrel. Phase III trials will - provide more definitive information on clinical efficacy and safety. Until then, - the role of cangrelor is uncertain. -FAU - Fugate, Susan E -AU - Fugate SE -AD - College of Pharmacy, University of Oklahoma, Oklahoma City, OK 73190-5040, USA. - susan-fugate@ouhsc.edu -FAU - Cudd, Laura A -AU - Cudd LA -LA - eng -PT - Journal Article -PT - Review -DEP - 20060404 -PL - United States -TA - Ann Pharmacother -JT - The Annals of pharmacotherapy -JID - 9203131 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Purinergic P2 Receptor Antagonists) -RN - 415SHH325A (Adenosine Monophosphate) -RN - 6AQ1Y404U7 (cangrelor) -SB - IM -MH - Adenosine Monophosphate/adverse effects/*analogs & - derivatives/pharmacology/therapeutic use -MH - Animals -MH - Clinical Trials as Topic -MH - Coronary Thrombosis/*drug therapy -MH - Drug Interactions -MH - Humans -MH - Platelet Aggregation Inhibitors/adverse effects/pharmacology/*therapeutic use -MH - *Purinergic P2 Receptor Antagonists -RF - 24 -EDAT- 2006/04/06 09:00 -MHDA- 2006/08/01 09:00 -CRDT- 2006/04/06 09:00 -PHST- 2006/04/06 09:00 [pubmed] -PHST- 2006/08/01 09:00 [medline] -PHST- 2006/04/06 09:00 [entrez] -AID - aph.1G120 [pii] -AID - 10.1345/aph.1G120 [doi] -PST - ppublish -SO - Ann Pharmacother. 2006 May;40(5):925-30. doi: 10.1345/aph.1G120. Epub 2006 Apr 4. - -PMID- 22130965 -OWN - NLM -STAT- MEDLINE -DCOM- 20120529 -LR - 20240130 -IS - 1532-6551 (Electronic) -IS - 1071-3581 (Linking) -VI - 19 -IP - 1 -DP - 2012 Feb -TI - Use of cardiac radionuclide imaging to identify patients at risk for arrhythmic - sudden cardiac death. -PG - 142-52; quiz 153-7 -LID - 10.1007/s12350-011-9482-9 [doi] -AB - Sudden cardiac death (SCD) accounts for about ½ of all cardiovascular deaths, in - most cases the result of a lethal ventricular arrhythmia. Patients considered at - risk are often treated with an implantable cardiac defibrillator (ICD), but - current criteria for device use, based largely on left ventricular ejection - fraction (LVEF), leads to many patients receiving ICDs that they do not use, and - many others not receiving ICDs but who suffer SCD. Thus, better methods of - identifying patients at risk for SCD are needed, and radionuclide imaging offers - much potential. Recent work has focused on imaging of cardiac autonomic - innervation. (123)I-mIBG, a norepinephrine analog, is the tracer most studied, - and a variety of positron emission tomographic tracers are also under - investigation. Radionuclide autonomic imaging may identify at-risk patients with - ischemic coronary artery disease, particularly following myocardial infarction - and in the setting of hibernating myocardium. Most studies have been done in the - setting of congestive heart failure (CHF), with a recent large multicenter study - of patients with advanced disease, typically at high risk of SCD, showing that - (123)I-mIBG can identify a low risk subgroup with an extremely low incidence of - lethal ventricular arrhythmias and cardiac death, therefore, perhaps not - requiring an ICD. Cardiac neuronal imaging has been shown to be better predictive - of lethal arrhythmias/cardiac death than LVEF and New York Heart Association - class, as well as various ECG parameters. Autonomic imaging will likely play an - important role in the advancement of cardiac molecular imaging. -FAU - Kelesidis, Iosif -AU - Kelesidis I -AD - Department of Nuclear Medicine, Montefiore Medical Center, Albert Einstein - College of Medicine, 111 East-210th Street, Bronx, NY 10467-2490, USA. -FAU - Travin, Mark I -AU - Travin MI -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Nucl Cardiol -JT - Journal of nuclear cardiology : official publication of the American Society of - Nuclear Cardiology -JID - 9423534 -RN - 0 (Radiopharmaceuticals) -RN - 35MRW7B4AD (3-Iodobenzylguanidine) -SB - IM -MH - *3-Iodobenzylguanidine -MH - Death, Sudden, Cardiac/*epidemiology/*prevention & control -MH - Humans -MH - Radionuclide Imaging/*methods -MH - Radiopharmaceuticals -MH - Ventricular Dysfunction, Left/*diagnostic imaging/*mortality/prevention & control -EDAT- 2011/12/02 06:00 -MHDA- 2012/05/30 06:00 -CRDT- 2011/12/02 06:00 -PHST- 2011/12/02 06:00 [entrez] -PHST- 2011/12/02 06:00 [pubmed] -PHST- 2012/05/30 06:00 [medline] -AID - S1071-3581(23)03069-6 [pii] -AID - 10.1007/s12350-011-9482-9 [doi] -PST - ppublish -SO - J Nucl Cardiol. 2012 Feb;19(1):142-52; quiz 153-7. doi: - 10.1007/s12350-011-9482-9. - -PMID- 18813212 -OWN - NLM -STAT- MEDLINE -DCOM- 20090123 -LR - 20111117 -IS - 1743-4300 (Electronic) -IS - 1743-4297 (Linking) -VI - 5 -IP - 11 -DP - 2008 Nov -TI - Interplay between impaired calcium regulation and insulin signaling abnormalities - in diabetic cardiomyopathy. -PG - 715-24 -LID - 10.1038/ncpcardio1347 [doi] -AB - According to the International Diabetes Federation the number of people between - the ages of 20 and 79 years diagnosed with diabetes mellitus is projected to - reach 380 million worldwide by 2025. Cardiovascular disease, including heart - failure, is the major cause of death in patients with diabetes. A contributing - factor to heart failure in such patients is the development of diabetic - cardiomyopathy--a clinical myocardial condition distinguished by ventricular - dysfunction that can present independently of other risk factors such as - hypertension or coronary artery disease. This disorder has been associated with - both type 1 and type 2 diabetes, and is characterized by early-onset diastolic - dysfunction and late-onset systolic dysfunction. The development of diabetic - cardiomyopathy and the cellular and molecular perturbations associated with the - pathology are complex and multifactorial. Hallmark mechanisms include - abnormalities in regulation of calcium homeostasis, and associated abnormal - ventricular excitation-contraction coupling, metabolic disturbances, and - alterations in insulin signaling. An emerging concept is that disruptions in - calcium homeostasis might be linked to diminished insulin responsiveness. An - understanding of the cellular effect of these abnormalities on cardiomyocytes - should be useful in predicting the maladaptive cardiac structural and functional - consequences of diabetes. -FAU - Lebeche, Djamel -AU - Lebeche D -AD - Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY - 10029, USA. djamel.lebeche@mssm.edu -FAU - Davidoff, Amy J -AU - Davidoff AJ -FAU - Hajjar, Roger J -AU - Hajjar RJ -LA - eng -GR - HL057263/HL/NHLBI NIH HHS/United States -GR - HL071763/HL/NHLBI NIH HHS/United States -GR - HL078731/HL/NHLBI NIH HHS/United States -GR - HL080498/HL/NHLBI NIH HHS/United States -GR - HL083156/HL/NHLBI NIH HHS/United States -GR - HL66895/HL/NHLBI NIH HHS/United States -GR - K01 HL076659/HL/NHLBI NIH HHS/United States -GR - R01 HL078691/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080923 -PL - England -TA - Nat Clin Pract Cardiovasc Med -JT - Nature clinical practice. Cardiovascular medicine -JID - 101226507 -RN - 0 (Blood Glucose) -RN - 0 (Insulin) -SB - IM -MH - Adult -MH - Aged -MH - Blood Glucose/metabolism -MH - *Calcium Signaling -MH - Cardiomyopathies/*metabolism/pathology/physiopathology/therapy -MH - Diabetes Complications/*metabolism/pathology/physiopathology/therapy -MH - Humans -MH - Insulin/*metabolism -MH - Insulin Resistance -MH - Middle Aged -MH - Myocardial Contraction -MH - Myocardium/*metabolism/pathology -MH - Ventricular Function -MH - Young Adult -RF - 72 -EDAT- 2008/09/25 09:00 -MHDA- 2009/01/24 09:00 -CRDT- 2008/09/25 09:00 -PHST- 2008/11/30 00:00 [received] -PHST- 2008/07/30 00:00 [accepted] -PHST- 2008/09/25 09:00 [pubmed] -PHST- 2009/01/24 09:00 [medline] -PHST- 2008/09/25 09:00 [entrez] -AID - ncpcardio1347 [pii] -AID - 10.1038/ncpcardio1347 [doi] -PST - ppublish -SO - Nat Clin Pract Cardiovasc Med. 2008 Nov;5(11):715-24. doi: 10.1038/ncpcardio1347. - Epub 2008 Sep 23. - -PMID- 18222351 -OWN - NLM -STAT- MEDLINE -DCOM- 20080226 -LR - 20080128 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 51 -IP - 4 -DP - 2008 Jan 29 -TI - Experimental and clinical basis for the use of statins in patients with ischemic - and nonischemic cardiomyopathy. -PG - 415-26 -LID - 10.1016/j.jacc.2007.10.009 [doi] -AB - Over the past 2 decades our understanding of the pathologic mechanisms that lead - to heart failure (HF) has evolved from simplistic hemodynamic models to more - complex models that have implicated neurohormonal activation and adverse cardiac - remodeling as important mechanisms of disease progression. - 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) have become - a standard part of the armamentarium in the prevention and treatment of coronary - artery disease. Apart from their lipid-lowering capabilities, statins seem to - have non-lipid-lowering effects that impact neurohormonal activation and cardiac - remodeling. This review will examine the potential benefits of statins in HF - patients with ischemic and nonischemic cardiomyopathy as well as potential - concerns regarding the use of statins in these patients. -FAU - Ramasubbu, Kumudha -AU - Ramasubbu K -AD - Winters Center for Heart Failure Research, Department of Medicine, Baylor College - of Medicine and The Texas Heart Institute at St. Luke's Episcopal Hospital, - Houston, Texas 77030, USA. -FAU - Estep, Jerry -AU - Estep J -FAU - White, Donna L -AU - White DL -FAU - Deswal, Anita -AU - Deswal A -FAU - Mann, Douglas L -AU - Mann DL -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Antioxidants) -RN - 0 (Autonomic Agents) -RN - 0 (Cytokines) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Lipoproteins) -RN - 0 (Neurotransmitter Agents) -RN - 0 (Selenoproteins) -RN - 1339-63-5 (Ubiquinone) -SB - IM -MH - Anti-Arrhythmia Agents/therapeutic use -MH - Anti-Inflammatory Agents/therapeutic use -MH - Antioxidants/therapeutic use -MH - Autonomic Agents/therapeutic use -MH - Cardiomyopathies/complications/*drug therapy/metabolism/pathology -MH - Cytokines/drug effects/metabolism -MH - Drug Evaluation -MH - Endothelium, Vascular/drug effects -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Hypertrophy/drug therapy/pathology -MH - Lipoproteins/drug effects/metabolism -MH - Myocardial Ischemia/complications/*drug therapy/metabolism/pathology -MH - Myocardium/pathology -MH - Neovascularization, Pathologic/drug therapy -MH - Neurotransmitter Agents/metabolism -MH - Selenoproteins/drug effects/metabolism -MH - Treatment Outcome -MH - Ubiquinone/drug effects/metabolism -MH - Ventricular Remodeling/drug effects -RF - 103 -EDAT- 2008/01/29 09:00 -MHDA- 2008/02/27 09:00 -CRDT- 2008/01/29 09:00 -PHST- 2007/07/02 00:00 [received] -PHST- 2007/10/01 00:00 [revised] -PHST- 2007/10/02 00:00 [accepted] -PHST- 2008/01/29 09:00 [pubmed] -PHST- 2008/02/27 09:00 [medline] -PHST- 2008/01/29 09:00 [entrez] -AID - S0735-1097(07)03348-7 [pii] -AID - 10.1016/j.jacc.2007.10.009 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2008 Jan 29;51(4):415-26. doi: 10.1016/j.jacc.2007.10.009. - -PMID- 23200092 -OWN - NLM -STAT- MEDLINE -DCOM- 20130221 -LR - 20141120 -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 29 -IP - 1 -DP - 2013 Jan -TI - From genome-wide association studies to functional genomics: new insights into - cardiovascular disease. -PG - 23-9 -LID - S0828-282X(12)01247-0 [pii] -LID - 10.1016/j.cjca.2012.08.017 [doi] -AB - Genome-wide association studies (GWASs) for coronary artery disease (CAD) have - identified more than 30 variants robustly associated with CAD risk. The majority - are not associated with conventional risk factors but highlight novel pathways, - including cellular proliferation. Although some risk variants are nonsynonymous - coding variants resulting in an amino acid change in the encoded protein, the - majority are in noncoding regions of the genome and may encompass multiple - signals of variable effect. The use of genetic data for development of new - therapies requires the identification of causative genetic variants and - elucidation of the molecular mechanisms by which they predispose to CAD. The - computational and laboratory approaches for the interpretation of GWAS data are - discussed with a particular focus on noncoding variants, including the study of - regulatory elements, the evaluation of nonsynonymous coding variants, and - expression quantitative trait locus analysis for the integration of GWAS data - with genome-wide messenger RNA expression data. -CI - Copyright © 2013 Canadian Cardiovascular Society. Published by Elsevier Inc. All - rights reserved. -FAU - McPherson, Ruth -AU - McPherson R -AD - Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin St-H4203, - Ottawa, Canada. rmcpherson@ottawaheart.ca -LA - eng -GR - MOP-2380941/Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121128 -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -RN - 0 (RNA, Messenger) -SB - IM -MH - Cardiovascular Diseases/*epidemiology/*genetics -MH - *Genetic Predisposition to Disease -MH - Genome-Wide Association Study/*methods -MH - Genotype -MH - Global Health -MH - Humans -MH - Morbidity -MH - *Polymorphism, Single Nucleotide -MH - RNA, Messenger/*genetics -MH - Risk Factors -EDAT- 2012/12/04 06:00 -MHDA- 2013/02/22 06:00 -CRDT- 2012/12/04 06:00 -PHST- 2012/07/11 00:00 [received] -PHST- 2012/08/21 00:00 [revised] -PHST- 2012/08/21 00:00 [accepted] -PHST- 2012/12/04 06:00 [entrez] -PHST- 2012/12/04 06:00 [pubmed] -PHST- 2013/02/22 06:00 [medline] -AID - S0828-282X(12)01247-0 [pii] -AID - 10.1016/j.cjca.2012.08.017 [doi] -PST - ppublish -SO - Can J Cardiol. 2013 Jan;29(1):23-9. doi: 10.1016/j.cjca.2012.08.017. Epub 2012 - Nov 28. - -PMID- 19815121 -OWN - NLM -STAT- MEDLINE -DCOM- 20091027 -LR - 20220330 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 54 -IP - 16 -DP - 2009 Oct 13 -TI - Nebivolol: the somewhat-different beta-adrenergic receptor blocker. -PG - 1491-9 -LID - 10.1016/j.jacc.2009.05.066 [doi] -AB - Although its clinical use in Europe dates almost 10 years, nebivolol is a - beta-blocker that has been only recently introduced in the U.S. market. Like - carvedilol, nebivolol belongs to the third generation of beta-blockers, which - possess direct vasodilator properties in addition to their adrenergic blocking - characteristics. Nebivolol has the highest beta(1)-receptor affinity among - beta-blockers and, most interestingly, it substantially improves endothelial - dysfunction via its strong stimulatory effects on the activity of the endothelial - nitric oxide synthase and via its antioxidative properties. Because impaired - endothelial activity is attributed a major causal role in the pathophysiology of - hypertension, coronary artery disease, and congestive heart failure, the - endothelium-agonistic properties of nebivolol suggest that this drug might - provide additional benefit beyond beta-receptor blockade. Although lesser - beta-blocker-related side effects have been reported in patients with chronic - obstructive pulmonary disease or impotence taking nebivolol, side effects and - contraindications overlap those of other beta-blockers. Clinically, this compound - has been proven to have antihypertensive and anti-ischemic effects as well as - beneficial effects on hemodynamics and prognosis in patients with chronic - congestive heart failure. Further studies are now necessary to compare the - benefit of nebivolol with that of other drugs in the same class and, most - importantly, its prognostic impact in patients with hypertension. -FAU - Münzel, Thomas -AU - Münzel T -AD - II Medizinische Klinik für Kardiologie/Angiologie, Langenbeckstrasse 1, Mainz, - Germany. tmuenzel@uni-mainz.de -FAU - Gori, Tommaso -AU - Gori T -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Benzopyrans) -RN - 0 (Ethanolamines) -RN - 030Y90569U (Nebivolol) -RN - 31C4KY9ESH (Nitric Oxide) -SB - IM -MH - *Adrenergic beta-Antagonists/chemistry/pharmacokinetics/therapeutic use -MH - Animals -MH - *Benzopyrans/chemistry/pharmacokinetics/therapeutic use -MH - Cardiovascular Diseases/*drug therapy/metabolism/physiopathology -MH - Endothelium, Vascular/drug effects/metabolism/physiopathology -MH - *Ethanolamines/chemistry/pharmacokinetics/therapeutic use -MH - Hemodynamics/drug effects/physiology -MH - Humans -MH - Nebivolol -MH - Nitric Oxide/metabolism -MH - Oxidative Stress/*drug effects -RF - 79 -EDAT- 2009/10/10 06:00 -MHDA- 2009/10/29 06:00 -CRDT- 2009/10/10 06:00 -PHST- 2009/04/14 00:00 [received] -PHST- 2009/05/06 00:00 [accepted] -PHST- 2009/10/10 06:00 [entrez] -PHST- 2009/10/10 06:00 [pubmed] -PHST- 2009/10/29 06:00 [medline] -AID - S0735-1097(09)02431-0 [pii] -AID - 10.1016/j.jacc.2009.05.066 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2009 Oct 13;54(16):1491-9. doi: 10.1016/j.jacc.2009.05.066. - -PMID- 18092947 -OWN - NLM -STAT- MEDLINE -DCOM- 20080212 -LR - 20250529 -IS - 1470-8728 (Electronic) -IS - 0264-6021 (Linking) -VI - 409 -IP - 2 -DP - 2008 Jan 15 -TI - The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory - factor in vascular disease. -PG - 349-55 -AB - Scavenger receptors are membrane glycoproteins that bind diverse ligands - including lipid particles, phospholipids, apoptotic cells and pathogens. LOX-1 - (lectin-like oxidized low-density lipoprotein receptor-1) is increasingly linked - to atherosclerotic plaque formation. Transgenic mouse models for LOX-1 - overexpression or gene knockout suggests that LOX-1 contributes to - atherosclerotic plaque formation and progression. LOX-1 activation by oxidized - LDL (low-density lipoprotein) binding stimulates intracellular signalling, gene - expression and production of superoxide radicals. A key question is the role of - leucocyte LOX-1 in pro-atherogenic lipid particle trafficking, accumulation and - signalling leading to differentiation into foam cells, necrosis and plaque - development. LOX-1 expression is elevated within vascular lesions and a serum - soluble LOX-1 fragment appears diagnostic of patients with acute coronary - syndromes. LOX-1 is increasingly viewed as a vascular disease biomarker and a - potential therapeutic target in heart attack and stroke prevention. -FAU - Dunn, Sarah -AU - Dunn S -AD - Endothelial Cell Biology Unit, Leeds Institute of Genetics, Health and - Therapeutics, University of Leeds, Clarendon Way, Leeds LS2 9JT, UK. -FAU - Vohra, Ravinder S -AU - Vohra RS -FAU - Murphy, Jane E -AU - Murphy JE -FAU - Homer-Vanniasinkam, Shervanthi -AU - Homer-Vanniasinkam S -FAU - Walker, John H -AU - Walker JH -FAU - Ponnambalam, Sreenivasan -AU - Ponnambalam S -LA - eng -GR - PG/06/141/21879/BHF_/British Heart Foundation/United Kingdom -GR - WT_/Wellcome Trust/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Biochem J -JT - The Biochemical journal -JID - 2984726R -RN - 0 (Biomarkers) -RN - 0 (Ligands) -RN - 0 (Lipoproteins, LDL) -RN - 0 (Scavenger Receptors, Class E) -SB - IM -MH - Animals -MH - Atherosclerosis/*metabolism -MH - Biomarkers -MH - Humans -MH - Inflammation/metabolism -MH - Ligands -MH - Lipoproteins, LDL/metabolism -MH - Mice -MH - Models, Animal -MH - Protein Transport -MH - Scavenger Receptors, Class E/chemistry/genetics/*metabolism -MH - Signal Transduction -RF - 63 -EDAT- 2007/12/21 09:00 -MHDA- 2008/02/13 09:00 -CRDT- 2007/12/21 09:00 -PHST- 2007/12/21 09:00 [pubmed] -PHST- 2008/02/13 09:00 [medline] -PHST- 2007/12/21 09:00 [entrez] -AID - BJ20071196 [pii] -AID - 10.1042/BJ20071196 [doi] -PST - ppublish -SO - Biochem J. 2008 Jan 15;409(2):349-55. doi: 10.1042/BJ20071196. - -PMID- 24096325 -OWN - NLM -STAT- MEDLINE -DCOM- 20140910 -LR - 20211021 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Print) -IS - 0195-668X (Linking) -VI - 35 -IP - 3 -DP - 2014 Jan -TI - Reperfusion therapy of acute ischaemic stroke and acute myocardial infarction: - similarities and differences. -PG - 147-55 -LID - 10.1093/eurheartj/eht409 [doi] -AB - The evolution of reperfusion therapy in acute myocardial infarction and acute - ischaemic stroke has many similarities: thrombolysis is superior to placebo, - intra-arterial thrombolysis is not superior to intravenous (i.v.), facilitated - intervention is of questionable value, and direct mechanical recanalization - without thrombolysis is proven (myocardial infarction) or promising (stroke) to - be superior to thrombolysis-but only when started with no or minimal delay. - However, there are also substantial differences. Direct catheter-based - thrombectomy in acute ischaemic stroke is more difficult than primary angioplasty - (in ST-elevation myocardial infarction [STEMI]) in many ways: complex - pre-intervention diagnostic workup, shorter time window for clinically effective - reperfusion, need for an emergent multidisciplinary approach from the first - medical contact, vessel tortuosity, vessel fragility, no evidence available about - dosage and combination of peri-procedural antithrombotic drugs, risk of - intracranial bleeding, unclear respective roles of thrombolysis and mechanical - intervention, lower number of suitable patients, and thus longer learning curves - of the staff. Thus, starting acute stroke interventional programme requires a lot - of learning, discipline, and humility. Randomized trials comparing different - reperfusion strategies provided similar results in acute ischaemic stroke as in - STEMI. Thus, it might be expected that also a future randomized trial comparing - direct (primary) catheter-based thrombectomy vs. i.v. thrombolysis could show - superiority of the mechanical intervention if it would be initiated without - delay. Such randomized trial is needed to define the role of mechanical - intervention alone in acute stroke treatment. -FAU - Widimsky, Petr -AU - Widimsky P -AD - Cardiocenter, Third Faculty of Medicine, Charles University Prague, Ruska 87, 100 - 00 Prague 10, Czech Republic. -FAU - Coram, Rita -AU - Coram R -FAU - Abou-Chebl, Alex -AU - Abou-Chebl A -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131003 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (Fibrinolytic Agents) -SB - IM -MH - Acute Disease -MH - Clinical Trials as Topic -MH - Combined Modality Therapy -MH - Fibrinolytic Agents/therapeutic use -MH - Humans -MH - Infusions, Intravenous -MH - Myocardial Infarction/*therapy -MH - Percutaneous Coronary Intervention/methods -MH - Reperfusion/*methods -MH - Stroke/*therapy -MH - Thrombectomy/methods -MH - Thrombolytic Therapy/methods -PMC - PMC3890694 -OTO - NOTNLM -OT - Acute stroke -OT - Catheter intervention -OT - Myocardial infarction -OT - Primary angioplasty -OT - Reperfusion -OT - Thrombectomy -OT - Thrombolysis -EDAT- 2013/10/08 06:00 -MHDA- 2014/09/11 06:00 -PMCR- 2013/10/03 -CRDT- 2013/10/08 06:00 -PHST- 2013/10/08 06:00 [entrez] -PHST- 2013/10/08 06:00 [pubmed] -PHST- 2014/09/11 06:00 [medline] -PHST- 2013/10/03 00:00 [pmc-release] -AID - eht409 [pii] -AID - 10.1093/eurheartj/eht409 [doi] -PST - ppublish -SO - Eur Heart J. 2014 Jan;35(3):147-55. doi: 10.1093/eurheartj/eht409. Epub 2013 Oct - 3. - -PMID- 17438877 -OWN - NLM -STAT- MEDLINE -DCOM- 20070627 -LR - 20151119 -IS - 0048-7848 (Print) -IS - 0048-7848 (Linking) -VI - 110 -IP - 4 -DP - 2006 Oct-Dec -TI - [Vasospastic angina]. -PG - 791-6 -AB - Vasospastic angina is associated with ventricular arrhythmias, acute myocardial - infarction and sudden arrhythmic death. The main ischemic mechanism in - vasospastic angina is coronary spasm. Because the demonstration of spontaneous - coronary spasm is difficult, a number of methods which can provoke spasm in - susceptible patients were imagined. The most used clinical methods of diagnostic - provocation testing were analyzed. -FAU - Mereuţa, A -AU - Mereuţa A -AD - Institutul de Boli Cardiovasculare "Prof. Dr. C.C. Iliescu", Bucureşti. -LA - rum -PT - English Abstract -PT - Journal Article -PT - Review -TT - Angina vasospastica. Teste de provocare a spasmului coronarian. -PL - Romania -TA - Rev Med Chir Soc Med Nat Iasi -JT - Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi -JID - 0413735 -RN - 0 (Cholinergic Agents) -RN - 0 (Oxytocics) -RN - N9YNS0M02X (Acetylcholine) -RN - WH41D8433D (Ergonovine) -SB - IM -MH - Acetylcholine -MH - Angina Pectoris, Variant/chemically induced/*diagnosis/etiology -MH - Arrhythmias, Cardiac/complications -MH - Cholinergic Agents -MH - Coronary Vasospasm/diagnosis -MH - Electrocardiography -MH - Ergonovine -MH - Humans -MH - Hyperventilation -MH - Myocardial Infarction/complications -MH - Oxytocics -MH - Physical Exertion -MH - Sensitivity and Specificity -RF - 26 -EDAT- 2007/04/19 09:00 -MHDA- 2007/06/28 09:00 -CRDT- 2007/04/19 09:00 -PHST- 2007/04/19 09:00 [pubmed] -PHST- 2007/06/28 09:00 [medline] -PHST- 2007/04/19 09:00 [entrez] -PST - ppublish -SO - Rev Med Chir Soc Med Nat Iasi. 2006 Oct-Dec;110(4):791-6. - -PMID- 19891279 -OWN - NLM -STAT- MEDLINE -DCOM- 20091201 -LR - 20250607 -IS - 1083-4087 (Print) -IS - 1944-706X (Electronic) -IS - 1083-4087 (Linking) -VI - 14 -IP - 8 Suppl -DP - 2008 Oct -TI - Targeting low HDL-cholesterol to decrease residual cardiovascular risk in the - managed care setting. -PG - S3-28; quiz S30-1 -LID - 10.18553/jmcp.2008.14.S8-A.1 -AB - BACKGROUND: Most clinicians recognize the importance of reducing low-density - lipoprotein cholesterol (LDL-C) and, therefore, address this therapeutic need to - decrease cardiovascular disease risk. In addition to the critical role that LDL-C - plays, recent studies have shown the contribution of other lipid fractions, such - as high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG), to - overall cardiovascular health. Managed care initiatives to reduce cardiovascular - risk typically focus on highly effective statin therapies, which are primarily - LDL-C-lowering agents and have lesser TG-lowering and HDL-C-raising effects. - However, clinical and epidemiologic data illustrate the need to expand the scope - of therapies to reduce the residual cardiovascular risk associated with low HDL-C - levels and elevated TG levels, even when LDL-C is managed successfully. - OBJECTIVE: To address the value of treating beyond LDL-C level to improve patient - health outcomes and reduce health care-related costs. SUMMARY: Several large - trials and meta-analyses have investigated the effects of lipid-lowering statin - therapy and have consistently demonstrated that statin therapy significantly - reduces LDL-C levels and incidence of cardiovascular events. In spite of the - efficacy of statin therapy in these studies, statins did not eliminate - cardiovascular risk. Rather, significant residual cardiovascular risk remains - after treatment with statins, especially in high-risk patients such as those with - diabetes. Residual cardiovascular risk stems, at least partially, from low HDL-C - and elevated TG. Low HDL-C levels have been identified as a significant, - independent predictor of cardiovascular risk, and increases in HDL-C are - associated with reductions in cardiovascular events. High TG levels are a - significant risk factor for cardiovascular disease and are a marker for - atherogenic remnant lipo-proteins, such as very low-density lipoprotein - cholesterol (VLDL-C). Additionally, with elevated TG levels, a combination of - LDL-C with VLDL-C in the measure of non-HDL-C may be a better predictor of - cardiovascular risk than LDL-C alone. Recent national treatment guidelines - suggest that combination therapy may be necessary to address multiple lipid - targets (i.e., LDL-C, non-HDL-C, HDL-C, and TG); adding niacin or a fibrate to a - statin is a therapeutic option that should be considered. As monotherapy agents, - fibrates and niacin have been demonstrated to alter several lipid parameters and - reduce cardiovascular events. Niacin appears to exert the greatest beneficial - effects on the widest range of lipoprotein abnormalities, in addition to - possessing an established safety profile. Moreover, niacin/statin combination - therapy may provide greater benefits, as manifested through a correction of - atherogenic lipid abnormalities, a slowing of atherosclerosis progression in - coronary heart disease (CHD) patients, and a reduction of residual cardiovascular - risk. Pharmacoeconomic modeling studies have been used to describe the potential - effects on both cardiovascular events and health care costs by the achievement - of, or failure to achieve, combined optimal lipid values (OLVs). Achievement of - OLVs is predicted to be associated with a reduced risk of cardiovascular events, - in which greater magnitudes of risk reduction accompany the achievement of a - greater number of lipid goals. Based on patient baseline lipid values and product - labeling information, mathematical models estimate that OLVs are achieved more - frequently with extended-release niacin (niacin ER)/simvastatin combination - therapy than with other high-potency agents. These modeling estimates were - maintained in different patient groups, including those with diabetes or the - metabolic syndrome. Finally, these modeling studies estimated that a fixed-dose - niacin ER/simvastatin combination therapy would reduce direct medical costs of - CHD events more effectively than would high-dose simvastatin monotherapy. - CONCLUSION: Statins are highly effective for lowering LDL-C levels and, - consequently, cardiovascular event rates. However, statins do not eliminate - cardiovascular risk. Even in the presence of tightly controlled LDL-C levels, - evidence indicates that high TG and low HDL-C levels are independent - cardiovascular risk factors. Treating lipid parameters beyond LDL-C may require - the addition of niacin or a fibrate to statin therapy. Niacin is the most - effective agent for raising HDL-C levels, and pharmacoeconomic modeling suggests - that niacin ER/statin combination therapy may promote the cost-effective - achievement of OLVs in several at-risk patient populations. -FAU - Cziraky, Mark J -AU - Cziraky MJ -AD - HealthCore Inc., Wilmington, Delaware, USA. -FAU - Watson, Karol E -AU - Watson KE -FAU - Talbert, Robert L -AU - Talbert RL -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Manag Care Pharm -JT - Journal of managed care pharmacy : JMCP -JID - 9605854 -RN - 0 (Cholesterol, HDL) -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Hypolipidemic Agents) -RN - 0 (Triglycerides) -SB - IM -MH - Cardiovascular Diseases/*blood/*prevention & control -MH - Cholesterol, HDL/*blood -MH - Cholesterol, LDL/blood -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Hypercholesterolemia/*drug therapy -MH - Hypolipidemic Agents/therapeutic use -MH - *Managed Care Programs -MH - Risk Management -MH - Triglycerides/blood -PMC - PMC10438150 -EDAT- 2009/11/07 06:00 -MHDA- 2009/12/16 06:00 -PMCR- 2008/10/01 -CRDT- 2009/11/07 06:00 -PHST- 2009/11/07 06:00 [entrez] -PHST- 2009/11/07 06:00 [pubmed] -PHST- 2009/12/16 06:00 [medline] -PHST- 2008/10/01 00:00 [pmc-release] -AID - 10.18553/jmcp.2008.14.S8-A.1 [doi] -PST - ppublish -SO - J Manag Care Pharm. 2008 Oct;14(8 Suppl):S3-28; quiz S30-1. doi: - 10.18553/jmcp.2008.14.S8-A.1. - -PMID- 23149428 -OWN - NLM -STAT- MEDLINE -DCOM- 20130312 -LR - 20220330 -IS - 1941-7705 (Electronic) -IS - 1941-7713 (Print) -IS - 1941-7713 (Linking) -VI - 5 -IP - 6 -DP - 2012 Nov -TI - Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: a - meta-analysis of prospective studies. -PG - 819-29 -LID - 10.1161/CIRCOUTCOMES.112.967604 [doi] -AB - BACKGROUND: Vitamin D status has been linked to the risk of cardiovascular - disease (CVD). However, the optimal 25-hydroxy-vitamin D (25[OH]-vitamin D) - levels for potential cardiovascular health benefits remain unclear. METHODS AND - RESULTS: We searched MEDLINE and EMBASE from 1966 through February 2012 for - prospective studies that assessed the association of 25(OH)-vitamin D - concentrations with CVD risk. A total of 24 articles met our inclusion criteria, - from which 19 independent studies with 6123 CVD cases in 65 994 participants were - included for a meta-analysis. In a comparison of the lowest with the highest - 25(OH)-vitamin D categories, the pooled relative risk was 1.52 (95% confidence - interval, 1.30-1.77) for total CVD, 1.42 (95% confidence interval, 1.19-1.71) for - CVD mortality, 1.38 (95% confidence interval, 1.21-1.57) for coronary heart - disease, and 1.64 (95% confidence interval, 1.27-2.10) for stroke. These - associations remained strong and significant when analyses were limited to - studies that excluded participants with baseline CVD and were better controlled - for season and confounding. We used a fractional polynomial spline regression - analysis to assess the linearity of dose-response association between continuous - 25(OH)-vitamin D and CVD risk. The CVD risk increased monotonically across - decreasing 25(OH)-vitamin D below ≈60 nmol/L, with a relative risk of 1.03 (95% - confidence interval, 1.00-1.06) per 25-nmol/L decrement in 25(OH)-vitamin D. - CONCLUSIONS: This meta-analysis demonstrated a generally linear, inverse - association between circulating 25(OH)-vitamin D ranging from 20 to 60 nmol/L and - risk of CVD. Further research is needed to clarify the association of - 25(OH)-vitamin D higher than 60 nmol/L with CVD risk and assess causality of the - observed associations. -FAU - Wang, Lu -AU - Wang L -AD - Brigham and Women’s Hospital, Boston, MA 02215, USA. luwang@rics.bwh.harvard.edu -FAU - Song, Yiqing -AU - Song Y -FAU - Manson, Joann E -AU - Manson JE -FAU - Pilz, Stefan -AU - Pilz S -FAU - März, Winfried -AU - März W -FAU - Michaëlsson, Karl -AU - Michaëlsson K -FAU - Lundqvist, Annamari -AU - Lundqvist A -FAU - Jassal, Simerjot K -AU - Jassal SK -FAU - Barrett-Connor, Elizabeth -AU - Barrett-Connor E -FAU - Zhang, Cuilin -AU - Zhang C -FAU - Eaton, Charles B -AU - Eaton CB -FAU - May, Heidi T -AU - May HT -FAU - Anderson, Jeffrey L -AU - Anderson JL -FAU - Sesso, Howard D -AU - Sesso HD -LA - eng -GR - R00-HL095649/HL/NHLBI NIH HHS/United States -GR - R01 CA138962/CA/NCI NIH HHS/United States -GR - R01 HL102122/HL/NHLBI NIH HHS/United States -GR - UL1 RR024140/RR/NCRR NIH HHS/United States -GR - U01 CA138962/CA/NCI NIH HHS/United States -GR - U01 AR45614/AR/NIAMS NIH HHS/United States -GR - U01 AR45654/AR/NIAMS NIH HHS/United States -GR - K99 HL095649/HL/NHLBI NIH HHS/United States -GR - R01-DK088078/DK/NIDDK NIH HHS/United States -GR - U01-AG027810/AG/NIA NIH HHS/United States -GR - ImNIH/Intramural NIH HHS/United States -GR - U01 AR45583/AR/NIAMS NIH HHS/United States -GR - U01 AR45580/AR/NIAMS NIH HHS/United States -GR - CA138962/CA/NCI NIH HHS/United States -GR - U01 AG18197/AG/NIA NIH HHS/United States -GR - HL34594/HL/NHLBI NIH HHS/United States -GR - U01 AR45632/AR/NIAMS NIH HHS/United States -GR - UL1 TR000128/TR/NCATS NIH HHS/United States -GR - R01 DK088078/DK/NIDDK NIH HHS/United States -GR - U01 AR45647/AR/NIAMS NIH HHS/United States -GR - R00 HL095649/HL/NHLBI NIH HHS/United States -GR - L30 DK084809/DK/NIDDK NIH HHS/United States -GR - R01 HL034594/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, N.I.H., Extramural -PT - Research Support, N.I.H., Intramural -PT - Review -DEP - 20121113 -PL - United States -TA - Circ Cardiovasc Qual Outcomes -JT - Circulation. Cardiovascular quality and outcomes -JID - 101489148 -RN - 0 (Biomarkers) -RN - 1406-16-2 (Vitamin D) -RN - A288AR3C9H (25-hydroxyvitamin D) -SB - IM -MH - Biomarkers/blood -MH - Cardiovascular Diseases/blood/*epidemiology/mortality -MH - Humans -MH - Linear Models -MH - Odds Ratio -MH - Prognosis -MH - Prospective Studies -MH - Risk Assessment -MH - Risk Factors -MH - Vitamin D/*analogs & derivatives/blood -MH - Vitamin D Deficiency/blood/*epidemiology/mortality -PMC - PMC3510675 -MID - NIHMS422216 -EDAT- 2012/11/15 06:00 -MHDA- 2013/03/13 06:00 -PMCR- 2013/11/13 -CRDT- 2012/11/15 06:00 -PHST- 2012/11/15 06:00 [entrez] -PHST- 2012/11/15 06:00 [pubmed] -PHST- 2013/03/13 06:00 [medline] -PHST- 2013/11/13 00:00 [pmc-release] -AID - CIRCOUTCOMES.112.967604 [pii] -AID - 10.1161/CIRCOUTCOMES.112.967604 [doi] -PST - ppublish -SO - Circ Cardiovasc Qual Outcomes. 2012 Nov;5(6):819-29. doi: - 10.1161/CIRCOUTCOMES.112.967604. Epub 2012 Nov 13. - -PMID- 18222726 -OWN - NLM -STAT- MEDLINE -DCOM- 20080728 -LR - 20220331 -IS - 1444-2892 (Electronic) -IS - 1443-9506 (Linking) -VI - 17 -IP - 3 -DP - 2008 Jun -TI - Assessment of myocardial viability: comparison of echocardiography versus cardiac - magnetic resonance imaging in the current era. -PG - 173-85 -LID - 10.1016/j.hlc.2007.10.005 [doi] -AB - Detecting viable myocardium, whether hibernating or stunned, is of clinical - significance in patients with coronary artery disease and left ventricular - dysfunction. Echocardiographic assessments of myocardial thickening and - endocardial excursion during dobutamine infusion provide a highly specific marker - for myocardial viability, but with relatively less sensitivity. The additional - modalities of myocardial contrast echocardiography and tissue Doppler have - recently been proposed to provide further, quantitative measures of myocardial - viability assessment. Cardiac magnetic resonance (CMR) has become popular for the - assessment of myocardial viability as it can assess cardiac function, volumes, - myocardial scar, and perfusion with high-spatial resolution. Both 'delayed - enhancement' CMR and dobutamine stress CMR have important roles in the assessment - of patients with ischaemic cardiomyopathy. This article reviews the recent - advances in both echocardiography and CMR for the clinical assessment of - myocardial viability. It attempts to provide a pragmatic approach toward the - patient-specific assessment of this important clinical problem. -FAU - Tomlinson, David R -AU - Tomlinson DR -AD - Department of Cardiology, John Radcliffe Hospital, Oxford OX3 9DU, UK. -FAU - Becher, Harald -AU - Becher H -FAU - Selvanayagam, Joseph B -AU - Selvanayagam JB -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -DEP - 20080128 -PL - Australia -TA - Heart Lung Circ -JT - Heart, lung & circulation -JID - 100963739 -SB - IM -MH - Echocardiography/*methods -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Myocardial Ischemia/*diagnostic imaging/*pathology -MH - Sensitivity and Specificity -RF - 79 -EDAT- 2008/01/29 09:00 -MHDA- 2008/07/29 09:00 -CRDT- 2008/01/29 09:00 -PHST- 2007/05/28 00:00 [received] -PHST- 2007/08/30 00:00 [revised] -PHST- 2007/10/29 00:00 [accepted] -PHST- 2008/01/29 09:00 [pubmed] -PHST- 2008/07/29 09:00 [medline] -PHST- 2008/01/29 09:00 [entrez] -AID - S1443-9506(07)01069-4 [pii] -AID - 10.1016/j.hlc.2007.10.005 [doi] -PST - ppublish -SO - Heart Lung Circ. 2008 Jun;17(3):173-85. doi: 10.1016/j.hlc.2007.10.005. Epub 2008 - Jan 28. - -PMID- 17942581 -OWN - NLM -STAT- MEDLINE -DCOM- 20080410 -LR - 20250529 -IS - 0195-668X (Print) -IS - 0195-668X (Linking) -VI - 28 -IP - 23 -DP - 2007 Dec -TI - Evaluation of the microcirculation in hypertension and cardiovascular disease. -PG - 2834-40 -AB - The ability to investigate the microvascular structure and function is important - in improving our understanding of pathophysiological processes in hypertension - and related cardiovascular disease. A range of techniques are available or - emerging for investigating different aspects of the microcirculation in animals - and humans. Techniques such as experimental intravital microscopy and clinical - intravital microscopy (e.g. orthogonal polarization spectral imaging) allow - visualization at the level of single microvessels. Venous occlusion - plethysmography can be used to measure blood flow in organs, and laser Doppler - flowmetry to measure red cell flux in small areas of tissue. Positron emission - tomography, myocardial contrast echocardiography, and magnetic resonance imaging - provide three-dimensional imaging of local blood flow. The current and potential - clinical usefulness of these different techniques is evaluated. The technical - quality and availability for clinical use of some of the techniques should - improve dramatically during the next few years. 'Molecular imaging'-the - combination of these techniques with genetic, molecular, and computational - approaches-offers great potential for use in research and in diagnosis and the - monitoring of disease progression or the results of therapy. Closer attention to - the microcirculation will ultimately improve the treatment and prevention of many - of the most important forms of cardiovascular disease. -FAU - Struijker-Boudier, Harry A J -AU - Struijker-Boudier HA -AD - CARIM-Cardiovascular Research Institute Maastricht, Maastricht University, - Universiteitssingel 50, PO Box 616, 6200 MD Maastricht, The Netherlands. - hsb@carim.Unimaas.nl -FAU - Rosei, Agabiti E -AU - Rosei AE -FAU - Bruneval, Patrick -AU - Bruneval P -FAU - Camici, Paolo G -AU - Camici PG -FAU - Christ, Frank -AU - Christ F -FAU - Henrion, Daniel -AU - Henrion D -FAU - Lévy, Bernard I -AU - Lévy BI -FAU - Pries, Axel -AU - Pries A -FAU - Vanoverschelde, Jean-Luc -AU - Vanoverschelde JL -LA - eng -GR - MC_U120084164/MRC_/Medical Research Council/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20071017 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*diagnosis/etiology -MH - Coronary Circulation -MH - Diagnostic Imaging/*methods -MH - *Diagnostic Techniques, Cardiovascular -MH - Humans -MH - Hypertension/diagnosis/etiology -MH - Microcirculation -RF - 60 -EDAT- 2007/10/19 09:00 -MHDA- 2008/04/11 09:00 -CRDT- 2007/10/19 09:00 -PHST- 2007/10/19 09:00 [pubmed] -PHST- 2008/04/11 09:00 [medline] -PHST- 2007/10/19 09:00 [entrez] -AID - ehm448 [pii] -AID - 10.1093/eurheartj/ehm448 [doi] -PST - ppublish -SO - Eur Heart J. 2007 Dec;28(23):2834-40. doi: 10.1093/eurheartj/ehm448. Epub 2007 - Oct 17. - -PMID- 22724419 -OWN - NLM -STAT- MEDLINE -DCOM- 20130425 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 18 -IP - 33 -DP - 2012 -TI - Risk of bleeding related to antithrombotic treatment in cardiovascular disease. -PG - 5362-78 -AB - Antithrombotic therapy is a cornerstone of treatment in patients with - cardiovascular disease with bleeding being the most feared complication. This - review describes the risk of bleeding related to different combinations of - antithrombotic drugs used for cardiovascular disease: acute coronary syndrome - (ACS), atrial fibrillation (AF), cerebrovascular (CVD) and peripheral arterial - disease (PAD). Different risk assessment schemes and bleeding definitions are - compared. The HAS-BLED risk score is recommended in patients with AF and in ACS - patients with AF. In patients with ACS with or without a stent dual antiplatelet - therapy with a P2Y12 receptor antagonist and acetylsalicylic acid (ASA) is - recommended for 12 months, preferable with prasugrel or ticagrelor unless there - is an additional indication of warfarin or increased risk of bleeding. In - patients with AF, warfarin is recommended if the risk of stroke is moderate to - high, but newer emerging antithrombotic drugs will be recommended along with/or - preferred to warfarin in the nearby future. Patients with CVD (without - cardiogenic causes) are recommended clopidogrel treatment for secondary - prevention, where as patients with PAD are recommended ASA or clopidogrel. With - future implementation of new antithrombotic treatment regimens as monotherapy and - in combinations with antiplatelet therapy, increased focus on risk of - thromboembolic events and bleeding and individual tailoring of antithrombotic - therapy is warranted. -FAU - Sørensen, Rikke -AU - Sørensen R -AD - Department of Cardiology, Copenhagen University Hospital Gentofte, Niels - Andersens Vej 65, 2900 Hellerup, Denmark. rs@heart.dk. -FAU - Olesen, Jonas B -AU - Olesen JB -FAU - Charlot, Mette -AU - Charlot M -FAU - Gislason, Gunnar H -AU - Gislason GH -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Anticoagulants) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Animals -MH - Anticoagulants/*adverse effects -MH - Cardiovascular Diseases/blood/*drug therapy -MH - Drug Therapy, Combination -MH - Fibrinolytic Agents/*adverse effects -MH - Hemorrhage/*chemically induced -MH - Humans -MH - Patient Selection -MH - Platelet Aggregation Inhibitors/*adverse effects -MH - Risk Assessment -MH - Risk Factors -MH - Treatment Outcome -EDAT- 2012/06/26 06:00 -MHDA- 2013/04/26 06:00 -CRDT- 2012/06/26 06:00 -PHST- 2012/04/16 00:00 [received] -PHST- 2012/05/01 00:00 [accepted] -PHST- 2012/06/26 06:00 [entrez] -PHST- 2012/06/26 06:00 [pubmed] -PHST- 2013/04/26 06:00 [medline] -AID - CPD-EPUB-20120619-12 [pii] -AID - 10.2174/138161212803251970 [doi] -PST - ppublish -SO - Curr Pharm Des. 2012;18(33):5362-78. doi: 10.2174/138161212803251970. - -PMID- 19910222 -OWN - NLM -STAT- MEDLINE -DCOM- 20100225 -LR - 20250623 -IS - 1532-2165 (Electronic) -IS - 1078-5884 (Linking) -VI - 39 -IP - 1 -DP - 2010 Jan -TI - A systematic review of implementation of established recommended secondary - prevention measures in patients with PAOD. -PG - 70-86 -LID - 10.1016/j.ejvs.2009.09.027 [doi] -AB - OBJECTIVE: Since patients with peripheral arterial occlusive disease (PAOD) are - at high-risk for cardiovascular morbidity and mortality, preventive measures - aimed to reduce cardiovascular adverse events are advocated in the current - guidelines. We conducted a systematic review to assess the implementation of - secondary prevention (SP) measures in PAOD patients. METHODS: PubMed, Cochrane - Library, EMBASE and Web of Science databases were searched to perform a - systematic review of the literature from 1999 till June 2008 on SP for PAOD - patients. Assessment of study quality was done following the Cochrane Library - review system. The record outcomes were antiplatelet agents, heart rate lowering - agents, blood pressure lowering agents, lipid lowering agents, glucose lowering - agents, smoking cessation and walking exercise. RESULTS: From a total of 2137 - identified studies, 83 observational studies met the inclusion criteria, of which - 24 were included in the systematic review comprising 34 157 patients. These - patients suffered from coronary artery disease (n=3516, 41%), myocardial - infraction (n=2647, 38%), angina pectoris (n=1790, 31%), congestive heart failure - (n=2052, 14%), diabetes mellitus (n=10 690, 31%),hypertension (n=20 823, 73%) and - hyperlipidaemia (n=15 067, 64%). Contrary to what the guidelines prescribe, - antiplatelet agents, heart rate lowering agents, blood pressure lowering agents - and lipid lowering agents were prescribed in 63%, 34%, 46% and 45% of the - patients, respectively. Glucose lowering agents were prescribed in 81% and - smoking cessation in 39% of the patients. CONCLUSION: The majority of patients - suffering from PAOD do not receive the entire approach of SP measures as - suggested by the current guidelines. To our knowledge, the cause of this - undertreatment is multifactorial: patient, physician or health-care-related. -CI - Copyright 2009 European Society for Vascular Surgery. Published by Elsevier Ltd. - All rights reserved. -FAU - Flu, H C -AU - Flu HC -AD - Department of Vascular Surgery, Leiden University Medical Centre, Leiden, The - Netherlands. -FAU - Tamsma, J T -AU - Tamsma JT -FAU - Lindeman, J H N -AU - Lindeman JH -FAU - Hamming, J F -AU - Hamming JF -FAU - Lardenoye, J H P -AU - Lardenoye JH -LA - eng -PT - Journal Article -PT - Systematic Review -DEP - 20091111 -PL - England -TA - Eur J Vasc Endovasc Surg -JT - European journal of vascular and endovascular surgery : the official journal of - the European Society for Vascular Surgery -JID - 9512728 -RN - 0 (Cardiovascular Agents) -SB - IM -CIN - Eur J Vasc Endovasc Surg. 2010 Jan;39(1):87-8. doi: 10.1016/j.ejvs.2009.10.010. - PMID: 19906546 -MH - Aged -MH - Arterial Occlusive Diseases/complications/*therapy -MH - Cardiovascular Agents/*therapeutic use -MH - Cardiovascular Diseases/etiology/*prevention & control -MH - Evidence-Based Medicine -MH - Exercise -MH - Female -MH - Guideline Adherence -MH - Humans -MH - Male -MH - Middle Aged -MH - Peripheral Vascular Diseases/complications/*therapy -MH - Practice Guidelines as Topic -MH - Risk Assessment -MH - Risk Factors -MH - *Risk Reduction Behavior -MH - *Secondary Prevention -MH - Smoking Cessation -MH - Walking -RF - 73 -EDAT- 2009/11/17 06:00 -MHDA- 2010/02/26 06:00 -CRDT- 2009/11/14 06:00 -PHST- 2009/06/09 00:00 [received] -PHST- 2009/09/21 00:00 [accepted] -PHST- 2009/11/14 06:00 [entrez] -PHST- 2009/11/17 06:00 [pubmed] -PHST- 2010/02/26 06:00 [medline] -AID - S1078-5884(09)00513-9 [pii] -AID - 10.1016/j.ejvs.2009.09.027 [doi] -PST - ppublish -SO - Eur J Vasc Endovasc Surg. 2010 Jan;39(1):70-86. doi: 10.1016/j.ejvs.2009.09.027. - Epub 2009 Nov 11. - -PMID- 23304015 -OWN - NLM -STAT- MEDLINE -DCOM- 20130611 -LR - 20211021 -IS - 1526-6702 (Electronic) -IS - 0730-2347 (Print) -IS - 0730-2347 (Linking) -VI - 39 -IP - 6 -DP - 2012 -TI - Extreme thrombocytosis and cardiovascular surgery: risks and management. -PG - 792-8 -AB - Extreme thrombocytosis is a major risk factor for excessive bleeding and for - thrombosis, either of which can complicate cardiovascular surgical and - interventional procedures. Extreme thrombocytosis can also cause an unusual - syndrome, erythromelalgia, that results in a type of chronic microvascular - occlusive arterial disease. We present the differential diagnosis of conditions - that may lead to extreme thrombocytosis, 3 cases (each of which illustrates a - different potential complication), and a review of the pertinent medical - literature. Correcting excessive thrombocytosis is typically not difficult, - whether electively or acutely, and effective therapy usually controls thrombosis - and excessive hemorrhage post-procedurally. -FAU - Natelson, Ethan A -AU - Natelson EA -AD - Department of Academic Medicine, Weill-Cornell Medical College, and The Methodist - Hospital, Houston, Texas 77030, USA. enatelson@tmhs.org -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - Tex Heart Inst J -JT - Texas Heart Institute journal -JID - 8214622 -RN - 0 (Immunosuppressive Agents) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Adult -MH - Aged -MH - *Cardiovascular Surgical Procedures -MH - Diagnosis, Differential -MH - Female -MH - Humans -MH - Immunosuppressive Agents/*therapeutic use -MH - Male -MH - Middle Aged -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Plateletpheresis/*methods -MH - Postoperative Hemorrhage/blood/*etiology/prevention & control -MH - Risk Factors -MH - *Thrombocytosis/complications/diagnosis/therapy -MH - Thrombosis/blood/*etiology/prevention & control -PMC - PMC3528235 -OTO - NOTNLM -OT - Coronary thrombosis/prevention & control/surgery -OT - erythromelalgia -OT - hemorrhage/drug therapy -OT - hydroxyurea/therapeutic use -OT - myeloproliferative disorders/genetics/pathology -OT - plateletpheresis -OT - polycythemia vera/blood -OT - preoperative care/methods -OT - risk factors -OT - thrombocythemia, - essential/complications/diagnosis/etiology/genetics/metabolism/physiopathology -EDAT- 2013/01/11 06:00 -MHDA- 2013/06/12 06:00 -PMCR- 2012/01/01 -CRDT- 2013/01/11 06:00 -PHST- 2013/01/11 06:00 [entrez] -PHST- 2013/01/11 06:00 [pubmed] -PHST- 2013/06/12 06:00 [medline] -PHST- 2012/01/01 00:00 [pmc-release] -AID - 0010801-201212000-00004 [pii] -PST - ppublish -SO - Tex Heart Inst J. 2012;39(6):792-8. - -PMID- 16445715 -OWN - NLM -STAT- MEDLINE -DCOM- 20060413 -LR - 20131121 -IS - 0305-1870 (Print) -IS - 0305-1870 (Linking) -VI - 33 -IP - 1-2 -DP - 2006 Jan-Feb -TI - Convergence of glucose- and fatty acid-induced abnormal myocardial - excitation-contraction coupling and insulin signalling. -PG - 152-8 -AB - 1. Myocardial insulin resistance and abnormal Ca(2+) regulation are hallmarks of - hypertrophic and diabetic hearts, but deprivation of energetic substrates does - not tell the whole story. Is there a link between the aetiology of these - dysfunctions? 2. Diabetic cardiomyopathy is defined as phenotypic changes in the - heart muscle cell independent of associated coronary vascular disease. The - cellular consequences of diabetes on excitation-contraction (E-C) coupling and - insulin signalling are presented in various models of diabetes in order to set - the stage for exploring the pathogenesis of heart disease. 3. Excess glucose or - fatty acids can lead to augmented flux through the hexosamine biosynthesis - pathway (HBP). The formation of uridine 5 cent-diphosphate-hexosamines has been - shown to be involved in abnormal E-C coupling and myocardial insulin resistance. - 4. There is growing evidence that O-linked glycosylation (downstream of HBP) may - regulate the function of cytosolic and nuclear proteins in a dynamic manner, - similar to phosphorylation and perhaps involving reciprocal or synergistic - modification of serine/threonine sites. 5. This review focuses on the question of - whether there is a role for HBP and dynamic O-linked glycosylation in the - development of myocardial insulin resistance and abnormal E-C coupling. The - emerging concept that O-linked glycosylation is a regulatory, post-translational - modification of cytosolic/nuclear proteins that interacts with phosphorylation in - the heart is explored. -FAU - Davidoff, Amy J -AU - Davidoff AJ -AD - Department of Pharmacology, College of Osteopathic Medicine, University of New - England, Biddeford, ME, USA. adavidoff@une.edu -LA - eng -GR - R01-HL66895/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Australia -TA - Clin Exp Pharmacol Physiol -JT - Clinical and experimental pharmacology & physiology -JID - 0425076 -RN - 0 (Fatty Acids) -RN - 0 (Hexosamines) -RN - EC 2.7.10.1 (Receptor, Insulin) -RN - IY9XDZ35W2 (Glucose) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Animals -MH - Calcium/metabolism -MH - Cardiomyopathies/etiology/metabolism/physiopathology -MH - Diabetes Mellitus, Experimental/complications/metabolism/physiopathology -MH - Fatty Acids/*metabolism -MH - Glucose/*metabolism -MH - Glycosylation -MH - Hexosamines/*metabolism -MH - Humans -MH - *Insulin Resistance -MH - Models, Biological -MH - Receptor, Insulin/physiology -MH - Signal Transduction/*physiology -RF - 77 -EDAT- 2006/02/01 09:00 -MHDA- 2006/04/14 09:00 -CRDT- 2006/02/01 09:00 -PHST- 2006/02/01 09:00 [pubmed] -PHST- 2006/04/14 09:00 [medline] -PHST- 2006/02/01 09:00 [entrez] -AID - CEP [pii] -AID - 10.1111/j.1440-1681.2006.04343.x [doi] -PST - ppublish -SO - Clin Exp Pharmacol Physiol. 2006 Jan-Feb;33(1-2):152-8. doi: - 10.1111/j.1440-1681.2006.04343.x. - -PMID- 24291279 -OWN - NLM -STAT- MEDLINE -DCOM- 20140422 -LR - 20220408 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Print) -IS - 0735-1097 (Linking) -VI - 63 -IP - 8 -DP - 2014 Mar 4 -TI - Frailty assessment in the cardiovascular care of older adults. -PG - 747-62 -LID - S0735-1097(13)06155-X [pii] -LID - 10.1016/j.jacc.2013.09.070 [doi] -AB - Due to the aging and increasingly complex nature of our patients, frailty has - become a high-priority theme in cardiovascular medicine. Despite the recognition - of frailty as a pivotal element in the evaluation of older adults with - cardiovascular disease (CVD), there has yet to be a road map to facilitate its - adoption in routine clinical practice. Thus, we sought to synthesize the existing - body of evidence and offer a perspective on how to integrate frailty into - clinical practice. Frailty is a biological syndrome that reflects a state of - decreased physiological reserve and vulnerability to stressors. Upward of 20 - frailty assessment tools have been developed, with most tools revolving around - the core phenotypic domains of frailty-slow walking speed, weakness, inactivity, - exhaustion, and shrinking-as measured by physical performance tests and - questionnaires. The prevalence of frailty ranges from 10% to 60%, depending on - the CVD burden, as well as the tool and cutoff chosen to define frailty. - Epidemiological studies have consistently demonstrated that frailty carries a - relative risk of >2 for mortality and morbidity across a spectrum of stable CVD, - acute coronary syndromes, heart failure, and surgical and transcatheter - interventions. Frailty contributes valuable prognostic insights incremental to - existing risk models and assists clinicians in defining optimal care pathways for - their patients. Interventions designed to improve outcomes in frail elders with - CVD such as multidisciplinary cardiac rehabilitation are being actively tested. - Ultimately, frailty should not be viewed as a reason to withhold care but rather - as a means of delivering it in a more patient-centered fashion. -CI - Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Afilalo, Jonathan -AU - Afilalo J -AD - Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital, - McGill University, Montreal, Quebec, Canada. Electronic address: - jonathan.afilalo@mcgill.ca. -FAU - Alexander, Karen P -AU - Alexander KP -AD - Division of Cardiology, Duke University Medical Center, Durham, North Carolina. -FAU - Mack, Michael J -AU - Mack MJ -AD - Division of Cardiothoracic Surgery, Baylor Health Care System, The Heart Hospital - Baylor Plano, Plano, Texas. -FAU - Maurer, Mathew S -AU - Maurer MS -AD - Division of Cardiology, Columbia University Medical Center, New York, New York. -FAU - Green, Philip -AU - Green P -AD - Division of Cardiology, Columbia University Medical Center, New York, New York. -FAU - Allen, Larry A -AU - Allen LA -AD - Division of Cardiology, University of Colorado School of Medicine, Aurora, - Colorado. -FAU - Popma, Jeffrey J -AU - Popma JJ -AD - Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, - Massachusetts. -FAU - Ferrucci, Luigi -AU - Ferrucci L -AD - National Institute on Aging, National Institutes of Health, Baltimore, Maryland. -FAU - Forman, Daniel E -AU - Forman DE -AD - Division of Cardiovascular Medicine, Brigham and Women's Hospital, VA Boston - Healthcare Center, Boston, Massachusetts. -LA - eng -GR - K23 HL121142/HL/NHLBI NIH HHS/United States -GR - L30 AG040558/AG/NIA NIH HHS/United States -PT - Journal Article -PT - Review -DEP - 20131127 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Cardiovascular Diseases/*diagnosis/psychology -MH - *Frail Elderly/psychology -MH - *Geriatric Assessment/methods -MH - Humans -MH - Prospective Studies -MH - Retrospective Studies -MH - Surveys and Questionnaires/*standards -PMC - PMC4571179 -MID - NIHMS639665 -OTO - NOTNLM -OT - cardiovascular disease -OT - elderly -OT - frailty -EDAT- 2013/12/03 06:00 -MHDA- 2014/04/23 06:00 -PMCR- 2015/09/16 -CRDT- 2013/12/03 06:00 -PHST- 2013/09/25 00:00 [received] -PHST- 2013/09/25 00:00 [revised] -PHST- 2013/09/30 00:00 [accepted] -PHST- 2013/12/03 06:00 [entrez] -PHST- 2013/12/03 06:00 [pubmed] -PHST- 2014/04/23 06:00 [medline] -PHST- 2015/09/16 00:00 [pmc-release] -AID - S0735-1097(13)06155-X [pii] -AID - 10.1016/j.jacc.2013.09.070 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2014 Mar 4;63(8):747-62. doi: 10.1016/j.jacc.2013.09.070. Epub - 2013 Nov 27. - -PMID- 24281316 -OWN - NLM -STAT- MEDLINE -DCOM- 20140902 -LR - 20151119 -IS - 1940-4034 (Electronic) -IS - 1074-2484 (Linking) -VI - 19 -IP - 1 -DP - 2014 Jan -TI - Pharmacologic therapy for erectile dysfunction and its interaction with the - cardiovascular system. -PG - 53-64 -LID - 10.1177/1074248413504034 [doi] -AB - Phosphodiesterase (PDE) enzymes are widely distributed throughout the body, - having numerous effects and functions. The PDE type 5 (PDE5) inhibitors are - widely used to treat erectile dysfunction (ED). Recent, intense preclinical and - clinical research with PDE5 inhibitors has shed light on new mechanisms and has - revealed a number of pleiotropic effects on the cardiovascular (CV) system. To - date, PDE5 inhibition has been shown to be effective for the treatment of - idiopathic pulmonary arterial hypertension, and both sildenafil and tadalafil are - approved for this indication. However, current or future PDE5 inhibitors have the - potential of becoming clinically useful in a variety of CV conditions such as - heart failure, coronary artery disease, and hypertension. The present review - discusses recent findings regarding pharmacologic treatment of ED and its - interaction with the CV system and highlights current and future clinical - applications beyond ED. -FAU - Ioakeimidis, Nikolaos -AU - Ioakeimidis N -AD - 1First Department of Cardiology, Cardiovascular Diseases and Sexual Health Unit, - Athens Medical School, Hippokration Hospital, Athens, Greece. -FAU - Kostis, John B -AU - Kostis JB -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131125 -PL - United States -TA - J Cardiovasc Pharmacol Ther -JT - Journal of cardiovascular pharmacology and therapeutics -JID - 9602617 -RN - 0 (Carbolines) -RN - 0 (Phosphodiesterase 5 Inhibitors) -RN - 0 (Piperazines) -RN - 0 (Purines) -RN - 0 (Sulfones) -RN - 742SXX0ICT (Tadalafil) -RN - BW9B0ZE037 (Sildenafil Citrate) -RN - EC 3.1.4.- (Phosphoric Diester Hydrolases) -SB - IM -MH - Animals -MH - Carbolines/pharmacology/therapeutic use -MH - Cardiovascular Diseases/*drug therapy/physiopathology -MH - Cardiovascular System/drug effects/physiopathology -MH - Erectile Dysfunction/*drug therapy/physiopathology -MH - Familial Primary Pulmonary Hypertension -MH - Humans -MH - Hypertension, Pulmonary/drug therapy/physiopathology -MH - Male -MH - Phosphodiesterase 5 Inhibitors/pharmacology/*therapeutic use -MH - Phosphoric Diester Hydrolases/drug effects/metabolism -MH - Piperazines/pharmacology/therapeutic use -MH - Purines/pharmacology/therapeutic use -MH - Sildenafil Citrate -MH - Sulfones/pharmacology/therapeutic use -MH - Tadalafil -OTO - NOTNLM -OT - PDE5 inhibitors -OT - cardiovascular disease -OT - erectile dysfunction -EDAT- 2013/11/28 06:00 -MHDA- 2014/09/03 06:00 -CRDT- 2013/11/28 06:00 -PHST- 2013/11/28 06:00 [entrez] -PHST- 2013/11/28 06:00 [pubmed] -PHST- 2014/09/03 06:00 [medline] -AID - 1074248413504034 [pii] -AID - 10.1177/1074248413504034 [doi] -PST - ppublish -SO - J Cardiovasc Pharmacol Ther. 2014 Jan;19(1):53-64. doi: 10.1177/1074248413504034. - Epub 2013 Nov 25. - -PMID- 23597106 -OWN - NLM -STAT- MEDLINE -DCOM- 20131231 -LR - 20191112 -IS - 1875-6182 (Electronic) -IS - 1871-5257 (Linking) -VI - 11 -IP - 2 -DP - 2013 Jun -TI - Combined antiplatelet therapy: still a sweeping combination in cardiology. -PG - 136-67 -AB - Platelets play a key role in the pathogenesis of atherothrombosis, involved in - both the development and progression of atherosclerotic heart disease, and the - attendant acute thrombotic complications. Antiplatelet therapy constitutes a - mainstay therapy for patients with acute coronary syndromes and generally - high-risk patients with atherothrombosis. Until recently, dual antiplatelet - therapy (DAPT) for the treatment and prevention of the complications of - atherothrombotic disease was traditionally limited to aspirin plus clopidogrel. - However, a most important pertaining issue emerged, that of the occurrence of - drug-resistance or tolerance observed in some patients for both these - antithrombotic agents, which limited the efficacy and applicability of this - combined therapy.The availability of the newer thienopyridine, prasugrel, and the - cyclopentyl-triazolopyrimidine, ticagrelor, represents an important addition to - the physician's armamentarium. Dual antiplatelet therapy with aspirin and - clopidogrel or one of the newer agents interferes with platelet activation in - complementary, but separate pathways. Aspirin irreversibly inhibits - cyclooxygenase, thus preventing the production of thromboxane A2, which is a - prothrombotic and vasoconstrictive substance. Thienopyridines - (clopidogrel/prasugrel) irreversibly and ticagrelor reversibly prevent and - inhibit platelet activation by blocking one of the three known adenosine - 5'-diphosphate (ADP) receptors (the P2Y12 receptor) on the platelet surface, thus - interfering with platelet activation, degranulation and aggregation. Each of - these antiplatelet agents has a protective effect against adverse vascular - events; classical DAPT with aspirin and clopidogrel has an even stronger - antiplatelet effect compared with either agent alone, however DAPT combining - aspirin with one of the newer more potent agents translates into superior - antithrombotic protection in atherothrobotic vascular disease, albeit at an - increased, though not inordinately, risk for bleeding complications. A number of - randomized clinical trials have demonstrated and confirmed the incremental - benefit and efficacy of DAPT with use of either classical or newer agents, above - and beyond that of each antiplatelet agent alone. Data have also been obtained - from studies where indications for the use of DAPT continue to expand into other - patient groups, rendering and maintaining DAPT a sweeping combination in - Cardiology. This article is a comprehensive review of all these data and the - landmark trials on the two classical and also the newer antiplatelet agents, the - issues involved and the current recommendations for their use in patients with - atherosclerotic heart disease and other cardiovascular disorders and procedures. -FAU - Manolis, Antonis S -AU - Manolis AS -AD - First Department of Cardiology, Evagelismos General Hospital of Athens, Athens, - Greece. asmanol@otenet.gr -FAU - Manolis, Theodora A -AU - Manolis TA -FAU - Papadimitriou, Prokopis -AU - Papadimitriou P -FAU - Koulouris, Spyros -AU - Koulouris S -FAU - Melita, Helen -AU - Melita H -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiovasc Hematol Agents Med Chem -JT - Cardiovascular & hematological agents in medicinal chemistry -JID - 101266881 -RN - 0 (Platelet Aggregation Inhibitors) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Aspirin/pharmacology/therapeutic use -MH - Blood Platelets/drug effects -MH - Cardiovascular Diseases/*drug therapy/prevention & control -MH - Clinical Trials as Topic -MH - Drug Therapy, Combination/standards/trends -MH - Humans -MH - Platelet Aggregation Inhibitors/pharmacology/*therapeutic use -EDAT- 2013/04/20 06:00 -MHDA- 2014/01/01 06:00 -CRDT- 2013/04/20 06:00 -PHST- 2013/03/20 00:00 [received] -PHST- 2013/04/03 00:00 [revised] -PHST- 2013/04/04 00:00 [accepted] -PHST- 2013/04/20 06:00 [entrez] -PHST- 2013/04/20 06:00 [pubmed] -PHST- 2014/01/01 06:00 [medline] -AID - CMCCHA-EPUB-20130408-1 [pii] -AID - 10.2174/1871525711311020009 [doi] -PST - ppublish -SO - Cardiovasc Hematol Agents Med Chem. 2013 Jun;11(2):136-67. doi: - 10.2174/1871525711311020009. - -PMID- 24083219 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20211021 -IS - 2250-1541 (Print) -IS - 1947-2714 (Electronic) -IS - 1947-2714 (Linking) -VI - 5 -IP - 8 -DP - 2013 Aug -TI - Cardiovascular repercussions of the pseudoexfoliation syndrome. -PG - 454-9 -LID - 10.4103/1947-2714.117294 [doi] -AB - Pseudoexfoliation syndrome is a primarily ophthalmological disorder caused by - deposition of whitish-gray protein on the lens, iris, and multiple other eye - tissues. There is increasing evidence over the previous years that - pseudoexfoliation syndrome is a systemic disorder with various extraocular - manifestations and has recently been linked to several cardiovascular disorders. - The present article aims to summarize the current knowledge on cardiovascular - implications of this well-described clinical entity. -FAU - Katsi, Vasiliki -AU - Katsi V -AD - Department of Cardiology, Hippokration Hospital, Athens, Greece. -FAU - Pavlidis, Antonios N -AU - Pavlidis AN -FAU - Kallistratos, Manolis S -AU - Kallistratos MS -FAU - Fitsios, Athanasios -AU - Fitsios A -FAU - Bratsas, Athanasios -AU - Bratsas A -FAU - Tousoulis, Dimitris -AU - Tousoulis D -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -FAU - Manolis, Athanasios J -AU - Manolis AJ -FAU - Kallikazaros, Ioannis -AU - Kallikazaros I -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - N Am J Med Sci -JT - North American journal of medical sciences -JID - 101521411 -PMC - PMC3784921 -OTO - NOTNLM -OT - Cardiovascular -OT - Coronary disease -OT - Pseudoexfoliation syndrome -COIS- Conflict of Interest: None declared. -EDAT- 2013/10/02 06:00 -MHDA- 2013/10/02 06:01 -PMCR- 2013/08/01 -CRDT- 2013/10/02 06:00 -PHST- 2013/10/02 06:00 [entrez] -PHST- 2013/10/02 06:00 [pubmed] -PHST- 2013/10/02 06:01 [medline] -PHST- 2013/08/01 00:00 [pmc-release] -AID - NAJMS-5-454 [pii] -AID - 10.4103/1947-2714.117294 [doi] -PST - ppublish -SO - N Am J Med Sci. 2013 Aug;5(8):454-9. doi: 10.4103/1947-2714.117294. - -PMID- 22709742 -OWN - NLM -STAT- MEDLINE -DCOM- 20120823 -LR - 20121115 -IS - 1097-6744 (Electronic) -IS - 0002-8703 (Linking) -VI - 163 -IP - 6 -DP - 2012 Jun -TI - From pressure overload to volume overload: aortic regurgitation after - transcatheter aortic valve implantation. -PG - 903-11 -LID - 10.1016/j.ahj.2012.03.017 [doi] -AB - Severe aortic valve stenosis is a common valvular heart disease that is - characterized by left ventricular (LV) pressure overload. A lasting effect of - pressure overload is LV remodeling, accompanied by concentric hypertrophy and - increased myocardial stiffness. Transcatheter aortic valve implantation (TAVI) - has emerged as an alternative to surgical aortic valve replacement for patients - with severe symptomatic aortic valve stenosis and high surgical risk. Although - TAVI has favorable hemodynamic performance, aortic valve regurgitation (AR) is - the most frequent complication because of the specific technique used for - implantation of transcatheter valves. During implantation, the calcified native - valve is pushed aside, and the prosthesis usually achieves only an incomplete - prosthesis apposition. As a consequence, the reported prevalence of moderate and - severe AR after TAVI is 6% to 21%, which is considerably higher than that after a - surgical valve replacement. Although mild AR probably has minor hemodynamic - effects, even moderate AR might result in serious consequences. In moderate and - severe AR after TAVI, a normal-sized LV with increased myocardial stiffness has - been exposed to volume overload. Because the noncompliant LV is unable to raise - end-diastolic volume, the end-diastolic pressure increases, and the forward - stroke volume decreases. In recent years, an increasing number of patients have - successfully undergone TAVI. Despite encouraging overall results, a substantial - number of patients receive neither symptomatic nor prognostic benefits from TAVI. - Aortic valve regurgitation has been considered a potential contributor to - morbidity and mortality after TAVI. Therefore, various strategies and - improvements in valve designs are mandatory to reduce the prevalence of AR after - TAVI. -CI - Copyright © 2012 Mosby, Inc. All rights reserved. -FAU - Gotzmann, Michael -AU - Gotzmann M -AD - Cardiology and Angiology, BG University-Hospital Bergmannsheil, - Bürkle-de-la-Camp-Platz 1, Bochum, Germany. michael_gotzmann@web.de -FAU - Lindstaedt, Michael -AU - Lindstaedt M -FAU - Mügge, Andreas -AU - Mügge A -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am Heart J -JT - American heart journal -JID - 0370465 -SB - IM -MH - Aortic Valve Insufficiency/diagnosis/*etiology/*physiopathology -MH - Aortic Valve Stenosis/physiopathology/*surgery -MH - Catheterization -MH - Coronary Angiography -MH - Echocardiography, Transesophageal -MH - Heart Valve Prosthesis -MH - Heart Valve Prosthesis Implantation/*adverse effects/*methods -MH - Humans -MH - Prevalence -MH - Ventricular Pressure -EDAT- 2012/06/20 06:00 -MHDA- 2012/08/24 06:00 -CRDT- 2012/06/20 06:00 -PHST- 2011/09/08 00:00 [received] -PHST- 2012/03/21 00:00 [accepted] -PHST- 2012/06/20 06:00 [entrez] -PHST- 2012/06/20 06:00 [pubmed] -PHST- 2012/08/24 06:00 [medline] -AID - S0002-8703(12)00183-4 [pii] -AID - 10.1016/j.ahj.2012.03.017 [doi] -PST - ppublish -SO - Am Heart J. 2012 Jun;163(6):903-11. doi: 10.1016/j.ahj.2012.03.017. - -PMID- 22563098 -OWN - NLM -STAT- MEDLINE -DCOM- 20120619 -LR - 20250626 -IS - 1756-1833 (Electronic) -IS - 0959-8138 (Print) -IS - 0959-8138 (Linking) -VI - 344 -DP - 2012 May 4 -TI - Risk of cardiovascular serious adverse events associated with varenicline use for - tobacco cessation: systematic review and meta-analysis. -PG - e2856 -LID - bmj.e2856 [pii] -LID - 10.1136/bmj.e2856 [doi] -LID - e2856 -AB - OBJECTIVE: To examine the risk of treatment emergent, cardiovascular serious - adverse events associated with varenicline use for tobacco cessation. DESIGN: - Meta-analysis comparing study effects using four summary estimates. DATA SOURCES: - Medline, Cochrane Library, online clinical trials registries, and reference lists - of identified articles. REVIEW METHODS: We included randomised controlled trials - of current tobacco users of adult age comparing use of varenicline with an - inactive control and reporting adverse events. We defined treatment emergent, - cardiovascular serious adverse events as occurring during drug treatment or - within 30 days of discontinuation, and included any ischaemic or arrhythmic - adverse cardiovascular event (myocardial infarction, unstable angina, coronary - revascularisation, coronary artery disease, arrhythmias, transient ischaemic - attacks, stroke, sudden death or cardiovascular related death, or congestive - heart failure). RESULTS: We identified 22 trials; all were double blinded and - placebo controlled; two included participants with active cardiovascular disease - and 11 enrolled participants with a history of cardiovascular disease. Rates of - treatment emergent, cardiovascular serious adverse events were 0.63% (34/5431) in - the varenicline groups and 0.47% (18/3801) in the placebo groups. The summary - estimate for the risk difference, 0.27% (95% confidence interval -0.10 to 0.63; P - = 0.15), based on all 22 trials, was neither clinically nor statistically - significant. For comparison, the relative risk (1.40, 0.82 to 2.39; P = 0.22), - Mantel-Haenszel odds ratio (1.41, 0.82 to 2.42; P = 0.22), and Peto odds ratio - (1.58, 0.90 to 2.76; P = 0.11), all based on 14 trials with at least one event, - also indicated a non-significant difference between varenicline and placebo - groups. CONCLUSIONS: This meta--analysis--which included all trials published to - date, focused on events occurring during drug exposure, and analysed findings - using four summary estimates-found no significant increase in cardiovascular - serious adverse events associated with varenicline use. For rare outcomes, - summary estimates based on absolute effects are recommended and estimates based - on the Peto odds ratio should be avoided. -FAU - Prochaska, Judith J -AU - Prochaska JJ -AD - Department of Psychiatry and Center for Tobacco Control Research and Education, - University of California, San Francisco, CA 94143-0984, USA. JProchaska@ucsf.edu -FAU - Hilton, Joan F -AU - Hilton JF -LA - eng -GR - R01 MH083684/MH/NIMH NIH HHS/United States -GR - P50 DA09253/DA/NIDA NIH HHS/United States -GR - R34 DA030538/DA/NIDA NIH HHS/United States -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, N.I.H., Extramural -PT - Systematic Review -DEP - 20120504 -PL - England -TA - BMJ -JT - BMJ (Clinical research ed.) -JID - 8900488 -RN - 0 (Benzazepines) -RN - 0 (Nicotinic Agonists) -RN - 0 (Quinoxalines) -RN - W6HS99O8ZO (Varenicline) -SB - IM -CIN - BMJ. 2012 Jun 12;344:e3873; author reply e4033. doi: 10.1136/bmj.e3873. PMID: - 22693049 -CIN - Ann Intern Med. 2012 Aug 21;157(4):JC2-2. doi: - 10.7326/0003-4819-157-4-201208210-02002. PMID: 22910956 -CIN - Praxis (Bern 1994). 2012 Aug 22;101(17):1128-9. doi: 10.1024/1661-8157/a001046. - PMID: 22915518 -CIN - BMJ. 2013 Feb 26;346:f1092. doi: 10.1136/bmj.f1092. PMID: 23444433 -MH - Adult -MH - Benzazepines/*adverse effects -MH - Cardiovascular Diseases/*chemically induced -MH - Female -MH - Humans -MH - Male -MH - Nicotinic Agonists/*adverse effects -MH - Quinoxalines/*adverse effects -MH - Randomized Controlled Trials as Topic -MH - Risk Factors -MH - Tobacco Use Cessation/*methods -MH - Tobacco Use Disorder/drug therapy -MH - Treatment Outcome -MH - Varenicline -PMC - PMC3344735 -COIS- Competing interests: All authors have completed the Unified Competing Interest - form at www.icmje.org/coi_disclosure.pdf (available on request from the - corresponding author) and declare: this study received support from the National - Institute on Drug Abuse and the State of California Tobacco-Related Disease - Research Program; JJP is principal investigator on R01 MH083684 from the National - Institute of Mental Health and an Investigator Initiated Research award from - Pfizer (WS981308), and is a collaborator on R34 DA030538 from the National - Institute on Drug Abuse and a Cahan Award from the Flight Attendant Medical - Research Institute, all of which are tobacco control trials; JFH is - coinvestigator on five randomised controlled trials funded by the National - Institutes of Health and the Agency for Healthcare Research and Quality, none of - which are relevant to the submitted work; JFH has had no relationship with any - company that might have an interest in the submitted work in the previous three - years; no other relationships or activities that could appear to have influenced - the submitted work. -EDAT- 2012/05/09 06:00 -MHDA- 2012/06/20 06:00 -PMCR- 2012/05/04 -CRDT- 2012/05/08 06:00 -PHST- 2012/05/08 06:00 [entrez] -PHST- 2012/05/09 06:00 [pubmed] -PHST- 2012/06/20 06:00 [medline] -PHST- 2012/05/04 00:00 [pmc-release] -AID - bmj.e2856 [pii] -AID - proj003451 [pii] -AID - 10.1136/bmj.e2856 [doi] -PST - epublish -SO - BMJ. 2012 May 4;344:e2856. doi: 10.1136/bmj.e2856. - -PMID- 22668801 -OWN - NLM -STAT- MEDLINE -DCOM- 20140402 -LR - 20151119 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 167 -IP - 3 -DP - 2013 Aug 10 -TI - HDL-C: does it matter? An update on novel HDL-directed pharmaco-therapeutic - strategies. -PG - 646-55 -LID - S0167-5273(12)00666-3 [pii] -LID - 10.1016/j.ijcard.2012.05.052 [doi] -AB - It has long been recognized that elevated levels of low-density lipoprotein - cholesterol (LDL-C) increase the risk of cardiovascular disease (CHD) and that - pharmacologic therapy to decrease LDL-C significantly reduces cardiovascular - events. Despite the effectiveness of statins for CHD risk reduction, even optimal - LDL-lowering therapy alone fails to avert 60% to 70% of CHD cases. A low plasma - concentration of high-density lipoprotein cholesterol (HDL-C) is also associated - with increased risk of CHD. However, the convincing epidemiologic data linking - HDL cholesterol (HDL-C) to CHD risk in an inverse correlation has not yet - translated into clinical trial evidence supporting linearity between HDL-C - increases and CHD risk reduction. It is becoming clear that a functional HDL is a - more desirable target than simply increasing HDL-C levels. Discoveries in the - past decade have shed light on the complex metabolic and antiatherosclerotic - pathways of HDL. These insights, in turn, have fueled the development of new - HDL-targeted drugs, which can be classified according to four different - therapeutic approaches: directly augmenting the concentration of apolipoprotein - A-I (apo A-I), the major protein constituent of HDL; indirectly augmenting the - concentration of apo A-I and HDL cholesterol; mimicking the functionality of apo - A-I and enhancing reverse cholesterol transport. This review discusses the latest - in novel HDL directed therapeutic strategies. -CI - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved. -FAU - Gadi, Ramprasad -AU - Gadi R -AD - Einstein Institute for Heart and Vascular Health, Albert Einstein Medical Center, - and Jefferson Medical College, PA 19141, United States. ram.gadi@gmail.com -FAU - Amanullah, Aman -AU - Amanullah A -FAU - Figueredo, Vincent M -AU - Figueredo VM -LA - eng -PT - Journal Article -PT - Review -DEP - 20120604 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Cholesterol, HDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 2679MF687A (Niacin) -SB - IM -MH - Age of Onset -MH - Animals -MH - Cardiovascular Diseases/diagnosis/*drug therapy/epidemiology -MH - Cholesterol, HDL/*antagonists & inhibitors/blood -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Niacin/therapeutic use -MH - Risk Factors -MH - *Risk Reduction Behavior -OTO - NOTNLM -OT - Cardiovascular -OT - Coronary artery disease -OT - HDL-C therapeutics -OT - High density lipoprotein (HDL-C) -EDAT- 2012/06/07 06:00 -MHDA- 2014/04/03 06:00 -CRDT- 2012/06/07 06:00 -PHST- 2011/11/01 00:00 [received] -PHST- 2012/03/09 00:00 [revised] -PHST- 2012/05/11 00:00 [accepted] -PHST- 2012/06/07 06:00 [entrez] -PHST- 2012/06/07 06:00 [pubmed] -PHST- 2014/04/03 06:00 [medline] -AID - S0167-5273(12)00666-3 [pii] -AID - 10.1016/j.ijcard.2012.05.052 [doi] -PST - ppublish -SO - Int J Cardiol. 2013 Aug 10;167(3):646-55. doi: 10.1016/j.ijcard.2012.05.052. Epub - 2012 Jun 4. - -PMID- 19862545 -OWN - NLM -STAT- MEDLINE -DCOM- 20100702 -LR - 20250623 -IS - 1432-2099 (Electronic) -IS - 0301-634X (Print) -IS - 0301-634X (Linking) -VI - 49 -IP - 2 -DP - 2010 May -TI - Review and meta-analysis of epidemiological associations between low/moderate - doses of ionizing radiation and circulatory disease risks, and their possible - mechanisms. -PG - 139-53 -LID - 10.1007/s00411-009-0250-z [doi] -AB - Although the link between high doses of ionizing radiation and damage to the - heart and coronary arteries has been well established for some time, the - association between lower-dose exposures and late occurring cardiovascular - disease has only recently begun to emerge, and is still controversial. In this - paper, we extend an earlier systematic review by Little et al. on the - epidemiological evidence for associations between low and moderate doses of - ionizing radiation exposure and late occurring blood circulatory system disease. - Excess relative risks per unit dose in epidemiological studies vary over at least - two orders of magnitude, possibly a result of confounding and effect modification - by well-known (but unobserved) risk factors, and there is statistically - significant (p < 0.00001) heterogeneity between the risks. This heterogeneity is - reduced, but remains significant, if adjustments are made for the effects of - fractionated delivery or if there is stratification by endpoint (cardiovascular - disease vs. stroke, morbidity vs. mortality). One possible biological mechanism - is damage to endothelial cells and subsequent induction of an inflammatory - response, although it seems unlikely that this would extend to low-dose and - low-dose-rate exposure. A recent paper of Little et al. proposed an arguably more - plausible mechanism for fractionated low-dose effects, based on monocyte cell - killing in the intima. Although the predictions of the model are consistent with - the epidemiological data, the experimental predictions made have yet to be - tested. Further epidemiological and biological evidence will allow a firmer - conclusion to be drawn. -FAU - Little, M P -AU - Little MP -AD - Department of Epidemiology and Public Health, Imperial College Faculty of - Medicine, Norfolk Place, London, W2 1PG, UK. mark.little@imperial.ac.uk -FAU - Tawn, E J -AU - Tawn EJ -FAU - Tzoulaki, I -AU - Tzoulaki I -FAU - Wakeford, R -AU - Wakeford R -FAU - Hildebrandt, G -AU - Hildebrandt G -FAU - Paris, F -AU - Paris F -FAU - Tapio, S -AU - Tapio S -FAU - Elliott, P -AU - Elliott P -LA - eng -GR - Z01 CP010131/ImNIH/Intramural NIH HHS/United States -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20091028 -PL - Germany -TA - Radiat Environ Biophys -JT - Radiation and environmental biophysics -JID - 0415677 -SB - IM -MH - Animals -MH - Blood Circulation/radiation effects -MH - Humans -MH - *Radiation Dosage -MH - Radiation Injuries/*epidemiology/etiology/*physiopathology -MH - Risk -MH - Survivors/statistics & numerical data -MH - Vascular Diseases/*epidemiology/*etiology/physiopathology -PMC - PMC3075616 -MID - NIHMS281551 -EDAT- 2009/10/29 06:00 -MHDA- 2010/07/03 06:00 -PMCR- 2011/04/13 -CRDT- 2009/10/29 06:00 -PHST- 2009/05/12 00:00 [received] -PHST- 2009/10/04 00:00 [accepted] -PHST- 2009/10/29 06:00 [entrez] -PHST- 2009/10/29 06:00 [pubmed] -PHST- 2010/07/03 06:00 [medline] -PHST- 2011/04/13 00:00 [pmc-release] -AID - 10.1007/s00411-009-0250-z [doi] -PST - ppublish -SO - Radiat Environ Biophys. 2010 May;49(2):139-53. doi: 10.1007/s00411-009-0250-z. - Epub 2009 Oct 28. - -PMID- 22516738 -OWN - NLM -STAT- MEDLINE -DCOM- 20120917 -LR - 20161125 -IS - 1879-016X (Electronic) -IS - 0163-7258 (Linking) -VI - 135 -IP - 1 -DP - 2012 Jul -TI - Prevention of aortic valve stenosis: a realistic therapeutic target? -PG - 78-93 -LID - 10.1016/j.pharmthera.2012.04.001 [doi] -AB - Aortic valve stenosis (AS) is the most common form of valvular heart disease in - the Western world, affecting ~40% of the population over the age of 80; to date - the only established treatment is valve replacement. However, AS progression - occurs over many years, and is associated from its earliest stages with increased - risk of coronary events. Recent insight into the pathophysiology of AS has - included central roles for angiotensin II, for diminished nitric oxide effect at - the level of valve endothelium and matrix, and for inflammatory activation/redox - stress culminating in activation of pro-calcific stimuli. Despite the presence of - atheroma within the stenotic valve, hyperlipidemia per se does not play a critic - role in the development of obstructive disease. We review emerging options for - pharmacotherapy of AS, including in particular retardation of disease - progression. The various clinical evaluations of lipid-reducing therapy have been - uniformly unsuccessful in slowing AS progression. However, recent studies in - animal models and retrospective evaluations in humans suggest that ACE inhibitors - and/or angiotensin receptor blockers may be effective in this regard. - Furthermore, agents normally utilized to treat osteoporosis also offer promise in - retarding AS. Given the considerable morbidity, mortality and health care costs - associated with AS, such therapeutic developments should be expedited. -CI - Copyright © 2012 Elsevier Inc. All rights reserved. -FAU - Ngo, D T -AU - Ngo DT -AD - University of Adelaide, Basil Hetzel Research Institute, Department of - Cardiology, The Queen Elizabeth Hospital, Australia. -FAU - Sverdlov, A L -AU - Sverdlov AL -FAU - Horowitz, J D -AU - Horowitz JD -LA - eng -PT - Journal Article -PT - Review -DEP - 20120406 -PL - England -TA - Pharmacol Ther -JT - Pharmacology & therapeutics -JID - 7905840 -RN - 0 (Cardiovascular Agents) -RN - 0 (Receptors, Cytoplasmic and Nuclear) -RN - 31C4KY9ESH (Nitric Oxide) -RN - EC 4.6.1.2 (Guanylate Cyclase) -RN - EC 4.6.1.2 (Soluble Guanylyl Cyclase) -SB - IM -MH - Animals -MH - Aortic Valve/*drug effects/metabolism/pathology/physiopathology -MH - Aortic Valve - Stenosis/epidemiology/metabolism/pathology/physiopathology/*prevention & control -MH - Cardiovascular Agents/*therapeutic use -MH - Disease Progression -MH - Guanylate Cyclase/metabolism -MH - Humans -MH - Nitric Oxide/metabolism -MH - Oxidation-Reduction -MH - Oxidative Stress/drug effects -MH - Receptors, Cytoplasmic and Nuclear/metabolism -MH - Renin-Angiotensin System/drug effects -MH - Risk Assessment -MH - Risk Factors -MH - Soluble Guanylyl Cyclase -EDAT- 2012/04/21 06:00 -MHDA- 2012/09/18 06:00 -CRDT- 2012/04/21 06:00 -PHST- 2012/03/15 00:00 [received] -PHST- 2012/03/16 00:00 [accepted] -PHST- 2012/04/21 06:00 [entrez] -PHST- 2012/04/21 06:00 [pubmed] -PHST- 2012/09/18 06:00 [medline] -AID - S0163-7258(12)00067-8 [pii] -AID - 10.1016/j.pharmthera.2012.04.001 [doi] -PST - ppublish -SO - Pharmacol Ther. 2012 Jul;135(1):78-93. doi: 10.1016/j.pharmthera.2012.04.001. - Epub 2012 Apr 6. - -PMID- 16613757 -OWN - NLM -STAT- MEDLINE -DCOM- 20060720 -LR - 20240306 -IS - 1148-5493 (Print) -IS - 1148-5493 (Linking) -VI - 17 -IP - 1 -DP - 2006 Mar -TI - Recent advances in the relationship between obesity, inflammation, and insulin - resistance. -PG - 4-12 -AB - It now appears that, in most obese patients, obesity is associated with a - low-grade inflammation of white adipose tissue (WAT) resulting from chronic - activation of the innate immune system and which can subsequently lead to insulin - resistance, impaired glucose tolerance and even diabetes. WAT is the - physiological site of energy storage as lipids. In addition, it has been more - recently recognized as an active participant in numerous physiological and - pathophysiological processes. In obesity, WAT is characterized by an increased - production and secretion of a wide range of inflammatory molecules including - TNF-alpha and interleukin-6 (IL-6), which may have local effects on WAT - physiology but also systemic effects on other organs. Recent data indicate that - obese WAT is infiltrated by macrophages, which may be a major source of - locally-produced pro-inflammatory cytokines. Interestingly, weight loss is - associated with a reduction in the macrophage infiltration of WAT and an - improvement of the inflammatory profile of gene expression. Several factors - derived not only from adipocytes but also from infiltrated macrophages probably - contribute to the pathogenesis of insulin resistance. Most of them are - overproduced during obesity, including leptin, TNF-alpha, IL-6 and resistin. - Conversely, expression and plasma levels of adiponectin, an insulin-sensitising - effector, are down-regulated during obesity. Leptin could modulate TNF-alpha - production and macrophage activation. TNF-alpha is overproduced in adipose tissue - of several rodent models of obesity and has an important role in the pathogenesis - of insulin resistance in these species. However, its actual involvement in - glucose metabolism disorders in humans remains controversial. IL-6 production by - human adipose tissue increases during obesity. It may induce hepatic CRP - synthesis and may promote the onset of cardiovascular complications. Both - TNF-alpha and IL-6 can alter insulin sensitivity by triggering different key - steps in the insulin signalling pathway. In rodents, resistin can induce insulin - resistance, while its implication in the control of insulin sensitivity is still - a matter of debate in humans. Adiponectin is highly expressed in WAT, and - circulating adiponectin levels are decreased in subjects with obesity-related - insulin resistance, type 2 diabetes and coronary heart disease. Adiponectin - inhibits liver neoglucogenesis and promotes fatty acid oxidation in skeletal - muscle. In addition, adiponectin counteracts the pro-inflammatory effects of - TNF-alpha on the arterial wall and probably protects against the development of - arteriosclerosis. In obesity, the pro-inflammatory effects of cytokines through - intracellular signalling pathways involve the NF-kappaB and JNK systems. Genetic - or pharmacological manipulations of these effectors of the inflammatory response - have been shown to modulate insulin sensitivity in different animal models. In - humans, it has been suggested that the improved glucose tolerance observed in the - presence of thiazolidinediones or statins is likely related to their - anti-inflammatory properties. Thus, it can be considered that obesity corresponds - to a sub-clinical inflammatory condition that promotes the production of - pro-inflammatory factors involved in the pathogenesis of insulin resistance. -FAU - Bastard, Jean-Philippe -AU - Bastard JP -AD - Inserm U680, Faculté de Médecine Pierre et Marie Curie, site Saint-Antoine, - Université Pierre et Marie Curie, Paris 6 et Service de Biochimie et - Hormonologie, Hôpital Tenon, AP-HP, 75970 Paris cedex 20, France. - jean-philippe.bastard@tnn.ap-hop-paris.fr -FAU - Maachi, Mustapha -AU - Maachi M -FAU - Lagathu, Claire -AU - Lagathu C -FAU - Kim, Min Ji -AU - Kim MJ -FAU - Caron, Martine -AU - Caron M -FAU - Vidal, Hubert -AU - Vidal H -FAU - Capeau, Jacqueline -AU - Capeau J -FAU - Feve, Bruno -AU - Feve B -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - France -TA - Eur Cytokine Netw -JT - European cytokine network -JID - 9100879 -RN - 0 (Adiponectin) -RN - 0 (Interleukin-6) -RN - 0 (Leptin) -RN - 0 (Resistin) -RN - 0 (Tumor Necrosis Factor-alpha) -SB - IM -MH - Adiponectin/biosynthesis/blood -MH - Adipose Tissue/*immunology -MH - Diabetes Mellitus, Type 2/*complications/immunology -MH - Humans -MH - Inflammation/complications/immunology -MH - Insulin Resistance/*physiology -MH - Interleukin-6/biosynthesis/blood -MH - Leptin/biosynthesis/blood -MH - *Lipid Metabolism -MH - Macrophages/immunology -MH - Obesity/*complications/immunology -MH - Resistin/biosynthesis/blood -MH - Signal Transduction/physiology -MH - Tumor Necrosis Factor-alpha/biosynthesis -RF - 94 -EDAT- 2006/04/15 09:00 -MHDA- 2006/07/21 09:00 -CRDT- 2006/04/15 09:00 -PHST- 2006/01/26 00:00 [accepted] -PHST- 2006/04/15 09:00 [pubmed] -PHST- 2006/07/21 09:00 [medline] -PHST- 2006/04/15 09:00 [entrez] -PST - ppublish -SO - Eur Cytokine Netw. 2006 Mar;17(1):4-12. - -PMID- 17987382 -OWN - NLM -STAT- MEDLINE -DCOM- 20080819 -LR - 20211020 -IS - 1382-4147 (Print) -IS - 1382-4147 (Linking) -VI - 13 -IP - 3 -DP - 2008 Sep -TI - Pathways involved in the transition from hypertension to hypertrophy to heart - failure. Treatment strategies. -PG - 367-75 -AB - The renin-angiotensin-aldosterone system (RAAS) is critical in regulating - systemic blood pressure, water and electrolyte balance, and pituitary gland - hormones. These physiologies appear to be primarily mediated by the angiotensin - II/AT(1) receptor subtype system. Overstimulation of this system can predispose - cardiovascular disease (CVD) characterized by excessive vasoconstriction, - fibrosis, and cardiac remodeling. If untreated, the patient typically displays a - continuum of pathophysiologic conditions progressing from atherosclerosis to left - ventricle hypertrophy (LVH), coronary thrombosis, myocardial infarcts, with heart - failure as an endpoint. Intervention with antihypertensive therapy is necessary - to inhibit this progression. RAAS blocking drugs appear to be the most effective - approach. Diastolic heart failure patients benefit from treatment with - angiotensin converting enzyme (ACE) inhibitors and angiotensin AT(1) receptor - blockers (ARBs). Elderly CVD patients evidence age-related changes in body - composition that alter the distribution and half-life of medications, thus - presenting special challenges to treatment. The presence of comorbidities such as - diabetes, renal dysfunction, liver insufficiency further complicates any - therapeutic strategy. In addition, noncompliance because of cognitive impairment, - depression, confusion due to the complexity of dose regimens, and lack of an - appropriate social support system can disrupt positive outcome. The present - review discusses the roles of an overactive RAAS and sympathetic nervous system - as primary contributors to CVD. In addition, treatment strategies are discussed, - focusing on middle aged and elderly hypertensive and heart failure patients. -FAU - Wright, John W -AU - Wright JW -AD - Department of Psychology, Washington State University, Pullman, WA 99164-4820, - USA. wrightjw@wsu.edu -FAU - Mizutani, Shigehiko -AU - Mizutani S -FAU - Harding, Joseph W -AU - Harding JW -LA - eng -GR - R01-HL64245-03/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -DEP - 20071107 -PL - United States -TA - Heart Fail Rev -JT - Heart failure reviews -JID - 9612481 -RN - 0 (Antihypertensive Agents) -RN - 0 (Receptor, Angiotensin, Type 1) -SB - IM -MH - Antihypertensive Agents/pharmacology/*therapeutic use -MH - Disease Progression -MH - Heart Failure/*drug therapy/physiopathology -MH - Humans -MH - Hypertension/*drug therapy/physiopathology -MH - Hypertrophy, Left Ventricular/*drug therapy/physiopathology -MH - Models, Biological -MH - Receptor, Angiotensin, Type 1/physiology -MH - Renin-Angiotensin System/drug effects/physiology -MH - Sympathetic Nervous System/drug effects/physiopathology -RF - 77 -EDAT- 2007/11/08 09:00 -MHDA- 2008/08/20 09:00 -CRDT- 2007/11/08 09:00 -PHST- 2007/09/13 00:00 [received] -PHST- 2007/10/16 00:00 [accepted] -PHST- 2007/11/08 09:00 [pubmed] -PHST- 2008/08/20 09:00 [medline] -PHST- 2007/11/08 09:00 [entrez] -AID - 10.1007/s10741-007-9060-z [doi] -PST - ppublish -SO - Heart Fail Rev. 2008 Sep;13(3):367-75. doi: 10.1007/s10741-007-9060-z. Epub 2007 - Nov 7. - -PMID- 21285931 -OWN - NLM -STAT- MEDLINE -DCOM- 20110830 -LR - 20110202 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 59 -IP - 1 -DP - 2011 Feb -TI - Benefits of drug eluting stents versus bare metal stents in ST-elevation - myocardial infarction: a contemporary review. -PG - 49-59 -AB - The efficacy of drug-eluting stents (DES) in reducing the rates of in-stent - restenosis after percutaneous coronary intervention (PCI) compared to bare metal - stents (BMS) in stable coronary artery disease has been well demonstrated. Thus, - the Food and Drug Administration has approved the utilization of DES for stable - coronary disease. However, there is still much debate surrounding the - implantation of DES for patients with ST-segment elevation myocardial infarction - (STEMI) given safety concerns about the possibility of increased rates of stent - thrombosis with DES. The review of the current body of evidence comparing DES - with BMS is consistent with results from previous trials in stable coronary - disease and reveals lower rates of revascularization with DES in STEMI patients. - The ultimate decision regarding the appropriate stent during PCI needs to be - individualized as patients' compliance with dual antiplatelet therapy is - critical. The data suggest that PCI with DES in STEMI patients who adhere to - long-term dual antiplatelet therapy is safe and effective. Randomized trials with - longer-term follow-up are necessary to better elucidate the safety and efficacy - of DES versus BMS in patients with STEMI. -FAU - Bokhoor, P I -AU - Bokhoor PI -AD - Division of Cardiology, David Geffen School of Medicine at University of - California, Los Angeles, CA 90095-171715, USA. -FAU - Lee, M S -AU - Lee MS -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -SB - IM -MH - Drug-Eluting Stents -MH - Humans -MH - Meta-Analysis as Topic -MH - Myocardial Infarction/physiopathology/*surgery -MH - Prosthesis Design -MH - Randomized Controlled Trials as Topic -MH - Registries -MH - *Stents -EDAT- 2011/02/03 06:00 -MHDA- 2011/08/31 06:00 -CRDT- 2011/02/03 06:00 -PHST- 2011/02/03 06:00 [entrez] -PHST- 2011/02/03 06:00 [pubmed] -PHST- 2011/08/31 06:00 [medline] -AID - R05113063 [pii] -PST - ppublish -SO - Minerva Cardioangiol. 2011 Feb;59(1):49-59. - -PMID- 23888731 -OWN - NLM -STAT- MEDLINE -DCOM- 20150813 -LR - 20190923 -IS - 0025-8105 (Print) -IS - 0025-8105 (Linking) -VI - 66 -IP - 5-6 -DP - 2013 May-Jun -TI - [Electrocardiographic specificities in athletes]. -PG - 225-32 -AB - INTRODUCTION: The use of electrocardiogram in athletes as a routine screening - method for diagnosing potentially dangerous cardiovascular diseases is still an - issue of debate. According to the guidelines of the European Society of - Cardiology, the recording of electrocardiogram is necessary in all athletes as a - screening method, whereas the guidelines of the American Heart Association do not - necessitate an electrocardiogram as a screening method and they insist on - detailed personal and family history and clinical examination. CLASSIFICATION OF - ELECTROCARDIOGRAM CHANGES IN ATHLETES: According to the classification of the - European Society of Cardiology, electrocardiogram changes in athletes are divided - into two groups: a) usual (physiological) that are connected with training; b) - unusual (potentially clinically relevant) that are not connected with training. - SUDDEN CARDIAC DEATH IN ATHLETES: The most frequent causes include hypertrophic - cardiomyopathy and congenital coronary artery anomalies, while others may be - found only sporadically at autopsy. Physiological electrocardiogram changes are - frequent in asymptomatic athletes and they do not require further assessment. - They include sinus bradycardia, atrioventricular blocks of I and II - degree--Wenkebach, isolated increased QRS voltage, incomplete right bundle branch - block and early repolarization. Potentially pathological electrocardiogram - changes in athletes are not frequent but they are alarming and they urge further - assessment to diagnose the underlying cardiovascular disease as well as the - prevention of sudden cardiac death. They include: T wave inversion, ST segment - depression, complete right or left bundle branch block, atrial pre-excitation - syndrome-WPW, long QT interval, short QT interval, Brugada like electrocardiogram - finding. CONCLUSION: Introduction of electrocardiogram recording into the - screening protocol in athletes increases the sensitivity of evaluation and may - help to discover asymptomatic cardiovascular diseases that may cause sudden - cardiac death. Special attention and further assessment are required when the - above potentially pathological electrocardiogram changes are found in athletes. -FAU - Mazić, Sanja -AU - Mazić S -AD - Institut za medicinsku fiziologiju, Medicinski fakultet Univerziteta u Beogradu. -FAU - Lazović, Biljana -AU - Lazović B -FAU - Delić, Marina -AU - Delić M -FAU - Stajić, Zoran -AU - Stajić Z -FAU - Mijailović, Zdravko -AU - Mijailović Z -LA - srp -PT - English Abstract -PT - Journal Article -PT - Review -PL - Serbia -TA - Med Pregl -JT - Medicinski pregled -JID - 2985249R -SB - IM -MH - Arrhythmias, Cardiac/diagnosis -MH - *Athletes -MH - Death, Sudden, Cardiac/prevention & control -MH - *Electrocardiography -MH - Heart Diseases/*diagnosis -MH - Humans -MH - Mass Screening -MH - Physical Examination -MH - Sports -EDAT- 2013/07/31 06:00 -MHDA- 2015/08/14 06:00 -CRDT- 2013/07/30 06:00 -PHST- 2013/07/30 06:00 [entrez] -PHST- 2013/07/31 06:00 [pubmed] -PHST- 2015/08/14 06:00 [medline] -AID - 10.2298/mpns1306225m [doi] -PST - ppublish -SO - Med Pregl. 2013 May-Jun;66(5-6):225-32. doi: 10.2298/mpns1306225m. - -PMID- 19466911 -OWN - NLM -STAT- MEDLINE -DCOM- 20100304 -LR - 20171116 -IS - 1744-7666 (Electronic) -IS - 1465-6566 (Linking) -VI - 10 -IP - 9 -DP - 2009 Jun -TI - Angiotensin II receptor blockers in the prevention of atrial fibrillation. -PG - 1395-411 -LID - 10.1517/14656560902973736 [doi] -AB - Atrial fibrillation (AF) is the most common sustained arrhythmia. While - antiarrhythmic agents and electrical cardioversion are highly effective in - restoring sinus rhythm, the results obtained in prevention of recurrences are - disappointing. Recently, angiotensin II has been recognized as a key factor in - atrial structural and electrical remodeling associated with AF. So there are - several potential mechanisms by which inhibition of the - renin-angiotensin-aldosterone system may reduce AF. In this review, we report the - results of studies evaluating the effect of angiotensin II receptor blockers - (ARBs) in various clinical settings (i.e., lone AF, hypertension, high-risk - patients, congestive heart failure, secondary prevention). However, many of these - studies are small and retrospective and have a limited follow-up; moreover, since - AF is related to several causes, chiefly heart diseases, patients with different - characteristics have often been enrolled. Thus, it is not surprising that the - results obtained are frequently conflicting. With these limitations and - considering only the results of larger studies with longer follow-up, ARBs are - effective in preventing AF in patients with congestive heart failure or - hypertension with left ventricular hypertrophy or coronary artery/cerebrovascular - disease. In any case, the use of ARBs is not recommended at present in clinical - practice to prevent AF. -FAU - Barra, Silvia -AU - Barra S -AD - Antonio Cardarelli Hospital, Cardiology Unit, Via Antonio Cardarelli 9, 80128 - Naples, Italy. -FAU - Silvestri, Nunzia -AU - Silvestri N -FAU - Vitagliano, Giancarlo -AU - Vitagliano G -FAU - Madrid, Alfredo -AU - Madrid A -FAU - Gaeta, Giovanni -AU - Gaeta G -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Opin Pharmacother -JT - Expert opinion on pharmacotherapy -JID - 100897346 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Receptor, Angiotensin, Type 1) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/pharmacology/*therapeutic use -MH - Animals -MH - Atrial Fibrillation/physiopathology/*prevention & control -MH - Clinical Trials as Topic/methods -MH - Contraindications -MH - Humans -MH - Receptor, Angiotensin, Type 1/physiology -RF - 92 -EDAT- 2009/05/27 09:00 -MHDA- 2010/03/05 06:00 -CRDT- 2009/05/27 09:00 -PHST- 2009/05/27 09:00 [entrez] -PHST- 2009/05/27 09:00 [pubmed] -PHST- 2010/03/05 06:00 [medline] -AID - 10.1517/14656560902973736 [doi] -PST - ppublish -SO - Expert Opin Pharmacother. 2009 Jun;10(9):1395-411. doi: - 10.1517/14656560902973736. - -PMID- 23579938 -OWN - NLM -STAT- MEDLINE -DCOM- 20150413 -LR - 20211021 -IS - 1535-7414 (Print) -IS - 1930-0573 (Electronic) -IS - 1535-7414 (Linking) -VI - 33 -IP - 1-2 -DP - 2010 -TI - Focus on: The cardiovascular system: what did we learn from the French (Paradox)? -PG - 76-86 -AB - Although heavy alcohol consumption has deleterious effects on heart health, - moderate drinking is thought to have cardioprotective effects, reducing the risk - of coronary artery disease and improving prognosis after a myocardial infarction. - It still is unclear, however, if this effect can be achieved with all types of - alcoholic beverages and results from the alcohol itself, from other compounds - found in alcoholic beverages, or both. For example, the polyphenolic compound - resveratrol, which is found particularly in red wine, can reduce the risk of - atherosclerosis; however, it is not clear if the resveratrol levels present in - wine are sufficient to achieve this result. Alcohol itself contributes to - cardioprotection through several mechanisms. For example, it can improve the - cholesterol profile, increasing the levels of "good" cholesterol and reducing the - levels of "bad" cholesterol. Alcohol also may contribute to blood clot - dissolution and may induce a phenomenon called pre-conditioning, whereby exposure - to moderate alcohol levels (like short bouts of blood supply disruption [i.e., - ischemia]), and result in reduced damage to the heart tissue after subsequent - prolonged ischemia. Finally, the enzyme aldehyde dehydrogenase (ALDH) 2, which is - involved in alcohol metabolism, also may contribute to alcohol-related - cardioprotection by metabolizing other harmful aldehydes that could damage the - heart muscle. -FAU - Mochly-Rosen, Daria -AU - Mochly-Rosen D -AD - Stanford University School of Medicine, Stanford, California. -FAU - Zakhari, Samir -AU - Zakhari S -LA - eng -GR - NIAAA-11147/PHS HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - Alcohol Res Health -JT - Alcohol research & health : the journal of the National Institute on Alcohol - Abuse and Alcoholism -JID - 100900708 -RN - 0 (Antioxidants) -RN - 0 (Stilbenes) -RN - EC 1.2.1.3 (ALDH2 protein, human) -RN - EC 1.2.1.3 (Aldehyde Dehydrogenase) -RN - EC 1.2.1.3 (Aldehyde Dehydrogenase, Mitochondrial) -RN - Q369O8926L (Resveratrol) -SB - IM -CIN - Alcohol Res Health. 33(1-2):161. -MH - Alcohol Drinking/adverse effects/epidemiology/*metabolism -MH - *Alcoholic Beverages/adverse effects -MH - Aldehyde Dehydrogenase/metabolism -MH - Aldehyde Dehydrogenase, Mitochondrial -MH - Animals -MH - Antioxidants/administration & dosage/metabolism -MH - Binge Drinking/epidemiology/metabolism -MH - Cardiovascular Diseases/epidemiology/*metabolism/*prevention & control -MH - Cardiovascular System -MH - Humans -MH - Resveratrol -MH - Stilbenes/administration & dosage/metabolism -MH - Wine/adverse effects -PMC - PMC3887499 -EDAT- 2010/01/01 00:00 -MHDA- 2015/04/14 06:00 -PMCR- 2010/01/01 -CRDT- 2013/04/13 06:00 -PHST- 2013/04/13 06:00 [entrez] -PHST- 2010/01/01 00:00 [pubmed] -PHST- 2015/04/14 06:00 [medline] -PHST- 2010/01/01 00:00 [pmc-release] -AID - arh-33-1_2-76 [pii] -PST - ppublish -SO - Alcohol Res Health. 2010;33(1-2):76-86. - -PMID- 17981771 -OWN - NLM -STAT- MEDLINE -DCOM- 20071211 -LR - 20250529 -IS - 1093-9946 (Print) -IS - 1093-4715 (Electronic) -IS - 1093-4715 (Linking) -VI - 13 -DP - 2008 Jan 1 -TI - Mechanisms of chronic rejection in cardiothoracic transplantation. -PG - 2980-8 -AB - Despite significant improvements in early post-transplantation survival rates, - long-term patient and graft survival have remained poor, due in large part to the - vexing problem of chronic allograft rejection. Attempts to combat this problem - with intensification of immunosuppression have led to concomitant increases in - the rates of fatal malignancies and infections. In cardiac transplantation, - chronic rejection is manifested primarily by a disease entity known as cardiac - allograft vasculopathy, an occlusive narrowing of the coronary vessels. In lung - transplantation, chronic rejection is typified by obliterative bronchiolitis, an - airflow limiting narrowing of the bronchioles. From an immunologic standpoint, - chronic rejection is believed to be the end result of repeated immune and - non-immune insults to the graft. This review examines the pathophysiology of - heart and lung chronic, with emphasis on both immune and non-immune causes. -FAU - Weiss, Matthew J -AU - Weiss MJ -AD - Transplantation Biology Research Center, Massachusetts General Hospital and - Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA. -FAU - Madsen, Joren C -AU - Madsen JC -FAU - Rosengard, Bruce R -AU - Rosengard BR -FAU - Allan, James S -AU - Allan JS -LA - eng -GR - R01HL67110/HL/NHLBI NIH HHS/United States -GR - P01HL8646/HL/NHLBI NIH HHS/United States -GR - R01HL054211/HL/NHLBI NIH HHS/United States -GR - R01HL071932/HL/NHLBI NIH HHS/United States -GR - R01 HL071932/HL/NHLBI NIH HHS/United States -GR - R01 HL067110/HL/NHLBI NIH HHS/United States -GR - R01 HL054211/HL/NHLBI NIH HHS/United States -GR - U19 AI066705/AI/NIAID NIH HHS/United States -GR - U19AI066705/AI/NIAID NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20080101 -PL - United States -TA - Front Biosci -JT - Frontiers in bioscience : a journal and virtual library -JID - 9709506 -RN - 0 (HLA Antigens) -RN - 0 (Immunosuppressive Agents) -SB - IM -MH - Autoimmunity -MH - Brain Death -MH - Bronchiolitis Obliterans/metabolism -MH - Cell Transplantation -MH - Gastroesophageal Reflux/*complications/pathology -MH - HLA Antigens/*chemistry -MH - Heart Transplantation/methods -MH - Humans -MH - *Immunity, Innate -MH - Immunosuppressive Agents/therapeutic use -MH - Lung Transplantation/methods -MH - Organ Transplantation -MH - Stem Cells/cytology/metabolism -MH - Tissue and Organ Procurement -PMC - PMC2867599 -MID - NIHMS193503 -EDAT- 2007/11/06 09:00 -MHDA- 2007/12/12 09:00 -PMCR- 2010/05/11 -CRDT- 2007/11/06 09:00 -PHST- 2007/11/06 09:00 [pubmed] -PHST- 2007/12/12 09:00 [medline] -PHST- 2007/11/06 09:00 [entrez] -PHST- 2010/05/11 00:00 [pmc-release] -AID - 2903 [pii] -AID - 10.2741/2903 [doi] -PST - epublish -SO - Front Biosci. 2008 Jan 1;13:2980-8. doi: 10.2741/2903. - -PMID- 17579248 -OWN - NLM -STAT- MEDLINE -DCOM- 20070824 -LR - 20161124 -IS - 0231-5882 (Print) -IS - 0231-5882 (Linking) -VI - 26 -IP - 1 -DP - 2007 Mar -TI - Intrinsic defensive mechanisms in the heart: a potential novel approach to - cardiac protection against ischemic injury. -PG - 3-13 -AB - Despite recent advances in pharmacotherapy of coronary artery disease and - interventional cardiology, the management of myocardial ischemia still remains a - major challenge for basic scientists and clinical cardiologists. An urgent need - to combat ischemic heart disease, its forms, such as infarction, and - complications including sudden cardiac death led to the development of an - alternative strategy of myocardial protection based on the exploitation of the - heart's own intrinsic protective mechanisms. A new concept relies on the evidence - that the heart is able to protect itself by way of adaptation, either short-term - or long-term, to transient episodes of stress (e.g., ischemia, hypoxia, free - oxygen radicals, heat stress, etc.) preceding sustained ischemia. Preconditioning - by brief episodes of ischemia (ischemic preconditioning, IP) represents the most - powerful cardioprotective phenomenon. Apart from the short-lasting protection - afforded by classical IP or its delayed ("second window") phase, adaptation to - long-lasting physiological stimuli or pathological processes is also known to - increase myocardial resistance to ischemic injury. Although molecular mechanisms - of cardiac adaptation conferring a higher ischemic tolerance still remain not - sufficiently elucidated, multiple cascades of intracellular signalization are - suggested to be involved in this process. Experimental studies led to the - observations that pharmacological modulations at different levels of signal - transduction might mimic protective effects of the adaptive phenomena and thus - provide a safer way of inducing cardioprotection in humans. -FAU - Ravingerová, T -AU - Ravingerová T -AD - Institute for Heart Research, Centre of Excellence for Cardiovascular Research of - Slovak Academy of Sciences, Bratislava, Slovakia. usrdravi@savba.sk -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Slovakia -TA - Gen Physiol Biophys -JT - General physiology and biophysics -JID - 8400604 -RN - 0 (Free Radicals) -SB - IM -MH - Death, Sudden, Cardiac/pathology/prevention & control -MH - Free Radicals/metabolism -MH - Heat Stress Disorders/pathology/prevention & control -MH - Humans -MH - Hypoxia/pathology/prevention & control -MH - Ischemic Preconditioning, Myocardial/*methods -MH - Myocardial Infarction/pathology/prevention & control -MH - Myocardial Ischemia/*complications/pathology/*prevention & control -MH - Signal Transduction/physiology -MH - Stress, Physiological/pathology/*prevention & control -MH - Time Factors -RF - 125 -EDAT- 2007/06/21 09:00 -MHDA- 2007/08/25 09:00 -CRDT- 2007/06/21 09:00 -PHST- 2007/06/21 09:00 [pubmed] -PHST- 2007/08/25 09:00 [medline] -PHST- 2007/06/21 09:00 [entrez] -PST - ppublish -SO - Gen Physiol Biophys. 2007 Mar;26(1):3-13. - -PMID- 20823718 -OWN - NLM -STAT- MEDLINE -DCOM- 20110103 -LR - 20231213 -IS - 1473-5598 (Electronic) -IS - 0263-6352 (Linking) -VI - 28 Suppl 1 -DP - 2010 Sep -TI - Nitric oxide pathway in hypertrophied heart: new therapeutic uses of nitric oxide - donors. -PG - S56-61 -LID - 10.1097/01.hjh.0000388496.66330.b8 [doi] -AB - Left ventricular hypertrophy (LVH) is regarded as a complication common to a - number of cardiovascular diseases, including hypertension, myocardial infarction - and ischaemia associated with coronary artery disease. Initially LVH is a - compensatory mechanism, but in the long term cardiac hypertrophy predisposes - individuals to heart failure, myocardial infarction and sudden death. Alteration - of the nitric oxide (NO) pathway is believed to play an important role in the - haemodynamically overloaded heart and pathological cardiac remodelling. Although - re-establishment of the physiological NO pathway could be considered an important - therapeutic target, the use of conventional nitrates is limited in the clinical - setting by the development of tissue resistance and tolerance and by the shortage - of large-scale clinical trials unequivocally confirming the beneficial impact of - NO donors on cardiovascular morbidity and mortality. The aim of this review is to - present current therapeutic options for dealing with changes in the L-arginine-NO - pathway. The most promising therapeutic approach is represented by a new neutral - sugar organic nitrate, LA-419, the thiol group of which seems to protect NO from - degradation, thereby increasing its bioavailability. In a model of aortic - stenosis-induced pressure overload, LA-419 has been found to restore the complete - NO signalling cascade and reduce left ventricular remodelling, but without - restoring the original pressure gradient, indicating a possible direct - antiproliferative effect. Future studies are needed to confirm this therapeutic - benefit in other animal models of hypertension and in the clinical setting. -FAU - Ruiz-Hurtado, Gema -AU - Ruiz-Hurtado G -AD - Departamento de Farmacología, Facultad de Medicina, Universidad Complutense, - Madrid, Spain. -FAU - Delgado, Carmen -AU - Delgado C -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Netherlands -TA - J Hypertens -JT - Journal of hypertension -JID - 8306882 -RN - 0 (Nitric Oxide Donors) -RN - 0 (Biopterins) -RN - 31C4KY9ESH (Nitric Oxide) -RN - 94ZLA3W45F (Arginine) -RN - EC 1.14.13.39 (Nitric Oxide Synthase) -RN - EGX657432I (sapropterin) -RN - H2D2X058MU (Cyclic GMP) -SB - IM -MH - Arginine/therapeutic use -MH - Biopterins/analogs & derivatives/therapeutic use -MH - Cardiomegaly/drug therapy/enzymology/*metabolism -MH - Cyclic GMP/metabolism -MH - Humans -MH - Nitric Oxide/*metabolism -MH - Nitric Oxide Donors/*therapeutic use -MH - Nitric Oxide Synthase/metabolism -EDAT- 2010/09/18 06:00 -MHDA- 2011/01/05 06:00 -CRDT- 2010/09/09 06:00 -PHST- 2010/09/09 06:00 [entrez] -PHST- 2010/09/18 06:00 [pubmed] -PHST- 2011/01/05 06:00 [medline] -AID - 10.1097/01.hjh.0000388496.66330.b8 [doi] -PST - ppublish -SO - J Hypertens. 2010 Sep;28 Suppl 1:S56-61. doi: 10.1097/01.hjh.0000388496.66330.b8. - -PMID- 20380338 -OWN - NLM -STAT- MEDLINE -DCOM- 20100521 -LR - 20101118 -IS - 1827-6806 (Print) -IS - 1827-6806 (Linking) -VI - 11 -IP - 1 -DP - 2010 Jan -TI - [Origin and evolution of vasovagal syncope]. -PG - 20-7 -AB - Vasovagal syncope (VVS) is characterized by sudden hypotension and bradycardia, - due to inhibition of the sympathetic system and activation of the vagal system, - respectively. Major lines of evidence suggest that classical (emotional and - orthostatic) VVS is not a disease, but a characteristic of the individual. It is, - therefore, interesting to investigate the factors that can explain its origin and - evolution and, to this purpose, we investigated the available literature data on - the vasovagal reflex in animals, including humans. We found two processes in - vertebrates, which appear relevant to the investigation of VVS evolution: fear - and threat bradycardia in animals and vasovagal reflex during hemorrhagic shock, - both in animals and humans. The trigger of the latter is thoracic hypovolemia, - the same of the vasovagal reflex occurring in humans during orthostatic stress - (prolonged standing, tilt testing). During thoracic hypovolemia, the vasovagal - reflex in humans seems to share physiological mechanisms similar to those - observed in other mammals, that is an activation of the vagal system and an - inhibition of the sympathetic system, preceded by an activation of the same - system. Even emotional VVS in humans seems to share physiological mechanisms - similar to those observed in other vertebrates during fear/threat bradycardia. - Therefore, the vasovagal reflex appears to be predisposed in humans and other - vertebrates with the same mechanisms and this may indicate a common evolutionary - root. If the vasovagal reflex persisted for millions of years along the - vertebrates evolutionary history, we can reasonably assume that it has (or it - maybe had in the past) a function. Also, since this reflex is sporadically - displayed, a role as a "defense mechanism" appears likely. The most likely - hypothesis is a defense mechanism of the heart during stressful and possible - dangerous heart conditions. The slowing of heart rate induced by the vasovagal - reflex may constitute a beneficial break of cardiac pump (thereby reducing - myocardial oxygen consumption) and permit better diastolic filling and coronary - perfusion. -FAU - Alboni, Paolo -AU - Alboni P -AD - Divisione di Cardiologia, Ospedale Civile, Cento, FE. p.alboni@ausl.fe.it -FAU - Alboni, Marco -AU - Alboni M -FAU - Bertorelle, Giorgio -AU - Bertorelle G -LA - ita -PT - English Abstract -PT - Journal Article -PT - Review -TT - Origine ed evoluzione della sincope vasovagale. -PL - Italy -TA - G Ital Cardiol (Rome) -JT - Giornale italiano di cardiologia (2006) -JID - 101263411 -SB - IM -MH - Algorithms -MH - Animals -MH - *Biological Evolution -MH - Bradycardia/*physiopathology -MH - *Fear -MH - Humans -MH - Hypotension/physiopathology -MH - Hypotension, Orthostatic/*physiopathology -MH - Hypovolemia/physiopathology -MH - Shock, Hemorrhagic/*physiopathology -MH - Sympathetic Nervous System/physiopathology -MH - Syncope, Vasovagal/etiology/*physiopathology -MH - Vagus Nerve/*physiopathology -RF - 72 -EDAT- 2010/04/13 06:00 -MHDA- 2010/05/22 06:00 -CRDT- 2010/04/13 06:00 -PHST- 2010/04/13 06:00 [entrez] -PHST- 2010/04/13 06:00 [pubmed] -PHST- 2010/05/22 06:00 [medline] -PST - ppublish -SO - G Ital Cardiol (Rome). 2010 Jan;11(1):20-7. - -PMID- 22101013 -OWN - NLM -STAT- MEDLINE -DCOM- 20120510 -LR - 20120113 -IS - 1873-3913 (Electronic) -IS - 0898-6568 (Linking) -VI - 24 -IP - 3 -DP - 2012 Mar -TI - Preconditioning the hyperlipidemic myocardium: fact or fantasy? -PG - 589-95 -LID - 10.1016/j.cellsig.2011.11.003 [doi] -AB - Ischemic heart disease is a leading cause of death worldwide. Myocardial ischemia - results in reduced coronary flow, followed by diminished oxygen and nutrient - supply to the heart. Reperfusion to an ischemic myocardium often augments the - ischemic damage, known as ischemia-reperfusion (I/R) injury. Number of studies - demonstrated that the hyperlipidemic myocardium is rather sensitive and more - vulnerable to I/R-induced myocardial injury. Repeated brief ischemia and - reperfusion cycles, termed as ischemic preconditioning, given before a sustained - ischemia is known to reduce myocardial damage occur as a result of I/R. A - plethora of evidence supports the fact that preconditioning is one of the - promising interventional strategies having an ability to limit I/R-induced - myocardial injury. Despite this fact, the preconditioning-mediated - cardioprotection is blunted in chronic hyperlipidemic condition. This suggests - that preconditioning is moderately a 'healthy heart protective phenomenon'. The - mechanisms by which chronic hyperlipidemia abrogates cardioprotective effects of - preconditioning are uncertain and are not completely understood. The impaired - opening of mitochondrial-K(ATP) channels, eNOS uncoupling and excessive - generation of superoxides in the hyperlipidemic myocardium could play a role in - attenuating preconditioning-mediated myocardial protection against I/R injury. - Moreover, hyperlipidemia-induced loss of cardioprotective effect of - preconditioning is associated with redistribution of both sarcolemmal and - mitochondrial Connexin 43. We addressed, in this review, the potential mechanisms - involved in hyperlipidemia-induced impairment of myocardial preconditioning. - Additionally, novel pharmacologic interventions to attenuate - hyperlipidemia-associated exaggerated I/R-induced myocardial injury have been - discussed. -CI - Copyright © 2011 Elsevier Inc. All rights reserved. -FAU - Balakumar, Pitchai -AU - Balakumar P -AD - Cardiovascular Pharmacology Division, Department of Pharmacology, Institute of - Pharmacy, Rajendra Institute of Technology and Sciences (RITS), Sirsa, India. - pbala2006@gmail.com -FAU - Babbar, Lalita -AU - Babbar L -LA - eng -PT - Journal Article -PT - Review -DEP - 20111109 -PL - England -TA - Cell Signal -JT - Cellular signalling -JID - 8904683 -RN - 0 (Connexin 43) -RN - 0 (Potassium Channels) -RN - 0 (mitochondrial K(ATP) channel) -RN - EC 1.14.13.39 (Nitric Oxide Synthase Type III) -SB - IM -MH - Animals -MH - Connexin 43/metabolism -MH - Humans -MH - Hyperlipidemias/complications/*pathology -MH - *Ischemic Preconditioning, Myocardial -MH - Myocardial Reperfusion Injury/complications/metabolism/pathology -MH - Myocardium/*pathology -MH - Nitric Oxide Synthase Type III/metabolism -MH - Potassium Channels/metabolism -EDAT- 2011/11/22 06:00 -MHDA- 2012/05/11 06:00 -CRDT- 2011/11/22 06:00 -PHST- 2011/10/19 00:00 [received] -PHST- 2011/11/02 00:00 [accepted] -PHST- 2011/11/22 06:00 [entrez] -PHST- 2011/11/22 06:00 [pubmed] -PHST- 2012/05/11 06:00 [medline] -AID - S0898-6568(11)00344-5 [pii] -AID - 10.1016/j.cellsig.2011.11.003 [doi] -PST - ppublish -SO - Cell Signal. 2012 Mar;24(3):589-95. doi: 10.1016/j.cellsig.2011.11.003. Epub 2011 - Nov 9. - -PMID- 22005193 -OWN - NLM -STAT- MEDLINE -DCOM- 20111229 -LR - 20220311 -IS - 0065-2326 (Print) -IS - 0065-2326 (Linking) -VI - 46 -DP - 2011 -TI - Cardiovascular disorders associated with obstructive sleep apnea. -PG - 197-266 -LID - 10.1159/000325110 [doi] -AB - Epidemiological, longitudinal and therapeutic studies have produced convincing - evidence that obstructive sleep apnea (OSA) is associated with an increased risk - of cardiovascular morbidity and mortality. The strongest evidence supports an - independent causal link between OSA and arterial hypertension. OSA may be - independently associated with an increased risk for ischemic heart disease, - stroke, arrhythmias and mortality. It remains to be determined whether OSA is an - independent cause of congestive heart failure and pulmonary hypertension. - Confounders and methodological biases are the main reasons for the lack of - definitive conclusions in causality studies. Longitudinal studies, adequately - powered randomized controlled studies and therapeutic studies involving - well-defined participants are all needed to definitively answer the questions - surrounding the relationship between OSA and clinical cardiovascular outcomes, - comorbidities and intermediate pathogenic mechanisms. OSA is a modifiable risk - factor: continuous positive airway pressure administration, the gold standard - treatment of OSA, may reduce the early signs of endothelial dysfunction and - atherosclerosis, and improve cardiovascular outcomes, such as the mortality - related to cardiovascular events, blood pressure, nonfatal coronary events and - cardiac function in heart failure patients. However, cardiac patients may not - display the typical signs and symptoms of OSA, such as an excessive body mass - index and sleepiness. This fact, and the cardiovascular risk associated with OSA, - underlines the need for collaborative guidelines to define a diagnostic strategy - specifically oriented toward the evaluation of OSA in cardiovascular patients. -CI - Copyright © 2011 S. Karger AG, Basel. -LA - eng -PT - Journal Article -PT - Review -DEP - 20111013 -PL - Switzerland -TA - Adv Cardiol -JT - Advances in cardiology -JID - 0270063 -SB - IM -MH - Adult -MH - Cardiovascular Diseases/*etiology/mortality/physiopathology -MH - Continuous Positive Airway Pressure -MH - Humans -MH - Risk Factors -MH - Sleep Apnea, Obstructive/*complications/mortality/physiopathology/therapy -EDAT- 2011/10/19 06:00 -MHDA- 2011/12/30 06:00 -CRDT- 2011/10/19 06:00 -PHST- 2011/10/19 06:00 [entrez] -PHST- 2011/10/19 06:00 [pubmed] -PHST- 2011/12/30 06:00 [medline] -AID - 000325110 [pii] -AID - 10.1159/000325110 [doi] -PST - ppublish -SO - Adv Cardiol. 2011;46:197-266. doi: 10.1159/000325110. Epub 2011 Oct 13. - -PMID- 17981557 -OWN - NLM -STAT- MEDLINE -DCOM- 20071211 -LR - 20190902 -IS - 1093-9946 (Print) -IS - 1093-4715 (Linking) -VI - 13 -DP - 2008 Jan 1 -TI - Effects of exercise training upon endothelial function in patients with - cardiovascular disease. -PG - 424-32 -AB - Preservation of normal endothelial function depends on the bioavailability of - nitric oxide (NO). In addition, accumulating evidence suggests that bone - marrow-derived circulating progenitor cells (CPCs) are required to maintain the - integrity of the vasculature. However, in patients with cardiovascular disease - (CVD), the impairment of NO production in conjunction with excessive oxidative - stress, results in a decline in NO bioavailability, promotes the loss of - endothelial cells by apoptosis and, therefore, results in endothelial - dysfunction. Moreover, functional alteration of CPCs might contribute to an - impaired endogenous regenerative capacity and lead to further deterioration of - vasomotion in different vascular beds in CVD. However, exercise training (ET) has - assumed a role in cardiac rehabilitation in CVD since it reduces morbidity and - mortality. This has been partially attributed to ET-mediated improvement of - endothelial function. At the molecular levels, accumulating evidence suggests - that regular physical activity restores the balance between NO production and NO - inactivation by ROS. Moreover, ET might have the potential to restore the - regenerative capacity of CPCs in CVD. Given the prognostic value of endothelial - function further studies are necessary to elucidate whether the ET-induced - correction of vasomotion is the key mechanism responsible for the decline in - mortality in patients with CVD. -FAU - Linke, Axel -AU - Linke A -AD - University of Leipzig, Heart Center, Department of Cardiology, Leipzig, Germany. - linkea@medizin.uni-leipzig.de -FAU - Erbs, Sandra -AU - Erbs S -FAU - Hambrecht, Rainer -AU - Hambrecht R -LA - eng -PT - Journal Article -PT - Review -DEP - 20080101 -PL - United States -TA - Front Biosci -JT - Frontiers in bioscience : a journal and virtual library -JID - 9709506 -RN - 0 (Reactive Oxygen Species) -RN - 31C4KY9ESH (Nitric Oxide) -SB - IM -MH - Animals -MH - Apoptosis -MH - Atherosclerosis/pathology -MH - Cardiovascular Diseases/*pathology/*therapy -MH - Coronary Circulation -MH - Endothelium, Vascular/*metabolism/*pathology -MH - *Exercise -MH - Homeostasis -MH - Humans -MH - Models, Biological -MH - Nitric Oxide/metabolism -MH - Prognosis -MH - Reactive Oxygen Species/metabolism -RF - 66 -EDAT- 2007/11/06 09:00 -MHDA- 2007/12/12 09:00 -CRDT- 2007/11/06 09:00 -PHST- 2007/11/06 09:00 [pubmed] -PHST- 2007/12/12 09:00 [medline] -PHST- 2007/11/06 09:00 [entrez] -AID - 2689 [pii] -AID - 10.2741/2689 [doi] -PST - epublish -SO - Front Biosci. 2008 Jan 1;13:424-32. doi: 10.2741/2689. - -PMID- 21093451 -OWN - NLM -STAT- MEDLINE -DCOM- 20110803 -LR - 20250529 -IS - 1095-8584 (Electronic) -IS - 0022-2828 (Print) -IS - 0022-2828 (Linking) -VI - 50 -IP - 5 -DP - 2011 May -TI - Cardiac gene therapy with SERCA2a: from bench to bedside. -PG - 803-12 -LID - 10.1016/j.yjmcc.2010.11.011 [doi] -AB - While progress in conventional treatments is making steady and incremental gains - to reduce mortality associated with heart failure, there remains a need to - explore potentially new therapeutic approaches. Heart failure induced by - different etiologies such as coronary artery disease, hypertension, diabetes, - infection, or inflammation results generally in calcium cycling dysregulation at - the myocyte level. Recent advances in understanding of the molecular basis of - these calcium cycling abnormalities, together with the evolution of increasingly - efficient gene transfer technology, have placed heart failure within reach of - gene-based therapy. Furthermore, the recent successful completion of a phase 2 - trial targeting the sarcoplasmic reticulum calcium pump (SERCA2a) ushers in a new - era for gene therapy for the treatment of heart failure. This article is part of - a Special Section entitled "Special Section: Cardiovascular Gene Therapy". -CI - Copyright © 2010 Elsevier Ltd. All rights reserved. -FAU - Gwathmey, Judith K -AU - Gwathmey JK -AD - Gwathmey Inc, Cambridge, MA 2038, USA. roger.hajjar@mssm.edu -FAU - Yerevanian, Alexan I -AU - Yerevanian AI -FAU - Hajjar, Roger J -AU - Hajjar RJ -LA - eng -GR - R44 HL068354/HL/NHLBI NIH HHS/United States -GR - R01 HL078731/HL/NHLBI NIH HHS/United States -GR - HL093183/HL/NHLBI NIH HHS/United States -GR - HL100396/HL/NHLBI NIH HHS/United States -GR - R01 HL080498/HL/NHLBI NIH HHS/United States -GR - HL080498/HL/NHLBI NIH HHS/United States -GR - P20 HL100396/HL/NHLBI NIH HHS/United States -GR - R01 HL083156/HL/NHLBI NIH HHS/United States -GR - R01 HL093183/HL/NHLBI NIH HHS/United States -GR - R01 HL071763/HL/NHLBI NIH HHS/United States -GR - HL088434/HL/NHLBI NIH HHS/United States -GR - R01 HL088434/HL/NHLBI NIH HHS/United States -GR - HL071763/HL/NHLBI NIH HHS/United States -GR - HL083156/HL/NHLBI NIH HHS/United States -GR - R44HL068354/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -DEP - 20101118 -PL - England -TA - J Mol Cell Cardiol -JT - Journal of molecular and cellular cardiology -JID - 0262322 -RN - EC 3.6.3.8 (Sarcoplasmic Reticulum Calcium-Transporting ATPases) -SB - IM -MH - Animals -MH - Genetic Therapy/*methods -MH - Heart Failure/therapy -MH - Humans -MH - Models, Biological -MH - Sarcoplasmic Reticulum Calcium-Transporting ATPases/*genetics -PMC - PMC3075330 -MID - NIHMS254057 -EDAT- 2010/11/26 06:00 -MHDA- 2011/08/04 06:00 -PMCR- 2012/05/01 -CRDT- 2010/11/25 06:00 -PHST- 2010/10/16 00:00 [received] -PHST- 2010/10/27 00:00 [revised] -PHST- 2010/11/10 00:00 [accepted] -PHST- 2010/11/25 06:00 [entrez] -PHST- 2010/11/26 06:00 [pubmed] -PHST- 2011/08/04 06:00 [medline] -PHST- 2012/05/01 00:00 [pmc-release] -AID - S0022-2828(10)00443-8 [pii] -AID - 10.1016/j.yjmcc.2010.11.011 [doi] -PST - ppublish -SO - J Mol Cell Cardiol. 2011 May;50(5):803-12. doi: 10.1016/j.yjmcc.2010.11.011. Epub - 2010 Nov 18. - -PMID- 21235751 -OWN - NLM -STAT- MEDLINE -DCOM- 20110404 -LR - 20240117 -IS - 1532-429X (Electronic) -IS - 1097-6647 (Print) -IS - 1097-6647 (Linking) -VI - 13 -IP - 1 -DP - 2011 Jan 14 -TI - Comprehensive 4D velocity mapping of the heart and great vessels by - cardiovascular magnetic resonance. -PG - 7 -LID - 10.1186/1532-429X-13-7 [doi] -AB - BACKGROUND: Phase contrast cardiovascular magnetic resonance (CMR) is able to - measure all three directional components of the velocities of blood flow relative - to the three spatial dimensions and the time course of the heart cycle. In this - article, methods used for the acquisition, visualization, and quantification of - such datasets are reviewed and illustrated. METHODS: Currently, the acquisition - of 3D cine (4D) phase contrast velocity data, synchronized relative to both - cardiac and respiratory movements takes about ten minutes or more, even when - using parallel imaging and optimized pulse sequence design. The large resulting - datasets need appropriate post processing for the visualization of - multidirectional flow, for example as vector fields, pathlines or streamlines, or - for retrospective volumetric quantification. APPLICATIONS: Multidirectional - velocity acquisitions have provided 3D visualization of large scale flow features - of the healthy heart and great vessels, and have shown altered patterns of flow - in abnormal chambers and vessels. Clinically relevant examples include retrograde - streams in atheromatous descending aortas as potential thrombo-embolic pathways - in patients with cryptogenic stroke and marked variations of flow visualized in - common aortic pathologies. Compared to standard clinical tools, 4D velocity - mapping offers the potential for retrospective quantification of flow and other - hemodynamic parameters. CONCLUSIONS: Multidirectional, 3D cine velocity - acquisitions are contributing to the understanding of normal and pathologically - altered blood flow features. Although more rapid and user-friendly strategies for - acquisition and analysis may be needed before 4D velocity acquisitions come to be - adopted in routine clinical CMR, their capacity to measure multidirectional flows - throughout a study volume has contributed novel insights into cardiovascular - fluid dynamics in health and disease. -FAU - Markl, Michael -AU - Markl M -AD - Department of Radiology, Medical Physics, University Hospital Freiburg, Germany. - michael.markl@uniklinik-freiburg.de -FAU - Kilner, Philip J -AU - Kilner PJ -FAU - Ebbers, Tino -AU - Ebbers T -LA - eng -GR - British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110114 -PL - England -TA - J Cardiovasc Magn Reson -JT - Journal of cardiovascular magnetic resonance : official journal of the Society - for Cardiovascular Magnetic Resonance -JID - 9815616 -SB - IM -MH - Blood Flow Velocity -MH - Blood Vessels/*physiopathology -MH - Cardiovascular Diseases/*diagnosis/physiopathology -MH - *Coronary Circulation -MH - Heart/*physiopathology -MH - Humans -MH - *Image Interpretation, Computer-Assisted -MH - *Imaging, Three-Dimensional -MH - *Magnetic Resonance Imaging, Cine -MH - Predictive Value of Tests -MH - Regional Blood Flow -MH - Respiratory Mechanics -MH - Time Factors -PMC - PMC3025879 -EDAT- 2011/01/18 06:00 -MHDA- 2011/04/05 06:00 -PMCR- 2011/01/14 -CRDT- 2011/01/18 06:00 -PHST- 2010/07/03 00:00 [received] -PHST- 2011/01/14 00:00 [accepted] -PHST- 2011/01/18 06:00 [entrez] -PHST- 2011/01/18 06:00 [pubmed] -PHST- 2011/04/05 06:00 [medline] -PHST- 2011/01/14 00:00 [pmc-release] -AID - S1097-6647(23)01362-5 [pii] -AID - 1532-429X-13-7 [pii] -AID - 10.1186/1532-429X-13-7 [doi] -PST - epublish -SO - J Cardiovasc Magn Reson. 2011 Jan 14;13(1):7. doi: 10.1186/1532-429X-13-7. - -PMID- 19694215 -OWN - NLM -STAT- MEDLINE -DCOM- 20090917 -LR - 20170306 -VI - 119 -IP - 6 -DP - 2009 Jun -TI - Noninvasive positive pressure ventilation: effect on mortality in acute - cardiogenic pulmonary edema: a pragmatic meta-analysis. -PG - 349-53 -AB - INTRODUCTION: In contrast to a series of recent meta-analyses (MAs), the 3CPO - (Three Interventions in Cardiogenic Pulmonary Oedema) randomized controlled trial - (RCT) reported in 2008 did not find a significant mortality benefit of - noninvasive positive pressure ventilation (NPPV) in acute cardiogenic pulmonary - edema (ACPE). OBJECTIVES: This paper combines data collected in the 3CPO trial - together with data from recent MAs and calculates a revised risk ratio for NPPV - in ACPE. Reasons for the discrepancy in mortality estimates are identified and - discussed through contrasting the methodology and results of the 3CPO trial with - previous RCTs. PATIENTS AND METHODS: Patients included adults with ACPE secondary - to a variety of insults such as hypertension, acute coronary syndromes, dietary - indiscretion, arrhythmias and valvular lesions and assessed by clinical - parameters (respiratory rate, crackles, oxygen saturation) and chest radiograph. - Data was collected from MAs published after 2005 and their respective RCTs. As - opinions regarding RCTs worthy of inclusion in the analyses were varied, 3 sets - of RCTs were combined with the 3CPO data. The first set of data duplicated the - RCTs chosen in the Cochrane; the second set, a comprehensive set, included all - RCTs cited in any of the MAs reviewed; and the third set, a high quality RCT set, - assessed data from only those RCTs included in at least 4 out of the 5 MAs - reviewed. Data were analyzed with both fixed and variable effect modes using - Revman software. RESULTS: All combinations of RCTs and modes of analysis predict - a significant mortality benefit. The combined data predicts a risk ratio for - mortality using NPPV of 0.75 (95% CI: 0.61-0.92). CONCLUSIONS: An analysis of the - existing RCT data, inclusive of the 3CPO trial, predicts a continued and - significant mortality benefit of NPPV in ACPE. -FAU - Potts, Jayson Mathew -AU - Potts JM -AD - Department of Internal Medicine Residency Training Program, McMaster University, - Hamilton, Ontario, Canada. jayson.potts@medportal.ca -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Review -PL - Poland -TA - Pol Arch Med Wewn -JT - Polskie Archiwum Medycyny Wewnetrznej -JID - 0401225 -SB - IM -MH - Acute Disease -MH - Adult -MH - Aged -MH - Confidence Intervals -MH - Continuous Positive Airway Pressure/*statistics & numerical data -MH - Heart Failure/complications/*mortality/*therapy -MH - Humans -MH - Middle Aged -MH - Pulmonary Edema/etiology/*mortality/*therapy -MH - Randomized Controlled Trials as Topic/*methods -MH - Survival Analysis -RF - 8 -EDAT- 2009/08/22 09:00 -MHDA- 2009/09/18 06:00 -CRDT- 2009/08/22 09:00 -PHST- 2009/08/22 09:00 [entrez] -PHST- 2009/08/22 09:00 [pubmed] -PHST- 2009/09/18 06:00 [medline] -PST - ppublish -SO - Pol Arch Med Wewn. 2009 Jun;119(6):349-53. - -PMID- 22673498 -OWN - NLM -STAT- MEDLINE -DCOM- 20120823 -LR - 20211021 -IS - 1476-5462 (Electronic) -IS - 0969-7128 (Linking) -VI - 19 -IP - 6 -DP - 2012 Jun -TI - Sarcoplasmic reticulum and calcium cycling targeting by gene therapy. -PG - 596-9 -LID - 10.1038/gt.2012.34 [doi] -AB - Although progress in conventional treatments is making steady and incremental - gains to reduce mortality associated with heart failure (HF), there remains a - need to explore potentially new therapeutic approaches. HF induced by different - etiologies such as coronary artery disease, hypertension, diabetes, infection or - inflammation results generally in calcium cycling dysregulation at the myocyte - level. Recent advances in understanding of the molecular basis of these calcium - cycling abnormalities, together with the evolution of increasingly efficient gene - transfer technology, has placed HF within the reach of gene-based therapy. - Furthermore, the recent successful completion of a phase 2 trial targeting the - sarcoplasmic reticulum calcium pump ushers in a new era for gene therapy for the - treatment of HF. -FAU - Hulot, J-S -AU - Hulot JS -AD - Cardiovascular Research Center Mount Sinai School of Medicine, One Gustave L Levy - Place, New York, NY 10029, USA. -FAU - Senyei, G -AU - Senyei G -FAU - Hajjar, R J -AU - Hajjar RJ -LA - eng -GR - HL088434/HL/NHLBI NIH HHS/United States -GR - P50 HL112324/HL/NHLBI NIH HHS/United States -GR - R01 HL119046/HL/NHLBI NIH HHS/United States -GR - HL100396/HL/NHLBI NIH HHS/United States -GR - HL080498/HL/NHLBI NIH HHS/United States -GR - P20 HL100396/HL/NHLBI NIH HHS/United States -GR - HL083156/HL/NHLBI NIH HHS/United States -GR - NIH HL093183/HL/NHLBI NIH HHS/United States -GR - HL071763/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120517 -PL - England -TA - Gene Ther -JT - Gene therapy -JID - 9421525 -RN - EC 3.6.3.8 (Sarcoplasmic Reticulum Calcium-Transporting ATPases) -SB - IM -MH - Animals -MH - Clinical Trials as Topic -MH - Gene Targeting/methods -MH - Gene Transfer Techniques -MH - Genetic Therapy/*methods -MH - Heart Failure/*therapy -MH - Humans -MH - Sarcoplasmic Reticulum Calcium-Transporting ATPases/*genetics -EDAT- 2012/06/08 06:00 -MHDA- 2012/08/24 06:00 -CRDT- 2012/06/08 06:00 -PHST- 2012/06/08 06:00 [entrez] -PHST- 2012/06/08 06:00 [pubmed] -PHST- 2012/08/24 06:00 [medline] -AID - gt201234 [pii] -AID - 10.1038/gt.2012.34 [doi] -PST - ppublish -SO - Gene Ther. 2012 Jun;19(6):596-9. doi: 10.1038/gt.2012.34. Epub 2012 May 17. - -PMID- 21797844 -OWN - NLM -STAT- MEDLINE -DCOM- 20120508 -LR - 20211020 -IS - 1476-5381 (Electronic) -IS - 0007-1188 (Print) -IS - 0007-1188 (Linking) -VI - 165 -IP - 3 -DP - 2012 Feb -TI - Microvascular responsiveness in obesity: implications for therapeutic - intervention. -PG - 544-60 -LID - 10.1111/j.1476-5381.2011.01606.x [doi] -AB - Obesity has detrimental effects on the microcirculation. Functional changes in - microvascular responsiveness may increase the risk of developing cardiovascular - complications in obese patients. Emerging evidence indicates that selective - therapeutic targeting of the microvessels may prevent life-threatening - obesity-related vascular complications, such as ischaemic heart disease, heart - failure and hypertension. It is also plausible that alterations in adipose tissue - microcirculation contribute to the development of obesity. Therefore, targeting - adipose tissue arterioles could represent a novel approach to reducing obesity. - This review aims to examine recent studies that have been focused on vasomotor - dysfunction of resistance arteries in obese humans and animal models of obesity. - Particularly, findings in coronary resistance arteries are contrasted to those - obtained in other vascular beds. We provide examples of therapeutic attempts, - such as use of statins, ACE inhibitors and insulin sensitizers to prevent - obesity-related microvascular complications. We further identify some of the - important challenges and opportunities going forward. LINKED ARTICLES: This - article is part of a themed section on Fat and Vascular Responsiveness. To view - the other articles in this section visit - http://dx.doi.org/10.1111/bph.2012.165.issue-3. -CI - © 2011 The Authors. British Journal of Pharmacology © 2011 The British - Pharmacological Society. -FAU - Bagi, Zsolt -AU - Bagi Z -AD - Department of Pharmacology, University of Oxford, UK Department of Physiology, - New York Medical College, Valhalla, New York, USA. zsolt.bagi@pharm.ox.ac.uk -FAU - Feher, Attila -AU - Feher A -FAU - Cassuto, James -AU - Cassuto J -LA - eng -GR - R01 HL104126/HL/NHLBI NIH HHS/United States -GR - P0HL43023/PHS HHS/United States -GR - BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Br J Pharmacol -JT - British journal of pharmacology -JID - 7502536 -RN - 0 (Adipokines) -RN - 0 (Reactive Oxygen Species) -SB - IM -MH - Adipokines/metabolism -MH - Adipose Tissue/blood supply/metabolism/*physiopathology -MH - Animals -MH - Arteries/*physiopathology -MH - Endothelium, Vascular/physiopathology -MH - Humans -MH - Microcirculation -MH - Obesity/drug therapy/metabolism/*physiopathology -MH - Reactive Oxygen Species/metabolism -MH - Vascular Diseases/drug therapy/metabolism/*physiopathology -PMC - PMC3315030 -EDAT- 2011/07/30 06:00 -MHDA- 2012/05/09 06:00 -PMCR- 2013/02/01 -CRDT- 2011/07/30 06:00 -PHST- 2011/07/30 06:00 [entrez] -PHST- 2011/07/30 06:00 [pubmed] -PHST- 2012/05/09 06:00 [medline] -PHST- 2013/02/01 00:00 [pmc-release] -AID - 10.1111/j.1476-5381.2011.01606.x [doi] -PST - ppublish -SO - Br J Pharmacol. 2012 Feb;165(3):544-60. doi: 10.1111/j.1476-5381.2011.01606.x. - -PMID- 20452547 -OWN - NLM -STAT- MEDLINE -DCOM- 20100923 -LR - 20221207 -IS - 1558-2264 (Electronic) -IS - 0733-8651 (Linking) -VI - 28 -IP - 2 -DP - 2010 May -TI - Acute type A aortic dissection: surgical intervention for all: PRO. -PG - 317-23 -LID - 10.1016/j.ccl.2010.01.012 [doi] -AB - Acute aortic dissection remains the most common of all aortic catastrophes and is - associated with significant morbidity and mortality. Urgent surgical intervention - should be considered in all patients with acute type A aortic dissection. - Immediate repair is performed for those who are hypotensive due to rupture and - tamponade and who exhibit malperfusion of the coronary, cerebrovascular, - visceral, or peripheral arterial systems. Selective delayed management with - eventual repair may be assumed in patients with type A intramural hematoma and in - those with coma (potential neurologic devastation), assuming that neurologic - status improves. Urgent repair should not be precluded in patients presenting - with active stroke, older age, and previous cardiac surgery. Ultimately, each - patient should be individualized and the decision to intervene left to the - surgeon. -CI - Copyright 2010 Elsevier Inc. All rights reserved. -FAU - Estrera, Anthony L -AU - Estrera AL -AD - Department of Cardiothoracic and Vascular Surgery, University of Texas Medical - School, Memorial Hermann Heart and Vascular Institute, 6400 Fannin Street Suite - 2850, Houston, TX 77030, USA. Anthony.l.estrera@uth.tmc.edu -FAU - Safi, Hazim J -AU - Safi HJ -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -SB - IM -CIN - Cardiol Clin. 2010 May;28(2):325-31. doi: 10.1016/j.ccl.2010.02.010. PMID: - 20452548 -CIN - Cardiol Clin. 2010 May;28(2):333-4. doi: 10.1016/j.ccl.2010.02.014. PMID: - 20452549 -MH - Acute Disease -MH - Aortic Dissection/complications/physiopathology/*surgery -MH - Aorta, Thoracic/*surgery -MH - Aortic Aneurysm, Thoracic/complications/physiopathology/*surgery -MH - Blood Pressure -MH - Cerebrovascular Circulation -MH - Disease Progression -MH - Humans -MH - Risk Factors -MH - Stroke/etiology/prevention & control -MH - Vascular Surgical Procedures/*methods -RF - 32 -EDAT- 2010/05/11 06:00 -MHDA- 2010/09/24 06:00 -CRDT- 2010/05/11 06:00 -PHST- 2010/05/11 06:00 [entrez] -PHST- 2010/05/11 06:00 [pubmed] -PHST- 2010/09/24 06:00 [medline] -AID - S0733-8651(10)00013-5 [pii] -AID - 10.1016/j.ccl.2010.01.012 [doi] -PST - ppublish -SO - Cardiol Clin. 2010 May;28(2):317-23. doi: 10.1016/j.ccl.2010.01.012. - -PMID- 22951386 -OWN - NLM -STAT- MEDLINE -DCOM- 20130906 -LR - 20130206 -IS - 1879-1336 (Electronic) -IS - 1054-8807 (Linking) -VI - 22 -IP - 2 -DP - 2013 Mar-Apr -TI - Emerging role of epigenetics and miRNA in diabetic cardiomyopathy. -PG - 117-25 -LID - S1054-8807(12)00094-4 [pii] -LID - 10.1016/j.carpath.2012.07.004 [doi] -AB - The prevalence of heart failure independent of coronary artery disease and - hypertension is increasing rapidly in diabetic patients. Thus, this - pathophysiology has been recognized as a distinct clinical entity termed - "diabetic cardiomyopathy." Several studies support the notion that diabetes is a - threatening insult for the myocardium resulting in functional, cellular, and - structural changes manifesting as a cardiac myopathy. Recent data suggested that - epigenetics including DNA and histone modifications as well as microRNAs play an - important role in the development of cardiac diseases. The role of epigenetics in - diabetes is largely recognized; however, its role in diabetes-associated - cardiomyopathy remains elusive. Thus, molecular, cellular, and functional - modulations in the diabetic cardiomyopathy will be investigated in this review. - Moreover, particular attention will be drawn on the epigenetic mechanisms that - may play an important role in the pathophysiology of diabetic cardiomyopathy. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Asrih, Mohamed -AU - Asrih M -AD - Division of Cardiology, Foundation for Medical Research, University of Geneva - Medical School, 1211 Geneva 4, Switzerland. mohamed.asrih@unige.ch -FAU - Steffens, Sabine -AU - Steffens S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120828 -PL - United States -TA - Cardiovasc Pathol -JT - Cardiovascular pathology : the official journal of the Society for Cardiovascular - Pathology -JID - 9212060 -RN - 0 (Histones) -RN - 0 (MicroRNAs) -RN - EC 2.7.11.13 (Protein Kinase C) -RN - EC 3.6.3.8 (Sarcoplasmic Reticulum Calcium-Transporting ATPases) -SB - IM -MH - DNA Methylation -MH - Diabetic Cardiomyopathies/*genetics/pathology/physiopathology -MH - Dyslipidemias/complications/metabolism -MH - *Epigenesis, Genetic -MH - Histones/metabolism -MH - Humans -MH - Hyperglycemia/complications/metabolism -MH - MicroRNAs/*genetics -MH - Models, Cardiovascular -MH - Oxidative Stress -MH - Protein Kinase C/metabolism -MH - Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism -EDAT- 2012/09/07 06:00 -MHDA- 2013/09/07 06:00 -CRDT- 2012/09/07 06:00 -PHST- 2012/01/27 00:00 [received] -PHST- 2012/07/06 00:00 [revised] -PHST- 2012/07/27 00:00 [accepted] -PHST- 2012/09/07 06:00 [entrez] -PHST- 2012/09/07 06:00 [pubmed] -PHST- 2013/09/07 06:00 [medline] -AID - S1054-8807(12)00094-4 [pii] -AID - 10.1016/j.carpath.2012.07.004 [doi] -PST - ppublish -SO - Cardiovasc Pathol. 2013 Mar-Apr;22(2):117-25. doi: 10.1016/j.carpath.2012.07.004. - Epub 2012 Aug 28. - -PMID- 19734497 -OWN - NLM -STAT- MEDLINE -DCOM- 20091216 -LR - 20090907 -IS - 1473-0480 (Electronic) -IS - 0306-3674 (Linking) -VI - 43 -IP - 9 -DP - 2009 Sep -TI - Incidence and aetiology of sudden cardiac death in young athletes: an - international perspective. -PG - 644-8 -LID - 10.1136/bjsm.2008.054718 [doi] -AB - The incidence of sudden cardiac death (SCD) among young athletes is estimated to - be 1-3 per 100,000 person years, and may be underestimated. The risk of SCD in - athletes is higher than in non-athletes because of several factors associated - with sports activity that increase the risk in people with an underlying - cardiovascular abnormality. A clear gender difference in the incidence of SCD - exists in young athletes, with the risk in male athletes being up to 9 times - higher than in female athletes. The most common causes of SCD in young athletes - is underlying inherited/congenital cardiac disease, such as cardiomyopathies, - congenital coronary anomalies and ion channelopathies. Blunt chest trauma also - may cause ventricular fibrillation in a structurally normal heart, known as - commotio cordis. Although geographical differences in the causes of SCD in young - athletes have been reported, these disparities are more likely to be related to - the type and implementation of pre-participation screening leading to the - identification of athletes at risk, rather than reflecting a truly different - ethiology. More studies are needed to clarify the role of ethnicity in the - prevalence of diseases known to cause SCD in young athletes. -FAU - Borjesson, M -AU - Borjesson M -AD - SU/Ostra, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden. - mats.brjesson@telia.com -FAU - Pelliccia, A -AU - Pelliccia A -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Br J Sports Med -JT - British journal of sports medicine -JID - 0432520 -SB - IM -MH - Death, Sudden, Cardiac/*epidemiology/ethnology/*etiology -MH - Doping in Sports -MH - Female -MH - Humans -MH - Incidence -MH - Male -MH - Risk Factors -MH - Sex Factors -MH - Sports/*physiology -MH - Young Adult -RF - 60 -EDAT- 2009/09/08 06:00 -MHDA- 2009/12/17 06:00 -CRDT- 2009/09/08 06:00 -PHST- 2009/09/08 06:00 [entrez] -PHST- 2009/09/08 06:00 [pubmed] -PHST- 2009/12/17 06:00 [medline] -AID - 43/9/644 [pii] -AID - 10.1136/bjsm.2008.054718 [doi] -PST - ppublish -SO - Br J Sports Med. 2009 Sep;43(9):644-8. doi: 10.1136/bjsm.2008.054718. - -PMID- 21254900 -OWN - NLM -STAT- MEDLINE -DCOM- 20110610 -LR - 20131121 -IS - 1365-2060 (Electronic) -IS - 0785-3890 (Linking) -VI - 43 -IP - 2 -DP - 2011 Mar -TI - Old and new anticoagulant drugs: a minireview. -PG - 116-23 -LID - 10.3109/07853890.2010.539250 [doi] -AB - Abstract The limits of traditional anticoagulants, such as heparin and warfarin, - have prompted the search for new agents for prophylaxis and treatment of arterial - and venous thromboembolism, including factor Xa and thrombin inhibitors. These - agents can be given orally, and their most significant advantage is that no - laboratory monitoring is needed. The anti-Xa inhibitor rivaroxaban and the direct - thrombin inhibitor dabigatran etexilate are licensed for prophylaxis of venous - thromboembolism (VTE) in high-risk orthopedic surgery. They are at least as safe - and effective as heparins but much more expensive. Dabigatran, rivaroxaban, and - other agents currently in the pipeline of clinical development have the potential - to replace warfarin in the two most frequent indications for anticoagulation, - i.e. secondary prophylaxis of VTE and atrial fibrillation. Prevention and - treatment of coronary artery thrombosis in patients with ischemic heart disease - is another area of investigation for the role of new anticoagulants. These drugs - have the potential to meet some currently unmet needs of traditional - anticoagulants, but available clinical data warrant confirmation and expansion. - Lack of specific antidotes for anticoagulation reversal and the high cost are - important limitations of their use. -FAU - Mannucci, Pier Mannuccio -AU - Mannucci PM -AD - Scientific Direction, IRCCS Cà Granda Foundation Maggiore Policlinico Hospital, - Milan, Italy. pmmannucci@libero.it -FAU - Franchini, Massimo -AU - Franchini M -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -DEP - 20110124 -PL - England -TA - Ann Med -JT - Annals of medicine -JID - 8906388 -RN - 0 (Anticoagulants) -RN - 5Q7ZVV76EI (Warfarin) -RN - 9005-49-6 (Heparin) -SB - IM -MH - Animals -MH - Anticoagulants/adverse effects/pharmacology/*therapeutic use -MH - Atrial Fibrillation/drug therapy -MH - *Drug Design -MH - Heparin/adverse effects/therapeutic use -MH - Humans -MH - Thromboembolism/*drug therapy/prevention & control -MH - Warfarin/adverse effects/therapeutic use -EDAT- 2011/01/25 06:00 -MHDA- 2011/06/11 06:00 -CRDT- 2011/01/25 06:00 -PHST- 2011/01/25 06:00 [entrez] -PHST- 2011/01/25 06:00 [pubmed] -PHST- 2011/06/11 06:00 [medline] -AID - 10.3109/07853890.2010.539250 [doi] -PST - ppublish -SO - Ann Med. 2011 Mar;43(2):116-23. doi: 10.3109/07853890.2010.539250. Epub 2011 Jan - 24. - -PMID- 24513079 -OWN - NLM -STAT- MEDLINE -DCOM- 20150212 -LR - 20231017 -IS - 1095-8584 (Electronic) -IS - 0022-2828 (Linking) -VI - 71 -DP - 2014 Jun -TI - The interplay between autophagy and apoptosis in the diabetic heart. -PG - 71-80 -LID - S0022-2828(13)00313-1 [pii] -LID - 10.1016/j.yjmcc.2013.10.014 [doi] -AB - Diabetic cardiomyopathy is characterized by ventricular dysfunction that occurs - in diabetic patients independent of coronary artery disease, hypertension, and - any other cardiovascular diseases. Diabetic cardiomyopathy has become a major - cause of diabetes-related mortality. Thus, an urgent need exists to clarify the - mechanism of pathogenesis. Emerging evidence demonstrates that diabetes induces - cardiomyocyte apoptosis and suppresses cardiac autophagy, indicating that the - interplay between the autophagy and apoptotic cell death pathways is important in - the pathogenesis of diabetic cardiomyopathy. This review highlights recent - advances in the crosstalk between autophagy and apoptosis and its importance in - the development of diabetic cardiomyopathy. This article is part of a Special - Issue entitled "Protein Quality Control, the Ubiquitin Proteasome System, and - Autophagy". -CI - © 2013. -FAU - Ouyang, Changhan -AU - Ouyang C -AD - Section of Molecular Medicine, Department of Medicine, University of Oklahoma - Health Sciences Center, Oklahoma City, OK, USA. -FAU - You, Jieyun -AU - You J -AD - Section of Molecular Medicine, Department of Medicine, University of Oklahoma - Health Sciences Center, Oklahoma City, OK, USA. -FAU - Xie, Zhonglin -AU - Xie Z -AD - Section of Molecular Medicine, Department of Medicine, University of Oklahoma - Health Sciences Center, Oklahoma City, OK, USA. Electronic address: - zxie@ouhsc.edu. -LA - eng -GR - 1P20RR024215-01/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131026 -PL - England -TA - J Mol Cell Cardiol -JT - Journal of molecular and cellular cardiology -JID - 0262322 -SB - IM -MH - Animals -MH - Apoptosis/*physiology -MH - Autophagy/*physiology -MH - Diabetes Mellitus/*pathology -MH - Diabetic Cardiomyopathies/*pathology -MH - Humans -MH - Myocytes, Cardiac/pathology -OTO - NOTNLM -OT - AMPK -OT - Apoptosis -OT - Autophagy -OT - Diabetic cardiomyopathy -EDAT- 2014/02/12 06:00 -MHDA- 2015/02/13 06:00 -CRDT- 2014/02/12 06:00 -PHST- 2013/07/03 00:00 [received] -PHST- 2013/10/07 00:00 [revised] -PHST- 2013/10/21 00:00 [accepted] -PHST- 2014/02/12 06:00 [entrez] -PHST- 2014/02/12 06:00 [pubmed] -PHST- 2015/02/13 06:00 [medline] -AID - S0022-2828(13)00313-1 [pii] -AID - 10.1016/j.yjmcc.2013.10.014 [doi] -PST - ppublish -SO - J Mol Cell Cardiol. 2014 Jun;71:71-80. doi: 10.1016/j.yjmcc.2013.10.014. Epub - 2013 Oct 26. - -PMID- 23148075 -OWN - NLM -STAT- MEDLINE -DCOM- 20130918 -LR - 20121214 -IS - 1873-734X (Electronic) -IS - 1010-7940 (Linking) -VI - 43 -IP - 1 -DP - 2013 Jan -TI - The acquired cardiac disease domain: the next 5 years. -PG - 223-5 -LID - 10.1093/ejcts/ezs440 [doi] -AB - At a recent in-house meeting at the European Association for Cardiothoracic - Surgery (EACTS) headquarters in Windsor, the Chairs of the four domains were - asked by the President to present their perception of the next 5 years in their - respective domains. This review represents a distillation of our discussions on - adult cardiac surgery. Advances in technology and imaging are having a radical - effect on the working lives of surgeons. In clinical practice, the growth of - heart teams and the breaking down of artificial barriers between specialities are - altering the way we practice for the better. We see the development of hybrid - approaches to many areas such as coronary artery surgery and operations on the - thoracic aorta. These changes require careful analysis to ensure that they - produce better outcomes that are also cost-effective. All health-care systems are - at breaking point, and it is our responsibility to harness new technology to - benefit our patients. This is all part of placing the patient at the centre of - our activities. Hence, we see the involvement of patients in the design and - analysis of clinical trials, which also require great mutual trust and - cooperation between surgeons in different countries. Because of the dramatic - changes in the pattern of working, we have had to alter our patterns of training - and education, and we will continue to make significant innovations in the - future. These are exciting challenges that will keep us all busy for the next 5 - years at least. -FAU - Pepper, John R -AU - Pepper JR -AD - Department of Cardiothoracic Surgery, Royal Brompton Hospital, London, UK. - j.pepper@rbht.nhs.uk -LA - eng -PT - Journal Article -PT - Review -DEP - 20121112 -PL - Germany -TA - Eur J Cardiothorac Surg -JT - European journal of cardio-thoracic surgery : official journal of the European - Association for Cardio-thoracic Surgery -JID - 8804069 -SB - IM -MH - Adult -MH - Biomedical Research -MH - Clinical Trials as Topic -MH - Delivery of Health Care -MH - Europe -MH - Humans -MH - Societies, Medical -MH - Thoracic Surgery/education/*organization & administration -MH - Thoracic Surgical Procedures/methods -EDAT- 2012/11/14 06:00 -MHDA- 2013/09/21 06:00 -CRDT- 2012/11/14 06:00 -PHST- 2012/11/14 06:00 [entrez] -PHST- 2012/11/14 06:00 [pubmed] -PHST- 2013/09/21 06:00 [medline] -AID - ezs440 [pii] -AID - 10.1093/ejcts/ezs440 [doi] -PST - ppublish -SO - Eur J Cardiothorac Surg. 2013 Jan;43(1):223-5. doi: 10.1093/ejcts/ezs440. Epub - 2012 Nov 12. - -PMID- 22964653 -OWN - NLM -STAT- MEDLINE -DCOM- 20130613 -LR - 20220321 -IS - 1558-2035 (Electronic) -IS - 1558-2027 (Linking) -VI - 14 -IP - 1 -DP - 2013 Jan -TI - Copeptin: a new marker in cardiology. -PG - 19-25 -LID - 10.2459/JCM.0b013e3283590d59 [doi] -AB - Copeptin, the C-terminal part of the prohormone of vasopressin (AVP), is released - together with AVP in stoichiometric concentrations reflecting an individual's - stress level. Copeptin has come to be regarded as an important marker for - identifying high-risk patients and predicting outcomes in a variety of diseases. - It improves the clinical value of commonly used biomarkers and the tools of risk - stratification. Elevated AVP activation and higher copeptin concentrations have - been previously described in acute systemic disorders. However, the field that - could benefit the most from the introduction of copeptin measurements into - practice is that of cardiovascular disease. Determination of copeptin level - emerges as a fast and reliable method for differential diagnosis, especially in - acute coronary syndromes. A particular role in the diagnosis of acute myocardial - infarction (AMI) is attributed to the combination of copeptin and troponin. - According to available sources, such a combination allows AMI to be ruled out - with very high sensitivity and negative predictive value. Moreover, elevated - copeptin levels correlate with a worse prognosis and a higher risk of adverse - events after AMI, especially in patients who develop heart failure. Some authors - suggest that copeptin might be valuable in defining the moment of the - introduction of treatment and its monitoring in high-risk patients. The - introduction of copeptin into clinical practice might also provide a benefit on a - larger scale by suggesting changes in the allocation of financial resources - within the health system. Although very promising, further larger trials are - required in order to assess the clinical benefits of copeptin in everyday - practice and patient care. -FAU - Morawiec, Beata -AU - Morawiec B -AD - Second Department of Cardiology, Silesian Medical University of Katowice, - Katowice, Poland. beamorawiec@wp.pl -FAU - Kawecki, Damian -AU - Kawecki D -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Cardiovasc Med (Hagerstown) -JT - Journal of cardiovascular medicine (Hagerstown, Md.) -JID - 101259752 -RN - 0 (Biomarkers) -RN - 0 (Glycopeptides) -RN - 0 (copeptins) -SB - IM -MH - Biomarkers/*blood -MH - Cardiology -MH - Cardiovascular Diseases/*blood -MH - Glycopeptides/*blood -MH - Humans -MH - Prognosis -EDAT- 2012/09/12 06:00 -MHDA- 2013/06/14 06:00 -CRDT- 2012/09/12 06:00 -PHST- 2012/09/12 06:00 [entrez] -PHST- 2012/09/12 06:00 [pubmed] -PHST- 2013/06/14 06:00 [medline] -AID - 10.2459/JCM.0b013e3283590d59 [doi] -PST - ppublish -SO - J Cardiovasc Med (Hagerstown). 2013 Jan;14(1):19-25. doi: - 10.2459/JCM.0b013e3283590d59. - -PMID- 23331845 -OWN - NLM -STAT- MEDLINE -DCOM- 20130701 -LR - 20250529 -IS - 2046-4924 (Electronic) -IS - 1366-5278 (Print) -IS - 1366-5278 (Linking) -VI - 17 -IP - 1 -DP - 2013 -TI - Systematic review, meta-analysis and economic modelling of diagnostic strategies - for suspected acute coronary syndrome. -PG - v-vi, 1-188 -LID - 10.3310/hta17010 [doi] -AB - BACKGROUND: Current practice for suspected acute coronary syndrome (ACS) involves - troponin testing 10-12 hours after symptom onset to diagnose myocardial - infarction (MI). Patients with a negative troponin can be investigated further - with computed tomographic coronary angiography (CTCA) or exercise - electrocardiography (ECG). OBJECTIVES: We aimed to estimate the diagnostic - accuracy of early biomarkers for MI, the prognostic accuracy of biomarkers for - major adverse cardiac adverse events (MACEs) in troponin-negative patients, the - diagnostic accuracy of CTCA and exercise ECG for coronary artery disease (CAD) - and the prognostic accuracy of CTCA and exercise ECG for MACEs in patients with - suspected ACS. We then aimed to estimate the cost-effectiveness of using - alternative biomarker strategies to diagnose MI, and using biomarkers, CTCA and - exercise ECG to risk-stratify troponin-negative patients. DATA SOURCES: We - searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations; Cumulative - Index of Nursing and Allied Health Literature (CINAHL), EMBASE, Web of Science, - Cochrane Central Database of Controlled Trials (CENTRAL), Cochrane Database of - Systematic Reviews (CDSR), NHS Database of Abstracts of Reviews of Effects (DARE) - and the Health Technology Assessment database from 1985 (CTCA review) or 1995 - (biomarkers review) to November 2010, reviewed citation lists and contacted - experts to identify relevant studies. REVIEW METHODS: Diagnostic studies were - assessed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) - tool and prognostic studies using a framework adapted for the project. - Meta-analysis was conducted using bayesian Markov chain Monte Carlo simulation. - We developed a decision-analysis model to evaluate the cost-effectiveness of - alternative biomarker strategies to diagnose MI, and the cost-effectiveness of - biomarkers, CTCA or exercise ECG to risk-stratify patients with a negative - troponin. Strategies were applied to a theoretical cohort of patients with - suspected ACS. Cost-effectiveness was estimated as the incremental cost per - quality-adjusted life-year (QALY) of each strategy compared with the next most - effective, taking a health-service perspective and a lifetime horizon. RESULTS: - Sensitivity and specificity (95% predictive interval) were 77% (29-96%) and 93% - (46-100%) for troponin I, 80% (33-97%) and 91% (53-99%) for troponin T (99th - percentile threshold), 81% (50-95%) and 80% (26-98%) for quantitative heart-type - fatty acid-binding protein (H-FABP), 68% (11-97%) and 92% (20-100%) for - qualitative H-FABP, 77% (19-98%) and 39% (2-95%) for ischaemia-modified albumin - and 62% (35-83%) and 83% (35-98%) for myoglobin. CTCA had 94% (61-99%) - sensitivity and 87% (16-100%) specificity for CAD. Positive CTCA and - positive-exercise ECG had relative risks of 5.8 (0.6-24.5) and 8.0 (2.3-22.7) for - MACEs. In most scenarios in the economic analysis presentation, high-sensitivity - troponin measurement was the most effective strategy with an incremental - cost-effectiveness ratio (ICER) of less than the £20,000-30,000/QALY threshold - (ICER £7487-17,191/QALY). CTCA appeared to be the most cost-effective strategy - for patients with a negative troponin, with an ICER of £11,041/QALY. However, - when a lower MACE rate was assumed, CTCA had a high ICER (£262,061/QALY) and the - no-testing strategy was optimal. LIMITATIONS: There was substantial variation - between the primary studies and heterogeneity in their results. Findings of the - economic model were dependent on assumptions regarding the value of detecting and - treating positive cases. CONCLUSIONS: Although presentation troponin has - suboptimal sensitivity, measurement of a 10-hour troponin level is unlikely to be - cost-effective in most scenarios compared with a high-sensitivity presentation - troponin. CTCA may be a cost-effective strategy for troponin-negative patients, - but further research is required to estimate the effect of CTCA on event rates - and health-care costs. FUNDING: The National Institute for Health Research Health - Technology Assessment programme. -FAU - Goodacre, S -AU - Goodacre S -AD - School of Health and Related Research (ScHARR), University of Sheffield, - Sheffield, UK. -FAU - Thokala, P -AU - Thokala P -FAU - Carroll, C -AU - Carroll C -FAU - Stevens, J W -AU - Stevens JW -FAU - Leaviss, J -AU - Leaviss J -FAU - Al Khalaf, M -AU - Al Khalaf M -FAU - Collinson, P -AU - Collinson P -FAU - Morris, F -AU - Morris F -FAU - Evans, P -AU - Evans P -FAU - Wang, J -AU - Wang J -LA - eng -GR - 09/22/21/DH_/Department of Health/United Kingdom -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -PT - Systematic Review -PL - England -TA - Health Technol Assess -JT - Health technology assessment (Winchester, England) -JID - 9706284 -RN - 0 (Biomarkers) -RN - 0 (FABP3 protein, human) -RN - 0 (Fatty Acid Binding Protein 3) -RN - 0 (Fatty Acid-Binding Proteins) -RN - 0 (Myoglobin) -RN - 0 (Serum Albumin) -RN - 0 (Troponin T) -RN - 0 (ischemia-modified albumin) -RN - ZIF514RVZR (Serum Albumin, Human) -SB - IM -MH - Acute Coronary Syndrome/*blood/*diagnosis -MH - Bayes Theorem -MH - Biomarkers/blood -MH - Cost-Benefit Analysis -MH - Decision Support Techniques -MH - Electrocardiography -MH - Exercise Test -MH - Fatty Acid Binding Protein 3 -MH - Fatty Acid-Binding Proteins/blood -MH - Humans -MH - *Models, Econometric -MH - Myocardial Infarction/*blood/*diagnosis -MH - Myoglobin/blood -MH - Prognosis -MH - Quality-Adjusted Life Years -MH - Sensitivity and Specificity -MH - Serum Albumin -MH - Serum Albumin, Human -MH - Troponin T/blood -PMC - PMC4780933 -EDAT- 2013/01/22 06:00 -MHDA- 2013/07/03 06:00 -PMCR- 2016/03/07 -CRDT- 2013/01/22 06:00 -PHST- 2013/01/22 06:00 [entrez] -PHST- 2013/01/22 06:00 [pubmed] -PHST- 2013/07/03 06:00 [medline] -PHST- 2016/03/07 00:00 [pmc-release] -AID - 10.3310/hta17010 [doi] -PST - ppublish -SO - Health Technol Assess. 2013;17(1):v-vi, 1-188. doi: 10.3310/hta17010. - -PMID- 20465095 -OWN - NLM -STAT- MEDLINE -DCOM- 20100601 -LR - 20131121 -IS - 0042-773X (Print) -IS - 0042-773X (Linking) -VI - 56 -IP - 4 -DP - 2010 Apr -TI - [Endocrine abnormalities and vessels in patients with diabetes]. -PG - 280-3 -AB - Endocrine impairment is more common in patients with diabetes than in general - population. Both hyper- and hypothyroidism increases cardiovascular morbidity and - mortality. Subclinical hypothyroidism is a risk factor for coronary hearth - disease in patients younger than 65 years. In elderly is its influence - questionable or even preventive and the benefit of substitution should be - weighted against the risks. Treatment with glucocorticoids in a dose of 7.5 mg - methylprednisolone and higher considerably increases risk of vascular impairment. - Patients cured from endogenous Cushing's syndrome maintain increased - cardiovascular risk factors and structural changes of vessels. Subclinical - hypercortisolism seems to have little effect. Growth hormone (GH) insufficiency - increases cardiovascular risks and contributes to increased mortality of these - patients. To the contrary increased GH production in acromegaly effect more heart - than vessels. Hypogonadism is established risk factor for ischemic accidents in - men. The relationship between hypogonadism and diabetes is bidirectional. Low - testosterone level increases the risk of type-2 diabetes and in diabetics is the - testosterone level often low. Substitution with testosterone can not only - ameliorate hypogonadal symptoms but also decrease cardiovascular risk and even - improve control of diabetes. -FAU - Cáp, J -AU - Cáp J -AD - II. interní klinika Lékarské fakulty UK a FN Hradec Králové. capj@lfhk.cuni.cz -LA - cze -PT - English Abstract -PT - Journal Article -PT - Review -TT - Endokrinní odchylky a cévy u diabetiků. -PL - Czech Republic -TA - Vnitr Lek -JT - Vnitrni lekarstvi -JID - 0413602 -RN - 0 (Glucocorticoids) -RN - 0 (Thyroid Hormones) -RN - 3XMK78S47O (Testosterone) -RN - 9002-72-6 (Growth Hormone) -SB - IM -MH - Blood Vessels/*pathology -MH - Cardiovascular Diseases/*complications -MH - Diabetic Angiopathies/*complications/pathology -MH - Endocrine System Diseases/*complications -MH - Glucocorticoids/pharmacology -MH - Growth Hormone/pharmacology -MH - Humans -MH - Testosterone/pharmacology -MH - Thyroid Hormones/pharmacology -RF - 31 -EDAT- 2010/05/15 06:00 -MHDA- 2010/06/02 06:00 -CRDT- 2010/05/15 06:00 -PHST- 2010/05/15 06:00 [entrez] -PHST- 2010/05/15 06:00 [pubmed] -PHST- 2010/06/02 06:00 [medline] -PST - ppublish -SO - Vnitr Lek. 2010 Apr;56(4):280-3. - -PMID- 24188217 -OWN - NLM -STAT- MEDLINE -DCOM- 20140527 -LR - 20220331 -IS - 1558-2264 (Electronic) -IS - 0733-8651 (Linking) -VI - 31 -IP - 4 -DP - 2013 Nov -TI - Massive pulmonary embolism. -PG - 503-18, vii -LID - S0733-8651(13)00068-4 [pii] -LID - 10.1016/j.ccl.2013.07.005 [doi] -AB - Massive pulmonary embolism (PE) is a potentially lethal condition, with death - usually caused by right ventricular (RV) failure and cardiogenic shock. Systemic - thrombolysis (unless contraindicated) is recommended as the first-line treatment - of massive PE to decrease the thromboembolic burden on the RV and increase - pulmonary perfusion. Surgical pulmonary embolectomy or catheter-directed - thrombectomy should be considered in patients with contraindications to - fibrinolysis, or those with persistent hemodynamic compromise or RV dysfunction - despite fibrinolytic therapy. Critical care management predominantly involves - supporting the RV, by optimizing preload, RV contractility, and coronary - perfusion pressure and minimizing afterload. Despite these interventions, - mortality remains high. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Moorjani, Narain -AU - Moorjani N -AD - Department of Cardiothoracic Surgery, Papworth Hospital, University of Cambridge, - Cambridge CB23 3RE, UK. Electronic address: narain.moorjani@papworth.nhs.uk. -FAU - Price, Susanna -AU - Price S -LA - eng -PT - Journal Article -PT - Review -DEP - 20130827 -PL - Netherlands -TA - Cardiol Clin -JT - Cardiology clinics -JID - 8300331 -RN - 0 (Anticoagulants) -RN - 0 (Fibrin Fibrinogen Degradation Products) -RN - 0 (Fibrinolytic Agents) -RN - 0 (fibrin fragment D) -SB - IM -MH - Acute Disease -MH - Anticoagulants/therapeutic use -MH - Catheterization/methods -MH - Critical Care/methods -MH - Echocardiography/methods -MH - Embolectomy/methods -MH - Fibrin Fibrinogen Degradation Products/metabolism -MH - Fibrinolytic Agents/therapeutic use -MH - Heart-Assist Devices -MH - Humans -MH - Long-Term Care/methods -MH - Prognosis -MH - Pulmonary Embolism/diagnosis/etiology/*therapy -MH - Risk Assessment/methods -MH - Risk Factors -MH - Thrombectomy/methods -MH - Thrombolytic Therapy/methods -MH - Treatment Outcome -MH - Vena Cava Filters -MH - Ventricular Dysfunction, Right/drug therapy -OTO - NOTNLM -OT - Anticoagulation -OT - Pulmonary embolectomy -OT - Pulmonary embolism -OT - Right ventricular dysfunction -OT - Thrombolysis -EDAT- 2013/11/06 06:00 -MHDA- 2014/05/28 06:00 -CRDT- 2013/11/06 06:00 -PHST- 2013/11/06 06:00 [entrez] -PHST- 2013/11/06 06:00 [pubmed] -PHST- 2014/05/28 06:00 [medline] -AID - S0733-8651(13)00068-4 [pii] -AID - 10.1016/j.ccl.2013.07.005 [doi] -PST - ppublish -SO - Cardiol Clin. 2013 Nov;31(4):503-18, vii. doi: 10.1016/j.ccl.2013.07.005. Epub - 2013 Aug 27. - -PMID- 19942842 -OWN - NLM -STAT- MEDLINE -DCOM- 20100423 -LR - 20091127 -IS - 0026-4725 (Print) -IS - 0026-4725 (Linking) -VI - 57 -IP - 6 -DP - 2009 Dec -TI - Mediators of target organ damage in hypertension: focus on obesity associated - factors and inflammation. -PG - 687-704 -AB - Arterial hypertension represents a major cardiovascular epidemic in the developed - and developing world. Projections out to 2025 suggest that up to 50% of the adult - populations of Western countries will meet standard guideline definitions of - hypertension and thus require therapeutic intervention both non-pharmacological - or pharmacological. Hyper-tension is also a component of many other major - comorbidities contributing to cardiovascular disease burden. These include - obesity, the metabolic syndrome, hyperlipidaemia, diabetes, and chronic kidney - disease (CKD). Downstream consequences initially presenting as target organ - damage of various degrees include coronary artery disease, cerebrovascular - disease, nephropathy and chronic heart failure. Although elevated blood pressure - per se is undoubtedly the major factor contributing to hypertensive target organ - damage there is clear evidence that other mediators are also crucially involved - in the transition from a healthy to a diseased state of target organs in the - clinical setting of elevated blood pressure. This has obvious consequences for a - multifactorial approach aimed not only at achieving target blood pressure levels - but also at preventing the development or the progression of target organ damage - in order to optimally reduce the overall cardiovascular risk for patients. The - epidemic we are currently facing in regards to obesity is closely associated with - the expected increase in the prevalence of hypertension. A closer look into the - role of obesity and associated factors for the rise in blood pressure and their - role in target organ damage is therefore inevitable. This review will thus focus - on the clinically important aspects of target organ damage associated with - hypertension, particularly obesity related hypertension, and the evidence for the - involvement of neurohormonal activation and inflammatory pathways. -FAU - Dawood, T -AU - Dawood T -AD - Neurovascular Hypertension and Kidney Disease Laboratory, Baker IDI Heart and - Diabetes Institute and Alfred Hospital, Melbourne, Australia. -FAU - Schlaich, M P -AU - Schlaich MP -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Cardioangiol -JT - Minerva cardioangiologica -JID - 0400725 -RN - 0 (Neurotransmitter Agents) -SB - IM -MH - Adult -MH - Albuminuria/diagnosis -MH - Cardiovascular Diseases/*epidemiology/prevention & control -MH - Comorbidity -MH - Developed Countries -MH - Developing Countries -MH - Disease Progression -MH - Endothelium, Vascular/physiopathology -MH - Forecasting -MH - Humans -MH - Hypertension/epidemiology/genetics/pathology/*physiopathology/therapy -MH - Hypertrophy, Left Ventricular/diagnosis/epidemiology/physiopathology -MH - Inflammation -MH - Kidney Diseases/epidemiology/pathology/physiopathology -MH - Neurotransmitter Agents/therapeutic use -MH - Obesity/*complications/epidemiology/pathology -MH - Prevalence -MH - Renin-Angiotensin System/drug effects/physiology -RF - 184 -EDAT- 2009/11/28 06:00 -MHDA- 2010/04/24 06:00 -CRDT- 2009/11/28 06:00 -PHST- 2009/11/28 06:00 [entrez] -PHST- 2009/11/28 06:00 [pubmed] -PHST- 2010/04/24 06:00 [medline] -AID - R05092966 [pii] -PST - ppublish -SO - Minerva Cardioangiol. 2009 Dec;57(6):687-704. - -PMID- 23110790 -OWN - NLM -STAT- MEDLINE -DCOM- 20130312 -LR - 20250626 -IS - 1941-7705 (Electronic) -IS - 1941-7713 (Linking) -VI - 5 -IP - 6 -DP - 2012 Nov -TI - Omega 3 Fatty acids and cardiovascular outcomes: systematic review and - meta-analysis. -PG - 808-18 -LID - 10.1161/CIRCOUTCOMES.112.966168 [doi] -AB - BACKGROUND: Early trials evaluating the effect of omega 3 fatty acids (ω-3 FA) - reported benefits for mortality and cardiovascular events but recent larger - studies trials have variable findings. We assessed the effects of ω-3 FA on - cardiovascular and other important clinical outcomes. METHODS AND RESULTS: We - searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials - for all randomized studies using dietary supplements, dietary interventions, or - both. The primary outcome was a composite of cardiovascular events (mostly - myocardial infarction, stroke, and cardiovascular death). Secondary outcomes were - arrhythmia, cerebrovascular events, hemorrhagic stroke, ischemic stroke, coronary - revascularization, heart failure, total mortality, nonvascular mortality, and - end-stage kidney disease. Twenty studies including 63030 participants were - included. There was no overall effect of ω-3 FA on composite cardiovascular - events (relative risk [RR]=0.96; 95% confidence interval [CI], 0.90-1.03; P=0.24) - or on total mortality (RR=0.95; 95% CI, 0.86-1.04; P=0.28). ω-3 FA did protect - against vascular death (RR=0.86; 95% CI, 0.75-0.99; P=0.03) but not coronary - events (RR=0.86; 95% CI, 0.67-1.11; P=0.24). There was no effect on arrhythmia - (RR=0.99; 95% CI, 0.85-1.16; P=0.92) or cerebrovascular events (RR=1.03; 95% CI, - 0.92-1.16; P=0.59). Adverse events were more common in the treatment group than - the placebo group (RR=1.18, 95% CI, 1.02-1.37; P=0.03), predominantly because of - an excess of gastrointestinal side effects. CONCLUSIONS: ω-3 FA may protect - against vascular disease, but the evidence is not clear-cut, and any benefits are - almost certainly not as great as previously believed. -FAU - Kotwal, Sradha -AU - Kotwal S -AD - George Institute for Global Health, University of Sydney, Sydney, Australia. - skotwal@georgeinstitute.org.au -FAU - Jun, Min -AU - Jun M -FAU - Sullivan, David -AU - Sullivan D -FAU - Perkovic, Vlado -AU - Perkovic V -FAU - Neal, Bruce -AU - Neal B -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -DEP - 20121030 -PL - United States -TA - Circ Cardiovasc Qual Outcomes -JT - Circulation. Cardiovascular quality and outcomes -JID - 101489148 -RN - 0 (Cardiovascular Agents) -RN - 0 (Fatty Acids, Omega-3) -SB - IM -MH - Aged -MH - Cardiovascular Agents/*therapeutic use -MH - Cardiovascular Diseases/mortality/*prevention & control -MH - *Dietary Supplements -MH - Evidence-Based Medicine -MH - Fatty Acids, Omega-3/*therapeutic use -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Odds Ratio -MH - Treatment Outcome -EDAT- 2012/11/01 06:00 -MHDA- 2013/03/13 06:00 -CRDT- 2012/11/01 06:00 -PHST- 2012/11/01 06:00 [entrez] -PHST- 2012/11/01 06:00 [pubmed] -PHST- 2013/03/13 06:00 [medline] -AID - CIRCOUTCOMES.112.966168 [pii] -AID - 10.1161/CIRCOUTCOMES.112.966168 [doi] -PST - ppublish -SO - Circ Cardiovasc Qual Outcomes. 2012 Nov;5(6):808-18. doi: - 10.1161/CIRCOUTCOMES.112.966168. Epub 2012 Oct 30. - -PMID- 17511585 -OWN - NLM -STAT- MEDLINE -DCOM- 20070618 -LR - 20070521 -IS - 1523-0864 (Print) -IS - 1523-0864 (Linking) -VI - 9 -IP - 6 -DP - 2007 Jun -TI - Clinical perspective of obstructive sleep apnea-induced cardiovascular - complications. -PG - 701-10 -AB - Obstructive sleep apnea (OSA) syndrome is a highly prevalent disorder - characterized by recurrent upper airway collapse during sleep, and associated - with repetitive episodes of transient oxygen desaturation during sleep. It - disrupts normal ventilation and sleep architecture, and is typically associated - with excessive daytime sleepiness, snoring, and witnessed apneas. Besides being - associated with neurocognitive impairment, mood and behavioral effects, and - increased risk for work-related and traffic accidents, OSA has also been - implicated in the pathogenesis of various cardiovascular diseases, including - systemic hypertension, coronary artery disease, congestive heart failure, - pulmonary hypertension, stroke, and cardiac arrhythmias. The mechanisms by which - OSA affects the cardiovascular system may involve mechanical effects on - intrathoracic pressure, increased sympathetic activation, intermittent hypoxia, - and endothelial dysfunction. Therapy with continuous positive airway pressure - (CPAP) has been demonstrated to improve cardiopulmonary hemodynamics in patients - with OSA and may reverse the endothelial cell dysfunction. -FAU - Jain, Vivek -AU - Jain V -AD - Division of Pulmonary and Critical Care Medicine, GW Medical Faculty Associates, - The George Washington University, Washington, District of Columbia 20037, USA. - vjain@mfa.gwu.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Antioxid Redox Signal -JT - Antioxidants & redox signaling -JID - 100888899 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*etiology/*pathology -MH - Death, Sudden/pathology -MH - Humans -MH - Hypertension/pathology -MH - Metabolic Diseases/metabolism/pathology -MH - Sleep Apnea, Obstructive/*complications/metabolism/*pathology -MH - Smoking/adverse effects -RF - 121 -EDAT- 2007/05/22 09:00 -MHDA- 2007/06/19 09:00 -CRDT- 2007/05/22 09:00 -PHST- 2007/05/22 09:00 [pubmed] -PHST- 2007/06/19 09:00 [medline] -PHST- 2007/05/22 09:00 [entrez] -AID - 10.1089/ars.2007.1558 [doi] -PST - ppublish -SO - Antioxid Redox Signal. 2007 Jun;9(6):701-10. doi: 10.1089/ars.2007.1558. - -PMID- 23800947 -OWN - NLM -STAT- MEDLINE -DCOM- 20131212 -LR - 20211021 -IS - 1435-1544 (Electronic) -IS - 0938-7412 (Linking) -VI - 24 -IP - 2 -DP - 2013 Jun -TI - [Early repolarisation. A dilemma of risk stratification]. -PG - 115-22 -LID - 10.1007/s00399-013-0270-x [doi] -AB - Early repolarization, involving infero-lateral ST segment elevation and prominent - J waves at the QRS-ST junction has been considered a normal ECG variant for more - than 80 years. More recent studies suggest that this phenomenon is not as benign - as earlier believed and may represent a risk for subsequent ventricular - fibrillation in patients with and without structural heart disease. However, - based on current data it seems unjustified to consider these often accidental ECG - findings a marker for high risk of sudden cardiac death. The concept of a reduced - repolarization reserve developed for the Long QT syndrome can be transformed to - early repolarization syndrome. In general a "fibrillation reserve" is relatively - high but if triggers such as a genetic background, age, gender, influences of the - autonomous nervous system, changes in body temperature, or an acute coronary - syndrome act together ventricular fibrillation may occur. A combination of an - "early repolarization ECG" with syncope and/or a positive family history of - sudden cardiac death may justify defibrillator therapy just on an individual - basis. This review intends to summarize actual aspects of early repolarizations - syndrome and focuses on the dilemma of risk stratification. -FAU - Eckardt, Lars -AU - Eckardt L -AD - Abteilung für Rhythmologie, Department für Kardiologie und Angiologie, - Universitätsklinikum Münster, Albert-Schweitzer Campus 1, D-48149, Münster, - Deutschland. lars.eckardt@ukmuenster.de -FAU - Wasmer, Kristina -AU - Wasmer K -FAU - Köbe, Julia -AU - Köbe J -FAU - Milberg, Peter -AU - Milberg P -FAU - Mönnig, Gerold -AU - Mönnig G -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Frühe Repolarisation. Ein Dilemma der Risikostratifikation. -PL - Germany -TA - Herzschrittmacherther Elektrophysiol -JT - Herzschrittmachertherapie & Elektrophysiologie -JID - 9425873 -SB - IM -MH - *Cardiac Pacing, Artificial -MH - Death, Sudden, Cardiac/*prevention & control -MH - Diagnosis, Differential -MH - Electrocardiography/*methods -MH - Humans -MH - Risk Assessment -MH - Ventricular Fibrillation/*diagnosis/*prevention & control -EDAT- 2013/06/27 06:00 -MHDA- 2013/12/18 06:00 -CRDT- 2013/06/27 06:00 -PHST- 2013/06/27 06:00 [entrez] -PHST- 2013/06/27 06:00 [pubmed] -PHST- 2013/12/18 06:00 [medline] -AID - 10.1007/s00399-013-0270-x [doi] -PST - ppublish -SO - Herzschrittmacherther Elektrophysiol. 2013 Jun;24(2):115-22. doi: - 10.1007/s00399-013-0270-x. - -PMID- 23016712 -OWN - NLM -STAT- MEDLINE -DCOM- 20130816 -LR - 20180605 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 19 -IP - 9 -DP - 2013 -TI - Novel anti-platelet agents for the treatment of stable angina pectoris. -PG - 1581-6 -AB - Antiplatelet treatment is an important element in the medical treatment of - patients with stable angina. Single antiplatelet therapy with low-dose aspirin is - recommended in the absence of contraindications in all patients with diagnosed - chronic stable angina and ischemic heart disease. Dual antiplatelet therapy is - recommended initially for all patients with stable angina undergoing elective - angioplasty with the duration of P2Y12 antagonist administration depending on the - type of coronary stent. Despite the demonstrated clinical benefit in a wide range - of patients, residual risk of ischemic events with aspirin and a P2Y12 inhibitor - has also been attributed to the fact that these agents do not inhibit all - pathways involved in platelet activation and aggregation. Other platelet - activation pathways, including the PAR-1 pathway activated by thrombin (the most - potent platelet activator), remain active in the presence of current antiplatelet - agents. A combination of current therapies with novel agents could provide more - comprehensive platelet inhibition leading to incremental decrease of - cardiovascular events at the expense of increased bleeding risk. The current - review presents traditional and novel antiplatelet treatment options and - discusses the indications for aggressive antiplatelet management in patients with - stable angina pectoris. -FAU - Briasoulis, Alexandros -AU - Briasoulis A -AD - 1st Cardiology Unit, Athens University Medical School, Greece. - alexbriasoulis@gmail.com -FAU - Tousoulis, Dimitris -AU - Tousoulis D -FAU - Bakogiannis, Constantinos -AU - Bakogiannis C -FAU - Papageorgiou, Nikolaos -AU - Papageorgiou N -FAU - Androulakis, Emmanuel -AU - Androulakis E -FAU - Latsios, George -AU - Latsios G -FAU - Chatzis, George -AU - Chatzis G -FAU - Chrysohoou, Christina -AU - Chrysohoou C -FAU - Vogiatzi, Georgia -AU - Vogiatzi G -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Angina Pectoris/*drug therapy -MH - Humans -MH - Platelet Activation -MH - Platelet Aggregation Inhibitors/*therapeutic use -EDAT- 2012/09/29 06:00 -MHDA- 2013/08/21 06:00 -CRDT- 2012/09/29 06:00 -PHST- 2012/08/31 00:00 [received] -PHST- 2012/09/17 00:00 [accepted] -PHST- 2012/09/29 06:00 [entrez] -PHST- 2012/09/29 06:00 [pubmed] -PHST- 2013/08/21 06:00 [medline] -AID - CPD-EPUB-20120918-1 [pii] -PST - ppublish -SO - Curr Pharm Des. 2013;19(9):1581-6. - -PMID- 20550505 -OWN - NLM -STAT- MEDLINE -DCOM- 20110816 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 16 -IP - 23 -DP - 2010 -TI - Adverse effects of cigarette smoke and induction of oxidative stress in - cardiomyocytes and vascular endothelium. -PG - 2551-8 -AB - Active and passive exposure to cigarette smoke (CS) increases the risk of, and - has deleterious effects in, ischaemic heart disease. Exposure to CS increases - infarct size in experimental models of coronary occlusion and reperfusion. Among - many possible mechanisms for these deleterious effects in intact animals and - humans three have more substantial evidence: 1) functional alterations of - endothelial cells, neutrophils and platelets; 2) impaired mitochondrial function - and energy metabolism caused by toxins in CS, including oxidative free radicals; - 3) increased arterial stiffness and vulnerability of the atherosclerotic plaque. - In addition to the various pro-mitogenic, carcinogenic and apoptotic pathways - thought to be affected and upregulated by CS, a direct necrotic action on - cardiomyocytes is also believed to exist. Many, if not all, of these alterations - are caused by oxidative stress, either as a direct consequence of inhalation of - free radicals, or by induction from the vast range of chemicals present in both - the gas and solid phase of tobacco smoke. Here, some of the proposed mechanisms - will be reviewed and their impact on the cardiomyocytes and peripheral - vasculature discussed. -FAU - Varela-Carver, Anabel -AU - Varela-Carver A -AD - Medical Research Council, Clinical Sciences Centre, Hammersmith Hospital, London, - UK. -FAU - Parker, Howard -AU - Parker H -FAU - Kleinert, Christina -AU - Kleinert C -FAU - Rimoldi, Ornella -AU - Rimoldi O -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (DNA, Mitochondrial) -RN - 0 (Tobacco Smoke Pollution) -SB - IM -MH - Animals -MH - DNA, Mitochondrial/metabolism -MH - Endothelium, Vascular/*metabolism/pathology -MH - Humans -MH - Myocytes, Cardiac/*metabolism/pathology -MH - Oxidative Stress/genetics/*physiology -MH - Smoking/adverse effects/genetics/*metabolism -MH - *Tobacco Smoke Pollution/adverse effects -EDAT- 2010/06/17 06:00 -MHDA- 2011/08/17 06:00 -CRDT- 2010/06/17 06:00 -PHST- 2010/05/11 00:00 [received] -PHST- 2010/06/02 00:00 [accepted] -PHST- 2010/06/17 06:00 [entrez] -PHST- 2010/06/17 06:00 [pubmed] -PHST- 2011/08/17 06:00 [medline] -AID - BSP/CPD/E-Pub/000144 [pii] -AID - 10.2174/138161210792062830 [doi] -PST - ppublish -SO - Curr Pharm Des. 2010;16(23):2551-8. doi: 10.2174/138161210792062830. - -PMID- 20465103 -OWN - NLM -STAT- MEDLINE -DCOM- 20100601 -LR - 20100514 -IS - 0042-773X (Print) -IS - 0042-773X (Linking) -VI - 56 -IP - 4 -DP - 2010 Apr -TI - [Surgical treatment of ischemic heart disease and diabetes mellitus]. -PG - 317-9 -AB - At present, treatment of IHD is relatively frequently surgical. Approximately - every fourth patient undergoing surgery for IHD is a diabetic. The surgery itself - does not differ from non-diabetic patients except for the specific preparation of - a diabetic patient with respect to glycaemia control and with respect to - metabolic demands associated with the surgical intervention. Frequent involvement - of more extensive as well as more peripheral regions of the coronary arteries - makes the surgical intervention more difficult. The differences with respect to - mortality have been diminished mainly due to the continuously improving cardiac - surgery and expanding knowledge of pathophysiology of DM, enabling better control - and correction of glycaemia. However, the differences with respect to morbidity - still remain (higher incidence of wound healing problems, higher incidence of - strokes, renal failure, longer mean duration of hospitalization). Furthermore, - long-term survival in diabetic patients is shorter, particularly due to more - rapidly progressing atherosclerosis. The outcomes of IHD treatment in diabetic - patients might improve when these well-known issues are fully acknowledged. The - best possible diabetes treatment might contribute to this. Surgical treatment of - IHD, particularly arterial grafting and use of as gentle as possible approaches - (myocardial revascularization from mini-invasive entry pathways, possibly without - extracorporeal circulation) also encompass great potential for outcome - improvement. -FAU - Harrer, J -AU - Harrer J -AD - Kardiochirurgická klinika Lékarské fakulty UK a FN Hradec Králové. - jharrer@seznam.cz -FAU - Drasnar, A -AU - Drasnar A -FAU - Vojácek, J -AU - Vojácek J -LA - cze -PT - English Abstract -PT - Journal Article -PT - Review -TT - Chirurgická lécba isthemické thoroby srdecní a diabetes mellitus. -PL - Czech Republic -TA - Vnitr Lek -JT - Vnitrni lekarstvi -JID - 0413602 -SB - IM -MH - Diabetes Mellitus, Type 2/*complications -MH - Humans -MH - Myocardial Ischemia/complications/*surgery -MH - Postoperative Complications -MH - Preoperative Care -RF - 11 -EDAT- 2010/05/15 06:00 -MHDA- 2010/06/02 06:00 -CRDT- 2010/05/15 06:00 -PHST- 2010/05/15 06:00 [entrez] -PHST- 2010/05/15 06:00 [pubmed] -PHST- 2010/06/02 06:00 [medline] -PST - ppublish -SO - Vnitr Lek. 2010 Apr;56(4):317-9. - -PMID- 23888997 -OWN - NLM -STAT- MEDLINE -DCOM- 20140731 -LR - 20131122 -IS - 1440-1681 (Electronic) -IS - 0305-1870 (Linking) -VI - 40 -IP - 12 -DP - 2013 Dec -TI - Mineralocorticoid receptor and cardiac arrhythmia. -PG - 910-5 -LID - 10.1111/1440-1681.12156 [doi] -AB - Mineralocorticoid receptor (MR) activation has been shown to play a deleterious - role in the development of heart disease in studies using specific MR antagonists - (spironolactone, eplerenone) in both experimental models and patients. - Pharmacological MR blockade attenuates the transition to heart failure (HF) in - models of systolic left ventricular dysfunction and myocardial infarction, as - well as diastolic dysfunction, in rats and mice. In humans, MR antagonism is - highly beneficial in patients with mild or advanced HF and postinfarct HF. The - consequences of aldosterone and MR activation for cardiac arrhythmia and its - prevention and/or correction by MR antagonists are often underestimated. -  Activation of MR modulates cardiac electrical activity, causing atrial and - ventricular arrhythmias. A pro-arrhythmogenic effect of aldosterone (possibly - partly dependent on fibrosis) has been suggested by several studies. Cardiac MR - activation has important consequences for the control of cellular calcium - homeostasis, action potential lengthening, modulation of calcium transients and - sarcoplasmic reticulum diastolic leaks, resulting in the promotion of rhythm - disorders. Aldosterone and/or MR activation (in both cardiomyocytes and coronary - vessels) result in vascular dysfunction and also contribute to pro-arrhythmogenic - conditions.  Together, the pro-arrhythmic effects of aldosterone and/or MR may - explain the highly beneficial effect of MR antagonism, namely a decrease in the - incidence of sudden death, observed in the Randomized Aldactone Evaluation Study - (RALES) and Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy - and Survival Study (EPHESUS) studies. -CI - © 2013 Wiley Publishing Asia Pty Ltd. -FAU - Gravez, Basile -AU - Gravez B -AD - INSERM UMR 872 Team 1, Centre de Recherche des Cordeliers, University Pierre and - Marie Curie, Paris, France. -FAU - Tarjus, Antoine -AU - Tarjus A -FAU - Jaisser, Frederic -AU - Jaisser F -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Australia -TA - Clin Exp Pharmacol Physiol -JT - Clinical and experimental pharmacology & physiology -JID - 0425076 -RN - 0 (Mineralocorticoid Receptor Antagonists) -RN - 0 (Receptors, Mineralocorticoid) -RN - 4964P6T9RB (Aldosterone) -SB - IM -MH - Aldosterone/metabolism -MH - Animals -MH - Arrhythmias, Cardiac/complications/drug therapy/*metabolism/pathology -MH - Atrial Fibrillation/etiology/pathology/prevention & control -MH - Death, Sudden, Cardiac/etiology/pathology/prevention & control -MH - Fibrosis -MH - Humans -MH - Mineralocorticoid Receptor Antagonists/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Receptors, Mineralocorticoid/*metabolism -OTO - NOTNLM -OT - aldosterone -OT - arrhythmia -OT - cardiovascular disease -OT - mineralocorticoid receptors -EDAT- 2013/07/31 06:00 -MHDA- 2014/08/01 06:00 -CRDT- 2013/07/30 06:00 -PHST- 2013/04/24 00:00 [received] -PHST- 2013/07/15 00:00 [revised] -PHST- 2013/07/21 00:00 [accepted] -PHST- 2013/07/30 06:00 [entrez] -PHST- 2013/07/31 06:00 [pubmed] -PHST- 2014/08/01 06:00 [medline] -AID - 10.1111/1440-1681.12156 [doi] -PST - ppublish -SO - Clin Exp Pharmacol Physiol. 2013 Dec;40(12):910-5. doi: 10.1111/1440-1681.12156. - -PMID- 16732689 -OWN - NLM -STAT- MEDLINE -DCOM- 20060912 -LR - 20181113 -IS - 1170-229X (Print) -IS - 1170-229X (Linking) -VI - 23 -IP - 4 -DP - 2006 -TI - Diastolic heart failure in the elderly and the potential role of aldosterone - antagonists. -PG - 299-308 -AB - The overall incidence of heart failure increases with age, affecting up to 10% of - people >65 years of age. Diastolic heart failure is also age-dependent, - increasing from <15% in middle-aged patients to >40% in patients > or =70 years - of age. Elderly patients usually have other co-morbid conditions such as - hypertension, diabetes mellitus, coronary artery disease and atrial fibrillation - that can adversely affect the diastolic properties of the heart. The clinical - manifestations of diastolic heart failure are similar to those of systolic heart - failure. In practice, the diagnosis is generally based on the finding of typical - symptoms and signs of heart failure with preserved left ventricular ejection - fraction and no valvular abnormalities on echocardiography. Altered ventricular - relaxation and abnormal ventricular filling are the hallmarks of diastolic heart - failure. Cardiac fibrosis and cellular disarray lead to the alterations in the - diastolic properties of the heart. Diffuse foci of fibrosis in the myocardium - have been reported with advancing age. Aldosterone has been shown to play a - crucial role in the development of cardiac fibrosis via a direct effect on the - mineralocorticoid receptors within the myocardium. Unlike the situation with - treatment of systolic heart failure, few clinical trials are available to guide - the management of patients with diastolic heart failure. In the absence of - controlled clinical trials, patient management is based on control of the - physiological factors (blood pressure, heart rate, blood volume and myocardial - ischaemia) that are known to exert important effects on ventricular relaxation. - Aldosterone antagonists inhibit the deposition of collagen matrix in the - myocardium, thereby targeting the basic pathophysiological mechanism of diastolic - dysfunction. Thus, they appear to represent a promising therapeutic approach for - this condition. Currently, only small clinical trials supporting this therapy are - available and large clinical trials evaluating long-term outcomes in diastolic - dysfunction are therefore needed. -FAU - Kumar, Ashwani -AU - Kumar A -AD - Department of Internal Medicine, Texas Tech University Health Sciences Center, - Lubbock, USA. -FAU - Meyerrose, Gary -AU - Meyerrose G -FAU - Sood, Vineeta -AU - Sood V -FAU - Roongsritong, Chanwit -AU - Roongsritong C -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Drugs Aging -JT - Drugs & aging -JID - 9102074 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Mineralocorticoid Receptor Antagonists) -SB - IM -MH - Aged -MH - Aging -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Animals -MH - Clinical Trials as Topic -MH - *Diastole -MH - Drug Therapy, Combination -MH - Heart Failure/*drug therapy/*physiopathology -MH - Humans -MH - Mineralocorticoid Receptor Antagonists/*therapeutic use -RF - 57 -EDAT- 2006/05/31 09:00 -MHDA- 2006/09/13 09:00 -CRDT- 2006/05/31 09:00 -PHST- 2006/05/31 09:00 [pubmed] -PHST- 2006/09/13 09:00 [medline] -PHST- 2006/05/31 09:00 [entrez] -AID - 2343 [pii] -AID - 10.2165/00002512-200623040-00003 [doi] -PST - ppublish -SO - Drugs Aging. 2006;23(4):299-308. doi: 10.2165/00002512-200623040-00003. - -PMID- 17606856 -OWN - NLM -STAT- MEDLINE -DCOM- 20070720 -LR - 20220410 -IS - 1524-4539 (Electronic) -IS - 0009-7322 (Linking) -VI - 116 -IP - 1 -DP - 2007 Jul 3 -TI - Chronic kidney disease: effects on the cardiovascular system. -PG - 85-97 -AB - Accelerated cardiovascular disease is a frequent complication of renal disease. - Chronic kidney disease promotes hypertension and dyslipidemia, which in turn can - contribute to the progression of renal failure. Furthermore, diabetic nephropathy - is the leading cause of renal failure in developed countries. Together, - hypertension, dyslipidemia, and diabetes are major risk factors for the - development of endothelial dysfunction and progression of atherosclerosis. - Inflammatory mediators are often elevated and the renin-angiotensin system is - frequently activated in chronic kidney disease, which likely contributes through - enhanced production of reactive oxygen species to the accelerated atherosclerosis - observed in chronic kidney disease. Promoters of calcification are increased and - inhibitors of calcification are reduced, which favors metastatic vascular - calcification, an important participant in vascular injury associated with - end-stage renal disease. Accelerated atherosclerosis will then lead to increased - prevalence of coronary artery disease, heart failure, stroke, and peripheral - arterial disease. Consequently, subjects with chronic renal failure are exposed - to increased morbidity and mortality as a result of cardiovascular events. - Prevention and treatment of cardiovascular disease are major considerations in - the management of individuals with chronic kidney disease. -FAU - Schiffrin, Ernesto L -AU - Schiffrin EL -AD - Department of Medicine, Sir Mortimer B. Davis Jewish General Hospital, McGill - University, Montreal, Quebec, Canada. ernesto.schiffrin@mcgill.ca -FAU - Lipman, Mark L -AU - Lipman ML -FAU - Mann, Johannes F E -AU - Mann JF -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Circulation -JT - Circulation -JID - 0147763 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Biomarkers) -RN - 0 (CST3 protein, human) -RN - 0 (Cystatin C) -RN - 0 (Cystatins) -RN - 0 (Inflammation Mediators) -RN - 0 (Phosphates) -RN - 63CV1GEK3Y (N,N-dimethylarginine) -RN - 94ZLA3W45F (Arginine) -RN - AYI8EX34EU (Creatinine) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Albuminuria/epidemiology -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Animals -MH - Arginine/analogs & derivatives/metabolism -MH - Atherosclerosis/etiology/physiopathology -MH - Biomarkers -MH - Bone Resorption/etiology -MH - Calcinosis/etiology/physiopathology -MH - Calcium/metabolism -MH - Cardiovascular Diseases/epidemiology/*etiology/physiopathology/prevention & - control -MH - Chronic Disease -MH - Clinical Trials as Topic -MH - Cohort Studies -MH - Creatinine/blood -MH - Cystatin C -MH - Cystatins/blood -MH - Diabetes Complications/physiopathology -MH - Disease Progression -MH - Dogs -MH - Dyslipidemias/etiology -MH - Endothelium, Vascular/physiopathology -MH - Glomerular Filtration Rate -MH - Humans -MH - Hypertension, Renal/etiology -MH - Inflammation Mediators/metabolism -MH - Kidney Diseases/complications/epidemiology/*physiopathology -MH - Oxidative Stress -MH - Phosphates/metabolism -MH - Renin-Angiotensin System/physiology -MH - Risk Factors -RF - 124 -EDAT- 2007/07/04 09:00 -MHDA- 2007/07/21 09:00 -CRDT- 2007/07/04 09:00 -PHST- 2007/07/04 09:00 [pubmed] -PHST- 2007/07/21 09:00 [medline] -PHST- 2007/07/04 09:00 [entrez] -AID - 116/1/85 [pii] -AID - 10.1161/CIRCULATIONAHA.106.678342 [doi] -PST - ppublish -SO - Circulation. 2007 Jul 3;116(1):85-97. doi: 10.1161/CIRCULATIONAHA.106.678342. - -PMID- 38620511 -STAT- Publisher -CTDT- 20100401 -PB - Therapeutics Initiative -DP - 1994 -TI - Do statins have a role in primary prevention? An update. -BTI - Therapeutics Letter -CP - Letter 77 -AB - Therapeutics Letter 77 explores the role of statins in primary prevention using - Cochrane Collaboration methodology. Conclusions: Systematic reviews and - meta-analyses are challenging and require much more than locating RCTs and - plugging in the numbers. The claimed mortality benefit of statins for primary - prevention is more likely a measure of bias than a real effect. The reduction in - major CHD serious adverse events with statins as compared to placebo is not - reflected in a reduction in total serious adverse events. Statins do not have a - proven net health benefit in primary prevention populations and thus when used in - that setting do not represent good use of scarce health care resources. -CI - Copyright © 1994 - 2022 Therapeutics Initiative, University of British Columbia. -FED - Perry, Tom -ED - Perry T -LA - eng -PT - Review -PT - Book Chapter -PL - Vancouver (BC) -OTO - NLM -OT - Bias -OT - Coronary Disease -OT - Hydroxymethylglutaryl-CoA Reductase Inhibitors -OT - Mortality -OT - Primary Prevention -EDAT- 2010/04/01 00:00 -CRDT- 2010/04/01 00:00 -AID - NBK598530 [bookaccession] - -PMID- 17991195 -OWN - NLM -STAT- MEDLINE -DCOM- 20080201 -LR - 20131121 -IS - 0894-0959 (Print) -IS - 0894-0959 (Linking) -VI - 20 -IP - 6 -DP - 2007 Nov-Dec -TI - The cholesterol paradox is flawed; cholesterol must be lowered in dialysis - patients. -PG - 504-9 -AB - In the general population, elevated cholesterol is associated with cardiovascular - disease and mortality and lowering cholesterol is associated with improved - outcomes. This reflects the predominance of isolated atherosclerotic coronary - disease in the general population. In patients with renal disease, however, the - relationship between serum lipids and cardiovascular outcomes is much less clear - and even reversed. In our opinion, the relationship between cholesterol and - coronary disease is obscured by high levels of co-morbid disease, malnutrition, - inflammation, atypical dyslipidemia and the fact that myocardial infarction is - not the typical presentation of cardiovascular disease in patients with renal - disease. Thus, cholesterol lowering will still be effective in patients with - chronic kidney diseases. -FAU - Wan, Ray K -AU - Wan RK -AD - BHF Cardiovascular Research Centre, University of Glasgow, and Renal Transplant - Unit, Western Infirmary, Glasgow, United Kingdom. -FAU - Mark, Patrick B -AU - Mark PB -FAU - Jardine, Alan G -AU - Jardine AG -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Semin Dial -JT - Seminars in dialysis -JID - 8911629 -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Cardiovascular Diseases/blood/etiology -MH - Cholesterol/*blood -MH - Clinical Trials as Topic -MH - Dyslipidemias/complications/drug therapy -MH - Humans -MH - Hyperlipidemias/complications/drug therapy -MH - Inflammation/complications -MH - Kidney Failure, Chronic/blood/complications/therapy -MH - Malnutrition/complications -MH - Models, Cardiovascular -MH - *Renal Dialysis -MH - Risk Factors -RF - 52 -EDAT- 2007/11/10 09:00 -MHDA- 2008/02/02 09:00 -CRDT- 2007/11/10 09:00 -PHST- 2007/11/10 09:00 [pubmed] -PHST- 2008/02/02 09:00 [medline] -PHST- 2007/11/10 09:00 [entrez] -AID - SDI359 [pii] -AID - 10.1111/j.1525-139X.2007.00359.x [doi] -PST - ppublish -SO - Semin Dial. 2007 Nov-Dec;20(6):504-9. doi: 10.1111/j.1525-139X.2007.00359.x. - -PMID- 23088939 -OWN - NLM -STAT- MEDLINE -DCOM- 20130325 -LR - 20191210 -IS - 1535-6280 (Electronic) -IS - 0146-2806 (Linking) -VI - 37 -IP - 12 -DP - 2012 Dec -TI - Acute right ventricular infarction: insights for the interventional era. -PG - 533-57 -LID - S0146-2806(12)00081-3 [pii] -LID - 10.1016/j.cpcardiol.2012.05.001 [doi] -AB - Acute right ventricular infarction is associated with higher in-hospital - morbidity and mortality related to life-threatening hemodynamic compromise and - arrhythmias during acute occlusion and abruptly with reperfusion, complications - which have implications for interventional management. Acute right coronary - artery occlusion proximal to the right ventricular (RV) branches results in - depressed RV systolic function, leading to diminished transpulmonary delivery of - left ventricular preload and resulting in low-output hypotension. Under these - conditions, RV pressure generation and output are dependent on left - ventricular-septal contraction via paradoxical septal motion. With culprit - lesions distal to the right atrial (RA) branches, augmented RA contractility - enhances RV performance and cardiac output, whereas proximal occlusions induce RA - ischemia, which exacerbates hemodynamic compromise. Hypotension may respond to - volume resuscitation and restoration of a physiologic rhythm. Refractory cases - usually respond to parenteral inotropes, though in some cases mechanical support - is required. The right ventricle is relatively resistant to infarction and - usually recovers even after prolonged occlusion. Acute percutaneous mechanical - reperfusion enhances recovery of RV performance and improves the clinical course - and survival of patients with right ventricular infarction. -CI - Copyright © 2012 James Goldstein. Published by Mosby, Inc. All rights reserved. -FAU - Goldstein, James A -AU - Goldstein JA -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Curr Probl Cardiol -JT - Current problems in cardiology -JID - 7701802 -SB - IM -MH - Arrhythmias, Cardiac/etiology/physiopathology -MH - Cardiac Output, Low/etiology/physiopathology -MH - *Disease Management -MH - Heart Function Tests -MH - Heart Ventricles/pathology/physiopathology -MH - Hemodynamics -MH - Humans -MH - Hypotension/etiology/physiopathology -MH - Medication Therapy Management -MH - *Myocardial Infarction/complications/diagnosis/mortality/physiopathology/therapy -MH - Myocardial Reperfusion Injury/etiology/physiopathology -MH - Myocardial Revascularization/adverse effects/methods -MH - Outcome Assessment, Health Care -MH - Survival Analysis -MH - *Ventricular Dysfunction, Right/etiology/physiopathology -EDAT- 2012/10/24 06:00 -MHDA- 2013/03/26 06:00 -CRDT- 2012/10/24 06:00 -PHST- 2012/10/24 06:00 [entrez] -PHST- 2012/10/24 06:00 [pubmed] -PHST- 2013/03/26 06:00 [medline] -AID - S0146-2806(12)00081-3 [pii] -AID - 10.1016/j.cpcardiol.2012.05.001 [doi] -PST - ppublish -SO - Curr Probl Cardiol. 2012 Dec;37(12):533-57. doi: 10.1016/j.cpcardiol.2012.05.001. - -PMID- 17691956 -OWN - NLM -STAT- MEDLINE -DCOM- 20071113 -LR - 20220330 -IS - 0929-8673 (Print) -IS - 0929-8673 (Linking) -VI - 14 -IP - 20 -DP - 2007 -TI - The role of PDE5-inhibitors in cardiopulmonary disorders: from basic evidence to - clinical development. -PG - 2181-91 -AB - Phosphodiesterases (PDE) are a class of proteins whose most relevant biological - activity concerns the modulation of intracellular levels of cyclic nucleotides, - e.g., cGMP and cAMP. PDE isoenzyme 5 (PDE5) is specifically involved in cGMP - inactivation in the smooth muscle cell. Chemical inhibition of PDE5 by - sildenafil, tadalafil or vardenafil recently became a valid therapeutic option - aimed at overexpressing the molecular pathway originated from nitric oxide and - expressed via increased cell cGMP availability. Based on the optimal tolerability - and proven efficacy in various human disorders, EMEA and FDA have approved PDE5 - inhibition as an efficient therapy in some cardiovascular, pulmonary and vascular - diseases. More specifically, PDE5 inhibition appears successful for the treatment - of idiopathic arterial pulmonary hypertension. Furthermore, PDE5 inhibition - resulted in important protective effects in the myocardium, i.e., - antyhypertrophic and antiapoptic, as well as vascular functions, i.e., increased - tolerance to ischemia/reperfusion injury and improved endothelial function, - thereby implying a potential usefulness in the treatment of patients with heart - failure and coronary artery disease. Evidence currently available for considering - PDE5-inhibition an additional opportunity in the treatment of common - cardiopulmonary disorders is here provided. -FAU - Guazzi, Marco -AU - Guazzi M -AD - Department of Medicine, Surgery and Dentistry, University of Milan, San Paolo - Hospital, Milan, Italy. Marco.Guazzi@unimi.it -FAU - Samaja, Michele -AU - Samaja M -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Enzyme Inhibitors) -RN - EC 3.1.4.35 (3',5'-Cyclic-GMP Phosphodiesterases) -RN - EC 3.1.4.35 (Cyclic Nucleotide Phosphodiesterases, Type 5) -RN - EC 3.1.4.35 (PDE5A protein, human) -SB - IM -MH - 3',5'-Cyclic-GMP Phosphodiesterases/*antagonists & - inhibitors/chemistry/*metabolism -MH - Cyclic Nucleotide Phosphodiesterases, Type 5 -MH - Enzyme Inhibitors/*chemistry/*pharmacology/therapeutic use -MH - Heart Diseases/drug therapy/*enzymology -MH - Humans -MH - Lung Diseases/drug therapy/*enzymology -RF - 150 -EDAT- 2007/08/19 09:00 -MHDA- 2007/11/14 09:00 -CRDT- 2007/08/19 09:00 -PHST- 2007/08/19 09:00 [pubmed] -PHST- 2007/11/14 09:00 [medline] -PHST- 2007/08/19 09:00 [entrez] -AID - 10.2174/092986707781389619 [doi] -PST - ppublish -SO - Curr Med Chem. 2007;14(20):2181-91. doi: 10.2174/092986707781389619. - -PMID- 20934658 -OWN - NLM -STAT- MEDLINE -DCOM- 20110210 -LR - 20101011 -IS - 1878-0938 (Electronic) -IS - 1878-0938 (Linking) -VI - 11 -IP - 4 -DP - 2010 Oct-Dec -TI - Remodeling of the mitral valve using radiofrequency energy: review of a new - treatment modality for mitral regurgitation. -PG - 249-59 -LID - 10.1016/j.carrev.2009.10.004 [doi] -AB - Mitral regurgitation (MR) is a common valvular pathology with significant - morbidity and mortality implications. Mechanical treatment of this condition is - more effective than medical treatment and surgical correction has traditionally - been the mechanical method of choice. Following major advances and wide - acceptance of percutaneous interventions for coronary artery diseases, the field - of valvular heart disease became an attractive target for transcatheter treatment - modalities. Significant steps have been achieved in the field of percutaneous - treatment of mitral stenosis as well as aortic stenosis, and lately, mitral - regurgitation has been the focus of interest for many investigators looking for - transcatheter solutions. Percutaneous edge-to-edge techniques and annuloplasty - are innovative but have many disadvantages including the inability to reintervene - and leaving a foreign body behind, respectively. Since the mitral and tricuspid - annuli have dense collagen, a treatment modality targeting that collagen is - logical. Observing the thermal effect on collagen, which causes conformational - changes and shrinkage, radiofrequency energy was tested to evaluate its effect on - the collagen-rich structure that is the mitral valve annulus. The potential of - shrinking the mitral annulus by applying direct thermal source could be a - promising modality for the treatment of mitral regurgitation with potential open - and percutaneous applications. This paper presents an overview of the recent - advances in transcatheter treatment of mitral regurgitation focusing on a new - treatment modality that aims at reducing the mitral valve annulus diameter - through the direct application of thermal energy using a radiofrequency energy - probe. -CI - Copyright © 2010 Elsevier Inc. All rights reserved. -FAU - Rahman, Sam -AU - Rahman S -AD - University of Arizona/Sarver Heart Center, Tucson, AZ, USA. -FAU - Eid, Nadia -AU - Eid N -FAU - Murarka, Shishir -AU - Murarka S -FAU - Heuser, Richard R -AU - Heuser RR -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Cardiovasc Revasc Med -JT - Cardiovascular revascularization medicine : including molecular interventions -JID - 101238551 -RN - 9007-34-5 (Collagen) -SB - IM -MH - Animals -MH - *Cardiac Surgical Procedures/instrumentation -MH - *Catheter Ablation/instrumentation -MH - Collagen/metabolism -MH - Equipment Design -MH - Humans -MH - Mitral Valve/metabolism/pathology/*surgery -MH - Mitral Valve Insufficiency/metabolism/pathology/*surgery -MH - Treatment Outcome -EDAT- 2010/10/12 06:00 -MHDA- 2011/02/11 06:00 -CRDT- 2010/10/12 06:00 -PHST- 2009/05/06 00:00 [received] -PHST- 2009/10/16 00:00 [revised] -PHST- 2009/10/26 00:00 [accepted] -PHST- 2010/10/12 06:00 [entrez] -PHST- 2010/10/12 06:00 [pubmed] -PHST- 2011/02/11 06:00 [medline] -AID - S1553-8389(09)00292-9 [pii] -AID - 10.1016/j.carrev.2009.10.004 [doi] -PST - ppublish -SO - Cardiovasc Revasc Med. 2010 Oct-Dec;11(4):249-59. doi: - 10.1016/j.carrev.2009.10.004. - -PMID- 24251031 -OWN - NLM -STAT- PubMed-not-MEDLINE -DCOM- 20140624 -LR - 20211021 -IS - 2072-1439 (Print) -IS - 2077-6624 (Electronic) -IS - 2072-1439 (Linking) -VI - 5 Suppl 6 -IP - Suppl 6 -DP - 2013 Nov -TI - Minimally invasive surgery for atrial fibrillation. -PG - S704-12 -LID - 10.3978/j.issn.2072-1439.2013.10.17 [doi] -AB - Atrial fibrillation (AF) remains the most common cardiac arrhythmia, affecting - nearly 2% of the general population worldwide. Minimally invasive surgical - ablation remains one of the most dynamically evolving fields of modern cardiac - surgery. While there are more than a dozen issues driving this development, two - seem to play the most important role: first, there is lack of evidence supporting - percutaneous catheter based approach to treat patients with persistent and - long-standing persistent AF. Paucity of this data offers surgical community - unparalleled opportunity to challenge guidelines and change indications for - surgical intervention. Large, multicenter prospective clinical studies are - therefore of utmost importance, as well as honest, clear data reporting. Second, - a collaborative methodology started a long-awaited debate on a Heart Team - approach to AF, similar to the debate on coronary artery disease and - transcatheter valves. Appropriate patient selection and tailored treatment - options will most certainly result in better outcomes and patient satisfaction, - coupled with appropriate use of always-limited institutional resources. The aim - of this review, unlike other reviews of minimally invasive surgical ablation, is - to present medical professionals with two distinctly different, approaches. The - first one is purely surgical, Standalone surgical isolation of the pulmonary - veins using bipolar energy source with concomitant amputation of the left atrial - appendage-a method of choice in one of the most important clinical trials on - AF-The Atrial Fibrillation Catheter Ablation Versus Surgical Ablation Treatment - (FAST) Trial. The second one represents the most complex approach to this - problem: a multidisciplinary, combined effort of a cardiac surgeon and - electrophysiologist. The Convergent Procedure, which includes both endocardial - and epicardial unipolar ablation bonds together minimally invasive endoscopic - surgery with electroanatomical mapping, to deliver best of the two worlds. One - goal remains: to help those in urgent need for everlasting relief. -FAU - Zembala, Michael O -AU - Zembala MO -AD - Department of Cardiothoracic Surgery and Transplantology, Silesian Center for - Heart Diseases Zabrze, Poland; -FAU - Suwalski, Piotr -AU - Suwalski P -LA - eng -PT - Journal Article -PT - Review -PL - China -TA - J Thorac Dis -JT - Journal of thoracic disease -JID - 101533916 -PMC - PMC3831834 -OTO - NOTNLM -OT - Ablation -OT - Atrial Fibrillation -OT - Minimally invasive surgery -EDAT- 2013/11/20 06:00 -MHDA- 2013/11/20 06:01 -PMCR- 2013/11/01 -CRDT- 2013/11/20 06:00 -PHST- 2013/10/18 00:00 [received] -PHST- 2013/10/26 00:00 [accepted] -PHST- 2013/11/20 06:00 [entrez] -PHST- 2013/11/20 06:00 [pubmed] -PHST- 2013/11/20 06:01 [medline] -PHST- 2013/11/01 00:00 [pmc-release] -AID - jtd-05-S6-S704 [pii] -AID - 10.3978/j.issn.2072-1439.2013.10.17 [doi] -PST - ppublish -SO - J Thorac Dis. 2013 Nov;5 Suppl 6(Suppl 6):S704-12. doi: - 10.3978/j.issn.2072-1439.2013.10.17. - -PMID- 20797981 -OWN - NLM -STAT- MEDLINE -DCOM- 20111128 -LR - 20101115 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 31 -IP - 22 -DP - 2010 Nov -TI - Three-dimensional imaging in the context of minimally invasive and transcatheter - cardiovascular interventions using multi-detector computed tomography: from - pre-operative planning to intra-operative guidance. -PG - 2727-40 -LID - 10.1093/eurheartj/ehq302 [doi] -AB - The rapid expansion of less invasive surgical and transcatheter cardiovascular - procedures for a wide range of cardiovascular conditions, including coronary, - valvular, structural cardiac, and aortic disease has been paralleled by novel - three-dimensional (3-D) approaches to imaging. Three-dimensional imaging allows - acquisition of volumetric data sets and subsequent off-line reconstructions along - unlimited 2-D planes and 3-D volumes. Pre-procedural 3-D imaging provides - detailed understanding of the operative field for surgical/interventional - planning. Integration of imaging modalities during the procedure allows real-time - guidance. Because computed tomography routinely acquires 3-D data sets, it has - been one of the early imaging modalities applied in the context of surgical and - interventional planning. This review describes the continuum of applications from - pre-operative planning to procedural integration, based on the emerging - experience with computed tomography and rotational angiography, respectively. At - the same time, the potential adverse effects of imaging with X-ray-based - tomographic or angiographic modalities are discussed. It is emphasized that the - role of imaging guidance in this context remains unclear and will need to be - evaluated in clinical trials. This is in particular true, because data showing - improved outcome or even non-inferiority for most of the emerging transcatheter - procedures are still lacking. -FAU - Schoenhagen, Paul -AU - Schoenhagen P -AD - Imaging Institute, Cleveland Clinic, Desk J-1 4, 9500 Euclid Avenue, Cleveland, - OH, USA. schoenp1@ccf.org -FAU - Numburi, Uma -AU - Numburi U -FAU - Halliburton, Sandra S -AU - Halliburton SS -FAU - Aulbach, Peter -AU - Aulbach P -FAU - von Roden, Martin -AU - von Roden M -FAU - Desai, Milind Y -AU - Desai MY -FAU - Rodriguez, Leonardo L -AU - Rodriguez LL -FAU - Kapadia, Samir R -AU - Kapadia SR -FAU - Tuzcu, E Murat -AU - Tuzcu EM -FAU - Lytle, Bruce W -AU - Lytle BW -LA - eng -PT - Journal Article -PT - Review -DEP - 20100825 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -SB - IM -MH - Catheter Ablation/*methods -MH - Electrocardiography -MH - Heart Diseases/*surgery -MH - Humans -MH - Imaging, Three-Dimensional -MH - Intraoperative Care/methods -MH - Patient Care Planning -MH - Preoperative Care/methods -MH - Radiography, Interventional/methods -MH - Stents -MH - Tomography, X-Ray Computed/*methods -EDAT- 2010/08/28 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2010/08/28 06:00 -PHST- 2010/08/28 06:00 [entrez] -PHST- 2010/08/28 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -AID - ehq302 [pii] -AID - 10.1093/eurheartj/ehq302 [doi] -PST - ppublish -SO - Eur Heart J. 2010 Nov;31(22):2727-40. doi: 10.1093/eurheartj/ehq302. Epub 2010 - Aug 25. - -PMID- 18827085 -OWN - NLM -STAT- MEDLINE -DCOM- 20090109 -LR - 20101118 -IS - 0279-5442 (Print) -IS - 0279-5442 (Linking) -VI - 28 -IP - 5 -DP - 2008 Oct -TI - Management of patients after percutaneous coronary interventions. -PG - 26-41; quiz 42 -FAU - Shoulders-Odom, Bridget -AU - Shoulders-Odom B -AD - Tampa VA Hospital, Tampa, Florida, USA. Bso1029@aol.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Crit Care Nurse -JT - Critical care nurse -JID - 8207799 -MH - Aneurysm, False/etiology/prevention & control -MH - Angioplasty, Balloon, Coronary/adverse effects/methods/*nursing -MH - Arteriovenous Fistula/etiology/prevention & control -MH - Coronary Restenosis/etiology/prevention & control -MH - Critical Care/*methods -MH - Critical Pathways/organization & administration -MH - Electrocardiography -MH - Family/psychology -MH - Hematoma/etiology/prevention & control -MH - Hemostasis, Surgical/methods/nursing -MH - Humans -MH - Monitoring, Physiologic/methods/nursing -MH - Nursing Assessment -MH - Patient Care Planning -MH - Patient Discharge -MH - Patient Education as Topic -MH - *Postoperative Care/methods/nursing -MH - Practice Guidelines as Topic -MH - Risk Factors -MH - Stents/adverse effects -MH - Thromboembolism/etiology/prevention & control -RF - 34 -EDAT- 2008/10/02 09:00 -MHDA- 2009/01/10 09:00 -CRDT- 2008/10/02 09:00 -PHST- 2008/10/02 09:00 [pubmed] -PHST- 2009/01/10 09:00 [medline] -PHST- 2008/10/02 09:00 [entrez] -AID - 28/5/26 [pii] -PST - ppublish -SO - Crit Care Nurse. 2008 Oct;28(5):26-41; quiz 42. - -PMID- 19859044 -OWN - NLM -STAT- MEDLINE -DCOM- 20100326 -LR - 20161125 -IS - 0391-1977 (Print) -IS - 0391-1977 (Linking) -VI - 34 -IP - 3 -DP - 2009 Sep -TI - Cardiovascular risk stratification of diabetic patients. -PG - 205-21 -AB - Diabetes mellitus is a complex clinical entity that will grow in importance in - the future. The complications of diabetes have a significant impact on patient - survival and quality of life, particularly with respect to coronary artery - disease (CAD). Appropriate screening and aggressive intervention can - significantly benefit many patients with diabetes. In addition, it is important - to consider strategies useful not only in the diagnosis of CAD but also in the - prognostic evaluation of diabetic patients with coronary disease. Prognostic data - are essential in defining risk categories and to apply appropriate treatment for - the degree of risk. Therefore, accurate cardiovascular risk stratification of - patients with type 2 diabetes is required. However, this can be a problematic - issue because the clinical presentation and progression of CAD differs between - diabetic and nondiabetic subjects. In addition to a higher prevalence of CAD, - patients with diabetes experience more diffuse and extensive coronary artery - involvement, more often have left ventricular dysfunction, a more advanced - coronary disease at the time of diagnosis, and more often experience silent - ischemia. Furthermore, diabetic patients have frequently a less favorable - response to revascularization procedures and a poorer long-term outcome. The - purpose of this review is to discuss the relative role of various procedures for - diagnosis of CAD and for cardiac risk stratification in patients with diabetes. -FAU - Cuocolo, A -AU - Cuocolo A -AD - Department of Biomorphological and Functional Sciences, University Federico II, - Naples, Italy. cuocolo@unina.it -FAU - Concilio, C -AU - Concilio C -FAU - Acampa, W -AU - Acampa W -FAU - Ferro, A -AU - Ferro A -FAU - Evangelista, L -AU - Evangelista L -FAU - Daniele, S -AU - Daniele S -FAU - Petretta, M -AU - Petretta M -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Minerva Endocrinol -JT - Minerva endocrinologica -JID - 8406505 -SB - IM -MH - Cardiovascular Diseases/diagnosis/diagnostic imaging/*epidemiology -MH - Diabetic Angiopathies/diagnosis/diagnostic imaging/*epidemiology -MH - Humans -MH - Predictive Value of Tests -MH - Prognosis -MH - Radionuclide Imaging -MH - Risk Assessment -RF - 89 -EDAT- 2009/10/28 06:00 -MHDA- 2010/03/27 06:00 -CRDT- 2009/10/28 06:00 -PHST- 2009/10/28 06:00 [entrez] -PHST- 2009/10/28 06:00 [pubmed] -PHST- 2010/03/27 06:00 [medline] -AID - R07091725 [pii] -PST - ppublish -SO - Minerva Endocrinol. 2009 Sep;34(3):205-21. - -PMID- 21809306 -OWN - NLM -STAT- MEDLINE -DCOM- 20111123 -LR - 20161125 -IS - 0393-5590 (Print) -IS - 0393-5590 (Linking) -VI - 28 -IP - 4 -DP - 2011 Jul-Aug -TI - [LCAT deficiency: a nephrological diagnosis]. -PG - 369-82 -AB - A genetic mendelian autosomal recessive condition of deficiency of lecithin- - cholesterol acyltransferase (LCAT) can produce two different diseases: one highly - interesting nephrologic picture of complete enzymatic deficiency - (lecithin:cholesterol acyltransferase deficiency; OMIM ID #245900; FLD), - characterized by the association of dyslipidemia, corneal opacities, anemia and - progressive nephropathy; and a partial form (fish eye disease; OMIM ID #136120; - FED) with dyslipidemia and progressive corneal opacities only. The diagnosis of - FLD falls first of all under the competence of nephrologists, because end-stage - renal disease appears to be its most severe outcome. The diagnostic suspicion is - based on clinical signs (corneal opacities, more severe anemia than expected for - the degree of chronic renal failure, progressive proteinuric nephropathy) - combined with histology obtained by kidney biopsy (glomerulopathy evolving toward - sclerosis with distinctive lipid deposition). However, the final diagnosis, - starting with a finding of extremely low levels of HDL-cholesterol, requires - collaboration with lipidology Centers that can perform sophisticated - investigations unavailable in common laboratories. To be heterozygous for a - mutation of the LCAT gene is one of the monogenic conditions underlying primary - hypoalphalipoproteinemia (OMIM ID #604091). This disease, which is characterized - by levels of HDL-cholesterol below the 5th percentile of those of the examined - population (<28 mg/dL for Italians), has heritability estimates between 40% and - 60% and is considered to be a predisposing condition for coronary artery disease. - Nevertheless, some monogenic forms, and especially those associated with LCAT - deficiency, seem to break the rule, confirming once more the value of a proper - diagnosis before drawing prognostic conclusions from a laboratory marker. As in - many other rare illnesses, trying to discover all the existing cases will - contribute to allow studies broad enough to pave the way for further therapies, - in this case also fostering the production by industries of the lacking enzyme by - genetic engineering. Epidemiological studies, although done on selected - populations such as hypoalphalipoproteinemia patients on dialysis and with the - effective genetic tools of today, have been disappointing in elucidating the - disease. Spreading the clinical knowledge of the disease and its diagnostic - course among nephrologists seems to be the best choice, and this is the aim of - our work. -FAU - Boscutti, Giuliano -AU - Boscutti G -AD - SOC di Nefrologia e Dialisi, ASS2 Isontina Ospedale S. Giovanni di Dio, Gorizia, - Italy. guiliano.boscutti@ass2.sanita.fvg.it -FAU - Calabresi, Laura -AU - Calabresi L -FAU - Pizzolitto, Stefano -AU - Pizzolitto S -FAU - Boer, Emanuela -AU - Boer E -FAU - Bosco, Manuela -AU - Bosco M -FAU - Mattei, Piero Luigi -AU - Mattei PL -FAU - Martone, Massimiliano -AU - Martone M -FAU - Milutinovic, Neva -AU - Milutinovic N -FAU - Berbecar, Dorina -AU - Berbecar D -FAU - Beltram, Elisabetta -AU - Beltram E -FAU - Franceschini, Guido -AU - Franceschini G -LA - ita -PT - Journal Article -PT - Review -TT - Il deficit di LCAT: una diagnosi nefrologica. -PL - Italy -TA - G Ital Nefrol -JT - Giornale italiano di nefrologia : organo ufficiale della Societa italiana di - nefrologia -JID - 9426434 -RN - 0 (Biomarkers) -RN - 0 (Cholesterol, HDL) -RN - EC 2.3.1.43 (Phosphatidylcholine-Sterol O-Acyltransferase) -SB - IM -MH - Anemia/etiology -MH - Biomarkers/blood -MH - Biopsy -MH - Cholesterol, HDL/*blood/metabolism -MH - Corneal Opacity/etiology -MH - Coronary Artery Disease/prevention & control -MH - Disease Progression -MH - Dyslipidemias/etiology -MH - Genetic Engineering -MH - Heterozygote -MH - Humans -MH - Italy/epidemiology -MH - Kidney Diseases/*diagnosis/enzymology/*genetics/pathology/therapy -MH - Kidney Failure, Chronic/genetics/pathology -MH - Lecithin Cholesterol Acyltransferase - Deficiency/complications/*diagnosis/enzymology/epidemiology/*genetics/therapy -MH - Mutation -MH - Phosphatidylcholine-Sterol O-Acyltransferase/*genetics -MH - Proteinuria/etiology -MH - Risk Factors -MH - Treatment Outcome -EDAT- 2011/08/03 06:00 -MHDA- 2011/12/13 00:00 -CRDT- 2011/08/03 06:00 -PHST- 2011/08/03 06:00 [entrez] -PHST- 2011/08/03 06:00 [pubmed] -PHST- 2011/12/13 00:00 [medline] -PST - ppublish -SO - G Ital Nefrol. 2011 Jul-Aug;28(4):369-82. - -PMID- 18579034 -OWN - NLM -STAT- MEDLINE -DCOM- 20081003 -LR - 20190823 -IS - 0025-7753 (Print) -IS - 0025-7753 (Linking) -VI - 130 -IP - 20 -DP - 2008 May 31 -TI - [Apolipoprotein A5 gene: association with triglyceride metabolism and - cardiovascular disease]. -PG - 787-93 -AB - Hypertriglyceridemia constitutes an independent risk factor for coronary disease. - The gene apolipoprotein A5 (ApoA5) is a newly discovered member in the - ApoA1/C3/A4/A5 cluster, and its product, apolipoprotein A5, influences on - triglycerides through an unknown mechanism. Recently, there have been described - the clinical consequences and the functional effects over more than 10 variants - of the ApoA5 gene, associated with atherosclerosis. In different studies carried - out in different ethnic groups, it has been observed a great variation in the - distribution of the ApoA5 genotypes for the respective polymorphisms. Different - authors have described associations among the ApoA5 gene, high triglyceride - concentrations and an increase in the cardiovascular risk. In this context, the - ApoA5 gene is considered as a probable biochemical and genetic marker of - increased triglyceride concentrations and also a risk factor of coronary disease - in some populations. -FAU - Oliveira Sousa, Marinez -AU - Oliveira Sousa M -AD - Departamento de Análises Clínicas e Toxicológicas, Facultade de Farmacia, - Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. - marinez@farmacia.ufmg.br -FAU - Alía, Pedro -AU - Alía P -FAU - Pintó, Xavier -AU - Pintó X -LA - spa -PT - Journal Article -PT - Review -TT - Gen de la apolipoproteína A5: asociación con el metabolismo de los triglicéridos - y las enfermedades cardiovasculares. -PL - Spain -TA - Med Clin (Barc) -JT - Medicina clinica -JID - 0376377 -RN - 0 (APOA5 protein, human) -RN - 0 (Apolipoprotein A-V) -RN - 0 (Apolipoproteins A) -RN - 0 (Triglycerides) -SB - IM -MH - Alleles -MH - Apolipoprotein A-V -MH - Apolipoproteins A/*genetics -MH - Cardiovascular Diseases/*genetics/*metabolism -MH - Humans -MH - Hypertriglyceridemia/genetics -MH - Polymorphism, Genetic -MH - Triglycerides/*metabolism -RF - 67 -EDAT- 2008/06/27 09:00 -MHDA- 2008/10/04 09:00 -CRDT- 2008/06/27 09:00 -PHST- 2008/06/27 09:00 [pubmed] -PHST- 2008/10/04 09:00 [medline] -PHST- 2008/06/27 09:00 [entrez] -AID - S0025-7753(08)71578-1 [pii] -AID - 10.1157/13121105 [doi] -PST - ppublish -SO - Med Clin (Barc). 2008 May 31;130(20):787-93. doi: 10.1157/13121105. - -PMID- 24012155 -OWN - NLM -STAT- MEDLINE -DCOM- 20140824 -LR - 20131216 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 170 -IP - 2 Suppl 1 -DP - 2013 Dec 20 -TI - Re-assessing the mechanism of action of n-3 PUFAs. -PG - S8-11 -LID - S0167-5273(13)01092-9 [pii] -LID - 10.1016/j.ijcard.2013.06.038 [doi] -AB - Recent evidence has been accumulated showing that use of dietary n-3 - polyunsaturated fatty acids (n-3 PUFAs) produces significant benefits in - counteracting many disease states, including coronary atherosclerosis, fatal - arrhythmias and heart failure. Besides the mass of proposed pathophysiological - mechanisms underlying the potential benefits of using n-3 PUFAs, identification - of clear molecular targets or an appropriate dosing strategy for these compounds - still remain to be better elucidated. On the other hand, whilst n-3 PUFAs have - shown promise in all of these areas, results arising from clinical trials and - 'real-world' evidence sometimes appear controversial. Here we report on recent - advances in molecular targets identified for better assessment of the mode of - action of these interesting compounds. In addition, some appealing hypotheses of - their antioxidant properties will be discussed for better characterisation of - their mode of action and potential use in health and disease. -CI - © 2013. -FAU - Mollace, Vincenzo -AU - Mollace V -AD - Interregional Research Center for Food Safety & Health (IRC-FSH), University - Magna Graecia of Catanzaro, Catanzaro, Italy; IRCCS San Raffaele, Rome, Italy. - Electronic address: mollace@libero.it. -FAU - Gliozzi, Micaela -AU - Gliozzi M -AD - Interregional Research Center for Food Safety & Health (IRC-FSH), University - Magna Graecia of Catanzaro, Catanzaro, Italy. -FAU - Carresi, Cristina -AU - Carresi C -AD - Interregional Research Center for Food Safety & Health (IRC-FSH), University - Magna Graecia of Catanzaro, Catanzaro, Italy. -FAU - Musolino, Vincenzo -AU - Musolino V -AD - Interregional Research Center for Food Safety & Health (IRC-FSH), University - Magna Graecia of Catanzaro, Catanzaro, Italy. -FAU - Oppedisano, Francesca -AU - Oppedisano F -AD - Interregional Research Center for Food Safety & Health (IRC-FSH), University - Magna Graecia of Catanzaro, Catanzaro, Italy. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130906 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Antioxidants) -RN - 0 (Fatty Acids, Omega-3) -SB - IM -MH - Animals -MH - Anti-Inflammatory Agents/administration & dosage/metabolism -MH - Antioxidants/administration & dosage/metabolism -MH - Cardiovascular Diseases/*diet therapy/*metabolism/prevention & control -MH - Cell Membrane/metabolism -MH - Fatty Acids, Omega-3/*administration & dosage/*metabolism -MH - Humans -OTO - NOTNLM -OT - 4-Hydroxyhexenal -OT - Cardioprotection -OT - Free radicals -OT - Lipoxidative processes -OT - Oxidative stress -OT - PUFA-3 -EDAT- 2013/09/10 06:00 -MHDA- 2014/08/26 06:00 -CRDT- 2013/09/10 06:00 -PHST- 2013/09/10 06:00 [entrez] -PHST- 2013/09/10 06:00 [pubmed] -PHST- 2014/08/26 06:00 [medline] -AID - S0167-5273(13)01092-9 [pii] -AID - 10.1016/j.ijcard.2013.06.038 [doi] -PST - ppublish -SO - Int J Cardiol. 2013 Dec 20;170(2 Suppl 1):S8-11. doi: - 10.1016/j.ijcard.2013.06.038. Epub 2013 Sep 6. - -PMID- 23674795 -OWN - NLM -STAT- MEDLINE -DCOM- 20131202 -LR - 20230216 -IS - 2156-5376 (Electronic) -IS - 2161-8313 (Print) -IS - 2161-8313 (Linking) -VI - 4 -IP - 3 -DP - 2013 May 1 -TI - Dietary fats and health: dietary recommendations in the context of scientific - evidence. -PG - 294-302 -LID - 10.3945/an.113.003657 [doi] -AB - Although early studies showed that saturated fat diets with very low levels of - PUFAs increase serum cholesterol, whereas other studies showed high serum - cholesterol increased the risk of coronary artery disease (CAD), the evidence of - dietary saturated fats increasing CAD or causing premature death was weak. Over - the years, data revealed that dietary saturated fatty acids (SFAs) are not - associated with CAD and other adverse health effects or at worst are weakly - associated in some analyses when other contributing factors may be overlooked. - Several recent analyses indicate that SFAs, particularly in dairy products and - coconut oil, can improve health. The evidence of ω6 polyunsaturated fatty acids - (PUFAs) promoting inflammation and augmenting many diseases continues to grow, - whereas ω3 PUFAs seem to counter these adverse effects. The replacement of - saturated fats in the diet with carbohydrates, especially sugars, has resulted in - increased obesity and its associated health complications. Well-established - mechanisms have been proposed for the adverse health effects of some alternative - or replacement nutrients, such as simple carbohydrates and PUFAs. The focus on - dietary manipulation of serum cholesterol may be moot in view of numerous other - factors that increase the risk of heart disease. The adverse health effects that - have been associated with saturated fats in the past are most likely due to - factors other than SFAs, which are discussed here. This review calls for a - rational reevaluation of existing dietary recommendations that focus on - minimizing dietary SFAs, for which mechanisms for adverse health effects are - lacking. -FAU - Lawrence, Glen D -AU - Lawrence GD -AD - Department of Chemistry and Biochemistry, Long Island University, Brooklyn, NY, - USA. lawrence@liu.edu -LA - eng -PT - Journal Article -PT - Review -DEP - 20130501 -PL - United States -TA - Adv Nutr -JT - Advances in nutrition (Bethesda, Md.) -JID - 101540874 -RN - 0 (Dietary Fats) -RN - 0 (Fatty Acids) -RN - 0 (Fatty Acids, Unsaturated) -RN - 0 (Sweetening Agents) -RN - 30237-26-4 (Fructose) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Atherosclerosis/complications -MH - Cardiovascular Diseases/complications -MH - Cholesterol/blood/genetics -MH - *Diet -MH - Dietary Fats/*adverse effects -MH - Fatty Acids/*adverse effects -MH - Fatty Acids, Unsaturated/adverse effects -MH - Fructose/adverse effects -MH - Humans -MH - Lipid Peroxidation/physiology -MH - Sweetening Agents/adverse effects -PMC - PMC3650498 -COIS- Author disclosure: G. D. Lawrence, no conflicts of interest. -EDAT- 2013/05/16 06:00 -MHDA- 2013/12/16 06:00 -PMCR- 2014/05/01 -CRDT- 2013/05/16 06:00 -PHST- 2013/05/16 06:00 [entrez] -PHST- 2013/05/16 06:00 [pubmed] -PHST- 2013/12/16 06:00 [medline] -PHST- 2014/05/01 00:00 [pmc-release] -AID - S2161-8313(22)01116-4 [pii] -AID - 003657 [pii] -AID - 10.3945/an.113.003657 [doi] -PST - epublish -SO - Adv Nutr. 2013 May 1;4(3):294-302. doi: 10.3945/an.113.003657. - -PMID- 23123148 -OWN - NLM -STAT- MEDLINE -DCOM- 20130513 -LR - 20121203 -IS - 1590-3729 (Electronic) -IS - 0939-4753 (Linking) -VI - 22 -IP - 12 -DP - 2012 Dec -TI - Cardiovascular disease prevention in women: a rapidly evolving scenario. -PG - 1013-8 -LID - S0939-4753(12)00223-2 [pii] -LID - 10.1016/j.numecd.2012.10.001 [doi] -AB - The past decade has witnessed a long overdue recognition of the importance of CVD - in women, accompanied by an increasing awareness of gender differences in risk - factors, natural history, preventive strategies, treatment, and prognosis of CVD. - Reflecting the disease burden and the specific aspects of CVD in women, the - American Heart Association has developed women-specific evidence-based guidelines - and consensus documents for CVD prevention. The most recent update of these - guidelines, published in 2011, is a milestone in the field and shows the rapidly - evolving scenario of CVD prevention in women. We discuss some novel aspects of - the 2011 update. The new guidelines change the focus from evidence-based to - effectiveness-based, with consideration of both benefits and harms/costs of - preventive interventions. The guidelines also introduce "ideal cardiovascular - health" as the lowest category of risk, which implies the need of communitywide - preventive, educational and policy initiatives to promote healthy lifestyles in - the general population. Furthermore, the guidelines emphasize long-term overall - CVD risk rather than short-term coronary risk. We also address several barriers - and open questions in the evaluation and implementation of these guidelines, - including how to increase the small proportion of women with ideal cardiovascular - health; how to increase implementation and compliance with the recommendations; - how to provide effectiveness-based recommendations for lifetime prevention goals - based on short-term trials; how to obtain the best possible evidence in women; - how to identify subgroups of women with different cardiovascular risk profiles or - who may require tailored preventive strategies; and how to adapt current - guidelines to international settings, particularly to low- and middle-income - countries. -CI - Copyright © 2012 Elsevier B.V. All rights reserved. -FAU - Stranges, S -AU - Stranges S -AD - Division of Health Sciences, University of Warwick Medical School, Medical School - Building, Gibbet Hill Campus, Coventry CV4 7AL, United Kingdom. - S.Stranges@warwick.ac.uk -FAU - Guallar, E -AU - Guallar E -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121102 -PL - Netherlands -TA - Nutr Metab Cardiovasc Dis -JT - Nutrition, metabolism, and cardiovascular diseases : NMCD -JID - 9111474 -SB - IM -MH - Cardiovascular Diseases/*epidemiology/*prevention & control -MH - Female -MH - Humans -MH - Life Style -MH - Practice Guidelines as Topic -MH - Randomized Controlled Trials as Topic -MH - Risk Factors -MH - United States/epidemiology -EDAT- 2012/11/06 06:00 -MHDA- 2013/05/15 06:00 -CRDT- 2012/11/06 06:00 -PHST- 2012/07/17 00:00 [received] -PHST- 2012/09/27 00:00 [revised] -PHST- 2012/10/04 00:00 [accepted] -PHST- 2012/11/06 06:00 [entrez] -PHST- 2012/11/06 06:00 [pubmed] -PHST- 2013/05/15 06:00 [medline] -AID - S0939-4753(12)00223-2 [pii] -AID - 10.1016/j.numecd.2012.10.001 [doi] -PST - ppublish -SO - Nutr Metab Cardiovasc Dis. 2012 Dec;22(12):1013-8. doi: - 10.1016/j.numecd.2012.10.001. Epub 2012 Nov 2. - -PMID- 21466619 -OWN - NLM -STAT- MEDLINE -DCOM- 20110818 -LR - 20250529 -IS - 1751-7176 (Electronic) -IS - 1524-6175 (Print) -IS - 1524-6175 (Linking) -VI - 13 -IP - 4 -DP - 2011 Apr -TI - Comorbidities of diabetes and hypertension: mechanisms and approach to target - organ protection. -PG - 244-51 -LID - 10.1111/j.1751-7176.2011.00434.x [doi] -AB - Up to 75% of adults with diabetes also have hypertension, and patients with - hypertension alone often show evidence of insulin resistance. Thus, hypertension - and diabetes are common, intertwined conditions that share a significant overlap - in underlying risk factors (including ethnicity, familial, dyslipidemia, and - lifestyle determinants) and complications. These complications include - microvascular and macrovascular disorders. The macrovascular complications, which - are well recognized in patients with longstanding diabetes or hypertension, - include coronary artery disease, myocardial infarction, stroke, congestive heart - failure, and peripheral vascular disease. Although microvascular complications - (retinopathy, nephropathy, and neuropathy) are conventionally linked to - hyperglycemia, studies have shown that hypertension constitutes an important risk - factor, especially for nephropathy. The familial predisposition to diabetes and - hypertension appears to be polygenic in origin, which militates against the - feasibility of a "gene therapy" approach to the control or prevention of these - conditions. On the other hand, the shared lifestyle factors in the etiology of - hypertension and diabetes provide ample opportunity for nonpharmacologic - intervention. Thus, the initial approach to the management of both diabetes and - hypertension must emphasize weight control, physical activity, and dietary - modification. Interestingly, lifestyle intervention is remarkably effective in - the primary prevention of diabetes and hypertension. These principles also are - pertinent to the prevention of downstream macrovascular complications of the two - disorders. In addition to lifestyle modification, most patients will require - specific medications to achieve national treatment goals for hypertension and - diabetes. Management of hyperglycemia, hypertension, dyslipidemia, and the - underlying hypercoagulable and proinflammatory states requires the use of - multiple medications in combination. -CI - © 2011 Wiley Periodicals, Inc. -FAU - Long, Amanda N -AU - Long AN -AD - Division of Endocrinology, Diabetes and Metabolism, University of Tennessee - College of Medicine, Memphis, TN 38163, USA. -FAU - Dagogo-Jack, Samuel -AU - Dagogo-Jack S -LA - eng -GR - M01 RR000211/RR/NCRR NIH HHS/United States -GR - R01 DK067269/DK/NIDDK NIH HHS/United States -GR - MO1 RR00211/RR/NCRR NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - J Clin Hypertens (Greenwich) -JT - Journal of clinical hypertension (Greenwich, Conn.) -JID - 100888554 -SB - IM -MH - Adult -MH - Comorbidity -MH - Diabetes Complications/*epidemiology/prevention & control -MH - Humans -MH - Hypertension/*epidemiology/prevention & control -PMC - PMC3746062 -MID - NIHMS266892 -EDAT- 2011/04/07 06:00 -MHDA- 2011/08/19 06:00 -PMCR- 2011/04/05 -CRDT- 2011/04/07 06:00 -PHST- 2011/04/07 06:00 [entrez] -PHST- 2011/04/07 06:00 [pubmed] -PHST- 2011/08/19 06:00 [medline] -PHST- 2011/04/05 00:00 [pmc-release] -AID - JCH434 [pii] -AID - 10.1111/j.1751-7176.2011.00434.x [doi] -PST - ppublish -SO - J Clin Hypertens (Greenwich). 2011 Apr;13(4):244-51. doi: - 10.1111/j.1751-7176.2011.00434.x. - -PMID- 18774012 -OWN - NLM -STAT- MEDLINE -DCOM- 20080925 -LR - 20151119 -IS - 1873-1740 (Electronic) -IS - 0033-0620 (Linking) -VI - 51 -IP - 2 -DP - 2008 Sep-Oct -TI - Cardiac magnetic resonance for risk stratification: the sudden death risk - portrayed. -PG - 128-34 -LID - 10.1016/j.pcad.2007.12.002 [doi] -AB - Risk stratification of patients with structural heart disease remains - problematic. While patients with low ejection fractions have been shown to be at - significant risk for sudden cardiac death, a risk that can be decreased by ICD - implantation, the sensitivity and specificity of ejection fraction for predicting - sudden death are sub-optimal. Contrast enhanced magnetic resonance imaging (CMRI) - has been shown to carefully delineate the extent and morphology of myocardial - scar. Recent studies have suggested that the extent of myocardial scar and - potentially its heterogeneity can help risk stratify patient with coronary artery - disease. Ongoing clinical studies will help determine the utility of - incorporating CMRI into a risk prediction algorithm. -FAU - Villuendas, Roger -AU - Villuendas R -AD - Division of Cardiology and Department of Medicine, Northwestern - University-Feinberg School of Medicine, Chicago, IL 60611, USA. -FAU - Kadish, Alan H -AU - Kadish AH -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Prog Cardiovasc Dis -JT - Progress in cardiovascular diseases -JID - 0376442 -RN - 0 (Contrast Media) -RN - AU0V1LM3JT (Gadolinium) -SB - IM -MH - Arrhythmias, Cardiac/complications/etiology/*pathology/therapy -MH - Cardiomyopathies/complications/etiology/*pathology/therapy -MH - Cardiomyopathy, Dilated/complications/etiology/*pathology/therapy -MH - Contrast Media -MH - Death, Sudden, Cardiac/*etiology/pathology/prevention & control -MH - Defibrillators, Implantable -MH - Electric Countershock/adverse effects/instrumentation -MH - Gadolinium -MH - Humans -MH - Image Enhancement -MH - Image Interpretation, Computer-Assisted -MH - *Magnetic Resonance Imaging -MH - Myocardial Ischemia/complications/*pathology/therapy -MH - Patient Selection -MH - Predictive Value of Tests -MH - Risk Assessment -MH - Risk Factors -RF - 38 -EDAT- 2008/09/09 09:00 -MHDA- 2008/09/26 09:00 -CRDT- 2008/09/09 09:00 -PHST- 2008/09/09 09:00 [pubmed] -PHST- 2008/09/26 09:00 [medline] -PHST- 2008/09/09 09:00 [entrez] -AID - S0033-0620(07)00124-7 [pii] -AID - 10.1016/j.pcad.2007.12.002 [doi] -PST - ppublish -SO - Prog Cardiovasc Dis. 2008 Sep-Oct;51(2):128-34. doi: 10.1016/j.pcad.2007.12.002. - -PMID- 20857618 -OWN - NLM -STAT- MEDLINE -DCOM- 20101005 -LR - 20191111 -IS - 0065-2423 (Print) -IS - 0065-2423 (Linking) -VI - 51 -DP - 2010 -TI - Cocaine in acute myocardial infarction. -PG - 53-70 -AB - Cocaine, a crystalline tropane alkaloid which is obtained from the leaves of the - coca plant, acts a powerfully addictive stimulant that directly targets the - central nervous system. The effects of the drug appear almost immediately after a - single dose (intravenous, intranasal, or inhaled), and disappear within a few - minutes or hours. Although the free commercialization of the drug is illicit and - severely penalized in virtually all countries, its use remains widespread in many - social, cultural, and personal settings. There is a variety of well-recognized - side effects of cocaine abuse, which involve virtually every organ system. There - is also emerging evidence, however, that cocaine abuse might trigger a variety of - cardiac disorders, ranging from arrhythmias to acute myocardial infarction (AMI), - heart failure and even sudden cardiac death, especially in relatively young male - patients (e.g., those in the mid-1930s), in those who concomitantly use tobacco - and alcohol, in those having experienced a trauma or a car accident and lack - traditional risk factors for atherosclerosis. Since the use of cocaine may - influence the treatment strategies of patients being evaluated for possible acute - coronary syndrome (ACS) as well as the prognosis of an AMI, it might be advisable - to introduce cocaine screening in patients admitted with chest pain at the - emergence department, especially in high-risk patients (i.e., young males with - concurrent use of tobacco or alcohol, suffering from a recent accident and with - no traditional atherosclerotic risk factors), or in those who are unresponsive - and unreliable. This strategy might be helpful to adopt the best therapeutic - approach for reducing the risks associated with cardiovascular disease in these - patients, and also to deter relapse. -FAU - Lippi, Giuseppe -AU - Lippi G -AD - U.O. Diagnostica Ematochimica, Dipartimento di Patologiae Medicina di - Laboratorio, Azienda Ospedaliero-Universitaria di Parma, Italy. glippi@ao.pr.it -FAU - Plebani, Mario -AU - Plebani M -FAU - Cervellin, Gianfranco -AU - Cervellin G -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Adv Clin Chem -JT - Advances in clinical chemistry -JID - 2985173R -RN - I5Y540LHVR (Cocaine) -SB - IM -MH - Acute Disease -MH - Animals -MH - Chest Pain/chemically induced -MH - Cocaine/analysis/chemistry/metabolism/*toxicity -MH - Cocaine-Related Disorders/complications/epidemiology -MH - Female -MH - Humans -MH - Male -MH - Myocardial Infarction/*chemically induced -EDAT- 2010/09/23 06:00 -MHDA- 2010/10/06 06:00 -CRDT- 2010/09/23 06:00 -PHST- 2010/09/23 06:00 [entrez] -PHST- 2010/09/23 06:00 [pubmed] -PHST- 2010/10/06 06:00 [medline] -AID - 10.1016/s0065-2423(10)51003-5 [doi] -PST - ppublish -SO - Adv Clin Chem. 2010;51:53-70. doi: 10.1016/s0065-2423(10)51003-5. - -PMID- 23903347 -OWN - NLM -STAT- MEDLINE -DCOM- 20140710 -LR - 20250529 -IS - 1432-2099 (Electronic) -IS - 0301-634X (Print) -IS - 0301-634X (Linking) -VI - 52 -IP - 4 -DP - 2013 Nov -TI - A review of non-cancer effects, especially circulatory and ocular diseases. -PG - 435-49 -LID - 10.1007/s00411-013-0484-7 [doi] -AB - There is a well-established association between high doses (>5 Gy) of ionizing - radiation exposure and damage to the heart and coronary arteries, although only - recently have studies with high-quality individual dosimetry been conducted that - would enable quantification of this risk adjusting for concomitant chemotherapy. - The association between lower dose exposures and late occurring circulatory - disease has only recently begun to emerge in the Japanese atomic bomb survivors - and in various occupationally exposed cohorts and is still controversial. Excess - relative risks per unit dose in moderate- and low-dose epidemiological studies - are somewhat variable, possibly a result of confounding and effect modification - by well-known (but unobserved) risk factors. Radiation doses of 1 Gy or more are - associated with increased risk of posterior subcapsular cataract. Accumulating - evidence from the Japanese atomic bomb survivors, Chernobyl liquidators, US - astronauts, and various other exposed groups suggests that cortical cataracts may - also be associated with ionizing radiation, although there is little evidence - that nuclear cataracts are radiogenic. The dose-response appears to be linear, - although modest thresholds (of no more than about 0.6 Gy) cannot be ruled out. A - variety of other non-malignant effects have been observed after moderate/low-dose - exposure in various groups, in particular respiratory and digestive disease and - central nervous system (and in particular neuro-cognitive) damage. However, - because these are generally only observed in isolated groups, or because the - evidence is excessively heterogeneous, these associations must be treated with - caution. -FAU - Little, Mark P -AU - Little MP -AD - Radiation Epidemiology Branch, National Cancer Institute, 9609 Medical Center - Drive MSC 9778, Bethesda, MD, 20892-9778, USA, mark.little@nih.gov. -LA - eng -GR - ZIA CP010132/ImNIH/Intramural NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Intramural -PT - Review -DEP - 20130801 -PL - Germany -TA - Radiat Environ Biophys -JT - Radiation and environmental biophysics -JID - 0415677 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/epidemiology/*etiology -MH - Endpoint Determination -MH - Eye Diseases/epidemiology/*etiology -MH - Humans -MH - Nuclear Weapons -MH - Occupational Exposure/adverse effects -MH - *Radiation Injuries/epidemiology/etiology -PMC - PMC4074546 -MID - NIHMS546677 -EDAT- 2013/08/02 06:00 -MHDA- 2014/07/11 06:00 -PMCR- 2014/06/29 -CRDT- 2013/08/02 06:00 -PHST- 2013/03/02 00:00 [received] -PHST- 2013/07/14 00:00 [accepted] -PHST- 2013/08/02 06:00 [entrez] -PHST- 2013/08/02 06:00 [pubmed] -PHST- 2014/07/11 06:00 [medline] -PHST- 2014/06/29 00:00 [pmc-release] -AID - 10.1007/s00411-013-0484-7 [doi] -PST - ppublish -SO - Radiat Environ Biophys. 2013 Nov;52(4):435-49. doi: 10.1007/s00411-013-0484-7. - Epub 2013 Aug 1. - -PMID- 21452060 -OWN - NLM -STAT- MEDLINE -DCOM- 20111114 -LR - 20250529 -IS - 1937-5395 (Electronic) -IS - 1937-5387 (Print) -IS - 1937-5387 (Linking) -VI - 4 -IP - 4 -DP - 2011 Aug -TI - Emerging MRI methods in translational cardiovascular research. -PG - 477-92 -LID - 10.1007/s12265-011-9275-1 [doi] -AB - Cardiac magnetic resonance imaging (CMR) has become a reference standard modality - for imaging of left ventricular (LV) structure and function and, using late - gadolinium enhancement, for imaging myocardial infarction. Emerging CMR - techniques enable a more comprehensive examination of the heart, making CMR an - excellent tool for use in translational cardiovascular research. Specifically, - emerging CMR methods have been developed to measure the extent of myocardial - edema, changes in ventricular mechanics, changes in tissue composition as a - result of fibrosis, and changes in myocardial perfusion as a function of both - disease and infarct healing. New CMR techniques also enable the tracking of - labeled cells, molecular imaging of biomarkers of disease, and changes in calcium - flux in cardiomyocytes. In addition, MRI can quantify blood flow velocity and - wall shear stress in large blood vessels. Almost all of these techniques can be - applied in both pre-clinical and clinical settings, enabling both the techniques - themselves and the knowledge gained using such techniques in pre-clinical - research to be translated from the lab bench to the patient bedside. -FAU - Vandsburger, Moriel H -AU - Vandsburger MH -AD - Department of Biological Regulation, Weizmann Institute of Science, 76100, - Rehovot, Israel. moriel.vandsburger@gmail.com -FAU - Epstein, Frederick H -AU - Epstein FH -LA - eng -GR - R01 EB001763/EB/NIBIB NIH HHS/United States -GR - R01 EB 001763/EB/NIBIB NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20110331 -PL - United States -TA - J Cardiovasc Transl Res -JT - Journal of cardiovascular translational research -JID - 101468585 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*diagnosis/metabolism/pathology/physiopathology -MH - Coronary Circulation -MH - Fibrosis -MH - Humans -MH - *Magnetic Resonance Imaging -MH - Molecular Imaging/*methods -MH - *Myocardial Perfusion Imaging -MH - Myocardium/metabolism/pathology -MH - Predictive Value of Tests -MH - Severity of Illness Index -MH - *Translational Research, Biomedical -MH - Ventricular Function, Left -PMC - PMC3134552 -MID - NIHMS302857 -EDAT- 2011/04/01 06:00 -MHDA- 2011/11/15 06:00 -PMCR- 2012/08/01 -CRDT- 2011/04/01 06:00 -PHST- 2011/02/23 00:00 [received] -PHST- 2011/03/15 00:00 [accepted] -PHST- 2011/04/01 06:00 [entrez] -PHST- 2011/04/01 06:00 [pubmed] -PHST- 2011/11/15 06:00 [medline] -PHST- 2012/08/01 00:00 [pmc-release] -AID - 10.1007/s12265-011-9275-1 [doi] -PST - ppublish -SO - J Cardiovasc Transl Res. 2011 Aug;4(4):477-92. doi: 10.1007/s12265-011-9275-1. - Epub 2011 Mar 31. - -PMID- 19601865 -OWN - NLM -STAT- MEDLINE -DCOM- 20090826 -LR - 20220331 -IS - 1570-1611 (Print) -IS - 1570-1611 (Linking) -VI - 7 -IP - 3 -DP - 2009 Jul -TI - Vitamin D and cardiovascular disease. -PG - 414-22 -AB - Cardiovascular disease (CVD) is a major cause of morbidity and mortality - worldwide. Recently vitamin D deficiency has been identified as a potential risk - factor for many diseases not traditionally associated with vitamin D, such as - cancer and CVD. This review discusses the evidence suggesting an association - between low 25-hydroxyvitamin D levels and CVD and the possible mechanisms - mediating it. Vitamin D deficiency has been associated with CVD risk factors such - as hypertension and diabetes mellitus, with markers of subclinical - atherosclerosis such as intima-media thickness and coronary calcification as well - as with cardiovascular events such as myocardial infarction and stroke as well as - congestive heart failure. It could be suggested that vitamin D deficiency - contributes to the development of CVD through its association with risk factors, - such as diabetes and hypertension. However, direct effects of vitamin D on the - cardiovascular system may also be involved. Vitamin D receptors are expressed in - a variety of tissues, including cardiomyocytes, vascular smooth muscle cells and - endothelial cells and vitamin D has been shown to affect inflammation and cell - proliferation and differentiation. While much evidence supports a potential - antiatherosclerotic effect of vitamin D, prospective, placebo-controlled - randomized as well as mechanistic studies are needed to confirm this association. - Since vitamin D deficiency is easy to screen for and treat, the confirmation of - such an association could have important implications for both, patient care and - health policy. -FAU - Gouni-Berthold, Ioanna -AU - Gouni-Berthold I -AD - Department of Internal Medicine II, University of Cologne, D-50937 Cologne, - Germany. ioanna.berthold@uni-koeln.de -FAU - Krone, Wilhelm -AU - Krone W -FAU - Berthold, Heiner K -AU - Berthold HK -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Vasc Pharmacol -JT - Current vascular pharmacology -JID - 101157208 -RN - 0 (Receptors, Calcitriol) -RN - 0 (Vitamin D-Binding Protein) -RN - 1406-16-2 (Vitamin D) -SB - IM -MH - Atherosclerosis/complications/genetics -MH - Cardiovascular Diseases/diagnosis/*metabolism -MH - Clinical Trials as Topic -MH - Cohort Studies -MH - Diabetes Complications/metabolism -MH - Humans -MH - Inflammation/complications/metabolism -MH - Polymorphism, Genetic -MH - Receptors, Calcitriol/genetics/physiology -MH - Risk Factors -MH - Vitamin D/*metabolism/physiology/*therapeutic use -MH - Vitamin D Deficiency/complications -MH - Vitamin D-Binding Protein/physiology -RF - 115 -EDAT- 2009/07/16 09:00 -MHDA- 2009/08/27 09:00 -CRDT- 2009/07/16 09:00 -PHST- 2009/07/16 09:00 [entrez] -PHST- 2009/07/16 09:00 [pubmed] -PHST- 2009/08/27 09:00 [medline] -AID - 10.2174/157016109788340686 [doi] -PST - ppublish -SO - Curr Vasc Pharmacol. 2009 Jul;7(3):414-22. doi: 10.2174/157016109788340686. - -PMID- 19545988 -OWN - NLM -STAT- MEDLINE -DCOM- 20091123 -LR - 20131121 -IS - 1532-2823 (Electronic) -IS - 0952-3278 (Linking) -VI - 81 -IP - 2-3 -DP - 2009 Aug-Sep -TI - Docosahexaenoic acid (DHA) and cardiovascular disease risk factors. -PG - 199-204 -LID - 10.1016/j.plefa.2009.05.016 [doi] -AB - Numerous epidemiological and controlled interventional trials have supported the - health benefits of long-chain omega-3 fatty acids in the form of docosahexaenoic - acid (DHA, 22:6n-3) plus eicosapentaenoic acid (EPA, 20:5n-3) from fish and fish - oils as well as from algal sources. The beneficial effects on cardiovascular - disease and related mortality including various risk factors for cardiovascular - disease (particularly lowering circulating triglyceride levels and the - triglyceride:HDL-cholesterol ratio) have been observed in the absence of any - concomitant blood cholesterol lowering. With appropriate dosages, consistent - reductions in both fasting and postprandial triglyceride levels and moderate - increases in fasting HDL-cholesterol levels have been observed with algal DHA in - the majority of trials. These results are similar to findings for fish oils - containing DHA and EPA. Related to greater fish intake, higher levels of DHA in - circulating blood biomarkers (such as serum phospholipid) have been associated - with reduced risks for the progression of coronary atherosclerosis and lowered - risk from sudden cardiac death. Controlled clinical trials have also indicated - the potential for algal DHA supplementation to have moderate beneficial effects - on other cardiovascular disease risk factors including blood pressures and - resting heart rates. Recommended intakes of DHA+EPA from numerous international - groups for the prevention and management of cardiovascular disease have been - forthcoming, although most have not offered specific recommendations for the - optimal individual intake of DHA and EPA. -FAU - Holub, Bruce J -AU - Holub BJ -AD - Department of Human Health and Nutritional Sciences, University of Guelph, - Guelph, Ontario, Canada N1G2W1. bholub@uoguelph.ca -LA - eng -PT - Journal Article -PT - Review -DEP - 20090709 -PL - Scotland -TA - Prostaglandins Leukot Essent Fatty Acids -JT - Prostaglandins, leukotrienes, and essential fatty acids -JID - 8802730 -RN - 0 (Cholesterol, HDL) -RN - 0 (Fatty Acids, Omega-3) -RN - 0 (Fish Oils) -RN - 0 (Triglycerides) -RN - 25167-62-8 (Docosahexaenoic Acids) -RN - AAN7QOV9EA (Eicosapentaenoic Acid) -SB - IM -MH - Cardiovascular Diseases/blood/drug therapy/*prevention & control -MH - Cholesterol, HDL/blood -MH - Dietary Supplements -MH - *Docosahexaenoic Acids/administration & dosage/blood/therapeutic use -MH - Eicosapentaenoic Acid/administration & dosage/therapeutic use -MH - Eukaryota -MH - Fatty Acids, Omega-3/administration & dosage -MH - Fish Oils/administration & dosage -MH - Humans -MH - Nutrition Policy -MH - Risk Factors -MH - Triglycerides/blood -RF - 50 -EDAT- 2009/06/24 09:00 -MHDA- 2009/12/16 06:00 -CRDT- 2009/06/24 09:00 -PHST- 2009/06/24 09:00 [entrez] -PHST- 2009/06/24 09:00 [pubmed] -PHST- 2009/12/16 06:00 [medline] -AID - S0952-3278(09)00091-X [pii] -AID - 10.1016/j.plefa.2009.05.016 [doi] -PST - ppublish -SO - Prostaglandins Leukot Essent Fatty Acids. 2009 Aug-Sep;81(2-3):199-204. doi: - 10.1016/j.plefa.2009.05.016. Epub 2009 Jul 9. - -PMID- 17374084 -OWN - NLM -STAT- MEDLINE -DCOM- 20070810 -LR - 20231213 -IS - 0894-0959 (Print) -IS - 0894-0959 (Linking) -VI - 20 -IP - 2 -DP - 2007 Mar-Apr -TI - Inhibitors of calcification in blood and urine. -PG - 113-21 -AB - In bone and teeth formation, coordinated calcification is a highly desirable - biological process. However, heterotopic calcification at unwanted tissue sites - leads to dysfunction, disease and, potentially, to death and therefore requires - prevention and treatment. With the recent discovery of calcification inhibitors - we now know that biological calcification is not passive but a complex, active - and highly regulated process. Calcification at vascular sites is the most - threatening localization and manifests as part of atherosclerosis or - arteriosclerosis. Atherosclerosis is often accompanied by intimal plaque - calcification, whereas arteriosclerosis is characterized by calcification of the - media. The severity of calcification of cerebral or coronary atherosclerotic - plaques is associated with an increased incidence of events such as stroke or - myocardial infarction. Medial calcification is the major cause of arterial - stiffness, which contributes to left ventricular dysfunction and heart failure. - Patients with chronic kidney disease are at especially increased risk for both - intimal and medial calcification. In this context, it is currently thought that - calcium-regulatory factors including fetuin-A, matrix Gla protein, - osteoprotegerin, and pyrophosphates act in a local or systemic manner to prevent - calcifications of the vasculature, and that dys-regulations of such calcification - inhibitors may contribute to progressive calcifications. Nephrolithiasis - represents another process of unwanted calcification responsible for significant - morbidity. More than 80% of renal stones contain calcium. Urinary factors - inhibiting calcification are citrate, glycosaminoglycans, Tamm-Horsfall protein, - and osteopontin. This review summarizes current experimental and clinical data - underlining the biological importance of these calcification inhibitors. -FAU - Schlieper, Georg -AU - Schlieper G -AD - Department of Nephrology and Clinical Immunology, University Hospital Aachen, - Aachen, Germany. gschlieper@ukaachen.de -FAU - Westenfeld, Ralf -AU - Westenfeld R -FAU - Brandenburg, Vincent -AU - Brandenburg V -FAU - Ketteler, Markus -AU - Ketteler M -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Semin Dial -JT - Seminars in dialysis -JID - 8911629 -RN - 0 (AHSG protein, human) -RN - 0 (Biomarkers) -RN - 0 (Blood Proteins) -RN - 0 (Calcium-Binding Proteins) -RN - 0 (Diphosphates) -RN - 0 (Extracellular Matrix Proteins) -RN - 0 (Glycosaminoglycans) -RN - 0 (Mucoproteins) -RN - 0 (Osteoprotegerin) -RN - 0 (UMOD protein, human) -RN - 0 (Uromodulin) -RN - 0 (alpha-2-HS-Glycoprotein) -RN - 106441-73-0 (Osteopontin) -RN - 2968PHW8QP (Citric Acid) -SB - IM -MH - Animals -MH - Biomarkers/blood/urine -MH - Blood Proteins/metabolism -MH - Calcinosis/*blood/*urine -MH - Calcium-Binding Proteins/blood -MH - Cardiovascular Diseases/*blood/*urine -MH - Citric Acid/urine -MH - Diphosphates/blood -MH - Extracellular Matrix Proteins/blood -MH - Glycosaminoglycans/urine -MH - Humans -MH - Mucoproteins/urine -MH - Osteopontin/urine -MH - Osteoprotegerin/blood -MH - Uremia/blood/urine -MH - Uromodulin -MH - alpha-2-HS-Glycoprotein -MH - Matrix Gla Protein -RF - 127 -EDAT- 2007/03/22 09:00 -MHDA- 2007/08/11 09:00 -CRDT- 2007/03/22 09:00 -PHST- 2007/03/22 09:00 [pubmed] -PHST- 2007/08/11 09:00 [medline] -PHST- 2007/03/22 09:00 [entrez] -AID - SDI257 [pii] -AID - 10.1111/j.1525-139X.2007.00257.x [doi] -PST - ppublish -SO - Semin Dial. 2007 Mar-Apr;20(2):113-21. doi: 10.1111/j.1525-139X.2007.00257.x. - -PMID- 20470213 -OWN - NLM -STAT- MEDLINE -DCOM- 20101124 -LR - 20151119 -IS - 1502-7686 (Electronic) -IS - 0036-5513 (Linking) -VI - 70 -IP - 5 -DP - 2010 Sep -TI - Biomarkers of alcohol consumption and related liver disease. -PG - 305-12 -LID - 10.3109/00365513.2010.486442 [doi] -AB - Abstract Alcohol abuse is a major cause of abnormal liver function throughout the - world. While measurements of liver enzyme activities (GGT, ALT, AST) are - important screening tools for detecting liver disease, due to lack of - ethanol-specificity and inconsistencies regarding the definitions of significant - alcohol consumption, several other blood tests are usually needed to exclude - competing and co-existing causes of abnormal liver function. Information on the - specific role of ethanol consumption behind hepatotoxicity may be obtained - through measurements of blood ethanol and its specific metabolites (ethyl - glucuronide, phosphatidylethanol, protein-acetaldehyde condensates and associated - autoimmune responses). Recent studies have indicated that being overweight is - another increasingly common cause of abnormal liver enzyme levels and adiposity - may also increase the impact of ethanol consumption on liver pathology. - Interestingly, increased liver enzyme activities in circulation may reflect not - only hepatic function but can also serve as indicators of general health and the - status of oxidative stress in vivo. ALT and GGT activities predict insulin - resistance, metabolic syndrome, mortality from coronary heart diseases and even - mortality from all causes. If the upper reference limits for liver enzyme - activities were defined based on the data obtained from normal weight abstainers, - the clinical value of liver enzyme measurements as screening tools and in patient - follow-up could be significantly improved. -FAU - Niemelä, Onni -AU - Niemelä O -AD - Department of Laboratory Medicine and Medical Research Unit, Seinäjoki Central - Hospital and University of Tampere, Seinäjoki, Finland. onni.niemela@epshp.fi -FAU - Alatalo, Päivikki -AU - Alatalo P -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Scand J Clin Lab Invest -JT - Scandinavian journal of clinical and laboratory investigation -JID - 0404375 -RN - 0 (Biomarkers) -RN - 0 (Transferrin) -RN - 0 (carbohydrate-deficient transferrin) -RN - EC 2.3.2.2 (gamma-Glutamyltransferase) -RN - EC 2.6.1.1 (Aspartate Aminotransferases) -RN - EC 2.6.1.2 (Alanine Transaminase) -SB - IM -MH - Alanine Transaminase/blood -MH - Alcohol Drinking/*blood -MH - Alcoholism/*blood -MH - Aspartate Aminotransferases/blood -MH - Biomarkers/*blood -MH - Body Mass Index -MH - Erythrocytes/drug effects -MH - Humans -MH - Liver/enzymology -MH - Liver Cirrhosis/etiology -MH - Liver Diseases/*enzymology -MH - Obesity/complications/enzymology -MH - Transferrin/analogs & derivatives/analysis -MH - gamma-Glutamyltransferase/blood -EDAT- 2010/05/18 06:00 -MHDA- 2010/12/14 06:00 -CRDT- 2010/05/18 06:00 -PHST- 2010/05/18 06:00 [entrez] -PHST- 2010/05/18 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -AID - 10.3109/00365513.2010.486442 [doi] -PST - ppublish -SO - Scand J Clin Lab Invest. 2010 Sep;70(5):305-12. doi: - 10.3109/00365513.2010.486442. - -PMID- 23276595 -OWN - NLM -STAT- MEDLINE -DCOM- 20130910 -LR - 20220310 -IS - 1532-8422 (Electronic) -IS - 1053-0770 (Linking) -VI - 27 -IP - 2 -DP - 2013 Apr -TI - β-blockers and volatile anesthetics may attenuate cardioprotection by remote - preconditioning in adult cardiac surgery: a meta-analysis of 15 randomized - trials. -PG - 305-11 -LID - S1053-0770(12)00530-7 [pii] -LID - 10.1053/j.jvca.2012.09.028 [doi] -AB - OBJECTIVE: Clinical trials on cardioprotection by remote ischemic preconditioning - (RIPC) for adult patients undergoing cardiac surgery revealed mixed results. - Previous meta-analyses have been conducted and found marked heterogeneity among - studies. The aim of this meta-analysis was to evaluate the factors affecting - cardioprotection by remote preconditioning in adult cardiac surgery. DESIGN: A - meta-analysis of randomized controlled trials. SETTING: University hospitals. - PARTICIPANTS: Adult subjects undergoing cardiac surgery. INTERVENTIONS: RIPC. - MEASUREMENTS AND MAIN RESULTS: Fifteen trials with a total of 1,155 study - patients reporting postoperative myocardial biomarker (CK-MB or troponin) levels - were identified from PubMed, Embase, and the Cochrane Library (up to July 2012). - Compared with controls, RIPC significantly reduced postoperative biomarkers of - myocardial injury (standardized mean difference = -0.31, p = 0.041; heterogeneity - test: I(2) = 83.5%). This effect seemed more significant in valve surgery - (standardized mean difference = -0.74, p = 0.002) than in coronary artery surgery - (standardized mean difference = -0.23; p = 0.17). Univariate meta-regression - analyses suggested that the major sources of significant heterogeneity were - β-blockers (%) (coefficient = 0.0161, p = 0.022, adjusted R(2) = 0.37) and - volatile anesthetics (coefficient = 0.6617, p = 0.065, adjusted R(2) = 0.22). - These results were further confirmed in multivariate regression and subgroup - analyses. CONCLUSIONS: Available data from this meta-analysis further confirmed - the cardioprotection conferred by RIPC in adult cardiac surgery. Moreover, the - cardioprotective effect may be attenuated when combined with β-blockers or - volatile anesthetics. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Zhou, Chenghui -AU - Zhou C -AD - State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center - for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union - Medical College, Beijing, China. -FAU - Liu, Yang -AU - Liu Y -FAU - Yao, Yuntai -AU - Yao Y -FAU - Zhou, Shan -AU - Zhou S -FAU - Fang, Nengxin -AU - Fang N -FAU - Wang, Weipeng -AU - Wang W -FAU - Li, Lihuan -AU - Li L -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121229 -PL - United States -TA - J Cardiothorac Vasc Anesth -JT - Journal of cardiothoracic and vascular anesthesia -JID - 9110208 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Anesthetics, Inhalation) -RN - 0 (Biomarkers) -RN - 0 (Cardiotonic Agents) -RN - 0 (Troponin) -RN - EC 2.7.3.2 (Creatine Kinase, MB Form) -SB - IM -MH - Adrenergic beta-Antagonists/*therapeutic use -MH - Adult -MH - Anesthetics, Inhalation/*therapeutic use -MH - Angioplasty, Balloon, Coronary -MH - Biomarkers/analysis -MH - Cardiac Surgical Procedures/*methods/mortality -MH - *Cardiotonic Agents -MH - Child -MH - Confidence Intervals -MH - Coronary Artery Bypass -MH - Creatine Kinase, MB Form/blood -MH - Data Interpretation, Statistical -MH - Endpoint Determination -MH - Heart Valve Prosthesis Implantation -MH - Humans -MH - Ischemic Preconditioning, Myocardial/*methods -MH - Postoperative Period -MH - Randomized Controlled Trials as Topic -MH - Research Design -MH - Troponin/blood -EDAT- 2013/01/02 06:00 -MHDA- 2013/09/11 06:00 -CRDT- 2013/01/02 06:00 -PHST- 2012/07/15 00:00 [received] -PHST- 2013/01/02 06:00 [entrez] -PHST- 2013/01/02 06:00 [pubmed] -PHST- 2013/09/11 06:00 [medline] -AID - S1053-0770(12)00530-7 [pii] -AID - 10.1053/j.jvca.2012.09.028 [doi] -PST - ppublish -SO - J Cardiothorac Vasc Anesth. 2013 Apr;27(2):305-11. doi: - 10.1053/j.jvca.2012.09.028. Epub 2012 Dec 29. - -PMID- 22338574 -OWN - NLM -STAT- MEDLINE -DCOM- 20130107 -LR - 20191027 -IS - 1875-6212 (Electronic) -IS - 1570-1611 (Linking) -VI - 10 -IP - 5 -DP - 2012 Sep -TI - Platelets in atherothrombosis--diagnostic and prognostic value of platelet - activation in patients with atherosclerotic diseases. -PG - 589-96 -AB - Platelets and their activation have a pivotal role in the development of - atherosclerotic diseases such as acute myocardial infarction (AMI), stroke and - peripheral arterial occlusion. Biomarkers of platelet activation are making - inroads into clinical studies and may serve as promising agents upstream to - established downstream markers of myocardial necrosis such as troponin and - creatin kinase. Targeting the degree of platelet activation assessed by the key - collagen receptor of platelet activation, glycoprotein VI (GPVI), may have - diagnostic and prognostic value for the assessement of high-risk groups of - patients with symptomatic coronary artery disease and ischemic stroke and may be - worthwhile to help to facilitate clinical decision-making and to rapidly initiate - adequate therapy. The concert of platelet count, platelet activation, platelet - aggregation and subsequent inflammation has had a significant impact on the - clinical outcome in patients with atherosclerotic diseases. For a therapeutical - approach to ameliorate prognosis, the use of antiplatelet treatment in particular - in AMI patients with low response to clopidogrel has partly been overcome by - novel second antiplatelet drugs on top of aspirin such as prasugrel and - ticagrelor. Antiplatelet therapy may be adapted according to a GPVI-based - platelet activity monitoring along with aggregometry of residual platelet - aggregation. Other approaches using protease-activated receptor- 1 antagonists - vorapaxar or atopaxar, which inhibit the platelet thrombin receptor, soluble GPVI - called Revacept©, which blocks the collagen binding sites at the vascular lesion - and anopheline saliva protein derived from the malaria vector mosquito, a - platelet adhesion inhibitor independent of a GPVI mechanism, still wait for their - breakthrough. -FAU - Bigalke, Boris -AU - Bigalke B -AD - Medizinische Klinik III Kardiologie und Kreislauferkrankungen, Eberhard - Karls-Universität Tübingen, Otfried-Muller-Str. 10, 72070 Tübingen, Germany. - boris.bigalke@med.uni-tuebingen.de -FAU - Schuster, Andreas -AU - Schuster A -FAU - Sopova, Kateryna -AU - Sopova K -FAU - Wurster, Thomas -AU - Wurster T -FAU - Stellos, Konstantinos -AU - Stellos K -LA - eng -GR - FS/10/029/28253/British Heart Foundation/United Kingdom -GR - RE/08/003/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Vasc Pharmacol -JT - Current vascular pharmacology -JID - 101157208 -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Animals -MH - Arterial Occlusive Diseases/diagnosis/drug therapy/physiopathology -MH - Atherosclerosis/diagnosis/drug therapy/*physiopathology -MH - Blood Platelets/*metabolism -MH - Drug Therapy, Combination -MH - Humans -MH - Myocardial Infarction/diagnosis/drug therapy/physiopathology -MH - Peripheral Arterial Disease/diagnosis/drug therapy/physiopathology -MH - *Platelet Activation -MH - Platelet Aggregation Inhibitors/administration & dosage/therapeutic use -MH - Prognosis -MH - Stroke/diagnosis/drug therapy/physiopathology -MH - Thrombosis/diagnosis/drug therapy/physiopathology -EDAT- 2012/02/18 06:00 -MHDA- 2013/01/08 06:00 -CRDT- 2012/02/18 06:00 -PHST- 2011/06/24 00:00 [received] -PHST- 2011/10/13 00:00 [revised] -PHST- 2012/01/05 00:00 [accepted] -PHST- 2012/02/18 06:00 [entrez] -PHST- 2012/02/18 06:00 [pubmed] -PHST- 2013/01/08 06:00 [medline] -AID - CVP-EPUB-20120215-010 [pii] -AID - 10.2174/157016112801784468 [doi] -PST - ppublish -SO - Curr Vasc Pharmacol. 2012 Sep;10(5):589-96. doi: 10.2174/157016112801784468. - -PMID- 22116698 -OWN - NLM -STAT- MEDLINE -DCOM- 20140926 -LR - 20111125 -IS - 0306-0225 (Print) -IS - 0306-0225 (Linking) -VI - 56 -DP - 2012 -TI - Enzymatic and non-enzymatic antioxidative effects of folic acid and its reduced - derivates. -PG - 131-61 -LID - 10.1007/978-94-007-2199-9_8 [doi] -AB - A great part of the population appears to have insufficient folate intake, - especially subgroups with higher demand, as determined through more sensitive - methods and parameters currently in use. As the role of folate deficiency in - congenital defects, e.g. in cardiovascular and neurodegenerative diseases, and in - carcinogenesis has become better understood, folate has been recognized as having - great potential to prevent these many disorders through folate supplementation or - fortification for the general population. Folates are essential cofactors in the - transfer and utilization of one-carbon groups in the process of DNA-biosynthesis - with implications for genomic repair and stability. Folate acts indirectly to - lower homocysteine levels and insures optimal functioning of the methylation - cycle. Homocysteine was shown to be an independent risk factor for - neurodegenerative and cardiovascular disease, which includes peripheral vascular - disease, coronary artery disease, cerebrovascular disease and venous thrombosis. - In fact, it was long believed that the beneficial effects of folate on vascular - function and disease are related directly to the mechanism of - homocysteine-diminution. Recent investigations have, however, demonstrated - beneficial effects of folates unrelated to homocysteine-diminution, suggesting - independent properties. One such mechanism could be free radical scavenging and - antioxidant activity, as it is now recognized that free radicals play an - important role in the oxidative stress leading to many diseases. It was found - that folic acid and, in particular, its reduced derivates act both directly and - indirectly to produce antioxidant effects. Folates interact with the endothelial - enzyme NO synthase (eNOS) and, exert effects on the cofactor bioavailability of - NO and thus, on peroxynitrite formation. Folate metabolism provides an - interesting example of gene-environmental interaction. -FAU - Stanger, Olaf -AU - Stanger O -AD - Heart Division, Cardiothoracic Surgery, Royal Brompton and Harefield NHS - Foundation, Imperial College of Science, Technology and Medicine, Sydney Street, - London, SW3 6NP, UK, o.stanger@rbht.nhs.uk. -FAU - Wonisch, Willibald -AU - Wonisch W -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Subcell Biochem -JT - Sub-cellular biochemistry -JID - 0316571 -RN - 0 (Antioxidants) -RN - 0LVT1QZ0BA (Homocysteine) -RN - 935E97BOY8 (Folic Acid) -RN - EC 1.14.13.39 (Nitric Oxide Synthase Type III) -SB - IM -MH - Animals -MH - Antioxidants/*pharmacology -MH - Folic Acid/*analogs & derivatives/metabolism/*pharmacology -MH - Homocysteine/metabolism -MH - Homocystinuria/metabolism -MH - Humans -MH - Hyperhomocysteinemia/metabolism -MH - Lipid Peroxidation/drug effects -MH - Nitric Oxide Synthase Type III/physiology -MH - Oxidation-Reduction -MH - Oxidative Stress/*drug effects -EDAT- 2011/11/26 06:00 -MHDA- 2014/09/27 06:00 -CRDT- 2011/11/26 06:00 -PHST- 2011/11/26 06:00 [entrez] -PHST- 2011/11/26 06:00 [pubmed] -PHST- 2014/09/27 06:00 [medline] -AID - 10.1007/978-94-007-2199-9_8 [doi] -PST - ppublish -SO - Subcell Biochem. 2012;56:131-61. doi: 10.1007/978-94-007-2199-9_8. - -PMID- 20736082 -OWN - NLM -STAT- MEDLINE -DCOM- 20101210 -LR - 20161126 -IS - 0006-3002 (Print) -IS - 0006-3002 (Linking) -VI - 1801 -IP - 12 -DP - 2010 Dec -TI - The complexity of HDL. -PG - 1286-93 -LID - 10.1016/j.bbalip.2010.08.009 [doi] -AB - Plasma high-density lipoprotein cholesterol (HDL-C) levels are inversely - associated with coronary artery disease risk in large epidemiologic studies. This - rule, however, has many exceptions in individual patients, and evidence suggests - that other facets of high-density lipoprotein particle biology not captured by - measuring HDL-C levels are responsible for HDL's effects in vivo. This article - reviews the evidence for the protective nature of HDL, current evidence from - animal and human studies regarding HDL-based therapies, the major steps in HDL - particle formation and metabolism, alterations leading to dysfunctional HDL in - diabetes and inflammatory states, and potential alternatives to HDL-C to measure - HDL function and predict its protective value clinically. -CI - 2010 Elsevier B.V. All rights reserved. -FAU - Francis, Gordon A -AU - Francis GA -AD - Department of Medicine and UBC James Hogg Research Centre, Providence Heart and - Lung Institute, 1081 Burrard St., Vancouver, British Columbia, Canada. - gordon.fracis@hli.ubc.ca -LA - eng -GR - MOP-12660/Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100821 -PL - Netherlands -TA - Biochim Biophys Acta -JT - Biochimica et biophysica acta -JID - 0217513 -RN - 0 (Lipoproteins, HDL) -SB - IM -MH - Animals -MH - Humans -MH - Lipoproteins, HDL/*metabolism -EDAT- 2010/08/26 06:00 -MHDA- 2010/12/14 06:00 -CRDT- 2010/08/26 06:00 -PHST- 2010/06/25 00:00 [received] -PHST- 2010/08/16 00:00 [revised] -PHST- 2010/08/17 00:00 [accepted] -PHST- 2010/08/26 06:00 [entrez] -PHST- 2010/08/26 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -AID - S1388-1981(10)00187-3 [pii] -AID - 10.1016/j.bbalip.2010.08.009 [doi] -PST - ppublish -SO - Biochim Biophys Acta. 2010 Dec;1801(12):1286-93. doi: - 10.1016/j.bbalip.2010.08.009. Epub 2010 Aug 21. - -PMID- 23111860 -OWN - NLM -STAT- MEDLINE -DCOM- 20130627 -LR - 20220317 -IS - 1098-9064 (Electronic) -IS - 0094-6176 (Linking) -VI - 38 -IP - 8 -DP - 2012 Nov -TI - The adverse effects of estrogen and selective estrogen receptor modulators on - hemostasis and thrombosis. -PG - 797-807 -LID - 10.1055/s-0032-1328883 [doi] -AB - Agonists of the estrogen receptor include estrogens and selective estrogen - receptor modulators (SERMs). Both types of compounds increase the risk for - thrombosis in the arterial and the venous tree. The magnitude of the effect is - influenced by potency, which depends on the type of compound and the dose. The - particulars of the process change in each territory. Atherosclerosis, which - creates local inflammatory conditions, may favor thrombogenesis in arteries. A - direct effect of estrogen agonists is also well endorsed at both arteries, as - suggested from data with high-estrogenic contraceptives, and veins. Dose - reduction has been proved to be an effective strategy, but there is debate on - whether additional benefit may be attained beyond a certain threshold. Hormone - therapy and SERMs exhibit a lower potency estrogenic profile, but are mainly used - by older women, who have a baseline increased thrombogenic risk. When used as - sole agents, estrogens substantially reduce the increased risk (venous - thrombosis) or may even be neutral (coronary disease). SERMs exhibit a neutral - profile for coronary disease and possibly for stroke but not for venous - thrombosis. -CI - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA. -FAU - Artero, Arturo -AU - Artero A -AD - Service of Internal Medicine, University Hospital Dr Peset, Valencia, Spain. -FAU - Tarín, Juan J -AU - Tarín JJ -FAU - Cano, Antonio -AU - Cano A -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20121030 -PL - United States -TA - Semin Thromb Hemost -JT - Seminars in thrombosis and hemostasis -JID - 0431155 -RN - 0 (Estrogens) -RN - 0 (Selective Estrogen Receptor Modulators) -SB - IM -MH - Estrogens/*adverse effects/pharmacology -MH - Female -MH - Hemostasis/*drug effects -MH - Humans -MH - Selective Estrogen Receptor Modulators/*adverse effects/pharmacology -MH - Thrombosis/*chemically induced/drug therapy -EDAT- 2012/11/01 06:00 -MHDA- 2013/06/29 06:00 -CRDT- 2012/11/01 06:00 -PHST- 2012/11/01 06:00 [entrez] -PHST- 2012/11/01 06:00 [pubmed] -PHST- 2013/06/29 06:00 [medline] -AID - 10.1055/s-0032-1328883 [doi] -PST - ppublish -SO - Semin Thromb Hemost. 2012 Nov;38(8):797-807. doi: 10.1055/s-0032-1328883. Epub - 2012 Oct 30. - -PMID- 20167505 -OWN - NLM -STAT- MEDLINE -DCOM- 20101108 -LR - 20161125 -IS - 1532-8422 (Electronic) -IS - 1053-0770 (Linking) -VI - 24 -IP - 2 -DP - 2010 Apr -TI - Clinical update in cardiac imaging including echocardiography. -PG - 371-8 -LID - 10.1053/j.jvca.2009.12.018 [doi] -AB - Volumetric determinations by cardiac magnetic resonance imaging after tetralogy - of Fallot repair may more accurately assess significant right ventricular - dilation and pulmonary regurgitation to guide timing of pulmonary valve - replacement. Recent guidelines by the American and European Societies of - Echocardiography have summarized the clinical approach to valvular stenosis. They - emphasize aortic stenosis given its high incidence and assessment confounders - such as left ventricular function, aortic regurgitation, systemic hypertension, - and mitral regurgitation. The applications of 3-dimensional echocardiography have - reached transcatheter procedures such as atrial septal closure, mitral valve - repair, and aortic valve replacement. It also provides detailed assessment of the - mitral valve, cardiac chambers, and can guide pediatric aortic valve repair. The - timing of surgery in mitral regurgitation remains controversial, especially when - it is asymptomatic with normal left ventricular function. Recent data emphasize - the outcome advantage of mitral valve repair in asymptomatic mitral regurgitation - when the effective regurgitant orifice area is >40 mm(2). Transesophageal - echocardiography is an established gold standard in the assessment of - endocarditis. Multislice computed tomographic imaging has facilitated - simultaneous detailed assessment of the cardiac valves and coronary arteries. - Recent comparison has shown that these 2 imaging modalities are equivalent and - complementary. Tricuspid valve regurgitation associated with mitral disease is - common and important. At the time of mitral surgery, moderate or greater - tricuspid regurgitation should be corrected, preferably by rigid annuloplasty. - Recent evidence also supports tricuspid annuloplasty for an annular diameter >35 - mm regardless of regurgitation severity. Although repair is preferred, tricuspid - replacement also has acceptable outcomes. -CI - Copyright (c) 2010 Elsevier Inc. All rights reserved. -FAU - Ramakrishna, Harish -AU - Ramakrishna H -AD - Department of Anesthesiology, Mayo Clinic Arizona, Scottsdale, AZ, USA. -FAU - Feinglass, Neil -AU - Feinglass N -FAU - Augoustides, John G T -AU - Augoustides JG -LA - eng -PT - Journal Article -PT - Review -DEP - 20100218 -PL - United States -TA - J Cardiothorac Vasc Anesth -JT - Journal of cardiothoracic and vascular anesthesia -JID - 9110208 -SB - IM -MH - Cardiac Surgical Procedures/methods/trends -MH - Cardiovascular Diseases/*diagnostic imaging/surgery -MH - Diagnostic Imaging/methods/trends -MH - Echocardiography, Three-Dimensional/*methods/*trends -MH - Heart Valve Diseases/diagnostic imaging/surgery -MH - Humans -MH - Tetralogy of Fallot/diagnostic imaging/surgery -RF - 90 -EDAT- 2010/02/20 06:00 -MHDA- 2010/11/09 06:00 -CRDT- 2010/02/20 06:00 -PHST- 2009/12/07 00:00 [received] -PHST- 2010/02/20 06:00 [entrez] -PHST- 2010/02/20 06:00 [pubmed] -PHST- 2010/11/09 06:00 [medline] -AID - S1053-0770(09)00459-5 [pii] -AID - 10.1053/j.jvca.2009.12.018 [doi] -PST - ppublish -SO - J Cardiothorac Vasc Anesth. 2010 Apr;24(2):371-8. doi: - 10.1053/j.jvca.2009.12.018. Epub 2010 Feb 18. - -PMID- 20084002 -OWN - NLM -STAT- MEDLINE -DCOM- 20100712 -LR - 20151119 -IS - 1473-6500 (Electronic) -IS - 0952-7907 (Linking) -VI - 23 -IP - 2 -DP - 2010 Apr -TI - Outcomes in perioperative care. -PG - 201-8 -LID - 10.1097/ACO.0b013e328336aeef [doi] -AB - PURPOSE OF REVIEW: The present review examines the trends and controversies on - how perioperative care can influence outcome after anesthesia and surgery. RECENT - FINDINGS: Recent studies indicate that anesthesia and perioperative care may have - a major impact on long-term postoperative mortality and major complications in - surgical patients by decreasing the rate of individual decisions. The use of a - surgical checklist in the operating room improves postoperative mortality by - decreasing the rate of individual decisions and facilitating communication - between anesthesiologists, surgeons and intensivists. Antiplatelet therapy should - not be discontinued routinely before elective surgery in patients with coronary - or vascular occlusive disease. Attenuation of the surgical stress response by - beta-blockers decreases long-term major adverse cardiac events, but may increase - the incidence of postoperative stroke. The long-term impact on outcome of tight - glycemic control and intraoperative hemodynamic optimization requires further - investigation. SUMMARY: The use of a surgical checklist may reduce postoperative - mortality and complications in surgical patients. The optimal dosing and timing - of perioperative beta-blockade should decrease the incidence of postoperative - stroke. However, to date, the long-term risk:benefit balance of attenuation of - the perioperative stress response remains controversial. Red cell transfusion is - unavoidable in some cases, but is associated with worsened outcome in various - surgical situations. Future research should focus on the risk:benefit balance of - anesthesia and surgery. This will contribute to promoting the role of - anesthesiologists as physicians of the perioperative period. -FAU - Mantz, Jean -AU - Mantz J -AD - Department of Anesthesiology and Critical Care, Beaujon University Hospital, - Paris 7 Paris Diderot University, Clichy, France. jean.mantz@bjn.aphp.fr -FAU - Dahmani, Souhayl -AU - Dahmani S -FAU - Paugam-Burtz, Catherine -AU - Paugam-Burtz C -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Curr Opin Anaesthesiol -JT - Current opinion in anaesthesiology -JID - 8813436 -RN - 0 (Biomarkers) -RN - 0 (Blood Glucose) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Aged -MH - Biomarkers -MH - Blood Glucose/metabolism -MH - Checklist -MH - Cognition Disorders/prevention & control/psychology -MH - Erythrocyte Transfusion -MH - Heart Diseases/diagnosis/etiology -MH - Hemodynamics/physiology -MH - Humans -MH - Monitoring, Physiologic -MH - Operating Rooms/organization & administration -MH - Perioperative Care/*organization & administration -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Postoperative Complications/prevention & control/psychology -MH - Stress, Physiological/physiology -MH - Treatment Outcome -RF - 51 -EDAT- 2010/01/20 06:00 -MHDA- 2010/07/14 06:00 -CRDT- 2010/01/20 06:00 -PHST- 2010/01/20 06:00 [entrez] -PHST- 2010/01/20 06:00 [pubmed] -PHST- 2010/07/14 06:00 [medline] -AID - 10.1097/ACO.0b013e328336aeef [doi] -PST - ppublish -SO - Curr Opin Anaesthesiol. 2010 Apr;23(2):201-8. doi: 10.1097/ACO.0b013e328336aeef. - -PMID- 20020375 -OWN - NLM -STAT- MEDLINE -DCOM- 20100226 -LR - 20161125 -IS - 0171-2004 (Print) -IS - 0171-2004 (Linking) -IP - 195 -DP - 2010 -TI - Androgenic anabolic steroid abuse and the cardiovascular system. -PG - 411-57 -LID - 10.1007/978-3-540-79088-4_18 [doi] -AB - Abuse of anabolic androgenic steroids (AAS) has been linked to a variety of - different cardiovascular side effects. In case reports, acute myocardial - infarction is the most common event presented, but other adverse cardiovascular - effects such as left ventricular hypertrophy, reduced left ventricular function, - arterial thrombosis, pulmonary embolism and several cases of sudden cardiac death - have also been reported. However, to date there are no prospective, randomized, - interventional studies on the long-term cardiovascular effects of abuse of AAS. - In this review we have studied the relevant literature regarding several risk - factors for cardiovascular disease where the effects of AAS have been - scrutinized:(1) Echocardiographic studies show that supraphysiologic doses of AAS - lead to both morphologic and functional changes of the heart. These include a - tendency to produce myocardial hypertrophy (Fig. 3), a possible increase of heart - chamber diameters, unequivocal alterations of diastolic function and ventricular - relaxation, and most likely a subclinically compromised left ventricular - contractile function. (2) AAS induce a mild, but transient increase of blood - pressure. However, the clinical significance of this effect remains modest. (3) - Furthermore, AAS confer an enhanced pro-thrombotic state, most prominently - through an activation of platelet aggregability. The concomitant effects on the - humoral coagulation cascade are more complex and include activation of both - pro-coagulatory and fibrinolytic pathways. (4) Users of AAS often demonstrate - unfavorable measurements of vascular reactivity involving endothelial-dependent - or endothelial-independent vasodilatation. A degree of reversibility seems to be - consistent, though. (5) There is a comprehensive body of evidence documenting - that AAS induce various alterations of lipid metabolism. The most prominent - changes are concomitant elevations of LDL and decreases of HDL, effects that - increase the risk of coronary artery disease. And finally, (6) the use of AAS - appears to confer an increased risk of life-threatening arrhythmia leading to - sudden death, although the underlying mechanisms are still far from being - elucidated. Taken together, various lines of evidence involving a variety of - pathophysiologic mechanisms suggest an increased risk for cardiovascular disease - in users of anabolic androgenic steroids. -FAU - Vanberg, Paul -AU - Vanberg P -AD - Chief Physician/Senior Cardiologist, Oslo University Hospital - Aker, - Trondheimsveien 235, 0514-Oslo University Hospital, Oslo, Norway. - paul.vanberg@medisin.uio.no -FAU - Atar, Dan -AU - Atar D -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Handb Exp Pharmacol -JT - Handbook of experimental pharmacology -JID - 7902231 -RN - 0 (Anabolic Agents) -RN - 0 (Lipids) -RN - 0 (Steroids) -SB - IM -MH - Anabolic Agents/*adverse effects -MH - Arrhythmias, Cardiac/chemically induced -MH - Blood Platelets/drug effects -MH - Blood Vessels/diagnostic imaging/drug effects -MH - Calcinosis/chemically induced/diagnostic imaging -MH - Cardiovascular Diseases/*chemically induced/diagnostic imaging/*epidemiology -MH - Cardiovascular Physiological Phenomena/*drug effects -MH - Death, Sudden/epidemiology -MH - *Doping in Sports -MH - Echocardiography -MH - Hemostasis/drug effects -MH - Humans -MH - Lipids/blood -MH - Steroids/*adverse effects -RF - 210 -EDAT- 2009/12/19 06:00 -MHDA- 2010/02/27 06:00 -CRDT- 2009/12/19 06:00 -PHST- 2009/12/19 06:00 [entrez] -PHST- 2009/12/19 06:00 [pubmed] -PHST- 2010/02/27 06:00 [medline] -AID - 10.1007/978-3-540-79088-4_18 [doi] -PST - ppublish -SO - Handb Exp Pharmacol. 2010;(195):411-57. doi: 10.1007/978-3-540-79088-4_18. - -PMID- 23380698 -OWN - NLM -STAT- MEDLINE -DCOM- 20140422 -LR - 20230808 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 167 -IP - 5 -DP - 2013 Sep 1 -TI - Atrial fibrillation: profile and burden of an evolving epidemic in the 21st - century. -PG - 1807-24 -LID - S0167-5273(13)00004-1 [pii] -LID - 10.1016/j.ijcard.2012.12.093 [doi] -AB - BACKGROUND: Atrial fibrillation (AF) represents an increasing public health - challenge with profound social and economic implications. METHODS: A - comprehensive synthesis and review of the AF literature was performed. Overall, - key findings from 182 studies were used to describe the indicative scope and - impact of AF from an individual to population perspective. RESULTS: There are - many pathways to AF including advancing age, cardiovascular disease and increased - levels of obesity/metabolic disorders. The reported population prevalence of AF - ranges from 2.3%-3.4% and historical trends reflect increased AF incidence. - Estimated life-time risk of AF is around 1 in 4. Primary care contacts reflect - whole population trends: AF-related case-presentations increase from less than - 0.5% in those aged 40 years or less to 6-12% for those aged 85 years or more. - Globally, AF-related hospitalisations (primary or secondary diagnosis) showed an - upward trend (from ~35 to over 100 admissions/10,000 persons) during 1996 to - 2006. The estimated cost of AF is greater than 1% of health care expenditure and - rising with hospitalisations the largest contributor. For affected individuals, - quality of life indices are poor and AF confers an independent 1.5 to 2.0-fold - probability of death in the longer-term. AF is also closely linked to ischaemic - stroke (3- to 5-fold risk), chronic heart failure (up to 50% develop AF) and - acute coronary syndromes (up to 25% develop AF) with consistently worse outcomes - reported with concurrent AF. Future projections predict at least a doubling of AF - cases by 2050. SUMMARY: AF represents an evolving, global epidemic providing - considerable challenges to minimise its impact from an individual to whole - society perspective. -CI - Copyright © 2013 Elsevier Ireland Ltd. All rights reserved. -FAU - Ball, Jocasta -AU - Ball J -AD - Centre of Research Excellence to Reduce Inequality in Heart Disease, Preventative - Health, Baker IDI Heart and Diabetes Institute, Melbourne, Australia. -FAU - Carrington, Melinda J -AU - Carrington MJ -FAU - McMurray, John J V -AU - McMurray JJ -FAU - Stewart, Simon -AU - Stewart S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130204 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -SB - IM -MH - Atrial Fibrillation/*diagnosis/*epidemiology/therapy -MH - *Cost of Illness -MH - Databases, Factual/trends -MH - *Epidemics -MH - Humans -MH - Risk Factors -MH - Stroke/diagnosis/epidemiology/therapy -OTO - NOTNLM -OT - Atrial fibrillation -OT - Burden -OT - Hospitalisation -OT - Incidence -OT - Prevalence -EDAT- 2013/02/06 06:00 -MHDA- 2014/04/23 06:00 -CRDT- 2013/02/06 06:00 -PHST- 2012/06/19 00:00 [received] -PHST- 2012/12/04 00:00 [revised] -PHST- 2012/12/24 00:00 [accepted] -PHST- 2013/02/06 06:00 [entrez] -PHST- 2013/02/06 06:00 [pubmed] -PHST- 2014/04/23 06:00 [medline] -AID - S0167-5273(13)00004-1 [pii] -AID - 10.1016/j.ijcard.2012.12.093 [doi] -PST - ppublish -SO - Int J Cardiol. 2013 Sep 1;167(5):1807-24. doi: 10.1016/j.ijcard.2012.12.093. Epub - 2013 Feb 4. - -PMID- 19619327 -OWN - NLM -STAT- MEDLINE -DCOM- 20090922 -LR - 20211020 -IS - 1475-2840 (Electronic) -IS - 1475-2840 (Linking) -VI - 8 -DP - 2009 Jul 20 -TI - A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients - with heart disease. -PG - 38 -LID - 10.1186/1475-2840-8-38 [doi] -AB - Classical non-insulin antihyperglycemic drugs currently approved for the - treatment of type 2 diabetes mellitus (T2DM) comprise five groups: biguanides, - sulfonylureas, meglitinides, glitazones and alpha-glucosidase inhibitors. Novel - compounds are represented by the incretin mimetic drugs like glucagon like - peptide-1 (GLP-1), the dipeptidyl peptidase 4 (DPP-4) inhibitors, dual peroxisome - proliferator-activated receptors (PPAR) agonists (glitazars) and amylin mimetic - drugs. We review the cardiovascular effects of these drugs in an attempt to - improve knowledge regarding their potential risks when treating T2DM in cardiac - patients. Metformin may lead to lethal lactic acidosis, especially in patients - with clinical conditions that predispose to this complication, such as recent - myocardial infarction, heart or renal failure. Sulfonylureas exert their effect - by closing the ATP-dependent potassium channels. This prevents the opening of - these channels during myocardial ischemia, impeding the necessary - hyperpolarization that protects the cell. The combined sulfonylurea/metformin - therapy reveals additive effects on mortality in patients with coronary artery - disease (CAD). Meglitinides effects are similar to those of sulfonylureas, due to - their almost analogous mechanism of action. Glitazones lower leptin levels, - leading to weight gain and are unsafe in NYHA class III or IV. The long-term - effects of alpha-glucosidase inhibitors on morbidity and mortality rates is yet - unknown. The incretin GLP-1 is associated with reductions in body weight and - appears to present positive inotropic effects. DPP-4 inhibitors influences on the - cardiovascular system seem to be neutral and patients do not gain weight. The - future of glitazars is presently uncertain following concerns about their safety. - The amylin mimetic drug paramlintide, while a satisfactory adjuvant medication in - insulin-dependent diabetes, is unlikely to play a major role in the management of - T2DM. Summarizing the present information it can be stated that 1. Four out the - five classical oral antidiabetic drug groups present proven or potential cardiac - hazards; 2. These hazards are not mere 'side effects', but biochemical phenomena - which are deeply rooted in the drugs' mechanism of action; 3. Current data - indicate that the combined glibenclamide/metformin therapy seems to present - special risk and should be avoided in the long-term management of T2DM with - proven CAD; 4. Glitazones should be avoided in patients with overt heart failure; - 5, The novel incretin mimetic drugs and DPP-4 inhibitors--while usually - inadequate as monotherapy--appear to be satisfactory adjuvant drugs due to the - lack of known undesirable cardiovascular effects; 6. Customized antihyperglycemic - pharmacological approaches should be implemented for the achievement of optimal - treatment of T2DM patients with heart disease. In this context, it should be - carefully taken into consideration whether the leading clinical status is CAD or - heart failure. -FAU - Fisman, Enrique Z -AU - Fisman EZ -AD - Sackler Faculty of Medicine, Tel-Aviv University, 69978 Ramat-Aviv, Tel-Aviv, - Israel. zfisman@post.tau.ac.il -FAU - Tenenbaum, Alexander -AU - Tenenbaum A -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090720 -PL - England -TA - Cardiovasc Diabetol -JT - Cardiovascular diabetology -JID - 101147637 -RN - 0 (Cardiovascular Agents) -RN - 0 (Hypoglycemic Agents) -RN - 0 (Insulin) -SB - IM -MH - Animals -MH - Cardiovascular Agents/pharmacokinetics/*therapeutic use -MH - Diabetes Mellitus, Type 2/complications/drug therapy/mortality -MH - Heart Diseases/*drug therapy/metabolism/*mortality -MH - Humans -MH - Hypoglycemic Agents/pharmacokinetics/*therapeutic use -MH - Insulin/pharmacology/therapeutic use -MH - Survival Rate/trends -PMC - PMC2723076 -EDAT- 2009/07/22 09:00 -MHDA- 2009/09/23 06:00 -PMCR- 2009/07/20 -CRDT- 2009/07/22 09:00 -PHST- 2009/07/14 00:00 [received] -PHST- 2009/07/20 00:00 [accepted] -PHST- 2009/07/22 09:00 [entrez] -PHST- 2009/07/22 09:00 [pubmed] -PHST- 2009/09/23 06:00 [medline] -PHST- 2009/07/20 00:00 [pmc-release] -AID - 1475-2840-8-38 [pii] -AID - 10.1186/1475-2840-8-38 [doi] -PST - epublish -SO - Cardiovasc Diabetol. 2009 Jul 20;8:38. doi: 10.1186/1475-2840-8-38. - -PMID- 22923351 -OWN - NLM -STAT- MEDLINE -DCOM- 20130422 -LR - 20211021 -IS - 1573-904X (Electronic) -IS - 0724-8741 (Linking) -VI - 29 -IP - 12 -DP - 2012 Dec -TI - Inhibition of cholesterol absorption: targeting the intestine. -PG - 3235-50 -LID - 10.1007/s11095-012-0858-6 [doi] -AB - Atherosclerosis, the gradual formation of a lipid-rich plaque in the arterial - wall is the primary cause of Coronary Artery Disease (CAD), the leading cause of - mortality worldwide. Hypercholesterolemia, elevated circulating cholesterol, was - identified as a key risk factor for CAD in epidemiological studies. Since the - approval of Mevacor in 1987, the primary therapeutic intervention for - hypercholesterolemia has been statins, drugs that inhibit the biosynthesis of - cholesterol. With improved understanding of the risks associated with elevated - cholesterol levels, health agencies are recommending reductions in cholesterol - that are not achievable in every patient with statins alone, underlying the need - for improved combination therapies. The whole body cholesterol pool is derived - from two sources, biosynthesis and diet. Although statins are effective at - reducing the biosynthesis of cholesterol, they do not inhibit the absorption of - cholesterol, making this an attractive target for adjunct therapies. This report - summarizes the efforts to target the gastrointestinal absorption of cholesterol, - with emphasis on specifically targeting the gastrointestinal tract to avoid the - off-target effects sometimes associated with systemic exposure. -FAU - Lee, Stephen D -AU - Lee SD -AD - Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East - Mall, Vancouver, British Columbia, V6T 1Z3, Canada. Stephen.Lee@alumni.ubc.ca -FAU - Gershkovich, Pavel -AU - Gershkovich P -FAU - Darlington, Jerald W -AU - Darlington JW -FAU - Wasan, Kishor M -AU - Wasan KM -LA - eng -GR - Canadian Institutes of Health Research/Canada -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120825 -PL - United States -TA - Pharm Res -JT - Pharmaceutical research -JID - 8406521 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Apolipoproteins B) -RN - 0 (Azetidines) -RN - 0 (Bile Acids and Salts) -RN - 0 (Liver X Receptors) -RN - 0 (Orphan Nuclear Receptors) -RN - 0 (Phytosterols) -RN - 97C5T2UQ7J (Cholesterol) -RN - EC 2.3.1.26 (Sterol O-Acyltransferase) -RN - EOR26LQQ24 (Ezetimibe) -SB - IM -MH - Animals -MH - Anticholesteremic Agents/chemistry/pharmacology/*therapeutic use -MH - Apolipoproteins B/genetics/metabolism -MH - Atherosclerosis/drug therapy/metabolism -MH - Azetidines/chemistry/pharmacology/therapeutic use -MH - Bile Acids and Salts/metabolism -MH - Cholesterol/*metabolism -MH - Ezetimibe -MH - Heart Diseases/drug therapy/metabolism -MH - Humans -MH - Intestinal Absorption/*drug effects -MH - Liver X Receptors -MH - Molecular Targeted Therapy/*methods -MH - Orphan Nuclear Receptors/agonists -MH - Phytosterols/chemistry/pharmacology/therapeutic use -MH - Sterol O-Acyltransferase/antagonists & inhibitors/metabolism -MH - Transcription, Genetic/drug effects -EDAT- 2012/08/28 06:00 -MHDA- 2013/04/23 06:00 -CRDT- 2012/08/28 06:00 -PHST- 2012/05/10 00:00 [received] -PHST- 2012/08/06 00:00 [accepted] -PHST- 2012/08/28 06:00 [entrez] -PHST- 2012/08/28 06:00 [pubmed] -PHST- 2013/04/23 06:00 [medline] -AID - 10.1007/s11095-012-0858-6 [doi] -PST - ppublish -SO - Pharm Res. 2012 Dec;29(12):3235-50. doi: 10.1007/s11095-012-0858-6. Epub 2012 Aug - 25. - -PMID- 21718583 -OWN - NLM -STAT- MEDLINE -DCOM- 20160422 -LR - 20250626 -IS - 1752-8526 (Electronic) -VI - 2010 -DP - 2010 Feb 25 -TI - Heart failure. -LID - 0204 [pii] -AB - INTRODUCTION: Heart failure occurs in 3% to 4% of adults aged over 65 years, - usually as a consequence of coronary artery disease or hypertension, and causes - breathlessness, effort intolerance, fluid retention, and increased mortality. The - 5-year mortality in people with systolic heart failure ranges from 25% to 75%, - often owing to sudden death following ventricular arrhythmia. Risks of - cardiovascular events are increased in people with left ventricular systolic - dysfunction (LVSD) or heart failure. METHODS AND OUTCOMES: We conducted a - systematic review and aimed to answer the following clinical questions: What are - the effects of non-drug treatments, and of drug and invasive treatments, for - heart failure? What are the effects of angiotensin-converting enzyme inhibitors - in people at high risk of heart failure? What are the effects of treatments for - diastolic heart failure? We searched: Medline, Embase, The Cochrane Library, and - other important databases up to May 2009 (Clinical Evidence reviews are updated - periodically; please check our website for the most up-to-date version of this - review). We included harms alerts from relevant organisations such as the US Food - and Drug Administration (FDA) and the UK Medicines and Healthcare products - Regulatory Agency (MHRA). RESULTS: We found 85 systematic reviews, RCTs, or - observational studies that met our inclusion criteria. We performed a GRADE - evaluation of the quality of evidence for interventions. CONCLUSIONS: In this - systematic review we present information relating to the effectiveness and safety - of the following interventions: aldosterone receptor antagonists; amiodarone; - angiotensin-converting enzyme inhibitors; angiotensin II receptor blockers; - anticoagulation; antiplatelet agents; beta-blockers; calcium channel blockers; - cardiac resynchronisation therapy; digoxin (in people already receiving diuretics - and angiotensin-converting enzyme inhibitors); exercise; hydralazine plus - isosorbide dinitrate; implantable cardiac defibrillators; multidisciplinary - interventions; non-amiodarone antiarrhythmic drugs; and positive inotropes (other - than digoxin). -FAU - McKelvie, Robert Samuel -AU - McKelvie RS -AD - McMaster University, Hamilton, ON, Canada. -LA - eng -PT - Journal Article -PT - Systematic Review -DEP - 20100225 -PL - England -TA - BMJ Clin Evid -JT - BMJ clinical evidence -JID - 101294314 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Mineralocorticoid Receptor Antagonists) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - *Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - *Heart Failure -MH - Humans -MH - Mineralocorticoid Receptor Antagonists/therapeutic use -MH - Treatment Outcome -MH - Ventricular Dysfunction, Left/drug therapy -PMC - PMC2907608 -EDAT- 2010/01/01 00:00 -MHDA- 2016/04/23 06:00 -PMCR- 2012/02/25 -CRDT- 2011/07/02 06:00 -PHST- 2011/07/02 06:00 [entrez] -PHST- 2010/01/01 00:00 [pubmed] -PHST- 2016/04/23 06:00 [medline] -PHST- 2012/02/25 00:00 [pmc-release] -AID - 0204 [pii] -PST - epublish -SO - BMJ Clin Evid. 2010 Feb 25;2010:0204. - -PMID- 16960505 -OWN - NLM -STAT- MEDLINE -DCOM- 20061120 -LR - 20121115 -IS - 0957-9672 (Print) -IS - 0957-9672 (Linking) -VI - 17 -IP - 5 -DP - 2006 Oct -TI - Do metalloproteinases destabilize vulnerable atherosclerotic plaques? -PG - 556-61 -AB - PURPOSE OF REVIEW: Atherosclerotic plaque rupture and thrombosis underlie most - myocardial infarctions. Matrix metalloproteinases are a family of enzymes that - remodel the extracellular matrix. Metalloproteinases could stabilize - rupture-prone plaques by promoting smooth muscle cell migration and - proliferation. Alternatively, metalloproteinases could destabilize vulnerable - plaques by promoting matrix destruction, angiogenesis, leucocyte infiltration, - and apoptosis. Evidence is reviewed from genetically modified mice and human - biomarker and genetic studies that sheds light on this dual role of - metalloproteinases. RECENT FINDINGS: Inhibition of metalloproteinases in mice - using tissue inhibitors of metalloproteinases increases plaque stability; - however, double knockouts of apolipoprotein E with matrix metalloproteinase 2, 3, - 7, 9, 12, and 13 have more or less stable plaques, consistent with harmful or - protective effects of individual metalloproteinases. Overexpression studies in - mice or rabbits show that high activities of matrix metalloproteinase 9 and 12 - decrease stability. Biomarker and human genetic studies demonstrate that - increased metalloproteinase activity is associated with vascular repair or - myocardial infarction. SUMMARY: Recent studies reinforce evidence for a dual role - of matrix metalloproteinases in plaque stabilization and rupture, which probably - depends on the stage, site, and severity of disease. Dysregulated - metalloproteinase activity in end-stage coronary artery disease appears a valid - target for therapy. -FAU - Newby, Andrew C -AU - Newby AC -AD - Bristol Heart Institute, Royal Infirmary, University of Bristol, Bristol BS2 8HW, - UK. A.Newby@bris.ac.uk -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Curr Opin Lipidol -JT - Current opinion in lipidology -JID - 9010000 -RN - 0 (Matrix Metalloproteinase Inhibitors) -RN - 0 (Protease Inhibitors) -RN - EC 3.4.24.- (Matrix Metalloproteinases) -SB - IM -MH - Animals -MH - Atherosclerosis/drug therapy/*enzymology/etiology -MH - Humans -MH - Matrix Metalloproteinase Inhibitors -MH - Matrix Metalloproteinases/deficiency/genetics/*metabolism -MH - Mice -MH - Mice, Knockout -MH - Models, Biological -MH - Protease Inhibitors/therapeutic use -RF - 37 -EDAT- 2006/09/09 09:00 -MHDA- 2006/12/09 09:00 -CRDT- 2006/09/09 09:00 -PHST- 2006/09/09 09:00 [pubmed] -PHST- 2006/12/09 09:00 [medline] -PHST- 2006/09/09 09:00 [entrez] -AID - 00041433-200610000-00010 [pii] -AID - 10.1097/01.mol.0000245262.48258.b4 [doi] -PST - ppublish -SO - Curr Opin Lipidol. 2006 Oct;17(5):556-61. doi: - 10.1097/01.mol.0000245262.48258.b4. - -PMID- 19691483 -OWN - NLM -STAT- MEDLINE -DCOM- 20100302 -LR - 20230829 -IS - 1538-7836 (Electronic) -IS - 1538-7836 (Linking) -VI - 7 -IP - 11 -DP - 2009 Nov -TI - Platelet functions beyond hemostasis. -PG - 1759-66 -LID - 10.1111/j.1538-7836.2009.03586.x [doi] -AB - Although their central role is in the prevention of bleeding, platelets probably - contribute to diverse processes that extend beyond hemostasis and thrombosis. For - example, platelets can recruit leukocytes and progenitor cells to sites of - vascular injury and inflammation; they release proinflammatory and - anti-inflammatory and angiogenic factors and microparticles into the circulation; - and they spur thrombin generation. Data from animal models suggest that these - functions may contribute to atherosclerosis, sepsis, hepatitis, vascular - restenosis, acute lung injury, and transplant rejection. This article represents - an integrated summary of presentations given at the Fourth Annual Platelet - Colloquium in January 2009. The process of and factors mediating - platelet-platelet and platelet-leukocyte interactions in inflammatory and immune - responses are discussed, with the roles of P-selectin, chemokines and Src family - kinases being highlighted. Also discussed are specific disorders characterized by - local or systemic platelet activation, including coronary artery restenosis after - percutaneous intervention, alloantibody-mediated transplant rejection, wound - healing, and heparin-induced thrombocytopenia. -FAU - Smyth, S S -AU - Smyth SS -AD - Lexington VA Medical Center and Division of Cardiovascular Medicine, Gill Heart - Institute, University of Kentucky, Lexington, KY 40536, USA. susansmyth@uky.edu -FAU - McEver, R P -AU - McEver RP -FAU - Weyrich, A S -AU - Weyrich AS -FAU - Morrell, C N -AU - Morrell CN -FAU - Hoffman, M R -AU - Hoffman MR -FAU - Arepally, G M -AU - Arepally GM -FAU - French, P A -AU - French PA -FAU - Dauerman, H L -AU - Dauerman HL -FAU - Becker, R C -AU - Becker RC -CN - 2009 Platelet Colloquium Participants -LA - eng -PT - Journal Article -PT - Review -DEP - 20090819 -PL - England -TA - J Thromb Haemost -JT - Journal of thrombosis and haemostasis : JTH -JID - 101170508 -SB - IM -MH - Blood Platelets/chemistry/pathology/*physiology -MH - Cell Communication -MH - Disease/etiology -MH - Humans -MH - Immunity -MH - Inflammation -RF - 58 -FIR - Arepally, Gowthami M -IR - Arepally GM -FIR - Becker, Richard C -IR - Becker RC -FIR - Bhatt, Deepak L -IR - Bhatt DL -FIR - Cho, Jaehyung -IR - Cho J -FIR - Dauerman, Harold L -IR - Dauerman HL -FIR - Gretler, Daniel D -IR - Gretler DD -FIR - Hoffman, Maureane R -IR - Hoffman MR -FIR - Horrow, Jay -IR - Horrow J -FIR - Kleiman, Neal S -IR - Kleiman NS -FIR - Kocharian, Richard -IR - Kocharian R -FIR - Lincoff, A Michael -IR - Lincoff AM -FIR - Maya, Juan -IR - Maya J -FIR - McEver, Rodger P -IR - McEver RP -FIR - Morrell, Craig N -IR - Morrell CN -FIR - Prats, Jayne -IR - Prats J -FIR - Rusconi, Christopher P -IR - Rusconi CP -FIR - Smyth, Susan S -IR - Smyth SS -FIR - Strony, John -IR - Strony J -FIR - Sun, Henry -IR - Sun H -FIR - Veltri, Enrico P -IR - Veltri EP -FIR - Weyrich, Andrew S -IR - Weyrich AS -FIR - Wiviott, Stephen D -IR - Wiviott SD -FIR - Wood, Jeremy P -IR - Wood JP -EDAT- 2009/08/21 09:00 -MHDA- 2010/03/03 06:00 -CRDT- 2009/08/21 09:00 -PHST- 2009/08/21 09:00 [entrez] -PHST- 2009/08/21 09:00 [pubmed] -PHST- 2010/03/03 06:00 [medline] -AID - S1538-7836(22)10607-0 [pii] -AID - 10.1111/j.1538-7836.2009.03586.x [doi] -PST - ppublish -SO - J Thromb Haemost. 2009 Nov;7(11):1759-66. doi: 10.1111/j.1538-7836.2009.03586.x. - Epub 2009 Aug 19. - -PMID- 19187003 -OWN - NLM -STAT- MEDLINE -DCOM- 20100218 -LR - 20211020 -IS - 1557-7716 (Electronic) -IS - 1523-0864 (Print) -IS - 1523-0864 (Linking) -VI - 11 -IP - 8 -DP - 2009 Aug -TI - Therapeutic angiogenesis in diabetes and hypercholesterolemia: influence of - oxidative stress. -PG - 1945-59 -AB - Despite significant improvements in the medical, percutaneous, and surgical - management, numerous patients are first seen with non-revascularizable coronary - artery disease (CAD). The growth of new blood vessels to improve myocardial - perfusion (i.e., therapeutic angiogenesis) is an attractive treatment option for - these patients. However, the successes of angiogenic therapy, observed in - preclinical studies, have not been realized in clinical trials. Increasing - evidence suggests that this discrepancy between animal and human studies may be - due to the nature of the substrate, or the molecular and cellular environment - within which the angiogenic agent acts. Antiangiogenic influences, including - endothelial dysfunction, hypercholesterolemia, and diabetes, are present in - virtually all patients with advanced CAD. Recent studies have better - characterized the abnormalities associated with these disease states, providing - novel targets for intervention. These substrate-modifying interventions can - potentially enhance the response to protein-, gene-, or cell-based angiogenic - therapy. In this review, we discuss key aspects of the angiogenic process and the - pathophysiologic and molecular mechanisms that contribute to an impaired - angiogenic response in the setting of endothelial dysfunction, - hypercholesterolemia, and diabetes, with a focus on the role of oxidative stress. - Last, we briefly explore substrate modifying agents that have been evaluated in - preclinical and clinical studies to improve the angiogenic response. -FAU - Boodhwani, Munir -AU - Boodhwani M -AD - Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, - Canada. -FAU - Sellke, Frank W -AU - Sellke FW -LA - eng -GR - R01 HL069024/HL/NHLBI NIH HHS/United States -GR - R01 HL69024/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Review -PL - United States -TA - Antioxid Redox Signal -JT - Antioxidants & redox signaling -JID - 100888899 -SB - IM -MH - Animals -MH - Blood Vessels/*growth & development -MH - Diabetes Mellitus/*therapy -MH - Humans -MH - Hypercholesterolemia/*therapy -MH - *Oxidative Stress -MH - Signal Transduction -PMC - PMC2848518 -EDAT- 2009/02/04 09:00 -MHDA- 2010/02/19 06:00 -PMCR- 2010/08/01 -CRDT- 2009/02/04 09:00 -PHST- 2009/02/04 09:00 [entrez] -PHST- 2009/02/04 09:00 [pubmed] -PHST- 2010/02/19 06:00 [medline] -PHST- 2010/08/01 00:00 [pmc-release] -AID - 10.1089/ARS.2009.2439 [pii] -AID - 10.1089/ars.2009.2439 [pii] -AID - 10.1089/ars.2009.2439 [doi] -PST - ppublish -SO - Antioxid Redox Signal. 2009 Aug;11(8):1945-59. doi: 10.1089/ars.2009.2439. - -PMID- 17717209 -OWN - NLM -STAT- MEDLINE -DCOM- 20070918 -LR - 20220310 -IS - 1526-7598 (Electronic) -IS - 0003-2999 (Linking) -VI - 105 -IP - 3 -DP - 2007 Sep -TI - Perioperative echocardiographic examination for ventricular assist device - implantation. -PG - 583-601 -AB - Ventricular assist devices (VADs) are systems for mechanical circulatory support - of the patient with severe heart failure. Perioperative transesophageal - echocardiography is a major component of patient management, and important for - surgical and anesthetic decision making. In this review we present the rationale - and available data for a comprehensive echocardiographic assessment of patients - receiving a VAD. In addition to the standard examination, device-specific pre-, - intra-, and postoperative considerations are essential to the echocardiographic - evaluation. These include: (a) the pre-VAD insertion examination of the heart and - large vessels to exclude significant aortic regurgitation, tricuspid - regurgitation, mitral stenosis, patent foramen ovale, or other cardiac - abnormality that could lead to right-to-left shunt after left VAD placement, - intracardiac thrombi, ventricular scars, pulmonic regurgitation, pulmonary - hypertension, pulmonary embolism, and atherosclerotic disease in the ascending - aorta; and to assess right ventricular function; and (b) the post-VAD insertion - examination of the device and reassessment of the heart and large vessels. The - examination of the device aims to confirm completeness of device and heart - deairing, cannulas alignment and patency, and competency of device valves using - two-dimensional, and color, continuous and pulsed wave Doppler modalities. The - goal for the heart examination after implantation should be to exclude aortic - regurgitation, or an uncovered right-to-left shunt; and to assess right - ventricular function, left ventricular unloading, and the effect of device - settings on global heart function. The variety of VAD models with different basic - and operation principles requires specific echocardiographic assessment targeted - to the characteristics of the implanted device. -FAU - Chumnanvej, Siriluk -AU - Chumnanvej S -AD - Department of Anesthesia and Critical Care, Massachusetts General Hospital and - Harvard Medical School, Boston, Massachusetts 02114, USA. -FAU - Wood, Malissa J -AU - Wood MJ -FAU - MacGillivray, Thomas E -AU - MacGillivray TE -FAU - Melo, Marcos F Vidal -AU - Melo MF -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Anesth Analg -JT - Anesthesia and analgesia -JID - 1310650 -SB - IM -CIN - Anesth Analg. 2008 Feb;106(2):673-4; author reply 674. doi: - 10.1213/ane.0b013e318160fdde. PMID: 18227340 -MH - Aorta/diagnostic imaging -MH - Coronary Circulation -MH - Device Removal -MH - *Echocardiography, Doppler, Color -MH - *Echocardiography, Transesophageal -MH - Equipment Design -MH - Equipment Failure -MH - Heart Defects, Congenital/complications/diagnostic imaging -MH - Heart Failure/*complications/*diagnostic imaging/physiopathology/therapy -MH - Heart Valve Diseases/complications/diagnostic imaging -MH - Heart Valves/diagnostic imaging -MH - Heart Ventricles/diagnostic imaging -MH - *Heart-Assist Devices/adverse effects -MH - Humans -MH - Microbubbles/adverse effects -MH - Perioperative Care/*methods -MH - Severity of Illness Index -MH - Treatment Outcome -MH - Ventricular Function -RF - 152 -EDAT- 2007/08/25 09:00 -MHDA- 2007/09/19 09:00 -CRDT- 2007/08/25 09:00 -PHST- 2007/08/25 09:00 [pubmed] -PHST- 2007/09/19 09:00 [medline] -PHST- 2007/08/25 09:00 [entrez] -AID - 105/3/583 [pii] -AID - 10.1213/01.ane.0000278088.22952.82 [doi] -PST - ppublish -SO - Anesth Analg. 2007 Sep;105(3):583-601. doi: 10.1213/01.ane.0000278088.22952.82. - -PMID- 18042058 -OWN - NLM -STAT- MEDLINE -DCOM- 20080219 -LR - 20161124 -IS - 0896-4327 (Print) -IS - 0896-4327 (Linking) -VI - 20 -IP - 6 -DP - 2007 Dec -TI - Transcatheter closure of intracardiac defects in adults. -PG - 524-45 -AB - There has been a dramatic increase in the adult congenital heart disease - population and appreciation of intracardiac shunt lesions discovered or acquired - in adults over the past several years. Fortunately, this increase has been met - with advances in imaging modalities, which permit a more accurate noninvasive - assessment of cardiac defects. Additionally, the evolutions in both device - technology as well as fluoroscopic and echocardiographic image guidance have - permitted the safe and effective catheter-based closure of numerous intracardiac - defects. With catheter-based closure procedures now considered the treatment of - choice in most cases of intracardiac defect repair in adults, it is imperative - that clinicians possess a sound understanding of intracardiac shunt lesions and - indications for repair or closure so that they may better care for this unique - subset of adult patients. This review will focus on the anatomy, pathophysiology, - and current transcatheter therapeutic options for adult patients with patent - foramen ovale (PFO), atrial septal defects (ASD), and ventricular septal defects - (VSD). -FAU - Kim, Michael S -AU - Kim MS -AD - Department of Medicine, University of Colorado Health Sciences Center, Aurora, - Colorado, USA. -FAU - Klein, Andrew J -AU - Klein AJ -FAU - Carroll, John D -AU - Carroll JD -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Interv Cardiol -JT - Journal of interventional cardiology -JID - 8907826 -SB - IM -MH - Adult -MH - *Cardiac Catheterization/methods -MH - Clinical Competence -MH - Coronary Circulation -MH - Embolism, Paradoxical/etiology -MH - Heart Atria/diagnostic imaging -MH - Heart Septal Defects/physiopathology/*therapy -MH - Heart Septal Defects, Atrial/classification/complications/surgery/therapy -MH - Heart Septal Defects, Ventricular/diagnostic imaging/therapy -MH - Humans -MH - Migraine Disorders/etiology -MH - Patient Selection -MH - *Prostheses and Implants -MH - Prosthesis Design -MH - Prosthesis Implantation/methods -MH - Randomized Controlled Trials as Topic -MH - Tomography, X-Ray Computed -MH - Ultrasonography -RF - 135 -EDAT- 2007/11/29 09:00 -MHDA- 2008/02/20 09:00 -CRDT- 2007/11/29 09:00 -PHST- 2007/11/29 09:00 [pubmed] -PHST- 2008/02/20 09:00 [medline] -PHST- 2007/11/29 09:00 [entrez] -AID - JOIC304 [pii] -AID - 10.1111/j.1540-8183.2007.00304.x [doi] -PST - ppublish -SO - J Interv Cardiol. 2007 Dec;20(6):524-45. doi: 10.1111/j.1540-8183.2007.00304.x. - -PMID- 20673125 -OWN - NLM -STAT- MEDLINE -DCOM- 20110803 -LR - 20181201 -IS - 1557-7716 (Electronic) -IS - 1523-0864 (Linking) -VI - 14 -IP - 9 -DP - 2011 May 1 -TI - Nitroxyl (HNO) as a vasoprotective signaling molecule. -PG - 1675-86 -LID - 10.1089/ars.2010.3327 [doi] -AB - Nitroxyl (HNO), the one electron reduced and protonated form of nitric oxide - (NO(•)), is rapidly emerging as a novel nitrogen oxide with distinct pharmacology - and therapeutic advantages over its redox sibling. Whilst the cardioprotective - effects of HNO in heart failure have been established, it is apparent that HNO - may also confer a number of vasoprotective properties. Like NO(•), HNO induces - vasodilatation, inhibits platelet aggregation, and limits vascular smooth muscle - cell proliferation. In addition, HNO can be putatively generated within the - vasculature, and recent evidence suggests it also serves as an - endothelium-derived relaxing factor (EDRF). Significantly, HNO targets signaling - pathways distinct from NO(•) with an ability to activate K(V) and K(ATP) channels - in resistance arteries, cause coronary vasodilatation in part via release of - calcitonin-gene related peptide (CGRP), and exhibits resistance to scavenging by - superoxide and vascular tolerance development. As such, HNO synthesis and - bioavailability may be preserved and/or enhanced during disease states, in - particular those associated with oxidative stress. Moreover, it may compensate, - in part, for a loss of NO(•) signaling. Here we explore the vasoprotective - actions of HNO and discuss the therapeutic potential of HNO donors in the - treatment of vascular dysfunction. -FAU - Bullen, Michelle L -AU - Bullen ML -AD - Vascular Biology and Immunopharmacology Group, Department of Pharmacology, Monash - University, Clayton, Victoria, Australia. -FAU - Miller, Alyson A -AU - Miller AA -FAU - Andrews, Karen L -AU - Andrews KL -FAU - Irvine, Jennifer C -AU - Irvine JC -FAU - Ritchie, Rebecca H -AU - Ritchie RH -FAU - Sobey, Christopher G -AU - Sobey CG -FAU - Kemp-Harper, Barbara K -AU - Kemp-Harper BK -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20101102 -PL - United States -TA - Antioxid Redox Signal -JT - Antioxidants & redox signaling -JID - 100888899 -RN - 0 (Endothelium-Dependent Relaxing Factors) -RN - 0 (Nitrogen Oxides) -RN - GFQ4MMS07W (nitroxyl) -RN - JHB2QIZ69Z (Calcitonin Gene-Related Peptide) -SB - IM -MH - Animals -MH - Calcitonin Gene-Related Peptide/metabolism -MH - Endothelium-Dependent Relaxing Factors/metabolism -MH - Humans -MH - Models, Biological -MH - Nitrogen Oxides/*metabolism -MH - Signal Transduction -MH - Vasodilation -EDAT- 2010/08/03 06:00 -MHDA- 2011/08/04 06:00 -CRDT- 2010/08/03 06:00 -PHST- 2010/08/03 06:00 [entrez] -PHST- 2010/08/03 06:00 [pubmed] -PHST- 2011/08/04 06:00 [medline] -AID - 10.1089/ars.2010.3327 [doi] -PST - ppublish -SO - Antioxid Redox Signal. 2011 May 1;14(9):1675-86. doi: 10.1089/ars.2010.3327. Epub - 2010 Nov 2. - -PMID- 22519444 -OWN - NLM -STAT- MEDLINE -DCOM- 20130703 -LR - 20190907 -IS - 1873-4294 (Electronic) -IS - 1568-0266 (Linking) -VI - 12 -IP - 10 -DP - 2012 -TI - Inflammatory mechanisms in atherosclerosis: the impact of matrix - metalloproteinases. -PG - 1132-48 -AB - Inflammatory process is essential for the initiation and progression of vascular - remodeling, entailing degradation and reorganization of the extra-cellular matrix - (ECM) scaffold of the vessel wall, leading to the development of atherosclerotic - lesions. Matrix metalloproteinases (MMPs) are zing dependent endo-peptidases - found in most living organisms and act mainly by degrading ECM components. Most - MMPs are formed as inactive proenzymes and are activated by proteolysis. This - process depends and is regulated by other proteases and endogenous MMP inhibitors - (TIMPs). MMPs and TIMPs play a major role not only in ECM degradation but also in - mediating cell migration, proliferation, tissue remodeling; acting as a signal - for the production and secretion of growth factors and cytokines. More - importantly MMPs through proteolysis and degradation of ECM contribute in many - physiological and pathological processes including organ development, wound - healing, tissue support, vascular remodeling and restenosis, atherosclerosis - progression, acute coronary syndromes, myocardial infarction, cardiomyopathy, - aneurysms remodeling, cancer, arthritis, and chronic inflammatory diseases. A - substantial body of evidence support the notion that imbalance between the - activity of MMPs and their tissue inhibitors (TIMPs) contribute to the - pathogenesis of cardiovascular diseases such as atherosclerosis, vascular - remodeling and progression of heart failure. In this review, we will discuss the - relationship between MMPs, inflammation and atherosclerosis under the topic of - cardiovascular disease. -FAU - Siasos, Gerasimos -AU - Siasos G -AD - Department of Biological Chemistry, University of Athens Medical School, Athens, - Greece. gsiasos@med.uoa.gr -FAU - Tousoulis, Dimitris -AU - Tousoulis D -FAU - Kioufis, Stamatios -AU - Kioufis S -FAU - Oikonomou, Evangelos -AU - Oikonomou E -FAU - Siasou, Zoi -AU - Siasou Z -FAU - Limperi, Maria -AU - Limperi M -FAU - Papavassiliou, Athanasios G -AU - Papavassiliou AG -FAU - Stefanadis, Christodoulos -AU - Stefanadis C -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Top Med Chem -JT - Current topics in medicinal chemistry -JID - 101119673 -RN - 0 (Enzyme Inhibitors) -RN - 0 (Matrix Metalloproteinase Inhibitors) -RN - EC 3.4.24.- (Matrix Metalloproteinases) -SB - IM -MH - Atherosclerosis/enzymology/*metabolism -MH - Cardiovascular Diseases/enzymology/metabolism -MH - Enzyme Inhibitors/metabolism -MH - Extracellular Matrix/*enzymology/metabolism -MH - Humans -MH - Inflammation/*metabolism -MH - Matrix Metalloproteinase Inhibitors -MH - Matrix Metalloproteinases/*metabolism -MH - Models, Biological -EDAT- 2012/04/24 06:00 -MHDA- 2013/07/05 06:00 -CRDT- 2012/04/24 06:00 -PHST- 2011/09/02 00:00 [received] -PHST- 2011/10/20 00:00 [revised] -PHST- 2011/11/02 00:00 [accepted] -PHST- 2012/04/24 06:00 [entrez] -PHST- 2012/04/24 06:00 [pubmed] -PHST- 2013/07/05 06:00 [medline] -AID - CTMC-EPUB-20120420-004 [pii] -AID - 10.2174/1568026611208011132 [doi] -PST - ppublish -SO - Curr Top Med Chem. 2012;12(10):1132-48. doi: 10.2174/1568026611208011132. - -PMID- 19443933 -OWN - NLM -STAT- MEDLINE -DCOM- 20090714 -LR - 20200106 -IS - 1734-1140 (Print) -IS - 1734-1140 (Linking) -VI - 61 -IP - 2 -DP - 2009 Mar-Apr -TI - Pharmacology of dimethyl sulfoxide in cardiac and CNS damage. -PG - 225-35 -AB - The pharmacological effects of dimethyl sulfoxide (DMSO) administration include - some desirable properties that may be useful in the treatment of medical - disorders resulting in tissue injury and compromised organ systems. These - properties include the reported effects of DMSO on impaired blood flow, - suppression of cytotoxicity from excess glutamate release that may result in - lethal NMDA-AMPA activation, restriction of cytotoxic Na(+) and Ca(2+) entry into - damaged cells, blocking tissue factor (TF) from contributing to thrombosis, - reduction of intracranial pressure, tissue edema, and inflammatory reactions, and - inhibition of vascular smooth muscle cell migration and proliferation that can - lead to atherosclerosis of the coronary, peripheral, and cerebral circulation. A - review of the basic and clinical literature on the biological actions of DMSO in - cardiac and central nervous system (CNS) damage or dysfunction indicates that - this agent, alone or in combination with other synergistic molecules, has been - reported to neutralize or attenuate pathological complications that harmed or can - further harm these two organ systems. The effects of DMSO make it potentially - useful in the treatment of medical disorders involving head and spinal cord - injury, stroke, memory dysfunction, and ischemic heart disease. -FAU - Jacob, Stanley W -AU - Jacob SW -AD - Department of Surgery, Oregon Health & Science University, Portland, OR 97201, - USA. -FAU - de la Torre, Jack C -AU - de la Torre JC -LA - eng -PT - Journal Article -PT - Review -PL - Switzerland -TA - Pharmacol Rep -JT - Pharmacological reports : PR -JID - 101234999 -RN - YOW8V9698H (Dimethyl Sulfoxide) -SB - IM -MH - Animals -MH - Brain Injuries/*drug therapy -MH - Dimethyl Sulfoxide/pharmacology/*therapeutic use/toxicity -MH - Humans -MH - Memory Disorders/drug therapy -MH - Myocardial Ischemia/*drug therapy -MH - Spinal Cord Injuries/*drug therapy -MH - Stroke/*drug therapy -RF - 78 -EDAT- 2009/05/16 09:00 -MHDA- 2009/07/15 09:00 -CRDT- 2009/05/16 09:00 -PHST- 2008/07/23 00:00 [received] -PHST- 2009/02/20 00:00 [revised] -PHST- 2009/05/16 09:00 [entrez] -PHST- 2009/05/16 09:00 [pubmed] -PHST- 2009/07/15 09:00 [medline] -AID - S1734-1140(09)70026-X [pii] -AID - 10.1016/s1734-1140(09)70026-x [doi] -PST - ppublish -SO - Pharmacol Rep. 2009 Mar-Apr;61(2):225-35. doi: 10.1016/s1734-1140(09)70026-x. - -PMID- 22401038 -OWN - NLM -STAT- MEDLINE -DCOM- 20120920 -LR - 20250626 -IS - 1366-5804 (Electronic) -IS - 1354-750X (Linking) -VI - 17 -IP - 4 -DP - 2012 Jun -TI - Lipoprotein-associated phospholipase A2 (Lp-PLA2): a review of its role and - significance as a cardiovascular biomarker. -PG - 289-302 -LID - 10.3109/1354750X.2012.664170 [doi] -AB - OBJECTIVE: To conduct a comprehensive, systematic review of studies assessing the - significance of lipoprotein-associated phospholipase A2 in cardiovascular - diseases (CVDs). MATERIAL AND METHODS: A review of the literature was performed - using the search term "Lipoprotein-associated phospholipase A2 (Lp-PLA2)" and - each of the following terms: "cardiovascular risk," "cardiovascular death," - "atherosclerotic disease," "coronary events," "transient ischemic attack (TIA)," - "stroke," and "heart failure." The searches were performed on Medline, Google - Scholar and ClinicalTrials.gov. RESULTS: The majority of published studies showed - a significant association between Lp-PLA2 levels and cardiovascular events after - multivariate adjustment. The association was consistent across a wide variety of - subjects of both sexes and different ethnic backgrounds. CONCLUSIONS: The role of - Lp-PLA2 as a significant biomarker of vascular inflammation was confirmed, and - Lp-PLA2 seems to be closely correlated to cardiovascular events. It may be an - important therapeutic target and may have an important role in prevention, risk - stratification and personalised medicine. -FAU - Vittos, Oana -AU - Vittos O -AD - Medcenter, Cardiology, Bucharest, Romania. oanatoana@yahoo.com -FAU - Toana, Bogdan -AU - Toana B -FAU - Vittos, Alexandros -AU - Vittos A -FAU - Moldoveanu, Elena -AU - Moldoveanu E -LA - eng -PT - Journal Article -PT - Systematic Review -DEP - 20120309 -PL - England -TA - Biomarkers -JT - Biomarkers : biochemical indicators of exposure, response, and susceptibility to - chemicals -JID - 9606000 -RN - 0 (Biomarkers) -RN - 0 (Inflammation Mediators) -RN - 0 (Lipoproteins) -RN - EC 3.1.1.47 (1-Alkyl-2-acetylglycerophosphocholine Esterase) -SB - IM -MH - 1-Alkyl-2-acetylglycerophosphocholine Esterase/metabolism/*physiology -MH - Biomarkers/metabolism -MH - Cardiovascular Diseases/*enzymology/therapy -MH - Humans -MH - Inflammation Mediators/metabolism/physiology -MH - Lipoproteins/metabolism/physiology -MH - Molecular Targeted Therapy -MH - Oxidative Stress -EDAT- 2012/03/10 06:00 -MHDA- 2012/09/21 06:00 -CRDT- 2012/03/10 06:00 -PHST- 2012/03/10 06:00 [entrez] -PHST- 2012/03/10 06:00 [pubmed] -PHST- 2012/09/21 06:00 [medline] -AID - 10.3109/1354750X.2012.664170 [doi] -PST - ppublish -SO - Biomarkers. 2012 Jun;17(4):289-302. doi: 10.3109/1354750X.2012.664170. Epub 2012 - Mar 9. - -PMID- 20465096 -OWN - NLM -STAT- MEDLINE -DCOM- 20100601 -LR - 20100514 -IS - 0042-773X (Print) -IS - 0042-773X (Linking) -VI - 56 -IP - 4 -DP - 2010 Apr -TI - [Diabetes mellitus and prothrombotic activity]. -PG - 284-8 -AB - Diabetes mellitus (DM) is defined by significant hyperglycaemia representing a - high risk of thrombosis in coronary as well as central and peripheral arteries. - The risk of myocardial infarction in patients with type 2 diabetes is 3-5 times - higher than in non-diabetics. This is consequent to changes in haemostasis in - obese patients with type 2 diabetes, including changes to fibrinolysis, decreased - fibrinolytic activity and increased thrombogenic risk, as part of the - pluri-metabolic insulin resistance syndrome. The REACH study evaluated more than - 67 thousands of patients with a risk of arterial thrombosis or with arterial - thrombosis. The patients with diabetes were separated and the results subjected - to multivariate analysis; differences were confirmed between intensity of - treatment in patients with ischemic heart disease and diabetes and with diabetes - only. Antithrombotic therapy in diabetic patients with no clinical signs of - arterial thrombosis was less intensive. -FAU - Malý, J -AU - Malý J -AD - II. interní klinika Lékarské fakulty UK a FN Hradec Králové. maly@fnhk.cz -LA - cze -PT - English Abstract -PT - Journal Article -PT - Review -TT - Diabetes mellitus a protrombotická aktivita. -PL - Czech Republic -TA - Vnitr Lek -JT - Vnitrni lekarstvi -JID - 0413602 -SB - IM -MH - Blood Coagulation -MH - Diabetes Mellitus, Type 2/*blood/complications/physiopathology -MH - Fibrinolysis -MH - Humans -MH - Insulin Resistance -MH - Obesity/blood/complications/physiopathology -MH - Thrombosis/blood/complications/*physiopathology -RF - 34 -EDAT- 2010/05/15 06:00 -MHDA- 2010/06/02 06:00 -CRDT- 2010/05/15 06:00 -PHST- 2010/05/15 06:00 [entrez] -PHST- 2010/05/15 06:00 [pubmed] -PHST- 2010/06/02 06:00 [medline] -PST - ppublish -SO - Vnitr Lek. 2010 Apr;56(4):284-8. - -PMID- 19944955 -OWN - NLM -STAT- MEDLINE -DCOM- 20100222 -LR - 20220408 -IS - 1097-6795 (Electronic) -IS - 0894-7317 (Linking) -VI - 22 -IP - 12 -DP - 2009 Dec -TI - Echocardiographic epicardial fat: a review of research and clinical applications. -PG - 1311-9; quiz 1417-8 -LID - 10.1016/j.echo.2009.10.013 [doi] -AB - Epicardial fat plays a role in cardiovascular diseases. Because of its anatomic - and functional proximity to the myocardium and its intense metabolic activity, - some interactions between the heart and its visceral fat depot have been - suggested. Epicardial fat can be visualized and measured using standard - two-dimensional echocardiography. Standard parasternal long-axis and short-axis - views permit the most accurate measurement of epicardial fat thickness overlying - the right ventricle. Epicardial fat thickness is generally identified as the - echo-free space between the outer wall of the myocardium and the visceral layer - of pericardium and is measured perpendicularly on the free wall of the right - ventricle at end-systole. Echocardiographic epicardial fat thickness ranges from - a minimum of 1 mm to a maximum of almost 23 mm. Echocardiographic epicardial fat - thickness clearly reflects visceral adiposity rather than general obesity. It - correlates with metabolic syndrome, insulin resistance, coronary artery disease, - and subclinical atherosclerosis, and therefore it might serve as a simple tool - for cardiometabolic risk prediction. Substantial changes in echocardiographic - epicardial fat thickness during weight-loss strategies may also suggest its use - as a marker of therapeutic effect. Echocardiographic epicardial fat measurement - in both clinical and research scenarios has several advantages, including its low - cost, easy accessibility, rapid applicability, and good reproducibility. However, - more evidence is necessary to evaluate whether echocardiographic epicardial fat - thickness may become a routine way of assessing cardiovascular risk in a clinical - setting. -FAU - Iacobellis, Gianluca -AU - Iacobellis G -AD - Department of Medicine, Division of Endocrinology, McMaster University, Ontario, - Canada. gianluca@ccc.mcmaster.ca -FAU - Willens, Howard J -AU - Willens HJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Am Soc Echocardiogr -JT - Journal of the American Society of Echocardiography : official publication of the - American Society of Echocardiography -JID - 8801388 -SB - IM -MH - Adipose Tissue/*diagnostic imaging -MH - Biomedical Research/*methods -MH - Echocardiography/*methods -MH - Humans -MH - Image Enhancement/*methods -MH - Pericardium/*diagnostic imaging -RF - 77 -EDAT- 2009/12/01 06:00 -MHDA- 2010/02/23 06:00 -CRDT- 2009/12/01 06:00 -PHST- 2009/12/01 06:00 [entrez] -PHST- 2009/12/01 06:00 [pubmed] -PHST- 2010/02/23 06:00 [medline] -AID - S0894-7317(09)00996-1 [pii] -AID - 10.1016/j.echo.2009.10.013 [doi] -PST - ppublish -SO - J Am Soc Echocardiogr. 2009 Dec;22(12):1311-9; quiz 1417-8. doi: - 10.1016/j.echo.2009.10.013. - -PMID- 19016575 -OWN - NLM -STAT- MEDLINE -DCOM- 20090227 -LR - 20211020 -IS - 0012-6667 (Print) -IS - 0012-6667 (Linking) -VI - 68 -IP - 17 -DP - 2008 -TI - Ranolazine: a review of its use in chronic stable angina pectoris. -PG - 2483-503 -LID - 10.2165/0003495-200868170-00006 [doi] -AB - Extended-release ranolazine (ranolazine ER) [Ranexa] is a piperazine derivative - with a novel mechanism of action that was recently approved in the EU for use as - add-on therapy in patients with stable angina pectoris. Ranolazine ER achieves - its antianginal effect without affecting heart rate or blood pressure (BP) to a - clinically significant extent. Results of well designed, placebo-controlled, - short-term studies demonstrate that add-on therapy with ranolazine ER in patients - with chronic stable angina improves exercise performance, and reduces anginal - frequency and nitroglycerin use. Although longer-term therapy with ranolazine ER - did not reduce the incidence of major cardiovascular events in patients with - non-ST-elevation acute coronary syndromes, it did reduce the incidence of - recurrent ischaemia. Ranolazine ER is a generally well tolerated antianginal - agent. Although it is associated with modest dose-related increases in the - corrected QT (QTc) interval, ranolazine ER does not appear to be associated with - an excess of arrhythmias. Thus, ranolazine ER is a useful new option for patients - with chronic stable angina whose symptoms are not controlled with first-line - antianginal therapy or who do not tolerate first-line antianginal agents. -FAU - Keating, Gillian M -AU - Keating GM -AD - Wolters Kluwer Health | Adis, Auckland, New Zealand. demail@adis.co.nz -LA - eng -PT - Journal Article -PT - Review -PL - New Zealand -TA - Drugs -JT - Drugs -JID - 7600076 -RN - 0 (Acetanilides) -RN - 0 (Cardiovascular Agents) -RN - 0 (Delayed-Action Preparations) -RN - 0 (Piperazines) -RN - A6IEZ5M406 (Ranolazine) -SB - IM -EIN - Drugs. 2011 Jul 9;71(10):1332 -MH - *Acetanilides/pharmacology/therapeutic use -MH - Angina Pectoris/*drug therapy -MH - *Cardiovascular Agents/pharmacology/therapeutic use -MH - Chronic Disease -MH - Delayed-Action Preparations -MH - Humans -MH - *Piperazines/pharmacology/therapeutic use -MH - Ranolazine -RF - 74 -EDAT- 2008/11/20 09:00 -MHDA- 2009/02/28 09:00 -CRDT- 2008/11/20 09:00 -PHST- 2008/11/20 09:00 [pubmed] -PHST- 2009/02/28 09:00 [medline] -PHST- 2008/11/20 09:00 [entrez] -AID - 68176 [pii] -AID - 10.2165/0003495-200868170-00006 [doi] -PST - ppublish -SO - Drugs. 2008;68(17):2483-503. doi: 10.2165/0003495-200868170-00006. - -PMID- 18367036 -OWN - NLM -STAT- MEDLINE -DCOM- 20080515 -LR - 20211020 -IS - 1534-6293 (Electronic) -IS - 1528-4042 (Linking) -VI - 8 -IP - 1 -DP - 2008 Jan -TI - Use of antiplatelet agents to prevent stroke: what is the role for combinations - of medications? -PG - 29-34 -AB - Antiplatelet agents are the medications of choice for preventing - non-cardioembolic strokes. The diverse pathways involved in platelet function - suggest the possibility of synergistic effects by combining various agents. In - heart disease and in the setting of coronary artery stents, antiplatelet therapy - with clopidogrel and aspirin has established benefits. Although it is tempting to - extrapolate the benefits of this combination for stroke prevention, recent - clinical trials have not borne this out. Unacceptable bleeding risks without - additional efficacy weigh against the routine use of clopidogrel with aspirin for - stroke prophylaxis. The combination of aspirin and extended-release dipyridamole - has demonstrated superiority over aspirin in two large secondary stroke - prevention trials. -FAU - Schwartz, Neil E -AU - Schwartz NE -AD - Stanford Stroke Center, Department of Neurology and Neurological Sciences, - Stanford University, 701 Welch Road, #B325, Palo Alto, CA 94304, USA. - neuro1@stanford.edu -FAU - Albers, Gregory W -AU - Albers GW -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Neurol Neurosci Rep -JT - Current neurology and neuroscience reports -JID - 100931790 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 64ALC7F90C (Dipyridamole) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Aspirin/administration & dosage/adverse effects -MH - Clinical Trials as Topic/statistics & numerical data -MH - Clopidogrel -MH - Dipyridamole/administration & dosage/adverse effects -MH - Drug Interactions/physiology -MH - Drug Therapy, Combination -MH - Hemorrhage/chemically induced/physiopathology -MH - Humans -MH - Platelet Aggregation Inhibitors/*administration & dosage/*adverse effects -MH - Risk Assessment -MH - Stroke/*drug therapy/physiopathology/*prevention & control -MH - Ticlopidine/administration & dosage/adverse effects/analogs & derivatives -RF - 49 -EDAT- 2008/03/28 09:00 -MHDA- 2008/05/16 09:00 -CRDT- 2008/03/28 09:00 -PHST- 2008/03/28 09:00 [pubmed] -PHST- 2008/05/16 09:00 [medline] -PHST- 2008/03/28 09:00 [entrez] -AID - 10.1007/s11910-008-0006-1 [doi] -PST - ppublish -SO - Curr Neurol Neurosci Rep. 2008 Jan;8(1):29-34. doi: 10.1007/s11910-008-0006-1. - -PMID- 17975472 -OWN - NLM -STAT- MEDLINE -DCOM- 20080206 -LR - 20220409 -IS - 0192-0790 (Print) -IS - 0192-0790 (Linking) -VI - 41 Suppl 3 -DP - 2007 Nov-Dec -TI - Vascular deterioration in cirrhosis: the big picture. -PG - S247-53 -AB - Cirrhosis is characterized by marked abnormalities in the hepatic circulation. - Functionally, there is an increased vascular tone and impaired flow-mediated - vasorelaxation, whereas anatomically there is sinusoidal remodeling and - capillarization, angiogenesis, venous thrombosis, and vascular distortion, all - contributing to increase hepatic vascular resistance and portal hypertension. - However, vascular changes are not limited to the liver, but are also present in - the splanchnic organs, heart, lungs, kidney, brain, and skin. Advances in the - knowledge of the mechanisms of these abnormalities have disclosed new targets for - therapy and ultimately improved survival. -FAU - Bosch, Jaime -AU - Bosch J -AD - Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic-Idibaps, University - of Barcelona and Centro de Investigación Biomédica de Enfermedades Hepáticas y - Digestivas (Ciberehd), Barcelona, Spain. jbosch@clinic.ub.es -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Clin Gastroenterol -JT - Journal of clinical gastroenterology -JID - 7910017 -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Animals -MH - Antihypertensive Agents/therapeutic use -MH - Cerebrovascular Circulation -MH - Collateral Circulation -MH - Coronary Circulation -MH - Disease Progression -MH - Endothelium, Vascular/metabolism/pathology/*physiopathology -MH - Extracellular Matrix/metabolism -MH - Humans -MH - Hypertension, Portal/*etiology/metabolism/pathology/physiopathology/therapy -MH - Inflammation/physiopathology -MH - Insulin Resistance -MH - Liver/*blood supply/metabolism/pathology/physiopathology -MH - Liver Circulation -MH - Liver Cirrhosis/complications/metabolism/pathology/*physiopathology/therapy -MH - Neovascularization, Pathologic/physiopathology -MH - Oxidative Stress -MH - Portal Pressure -MH - Pulmonary Circulation -MH - Renal Circulation -MH - Skin/blood supply -MH - *Splanchnic Circulation -MH - Treatment Outcome -MH - Vascular Resistance -MH - Vasodilation -RF - 49 -EDAT- 2007/12/06 09:00 -MHDA- 2008/02/07 09:00 -CRDT- 2007/12/06 09:00 -PHST- 2007/12/06 09:00 [pubmed] -PHST- 2008/02/07 09:00 [medline] -PHST- 2007/12/06 09:00 [entrez] -AID - 00004836-200711001-00003 [pii] -AID - 10.1097/MCG.0b013e3181572357 [doi] -PST - ppublish -SO - J Clin Gastroenterol. 2007 Nov-Dec;41 Suppl 3:S247-53. doi: - 10.1097/MCG.0b013e3181572357. - -PMID- 23590705 -OWN - NLM -STAT- MEDLINE -DCOM- 20130606 -LR - 20131121 -IS - 1753-4887 (Electronic) -IS - 0029-6643 (Linking) -VI - 71 -IP - 5 -DP - 2013 May -TI - Effect of garlic on serum lipids: an updated meta-analysis. -PG - 282-99 -LID - 10.1111/nure.12012 [doi] -AB - Hypercholesterolemia is associated with an increased risk of heart disease. The - effect of garlic on blood lipids has been studied in numerous trials and - summarized in meta-analyses, with conflicting results. This meta-analysis, the - most comprehensive to date, includes 39 primary trials of the effect of garlic - preparations on total cholesterol, low-density lipoprotein cholesterol, - high-density lipoprotein cholesterol, and triglycerides. The findings suggest - garlic to be effective in reducing total serum cholesterol by 17 ± 6 mg/dL and - low-density lipoprotein cholesterol by 9 ± 6 mg/dL in individuals with elevated - total cholesterol levels (>200 mg/dL), provided garlic is used for longer than 2 - months. An 8% reduction in total serum cholesterol is of clinical relevance and - is associated with a 38% reduction in risk of coronary events at 50 years of age. - High-density lipoprotein cholesterol levels improved only slightly, and - triglycerides were not influenced significantly. Garlic preparations were highly - tolerable in all trials and were associated with minimal side effects. They might - be considered as an alternative option with a higher safety profile than - conventional cholesterol-lowering medications in patients with slightly elevated - cholesterol. -CI - © 2013 International Life Sciences Institute. -FAU - Ried, Karin -AU - Ried K -AD - Discipline of General Practice, The University of Adelaide, Adelaide, South - Australia, Australia. karinried@niim.com.au -FAU - Toben, Catherine -AU - Toben C -FAU - Fakler, Peter -AU - Fakler P -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130307 -PL - United States -TA - Nutr Rev -JT - Nutrition reviews -JID - 0376405 -RN - 0 (Anticholesteremic Agents) -RN - 0 (Plant Extracts) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Anticholesteremic Agents/*therapeutic use -MH - Cholesterol/blood -MH - Garlic/*chemistry -MH - Humans -MH - Hypercholesterolemia/blood/*therapy -MH - *Phytotherapy -MH - Plant Extracts/*therapeutic use -MH - Treatment Outcome -EDAT- 2013/04/18 06:00 -MHDA- 2013/06/07 06:00 -CRDT- 2013/04/18 06:00 -PHST- 2013/04/18 06:00 [entrez] -PHST- 2013/04/18 06:00 [pubmed] -PHST- 2013/06/07 06:00 [medline] -AID - 10.1111/nure.12012 [doi] -PST - ppublish -SO - Nutr Rev. 2013 May;71(5):282-99. doi: 10.1111/nure.12012. Epub 2013 Mar 7. - -PMID- 19273219 -OWN - NLM -STAT- MEDLINE -DCOM- 20090407 -LR - 20220227 -IS - 2768-6698 (Electronic) -IS - 2768-6698 (Linking) -VI - 14 -IP - 7 -DP - 2009 Jan 1 -TI - Role of Toll-like receptor mediated signaling pathway in ischemic heart. -PG - 2553-8 -LID - 10.2741/3397 [doi] -AB - Stimulation of TLRs by exogenous and endogenous ligands triggers expression of - several genes that are involved in innate immune responses. Recently, a role of - TLR4 in the myocardial response to injury separate from microbial pathogens has - been examined in experimental studies. TLR4 deficient mice sustain significantly - smaller infarctions compared with wild-type control mice given similar areas at - risk. Levels of serum cytokines such as IL-1b, IL-6, and TNFa are increased after - ischemia/reperfusion, but these responses are attenuated in TLR4 deficient mice - compared to control mice. TLR2 signaling also importantly contributes to cardiac - dysfunction following ischemia/reperfusion. MyD88, a key adaptor protein for TLR - signaling, is responsible for the protective effects of TLR signaling inhibition - in ischemia/reperfusion injury. TLR4 gene polymorphism (Asp299Gly) attenuates - innate immune responsiveness, reduces the risk for coronary artery disease, and - increases a chance of longevity. The innate immune system is clearly involved in - the pathogenesis of cardiovascular diseases and could be a new therapeutic - target. -FAU - Takeishi, Yasuchika -AU - Takeishi Y -AD - First Department of Internal Medicine, Fukushima Medical University, Fukushima, - Japan. takeishi@fmu.ac.jp -FAU - Kubota, Isao -AU - Kubota I -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20090101 -PL - Singapore -TA - Front Biosci (Landmark Ed) -JT - Frontiers in bioscience (Landmark edition) -JID - 101612996 -RN - 0 (MYD88 protein, human) -RN - 0 (Myeloid Differentiation Factor 88) -RN - 0 (Toll-Like Receptors) -SB - IM -MH - Humans -MH - Myeloid Differentiation Factor 88/metabolism -MH - Myocardial Ischemia/metabolism/*physiopathology -MH - Myocardium/metabolism -MH - Polymorphism, Genetic -MH - Signal Transduction/*physiology -MH - Toll-Like Receptors/genetics/metabolism/*physiology -RF - 36 -EDAT- 2009/03/11 09:00 -MHDA- 2009/04/08 09:00 -CRDT- 2009/03/11 09:00 -PHST- 2009/03/11 09:00 [entrez] -PHST- 2009/03/11 09:00 [pubmed] -PHST- 2009/04/08 09:00 [medline] -AID - 3397 [pii] -AID - 10.2741/3397 [doi] -PST - epublish -SO - Front Biosci (Landmark Ed). 2009 Jan 1;14(7):2553-8. doi: 10.2741/3397. - -PMID- 18449380 -OWN - NLM -STAT- MEDLINE -DCOM- 20080605 -LR - 20211020 -IS - 1934-1997 (Electronic) -IS - 1934-1997 (Linking) -VI - 10 Suppl -IP - Supp -DP - 2008 Mar 26 -TI - Cardiac and vascular protection: the potential of ONTARGET. -PG - S7 -AB - Cardiovascular risk is determined by multiple risk factors. Blockade of the - renin-angiotensin system is an important approach to the prevention of - cardiovascular events. In the largest angiotensin receptor blocker cardiovascular - outcome study to date, the ONgoing Telmisartan Alone and in combination with - Ramipril Global Endpoint Trial (ONTARGET) program will compare the efficacy of - therapy with telmisartan and ramipril, in reducing cardiovascular events in - patients at high risk (history of coronary artery disease, stroke or transient - ischemic attack, peripheral artery disease, or diabetes with evidence of - end-organ damage). Recruited patients (n = 31,546) will be followed up for a - period of 6 years, and more than 150,000 patient-years of data will be recorded. - The primary endpoint is a composite of cardiovascular death, stroke, acute - myocardial infarction, and hospitalization for congestive heart failure; - secondary endpoints focus on reductions in newly diagnosed heart failure, - new-onset type 2 diabetes, cognitive decline, atrial fibrillation, and - nephropathy. In addition, an ambulatory blood pressure monitoring substudy will - be conducted to assess the effect of treatment on endpoints after adjustment for - 24-hour blood pressure values. Other substudies of the treatment effects on - erectile dysfunction, blood markers, arterial stiffness, oral glucose tolerance, - and the progression of target organ damage are also planned. The results of the - ONTARGET program are due in 2008, and the findings are expected to have important - clinical implications for the management of patients at high cardiovascular risk. -FAU - Mancia, Giuseppe -AU - Mancia G -AD - Department of Medicine, University of Milano-Bicocca, San Gerardo Hospital, - Monza, Milan, Italy. giuseppe.mancia@unimib.it -FAU - Jakobsen, Anne -AU - Jakobsen A -FAU - Heroys, Jose -AU - Heroys J -FAU - Ralph, Ann -AU - Ralph A -FAU - Rees, Tomas -AU - Rees T -FAU - Shaw, Michael -AU - Shaw M -LA - eng -PT - Journal Article -PT - Review -DEP - 20080326 -PL - United States -TA - Medscape J Med -JT - Medscape journal of medicine -JID - 101462763 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Benzimidazoles) -RN - 0 (Benzoates) -RN - 0 (Cardiotonic Agents) -RN - L35JN3I7SJ (Ramipril) -RN - U5SYW473RQ (Telmisartan) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/*administration & dosage -MH - Angiotensin-Converting Enzyme Inhibitors/*administration & dosage -MH - Benzimidazoles/*administration & dosage -MH - Benzoates/*administration & dosage -MH - Cardiotonic Agents/*administration & dosage -MH - Cardiovascular Diseases/*prevention & control -MH - *Clinical Trials as Topic -MH - Drug Delivery Systems/methods -MH - Drug Therapy, Combination -MH - Humans -MH - Ramipril/*administration & dosage -MH - Telmisartan -MH - Treatment Outcome -PMC - PMC2344118 -EDAT- 2008/05/09 09:00 -MHDA- 2008/06/06 09:00 -PMCR- 2008/01/01 -CRDT- 2008/05/09 09:00 -PHST- 2008/05/09 09:00 [pubmed] -PHST- 2008/06/06 09:00 [medline] -PHST- 2008/05/09 09:00 [entrez] -PHST- 2008/01/01 00:00 [pmc-release] -AID - 569164 [pii] -PST - epublish -SO - Medscape J Med. 2008 Mar 26;10 Suppl(Supp):S7. - -PMID- 17170605 -OWN - NLM -STAT- MEDLINE -DCOM- 20070417 -LR - 20211217 -IS - 1524-6175 (Print) -IS - 1751-7176 (Electronic) -IS - 1524-6175 (Linking) -VI - 8 -IP - 12 Suppl 4 -DP - 2006 Dec -TI - Targeting nitric oxide with drug therapy. -PG - 40-52 -AB - Increasing knowledge of the role of nitric oxide (NO) in physiology and disease - has stimulated efforts to target the NO pathway pharmacologically. These - therapeutic strategies include NO donors that directly or indirectly release NO - and agents that increase NO bioactivity. Traditional organic nitrates such as - nitroglycerin, which indirectly release NO, were believed to have limited - long-term efficacy and tolerability, chiefly because of nitrate tolerance. Recent - studies, however, suggest more effective ways of using these agents and new - applications for them. Nicorandil, a hybrid organic nitrate that also activates - potassium channels, has demonstrated significant benefits in acute coronary - syndromes. Other nitrates are being investigated for use in neurodegenerative - diseases. Direct NO donors include NO gas, which is useful in respiratory - disorders, and the more recent classes of diazeniumdiolates, sydnonimines, and - S-nitrosothiols. Preliminary data suggest that these agents may be effective as - antiatherosclerotic agents as well as in other disease states. In addition, - hybrid agents that consist of an NO donor coupled with a parent anti-inflammatory - drug, including nonsteroidal anti-inflammatory drugs, have demonstrated enhanced - efficacy and tolerability compared with the anti-inflammatory parent drug alone - in diverse experimental models. Established drugs that enhance NO bioactivity - include antihypertensive agents, particularly angiotensin-converting enzyme - inhibitors, calcium channel blockers, and newer vasodilating beta-blockers. In - addition, 3-methylglutaryl coenzyme A reductase inhibitors (statins) promote NO - bioactivity, both through and independent of lipid lowering. The NO-promoting - actions of these established drugs provide some insight into their known benefits - and suggest possible therapeutic potential. -FAU - Mason, R Preston -AU - Mason RP -AD - Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, - Boston, MA, USA. rpmason@elucidaresearch.com -FAU - Cockcroft, John R -AU - Cockcroft JR -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Clin Hypertens (Greenwich) -JT - Journal of clinical hypertension (Greenwich, Conn.) -JID - 100888554 -RN - 0 (Adrenergic alpha-Antagonists) -RN - 0 (Angiotensin Receptor Antagonists) -RN - 0 (Antihypertensive Agents) -RN - 0 (Benzopyrans) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Carbazoles) -RN - 0 (Ethanolamines) -RN - 0 (Nitrates) -RN - 0 (Nitric Oxide Donors) -RN - 0 (Propanolamines) -RN - 0 (Vasodilator Agents) -RN - 030Y90569U (Nebivolol) -RN - 0K47UL67F2 (Carvedilol) -RN - 260456HAM0 (Nicorandil) -RN - 31C4KY9ESH (Nitric Oxide) -RN - IA7306519N (Isosorbide Dinitrate) -SB - IM -MH - Adrenergic alpha-Antagonists/pharmacology/therapeutic use -MH - Angiotensin Receptor Antagonists -MH - Antihypertensive Agents/pharmacology/therapeutic use -MH - Benzopyrans/pharmacology/therapeutic use -MH - Biological Availability -MH - Calcium Channel Blockers/pharmacology/therapeutic use -MH - Carbazoles/therapeutic use -MH - Carvedilol -MH - Ethanolamines/pharmacology/therapeutic use -MH - Heart Diseases/drug therapy -MH - Humans -MH - Isosorbide Dinitrate/therapeutic use -MH - Nebivolol -MH - Neurodegenerative Diseases/drug therapy -MH - Nicorandil/therapeutic use -MH - Nitrates/therapeutic use -MH - Nitric Oxide/metabolism/*physiology -MH - Nitric Oxide Donors/pharmacology/*therapeutic use -MH - Propanolamines/therapeutic use -MH - Vasodilator Agents/therapeutic use -PMC - PMC8109704 -EDAT- 2006/12/16 09:00 -MHDA- 2007/04/18 09:00 -PMCR- 2008/07/16 -CRDT- 2006/12/16 09:00 -PHST- 2006/12/16 09:00 [pubmed] -PHST- 2007/04/18 09:00 [medline] -PHST- 2006/12/16 09:00 [entrez] -PHST- 2008/07/16 00:00 [pmc-release] -AID - JCH6041 [pii] -AID - 10.1111/j.1524-6175.2006.06041.x [doi] -PST - ppublish -SO - J Clin Hypertens (Greenwich). 2006 Dec;8(12 Suppl 4):40-52. doi: - 10.1111/j.1524-6175.2006.06041.x. - -PMID- 18996825 -OWN - NLM -STAT- MEDLINE -DCOM- 20090420 -LR - 20210204 -IS - 1934-2403 (Electronic) -IS - 1530-891X (Linking) -VI - 14 -IP - 7 -DP - 2008 Oct -TI - Diabetes: a cardiac condition manifesting as hyperglycemia. -PG - 924-32 -AB - OBJECTIVE: To investigate the reasons for the increased risk of cardiovascular - events and mortality in individuals with type 2 diabetes mellitus. METHODS: From - January 1990 to March 2008, literature relevant to low-density lipoprotein (LDL) - and high-density lipoprotein (HDL) cholesterol, hemoglobin A1c, acute - hyperglycemia, postprandial hyperglycemia, systolic blood pressure, insulin - resistance, endothelial dysfunction, microalbuminuria, diabetic cardiomyopathy, - left ventricular hypertrophy, function inhibitors of the renin-angiotensin system - and sympathetic nervous system, statins, and antiplatelet therapy as related to - cardiac events and mortality in type 2 diabetic patients was reviewed. RESULTS: - Increased numbers of cardiac events and mortality in type 2 diabetes are - associated with low HDL and high LDL cholesterol, high hemoglobin A1c, and high - systolic blood pressure. Acute hyperglycemia, postprandial hyperglycemia, and - possibly use of traditional sulfonylureas also increase incidence of cardiac - events and mortality. The presence of microalbuminuria signifies endothelial - dysfunction and an increased risk of cardiac events. Hypertension should be - treated to goals that are lower in the diabetic patient with multiple therapies, - which include suppressors of the renin-angiotensin and sympathetic nervous - systems. Decreased improvement in outcomes for the diabetic patient with - cardiovascular disease may be accounted for by the failure to treat insulin - resistance and ventricular dysfunction. The high incidence of heart failure in - the diabetic patient is due to the toxic triad of diabetic cardiomyopathy, left - ventricular hypertrophy, and extensive coronary artery disease. CONCLUSION: High - risk of cardiovascular events, heart failure, and mortality in type 2 diabetes - can be lowered with risk factor reduction and therapies that prevent or improve - ventricular function. -FAU - Bell, David S H -AU - Bell DS -AD - University of Alabama School of Medicine, Birmingham, AL, USA. dshbell@yahoo.com -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Endocr Pract -JT - Endocrine practice : official journal of the American College of Endocrinology - and the American Association of Clinical Endocrinologists -JID - 9607439 -SB - IM -MH - Cardiovascular Diseases/*etiology/*metabolism/prevention & control -MH - Diabetes Mellitus, Type 2/complications/*metabolism/*pathology -MH - Humans -MH - Hyperglycemia/*metabolism/pathology/*physiopathology -MH - Risk Factors -RF - 75 -EDAT- 2008/11/11 09:00 -MHDA- 2009/04/21 09:00 -CRDT- 2008/11/11 09:00 -PHST- 2008/11/11 09:00 [pubmed] -PHST- 2009/04/21 09:00 [medline] -PHST- 2008/11/11 09:00 [entrez] -AID - S1530-891X(20)41322-9 [pii] -AID - 10.4158/EP.14.7.924 [doi] -PST - ppublish -SO - Endocr Pract. 2008 Oct;14(7):924-32. doi: 10.4158/EP.14.7.924. - -PMID- 23819168 -OWN - NLM -STAT- MEDLINE -DCOM- 20130719 -LR - 20130702 -IS - 1167-7422 (Print) -IS - 1167-7422 (Linking) -VI - 22 -IP - 138 -DP - 2013 May -TI - Pirfenidone. First, do no harm. -PG - 117-9 -AB - Idiopathic pulmonary fibrosis is a rare disorder due to progressive, widespread - fibrotic damage of the lung parenchyma. It usually occurs after the age of 50, - and its cause is unknown. Symptoms include progressive shortness of breath and - nonproductive cough. The course of the disease is marked by exacerbations. Death - from respiratory failure occurs about 2 to 5 years after diagnosis. There are - currently no drugs that can control or slow the fibrotic process. Pirfenidone, an - immunosuppressant, has been authorised in the European Union for the treatment of - mild to moderate idiopathic pulmonary fibrosis. Clinical evaluation is based on - two double-blind randomised placebo-controlled trials lasting 72 weeks in a total - of 779 patients. Mortality, the frequency of exacerbations and the number of lung - transplants did not differ significantly between the pirfenidone and placebo - groups in either trial. Decline in forced vital capacity was smaller with - pirfenidone than with placebo, but the difference was statistically significant - in only one of the trials. The small difference in this surrogate endpoint is of - questionable clinical relevance. 14.8% of the patients taking pirfenidone 2403 - mg/day (maintenance dose according to the marketing authorisation) discontinued - treatment because of adverse events, versus 8.6% of patients in the placebo - groups. Serious adverse effects included 3 cases of bladder cancer in the - pirfenidone groups versus 1 case in the placebo groups. Photosensitivity and skin - rash, cardiac arrhythmias and coronary artery disease were more frequent with - pirfenidone 2403 mg/day than with placebo. Abnormal transaminase elevation - occurred in 4.1% of patients on pirfenidone 2403 mg/day versus 0.6% of patients - on placebo. A few cases of acute renal failure were also observed. In practice, - there is no evidence that pirfenidone improves quality of life in patients with - mild to moderate idiopathic pulmonary fibrosis, or that it slows the progression - of pulmonary fibrosis. The adverse effect profile is already burdensome. Pending - real therapeutic advance, it is best to avoid pirfenidone altogether and to focus - on symptomatic treatment. -LA - eng -PT - Journal Article -PT - Review -PL - France -TA - Prescrire Int -JT - Prescrire international -JID - 9439295 -RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) -RN - 0 (Pyridones) -RN - D7NLD2JX7U (pirfenidone) -MH - Anti-Inflammatory Agents, Non-Steroidal/*adverse effects/*therapeutic use -MH - Heart Diseases/chemically induced -MH - Humans -MH - Pulmonary Fibrosis/*drug therapy -MH - Pyridones/*adverse effects/*therapeutic use -MH - Risk Assessment -EDAT- 2013/07/03 06:00 -MHDA- 2013/07/20 06:00 -CRDT- 2013/07/03 06:00 -PHST- 2013/07/03 06:00 [entrez] -PHST- 2013/07/03 06:00 [pubmed] -PHST- 2013/07/20 06:00 [medline] -PST - ppublish -SO - Prescrire Int. 2013 May;22(138):117-9. - -PMID- 22827290 -OWN - NLM -STAT- MEDLINE -DCOM- 20130820 -LR - 20250529 -IS - 1875-6182 (Electronic) -IS - 1871-5257 (Linking) -VI - 10 -IP - 4 -DP - 2012 Dec -TI - Cardiac protection via metabolic modulation: an emerging role for incretin-based - therapies? -PG - 319-24 -AB - Cardiovascular disease continues to be a major cause of morbidity and mortality - in patients with Type 2 Diabetes Mellitus. Whilst a focus on improved glucose - control and HbA1c has led to a reduction in the progression and development of - microvascular complications, the potential for this strategy to reduce - cardiovascular event rates is less clearly defined. Identification of the - incretin axis has facilitated the development of several novel therapeutic agents - which target glucagon-like peptide-1 (GLP-1) pathways. The effects on glucose - homeostasis are now established, but there is also now an increasing body of - evidence to support a number of pleiotropic effects on the heart that may have - the potential to influence cardiovascular outcomes. In this article, we review - myocardial energy metabolism with particular emphasis on the potential benefits - associated with a shift towards increased glucose utilisation and present the - pre-clinical and clinical evidence regarding incretin effects on the heart. In - addition we discuss the potential mechanism of action and benefit of drugs that - modulate GLP-1 in patients with type 2 diabetes mellitus and coronary artery - disease. -FAU - McCormick, Liam M -AU - McCormick LM -AD - Department of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK. -FAU - Kydd, Anna C -AU - Kydd AC -FAU - Dutka, David P -AU - Dutka DP -LA - eng -GR - G1000479/MRC_/Medical Research Council/United Kingdom -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiovasc Hematol Agents Med Chem -JT - Cardiovascular & hematological agents in medicinal chemistry -JID - 101266881 -RN - 0 (Cardiotonic Agents) -RN - 0 (Incretins) -RN - 89750-14-1 (Glucagon-Like Peptide 1) -SB - IM -MH - Animals -MH - Cardiotonic Agents/*pharmacology/therapeutic use -MH - Cardiovascular Diseases/*prevention & control -MH - Diabetes Mellitus, Type 2/*drug therapy/metabolism -MH - Energy Metabolism -MH - Glucagon-Like Peptide 1/*analogs & derivatives/pharmacology/therapeutic use -MH - Humans -MH - Incretins/*pharmacology -MH - Myocardium/*metabolism -EDAT- 2012/07/26 06:00 -MHDA- 2013/08/21 06:00 -CRDT- 2012/07/26 06:00 -PHST- 2012/01/25 00:00 [received] -PHST- 2012/06/01 00:00 [revised] -PHST- 2012/06/01 00:00 [accepted] -PHST- 2012/07/26 06:00 [entrez] -PHST- 2012/07/26 06:00 [pubmed] -PHST- 2013/08/21 06:00 [medline] -AID - CMCCHA-EPUB-20120723-3 [pii] -AID - 10.2174/187152512803530360 [doi] -PST - ppublish -SO - Cardiovasc Hematol Agents Med Chem. 2012 Dec;10(4):319-24. doi: - 10.2174/187152512803530360. - -PMID- 20645988 -OWN - NLM -STAT- MEDLINE -DCOM- 20120325 -LR - 20220408 -IS - 1755-5922 (Electronic) -IS - 1755-5914 (Linking) -VI - 29 -IP - 6 -DP - 2011 Dec -TI - There is more to life than revascularization: therapeutic targeting of myocardial - ischemia/reperfusion injury. -PG - e67-79 -LID - 10.1111/j.1755-5922.2010.00190.x [doi] -AB - Ischemic heart disease is the world's leading cause of death, and while clinical - advances have meant improved and more rapid revascularization, there remains a - significant element of myocardial death that thus far has not been successfully - targeted in clinical practice, namely lethal reperfusion injury. - Ischemia-reperfusion injury has been the subject of intense research over the - last 40 years and our appreciation of the mechanisms of cellular death and - salvage have increased immensely over this time, to the extent that a number of - clearly identifiable therapeutic targets can now be subjected to clinical trials, - as the basic science translates into potentially effective therapies in patients - presenting with acute coronary syndromes. In this review, we aim to provide an - overview of current evidence regarding the mechanisms of lethal reperfusion - injury and endogenous protection, how cardioprotective pharmacological - manipulations have been approached to date, and to indicate where therapies may - be targeted in the future. -CI - © 2010 Blackwell Publishing Ltd. -FAU - Bell, Robert M -AU - Bell RM -AD - Hatter Institute for Cardiovascular Studies, Chenies Mews, London, UK. -FAU - Yellon, Derek M -AU - Yellon DM -LA - eng -PT - Journal Article -PT - Review -DEP - 20100714 -PL - England -TA - Cardiovasc Ther -JT - Cardiovascular therapeutics -JID - 101319630 -SB - IM -MH - Animals -MH - Cell Death -MH - Humans -MH - *Ischemic Postconditioning -MH - *Ischemic Preconditioning, Myocardial -MH - Myocardial Ischemia/metabolism/mortality/pathology/*therapy -MH - Myocardial Reperfusion Injury/etiology/metabolism/mortality/pathology/*prevention - & control -MH - Myocardial Revascularization/*adverse effects/mortality -MH - Myocardium/metabolism/pathology -MH - Treatment Outcome -EDAT- 2010/07/22 06:00 -MHDA- 2012/03/27 06:00 -CRDT- 2010/07/22 06:00 -PHST- 2010/07/22 06:00 [entrez] -PHST- 2010/07/22 06:00 [pubmed] -PHST- 2012/03/27 06:00 [medline] -AID - CDR190 [pii] -AID - 10.1111/j.1755-5922.2010.00190.x [doi] -PST - ppublish -SO - Cardiovasc Ther. 2011 Dec;29(6):e67-79. doi: 10.1111/j.1755-5922.2010.00190.x. - Epub 2010 Jul 14. - -PMID- 22825893 -OWN - NLM -STAT- MEDLINE -DCOM- 20121203 -LR - 20220330 -IS - 1898-018X (Electronic) -IS - 1898-018X (Linking) -VI - 19 -IP - 4 -DP - 2012 -TI - "Benign" early repolarization versus malignant early abnormalities: - clinical-electrocardiographic distinction and genetic basis. -PG - 337-46 -AB - In the great majority of cases the ECG pattern of early repolarization (ERP) is a - benign phenomenon observed predominantly in teenagers, young adults, male - athletes and the black race. The universally accepted criterion for its diagnosis - is the presence, in at least two adjoining leads, of ≥ 1 mm or 0.1 mV ST segment - elevation. In benign ERP reciprocal ST segment changes are possible only in lead - aVR. In contrast, reciprocal ST segment changes can be observed in several leads - in idiopathic ventricular fibrillation (IVF) and acute coronary syndrome. In - benign ERP the ST segment and T wave patterns have a relative temporal stability. - IVF is an entity with low prevalence, possibly familiar, and characterized by the - occurrence of VF events in a young person. More frequently this occurs in male - subjects without structural heart disease and with otherwise with normal ECG even - using high right accessory leads and/or after ajmaline injection. Several - clinical entities cause ST segment elevation include asthenic habitus, acute - pericarditis, ST segment elevation myocardial infarction, Brugada syndrome, - congenital short QT syndrome, and idiopathic VF. In these circumstances clinical - and ECG data are most important for differential diagnosis. In IVF the - modifications could be dramatic and predominantly at night during vagotonic - predominance when J waves > 2 mm in amplitude. The ST/T abnormalities are - dynamic, inconstant, and reversed with isoproterenol. Convex upward J waves, with - horizontal/descending ST segments or "lambda-wave" ST shape are suggestive of IVF - with early repolarization abnormalities. Premature ventricular contractions with - very short coupling and "R on T" phenomenon are characteristics with two pattern: - When originate from right ventricular outflow tract left bundle branch block - morphology and from peripheral Purkinje network, left bundle branch block - pattern. The inherited-familial forms are not frequent in IVF; however mutations - were identified in the genes KCNJ8, DPP6, SCN5A, SCN3B, CACNA1C, CACNB2, and - CACNA2D1. The management of IVF has class I indication for ICD implantation. - Ablation therapy is considered additional to ICD implantation in those patients - with repetitive ventricular arrhythmia. Quinidine is a highly efficient drug that - prevents recurrence. -FAU - Pérez-Riera, Andrés Ricardo -AU - Pérez-Riera AR -AD - ABC Faculty of Medicine, ABC Foundation, Santo André, Sao Paulo, Brazil. - riera@uol.com.br -FAU - Abreu, Luiz Carlos de -AU - Abreu LC -FAU - Yanowitz, Frank -AU - Yanowitz F -FAU - Barros, Raimundo Barbosa -AU - Barros RB -FAU - Femenía, Francisco -AU - Femenía F -FAU - McIntyre, William F -AU - McIntyre WF -FAU - Baranchuk, Adrian -AU - Baranchuk A -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - Cardiol J -JT - Cardiology journal -JID - 101392712 -RN - Paroxysmal ventricular fibrillation -SB - IM -MH - Action Potentials -MH - Adult -MH - Arrhythmias, Cardiac/*diagnosis/genetics/physiopathology/therapy -MH - Diagnosis, Differential -MH - *Electrocardiography -MH - Female -MH - Genetic Predisposition to Disease -MH - Heart Conduction System/*physiopathology -MH - Humans -MH - Male -MH - Predictive Value of Tests -MH - Prognosis -MH - Risk Assessment -MH - Risk Factors -MH - Time Factors -MH - Ventricular Fibrillation/*diagnosis/genetics/physiopathology/therapy -MH - Young Adult -EDAT- 2012/07/25 06:00 -MHDA- 2012/12/10 06:00 -CRDT- 2012/07/25 06:00 -PHST- 2012/07/25 06:00 [entrez] -PHST- 2012/07/25 06:00 [pubmed] -PHST- 2012/12/10 06:00 [medline] -AID - 10.5603/cj.2012.0063 [doi] -PST - ppublish -SO - Cardiol J. 2012;19(4):337-46. doi: 10.5603/cj.2012.0063. - -PMID- 22724471 -OWN - NLM -STAT- MEDLINE -DCOM- 20140305 -LR - 20250529 -IS - 1875-6212 (Electronic) -IS - 1570-1611 (Linking) -VI - 11 -IP - 4 -DP - 2013 Jul -TI - Review of trans-atlantic cardiovascular best medical therapy guidelines - - recommendations for asymptomatic carotid atherosclerosis. -PG - 514-23 -AB - The annual rate of ipsilateral stroke associated with asymptomatic carotid - stenosis has fallen from 2-4% to <1% in the last 20 years due to improvements in - medical therapy. The fundamental benefits of this are relevant to whether - patients undergo revascularisation or not. We aimed to evaluate existing - international guidelines for the management of carotid stenosis, identifying - important similarities and differences. The websites of the American Heart - Association, Society for Vascular Surgery, European Society for Cardiology, - European Society for Vascular Surgery, British Cardiovascular Society and UK - Vascular Society were searched for guidelines relating to primary prevention for - asymptomatic atherosclerotic carotid disease in September 2011 and independently - reviewed by 2 authors. The following guidelines were identified and compared: The - Joint British Societies 2nd (JBS2) 2005 guideline, the 4th European Society for - Cardiology (ESC) 2007 guideline, the joint American Heart Association/Society for - Vascular Surgery (AHA/SVS) guideline 2011 and subsequent 2011 SVS update, the - American Heart Association (AHA) prevention of stroke guideline 2010, the AHA - secondary prevention for atherosclerotic coronary and vascular disease 2011 - update, and the European Society for Vascular Surgery (ESVS) Section A carotid - guideline. There was no UK guidance from its vascular society. Important - differences were evident in methods of risk assessment, treatment targets for - blood pressure and low density lipoprotein cholesterol, and the use of - anti-platelet agents. These differences are highlighted in 2 case scenarios. - There is now clear, evidence based guidance from British, European and US - cardiovascular bodies regarding optimal targets for risk factor modification. - These can be adopted as standard operating procedure for clinical practice and - the medical arms of carotid interventional trials. In the future imaging - biomarkers may help provide an understanding of the risk of an individual carotid - lesion to help guide therapy. -FAU - Davies, Kerry J -AU - Davies KJ -AD - Imperial College London, London, UK. a.h.davies@imperial.ac.uk -FAU - Thapar, Ankur -AU - Thapar A -FAU - Kasivisvanathan, Veeru -AU - Kasivisvanathan V -FAU - Shalhoub, Joseph -AU - Shalhoub J -FAU - Davies, Alun H -AU - Davies AH -LA - eng -GR - RCS/DMT 3RD ROUND (3)/DMT_/The Dunhill Medical Trust/United Kingdom -PT - Comparative Study -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Vasc Pharmacol -JT - Current vascular pharmacology -JID - 101157208 -SB - IM -MH - Carotid Artery Diseases/complications/*therapy -MH - Carotid Stenosis/complications/*therapy -MH - Evidence-Based Medicine -MH - Humans -MH - Internationality -MH - *Practice Guidelines as Topic -MH - Risk Assessment/methods -MH - Risk Factors -MH - Societies, Medical -MH - Stroke/epidemiology/etiology/prevention & control -EDAT- 2012/06/26 06:00 -MHDA- 2014/03/07 06:00 -CRDT- 2012/06/26 06:00 -PHST- 2012/04/08 00:00 [received] -PHST- 2012/04/19 00:00 [revised] -PHST- 2012/04/24 00:00 [accepted] -PHST- 2012/06/26 06:00 [entrez] -PHST- 2012/06/26 06:00 [pubmed] -PHST- 2014/03/07 06:00 [medline] -AID - CVP-EPUB-20120622-11 [pii] -AID - 10.2174/1570161111311040015 [doi] -PST - ppublish -SO - Curr Vasc Pharmacol. 2013 Jul;11(4):514-23. doi: 10.2174/1570161111311040015. - -PMID- 23764371 -OWN - NLM -STAT- MEDLINE -DCOM- 20140407 -LR - 20220409 -IS - 1879-016X (Electronic) -IS - 0163-7258 (Linking) -VI - 140 -IP - 1 -DP - 2013 Oct -TI - Cardiovascular adenosine receptors: expression, actions and interactions. -PG - 92-111 -LID - S0163-7258(13)00128-9 [pii] -LID - 10.1016/j.pharmthera.2013.06.002 [doi] -AB - Intra- and extracellular adenosine levels rise in response to physiological - stimuli and with metabolic/energetic perturbations, inflammatory challenge and - tissue injury. Extracellular adenosine engages members of the G-protein coupled - adenosine receptor (AR) family to mediate generally beneficial acute and adaptive - responses within all constituent cells of the heart. In this way the four AR - sub-types-A1, A2A, A2B, and A3Rs-regulate myocardial contraction, heart rate and - conduction, adrenergic control, coronary vascular tone, cardiac and vascular - growth, inflammatory-vascular cell interactions, and cellular stress-resistance, - injury and death. The AR sub-types exert both distinct and overlapping effects, - and may interact in mediating these cardiovascular responses. The roles of the - ARs in beneficial modulation of cardiac and vascular function, growth and - stress-resistance render them attractive therapeutic targets. However, - interactions between ARs and with other receptors, and their ubiquitous - distribution throughout the body, can pose a challenge to the implementation of - site- and target-specific AR based pharmacotherapy. This review outlines - cardiovascular control by adenosine and the AR family in health and disease, - including interactions between AR sub-types within the heart and vessels. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Headrick, John P -AU - Headrick JP -AD - Heart Foundation Research Centre, Griffith Health Institute, Griffith University, - Southport, QLD, Australia. Electronic address: j.headrick@griffith.edu.au. -FAU - Ashton, Kevin J -AU - Ashton KJ -FAU - Rose'meyer, Roselyn B -AU - Rose'meyer RB -FAU - Peart, Jason N -AU - Peart JN -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130610 -PL - England -TA - Pharmacol Ther -JT - Pharmacology & therapeutics -JID - 7905840 -RN - 0 (Receptors, Purinergic P1) -RN - K72T3FS567 (Adenosine) -SB - IM -MH - Adenosine/physiology -MH - Animals -MH - Cardiovascular Diseases/metabolism/physiopathology -MH - Heart/*physiology -MH - Humans -MH - Receptors, Purinergic P1/*physiology -OTO - NOTNLM -OT - ADP -OT - AMP -OT - ANP -OT - AR -OT - ATP -OT - ATP-gated K(+) channel -OT - AV -OT - Adenosine receptors -OT - Angiogenesis -OT - CRE -OT - Cardioprotection -OT - Contractility -OT - ECM -OT - G-protein coupled receptor -OT - GPCR -OT - HIF -OT - Heart rate -OT - IFN -OT - IL- -OT - IMP -OT - K(ATP) -OT - MMP -OT - NO -OT - P(i) -OT - PI3K -OT - PKC -OT - PostCon -OT - PreCon -OT - Remodeling -OT - SA -OT - TNFα -OT - UTR -OT - VEGF -OT - adenosine diphosphate -OT - adenosine monophosphate -OT - adenosine receptor -OT - adenosine triphosphate -OT - atrial natriuretic peptide -OT - atrioventricular -OT - cAMP response element -OT - extracellular matrix -OT - hypoxia inducible factor -OT - inorganic phosphate -OT - inosine monophosphate -OT - interferon -OT - interleukin -OT - matrix metalloproteinase -OT - nitric oxide -OT - phosphoinositide 3-kinase -OT - postconditioning -OT - preconditioning -OT - protein kinase C -OT - sinoatrial -OT - tumor necrosis factor α -OT - untranslated region -OT - vascular endothelial growth factor -EDAT- 2013/06/15 06:00 -MHDA- 2014/04/08 06:00 -CRDT- 2013/06/15 06:00 -PHST- 2013/05/28 00:00 [received] -PHST- 2013/05/28 00:00 [accepted] -PHST- 2013/06/15 06:00 [entrez] -PHST- 2013/06/15 06:00 [pubmed] -PHST- 2014/04/08 06:00 [medline] -AID - S0163-7258(13)00128-9 [pii] -AID - 10.1016/j.pharmthera.2013.06.002 [doi] -PST - ppublish -SO - Pharmacol Ther. 2013 Oct;140(1):92-111. doi: 10.1016/j.pharmthera.2013.06.002. - Epub 2013 Jun 10. - -PMID- 20495512 -OWN - NLM -STAT- MEDLINE -DCOM- 20100708 -LR - 20220325 -IS - 1530-6550 (Print) -IS - 1530-6550 (Linking) -VI - 11 -IP - 1 -DP - 2010 Winter -TI - Heparin-induced thrombocytopenia: a practical review. -PG - 13-25 -LID - 10.3909/ricm0495 [doi] -AB - Heparin-induced thrombocytopenia (HIT) remains under-recognized despite its - potentially devastating outcomes. It begins when heparin exposure stimulates the - formation of heparin-platelet factor 4 antibodies, which in turn triggers the - release of procoagulant platelet particles. Thrombosis and thrombocytopenia that - follow comprise the 2 hallmark traits of HIT, with the former largely responsible - for significant vascular complications. The prevalence of HIT varies among - several subgroups, with greater incidence in surgical as compared with medical - populations. HIT must be acknowledged for its intense predilection for thrombosis - and suspected whenever thrombosis occurs after heparin exposure. Early - recognition that incorporates the clinical and serologic clues is paramount to - timely institution of treatment, as its delay may result in catastrophic - outcomes. The treatment of HIT mandates an immediate cessation of all heparin - exposure and the institution of an antithrombotic therapy, most commonly using a - direct thrombin inhibitor. Current "diagnostic" tests, which primarily include - functional and antigenic assays, have more of a confirmatory than diagnostic role - in the management of HIT. Special attention must be paid to cardiac patients who - are often exposed to heparin multiple times during their course of treatment. - Direct thrombin inhibitors are appropriate, evidence-based alternatives to - heparin in patients with a history of HIT, who need to undergo percutaneous - coronary intervention. As heparin remains one of the most frequently used - medications today with potential for HIT with every heparin exposure, a close - vigilance of platelet counts must be practiced whenever heparin is initiated. -FAU - Hong, Michael S -AU - Hong MS -AD - Division of Cardiovascular Disease, Department of Medicine, Albert Einstein - Medical Center, Philadelphia, PA, USA. -FAU - Amanullah, Aman M -AU - Amanullah AM -LA - eng -PT - Journal Article -PT - Review -PL - Singapore -TA - Rev Cardiovasc Med -JT - Reviews in cardiovascular medicine -JID - 100960007 -RN - 0 (Anticoagulants) -RN - 0 (Antithrombins) -RN - 0 (Hirudins) -RN - 0 (Peptide Fragments) -RN - 0 (Recombinant Proteins) -RN - 9005-49-6 (Heparin) -RN - TN9BEX005G (bivalirudin) -SB - IM -MH - Anticoagulants/*adverse effects -MH - Antithrombins/therapeutic use -MH - Cardiac Surgical Procedures -MH - Heart Diseases/epidemiology/surgery -MH - Heparin/*adverse effects -MH - Hirudins -MH - Humans -MH - Immunoassay -MH - Monitoring, Physiologic/standards -MH - Peptide Fragments/therapeutic use -MH - Practice Guidelines as Topic -MH - Recombinant Proteins/therapeutic use -MH - Risk Factors -MH - Thrombocytopenia/*chemically induced/diagnosis/drug - therapy/epidemiology/etiology/prevention & control -RF - 45 -EDAT- 2010/05/25 06:00 -MHDA- 2010/07/09 06:00 -CRDT- 2010/05/25 06:00 -PHST- 2010/05/25 06:00 [entrez] -PHST- 2010/05/25 06:00 [pubmed] -PHST- 2010/07/09 06:00 [medline] -AID - 10.3909/ricm0495 [doi] -PST - ppublish -SO - Rev Cardiovasc Med. 2010 Winter;11(1):13-25. doi: 10.3909/ricm0495. - -PMID- 28496756 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20201001 -IS - 1941-6911 (Print) -IS - 1941-6911 (Electronic) -IS - 1941-6911 (Linking) -VI - 5 -IP - 2 -DP - 2012 Aug-Sep -TI - Effect of Omega-3 Polyunsaturated Fatty Acid Supplementation in Patients with - Atrial Fibrillation. -PG - 502 -LID - 10.4022/jafib.502 [doi] -LID - 502 -AB - Atrial fibrillation (AF) is the most common sustained atrial arrhythmia - conferring a higher morbidity and mortality. Despite the increasing incidence of - AF; available therapies are far from perfect. Dietary fish oils, containing omega - 3 fatty acids, also called polyunsaturated fatty acid [PUFA] have demonstrated - beneficial electrophysiological, autonomic and anti-inflammatory effects on both - atrial and ventricular tissue. Multiple clinical trials, focusing on various - subsets of patients with AF, have studied the role of PUFA and their potential - role in reducing the incidence of this common arrhythmia. While PUFA appears to - have a beneficial effect in the primary prevention of AF in the elderly with - structural heart disease, this benefit has not been universally observed. In the - secondary prevention of AF, PUFA seems to have a greater impact in the reducing - AF in patients with paroxysmal or persistent AF, stages of AF associated with - less atrial fibrosis and negative structural remodeling. However, AF suppression - has not been consistently demonstrated in clinical trials. In patients undergoing - heart surgery, increasing PUFA intake has yielded mixed results in terms of AF - prevention post-operatively; however, increased PUFA has been associated with a - reduction in hospital stay. Therefore recommending the use of PUFA for the - purpose of AF reduction remains controversial. This is in part attributable to - the complexity of AF. Other conflicting variables include: heterogeneous patient - populations studied; variable dosing; duration of follow-up; comorbidities; and, - concomitant pharmacotherapy. This review article reviews in detail available - basic and clinical research studies of fish oil in the treatment of AF, and its - role in the treatment of this common disorder. ABBREVIATIONS: AF=Atrial - fibrillation, CHS=Cardiovascular Health Study,CABG=Coronary artery bypass - surgery, d=Day, DHA=Docosahexaenoic acid, EPA=Eicosapentaenoic acid, ERP= - Effective refractory period, g=Gram, PAF= Paroxysmal atrial fibrillation, PeAF= - Persistent atrial fibrillation PUFA= Polyunsaturated fatty acid. -FAU - Kumar, Sanjay -AU - Kumar S -AD - Department of Cardiovascular Diseases, SUNY Downstate Medical Center, 450 - Clarkson Avenue, Box 1199 Brooklyn, NY 11203. -FAU - Qu, Sarah -AU - Qu S -AD - Department of Cardiovascular Diseases, SUNY Downstate Medical Center, 450 - Clarkson Avenue, Box 1199 Brooklyn, NY 11203. -FAU - Kassotis, John T -AU - Kassotis JT -AD - Department of Cardiovascular Diseases, SUNY Downstate Medical Center, 450 - Clarkson Avenue, Box 1199 Brooklyn, NY 11203. -LA - eng -PT - Journal Article -PT - Review -DEP - 20120820 -PL - United States -TA - J Atr Fibrillation -JT - Journal of atrial fibrillation -JID - 101514767 -PMC - PMC5153119 -OTO - NOTNLM -OT - Atrial fibrillation -OT - Omega 3 fatty acid -OT - PUFA -EDAT- 2012/08/20 00:00 -MHDA- 2012/08/20 00:01 -PMCR- 2012/08/20 -CRDT- 2017/05/13 06:00 -PHST- 2011/12/15 00:00 [received] -PHST- 2012/05/11 00:00 [revised] -PHST- 2012/06/21 00:00 [accepted] -PHST- 2017/05/13 06:00 [entrez] -PHST- 2012/08/20 00:00 [pubmed] -PHST- 2012/08/20 00:01 [medline] -PHST- 2012/08/20 00:00 [pmc-release] -AID - 10.4022/jafib.502 [doi] -PST - epublish -SO - J Atr Fibrillation. 2012 Aug 20;5(2):502. doi: 10.4022/jafib.502. eCollection - 2012 Aug-Sep. - -PMID- 17881625 -OWN - NLM -STAT- MEDLINE -DCOM- 20071127 -LR - 20250623 -IS - 1077-5587 (Print) -IS - 1077-5587 (Linking) -VI - 64 -IP - 5 Suppl -DP - 2007 Oct -TI - Cardiovascular health disparities: a systematic review of health care - interventions. -PG - 29S-100S -AB - Racial and ethnic disparities in cardiovascular health care are well documented. - Promising approaches to disparity reduction are increasingly described in - literature published since 1995, but reports are fragmented by risk, condition, - population, and setting. The authors conducted a systematic review of clinically - oriented studies in communities of color that addressed hypertension, - hyperlipidemia, physical inactivity, tobacco, and two major cardiovascular - conditions, coronary artery disease and heart failure. Virtually no literature - specifically addressed disparity reduction. The greatest focus has been African - American populations, with relatively little work in Hispanic, Asian, and Native - American populations. The authors found 62 interventions, 27 addressing - hypertension, 9 lipids, 18 tobacco use, 8 physical inactivity, and 7 heart - failure. Only 1 study specifically addressed postmyocardial infarction care. Data - supporting the value of registries, multidisciplinary teams, and community - outreach were found across several conditions. Interventions addressing care - transitions, using telephonic outreach, and promoting medication access and - adherence merit further exploration. -FAU - Davis, Andrew M -AU - Davis AM -AD - The University of Chicago, Chicago, IL 60637, USA. amd@uchicago.edu -FAU - Vinci, Lisa M -AU - Vinci LM -FAU - Okwuosa, Tochi M -AU - Okwuosa TM -FAU - Chase, Ayana R -AU - Chase AR -FAU - Huang, Elbert S -AU - Huang ES -LA - eng -GR - K23 AG021963/AG/NIA NIH HHS/United States -GR - P60 DK020595/DK/NIDDK NIH HHS/United States -GR - P60 DK20595/DK/NIDDK NIH HHS/United States -GR - T35 DK062419-20/DK/NIDDK NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - United States -TA - Med Care Res Rev -JT - Medical care research and review : MCRR -JID - 9506850 -SB - IM -MH - Cardiovascular Diseases/prevention & control/*therapy -MH - Ethnicity -MH - *Healthcare Disparities -MH - Humans -MH - Minority Groups -MH - Outcome Assessment, Health Care -MH - Quality Assurance, Health Care -MH - Quality of Health Care -MH - United States -PMC - PMC2367222 -MID - NIHMS44292 -EDAT- 2007/10/19 09:00 -MHDA- 2007/12/06 09:00 -PMCR- 2008/05/05 -CRDT- 2007/10/19 09:00 -PHST- 2007/10/19 09:00 [pubmed] -PHST- 2007/12/06 09:00 [medline] -PHST- 2007/10/19 09:00 [entrez] -PHST- 2008/05/05 00:00 [pmc-release] -AID - 64/5S/29S [pii] -AID - 10.1177/1077558707305416 [doi] -PST - ppublish -SO - Med Care Res Rev. 2007 Oct;64(5 Suppl):29S-100S. doi: 10.1177/1077558707305416. - -PMID- 17002798 -OWN - NLM -STAT- MEDLINE -DCOM- 20061114 -LR - 20181113 -IS - 1475-2840 (Electronic) -IS - 1475-2840 (Linking) -VI - 5 -DP - 2006 Sep 26 -TI - Atherogenic dyslipidemia in metabolic syndrome and type 2 diabetes: therapeutic - options beyond statins. -PG - 20 -AB - Lowering of low-density lipoprotein cholesterol with 3-hydroxy-3-methylglutaryl - coenzyme A reductase inhibitors (statins) is clearly efficacious in the treatment - and prevention of coronary artery disease. However, despite increasing use of - statins, a significant number of coronary events still occur and many of such - events take place in patients presenting with type 2 diabetes and metabolic - syndrome. More and more attention is being paid now to combined atherogenic - dyslipidemia which typically presents in patients with type 2 diabetes and - metabolic syndrome. This mixed dyslipidemia (or "lipid quartet"): - hypertriglyceridemia, low high-density lipoprotein cholesterol levels, a - preponderance of small, dense low-density lipoprotein particles and an - accumulation of cholesterol-rich remnant particles (e.g. high levels of - apolipoprotein B)--emerged as the greatest "competitor" of low-density - lipoprotein-cholesterol among lipid risk factors for cardiovascular disease. Most - recent extensions of the fibrates trials (BIP - Bezafibrate Infarction Prevention - study, HHS - Helsinki Heart Study, VAHIT--Veterans Affairs High-density - lipoprotein cholesterol Intervention Trial and FIELD--Fenofibrate Intervention - and Event Lowering in Diabetes) give further support to the hypothesis that - patients with insulin-resistant syndromes such as diabetes and/or metabolic - syndrome might be the ones to derive the most benefit from therapy with fibrates. - However, different fibrates may have a somewhat different spectrum of effects. - Other lipid-modifying strategies included using of niacin, ezetimibe, bile acid - sequestrants and cholesteryl ester transfer protein inhibition. In addition, - bezafibrate as pan-peroxisome proliferator activated receptor activator has - clearly demonstrated beneficial pleiotropic effects related to glucose metabolism - and insulin sensitivity. Because fibrates, niacin, ezetimibe and statins each - regulate serum lipids by different mechanisms, combination therapy--selected on - the basis of their safety and effectiveness - may offer particularly desirable - benefits in patients with combined hyperlipidemia as compared with statins - monotherapy. -FAU - Tenenbaum, Alexander -AU - Tenenbaum A -AD - Cardiac Rehabilitation Institute, the Chaim Sheba Medical Center, 52621 - Tel-Hashomer, Israel. altenen@post.tau.ac.il -FAU - Fisman, Enrique Z -AU - Fisman EZ -FAU - Motro, Michael -AU - Motro M -FAU - Adler, Yehuda -AU - Adler Y -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20060926 -PL - England -TA - Cardiovasc Diabetol -JT - Cardiovascular diabetology -JID - 101147637 -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 2679MF687A (Niacin) -RN - 53PF01Q249 (Clofibric Acid) -SB - IM -MH - Clofibric Acid/therapeutic use -MH - Diabetes Mellitus, Type 2/blood/complications/*drug therapy -MH - Drug Therapy, Combination -MH - Dyslipidemias/blood/complications/*drug therapy -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Metabolic Syndrome/blood/complications/*drug therapy -MH - Niacin/therapeutic use -PMC - PMC1592077 -EDAT- 2006/09/28 09:00 -MHDA- 2006/11/15 09:00 -PMCR- 2006/09/26 -CRDT- 2006/09/28 09:00 -PHST- 2006/09/23 00:00 [received] -PHST- 2006/09/26 00:00 [accepted] -PHST- 2006/09/28 09:00 [pubmed] -PHST- 2006/11/15 09:00 [medline] -PHST- 2006/09/28 09:00 [entrez] -PHST- 2006/09/26 00:00 [pmc-release] -AID - 1475-2840-5-20 [pii] -AID - 10.1186/1475-2840-5-20 [doi] -PST - epublish -SO - Cardiovasc Diabetol. 2006 Sep 26;5:20. doi: 10.1186/1475-2840-5-20. - -PMID- 20205050 -OWN - NLM -STAT- MEDLINE -DCOM- 20100604 -LR - 20131121 -IS - 2040-3437 (Electronic) -IS - 1367-6733 (Linking) -VI - 13 -IP - 2 -DP - 2010 Mar -TI - Molecular basis of different outcomes for drug-eluting stents that release - sirolimus or tacrolimus. -PG - 159-68 -AB - Sirolimus and tacrolimus are potent immunosuppressants that are delivered by - drug-eluting stents (DES) for the prevention of in-stent restenosis. Balloon - angioplasty with stent implantation has emerged as a successful treatment for - coronary stenoses; angioplasty dilates the vessel lumen and the stent prevents - elastic recoil of the vessel walls. However, angioplasty and stent placement both - produce vascular injuries that potently stimulate the proliferation of smooth - muscle cells, resulting in a thickening of the vascular wall. The purpose of DES - is to deliver pharmacological agents that counteract neointimal hyperplasia. The - sirolimus-eluting-stent reduces the incidence of in-stent restenosis - significantly, whereas the tacrolimus-eluting-stent demonstrates no improvement - in clinical benefit compared with a bare stent. Although sirolimus and tacrolimus - have similar molecular structures, these drugs regulate immune activation via - different mechanisms of action. The effects of this class of drugs are mediated - by binding to the FK-506-binding proteins (FKBPs), which are highly - evolutionarily conserved across species. This review highlights the structure and - function of sirolimus, tacrolimus and FKBPs, with particular focus on recent - observations that the two drugs target signaling pathways involved in the control - of vascular smooth muscle apoptosis and proliferation directly. -FAU - Giordano, Arturo -AU - Giordano A -AD - Pineta Grande Clinic, Invasive Cardiology Unit, via Domiziana km30, - Castelvolturno 81030, Italy. arturogiordano@tin.it -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Curr Opin Drug Discov Devel -JT - Current opinion in drug discovery & development -JID - 100887519 -RN - 0 (Immunosuppressive Agents) -RN - EC 5.2.1.- (Tacrolimus Binding Proteins) -RN - W36ZG6FT64 (Sirolimus) -RN - WM0HAQ4WNM (Tacrolimus) -SB - IM -MH - Animals -MH - Cell Proliferation/drug effects -MH - Coronary Restenosis/*prevention & control -MH - Drug Delivery Systems -MH - *Drug-Eluting Stents -MH - Humans -MH - Immunosuppressive Agents/*administration & dosage -MH - Models, Biological -MH - Muscle, Smooth, Vascular/drug effects -MH - Protein Binding/drug effects -MH - Signal Transduction/drug effects -MH - Sirolimus/*administration & dosage/chemistry/pharmacology -MH - Tacrolimus/*administration & dosage/chemistry/pharmacology -MH - Tacrolimus Binding Proteins/metabolism -RF - 100 -EDAT- 2010/03/06 06:00 -MHDA- 2010/06/05 06:00 -CRDT- 2010/03/06 06:00 -PHST- 2010/03/06 06:00 [entrez] -PHST- 2010/03/06 06:00 [pubmed] -PHST- 2010/06/05 06:00 [medline] -PST - ppublish -SO - Curr Opin Drug Discov Devel. 2010 Mar;13(2):159-68. - -PMID- 17662400 -OWN - NLM -STAT- MEDLINE -DCOM- 20070822 -LR - 20191210 -IS - 1558-3597 (Electronic) -IS - 0735-1097 (Linking) -VI - 50 -IP - 5 -DP - 2007 Jul 31 -TI - Stent thrombosis, myocardial infarction, and death after drug-eluting and - bare-metal stent coronary interventions. -PG - 463-70 -AB - OBJECTIVES: The aim of the study was to examine outcomes subsequent to - implantation of drug-eluting stents (DES) and bare-metal stents (BMS). - BACKGROUND: Use of DES might be associated with increased risk of stent - thrombosis (ST), myocardial infarction (MI), and death. METHODS: From January - 2002 through June 2005, data from all percutaneous coronary interventions in - western Denmark were prospectively recorded in the Western Denmark Heart - Registry; 12,395 consecutive patients (17,152 lesions) treated with stent - implantation were followed for 15 months. Data on death and MI were ascertained - from the national databases. The Academic Research Consortium definition of ST - was used. RESULTS: The DES were implanted in 3,548 patients (5,422 lesions) and - BMS were implanted in 8,847 patients (11,730 lesions). Definite, probable, or - possible ST was found in 190 (2.15%) patients in the BMS group and in 64 (1.80%) - patients in the DES. The risk of definite ST was similar in the 2 groups (DES: - 0.65%; BMS: 0.61%). Very late definite ST (between 12 and 15 months after - implantation) occurred more frequently in patients receiving DES (hazard ratio - [HR] 10.93, 95% confidence interval [CI] 1.27 to 93.76). Also, the risk of MI - between 12 and 15 months after implantation was higher in the DES group (HR 4.00, - 95% CI 2.06 to 7.79). Mortality was similar in the 2 groups. Target lesion - revascularization was reduced by 43% in patients treated with DES (HR 0.57, 95% - CI 0.48 to 0.67). CONCLUSIONS: The minor risk of ST and MI within 15 months after - implantation of DES seems unlikely to outweigh the benefit of these stents. -FAU - Jensen, Lisette Okkels -AU - Jensen LO -AD - Department of Cardiology, Odense University Hospital, Odense, Denmark. - okkels@dadlnet.dk -FAU - Maeng, Michael -AU - Maeng M -FAU - Kaltoft, Anne -AU - Kaltoft A -FAU - Thayssen, Per -AU - Thayssen P -FAU - Hansen, Hans Henrik Tilsted -AU - Hansen HH -FAU - Bottcher, Morten -AU - Bottcher M -FAU - Lassen, Jens Flensted -AU - Lassen JF -FAU - Krussel, Lars Romer -AU - Krussel LR -FAU - Rasmussen, Klaus -AU - Rasmussen K -FAU - Hansen, Knud Noerregaard -AU - Hansen KN -FAU - Pedersen, Lars -AU - Pedersen L -FAU - Johnsen, Soeren Paaske -AU - Johnsen SP -FAU - Soerensen, Henrik Toft -AU - Soerensen HT -FAU - Thuesen, Leif -AU - Thuesen L -LA - eng -PT - Comparative Study -PT - Journal Article -PT - Review -DEP - 20070629 -PL - United States -TA - J Am Coll Cardiol -JT - Journal of the American College of Cardiology -JID - 8301365 -SB - IM -CIN - J Am Coll Cardiol. 2008 Mar 4;51(9):972; author reply 972-3. doi: - 10.1016/j.jacc.2007.08.070. PMID: 18308171 -MH - Aged -MH - Causality -MH - Cause of Death -MH - Comorbidity -MH - Coronary Thrombosis/*epidemiology -MH - Denmark/epidemiology -MH - Drug Delivery Systems/adverse effects/statistics & numerical data -MH - Female -MH - Follow-Up Studies -MH - Humans -MH - Incidence -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/*epidemiology -MH - Outcome and Process Assessment, Health Care -MH - Prospective Studies -MH - Registries -MH - Risk Assessment -MH - Stents/*adverse effects/*statistics & numerical data -RF - 26 -EDAT- 2007/07/31 09:00 -MHDA- 2007/08/23 09:00 -CRDT- 2007/07/31 09:00 -PHST- 2007/04/04 00:00 [received] -PHST- 2007/05/21 00:00 [revised] -PHST- 2007/06/03 00:00 [accepted] -PHST- 2007/07/31 09:00 [pubmed] -PHST- 2007/08/23 09:00 [medline] -PHST- 2007/07/31 09:00 [entrez] -AID - S0735-1097(07)01784-6 [pii] -AID - 10.1016/j.jacc.2007.06.002 [doi] -PST - ppublish -SO - J Am Coll Cardiol. 2007 Jul 31;50(5):463-70. doi: 10.1016/j.jacc.2007.06.002. - Epub 2007 Jun 29. - -PMID- 16484628 -OWN - NLM -STAT- MEDLINE -DCOM- 20071031 -LR - 20220316 -IS - 1524-4571 (Electronic) -IS - 0009-7330 (Linking) -VI - 98 -IP - 3 -DP - 2006 Feb 17 -TI - Rho kinases in cardiovascular physiology and pathophysiology. -PG - 322-34 -AB - Rho kinases (ROCKs) are the first and the best-characterized effectors of the - small G-protein RhoA. In addition to their effect on actin organization, or - through this effect, ROCKs have been found to regulate a wide range of - fundamental cell functions such as contraction, motility, proliferation, and - apoptosis. Abnormal activation of the RhoA/ROCK pathway has been observed in - major cardiovascular disorders such as atherosclerosis, restenosis, hypertension, - pulmonary hypertension, and cardiac hypertrophy. This review, based on recent - molecular, cellular, and animal studies, focuses on the current understanding of - ROCK signaling and its roles in cardiovascular physiology and pathophysiology. -FAU - Loirand, Gervaise -AU - Loirand G -AD - INSERM U-533-Institut du Thorax, Faculté des Sciences, Nantes, France. -FAU - Guérin, Patrice -AU - Guérin P -FAU - Pacaud, Pierre -AU - Pacaud P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - Circ Res -JT - Circulation research -JID - 0047103 -RN - 0 (Intracellular Signaling Peptides and Proteins) -RN - EC 2.7.11.1 (Protein Serine-Threonine Kinases) -RN - EC 2.7.11.1 (rho-Associated Kinases) -SB - IM -MH - Atherosclerosis/enzymology/physiopathology -MH - Cardiovascular Diseases/enzymology/*physiopathology -MH - *Cardiovascular Physiological Phenomena -MH - Cardiovascular System/*physiopathology -MH - Coronary Restenosis -MH - Endothelium, Vascular/physiology -MH - Humans -MH - Hypertension/enzymology/physiopathology -MH - Inflammation/enzymology/physiopathology -MH - Intracellular Signaling Peptides and Proteins/*metabolism -MH - Muscle, Smooth, Vascular/physiology -MH - Protein Serine-Threonine Kinases/*metabolism -MH - rho-Associated Kinases -RF - 127 -EDAT- 2006/02/18 09:00 -MHDA- 2007/11/01 09:00 -CRDT- 2006/02/18 09:00 -PHST- 2006/02/18 09:00 [pubmed] -PHST- 2007/11/01 09:00 [medline] -PHST- 2006/02/18 09:00 [entrez] -AID - 98/3/322 [pii] -AID - 10.1161/01.RES.0000201960.04223.3c [doi] -PST - ppublish -SO - Circ Res. 2006 Feb 17;98(3):322-34. doi: 10.1161/01.RES.0000201960.04223.3c. - -PMID- 17877207 -OWN - NLM -STAT- MEDLINE -DCOM- 20071113 -LR - 20080212 -IS - 0040-5930 (Print) -IS - 0040-5930 (Linking) -VI - 64 -IP - 6 -DP - 2007 Jun -TI - [Implications of gender-specific aspects in the therapy of cardiovascular - diseases]. -PG - 311-7 -AB - In cardiovascular diseases e.g. heart failure and coronary artery disease gender - differences are evident in etiology, pathophysiology, clinical presentation, - prognosis and response to treatment. Diabetes and hypertension are the major risk - factors in women. Mechanisms leading to apparent diabetes or its clinical - pre-stage are different in women and men and according to this result in - different therapeutic implications. Diastolic heart failure is more frequent in - women and effects and side effects of important groups of active pharmaceutical - substances are, at least to some extent, different. Atrial fibrillation and - ventricular arrhythmia differ in frequency of occurrence; drug induced - tachycardia with QT interval prolongation is particularly frequent in women. - Underlying pathomechanisms responsible for gender differences in pharmacotherapy - are on the one hand differences in pharmacokinetic mechanisms. Particularly drugs - which are metabolised via cytochrome P 450 CYP 3A pathway show different kinetics - in women and men. In addition, important differences are evident in - pharmocodynamics caused by effects of sex steroid hormones or products of - X-chromosomal genes. The evidence of estrogen and testosterone receptors in - cardiomyocytes and the vascular system, interaction of sex steroid hormones with - cellular pathways and the role of X-chromosomal genes are the focus of basic - research. Interactions of sex steroid hormone receptors with other nuclear - receptors e.g. PPARs ("peroxisome proliferator-activated receptors") are another - important underlying mechanism. The knowledge of different pharmacokinetic - mechanisms has to be taken into consideration in pharmacotherapy of - cardiovascular diseases, for example by adjustment of drug dosages in women, - necessary in different groups of pharmaceutical substances or in the long run, - gender differences in effects and side effects of drugs. In drug development both - aspects have to be considered. There is more than one good reason to intensify - basic and clinical research and research on health care on gender differences in - cardiovascular diseases. -FAU - Lehmkuhl, E -AU - Lehmkuhl E -AD - Herz-Kreislauferkrankungen bei Frauen, Geschlechterforschung in der Medizin/GIM, - Deutsches Herzzentrum Berlin und Charité/CCR, Berlin. -FAU - Regitz-Zagrosek, V -AU - Regitz-Zagrosek V -LA - ger -PT - English Abstract -PT - Journal Article -PT - Review -TT - Therapeutische Implika- tionen gender-spezifischer Aspekte von Herzkrankheiten. -PL - Switzerland -TA - Ther Umsch -JT - Therapeutische Umschau. Revue therapeutique -JID - 0407224 -SB - IM -MH - Cardiovascular Diseases/*mortality/*therapy -MH - Female -MH - Humans -MH - Male -MH - Prevalence -MH - Risk Assessment/*methods -MH - Risk Factors -MH - Sex Distribution -MH - Sex Factors -RF - 30 -EDAT- 2007/09/20 09:00 -MHDA- 2007/11/14 09:00 -CRDT- 2007/09/20 09:00 -PHST- 2007/09/20 09:00 [pubmed] -PHST- 2007/11/14 09:00 [medline] -PHST- 2007/09/20 09:00 [entrez] -AID - 10.1024/0040-5930.64.6.311 [doi] -PST - ppublish -SO - Ther Umsch. 2007 Jun;64(6):311-7. doi: 10.1024/0040-5930.64.6.311. - -PMID- 17159076 -OWN - NLM -STAT- MEDLINE -DCOM- 20070103 -LR - 20220409 -IS - 1524-4539 (Electronic) -IS - 0009-7322 (Linking) -VI - 114 -IP - 24 -DP - 2006 Dec 12 -TI - Transposition of the great arteries. -PG - 2699-709 -AB - Many patients with ventriculoarterial discordance have survived to adulthood. - Those with complete transposition of the great arteries have often had an atrial - switch procedure (Mustard or Senning operation) performed, which leaves the - morphological right ventricle (RV) supporting the systemic circulation. RV - failure and tricuspid regurgitation are common. Some patients may ultimately - require cardiac transplantation. Sinus node dysfunction is increasingly common - with longer follow-up, and some patients need pacemaker implantation. Atrial - arrhythmias are frequent, and atrial flutter may be a marker for sudden death. - Patients with an arterial switch procedure are also surviving to adulthood. - Long-term problems include coronary stenoses, distortion of the pulmonary - arteries, dilatation of the neoaortic root, and aortic regurgitation. Patients - with congenitally corrected transposition have both atrioventricular and - ventriculoarterial discordance and therefore also have a morphological RV and - delicate tricuspid valve in the systemic circulation. Associated defects, such as - abnormalities of the tricuspid valve, ventricular septal defect, and pulmonary - stenosis, occur in the majority of patients. Heart block occurs with increasing - age. Atrial arrhythmias occur frequently, and their occurrence should prompt a - search for a hemodynamic problem. Progressive tricuspid regurgitation occurs with - age and is associated with deterioration of RV function. Surgical treatment - should be considered at the earliest sign of RV dilatation or dysfunction. All - patients should be seen periodically in a center where expertise in the clinical - evaluation, imaging, and hemodynamic assessment of adult congenital heart disease - is available. -FAU - Warnes, Carole A -AU - Warnes CA -AD - Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo - Clinic, 200 First St SW, Rochester, MN 55905, USA. warnes.carole@mayo.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Circulation -JT - Circulation -JID - 0147763 -SB - IM -MH - Arrhythmias, Cardiac/etiology -MH - Cardiac Catheterization -MH - Echocardiography -MH - Electrocardiography -MH - Follow-Up Studies -MH - Humans -MH - Hypertension, Pulmonary/etiology -MH - Magnetic Resonance Imaging -MH - Transposition of Great Vessels/complications/diagnosis/pathology/*surgery -MH - Tricuspid Valve Insufficiency/etiology -MH - Ventricular Dysfunction/etiology -RF - 78 -EDAT- 2006/12/13 09:00 -MHDA- 2007/01/04 09:00 -CRDT- 2006/12/13 09:00 -PHST- 2006/12/13 09:00 [pubmed] -PHST- 2007/01/04 09:00 [medline] -PHST- 2006/12/13 09:00 [entrez] -AID - 114/24/2699 [pii] -AID - 10.1161/CIRCULATIONAHA.105.592352 [doi] -PST - ppublish -SO - Circulation. 2006 Dec 12;114(24):2699-709. doi: - 10.1161/CIRCULATIONAHA.105.592352. - -PMID- 23562124 -OWN - NLM -STAT- MEDLINE -DCOM- 20131205 -LR - 20220408 -IS - 1551-7136 (Print) -IS - 1551-7136 (Linking) -VI - 9 -IP - 2 -DP - 2013 Apr -TI - Chemotherapy-induced takotsubo cardiomyopathy. -PG - 233-42, x -LID - S1551-7136(12)00122-5 [pii] -LID - 10.1016/j.hfc.2012.12.009 [doi] -AB - Stress cardiomyopathy, also known as takotsubo cardiomyopathy, is a rapidly - reversible form of acute heart failure classically triggered by stressful events. - It is associated with a distinctive left ventricular contraction pattern - described as apical akinesis/ballooning with hyperdynamic contraction of the - basal segments in the absence of obstructive coronary artery disease. The - traditional paradigm has expanded to include other causes, in particular - chemotherapeutic drugs. The literature increasingly suggests an association - between cancer, chemotherapeutic drugs, and stress cardiomyopathy. - Chemotherapy-induced takotsubo cardiomyopathy is a relatively new phenomenon, but - one that merits detailed attention to the elucidation of possible mechanistic - links. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Smith, Sakima A -AU - Smith SA -AD - Division of Cardiovascular Medicine, Davis Heart & Lung Research Institute, The - Ohio State University Medical Center, Suite 200, 473 West 12th Avenue, Columbus, - OH 43210-1252, USA. sakima.smith@osumc.edu -FAU - Auseon, Alex J -AU - Auseon AJ -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20130123 -PL - United States -TA - Heart Fail Clin -JT - Heart failure clinics -JID - 101231934 -RN - 0 (Antibodies, Monoclonal, Murine-Derived) -RN - 0 (Antimetabolites, Antineoplastic) -RN - 0 (Antineoplastic Agents) -RN - 4F4X42SYQ6 (Rituximab) -RN - U3P01618RT (Fluorouracil) -SB - IM -MH - Antibodies, Monoclonal, Murine-Derived/*adverse effects/therapeutic use -MH - Antimetabolites, Antineoplastic/adverse effects -MH - Antineoplastic Agents/*adverse effects/therapeutic use -MH - Echocardiography -MH - Electrocardiography -MH - Female -MH - Fluorouracil/adverse effects -MH - Humans -MH - Lymphoma/*drug therapy -MH - Middle Aged -MH - Rituximab -MH - Stroke Volume/physiology -MH - Takotsubo Cardiomyopathy/*chemically induced/diagnosis/physiopathology -MH - Ventricular Dysfunction, Left/chemically induced/diagnosis/physiopathology -EDAT- 2013/04/09 06:00 -MHDA- 2013/12/16 06:00 -CRDT- 2013/04/09 06:00 -PHST- 2013/04/09 06:00 [entrez] -PHST- 2013/04/09 06:00 [pubmed] -PHST- 2013/12/16 06:00 [medline] -AID - S1551-7136(12)00122-5 [pii] -AID - 10.1016/j.hfc.2012.12.009 [doi] -PST - ppublish -SO - Heart Fail Clin. 2013 Apr;9(2):233-42, x. doi: 10.1016/j.hfc.2012.12.009. Epub - 2013 Jan 23. - -PMID- 19860685 -OWN - NLM -STAT- MEDLINE -DCOM- 20100105 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 15 -IP - 29 -DP - 2009 -TI - Pathophysiological insights into atrial fibrillation following cardiac surgery: - implications for current pharmaceutical design. -PG - 3367-83 -AB - Atrial fibrillation (AF) following cardiac surgery is a common complication, - which increases incidence of other complications, hospital and healthcare costs. - The reported rate of the occurrence of postoperative AF varies with different - studies, depending on population profile, type of surgery, arrhythmia definition - and detection methods, design of study. Nonetheless, the precise mechanisms of AF - related to cardiac surgery are poorly understood. A diverse variety of reasons - have been proposed for the pathogenesis of this common cardiac arrhythmia. The - aim of this review article is to provide an overview of pathophysiological - processes that lead to the development of AF post-cardiac surgery. These - processes are closely inter-related but the most important ones that have bearing - on drug design include the RAAS, ion channels, connexins, fibrosis and - extracellular matrix turnover, inflammation and oxidative stress. The autonomic - nervous system and structural remodeling all influence all these - pathophysiological processes, which should not be viewed in isolation. - Understanding such processes would have major implications for the approach to - current pharmaceutical design, to improve our approach to drug management - strategies. -FAU - Kaireviciute, D -AU - Kaireviciute D -AD - Haemostasis, Thrombosis, and Vascular Biology Unit, University Department of - Medicine, City Hospital, Birmingham B18 7QH, UK. -FAU - Aidietis, A -AU - Aidietis A -FAU - Lip, G Y H -AU - Lip GY -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -SB - IM -MH - Animals -MH - Atrial Fibrillation/*drug therapy/etiology/pathology/*physiopathology -MH - *Cardiac Surgical Procedures -MH - Coronary Thrombosis/pathology -MH - Drug Design -MH - Extracellular Matrix/pathology -MH - Heart Atria -MH - Humans -MH - Inflammation/pathology -MH - Myocardium/pathology -MH - Oxidative Stress/physiology -MH - Postoperative Complications/*drug therapy/pathology/*physiopathology -MH - Renin-Angiotensin System/physiology -RF - 174 -EDAT- 2009/10/29 06:00 -MHDA- 2010/01/06 06:00 -CRDT- 2009/10/29 06:00 -PHST- 2009/10/29 06:00 [entrez] -PHST- 2009/10/29 06:00 [pubmed] -PHST- 2010/01/06 06:00 [medline] -AID - 10.2174/138161209789105063 [doi] -PST - ppublish -SO - Curr Pharm Des. 2009;15(29):3367-83. doi: 10.2174/138161209789105063. - -PMID- 21577100 -OWN - NLM -STAT- MEDLINE -DCOM- 20111115 -LR - 20221207 -IS - 1531-7080 (Electronic) -IS - 0268-4705 (Linking) -VI - 26 -IP - 4 -DP - 2011 Jul -TI - Clinical practice and implications of recent diabetes trials. -PG - 288-93 -LID - 10.1097/HCO.0b013e328347b139 [doi] -AB - PURPOSE OF REVIEW: Diabetes is an increasingly prevalent risk factor for coronary - and other vascular disease. Recent trials in patients with diabetes have examined - the effects of intensive glycemic control on cardiovascular outcomes, and - treatment of common concomitant risk factors, in particular hypertension and - dyslipidemia. Optimal revascularization strategies have also been examined. - RECENT FINDINGS: Intensive glycemic control has a beneficial effect on - microvascular but not macrovascular endpoints, with one major trial reporting - increased mortality out to 5 years with intensive treatment. Similarly, - aggressive lowering of SBP to below 120 mmHg produced no advantage over treatment - to 130-140 mmHg. Statins are the best treatment for diabetic dyslipidemia, with - little benefit from adding a fibrate. Medical treatment may be appropriate for - many with diabetes and stable coronary disease. When revascularization is needed, - coronary bypass graft surgery has an advantage over percutaneous coronary - intervention in those at the severe end of the coronary disease spectrum. - SUMMARY: Patients with type 2 diabetes often have multiple cardiovascular risk - factors and require multiple cardiac and diabetes medications. Caution over - aggressive glucose and blood pressure lowering is needed, at least with currently - available drugs. -FAU - Webster, Mark Wi -AU - Webster MW -AD - Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand. - mwebster@adhb.govt.nz -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Cardiol -JT - Current opinion in cardiology -JID - 8608087 -RN - 0 (Blood Glucose) -RN - 0 (Glycated Hemoglobin A) -RN - 0 (Hypoglycemic Agents) -RN - 0 (hemoglobin A1c protein, human) -RN - 9100L32L2N (Metformin) -SB - IM -MH - Blood Glucose/drug effects -MH - Cardiovascular Diseases/*complications/drug therapy/prevention & control -MH - Clinical Trials as Topic -MH - *Diabetes Complications/drug therapy -MH - Diabetes Mellitus, Type 2/*drug therapy -MH - Drug Therapy, Combination -MH - Glycated Hemoglobin/analysis -MH - Humans -MH - Hypoglycemic Agents/*adverse effects/pharmacology -MH - Metformin/pharmacology -MH - Risk Factors -EDAT- 2011/05/18 06:00 -MHDA- 2011/11/16 06:00 -CRDT- 2011/05/18 06:00 -PHST- 2011/05/18 06:00 [entrez] -PHST- 2011/05/18 06:00 [pubmed] -PHST- 2011/11/16 06:00 [medline] -AID - 10.1097/HCO.0b013e328347b139 [doi] -PST - ppublish -SO - Curr Opin Cardiol. 2011 Jul;26(4):288-93. doi: 10.1097/HCO.0b013e328347b139. - -PMID- 20937919 -OWN - NLM -STAT- MEDLINE -DCOM- 20101115 -LR - 20250529 -IS - 1538-3679 (Electronic) -IS - 0003-9926 (Linking) -VI - 170 -IP - 18 -DP - 2010 Oct 11 -TI - Effects of lowering homocysteine levels with B vitamins on cardiovascular - disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized - trials involving 37 485 individuals. -PG - 1622-31 -LID - 10.1001/archinternmed.2010.348 [doi] -AB - Elevated plasma homocysteine levels have been associated with higher risks of - cardiovascular disease, but the effects on disease rates of supplementation with - folic acid to lower plasma homocysteine levels are uncertain. Individual - participant data were obtained for a meta-analysis of 8 large, randomized, - placebo-controlled trials of folic acid supplementation involving 37 485 - individuals at increased risk of cardiovascular disease. The analyses involved - intention-to-treat comparisons of first events during the scheduled treatment - period. There were 9326 major vascular events (3990 major coronary events, 1528 - strokes, and 5068 revascularizations), 3010 cancers, and 5125 deaths. Folic acid - allocation yielded an average 25% reduction in homocysteine levels. During a - median follow-up of 5 years, folic acid allocation had no significant effects on - vascular outcomes, with rate ratios (95% confidence intervals) of 1.01 - (0.97-1.05) for major vascular events, 1.03 (0.97-1.10) for major coronary - events, and 0.96 (0.87-1.06) for stroke. Likewise, there were no significant - effects on vascular outcomes in any of the subgroups studied or on overall - vascular mortality. There was no significant effect on the rate ratios (95% - confidence intervals) for overall cancer incidence (1.05 [0.98-1.13]), cancer - mortality (1.00 [0.85-1.18]) or all-cause mortality (1.02 [0.97-1.08]) during the - whole scheduled treatment period or during the later years of it. Dietary - supplementation with folic acid to lower homocysteine levels had no significant - effects within 5 years on cardiovascular events or on overall cancer or mortality - in the populations studied. -FAU - Clarke, Robert -AU - Clarke R -AD - University of Oxford, England. robert.clarke@ctsu.ox.ac.uk -FAU - Halsey, Jim -AU - Halsey J -FAU - Lewington, Sarah -AU - Lewington S -FAU - Lonn, Eva -AU - Lonn E -FAU - Armitage, Jane -AU - Armitage J -FAU - Manson, JoAnn E -AU - Manson JE -FAU - Bønaa, Kaare H -AU - Bønaa KH -FAU - Spence, J David -AU - Spence JD -FAU - Nygård, Ottar -AU - Nygård O -FAU - Jamison, Rex -AU - Jamison R -FAU - Gaziano, J Michael -AU - Gaziano JM -FAU - Guarino, Peter -AU - Guarino P -FAU - Bennett, Derrick -AU - Bennett D -FAU - Mir, Fraz -AU - Mir F -FAU - Peto, Richard -AU - Peto R -FAU - Collins, Rory -AU - Collins R -CN - B-Vitamin Treatment Trialists' Collaboration -LA - eng -GR - MC_U137686857/MRC_/Medical Research Council/United Kingdom -GR - PG/12/32/29544/BHF_/British Heart Foundation/United Kingdom -GR - CRUK_/Cancer Research UK/United Kingdom -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Research Support, U.S. Gov't, Non-P.H.S. -PT - Review -PL - United States -TA - Arch Intern Med -JT - Archives of internal medicine -JID - 0372440 -RN - 0 (Biomarkers) -RN - 0LVT1QZ0BA (Homocysteine) -RN - 12001-76-2 (Vitamin B Complex) -RN - 935E97BOY8 (Folic Acid) -SB - IM -CIN - Arch Intern Med. 2010 Oct 11;170(18):1631-3. doi: 10.1001/archinternmed.2010.338. - PMID: 20937920 -CIN - Nutr Rev. 2010 Dec;68(12):749. doi: 10.1111/j.1753-4887.2010.00355.x. PMID: - 21140592 -CIN - Evid Based Med. 2011 Aug;16(4):117-8. doi: 10.1136/ebm1204. PMID: 21402567 -MH - Biomarkers/blood -MH - Cardiovascular Diseases/blood/drug therapy/*mortality -MH - Cause of Death -MH - Confidence Intervals -MH - Dietary Supplements -MH - Folic Acid/*therapeutic use -MH - Homocysteine/*blood/*drug effects -MH - Humans -MH - Incidence -MH - Neoplasms/blood/drug therapy/*mortality -MH - Randomized Controlled Trials as Topic -MH - Stroke/blood/mortality -MH - Treatment Failure -MH - Vitamin B Complex/*therapeutic use -FIR - Mir, Fraz -IR - Mir F -FIR - Brown, Morris -IR - Brown M -FIR - Lonn, Eva -IR - Lonn E -FIR - Yusuf, Salim -IR - Yusuf S -FIR - Bønaa, Kaare H -IR - Bønaa KH -FIR - Njolstad, Inger -IR - Njolstad I -FIR - Armitage, Jane -IR - Armitage J -FIR - Bowman, Louise -IR - Bowman L -FIR - Clarke, Robert -IR - Clarke R -FIR - Parish, Sarah -IR - Parish S -FIR - Peto, Richard -IR - Peto R -FIR - Collins, Rory -IR - Collins R -FIR - Jamison, Rex -IR - Jamison R -FIR - Gaziano, J Michael -IR - Gaziano JM -FIR - Guarino, Peter -IR - Guarino P -FIR - Toole, James -IR - Toole J -FIR - Malinow, M Rene -IR - Malinow MR -FIR - Pettigrew, L Creed -IR - Pettigrew LC -FIR - Spence, J David -IR - Spence JD -FIR - Howard, Virginia J -IR - Howard VJ -FIR - Sides, Elizabeth G -IR - Sides EG -FIR - Wang, Chin H -IR - Wang CH -FIR - Stampfer, Meir -IR - Stampfer M -FIR - Manson, JoAnn E -IR - Manson JE -FIR - Glynn, Robert -IR - Glynn R -FIR - Grodstein, Francine -IR - Grodstein F -FIR - Albert, Christine M -IR - Albert CM -FIR - Cook, Nancy R -IR - Cook NR -FIR - Nygård, Ottar -IR - Nygård O -FIR - Ebbing, Marta -IR - Ebbing M -FIR - Nordrehaug, Jan E -IR - Nordrehaug JE -FIR - Nilsen, Dennis W T -IR - Nilsen DW -FIR - Refsum, Hegla -IR - Refsum H -FIR - Vollset, Stein E -IR - Vollset SE -FIR - Clarke, Robert -IR - Clarke R -FIR - Halsey, Jim -IR - Halsey J -FIR - Lewington, Sarah -IR - Lewington S -FIR - Bennett, Derrick -IR - Bennett D -FIR - Collins, Rory -IR - Collins R -EDAT- 2010/10/13 06:00 -MHDA- 2010/11/16 06:00 -CRDT- 2010/10/13 06:00 -PHST- 2010/10/13 06:00 [entrez] -PHST- 2010/10/13 06:00 [pubmed] -PHST- 2010/11/16 06:00 [medline] -AID - 170/18/1622 [pii] -AID - 10.1001/archinternmed.2010.348 [doi] -PST - ppublish -SO - Arch Intern Med. 2010 Oct 11;170(18):1622-31. doi: - 10.1001/archinternmed.2010.348. - -PMID- 16243400 -OWN - NLM -STAT- MEDLINE -DCOM- 20070918 -LR - 20121115 -IS - 0163-7258 (Print) -IS - 0163-7258 (Linking) -VI - 109 -IP - 1-2 -DP - 2006 Jan -TI - Cellular and molecular therapeutic modalities for arterial obstructive syndromes. -PG - 263-73 -AB - Arterial obstructive syndromes result in heart disease, stroke and limb loss, - disability, and mortality. Currently available therapeutics for patients with - these conditions are inadequate or fail in a significant number of patients. The - development of novel therapies for severe coronary arterial disease (CAD), - peripheral arterial disease (PAD), and cerebral vascular disease (CVD) is a major - goal for modern medicine. Molecular and cell-based therapies for arterial - obstructive syndromes have the potential to become clinically useful in the near - future. Molecular therapy employs angiogenic proteins and genes in order to - initiate the development of new blood vessels that by-pass an arterial occlusion. - The induction of a collateral artery system is termed therapeutic angiogenesis or - neovascularization. Proteins have been delivered either directly into the - ischemic area or via a vector encoding an angiogenic gene. Both protein and gene - therapies have been associated with promising preclinical and early phase human - trial results in patients with PAD as well as CAD. However, to date, efficacy has - not been demonstrated in placebo-controlled, large trails. Today's cell-based - therapy is focused on stem cells (SCs) for the treatment of patients after acute - myocardial infarction (AMI) or for patients with severe left ventricular - dysfunction. Stem cells have shown to increase cardiac performance in - uncontrolled, early phase human studies. This improvement is believed to have its - origin in myogenesis and neovascularization. In the following review, we will - cover current state of molecular- and cellular-based treatments for PAD and CAD - that have reached the clinical arena. -FAU - Staudacher, Dawid L -AU - Staudacher DL -AD - Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center, Bruce - Rappaport School of Medicine, Technion-IIT, 7 Michal Street, Haifa 34362, Israel. -FAU - Preis, Meir -AU - Preis M -FAU - Lewis, Basil S -AU - Lewis BS -FAU - Grossman, P Michael -AU - Grossman PM -FAU - Flugelman, Moshe Y -AU - Flugelman MY -LA - eng -PT - Journal Article -PT - Review -DEP - 20051021 -PL - England -TA - Pharmacol Ther -JT - Pharmacology & therapeutics -JID - 7905840 -RN - 0 (Colony-Stimulating Factors) -RN - 0 (Vascular Endothelial Growth Factor A) -RN - 62031-54-3 (Fibroblast Growth Factors) -SB - IM -MH - Animals -MH - Arterial Occlusive Diseases/complications/pathology/*therapy -MH - Colony-Stimulating Factors/physiology -MH - Fibroblast Growth Factors/metabolism -MH - Genetic Therapy -MH - Humans -MH - Neovascularization, Pathologic/complications/pathology/therapy -MH - Neovascularization, Physiologic/drug effects/physiology -MH - Stem Cell Transplantation -MH - Vascular Endothelial Growth Factor A/metabolism -RF - 89 -EDAT- 2005/10/26 09:00 -MHDA- 2007/09/19 09:00 -CRDT- 2005/10/26 09:00 -PHST- 2005/08/01 00:00 [received] -PHST- 2005/08/05 00:00 [accepted] -PHST- 2005/10/26 09:00 [pubmed] -PHST- 2007/09/19 09:00 [medline] -PHST- 2005/10/26 09:00 [entrez] -AID - S0163-7258(05)00177-4 [pii] -AID - 10.1016/j.pharmthera.2005.08.005 [doi] -PST - ppublish -SO - Pharmacol Ther. 2006 Jan;109(1-2):263-73. doi: 10.1016/j.pharmthera.2005.08.005. - Epub 2005 Oct 21. - -PMID- 19001927 -OWN - NLM -STAT- MEDLINE -DCOM- 20090206 -LR - 20090528 -IS - 1558-2027 (Print) -IS - 1558-2027 (Linking) -VI - 9 -IP - 12 -DP - 2008 Dec -TI - Vascular endothelial growth factors in cardiovascular medicine. -PG - 1190-221 -LID - 10.2459/JCM.0b013e3283117d37 [doi] -AB - The discovery of vascular endothelial growth factors (VEGFs) and their receptors - has considerably improved the understanding of the development and function of - endothelial cells. Each member of the VEGF family appears to have a specific - function: VEGF-A induces angiogenesis (i.e. growth of new blood vessels from - preexisting ones), placental growth factor mediates both angiogenesis and - arteriogenesis (i.e. the formation of collateral arteries from preexisting - arterioles), VEGF-C and VEGF-D act mainly as lymphangiogenic factors. The study - of the biology of these endothelial growth factors has allowed a major progress - in the comprehension of the genesis of the vascular system and its abnormalities - observed in various pathologic conditions (atherosclerosis and coronary artery - disease). The role of VEGF in the atherogenic process is still unclear, but - actual evidence suggests both detrimental (development of a neoangiogenetic - process within the atherosclerotic plaque) and beneficial (promotion of - collateral vessel formation) effects. VEGF and other angiogenic growth factors - (fibroblast growth factor), although initially promising in experimental studies - and in initial phase I/II clinical trials in patients with ischemic heart disease - or peripheral arterial occlusive disease, have subsequently failed to show - significant therapeutic improvements in controlled clinical studies. Challenges - still remain about the type or the combination of angiogenic factors to be - administered, the form (protein vs. gene), the route, and the duration of - administration. -FAU - Testa, Ugo -AU - Testa U -AD - Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di - Sanità, Italy. ugo.testa@iss.it -FAU - Pannitteri, Gaetano -AU - Pannitteri G -FAU - Condorelli, Gian Luigi -AU - Condorelli GL -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Cardiovasc Med (Hagerstown) -JT - Journal of cardiovascular medicine (Hagerstown, Md.) -JID - 101259752 -RN - 0 (Membrane Proteins) -RN - 0 (PIGF protein, human) -RN - 0 (Vascular Endothelial Growth Factor A) -RN - 0 (Vascular Endothelial Growth Factor B) -RN - 0 (Vascular Endothelial Growth Factor C) -RN - 0 (Vascular Endothelial Growth Factor D) -SB - IM -MH - Cardiovascular Diseases/physiopathology -MH - Endothelial Cells/physiology -MH - Humans -MH - Membrane Proteins/physiology -MH - Vascular Endothelial Growth Factor A/*physiology/therapeutic use -MH - Vascular Endothelial Growth Factor B/physiology -MH - Vascular Endothelial Growth Factor C/physiology -MH - Vascular Endothelial Growth Factor D/physiology -RF - 262 -EDAT- 2008/11/13 09:00 -MHDA- 2009/02/07 09:00 -CRDT- 2008/11/13 09:00 -PHST- 2008/11/13 09:00 [pubmed] -PHST- 2009/02/07 09:00 [medline] -PHST- 2008/11/13 09:00 [entrez] -AID - 01244665-200812000-00002 [pii] -AID - 10.2459/JCM.0b013e3283117d37 [doi] -PST - ppublish -SO - J Cardiovasc Med (Hagerstown). 2008 Dec;9(12):1190-221. doi: - 10.2459/JCM.0b013e3283117d37. - -PMID- 19948715 -OWN - NLM -STAT- MEDLINE -DCOM- 20110111 -LR - 20250103 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Print) -IS - 0195-668X (Linking) -VI - 31 -IP - 1 -DP - 2010 Jan -TI - Platelet thrombin receptor antagonism and atherothrombosis. -PG - 17-28 -LID - 10.1093/eurheartj/ehp504 [doi] -AB - Clinical manifestations of atherothrombotic disease, such as acute coronary - syndromes, cerebrovascular events, and peripheral arterial disease, are major - causes of mortality and morbidity worldwide. Platelet activation and aggregation - are ultimately responsible for the progression and clinical presentations of - atherothrombotic disease. The current standard of care, dual oral antiplatelet - therapy with aspirin and the P2Y(12) adenosine diphosphate (ADP) receptor - inhibitor clopidogrel, has been shown to improve outcomes in patients with - atherothrombotic disease. However, aspirin and P2Y(12) inhibitors target the - thromboxane A(2) and the ADP P2Y(12) platelet activation pathways and minimally - affect other pathways, while agonists such as thrombin, considered to be the most - potent platelet activator, continue to stimulate platelet activation and - thrombosis. This may help explain why patients continue to experience recurrent - ischaemic events despite receiving such therapy. Furthermore, aspirin and P2Y(12) - receptor antagonists are associated with bleeding risk, as the pathways they - inhibit are critical for haemostasis. The challenge remains to develop therapies - that more effectively inhibit platelet activation without increasing bleeding - complications. The inhibition of the protease-activated receptor-1 (PAR-1) for - thrombin has been shown to inhibit thrombin-mediated platelet activation without - increasing bleeding in pre-clinical models and small-scale clinical trials. PAR-1 - inhibition in fact does not interfere with thrombin-dependent fibrin generation - and coagulation, which are essential for haemostasis. Thus PAR-1 antagonism - coupled with existing dual oral antiplatelet therapy may potentially offer more - comprehensive platelet inhibition without the liability of increased bleeding. -FAU - Angiolillo, Dominick J -AU - Angiolillo DJ -AD - Division of Cardiology, Department of Medicine, University of Florida College of - Medicine -Jacksonville, Shands Jacksonville, 655 West 8th St, Jacksonville, FL - 32209, USA. dominick.angiolillo@jax.ufl.edu -FAU - Capodanno, Davide -AU - Capodanno D -FAU - Goto, Shinya -AU - Goto S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20091130 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (E 5555) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Imines) -RN - 0 (Lactones) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Pyridines) -RN - ZCE93644N2 (vorapaxar) -SB - IM -MH - Fibrinolytic Agents/*therapeutic use -MH - Humans -MH - Imines/therapeutic use -MH - Lactones/therapeutic use -MH - Platelet Activation/*drug effects -MH - *Platelet Aggregation Inhibitors/therapeutic use -MH - Pyridines/therapeutic use -MH - Thrombosis/*prevention & control -PMC - PMC2800923 -EDAT- 2009/12/02 06:00 -MHDA- 2011/01/12 06:00 -PMCR- 2009/11/27 -CRDT- 2009/12/02 06:00 -PHST- 2009/12/02 06:00 [entrez] -PHST- 2009/12/02 06:00 [pubmed] -PHST- 2011/01/12 06:00 [medline] -PHST- 2009/11/27 00:00 [pmc-release] -AID - ehp504 [pii] -AID - 10.1093/eurheartj/ehp504 [doi] -PST - ppublish -SO - Eur Heart J. 2010 Jan;31(1):17-28. doi: 10.1093/eurheartj/ehp504. Epub 2009 Nov - 30. - -PMID- 17265808 -OWN - NLM -STAT- MEDLINE -DCOM- 20070227 -LR - 20181201 -IS - 1660-9379 (Print) -IS - 1660-9379 (Linking) -VI - 2 -IP - 88 -DP - 2006 Nov 22 -TI - [Antiplatelet drugs and intraoperative hemorrhage]. -PG - 2684-7 -AB - Antiplatelet drugs and intraoperative haemorrhage Current literature demonstrates - that there is less risk involved in maintaining anti-aggregant therapy (which - might imply to transfuse more the patients), than in stopping it, which then - increases dangerously the risk of coronary thrombosis. Aspirin, as a secondary - preventive drug, should not be interrupted. Clopidogrel is essential for - protection against thrombosis in areas where the endothelium is not intact. - Unless there is a high hemorrhagic risk in closed cavities (intracranial - surgery), clopidogrel should not be interrupted. Furthermore, any surgical - intervention increasing the coagulability of the platelets, it seems particularly - dangerous to stop such medication perioperatively. -FAU - Chassot, Pierres Guy -AU - Chassot PG -AD - Département de cardiologie CHUV, 1011 Lausanne. pchassot@chuv.ch -FAU - Delabays, Alain -AU - Delabays A -FAU - Ravussin, Patrick -AU - Ravussin P -FAU - Spahn, Donat R -AU - Spahn DR -LA - fre -PT - Journal Article -PT - Review -TT - Antiplaquettaires et hemorragie peropératoire. -PL - Switzerland -TA - Rev Med Suisse -JT - Revue medicale suisse -JID - 101219148 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Platelet Glycoprotein GPIIb-IIIa Complex) -RN - A74586SNO7 (Clopidogrel) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Algorithms -MH - Aspirin/*therapeutic use -MH - Blood Loss, Surgical/*physiopathology -MH - Clopidogrel -MH - Coronary Thrombosis/*prevention & control -MH - Drug Therapy, Combination -MH - Humans -MH - Intraoperative Period -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors -MH - Risk Assessment -MH - Ticlopidine/*analogs & derivatives/therapeutic use -RF - 26 -EDAT- 2007/02/03 09:00 -MHDA- 2007/02/28 09:00 -CRDT- 2007/02/03 09:00 -PHST- 2007/02/03 09:00 [pubmed] -PHST- 2007/02/28 09:00 [medline] -PHST- 2007/02/03 09:00 [entrez] -PST - ppublish -SO - Rev Med Suisse. 2006 Nov 22;2(88):2684-7. - -PMID- 17010548 -OWN - NLM -STAT- MEDLINE -DCOM- 20071018 -LR - 20070806 -IS - 1872-6283 (Electronic) -IS - 0379-0738 (Linking) -VI - 171 -IP - 1 -DP - 2007 Aug 24 -TI - Two consecutive fatal cases of acute myocardial infarction caused by free - floating thrombus in the ascending aorta and review of literature. -PG - 78-83 -AB - Free floating thrombus in the ascending aorta is an uncommon source of acute - myocardial infarction. We report on two cases of young women who died of acute - myocardial infarction caused by a free floating thrombus in the sinus of Valsalva - obstructing the coronary arteries' ostia. The first case reports on a 30-year-old - pregnant woman who anamnestically had episodes with short loss of consciousness - and weakness. The second case presents a 37-year-old woman suffering from - multiple sclerosis with no previous history of thrombotic events. The review of - literature revealed a predominance of women (eight females and three males). - Interestingly, the coronary arteries bear no preference concerning the right - (RCA) or left coronary artery (LCA) being more often occluded by a free floating - thrombus. Especially, younger women (mean age 45.5 years, range 30-59 years) with - no history of cardiac symptoms and without atherosclerotic changes seem to be - predispositioned. The hypothesis that thrombus formation in cases without plaque - disruption may depend on an endothelial erosion which seems to be more common in - younger women and promoted by a hyperthrombogenic state is supported by our two - cases. A comprehensive literature search revealed, that these are the first two - reports on a free floating thrombus being the cause of fatal acute myocardial - infarction in a pregnant woman, respectively, a woman suffering from multiple - sclerosis. -FAU - Knoess, M -AU - Knoess M -AD - Institute of Clinical Pathology, Moltkestrasse 32, 54292 Trier, Germany. - drknoess@aol.com -FAU - Otto, M -AU - Otto M -FAU - Kracht, T -AU - Kracht T -FAU - Neis, P -AU - Neis P -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20060928 -PL - Ireland -TA - Forensic Sci Int -JT - Forensic science international -JID - 7902034 -SB - IM -MH - Adult -MH - Aorta/pathology -MH - Aortic Diseases/*complications/*pathology -MH - Coronary Stenosis/pathology -MH - Coronary Vessels/pathology -MH - Fatal Outcome -MH - Female -MH - Forensic Pathology -MH - Humans -MH - Multiple Sclerosis/complications -MH - Myocardial Infarction/*etiology/pathology -MH - Pregnancy -MH - Pregnancy Complications, Cardiovascular/pathology -MH - Thrombosis/*complications/*pathology -RF - 15 -EDAT- 2006/10/03 09:00 -MHDA- 2007/10/19 09:00 -CRDT- 2006/10/03 09:00 -PHST- 2006/03/09 00:00 [received] -PHST- 2006/07/21 00:00 [revised] -PHST- 2006/08/30 00:00 [accepted] -PHST- 2006/10/03 09:00 [pubmed] -PHST- 2007/10/19 09:00 [medline] -PHST- 2006/10/03 09:00 [entrez] -AID - S0379-0738(06)00552-4 [pii] -AID - 10.1016/j.forsciint.2006.08.025 [doi] -PST - ppublish -SO - Forensic Sci Int. 2007 Aug 24;171(1):78-83. doi: 10.1016/j.forsciint.2006.08.025. - Epub 2006 Sep 28. - -PMID- 19343228 -OWN - NLM -STAT- MEDLINE -DCOM- 20090629 -LR - 20170427 -IS - 1699-3993 (Print) -IS - 1699-3993 (Linking) -VI - 45 -IP - 2 -DP - 2009 Feb -TI - Prasugrel for arterial coronary thrombosis. -PG - 83-91 -LID - 10.1358/dot.2009.45.2.1322478 [doi] -AB - Antiplatelet therapy is the cornerstone of treatment for patients with acute - coronary syndrome undergoing percutaneous coronary intervention. Clopidogrel, in - combination with aspirin, is associated with improvement in longterm vascular - clinical outcomes in these patients and is currently the antiplatelet standard of - care. However, a significant number of patients still experience secondary - ischemic thrombotic events due to potential insufficient platelet inhibition or - noncompliance. Therefore, the development of better and safer antiplatelet agents - is of the utmost priority. Indeed, oral antiplatelet agents, such as aspirin in - the ISIS-2 study and clopidogrel in the COMMIT mega trial, in moderate doses are - among the very few classes of drugs that reduce absolute mortality in patients - after acute vascular thrombotic events. Prasugrel (CS-747; LY-640315), an - experimental third-generation oral thienopyridine, is a specific, irreversible - antagonist of the platelet adenosine diphosphate P2Y(12) receptor. Preclinical - and early phase clinical studies have shown that prasugrel has greater - antiplatelet potency, lower variability in platelet response and faster onset of - inhibition than clopidogrel. However, the doses of the drug chosen for further - prasugrel developments are much higher (about 2.5-2.7 times higher) than those of - conventional clopidogrel regimen(s). The recent TRITON trial assessed - head-to-head prasugrel versus clopidogrel, both in addition to aspirin, and led - to numerous controversies with regard to the fairness of the trial design, - interpretation of its results, and the suitability of the high maintenance - prasugrel dose for chronic preventive human use. We critically review various - aspects of prasugrel development, focusing on the discrepancies between the - official interpretation of the results and actual findings. We conclude that the - benefits of prasugrel are exaggerated and that the risks are underestimated. Very - careful maintenance dose selection and a flawless long-term safety profile for - the new agents will become the keys to the success of future oral antiplatelet - drug development. -CI - Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved. -FAU - Serebruany, Victor -AU - Serebruany V -AD - HeartDrug Research Laboratories, Johns Hopkins University, Maryland 21204, USA. - heartdrug@aol.com -FAU - Makarov, Leonid -AU - Makarov L -LA - eng -PT - Journal Article -PT - Review -PL - Spain -TA - Drugs Today (Barc) -JT - Drugs of today (Barcelona, Spain : 1998) -JID - 101160518 -RN - 0 (Piperazines) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Thiophenes) -RN - G89JQ59I13 (Prasugrel Hydrochloride) -SB - IM -MH - Administration, Oral -MH - Animals -MH - Clinical Trials, Phase I as Topic -MH - Clinical Trials, Phase II as Topic -MH - Clinical Trials, Phase III as Topic -MH - Coronary Thrombosis/*drug therapy -MH - Humans -MH - *Piperazines/pharmacokinetics/pharmacology/therapeutic use -MH - *Platelet Aggregation Inhibitors/pharmacokinetics/pharmacology/therapeutic use -MH - Prasugrel Hydrochloride -MH - *Thiophenes/pharmacokinetics/pharmacology/therapeutic use -RF - 42 -EDAT- 2009/04/04 09:00 -MHDA- 2009/06/30 09:00 -CRDT- 2009/04/04 09:00 -PHST- 2009/04/04 09:00 [entrez] -PHST- 2009/04/04 09:00 [pubmed] -PHST- 2009/06/30 09:00 [medline] -AID - 1322478 [pii] -AID - 10.1358/dot.2009.45.2.1322478 [doi] -PST - ppublish -SO - Drugs Today (Barc). 2009 Feb;45(2):83-91. doi: 10.1358/dot.2009.45.2.1322478. - -PMID- 18645343 -OWN - NLM -STAT- MEDLINE -DCOM- 20080916 -LR - 20080722 -IS - 1536-3686 (Electronic) -IS - 1075-2765 (Linking) -VI - 15 -IP - 4 -DP - 2008 Jul-Aug -TI - Pharmacologic management of isolated low high-density lipoprotein syndrome. -PG - 377-88 -LID - 10.1097/MJT.0b013e318169bc0b [doi] -AB - High-density lipoprotein (HDL) cholesterol is a heterogeneous group of - lipoproteins exhibiting a variety of properties like prostacyclin production - stimulation, decrease in platelet aggregation, endothelial cell apoptosis - inhibition, and low-density lipoprotein oxidation blockade. Epidemiologic studies - have shown an inverse relation between HDL cholesterol levels and cardiovascular - risk. Low HDL cholesterol is associated with increased risk for myocardial - infarction, stroke, sudden death, peripheral artery disease, and postangioplasty - restenosis. In contrast, high HDL levels are associated with longevity and - protection against atherosclerotic disease development. Given the evolving - epidemic of obesity, diabetes mellitus, and metabolic syndrome, the prevalence of - low HDL will continue to rise. In the United States, low HDL is present in 35% of - men, 15% of women, and approximately 63% of patients with coronary artery - disease. Data extracted from the Framingham study highlight that 1-mg increase in - HDL levels decreases by 2% to 3% the risk of cardiovascular disease. There is no - doubt regarding clinical importance about isolated low HDL, but relatively few - clinicians consider a direct therapeutic intervention of this dyslipidemia. In - this sense, lifestyle measures should be the first-line strategy to manage low - HDL levels. On the other hand, pharmacologic options include niacin, fibrates, - and statins. Fibrates appear to reduce risk preferentially in patients with low - HDL with metabolic syndrome, whereas statins reduce risk across all levels of - HDL. Torcetrapib, a cholesteryl esters transfer protein inhibitor, represented a - hope to raise this lipoprotein; however, all clinical trials on this drug had - ceased after ILLUMINATE, RADIANCE and ERASE trials had recorded an increase in - mortality, rates of myocardial infarction, angina, and heart failure. In the near - future, drugs as beta-glucans, Apo-A1 mimetic peptides, and ACAT inhibitors, are - the new promises to treat this condition. -FAU - Bermúdez, Valmore -AU - Bermúdez V -AD - Endocrine and Metabolic Diseases Research Center, University of Zulia, School of - Medicine, Maracaibo, Venezuela. Vbermudez@hotmail.com -FAU - Cano, Raquel -AU - Cano R -FAU - Cano, Clímaco -AU - Cano C -FAU - Bermúdez, Fernando -AU - Bermúdez F -FAU - Arraiz, Nailet -AU - Arraiz N -FAU - Acosta, Luis -AU - Acosta L -FAU - Finol, Freddy -AU - Finol F -FAU - Pabón, María Rebeca -AU - Pabón MR -FAU - Amell, Anilsa -AU - Amell A -FAU - Reyna, Nadia -AU - Reyna N -FAU - Hidalgo, Joaquin -AU - Hidalgo J -FAU - Kendall, Paúl -AU - Kendall P -FAU - Manuel, Velasco -AU - Manuel V -FAU - Hernández, Rafael -AU - Hernández R -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Ther -JT - American journal of therapeutics -JID - 9441347 -RN - 0 (Cholesterol, LDL) -SB - IM -MH - Cardiovascular Diseases/epidemiology/etiology/*prevention & control -MH - Cholesterol, LDL/blood/*drug effects -MH - Controlled Clinical Trials as Topic -MH - Dyslipidemias/complications/*drug therapy/epidemiology -MH - Female -MH - Humans -MH - Life Style -MH - Male -MH - Prevalence -MH - Risk Factors -MH - Syndrome -MH - United States/epidemiology -RF - 84 -EDAT- 2008/07/23 09:00 -MHDA- 2008/09/17 09:00 -CRDT- 2008/07/23 09:00 -PHST- 2008/07/23 09:00 [pubmed] -PHST- 2008/09/17 09:00 [medline] -PHST- 2008/07/23 09:00 [entrez] -AID - 00045391-200807000-00016 [pii] -AID - 10.1097/MJT.0b013e318169bc0b [doi] -PST - ppublish -SO - Am J Ther. 2008 Jul-Aug;15(4):377-88. doi: 10.1097/MJT.0b013e318169bc0b. - -PMID- 28876740 -STAT- Publisher -ISBN- 987-91-85413-19-5 -PB - Swedish Council on Health Technology Assessment (SBU) -CTI - SBU Systematic Review Summaries -DP - 2008 Sep -BTI - Moderately Elevated Blood Pressure: A Systematic Review -AB - Prevalence of High Blood Pressure: An estimated 1.8 million people in Sweden, or - 27% of the adult population (aged 20 or older), have high blood pressure - (hypertension). The condition is just as common among women as men. Of the 1.8 - million Swedish adults with elevated blood pressure: 60% have mild hypertension - (140–159/90–99 mm Hg). 30% have moderate hypertension (160–179/100–109 mm Hg). - 10% have severe hypertension (≥180/≥110 mm Hg). Studies in Sweden find that the - number of patients who reach the treatment goal of blood pressure below 140/90 mm - Hg rarely exceeds 20–30% of those who have been prescribed blood pressure - lowering drugs. Risk Factor for Cardiovascular Disease: Elevated blood pressure - is a risk factor for coronary heart disease, stroke and other cardiovascular - disease, including heart failure (Evidence Grade 1). High blood pressure is also - a risk factor for dementia (Evidence Grade 3). An increase of 20 mm Hg in - systolic pressure or 10 mm Hg in diastolic pressure above 115/75 mm Hg doubles - the risk of death from cardiovascular disease (Evidence Grade 1). The increase is - independent of other risk factors for cardiovascular disease, and it is similar - for women and men (Evidence Grade 1). Women have a lower absolute risk of - cardiovascular disease than men (Evidence Grade 1). However, blood pressure - lowering treatment reduces relative risk equally in women and men (Evidence Grade - 1). Guidelines in Different Countries: The guidelines released in various - countries over the past few years for the management of hypertension are largely - in agreement. The guidelines are basically the same for women and men. All - guidelines: Stress the importance of reaching the treatment goal of blood - pressure below 140/90 mm Hg – below 130/80 mm Hg for patients with diabetes - and/or renal disease. Emphasise the need to consider the patients total risk of - cardiovascular disease rather than treating high blood pressure in isolation. - Recommend a low-dose thiazide diuretic as the first-line therapy or as one of - several first-line therapies. Lifestyle Changes as the Basis of Successful - Treatment: With or without concurrently lowering blood pressure, a number of - lifestyle changes – including physical activity, weight loss, dietary - modifications, stress management, smoking cessation and the avoidance of - excessive alcohol consumption – can minimise the risk factors for cardiovascular - disease (Evidence Grade 1). Lifestyle measures can reduce the need for drug - therapy and should form the basis for treating people with high blood pressure - (hypertensives) (Evidence Grade 1). Smoking cessation measures should also be a - priority for hypertensives and can generate major treatment benefits (Evidence - Grade 1). Pharmacological Treatment: Blood pressure lowering treatment reduces - the risk of stroke, myocardial infarction and premature death in hypertensives of - both sexes (Evidence Grade 1). The various groups of blood pressure lowering - drugs – thiazide diuretics, angiotensin converting enzyme (ACE) inhibitors, - calcium antagonists, angiotensin receptor blockers (ARBs) and beta blockers – - ordinarily used in Sweden are equally effective (reduction of approximately 10/5 - mm Hg) when administered separately (Evidence Grade 1). Since the efficacy of - different types of drugs can vary for a particular individual, switching to or - adding one or more medications may be required in order to lower blood pressure - sufficiently. For people with uncomplicated hypertension, all the major drug - groups – thiazide diuretics, ACE inhibitors, calcium antagon- ists and ARBs – are - equally effective in minimising the risk of cardiovascular disease (Evidence - Grade 1). Beta blockers reduce the risk of stroke to a lesser extent (Evidence - Grade 1). That is partly due to poorer reduction in blood pressure (Evidence - Grade 2). Following stroke, blood pressure lowering drugs reduce the risk of - myocardial infarction (Evidence Grade 3) and stroke recurrence (Evidence Grade - 1). Treatment is equally effective with or without concurrent hypertension. At - least half of all patients with type 2 diabetes also have hypertension. The - effect of hypertension treatment on the absolute risk of cardiovascular disease - morbidity and mortality is greater with concurrent diabetes (Evidence Grade 1). - In people with type 2 diabetes, the impact on relative risk is also greater - (Evidence Grade 1). Patients whose treatment is based on drugs (ACE inhibitors - and ARBs) that directly affect the renin-angiotensin-aldosterone system are less - likely to develop type 2 diabetes than those whose treatment is based on a - thiazide diuretic combined with a beta blocker or on a calcium antagonist - (Evidence Grade 2). In patients with high risk (multiple risk factors) of - cardiovascular disease and concurrent type 2 diabetes mellitus, blockade of the - renin–angiotensin–aldosterone system may reduce the risk beyond the impact of - simply lowering blood pressure (ACE inhibitors – Evidence Grade 2, ARBs – - Evidence Grade 3). Blood pressure lowering treatment counteracts clinically - relevant deterioration of renal function (Evidence Grade 1). No difference with - regard to the long-term effect on renal function has been shown among the various - groups of blood pressure lowering drugs in patients who have mild to moderate - hypertension without other concurrent kidney complications. This report did not - review treatment of patients with diabetes and impaired renal function. - Hypertension leads to thickening of the heart muscle. Blood pressure lowering - treatment reduces left ventricular mass (Evidence Grade 1). Such a reduction is - associated with a lower risk of cardiovascular disease (Evidence Grade 2). - Economic Aspects: Sales of blood pressure lowering drugs for the indication of - hypertension more than doubled from 70 defined daily doses (DDSs) per 1 000 - Swedes in 1992 to 155 in 2002. Costs for drug treatment of hypertension totalled - SEK 1,656 million in 2002. Since satisfactory treatment of everyone with - hypertension would involve both a larger number of patients and more medications - per person, total drug costs would rise (Evidence Grade 2). Choice of medication - has a major impact on both drug costs and cost effectiveness. Prescribing the - least expensive equiva- lent medication whenever possible would reduce drug costs - and improve cost effectiveness compared with current pre- scription patterns - (Evidence Grade 2). Treatment of uncomplicated hypertension with the least - expensive equivalent drug entails cost savings for older women, as well as - middle-aged and older men. Improving the treatment of patients with moderate to - high risk is more cost-effective than treating more people with low risk - (Evidence Grade 2). Ethical aspects: The ethical dilemma of treating an - apparently healthy person with drugs for what is likely to be a long period of - time should be weighed against the risks associated with withholding treatment - that may prevent serious disease. Principles of Evidence Grading Quality refers - to the scientific quality of a particular study and its ability to reliably - answer a specific question. Evidence Grade refers to the total scientific - evidence for a conclusion, i.e., how many high-quality studies support the - conclusion. Evidence Grade 1 A conclusion assigned Evidence Grade 1 is supported - by at least two studies with high quality among the total scientific evidence. If - some studies are at variance with the conclusion, the evidence grade may be - lower. Evidence Grade 2 A conclusion assigned Evidence Grade 2 is supported by at - least one study with high quality and two studies with moderate quality among the - total scientific evidence. If some studies are at variance with the conclusion, - the evidence grade may be lower. Evidence Grade 3 A conclusion assigned Evidence - Grade 3 is supported by at least two studies with moderate quality among the - total scientific evidence. If some studies are at variance with the conclusion, - the evidence grade may be lower. -CI - Copyright © 2008 by the Swedish Council on Health Technology Assessment. -CN - Swedish Council on Health Technology Assessment -LA - eng -PT - Review -PT - Book -PL - Stockholm -EDAT- 2008/09/01 00:00 -CRDT- 2008/09/01 00:00 -AID - NBK448011 [bookaccession] - -PMID- 21331766 -OWN - NLM -STAT- MEDLINE -DCOM- 20110927 -LR - 20250529 -IS - 1534-6242 (Electronic) -IS - 1523-3804 (Print) -IS - 1523-3804 (Linking) -VI - 13 -IP - 3 -DP - 2011 Jun -TI - Lecithin cholesterol acyltransferase: an anti- or pro-atherogenic factor? -PG - 249-56 -LID - 10.1007/s11883-011-0171-6 [doi] -AB - Lecithin cholesterol acyl transferase (LCAT) is a plasma enzyme that esterifies - cholesterol and raises high-density lipoprotein cholesterol, but its role in - atherosclerosis is not clearly established. Studies of various animal models have - yielded conflicting results, but studies done in rabbits and non-human primates, - which more closely simulate human lipoprotein metabolism, indicate that LCAT is - likely atheroprotective. Although suggestive, there are also no biomarker studies - that mechanistically link LCAT with cardiovascular disease. Imaging studies of - patients with LCAT deficiency have also not yielded a clear answer to the role of - LCAT in atherosclerosis. Recombinant LCAT, however, is currently being developed - as a therapeutic product for enzyme replacement therapy of patients with genetic - disorders of LCAT for the prevention and/or treatment of renal disease, but it - may also have value for the treatment of acute coronary syndrome. -FAU - Rousset, Xavier -AU - Rousset X -AD - Institutes of Health, National Heart, Lung and Blood Institute, Cardio-Pulmonary - Branch, Lipoprotein Metabolism Section, 10 Center Dr Bldg. 10/8N224, Bethesda, MD - 20814, USA. roussetx@nhlbi.nih.gov -FAU - Shamburek, Robert -AU - Shamburek R -FAU - Vaisman, Boris -AU - Vaisman B -FAU - Amar, Marcelo -AU - Amar M -FAU - Remaley, Alan T -AU - Remaley AT -LA - eng -GR - ZIA HL006092/ImNIH/Intramural NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Intramural -PT - Review -PL - United States -TA - Curr Atheroscler Rep -JT - Current atherosclerosis reports -JID - 100897685 -RN - 0 (Cholesterol Esters) -RN - 0 (Cholesterol, HDL) -RN - 0 (Fatty Acids) -RN - EC 2.3.1.43 (Phosphatidylcholine-Sterol O-Acyltransferase) -SB - IM -MH - Animals -MH - *Atherosclerosis/enzymology/genetics -MH - Biological Transport/genetics -MH - Cholesterol Esters/metabolism -MH - Cholesterol, HDL/genetics/*metabolism -MH - Disease Models, Animal -MH - Drug Evaluation, Preclinical -MH - Fatty Acids/metabolism -MH - Humans -MH - Lecithin Cholesterol Acyltransferase Deficiency/*enzymology/genetics -MH - Lipid Metabolism/*genetics -MH - Mice -MH - *Phosphatidylcholine-Sterol O-Acyltransferase/genetics/metabolism/therapeutic use -MH - Rabbits -MH - Saimiri -PMC - PMC3794709 -MID - NIHMS508294 -COIS- Disclosure The authors report not potential conflicts of interest relevant to - this article. -EDAT- 2011/02/19 06:00 -MHDA- 2011/09/29 06:00 -PMCR- 2013/10/10 -CRDT- 2011/02/19 06:00 -PHST- 2011/02/19 06:00 [entrez] -PHST- 2011/02/19 06:00 [pubmed] -PHST- 2011/09/29 06:00 [medline] -PHST- 2013/10/10 00:00 [pmc-release] -AID - 10.1007/s11883-011-0171-6 [doi] -PST - ppublish -SO - Curr Atheroscler Rep. 2011 Jun;13(3):249-56. doi: 10.1007/s11883-011-0171-6. - -PMID- 25018896 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20220316 -IS - 2157-1724 (Print) -IS - 2157-1716 (Electronic) -IS - 2157-1716 (Linking) -VI - 1 -IP - 1 -DP - 2011 Jun -TI - Arterial aging and arterial disease: interplay between central hemodynamics, - cardiac work, and organ flow-implications for CKD and cardiovascular disease. -PG - 10-12 -AB - Cardiovascular disease is an important cause of morbidity and mortality in - patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). - All epidemiological studies have clearly shown that accelerated arterial and - cardiac aging is characteristic of these populations. Arterial premature aging is - heterogeneous. It principally involves the aorta and central capacitive arteries, - and is characterized by preferential aortic stiffening and disappearance of - stiffness/impedance gradients between the central and peripheral arteries. These - changes have a double impact: on the heart, upstream, with left ventricular - hypertrophy and decreased coronary perfusion; and, downstream, on renal and brain - microcirculation (decrease in glomerular filtration and cognitive functions). - Multifactorial at origin, the pathophysiology of aortic 'progeria' and - microvascular disorders in CKD/ESRD is not well understood and should be the - focus of interest in future studies. -FAU - London, Gerard -AU - London G -AD - INSERM U970, Hôpital Européen Georges Pompidou , Paris, France. -FAU - Covic, Adrian -AU - Covic A -AD - Clinic of Nephrology, C.I. Parhon University Hospital, Gr. T. Popa University of - Medicine and Pharmacy , Iasi, Romania. -FAU - Goldsmith, David -AU - Goldsmith D -AD - Renal Unit, Guy's and St Thomas' NHS Foundation Hospital, King's Health Partners - , London, UK. -FAU - Wiecek, Andrzej -AU - Wiecek A -AD - Division of Internal Medicine and Nephrology, Department of Nephrology, - Endocrinology and Metabolic Diseases, Medical University of Silesia , Katowice, - Poland. -FAU - Suleymanlar, Gultekin -AU - Suleymanlar G -AD - Nephrology Division, Department of Medicine, Akdeniz University Medical School , - Antalya, Turkey. -FAU - Ortiz, Alberto -AU - Ortiz A -AD - Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo - Alvarez de Toledo , Madrid, Spain. -FAU - Massy, Ziad -AU - Massy Z -AD - INSERM ERI-12 (EA 4292) , Amiens, France ; Amiens University Hospital and the - Jules Verne University of Picardie , Amiens, France. -FAU - Lindholm, Bengt -AU - Lindholm B -AD - Department of Clinical Science, Intervention and Technology, Karolinska - Institutet , Stockholm, Sweden. -FAU - Martinez-Castelao, Alberto -AU - Martinez-Castelao A -AD - Hospital Universitario de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , - Barcelona, Spain. -FAU - Fliser, Danilo -AU - Fliser D -AD - Department of Internal Medicine IV, Saarland University Medical Centre , - Homburg/Saar, Germany. -FAU - Agarwal, Rajiv -AU - Agarwal R -AD - Indiana University and VAMC , Indianapolis, Indiana, USA. -FAU - Jager, Kitty J -AU - Jager KJ -AD - ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, - University of Amsterdam , Amsterdam, The Netherlands. -FAU - Dekker, Friedo W -AU - Dekker FW -AD - Department of Clinical Epidemiology, Leiden University Medical Center , Leiden, - The Netherlands. -FAU - Blankestijn, Peter J -AU - Blankestijn PJ -AD - Department of Nephrology, University Medical Center , Utrecht, The Netherlands. -FAU - Zoccali, Carmine -AU - Zoccali C -AD - Nephrology, Dialysis and Transplantation Unit and CNR-IBIM Clinical Epidemiology - and Pathophysiology of Renal Diseases and Hypertension , Reggio Calabria, Italy. -CN - for EUropean REnal and CArdiovascular Medicine working group of the European - Renal Association–European Dialysis and Transplant Association (ERA–EDTA) -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Kidney Int Suppl (2011) -JT - Kidney international supplements -JID - 101562008 -PMC - PMC4089718 -OTO - NOTNLM -OT - aging -OT - arterial stiffness -OT - arteriosclerosis -OT - end-stage renal disease -OT - pressure waves -EDAT- 2011/06/01 00:00 -MHDA- 2011/06/01 00:01 -PMCR- 2014/07/09 -CRDT- 2014/07/15 06:00 -PHST- 2014/07/15 06:00 [entrez] -PHST- 2011/06/01 00:00 [pubmed] -PHST- 2011/06/01 00:01 [medline] -PHST- 2014/07/09 00:00 [pmc-release] -AID - S2157-1716(15)31004-2 [pii] -AID - 10.1038/kisup.2011.5 [doi] -PST - ppublish -SO - Kidney Int Suppl (2011). 2011 Jun;1(1):10-12. doi: 10.1038/kisup.2011.5. - -PMID- 19290075 -OWN - NLM -STAT- MEDLINE -DCOM- 20090504 -LR - 20211020 -IS - 2385-2070 (Electronic) -IS - 1723-2007 (Print) -IS - 1723-2007 (Linking) -VI - 7 -IP - 1 -DP - 2009 Jan -TI - Antithrombotic treatment before and after peripheral artery percutaneous - angioplasty. -PG - 18-23 -LID - 10.2450/2008.0008-08b [doi] -FAU - Visonà, Adriana -AU - Visonà A -AD - Unità di Angiologia, Ospedale San Giacomo, Castelfranco Veneto (TV), Italy. - adriana.visona@ulssasolo.ven.it -FAU - Tonello, Diego -AU - Tonello D -FAU - Zalunardo, Beniamino -AU - Zalunardo B -FAU - Irsara, Sandro -AU - Irsara S -FAU - Liessi, Guido -AU - Liessi G -FAU - Marigo, Lucia -AU - Marigo L -FAU - Zotta, Laura -AU - Zotta L -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Blood Transfus -JT - Blood transfusion = Trasfusione del sangue -JID - 101237479 -RN - 0 (Antibodies, Monoclonal) -RN - 0 (Drug Combinations) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Heparin, Low-Molecular-Weight) -RN - 0 (Immunoglobulin Fab Fragments) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Pyridines) -RN - 0 (thienopyridine) -RN - 64ALC7F90C (Dipyridamole) -RN - R16CO5Y76E (Aspirin) -RN - X85G7936GV (Abciximab) -SB - IM -MH - Abciximab -MH - *Angioplasty, Balloon, Coronary/rehabilitation -MH - Antibodies, Monoclonal/therapeutic use -MH - Aspirin/therapeutic use -MH - Coronary Restenosis/*prevention & control -MH - Dipyridamole/therapeutic use -MH - Drug Combinations -MH - Fibrinolytic Agents/therapeutic use -MH - Heparin, Low-Molecular-Weight/therapeutic use -MH - Humans -MH - Immunoglobulin Fab Fragments/therapeutic use -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Pyridines/therapeutic use -MH - Randomized Controlled Trials as Topic -MH - *Thrombolytic Therapy -PMC - PMC2652231 -EDAT- 2009/03/18 09:00 -MHDA- 2009/05/05 09:00 -PMCR- 2009/01/01 -CRDT- 2009/03/18 09:00 -PHST- 2008/03/03 00:00 [received] -PHST- 2008/07/16 00:00 [accepted] -PHST- 2009/03/18 09:00 [entrez] -PHST- 2009/03/18 09:00 [pubmed] -PHST- 2009/05/05 09:00 [medline] -PHST- 2009/01/01 00:00 [pmc-release] -AID - blt-07-018 [pii] -AID - 10.2450/2008.0008-08b [doi] -PST - ppublish -SO - Blood Transfus. 2009 Jan;7(1):18-23. doi: 10.2450/2008.0008-08b. - -PMID- 18182064 -OWN - NLM -STAT- MEDLINE -DCOM- 20080908 -LR - 20181113 -IS - 1582-1838 (Print) -IS - 1582-4934 (Electronic) -IS - 1582-1838 (Linking) -VI - 12 -IP - 2 -DP - 2008 Apr -TI - The paradigm of postconditioning to protect the heart. -PG - 435-58 -LID - 10.1111/j.1582-4934.2007.00210.x [doi] -AB - Ischaemic preconditioning limits the damage induced by subsequent - ischaemia/reperfusion (I/R). However, preconditioning is of little practical use - as the onset of an infarction is usually unpredictable. Recently, it has been - shown that the heart can be protected against the extension of I/R injury if - brief (10-30 sec.) coronary occlusions are performed just at the beginning of the - reperfusion. This procedure has been called postconditioning (PostC). It can also - be elicited at a distant organ, termed remote PostC, by intermittent pacing - (dyssynchrony-induced PostC) and by pharmacological interventions, that is - pharmacological PostC. In particular, brief applications of intermittent - bradykinin or diazoxide at the beginning of reperfusion reproduce PostC - protection. PostC reduces the reperfusion-induced injury, blunts oxidant-mediated - damages and attenuates the local inflammatory response to reperfusion. PostC - induces a reduction of infarct size, apoptosis, endothelial dysfunction and - activation, neutrophil adherence and arrhythmias. Whether it reduces stunning is - not clear yet. Similar to preconditioning, PostC triggers signalling pathways and - activates effectors implicated in other cardioprotective manoeuvres. Adenosine - and bradykinin are involved in PostC triggering. PostC triggers survival kinases - (RISK), including Akappat and extracellular signal-regulated kinase (ERK). Nitric - oxide, via nitric oxide synthase and non-enzymatic production, cyclic guanosine - monophosphate (cGMP) and protein kinases G (PKG) participate in PostC. - PostC-induced protection also involves an early redox-sensitive mechanism, and - mitochondrial adenosine-5' -triphosphate (ATP)-sensitive K(+) and PKC activation. - Protective pathways activated by PostC appear to converge on mitochondrial - permeability transition pores, which are inhibited by acidosis and glycogen - synthase kinase-3beta (GSK-3beta). In conclusion, the first minutes of - reperfusion represent a window of opportunity for triggering the aforementioned - mediators which will in concert lead to protection against reperfusion injury. - Pharmacological PostC and possibly remote PostC may have a promising future in - clinical scenario. -FAU - Penna, C -AU - Penna C -AD - Dipartimento di Scienze Cliniche e Biologiche dell'Università di Torino, - Orbassano, Torino, Italy. -FAU - Mancardi, D -AU - Mancardi D -FAU - Raimondo, S -AU - Raimondo S -FAU - Geuna, S -AU - Geuna S -FAU - Pagliaro, P -AU - Pagliaro P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20071220 -PL - England -TA - J Cell Mol Med -JT - Journal of cellular and molecular medicine -JID - 101083777 -RN - 0 (Vasodilator Agents) -RN - 8L70Q75FXE (Adenosine Triphosphate) -RN - O5CB12L4FN (Diazoxide) -RN - S8TIM42R2W (Bradykinin) -SB - IM -MH - Adenosine Triphosphate/metabolism -MH - Animals -MH - Bradykinin/pharmacology -MH - Coronary Occlusion/*etiology -MH - Diazoxide/pharmacology -MH - Humans -MH - Models, Cardiovascular -MH - Myocardial Infarction/*drug therapy/pathology -MH - *Myocardial Reperfusion -MH - Myocardial Reperfusion Injury/*prevention & control -MH - Myocardium -MH - Oxidation-Reduction -MH - *Signal Transduction -MH - Time Factors -MH - Vasodilator Agents/pharmacology -PMC - PMC3822534 -EDAT- 2008/01/10 09:00 -MHDA- 2008/09/09 09:00 -PMCR- 2008/04/01 -CRDT- 2008/01/10 09:00 -PHST- 2008/01/10 09:00 [pubmed] -PHST- 2008/09/09 09:00 [medline] -PHST- 2008/01/10 09:00 [entrez] -PHST- 2008/04/01 00:00 [pmc-release] -AID - JCMM210 [pii] -AID - 10.1111/j.1582-4934.2007.00210.x [doi] -PST - ppublish -SO - J Cell Mol Med. 2008 Apr;12(2):435-58. doi: 10.1111/j.1582-4934.2007.00210.x. - Epub 2007 Dec 20. - -PMID- 17981547 -OWN - NLM -STAT- MEDLINE -DCOM- 20071211 -LR - 20190902 -IS - 1093-9946 (Print) -IS - 1093-4715 (Linking) -VI - 13 -DP - 2008 Jan 1 -TI - Making the heart resistant to infarction: how can we further decrease infarct - size? -PG - 284-301 -AB - Acute myocardial infarction (AMI) following coronary artery occlusion is a common - cause of mortality and morbidity world-wide. Patients currently receive - reperfusion therapy as the only anti-infarct intervention. A number of agents - have been evaluated to further improve myocardial salvage, but until recently, - none has demonstrated clear efficacy in clinical trials. A new target of - cardioprotection, the Reperfusion Injury Salvage Kinase (RISK) pathway, has been - proposed. These kinases are involved in mediating the cardioprotection of - myocardial preconditioning and postconditioning induced by short non-lethal - cycles of ischemia/reperfusion performed before (preconditioning) or just after - (postconditioning) a lethal ischemic insult. Many pharmacological interventions - are now available that protect the heart by activating the RISK pathway at the - time of reperfusion. The present review will examine the efficacy of several - strategies that have been proposed to protect the acutely ischemic myocardium - including (1) those intended to directly alter adverse reperfusion events (e.g., - calcium overload and free radical attack), (2) those based on activation of the - RISK pathway including postconditioning, and (3) myocardial cooling. -FAU - Tissier, Renaud -AU - Tissier R -AD - INSERM, Unite 841, Creteil, F-94000 France. -FAU - Berdeaux, Alain -AU - Berdeaux A -FAU - Ghaleh, Bijan -AU - Ghaleh B -FAU - Couvreur, Nicolas -AU - Couvreur N -FAU - Krieg, Thomas -AU - Krieg T -FAU - Cohen, Michael V -AU - Cohen MV -FAU - Downey, James M -AU - Downey JM -LA - eng -GR - HL-20648/HL/NHLBI NIH HHS/United States -GR - HL-50688/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080101 -PL - United States -TA - Front Biosci -JT - Frontiers in bioscience : a journal and virtual library -JID - 9709506 -RN - 0 (Insulin) -RN - 0 (Reactive Oxygen Species) -RN - IY9XDZ35W2 (Glucose) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Apoptosis -MH - Calcium/metabolism -MH - Coronary Occlusion/pathology -MH - Glucose/metabolism -MH - Humans -MH - Inflammation -MH - Insulin/metabolism -MH - Ischemic Preconditioning, Myocardial/methods/*trends -MH - Models, Biological -MH - Myocardial Infarction/*physiopathology/*prevention & control -MH - Myocardium/metabolism -MH - Reactive Oxygen Species -MH - Reperfusion -MH - Time Factors -RF - 219 -EDAT- 2007/11/06 09:00 -MHDA- 2007/12/12 09:00 -CRDT- 2007/11/06 09:00 -PHST- 2007/11/06 09:00 [pubmed] -PHST- 2007/12/12 09:00 [medline] -PHST- 2007/11/06 09:00 [entrez] -AID - 2679 [pii] -AID - 10.2741/2679 [doi] -PST - epublish -SO - Front Biosci. 2008 Jan 1;13:284-301. doi: 10.2741/2679. - -PMID- 24167539 -OWN - NLM -STAT- MEDLINE -DCOM- 20140619 -LR - 20241219 -IS - 1915-7398 (Electronic) -IS - 1915-7398 (Linking) -VI - 13 -IP - 5 -DP - 2013 -TI - In-home care for optimizing chronic disease management in the community: an - evidence-based analysis. -PG - 1-65 -AB - BACKGROUND: The emerging attention on in-home care in Canada assumes that chronic - disease management will be optimized if it takes place in the community as - opposed to the health care setting. Both the patient and the health care system - will benefit, the latter in terms of cost savings. OBJECTIVES: To compare the - effectiveness of care delivered in the home (i.e., in-home care) with no home - care or with usual care/care received outside of the home (e.g., health care - setting). DATA SOURCES: A literature search was performed on January 25, 2012, - using OVID MEDLINE, OVID MEDLINE In-Process and Other Non-Indexed Citations, OVID - EMBASE, EBSCO Cumulative Index to Nursing & Allied Health Literature (CINAHL), - the Wiley Cochrane Library, and the Centre for Reviews and Dissemination - database, for studies published from January 1, 2006, until January 25, 2012. - REVIEW METHODS: An evidence-based analysis examined whether there is a difference - in mortality, hospital utilization, health-related quality of life (HRQOL), - functional status, and disease-specific clinical measures for in-home care - compared with no home care for heart failure, atrial fibrillation, coronary - artery disease, stroke, chronic obstructive pulmonary disease, diabetes, chronic - wounds, and chronic disease / multimorbidity. Data was abstracted and analyzed in - a pooled analysis using Review Manager. When needed, subgroup analysis was - performed to address heterogeneity. The quality of evidence was assessed by - GRADE. RESULTS: The systematic literature search identified 1,277 citations from - which 12 randomized controlled trials met the study criteria. Based on these, a - 12% reduced risk for in-home care was shown for the outcome measure of combined - events including all-cause mortality and hospitalizations (relative risk [RR]: - 0.88; 95% CI: 0.80-0.97). Patients receiving in-home care had an average of 1 - less unplanned hospitalization (mean difference [MD]: -1.03; 95% CI: -1.53 to - -0.53) and an average of 1 less emergency department (ED) visit (MD: -1.32; 95% - CI: -1.87 to -0.77). A beneficial effect of in-home care was also shown on - activities of daily living (MD: -0.14; 95% CI: -0.27 to -0.01), including less - difficulty dressing above the waist or below the waist, grooming, - bathing/showering, toileting, and feeding. These results were based on moderate - quality of evidence. Additional beneficial effects of in-home care were shown for - HRQOL although this was based on low quality of evidence. LIMITATIONS: Different - characterization of outcome measures across studies prevented the inclusion of - all eligible studies for analysis. CONCLUSIONS: In summary, education-based - in-home care is effective at improving outcomes of patients with a range of heart - disease severity when delivered by nurses during a single home visit or on an - ongoing basis. In-home visits by occupational therapists and physical therapists - targeting modification of tasks and the home environment improved functional - activities for community-living adults with chronic disease. -CN - Health Quality Ontario -LA - eng -PT - Journal Article -PT - Review -DEP - 20130901 -PL - Canada -TA - Ont Health Technol Assess Ser -JT - Ontario health technology assessment series -JID - 101521610 -SB - IM -MH - Chronic Disease/mortality/*therapy -MH - *Disease Management -MH - Evidence-Based Practice -MH - Home Care Services/economics/*trends -MH - Hospitalization/economics/*trends -MH - Humans -MH - Nurses/statistics & numerical data -MH - Occupational Therapy/statistics & numerical data -MH - Ontario/epidemiology -MH - Patient Education as Topic -MH - Patient Satisfaction -MH - Physical Therapists/statistics & numerical data -MH - *Quality of Life -MH - Treatment Outcome -PMC - PMC3804052 -EDAT- 2013/10/30 06:00 -MHDA- 2014/06/20 06:00 -PMCR- 2013/09/01 -CRDT- 2013/10/30 06:00 -PHST- 2013/10/30 06:00 [entrez] -PHST- 2013/10/30 06:00 [pubmed] -PHST- 2014/06/20 06:00 [medline] -PHST- 2013/09/01 00:00 [pmc-release] -PST - epublish -SO - Ont Health Technol Assess Ser. 2013 Sep 1;13(5):1-65. eCollection 2013. - -PMID- 22273530 -OWN - NLM -STAT- MEDLINE -DCOM- 20120710 -LR - 20220310 -IS - 1525-139X (Electronic) -IS - 0894-0959 (Linking) -VI - 25 -IP - 1 -DP - 2012 Jan-Feb -TI - Diastolic heart failure in dialysis patients: mechanisms, diagnostic approach, - and treatment. -PG - 35-41 -LID - 10.1111/j.1525-139X.2011.01011.x [doi] -AB - Heart failure (HF) is very common in the general population, and risk factors for - HF, such as coronary artery disease, diabetes, obesity, and hypertension, are - frequently present in patients with CKD. Therefore, HF is also an important cause - of morbidity and mortality in this population. Diastolic heart failure (DHF), - also called HF with preserved ejection fraction, refers to a clinical syndrome in - which patients have symptoms and signs of HF, normal or near normal left - ventricular (LV) systolic function, and evidence of diastolic dysfunction (e.g., - abnormal LV filling and elevated filling pressure). Recent data suggest that HF - with normal ejection fraction is even more common in patients than HF with low - ejection fraction, including those on hemodialysis. Not surprisingly, DHF is a - strong predictor of death in CKD patients. In this article, we review the - information available on the mechanisms, clinical presentation, impact, and - potential interventions in DHF based on evidence from CKD patients, as well as - evidence from the general population potentially applicable to the CKD - population. -CI - © 2012 Wiley Periodicals, Inc. -FAU - Pecoits-Filho, Roberto -AU - Pecoits-Filho R -AD - Center for Health and Biological Sciences, Pontificia Universidade Católica do - Paraná, Curitiba, Brazil. -FAU - Bucharles, Sérgio -AU - Bucharles S -FAU - Barberato, Silvio H -AU - Barberato SH -LA - eng -PT - Journal Article -PT - Research Support, U.S. Gov't, P.H.S. -PT - Review -PL - United States -TA - Semin Dial -JT - Seminars in dialysis -JID - 8911629 -RN - 0 (Sodium Potassium Chloride Symporter Inhibitors) -RN - 0 (Vasodilator Agents) -SB - IM -MH - Cardiac Catheterization/*methods -MH - Echocardiography, Doppler/*methods -MH - Glomerular Filtration Rate -MH - *Heart Failure, Diastolic/drug therapy/etiology/physiopathology -MH - Humans -MH - Kidney Failure, Chronic/*complications/physiopathology/therapy -MH - Prognosis -MH - Renal Dialysis -MH - Risk Factors -MH - Sodium Potassium Chloride Symporter Inhibitors/administration & - dosage/*therapeutic use -MH - Stroke Volume -MH - Vasodilator Agents/*therapeutic use -MH - Ventricular Function, Left/*physiology -MH - Ventricular Pressure -EDAT- 2012/01/26 06:00 -MHDA- 2012/07/11 06:00 -CRDT- 2012/01/26 06:00 -PHST- 2012/01/26 06:00 [entrez] -PHST- 2012/01/26 06:00 [pubmed] -PHST- 2012/07/11 06:00 [medline] -AID - 10.1111/j.1525-139X.2011.01011.x [doi] -PST - ppublish -SO - Semin Dial. 2012 Jan-Feb;25(1):35-41. doi: 10.1111/j.1525-139X.2011.01011.x. - -PMID- 25520987 -STAT- Publisher -PB - Agency for Healthcare Research and Quality (US) -CTI - AHRQ Technology Assessments -DP - 2006 Oct 3 -BTI - Non-Invasive Imaging for Coronary Artery Disease -AB - This report describes an evaluation of the available scientific evidence on - direct non-invasive imaging tests (NITs) for coronary artery disease. In - particular, we focus on six key questions provided by the Agency for Healthcare - Research and Quality (AHRQ) and the Centers for Medicare and Medicaid Services - (CMS). The objective of this report is to provide background information to the - Medicare Coverage Advisory Committee (MCAC) in their review of these questions - during their May 2006 meeting. The six key questions examine the degree to which - current evidence supports confident judgments about the use of NITs in the - assessment of coronary anatomy in clinical practice. The two NITs that are - examined in detail in this report are computed tomographic angiography (CTA) and - magnetic resonance angiography (MRA) for evaluating native coronary arteries. In - addition, we consider technologies on the horizon, as well as the general issue - of establishing the value of NITs in specific clinical contexts in which coronary - disease is being considered. -FAU - Matchar, David B -AU - Matchar DB -AD - Duke Evidence-based Practice Center -FAU - Mark, Daniel B -AU - Mark DB -AD - Duke Evidence-based Practice Center -FAU - Patel, Manesh R -AU - Patel MR -AD - Duke Evidence-based Practice Center -FAU - Hurwitz, Lynne M -AU - Hurwitz LM -AD - Duke Evidence-based Practice Center -FAU - Orlando, Lori A -AU - Orlando LA -AD - Duke Evidence-based Practice Center -FAU - McCrory, Douglas C -AU - McCrory DC -AD - Duke Evidence-based Practice Center -FAU - Sanders, Gillian D -AU - Sanders GD -AD - Duke Evidence-based Practice Center -LA - eng -PT - Review -PT - Book -PL - Rockville (MD) -EDAT- 2006/10/03 00:00 -CRDT- 2006/10/03 00:00 -AID - NBK263429 [bookaccession] - -PMID- 24074752 -OWN - NLM -STAT- MEDLINE -DCOM- 20140514 -LR - 20220409 -IS - 2046-4924 (Electronic) -IS - 1366-5278 (Print) -IS - 1366-5278 (Linking) -VI - 17 -IP - 43 -DP - 2013 Sep -TI - Aspirin for prophylactic use in the primary prevention of cardiovascular disease - and cancer: a systematic review and overview of reviews. -PG - 1-253 -LID - 10.3310/hta17430 [doi] -AB - BACKGROUND: Prophylactic aspirin has been considered to be beneficial in reducing - the risks of heart disease and cancer. However, potential benefits must be - balanced against the possible harm from side effects, such as bleeding and - gastrointestinal (GI) symptoms. It is particularly important to know the risk of - side effects when aspirin is used as primary prevention--that is when used by - people as yet free of, but at risk of developing, cardiovascular disease (CVD) or - cancer. In this report we aim to identify and re-analyse randomised controlled - trials (RCTs), systematic reviews and meta-analyses to summarise the current - scientific evidence with a focus on possible harms of prophylactic aspirin in - primary prevention of CVD and cancer. OBJECTIVES: To identify RCTs, systematic - reviews and meta-analyses of RCTs of the prophylactic use of aspirin in primary - prevention of CVD or cancer. To undertake a quality assessment of identified - systematic reviews and meta-analyses using meta-analysis to investigate - study-level effects on estimates of benefits and risks of adverse events; - cumulative meta-analysis; exploratory multivariable meta-regression; and to - quantify relative and absolute risks and benefits. METHODS: We identified RCTs, - meta-analyses and systematic reviews, and searched electronic bibliographic - databases (from 2008 September 2012) including MEDLINE, Cochrane Central Register - of Controlled Trials, Database of Abstracts of Reviews of Effects, NHS Centre for - Reviews and Dissemination, and Science Citation Index. We limited searches to - publications since 2008, based on timing of the most recent comprehensive - systematic reviews. RESULTS: In total, 2572 potentially relevant papers were - identified and 27 met the inclusion criteria. Benefits of aspirin ranged from 6% - reduction in relative risk (RR) for all-cause mortality [RR 0.94, 95% confidence - interval (CI) 0.88 to 1.00] and 10% reduction in major cardiovascular events - (MCEs) (RR 0.90, 95% CI 0.85 to 0.96) to a reduction in total coronary heart - disease (CHD) of 15% (RR 0.85, 95% CI 0.69 to 1.06). Reported pooled odds ratios - (ORs) for total cancer mortality ranged between 0.76 (95% CI 0.66 to 0.88) and - 0.93 (95% CI 0.84 to 1.03). Inclusion of the Women's Health Study changed the - estimated OR to 0.82 (95% CI 0.69 to 0.97). Aspirin reduced reported colorectal - cancer (CRC) incidence (OR 0.66, 95% CI 0.90 to 1.02). However, including studies - in which aspirin was given every other day raised the OR to 0.91 (95% CI 0.74 to - 1.11). Reported cancer benefits appeared approximately 5 years from start of - treatment. Calculation of absolute effects per 100,000 patient-years of follow-up - showed reductions ranging from 33 to 46 deaths (all-cause mortality), 60-84 MCEs - and 47-64 incidents of CHD and a possible avoidance of 34 deaths from CRC. - Reported increased RRs of adverse events from aspirin use were 37% for GI - bleeding (RR 1.37, 95% CI 1.15 to 1.62), between 54% (RR 1.54, 95% CI 1.30 to - 1.82) and 62% (RR 1.62, 95% CI 1.31 to 2.00) for major bleeds, and between 32% - (RR 1.32, 95% CI 1.00 to 1.74) and 38% (RR 1.38, 95% CI 1.01 to 1.82) for - haemorrhagic stroke. Pooled estimates of increased RR for bleeding remained - stable across trials conducted over several decades. Estimates of absolute rates - of harm from aspirin use, per 100,000 patient-years of follow-up, were 99-178 for - non-trivial bleeds, 46-49 for major bleeds, 68-117 for GI bleeds and 8-10 for - haemorrhagic stroke. Meta-analyses aimed at judging risk of bleed according to - sex and in individuals with diabetes were insufficiently powered for firm - conclusions to be drawn. LIMITATIONS: Searches were date limited to 2008 because - of the intense interest that this subject has generated and the cataloguing of - all primary research in so many previous systematic reviews. A further limitation - was our potential over-reliance on study-level systematic reviews in which the - person-years of follow-up were not accurately ascertainable. However, estimates - of number of events averted or incurred through aspirin use calculated from data - in study-level meta-analyses did not differ substantially from estimates based on - individual patient data-level meta-analyses, for which person-years of follow-up - were more accurate (although based on less-than-complete assemblies of currently - available primary studies). CONCLUSIONS: We have found that there is a fine - balance between benefits and risks from regular aspirin use in primary prevention - of CVD. Effects on cancer prevention have a long lead time and are at present - reliant on post hoc analyses. All absolute effects are relatively small compared - with the burden of these diseases. Several potentially relevant ongoing trials - will be completed between 2013 and 2019, which may clarify the extent of benefit - of aspirin in reducing cancer incidence and mortality. Future research - considerations include expanding the use of IPD meta-analysis of RCTs by pooling - data from available studies and investigating the impact of different dose - regimens on cardiovascular and cancer outcomes. FUNDING: The National Institute - for Health Research Health Technology Assessment programme. -FAU - Sutcliffe, P -AU - Sutcliffe P -AD - Warwick Evidence, Warwick Medical School, University of Warwick, Coventry, UK. -FAU - Connock, M -AU - Connock M -FAU - Gurung, T -AU - Gurung T -FAU - Freeman, K -AU - Freeman K -FAU - Johnson, S -AU - Johnson S -FAU - Kandala, N-B -AU - Kandala NB -FAU - Grove, A -AU - Grove A -FAU - Gurung, B -AU - Gurung B -FAU - Morrow, S -AU - Morrow S -FAU - Clarke, A -AU - Clarke A -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -PT - Systematic Review -PL - England -TA - Health Technol Assess -JT - Health technology assessment (Winchester, England) -JID - 9706284 -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Adult -MH - Aged -MH - Aspirin/*adverse effects/*therapeutic use -MH - Cardiovascular Diseases/mortality/*prevention & control -MH - Colorectal Neoplasms/mortality/prevention & control -MH - Confidence Intervals -MH - Female -MH - Gastrointestinal Hemorrhage/*chemically induced/epidemiology -MH - Humans -MH - Incidence -MH - Male -MH - Middle Aged -MH - Neoplasms/mortality/*prevention & control -MH - Odds Ratio -MH - Primary Prevention/*methods -MH - Prognosis -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - Survival Analysis -MH - United States -PMC - PMC4781046 -EDAT- 2013/10/01 06:00 -MHDA- 2014/05/16 06:00 -PMCR- 2016/03/07 -CRDT- 2013/10/01 06:00 -PHST- 2013/10/01 06:00 [entrez] -PHST- 2013/10/01 06:00 [pubmed] -PHST- 2014/05/16 06:00 [medline] -PHST- 2016/03/07 00:00 [pmc-release] -AID - 10.3310/hta17430 [doi] -PST - ppublish -SO - Health Technol Assess. 2013 Sep;17(43):1-253. doi: 10.3310/hta17430. - -PMID- 19900653 -OWN - NLM -STAT- MEDLINE -DCOM- 20100126 -LR - 20250623 -IS - 1532-8511 (Electronic) -IS - 1052-3057 (Linking) -VI - 18 -IP - 6 -DP - 2009 Nov-Dec -TI - Stroke prevention by cilostazol in patients with atherothrombosis: meta-analysis - of placebo-controlled randomized trials. -PG - 482-90 -LID - 10.1016/j.jstrokecerebrovasdis.2009.07.010 [doi] -AB - BACKGROUND: Cilostazol is an antiplatelet agent that inhibits phosphodiesterase - III in platelets and vascular endothelium. Previous randomized controlled trials - of cilostazol for prevention of cerebrovascular events have garnered mixed - results. We performed a systematic review and meta-analysis of the randomized - clinical trials in patients with atherothrombotic diseases to determine the - effects of cilostazol on cerebrovascular, cardiac, and all vascular events, and - on all major hemorrhagic events. METHODS: Relevant trials were identified by - searching MEDLINE, EMBASE, and the Cochrane Controlled Trial Registry for titles - and abstracts. Data from 12 randomized controlled trials, involving 5674 - patients, were analyzed for end points of cerebrovascular, cardiac, and major - bleeding events. Searching, determination of eligibility, data extraction, and - meta-analyses were conducted by multiple independent investigators. RESULTS: Data - were available in 3782, 1187, and 705 patients with peripheral arterial disease, - cerebrovascular disease, and coronary stenting, respectively. Incidence of total - vascular events was significantly lower in the cilostazol group compared with the - placebo group (relative risk [RR], 0.86; 95% confidence interval [CI], 0.74-0.99; - P=.038). This was particularly influenced by a significant decrease of incidence - of cerebrovascular events in the cilostazol group (RR, 0.58; 95% CI, 0.43-0.78; P - < .001). There was no significant intergroup difference in incidence of cardiac - events (RR, 0.99; 95% CI, 0.83-1.17; P=.908) and serious bleeding complications - (RR, 1.00; 95% CI, 0.66-1.51; P=.996). CONCLUSIONS: This first meta-analysis of - cilostazol in patients with atherothrombosis demonstrated a significant risk - reduction for cerebrovascular events, with no associated increase of bleeding - risk. -FAU - Uchiyama, Shinichiro -AU - Uchiyama S -AD - Department of Neurology, Tokyo Women's Medical University School of Medicine, - Shinjuku-ku, Tokyo, Japan. suchiyam@nij.twmu.ac.jp -FAU - Demaerschalk, Bart M -AU - Demaerschalk BM -FAU - Goto, Shinya -AU - Goto S -FAU - Shinohara, Yukito -AU - Shinohara Y -FAU - Gotoh, Fumio -AU - Gotoh F -FAU - Stone, William M -AU - Stone WM -FAU - Money, Samuel R -AU - Money SR -FAU - Kwon, Sun Uck -AU - Kwon SU -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - United States -TA - J Stroke Cerebrovasc Dis -JT - Journal of stroke and cerebrovascular diseases : the official journal of National - Stroke Association -JID - 9111633 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Tetrazoles) -RN - N7Z035406B (Cilostazol) -SB - IM -MH - Aged -MH - Atherosclerosis/complications/*drug therapy/mortality -MH - Cilostazol -MH - Evidence-Based Medicine -MH - Female -MH - Heart Diseases/etiology/prevention & control -MH - Hemorrhage/chemically induced -MH - Humans -MH - Male -MH - Middle Aged -MH - Platelet Aggregation Inhibitors/adverse effects/*therapeutic use -MH - Randomized Controlled Trials as Topic -MH - Risk Assessment -MH - Stroke/etiology/mortality/*prevention & control -MH - Tetrazoles/adverse effects/*therapeutic use -MH - Thrombosis/complications/*drug therapy/mortality -MH - Treatment Outcome -RF - 34 -EDAT- 2009/11/11 06:00 -MHDA- 2010/01/27 06:00 -CRDT- 2009/11/11 06:00 -PHST- 2009/06/17 00:00 [received] -PHST- 2009/07/14 00:00 [accepted] -PHST- 2009/11/11 06:00 [entrez] -PHST- 2009/11/11 06:00 [pubmed] -PHST- 2010/01/27 06:00 [medline] -AID - S1052-3057(09)00154-2 [pii] -AID - 10.1016/j.jstrokecerebrovasdis.2009.07.010 [doi] -PST - ppublish -SO - J Stroke Cerebrovasc Dis. 2009 Nov-Dec;18(6):482-90. doi: - 10.1016/j.jstrokecerebrovasdis.2009.07.010. - -PMID- 17764210 -OWN - NLM -STAT- MEDLINE -DCOM- 20090106 -LR - 20250623 -IS - 1530-4396 (Print) -IS - 1530-4396 (Linking) -IP - 142 -DP - 2006 Sep -TI - Testing for BNP and NT-proBNP in the diagnosis and prognosis of heart failure. -PG - 1-147 -AB - OBJECTIVES: The purpose of this systematic review was to evaluate BNP and - NT-proBNP to: (a) identify determinants, (b) establish their diagnostic - performance in heart failure (HF) patients, (c) determine their predictive - ability with respect to mortality and other cardiac endpoints, and (d) determine - their value in monitoring HF treatment. DATA SOURCES: MEDLINE, EMBASE, CINAHL, - Cochrane Central, and AMED from 1989 to February 2005 were searched for primary - studies. REVIEW METHODS: Standard systematic review methodology, including - meta-analysis, was employed. All study designs were included. Eligibility - criteria included English-only studies and restricted the number of test methods - to maximize generalizability. Outcomes for prognosis were limited to mortality - and specific cardiac events. Further specific criteria were developed for each - research question. RESULTS: Determinants: There were 103 determinants identified - including age, gender, disease, treatment, as well as biochemical and - physiological measures. Few studies reported independent associations and of - those that did age, female gender and creatinine levels were positively - associated with BNP and NT-proBNP. DIAGNOSIS: Pooled sensitivity and specificity - values were 94 and 66 percent for BNP and 92 and 65 percent for NT-proBNP; there - was minimal difference among settings (emergency, specialized clinics, and - primary care). B-type natriuretic peptides also added independent diagnostic - information above traditional measures for HF. PROGNOSIS: Both BNP and NT-proBNP - were found to be independent predictors of mortality and other cardiac composite - endpoints in patients with risk of coronary artery disease (CAD) (risk estimate - range = 1.10 to 5.40), diagnosed CAD (risk estimate range = 1.50 to 3.00), and - diagnosed HF patients (risk estimate range = 2.11 to 9.35). With respect to - screening, the AUC values (range = 0.57 to 0.88) suggested poor performance. - Monitoring Treatment: Studies showed therapy reduced BNP and NT-proBNP, however, - relationship to outcome was limited and not consistent. CONCLUSIONS: - Determinants: The importance of the identified determinants for clinical use is - not clear. DIAGNOSIS: In all settings both BNP and NT-proBNP show good diagnostic - properties as a rule out test for HF. PROGNOSIS: BNP and NT-proBNP are consistent - independent predictors of mortality and other cardiac composite endpoints for - populations with risk of CAD, diagnosed CAD, and diagnosed HF. There is - insufficient evidence to determine the value of B-type natriuretic peptides for - screening of HF. Monitoring Treatment: There is insufficient evidence to - demonstrate that BNP and NT-proBNP levels show change in response to therapies to - manage stable chronic HF patients. -FAU - Balion, C -AU - Balion C -FAU - Santaguida, P L -AU - Santaguida PL -FAU - Hill, S -AU - Hill S -FAU - Worster, A -AU - Worster A -FAU - McQueen, M -AU - McQueen M -FAU - Oremus, M -AU - Oremus M -FAU - McKelvie, R -AU - McKelvie R -FAU - Booker, L -AU - Booker L -FAU - Fagbemi, J -AU - Fagbemi J -FAU - Reichert, S -AU - Reichert S -FAU - Raina, P -AU - Raina P -LA - eng -PT - Journal Article -PT - Systematic Review -PL - United States -TA - Evid Rep Technol Assess (Full Rep) -JT - Evidence report/technology assessment -JID - 101082681 -RN - 0 (Peptide Fragments) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - 85637-73-6 (Atrial Natriuretic Factor) -SB - IM -MH - Age Factors -MH - Atrial Natriuretic Factor/*blood -MH - Female -MH - Heart Failure/*diagnosis -MH - Humans -MH - Male -MH - Natriuretic Peptide, Brain/*blood -MH - Peptide Fragments/*blood -MH - Prognosis -MH - Sex Factors -PMC - PMC4781047 -EDAT- 2007/09/04 09:00 -MHDA- 2009/01/07 09:00 -PMCR- 2016/03/07 -CRDT- 2007/09/04 09:00 -PHST- 2007/09/04 09:00 [pubmed] -PHST- 2009/01/07 09:00 [medline] -PHST- 2007/09/04 09:00 [entrez] -PHST- 2016/03/07 00:00 [pmc-release] -PST - ppublish -SO - Evid Rep Technol Assess (Full Rep). 2006 Sep;(142):1-147. - -PMID- 22963444 -OWN - NLM -STAT- MEDLINE -DCOM- 20121121 -LR - 20220409 -IS - 1470-8736 (Electronic) -IS - 0143-5221 (Linking) -VI - 124 -IP - 1 -DP - 2013 Jan -TI - Cardioprotection against ischaemia/reperfusion by vitamins C and E plus n-3 fatty - acids: molecular mechanisms and potential clinical applications. -PG - 1-15 -LID - 10.1042/CS20110663 [doi] -AB - The role of oxidative stress in ischaemic heart disease has been thoroughly - investigated in humans. Increased levels of ROS (reactive oxygen species) and RNS - (reactive nitrogen species) have been demonstrated during ischaemia and - post-ischaemic reperfusion in humans. Depending on their concentrations, these - reactive species can act either as benevolent molecules that promote cell - survival (at low-to-moderate concentrations) or can induce irreversible cellular - damage and death (at high concentrations). Although high ROS levels can induce - NF-κB (nuclear factor κB) activation, inflammation, apoptosis or necrosis, - low-to-moderate levels can enhance the antioxidant response, via Nrf2 (nuclear - factor-erythroid 2-related factor 2) activation. However, a clear definition of - these concentration thresholds remains to be established. Although a number of - experimental studies have demonstrated that oxidative stress plays a major role - in heart ischaemia/reperfusion pathophysiology, controlled clinical trials have - failed to prove the efficacy of antioxidants in acute or long-term treatments of - ischaemic heart disease. Oral doses of vitamin C are not sufficient to promote - ROS scavenging and only down-regulate their production via NADPH oxidase, a - biological effect shared by vitamin E to abrogate oxidative stress. However, - infusion of vitamin C at doses high enough to achieve plasma levels of 10 mmol/l - should prevent superoxide production and the pathophysiological cascade of - deleterious heart effects. In turn, n-3 PUFA (polyunsaturated fatty acid) - exposure leads to enhanced activity of antioxidant enzymes. In the present - review, we present evidence to support the molecular basis for a novel - pharmacological strategy using these antioxidant vitamins plus n-3 PUFAs for - cardioprotection in clinical settings, such as post-operative atrial - fibrillation, percutaneous coronary intervention following acute myocardial - infarction and other events that are associated with ischaemia/reperfusion. -FAU - Rodrigo, Ramón -AU - Rodrigo R -AD - Molecular and Clinical Pharmacology Program, Institute of Biomedical Sciences, - Faculty of Medicine, University of Chile, Santiago, Chile. rrodrigo@med.uchile.cl -FAU - Prieto, Juan C -AU - Prieto JC -FAU - Castillo, Rodrigo -AU - Castillo R -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Clin Sci (Lond) -JT - Clinical science (London, England : 1979) -JID - 7905731 -RN - 0 (Cardiotonic Agents) -RN - 0 (Fatty Acids, Omega-3) -RN - 0 (Reactive Oxygen Species) -RN - 1406-18-4 (Vitamin E) -RN - PQ6CK8PD0R (Ascorbic Acid) -SB - IM -MH - Apoptosis/drug effects/physiology -MH - Ascorbic Acid/blood/*metabolism/therapeutic use -MH - Cardiotonic Agents/*metabolism/therapeutic use -MH - Fatty Acids, Omega-3/*metabolism/therapeutic use -MH - Humans -MH - *Models, Biological -MH - Oxidative Stress/*drug effects -MH - Reactive Oxygen Species/*metabolism -MH - Reperfusion Injury/physiopathology/*prevention & control -MH - Vitamin E/*metabolism/therapeutic use -EDAT- 2012/09/12 06:00 -MHDA- 2012/12/10 06:00 -CRDT- 2012/09/12 06:00 -PHST- 2012/09/12 06:00 [entrez] -PHST- 2012/09/12 06:00 [pubmed] -PHST- 2012/12/10 06:00 [medline] -AID - CS20110663 [pii] -AID - 10.1042/CS20110663 [doi] -PST - ppublish -SO - Clin Sci (Lond). 2013 Jan;124(1):1-15. doi: 10.1042/CS20110663. - -PMID- 16999232 -OWN - NLM -STAT- MEDLINE -DCOM- 20070524 -LR - 20191110 -IS - 0171-2004 (Print) -IS - 0171-2004 (Linking) -IP - 176 Pt 2 -DP - 2006 -TI - Gene therapy: role in myocardial protection. -PG - 335-50 -AB - Heart failure associated with coronary artery disease is a major cause of - morbidity and mortality. Recent developments in the understanding of the - molecular mechanisms of heart failure have led to the identification of novel - therapeutic targets which, combined with the availability of efficient gene - delivery vectors, offer the opportunity for the design of gene therapies for - protection of the myocardium. Viral-based therapies have been developed to treat - polygenic and complex diseases such as myocardial ischaemia, hypertension, - atherosclerosis and restenosis. Some of these experimental therapies are now - undergoing clinical evaluation in patients with cardiovascular diseases. In this - review we will focus on the latest advances in the field of gene therapy for - treatment of heart failure and their clinical application. -FAU - Pachori, A S -AU - Pachori AS -AD - Department of Medicine, Division of Cardiology, Duke University Medical Center, - Durham, NC 27701, USA. alok.pachori@duke.edu -FAU - Melo, L G -AU - Melo LG -FAU - Dzau, V J -AU - Dzau VJ -LA - eng -PT - Journal Article -PT - Review -PL - Germany -TA - Handb Exp Pharmacol -JT - Handbook of experimental pharmacology -JID - 7902231 -RN - 0 (DNA, Antisense) -RN - 0 (Receptor, Angiotensin, Type 1) -RN - 0 (VEGFA protein, human) -RN - 0 (Vascular Endothelial Growth Factor A) -RN - EC 1.14.14.18 (Heme Oxygenase-1) -SB - IM -MH - Animals -MH - Cardiomegaly/metabolism -MH - DNA, Antisense/genetics/metabolism -MH - Gene Transfer Techniques -MH - Genetic Therapy/*trends -MH - Genetic Vectors -MH - Heme Oxygenase-1/biosynthesis/genetics -MH - Humans -MH - Myocardial Ischemia/etiology/metabolism/*prevention & control -MH - Myocardial Reperfusion Injury/etiology/metabolism/*prevention & control -MH - Randomized Controlled Trials as Topic -MH - Receptor, Angiotensin, Type 1/genetics/metabolism -MH - Vascular Endothelial Growth Factor A/biosynthesis/genetics -RF - 61 -EDAT- 2006/09/27 09:00 -MHDA- 2007/05/26 09:00 -CRDT- 2006/09/27 09:00 -PHST- 2006/09/27 09:00 [pubmed] -PHST- 2007/05/26 09:00 [medline] -PHST- 2006/09/27 09:00 [entrez] -AID - 10.1007/3-540-36028-x_11 [doi] -PST - ppublish -SO - Handb Exp Pharmacol. 2006;(176 Pt 2):335-50. doi: 10.1007/3-540-36028-x_11. - -PMID- 21864283 -OWN - NLM -STAT- MEDLINE -DCOM- 20120227 -LR - 20220426 -IS - 1875-533X (Electronic) -IS - 0929-8673 (Linking) -VI - 18 -IP - 29 -DP - 2011 -TI - Phytosterols: perspectives in human nutrition and clinical therapy. -PG - 4557-67 -AB - Phytosterols (PSs) are a group of plant derived steroid alcohols, with wide - occurrence in vegetables and fruits. They are integral components of plant cell - membranes, having stabilizing effects on phospholipids bilayer, just like - cholesterol in animal cell membranes. Structural resemblance of PSs with - cholesterol enables them to displace low-density lipoprotein (LDL) cholesterol in - the human intestine. Protective effects of PSs against cardiovascular diseases - (CVDs), colon and breast cancer developments have been widely documented. Several - reports have been published on the potential dietary intake of common PSs, such - as β-sitosterol, stigmasterol and campesterol, and their safety concerns. Ability - of PSs to reduce cholesterol levels and risks associated with heart problems has - made them a class of favorite food supplements. Nowadays functional foods - supplemented with PSs have become an alternative and healthy tool to lower - LDL-cholesterol levels in a natural way. However, excessive use of PSs has been - observed to develop premature coronary artery disease in phytosterolemic - patients, high risk of atherosclerotic CVDs, myocardial infarction and even - impaired endothelial functions. This manuscript will highlight the recent - developments in PSs with particular focus on their role as dietary supplements - and in treatment of various heart- and cholesterol-related ailments. Recently - explored side effects of PSs will also be discussed. -FAU - Choudhary, S P -AU - Choudhary SP -AD - Department of Botany, University of Jammu, Jammu 180006, India. -FAU - Tran, L S -AU - Tran LS -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Anticholesteremic Agents) -RN - 0 (Antineoplastic Agents, Phytogenic) -RN - 0 (Immunologic Factors) -RN - 0 (Phytosterols) -SB - IM -MH - Animals -MH - Anti-Inflammatory Agents/metabolism/pharmacology/therapeutic use -MH - Anticholesteremic Agents/metabolism/pharmacology/therapeutic use -MH - Antineoplastic Agents, Phytogenic/metabolism/pharmacology/therapeutic use -MH - Diabetes Mellitus/diet therapy/drug therapy -MH - *Dietary Supplements -MH - Humans -MH - Immunologic Factors/metabolism/pharmacology/therapeutic use -MH - Neoplasms/diet therapy/drug therapy -MH - Phytosterols/*metabolism/pharmacology/*therapeutic use -MH - Plants/*metabolism -EDAT- 2011/08/26 06:00 -MHDA- 2012/03/01 06:00 -CRDT- 2011/08/26 06:00 -PHST- 2011/06/18 00:00 [received] -PHST- 2011/08/01 00:00 [revised] -PHST- 2011/08/03 00:00 [accepted] -PHST- 2011/08/26 06:00 [entrez] -PHST- 2011/08/26 06:00 [pubmed] -PHST- 2012/03/01 06:00 [medline] -AID - BSP/CMC/E-Pub/2011/ 340 [pii] -AID - 10.2174/092986711797287593 [doi] -PST - ppublish -SO - Curr Med Chem. 2011;18(29):4557-67. doi: 10.2174/092986711797287593. - -PMID- 20600148 -OWN - NLM -STAT- MEDLINE -DCOM- 20100910 -LR - 20250529 -IS - 1879-0631 (Electronic) -IS - 0024-3205 (Print) -IS - 0024-3205 (Linking) -VI - 87 -IP - 9-10 -DP - 2010 Aug 28 -TI - Oxygen and oxygenation in stem-cell therapy for myocardial infarction. -PG - 269-74 -LID - 10.1016/j.lfs.2010.06.013 [doi] -AB - Myocardial infarction (MI) is caused by deprivation of oxygen and nutrients to - the cardiac tissue due to blockade of coronary artery. It is a major contributor - to chronic heart disease, a leading cause of mortality in the modern world. - Oxygen is required to meet the constant energy demands for heart contractility, - and also plays an important role in the regulation of heart function. However, - reoxygenation of the ischemic myocardium upon restoration of blood flow may lead - to further injury. Controlled oxygen delivery during reperfusion has been - advocated to prevent this consequence. Monitoring the myocardial oxygen - concentration would play a vital role in understanding the pathological changes - in the ischemic heart following myocardial infarction. During the last two - decades, several new techniques have become available to monitor myocardial - oxygen concentration in vivo. Electron paramagnetic resonance (EPR) oximetry - would appear to be the most promising and reliable of these techniques. EPR - utilizes crystalline probes which yield a single sharp line, the width of which - is highly sensitive to oxygen tension. Decreased oxygen tension results in a - sharpening of the EPR spectrum, while an increase results in widening. In our - recent studies, we have used EPR oximetry as a valuable tool to monitor - myocardial oxygenation for several applications like ischemia-reperfusion injury, - stem-cell therapy and hyperbaric oxygen therapy. The results obtained from these - studies have demonstrated the importance of tissue oxygen in the application of - stem-cell therapy to treat ischemic heart tissues. These results have been - summarized in this review article. -CI - Copyright (c) 2010 Elsevier Inc. All rights reserved. -FAU - Khan, Mahmood -AU - Khan M -AD - Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, - Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, - USA. -FAU - Kwiatkowski, Pawel -AU - Kwiatkowski P -FAU - Rivera, Brian K -AU - Rivera BK -FAU - Kuppusamy, Periannan -AU - Kuppusamy P -LA - eng -GR - R01 EB004031/EB/NIBIB NIH HHS/United States -GR - EB006153/EB/NIBIB NIH HHS/United States -GR - UL1 RR025755/RR/NCRR NIH HHS/United States -GR - R01 EB006153/EB/NIBIB NIH HHS/United States -GR - EB004031/EB/NIBIB NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100628 -PL - Netherlands -TA - Life Sci -JT - Life sciences -JID - 0375521 -SB - IM -MH - Animals -MH - Electron Spin Resonance Spectroscopy -MH - Humans -MH - *Hyperbaric Oxygenation -MH - Myocardial Infarction/metabolism/pathology/surgery/*therapy -MH - Myocardial Reperfusion Injury/metabolism/prevention & control -MH - Myocardium/*metabolism/pathology -MH - Oximetry/methods -MH - Oxygen Consumption/*physiology -MH - *Stem Cell Transplantation -PMC - PMC3114881 -MID - NIHMS232750 -EDAT- 2010/07/06 06:00 -MHDA- 2010/09/11 06:00 -PMCR- 2011/08/28 -CRDT- 2010/07/06 06:00 -PHST- 2010/05/07 00:00 [received] -PHST- 2010/06/09 00:00 [revised] -PHST- 2010/06/15 00:00 [accepted] -PHST- 2010/07/06 06:00 [entrez] -PHST- 2010/07/06 06:00 [pubmed] -PHST- 2010/09/11 06:00 [medline] -PHST- 2011/08/28 00:00 [pmc-release] -AID - S0024-3205(10)00265-1 [pii] -AID - 10.1016/j.lfs.2010.06.013 [doi] -PST - ppublish -SO - Life Sci. 2010 Aug 28;87(9-10):269-74. doi: 10.1016/j.lfs.2010.06.013. Epub 2010 - Jun 28. - -PMID- 17446035 -OWN - NLM -STAT- MEDLINE -DCOM- 20070731 -LR - 20161209 -IS - 0755-4982 (Print) -IS - 0755-4982 (Linking) -VI - 36 -IP - 6 Pt 2 -DP - 2007 Jun -TI - [Arrhythmias in sleep apnea syndrome]. -PG - 1012-5 -AB - Arrhythmias are more frequent in patients with sleep apnea syndrome. Bradycardias - predominate. In the absence of controlled studies, it is difficult to link - arrhythmias to sleep apnea syndrome or to the disease accompanying it (coronary - disease, hypertension, etc.). Continuous positive airway pressure (CPAP) reduces - arrhythmias significantly. -FAU - Clementy, Jacques -AU - Clementy J -AD - Service de cardiologie médicale E, Hôpital cardiologique du Haut Lévêque, Pessac - Cedex, France. jacques.clementy@pu.u-bordeaux2.fr -FAU - Bordachar, Pierre -AU - Bordachar P -FAU - Reuter, Sylvain -AU - Reuter S -FAU - Deplagne, Antoine -AU - Deplagne A -FAU - Bordier, Philippe -AU - Bordier P -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Troubles du rythme cardiaque dans le syndrome d'apnée du sommeil. -DEP - 20070418 -PL - France -TA - Presse Med -JT - Presse medicale (Paris, France : 1983) -JID - 8302490 -SB - IM -MH - Arrhythmias, Cardiac/*complications -MH - Continuous Positive Airway Pressure -MH - Humans -MH - Sleep Apnea Syndromes/*complications/therapy -RF - 12 -EDAT- 2007/04/21 09:00 -MHDA- 2007/08/01 09:00 -CRDT- 2007/04/21 09:00 -PHST- 2007/01/24 00:00 [received] -PHST- 2007/02/15 00:00 [accepted] -PHST- 2007/04/21 09:00 [pubmed] -PHST- 2007/08/01 09:00 [medline] -PHST- 2007/04/21 09:00 [entrez] -AID - S0755-4982(07)00247-3 [pii] -AID - 10.1016/j.lpm.2007.02.023 [doi] -PST - ppublish -SO - Presse Med. 2007 Jun;36(6 Pt 2):1012-5. doi: 10.1016/j.lpm.2007.02.023. Epub 2007 - Apr 18. - -PMID- 21208157 -OWN - NLM -STAT- MEDLINE -DCOM- 20110509 -LR - 20220317 -VI - 6 -IP - 1 -DP - 2011 Jan -TI - Levosimendan: from basic science to clinical trials. -PG - 9-15 -AB - Levosimendan is one of the documented pharmacological agents used in the - management and treatment of acute and chronic heart failure; it is a novel - inodilator agent which enhanced myocardial performance without changes in oxygen - consumption. The combination of positive inotropic and vasodilator effects of - levosimendan relates to its Ca(2+) - sensitizing and K(+) channels opening - effects. Levosimendan has been proposed, in the recent past, to be non-inferior - and may have some advantages to standard inotropes; further possible indications - for levosimendan have been described, in some observational studies, such as a - perioperative use, cardioprotection, cardiogenic shock, sepsis and right - ventricular dysfunction. The ability of levosimendan to improve myocardial - function without substantially increasing oxygen consumption may appear - paradoxical but is possible via improved efficacy not only with regard to the - effects on the contractile apparatus of the cardiomyocytes. The aim of this - review is to describe the pharmacological characteristics of levosimendan and its - clinical applications. The patent review data regarding the use of levosimendan - are also discussed in this review article. -FAU - Rognoni, Andrea -AU - Rognoni A -AD - Coronary Care Unit, Hospital Maggiore della Carità, Novara, Italy. -FAU - Lupi, Alessandro -AU - Lupi A -FAU - Lazzero, Maurizio -AU - Lazzero M -FAU - Bongo, Angelo S -AU - Bongo AS -FAU - Rognoni, Giorgio -AU - Rognoni G -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Recent Pat Cardiovasc Drug Discov -JT - Recent patents on cardiovascular drug discovery -JID - 101263805 -RN - 0 (Calcium Channels) -RN - 0 (Cardiovascular Agents) -RN - 0 (Hydrazones) -RN - 0 (Potassium Channels) -RN - 0 (Pyridazines) -RN - 349552KRHK (Simendan) -SB - IM -MH - Acute Disease -MH - Animals -MH - Calcium Channels/drug effects/metabolism -MH - Cardiovascular Agents/adverse effects/*therapeutic use -MH - Chronic Disease -MH - Evidence-Based Medicine -MH - Heart Failure/*drug therapy/metabolism/physiopathology -MH - Humans -MH - Hydrazones/adverse effects/*therapeutic use -MH - Myocardial Contraction/drug effects -MH - Myocardium/metabolism -MH - Oxygen Consumption -MH - Potassium Channels/drug effects/metabolism -MH - Pyridazines/adverse effects/*therapeutic use -MH - Simendan -MH - Translational Research, Biomedical -MH - Treatment Outcome -MH - Ventricular Function/drug effects -EDAT- 2011/01/07 06:00 -MHDA- 2011/05/10 06:00 -CRDT- 2011/01/07 06:00 -PHST- 2010/02/03 00:00 [received] -PHST- 2010/11/22 00:00 [accepted] -PHST- 2011/01/07 06:00 [entrez] -PHST- 2011/01/07 06:00 [pubmed] -PHST- 2011/05/10 06:00 [medline] -AID - BSP/PRC/EPUB/00020 [pii] -AID - 10.2174/157489011794578455 [doi] -PST - ppublish -SO - Recent Pat Cardiovasc Drug Discov. 2011 Jan;6(1):9-15. doi: - 10.2174/157489011794578455. - -PMID- 25834876 -STAT- Publisher -PB - Agency for Healthcare Research and Quality (US) -CTI - AHRQ Technology Assessments -DP - 2012 Jun -BTI - Systematic Review of ECG-based Signal Analysis Technologies for Evaluating - Patients With Acute Coronary Syndrome -AB - OBJECTIVES: To summarize the clinical and scientific evidence for commercially - available ECG-based signal analysis technologies used or proposed to be used to - evaluate patients at low to intermediate risk for coronary artery disease (CAD) - who have chest pain or other symptoms suggestive of acute coronary syndrome - (ACS). DATA SOURCES: Searches of gray literature sources, MEDLINE(®), EMBASE(®), - and the Cochrane Database of Systematic Reviews and Database of Abstracts of - Reviews of Effects. REVIEW METHODS: We conducted a systematic search of - English-language literature to identify published evidence for ECG-based - technologies that may improve the diagnosis of CAD and/or ACS through signal - analysis or other forms of advanced data transformation. For inclusion, a - technology had to be (1) a physical device that obtains and interprets - information about the electrical activity of the heart in ways that are different - from the standard 12-lead ECG, (2) cleared for marketing by the U.S. Food and - Drug Administration (FDA) and commercially available in the United States with - feasible implementation, (3) tested in patients at low to intermediate risk for - CAD who have a clinical presentation consistent with ACS, and (4) reported in a - peer-reviewed, published study that reports performance characteristics, effects - on diagnostic or treatment decisions, or effects on patient outcomes. Reviewers - worked in pairs to extract data, assess applicability, and evaluate the quality - of each study. We used a bivariate random-effects generalized linear regression - model to compute summary estimates of sensitivity and specificity. RESULTS: We - identified eight commercially available, FDA-cleared ECG-based devices proposed - for use to diagnose CAD or detect ACS. Of these, published evidence meeting - inclusion criteria was available for only two devices: PRIME ECG and LP 3000. - PRIME ECG test performance was reported in 10 studies. Meta-analysis of eight of - these studies determined a 68.4 percent sensitivity (95% CI, 35.1 to 89.7) and - 91.4 percent specificity (CI, 83.6 to 95.7) for the PRIME ECG in detecting MI - (with all but one study using elevated cardiac biomarkers as the reference - standard) compared with 40.5 percent sensitivity (CI, 19.6 to 65.5) and 95.0 - percent specificity (CI, 87.9 to 98.0) for the standard 12-lead ECG. Differences - in test performance between the PRIME ECG and 12-lead ECG are not statistically - significant as judged by the overlapping confidence intervals. A single study of - LP 3000 demonstrated that QRS prolongation on the signal-averaging ECG was - associated with a sensitivity and specificity of 70 percent and 89 percent, - respectively, compared with 56 percent and 89 percent for ST changes detected by - 12-lead ECG. The improved sensitivity of the signal-averaging ECG versus the - 12-lead ECG in that study was statistically significant (p<0.01). CONCLUSIONS: - Existing research is largely insufficient to confidently inform the appropriate - use of ECG-based signal analysis technologies in diagnosing CAD and/or ACS. - Further research is needed to better describe the performance characteristics of - these devices to determine in what circumstances, if any, these devices might - precede, replace, or add to the standard ECG in test strategies to identify - clinically significant CAD in the patient population of interest. To fully assess - the impact of these devices on diagnostic strategies for patients with chest - pain, test performance needs to be linked to clinically important outcomes - through modeling or longitudinal studies. -FAU - Coeytaux, Remy R -AU - Coeytaux RR -AD - Duke Evidence-based Practice Center -FAU - Leisy, Philip J -AU - Leisy PJ -AD - Duke Evidence-based Practice Center -FAU - Wagner, Galen S -AU - Wagner GS -AD - Duke Evidence-based Practice Center -FAU - McBroom, Amanda J -AU - McBroom AJ -AD - Duke Evidence-based Practice Center -FAU - Green, Cynthia L -AU - Green CL -AD - Duke Evidence-based Practice Center -FAU - Wing, Liz -AU - Wing L -AD - Duke Evidence-based Practice Center -FAU - Irvine, R Julian -AU - Irvine RJ -AD - Duke Evidence-based Practice Center -FAU - Sanders, Gillian D -AU - Sanders GD -AD - Duke Evidence-based Practice Center -LA - eng -PT - Review -PT - Book -PL - Rockville (MD) -EDAT- 2012/06/01 00:00 -CRDT- 2012/06/01 00:00 -AID - NBK280225 [bookaccession] - -PMID- 22734339 -OWN - NLM -STAT- MEDLINE -DCOM- 20120814 -LR - 20171116 -IS - 0019-4832 (Print) -IS - 0019-4832 (Linking) -VI - 63 -IP - 3 -DP - 2011 May-Jun -TI - Intensive statin therapy for Indians: Part-I. Benefits. -PG - 211-27 -AB - The underlying disorder in the vast majority of cases of cardiovascular disease - (CVD) is atherosclerosis, for which low-density lipoprotein cholesterol (LDL-C) - is recognized as the first and foremost risk factor. HMG-CoA reductase - inhibitors, popularly called statins, are highly effective and remarkably safe in - reducing LDL-C and non-HDL-C levels. Evidence from clinical trials have - demonstrated that statin therapy can reduce the risk of myocardial infarction - (MI), stroke, death, and the need for coronary artery revascularization - procedures (CARPs) by 25-50%, depending on the magnitude of LDL-C lowering - achieved. Benefits are seen in men and women, young and old, and in people with - and without diabetes or prior diagnosis of CVD. Clinical trials comparing - standard statin therapy to intensive statin therapy have clearly demonstrated - greater benefits in CVD risk reduction (including halting the progression and - even reversing coronary atherosclerosis) without any corresponding increase in - risk. Numerous outcome trials of intensive statin therapy using atorvastatin 80 - mg/d have demonstrated the safety and the benefits of lowering LDL-C to very low - levels. This led the USNCEP Guideline Committee to standardize 40 mg/dL as the - optimum LDL-C level, above which the CVD risk begins to rise. Recent studies have - shown intensive statin therapy can also lower CVD events even in low-risk - individuals with LDL-C <110 mg/dL. Because of the heightened risk of CVD in Asian - Indians, the LDL-C target is set at 30 mg/dL lower than that recommended by NCEP. - Accordingly, the LDL-C goal is < 70 mg/dL for Indians who have CVD, diabetes, - metabolic syndrome, or chronic kidney disease. Intensive statin therapy is often - required in these populations as well as others who require a > or = 50% - reduction in LDL-C. Broader acceptance of this lower LDL-C targets and its - implementation could reduce the CVD burden in the Indian population by 50% in the - next 25 years. Clinical trial data support an extremely favorable benefit-to-risk - ratio of intensive statin therapy with some but not all statins. Atorvastatin 80 - mg/d is 100 times safer than aspirin 81 mg/d and 10 times safer than diabetic - medications. Intensive statin therapy is more effective and safe compared to - intensive control of blood sugar or blood pressure in patients with diabetes. -FAU - Enas, Enas A -AU - Enas EA -AD - Coronary Artery Disease in Asian Indians (CADI) Research Foundation Lisle, IL - USA. cadiusa@msn.com -FAU - Pazhoor, Hancy Chennikkara -AU - Pazhoor HC -FAU - Kuruvila, Arun -AU - Kuruvila A -FAU - Vijayaraghavan, Krishnaswami -AU - Vijayaraghavan K -LA - eng -PT - Journal Article -PT - Review -PL - India -TA - Indian Heart J -JT - Indian heart journal -JID - 0374675 -RN - 0 (Apolipoproteins B) -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -SB - IM -MH - Apolipoproteins B/blood/drug effects -MH - Atherosclerosis/blood/*prevention & control -MH - Cardiovascular Diseases/blood/*prevention & control -MH - Cholesterol, LDL/blood/drug effects -MH - Clinical Trials as Topic -MH - Cost-Benefit Analysis -MH - Diabetes Complications/blood/prevention & control -MH - Female -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - India -MH - Kidney Failure, Chronic/blood/prevention & control -MH - Male -MH - Metabolic Syndrome/blood/prevention & control -MH - Peripheral Vascular Diseases/blood/prevention & control -MH - Primary Prevention -MH - Risk Factors -EDAT- 2012/06/28 06:00 -MHDA- 2012/08/15 06:00 -CRDT- 2012/06/28 06:00 -PHST- 2012/06/28 06:00 [entrez] -PHST- 2012/06/28 06:00 [pubmed] -PHST- 2012/08/15 06:00 [medline] -PST - ppublish -SO - Indian Heart J. 2011 May-Jun;63(3):211-27. - -PMID- 24423973 -OWN - NLM -STAT- MEDLINE -DCOM- 20140411 -LR - 20240805 -IS - 1555-7162 (Electronic) -IS - 0002-9343 (Linking) -VI - 127 -IP - 3 -DP - 2014 Mar -TI - All men with vasculogenic erectile dysfunction require a cardiovascular workup. -PG - 174-82 -LID - S0002-9343(13)00927-3 [pii] -LID - 10.1016/j.amjmed.2013.10.013 [doi] -AB - An association between erectile dysfunction and cardiovascular disease has long - been recognized, and studies suggest that erectile dysfunction is an independent - marker of cardiovascular disease risk. Therefore, assessment and management of - erectile dysfunction may help identify and reduce the risk of future - cardiovascular events, particularly in younger men. The initial erectile - dysfunction evaluation should distinguish between predominantly vasculogenic - erectile dysfunction and erectile dysfunction of other etiologies. For men - believed to have predominantly vasculogenic erectile dysfunction, we recommend - that initial cardiovascular risk stratification be based on the Framingham Risk - Score. Management of men with erectile dysfunction who are at low risk for - cardiovascular disease should focus on risk-factor control; men at high risk, - including those with cardiovascular symptoms, should be referred to a - cardiologist. Intermediate-risk men should undergo noninvasive evaluation for - subclinical atherosclerosis. A growing body of evidence supports the use of - emerging prognostic markers to further understand cardiovascular risk in men with - erectile dysfunction, but few markers have been prospectively evaluated in this - population. In conclusion, we support cardiovascular risk stratification and - risk-factor management in all men with vasculogenic erectile dysfunction. -CI - Copyright © 2014 Elsevier Inc. All rights reserved. -FAU - Miner, Martin -AU - Miner M -AD - Departments of Family Medicine and Urology, Miriam Hospital and Brown University, - Providence, RI. Electronic address: martin_miner@brown.edu. -FAU - Nehra, Ajay -AU - Nehra A -AD - Department of Urology, Rush University, Chicago, Ill. -FAU - Jackson, Graham -AU - Jackson G -AD - Guy's & St. Thomas Hospital, London, UK. -FAU - Bhasin, Shalender -AU - Bhasin S -AD - Department of Medicine, Section of Endocrinology, Diabetes, and Nutrition, Boston - University School of Medicine, Mass. -FAU - Billups, Kevin -AU - Billups K -AD - Department of Urologic Surgery, University of Minnesota, Minneapolis; The James - Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, Md. -FAU - Burnett, Arthur L -AU - Burnett AL -AD - The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, - Baltimore, Md. -FAU - Buvat, Jacques -AU - Buvat J -AD - Centre d'Etude et de Traitement de la Pathologie de l'Appareil Reproducteur et de - la Psychosomatique, Lille, France. -FAU - Carson, Culley -AU - Carson C -AD - Department of Surgery, Division of Urologic Surgery, University of North - Carolina, Chapel Hill. -FAU - Cunningham, Glenn -AU - Cunningham G -AD - Departments of Medicine, and Molecular & Cellular Biology, Baylor College of - Medicine and St. Luke's Episcopal Hospital, Houston, Tex. -FAU - Ganz, Peter -AU - Ganz P -AD - Division of Cardiology, San Francisco General Hospital and University of - California, San Francisco, Calif. -FAU - Goldstein, Irwin -AU - Goldstein I -AD - San Diego Sexual Medicine, Calif. -FAU - Guay, Andre -AU - Guay A -AD - Center For Sexual Function/Endocrinology, Lahey Clinic Medical Center, Peabody, - Mass, Tufts University School of Medicine, Boston, Mass. -FAU - Hackett, Geoff -AU - Hackett G -AD - Good Hope Hospital, Birmingham, UK. -FAU - Kloner, Robert A -AU - Kloner RA -AD - Heart Institute, Good Samaritan Hospital and Keck School of Medicine at - University of Southern California, Los Angeles. -FAU - Kostis, John B -AU - Kostis JB -AD - Cardiovascular Institute, UMDNJ-Robert Wood Johnson Medical School, New - Brunswick, NJ. -FAU - LaFlamme, K Elizabeth -AU - LaFlamme KE -AD - Complete Healthcare Communications, Inc., Chadds Ford, Pa. -FAU - Montorsi, Piero -AU - Montorsi P -AD - Centro Cardiologico Monzino, IRCCS, Institute of Cardiology University of Milan, - Italy. -FAU - Ramsey, Melinda -AU - Ramsey M -AD - Complete Healthcare Communications, Inc., Chadds Ford, Pa. -FAU - Rosen, Raymond -AU - Rosen R -AD - New England Research Institutes, Inc., Watertown, Mass. -FAU - Sadovsky, Richard -AU - Sadovsky R -AD - Department of Family Medicine, SUNY-Downstate Medical Center, Brooklyn, NY. -FAU - Seftel, Allen -AU - Seftel A -AD - Department of Urology, Cooper University Hospital, Camden, NJ. -FAU - Shabsigh, Ridwan -AU - Shabsigh R -AD - Division of Urology, Maimonides Medical Center, Brooklyn, NY, and College of - Physicians and Surgeons of Columbia University, New York, NY. -FAU - Vlachopoulos, Charalambos -AU - Vlachopoulos C -AD - 1st Department of Cardiology, Athens Medical School, Athens, Greece. -FAU - Wu, Frederick -AU - Wu F -AD - Andrology Research Unit, Developmental & Regenerative Biomedicine Research Group, - University of Manchester, Manchester Academic Health Science Centre, Manchester - Royal Infirmary, UK. -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20131101 -PL - United States -TA - Am J Med -JT - The American journal of medicine -JID - 0267200 -RN - 0 (Biomarkers) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Ankle Brachial Index -MH - Atherosclerosis/complications/diagnosis -MH - Biomarkers/blood -MH - Calcium/metabolism -MH - Cardiovascular Diseases/blood/*complications/*diagnosis/physiopathology -MH - Carotid Intima-Media Thickness -MH - Coronary Vessels/metabolism -MH - Endothelium, Vascular/physiopathology -MH - Humans -MH - Impotence, Vasculogenic/*etiology -MH - Male -MH - Risk Factors -OTO - NOTNLM -OT - Cardiovascular disease -OT - Erectile dysfunction -OT - Evaluation -EDAT- 2014/01/16 06:00 -MHDA- 2014/04/12 06:00 -CRDT- 2014/01/16 06:00 -PHST- 2013/04/17 00:00 [received] -PHST- 2013/10/15 00:00 [revised] -PHST- 2013/10/15 00:00 [accepted] -PHST- 2014/01/16 06:00 [entrez] -PHST- 2014/01/16 06:00 [pubmed] -PHST- 2014/04/12 06:00 [medline] -AID - S0002-9343(13)00927-3 [pii] -AID - 10.1016/j.amjmed.2013.10.013 [doi] -PST - ppublish -SO - Am J Med. 2014 Mar;127(3):174-82. doi: 10.1016/j.amjmed.2013.10.013. Epub 2013 - Nov 1. - -PMID- 20854971 -OWN - NLM -STAT- MEDLINE -DCOM- 20101026 -LR - 20100921 -IS - 1879-1913 (Electronic) -IS - 0002-9149 (Linking) -VI - 106 -IP - 7 -DP - 2010 Oct 1 -TI - The variant associations of aortic isthmic coarctation. -PG - 1038-41 -LID - 10.1016/j.amjcard.2010.04.046 [doi] -AB - The term "coarctation" necessarily calls attention to a specific morphologic - abnormality of the aortic isthmus. However, in this report, the author seeks to - dispel the simplistic notion that coarctation is best characterized by isthmic - obstruction, which is only 1 of an assemblage of abnormalities that include the - proximal paracoarctation aorta, the distal paracoarctation aorta, the ascending - aorta, the transverse aorta, the coronary arteries, the conduit arteries (radial, - brachial, and carotid), the retinal vascular bed, dissecting aneurysms, cerebral - aneurysms, vascular rings, systemic hypertension, and a decrease in left - ventricular interpapillary muscle distance. Some of these abnormalities are - secondary to the coarctation, such as collateral arteries and dissecting - aneurysms. Others frequently or invariably coexist but are not secondary, such as - bicuspid aortic valve and aneurysm of the circle of Willis. Still other - abnormalities are seemingly contradictory, such as aneurysmal dilatation of the - low-pressure distal paracoarctation aorta, while the high-pressure proximal - segment does not dilate significantly. In conclusion, coarctation should be - regarded as an assemblage of cardiovascular abnormalities rather than as isolated - obstruction of the aortic isthmus. -CI - Copyright © 2010 Elsevier Inc. All rights reserved. -FAU - Perloff, Joseph K -AU - Perloff JK -AD - Ahmanson/UCLA Adult Congenital Heart Disease Center, Los Angeles, California, - USA. josephperloff@earthlink.net -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Cardiol -JT - The American journal of cardiology -JID - 0207277 -SB - IM -MH - Aortic Coarctation/*complications/*pathology -MH - Humans -EDAT- 2010/09/22 06:00 -MHDA- 2010/10/27 06:00 -CRDT- 2010/09/22 06:00 -PHST- 2010/04/10 00:00 [received] -PHST- 2010/04/15 00:00 [revised] -PHST- 2010/04/15 00:00 [accepted] -PHST- 2010/09/22 06:00 [entrez] -PHST- 2010/09/22 06:00 [pubmed] -PHST- 2010/10/27 06:00 [medline] -AID - S0002-9149(10)01489-X [pii] -AID - 10.1016/j.amjcard.2010.04.046 [doi] -PST - ppublish -SO - Am J Cardiol. 2010 Oct 1;106(7):1038-41. doi: 10.1016/j.amjcard.2010.04.046. - -PMID- 18489845 -OWN - NLM -STAT- MEDLINE -DCOM- 20080825 -LR - 20211203 -IS - 1534-6242 (Electronic) -IS - 1523-3804 (Linking) -VI - 10 -IP - 3 -DP - 2008 Jun -TI - Genetics of premature myocardial infarction. -PG - 186-93 -AB - Common multigene disorders account for 80% of deaths in the world and all have - significant genetic predisposition. Coronary artery disease and myocardial - infarction (MI) account for more than 40% of these deaths. The genetic component - is due to multiple genes, each contributing only minimally to the phenotype. - Linkage analysis, which has been successful in identifying rare disorders that - cause MI, is not sensitive for multigene disorders. The recent candidate - case-control approach has been equally unsuccessful. Multigene disorders require - genome-wide association studies involving genotyping hundreds of thousands of DNA - markers in thousands of individuals with replication in independent populations. - Platforms with 500,000 and 1 million single nucleotide polymorphisms provide the - necessary high-throughput genotyping for genome-wide association. The first - confirmed common locus, 9p21, is independent of conventional risk factors. - Identifying the 9p21 gene will elucidate novel mechanisms responsible for MI. - Comprehensive prevention of MI based on individual genetic variants (personalized - medicine) is expected in the next decade. -FAU - Roberts, Robert -AU - Roberts R -AD - University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, K1Y 4W7, - Canada. rroberts@ottawaheart.ca -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Atheroscler Rep -JT - Current atherosclerosis reports -JID - 100897685 -RN - 0 (5-Lipoxygenase-Activating Proteins) -RN - 0 (ALOX5AP protein, human) -RN - 0 (Carrier Proteins) -RN - 0 (Guanine Nucleotide Exchange Factors) -RN - 0 (Lymphotoxin-alpha) -RN - 0 (Membrane Proteins) -RN - 0 (RNA, Antisense) -RN - EC 2.7.11.1 (KALRN protein, human) -RN - EC 2.7.11.1 (Protein Serine-Threonine Kinases) -SB - IM -MH - 5-Lipoxygenase-Activating Proteins -MH - Age of Onset -MH - Carrier Proteins/genetics -MH - Chromosomes, Human, Pair 9/genetics -MH - Genetic Linkage -MH - *Genetic Predisposition to Disease -MH - Genomics -MH - Guanine Nucleotide Exchange Factors/genetics -MH - Humans -MH - Hyperlipoproteinemia Type II/complications/genetics -MH - Lymphotoxin-alpha/genetics -MH - Membrane Proteins/genetics -MH - Multifactorial Inheritance -MH - Myocardial Infarction/*genetics -MH - Polymorphism, Single Nucleotide -MH - Protein Serine-Threonine Kinases/genetics -MH - RNA, Antisense -RF - 54 -EDAT- 2008/05/21 09:00 -MHDA- 2008/08/30 09:00 -CRDT- 2008/05/21 09:00 -PHST- 2008/05/21 09:00 [pubmed] -PHST- 2008/08/30 09:00 [medline] -PHST- 2008/05/21 09:00 [entrez] -AID - 10.1007/s11883-008-0030-2 [doi] -PST - ppublish -SO - Curr Atheroscler Rep. 2008 Jun;10(3):186-93. doi: 10.1007/s11883-008-0030-2. - -PMID- 16971976 -OWN - NLM -STAT- MEDLINE -DCOM- 20061019 -LR - 20190608 -IS - 0828-282X (Print) -IS - 1916-7075 (Electronic) -IS - 0828-282X (Linking) -VI - 22 -IP - 11 -DP - 2006 Sep -TI - Canadian Cardiovascular Society position statement--recommendations for the - diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease. -PG - 913-27 -AB - Since the last publication of the recommendations for the management and - treatment of dyslipidemia, new clinical trial data have emerged that support a - more vigorous approach to lipid lowering in specific patient groups. The decision - was made to update the lipid guidelines in collaboration with the Canadian - Cardiovascular Society. A systematic electronic search of medical literature for - original research consisting of blinded, randomized controlled trials was - performed. Meta-analyses of studies of the efficacy and safety of lipid-lowering - therapies, and of the predictive value of established and emerging risk factors - were also reviewed. All recommendations are evidence-based, and have been - reviewed in detail by primary and secondary review panels. Major changes include - a lower low-density lipoprotein cholesterol (LDL-C) treatment target (lower than - 2.0 mmol/L) for high-risk patients, a slightly higher intervention point for the - initiation of drug therapy in most low-risk individuals (LDL-C of 5.0 mmol/L or a - total cholesterol to high-density lipoprotein cholesterol ratio of 6.0) and - recommendations regarding additional investigations of potential use in the - further evaluation of coronary artery disease risk in subjects in the - moderate-risk category. -FAU - McPherson, Ruth -AU - McPherson R -AD - University of Ottawa Heart Institute, Ottawa, Canada. rmcpherson@ottawaheart.ca -FAU - Frohlich, Jiri -AU - Frohlich J -FAU - Fodor, George -AU - Fodor G -FAU - Genest, Jacques -AU - Genest J -FAU - Canadian Cardiovascular Society -AU - Canadian Cardiovascular Society -LA - eng -PT - Consensus Development Conference -PT - Journal Article -PT - Practice Guideline -PL - England -TA - Can J Cardiol -JT - The Canadian journal of cardiology -JID - 8510280 -SB - IM -EIN - Can J Cardiol. 2006 Oct;22(12):1077 -CIN - Can J Cardiol. 2007 May 1;23(6):481-2; author reply 483. doi: - 10.1016/s0828-282x(07)70793-6. PMID: 17549843 -MH - Canada -MH - Cardiology/*standards -MH - Cardiovascular Diseases/etiology/*prevention & control -MH - Humans -MH - Hyperlipidemias/complications/*diagnosis/*therapy -MH - Societies, Medical -PMC - PMC2570238 -EDAT- 2006/09/15 09:00 -MHDA- 2006/10/20 09:00 -PMCR- 2007/09/01 -CRDT- 2006/09/15 09:00 -PHST- 2006/09/15 09:00 [pubmed] -PHST- 2006/10/20 09:00 [medline] -PHST- 2006/09/15 09:00 [entrez] -PHST- 2007/09/01 00:00 [pmc-release] -AID - S0828-282X(06)70310-5 [pii] -AID - cjc220913 [pii] -AID - 10.1016/s0828-282x(06)70310-5 [doi] -PST - ppublish -SO - Can J Cardiol. 2006 Sep;22(11):913-27. doi: 10.1016/s0828-282x(06)70310-5. - -PMID- 23864131 -OWN - NLM -STAT- MEDLINE -DCOM- 20140401 -LR - 20220331 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 34 -IP - 34 -DP - 2013 Sep -TI - More answers to the still unresolved question of nitrate tolerance. -PG - 2666-73 -LID - 10.1093/eurheartj/eht249 [doi] -AB - Organic nitrates are traditionally felt to be a safe adjuvant in the chronic - therapy of patients with coronary artery disease. Despite their long use, - progress in the understanding of the pharmacology and mechanism of action of - these drugs has been achieved only in the last two decades, with the - identification of the role of oxidative stress in the pathophysiology of nitrate - tolerance, with, the discovery of the ancillary effects of nitrates, and with the - demonstration that nitrate therapy has important chronic side effects that might - modify patients' prognosis. These advances are however mostly confined to the - molecular level or to studies in healthy volunteers, and the true impact of - organic nitrates on clinical outcome remains unknown. Complicating this issue, - evidence supports the existence of important differences among the different - drugs belonging to the group, and there are reasons to believe that the nitrates - should not be treated as a homogeneous class. As well, the understanding of the - effects of alternative nitric oxide (NO) donors is currently being developed, and - future studies will need to test whether the properties of these new medications - may compensate and prevent the abnormalities imposed by chronic nitrate therapy. - Intermittent therapy with nitroglycerin and isosorbide mononitrate is now - established in clinical practice, but they should neither be considered a - definitive solution to the problem of nitrate tolerance. Both these strategies - are not deprived of complications, and should currently be seen as a compromise - rather than a way fully to exploit the benefits of NO donor therapy. -FAU - Münzel, Thomas -AU - Münzel T -AD - Department of Cardiology and Angiology, University Medical Center Mainz, Mainz, - Germany. -FAU - Daiber, Andreas -AU - Daiber A -FAU - Gori, Tommaso -AU - Gori T -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130717 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (Nitrates) -RN - 0 (Nitrites) -RN - 0 (Vasodilator Agents) -SB - IM -MH - Angina Pectoris/*drug therapy -MH - Chronic Disease -MH - Drug Tolerance -MH - Humans -MH - Nitrates/*pharmacology -MH - Nitrites/therapeutic use -MH - Vasodilation/drug effects -MH - Vasodilator Agents/*pharmacology -OTO - NOTNLM -OT - Endothelial dysfunction -OT - Nitrate tolerance -OT - Nitrite -OT - Oxidative stress -OT - Peroxynitrite -OT - Vasodilation -EDAT- 2013/07/19 06:00 -MHDA- 2014/04/02 06:00 -CRDT- 2013/07/19 06:00 -PHST- 2013/07/19 06:00 [entrez] -PHST- 2013/07/19 06:00 [pubmed] -PHST- 2014/04/02 06:00 [medline] -AID - eht249 [pii] -AID - 10.1093/eurheartj/eht249 [doi] -PST - ppublish -SO - Eur Heart J. 2013 Sep;34(34):2666-73. doi: 10.1093/eurheartj/eht249. Epub 2013 - Jul 17. - -PMID- 22468983 -OWN - NLM -STAT- MEDLINE -DCOM- 20121025 -LR - 20250626 -IS - 1556-3669 (Electronic) -IS - 1530-5627 (Linking) -VI - 18 -IP - 5 -DP - 2012 Jun -TI - Telemedicine for the reduction of myocardial infarction mortality: a systematic - review and a meta-analysis of published studies. -PG - 323-8 -LID - 10.1089/tmj.2011.0158 [doi] -AB - INTRODUCTION: Advances in electronics and communications have changed modern - medicine: telemedicine allows patient assessment and monitoring to facilitate - healthcare at a distance. The aim of this study was to perform a systematic - review and meta-analysis to assess how telemedicine systems, including early - telemetry of electrocardiograms, can improve health outcomes in patients with - coronary artery disease and, in particular, acute myocardial infarction (AMI). - METHODS: Studies dealing with telemedicine applications in managing AMI that were - conducted before January 22, 2010, published in English or Italian, were - identified in PubMed and ISI Web of Knowledge searches. The meta-analysis was - performed to assess the efficacy of telemedicine versus standard measures in - reducing mortality. Relative risk (RR) with 95% confidence interval was used to - report results and the I(2) test to evaluate heterogeneity. RESULTS: Five of the - 39 articles retrieved were selected; all studies demonstrated the efficacy of - telemedicine applications. Only three studies were judged to be comparable and - suitable for combining data. This meta-analysis showed that the RR for - in-hospital mortality from AMI was 0.65 (95% confidence interval, 0.42-0.99) for - the telemedicine group, without heterogeneity. CONCLUSIONS: Telemedicine may - improve health outcomes of patients with AMI. However, heterogeneity in study - design and end points of most studies limited the number of articles that could - be subjected to our meta-analysis. -FAU - de Waure, Chiara -AU - de Waure C -AD - Institute of Hygiene, Catholic University of the Sacred Heart, Rome, Italy. - chiara.dewaure@rm.unicatt.it -FAU - Cadeddu, Chiara -AU - Cadeddu C -FAU - Gualano, Maria Rosaria -AU - Gualano MR -FAU - Ricciardi, Walter -AU - Ricciardi W -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -DEP - 20120402 -PL - United States -TA - Telemed J E Health -JT - Telemedicine journal and e-health : the official journal of the American - Telemedicine Association -JID - 100959949 -SB - IM -CIN - Telemed J E Health. 2013 Aug;19(8):646. doi: 10.1089/tmj.2012.0238. PMID: - 23841491 -CIN - Telemed J E Health. 2013 Aug;19(8):647. PMID: 24040668 -MH - Acute Disease -MH - Aged -MH - Electrocardiography -MH - Female -MH - Hospital Mortality -MH - Humans -MH - Male -MH - Middle Aged -MH - Myocardial Infarction/diagnosis/*mortality -MH - Risk Assessment -MH - Telemedicine/*methods -MH - Treatment Outcome -EDAT- 2012/04/04 06:00 -MHDA- 2012/10/26 06:00 -CRDT- 2012/04/04 06:00 -PHST- 2012/04/04 06:00 [entrez] -PHST- 2012/04/04 06:00 [pubmed] -PHST- 2012/10/26 06:00 [medline] -AID - 10.1089/tmj.2011.0158 [doi] -PST - ppublish -SO - Telemed J E Health. 2012 Jun;18(5):323-8. doi: 10.1089/tmj.2011.0158. Epub 2012 - Apr 2. - -PMID- 19379059 -OWN - NLM -STAT- MEDLINE -DCOM- 20090715 -LR - 20131121 -IS - 1744-8344 (Electronic) -IS - 1477-9072 (Linking) -VI - 7 -IP - 4 -DP - 2009 Apr -TI - Angiotensin-converting enzyme inhibition by perindopril in the treatment of - cardiovascular disease. -PG - 345-60 -LID - 10.1586/erc.09.2 [doi] -AB - The angiotensin-converting enzyme (ACE) inhibitor perindopril (Coversyl) is a - long-acting lipophilic drug with a high-tissue affinity for the ACE. ACE - inhibition by perindopril has two main effects: it inhibits the angiotensin II - formation and potentiates bradykinin. Perindopril is one of the ACE inhibitors - that has been extensively studied in randomized clinical trials within various - patient populations. The clinical efficacy has been demonstrated in patients with - hypertension, diabetes mellitus, cerebrovascular disease, stable coronary artery - disease (CAD) and heart failure. Perindopril has a positive safety and - tolerability profile. Therefore, perindopril, as an ACE inhibitor, has an - established place in the major clinical treatment guidelines. This article - discusses several studies that have shown that an antihypertensive treatment with - perindopril reduces and prevents cardiovascular events in a large range of - patients with established vascular disease. The observed cardioprotective - benefits of perindopril were independent of blood pressure. The outcome of these - and other trials support the concept of specific cardioprotective properties of - ACE inhibition by perindopril in addition to the blood pressure-lowering effects, - such as anti-atherosclerotic, anti-inflammatory and antithrombotic properties. In - addition, the observed consistency of the treatment benefit across subgroups - indicates that the absolute benefits conferred by treatment are mainly - established by each patient's future risk of vascular complications, rather than - their initial blood pressure level or other risk factors. This article describes - these issues according to the main studies with perindopril or perindopril-based - regimens, concluding that the blood pressure-dependent and -independent - cardioprotective effects extend to all patients with vascular disease. This - concept supports the provision of ACE inhibitor-based treatment, not on the basis - of arbitrary cut-off points for blood pressure but rather on assessment of - vascular risk, which is raised in patients with stable CAD, diabetes and stroke. -FAU - Brugts, Jasper J -AU - Brugts JJ -AD - Department of Cardiology, Erasmus Medical Centers, Gravendijkwal 230, 3015CE - Rotterdam, The Netherlands. j.brugts@erasmusmc.nl -FAU - Ferrari, Roberto -AU - Ferrari R -FAU - Simoons, Maarten L -AU - Simoons ML -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Expert Rev Cardiovasc Ther -JT - Expert review of cardiovascular therapy -JID - 101182328 -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Antihypertensive Agents) -RN - Y5GMK36KGY (Perindopril) -SB - IM -EIN - Expert Rev Cardiovasc Ther. 2009 Jun;7(6):722 -MH - Angiotensin-Converting Enzyme Inhibitors/*administration & dosage/adverse - effects/pharmacokinetics -MH - Antihypertensive Agents/*administration & dosage/adverse effects/pharmacokinetics -MH - Blood Pressure/drug effects -MH - Cardiovascular Diseases/physiopathology/*prevention & control -MH - Humans -MH - Hypertension/complications/drug therapy/physiopathology -MH - Perindopril/*administration & dosage/adverse effects/pharmacokinetics -MH - Randomized Controlled Trials as Topic -RF - 64 -EDAT- 2009/04/22 09:00 -MHDA- 2009/07/16 09:00 -CRDT- 2009/04/22 09:00 -PHST- 2009/04/22 09:00 [entrez] -PHST- 2009/04/22 09:00 [pubmed] -PHST- 2009/07/16 09:00 [medline] -AID - 10.1586/erc.09.2 [doi] -PST - ppublish -SO - Expert Rev Cardiovasc Ther. 2009 Apr;7(4):345-60. doi: 10.1586/erc.09.2. - -PMID- 17989544 -OWN - NLM -STAT- MEDLINE -DCOM- 20080410 -LR - 20071108 -IS - 0952-7907 (Print) -IS - 0952-7907 (Linking) -VI - 20 -IP - 6 -DP - 2007 Dec -TI - Should my outpatient center have a beta-blocker protocol? -PG - 526-30 -AB - PURPOSE OF REVIEW: Perioperative beta-blockade has been advocated by multiple - authors and recent guidelines as a strategy to reduce cardiac risk in noncardiac - surgery. Knowledge about application of this treatment modality to the ambulatory - surgery population is poor. RECENT FINDINGS: Although the initial trial in - patients with a positive stress test undergoing major vascular surgery - demonstrated significantly fewer perioperative cardiac events among those - randomized to perioperative beta-blocker therapy, more recent studies in patients - without documented coronary artery disease undergoing major noncardiac surgical - procedures were unable to demonstrate efficacy. Guidelines from the American - Heart Association/American College of Cardiology have been reported and advocated - class I recommendations for perioperative beta-blockade only for patients - previously taking beta-blockers and those patients with a positive stress test - undergoing vascular surgery. There was insufficient evidence to make a - recommendation in low-risk surgery. SUMMARY: Based upon the available evidence - and guidelines, patients currently taking beta-blockers and undergoing ambulatory - surgery should continue these agents and protocols employing this strategy should - be beneficial. In patients who are not currently taking beta-blockers and in whom - long-term therapy is not warranted, current evidence does not support instituting - prophylactic therapy in the ambulatory surgery population. -FAU - Fleisher, Lee A -AU - Fleisher LA -AD - University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. - fleishel@uphs.upenn.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Opin Anaesthesiol -JT - Current opinion in anaesthesiology -JID - 8813436 -RN - 0 (Adrenergic beta-Antagonists) -SB - IM -MH - Adrenergic beta-Antagonists/*therapeutic use -MH - *Ambulatory Care Facilities -MH - Ambulatory Surgical Procedures/*standards -MH - Clinical Protocols/*standards -MH - Evidence-Based Medicine -MH - Humans -MH - Myocardial Ischemia/prevention & control -MH - Perioperative Care -MH - Practice Guidelines as Topic -MH - Vascular Surgical Procedures/*standards -RF - 27 -EDAT- 2007/11/09 09:00 -MHDA- 2008/04/11 09:00 -CRDT- 2007/11/09 09:00 -PHST- 2007/11/09 09:00 [pubmed] -PHST- 2008/04/11 09:00 [medline] -PHST- 2007/11/09 09:00 [entrez] -AID - 00001503-200712000-00007 [pii] -AID - 10.1097/ACO.0b013e3282f19339 [doi] -PST - ppublish -SO - Curr Opin Anaesthesiol. 2007 Dec;20(6):526-30. doi: 10.1097/ACO.0b013e3282f19339. - -PMID- 23257367 -OWN - NLM -STAT- MEDLINE -DCOM- 20130715 -LR - 20140905 -IS - 1876-7605 (Electronic) -IS - 1936-8798 (Linking) -VI - 5 -IP - 12 -DP - 2012 Dec -TI - Drug-drug interactions in cardiovascular catheterizations and interventions. -PG - 1195-208 -LID - S1936-8798(12)00993-4 [pii] -LID - 10.1016/j.jcin.2012.10.005 [doi] -AB - Patients presenting for invasive cardiovascular procedures are frequently taking - a variety of medications aimed to treat risk factors related to heart and - vascular disease. During the procedure, antithrombotic, sedative, and analgesic - medications are commonly needed, and after interventional procedures, new - medications are often added for primary and secondary prevention of ischemic - events. In addition to these prescribed medications, the use of over-the-counter - drugs and supplements continues to rise. Most elderly patients, for example, are - taking 5 or more prescribed medications and 1 or more supplements, and they often - have some degree of renal insufficiency. This polypharmacy might result in - drug-drug interactions that affect the balance of thrombotic and bleeding events - during the procedure and during long-term treatment. Mixing of anticoagulants, - for instance, might lead to periprocedural bleeding, and this is associated with - an increase in long-term adverse events. Furthermore, the range of possible - interactions with thienopyridine antiplatelets is of concern, because these drugs - are essential to immediate and extended interventional success. The practical - challenges in the field are great-some drug-drug interactions are likely present - yet not well understood due to limited assays, whereas other interactions have - well-described biological effects but seem to be more theoretical, because there - is little to no clinical impact. Interventional providers need to be attentive to - the potential for drug-drug interaction, the associated harm, and the appropriate - action, if any, to minimize the potential for medication-related adverse events. - This review will focus on drug-drug interactions that have the potential to - affect procedural success, either through increases in immediate complications or - compromising longer-term outcome. -CI - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier - Inc. All rights reserved. -FAU - Dunn, Steven P -AU - Dunn SP -AD - Department of Pharmacy Services, University of Virginia, Charlottesville, - Virginia, USA. -FAU - Holmes, David R Jr -AU - Holmes DR Jr -FAU - Moliterno, David J -AU - Moliterno DJ -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - JACC Cardiovasc Interv -JT - JACC. Cardiovascular interventions -JID - 101467004 -RN - 0 (Anticoagulants) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Anticoagulants/administration & dosage/*pharmacology -MH - Cardiac Catheterization -MH - *Catheterization -MH - Drug Interactions -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology -MH - *Percutaneous Coronary Intervention -MH - Platelet Aggregation Inhibitors/*pharmacology -EDAT- 2012/12/22 06:00 -MHDA- 2013/07/17 06:00 -CRDT- 2012/12/22 06:00 -PHST- 2012/08/17 00:00 [received] -PHST- 2012/10/09 00:00 [revised] -PHST- 2012/10/16 00:00 [accepted] -PHST- 2012/12/22 06:00 [entrez] -PHST- 2012/12/22 06:00 [pubmed] -PHST- 2013/07/17 06:00 [medline] -AID - S1936-8798(12)00993-4 [pii] -AID - 10.1016/j.jcin.2012.10.005 [doi] -PST - ppublish -SO - JACC Cardiovasc Interv. 2012 Dec;5(12):1195-208. doi: 10.1016/j.jcin.2012.10.005. - -PMID- 19188413 -OWN - NLM -STAT- MEDLINE -DCOM- 20090602 -LR - 20190709 -IS - 0002-8177 (Print) -IS - 0002-8177 (Linking) -VI - 140 -IP - 2 -DP - 2009 Feb -TI - Atrial fibrillation: pathogenesis, medical-surgical management and dental - implications. -PG - 167-77; quiz 248 -AB - BACKGROUND: Atrial fibrillation (AF) is a cardiac rhythm disturbance arising from - disorganized electrical activity in the atria, and it is accompanied by an - irregular and often rapid ventricular response. It is the most common clinically - significant dysrhythmia in the general and older population. TYPES OF STUDIES - REVIEWED: The authors conducted a MEDLINE search using the key terms "atrial - fibrillation," "epidemiology," "pathophysiology," "treatment" and "dentistry." - They selected contemporaneous articles published in peer-reviewed journals and - gave preference to articles reporting randomized controlled trials. CLINICAL - IMPLICATIONS: The anticoagulant warfarin frequently is prescribed to prevent - stroke caused by cardiogenic thromboemboli arising from stagnant blood in poorly - contracting atria. Most dental procedures and a limited number of surgical - procedures can be performed without altering warfarin dosage if the international - normalized ratio value is within the therapeutic range of 2.0 to 3.0. Certain - analgesic agents, antibiotic agents, antifungal agents and sedative hypnotics, - however, should not be prescribed without consultation with the patient's - physician because these medications may alter the patient's risk of hemorrhage - and stroke. CONCLUSIONS: AF affects nearly 2.5 million Americans, most of who are - older than 60 years. Consultation with the patient's physician to discuss the - planned dental treatment often is appropriate, especially for people who - frequently have comorbid diseases such as coronary artery disease, congestive - heart failure, diabetes and thyrotoxicosis, which are treated with multiple drug - regimens. -FAU - Friedlander, Arthur H -AU - Friedlander AH -AD - VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA. - arthur.friedlander@med.va.gov -FAU - Yoshikawa, Thomas T -AU - Yoshikawa TT -FAU - Chang, Donald S -AU - Chang DS -FAU - Feliciano, Zenaida -AU - Feliciano Z -FAU - Scully, Crispian -AU - Scully C -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - J Am Dent Assoc -JT - Journal of the American Dental Association (1939) -JID - 7503060 -RN - 0 (Anticoagulants) -RN - 5Q7ZVV76EI (Warfarin) -SB - IM -CIN - J Am Dent Assoc. 2009 May;140(5):515; author reply 515-6. doi: - 10.14219/jada.archive.2009.0202. PMID: 19411510 -CIN - J Am Dent Assoc. 2009 May;140(5):515. doi: 10.14219/jada.archive.2009.0204. PMID: - 19411511 -MH - Anticoagulants/*therapeutic use -MH - Atrial Fibrillation/physiopathology/*therapy -MH - Contraindications -MH - *Dental Care for Chronically Ill -MH - Hemorrhage/prevention & control -MH - Humans -MH - Oral Surgical Procedures -MH - Stroke/prevention & control -MH - Warfarin/*therapeutic use -RF - 90 -EDAT- 2009/02/04 09:00 -MHDA- 2009/06/03 09:00 -CRDT- 2009/02/04 09:00 -PHST- 2009/02/04 09:00 [entrez] -PHST- 2009/02/04 09:00 [pubmed] -PHST- 2009/06/03 09:00 [medline] -AID - 140/2/167 [pii] -AID - 10.14219/jada.archive.2009.0130 [doi] -PST - ppublish -SO - J Am Dent Assoc. 2009 Feb;140(2):167-77; quiz 248. doi: - 10.14219/jada.archive.2009.0130. - -PMID- 18159955 -OWN - NLM -STAT- MEDLINE -DCOM- 20080215 -LR - 20250623 -IS - 0033-7587 (Print) -IS - 0033-7587 (Linking) -VI - 169 -IP - 1 -DP - 2008 Jan -TI - A systematic review of epidemiological associations between low and moderate - doses of ionizing radiation and late cardiovascular effects, and their possible - mechanisms. -PG - 99-109 -AB - Little, M. P., Tawn, E. J., Tzoulaki, I., Wakeford, R., Hildebrandt, G., Paris, - F., Tapio, S. and Elliott, P. A Systematic Review of Epidemiological Associations - Between Low and Moderate Doses of Ionizing Radiation and Late Cardiovascular - Effects, and Their Possible Mechanisms. Radiat. Res. 169, 99-109 (2008). The link - between high doses of ionizing radiation and damage to the heart and coronary - arteries is established. In this paper, we systematically review the - epidemiological evidence for associations between low and moderate doses (<5 Gy) - of ionizing radiation and late-occurring cardiovascular disease. Risks per unit - dose in epidemiological studies vary over at least two orders of magnitude, - possibly a result of confounding factors. An examination of possible biological - mechanisms indicates that the most likely causative effect of radiation exposure - is damage to endothelial cells and subsequent induction of an inflammatory - response, although it seems unlikely that this would extend to low-dose and - low-dose-rate exposure. However, a role for somatic mutation has been proposed - that would indicate a stochastic effect. In the absence of a convincing - mechanistic explanation of epidemiological evidence that is less than persuasive - at present, a cause-and-effect interpretation of the reported statistical - associations cannot be reliably inferred, although neither can it be reliably - excluded. Further epidemiological and biological evidence will allow a firmer - conclusion to be drawn. -FAU - Little, M P -AU - Little MP -AD - Department of Epidemiology and Public Health, Imperial College Faculty of - Medicine, London W2 1PG, United Kingdom. mark.little@imperial.ac.uk -FAU - Tawn, E J -AU - Tawn EJ -FAU - Tzoulaki, I -AU - Tzoulaki I -FAU - Wakeford, R -AU - Wakeford R -FAU - Hildebrandt, G -AU - Hildebrandt G -FAU - Paris, F -AU - Paris F -FAU - Tapio, S -AU - Tapio S -FAU - Elliott, P -AU - Elliott P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Systematic Review -PL - United States -TA - Radiat Res -JT - Radiation research -JID - 0401245 -SB - IM -MH - Animals -MH - Cardiovascular Diseases/*epidemiology -MH - Cardiovascular System/*radiation effects -MH - Dose-Response Relationship, Radiation -MH - Environmental Exposure -MH - Humans -MH - Nuclear Weapons -MH - Radiation, Ionizing -RF - 85 -EDAT- 2007/12/28 09:00 -MHDA- 2008/02/19 09:00 -CRDT- 2007/12/28 09:00 -PHST- 2007/04/20 00:00 [received] -PHST- 2007/08/29 00:00 [accepted] -PHST- 2007/12/28 09:00 [pubmed] -PHST- 2008/02/19 09:00 [medline] -PHST- 2007/12/28 09:00 [entrez] -AID - RR1070 [pii] -AID - 10.1667/RR1070.1 [doi] -PST - ppublish -SO - Radiat Res. 2008 Jan;169(1):99-109. doi: 10.1667/RR1070.1. - -PMID- 22364309 -OWN - NLM -STAT- MEDLINE -DCOM- 20130530 -LR - 20220210 -IS - 1525-1403 (Electronic) -IS - 1094-7159 (Linking) -VI - 15 -IP - 6 -DP - 2012 Nov-Dec -TI - Effect of spinal cord stimulation in patients with refractory angina: evidence - from observational studies. -PG - 542-9; disdcussion 549 -LID - 10.1111/j.1525-1403.2012.00430.x [doi] -AB - OBJECTIVES:   To review the evidence in observational studies of the effect of - spinal cord stimulation (SCS) in patients with refractory angina pectoris (RAP) - due to obstructive coronary artery disease. The effect of SCS in patients with - refractory microvascular angina (MVA) also was assessed. MATERIALS AND METHODS:   - We reviewed the observational studies, published from 1987 to 2010, which - investigated the effects of SCS on RAP. The number of angina attacks and that of - taken nitrate tablets, as well as the class of angina, were considered as main - outcome variables. The occurrence of adverse events related to the treatment also - was assessed. RESULTS:   The results showed a consistent reduction of the number - of angina attacks (by 45-84%) and of consumption of short-acting nitrate tablets - (by -75% to -94%), whereas the New York Heart Association and Canadian - Cardiovascular Society class of angina were significantly improved in some - studies. No case fatalities related to the therapy were reported. Significant - clinical benefits were observed in some studies in patients with refractory MVA. - Device-related infections and catheter dislodgment were the most significant and - frequent side-effects, respectively. CONCLUSIONS:   In observational studies, SCS - showed to be an effective form of treatment for RAP, including refractory MVA. - The treatment appears to be safe both at short- and long-term follow-up. -CI - © 2012 International Neuromodulation Society. -FAU - Lanza, Gaetano Antonio -AU - Lanza GA -AD - Department of Cardiovascular Medicine, Università Cattolica del Sacro Cuore, - Rome, Italy. g.a.lanza@rm.unicatt.it -FAU - Barone, Lucy -AU - Barone L -FAU - Di Monaco, Antonio -AU - Di Monaco A -LA - eng -PT - Journal Article -PT - Review -DEP - 20120224 -PL - United States -TA - Neuromodulation -JT - Neuromodulation : journal of the International Neuromodulation Society -JID - 9804159 -SB - IM -MH - Angina Pectoris/etiology/*therapy -MH - Arterial Occlusive Diseases/complications -MH - Databases, Factual/statistics & numerical data -MH - Female -MH - Humans -MH - Male -MH - Observation -MH - Retrospective Studies -MH - Spinal Cord/*physiology -MH - Spinal Cord Stimulation/*methods -EDAT- 2012/03/01 06:00 -MHDA- 2013/06/01 06:00 -CRDT- 2012/02/28 06:00 -PHST- 2012/02/28 06:00 [entrez] -PHST- 2012/03/01 06:00 [pubmed] -PHST- 2013/06/01 06:00 [medline] -AID - S1094-7159(12)60059-2 [pii] -AID - 10.1111/j.1525-1403.2012.00430.x [doi] -PST - ppublish -SO - Neuromodulation. 2012 Nov-Dec;15(6):542-9; disdcussion 549. doi: - 10.1111/j.1525-1403.2012.00430.x. Epub 2012 Feb 24. - -PMID- 19235364 -OWN - NLM -STAT- MEDLINE -DCOM- 20090423 -LR - 20250623 -IS - 0048-7554 (Print) -IS - 0048-7554 (Linking) -VI - 23 -IP - 4 -DP - 2008 Oct-Dec -TI - A systematic review of the relation between long-term exposure to ambient air - pollution and chronic diseases. -PG - 243-97 -AB - We conducted a systematic review of all studies published between 1950 and 2007 - of associations between long-term exposure to ambient air pollution and the risks - in adults of nonaccidental mortality and the incidence and mortality from cancer - and cardiovascular and respiratory diseases. We searched bibliographic databases - for cohort and case-control studies, abstracted characteristics of their design - and conduct, and synthesized the quantitative findings in tabular and graphic - form. We assessed heterogeneity, estimated pooled effects for specific - pollutants, and conducted sensitivity analyses according to selected - characteristics of the studies. Our analysis showed that long-term exposure to - PM2.5 increases the risk of nonaccidental mortality by 6% per a 10 microg/m3 - increase, independent of age, gender, and geographic region. Exposure to PM2.5 - was also associated with an increased risk of mortality from lung cancer (range: - 15% to 21% per a 10 microg/m3 increase) and total cardiovascular mortality - (range: 12% to 14% per a 10 microg/m3 increase). In addition, living close to - busy traffic appears to be associated with elevated risks of these three - outcomes. Suggestive evidence was found that exposure to PM2.5 is positively - associated with mortality from coronary heart diseases and exposure to SO2 - increases mortality from lung cancer. For the other pollutants and health - outcomes, the data were insufficient data to make solid conclusions. -FAU - Chen, Hong -AU - Chen H -AD - Department of Epidemiology and Biostatistics, McGill University, Montreal, - Quebec. -FAU - Goldberg, Mark S -AU - Goldberg MS -FAU - Villeneuve, Paul J -AU - Villeneuve PJ -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Systematic Review -PL - Germany -TA - Rev Environ Health -JT - Reviews on environmental health -JID - 0425754 -RN - 0 (Air Pollutants) -RN - 0 (Particulate Matter) -SB - IM -MH - Air Pollutants/adverse effects -MH - Air Pollution/*adverse effects -MH - Cardiovascular Diseases/mortality -MH - Chronic Disease -MH - Environmental Exposure/*adverse effects -MH - Humans -MH - Lung Neoplasms/mortality -MH - Particulate Matter/adverse effects -RF - 131 -EDAT- 2009/02/25 09:00 -MHDA- 2009/04/25 09:00 -CRDT- 2009/02/25 09:00 -PHST- 2009/02/25 09:00 [entrez] -PHST- 2009/02/25 09:00 [pubmed] -PHST- 2009/04/25 09:00 [medline] -AID - 10.1515/reveh.2008.23.4.243 [doi] -PST - ppublish -SO - Rev Environ Health. 2008 Oct-Dec;23(4):243-97. doi: 10.1515/reveh.2008.23.4.243. - -PMID- 19307690 -OWN - NLM -STAT- MEDLINE -DCOM- 20090630 -LR - 20220409 -IS - 1734-1140 (Print) -IS - 1734-1140 (Linking) -VI - 61 -IP - 1 -DP - 2009 Jan-Feb -TI - ICAM-1 signaling in endothelial cells. -PG - 22-32 -AB - Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the - immunoglobulin (Ig) superfamily and is critical for the firm arrest and - transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is - constitutively present on endothelial cells, but its expression is increased by - proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in - atherosclerotic and transplant-associated atherosclerotic tissue and in animal - models of atherosclerosis. Additionally, ICAM-1 has been implicated in the - progression of autoimmune diseases. We and others have shown that the ligation of - ICAM-1 on the surface of endothelial or smooth muscle cells with monoclonal - antibodies, via its main leukocyte ligand, lymphocyte function associated - molecule (LFA)-1, or with antibodies derived from patient serum, leads to the - activation of several proinflammatory signaling cascades, and to the - rearrangement of the actin cytoskeleton. A circulating or soluble form of ICAM-1 - (sICAM-1) has been measured in various body fluids, with elevated levels being - observed in patients with atherosclerosis, heart failure, coronary artery disease - and transplant vasculopathy. sICAM-1 has signaling properties in several cell - types, including EC, and invokes a range of proinflammatory responses. Thus, we - propose that in addition to acting as a leukocyte adhesion molecule, ICAM-1 - directly contributes to inflammatory responses within the blood vessel wall by - increasing endothelial cell activation and augmenting atherosclerotic plaque - formation. -FAU - Lawson, Charlotte -AU - Lawson C -AD - Veterinary Basic Sciences, Royal Veterinary College, London, UK. - chlawson@rvc.ac.uk -FAU - Wolf, Sabine -AU - Wolf S -LA - eng -PT - Journal Article -PT - Review -PL - Switzerland -TA - Pharmacol Rep -JT - Pharmacological reports : PR -JID - 101234999 -RN - 126547-89-5 (Intercellular Adhesion Molecule-1) -SB - IM -MH - Animals -MH - Atherosclerosis/*physiopathology -MH - Autoimmune Diseases/physiopathology -MH - Endothelial Cells/*metabolism -MH - Gene Expression Regulation -MH - Humans -MH - Intercellular Adhesion Molecule-1/*metabolism -MH - Muscle, Smooth, Vascular/cytology -MH - Myocytes, Smooth Muscle/metabolism -MH - Signal Transduction -RF - 102 -EDAT- 2009/03/25 09:00 -MHDA- 2009/07/01 09:00 -CRDT- 2009/03/25 09:00 -PHST- 2008/09/25 00:00 [received] -PHST- 2009/01/08 00:00 [revised] -PHST- 2009/03/25 09:00 [entrez] -PHST- 2009/03/25 09:00 [pubmed] -PHST- 2009/07/01 09:00 [medline] -AID - S1734-1140(09)70004-0 [pii] -AID - 10.1016/s1734-1140(09)70004-0 [doi] -PST - ppublish -SO - Pharmacol Rep. 2009 Jan-Feb;61(1):22-32. doi: 10.1016/s1734-1140(09)70004-0. - -PMID- 16529551 -OWN - NLM -STAT- MEDLINE -DCOM- 20060510 -LR - 20191109 -IS - 1871-5257 (Print) -IS - 1871-5257 (Linking) -VI - 4 -IP - 1 -DP - 2006 Jan -TI - Angiotensin receptor blockers in hypertension and cardiovascular diseases. -PG - 67-73 -AB - Angiotensin receptor blockers are the newest class of antihypertensive agents - marketed for the treatment of hypertension. There is now an important amount of - evidence indicating that this class of drugs exerts beneficial effects in - patients with a variety of cardiovascular disorders. Evidence-based medicine - includes well controlled studies with mortality and morbidity endpoints in - patients with left ventricular dysfunction after a myocardial infarction, - congestive heart failure, cerebrovascular disease, type-2 diabetic subjects with - renal dysfunction and high-risk hypertensive patients. In addition to these hard - endpoints, treatment with angiotensin receptor blockers prevents the development - of type-2 diabetes, promotes a more pronounced regression of left ventricular - hypertrophy, decreases microalbuminuria and proteinuria in renal patients, - ameliorates coronary and peripheral vascular endothelial dysfunction and - decreases plasma levels of several markers of vascular inflammation. In summary, - angiotensin receptor blockers are antihypertensive drugs with a very good profile - in terms of efficacy, tolerability and cardiovascular protection. They represent - an important step in the search for the ideal antihypertensive agent. -FAU - de la Sierra, Alejandro -AU - de la Sierra A -AD - Hypertension Unit, Department of Internal Medicine, Hospital Clinic, - 170-Villarroel, 08036-Barcelona, Spain. asierra@clinic.ub.es -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Cardiovasc Hematol Agents Med Chem -JT - Cardiovascular & hematological agents in medicinal chemistry -JID - 101266881 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/classification/*therapeutic use -MH - Antihypertensive Agents/classification/*therapeutic use -MH - Cardiovascular Diseases/*drug therapy -MH - Humans -MH - Hypertension/*drug therapy -MH - Kidney Diseases/drug therapy -MH - Renin-Angiotensin System/drug effects -RF - 42 -EDAT- 2006/03/15 09:00 -MHDA- 2006/05/11 09:00 -CRDT- 2006/03/15 09:00 -PHST- 2006/03/15 09:00 [pubmed] -PHST- 2006/05/11 09:00 [medline] -PHST- 2006/03/15 09:00 [entrez] -AID - 10.2174/187152506775268839 [doi] -PST - ppublish -SO - Cardiovasc Hematol Agents Med Chem. 2006 Jan;4(1):67-73. doi: - 10.2174/187152506775268839. - -PMID- 21148652 -OWN - NLM -STAT- MEDLINE -DCOM- 20110126 -LR - 20180126 -IS - 1471-6771 (Electronic) -IS - 0007-0912 (Linking) -VI - 105 Suppl 1 -DP - 2010 Dec -TI - Anaesthetic considerations with the metabolic syndrome. -PG - i24-33 -LID - 10.1093/bja/aeq293 [doi] -AB - The rising incidence of obesity has led to increased prevalence of a distinct, - obesity-related metabolic syndrome. This syndrome is characterized by truncal - obesity, insulin resistance, altered lipid levels, and hypertension. Definition - of the metabolic syndrome rests on a set of clinical criteria instead of a single - diagnostic test. It carries a different risk profile than obesity alone, and - poses special challenges for the anaesthesiologist. These include preoperative - risk stratification for common comorbidities, identifying reasonable thresholds - for implementing preoperative risk reduction, overcoming obesity-related issues - in intraoperative management, and delivering safe postoperative care. The - metabolic syndrome predisposes to coronary artery disease, congestive heart - failure, obstructive sleep apnoea, pulmonary dysfunction, and deep venous - thrombosis. Because its different presentations can have different risk profiles, - anaesthesiologists should assess the cumulative risk of each component of the - metabolic syndrome separately, which significantly complicates preoperative - management. Since obesity itself is difficult to treat, preoperative risk - reduction can be difficult. Few data exist to inform best practice as to the - anaesthetic care of patients with metabolic syndrome. This review evaluates and - synthesizes current evidence regarding perioperative care for patients with the - metabolic syndrome, including indications for preoperative testing; use of - aspirin, β-blockers, statins, heparin, and angiotensin-converting enzyme - inhibitors; anaesthetic strategies including regional anaesthesia; and - postoperative management including continuous positive pressure ventilation by - mask, prevention of pulmonary embolism, and indications for advanced respiratory - monitoring. -FAU - Tung, A -AU - Tung A -AD - Department of Anesthesia and Critical Care, University of Chicago, 5841 S. - Maryland Avenue MC4028, Chicago, IL 60637, USA. atung@dacc.uchicago.edu -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Br J Anaesth -JT - British journal of anaesthesia -JID - 0372541 -SB - IM -MH - Anesthesia/*methods -MH - Cardiovascular Diseases/complications -MH - Humans -MH - Lung Diseases/complications -MH - Metabolic Syndrome/*complications -MH - Perioperative Care/*methods -MH - Risk Assessment/methods -MH - Risk Reduction Behavior -MH - Sleep Apnea, Obstructive/complications -EDAT- 2010/12/22 06:00 -MHDA- 2011/01/28 06:00 -CRDT- 2010/12/15 06:00 -PHST- 2010/12/15 06:00 [entrez] -PHST- 2010/12/22 06:00 [pubmed] -PHST- 2011/01/28 06:00 [medline] -AID - S0007-0912(17)33392-5 [pii] -AID - 10.1093/bja/aeq293 [doi] -PST - ppublish -SO - Br J Anaesth. 2010 Dec;105 Suppl 1:i24-33. doi: 10.1093/bja/aeq293. - -PMID- 19811239 -OWN - NLM -STAT- MEDLINE -DCOM- 20100106 -LR - 20191111 -IS - 1473-0804 (Electronic) -IS - 1369-7137 (Linking) -VI - 12 Suppl 1 -DP - 2009 -TI - Blood pressure through aging and menopause. -PG - 36-40 -AB - Together with the aging process, hypertension is the main risk factor - contributing to the increase in cardiovascular morbidity and mortality in - postmenopausal women, with a prevalence of around 60% in women older than 65 - years. Considering that hypertension is a modifiable risk factor, the - understanding of its epidemiology and pathophysiology and the development of - appropriate therapeutic strategies are conceivably crucial in reducing - cardiovascular risk. The high prevalence of hypertension in older women is - largely due to the progressive stiffening of the arterial structure which - accompanies the aging process in both sexes. However, the abrupt fall in - circulating estrogen levels might independently contribute to the rise in blood - pressure, through partly unknown mechanisms, such as a direct effect on the - arterial wall, the activation of the renin-angiotensin system and of the - sympathetic nervous system. Postmenopausal hypertension fosters the development - of left ventricular hypertrophy and is the main factor contributing to coronary - artery disease, chronic heart failure and stroke in older women. Recent analysis - demonstrates that men and women receive a similar benefit from antihypertensive - therapy in terms of reduction of cardiovascular morbidity and mortality and, - considering that generally the response to different drugs is not different - between the sexes, currently there is no need to use specific antihypertensive - drug classes after menopause. Finally, although observational studies have shown - that hormone replacement therapy is associated with lower cardiovascular risk and - lower blood pressure values, randomized clinical trials have conversely denied - this benefit and demonstrated rather that this therapeutical approach increases - the risk of cardiovascular events. -FAU - Taddei, S -AU - Taddei S -AD - Department of Internal Medicine, University of Pisa, Pisa, Italy. -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Climacteric -JT - Climacteric : the journal of the International Menopause Society -JID - 9810959 -RN - 0 (Estrogens) -SB - IM -MH - Aging/*physiology -MH - Blood Pressure/*physiology -MH - Cardiovascular Diseases/*etiology/mortality/prevention & control -MH - Estrogens/blood -MH - Female -MH - Humans -MH - Hypertension/drug therapy/epidemiology/*physiopathology -MH - Menopause/*physiology -MH - Postmenopause/physiology -MH - Prevalence -MH - Risk Factors -RF - 14 -EDAT- 2009/10/16 06:00 -MHDA- 2010/01/07 06:00 -CRDT- 2009/10/09 06:00 -PHST- 2009/10/09 06:00 [entrez] -PHST- 2009/10/16 06:00 [pubmed] -PHST- 2010/01/07 06:00 [medline] -AID - 10.1080/13697130903004758 [pii] -AID - 10.1080/13697130903004758 [doi] -PST - ppublish -SO - Climacteric. 2009;12 Suppl 1:36-40. doi: 10.1080/13697130903004758. - -PMID- 18574453 -OWN - NLM -STAT- MEDLINE -DCOM- 20081008 -LR - 20250529 -IS - 0007-1188 (Print) -IS - 1476-5381 (Electronic) -IS - 0007-1188 (Linking) -VI - 155 -IP - 2 -DP - 2008 Sep -TI - The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and - troubles. -PG - 170-84 -LID - 10.1038/bjp.2008.263 [doi] -AB - Nitroglycerin (glyceryl trinitrate; GTN) is the most prominent representative of - the organic nitrates or nitrovasodilators, a class of compounds that have been - used clinically since the late nineteenth century for the treatment of coronary - artery disease (angina pectoris), congestive heart failure and myocardial - infarction. Medline lists more than 15 000 publications on GTN and other organic - nitrates, but the mode of action of these drugs is still largely a mystery. In - the first part of this article, we give an overview on the molecular mechanisms - of GTN biotransformation resulting in vascular cyclic GMP accumulation and - vasodilation with focus on the role of mitochondrial aldehyde dehydrogenase - (ALDH2) and the link between the ALDH2 reaction and activation of vascular - soluble guanylate cyclase (sGC). In particular, we address the identity of the - bioactive species that activates sGC and the potential involvement of nitrite as - an intermediate, describe our recent findings suggesting that ALDH2 catalyses - direct 3-electron reduction of GTN to NO and discuss possible reaction - mechanisms. In the second part, we discuss contingent processes leading to - markedly reduced sensitivity of blood vessels to GTN, referred to as vascular - nitrate tolerance. Again, we focus on ALDH2 and describe the current controversy - on the role of ALDH2 inactivation in tolerance development. Finally, we emphasize - some of the most intriguing, in our opinion, unresolved puzzles of GTN - pharmacology that urgently need to be addressed in future studies. -FAU - Mayer, B -AU - Mayer B -AD - Department of Pharmacology and Toxicology, Karl-Franzens-University Graz, Graz, - Austria. mayer@uni-graz.at -FAU - Beretta, M -AU - Beretta M -LA - eng -GR - P 20669/FWF_/Austrian Science Fund FWF/Austria -GR - W 901/FWF_/Austrian Science Fund FWF/Austria -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080623 -PL - England -TA - Br J Pharmacol -JT - British journal of pharmacology -JID - 7502536 -RN - 0 (Nitrates) -RN - G59M7S0WS3 (Nitroglycerin) -SB - IM -MH - Animals -MH - *Biotransformation -MH - Drug Tolerance/*physiology -MH - Humans -MH - Nitrates/*adverse effects/pharmacology -MH - Nitroglycerin/adverse effects/metabolism/*pharmacology/therapeutic use -MH - United States -PMC - PMC2538691 -EDAT- 2008/06/25 09:00 -MHDA- 2008/10/09 09:00 -PMCR- 2009/09/01 -CRDT- 2008/06/25 09:00 -PHST- 2008/06/25 09:00 [pubmed] -PHST- 2008/10/09 09:00 [medline] -PHST- 2008/06/25 09:00 [entrez] -PHST- 2009/09/01 00:00 [pmc-release] -AID - bjp2008263 [pii] -AID - 10.1038/bjp.2008.263 [doi] -PST - ppublish -SO - Br J Pharmacol. 2008 Sep;155(2):170-84. doi: 10.1038/bjp.2008.263. Epub 2008 Jun - 23. - -PMID- 23623945 -OWN - NLM -STAT- MEDLINE -DCOM- 20140205 -LR - 20220316 -IS - 1873-2933 (Electronic) -IS - 0009-9120 (Linking) -VI - 46 -IP - 12 -DP - 2013 Aug -TI - Analytical and assay issues for use of cardiac troponin testing for risk - stratification in primary care. -PG - 969-978 -LID - S0009-9120(13)00153-7 [pii] -LID - 10.1016/j.clinbiochem.2013.04.013 [doi] -AB - Cardiac troponin is the standard marker for diagnosis of acute myocardial - infarction and risk stratification of patients who present to an emergency - department with signs and symptoms of acute cardiac ischemia. Over the past few - years, the analytical sensitivity of assays for cardiac troponin has improved - significantly to the point where a detectable amount of troponin can be measured - in essentially all healthy subjects. Recent studies have shown that use of a - highly sensitive troponin assays may provide value to traditional markers of - primary disease risk for patients, i.e., for those who have no history of heart - disease. There are barriers to the adoption of cardiac troponin for screening - high risk cohorts such as the elderly, diabetics and perhaps even the - asymptomatic population. Strategies used for the assignment of cutoff - concentrations in acute care, i.e., the 99 th percentile, may not be appropriate - for primary care as changes over baseline levels may provide more accurate - information of risk than cross-sectional results. A review of biological - variation has shown that cardiac troponin as a biomarker has low index of - individuality, indicating that reference values are of little utility. Whether or - not cardiac troponin can be released in reversible injury is a debate that could - have significance for detecting minor myocardial injury. A major hurdle for use - of troponin in primary care is the lack of assay standardization and nomenclature - for the different generations of troponin assays. Standardization requires - knowledge of what is released after cardiac injury and what the various cardiac - troponin assays are measuring. Currently it is not clear if the cardiac troponin - release after ischemic injury is identical to that in circulation of healthy - individuals. This may affect the design of future assays and standardization - approaches. There is potential that a marker of myocardial injury such as - troponin can add to the value of existing indicators and biomarkers of - cardiovascular disease risk. Additional analytical and clinical validations are - needed to fully elucidate cardiac troponin metabolism and resolve ongoing - clinical and laboratory issues. While these issues are directed to the use of - troponin in primary care, most of these concepts are relevant to the use of - troponin in acute coronary syndromes as well. -CI - Copyright © 2013 The Canadian Society of Clinical Chemists. Published by Elsevier - Inc. All rights reserved. -FAU - Wu, Alan H B -AU - Wu AHB -AD - Department of Laboratory Medicine, University of California, San Francisco, CA, - USA. Electronic address: wualan@labmed2.ucsf.edu. -FAU - Christenson, Robert H -AU - Christenson RH -AD - Department of Pathology, University of Maryland, Baltimore, MD, USA. Electronic - address: rchristenson@umm.edu. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130425 -PL - United States -TA - Clin Biochem -JT - Clinical biochemistry -JID - 0133660 -RN - 0 (Troponin) -SB - IM -MH - Chemistry Techniques, Analytical/*methods -MH - Humans -MH - Immunoassay/*methods -MH - Myocardium/*metabolism -MH - *Primary Health Care -MH - Risk Assessment -MH - Troponin/*metabolism -OTO - NOTNLM -OT - ACC -OT - AHA -OT - AMI -OT - American College of Cardiology -OT - American Heart Association -OT - Biological variation -OT - CK -OT - CV(A), CV(I), CV(G) -OT - Cardiac troponin -OT - ESC -OT - European Society of Cardiology -OT - IFCC -OT - II -OT - ISO -OT - International Federation of Clinical Chemistry -OT - International Organization for Standardization -OT - International System of Units -OT - NACB -OT - National Academy of Clinical Biochemistry -OT - Primary cardiovascular disease risk -OT - RCV -OT - RM -OT - ROC -OT - Reversible injury -OT - SI -OT - SMCD -OT - SRM -OT - Standardization -OT - Standardization of Markers of Cardiac Damage -OT - WHO -OT - World Health Organization -OT - acute myocardial infarction -OT - cTnI and cTnT -OT - cardiac troponin I and T -OT - coefficient of variance analytical, intraindividual, and interindividual -OT - creatine kinase -OT - index of individuality -OT - receiver operating characteristic -OT - reference change value -OT - reference material -OT - standard reference material -EDAT- 2013/04/30 06:00 -MHDA- 2014/02/06 06:00 -CRDT- 2013/04/30 06:00 -PHST- 2013/03/20 00:00 [received] -PHST- 2013/04/15 00:00 [revised] -PHST- 2013/04/17 00:00 [accepted] -PHST- 2013/04/30 06:00 [entrez] -PHST- 2013/04/30 06:00 [pubmed] -PHST- 2014/02/06 06:00 [medline] -AID - S0009-9120(13)00153-7 [pii] -AID - 10.1016/j.clinbiochem.2013.04.013 [doi] -PST - ppublish -SO - Clin Biochem. 2013 Aug;46(12):969-978. doi: 10.1016/j.clinbiochem.2013.04.013. - Epub 2013 Apr 25. - -PMID- 20353903 -OWN - NLM -STAT- MEDLINE -DCOM- 20111115 -LR - 20220408 -IS - 1952-4021 (Electronic) -IS - 0953-1424 (Linking) -VI - 23 -IP - 2 -DP - 2010 Jun -TI - Magnesium and cardiovascular system. -PG - 60-72 -LID - 10.1684/mrh.2010.0202 [doi] -AB - Hypomagnesemia is common in hospitalized patients, especially in the elderly with - coronary artery disease (CAD) and/or those with chronic heart failure. - Hypomagnesemia is associated with an increased incidence of diabetes mellitus, - metabolic syndrome, mortality rate from CAD and all causes. Magnesium - supplementation improves myocardial metabolism, inhibits calcium accumulation and - myocardial cell death; it improves vascular tone, peripheral vascular resistance, - afterload and cardiac output, reduces cardiac arrhythmias and improves lipid - metabolism. Magnesium also reduces vulnerability to oxygen-derived free radicals, - improves human endothelial function and inhibits platelet function, including - platelet aggregation and adhesion, which potentially gives magnesium physiologic - and natural effects similar to adenosine-diphosphate inhibitors such as - clopidogrel. The data regarding its use in patients with acute myocardial - infarction (AMI) is conflicting. Although some previous, relatively small - randomized clinical trials demonstrated a remarkable reduction in mortality when - administered to relatively high risk AMI patients, two recently published - large-scale randomized clinical trials (the Fourth International Study of Infarct - Survival and Magnesium in Coronaries) failed to show any advantage of intravenous - magnesium over placebo. Nevertheless, there are theoretical potential benefits of - magnesium supplementation as a cardioprotective agent in CAD patients, as well as - promising results from previous work in animal and humans. These studies are cost - effective, easy to handle and are relatively free of adverse effects, which gives - magnesium a role in treating CAD patients, especially high-risk groups such as - CAD patients with heart failure, the elderly and hospitalized patients with - hypomagnesemia. Furthermore, magnesium therapy is indicated in life-threatening - ventricular arrhythmias such as Torsades de Pointes and intractable ventricular - tachycardia. -FAU - Shechter, Michael -AU - Shechter M -AD - Leviev Heart Center, Chaim Sheba Medical Center, Tel Hashomern and the Sackler - Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel. - shechtes@netvision.net.il -LA - eng -PT - Journal Article -PT - Review -DEP - 20100331 -PL - England -TA - Magnes Res -JT - Magnesium research -JID - 8900948 -RN - 0 (Anticoagulants) -RN - I38ZP9992A (Magnesium) -SB - IM -MH - Anticoagulants/pharmacology -MH - Blood Vessels/drug effects/metabolism -MH - Cardiovascular System/drug effects/*metabolism/physiopathology -MH - Endothelium, Vascular/drug effects/physiopathology -MH - Humans -MH - Lipid Metabolism/drug effects -MH - Magnesium/administration & dosage/blood/*metabolism -EDAT- 2010/04/01 06:00 -MHDA- 2011/11/16 06:00 -CRDT- 2010/04/01 06:00 -PHST- 2010/04/01 06:00 [entrez] -PHST- 2010/04/01 06:00 [pubmed] -PHST- 2011/11/16 06:00 [medline] -AID - mrh.2010.0202 [pii] -AID - 10.1684/mrh.2010.0202 [doi] -PST - ppublish -SO - Magnes Res. 2010 Jun;23(2):60-72. doi: 10.1684/mrh.2010.0202. Epub 2010 Mar 31. - -PMID- 18454336 -OWN - NLM -STAT- MEDLINE -DCOM- 20090112 -LR - 20211020 -IS - 1861-0692 (Electronic) -IS - 1861-0684 (Linking) -VI - 97 -IP - 7 -DP - 2008 Jul -TI - RAS blockade with ARB and ACE inhibitors: current perspective on rationale and - patient selection. -PG - 418-31 -LID - 10.1007/s00392-008-0668-3 [doi] -AB - Cardiovascular disease represents a continuum that starts with risk factors such - as hypertension and progresses to atherosclerosis, target organ damage, and - ultimately to myocardial infarction, heart failure, stroke or death. - Renin-angiotensin system (RAS) blockade with angiotensin converting enzyme (ACE) - inhibitors or angiotensin AT(1)-receptor blockers (ARBs) has turned out to be - beneficial at all stages of this continuum. Both classes of agent can prevent or - reverse endothelial dysfunction and atherosclerosis, thereby reducing the risk of - cardiovascular events. Such a reduction has been shown mainly for ACE inhibitors - in patients with coronary artery disease, but recent studies revealed that ARBs - are not inferior in this respect. However, no such data are currently available - on the combination of these drugs. Both ACE inhibitors and ARBs have been shown - to reduce target organ damage in organs such as the kidney, brain and heart, and - to decrease cardiovascular mortality and morbidity in patients with congestive - heart failure. Experimental data point to an influence of ACE inhibitors and ARBs - on the number and function of endothelial progenitor cells revealing additional - mechanisms of action of these drugs. The VALIANT trial has shown equivalent - effects of ARB valsartan and the ACE-inhibitor captopril in patients post - myocardial infarction, but the dual RAS-blockade, compared to monotherapy, did - not further reduce events. In secondary prevention, the most-recently published - ONTARGET study provides evidence that on top of a better tolerability - AT(1)-receptors antagonists are equal to ACE inhibitors in the prevention of - clinical endpoints like cardiovascular mortality and morbidity, myocardial - infarction and stroke. The combined RAS blockade, however, achieved no further - benefits in vascular high-risk patients and was associated with more adverse - events. In chronic heart failure, ValHeFT and CHARM-ADDED have shown that - combined RAS inhibition with ACE inhibitor and valsartan or candesartan reduced - morbidity and mortality in certain patient subgroups. Accumulating evidence also - points to benefits of the combination therapy in individuals with proteinuric - nephropathies. In conclusion, while combined RAS-inhibition is not generally - indicated in patients along the cardio-reno-vascular continuum, it has already - proven to be effective in heart failure patients with incomplete neuroendocrine - blockade. In secondary prevention, monotherapy with either RAS inhibitor is - equally efficacious. Furthermore, novel pharmacologic agents such as renin - inhibitors may prove useful in preventing common side effects of RAS blockade - such as angiotensin escape and AT(1)-receptor upregulation, giving clinicians - additional therapeutic tools to optimally treat the individual patient. -FAU - Werner, Christian -AU - Werner C -AD - Klinik für Innere Medizin III - Kardiologie, Angiologie und Internistische - Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany. -FAU - Baumhäkel, Magnus -AU - Baumhäkel M -FAU - Teo, Koon K -AU - Teo KK -FAU - Schmieder, Roland -AU - Schmieder R -FAU - Mann, Johannes -AU - Mann J -FAU - Unger, Thomas -AU - Unger T -FAU - Yusuf, Salim -AU - Yusuf S -FAU - Böhm, Michael -AU - Böhm M -LA - eng -PT - Journal Article -PT - Review -DEP - 20080503 -PL - Germany -TA - Clin Res Cardiol -JT - Clinical research in cardiology : official journal of the German Cardiac Society -JID - 101264123 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -SB - IM -MH - Angiotensin II Type 1 Receptor Blockers/*therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/*therapeutic use -MH - Cardiovascular Diseases/*drug therapy/mortality/physiopathology -MH - Endothelium/drug effects/physiology -MH - Humans -MH - Kidney/physiology -MH - Meta-Analysis as Topic -MH - *Patient Selection -MH - Renin-Angiotensin System/*drug effects/physiology -MH - Risk Factors -RF - 85 -EDAT- 2008/05/06 09:00 -MHDA- 2009/01/13 09:00 -CRDT- 2008/05/06 09:00 -PHST- 2004/01/23 00:00 [received] -PHST- 2008/04/10 00:00 [accepted] -PHST- 2008/05/06 09:00 [pubmed] -PHST- 2009/01/13 09:00 [medline] -PHST- 2008/05/06 09:00 [entrez] -AID - 10.1007/s00392-008-0668-3 [doi] -PST - ppublish -SO - Clin Res Cardiol. 2008 Jul;97(7):418-31. doi: 10.1007/s00392-008-0668-3. Epub - 2008 May 3. - -PMID- 19880848 -OWN - NLM -STAT- MEDLINE -DCOM- 20100330 -LR - 20091202 -IS - 1522-9645 (Electronic) -IS - 0195-668X (Linking) -VI - 30 -IP - 23 -DP - 2009 Dec -TI - Treating inflammation in atherosclerotic cardiovascular disease: emerging - therapies. -PG - 2838-44 -LID - 10.1093/eurheartj/ehp477 [doi] -AB - Atherosclerosis constitutes the underlying disease to the clinical manifestations - of myocardial infarction, stroke, and gangrene. Despite the success of statins, - prevention of clinical events of atherosclerosis remains a major challenge in - current-day cardiology. Research into the inflammatory nature of atherosclerosis - has led to improved mechanistic understanding of its pathogenesis and to the - identification of novel therapeutic targets discussed in this review. Recent - genetic and epidemiological data document shared pathologies of chronic - inflammatory diseases and atherosclerosis. Anti-inflammatory treatment regimens - used in these diseases, including tumor necrosis factor-alpha blockade, IL-1 - receptor antagonism, and leukotriene blockade may be beneficial also in patients - with coronary artery disease. Enhancing inherent atheroprotective immunity by - expansion of regulatory T cells may emerge as a future therapeutic strategy. - Immunization strategies directed against atherosclerosis-related antigens such as - epitopes within the low-density lipoprotein particle have been extensively - studied in animal models and may enter the clinical stage. Success of these novel - therapies will be critically dependent on the adequate identification of patients - and choice of appropriate clinical endpoints. -FAU - Klingenberg, Roland -AU - Klingenberg R -AD - Department of Cardiology, University Hospital Zurich, CH-8091 Zurich, - Switzerland. roland.klingenberg@usz.ch -FAU - Hansson, Göran K -AU - Hansson GK -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20091030 -PL - England -TA - Eur Heart J -JT - European heart journal -JID - 8006263 -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Leukotriene Antagonists) -RN - 0 (Leukotrienes) -RN - 0 (Receptors, Interleukin-1) -RN - 0 (Tumor Necrosis Factor-alpha) -SB - IM -MH - Anti-Inflammatory Agents/*therapeutic use -MH - Atherosclerosis/*drug therapy/immunology -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use -MH - Inflammation/drug therapy -MH - Leukocytes/immunology -MH - Leukotriene Antagonists/therapeutic use -MH - Leukotrienes/immunology -MH - Receptors, Interleukin-1/antagonists & inhibitors -MH - Tumor Necrosis Factor-alpha/antagonists & inhibitors -RF - 79 -EDAT- 2009/11/03 06:00 -MHDA- 2010/03/31 06:00 -CRDT- 2009/11/03 06:00 -PHST- 2009/11/03 06:00 [entrez] -PHST- 2009/11/03 06:00 [pubmed] -PHST- 2010/03/31 06:00 [medline] -AID - ehp477 [pii] -AID - 10.1093/eurheartj/ehp477 [doi] -PST - ppublish -SO - Eur Heart J. 2009 Dec;30(23):2838-44. doi: 10.1093/eurheartj/ehp477. Epub 2009 - Oct 30. - -PMID- 18373325 -OWN - NLM -STAT- MEDLINE -DCOM- 20090529 -LR - 20240718 -IS - 0160-9289 (Print) -IS - 1932-8737 (Electronic) -IS - 0160-9289 (Linking) -VI - 30 -IP - 2 Suppl 1 -DP - 2007 Feb -TI - The burden of angina pectoris and its complications [corrected]. -PG - I10-5 -AB - Between 10 to 30% of patients with coronary disease still suffer from symptoms of - angina pectoris in contemporary clinical practice. This article summarizes - analytic tools for measuring angina, as well as, its prevalence based on - community based surveys, registries and in randomized controlled trials. - Additionally, the impact of angina symptoms on patients' survival rates, - functional status, quality of life and health-related costs is reviewed. The - effectiveness of treatment, revascularization and medical therapies, on reducing - angina symptoms is also reviewed. -CI - Copyright (c) 2007 Wiley Periodicals, Inc. -FAU - Peterson, Eric -AU - Peterson E -AD - Duke University Medical Center, Duke Clinical Research Institute, Box 17969, - Durham, NC 27715, USA. peter016@mc.duke.edu -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Clin Cardiol -JT - Clinical cardiology -JID - 7903272 -SB - IM -MH - Acute Coronary Syndrome/epidemiology/*physiopathology/psychology -MH - Angina Pectoris/classification/epidemiology/*physiopathology/psychology -MH - Cost of Illness -MH - Humans -MH - Prevalence -MH - Prognosis -MH - Psychometrics -MH - Quality of Life -MH - Surveys and Questionnaires -MH - United States/epidemiology -PMC - PMC6652933 -EDAT- 2007/02/01 00:00 -MHDA- 2009/05/30 09:00 -PMCR- 2007/02/26 -CRDT- 2007/02/01 00:00 -PHST- 2007/02/01 00:00 [pubmed] -PHST- 2009/05/30 09:00 [medline] -PHST- 2007/02/01 00:00 [entrez] -PHST- 2007/02/26 00:00 [pmc-release] -AID - CLC20047 [pii] -AID - 10.1002/clc.20047 [doi] -PST - ppublish -SO - Clin Cardiol. 2007 Feb;30(2 Suppl 1):I10-5. doi: 10.1002/clc.20047. - -PMID- 19728749 -OWN - NLM -STAT- MEDLINE -DCOM- 20091013 -LR - 20211020 -IS - 1179-1969 (Electronic) -IS - 1170-229X (Linking) -VI - 26 -IP - 9 -DP - 2009 -TI - Role of angiotensin II type 1 receptor antagonists in the treatment of - hypertension in patients aged >or=65 years. -PG - 751-67 -LID - 10.2165/11316790-000000000-00000 [doi] -AB - Systolic blood pressure (SBP) increases with age, and hypertension affects - approximately two-thirds of adults in the US aged >60 years. Blood pressure (BP) - increases as a consequence of age-related structural changes in large arteries, - which lead to loss of elasticity and reduced vascular compliance. Increased pulse - wave velocity augments SBP, resulting in a high prevalence of isolated systolic - hypertension. Because age itself elevates cardiovascular risk, effective - treatment of hypertension in an older (aged >or=65 years) patient population - prevents many more events per 1000 patients treated than treatment of younger - hypertensive patients. Recommendations for treating hypertension are similar in - older patients compared with the general population. The Seventh Report of the - Joint National Committee on Detection, Prevention, Evaluation, and Treatment of - High Blood Pressure recommends target BP goals of <140/90 mmHg for patients with - uncomplicated hypertension, and <130/80 mmHg for those with diabetes mellitus or - renal disease. Recent guidelines and position papers have extended these - aggressive treatment goals to include patients with coronary artery disease, - other types of vascular disease and heart failure. Randomized clinical trials - have demonstrated the efficacy of calcium channel antagonists (calcium channel - blockers [CCBs]), low-dose diuretics, ACE inhibitors and angiotensin II type 1 - receptor antagonists (angiotensin receptor blockers [ARBs]) in reducing the risk - of stroke and other adverse cardiovascular outcomes in older patients; - beta-adrenoceptor antagonists are less effective in terms of endpoint reduction. - The majority of older patients require two or more drugs to achieve BP goals. - Despite active treatment, half of these patients do not achieve target BP, in - part because of the reluctance of physicians to intensify treatment, a phenomenon - referred to as 'clinical inertia'. ARBs are effective antihypertensive agents in - older patients and have been shown to reduce cardiovascular endpoints in patients - with hypertension, diabetic nephropathy, cerebrovascular disease and heart - failure. ARBs produce additive BP reduction when combined with diuretics or CCBs. - They also have the advantage of placebo-like tolerability, and this contributes - favourably to patient compliance with long-term treatment, which is a - prerequisite for reducing morbidity and mortality. -FAU - Gradman, Alan H -AU - Gradman AH -AD - Division of Cardiovascular Diseases, The Western Pennsylvania Hospital, - Pittsburgh, Pennsylvania 15224, USA. gradmanmd@aol.com -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - New Zealand -TA - Drugs Aging -JT - Drugs & aging -JID - 9102074 -RN - 0 (Angiotensin II Type 1 Receptor Blockers) -RN - 0 (Antihypertensive Agents) -SB - IM -MH - Aged -MH - Aged, 80 and over -MH - Aging/physiology -MH - Angiotensin II Type 1 Receptor Blockers/adverse effects/*therapeutic use -MH - Antihypertensive Agents/adverse effects/*therapeutic use -MH - Drug Therapy, Combination -MH - Female -MH - Geriatrics -MH - Humans -MH - Hypertension/*drug therapy -MH - Male -MH - Treatment Outcome -RF - 121 -EDAT- 2009/09/05 06:00 -MHDA- 2009/10/14 06:00 -CRDT- 2009/09/05 06:00 -PHST- 2009/09/05 06:00 [entrez] -PHST- 2009/09/05 06:00 [pubmed] -PHST- 2009/10/14 06:00 [medline] -AID - 3 [pii] -AID - 10.2165/11316790-000000000-00000 [doi] -PST - ppublish -SO - Drugs Aging. 2009;26(9):751-67. doi: 10.2165/11316790-000000000-00000. - -PMID- 23592806 -OWN - NLM -STAT- MEDLINE -DCOM- 20140130 -LR - 20250529 -IS - 1755-3245 (Electronic) -IS - 0008-6363 (Linking) -VI - 99 -IP - 2 -DP - 2013 Jul 15 -TI - The effects of stenting on shear stress: relevance to endothelial injury and - repair. -PG - 269-75 -LID - 10.1093/cvr/cvt090 [doi] -AB - Stent deployment following balloon angioplasty is used routinely to treat - coronary artery disease. These interventions cause damage and loss of endothelial - cells (EC), and thus promote in-stent thrombosis and restenosis. Injured arteries - are repaired (intrinsically) by locally derived EC and by circulating endothelial - progenitor cells which migrate and proliferate to re-populate denuded regions. - However, re-endothelialization is not always complete and often dysfunctional. - Moreover, the molecular and biomechanical mechanisms that control EC repair and - function in stented segments are poorly understood. Here, we propose that stents - modify endothelial repair processes, in part, by altering fluid shear stress, a - mechanical force that influences EC migration and proliferation. A more detailed - understanding of the biomechanical processes that control endothelial healing - would provide a platform for the development of novel therapeutic approaches to - minimize damage and promote vascular repair in stented arteries. -FAU - Van der Heiden, Kim -AU - Van der Heiden K -AD - Biomedical Engineering, Department Cardiology, ErasmusMC, Rotterdam, The - Netherlands. -FAU - Gijsen, Frank J H -AU - Gijsen FJ -FAU - Narracott, Andrew -AU - Narracott A -FAU - Hsiao, Sarah -AU - Hsiao S -FAU - Halliday, Ian -AU - Halliday I -FAU - Gunn, Julian -AU - Gunn J -FAU - Wentzel, Jolanda J -AU - Wentzel JJ -FAU - Evans, Paul C -AU - Evans PC -LA - eng -GR - PG/09/088/28058/BHF_/British Heart Foundation/United Kingdom -GR - RG/13/1/30042/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130415 -PL - England -TA - Cardiovasc Res -JT - Cardiovascular research -JID - 0077427 -SB - IM -MH - Angioplasty, Balloon/*adverse effects/*instrumentation -MH - Animals -MH - Biomechanical Phenomena -MH - Cell Movement -MH - Cell Proliferation -MH - Computer Simulation -MH - Constriction, Pathologic -MH - Endothelium, Vascular/*injuries/metabolism/pathology/physiopathology -MH - *Hemodynamics -MH - Humans -MH - *Mechanotransduction, Cellular -MH - Models, Cardiovascular -MH - *Regeneration -MH - Regional Blood Flow -MH - *Stents -MH - Stress, Mechanical -MH - Thrombosis/etiology/pathology/physiopathology -MH - Vascular System Injuries/*etiology/metabolism/pathology/physiopathology -OTO - NOTNLM -OT - Endothelial cell -OT - Shear stress -OT - Stent -OT - Vascular repair -EDAT- 2013/04/18 06:00 -MHDA- 2014/01/31 06:00 -CRDT- 2013/04/18 06:00 -PHST- 2013/04/18 06:00 [entrez] -PHST- 2013/04/18 06:00 [pubmed] -PHST- 2014/01/31 06:00 [medline] -AID - cvt090 [pii] -AID - 10.1093/cvr/cvt090 [doi] -PST - ppublish -SO - Cardiovasc Res. 2013 Jul 15;99(2):269-75. doi: 10.1093/cvr/cvt090. Epub 2013 Apr - 15. - -PMID- 21962238 -OWN - NLM -STAT- MEDLINE -DCOM- 20120521 -LR - 20250529 -IS - 1879-1484 (Electronic) -IS - 0021-9150 (Linking) -VI - 220 -IP - 2 -DP - 2012 Feb -TI - Phosphate: the new cholesterol? The role of the phosphate axis in non-uremic - vascular disease. -PG - 310-8 -LID - 10.1016/j.atherosclerosis.2011.09.002 [doi] -AB - Higher serum phosphate levels within the normal range are associated with - substantially increased risk of cardiovascular disease events. Whether this - reflects a causative relationship is unknown. Phosphate-responsive hormones - (fibroblast growth factor-23, parathyroid hormone and calcitriol) are also - predictors of cardiovascular mortality in populations without kidney disease or - recognised disturbances of bone mineral metabolism. The high bioavailable - phosphate content of Western diets may contribute to this apparent discrepancy - between 'normal' and optimal phosphate axis parameters. Although uremic - hyperphosphatemia is recognised to cause vascular medial calcification, this does - not readily explain the association of higher-normal phosphate with common - athero-occlusive phenomena. The phosphate axis may in fact play a role in - atherogenesis; observational data link higher levels of phosphate and fibroblast - growth factor-23 with coronary atheroma burden, whilst dietary phosphate - supplementation accelerates atherosclerosis in a mouse model. In vitro studies - show adverse effects of phosphate increases on both vascular smooth muscle cells - and endothelium, though these observations have not yet been extended to - phosphate increments within the normal range. Receptors for phosphate-responsive - hormones are present throughout the cardiovascular system and may mediate - atherogenic effects. Since interventions are already available to manipulate the - phosphate axis, this is an important issue. If an atherogenic role for phosphate - exposure is demonstrated then phosphate binders could become the new statins. -CI - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. -FAU - Ellam, Timothy J -AU - Ellam TJ -AD - Department of Cardiovascular Science, Sheffield University, Medical School, Beech - Hill Road, Sheffield S10 2RX, United Kingdom. T.Ellam@Sheffield.ac.uk -FAU - Chico, Timothy J A -AU - Chico TJ -LA - eng -GR - FS/11/74/29015/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Review -DEP - 20110909 -PL - Ireland -TA - Atherosclerosis -JT - Atherosclerosis -JID - 0242543 -RN - 0 (Chelating Agents) -RN - 0 (Parathyroid Hormone) -RN - 0 (Phosphates) -RN - 0 (Phosphorus, Dietary) -RN - 1406-16-2 (Vitamin D) -RN - 62031-54-3 (Fibroblast Growth Factors) -RN - 7Q7P4S7RRE (Fibroblast Growth Factor-23) -RN - 97C5T2UQ7J (Cholesterol) -RN - SY7Q814VUP (Calcium) -SB - IM -MH - Animals -MH - Blood Vessels/drug effects/*metabolism/physiopathology -MH - Bone and Bones/metabolism -MH - Calcium/metabolism -MH - Chelating Agents/therapeutic use -MH - Cholesterol/blood/*metabolism -MH - Fibroblast Growth Factor-23 -MH - Fibroblast Growth Factors/metabolism -MH - Humans -MH - Parathyroid Hormone/metabolism -MH - Phosphates/blood/*metabolism -MH - Phosphorus, Dietary/metabolism -MH - *Signal Transduction/drug effects -MH - Vascular Diseases/blood/drug therapy/*metabolism/physiopathology -MH - Vitamin D/metabolism -EDAT- 2011/10/04 06:00 -MHDA- 2012/05/23 06:00 -CRDT- 2011/10/04 06:00 -PHST- 2011/08/02 00:00 [received] -PHST- 2011/09/01 00:00 [revised] -PHST- 2011/09/02 00:00 [accepted] -PHST- 2011/10/04 06:00 [entrez] -PHST- 2011/10/04 06:00 [pubmed] -PHST- 2012/05/23 06:00 [medline] -AID - S0021-9150(11)00858-6 [pii] -AID - 10.1016/j.atherosclerosis.2011.09.002 [doi] -PST - ppublish -SO - Atherosclerosis. 2012 Feb;220(2):310-8. doi: - 10.1016/j.atherosclerosis.2011.09.002. Epub 2011 Sep 9. - -PMID- 21235458 -OWN - NLM -STAT- MEDLINE -DCOM- 20120529 -LR - 20190918 -IS - 1873-4316 (Electronic) -IS - 1389-2010 (Linking) -VI - 12 -IP - 9 -DP - 2011 Sep -TI - Exercise-induced modulation of endothelial nitric oxide production. -PG - 1375-84 -AB - In the arterial wall nitric oxide (NO) is the key transmitter for - endothelium-dependent regulation of vascular tone. It is produced in intact - endothelial cells by endothelial NO synthase (eNOS) as the key enzyme from - L-arginine. Endothelial NO generation is highly regulated by mechanical, humoral, - and metabolic factors. The regulation of NO synthesis occurs at different levels: - ENOS gene polymorphisms are related to eNOS expression and activity and may - potentially increase coronary event rate, mRNA expression is influenced by - estrogen status and shear stress, mRNA stability is enhanced by vascular - endothelial growth factor (VEGF), and final enzyme activity is regulated by the - phosphorylation status at serine/threonine residues. Released from endothelial - cells NO is rapidly transported to the neighboring vascular smooth muscle cells - (VSMCs), where it induces the production of cGMP as a second messenger. CGMP in - turn increases Ca2+ uptake into intracellular calcium stores thereby lowering - [Ca2+]i and inducing VSMC relaxation and vasodilation. On its way to the VSMCs NO - may be prematurely degraded by reactive oxygen species. On the other hand, - chronic endurance exercise with regular bouts of increased laminar flow along the - endothelium has the potential to increase eNOS mRNA expression and - phosphorylation via AKT (protein kinase B) and to reduce oxidative stress by - improving antioxidative protection. The growing knowledge about the complex - regulation of NO synthesis and degradation in cardiovascular diseases and its - response to exercise has led to a new understanding of the protective effects of - long-term habitual physical activity against atherosclerotic heart disease and - vascular aging. -FAU - Gielen, Stephan -AU - Gielen S -AD - Department of Internal Medicine/Cardiology, University of Leipzig - Heart Center, - Strumpellstrabe 39, 04289 Leipzig, Germany. stephan.gielen@medizin.uni-leipzig.de -FAU - Sandri, Marcus -AU - Sandri M -FAU - Erbs, Sandra -AU - Erbs S -FAU - Adams, Volker -AU - Adams V -LA - eng -PT - Journal Article -PT - Review -PL - Netherlands -TA - Curr Pharm Biotechnol -JT - Current pharmaceutical biotechnology -JID - 100960530 -RN - 31C4KY9ESH (Nitric Oxide) -RN - EC 1.14.13.39 (Nitric Oxide Synthase Type III) -SB - IM -MH - Animals -MH - Endothelial Cells/physiology -MH - Endothelium, Vascular/cytology/physiology -MH - Exercise/*physiology -MH - Humans -MH - Nitric Oxide/physiology -MH - Nitric Oxide Synthase Type III/*physiology -MH - Stem Cells/cytology -EDAT- 2011/01/18 06:00 -MHDA- 2012/05/30 06:00 -CRDT- 2011/01/18 06:00 -PHST- 2010/06/02 00:00 [received] -PHST- 2010/08/09 00:00 [revised] -PHST- 2010/08/19 00:00 [accepted] -PHST- 2011/01/18 06:00 [entrez] -PHST- 2011/01/18 06:00 [pubmed] -PHST- 2012/05/30 06:00 [medline] -AID - BSP/CPB/E-Pub/-00058-12-5 [pii] -AID - 10.2174/138920111798281063 [doi] -PST - ppublish -SO - Curr Pharm Biotechnol. 2011 Sep;12(9):1375-84. doi: 10.2174/138920111798281063. - -PMID- 28582143 -OWN - NLM -STAT- PubMed-not-MEDLINE -LR - 20191120 -IS - 2211-7466 (Electronic) -IS - 2211-7458 (Linking) -VI - 2 -IP - 2 -DP - 2013 Apr -TI - Adjunctive Pharmacotherapy for Thrombotic Coronary Lesions. -PG - 375-387 -LID - S2211-7458(12)00158-7 [pii] -LID - 10.1016/j.iccl.2012.11.003 [doi] -AB - Patients with unstable coronary syndromes are often found to have intracoronary - thrombus on angiography. Despite advancements in catheter-based treatments for - coronary disease, these lesions remain challenging, as percutaneous coronary - intervention of thrombus-containing lesions may be associated with worse - outcomes. This article reviews the literature on adjunctive pharmacotherapy in - the treatment of thrombotic coronary lesions with special focus on ST-segment - elevation myocardial infarction, lesions with high thrombus burden, and saphenous - vein graft intervention. -CI - Copyright © 2013 Elsevier Inc. All rights reserved. -FAU - Huang, Pei-Hsiu -AU - Huang PH -AD - Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard - Medical School, 75 Francis Street, Boston, MA 02115, USA. -FAU - Bhatt, Deepak L -AU - Bhatt DL -AD - Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard - Medical School, 75 Francis Street, Boston, MA 02115, USA; Integrated - Interventional Cardiovascular Program, Cardiovascular Division, VA Boston - Healthcare System, 1400 VFW Parkway, Boston, MA 02132, USA. Electronic address: - dlbhattmd@post.harvard.edu. -LA - eng -PT - Journal Article -PT - Review -DEP - 20130327 -PL - Netherlands -TA - Interv Cardiol Clin -JT - Interventional cardiology clinics -JID - 101615153 -OTO - NOTNLM -OT - Glycoprotein IIb/IIIa inhibitors -OT - Intracoronary thrombus -OT - Percutaneous coronary intervention -OT - Thrombolytic therapy -EDAT- 2013/04/01 00:00 -MHDA- 2013/04/01 00:01 -CRDT- 2017/06/06 06:00 -PHST- 2017/06/06 06:00 [entrez] -PHST- 2013/04/01 00:00 [pubmed] -PHST- 2013/04/01 00:01 [medline] -AID - S2211-7458(12)00158-7 [pii] -AID - 10.1016/j.iccl.2012.11.003 [doi] -PST - ppublish -SO - Interv Cardiol Clin. 2013 Apr;2(2):375-387. doi: 10.1016/j.iccl.2012.11.003. Epub - 2013 Mar 27. - -PMID- 23932901 -OWN - NLM -STAT- MEDLINE -DCOM- 20140428 -LR - 20161125 -IS - 1590-3729 (Electronic) -IS - 0939-4753 (Linking) -VI - 23 -IP - 9 -DP - 2013 Sep -TI - Managing the residual cardiovascular disease risk associated with HDL-cholesterol - and triglycerides in statin-treated patients: a clinical update. -PG - 799-807 -LID - S0939-4753(13)00120-8 [pii] -LID - 10.1016/j.numecd.2013.05.002 [doi] -AB - Cardiovascular disease (CVD) is a significant cause of death in Europe. In - addition to patients with proven CVD, those with type 2 diabetes (T2D) are at a - particularly high-risk of CVD and associated mortality. Treatment for - dyslipidaemia, a principal risk factor for CVD, remains a healthcare priority; - evidence supports the reduction of low-density lipoprotein cholesterol (LDL-C) as - the primary objective of dyslipidaemia management. While statins are the - treatment of choice for lowering LDL-C in the majority of patients, including - those with T2D, many patients retain a high CVD risk despite achieving the - recommended LDL-C targets with statins. This 'residual risk' is mainly due to - elevated triglyceride (TG) and low high-density lipoprotein cholesterol (HDL-C) - levels. Following statin therapy optimisation additional pharmacotherapy should - be considered as part of a multifaceted approach to risk reduction. Fibrates - (especially fenofibrate) are the principal agents recommended for add-on therapy - to treat elevated TG or low HDL-C levels. Currently, the strongest evidence of - benefit is for the addition of fenofibrate to statin treatment in high-risk - patients with T2D and dyslipidaemia. An alternative approach is the addition of - agents to reduce LDL-C beyond the levels attainable with statin monotherapy. - Here, addition of fibrates and niacin to statin therapy is discussed, and novel - approaches being developed for HDL-C and TG management, including cholesteryl - ester transfer protein inhibitors, Apo A-1 analogues, mipomersen, lomitapide and - monoclonal antibodies against PCSK9, are reviewed. -CI - Copyright © 2013 Elsevier B.V. All rights reserved. -FAU - Reiner, Z -AU - Reiner Z -AD - Department of Internal Medicine, University Hospital Center Zagreb, School of - Medicine, University of Zagreb, Kispaticeva 12, 10 000 Zagreb, Croatia. - Electronic address: zreiner@kbc-zagreb.hr. -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20130809 -PL - Netherlands -TA - Nutr Metab Cardiovasc Dis -JT - Nutrition, metabolism, and cardiovascular diseases : NMCD -JID - 9111474 -RN - 0 (Antibodies, Monoclonal) -RN - 0 (Anticholesteremic Agents) -RN - 0 (Apolipoprotein A-I) -RN - 0 (BMS201038) -RN - 0 (Benzimidazoles) -RN - 0 (CETP protein, human) -RN - 0 (Cholesterol Ester Transfer Proteins) -RN - 0 (Cholesterol, HDL) -RN - 0 (Fibric Acids) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Oligonucleotides) -RN - 0 (Triglycerides) -RN - 2679MF687A (Niacin) -RN - 9GJ8S4GU0M (mipomersen) -RN - EC 3.4.21.- (PCSK9 protein, human) -RN - EC 3.4.21.- (Proprotein Convertase 9) -RN - EC 3.4.21.- (Proprotein Convertases) -RN - EC 3.4.21.- (Serine Endopeptidases) -SB - IM -MH - Antibodies, Monoclonal/therapeutic use -MH - Anticholesteremic Agents/therapeutic use -MH - Apolipoprotein A-I/therapeutic use -MH - Benzimidazoles/therapeutic use -MH - Cardiovascular Diseases/complications/*drug therapy -MH - Cholesterol Ester Transfer Proteins/antagonists & inhibitors/metabolism -MH - Cholesterol, HDL/*blood -MH - Diabetes Mellitus, Type 2/complications/drug therapy -MH - Dyslipidemias/complications/drug therapy -MH - Fibric Acids/therapeutic use -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Niacin/therapeutic use -MH - Oligonucleotides/therapeutic use -MH - Proprotein Convertase 9 -MH - Proprotein Convertases/antagonists & inhibitors/metabolism -MH - Risk Factors -MH - Serine Endopeptidases/metabolism -MH - Triglycerides/*blood -OTO - NOTNLM -OT - ACCORD -OT - AIM-HIGH -OT - ARBITER -OT - Action to Control Cardiovascular Risk in Diabetes -OT - Arterial Biology for the Investigation of the Treatment Effects of Reducing - Cholesterol -OT - Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High - Triglycerides and Impact on Global Health Outcomes -OT - BIP -OT - Bezafibrate Infarction Prevention -OT - CTT -OT - Cardiovascular diseases -OT - Cholesterol Treatment Trialists -OT - EAS -OT - ERASE -OT - ESC -OT - Effect of reconstituted HDL on Atherosclerosis-Safety and Efficacy -OT - European Atherosclerosis Society -OT - European Society of Cardiology -OT - FIELD -OT - Fenofibrate Intervention and Event Lowering in Diabetes -OT - Fibrates -OT - HPS2-THRIVE -OT - Heart Protection Study 2: Treatment of HDL to Reduce the Incidence of Vascular - Events -OT - Hypertriglyceridaemia -OT - ILLUMINATE -OT - Investigation of Lipid Level Management to Understand its Impact in - Atherosclerotic Events -OT - Nicotinic acid -OT - SCORE -OT - Statins -OT - Study of the Effect of Dalcetrapib on Atherosclerotic Disease in Patients with - Coronary Artery Disease -OT - Systemic Coronary Risk Estimation -OT - Triglycerides -OT - dal-OUTCOMES -EDAT- 2013/08/13 06:00 -MHDA- 2014/04/29 06:00 -CRDT- 2013/08/13 06:00 -PHST- 2012/11/02 00:00 [received] -PHST- 2013/04/16 00:00 [revised] -PHST- 2013/05/09 00:00 [accepted] -PHST- 2013/08/13 06:00 [entrez] -PHST- 2013/08/13 06:00 [pubmed] -PHST- 2014/04/29 06:00 [medline] -AID - S0939-4753(13)00120-8 [pii] -AID - 10.1016/j.numecd.2013.05.002 [doi] -PST - ppublish -SO - Nutr Metab Cardiovasc Dis. 2013 Sep;23(9):799-807. doi: - 10.1016/j.numecd.2013.05.002. Epub 2013 Aug 9. - -PMID- 21821533 -OWN - NLM -STAT- MEDLINE -DCOM- 20120213 -LR - 20250529 -IS - 1940-4034 (Electronic) -IS - 1074-2484 (Linking) -VI - 16 -IP - 3-4 -DP - 2011 Sep-Dec -TI - Remote ischemic conditioning: a clinical trial's update. -PG - 304-12 -LID - 10.1177/1074248411411711 [doi] -AB - Coronary artery disease (CAD) is the leading cause of death and disability - worldwide, and early and successful restoration of myocardial reperfusion - following an ischemic event is the most effective strategy to reduce final - infarct size and improve clinical outcome. This process can, however, induce - further myocardial damage, namely acute myocardial ischemia-reperfusion injury - (IRI) and worsen clinical outcome. Therefore, novel therapeutic strategies are - required to protect the myocardium against IRI in patients with CAD. In this - regard, the endogenous cardioprotective phenomenon of "ischemic conditioning," in - which the heart is put into a protected state by subjecting it to one or more - brief nonlethal episodes of ischemia and reperfusion, has the potential to - attenuate myocardial injury during acute IRI. Intriguingly, the heart can be - protected in this manner by applying the "ischemic conditioning" stimulus to an - organ or tissue remote from the heart (termed remote ischemic conditioning or - RIC). Furthermore, the discovery that RIC can be noninvasively applied using a - blood pressure cuff on the upper arm to induce brief episodes of nonlethal - ischemia and reperfusion in the forearm has greatly facilitated the translation - of RIC into the clinical arena. Several recently published proof-of-concept - clinical studies have reported encouraging results with RIC, and large - multicenter randomized clinical trials are now underway to investigate whether - this simple noninvasive and virtually cost-free intervention has the potential to - improve clinical outcomes in patients with CAD. In this review article, we - provide an update of recently published and ongoing clinical trials in the field - of RIC. -FAU - Candilio, Luciano -AU - Candilio L -AD - The Hatter Cardiovascular Institute, University College London Hospital and - Medical School, London, UK. -FAU - Hausenloy, Derek J -AU - Hausenloy DJ -FAU - Yellon, Derek M -AU - Yellon DM -LA - eng -GR - MC_G1002673/MRC_/Medical Research Council/United Kingdom -GR - RG/03/007/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - J Cardiovasc Pharmacol Ther -JT - Journal of cardiovascular pharmacology and therapeutics -JID - 9602617 -RN - 0 (Cardiotonic Agents) -SB - IM -MH - Cardiotonic Agents/*pharmacology -MH - Clinical Trials as Topic -MH - Female -MH - Humans -MH - Ischemic Preconditioning, Myocardial/*methods -MH - Male -MH - Myocardial Infarction/physiopathology/*therapy -MH - Myocardial Reperfusion Injury/epidemiology/mortality/physiopathology/*therapy -EDAT- 2011/08/09 06:00 -MHDA- 2012/02/14 06:00 -CRDT- 2011/08/09 06:00 -PHST- 2011/08/09 06:00 [entrez] -PHST- 2011/08/09 06:00 [pubmed] -PHST- 2012/02/14 06:00 [medline] -AID - 16/3-4/304 [pii] -AID - 10.1177/1074248411411711 [doi] -PST - ppublish -SO - J Cardiovasc Pharmacol Ther. 2011 Sep-Dec;16(3-4):304-12. doi: - 10.1177/1074248411411711. - -PMID- 21081794 -OWN - NLM -STAT- MEDLINE -DCOM- 20110621 -LR - 20210526 -IS - 1899-1505 (Electronic) -IS - 0867-5910 (Linking) -VI - 61 -IP - 5 -DP - 2010 Oct -TI - Brain and cardiovascular diseases: common neurogenic background of - cardiovascular, metabolic and inflammatory diseases. -PG - 509-21 -AB - In spite of significant progress in pharmacotherapy the incidence of newly - diagnosed cases of cardiovascular diseases and cardiovascular morbidity is - alarmingly high. Treatment of hypertension or heart failure still remains a - serious challenge. Continuous attempts are made to identify the mechanisms that - decide about susceptibility to pathogenic factors, and to determine effectiveness - of a specific therapeutic approach. Coincidence of cardiovascular diseases with - metabolic disorders and obesity has initiated intensive research for their common - background. In the recent years increasing attention has been drawn to - disproportionately greater number of depressive disorders and susceptibility to - stress in patients with coronary artery disease. An opposite relationship, i.e. a - greater number of sudden cardiovascular complications in patients with - depression, has been also postulated. Progress in functional neuroanatomy and - neurochemistry provided new information about the neural network responsible for - regulation of cardiovascular functions, metabolism and emotionality in health and - under pathological conditions. In this review we will focus on the role of - neuromodulators and neurotransmitters engaged in regulation of the cardiovascular - system, neuroendocrine and metabolic functions in health and in pathogenesis of - cardiovascular diseases and obesity. Among them are classical neurotransmitters - (epinephrine and norepinephrine, serotonin, GABA), classical (CRH, vasopressin, - neuropeptide Y) and newly discovered (orexins, apelin, leptin IL-1beta, - TNF-alpha, ghrelin) neuropeptides, gasotransmitters, eicozanoids, - endocannabinoids, and some other compounds involved in regulation of - neuroendocrine, sympatho-adrenal and parasympathetic nervous systems. Special - attention is drawn to those factors which play a role in immunology and - inflammatory processes. Interaction between various - neurotransmitter/neuromodulatory systems which may be involved in integration of - metabolic and cardiovascular functions is analyzed. The survey gives evidence for - significant disturbances in release or action of the same mediators in - hypertension heart failure, obesity, diabetes mellitus, metabolic syndrome, - starvation, chronic stress, depression and other psychiatric disorders. With - regard to the pathogenic background of the cardiovascular diseases especially - valuable are the studies showing inappropriate function of angiotensin peptides, - vasopressin, CRH, apelin, cytokines and orexins in chronic stress, cardiovascular - and metabolic diseases. The studies surveyed in this review suggest that multiple - brain mechanisms interact together sharing the same neural circuits responsible - for adjustment of function of the cardiovascular system and metabolism to current - needs. -FAU - Szczepanska-Sadowska, E -AU - Szczepanska-Sadowska E -AD - Department of Experimental and Clinical Physiology, The Medical University of - Warsaw, Warsaw, Poland. eszczepanska@wum.edu.pl -FAU - Cudnoch-Jedrzejewska, A -AU - Cudnoch-Jedrzejewska A -FAU - Ufnal, M -AU - Ufnal M -FAU - Zera, T -AU - Zera T -LA - eng -PT - Journal Article -PT - Review -PL - Poland -TA - J Physiol Pharmacol -JT - Journal of physiology and pharmacology : an official journal of the Polish - Physiological Society -JID - 9114501 -RN - 0 (Neurotransmitter Agents) -SB - IM -MH - Animals -MH - Brain/*physiopathology -MH - Cardiovascular Diseases/*physiopathology -MH - Cardiovascular Physiological Phenomena -MH - Cardiovascular System/physiopathology -MH - Depressive Disorder/physiopathology -MH - Female -MH - Heart Failure/physiopathology -MH - Humans -MH - Hypertension/physiopathology -MH - Inflammation/*physiopathology -MH - Male -MH - Metabolic Syndrome/*physiopathology -MH - Neurosecretory Systems/*physiopathology -MH - Neurotransmitter Agents/*physiology -EDAT- 2010/11/18 06:00 -MHDA- 2011/06/22 06:00 -CRDT- 2010/11/18 06:00 -PHST- 2010/08/12 00:00 [received] -PHST- 2010/09/24 00:00 [accepted] -PHST- 2010/11/18 06:00 [entrez] -PHST- 2010/11/18 06:00 [pubmed] -PHST- 2011/06/22 06:00 [medline] -PST - ppublish -SO - J Physiol Pharmacol. 2010 Oct;61(5):509-21. - -PMID- 20656213 -OWN - NLM -STAT- MEDLINE -DCOM- 20110426 -LR - 20220310 -IS - 1873-2615 (Electronic) -IS - 1050-1738 (Linking) -VI - 20 -IP - 2 -DP - 2010 Feb -TI - The long pentraxin PTX3: a modulator of the immunoinflammatory response in - atherosclerosis and cardiovascular diseases. -PG - 35-40 -LID - 10.1016/j.tcm.2010.03.005 [doi] -AB - Innate and adaptive immune responses participate in atherosclerosis. Pentraxins, - an essential component of the humoral arm of innate immunity, are a superfamily - of acute phase proteins highly conserved during evolution and can be classified - as short pentraxins such as C-reactive protein (CRP) and long pentraxins such as - PTX3. The latter has an unrelated, long N-terminal domain coupled to the - C-terminal pentraxin domain and differs from CRP in gene organization, cellular - source, and recognized ligands. PTX3 in humans, like CRP, is a marker of - atherosclerosis and correlates with the risk of developing vascular events. - Although CRP sequence and regulation have not been conserved during evolution - between mouse and man, the conservation of sequence, gene organization, and - regulation of PTX3 in evolution enables one to address the question regarding its - pathophysiologic roles in genetically modified mice. Deficiency of PTX3 is - associated with increased heart damage with a greater no-reflow area and - increased inflammatory response in a model of acute myocardial infarction (MI) - caused by coronary artery ligation. More recently, deficiency of PTX3 on an - apolipoprotein E knockout background was associated with increased - atherosclerosis, macrophage accumulation within the plaque, and a more pronounced - inflammatory profile in the vascular wall. Although these observations point to a - cardiovascular protective effect of PTX3, they also suggest the possibility that - the increased levels of PTX3 in subjects with cardiovascular disease (CVD) may - reflect a protective physiologic response that correlates with the severity of - the disease. In summary, data that are accumulating suggest that the increase of - pentraxins in atherosclerosis could not be regarded as a harmful response but - rather a further attempt to protection of our body. -CI - Copyright (c) 2010 Elsevier Inc. All rights reserved. -FAU - Norata, Giuseppe Danilo -AU - Norata GD -AD - Department of Pharmacological Sciences, Università di Milano, 20133 Milan, Italy. - danilo.norata@unimi.it -FAU - Garlanda, Cecilia -AU - Garlanda C -FAU - Catapano, Alberico Luigi -AU - Catapano AL -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Trends Cardiovasc Med -JT - Trends in cardiovascular medicine -JID - 9108337 -RN - 0 (Biomarkers) -RN - 0 (Serum Amyloid P-Component) -RN - 148591-49-5 (PTX3 protein) -RN - 9007-41-4 (C-Reactive Protein) -SB - IM -MH - Animals -MH - Atherosclerosis/diagnosis/*immunology/pathology/prevention & control -MH - Biomarkers/blood -MH - C-Reactive Protein/genetics/metabolism/*physiology -MH - Cardiovascular Diseases/diagnosis/immunology/pathology -MH - Humans -MH - Inflammation -MH - Mice -MH - Serum Amyloid P-Component/genetics/metabolism/*physiology -EDAT- 2010/07/27 06:00 -MHDA- 2011/04/27 06:00 -CRDT- 2010/07/27 06:00 -PHST- 2010/07/27 06:00 [entrez] -PHST- 2010/07/27 06:00 [pubmed] -PHST- 2011/04/27 06:00 [medline] -AID - S1050-1738(10)00036-8 [pii] -AID - 10.1016/j.tcm.2010.03.005 [doi] -PST - ppublish -SO - Trends Cardiovasc Med. 2010 Feb;20(2):35-40. doi: 10.1016/j.tcm.2010.03.005. - -PMID- 20802505 -OWN - NLM -STAT- MEDLINE -DCOM- 20110217 -LR - 20221115 -IS - 1745-7254 (Electronic) -IS - 1671-4083 (Print) -IS - 1671-4083 (Linking) -VI - 31 -IP - 10 -DP - 2010 Oct -TI - Arterial stiffness: a brief review. -PG - 1267-76 -LID - 10.1038/aps.2010.123 [doi] -AB - Physical stiffening of the large arteries is the central paradigm of vascular - aging. Indeed, stiffening in the larger central arterial system, such as the - aortic tree, significantly contributes to cardiovascular diseases in older - individuals and is positively associated with systolic hypertension, coronary - artery disease, stroke, heart failure and atrial fibrillation, which are the - leading causes of mortality in the developed countries and also in the developing - world as estimated in 2010 by World Health Organizations. Thus, better, less - invasive and more accurate measures of arterial stiffness have been developed, - which prove useful as diagnostic indices, pathophysiological markers and - predictive indicators of disease. This article presents a review of the - structural determinants of vascular stiffening, its pathophysiologic determinants - and its implications for vascular research and medicine. A critical discussion of - new techniques for assessing vascular stiffness is also presented. -FAU - Shirwany, Najeeb A -AU - Shirwany NA -AD - Department of Medicine, University of Oklahoma Health Science Center, Oklahoma - City, 73104, USA. -FAU - Zou, Ming-hui -AU - Zou MH -LA - eng -GR - HL074399/HL/NHLBI NIH HHS/United States -GR - R01 HL089920/HL/NHLBI NIH HHS/United States -GR - HL080499/HL/NHLBI NIH HHS/United States -GR - HL079584/HL/NHLBI NIH HHS/United States -GR - R01 HL079584/HL/NHLBI NIH HHS/United States -GR - R01 HL080499/HL/NHLBI NIH HHS/United States -GR - R01 HL096032/HL/NHLBI NIH HHS/United States -GR - HL096032/HL/NHLBI NIH HHS/United States -GR - R01 HL074399/HL/NHLBI NIH HHS/United States -GR - HL089920/HL/NHLBI NIH HHS/United States -GR - R01 HL110488/HL/NHLBI NIH HHS/United States -GR - R01 HL105157/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20100830 -PL - United States -TA - Acta Pharmacol Sin -JT - Acta pharmacologica Sinica -JID - 100956087 -RN - 0 (Insulin) -RN - IY9XDZ35W2 (Glucose) -SB - IM -MH - Aging/physiology -MH - Animals -MH - Arteries/metabolism/*physiopathology -MH - Cardiovascular Diseases/genetics/metabolism/*physiopathology -MH - Diagnostic Techniques, Cardiovascular -MH - Diet -MH - *Elasticity -MH - Endothelium, Vascular/physiopathology -MH - Glucose/physiology -MH - Humans -MH - Insulin/physiology -MH - Neurosecretory Systems/physiopathology -MH - Risk Factors -MH - *Vascular Resistance -PMC - PMC3078647 -MID - NIHMS262177 -EDAT- 2010/08/31 06:00 -MHDA- 2011/02/18 06:00 -PMCR- 2010/10/01 -CRDT- 2010/08/31 06:00 -PHST- 2010/08/31 06:00 [entrez] -PHST- 2010/08/31 06:00 [pubmed] -PHST- 2011/02/18 06:00 [medline] -PHST- 2010/10/01 00:00 [pmc-release] -AID - aps2010123 [pii] -AID - 10.1038/aps.2010.123 [doi] -PST - ppublish -SO - Acta Pharmacol Sin. 2010 Oct;31(10):1267-76. doi: 10.1038/aps.2010.123. Epub 2010 - Aug 30. - -PMID- 19519367 -OWN - NLM -STAT- MEDLINE -DCOM- 20090820 -LR - 20191111 -IS - 2212-4063 (Electronic) -IS - 1871-529X (Linking) -VI - 9 -IP - 2 -DP - 2009 Jun -TI - Experimental animal models of myocardial damage in regenerative medicine studies - involving adult bone marrow derived stem cells: ethical and methodological - implications. -PG - 86-94 -AB - Cardiac performance after myocardial infarction is compromised by ventricular - remodeling, which represents a major cause of late infarct-related chronic heart - failure and death. In recent years, the scientists' interest has focused on the - hypothesis that the administration of bone marrow progenitors, following - myocardial infarction, could ameliorate left ventricular remodeling by continuing - to differentiate along the haematopoietic lineage. This approach has been - developed minding to the consolidated use of transfusions to restore lost or - depleted blood components and, therefore, as an enriched dose of various - progenitors, generally autologous, injected peripherally or directly in the - infarcted area. Since the safety of this therapy was not yet established, for - ethical reasons pioneering researchers involved in these studies used animal - models as surrogate of the human biologic system. Herein this hypothesis of - therapy resulted in an increased use of living animals and in the reappraisal of - models of myocardial damage with limited discussion on the theoretical basis of - animal models applied to cell-based therapies. Recently, the European Union and - its commission for surveillance of laboratory animals advanced a new proposal to - restrict the use of living animals. This review will focus on the history of - models utilization in biomedicine, with particular attention to animal models, - and delineate an operative comparison between the two best known models of - myocardial injury, namely coronary ligation and cryodamage, in the perspective of - adult stem cell research applied to cardiovascular regenerative medicine. -FAU - Ciulla, Michele M -AU - Ciulla MM -AD - Thoracic Surgery, Lung & Cardiovascular Department, Istituto di Medicina - Cardiovascolare, Centro di Fisiologia Clinica e Ipertensione, Laboratory of - Clinical Informatics and Cardiovascular Imaging, University of Milan, Milan, - Italy. michele.ciulla@unimi.it -FAU - Acquistapace, Giulia -AU - Acquistapace G -FAU - Toffetti, Laura -AU - Toffetti L -FAU - Magrini, Fabio -AU - Magrini F -FAU - Paliotti, Roberta -AU - Paliotti R -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Cardiovasc Hematol Disord Drug Targets -JT - Cardiovascular & hematological disorders drug targets -JID - 101269160 -SB - IM -MH - Adult Stem Cells/cytology/*transplantation -MH - Animals -MH - Bone Marrow Cells/cytology -MH - Bone Marrow Transplantation/ethics/methods -MH - Cold Temperature -MH - Disease Models, Animal -MH - Ethics, Medical -MH - Ligation -MH - *Myocardial Infarction/etiology/therapy -MH - Regenerative Medicine/ethics/*methods -MH - Research Design -RF - 74 -EDAT- 2009/06/13 09:00 -MHDA- 2009/08/21 09:00 -CRDT- 2009/06/13 09:00 -PHST- 2009/06/13 09:00 [entrez] -PHST- 2009/06/13 09:00 [pubmed] -PHST- 2009/08/21 09:00 [medline] -AID - 10.2174/187152909788488690 [doi] -PST - ppublish -SO - Cardiovasc Hematol Disord Drug Targets. 2009 Jun;9(2):86-94. doi: - 10.2174/187152909788488690. - -PMID- 17214579 -OWN - NLM -STAT- MEDLINE -DCOM- 20070208 -LR - 20191110 -IS - 1871-5303 (Print) -IS - 1871-5303 (Linking) -VI - 6 -IP - 4 -DP - 2006 Dec -TI - Viral anti-inflammatory reagents: the potential for treatment of arthritic and - vasculitic disorders. -PG - 331-43 -AB - Inflammatory and immune responses are inherent in the development of progressive - arthritic or vasculitic disorders. Arthritis is frequently associated with - accelerated forms of vasculitis; atherosclerosis being one form of accelerated - vasculitis that blocks blood flow causing heart attacks and strokes. The arterial - supply is central to maintaining normal articular function and acts as a conduit - for inflammatory (innate) and immune (antigen dependent) cell trafficking in - joints. The vasculature in some cases can become inflamed in the disease process. - While treatment of severely debilitating arthritic disorders has improved, some - current treatments are limited to reducing symptoms while others act as disease - modifying drugs (DMARDs), but may have limited success. Many current treatments - also have reported adverse side effects. Vasculitic disorders are similarly - debilitating with high associated morbidity and mortality and current therapy for - these disorders is only partially successful. Immune-modifying agents, which - alter vascular inflammation, thus have potential for application in rheumatologic - diseases. Viral immune modulating proteins reduce early arterial inflammatory - responses with associated reductions in atherosclerotic plaque development and - transplant rejection in a wide range of animal models. A clinical trial utilizing - one such viral reagent, a secreted myxomaviral serpin, is currently in progress, - assessing treatment of acute coronary syndrome, a vascular syndrome with marked - up-regulation of systemic inflammatory responses. In this review we examine viral - anti-inflammatory proteins as potential therapeutic reagents for arthritic and - vasculopathic disorders. -FAU - Munuswamy-Ramanujam, G -AU - Munuswamy-Ramanujam G -AD - John P. Robarts' Research Institute, London, ON, Canada. -FAU - Khan, K A -AU - Khan KA -FAU - Lucas, A R -AU - Lucas AR -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Endocr Metab Immune Disord Drug Targets -JT - Endocrine, metabolic & immune disorders drug targets -JID - 101269157 -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Chemokines) -RN - 0 (Interleukin-1) -RN - 0 (Interleukin-18) -RN - 0 (NF-kappa B) -RN - 0 (Serine Proteinase Inhibitors) -RN - 0 (Serpins) -RN - 0 (Viral Proteins) -RN - 130068-27-8 (Interleukin-10) -SB - IM -MH - Animals -MH - Anti-Inflammatory Agents/*pharmacology/therapeutic use -MH - Arthritis/*drug therapy/immunology/physiopathology -MH - Chemokines/antagonists & inhibitors -MH - Humans -MH - Interleukin-1/antagonists & inhibitors -MH - Interleukin-10/antagonists & inhibitors -MH - Interleukin-18/antagonists & inhibitors -MH - NF-kappa B/antagonists & inhibitors -MH - Serine Proteinase Inhibitors/pharmacology/therapeutic use -MH - Serpins/pharmacology/therapeutic use -MH - Vasculitis/*drug therapy/physiopathology -MH - Viral Proteins/*pharmacology/therapeutic use -RF - 135 -EDAT- 2007/01/12 09:00 -MHDA- 2007/02/09 09:00 -CRDT- 2007/01/12 09:00 -PHST- 2007/01/12 09:00 [pubmed] -PHST- 2007/02/09 09:00 [medline] -PHST- 2007/01/12 09:00 [entrez] -AID - 10.2174/187153006779025720 [doi] -PST - ppublish -SO - Endocr Metab Immune Disord Drug Targets. 2006 Dec;6(4):331-43. doi: - 10.2174/187153006779025720. - -PMID- 20965687 -OWN - NLM -STAT- MEDLINE -DCOM- 20110316 -LR - 20101126 -IS - 1769-6623 (Electronic) -IS - 0750-7658 (Linking) -VI - 29 -IP - 11 -DP - 2010 Nov -TI - [Obstructive sleep-apnoea syndrome in adult and its perioperative management]. -PG - 787-92 -LID - 10.1016/j.annfar.2010.08.015 [doi] -AB - Obstructive sleep apnoea (OSA) syndrome in adult is defined as an - Apnoea-Hypopnoea Index (AHI) of 5 or more per hour of sleep in a context of - excessive daytime sleepiness and snoring. OSA is considered as mild with an AHI - of 5-15, moderate with an AHI of 15-30, and severe with an AHI greater than 30. - OSA is a highly prevalent disease since it should affect 7-15% of the middle-aged - population, but most patients are not yet diagnosed for OSA. Middle age, male - gender, obesity and arterial hypertension are main risk factors for OSA in - adults. OSA patients are exposed to higher neurological and cardiovascular - morbidity, including stroke, depression, hypertension, coronary artery disease, - heart failure, arrhythmias. Because OSA may lead to life-threatening problems if - undiagnosed, anaesthesiologists should be aware of their screening role in the - preoperative period. In that way, the STOP-BANG questionnaire is a well-adapted - instrument to screen patients for OSA during the preoperative visit. OSA patients - are exposed to higher preoperative morbidity in relation with OSA severity, - particularly difficult manual ventilation with mask, difficult tracheal - intubation and postoperative upper airway obstruction. The unknown diagnosis of - OSA is one major contributor to facilitate the occurrence of those events. In the - postoperative period, early resuming continuous positive airway pressure and - installing the OSA patient in a nonsupine position could be effective in - preventing pharyngeal obstruction. Considering the timing of postoperative - complications, a careful monitoring in the post-anesthesia care unit for three - hours is an appropriate strategy for a majority of OSA patients. Alternatives to - opioids should be promoted for postoperative pain control. -CI - Copyright © 2010 Elsevier Masson SAS. All rights reserved. -FAU - Payen, J-F -AU - Payen JF -AD - Pôle d'anesthésie-réanimation, hôpital Michallon, CHU de Grenoble, BP 217, 38043 - Grenoble cedex 09, France. jfpayen@ujf-grenoble.fr -FAU - Jaber, S -AU - Jaber S -FAU - Levy, P -AU - Levy P -FAU - Pepin, J-L -AU - Pepin JL -FAU - Fischler, M -AU - Fischler M -LA - fre -PT - English Abstract -PT - Journal Article -PT - Review -TT - Le syndrome d'apnées obstructives du sommeil chez l'adulte: prise en charge - anesthésique. -DEP - 20101020 -PL - France -TA - Ann Fr Anesth Reanim -JT - Annales francaises d'anesthesie et de reanimation -JID - 8213275 -SB - IM -MH - Adult -MH - Aged -MH - Female -MH - Humans -MH - Hypertension/complications/epidemiology -MH - Male -MH - Middle Aged -MH - Obesity/complications/epidemiology -MH - Perioperative Care/*methods -MH - Risk Factors -MH - Sleep Apnea, Obstructive/diagnosis/epidemiology/physiopathology/*therapy -MH - Snoring/complications -EDAT- 2010/10/23 06:00 -MHDA- 2011/03/17 06:00 -CRDT- 2010/10/23 06:00 -PHST- 2010/07/10 00:00 [received] -PHST- 2010/08/30 00:00 [accepted] -PHST- 2010/10/23 06:00 [entrez] -PHST- 2010/10/23 06:00 [pubmed] -PHST- 2011/03/17 06:00 [medline] -AID - S0750-7658(10)00395-3 [pii] -AID - 10.1016/j.annfar.2010.08.015 [doi] -PST - ppublish -SO - Ann Fr Anesth Reanim. 2010 Nov;29(11):787-92. doi: 10.1016/j.annfar.2010.08.015. - Epub 2010 Oct 20. - -PMID- 22172471 -OWN - NLM -STAT- MEDLINE -DCOM- 20120223 -LR - 20171116 -IS - 1532-2165 (Electronic) -IS - 1078-5884 (Linking) -VI - 42 Suppl 2 -DP - 2011 Dec -TI - Chapter III: Management of cardiovascular risk factors and medical therapy. -PG - S33-42 -LID - 10.1016/S1078-5884(11)60011-7 [doi] -AB - Critical limb ischaemia (CLI) is a particularly severe manifestation of lower - limb atherosclerosis posing a major threat to both limb and life of affected - patients. Besides arterial revascularisation, risk-factor modification and - administration of antiplatelet therapy is a major goal in the treatment of CLI - patients. Key elements of cardiovascular risk management are smoking cessation - and treatment of hyperlipidaemia with dietary modification or statins. Moreover, - arterial hypertension and diabetes mellitus should be adequately treated. In CLI - patients not suitable for arterial revascularisation or subsequent to - unsuccessful revascularisation, parenteral prostanoids may be considered. CLI - patients undergoing surgical revascularisation should be treated with beta - blockers. At present, neither gene nor stem-cell therapy can be recommended - outside clinical trials. Of note, walking exercise is contraindicated in CLI - patients due to the risk of worsening pre-existing or causing new ischaemic - wounds. CLI patients are oftentimes medically frail and exhibit significant - comorbidities. Co-existing coronary heart and carotid as well as renal artery - disease should be managed according to current guidelines. Considering the - above-mentioned treatment goals, interdisciplinary treatment approaches for CLI - patients are warranted. Aim of the present manuscript is to discuss currently - existing evidence for both the management of cardiovascular risk factors and - treatment of co-existing disease and to deduct specific treatment - recommendations. -CI - Copyright © 2011 European Society for Vascular and Endovascular Surgery Urology. - Published by Elsevier Ltd. All rights reserved. -FAU - Diehm, N -AU - Diehm N -AD - Clinical and Interventional Angiology, Swiss Cardiovascular Centre, University - Hospital Berne, Switzerland. diehm@gmx.ch -FAU - Schmidli, J -AU - Schmidli J -FAU - Setacci, C -AU - Setacci C -FAU - Ricco, J-B -AU - Ricco JB -FAU - de Donato, G -AU - de Donato G -FAU - Becker, F -AU - Becker F -FAU - Robert-Ebadi, H -AU - Robert-Ebadi H -FAU - Cao, P -AU - Cao P -FAU - Eckstein, H H -AU - Eckstein HH -FAU - De Rango, P -AU - De Rango P -FAU - Teraa, M -AU - Teraa M -FAU - Moll, F L -AU - Moll FL -FAU - Dick, F -AU - Dick F -FAU - Davies, A H -AU - Davies AH -FAU - Lepäntalo, M -AU - Lepäntalo M -FAU - Apelqvist, J -AU - Apelqvist J -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Eur J Vasc Endovasc Surg -JT - European journal of vascular and endovascular surgery : the official journal of - the European Society for Vascular Surgery -JID - 9512728 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Prostaglandins) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Arterial Occlusive Diseases/*prevention & control -MH - Contraindications -MH - Critical Illness -MH - Diabetes Mellitus/prevention & control -MH - Diabetic Foot/*prevention & control -MH - Diet -MH - Exercise Therapy -MH - Genetic Therapy -MH - Humans -MH - Hyperlipidemias/prevention & control -MH - Hypertension/prevention & control -MH - Ischemia/*prevention & control -MH - Lower Extremity/*blood supply -MH - Peripheral Vascular Diseases/*prevention & control -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Prostaglandins/therapeutic use -MH - Risk Assessment -MH - Risk Factors -MH - Smoking Cessation -MH - Stem Cell Transplantation -MH - Vascular Surgical Procedures -EDAT- 2011/12/30 06:00 -MHDA- 2012/02/24 06:00 -CRDT- 2011/12/17 06:00 -PHST- 2011/12/17 06:00 [entrez] -PHST- 2011/12/30 06:00 [pubmed] -PHST- 2012/02/24 06:00 [medline] -AID - S1078-5884(11)60011-7 [pii] -AID - 10.1016/S1078-5884(11)60011-7 [doi] -PST - ppublish -SO - Eur J Vasc Endovasc Surg. 2011 Dec;42 Suppl 2:S33-42. doi: - 10.1016/S1078-5884(11)60011-7. - -PMID- 16670452 -OWN - NLM -STAT- MEDLINE -DCOM- 20060614 -LR - 20121115 -IS - 1557-2501 (Electronic) -IS - 1042-3931 (Linking) -VI - 18 -IP - 5 -DP - 2006 May -TI - Routine pressure-derived fractional flow reserve guidance: from diagnostic to - everyday practice. -PG - 240-5 -AB - The pressure-derived fractional flow reserve (FFR) is a valuable and well - validated index for assessing the ischemic significance of coronary lesions. The - 0.75 cutoff value of FFR discriminates between lesions with and without ischemic - potential, helps decision making as to whether to revascularize a coronary - stenosis and assists in evaluating the results of catheter-based treatment. - Recent data show that the FFR index is also useful in managing patients with - complex coronary disease. The aim of this paper is to provide an overview of the - theoretical background of this index and its clinical applicability in the - catheterization laboratory. -FAU - Hau, William K -AU - Hau WK -AD - Department of Physiology, Institute of Cardiovascular Research and Medicine, Li - Ka Shing Faculty of Medicine, The University of Hong Kong. -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - J Invasive Cardiol -JT - The Journal of invasive cardiology -JID - 8917477 -SB - IM -MH - *Blood Pressure -MH - *Cardiac Catheterization -MH - *Coronary Circulation -MH - Humans -MH - Myocardial Ischemia/*diagnosis/physiopathology/*therapy -RF - 33 -EDAT- 2006/05/04 09:00 -MHDA- 2006/06/15 09:00 -CRDT- 2006/05/04 09:00 -PHST- 2006/05/04 09:00 [pubmed] -PHST- 2006/06/15 09:00 [medline] -PHST- 2006/05/04 09:00 [entrez] -PST - ppublish -SO - J Invasive Cardiol. 2006 May;18(5):240-5. - -PMID- 24180543 -OWN - NLM -STAT- MEDLINE -DCOM- 20140715 -LR - 20131104 -IS - 1744-8298 (Electronic) -IS - 1479-6678 (Linking) -VI - 9 -IP - 6 -DP - 2013 Nov -TI - Stem cells for cardiac repair: problems and possibilities. -PG - 875-84 -LID - 10.2217/fca.13.78 [doi] -AB - Ischemic heart disease is a major cause of death throughout the world. In order - to limit myocardial damage and possibly generate new myocardium, stem cells are - currently being injected into patients with ischemic heart disease. Three major - patient investigations, The LateTIME, the TIME and the Swiss Myocardial - Infarction trials, have recently addressed the questions of whether progenitor - cells from unfractionated bone marrow mononuclear cells limit myocardial damage - and what the optimal time to inject these cells after acute myocardial - infarctions (AMIs) is. In each of these trials, there were no significant - differences between treated and control patients when bone marrow cells were - administered 5-7 days or 2-3 weeks after AMIs. Nevertheless, these investigations - provide important information regarding clinical trial designs. Patients with - AMIs in these trials were treated with percutaneous coronary intervention within - a median of 4-5 h after the onset of chest pain. Thereafter, all patients - received guideline-guided optimal medical therapy. Consequently, the sizes of - AMIs were significantly limited. In patients with small AMIs and near-normal left - ventricular ejection fractions, progenitor cells are least effective. However, - these trials do question whether autologous bone marrow mononuclear cells are the - optimal cells for myocardial repair owing to low numbers of progenitor cells in - bone marrow aspirates and the significant variability in potency and efficacy of - these cells in patients with chronic multisystem diseases. In contrast, the - SCIPIO and the CAUDUCEUS trials examined cardiac progenitor cells in patients - with ischemic cardiomyopathies. These trials reported over 1-2 years that cardiac - progenitor cells produced significant improvements in left ventricular - contractility due to 12-24 g decreases in myocardial scars and 18-23 g increases - in viable myocardial muscle. However, caution must be exercised in the - interpretation of these studies due to the small numbers of highly selected - patients and intra- and inter-observer variability in infarct size measurements. - Anatomical and histological examinations of large numbers of patients treated - with these cells are necessary to confirm significant generation of myocytes and - decreases in infarct size and fibrosis. -FAU - Henning, Robert J -AU - Henning RJ -AD - Center for Cardiovascular Research & the James A Haley VA Hospital, 13000 Bruce B - Downs Boulevard, Tampa, FL, USA. robert.henning@va.gov. -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - England -TA - Future Cardiol -JT - Future cardiology -JID - 101239345 -SB - IM -MH - Humans -MH - *Myocardial Ischemia/pathology/physiopathology/surgery -MH - Myocardium/*pathology -MH - *Recovery of Function -MH - Stem Cell Transplantation/*methods -MH - Transplantation, Autologous -MH - Treatment Outcome -MH - Ventricular Function, Left/*physiology -EDAT- 2013/11/05 06:00 -MHDA- 2014/07/16 06:00 -CRDT- 2013/11/05 06:00 -PHST- 2013/11/05 06:00 [entrez] -PHST- 2013/11/05 06:00 [pubmed] -PHST- 2014/07/16 06:00 [medline] -AID - 10.2217/fca.13.78 [doi] -PST - ppublish -SO - Future Cardiol. 2013 Nov;9(6):875-84. doi: 10.2217/fca.13.78. - -PMID- 17599858 -OWN - NLM -STAT- MEDLINE -DCOM- 20070719 -LR - 20250528 -IS - 1934-2403 (Electronic) -IS - 1530-891X (Linking) -VI - 13 -IP - 3 -DP - 2007 May-Jun -TI - Acute myocardial infarction attributable to adrenergic crises in a patient with - pheochromocytoma and neurofibromatosis 1. -PG - 269-73 -AB - OBJECTIVE: To describe a rare case of acute myocardial infarction in a patient - with neurofibromatosis 1 and pheochromocytoma and to review the literature on the - coexistence of these 2 diseases, the causes of myocardial injury in patients with - pheochromocytoma, and the utility of genetic testing and pheochromocytoma - screening for those patients and their families. METHODS: We present a case - report, including the detailed clinical, laboratory, and radiographic data, - results of adrenal mass pathology, and results of coronary angiography. We also - survey other relevant reports available in the literature. RESULTS: A 43-year-old - woman with a history of long-standing hypertension, neurofibromatosis 1, - headaches, sweating, and palpitations presented to the hospital with chest pain - and shortness of breath. She was found to have an acute myocardial infarction and - pulmonary edema, as well as a right adrenal mass. A pheochromocytoma was - suspected, and phenoxybenzamine was added to her treatment regimen. Cardiac - catheterization showed nonobstructive coronary disease. The levels of plasma - catecholamine metabolites were extremely high. The patient underwent - uncomplicated laparoscopic right adrenalectomy 2 weeks after this admission. - Surgical pathology confirmed the diagnosis of pheochromocytoma. CONCLUSION: - Adrenergic crisis attributable to pheochromocytoma can result in acute myocardial - infarction even in the absence of obstructive coronary disease. Inclusion of - pheochromocytoma in the differential diagnosis of hypertension in patients with - neurofibromatosis is very important and helps avoid mistakes in the management of - such patients. -FAU - Boulkina, Lioubov S -AU - Boulkina LS -AD - Department of Endocrinology, University of North Carolina at Chapel Hill, USA. -FAU - Newton, Christopher A -AU - Newton CA -FAU - Drake, Almond J 3rd -AU - Drake AJ 3rd -FAU - Tanenberg, Robert J -AU - Tanenberg RJ -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -PL - United States -TA - Endocr Pract -JT - Endocrine practice : official journal of the American College of Endocrinology - and the American Association of Clinical Endocrinologists -JID - 9607439 -RN - 0 (Catecholamines) -SB - IM -MH - Adrenal Gland Neoplasms/blood/*complications/surgery -MH - Adrenalectomy -MH - Adult -MH - Catecholamines/adverse effects/blood -MH - Female -MH - Humans -MH - Myocardial Infarction/*etiology -MH - Neurofibromatosis 1/*complications -MH - Pheochromocytoma/blood/*complications/surgery -RF - 19 -EDAT- 2007/06/30 09:00 -MHDA- 2007/07/20 09:00 -CRDT- 2007/06/30 09:00 -PHST- 2007/06/30 09:00 [pubmed] -PHST- 2007/07/20 09:00 [medline] -PHST- 2007/06/30 09:00 [entrez] -AID - S1530-891X(20)41834-8 [pii] -AID - 10.4158/EP.13.3.269 [doi] -PST - ppublish -SO - Endocr Pract. 2007 May-Jun;13(3):269-73. doi: 10.4158/EP.13.3.269. - -PMID- 22733215 -OWN - NLM -STAT- MEDLINE -DCOM- 20130218 -LR - 20250529 -IS - 1759-5010 (Electronic) -IS - 1759-5002 (Linking) -VI - 9 -IP - 10 -DP - 2012 Oct -TI - Inherited calcium channelopathies in the pathophysiology of arrhythmias. -PG - 561-75 -LID - 10.1038/nrcardio.2012.93 [doi] -AB - Regulation of calcium flux in the heart is a key process that affects cardiac - excitability and contractility. Degenerative diseases, such as coronary artery - disease, have long been recognized to alter the physiology of intracellular - calcium regulation, leading to contractile dysfunction or arrhythmias. Since the - discovery of the first gene mutation associated with catecholaminergic - polymorphic ventricular tachycardia (CPVT) in 2001, a new area of interest in - this field has emerged--the genetic abnormalities of key components of the - calcium regulatory system. Such anomalies cause a variety of genetic diseases - characterized by the development of life-threatening arrhythmias in young - individuals. In this Review, we provide an overview of the structural - organization and the function of calcium-handling proteins and describe the - mechanisms by which mutations determine the clinical phenotype. Firstly, we - discuss mutations in the genes encoding the ryanodine receptor 2 (RYR2) and - calsequestrin 2 (CASQ2). These proteins are pivotal to the regulation of calcium - release from the sarcoplasmic reticulum, and mutations can cause CPVT. Secondly, - we review defects in genes encoding proteins that form the voltage-dependent - L-type calcium channel, which regulates calcium entry into myocytes. Mutations in - these genes cause various phenotypes, including Timothy syndrome, Brugada - syndrome, and early repolarization syndrome. The identification of mutations - associated with 'calcium-handling diseases' has led to an improved understanding - of the role of calcium in cardiac physiology. -FAU - Venetucci, Luigi -AU - Venetucci L -AD - Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Via Maugeri 10/10a, - Pavia 27100, Italy. -FAU - Denegri, Marco -AU - Denegri M -FAU - Napolitano, Carlo -AU - Napolitano C -FAU - Priori, Silvia G -AU - Priori SG -LA - eng -GR - FS/10/63/28374/BHF_/British Heart Foundation/United Kingdom -GR - GGP11141/TI_/Telethon/Italy -GR - FS10/63/28,374/BHF_/British Heart Foundation/United Kingdom -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120626 -PL - England -TA - Nat Rev Cardiol -JT - Nature reviews. Cardiology -JID - 101500075 -RN - 0 (CASQ2 protein, human) -RN - 0 (Calcium Channels) -RN - 0 (Calsequestrin) -RN - 0 (Receptors, Adrenergic, beta) -RN - 0 (Ryanodine Receptor Calcium Release Channel) -RN - Short QT Syndrome 1 -RN - Timothy syndrome -SB - IM -MH - Arrhythmias, Cardiac/genetics/*pathology -MH - Autistic Disorder -MH - Brugada Syndrome/genetics/pathology -MH - *Calcium Channels -MH - Calsequestrin/genetics -MH - Channelopathies/genetics/*pathology -MH - Heart Conduction System/abnormalities/pathology -MH - Heart Defects, Congenital/genetics/pathology -MH - Humans -MH - Long QT Syndrome/genetics/pathology -MH - Receptors, Adrenergic, beta/genetics -MH - Risk Assessment -MH - Ryanodine Receptor Calcium Release Channel/genetics -MH - Syndactyly/genetics/pathology -EDAT- 2012/06/27 06:00 -MHDA- 2013/02/19 06:00 -CRDT- 2012/06/27 06:00 -PHST- 2012/06/27 06:00 [entrez] -PHST- 2012/06/27 06:00 [pubmed] -PHST- 2013/02/19 06:00 [medline] -AID - nrcardio.2012.93 [pii] -AID - 10.1038/nrcardio.2012.93 [doi] -PST - ppublish -SO - Nat Rev Cardiol. 2012 Oct;9(10):561-75. doi: 10.1038/nrcardio.2012.93. Epub 2012 - Jun 26. - -PMID- 19839204 -OWN - NLM -STAT- MEDLINE -DCOM- 20091105 -LR - 20250623 -IS - 1865-9217 (Print) -IS - 1865-9217 (Linking) -VI - 103 -IP - 6 -DP - 2009 -TI - [Prognostic value and clinical effectiveness of high sensitivity C-reactive - protein as a marker in primary prevention of major cardiac events]. -PG - 319-29 -AB - OBJECTIVE: To compare the predictive value and the clinical effectiveness of - additional high sensitivity C-reactive protein (hs-CRP) screening as opposed to - traditional risk factor screening alone as a strategy of primary prevention of - coronary artery disease (CAD). METHODS: Following a comprehensive search of 26 - electronic databases by DAHTA DIMDI, a systematic review was performed in - accordance with international standards of evidence based medicine. Eight - publications on risk prediction and one study addressing clinical - decision-analytic modelling were included in the assessment. RESULTS: The - adjusted relative risk of a high hs-CRP level (> 3 mg/L) for myocardial - infarction, cardiac related death, and cardiovascular events ranged from 0.7 to - 2.47 (p < 0.05 in 4 of 7 studies). The area under the receiver operating - characteristic curve (AUC) increased by 0.00 to 0.027 when hs-CRP was added to - the prediction models (4 of 7 studies statistically significant with p < 0.05). - Based on a published decision-analytic model examining hs-CRP screening, the gain - in life expectancy due to statin therapy in individuals with elevated hs-CRP was - similar when compared to patients with hyperlipidaemia. Nonetheless, evidence on - many model parameters was limited. CONCLUSION: Screening with hs-CRP in addition - to traditional risk factors improves risk prediction. However, the incremental - effect is moderate and the clinical relevance remains unclear. -FAU - Schwarzer, Ruth -AU - Schwarzer R -AD - Institut für Public Health, Medical Decision Making and Health Technology - Assessment, Department of Public Health, Information Systems and Health - Technology Assessment, UMIT - University for Health Sciences, Medical Informatics - and Technology, Hall i.T., Osterreich. -FAU - Schnell-Inderst, Petra -AU - Schnell-Inderst P -FAU - Grabein, Kristin -AU - Grabein K -FAU - Göhler, Alexander -AU - Göhler A -FAU - Stollenwerk, Björn -AU - Stollenwerk B -FAU - Grandi, Norma -AU - Grandi N -FAU - Klauss, Volker -AU - Klauss V -FAU - Wasem, Jürgen -AU - Wasem J -FAU - Siebert, Uwe -AU - Siebert U -LA - ger -PT - Journal Article -PT - Systematic Review -TT - Prognostische Wertigkeit und klinische Effektivität des hochsensitiven - C-reaktiven Proteins als Marker in der Primärprävention der koronaren - Herzkrankheit. -PL - Netherlands -TA - Z Evid Fortbild Qual Gesundhwes -JT - Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen -JID - 101477604 -RN - 0 (Biomarkers) -RN - 9007-41-4 (C-Reactive Protein) -SB - IM -MH - Area Under Curve -MH - Biomarkers/blood -MH - C-Reactive Protein/*metabolism -MH - Cardiovascular Diseases/blood/diagnosis/prevention & control -MH - Databases, Factual -MH - Evidence-Based Medicine/standards -MH - Female -MH - Heart Diseases/blood/diagnosis/prevention & control -MH - Humans -MH - Male -MH - Models, Statistical -MH - Myocardial Infarction/blood/*diagnosis/mortality/prevention & control -MH - Predictive Value of Tests -MH - Primary Prevention -RF - 42 -EDAT- 2009/10/21 06:00 -MHDA- 2009/11/06 06:00 -CRDT- 2009/10/21 06:00 -PHST- 2009/10/21 06:00 [entrez] -PHST- 2009/10/21 06:00 [pubmed] -PHST- 2009/11/06 06:00 [medline] -AID - S1865-9217(09)00155-X [pii] -AID - 10.1016/j.zefq.2009.05.020 [doi] -PST - ppublish -SO - Z Evid Fortbild Qual Gesundhwes. 2009;103(6):319-29. doi: - 10.1016/j.zefq.2009.05.020. - -PMID- 21349063 -OWN - NLM -STAT- MEDLINE -DCOM- 20110616 -LR - 20250626 -IS - 1756-5391 (Electronic) -IS - 1756-5391 (Linking) -VI - 3 -IP - 3 -DP - 2010 Aug -TI - Adverse drug reactions of Shenmai injection: a systematic review. -PG - 177-82 -LID - 10.1111/j.1756-5391.2010.01089.x [doi] -AB - OBJECTIVE: To analyze adverse drug reactions (ADRs) associated with Shenmai - injection and possible contributing factors. METHODS: We searched all clinical - studies and ADR reports of Shenmai injection from the China National Knowledge - Infrastructure (CNKI) database, the Data Bank of Chinese Scientific Journals - (VIP), and Chinese Biomedical (CBM) database. We collected relevant information - such as gender, age, allergic history, and diseases treated in ADR cases; types, - occurrence times, and severity of ADRs; and menstruum and compatibility of - Shenmai injection. RESULTS: Of the 1828 clinical studies of Shenmai injection, - 146 (7.99%) mentioned 576 ADR cases; 181 ADR reports mentioned 246 ADR cases. The - most commonly affected age group was 40 to 69 (57.32%). In 36 (14.63%) cases, - patients were described as having an allergic history. The diseases treated in - ADR cases were principally heart failure and coronary artery heart disease. - Thirty-eight (15.45%) of the 246 ADR cases in ADR reports described anaphylactic - shock, while the most common ADR reported in clinical studies was - headache/dizziness. Of the 822 total reported ADR cases, 99 (12.04%) were class - III, and 637 (77.50%) were class IV, and there were no fatalities. The menstruum - of most Shenmai injections was 5% glucose. Incompatible drugs were given in 68 - ADR cases. In ADR cases, the most common dosage of Shenmai injection was 40 to 60 - ml; 215 (80.90%) ADR cases occurred in first time medication, mainly in the first - 30 minutes after injection. CONCLUSIONS: Current evidence shows that Shenmai - injection had lower ADR occurrence, but some potential factors such as irrational - compatibility, dosages may lead to a high risk of ADR. In future, clinicians - should follow indications or functions to promote rational use of Chinese - Medicine Injections . -CI - © 2010 Blackwell Publishing Asia Pty Ltd and Chinese Cochrane Center, West China - Hospital of Sichuan University. -FAU - Zhang, Li -AU - Zhang L -AD - Tianjin University of Traditional Chinese Medicine, China. -FAU - Hu, Jing -AU - Hu J -FAU - Xiao, Lu -AU - Xiao L -FAU - Zhang, Yongling -AU - Zhang Y -FAU - Zhao, Wei -AU - Zhao W -FAU - Zheng, Wenke -AU - Zheng W -FAU - Shang, Hongcai -AU - Shang H -LA - eng -PT - Journal Article -PT - Systematic Review -PL - England -TA - J Evid Based Med -JT - Journal of evidence-based medicine -JID - 101497477 -RN - 0 (Drug Combinations) -RN - 0 (Drugs, Chinese Herbal) -RN - 0 (fructus schizandrae, radix ginseng, radix ophiopogonis drug combination) -SB - IM -MH - Adult -MH - Aged -MH - China -MH - Drug Combinations -MH - Drugs, Chinese Herbal/administration & dosage/*adverse effects -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Panax -MH - Schisandraceae -MH - Severity of Illness Index -EDAT- 2011/02/26 06:00 -MHDA- 2011/06/17 06:00 -CRDT- 2011/02/26 06:00 -PHST- 2011/02/26 06:00 [entrez] -PHST- 2011/02/26 06:00 [pubmed] -PHST- 2011/06/17 06:00 [medline] -AID - 10.1111/j.1756-5391.2010.01089.x [doi] -PST - ppublish -SO - J Evid Based Med. 2010 Aug;3(3):177-82. doi: 10.1111/j.1756-5391.2010.01089.x. - -PMID- 18220658 -OWN - NLM -STAT- MEDLINE -DCOM- 20080311 -LR - 20191210 -IS - 1573-3998 (Print) -IS - 1573-3998 (Linking) -VI - 3 -IP - 1 -DP - 2007 Feb -TI - Cardiac and metabolic consequences of aerobic exercise training in experimental - diabetes. -PG - 75-84 -AB - The experimental literature of the foregoing decade has furnished an assemblage - of mechanisms explaining the metabolic perturbations and overall decline in - cardiac performance implicated in the pathogenesis of diabetes mellitus. - Particularly, the experimentally-induced diabetic rat model has been - indispensable in the examination of diabetic cardiomyopathy, an entity distinctly - separable from atherosclerosis, hypertension, coronary artery disease and - valvular dysfunction, yet convincingly attributable to the increase in - cardiac-associated mortality commonly observed in the diabetic patient. The - widespread epidemic of diabetes mellitus in developed societies has elicited - considerable attention and the role of exercise as an adjuvant therapy in - diabetes management has been increasingly emphasized. However, the evidence - endorsing the beneficial attributes of exercise in the diabetic state is - indeterminate despite markedly observed increases in myocardial and skeletal - muscle glucose homeostasis, endothelial and autonomic function, insulin - sensitivity and amelioration of diabetes pathogenesis. As evidenced by review of - the experimental literature, a mild to moderately intense exercise regime may be - a reliably implicated insulin-sensitizing therapy for the experimentally-diabetic - rat model as well as the human diabetic patient. Notably, the cardio-protective - and metabolic benefits of aerobic exercise are seemingly more pronounced in those - individuals most susceptible to diabetes progression. -FAU - Saraceni, Christine -AU - Saraceni C -AD - Midwestern University, Department of Physiology, 19555 North 59th Avenue, - Glendale, AZ 85308, USA. -FAU - Broderick, Tom L -AU - Broderick TL -LA - eng -PT - Evaluation Study -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Diabetes Rev -JT - Current diabetes reviews -JID - 101253260 -RN - 0 (Contractile Proteins) -RN - 0 (Ketones) -RN - 0 (Mitochondrial Proteins) -RN - 5W494URQ81 (Streptozocin) -RN - IY9XDZ35W2 (Glucose) -SB - IM -MH - Animals -MH - Autonomic Nervous System/physiopathology -MH - Biological Transport/physiology -MH - Contractile Proteins/metabolism -MH - Diabetes Mellitus, - Experimental/complications/*metabolism/*physiopathology/prevention & control -MH - Glucose/metabolism -MH - Heart/*physiopathology -MH - Homeostasis/physiology -MH - Ischemia/complications/physiopathology -MH - Ketones/metabolism -MH - Lipid Metabolism/physiology -MH - Mitochondrial Proteins/metabolism -MH - Models, Biological -MH - Myocardium/metabolism -MH - Oxidative Stress/physiology -MH - Physical Conditioning, Animal/*physiology -MH - Rats -MH - Streptozocin -MH - Sympathetic Nervous System/physiopathology -RF - 67 -EDAT- 2008/01/29 09:00 -MHDA- 2008/03/12 09:00 -CRDT- 2008/01/29 09:00 -PHST- 2008/01/29 09:00 [pubmed] -PHST- 2008/03/12 09:00 [medline] -PHST- 2008/01/29 09:00 [entrez] -AID - 10.2174/157339907779802111 [doi] -PST - ppublish -SO - Curr Diabetes Rev. 2007 Feb;3(1):75-84. doi: 10.2174/157339907779802111. - -PMID- 16293956 -OWN - NLM -STAT- MEDLINE -DCOM- 20060615 -LR - 20091111 -IS - 0025-7931 (Print) -IS - 0025-7931 (Linking) -VI - 73 -IP - 1 -DP - 2006 -TI - Deleterious effects of sleep-disordered breathing on the heart and vascular - system. -PG - 124-30 -AB - Obstructive sleep apnea (OSA) is the most common form of sleep-disordered - breathing, affecting 5-15% of the population. It is characterized by intermittent - episodes of partial or complete obstruction of the upper airway during sleep that - disrupts normal ventilation and sleep architecture, and is typically associated - with excessive daytime sleepiness, snoring, and witnessed apneas. Patients with - obstructive sleep apnea present risk to the general public safety by causing - 8-fold increase in vehicle accidents, and they may themselves also suffer from - the physiologic consequences of OSA; these include hypertension, coronary artery - disease, stroke, congestive heart failure, pulmonary hypertension, and cardiac - arrhythmias. Of these possible cardiovascular consequences, the association - between OSA and hypertension has been found to be the most convincing. Although - the exact mechanism has not been understood, there is some evidence that OSA is - associated with frequent apneas causing mechanical effects on intrathoracic - pressure, cardiac function, and intermittent hypoxemia, which may in turn cause - endothelial dysfunction and increase in sympathetic drive. Therapy with - continuous positive airway pressure has been demonstrated to improve - cardiopulmonary hemodynamics in patients with OSA and may reverse the endothelial - cell dysfunction. Despite the availability of diagnostic measures and effective - treatment, many patients with sleep-disordered breathing remain undiagnosed. - Therefore, OSA continues to be a significant health risk both for affected - individuals and for the general public. Awareness and timely initiation of an - effective treatment may prevent potential deleterious cardiovascular effects of - OSA. -CI - Copyright 2006 S. Karger AG, Basel. -FAU - Dincer, H Erhan -AU - Dincer HE -AD - Pulmonary, Critical Care and Sleep Medicine, VA Southern Nevada Health Care - System, Las Vegas, NV 89036, USA. Huseyin.Dincer@med.va.gov -FAU - O'Neill, William -AU - O'Neill W -LA - eng -PT - Journal Article -PT - Review -DEP - 20051115 -PL - Switzerland -TA - Respiration -JT - Respiration; international review of thoracic diseases -JID - 0137356 -SB - IM -MH - Arrhythmias, Cardiac/epidemiology/physiopathology -MH - Atherosclerosis/epidemiology/physiopathology -MH - Cardiovascular Diseases/*epidemiology/*physiopathology -MH - Endothelium, Vascular/physiopathology -MH - Hemodynamics -MH - Humans -MH - Hypertension, Pulmonary/epidemiology/physiopathology -MH - Myocardial Infarction/epidemiology/physiopathology -MH - Risk Factors -MH - Sleep Apnea, Obstructive/*complications/*epidemiology/*physiopathology -MH - Stroke/epidemiology -MH - Syndrome -MH - Ventricular Dysfunction/physiopathology -RF - 88 -EDAT- 2005/11/19 09:00 -MHDA- 2006/06/16 09:00 -CRDT- 2005/11/19 09:00 -PHST- 2005/04/25 00:00 [received] -PHST- 2005/08/23 00:00 [accepted] -PHST- 2005/11/19 09:00 [pubmed] -PHST- 2006/06/16 09:00 [medline] -PHST- 2005/11/19 09:00 [entrez] -AID - 89814 [pii] -AID - 10.1159/000089814 [doi] -PST - ppublish -SO - Respiration. 2006;73(1):124-30. doi: 10.1159/000089814. Epub 2005 Nov 15. - -PMID- 16959725 -OWN - NLM -STAT- MEDLINE -DCOM- 20061215 -LR - 20131121 -IS - 1538-5744 (Print) -IS - 1538-5744 (Linking) -VI - 40 -IP - 4 -DP - 2006 Aug-Sep -TI - Optimal medical management of peripheral arterial disease. -PG - 312-27 -AB - Patients with peripheral vascular disease are less likely to receive optimal - medical management than patients with coronary artery disease. However, early - medical treatment is critical because it is profoundly beneficial and the - benefits are maximized. Even in patients with advanced disease requiring invasive - intervention, medical management has been proven to improve outcome, prolong the - success of the intervention, improve functional capacity, and prolong life. The - vascular surgeon should be knowledgeable enough to initiate basic medical therapy - and to define for their patients the goals that need to be met to optimize their - medical management. The vascular surgeon should be instrumental in assuring that - the peripheral vascular patient receives medical therapy of the same standard as - the patient with coronary disease. The major modifiable risk factors in the - vascular patient are: smoking, high blood pressure, hyperlipidemia, physical - inactivity, obesity, and diabetes. In addition, the use of beta blockers for - patients with coronary disease and antiplatelet therapy as well as - angiotensin-converting enzyme (ACE) inhibitors are recommended for all patients - with peripheral vascular disease. Statins have favorable effects on multiple - interrelated aspects of vascular biology important in atherosclerosis. In - particular they have beneficial effects on inflammation, plaque stabilization, - endothelial dysfunction, and thrombosis. Statins have also been shown to be - beneficial in acute vascular events. Angiotensin-converting enzyme inhibitors - have been shown to reduce cardiovascular morbidity and mortality in patients with - peripheral arterial disease regardless of the presence or absence of - hypertension. A number of the pleiotropic effects of statins are shared by ACE - inhibitors. In summary, patients with known vascular disease should be treated - aggressively with a combination of a HMG CoA reductase inhibitor, an - angiotensin-converting enzyme inhibitor, an antiplatelet agent and a beta blocker - if there is a history of coronary disease. They should also receive tight control - of their blood pressure and blood sugar. Smokers should be encouraged to stop - smoking and should be provided with pharmaceutical and emotional support by their - physicians. All of these patients should have their body mass index as close to - normal as possible and be on a therapeutic lifestyle diet. Regular aerobic - exercise is also indicated. Patients with symptomatic claudication should be - considered for cilostazol. Patients with multiple risk factors for vascular - disease, but who do not have documented disease should also be on statin therapy. - As more studies define the linear relationship between lower LDL-C levels and - lowered risk of vascular events, indicating that the lower the LDL-C level, the - lower the risk, experts are advocating more aggressive lipid-lowering therapy. In - patients with peripheral arterial disease, some experts now advocate lowering the - goal of LDL therapy to 70 mg/dL. -FAU - Rice, Terry W -AU - Rice TW -AD - Division of Vascular Surgery and Endovascular Therapy, Houston, TX 77030, USA. -FAU - Lumsden, Alan B -AU - Lumsden AB -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Vasc Endovascular Surg -JT - Vascular and endovascular surgery -JID - 101136421 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Anticoagulants) -RN - 0 (Cholesterol, LDL) -RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) -RN - 0 (Lipoprotein(a)) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0LVT1QZ0BA (Homocysteine) -SB - IM -CIN - Vasc Endovascular Surg. 2007 Feb-Mar;41(1):87. doi: 10.1177/1538574406297268. - PMID: 17277251 -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angiotensin-Converting Enzyme Inhibitors/*therapeutic use -MH - Anticoagulants/therapeutic use -MH - Cholesterol, LDL/blood -MH - Clinical Trials as Topic -MH - Diabetes Complications/blood/drug therapy/etiology -MH - Drug Therapy, Combination -MH - Exercise Therapy -MH - Homocysteine/blood -MH - Humans -MH - Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use -MH - Hyperlipidemias/complications/drug therapy -MH - Hypertension/complications/drug therapy -MH - Intermittent Claudication/blood/drug therapy/etiology -MH - Lipoprotein(a)/blood -MH - Obesity/complications/drug therapy -MH - Peripheral Vascular Diseases/blood/*drug therapy/*etiology -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Practice Guidelines as Topic -MH - Risk Factors -MH - Smoking/adverse effects -RF - 71 -EDAT- 2006/09/09 09:00 -MHDA- 2006/12/16 09:00 -CRDT- 2006/09/09 09:00 -PHST- 2006/09/09 09:00 [pubmed] -PHST- 2006/12/16 09:00 [medline] -PHST- 2006/09/09 09:00 [entrez] -AID - 40/4/312 [pii] -AID - 10.1177/1538574406291835 [doi] -PST - ppublish -SO - Vasc Endovascular Surg. 2006 Aug-Sep;40(4):312-27. doi: 10.1177/1538574406291835. - -PMID- 17345122 -OWN - NLM -STAT- MEDLINE -DCOM- 20070927 -LR - 20220316 -IS - 0364-2313 (Print) -IS - 0364-2313 (Linking) -VI - 31 -IP - 4 -DP - 2007 Apr -TI - Peripheral arterial occlusive disease: magnetic resonance imaging and the role of - aggressive medical management. -PG - 695-704 -AB - Atherosclerosis accounts for most peripheral arterial occlusive disease (PAD). - Although many of the risk factors for atherosclerotic coronary artery disease - (CAD) such as hyperlipidemia have been identified as risk factors for peripheral - arterial disease, strong evidence is lacking that risk factor modification is - effective in halting progression or improving outcomes. A better understanding is - needed regarding the clinical and pathophysiologic responses to risk factor - modification. This review describes current advances in the medical management - for PAD including lipid modification antiplatelet therapy, angiotensin-converting - enzyme (ACE) inhibitors, beta-blockers, exercise, and endovascular intervention. - In addition, we discuss our active ELIMIT Trial (Effect of Lipid Modification on - Peripheral Arterial Disease after Endovascular Intervention). We test the - hypothesis that an aggressive regimen of serum lipid modification will inhibit - the progression of atherosclerosis in femoral arteries and reduce the incidence - of restenosis of femoral arteries following endovascular stenting by decreasing - thrombosis and inflammation. This study will provide a novel strategy for - retarding or preventing progression of atherosclerosis and re-stenosis of - peripheral arterial disease following arterial revascularization procedures. - Importantly, our magnetic resonance imaging studies will provide quantitative - data on the vascular lesions in PAD. These studies will advance our understanding - of the molecular mechanisms of inflammation and thrombosis associated with - aggressive lipid modification. -FAU - Lumsden, Alan B -AU - Lumsden AB -AD - Methodist DeBakey Heart Center, Baylor College of Medicine, 1709 Dryden Street, - Suite 1500, Houston, Texas 77030, USA. alumsden@bcm.tmc.edu -FAU - Rice, Terry W -AU - Rice TW -FAU - Chen, Changyi -AU - Chen C -FAU - Zhou, Wei -AU - Zhou W -FAU - Lin, Peter H -AU - Lin PH -FAU - Bray, Paul -AU - Bray P -FAU - Morrisett, Joel -AU - Morrisett J -FAU - Nambi, Vijay -AU - Nambi V -FAU - Ballantyne, Christie -AU - Ballantyne C -LA - eng -GR - R01 HL75824/HL/NHLBI NIH HHS/United States -PT - Journal Article -PT - Research Support, N.I.H., Extramural -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United States -TA - World J Surg -JT - World journal of surgery -JID - 7704052 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Angiotensin-Converting Enzyme Inhibitors) -RN - 0 (Platelet Aggregation Inhibitors) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Algorithms -MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use -MH - Arterial Occlusive Diseases/*diagnosis/*therapy -MH - Atherosclerosis/*diagnosis/*therapy -MH - Clinical Trials as Topic -MH - Disease Progression -MH - Exercise Therapy -MH - Femoral Artery/pathology -MH - Humans -MH - Magnetic Resonance Imaging/*methods -MH - Peripheral Vascular Diseases/*diagnosis/*therapy -MH - Platelet Aggregation Inhibitors/therapeutic use -MH - Risk Factors -RF - 54 -EDAT- 2007/03/09 09:00 -MHDA- 2007/09/28 09:00 -CRDT- 2007/03/09 09:00 -PHST- 2007/03/09 09:00 [pubmed] -PHST- 2007/09/28 09:00 [medline] -PHST- 2007/03/09 09:00 [entrez] -AID - 10.1007/s00268-006-0732-y [doi] -PST - ppublish -SO - World J Surg. 2007 Apr;31(4):695-704. doi: 10.1007/s00268-006-0732-y. - -PMID- 21905496 -OWN - NLM -STAT- MEDLINE -DCOM- 20111011 -LR - 20220419 -IS - 1018-9068 (Print) -IS - 1018-9068 (Linking) -VI - 21 -IP - 5 -DP - 2011 -TI - Consensus statement on the diagnosis, management, and treatment of angioedema - mediated by bradykinin. Part I. Classification, epidemiology, pathophysiology, - genetics, clinical symptoms, and diagnosis. -PG - 333-47; quiz follow 347 -AB - BACKGROUND: There are no Spanish guidelines or consensus statement on - bradykinin-induced angioedema. AIM: To review the pathophysiology, genetics, and - clinical symptoms of the different types of bradykinin-induced angioedema and to - draft a consensus statement in light of currently available scientific evidence - and the experience of experts. This statement will serve as a guideline to health - professionals. METHODS: The consensus was led by the Spanish Study Group on - Bradykinin-Induced Angioedema (SGBA), a working group of the Spanish Society of - Allergology and Clinical Immunology. A review was conducted of scientific papers - on different types of bradykinin-induced angioedema (hereditary and acquired - angioedema due to C1 inhibitor deficiency, hereditary angioedema related to - estrogens, angioedema induced by angiotensin-converting enzyme inhibitors). - Several discussion meetings of the SGBA were held in Madrid to reach the - consensus. RESULTS: The pathophysiology, genetics, and clinical symptoms of the - different types of angioedema are reviewed. Diagnostic approaches are discussed - and the consensus reached is described. CONCLUSIONS: A review of - bradykinin-induced angioedema and a consensus on diagnosis are presented. -FAU - Caballero, T -AU - Caballero T -AD - Servicio de Alergia, Hospital La Paz Health Research Institute (IdiPaz), Madrid, - Spain. tcaballero.hulp@salud.madrid.org -FAU - Baeza, M L -AU - Baeza ML -FAU - Cabañas, R -AU - Cabañas R -FAU - Campos, A -AU - Campos A -FAU - Cimbollek, S -AU - Cimbollek S -FAU - Gómez-Traseira, C -AU - Gómez-Traseira C -FAU - González-Quevedo, T -AU - González-Quevedo T -FAU - Guilarte, M -AU - Guilarte M -FAU - Jurado-Palomo, G J -AU - Jurado-Palomo GJ -FAU - Larco, J I -AU - Larco JI -FAU - López-Serrano, M C -AU - López-Serrano MC -FAU - López-Trascasa, M -AU - López-Trascasa M -FAU - Marcos, C -AU - Marcos C -FAU - Muñoz-Caro, J M -AU - Muñoz-Caro JM -FAU - Pedrosa, M -AU - Pedrosa M -FAU - Prior, N -AU - Prior N -FAU - Rubio, M -AU - Rubio M -FAU - Sala-Cunill, A -AU - Sala-Cunill A -CN - Spanish Study Group on Bradykinin-Induced Angioedema -CN - Grupo Español de Estudio del Angioedema mediado por Bradicinina -LA - eng -PT - Consensus Development Conference -PT - Journal Article -PT - Multicenter Study -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - Spain -TA - J Investig Allergol Clin Immunol -JT - Journal of investigational allergology & clinical immunology -JID - 9107858 -RN - 0 (Vasodilator Agents) -RN - S8TIM42R2W (Bradykinin) -SB - IM -EIN - J Investig Allergol Clin Immunol. 2012;22(2):3 p following 153 -MH - *Angioedema/classification -MH - Bradykinin/*adverse effects/therapeutic use -MH - Coronary Vasospasm/*drug therapy -MH - Drug Hypersensitivity/diagnosis/epidemiology/genetics/*physiopathology -MH - Emergency Medical Services -MH - Evidence-Based Medicine -MH - Expert Testimony -MH - Humans -MH - Practice Guidelines as Topic -MH - Risk Factors -MH - Spain -MH - Vasodilator Agents/*adverse effects/therapeutic use -EDAT- 2011/09/13 06:00 -MHDA- 2011/10/12 06:00 -CRDT- 2011/09/13 06:00 -PHST- 2011/09/13 06:00 [entrez] -PHST- 2011/09/13 06:00 [pubmed] -PHST- 2011/10/12 06:00 [medline] -PST - ppublish -SO - J Investig Allergol Clin Immunol. 2011;21(5):333-47; quiz follow 347. - -PMID- 18004254 -OWN - NLM -STAT- MEDLINE -DCOM- 20071217 -LR - 20131121 -IS - 1027-6661 (Print) -IS - 1027-6661 (Linking) -VI - 13 -IP - 2 -DP - 2007 -TI - [Therapy with aspirin: a new look at the old problem]. -PG - 9-14 -AB - Aspirin is known to be efficient in secondary prevention of atherothrombosis. - However, a considerable number of patients despite daily doses of aspirin still - experience and suffer from various cardiovascular complications. In the medical - literature this phenomenon was described as <>, however, no - well-defined criteria for this notion have been developed as yet. The - overwhelming majority of researchers take the term <> to mean - both inability of the drug to prevent development of secondary thrombotic events, - and its failure to adequately inhibit the function of blood platelets according - to the findings of various laboratory tests. The incidence of detecting <> varies considerably depending on the pathology involved and the - method(s) used, amounting to from 5 to 70% of the cases. Amongst possible - mechanisms capable of influencing the aspirin's clinical effect considered - (herein, are the following aspects: polymorphism and/or mutation of the - cyclooxigenese-1gene, production of thromboxane A2 in macrophages and endothelial - cells via cyclooxigenese-2 polymorphism of Ilb/IIIa platelet receptors, - competitive interaction with non-steroidal anti-inflammatory drugs for binding - with the cyclooxigenese-1 of blood platelets, and platelet activation via other - pathways which are not blocked by aspirin. -FAU - Katkova, O V -AU - Katkova OV -FAU - Laguta, P S -AU - Laguta PS -FAU - Panchenko, E P -AU - Panchenko EP -LA - rus -PT - English Abstract -PT - Journal Article -PT - Review -PL - Russia (Federation) -TA - Angiol Sosud Khir -JT - Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery -JID - 9604504 -RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) -RN - 0 (Fibrinolytic Agents) -RN - EC 1.14.99.1 (Cyclooxygenase 2) -RN - R16CO5Y76E (Aspirin) -SB - IM -MH - Anti-Inflammatory Agents, Non-Steroidal/*pharmacology/*therapeutic use -MH - Aspirin/*pharmacology/*therapeutic use -MH - Biological Availability -MH - Coronary Thrombosis/prevention & control -MH - Cyclooxygenase 2/genetics -MH - Drug Resistance -MH - Fibrinolytic Agents/pharmacology/therapeutic use -MH - Humans -MH - Intracranial Thrombosis/prevention & control -MH - Point Mutation/genetics -MH - Polymorphism, Genetic/genetics -RF - 38 -EDAT- 2007/11/16 09:00 -MHDA- 2007/12/18 09:00 -CRDT- 2007/11/16 09:00 -PHST- 2007/11/16 09:00 [pubmed] -PHST- 2007/12/18 09:00 [medline] -PHST- 2007/11/16 09:00 [entrez] -PST - ppublish -SO - Angiol Sosud Khir. 2007;13(2):9-14. - -PMID- 16814883 -OWN - NLM -STAT- MEDLINE -DCOM- 20070409 -LR - 20101118 -IS - 1874-1754 (Electronic) -IS - 0167-5273 (Linking) -VI - 116 -IP - 1 -DP - 2007 Mar 2 -TI - Percutaneous revascularization of chronic total occlusions: review of the role of - invasive and non-invasive imaging modalities. -PG - 1-6 -AB - Percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) has a - lower success rate than PCI of non-occluded coronary stenosis. Failure to cross - the occlusive lesion with a guide wire is the main cause of unsuccessful PCI of a - CTO. Multi-imaging modalities may provide valuable information for PCI of CTO. - This paper reviews the role of invasive and non-invasive imaging modalities such - as intravascular ultrasound, optical coherent reflectometry, CT coronary - angiography and cardiac magnetic resonance imaging in facilitating percutaneous - coronary intervention of CTO. -FAU - Soon, Kean H -AU - Soon KH -AD - Western Hospital, Footscray, Melbourne, Victoria, Australia. kean.soon@wh.org.au -FAU - Selvanayagam, Joseph B -AU - Selvanayagam JB -FAU - Cox, Nicholas -AU - Cox N -FAU - Kelly, Anne-Maree -AU - Kelly AM -FAU - Bell, Kevin W -AU - Bell KW -FAU - Lim, Yean L -AU - Lim YL -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20060630 -PL - Netherlands -TA - Int J Cardiol -JT - International journal of cardiology -JID - 8200291 -SB - IM -MH - Angioplasty, Balloon, Coronary/*instrumentation/*methods -MH - Animals -MH - Catheter Ablation/instrumentation -MH - Coronary Angiography/instrumentation/methods -MH - Coronary Stenosis/*diagnosis -MH - Equipment Design -MH - Humans -MH - Magnetic Resonance Imaging/instrumentation/methods -MH - Predictive Value of Tests -MH - Tomography, Optical Coherence/instrumentation/methods -MH - Ultrasonography, Interventional/instrumentation/methods -RF - 29 -EDAT- 2006/07/04 09:00 -MHDA- 2007/04/10 09:00 -CRDT- 2006/07/04 09:00 -PHST- 2005/10/24 00:00 [received] -PHST- 2006/02/25 00:00 [revised] -PHST- 2006/03/25 00:00 [accepted] -PHST- 2006/07/04 09:00 [pubmed] -PHST- 2007/04/10 09:00 [medline] -PHST- 2006/07/04 09:00 [entrez] -AID - S0167-5273(06)00413-X [pii] -AID - 10.1016/j.ijcard.2006.03.023 [doi] -PST - ppublish -SO - Int J Cardiol. 2007 Mar 2;116(1):1-6. doi: 10.1016/j.ijcard.2006.03.023. Epub - 2006 Jun 30. - -PMID- 21434492 -OWN - NLM -STAT- MEDLINE -DCOM- 20110407 -LR - 20181201 -IS - 1128-3602 (Print) -IS - 1128-3602 (Linking) -VI - 15 -IP - 2 -DP - 2011 Feb -TI - Role of biomarkers in patients with dyspnea. -PG - 229-40 -AB - BACKGROUND: The use of biomarkers has been demonstrated useful in many acute - diseases both for diagnosis, prognosis and risk stratification. OBJECTIVES: The - purpose of this review is to analyze several biomarkers of potential use in - patients referring to Emergency Department with acute dyspnea. STATE OF THE ART: - The role of natriuretic peptides has a proven utility in the diagnosis, risk - stratification, patient management and prediction of outcome in acute and chronic - heart failure (HF). New immunoassays are available for the detection of - mid-region prohormones in patients with acute dyspnea such as Mid-region - pro-adrenomedullin (MR-proADM) and Mid-region pro-atrial natriuretic peptide - (MR-proANP). Also procalcitonin, copeptin and D-dimer, which are markers of - inflammation, bacterial infections and sepsis, seem to be useful in the - differential diagnosis of dyspnea. Conventional and high-sensitivity troponins - are fundamental, not only in the diagnosis of acute coronary syndromes, but also - as indicators of mortality in patients with acute decompensated heart failure. - PERSPECTIVES: Further studies with randomized controlled clinical trials will be - needed to prove the theoretical clinical advantages offered by a shortness of - breath biomarkers in terms of diagnostic, prognostic, cost effective work-up and - management of patients with acute dyspnea. CONCLUSIONS: A multimarker pannel - approach performed by rapid and accurate assays could be useful for emergency - physicians to promptly identify different causes of dyspnea thus managing to - improve diagnosis, treatment and risk stratification. -FAU - Gori, C S -AU - Gori CS -AD - Emergency Department, 2nd Medical School, Sapienza University of Rome, - Sant'Andrea Hospital, Rome, Italy. -FAU - Magrini, L -AU - Magrini L -FAU - Travaglino, F -AU - Travaglino F -FAU - Di Somma, S -AU - Di Somma S -LA - eng -PT - Journal Article -PT - Review -PL - Italy -TA - Eur Rev Med Pharmacol Sci -JT - European review for medical and pharmacological sciences -JID - 9717360 -RN - 0 (Biomarkers) -RN - 0 (CALCA protein, human) -RN - 0 (Fibrin Fibrinogen Degradation Products) -RN - 0 (Peptide Fragments) -RN - 0 (Protein Precursors) -RN - 0 (Troponin T) -RN - 0 (fibrin fragment D) -RN - 0 (midregional pro-atrial natriuretic peptide, human) -RN - 0 (pro-brain natriuretic peptide (1-76)) -RN - 114471-18-0 (Natriuretic Peptide, Brain) -RN - 148498-78-6 (Adrenomedullin) -RN - 85637-73-6 (Atrial Natriuretic Factor) -RN - 9007-12-9 (Calcitonin) -RN - JHB2QIZ69Z (Calcitonin Gene-Related Peptide) -SB - IM -MH - Acute Disease -MH - Adrenomedullin/blood -MH - Atrial Natriuretic Factor/blood -MH - Biomarkers/*blood -MH - Calcitonin/blood -MH - Calcitonin Gene-Related Peptide -MH - Dyspnea/blood/*diagnosis -MH - Fibrin Fibrinogen Degradation Products/analysis -MH - Humans -MH - Natriuretic Peptide, Brain/blood -MH - Peptide Fragments/blood -MH - Protein Precursors/blood -MH - Troponin T/blood -EDAT- 2011/03/26 06:00 -MHDA- 2011/04/08 06:00 -CRDT- 2011/03/26 06:00 -PHST- 2011/03/26 06:00 [entrez] -PHST- 2011/03/26 06:00 [pubmed] -PHST- 2011/04/08 06:00 [medline] -PST - ppublish -SO - Eur Rev Med Pharmacol Sci. 2011 Feb;15(2):229-40. - -PMID- 19601787 -OWN - NLM -STAT- MEDLINE -DCOM- 20091106 -LR - 20220409 -IS - 1875-533X (Electronic) -IS - 0929-8673 (Linking) -VI - 16 -IP - 19 -DP - 2009 -TI - Recent advances on the roles of NO in cancer and chronic inflammatory disorders. -PG - 2373-94 -AB - Nitric oxide (NO) is a short-life molecule produced by the enzyme known as the - nitric oxide synthase (NOS), in a reaction that converts arginine and oxygen into - citrulline and NO. There are three isoforms of the enzyme: neuronal NOS (nNOS, - also called NOS1), inducible NOS (iNOS or NOS2), and endothelial NOS (eNOS or - NOS3). It is now known that each of these isoforms may be expressed in a variety - of tissues and cell types. This paper is a review of the current knowledge of - various functions of NO in diseases. We discuss in more detail its role in - Cancer, the role of NO in myocardial pathophysiology, in central nervous system - (CNS) pathologies. Other diseases such as inflammation, asthma, in chronic liver - diseases, inflammatory bowel disease (IBD), arthritis, are also discussed. This - review also covers the role of NO in cardiovascular, central nervous, pancreas, - lung, gut, kidney, myoskeletal and chronic liver diseases (CLD). The ubiquitous - role that the simple gas nitric oxide plays in the body, from maintaining - vascular homeostasis and fighting infections to acting as a neurotransmitter and - its role in cancer, has spurred a lot of interest among researchers all over the - world. Nitric oxide plays an important role in the physiologic modulation of - coronary artery tone and myocardial function. Nitric oxide from iNOS appears to - be a key mediator of such glial-induced neuronal death. The high sensitivity of - neurons to NO is partly due to NO causing inhibition of respiration, rapid - glutamate release from both astrocytes and neurons, and subsequent excitotoxic - death of the neurons. -FAU - Kanwar, Jagat R -AU - Kanwar JR -AD - Laboratory of Immunology and Molecular Biomedical Research, Centre for - Biotechnology and Interdisciplinary Biosciences (BioDeakin), Institute for - Technology & Research Innovation, Geelong Technology Precinct (GTP), Deakin - University, Pigdons Road, Waurn Ponds, Geelong, Victoria 3217, Australia. - jagat.kanwar@deakin.edu.au -FAU - Kanwar, Rupinder K -AU - Kanwar RK -FAU - Burrow, Hannah -AU - Burrow H -FAU - Baratchi, Sara -AU - Baratchi S -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -PL - United Arab Emirates -TA - Curr Med Chem -JT - Current medicinal chemistry -JID - 9440157 -RN - 0 (Enzyme Inhibitors) -RN - 31C4KY9ESH (Nitric Oxide) -RN - EC 1.14.13.39 (Nitric Oxide Synthase) -SB - IM -MH - Arthritis/etiology -MH - Diabetes Mellitus/etiology -MH - Enzyme Inhibitors/pharmacology -MH - Heart Diseases/etiology -MH - Humans -MH - Inflammation/*etiology -MH - Liver Diseases/etiology -MH - Lung Diseases/etiology -MH - Neoplasms/*etiology -MH - Neurodegenerative Diseases/etiology -MH - Nitric Oxide/*physiology -MH - Nitric Oxide Synthase/metabolism -MH - Stroke/etiology -RF - 249 -EDAT- 2009/07/16 09:00 -MHDA- 2009/11/07 06:00 -CRDT- 2009/07/16 09:00 -PHST- 2009/07/16 09:00 [entrez] -PHST- 2009/07/16 09:00 [pubmed] -PHST- 2009/11/07 06:00 [medline] -AID - 10.2174/092986709788682155 [doi] -PST - ppublish -SO - Curr Med Chem. 2009;16(19):2373-94. doi: 10.2174/092986709788682155. - -PMID- 18688681 -OWN - NLM -STAT- MEDLINE -DCOM- 20090326 -LR - 20211020 -IS - 1525-1497 (Electronic) -IS - 0884-8734 (Print) -IS - 0884-8734 (Linking) -VI - 23 -IP - 11 -DP - 2008 Nov -TI - Takotsubo cardiomyopathy. -PG - 1904-8 -LID - 10.1007/s11606-008-0744-4 [doi] -AB - BACKGROUND: Takotsubo cardiomyopathy is a novel, yet well-described, reversible - cardiomyopathy triggered by profound psychological or physical stress with a - female predominance. OBJECTIVE: This review is designed to increase general - clinician awareness about the diagnosis, incidence, pathogenesis, and therapies - of this entity. DATA SOURCES: A complete search of multiple electronic databases - (Pubmed, EMBASE, Science Citation Index) was carried out to identify all - full-text, English-language articles published from 1980 to the present date and - relevant to this review. REVIEW METHODS: The following search terms were used: - takotsubo cardiomyopathy, stress-induced cardiomyopathy, and left ventricular - apical ballooning syndrome. Citation lists from identified articles were - subsequently reviewed and pertinent articles were further identified. RESULTS: - Takotsubo cardiomyopathy is typically characterized by the following: 1) acute - onset of ischemic-like chest pain or dyspnea, 2) transient apical and - mid-ventricular regional wall-motion abnormality, 3) minor elevation of cardiac - biomarkers, 4) dynamic electrocardiographic changes, and 5) the absence of - epicardial coronary artery disease. The pathogenesis of the syndrome is unknown - but has mostly been associated with acute emotional or physiologic stressors. - Dote, Sato, Tateishi, Uchida, Ishihara (J Cardiol. 21(2):203-214, 1991); Desmet, - Adriaenssens, Dens (Heart. 89(9):1027-1031, Sep., 2003); Bybee, Kara, Prasad, et - al. (Ann Intern Med. 141(11):858-865, Dec 7, 2004); Sharkey, Lesser, Zenovich, et - al. (Circulation. 111(4):472-479, Feb 1, 2005) The short and long-term prognosis - of these patients is overwhelmingly favorable and often only requires supportive - therapy. CONCLUSION: Whether an emotional or physical event precedes one's - symptoms, it is apparent that takotsubo cardiomyopathy case presentations mimic - ST-segment elevation myocardial infarction, and thus is an important entity to be - recognized by the medical community. -FAU - Sealove, Brett A -AU - Sealove BA -AD - The Zena and Michael A. Wiener Cardiovascular Institute and The Marie-Josée and - Henry R. Kravis Center for Cardiovascular Health, Mount Sinai Medical Center, New - York, NY 10029-4802, USA. brett.sealove@gmail.com -FAU - Tiyyagura, Satish -AU - Tiyyagura S -FAU - Fuster, Valentin -AU - Fuster V -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20080808 -PL - United States -TA - J Gen Intern Med -JT - Journal of general internal medicine -JID - 8605834 -SB - IM -CIN - J Gen Intern Med. 2009 Feb;24(2):286. doi: 10.1007/s11606-008-0862-z. PMID: - 19089509 -MH - Electrocardiography -MH - Female -MH - Humans -MH - Male -MH - Middle Aged -MH - Sex Distribution -MH - Stress, Psychological/complications/physiopathology -MH - Takotsubo Cardiomyopathy/*diagnosis/*physiopathology -PMC - PMC2585677 -EDAT- 2008/08/09 09:00 -MHDA- 2009/03/27 09:00 -PMCR- 2009/11/01 -CRDT- 2008/08/09 09:00 -PHST- 2008/03/10 00:00 [received] -PHST- 2008/07/03 00:00 [accepted] -PHST- 2008/06/11 00:00 [revised] -PHST- 2008/08/09 09:00 [pubmed] -PHST- 2009/03/27 09:00 [medline] -PHST- 2008/08/09 09:00 [entrez] -PHST- 2009/11/01 00:00 [pmc-release] -AID - 744 [pii] -AID - 10.1007/s11606-008-0744-4 [doi] -PST - ppublish -SO - J Gen Intern Med. 2008 Nov;23(11):1904-8. doi: 10.1007/s11606-008-0744-4. Epub - 2008 Aug 8. - -PMID- 22832424 -OWN - NLM -STAT- MEDLINE -DCOM- 20121214 -LR - 20181201 -IS - 1421-9751 (Electronic) -IS - 0008-6312 (Linking) -VI - 122 -IP - 3 -DP - 2012 -TI - A meta-analysis of randomized controlled trials appraising the efficacy and - safety of cilostazol after coronary artery stent implantation. -PG - 133-43 -LID - 10.1159/000339238 [doi] -AB - OBJECTIVES: To evaluate the impact of cilostazol on the angiographic and clinical - outcomes in patients undergoing percutaneous coronary intervention (PCI) with - stents and treated with aspirin and thienopyridine. METHODS: A total of 11 - randomized controlled trials including 8,525 patients comparing triple - antiplatelet therapy (aspirin, thienopyridine and cilostazol) with standard dual - antiplatelet therapy were included in the analysis. The primary end points were - in-segment late loss and angiographic restenosis at angiographic follow-up. - Secondary end points included mortality, stent thrombosis, target lesion - revascularization (TLR) and major adverse cardiac events (MACE). RESULTS: Triple - antiplatelet therapy was associated with a significant reduction in late loss - [weighted mean difference 0.14, 95% confidence interval (CI) 0.08-0.20; p < - 0.001] and angiographic restenosis [odds ratio (OR) 0.58, 95% CI 0.48-0.71; p < - 0.001]. Addition of cilostazol to dual antiplatelet therapy was associated with a - significant reduction in TLR (OR 0.56, 95% CI 0.41-0.77; p < 0.001) and MACE (OR - 0.72, 95% CI 0.60-0.86; p < 0.001) with no differences in mortality (p = 0.29), - stent thrombosis (p = 0.60) or bleeding episodes (p = 0.77). CONCLUSIONS: - Cilostazol in addition to dual antiplatelet therapy appears to be effective in - reducing the risk of restenosis and repeat revascularization after PCI without - any significant benefits for mortality or stent thrombosis. -CI - Copyright © 2012 S. Karger AG, Basel. -FAU - Jang, Jae-Sik -AU - Jang JS -AD - Busan Paik Hospital, University of Inje College of Medicine, Busan, Korea. - jsjang@medimail.co.kr -FAU - Jin, Han-Young -AU - Jin HY -FAU - Seo, Jeong-Sook -AU - Seo JS -FAU - Yang, Tae-Hyun -AU - Yang TH -FAU - Kim, Dae-Kyeong -AU - Kim DK -FAU - Kim, Dong-Soo -AU - Kim DS -FAU - Kim, Dong-Kie -AU - Kim DK -FAU - Seol, Sang-Hoon -AU - Seol SH -FAU - Kim, Doo-Il -AU - Kim DI -FAU - Cho, Kyoung-Im -AU - Cho KI -FAU - Kim, Bo-Hyun -AU - Kim BH -FAU - Park, Yong Hyun -AU - Park YH -FAU - Je, Hyung-Gon -AU - Je HG -FAU - Jeong, Young-Hoon -AU - Jeong YH -FAU - Kim, Won-Jang -AU - Kim WJ -FAU - Lee, Jong-Young -AU - Lee JY -FAU - Lee, Seung-Whan -AU - Lee SW -LA - eng -PT - Journal Article -PT - Meta-Analysis -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20120724 -PL - Switzerland -TA - Cardiology -JT - Cardiology -JID - 1266406 -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Pyridines) -RN - 0 (Tetrazoles) -RN - 0 (thienopyridine) -RN - A74586SNO7 (Clopidogrel) -RN - N7Z035406B (Cilostazol) -RN - OM90ZUW7M1 (Ticlopidine) -RN - R16CO5Y76E (Aspirin) -SB - IM -CIN - Cardiology. 2012;123(3):142; author reply 143-4. doi: 10.1159/000342276. PMID: - 23095279 -MH - Aspirin/therapeutic use -MH - Blood Vessel Prosthesis -MH - Blood Vessel Prosthesis Implantation/methods -MH - Cilostazol -MH - Clopidogrel -MH - Combined Modality Therapy -MH - Coronary Restenosis/*prevention & control -MH - Drug Therapy, Combination -MH - Female -MH - Graft Occlusion, Vascular/prevention & control -MH - Humans -MH - Male -MH - Middle Aged -MH - Percutaneous Coronary Intervention/*methods -MH - Platelet Aggregation Inhibitors/*therapeutic use -MH - Pyridines/therapeutic use -MH - Randomized Controlled Trials as Topic -MH - *Stents -MH - Tetrazoles/*therapeutic use -MH - Ticlopidine/analogs & derivatives/therapeutic use -MH - Treatment Outcome -EDAT- 2012/07/27 06:00 -MHDA- 2012/12/15 06:00 -CRDT- 2012/07/27 06:00 -PHST- 2012/03/16 00:00 [received] -PHST- 2012/04/25 00:00 [accepted] -PHST- 2012/07/27 06:00 [entrez] -PHST- 2012/07/27 06:00 [pubmed] -PHST- 2012/12/15 06:00 [medline] -AID - 000339238 [pii] -AID - 10.1159/000339238 [doi] -PST - ppublish -SO - Cardiology. 2012;122(3):133-43. doi: 10.1159/000339238. Epub 2012 Jul 24. - -PMID- 21784380 -OWN - NLM -STAT- MEDLINE -DCOM- 20111110 -LR - 20161125 -IS - 1933-2874 (Print) -IS - 1876-4789 (Linking) -VI - 5 -IP - 4 -DP - 2011 Jul-Aug -TI - Fatal cardiac atherosclerosis in a child 10 years after liver transplantation: a - case report and a review. -PG - 329-32 -LID - 10.1016/j.jacl.2011.05.002 [doi] -AB - We hereby review liver transplantation for homozygous familial - hypercholesterolemia and report the case of a 14-year-old girl presenting with - severe bilateral coronary ostial stenosis and tight supra-valvular aortic - narrowing 10 years after liver transplantation. Despite normalization of the - lipids after liver transplantation, the patient showed evidence of severe cardiac - atherosclerosis 10 years later and died of apparent sepsis. -CI - Copyright © 2011 National Lipid Association. Published by Elsevier Inc. All - rights reserved. -FAU - El-Rassi, Issam -AU - El-Rassi I -AD - Hotel-Dieu de France Hospital, Boulevard Naccach, PO Box 166830, Beirut, Lebanon. - issam.rassi@gmail.com -FAU - Chehab, Ghassan -AU - Chehab G -FAU - Saliba, Zakhia -AU - Saliba Z -FAU - Alawe, Abdallah -AU - Alawe A -FAU - Jebara, Victor -AU - Jebara V -LA - eng -PT - Case Reports -PT - Journal Article -PT - Review -DEP - 20110520 -PL - United States -TA - J Clin Lipidol -JT - Journal of clinical lipidology -JID - 101300157 -RN - 0 (Lipids) -RN - 83HN0GTJ6D (Cyclosporine) -SB - IM -MH - Adolescent -MH - Aortic Valve Stenosis/*complications/diagnostic imaging -MH - Atherosclerosis/*complications -MH - Coronary Stenosis/*complications -MH - Cyclosporine/therapeutic use -MH - Fatal Outcome -MH - Female -MH - Homozygote -MH - Humans -MH - Hyperlipoproteinemia Type II/*complications/drug therapy/surgery -MH - Lipids/*blood -MH - Liver Transplantation -MH - Radiography -EDAT- 2011/07/26 06:00 -MHDA- 2011/11/11 06:00 -CRDT- 2011/07/26 06:00 -PHST- 2011/02/14 00:00 [received] -PHST- 2011/04/28 00:00 [revised] -PHST- 2011/05/09 00:00 [accepted] -PHST- 2011/07/26 06:00 [entrez] -PHST- 2011/07/26 06:00 [pubmed] -PHST- 2011/11/11 06:00 [medline] -AID - S1933-2874(11)00604-0 [pii] -AID - 10.1016/j.jacl.2011.05.002 [doi] -PST - ppublish -SO - J Clin Lipidol. 2011 Jul-Aug;5(4):329-32. doi: 10.1016/j.jacl.2011.05.002. Epub - 2011 May 20. - -PMID- 17999875 -OWN - NLM -STAT- MEDLINE -DCOM- 20080208 -LR - 20211020 -IS - 1523-3782 (Print) -IS - 1523-3782 (Linking) -VI - 9 -IP - 6 -DP - 2007 Nov -TI - New insights into the role of HDL as an anti-inflammatory agent in the prevention - of cardiovascular disease. -PG - 493-8 -AB - Several known functions of high-density lipoproteins (HDLs) may contribute to - their ability to protect against atherosclerosis. The best known of these - functions is the ability to promote cholesterol efflux from cells in a process - that may minimize the accumulation of foam cells in the artery wall. However, - HDLs have additional properties, including antioxidant, anti-inflammatory, and - antithrombotic effects, that may also be anti-atherogenic. Recent in vivo studies - in several animal models have demonstrated that HDLs can inhibit acute and - chronic vascular inflammation. The fact that these effects can be achieved with - very low doses of reconstituted discoidal HDL or even lipid-free apolipoprotein - A-I suggests that they may reflect activity of a minor, highly active HDL - subpopulation. These results have potentially important clinical implications in - regard to managing the acute vascular inflammation states that accompany acute - coronary syndrome and acute ischemic stroke. -FAU - Barter, Philip J -AU - Barter PJ -AD - The Heart Research Institute, 114 Pyrmont Bridge Road, Camperdown, Sydney 2050, - Australia. barterp@hri.org.au -FAU - Puranik, Rajesh -AU - Puranik R -FAU - Rye, Kerry-Anne -AU - Rye KA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Curr Cardiol Rep -JT - Current cardiology reports -JID - 100888969 -RN - 0 (APOA1 protein, human) -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Apolipoprotein A-I) -RN - 0 (Cholesterol, HDL) -SB - IM -MH - Anti-Inflammatory Agents/metabolism/*therapeutic use -MH - Apolipoprotein A-I -MH - Cardiovascular Diseases/blood/physiopathology/*prevention & control -MH - Cholesterol, HDL/metabolism/*therapeutic use -MH - Endothelium, Vascular -MH - Humans -MH - Inflammation/*drug therapy -RF - 46 -EDAT- 2007/11/15 09:00 -MHDA- 2008/02/09 09:00 -CRDT- 2007/11/15 09:00 -PHST- 2007/11/15 09:00 [pubmed] -PHST- 2008/02/09 09:00 [medline] -PHST- 2007/11/15 09:00 [entrez] -AID - 10.1007/BF02938394 [doi] -PST - ppublish -SO - Curr Cardiol Rep. 2007 Nov;9(6):493-8. doi: 10.1007/BF02938394. - -PMID- 21792462 -OWN - NLM -STAT- MEDLINE -DCOM- 20120109 -LR - 20181201 -IS - 2567-689X (Electronic) -IS - 0340-6245 (Linking) -VI - 106 -IP - 2 -DP - 2011 Aug -TI - The genetic basis of platelet responsiveness to clopidogrel. A critical review of - the literature. -PG - 203-10 -LID - 10.1160/TH11-04-0228 [doi] -AB - Clopidogrel reduces ischaemic complications in a wide range of patients with - coronary artery disease. However, there is much inter-individual variation in - clopidogrel-induced platelet inhibition, and a substantial proportion of patients - will exhibit non-responsiveness to clopidogrel. Multiple studies have - demonstrated an association between the presence of genetic polymorphisms - associated with suboptimal clopidogrel-active metabolite generation, decreased - platelet responsiveness, and adverse clinical outcomes. However, it is not clear - to what extent the genetic polymorphisms account for the observed variability in - response to clopidogrel. In this review we provide a critical summary of the - available evidence linking genetic factors with response to clopidogrel, and - discuss the clinical implications of this association. -FAU - Fefer, Paul -AU - Fefer P -AD - Leviev Heart Center, Chaim Sheba Medical Center, Tel Hashomer and Sackler Faculty - of Medicine, Tel Aviv University, Tel Aviv, Israel. -FAU - Matetzky, Shlomi -AU - Matetzky S -LA - eng -PT - Journal Article -PT - Review -DEP - 20110712 -PL - Germany -TA - Thromb Haemost -JT - Thrombosis and haemostasis -JID - 7608063 -RN - 0 (Platelet Aggregation Inhibitors) -RN - A74586SNO7 (Clopidogrel) -RN - EC 1.14.14.1 (Aryl Hydrocarbon Hydroxylases) -RN - EC 1.14.14.1 (CYP2C19 protein, human) -RN - EC 1.14.14.1 (Cytochrome P-450 CYP2C19) -RN - EC 3.1.8.1 (Aryldialkylphosphatase) -RN - EC 3.1.8.1 (PON1 protein, human) -RN - OM90ZUW7M1 (Ticlopidine) -SB - IM -MH - Alleles -MH - Aryl Hydrocarbon Hydroxylases/genetics/metabolism -MH - Aryldialkylphosphatase/genetics/metabolism -MH - Clopidogrel -MH - Cytochrome P-450 CYP2C19 -MH - Humans -MH - Pharmacogenetics -MH - Platelet Aggregation/*drug effects/*genetics -MH - Platelet Aggregation Inhibitors/pharmacokinetics/*pharmacology -MH - Polymorphism, Genetic -MH - Ticlopidine/*analogs & derivatives/pharmacokinetics/pharmacology -EDAT- 2011/07/28 06:00 -MHDA- 2012/01/10 06:00 -CRDT- 2011/07/28 06:00 -PHST- 2011/04/12 00:00 [received] -PHST- 2011/06/30 00:00 [accepted] -PHST- 2011/07/28 06:00 [entrez] -PHST- 2011/07/28 06:00 [pubmed] -PHST- 2012/01/10 06:00 [medline] -AID - 11-04-0228 [pii] -AID - 10.1160/TH11-04-0228 [doi] -PST - ppublish -SO - Thromb Haemost. 2011 Aug;106(2):203-10. doi: 10.1160/TH11-04-0228. Epub 2011 Jul - 12. - -PMID- 18385533 -OWN - NLM -STAT- MEDLINE -DCOM- 20080918 -LR - 20190608 -IS - 1340-3478 (Print) -IS - 1340-3478 (Linking) -VI - 15 -IP - 2 -DP - 2008 Apr -TI - Antiatherogenic functionality of high density lipoprotein: how much versus how - good. -PG - 52-62 -AB - Plasma concentration of high density lipoprotein (HDL) is one of the most - reliable negative risk factors for CVD. There is however convincing experimental - and clinical evidence that plasma concentration of HDL does not convey the full - picture of atheroprotective properties of HDL. HDL functionality, i.e. the - ability of HDL to perform its many atheroprotective functions, is partly - independent of HDL concentration and may be as important, if not more important, - in determining the atheroprotective capacity of HDL. The capacity of HDL to - support cholesterol efflux, its anti-inflammatory, anti-oxidant, anti-thrombotic - and other atheroprotective functions are affected dramatically in conditions like - coronary artery disease, chronic and acute inflammation, diabetes as well as - through various interventions. The mechanisms connecting changes in HDL - functionality to HDL structure are only beginning to emerge. Modifications of HDL - proteins and lipids, such as advanced glycation and oxidation, changes in HDL - composition and size of HDL particles, changes in abundance of various proteins - and lipids carried by HDL are among factors affecting HDL functionality. A single - common denominator reflecting the multiple HDL functions is yet to be found and - may not exist leaving direct measurements of each HDL function as the way to - assess atheroprotective capacity of HDL. -FAU - Sviridov, Dmitri -AU - Sviridov D -AD - Baker Heart Research Institute, St. Kilda Road Central, Melbourne, Victoria 8008, - Australia. Dmitri.Sviridov@baker.edu.au -FAU - Mukhamedova, Nigora -AU - Mukhamedova N -FAU - Remaley, Alan T -AU - Remaley AT -FAU - Chin-Dusting, Jaye -AU - Chin-Dusting J -FAU - Nestel, Paul -AU - Nestel P -LA - eng -PT - Journal Article -PT - Research Support, Non-U.S. Gov't -PT - Review -DEP - 20080403 -PL - Japan -TA - J Atheroscler Thromb -JT - Journal of atherosclerosis and thrombosis -JID - 9506298 -RN - 0 (Lipoproteins, HDL) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - Atherosclerosis/*physiopathology/*prevention & control -MH - Cholesterol/metabolism -MH - Humans -MH - Inflammation/metabolism -MH - Lipoproteins, HDL/*metabolism -MH - Oxidation-Reduction -MH - Thrombosis/physiopathology -RF - 100 -EDAT- 2008/04/04 09:00 -MHDA- 2008/09/19 09:00 -CRDT- 2008/04/04 09:00 -PHST- 2008/04/04 09:00 [pubmed] -PHST- 2008/09/19 09:00 [medline] -PHST- 2008/04/04 09:00 [entrez] -AID - JST.JSTAGE/jat/E571 [pii] -AID - 10.5551/jat.e571 [doi] -PST - ppublish -SO - J Atheroscler Thromb. 2008 Apr;15(2):52-62. doi: 10.5551/jat.e571. Epub 2008 Apr - 3. - -PMID- 21035586 -OWN - NLM -STAT- MEDLINE -DCOM- 20101122 -LR - 20101101 -IS - 1555-7162 (Electronic) -IS - 0002-9343 (Linking) -VI - 123 -IP - 11 -DP - 2010 Nov -TI - Sporting events affect spectators' cardiovascular mortality: it is not just a - game. -PG - 972-7 -LID - 10.1016/j.amjmed.2010.03.026 [doi] -AB - Physiologic and clinical triggers, including mental stress, anxiety, and anger, - often precipitate acute myocardial infarction and cardiovascular death. Sporting - events can acutely increase cardiovascular event and death rates. A greater - impact is observed in patients with known coronary artery disease and when - stressful features are present, including a passionate fan, a high-stakes game, a - high-intensity game, a loss, and a loss played at home. Sporting events affect - cardiovascular health through neuroendocrine responses and possibly an increase - in high-risk behaviors. Acute mental stress increases the activity of the - hypothalamic-pituitary-adrenocortical axis and the sympathetic-adrenal-medullary - system while impairing vagal tone and endothelial function. Collectively, these - mechanisms increase myocardial oxygen demand and decrease myocardial oxygen - supply while also increasing the risk of arrhythmias and thrombosis. Measures can - be taken to reduce cardiovascular risk, including the use of beta-blockers and - aspirin, stress management, transcendental meditation, and avoidance of high-risk - activities, such as smoking, eating fatty foods, overeating, and abusing alcohol - and illicit drugs. Sporting events have the potential to adversely affect - spectators' cardiovascular health, and protective measures should be considered. -CI - Copyright © 2010 Elsevier Inc. All rights reserved. -FAU - Leeka, Justin -AU - Leeka J -AD - Heart Institute, Good Samaritan Hospital, Los Angeles, CA, USA. -FAU - Schwartz, Bryan G -AU - Schwartz BG -FAU - Kloner, Robert A -AU - Kloner RA -LA - eng -PT - Journal Article -PT - Review -PL - United States -TA - Am J Med -JT - The American journal of medicine -JID - 0267200 -SB - IM -MH - Cardiovascular Diseases/etiology/*mortality/physiopathology -MH - Football/psychology -MH - Health Behavior -MH - Hockey/psychology -MH - Humans -MH - Hypothalamo-Hypophyseal System/physiopathology -MH - Pituitary-Adrenal System/physiopathology -MH - Risk Factors -MH - Soccer/psychology -MH - Sports/physiology/*psychology -MH - Stress, Psychological/physiopathology -EDAT- 2010/11/03 06:00 -MHDA- 2010/12/14 06:00 -CRDT- 2010/11/02 06:00 -PHST- 2010/01/20 00:00 [received] -PHST- 2010/02/10 00:00 [revised] -PHST- 2010/03/15 00:00 [accepted] -PHST- 2010/11/02 06:00 [entrez] -PHST- 2010/11/03 06:00 [pubmed] -PHST- 2010/12/14 06:00 [medline] -AID - S0002-9343(10)00486-9 [pii] -AID - 10.1016/j.amjmed.2010.03.026 [doi] -PST - ppublish -SO - Am J Med. 2010 Nov;123(11):972-7. doi: 10.1016/j.amjmed.2010.03.026. - -PMID- 20374257 -OWN - NLM -STAT- MEDLINE -DCOM- 20101102 -LR - 20220408 -IS - 1440-1681 (Electronic) -IS - 0305-1870 (Linking) -VI - 37 -IP - 7 -DP - 2010 Jul -TI - Rate-limiting factors of cholesterol efflux in reverse cholesterol transport: - acceptors and donors. -PG - 703-9 -LID - 10.1111/j.1440-1681.2010.05386.x [doi] -AB - 1. Plasma levels of high-density lipoprotein (HDL) are believed to be inversely - related to coronary artery disease. High-density lipoprotein plays a key role in - the process of reverse cholesterol transport, by which HDL is able to extract - excess cholesterol from peripheral tissues and transfer it to the liver for - biliary excretion. 2. Efflux of lipids (cholesterol and phospholipids) is the - first step in reverse cholesterol transport. Several cellular membrane - transporters, including ABCA1 and ABCG1, as well as scavenger receptor (SR)-BI - receptor, are believed to facilitate the active efflux of cholesterol to - lipid-poor apolipoprotein A-I and mature HDL, respectively. Furthermore, - overexpression or deletion of one or more specific genes supports the view that - HDL is involved in cholesterol efflux. 3. In conclusion, current evidence - supports a critical role for HDL in atheroprotection via an active efflux pathway - through reverse cholesterol transport, with the substantial support of - appropriate functions of cell donors. -FAU - Fu, Ying -AU - Fu Y -AD - Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia. - Ying.Fu@Bakeridi.edu.au -LA - eng -PT - Journal Article -PT - Review -DEP - 20100330 -PL - Australia -TA - Clin Exp Pharmacol Physiol -JT - Clinical and experimental pharmacology & physiology -JID - 0425076 -RN - 0 (ABCA1 protein, human) -RN - 0 (ABCA2 protein, human) -RN - 0 (ATP Binding Cassette Transporter 1) -RN - 0 (ATP-Binding Cassette Transporters) -RN - 0 (Lipoproteins, HDL) -RN - 0 (Phospholipids) -RN - 0 (Receptors, Scavenger) -RN - 97C5T2UQ7J (Cholesterol) -SB - IM -MH - ATP Binding Cassette Transporter 1 -MH - ATP-Binding Cassette Transporters/*metabolism -MH - Atherosclerosis/*metabolism -MH - Biological Transport -MH - Cholesterol/*metabolism -MH - Humans -MH - Lipoproteins, HDL/blood/*metabolism -MH - Phospholipids/metabolism -MH - Receptors, Scavenger/metabolism -EDAT- 2010/04/09 06:00 -MHDA- 2010/11/03 06:00 -CRDT- 2010/04/09 06:00 -PHST- 2010/04/09 06:00 [entrez] -PHST- 2010/04/09 06:00 [pubmed] -PHST- 2010/11/03 06:00 [medline] -AID - CEP5386 [pii] -AID - 10.1111/j.1440-1681.2010.05386.x [doi] -PST - ppublish -SO - Clin Exp Pharmacol Physiol. 2010 Jul;37(7):703-9. doi: - 10.1111/j.1440-1681.2010.05386.x. Epub 2010 Mar 30. - -PMID- 23672430 -OWN - NLM -STAT- MEDLINE -DCOM- 20130919 -LR - 20130722 -IS - 1365-3083 (Electronic) -IS - 0300-9475 (Linking) -VI - 78 -IP - 2 -DP - 2013 Aug -TI - Atrial fibrillation: inflammation in disguise? -PG - 112-9 -LID - 10.1111/sji.12061 [doi] -AB - Atrial fibrillation is highly prevalent, and affected patients are at an - increased risk of a number of complications, including heart failure and - thrombo-embolism. Over the past years, there has been increasing interest in the - role of inflammatory processes in atrial fibrillation, from the first occurrence - of the arrhythmia to dreaded complications such as strokes or peripheral emboli. - As the standard drug combination which aims at rate control and anticoagulation - only offers partial protection against complications, newer agents are needed to - optimize treatment. In this paper, we review recent knowledge regarding the - impact of inflammation on the occurrence, recurrence, perpetuation and - complications of the arrhythmia, as well as the role of anti-inflammatory - therapies in the treatment for the disease. -CI - © 2013 John Wiley & Sons Ltd. -FAU - Lappegård, K T -AU - Lappegård KT -AD - Coronary Care Unit, Division of Internal Medicine, Nordland Hospital, Bodø, - Norway. knut.tore.lappegard@gmail.com -FAU - Hovland, A -AU - Hovland A -FAU - Pop, G A M -AU - Pop GA -FAU - Mollnes, T E -AU - Mollnes TE -LA - eng -PT - Journal Article -PT - Review -PL - England -TA - Scand J Immunol -JT - Scandinavian journal of immunology -JID - 0323767 -RN - 0 (Anti-Arrhythmia Agents) -RN - 0 (Anti-Inflammatory Agents) -RN - 0 (Anticoagulants) -SB - IM -MH - Animals -MH - Anti-Arrhythmia Agents/therapeutic use -MH - Anti-Inflammatory Agents/therapeutic use -MH - Anticoagulants/therapeutic use -MH - Arrhythmias, Cardiac/drug therapy/etiology/*physiopathology -MH - Atrial Fibrillation/complications/drug therapy/*physiopathology -MH - Heart Failure/drug therapy/etiology/*physiopathology -MH - Humans -MH - Inflammation/drug therapy -MH - Stroke/drug therapy/etiology/*physiopathology -MH - Thromboembolism/drug therapy/etiology/*physiopathology -EDAT- 2013/05/16 06:00 -MHDA- 2013/09/21 06:00 -CRDT- 2013/05/16 06:00 -PHST- 2013/04/11 00:00 [received] -PHST- 2013/05/03 00:00 [accepted] -PHST- 2013/05/16 06:00 [entrez] -PHST- 2013/05/16 06:00 [pubmed] -PHST- 2013/09/21 06:00 [medline] -AID - 10.1111/sji.12061 [doi] -PST - ppublish -SO - Scand J Immunol. 2013 Aug;78(2):112-9. doi: 10.1111/sji.12061. - -PMID- 20032988 -OWN - NLM -STAT- MEDLINE -DCOM- 20100607 -LR - 20151119 -IS - 1476-5489 (Electronic) -IS - 0955-9930 (Linking) -VI - 22 -IP - 2 -DP - 2010 Mar-Apr -TI - The endothelial cell in health and disease: its function, dysfunction, - measurement and therapy. -PG - 77-90 -LID - 10.1038/ijir.2009.59 [doi] -AB - Endothelial cells have numerous endocrine functions and contribute to a variety - of processes, including penile erection and vasodilation. Endothelial dysfunction - is associated with cardiovascular risk factors and has been implicated in the - pathogenesis of atherosclerosis and ED. This study reviews endothelial function, - in addition to endothelial dysfunction and its role in atherosclerosis and ED. - Measurement of endothelial function is reviewed, including catheter-based - methods, venous occlusion plethysmography, high-frequency ultrasound, peripheral - arterial tonometry, digital pulse amplitude tonometry, digital thermal - monitoring, the L-arginine test and measurement of compounds released by - endothelial cells. Therapy and medications that improve endothelial function are - reviewed. As the scientific community learns more about the importance of the - endothelium, it is increasingly important for the clinician to understand - endothelial function, dysfunction, measurement of endothelial function and - therapies that affect this remarkable cell type. -FAU - Schwartz, B G -AU - Schwartz BG -AD - Heart Institute, Good Samaritan Hospital, Los Angeles, California 90017, USA. -FAU - Economides, C -AU - Economides C -FAU - Mayeda, G S -AU - Mayeda GS -FAU - Burstein, S -AU - Burstein S -FAU - Kloner, R A -AU - Kloner RA -LA - eng -PT - Journal Article -PT - Review -DEP - 20091224 -PL - England -TA - Int J Impot Res -JT - International journal of impotence research -JID - 9007383 -RN - 0 (Enzyme Inhibitors) -RN - 0 (Phosphodiesterase 5 Inhibitors) -RN - 31C4KY9ESH (Nitric Oxide) -RN - 94ZLA3W45F (Arginine) -SB - IM -MH - Arginine -MH - *Atherosclerosis/drug therapy/etiology/physiopathology -MH - Catheterization -MH - Constriction -MH - Coronary Vessels -MH - Endothelial Cells/cytology/drug effects/*physiology -MH - Enzyme Inhibitors/therapeutic use -MH - *Erectile Dysfunction/drug therapy/etiology/physiopathology -MH - Humans -MH - Male -MH - Manometry -MH - Nitric Oxide/pharmacology -MH - Penile Erection/drug effects/physiology -MH - Phosphodiesterase 5 Inhibitors -MH - Plethysmography -MH - Vasodilation/drug effects/physiology -MH - Veins -RF - 121 -EDAT- 2009/12/25 06:00 -MHDA- 2010/06/09 06:00 -CRDT- 2009/12/25 06:00 -PHST- 2009/12/25 06:00 [entrez] -PHST- 2009/12/25 06:00 [pubmed] -PHST- 2010/06/09 06:00 [medline] -AID - ijir200959 [pii] -AID - 10.1038/ijir.2009.59 [doi] -PST - ppublish -SO - Int J Impot Res. 2010 Mar-Apr;22(2):77-90. doi: 10.1038/ijir.2009.59. Epub 2009 - Dec 24. - -PMID- 17948687 -OWN - NLM -STAT- MEDLINE -DCOM- 20071228 -LR - 20131121 -IS - 0047-1852 (Print) -IS - 0047-1852 (Linking) -VI - Suppl 5 Pt 2 -DP - 2007 Sep 28 -TI - [Coronary thrombotic angina]. -PG - 24-8 -FAU - Kaikita, Koichi -AU - Kaikita K -AD - Department of Cardiovascular Medicine, Graduate School of Medical Sciences, - Kumamoto University. -FAU - Ogawa, Hisao -AU - Ogawa H -LA - jpn -PT - Journal Article -PT - Review -PL - Japan -TA - Nihon Rinsho -JT - Nihon rinsho. Japanese journal of clinical medicine -JID - 0420546 -RN - 0 (Adrenergic beta-Antagonists) -RN - 0 (Calcium Channel Blockers) -RN - 0 (Fibrinolytic Agents) -RN - 0 (Nitro Compounds) -RN - 0 (Vasodilator Agents) -RN - 260456HAM0 (Nicorandil) -SB - IM -MH - Adrenergic beta-Antagonists/therapeutic use -MH - Angina Pectoris/diagnosis/*etiology/physiopathology/therapy -MH - Calcium Channel Blockers/therapeutic use -MH - Coronary Angiography -MH - Coronary Artery Bypass -MH - Coronary Thrombosis/*complications -MH - Diagnosis, Differential -MH - Electrocardiography -MH - Fibrinolytic Agents/therapeutic use -MH - Humans -MH - Intra-Aortic Balloon Pumping -MH - Nicorandil/therapeutic use -MH - Nitro Compounds/therapeutic use -MH - Vasodilator Agents/therapeutic use -RF - 8 -EDAT- 2007/10/24 09:00 -MHDA- 2007/12/29 09:00 -CRDT- 2007/10/24 09:00 -PHST- 2007/10/24 09:00 [pubmed] -PHST- 2007/12/29 09:00 [medline] -PHST- 2007/10/24 09:00 [entrez] -PST - ppublish -SO - Nihon Rinsho. 2007 Sep 28;Suppl 5 Pt 2:24-8. - -PMID- 22360514 -OWN - NLM -STAT- MEDLINE -DCOM- 20121017 -LR - 20190728 -IS - 1873-4286 (Electronic) -IS - 1381-6128 (Linking) -VI - 18 -IP - 12 -DP - 2012 -TI - A critical appraisal of the functional evolution of P2Y12 antagonists as - antiplatelet drugs. -PG - 1625-34 -AB - P2Y12 receptor mediated inhibition of platelet aggregation is one of the most - explored and exploited pathways in antiplatelet drug therapy to prevent ischemic - events in patients undergoing percutaneous coronary intervention (PCI) for the - treatment of the acute coronary syndrome (ACS). Ticlopidine, Clopidogrel, - Prasugrel, Ticagrelor, Cangrelor and Elinogrel are the P2Y12 inhibitors that act - as antiplatelet drugs. In this review, the features of these drugs and the - factors reported to be responsible for drug resistance or drug ineffectiveness - were described. The features like drug metabolism, reversible or irreversible - binding of drugs to their target protein and the mode of administration were - observed to evolve along with the antiplatelet drugs. These features also include - the drug-drug interactions, the pharmacogenetics and pharmacodynamics of P2Y12 - inhibitors. We attempted to critically analyze how the desirable features were - met by the P2Y12 inhibitors in the course of time. This review provides an - overview of the evolution of P2Y12 inhibitors and may guide the researchers to - develop better antiplatelet drugs in the future. -FAU - Fayaz, S M A -AU - Fayaz SM -AD - School of Biotechnology, National Institute of Technology Calicut, - Calicut-673601, Kerala, India. -FAU - Rajanikant, G K -AU - Rajanikant GK -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Pharm Des -JT - Current pharmaceutical design -JID - 9602487 -RN - 0 (P2RY12 protein, human) -RN - 0 (Platelet Aggregation Inhibitors) -RN - 0 (Purinergic P2Y Receptor Antagonists) -RN - 0 (Receptors, Purinergic P2Y12) -SB - IM -MH - Coronary Thrombosis/prevention & control -MH - Drug Interactions -MH - Humans -MH - Platelet Aggregation Inhibitors/*metabolism/*pharmacology/therapeutic use -MH - Purinergic P2Y Receptor Antagonists/*metabolism/*pharmacology/therapeutic use -MH - Receptors, Purinergic P2Y12/chemistry/genetics/metabolism -EDAT- 2012/03/01 06:00 -MHDA- 2012/10/18 06:00 -CRDT- 2012/02/25 06:00 -PHST- 2011/10/31 00:00 [received] -PHST- 2011/12/26 00:00 [accepted] -PHST- 2012/02/25 06:00 [entrez] -PHST- 2012/03/01 06:00 [pubmed] -PHST- 2012/10/18 06:00 [medline] -AID - CPD-EPUB-20120224-001 [pii] -AID - 10.2174/138161212799958558 [doi] -PST - ppublish -SO - Curr Pharm Des. 2012;18(12):1625-34. doi: 10.2174/138161212799958558. - -PMID- 18393913 -OWN - NLM -STAT- MEDLINE -DCOM- 20080718 -LR - 20191027 -IS - 1570-1611 (Print) -IS - 1570-1611 (Linking) -VI - 6 -IP - 2 -DP - 2008 Apr -TI - Hormone replacement therapy and stroke. -PG - 112-23 -AB - Stroke is the third most common cause of death in women and a major cause of - disability. Stroke occurs in older age in women compared with men. High - premenopausal estrogen concentrations in women are thought to be protective - against stroke and cardiovascular disease. Estrogens are essential for normal - reproductive function and they exert complex and diverse non reproductive actions - on multiple tissues such as neuroprotective effects, vasodilatation, improved - vascular reactivity, antithrombotic effects and lipid lowering effects. After - menopause estrogen concentrations are depleted and in the past estrogen - replacement therapy was considered as a potential protective agent against both - cardiovascular disease and stroke. Although the use of hormone therapy was - originally associated with a reduction in the risk of heart disease by about 50% - in observational studies, the results regarding stroke have been less clear. In - order to investigate the effect of hormone therapy on stroke risk, randomized - controlled trials of cardio-and/or cerebrovascular-disease prevention in women - with established heart disease have been designed. The Heart Estrogen-Progestin - Replacement Study included stroke as secondary outcome. This study did not show - any differences in myocardial infarction (MI) or coronary death (HR 0.99; 95%CI - 0.80-1.22) and in stroke rate. In another study, the Women Estrogen Stroke Trial, - 17 beta estradiol 1 mg/placebo was administered to women with previous ischemic - stroke or transient ischaemic attack (TIA) having a mean age 71. No differences - in stroke rate (RR 1.1; 95% CI 0.8-1.4) and in mortality rate (RR 1.2; 95% CI - 0.8-1.8) were found, while a trend showing an increased rate of fatal strokes (RR - 2.9; 95% CI 0.9-9.0) and for more severe non-fatal strokes (% patients with final - National Institutes of Health Stroke Scale (NIHSS) 0-1: 19 % vs. 33%; p = 0.12) - was observed. The Women's Health Initiative, a primary prevention study, where - conjugated equine estrogen (CEE) plus medroxyprogesterone acetate/placebo was - utilized, was stopped because of an excess in breast cancer and increased stroke - rates (RR 1.4; 95% CI 1.1-1.8). Recently, a meta-analysis including 39,769 women - participating in 28 trials has been published. Twelve studies were of secondary - prevention and the overall stroke rate was 2%. In the hormone replacement therapy - (HRT) arm there was a 29% increased rate of ischemic stroke (Number Needed to - Harm, NNH:147). Furthermore, a 56% increased rate of death or dependency after - stroke and a tendency of more fatal stroke were observed. Additionally, a higher - stroke risk was reported in the first year of treatment. CONCLUSIONS: There seems - to be no indication for hormone replacement therapy in the prevention of stroke - in women. Further studies are needed to discover why estrogens have different - effects on the heart and brain. Conventional risk-factors which could increase - the risk of estrogen therapy need to be identified and as well as more - restrictive inclusion and exclusion criteria such as coagulation parameters and - intimal thickness should be adopted before new randomized trials are started. -FAU - Billeci, Antonia M R -AU - Billeci AM -AD - Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, - Ospedale S.M. della Misericordia, Sant'Andrea delle Fratte, 06129 Perugia, Italy. - antobilly@yahoo.it -FAU - Paciaroni, Maurizio -AU - Paciaroni M -FAU - Caso, Valeria -AU - Caso V -FAU - Agnelli, Giancarlo -AU - Agnelli G -LA - eng -PT - Journal Article -PT - Review -PL - United Arab Emirates -TA - Curr Vasc Pharmacol -JT - Current vascular pharmacology -JID - 101157208 -SB - IM -MH - Cardiovascular Diseases/prevention & control -MH - Drug Administration Routes -MH - *Estrogen Replacement Therapy/adverse effects -MH - Female -MH - Humans -MH - Male -MH - Postmenopause -MH - Risk -MH - Sex Factors -MH - Stroke/*prevention & control -MH - *Women's Health -RF - 154 -EDAT- 2008/04/09 09:00 -MHDA- 2008/07/19 09:00 -CRDT- 2008/04/09 09:00 -PHST- 2008/04/09 09:00 [pubmed] -PHST- 2008/07/19 09:00 [medline] -PHST- 2008/04/09 09:00 [entrez] -AID - 10.2174/157016108783955338 [doi] -PST - ppublish -SO - Curr Vasc Pharmacol. 2008 Apr;6(2):112-23. doi: 10.2174/157016108783955338. diff --git a/sources/new/SCOPUS/scopus_collection.csv b/sources/new/SCOPUS/scopus_collection.csv deleted file mode 100644 index bdee043d8..000000000 --- a/sources/new/SCOPUS/scopus_collection.csv +++ /dev/null @@ -1,201 +0,0 @@ -"Authors","Author full names","Author(s) ID","Title","Year","Source title","Volume","Issue","Art. No.","Page start","Page end","Page count","Cited by","DOI","Link","Affiliations","Authors with affiliations","Abstract","Author Keywords","Index Keywords","Molecular Sequence Numbers","Chemicals/CAS","Tradenames","Manufacturers","Funding Details","Funding Texts","References","Correspondence Address","Editors","Publisher","Sponsors","Conference name","Conference date","Conference location","Conference code","ISSN","ISBN","CODEN","PubMed ID","Language of Original Document","Abbreviated Source Title","Document Type","Publication Stage","Open Access","Source","EID" -"Lim W.M.; Kumar S.; Donthu N.","Lim, Weng Marc (57193912670); Kumar, Satish (57992552600); Donthu, Naveen (6602336941)","57193912670; 57992552600; 6602336941","How to combine and clean bibliometric data and use bibliometric tools synergistically: Guidelines using metaverse research","2024","Journal of Business Research","182","","114760","","","","86","10.1016/j.jbusres.2024.114760","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196286855&doi=10.1016%2fj.jbusres.2024.114760&partnerID=40&md5=8938d470a436c8b3467716f3ca8ff67b","Sunway Business School, Sunway University, Sunway City, Selangor, Malaysia; Faculty of Business, Design and Arts, Swinburne University of Technology, Sarawak, Kuching, Malaysia; School of Business, Law and Entrepreneurship, Swinburne University of Technology, Hawthorn, VIC, Australia; Indian Institute of Management Nagpur, Nagpur, India; Department of Marketing, J. Mack Robinson College of Business, Georgia State University, Atlanta, GA, United States","Lim W.M., Sunway Business School, Sunway University, Sunway City, Selangor, Malaysia, Faculty of Business, Design and Arts, Swinburne University of Technology, Sarawak, Kuching, Malaysia, School of Business, Law and Entrepreneurship, Swinburne University of Technology, Hawthorn, VIC, Australia; Kumar S., Indian Institute of Management Nagpur, Nagpur, India; Donthu N., Department of Marketing, J. Mack Robinson College of Business, Georgia State University, Atlanta, GA, United States","Bibliometrics (or scientometrics) is a powerful technique to assess the trajectory of scientific research. Building on the Journal of Business Research's seminal guides for bibliometric analysis—i.e., “How to conduct a bibliometric analysis: An overview and guidelines” and “Guidelines for advancing theory and practice through bibliometric research”—and using metaverse research as a case, this article presents in-depth procedural guidelines for (i) combing and cleaning bibliometric data from multiple databases (Scopus and Web of Science) and (ii) conducting bibliometric analysis using multiple tools (bibliometrix and VOSviewer). Besides serving as a guide to harness the potential of bibliometrics for insightful assessments of scientific research, this article provides noteworthy insights into various features of the metaverse. This includes an examination of decentralized systems and the integration of digital assets, alongside innovations, the influence of industrial revolutions, and ethical and sustainable development. The dynamics of digital identity, ownership, and business models are explored in tandem with engagement strategies and multi-disciplinary perspectives of the metaverse. This comprehensive analysis also addresses metaverse challenges, market behaviors, and marketing strategies. Collectively, these insights offer a robust foundation for scholars, practitioners, and policymakers to shape the future of the metaverse with clarity, purpose, and impact. © 2024 The Authors","Bibliographic coupling; Bibliometric analysis; Bibliometrics; Bibliometrix; Biblioshiny; Co-citation analysis; Co-occurrence analysis; Metaverse; Performance analysis; R; RStudio; Science mapping; Scientometric analysis; Scientometrics; Scopus; Trend analysis; VOSviewer; Web of Science","","","","","","","","Aharon D.Y., Demir E., Siev S., Real returns from unreal world? Market reaction to Metaverse disclosures, Research in International Business and Finance, 63, (2022); Ahn S.J., Kim J., Kim J., The future of advertising research in virtual, augmented, and extended realities, International Journal of Advertising, 42, 1, pp. 162-170, (2023); Ante L., Wazinski F.P., Saggu A., Digital real estate in the metaverse: An empirical analysis of retail investor motivations, Finance Research Letters, 58, (2023); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Arruda H., Silva E.R., Lessa M., Proenca D., Bartholo R., VOSviewer and bibliometrix, Journal of the Medical Library Association, 110, 3, pp. 392-395, (2022); Baas J., Schotten M., Plume A., Cote G., Karimi R., Scopus as a curated, high-quality bibliometric data source for academic research in quantitative science studies, Quantitative Science Studies, 1, 1, pp. 377-386, (2020); Ball M., The metaverse: And how it will revolutionize everything, (2022); Bamel N., Kumar S., Bamel U., Lim W.M., Sureka R., The state of the art of innovation management: Insights from a retrospective review of the European Journal of Innovation Management, European Journal of Innovation Management, (2023); Basu R., Lim W.M., Kumar A., Kumar S., Marketing analytics: The bridge between customer psychology and marketing decision-making, Psychology & Marketing, 40, 12, pp. 2588-2611, (2023); Barrera K.G., Shah D., Marketing in the metaverse: Conceptual understanding, framework, and research agenda, Journal of Business Research, 155, (2023); Belk R., Humayun M., Brouard M., Money, possessions, and ownership in the Metaverse: NFTs, cryptocurrencies, web3 and wild markets, Journal of Business Research, 153, pp. 198-205, (2022); Bourlakis M., Papagiannidis S., Li F., Retail spatial evolution: Paving the way from traditional to metaverse retailing, Electronic Commerce Research, 9, pp. 135-148, (2009); Branca G., Resciniti R., Loureiro S.M.C., Virtual is so real! Consumers' evaluation of product packaging in virtual reality, Psychology & Marketing, 40, 3, pp. 596-609, (2023); Broadus R.N., Toward a definition of “bibliometrics”, Scientometrics, 12, pp. 373-379, (1987); Buchholz F., Oppermann L., Prinz W., There's more than one metaverse. i-com, 21, 3, pp. 313-324, (2022); Buhalis D., Lin M.S., Leung D., Metaverse as a driver for customer experience and value co-creation: Implications for hospitality and tourism management and marketing, International Journal of Contemporary Hospitality Management, 35, 2, pp. 701-716, (2022); Buhalis D., O'Connor P., Leung R., Smart hospitality: From smart cities and smart tourism towards agile business ecosystems in networked destinations, International Journal of Contemporary Hospitality Management, 35, 1, pp. 369-393, (2023); Caputo A., Kargina M., A user-friendly method to merge Scopus and Web of Science data during bibliometric analysis, Journal of Marketing Analytics, 10, 1, pp. 82-88, (2022); Chalmers D., Fisch C., Matthews R., Quinn W., Recker J., Beyond the bubble: Will NFTs and digital proof of ownership empower creative industry entrepreneurs?, Journal of Business Venturing Insights, 17, (2022); Chandra S., Verma S., Lim W.M., Kumar S., Donthu N., Personalization in personalized marketing: Trends and ways forward, Psychology & Marketing, 39, 8, pp. 1529-1562, (2022); Choi H.S., Kim S.H., A content service deployment plan for metaverse museum exhibitions—Centering on the combination of beacons and HMDs, International Journal of Information Management, 37, 1, pp. 1519-1527, (2017); Ciasullo M.V., Lim W.M., Digital transformation and business model innovation: Advances, challenges and opportunities, International Journal of Quality and Innovation, 6, 1, pp. 1-6, (2022); Damar M., Metaverse shape of your life for future: A bibliometric snapshot, Journal of Metaverse, 1, 1, pp. 1-8, (2021); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Donthu N., Lim W.M., Kumar S., Pandey N., Tribute to a marketing legend: Commemorating the contributions of Shelby D. Hunt with implications for the future of marketing, Journal of Business Research, 164, (2023); Duan H., Li J., Fan S., Lin Z., Wu X., (2021); Dwivedi Y.K., Hughes L., Baabdullah A.M., Ribeiro-Navarrete S., Giannakis M., Al-Debei M.M., Wamba S.F., Metaverse beyond the hype: Multidisciplinary perspectives on emerging challenges, opportunities, and agenda for research, practice and policy, International Journal of Information Management, 66, (2022); Dwivedi Y.K., Hughes L., Wang Y., Alalwan A.A., Ahn S.J., Balakrishnan J., Wirtz J., Metaverse marketing: How the metaverse will shape the future of consumer research and practice, Psychology & Marketing, 40, 4, pp. 750-776, (2023); Echchakoui S., Why and how to merge Scopus and Web of Science during bibliometric analysis: The case of sales force literature from 1912 to 2019, Journal of Marketing Analytics, 8, pp. 165-184, (2020); Falchuk B., Loeb S., Neff R., The social metaverse: Battle for privacy, IEEE Technology and Society Magazine, 37, 2, pp. 52-61, (2018); Far S.B., Rad A.I., Applying digital twins in metaverse: User interface, security and privacy challenges, Journal of Metaverse, 2, 1, pp. 8-15, (2022); Flavian C., Ibanez-Sanchez S., Orus C., The impact of virtual, augmented and mixed reality technologies on the customer experience, Journal of Business Research, 100, pp. 547-560, (2019); Gadalla E., Keeling K., Abosag I., Metaverse-retail service quality: A future framework for retail service quality in the 3D internet, Journal of Marketing Management, 29, 13-14, pp. 1493-1517, (2013); Ghosh I., Alfaro-Cortes E., Gamez M., Garcia N., Do travel uncertainty and invasion rhetoric spur Metaverse financial asset? – Gauging the role of media influence, Finance Research Letters, 51, (2023); Gupta B.B., Gaurav A., Albeshri A.A., Alsalman D., New paradigms of sustainable entrepreneurship in metaverse: A micro-level perspective, International Entrepreneurship and Management Journal, 19, pp. 1449-1465, (2023); Gursoy D., Malodia S., Dhir A., The metaverse in the hospitality and tourism industry: An overview of current trends and future research directions, Journal of Hospitality Marketing & Management, 31, 5, pp. 527-534, (2022); Hassani H., Huang X., MacFeely S., Enabling digital twins to support the UN SDGs, Big Data and Cognitive Computing, 6, 4, (2022); Hassouneh D., Brengman M., Retailing in social virtual worlds: Developing a typology of virtual store atmospherics, Journal of Electronic Commerce Research, 16, 3, pp. 218-241, (2015); Hemphill T.A., The ‘metaverse’ and the challenge of responsible standards development, Journal of Responsible Innovation, 10, 1, (2023); Hollensen S., Kotler P., Opresnik M.O., Metaverse – The new marketing universe, Journal of Business Strategy, 44, 3, pp. 119-125, (2023); Hosahally S., Zaremba A., A decision-making characteristics framework for marketing attribution in practice: Improving empirical procedures, Journal of Digital & Social Media Marketing, 11, 1, pp. 89-100, (2023); Hulland J., Bibliometric reviews—some guidelines, Journal of the Academy of Marketing Science, (2024); Joshi Y., Lim W.M., Jagani K., Kumar S., Social media influencer marketing: Foundations, trends, and ways forward, Electronic Commerce Research, (2024); Joy A., Zhu Y., Pena C., Brouard M., Digital future of luxury brands: Metaverse, digital fashion, and non-fungible tokens, Strategic Change, 31, 3, pp. 337-343, (2022); Kim J., Advertising in the metaverse: Research agenda, Journal of Interactive Advertising, 21, 3, pp. 141-144, (2021); Koohang A., Nord J.H., Ooi K.B., Tan G.W.H., Al-Emran M., Aw E.C.X., Wong L.W., Shaping the metaverse into reality: A holistic multidisciplinary understanding of opportunities, challenges, and avenues for future investigation, Journal of Computer Information Systems, 63, 3, pp. 735-765, (2023); Kozinets R.V., Immersive netnography: A novel method for service experience research in virtual reality, augmented reality and metaverse contexts, Journal of Service Management, 34, 1, pp. 100-125, (2022); Kraus S., Breier M., Lim W.M., Dabic M., Kumar S., Kanbach D., Ferreira J.J., Literature reviews as independent studies: Guidelines for academic practice, Review of Managerial Science, 16, 8, pp. 2577-2595, (2022); Kraus S., Kanbach D.K., Krysta P.M., Steinhoff M.M., Tomini N., Facebook and the creation of the metaverse: Radical business model innovation or incremental transformation?, International Journal of Entrepreneurial Behavior & Research, 28, 9, pp. 52-77, (2022); Kraus S., Kumar S., Lim W.M., Kaur J., Sharma A., Schiavone F., From moon landing to metaverse: Tracing the evolution of Technological Forecasting and Social Change, Technological Forecasting and Social Change, 189, (2023); Kumar S., Sahoo S., Lim W.M., Dana L.P., Religion as a social shaping force in entrepreneurship and business: Insights from a technology-empowered systematic literature review, Technological Forecasting and Social Change, 175, (2022); Kumar S., Sharma D., Rao S., Lim W.M., Mangla S.K., Past, present, and future of sustainable finance: Insights from big data analytics through machine learning of scholarly research, Annals of Operations Research, (2024); Kumar S., Sureka R., Lucey B.M., Dowling M., Vigne S., Lim W.M., MetaMoney: Exploring the intersection of financial systems and virtual worlds, Research in International Business and Finance, 68, (2024); Lal M., Kumar S., Pandey D.K., Rai V.K., Lim W.M., Exchange rate volatility and international trade, Journal of Business Research, 167, (2023); Lee C.T., Ho T.Y., Xie H.H., Building brand engagement in metaverse commerce: The role of branded non-fungible toekns (BNFTs), Electronic Commerce Research and Applications, 58, (2023); Lee L.H., Braud T., Zhou P., Wang L., Xu D., Lin Z., Hui P., All one needs to know about metaverse: A complete survey on technological singularity, virtual ecosystem, and research agenda, Journal of Latex Class Files, 14, 6, pp. 1-66, (2021); Lee S.G., Trimi S., Byun W.K., Kang M., Innovation and imitation effects in metaverse service adoption, Service Business, 5, pp. 155-172, (2011); Lim W.M., History, lessons, and ways forward from the COVID-19 pandemic, International Journal of Quality and Innovation, 5, 2, pp. 101-108, (2021); Lim W.M., Pro-active peer review for premier journals, Industrial Marketing Management, 95, pp. 65-69, (2021); Lim W.M., The art of writing for premier journals, Global Business and Organizational Excellence, 41, 6, pp. 5-10, (2022); Lim W.M., The art of revising for premier journals, Global Business and Organizational Excellence, 42, 1, pp. 5-9, (2022); Lim W.M., Philosophy of science and research paradigm for business research in the transformative age of automation, digitalization, hyperconnectivity, obligations, globalization, and sustainability, Journal of Trade Science, 11, 2-3, pp. 3-30, (2023); Lim W.M., Kumar S., Guidelines for interpreting the results of bibliometric analysis: A sensemaking approach, Global Business and Organizational Excellence, 43, 2, pp. 17-26, (2024); Lim W.M., Kumar S., Ali F., Advancing knowledge through literature reviews: ‘What’, ‘why’, and ‘how to contribute’, The Service Industries Journal, 42, 7-8, pp. 481-513, (2022); Lim W.M., Kumar S., Verma S., Chaturvedi R., Alexa, what do we know about conversational commerce? Insights from a systematic literature review, Psychology & Marketing, 39, 6, pp. 1129-1155, (2022); Lim W.M., Rasul T., Kumar S., Ala M., Past, present, and future of customer engagement, Journal of Business Research, 140, pp. 439-458, (2022); Lim W.M., Yap S.F., Makkar M., Home sharing in marketing and tourism at a tipping point: What do we know, how do we know, and where should we be heading?, Journal of Business Research, 122, pp. 534-566, (2021); Lumineau F., Wang W., Schilke O., Blockchain governance—A new way of organizing collaborations?, Organization Science, 32, 2, pp. 500-521, (2021); Mahajan R., Lim W.M., Sareen M., Kumar S., Panwar R., Stakeholder theory, Journal of Business Research, 166, (2023); Mamidala V., Kumari P., Investigating herding severity in different NFT categories, Finance Research Letters, 58, (2023); Miao F., Kozlenkova I.V., Wang H., Xie T., Palmatier R.W., An emerging theory of avatar marketing, Journal of Marketing, 86, 1, pp. 67-90, (2022); Moher D., Liberati A., Tetzlaff J., Altman D.G., PRISMA Group, Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement, Annals of Internal Medicine, 151, 4, pp. 264-269, (2009); Mukherjee D., Lim W.M., Kumar S., Donthu N., Guidelines for advancing theory and practice through bibliometric research, Journal of Business Research, 148, pp. 101-115, (2022); Mystakidis S., Metaverse. Encyclopedia, 2, 1, pp. 486-497, (2022); Nakavachara V., Saengchote K., Does unit of account affect willingness to pay? Evidence from metaverse LAND transactions, Finance Research Letters, 49, (2022); Page M., McKenzie J.E., Bossuyt P.M., Moher D., The PRISMA 2020 statement: AN updated guideline for reporting systematic reviews, Systematic Reviews, 10, (2021); Papagiannidis S., Bourlakis M., Li F., Making real money in virtual worlds: MMORPGs and emerging business opportunities, challenges and ethical implications in metaverses, Technological Forecasting and Social Change, 75, 5, pp. 610-622, (2008); Park S.M., Kim Y.G., A metaverse: Taxonomy, components, applications, and open challenges, IEEE Access, 10, pp. 4209-4251, (2022); Paul J., Lim W.M., O'Cass A., Hao A.W., Bresciani S., Scientific procedures and rationales for systematic literature reviews (SPAR-4-SLR), International Journal of Consumer Studies, 45, 4, pp. O1-O16, (2021); Polas M.R.H., Jahanshahi A.A., Kabir A.I., Sohel-Uz-Zaman A.S.M., Osman A.R., Karim R., Artificial intelligence, blockchain technology, and risk-taking behavior in the 4.0 IR Metaverse Era: Evidence from Bangladesh-based SMEs. Journal of Open, Innovation, 8, 3, (2022); Pritchard A., Statistical bibliography or bibliometrics?, Journal of Documentation, 25, 4, pp. 348-349, (1969); Qiao X., Zhu H., Tang Y., Peng C., Time-frequency extreme risk spillover network of cryptocurrency coins, DeFi tokens and NFTs, Finance Research Letters, 51, (2023); Richter S., Richter A., What is novel about the metaverse?, International Journal of Information Management, 73, (2023); Sharma W., Lim W.M., Kumar S., Verma A., Kumra R., Game on! A state-of-the-art overview of doing business with gamification, Technological Forecasting and Social Change, 198, (2024); Shen B., Tan W., Guo J., Zhao L., Qin P., How to promote user purchase in metaverse? A systematic literature review on consumer behavior research and virtual commerce application design, Applied Sciences, 11, 23, (2021); Simsek Z., Vaara E., Paruchuri S., Nadkarni S., Shaw J.D., New ways of seeing big data, Academy of Management Journal, 62, 4, pp. 971-978, (2019); Soon P.S., Lim W.M., Gaur S.S., The role of emotions in augmented reality, Psychology & Marketing, 40, 11, pp. 2387-2412, (2023); Stephenson N., Snowcrash, (1992); Steuer J., Defining virtual reality: Dimensions determining telepresence, Journal of Communication, 42, 4, pp. 73-93, (1992); Sung E., Kwon O., Sohn K., NFT luxury brand marketing in the metaverse: Leveraging blockchain-certified NFTs to drive consumer behavior, Psychology & Marketing, 40, 11, pp. 2306-2325, (2023); Tan T.M., Salo J., Ethical marketing in the blockchain-based sharing economy: Theoretical integration and guiding insights, Journal of Business Ethics, 183, 4, pp. 1113-1140, (2023); Tan T.M., Makkonen H., Kaur P., Salo J., How do ethical consumers utilize sharing economy platforms as part of their sustainable resale behavior? The role of consumers’ green consumption values, Technological Forecasting and Social Change, 176, (2022); Tlili A., Huang R., Kinshuk X., Metaverse for climbing the ladder toward ‘Industry 5.0’and ‘Society 5.0’?, The Service Industries Journal, 43, 3-4, pp. 260-287, (2023); Traag V.A., Waltman L., Van Eck N.J., From Louvain to Leiden: Guaranteeing well-connected communities, Scientific Reports, 9, 1, (2019); Truong V.T., Le L.B., Niyato D., Blockchain meets metaverse and digital asset management: A comprehensive survey, IEEE Access, 11, pp. 26258-26288, (2023); Van Eck N., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); (2023); von der Au S., Rauschnabel P.A., Felix R., Hinsch C., Context in augmented reality marketing: Does the place of use matter?, Psychology & Marketing, 40, 11, pp. 2447-2463, (2023); Wang Y., Su Z., Zhang N., Xing R., Liu D., Luan T.H., Shen X., A survey on metaverse: Fundamentals, security, and privacy, IEEE Communications Surveys & Tutorials, 25, 1, pp. 319-352, (2022); Wedel M., Bigne E., Zhang J., Virtual and augmented reality: Advancing research in consumer marketing, International Journal of Research in Marketing, 37, 3, pp. 443-465, (2020); Yang L., Recommendations for metaverse governance based on technical standards, Humanities and Social Sciences Communications, 10, 1, pp. 1-10, (2023); Yencha C., Spatial heterogeneity and non-fungible token sales: Evidence from Decentraland LAND sales, Finance Research Letters, 58, (2023); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","W.M. Lim; Dean's Office, Sunway Business School, Sunway University, Jalan Universiti, Selangor, Bandar Sunway, 47500, Malaysia; email: lim@wengmarc.com","","Elsevier Inc.","","","","","","01482963","","JBRED","","English","J. Bus. Res.","Article","Final","All Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-85196286855" -"Gahane V.; Deshpande Y.","Gahane, Varsha (59295100800); Deshpande, Yogesh (57202891781)","59295100800; 57202891781","Gynecological Cancer Research in India: A Bibliometric Analysis","2025","Indian Journal of Surgery","87","2","120522","253","266","13","1","10.1007/s12262-024-04132-8","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105003567840&doi=10.1007%2fs12262-024-04132-8&partnerID=40&md5=70c6e689950768793860e680b2bf86bd","Department of Humanities and Social Sciences, Visvesvaraya National Institute of Technology, Nagpur, 440010, India","Gahane V., Department of Humanities and Social Sciences, Visvesvaraya National Institute of Technology, Nagpur, 440010, India; Deshpande Y., Department of Humanities and Social Sciences, Visvesvaraya National Institute of Technology, Nagpur, 440010, India","Gynecological cancer originating in the female reproductive tract is one of the most common cancers among women, and its incidence is increasing every year in India. This results in high mortality, poor survival outcomes, and psychological effects. Several theoretical and empirical investigations examined gynecological cancer and its varied influences. However, no bibliometric attempts were performed to screen these publications to comprehend the most recent developments and trends in gynecological cancer research in India. Thus, this study aimed to examine the recent development of gynecological cancer research using bibliometric analysis of 3378 research articles collected from the Web of Science database from 2003 to 2022. The study used the Bibliometrix and VOSviewer software to inspect the performance and the science mapping analysis. The performance analysis findings indicate an increase in publication trends after 2008 in India. In scientific production, India collaborated with 116 countries worldwide. The most productive journal, author, and institution are Plos One, Rengaswamy Sankaranarayanan, and All India Institute of Medical Sciences, respectively. By using keywords, intellectual structure, and conceptual structure, the analysis indicates that future studies could focus on cervical carcinoma, ovarian cancer, human papillomavirus, and epithelial ovarian cancer. In light of the overall findings, it is recommended that academicians and practitioners interested in gynecological cancer-based research deliver an overview of the field by providing readers with essential papers, authors, universities, concepts, and sources. These outcomes will also help scholars in gaining a better understanding of current developments, trends, and issues in gynecological cancer research. © Association of Surgeons of India 2024.","Bibliometric analysis; Gynecological cancer; India; Performance analysis; Science mapping; Web of Science","","","","","","","","Cancer Today: Estimated Number of New Cases in 2020, Worldwide, Female, All Ages, (2021); Jones G.L., Kennedy S.H., The impact of treatment for gynecological cancer on health-related quality of life (HRQoL): A systematic review, Am J Obstet Gynecol, 194, 1 Electronic:, pp. 26-42, (2006); Di Tucci C., Galati G., Mattei G., Chine A., Fracassi A., Muzii L., Fertility after cancer: risks and successes, Cancers (Basel), 14, 10, (2022); Zhao J., Kong Y., Xiang Y., Yang J., The research landscape of the quality of life or psychological impact on gynecological cancer patients: a bibliometric analysis, Front Oncol, 13, (2023); Torre L.A., Bray F., Siegel R.L., Ferlay J., Lortet-Tieulent J., Jemal A., Global cancer statistics, 2012, CA: A Cancer J Clin, 65, 2, pp. 87-108, (2015); Crane K., Palliative care gains ground in developing countries, JNCI J National Cancer Inst, 102, 21, pp. 1613-1615, (2010); World Health Organisation (WHO) The Global Cancer Observatory(GLOBOCAN), Globocan, (2020); Secinaro S., Brescia V., Calandra D., Biancone P., Employing bibliometric analysis to identify suitable business models for electric cars, J Clean Prod, 1, 264, (2020); Ahmad S., Rehman S.U., Iqbal A., Farooq R.K., Shahid A., Ullah M.I., Breast cancer research in Pakistan: a bibliometric analysis, SAGE Open, 11, 3, (2021); Anaya-Ruiz M., Vincent A.K., Perez-Santos M., Cervical cancer trends in Mexico: incidence, mortality and research output, Asian Pac J Cancer Prev, 15, 20, pp. 8689-8692, (2014); El Bairi K., Al Jarroudi O., Afqir S., Tracing ovarian cancer research in Morocco: a bibliometric analysis, Gynecol Oncol Rep, 37, (2021); Huang Y., Chen P., Peng B., Liao R., Huang H., Huang M., Et al., The top 100 most cited articles on triple-negative breast cancer: a bibliometric analysis, Clin Exp Med, 23, 2, pp. 175-201, (2023); Zhang J., Zhu H., Wang J., Chen Y., Li Y., Chen X., Et al., Machine learning in non-small cell lung cancer radiotherapy: a bibliometric analysis, Front Oncol, 13, (2023); Mapping Trends and Hotspots regarding Clinical Research on COVID-19: A Bibliometric Analysis of Global Research - Pubmed; Pritchard A., Statistical bibliography or bibliometrics?, J Doc, 1, 25, pp. 348-349, (1969); Khanra S., Dhir A., Kaur P., Mantymaki M., Bibliometric analysis and literature review of ecotourism: toward sustainable development, Tour Manag Perspect, 1, 37, (2021); Tandon A., Kaur P., Mantymaki M., Dhir A., Blockchain applications in management: a bibliometric analysis and literature review, Technol Forecast Soc Chang, 1, 166, (2021); Zhang D., Zhang Z., Managi S., A bibliometric analysis on green finance: current status, development, and future directions, Financ Res Lett, 1, 29, pp. 425-430, (2019); Liu J., Li X., Wang S., What have we learnt from 10 years of fintech research? A scientometric analysis, Technological Forecasting and Social Change [Internet], 155, C, (2020); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, J Bus Res, 1, 133, pp. 285-296, (2021); Xue X., Wang L., Yang R.J., Exploring the science of resilience: critical review and bibliometric analysis, Nat Hazards, 90, 1, pp. 477-510, (2018); Gyanendra Y., Yumnam G., Alam W., Singh C., A bibliometric analysis and assessment of scientific studies trend on groundwater research in India during 1989–2020, Arab J Geosci, 15, 16, (2022); Mukherjee D., Kumar S., Mukherjee D., Goyal K., Mapping five decades of international business and management research on India: a bibliometric analysis and future directions, J Bus Res, 1, 145, pp. 864-891, (2022); Vr N., Patil S.B., Indian publications on SARS-CoV-2: a bibliometric study of WHO COVID-19 database, Diabetes Metab Syndr Clin Res Rev, 14, 5, pp. 1171-1178, (2020); Nayak S., Behera D.K., Shetty J., Shetty A., Kumar S., Shenoy S.S., Bibliometric analysis of scientific publications on health care insurance in India from 2000 to 2021, Int J Healthcare Manag, 16, 2, pp. 188-196, (2023); Panes P., Macariola M.A., Niervo C., Maghanoy A.G., Garcia K.P., Ignacio J.J., A bibliometric approach for analyzing the potential role of waste-derived nanoparticles in the upstream oil and gas industry, Clean Eng Technol, 1, 8, (2022); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, J Informet, 11, 4, pp. 959-975, (2017); Yang Z., Lin M., Li Y., Zhou W., Xu B., Assessment and selection of smart agriculture solutions using an information error-based Pythagorean fuzzy cloud algorithm, Int J Intell Syst, 36, 11, pp. 6387-6418, (2021); Chen X., Liu Y., Visualization analysis of high-speed railway research based on CiteSpace, Transp Policy, 1, 85, pp. 1-17, (2020); Cella D., Rose P., Wenzel L., Monk B., Huang H., Clinically meaningful quality-of-life changes in ovarian cancer: Results from gynecologic oncology group clinical trial 152, Clinical Therapeutics [Internet], 25, (2003); van Eck N.J., Waltman L., Vosviewer Manual, (2020); Bretas V.P.G., Alon I., Franchising research on emerging markets: bibliometric and content analyses, J Bus Res, 133, C, pp. 51-65, (2021); Forliano C., De Bernardi P., Yahiaoui D., Entrepreneurial universities: a bibliometric analysis within the business and management domains, Technol Forecast Soc Chang, 1, 165, (2021); Hirsch J.E., Does the h index have predictive power?, Proc Natl Acad Sci, 104, 49, pp. 19193-19198, (2007); Shoaib M., Zhang S., Ali H., A bibliometric study on blockchain-based supply chain: a theme analysis, adopted methodologies, and future research agenda, Environ Sci Pollut Res, 30, 6, pp. 14029-14049, (2023); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: a practical application to the Fuzzy Sets Theory field, J Informet, 5, 1, pp. 146-166, (2011); Elango B., A Bibliometric analysis of franchising research (1988–2017), J Entrep, 28, 2, pp. 223-249, (2019); Freeman L.C., Centrality in social networks conceptual clarification, Social Networks, 1, 3, pp. 215-239, (1978); Huang Y., Liu H., Pan J., Identification of data mining research frontier based on conference papers, Int Jo Crowd Sci, 5, 2, pp. 143-153, (2021); Kang Q., Li H., Cheng Y., Kraus S., Entrepreneurial ecosystems: analyzing the status quo, Knowl Manag Res Pract, 1, 16, pp. 8-20, (2021); Koseoglu M.A., Growth and structure of authorship and co-authorship network in the strategic management realm: evidence from the Strategic Management Journal, BRQ Bus Res Q, 19, 3, pp. 153-170, (2016); Wang N., Liang H., Jia Y., Ge S., Xue Y., Wang Z., Cloud computing research in the IS discipline: a citation/co-citation analysis, Decis Support Syst, 1, 86, pp. 35-47, (2016)","V. Gahane; Department of Humanities and Social Sciences, Visvesvaraya National Institute of Technology, Nagpur, 440010, India; email: varshagahane02@gmail.com","","Springer","","","","","","09722068","","IJSUA","","English","Indian J. Surg.","Review","Final","","Scopus","2-s2.0-105003567840" -"Al Rousan R.; Khasawneh N.; Sujood","Al Rousan, Ramzi (57734508000); Khasawneh, Nermin (23501912900); Sujood (57237193200)","57734508000; 23501912900; 57237193200","Mapping 30 years of tourism and hospitality research in the Arab world: a review based on bibliometric analysis","2024","Tourism Review","79","6","","1280","1298","18","2","10.1108/TR-04-2023-0201","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175691069&doi=10.1108%2fTR-04-2023-0201&partnerID=40&md5=11db19c5b56436a1b48ed56e9dee70d4","Department of Sustainable Tourism, Faculty of Tourism and Heritage, The Hashemite University, Queen Rania, Zarqa, Jordan; Department of Sustainable Tourism, Faculty of Tourism and Heritage, Queen Rania, Zarqa, Jordan; Department of Tourism and Hospitality Management, Jamia Millia Islamia Central University, New Delhi, India","Al Rousan R., Department of Sustainable Tourism, Faculty of Tourism and Heritage, The Hashemite University, Queen Rania, Zarqa, Jordan; Khasawneh N., Department of Sustainable Tourism, Faculty of Tourism and Heritage, Queen Rania, Zarqa, Jordan; Sujood, Department of Tourism and Hospitality Management, Jamia Millia Islamia Central University, New Delhi, India","Purpose: The Arab world has witnessed a remarkable surge in the growth of its tourism and hospitality (T&H) industry, positioning it as a vital cornerstone for sustainable development. However, an exclusive bibliometric analysis of T&H research contributed by the Arab world has not yet been conducted in the past 30 years, that is, 1993–2022. Therefore, the purpose of this study is to provide a first-of-its-kind bibliometric assessment and visualization of T&H research produced by the Arab world spanning from 1993 to 2022. Design/methodology/approach: A comprehensive collection of 1,327 scientific publications related to T&H research contributed by the Arab world was acquired from the Web of Science Core Collection database. To perform a large-scale bibliometric analysis, encompassing performance analysis, science mapping and network analysis, this study used state-of-the-art analytical tools, namely, Bibliometrix package of R Studio and VOSviewer. Findings: The findings of this study show that the Arab world’s research on T&H has significantly surged since COVID-19, contributing nearly half (50.56%) of the total literature in the T&H domain between 2020 and 2022. Elshaer IA (Suez Canal University, Egypt) emerged as the most productive author, while Nusair K (Sultan Qaboos University, Oman) was identified as the most impactful author in the T&H domain in the Arab world. The most productive journal was found to be Sustainability (MDPI), while Tourism Management (Elsevier) was identified as the most impactful journal in the field of T&H. Furthermore, the thematic analysis highlights that research themes in T&H are not static but rather constantly evolving in response to dynamic changes in the industry, such as emerging trends, shifts in tourist preferences and the impact of global events like the COVID-19 pandemic. Originality/value: To the best of the authors’ knowledge, this is the first bibliometric analysis of T&H research contributed by the Arab world, specifically covering the period from 1993 to 2022. This study's findings can inform the development of strategies and policies for the sustainable and competitive growth of the T&H industry in the Arab world. This study highlights the importance of continued research and collaboration among industry professionals, academics and policymakers to promote innovation and drive positive change in the T&H sector in the Arab world. © 2023, Emerald Publishing Limited.","Arab world; Bibliometric analysis; Hospitality; Keywords analysis; Network analysis; Thematic analysis; Tourism","","","","","","","","Algassim A.A., Abuelhassan A.E., The effect of COVID-19 on potential tourist's consumption behavior: evidence from GCC countries, Journal of Association of Arab Universities for Tourism and Hospitality, 20, 1, pp. 129-144, (2021); Almuhrzi H., Alriyami H., Scott N., Tourism in the Arab World: An Industry Perspective, (2017); Alsharari N.M., Internationalisation of the higher education system: an interpretive analysis, International Journal of Educational Management, 32, 3, pp. 359-381, (2018); Bhutia P.D., Saudi Arabia’s tourism boosts Post-Covid recovery of real estate sector, (2023); Correia A., Kozak M., Past, present and future: trends in tourism research, Current Issues in Tourism, 25, 6, pp. 995-1010, (2022); Das A., Kondasani R.K.R., Deb R., Religious tourism: a bibliometric and network analysis, Tourism Review, (2023); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Dwivedi Y.K., Shareef M.A., Akram M.S., Malik F.T., Kumar V., Giannakis M., An Attitude-Behavioral model to understand people’s behavior towards tourism during COVID-19 pandemic, Journal of Business Research, 161, (2023); Fusco F., Marsilio M., Guglielmetti C., Co-production in health policy and management: a comprehensive bibliometric review, BMC Health Services Research, 20, 1, (2020); Gaviria-Marin M., Merigo J.M., Baier-Fuentes H., Knowledge management: a global examination based on bibliometric analysis, Technological Forecasting and Social Change, 140, pp. 194-220, (2019); Hernandez J.B., Chalela S., Arias J.V., Arias A.V., Research trends in the study of ICT based learning communities: a bibliometric analysis, EURASIA Journal of Mathematics, Science and Technology Education, 13, 5, pp. 1539-1562, (2017); Isik C., Aydin E., Dogru T., Rehman A., Sirakaya-Turk E., Karagoz D., Innovation research in tourism and hospitality field: a bibliometric and visualisation analysis, Sustainability, 14, 13, (2022); Klingmann A., Rescripting Riyadh: how the capital of Saudi Arabia employs urban megaprojects as catalysts to enhance the quality of life within the city’s neighborhoods, Journal of Place Management and Development, 16, 1, pp. 45-72, (2023); Knani M., Echchakoui S., Ladhari R., Artificial intelligence in tourism and hospitality: bibliometric analysis and research agenda, International Journal of Hospitality Management, 107, (2022); Lew A.A., Cheer J.M., Haywood M., Brouder P., Salazar N.B., Visions of travel and tourism after the global COVID-19 transformation of 2020, Tourism Geographies, 22, 3, pp. 455-466, (2020); Liao H., Yang S., Kazimieras Zavadskas E., Skare M., An overview of fuzzy multi-criteria decision-making methods in hospitality and tourism industries: bibliometrics, methodologies, applications and future directions, Economic Research-Ekonomska Istraživanja, 36, 3, (2022); Lima Santos L., Cardoso L., Araujo-Vila N., Fraiz-Brea J.A., Sustainability perceptions in tourism and hospitality: a mixed-method bibliometric approach, Sustainability, 12, 21, (2020); Mauleon-Mendez E., Genovart-Balaguer J., Martorell-Cunill O., Mulet-Forteza C., Tourism research: a bibliometric and country analysis, Journal of Intelligent & Fuzzy Systems, 38, 5, pp. 5565-5577, (2020); Menon D., Gunasekar S., Dixit S.K., Das P., Mandal S., Present and prospective research themes for tourism and hospitality education post-COVID19: a bibliometric analysis, Journal of Hospitality, Leisure, Sport & Tourism Education, 30, (2022); Muritala B.A., Sanchez-Rebull M.V., Hernandez-Lara A.B., A bibliometric analysis of online reviews research in tourism and hospitality, Sustainability, 12, 23, (2020); Naseem S., The role of tourism in economic growth: empirical evidence from Saudi Arabia, Economies, 9, 3, (2021); Nusair K., Butt I., Nikhashemi S.R., A bibliometric analysis of social media in hospitality and tourism research, International Journal of Contemporary Hospitality Management, 31, 7, pp. 2691-2719, (2019); Okumus B., Koseoglu M.A., Ma F., Food and gastronomy research in tourism and hospitality: a bibliometric analysis, International Journal of Hospitality Management, 73, pp. 64-74, (2018); Ozguzel S., Evaluation and identification of barriers to tourism in Islamic countries, Journal of Social Sciences and Humanities Research, 8, 3, pp. 61-68, (2020); Ratten V., COVID-19 and entrepreneurship: future research directions, Strategic Change, 30, 2, pp. 91-98, (2021); Shekhar S., Gupta A., Valeri M., Mapping research on family business in tourism and hospitality: a bibliometric analysis, Journal of Family Business Management, 12, 3, pp. 367-392, (2022); Shin H.H., Shin S., Gim J., Looking back three decades of hospitality and tourism technology research: a bibliometric approach, International Journal of Contemporary Hospitality Management, 35, 2, pp. 563-588, (2023); Skirka H., Middle east tourism predicted to return to pre-pandemic levels in 2023, (2023); Syed A., Saudi Arabia driving post-pandemic recovery of global tourism sector, (2022); Tabash M.I., Farooq U., El Refae G.A., Al-Faryan M.A.S., Athamena B., Impact of religious tourism on the economic development, energy consumption and environmental degradation: evidence from the kingdom of Saudi Arabia, Tourism Review, 78, 3, pp. 1004-1018, (2023); Vatankhah S., Darvishmotevali M., Rahimi R., Jamali S.M., Ale Ebrahim N., Assessing the application of multi-criteria decision making techniques in hospitality and tourism research: a bibliometric study, International Journal of Contemporary Hospitality Management, 35, 7, pp. 2590-2623, (2023); Wagner C.S., Whetsell T.A., Leydesdorff L., Growth of international collaboration in science: revisiting six specialties, Scientometrics, 110, 3, pp. 1633-1652, (2017); Global economic impact trends, WTTC, (2022); Middle east travel & tourism sector expected to create 3.6 million new jobs within the next decade, (2022)","Sujood; Department of Tourism and Hospitality Management, Jamia Millia Islamia Central University, New Delhi, India; email: sjdkhancool@gmail.com","","Emerald Publishing","","","","","","16605373","","","","English","Tour. Rev.","Review","Final","","Scopus","2-s2.0-85175691069" -"Pérez-Morón J.M.; García Alonso R.; Thoene U.","Pérez-Morón, James Manuel (57322375300); García Alonso, Roberto (57215572817); Thoene, Ulf (56766193900)","57322375300; 57215572817; 56766193900","Looking back to move forward: shedding light on the dark side of entrepreneurship","2024","New England Journal of Entrepreneurship","27","2","","152","172","20","5","10.1108/NEJE-10-2023-0088","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201694426&doi=10.1108%2fNEJE-10-2023-0088&partnerID=40&md5=44ce771cc7adfeb495cba06585f3e978","Universidad de La Sabana, Chía, Colombia; Universidad Tecnológica de Bolívar, Cartagena De Indias, Colombia; Universidad de Salamanca, Salamanca, Spain","Pérez-Morón J.M., Universidad de La Sabana, Chía, Colombia, Universidad Tecnológica de Bolívar, Cartagena De Indias, Colombia; García Alonso R., Universidad de La Sabana, Chía, Colombia, Universidad de Salamanca, Salamanca, Spain; Thoene U., Universidad de La Sabana, Chía, Colombia","Purpose: While entrepreneurship has long been heralded for its positive contributions, there is a growing recognition of its “dark side,” characterized by unproductive, unethical and destructive actions. This exploratory literature review aims to illuminate the underexplored dark side of entrepreneurship, thereby enriching the discourse on entrepreneurship’s dual nature. Design/methodology/approach: This study employs a robust mixed-method approach, integrating phenomenologically detailed co-citation bibliographic coupling with detailed thematic data and code-weaving. Science mapping tools like R-Bibliometrix and VOSviewer enhance the credibility of the findings by providing a sophisticated and reproducible methodological framework. Findings: This review defines dark entrepreneurship, its characteristics, and its complexities. We introduced the “Dark Entrepreneurship Trinity”: Ethical Complexity, Institutional Navigation and Conflict Entrepreneurialship, with Institutional Navigation as the apex theme. It elucidates how this theme influences ethical dilemmas and operational strategies in conflict zones, illustrated through a diagram depicting their complex interrelations and dynamics. Originality/value: The originality of this literature review lies in its comprehensive synthesis of the dark side of entrepreneurship. This review significantly contributes to the academic discourse by delineating a clearer picture of the destructive potentials of entrepreneurship. It compiles existing research, critically addresses the gaps and suggests future pathways for empirical studies. © 2024, James Manuel Pérez-Morón, Roberto García Alonso and Ulf Thoene.","Dark entrepreneurship; Destructive entrepreneurship; Entrepreneurship; Literature review","","","","","","European Unión NextGenerationEU; Universidad de La Sabana; Ministério da Ciência, Tecnologia e Inovação, MCTI, (909-2021); PRTR, (MCIN/AEI/10.13039/501100011033)","Funding text 1: All the authors have contributed equally and substantially to this article\u2019s research, analysis, and composition. Funding: We gratefully acknowledge the financial support received from the Colombian Ministry of Science, Technology, and Innovation (No. 909-2021), the Doctoral Program in Management of Organizations at the International School of Economic and Administrative Sciences, Universidad de La Sabana, Colombia, and support received as part of the research project (No.EICEA-85-2014). This support was instrumental in facilitating our research. The work of Roberto Garc\u00EDa Alonso was supported by the Grant Ayudas Mar\u00EDa Zambrano para la atracci\u00F3n de talento internacional funded by \u201CEuropean Uni\u00F3n NextGenerationEU/PRTR\u201D (No. MCIN/AEI/10.13039/501100011033). Competing interests: All authors of this article declare no competing interests.; Funding text 2: Funding: We gratefully acknowledge the financial support received from the Colombian Ministry of Science, Technology, and Innovation (No. 909-2021), the Doctoral Program in Management of Organizations at the International School of Economic and Administrative Sciences, Universidad de La Sabana, Colombia, and support received as part of the research project (No.EICEA-85-2014). This support was instrumental in facilitating our research. The work of Roberto Garc\u00EDa Alonso was supported by the Grant Ayudas Mar\u00EDa Zambrano para la atracci\u00F3n de talento internacional funded by \u201CEuropean Uni\u00F3n NextGenerationEU/PRTR\u201D (No. MCIN/AEI/10.13039/501100011033). 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Entrep.","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85201694426" -"DA SILVA M.J.N.; DA COSTA C.M.M.","DA SILVA, Maria José Nunes (58313132600); DA COSTA, Carlos Manuel Martins (59249720900)","58313132600; 59249720900","Crisis Leadership in Tourism and Hospitality: a science mapping analysis and PRISMA protocol","2025","Journal of Tourism and Development","48","","","478","524","46","0","10.34624/rtd.v48i0.37117","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105006804207&doi=10.34624%2frtd.v48i0.37117&partnerID=40&md5=789805ce053e23bdd26c0647627dc2d4","University of Aveiro, University of Évora, Portugal; University of Aveiro, Portugal","DA SILVA M.J.N., University of Aveiro, University of Évora, Portugal; DA COSTA C.M.M., University of Aveiro, Portugal","The volatile nature of 21st century tourism underscores the urgent need for immediate and effective crisis leadership. Given tourism's susceptibility to crises, from natural disasters to geopolitical conflicts, this topic is paramount for ensuring resilience and growth. This study aims to identify prevailing themes, authors, trends, and knowledge gaps and enrich the understanding of crisis leadership and crisis management differences, offering valuable insights into future research. “What are the prevailing themes, challenges, and future directions in tourism crisis leadership?” is the research question. The study delves into a science mapping analysis utilising the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) protocol to map the existing literature on tourism crisis leadership. A bibliometric analysis employing R Studio and Bibliometrix software facilitates a rigorous assessment of publication trends, networks and evolution, ensuring a reliable research process. Findings reveal a scarce literature landscape and a notable gap in the knowledge of tourism crisis leadership. This study underscores the need for crisis leadership in the complementarity of crisis management and highlights the increasing severity, frequency, and global effects of crises. It strongly advocates future research focusing on several players. Despite limitations, the study offers valuable insights for academia and the sector. © 2025, Universidade de Aveiro. All rights reserved.","crisis; crisis leadership; crisis management; PRISMA; tourism and hospitality","","","","","","","","Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Baker D., The effects of terrorism on the travel and tourism industry, International Journal of Religious Tourism and Pilgrimage, 2, 1, pp. 58-67, (2014); Bao Y., Tao of Crisis Management, (2011); Bennis W., Nanus B., Leaders, the strategies for taking charge, (1985); Benson A. M., Blackman D., To distribute leadership or not? 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Dev.","Article","Final","","Scopus","2-s2.0-105006804207" -"Mohammed J.N.; Okaiyeto K.; Haruna S.; Wan Dagang W.R.Z.; Oguntibeju O.O.; Ekundayo T.C.","Mohammed, Jibrin Ndejiko (57208866027); Okaiyeto, Kunle (55891426200); Haruna, Saidu (59812511300); Wan Dagang, Wan Rosmiza Zana (56218256900); Oguntibeju, Oluwafemi O. (9270093600); Ekundayo, Temitope Cyrus (57204841448)","57208866027; 55891426200; 59812511300; 56218256900; 9270093600; 57204841448","Systematic assessment on the remediation of Bisphenol A in the global environments: a mixed method analysis of research outputs","2024","Discover Environment","2","1","15","","","","4","10.1007/s44274-024-00045-1","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105004681161&doi=10.1007%2fs44274-024-00045-1&partnerID=40&md5=37ba7ef30c49a4e245cf2c4b5cc0cab5","Department of Microbiology, Faculty of Natural Sciences, Ibrahim Badamasi Babangida University, P M B 11, Niger, Lapai, Nigeria; Phytomedicine and Phytochemistry Group, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, 7536, South Africa; Department of Biological Sciences, Gombe State University, Gombe, Nigeria; Faculty of Science, Universiti Teknologi Malaysia, Johor, Johor Bahru, 81310, Malaysia; Department of Biological Sciences, University of Medical Sciences, Ondo, Ondo, Nigeria","Mohammed J.N., Department of Microbiology, Faculty of Natural Sciences, Ibrahim Badamasi Babangida University, P M B 11, Niger, Lapai, Nigeria; Okaiyeto K., Phytomedicine and Phytochemistry Group, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, 7536, South Africa; Haruna S., Department of Biological Sciences, Gombe State University, Gombe, Nigeria; Wan Dagang W.R.Z., Faculty of Science, Universiti Teknologi Malaysia, Johor, Johor Bahru, 81310, Malaysia; Oguntibeju O.O., Phytomedicine and Phytochemistry Group, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, 7536, South Africa; Ekundayo T.C., Department of Biological Sciences, University of Medical Sciences, Ondo, Ondo, Nigeria","Bisphenol A (BPA) is an endocrine-disrupting compound and a mutagenic agent that poses health hazards to living organisms, making it a global contaminant. Several remediation techniques have been reported in the literature, however, a mixed-method science mapping analysis of research trends on BPA is still lacking. The present study aimed to investigate global research trends in BPA remediation. Published research papers on BPA remediation indexed in Web of Science, PubMed, and Scopus between 1992 and 2021 were analysed qualitatively and quantitatively using science mapping algorithms including Rstudio, bibliometrix package and R Version 4.2.1. The thematic areas were determined using k-means clustering of the author-keywords while Porter’s stemming algorithm was used to stemmed inflectional terms to their roots. Overall, 640 documents were published by 1903 authors with 2.07 authors/article and 0.336 article/author, 4.31 co-authors/article, an annual growth rate of 17.35% and a collaboration index of 2.99. Research productivity increased from 1 article in 1992 to 93 articles in 2021. The citations of the topmost 23 articles ranged from 365 to 109 and the total citation per year ranged from 45.6 to 27.3. China (n = 267, 41.7%), Japan (n = 53, 8.3%), USA (n = 33, 5.2%) and Korea (n = 28, 4.4%) were respectively the top four countries based on the total of published articles and overall citation. There were 48 relevant keywords dominated by Bisphenol A, adsorption, biodegradation, and peroximonosulphate. The present analysis identifies research accomplishment, focus and gaps on Bisphenol A remediation and offer the researchers the information needed to forecast future research priorities that can help policymakers and governments to internationalize collaborations and create research curricula that can remediate BPA on a global scale. © The Author(s) 2024.","Bibliometric; Bisphenol A; Remediation; Research collaboration","","","","","","","","Shafei A., Matbouly M., Mostafa E., Al Sannat S., Abdelrahman M., Lewis B., Muhammad B., Shaima M., Mostafa R.M., Stop eating plastic, molecular signaling of bisphenol A in breast cancer, Environ Sci Pollut Res, 25, 24, pp. 23624-23630, (2018); Michalowicz J., Bisphenol A–sources, toxicity and biotransformation, Environ Toxicol Pharmacol, 37, 2, pp. 738-758, (2014); Bautista-Toledo I., Ferro-Garcia M., Rivera-Utrilla J., Moreno-Castilla C., Vegas Fernandez F., Bisphenol A removal from water by activated carbon. 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Chailurkit L., Aekplakorn W., Ongphiphadhanakul B., The association of serum bisphenol A with thyroid autoimmunity, Int J Environ Res Public Health, 13, 11, (2016); Conti I., Simioni C., Varano G., Brenna C., Costanzi E., Neri L.M., Legislation to limit the environmental plastic and microplastic pollution and their influence on human exposure, Environ Pollut, 288, (2021); Tian L., Goodyer C.G., Zheng J., Bayen S., Thermal degradation of bisphenol A and bisphenol S in water and fish (cod and basa) fillets, Food Chem, 328, (2020); Tarafdar A., Sirohi R., Balakumaran P.A., Reshmy R., Madhavan A., Sindhu R., Binod P., Kumar Y., Kumar D., Sim S.J., The hazardous threat of Bisphenol A: Toxicity, detection and remediation, J Hazard Mater, 423, (2022); Mansas C., Mendret J., BrosillonA S., Ayral A., Coupling catalytic ozonation and membrane separation: a review, Sep Purif Technol, 236, (2020); Chen Z.-H., Liu Z., Hu J.-Q., Cai Q.-W., Li X.-Y., Wang W., Faraj Y., Ju X.-J., Xie R., Chu L.-Y., β-Cyclodextrin-modified graphene oxide membranes with large adsorption capacity and high flux for efficient removal of bisphenol A from water, J Membr Sci, 595, (2020); Sun Z., Zhao L., Liu C., ZhenJ Y., Ma J., Fast adsorption of BPA with high capacity based on π-π electron donor-acceptor and hydrophobicity mechanism using an in-situ sp2 C dominant N-doped carbon, Chem Eng J, 381, (2020); Zhong X., Lu Z., Liang W., Hu B., The magnetic covalent organic framework as a platform for high-performance extraction of Cr (VI) and bisphenol a from aqueous solution, J Hazard Mater, 393, (2020); Babaei H., Nejad Z.G., Yaghmaei S., Farhadi F., Co-immobilization of multi-enzyme cascade system into the metal–organic frameworks for the removal of Bisphenol A, Chem Eng J, 461, (2023); Li A., Zhuang T., Shi W., Liang Y., Liao C., SongJiang M.G., Serum concentration of bisphenol analogues in pregnant women in China, Sci Total Environ, 707, (2020); Oguzie K.L., Qiao M., Zhao X., Oguzie E.E., Njoku V.O., Obodo G.A., Oxidative degradation of Bisphenol A in aqueous solution using cobalt ion-activated peroxymonosulfate, J Mol Liq, 313, (2020); Gan L., Fang X., Xu L., Wang L., Wu Y., Dai B., He W., Shi J., Boosted activity of δ-MnO2 by Kenaf derived carbon fiber for high-efficient oxidative degradation of bisphenol A in water, Mater Design, 203, (2021); Zorzo C.F., Inticher J.J., Borba F.H., Cabrera L.C., Dugatto J.S., Baroni S., Kreutz G.K., Seibert D., Bergamasco R., Oxidative degradation and mineralization of the endocrine disrupting chemical bisphenol-A by an eco-friendly system based on UV-solar/H2O2 with reduction of genotoxicity and cytotoxicity levels, Sci Total Environ, 770, (2021); Wang G., Dai J., Luo Q., Deng N., Photocatalytic degradation of bisphenol A by TiO2@ aspartic acid-β-cyclodextrin@ reduced graphene oxide, Sep Purif Technol, 254, (2021)","J.N. Mohammed; Department of Microbiology, Faculty of Natural Sciences, Ibrahim Badamasi Babangida University, Lapai, P M B 11, Niger, Nigeria; email: ndejiko@ibbu.edu.ng","","Springer Nature","","","","","","27319431","","","","English","Discov. Environ.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-105004681161" -"Greenal S.; Anilkumar S.","Greenal, Sherin (59187260800); Anilkumar, Shyni (57221685680)","59187260800; 57221685680","Development of decision support tools for post-disaster infrastructure reconstruction and recovery: a scoping study","2025","Sustainable and Resilient Infrastructure","10","2","","119","135","16","3","10.1080/23789689.2024.2365502","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105001479071&doi=10.1080%2f23789689.2024.2365502&partnerID=40&md5=0a9b2ca1f59b48ff234f167e522bf741","Department of Architecture and Planning, National Institute of Calicut, Kozhikode, India","Greenal S., Department of Architecture and Planning, National Institute of Calicut, Kozhikode, India; Anilkumar S., Department of Architecture and Planning, National Institute of Calicut, Kozhikode, India","A structured decision support system is imperative for guiding implementation of the dynamic and complex Post-disaster infrastructure reconstruction (PDIR) projects. This study attempts to appraise the scientific trend in the development decision support tools (DSTs) for PDIR during the last two decades and scope for future research. A detailed content analysis of literature extracted from online databases is performed to comprehend their objectives, methodologies along with typology and structure of DSTs. An objective analysis of research trend is performed using comprehensive science-mapping tool, ‘Bibliometrix’, followed by synthesizing the adaptability of DSTs in the present context.The scoping study has comprehended the scientific trends on developing DSTs as well as various approaches, methods and tools adopted in the field. The findings also deciphered the emerging research themes corroborating the need to develop better DSTs. The study recognizes potential research gaps in the development of DSTs globally and suggests future research directions. © 2024 Informa UK Limited, trading as Taylor & Francis Group.","Bibliometrix; comprehensive science-mapping; Decision support tool; post-disaster infrastructure reconstruction; project management","Artificial intelligence; Decision making; Decision support systems; Disasters; Project management; Bibliometrix; Comprehensive science-mapping; Decision support tool; Decision supports; Infrastructure reconstruction; Post disasters; Post-disaster infrastructure reconstruction; Reconstruction projects; Scoping; Support tool; Mapping","","","","","","","Afkhamiaghda M., Elwakil E., Machine learning-based FEMA Transitional Shelter Assistance (TSA) eligibility prediction models, Journal of Emergency Management (Weston, Mass), (2021); Alberto-Hernandez Y., Recovery process of the water distribution system after a seismic event, Sustainable Civil Infrastructures, (2019); Ali A., Ramakrishnan S., Faisal F., Akram T., Salam S., Ur Rahman S., Bibliometric analysis of finance and natural resources: Past trend, current development, and future prospects, Environment, Development and Sustainability, 25, 11, pp. 13035-13064, (2022); Arab A., Khodaei A., Han Z., Khator S.K., Proactive recovery of electric power assets for resiliency enhancement, Institute of Electrical and Electronics Engineers Access, 3, pp. 99-109, (2015); Barraque B., Moatty A., Haris M., Cheema A.R., Subasinghe C., Inzulza-Contardo J., Gatica-Araya P., Why Lessons Learnt Are Lost: Understanding the Complexity of Barriers to Build Back Better in Pakistan, Natural Hazards, 1, 3, pp. 285-300, (2017); Bellagamba X., Bradley B.A., Wotherspoon L.M., Lagrava W.D., A decision-support algorithm for post-earthquake water services recovery and its application to the 22 February 2011 mw 6.2 Christchurch earthquake, Earthquake Spectra, 35, 3, pp. 1397-1420, (2019); Bilau Abdulquadri A., Witt E., An analysis of issues for the management of post-disaster housing reconstruction, International Journal of Strategic Property Management, 20, 3, pp. 265-276, (2016); Chang Y., Wilkinson S., Potangaroa R., Seville E., Resourcing challenges for post-disaster housing reconstruction: A comparative analysis, Building Research and Information, 38, 3, pp. 247-264, (2010); Chang Y., Wilkinson S., Potangaroa R., Seville E., Identifying factors affecting resource availability for post-disaster reconstruction: A case study in China, Construction Management & Economics, 29, 1, pp. 37-48, (2011); Chester M.V., El Asmar M., Hayes S., Desha C., Post-disaster infrastructure delivery for resilience, Sustainability (Switzerland), 13, (2021); Chigbu U.E., Olusegun Atiku S., Du Plessis C.C., The science of literature reviews: Searching, identifying, selecting, and synthesising, Publications, 11, 1, (2023); Dervis H., Bibliometric analysis using Bibliometrix an R package, Journal of Scientometric Research, 8, 3, pp. 156-160, (2019); Deshmukh A., Hastak M., Enhancing community resilience: Optimal capacity building for expediting post disaster recovery, Proceedings of the 5th International Disaster and Risk Conference: Integrative Risk Management, IDRC Davos, pp. 302-305, (2014); Deshmukh A., Oh E.H., Hastak M., Impact of flood damaged critical infrastructure on communities and industries, Built Environment Project and Asset Management, 1, 2, pp. 156-175, (2011); 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Liu M., Scheepbouwer E., Giovinazzi S., Critical success factors for post-disaster infrastructure recovery: Learning from the Canterbury (NZ) earthquake recovery, Disaster Prevention and Management, 25, 5, pp. 685-700, (2016); Macaskill K., Guthrie P., Funding mechanisms for disaster recovery: Can we afford to build back better?, Procedia Engineering, 212, pp. 451-458, (2018); Minhas M.R., Potdar V., Decision support systems in construction: A bibliometric analysis, Buildings, 10, 6, (2020); Mitchell J.K., Resilient disaster recovery: The role of health impact assessment, Urban Book Series, (2018); Mohammadnazari Z., Mousapour Mamoudan M., Alipour-Vaezi M., Aghsami A., Jolai F., Yazdani M., Prioritizing post-disaster reconstruction projects using an integrated multi-criteria decision-making approach: A case study, Buildings, 12, 2, pp. 1-26, (2022); Mudassir G., DiMarco A., Social-Based city reconstruction planning in case of natural disasters: A reinforcement learning approach, Proceedings - 2021 IEEE 45th Annual Computers, Software, and Applications Conference, COMPSAC 2021, pp. 493-503, (2021); Nawari N.O., Ravindran S., Blockchain and Building Information Modeling (BIM): Review and applications in post-disaster recovery, Buildings, 9, 6, (2019); Nejat A., Cong Z., Liang D., Family structures, relationships, and housing recovery decisions after hurricane sandy, Buildings, 6, 2, (2016); Nejat A., Damnjanovic I., Modeling dynamics of post-disaster recovery, Construction Research Congress 2012: Construction Challenges in a Flat World, Proceedings of the 2012 Construction Research Congress, pp. 2200-2210, (2012); Nozhati S., A resilience-based framework for decision making based on simulation-optimization approach, Structural Safety, 89, (2021); Nozhati S., Sarkale Y., Ellingwood B., Chong E.K.P., Mahmoud H., Near-optimal planning using approximate dynamic programming to enhance post-hazard community resilience management, Reliability Engineering and System Safety, 181, pp. 116-126, (2019); Olshansky R.B., Johnson L.A., Horne J., Nee B., Longer view: Planning for the rebuilding of New Orleans, Journal of the American Planning Association, 74, 3, pp. 273-287, (2008); Ophiyandri T., Amaratunga R.D.G., Pathirage C.P., Community based post disaster housing reconstruction: Indonesian perspective, Proceedings of the CIB 2010, (2010); Opricovic S., Tzeng G.-H., Multicriteria planning of post-earthquake sustainable reconstruction, Computer-Aided Civil and Infrastructure Engineering, 17, 3, pp. 211-220, (2002); Ouyang M., Review on modeling and simulation of interdependent critical infrastructure systems, Reliability Engineering and System Safety, 121, pp. 43-60, (2014); Patel S., Hastak M., Molin Valdes H., A framework to construct post-disaster housing, International Journal of Disaster Resilience in the Built Environment, 4, 1, pp. 95-114, (2013); Pezzica C., Cutini V., Bleil de Souza C., Mind the gap: State of the art on decision-making related to post-disaster housing assistance, International Journal of Disaster Risk Reduction, 53, (2021); Rakes T.R., Deane J.K., Rees L.P., Fetter G.M., A decision support system for post-disaster interim housing, Decision Support Systems, 66, pp. 160-169, (2014); Rinaldi S.M., Peerenboom J.P., Kelly T.K., Identifying, Understanding, and analyzing critical infrastructure interdependencies, IEEE Control Systems Magazine, 21, 6, pp. 11-25, (2001); Rouhanizadeh B., Kermanshachi S., Investigating the relationships of socioeconomic factors delaying post-disaster reconstruction, Computing in Civil Engineering 2019: Smart Cities, Sustainability, and Resilience - Selected Papers from the ASCE International Conference on Computing in Civil Engineering 2019, pp. 33-40, (2019); Rouhanizadeh B., Kermanshachi S., Post-disaster reconstruction of transportation infrastructures: Lessons learned, Sustainable Cities and Society, 63, September, (2020); Safapour E., Adecision support system for success of post-hurricane reconstruction of transportation infrastructures, (2020); Safapour E., Kermanshachi S., Identification and categorization of factors affecting duration of post-disaster reconstruction of interdependent transportation systems, Construction Research Congress 2020: Computer applications - selected papers from the Construction Research Congress 2020, pp. 1290-1299, (2020); 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Witton F., Rasheed E.O., Rotimi J.O.B., Does leadership style differ between a post-disaster and non-disaster response project? a study of three major projects in New Zealand, Buildings, 9, 9, (2019); Yi H., Yang J., Research trends of post disaster reconstruction: The past and the future, Habitat International, 42, pp. 21-29, (2014); Zamanifar M., Hartmann T., Optimization-based decision-making models for disaster recovery and reconstruction planning of transportation networks, Natural Hazards, 104, 1, pp. 1-25, (2020); Zamanifar M., Seyedhoseyni S.M., Recovery planning model for roadways network after natural hazards, Natural Hazards, 87, 2, pp. 699-716, (2017); Zhang W., Wang N., Resilience-based risk mitigation for road networks, Structural Safety, 62, pp. 57-65, (2016); Zhao X., Cai H., Chen Z., Gong H., Feng Q., Assessing urban lifeline systems immediately after seismic disaster based on emergency resilience, Structure and Infrastructure Engineering, 12, 12, pp. 1634-1649, (2016)","S. Greenal; Department of Architecture and Planning, National Institute of Calicut, Kozhikode, India; email: sheringreenal.13@gmail.com","","Taylor and Francis Ltd.","","","","","","23789689","","","","English","Sustain. Resil. Infra.","Review","Final","","Scopus","2-s2.0-105001479071" -"Peerzadah S.A.","Peerzadah, Sabzar Ahmad (58084186600)","58084186600","Leadership and Followers' Innovative Work Behavior Relationship Research: Connecting the Dots Using Systematic Bibliometrics","2024","Journal of Innovation Management","12","3","","126","157","31","0","10.24840/2183-0606_012.003_0006","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85214111675&doi=10.24840%2f2183-0606_012.003_0006&partnerID=40&md5=9443ad0b8587143bb9a529341f7fb70d","UK-India Trade Project led by King’s College London, Indian Institute of Management, Bangalore, India; Department of Commerce, University of Kashmir, J&K, Srinagar, India","Peerzadah S.A., UK-India Trade Project led by King’s College London, Indian Institute of Management, Bangalore, India, Department of Commerce, University of Kashmir, J&K, Srinagar, India","Empirical research established that leadership is a critical determinant of followers’ innovative work behavior, and has reached a sufficient level of maturity to warrant a comprehensive review. However, the existing reviews frequently examined leadership and followers’ innovative work behavior (IWB) separately, resulting in a distorted picture of the development and relevance of their joint contribution. To address this gap, the paper aims to review the studies examining the relationships between leadership and IWB through a hybrid review. Hence, bibliometric analysis and systematic review were conducted to understand the phenomenon. The data analysis included performance analysis and science mapping by employing VOSviewer and bibliometrix, alongside content analysis of studies obtained from the Scopus database covering the period from 2008 to 2021. Results revealed that transformational leadership was most studied, followed by empowering, inclusive, and servant leadership. Most studies employ social exchange and social cognitive theory. The majority of the studies adopted a quantitative cross-sectional research design. The research examined the mediators and moderators utilized to explore the relationship between leadership and IWB and discovered variations in the empirical results. The prospects for future research are shown in terms of constructs, theoretical lenses, and methodologies. © 2024 Universidade do Porto - Faculdade de Engenharia. All rights reserved.","bibliometric analysis; innovative work behavior; leadership; systematic review","","","","","","","","Abualoush S., Obeidat A. M., Abusweilema M. A., Khasawneh M. M., How does entrepreneurial leadership promote Innovative work behaviour through mediating role of knowledge sharing and moderating role of person-job fit, International Journal of Innovation Management, 26, 1, pp. 1-27, (2022); Afsar B., Badir Y., Saeed B., Transformational leadership and innovative work behavior, Industrial Management and Data Systems, 114, 8, pp. 1270-1300, (2014); Afsar B., Masood M., Transformational Leadership, Creative Self-Efficacy, Trust in Supervisor, Uncertainty Avoidance, and Innovative Work Behavior of Nurses, The Journal of Applied Behavioral Science, 54, 1, pp. 36-61, (2018); Afsar B., Umrani W.A., Transformational leadership and innovative work behavior: The role of motivation to learn, task complexity and innovation climate, European Journal of Innovation Management, 23, 3, pp. 402-428, (2020); Afsar B., Masood M., Umrani W. A., The role of job crafting and knowledge sharing on the effect of transformational leadership on innovative work behavior, Personnel Review, 48, 5, pp. 1186-1208, (2019); Afsar B, Umrani WA., Does thriving and trust in the leader explain the link between transformational leadership and innovative work behaviour? A cross-sectional survey, Journal of Research in Nursing, 25, 1, pp. 37-51, (2020); Agarwal U. A., Examining the impact of social exchange relationships on innovative work behaviour: Role of work engagement, Team Performance Management, 20, 3–4, pp. 102-120, (2014); Agarwal U. A., Bhargava S., The role of social exchange on work outcomes: a study of Indian managers, The International Journal of Human Resource Management, 25, 10, pp. 1484-1504, (2014); AlEssa H. S., Durugbo C. M., Systematic review of innovative work behavior concepts and contributions, Management Review Quarterly, 72, 4, pp. 1171-1208, (2022); Ali I., Balta M., Papadopoulos T., Social media platforms and social enterprise: Bibliometric analysis and systematic review, International Journal of Information Management, (2022); Alfy S. E., Naithani P., Antecedents of innovative work behaviour: a systematic review of the literature and future research agenda, World Review of Entrepreneurship, Management and Sustainable Development, 17, 1, pp. 1-19, (2021); Amabile T. M., Conti R., Coon H., Lazenby J., Herron M., Assessing the work environment for creativity, Academy of Management Journal, 39, 5, pp. 1154-1184, (1996); Amabile T. M., Schatzel E. A., Moneta G. B., Kramer S. J., Leader behaviors and the work environment for creativity: Perceived leader support, The Leadership Quarterly, 15, 1, pp. 5-32, (2004); Amabile T. M., Khaire M., Creativity and the role of the leader, HarvardBusinessRev iew, 86, 10, pp. 100-109, (2008); Appio F. P., Cesaroni F., Di Minin A., Visualizing the structure and bridges of the intellectual property management and strategy literature: a document co-citation analysis, Scientometrics, 101, 1, pp. 623-661, (2014); Atatsi E. A., Stoffers J., Kil A., Team learning, Work behaviors, and performance: A qualitative case study of a Technical University in Ghana, Sustainability, 13, 24, (2021); Baber H., Nair K., Gupta R., Gurjar K., The beginning of ChatGPT – a systematic and bibliometric review of the literature, Information and Learning Sciences, (2023); Banker D. V., Garg S., Maggon M., Virtual Leadership: Bibliometrics, Framework-Based Systematic Review, and Future Agenda, South Asian Journal of Business and Management Cases, 12, 3, pp. 300-332, (2023); Baruah U., Raju T. 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Peerzadah; UK-India Trade Project led by King’s College London, Indian Institute of Management, Bangalore, India; email: sabzar.uok@gmail.com","","Universidade do Porto - Faculdade de Engenharia","","","","","","21830606","","","","English","J. Innov. Manag.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85214111675" -"Dragomir V.D.; Dumitru M.","Dragomir, Voicu D. (25228602200); Dumitru, Mădălina (31667475700)","25228602200; 31667475700","The state of the research on circular economy in the European Union: A bibliometric review","2024","Cleaner Waste Systems","7","","100127","","","","20","10.1016/j.clwas.2023.100127","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85181836148&doi=10.1016%2fj.clwas.2023.100127&partnerID=40&md5=5791245f2f7cc53e5ce342f505ef7218","The Bucharest University of Economic Studies, Bucharest, Romania","Dragomir V.D., The Bucharest University of Economic Studies, Bucharest, Romania; Dumitru M., The Bucharest University of Economic Studies, Bucharest, Romania","Before 2020, the European Commission adopted several strategies pursuing sustainable development in the European Union (EU). At the core of these strategies, we can find the circular economy (CE) which relies on the 3 R concept: reduce-reuse-recycle. Starting from the unique European regulatory context, the aim of the present review is to determine the degree to which the works published by researchers affiliated with institutions within the EU address the challenges identified at the EU level and respond to EU strategies in the field of the CE. A bibliometric analysis based on Scopus was performed using VOSviewer and the bibliometrix package in R. The sample is made up of 13,553 articles published between 2006 and 2023. The results show that there has been an increase in the number of articles and citations during the last years, in line with the adoption of relevant regulations. The co-word analysis generated five domain clusters: sustainable development and life cycle assessment; biomass production and waste valorization; materials and recycling; wastewater treatment and environmental pollution; carbon emissions reduction and energy recovery. Several topics are common to all EU countries, and they are strongly related to EU-wide strategies regarding the circular economy. The study has implications for standard-setters and research agencies, supporting the European Commission to understand the effects of the CE package implementation and what needs to be done in the future. © 2024 The Authors","Bibliometric analysis; Circular economy; Co-word analysis; European Union; Literature review; Regulatory framework; Science mapping; Scopus; Strategy","","","","","","","","Ailinca A.G., Piciu G., Chitiga G., Elaboration of a circular economy composite index for the EU27 countries, Post-Pandemic Realities and Growth in Eastern Europe, pp. 313-325, (2022); Ali H., Khan H.A., Pecht M.G., Circular economy of Li batteries: technologies and trends, J. 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Recycl., 183, (2022); Zabochnicka M., Krzywonos M., Romanowska-Duda Z., Szufa S., Darkalt A., Mubashar M., Algal biomass utilization toward circular economy, Life, 12, 10, (2022); Zhu Z., Liu W., Ye S., Batista L., Packaging design for the circular economy: a systematic review, Sustain. Prod. Consum., 32, pp. 817-832, (2022)","M. Dumitru; Bucharest, 6 Piața Romană, 1st district, 010374, Romania; email: madalina.dumitru@cig.ase.ro","","Elsevier B.V.","","","","","","27729125","","","","English","Clean. Waste. Syst.","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85181836148" -"Trejo-Castro A.I.; Martinez-Ledesma E.; Martinez-Torteya A.","Trejo-Castro, Alejandro I. (57193602188); Martinez-Ledesma, Emmanuel (55879032400); Martinez-Torteya, Antonio (36975929500)","57193602188; 55879032400; 36975929500","A bibliometric review on in silico drug repurposing: Performance analysis, science mapping and text mining (2000–2023)","2025","Heliyon","11","10","e42750","","","","0","10.1016/j.heliyon.2025.e42750","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105003227089&doi=10.1016%2fj.heliyon.2025.e42750&partnerID=40&md5=fb66141935c4f5ec39c10f696a07f041","Tecnológico de Monterrey, School of Medicine and Health Sciences, Nuevo León, Monterrey, 64710, Mexico; Tecnológico de Monterrey, Institute for Obesity Research, Nuevo León, Monterrey, 64710, Mexico; Universidad de Monterrey, School of Engineering and Technology, Nuevo León, San Pedro Garza García, 66238, Mexico","Trejo-Castro A.I., Tecnológico de Monterrey, School of Medicine and Health Sciences, Nuevo León, Monterrey, 64710, Mexico; Martinez-Ledesma E., Tecnológico de Monterrey, School of Medicine and Health Sciences, Nuevo León, Monterrey, 64710, Mexico, Tecnológico de Monterrey, Institute for Obesity Research, Nuevo León, Monterrey, 64710, Mexico; Martinez-Torteya A., Universidad de Monterrey, School of Engineering and Technology, Nuevo León, San Pedro Garza García, 66238, Mexico","Drug repositioning is a technique to investigate whether a drug already approved for one disease will function for another disease not included in the original design. This process has attracted much interest in the last two decades because it is less time-consuming and more cost-efficient than traditional drug discovery. Its impact has been observed mainly in the pandemic setting, where the severity and lack of cure or vaccine prompted the testing of existing drugs. This bibliometric study aims to show the conceptual and intellectual structure of the progress made in this field using computational or in silico techniques. We searched in Scopus in February 2024 and yielded a final database of 5320 articles, and then we filtered, cleaned, and harmonized the data. We analyzed the data with the help of Bibliometrix, Scimago Graphica, and custom code using R to underscore the most frequent journals, authors, countries, affiliations, and keywords. To determine the most studied diseases, we grouped similar terms (e.g., Alzheimer's disease, dementia) into clusters using a custom dictionary and analyzed their frequency trends over time. We highlight that the most reported databases in terms of keywords were Connectivity Map and DrugBank. The most studied diseases were COVID-19, cancer, infectious diseases (Chagas, malaria, tuberculosis), and neurological diseases such as Alzheimer's and Parkinson's. Overall, we concluded that drug repurposing will continue to be of interest and a realistic solution for drug discovery. © 2025 The Authors","Bioinformatics; Computational biology; Deep learning; Drug repurposing; In silico; Machine learning","","","","","","Universidad de Monterrey, UDEM; Secretaría de Ciencia, Humanidades, Tecnología e Innovación, (747650); Instituto Tecnológico y de Estudios Superiores de Monterrey, ITESM, (A00818219, IJXT070-23EG54001); Instituto Tecnológico y de Estudios Superiores de Monterrey, ITESM; Sistema Nacional de Investigadores, SNI, (377932); Sistema Nacional de Investigadores, SNI","Funding text 1: This work was partially supported by the Secretar\u00EDa de Ciencia, Humanidades, Tecnolog\u00EDa e Innovaci\u00F3n (Secihti) (scholarship number 747650) and by the Tecnol\u00F3gico de Monterrey (scholarship number A00818219 and Challenge-Based Research Funding Program project IJXT070-23EG54001).The funding for the publication of this paper was covered by Universidad de Monterrey. The sponsors had no role in the design, conduct of the study, data collection, analysis, interpretation, preparation of the manuscript, or review and approval of the manuscript.Alejandro I. Trejo-Castro thanks Secihti and Tecnol\u00F3gico de Monterrey, sponsors of his graduate studies, whose support made this manuscript possible. Antonio Martinez-Torteya also acknowledges Secihti and the Sistema Nacional de Investigadoras e Investigadores (SNII) for the support received as SNII level 1 (grant number 377932).; Funding text 2: This work was partially supported by the Secretar\u00EDa de Ciencia, Humanidades, Tecnolog\u00EDa e Innovaci\u00F3n (Secihti) (scholarship number 747650 ) and by the Tecnol\u00F3gico de Monterrey (scholarship number A00818219 and Challenge-Based Research Funding Program project IJXT070-23EG54001 ). ; Funding text 3: Antonio Martinez-Torteya also acknowledges Secihti and the Sistema Nacional de Investigadoras e Investigadores (SNII) for the support received as SNII level 1 (grant number 377932 ). 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Martinez-Ledesma; Tecnológico de Monterrey, Institute for Obesity Research, Monterrey, Nuevo León, 64710, Mexico; email: juanemmanuel@tec.mx; A. Martinez-Torteya; Universidad de Monterrey, School of Engineering and Technology, San Pedro Garza García, Nuevo León, 66238, Mexico; email: antonio.martinez@udem.edu","","Elsevier Ltd","","","","","","24058440","","","","English","Heliyon","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-105003227089" -"Khan D.; Verma M.K.; Yuvaraj M.","Khan, Daud (57226472723); Verma, Manoj Kumar (57190839871); Yuvaraj, Mayank (56019508500)","57226472723; 57190839871; 56019508500","Cluster analysis and network visualization of journals, authors, keywords, and themes of monkeypox research (1989–2022): an updated bibliometric review","2024","Library Hi Tech","42","6","","1905","1929","24","7","10.1108/LHT-12-2022-0559","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85162670889&doi=10.1108%2fLHT-12-2022-0559&partnerID=40&md5=65648f57e01b03d13a09e1cd74ac50bd","Maulana Azad Library, Aligarh Muslim University, Aligarh, India; Department of Library and Information Science, Mizoram University, Aizawl, India; Rajshri Janak Central Library, Central University of South Bihar, Gaya, India","Khan D., Maulana Azad Library, Aligarh Muslim University, Aligarh, India; Verma M.K., Department of Library and Information Science, Mizoram University, Aizawl, India; Yuvaraj M., Rajshri Janak Central Library, Central University of South Bihar, Gaya, India","Purpose: There have been numerous publications on human monkeypox since it was reported. With the help of bibliometric analysis, this study examined research hotspots and future trends related to human monkeypox. Science mapping was used in this study to identify influential monkeypox researchers, institutions, articles, keywords, thematic structures, and clusters of articles. Design/methodology/approach: Based on a validated search query, bibliometric analysis of data collected from Web of Science from 1989 to September 2022 was conducted. Using the “Title-Keyword-Abstract” search option, the search query consisted of keywords “Monkeypox” OR “Monkeypox virus” OR “monkeypox” OR “monkey pox” OR “MPXV.” With the state-of-the-art tools Bibliometrix package of R Studio and VOSviewer, performance analysis and science mapping, as a part of standard bibliometric research of monkeypox research were conducted. Findings: Researchers published 708 monkeypox papers from 1989 to September 2022, with American researchers publishing 460 papers. Further, USA had the highest international cooperation in terms of collaborative research output. Centers for Disease Control and Prevention (CDC) is a global leader in monkeypox research since it is the most prolific and collaborative organization. There have been the most published papers on monkeypox in the Journal of Virology. Damon Inger K is also the most prolific and influential researcher in monkeypox research, with the highest number of publications and citations. In total, 1,679 keywords were identified in the study. From the cluster analysis four themes were identified in monkeypox research. They are (1) clinical features, (2) monkeypox virus epidemiology, (3) monkeypox virus vaccine defense, and (4) monkeypox virus-related treatment measures. Originality/value: Analysis of collaboration, findings, networks of research, and visualization separates this study from traditional metrics analysis. Currently, there are no similar studies with similar objectives based on the authors' knowledge. © 2023, Emerald Publishing Limited.","Bibliometric analysis; Bibliometrix; Cluster analysis; Monkeypox; Network analysis; Science mapping; VOS viewer; Web of science","","","","","","","","Adeiza S., Shuaibu A., Trends in monkeypox research: a sixty year bibliometric analysis, Microbes and Infectious Diseases, 3, 3, pp. 500-513, (2022); Ahmad T., Murad M.A., Nasir S., Musa T.H., Baig M., Hui J., Trends in hepatitis A research indexed in the Web of Science: a bibliometric analysis over the period from 1985 to 2019, Human Vaccines and Immunotherapeutics, 17, 9, pp. 3221-3229, (2021); Alam S., Zardari S., Shamsi J., Comprehensive three-phase bibliometric assessment on the blockchain (2012-2020), Library Hi Tech, 41, 2, pp. 287-308, (2022); Antia R., Regoes R.R., Koella J.C., Bergstrom C.T., The role of evolution in the emergence of infectious diseases, Nature, 426, 6967, pp. 658-661, (2003); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Asemi A., Ko A., Asemi A., Infoecology of the deep learning and smart manufacturing: thematic and concept interactions, Library Hi Tech, 40, 4, pp. 994-1012, (2022); Baker R.O., Bray M., Huggins J.W., Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections, Antiviral Research, 57, 1-2, pp. 13-23, (2003); Balaei-Kahnamoei M., Al-Attar M., Khazaneha M., Raeiszadeh M., Ghorbannia-Dellavar S., Bagheri M., Salimi-Sabour E., Shahriary A., Arabfard M., Overview of herbal therapy of acute and chronic pulmonary disease: a conceptual map, Library Hi Tech, (2022); Banshal S.K., Verma M.K., Yuvaraj M., Quantifying global digital journalism research: a bibliometric landscape, Library Hi Tech, 40, 5, pp. 1337-1358, (2022); Bolanda J.D., Li Y., Reynolds M.G., Moudzeo H., Wassa D.W., Learned L.A., Libama F., Moudzeo H., Bolanda J.D., Tarangonia P., Boumandoki P., Formenty P., Harvey J.P., Damon I.K., Extended interhuman transmission of monkeypox in a hospital community in the Republic of the Congo, 2003, The American Journal of Tropical Medicine and Hygiene, 73, 2, pp. 428-434, (2005); Borgohain D.J., Nazim M., Verma M.K., Cluster analysis and network visualization of research in mucormycosis: a scientometric mapping of the global publications from 2011 to 2020, Library Hi Tech, (2022); Bosworth A., Wakerley D., Houlihan C.F., Atabani S.F., Monkeypox: an old foe, with new challenges, Infection Prevention in Practice, 4, 3, (2022); Bowden T.R., Babiuk S.L., Parkyn G.R., Copps J.S., Boyle D.B., Capripoxvirus tissue tropism and shedding: a quantitative study in experimentally infected sheep and goats, Virology, 371, 2, pp. 380-393, (2008); Bredahl L., Introduction to bibliometrics and current data sources, Library Technology Reports, 58, 8, pp. 5-11, (2022); Breman J.G., Johnson K.M., van der Groen G., Robbins C.B., Szczeniowski M.V., Ruti K., Webb P.A., Meier F., Heymann D.L., A search for ebola virus in animals in the democratic republic of the Congo and Cameroon: ecologic, virologic, and serologic surveys, 1979-1980, The Journal of Infectious Diseases, 179, s1, pp. S139-S147, (1999); Breman J.G., Kalisa-Ruti, Steniowski M.V., Zanotto E., Gromyko A.I., Arita I., Human monkeypox, 1970-79, Bulletin of the World Health Organization, 58, 2, pp. 165-182, (1980); Bunge E.M., Hoet B., Chen L., Lienert F., Weidenthaler H., Baer L.R., Steffen R., The changing epidemiology of human monkeypox—a potential threat? 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WHO Director-General’s statement at the press conference following IHR Emergency Committee regarding the multi-country outbreak of monkeypox - July 23 2022, (2022); Multi-country monkeypox outbreak in non-endemic countries, (2022); Wijewickrema M., A bibliometric study on library and information science and information systems literature during 2010-2019, Library Hi Tech, 41, 2, pp. 595-621, (2022); Xu X., Chen X., Jia F., Brown S., Gong Y., Xu Y., Supply chain finance: a systematic literature review and bibliometric analysis, International Journal of Production Economics, 204, pp. 160-173, (2018); Yan P., Li M., Li J., Lu Z., Hui X., Bai Y., Xun Y., Lao Y., Wang S., Yang K., Bibliometric analysis and systematic review of global coronavirus research trends before COVID-19: prospects and implications for COVID-19 research, Frontiers in Medicine, 8, (2021); Yang G., Pevear D.C., Davies M.H., Collett M.S., Bailey T., Rippen S., Barone L., Burns C., Rhodes G., Tohan S., Huggins J.W., Baker R.O., Buller R.L.M., Touchette E., Waller K., Schriewer J., Neyts J., DeClercq E., Jones K., Hruby D., Jordan R., An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus challenge, Journal of Virology, 79, 20, pp. 13139-13149, (2005); Yu Y., Li Y., Zhang Z., Gu Z., Zhong H., Zha Q., Yang L., Zhu C., Chen E., A bibliometric analysis using VOSviewer of publications on COVID-19, Annals of Translational Medicine, 8, 13, (2020); Zaucha G.M., Jahrling P.B., Geisbert T.W., Swearengen J.R., Hensley L., The pathology of experimental aerosolized monkeypox virus infection in cynomolgus monkeys (Macaca fascicularis), Laboratory Investigation, 81, 12, pp. 1581-1600, (2001); Zeeshan H.M., Rubab A., Dhlakama H., Ogunsakin R.E., Okpeku M., Global research trends on monkeypox virus: a bibliometric and visualized study, Tropical Medicine and Infectious Disease, 7, 12, (2022); Zhang Y., Zhang J.-Y., Wang F.-S., Monkeypox outbreak: a novel threat after COVID-19?, Military Medical Research, 9, 1, (2022); Zhao H., Wang W., Zhao L., Ye S., Song J., Lu R., Zong H., Wu C., Huang W., Huang B., Deng Y.A., Ruhan W., Qi L., Xu W., Ling H., Tan W., The first imported case of monkeypox in the mainland of China — Chongqing municipality, China CDC Weekly, 4, 38, pp. 853-854, (2022)","M. Yuvaraj; Rajshri Janak Central Library, Central University of South Bihar, Gaya, India; email: mayank.yuvaraj@gmail.com","","Emerald Publishing","","","","","","07378831","","","","English","Libr. Hi Tech","Review","Final","","Scopus","2-s2.0-85162670889" -"Kumar D.; Piramanayagam S.; Shandilya A.K.","Kumar, Dilip (59116291900); Piramanayagam, Senthilkumaran (57209853987); Shandilya, Abhinav Kumar (58079894200)","59116291900; 57209853987; 58079894200","Journey of Journal of Accessibility and Design for All: A Review","2025","Journal of Accessibility and Design for All","15","1","","87","106","19","0","10.17411/jacces.v15i1.573","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105005972040&doi=10.17411%2fjacces.v15i1.573&partnerID=40&md5=84927413a432713a594900b86363fe9c","Great Lakes Institute of Management, Gurgaon, India; Welcomgroup Graduate School of Hotel Administration, Manipal Academy of Higher Education, Manipal, India; Birla Institute of Technology, Ranchi, India","Kumar D., Great Lakes Institute of Management, Gurgaon, India; Piramanayagam S., Welcomgroup Graduate School of Hotel Administration, Manipal Academy of Higher Education, Manipal, India; Shandilya A.K., Birla Institute of Technology, Ranchi, India","This study aims to examine the publication journey of the Journal of Accessibility and Design for All (JACCES). This review article utilised bibliometric analysis to conduct performance evaluation and science mapping. The study employed the Bibliometrix R package (version 4.2.3) through the Biblioshiny interface, along with VOSviewer, to address the research questions. The performance analysis focused on the publication trends, citations, and contributions from authors, institutions, and countries of the JACCES. In addition, keyword co-occurrence and bibliographic coupling analyses were performed to measure the conceptual structure of the literature and the central themes on which the journal has published. The study identifies four themes: inclusive design and tourism for all, accessible tourism: sensory and digital approaches, measuring and evaluating disability-inclusive environments, and digital accessibility in public domains. A future research agenda is also proposed for researchers to work on and provide comprehensive information to fill the research gaps and strengthen the publication journey of the JACCES. © Journal of Accessibility and Design for All (JACCES), DOI: https://doi.org/.","bibliographic coupling; biblioshiny; JACCES; Journal of Accessibility and Design for All; performance analysis; science mapping; VOSviewer","","","","","","","","Abdeldayem N., Al Tal R., Gharaibeh A., Using geographic information systems to study the impact of the built environment on social inclusion of people with physical disabilities: The case of Amman, A/Z ITU Journal of the Faculty of Architecture, 19, 3, pp. 569-583, (2022); Alahmadi T., Drew S., Evaluation of image accessibility for visually impaired users, Journal of Accessibility and Design for All, 8, 2, pp. 125-160, (2018); Antia-Obong S. E., Casselden B., Pickard A., A bibliometric analysis of Journal of Higher Education Management (JHEM) from 2007 to 2016, Library Philosophy and Practice, (2019); Arfaoui A., Edwards G., Morales E., Fougeyrollas P., Understanding risk in daily life of diverse persons with physical and sensory impairments, Journal of Accessibility and Design for All, 9, 1, pp. 66-89, (2019); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bender A. C., Rosa M. P., Lopes A. C., Flores A., The Symbolism of the door Knocker “Hand Of Fatima”: A proposal of sensory tourist experiences in the City of Lagos, Journal of Accessibility and Design for All, 11, 2, pp. 232-258, (2021); Bianco L., Universal design: From design philosophy to applied science, Journal of Accessibility and Design for All, 10, 1, pp. 70-97, (2020); Broadus R. N., Toward a definition of “bibliometrics, Scientometrics, 12, 5, pp. 373-379, (1987); Buhler C., Design for All – from Idea to Practise, Computers Helping People with Special Needs. ICCHP 2008. Lecture Notes in Computer Science, 5105, (2008); Buhler C., Stephanidis C., European Co-operation Activities Promoting Design for All in Information Society Technologies, Computers Helping People with Special Needs. ICCHP 2004. Lecture Notes in Computer Science, 3118, (2004); Callon M., Courtial J.-P., Turner W. A., Bauin S., From translations to problematic networks: An introduction to co-word analysis, Social Science Information, 22, 2, pp. 191-235, (1983); Chan F., Iwanaga K., Tansey T. N., Ditchman N., Wehman P., Wu J. R., Chen X., Assessing Evidence-Based Disability Inclusion Policy and Practices to Promote Employment of People With Disabilities in the Workplace: Scale Development and Validation, Rehabilitation Counseling Bulletin, (2024); Cheng F.-F., Huang Y.-W., Yu H.-C., Wu C.-S., Mapping knowledge structure by keyword co-occurrence and social network analysis, Library Hi Tech, 36, 4, pp. 636-650, (2018); Debevc M., Skraba T., Cerovac B., Kozuh I., Rajh N., Monitoring website accessibility: Evaluating current approaches and a proposal for improvements, Journal of Accessibility and Design for All, 13, 2, pp. 162-187, (2023); Di Bucchianico G., Design for All. The Increasing Dissemination of Teaching Experiences, Advances in Design for Inclusion. AHFE 2017. Advances in Intelligent Systems and Computing, 587, (2018); Dominguez Vila T., Alen Gonzalez E., Darcy S., Accessible tourism online resources: a Northern European perspective, Scandinavian Journal of Hospitality and Tourism, 19, 2, pp. 140-156, (2019); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Donthu N., Kumar S., Pandey N., Gupta P., Forty years of the International Journal of Information Management: A bibliometric analysis, International Journal of Information Management, 57, (2021); Donthu N., Kumar S., Pattnaik D., Forty-five years of Journal of Business Research: A bibliometric analysis, Journal of Business Research, 109, pp. 1-14, (2020); Egghe L., Theory and practise of the g-index, Scientometrics, 69, 1, pp. 131-152, (2006); Ellegaard O., Wallin J. A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, 3, pp. 1809-1831, (2015); Eusebio C., Silveiro A., Teixeira L., Website accessibility of travel agents: An evaluation using web diagnostic tools, Journal of Accessibility and Design for All: JACCES, 10, 2, pp. 180-208, (2020); Gaire N., Sharifi M. S., Christensen K., Chen A., Song Z., Walking behavior of individuals with and without disabilities at right-angle turning facility, Journal of Accessibility and Design for All, 7, 1, pp. 56-75, (2017); Gamache S., Grenier Y., Fougeyrollas P., Edwards G., Mostafavi M. A., Developing a taxonomy of the built environment for disability studies. Methodological insights, Journal of Accessibility and Design for All, 7, 2, pp. 236-265, (2017); Gamache S., Morales E., Noreau L., Dumont I., Leblond J., Measure of environmental accessibility (MEA): Development and inter-rater reliability, Journal of Accessibility and Design for All, 8, 1, pp. 1-32, (2018); Gamache S., Routhier F., Morales E., Vandersmissen M.-H., Leblond J., Boucher N., James McFadyen B., Noreau L., Municipal practices and needs regarding accessibility of pedestrian infrastructures for individuals with physical disabilities in Québec, Canada, Journal of Accessibility and Design for All, 7, 1, pp. 21-56, (2017); Gamache S., Routhier F., Mortenson W. Ben, Lacroix E., Miller W. C., Ginis K. A. M., Objective evaluation of environmental obstacles encountered in two canadian urban settings by mobility device users, Journal of Accessibility and Design for All, 10, 1, pp. 98-123, (2020); Gheno G., BIBLIOBICLUSTER: A Bicluster Algorithm for Bibliometrics, IFIP Advances in Information and Communication Technology, 627, pp. 271-282, (2021); Gillovic B., McIntosh A., Accessibility and inclusive tourism development: Current state and future agenda, Sustainability (Switzerland), 12, 22, pp. 1-15, (2020); Gurung D. J., Gowreesunkar V., Mapping the landscape of tourism cities research: a bibliometric analysis of the International Journal of Tourism Cities, International Journal of Tourism Cities, 10, 1, pp. 213-239, (2024); Henriquez C. S., Ricoy Cano A. J., Galan J. H., de la Fuente Robles Y. M., The past, present, and future of accessible tourism research, Journal of Accessibility and Design for All, pp. 26-61, (2022); Hirsch J. E., An index to quantify an individual’s scientific research output, Proceedings of the National Academy of Sciences of the United States of America, 102, 46, pp. 16569-16572, (2005); Hitch D., Dell K., Larkin H., Does universal design education impact on the attitudes of architecture students towards people with disability?, Journal of Accessibility and Design for All, 6, 1, pp. 26-48, (2016); Iniesto F., Rodrigo C., A preliminary study for developing accessible MOOC services, Journal of Accessibility and Design for All, 6, 2, pp. 126-150, (2016); Jackson M. A., Models of Disability and Human Rights: Informing the Improvement of Built Environment Accessibility for People with Disability at Neighborhood Scale?, Laws, 7, 1, (2018); Khasawneh M. A. S., Digital Inclusion: Analyzing Social Media Accessibility Features for Students with Visual Impairments, Studies in Media and Communication, 12, pp. 71-78, (2024); Kose S., Built environment design toward an inclusive society: How can we improve the existing infrastructure in cities?, Advances in Intelligent Systems and Computing, 500, pp. 307-313, (2016); Kumar A., Sharma S., Vashistha R., Srivastava V., Tabash M. I., Munim Z. H., Paltrinieri A., International Journal of Emerging Markets: a bibliometric review 2006–2020, International Journal of Emerging Markets, 19, 4, pp. 1051-1089, (2024); Kumar D., Shandilya A. K., Srivastava S., The journey of F1000Research since inception: through bibliometric analysis, F1000Research, 12, pp. 1-27, (2023); Lim W. M., Kumar S., Pandey N., Verma D., Kumar D., Evolution and trends in consumer behaviour: Insights from Journal of Consumer Behaviour, Journal of Consumer Behaviour, 22, 1, pp. 217-232, (2023); Lotka A. J., The frequency distribution of scientific productivity, Journal of the Washington Academy of Sciences, 16, 12, pp. 317-323, (1926); Martin A, Watchorn Valerie, Grant C, Changing Places, Changing Lives, Journal contribution, (2018); Mosca E. I., Herssens J., Rebecchi A., Capolongo S., Inspiring architects in the application of design for all: knowledge transfer methods and tools, Journal of Accessibility and Design for All, 9, 1, pp. 1-24, (2019); Mukherjee D., Lim W. M., Kumar S., Donthu N., Guidelines for advancing theory and practice through bibliometric research, Journal of Business Research, 148, pp. 101-115, (2022); Muller L., Erdtman E., Hedvall P.-O., Is the city planned and built for me? Citizens’ experiences of inclusion, exclusion and (un) equal living conditions in the built environment, Journal of Accessibility and Design for All, 14, 1, pp. 32-51, (2024); Offei L., Acheampong E., Appiah-Brempong E., Okyere P., Owusu I., Accessibility of tourist sites to people with disabilities: The case of cape coast and elmina castles in Ghana, Journal of Accessibility and Design for All, 7, 2, pp. 127-158, (2017); Palmer Peterson H., Built environment accessibility in the eastern province of the kingdom of saudi arabia as seen by persons with disabilities, Journal of Accessibility and Design for All, 11, 1, pp. 115-147, (2021); Pandey N., Andres C., Kumar S., Mapping the corporate governance scholarship: Current state and future directions, Corporate Governance: An International Review, 31, 1, pp. 127-160, (2023); Pascual A., Ribera M., Granollers T., Impact of accessibility barriers on the mood of users with motor and dexterity impairments, Journal of Accessibility and Design for All, 5, 1, pp. 1-26, (2015); Paul J., Criado A. R., The art of writing literature review: What do we know and what do we need to know?, International Business Review, 29, 4, (2020); Piramanayagam S., Pritam P., More B. A., Inclusive hotel design in India: A user perspective, Journal of Accessibility and Design for All, 9, 1, pp. 41-65, (2019); Pritchard A., Statistical bibliography or bibliometrics, Journal of Documentation, 25, (1969); Rahmatizadeh S., Valizadeh-Haghi S., Monitoring for accessibility in medical university websites: Meeting the needs of people with disabilities, Journal of Accessibility and Design for All, 8, 2, pp. 102-124, (2018); Rolim A. M., Pinto V. D., Rosa M. P., Birdwatching and birding by ear: An accessible and inclusive tourism proposal for the city of lagos, Journal of Accessibility and Design for All, 11, 1, pp. 48-85, (2021); Rosa M. P., De Mello G. S., Morato S., Tactile paving surfaces at bus stops: The need of homogeneous technical solutions for accessible tourism, Journal of Accessibility and Design for All, 11, 2, pp. 259-294, (2021); Sabev N., Georgieva-Tsaneva G., Bogdanova G., Research, analysis, and evaluation of web accessibility for a selected group of public websites in Bulgaria, Journal of Accessibility and Design for All, 10, 1, pp. 124-160, (2020); Sharma G. D., Taheri B., Gupta M., Chopra R., Over 33 years of the hospitality research: a bibliometric review of the International Journal of Contemporary Hospitality Management, International Journal of Contemporary Hospitality Management, 35, 7, pp. 2564-2589, (2023); Stitz T., Blundell S., Evaluating the accessibility of online library guides at an academic library, Journal of Accessibility and Design for All, 8, 1, pp. 33-79, (2018); Suarez Henriquez C., Ricoy Cano A. J., Hernandez Galan J., de la Fuente Robles Y. M., The past, present, and future of accessible tourism research: A bibliometric analysis using the SCOPUS database, Journal of Accessibility and Design for All, 12, 1, pp. 26-60, (2022); Terashima M., Clark K., Measuring economic benefits of accessible spaces to achieve ‘meaningful access’ in the built environment: A review of recent literature, Journal of Accessibility and Design for All, 11, 2, pp. 195-231, (2021); Thelwall M., Kousha K., Abdoli M., Stuart E., Makita M., Wilson P., Levitt J., Which international co‐authorships produce higher quality journal articles?, Journal of the Association for Information Science and Technology, 75, 7, pp. 769-788, (2024); Trotta R., Vatican museums’ accessibility practices for Blind and Partially Sighted (BPS) visitors: A case study, Journal of Accessibility and Design for All, 13, 2, pp. 113-139, (2023); van Eck N. J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, pp. 523-538, (2010); Vieira G. C., Manita C. B., Ribeiro C., Rosa M. P., Digital literacy of elderly tourists in the Algarve destination, Journal of Accessibility and Design for All, 12, 2, pp. 180-211, (2022); Zimmermann-Janschitz S., Geographic Information Systems in the context of disabilities, Journal of Accessibility and Design for All, 8, 2, pp. 161-192, (2018)","","","Universitat Politecnica de Catalunya","","","","","","20137087","","","","English","J. Access. Des. All","Article","Final","","Scopus","2-s2.0-105005972040" -"Radebe F.M.; Njenga K.","Radebe, Fani Moses (57191838251); Njenga, Kennedy (55447649900)","57191838251; 55447649900","Bibliometric Mapping of Scientific Production and Conceptual Structure of Cyber Sextortion in Cybersecurity","2025","Social Sciences","14","1","12","","","","0","10.3390/socsci14010012","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85215793265&doi=10.3390%2fsocsci14010012&partnerID=40&md5=d9221fa36d2904cb7bd9d3745f5766e6","Department of Applied Information Systems, University of Johannesburg, Johannesburg, P.O. Box 524, South Africa","Radebe F.M., Department of Applied Information Systems, University of Johannesburg, Johannesburg, P.O. Box 524, South Africa; Njenga K., Department of Applied Information Systems, University of Johannesburg, Johannesburg, P.O. Box 524, South Africa","This study examines cyber sextortion research using a comprehensive bibliometric analysis. In the field of cybersecurity, cyber sextortion is a form of cybercrime that leverages privacy violations to exploit a victim. This study reviewed research developments on cyber sextortion progressively over time by looking at scientific productions, thematic developments, scholars’ contributions, and the future thematic trajectory. A bibliometric approach to analyzing the data was applied, which covered 548 peer-reviewed articles, conference papers, and book chapters retrieved from the Scopus database. Results showed a growth trajectory on various thematic concerns in the cyber sextortion field, which has continued to gain traction since the year 2023. Notably, online child sexual abuse is a growing theme in cyber sextortion research. In addition, among other themes, adolescents, mental health, and dating violence are receiving interest among scholars in this field. Additionally, institutions and prolific scholars from countries such as the United States of America, Australia, and the United Kingdom have established research collaborations to improve understanding in this field. The results also showed that research is observed to be emerging from South Africa and Ghana in the African region. Overall, there is potential for more scientific publications and researchers from Africa to contribute to this growing field. The value this study holds is moving beyond deficit-based approaches to how adolescent youth can be resilient and protected from cyber sextortion. A call for a multidisciplinary approach that moves beyond deficit-based approaches toward resilient and autonomy-based approaches is encouraged so that adolescent youth are protected from exploitation. This approach should focus on investigating proactive and resilience-based interventions informed by individuals’ traits and contexts to aid in building digital resilience in adolescents. © 2024 by the authors.","bibliometric analysis; bibliometrix R package; biblioshiny; coercive sexting; cyber sextortion; research trends; romance scam; science mapping","","","","","","","","Agbo F.J., Solomon O.S., Jarkko S., Markku T., Scientific production and thematic breakthroughs in smart learning environments: A bibliometric analysis, Smart Learning Environments, 8, (2021); Almeida T.C., Barreiros I., Online grooming among Portuguese adolescents and the COVID-19 lockdown: Relationship with other types of victimization, Children and Youth Services Review, 156, (2024); Alsoubai A., Razi A., Agha Z., Ali S., Stringhini G., Choudhury M.D., Wisniewski P.J., Profiling the offline and online risk experiences of youth to develop targeted interventions for online safety, Proceedings of the ACM on Human-Computer Interaction, 8, pp. 1-37, (2024); Angori G., Chiara M., Laura R., Ugo R., A patent-based analysis of the evolution of basic, mission-oriented, and applied research in European universities, The Journal of Technology Transfer, 49, pp. 609-641, (2024); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, pp. 959-975, (2017); Baas J., Michiel S., Andrew P., Gregoire C., Reza K., Scopus as a curated, high-quality bibliometric data source for academic research in quantitative science studies, Quantitative Science Studies, 1, pp. 377-386, (2020); Bhagat P.R., Farheen N., Robert M., Artificial intelligence solutions enabling sustainable agriculture: A bibliometric analysis, PLoS ONE, 17, (2022); Bornmann L., Mutz R., Growth rates of modern science: A bibliometric analysis based on the number of publications and cited references, Journal of the Association for Information Science and Technology, 66, pp. 2215-2222, (2015); Bucci S., Varese F., Quayle E., Cartwright K., Machin M., Whelan P., Chitsabesan P., Richards C., Green V., Norrie J., Et al., A Digital Intervention to Improve Mental Health and Interpersonal Resilience in Young people who have experienced technology-assisted sexual abuse: Protocol for a Nonrandomized Feasibility Clinical Trial and Nested qualitative study, Journal of Medical Internet Research on Research Protocols, 12, (2023); Buchanan T., Whitty M.T., The online dating romance scam: Causes and consequences of victimhood, Psychology, Crime and Law, 20, pp. 261-283, (2014); Caarten A.B., Heugten L.V., Ortrun M., The intersection of corruption and gender-based violence: Examining the gendered experiences of sextortion during migration to South Africa, African Journal of Reproductive Health, 6, pp. 45-54, (2022); Carlton A., Sextortion: The Hybrid Cyber-Sex Crime, North Carolina Journal of Law and Technology, 21, (2019); Champion A.R., Oswald F., Khera D., Pedersen C.L., Examining the gendered impacts of technology-facilitated sexual violence: A mixed methods approach, Archives of Sexual Behavior, 51, pp. 1607-1624, (2022); Choi H., Ouytsel J.V., Temple J.R., Association between sexting and sexual coercion among female adolescents, Journal of Adolescence, 53, pp. 164-168, (2016); Couch D., Liamputtong P., Pitts M., What are the real and perceived risks and dangers of online dating? Perspectives from online daters: Health risks in the media, Health, Risk and Society, 14, pp. 697-714, (2012); Cross C., No laughing matter: Blaming the victim of online fraud, International Review of Victimology, 21, pp. 187-204, (2015); Cross C., Blackshaw D., Improving the police response to online fraud, Policing: A Journal of Policy and Practice, 9, pp. 119-128, (2015); Cross C., Molly D., Kelly R., Understanding romance fraud: Insights from domestic violence research, The British Journal of Criminology, 58, pp. 1303-1322, (2018); Cross C., Holt K., Holt T.J., To pay or not to pay: An exploratory analysis of sextortion in the context of romance fraud, Criminology and Criminal Justice, (2023); Drouin M., Ross J., Tobin E., Sexting: A new, digital vehicle for intimate partner aggression?, Computers in Human Behavior, 50, pp. 197-204, (2015); Edwards M., Hollely N.M., Online sextortion: Characteristics of offences from a decade of community reporting, Journal of Economic Criminology, 2, (2023); Esfahani H.J., Tavasoli K., Jabbarzadeh A., Big data and social media: A scientometrics analysis, International Journal of Data and Network Science, 3, pp. 145-164, (2019); Fair J.E., Tully M., Ekdale B., Asante R.K., Crafting lifestyles in urban Africa: Young Ghanaians in the world of online friendship, Africa Today, 55, pp. 28-49, (2009); Fakunmoju S.B., Abrefa-Gyan T., Maphosa N., Gutura P., Rape myth acceptance: Gender and cross-national comparisons across the United States, South Africa, Ghana, and Nigeria, Sexuality & Culture, 25, pp. 18-38, (2021); Filice E., Matharu A., Parry D.C., Johnson C.W., A Thousand Catcalls: Survivors’ Experiences of Sexual Violence in Online Dating, Leisure Sciences, pp. 1-19, (2024); Foster A., Australian Teenagers Targeted by Sick Sextortion Scams. News.com.au, (2023); Gasso A.M., Klettke B., Agustina J.R., Montiel I., Sexting, mental health, and victimization among adolescents: A literature review, International Journal of Environmental Research and Public Health, 16, (2019); Gamez-Guadix M., Mateos-Perez E., Wachs S., Wright M., Martinez J., Incera D., Assessing image-based sexual abuse: Measurement, prevalence, and temporal stability of sextortion and nonconsensual sexting (“revenge porn”) among adolescents, Journal of Adolescence, 94, pp. 789-799, (2022); Gamez-Guadix M., Santisteban P., Resett S., Sexting among Spanish adolescents: Prevalence and personality profiles, Psicothema, 29, pp. 29-34, (2017); Grant J., Cottrell R., Cluzeau F., Fawcett G., Evaluating “payback” on biomedical research from papers cited in clinical guidelines: Applied bibliometric study, British Medical Journal, 320, pp. 1107-1111, (2000); Hagglund K., Khan F., The Gendered Impact of Corruption: Women as Victims of Sextortion in South Africa, Journal of Anti-Corruption Law, 7, (2023); Hamdi Bacha Y., Online Child Sexual Abuse: Exploring Psychological and Social Impacts, Prevention, and Intervention Strategies, Journal of Studies in Deviation Psychology, 9, pp. 903-915, (2024); Hasumi T., Chiu M.-S., Technology-enhanced language learning in English language education: Performance analysis, core publications, and emerging trends, Cogent Education, 11, (2024); Henry N., Powell A., Technology-facilitated sexual violence: A literature review of empirical research, Trauma, Violence, and Abuse, 19, pp. 195-208, (2018); Henry N., Gavey N., Johnson K., Image-based sexual abuse as a means of coercive control: Victim-survivor experiences, Violence Against Women, 29, pp. 1206-1226, (2023); Hlongwane P., Sextortion in South African public sector institutions, Sabinet African Journals, 25, pp. 7-25, (2017); Hong S., Lu N., Wu D., Jimenez D.E., Milanaik R.L., Digital sextortion: Internet predators and pediatric interventions, Current Opinion in Pediatrics, 32, pp. 192-197, (2020); Humphreys K., Clair B.L., Hicks J., Intersections between pornography and human trafficking: Training ideas and implications, Journal of Counselor Practice, 10, pp. 19-39, (2019); Jia H., Wisniewski P.J., Xu H., Rosson M.B., Carroll J.M., Risk-taking as a learning process for shaping teen’s online information privacy behaviors, Paper presented at the 18th ACM Conference on Computer Supported Cooperative Work & Social Computing, (2015); Kavishe A., The contribution of digital technology in exacerbating gender-based violence against female students in higher learning institutions in Tanzania, African Journal of Social Issues, 7, pp. 756-769, (2024); Kernsmith P.D., Victor B.G., Smith-Darden J.P., Online, offline, and over the line: Coercive sexting among adolescent dating partners, Youth and Society, 50, pp. 891-904, (2018); Kibe L., Kwanya T., Kogos A., Ogolla E., Onsare C., Types of Cyberbullying Experienced on Facebook by Undergraduate Students in Kenyan Universities, Journal of Cyberspace Studies, 6, pp. 149-182, (2022); Klettke B., Hallford D.J., Clancy E., Mellor D.J., Toumbourou J.W., Sexting and psychological distress: The role of unwanted and coerced sexts. Cyberpsychology, Behavior, and Social Networking, 22, pp. 237-242, (2019); Larsen P., von Ins M., The steady growth of scientific publication and the declining coverage provided by science citation index, Paper presented at the 12th International Conference on Scientometrics and Informetrics, (2009); Lastdrager E., Achieving a consensual definition of phishing based on a systematic review of the literature, Crime Science, 3, (2014); Liggett R., Exploring Online Sextortion, Family and Intimate Partner Violence Quarterly, 11, (2019); Mainwaring C., Scott A.J., Gabbert F., Facilitators and barriers of bystander intervention intent in image-based sexual abuse contexts: A focus group study with a university sample, Journal of Interpersonal Violence, 39, pp. 2655-2686, (2024); Mazanderani F., An ethics of intimacy: Online dating, viral-sociality and living with HIV, BioSocieties, 7, pp. 393-409, (2012); McGlynn C., Rackley E., Houghton R., Beyond ‘revenge porn’: The continuum of image-based sexual abuse, Feminist Legal Studies, 25, pp. 25-46, (2017); Mondal H., Sahoo M.R., Mondal S., Characteristics of Cyber Sextortion in India: Content Analysis of Online Newspapers Published in 2019–2021, Journal of Psychosexual Health, 4, pp. 171-177, (2022); Morelli M., Bianchi D., Baiocco R., Pezzuti L., Chirumbolo A., Not-allowed sharing of sexts and dating violence from the perpetrator’s perspective: The moderation role of sexism, Computers in Human Behavior, 56, pp. 163-169, (2016); Mori C., Cooke J.E., Temple J.R., Ly A., Lu Y., Anderson N., Rash C., Madigan S., The Prevalence of Sexting behaviours Among Emerging Adults: A Meta-Analysis, Archives of Sexual Behavior, 49, pp. 1103-1119, (2020); Muslimin J., Shodiq S., Almutairi T.H.M., Sextortion, Gender, and Digital Crime: A Socio-Legal Comparison between Positive and Islamic Law, AL-IHKAM: Journal Hukum and Pranata Sosial, 19, pp. 53-77, (2024); Newman J., Promoting interdisciplinary research collaboration: A Systematic Review, a critical literature Review, and a pathway forward, Social Epistemology, 38, pp. 135-151, (2024); Notte R.J., Exploring the impact of sextortion on adult males: A narrative approach, Technology in Society, 78, (2024); O'Malley R.L., Holt K.M., Cyber sextortion: An exploratory analysis of different perpetrators engaging in a similar crime, Journal of Interpersonal Violence, 37, pp. 258-283, (2022); Patchin J.W., Hinduja S., Sextortion among adolescents: Results from a national survey of US youth, Sexual Abuse, 32, pp. 30-54, (2020); Penner F., Gambin M., Sharp C., Childhood maltreatment and identity diffusion among inpatient adolescents: The role of reflective function, Journal of Adolescence, 76, pp. 65-74, (2019); Pethers B., Bello A., Role of Attention and Design Cues for Influencing Cyber-Sextortion Using Social Engineering and Phishing Attacks, Future Internet, 15, (2023); Power V., Bello A., Individual differences in cyber security behavior using personality-based models to predict susceptibility to sextortion attacks, Cybersecurity and Cognitive Science, pp. 89-113, (2022); Prell C., Hubacek K., Reed M., Stakeholder analysis and social network analysis in natural resource management, Society and Natural Resources, 22, pp. 501-518, (2009); Qi C., Yang N., Digital resilience in Chinese adolescents: A portrayal of the current condition, influencing factors, and improvement strategies, Frontiers in Psychiatry, 15, (2024); Ray A., Henry N., Sextortion: A Scoping Review, Trauma, Violence, and Abuse, 26, pp. 138-155, (2024); Radberg K.K., Lofsten H., The entrepreneurial university and development of large-scale research infrastructure: Exploring the emerging university function of collaboration and leadership, The Journal of Technology Transfer, 49, pp. 334-366, (2024); Ross J.M., Michelle D., Amanda C., Sexting coercion as a component of intimate partner polyvictimization, Journal of Interpersonal Violence, 34, pp. 2269-2291, (2019); Sage M., Randolph K., Fitch D., Sage T., Internet use and resilience in adolescents: A systematic review, Research on Social Work Practice, 31, pp. 171-179, (2021); Schoeps K., Peris-Hernandez M., Garaigordobil M., Montoya-Castilla I., Risk factors for being a victim of online grooming in adolescents, Psicothema, 32, pp. 15-23, (2020); Setyawati L.M., Hamka M., Digital resilience: Opportunities and threats for adolescents in A virtual world, Acta Informatica Malaysia (AIM), 2, pp. 67-71, (2022); Singh V.K., Singh P., Karmakar M., Leta J., Mayr P., The journal coverage of Web of Science, Scopus and Dimensions: A comparative analysis, Scientometrics, 126, pp. 5113-5142, (2021); Song Y., Chen X., Tianyong H., Liu Z., Zixin L., Exploring two decades of research on classroom dialogue by using bibliometric analysis, Computers in Education, 137, pp. 12-31, (2019); Sorell T., Whitty M.T., Online romance scams and victimhood, Security Journal, 32, pp. 342-361, (2019); Tasbiha N.S., Qualitatively Examining and Analyzing Social Learning Theory in an Online Arena with a Focus on Sexting, European Journal of Humanities and Social Sciences, 4, pp. 9-14, (2024); Tettey W.J., Globalization and Internet Fraud in Ghana: Interrogating the Political Economy of Survival, Subaltern Agency, and their Ramifications, Neoliberalism and Globalization in Africa: Contestations from the Embattled Continent, pp. 241-266, (2008); Thompson O., Aina O.S., Idris R.T., Ademola E.O., Akinreti-Raji B., Awange P.D., Oladele S.O., Are you gonna cooperate with me or i release your nude’: Sextortion, responses and implications for national development in Nigeria?, Ochendo: An African Journal of Innovative Studies, 5, pp. 8-26, (2024); Sextortion Summary Findings from a 2017 Survey of 2097 Survivors (No. 121919), (2017); Van Ouytsel J., Gool E.V., Walrave M., Ponnet K., Peeters E., Sexting: Adolescents’ perceptions of the applications used for, motives for, and consequences of sexting, Journal of Youth Studies, 20, pp. 446-470, (2017); Vitis L., Private, hidden and obscured: Image-based sexual abuse in Singapore, Asian Journal of Criminology, 15, pp. 25-43, (2020); Waheed H., Hassan S.-U., Aljohani N.R., Wasif M., Bibliometric perspective of learning analytics research landscape, Behavior and Information Technology, 37, pp. 941-957, (2018); Wang F., Breaking the silence: Examining process of cyber sextortion and victims’ coping strategies, International Review of Victimology, 31, (2024); Wang F., Topalli V., Understanding romance scammers through the lens of their victims: Qualitative modeling of risk and protective factors in the online context, American Journal of Criminal Justice, 49, pp. 145-181, (2024); Whitty M.T., The scammers persuasive techniques model: Development of a stage model to explain the online dating romance scam, British Journal of Criminology, 53, pp. 665-684, (2013); Whitty M.T., Anatomy of the online dating romance scam, Security Journal, 28, pp. 443-455, (2015); Whitty M.T., Do you love me? Psychological characteristics of romance scam victims, Cyberpsychology, Behavior, and Social Networking, 21, pp. 105-109, (2018); Whitty M.T., Buchanan T., The online romance scam: A serious cybercrime, CyberPsychology, Behavior, and Social Networking, 15, pp. 181-183, (2012); Whitty M.T., Buchanan T., The online dating romance scam: The psychological impact on victims–both financial and non-financial, Criminology and Criminal Justice, 16, pp. 176-194, (2016); Wisniewski P., Jia H., Wang N., Zheng S., Xu H., Rosson M.B., Carroll J.M., Resilience mitigates the negative effects of adolescent internet addiction and online risk exposure, Paper presented at the 33rd Annual ACM Conference on Human Factors in Computing Systems, (2015); Wisniewski P., Xu H., Rosson M.B., Perkins D.F., Carroll J.M., Dear Diary: Teens Reflect on Their Weekly Online Risk Experiences, Paper presented at the CHI ’16 Conference on Human Factors in Computing Systems, (2016); Wittes B., Poplin C., Jurecic Q., Spera C., Sextortion: Cybersecurity, Teenagers, and Remote Sexual Assault. Centre for Technology Innovation at Brookings, pp. 1-47, (2016); Wolak J., Finkelhor D., Walsh W., Treitman L., Sextortion of minors: Characteristics and dynamics, Journal of Adolescent Health, 62, pp. 72-79, (2018); Zeyzus Johns B.A., Casola A.R., Rea O., Skolnik N., Fidler S.K., Safe-Guarding Youth from Online Sexual Exploitation in the Digital Era: A Role for Primary Care, American Journal of Lifestyle Medicine, (2024)","F.M. Radebe; Department of Applied Information Systems, University of Johannesburg, Johannesburg, P.O. Box 524, South Africa; email: fmradebe@uj.ac.za","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20760760","","","","English","Soc. Sci.","Article","Final","","Scopus","2-s2.0-85215793265" -"de Abreu Gomes A.Z.; Lopes C.; da Silva R.F.P.B.","de Abreu Gomes, Amanda Zetzsche (59306157500); Lopes, Cristina (57191085912); da Silva, Rui Filipe Pereira Bertuzi (59305838200)","59306157500; 57191085912; 59305838200","Advancements in Bankruptcy Prediction Models and Bibliometric Analysis","2024","Proceedings of the European Conference on Research Methods in Business and Management Studies","23","1","","82","91","9","0","10.34190/ecrm.23.1.2428","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85202612376&doi=10.34190%2fecrm.23.1.2428&partnerID=40&md5=6fe4c8e17eb618a6c2e3c98ff9d28a42","CEOS.PP, ISCAP, Instituto Politécnico do Porto, Portugal","de Abreu Gomes A.Z., CEOS.PP, ISCAP, Instituto Politécnico do Porto, Portugal; Lopes C., CEOS.PP, ISCAP, Instituto Politécnico do Porto, Portugal; da Silva R.F.P.B., CEOS.PP, ISCAP, Instituto Politécnico do Porto, Portugal","Since the economic downturn of the 1930s, there has been a growing interest in predicting company bankruptcies. Though not a new topic, the prospect of business bankruptcy has gained increasing relevance due to globalisation. This study explores various methodologies employed in predicting bankruptcy. Preventing bankruptcies also bolsters economic stability by averting the adverse effects of insolvency on the community. Companies with a solid and flexible economic foundation are more likely to succeed. This article reviews existing literature, discusses prevalent predictive models, and presents a statistical analysis of bibliometric data associated with bankruptcy prediction. This work aims to answer the research question of identifying the trends over time in the econometric models used to predict bankruptcy. This article may be useful for finance and business students in providing an overview of the subject and for business managers to identify the key determinants of financial distress. Exploring the R package, Bibliometrix® demonstrates its efficacy as a powerful tool for science mapping. © 2024 Academic Conferences Limited. All rights reserved.","Bankruptcy prediction; Bibliometric analysis; Financial distress; Predictive models; Risk","","","","","","Fundação para a Ciência e a Tecnologia, FCT, (UIDB/05422/2020); Fundação para a Ciência e a Tecnologia, FCT","This work is financed by Portuguese national funds through FCT - Funda\u00E7\u00E3o para a Ci\u00EAncia e Tecnologia, under the project UIDB/05422/2020.","Adham S.A., Walker S.G., A Multivariate Gompertz-type Distribution, Journal of Applied Statistics, 28, 8, pp. 1051-1065, (2001); Aghelpour P., Mohammadi B., Biazar S.M., Kisi O., Sourmirinezhad Z., A Theoretical Approach for Forecasting Different Types of Drought Simultaneously, Using Entropy Theory and Machine-Learning Methods, ISPRS International Journal of Geo-Information, 9, 12, (2020); Akhundjanov S.B., Toda A.A., Is Gibrat's 'Economic Inequality' lognormal?, Empirical Economics, (2019); Almeida B.J.M., O Auditor e a Continuidade da Empresa - O Artigo 35ºdo Código das Sociedades Comerciais, Journal of Business and Legal Sciences, 16, pp. 69-93, (2010); Altman E.I., Financial Ratios, Discriminant Analysis and the Prediction of Corporate Bankruptcy, The Journal of Finance, 23, 4, pp. 589-609, (1968); Andersen P.K., Gill R.D., Cox's Regression Model for Counting Processes: A Large Sample Study, The Annals of Statistics, 10, 4, pp. 1100-1120, (1982); Argenti J., Corporate Planning and Corporate Collapse, Long Range Planning, 9, 6, pp. 12-17, (1976); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Barboza F., Kimura H., Altman E., Machine learning models and bankruptcy prediction, Expert Systems with Applications, 83, pp. 405-417, (2017); Barros G.C.O., Modelos de Previsão da Falência de Empresas - Aplicação Empírica ao Caso das Pequenas e Médias Empresas Portuguesas, pp. 10-15, (2008); Beaver W.H., Financial Ratios as Predictors of Failure, Journal of Accounting Research, 4, 3, pp. 71-111, (1966); Berg D., Bankruptcy Prediction by Generalized Additive Models, Applied Stochastic Models in Business and Industry, 23, 2, pp. 129-143, (2006); Burger C.J.C, A Tutorial on Support Vector Machines for Pattern Recognition, Data Mining and Knowledge Discovery, 2, 2, pp. 955-974, (1998); Chen M.-Y., Predicting Corporate Financial Distress Based on Integration of Decision Tree Classification and Logistic Regression, Expert Systems with Applications, 38, 9, pp. 11261-11272, (2011); Chen N., Ribeiro B., Vieira A., Chen A., Clustering and Visualization of Bankruptcy Trajectory Using Self-organizing Map, Expert Systems with Applications, 40, 1, pp. 385-393, (2013); Coad A., Frankish J., Roberts R.G., Storey D.J., Growth Paths and Survival chances: an Application of Gambler's Ruin Theory, Journal of Business Venturing, 28, 5, pp. 615-632, (2013); Cortes C., Vapnik V., Support-vector Networks, Machine Learning, 20, 3, pp. 273-297, (1995); Dimitras A.I., Slowinski R., Susmaga R., Zopounidis C., Business failure prediction using rough sets, European Journal of Operational Research, 114, 2, pp. 263-280, (1999); du Jardin P., Bankruptcy prediction using terminal failure processes, European Journal of Operational Research, 242, 1, pp. 286-303, (2015); Ferreira C.M.P., Modelo de previsão de insolvências no setor hoteleiro em Portugal, (2016); Fink A., Conducting research literature reviews: From the Internet to paper, (2005); Gibrat R., Les inégalités économiques: applications, aux inégalités des richesses, a la concentration des entreprises, aux populations des villes, aux statistiques des familles, etc.: d'une loi nouvelle la loi de l'effet proportionnel, (1931); Kaski S., Sinkkonen J., Peltonen J., Bankruptcy analysis with self-organizing maps in learning metrics, IEEE Transactions on Neural Networks, 12, 4, pp. 936-947, (2001); Korol T., Early warning models against bankruptcy risk for Central European and Latin American enterprises, Economic Modelling, 31, pp. 22-30, (2013); Laitinen E.K., Financial Ratios and Different Failure Processes, Journal of Business Finance & Accounting, 18, 5, pp. 649-673, (1991); Maganinho A.R.G., Estimação da Sobrevivência das Empresas Portuguesas nos Setores da Hotelaria e Restauração, Utilizando O Modelo de Cox, (2023); Odom M.D., Sharda R., A neural network model for bankruptcy prediction, 1990 IJCNN International Joint Conference on Neural Networks, (1990); Okoli C., A guide to conducting a standalone systematic literature review, Communications of the Association for Information Systems, 37, (2015); Paradi J.C., Asmild M., Simak P.C., Using DEA and Worst Practice DEA in Credit Risk Evaluation, Journal of Productivity Analysis, 21, 2, pp. 153-165, (2004); Peres C.J., A Eficácia dos Modelos de Previsão de Falência: Aplicação ao Caso das Sociedades Portuguesas, Dissertação, pp. 18-50, (2014); Platt H.D., Why Companies Fail: Strategies for detecting, avoiding, and Profiting from Bankruptcy, (1985); Roldan-Valadez E., Salazar-Ruiz S.Y., Ibarra-Contreras R., Rios C., Current concepts on bibliometrics: a brief review about impact factor, Eigenfactor score, CiteScore, SCImago Journal Rank, Source-Normalised Impact per Paper, H-index, and alternative metrics, Irish Journal of Medical Science (1971 -), 188, 3, pp. 939-951, (2018); Sousa J., Oliveira I., As variáveis de previsão da falência nas empresas portuguesas de vestuário, couro e produtos de couro, Revista de Gestão dos Países de Língua Portuguesa, 13, 1, pp. 62-73, (2014); Tam K.Y., Kiang M., Predicting Bank Failures: A Neural Network Approach, Applied Artificial Intelligence, 4, 4, pp. 265-282, (1990); White G., Sondhi A.C., Fried D., The Analysis and Use of Financial Statements, 2, pp. 1197-1210, (1998); Wilcox J.W., A gambler's ruin prediction of business failure using accounting data, Sloan Management Review, 12, pp. 1-10, (1971); Yang Z., You W., Ji G., Using partial least squares and support vector machines for bankruptcy prediction, Expert Systems with Applications, 38, 7, pp. 8336-8342, (2011); Wang Y., Wang S., A new fuzzy support vector machine to evaluate credit risk, IEEE Transactions on Fuzzy Systems, 13, 6, pp. 820-831, (2005)","","Azevedo A.I.","Academic Conferences and Publishing International Limited","","23rd European Conference on Research Methodology for Business and Management Studies, ECRM 2024","4 July 2024 through 5 July 2024","Porto","201641","20490968","978-191720404-0","","","English","Proc. Eur. Conf. Res. Meth. Bus. Manag. Stud.","Conference paper","Final","","Scopus","2-s2.0-85202612376" -"Nath S.; Thomson W.M.; Baker S.R.; Jamieson L.M.","Nath, Sonia (55574514700); Thomson, William Murray (7201689009); Baker, Sarah R. (7403308092); Jamieson, Lisa M. (35608634000)","55574514700; 7201689009; 7403308092; 35608634000","A bibliometric analysis of Community Dentistry and Oral Epidemiology: Fifty years of publications","2024","Community Dentistry and Oral Epidemiology","52","2","","171","180","9","6","10.1111/cdoe.12910","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173544436&doi=10.1111%2fcdoe.12910&partnerID=40&md5=6305437390bd699f281f39a04dc4408e","Australian Research Centre for Population Oral Health, The University of Adelaide, Adelaide, SA, Australia; Faculty of Dentistry, The University of Otago, Dunedin, New Zealand; School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom","Nath S., Australian Research Centre for Population Oral Health, The University of Adelaide, Adelaide, SA, Australia; Thomson W.M., Faculty of Dentistry, The University of Otago, Dunedin, New Zealand; Baker S.R., School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom; Jamieson L.M., Australian Research Centre for Population Oral Health, The University of Adelaide, Adelaide, SA, Australia","Objectives: In celebration of the journal's 50th anniversary, the aim of the study was to review the whole collection of Community Dentistry and Oral Epidemiology (CDOE) publications from 1973 to 2022 and provide a complete overview of the main publication characteristics. Methods: The study used bibliometric techniques such as performance and science mapping analysis of 3428 articles extracted from the Scopus database. The data were analysed using the ‘Bibliometrix’ package in R. The journal's scientific production was examined, along with the yearly citation count, the distribution of publications based on authors, the corresponding author's country and affiliation and citation count, citing source and keywords. Bibliometric network maps were constructed to determine the conceptual, intellectual and social collaborative structure over the past 50 years. The trending research topics and themes were identified. Results: The total number of articles and average citations has increased over the years. D Locker, AJ Spencer, A Sheiham and WM Thomson were the most frequently published authors, and PE Petersen, GD Slade and AI Ismail published papers with the highest citations. The most published countries were the United States, United Kingdom, Brazil and Canada, frequently engaging in collaborative efforts. The most common keywords used were ‘dental caries’, ‘oral epidemiology’ and ‘oral health’. The trending topics were healthcare and health disparities, social determinants of health, systematic review and health inequalities. Epidemiology, oral health and disparities were highly researched areas. Conclusion: This bibliometric study reviews CDOE's significant contribution to dental public health by identifying key research trends, themes, influential authors and collaborations. The findings provide insights into the need to increase publications from developing countries, improve gender diversity in authorship and broaden the scope of research themes. © 2023 The Authors. Community Dentistry and Oral Epidemiology published by John Wiley & Sons Ltd.","bibliometric analysis; network maps; oral epidemiology; performance analysis; scientometrics; community dentistry","Bibliometrics; Brazil; Canada; Community Dentistry; Humans; United Kingdom; United States; bibliometrics; Brazil; Canada; dental procedure; epidemiology; human; United Kingdom; United States","","","","","Australian University Librarians; Wiley - The University of Adelaide; National Health and Medical Research Council, NHMRC; University of Adelaide","Funding text 1: SN is supported by the Australian Government Research Training Program Scholarship. LMJ is supported by a National Health and Medical Research Council Senior Research Fellowship. Open access publishing facilitated by The University of Adelaide, as part of the Wiley ‐ The University of Adelaide agreement via the Council of Australian University Librarians. ; Funding text 2: SN is supported by the Australian Government Research Training Program Scholarship. LMJ is supported by a National Health and Medical Research Council Senior Research Fellowship. Open access publishing facilitated by The University of Adelaide, as part of the Wiley - The University of Adelaide agreement via the Council of Australian University Librarians.","Ninkov A., Frank J.R., Maggio L.A., Bibliometrics: methods for studying academic publishing, Perspect Med Educ, 11, 3, pp. 173-176, (2022); Aria M., Bibliometrix: an R-tool for comprehensive science mapping analysis, J Informet, 11, pp. 959-975, (2017); Khan A.S., Ur Rehman S., Ahmad S., AlMaimouni Y.K., Alzamil M.A.S., Dummer P.M.H., Five decades of the international endodontic journal: bibliometric overview 1967-2020, Int Endod J, 54, 10, pp. 1819-1839, (2021); Liu F.H., Yu C.H., Chang Y.C., Bibliometric analysis of articles published in journal of dental sciences from 2009 to 2020, J Dent Sci, 17, 1, pp. 642-646, (2022); Moraes R.R., Morel L.L., Correa M.B., Lima G.D.S., A bibliometric analysis of articles published in Brazilian dental journal over 30 years, Braz Dent J, 31, 1, pp. 10-18, (2020); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, J Bus Res, 133, pp. 285-296, (2021); 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Nath; Australian Research Centre of Population Oral Health, Adelaide Dental School, University of Adelaide, Adelaide, 5000, Australia; email: sonia.nath@adelaide.edu.au","","John Wiley and Sons Inc","","","","","","03015661","","CDOEA","37798876","English","Community Dent. Oral Epidemiol.","Article","Final","All Open Access; Green Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-85173544436" -"Singh M.; Nandan T.","Singh, Maneesha (58978204800); Nandan, Tanuj (55622747200)","58978204800; 55622747200","A bibliometric and visualization analysis of intertemporal choice: origins, growth and future research avenues","2024","Journal of Modelling in Management","19","5","","1644","1669","25","3","10.1108/JM2-07-2023-0157","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189905247&doi=10.1108%2fJM2-07-2023-0157&partnerID=40&md5=b58e32eb47e587e35dd70d8f0a6daf45","National Institute of Technology, Prayagraj, India; School of Management Studies, Motilal Nehru National Institute of Technology, Prayagraj, India; Government P G College Shillai, Himachal Pradesh University, Shillai, India","Singh M., National Institute of Technology, Prayagraj, India, Government P G College Shillai, Himachal Pradesh University, Shillai, India; Nandan T., School of Management Studies, Motilal Nehru National Institute of Technology, Prayagraj, India","Purpose: This study aims to conduct a bibliometric analysis on “intertemporal choice” behavior of individuals from journals in the Scopus database between 1957 and 2023. The research covered the data on the said topic since it first originated in the Scopus database and carried out performance analysis and content analysis of papers in the business management and finance disciplines. Design/methodology/approach: Bibliometric analysis, including science mapping and performance analysis, followed by content analysis of the papers of identified clusters, was conducted. Three clusters based on cocitation analysis and six themes (three major and three minor) were identified using the bibliometrix package in R studio. The content analysis of the papers in these clusters and themes have been discussed in this study, along with the thematic evolution of intertemporal choice research over the period of time, paving a way for future research studies. Findings: The review unpacks publication and citation trends of intertemporal choice behavior, the most significant authors, journals and papers along with the major clusters and themes of research based on cocitation and degree of centrality and relevance, respectively, i.e. discounting experiments and intertemporal choice, impulsivity, risk preference, time-inconsistent preference, etc. Originality/value: Over the past years, the research on “intertemporal choice” has flourished because of the increasing interest of researchers and scholars from different fields and the dynamic and pervasive nature of this topic. The well-developed and scattered body of knowledge on intertemporal choice has led to the need of applying a bibliometric analysis in the intertemporal choice literature. © 2024, Emerald Publishing Limited.","Bibliometric; Co-citation analysis; Hyperbolic discounting; Intertemporal choice; Thematic mapping","","","","","","","","Abdellaoui M., Attema A.E., Bleichrodt H., Intertemporal tradeoffs for gains and losses: an experimental measurement of discounted utility, The Economic Journal, 120, 545, pp. 845-866, (2010); Abdellaoui M., Bleichrodt H., l'Haridon O., Sign-dependence in intertemporal choice, Journal of Risk and Uncertainty, 47, 3, pp. 225-253, (2013); Acland D., Levy M.R., Naiveté, projection bias, and habit formation in gym attendance, Management Science, 61, 1, pp. 146-160, (2015); Ainslie G., Specious reward: a behavioral theory of impulsiveness and impulse control, Psychological Bulletin, 82, 4, (1975); Anchugina N., A simple framework for the axiomatization of exponential and quasi-hyperbolic discounting, Theory and Decision, 82, 2, pp. 185-210, (2017); Andersen S., Harrison G.W., Lau M.I., Rutstrom E.E., Eliciting risk and time preferences, Econometrica, 76, 3, pp. 583-618, (2008); Angerer S., Glatzle-Rutzler D., Lergetporer P., Sutter M., Donations, risk attitudes and time preferences: a study on altruism in primary school children, Journal of Economic Behavior and Organization, 115, pp. 67-74, (2015); Anthony Swaim J., Maloni M.J., Henley A., Campbell S., Motivational influences on supply manager environmental sustainability behavior, Supply Chain Management: An International Journal, 21, 3, pp. 305-320, (2016); Aria M., Misuraca M., Spano M., Mapping the evolution of social research and data science on 30 years of social indicators research, Social Indicators Research, 149, 3, pp. 803-831, (2020); Attema A.E., Brouwer W.B., Claxton K., Discounting in economic evaluations, PharmacoEconomics, 36, 7, pp. 745-758, (2018); Attema A.E., Bleichrodt H., Rohde K.I., Wakker P.P., Time-tradeoff sequences for analyzing discounting and time inconsistency, Management Science, 56, 11, pp. 2015-2030, (2010); Augenblick N., Niederle M., Sprenger C., Working over time: dynamic inconsistency in real effort tasks, The Quarterly Journal of Economics, 130, 3, pp. 1067-1115, (2015); Aymard S., Serra D., Do individuals use backward induction in dynamic optimization problems? 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Pick-Alony R., Liberman N., Trope Y., High level of construal and psychological distance reduce melioration, Journal of Behavioral Decision Making, 27, 4, pp. 291-300, (2014); Pritschmann R.K., Yurasek A.M., Yi R., A review of cross-commodity delay discounting research with relevance to addiction, Behavioural Processes, 186, (2021); Quach S., Barari M., Moudry D.V., Quach K., Service integration in omnichannel retailing and its impact on customer experience, Journal of Retailing and Consumer Services, 65, (2022); Rachlin H., Jones B.A., Social discounting and delay discounting, Journal of Behavioral Decision Making, 21, 1, pp. 29-43, (2008); Radicchi F., Fortunato S., Castellano C., Universality of citation distributions: toward an objective measure of scientific impact, Proceedings of the National Academy of Sciences, 105, 45, pp. 17268-17272, (2008); Rambaud S.C., Fernandez P.O., Oller I.M.P., A systematic review of the main anomalies in intertermporal choice, Journal of Behavioral and Experimental Economics, 104, (2023); Randhawa K., Wilden R., Hohberger J., A bibliometric review of open innovation: Setting a research agenda, Journal of Product Innovation Management, 33, 6, pp. 750-772, (2016); Rao R.S., Irwin J., Liu Z., Flying with a net, and without: Preventative devices and self-control, International Journal of Research in Marketing, 37, 3, pp. 521-543, (2020); Read D., Intrapersonal dilemmas, Human Relations, 54, 8, pp. 1093-1117, (2001); Read D., Is time-discounting hyperbolic or subadditive?, Journal of Risk and Uncertainty, 23, 1, pp. 5-32, (2001); Read D., Roelofsma P.H., Subadditive versus hyperbolic discounting: a comparison of choice and matching, Organizational Behavior and Human Decision Processes, 91, 2, pp. 140-153, (2003); Read D., Frederick S., Orsel B., Rahman J., Four score and seven years from now: the date/delay effect in temporal discounting, Management Science, 51, 9, pp. 1326-1335, (2005); Reyna V.F., Wilhelms E.A., The gist of delay of gratification: understanding and predicting problem behaviors, Journal of Behavioral Decision Making, 30, 2, pp. 610-625, (2017); Richards T.J., Green G.P., Environmental choices and hyperbolic discounting: an experimental analysis, Environmental and Resource Economics, 62, 1, pp. 83-103, (2015); Richards T.J., Hamilton S.F., Obesity and hyperbolic discounting: an experimental analysis, Journal of Agricultural and Resource Economics, pp. 181-198, (2012); Rohde K.I., Measuring decreasing and increasing impatience, Management Science, 65, 4, pp. 1700-1716, (2019); Ruggeri G., Orsi L., Corsi S., A bibliometric analysis of the scientific literature on Fairtrade labelling, International Journal of Consumer Studies, 43, 2, pp. 134-152, (2019); Samuelson P.A., A note on measurement of utility, The Review of Economic Studies, 4, 2, pp. 155-161, (1937); Schreiber P., Weber M., Time inconsistent preferences and the annuitization decision, Journal of Economic Behavior and Organization, 129, pp. 37-55, (2016); Schumacher H., Insurance, self-control, and contract flexibility, European Economic Review, 83, pp. 220-232, (2016); Shaddy F., Lee L., Price promotions cause impatience, Journal of Marketing Research, 57, 1, pp. 118-133, (2020); Shafir E., Thaler R.H., Invest now, drink later, spend never: on the mental accounting of delayed consumption, Journal of Economic Psychology, 27, 5, pp. 694-712, (2006); Shapiro J.M., Is there a daily discount rate? Evidence from the food stamp nutrition cycle, Journal of Public Economics, 89, 2-3, pp. 303-325, (2005); Shapiro M.S., Price P.C., Mitchell E., Carryover of domain-dependent risk preferences in a novel decision-making task, Judgment and Decision Making, 15, 6, pp. 1009-1023, (2020); Slawinski N., Bansal P., Short on time: Intertemporal tensions in business sustainability, Organization Science, 26, 2, pp. 531-549, (2015); Small H., Co‐citation in the scientific literature: a new measure of the relationship between two documents, Journal of the American Society for Information Science, 24, 4, pp. 265-269, (1973); Snyder H., Literature review as a research methodology: an overview and guidelines, Journal of Business Research, 104, pp. 333-339, (2019); Sternad D., Kennelly J.J., The sustainable executive: antecedents of managerial long-term orientation, Journal of Global Responsibility, 8, 2, pp. 179-195, (2017); Stockigt G., Schiebener J., Brand M., Providing sustainability information in shopping situations contributes to sustainable decision making: an empirical study with choice-based conjoint analyses, Journal of Retailing and Consumer Services, 43, pp. 188-199, (2018); Sun C., Potters J., Magnitude effect in intertemporal allocation tasks, Experimental Economics, 25, 2, pp. 593-623, (2022); Sutter C., Bruton G.D., Chen J., Entrepreneurship as a solution to extreme poverty: a review and future research directions, Journal of Business Venturing, 34, 1, pp. 197-214, (2019); Takahashi T., Theoretical frameworks for neuroeconomics of intertemporal choice, Journal of Neuroscience, Psychology, and Economics, 2, 2, (2009); Takahashi T., Han R., Nakamura F., Time discounting: psychophysics of intertemporal and probabilistic choices, Journal of Behavioral Economics and Finance, 5, pp. 10-14, (2012); Tang S., Purcal S., Zhang J., Life insurance and annuity demand under hyperbolic discounting, Risks, 6, 2, (2018); Tavares A.I., Time and risk preferences among the European seniors, relationship and associated factors, Journal of Business Economics, 92, 8, pp. 1283-1302, (2022); Turan A.R., Intentional time inconsistency, Theory and Decision, 86, 1, pp. 41-64, (2019); Tversky A., Slovic P., Kahneman D., The causes of preference reversal, The American Economic Review, pp. 204-217, (1990); Valenzuela L.M., Merigo J.M., Johnston W.J., Nicolas C., Jaramillo J.F., Thirty years of the journal of business and industrial marketing: a bibliometric analysis. Journal of business and industrial marketing, Journal of Business and Industrial Marketing, 32, 1, pp. 1-17, (2017); Velt H., Torkkeli L., Laine I., Entrepreneurial ecosystem research: bibliometric mapping of the domain, Journal of Business Ecosystems (JBE), 1, 2, pp. 43-83, (2020); Vlaev I., Wallace B., Wright N., Nicolle A., Dolan P., Dolan R., Other people’s money: the role of reciprocity and social uncertainty in decisions for others, Journal of Neuroscience, Psychology, and Economics, 10, 2-3, (2017); Wang M., Rieger M.O., Hens T., How time preferences differ: Evidence from 53 countries, Journal of Economic Psychology, 52, pp. 115-135, (2016); Wang S.L., Luo Y., Maksimov V., Sun J., Celly N., Achieving temporal ambidexterity in new ventures, Journal of Management Studies, 56, 4, pp. 788-822, (2019); Weber B.J., Tan W.P., Ambiguity aversion in a delay analogue of the Ellsberg paradox, Judgment and Decision Making, 7, 4, pp. 383-389, (2012); Wertenbroch K., Consumption self-control by rationing purchase quantities of virtue and vice, Marketing Science, 17, 4, pp. 317-337, (1998); Yang Y., Cao G., Optimal investment and endogenous payout strategy with time inconsistency, International Journal of Finance and Economics, 26, 1, pp. 707-723, (2021); Yi F., Yang P., Sheng H., Tracing the scientific outputs in the field of Ebola research based on publications in the web of science, BMC Research Notes, 9, 1, pp. 1-7, (2016); Yoon H., Impatience and time inconsistency in discounting models, Management Science, 66, 12, pp. 5850-5860, (2020); Young E.R., Generalized quasi-geometric discounting, Economics Letters, 96, 3, pp. 343-350, (2007); Yu D., Xu Z., Antucheviciene J., Bibliometric analysis of the journal of civil engineering and management between 2008 and 2018, Journal of Civil Engineering and Management, 25, 5, (2019); Zauberman G., Kim B.K., Malkoc S.A., Bettman J.R., Discounting time and time discounting: subjective time perception and intertemporal preferences, Journal of Marketing Research, 46, 4, pp. 543-556, (2009); Zhang L., Saving and retirement behavior under quasi-hyperbolic discounting, Journal of Economics, 109, 1, pp. 57-71, (2013); Zilker V., Pachur T., Does option complexity contribute to the framing effect, loss aversion, and delay discounting in younger and older adults?, Journal of Behavioral Decision Making, 34, 4, pp. 488-503, (2021); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","M. Singh; National Institute of Technology, Prayagraj, India; email: maneeshasingh79@gmail.com","","Emerald Publishing","","","","","","17465664","","","","English","J. Model. Manage.","Review","Final","","Scopus","2-s2.0-85189905247" -"Syahid A.; Aghayani B.","Syahid, Abdul (57395884400); Aghayani, Behnam (57213817680)","57395884400; 57213817680","ZOLTÁN DÖRNYEI’S IMPACT ON LANGUAGE ACQUISITION AND EDUCATION STUDIES: A SCOPUS-BASED BIBLIOMETRIC STUDY (1991-2023)","2024","LLT Journal: Journal on Language and Language Teaching","27","2","","818","843","25","0","10.24071/llt.v27i2.8058","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85202672312&doi=10.24071%2fllt.v27i2.8058&partnerID=40&md5=bcce08e71145ecdd5f28081b68d0aabd","Institut Agama Islam Negeri Palangka Raya, Indonesia; Iran","Syahid A., Institut Agama Islam Negeri Palangka Raya, Indonesia; Aghayani B., Iran","Previous literature reviews and bibliometric studies have paid much attention to the scientific outputs of Zoltán Dörnyei, a leading figure in the field of second language acquisition and education. However, little attention has been paid to his scholarly impact. This study aims to analyze all publications citing his 87 works in Scopus. Bibliometrix, a comprehensive bibliometric tool, was run to analyze 7,621 documents published in 1,970 sources by 9,226 authors of 2,652 institutions across 99 countries between 1991 and 2023. The analyses include the publication trend, research contributors, including authors, document elements including keywords, collaboration networks of research contributors, shared references, and frequently used keywords. Although most documents were written in English in the fields of social sciences as well as arts and humanities, his impact could be observed across other subject areas and languages. Further discussion elaborated on four major themes of the publications, including motivation, L2 motivational self-system, language learning, and positive psychology. This study could provide researchers and educators with valuable insights into understanding and improving language acquisition processes based on Dörnyei’s incalculable intellectual contribution. As this study focused on quantitative citation analysis, future research on how Dörnyei’s works were cited could provide deeper insights into his impact. © 2024, Sanata Dharma University. All rights reserved.","motivation language theory; publication and citation pattern; science mapping; scientometric portrait; Zoltán Dörnyei","","","","","","","","Ajzen I., Attitudes, personality and behaviour, (2005); Al-Hoorie A. H., Hiver P., Zoltán Dörnyei (1960–2022), Language Learning, 72, 4, pp. 896-898, (2022); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Chen C., Eugene Garfield’s scholarly impact: A scientometric review, Scientometrics, 114, 2, pp. 489-516, (2018); Claro J., Identification with external and internal referents: Integrativeness and the ideal L2 Self, Contemporary language motivation theory: 60 years since Gardner and Lambert (1959), pp. 233-261, (2019); de Bot K., A history of applied linguistics: From 1980 to the present, (2015); Deci E. L., Ryan R. M., Intrinsic motivation and self-determination in human behavior, (1985); Delpeuch A., Morris T., Huynh D., Weblate W., Mazzocchi S., Jacky J., Guidry T., Elebitzero E., Stephens O., Matsunami I., Sproat I., Santos S., Larsson A., Allanaaa A., Kushthedude K., Fauconnier S., Mishra E., Beaubien A., Magdinier M., Liu L., Giroud F., Ong J., Tacchelli F., Nordhoy A., Martinelli L., Kanye E., Saby M., Chandra L., OpenRefine/OpenRefine: OpenRefine v3.7.4, (2023); Dewaele J.-M., Preface to the third edition, Questionnaires in second language research: Construction, administration, and processing, pp. ix-xi, (2023); Dewaele J.-M., Dewaele L., Are foreign language learners’ enjoyment and anxiety specific to the teacher? An investigation into the dynamics of learners’ classroom emotions, Studies in Second Language Learning and Teaching, 10, 1, pp. 45-65, (2020); Dewaele J.-M., MacIntyre P. D., The two faces of Janus? Anxiety and enjoyment in the foreign language classroom, Studies in Second Language Learning and Teaching, 4, 2, pp. 237-274, (2014); Dewaele J.-M., MacIntyre P. D., Foreign language enjoyment and foreign language classroom anxiety: The right and left feet of the language learner, Positive psychology in SLA, pp. 215-236, (2016); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Dornyei Z., Conceptualizing motivation in foreign‐language learning, Language Learning, 40, 1, pp. 45-78, (1990); Dornyei Z., Motivation and motivating in the foreign language classroom, The Modern Language Journal, 78, 3, pp. 273-284, (1994); Dornyei Z., Motivation in second and foreign language learning, Language Teaching, 31, 3, pp. 117-135, (1998); Dornyei Z., The psychology of the language learner: Individual differences in second language acquisition, (2005); Dornyei Z., The L2 motivational self system, Motivation, language identity and the L2 self, pp. 9-42, (2009); Dornyei Z., From English language teaching to psycholinguistics: A story of three decades, Becoming and being an applied linguist, pp. 119-136, (2016); Dornyei Z., Preface, Contemporary language motivation theory: 60 years since Gardner and Lambert (1959), pp. xix-xxii, (2020); Dornyei Z., Csizer K., Some dynamics of language attitudes and motivation: Results of a longitudinal nationwide survey, Applied Linguistics, 23, 4, pp. 421-462, (2002); Dornyei Z., Csizer K., Nemeth N., Motivation, language attitudes and globalisation: A Hungarian perspective, (2006); Ellis R., The study of second language acquisition, (1994); Ellis R., The study of second language acquisition, (2008); Content—How Scopus works, (2023); Flynn C. J., Harris J., Motivational diversity among adult minority language learners: Are current theoretical constructs adequate?, Journal of Multilingual and Multicultural Development, 37, 4, pp. 371-384, (2016); Gardner R. C., Social psychology and second language learning: The role of attitudes and motivation, (1985); Gardner R. C., Lambert W. E., Attitudes and motivation in second-language learning, (1972); Glanzel W., The need for standards in bibliometric research and technology, Scientometrics, 35, 2, pp. 167-176, (1996); Gordin M. D., Scientific Babel: How science was done before and after global English, (2015); Hajar A., Karakus M., Obituary for Zoltán Dörnyei (1960–2022): A bibliometric mapping of his publications, Journal of Multilingual and Multicultural Development, pp. 1-28, (2023); Kessler M. M., Bibliographic coupling between scientific papers, American Documentation, 14, 1, pp. 10-25, (1963); Koo M., Lin S.-C., An analysis of reporting practices in the top 100 cited health and medicine-related bibliometric studies from 2019 to 2021 based on a proposed guideline, Heliyon, 9, 6, (2023); Limeranto J. T., Subekti A. S., Foreign language reading anxiety among Theology department students: Contributing factors and alleviating strategies, LLT Journal: A Journal on Language and Language Teaching, 24, 2, pp. 309-323, (2021); Linnenluecke M. K., Marrone M., Singh A. K., Conducting systematic literature reviews and bibliometric analyses, Australian Journal of Management, 45, 2, pp. 175-194, (2020); MacIntyre P. D., Mercer S., Introducing positive psychology to SLA, Studies in Second Language Learning and Teaching, 4, 2, pp. 153-172, (2014); Moral-Munoz J. A., Herrera-Viedma E., Santisteban-Espejo A., Cobo M. J., Software tools for conducting bibliometric analysis in science: An up-to-date review, El Profesional de La Información, 29, 1, pp. 1-29, (2020); Norton B., Identity and language learning: Extending the conversation, (2013); Oxford R., Foreword, Researching language learning motivation: A concise guide, pp. 1-4, (2022); Page M. J., McKenzie J. E., Bossuyt P. M., Boutron I., Hoffmann T. C., Mulrow C. D., Shamseer L., Tetzlaff J. M., Akl E. A., Brennan S. E., Chou R., Glanville J., Grimshaw J. M., Hrobjartsson A., Lalu M. M., Li T., Loder E. W., Mayo-Wilson E., McDonald S., Moher D., The PRISMA 2020 statement: An updated guideline for reporting systematic reviews, BMJ, 372, 71, pp. 1-20, (2021); Pandita R., Singh S., Self-citations, a trend prevalent across subject disciplines at the global level: An overview, Collection Building, 36, 3, pp. 115-126, (2017); Pease E. J., Lepp-Kaethler E., Wong M. S., In memoriam Zoltán Dörnyei (1960-2022), International Journal of Christianity and English Language Teaching, 9, 8, pp. 77-83, (2022); Scopus content coverage guide, (2023); Source details, (2023); Serenko A., Marrone M., Dumay J., Scientometric portraits of recognized scientists: A structured literature review, Scientometrics, 127, 8, pp. 4827-4846, (2022); Sugimoto C. R., Lariviere V., Measuring research: What everyone needs to know, (2018); Szomszor M., Pendlebury D. A., Adams J., How much is too much? The difference between research influence and self-citation excess, Scientometrics, 123, 2, pp. 1119-1147, (2020); Ushioda E., Dornyei Z., Motivation, language identities and the L2 self: A theoretical overview, Motivation, language identity, and the L2 self, pp. 9-42, (2009); van Eck N. J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Wilkinson M. D., Dumontier M., Aalbersberg Ij. J., Appleton G., Axton M., Baak A., Blomberg N., Boiten J.-W., da Silva Santos L. B., Bourne P. E., Bouwman J., Brookes A. J., Clark T., Crosas M., Dillo I., Dumon O., Edmunds S., Evelo C. T., Finkers R., Mons B., The FAIR guiding principles for scientific data management and stewardship, Scientific Data, 3, 1, (2016)","A. Syahid; Institut Agama Islam Negeri Palangka Raya, Indonesia; email: abdul.syahid@iain-palangkaraya.ac.id","","Sanata Dharma University","","","","","","14107201","","","","English","LLT. J.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85202672312" -"Li J.; Deacon C.; Keezer M.R.","Li, Jimmy (57226699683); Deacon, Charles (14007908600); Keezer, Mark Robert (18437280500)","57226699683; 14007908600; 18437280500","The performance of bibliometric analyses in the health sciences","2024","Current Medical Research and Opinion","40","1","","97","101","4","4","10.1080/03007995.2023.2281503","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85177423816&doi=10.1080%2f03007995.2023.2281503&partnerID=40&md5=4a96f50892e90711a568e7acf0e81b02","Neurology Division, Centre Hospitalier de l’Université de Sherbrooke (CHUS), Sherbrooke, QC, Canada; Centre de recherche du Centre Hospitalier de l’Université de Montréal (CRCHUM), Montreal, QC, Canada; Department of Neurosciences, Université de Montréal, Montreal, QC, Canada; School of Public Health, Université de Montréal, Montreal, QC, Canada; Neurology Division, Centre Hospitalier de l’Université de Montréal (CHUM), Montreal, QC, Canada","Li J., Neurology Division, Centre Hospitalier de l’Université de Sherbrooke (CHUS), Sherbrooke, QC, Canada, Centre de recherche du Centre Hospitalier de l’Université de Montréal (CRCHUM), Montreal, QC, Canada; Deacon C., Neurology Division, Centre Hospitalier de l’Université de Sherbrooke (CHUS), Sherbrooke, QC, Canada; Keezer M.R., Centre de recherche du Centre Hospitalier de l’Université de Montréal (CRCHUM), Montreal, QC, Canada, Department of Neurosciences, Université de Montréal, Montreal, QC, Canada, School of Public Health, Université de Montréal, Montreal, QC, Canada, Neurology Division, Centre Hospitalier de l’Université de Montréal (CHUM), Montreal, QC, Canada","A bibliometric analysis (BA) is a knowledge synthesis methodology aimed at quantitively summarizing large amounts of bibliometric data. We aimed to summarize the performance of BAs in the health sciences. We searched Scopus for BAs in the health sciences published prior to May 10, 2023. All identified studies were included. We performed a BA on these studies in two steps: performance analysis and science mapping. For the performance analysis, various indicators of scientific production were calculated using the bibliometrix R package. For the science mapping, VOSviewer was used to generate a co-authorship network and a keyword co-occurrence network. In total, 5,828 BAs were analyzed. Scientific production has exploded in the last years, with more than 1,500 BAs published in 2022 alone. Scientific impact (i.e. citations) has also been rising, although at a lesser pace. The mean number of citations per year per BA was 1.78. China was the most productive country, publishing more BAs than the nine other most productive countries combined. China paradoxically had a lower number of citations per publication compared with the nine other most productive countries. International collaborations were rare. Common BA themes included oncology, public health, neurosciences, mental health, artificial intelligence, and COVID-19. BAs are increasingly common in the health sciences, but their performance remains limited. More international collaborations and standardized guidelines could help improve their performance, notably the frequency at which they are cited. © 2023 Informa UK Limited, trading as Taylor & Francis Group.","bibliometrics; knowledge synthesis; Medicine; scientometrics; trends","Artificial Intelligence; Bibliometrics; Efficiency; Humans; Medicine; Publishing; artificial intelligence; bibliometrics; coronavirus disease 2019; human; knowledge; mental health; neuroscience; public health; Review; scientometrics; Scopus; artificial intelligence; bibliometrics; medicine; productivity; publishing","","","","","Centre Hospitalier de l’Université de Montréal; Fonds de Recherche Québec – Santé), academic institutions; UCB; TSC Alliance; Canadian Institutes of Health Research, IRSC; Fonds de Recherche du Québec - Santé, FRQS; Eisai Canada","JL is supported by the Fonds de Recherche Québec – Santé. CD reports no conflicts of interest. MRK reports unrestricted educational grants from UCB and Eisai, research grants for investigator-initiated studies from UCB and Eisai as well as from government entities (Canadian Institutes of Health Research, Fonds de Recherche Québec – Santé), academic institutions (Centre Hospitalier de l’Université de Montréal), and foundations (TD Bank, TSC Alliance, Savoy Foundation, Quebec Bio-Imaging Network). MRK’s salary is supported by the Fonds de Recherche Québec – Santé. ","Donthu N., Kumar S., Mukherjee D., Et al., How to conduct a bibliometric analysis: an overview and guidelines, J Bus Res, 133, pp. 285-296, (2021); Kokol P., Blazun Vosner H., Zavrsnik J., Application of bibliometrics in medicine: a historical bibliometrics analysis, Health Info Libr J, 38, 2, pp. 125-138, (2021); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, J Informetrics, 11, 4, pp. 959-975, (2017); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Chen C., CiteSpace II: detecting and visualizing emerging trends and transient patterns in scientific literature, J Am Soc Inf Sci, 57, 3, pp. 359-377, (2006); Falagas M.E., Pitsouni E.I., Malietzis G.A., Et al., Comparison of PubMed, scopus, web of science, and google scholar: strengths and weaknesses, FASEB J, 22, 2, pp. 338-342, (2008); Singh V.K., Singh P., Karmakar M., Et al., The journal coverage of web of science, scopus and dimensions: a comparative analysis, Scientometrics, 126, 6, pp. 5113-5142, (2021); R: a language and environment for statistical computing, (2021); Beall J., Beall's list of potential predatory journals and publishers, (2021)","M.R. Keezer; Centre Hospitalier de l’Université de Montréal, Montréal, 1000 rue Saint-Denis, H2X 0C1, Canada; email: mark.keezer@umontreal.ca","","Taylor and Francis Ltd.","","","","","","03007995","","CMROC","37938037","English","Curr. Med. Res. Opin.","Review","Final","","Scopus","2-s2.0-85177423816" -"Saeed H.; Martini N.D.; Scahill S.","Saeed, Hina (59032239900); Martini, Nataly Dominica (57196816776); Scahill, Shane (26538218500)","59032239900; 57196816776; 26538218500","Exploring telepharmacy: A bibliometric analysis of past research and future directions","2024","Research in Social and Administrative Pharmacy","20","9","","805","819","14","7","10.1016/j.sapharm.2024.04.017","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192204281&doi=10.1016%2fj.sapharm.2024.04.017&partnerID=40&md5=babf67ebcb13f6d720a739b4e390196b","School of Pharmacy, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand","Saeed H., School of Pharmacy, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand; Martini N.D., School of Pharmacy, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand; Scahill S., School of Pharmacy, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand","This bibliometric review analyzes the evolution of telepharmacy research, significantly amplified by the COVID-19 pandemic. By employing bibliometric analysis, the study aims to provide a comprehensive overview of the current state and emerging trends in telepharmacy. This approach helps in identifying key areas of growth, predominant themes, and potential gaps in the literature. Utilizing data from 330 papers (1981–2023) sourced from Scopus and analyzed with Bibliometrix™, this study applies both performance analysis and science mapping methods to examine the telepharmacy literature. The findings reveal a consistent growth in telepharmacy research, with an 8.07 % average annual growth rate. Performance analysis highlights key authors, influential works, and leading journals and countries in the field. Document co-citation analysis identifies four developmental phases of telepharmacy: emergence, take-off, expansion, and future trajectory by uncovering the intellectual structure of the field. Co-words analysis elucidates evolving conceptual structures and significant subfields over time. These findings serve to inform practitioners and researchers about the evolving landscape of telepharmacy, guiding future research and practice in this increasingly important field. © 2024 The Authors","Bibliometric analysis; Co-citation analysis; Co-words analysis; Performance analysis; Science mapping; Telepharmacy","Bibliometrics; COVID-19; Humans; Telemedicine; bibliometrics; coronavirus disease 2019; human; telemedicine","","","","","","","Angaran D.M., Telemedicine and telepharmacy: current status and future implications, Am J Health Syst Pharm, 56, pp. 1405-1426, (1999); Dupuits F.M.H.M., The effects of the internet on pharmaceutical consumers and providers, Dis Manag Health Outcome, 10, pp. 679-691, (2002); Awan J., Tele-Patient: audiovisual education in the pharmacy, Am Pharm, NS21, (1981); Abou-Shaaban R.R.A., Niazy E.M., Telemedicine and telepharmaceutical services: a model to improve maldistribution of medical resources between regions & urban/rural sectors in the kingdom of Saudi Arabia, Geojournal, 25, pp. 401-412, (1991); Landis N.T., APhA sets policy on telepharmacy, DTC ads, unions, Am J Health Syst Pharm, 56, pp. 706-707, (1999); Peterson C.D., Anderson J.H., The North Dakota telepharmacy project: restoring and retaining pharmacy services in rural communities, J Pharm Technol, 20, pp. 28-39, (2004); Koonin L.M., Hoots B., Tsang C.A., Et al., Trends in the use of telehealth during the emergence of the COVID-19 pandemic - United States, January-March 2020, MMWR (Morb Mortal Wkly Rep), 69, pp. 1595-1599, (2020); Baldoni S., Amenta F., Ricci G., Telepharmacy services: present status and future perspectives: a review, Medicina, 55, (2019); Sabanovic S., Veladzic A., Ramic I., Mamatnazarova N., Review of application of telepharmacy solutions in the practice, 9th Mediterranean Conference on Embedded Computing, MECO, (2020); Margret Chandira R., Palanisamy P., Jaykar B., Et al., Telepharmacy - a review, J. 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Med., 6, (2019); Leon A., Caceres C., Fernandez E., Et al., A new multidisciplinary home care telemedicine system to monitor stable chronic human immunodeficiency virus-infected patients: a randomized study, PLoS One, 6, (2011); Koster E.S., Philbert D., Bouvy M.L., Impact of the COVID-19 epidemic on the provision of pharmaceutical care in community pharmacies, Res Soc Adm Pharm, 17, pp. 2002-2004, (2021); Li H., Zheng S., Liu F., Liu W., Zhao R., Fighting against COVID-19: innovative strategies for clinical pharmacists, Res Soc Adm Pharm, 17, pp. 1813-1818, (2021); Liu S., Luo P., Tang M., Et al., Providing pharmacy services during the coronavirus pandemic, Int J Clin Pharm, 42, pp. 299-304, (2020); Allan J., Nott S., Chambers B., Et al., A stepped wedge trial of efficacy and scalability of a virtual clinical pharmacy service (VCPS) in rural and remote NSW health facilities, BMC Health Serv Res, 20, (2020); Allan J., Webster E., Chambers B., Nott S., “This is streets ahead of what we used to do”: staff perceptions of virtual clinical pharmacy services in rural and remote Australian hospitals, BMC Health Serv Res, 21, (2021); 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Pract.-Granada., 20, (2022)","H. Saeed; School of Pharmacy, The University of Auckland, Auckland, Private Bag 92019, 1142, New Zealand; email: hina.saeed@auckland.ac.nz","","Elsevier Inc.","","","","","","15517411","","","38714397","English","Res. Soc. Adm. Pharm.","Review","Final","All Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-85192204281" -"Moradi E.","Moradi, Erfan (57215671451)","57215671451","Mapping of Journal of Hospitality and Tourism Insights themes: a retrospective overview","2024","Journal of Hospitality and Tourism Insights","7","2","","1211","1237","26","13","10.1108/JHTI-12-2022-0638","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85159296806&doi=10.1108%2fJHTI-12-2022-0638&partnerID=40&md5=1713cb697c008f116fb5fb6bd2620c18","Department of Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran","Moradi E., Department of Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran","Purpose: Recognising the literature of a field is vital for advancement in that field. Yet, there has not been a systematic analysis of recent publications published in the Journal of Hospitality and Tourism Insights (JHTI). Therefore, this research aims to do a bibliometric analysis of articles published in JHTI during the previous five years. Design/methodology/approach: This study used bibliometric techniques and indicators to analyse JHTI publications from 2018 to 2022. The data utilised in the study were obtained from Scopus and subsequently subjected to analysis through the Bibliometrix software. Findings: The findings show good collaboration between the production components (country, institution and author) in JHTI. The co-occurrence analysis of keywords comprises five clusters; the co-citation analysis comprises six; and a group of articles connected with psychological aspects and areas such as motivation, attitude, customer engagement, place attachment and behavioural intention was the most remarkable cluster. Sharing economy, destination marketing, destination image and some, to an extent, social media and revenue management are just a few of the niche themes that have the potential to come up. Research limitations/implications: This study will be helpful as a roadmap for researchers in different fields who are interested in such studies, as well as for editorial board members and those who work in JHTI. Practical implications: Scholars and practitioners may benefit the most from this research by obtaining insight into the development of JHTI's research and the areas of the hospitality and tourism industries that need more study. Originality/value: The current study is both necessary and valuable because it is the first to provide insight into the effectiveness and intellectual framework of the hospitality and tourism literature selected by the JHTI. © 2023, Emerald Publishing Limited.","Bibliometric analysis; Hospitality and tourism; Intellectual structure; Journal of Hospitality and Tourism Insights; Science mapping; Scopus","","","","","","","","Agyeiwaah E., Dayour F., Zhou J.Y., How does employee commitment impact customers' attitudinal loyalty?, Journal of Hospitality and Tourism Insights, 5, 2, pp. 350-376, (2022); Ahn J., Kwon J., CSR perception and revisit intention: the roles of trust and commitment, Journal of Hospitality and Tourism Insights, 3, 5, pp. 607-623, (2020); Ajzen I., From intentions to actions: a theory of planned behavior, Action-control: from Cognition to Behavior, pp. 11-39, (1985); Ajzen I., The theory of planned behavior, Organizational Behavior and Human Decision Processes, 50, 2, pp. 179-211, (1991); Ajzen I., Fishbein M., Understanding Attitudes and Predicting Social Behaviour, (1980); Ali F., Kumar S., Sureka R., Gaur V., Cobanoglu C., The Journal of Hospitality and Tourism Technology (JHTT): a retrospective review using bibliometric analysis, Journal of Hospitality and Tourism Technology, 13, 5, pp. 781-800, (2022); Amoako G.K., Neequaye E.K., Kutu-Adu S.G., Caesar L.D., Ofori K.S., Relationship marketing and customer satisfaction in the Ghanaian hospitality industry: an empirical examination of trust and commitment, Journal of Hospitality and Tourism Insights, 2, 4, pp. 326-340, (2019); Amoako G.K., Caesar L.D., Dzogbenuku R.K., Bonsu G.A., Service recovery performance and repurchase intentions: the mediation effect of service quality at KFC, Journal of Hospitality and Tourism Insights, (2021); Ampong G.O.A., Abubakari A., Mohammed M., Appaw-Agbola E.T., Addae J.A., Ofori K.S., Exploring customer loyalty following service recovery: a replication study in the Ghanaian hotel industry, Journal of Hospitality and Tourism Insights, 4, 5, pp. 639-657, (2021); Ampountolas A., Shaw G., James S., The role of social media as a distribution channel for promoting pricing strategies, Journal of Hospitality and Tourism Insights, 2, 1, pp. 75-91, (2019); Anderson J.C., Gerbing D.W., Structural equation modeling in practice: a review and recommended two-step approach, Psychological Bulletin, 103, 3, (1988); Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aria M., Cuccurullo C., Science mapping analysis with bibliometrix R-package: an example, (2020); Atasoy B., Turkay O., Sengul S., Strategic responses of chain hotels to COVID-19 from a situational crisis communication theory perspective, Journal of Hospitality and Tourism Insights, 5, 5, pp. 1118-1136, (2022); Baggio R., Network science and tourism – the state of the art, Tourism Review, 72, 1, pp. 120-131, (2017); Bogan E., Dedeoglu B.B., The effects of hotel employees' CSR perceptions on trust in organization: moderating role of employees' self-experienced CSR perceptions, Journal of Hospitality and Tourism Insights, 2, 4, pp. 391-408, (2019); Baker H.K., Kumar S., Pattnaik D., Research constituents, intellectual structure, and collaboration pattern in the Journal of Forecasting: a bibliometric analysis, Journal of Forecasting, 40, 4, pp. 577-602, (2020); Baloglu S., McCleary K.W., A model of destination image formation, Annals of Tourism Research, 26, 4, pp. 868-897, (1999); Barbe D., Pennington-Gray L., Using situational crisis communication theory to understand Orlando hotels' Twitter response to three crises in the summer of 2016, Journal of Hospitality and Tourism Insights, 1, 3, pp. 258-275, (2018); Bastidas-Manzano A.B., Sanchez-Fernandez J., Casado-Aranda L.A., The past, present, and future of smart tourism destinations: a bibliometric analysis, Journal of Hospitality & Tourism Research, 45, 3, pp. 529-552, (2021); Beerli A., Martin J.D., Factors influencing destination image, Annals of Tourism Research, 31, 3, pp. 657-681, (2004); Benckendorff P., Zehrer A., A network analysis of tourism research, Annals of Tourism Research, 43, pp. 121-149, (2013); Casadei P., Bloom M., Camerani R., Masucci M., Siepel J., Ospina J.V., Mapping the state of the art of creative cluster research: a bibliometric and thematic analysis, European Planning Studies, pp. 1-21, (2023); Celik S., Dedeoglu B.B., Psychological factors affecting the behavioral intention of the tourist visiting Southeastern Anatolia, Journal of Hospitality and Tourism Insights, 2, 4, pp. 425-450, (2019); Chin W.W., Commentary: issues and opinion on structural equation modeling, MIS Quarterly, pp. vii-xvi, (1998); Crompton J.L., Motivations for pleasure vacation, Annals of Tourism Research, 6, 4, pp. 408-424, (1979); Cuccurullo C., Aria M., Sarto F., Foundations and trends in performance management. 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Moradi; Department of Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran; email: erfan.moradi@modares.ac.ir","","Emerald Publishing","","","","","","25149792","","","","English","J. Hosp. Tour. Insight.","Article","Final","","Scopus","2-s2.0-85159296806" -"Zafar M.B.; Abu-Hussin M.F.","Zafar, Muhammad Bilal (57224669951); Abu-Hussin, Mohd Fauzi (58809108900)","57224669951; 58809108900","Halal purchasing decisions and consumer behavior: a multi­ method review","2025","Journal of Islamic Marketing","","","","","","","1","10.1108/JIMA-08-2024-0365","https://www.scopus.com/inward/record.uri?eid=2-s2.0-86000195386&doi=10.1108%2fJIMA-08-2024-0365&partnerID=40&md5=932d1c07226ec340c891b56bfacb8a26","Faculty of Social Sciences and Humanities, Universiti Teknologi Malaysia, Johor Bahru, Malaysia; School of Islamic Economics, Banking and Finance, Minhaj University Lahore, Lahore, Pakistan","Zafar M.B., Faculty of Social Sciences and Humanities, Universiti Teknologi Malaysia, Johor Bahru, Malaysia, School of Islamic Economics, Banking and Finance, Minhaj University Lahore, Lahore, Pakistan; Abu-Hussin M.F., Faculty of Social Sciences and Humanities, Universiti Teknologi Malaysia, Johor Bahru, Malaysia","Purpose: The purpose of this study is to provide a comprehensive exploration of academic research on halal purchasing decisions and consumer behavior by integrating bibliometric and systematic review methodologies. Design/methodology/approach: This study uses a multi-method approach, combining bibliometric and systematic review methodologies, to comprehensively analyze the domain of halal purchasing decisions and consumer behavior. A data set of 184 articles published between 2007 and 2024 was sourced from the Scopus database. The bibliometric analysis was conducted using Bibliometrix in R, facilitating performance analysis, science mapping and network analysis to explore key authors, affiliations, collaborations and thematic trends. Additionally, the systematic review examined the limitations and future research areas discussed in prior studies, providing the basis for formulating potential research questions to address identified gaps. Findings: The study identifies significant contributions within the domain of halal purchasing decisions and consumer behavior, emphasizing the critical roles of religiosity, trust and halal certification as dominant themes. Bibliometric analysis reveals key authors, influential publications and collaborative networks, highlighting Malaysia as a central hub for research in this field. Additionally, the analysis underscores the intellectual structure and thematic evolution, identifying underexplored areas such as non-Muslim perspectives, emerging halal industries and geographic diversity. The systematic review complements these insights by addressing recurring methodological and theoretical limitations, offering targeted recommendations for future research. Originality/value: This research uniquely combines bibliometric and systematic review methodologies to provide a comprehensive review of the halal consumer behavior literature, identifying limitations and gaps in prior studies and proposing actionable areas for future research. © 2025, Emerald Publishing Limited.","Bibliometric analysis; Consumer behavior; Halal market; Halal purchasing decisions; Systematic review","","","","","","Research Management Centre, Universiti Teknologi Malaysia, RMC, (Q.J130000.21A2.07E49); Research Management Centre, Universiti Teknologi Malaysia, RMC; Universiti Teknologi Malaysia, UTM, (Q.J130000.3053.05M03); Universiti Teknologi Malaysia, UTM","This research was supported by the Research Management Center, Universiti Teknologi Malaysia under PDRU grant Q.J130000.21A2.07E49 and MG UTM grant Q.J130000.3053.05M03.","Ab Talib M.S., Pang L.L., Ngah A.H., The role of government in promoting halal logistics: a systematic literature review, Journal of Islamic Marketing, 12, 9, pp. 1682-1708, (2020); 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Malaysian Journal of Consumer and Family Economics, 25, pp. 172-186, (2020)","M.B. Zafar; Faculty of Social Sciences and Humanities, Universiti Teknologi Malaysia, Johor Bahru, Malaysia; email: bilalezafar@gmail.com","","Emerald Publishing","","","","","","17590833","","","","English","J. Islam. Mark.","Review","Article in press","","Scopus","2-s2.0-86000195386" -"Hernández-González V.; Conesa-Milian E.; Jové-Deltell C.; Pano-Rodríguez Á.; Legaz-Arrese A.; Reverter-Masia J.","Hernández-González, Vicenç (55777812000); Conesa-Milian, Enric (58555439000); Jové-Deltell, Carme (55830044800); Pano-Rodríguez, Álvaro (57208438126); Legaz-Arrese, Alejandro (12785167800); Reverter-Masia, Joaquin (16022966600)","55777812000; 58555439000; 55830044800; 57208438126; 12785167800; 16022966600","Global research trends on cardiac troponin and physical activity among pediatric populations: a bibliometric analysis and science mapping study","2024","Frontiers in Pediatrics","12","","1285794","","","","1","10.3389/fped.2024.1285794","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85185253024&doi=10.3389%2ffped.2024.1285794&partnerID=40&md5=1ee1234021d6a85d948dc455edc6731f","Human Movement Research Group (RGHM), University of Lleida, Lleida, Spain; Physical Education and Sport Section, University of Lleida, Lleida, Spain; Section of Physical Education and Sports, Faculty of Health and Sport Sciences, University of Zaragoza, Zaragoza, Spain","Hernández-González V., Human Movement Research Group (RGHM), University of Lleida, Lleida, Spain, Physical Education and Sport Section, University of Lleida, Lleida, Spain; Conesa-Milian E., Human Movement Research Group (RGHM), University of Lleida, Lleida, Spain, Physical Education and Sport Section, University of Lleida, Lleida, Spain; Jové-Deltell C., Human Movement Research Group (RGHM), University of Lleida, Lleida, Spain, Physical Education and Sport Section, University of Lleida, Lleida, Spain; Pano-Rodríguez Á., Human Movement Research Group (RGHM), University of Lleida, Lleida, Spain, Physical Education and Sport Section, University of Lleida, Lleida, Spain; Legaz-Arrese A., Section of Physical Education and Sports, Faculty of Health and Sport Sciences, University of Zaragoza, Zaragoza, Spain; Reverter-Masia J., Human Movement Research Group (RGHM), University of Lleida, Lleida, Spain, Physical Education and Sport Section, University of Lleida, Lleida, Spain","Background: Cardiac troponin (cTn) is a reliable marker for evaluating myocardial damage. cTn is a very specific protein involved in myocardial injury, and it is a key factor in the diagnosis of coronary syndromes. Bibliometric analysis was applied in the present work, with the main goal of evaluating global research on the topic of cardiac troponin in pediatric populations. Methods: Publications about cardiac troponin and physical activity in pediatric populations were retrieved from the Social Sciences Citation Index (SSCI) and the Science Citation Index Expanded (SCIE) of the Web of Science Core Collection, and they were then analyzed. The study was able to identify the key bibliometric indicators, such as publications, keywords, authors, countries, institutions, and journals. For the analysis, VOSviewer, R-based Bibliometrix (4.2.2), and MapChart were used. Results: Initially, 98 documents were identified; however, once inclusion and exclusion criteria were applied, the number of documents decreased to 88. The search yielded 79 original research articles and 9 reviews, almost all of which were published in the past 2 decades. The total number of citations (Nc) of the retrieved publications was 1,468, and the average number of citations per article (Na) was 16.68. In general, 508 authors were found to have participated in research about troponin; they were associated with 256 institutions, and their work was published in 65 different journals from around the world. The authors hailed from 30 countries and/or regions. The year 2022 was the most productive year for the publication of the selected documents. The bibliometric analysis provided information regarding levels of cooperation among authors and institutions. In fact, China, the United States, and England were the most productive nations, and the journal with the greatest number of publications on the topic was Pediatric Cardiology. Summary: The number of publications and the trend line show that research on this topic has not yet reached a stage of maturity. There are referent investigators, countries, and institutions that have laid the foundations for subsequent studies on the analyzed topic. 2024 Hernández-González, Conesa-Milian, Jové-Deltell, Pano-Rodriguez, Legaz-Arrese and Reverter-Masia.","bibliometrics; cardiac troponin; network analysis; pediatric; productivity; sports science; Web of Science","troponin; Article; bibliometrics; China; England; human; network analysis; pediatric cardiology; physical activity; United States","","","","","State Plan for R+D+I 2020, (PID2020-117932RB-I00); State Program for Research, Development and InnovationOriented","This research was funded by the State Program for Research, Development and InnovationOriented to the Challenges of Society, within the framework of the State Plan for R+D+I 2020–2024. The title of the project is: “Evaluación de diversos parámetros de salud y niveles de actividad física enla escuela primaria y secundaria”, grant number PID2020-117932RB-I00. The consolidated research group is the Human Movement Generalitat de Catalunya, 021 SGR 01619. ","Cordero A., Masia M.D., Galve E., Ejercicio físico y salud, Rev esp Cardiol, 67, 9, pp. 748-753, (2014); Legaz-Arrese A., Lopez-Laval I., George K., Puente-Lanzarote J.J., Mayolas-Pi C., Serrano-Ostariz E., Et al., Impact of an endurance training program on exercise-induced cardiac biomarker release, Am J Physio-Heart Circul Physiol, 308, 8, pp. 913-920, (2015); Cirer-Sastre R., Legaz-Arrese A., Corbi F., Lopez-Laval I., Puente-Lanzarote J., Hernandez-Gonzalez V., Et al., Effect of training load on post-exercise cardiac troponin T elevations in young soccer players, Int J Environ Res Public Health, 16, 23, (2019); Legaz-Arrese A., Lopez-Laval I., George K., Puente-Lanzarote J.J., Moliner-Urdiales D., Ayala-Tajuelo V.J., Et al., Individual variability in cardiac biomarker release after 30min of high-intensity rowing in elite and amateur athletes, Appl Physiol Nutr Metab, 40, 9, pp. 951-958, (2015); Cirer-Sastre R., Legaz-Arrese A., Corbi F., Lopez-Laval I., George K., Reverter-Masia J., Influence of maturational status in the exercise-induced release of cardiac troponin T in healthy young swimmers, J Sci Med Sport, 24, 2, pp. 116-121, (2021); Legaz-Arrese A., Lopez-Laval I., George K., Puente-Lanzarote J., Castellar-Otin C., Reverter-Masia J., Et al., Individual variability of high-sensitivity cardiac troponin levels after aerobic exercise is not mediated by exercise mode, Biomarkers, 20, 4, pp. 219-224, (2015); Lopez-Laval I., Legaz-Arrese A., George K., Serveto-Galindo O., Gonzalez-Rave J.M., Reverter-Masia J., Et al., Cardiac troponin I release after a basketball match in elite, amateur and junior players, Clin Chem Lab Med, 54, 2, pp. 333-338, (2016); Sribhen K., Piyophirapong S., Wannasilp N., Cardiac troponin T concentrations in healthy adolescents, Clin Chim Acta, 411, 19-20, pp. 1542-1543, (2010); Bohn M.K., Higgins V., Kavsak P., Hoffman B., Adeli K., High-sensitivity generation 5 cardiac troponin T sex- and age-specific 99th percentiles in the CALIPER cohort of healthy children and adolescents, Clin Chem, 65, 4, pp. 589-591, (2019); Sigurdardottir F.D., Lyngbakken M.N., Holmen O.L., Dalen H., Hveem K., Rosjo H., Et al., Relative prognostic value of cardiac troponin I and C-reactive protein in the general population (from the nord-trøndelag health [HUNT] study), Am J Cardiol, 121, 8, pp. 949-955, (2018); 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Dis, 9, (2022); Kiess A., Green J., Willenberg A., Ceglarek U., Dahnert I., Jurkutat A., Et al., Age-dependent reference values for hs-troponin T and NT-proBNP and determining factors in a cohort of healthy children (the LIFE child study), Pediatr Cardiol, 43, pp. 1071-1083, (2022); Clerico A., Aimo A., Cantinotti A., High-sensitivity cardiac troponins in pediatric population, Clin Chem Lab Med, 60, 1, pp. 18-32, (2022); Bjornar T., Bjornestad S., Chen W., Nyre L., Word cloud visualisation of locative information, J Location Based Services, 9, 4, pp. 254-272, (2015); Mulay P., Joshi R., Chaudhari A., Distributed incremental clustering algorithms: a bibliometric and word-cloud review analysis, Sci Technol Libr, 39, pp. 289-306, (2020); Tugce Guler A., Waaijer C.J.F., Palmblad M., Scientific workflows for bibliometrics, Scientometrics, 107, pp. 385-398, (2016); Patil R.R., Kumar S., Rani R., Agrawal P., Pippal S.K., A bibliometric and word cloud analysis on the role of the internet of things in agricultural plant disease detection, Appl. 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Salud Pública, 22, pp. 246-252, (2020); Chen K., Zhang Y., Fu X., International research collaboration: an emerging domain of innovation studies?, Res Policy, 48, 1, pp. 149-168, (2019); Adams J., The fourth age of research, Nature, 497, 7451, pp. 557-560, (2013); Desai N., Veras L., Gosain A., Using bradford’s law of scattering to identify the core journals of pediatric surgery, J Surg Res, 229, pp. 90-95, (2018); Bradford S.C., Sources of information on specific subjects, Engineering, 137, pp. 85-86, (1934); Highhouse S., Zickar M.J., Melick S.R., Prestige and relevance of the scholarly journals: impressions of SIOP members, Ind Organ Psychol, 13, 3, pp. 273-290, (2020); Torres-Salinas D., Cabezas-Clavijo A., (2013); Derntl M., Basic of research paper writing and publishing, Int J Technol Enhanc Learn, 6, pp. 105-123, (2014); Caceres Castellanos G., La importancia de publicar los resultados de investigación, Rev Fac Ing, 23, pp. 7-8, (2014); Tian Y., Nie J.L., Juang C.Y., George K.P., The kinetics of highly sensitive cardiac troponin T release after prolonged treadmill exercise in adolescent and adult athletes, J Appl Physio, 113, 3, pp. 418-425, (2012); Van der Zwaard S., Arie-Willem de Leeuw L., Meerhoff A., Bodine S.C., Knobbe A., Article with impact: insights into 10 years of research with machine learning, J Appl Physiology, 129, pp. 967-979, (2020)","","","Frontiers Media SA","","","","","","22962360","","","","English","Front. Pediatr.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85185253024" -"Suparman; Sukoco I.; Hermanto B.; Rivani","Suparman (59719001200); Sukoco, Iwan (57195494150); Hermanto, Bambang (57214225827); Rivani (59010035900)","59719001200; 57195494150; 57214225827; 59010035900","Destination Image and Trust in Tourism: A Comprehensive Bibliometric Exploration using R-Tool Bibliometrix","2024","Journal of Logistics, Informatics and Service Science","11","8","","438","454","16","1","10.33168/JLISS.2024.0825","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105001618011&doi=10.33168%2fJLISS.2024.0825&partnerID=40&md5=87d88e4eaef4d8ca89d3128319f6846c","Business Administration, Department of Social and Political Science, Universitas Padjadjaran, Bandung, Indonesia","Suparman, Business Administration, Department of Social and Political Science, Universitas Padjadjaran, Bandung, Indonesia; Sukoco I., Business Administration, Department of Social and Political Science, Universitas Padjadjaran, Bandung, Indonesia; Hermanto B., Business Administration, Department of Social and Political Science, Universitas Padjadjaran, Bandung, Indonesia; Rivani, Business Administration, Department of Social and Political Science, Universitas Padjadjaran, Bandung, Indonesia","Understanding the relationship between destination image and destination trust is crucial for sustainable tourism development. This bibliometric study aims to analyze the research trends and future directions in this field by examining 330 publications from the Scopus database between 2006 and 2023. Utilizing the R-Tool Bibliometrix, the authors conduct performance analysis and science mapping techniques to identify significant sources, authors, countries, affiliations, and influential articles. The findings reveal a steady but declining growth in citations related to destination image and trust, highlighting the need for further research. Thematic maps and trend analysis indicate an emphasis on emotional responses and the influence of social media, particularly among younger generations, in shaping destination choices. The study suggests expanding the destination image literature to incorporate emotional factors and leveraging social media insights to foster authentic tourist experiences. By providing a comprehensive bibliometric analysis, this research offers valuable insights for tourism researchers, practitioners, and policymakers to strategically manage destination image and build trust among visitors. © 2024, Success Culture Press. All rights reserved.","Bibliometric; Destination Image; Destination Trust; Tourism","","","","","","","","Abbasi A. Z., Tsiotsou R. H., Hussain K., Rather R. A., Ting D. H., Investigating the impact of social media images’ value, consumer engagement, and involvement on eWOM of a tourism destination: A transmittal mediation approach, Journal of Retailing and Consumer Services, 71, (2023); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aria M., Cuccurullo C., D'aniello L., Misuraca M., Spano M., Thematic Analysis as a New Culturomic Tool: The Social Media Coverage on COVID-19 Pandemic in Italy, Sustainability (Switzerland), 14, 6, (2022); Aria M., Misuraca M., Spano M., Mapping the Evolution of Social Research and Data Science on 30 Years of Social Indicators Research, Social Indicators Research, 149, 3, pp. 803-831, (2020); Baas J., Schotten M., Plume A., Cote G., Karimi R., Scopus as a curated, high-quality bibliometric data source for academic research in quantitative science studies, Quantitative Science Studies, 1, 1, pp. 377-386, (2020); Baber R., Baber P., Influence of social media marketing efforts, e-reputation and destination image on intention to visit among tourists: application of S-O-R model, Journal of Hospitality and Tourism Insights, 6, 5, pp. 2298-2316, (2023); Barnes S. J., Mattsson J., Sorensen F., Destination brand experience and visitor behavior: Testing a scale in the tourism context, Annals of Tourism Research, 48, pp. 121-139, (2014); Brida J. G., Pulina M., Riano E., Zapata-Aguirre S., Cruise visitors’ intention to return as land tourists and to recommend a visited destination, Anatolia, 23, 3, pp. 395-412, (2012); Burgos J. F. C., Padilla M., Nunez A., Varas-Diaz N., Matiz-Reyes A., An ethnographic study of “touristic escapism” and health vulnerability among Dominican male tourism workers, Global Public Health, 14, 11, pp. 1578-1588, (2019); Cetin G., Dincer F. I., Influence of customer experience on loyalty and word-of-mouth in hospitality operations, Anatolia, 25, 2, pp. 181-194, (2014); Chang K. C., Examining the Effect of Tour Guide Performance, Tourist Trust, Tourist Satisfaction, and Flow Experience on Tourists’ Shopping Behavior, Asia Pacific Journal of Tourism Research, 19, 2, pp. 219-247, (2014); Chen C.-F., Phou S., A closer look at destination: Image, personality, relationship and loyalty, Tourism Management, 36, pp. 269-278, (2013); Chen G., Xiao L., Selecting publication keywords for domain analysis in bibliometrics: A comparison of three methods, Journal of Informetrics, 10, 1, pp. 212-223, (2016); Chen N. C., Dwyer L., Firth T., Effect of dimensions of place attachment on residents’ word-of-mouth behavior, Tourism Geographies, 16, 5, pp. 826-843, (2014); Chew E. Y. T., Jahari S. A., Destination image as a mediator between perceived risks and revisit intention: A case of post-disaster Japan, Tourism Management, 40, pp. 382-393, (2014); Chiu W., Zeng S., Cheng P. S.-T., The influence of destination image and tourist satisfaction on tourist loyalty: a case study of Chinese tourists in Korea, International Journal of Culture, Tourism, and Hospitality Research, 10, 2, pp. 223-234, (2016); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Ek Styven M., Foster T., Who am I if you can’t see me? The “self” of young travellers as driver of eWOM in social media, Journal of Tourism Futures, 4, 1, pp. 80-92, (2018); Ellegaard O., Wallin J. A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, 3, pp. 1809-1831, (2015); Franco M. J. S., Tienda S. R., The role of user-generated content in tourism decision-making: an exemplary study of Andalusia, Spain, Management Decision, pp. 2014-2020, (2023); Galiano-Coronil A., Blanco-Moreno S., Tobar-Pesantez L. B., Gutierrez-Montoya G. A., Social media impact of tourism managers: a decision tree approach in happiness, social marketing and sustainability, Journal of Management Development, 42, 6, pp. 436-457, (2023); Gasparyan A. Y., Ayvazyan L., Kitas G. D., Multidisciplinary bibliographic databases, Journal of Korean Medical Science, 28, 9, pp. 1270-1275, (2013); Gavurova B., Skare M., Belas J., Rigelsky M., Ivankova V., The relationship between destination image and destination safety during technological and social changes COVID-19 pandemic, Technological Forecasting and Social Change, 191, (2023); Gavurova B., Skare M., Belas J., Rigelsky M., Ivankova V., The relationship between destination image and destination safety during technological and social changes COVID-19 pandemic, Technological Forecasting and Social Change, 191, (2023); Guo X., Urban tourism destination image: a bibliometric visualization review, Kybernetes, (2023); Huang G. I., Marion K., IpKin Anthony W., Rob L., Tourism destination research from 2000 to 2020: A systematic narrative review in conjunction with bibliographic mapping analysis, Tourism Management, 95, (2023); Jebbouri A., Zhang H., Imran Z., Iqbal J., Bouchiba N., Impact of Destination Image Formation on Tourist Trust: Mediating Role of Tourist Satisfaction, Frontiers in Psychology, 13, (2022); Jeong Y., Kim S., A study of event quality, destination image, perceived value, tourist satisfaction, and destination loyalty among sport tourists, Asia Pacific Journal of Marketing and Logistics, 32, 4, pp. 940-960, (2020); Jonas A. G., Radder L., van Eyk M., The influence of cognitive dimensions on memorable experiences within a marine tourism context, South African Journal of Economic and Management Sciences, 23, 1, pp. 1-14, (2020); Kanwel S., Lingqiang Z., Asif M., Hwang J., Hussain A., Jameel A., The Influence of Destination Image on Tourist Loyalty and Intention to Visit: Testing a Multiple Mediation Approach, Sustainability, 11, 22, (2019); Kim M. J., Lee C.-K., Petrick J. F., Kim Y. S., The influence of perceived risk and intervention on international tourists’ behavior during the Hong Kong protest: Application of an extended model of goal-directed behavior, Journal of Hospitality and Tourism Management, 45, pp. 622-632, (2020); Kullada P., Michelle Kurniadjie C. R., Examining the Influence of Digital Information Quality on Tourists’ Experience, Journal of Quality Assurance in Hospitality and Tourism, 22, 2, pp. 191-217, (2021); Lim W. M., Sahoo S., Agrawal A., Vijayvargy L., Fear of missing out and revenge travelling: the role of contextual trust, experiential risk, and cognitive image of destination, Journal of Travel and Tourism Marketing, 40, 7, pp. 583-601, (2023); Linnenluecke M. K., Marrone M., Singh A. K., Conducting systematic literature reviews and bibliometric analyses, Australian Journal of Management, 45, 2, pp. 175-194, (2019); Liu J., Wang C., Fang S., Zhang T., Scale development for tourist trust toward a tourism destination, Tourism Management Perspectives, 31, pp. 383-397, (2019); Luong T.-B., Celebrity involvement, film destination image, place attachment, behavioral intention: the moderating role of e-word of mouth utilitarian function, Asia Pacific Journal of Tourism Research, 28, 9, pp. 949-964, (2023); Ma J., Li F. S., How does self-construal shape tourists’ image perceptions of paradox destinations? The mediating roles of cognitive flexibility and destination involvement, Tourism Management, 95, (2023); Millan F. B., Almeida M., Escat-cortes M., Yi L., Sentiment analysis to measure quality and build sustainability in tourism destinations, Sustainability (Switzerland), 13, 11, (2021); Mogollon J. M. H., Alves H., Campon-Cerro A. M., Di-Clemente E., Integrating transactional and relationship marketing: a new approach to understanding destination loyalty, International Review on Public and Nonprofit Marketing, 18, 1, pp. 3-26, (2021); Mohammed Abubakar A., Does eWOM influence destination trust and travel intention: A medical tourism perspective, Economic Research-Ekonomska Istrazivanja, 29, 1, pp. 598-611, (2016); Navarro N., Community Perceptions of Tourism Impacts on Coastal Protected Areas, Journal of Marine Science and Engineering, 7, 8, (2019); Omo-Obas P., Anning-Dorson T., Cognitive-affective-motivation factors influencing international visitors’ destination satisfaction and loyalty, Journal of Hospitality and Tourism Insights, 6, 5, pp. 2222-2240, (2023); Oppermann M., Chon K. S., Time-series analysis of German outbound travel patterns, Journal of Vacation Marketing, 2, 1, pp. 39-52, (1995); Poon W. C., Koay K. Y., Hong Kong protests and tourism: Modelling tourist trust on revisit intention, Journal of Vacation Marketing, 27, 2, pp. 217-234, (2021); Prunonosa J. T., Batlle A. A., De Esteban Curiel J., Diez-Martin F., The intellectual structure of destination image research in tourism (2001–2023): Background, pre-pandemic overview, shifts during COVID-19 and implications for the future, Journal of Vacation Marketing, 30, 1, pp. 143-165, (2023); Rejeb A., Rejeb K., Treiblmaier H., Mapping Metaverse Research: Identifying Future Research Areas Based on Bibliometric and Topic Modeling Techniques, Information, 14, 7, (2023); Shim C., Park Y.-N., Lee C.-K., Sik Kim Y., Michael Hall C., Exploring protest tourism motivations: The case of Hong Kong, Tourist Studies, 22, 3, pp. 243-261, (2022); Sultan M. T., Sharmin F., Badulescu A., Gavrilut D., Xue K., Social media-based content towards image formation: A new approach to the selection of sustainable destinations, Sustainability (Switzerland), 13, 8, (2021); Tang L. R., Jang S. S., Information value and destination image: Investigating the moderating role of processing fluency, Journal of Hospitality Marketing and Management, 23, 7, pp. 790-814, (2014); Tasci A. D. A., Uslu A., Stylidis D., Woosnam K. M., Place-Oriented or People-Oriented Concepts for Destination Loyalty: Destination Image and Place Attachment versus Perceived Distances and Emotional Solidarity, Journal of Travel Research, 61, 2, pp. 430-453, (2022); Tham A., Croy G., Mair J., Social Media in Destination Choice: Distinctive Electronic Word-of-Mouth Dimensions, Journal of Travel and Tourism Marketing, 30, 1–2, pp. 144-155, (2013); Vidic G., WHICH TYPES OF DESTINATION IMAGE CONTENT ON SOCIAL MEDIA STIMULATES CONSUMER ENGAGEMENT? A QUASI-EXPERIMENTAL ANALYSIS, Acta Turistica, 34, 2, pp. 131-171, (2022); Wang Z., Udomwong P., Fu J., Onpium P., Destination image: A review from 2012 to 2023, Cogent Social Sciences, 9, 1, (2023); Yang Y., Liu X., Li J., How Customer Experience Affects the Customer-Based Brand Equity for Tourism Destinations, Journal of Travel and Tourism Marketing, 32, June, pp. S97-S113, (2015); Yu C., Hwang Y. S., Do the social responsibility efforts of the destination affect the loyalty of tourists?, Sustainability (Switzerland), 11, 7, (2019); Zhou B., Xiong Q., Li P., Liu S., Wang L.-E., Ryan C., Celebrity and film tourist loyalty: Destination image and place attachment as mediators, Journal of Hospitality and Tourism Management, 54, pp. 32-41, (2023); Zupic I., Cater T., Bibliometric Methods in Management and Organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","Suparman; Business Administration, Department of Social and Political Science, Universitas Padjadjaran, Bandung, Indonesia; email: suparman19001@mail.unpad.ac.id","","Success Culture Press","","","","","","24092665","","","","English","J. Logist. Inform. Serv. Sci.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-105001618011" -"Sujono R.I.; Rosari R.; Santoso C.B.; Susamto A.A.","Sujono, Rusny Istiqomah (59369534800); Rosari, Reni (58244378500); Santoso, Claudius Budi (59396871400); Susamto, Akhmad Akbar (57195902678)","59369534800; 58244378500; 59396871400; 57195902678","Bibliometric analysis of organizational learning in philanthropic organizations","2025","Learning Organization","","","","","","","0","10.1108/TLO-01-2024-0006","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85217862309&doi=10.1108%2fTLO-01-2024-0006&partnerID=40&md5=654ab46763c4e694d16e5fd280299a75","Doctoral Program in Islamic Economy and Halal Industry, Graduate School, Universitas Gadjah Mada, Yogyakarta, Indonesia and Department of Islamic Economics, Faculty of Economics and Business, Universitas Alma Ata, Yogyakarta, Indonesia; Doctoral Program in Islamic Economy and Halal Industry, Graduate School, Universitas Gadjah Mada, Yogyakarta, Indonesia; Department of Management, Faculty of Economics and Business, Universitas Gadjah Mada, Yogyakarta, Indonesia; Department of Economics, Faculty of Economics and Business, Universitas Gadjah Mada, Yogyakarta, Indonesia","Sujono R.I., Doctoral Program in Islamic Economy and Halal Industry, Graduate School, Universitas Gadjah Mada, Yogyakarta, Indonesia and Department of Islamic Economics, Faculty of Economics and Business, Universitas Alma Ata, Yogyakarta, Indonesia; Rosari R., Doctoral Program in Islamic Economy and Halal Industry, Graduate School, Universitas Gadjah Mada, Yogyakarta, Indonesia, Department of Management, Faculty of Economics and Business, Universitas Gadjah Mada, Yogyakarta, Indonesia; Santoso C.B., Doctoral Program in Islamic Economy and Halal Industry, Graduate School, Universitas Gadjah Mada, Yogyakarta, Indonesia, Department of Management, Faculty of Economics and Business, Universitas Gadjah Mada, Yogyakarta, Indonesia; Susamto A.A., Doctoral Program in Islamic Economy and Halal Industry, Graduate School, Universitas Gadjah Mada, Yogyakarta, Indonesia, Department of Economics, Faculty of Economics and Business, Universitas Gadjah Mada, Yogyakarta, Indonesia","Purpose: This study aims to examine publishing patterns regarding the incorporation of organizational learning in philanthropic organizations. Design/methodology/approach: This study conducts a quantitative bibliometric analysis using Scopus database data from 1997 to 2024. The search terms “organizational learning” combined with “philanthropy,” “non-profit,” “nonprofit,” “charity,” “humanitarian” or “endowment” yielded 162 articles. The data were processed in RStudio using the Bibliometrix R package, specifically the Biblioshiny component. Findings: The results of the bibliometric analysis indicate a significant increase in research interest in the theme of organizational learning within philanthropic organizations from 1997 to 2024. This analysis also elucidates the relationships among the most prolific authors based on the country of their affiliated universities, the collaborations that have taken place, the most cited documents, keywords and the scientific knowledge used. Research limitations/implications: A comprehensive literature review will be valuable for future researchers aiming to build a robust conceptual framework. This study’s science mapping is limited to the Scopus database and languages. Originality/value: To the best of the authors’ knowledge, this study is the first to describe research patterns focusing on organizational learning in philanthropic organizations. © 2025, Emerald Publishing Limited.","Bibliometrics; Organizational learning; Philanthropy","","","","","","","","Alnamrouti A., Rjoub H., Ozgit H., Do strategic human resources and artificial intelligence help to make organisations more sustainable? Evidence from non-governmental organisations, Sustainability (Switzerland), 14, 12, (2022); Andjelkovic O., Boolaky M., Organizational learning: A case study of an international non-profit organization, International Journal of Business Administration, 6, 2, pp. 124-137, (2015); Argote L., Miron-Spektor E., Organizational learning: From experience to knowledge, Organization Science, 22, 5, pp. 1123-1137, (2011); Argyris C., On organizational learning, (1999); Argyris C., Schon D.A., Organizational learning: A theory of action perspective, Reis, 77-78, pp. 345-348, (1978); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Brix J., Exploring knowledge creation processes as a source of organizational learning: A longitudinal case study of a public innovation project, Scandinavian Journal of Management, 33, 2, pp. 113-127, (2017); Callias K.M., Grady H., Grosheva K., Philanthropy’s contributions to the sustainable development goals in emerging countries lessons learnt and experiences from the SDG philanthropy platform, European Research Network on Philanthropy, 8, July, pp. 1-22, (2017); 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Susilowati T., Nuswantoro M.A., Susiatin E., Evi E., Effect of training & development, organizational learning on employee competence, EduLine: Journal of Education and Learning Innovation, 2, 2, pp. 182-192, (2022); Thompson B.S., Payments for ecosystem services and corporate social responsibility: Perspectives on sustainable production, stakeholder relations, and philanthropy in Thailand, Business Strategy and the Environment, 28, 4, pp. 497-511, (2019); Tran R., Shah S., Designing for learning: One foundation’s efforts to institutionalize organizational learning, Foundation Review, 5, 3, pp. 28-34, (2013); Visser M., Organizational learning capability and battlefield performance: The British army in world war II, International Journal of Organizational Analysis, 24, 4, pp. 573-590, (2016); Williams A., Blasberg L.A., SDG platforms as strategic innovation through partnerships, Journal of Business Ethics, 180, 4, pp. 1041-1057, (2022); Wirtz B.W., Balzer I., Schmitt D., Mobile government: Research development and research perspectives, International Journal of Public Administration, 46, 4, pp. 269-290, (2023); Yadav M., Banerji P., A bibliometric analysis of digital financial literacy, American Journal of Business, 38, 3, pp. 91-111, (2023); Yang D., Babiak K., A study on corporate foundation and philanthropy: Does governance matter for organizational performance?, Nonprofit Management and Leadership, 34, 1, pp. 59-80, (2023); Yang J.T., The impact of knowledge sharing on organizational learning and effectiveness, Journal of Knowledge Management, 11, 2, pp. 83-90, (2007); Fighting for Victory on The Learning Battlefield, Development and Learning in Organizations: An International Journal, 31, 4, pp. 24-26, (2017); Carman J.G., Evaluation in an era of accountability: Unexpected Opportunities - A reply to Jill Chouinard, American Journal of Evaluation, 34, 2, pp. 261-265, (2013); Kaplan R.S., Strategic performance measurement and management in nonprofit organizations, Nonprofit Management and Leadership, 11, 3, pp. 353-370, (2001); Moynihan D.P., Goal-based learning and the future of performance management, Public Administration Review, 65, 2, pp. 203-216, (2005); Perkins D.D., Dess K.D., Cooper D.G., Jones D.L., Armsread T., Speer P.W., Community organizational learning: Case studies illustrating a three-dimensional model of levels and orders of change, Journal of Community Psychology, 35, 3, pp. 303-328, (2007)","R.I. Sujono; Doctoral Program in Islamic Economy and Halal Industry, Graduate School, Universitas Gadjah Mada, Yogyakarta, Indonesia and Department of Islamic Economics, Faculty of Economics and Business, Universitas Alma Ata, Yogyakarta, Indonesia; email: rusny.istiqomah.s@mail.ugm.ac.id","","Emerald Publishing","","","","","","09696474","","","","English","Learn. Organ.","Review","Article in press","","Scopus","2-s2.0-85217862309" -"Brabete V.; Sichigea M.; Cîrciumaru D.; Goagără D.","Brabete, Valeriu (36674485000); Sichigea, Mirela (57204365877); Cîrciumaru, Daniel (55014332200); Goagără, Daniel (35302395300)","36674485000; 57204365877; 55014332200; 35302395300","Bibliometric Mapping of the Relationships Between Accounting, Professional Accountants, and Sustainability Issues","2024","Sustainability (Switzerland)","16","21","9508","","","","0","10.3390/su16219508","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85208612079&doi=10.3390%2fsu16219508&partnerID=40&md5=0567448c7d0bd46ae29de5a988d1291d","Department of Economics, Accounting and International Affairs, Faculty of Economics and Business Administration, University of Craiova, Craiova, 200585, Romania; Department Finance, Banking and Economic Analysis, Faculty of Economics and Business Administration, University of Craiova, Craiova, 200585, Romania","Brabete V., Department of Economics, Accounting and International Affairs, Faculty of Economics and Business Administration, University of Craiova, Craiova, 200585, Romania; Sichigea M., Department Finance, Banking and Economic Analysis, Faculty of Economics and Business Administration, University of Craiova, Craiova, 200585, Romania; Cîrciumaru D., Department Finance, Banking and Economic Analysis, Faculty of Economics and Business Administration, University of Craiova, Craiova, 200585, Romania; Goagără D., Department of Economics, Accounting and International Affairs, Faculty of Economics and Business Administration, University of Craiova, Craiova, 200585, Romania","The accounting profession plays a crucial role in serving public interest by establishing the foundation for sustainable development and taking on social responsibility. The growing focus on sustainability practices of companies and stakeholders has also had a significant impact on the role of accounting and professional accountants. This has led to increased expectations for greater involvement in integrating sustainability into corporate decision making at every level. We used a bibliometric analysis of academic literature as a research method to identify the relationships between accounting, professional accountants, and sustainability issues (APASI). Bibliometrix R-package and VOSviewer were used to achieve the proposed objectives. This study analyzes the performance of the scientific literature, establishes the conceptual, intellectual, and social structure of research, and identifies new research directions. A period of 37 years (1987–2024) is taken into consideration, with 2556 documents and 859 sources extracted from the Web of Science database analyzed. We offer, in an original manner, descriptive statistics and relevant landmarks of the sources, authors, publications, organizations, and countries that have contributed significantly to the development of research in this field. Interested researchers have the opportunity to identify scholars for potential collaborations and valuable study resources. © 2024 by the authors.","accounting; bibliometric mapping; performance analysis; professionals accountants; science mapping; sustainability","database; decision making; research method; social structure; sustainability; sustainable development","","","","","","","Gulluscio C., Puntillo P., Luciani V., Huisingh D., Climate Change Accounting and Reporting: A Systematic Literature Review, Sustainability, 12, (2020); Cairns R.D., On accounting for sustainable development and accounting for the environment, Resour. Policy, 31, pp. 211-216, (2006); Gray R., Is accounting for sustainability actually accounting for sustainability…and how would we know? An exploration of narratives of organisations and the planet, Account. Org. Soc, 35, pp. 47-62, (2010); Wenzig J., Nuzum A.K., Schaltegger S., Path dependence of accountants: Why are they not involved in corporate sustainability?, Bus. Strateg. Environ, 32, pp. 2662-2683, (2023); Caliskan O.A., How accounting and accountants may contribute in sustainability?, Soc. Responsib. J, 10, pp. 246-267, (2014); Ballou B., Casey R.J., Grenier J.H., Heitger D.L., Exploring the Strategic Integration of Sustainability Initiatives: Opportunities for Accounting Research, Account. 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Res, 25, pp. 461-480, (2017); de Villiers C., Venter E.R., Hsiao P.-C.K., Integrated reporting: Background, measurement issues, approaches and an agenda for future research, Account. Financ, 57, pp. 937-959, (2017); De Stefano D., Giordano G., Vitale M.P., Issues in the analysis of co-authorship networks, Qual. Quant, 45, pp. 1091-1107, (2011); Kumar S., Co-authorship networks: A review of the literature, Aslib J. Inf. Manag, 67, pp. 55-73, (2015); Uddin S., Hossain L., Abbasi A., Rasmussen K., Trend and efficiency analysis of co-authorship network, Scientometrics, 90, pp. 687-699, (2012)","V. Brabete; Department of Economics, Accounting and International Affairs, Faculty of Economics and Business Administration, University of Craiova, Craiova, 200585, Romania; email: valeriu-daniel.brabete@edu.ucv.ro","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20711050","","","","English","Sustainability","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85208612079" -"San-Juan-Heras R.; Gabriel J.L.; Delgado M.M.; Alvarez S.; Martinez S.","San-Juan-Heras, Raúl (57733126100); Gabriel, José L. (37037213700); Delgado, María M. (36951071200); Alvarez, Sergio (57192575015); Martinez, Sara (57196217869)","57733126100; 37037213700; 36951071200; 57192575015; 57196217869","Scientometric analysis of cover crop management: Trends, networks, and future directions","2024","European Journal of Agronomy","161","","127355","","","","4","10.1016/j.eja.2024.127355","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85204377464&doi=10.1016%2fj.eja.2024.127355&partnerID=40&md5=e2b0af105342f8bb0a1231d3330582f3","Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), CSIC, Environment and Agronomy Department, Ctra de la Coruña km. 7,5, Madrid, 28040, Spain; Escuela Técnica Suerior de Ingeniería Agronómica, Alimentaria y de Biosistemas, Universidad Politécnica de Madrid, Av. Puerta de Hierro 2, Madrid, 28040, Spain; Centro de Estudios e Investigación para la Gestión de Riesgos Agrarios y Medioambientales (CEIGRAM-UPM), Madrid, 28040, Spain; Departamento de Ingeniería y Morfología del Terreno, Escuela Técnica Superior de Ingenieros de Caminos Canales y Puertos, Universidad Politécnica de Madrid, Calle del Profesor Aranguren 3, Madrid, 28040, Spain","San-Juan-Heras R., Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), CSIC, Environment and Agronomy Department, Ctra de la Coruña km. 7,5, Madrid, 28040, Spain, Escuela Técnica Suerior de Ingeniería Agronómica, Alimentaria y de Biosistemas, Universidad Politécnica de Madrid, Av. Puerta de Hierro 2, Madrid, 28040, Spain; Gabriel J.L., Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), CSIC, Environment and Agronomy Department, Ctra de la Coruña km. 7,5, Madrid, 28040, Spain, Centro de Estudios e Investigación para la Gestión de Riesgos Agrarios y Medioambientales (CEIGRAM-UPM), Madrid, 28040, Spain; Delgado M.M., Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), CSIC, Environment and Agronomy Department, Ctra de la Coruña km. 7,5, Madrid, 28040, Spain; Alvarez S., Departamento de Ingeniería y Morfología del Terreno, Escuela Técnica Superior de Ingenieros de Caminos Canales y Puertos, Universidad Politécnica de Madrid, Calle del Profesor Aranguren 3, Madrid, 28040, Spain; Martinez S., Departamento de Ingeniería y Morfología del Terreno, Escuela Técnica Superior de Ingenieros de Caminos Canales y Puertos, Universidad Politécnica de Madrid, Calle del Profesor Aranguren 3, Madrid, 28040, Spain","This research paper presents a comprehensive scientometric analysis of English articles from the Scopus database regarding the topic of cover crop management from 1956 to March 2024. Through the analysis of the annual production trend, total production, a co-occurrence network of keywords, co-authorship networks, and co-citation networks, the data was mapped and visualized using VOSviewer and Bibliometrix software. There was an exponential increase in publications from 1991 onwards. The predominant subject was Agricultural and Biological Sciences and the most relevant journals, authors, and documents were related to this topic. Additionally, the most productive country was the United States, but in terms of article production per surface area, other countries, such as Switzerland and The Netherlands, evidence the great weight of cover crop management in these countries. The identified research topics were related to the application of different crops as cover crops and the effects on different cultivars, also soil quality improvement, and fertilization and nutrient efficiency. An emerging research topic was found to be the usefulness of cover crops as effective tools for climate change adaptation and mitigation strategies in agriculture. Future research in the field of cover crop management could be directed towards climate-adaptive cover crop species and varieties, the use of technological innovations for cover crop monitoring, and management and analysis of the economic and social impacts of cover crop adoption. © 2024 The Authors","Agriculture; Bibliometric analysis; Crops; Science mapping; VOSviewer","Netherlands; Switzerland; United States; alternative agriculture; climate change; cover crop; crop plant; cultivation; economic impact; soil quality; surface area","","","","","PTI","This study was supported by the project PID2021-124041OB-C21.RESUENA-Legumes, funded by MCIN/AEI/10.13039/501100011033/, and by PTI AGRIAMBIO (MAPA-CSIC agreement). The authors would like to thank Adri\u00E1n Garc\u00EDa. 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J., 107, 6, (2015); Nordblom T., Gurusinghe S., Erbacher A., Weston L.A., Opportunities and Challenges for Cover Cropping in Sustainable Agriculture Systems in Southern Australia, Agriculture, 13, 3, (2023); Peterson C.A., Bell L.W., Carvalho P.C.D.F., Gaudin A.C.M., Resilience of an integrated crop–livestock system to climate change: a simulation analysis of cover crop grazing in Southern Brazil, Front. Sustain. Food Syst., 4, (2020); Plaza-Bonilla D., Nolot J.M., Raffaillac D., Justes E., Innovative cropping systems to reduce N inputs and maintain wheat yields by inserting grain legumes and cover crops in southwestern France, Eur. J. Agron., 82, (2017); Quintarelli V., Radicetti E., Allevato E., Stazi S.R., Haider G., Abideen Z., Bibi S., Jamal A., Mancinelli R., Cover crops for sustainable cropping systems: a review, Agriculture, 12, 12, (2022); Salinas-Rios K., Garcia Lopez A.J., Bibliometrics, a useful tool within the field of research, J. Basic Appl. Psychol. Res., 3, 6, (2022); Teasdale J.R., Mohler C.L., The quantitative relationship between weed emergence and the physical properties of mulches, Weed Sci., 48, 3, (2000); Thorup-Kristensen K., Magid J., Jensen L.S., Catch crops and green manures as biological tools in nitrogen management in temperate zones, Adv. Agron., 79, (2003); van Eck N.J., Waltman L., Visualizing Bibliometric Networks, Meas. Sch. Impact, (2014); Vann R.A., Reberg-Horton S.C., Castillo M.S., McGee R.J., Mirsky S.B., Winter pea, crimson clover, and hairy vetch planted in mixture with small grains in the southeast United States, Agron. J., 111, 2, (2019); Wallace J.M., Williams A., Liebert J.A., Ackroyd V.J., Vann R.A., Curran W.S., Keene C.L., Vangessel M.J., Ryan M.R., Mirsky S.B., Cover crop-based, organic rotational no-till corn and soybean production systems in the mid-atlantic United States, Agric. (Switz.), 7, 4, (2017); Zhang H., Ghahramani A., Ali, Erbacher, Cover cropping impacts on soil water and carbon in dryland cropping system, PLoS ONE, 18, 6 June, (2023); Zhou Q., Guan K., Wang S., Jiang C., Huang Y., Peng B., Chen Z., Wang S., Hipple J., Schaefer D., Qin Z., Stroebel S., Coppess J., Khanna M., Cai Y., Recent rapid increase of cover crop adoption across the U.S. midwest detected by fusing multi-source satellite data, Geophys. Res. Lett., 49, 22, (2022)","J.L. Gabriel; INIA-CSIC, Departamento de Medio Ambiente y Agronomía, Madrid, Ctra de la Coruña, km 7.5, 28040, Spain; email: gabriel.jose@inia.csic.es","","Elsevier B.V.","","","","","","11610301","","EJAGE","","English","Eur. J. Agron.","Article","Final","All Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-85204377464" -"Huang S.S.","Huang, Songshan (Sam) (35214708800)","35214708800","A comprehensive science mapping of tourism and hospitality research: Tribes, territories and networks","2025","Journal of Hospitality, Leisure, Sport and Tourism Education","36","","100523","","","","3","10.1016/j.jhlste.2024.100523","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85209679024&doi=10.1016%2fj.jhlste.2024.100523&partnerID=40&md5=e7dc98f03a5edd241a3fd7fa2f921670","School of Business and Law, Edith Cowan University, Australia","Huang S.S., School of Business and Law, Edith Cowan University, Australia","This study aims to provide a comprehensive bibliographic analysis of the field of tourism and hospitality research by mapping the contributions of researchers, research institutions and evolution of research topics and collaboration networks. Metadata from 27 SSCI and 30 ESCI tourism and hospitality journals were collected from Web of Science. Data analysis was conducted utilizing R package of Bibliometrix and Biblioshiny, adhering to the guidelines of bibliometric analysis. The study identified topics of sustainability and IT technology applications in tourism and hospitality as the recent research fronts. An increasing number of Chinese origin researchers emerged in the author collaboration network, followed by Korean origin researchers. Authors and universities in China started to form distinctive clusters in the author and institutional collaboration networks. The results offer a holistic understanding of the field of tourism and hospitality research, and can help researchers develop personal strategies in research career planning and development. © 2024 The Author","Bibliometric analysis; Bibliometrix; Biblioshiny; Hospitality; Science mapping; Tourism","","","","","","","","Adams J., Fry R., Pendlebury D., Potter R., Rogers G., Global research report: China's research landscape, (2023); Airey D., Fifty years of tourism education in annals, Annals of Tourism Research, 104, (2024); Ajzen I., The theory of planned behavior, Organizational Behavior and Human Decisioni Processes, 50, pp. 179-211, (1991); Anderson J.C., Gerbing D.W., Structural equation modeling in practice: A review and recommended two-step approach, Psychological Bulletin, 103, 3, pp. 411-423, (1988); Ap J., Residents' perceptions on tourism impacts, Annals of Tourism Research, 19, pp. 665-690, (1992); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); 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Hosp. Leis. Sports Tour. Educ.","Article","Final","All Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-85209679024" -"Moroz D.","Moroz, David (57210255399)","57210255399","On What Topics Does the Scientific Community Cooperate in Defense Economics? A Science Mapping of the First 30 Years of the Journal Defence and Peace Economics","2025","Defence and Peace Economics","36","4","","555","576","21","0","10.1080/10242694.2024.2377964","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198394133&doi=10.1080%2f10242694.2024.2377964&partnerID=40&md5=056a41d6d63725205c01fcccd6f2ee91","Metis Lab, EM Normandie Business School, Métis Lab, Paris, Clichy, France","Moroz D., Metis Lab, EM Normandie Business School, Métis Lab, Paris, Clichy, France","The academic journal Defence and Peace Economics, which celebrated its pearl jubilee in 2024, is acknowledged as the leading journal in defense economics, bringing together a scientific community of authors from a diverse array of countries. We conduct a bibliometric study using science mapping to analyze the evolution of author networks and research themes within the journal from 1994 to 2023. Analyzing 1069 articles, our findings reveal a growing internationalization of the journal, alongside an increasing diversification of topics. However, we observe a decrease in the rate of international co-authorship during the most recent period of our analysis, i.e. 2019-2023. The core of the publications remains focused on military spending and its interconnection with economic growth. Moreover, our analysis points to themes related to technology, innovation, and R&D in the defense industry as research opportunities. © 2024 Informa UK Limited, trading as Taylor & Francis Group.","bibliometrix; defence and peace economics; Science mapping; Scopus; SPAR-4-SLR","","","","","","","","Arce D., Cybersecurity for Defense Economists, Defence and Peace Economics, 34, 6, pp. 705-725, (2023); Arce D., Kollias C., Defence and Peace Economics: The Second Decade in Retrospect, Defence and Peace Economics, 21, 5-6, pp. 395-407, (2010); Aria M., Cuccurullo C., Bibliometrix: Comprehensive Science Mapping Analysis; Aria M., Cuccurullo C., CouplingMap: Coupling Analysis, Bibliometrix: Comprehensive Science Mapping Analysis; Aria M., Cuccurullo C., NormalizeCitationscore: Calculate the Normalized Citation Score Metric, Bibliometrix: Comprehensive Science Mapping Analysis; Aria M., Cuccurullo C., Bibliometrix: An R-Tool for Comprehensive Science Mapping Analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aziz N., Khalid U., Armed Conflict, Military Expenses and FDI Inflow to Developing Countries, Defence and Peace Economics, 30, 2, pp. 238-251, (2019); Baas J., Schotten M., Plume A., Cote G., Karimi R., Scopus As a Curated, High-Quality Bibliometric Data Source for Academic Research in Quantitative Science Studies, Quantitative Science Studies, 1, 1, pp. 377-386, (2020); Balcaen P., Du Bois C., Buts C., A Game-Theoretic Analysis of Hybrid Threats, Defence and Peace Economics, 33, 1, pp. 26-41, (2022); Balcaen P., Du Bois C., Buts C., Sharing the Burden of Hybrid Threats: Lessons from the Economics of Alliances, Defence and Peace Economics, 34, 2, pp. 142-159, (2023); Blum J., Potrafke N., Does a Change of Government Influence Compliance with International Agreements? Empirical Evidence for the NATO Two Percent Target, Defence and Peace Economics, 31, 7, pp. 743-761, (2020); Bouri E., Demirer R., Gupta R., Marfatia H.A., Geopolitical Risks and Movements in Islamic Bond and Equity Markets: A Note, Defence and Peace Economics, 30, 3, pp. 367-379, (2019); Bouri E., Gupta R., Vinh Vo X., Jumps in Geopolitical Risk and the Cryptocurrency Market: The Singularity of Bitcoin, Defence and Peace Economics, 33, 2, pp. 150-161, (2022); Callado-Munoz F.J., Fernandez-Olmos M., Marisa R.-A., Natalia U.-G., Characterisation of Technological Collaborations and Evolution in the Spanish Defence Industry, Defence and Peace Economics, 33, 2, pp. 219-238, (2022); Callado-Munoz F.J., Fernandez-Olmos M., Ramirez-Aleson M., Maria Utrero-Gonzalez N., Assessing the Impact of Military and Civilian R&D on Performance, Defence and Peace Economics, pp. 1-17, (2023); Callado-Munoz F.J., Hromcova J., Laborda Herrero R., Utrero Gonzalez N., An Empirical Analysis of Arms Exports and Economic Growth Spillovers: The Case of the United States, Defence and Peace Economics, 34, 7, pp. 893-913, (2023); Callado-Munoz F.J., Hromcova J., Sanso-Navarro M., Utrero-Gonzalez N., Vera-Cabello M., Firm Performance in Regulated Markets: The Case of Spanish Defence Industry, Defence and Peace Economics, 33, 2, pp. 201-218, (2022); Callon M., Courtial J.P., Laville F., Co-Word Analysis As a Tool for Describing the Network of Interactions Between Basic and Technological Research: The Case of Polymer Chemsitry, Scientometrics, 22, 1, pp. 155-205, (1991); Callon M., Courtial J.-P., Turner W.A., Bauin S., From Translations to Problematic Networks: An Introduction to Co-Word Analysis, Social Science Information, 22, 2, pp. 191-235, (1983); Chang Y.-W., Huang M.-H., Lin C.-W., Evolution of Research Subjects in Library and Information Science Based on Keyword, Bibliographical Coupling, and Co-Citation Analyses, Scientometrics, 105, 3, pp. 2071-2087, (2015); Christie E.H., The Demand for Military Expenditure in Europe: The Role of Fiscal Space in the Context of a Resurgent Russia, Defence and Peace Economics, 30, 1, pp. 72-84, (2019); 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Khalid U., Habimana O., Military Spending and Economic Growth in Turkey: A Wavelet Approach, Defence and Peace Economics, 32, 3, pp. 362-376, (2021); Khan K., Su C.-W., Kumail Abbas Rizvi S., Guns and Blood: A Review of Geopolitical Risk and Defence Expenditures, Defence and Peace Economics, 33, 1, pp. 42-58, (2022); Khan K., Su C.-W., Tao R., Does Oil Prices Cause Financial Liquidity Crunch? Perspective from Geopolitical Risk, Defence and Peace Economics, 32, 3, pp. 312-324, (2021); Kim W., Sandler T., NATO at 70: Pledges, Free Riding, and Benefit-Burden Concordance, Defence and Peace Economics, 31, 4, pp. 400-413, (2020); Kim W., Sandler T., NATO Security Burden Sharing, 1991–2020, Defence and Peace Economics, 35, 3, pp. 265-280, (2023); Kraus S., Breier M., Marc Lim W., Dabic M., Kumar S., Kanbach D., Mukherjee D., Et al., Literature Reviews As Independent Studies: Guidelines for Academic Practice, Review of Managerial Science, 16, 8, pp. 2577-2595, (2022); Lim W.M., Kumar S., Ali F., Advancing Knowledge Through Literature Reviews: ‘What’, ‘Why’, and ‘How to Contribute’, The Service Industries Journal, 42, 7-8, pp. 481-513, (2022); Moher D., Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement, Annals of Internal Medicine, 151, 4, (2009); Moher D., Shamseer L., Clarke M., Ghersi D., Liberati A., Petticrew M., Shekelle P., Stewart L.A., Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) 2015 Statement, Systematic Reviews, 4, 1, (2015); Mukherjee D., Kumar S., Donthu N., Pandey N., Research Published in Management International Review from 2006 to 2020: A Bibliometric Analysis and Future Directions, Management International Review, 61, 5, pp. 599-642, (2021); Mukherjee D., Marc Lim W., Kumar S., Donthu N., Guidelines for Advancing Theory and Practice Through Bibliometric Research, Journal of Business Research, 148, September, pp. 101-115, (2022); Ozturk O., Kocaman R., Kanbach D.K., How to Design Bibliometric Research: An Overview and a Framework Proposal, Review of Managerial Science, (2024); Paul J., Marc Lim W., O'Cass A., Wei Hao A., Bresciani S., Scientific Procedures and Rationales for Systematic Literature Reviews (SPAR‐4‐SLR), International Journal of Consumer Studies, 45, 4, (2021); Paul J., Rialp Criado A., The Art of Writing Literature Review: What Do We Know and What Do We Need to Know?, International Business Review, 29, 4, (2020); Peksen D., Autocracies and Economic Sanctions: The Divergent Impact of Authoritarian Regime Type on Sanctions Success, Defence and Peace Economics, 30, 3, pp. 253-268, (2019); Peksen D., When Do Imposed Economic Sanctions Work? A Critical Review of the Sanctions Effectiveness Literature, Defence and Peace Economics, 30, 6, pp. 635-647, (2019); Peksen D., Mun Jeong J., Coercive Diplomacy and Economic Sanctions Reciprocity: Explaining Targets’ Counter-Sanctions, Defence and Peace Economics, 33, 8, pp. 895-911, (2022); Purnell P.J., The Prevalence and Impact of University Affiliation Discrepancies Between Four Bibliographic Databases—Scopus, Web of Science, Dimensions, and Microsoft Academic, Quantitative Science Studies, 3, 1, pp. 99-121, (2022); Rogers G., Szomszor M., Adams J., Sample Size in Bibliometric Analysis, Scientometrics, 125, 1, pp. 777-794, (2020); Sanso-Navarro M., Sanz Gracia F., Vera-Cabello M., Terrorism Determinants, Model Uncertainty and Space in Colombia, Defence and Peace Economics, 34, 1, pp. 92-111, (2023); Sanso-Navarro M., Vera-Cabello M., The Socioeconomic Determinants of Terrorism: A Bayesian Model Averaging Approach, Defence and Peace Economics, 31, 3, pp. 269-288, (2020); Snyder H., Literature Review As a Research Methodology: An Overview and Guidelines, Journal of Business Research, 104, November, pp. 333-339, (2019); Song Y., Lei L., Wu L., Chen S., Studying Domain Structure: A Comparative Analysis of Bibliographic Coupling Analysis and Co-Citation Analysis Considering All Authors, Online Information Review, 47, 1, pp. 123-137, (2023); Su C.-W., Meng Q., Ran T., Moldovan N.-C., Is Oil Political? From the Perspective of Geopolitical Risk, Defence and Peace Economics, 32, 4, pp. 451-467, (2021); Szomszor M., Adams J., Fry R., Gebert C., Pendlebury D.A., Potter R.W.K., Rogers G., Interpreting Bibliometric Data, (2021); Yan Y., Guan J., Social Capital, Exploitative and Exploratory Innovations: The Mediating Roles of Ego-Network Dynamics, Technological Forecasting & Social Change, 126, January, pp. 244-258, (2018); Zhao D., Strotmann A., Author Bibliographic Coupling: Another Approach to Citation-Based Author Knowledge Network Analysis, Proceedings of the ASIST Annual Meeting, 45, (2008); Zhao D., Strotmann A., Evolution of Research Activities and Intellectual Influences in Information Science 1996–2005: Introducing Author Bibliographic‐Coupling Analysis, Journal of the American Society for Information Science and Technology, 59, 13, pp. 2070-2086, (2008); Zupic I., Cater T., Bibliometric Methods in Management and Organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","D. Moroz; Métis Lab, EM Normandie Business School, Clichy, 30-32 rue Henri Barbusse, 92110, France; email: dmoroz@em-normandie.fr","","Routledge","","","","","","10242694","","","","English","Def. Peace Econ.","Article","Final","","Scopus","2-s2.0-85198394133" -"Agrawal D.","Agrawal, Devika (57225754747)","57225754747","Tech-Driven Progress: Leveraging Technology in Advancing Sustainable Development Goals in Emerging Economies","2025","Sustainable Development Goals Series","Part F441","","","75","89","14","0","10.1007/978-3-031-86500-8_6","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105006829181&doi=10.1007%2f978-3-031-86500-8_6&partnerID=40&md5=d3763a6561bd841d32d5b3a364275a55","Institute of Business Management, GLA University, Mathura, India","Agrawal D., Institute of Business Management, GLA University, Mathura, India","The role of technology is pivotal in attaining sustainable development goals (SDGs) across the globe, particularly in emerging countries where the impact of technology can be very transformational. This book chapter explores the multifaceted relationship between technological innovation and the attainment of SDGs. It also provides a comprehensive analysis of how technology plays a great role in facilitating sustainable development. We have undergone a thorough examination of multiple technologies from diverse emerging economies to exemplify the successful integration of technology in sustainable development, through a bibliometric analysis of 6689 documents extracted from the Scopus database, we have undertaken performance analysis and science mapping by using software like R-studio Package, bibliometrix, and VOSviewer. The findings revealed China and India are the leading countries in our domain of study, four major clusters have emerged from our bibliographic couplings, namely: (a) Circular economy and decision-making, (b) Supply chain management and sustainability, (c) Sustainable energy utilization and economic impact, (d) Sustainability innovation and environmental economics. Furthermore, this chapter provides how the strategic implementation of technology is crucial for accelerating SDG adoption in various emerging economies. Through collaborative initiatives, supportive and robust mechanisms and governance policies are created to harness technology’s full potential for the advancements of SDGs. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.","Artificial intelligence; Blockchain and IoT; Information and communication technologies; Renewable energy; Sustainable development; Sustainable development goals (SDGs); Technological innovation","","","","","","","","Agrawal M.D., Perception and attitude of taxpayers towards digitalisation of tax, Perception, 29, 5, pp. 7093-7102, (2020); Agrawal D., Kumar K., Rahman O., ESG Investment Strategy. in Reference Module in Social Sciences, (2024); Awan U., Shamim S., Khan Z., Zia N.U., Shariq S.M., Khan M.N., Big data analytics capability and decision-making: The role of data-driven insight on circular economy performance, Technological Forecasting and Social Change, 168, (2021); Chege S.M., Wang D., The influence of technology innovation on SME performance through environmental sustainability practices in Kenya, Technology in Society, 60, (2020); Daga S., Yadav K., Singh P., Yadav B., Navigating Towards a Greener Tomorrow: The Imperative of Sustainable Tourism in The Era of Global Climate Change. in The Need for Sustainable Tourism in an Era of Global Climate Change: Pathway to a Greener Future, pp. 1-12, (2024); de Guimaraes J.C.F., Severo E.A., Junior L.A.F., da Costa W.P.L.B., Salmoria F.T., Governance and quality of life in smart cities: Towards sustainable development goals, Journal of Cleaner Production, 253, (2020); de Sousa Jabbour A.B.L., Jabbour C.J.C., Foropon C., Godinho Filho M., When titans meet– Can industry 4.0 revolutionise the environmentally-sustainable manufacturing wave? The role of critical success factors, Technological Forecasting and Social Change, 132, pp. 18-25, (2018); Destek M.A., Sinha A., Renewable, nonrenewable energy consumption, economic growth, trade openness and ecological footprint: Evidence from organisation for economic co-operation and development countries, Journal of Cleaner Production, 242, (2020); Di Vaio A., Palladino R., Hassan R., Escobar O., Artificial intelligence and business models in the sustainable development goals perspective: A systematic literature review, Journal of Business Research, 121, pp. 283-314, (2020); Fatimah Y.A., Govindan K., Murniningsih R., Setiawan A., Industry 4.0 based sustainable circular economy approach for smart waste management system to achieve sustainable development goals: A case study of Indonesia, Journal of Cleaner Production, 269, (2020); Govindan K., Shaw M., Majumdar A., Social sustainability tensions in multi-tier supply chain: A systematic literature review towards conceptual framework development, Journal of Cleaner Production, 279, (2021); Javed A.R., Shahzad F., Ur Rehman S., Zikria Y.B., Razzak I., Jalil Z., Xu G., Future smart cities: Requirements, emerging technologies, applications, challenges, and future aspects, Cities, 129, (2022); Kandpal V., Reaching sustainable development goals: Bringing financial inclusion to reality in India, Journal of Public Affairs, (2020); Kapoor D., Jain A., Sustainable tourism and its future research directions: A bibliometric analysis of twenty-five years of research, Tourism Review, 79, 3, pp. 541-567, (2024); Kraus S., Rehman S.U., Garcia F.J.S., Corporate social responsibility and environmental performance: The mediating role of environmental strategy and green innovation, Technological Forecasting and Social Change, 160, (2020); Kumar K., Prakash A., Developing a framework for assessing sustainable banking performance of the Indian banking sector, Social Responsibility Journal, 15, 5, pp. 689-709, (2019); Kumar K., Prakash A., Khan W., Integrating the notion of sustainable development in banking: Analysing historical and conceptual framework, Indian Journal of Economics and Development, 16, 3, pp. 449-458, (2020); Kumar R., Kumar K., Singh R., Sa J.C., Carvalho S., Santos G., Modeling environmentally conscious purchase behavior: Examining the role of ethical obligation and green self-identity, Sustainability, 15, 8, (2023); Malav L.C., Yadav K.K., Gupta N., Kumar S., Sharma G.K., Krishnan S., Rezania S., Kamyab H., Pham Q.B., Yadav S., A review on municipal solid waste as a renewable source for waste-to-energy project in India: Current practices, challenges, and future opportunities, Journal of Cleaner Production, 277, (2020); Menani S., FDI and FII as drivers of growth for Indian economy: A Comparison, International Journal of Innovative Research and Development, 2, 13, pp. 209-216, (2013); Mihalic T., Metaversal sustainability: Conceptualisation within the sustainable tourism paradigm, Tourism Review, (2024); Orji I.J., Kusi-Sarpong S., Huang S., Vazquez-Brust D., Evaluating the factors that influence blockchain adoption in the freight logistics industry, Transportation Research Part E: Logistics and Transportation Review, 141, (2020); Pournader M., Shi Y., Seuring S., Koh S.C.L., Blockchain applications in supply chains, transport and logistics: A systematic review of the literature, International Journal of Production Research, 58, 7, pp. 2063-2081, (2020); Ranjbari M., Esfandabadi Z.S., Zanetti M.C., Scagnelli S.D., Siebers P.-O., Aghbashlo M., Peng W., Quatraro F., Tabatabaei M., Three pillars of sustainability in the wake of COVID-19: A systematic review and future research agenda for sustainable development, Journal of Cleaner Production, 297, (2021); Rasoolimanesh S.M., Ramakrishna S., Hall C.M., Esfandiar K., Seyfi S., A systematic scoping review of sustainable tourism indicators in relation to the sustainable development goals, Journal of Sustainable Tourism, 31, 7, pp. 1497-1517, (2023); Saud S., Chen S., Haseeb A., The role of financial development and globalization in the environment: Accounting ecological footprint indicators for selected one-belt-one-road initiative countries, Journal of Cleaner Production, 250, (2020); Shahbaz M., Balsalobre-Lorente D., Sinha A., Foreign direct Investment–CO2 emissions nexus in Middle East and North African countries: Importance of biomass energy consumption, Journal of Cleaner Production, 217, pp. 603-614, (2019); Sharma G.D., Thomas A., Paul J., Reviving tourism industry post-COVID-19: A resilience-based framework, Tourism Management Perspectives, 37, (2021); Singh R., Kumar K., Khan S., A Comprehensive View of Artificial Intelligence (AI)–based Technologies for Sustainable Development Goals (Sdgs), (2024); Sinha A., Sengupta T., Alvarado R., Interplay between technological innovation and environmental quality: Formulating the SDG policies for next 11 economies, Journal of Cleaner Production, 242, (2020); Zafar M.W., Shahbaz M., Hou F., Sinha A., From nonrenewable to renewable energy and its impact on economic growth: The role of research & development expenditures in Asia-Pacific Economic Cooperation countries, Journal of Cleaner Production, 212, pp. 1166-1178, (2019)","","","Springer","","","","","","25233084","","","","English","Sustain. Dev. Goals Ser.","Book chapter","Final","","Scopus","2-s2.0-105006829181" -"Gora K.; Dhingra B.; Yadav M.","Gora, Kapil (58406773400); Dhingra, Barkha (58308911900); Yadav, Mahender (58020106000)","58406773400; 58308911900; 58020106000","A bibliometric study on the role of micro-finance services in micro, small and medium enterprises","2024","Competitiveness Review","34","4","","718","735","17","12","10.1108/CR-11-2022-0174","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163674701&doi=10.1108%2fCR-11-2022-0174&partnerID=40&md5=3ffded61246bf028c0caed5c481211cd","Department of Commerce, Maharshi Dayanand University, Rohtak, India","Gora K., Department of Commerce, Maharshi Dayanand University, Rohtak, India; Dhingra B., Department of Commerce, Maharshi Dayanand University, Rohtak, India; Yadav M., Department of Commerce, Maharshi Dayanand University, Rohtak, India","Purpose: Micro-finance has a significant role in the better performance of micro, small and medium enterprises (MSMEs). This study aims to provide a comprehensive picture of the existing literature on the role of micro-finance and its approaches in MSMEs. Design/methodology/approach: This work performs a bibliometric analysis using a data set of 631 articles collected from the Scopus database. The Bibliometrix R package and Vosviewer are used to conduct performance analysis and scientific mapping. Performance analysis shows the publication trend, key authors, journals and top influential articles. Science mapping through a bibliographic coupling network of documents is prepared to discover the intellectual structure of the field. Findings: This review has identified the four major themes: access to finance and schemes, women empowerment and poverty alleviation, the performance of micro-finance institutions and recent development in micro-financial institutions. With the help of these research themes, the paper also highlights future research agendas. Originality/value: This paper enriches the understanding of the role of micro-finance services in performance of entrepreneurship with the bibliometric review of top contributors. © 2023, Emerald Publishing Limited.","Bibliometric analysis; Content analysis; Micro-credit; Micro-finance; MSMEs","","","","","","Shallu Batra; Maharishi Dayanand University, MDU","The authors acknowledge the support of Shallu Batra, Maharshi Dayanand University, Rohtak, in completing the manuscript. Funding statement: The present research received no specific grant from any of the funding agencies in the public, private or non-profit sectors. Conflict of interest: The authors declare that there is no conflict of interest.","Agarwala V., Maity S., Sahu T.N., Female entrepreneurship, employability and empowerment: impact of the mudra loan scheme, Journal of Developmental Entrepreneurship, 27, 1, (2022); Akter S., Uddin M.H., Tajuddin A.H., Knowledge mapping of microfinance performance research: a bibliometric analysis, International Journal of Social Economics, 48, 3, pp. 399-418, (2021); Allison T.H., McKenny A.F., Short J.C., The effect of entrepreneurial rhetoric on microlending investment: an examination of the warm-glow effect, Journal of Business Venturing, 28, 6, pp. 690-707, (2013); Alvarez S.A., Barney J.B., Entrepreneurial opportunities and poverty alleviation, Entrepreneurship Theory and Practice, 38, 1, pp. 159-184, (2014); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Attanasio O., Augsburg B., De Haas R., Fitzsimons E., Harmgart H., The impacts of microfinance: evidence from joint-liability lending in Mongolia, American Economic Journal: Applied Economics, 7, 1, pp. 90-122, (2015); Banerjee A., Duflo E., Glennerster R., Kinnan C., The miracle of microfinance? Evidence from a randomized evaluation, American Economic Journal: Applied Economics, 7, 1, pp. 22-53, (2015); Banerjee S.B., Jackson L., Microfinance and the business of poverty reduction: critical perspectives from rural Bangladesh, Human Relations, 70, 1, pp. 63-91, (2017); Bartolini M., Bottani E., Grosse E.H., Green warehousing: systematic literature review and bibliometric analysis, Journal of Cleaner Production, 226, pp. 242-258, (2019); Basto M., Pereira J.M., Leite E., Silva A.F., Ferreira M., Impact of microcredit on sustainable development of business, Journal of Security and Sustainability Issues, 10, 1, pp. 203-217, (2020); Batra S., Saini M., Yadav M., Impact of corporate governance on firm risk: a literature review, IUP Journal of Corporate Governance, 21, 3, pp. 39-55, (2022); Batra S., Saini M., Yadav M., Mapping the intellectual structure of corporate governance and ownership structure: a bibliometric analysis, International Journal of Law and Management, 65, 4, (2023); Batra S., Saini M., Yadav M., Aggarwal V., Mapping the intellectual structure and demystifying the research trend of cross listing: a bibliometric analysis, Managerial Finance, 49, 6, (2022); Berg G., Schrader J., Access to credit, natural disasters, and relationship lending, Journal of Financial Intermediation, 21, 4, pp. 549-568, (2012); Berge L.I.O., Bjorvatn K., Tungodden B., Human and financial capital for microenterprise development: evidence from a field and lab experiment, Management Science, 61, 4, pp. 707-722, (2015); Bhatnagar S., Sharma D., Evolution of green finance and its enablers: a bibliometric analysis, Renewable and Sustainable Energy Reviews, 162, (2022); Block J.H., Fisch C., Eight tips and questions for your bibliographic study in business and management research, Management Review Quarterly, 70, 3, pp. 307-312, (2020); Bradley S.W., Mcmullen J.S., Artz K., Simiyu E.M., Capital is not enough: innovation in developing economies, Journal of Management Studies, 49, 4, pp. 684-717, (2012); Brana S., Microcredit: an answer to the gender problem in funding?, Small Business Economics, 40, 1, pp. 87-100, (2013); Brau J.C., Woller G.M., Microfinance: a comprehensive review of the existing literature, The Journal of Entrepreneurial Finance, 9, 1, pp. 1-28, (2004); Brett J.A., We sacrifice and eat less’: the structural complexities of microfinance participation, Human Organization, 65, 1, pp. 8-19, (2006); Bruton G., Khavul S., Siegel D., Wright M., New financial alternatives in seeding entrepreneurship: microfinance, crowdfunding, and peer-to-peer innovations, Entrepreneurship Theory and Practice, 39, 1, pp. 9-26, (2015); Buckley G., Microfinance in Africa: is it either the problem or the solution?, World Development, 25, 7, pp. 1081-1093, (1997); Chakrabarty S., Bass A.E., Institutionalizing ethics in institutional voids: building positive ethical strength to serve women microfinance borrowers in negative contexts, Journal of Business Ethics, 119, 4, pp. 529-542, (2014); Chakrabarty S., Erin Bass A., Comparing virtue, consequentialist, and deontological ethics-based corporate social responsibility: mitigating microfinance risk in institutional voids, Journal of Business Ethics, 126, 3, pp. 487-512, (2015); Chliova M., Brinckmann J., Rosenbusch N., Is microcredit a blessing for the poor? A meta-analysis examining development outcomes and contextual considerations, Journal of Business Venturing, 30, 3, pp. 467-487, (2015); Columba F., Gambacorta L., Mistrulli P.E., Mutual guarantee institutions and small business finance, Journal of Financial Stability, 6, 1, pp. 45-54, (2010); Das S.K., Entrepreneurship through micro finance in North East India: a comprehensive review of existing literature, Information Management and Business Review, 4, 4, pp. 168-184, (2012); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, Journal of Business Research, 133, 1, pp. 285-296, (2021); Dwivedi N.T., Dwivedi A.K., Understanding impact of microcredit on socio-economic status of women micro-entrepreneurs, International Journal of Business and Globalisation, 30, 2, pp. 262-278, (2022); Eck N.J., van Waltman L., How to normalize cooccurrence data? An analysis of some well-known similarity measures, Journal of the American Society for Information Science and Technology, 60, 8, pp. 1635-1651, (2009); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: how great is the impact?, Scientometrics, 105, 3, pp. 1809-1831, (2015); Ferdousi F., Impact of microfinance on sustainable entrepreneurship development, Development Studies Research, 2, 1, pp. 51-63, (2015); Field E., Pande R., Papp J., Rigol N., Does the classic microfinance model discourage entrepreneurship among the poor? Experimental evidence from India, American Economic Review, 103, 6, pp. 2196-2226, (2013); Franck A.K., Factors motivating women’s informal micro-entrepreneurship: experiences from Penang, Malaysia, International Journal of Gender and Entrepreneurship, 4, 1, pp. 65-78, (2012); Gine X., Karlan D.S., Group versus individual liability: short and long term evidence from Philippine microcredit lending groups, Journal of Development Economics, 107, pp. 65-83, (2014); Hanson S., Changing places through women’s entrepreneurship, Economic Geography, 85, 3, pp. 245-267, (2009); Hirsh J.E., An index to quantify an individual’s scientific research output, Proceedings of the National Academy of Sciences, 102, 46, pp. 16569-16572, (2005); Kent D., Dacin M.T., Bankers at the gate: microfinance and the high cost of borrowed logics, Journal of Business Venturing, 28, 6, pp. 759-773, (2013); Khatib S.F.A., Abdullah D.F., Elamer A.A., Abueid R., Nudging toward diversity in the boardroom: a systematic literature review of board diversity of financial institutions, Business Strategy and the Environment, 30, 2, pp. 985-1002, (2021); Khatib S.F.A., Abdullah D.F., Elamer A.A., Yahaya I.S., Owusu A., Global trends in board diversity research: a bibliometric view, Meditari Accountancy Research, 29, 6, pp. 1-34, (2021); Khavul S., Chavez H., Bruton G.D., When institutional change outruns the change agent: the contested terrain of entrepreneurial microfinance for those in poverty, Journal of Business Venturing, 28, 1, pp. 30-50, (2013); Koenigsmarck M., Geissdoerfer M., Mapping socially responsible investing: a bibliometric and citation network analysis, Journal of Cleaner Production, 296, (2021); Kumar S., Pandey N., Marc W., Chatterjee A.N., Pandey N., What do we know about transfer pricing? Insights from bibliometric analysis, Journal of Business Research, 134, pp. 275-287, (2021); Leach F., Sitaram S., Microfinance and women’s empowerment: a lesson from India, Development in Practice, 12, 5, pp. 575-588, (2002); Mader P., Microfinance and financial inclusion, Strategic Change, 29, 3, pp. 257-266, (2016); Madichie N.O., Nkamnebe A.D., Micro-credit for microenterprises?: a study of women ‘petty’ traders in Eastern Nigeria, Gender in Management: An International Journal, 25, 4, pp. 301-319, (2010); Marcillo M., Micro-finance and entrepreneurship in developing countries, International Journal of Business and Applied Sciences, 6, 2, pp. 42-52, (2017); Mayoux L., Women’s empowerment and micro-finance programmes: strategies for increasing impact, Development in Practice, 8, 2, pp. 235-241, (1998); Mersland R., Randoy T., Strom R.O., The impact of international influence on microbanks’ performance: a global survey, International Business Review, 20, 2, pp. 163-176, (2011); Mohiuddin M., Mazumder M.N.H., Al Mamun A., Su Z., Evolution of social microenterprises from rural to the urban area: a study on income-generating micro-entrepreneurs in an urban context, Strategic Change, 29, 4, pp. 435-446, (2020); Mumu J.R., Saona P., Russell H.I., Azad M.A.K., Corporate governance and remuneration: a bibliometric analysis, Journal of Asian Business and Economic Studies, 28, 4, pp. 242-262, (2021); Nagayya D., Rao D.K., Micro finance and support organisations in the Southern states of India, Journal of Rural Development, 28, 3, pp. 285-301, (2009); Nair M., Njolomole M., Microfinance, entrepreneurship and institutional quality, Journal of Entrepreneurship and Public Policy, 9, 1, pp. 137-148, (2020); Omwono G.A., Paul H.J., Effect of microfinance credit on the financial performance of micro, small and medium enterprises in Muhanga district, Rwanda, International Journal of Research in Business and Management, 1, 2, pp. 39-63, (2019); Patil S., Kokate K., Identifying factors governing attitude of rural women towards self-help groups using principal component analysis, Journal of Rural Studies, 55, pp. 157-167, (2017); Premchander S., NGOs and local MFIs-how to increase poverty reduction through women’s small and micro-enterprise, Futures, 35, 4, pp. 361-378, (2003); Pritchard A., Statistical bibliography or bibliometrics, Journal of Documentation, 25, (1969); Raghunathan K., Kannan S., Quisumbing A.R., Can women’s self-help groups improve access to information, decision-making, and agricultural practices? The Indian case, Agricultural Economics United Kingdom, 50, 5, pp. 567-580, (2019); Rajendran K., Micro finance through self-help groups – a survey of recent literature in India, International Journal of Marketing, Financial Services and Management Research, 1, 12, pp. 110-125, (2012); Ranabahu N., Tanima F.A., Empowering vulnerable microfinance women through entrepreneurship: opportunities, challenges and the way forward, International Journal of Gender and Entrepreneurship, 14, 2, pp. 145-166, (2022); Randoy T., Strom R., Mersland R., The impact of entrepreneur-CEOs in microfinance institutions: a global survey, Entrepreneurship Theory and Practice, 39, 4, pp. 927-953, (2015); Ribeiro J.P.C., Duarte F., Gama A.P.M., Does microfinance foster the development of its clients? A bibliometric analysis and systematic literature review, Financial Innovation, 8, 1, (2022); Rogaly B., Micro-finance evangelism, ‘destitute women’, and the hard selling of a new anti-poverty formula, Development in Practice, 6, 2, pp. 100-112, (1996); Roy A., Goswami C., A scientometric analysis of literature on performance assessment of microfinance institutions (1995-2010), International Journal of Commerce and Management, 23, 2, pp. 148-174, (2013); Shabbir M.S., The role of formal academician in promotion of micro-finance, International Journal of Research -Granthaalayah, 4, 5, pp. 35-50, (2016); Shafi M., Liu J., Ren W., Impact of COVID-19 pandemic on micro, small, and medium-sized enterprises operating in Pakistan, Research in Globalization, 2, (2020); Singh S., Chamola P., Kumar V., Verma P., Makkar N., Explaining the revival strategies of Indian MSMEs to mitigate the effects of COVID-19 outbreak, Benchmarking: An International Journal, 30, 1, pp. 121-148, (2023); Singh J., Dutt P., Microfinance and entrepreneurship at the base of the pyramid, Strategic Entrepreneurship Journal, 16, 1, pp. 3-31, (2019); Srivastava M., Sivaramakrishnan S., Mapping the themes and intellectual structure of customer engagement: a bibliometric analysis, Marketing Intelligence and Planning, 39, 5, pp. 702-727, (2021); Tripathi V.K., Micro finance in India- growth, and evolution in India, International Journal of Information, Business and Management, 7, 3, pp. 291-318, (2015); Valdivia M., Karlan D., Teaching entrepreneurship: impact of business training on microfinance clients and institutions, Review of Economics and Statistics, 93, 2, pp. 510-527, (2011); Vanclay J.K., On the robustness of the h-index, Journal of the American Society for Information Science and Technology, 58, 10, pp. 1-10, (2007); Yadav M., Saini M., Environmental, social and governance literature: a bibliometric analysis, International Journal of Managerial and Financial Accounting, 15, 2, pp. 231-254, (2023); Yadav M., Gora K., Dahiya J., Problems faced by micro, small, and medium enterprises: a review, IUP Journal of Entrepreneurship Development, 19, 1, (2022); Yunus M., Banker to the Poor, (1998); Zhao E.Y., Lounsbury M., An institutional logics approach to social entrepreneurship: market logic, religious diversity, and resource acquisition by micro finance organizations, Journal of Business Venturing, 31, 6, pp. 643-662, (2016)","K. Gora; Department of Commerce, Maharshi Dayanand University, Rohtak, India; email: kapil.rs.comm@mdurohtak.ac.in; B. Dhingra; Department of Commerce, Maharshi Dayanand University, Rohtak, India; email: dhingrabarkha1611@gmail.com","","Emerald Publishing","","","","","","10595422","","","","English","Compet. Rev.","Review","Final","","Scopus","2-s2.0-85163674701" -"Basumatary B.; Verma M.K.","Basumatary, Bwsrang (57992264800); Verma, Manoj Kumar (57190839871)","57992264800; 57190839871","Cluster Analysis and Network Visualization of Social Work Research: A Scientometric Mapping","2024","Journal of Indian Library Association","60","2","","172","192","20","0","","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105004808964&partnerID=40&md5=eb2673b8c7a8e78ab972c369eed974f7","Dept. of Library and Information Science, Mizoram University, Aizawl, 796004, India","Basumatary B., Dept. of Library and Information Science, Mizoram University, Aizawl, 796004, India; Verma M.K., Dept. of Library and Information Science, Mizoram University, Aizawl, 796004, India","Social work research is the application of research approaches to solve social issues in society. This study examines growth and trends in social work research reflected in two leading journals, the Indian Journal of Social Work (IJSW) and the British Journal of Social Work (BJSW). The purpose of this study was to analyze the research growth trends, performance of authors, organizations, and scientific mapping of the research publications in both journals. The study acquired 489 data from IJSW and 1617 data from BJSW from the Scopus database and employed performance measurement and science mapping techniques using scientometric tools. The study used MS Excel and OriginPro 9.0 to analyze the chronological growth trends of publications. VOSviewer and Biblioshiny (Bibliometrix R package) were used for network analysis and visualization. The findings indicate un-uniformity in the publication productivity of both journals, and BJSW published more collaborative research than IJSW. Researchers who communicated with IJSW are mainly from the Tata Institute of Social Sciences (India). Queen's University Belfast (UK) is the most prolific organization associated with BJSW. Articles related to Covid-19, Social work, Children, etc., appeared most frequently in the IJSW, whereas Child protection, Ethnicity, and social work education appeared most frequently in the BJSW. The relationships between research topics, countries, and affiliations of researchers are assessed. In conclusion, directions for further research are also suggested. © 2024, Indian Library Association. All rights reserved.","BJSW; Cluster Analysis; IJSW; Network Visualization; Scientometrics; Social Work Research","","","","","","","","Aria M., Cuccurullo C., Bibliomertrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Basumatary B., Verma A. K., Kushwaha S., Verma M. K., Global research trends and performance measurement on biofloc technology (BFT): a systematic review based on computational techniques, Aquaculture International, 32, 1, pp. 215-240, (2024); Batcha M. S., Ahmad M., Publication Trend in an Indian Journal and a Pakistan Journal: A Comparative Analysis using Scientometric Approach, Journal of Advances in Library and Information Science, 6, 4, pp. 442-449, (2017); About the journal, The British Journal of Social Work, (2022); Borgohain D. J., Zakariab S., Verma M. K., Cluster Analysis and Network Visualization of Global Research on Digital Libraries during 2016–2020: A Bibliometric Mapping, Science & Technology Libraries, (2021); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of business research, 133, pp. 285-296, (2021); Eck N.J.V., Waltman L., VOSviewer Manual, (2019); Garfield E., Citation analysis as a tool in journal evaluation: Journals can be ranked by frequency and impact of citations for science policy studies, Science, 178, 4060, pp. 471-479, (1972); Jill Manthorpe, Google Scholar Profile, (2022); Hirsch J., An index to quantify an individual’s scientific research output, Proceedings of the National Academy of Sciences, 102, pp. 16569-16572, (2005); The Indian Journal of Social Work, (2022); Kolle S.R., Gaddimani P., Scholarly Communication in the Indian Journal of Social Work: A bibliometric study, International Journal of Information Dissemination and Technology, 6, 3, pp. 234-236, (2016); Lihitkar R. S., Patil V. B., Content Analysis of Special Issues of Indian Journal of Social Work (2001-2012), American International Journal of Research in Humanities. Arts and Social Sciences, 22, 1, pp. 226-232, (2018); Nalimov V.V., Mulchenko Z.M., Measurement of Science: Study of the Development of science as an information process, pp. 1-191, (1969); Noyons E.C.M., Moed H.F., van Raan A.F.J., Integrating research performance analysis and science mapping, Scientometrics, 46, pp. 591-604, (1999); Patralekh M. K., Vaish A., Vaishya R., Gulia A., Lal H., Trends of publication in the orthopedic journals from India: A bibliometric analysis, Indian Journal of Medical Sciences, 73, 1, pp. 134-140, (2021); Paul J., Bhukya R., Forty-five years of International Journal of Consumer Studies: A bibliometric review and directions for future research, International Journal of Consumer Studies, 45, pp. 937-963, (2021); So K. K. F., Kim H., King C., The thematic evolution of customer engagement research: a comparative systematic review and bibliometric analysis, International Journal of Contemporary Hospitality Management, 33, 10, pp. 3585-3609, (2021); Surwase G., Sagar A., Kademani B.S., Bhanumurthy K., Co-citation Analysis: An Overview, Beyond Librarianship: Creativity, Innovation and Discovery. Conference proceedings of the Bombay Science Librarian Association, (2011); The Indian Journal of Social Work: An Overview, (2022)","M.K. Verma; Dept. of Library and Information Science, Mizoram University, Aizawl, 796004, India; email: manojdlis@mzu.edu.in","","Indian Library Association","","","","","","22775145","","","","English","J. Indian Library Assoc.","Article","Final","","Scopus","2-s2.0-105004808964" -"Shandilya A.K.; Kumar D.","Shandilya, Abhinav Kumar (58079894200); Kumar, Dilip (59116291900)","58079894200; 59116291900","Adoption of virtual reality and augmented reality in the hotel industry","2024","Hotel and Travel Management in the AI Era","","","","1","18","17","1","10.4018/979-8-3693-7898-4.ch001","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105007127301&doi=10.4018%2f979-8-3693-7898-4.ch001&partnerID=40&md5=7aa5675ef3c355731ebca4df49c1aba8","Birla Institute of Technology, India; Manipal Academy of Higher Education, India","Shandilya A.K., Birla Institute of Technology, India; Kumar D., Manipal Academy of Higher Education, India","A bibliometric study using Bibliometrix R-package was conducted to determine the answers to publication and citation trends, the author's contributions and collaboration patterns, the most relevant sources and their impact, and the major clusters' evolution. 57 articles were identified since 1996 for the final analysis. After the pandemic (COVID-19), publication trends have grown, and citation trends have also shown upward and downward over time. The collaborative author's work has increased drastically, indicating the quality of the published articles. Mostly Q1 quality journals appeared in the top 10 most influential sources, which shows the popularity of this theme growing recently. Science mapping using bibliographic coupling analysis was performed and generated seven clusters such as Evacuation behaviour in hotel building using a virtual environment, User engagement in the virtual world of hotels, VR's impact on hotels, VR in hotel marketing and customer engagement, Harnessing VR and AR in Hospitality, and Traveller experience. © 2024, IGI Global.","","Bibliographic retrieval systems; Bibliographic couplings; Bibliometric; Collaboration patterns; Coupling analysis; Hotel building; Hotel industry; User engagement; Virtual worlds; Virtualization","","","","","","","Ahn J.C., Cho S.P., Jeong S.K., Virtual reality to help relieve travel anxiety, KSII Transactions on Internet and Information Systems, 7, 6, pp. 1443-1448, (2013); Ahn J.C., Lee O., Alleviating travel anxiety through virtual reality and narrated video technology, Bratislava Medical Journal, 114, 10, pp. 595-602, (2013); Alfaro L., Rivera C., Luna-Urquizo J., Arroyo-Paz A., Delgado L., Castaneda E., Experiential Marketing Tourism and Hospitality Tours Generation Hybrid Model, MENDEL-Soft Computing Journal, 29, 2, pp. 2571-3701, (2023); Alfaro L., Rivera C., Suarez E., Raposo A., 360° Virtual Reality Video Tours Generation Model for Hostelry and Tourism based on the Analysis of User Profiles and Case-based Reasoning., In IJACSA International Journal of Advanced Computer Science and Applications, 13, 11, (2022); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Baker H.K., Kumar S., Pandey N., Kraus S., Contemporary Accounting Research: A Retrospective between 1984 and 2021 using Bibliometric Analysis, Contemporary Accounting Research, 40, 1, pp. 196-230, (2023); Bilgihan A., Ricci P., The new era of hotel marketing: Integrating cuttingedge technologies with core marketing principles, Journal of Hospitality and Tourism Technology, 15, 1, pp. 123-137, (2024); Bogicevic V., Liu S.Q., Seo S., Kandampully J., Rudd N.A., Virtual reality is so cool! How technology innovativeness shapes consumer responses to service preview modes, International Journal of Hospitality Management, 93, (2021); Bogicevic V., Seo S., Kandampully J.A., Liu S.Q., Rudd N.A., Virtual reality presence as a preamble of tourism experience: The role of mental imagery, Tourism Management, 74, pp. 55-64, (2019); Chawla R.N., Goyal P., Emerging trends in digital transformation: A bibliometric analysis, Benchmarking, 29, 4, pp. 1069-1112, (2022); SCOPUS: Your brilliance, connected, (2020); Scopus, (2024); Flavian C., Ibanez-Sanchez S., Orus C., Impacts of technological embodiment through virtual reality on potential guests' emotions and engagement, Journal of Hospitality Marketing & Management, 30, 1, pp. 1-20, (2021); Grinberg A.M., Careaga J.S., Mehl M.R., O'Connor M.-F., Social engagement and user immersion in a socially based virtual world, Computers in Human Behavior, 36, pp. 479-486, (2014); Huang Y.C., Backman S.J., Backman K.F., Moore D.W., Exploring user acceptance of 3D virtual worlds in travel and tourism marketing, Tourism Management, 36, pp. 490-501, (2013); Israel K., Tscheulin D.K., Zerres C., Virtual reality in the hotel industry: assessing the acceptance of immersive hotel presentation, In European Journal of Tourism Research, (2019); Israel K., Zerres C., Tscheulin D.K., Presenting hotels in virtual reality: Does it influence the booking intention?, Journal of Hospitality and Tourism Technology, 10, 3, pp. 473-493, (2019); Jose de Oliveira O., Francisco da Silva F., Juliani F., Cesar Ferreira Motta Barbosa L., Vieira Nunhes T., Bibliometric Method for Mapping the Stateof-the-Art and Identifying Research Gaps and Trends in Literature: An Essential Instrument to Support the Development of Scientific Projects, In Scientometrics Recent Advances. IntechOpen, (2019); Kleminski R., Kazienko P., Kajdanowicz T., Analysis of direct citation, co-citation and bibliographic coupling in scientific topic identification, Journal of Information Science, 48, 3, pp. 349-373, (2022); Kumar D., Choudhuri S., Shandilya A.K., Singh R., Tyagi P., Singh A.K., Food Waste & Sustainability Through A Lens of Bibliometric Review: A Step Towards Achieving SDG 2030, 2022 International Conference on Innovations in Science and Technology for Sustainable Development (ICISTSD), pp. 185-192, (2022); Kumar D., Shandilya A.K., Varghese S.G., Mapping Sustainable Cities and Communities (SDG 11) Research: A Bibliometric Review, Sdg, 11, pp. 1-9, (2023); Lazarides M.K., Lazaridou I.-Z., Papanas N., Bibliometric Analysis: Bridging Informatics With Science, The International Journal of Lower Extremity Wounds, (2023); Lee O., Ahn J., Embedded Virtual Reality for Travel Security, 2012 International Conference on Information Science and Applications, pp. 1-6, (2012); Lee O., Oh J.-E., The Impact of Virtual Reality Functions of a Hotel Website on Travel Anxiety, Cyberpsychology & Behavior, 10, 4, pp. 584-586, (2007); Leung X.Y., Lyu J., Bai B., A fad or the future?, Examining the effectiveness of virtual reality advertising in the hotel industry. International Journal of Hospitality Management, 88, (2020); Lim W.M., Kumar S., Pandey N., Verma D., Kumar D., Evolution and trends in consumer behaviour: Insights from Journal of Consumer Behaviour, Journal of Consumer Behaviour, 22, 1, pp. 217-232, (2023); Lim W.M., Mohamed Jasim K., Das M., Augmented and virtual reality in hotels: Impact on tourist satisfaction and intention to stay and return, International Journal of Hospitality Management, 116, (2024); Lo W.H., Cheng K.L.B., Does virtual reality attract visitors? The mediating effect of presence on consumer response in virtual reality tourism advertising, Information Technology & Tourism, 22, 4, pp. 537-562, (2020); Lyu J., Leung X., Bai B., Stafford M., Hotel virtual reality advertising: a presence-mediated model and gender effects, Journal of Hospitality and Tourism Technology, (2021); Ma T.-J., Lee G.-G., Liu J., Lae R., Bibliographic coupling: A main path analysis from 1963 to 2020, Information Research, 27, 1, (2022); Mantymaki M., Riemer K., Digital natives in social virtual worlds: A multi-method study of gratifications and social influences in Habbo Hotel, International Journal of Information Management, 34, 2, pp. 210-220, (2014); Mantymaki M., Salo J., Purchasing behavior in social virtual worlds: An examination of Habbo Hotel, International Journal of Information Management, 33, 2, pp. 282-290, (2013); Mateas M., Lewis S., A MOO-based virtual training environment, Journal of Computer-Mediated Communication, 2, 3, (1996); McKiernan G., Bibliometrics, Cybermetrics, Informetrics, and Scientometrics Sites and Sources, Science & Technology Libraries, 26, 2, pp. 107-115, (2005); Meng F., Zhang W., Way-finding during a fire emergency: An experimental study in a virtual environment, Ergonomics, 57, 6, pp. 816-827, (2014); Najam Z., Nisar Q.A., Hussain K., Nasir S., Enhancing Employer Branding through Virtual Reality: The role of E-HRM Service Quality and HRM Effectiveness in the Hotel Industry of Pakistan, Asia-Pacific Journal of Innovation in Hospitality and Tourism, 11, 2, (2022); Orus C., Ibanez-Sanchez S., Flavian C., Enhancing the customer experience with virtual and augmented reality: The impact of content and device type, International Journal of Hospitality Management, 98, (2021); Pijls R., Galetzka M., Groen B.H., Pruyn A.T.H., Come in please: A virtual reality study on entrance design factors influencing the experience of hospitality, Journal of Environmental Psychology, 90, (2023); Scimago Journal & Country Rank, (2024); Siamionava K., Slevitch L., Tomas S.R., Effects of spatial colors on guests' perceptions of a hotel room, International Journal of Hospitality Management, 70, pp. 85-94, (2018); Slevitch L., Chandrasekera T., Mejia-Puig L., Korneva K., Akosa J.S., Virtual Reality images' impact on cognition and affect in hotel promotions: Application of self-reported and psycho-physiological measures, Journal of Hospitality and Tourism Management, 53, pp. 176-187, (2022); Slevitch L., Chandrasekera T., Sealy M.D., Comparison of Virtual Reality Visualizations With Traditional Visualizations in Hotel Settings, Journal of Hospitality & Tourism Research (Washington, D.C.), 46, 1, pp. 212-237, (2022); Snopkova D., Ugwitz P., Stachon Z., Hladik J., Jurik V., Kvarda O., Kubicek P., Retracing evacuation strategy: A virtual reality game-based investigation into the influence of building's spatial configuration in an emergency, Spatial Cognition and Computation, 22, 1-2, pp. 30-50, (2022); Surovaya E., Prayag G., Yung R., Khoo-Lattimore C., Telepresent or not? Virtual reality, service perceptions, emotions and post-consumption behaviors, Anatolia, 31, 4, pp. 620-635, (2020); Vilar E., Rebelo F., Noriega P., Duarte E., Mayhorn C.B., Effects of competing environmental variables and signage on route-choices in simulated everyday and emergency wayfinding situations, Ergonomics, 57, 4, pp. 511-524, (2014); Vilar E., Rebelo F., Noriega P., Teles J., Mayhorn C., Signage versus environmental affordances: Is the explicit information strong enough to guide human behavior during a wayfinding task?, Human Factors and Ergonomics in Manufacturing, 25, 4, pp. 439-452, (2015); Yoon S., Erdem M., Schuckert M., Lee P.C., Revisiting the impact of VR applications on hotel bookings, Journal of Hospitality and Tourism Technology, 12, 3, pp. 489-511, (2021); Zeng G., Cao X., Lin Z., Xiao S.H., When online reviews meet virtual reality: Effects on consumer hotel booking, Annals of Tourism Research, 81, (2020)","","","IGI Global","","","","","","","979-836937900-4; 979-836937898-4","","","English","Hotel and Travel Manag. in the AI Era","Book chapter","Final","","Scopus","2-s2.0-105007127301" -"Wani J.A.; Ganaie S.A.","Wani, Javaid Ahmad (57211168037); Ganaie, Shabir Ahmad (55745889700)","57211168037; 55745889700","The scientific outcome in the domain of grey literature: bibliometric mapping and visualisation using the R-bibliometrix package and the VOSviewer","2024","Library Hi Tech","42","1","","309","330","21","13","10.1108/LHT-01-2022-0012","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144168530&doi=10.1108%2fLHT-01-2022-0012&partnerID=40&md5=9ac84e262bba0ab5fdde8e8fa42bfb17","Department of Library and Information Science, University of Kashmir, Srinagar, India","Wani J.A., Department of Library and Information Science, University of Kashmir, Srinagar, India; Ganaie S.A., Department of Library and Information Science, University of Kashmir, Srinagar, India","Purpose: The current study aims to map the scientific output of grey literature (GL) through bibliometric approaches. Design/methodology/approach: The source for data extraction is a comprehensive “indexing and abstracting” database, “Web of Science” (WOS). A lexical title search was applied to get the corpus of the study – a total of 4,599 articles were extracted for data analysis and visualisation. Further, the data were analysed by using the data analytical tools, R-studio and VOSViewer. Findings: The findings showed that the “publications” have substantially grown up during the timeline. The most productive phase (2018–2021) resulted in 47% of articles. The prominent sources were PLOS One and NeuroImage. The highest number of papers were contributed by Haddaway and Kumar. The most relevant countries were the USA and UK. Practical implications: The study is useful for researchers interested in the GL research domain. The study helps to understand the evolution of the GL to provide research support further in this area. Originality/value: The present study provides a new orientation to the scholarly output of the GL. The study is rigorous and all-inclusive based on analytical operations like the research networks, collaboration and visualisation. To the best of the authors' knowledge, this manuscript is original, and no similar works have been found with the research objectives included here. © 2022, Emerald Publishing Limited.","Bibliometrics; Citation analysis; Grey literature; Science mapping; Scientometrics; VOSviewer","","","","","","","","Adams J., The fourth age of research, Nature, 497, pp. 557-560, (2013); Adams R.J., Smart P., Huff A.S., Shades of grey: guidelines for working with the grey literature in systematic reviews for management and organizational studies, International Journal of Management Reviews, 19, 4, pp. 432-454, (2016); Aghakhani N., Lagzian F., Hazarika B., The role of personal digital library in supporting research collaboration, Electronic Library, 31, 5, pp. 548-560, (2013); Akintunde T.Y., Musa T.H., Musa H.H., Musa I.H., Chen S., Ibrahim E., Helmy M.S.E.D.M., Bibliometric analysis of global scientific literature on effects of COVID-19 pandemic on mental health, Asian Journal of Psychiatry, 63, (2021); Aksnes D.W., Langfeldt L., Wouters P., Citations, citation indicators, and research quality: an overview of basic concepts and theories, Sage Open, 9, 1, pp. 1-17, (2019); Alam S., Zardari S., Shamsi J., Comprehensive three-phase bibliometric assessment on the blockchain (2012-2020), Library Hi Tech, ahead-of-print, (2022); Andrew A.M., Why the world is grey, Grey Systems: Theory and Application, 1, 2, pp. 112-116, (2011); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Auger C.P., Use of Reports Literature, (1975); Auger C.P., Information Sources in Grey Literature. 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Siwach A.K., Parmar S., Research contributions of CCS Haryana agricultural university, Hisar: a bibliometric analysis, DESIDOC Journal of Library and Information Technology, 38, 5, pp. 334-341, (2018); Smedley J., Enhancing information impact: how do we make the most of our information senses?, Information and Learning Sciences, 119, 3-4, pp. 142-144, (2018); Smith M.J., Weinberger C., Bruna E.M., Allesina S., The scientific impact of nations: journal placement and citation performance, PLoS One, 9, 10, (2014); Sulaiman M.H., Mustaffa Z., Mohamed M.R., Aliman O., Using the gray wolf optimizer for solving optimal reactive power dispatch problem, Applied Soft Computing, 32, pp. 286-292, (2015); Sweileh W.M., Global research activity on e-learning in health sciences education: a bibliometric analysis, Medical Science Educator, 31, 2, pp. 765-775, (2021); Tillett S., Newbold E., Grey literature at the British Library: revealing a hidden resource, Interlending and Document Supply, 34, 2, pp. 70-73, (2006); Turner A.M., Liddy E.D., Bradley J., Wheatley J.A., Modeling public health interventions for improved access to the gray literature, Journal of the Medical Library Association, 93, 4, pp. 487-494, (2005); Van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Van Eck N.J., Waltman L., Visualizing bibliometric networks, Measuring Scholarly Impact, (2014); Wani J.A., Ganaie S.A., Rehman I.U., Mapping research output on library and information science research domain in South Africa: a bibliometric visualisation, Information Discovery, ahead-of-print, (2022); Xuemei L., Cao Y., Wang J., Dang Y., Kedong Y., A summary of grey forecasting and relational models and its applications in marine economics and management, Marine Economics and Management, 2, 2, pp. 87-113, (2019); Yang L., Chen Z., Liu T., Gong Z., Yu Y., Wang J., Global trends of solid waste research from 1997 to 2011 by using bibliometric analysis, Scientometrics, 96, 1, pp. 133-146, (2013); Yu D., Xu Z., Pedrycz W., Wang W., Information sciences 1968-2016: a retrospective analysis with text mining and bibliometric, Information Sciences, 418, pp. 619-634, (2017); Zeinoun P., Akl E.A., Maalouf F.T., Meho L.I., The Arab region's contribution to global mental health research (2009-2018): a bibliometric analysis, Frontiers in Psychiatry, 11, (2020)","J.A. Wani; Department of Library and Information Science, University of Kashmir, Srinagar, India; email: wanijavaid1@gmail.com","","Emerald Publishing","","","","","","07378831","","","","English","Libr. Hi Tech","Article","Final","","Scopus","2-s2.0-85144168530" -"Wardiman B.; Natsir A.; Syahrir S.","Wardiman, Budi (58393549900); Natsir, Asmuddin (8290761000); Syahrir, Syahriani (56664515500)","58393549900; 8290761000; 56664515500","Bibliometric Analysis of Trends and Future Research Directions in Protected Fat Supplementation in Ruminant Nutrition","2024","International Journal of Design and Nature and Ecodynamics","19","5","","1591","1602","11","0","10.18280/ijdne.190513","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207961848&doi=10.18280%2fijdne.190513&partnerID=40&md5=4cfb733ad56931a3be0c23b441c788a0","Department of Agricultural Science, Hasanuddin University, Makassar, 90245, Indonesia; Department of Nutrition and Animal Feed, Faculty of Animal Husbandry, Hasanuddin University, Makassar, 90245, Indonesia","Wardiman B., Department of Agricultural Science, Hasanuddin University, Makassar, 90245, Indonesia; Natsir A., Department of Nutrition and Animal Feed, Faculty of Animal Husbandry, Hasanuddin University, Makassar, 90245, Indonesia; Syahrir S., Department of Nutrition and Animal Feed, Faculty of Animal Husbandry, Hasanuddin University, Makassar, 90245, Indonesia","Rumen protected fat (RPF) has garnered significant attention in livestock nutrition research. The present study aimed to perform a bibliometric analysis on RPF research in ruminant nutrition to evaluate global research patterns and future trends. This study represents the first bibliometric analysis on this topic using data from Scopus database to examine publications from 1991 to july 2024. The bibliometric analysis was done using Scopus Bibliometrix and VOSviewer. We identified 148 relevant articles, with a noticeable increase in publications starting around 2006, peaking notably in 2019 and 2020. The Journal of Dairy Science emerged as the leading publisher in this field. M. Kreuzer was identified as the most prolific author. Cluster analysis revealed five main thematic areas: (1) dairy cow and physiology; (2) meat production and performance; (3) rumen fermentation and digestibility; (4) buffalo-specific studies; and (5) forage management. Notably, the application of RPF in large ruminants primarily focused on milk production and quality, while in small ruminants, it mainly addressed performance, carcass traits, and meat quality. Future research should explore under-studied areas such as meat quality, genetic expression, and performance in large ruminants, and on milk quality and production in small ruminants. ©2024 The authors.","bibliometric analysis; citation analysis; co-occurrence analysis; coaccurance analysis; rumen inert fat; rumen protected fat; science mapping; VOSviewer","","","","","","Universitas Hasanuddin","This study was funded by Hasanuddin University.","Jenkins T.C., Symposium: Advances in ruminant lipid metabolism: Lipid metabolism in the rumen, Journa of Dairy Science, 76, 12, pp. 3851-3863, (1992); Palmquist D.L., Jenkins T.C., A 100-Year Review: Fat feeding of dairy cows, Journal of Dairy Science, 100, 12, pp. 10061-10077, (2017); Shingfield K.J., Ahvenjarvi S., Toivonen V., Arola A., Nurmela K.V.V., Huhtanen P., Griinari J.M., Effect of dietary fish oil on biohydrogenation of fatty acids and milk fatty acid content in cows, Animal Science, 77, 1, pp. 165-179, (2003); Kim T.B., Lee J.S., Cho S.Y., Lee H.G., In vitro and in vivo studies of rumen-protected microencapsulated supplement comprising linseed oil, vitamin e, rosemary extract, and hydrogenated palm oil on rumen fermentation, physiological profile, milk yield, and milk composition in dairy cows, Animals, 10, 9, (2020); Weiss W.P., Wyatt D.J., Digestible energy values of diets with different fat supplements when fed to lactating dairy cows, Journal of Dairy Science, 87, 5, pp. 1446-1454, (2004); Jiao P., Wang Z., Zhang X., Lu X., Sun Q., Zhao H., Hou Y., Dietary supplementation of Clostridium butyricum and rumen protected fat alters immune responses, rumen fermentation, and bacterial communities of goats, Animal Feed Science and Technology, 314, (2024); Miranda A.S., Andrade M.A., Nascimento K.B., Santos T.G., Lessa M.B., Gomes D.I., Gionbelli M.P., Effect of supplementing rumen-protected fat during the second half of gestation on maternal performance and metabolism in ewes during pregnancy and subsequent lactation, Animal Feed Science and Technology, 304, (2023); Ismail A., Muhammad A.I., Kee L.T., Chwen L.T., Samsudin A.A., Effects of rumen-protected fat on changes of metabolites and reproductive genes in testes of Malin rams, Journal of the Indonesian Tropical Animal Agriculture, 48, 2, pp. 76-88, (2023); Farrag B., El-Bahrawy K.A., Shedeed H.A., El-Rayes M.A.H., Effect of protected fatty acid supplementation on ovarian activity, reproductive hormone profiles and reproduction of Barki ewes under semiarid conditions, Archives Animal Breeding, 67, 1, pp. 111-122, (2024); Ramirez-Zamudio G.D., da Cruz W.F., Schoonmaker J.P., de Resende F.D., Siqueira G.R., Neto O.R.M., Ladeira M.M., Effect of rumen-protected fat on performance, carcass characteristics and beef quality of the progeny from Nellore cows fed by different planes of nutrition during gestation, Livestock Science, 258, (2022); da Silva A.P.V., Dias A.M., Itavo L.C.V., Itavo C.C.B.F., de Nadai Bonin Gomes M., Nogueira E., Junges L., The influence of protected fat in supplements on the performance and carcass characteristics of Nellore beef bulls in tropical pasture, Tropical Animal Health and Production, 54, 2, (2022); Gumus H., Oguz F.K., Mustafa O.G.U.Z., Bugdayci K.E., Dagli H., Effects of replacing grain feed with rumen-protected fat on feedlot performance, ruminal parameters and blood metabolites in growing Merinos lambs’ diets during the hot season, Ankara Üniversitesi Veteriner Fakültesi Dergisi, 69, 2, pp. 131-138, (2022); El-Zaiat H.M., Mohamed D., Sallam S.M., Palmitic acid-enriched fat supplementation alleviates negative production responses during early lactation of Holstein dairy cows, Animal Production Science, 60, 13, pp. 1598-1606, (2020); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, pp. 1809-1831, (2015); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Ozturk O., Kocaman R., Kanbach D.K., How to design bibliometric research: An overview and a framework proposal, Review of Managerial Science, 18, pp. 3333-3361, (2024); Singh V.K., Singh P., Karmakar M., Leta J., Mayr P., The journal coverage of Web of Science, Scopus and Dimensions: A comparative analysis, Scientometrics, 126, pp. 5113-5142, (2021); Li J., Burnham J.F., Lemley T., Britton R.M., Citation analysis: Comparison of web of science®, scopus™, SciFinder®, and google scholar, Journal of Electronic Resources in Medical Libraries, 7, 3, pp. 196-217, (2010); Gavel Y., Iselid L., Web of Science and Scopus: A journal title overlap study, Online Information Review, 32, 1, pp. 8-21, (2008); Mongeon P., Paul-Hus A., The journal coverage of Web of Science and Scopus: A comparative analysis, Scientometrics, 106, pp. 213-228, (2016); Mafruchati M., Ismail W.I.W., Wardhana A.K., Fauzy M.Q., Bibliometric analysis of veterinary medicine on embryo of animals in textbook in conceptualizing disease and health, Heliyon, 9, 6, (2023); Kirby A., Exploratory bibliometrics: using VOSviewer as a preliminary research tool, Publications, 11, 1, (2023); Van Eck N.J., Waltman L., Dekker R., Van Den Berg J., A comparison of two techniques for bibliometric mapping: Multidimensional scaling and VOS, Journal of the American Society for Information Science and Technology, 61, 12, pp. 2405-2416, (2010); Alstrup L., Nielsen M.O., Lund P., Sehested J., Larsen M.K., Weisbjerg M.R., Milk yield, feed efficiency and metabolic profiles in Jersey and Holstein cows assigned to different fat supplementation strategies, Livestock Science, 178, pp. 165-176, (2015); Frank E., Livshitz L., Portnick Y., Kamer H., Alon T., Moallem U., The effects of high-fat diets from calcium salts of palm oil on milk yields, rumen environment, and digestibility of high-yielding dairy cows fed low-forage diet, Animals, 12, 16, (2022); Ganjkhanlou M., Rezayazdi K., Ghorbani G.R., Banadaky M.D., Morraveg H., Yang W.Z., Effects of protected fat supplements on production of early lactation Holstein cows, Animal Feed Science and Technology, 154, 3-4, pp. 276-283, (2009); Kirovski D., Blond B., Katic M., Markovic R., Sefer D., Milk yield and composition, body condition, rumen characteristics, and blood metabolites of dairy cows fed diet supplemented with palm oil, Chemical and Biological Technologies in Agriculture, 2, (2015); Nam I.S., Choi J.H., Seo K.M., Ahn J.H., In vitro and lactation responses in mid-lactating dairy cows fed protected amino acids and fat, Asian-Australasian Journal of Animal Sciences, 27, 12, pp. 1705-1711, (2014); Chavda M., Savsani H., Karangiya V., Gamit V., Ribadiya N., Fefar D., Dodiya P., Influence of peripartum dietary supplementation of choline and fat in protected form on production performance of Gir cows, The Indian Journal of Animal Sciences, 94, 2, pp. 148-153, (2024); Lohrenz A.K., Duske K., Schneider F., Nurnberg K., Losand B., Seyfert H.M., Hammon H.M., Milk performance and glucose metabolism in dairy cows fed rumen-protected fat during mid lactation, Journal of Dairy Science, 93, 12, pp. 5867-5876, (2010); Alba H.D., Freitas Junior J.E.D., Leite L.C., Azevedo J.A., Santos S.A., Pina D.S., Carvalho G.G.D., Protected or unprotected fat addition for feedlot lambs: Feeding behavior, carcass traits, and meat quality, Animals, 11, 2, (2021); Zdorovieva E., Boryaev G., Kistanova E., Nosov A., Fedorov Y., Semigodov N., Protected fat in the diet of lactating ewes affects milk composition, lamb body weight and their biochemical parameters, Bulgarian Journal of Agricultural Science, 25, 6, pp. 1277-1280, (2019); Bhatt R.S., Karim S.A., Sahoo A., Shinde A.K., Growth performance of lambs fed diet supplemented with rice bran oil as such or as calcium soap, Asian-Australasian journal of animal sciences, 26, 6, pp. 812-819, (2013); Zhang M., Zhang Z., Zhang X., Lu C., Yang W., Xie X., Jiao P., Effects of dietary Clostridium butyricum and rumen protected fat on meat quality, oxidative stability, and chemical composition of finishing goats, Journal of Animal Science and Biotechnology, 15, 1, (2024); Ahmad M.H., Chwen L.T., Maidin M.S., Samsudin A.A., Effect of different forms of rumen-protected fat from palm oil on body weight and sperm quality in Malin sheep, Malaysian Journal of Animal Science, 24, 1, pp. 64-75, (2021); Ahmad N., Shahid M.Q., Haque M.N., Mohsin I., Effect of bypass fat on growth and body condition score of male Beetal goats during summer, South African Journal of Animal Science, 49, 5, pp. 810-814, (2019)","A. Natsir; Department of Nutrition and Animal Feed, Faculty of Animal Husbandry, Hasanuddin University, Makassar, 90245, Indonesia; email: asmuddin_natsir@unhas.ac.id","","International Information and Engineering Technology Association","","","","","","17557437","","","","English","Int. J. Des. Nat. ecodyn.","Article","Final","","Scopus","2-s2.0-85207961848" -"Kabakuş N.","Kabakuş, Nuriye (44661387900)","44661387900","Bibliometric analysis and research trend of sustainable green transportation; [Sürdürülebilir yeşil ulaşımın araştırma eğilimi ve bibliyometrik analizi]","2024","Gumushane Universitesi Fen Bilimleri Dergisi","14","1","","353","369","16","0","10.17714/gumusfenbil.1318232","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105004059451&doi=10.17714%2fgumusfenbil.1318232&partnerID=40&md5=e6244d71fe0e9af08e268d2c242f68de","Ataturk University, Faculty of Applied Sciences, Department of Emergency and Disaster Management, Erzurum, 25240, Turkey","Kabakuş N., Ataturk University, Faculty of Applied Sciences, Department of Emergency and Disaster Management, Erzurum, 25240, Turkey","In recent years, the concept of green transportation has rapidly entered our lives with the increasing awareness of environmental problems such as climate change, air pollution and depletion of natural resources. Green transportation has become a new scientific research area under the umbrella of sustainability due to its benefits to both the economy and the environment. The aim of this study is to provide a common quantitative and qualitative understanding of the overall evolutionary trend, knowledge structure and literature gaps of the sustainable and green transportation (S>) research field. For this purpose, the Bibliometrix library provided by R software was used to analyze S>-related scientific research in the Web of Science database. In this study, using the science mapping approach, a total of 2018 publications published from 1997 to 2022 were analyzed and synthesized in detail. In addition, visualized statistics on the number of publications, citations, prominent authors, institutions, countries, sources, keywords and research themes in the field of S> were analyzed bibliographically. The analysis results show that China is the largest contributing country; Changan University is the most influential institution; Zhang L. is the most influential writer; Sustainability Journal is the primary publishing platform, in the S> field. The results are expected to guide researchers interested in S> issues to identify research gaps. In conclusion, the findings systematically describe the current state of play, key issues and academic frontiers in the field of S>. © 2024, Gumushane University. All rights reserved.","Bibliometric analysis; Green transportation; Sustainable transportation; Web of science","","","","","","","","Alonso D. M., Bond J. Q., Dumesic J. A., Catalytic conversion of biomass to biofuels, Green chemistry, 12, 9, pp. 1493-1513, (2010); Bedsworth L. W., Taylor M. R., Learning from California’s zero-emission vehicle program, California Economic Policy, 3, 4, (2007); Bettencourt L. M., Kaur J., Evolution and structure of sustainability science, Proceedings of the National Academy of Sciences, 108, 49, pp. 19540-19545, (2011); Broadus R. N., Toward a definition of “bibliometrics”, Scientometrics, 12, 5, pp. 373-379, (1987); Das S., Kong X., Wei Z., Liu J., Scientometric and Bibliographic Analysis of Pedestrian Safety Research, Transportation Research Record, (2023); Dymen C., Henriksson A., Spatial planning and its contribution to climate friendly and sustainable transport solutions, (2009); Eyuboglu M., (2023); Hart M., The guide to sustainable community indicators (2. Baskı), (1999); Hosseini S. E., Wahid M. A., Hydrogen production from renewable and sustainable energy resources: Promising green energy carrier for clean development, Renewable and Sustainable Energy Reviews, 57, pp. 850-866, (2016); Kabakus A. K., Ozkose H., Ahmet A. Y. A. Z., Society 5.0 Research: Performance Analysis and Science Mapping, Gümüşhane Üniversitesi Sosyal Bilimler Dergisi, 14, 1, pp. 311-328, (2023); Leipzig I. T. F., Reducing transport greenhouse gas emissions: trends & data, Background for the 2010 International Transport Forum, (2010); Nicolaisen J., Bibliometrics and citation analysis: From the science citation index to cybermetrics, (2010); Nikolaidis P., Poullikkas A., A comparative overview of hydrogen production processes, Renewable and sustainable energy reviews, 67, pp. 597-611, (2017); Shah K. J., Pan S. Y., Lee I., Kim H., You Z., Zheng J. M., Chiang P. C., Green transportation for sustainability: Review of current barriers, strategies, and innovative technologies, Journal of Cleaner Production, 326, (2021); Van Leeuwen T., The application of bibliometric analyses in the evaluation of social science research. Who benefits from it, and why it is still feasible, Scientometrics, 66, 1, pp. 133-154, (2006)","N. Kabakuş; Ataturk University, Faculty of Applied Sciences, Department of Emergency and Disaster Management, Erzurum, 25240, Turkey; email: nsirin@atauni.edu.tr","","Gumushane University","","","","","","2146538X","","","","English","Gumushane Univ. J. Sci.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-105004059451" -"Khorshidi M.S.; Merigó J.M.; Beydoun G.","Khorshidi, Mohammad Sadegh (57189616748); Merigó, José M. (23482135100); Beydoun, Ghassan (55912707700)","57189616748; 23482135100; 55912707700","Half a Century of Information Processing & Management: A bibliometric retrospective","2025","Information Processing and Management","62","6","104238","","","","0","10.1016/j.ipm.2025.104238","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105007143996&doi=10.1016%2fj.ipm.2025.104238&partnerID=40&md5=8834a7e285c415eb22d714c69252e786","School of Computer Science, Faculty of Engineering and Information Technology, University of Technology Sydney, 81 Broadway, Ultimo, 2007, NSW, Australia","Khorshidi M.S., School of Computer Science, Faculty of Engineering and Information Technology, University of Technology Sydney, 81 Broadway, Ultimo, 2007, NSW, Australia; Merigó J.M., School of Computer Science, Faculty of Engineering and Information Technology, University of Technology Sydney, 81 Broadway, Ultimo, 2007, NSW, Australia; Beydoun G., School of Computer Science, Faculty of Engineering and Information Technology, University of Technology Sydney, 81 Broadway, Ultimo, 2007, NSW, Australia","Established in 1963 under the title Information Storage and Retrieval, the journal adopted its current name, Information Processing & Management (IPM), in 1975, reflecting a broadening scope aligned with computational and cognitive developments in information science. This study uses data from Web of Science and Scopus databases to deliver a longitudinal, multi-perspective bibliometric and science mapping analysis of IPM's evolution from 1963 to 2023. Employing co-citation analysis, bibliographic coupling, keyword co-occurrence, and thematic mapping via VOSviewer and Bibliometrix, the analysis delineates the structural, conceptual, and topical transformation of the journal content. Co-citation networks uncover foundational cores in information retrieval, relevance theory, and evaluation methodologies, while also revealing temporal shifts toward natural language processing, deep learning, and social media analytics. Bibliographic coupling identifies coherent intellectual clusters centered on GNN-based recommendation systems, blockchain-secured infrastructures, and sentiment-aware retrieval frameworks. Keyword co-occurrence and topic evolution trajectories illustrate the journal's recent pivot toward transformer models, misinformation detection, ethical AI, and interdisciplinary convergence across cognitive science, machine learning, and computational linguistics. Regional co-word analysis underscores epistemological diversity and geographic differentiation across North America, Europe, and East Asia. Productivity and influence metrics highlight the ascent of East Asian institutions and the emergence of globally distributed citation impact. Finally, SciVal-based topic and topic cluster analyses reveal the journal's role in advancing highly cited research (as measured by FWCI) in areas such as ABSA, multi-view clustering, and health informatics. This work not only charts IPM's conceptual landscape and disciplinary diffusion but also provides actionable intelligence on the journal's strategic positioning within the broader information and computational sciences. © 2025 The Author(s)","Bibliometrics; Information Processing; Management; Scopus; VOS viewer; Web of Science","Bibliographic retrieval systems; Data mining; Data reduction; Enterprise resource management; Finance; Linguistics; Marketing; Metadata; Online searching; Recommender systems; Vocabulary control; 'current; Bibliographic couplings; Bibliometric; Co-occurrence; Cognitive development; Computational development; Information storage and retrieval; Scopus; VOS viewer; Web of Science; Information management","","","","","","","Aizawa A., An information-theoretic perspective of tf–idf measures, Information Processing & Management, 39, 1, pp. 45-65, (2003); An P., Wang Z.Y., Zhang C.J., Ensemble unsupervised autoencoders and Gaussian mixture model for cyberattack detection, Information Processing & Management, 59, 2, (2022); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Baeza-Yates R., Ribeiro-Neto B., Modern information retrieval: The concepts and technology behind search, (1999); Bates M.J., Where should the person stop and the information search interface start?, Information Processing & Management, 26, 5, pp. 575-591, (1990); Berdik D., Otoum S., Schmidt N., Porter D., Jararweh Y., A survey on blockchain for information systems management and security, Information Processing & Management, 58, 1, (2021); Bergstrom C.T., West J.D., Wiseman M.A., The Eigenfactor Metrics, Journal of Neuroscience, 28, 45, pp. 11433-11434, (2008); Blei D.M., Ng A.Y., Jordan M.I., Latent Dirichlet Allocation, Journal of Machine Learning Research, 3, pp. 993-1022, (2003); Bystrom K., Jarvelin K., Task complexity affects information-seeking and use, Information Processing & Management, 31, 2, pp. 191-213, (1995); Callon M., Courtial J.P., Turner W.A., Bauin S., From translations to problematic networks: An introduction to co-word analysis, Social Science Information, 22, 2, pp. 191-235, (1983); Chen X., Vorvoreanu M., Madhavan K., Mining enterprise social media data: Identifying perception differences between data scientists and the general public, Information Processing & Management, 57, 3, (2020); (2025); Deerwester S., Dumais S.T., Furnas G.W., Landauer T.K., Harshman R., Indexing by latent semantic analysis, Journal of the American Society for Information Science, 41, 6, pp. 391-407, (1990); Devlin J., Chang M.W., Lee K., Toutanova K., BERT: Pre-training of deep bidirectional transformers for language understanding, Proceedings of the 2019 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies (NAACL-HLT), 1, pp. 4171-4186, (2019); Devlin J., Chang M.-W., Lee K., Toutanova K., BERT: Pre-training of deep bidirectional transformers for language understanding, Proceedings of NAACL-HLT 2019, pp. 4171-4186, (2019); Ding Y., Chowdhury G.G., Foo S., Bibliometric cartography of information retrieval research by using co-word analysis, Information Processing & Management, 37, 6, pp. 817-842, (2001); Ding Y., Rousseau R., Wolfram D., Measuring scholarly impact: Methods and practice, (2014); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); (2024); Figuerola-Wischke A., Merigo J.M., Gil-Lafuente A.M., Kydland F.E., Amiguet L., The Scandinavian Journal of Economics at 125: a bibliometric overview, Scandinavian Journal of Economics, 126, pp. 643-697, (2024); Fornell C., A comparative analysis of two structural equation models: LISREL and PLS applied to market data, Advances in Consumer Research, Advances in Consumer Research, 8, pp. 443-447, (1981); Garfield E., Citation indexes for science: New dimension in documentation through association of ideas, Science, 122, 3159, pp. 108-111, (1955); Guan L., Laporte G., Merigo J.M., Nickel S., Rahimi I., Saldanha-da-Gama F., 50 years of Computers & Operations Research: A bibliometric analysis, Computers & Operations Research, 175, (2025); 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Merigó; School of Computer Science, Faculty of Engineering and Information Technology, University of Technology Sydney, Ultimo, 81 Broadway, 2007, Australia; email: Jose.Merigo@uts.edu.au","","Elsevier Ltd","","","","","","03064573","","IPMAD","","English","Inf. Process. Manage.","Article","Final","All Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-105007143996" -"Adedayo H.B.; Albarody T.M.; Sopian K.; Muhsan A.S.; Adedayo-Ojo A.A.; Alawi N.M.","Adedayo, Habeeb Bolaji (57222082020); Albarody, Thar Mohammed (37114302300); Sopian, Kamaruzzaman (7003375391); Muhsan, Ali Samer (54585662300); Adedayo-Ojo, Aishat Adebonike (59774659500); Alawi, Nabil Majd (56119502600)","57222082020; 37114302300; 7003375391; 54585662300; 59774659500; 56119502600","Plasma-based technologies for sustainable hydrogen production: A data-driven bibliometric","2025","Materials Research Proceedings","53","","","17","42","25","0","10.21741/9781644903575-2","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105005284081&doi=10.21741%2f9781644903575-2&partnerID=40&md5=51986af0d670842c3667a8aa8bcf7872","Department of Mechanical Engineering, Universiti Teknologi Petronas, Perak, Seri Iskander, 32610, Malaysia; Department of Management and Humanities, Universiti Teknologi Petronas, Perak, Seri Iskander, 32610, Malaysia; Chemical Engineering Department, University of Technology-Iraq, Baghdad, Iraq","Adedayo H.B., Department of Mechanical Engineering, Universiti Teknologi Petronas, Perak, Seri Iskander, 32610, Malaysia; Albarody T.M., Department of Mechanical Engineering, Universiti Teknologi Petronas, Perak, Seri Iskander, 32610, Malaysia; Sopian K., Department of Mechanical Engineering, Universiti Teknologi Petronas, Perak, Seri Iskander, 32610, Malaysia; Muhsan A.S., Department of Mechanical Engineering, Universiti Teknologi Petronas, Perak, Seri Iskander, 32610, Malaysia; Adedayo-Ojo A.A., Department of Management and Humanities, Universiti Teknologi Petronas, Perak, Seri Iskander, 32610, Malaysia; Alawi N.M., Chemical Engineering Department, University of Technology-Iraq, Baghdad, Iraq","The quest for sustainable hydrogen production has intensified in the past decade, driven by the global energy transition from fossil fuels to hydrogen-based alternatives. This urgency necessitates the exploration of innovative technologies beyond traditional methods. Therefore, this study pioneers a bibliometric analysis to evaluate the potential of plasma-based technologies for sustainable hydrogen production. Methodologically, the systematic data adheres strictly to the PRISMA 2020 framework. The Shiny App of the Bibliometrix R package is used to uncover the performance analysis and science mapping visualization of the bibliometric dataset. The findings revealed 581 published documents following database merging, with 152 records excluded by automated tools and another 152 through screening with PRISMA. This study is of great interest to academic and industrial relevance, as evidenced by 277 documents with annual growth rate (22.57%), authors’ contributions (n = 1,185), co-authorship (30.32%), and average citation rate (n = 23). Notably, microwave plasma emerges as the most dominant technology for hydrogen production from natural gas reforming, achieving a 65% volumetric yield among non-thermal plasma variants, alongside warm plasma (48%) and thermal plasma (67%). Collaborative efforts between China and Australia in energy policy research emphasize the importance of international partnerships in advancing sustainable energy solutions. The emerging research trends in plasma gasification, water splitting, and hydrogen evolution reactions, signal a paradigm shift towards more sustainable, efficient hydrogen production techniques. Ongoing research is poised to enhance efficiency and environmental sustainability, contributing vitally to a net-zero emission future. © 2025 by the author(s).","Bibliometric Analysis; Hydrogen Production; Merged Dataset; Plasma Technologies; Sustainable Energy","","","","","","Petroleum Technology Development Fund, PTDF, (PTDF/ED/OSS/PHD/HBA/1738/2020PHD046); Petroleum Technology Development Fund, PTDF","The authors sincerely appreciate the financial assistance received from the Petroleum Technology Development Fund (PTDF), Nigeria. Towards an effective approach to industrial waste flare utilization in producing high-value products for sustainable energy generation. Under the sponsorship candidate number: PTDF/ED/OSS/PHD/HBA/1738/2020PHD046. Also, the prestigious citadel of learning \u2013 Universiti Teknologi PETRONAS is acknowledged.","Hassan Q., Algburi S., Sameen A. Z., Salman H. M., Jaszczur M., Green hydrogen: A pathway to a sustainable energy future, Int. J. 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K., Magid A., Microwave plasma gasification for enhanced oil recovery and sustainable waste management, ASME 2016 10th International Conference on Energy Sustainability, ES 2016, collocated with the ASME 2016 Power Conference and the ASME 2016 14th International Conference on Fuel Cell Science, Engineering and Technology, pp. 1-13, (2016); Akay G., Sustainable ammonia and advanced symbiotic fertilizer production using catalytic multi-reaction-zone reactors with nonthermal plasma and simultaneous reactive separation, ACS Sustain. Chem. Eng, 5, 12, pp. 11588-11606, (2017); Peng R., Chen P., Schiappacasse P., Zhou C., Anderson N., Chen E., Liu D., Cheng J., Hatzenbeller Y., Addy R., Zhang M., Liu Y., Ruan Y., A review on the non-thermal plasma-assisted ammonia synthesis technologies, J. Clean. Prod, 177, pp. 597-609, (2018); George A., Et al., A Review of Non-Thermal Plasma Technology: A novel solution for CO2 conversion and utilization, Renew. Sustain. Energy Rev, 135, (2021); Tabu B., Et al., Hydrogen from cellulose and low-density polyethylene via atmospheric pressure nonthermal plasma, Int. J. Hydrogen Energy, 49, pp. 745-763, (2024); Tabu B., Et al., Nonthermal atmospheric plasma reactors for hydrogen production from low-density polyethylene, Int. J. Hydrogen Energy, 47, 94, pp. 39743-39757, (2022); Boscherini M., Storione A., Minelli M., Miccio F., Doghieri F., New Perspectives on Catalytic Hydrogen Production by the Reforming, Partial Oxidation and Decomposition of Methane and Biogas, Energies, 16, 17, (2023); Gonzalez-Casamachin D. A., Qin T., Huang W. M., Rangarajan S., Zhang L., Baltrusaitis J., Actively Learned Optimal Sustainable Operation of Plasma-Catalyzed Methane Bireforming on La0. 7Ce0. 3NiO3 Perovskite, ACS Sustain. Chem. Eng, 12, 1, pp. 610-622, (2023); Nguyen H. M., Omidkar A., Li W., Meng S., Li Z., Song H., Non-thermal plasma assisted catalytic nitrogen fixation with methane at ambient conditions, Chem. Eng. 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S., Will China achieve its 2060 carbon neutral commitment from the provincial perspective?, Adv. Clim. Chang. Res, 13, 2, pp. 169-178, (2022); Li J., Ho M. S., Xie C., Stern N., China’s flexibility challenge in achieving carbon neutrality by 2060, Renew. Sustain. Energy Rev, 158, (2022); Italy ’ s National Energy Strategy: For a more competitive and sustainable energy, (2013); Bollino C. A., The role of the National Energy Strategy in boosting italian economy, Econ. Policy Energy Environ, 2, 2013, pp. 19-35, (2013); Haq B., Salahu Muhammed N., Liu J., Tong Chua H., Enhanced natural gas production using CO2 injection: Application to sustainable hydrogen production, Fuel, 347, (2023); Tamala J. K., Maramag E. I., Simeon K. A., Ignacio J. J., A bibliometric analysis of sustainable oil and gas production research using VOSviewer, Clean. Eng. Technol, 7, (2022); Hua Y., Oliphant M., Hu E. J., Development of renewable energy in Australia and China: A comparison of policies and status, Renew. Energy, 85, pp. 1044-1051, (2016); Young M. A., Clough G., Net Zero Emissions and Free Trade Agreements: Efforts At Integrating Climate Goals By the United Kingdom and Australia, 72, 2, (2023); Senior B., Et al., Carbon capture and storage in China – Main findings from China- UK Near Zero Emissions Coal (NZEC) initiative, Energy Procedia, 4, pp. 5956-5965, (2011); Jing D., Et al., Efficient solar hydrogen production by photocatalytic water splitting: From fundamental study to pilot demonstration, Int. J. Hydrogen Energy, 35, 13, pp. 7087-7097, (2010); Yuan L., Han C., Yang M. Q., Xu Y. J., Photocatalytic water splitting for solar hydrogen generation: fundamentals and recent advancements, Int. Rev. Phys. Chem, 35, 1, pp. 1-36, (2016)","H.B. Adedayo; Department of Mechanical Engineering, Universiti Teknologi Petronas, Seri Iskander, Perak, 32610, Malaysia; email: habeeb_21002757@utp.edu.my; T.M. Albarody; Department of Mechanical Engineering, Universiti Teknologi Petronas, Seri Iskander, Perak, 32610, Malaysia; email: dher.albarody@utp.edu.my","Sapiaa N.A.H.; Jumbri K.; Kee L.M.; Ayodele B.V.; Ahmad S.I.","Association of American Publishers","","International Conference on Decarbonization Technology, ICDT 2024","10 September 2024 through 11 September 2024","Sabah","331549","24743941","978-164490356-8","","","English","Mater. Res. Proc.","Conference paper","Final","","Scopus","2-s2.0-105005284081" -"Srivastava P.; Bano S.","Srivastava, Prakhar (59561241100); Bano, Samina (57188714049)","59561241100; 57188714049","Mapping the landscape of cross-group friendship research: a bibliometric review","2025","Current Psychology","44","5","","4055","4071","16","0","10.1007/s12144-025-07466-y","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105003742455&doi=10.1007%2fs12144-025-07466-y&partnerID=40&md5=6892bca6bd04cee6bcfab912ff834810","Department of Psychology, Jamia Millia Islamia, New Delhi, 110025, India","Srivastava P., Department of Psychology, Jamia Millia Islamia, New Delhi, 110025, India; Bano S., Department of Psychology, Jamia Millia Islamia, New Delhi, 110025, India","Cross-group friendships play a crucial role in reducing prejudice and promoting social inclusion. While previous reviews have advanced our understanding using narrative or meta-analytic methods, they may not capture the full breadth of the research landscape. To address this limitation and provide a comprehensive mapping of the field, our review employs bibliometric analysis. We examined 323 scholarly works from the Scopus database (1961–2023) using Vosviewer and R-bibliometrix. Through performance analysis and science mapping, our study reveals the field’s evolution, identifying key contributors, leading institutions, and influential journals. Co-citation analysis uncovers three main thematic clusters: the Contact Hypothesis, Dynamics and Impact of Cross-Group Friendships, and Direct and Extended Cross-Group Friendships. Additionally, bibliographic coupling analysis identifies emerging themes, including interethnic friendships among children, cross-group friendships as catalysts for societal change, and advances in intergroup contact theory. This comprehensive mapping complements existing reviews by offering a broader perspective on the field’s structure and evolution. The insights gained from this review could potentially guide future research directions and inform policy and intervention strategies aimed at mitigating prejudice and promoting social cohesion. We acknowledge limitations related to database and language inclusion, and encourage further exploration. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025.","Bibliometric analysis; Contact theory; Cross-group friendship; Intergroup contact","","","","","","","","Allport G.W., The nature of prejudice, (1954); IMPACT IN ACTION: Reflecting on APA’s Strategic Plan and Progress To-Date, (2023); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bagci S.C., Celebi E., Cross-group friendships and outgroup attitudes among turkish-kurdish ethnic groups: Does perceived interethnic conflict moderate the friendship-attitude link?>, Journal of Applied Social Psychology, 47, 2, pp. 59-73, (2016); Bagci S.C., Celebi E., Are your cross-ethnic friends ethnic and/or national group identifiers? 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Vezzali L., Brambilla M., Giovannini D., Paolo Colucci F., Strengthening purity: Moral Purity as a mediator of direct and extended cross-group friendships on sexual prejudice, Journal of Homosexuality, 64, 6, pp. 716-730, (2016); Vezzali L., Hewstone M., Capozza D., Trifiletti E., Bernardo G.A.D., Improving Intergroup relations with extended contact among Young children: Mediation by Intergroup Empathy and Moderation by Direct Intergroup Contact, Journal of Community & Applied Social Psychology, 27, 1, pp. 35-49, (2016); Vezzali L., Birtel M.D., Di Bernardo G.A., Stathi S., Crisp R.J., Cadamuro A., Visintin E.P., Don’t hurt my outgroup friend: A multifaceted form of imagined contact promotes intentions to counteract bullying, Group Processes & Intergroup Relations, 23, 5, pp. 643-663, (2019); Voci A., Hewstone M., Swart H., Veneziani C.A., Refining the association between intergroup contact and intergroup forgiveness in Northern Ireland: Type of contact, prior conflict experience, and group identification, Group Processes & Intergroup Relations, 18, 5, pp. 589-608, (2015); Wright S.C., Aron A., McLaughlin-Volpe T., Ropp S.A., The extended contact effect: Knowledge of cross-group friendships and prejudice, Journal of Personality and Social Psychology, 73, 1, pp. 73-90, (1997); Zhou S., Page-Gould E., Aron A., Moyer A., Hewstone M., The extended contact hypothesis: A Meta-analysis on 20 years of Research, Personality and Social Psychology Review, 23, 2, pp. 132-160, (2018); Zupic I., Cater T., Bibliometric methods in management and Organization, Organizational Research Methods, 18, 3, pp. 429-472, (2014)","P. Srivastava; Department of Psychology, Jamia Millia Islamia, New Delhi, 110025, India; email: prakhar.vastav13@gmail.com","","Springer","","","","","","10461310","","","","English","Curr. Psychol.","Article","Final","","Scopus","2-s2.0-105003742455" -"Srivastava R.; Sharma M.","Srivastava, Rajeev (57221637321); Sharma, Meenakshi (59936869200)","57221637321; 59936869200","Intellectual research landscape of neuromarketing: bibliometric network analysis (2004–2021)","2024","International Journal of Electronic Business","19","2","","209","234","25","1","10.1504/IJEB.2024.137700","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189697542&doi=10.1504%2fIJEB.2024.137700&partnerID=40&md5=6be8c2eb804bc2a92e76ec0ac823d2ff","IMS Unison University, Makkawala Greens Mussoorie, Diversion Road, Uttarakhand, Dehradun, 248009, India; University of Petroleum and Energy Studies, Dehradun, India","Srivastava R., IMS Unison University, Makkawala Greens Mussoorie, Diversion Road, Uttarakhand, Dehradun, 248009, India; Sharma M., University of Petroleum and Energy Studies, Dehradun, India","Neuromarketing is an evolving field that integrates psychology, neuroscience, and marketing. Zavadskas et al. (2019) state, to improve the performance of one-to-one marketing, it is imperative to analyse prospective buyers’ emotional and behavioural states, valence and arousal. With this aim, the current study uses comprehensive bibliometric analysis to assess the research landscape of the neuromarketing field. A total of 694 documents were obtained from the Web of Science, published in the neuromarketing field during the last 18 years. Further, the science mapping analysis was performed to identify relevant networks and thematic clusters. The study’s findings will be a useful resource for scholars, assist them in understanding the publication trend, top articles attributed in terms of journals, scholars, citations, and impact factors and also build a scope for future research in the field of neuromarketing. Marketers and practitioners of the digital age will be able to develop effective neuromarketing strategies for a sustainable business. Copyright © 2024 Inderscience Enterprises Ltd.","bibliometric analysis; bibliometrix; biblioshiny; neuromarketing; neuroscience performance analysis; science mapping","Commerce; Marketing; Neurology; Bibliometric; Bibliometrics analysis; Bibliometrix; Biblioshiny; Neuromarketing; Neuroscience performance analyse; One-to-one marketing; Performance; Performances analysis; Science mapping; Mapping","","","","","","","Abayi M., Khoshtinat B., Study of the impact of advertising on online shopping tendency for airline tickets by considering motivational factors and emotional factors, Procedia Economics and Finance, 36, 16, pp. 532-539, (2016); Adelsarbanlar N., Khoshtinat B., Critical factors and advantage factors influencing the implementation of viral marketing by considering the mediating role of Islamic marketing. 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Srivastava; IMS Unison University, Dehradun, Makkawala Greens Mussoorie, Diversion Road, Uttarakhand, 248009, India; email: dr.rajeev.mnnit@gmail.com","","Inderscience Publishers","","","","","","14706067","","","","English","Int. J. Electron. Bus.","Article","Final","","Scopus","2-s2.0-85189697542" -"Gupta N.; Agarwal A.K.; Tiwari M.K.","Gupta, Neema (58938429600); Agarwal, Ambuj Kumar (57189048540); Tiwari, Muklesh Kumar (57930455600)","58938429600; 57189048540; 57930455600","A bibliometric analysis of three decades of research on gig workers","2025","Organizational Sociology in the Digital Age","","","","283","318","35","0","10.4018/979-8-3693-7398-9.ch015","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105005136963&doi=10.4018%2f979-8-3693-7398-9.ch015&partnerID=40&md5=14e57a8de71c1597126bf2982d7a37d9","Chandigarh University, Mohali, India; Sharda University, Greater Noida, India","Gupta N., Chandigarh University, Mohali, India; Agarwal A.K., Sharda University, Greater Noida, India; Tiwari M.K., Chandigarh University, Mohali, India","The chapter addresses a gap in global knowledge on gig workers through a comprehensive bibliometric overview using Bibliometrix and Biblioshiny. Analyzing 1,430 articles from the Scopus database (1987- 2024), a performance analysis and science mapping are used. Covering 887 sources from 65 countries and 2,981 authors, the study identifies three main clusters: Employment, Workers, and Human. The research examines scientific productivity, prolific authors, citable documents, relevant institutions, cited countries, keyword co-occurrence, thematic mapping, co-citations, and country collaborations. Findings reveal a significant rise in publications over the past decade with most authors contributing at least one article. The USA, UK, China, Germany, Australia, and India are the top productive countries, highlighting notable international collaborations. Key journals include 'New Technology, Work and Employment' and 'Work, Employment and Society'. This research enhances understanding of gig workers' literature and offers insights into the field's implications and future directions. © 2025 by IGI Global Scientific Publishing.","","Australia; Bibliometric; Bibliometrics analysis; Co-occurrence; Cocitation; Global knowledge; Performances analysis; Scopus database; Thematic mapping; Workers'","","","","","","","Aayog N.I.T.I., India, (2022); Abbas A.F., Jusoh A., Mas'od A., Alharthi R.H., A Bibliometric Analysis of Publications on Social Media Influencers Using Vosviewer, (2021); Aboobaker N., Edward M., Zakkariya K.A., Workplace spirituality, well-being at work and employee loyalty in a gig economy: Multi-group analysis across temporary vs permanent employment status, Personnel Review, 51, 9, pp. 2162-2180, (2021); Akter S., Uddin H., Tajuddin A.H., Knowledge mapping of microfinance performance research: A bibliometric analysis, International Journal of Social Economics, 48, 3, pp. 399-418, (2021); Andrew A., Cattan S., Dias M.C., Farquharson C., Kraftman L., Krutikova S., Phimister A., Sevilla A., How are mothers and fathers balancing work and family under lockdown?, (2020); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bajwa U., Gastaldo D., Di Ruggiero E., Knorr L., The health of workers in the global gig economy, Globalization and Health, 14, 1, (2018); Bajwa U., Knorr L., Di Ruggiero E., Gastaldo D., Zendel A., Towards an understanding of workers' experiences in the global gig economy, Globalization and Health, 14, 124, pp. 2-4, (2018); Barzilay A.R., Discrimination without discriminating? 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Human Resource Management Review, 25, 2, pp. 188-204, (2015); Wiessner D., US judge says Uber drivers are not company's employees, (2018); Wolfe M.T., Patel P.C., Exploring the differences in perceptions of work importance and job usefulness to society between self-employed and employed individuals, Journal of Business Venturing Insights, 12, (2019); Wood A.J., Graham M., Lehdonvirta V., Hjorth I., Good gig, Bad gig: Autonomy and algorithmic control in the global gig economy, Work, Employment and Society, 33, 1, pp. 56-75, (2018); Yaraghi N., Ravi S., The current and future state of the sharing economy, (2017); Zamil I.A., Ramakrishnan S., Jamal N.M., Hatif M.A., Khatib S.F.A., Drivers of corporate voluntary disclosure: A systematic review, Journal of Financial Reporting & Accounting (Online), 21, 2, pp. 232-267, (2021); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2014)","","","IGI Global","","","","","","","979-836937400-9; 979-836937398-9","","","English","Organ. sociol. in the digit. age","Book chapter","Final","","Scopus","2-s2.0-105005136963" -"Zhong S.; Yin X.; Li X.; Feng C.; Gao Z.; Liao X.; Yang S.; He S.","Zhong, Sen (57605424600); Yin, Xiaobing (58864973500); Li, Xiaolan (59320384400); Feng, Chaobo (57203243497); Gao, Zhiqiang (59321392300); Liao, Xiang (55244392300); Yang, Sheng (57226387490); He, Shisheng (12042341600)","57605424600; 58864973500; 59320384400; 57203243497; 59321392300; 55244392300; 57226387490; 12042341600","Artificial intelligence applications in bone fractures: A bibliometric and science mapping analysis","2024","Digital Health","10","","","","","","2","10.1177/20552076241279238","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85203515209&doi=10.1177%2f20552076241279238&partnerID=40&md5=9c0e48f9dbddec088963f448d96cb255","Department of Orthopedic, Spinal Pain Research Institute, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China; Nursing Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China; Fuzhou Medical College of Nanchang University, School of Stomatology, Fuzhou, China; National Key Clinical Pain Medicine of China, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China; Department of Joint Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China","Zhong S., Department of Orthopedic, Spinal Pain Research Institute, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China; Yin X., Nursing Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China; Li X., Fuzhou Medical College of Nanchang University, School of Stomatology, Fuzhou, China; Feng C., National Key Clinical Pain Medicine of China, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China; Gao Z., Department of Joint Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; Liao X., National Key Clinical Pain Medicine of China, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China; Yang S., Department of Orthopedic, Spinal Pain Research Institute, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China; He S., Department of Orthopedic, Spinal Pain Research Institute, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China","Background: Bone fractures are a common medical issue worldwide, causing a serious economic burden on society. In recent years, the application of artificial intelligence (AI) in the field of fracture has developed rapidly, especially in fracture diagnosis, where AI has shown significant capabilities comparable to those of professional orthopedic surgeons. This study aimed to review the development process and applications of AI in the field of fracture using bibliometric analysis, while analyzing the research hotspots and future trends in the field. Materials and methods: Studies on AI and fracture were retrieved from the Web of Science Core Collections since 1990, a retrospective bibliometric and visualized study of the filtered data was conducted through CiteSpace and Bibliometrix R package. Results: A total of 1063 publications were included in the analysis, with the annual publication rapidly growing since 2017. China had the most publications, and the United States had the most citations. Technical University of Munich, Germany, had the most publications. Doornberg JN was the most productive author. Most research in this field was published in Scientific Reports. Doi K's 2007 review in Computerized Medical Imaging and Graphics was the most influential paper. Conclusion: AI application in fracture has achieved outstanding results and will continue to progress. In this study, we used a bibliometric analysis to assist researchers in understanding the basic knowledge structure, research hotspots, and future trends in this field, to further promote the development of AI applications in fracture. © The Author(s) 2024.","Artificial intelligence; bibliometric; bibliometrix; bone fracture; CiteSpace; research trends","","","","","","Bullet Edits Limited; Nanshan District Health Science and Technology Project, (NS2023002); Yunnan Academician Expert Workstation, (202205AF150058); National Natural Science Foundation of China, NSFC, (82372442); National Key Research and Development Program of China, NKRDPC, (2022YFC3602203); Science and Technology Commission of Shanghai Municipality, STCSM, (23015820300)","Funding text 1: We thank Bullet Edits Limited for the linguistic editing and proofreading of the manuscript. The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was funded by the National Natural Science Foundation of China (Grant No. 82372442), the Science and Technology Commission of Shanghai Municipality (Grant No. 23015820300), Yunnan Academician Expert Workstation (Grant No. 202205AF150058), the National Key Research and Development Program of China (Grant No. 2022YFC3602203), and the Nanshan District Health Science and Technology Project (Grant No. NS2023002).; Funding text 2: The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was funded by the National Natural Science Foundation of China (Grant No. 82372442), the Science and Technology Commission of Shanghai Municipality (Grant No. 23015820300), Yunnan Academician Expert Workstation (Grant No. 202205AF150058), the National Key Research and Development Program of China (Grant No. 2022YFC3602203), and the Nanshan District Health Science and Technology Project (Grant No. NS2023002). ","Wu A.M., Bisignano C., James S.L., Et al., Global, regional, and national burden of bone fractures in 204 countries and territories, 1990–2019: A systematic analysis from the global burden of disease study 2019, Lancet Healthy Longev, 2, (2021); Borgstrom F., Karlsson L., Ortsater G., Et al., Fragility fractures in Europe: Burden, management and opportunities, Arch Osteoporos, 15, (2020); Lindsey R., Daluiski A., Chopra S., Et al., Deep neural network improves fracture detection by clinicians, Proc Natl Acad Sci USA, 115, pp. 11591-11596, (2018); Hallas P., Ellingsen T., Errors in fracture diagnoses in the emergency department–characteristics of patients and diurnal variation, BMC Emerg Med, 6, (2006); Wei C.J., Tsai W.C., Tiu C.M., Et al., Systematic analysis of missed extremity fractures in emergency radiology, Acta Radiol, 47, pp. 710-717, (2006); He K.M., Zhang X.Y., Ren S.Q., Et al., pp. 1026-1034; Olczak J., Fahlberg N., Maki A., Et al., Artificial intelligence for analyzing orthopedic trauma radiographs deep learning algorithms-are they on par with humans for diagnosing fractures?, Acta Orthop, 88, pp. 581-586, (2017); Zhao H., You J.M., Peng Y.X., Et al., Machine learning algorithm using electronic chart-derived data to predict delirium after elderly hip fracture surgeries: A retrospective case-control study, Front Surg, 8, (2021); He Y., Wang J., Zhang J., Et al., Erratum to: A prospective study on predicting local recurrence of giant cell tumour of bone by evaluating preoperative imaging features of the tumour around the knee joint, Radiol Med, 122, (2017); Lambrechts A., Wirix-Speetjens R., Maes F., Et al., Artificial intelligence based patient-specific preoperative planning algorithm for total knee arthroplasty, Front Robot AI, 9, (2022); Eskinazi I., Fregly B.J., Surrogate modeling of deformable joint contact using artificial neural networks, Med Eng Phys, 37, pp. 885-891, (2015); Chen C., Hu Z., Liu S., Et al., Emerging trends in regenerative medicine: A scientometric analysis in CiteSpace, Expert Opin Biol Ther, 12, pp. 593-608, (2012); Fortunato S., Bergstrom C.T., Borner K., Et al., Science of science, Science, 359, (2018); Chen C., An information-theoretic view of visual analytics, IEEE Comput Graph Appl, 28, pp. 18-23, (2008); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J Informetr, 11, pp. 959-975, (2017); Gan K.F., Xu D.L., Lin Y.M., Et al., Artificial intelligence detection of distal radius fractures: A comparison between the convolutional neural network and professional assessments, Acta Orthop, 90, pp. 394-400, (2019); Jin L., Yang J.C., Kuang K.M., Et al., Deep-learning-assisted detection and segmentation of rib fractures from CT scans: Development and validation of FracNet, EBioMedicine, 62, (2020); Zhou Q.Q., Wang J.S., Tang W., Et al., Automatic detection and classification of rib fractures on thoracic CT using convolutional neural network: Accuracy and feasibility, Korean J Radiol, 21, pp. 869-879, (2020); Doi K., Computer-aided diagnosis in medical imaging: Historical review, current status and future potential, Comput Med Imaging Graph, 31, pp. 198-211, (2007); Gyftopoulos S., Lin D.N., Knoll F., Et al., Artificial intelligence in musculoskeletal imaging: Current status and future directions, Am J Roentgenol, 213, pp. 506-513, (2019); Langerhuizen D.W.G., Janssen S.J., Mallee W.H., Et al., What are the applications and limitations of artificial intelligence for fracture detection and classification in orthopaedic trauma imaging? A systematic review, Clin Orthop Relat Res, 477, pp. 2482-2491, (2019); Tomita N., Cheung Y.Y., Hassanpour S., Deep neural networks for automatic detection of osteoporotic vertebral fractures on CT scans, Comput Biol Med, 98, pp. 8-15, (2018); Burns J.E., Yao J.H., Summers R.M., Vertebral body compression fractures and bone density: Automated detection and classification on CT images, Radiology, 284, pp. 788-797, (2017); De Brijun B., Cranney A., O'Donnell S., Et al., Identifying wrist fracture patients with high accuracy by automatic categorization of x-ray reports, J Am Med Inf Assoc, 13, pp. 696-698, (2006); Kasai S., Li F., Shiraishi J., Et al., Computerized detection of vertebral compression fractures on lateral chest radiographs: Preliminary results with a tool for early detection of osteoporosis, Med Phys, 33, pp. 4664-4674, (2006); Missoum S., Jiang P., Hu C.C., Et al., Towards hip fracture prediction using finite element analysis and machine learning, J Bone Miner Res, 28, (2013); Nishiyama K.K., Ito M., Harada A., Et al., Classification of women with and without hip fracture based on quantitative computed tomography and finite element analysis, Osteoporos Int, 25, pp. 619-626, (2014); Kim D.H., MacKinnon T., Artificial intelligence in fracture detection: Transfer learning from deep convolutional neural networks, Clin Radiol, 73, pp. 439-445, (2018); Hardalac F., Uysal F., Peker O., Et al., Fracture detection in wrist X-ray images using deep learning-based object detection models, Sensors (Basel), 22, (2022); Pranata Y.D., Wang K.C., Wang J.C., Et al., Deep learning and SURF for automated classification and detection of calcaneus fractures in CT images, Comput Methods Programs Biomed, 171, pp. 27-37, (2019); Uysal F., Hardalac F., Peker O., Et al., Classification of shoulder X-ray images with deep learning ensemble models, Appl Sci-Basel, 11, (2021); Polzer C., Yilmaz E., Meyer C., Et al., AI-based automated detection and stability analysis of traumatic vertebral body fractures on computed tomography, Eur J Radiol, 173, (2024); Starosolski Z.A., Kan J.H., Annapragada A.; Iyer S., Sowniya A., Blair A., Et al., pp. 726-730; Wigderowitz C.A., Paterson C.R., Dashti H., Et al., Prediction of bone strength from cancellous structure of the distal radius: Can we improve on DXA?, Osteoporos Int, 11, pp. 840-846, (2000); Mohamed E.I., Maiolo C., Linder R., Et al., Artificial neural network analysis: A novel application for predicting site-specific bone mineral density, Acta Diabetol, 40, (2003); Kavitha M.S., Asano A., Taguchi A., Et al., Diagnosis of osteoporosis from dental panoramic radiographs using the support vector machine method in a computer-aided system, BMC Med Imaging, 12, (2012); Xu Y., Li D.S., Chen Q.L., Et al., Full supervised learning for osteoporosis diagnosis using micro-CT images, Microsc Res Tech, 76, pp. 333-341, (2013); Kavitha M.S., Kumar P.G., Park S.Y., Et al., Automatic detection of osteoporosis based on hybrid genetic swarm fuzzy classifier approaches, Dentomaxillofac Radiol, 45, (2016); Singh A., Dutta M.K., Jennane R., Et al., Classification of the trabecular bone structure of osteoporotic patients using machine vision, Comput Biol Med, 91, pp. 148-158, (2017); Scanlan J., Li F.F., Umnova O., Et al., pp. 93-100; Zhou X., Feng T., Zhan H.C., Et al.; Atkinson E.J., Therneau T.M., Melton L.J., Et al., Assessing fracture risk using gradient boosting machine (GBM) models, J Bone Miner Res, 27, pp. 1397-1404, (2012); Tseng W.J., Hung L.W., Shieh J.S., Et al., Hip fracture risk assessment: Artificial neural network outperforms conditional logistic regression in an age- and sex-matched case control study, BMC Musculoskelet Disord, 14, (2013); Yoo T.K., Kim S.K., Kim D.W., Et al., Osteoporosis risk prediction for bone mineral density assessment of postmenopausal women using machine learning, Yonsei Med J, 54, pp. 1321-1330, (2013); Zhang Y., Huang L.L., Liu Y., Et al., Prediction of mortality at one year after surgery for pertrochanteric fracture in the elderly via a Bayesian belief network, Injury-Int J Care Inj, 51, pp. 407-413, (2020); Forth K.E., Wirfel K.L., Adams S.D., Et al., A postural assessment utilizing machine learning prospectively identifies older adults at a high risk of falling, Front Med, 7, (2020)","S. Yang; Department of Orthopedic, Spinal Pain Research Institute, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China; email: 2031212@tongji.edu.cn; S. He; Department of Orthopedic, Spinal Pain Research Institute, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China; email: tjhss7418@tongji.edu.cn; X. Liao; National Key Clinical Pain Medicine of China, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China; email: digitalxiang@163.com","","SAGE Publications Inc.","","","","","","20552076","","","","English","Digit. Health","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85203515209" -"Kushwaha D.; Talib F.; Asjad M.","Kushwaha, Dilip (57215411544); Talib, Faisal (6504684729); Asjad, Mohammad (55757997800)","57215411544; 6504684729; 55757997800","The intellectual structure of research on environmental sustainability 4.0 in manufacturing: a bibliometric analysis and future research directions","2025","Environment, Development and Sustainability","","","","","","","0","10.1007/s10668-025-06495-8","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105009627311&doi=10.1007%2fs10668-025-06495-8&partnerID=40&md5=dd8fc580176c8bdd9dddf61b7718a2da","Department of Mechanical Engineering Zakir Husain College of Engineering & Technology, Faculty of Engineering & Technology, Aligarh Muslim University, Aligarh, 202002, India; Department of Mechanical Engineering, Jamia Millia Islamia, New Delhi, 110025, India","Kushwaha D., Department of Mechanical Engineering Zakir Husain College of Engineering & Technology, Faculty of Engineering & Technology, Aligarh Muslim University, Aligarh, 202002, India; Talib F., Department of Mechanical Engineering Zakir Husain College of Engineering & Technology, Faculty of Engineering & Technology, Aligarh Muslim University, Aligarh, 202002, India; Asjad M., Department of Mechanical Engineering, Jamia Millia Islamia, New Delhi, 110025, India","Manufacturing firms are paying more attention to environmental sustainability, and therefore, they intend to incorporate Industry 4.0 tools and techniques that ensure future manufacturing, product safety, and environmental sustainability. This study explores the current status and trend of environmental sustainability in manufacturing organisations in Industry 4.0 and discusses future research directions for implementing these digital tools. Therefore, this study identifies, maps, synthesises, and analyses the literature on environmental sustainability 4.0 practices in manufacturing organisations through performance analysis and science mapping. This study employed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) statement as a review norm, and information was collected as such. This paper systematically reviewed 314 English-language articles published in peer-reviewed journals in the scientific databases Scopus and the Web of Science (WOS) between 2013 and October 2023. The articles were combined, and duplicates were removed using an open-source tool, RStudio. We analysed bibliometric networks using the Biblioshiny Bibliometrix R-package in RStudio and the VOSviewer software application, which allows for creating, visualising, and interpreting maps based on any network data. This review determined the top contributing authors, nations, sources, and essential study topics. In addition, the most influential and prestigious documents based on citations and PageRank were identified and compared. Furthermore, this paper used keyword analysis to explore trends in study topics and themes and discussed the five research theme clusters obtained. Co-citation and content analysis were used to outline the intellectual structure of the discipline and pinpoint deficiencies. The gist of 49 papers inside the identified clusters is further analysed meticulously, and four primary intellectual structures were identified as Sustainable Manufacturing and Industry 4.0 relationship; Future Scope of Industry 4.0 for Sustainable Manufacturing; Impacts, Challenges, and Opportunities of Industry 4.0 for Sustainable Manufacturing; and Harmonizing Different Models with Industry 4.0: A Path to Sustainable Manufacturing. Over 50% of the scholarly work concerning environmental sustainability 4.0 within the manufacturing sector elucidates the effects, challenges, opportunities, and future possibilities of Industry 4.0. This is the first systematic literature review-cum-bibliographic study on Environmental Sustainability 4.0, which integrates three crucial issues currently being debated: Industry 4.0, environmental sustainability, and manufacturing, and provides in-depth field analysis. Based on the present review, this article suggests five potential future research issues and various research questions for investigation. New researchers may benefit from these findings and strengthen any intellectual field according to their interests and requirements. Overall, the outcomes construct an impressive starting point for additional research for decision-makers, managers, practitioners, and scholars in this domain. © The Author(s), under exclusive licence to Springer Nature B.V. 2025.","Author keywords co-occurrences; Co-citation network; Content analysis; Environmental sustainability 4.0; Industry 4.0; VOSviewer","","","","","","","","Adami L., Schiavon M., From circular economy to circular ecology: A review on the solution of environmental problems through circular waste management approaches, Sustainability MDPI AG, 13 No, 2, (2021); Adams D., Donovan J., Topple C., Achieving sustainability in food manufacturing operations and their supply chains: Key insights from a systematic literature review, Sustainable Production and Consumption, 28, pp. 1491-1499, (2021); Aghbashlo M., Peng W., Tabatabaei M., Kalogirou S., Soltanian A., Hosseinzadeh-Bandbafha S., Mahian H., Lam S., Machine learning technology in biodiesel research: A review, Progress in Energy and Combustion Science, 85, (2021); Ahirwal J., Nath A., Brahma B., Deb S., Sahoo U., Nath A., Patterns and driving factors of biomass carbon and soil organic carbon stock in the Indian Himalayan region, Science of the Total Environment, 770, (2021); Aljuaid A.A., Masood S.A., Tipu J.A., Integrating Industry 4.0 for Sustainable Localized Manufacturing to Support Saudi Vision 2030: An Assessment of the Saudi Arabian Automotive Industry Model, Sustainability, 16, 12, (2023); Amjad M.S., Rafique M.Z., Khan M.A., Leveraging optimized and cleaner production through industry 4.0, Sustainable Production and Consumption, 26, pp. 859-871, (2021); Andreou A., Fragkos P., Fotiou T., Filippidou F., Assessing lifestyle transformations and their systemic effects in Energy-System and integrated assessment models: A review of current methods and data, Energies MDPI AG, 15, 14, (2022); Appio F., Cesaroni P.F., Di Minin A., Visualizing the structure and bridges of the intellectual property management and strategy literature: A document co-citation analysis, Scientometrics, 101, 1, pp. 623-661, (2014); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11 No, 4, pp. 959-975, (2017); Aziz N., Adnan A., Wahab N.A.A., Azman A., Component design optimisation based on artificial intelligence in support of additive manufacturing repair and restoration: Current status and future outlook for remanufacturing, Journal of Cleaner Production, 296, (2021); Bahn R., Yehya A., Zurayk R., Digitalization for sustainable Agri-Food systems: Potential, status, and risks for the MENA region, Sustainability MDPI AG, 13 No, 6, (2021); Bai C., Dallasega P., Orzes G., Sarkis J., Industry 4.0 technologies assessment: A sustainability perspective, International Journal of Production Economics, 229, (2020); Beier G., Niehoff S., Ziems T., Xue B., Sustainability aspects of a digitalised industry – A comparative study from China and Germany, International Journal of Precision Engineering and Manufacturing-Green Technology, 4, 2, pp. 227-234, (2017); 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Talib; Department of Mechanical Engineering Zakir Husain College of Engineering & Technology, Faculty of Engineering & Technology, Aligarh Muslim University, Aligarh, 202002, India; email: ftalib77@gmail.com","","Springer Science and Business Media B.V.","","","","","","1387585X","","EDSNB","","English","Environ. Dev. Sustainability","Article","Article in press","","Scopus","2-s2.0-105009627311" -"Anand L.; Gayathri P.; Karuveettil V.; Anjali M.","Anand, Lekshmi (58905584000); Gayathri, P. (59391294000); Karuveettil, Vineetha (57203729825); Anjali, M. (58141641200)","58905584000; 59391294000; 57203729825; 58141641200","Top 100 most cited economic evaluation papers of preventive oral health programmes: A bibliometric analysis","2024","Journal of Oral Biology and Craniofacial Research","14","6","","802","807","5","0","10.1016/j.jobcr.2024.10.012","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207946720&doi=10.1016%2fj.jobcr.2024.10.012&partnerID=40&md5=014eb7a6a5c09ec8b3e199fd9ae01287","Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, India; Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, India","Anand L., Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, India; Gayathri P., Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, India; Karuveettil V., Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, India; Anjali M., Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, India","Objective: To identify the trends of the top 100 cited articles on economic evaluation in preventive oral health programs. Methods: Top 100 papers involving economic evaluation or cost analysis of preventive oral health programs were selected by querying Scopus and Web of Science databases. Bibliometric analysis was performed using the Bibliometrix tool in R Studio. Performance analysis and science mapping were performed for these 100 articles. Performance analysis included publication-related metrics, citation-related metrics, and citation-publication-related metrics. Science mapping provided information on citation analysis, co-citation analysis, bibliographic coupling, co-word analysis, and co-authorship details. Results: The total citation number of the top 100 most cited articles ranged from 4 to 98, with publication dates spanning from 1978 to 2023. The majority of articles (33.70 %) originated from the USA, while Community Dentistry and Oral Epidemiology stood out as the journal with the highest number of articles published in the top 100 (16 out of 100). Griffin PM emerged as the most cited author, based on the frequency measurement of the number of papers. Program data economic evaluation was the most commonly reported study design, and fluoridation programs were the most frequent topic. The most reported type of economic analysis performed in the articles was cost-effectiveness analysis. Conclusion: The bibliometric analysis of the top 100 most-cited articles on economic evaluation of preventive oral health programs revealed the lacunae in the research literature on this topic. Therefore, preventive oral health programs should be economically evaluated to eliminate the disparity in resource allocation particularly in upper middle income and low-income countries. © 2024 The Authors","Bibliometrics; Citation analysis; Cost-effectiveness; Economic evaluation; Preventive healthcare","","","","","","","","Global Oral Health Status Report: Towards Universal Health Coverage for Oral Health by 2030, (2022); Vozza I., Oral prevention and management of oral healthcare, Int J Environ Res Publ Health, 18, 4, (2021); Yule B.F., van Amerongen B.M., van Schaik M.C., The economics and evaluation of dental care and treatment, Soc Sci Med, 22, 11, pp. 1131-1139, (1986); Davidson T., Blomma C., Bagesund M., Vall M., Cost-effectiveness of caries preventive interventions-a systematic review, Acta Odontol Scand., 79, 4, pp. 309-320, (2021); Zaror C., Munoz-Millan P., Espinoza-Espinoza G., Vergara-Gonzalez C., Cost-effectiveness of adding fluoride varnish to a preventive protocol for early childhood caries in rural children with no access to fluoridated drinking water, J Dent, 1, (2020); Anopa Y., Conway D.I., Exploring the cost effectiveness of child dental caries prevention programmes.Are we comparing apples and oranges?, Evid Base Dent, 21, 1, pp. 5-7, (2020); Nguyen T.M., Tonmukayakul U., Warren E., A Markow cost-effectiveness analysis of biannual fluoride varnish for preventing dental caries in permanant teeth over a 70 year time horizon, Health Promot J Aust, 31, 2, pp. 177-183, (2020); Datta D., Sujatha A., Narayanan M.A., Kumar S.R., Leena A., Health economics–oral health care perspective, Sch. 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Karuveettil; Department of Public Health Dentistry, Amrita School of Dentistry, Kochi, Kerala, India; email: kvineetha2016@gmail.com","","Elsevier B.V.","","","","","","22124268","","","","English"," J. Oral Biol. Craniofac. Res.","Review","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85207946720" -"Vatis S.E.; Nerantzidis M.; Drogalas G.; Chytis E.","Vatis, Stylianos Efstratios (59161749100); Nerantzidis, Michail (55799436100); Drogalas, George (57199329866); Chytis, Evangelos (57215026933)","59161749100; 55799436100; 57199329866; 57215026933","Connecting IFRS and earnings management: a bibliometric analysis","2025","Journal of Accounting Literature","47","1","","51","74","23","3","10.1108/JAL-02-2023-0036","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85214033237&doi=10.1108%2fJAL-02-2023-0036&partnerID=40&md5=839354d3cc4cb97175826b76893a5a5a","Department of Accounting and Finance, University of Thessaly, Larisa, Gaiopolis, Greece; School of Social Sciences, Hellenic Open University, Patra, Greece; Department of Business and Administration, University of Macedonia, Thessaloniki, Greece; University of Ioannina, Ioannina, Greece","Vatis S.E., Department of Accounting and Finance, University of Thessaly, Larisa, Gaiopolis, Greece; Nerantzidis M., Department of Accounting and Finance, University of Thessaly, Larisa, Gaiopolis, Greece, School of Social Sciences, Hellenic Open University, Patra, Greece; Drogalas G., Department of Business and Administration, University of Macedonia, Thessaloniki, Greece; Chytis E., University of Ioannina, Ioannina, Greece","Purpose: The purpose of this study is to identify, recap and evaluate the state-of-the-art linkage between International Financial Reporting Standards (IFRS) and earnings management (EM). Design/methodology/approach: A bibliometric analysis of 249 publications from the Web of Science (WoS) database was carried out, employing both the techniques of performance analysis and science mapping and the Bibliometrix R and VOSviewer tools. Findings: The results of the performance analysis suggest that the publication and citation trends of the interplay of the IFRS and EM fields show an upward trend over time that most of the influential institutions emanate from the US and a significant percentage of articles published in this field emanate from high-quality journals. Science mapping via co-authorship analysis elucidates that more collaborative efforts among authors are needed in the future in this field. Bibliographic coupling analysis bifurcates the studies into six clusters and reveals the major themes and their evolution. Co-word analysis unfolds emerging trends that could be further explored, thus becoming possible future research avenues. Originality/value: To the best of the authors' knowledge, no other study has attempted a bibliometric analysis of research on the relationship between IFRS and EM. This article fills this research gap and makes its contribution to the scientific community by presenting recent developments in this body of knowledge and suggesting future research avenues. © 2023, Emerald Publishing Limited.","Bibliometric analysis; Bibliometrix R; Earnings management; IFRS; VOSviewer","","","","","","","","AbuGhazaleh N.M., Al-Hares O.M., Roberts C., Accounting discretion in goodwill impairments: UK evidence, Journal of International Financial Management and Accounting, 22, 3, pp. 165-204, (2011); Achleitner A.K., Gunther N., Kaserer C., Siciliano G., Real earnings management and accrual-based earnings management in family firms, European Accounting Review, 23, 3, pp. 431-461, (2014); Adhikari A., Bansal M., Kumar A., IFRS convergence and accounting quality: India a case study, Journal of International Accounting, Auditing and Taxation, 45, (2021); Agoglia C.P., Doupnik T.S., Tsakumis G.T., Principles-based versus rules-based accounting standards: the influence of standard precision and audit committee strength on financial reporting decisions, The Accounting Review, 86, 3, pp. 747-767, (2011); Ahmad G., Subhan M., Hayat F., Al-Faryan M.A.S., Unravelling the truth: a bibliometric analysis of earnings management practices, Cogent Business and Management, 10, 1, (2023); Ahmed A.S., Neel M., Wang D., Does mandatory adoption of IFRS improve accounting quality? 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[2004], Journal of Accounting Research, 42, 2, pp. 463-474, (2004); Zhu J., Song L.J., Zhu L., Johnson R.E., Visualizing the landscape and evolution of leadership research, The Leadership Quarterly, 30, 2, pp. 215-232, (2019); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","M. Nerantzidis; Department of Accounting and Finance, University of Thessaly, Gaiopolis, Larisa, Greece; email: nerantzidismike@uth.gr","","Emerald Publishing","","","","","","07374607","","","","English","J. Account. Lit.","Article","Final","","Scopus","2-s2.0-85214033237" -"Rehman I.U.; Wani J.A.; Ganaie S.A.","Rehman, Ikhlaq ur (57208900045); Wani, Javaid Ahmad (57211168037); Ganaie, Shabir Ahmad (55745889700)","57208900045; 57211168037; 55745889700","Gauging the research performance of BRICS in the domain of Library and Information Science through Performance analysis and Science mapping","2024","Journal of Librarianship and Information Science","56","4","","835","856","21","7","10.1177/09610006231173464","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85162978109&doi=10.1177%2f09610006231173464&partnerID=40&md5=91e4559758da5eb8d32b4c47a7be4d7a","University of Kashmir, India","Rehman I.U., University of Kashmir, India; Wani J.A., University of Kashmir, India; Ganaie S.A., University of Kashmir, India","The study gauges the research performance of the BRICS bloc in the field of Library and Information Science (LIS) research using Performance analysis and Science mapping. The Web of Science database is used for the study and articles published between 2013 and 2022 have been selected for analysis. Data analysis and visualisation have been done using the Bibliometrix R package and VOSviewer. The findings reveal an upward trend in publications. Furthermore, China has been the most prolific nation in terms of productivity and impact. Scientometrics is the leading source in terms of publications while the International Journal of Information Management is the most cited source. With regard to author productivity, Zhang Y has the highest number of publications while Lowry PB is the most cited author. Wuhan University is the most productive organization. In terms of collaboration, the USA is the primary partner for the entire BRICS group, particularly China and collaboration among the BRICS isn’t as significant as it is with the non-BRICS countries. This study provides insightful information about recent scientific developments in the field of LIS. Additionally, by using this research as a guide, researchers from different fields will be able to analyse how the body of knowledge on a certain subject has evolved over time. 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A comparative analysis from scientometrics perspective, Scientometrics, 94, pp. 615-628, (2013); Zeinoun P., Akl E.A., Maalouf F.T., Et al., The Arab region’s contribution to global mental health research (2009–2018): A bibliometric analysis, Frontiers in psychiatry, 11, (2020); Zhang J., Yu Q., Zheng F., Et al., Comparing keywords plus of WOS and author keywords: A case study of patient adherence research, Journal of the Association for Information Science and Technology, 67, 4, pp. 967-972, (2016); Zhang P., Du Y., Han S., Et al., Global progress in oil and gas well research using bibliometric analysis based on VOSviewer and CiteSpace, Energies, 15, 15, (2022); Zia S., An analysis of research output in open access journals in BRICS countries: A bibliometric study, Global Knowledge, Memory and Communication, 70, 8-9, pp. 911-922, (2021)","I.U. Rehman; Ikhlaq ur Rehman, Department of Library and Information Science, University of Kashmir, Srinagar 190006, India; email: ak.edu05@gmail.com","","SAGE Publications Ltd","","","","","","09610006","","","","English","J. Librariansh. Inf. Sci.","Article","Final","","Scopus","2-s2.0-85162978109" -"Asif R.; Nasir A.","Asif, Rabia (57212796681); Nasir, Adeel (55398249000)","57212796681; 55398249000","Financial stability nexus of Islamic banks: an influential and intellectual science mapping structure","2024","Journal of Islamic Accounting and Business Research","15","4","","569","589","20","3","10.1108/JIABR-07-2022-0167","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85154553711&doi=10.1108%2fJIABR-07-2022-0167&partnerID=40&md5=11019cde3dcc40c6d61f73e0f18b0de0","Department of Management Sciences, Lahore College for Women University, Lahore, Pakistan","Asif R., Department of Management Sciences, Lahore College for Women University, Lahore, Pakistan; Nasir A., Department of Management Sciences, Lahore College for Women University, Lahore, Pakistan","Purpose: This study aims to provide a comprehensive bibliometric investigation of the antecedents to financial stability in Islamic banking, a transition economy with a volatile stock market focusing on banks following the Shariah approach. Design/methodology/approach: The data for this analysis was extracted from the Scopus database, which combines a comprehensively crafted abstract and citation database with augmented data and linked scholarly works across various disciplines. It quickly finds relevant research and provides access to reliable data and analytical tools. This study deploys “bibliometrix 3.0,” a biblioshiny R-package for influential structure and the VOS viewer for intellectual structure. Findings: The investigation’s main findings revealed that 1,910 documents were published from 1987 to 2022. Published manuscripts received 39,050 citations, with an average of 10.18 citations per year. However, the instructed empirical research was experienced during 2009 and 2020, while earlier periods (1987–2008) were relatively inactive where banking was considered protective in the presence of BASEL-II capital accords regulations. While the International Journal of Bank Market has been at the top of the list to publish articles related to the area under investigation, the Journal of Banking and Finance is ranked one of the most cited articles. Malaysia has been at the top of the list of countries to research Islamic Sharia compliance principles in the banking industry, and International Islamic University Malaysia has produced enough evidence in this regard. The intellectual structure provided essential foundations for future research, and the bibliometric coupling approach was used. Practical implications: While most of the banking research has been conducted to determine the banking business efficiency, risk and profitability, little focus is given to financial stability and that too concerning the Islamic banks. Therefore, researchers need to investigate this horizon from an Islamic banking point of view and focus on key issues that discriminate between Islamic and conventional banks in determining their stability level. Originality/value: Briefly, to the best of the authors’ knowledge, this study would be the first to provide bibliometric information about financial stability keeping in view the sample data from banks with the Shariah approach. Furthermore, the proven analysis demonstrates a novel contribution that financially stable Islamic banks might strengthen the financial industry and overall economy. © 2023, Emerald Publishing Limited.","Banks; Bibliometric; Bibliometric analysis; CAMEL analysis; CAMELS; Financial stability; Islamic","","","","","","","","Abbas A., Nisar Q.A., Mahmood M.A.H., Chenini A., Zubair A., The role of Islamic marketing ethics towards customer satisfaction, Journal of Islamic Marketing, 11, 4, pp. 1001-1018, (2020); Abdul Rahman R., Masngut M.Y., The use of ‘CAMELS’ in detecting financial distress of Islamic banks in Malaysia, Journal of Applied Business Research (JABR), 30, 2, pp. 445-452, (2014); Akhtar S., Islamic banks: resilience and stability-not immune from crisis, Current Issues in Islamic Banking and Finance Resilience and Stability in the Present System, (2010); Al-Ajmi J., Hussain H.A., Al-Saleh N., Clients of conventional and Islamic banks in Bahrain: how they choose which bank to patronize, International Journal of Social Economics, 36, 11, pp. 1086-1112, (2009); Alam N., Hamid B.A., Tan D.T., Does competition make banks riskier in dual banking system?, Borsa Istanbul Review, 19, pp. S34-S43, (2019); Ali M., Puah C.-H., Does bank size and funding risk effect banks’ stability? A lesson from Pakistan, Global Business Review, 19, 5, pp. 1166-1186, (2018); Ali M., Raza S.A., Service quality perception and customer satisfaction in Islamic banks of Pakistan: the modified SERVQUAL model, Total Quality Management and Business Excellence, 28, 5-6, pp. 559-577, (2017); Almaqtari F.A., Al-Homaidi E.A., Tabash M.I., Farhan N.H., The determinants of profitability of Indian commercial banks: a panel DATA approach, International Journal of Finance and Economics, 24, 1, pp. 168-185, (2019); Alqahtani F., Mayes D.G., Financial stability of Islamic banking and the global financial crisis: evidence from the Gulf cooperation council, Economic Systems, 42, 2, pp. 346-360, (2018); Al-Rjoub S.A., A financial stability index for Jordan, Journal of Central Banking Theory and Practice, 10, 2, pp. 157-178, (2021); Alshater M.M., Hassan M.K., Khan A., Saba I., Influential and intellectual structure of Islamic finance: a bibliometric review, International Journal of Islamic and Middle Eastern Finance and Management, 14, 2, pp. 339-365, (2021); Asif R., Akhter W., Zulfiqar Z., Fiaz M., Does diversification affect financial stability? 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WALIA Journal, 34, 1, pp. 27-31, (2018); Thambiah S., Eze U.C., Tan K.S., Nathan R.J., Lai K.P., Diffusion of Islamic retail banking services among Malaysian banking consumers, Creating Global Economies through Innovation and Knowledge Management Theory and Practice - Proceedings of the 12th International Business Information Management Association Conference, pp. 190-199, (2009); Thomas A., Interest in Islamic economics: understanding Riba, Interest in Islamic Economics: Understanding Riba, (2005); Verma S., Gustafsson A., Investigating the emerging COVID-19 research trends in the field of business and management: a bibliometric analysis approach, Journal of Business Research, 118, pp. 253-261, (2020); Vozkova K., Teply P., Determinants of bank fee income in the EU banking industry -does market concentration matter?, Prague Economic Papers, 27, 1, pp. 3-20, (2018); Xu X., Chen F., Jia S., Brown Y., Gong Y.X., Supply chain finance: a systematic literature review and bibliometric analysis, International Journal of Production Economics, 204, pp. 160-173, (2018); Yuksel S., Mukhtarov S., Mammadov E., Ozsari M., Determinants of profitability in the banking sector: an analysis of Post-Soviet countries, Economies, 6, 3, (2018); Yusoff R., Wilson R., The stability of deposits in the interest-based and interest-free banking systems in Malaysia, Jurnal Ekonomi Malaysia, 43, 1, pp. 67-83, (2009); Yusuf A.A., Santi N., Rismaya E., The efficiency of Islamic banks: empirical evidence from Indonesia, Journal of Asian Finance, Economics and Business, 8, 4, pp. 239-247, (2021); Zainol Z., Kassim S.H., An analysis of Islamic banks’ exposure to rate of return risk, Journal of Economic Cooperation and Development, 31, 1, pp. 59-84, (2010); Zaki E., Bah R., Rao A., Assessing probabilities of financial distress of banks in UAE, International Journal of Managerial Finance, 7, 3, pp. 304-320, (2011); Zeqiraj V., Mrasori F., Iskenderoglu O., Sohag K., Dynamic impact of banking performance on financial stability: fresh evidence from southeastern Europe, Journal of Central Banking Theory and Practice, 10, 1, pp. 165-181, (2021)","A. Nasir; Department of Management Sciences, Lahore College for Women University, Lahore, Pakistan; email: adeel.nasir@lcwu.edu.pk","","Emerald Publishing","","","","","","17590817","","","","English","J. Islamic Account. Bus. Res.","Article","Final","","Scopus","2-s2.0-85154553711" -"Kum G.; Berglund O.; Hollander J.","Kum, Gina (57189507707); Berglund, Olof (7004101123); Hollander, Johan (56185235900)","57189507707; 7004101123; 56185235900","Lost in definition: unravelling microplastics from marine coatings through bibliometrics science mapping in thematic analysis and systematic narrative literature review","2025","Environmental Sciences Europe","37","1","38","","","","1","10.1186/s12302-025-01070-4","https://www.scopus.com/inward/record.uri?eid=2-s2.0-86000773516&doi=10.1186%2fs12302-025-01070-4&partnerID=40&md5=27daca4fdb92902420747ef46636b781","World Maritime University, Malmö, 211 18, Sweden; Department of Biology, Lund University, Lund, 221 00, Sweden; Ocean Sustainability, Governance & Management Unit, World Maritime University, Malmö, 211 18, Sweden","Kum G., World Maritime University, Malmö, 211 18, Sweden; Berglund O., Department of Biology, Lund University, Lund, 221 00, Sweden; Hollander J., Ocean Sustainability, Governance & Management Unit, World Maritime University, Malmö, 211 18, Sweden","Marine coatings used on merchant ships have recently emerged as a source of microplastics in marine environments. Marine coatings encompass all paints and coatings applied to various parts of a ship, primarily for anti-corrosion, antifouling anti-skid, heat-resistance, and cosmetic enhancement. However, marine coatings on merchant ships have evaded classification and were not included in the microplastic literature until recently. The purpose of this study is to examine the current state of the absence of a unified definition on a global scale, identify the factors that contribute to the exclusion of marine coatings under the microplastic classification and to analyse the thematic mapping and evolution of the keywords “definition”, “classification”, and “paint” or “marine coatings” in the field of microplastics. We conducted science mapping analysis using Bibliometrix software to examine 1078 papers and carried out a systematic narrative literature review to examine the current state of a standardised definition of microplastics and whether the absence of such impedes a unified interpretation and study of microplastics from marine coatings. Based on the science mapping analysis, this research indicates that “definition” and “paint” have become important keywords in the domain of microplastic research lately, playing a vital role in structuring the field. Meanwhile, the systematic narrative literature review unveiled that the absence of a standardised definition remains a subject of considerable debate, resulting in marine coatings evading classification as microplastics. With this study, we aim to advocate for the establishment of more precise guidelines and policies pertaining to microplastic pollution in marine environments and to promote the adoption of a unified approach towards the definition and classification of microplastics for the purposes of legislation and research. This will also path the way for the collection of better data on microplastic emissions from marine coatings, thereby closing the knowledge gap in this area. © The Author(s) 2025.","Antifouling paint; Classification; Definition; Marine coatings; Microplastics; Shipping","Antireflection coatings; Corrosion resistant coatings; Mapping; Marine pollution; Seawater corrosion; Ships; 'current; Anti-foulings; Bibliometric; Definition; Literature reviews; Mapping analysis; Marine coatings; Marine environment; Merchant ships; Microplastics; antifouling; classification; coating; literature review; marine pollution; nanoparticle; plastic; qualitative analysis; research work; shipping; Antifouling paint","","","","","Naturvårdsverket, NVV; National Institute for Public Health and the Environment, Netherlands; Miljø- og Fødevareministeriet, mfvm; Norwegian Environmental Agency; Umweltbundesamt, UBA; Lunds Universitet, LU; Rijksinstituut voor Volksgezondheid en Milieu, RIVM; Nippon Foundation of Japan","Funding text 1: Six papers at both international and regional levels of regulatory bodies that consider marine coatings have been published by or on behalf of organisations, such as GESAMP [, ], the International Union for Conservation of Nature and Natural Resources (IUCN) [], the European Commission [, ], and the International Maritime Organisation (IMO) [] As far as we are aware, GESAMP [] is the first paper that recognised marine coatings as a secondary source of microplastics for a regulatory body at international level and in their definition of plastics in marine debris include thermoset materials such as epoxy resins and some coatings films. Additionally, national-level reports have been produced by the Norwegian Environmental Agency [], the Federal Environment Agency, Germany [], the Ministry of Environment and Food, Denmark [], the National Institute for Public Health and the Environment, Netherlands (RIVM) [], and the Swedish Environmental Protection Agency []. ; Funding text 2: Open access funding provided by Lund University. Hempel provide funding for G.K\u2019s doctoral studies as stated in acknowledgements.; Funding text 3: GK acknowledges financial support received from Hempel. Whilst Hempel provided funding for G.K.'s doctoral studies, this support did not influence the study's design, data collection, analysis, interpretation, or reporting. This research was conducted independently to maintain scientific integrity and objectivity. J.H. acknowledges the generous support by the Nippon Foundation of Japan. 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Kum; World Maritime University, Malmö, 211 18, Sweden; email: w1011666@wmu.se; O. Berglund; Department of Biology, Lund University, Lund, 221 00, Sweden; email: olof.berglund@biol.lu.se","","Springer","","","","","","21904707","","","","English","Env. Sci. Eur.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-86000773516" -"Ngamake S.T.; Raveepatarakul J.; Sawang S.","Ngamake, Sakkaphat T. (55110355800); Raveepatarakul, Jirapattara (56095471000); Sawang, Sukanlaya (16403499100)","55110355800; 56095471000; 16403499100","An Evolving Landscape of the Psychology of Judgment and Decision-Making: A Bibliometric Analysis","2024","Administrative Sciences","14","8","162","","","","0","10.3390/admsci14080162","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85202596751&doi=10.3390%2fadmsci14080162&partnerID=40&md5=1eefeb2c77db2e716756f48b6c3750d0","Faculty of Psychology, Chulalongkorn University, Bangkok, 10330, Thailand; The Business School, Edinburgh Napier University, Edinburgh, EH14 1DJ, United Kingdom","Ngamake S.T., Faculty of Psychology, Chulalongkorn University, Bangkok, 10330, Thailand; Raveepatarakul J., Faculty of Psychology, Chulalongkorn University, Bangkok, 10330, Thailand; Sawang S., The Business School, Edinburgh Napier University, Edinburgh, EH14 1DJ, United Kingdom","As a discipline with an expansive and intricate landscape, the field of judgment and decision-making (JDM) has evolved significantly since the beginning of the 2020s. The extensive and intricate nature of this field might pose challenges for scholars and researchers in designing course content and curricula as well as in defining research boundaries. Several techniques from a bibliometric study, such as co-word analysis and co-citation analysis, can provide insights into the scopes and directions of the field. Previous bibliometric studies on the psychology of JDM have primarily analyzed published documents restricted either by content areas or by journal outlets. The present study attempts to analyze a collection of published documents with broad search terms (i.e., “judgment*” or “decision mak*”) within the purview of the psychology subject area, separately by years of publication (from 2020 to 2022) using the bibliometrix package in the R environment. The most relevant journals and the most frequent keywords have suggested established areas of study, uncovering common themes, patterns, and trends. Beyond that, two science mapping techniques (i.e., keyword co-occurrence network and reference co-citation network) revealed 12 prominent themes that cut across the three-year period. These themes, alongside other intellectually stimulating issues, were discussed based on a comparison with outstanding book chapters and reviews. Implications for pedagogical purposes were also provided with a handful of notable resources. © 2024 by the authors.","applied psychology; bibliometrics; JDM; judgment and decision-making; psychology","","","","","","Psychology Center for Life-Span Development and Intergeneration; Chulalongkorn University, CU, (1384208000)","This project has been granted funds from Psychology Center for Life-Span Development and Intergeneration, Chulalongkorn University, The Second Century Fund (C2F): grant number 1384208000.","Ajzen I., The theory of planned behavior, Organizational Behavior and Human Decision Processes, 50, pp. 179-211, (1991); Akosah-Twumasi P., Emeto T., Lindsay D., Tsey K., Malau-Aduli B., A systematic review of factors that influence youths career choices–the role of culture, Frontiers in Education, 3, (2018); Diagnostic and Statistical Manual of Mental Disorders: DSM-5, (2013); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, pp. 959-975, (2017); Augier M., Simon says: Bounded rationality matters, Journal of Management Inquiry, 10, pp. 268-275, (2001); Bandura A., Social foundations of thought and action, The Health Psychology Reader, pp. 94-106, (1986); Bandura A., Self-Efficacy: The Exercise of Control, (1997); Barcellos-Paula L., de La Vega I., Gil-Lafuente A., Bibliometric review of research on decision models in uncertainty, 1990–2020, International Journal of Intelligent Systems, 37, pp. 7300-7333, (2022); Barrios V., Khaw L., Bermea A., Hardesty J., Future directions in intimate partner violence research: An intersectionality framework for analyzing women’s processes of leaving abusive relationships, Journal of Interpersonal Violence, 36, pp. NP12600-NP12625, (2021); Bartels D.M., Bauman C.W., Cushman F.A., Pizarro D.A., McGraw A.P., Moral judgment and decision making, The Wiley Blackwell Handbook of Judgment and Decision Making, pp. 478-515, (2015); Bates D., Machler M., Bolker B., Walker S., Fitting linear mixed-effects models using lme4, Journal of Statistical Software, 67, pp. 1-48, (2015); Bechara A., Damasio A., Damasio H., Anderson S., Insensitivity to future consequences following damage to human prefrontal cortex, Cognition, 50, pp. 7-15, (1994); Betz N.E., Klein K.L., Taylor K.M., Evaluation of a short form of the Career Decision-Making Self-Efficacy Scale, Journal of Career Assessment, 4, pp. 47-57, (1996); Bian X., Career indecision: An integrative review and research agenda, European Journal of Training and Development, 47, pp. 166-182, (2023); Botvinick M., Braver T., Motivation and cognitive control: From behavior to neural mechanism, Annual Review of Psychology, 66, pp. 83-113, (2015); Brashier N.M., Marsh E.J., Judging truth, Annual Review of Psychology, 71, pp. 499-515, (2020); Braun V., Clarke V., Using thematic analysis in psychology, Qualitative Research in Psychology, 3, pp. 77-101, (2006); Brown S.D., Lent R.W., Vocational psychology: Agency, equity, and well-being, Annual Review of Psychology, 67, pp. 541-565, (2016); Buss D.M., Schmitt D.P., Mate preferences and their behavioral manifestations, Annual Review of Psychology, 70, pp. 77-110, (2019); Cai Y., Jin F., Liu J., Zhou L., Tao Z., A survey of collaborative decision-making: Bibliometrics, preliminaries, methodologies, applications and future directions, Engineering Applications of Artificial Intelligence, 122, (2023); Chapman G.B., A decision-science approach to health-behavior change, Current Directions in Psychological Science, 28, pp. 469-474, (2019); Charmaz K., Constructing Grounded Theory, (2014); Clatch L., Walters A., Borgida E., How interdisciplinary? 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Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, pp. 429-472, (2015)","S.T. Ngamake; Faculty of Psychology, Chulalongkorn University, Bangkok, 10330, Thailand; email: sakkaphat.n@chula.ac.th","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20763387","","","","English","Adm. Sci.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85202596751" -"Zhang X.; Kong W.; Shi R.; Sun L.; Xu M.; Gong L.","Zhang, Xiyue (59707111400); Kong, Weimin (59961735800); Shi, Rongfen (59304056700); Sun, Long (59706906300); Xu, Min (59308895800); Gong, Ling (59706906400)","59707111400; 59961735800; 59304056700; 59706906300; 59308895800; 59706906400","Data-driven trends in critical care informatics: a bibliometric analysis of global collaborations using the MIMIC database (2004–2024)","2025","Computers in Biology and Medicine","195","","110670","","","","0","10.1016/j.compbiomed.2025.110670","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105008948656&doi=10.1016%2fj.compbiomed.2025.110670&partnerID=40&md5=b57cc410caca49d91cde7d659203febb","Nursing Department, The Affiliated Jiangning Hospital of Nanjing Medical University, Jiangsu, Nanjing, 211100, China; Endocrinology Department, Yancheng First Hospital Affiliated Hospital of Nanjing University Medical School, Yancheng, 224000, China; Endocrinology Department, Yancheng No 1 People's Hospital, Yancheng, 224000, China","Zhang X., Nursing Department, The Affiliated Jiangning Hospital of Nanjing Medical University, Jiangsu, Nanjing, 211100, China; Kong W., Endocrinology Department, Yancheng First Hospital Affiliated Hospital of Nanjing University Medical School, Yancheng, 224000, China, Endocrinology Department, Yancheng No 1 People's Hospital, Yancheng, 224000, China; Shi R., Nursing Department, The Affiliated Jiangning Hospital of Nanjing Medical University, Jiangsu, Nanjing, 211100, China; Sun L., Nursing Department, The Affiliated Jiangning Hospital of Nanjing Medical University, Jiangsu, Nanjing, 211100, China; Xu M., Nursing Department, The Affiliated Jiangning Hospital of Nanjing Medical University, Jiangsu, Nanjing, 211100, China; Gong L., Nursing Department, The Affiliated Jiangning Hospital of Nanjing Medical University, Jiangsu, Nanjing, 211100, China","Background: The Medical Information Mart for Intensive Care (MIMIC) database has become a cornerstone resource for critical care research, enabling advances in outcome prediction, machine learning, and patient management. However, comprehensive bibliometric understanding of MIMIC-related research evolution, global collaboration, and thematic trends remains limited. Objective: This study aimed to perform a comprehensive bibliometric analysis of MIMIC-related publications (2004–2024), identifying thematic evolution, global research trends, and emerging areas, to guide future research directions. Methods: We conducted a bibliometric analysis of 2769 MIMIC-related publications indexed in the Web of Science Core Collection. Eligible peer-reviewed articles and reviews in English were screened through a dual-blinded process. Bibliometric analyses were performed using multiple software tools: R (v4.4.3) with RStudio (v2024.12.1 + 563) for data cleaning, disambiguation, and visualization; Bibliometrix (v4.3.2) for metadata extraction, descriptive statistics, and science mapping; VOSviewer (v1.6.20) for keyword co-occurrence, clustering, and citation network analyses; and Pajek (v6.01) for large-scale network visualization and layout optimization. A multi-step disambiguation strategy was applied to ensure data consistency in author and institution names. Citation metrics, thematic clustering, temporal keyword trends, and collaboration networks were comprehensively assessed to elucidate research dynamics. Results: Among the 2769 analyzed publications, 2747 (99.2 %) were peer-reviewed original research articles. The average annual publication growth rate was 40.6 %, with an average citation rate of 11.29 per article. Publication trends showed three phases: slow growth (2004–2015), rapid expansion (2016–2020) following updated MIMIC dataset releases, and sustained momentum (2021–2024). Major journals publishing MIMIC research included Scientific Reports, Frontiers in Medicine, Frontiers in Cardiovascular, and others. China was the most productive country with 1998 publications, led by institutions such as Zhejiang University, Jinan University, and Wenzhou Medical University; however, its international collaboration rate was relatively low. In contrast, the United States demonstrated strong global influence, dominating highly cited publications and fostering extensive international collaborations. Thematic clustering and keyword co-occurrence analysis revealed an evolution in MIMIC-based research, transitioning from early descriptive studies to increasingly sophisticated applications of machine learning (ML) and artificial intelligence (AI). Foundational highly cited articles from US institutions highlighted the pivotal role of deep learning models and open-access ICU databases in critical care informatics. Conclusions: MIMIC-based research has grown substantially, with China and the U.S. leading in output and impact. Studies have evolved from descriptive analyses to advanced AI applications, yet real-world integration remains limited by issues like single-center data and model opacity. Addressing these gaps will require transparent, clinically relevant models and stronger cross-national collaboration. Aligning technical innovation with ethical and practical considerations will enhance the translational value of MIMIC research in critical care. © 2025","Bibliometric analysis; Critical care informatics; Data visualization; Health informatic; MIMIC database","Clustering algorithms; Data mining; Growth rate; Information management; Large datasets; Mapping; Medical computing; Medical informatics; Medicine; Metadata; Publishing; Statistics; Visualization; Bibliometrics analysis; Critical care; Critical care informatic; Global collaboration; Health informatics; Informatics; Intensive care; Machine-learning; Medical information; Medical information mart for intensive care database; Data visualization","","","","","Medical Information Mart for Intensive Care; Massachusetts Institute of Technology, MIT; Jiangsu Province Nanjing Municipal Special Project for Health Science and Technology Development, (YKK21229); Beth Israel Deaconess Medical Center at Harvard Medical School, (5,6)","Funding text 1: The Medical Information Mart for Intensive Care (MIMIC) database, established in 2003 through a collaboration between the Massachusetts Institute of Technology (MIT), the Beth Israel Deaconess Medical Center at Harvard Medical School, and Philips Healthcare, has emerged as a transformative resource in this field [5,6]. MIT contributed computational infrastructure, Harvard provided de-identified clinical records spanning from 2001 to 2022, and Philips supported technical integration [ 5\u20137]. With its rich multimodal data\u2014including vital signs, laboratory results, and clinician notes\u2014MIMIC has facilitated advances in predictive modeling, clinical decision support, and artificial intelligence (AI)-driven diagnostics [ 5\u20137]. Numerous recent studies have substantiated the utility of MIMIC in developing machine learning algorithms for outcome prediction across a wide range of critical care scenarios, including heart failure [8], sepsis detection [9], acute kidney injury trajectories in septic patients [10], ICU readmission or mortality risk [11], and mortality in acute pancreatitis patients [12]. These examples underscore the translational value of MIMIC in supporting data-driven, patient-centered decision-making. Its widespread availability and multimodal structure have made MIMIC not only a research resource but also a practical tool for improving patient care, advancing medical education, and supporting clinical decision-making. For patients, MIMIC has enabled the development of predictive models for outcomes such as sepsis, acute kidney injury, and ICU readmission, allowing earlier identification of high-risk individuals and more personalized interventions [ 9\u201311]. For healthcare researchers, it provides a rich, reproducible platform for studying real-world disease patterns, testing machine learning algorithms, and developing optimal treatment strategies [5,13]. By providing open access to de-identified patient records, MIMIC enables clinicians and educators to engage with real-world high-resolution ICU data, offering enhanced training opportunities, reproducible case studies, and access to resources that support clinical skill development and foster data literacy among healthcare professionals [5].The research was supported by the Jiangsu Province Nanjing Municipal Special Project for Health Science and Technology Development (YKK21229).The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Long Sun reports financial support was provided by Nanjing Municipal Health Commission. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.; Funding text 2: The research was supported by the Jiangsu Province Nanjing Municipal Special Project for Health Science and Technology Development ( YKK21229 ).","Rodemund N., Wernly B., Jung C., Cozowicz C., Kokofer A., Harnessing big data in critical care: exploring a new European dataset, Sci. Data, 11, 1, (2024); Esper A.M., Arabi Y.M., Cecconi M., Du B., Giamarellos-Bourboulis E.J., Juffermans N., Machado F., Peake S., Phua J., Rowan K., Suh G.Y., Martin G.S., Systematized and efficient: organization of critical care in the future, Crit. Care, 26, 1, (2022); Luo J., Wu M., Gopukumar D., Zhao Y., Big data application in biomedical research and health care: a literature review, Biomed. Inf. 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Data, 6, 1, (2019); Wu W.T., Li Y.J., Feng A.Z., Li L., Huang T., Xu A.D., Lyu J., Data mining in clinical big data: the frequently used databases, steps, and methodological models, Military Med. Res, 8, 1, (2021); Neto A.S., Deliberato R.O., Johnson A.E.W., Bos L.D., Amorim P., Pereira S.M., Cazati D.C., Cordioli R.L., Correa T.D., Pollard T.J., Schettino G.P.P., Timenetsky K.T., Celi L.A., Pelosi P., de Abreu M.G., Schultz M.J., Mechanical power of ventilation is associated with mortality in critically ill patients: an analysis of patients in two observational cohorts, Intensive Care Med., 44, 11, pp. 1914-1922, (2018); Desautels T., Calvert J., Hoffman J., Jay M., Kerem Y., Shieh L., Shimabukuro D., Chettipally U., Feldman M.D., Barton C., Wales D.J., Das R., Prediction of sepsis in the intensive care unit with minimal electronic health record data: a machine learning approach, JMIR Med. 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Internet Res., 26, (2024); Schouten B., Schinkel M., Boerman A.W., van Pijkeren P., Thode M., van Beneden M., Nannan Panday R., de Jonge R., Wiersinga W.J., Nanayakkara P.W.B., Implementing artificial intelligence in clinical practice: a mixed-method study of barriers and facilitators, J. Med. Artificial Intell., 5, (2022)","L. Sun; Nursing department, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, No. 169, Hushan Road, Jiangning District, Jiangsu, 211100, China; email: sunlong.harry@gmail.com","","Elsevier Ltd","","","","","","00104825","","CBMDA","","English","Comput. Biol. Med.","Article","Final","","Scopus","2-s2.0-105008948656" -"Özdoğan Sarıkoç G.","Özdoğan Sarıkoç, Gülhan (58042635200)","58042635200","Artificial intelligence applications in the field of streamflow: a bibliometric analysis of recent trends","2024","Hydrological Sciences Journal","69","9","","1141","1157","16","1","10.1080/02626667.2024.2356006","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85195265363&doi=10.1080%2f02626667.2024.2356006&partnerID=40&md5=4962ba875f8a21914895d20adca8bd81","Department of Vegetable and Animal Production, Suluova Vocational School, Amasya University, Amasya, Turkey","Özdoğan Sarıkoç G., Department of Vegetable and Animal Production, Suluova Vocational School, Amasya University, Amasya, Turkey","In this study, a bibliometric analysis technique is used for performance analysis and science mapping of artificial intelligence (AI) applications in streamflow research. This paper examines the current trends in the literature using the Scopus database over the last 37 years. RStudio Bibliometrix software was used to analyse the titles, keywords, abstracts, and full texts of 3000 publications to identify trends in AI models, publication types, journals, citations, authors, countries, and regions. The highest frequency AI-related keyword is “artificial neural networks,” which was used in a total of 25587 times. The most common publication type, at 82.1%, is journal articles, and the highest rate of country production is 25% for China. In recent years, streamflow research studies have significantly increased their use of AI applications. © 2024 IAHS.","artificial intelligence; bibliometric; research trends; RStudio Bibliometrix; Scopus; streamflow","China; Stream flow; 'current; Analysis techniques; Bibliometric; Bibliometrics analysis; Performances analysis; Recent trends; Research trends; Rstudio bibliometrix; Scopus; Streamflow; artificial intelligence; bibliography; publishing; research work; streamflow; trend analysis; Neural networks","","","","","","","Adamowski J.F., Development of a short-term river flood forecasting method for snowmelt driven floods based on wavelet and cross-wavelet analysis, Journal of Hydrology, 353, 3-4, pp. 247-266, (2008); Adisa O.M., Et al., Bibliometric analysis of methods and tools for drought monitoring and prediction in Africa, Sustainability (Switzerland), 12, 16, (2020); Adnan R.M., Et al., Streamflow forecasting using artificial neural network and support vector machine models, American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS), 29, 1, pp. 286-294, (2017); 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Özdoğan Sarıkoç; CONTACT Gülhan Özdoğan Sarıkoç, Department of Vegetable and Animal Production, Suluova Vocational School, Amasya University, Amasya, Turkey; email: ozdogan.gulhan@gmail.com","","Taylor and Francis Ltd.","","","","","","02626667","","HSJOD","","English","Hydrol. Sci. J.","Article","Final","","Scopus","2-s2.0-85195265363" -"Ishrath N.; Rajendran B.G.","Ishrath, Nadiya (59460352900); Rajendran, Bivina Geetha (57195420261)","59460352900; 57195420261","Exploring trends and patterns in traffic safety culture of pedestrians: a bibliometric analysis","2024","SN Social Sciences","4","10","186","","","","0","10.1007/s43545-024-00981-y","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85211104156&doi=10.1007%2fs43545-024-00981-y&partnerID=40&md5=924dc2e49b16692352c5cefb61989779","Department of Civil Engineering, Maulana Azad National Institute of Technology, Madhya Pradesh, Bhopal, 462003, India","Ishrath N., Department of Civil Engineering, Maulana Azad National Institute of Technology, Madhya Pradesh, Bhopal, 462003, India; Rajendran B.G., Department of Civil Engineering, Maulana Azad National Institute of Technology, Madhya Pradesh, Bhopal, 462003, India","The present study utilizes a science-mapping methodology to conduct a systematic bibliometric analysis of studies published before 2023 in the domain of pedestrian traffic safety culture. A total of 47 papers related to pedestrian safety were retrieved from Dimensions database. Initially, a comprehensive descriptive analysis was conducted, encompassing countries, sources, affiliations, most-cited papers, the most productive authors, and the entire years of publications. The cultural educational, and conceptual structures of pedestrian-safety research were subsequently classified by science mapping using the VOSviewer and Bibliometrix R-package tools. Four clusters were identified based on the intellectual structure, each defining a unique perspective within the pedestrian traffic safety culture. The clusters are “Pedestrian Behaviour and cross-cultural road safety”, “Pedestrian safety and behaviour research”, “Psychosocial factors in pedestrian safety”, and “Cross-cultural studies on adolescent pedestrian behaviour”. Four other major clusters were also identified based on the co-occurrence network: “Public health and urban planning”, “Built environment and motor activities in older adults”, “Comprehensive Insights into Pedestrian Safety: Cultural, Behavioral, and Environmental Dimensions”, and “Urban pedestrian dynamics”. The study serves as a valuable resource for researchers and policymakers aiming to enhance pedestrian safety and promote more inclusive urban environments. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024.","Pedestrian aggressiveness; Pedestrian attitude; Pedestrian behaviour; Pedestrian perception; Pedestrian safety","","","","","","","","Aceves-Gonzalez C., Ekambaram K., Rey-Galindo J., Rizo-Corona L., The role of perceived pedestrian safety on designing safer built environments, Traffic Inj Prev, 21, sup1, pp. S84-S89, (2020); Antic B., Pesic D., Milutinovic N., Maslac M., Pedestrian behaviours: validation of the Serbian version of the pedestrian behaviour scale, Transp Res part F: Traffic Psychol Behav, 41, pp. 170-178, (2016); Arellana J., Alvarez V., Oviedo D., Guzman L.A., Walk this way: pedestrian accessibility and equity in Barranquilla and Soledad, Colombia, Res Transp Econ, 86, (2021); Avinash C., Jiten S., Arkatkar S., Gaurang J., Manoranjan P., Evaluation of pedestrian safety margin at mid-block crosswalks in India, Saf Sci, 119, pp. 188-198, (2019); Banerjee A., Das S., Maurya A.K., Behavioural characteristics influencing walking speed of pedestrians over elevated facilities: a case study of India, Transp Policy, 147, pp. 169-182, (2024); Bansal A., Goyal T., Sharma U., Pedestrian Safety on Crosswalks in India–Need of the Hour, (2018); Bazargan H.S., Haghighi M., Heydari S.T., Soori H., Shahkolai F.R., Motevalian S.A., Mohammadkhani M., Developing and validating a measurement tool to self-report pedestrian safety-related behavior: the pedestrian behavior questionnaire (PBQ), Bull Emerg Trauma, 8, 4, (2020); Bernhoft I.M., Carstensen G., Preferences and behaviour of pedestri- ans and cyclists by age and gender, Transp Res Part F: Traffic Psy- chology Behav, 11, 2, pp. 83-95, (2008); Brownson R.C., Hoehner C.M., Day K., Forsyth A., Sallis J.F., Measuring the built environment for physical activity: state of the science, Am J Prev Med, 36, 4, pp. S99-S123, (2009); Cao S., Zhang J., Salden D., Ma J., Zhang R., Pedestrian dynamics in single-file movement of crowd with different age compositions, Phys Rev E, 94, 1, (2016); Chan E.T., Li T.E., Schwanen T., Banister D., People and their walking environments: an exploratory study of meanings, place and times, Int J Sustainable Transp, 15, 9, pp. 718-729, (2021); Chen C., Lin H., Loo B.P., Exploring the impacts of safety culture on immigrants’ vulnerability in non-motorized crashes: a cross-sectional study, J Urb Health, 89, pp. 138-152, (2012); Chen J., Lai T.F., Lin C.Y., Hsueh M.C., Park J.H., Liao Y., Associations between objectively measured overall and intensity-specific physical activity and phase angle in older adults, Sci Rep, 14, 1, (2024); Cinnamon J., Schuurman N., Hameed S.M., Pedestrian injury and human behaviour: observing road-rule violations at high-incident intersections, PLoS ONE, 6, 6, (2011); Esmaeli S., Aghabayk K., Abrari Vajari M., Stephens A.N., Development of the pedestrian anger expres-sion inventory, Traffic Inj Prev, 22, 2, pp. 167-172, (2021); Feng Y., Duives D., Daamen W., Hoogendoorn S., Data collection methods for studying pedestrian behaviour: a systematic review, Build Environ, 187, (2021); Guell C., Panter J., Jones N.R., Ogilvie D., Towards a differentiated understanding of active travel behav-iour: using social theory to explore everyday commuting, Soc Sci Med, 75, 1, pp. 233-239, (2012); Hashemiparast M., Montazeri A., Nedjat S., Negarandeh R., Sadeghi R., Hosseini M., Garmaroudi G., Pedestrian road-crossing behaviours: a protocol for an explanatory mixed methods study, Global J Health sci-ence, 8, 5, (2016); Hashemiparast M., Montazeri A., Nedjat S., Negarandeh R., Sadeghi R., Garmaroudi G., Pedestrian road crossing behavior (PEROB): development and psychometric evaluation, Traffic Inj Prev, 18, 3, pp. 281-285, (2017); Hashemiparast M., Negarandeh R., Montazeri A., How young pedestrians do explain their risky road crossing behaviors? 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Rajendran; Department of Civil Engineering, Maulana Azad National Institute of Technology, Bhopal, Madhya Pradesh, 462003, India; email: bivinagr@manit.ac.in","","Springer Nature","","","","","","26629283","","","","English","SN Social Sci.","Review","Final","","Scopus","2-s2.0-85211104156" -"Usman B.M.; Johl S.K.; Khan P.A.","Usman, Bashir Mikail (59178729900); Johl, Satirenjit Kaur (55792131200); Khan, Parvez Alam (59971802400)","59178729900; 55792131200; 59971802400","Fusion of green governance for sustainable development and world ecology: A tempting systematic review and bibliometric analysis","2024","Journal of Open Innovation: Technology, Market, and Complexity","10","3","100309","","","","9","10.1016/j.joitmc.2024.100309","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196428945&doi=10.1016%2fj.joitmc.2024.100309&partnerID=40&md5=34c2f264cbd22b46f4cff2ed55e8601f","Department of Management and Humanities, Universiti Teknologi PETRONAS, Seri Iskandar, 32610, Malaysia","Usman B.M., Department of Management and Humanities, Universiti Teknologi PETRONAS, Seri Iskandar, 32610, Malaysia; Johl S.K., Department of Management and Humanities, Universiti Teknologi PETRONAS, Seri Iskandar, 32610, Malaysia; Khan P.A., Department of Management and Humanities, Universiti Teknologi PETRONAS, Seri Iskandar, 32610, Malaysia","The current research contributes to sustainable development and world ecology by identifying key areas, current dynamics, and key organizations' contributors and providing significant directions toward future research on the relationship between Green Governance (GG) and Firm Performance (FP). This study carried out bibliometric systematized research using the keywords “Green Governance” AND “Firm Performance” from the Scopus database, of which 238 scientific papers were retrieved between 2002 and 2022. The assessment was conducted using inclusion and exclusion eligibility criteria adopted from the PRISMA 2022 flow diagram, which illustrates the sequential progression of information throughout various stages of a systematic review. Therefore, 209 research were analyzed using the Biblioshiny (Bibliometrix R package) for the science mapping workflow. The study found that the major research focus in this area is around firm performance, environmental management, environmental performance, and ""sustainability followed sequentially are the prominent research topics in this field. The findings further revealed that there had been a 21% drop in publication in recent years. Undoubtedly, there is growing research, especially by renowned authors on exploring the impact on firm performance. The major studies are conducted in China and the United States, engaged in the most significant collaboration. At the same time, the impact on most countries in Africa, South America, and a few in Asia is minute. Lastly, this study has also proposed five reasonable research directions based on the identified research gaps and the research framework for future analysis. © 2024 The Authors","And firm performance; Climate change governance; Ecological governance; Environmental governance; Environmental management; Green governance","","","","","","Nigerian Petroleum Technology Development Fund; Universiti Teknologi Petronas, Malaysia","This research was supported by the Nigerian Petroleum Technology Development Fund and Universiti Teknologi Petronas, Malaysia. 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Clean. Prod., (2024)","S.K. Johl; Department of Management and Humanities, Universiti Teknologi PETRONAS, Seri Iskandar, 32610, Malaysia; email: satire@utp.edu.my","","Elsevier B.V.","","","","","","21998531","","","","English","J. Open Innov.: Technol. Mark. Complex.","Review","Final","","Scopus","2-s2.0-85196428945" -"Doğan E.; Şahin F.","Doğan, Ezgi (57216603730); Şahin, Ferhan (57222560071)","57216603730; 57222560071","Advances in Artificial Intelligence in Education: Leading Contributors, Current Hot Topics, and Emerging Trends","2024","Participatory Educational Research","11","","","95","113","18","0","10.17275/per.24.96.11.6","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85217052455&doi=10.17275%2fper.24.96.11.6&partnerID=40&md5=7d6f6f2e0219544110c193b4c1ea58a6","Measurement and Evaluation, Van Yüzüncü Yıl University, Van, Turkey; Special Education, Ağrı İbrahim Çeçen University, Ağrı, Turkey","Doğan E., Measurement and Evaluation, Van Yüzüncü Yıl University, Van, Turkey; Şahin F., Special Education, Ağrı İbrahim Çeçen University, Ağrı, Turkey","Artificial Intelligence (AI) has emerged as a burgeoning field in education, characterized by rapid growth and diverse research interests. This study employs bibliometric analysis to explore the landscape of AI research in education, focusing on studies indexed in the Web of Science (WOS) database. A comprehensive search identified 1383 articles published between 1981 and 2024, which were analysed using the Bibliometrix R package. The analysis encompassed performance analysis, science mapping, and network analysis, yielding visualizations such as annual scientific production trends, most cited documents, and thematic maps. Key findings reveal a substantial increase in AI research from 2022 onwards, underscoring a shift towards longitudinal studies to track AI's evolution and impacts in educational contexts. Ethical considerations, data privacy, and societal implications emerged as critical areas requiring further investigation. While early studies focused on intelligent tutoring systems, contemporary research highlights topics like ChatGPT, machine learning, and higher education. The interdisciplinary nature of AI in education is evident through its publication in journals spanning educational technology and related fields. Future research directions emphasize the need for comprehensive studies addressing ethical frameworks and guidelines for responsible AI integration in education. Bridging technological advancements with pedagogical strategies is essential for developing integrative models that enhance personalized learning and educational outcomes. Ongoing bibliometric analyses will play a pivotal role in identifying emerging trends and guiding future research endeavours in AI and education. © 2024, Ozgen Korkmaz. All rights reserved.","artificial intelligence; bibliometrics; education; network analysis; performance analysis; science mapping","","","","","","","","Amarathunga B., ChatGPT in education: unveiling frontiers and future directions through systematic literature review and bibliometric analysis, Asian Education and Development Studies, 13, 5, pp. 412-431, (2024); Andersen N., Mapping the expatriate literature: A bibliometric review of the field from 1998 to 2017 and identification of current research fronts, The International Journal of Human Resource Management, 32, 22, pp. 4687-4724, (2021); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Arruda H., Silva E. R., Lessa M., Proenca D., Bartholo R., VOSviewer and bibliometrix, Journal of the Medical Library Association: JMLA, 110, 3, (2022); Azevedo R., Moos D. C., Greene J. A., Winters F. I., Cromley J. G., Why is externally-facilitated regulated learning more effective than self-regulated learning with hypermedia?, Educational Technology Research and Development, 56, pp. 45-72, (2008); Bower M., Torrington J., Lai J. W., Petocz P., Alfano M., How should we change teaching and assessment in response to increasingly powerful generative Artificial Intelligence? Outcomes of the ChatGPT teacher survey, Education and Information Technologies, pp. 1-37, (2024); Briner R. B., Denyer D., Systematic review and evidence synthesis as a practice and scholarship tool, Handbook of evidence-based management: companies, classrooms and research, pp. 112-129, (2012); Broadus R. N., Toward a definition of “bibliometrics”, Scientometrics, 12, 5–6, pp. 373-379, (1987); Chai C. S., Lin P. Y., Jong M. S. Y., Dai Y., Chiu T. K., Qin J., Perceptions of and behavioral intentions towards learning artificial intelligence in primary school students, Educational Technology & Society, 24, 3, pp. 89-101, (2021); Chatterjee S., Bhattacharjee K. K., Adoption of artificial intelligence in higher education: A quantitative analysis using structural equation modelling, Education and Information Technologies, 25, pp. 3443-3463, (2020); Chiu T. K. F., Xia Q., Zhou X., Chai C. S., Cheng M., Systematic literature review on opportunities, challenges, and future research recommendations of artificial intelligence in education, Computers and Education: Artificial Intelligence, 4, (2023); Chocarro R., Cortinas M., Marcos-Matas G., Teachers’ attitudes towards chatbots in education: a technology acceptance model approach considering the effect of social language, bot proactiveness, and users’ characteristics, Educational Studies, 49, 2, pp. 295-313, (2023); Chou C. Y., Chan T. W., Lin C. J., Redefining the learning companion: the past, present, and future of educational agents, Computers & Education, 40, 3, pp. 255-269, (2003); Cobo M. J., Lopez-Herrera A. G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: A practical application to the Fuzzy Sets Theory field, Journal of Informetrics, 5, 1, pp. 146-166, (2011); Cooper G., Examining science education in ChatGPT: An exploratory study of generative artificial intelligence, Journal of Science Education and Technology, 32, 3, pp. 444-452, (2023); Cotton D. R. E., Cotton P. A., Shipway J. R., Chatting and cheating: Ensuring academic integrity in the era of ChatGPT, Innovations in Education and Teaching International, 61, 2, pp. 228-239, (2023); Delgado H. O. K., de Azevedo Fay A., Sebastiany M. J., Silva A. D. C., Artificial intelligence adaptive learning tools: the teaching of English in focus, BELT-Brazilian English Language Teaching Journal, 11, 2, (2020); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Emin C., Kayri M., Dogan E., Examining the Influence of Narcissism and Some Demographic Variables on Online Shopping Addiction via the Exhaustive CHAID Method, International Journal of Mental Health and Addiction, pp. 1-17, (2024); Faria L., Silva A., Vale Z., Marques A., Training control centers' operators in incident diagnosis and power restoration using intelligent tutoring systems, IEEE Transactions on Learning Technologies, 2, 2, pp. 135-147, (2009); Farrokhnia M., Banihashem S. K., Noroozi O., Wals A., A SWOT analysis of ChatGPT: Implications for educational practice and research, Innovations in Education and Teaching International, 61, 3, pp. 460-474, (2023); Fyfe P., How to cheat on your final paper: Assigning AI for student writing, AI & Society, 38, 4, pp. 1395-1405, (2023); Garcia P., Amandi A., Schiaffino S., Campo M., Evaluating Bayesian networks’ precision for detecting students’ learning styles, Computers & Education, 49, 3, pp. 794-808, (2007); Goralski M. A., Tan T. K., Artificial intelligence and sustainable development, The International Journal of Management Education, 18, 1, (2020); Guo S., Zheng Y., Zhai X., Artificial intelligence in education research during 2013–2023: A review based on bibliometric analysis, Education and Information Technologies, pp. 1-23, (2024); Halff H. M., Instructional applications of artificial intelligence, Educational Leadership, 43, 6, pp. 24-31, (1986); Haque M. U., Dharmadasa I., Sworna Z. T., Rajapakse R. N., Ahmad H., "" I think this is the most disruptive technology"": Exploring Sentiments of ChatGPT Early Adopters using Twitter Data, (2022); Hinojo-Lucena F. J., Aznar-Diaz I., Caceres-Reche M. P., Romero-Rodriguez J. M., Artificial intelligence in higher education: A bibliometric study on its impact in the scientific literature, Education Sciences, 9, 1, (2019); Hwang G. J., A conceptual map model for developing intelligent tutoring systems, Computers & Education, 40, 3, pp. 217-235, (2003); Jeon J., Exploring AI chatbot affordances in the EFL classroom: Young learners’ experiences and perspectives, Computer Assisted Language Learning, 37, 1-2, pp. 1-26, (2024); Johnson W. B., Neste L. O., Duncan P. C., An authoring environment for intelligent tutoring systems, Conference Proceedings., IEEE International Conference on Systems, Man and Cybernetics, pp. 761-765, (1989); Kasneci E., Sessler K., Kuchemann S., Bannert M., Dementieva D., Fischer F., Gasser U., Groh G., Gunnemann S., Hullermeier E., Krusche S., Kutyniok G., Michaeli T., Nerdel C., Pfeffer J., Poquet O., Sailer M., Schmidt A., Seidel T., Kasneci G., ChatGPT for good? On opportunities and challenges of large language models for education, Learning and Individual Differences, 103, (2023); Kessler G., Technology and the future of language teaching, Foreign Language Annals, 51, 1, pp. 205-218, (2018); Kong S. C., Cheung W. M. Y., Zhang G., Evaluation of an artificial intelligence literacy course for university students with diverse study backgrounds, Computers and Education: Artificial Intelligence, 2, (2021); Lameras P., Sylvester A., Power to the Teachers: An Exploratory Review on Artificial Intelligence in Education, Information, 13, 1, (2022); Li L., Ma Z., Fan L., Lee S., Yu H., Hemphill L., ChatGPT in education: A discourse analysis of worries and concerns on social media, Education and Information Technologies, (2023); Lim W. M., Gunasekara A., Pallant J. L., Pallant J. I., Pechenkina E., Generative AI and the future of education: Ragnarök or reformation? A paradoxical perspective from management educators, The International Journal of Management Education, 21, 2, (2023); Lin Y., Yu Z., A bibliometric analysis of artificial intelligence chatbots in educational contexts, Interactive Technology and Smart Education, 21, 2, pp. 189-213, (2024); Liu S., Liu S., Liu Z., Peng X., Yang Z., Automated detection of emotional and cognitive engagement in MOOC discussions to predict learning achievement, Computers & Education, 181, (2022); Loeckx J., Blurring boundaries in education: Context and impact of MOOCs, International Review of Research in Open and Distributed Learning, 17, 3, pp. 92-121, (2016); Luckin R., Cukurova M., Kent C., du Boulay B., Empowering educators to be AI-ready, Computers and Education: Artificial Intelligence, 3, (2022); Mao G., Hu H., Liu X., Crittenden J., Huang N., A bibliometric analysis of industrial wastewater treatments from 1998 to 2019, Environmental Pollution, 275, (2021); McBurney M. K., Novak P. L., What is bibliometrics and why should you care?, Proceedings. IEEE international professional communication conference, pp. 108-114, (2002); Mitnik R., Recabarren M., Nussbaum M., Soto A., Collaborative robotic instruction: A graph teaching experience, Computers & Education, 53, 2, pp. 330-342, (2009); Moral-Munoz J. A., Herrera-Viedma E., Santisteban-Espejo A., Cobo M. J., Software tools for conducting bibliometric analysis in science: An up-to-date review, Profesional De La Información, 29, 1, (2020); ChatGPT: Optimizing language models for dialogue, (2023); Pradana M., Elisa H. P., Syarifuddin S., Discussing ChatGPT in education: A literature review and bibliometric analysis, Cogent Education, 10, 2, (2023); Qian K., Zhong Z., Research frontiers of electroporation-based applications in cancer treatment: A bibliometric analysis, Biomedical Engineering/Biomedizinische Technik, 68, 5, pp. 445-456, (2023); Qu J., Zhao Y., Xie Y., Artificial intelligence leads the reform of education models, Systems Research and Behavioral Science, 39, 3, pp. 581-588, (2022); Qu J., Zhao Y., Xie Y., Artificial intelligence leads the reform of education models, Systems Research and Behavioral Science, 39, 3, pp. 581-588, (2022); Scharth M., The ChatGPT chatbot is blowing people away with its writing skills, (2022); Seldon A., Abidoye O., The Fourth Education Revolution: Will Artificial Intelligence Liberate or Infantilise Humanity, (2018); Strzelecki A., To use or not to use ChatGPT in higher education? A study of students’ acceptance and use of technology, Interactive Learning Environments, pp. 1-14, (2023); Tang K. Y., Chang C. Y., Hwang G. J., Trends in artificial intelligence-supported e-learning: A Systematic review and co-citation network analysis (1998–2019), Interactive Learning Environments, pp. 1-19, (2021); Transformer G. G. P., Thunstrom A. O., Steingrimsson S., Can GPT-3 write an academic paper on itself, with minimal human input?, (2022); Tsai S. C., Chen C. H., Shiao Y. T., Ciou J. S., Wu T. N., Precision education with statistical learning and deep learning: a case study in Taiwan, International Journal of Educational Technology in Higher Education, 17, pp. 1-13, (2020); Preliminary Study on the Ethics of Artificial Intelligence, (2019); Vazquez-Cano E., Mengual-Andres S., Lopez-Meneses E., Chatbot to improve learning punctuation in Spanish and to enhance open and flexible learning environments, International Journal of Educational Technology in Higher Education, 18, pp. 1-20, (2021); Verma S., Gustafsson A., Investigating the emerging COVID-19 research trends in the field of business and management: A bibliometric analysis approach, Journal of Business Research, 118, pp. 253-261, (2020); Wang P., On defining artificial intelligence, Journal of Artificial General Intelligence, 10, 2, pp. 1-37, (2019); Wang S., Wang F., Zhu Z., Wang J., Tran T., Du Z., Artificial intelligence in education: A systematic literature review, Expert Systems with Applications, 252, (2024); Xu L. D., Lu Y., Li L., Embedding blockchain technology into IoT for security: A survey, IEEE Internet of Things Journal, 8, 13, pp. 10452-10473, (2021); Yan D., Impact of ChatGPT on learners in a L2 writing practicum: An exploratory investigation, Education and Information Technologies, 28, 11, pp. 13943-13967, (2023); Yang W., Artificial intelligence education for young children: Why, what, and how in curriculum design and implementation, Computers and Education: Artificial Intelligence, 3, (2022); Zawacki-Richter O., Marin V. I., Bond M., Gouverneur F., Systematic review of research on artificial intelligence applications in higher education–where are the educators?, International Journal of Educational Technology in Higher Education, 16, 1, pp. 1-27, (2019); Zhai X., Chu X., Chai C. S., Jong M. S. Y., Istenic A., Spector M., Li Y., A Review of Artificial Intelligence (AI) in Education from 2010 to 2020, Complexity, 2021, 1, (2021); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","E. Doğan; Measurement and Evaluation, Van Yüzüncü Yıl University, Van, Turkey; email: ezgidogan@yyu.edu.tr","","Ozgen Korkmaz","","","","","","21486123","","","","English","Particip. Educ. Res.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85217052455" -"Shahait M.; Ibrahim S.; Baqain L.; Abdul-Sater Z.","Shahait, Mohammed (55874977700); Ibrahim, Sarah (58278818400); Baqain, Laith (58530865200); Abdul-Sater, Zahi (55327045100)","55874977700; 58278818400; 58530865200; 55327045100","Bibliometric analysis of focal therapy in prostate cancer research","2024","BJUI Compass","5","6","","602","609","7","1","10.1002/bco2.353","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85188470662&doi=10.1002%2fbco2.353&partnerID=40&md5=23c0c6eff58faf80058050f25927849e","Department of Surgery, Clemenceau Medical Center, Dubai, United Arab Emirates; Global Health Institute, American University of Beirut, Beirut, Lebanon; Faculty of Medicine, University of Jordan, Amman, Jordan; College of Public Health, Phoenicia University, Mazraat El Daoudiyeh, Lebanon","Shahait M., Department of Surgery, Clemenceau Medical Center, Dubai, United Arab Emirates; Ibrahim S., Global Health Institute, American University of Beirut, Beirut, Lebanon; Baqain L., Faculty of Medicine, University of Jordan, Amman, Jordan; Abdul-Sater Z., College of Public Health, Phoenicia University, Mazraat El Daoudiyeh, Lebanon","Introduction: The use of focal therapies for prostate cancer (PCa) has soared, as it controls disease and is associated with minimal side effects. Bibliometric analysis examines the global research landscape on any topic to identify gaps in the research and areas for improvement and prioritize future research efforts. This study aims to examine the research outputs and trends and collaboration landscape in the field of focal therapy for PCa on a global scale. Methods: We searched Medline, PubMed and Scopus for peer-reviewed publications on our research topic using controlled keywords. Search results were limited to the period between 1980 and 2022, screened for duplicates and then included in our study based on prespecified eligibility criteria. The Bibliometrix Package was used for comprehensive science mapping analysis of co-authorship, co-citation and co-occurrence analysis of countries, institutions, authors, references and keywords in this field. Results: This analysis included 2578 research articles. The annual scientific production increased from one article in 1982 to 143 in 2022 (13.21%). The average citation per year was incrementally increasing, and these documents were cited around 32.52 times. The documents included in this analysis were published in 633 sources. The international collaboration index was 22.7. In total, 6280 author keywords were identified. The most used keywords were ‘prostate cancer’, ‘focal therapy’, ‘prostate’ and ‘photodynamic therapy’. Conclusion: This bibliometric analysis has provided a comprehensive review of focal therapy in PCa research, highlighting both the significant growth in the field and the existing gaps that require further exploration. The study points to the need for more diverse international collaboration and exploration of various treatment modalities within the context of focal therapy. © 2024 The Authors. BJUI Compass published by John Wiley & Sons Ltd on behalf of BJU International Company.","bibliometric; focal therapy; prostate cancer","","","","","","","","Ma C., Su H., Li H., Global research trends on prostate diseases and erectile dysfunction: a bibliometric and visualized study, Front Oncol, 10, (2021); Siegel R.L., Miller K.D., Jemal A., Cancer statistics, 2018, CA Cancer J Clin, 68, 1, pp. 7-30, (2018); Sanda M.G., Cadeddu J.A., Kirkby E., Chen R.C., Crispino T., Fontanarosa J., Et al., Clinically localized prostate cancer: AUA/ASTRO/SUO guideline. Part I: risk stratification, shared decision making, and care options, J Urol, 199, 3, pp. 683-690, (2018); Thompson I.M., Overdiagnosis and overtreatment of prostate cancer, Am Soc Clin Oncol Educ Book, pp. e35-e39, (2012); Kinsella N., Helleman J., Bruinsma S., Carlsson S., Cahill D., Brown C., Et al., Active surveillance for prostate cancer: a systematic review of contemporary worldwide practices, Transl Androl Urol, 7, 1, pp. 83-97, (2018); Venderbos L.D., van den Bergh R.C.N., Roobol M.J., Schroder F.H., Essink-Bot M.L., Bangma C.H., Et al., A longitudinal study on the impact of active surveillance for prostate cancer on anxiety and distress levels, Psychooncology, 24, 3, pp. 348-354, (2015); Ong S., Chen K., Grummet J., Yaxley J., Scheltema M.J., Stricker P., Et al., Guidelines of guidelines: focal therapy for prostate cancer, is it time for consensus?, BJU Int, 131, 1, pp. 20-31, (2023); Chadegani A.A., Salehi H., Yunus M.M., Farhadi H., Fooladi M., Farhadi M., Ebrahim N.A., A comparison between two main academic literature collections: Web of Science and Scopus databases, (2013); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, J Informet, 11, 4, pp. 959-975, (2017); Hirsch J.E., An index to quantify an individual's scientific research output, Proc Natl Acad Sci U S a, 102, 46, pp. 16569-16572, (2005); Uthman O.A., Okwundu C.I., Wiysonge C.S., Young T., Clarke A., Citation classics in systematic reviews and meta-analyses: who wrote the top 100 most cited articles?, PLoS ONE, 8, 10, (2013); Vaudano E., Research collaborations and quality in research: foes or friends?, Good research practice in non-clinical pharmacology and biomedicine, pp. 383-398, (2020); Awada H., Ali A.H., Zeineddine M.A., Nassereldine H., Abdul Sater Z., Mukherji D., The status of bladder cancer research worldwide, a bibliometric review and recommendations, Arab J Urol, 21, 1, pp. 1-9, (2023); Eckhouse S., Lewison G., Sullivan R., Trends in the global funding and activity of cancer research, Mol Oncol, 2, 1, pp. 20-32, (2008); Wang J., Shapira P., Wray K.B., Is there a relationship between research sponsorship and publication impact? An analysis of funding acknowledgments in nanotechnology papers, PLoS ONE, 10, 2, (2015); Nassereldine H., Awada H., Ali A.H., Zeineddine M., Sater Z.A., Shaib Y., Pancreatic cancer in the MENA region, a bibliometric review; el Rassi R., Meho L.I., Nahlawi A., Salameh J.S., Bazarbachi A., Akl E.A., Medical research productivity in the Arab countries: 2007–2016 bibliometric analysis, J Glob Health, 8, 2, (2018); Latif R., Medical and biomedical research productivity from the Kingdom of Saudi Arabia (2008–2012), J Fam Community Med, 22, 1, pp. 25-30, (2015); List of Institutions Funding Cancer Research, (2019); Hilal L., Shahait M., Mukherji D., Charafeddine M., Farhat Z., Temraz S., Et al., Prostate cancer in the Arab world: a view from the inside, Clin Genitourin Cancer, 13, 6, pp. 505-511, (2015)","Z. Abdul-Sater; Phoenicia University, Mazraat El Daoudiyeh, Lebanon; email: zahi.abdulsater@pu.edu.lb","","John Wiley and Sons Inc","","","","","","26884526","","","","English","BJUI Compass","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85188470662" -"Talawar A.; Sheena S.; Alathur S.","Talawar, Abhishek (58958601200); Sheena, Suresh (59172317000); Alathur, Sreejith (54882419700)","58958601200; 59172317000; 54882419700","Recent Technological Developments in the Tourism Industry: A Bibliometric Analysis","2024","Lecture Notes in Networks and Systems","908","","","283","298","15","0","10.1007/978-981-97-0210-7_23","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192363458&doi=10.1007%2f978-981-97-0210-7_23&partnerID=40&md5=0c62a02649226eb810ff2ecfa5d7a3c0","School of Humanities, Social Sciences and Management, National Institute of Technology Karnataka, Mangaluru, India; Information Systems, Indian Institute of Management Kozhikode, Kunnamangalam, India","Talawar A., School of Humanities, Social Sciences and Management, National Institute of Technology Karnataka, Mangaluru, India; Sheena S., School of Humanities, Social Sciences and Management, National Institute of Technology Karnataka, Mangaluru, India; Alathur S., Information Systems, Indian Institute of Management Kozhikode, Kunnamangalam, India","The tourism industry has witnessed substantial technological advancements in recent years because of the rapid growth of information and communication technologies (ICT). Previous literature indicates that most of the research has been focused on comprehending the application of various technologies in the tourism sector and their impact on consumer behavior. However, no bibliometric studies are undertaken to analyze the relevant publications, the effect of technology and the emerging trends in technology within the tourism industry. This study aims to conduct a bibliometric analysis to explore and evaluate these developments. Therefore, the study performed a bibliometric analysis of 1430 published research articles from the Scopus database for the period 2018–2022. The bibliometric analysis involved a performance analysis and science mapping of the publications using the Bibliometrix R package software. The results indicate an increasing trend in publications and the year 2022 recorded the highest number of articles published. The study found that Law R., Buhalis D., and Gretzel were the most productive authors in the last five years. Moreover, the analysis showed that the top ten journals accounted for one-third of the total publications. The conceptual structure indicated that the well-developed topics are represented by keywords such as innovation, Covid-19, tourism development, and destinations. Furthermore, the intellectual structure revealed three unique clusters indicating the theoretical foundations within tourism research, smart tourism and value co-creation in tourism. Finally, this study will benefit academicians and tourism marketers to gain insights into technological advancements and emerging trends in tourism research. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024.","Bibliometric analysis; Bibliometrix; Technology; Tourism; Tourism development","Publishing; Tourism; Bibliometrics analysis; Bibliometrix; Emerging trends; Information and Communication Technologies; Rapid growth; Technological advancement; Technological development; Technology; Tourism development; Tourism industry; Consumer behavior","","","","","","","Leiper N., An etymology of “tourism, Ann Tour Res, 10, 83, pp. 90033-90036, (1983); Maric I., Obadic A., The Significance of Tourism as an Employment Generator of Female Labour Force. Significance Tour. as an Employ Gener Female Labour Force 18, (2009); Roziqin A., Kurniawan A.S., Hijri Y.S., Kismartini K., Research Trends of Digital Tourism: A Bibliometric Analysis, (2023); Digital Transformation Monitor: Augmented and Virtual Reality, (2017); Tom Dieck D., Tom Dieck M.C., Jung T., Moorhouse N., Tourists’ virtual reality adoption: An exploratory study from Lake District National Park, Leis Stud, 37, (2018); Huang T.-L., Liu B.S.C., Augmented Reality is Human-Like: How the Humanizing Experience Inspires Destination Brand Love, (2021); Bigne E., Maturana P., Does virtual reality trigger visits and booking holiday travel packages?, Cornell Hosp Q, (2022); Kim H.W., Chan H.C., Gupta S., Value-based adoption of mobile internet: An empirical investigation, Decis Support Syst, 43, (2007); Rahimizhian S., Ozturen A., Ilkan M., Emerging realm of 360-degree technology to promote tourism destination, Technol Soc, 63, (2020); Guttentag D.A., Virtual reality: Applications and implications for tourism, Tour Manage, 31, pp. 637-651, (2010); 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Gretzel U., Sigala M., Xiang Z., Koo C., Smart tourism: Foundations and developments, Electron Mark, 25, (2015); Buhalis D., Foerste M., SoCoMo marketing for travel and tourism: Empowering cocreation of value, J Destin Mark Manage, 4, (2015); Wang D., Xiang Z., Fesenmaier D.R., Smartphone use in everyday life and travel, J Travel Res, 55, (2016); Buhalis D., Sinarta Y., Real-time co-creation and nowness service: lessons from tourism and hospitality, J Travel Tour Mark, 36, (2019)","A. Talawar; School of Humanities, Social Sciences and Management, National Institute of Technology Karnataka, Mangaluru, India; email: abhi6506@gmail.com","Joshi A.; Mahmud M.; Ragel R.G.; Kartik S.","Springer Science and Business Media Deutschland GmbH","","8th International Conference on Information and Communication Technology for Competitive Strategies, ICTCS 2023","8 December 2023 through 9 December 2023","Jaipur","309709","23673370","978-981970209-1","","","English","Lect. Notes Networks Syst.","Conference paper","Final","","Scopus","2-s2.0-85192363458" -"Dekhnich O.V.; Litvinova T.A.","Dekhnich, Olga V. (56436702200); Litvinova, Tatyana A. (56638057700)","56436702200; 56638057700","A keystroke analysis to study writing: a bibliometric review using R and VOSviewer; [Анализ клавиатурного почерка в исследованиях письма: библиометрический обзор с использованием инструментов R и VOSviewer]","2024","Research Result. Theoretical and Applied Linguistics","10","3","","91","115","24","0","10.18413/2313-8912-2024-10-3-0-5","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85208605351&doi=10.18413%2f2313-8912-2024-10-3-0-5&partnerID=40&md5=d547f62b27d544e7db8a3414530406dc","Belgorod State National Research University, 85 Pobedy St., Belgorod, 308015, Russian Federation; Voronezh State Pedagogical University, 86 Lenin St., Voronezh, 394043, Russian Federation","Dekhnich O.V., Belgorod State National Research University, 85 Pobedy St., Belgorod, 308015, Russian Federation; Litvinova T.A., Voronezh State Pedagogical University, 86 Lenin St., Voronezh, 394043, Russian Federation","Data obtained by means of keystroke logging software, which records all writing events, i.e., all keypresses with their time stamps, are widely used in different research fields and practical applications – from early detection of cognitive impairments to user authentication. Keystroke logging software have become especially popular in writing studies since it allows researchers to observe writing processes unobtrusively and increases their understanding of what happens “behind the scenes” of text production. This methodology has been used in writing studies since the advent of affordable computers in the 1990s, however, there has still been no bibliometric review that would provide a holistic picture of this field and identify hot topics and trends, perform citation analysis and identify the most productive authors and countries in the field of writing research using keystroke data. This paper is pioneer research to conducting a bibliometric analysis on the field “keystroke analysis to study writing” aimed at filling in the gap. A search was conducted in the bibliographic database Scopus on July 11, 2024. We included studies published in English post-2000 that discuss the use of keystroke data and methodology to study writing process. This review followed the guidelines of the PRISMA protocol to perform the study search and selection. The search yielded 336 documents of which 273 met out inclusion criteria. The records retrieved were analysed using the bibliometrix R-package and VOSviewer software. Using these tools in combinations, we implemented both performance analysis which examines the contributions of research constituents to a given field and science mapping which is aimed at revealing the relationships between research constituents. The contribution of this study is twofold. Firstly, it provides an in-depth bibliometric analysis of an actively developing field of research which is rather limited in terms osf the countries and institutions involved (and the languages of the texts analysed), hopefully saving time and effort for researchers new to the field. Secondly, we provide an example of using bibliometrix and VOSviewer for a bibliometric analysis which could be easily replicated in further research. © 2024 Belgorod State National Research University. All rights reserved.","Bibliometric review; bibliometrix R-package; Citation analysis; Conceptual structure; Keystroke dynamics; Keyword co-occurrence; PRISMA protocol; Scopus database; Thematic evolution; VOSviewer; Writing research; Writing studies","","","","","","Ministry of Education and Science of the Russian Federation, Minobrnauka, (QRPK-2024-0011)","Acknowledgements: Tatiana A. Litvinova acknowledges the support of the Ministry of Education of the Russian Federation (the research was supported by the Ministry of Education of the Russian Federation within the framework of the state task in the field of science, topic number QRPK-2024-0011). Olga V. Dekhnich received no financial support for the research, authorship, and publication of this article.","Alfalahi H., Khandoker A. H., Chowdhury N., Iakovakis D., Dias S. B., Chaudhuri K. R., Hadjileontiadis L. J., Diagnostic accuracy of keystroke dynamics as digital biomarkers for fine motor decline in neuropsychiatric disorders: a systematic review and meta-analysis, Sci Rep, 12, (2022); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bixler R., D'Mello S., Detecting boredom and engagement during writing with keystroke analysis, task appraisals, and stable traits, Proceedings of the 2013 International conference on Intelligent user interfaces (IUI ‘13), pp. 225-234, (2013); Buyukkidik S., A bibliometric analysis: A tutorial for the bibliometrix package in R using IRT literature, Journal of Measurement and Evaluation in Education and Psychology, 13, 3, pp. 164-193, (2022); Cui Y., Mou J., Liu Y., Knowledge mapping of social commerce research: A visual analysis using CiteSpace, Electronic Commerce Research, 18, 4, pp. 837-868, (2018); Dervis H., Bibliometric analysis using bibliometrix an R package, Journal of Scientometric Research, 8, 3, pp. 156-160, (2019); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Farrukh M., Raza A., Mansoor A., Khan M. S., Lee J. W. C., Trends and patterns in pro-environmental behaviour research: a bibliometric review and research agenda, Benchmarking: an International Journal, 30, 3, pp. 681-696, (2023); Lee S. A., Park J. H., Do Individuals with Mild Cognitive Impairment and Healthy Aging People Have Different Keystroke Dynamics? A Systematic Review, International Journal of Gerontology, 18, 2, pp. 64-69, (2024); Leijten M., Van Waes L., Keystroke logging in writing research: Using inputlog to analyze and visualize writing processes, Written Communication, 30, 3, pp. 358-392, (2013); Leijten M., Van Waes L., Schriver K., Hayes J. R., Writing in the workplace: Constructing documents using multiple digital sources, Journal of Writing Research, 5, 3, pp. 285-337, (2013); Logan G. D., Crump M. J., Cognitive illusions of authorship reveal hierarchical error detection in skilled typists, Science, 330, 6004, pp. 683-686, (2010); Maalej A., Kallel I., Does Keystroke Dynamics tell us about Emotions? A Systematic Literature Review and Dataset Construction, 2020 16th International Conference on Intelligent Environments (IE), pp. 60-67, (2020); Nguyen T. M., Leow A. D., Ajilore O., A Review on Smartphone Keystroke Dynamics as a Digital Biomarker for Understanding Neurocognitive Functioning, Brain Sci, 13, (2023); Omotehinwa T. O., Examining the developments in scheduling algorithms research: a bibliometric approach, Heliyon, 8, 5, (2022); Passas I., Bibliometric Analysis: The Main Steps, Encyclopedia, 4, pp. 1014-1025, (2024); Quraishi S. J., Bedi S. S., Keystroke Dynamics Biometrics, A tool for User Authentication – Review, 2018 International Conference on System Modeling & Advancement in Research Trends (SMART), pp. 248-254, (2018); Rashid M. F. A., How to Conduct a Bibliometric Analysis using R Packages: A Comprehensive Guidelines, Journal of Tourism, Hospitality & Culinary Arts, 15, 1, pp. 24-39, (2023); Raul N., Shankarmani R., Joshi P., A Comprehensive Review of Keystroke Dynamics-Based Authentication Mechanism, International Conference on Innovative Computing and Communications. Advances in Intelligent Systems and Computing, 1059, (2020); Rejeb A., Rejeb K., Appolloni A., Kayikci Y., Iranmanesh M., The landscape of public procurement research: a bibliometric analysis and topic modelling based on Scopus, Journal of Public Procurement, 23, 2, pp. 145-178, (2023); Saini G. K., Lievens F., Srivastava M., Employer and internal branding research: a bibliometric analysis of 25 years, Journal of Product & Brand Management, 31, 8, pp. 1196-1221, (2022); Small H., Co-citation in the scientific literature: a new measure of the relationship between two documents, J Am Soc Inf Sci, 24, pp. 265-269, (1973); Stevenson M., Schoonen R., Glopper K., Revising in two languages: A multi-dimensional comparison of online writing revisions in L1 and FL, Journal of Second Language Writing, 15, 3, pp. 201-233, (2006); Tikhonova E., Kosycheva M., Kasatkin P., Exploring Academic Culture: Unpacking its Definition and Structure (a Systematic Scoping Review), Journal of Language and Education, 9, 36, pp. 151-168, (2023); Van Eck N. J., Waltman L., Visualizing bibliometric networks, Measuring scholarly impact: Methods and practice, pp. 285-320, (2014); Wang S., Gu Z., Mapping the Field of Value Chain: A Bibliometric and Visualization Analysis, Sustainability, 14, (2022); Wengelin A., Examining Pauses in Writing: Theory, Methods and Empirical Data, Computer Keystroke Logging and Writing: Methods and Applications, (2006); Wengelin A., Johansson V., Investigating Writing Processes with Keystroke Logging, Digital Writing Technologies in Higher Education, (2023); Yang L., Qin S.-F., A Review of Emotion Recognition Methods From Keystroke, Mouse, and Touchscreen Dynamics, IEEE Access, 9, pp. 162197-162213, (2021)","","","Belgorod State National Research University","","","","","","23138912","","","","English","Res. Result. Theor. Appl. Linguist.","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85208605351" -"Musova Z.; Musa H.; Rech F.","Musova, Zdenka (57193669273); Musa, Hussam (57189098824); Rech, Frederik (57209581336)","57193669273; 57189098824; 57209581336","Circular economy challenges: a bibliometric exploration of cognitive and behavioral barriers","2025","Journal of Organizational Change Management","","","","","","","0","10.1108/JOCM-01-2025-0011","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105004833749&doi=10.1108%2fJOCM-01-2025-0011&partnerID=40&md5=f972faa78bbfad1669c4baecb073bb92","Department of Corporate Economics and Management, Matej Bel University in Banska Bystrica, Banska Bystrica, Slovakia; Department of Finance and Accounting, Matej Bel University in Banska Bystrica, Banska Bystrica, Slovakia; School of Economics, Beijing Institute of Technology, Beijing, China","Musova Z., Department of Corporate Economics and Management, Matej Bel University in Banska Bystrica, Banska Bystrica, Slovakia; Musa H., Department of Finance and Accounting, Matej Bel University in Banska Bystrica, Banska Bystrica, Slovakia; Rech F., School of Economics, Beijing Institute of Technology, Beijing, China","Purpose: Despite its growing prominence, the adoption and implementation of circular economy practices remain hindered by a range of systemic, institutional, cognitive and behavioral barriers. While technical and economic challenges have received significant attention, the cognitive and psychological dimensions of these barriers are still underexplored. The paper aims to analyze the current trends and set the future research agenda for multidisciplinary research on the intersection of circular economy and cognitive and behavioral barriers. Design/methodology/approach: Bibliographic data on cognitive and behavioral barriers in circular economy practices were extracted from the SCOPUS database and analyzed using VOSviewer software for visualization and Bibliometrix R for performance analysis. Findings: This paper analyzes 814 multidisciplinary publications on cognitive and behavioral barriers in circular economy practices from 1983 to 2023. For this, the paper identifies key research themes, influential authors, journals and trends in literature. Also, the paper visualizes the mapping of the co-occurrence of keywords and author collaboration networks. Despite examining the intersection of circular economy and behavioral barriers, the co-occurrence analysis highlights a persistent gap in fully integrating these two fields, emphasizing the need for more interdisciplinary research. Originality/value: The paper provides a holistic view of trends and future research directions for multidisciplinary research on the intersection of circular economy and cognitive and behavioral barriers, based on performance analysis and science mapping, offering a unique contribution to the literature. © 2025, Emerald Publishing Limited.","Behavioral barrier; Bibliometric analysis; Circular economy; Cognitive barriers; Scopus","","","","","","Vedecká Grantová Agentúra MŠVVaŠ SR a SAV, VEGA, (APVV-23–0018, 1/0479/23, 1/0120/25); Vedecká Grantová Agentúra MŠVVaŠ SR a SAV, VEGA","This paper has been supported by the Scientific Grant Agency of Slovak Republic under contract No. APVV-23\u20130018 and project VEGA No. 1/0479/23 \u201CResearch of circular consumer behavior in the context of STP marketing model\u201D, and VEGA No. 1/0120/25 \u201CResearch of paradigms and determinants of management processes and ESG implementation in the context of the required financial performance of companies and changes resulting from the CSRD directive\u201D. The authors would like to express their gratitude to the Scientific Grant Agency of The Ministry of Education, Research, Development and Youth of the Slovak Republic for financial support of this research and publication. 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A scoping review, Journal of Health, Organisation and Management, 35, 3, pp. 344-381, (2020); Paul J., Khatri P., Kaur Duggal H., Frameworks for developing impactful systematic literature reviews and theory building: what, why and how?, Journal of Decision Systems, 33, 4, pp. 537-550, (2023); Pienwisetkaew T., Wongsaichia S., Pinyosap B., Prasertsil S., Poonsakpaisarn K., Ketkaew C., The behavioral intention to adopt circular economy-based digital technology for agricultural waste valorization, Foods, 12, 12, (2023); Post C., Sarala R., Gatrell C., Prescott J.E., Advancing theory with review articles, Journal of Management Studies, 57, 2, pp. 351-376, (2020); Prothero A., Dobscha S., Freund J., Kilbourne W.E., Luchs M.G., Ozanne L.K., Thogersen J., Sustainable consumption: opportunities for consumer research and public policy, Journal of Public Policy and Marketing, 30, 1, pp. 31-38, (2011); R Core Team 2023 R: A Language and Environment for Statistical Computing, (2023); Ranta V., Aarikka-Stenroos L., Ritala P., Makinen S.J., Exploring institutional drivers and barriers of the circular economy: a cross-regional comparison of China, the US, and Europe, Resources, Conservation and Recycling, 135, pp. 70-82, (2018); Sabbir M.M., Taufique K.M.R., Nomi M., Consumers’ reverse exchange behavior and e-waste recycling to promote sustainable post-consumption behavior, Asia Pacific Journal of Marketing and Logistics, 35, 10, pp. 2484-2500, (2023); Santeramo F.G., Circular and green economy: the state-of-the-art, Heliyon, 8, 4, (2022); Santibanez Gonzalez E.D.R., Kandpal V., Machado M., Martens M.L., Majumdar S., A bibliometric analysis of circular economies through sustainable smart cities, Sustainability (Switzerland), 15, 22, (2023); Senadheera S.S., Gregory R., Rinklebe J., Farrukh M., Rhee J.H., Ok Y.S., The development of research on environmental, social, and governance (ESG): a bibliometric analysis, Sustainable Environment, 8, 1, (2022); Sotamenou J., De Jaeger S., Rousseau S., Drivers of legal and illegal solid waste disposal in the Global South - the case of households in Yaoundé (Cameroon), Journal of Environmental Management, 240, pp. 321-330, (2019); Sousa-Zomer T.T., Magalhaes L., Zancul E., Campos L.M.S., Cauchick-Miguel P.A., Cleaner production as an antecedent for circular economy paradigm shift at the micro-level: evidence from a home appliance manufacturer, Journal of Cleaner Production, 185, pp. 740-748, (2018); Tankard M.E., Paluck E.L., Norm perception as a Vehicle for social change, Social Issues and Policy Review, 10, 1, pp. 181-211, (2016); Van Eck N.J., Waltman L., How to normalize cooccurrence data? An analysis of some well-known similarity measures, Journal of the American Society for Information Science and Technology, 60, 8, pp. 1635-1651, (2009); Varju V., Ovari A., Mezei C., Suvak A., Ver C., Efforts and barriers shifting a city region towards circular transition – lessons from a living lab from Pécs, Hungary, Future Cities and Environment, 8, 1, (2022); Varotto A., Spagnolli A., Psychological strategies to promote household recycling. A systematic review with meta-analysis of validated field interventions, Journal of Environmental Psychology, 51, pp. 168-188, (2017); White K., Habib R., Hardisty D.J., How to SHIFT consumer behaviors to be more sustainable: a literature review and guiding framework, Journal of Marketing, 83, 3, pp. 22-49, (2019); Xiao C., Hong D., Gender differences in environmental behaviors among the Chinese public: model of mediation and moderation, Environment and Behavior, 50, 9, pp. 975-996, (2018); Yin S., Jia F., Chen L., Wang Q., Circular economy practices and sustainable performance: a meta-analysis, Resources, Conservation and Recycling, 190, (2023); Yuriev A., Dahmen M., Paille P., Boiral O., Guillaumie L., Pro-environmental behaviors through the lens of the theory of planned behavior: a scoping review, Resources, Conservation and Recycling, 155, (2020)","F. Rech; School of Economics, Beijing Institute of Technology, Beijing, China; email: frederikrech@gmail.com","","Emerald Publishing","","","","","","09534814","","","","English","J. Organ. Change Manage.","Article","Article in press","","Scopus","2-s2.0-105004833749" -"Kaya A.; Tuzcu A.","Kaya, Ayla (57195068978); Tuzcu, Ayla (56375271700)","57195068978; 56375271700","A Bibliometric Analysis of the 36-Year History of Cancer Nursing (1987-2023)","2024","Cancer Nursing","47","4","","252","260","8","1","10.1097/NCC.0000000000001324","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196731461&doi=10.1097%2fNCC.0000000000001324&partnerID=40&md5=aabea236af4e7b5804cb7fd4a28a0933","Department of Pediatric Nursing, Antalya, Turkey; Department of Public Health Nursing, Faculty of Nursing, Akdeniz University, Antalya, Turkey","Kaya A., Department of Pediatric Nursing, Antalya, Turkey; Tuzcu A., Department of Public Health Nursing, Faculty of Nursing, Akdeniz University, Antalya, Turkey","Background: Bibliometric analysis is an effective method for evaluating the publication characteristics and development of a journal. To our knowledge, this study is the first such analysis of the publications in Cancer Nursing. Objective: This study aimed to analyze the publication characteristics and evolution of Cancer Nursing over a period of 36 years since its inception. Methods: Bibliometric analysis was carried out on 3095 publications. Data were collected from the Web of Science Core Collection database on September 15, 2023. Data analysis was conducted with Web of Science Core Collection, VOSviewer, and Bibliometrix package in R software. Results: The results showed a steady increase in the citation and publication structure of Cancer Nursing. “Quality of life” was at the center of the studies, and “quality of life,” “women,” and “breast cancer” were identified as trend topics. The United States was both at the center of the cooperation network and was the country that contributed the most publications to the journal. Conclusion: Cancer Nursing has had an increasing contribution to and impact on cancer nursing in terms of the quality and citations of published articles. It was noted that the journal's network of collaboration has expanded globally and that its thematic diversity is high. Although quality of life, women, and breast cancer have been reported extensively, more studies addressing the concepts of “children,” “support,” and “needs” are needed in the journal. Implications for Practice: This study not only enriches global readers in the field of cancer nursing but may also be beneficial in providing input to guide future research. © 2024 Lippincott Williams and Wilkins. All rights reserved.","Bibliometric analysis; Cancer nursing; Nursing; Science mapping; Web of Science","Bibliometrics; History, 20th Century; History, 21st Century; Humans; Oncology Nursing; access to information; Article; bibliometrics; breast cancer; cancer chemotherapy; cancer palliative therapy; cancer screening; clinical assessment; clinical decision making; clinical evaluation; cooperation; data analysis; data base; early diagnosis; fatigue; human; information processing; malignant neoplasm; medical history; network analysis; oncology nursing; publication; qualitative research; quality of life; randomized controlled trial (topic); social support; software; systematic review; United States; Web of Science; history","","","","","Cancer Nursing Editorial Board","The authors would like to thank the Cancer Nursing Editorial Board, the journal team, and the authors who contributed data to this bibliometric analysis.","SJR: SCImago journal & country rank, (2022); Rachel A., Carol R.A., A message from the editors, (1978); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, J Bus Res, 133, pp. 285-296, (2021); Pritchard A., Statistical bibliography or bibliometrics, J Doc, 25, 4, pp. 348-349, (1969); Pritchard A., Bibliometrics and information transfer, Res Librariansh, 4, pp. 37-46, (1972); Choudhri A.F., Siddiqui A., Khan N.R., Cohen H.L., Understanding bibliometric parameters and analysis, Radiographics, 35, 3, pp. 736-746, (2015); Dubner R., A bibliometric analysis of the Pain journal as a representation of progress and trends in the field, Pain, 142, 1-2, pp. 9-10, (2009); Fischer J.P., Wininger A.E., Scofield D.C., Et al., Historical analysis of bibliometric trends in the Journal of Pediatric Orthopaedics with a particular focus on sex, J Pediatr Orthop, 38, 3, pp. e168-e171, (2018); Cunill M.O., Salva S.A., Gonzalez O.L., Mulet-Forteza C., Thirty-fifth anniversary of the International Journal of Hospitality Management: a bibliometric overview, Int J Hosp Manag, 78, pp. 89-101, (2019); Yanbing S., Ruifang Z., Chen W., Shifan H., Hua L., Zhiguang D., Bibliometric analysis of Journal of Nursing Management from 1993 to 2018, J Nurs Manag, 28, 2, pp. 317-331, (2020); Zeleznik D., Vosner B.H., Kokol P., A bibliometric analysis of the Journal of Advanced Nursing, 1976-2015, J Adv Nurs, 73, 10, pp. 2407-2419, (2017); Merigo J.M., Mas-Tur A., Roig-Tierno N., Ribeiro-Soriano D., A bibliometric overview of the Journal of Business Research between 1973 and 2014, J Bus Res, 68, 12, pp. 2645-2653, (2015); Verma S., Gustafsson A., Investigating the emerging COVID-19 research trends in the field of business and management: a bibliometric analysis approach, J Bus Res, 118, pp. 253-261, (2020); Zhu J., Liu W., A tale of two databases: the use of Web of Science and Scopus in academic papers, Scientometrics, 123, 1, pp. 321-335, (2020); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Kim H.J., McGuire D.B., Tulman L., Barsevick A.M., Symptom clusters: concept analysis and clinical implications for cancer nursing, Cancer Nurs, 28, 4, pp. 270-282, (2005); Dhawan S., Andrews R., Kumar L., Wadhwa S., Shukla G., A randomized controlled trial to assess the effectiveness of muscle strengthening and balancing exercises on chemotherapy-induced peripheral neuropathic pain and quality of life among cancer patients, Cancer Nurs, 43, 4, pp. 269-280, (2020); Han C.J., Yang G.S., Syrjala K., Symptom experiences in colorectal cancer survivors after cancer treatments: a systematic review and meta-analysis, Cancer Nurs, 43, 3, pp. 132-158, (2020); Newman M.E., Coauthorship networks and patterns of scientific collaboration, Proc Natl Acad Sci U S A, 101, pp. 5200-5205, (2004); Acedo F.J., Barroso C., Casanueva C., Galan J.L., Co-authorship in management and organizational studies: an empirical and network analysis, J Manag Stud, 43, 5, pp. 957-983, (2006); Keller K.G., Toriola A.T., Schneider J.K., The relationship between cancer fatalism and education, Cancer Causes Control, 32, 2, pp. 109-118, (2021); Kim H.K., Lwin M.O., Cultural determinants of cancer fatalism and cancer prevention behaviors among Asians in Singapore, Health Commun, 36, 8, pp. 940-949, (2021); Goh Y.S., Yong O.Q.Y.J., Chen T.H., Ho S.H.C., Chee Y.I.C., Chee T.T., The impact of COVID-19 on nurses working in a university health system in Singapore: a qualitative descriptive study, Int J Ment Health Nurs, 30, 3, pp. 643-652, (2021); Manguy A.M., Joubert L., Oakley E., Gordon R., Psychosocial care models for families of critically ill children in pediatric emergency department settings: a scoping review, J Pediatr Nurs, 38, pp. 46-52, (2018); Clarke N., Kearney P.M., Gallagher P., McNamara D., O'Morain C.A., Sharp L., Negative emotions and cancer fatalism are independently associated with uptake of faecal immunochemical test-based colorectal cancer screening: results from a population-based study, Prev Med (Baltim), 145, (2021); Paice J.A., Cohen F.L., Validity of a verbally administered numeric rating scale to measure cancer pain intensity, Cancer Nurs, 20, 2, pp. 88-93, (1997); Jacox A., Carr D.B., Payne R., Berde C.B., Management of Cancer Pain, (1994); World Migration Report, (2020); Chinese immigrants in the United States; Bottomley A., Reijneveld J.C., Koller M., Et al., Current state of quality of life and patient-reported outcomes research, Eur J Cancer, 121, pp. 55-63, (2019); Calvo-Schimmel A., Paul S.M., Cooper B.A., Et al., Oncology outpatients with worse anxiety and sleep disturbance profiles are at increased risk for a higher symptom burden and poorer quality of life, Cancer Nurs, 46, 6, pp. 417-431, (2023); El-Hussein A., Manoto S.L., Ombinda-Lemboumba S., Alrowaili Z.A., Mthunzi-Kufa P., A review of chemotherapy and photodynamic therapy for lung cancer treatment, Anticancer Agents Med Chem, 21, 2, pp. 149-161, (2020); Stephanos K., Dubbs S.B., Pediatric hematologic and oncologic emergencies, Emerg Med Clin, 39, 3, pp. 555-571, (2021)","A. Tuzcu; Department of Public Health Nursing, Faculty of Nursing, Akdeniz University, Antalya, Dumlupinar Blvd, 07058, Turkey; email: aylatuzcu@hotmail.com","","Lippincott Williams and Wilkins","","","","","","0162220X","","CANUE","38335453","English","Cancer Nurs.","Article","Final","","Scopus","2-s2.0-85196731461" -"Che Ibrahim C.K.I.; Ahmad Kamal N.","Che Ibrahim, Che Khairil Izam (57388434300); Ahmad Kamal, Norashikin (56545332900)","57388434300; 56545332900","A bibliometric exploration of accreditation in civil engineering education: trends and insights","2025","Quality Assurance in Education","","","","","","","0","10.1108/QAE-12-2024-0271","https://www.scopus.com/inward/record.uri?eid=2-s2.0-86000468041&doi=10.1108%2fQAE-12-2024-0271&partnerID=40&md5=a735463e787c53b36005e0701a7919cb","School of Civil Engineering, College of Engineering, Universiti Teknologi MARA, Selangor, Malaysia","Che Ibrahim C.K.I., School of Civil Engineering, College of Engineering, Universiti Teknologi MARA, Selangor, Malaysia; Ahmad Kamal N., School of Civil Engineering, College of Engineering, Universiti Teknologi MARA, Selangor, Malaysia","Purpose: This study aims to analyze research trends in civil engineering education accreditation, focusing on influential authors, top journals, leading institutions and countries and frequently cited articles. It also explores key research themes and proposes potential directions for future research in civil engineering education accreditation domain. Design/methodology/approach: Data were retrieved from the Scopus database for the period 1985–2024, targeting articles referencing accreditation in civil engineering education. Performance analysis was conducted using Microsoft Excel, OpenRefine and biblioMagika, while science mapping was performed with the Bibliometrix R Package and VOSviewer. Findings: The analysis demonstrates a consistent growth in publications on civil engineering education accreditation since 2000, with the United States leading contributions and Malaysia emerging as a notable contributor among developing countries. Contributions from 226 authors across worldwide institutions were identified. Six key research clusters were uncovered: (1) curricula and accreditation, (2) analytical and problem-solving skills, (3) construction practices and safety engineering, (4) undergraduate civil engineering programs, (5) professional standards in civil engineering and (6) research activities and development. Practical implications: The findings provide valuable insights for institutions offering civil engineering programs, highlighting the need to align curricula with accreditation frameworks to ensure educational quality. Emphasis is placed on integrating elements such as outcome-based education, competency development and continuous quality improvement to prepare graduates for industry demands and global professional standards. Originality/value: By offering a foundational framework for understanding the evolving landscape of accreditation, this study provides valuable guidance for institutions aiming to enhance educational quality and achieve alignment with international standards. © 2024, Emerald Publishing Limited.","Accreditation; Bibliometric; Civil engineering; Quality","","","","","","","","Abudayyeh O., Russell J., Johnston D., Rowings J., Construction engineering and management undergraduate education, Journal of Construction Engineering and Management, 126, 3, pp. 169-175, (2000); Ahmi A., bibliomagika, (2024); Alhorani R.A.M., Abu Elhaija W., Bazlamit S.M., Ahmad H.S., ABET accreditation requirements and preparation: lessons learned from a case study of civil engineering program, Cogent Engineering, 8, 1, (2021); Anwar A.A., Richards D.J., The Washington accord and U.S. licensing boards, Journal of Professional Issues in Engineering Education and Practice, 141, 4, (2015); Anwar A.A., Richards D.J., Comparison of EC and ABET accreditation criteria, Journal of Professional Issues in Engineering Education and Practice, 144, 3, (2018); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bechtel A.J., Yan K.C., Evaluation of student perceptions of sustainability in design: a pilot study, ASEE Annual Conference and Exposition, Conference Proceedings, (2018); Bosela P.A., Delatte N.J., Use of failure case studies in a construction planning and estimating course, Structures Congress 2011., (2012); Che Ibrahim C.K.I., Belayutham S., Mohammad M.Z., Prevention through design (PtD) education for future civil engineers in Malaysia: the current state, challenges and the way forward, J. Civ. Eng. Educ, 147, 1, (2021); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Delatte N.J., Bosela P.A., Sutton R., Bagaka's J., Implementing forensics and failures in the civil engineering curriculum, Forensic Engineering: From Failure to Understanding, 36130, pp. 59-70, (2009); Estes A.C., Welch R.W., Ressler S.J., Program assessment: A structured, systematic, sustainable example for civil engineers, International Journal of Engineering Education, 24, 5, pp. 864-876, (2008); Feisel L.D., Accreditation: Quality assurance for education, IEEE Potentials, 28, 4, pp. 25-27, (2009); Frank T., DePorres D., Sloan J., Work in progress: developing a foundational engineering course to improve students’ sense of belonging and increase diversity, ASEE Annual Conference and Exposition, Conference Proceedings, (2023); Gagnon W., Liu M.C., Bhargava S., Kennington A., Howard C., Calling for engineering curricula that address the climate emergency: a brief case study of civil engineering programs, Proceedings of the 5th International Conference on Building Energy and Environment, (2021); Grigg N.S., Criswell M.E., Siller T.J., Fontane D.G., Sunada D.K., Saito L., Integrated civil engineering curriculum: five-year review, Journal of Professional Issues in Engineering Education and Practice, 130, 3, pp. 160-165, (2004); Gunnink B., How the civil engineering BOK2 can be implemented at MT state university, ASEE Annual Conference and Exposition, Conference Proceedings, (2010); Gwinn A.F., Gary T., The path from community college to engineering bachelor’s degree through partnerships and NSF S-STEM funded scholarships paper presented at 2021 ASEE virtual annual conference content access, Virtual Conference, (2021); Hamilton S.R., Saftner D.A., Saviz C.M., Civil engineering program criteria: a snapshot of how programs meet the criteria, Proceedings of the ASEE Annual Conference and Exposition, Conference Proceedings, (2019); Ho J., Kortian V., Huda N., Lee A., Engineering management education: Washington accord accreditation programs, Engineering Management Journal, 36, 4, pp. 353-365, (2024); Hudyma N., Woolschlager J., Incorporating Geo-Sustainability concepts in shrinking geotechnical curricula and the new FE requirements proceedings of the, Geo-Chicago 2016., (2016); Khan M.I., Mourad S.M., Zahid W.M., Developing and qualifying civil engineering programs for ABET accreditation, Journal of King Saud University - Engineering Sciences, 28, 1, pp. 1-11, (2016); Kipfmiller T.E., Tucker A., Reeves C.J.R., Parker N.R., Katalenich S.M., Integrating professional credentialing in sustainability into civil engineering curriculum: a case study, American Society for Engineering Education Annual Conference and Exposition, (2024); Koehn E., Engineering perceptions of ABET accreditation criteria, Journal of Professional Issues in Engineering Education and Practice, 123, 2, pp. 66-70, (1997); Koehn E., Professional design component for civil engineering curriculums, Journal of Professional Issues in Engineering Education and Practice, 125, 2, pp. 35-39, (1999); Koehn E., Engineering experience and competitions implement ABET criteria, Journal of Professional Issues in Engineering Education and Practice, 132, 2, pp. 138-144, (2006); Kumar A., Paliwal J., Singh M., Pendse V., Gade R., Palav M., Raibagkar S., Focused literature review on accreditation and quality assurance: insights and future research agenda, Quality Assurance in Education, (2024); Li H., Fryer L.K., Chu S.K.W., Utilising gamified formative assessment to support English language learning in schools: a scoping review, Innovation in Language Learning and Teaching, (2024); Lin X., Yu Y., An integrated bibliometric analysis and systematic review modeling students’ technostress in higher education, Behaviour and Information Technology, 1, 1, pp. 1-25, (2024); McCuen R.H., One plus one makes thirty, Journal of Professional Issues in Engineering, 111, 3, pp. 88-99, (1985); Mazumder F.Q., Sheikh M.R., Hossain M.S., Integration of Simulation-Based learning in undergraduate engineering and technology courses, Proceedings of the American Society for Engineering Education Annual Conference and Exposition, (2024); Mohamad M., Lian O.C., Zain M.R.M., Yunus B.M., Sidek N.H., Student attainment measurement system in civil engineering undergraduate programme: a satisfaction survey, Asian Journal of University Education, 17, 2, pp. 191-202, (2021); Pilotte M.K., Dionne R., Three-year capstone design: An innovative interdisciplinary preparation for authentic engineering practice, ASEE Annual Conference and Exposition, Conference Proceedings, (2023); Pocock J., Kuennen S., Construction as the integrating element of a comprehensive civil engineering curriculum, Proceedings of the ASEE Annual Conference and Exposition, (2007); Qiu S., Natarajarathinam M., Fifty-three years of the journal of engineering education: A bibliometric overview, Journal of Engineering Education, 113, 4, pp. 767-786, (2023); Rocha B., Hill A.T., Hedgecock N., Franz S., Ernst M.P., Sallot M., Evidence of the benefits of interdisciplinary engineering teams: Incorporating systems engineering into civil engineering design, Proceedings of the American Society for Engineering Education Annual Conference and Exposition, (2022); Russell J.S., Stouffer W.B., Survey of the national civil engineering curriculum, Journal of Professional Issues in Engineering Education and Practice, 131, 2, pp. 118-128, (2005); Said S.M., Chow C.-O., Mokhtar N., Ramli R., Tuan Ya T.M.Y.S., Mohd Sabri M.F., Accreditation of engineering programs: An evaluation of current practices in Malaysia, International Journal of Technology and Design Education, 23, 2, pp. 313-328, (2013); Seagren E.A., Davis A.P., Integrating fundamental science and engineering concepts into a civil engineering sustainability, Journal of Professional Issues in Engineering Education and Practice, 137, 4, pp. 183-188, (2011); Shane J.S., Karabulut-Ilgu A., Jahren C.T., Assessing ABET outcomes in construction engineering curriculum, Construction Research Congress 2018:Sustainable Design and Construction and Education, pp. 118-127, (2018); Swenty M., Swenty B.J., A comparison of licensed engineers’ conduct requirements, the ASCE code of ethics, and EAC-ABET civil engineering accreditation criteria, Proceedings of the ASEE Annual Conference and Exposition, (2022); Swenty M.K., Swenty B.J., A study of EAC-ABET civil engineering accreditation curriculum requirements and exemption provisions of state licensure laws and rules, Proceedings of the ASEE Annual Conference and Exposition, (2023); Tymvios N., Christou E., Tenure: perceptions of requirements and impediments for civil engineering and construction disciplines, ASEE Annual Conference and Exposition, Conference Proceedings, (2019); Uziak J., Oladiran M.T., Walczak M., Gizejowski M., Is accreditation an opportunity for positive change or a mirage?, Journal of Professional Issues in Engineering Education and Practice, 140, 1, (2014); Van Eck N.J., Waltman L., VOSviewer manual: Manual for VOSViewer version 1.6”, 10, Universiteit Leiden and CWTS Meaningful Metrics, 1, pp. 1-53, (2019); Welch R., Implementing a student Design-Build project in one semester, Proceedings of the ASEE Annual Conference and Exposition, (2004); Woelfel C., Rocha M.B., McMullen K.F., Scruggs M.K.T., Salem T., Hill A.T., How do we take full advantage of the academic benefits of student competitions?, ASEE Annual Conference and Exposition, Conference Proceedings, (2024); Yehia S., AlHamaydeh M., Abdelfatah A., Tabsh S., ABET-accredited civil engineering programmes following track system: Part I -survey and framework development, Global Journal of Engineering Education, 14, 1, pp. 69-76, (2012); Zhang J., Schmidt K., Li H., BIM and sustainability education: incorporating instructional needs into curriculum planning in CEM programs accredited by ACCE, Sustainability (Sustainability), 8, 6, (2016); Zhang J., Wu W., Li H., Enhancing building information modeling competency among civil engineering and management students with team-based learning, Journal of Professional Issues in Engineering Education and Practice, 144, 2, (2018)","C.K.I. Che Ibrahim; School of Civil Engineering, College of Engineering, Universiti Teknologi MARA, Selangor, Malaysia; email: chekhairil449@uitm.edu.my","","Emerald Publishing","","","","","","09684883","","","","English","Qual. Assur. Educ.","Review","Article in press","","Scopus","2-s2.0-86000468041" -"Chen Z.; Liu Z.; Feng Y.; Shi A.; Wu L.; Sang Y.; Li C.","Chen, Ziyi (58910912300); Liu, Zhiliang (58910912400); Feng, Yali (58910721700); Shi, Aochen (58911120400); Wu, Liqing (7404904329); Sang, Yi (36464207300); Li, Chenxi (57221911756)","58910912300; 58910912400; 58910721700; 58911120400; 7404904329; 36464207300; 57221911756","Global research on RNA vaccines for COVID-19 from 2019 to 2023: a bibliometric analysis","2024","Frontiers in Immunology","15","","1259788","","","","4","10.3389/fimmu.2024.1259788","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186247847&doi=10.3389%2ffimmu.2024.1259788&partnerID=40&md5=1ba7621877b255a21390c6c79daeac41","Center for Molecular Diagnosis and Precision Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China; Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, the First Hospital of Nanchang, Nanchang, China; Department of Pathology, Jiangxi Cancer Hospital, Nanchang, China; Department of Pathology, Jiangxi Provincial Chest Hospital, Nanchang, China","Chen Z., Center for Molecular Diagnosis and Precision Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China, Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, the First Hospital of Nanchang, Nanchang, China; Liu Z., Department of Pathology, Jiangxi Cancer Hospital, Nanchang, China; Feng Y., Department of Pathology, Jiangxi Provincial Chest Hospital, Nanchang, China; Shi A., Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, the First Hospital of Nanchang, Nanchang, China; Wu L., Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, the First Hospital of Nanchang, Nanchang, China; Sang Y., Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, the First Hospital of Nanchang, Nanchang, China; Li C., Center for Molecular Diagnosis and Precision Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China, Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, the First Hospital of Nanchang, Nanchang, China","Background: Since the global pandemic of COVID-19 has broken out, thousands of pieces of literature on COVID-19 RNA vaccines have been published in various journals. The overall measurement and analysis of RNA vaccines for COVID-19, with the help of sophisticated mathematical tools, could provide deep insights into global research performance and the collaborative architectural structure within the scientific community of COVID-19 mRNA vaccines. In this bibliometric analysis, we aim to determine the extent of the scientific output related to COVID-19 RNA vaccines between 2019 and 2023. Methods: We applied the Bibliometrix R package for comprehensive science mapping analysis of extensive bibliographic metadata retrieved from the Web of Science Core Collection database. On January 11th, 2024, the Web of Science database was searched for COVID-19 RNA vaccine-related publications using predetermined search keywords with specific restrictions. Bradford’s law was applied to evaluate the core journals in this field. The data was analyzed with various bibliometric indicators using the Bibliometrix R package. Results: The final analysis included 2962 publications published between 2020 and 2023 while there is no related publication in 2019. The most productive year was 2022. The most relevant leading authors in terms of publications were Ugur Sahin and Pei-Yong, Shi, who had the highest total citations in this field. The core journals were Vaccines, Frontiers in Immunology, and Viruses-Basel. The most frequently used author’s keywords were COVID-19, SARS-CoV-2, and vaccine. Recent COVID-19 RNA vaccine-related topics included mental health, COVID-19 vaccines in humans, people, and the pandemic. Harvard University was the top-ranked institution. The leading country in terms of publications, citations, corresponding author country, and international collaboration was the United States. The United States had the most robust collaboration with China. Conclusion: The research hotspots include COVID-19 vaccines and the pandemic in people. We identified international collaboration and research expenditure strongly associated with COVID-19 vaccine research productivity. Researchers’ collaboration among developed countries should be extended to low-income countries to expand COVID-19 vaccine-related research and understanding. Copyright © 2024 Chen, Liu, Feng, Shi, Wu, Sang and Li.","bibliometrics; COVID-19; RNA vaccines; SARS-CoV-2; web of science","Bibliometrics; COVID-19; COVID-19 Vaccines; Humans; mRNA Vaccines; RNA; SARS-CoV-2; RNA vaccine; SARS-CoV-2 vaccine; tozinameran; RNA; RNA vaccine; SARS-CoV-2 vaccine; Article; bibliometrics; China; coronavirus disease 2019; drug efficacy; drug safety; human; immunology; mental health; metadata; pandemic; publication; research; Severe acute respiratory syndrome coronavirus 2; United States; vaccination; Web of Science; bibliometrics; coronavirus disease 2019","","tozinameran, 2417899-77-3; RNA, 63231-63-0; COVID-19 Vaccines, ; mRNA Vaccines, ; RNA, ","","","Natural Science Foundation of Nanchang Municipality; Natural Science Foundation of Jiangxi Province, (20204BCJL23052, 20212ACB216013); Natural Science Foundation of Jiangxi Province","The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was supported by the Jiangxi Provincial Natural Science Foundation of China (20204BCJL23052, 20212ACB216013) and by Nanchang Natural Science Foundation No.129 in 2021. 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Li; Center for Molecular Diagnosis and Precision Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China; email: pamelalee@nwafu.edu.cn; Y. Sang; Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment, the First Hospital of Nanchang, Nanchang, China; email: ndsfy001889@ncu.edu.cn","","Frontiers Media SA","","","","","","16643224","","","38426106","English","Front. Immunol.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85186247847" -"Yalcinkaya T.; Cinar Yucel S.","Yalcinkaya, Turgay (57976961500); Cinar Yucel, Sebnem (51161095400)","57976961500; 51161095400","Bibliometric and content analysis of ChatGPT research in nursing education: The rabbit hole in nursing education","2024","Nurse Education in Practice","77","","103956","","","","20","10.1016/j.nepr.2024.103956","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85190890296&doi=10.1016%2fj.nepr.2024.103956&partnerID=40&md5=314cbf153785c066c129501411ddc12a","Faculty of Health Sciences, Department of Nursing, Sinop University, Sinop, Turkey; Nursing Faculty, Department of Fundamentals of Nursing, Ege University, Izmir, Turkey","Yalcinkaya T., Faculty of Health Sciences, Department of Nursing, Sinop University, Sinop, Turkey; Cinar Yucel S., Nursing Faculty, Department of Fundamentals of Nursing, Ege University, Izmir, Turkey","Aim: This study was conducted to perform the bibliometric and content analysis of ChatGPT studies in nursing education. Background: ChatGPT is an artificial intelligence-based chatbot developed by OpenAI. The benefits and limitations of the use of ChatGPT in nursing education are still discussed; however, it is a tool having potential to be used in nursing education. Design: Bibliometric and content analysis. Methods: The study data were scanned through Scopus and Web of Science. Bibliometric analysis was carried out with VOSViewer and Bibliometrix software. In the bibliometric analysis, science mapping and performance analysis techniques were used. Various bibliometric data, including most cited publications, journals and countries, were analyzed and visualized. The synthetic knowledge synthesis method was used in content analysis. Results: We analyzed 53 publications to which 151 authors contributed. The publications had been published in 29 different journals. The average number of citations of publications is 8.2. It was determined that most of the articles were published in Nurse Education Today and Nurse Educator journals and that the leading countries were the USA and Canada. It was observed that international cooperation on the issue was weak. The most frequently mentioned keywords in the publications were ""ChatGPT"", “artificial intelligence” and ""nursing"". The following three themes emerged after the content analysis: (1) Integration of ChatGPT into nursing education; (2) Potential benefits and limitations of ChatGPT; and (3) Stepping down the rabbit hole. Conclusions: We expect that the results of the study can give nursing faculties and academics ideas about the current status of ChatGPT in nursing education and enable them to make inferences for the future. © 2024 Elsevier Ltd","Artificial intelligence; Bibliometrics analysis; ChatGPT; Nursing education; Nursing students; OpenAI","Artificial Intelligence; Bibliometrics; Education, Nursing; Humans; artificial intelligence; bibliometrics; human; nursing education","","","","","","","Abdulai A.-F., Hung L., Will ChatGPT undermine ethical values in nursing education, research and practice?, Nurs. Inq., 30, 3, pp. 3-5, (2023); Ahmed S.K., The impact of ChatGPT on the nursing profession: revolutionizing patient care and education, Ann. Biomed. Eng., 51, 11, pp. 2351-2352, (2023); Allen C., Woodnutt S., Can ChatGPT pass a nursing exam?, Int. J. Nurs. Stud., 145, (2023); Archibald M.M., Clark A.M., ChatGTP: What is it and how can nursing and health science education use it?, J. Adv. 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Stud., 153, 201), (2024); Sun G.H., Hoelscher S.H., The ChatGPT storm and what faculty can do, pp. 1-6, (2023); Taira K., Itaya T., Hanada A., Performance of the large language model ChatGPT on the National Nurse Examinations in Japan: Evaluation Study, JMIR Nurs., 6, 1), (2023); Tam W., Huynh T., Tang A., Luong S., Khatri Y., Zhou W., Nursing education in the age of artificial intelligence powered Chatbots (AI-Chatbots): are we ready yet?, Nurse Educ. Today, 129, July), (2023); Thakur A., Parikh D., Thakur A., ChatGPT in nursing education: Is there a role for curriculum development?, Teach. Learn. Nurs., 18, 3, pp. 450-451, (2023); Vaughn J., Ford S.H., Scott M., Jones C., Lewinski A., Enhancing healthcare education: leveraging ChatGPT for innovative simulation scenarios, Clin. Simul. Nurs., 87, (2024); Vitorino L.M., (2023); Woodnutt S., Allen C., Snowden J., Flynn M., Hall S., Libberton P., Purvis F., Could artificial intelligence write mental health nursing care plans?, J. Psychiatr. Ment. Health Nurs., July, pp. 1-8, (2023); Zong H., Li J., Wu E., Wu R., Lu J., Shen B., Performance of ChatGPT on Chinese national medical licensing examinations: a five-year examination evaluation study for physicians, pharmacists and nurses, BMC Med. Educ., 24, 1, (2024); Zupic I., Cater T., Bibliometric methods in management and organization, Organ. Res. Methods, 18, 3, pp. 429-472, (2015)","T. Yalcinkaya; Faculty of Health Sciences, Department of Nursing, Sinop University, Sinop, Turkey; email: tyalcinkaya@sinop.edu.tr","","Elsevier Ltd","","","","","","14715953","","","38653086","English","Nurse Educ. Pract.","Article","Final","","Scopus","2-s2.0-85190890296" -"Unaldi N.","Unaldi, Nurdan (57200279532)","57200279532","Analysis of child abuse by science mapping method","2024","Child Abuse Review","33","1","e2845","","","","0","10.1002/car.2845","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85171362427&doi=10.1002%2fcar.2845&partnerID=40&md5=d25e4b6f690338b871a48fe6e0ede22f","Child and Adolescent Psychiatry Clinic, Private Practice Istanbul, Istanbul, Turkey","Unaldi N., Child and Adolescent Psychiatry Clinic, Private Practice Istanbul, Istanbul, Turkey","Child abuse is defined as physical and emotional maltreatment, sexual abuse, neglect and exploitation that cause actual or potential harm to the child's health, development, or dignity. Bibliometrics analyses works produced in a particular field, period and region. It is used to determine the studies carried out in any field, their development and changes in the process, and possible trends. The Web of Science Core Collection database was preferred due to the vast amount of high-quality and effective scientific articles accepted in academic environments worldwide. The data obtained from the database were extracted and filtered. The Bibliometrix program was used to perform a bibliometric analysis of the data obtained from the database. In our research, 2684 articles were analysed. The first scientific study on child abuse research was entered into the database in 1980. It was used in 786 sources and 2684 documents between 1980 and 2021. Child Abuse & Neglect is the journal with the most publications, representing 15.05 per cent (404/2684) of the total articles. The publication of articles on child abuse in journals started in the 1980s. An increase was observed in the number of articles published in the following years. © 2023 Association of Child Protection Professionals and John Wiley & Sons Ltd.","bibliometric analysis; child abuse; science mapping","article; bibliometrics; child abuse; human; neglect; Web of Science","","","","","","","Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Austin A.E., Lesak A.M., Shanahan M.E., Risk and protective factors for child maltreatment: a review, Current Epidemiology Reports, 7, 4, pp. 334-342, (2020); Bernstein D.P., Fink L., Handelsman L., Foote J., Lovejoy M., Wenzel K., Et al., Initial reliability and validity of a new retrospective measure of child abuse and neglect, The American Journal of Psychiatry, 151, 8, pp. 1132-1136, (1994); Brown J., Cohen P., Johnson J.G., Salzinger S., A longitudinal analysis of risk factors for child maltreatment: findings of a 17-year prospective study of officially recorded and self-reported child abuse and neglect, Child Abuse & Neglect, 22, 11, pp. 1065-1078, (1998); 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Gonzalez D., Bethencourt Mirabal A., McCall J.D., Child abuse and neglect, (2022); Hampton R.L., Newberger E.H., Child abuse incidence and reporting by hospitals: significance of severity, class, and race, American Journal of Public Health, 75, 1, pp. 56-60, (1985); Harzing A., Reflections on the h-index, Business & Leadership, 1, 9, pp. 101-106, (2012); Jones R., Flaherty E.G., Binns H.J., Price L.L., Slora E., Abney D., Et al., Clinicians' description of factors influencing their reporting of suspected child abuse: report of the Child Abuse Reporting Experience Study Research Group, Pediatrics, 122, 2, pp. 259-266, (2008); Kamdem J.P., Duarte A.E., Lima K.R.R., Rocha J.B.T., Hassan W., Barros L.M., Et al., Research trends in food chemistry: a bibliometric review of its 40 years anniversary (1976–2016), Food Chemistry, 294, pp. 448-457, (2019); Keenan H.T., Campbell K.A., Page K., Cook L.J., Bardsley T., Olson L.M., Perceived social risk in medical decision-making for physical child abuse: a mixed-methods study, BMC Pediatrics, 17, 1, (2017); Kurutkan M.N., Orhan F., Kalite Prensiplerinin Görsel Haritalama Tekniğine Göre Bibliyometrik Analizi, (2018); Liu B.C.C., Vaughn M.S., Legal and policy issues from the United States and internationally about mandatory reporting of child abuse, International Journal of Law and Psychiatry, 64, pp. 219-229, (2019); Liu W., A matter of time: publication dates in Web of Science Core Collection, Scientometrics, 126, 1, pp. 849-857, (2021); Lyu Y., Chow J.C.-C., Hwang J.-J., Exploring public attitudes of child abuse in mainland China: a sentiment analysis of China's social media Weibo, Children and Youth Services Review, 116, (2020); Marshakova I.V., System of document connections based on references, Nauchno-Tekhnicheskaya Informatsiya Seriya 2-Informatsionnye Protsessy I Sistemy, 6, 4, pp. 3-8, (1973); Milner J.S., Gold R.G., Ayoub C., Jacewitz M.M., Predictive validity of the child abuse potential inventory, Journal of Consulting and Clinical Psychology, 52, 5, pp. 879-884, (1984); Nasir A., Shaukat K., Hameed I.A., Luo S., Alam T.M., Iqbal F., A bibliometric analysis of corona pandemic in social sciences: a review of influential aspects and conceptual structure, IEEE Access, 8, pp. 133377-133402, (2020); Olds D.L., Henderson C.R., Chamberlin R., Tatelbaum R., Preventing child abuse and neglect: a randomized trial of nurse home visitation, Pediatrics, 78, 1, pp. 65-78, (1986); Pezeshki A., Rahmani F., Ebrahimi Bakhtavar H., Fekri S., Battered child syndrome; a case study, Emergency (Tehran, Iran), 3, 2, pp. 81-82, (2015); Raan T., Advances in bibliometric analysis: research performance assessment and science mapping, Bibliometrics: use and abuse in the review of research performance, pp. 17-28, (2014); Rodrigues S.P., van Eck N.J., Waltman L., Jansen F.W., Mapping patient safety: a large-scale literature review using bibliometric visualisation techniques, BMJ Open, 4, 3, (2014); Saulsbury F.T., Campbell R.E., Evaluation of child abuse reporting by physicians, American Journal of Diseases of Children, 139, 4, pp. 393-395, (1985); Schoggl J.-P., Stumpf L., Baumgartner R.J., The narrative of sustainability and circular economy—a longitudinal review of two decades of research, Resources, Conservation and Recycling, 163, (2020); Shi J., Duan K., Wu G., Zhang R., Feng X., Comprehensive metrological and content analysis of the public–private partnerships (PPPs) research field: a new bibliometric journey, Scientometrics, 124, 3, pp. 2145-2184, (2020); Toda H., Inoue T., Tsunoda T., Nakai Y., Tanichi M., Tanaka T., Et al., Affective temperaments play an important role in the relationship between childhood abuse and depressive symptoms in major depressive disorder, Psychiatry Research, 236, pp. 142-147, (2016); Here's how every country ranks when it comes to child abuse and child safety, (2023); van Berkel S.R., Prevoo M.J.L., Linting M., Pannebakker F.D., Alink L.R.A., Prevalence of child maltreatment in the Netherlands: an update and cross-time comparison, Child Abuse & Neglect, 103, (2020); Wei L., Zhao Y., Bibliometric analysis of global environmental assessment research in a 20-year period, Environmental Impact Assessment Review, 50, pp. 158-166, (2015); Child maltreatment, (2021); Zeanah C.H., Humphreys K.L., Child abuse and neglect, Journal of the American Academy of Child and Adolescent Psychiatry, 57, 9, pp. 637-644, (2018); Zellman G.L., Linking schools and social services: the case of child abuse reporting, Educational Evaluation and Policy Analysis, 12, 1, pp. 41-55, (1990); Zhang J., Zhai S., Liu H., Stevenson J.A., Social network analysis on a topic-based navigation guidance system in a public health portal, Journal of the Association for Information Science and Technology, 67, 5, pp. 1068-1088, (2016)","N. Unaldi; Child and Adolescent Psychiatry Clinic, Istanbul, Turkey; email: nunaldi@yaani.com","","John Wiley and Sons Ltd","","","","","","09529136","","","","English","Child Abuse Rev.","Article","Final","All Open Access; Bronze Open Access","Scopus","2-s2.0-85171362427" -"Voutsa M.C.","Voutsa, Maria C. (57222131356)","57222131356","Disparaging humorous advertising: A bibliometric review","2024","Journal of Marketing Communications","","","","","","","1","10.1080/13527266.2024.2397648","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85203130622&doi=10.1080%2f13527266.2024.2397648&partnerID=40&md5=59aee66ef151466e43cae8f265b1caec","Department of Communication and Marketing, Cyprus University of Technology, Limassol, Cyprus","Voutsa M.C., Department of Communication and Marketing, Cyprus University of Technology, Limassol, Cyprus","The proliferation of disparaging humorous advertising (DHA) has garnered significant interest among researchers due to its dual potential to engage and offend audiences. Its potential to alienate audience segments underscores the importance of understanding its nuanced effects, particularly regarding cultural sensitivity and ethical considerations. Academic research is critical in identifying the conditions under which DHA is effective, focusing on audience demographics, cultural context, and the specific nature of the humor used. This bibliometric review encompasses 63 published articles spanning 34 years, sourced from the Scopus database. Performance analysis (via the Bibliometrix package in R) and science mapping (using VOSviewer software for visualization), including citation and co-authorship analysis and bibliographic coupling, are used to reveal and discuss seven discrete thematic areas: (1) Cross-cultural, (2) Perceived Humorousness, (3) Sharing Intention, (4) Level of Disparagement, (5) Target Audience, (6) Gender Portrayals, and (7) Parody & Satire. By analyzing these clusters, the research identifies gaps and provides managerial recommendations, contributing to more effective and responsible advertising strategies. © 2024 Informa UK Limited, trading as Taylor & Francis Group.","benign violation; comedic violence; Disparagement humor; humor; parody; satire","","","","","","","","Abhijit B., Olsen J.E., Carlet V., A Comparison of Print Advertisements from the United States and France, Journal of Advertising, 21, 4, pp. 73-81, (1992); Adler S., Kohn A., A Multimodal Analysis of a Controversial Israeli Political Campaign Ad, Social Semiotics, 33, 1, pp. 98-114, (2023); Ally S., Ooh, Eh Eh … Just One Small Cap is Enough!’ Servants, Detergents, and Their Prosthetic Significance, African Studies, 72, 3, pp. 321-352, (2013); Anderson A.K., Dissociation and Visual Arguments: Creating Customers for Levy’s Real Jewish Rye, Argumentation & Advocacy, 52, 2, pp. 109-124, (2015); Aria M., Cuccurullo C., Bibliometrix: An R-Tool for Comprehensive Science Mapping Analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Ausin J.M., Guixeres J., Bigne E., Alcaniz M., Facial Expressions to Evaluate Advertising: A Laboratory versus Living Room Study, Advances in Advertising Research VIII. 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How the Intensity of Violent and Sexual Humor, Gender and Audience Diversity Affect Sharing Intentions for Online Advertisements, Information Technology & People, (2022); Grougiou V., Balabanis G., Manika D., Does Humour Influence Perceptions of the Ethicality of Female-Disparaging Advertising?, Journal of Business Ethics, 164, 1, pp. 1-16, (2020); Gulas C.S., McKeage K.K., Weinberger M.G., It’s Just a Joke, Journal of Advertising, 39, 4, pp. 109-120, (2010); Gulas C.S., Swani K., Weinberger M.G., Audience Reaction to Comedic Advertising Violence After Exposure to Violent Media, Journal of Current Issues & Research in Advertising, 40, 1, pp. 3-19, (2019); Gulas C.S., Weinberger M.G., Humor in Advertising: A Comprehensive Analysis, (2006); Gurney D., Thomas Payne M., Parody as Brand, Convergence: The International Journal of Research into New Media Technologies, 22, 2, pp. 177-198, (2016); Hatzithomas L., Boutsouki C., Zotos Y., The Effects of Culture and Product Type on the Use of Humor in Greek TV Advertising: An Application of Speck’s Humorous Message Taxonomy, Journal of Current Issues & Research in Advertising, 31, 1, pp. 43-61, (2009); Hatzithomas L., Voutsa M.C., Boutsouki C., Zotos Y., A Superiority–Inferiority Hypothesis on Disparagement Humor: The Role of Disposition Toward Ridicule, Journal of Consumer Behaviour, 20, 4, pp. 923-941, (2021); Hatzithomas L., Zotos Y., Boutsouki C., Humor and Cultural Values in Print Advertising: A Cross‐Cultural Study, International Marketing Review, 28, 1, pp. 57-80, (2011); Hernandez-Santaolalla V., David Fernandez Gomez J., Del Mar Rubio-Hernandez M., Audiovisual Narrative Genres as a Tool for Advertising Research, Estudios sobre el mensaje periodístico, 28, 3, pp. 661-676, (2022); Hofmann J., Friedrich Ruch W., Humorous TV Ads and the 3WD: Evidence for Generalizability of Humour Appreciation Across Media?, European Journal of Humour Research, 5, 4, pp. 194-215, (2017); Jean S., Brand Parody: A Communication Strategy to Attack a Competitor, Journal of Consumer Marketing, 28, 1, pp. 19-26, (2011); Johnson M., Spilger U., Legal Considerations When Using Parodies in Advertising, Journal of Advertising, 29, 4, pp. 77-86, (2000); Karpinska-Krakowiak M., Gotcha! 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Voutsa; Department of Communication and Marketing, Cyprus University of Technology, Limassol, Cyprus; email: maria.voutsa@cut.ac.cy","","Routledge","","","","","","13527266","","","","English","J. Mark. Commun.","Review","Article in press","","Scopus","2-s2.0-85203130622" -"Al-Quaishi H.; Lu C.; Alani W.K.","Al-Quaishi, Helal (59367024100); Lu, Caijiang (54981023500); Alani, W.K. (57202462157)","59367024100; 54981023500; 57202462157","Vibration Energy Harvesting: A Bibliometric Analysis of Research Trends and Challenges","2024","Journal of Vibration Engineering and Technologies","12","Suppl 2","106466","2253","2281","28","3","10.1007/s42417-024-01533-7","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85206369010&doi=10.1007%2fs42417-024-01533-7&partnerID=40&md5=330b26183b1e1f789dbae2c60348ee46","School of Mechanical Engineering, Southwest Jiaotong University, Chengdu, 610031, China","Al-Quaishi H., School of Mechanical Engineering, Southwest Jiaotong University, Chengdu, 610031, China; Lu C., School of Mechanical Engineering, Southwest Jiaotong University, Chengdu, 610031, China; Alani W.K., School of Mechanical Engineering, Southwest Jiaotong University, Chengdu, 610031, China","Purpose: To present a comprehensive bibliometric analysis of vibration energy harvesting (VEH) research from 2005 to 2022. Methodology: Utilizing VOSviewer, CiteSpace, Bibliometrix, and Excel for bibliometric and science mapping analysis on a dataset of 284 publications from the Web of Science Core Collection Database. Findings: China leads in productivity and influence in VEH research, followed by the United States. Key trends include the integration of machine learning and artificial intelligence to enhance VEH device efficiency. Implications: Provides insights into the evolution of VEH research, identifies research frontiers, and suggests critical sub-domains for future research. Encourages researchers to consider various perspectives within the field. Originality/Value: Offers a holistic view and critical assessment of global VEH research, highlighting significant contributions, emerging topics, and future challenges. © Springer Nature Singapore Pte Ltd. 2024.","Bibliometric analysis; CiteSpace; Research trends; Scientific mapping; Vibration energy harvesting (VEH); VOSviewer","","","","","","National Natural Science Foundation of China, NSFC, (52175519, 61801402); Key Science and Technology Program of Shaanxi Province, (20JDJQ0038)","This work was supported by the National Natural Science Foundation of China (Grant Numbers 52175519 and 61801402), the Science and Technology Program of Sichuan Province (Grant Number 20JDJQ0038).","Seong S., Hu C., Lee S., Design under uncertainty for reliable power generation of piezoelectric energy harvester, J Intell Mater Syst Struct, 28, pp. 2437-2449, (2017); He X., Wen Q., Lu Z., Shang Z., Wen Z., A micro-electromechanical systems based vibration energy harvester with aluminum nitride piezoelectric thin film deposited by pulsed direct-current magnetron sputtering, Appl Energy, 228, pp. 881-890, (2018); 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Lu; School of Mechanical Engineering, Southwest Jiaotong University, Chengdu, 610031, China; email: lucaijiang@swjtu.edu.cn","","Springer","","","","","","25233920","","","","English","J. Vib. Eng. Technol.","Review","Final","","Scopus","2-s2.0-85206369010" -"Zangeronimo M.G.; Alvarenga R.R.","Zangeronimo, Marcio Gilberto (14059286300); Alvarenga, Renata Ribeiro (35098135300)","14059286300; 35098135300","Thermal manipulation during egg incubation in broiler chickens: A scientometric analysis","2025","Journal of Thermal Biology","130","","104159","","","","0","10.1016/j.jtherbio.2025.104159","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105007154858&doi=10.1016%2fj.jtherbio.2025.104159&partnerID=40&md5=db24eac55f72bb76014745b1cb6b39dc","Federal University of Lavras, MG, Lavras, Brazil","Zangeronimo M.G., Federal University of Lavras, MG, Lavras, Brazil; Alvarenga R.R., Federal University of Lavras, MG, Lavras, Brazil","Embryonic thermal manipulation (TM) is a promising strategy to mitigate the adverse effects of heat stress on poultry productivity. The aim of this study was to provide a scientometric analysis of the current literature on embryonic TM in broilers, indicating trends, geographic distribution, influential authors, and multidisciplinary links, aiming to provide a comprehensive overview. A search was carried out in December 2024 on Scopus, PubMed, Scielo, and Web of Science using the keywords (“thermal manipulation” OR “temperature manipulation” OR “temperature control” OR “incubation temperature”) AND (“incubation” OR “embryo” OR “fetal development”) AND broiler. No date restrictions or filters were applied. Only articles that evaluated the TM of embryonated eggs from broilers were selected. Using a dataset of 195 publications from 1994 to 2024, the data were analyzed with Bibliometrix and VOSviewer tools. A sharp increase in scientific output was observed in the last decade, with 71 % of studies published after 2015. Actual central themes include thermotolerance, heat stress, performance, and hatchability. Emerging themes include gene expression, antioxidant, immune response, and acute heat stress. Nine main research networks were identified, with limited interconnection. The United States, Brazil, and Turkey were identified as the main countries, and São Paulo State University, Jordan University of Science and Technology, and Wageningen University are the main research institutions. This study shows how TM during egg incubation has become important in broilers and how it can help them handle heat stress better. Future research should focus on combining TM with genetic, nutritional, and environmental strategies to make the birds more productive and sustainable. © 2025 Elsevier Ltd","Global research trend; Hatchability; Heat stress; Poultry; Science mapping; Thermotolerance","Animals; Chick Embryo; Chickens; Heat-Shock Response; Thermotolerance; antioxidant; Brazil; broiler; controlled study; egg; embryo; fetus development; gene expression; geographic distribution; hatchability; heat stress; heat tolerance; immune response; incubation temperature; nonhuman; poultry; review; scientometrics; temperature; turkey (bird); zygote; animal; chick embryo; Gallus gallus; heat shock response; heat tolerance; physiology","","","","","Fundação de Amparo à Pesquisa do Estado de Minas Gerais, FAPEMIG, (APQ-00959-21); Fundação de Amparo à Pesquisa do Estado de Minas Gerais, FAPEMIG; Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq, (303851/2019-8); Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq","Funding text 1: This work was supported by the Brazilian agencies FAPEMIG ( APQ-00959-21 ) and CNPq ( 303851/2019-8 ) ; Funding text 2: The authors thank FAPEMIG (APQ-00959-21) and CNPq (303851/2019-8) for financial assistance in conducting the research. ","Ajayi F.O., Elechi V.C., Maduabuchi V.C., Kusimi S., Oshifade E.O., PSVII-5 Heat shock protein 70 gene expression and association with morphometric and heat tolerance traits in three plumage colors of Noiler chicken exposed to acute heat stress, J. Anim. Sci., 102, pp. 443-444, (2024); Al-Zghoul M.B., Thermal manipulation during broiler chicken embryogenesis increases basal mRNA levels and alters production dynamics of heat shock proteins 70 and 60 and heat shock factors 3 and 4 during thermal stress, Poult. Sci., 97, pp. 3661-3670, (2018); Al-Zghoul M.B., Dalab A.E., Yahya I.E., Althnaian T.A., Al-Ramadan S.Y., Ali A.M., Albokhadaim I.F., El-Bahr S.M., Al Busadah K.A., Hannon K.M., Thermal manipulation during broiler chicken embryogenesis: effect on mRNA expressions of HSP108, HSP70, HSP47 and HSF-3 during subsequent post-hatch thermal challenge, Res. Vet. Sci., 103, pp. 211-217, (2015); Al-Zghoul M.B., Sukker H., Ababneh M.M., Effect of thermal manipulation of broilers embryos on the response to heat-induced oxidative stress, Poult. Sci., 98, pp. 991-1001, (2019); Almeida A.R., Morita V.S., Matos Junior J.B., Sgavioli S., Vicentini T.I., Boleli I.C., Long-lasting effects of incubation temperature during fetal development on subcutaneous adipose tissue of broilers, Front. Physiol., 13, (2022); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, J. Informetr., 11, pp. 959-975, (2017); Basaki M., Sahraiy N., Keykavusi K., Akbari G., Shahbazfar A.A., Kianifard D., Differential expression of small heat shock proteins in the brain of broiler embryo; the effects of embryonic thermal manipulation, J. Therm. 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Biol., 94, (2020); Page M.J., McKenzie J.E., Bossuyt P.M., Boutron I., Hoffmann T.C., Mulrow C.D., Shamseer L., Tetzlaff J.M., Akl E.A., Brennan S.E., Chou R., Glanville J., Grimshaw J.M., Hrobjartsson A., Lalu M.M., Li T., Loder E.W., Mayo-Wilson E., McDonald S., McGuinness L.A., Stewart L.A., Thomas J., Tricco A.C., Welch V.A., Whiting P., Moher D., The PRISMA 2020 statement: an updated guideline for reporting systematic reviews, BMJ, 372, (2021); Parsell D.A., Taulien J., Lindquist S., The role of heat-shock proteins in thermotolerance, Philos. Trans. R. Soc. Lond. B Biol. Sci., 339, pp. 279-285, (1993); Piestun Y., Druyan S., Brake J., Yahav S., Thermal manipulations during broiler incubation alter performance of broilers to 70 days of age, Poult. Sci., 92, pp. 1155-1163, (2013); Piestun Y., Shinder D., Ruzal M., Halevy O., Brake J., Yahav S., Thermal manipulations during broiler embryogenesis: effect on the acquisition of thermotolerance, Poult. 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Biol., 53, pp. 162-171, (2015); Wasti S., Sah N., Mishra B., Impact of heat stress on poultry health and performances, and potential mitigation strategies, Animals, 10, (2020); Werner C., Wecke C., Liebert F., Wicke M., Increasing the incubation temperature between embryonic day 7 and 10 has no influence on the growth and slaughter characteristics as well as meat quality of broilers, Animal, 4, pp. 810-816, (2010); Xie J., Tang L., Lu L., Zhang L., Xi L., Liu H.C., Odle J., Luo X., Differential expression of heat shock transcription factors and heat shock proteins after acute and chronic heat stress in laying chickens (Gallus gallus), PLoS One, 9, (2014); Xu P., Lin H., Jiao H., Zhao J., Wang X., Chicken embryo thermal manipulation alleviates postnatal heat stress-induced jejunal inflammation by inhibiting transient receptor potential V4, Ecotoxicol. Environ. Saf., 256, (2023); Yahav S., McMurtry J., Thermotolerance acquisition in broiler chickens by temperature conditioning early in life - the effect of timing and ambient temperature, Poult. Sci., 80, pp. 1662-1666, (2001); Yahav S., Shamai A., Haberfeld A., Horev G., Hurwitz S., Einat M., Induction of thermotolerance in chickens by temperature conditioning: heat shock protein expression, Ann. N. Y. Acad. Sci., 813, pp. 628-636, (1997); Yahav S., Shamay A., Horev G., Bar-Ilan D., Genina O., Friedman-Einat M., Effect of acquisition of improved thermotolerance on the induction of heat shock proteins in broiler chickens, Poult. Sci., 76, pp. 1428-1434, (1997); Yahav S., Shinder D., Tanny J., Cohen S., Sensible heat loss: the broiler's paradox, Worlds Poult. Sci. J., 61, pp. 419-434, (2005); Zaboli G.-R., Rahimi S., Shariatmadari F., Torshizi M.A.K., Baghbanzadeh A., Mehri M., Thermal manipulation during pre and post-hatch on thermotolerance of male broiler chickens exposed to chronic heat stress, Poult. Sci., 96, pp. 478-485, (2017)","M.G. Zangeronimo; Federal University of Lavras, Lavras, MG, Brazil; email: zangeronimo@ufla.br","","Elsevier Ltd","","","","","","03064565","","JTBID","40480154","English","J. Therm. Biol.","Review","Final","","Scopus","2-s2.0-105007154858" -"Pagliara F.; Aria M.; Mauriello F.","Pagliara, Francesca (23009970700); Aria, Massimo (23388148900); Mauriello, Filomena (35788435500)","23009970700; 23388148900; 35788435500","Transportation choice in tourism and travel: A bibliometrics literature review","2025","Models and Applications of Tourists' Travel Behavior","","","","21","46","25","0","10.1016/B978-0-443-26593-8.00002-0","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105005917102&doi=10.1016%2fB978-0-443-26593-8.00002-0&partnerID=40&md5=82ded3e9f55989f6a18de8c4fb3fd7f0","Department of Civil, Architectural and Environmental Engineering, University of Naples Federico II, Naples, Italy; Department of Economics and Statistics, University of Naples Federico II, Naples, Italy","Pagliara F., Department of Civil, Architectural and Environmental Engineering, University of Naples Federico II, Naples, Italy; Aria M., Department of Economics and Statistics, University of Naples Federico II, Naples, Italy; Mauriello F., Department of Civil, Architectural and Environmental Engineering, University of Naples Federico II, Naples, Italy","Transportation choice is a key element in the decision-making process of tourists and travelers. Understanding the factors influencing their transportation decisions is essential for improving the traveler experience, promoting sustainability, and stimulating innovation in the transportation and tourism sector. This chapter provides a bibliometric review with the aim of investigating transportation choice in tourism and travel. Using the Web of Science database, a systematic search was carried out for publications in international journals within the time period 1992 to 2023. An analysis was developed to evaluate research productivity, impact, and evolutionary trends. Specifically, a co-occurrence analysis and thematic network mapping were proposed to highlight conceptual, social, and intellectual structures of knowledge, as well as their temporal evolution. A thematic evolution analysis, dividing the dataset into two periods, clarified the trends and trajectories of research themes over time. This bibliometric review shows a synthesis of key findings, emerging trends, and methodological approaches in transportation choice in tourism and travel, providing valuable insights for future research directions and decisions in this sector. © 2025 Elsevier Inc. All rights reserved.","Bibliometrics; Bibliometrix; Literature review; Science mapping; Tourism; Transport choice","Decision making; Freight transportation; Navigation; Traffic control; Bibliometric; Bibliometrix; Decision-making process; Key elements; Literature reviews; Science mapping; Tourism sectors; Transport choice; Transportation sector; Web of Science; Travel time","","","","","","","Agag G., Brown A., Hassanein A., Shaalan A., Decoding travellers' willingness to pay more for green travel products: closing the intention-behaviour gap, J. Sustain. Tour., 28, 10, pp. 1551-1575, (2020); Alonso-Almeida M.D.M., Borrajo-Millan F., Yi L., Are social media data pushing overtourism? 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Manag., 83, (2021)","","","Elsevier","","","","","","","978-044326593-8; 978-044326592-1","","","English","Models and Applications of Tourists' Travel Behavior","Book chapter","Final","","Scopus","2-s2.0-105005917102" -"Moroz D.","Moroz, David (57210255399)","57210255399","What does terroir mean? A science mapping of a multidimensional concept","2024","Journal of Agricultural Economics","75","3","","889","913","24","1","10.1111/1477-9552.12607","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196193756&doi=10.1111%2f1477-9552.12607&partnerID=40&md5=3667b4f755a72da509009a8d9854c79e","EM Normandie Business School, Métis Lab, Clichy, France","Moroz D., EM Normandie Business School, Métis Lab, Clichy, France","Terroir is a pivotal concept in defining collective quality labels for agricultural products, such as geographical appellations. With climate change likely to significantly impact these appellations' delimitations, an in-depth understanding of terroir's various dimensions becomes imperative. Yet, the literature presents diverse and multifaceted definitions of terroir, making it a challenging concept to delineate. Utilising 913 articles from 1986 to 2023 sourced from Scopus and adhering to the SPAR-4-SLR bibliometric protocol, we conducted a science mapping that includes analysis of document co-citation, co-authorship, bibliographical coupling and keyword co-occurrence to elucidate terroir's definitions, research fields and issues. We propose a bibliometric analysis methodology that enables detailed mapping of the concept by disciplinary fields. The proposed methodology is applicable to systematic literature reviews aimed at studying a domain while incorporating the diversity of scientific disciplines in which it is investigated. Our analysis confirms that, in terms of agri-food sectors, the literature predominantly focuses on wine. More specifically, within the fields of business, economics and social sciences, the primary applications of the concept are with respect to geographical indications and climate change. Research conducted in agricultural and biological sciences facilitates a better characterisation of terroirs in terms of microbial characteristics. This increasingly enables a distinction to be made between the soil—i.e., the terroir place—and the quality of agri-food products. Future analysis can make use of this knowledge, as well as that on the cultural dimensions of terroir, to better understand the economic impacts of the different dimensions of terroir. © 2024 Agricultural Economics Society.","bibliometrix; concept; science mapping; SPAR-4-SLR protocol; terroir","agricultural production; climate change; conceptual framework; economic impact; mapping method","","","","","","","Aksnes D.W., Sivertsen G., A criteria-based assessment of the coverage of Scopus and web of science, Journal of Data and Information Science, 4, 1, pp. 1-21, (2019); Barata A., Malfeito-Ferreira M., Loureiro V., The microbial ecology of wine grape berries, International Journal of Food Microbiology, 153, 3, pp. 243-259, (2012); Barham E., Translating terroir: The global challenge of French AOC labeling, Journal of Rural Studies, 19, 1, pp. 127-138, (2003); Batat W., The role of luxury gastronomy in culinary tourism: An ethnographic study of Michelin-Starred restaurants in France, International Journal of Tourism Research, 23, 2, pp. 150-163, (2021); Berard L., Marchenay P., Terroirs, produits et enracinement, ARA (Association Rhône-Alpes d'Anthropologie), 43, Special Issue, pp. 16-17, (1998); Berno T., Fuste-Forne F., Imaginaries of cheese: Revisiting narratives of local produce in the contemporary world, Annals of Leisure Research, 23, 5, pp. 608-626, (2020); Boell S.K., Cecez-Kecmanovic D., A hermeneutic approach for conducting literature reviews and literature searches, Communications of the Association for Information Systems, 34, pp. 257-286, (2014); Brevik E.C., Steffan J.J., Rodrigo-Comino J., Neubert D., Burgess L.C., Cerda A., Connecting the public with soil to improve human health, European Journal of Soil Science, 70, 4, pp. 898-910, (2019); Callon M., Courtial J.-P., Turner W.A., Bauin S., From translations to problematic networks: An introduction to co-word analysis, Social Science Information, 22, 2, pp. 191-235, (1983); Capitello R., Agnoli L., Charters S., Begalli D., Labelling environmental and terroir attributes: Young Italian consumers' wine preferences, Journal of Cleaner Production, 304, (2021); Chalvantzi I., Banilas G., Tassou C., Nisiotou A., Biogeographical regionalization of wine yeast communities in Greece and environmental drivers of species distribution at a local scale, Frontiers in Microbiology, 12, pp. 1-12, (2021); Chang Y.-W., Huang M.-H., Lin C.-W., Evolution of research subjects in library and information science based on keyword, bibliographical coupling, and co-citation analyses, Scientometrics, 105, 3, pp. 2071-2087, (2015); Charters S., Spielmann N., Babin B.J., The nature and value of terroir products, European Journal of Marketing, 51, 4, pp. 748-771, (2017); Chen C., Ibekwe-SanJuan F., Hou J., The structure and dynamics of cocitation clusters: A multiple-perspective cocitation analysis, Journal of the American Society for Information Science and Technology, 61, 7, pp. 1386-1409, (2010); Chouvy P.-A., Moroccan hashish as an example of a cannabis terroir product, GeoJournal, 88, 4, pp. 3833-3850, (2022); Chouvy P.-A., Why the concept of terroir matters for drug cannabis production, GeoJournal, 88, 1, pp. 89-106, (2022); Crane D., Social structure in a Group of Scientists: A test of the “invisible college” hypothesis, Social networks, pp. 161-178, (1977); Cross R., Plantinga A.J., Stavins R.N., The value of terroir: Hedonic estimation of vineyard Sale prices, Journal of Wine Economics, 6, 1, pp. 1-14, (2011); Cross R., Plantinga A.J., Stavins R.N., What is the value of terroir?, American Economic Review, 101, 3, pp. 152-156, (2011); Cross R., Plantinga A.J., Stavins R.N., Terroir in the New World: Hedonic estimation of vineyard Sale prices in California, Journal of Wine Economics, 12, 3, pp. 282-301, (2017); Curzi D., Huysmans M., The impact of protecting EU geographical indications in trade agreements, American Journal of Agricultural Economics, 104, 1, pp. 364-384, (2022); Dabbous-Wach A., Rodolfi M., Paolini J., Costa J., Ganino T., Characterization of wild Corsican hops and assessment of the performances of German hops in Corsican environmental conditions through a multidisciplinary approach, Applied Sciences, 11, 9, (2021); de Oliveira Junqueira A.C., de Melo Pereira G.V., Coral Medina J.D., Alvear M.C.R., Rosero R., de Carvalho Neto D.P., Enriquez H.G., Soccol C.R., First description of bacterial and fungal communities in Colombian coffee beans fermentation analysed using Illumina-based amplicon sequencing, Scientific Reports, 9, 1, (2019); de Resseguier L., Mary S., Le Roux R., Petitjean T., Quenol H., van Leeuwen C., Temperature variability at local scale in the Bordeaux area. 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Moroz; EM Normandie Business School, Métis Lab, Clichy, 30-32 rue Henri Barbusse, 92110, France; email: dmoroz@em-normandie.fr","","John Wiley and Sons Inc","","","","","","0021857X","","","","English","J. Agric. Econ.","Article","Final","","Scopus","2-s2.0-85196193756" -"Shende R.V.; Jaipal","Shende, Rasika Vijay (59652186500); Jaipal (59651180300)","59652186500; 59651180300","A bibliometric analysis of communication and healthcare research: Global landscape with an emphasis on India","2025","Multidisciplinary Reviews","8","7","e2025223","","","","0","10.31893/multirev.2025223","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85218714124&doi=10.31893%2fmultirev.2025223&partnerID=40&md5=2a697d4dc186cee5abeeed5a814bd003","Visvesvaraya National Institute of Technology Institute, Department of Humanities and Social Sciences, Nagpur, India","Shende R.V., Visvesvaraya National Institute of Technology Institute, Department of Humanities and Social Sciences, Nagpur, India; Jaipal, Visvesvaraya National Institute of Technology Institute, Department of Humanities and Social Sciences, Nagpur, India","Healthcare systems recognized the significance of effective communication and its colossal cultural leverage. Nonetheless, attempts at bibliometric analysis to position the contemporary developments and trends in medical humanities communication from a global landscape with an emphasis on India remain scarce. Indian contribution to providing competitive healthcare regardless of its diverse nature with unique challenges captivates global scholarly attention towards communication and healthcare from the Indian context. Therefore, the present study aims to investigate the advancements in communication and healthcare research employing bibliometric analysis of 2,334 sourced from the Scopus database from 2000 to 2023. The study examined the performance and the science mapping analysis using the programs Bibliometrix and VOSviewer. Performance analysis findings indicated an increase in global publication trends after 2005, and a complex publication trend was observed in India regarding communication and healthcare research. In scientific production, the United States of America remained foremost with 3849 publications while India’s collaboration output was maximum with Brazil. Globally Dr. Erik Farin’s work was recognized and within the Indian context, Dr. Sathyaraj Venkatesan persisted as the most prominent author. “Health Communication” published rigorously on communication and healthcare on the world level and the most productive source for Indian scholars remained the “Indian Journal of Community Health”. By using keywords, the analysis indicates that subsequent research could concentrate on, “medical humanities”, “health literacy”, “communication”, and “health communication” among other areas. The overall findings establish a foundation and situate research in communication and healthcare giving impetus to future scholars, medical professionals, and policymakers for crafting medical curricula and improving healthcare practices. © 2025, Malque Publishing. All rights reserved.","bibliometric analysis; communication; health communication; healthcare; medical humanities","","","","","","","","Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Birte Snilstveit S. O., Vojtkova M., Narrative approaches to systematic review and synthesis of evidence for international development policy and practice, Journal of Development Effectiveness, 4, 3, pp. 409-429, (2012); Bittner-Fagan H., Davis J., Savoy M., Improving Patient Safety: Improving Communication, FP Essentials, 463, pp. 27-33, (2017); Bittner-Fagan H., Davis J., Savoy M., Improving Patient Safety: Improving Communication, FP Essentials, 463, pp. 27-33, (2017); Boudry C., Mouriaux F., Eye Neoplasms Research: A Bibliometric Analysis from 1966 to 2012, European Journal of Ophthalmology, 25, 4, pp. 357-365, (2015); Caffi C., Janney R. W., Toward a pragmatics of emotive communication, Journal of Pragmatics, 22, 3, pp. 325-373, (1994); Chen X., Xie H., Wang F. L., Liu Z., Xu J., Hao T., A bibliometric analysis of natural language processing in medical research, BMC Medical Informatics and Decision Making, 18, (2018); Chen X., Xie H., Wang F. L., Liu Z., Xu J., Hao T., A bibliometric analysis of natural language processing in medical research, BMC Medical Informatics and Decision Making, 18, (2018); Chichirez C.-M., Assistant P., Interpersonal communication in healthcare; Dickinson J. K., Guzman S. J., Maryniuk M. D., O'Brian C. A., Kadohiro J. K., Jackson R. A., D'Hondt N., Montgomery B., Close K. L., Funnell M. M., The use of language in diabetes care and education, Diabetes Care, 40, 12, pp. 1790-1799, (2017); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); DuBard C. A., Garrett J., Gizlice Z., Effect of Language on Heart Attack and Stroke Awareness Among U.S. Hispanics, American Journal of Preventive Medicine, 30, 3, pp. 189-196, (2006); Duong V., Bunzli S., Callahan L. F., Jong C. B., Hunter D. J., Kim J. S., Mobasheri A., Visual narratives in medicine – Bridging the gap in graphic medicine with an illustrated narrative of osteoarthritis, Osteoarthritis and Cartilage Open, 6, 2, (2024); Farooq S., Johal R. K., Ziff C., Naeem F., Different communication strategies for disclosing a diagnosis of schizophrenia and related disorders, Cochrane Database of Systematic Reviews, 2017, 10, (2017); Fernandez A., Schillinger D., Grumbach K., Rosenthal A., Stewart A. L., Wang F., Perez-Stable E. J., Physician language ability and cultural competence, Journal of General Internal Medicine, 19, 2, pp. 167-174, (2004); Green M. C., Narratives and Cancer Communication, Journal of Communication, 56, s1, pp. S163-S183, (2006); Hargie O., Dickson D., Tourish D., The world of the communicative manager, Communication Skills for Effective Management, pp. 1-34, (2004); Hempler I., Woitha K., Thielhorn U., Farin E., Post-stroke care after medical rehabilitation in Germany: a systematic literature review of the current provision of stroke patients, BMC Health Services Research, 18, 1, (2018); Hinyard L. J., Kreuter M. W., Using Narrative Communication as a Tool for Health Behavior Change: A Conceptual, Theoretical, and Empirical Overview, Health Education & Behavior, 34, 5, pp. 777-792, (2007); Keramatfar A., Amirkhani H., Bibliometrics of sentiment analysis literature, Journal of Information Science, 45, 1, pp. 3-15, (2019); Khan A., Goodell J. W., Hassan M. K., Paltrinieri A., A bibliometric review of finance bibliometric papers, Finance Research Letters, 47, (2022); Lee D., Bibliometric analysis of Asian ‘language and linguistics’ research: A case of 13 countries, Humanities and Social Sciences Communications, 10, 1, (2023); Liao H.-C., Wang Y., Storytelling in Medical Education: Narrative Medicine as a Resource for Interdisciplinary Collaboration, International Journal of Environmental Research and Public Health, 17, 4, (2020); Modi J. N., Anshu, Chhatwal J., Gupta P., Singh T., Teaching and assessing communication skills in medical undergraduate training, Indian Pediatrics, 53, 6, pp. 497-504, (2016); Moreau K. A., Eady K., Sikora L., Horsley T., Digital storytelling in health professions education: a systematic review, BMC Medical Education, 18, 1, (2018); Ousager J., Johannessen H., Humanities in Undergraduate Medical Education: A Literature Review, Academic Medicine: Journal of the Association of American Medical Colleges, 85, pp. 988-998, (2010); Pedersen R., Empirical research on empathy in medicine—A critical review, Patient Education and Counseling, 76, 3, pp. 307-322, (2009); Rachel Kornhaber Kenneth Walsh J. D., Walker K., Enhancing adult therapeutic interpersonal relationships in the acute health care setting: an integrative review, Journal of Multidisciplinary Healthcare, 9, pp. 537-546, (2016); Rees L., Friis T., Woodward-Kron R., Munsie M., What is known about healthcare professional-patient communication when discussing stem cell therapies? A scoping review, Patient Education and Counseling, 130, (2025); Rider E., Keefer C., Communication skills competencies: Definitions and a teaching toolbox, Medical Education, 40, pp. 624-629, (2006); Ross-Driscoll K., Adams A., Caicedo J., Gordon E. J., Kirk A. D., McElroy L. M., Taber D., Patzer R., Health Disparity Metrics for Transplant Centers: Theoretical and Practical Considerations, Transplantation, 108, 9, pp. 1823-1825, (2024); Saji S., Venkatesan S., Callender B., Comics in the Time of a Pan(dem)ic: COVID-19, Graphic Medicine, and Metaphors, Perspectives in Biology and Medicine, 64, 1, pp. 136-154, (2021); Shrivastava S., Bobhate Shrivastava P., Ramasamy J., Behavior change communication: A client-centered and professionally developed strategy to modify health status in developing countries, European Journal of Physical and Health Education, 6, (2014); UITTERHOEVE R. J., BENSING J. M., GROL R. P., DEMULDER P. H. M., VAN ACHTERBERG T., The effect of communication skills training on patient outcomes in cancer care: a systematic review of the literature, European Journal of Cancer Care, 19, 4, pp. 442-457, (2010); Venkatesan S., Saji S., (Un)bridgeable Chasms?: Doctor-Patient Interactions in Select Graphic Medical Narratives, Journal of Medical Humanities, 40, 4, pp. 591-605, (2019); Vermeir P., Vandijck D., Degroote S., Peleman R., Verhaeghe R., Mortier E., Hallaert G., Van Daele S., Buylaert W., Vogelaers D., Communication in healthcare: A narrative review of the literature and practical recommendations, International Journal of Clinical Practice, 69, 11, pp. 1257-1267, (2015)","","","Malque Publishing","","","","","","25953982","","","","English","Multidiscip. Rev.","Article","Final","","Scopus","2-s2.0-85218714124" -"Mazlee M.N.; Zunairah H.","Mazlee, M.N. (35262460300); Zunairah, H. (59174388200)","35262460300; 59174388200","Science mapping of catalyst support for gas adsorption applications","2024","Advances in Materials Research (South Korea)","13","3","","203","210","7","0","10.12989/amr.2024.13.3.203","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196082787&doi=10.12989%2famr.2024.13.3.203&partnerID=40&md5=9e54ba9160360aa62a3893b33540ba0d","Faculty of Mechanical Engineering and Technology, Universiti Malaysia Perlis, Perlis, Arau, 02600, Malaysia; Frontier Materials Research, Centre of Excellence (FrontMate), Perlis, Kangar, 01000, Malaysia; Faculty of Business & Management, Universiti Teknologi MARA, Perlis, Arau, 02600, Malaysia","Mazlee M.N., Faculty of Mechanical Engineering and Technology, Universiti Malaysia Perlis, Perlis, Arau, 02600, Malaysia, Frontier Materials Research, Centre of Excellence (FrontMate), Perlis, Kangar, 01000, Malaysia; Zunairah H., Faculty of Business & Management, Universiti Teknologi MARA, Perlis, Arau, 02600, Malaysia","Science mapping is a visual representation of the structure and dynamics of scholarly knowledge. Gas adsorption on catalyst supports is a crucial process in many catalytic reactions. The R package “Bibliometrix” and VosViewer software were employed for science mapping analysis. The results show that the upward trend but fluctuates from year to year for both annual scientific production and average article citations per year. Co-occurrence of the keywords were used to identify the primary fields of study and to map the existing state of research. Trending topics reveal some interesting features that support the growth of research in this field and are associated with emerging disciplines or areas of study that have not been extensively explored. Copyright © 2024 Techno-Press, Ltd.","catalyst supports; gas adsorption; keywords; science mapping","","","","","","","","Alabdullah M.A., Gomez A.R., Vittenet J., Bendjeriou-Sedjerari A., Xu W., Abba I.A., Gascon J., A viewpoint on the refinery of the future: Catalyst and pro. challenges, ACS Catalys, 10, 15, pp. 8131-8140, (2020); Boffito D.C., Van Gerven T., Process intensification and catalysis, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, (2019); Chan Wai H., Mohd Noor M., Ahmad Z.A., Jamaludin S.B., Mohd Ishak M.A., Jusoh M.S., Sustainable porous materials for gas adsorption applications; A concise review, Adv. Mater. Res, 795, pp. 96-101, (2013); Chan W.H., Mazlee M.N., Ahmad Z.A., Ishak M.A., Shamsul J.B., Effects of fly ash addition on physical properties of porous clay-fly ash composites via polymeric replica technique, J. Mater. Cycle. Waste Manag, 19, 2, pp. 794-803, (2016); Ciriminna R., Pagliaro M., Luque R., Heterogeneous catalysis underflow for the 21st-century fine chemical industry, Green Energy Env, 6, 2, pp. 161-166, (2021); Li J., Wang L., Liu Y., Song Y., Zeng P., Zhang Y., The research trends of metal-organic frameworks in environmental science: A review based on bibliometric analysis, Env. Sci. Pollut. Res, 27, 16, pp. 19265-19284, (2020); McNaught A.D., Wilkinson A., IUPAC Compendium of Chemical Terminology, (1997); Pulidindi K., Ahuja K., Catalyst Market Size, Share & Trends Analysis Report by Raw Material, by Product by Application (Heterogeneous, Homogeneous), by Region, and Segment Forecasts (2023–2030), (2023); Thangaraj B., Solomon P.R., Muniyandi B., Ranganathan S., Lin L., Catalysis in biodiesel production - A review, Clean Energy, 3, 1, pp. 2-23, (2018); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometr, 84, pp. 523-538, (2010)","M.N. Mazlee; Faculty of Mechanical Engineering and Technology, Universiti Malaysia Perlis, Arau, Perlis, 02600, Malaysia; email: mazlee@unimap.edu.my","","Techno-Press","","","","","","22340912","","","","English","Adva. Mater. Res. (South Korea)","Article","Final","","Scopus","2-s2.0-85196082787" -"Hernández-Torrano D.; Bessems K.; Buijs G.; Lassalle C.; Datema W.; Jourdan D.","Hernández-Torrano, Daniel (53986348700); Bessems, Kathelijne (15821845800); Buijs, Goof (7801424886); Lassalle, Camille (59396860900); Datema, William (59397510100); Jourdan, Didier (7004600872)","53986348700; 15821845800; 7801424886; 59396860900; 59397510100; 7004600872","Health promotion in the school context: a scientific mapping of the literature","2025","Health Education","125","1","","68","84","16","1","10.1108/HE-09-2023-0099","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85208247136&doi=10.1108%2fHE-09-2023-0099&partnerID=40&md5=b3be2f8ad483cd444d6f2a42da1ab0a5","Graduate School of Education, Nazarbayev University, Astana, Kazakhstan; Department of Health Promotion, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, Netherlands; UNESCO Chair and WHO Collaborating Center Global Health and Education, Paris, France; Maastricht University, Maastricht, Netherlands; Society for Public Health Education, Washington, DC, United States; University of Clermont Auvergne, Clermont-Ferrand, France","Hernández-Torrano D., Graduate School of Education, Nazarbayev University, Astana, Kazakhstan; Bessems K., Department of Health Promotion, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, Netherlands; Buijs G., UNESCO Chair and WHO Collaborating Center Global Health and Education, Paris, France; Lassalle C., Maastricht University, Maastricht, Netherlands; Datema W., Society for Public Health Education, Washington, DC, United States; Jourdan D., UNESCO Chair and WHO Collaborating Center Global Health and Education, Paris, France, University of Clermont Auvergne, Clermont-Ferrand, France","Purpose: This study presents an overview of research literature on health promotion in schools, utilizing metadata extracted from 4,328 publications indexed in the Scopus database over the past 35 years. Design/methodology/approach: A bibliometric approach was used to analyze the development and current state of using publication and citation data. A structured keyword search was conducted in the Scopus database to retrieve relevant publications in the field. Frequency counts, rank-ordered tables and time series charts were used to illustrate the dynamic growth of publication and citation data, the core journals, the leading countries and the most frequently used keywords in research on health promotion in school contexts. A series of social network analyses was conducted to explore and visualize the social, intellectual and conceptual structure of the field. Findings: Findings demonstrate that health promotion in the school context is a growing research field that has gained significant momentum in recent years. The research in this field is widely distributed internationally, but the research output is dominated by the US and other English-speaking countries. The study reveals a trend toward increased collaboration among research groups. The level of international collaboration varies. The research field is highly interdisciplinary, and the main research themes addressed in the literature include mental health, well-being and quality of life; health behaviors; oral health education; sexual and reproductive education and general health promotion and health education in schools. Originality/value: This is the first study to map the development of a research field with growing recognition. It provides a comprehensive overview of the emerging field of health promotion in the school context and its progress over time, contributing to the organization of the research domain. The study demonstrates the need for a new framework for health promotion research that supports the sustainability of health promotion research in schools. © 2024, Emerald Publishing Limited.","Bibliometric review; Bibliometrix; Health education; Ottawa charter; School health promotion; Science mapping; VOSviewer; Well-being","article; bibliometrics; education; health behavior; health education; health promotion; human; mental health; metadata; quality of life; school; school health service; social network analysis; speech; systematic review; time series analysis; United States; wellbeing","","","","","United Nations Educational, Scientific and Cultural Organization, UNESCO","We would like to acknowledge and thank the UNESCO Chair and WHO Collaborating Center for Global Health and Education. Through their support, the authors of this study were able to unite diverse perspectives, fostering an environment of shared knowledge that has greatly contributed to the depth and scope of our research.","Aboelela S.W., Larson E., Bakken S., Carrasquillo O., Formicola A., Glied S.A., Haas J., Gebbie K.M., Defining interdisciplinary research: conclusions from a critical review of the literature, Health Services Research, 42, 1 p1, pp. 329-346, (2007); Allensworth D.D., Kolbe L.J., The comprehensive school health program: exploring an expanded concept, Journal of School Health, 57, 10, pp. 409-412, (1987); Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bonell C., Parry W., Wells H., Jamal F., Fletcher A., Harden A., Thomas J., Campbell R., Petticrew M., Murphy S., Whitehead M., Moore L., The effects of the school environment on student health: a systematic review of multi-level studies, Health and Place, 21, pp. 180-191, (2013); Coccia M., Wang L., Evolution and convergence of the patterns of international scientific collaboration, Proceedings of the National Academy of Sciences, 113, 8, pp. 2057-2061, (2016); Craigie A.M., Lake A.A., Kelly S.A., Adamson A.J., Mathers J.C., Tracking of obesity-related behaviors from childhood to adulthood: a systematic review, Maturitas, 70, 3, pp. 266-284, (2011); Ding Y., Chowdhury G.G., Foo S., Journal as markers of intellectual space: journal co-citation analysis of information retrieval area, 1987–1997, Scientometrics, 47, 1, (2000); Dooris M., Poland B., Kolbe L., de Leeuw E., McCall D.S., Wharf-Higgins J., Healthy settings: building evidence for the effectiveness of whole system health promotion – challenges and future directions, Global Perspectives on Health Promotion Effectiveness, pp. 327-352, (2007); Falagas M.E., Pitsouni E.I., Malietzis G.A., Pappas G., Comparison of PubMed, Scopus, Web of science, and google scholar: strengths and weaknesses, The FASEB Journal, 22, 2, pp. 338-342, (2008); Hernandez-Torrano D., Mapping global research on child well-being in school contexts: a bibliometric and network analysis (1978-2018), Child Indicators Research, 13, 3, pp. 863-884, (2020); Ho Y.L., Mahirah D., Ho C.Z., Thumboo J., The role of the family in health promotion: a scoping review of models and mechanisms, Health Promotion International, 37, 6, (2022); Hollar D., Lombardo M., Lopez-Mitnik G., Hollar T.L., Almon M., Agatston A.S., Messiah S.E., Effective multi-level, multi-sector, school-based obesity prevention programming improves weight, blood pressure, and academic performance, especially among low-income, minority children, Journal of Health Care for the Poor and Underserved, 21, pp. 93-108, (2010); Hovdenak I.M., Stea T.H., Twisk J., Te Velde S.J., Klepp K.I., Bere E., Tracking of fruit, vegetables and unhealthy snacks consumption from childhood to adulthood (15-year period): does exposure to a free school fruit programme modify the observed tracking?, International Journal of Behavioral Nutrition and Physical Activity, 16, 1, (2019); Jones J.T., Furner M., WHO’s Global School Health Initiative: Health-Promoting Schools: A Healthy Setting for Living, Learning and Working, (1998); Jourdan D., Gray N.J., Barry M.M., Caffe S., Cornu C., Diagne F., El Hage F., Farmer M.Y., Slade S., Marmot M., Sawyer S.M., Supporting every school to become a foundation for healthy lives, Lancet Child and Adolescent Health, 5, 4, pp. 295-303, (2021); Jourdan D., Potvin L., Global handbook of health promotion research, Doing Health Promotion Research, 3, (2023); Keshavarz Mohammadi N., One step back toward the future of health promotion: complexity-informed health promotion, Health Promotion International, 34, 4, pp. 635-639, (2019); Kivits J., Ricci L., Minary L., Interdisciplinary research in public health: the ‘why’ and the ‘how, Journal of Epidemiology and Community Health, 73, 12, pp. 1061-1602, (2019); Leger L.S., Buijs G., Mohammadi N.K., Lee A., Health-promoting schools, Handbook of Settings-Based Health Promotion, 105, pp. 105-117, (2022); Mongeon P., Paul-Hus A., The journal coverage of web of science and scopus: a comparative analysis, Scientometrics, 106, 1, pp. 213-228, (2016); Newman M.E.J., Coauthorship networks and patterns of scientific collaboration, Proceedings of the National Academy of Sciences, 101, pp. 5200-5205, (2004); Niu L., Hoyt L.T., Pachucki M.C., Context matters: adolescent neighborhood and school influences on young adult body mass index, Journal of Adolescent Health, 64, 3, pp. 405-410, (2019); Norris M., Oppenheim C., Comparing alternatives to the web of science for coverage of the social sciences’ literature, Journal of Informetrics, 1, 2, pp. 161-169, (2007); Nutbeam D., The health promoting school: closing the gap between theory and practice, Health Promotion International, 7, 3, pp. 151-153, (1992); Nutbeam D., Health education and health promotion revisited, Health Education Journal, 78, 6, pp. 705-709, (2019); Potvin L., Jourdan D., Global handbook of health promotion research, Mapping Health Promotion Research, 1, (2022); Potvin L., McQueen D.V., Health Promotion Evaluation Practices in the Americas: Values and Research, (2008); Roemer R., Borchardt R., Meaningful Metrics: A 21st-Century Librarian’s Guide to Bibliometrics, Altmetrics, and Research Impact, (2015); Rowling L., Jeffreys V., Capturing complexity: integrating health and education research to inform health-promoting schools policy and practice, Health Education Research, 21, 5, pp. 705-718, (2006); Sawyer S.M., Raniti M., Aston R., Making every school a health-promoting school, The Lancet Child and Adolescent Health, 5, 8, pp. 539-540, (2021); Singh V.K., Singh P., Karmakar M., Leta J., Mayr P., The journal coverage of web of science, scopus and dimensions: a comparative analysis, Scientometrics, 126, 6, pp. 5113-5142, (2021); Turunen H., Sormunen M., Jourdan D., von Seelen J., Buijs G., Health Promoting Schools-a complex approach and a major means to health improvement, Health Promotion International, 32, 2, pp. 177-184, (2017); (2022); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, pp. 523-538, (2010); van Rijsbergen C.J., A theoretical basis for the use of co-occurrence data in information retrieval, Journal of Documentation, 33, 2, pp. 106-109, (1977); Vera-Baceta M.A., Thelwall M., Kousha K., Web of science and scopus language coverage, Scientometrics, 121, 3, pp. 1803-1813, (2019); Health promotion: Ottawa charter, (1995); Global Status report on noncommunicable diseases, (2014); Declaration: partnerships for the health and well-being of our young and future generations, Working Together for Better Health and Well-Being: Promoting Intersectoral and Interagency Action for Health and Well-Being the WHO European Region, (2016); Health promotion glossary of terms, (2021); Young I., Health promotion in schools-a historical perspective, Global Health Promotion Promot Educ, 12, 3-4, pp. 112-117, (2005); Young I., St Leger L., Buijs G., School Health Promotion: Evidence for Effective Action, 16, pp. 1-23, (2013)","D. Hernández-Torrano; Graduate School of Education, Nazarbayev University, Astana, Kazakhstan; email: daniel.torrano@nu.edu.kz","","Emerald Publishing","","","","","","09654283","","","","English","Health Educ.","Article","Final","","Scopus","2-s2.0-85208247136" -"da Silva Souza L.R.; da Silva D.H.; Ribeiro C.T.; da Silva D.A.; Nasuto S.J.; Sweeney-Reed C.M.; de Oliveira Andrade A.; Pereira A.A.","da Silva Souza, Leandro Rodrigues (59124817000); da Silva, Daniel Hilário (58651859500); Ribeiro, Caio Tonus (58650714300); da Silva, Daiane Alves (59893582500); Nasuto, Slawomir J. (9275024700); Sweeney-Reed, Catherine M. (9275024900); de Oliveira Andrade, Adriano (57216429605); Pereira, Adriano Alves (7402230064)","59124817000; 58651859500; 58650714300; 59893582500; 9275024700; 9275024900; 57216429605; 7402230064","PubMedMetaTool: Automated metadata extraction from PubMed using Python for bibliometric analysis","2025","Software Impacts","24","","100766","","","","0","10.1016/j.simpa.2025.100766","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105004915901&doi=10.1016%2fj.simpa.2025.100766&partnerID=40&md5=1fc611d0643980f9c3dc13c5b4e4f357","Programa de Pós-Graduação em Engenharia Biomédica, Uberlândia, Brazil; Instituto Federal Goiano – Campus Cristalina, Cristalina, Brazil; Instituto Federal Goiano – Campus Rio Verde, Rio Verde, Brazil; Faculdade de Engenharia Elétrica, Uberlândia, Brazil; Programa de Pós- Graduação em Estudo Literário, Uberlândia, Brazil; Neurocybernetics and Rehabilitation, Dept. of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany; Biomedical Sciences and Biomedical Engineering Division, School of Biological Sciences, University of Reading, Reading, United Kingdom","da Silva Souza L.R., Programa de Pós-Graduação em Engenharia Biomédica, Uberlândia, Brazil, Instituto Federal Goiano – Campus Rio Verde, Rio Verde, Brazil; da Silva D.H., Programa de Pós-Graduação em Engenharia Biomédica, Uberlândia, Brazil, Instituto Federal Goiano – Campus Cristalina, Cristalina, Brazil; Ribeiro C.T., Programa de Pós-Graduação em Engenharia Biomédica, Uberlândia, Brazil; da Silva D.A., Programa de Pós- Graduação em Estudo Literário, Uberlândia, Brazil; Nasuto S.J., Neurocybernetics and Rehabilitation, Dept. of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany; Sweeney-Reed C.M., Biomedical Sciences and Biomedical Engineering Division, School of Biological Sciences, University of Reading, Reading, United Kingdom; de Oliveira Andrade A., Programa de Pós-Graduação em Engenharia Biomédica, Uberlândia, Brazil, Faculdade de Engenharia Elétrica, Uberlândia, Brazil; Pereira A.A., Programa de Pós-Graduação em Engenharia Biomédica, Uberlândia, Brazil, Faculdade de Engenharia Elétrica, Uberlândia, Brazil","Bibliometric analyses often depend on extracting metadata from large scientific databases, a process that is still largely manual, repetitive, and error prone. This paper presents PubMedMetaTool, an open-source Python-based solution that automates the retrieval and transformation of bibliographic metadata from PubMed, using either article titles or Digital Object Identifiers as input. The tool implements a modular pipeline that extracts metadata using NCBI's Entrez programming utilities and transforms it into formats compatible with tools such as Bibliometrix, VOSviewer, and pyBibX. Designed to be transparent and configurable, the tool improves bibliometric workflow efficiency, accuracy, and interoperability workflows. © 2025 The Author(s)","Bibliometric analysis; Bibliometric database; Bibliometrix; PubMed; Science mapping; VoSViewer","","","","","","Centre for Innovation and Technology Assessment in Health; CEAGRE; Instituto Federal Goiás, IFGOIANO; NIATS; Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES; Fundação de Amparo à Pesquisa do Estado de Goiás, FAPEG; Universidade Federal de Uberlândia, UFU; Michael J. Fox Foundation for Parkinson's Research, MJFF; Center of Excellence in Exponential Agriculture; Fundação de Amparo à Pesquisa do Estado de Minas Gerais, FAPEMIG, (302942/2022-0, 309525/2021-7); Fundação de Amparo à Pesquisa do Estado de Minas Gerais, FAPEMIG","The present study was carried out with the support of the National Council for Scientific and Technological Development (CNPq), Coordination for the Improvement of Higher Education Personnel (CAPES), along with the Foundation for Research Support of the State of Minas Gerais (FAPEMIG). A.O.A. (302942/2022-0) and A.A.P. (309525/2021-7) are fellows of CNPq, Brazil. We express our gratitude to the Michael J. Fox Foundation (MJFF) for promoting public awareness of the scientific research derived from data fostered by the foundation, to Centre for Innovation and Technology Assessment in Health (NIATS), Federal University of Uberl\u00E2ndia, Brazil, and to the Federal Institute of Education, Science, and Technology Goiano (IF Goiano) \u2013 Campus Rio Verde, Campus Cristalina and the Center of Excellence in Exponential Agriculture - CEAGRE, the Goi\u00E1s State Research Support Foundation (FAPEG), for structural support to conduct this study.","Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, pp. 1809-1831, (2015); Mrozek D., Malysiak-Mrozek B., Siaznik A., Search GenBank: Interactive orchestration and ad-hoc choreography of Web services in the exploration of the biomedical resources of the national center for Biotechnology information, BMC Bioinformatics, 14, 73, (2013); Bramley R., Howe S., Marmanis H., Notes on the data quality of bibliographic records from the MEDLINE database, Database, (2023); Toaza B., Esztergar-Kiss D., Automated bibliometric data generation in python from a bibliographic database, Softw. Impacts, 19 100602, pp. 2665-9638, (2024); Oyewola D.O., Dada, Exploring machine learning: a scientometrics approach using bibliometrix and VOSviewer, SN Appl. Sci., 4, (2022); Arruda H., Silva E.R., Lessa M., Proenca D., Bartholo R., VOSviewer and bibliometrix: Resource review, J. Med. Libr. Assoc., 110, 2022, pp. 392-395, (2022); Hogue C., Ohkawa H., Bryant S., A dynamic look at structures: WWW-entrez and the molecular modeling database, Trends Biochem. Sci., 21, pp. 226-229, (1996); Ostell J., The entrez search and retrieval system, The NCBI Handbook [Internet], (2003); Pereira V., Basilio M.P., Santos C.H.T., pyBibX – a python library for bibliometric and scientometric analysis powered with artificial intelligence tools, (2023); da S. Souza L.R., da Silva D.H., Ribeiro C.T., Silva D.A., Milken P.H.B.C., Nasuto S.J., Sweeney-Reed C.M., de O. Andrade A., Pereira A.A., A bibliometric study on Parkinson's disease based on the open access data of the michael j. Fox foundation, XXIX Brazilian Congress of Biomedical Engineering, RibeirÃo Preto, Set, pp. 2-6, (2024); New API keys for the E-utilities [internet], (2017); PMID key CARLI I-share electronic resource management, (2024); da S. Souza L.R., da Silva D.H., Ribeiro C.T., Milken P.H.B.C., Nasuto S., Sweeney-Reed C.M., de O. Andrade A., Pereira A.A., A bibliometric study on Parkinson's disease based on the open access data of the michael, J. Fox Found. [ Data Set], (2024); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Inf., 11, 4, pp. 959-975, (2017); Sayers E., A general introduction to the E-utilities [updated 2022, nov 17], Entrez Programming Utilities Help [Internet], (2010)","L.R. da Silva Souza; Instituto Federal Goiano – Campus Rio Verde, Rio Verde, Brazil; email: leandro.souza@ifgoiano.edu.br","","Elsevier B.V.","","","","","","26659638","","","","English","Softw. Impacts.","Article","Final","","Scopus","2-s2.0-105004915901" -"Anwar F.; Nujen B.B.; Solli-Sæther H.","Anwar, Fahim (58863964200); Nujen, Bella B. (57023900000); Solli-Sæther, Hans (8659555000)","58863964200; 57023900000; 8659555000","Future directions of R&D internationalization in international business","2024","Multinational Business Review","32","3","","343","366","23","0","10.1108/MBR-05-2023-0081","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196556902&doi=10.1108%2fMBR-05-2023-0081&partnerID=40&md5=4412875042101b9d212f48307d93cc2b","Department of International Business, Norwegian University of Science and Technology, Ålesund, Norway","Anwar F., Department of International Business, Norwegian University of Science and Technology, Ålesund, Norway; Nujen B.B., Department of International Business, Norwegian University of Science and Technology, Ålesund, Norway; Solli-Sæther H., Department of International Business, Norwegian University of Science and Technology, Ålesund, Norway","Purpose: This paper aims to provide a focused review of international business (IB) literature on research and development (R&D) internationalization, assessing the progress and proposing future research directions. Design/methodology/approach: Total 167 peer-reviewed articles from IB journals (following the ABS list 2021 from 4* to 2) published between 1996 and 2022 are critically reviewed using a science-mapping approach. This paper used Bibliometrix R-package to analyze the retrieved bibliometric data. Additionally, a strategic diagram was developed to comprehend the maturity stage of various R&D internationalization concepts. Findings: Most studies on R&D internationalization are influenced by perspectives from advanced-economy multinational enterprises (AMNEs), while perspectives from emerging-economy multinational enterprises (EMNEs) are underrepresented. Considering the characteristics of emerging economies, firms from these locations might embark on and develop their R&D internationalization strategies differently. Investigating the emerging economy perspectives will enrich the understanding of R&D internationalization strategies for both AMNEs and EMNEs. Additionally, bringing different underutilized theoretical perspectives will help to untangle the anomalies observed in extant literature. Originality/value: This paper is among the few to scrutinize the IB literature on R&D internationalization by applying a unique combination of bibliometric techniques and a content analysis approach. By complementing existing reviews and providing fresh insights into the phenomenon, it offers a conceptual framework that can be used as a basis for further research on R&D internationalization. © 2024, Emerald Publishing Limited.","Evolutionary theory; International business; Internationalization; Multinational enterprises; Network theory; R&D internationalization","","","","","","","","Allred B.B., Swan K.S., Contextual influences on international subsidiaries' product technology strategy, Journal of International Management, 10, 2, pp. 259-286, (2004); Aparicio G., Iturralde T., Maseda A., Conceptual structure and perspectives on entrepreneurship education research: a bibliometric review, European Research on Management and Business Economics, 25, 3, (2019); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Asakawa K., Som A., Internationalization of R&D in China and India: conventional wisdom versus reality, Asia Pacific Journal of Management, 25, 3, pp. 375-394, (2008); Awate S., Larsen M.M., Mudambi R., EMNE catch-up strategies in the wind turbine industry: is there a trade-off between output and innovation capabilities?, Global Strategy Journal, 2, 3, pp. 205-223, (2012); Awate S., Larsen M.M., Mudambi R., Accessing vs sourcing knowledge: a comparative study of R&D internationalization between emerging and advanced economy firms, Journal of International Business Studies, 46, 1, pp. 63-86, (2015); Bahoo S., Alon I., Paltrinieri A., Corruption in international business: a review and research agenda, International Business Review, 29, 4, (2020); Barney J., Firm resources and sustained competitive advantage, Journal of Management, 17, 1, pp. 99-120, (1991); Belderbos R., Lokshin B., De Michiel F., R&D and foreign subsidiary performance at or below the technology frontier, Management International Review, 61, 6, pp. 745-767, (2021); Bollen J., Van De Sompel H., Hagberg A., Bettencourt L., Chute R., Rodriguez M.A., Balakireva L., Clickstream data yields high-resolution maps of science, PLoS ONE, 4, 3, (2009); Buckley P.J., Internalisation theory and outward direct investment by emerging market multinationals, Management International Review, 58, 2, pp. 195-224, (2018); Buckley P., Casson M., The Future of the Multinational Enterprise, (1976); Buckley P.J., Doh J.P., Benischke M.H., Towards a renaissance in international business research? 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Empirical evidence from Chinese subsidiaries abroad, R&D Management, 48, 2, pp. 253-265, (2018); Williamson O.E., Markets and Hierarchies: Analysis and Antitrust Implications: A Study in the Economics of Internal Organization, (1975); Williamson O.E., The Economic Institutions of Capitalism: Firms, Markets, Relational Contracting, (1985); Williamson P.J., The Global Expansion of EMNCs: Paradoxes and Directions for Future Research, (2014); Williamson P., Wan F., Emerging market multinationals and the concept of ownership advantages, International Journal of Emerging Markets, 13, 3, pp. 557-567, (2018); Zaheer S., Overcoming the liability of foreignness, Academy of Management Journal, 38, 2, pp. 341-363, (1995); Zahoor N., Khan Z., Shenkar O., International vertical alliances within the international business field: a systematic literature review and future research agenda, Journal of World Business, 58, 1, (2023); Zhao S., Papanastassiou M., Pearce R.D., Iguchi C., MNE R&D internationalization in developing Asia, Asia Pacific Journal of Management, 38, 3, pp. 789-813, (2021)","F. Anwar; Department of International Business, Norwegian University of Science and Technology, Ålesund, Norway; email: fahim.anwar@ntnu.no","","Emerald Publishing","","","","","","1525383X","","","","English","Multinational Bus. Rev.","Review","Final","","Scopus","2-s2.0-85196556902" -"Ali Abaker Omer A.; Zhang C.-H.; Liu J.; Shan Z.-G.","Ali Abaker Omer, Altyeb (57207569384); Zhang, Chun-Hua (57220546903); Liu, Jie (59542800500); Shan, Zhi-Guo (57220551119)","57207569384; 57220546903; 59542800500; 57220551119","Comprehensive review of mapping climate change impacts on tea cultivation: bibliometric and content analysis of trends, influences, adaptation strategies, and future directions","2024","Frontiers in Plant Science","15","","1542793","","","","1","10.3389/fpls.2024.1542793","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85216946620&doi=10.3389%2ffpls.2024.1542793&partnerID=40&md5=bc927e2567be5cbc205fae07be82ca87","School of Tea and Coffee, Puer University, Puer, China; Yunnan International Union Laboratory for Digital Protection and Germplasm Innovation Application of Tea Resource in China and Laos, Puer University, Puer, China","Ali Abaker Omer A., School of Tea and Coffee, Puer University, Puer, China, Yunnan International Union Laboratory for Digital Protection and Germplasm Innovation Application of Tea Resource in China and Laos, Puer University, Puer, China; Zhang C.-H., School of Tea and Coffee, Puer University, Puer, China, Yunnan International Union Laboratory for Digital Protection and Germplasm Innovation Application of Tea Resource in China and Laos, Puer University, Puer, China; Liu J., School of Tea and Coffee, Puer University, Puer, China, Yunnan International Union Laboratory for Digital Protection and Germplasm Innovation Application of Tea Resource in China and Laos, Puer University, Puer, China; Shan Z.-G., School of Tea and Coffee, Puer University, Puer, China, Yunnan International Union Laboratory for Digital Protection and Germplasm Innovation Application of Tea Resource in China and Laos, Puer University, Puer, China","Climate change has a profound impact on tea cultivation, posing significant challenges to yield, quality, and sustainability due to stressors such as drought, temperature fluctuations, and elevated CO₂ levels. This study aims to address these challenges by identifying and synthesizing key themes, influential contributions, and effective adaptation strategies for mitigating the impacts of climate change on tea production. A systematic bibliometric and content analysis was conducted on 328 peer-reviewed documents (2004–2023), following the PRISMA methodology. Performance analysis using Bibliometrix examined trends in publication output, leading contributors, and geographical distribution, while science mapping with VOSviewer revealed collaboration networks and thematic clusters. A detailed review of highly cited studies highlighted the primary climate variables affecting tea cultivation and identified innovative adaptation strategies, as well as critical knowledge gaps. The results show significant progress in understanding the physiological, biochemical, and molecular responses of tea plants to climate-induced stressors, including antioxidant mechanisms, secondary metabolite regulation, and genomic adaptations. Despite these advancements, challenges remain, particularly regarding the combined effects of multiple stressors, long-term adaptation strategies, and the socioeconomic implications of climate change. The findings underscore the need for interdisciplinary approaches that integrate molecular, ecological, and socioeconomic research to address these issues. This study provides a solid foundation for guiding future research, fostering innovative adaptation strategies, and informing policy interventions to ensure sustainable tea production in a changing climate. Copyright © 2025 Ali Abaker Omer, Zhang, Liu and Shan.","adaptation strategies; antioxidants; climate change; secondary metabolites; socioeconomic impacts; sustainability; tea cultivation; tea quality","","","","","","Pu’er Tea Processing Engineering Research Center; Pu’er Tea Processing Engineering Research Center of Yunnan Provincial Universities; Key Scientific Research Special Planning Project of Pu’er University, (2020XJGH08, 2020XGH08); National Natural Science Foundation of China, NSFC, (32360771); National Natural Science Foundation of China, NSFC; Tea and Coffee, (KY202311); Science and Technology Program of Yunnan Provincial Department of Science and Technology, (202101BA070001-239); Pu’er College Top Notch Innovation Team, (2023PEXYCXTD00l, 2023YLKCZX005, 2023YLKCZX004); Yunnan Ministry of Education Project, (2024]1099); Ministry of Higher Education and Scientific Research, MOHESR, (2024J1099); Ministry of Higher Education and Scientific Research, MOHESR; Pu’er Tea Science and Technology R&D and Innovation Team, (CXTD020)","Funding text 1: The authors thank Pu\u2019er University, China, and the Yunnan International Union Laboratory for Digital Protection and Germplasm Innovation Application of Tea Resource in China and Laos for their invaluable institutional support. Special thanks are extended to the National Natural Science Foundation of China (Grant No. 32360771) and the Science and Technology Program of Yunnan Provincial Department of Science and Technology (Grant No. 202101BA070001-239) for their generous financial support, which was instrumental in conducting this research. We also sincerely thank the Pu\u2019er Tea Processing Engineering Research Center and the Key Scientific Research Special Planning Project of Pu\u2019er University (Grant No. 2020XJGH08) for providing essential resources and technical support. The constructive feedback and encouragement from our colleagues at the Pu\u2019er College Top-notch Innovation Team and the Yunnan Ministry of Education (Grant No. 2024J1099) have significantly enriched this work. Finally, we acknowledge the invaluable contribution of the reviewers and editors for their constructive comments, which have greatly improved the quality of this manuscript. This research would not have been possible without everyone\u2019s involvement collective efforts and collaboration. ; Funding text 2: The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This research was supported by the Development and Research of Hybrid Photovoltaic based on National Natural Science Foundation of China (32360771), the Science and Technology Program of Yunnan Provincial Department of Science and Technology (202101BA070001-239), the Pu\u2019er Tea Processing Engineering Research Center of Yunnan Provincial Universities, the Key Scientific Research Special Planning Project of Pu\u2019er University (2020XGH08), the Pu\u2019er Tea Science and Technology R&D and Innovation Team (CXTD020), the Pu\u2019er College Top Notch Innovation Team (2023PEXYCXTD00l), the First-class Undergraduate Course (2023YLKCZX004, 2023YLKCZX005), and the Yunnan Ministry of Education Project (2024]1099), \u201CTea and Coffee\u201D Crops in Pu\u2019er City under grant No. KY202311. 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Kuntze), Scientia Hortic, 285, (2021); Zhang Q., Cai M., Yu X., Wang L., Guo C., Ming R., Et al., Transcriptome dynamics of Camellia sinensis in response to continuous salinity and drought stress, Tree Genet. Genomes, 13, (2017); Zhao C., Nawaz G., Cao Q., Xu T., Melatonin is a potential target for improving horticultural crop resistance to abiotic stress, Scientia Hortic, 291, (2022); Zheng C., Wang Y., Ding Z., Zhao L., Global transcriptional analysis reveals the complex relationship between tea quality, leaf senescence and the responses to cold-drought combined stress in Camellia sinensis, Front. Plant Sci, 7, (2016); Zhou L., Xu H., Mischke S., Meinhardt L.W., Zhang D., Zhu X., Et al., Exogenous abscisic acid significantly affects proteome in tea plant (Camellia sinensis) exposed to drought stress, Horticulture Res, 1, (2014); Zou Y., Hirono Y., Yanai Y., Hattori S., Toyoda S., Yoshida N., Isotopomer analysis of nitrous oxide accumulated in soil cultivated with tea (Camellia sinensis) in Shizuoka, central Japan, Soil Biol. Biochem, 77, pp. 276-291, (2014)","A. Ali Abaker Omer; School of Tea and Coffee, Puer University, Puer, China; email: altyebali@peu.edu.cn; Z.-G. Shan; School of Tea and Coffee, Puer University, Puer, China; email: altyebali@peu.edu.cn","","Frontiers Media SA","","","","","","1664462X","","","","English","Front. Plant Sci.","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85216946620" -"Kang J.; Jiang N.; Shataer M.; Tuersong T.","Kang, Jiawei (59156773500); Jiang, Nan (59481605100); Shataer, Munire (57219713238); Tuersong, Tayier (57208920142)","59156773500; 59481605100; 57219713238; 57208920142","Corrigendum: Research progress of breast cancer surgery during 2010–2024: a bibliometric analysis (Frontiers in Oncology, (2024), 14, (1508568), 10.3389/fonc.2024.1508568)","2025","Frontiers in Oncology","15","","1550434","","","","0","10.3389/fonc.2025.1550434","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85217839475&doi=10.3389%2ffonc.2025.1550434&partnerID=40&md5=43dabb90a9a953a7c324161f7e922c41","Department of Clinical Medicine, Xinjiang Medical University, Xinjiang, Ürümqi, China; Department of Histology and Embryology, Basic Medical College of Xinjiang Medical University, Xinjiang, Ürümqi, China; Department of Pharmacy, Xinjiang Key Laboratory of Neurological Diseases, Xinjiang Clinical Research Center for Nervous System Diseases, Second Affiliated Hospital of Xinjiang Medical University, Xinjiang, Ürümqi, China","Kang J., Department of Clinical Medicine, Xinjiang Medical University, Xinjiang, Ürümqi, China; Jiang N., Department of Clinical Medicine, Xinjiang Medical University, Xinjiang, Ürümqi, China; Shataer M., Department of Histology and Embryology, Basic Medical College of Xinjiang Medical University, Xinjiang, Ürümqi, China; Tuersong T., Department of Pharmacy, Xinjiang Key Laboratory of Neurological Diseases, Xinjiang Clinical Research Center for Nervous System Diseases, Second Affiliated Hospital of Xinjiang Medical University, Xinjiang, Ürümqi, China","In the published article, the reference for 14 was incorrectly written as “van Eck NJ, Waltman L. Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics. (2010) 84:523–38. doi: 10.1007/s11192-009-0146-3”. It should be “Ogunsakin RE, Ebenezer O, Ginindza TG. A bibliometric analysis of the literature on Norovirus disease from 1991-2021. Int J Environ Res Public Health. (2022) 19(5):2508. doi: 10.3390/ijerph19052508”. In the published article, the reference for 15 was incorrectly written as “Waltman L, van Eck NJ. A new methodology for constructing a publication-level classification system of science. J Assoc Inf Sci Technol. (2012) 63:2378–92. doi: 10.1002/asi.22693”. It should be “Musa HH, Musa TH. A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus database. Hum Vaccin Immunother. (2022) 18(6):2135927. doi: 10.1080/21645515.2022.2135927”. In the published article, the reference for 16 was incorrectly written as “Chen C. Science mapping: A systematic review of the literature. J Data Inf Sci.(2017) 2:1–40. doi: 10.1515/jdis-2017-0006]”. It should be “Volpe S, Mastroleo F, Krengli M, Jereczek-Fossa BA. Quo vadis radiomics? Bibliometric analysis of 10-year Radiomics journey. Eur Radiol. (2023) 33(10):6736–45. doi: 10.1007/s00330-023-09645-6”. In the published article, there was an error. The method description was inaccurate. A correction has been made to Abstract, Methods, Paragraph 1. This sentence previously stated: “Employing the “bibliometrix” package in the R programming language, alongside VOSviewer and CiteSpace software” The corrected sentence appears below: “Employing the “bibliometrix” package in the R software” A correction has been made to Abstract, Methods, Paragraph 1. This sentence previously stated: “The analysis encompassed publication trends, collaborative networks, journal evaluation, author and institutional assessments, country-specific analyses, keyword exploration, and the identification of research hotspots.” The corrected sentence appears below: “The analysis encompassed publication trends, collaborative networks, co-citation networks, co-occurrence networks, journal evaluation, prominent publications, author and institutional assessments, country-specific analyses, keyword exploration, and the identification of research hotspots.” In the published article, there was an error. A correction has been made to Methods, 2.2 Data analysis, Paragraph 1. This sentence previously stated: “We conducted a bibliometric analysis of the collected data using the”bibliometrix” package in R (version 4.3.1, http://www.bibliometrix.org) (13). This package enabled the extraction of critical information and the construction of co-occurrence networks encompassing countries, institutions, journals, and authors. Furthermore, it facilitated thematic evolution analysis and the development of a global publication distribution network. In addition, VOSviewer software was employed for the visualization of collaboration and coword networks (14, 15). CiteSpace (version 5.8.R2) was employed to analyze keyword co-occurrence and citation networks, revealing research trends and knowledge structures (16).” The corrected sentence appears below: “The content should be changed to the following: This study predominantly utilizes the R package “bibliometrix” (version 4.2.3) (13) (accessible at https://www.bibliometrix.org) for conducting bibliometric analysis. Data analysis is performed using R code in conjunction with the Bibliometrix package (R version 4.2.0) (14)(15). The initial data interpretation is facilitated through the “biblioAnalysis()” command and the “summary()” function within the Bibliometrix package (16). Collaboration networks are examined using the “metaTagExtraction” and “Biblionetwork” commands, with subsequent graphical representation achieved via the “Networkplot” command. Furthermore, the “Biblioshiny()” command is employed for analyses pertaining to national scientific collaboration, institutional collaboration networks, keyword analysis, co-occurrence network synthesis, and thematic map analysis.” A correction has been made to Results, 3.13 Analysis of trend themes and topic mapping, Paragraph 1. This sentence previously stated: “To address the analytical inconsistencies observed across various software tools, we employed the Bibliomtrix software package to more accurately identify research hotspots within the field” The corrected sentence appears below: “We employed the “bibliomtrix” software package to more accurately identify research hotspots within the field” A correction has been made to Discussion, 4.1 Research status, Paragraph 1. This sentence previously stated: “This study employed software tools including R language, CiteSpace, and VOSviewer to perform a comprehensive visual analysis of 1,195 scholarly articles related to BC surgery” The corrected sentence appears below: “This study employed “bibliometrix” package to perform a comprehensive visual analysis of 1,195 scholarly articles related to BC surgery” A correction has been made to Discussion, 4.8 Limitations, Paragraph 1. This sentence previously stated: “the analysis may exhibit a bias toward mastectomy or lumpectomy, potentially neglecting other critical dimensions of BC surgery, such as reconstructive procedures and the psychological ramifications of surgical choices on patients. This narrow focus may limit the applicability of the study’s findings to the wider context of BC treatment.” The corrected sentence appears below: “this study sought to incorporate literature of high relevance to BC surgery to enhance the credibility of the research findings. However, this focus may have resulted in the exclusion of other pertinent literature related to BC surgery. We recognize this limitation and commit to examining a more comprehensive array of literature in future research endeavors.” A correction has been made to Conclusion, Paragraph 1. This sentence previously stated: “This study utilized bibliometric tools such as R language, CiteSpace, and VOSviewer for a visual analysis of literature on BC surgery.” The corrected sentence appears below: “This study utilized “bibliometrix” package for a visual analysis of literature on BC surgery.” The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated. Copyright © 2025 Kang, Jiang, Shataer and Tuersong.","bibliometric analysis; breast cancer surgery; international collaboration; publication patterns; research hotspots","drug therapy; erratum; human","","","","","","","","T. Tuersong; Department of Pharmacy, Xinjiang Key Laboratory of Neurological Diseases, Xinjiang Clinical Research Center for Nervous System Diseases, Second Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang, China; email: tayiertuersong@163.com","","Frontiers Media SA","","","","","","2234943X","","","","English","Front. Oncol.","Erratum","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85217839475" -"Kumar D.; Shandilya A.K.; Kumar N.","Kumar, Dilip (59116291900); Shandilya, Abhinav Kumar (58079894200); Kumar, Nishikant (59926148900)","59116291900; 58079894200; 59926148900","Comprehending the multifaceted realm of blockchain within the hotel industry: Science mapping approach","2024","Hotel and Travel Management in the AI Era","","","","203","218","15","0","10.4018/979-8-3693-7898-4.ch010","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105007124874&doi=10.4018%2f979-8-3693-7898-4.ch010&partnerID=40&md5=a7a78c8f8208b680f2066bada023dd51","Manipal Academy of Higher Education, India; Birla Institute of Technology, India","Kumar D., Manipal Academy of Higher Education, India; Shandilya A.K., Birla Institute of Technology, India; Kumar N., Birla Institute of Technology, India","To identify the performance pattern, keyword cluster appearance and thematic development of blockchain adoption in the hotel industry from the literature published in the Scopus database since 2018. The PRISMA pattern was followed for the inclusion and exclusion of data. The data was extracted from the Scopus database since 2018. Initially, 93 data appeared in the search and after refining the dataset bibliometric analysis was performed for 48 documents. Bibliometrix (Biblioshiny), an openaccess software, was used to analyse the data. The keyword clusters that appeared are ""Luxury augmented experiences"", ""Experiential hospitality"", ""Decentralised hospitality solutions"", and ""Secure AI ecosystem"". Bibliographic coupling analysis (BCA) generated four major themes - ""Impact of technologies in hospitality and tourism"", ""Technological transformation in hotels"", ""Bitcoin and blockchain in hotels"", and ""Security solutions and blockchain"". The adoption of blockchain technology can play a pivotal role in achieving the Sustainable Development Goals - 9. © 2024, IGI Global.","","Bibliographic retrieval systems; Bibliographic couplings; Bibliometrics analysis; Block-chain; Coupling analysis; Decentralised; Hotel industry; Inclusion and exclusions; OpenAccess; Performance patterns; Scopus database; Mapping","","","","","","","Aggarwal S., Kumar N., History of blockchain-Blockchain 1.0: Currency, In Advances in Computers, pp. 147-169, (2021); Ahmad A.N., Samsudin N., Blockchain Technology in Aviation, Tourism, and Hospitality, In Hassan, A. and Abdul Rahman, N. 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Marques and R.P. Marques (eds) Digital Transformation of the Hotel Industry. Cham: Springer International Publishing, (2023); Gangwar V.P., Reddy D., Hospitality Industry 5.0: Emerging Trends in Guest Perception and Experiences, Advances in Business Strategy and Competitive Advantage, pp. 185-211, (2023); Hole Y., Blockchain Usages In Hospitality Management, 2023 3rd International Conference on Advance Computing and Innovative Technologies in Engineering (ICACITE). IEEE, (2023); Hsieh M.Y., Weng T.H., Wang P.W., Kao C.H., Recommendation service for hotel applications on blockchain, International Journal on Computer Science and Engineering, 25, 6, (2022); A Blockchain Model in the Hospitality Industry to Increase Traceability and Transparency of Transactions, 2023 International Seminar on Application for Technology of Information and Communication (iSemantic) 2023. International Seminar on Application for Technology of Information and Communication (iSemantic), (2023); Jain P., Singh R.K., Mishra R., Rana N.P., Emerging dimensions of blockchain application in tourism and hospitality sector: A systematic literature review, Journal of Hospitality Marketing & Management, 32, 4, pp. 454-476, (2023); Kraus S., Breier M., Dasi-Rodriguez S., The art of crafting a systematic literature review in entrepreneurship research, The International Entrepreneurship and Management Journal, 16, 3, pp. 1023-1042, (2020); Maseda A., Iturralde T., Cooper S., Aparicio G., Mapping women's involvement in family firms: A review based on bibliographic coupling analysis, International Journal of Management Reviews, 24, 2, pp. 279-305, (2022); Moyeenudin H.M., Detecting Device Sensors of Luxury Hotels using Blockchain-based Federated Learning to Increase Customer Satisfaction, In Krishnan, S. et al., Handbook on Federated Learning (1st ed.), pp. 283-307, (2023); Ozgit H., Adalier A., Can Blockchain technology help small islands achieve sustainable tourism? A perspective on North Cyprus, Worldwide Hospitality and Tourism Themes, 14, 4, pp. 374-383, (2022); Page M.J., The PRISMA 2020 statement: an updated guideline for reporting systematic reviews, BMJ, (2021); Paktiti M., Economides A.A., Smart contract applications in tourism, International Journal of Technology Management & Sustainable Development, 22, 2, pp. 165-184, (2023); Parameswaran G., Accommodation Finder: An Augmented Reality Based Mobile Application Integrated with Smart Contracts, 2021 3rd International Conference on Advancements in Computing (ICAC) 2021 3rd International Conference. on Advancements in Computing (ICAC), (2021); Ramos C.M.Q., Blockchain Technology in Tourism Management: Potentialities, Challenges, and Implications, Advances in Marketing, Customer Relationship Management, and E-Services, (2021); Saraf K., Bajar K., Jain A., Barve A., Assessment of barriers impeding the incorporation of blockchain technology in the service sector: A case of hotel and health care, Journal of Modelling in Management, 19, 2, pp. 407-440, (2024); Shrestha A.K., Vassileva J., Deters R., A Blockchain Platform for User Data Sharing Ensuring User Control and Incentives, Frontiers in Blockchain, 3, (2020); Strebinger A., Treiblmaier H., Profiling early adopters of blockchain-based hotel booking applications: Demographic, psychographic, and service-related factors, Information Technology & Tourism, 24, 1, pp. 1-30, (2022); Verma A., Shukla V.K., Sharma R., Convergence of IOT in Tourism Industry: A Pragmatic Analysis, Journal of Physics: Conference Series, 1714, 1, (2021); Willie P., Can all sectors of the hospitality and tourism industry be influenced by the innovation of Blockchain technology?, Worldwide Hospitality and Tourism Themes, 11, 2, pp. 112-120, (2019); Yadav S., Distributed Hotel Chain Using Blockchain and Chainlink, R.N. Shaw, M. Paprzycki, and A. Ghosh (eds) Advanced Communication and Intelligent Systems. Cham: Springer Nature Switzerland, (2023); Zeren S.K., Revolutionizing Tourism Payments, Blockchain for Tourism and Hospitality Industrie, pp. 66-83, (2023); Zhang L., Hang L., Jin W., Kim D., Interoperable Multi-Blockchain Platform Based on Integrated REST APIs for Reliable Tourism Management, Electronics (Basel), 10, 23, (2021)","","","IGI Global","","","","","","","979-836937900-4; 979-836937898-4","","","English","Hotel and Travel Manag. in the AI Era","Book chapter","Final","","Scopus","2-s2.0-105007124874" -"Jiang Y.; Cai Y.; Zhang X.; Chen L.; Zhou X.; Chen Y.","Jiang, Yaping (56849605800); Cai, Yuying (57219281779); Zhang, Xin (57220094770); Chen, Li (57192611322); Zhou, Xingtao (7410090610); Chen, Yihui (7601424783)","56849605800; 57219281779; 57220094770; 57192611322; 7410090610; 7601424783","A Two-Decade Bibliometric Analysis of Laser in Ophthalmology: From Past to Present","2024","Clinical Ophthalmology","18","","","1313","1328","15","2","10.2147/OPTH.S458840","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85194175271&doi=10.2147%2fOPTH.S458840&partnerID=40&md5=a1cd86b8bfc628b05ddcfcc46e295414","Department of Ophthalmology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China; Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University, NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China","Jiang Y., Department of Ophthalmology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China; Cai Y., Department of Ophthalmology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China; Zhang X., Department of Ophthalmology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China; Chen L., Department of Ophthalmology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China; Zhou X., Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University, NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China; Chen Y., Department of Ophthalmology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China","Background: Laser therapy has been proven as an effective technique for managing ophthalmological disorders. To guide future research, we conducted a bibliometric analysis of laser applications in eye diseases from 1990 to 2022, aiming to identify key themes and trends. Methods: We retrieved 3027 publications from the Web of Science Core Collection (WoSCC). Bibliometrix was used for science mapping of the literature, while VOSviewer and CiteSpace were applied to visualize co-authorship, co-citation, co-occurrence, and bibliographic coupling networks. Results: From a co-citation reference network, we identified 52 distinct clusters. Our analysis uncovered three main research trends. The first trend revolves around the potential evolution of corneal laser surgery techniques, shifting from the treatment of refractive errors to broader applications in biomedical optics. The second trend illustrates the advancement of laser applications in treating a range of disorders, from retinal and ocular surface diseases to glaucoma. The third trend focuses on the innovative uses of established technologies. Conclusion: This study offers significant insights into the evolution of laser applications in ophthalmology over the past 30 years, which will undoubtedly assist scientists in directing further research in this promising field. © 2024 Jiang et al. This work is published and licensed by Dove Medical Press Limited.","bibliometric; CiteSpace; laser; research trend; systematic review","bibliometrics; cataract; eye disease; glaucoma; human; laser coagulation; laser refractive surgery; laser surgery; network analysis; ophthalmology; photorefractive keratectomy; refraction error; retina detachment; Review; systematic review","","","","","National Natural Science Foundation of China, NSFC, (82271050, 82301175); National Natural Science Foundation of China, NSFC; Science and Technology Commission of Shanghai Municipality, STCSM, (22YF1443100); Science and Technology Commission of Shanghai Municipality, STCSM","This work was funded by the National Natural Science Foundation of China to YHC (82271050) and YPJ (82301175). The Yangfan Plan of Shanghai Science and Technology Commission to YPJ (22YF1443100).","McGuff PE, Deterling RA, Gottlieb LS, Fahimi HD, Bushnell D., Surgical applications of laser, Ann Surg, 160, 4, pp. 765-777, (1964); Patz A, Fine S, Finkelstein D., Photocoagulation treatment of proliferative diabetic retinopathy: the second report of diabetic retinopathy study findings, Ophthalmology, 85, 1, pp. 82-106, (1978); Photocoagulation for diabetic macular edema. 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A pilot study, Arch Ophthalmol, 97, 2, pp. 319-322, (1979); Latina MA, Park C., Selective targeting of trabecular meshwork cells: in vitro studies of pulsed and CW laser interactions, Exp Eye Res, 60, 4, pp. 359-371, (1995); Fea AM, Bosone A, Rolle T, Brogliatti B, Grignolo FM., Micropulse diode laser trabeculoplasty (MDLT): a phase II clinical study with 12 months follow-up, Clin Ophthalmol, 2, 2, pp. 247-252, (2008); Francis BA, Kawji AS, Vo NT, Dustin L, Chopra V., Endoscopic cyclophotocoagulation (ECP) in the management of uncontrolled glaucoma with prior aqueous tube shunt, J Glaucoma, 20, 8, pp. 523-527, (2011); Sun X, Liang YB, Wang NL, Et al., Laser peripheral iridotomy with and without iridoplasty for primary angle-closure glaucoma: 1-year results of a randomized pilot study, Am J Ophthalmol, 150, 1, pp. 68-73, (2010); Ollikainen ML, Puustjarvi TJ, Rekonen PK, Uusitalo HM, Terasvirta ME., Mitomycin C-augmented deep sclerectomy in primary open-angle glaucoma and exfoliation glaucoma: a three-year prospective study, Acta Ophthalmol, 89, 6, pp. 548-555, (2011); Popovic M, Campos-Moller X, Schlenker MB, Ahmed II., Efficacy and safety of femtosecond laser-assisted cataract surgery compared with manual cataract surgery: a meta-analysis of 14 567 eyes, Ophthalmology, 123, 10, pp. 2113-2126, (2016); Grewal DS, Schultz T, Basti S, Dick HB., Femtosecond laser-assisted cataract surgery--current status and future directions, Surv Ophthalmol, 61, 2, pp. 103-131, (2016); Nakagawa S, Samarasinghe G, Haddaway NR, Et al., Research weaving: visualizing the future of research synthesis, Trends Ecol Evol, 34, 3, pp. 224-238, (2019); Janssens AC, Gwinn M., Novel citation-based search method for scientific literature: application to meta-analyses, BMC Med Res Methodol, 15, 1, (2015); Synnestvedt MB, Chen C, Holmes JH., CiteSpace II: visualization and knowledge discovery in bibliographic databases, AMIA Annu Symp Proc, 2005, pp. 724-728, (2005); Sweileh WM., Global research trends of World Health Organization’s top eight emerging pathogens, Global Health, 13, 1, (2017); Urlings MJE, Duyx B, Swaen GMH, Bouter LM, Zeegers MP., Citation bias and other determinants of citation in biomedical research: findings from six citation networks, J Clin Epidemiol, 132, pp. 71-78, (2021); Thornton A, Lee P., Publication bias in meta-analysis: its causes and consequences, J Clin Epidemiol, 53, 2, pp. 207-216, (2000)","X. Zhou; Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University, NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, No. 19 Baoqing Road, Xuhui District, 200031, China; email: doctzhouxingtao@163.com; Y. Chen; Department of Ophthalmology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, 450 Tengyue Road, 200090, China; email: 1300089@tongji.edu.cn","","Dove Medical Press Ltd","","","","","","11775467","","","","English","Clin. Ophthalmol.","Review","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85194175271" -"Pant K.; Palanisamy P.","Pant, Kamlesh (57206305021); Palanisamy, Parthiban (59125384100)","57206305021; 59125384100","Industry 4.0 in the Perspective of Supply Chain Management: Evolution and Future Research Agenda","2025","EMJ - Engineering Management Journal","37","1","","52","70","18","2","10.1080/10429247.2024.2350287","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105001993639&doi=10.1080%2f10429247.2024.2350287&partnerID=40&md5=e84fd736f03d611eb63cfc16e2a34392","National Institute of Technology, India","Pant K., National Institute of Technology, India; Palanisamy P., National Institute of Technology, India","With the rise of Industry 4.0 (I4.0), there has been a shift from traditional to digital ways of running businesses by bringing the real and virtual worlds together. This study examines I4.0 literature in Supply chain management (SCM) over the last five years, finds essential research areas and gaps, and suggests a roadmap of new possibilities and opportunities for further research. First, a performance analysis was undertaken in which the most relevant or productive authors, leading journals, and top countries were examined. Second, a science mapping analysis involving citation, co-citation, and keyword analysis was conducted. Third, a thematic analysis was performed in which numerous themes were discussed in the direction of I4.0 in SCM. The authors examined 260 research publications published during the last five years. The authors used the R package bibliometrix, biblioshiny application, and the Vosviewer to visualize the structure of over 19,000 different references. Finally, the paper suggests a framework for implementing I4.0 in the supply chain (SC). The outcome of this study will help academic scholars, industry practitioners and engineering managers to identify significant themes and areas and implement I4.0 standards in SCM. © 2024 American Society for Engineering Management.","Industry 4.0; performance analysis; science mapping analysis; supply chain management; thematic analysis","Industry 4.0; Mapping; Virtual reality; Mapping analysis; Performances analysis; Real-world; Research agenda; Research areas; Research gaps; Roadmap; Science mapping analyse; Thematic analysis; Virtual worlds; Supply chain management","","","","","","","Abdel-Basset M., Manogaran G., Mohamed M., Internet of things (IoT) and its impact on supply chain: A framework for building smart, secure and efficient systems, Future Generation Computer Systems, 86, pp. 614-628, (2018); Abdirad M., Krishnan K., Industry 4.0 in logistics and supply chain management: A systematic literature review, EMJ - Engineering Management Journal, 33, 3, pp. 1-15, (2020); Adebanjo D., Laosirihongthong T., Samaranayake P., Teh P.L., Key enablers of industry 4.0 development at firm level: Findings from an emerging economy, IEEE Transactions on Engineering Management, 70, 2, pp. 400-416, (2021); Ali I., Arslan A., Khan Z., Tarba S.Y., The role of industry 4.0 technologies in mitigating supply chain disruption: Empirical evidence from the Australian food processing industry, IEEE Transactions on Engineering Management, (2021); Appio F.P., Cesaroni F., DiMinin A., Visualizing the structure and bridges of the intellectual property management and strategy literature: A document co-citation analysis, Scientometrics, 101, 1, pp. 623-661, (2014); Ardito L., Petruzzelli A.M., Panniello U., Garavelli A.C., Towards industry 4.0: Mapping digital technologies for supply chain management-marketing integration, Business Process Management Journal, 25, 2, pp. 323-346, (2019); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aria M., Misuraca M., Spano M., Mapping the evolution of social research and data science on 30 years of social indicators research, Social Indicators Research, 149, 3, pp. 803-831, (2020); Arora S., Majumdar A., Machine learning and soft computing applications in textile and clothing supply chain: Bibliometric and network analyses to delineate future research agenda, Expert Systems with Applications, 200, June 2021, (2022); Case studies the paradox of smart manufacturing, (2018); Baker H.K., Kumar S., Pandey N., Forty years of the journal of futures markets: A bibliometric overview, Journal of Futures Markets, 41, 7, pp. 1027-1054, (2021); Barata J., Rupino Da Cunha P., Stal J., Mobile supply chain management in the industry 4.0 era: An annotated bibliography and guide for future research, Journal of Enterprise Information Management, 31, 1, pp. 173-192, (2018); Barreto L., Amaral A., Pereira T., ScienceDirect ScienceDirect ScienceDirect ScienceDirect in conference logistics: Costing models for capacity optimization in industry trade-off between used capacity and operational efficiency, Procedia Manufacturing, 13, pp. 1245-1252, (2017); Beatriz A., De Sousa L., Jose C., Jabbour C., Foropon C., Echnological forecasting & social change when titans meet–can industry 4. 0 revolutionise the environmentally- sustainable manufacturing wave? The role of critical success factors, Technological Forecasting & Social Change, (2018); Belhadi A., Kamble S., Jabbour C.J.C., Gunasekaran A., Ndubisi N.O., Venkatesh M., Manufacturing and service supply chain resilience to the COVID-19 outbreak: Lessons learned from the automobile and airline industries, Technological Forecasting and Social Change, 163, (2021); Ben-Daya M., Hassini E., Bahroun Z., Internet of things and supply chain management: A literature review, International Journal of Production Research, 57, 15-16, pp. 4719-4742, (2019); Bhat T.P., India and industry 4.0. A paper prepared as part of the research programme industrial, trade and investment policies: Pathways to industrialization, (2020); Bienhaus F., Haddud A., Procurement 4.0: Factors influencing the digitisation of procurement and supply chains, Business Process Management Journal, 24, 4, pp. 965-984, (2018); Blackburn S., Galvin J., Laberge L., Williams E., Strategy for a digital world a winning digital strategy requires new twists to familiar moves, McKinsey Quarterly (Issue October), (2021); Bodkhe U., Tanwar S., Parekh K., Khanpara P., Tyagi S., Kumar N., Alazab M., Blockchain for industry 4.0: A comprehensive review, Institute of Electrical and Electronics Engineers Access, 4, pp. 79764-79800, (2020); Bradford S.C., Sources of information on specific subjects, Engineering, 137, pp. 85-86, (1934); Brettel M., Friederichsen N., Keller M., Rosenberg M., How virtualization, decentralization and network building change the manufacturing landscape: An industry 4.0 perspective, FormaMente, 12, (2017); 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Palanisamy; Department of Production Engineering, National Institute of Technology, Tiruchirappalli, Tamil Nadu, 620015, India; email: parthee_p@yahoo.com","","Taylor and Francis Ltd.","","","","","","10429247","","EMJOE","","English","EMJ Eng Manage J","Article","Final","","Scopus","2-s2.0-105001993639" -"Singh A.P.; Behera R.K.; Bala P.K.","Singh, Amrit Pal (59236547200); Behera, Rajat Kumar (57200944520); Bala, Pradip Kumar (26639138400)","59236547200; 57200944520; 26639138400","Evolution of sustainable retailing and how it influences consumer behavior: a bibliometric review","2025","International Review of Retail, Distribution and Consumer Research","35","3","","260","290","30","3","10.1080/09593969.2024.2381066","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199788644&doi=10.1080%2f09593969.2024.2381066&partnerID=40&md5=3d3225bca4c1abe051261b1b4eb16a4d","Information Systems & Business Analytics, Indian Institute of Management, Ranchi, India; School of Computer Engineering, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar, India","Singh A.P., Information Systems & Business Analytics, Indian Institute of Management, Ranchi, India; Behera R.K., School of Computer Engineering, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar, India; Bala P.K., Information Systems & Business Analytics, Indian Institute of Management, Ranchi, India","Over the years, sustainability has garnered much attention owing to evidence of climate change, United Nations (UN) sustainable development goals, pandemics, and the changing behavior of millennials. Retailers are one of the largest consumers of global natural and human resources. They have joined the sustainability bandwagon by pledging resources and communicating the same to their target customers for better business positioning. This study aims to analyze the conceptual structure of sustainability in the context of retail enterprises and its role in shaping consumer behavior. Therefore, it leverages bibliometric techniques to elaborate on the productivity and impact of the existing body of knowledge in this area through performance analysis and discover the knowledge clusters through science mapping. The data used for this study were sourced by querying the Scopus database for the intersection of terms related to ‘sustainability,’ ‘retail,’ and ‘consumer behavior.’ Subsequently, they were processed and illustrated using RStudio and the bibliometrix package for R to drive insights in bibliometric summaries, including tables, maps, and networks. In addition to highlighting temporal and spatial trends and dominant themes, the study suggests future research avenues in sustainable retailing. © 2024 Informa UK Limited, trading as Taylor & Francis Group.","bibliometric; consumer behavior; Retail; science mapping; sustainability","","","","","","","","Acosta Salgado L., Morel L., Verilhac I., Towards a Better Understanding of the Concept of Design, Projectics / Proyéctica / Projectique, 20, 2, pp. 91-114, (2019); Aibar-Guzman B., Garcia-Sanchez I.-M., Aibar-Guzman C., Hussain N., Sustainable Product Innovation in Agri-Food Industry: Do Ownership Structure and Capital Structure Matter?, Journal of Innovation & Knowledge, 7, 1, (2022); Ajzen I., The Theory of Planned Behavior, Organizational Behavior and Human Decision Processes, 50, 2, pp. 179-211, (1991); Al-Tohamy R., Ali S.S., Zhang M., Elsamahy T., Abdelkarim E.A., Jiao H., Sun S., Sun J., Environmental and Human Health Impact of Disposable Face Masks During the COVID-19 Pandemic: Wood-Feeding Termites As a Model for Plastic Biodegradation, Applied Biochemistry and Biotechnology, 195, 3, pp. 2093-2113, (2023); Aria M., Cuccurullo C., Bibliometrix: An R-Tool for Comprehensive Science Mapping Analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Armstrong C.M., Niinimaki K., Kujala S., Karell E., Lang C., Sustainable Product-Service Systems for Clothing: Exploring Consumer Perceptions of Consumption Alternatives in Finland, Journal of Cleaner Production, 97, pp. 30-39, (2015); Arruda-Filho E.J.M., Lennon M.M., How iPhone Innovators Changed Their Consumption in iDay2: Hedonic Post or Brand Devotion, International Journal of Information Management, 31, 6, pp. 524-532, (2011); Aschemann-Witzel J., de Hooge I., Amani P., Bech-Larsen T., Oostindjer M., Consumer-Related Food Waste: Causes and Potential for Action, Sustainability, 7, 6, pp. 6457-6477, (2015); Badr A.A., Hassanin A., Moursey M., Influence of Tencel/Cotton Blends on Knitted Fabric Performance, Alexandria Engineering Journal, 55, 3, pp. 2439-2447, (2016); Bauer J.M., Aarestrup S.C., Hansen P.G., Reisch L.A., Nudging More Sustainable Grocery Purchases: Behavioural Innovations in a Supermarket Setting, Technological Forecasting & Social Change, 179, (2022); Biermann F., Kanie N., Kim R.E., Global Governance by Goal-Setting: The Novel Approach of the UN Sustainable Development Goals, Current Opinion in Environmental Sustainability, 26-27, pp. 26-31, (2017); Biswas D., Jalali H., Ansaripoor A.H., de Giovanni P., Traceability Vs. 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How Useful Are Bibliometric Indices for the Evaluation of Scientific Quality or Scientific productivity? Annals of Anatomy, Anatomischer Anzeiger, 193, 3, pp. 191-196, (2011); Williams A., Hodges N., Adolescent Generation Z and Sustainable and Responsible Fashion Consumption: Exploring the Value-Action Gap, Young Consumers, 23, 4, pp. 651-666, (2022); Wu M., Ran Y., Zhu S.X., Optimal Pricing Strategy: How to Sell to Strategic Consumers?, International Journal of Production Economics, 244, (2022); Xiao J., Yang Z., Li Z., Chen Z., A Review of Social Roles in Green Consumer Behaviour, International Journal of Consumer Studies, 47, 6, pp. 2033-2070, (2022); Xu J., Zhou Y., Jiang L., Shen L., Exploring Sustainable Fashion Consumption Behavior in the Post-Pandemic Era: Changes in the Antecedents of Second-Hand Clothing-Sharing in China, Sustainability, 14, 15, (2022); Zaki H.O., Fernandez D., Dastane O., Aman A., Sanusi S., Virtual Reality in Digital Marketing: Research Agenda Based on Bibliometric Reflection, Marketing Intelligence & Planning, 41, 4, pp. 505-524, (2023); Zhong H., Huo H., Zhang X., Zheng S., Sustainable Decision-Making in a Low-Carbon Supply Chain: Fairness Preferences and Green Investment, Institute of Electrical and Electronics Engineers Access, 10, pp. 48761-48777, (2022)","A.P. Singh; Information Systems & Business Analytics, Indian Institute of Management, Ranchi, India; email: amrit.mech@gmail.com","","Routledge","","","","","","09593969","","","","English","Int. Rev. Retail Distrib. Consum. Res.","Article","Final","","Scopus","2-s2.0-85199788644" -"Tengilimoğlu D.; Orhan F.; Şenel Tekin P.; Younis M.","Tengilimoğlu, Dilaver (6507766213); Orhan, Fatih (56246387500); Şenel Tekin, Perihan (57217055970); Younis, Mustafa (8549393000)","6507766213; 56246387500; 57217055970; 8549393000","Analysis of Publications on Health Information Management Using the Science Mapping Method: A Holistic Perspective","2024","Healthcare (Switzerland)","12","3","287","","","","6","10.3390/healthcare12030287","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85184672955&doi=10.3390%2fhealthcare12030287&partnerID=40&md5=82c5644593d6e98bfa8ee4be0b9275a8","School of Business, Department of Business, Atılım University, Ankara, 06830, Turkey; Gülhane Vocational School of Health, University of Health Sciences, Ankara, 06010, Turkey; Vocational School of Health Services, Ankara University, Ankara, 06290, Turkey; School of Public Health, Jackson State University, Jackson, 39213, MS, United States","Tengilimoğlu D., School of Business, Department of Business, Atılım University, Ankara, 06830, Turkey; Orhan F., Gülhane Vocational School of Health, University of Health Sciences, Ankara, 06010, Turkey; Şenel Tekin P., Vocational School of Health Services, Ankara University, Ankara, 06290, Turkey; Younis M., School of Public Health, Jackson State University, Jackson, 39213, MS, United States","Objective: In the age of digital transformation, there is a need for a sustainable information management vision in health. Understanding the accumulation of health information management (HIM) knowledge from the past to the present and building a new vision to meet this need reveals the importance of understanding the available scientific knowledge. With this research, it is aimed to examine the scientific documents of the last 40 years of HIM literature with a holistic approach using science mapping techniques and to guide future research. Methods: This study used a bibliometric analysis method for science mapping. Co-citation and co-occurrence document analyses were performed on 630 academic publications selected from the Web of Science core collection (WoSCC) database using the keyword “Health Information Management” and inclusion criteria. The analyses were performed using the R-based software Bibliometrix (Version 4.0; K-Synth Srl), Python (Version 3.12.1; The Python Software Foundation), and Microsoft® Excel® 2016. Results: Co-occurrence analyses revealed the themes of personal health records, clinical coding and data quality, and health information management. The HIM theme consisted of five subthemes: “electronic records”, “medical informatics”, “e-health and telemedicine”, “health education and awareness”, and “health information systems (HISs)”. As a result of the co-citation analysis, the prominent themes were technology acceptance, standardized clinical coding, the success of HISs, types of electronic records, people with HIM, health informatics used by consumers, e-health, e-mobile health technologies, and countries’ frameworks and standards for HISs. Conclusions: This comprehensive bibliometric study shows that structured information can be helpful in understanding research trends in HIM. This study identified critical issues in HIM, identified meaningful themes, and explained the topic from a holistic perspective for all health system actors and stakeholders who want to work in the field of HIM. © 2024 by the authors.","bibliometric analysis; electronic records; health information management","","","","","","","","Kraus S., Schiavone F., Pluzhnikova A., Invernizzi A.C., Digital transformation in healthcare: Analyzing the current state-of-research, J. Bus. Res, 123, pp. 557-567, (2021); Stoumpos A.I., Kitsios F., Talias M.A., Digital transformation in healthcare: Technology acceptance and its applications, Int. J. Environ. Res. 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Inform, 71, pp. 70-81, (2017); Hayrinen K., Saranto K., Nykanen P., Definition, structure, content, use and impacts of electronic health records: A review of the research literature, Int. J. Med. Inform, 77, pp. 291-304, (2008)","P. Şenel Tekin; Vocational School of Health Services, Ankara University, Ankara, 06290, Turkey; email: ptekin@ankara.edu.tr","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","22279032","","","","English","Healthcare (Basel)","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85184672955" -"Maharani I.A.K.; Alfina A.; Indawati N.","Maharani, Ida Ayu Kartika (57371438900); Alfina, Alfina (59129947800); Indawati, Nurul (57202892713)","57371438900; 59129947800; 57202892713","Strategic Leadership and Organizational Innovation: Bibliometric Overview (1993-2022)","2024","Journal of Scientometric Research","13","3","","849","865","16","2","10.5530/jscires.20041230","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85211023449&doi=10.5530%2fjscires.20041230&partnerID=40&md5=31a1458976fcc285cbe2b9134f25b944","Faculty of Dharma Duta, Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar, Indonesia; Department of Management, Universitas Internasional Semen Indonesia, Indonesia; Department of Management, Universitas Negeri Surabaya, Indonesia","Maharani I.A.K., Faculty of Dharma Duta, Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar, Indonesia; Alfina A., Department of Management, Universitas Internasional Semen Indonesia, Indonesia; Indawati N., Department of Management, Universitas Negeri Surabaya, Indonesia","This study maps the development of the intersection between strategic leadership and organizational innovation through a bibliometric analysis of 111 Scopus-indexed articles published from 1993 to 2022. Addressing a gap in the literature, this research explores the patterns and trends of this intersection, which had not been holistically analyzed. The novelty of this study lies in its comprehensive identification of thematic clusters, publication trends, and key contributors to the field, providing a unique and detailed bibliometric perspective on how strategic leadership influences organizational innovation, particularly in the context of Industry 4.0 and technological advancements. Our findings reveal substantial growth in scholarly interest post-2005, peaking in 2020-2021, driven by the rise of Industry 4.0 and the increasing importance of leadership in fostering organizational innovation. The United States, China, and Australia are the leading contributors, with key institutions such as Tennessee Technological University and the University of Pretoria driving research in this field. The analysis, conducted using VOSviewer and Bibliometrix, identified five thematic clusters : strategic leadership traits, open innovation, leadership's impact on firm performance, competitive advantage, and contextual factors influencing leadership. This underscores the critical role of strategic leadership in navigating technological advancements and fostering organizational adaptability. Co-citation analysis highlighted seminal works by Bantel, Hambrick, and Howell, shaping the foundational frameworks of the field. Despite the inherent limitations of bibliometric methods, the study emphasizes the need for further exploration of emerging themes, such as CEO leadership styles, ambidexterity, and grassroots innovation. The findings suggest that adaptable leadership practices and enhanced collaboration between CEOs and Boards of Directors are vital in driving innovation and shaping governance structures. These insights should inform future policy-making and encourage cross-border research collaborations in strategic leadership and innovation. © 2024 Phcog.Net. All rights reserved.","Bibliometric; Bibliometrix; Cluster analysis; Organizational innovation; Science mapping; Scopus; Strategic leadership; VOSviewer","","","","","","","","Ambilichu CA, Omoteso K, Yekini LS., Strategic leadership and firm performance: the mediating role of ambidexterity in professional services small- and medium-sized enterprises, Eur Manag Rev, 20, 3, pp. 493-511, (2023); Sariol AM, Abebe MA., The influence of CEO power on explorative and exploitative organizational innovation, J Bus Res, 73, pp. 38-45, (2017); Cortes AF, Herrmann P., Strategic leadership of innovation: A framework for future research, Int J Manag Rev, 23, 2, pp. 224-243, (2021); Xia C, Bing Y., Strategic leadership, environmental optimisation, and regional innovation performance with the regional innovation system coupling synergy degree: evidence from China, Technol Anal Strateg Manag, pp. 1-14, (2022); Wang Q, Zhang W., Research on the evolution path of business ecosystem of platform enterprises, 517, pp. 476-484, (2021); Singh A, Lim WM, Jha S, Kumar S, Ciasullo MV., The state of the art of strategic leadership, J Bus Res, 158, (2023); Talmar M, Walrave B, Podoynitsyna KS, Holmstrom J, Romme AG., Mapping, analyzing and designing innovation ecosystems: the Ecosystem Pie Model, Long Range Plann, 53, 4, (2020); Avelino F., Theories of power and social change. 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Meyer E, Scheepers C., Contextual leadership of a multi-partner approach to health care innovation, Emerald Emerg Mark Case Stud, 7, 1, pp. 1-29, (2017); Phalswal S., Mapping the grassroots innovation research: A bibliometric analysis and future agenda, Journal of Scientometric Research, 12, 3, pp. 727-738, (2023); Uludag K., Rethinking the publish or do not graduate paradigm: balancing graduation requirements and scientific integrity, Engaging higher education teachers and students with transnational leadership, pp. 165-177, (2024)","I.A.K. Maharani; Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar, Indonesia; email: kartikamaharani@uhnsugriwa.ac.id","","Phcog.Net","","","","","","23216654","","","","English","J. Scientometr. Res.","Article","Final","","Scopus","2-s2.0-85211023449" -"Utegenova A.B.; Yermagambetova A.P.; Kabdrakhmanova G.B.; Khamidulla A.A.; Urasheva Z.U.; Kenzhinа N.K.; Zhussupova Z.; Nurlanova G.N.","Utegenova, Aigerim B. (57562735700); Yermagambetova, Aigul P. (57221325675); Kabdrakhmanova, Gulnar B. (56298142600); Khamidulla, Alima A. (56297934500); Urasheva, Zhanylsyn U. (59702057300); Kenzhinа, Nazym K. (59701773000); Zhussupova, Zhanna (57189324290); Nurlanova, Gulzhanat N. (58741830200)","57562735700; 57221325675; 56298142600; 56297934500; 59702057300; 59701773000; 57189324290; 58741830200","Bibliometric Analysis of Alpha-Synuclein Determination by Biopsy in Peripheral Tissues of Patients With Parkinson’s Disease","2025","International Journal of Telemedicine and Applications","2025","1","6469893","","","","0","10.1155/ijta/6469893","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105000465677&doi=10.1155%2fijta%2f6469893&partnerID=40&md5=22f047118ee7aff5862664a3e6fb6344","Department of Neurology, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; The Course of Therapy, West Kazakhstan High Medicine College, Uralsk, Kazakhstan; Department of Neurology and Psychiatry, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; Department of Infectious Diseases, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan","Utegenova A.B., Department of Neurology, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; Yermagambetova A.P., Department of Neurology, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; Kabdrakhmanova G.B., Department of Neurology, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; Khamidulla A.A., Department of Neurology, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; Urasheva Z.U., Department of Neurology, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; Kenzhinа N.K., The Course of Therapy, West Kazakhstan High Medicine College, Uralsk, Kazakhstan; Zhussupova Z., Department of Neurology and Psychiatry, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; Nurlanova G.N., Department of Infectious Diseases, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan","Study Evaluation: The bibliometric analysis of the published results of the alpha-synuclein (α-syn) detection study in the peripheral tissues of patients with Parkinson’s disease was carried out by us to study scientific activity and scientific productivity, to measure the quantitative and qualitative characteristics of scientific publications, author productivity, and citation of works, as well as the degree of interrelation between authors, journals, institutes, and countries. Purpose: This study is aimed at bibliometrically analyzing the results of studies on the detection of α-syn in peripheral tissue biopsy of patients with Parkinson’s disease from 2013 to 2023. Methods: The data was extracted from the Scopus database collection using an inclusive search strategy. Performance analysis and science mapping were conducted using RStudio v.4.3.1 with the bibliometrix R-package. The analyzed data encompassed trends in publication and citation and the identification of leading institutions, primary sources, authors, and collaborative countries. Results: A total of 124 relevant studies from 53 different sources were thoroughly analyzed. The analysis included the materials of 843 authors, which together gave an impressive average of 37.67 citations per document over the past decade. The annual growth rate in this area of research, according to calculations, was 10.84%, indicating a steady increase in the number of publications over the study period. The huge volume of research results is highlighted by the inclusion of 231 unique keywords of authors. Conclusion: Studies on the detection of pathological α-syn in peripheral tissues for early morphological verification of the diagnosis of Parkinson’s disease are relevant in clinical neurology. α-syn detected in the skin biopsy of patients on the basis of this study and data from the world literature meets the requirements for biomarkers. Copyright © 2025 Aigerim B. Utegenova et al. International Journal of Telemedicine and Applications published by John Wiley & Sons Ltd.","alpha-synuclein; bibliometric analysis; biopsy; Parkinson’s disease","Bibliographies; Neurodegenerative diseases; alpha synuclein; biological marker; Alpha-synuclein; Bibliometrics analysis; Parkinson’s disease; Peripheral tissue; Qualitative characteristics; Quantitative characteristics; Scientific activity; Scientific publications; Synuclein; Tissue biopsies; bibliometrics; controlled study; diagnosis; growth rate; human; human tissue; Parkinson disease; review; skin biopsy; telemedicine; Biopsy","","alpha synuclein, 154040-18-3","","","Michael J. Fox Foundation for Parkinson's Research, MJFF","However, bibliometric analysis is not without limitations. Relying solely on a single database might overlook pertinent publications. Additionally, publication quantity does not necessarily equate to research quality, and prevailing trends might occasionally reflect transient scientific fashions rather than substantive scientific progress. Globally, researchers are investigating for analyzing biopsies from various sites, such as the sigmoid colon, skin, and submandibular salivary glands, to detect \u2010syn for PD diagnosis. Histological differentiation between pathological and normal peripheral \u2010syn in biopsies presents challenges. These may stem from diverse research methodologies, biopsy site and depth variations, storage media, the use of nonspecific antibodies, and a lack of blind replication in independent studies [ 13 \u2013 15 ]. Supported by the Michael J. Fox Foundation, the Fox Foundation for Parkinson\u2019s Research has conducted a large multicenter study since 2013, focusing on standardized detection methods for \u2010syn in peripheral tissues [ 16 , 17 ]. \u03B1 \u03B1 \u03B1 ","Carling P.J., Mortiboys H., Green C., Mihaylov S., Sandor C., Schwartzentruber A., Taylor R., Wei W., Hastings C., Wong S., Lo C., Evetts S., Clemmens H., Wyles M., Willcox S., Payne T., Hughes R., Ferraiuolo L., Webber C., Hide W., Wade-Martins R., Talbot K., Hu M.T., Bandmann O., Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson’s disease, Progress in Neurobiology, 187, (2020); Giuliano C., Cerri S., Cesaroni V., Blandini F., Relevance of biochemical deep phenotyping for a personalised approach to Parkinson’s disease, Neuroscience, 511, pp. 100-109, (2023); Kim J.Y., Nam Y., Rim Y.A., Ju J.H., Review of the current trends in clinical trials involving induced pluripotent stem cells, Stem Cell Reviews and Reports, 18, pp. 142-154, (2022); Cao Y., Tian W., Wu J., Song X., Cao L., Luan X., DNA hypermethylation of NOTCH2NLC in neuronal intranuclear inclusion disease: a case-control study, Journal of Neurology, 269, pp. 6049-6057, (2022); Lempriere S., Skin α-synuclein differentiates synucleinopathies, Nature Reviews Neurology, 19, (2023); Mazzetti S., Calogero A.M., Pezzoli G., Cappelletti G., Cross-talk between α-synuclein and the microtubule cytoskeleton in neurodegeneration, Experimental Neurology, 359, (2023); Andreasson M., Svenningsson P., Update on alpha-synuclein-based biomarker approaches in the skin, submandibular gland, gastrointestinal tract, and biofluids, Current Opinion in Neurology, 34, pp. 572-577, (2021); Bellomo G., De Luca C.M.G., Paoletti F.P., Gaetani L., Moda F., Parnetti L., α-Synuclein seed amplification assays for diagnosing synucleinopathies, Neurology, 99, pp. 195-205, (2022); Heinzel S., Berg D., Gasser T., Chen H., Yao C., Postuma R.B., And the MDS Task Force on the Definition of Parkinson’s Disease, Update of the MDS Research Criteria for Prodromal Parkinson’s Disease, Movement Disorders, 34, pp. 101464-101470, (2019); Aria M., Cuccurullo C., bibliometrix : an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, pp. 959-975, (2017); Alves F.I.A.B., Exemplifying the Bradford’s Law: an analysis of recent research (2014-2019) on capital structure, Revista Ciências Sociais em Perspectiva, 18, pp. 92-101, (2019); Ablakimova N., Smagulova G.A., Rachina S., Mussina A.Z., Zare A., Mussin N.M., Kaliyev A.A., Shirazi R., Tanideh N., Tamadon A., Bibliometric analysis of global research output on antimicrobial resistance among pneumonia pathogens (2013–2023), Antibiotics, 12, (2023); Donadio V., Incensi A., Rizzo G., Westermark G.T., Devigili G., de Micco R., Tessitore A., Nyholm D., Parisini S., Nyman D., Tedeschi G., Eleopra R., Ingelsson M., Liguori R., Phosphorylated α-synuclein in skin Schwann cells: a new biomarker for multiple system atrophy, Brain, 146, pp. 1065-1074, (2023); Gibbons C., Wang N., Rajan S., Kern D., Palma J.A., Kaufmann H., Freeman R., Cutaneous α-synuclein signatures in patients with multiple system atrophy and Parkinson disease, Neurology, 100, pp. e1529-e1539, (2023); Gibbons C.H., Chapter 75 - Cutaneous autonomic innervation: assessment by skin biopsy, Primer on the Autonomic Nervous System (Fourth Edition), pp. 433-438, (2023); Beach T.G., Serrano G.E., Kremer T., Canamero M., Dziadek S., Sade H., Derkinderen P., Corbille A.G., Letournel F., Munoz D.G., White C.L., Schneider J., Crary J.F., Sue L.I., Adler C.H., Glass M.J., Intorcia A.J., Walker J.E., Foroud T., Coffey C.S., Ecklund D., Riss H., Gossmann J., Konig F., Kopil C.M., Arnedo V., Riley L., Linder C., Dave K.D., Jennings D., Seibyl J., Mollenhauer B., Chahine L., Guilmette L., Russell D., Noyes-Lloyd C., Mitchell C., Smith D., Potter M., Case R., Lott D., Duffy A., Hogarth P., Cresswell M., Akhtar R., Purri R., Amara A., Blair C., Keshavarzian A., Marras C., Visanji N., Rothberg B., Oza V., Immunohistochemical method and histopathology judging for the systemic synuclein sampling study (S4), The Systemic Synuclein Sampling Study (S4), 77, pp. 793-802, (2018); Visanji N.P., Mollenhauer B., Beach T.G., Adler C.H., Coffey C.S., Kopil C.M., Dave K.D., Foroud T., Chahine L., Jennings D., And the Systemic Synuclein Sampling Study (S4), The systemic synuclein sampling study: Toward a biomarker for Parkinson’s disease, Biomarkers in Medicine, 11, no. 4, pp. 359-368, (2017); Donadio V., Incensi A., Rizzo G., Fileccia E., Ventruto F., Riva A., Tiso D., Recchia M., Vacchiano V., Infante R., Petrangolini G., Allegrini P., Avino S., Pantieri R., Mostacci B., Avoni P., Liguori R., The effect of curcumin on idiopathic Parkinson disease: a clinical and skin biopsy study, Journal of Neuropathology and Experimental Neurology, 81, pp. 545-552, (2022); Kuzkina A., Bargar C., Schmitt D., Rossle J., Wang W., Schubert A.L., Tatsuoka C., Gunzler S.A., Zou W.Q., Volkmann J., Sommer C., Doppler K., Chen S.G., Diagnostic value of skin RT-QuIC in Parkinson’s disease: a two-laboratory study, npj Parkinson′s Disease, 7, (2021); Antelmi E., Donadio V., Incensi A., Plazzi G., Liguori R., Skin nerve phosphorylated α-synuclein deposits in idiopathic REM sleep behavior disorder, Neurology, 88, pp. 2128-2131, (2017); Liguori R., Donadio V., Wang Z., Incensi A., Rizzo G., Antelmi E., Biscarini F., Pizza F., Zou W., Plazzi G., A comparative blind study between skin biopsy and seed amplification assay to disclose pathological α-synuclein in RBD, npj Parkinson′s Disease, 9, (2023); Beach T.G., White C.L., Sabbagh M.N., Shill H.A., Adler C.H., Response to Parkinnen et al. and Jellinger, Acta Neuropathologica, 117, pp. 217-218, (2009)","A.B. Utegenova; Department of Neurology, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; email: 87012226598@mail.ru","","John Wiley and Sons Ltd","","","","","","16876415","","","","English","Int. J. Telemed. Appl.","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-105000465677" -"Ghorbani B.D.","Ghorbani, Babak Daneshvar (57225095878)","57225095878","Bibliometrix: Science Mapping Analysis with R Biblioshiny Based on Web of Science in Applied Linguistics","2024","A Scientometrics Research Perspective in Applied Linguistics","","","","197","234","37","17","10.1007/978-3-031-51726-6_8","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207205777&doi=10.1007%2f978-3-031-51726-6_8&partnerID=40&md5=bc0401d22adf040cefb4b9adba80af62","Iran University of Science and Technology, Tehran, Iran","Ghorbani B.D., Iran University of Science and Technology, Tehran, Iran","Bibliometric analysis has established itself as one of the leading approaches to visualizing a comprehensive picture of literature review across different disciplines over the past decade. As detailed in the paper, the researcher aimed to describe an open-source application that uses the R programming language to integrate a web-based interface into Biblioshiny, which performs a comprehensive analysis of the science mapping data. Bibliometrix supports a suggested methodology for conducting bibliometric analyses that can be used to conduct the analyses. This paper uses bibliometric analysis tools to visualize the relationship between published articles in the English language and technology-related publications (CALL, MALL, RALL) from 2013 to 2022. Additionally, the study followed the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. In accordance with PRISMA, 881 documents were analyzed using Bibliometrix from the WoS database. Ideally, to provide a comprehensive and systematic overview of research, two major levels of bibliometric analysis were selected, the intellectual structure and the conceptual structure, to illustrate a general and systematic overview. As a consequence, there is the possibility of gaining insight into the progress of research on specific topics, such as the most influential sources, authors, affiliations, countries, documents, and the scientific network among different constituencies as well as the evolution of research trends in the field. Hopefully, the insights provided in this paper will be useful to researchers from different disciplines who are interested in publishing authentic bibliometric studies. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.","","","","","","","","","Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aria M., Misuraca M., Spano M.S., Mapping the evolution of social research and data science on 30 years of social indicators research, Social Indicators Research, 149, 3, pp. 803-831, (2020); Briner R.B., Denyer D., Systematic Review and Evidence Synthesis as a Practice and Scholarship Tool, (2012); Broadus R.N., Toward a definition of ‘bibliometrics’, Scientometrics, 12, 5-6, pp. 373-379, (1987); Chen C., CiteSpace II: Detecting and visualizing emerging trends and transient patterns in scientific literature, Journal of the American Society for Information Science and Technology, 57, 3, pp. 359-377, (2006); Cobo M., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., SciMAT: A new science mapping analysis software tool, Journal of the Association for Information Science and Technology, 63, 8, pp. 1609-1630, (2012); Diodato V., Gellatly P., Dictionary of Bibliometrics, (2013); Eck V., Jan N., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Glanzel W., Coauthorship patterns and trends in the sciences (1980–1998): A bibliometric study with implications for database indexing and search strategies, Library Trends, 50, 3, pp. 461-473, (2002); Guler A.T., Waaijer C.J.F., Palmblad M., Scientific workflows for bibliometrics, Scientometrics, 107, 2, pp. 385-398, (2016); Harzing A.-W., Alakangas S., Google scholar, scopus and the web of science: A longitudinal and cross-disciplinary comparison, Scientometrics, 106, 2, pp. 787-804, (2016); Hubert J.J., Linguistic indicators, Social Indicators Research, 8, 2, pp. 223-255, (1980); Kessler M.M., Bibliographic coupling between scientific papers, American Documentation, 14, 1, pp. 10-25, (1963); Lei L., Dilin L., Research trends in applied linguistics from 2005 to 2016: A bibliometric analysis and its implications, Applied Linguistics, 40, 3, pp. 540-561, (2019); Linnenluecke M.K., Marrone M., Singh A.K., Conducting systematic literature reviews and bibliometric analyses, Australian Journal of Management, 45, 2, pp. 175-194, (2020); Marx W., Bornmann L., Barth A., Leydesdorff L., Detecting the historical roots of research fields by reference publication year spectroscopy (RPYS), Journal of the Association for Information Science and Technology, 65, 4, pp. 751-764, (2014); Moher D., Liberati A., Tetzlaff J., Altman D.G., Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement, Plos Medicine 6 (7), (2009); R: A language and environment for statistical computing, MSOR Connections, 1, 1, (2014); Senel E., Demir E., Bibliometric and scientometric analysis of the articles published in the journal of religion and health between 1975 and 2016, Journal of Religion & Health, 57, 4, pp. 1473-1482, (2018); Shi J., Duan K., Guangdong W., Zhang R., Feng X., Comprehensive metrological and content analysis of the public–private partnerships (PPPs) research field: A new bibliometric journey, Scientometrics, 124, 3, pp. 2145-2184, (2020); Small H., Co-citation in the scientific literature: A new measure of the relationship between two documents, Journal of the American Society for Information Science, 24, 4, pp. 265-269, (1973); Visser M.S., Van Eck N.J.V., Waltman L., Large-scale comparison of bibliographic data sources: Scopus, Web of Science, Dimensions, Crossref, and Microsoft academic, Quantitative Science Studies, 2, 1, pp. 20-41, (2021); Ware M., Mabe M., The STM Report: An Overview of Scientific and Scholarly Journal Publishing, (2015); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","B.D. Ghorbani; Iran University of Science and Technology, Tehran, Iran; email: babak_daneshvar@alumni.iust.ac.ir","","Springer Nature","","","","","","","978-303151726-6; 978-303151725-9","","","English","A Scientometrics Research Perspective in Appl. Linguistics","Book chapter","Final","","Scopus","2-s2.0-85207205777" -"Farooq R.; Durst S.","Farooq, Rayees (56536529900); Durst, Susanne (24733917600)","56536529900; 24733917600","Understanding knowledge hiding in organizations: a bibliometric analysis of research trends between 2005 and 2022","2025","Global Knowledge, Memory and Communication","74","5-6","","1677","1723","46","3","10.1108/GKMC-04-2023-0133","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85164959201&doi=10.1108%2fGKMC-04-2023-0133&partnerID=40&md5=02e3b3ffdcb7fe0b6f7f9b5bc4c6411f","Faculty of Business, Sohar University, Sohar, Oman; Department of Business Administration, Reykjavik University, Reykjavik, Iceland and Department of Business Administration, Tallinn University of Technology, Tallinn, Estonia","Farooq R., Faculty of Business, Sohar University, Sohar, Oman; Durst S., Department of Business Administration, Reykjavik University, Reykjavik, Iceland and Department of Business Administration, Tallinn University of Technology, Tallinn, Estonia","Purpose: Considering the increasing interest devoted to knowledge hiding in the workplace and academic research, the aim of this study is to analyze the existing literature on knowledge hiding to understand and trace how it has evolved over time and to uncover emerging areas for future research. Design/methodology/approach: The study used performance analysis and science mapping to analyze a sample of 243 studies published between 2005 and 2022. The study focused on analyzing the scientific productivity of articles, themes and authors. Findings: The results of performance and science mapping analysis indicate that the concept of knowledge hiding behavior evolved recently and a majority of the studies have been conducted in the past decade. The study found that knowledge hiding is still in its infancy and has been studied in relation to other themes such as knowledge sharing, knowledge management, knowledge withholding and knowledge transfer. The study identified emerging themes, productive authors and countries, affiliations, collaboration network of authors, countries and institutions and co-occurrence of keywords. Originality/value: Compared to the recent developments in the knowledge hiding behavior, the present study is more comprehensive in terms of the methods and databases used. The results of the study contribute to the existing literature on knowledge hiding and knowledge withholding. © 2023, Emerald Publishing Limited.","Bibliometrix; Biblioshiny; Hiding knowledge; Knowledge hiding; Knowledge withholding; Performance analysis; Science mapping; Scopus; Web of Science; Withholding knowledge","","","","","","","","Akter S., Uddin M.H., Tajuddin A.H., Knowledge mapping of microfinance performance research: a bibliometric analysis, International Journal of Social Economics, 48, 3, pp. 399-418, (2021); Alonso S., Cabrerizo F.J., Herrera-Viedma E., Herrera F., h‐index: a review focused in its variants, computation and standardization for different scientific fields, Journal of Informetrics, 3, 4, pp. 273-289, (2009); Anand P., Hassan Y., Knowledge hiding in organizations: everything that managers need to know, Development and Learning in Organizations: An International Journal, 33, 6, pp. 12-15, (2019); Anand A., Offergelt F., Anand P., Knowledge hiding – a systematic review and research agenda, Journal of Knowledge Management, 26, 6, pp. 1438-1457, (2022); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bari M.W., Abrar M., Shaheen S., Bashir M., Fanchen M., Knowledge hiding behaviors and team creativity: the contingent role of perceived mastery motivational climate, SAGE Open, 9, 3, (2019); Bar-Ilan J., Which h-index?—a comparison of WoS, scopus and google scholar, Scientometrics, 74, 2, pp. 257-271, (2008); Bernatovic I., Slavec Gomezel A., Cerne M., Mapping the knowledge-hiding field and its future prospects: a bibliometric co-citation, co-word, and coupling analysis, Knowledge Management Research and Practice, 20, 3, pp. 1-16, (2021); Borgatti S.P., Centrality and network flow, Social Networks, 27, 1, pp. 55-71, (2005); Bornmann L., What is societal impact of research and how can it be assessed? 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Farooq; Faculty of Business, Sohar University, Sohar, Oman; email: rayeesfarooq@rediffmail.com","","Emerald Publishing","","","","","","25149342","","","","English","Glob. Knowl., Mem. Commun.","Article","Final","","Scopus","2-s2.0-85164959201" -"Kaya A.","Kaya, Ayla (57195068978)","57195068978","Bibliometric Analysis of the 40-Year History of Public Health Nursing (1984–2024)","2025","Public Health Nursing","","","","","","","0","10.1111/phn.13574","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105005555904&doi=10.1111%2fphn.13574&partnerID=40&md5=78f4491d20ef12a6a73f643122f1a5f9","Faculty of Nursing, Pediatric Nursing Department, Akdeniz University, Antalya, Turkey","Kaya A., Faculty of Nursing, Pediatric Nursing Department, Akdeniz University, Antalya, Turkey","Objective: This study was conducted in honor of Public Health Nursing’s 40th anniversary. The study was unique as it provided the first bibliometric analysis revealing the evolution of Public Health Nursing's publications. Design and Methods: This study was a bibliometric analysis. The study was carried out by analyzing 2985 publications. Data were collected from the Web of Science Core Collection (WoSCC) database on December 31, 2024. The data analysis and graphical presentation were conducted using the Bibliometrix Package in R software and WoSCC. Results: Public Health Nursing has had a rapidly growing impact on the field of public health nursing in terms of publications and citations. The most productive and collaborative country was the United States. “COVID-19,” “vaccination,” “older adults,” “knowledge,” “climate change,” and “attitude” were the trending topics in recent years. According to the thematic map, more studies addressing the topics of “physical activity, obesity, adolescents” were required. Conclusion: The journal has an increasing contribution and impact on public health nursing studies. It was determined that the journal's publishing network was in good condition worldwide, and the thematic diversity was high. In addition, focusing on the topics that need further study can contribute to the field of public health nursing. © 2025 Wiley Periodicals LLC.","bibliometrics; Public Health Nursing; science mapping; Web of Science Core Collection","","","","","","","","Alasagheirin M., Canales M.K., Decker E., Attitudes and Perceptions Toward COVID-19 Virus and Vaccines Among a Somali Population in Northern Wisconsin, Public Health Nursing, 41, pp. 151-163, (2024); Aria M., Cuccurullo C., bibliometrix: An R-Tool for Comprehensive Science Mapping Analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Azizoglu F., Terzi B., Sonmez Duzkaya D., Global Trends in Technology-Dependent Children, Home Care, and Parental Discharge Education: A Bibliometric Analysis Using Biblioshiny, Journal of Pediatric Nursing, 79, pp. e213-e222, (2024); Cava M.A., Fay K.E., Beanlands H.J., McCay E.A., Wignall R., The Experience of Quarantine for Individuals Affected by SARS in Toronto, Public Health Nursing, 22, 5, pp. 398-406, (2005); Web of Science, (2024); Web of Science, (2024); Dagistan Akgoz A., Kaya A., Research Trends and Hot Topics of Nursing Studies on Hypertension: A Retrospective Bibliometric Analysis From 1979 to 2024, Public Health Nursing, 42, pp. 494-503, (2025); DiCasmirro J., Tranmer J., Davison C., Et al., Public Health Interventions Targeting the Prevention of Adolescent Vaping: A Scoping Review, Public Health Nursing, 42, pp. 604-614, (2025); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to Conduct a Bibliometric Analysis: An Overview and Guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Ern J., Chaidez V., Trout K.E., Karsting K., Su D., Perspectives on Certification of Community Health Workers: A Statewide Mixed-Methods Assessment in Nebraska, Public Health Nursing, 40, 4, pp. 535-542, (2023); Ho M.T.H., Chan J.K.N., Lo H.K.Y., Et al., Risk of Mortality and Complications in People With Depressive Disorder and Diabetes Mellitus: A 20-Year Population-Based Propensity Score-Matched Cohort Study, European Neuropsychopharmacology, 92, pp. 10-18, (2025); Kaya A., Isler Dalgic A., Evaluating Workload and Manpower Planning Among Pediatric Emergency Department Nurses in Turkey During COVID-19: A Cross-Sectional, Multicenter Study, Journal of Pediatric Nursing, 65, pp. 69-74, (2022); Kaya A., Tuzcu A., A Bibliometric Analysis of the 36 Year History of Cancer Nursing (1987-2023), Cancer Nursing, 47, 4, pp. 252-260, (2024); Kose S.K., Aydogdu G., Demir E., Kiraz M., Looking Backward Toward the Future: A Bibliometric Analysis of the Last 40 Years of Meningioma Global Outcomes, Medicine, 103, 32, (2024); Li N., Yu X., Characteristic Analysis of China's Actions Against the COVID-19 in Schools and Comparison With Other Countries, Public Health Nursing, 41, 2, pp. 255-263, (2024); Lopez-Robles J.R., Cobo M.J., Gutierrez-Salcedo M., Martinez-Sanchez M.A., Gamboa-Rosales N.K., Herrera-Viedma E., 30th Anniversary of Applied Intelligence: A Combination of Bibliometrics and Thematic Analysis Using SciMAT, Applied Intelligence, 51, 9, pp. 6547-6568, (2021); Merigo J.M., Mas-Tur A., Roig-Tierno N., Ribeiro-Soriano D., A Bibliometric Overview of the Journal of Business Research Between 1973 and 2014, Journal of Business Research, 68, 12, pp. 2645-2653, (2015); Montazeri A., Mohammadi S., Hesari P.M., Et al., Preliminary guideline for reporting bibliometric reviews of the biomedical literature (BIBLIO): a minimum requirements, (2023); Musio M.E., Russo M., Barbieri M., Et al., Influencing Factors of Nurses' Well-Being in Critical Care During Pandemic Era: A Systematic Review, Public Health Nursing, 65, pp. 1-21, (2025); Ozen Cinar I., General, Social, and Intellectual Structure of Breastfeeding Studies in the Field of Nursing: A Bibliometric Analysis on R Software, Journal of Pediatric Nursing, 80, pp. e24-e33, (2025); Recto P., Lesser J., Zapata J., Gandara E., Idar A.Z., Castilla M., Supporting Community Health Workers During the COVID-19 Pandemic: A Mixed Methods Pilot Study, Public Health Nursing, 40, pp. 63-72, (2023); SCImago, (2024); Scott S., Clancy T.L., Ferreira C., Journey to Authentic Learning—Enacting Reciprocity in Nursing Graduate Education, Witness: The Canadian Journal of Critical Nursing Discourse, 2, 1, pp. 111-121, (2020); Shamansky S.L., Young K.J., The Community is a Cauldro, Public Health Nursing, 1, 1, pp. 1-2, (1984); Swider S.M., Outcome Effectiveness of Community Health Workers: An Integrative Literature Review, Public Health Nursing, 19, 1, pp. 11-20, (2002); Tayhan A., Isik K., Relationship Between Primary School Teachers' COVID-19 Fear Levels and COVID-19 Vaccine Attitudes After the Start of Face-to-Face Education During the Pandemic Period: A School Health Study, Public Health Nursing, 42, pp. 113-122, (2025); Tripathi M., Kumar S., Sonker S.K., Babbar P., Occurrence of Author Keywords and Keywords Plus in Social Sciences and Humanities Research : A Preliminary Study, COLLNET Journal of Scientometrics and Information Management, 12, 2, pp. 215-232, (2018); Warnes G., Bolker B., Bonebakker L., Et al., Gplots: Various R Programming Tools for Plotting Data, (2024); White B., Hetzel A., Willgerodt M., Durkee-Neuman E., Nguyen L., The Impact of COVID-19 on School Nursing: A Qualitative Survey of Stressors Faced by School Nurses, Public Health Nursing, 41, 3, pp. 543-554, (2024); Yalcinkaya T., Unsal E., Thirty-Five Years of Knowledge in Transcultural Nursing: A Bibliometric Analysis of Journal of Transcultural Nursing, (2025); Yanbing S., Ruifang Z., Chen W., Shifan H., Hua L., Zhiguang D., Bibliometric Analysis of Journal of Nursing Management From 1993 to 2018, Journal of Nursing Management, 28, 2, pp. 317-331, (2020); Yu J., Chen S., Yang J., Et al., Childhood and Adolescent Overweight/Obesity Prevalence Trends in Jiangsu, China, 2017–2021: An Age-Period-Cohort Analysis, Public Health Nursing, 42, pp. 754-761, (2024); Zeleznik D., Blazun Vosner H., Kokol P., A Bibliometric Analysis of the Journal of Advanced Nursing, 1976–2015, Journal of Advanced Nursing, 73, 10, pp. 2407-2419, (2017); Zhu J., Liu W., A Tale of Two Databases: The Use of Web of Science and Scopus in Academic Papers, Scientometrics, 123, 1, pp. 321-335, (2020)","A. Kaya; Faculty of Nursing, Pediatric Nursing Department, Akdeniz University, Antalya, Turkey; email: aylakaya@akdeniz.edu.tr","","John Wiley and Sons Inc","","","","","","07371209","","PHNUE","","English","Public Health Nurs.","Article","Article in press","","Scopus","2-s2.0-105005555904" -"Ventaja-Cruz J.; Cuevas Rincón J.M.; Tejada-Medina V.; Martín-Moya R.","Ventaja-Cruz, Javier (57219127260); Cuevas Rincón, Jesús M. (57212108419); Tejada-Medina, Virginia (57219123496); Martín-Moya, Ricardo (57193726043)","57219127260; 57212108419; 57219123496; 57193726043","A Bibliometric Study on the Evolution of Women’s Football and Determinants Behind Its Growth over the Last 30 Years","2024","Sports","12","12","333","","","","1","10.3390/sports12120333","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85213463185&doi=10.3390%2fsports12120333&partnerID=40&md5=23bad801fab5087a7b099d8f2089bff7","Department of Physical Education and Sports, Faculty of Education and Sport Sciences, University of Granada, Melilla Campus, ES, Melilla, 52071, Spain; Melilla Football Federation, ES, Melilla, 52001, Spain; Department of Research and Diagnostic Methods in Education, Faculty of Education and Sport Sciences, University of Granada, Melilla Campus, Melilla, ES-52071, Spain","Ventaja-Cruz J., Department of Physical Education and Sports, Faculty of Education and Sport Sciences, University of Granada, Melilla Campus, ES, Melilla, 52071, Spain, Melilla Football Federation, ES, Melilla, 52001, Spain; Cuevas Rincón J.M., Department of Research and Diagnostic Methods in Education, Faculty of Education and Sport Sciences, University of Granada, Melilla Campus, Melilla, ES-52071, Spain; Tejada-Medina V., Department of Physical Education and Sports, Faculty of Education and Sport Sciences, University of Granada, Melilla Campus, ES, Melilla, 52071, Spain; Martín-Moya R., Department of Physical Education and Sports, Faculty of Education and Sport Sciences, University of Granada, Melilla Campus, ES, Melilla, 52071, Spain","Background: The evolution of women’s football over the past three decades has been remarkable in terms of development, visibility, and acceptance, transforming into a discipline with growing popularity and professionalization. Significant advancements in gender equality and global visibility have occurred, and the combination of emerging talent, increasing commercial interest, and institutional support will continue to drive the growth and consolidation of women’s football worldwide. Methods: The purpose of this study was to present a bibliometric analysis of articles on the evolution of women’s football in terms of scientific production as well as its causes and motivations over the past 30 years (1992–2024). A total of 128 documents indexed in the Web of Science database were reviewed. Outcome measures were analyzed using RStudio version 4.3.1 (Viena, Austria) software and the Bibliometrix data package to evaluate productivity indicators including the number of articles published per year, most productive authors, institutions, countries, and journals as well as identify the most cited articles and common topics. Results: Scientific production on women’s football has shown sustained growth, particularly since 2010. Key research areas have focused on injury prevention, physical performance, psychosocial factors, motivation, and leadership. The United States, the United Kingdom, and Spain have emerged as the most productive countries in this field, with strong international collaboration reflected in co-authorship networks. Conclusions: The study revealed a clear correlation between the evolution of women’s football and the increase in scientific production, providing a strong foundation for future research on emerging topics such as the importance of psychological factors, sport motivation and emotional well-being on performance, gender differences at the physiological and biomechanical levels, or misogyny in social networks, thus promoting comprehensive development in this sport modality. © 2024 by the authors.","Biblioshiny; female soccer; motivation; science mapping; scientific production; women’s sports","","","","","","","","Griffin J., Horan S., Keogh J., Dodd K., Andreatta M., Minahan C., Contextual Factors Influencing the Characteristics of Female Football Players, J. Sports Med. Phys. Fit, 61, pp. 218-232, (2021); Hardy W., Balliauw M., Vandenbruaene J., To Play or Not to Play? What Drives Girls’ and Women’s Participation in Football?, J. Glob. Sport Manag, pp. 1-24, (2024); Williams J., Pope S., Cleland J., ‘Genuinely in Love with the Game’ Football Fan Experiences and Perceptions of Women’s Football in England, Sport Soc, 26, pp. 285-301, (2023); Tjonndal A., Skirbekk S.B., Rosten S., Rogstad E.T., ‘Women Play Football, Not Women’s Football’: The Potentials and Paradoxes of Professionalisation Expressed at the UEFA Women’s EURO 2022 Championship, Eur. J. Sport Soc, 21, pp. 276-294, (2024); Valenti M., Scelles N., Morrow S., The Determinants of Stadium Attendance in Elite Women’s Football: Evidence from the FA Women’s Super League, Eur. Sport Manag. Q, pp. 1-17, (2024); Ford P.R., Hodges N.J., Broadbent D., O'Connor D., Scott D., Datson N., Andersson H.A., Williams A.M., The Developmental and Professional Activities of Female International Soccer Players from Five High-Performing Nations, J. Sports Sci, 38, pp. 1432-1440, (2020); He Y., Su G., Wang L., Qian H., Girls Play Basketball Too? 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Tejada-Medina; Department of Physical Education and Sports, Faculty of Education and Sport Sciences, University of Granada, Melilla Campus, Melilla, ES, 52071, Spain; email: vtejada@ugr.es","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20754663","","","","English","Sports","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85213463185" -"Damayanti A.D.; Gani H.; Zhipeng F.; Gani H.; Zuhriyah S.; Nurani; Djabir S.N.; Wardani N.I.","Damayanti, Annisa Dwi (58580830800); Gani, Hamdan (57201299496); Zhipeng, Feng (57219566788); Gani, Helmy (57211438750); Zuhriyah, Sitti (59740306400); Nurani (59763172800); Djabir, St. Nurhayati (59763631200); Wardani, Nur Ilmiyanti (59763023300)","58580830800; 57201299496; 57219566788; 57211438750; 59740306400; 59763172800; 59763631200; 59763023300","Bibliometric and Content Analysis of Large Language Models Research in Software Engineering: The Potential and Limitation in Software Engineering","2025","International Journal of Advanced Computer Science and Applications","16","4","","344","356","12","0","10.14569/IJACSA.2025.0160436","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105004044722&doi=10.14569%2fIJACSA.2025.0160436&partnerID=40&md5=685df32ba53922b081793c2c60cd24af","Department of Environmental Engineering, Faculty of Engineering, Hasanuddin University, Makassar, Indonesia; Department of Machinery Automation System, ATI Makassar Polytechnic, Makassar, Indonesia; School of Culture Creativity and Media, Hangzhou Normal University, Zhejiang, Hangzhou, China; Department of Industrial Hygiene, Faculty of Public Health, Occupational Health and Safety, Makassar College of Health Sciences, Indonesia; Department of Computer System, Universitas Handayani Makassar, Makassar, Indonesia; Department of Information Systems and Technology, Institut Teknologi dan Bisnis Nobel Indonesia, Jl. Sultan Alauddin No.212, Makassar, 90221, Indonesia; Department of Informatics Engineering, Universitas Handayani Makassar, Makassar, Indonesia","Damayanti A.D., Department of Environmental Engineering, Faculty of Engineering, Hasanuddin University, Makassar, Indonesia; Gani H., Department of Machinery Automation System, ATI Makassar Polytechnic, Makassar, Indonesia; Zhipeng F., School of Culture Creativity and Media, Hangzhou Normal University, Zhejiang, Hangzhou, China; Gani H., Department of Industrial Hygiene, Faculty of Public Health, Occupational Health and Safety, Makassar College of Health Sciences, Indonesia; Zuhriyah S., Department of Computer System, Universitas Handayani Makassar, Makassar, Indonesia; Nurani, Department of Information Systems and Technology, Institut Teknologi dan Bisnis Nobel Indonesia, Jl. Sultan Alauddin No.212, Makassar, 90221, Indonesia; Djabir S.N., Department of Machinery Automation System, ATI Makassar Polytechnic, Makassar, Indonesia; Wardani N.I., Department of Informatics Engineering, Universitas Handayani Makassar, Makassar, Indonesia","Large Language Models (LLM) is a type of artificial neural network that excels at language-related tasks. The advantages and disadvantages of using LLM in software engineering are still being debated, but it is a tool that can be utilized in software engineering. This study aimed to analyze LLM studies in software engineering using bibliometric and content analysis. The study data were retrieved from Web of Science and Scopus. The data were analyzed using two popular bibliometric approaches: bibliometric and content analysis. VOS Viewer and Bibliometrix software were used to conduct the bibliometric analysis. The bibliometric analysis was performed using science mapping and performance analysis approaches. Various bibliometric data, including the most frequently referenced publications, journals, and nations, were evaluated and presented. Then, the synthetic knowledge method was utilized for content analysis. This study examined 235 papers, with 836 authors contributing. The publications were published in 123 different journals. The average number of citations per publication is 1.44. Most publications were published in Proceedings International Conference on Software Engineering and ACM International Conference Proceeding Series, with China and the United States emerging as the leading countries. It was discovered that international collaboration on the issue was inadequate. The most often used keywords in the publications were ""software design,"" ""code (symbols),"" and ""code generation."" Following the content analysis, three themes emerged: 1) Integration of LLM into software engineering education, 2) application of LLM in software engineering, and 3) potential and limitation of LLM in software engineering. The results of this study are expected to provide researchers and academics with insights into the current state of LLM in software engineering research, allowing them to develop future conclusions. © (2025), (Science and Information Organization). All Rights Reserved.","bibliometric; content analysis; Large Language Models; LLM; software engineering","Application programs; Behavioral research; Computer aided software engineering; Computer operating systems; Computer program listings; Computer software maintenance; Computer software selection and evaluation; Engineering research; Search engines; Software packages; Software prototyping; Software quality; Software testing; Utility programs; Verification; Bibliometric; Bibliometrics analysis; Content analysis; Excel; Language model; Large language model; Modelling studies; Neural-networks; Software design","","","","","","","Roumeliotis K. I., Tselikas N. D., ChatGPT and Open-AI Models: A Preliminary Review, Future Internet, 15, 6, (2023); Chang Y., Et al., A Survey on Evaluation of Large Language Models, ACM Transactions on Intelligent Systems and Technology, 15, 3, pp. 1-45, (2024); Akbar M. A., Khan A. 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V., Stefan Posedaru B., Improving Programming Activities Using ChatGPT: A Practical Approach, Smart Innovation, Systems and Technologies, 367, pp. 307-316, (2024)","","","Science and Information Organization","","","","","","2158107X","","","","English","Intl. J. Adv. Comput. Sci. Appl.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-105004044722" -"Xu F.; Kasperskaya Y.; Sagarra M.","Xu, Feng (59474955000); Kasperskaya, Yuliya (24171159100); Sagarra, Marti (56222453400)","59474955000; 24171159100; 56222453400","The impact of FinTech on bank performance: A systematic literature review","2025","Digital Business","5","2","100131","","","","0","10.1016/j.digbus.2025.100131","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105006770350&doi=10.1016%2fj.digbus.2025.100131&partnerID=40&md5=a76dec5c43e11d077f17471ad16c2538","University of Barcelona, Spain","Xu F., University of Barcelona, Spain; Kasperskaya Y., University of Barcelona, Spain; Sagarra M., University of Barcelona, Spain","This paper investigates the impact of financial technology (FinTech) on bank performance through a comprehensive bibliometric analysis of publications from the Web of Science Core Collection Database published between 2015 and July 2024. The study employs the R-package litsearchr for keyword search string development and uses VosViewer and Bibliometrix for science mapping and network analysis. The research addresses five key questions, including research trends, influential authors and sources, geographical influences, notable research clusters, and the aspects of bank performance affected by FinTech. The paper proposes four future research directions, suggesting the exploration of alternative bank performance metrics, greater regional focus, the investigation of emerging themes such as financial inclusion and the role of entrepreneurship, and advances in methodologies. This article contributes to significantly enhancing the understanding of how FinTech is reshaping the banking industry and providing a robust foundation for future research to build upon, making it a valuable resource for both academics and practitioners interested in the intersection of technology and finance. © 2025 The Authors","Bank performance; Bibliometric analysis; Blockchain; Customer experience; Digital banking; Financial inclusion; Financial stability; FinTech; Mobile payments; Peer-to-peer lending; Regulatory frameworks; Risk management","","","","","","","","Adbi A., Natarajan S., Fintech and banks as complements in microentrepreneurship, Strategic Entrepreneurship Journal, 17, 3, pp. 585-611, (2023); Allen J.S., Pay it forward (digitally): Sizing up the global impact of electronic wages on digital payment usage, Journal of Economics and Finance, 48, 1, pp. 107-128, (2024); Anagnostopoulos I., Fintech and regtech: Impact on regulators and banks, Journal of Economics and Business, 100, July, pp. 7-25, (2018); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Asif M., Lodhi R.N., Sarwar F., Ashfaq M., Dark side whitewashes the benefits of FinTech innovations: A bibliometric overview, International Journal of Bank Marketing, 42, 1, pp. 113-132, (2024); Au Y.A., Kauffman R.J., The economics of mobile payments: Understanding stakeholder issues for an emerging financial technology application, Electronic Commerce Research and Applications, 7, 2, pp. 141-164, (2008); Banna H., Alam M.R., Impact of digital financial inclusion on ASEAN banking stability: Implications for the post-Covid-19 era, Studies in Economics and Finance, 38, 2, pp. 504-523, (2021); Banna H., Hassan M.K., Ahmad R., Alam M.R., Islamic banking stability amidst the COVID-19 pandemic: The role of digital financial inclusion, International Journal of Islamic and Middle Eastern Finance and Management, 15, 2, pp. 310-330, (2022); Barua S., Golder U., Chowdhury R.S., Sharmeen K., Implications of NFT as a sustainable fintech innovation for sustainable development and entrepreneurship, Sustainable Technology and Entrepreneurship, 4, 2, (2025); Boot A., Hoffmann P., Laeven L., Ratnovski L., Fintech: What's old, what's new?, Journal of Financial Stability, 53, (2021); Bortoluzzo A.B., Minardi A., Bortoluzzo M.M., Fernandes M.M., Assessing the impact of COVID-19 on banks’ profitability: The role of size in an emerging economy, (2024); Budgen D., Brereton P., Performing systematic literature reviews in software engineering, Proceedings - International Conference on Software Engineering, 2006, pp. 1051-1052, (2006); Bunge D., In the shadow of banking: Oversight of Fintechs and their service companies, Perspectives in Law, Business and Innovation, 301-326, (2017); Campanella F., Serino L., Battisti E., Giakoumelou A., Karasamani I., FinTech in the financial system: Towards a capital-intensive and high competence human capital reality?, Journal of Business Research, 155, (2023); Chang V., Baudier P., Zhang H., Xu Q., Zhang J., Arami M., How Blockchain can impact financial services – The overview, challenges and recommendations from expert interviewees, Technological Forecasting and Social Change, 158, April, (2020); Chang Y.W., Huang M.H., Lin C.W., Evolution of research subjects in library and information science based on keyword, bibliographical coupling, and co-citation analyses, Scientometrics, 105, 3, pp. 2071-2087, (2015); Chawla D., Joshi H., Consumer attitude and intention to adopt mobile wallet in India – An empirical study, International Journal of Bank Marketing, 37, 7, pp. 1590-1618, (2019); Chebii V., Chemaket A., Waweru C., Mutua J., Mobile banking and financial performance of commercial banks in Kenya, African Journal of Emerging Issues, 6, 9, pp. 26-38, (2024); Chen T.H., Peng J.L., Statistical and bibliometric analysis of financial innovation, Library Hi Tech, 38, 2, pp. 308-319, (2020); Chen X., He G., Li Q., Can Fintech development improve the financial inclusion of village and township banks? 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Empirical evidence from listed banks in China, Economic Change and Restructuring, 56, 6, pp. 4445-4463, (2023); Zhao J., Li X., Yu C.H., Chen S., Lee C.C., Riding the FinTech innovation wave: FinTech, patents and bank performance, Journal of International Money and Finance, 122, (2022); Zhao Q., Tsai P., Improving financial service innovation strategies for enhancing China ’ s banking industry competitive advantage during the Fintech revolution : A hybrid MCDM model, pp. 1-29, (2019)","F. Xu; Universitat de Barcelona, Business Department, Barcelona, Avda. Diagonal, 690, 08034, Spain; email: fxuxuxxx29@alumnes.ub.edu","","Elsevier B.V.","","","","","","26669544","","","","English","Digit. Bus.","Article","Final","","Scopus","2-s2.0-105006770350" -"Mota B.; Rua O.L.; Neira-Gómez I.","Mota, Beatriz (58751998600); Rua, Orlando Lima (57095989600); Neira-Gómez, Isabel (57203021376)","58751998600; 57095989600; 57203021376","New advances in science mapping and performance analysis of the open innovation and tourism relationship","2024","Journal of Open Innovation: Technology, Market, and Complexity","10","1","100154","","","","8","10.1016/j.joitmc.2023.100154","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85179080980&doi=10.1016%2fj.joitmc.2023.100154&partnerID=40&md5=df5c82033568d0acee4e4618c993f2e3","University of Santiago de Compostela, Spain; Center for Organisational and Social Studies (CEOS.PP), Portugal, and Research Center of Business Sciences (NECE), University of Beira Interior (UBI), Portugal","Mota B., University of Santiago de Compostela, Spain; Rua O.L., Center for Organisational and Social Studies (CEOS.PP), Portugal, and Research Center of Business Sciences (NECE), University of Beira Interior (UBI), Portugal; Neira-Gómez I., University of Santiago de Compostela, Spain","The number of scientific publications studying open innovation (OI) and tourism has increased since the first concept appeared. Nevertheless, there is still a gap regarding the science mapping and performance analysis of these two concepts. Although there are studies that focus on open innovation and tourism, few are studying the relationship between themes. We aimed to address this gap by reviewing the literature and searching the Scopus database using R. Bibliometrix. We identified 45 published articles between 2010 and 2022, covering 23 sources and 130 authors. The results indicate a strong collaboration network among authors. Open Innovation, Tourism, and Sustainability are the trend topics, as well as the three main keywords. The emerging topics are “open innovation in tourism”, “service innovation” and “overtourism”. Keywords, trend topics, and emerging topics can be valuable guides for researchers and help them decide which path to take in their studies in this field. This paper is a starting point for carrying out further research that relates OI to other areas of tourism, such as smart tourism or smart tourism destinations, which are highlighted in some of the most recent articles that were under this study. © 2023","Bibliometric analysis; Open innovation; R. software; Tourism","","","","","","Isabel Neira Gómez University of Santiago de Compostela; Fundação para a Ciência e a Tecnologia, FCT, (UIDP/05422/2020); Fundação para a Ciência e a Tecnologia, FCT","The Research titled “New advances in science mapping and performance analysis of the open innovation and tourism relationship” by Beatriz Mota ( University of Santiago de Compostela , Spain), Orlando Lima Rua (Center for Organisational and Social Studies, CEOS.PP, Portugal) and Isabel Neira Gómez University of Santiago de Compostela, Spain) is financially supported by Portuguese national funds through FCT - Fundação para a Ciência e Tecnologia, under the project UIDP/05422/2020 . 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Rua; Center for Organisational and Social Studies (CEOS.PP), Portugal, and Research Center of Business Sciences (NECE), University of Beira Interior (UBI), Portugal; email: orua@iscap.ipp.pt","","Elsevier B.V.","","","","","","21998531","","","","English","J. Open Innov.: Technol. Mark. Complex.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85179080980" -"Crisan G.-A.; Belciu A.; Popescu M.E.","Crisan, Georgiana-Alina (58777463800); Belciu, Anda (59661146000); Popescu, Madalina Ecaterina (56299424300)","58777463800; 59661146000; 56299424300","Digital Transformation—One Step Further to a Sustainable Economy: The Bibliometric Analysis","2025","Sustainability (Switzerland)","17","4","1477","","","","1","10.3390/su17041477","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85219193480&doi=10.3390%2fsu17041477&partnerID=40&md5=3870a22b12ba6f1e8420dc74ce55c00d","The Faculty of Economic Cybernetics, Statistics and Informatics, The Bucharest University of Economic Studies, 15–17 Dorobanti St., Sector 1, Bucharest, 010552, Romania; The National Scientific Research Institute for Labour and Social Protection, 6-8 Povernei Street, Bucharest, 010643, Romania","Crisan G.-A., The Faculty of Economic Cybernetics, Statistics and Informatics, The Bucharest University of Economic Studies, 15–17 Dorobanti St., Sector 1, Bucharest, 010552, Romania; Belciu A., The Faculty of Economic Cybernetics, Statistics and Informatics, The Bucharest University of Economic Studies, 15–17 Dorobanti St., Sector 1, Bucharest, 010552, Romania; Popescu M.E., The Faculty of Economic Cybernetics, Statistics and Informatics, The Bucharest University of Economic Studies, 15–17 Dorobanti St., Sector 1, Bucharest, 010552, Romania, The National Scientific Research Institute for Labour and Social Protection, 6-8 Povernei Street, Bucharest, 010643, Romania","Digitalization has significantly reshaped human and social life worldwide, serving as a powerful enabler of a sustainable economy, while being directly aligned with Sustainable Development Goal 9, among others. The literature on digitalization and sustainability boosted since 2017, confirming its importance. Unlike most previous studies, this paper extracted articles from both the Scopus and Web of Science platforms, and the bibliometric analysis was conducted using the new Python library, pyBibX, for the cleaned concatenated dataset, as well as Bibliometrix in R for the parallel analysis on the two platforms. We conducted both a performance analysis to measure scientific impact and citations in the quest to better understand the research field and also a science mapping to visually represent the scientific research and its development. Our findings suggest that Sustainability is the main journal with published articles on digitalization and sustainability, whereas China has the largest number of papers in the field and collaborations between countries. Finally, by applying Natural Language Processing, we identified as best topics: digital, sustainable, development, sustainability, digitalization, study, research, transformation, innovation, and model. Moreover, we dug deeper into policy implications to show how these findings could serve policymakers and stakeholders in academia and industry. © 2025 by the authors.","bibliometric analysis; Bibliometrix; digitalization; economic sustainability; pyBibX; Scopus; sustainable development; Web of Science","China; data set; digitization; literature review; policy making; stakeholder; sustainability; Sustainable Development Goal","","","","","","","Brynjolfsson E., McAfee A., The Second Machine Age: Work, Progress, and Prosperity in a Time of Brilliant Technologies, (2014); Brennen J.S., Kreiss D., Digitalization, The International Encyclopedia of Communication Theory and Philosophy, pp. 1-11, (2016); Vrana J., Singh R., Digitization, Digitalization, and Digital Transformation, Handbook of Nondestructive Evaluation 4.0, (2021); Tilson D., Lyytinen K., Sorensen C., Research Commentary: Digital Infrastructures: The Missing IS Research Agenda, Inf. Syst. 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Manuf, 9, pp. 1-21, (2021); D'Adamo I., Di Carlo C., Gastaldi M., Rossi E.N., Uricchio A.F., Economic Performance, Environmental Protection and Social Progress: A Cluster Analysis Comparison towards Sustainable Development, Sustainability, 16, (2024)","M.E. Popescu; The Faculty of Economic Cybernetics, Statistics and Informatics, The Bucharest University of Economic Studies, Bucharest, 15–17 Dorobanti St., Sector 1, 010552, Romania; email: madalina.andreica@csie.ase.ro","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20711050","","","","English","Sustainability","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85219193480" -"Yao X.; Xu Z.; Wang X.; Wang L.; Škare M.","Yao, Xuan (57219672669); Xu, Zeshui (55502698400); Wang, Xinxin (57204520948); Wang, Lina (58922158900); Škare, Marinko (6506322858)","57219672669; 55502698400; 57204520948; 58922158900; 6506322858","ENERGY EFFICIENCY AND COVID-19: A SYSTEMATIC LITERATURE REVIEW AND BIBLIOMETRIC ANALYSIS ON ECONOMIC EFFECTS","2024","Technological and Economic Development of Economy","30","1","","287","311","24","6","10.3846/tede.2023.18726","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186951907&doi=10.3846%2ftede.2023.18726&partnerID=40&md5=53df66b5722b5a2e3c6a116c54fbc6ef","School of Economics and Management, Southeast University, Jiangsu, Nanjing, 211189, China; Business School, Sichuan University, Sichuan, Chengdu, 610065, China; Faculty of Economics & Tourism Dr. Mijo Mirkovic, Juraj Dobrila University of Pula, Preradoviceva 1-1, Pula, 52100, Croatia","Yao X., School of Economics and Management, Southeast University, Jiangsu, Nanjing, 211189, China; Xu Z., School of Economics and Management, Southeast University, Jiangsu, Nanjing, 211189, China, Business School, Sichuan University, Sichuan, Chengdu, 610065, China; Wang X., Business School, Sichuan University, Sichuan, Chengdu, 610065, China; Wang L., School of Economics and Management, Southeast University, Jiangsu, Nanjing, 211189, China; Škare M., Faculty of Economics & Tourism Dr. Mijo Mirkovic, Juraj Dobrila University of Pula, Preradoviceva 1-1, Pula, 52100, Croatia","The Corona Virus Disease 2019 (COVID-19) epidemic has deferred global progress in energy efficiency to a decade-long low, posing a threat to the achievement of international climate goals, and also profoundly affected the development of economics. To gain insight into the research frontiers and hotspots in energy efficiency and COVID-19, a systematic literature review and bibliometric analysis on economic effects are performed with the help of the bibliometric tools VOSviewer and Bibliometrix. This paper selects all the publications retrieved based on the subject terms in the Web of Science core collec-tion. Firstly, this article performs a performance analysis of related publications to present the development and distribution of energy efficiency and COVID-19 from research areas, relevant sources, and influential articles. Afterward, a visual analysis of the literature called science mapping analysis is implemented to display the structural and dynamic organization of knowledge in energy efficiency and COVID-19 research. In the end, detailed discussions of two research hotspots and some theoretical and practical implications are concluded in the systematic literature review and bibliometric analysis findings, which may contribute to further development for researchers in the field of energy efficiency and eventually propel the progress of society and economy in an all-round way. © 2023 The Author(s). Published by Vilnius Gediminas Technical University.","COVID-19; energy consumption; energy efficiency; energy policies; science mapping","","","","","","National Natural Science Foundation of China, NSFC, (71971119, 72071135); Scientific Research Foundation of the Graduate School of Southeast University, (YBPY2034)","The study is supported by the National Natural Science Foundation of China (Nos. 72071135, 71971119), and the Scientific Research Foundation of Graduate School of Southeast University (No. YBPY2034).","Abu-Rayash A., Dincer I., Analysis of mobility trends during the COVID-19 coronavirus pan-demic: Exploring global aviation and travel impacts in selected cities, Energy Research & Social Sci-Ence, 68, (2020); Anderson C., The long tail, Wired Magazine, 12, 10, pp. 170-177, (2004); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aruga K., Islam M.M., Jannat A., Effects of COVID-19 on Indian energy consumption, Sustain-Ability, 12, 14, (2020); 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Atomistic insights into the inhibitory mechanisms, Biochemistry, 59, 18, pp. 1769-1779, (2020); Ouyang X.L., Chen J.Q., Du K.R., Energy efficiency performance of the industrial sector: Frothe perspective of technological gap in different regions in China, Energy, 214, (2021); Patterson M.G., What is energy efficiency?, Concepts, Indicators and Methodological Issueenergy Policy, 24, 5, pp. 377-390, (1996); Qin Y., Wang X.X., Xu Z.S., Skare M., The impact of poverty cycles on economic research: Evidence from econometric analysis, Economic Research-Ekonomska Istraživanja, 34, 1, pp. 152-171, (2021); Small H., Co-citation in the scientific literature: A new measure of the relationship between twdocuments, Journal of the American Society for Information Science, 24, 4, pp. 265-269, (1973); Sovacool B.K., Furszyfer Del Rio D., Griffiths S., Contextualizing the Covid-19 pandemic for a carbon-constrained world: Insights for sustainability transitions, energy justice, and research meth-odology, Energy Research & Social Science, 68, (2020); Trianni A., Merigo J.M., Bertoldi P., Ten Years of Energy Efficiency: A Bibliometric Analysenergy Efficiency, 11, 8, pp. 1917-1939, (2018); van Doremalen N., Bushmaker T., Morris D.H., Holbrook M.G., Gamble A., Williamson B.N., Tamin A., Harcourt J.L., Thornburg N.J., Gerber S.I., Lloyd-Smith J.O., de Wit E., Munster V.J., Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1, New England Journal of Medicine, 382, 16, pp. 1564-1567, (2020); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Wang N., Zhu Y.M., Yang T.B., The impact of transportation infrastructure and industrial agglomeration on energy efficiency: Evidence from China’s industrial sectors, Journal of Cleaner Production, 244, (2020); Wang X.X., Xu Z.S., Skare M., A bibliometric analysis of Economic Research-Ekonomska Istraživanja (2007–2019), Economic Research-Ekonomska Istraživanja, 33, 1, pp. 865-886, (2020); Wang X.X., Xu Z.S., Su S., Zhou W., A comprehensive bibliometric analysis of uncertain group decision making from 1980 to 2019, Information Sciences, 547, pp. 328-353, (2021); Worrell E., Bernstein L., Roy J., Price L., Harnisch J., Industrial energy efficiency and climachange mitigation, Energy Efficiency, 2, 2, pp. 109-123, (2008); Xu Z.S., Ge Z.J., Wang X.X., Skare M., Bibliometric analysis of technology adoption literature published from 1997 to 2020, Technological Forecasting and Social Change, 170, (2021); Xu Z.S., Wang X.D., Wang X.X., Skare M., A comprehensive bibliometric analysis of entrepre-neurship and crisis literature published from 1984 to 2020, Journal of Business Research, 135, pp. 304-318, (2021); Yu D.J., He X.R., A bibliometric study for DEA applied to energy efficiency: Trends and futuchallenges, Applied Energy, 268, (2020); Yu D.J., Kou G., Xu Z.S., Shi S.S., Analysis of collaboration evolution in AHP research: 1982– 2018, International Journal of Information Technology & Decision Making, 20, 1, pp. 7-36, (2021); Yu Y.T., Luo N.S., Does urbanization improve energy efficiency?, Empirical Evidence from Chintechnological and Economic Development of Economy, 28, 4, pp. 1003-1021, (2022); Zhang D.D., Li H.Y., Zhu H.Y., Zhang H.C., Goh H.H., Wong M.C., Wu T., Impact of CO-VID-19 on urban energy consumption of commercial tourism city, Sustainable Cities and Society, 73, (2021); Zhang L.Y., Li H., Lee W., Liao H., COVID-19 and energy: Influence mechanisms and researcmethodologies, Sustainable Production and Consumption, 27, pp. 2134-2152, (2021)","M. Škare; Faculty of Economics & Tourism Dr. Mijo Mirkovic, Juraj Dobrila University of Pula, Pula, Preradoviceva 1-1, 52100, Croatia; email: mskare@unipu.hr","","Vilnius Gediminas Technical University","","","","","","20294913","","","","English","Technol. Econ. Develop. Econ.","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85186951907" -"Sharma M.; Srivastava R.","Sharma, Meenakshi (59936869200); Srivastava, Rajeev (57221637321)","59936869200; 57221637321","The previous and future trend of social media marketing research: a bibliometric analysis","2025","International Journal of Electronic Marketing and Retailing","16","3","","269","291","22","0","10.1504/IJEMR.2025.146174","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105004940130&doi=10.1504%2fIJEMR.2025.146174&partnerID=40&md5=c2bef94cecada78e12df55397a9a4de3","University of Petroleum and Energy Studies, Kandoli Campus, Dehradun, India; IMS Unison University, Dehradun, India","Sharma M., University of Petroleum and Energy Studies, Kandoli Campus, Dehradun, India; Srivastava R., IMS Unison University, Dehradun, India","Marketers are tailoring their strategies to embrace the significant advantage of social media interaction. Considering the value of social media marketing in the corporate world and academic publication, it is necessary to understand the research trend of this field and to understand the future research directions in this field. The aim of this research is to examine the research landscape of the social media marketing field by using comprehensive bibliometric analysis. A total of 768 documents taken from the reputed database namely Web of Science (WoS) published within the last 12 years. The study will help to know the trend of publication, the top articles contributed in terms of journals, scholars, citations, and impact factors. It will also help to identify the trending topics relevant to authors, affiliations, and countries that have made contributions to the field of social media marketing and help young scholars to identify the conceptual structure of the topic as presented along with the social network structure of a particular scientific community, build a scope of additional research in this field and assist the marketers and practitioners to make decisions and build effective social media marketing strategies for customer acquisition towards sustainable business in this new digital age. Copyright © 2025 Inderscience Enterprises Ltd.","bibliometric analysis; bibliometrix; biblioshiny; performance analysis; research trends; science mapping; social media marketing","","","","","","","","Abbas M.J., Khalil L.S., Haikal A., Dash M.E., Dongmo G., Okoroha K.R., Eliciting emotion and action increases social media engagement: an analysis of influential orthopaedic surgeons, Arthroscopy, Sports Medicine, and Rehabilitation, 3, 5, pp. e1301-e1308, (2021); Alhakimi W., Alwadhan R., Social media and the decision-making process: empirical evidence from Yemen, International Journal of Electronic Marketing and Retailing, 12, 2, pp. 133-155, (2021); Ananda A.S., Hernandez-Garcia A., Lamberti L., N-REL: a comprehensive framework of social media marketing strategic actions for marketing organizations, Journal of Innovation and Knowledge, 1, 3, pp. 170-180, (2016); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, J. Inform, 11, pp. 959-975, (2017); Ashley C., Tuten T., Creative strategies in social media marketing: an exploratory study of branded social content and consumer engagement, Psychology and Marketing, 32, 1, pp. 15-27, (2015); Bahuguna P.C., Srivastava R., Tiwari S., Two-decade journey of green human resource management research: a bibliometric analysis, Benchmarking: An International Journal, 30, 2, pp. 585-602, (2022); Balakrishnan B.K.P.D., Dahnil M.I., Yi W.J., The impact of social media marketing medium toward purchase intention and brand loyalty among generation Y, Procedia - Social and Behavioral Sciences, 148, pp. 177-185, (2014); Bartschat M., Cziehso G., Hennig-Thurau T., Searching for word of mouth in the digital age: Determinants of consumers’ uses of face-to-face information, internet opinion sites, and social media, Journal of Business Research, 141, pp. 393-409, (2022); Callon M., Courtial J-P., Turner W.A., Bauin S., From translations to problematic networks: an introduction to co-word analysis, Social Science Information, 22, pp. 191-235, (1983); Chan N.L., Guillet B.D., Investigation of social media marketing: how does the hotel industry in Hong Kong perform in marketing on social media websites?, Journal of Travel and Tourism Marketing, 28, 4, pp. 345-368, (2011); Chawla Y., Chodak G., Social media marketing for businesses: organic promotions of web-links on Facebook, Journal of Business Research, 135, pp. 49-65, (2021); Chen C.W., Lien N.H., Social media and marketing effectiveness, Asia Pacific Management Review, 22, 1, (2017); Constantinides E., Foundations of social media marketing, Procedia - Social and Behavioral Sciences, 148, pp. 40-57, (2014); Cvijikj P.I., Michahelles F., Online engagement factors on Facebook brand pages, Social Network Analysis and Mining, 3, 4, pp. 843-861, (2013); Dahnil M.I., Marzuki K.M., Langgat J., Fabeil N.F., Factors influencing SMEs adoption of social media marketing, Procedia - Social and Behavioral Sciences, 148, pp. 119-126, (2014); De Veirman M., Cauberghe V., Hudders L., Marketing through Instagram influencers: the impact of number of followers and product divergence on brand attitude, International Journal of Advertising, 36, 5, pp. 798-828, (2017); De Vries L., Gensler S., Leeflang P.S., Popularity of brand posts on brand fan pages: an investigation of the effects of social media marketing, Journal of Interactive Marketing, 26, 2, pp. 83-91, (2012); Dwivedi Y.K., Ismagilova E., Hughes D.L., Carlson J., Filieri R., Jacobson J., Jain V., Karjaluoto H., Kefi H., Krishen A.S., Kumar V., Rahman M.M., Raman R., Rauschnabel P.A., Rowley J., Salo J., Tran G.A., Wang Y., Setting the future of digital and social media marketing research: perspectives and research propositions, International Journal of Information Management, 59, (2021); Enli G.S., Skogerbo E., Personalized campaigns in party-centred politics: Twitter and Facebook as arenas for political communication, Information, Communication and Society, 16, 5, pp. 757-774, (2013); Erdogmus I.E., Cicek M., The impact of social media marketing on brand loyalty, Procedia - Social and Behavioral Sciences, 58, pp. 1353-1360, (2012); Eslami S.P., Ghasemaghaei M., Hassanein K., Understanding consumer engagement in social media: the role of product lifecycle, Decision Support Systems, (2021); Faruk M., Rahman M., Hasan S., How digital marketing evolved over time: a bibliometric analysis on scopus database, Heliyon, 7, 12, (2021); Felix R., Rauschnabel P.A., Hinsch C., Elements of strategic social media marketing: a holistic framework, Journal of Business Research, 70, pp. 118-126, (2017); Fink M., Koller M., Gartner J., Floh A., Harms R., Effective entrepreneurial marketing on Facebook – a longitudinal study, Journal of Business Research, 113, pp. 149-157, (2020); Firdaus R.B.R., Gunaratne M.S., Rahmat S.R., Kamsi N.S., Does climate change only affect food availability? What else matters?, Cogent Food & Agriculture, 5, 1, (2019); Gartner J., Fink M., Floh A., Eggers F., Service quality in social media communication of NPOs: the moderating effect of channel choice, Journal of Business Research, 137, pp. 579-587, (2021); Godey B., Manthiou A., Pederzoli D., Rokka J., Aiello G., Donvito R., Singh R., Social media marketing efforts of luxury brands: influence on brand equity and consumer behavior, Journal of Business Research, 69, 12, pp. 5833-5841, (2016); Gross M., Differences between mobile and non-mobile buyers: comparing attitudinal, motive-related, and media behaviour, International Journal of Electronic Marketing and Retailing, 11, 1, pp. 50-80, (2020); Hagen D., Risselada A., Spierings B., Weltevreden J.W.J., Atzema O., Digital marketing activities by Dutch place management partnerships: a resource-based view, Cities, 123, (2022); Haverila M.J., Haverila K., McLaughlin C., The moderating role of relationship quality in the customer engagement and satisfaction relationship in brand communities: the role of gender, International Journal of Electronic Marketing and Retailing, 12, 4, pp. 339-356, (2021); Hays S., Page S.J., Buhalis D., Social media as a destination marketing tool: its use by national tourism organisations, Current issues in Tourism, 16, 3, pp. 211-239, (2013); Hoffman D.L., Fodor M., Can you measure the ROI of your social media marketing?, MIT Sloan Management Review, 52, 1, (2010); Howells K., Ertugan A., Applying fuzzy logic for sentiment analysis of social media network data in marketing, Procedia Computer Science, 120, pp. 664-670, (2017); Jacobson J., Gruzd A., Hernandez-Garcia A., Social media marketing: who is watching the watchers?, Journal of Retailing and Consumer Services, 53, (2020); Juntunen M., Ismagilova E., Oikarinen E.L., B2B brands on Twitter: engaging users with a varying combination of social media content objectives, strategies, and tactics, Industrial Marketing Management, 89, pp. 630-641, (2020); Kamboj S., Yadav M., Rahman Z., Impact of social media and customer-centric technology on performance outcomes: the mediating role of social CRM capabilities, International Journal of Electronic Marketing and Retailing, 9, 2, pp. 109-125, (2018); Kim A.J., Ko E., Do social media marketing activities enhance customer equity? An empirical study of luxury fashion brand, Journal of Business Research, 65, 10, pp. 1480-1486, (2012); Kim J., Kim J.E., Johnson K.K., The customer-salesperson relationship and sales effectiveness in luxury fashion stores: the role of self monitoring, Journal of Global Fashion Marketing, 1, 4, pp. 230-239, (2010); Kirtis A.K., Karahan F., To be or not to be in social media arena as the most cost-efficient marketing strategy after the global recession, Procedia - Social and Behavioral Sciences, 24, pp. 260-268, (2011); Kozinets R.V., De Valck K., Wojnicki A.C., Wilner S.J., Networked narratives: understanding word-of-mouth marketing in online communities, Journal of Marketing, 74, 2, pp. 71-89, (2010); Liu Z., Park S., What makes a useful online review? Implication for travel product websites, Tourism Management, 47, pp. 140-151, (2015); Malthouse E.C., Haenlein M., Skiera B., Wege E., Zhang M., Managing customer relationships in the social media era: Introducing the social CRM house, Journal of Interactive Marketing, 27, 4, pp. 270-280, (2013); Marin G.D., Nila C., Branding in social media, using LinkedIn in personal brand communication: a study on communications/marketing and recruitment/human resources specialists perception, Social Sciences and Humanities Open, 4, 1, (2021); Mazerant K., Willemsen L.M., Neijens P.C., van Noort G., Spot-on creativity: creativity biases and their differential effects on consumer responses in (non-)real-time marketing, Journal of Interactive Marketing, 53, pp. 15-31, (2021); Michaelidou N., Siamagka N.T., Christodoulides G., Usage, barriers and measurement of social media marketing: an exploratory investigation of small and medium B2B brands, Industrial Marketing Management, 40, 7, pp. 1153-1159, (2011); Narayanaswamy R., Heiens R., The impact of digital sales channels on web sales: evidence from the USA’s largest online retailers, International Journal of Electronic Marketing and Retailing, 12, 3, pp. 306-322, (2021); Obermayer N., Kovari E., Leinonen J., Bak G., Valeri M., How social media practices shape family business performance: the wine industry case study, European Management Journal, (2021); Oztamur D., Karakadilar I.S., Exploring the role of social media for SMEs: as a new marketing strategy tool for the firm performance perspective, Procedia - Social and Behavioral Sciences, 150, pp. 511-520, (2014); Pantano E., When a luxury brand bursts: modelling the social media viral effects of negative stereotypes adoption leading to brand hate, Journal of Business Research, 123, pp. 117-125, (2021); Reinikainen H., Tan T.M., Luoma-aho V., Salo J., Making and breaking relationships on social media: the impacts of brand and influencer betrayals, Technological Forecasting and Social Change, 171, (2021); Rishika R., Kumar A., Janakiraman R., Bezawada R., The effect of customers’ social media participation on customer visit frequency and profitability: an empirical investigation, Information Systems Research, 24, 1, pp. 108-127, (2013); Roy D., Srivastava R., Jat M., Karaca M.S., A complete overview of analytics techniques: descriptive, predictive, and prescriptive, Decision Intelligence Analytics and the Implementation of Strategic Business Management, pp. 15-30, (2022); Saheb T., Amini B., Kiaei Alamdari F., Quantitative analysis of the development of digital marketing field: Bibliometric analysis and network mapping, International Journal of Information Management Data Insights, 1, 2, (2021); Sangwan S., Sharma S., Social media communication and consumer decision making: an empirical perspective, International Journal of Electronic Marketing and Retailing (IJEMR), 13, 4, (2022); Schoner-Schatz L., Hofmann V., Stokburger-Sauer N.E., Destination’s social media communication and emotions: an investigation of visit intentions, word-of-mouth and travelers’ facially expressed emotions, Journal of Destination Marketing and Management, 22, (2021); Sharma M., Chaubey D.S., An empirical study of customer experience and its relationship with customer satisfaction towards the services of banking sector, Journal of Marketing and Communication, 9, 3, pp. 18-27, (2014); Sharma M., Kumar R., Chauhan P., COVID-19 turbulence and positive shifts in online purchasing by consumers: modeling the enablers using ISM- MICMAC analysis, Journal of Global Operations and Strategic Sourcing, (2022); Sharma M., Tiwari P., Chaubey D.S., Summarizing factors of customer experience and building a structural model using total interpretive structural modelling technology, Global Business Review, 17, 3, pp. 730-741, (2016); Smith A.N., Fischer E., Yongjian C., How does brand-related user-generated content differ across YouTube, Facebook, and Twitter?, Journal of Interactive Marketing, 26, 2, pp. 102-113, (2012); Srivastava R., Et al., Towards a model for effective e-waste management: a study of software industry in India, International Journal of Environment and Waste Management, 27, 1, pp. 61-73, (2021); Stallone V., Wetzels M., Klaas M., Applications of blockchain technology in marketing–a systematic review of marketing technology companies, Blockchain: Research and Applications, 2, 3, (2021); Tandon A., Dhir A., Talwar S., Kaur P., Mantymaki M., Dark consequences of social media-induced fear of missing out (FoMO): Social media stalking, comparisons, and fatigue, Technological Forecasting and Social Change, 171, (2021); Vance K., Howe W., Dellavalle RP Social internet sites as a source of public health information, Dermatol Clin, 27, 2, pp. 133-136, (2009); Vrontis D., Siachou E., Sakka G., Chatterjee S., Chaudhuri R., Ghosh A., Societal effects of social media in organizations: reflective points deriving from a systematic literature review and a bibliometric meta-analysis, European Management Journal, (2022); Waltman L., A review of the literature on citation impact indicators, Journal of Informetrics, 10, 2, pp. 365-391, (2016); Weismayer C., Gunter U., Onder I., Temporal variability of emotions in social media posts, Technological Forecasting and Social Change, 167, (2021); Widmar N., Bir C., Wolf C., Lai J., Liu Y., #Eggs: social and online media-derived perceptions of egg-laying hen housing, Poultry Science, 99, 11, pp. 5697-5706, (2020); Yu Y., Duan W., Cao Q., The impact of social and conventional media on firm equity value: a sentiment analysis approach, Decision Support Systems, 55, 4, pp. 919-926, (2013)","M. Sharma; University of Petroleum and Energy Studies, Dehradun, Kandoli Campus, India; email: meenakshiraj29@rediffmail.com","","Inderscience Publishers","","","","","","17411025","","","","English","Int. J. Electron. Mark. Retail.","Article","Final","","Scopus","2-s2.0-105004940130" -"Solis Pino A.F.; Ruiz P.H.; Agredo-Delgado V.; Mon A.; Collazos C.A.","Solis Pino, Andrés Felipe (57567174100); Ruiz, Pablo H. (56100326900); Agredo-Delgado, Vanessa (57195069921); Mon, Alicia (55838067200); Collazos, Cesar Alberto (8568805300)","57567174100; 56100326900; 57195069921; 55838067200; 8568805300","Human-Computer Interaction Research in Ibero-America: A Bibliometric Analysis","2024","Communications in Computer and Information Science","1877 CCIS","","","185","199","14","0","10.1007/978-3-031-57982-0_15","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192363787&doi=10.1007%2f978-3-031-57982-0_15&partnerID=40&md5=60bd593ea7b94ae525edbc340980acc3","Universidad del Cauca, Calle 5 N.º 4-70, Cauca, Popayán, 190003, Colombia; Corporación Universitaria Comfacauca - Unicomfacauca, Cl 4 N° 8-30 Centro Histórico, Cauca, Popayán, 190001, Colombia; Universidad Nacional de La Matanza, Florencio Varela 1903 (B1754JEC), Buenos Aires, San Justo, 1754, Argentina","Solis Pino A.F., Universidad del Cauca, Calle 5 N.º 4-70, Cauca, Popayán, 190003, Colombia, Corporación Universitaria Comfacauca - Unicomfacauca, Cl 4 N° 8-30 Centro Histórico, Cauca, Popayán, 190001, Colombia; Ruiz P.H., Corporación Universitaria Comfacauca - Unicomfacauca, Cl 4 N° 8-30 Centro Histórico, Cauca, Popayán, 190001, Colombia; Agredo-Delgado V., Corporación Universitaria Comfacauca - Unicomfacauca, Cl 4 N° 8-30 Centro Histórico, Cauca, Popayán, 190001, Colombia; Mon A., Universidad Nacional de La Matanza, Florencio Varela 1903 (B1754JEC), Buenos Aires, San Justo, 1754, Argentina; Collazos C.A., Universidad del Cauca, Calle 5 N.º 4-70, Cauca, Popayán, 190003, Colombia","Human-computer interaction is a globally significant multidisciplinary field to enhance the usability of electronic devices for work, entertainment, and educational activities about human beings. Within the Ibero-American region, a community of researchers specializing in Human-computer interaction and related interdisciplinary domains has been established. Hence, it is crucial to understand this field’s current state and evolution to identify critical contributors, institutions, information sources, and knowledge networks. This knowledge enables the contextualization of research, project planning, resource management, and improved dissemination within the domain. This study employed the Science Mapping Workflow methodology and specialized tools like Bibliometrix to conduct a bibliometric analysis of Human-computer interaction in Ibero-America. The findings reveal that the domain is well-established at the Ibero-American level and exhibits a growth rate of 14.65% in publications, indicating consistent progress. Moreover, Spain and Brazil have emerged as leading contributors in this field. Regarding the knowledge structure, it is evident that numerous technological advancements are focused on enhancing the capabilities of individuals with disabilities or limitations. Furthermore, video games, computer-mediated communication, natural interfaces, and artificial intelligence are identified as prominent trends within Human-computer interaction. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.","Bibliometric Analysis; Human-Computer Interaction; Ibero-America","Computer games; Growth rate; 'current; Bibliometrics analysis; Educational activities; Electronics devices; Human being; Human-computer interaction researches; Ibero-america; Information sources; Knowledge networks; Work activities; Human computer interaction","","","","","","","Gupta N., An overview on human-computer interaction, Asian J. Multidimens. 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Solis Pino; Universidad del Cauca, Popayán, Calle 5 N.º 4-70, Cauca, 190003, Colombia; email: afsolis@unicauca.edu.co","Ruiz P.H.; Agredo-Delgado V.; Agredo-Delgado V.; Mon A.","Springer Science and Business Media Deutschland GmbH","","9th Iberoamerican Workshop, HCI-COLLAB 2023, Buenos Aires, Argentina, September 13–15, 2023, Revised Selected Papers","13 September 2023 through 15 September 2023","Buenos Aires","311519","18650929","978-303157981-3","","","English","Commun. Comput. Info. Sci.","Conference paper","Final","","Scopus","2-s2.0-85192363787" -"Hermaputi R.L.; Hua C.","Hermaputi, Roosmayri Lovina (57224952582); Hua, Chen (15622897300)","57224952582; 15622897300","Unveiling the Trajectories and Trends in Women-Inclusive City Related Studies: Insights from a Bibliometric Exploration","2024","Land","13","6","852","","","","0","10.3390/land13060852","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197219965&doi=10.3390%2fland13060852&partnerID=40&md5=bcc75f9cf38e21f892f3ccdf9d7e37a8","College of Civil Engineering and Architecture, Zhejiang University, Hangzhou, 310058, China; Center for Balance Architecture, Zhejiang University, Hangzhou, 310058, China","Hermaputi R.L., College of Civil Engineering and Architecture, Zhejiang University, Hangzhou, 310058, China; Hua C., College of Civil Engineering and Architecture, Zhejiang University, Hangzhou, 310058, China, Center for Balance Architecture, Zhejiang University, Hangzhou, 310058, China","Despite the ongoing discrimination that hinders women’s full participation in urban life, the International Agenda 2030 and its Sustainable Development Goals (SDGs) emphasize the eradication of violence against women and underscore the need for regulatory measures, local governance, and equitable practices for sustainable urban development focusing on women’s needs. The women-inclusive cities related (WICR) studies, which have been gaining academic attention since the late 1990s, remain broadly explored yet lack a holistic trajectory and trend study and a precise women-inclusive city concept framework. This study applies bibliometric analysis with R-package Bibliometrix version 3.3.2 and a systematic review of 1144 articles, mapping global trends and providing a framework for women-inclusive city concepts. The findings show that WICR research increased significantly from 1998 to 2022, indicating continuous interest. Gender, women, and politics are the top three most frequent keywords. Emerging research directions are expected to focus on politics, violence, and urban governance. The findings also indicate a clear tendency for researchers from the same geographical backgrounds or regions to co-author papers, suggesting further international collaboration. Although no explicit definitions were found in the articles used, the prevailing literature consistently suggests that a “woman-inclusive city” ensures full rights, equal consideration of needs, and the active participation of women in all aspects of urban life. © 2024 by the authors.","bibliometric analysis; Bibliometrix; feminist urbanism; science mapping; urban equity; women-inclusive cities","holistic approach; Sustainable Development Goal; urban development; violence; womens status","","","","","","","Progress of the World’s Women 2019–2020: Families in a Changing World, (2019); Bird S.R., Sapp S.G., Understanding the Gender Gap in Small Business Success: Urban and Rural Comparisons, Gend. Soc, 18, pp. 5-28, (2004); Katz M.B., Stern M.J., Fader J.J., Women and the Paradox of Economic Inequality in the Twentieth-Century, J. Soc. Hist, 39, pp. 65-88, (2005); Making Space: Women and the Man-Made Environment, (1984); Carrera L., Castellaneta M., Women and Cities. 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Development, Urban Geogr, 40, pp. 1148-1167, (2019); Boren T., Grzys P., Young C., Policy-Making as an Emotionally-Charged Arena: The Emotional Geographies of Urban Cultural Policy-Making, Int. J. Cult. Policy, 27, pp. 449-462, (2021); Castro M., The Gendered (Di)-Vision of the Rebellion: The Public and the Private in Life Histories of Female and Male Union Leaders, Salvador-Bahia-Brazil, Identities-Glob. Stud. Cult. Power, 5, pp. 65-96, (1998); Elwood S., Digital Geographies, Feminist Relationality, Black and Queer Code Studies: Thriving Otherwise, Prog. Hum. Geogr, 45, pp. 209-228, (2021); Nanditha N., Exclusion in #MeToo India: Rethinking Inclusivity and Intersectionality in Indian Digital Feminist Movements, Fem. Media Stud, 22, pp. 1673-1694, (2022); Houngbonon G.V., Le Quentrec E., Rubrichi S., Access to Electricity and Digital Inclusion: Evidence from Mobile Call Detail Records, Humanit. Soc. Sci. Commun, 8, (2021); Abubakar N.H., Kah M.M.O., Mobile Phones and Social Inclusion of Women in Africa: A Nigerian Perspective, Afr. J. Inf. Syst, 13, pp. 241-258, (2021)","R.L. Hermaputi; College of Civil Engineering and Architecture, Zhejiang University, Hangzhou, 310058, China; email: 12012149@zju.edu.cn","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","2073445X","","","","English","Land","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85197219965" -"Singh J.; Sehgal S.","Singh, Jaspal (57215131043); Sehgal, Shivam (59013511200)","57215131043; 59013511200","Bibliometric Analysis of Emerging Bond Market Research: Performance Insights and Science Mapping","2024","Eurasian Journal of Business and Economics","17","33","","133","154","21","0","10.17015/ejbe.2024.033.07","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85195698150&doi=10.17015%2fejbe.2024.033.07&partnerID=40&md5=165f84606e44c5f99f57d461e4e2b44b","Guru Nanak Dev University, India","Singh J., Guru Nanak Dev University, India; Sehgal S., Guru Nanak Dev University, India","This bibliometric paper investigates the research landscape in emerging bond market literature, spanning 1993 to 2023, and encompasses a total of 325 research articles. Employing a multifaceted approach, it begins by examining publication trends, core journals, prominent authors, influential articles, and keyword dynamics, providing a comprehensive overview of research dynamics in this domain. Beyond performance analysis, the study ventures into science mapping using co-word analysis to uncover the underlying conceptual structure of the emerging bond market field. The bibliographic data has been drawn from Scopus and analyzed using the Bibliometrix R package, providing insights into the current dimensions of emerging bond market studies. This analysis facilitated the identification of five major keyword clusters, i.e., sovereign bonds, the impact of financial crises, yield curve, corporate bonds, and Islamic bonds in the emerging bond market space. Based on these themes, the study also suggests avenues for future scholarly exploration in this specialized field. © 2024 Ala-Too International University.","Bibliometric analysis; Conceptual structure; Emerging Bond markets; Performance Insights; Science mapping","","","","","","","","Ahi E., Akgiray V., Sener E., Robust term structure estimation in developed and emerging markets, Annals of Operations Research, 260, 1–2, pp. 23-49, (2018); Aktug R. E., Vasconcellos G., Bae Y., The dynamics of sovereign credit default swap and bond markets: Empirical evidence from the 2001 to 2007 period, Applied Economics Letters, 19, 3, pp. 251-259, (2012); Apostolou A., Beirne J., Volatility spillovers of unconventional monetary policy to emerging market economies, Economic Modelling, 79, pp. 118-129, (2019); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Azis I. J., Virananda I. G. S., Estiko F. I., Financial spillover in emerging asia: A tale of three crises, Asian Economic Papers, 20, 2, pp. 156-170, (2021); Balli F., Hu X., Rana F., Bond market integration of emerging economies and bilateral linkages, Accounting and Finance, 60, 3, pp. 2039-2062, (2020); Banga J., The green bond market: A potential source of climate finance for developing countries, Journal of Sustainable Finance & Investment, 9, 1, pp. 17-32, (2019); Bhuiyan R. A., Rahman M. P., Saiti B., Mat Ghani G., Financial integration between sukuk and bond indices of emerging markets: Insights from wavelet coherence and multivariate-GARCH analysis, Borsa Istanbul Review, 18, 3, pp. 218-230, (2018); Bhuiyan R. A., Rahman M. P., Saiti B., Mat Ghani G., Co-movement dynamics between global sukuk and bond markets, International Journal of Emerging Markets, 14, 4, pp. 550-581, (2019); Blondel V. D., Guillaume J.-L., Lambiotte R., Lefebvre E., Fast unfolding of communities in large networks, Journal of Statistical Mechanics: Theory and Experiment, 2008, 10, (2008); Borner K., Chen C., Boyack K. W., Visualizing knowledge domains, Annual Review of Information Science and Technology, 37, 1, pp. 179-255, (2003); Bradford S. C., Sources of information on specific subjects, Engineering, 137, pp. 85-86, (1934); Cepni O., Guney I. E., Kucuksarac D., Hasan Yilmaz M., Do local and global factors impact the emerging markets’ sovereign yield curves? Evidence from a data-rich environment, Journal of Forecasting, (2021); Chen J., Yang L., A Bibliometric Review of Volatility Spillovers in Financial Markets: Knowledge Bases and Research Fronts, Emerging Markets Finance and Trade, 57, 5, pp. 1358-1379, (2021); Christensen J. H. E., Fischer E., Shultz P. J., Bond flows and liquidity: Do foreigners matter?, Journal of International Money and Finance, 117, (2021); Corbet S., Dowling M., Gao X., Huang S., Lucey B., Vigne S. A., An analysis of the intellectual structure of research on the financial economics of precious metals, Resources Policy, 63, (2019); Dimic N., Piljak V., Swinkels L., Vulanovic M., The structure and degree of dependence in government bond markets, Journal of International Financial Markets, Institutions and Money, 74, (2021); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Gairola G., Dey K., Price discovery and risk management in asset class: A bibliometric analysis and research agenda, Applied Economics Letters, 30, 17, pp. 2320-2331, (2023); Garcia Lopez G. I., Stracca L., Changing patterns of capital flows, (2021); Hassan M. K., Ngene G. M., Yu J.-S., Credit default swaps and sovereign debt markets, Economic Systems, 39, 2, pp. 240-252, (2015); Hassan M. K., Paltrinieri A., Dreassi A., Miani S., Sclip A., The determinants of co-movement dynamics between sukuk and conventional bonds, Quarterly Review of Economics and Finance, 68, pp. 73-84, (2018); Inaba K.-I., An empirical illustration of the integration of sovereign bond markets, Journal of Multinational Financial Management, 61, (2021); Jalal R. N.-U.-D., Alon I., Paltrinieri A., A bibliometric review of cryptocurrencies as a financial asset, Technology Analysis & Strategic Management, pp. 1-16, (2021); Kearns J., Schrimpf A., Xia F. D., Explaining Monetary Spillovers: The Matrix Reloaded, Journal of Money, Credit and Banking, 55, 6, pp. 1535-1568, (2023); Kenourgios D., Naifar N., Dimitriou D., Islamic financial markets and global crises: Contagion or decoupling?, Economic Modelling, 57, pp. 36-46, (2016); Kenourgios D., Padhi P., Emerging markets and financial crises: Regional, global or isolated shocks?, Journal of Multinational Financial Management, 22, 1, pp. 24-38, (2012); Khalid A., Ahmad Z., Stock–bond co-movement in ASEAN-5: The role of financial integration and financial development, International Journal of Emerging Markets, 18, 5, pp. 1033-1052, (2023); Knopf J. W., Doing a Literature Review, PS: Political Science & Politics, 39, 1, pp. 127-132, (2006); Kumar G., Choudhary K., Behavioural Finance: A Review of Major Research Themes and Bibliometric Analysis, Eurasian Journal of Business and Economics, 16, 32, pp. 1-22, (2023); Kumar S., Sharma D., Rao S., Lim W. M., Mangla S. K., Past, present, and future of sustainable finance: Insights from big data analytics through machine learning of scholarly research, Annals of Operations Research, pp. 1-44, (2022); Li L., Scrimgeour F., The co-integration of CDS and bonds in time-varying volatility dynamics: Do credit risk swaps lower bond risks?, Studies in Nonlinear Dynamics and Econometrics, (2021); Lin L.-W., Milhaupt C. J., Bonded to the state: A network perspective on China’s corporate debt market, Journal of Financial Regulation, 3, 2, pp. 1-39, (2017); MacDonald M., International capital market frictions and spillovers from quantitative easing, Journal of International Money and Finance, 70, pp. 135-156, (2017); Mbarek L., Marfatia H. 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Government bond investors and microeconomic policy changes, Economics and Politics, 32, 2, pp. 197-249, (2020); Nagy K., Term structure estimation with missing data: Application for emerging markets, Quarterly Review of Economics and Finance, 75, pp. 347-360, (2020); Naqvi N., Manias, Panics and Crashes in Emerging Markets: An Empirical Investigation of the Post-2008 Crisis Period, New Political Economy, 24, 6, pp. 759-779, (2019); Nisha, Puri N., Rajput N., Singh H., Foundations and trends in option pricing models: A 45 years global examination based on bibliometric analysis, Qualitative Research in Financial Markets, (2024); Ozbek I., Talasli I., Term premium in emerging market sovereign yields: Role of common and country specific factors, Central Bank Review, 20, 4, pp. 169-182, (2020); Paul J., Lim W. M., O'Cass A., Hao A. W., Bresciani S., Scientific procedures and rationales for systematic literature reviews (SPAR-4-SLR), International Journal of Consumer Studies, 45, 4, pp. O1-O16, (2021); Paweenawat A., The Information Content of the Term Structure of Interest Rates in Emerging Economies: The Case of Thailand, Journal of Emerging Market Finance, 16, 2, pp. 136-150, (2017); Phulwani P. R., Kumar D., Goyal P., A Systematic Literature Review and Bibliometric Analysis of Recycling Behavior, Journal of Global Marketing, 33, 5, pp. 354-376, (2020); Qin W., Cho S., Hyde S., Time-varying bond market integration and the impact of financial crises, International Review of Financial Analysis, 90, (2023); Raja Z. A., Procasky W. J., Oyotode-Adebile R., The Relative Role of Sovereign CDS and Bond Markets in Efficiently Pricing Emerging Market Sovereign Credit Risk, Journal of Emerging Market Finance, 19, 3, pp. 296-325, (2020); Rhee S. G., The emerging bond markets of South-east Asia. Organisation for Economic Cooperation and Development, The OECD Observer, 181, (1993); Schweizer D., Walker T., Zhang A., False hopes and blind beliefs: How political connections affect China’s corporate bond market, Journal of Banking and Finance, (2021); Sowmya S., Prasanna K., Yield curve interactions with the macroeconomic factors during global financial crisis among Asian markets, International Review of Economics & Finance, 54, pp. 178-192, (2018); Tranfield D., Denyer D., Smart P., Towards a Methodology for Developing Evidence-Informed Management Knowledge by Means of Systematic Review, British Journal of Management, 14, 3, pp. 207-222, (2003); Tsang A., Yiu M. S., Nguyen H. T., Spillover across sovereign bond markets between the US and ASEAN4 economies, Journal of Asian Economics, 76, (2021); Vogel R., Guttel W. H., The Dynamic Capability View in Strategic Management: A Bibliometric Review, International Journal of Management Reviews, 15, 4, pp. 426-446, (2013); Walker T., Zhang X., Zhang A., Wang Y., Fact or fiction: Implicit government guarantees in China’s corporate bond market, Journal of International Money and Finance, 116, (2021); Zaremba A., Kizys R., Aharon D. Y., Umar Z., Term spreads and the COVID-19 pandemic: Evidence from international sovereign bond markets, Finance Research Letters, (2021); Zhang J., Yu Q., Zheng F., Long C., Lu Z., Duan Z., Comparing keywords plus of WOS and author keywords: A case study of patient adherence research, Journal of the Association for Information Science and Technology, 67, 4, pp. 967-972, (2016); Zupic I., Cater T., Bibliometric Methods in Management and Organization, Organizational Research Methods, 18, 3, pp. 429-472, (2014)","S. Sehgal; Guru Nanak Dev University, India; email: shivamusfs.rsh@gndu.ac.in","","Ala-Too International University","","","","","","16945948","","","","English","Eurasian J. Bus. Econ.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85195698150" -"Ettadili H.; Vural C.","Ettadili, Hamza (58828138400); Vural, Caner (35226847000)","58828138400; 35226847000","Bibliometric Analysis and Network Visualization of Nanozymes for Microbial Theranostics in the Last Decade","2025","Applied Biochemistry and Biotechnology","197","3","113241","1923","1945","22","1","10.1007/s12010-024-05120-0","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85211463598&doi=10.1007%2fs12010-024-05120-0&partnerID=40&md5=280df8f0920f84d74a508a92a096b230","Faculty of Science, Department of Biology, Molecular Biology Section, Pamukkale University, Denizli, 20160, Turkey","Ettadili H., Faculty of Science, Department of Biology, Molecular Biology Section, Pamukkale University, Denizli, 20160, Turkey; Vural C., Faculty of Science, Department of Biology, Molecular Biology Section, Pamukkale University, Denizli, 20160, Turkey","Nanozymes are a class of nanomaterials that are capable of mimicking the activities of natural enzymes. They are currently receiving considerable attention due to their advantageous properties. The objective of this study is to provide a comprehensive analysis of the advancements and trends in nanozymes for microbial theranostics research over the past decade through a detailed bibliometric approach. For this purpose, an effective search query was formulated, and relevant publications from 2013 to 2023 were collected from the Web of Science Core Collection database. Subsequently, the following softwares were employed for analysis: VOSviewer, the Bibliometrix R package, and GraphPad Prism 8.0.2. The findings revealed a statistically significant positive correlation (r = 0.993; p < 0.0001) between publications and citations, in addition to an important growth rate of scientific output of approximately 28.90%. China, India, and the USA were the most productive countries, whereas progress in low- and middle-income countries remained constrained. The Chinese Academy of Sciences was the most productive institution, and remarkably almost the top 10 productive authors were from China. Regarding keywords analysis, current research hotspots are primarily concentrated on the application of nanozymes in anti-biofilm-related research, antibacterial activity and therapy, the development of biosensors for microbial detection and control, and the advancement of wound disinfection and therapy. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.","Bibliometric; Diagnostic; Microorganisms; Nanozymes; Science mapping; Therapy","Bibliometrics; Humans; Nanostructures; Theranostic Nanomedicine; Bibliographies; Microorganisms; Theranostics; enzyme; nanoparticle; nanozyme; unclassified drug; nanomaterial; Bibliometric; Bibliometrics analysis; Diagnostic; Microbials; Nanozyme; Natural enzyme; Network visualization; Science mapping; Theranostics; Therapy; antibacterial activity; antibiofilm activity; Article; bibliometrics; China; disinfection; Embase; human; India; low income country; Medline; microorganism detection; middle income country; nonhuman; publication; theranostic nanomedicine; United States; Web of Science; wound care; chemistry; Nanopores","","","","","","","Chen K., Arnold F.H., Engineering new catalytic activities in enzymes, Nature Catalysis, 3, 3, pp. 203-213, (2020); Wu J., Wang X., Wang Q., Lou Z., Li S., Zhu Y., Wei H., Nanomaterials with enzyme-like characteristics (nanozymes): Next-generation artificial enzymes (II), Chemical Society Reviews, 48, 4, pp. 1004-1076, (2019); Bilal M., Khaliq N., Ashraf M., Hussain N., Baqar Z., Zdarta J., Iqbal H.M.N., Enzyme mimic nanomaterials as nanozymes with catalytic attributes, Colloids and Surfaces B: Biointerfaces, 221, (2023); Garcia-Viloca M., Gao J., Karplus M., Truhlar D.G., How enzymes work: Analysis by modern rate theory and computer simulations, Science, 303, 5655, pp. 186-195, (2004); Liu J., Zhang X., Zhang Y., Zhao B., Liu Z., Dong X., Du Y., Mn-based Prussian blue analogues: Multifunctional nanozymes for hydrogen peroxide detection and photothermal therapy of tumors, Talanta, 277, (2024); Ye X., Zhang X., Wang C., Xu R., Li Y., Wei W., Liu S., The enhanced oxidase-like activity of modified nanoceria/ZIF-67 for fluorescence and smartphone-assisted visual detection of tannic acid, Sensors and Actuators B: Chemical, 418, (2024); Perwez M., Lau S.Y., Hussain D., Anboo S., Arshad M., Thakur P., Nanozymes and nanoflower: Physiochemical properties, mechanism and biomedical applications, Colloids and Surfaces B: Biointerfaces, 225, December 2022, (2023); Manea F., Houillon F.B., Pasquato L., Scrimin P., Nanozymes: Gold-nanoparticle-based transphosphorylation catalysts, Angewandte Chemie, 116, 45, pp. 6291-6295, (2004); Gao L., Zhuang J., Nie L., Zhang J., Zhang Y., Gu N., Yan X., Intrinsic peroxidase-like activity of ferromagnetic nanoparticles, Nature Nanotechnology, 2, 9, pp. 577-583, (2007); Zhang R., Yan X., Fan K., Nanozymes inspired by natural enzymes, Accounts of Materials Research, 2, 7, pp. 534-547, (2021); Hong C., Meng X., He J., Fan K., Yan X., Particuology nanozyme : A promising tool from clinical diagnosis and environmental monitoring to wastewater treatment, Particuology, 71, pp. 90-107, (2022); Cheng C., Wang H., Zhao J., Wang Y., Zhao G., Zhang Y., Wang Y., Colloids and Surfaces B : Biointerfaces advances in the application of metal oxide nanozymes in tumor detection and treatment, Colloids and Surfaces B: Biointerfaces, 235, (2024); Saini N., Choudary R., Sethi D., Dhandeep C., Nirmal S., Nanozymes: Classification, synthesis and challenges, Applied Nanoscience, 13, 9, pp. 6433-6443, (2023); Wu Y., Tian X., Jiang Y., Ma H., Wang W., Zhang W., Niu L., Trends in analytical chemistry advances in bimetallic materials and bimetallic oxide nanozymes : Synthesis, classification, catalytic mechanism and application in analytical chemistry, Trends in Analytical Chemistry, 176, (2024); Wu H., Kailasa S.K., Recent advances in nanomaterials-based optical sensors for detection of various biomarkers (inorganic species, organic and biomolecules), Luminescence, 38, 7, pp. 954-998, (2023); Cui M., Xu B., Wang L., Recent advances in multi-metallic-based nanozymes for enhanced catalytic cancer therapy, BMEMat, 2, 1, (2024); Yu X., Wang Y., Zhang J., Liu J., Wang A., Ding L., Recent development of copper-based nanozymes for biomedical applications, Advanced Healthcare Materials, 13, 1, (2024); Gao B., Ye Q., Ding Y., Wu Y., Zhao X., Deng M., Wu Q., Metal-based nanomaterials with enzyme-like characteristics for bacterial rapid detection and control, Coordination Chemistry Reviews, 510, (2024); Sen A., Oswalia J., Yadav S., Vachher M., Nigam A., Recent trends in nanozyme research and their potential therapeutic applications, Current Research in Biotechnology, 7, March, (2024); Mahmudunnabi R.G., Farhana F.Z., Kashaninejad N., Firoz S.H., Shim Y.B., Shiddiky M.J.A., Nanozyme-based electrochemical biosensors for disease biomarker detection, The Analyst, 145, 13, pp. 4398-4420, (2020); Wang W., Gunasekaran S., Nanozymes-based biosensors for food quality and safety, Trends in Analytical Chemistry, 126, (2020); Mathur P., Kumawat M., Nagar R., Singh R., Kumar H., Tailoring metal oxide nanozymes for biomedical applications: Trends, limitations, and perceptions, Analytical and Bioanalytical Chemistry, pp. 1-20, (2024); 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Vural; Faculty of Science, Department of Biology, Molecular Biology Section, Pamukkale University, Denizli, 20160, Turkey; email: canervural@gmail.com","","Springer","","","","","","02732289","","","39625609","English","Appl. Biochem. Biotechnol.","Article","Final","","Scopus","2-s2.0-85211463598" -"Hasibuan H.Y.; Ruhiat Y.; Santosa C.A.H.F.","Hasibuan, Heni Yunilda (59972906800); Ruhiat, Yayat (57190942330); Santosa, Cecep Anwar Hadi Firdos (59676378500)","59972906800; 57190942330; 59676378500","From Cognition to Emotion: Recent Global Research Directions in Mathematical Proficiency","2025","International Journal of Learning, Teaching and Educational Research","24","6","","89","117","28","0","10.26803/ijlter.24.6.5","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105009615387&doi=10.26803%2fijlter.24.6.5&partnerID=40&md5=4954ad7088858ac0ec83de532297fed6","Universitas Sultan Ageng Tirtayasa, Banten, Indonesia","Hasibuan H.Y., Universitas Sultan Ageng Tirtayasa, Banten, Indonesia; Ruhiat Y., Universitas Sultan Ageng Tirtayasa, Banten, Indonesia; Santosa C.A.H.F., Universitas Sultan Ageng Tirtayasa, Banten, Indonesia","Research on mathematical proficiency has gained increasing global attention due to its significance in education and psychology. This study presents a bibliometric analysis of 1,884 articles published between 2020 and 2024 to identify research trends, key contributors, thematic clusters, and global collaboration networks in the field. Utilising VOSviewer and Bibliometrix, two widely used tools for science mapping and visualisation, the analysis reveals 10 thematic clusters, with mathematics, mathematics achievement, academic achievement, and math anxiety emerging as central topics. Among these, mathematics achievement appears as one of the most frequently used keywords, underscoring a strong focus on the relationship between mathematical proficiency and academic outcomes. The United States leads global contributions, supported by prolific institutions and interdisciplinary work published in high-impact journals such as the Journal of Educational Psychology. The analysis also shows a rising number of collaborations across countries and institutions. The findings highlight a growing emphasis on cognitive and socio-emotional factors, including executive functions, working memory and growth mindset. These insights provide a comprehensive roadmap for researchers and policymakers to guide future inquiry, foster interdisciplinary collaboration and develop holistic strategies to improve mathematical proficiency at scale. Limitations include the exclusive use of Scopus-indexed and English-language articles, as well as reliance on keyword-based retrieval. Future studies might incorporate multiple databases, explore culturally contextualised trends, or examine underexplored themes such as pedagogical content knowledge and digital learning environments. © Authors.","bibliometric analysis; mathematical proficiency; mathematics achievement; mathematics education; Scopus database","","","","","","","","Abin A., Nunez J. 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E., Exploring effects of an early math intervention: The importance of parent–child interaction, Child Development, 94, 2, pp. 395-410, (2023); Saefudin A. A., Wijaya A., Dwiningrum S. I. A., Yoga D., The characteristics of the mathematical mindset of junior high school students, Eurasia Journal of Mathematics, Science and Technology Education, 19, 1, pp. 1-13, (2023); Schotten M., Aisati M., Meester W. J. N., Steiginga S., Ross C. A., A brief history of Scopus: The world’s largest abstract and citation database of scientific literature, Research analytics: Boosting university productivity and competitiveness through scientometrics, pp. 31-58, (2017); Sharma G. S., Chintalapati N., Verma P., A bibliometric analysis of social media use for personal learning outcomes using Biblioshiny & VOSviewer, International Journal of System Assurance Engineering and Management, (2024); Spiegel J. A., Goodrich J. M., Morris B. M., Osborne C. M., Lonigan C. J., Relations between executive functions and academic outcomes in elementary school children: A meta-analysis, Psychological Bulletin, 147, 4, pp. 329-351, (2021); Starling-Alves I., Russell-Lasalandra L. L., Lau N. T. T., Moreira Paiva G., Geraldi Haase V., Wilkey E. D., Number and domain both affect the relation between executive function and mathematics achievement: A study of children’s executive function with and without numbers, Developmental Psychology, 60, 12, pp. 2345-2366, (2024); Szczygiel M., More evidence that math anxiety is specific to math in young children: The correlates of the math anxiety questionnaire for children (MAQC), International Electronic Journal of Elementary Education, 12, 5, pp. 429-438, (2020); Szczygiel M., When does math anxiety in parents and teachers predict math anxiety and math achievement in elementary school children? The role of gender and grade year, Social Psychology of Education, 23, 4, pp. 1023-1054, (2020); Szczygiel M., Sari M. 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J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, pp. 523-538, (2010); Vanbecelaere S., Van den Berghe K., Cornillie F., Sasanguie D., Reynvoet B., Depaepe F., The effects of two digital educational games on cognitive and non-cognitive math and reading outcomes, Computers and Education, 143, (2020); Veraksa A. N., Aslanova M. S., Bukhalenkova D. A., Veraksa N. E., Liutsko L., Assessing the effectiveness of differentiated instructional approaches for teaching math to preschoolers with different levels of executive functions, Education Sciences, 10, 7, pp. 1-16, (2020); Visser M., van Eck N. J., Waltman L., Large-scale comparison of bibliographic data sources: Scopus, Web of Science, Dimensions, Crossref, and Microsoft Academic, Quantitative Science Studies, 2, 1, pp. 20-41, (2021); Wen Q.-J., Ren Z.-J., Lu H., Wu J.-F., The progress and trend of BIM research: A bibliometrics-based visualization analysis, Automation in Construction, 124, (2021); Xu X., Zhang Q., Sun J., Wei Y., A bibliometric review on latent topics and research trends in the growth mindset literature for mathematics education, Frontiers in Psychology, 13, (2022); Zhang Y., Yang X., Sun X., Kaiser G., The reciprocal relationship among Chinese senior secondary students’ intrinsic and extrinsic motivation and cognitive engagement in learning mathematics: A three-wave longitudinal study, ZDM-Mathematics Education, 55, 2, pp. 399-412, (2023); Zhong Z., Xu Y., Jin R., Ye C., Zhang M., Zhang H., Executive functions and mathematical competence in Chinese preschool children: A meta-analysis and review, Frontiers in Psychology, 13, (2022); Zivkovic M., Pellizzoni S., Mammarella I. C., Passolunghi M. C., The relationship betweens math anxiety and arithmetic reasoning: The mediating role of working memory and self-competence, Current Psychology, 42, 17, pp. 14506-14516, (2023)","C.A.H.F. Santosa; Universitas Sultan Ageng Tirtayasa, Banten, Indonesia; email: cecepanwar@untirta.ac.id","","Society for Research and Knowledge Management","","","","","","16942116","","","","English","Intl. J. Learn. Teach. Edu. Res.","Article","Final","","Scopus","2-s2.0-105009615387" -"Yang S.; Lai I.K.W.; Wu X.","Yang, Shiqiu (59923802600); Lai, Ivan Ka Wai (26655755300); Wu, Xiaohong (57210184257)","59923802600; 26655755300; 57210184257","A systematic literature review of film tourism research (2004–2023)","2025","Asia Pacific Journal of Tourism Research","","","","","","","0","10.1080/10941665.2025.2511783","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105007011523&doi=10.1080%2f10941665.2025.2511783&partnerID=40&md5=4280ac9c126409875c9db8840c63b799","Faculty of International Tourism and Management, City University of Macau, Taipa, Macao; Centre for Gaming and Tourism Studies, Macao Polytechnic University, Taipa, Macao","Yang S., Faculty of International Tourism and Management, City University of Macau, Taipa, Macao; Lai I.K.W., Centre for Gaming and Tourism Studies, Macao Polytechnic University, Taipa, Macao; Wu X., Faculty of International Tourism and Management, City University of Macau, Taipa, Macao","This study systematically reviews film tourism literature, conducting a bibliometric analysis of 186 articles across 60 journals from 2004 to 2023 obtained from Scopus using the VOSviewer software and Bibliometrix R-package. It investigates the development of film tourism, identifies five research categories (tourist destination, tourists’ film experience, celebrity, film content, and impact of film tourism) by science mapping and content analysis, and proposes five future research directions. It contributes to film tourism research by providing researchers with a solid foundation of film research development and a roadmap for further film tourism research. Recommendations on film production and celebrities are provided. © 2025 Asia Pacific Tourism Association.","bibliometric analysis; Bibliometrix; Film tourism; systematic literature review; VOSviewer","","","","","","","","Aguilar-Rivero M., Moral-Cuadra S., Lopez-Guzman T., Solano-Sanchez M.A., Authenticity and motivations towards film destination, Asia Pacific Journal of Tourism Research, 28, 5, pp. 401-415, (2023); Andersen N., Mapping the expatriate literature: A bibliometric review of the field from 1998 to 2017 and identification of current research fronts, The International Journal of Human Resource Management, 32, 22, pp. 4687-4724, (2021); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Balli F., Balli H.O., Cebeci K., Impacts of exported Turkish soap operas and visa-free entry on inbound tourism to Turkey, Tourism Management, 37, pp. 186-192, (2013); Basarangi I., Um estudo de meta-síntese sobre o efeito de filmes e séries televisivas no marketing de destinação, Revista Rosa dos Ventos - Turismo e Hospitalidade, 14, 4, pp. 1225-1247, (2022); Beeton S., Film-induced tourism, (2005); Beeton S., Understanding film-induced tourism, Tourism Analysis, 11, 3, pp. 181-188, (2006); Beeton S., The advance of film tourism, Tourism and Hospitality Planning & Development, 7, 1, pp. 1-6, (2010); Bretas V.P., Alon I., Franchising research on emerging markets: Bibliometric and content analyses, Journal of Business Research, 133, pp. 51-65, (2021); Brooks S.K., Fanatics: Systematic literature review of factors associated with celebrity worship, and suggested directions for future research, Current Psychology, 40, 2, pp. 864-886, (2021); Buchmann A., Planning and development in film tourism: Insights into the experience of Lord of the Rings film guides, Tourism and Hospitality Planning & Development, 7, 1, pp. 77-84, (2010); Buchmann A., Moore K., Fisher D., Experiencing film tourism: Authenticity & fellowship, Annals of Tourism Research, 37, 1, pp. 229-248, (2010); Calderon-Fajardo V., Future trends in Red Tourism and communist heritage tourism, Asia Pacific Journal of Tourism Research, 28, 10, pp. 1185-1198, (2023); Cardoso L., Estevao C., Fernandes C., Alves H., Film-induced tourism: A systematic literature review, Tourism & Management Studies, 13, 3, pp. 23-30, (2017); Carl D., Kindon S., Smith K., Tourists’ experiences of film locations: New Zealand as ‘Middle-Earth’, Tourism Geographies, 9, 1, pp. 49-63, (2007); Chavan P., Vhatkar A., Shoukat M.H., Mehta M., Ahmad M.S., Tourist tales uncovered: Navigating satisfaction through psychographics and destination impressions–a systematic literature review, Asia Pacific Journal of Tourism Research, 30, 1, pp. 127-145, (2024); Chen C.Y., Influence of celebrity involvement on place attachment: Role of destination image in film tourism, Asia Pacific Journal of Tourism Research, 23, 1, pp. 1-14, (2017); Chen J., Wu X., Lai I.K.W., A systematic literature review of virtual technology in hospitality and tourism (2013–2022), Sage Open, 13, 3, (2023); Chen Q.P., Wu J.J., Ruan W.Q., What fascinates you? Structural dimension and element analysis of sensory impressions of tourist destinations created by animated works, Asia Pacific Journal of Tourism Research, 26, 9, pp. 1038-1054, (2021); Ciki K., Inan R., Bulsu C., Research trends in film tourism: A bibliometric analysis using the WoS database, Prace i study geograficzne, 68, 1, pp. 83-98, (2023); Connell J., Toddlers, tourism and Tobermory: Destination marketing issues and television-induced tourism, Tourism Management, 26, 5, pp. 763-776, (2005); Connell J., Film tourism–evolution, progress and prospects, Tourism Management, 33, 5, pp. 1007-1029, (2012); Connell J., Meyer D., Balamory revisited: An evaluation of the screen tourism destination-tourist nexus, Tourism Management, 30, 2, pp. 194-207, (2009); Creswell J.W., Creswell J.D., Research design: Qualitative, quantitative, and mixed methods approaches, (2017); Croy W.G., Planning for film tourism: Active destination image management, Tourism and Hospitality Planning & Development, 7, 1, pp. 21-30, (2010); Croy W.G., Film tourism: Sustained economic contributions to destinations, Worldwide Hospitality and Tourism Themes, 3, 2, pp. 159-164, (2011); Da Fonseca J.L., Gomes C.L., Film-Induced tourism in Latin American context: A systematic literature review, Revista Rosa dos Ventos - Turismo e Hospitalidade, 12, 3, pp. 657-682, (2020); Dominguez-Azcue J., Almeida-Garcia F., Perez-Tapia G., Cestino-Gonzalez E., Films and destinations—towards a film destination: A review, Information, 12, 1, (2021); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Du Y., Li J., Pan B., Zhang Y., Lost in Thailand: A case study on the impact of a film on tourist behavior, Journal of Vacation Marketing, 26, 3, pp. 365-377, (2020); Frolova E., Zielinski S., Kiatkawsin K., Do historical TV series boost intention to visit a country and its cultural sites? The case of historical Korean dramas, Asia Pacific Journal of Tourism Research, 30, 5, pp. 594-608, (2025); Fu H., Ye B.H., Xiang J., Reality TV, audience travel intentions, and destination image, Tourism Management, 55, pp. 37-48, (2016); Giles D.C., How do fan and celebrity identities become established on Twitter? A study of ‘social media natives’ and their followers, Celebrity Studies, 8, 3, pp. 445-460, (2017); Hahm J., Wang Y., Film-induced tourism as a vehicle for destination marketing: Is it worth the efforts?, Journal of Travel & Tourism Marketing, 28, 2, pp. 165-179, (2011); Hao X., Ryan C., Interpretation, film language and tourist destinations: A case study of Hibiscus Town, China, Annals of Tourism Research, 42, pp. 334-358, (2013); Hudson S., Ritchie J.B., Promoting destinations via film tourism: An empirical identification of supporting marketing initiatives, Journal of Travel Research, 44, 4, pp. 387-396, (2006); Hudson S., Ritchie J.B., Film tourism and destination marketing: The case of Captain Corelli’s Mandolin, Journal of Vacation Marketing, 12, 3, pp. 256-268, (2006); Hudson S., Wang Y., Gil S.M., The influence of a film on destination image and the desire to travel: A cross-cultural comparison, International Journal of Tourism Research, 13, 2, pp. 177-190, (2011); Kim S., Extraordinary experience: Re-enacting and photographing at screen tourism locations, Tourism and Hospitality Planning & Development, 7, 1, pp. 59-75, (2010); Kim S., Audience involvement and film tourism experiences: Emotional places, emotional experiences, Tourism Management, 33, 2, pp. 387-396, (2012); Kim S., A cross-cultural study of on-site film-tourism experiences among Chinese, Japanese, Taiwanese and Thai visitors to the Daejanggeum Theme Park, South Korea, Current Issues in Tourism, 15, 8, pp. 759-776, (2012); Kim S., The relationships of on-site film-tourism experiences, satisfaction, and behavioral intentions: The case of Asian audience’s responses to a Korean historical TV drama, Journal of Travel & Tourism Marketing, 29, 5, pp. 472-484, (2012); Kim S., The impact of TV drama attributes on touristic experiences at film tourism destinations, Tourism Analysis, 17, 5, pp. 573-585, (2012); Kim S.S., Agrusa J., Lee H., Chon K., Effects of Korean television dramas on the flow of Japanese tourists, Tourism Management, 28, 5, pp. 1340-1353, (2007); Kim S., Assaker G., An empirical examination of the antecedents of film tourism experience: A structural model approach, Journal of Travel & Tourism Marketing, 31, 2, pp. 251-268, (2014); Kim J.H., Badu-Baiden F., Kim S., Koseoglu M.A., Baah N.G., Evolution of the memorable tourism experience and future research prospects, Journal of Travel Research, 63, 6, pp. 1315-1334, (2024); Kim S., Kim S., Perceived values of TV drama, audience involvement, and behavioral intention in film tourism, Journal of Travel & Tourism Marketing, 35, 3, pp. 259-272, (2017); Kim S., Kim S., Segmentation of potential film tourists by film nostalgia and preferred film tourism program, Journal of Travel & Tourism Marketing, 35, 3, pp. 285-305, (2017); Kim S., Kim S., Han H., Effects of TV drama celebrities on national image and behavioral intention, Asia Pacific Journal of Tourism Research, 24, 3, pp. 233-249, (2018); Kim S., Kim S., Heo C., Assessment of TV drama/film production towns as a rural tourism growth engine, Asia Pacific Journal of Tourism Research, 20, 7, pp. 730-760, (2014); Kim S., Kim S., King B., Nostalgia film tourism and its potential for destination development, Journal of Travel & Tourism Marketing, 36, 2, pp. 236-252, (2019); Kim S., Kim S., Petrick J.F., The effect of film nostalgia on involvement, familiarity, and behavioral intentions, Journal of Travel Research, 58, 2, pp. 283-297, (2019); Kim S.S., Lee H., Chon K.S., Segmentation of different types of Hallyu tourists using a multinomial model and its marketing implications, Journal of Hospitality & Tourism Research, 34, 3, pp. 341-363, (2010); Kim S., Long P., Touring TV soap operas: Genre in film tourism research, Tourist Studies, 12, 2, pp. 173-185, (2012); Kim S., Nam C., Hallyu revisited: Challenges and opportunities for the South Korean tourism, Asia Pacific Journal of Tourism Research, 21, 5, pp. 524-540, (2015); Korossy N., dos Santos Paes R.G., Cordeiro I.J.D., Estado da arte sobre turismo e cinema no Brasil: uma revisão integrativa da literatura, Podium Sport Leisure and Tourism Review, 10, 1, pp. 109-140, (2021); Krittayaruangroj K., Suriyankietkaew S., Hallinger P., Research on sustainability in community-based tourism: A bibliometric review and future directions, Asia Pacific Journal of Tourism Research, 28, 9, pp. 1031-1051, (2023); Kumar A., Basu R., Kumar S., Ali F., Dark tourism research: A bibliometric analysis and future research directions, Asia Pacific Journal of Tourism Research, 29, 8, pp. 901-921, (2024); Li S., Li H., Song H., Lundberg C., Shen S., The economic impact of on-screen tourism: The case of The Lord of the Rings and the Hobbit, Tourism Management, 60, pp. 177-187, (2017); Li S., Tian W., Lundberg C., Gkritzali A., Sundstrom M., Two tales of one city: Fantasy proneness, authenticity, and loyalty of on-screen tourism destinations, Journal of Travel Research, 60, 8, pp. 1802-1820, (2021); Liu S., Gao J., Zhang G., Cheng L., Zhang R., How to speak destinations more efficiently: A study on the effects of narration in tourism films on viewer perceptions and intentions, Asia Pacific Journal of Tourism Research, 29, 12, pp. 1509-1528, (2024); Liu T., Liu S., Rahman I., International anime tourists’ experiences: A netnography of popular Japanese anime tourism destinations, Asia Pacific Journal of Tourism Research, 27, 2, pp. 135-156, (2022); Lundberg C., Ziakas V., Morgan N., Conceptualising on-screen tourism destination development, Tourist Studies, 18, 1, pp. 83-104, (2018); Luong T.B., Celebrity involvement, film destination image, place attachment, behavioral intention: The moderating role of e-word of mouth utilitarian function, Asia Pacific Journal of Tourism Research, 28, 9, pp. 949-964, (2023); Martyn J., Bibliographic coupling, Journal of Documentation, 20, 4, (1964); Milazzo L., Santos C.A., Fanship and imagination: The transformation of everyday spaces into Lieux D’Imagination, Annals of Tourism Research, 94, (2022); Moher D., Liberati A., Tetzlaff J., Altman D.G., Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement, Annals of Internal Medicine, 151, 4, pp. 264-269, (2009); Mongeon P., Paul-Hus A., The journal coverage of web of Science and Scopus: A comparative analysis, Scientometrics, 106, 1, pp. 213-228, (2016); Moritz P., Hrivnak M., Mazuchova L., Sandorova Z., Who takes part in film tourism? The analysis of determinants of visiting film locations, International Journal of Tourism Research, 26, 1, (2024); Nakayama C., Film-induced tourism studies on Asia: A systematic literature review, Tourism Review International, 25, 1, pp. 63-78, (2021); O'Connor N., Kim S., Pictures and prose: Exploring the impact of literary and film tourism, Journal of Tourism and Cultural Change, 12, 1, pp. 1-17, (2014); Oh J.E., Kim K.J., How nostalgic animations bring tourists to theme parks: The case of Hayao Miyazaki’s works, Journal of Hospitality and Tourism Management, 45, pp. 464-469, (2020); Ozkose H., Uyar Oguz H., Aslan A., Scientific mapping of smart tourism: A content analysis study, Asia Pacific Journal of Tourism Research, 28, 9, pp. 923-948, (2023); Paul J., Criado A.R., The art of writing literature review: What do we know and what do we need to know?, International Business Review, 29, 4, (2020); Pavesi A., Denizci Guillet B., Law R., Collage creation: Unexplored potential in tourism research, Journal of Travel & Tourism Marketing, 34, 5, pp. 571-589, (2017); Qiu X., Kong H., Wang K., Zhang N., Park S., Bu N., Past, present, and future of tourism and climate change research: Bibliometric analysis based on VOSviewer and SciMAT, Asia Pacific Journal of Tourism Research, 28, 1, pp. 36-55, (2023); Rajaguru R., Motion picture-induced visual, vocal and celebrity effects on tourism motivation: Stimulus organism response model, Asia Pacific Journal of Tourism Research, 19, 4, pp. 375-388, (2013); Rajasekaram K., Hewege C.R., Perera C.R., “Tourists’ experience” in dark tourism: A systematic literature review and future research directions, Asia Pacific Journal of Tourism Research, 27, 2, pp. 206-224, (2022); Rittichainuwat B., Rattanaphinanchai S., Applying a mixed method of quantitative and qualitative design in explaining the travel motivation of film tourists in visiting a film-shooting destination, Tourism Management, 46, pp. 136-147, (2015); Rogers E.M., Diffusion of innovations, (1995); Schiavone R., Brandellero A., (M)apping film in Scotland: Film tour maps, apps and ‘real’ engagements with virtual place, Tourist Studies, 24, 1, pp. 7-33, (2024); Shen H., Lai I.K.W., Souvenirs: A systematic literature review (1981–2020) and research agenda, Sage Open, 12, 2, (2022); St-James Y., Darveau J., Fortin J., Immersion in film tourist experiences, Journal of Travel & Tourism Marketing, 35, 3, pp. 273-284, (2017); (2024); Swain S., Jebarajakirthy C., Sharma B.K., Maseeh H.I., Agrawal A., Shah J., Saha R., Place branding: A systematic literature review and future research agenda, Journal of Travel Research, 63, 3, pp. 535-564, (2024); Teng H.Y., Chen C.Y., Enhancing celebrity fan-destination relationship in film-induced tourism: The effect of authenticity, Tourism Management Perspectives, 33, (2020); Thelen T., Kim S., Scherer E., Film tourism impacts: A multi-stakeholder longitudinal approach, Tourism Recreation Research, 45, 3, pp. 291-306, (2020); Truong D., Xiaoming Liu R., Yu J., Mixed methods research in tourism and hospitality journals, International Journal of Contemporary Hospitality Management, 32, 4, pp. 1563-1579, (2020); Tung V.W.S., Lee S., Hudson S., The potential of anime for destination marketing: Fantasies, otaku, and the kidult segment, Current Issues in Tourism, 22, 12, pp. 1423-1436, (2019); Vila N.A., Brea J.A.F., de Carlos P., Film tourism in Spain: Destination awareness and visit motivation as determinants to visit places seen in TV series, European Research on Management and Business Economics, 27, 1, (2021); Wen H., Josiam B.M., Spears D.L., Yang Y., Influence of movies and television on Chinese tourists perception toward international tourism destinations, Tourism Management Perspectives, 28, pp. 211-219, (2018); Wright D.W.M., Jarratt D., Halford E., The twilight effect, post-film tourism and diversification: The future of Forks, WA, Journal of Tourism Futures, 9, 2, pp. 196-213, (2023); Wu X., Lai I.K.W., The acceptance of augmented reality tour app for promoting film-induced tourism: The effect of celebrity involvement and personal innovativeness, Journal of Hospitality and Tourism Technology, 12, 3, pp. 454-470, (2021); Wu X., Lai I.K.W., How to promote film tourism more effectively? From a perspective of self-congruity and film tourism experience, Asia Pacific Journal of Tourism Research, 28, 6, pp. 556-572, (2023); Wu X., Lai I.K.W., How destination personality dimensions influence film tourists’ destination loyalty: An application of self-congruity theory, Current Issues in Tourism, 26, 21, pp. 3547-3562, (2023); Wu X., Lai I.K.W., How do cartoon destination pictures inspire cartoon-induced tourism? Based on the associative network model and dual-coding theory, Journal of Destination Marketing & Management, 36, (2025); Wu P., Zou Y., Jin D., Li Y., Zhang J., Daily vlog-induced tourism: Impact of enduring involvement on travel intention, Tourism Review, 79, 5, pp. 1166-1181, (2024); Yen C.H., Croy W.G., Film tourism: Celebrity involvement, celebrity worship and destination image, Current Issues in Tourism, 19, 10, pp. 1027-1044, (2016); Yen C.H., Teng H.Y., Celebrity involvement, perceived value, and behavioral intentions in popular media-induced tourism, Journal of Hospitality & Tourism Research, 39, 2, pp. 225-244, (2015); Yoon Y., Kim S.S., Kim S.S., Successful and unsuccessful film tourism destinations: From the perspective of Korean local residents’ perceptions of film tourism impacts, Tourism Analysis, 20, 3, pp. 297-311, (2015); Zhang X., Ryan C., Cave J., Residents, their use of a tourist facility and contribution to tourist ambience: Narratives from a film tourism site in Beijing, Tourism Management, 52, pp. 416-429, (2016); Zhao M., Li X., Wang H., Wu W., Law R., Asia Pacific Journal of Tourism Research: A bibliometric analysis from 1996 to 2023, Asia Pacific Journal of Tourism Research, 29, 11, pp. 1382-1399, (2024); Zheng D., Huang C., Oraltay B., Digital cultural tourism: Progress and a proposed framework for future research, Asia Pacific Journal of Tourism Research, 28, 3, pp. 234-253, (2023); Zou T., Xi X., Hu X., Mapping the evolution and future directions of creative tourism: A comprehensive bibliometric analysis, Asia Pacific Journal of Tourism Research, 30, 1, pp. 72-91, (2024)","X. Wu; Faculty of International Tourism and Management, City University of Macau, Taipa, Macao; email: xhwu@cityu.edu.mo","","Routledge","","","","","","10941665","","","","English","Asia Pac. J. Tour. Res.","Article","Article in press","","Scopus","2-s2.0-105007011523" -"Vrdoljak L.; Racetin I.; Zrinjski M.","Vrdoljak, Ljerka (57222657819); Racetin, Ivana (14036067200); Zrinjski, Mladen (23476298900)","57222657819; 14036067200; 23476298900","Bibliometric Analysis of Remote Sensing over Marine Areas for Sustainable Development: Global Trends and Worldwide Collaboration","2024","Sustainability (Switzerland)","16","14","6211","","","","2","10.3390/su16146211","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199613495&doi=10.3390%2fsu16146211&partnerID=40&md5=69515c4b12fcd5322ce6a616238538f9","Hydrographic Institute of the Republic of Croatia, Split, 21000, Croatia; Faculty of Civil Engineering, Architecture and Geodesy, University of Split, Split, 21000, Croatia; Faculty of Geodesy, University of Zagreb, Zagreb, 10000, Croatia","Vrdoljak L., Hydrographic Institute of the Republic of Croatia, Split, 21000, Croatia; Racetin I., Faculty of Civil Engineering, Architecture and Geodesy, University of Split, Split, 21000, Croatia; Zrinjski M., Faculty of Geodesy, University of Zagreb, Zagreb, 10000, Croatia","More than two-thirds of the Earth’s surface is covered by oceans and yet only a small portion of these oceans has been directly explored in detail, highlighting the need for powerful tools like remote sensing (RS) technology to bridge this gap. International frameworks, the 2030 Agenda for Sustainable Development, and Ocean Decade point out the significance of marine areas for achieving sustainable growth. This study conducts a bibliometric analysis of RS over marine areas for sustainable development to identify key contributors, collaboration networks, and evolving research themes from the beginning of the 21st century until last year. Using the Web of Science Core Collection database, 499 relevant articles published between 2000 and 2023 were identified. The bibliometric analysis showed a significant increase in scientific productivity related to the field. On an international level, China emerges as the most productive country, but international collaboration has played a crucial role, with 36.87% of articles resulting from international co-authorship, pointing to the global nature of research in this field. RS technology has continuously evolved from airborne sensors to the augmentation of Earth Observation missions. Our findings reveal a shift towards automated analysis and processing of RS data using machine learning techniques to integrate large datasets and develop robust scientific solutions. © 2024 by the authors.","Bibliometrix; blue growth; Earth Observation; science mapping","China; bibliography; mapping; observational method; remote sensing; sensor; Sustainable Development Goal; trend analysis","","","","","European Commission, EC; European Regional Development Fund, ERDF","This research is partially supported through project KK.01.1.1.02.0027, a project co-financed by the Croatian Government and the European Union through the European Regional Development Fund\u2014the Competitiveness and Cohesion Operational Program. ","Wolfl A.-C., Snaith H., Amirebrahimi S., Devey C.W., Dorschel B., Ferrini V., Huvenne V.A.I., Jakobsson M., Jencks J., Johnston G., Et al., Seafloor Mapping—The Challenge of a Truly Global Ocean Bathymetry, Front. Mar. 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Res, 133, pp. 285-296, (2021); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, pp. 523-538, (2010); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr, 11, pp. 959-975, (2017); Zhang H., Huang M., Qing X., Li G., Tian C., Bibliometric Analysis of Global Remote Sensing Research during 2010–2015, ISPRS Int. J. Geo-Inf, 6, (2017); Araya-Lopez R., de Paula Costa M.D., Wartman M., Macreadie P.I., Trends in the application of remote sensing in blue carbon science, Ecol. Evol, 13, (2023); Wang Q., Wang J., Xue M., Zhang X., Characteristics and Trends of Ocean Remote Sensing Research from 1990 to 2020: A Bibliometric Network Analysis and Its Implications, J. Mar. Sci. Eng, 10, (2022); Ekmen O., Kocaman S., Remote sensing for UN SDGs: A global analysis of research and collaborations, Egypt. J. Remote Sens. 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Informetr, 10, pp. 347-364, (2016); Liu C., Li W., Xu J., Zhou H., Li C., Wang W., Global trends and characteristics of ecological security research in the early 21st century: A literature review and bibliometric analysis, Ecol. Indic, 137, (2022); Pohl C., Van Genderen J.L., Review Article Multisensor Image Fusion in Remote Sensing: Concepts, Methods and Applications, Int. J. Remote Sens, 19, pp. 823-854, (1998); Carpenter C.R., Cone D.C., Sarli C.C., Using publication metrics to highlight academic productivity and research impact, Acad. Emerg. Med, 21, pp. 1160-1172, (2014); Kozoderov V.V., A Scientific Approach to Employ Monitoring and Modelling Techniques for Global Change and Terrestrial Ecosystems and Other Related Projects, J. Biogeogr, 22, pp. 927-933, (1995); Carr M.-E., Estimation of potential productivity in Eastern Boundary Currents using remote sensing, Deep Sea Res. Part II Top. Stud. Oceanogr, 49, pp. 59-80, (2001); Petropoulos G.P., Ireland G., Barrett B., Surface soil moisture retrievals from remote sensing: Current status, products & future trends, Phys. Chem. Earth Parts A/B/C, 83–84, pp. 36-56, (2015); Chen B., Xiao X., Li X., Pan L., Doughty R., Ma J., Dong J., Qin Y., Zhao B., Wu Z., Et al., A mangrove forest map of China in 2015: Analysis of time series Landsat 7/8 and Sentinel-1A imagery in Google Earth Engine cloud computing platform, ISPRS J. Photogramm. Remote Sens, 131, pp. 104-120, (2017); McArthur M.A., Brooke B.P., Przeslawski R., Ryan D.A., Lucieer V.L., Nichol S., McCallum A.W., Mellin C., Cresswell I.D., Radke L.C., On the use of abiotic surrogates to describe marine benthic biodiversity, Estuar. Coast. Shelf Sci, 88, pp. 21-32, (2010); Wu J., Zhang Q., Li A., Historical landscape dynamics of Inner Mongolia: Patterns, drivers, and impacts, Landsc. Ecol, 30, pp. 1579-1598, (2015); Appeaning Addo K., Walkden M., Mills J.P., Detection, Measurement and Prediction of Shoreline Recession in Accra, Ghana, ISPRS J. Photogramm. Remote Sens, 63, pp. 543-558, (2008); Aschbacher J., Milagro-Perez M.P., The European Earth Monitoring (GMES) Programme: Status and Perspectives, Remote Sens. Environ, 120, pp. 3-8, (2012); Islam M.A., Mitra D., Dewan A., Akhter S.H., Coastal Multi-Hazard Vulnerability Assessment along the Ganges Deltaic Coast of Bangladesh—A Geospatial Approach, Ocean Coast. Manag, 127, pp. 1-15, (2016); Radiarta I.N., Saitoh S.-I., Miyazono A., GIS-Based Multi-Criteria Evaluation Models for Identifying Suitable Sites for Japanese Scallop (Mizuhopecten yessoensis) Aquaculture in Funka Bay, Southwestern Hokkaido, Japan, Aquaculture, 284, pp. 127-135, (2008); Wabnitz C.C., Andrefouet S., Torres-Pulliza D., Muller-Karger F.E., Kramer P.A., Regional-Scale Seagrass Habitat Mapping in the Wider Caribbean Region Using Landsat Sensors: Applications to Conservation and Ecology, Remote Sens. Environ, 112, pp. 3455-3467, (2008); Cullen J.J., Primary Production Methods, Encyclopedia of Ocean Sciences, pp. 2277-2284, (2001); Pekel J.F., Cottam A., Gorelick N., Belward A.S., High-resolution mapping of global surface water and its long-term changes, Remote Sens, 8, (2016); Wang X., Xiao X., Zou Z., Hou L., Qin Y., Dong J., Doughty R.B., Chen B., Zhang X., Chen Y., Et al., Mapping Coastal Wetlands of China Using Time Series Landsat Images in 2018 and Google Earth Engine, ISPRS J. Photogramm. Remote Sens, 163, pp. 312-326, (2020); Gao B.C., 1996. NDWI—A normalized difference water index for remote sensing of vegetation liquid water from space, Remote Sens. Environ, 58, pp. 257-266, (1996); Tucker C.J., Red and Photographic Infrared Linear Combinations for Monitoring Vegetation, Remote Sens. Environ, 8, pp. 127-150, (1979); Gholizadeh M.H., Melesse A.M., Reddi L., A Comprehensive Review on Water Quality Parameters Estimation Using Remote Sensing Techniques, Sensors, 16, (2016); Morel A., Prieur L., Analysis of variations in ocean color, Limnol. Oceanogr, 22, pp. 709-722, (1977); Huang C., Song K., Kim S., Townshend J.R.G., Davis P., Masek J.G., Goward S.N., Use of a dark object concept and support vector machines to automate forest cover change analysis, Remote Sens. Environ, 112, pp. 970-985, (2008); Gorelick N., Hancher M., Dixon M., Ilyushchenko S., Thau D., Moore R., Google Earth Engine: Planetary-scale geospatial analysis for everyone, Remote Sens. Environ, 202, pp. 18-27, (2017); Mcleod E., Chmura G.L., Bouillon S., Salm R., Bjork M., Duarte C.M., Lovelock C.E., Schlesinger W.H., Silliman B.R., A blueprint for blue carbon: Toward an improved understanding of the role of vegetated coastal habitats in sequestering CO2, Front. Ecol. Environ, 9, pp. 552-560, (2011); Foody G.M., Status of land cover classification accuracy assessment, Remote Sens. Environ, 80, pp. 185-201, (2002); Ivushkin K., Bartholomeus H., Bregt A.K., Pulatov A., Kempen B., De Sousa L., Global mapping of soil salinity change, Remote Sens. Environ, 231, (2019); Brammer H., Bangladesh’s dynamic coastal regions and sea-level rise, Climate Risk Manag, 1, pp. 51-62, (2014); Adger W.N., Vulnerability, Glob. Environ. Change, 16, pp. 268-281, (2006); Gupta K., Mukhopadhyay A., Giri S., Chanda A., Majumdar S.D., Samanta S., Mitra D., Samal R.N., Pattnaik A.K., Hazra S., An index for discrimination of mangroves from non-mangroves using LANDSAT 8 OLI imagery, MethodsX, 5, pp. 1129-1139, (2018); Funk C., Peterson P., Landsfeld M., Pedreros D., Verdin J., Shukla S., Husak G., Rowland J., Harrison L., Hoell A., Et al., The climate hazards infrared precipitation with stations—A new environmental record for monitoring extremes, Sci Data, 2, (2015); McKee K.L., Cahoon D.R., Feller I.C., Caribbean mangroves adjust to rising sea level through biotic controls on change in soil elevation, Glob. Ecol. Biogeogr, 16, pp. 545-556, (2007); Tzachor A., Hendel O., Richards C.E., Digital twins: A stepping stone to achieve ocean sustainability?, NPJ Ocean Sustain, 2, (2023); Racetin I., Ostojic Skomrlj N., Peko M., Zrinjski M., Fuzzy Multi-Criteria Decision for Geoinformation System-Based Offshore Wind Farm Positioning in Croatia, Energies, 16, (2023); Tian Y., Yang Z., Yu X., Jia Z., Rosso M., Dedman S., Zhu J., Xia Y., Zhang G., Yang J., Et al., Can we quantify the aquatic environmental plastic load from aquaculture?, Water Res, 219, (2022)","L. Vrdoljak; Hydrographic Institute of the Republic of Croatia, Split, 21000, Croatia; email: ljerka.vrdoljak@hhi.hr","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20711050","","","","English","Sustainability","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85199613495" -"Boonroungrut C.; Muangkaew K.; Phoyen K.; Vechpong T.; Punyakitphokin W.; Khawda G.; Nantachai G.; Eiamnate N.; Worakul P.; M’manga C.; Saroinsong W.P.","Boonroungrut, Chinun (57205351102); Muangkaew, Kanyarat (57720193200); Phoyen, Kamol (59416303100); Vechpong, Thitima (57226497195); Punyakitphokin, Wananya (59415588100); Khawda, Gunchanon (58772392100); Nantachai, Gallayaporn (57372859500); Eiamnate, Nuttawut (58163160000); Worakul, Puangsoy (59416068300); M’manga, Chilungamo (58071232300); Saroinsong, Wulan Patria (57413608300)","57205351102; 57720193200; 59416303100; 57226497195; 59415588100; 58772392100; 57372859500; 58163160000; 59416068300; 58071232300; 57413608300","Visualising the scientific landscape of global research in self-compassion: A bibliometric analysis","2024","Knowledge Management and E-Learning","16","1","","186","207","21","0","10.34105/j.kmel.2024.16.009","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85209548157&doi=10.34105%2fj.kmel.2024.16.009&partnerID=40&md5=4df3c254624dbb1c517d752261eb5a03","Faculty of Education, Silpakorn University, Thailand; Faculty of Medicine, Chulalongkorn University, Thailand; Somdet Pra Sungharaj Nyanasumvara Geriatric Hospital, Thailand; Faculty of Liberal Arts, Rajamangala University of Technology Suvarnabhumi, Thailand; Faculty of Education, Prince of Songkla University, Thailand; The School of Global and Public Health, Kamuzu University of Health Sciences, Malawi; Faculty of Education, Universitas Negri Surabay, Indonesia","Boonroungrut C., Faculty of Education, Silpakorn University, Thailand; Muangkaew K., Faculty of Education, Silpakorn University, Thailand; Phoyen K., Faculty of Education, Silpakorn University, Thailand; Vechpong T., Faculty of Education, Silpakorn University, Thailand; Punyakitphokin W., Faculty of Education, Silpakorn University, Thailand; Khawda G., Faculty of Education, Silpakorn University, Thailand; Nantachai G., Faculty of Medicine, Chulalongkorn University, Thailand, Somdet Pra Sungharaj Nyanasumvara Geriatric Hospital, Thailand; Eiamnate N., Faculty of Liberal Arts, Rajamangala University of Technology Suvarnabhumi, Thailand; Worakul P., Faculty of Education, Prince of Songkla University, Thailand; M’manga C., The School of Global and Public Health, Kamuzu University of Health Sciences, Malawi; Saroinsong W.P., Faculty of Education, Universitas Negri Surabay, Indonesia","Research in self-compassion has rapidly increased. Providing a comprehension of the scientific knowledge landscape will be helpful for researchers to identify the gaps and develop future research ideas in this field without subjectivity. Thus, overarching structures in self-compassion Scopus-indexed research were sought to be analysed here. Bibliometric techniques were used to extract documents indexed in Scopus under the domain of self-compassion (N = 1,764 articles) using bibliophily, a web interface of the Bibliometrix 3.0 and VOSviewer to conduct analysis and visualisation. The number of published articles shows an upward trend; the United States occupies the leading position in publication volumes and citations. Undoubtedly, K. D. Neff and her sustained cited model were reported as a prolific author and influential article in self-compassion literature. The top affiliation was the University of Texas at Austin, which was the leading university in both production and citation. Mindfulness was a key journal that was considered in publication volume and received citations; however, authors trended to publish from diverse selected sources. The top 50 most frequently used terms were related to individual differences and psychological status. Finally, the thematic mapping provided a comprehensive illustration showing significant themes and knowledge gaps in self-compassion research, which categorised individual differences as basic, measurement validation as niche and PTSD as emerging themes. The current findings presented scientific mappings and extensive tables containing information that usefully proposes future directions and the critical broader scope of research in self-compassion. © 2024 Hong Kong Bao Long Accounting And Secretarial Limited. All rights reserved.","Bibliometric analysis; Science mapping; Self-compassion","","","","","","","","Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Ball R., An introduction to bibliometrics: New development and trends, (2017); Barnard L. K., Curry J. F., Self-compassion: Conceptualizations, correlates, & interventions, Review of General Psychology, 15, 4, pp. 289-303, (2011); Bluth K., Neff K. D., New frontiers in understanding the benefits of self-compassion, Self and Identity, 17, 6, pp. 605-608, (2018); Boonroungrut C., Saroinsong W. P., Thamdee N., Research on students in COVID-19 pandemic outbreaks: A bibliometric network analysis, International Journal of Instruction, 15, 1, pp. 457-472, (2022); Borner K., Chen C., Boyack K. W., Visualizing knowledge domains, Annual Review of Information Science and Technology, 37, 1, pp. 179-255, (2003); Canas A. J., Reiska P., Shvaikovsky O., Improving learning and understanding through concept mapping, Knowledge Management & E-Learning, 15, 3, pp. 369-380, (2023); Cobo M. J., Lopez-Herrera A. G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Crego A., Yela J. R., Riesco-Matias P., Gomez-Martinez M. A., Vicente-Arruebarrena A., The benefits of self-compassion in mental health professionals: A systematic review of empirical research, Psychology Research and Behavior Management, 15, pp. 2599-2620, (2022); Della Corte V., Del Gaudio G., Sepe F., Luongo S., Destination resilience and innovation for advanced sustainable tourism management: A bibliometric analysis, Sustainability, 13, 22, (2021); Dervis H., Bibliometric analysis using Bibliometrix and R Package, Journal of Scientometric Research, 8, 3, pp. 156-160, (2019); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Gilbert P., Introducing compassion-focused therapy, Advances in Psychiatric Treatment, 15, 3, pp. 199-208, (2009); Goldberg S. B., Tucker R. P., Greene P. A., Simpson T. L., Kearney D. J., Davidson R. J., Is mindfulness research methodology improving over time? A systematic review, PloS ONE, 12, 10, (2017); Gu J., Baer R., Cavanagh K., Kuyken W., Strauss C., Development and psychometric properties of the Sussex-Oxford Compassion Scales (SOCS), Assessment, 27, 1, pp. 3-20, (2020); Khawda G., Boonroungrut C., Nantachai G., Eiamnate N., Exploring the clusters in self-compassion research: A bibliometric analysis, Asian Education and Learning Review, 1, 1, pp. 11-18, (2023); Kristin N., Istvan T. K., Marissa K., Ashley K., Oliver D., The development and validation of the state self-compassion scale (long and short form), Mindfulness, 12, 1, pp. 121-140, (2021); Kuhn T. S., The structure of scientific revolutions, (1962); Leary M. R., Tate E. B., Adams C. E., Batts Allen A., Hancock J., Self-compassion and reactions to unpleasant self-relevant events: The implications of treating oneself kindly, Journal of Personality and Social Psychology, 92, 5, pp. 887-904, (2007); Le Thi Thu H., Tran T., Trinh Thi Phuong T., Le Thi Tuyet T., Le Huy H., Vu Thi T., Two decades of STEM education research in middle school: A bibliometrics analysis in Scopus database (2000–2020), Education Sciences, 11, 7, (2021); Luther L., Tiberius V., Brem A., User experience (UX) in business, management, and psychology: A bibliometric mapping of the current state of research, Multimodal Technologies and Interaction, 4, 2, (2020); MacBeth A., Gumley A., Exploring compassion: A meta-analysis of the association between self-compassion and psychopathology, Clinical Psychology Review, 32, 6, pp. 545-552, (2012); Mongeon P., Paul-Hus A., The journal coverage of Web of Science and Scopus: A comparative analysis, Scientometrics, 106, pp. 213-228, (2016); Moral-Munoz J. A., Herrera-Viedma E., Santisteban-Espejo A., Cobo M. J., Software tools for conducting bibliometric analysis in science: An up-to-date review, Profesional de la Información, 29, 1, (2020); Muris P., Otgaar H., The process of science: A critical evaluation of more than 15 years of research on self-compassion with the self-compassion scale, Mindfulness, 11, 6, pp. 1469-1482, (2020); Muris P., Petrocchi N., Protection or vulnerability? A meta‐analysis of the relations between the positive and negative components of self‐compassion and psychopathology, Clinical Psychology & Psychotherapy, 24, 2, pp. 373-383, (2017); Neff K. D., The development and validation of a scale to measure self-compassion, Self and Identity, 2, 3, pp. 223-250, (2003); Neff K. D., Self-compassion: The proven power of being kind to yourself, (2011); Neff K. D., Self-compassion: Theory, method, research, and intervention, Annual Review of Psychology, 74, pp. 193-218, (2023); Neff K. D., Germer C. K., A pilot study and randomized controlled trial of the mindful self‐compassion program, Journal of Clinical Psychology, 69, 1, pp. 28-44, (2013); Neff K. D., Kirkpatrick K. L., Rude S. S., Self-compassion and adaptive psychological functioning, Journal of Research in Personality, 41, 1, pp. 139-154, (2007); Saroinsong W. P., Boonroungrut C., Sidiq B. A., Meylinda C. A., Fauziyah D. L., Wulandari L., Cultivating the value of empathy in the family develops a self-compassion attitude in children, Proceedings of the International Joint Conference on Arts and Humanities 2021 (IJCAH 2021), pp. 1287-1293, (2021); Perianes-Rodriguez A., Waltman L., Van Eck N. J., Constructing bibliometric networks: A comparison between full and fractional counting, Journal of Informetrics, 10, 4, pp. 1178-1195, (2016); Pessin V. Z., Yamane L. H., Siman R. R., Smart bibliometrics: An integrated method of science mapping and bibliometric analysis, Scientometrics, 127, 6, pp. 3695-3718, (2022); Raes F., Pommier E., Neff K. D., Van Gucht D., Construction and factorial validation of a short form of the self‐compassion scale, Clinical Psychology & Psychotherapy, 18, 3, pp. 250-255, (2011); Swami V., Andersen N., Furnham A., A bibliometric review of self-compassion research: Science mapping the literature, 1999 to 2020, Mindfulness, 12, 9, pp. 2117-2131, (2021); van Eck N. J., Waltman L., Citation-based clustering of publications using CitNetExplorer and VOSviewer, Scientometrics, 111, 2, pp. 1053-1070, (2017); van Raan A. F. J., Advances in bibliometric analysis: Research performance assessment and science mapping, Bibliometrics Use and Abuse in the Review of Research Performance, pp. 17-28, (2014); Wang J., Zhang S., Cross-cultural learning: A visualized bibliometric analysis based on bibliometrix from 2002 to 2021, Mobile Information Systems, 22, 1, (2022); Winders S. J., Murphy O., Looney K., O'Reilly G., Self‐compassion, trauma, and posttraumatic stress disorder: A systematic review, Clinical Psychology & Psychotherapy, 27, 3, pp. 300-329, (2020); Yarnell L. M., Stafford R. E., Neff K. D., Reilly E. D., Knox M. C., Mullarkey M., Meta-analysis of gender differences in self-compassion, Self and Identity, 14, 5, pp. 499-520, (2015)","C. Boonroungrut; Faculty of Education, Silpakorn University, Thailand; email: boonroungrut_c@su.ac.th","","Hong Kong Bao Long Accounting And Secretarial Limited","","","","","","20737904","","","","English","Knowl. Manage. E-Learn.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85209548157" -"Kudinska M.; Solovjova I.; Korde Ž.","Kudinska, Marina (57190119984); Solovjova, Irina (57191835221); Korde, Žanete (58793847900)","57190119984; 57191835221; 58793847900","Research trends in the field of sport impact on the economy: a bibliometric analysis","2025","Frontiers in Sports and Active Living","7","","1545264","","","","0","10.3389/fspor.2025.1545264","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105005580410&doi=10.3389%2ffspor.2025.1545264&partnerID=40&md5=d4bd47d984102403a4e53d098ac22d5e","Department of Finance and Accounting, University of Latvia, Riga, Latvia; Department of Health Psychology and Pedagogy, Riga Stradinš University, Riga, Latvia","Kudinska M., Department of Finance and Accounting, University of Latvia, Riga, Latvia; Solovjova I., Department of Finance and Accounting, University of Latvia, Riga, Latvia; Korde Ž., Department of Health Psychology and Pedagogy, Riga Stradinš University, Riga, Latvia","In this paper, the authors summarize the results of the bibliometric analysis. The object of the analysis is scientific publications published in the Scopus database in the scientific field of the impact of sports on the economy. The study aims to fill the research gap in the bibliometric analysis of the impact of sports on the economy by providing an empirical contribution that reveals trends in the scientific literature on the impact of sports on the economy, the most productive researchers, institutions, countries, journals in this field of research, and identifying a bibliometric framework that includes networks between researchers. Scientific articles indexed in Scopus were analyzed with no specific time limits using bibliometric analysis methods—performance analysis, citation analysis, and science mapping. We employed performance analysis, citation analysis, and science mapping via the Bibliometrix package R Studio® and the VOSviewer. The results of the systematic review show that, according to the Scopus database, 801 authors have studied the impact of sports on the global economy, and 299 scientific articles have been published in various journals around the world during the study period. This relatively low number suggests insufficient attention on the part of researchers to the importance of the sports sector. The most active researchers are from the USA, the UK, and China. The most influential journals and research institutions have been identified. The study results showed disagreement between the authors in some areas of the study (economic impact of major sporting events, impact of new sports infrastructure on regional economic growth, illustrating the ongoing debates in the field. 2025 Kudinska, Solovjova and Korde.","analysis; bibliometric; impact; publications; scopus; sports","","","","","","","","Pirina M.G., Farooq M., Solinas R., Marcia-Andreu M.J., Quero-Calero C.D., Galardo A.M., Et al., Bibliometric analysis of sports management competencies in women’s semi-professional sport: a comprehensive analysis at the literature with data visualization software, Procedia Comput Sci, 239, C, pp. 1568-1577, (2024); Chiu W., Cho H., Won D., The knowledge structure of corporate social responsibility in sport management: a retrospective bibliometric analysis, Int J Sports Mark Spons, 24, 4, pp. 771-792, (2023); Belfiore P., Iovino S., Tafuri D., Sport management and educational management: a bibliometric analysis, Sport Science, 12, 1, pp. 61-6415, (2019); Plaza-Navas M.A., Prunonosa J.T., Diez-Martin F., Prado-Roman C., The sources of knowledge of the economic and social value in sport industry research: a co-citation analysis, Front Psychology, 11, pp. 1-17, (2020); Gholampour S., Elahi A., Gholampour B., Noruzi A., Research trends and bibliometric analysis of a journal: sport management review, Webology, 16, 2, (2019); Keskin M.T., Ulusay N., Ozer S.C., Ulusay M., Evaluating scientific publications in the field of sports management: a bibliometric study based on the web of science database, Retos, 60, pp. 140-155, (2024); Zhou T., Bibliometric analysis and visualization of online education in sports, Cogent Soc Sci, 9, 1, pp. 1-14, (2023); Dindorf C., Bartaguiz E., Gassmann F., Frohlich M., Сonceptual structure and current trends in artificial intelligence, machine learning, and deep learning research in sports: a bibliometric review, Int J Environ Res Public Health, 20, 1, (2023); Alcoser S.D., Alencar A., Backes A.F., Vieira J., Teaching models of sport: a bibliometric study, Retos, 50, pp. 936-942, (2023); Moradi E., Gholampour S., Gholampour B., Past, present and future of sport policy: a bibliometric analysis of international journal of sport policy and politics (2010–2022), Int J Sport Policy Politics, 15, 4, pp. 577-602, (2023); Zhilong Z., Shengping Y., Tianxin C., Yuqi Z., Research hotspots and trends in the field of articular cartilage repair: a visualization analysis, Chin J Tissue Eng Res, 28, 27, pp. 4306-4300, (2024); Liu X., Liu D., Opoku M., Lu W., Pan L., Li Y., Et al., A bibliometric and visualized analysis of meniscus suture based on the WOS core collection from 2010 to 2022: a review, Medicine (Baltimore), 102, 46, (2023); Yildiz K., Eroglu Y., Besikci T., A bibliometric analysis of outdoor education, Revista Romaneasca Pentru Educatie Multidimensionala, 14, 1Sup1, pp. 275-288, (2022); Van Eck N.J., Waltman L., Software survey: vOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, pp. 523-538, (2010); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, J Informetr, 11, 4, pp. 959-975, (2017); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W., How to conduct a bibliometric analysis: an overview and guidelines, J Bus Res, 133, pp. 285-296, (2021); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E.F., Herrera F., Science mapping software tools: review, analysis, and cooperative study among tools, J Am Soc Inf Sci Technol, 62, 7, pp. 1382-1402, (2011); Baade R.A., Dye R.F., The impact of stadium and professional sports on metropolitan area developmen, Growth Change, 21, 2, pp. 1-14, (1990); Egghe L., Theory and practice of the G-index, Scientometrics, 69, 1, pp. 131-152, (2006); Baade R.A., Matheson V.A., An Evaluation of the Economic Impact of National Football League Mega-events, pp. 11-19, (2012); Matheson V.A., Economic multipliers and mega-event analysis, International Journal of Sport Finance, 4, 1, pp. 63-70, (2009); Matheson V.A., The quest for the cup: assessing the economic impact of the world cup, Reg Stud, 38, 4, pp. 343-354, (2004); Matheson V.A., Mega-Events: The Effect of the World’s Biggest Sporting Events on Local, Regional, and National Economies, Working Papers 0622, International Association of Sports Economists, (2006); Matheson V.A., Baumann R., Baade R., Selling the game: estimating the economic impact of professional sports through taxable sales, South Econ J, 74, 3, pp. 794-810, (2008); Matheson V.A., The rise and fall of the olympic games as an economic driver, (2018); Coates D., Humphreys B.R., The growth effects of sport franchises, stadia, and arenas, J Policy Anal Manag, 18, 4, pp. 601-624, (1999); Humphreys B.R., Prokopowicz S., Assessing the impact of sports mega-events in transition economies: eURO 2012 in Poland and Ukraine, Int J Sport Manag Mark, 2, 5-6, pp. 496-509, (2007); Coates D., Humphreys B.R., The effect of professional sports on earnings and employment in the services and retail sectors in US cities, 3/1, J Reg Sci Urban Econ, 33, 2, pp. 175-198, (2003); Zhang J., Wei X., Lyulyov O., Pimanenko T., The role of digital economy in enhancing the sports industry to attain sustainable development, Sustainability, 15, 15, (2023); Zhang J., Du R., Super bowl participation and the local economy: evidence from the stock market, Growth Change, 53, 4, pp. 1513-1545, (2021); Agha N., Rascher D., An explanation of economic impact: why positive impacts can exist for smaller sports, Sport Bus Manag: Int J, 6, 2, pp. 182-204, (2012); Wu B., Discussion on the development of sports industry in China based on the perspective of “low carbon economy, Appl Math Nonlinear Sci, 9, 1, pp. 1-18, (2024); Navarro S., Perez Y.S., Pirela R.A.V., Incidence of sport on economic growth in Colombia, Retos, 51, pp. 1101-1109, (2024); Han L., Zhang D., Hua X., Assessing the coordinative and coupling development of China’s green economic growth: role of sports economics, Econ Res-Ekon Istraz, 36, 3, pp. 1-21, (2023); Zhao S., Sun J., Design of sports event evaluation and classification method based on deep neural network, Comput Intell Neurosci, pp. 1-10, (2022); Crespo S.P., Economic and social yield of investing in a sporting event: sustainable value creation in a territory, Sustainability, 13, 13, pp. 1-15; Firgo M., The causal economic effects of Olympic games on host regions, Reg Sci Urban Econ, 88, (2021); Impact Score, (2024); Baker H.K., Kumar S., Pandey N., A bibliometric analysis of managerial finance: a retrospective, Managerial Finance, 46, 11, (2020); Glanzel W., Schoepflin U., A bibliometric study of reference literature in the sciences and social sciences, Inf Process Manag, 35, pp. 31-44, (1999); Opolska I., Proskina L., Sports Role in Economics, pp. 322-329, (2017); Zimbalist A., The organization and economics of sports mega-events, Intereconomics, 51, pp. 110-111, (2016); Li S., Jago L., Evaluating economic impacts of major sports events - A meta-analysis of the key trends, Curr Issues Tourism, 16, 6, pp. 591-611, (2013); Knott B., Swart K., Visser S., The impact of sport mega-events on the quality of life for host city residents: reflections on the 2010 FIFA world cup, Afr J Hosp Tour Leis, 4, pp. 1-17, (2014); Wang L., Zhao F., Zhang G., Analysis on the impact of large-scale sports events on regional economy based on SWOT-PEST model, J Math, 2022, 2, pp. 1-12, (2022); Rusmane S., Kudinska M., The Role of Social Capital Within Sport Sector During an Ongoing Pandemic: The Perspective of the European Union. New Challenges in Economic and Business Development – 2022: Responsible Growth, pp. 160-167, (2022); Luo M., Chen L., The impact of sports industry agglomeration on the high-quality development of green energy, Front Environ Sci, 11, (2023); Mitchel I., The Importance of Sport to the Local Economies, (2024)","M. Kudinska; Department of Finance and Accounting, University of Latvia, Riga, Latvia; email: marina.kudinska@lu.lv","","Frontiers Media SA","","","","","","26249367","","","","English","Frontier. Sport. Act. Living.","Review","Final","","Scopus","2-s2.0-105005580410" -"Tchuente D.; Nyawa S.; Wamba S.F.","Tchuente, Dieudonne (25925535100); Nyawa, Serge (57210437787); Wamba, Samuel Fosso (14833520200)","25925535100; 57210437787; 14833520200","CoVId-19 Vaccine Global Information Management through Bibliometrics","2021","Journal of Global Information Management","29","6","","","","","2","10.4018/JGIM.294578","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85151807256&doi=10.4018%2fJGIM.294578&partnerID=40&md5=1e47a612360c3eb4d831209173e2df91","Toulouse Business School, France","Tchuente D., Toulouse Business School, France; Nyawa S., Toulouse Business School, France; Wamba S.F., Toulouse Business School, France","Vaccination is nowadays the most used option to stem the COVID-19 pandemic. The global impact of the pandemic has triggered an unprecedented frenzy for research axis related to the COVID-19 vaccine. Since 2019, the volume of publications related to COVID-19 vaccines has swollen significantly. In this very dynamic context, it can be difficult to quickly access the state and orientations of the research. Thus, the goal of this paper is to provide a quick, fast comprehensive science mapping of these studies through an information management bibliometric approach. The authors extracted 8,246 publications (up to July 8th, 2021) related to COVID-19 and vaccination from a world-leading publisher-independent global citation database (Scopus). The Bibliometrix package was then used to perform a bibliometric review of all these documents. The most important connections between the main themes, publications, authors, institutions, countries, collaborations, and journals are highlighted. Main implications for the information system along with some future research directions are also presented. © 2021 IGI Global. All rights reserved.","Bibliometric; COVID-19; Information Management; Review; SARS-COV-2; Vaccination; Vaccine","Information management; Vaccines; Bibliometric; Dynamic contexts; Future research directions; Global impacts; Global informations; SARS-COV-2; Vaccination; COVID-19","","","","","","","Ahmad T., Murad M. A., Baig M., Hui J., Research Trends in COVID-19 Vaccine: A Bibliometric Analysis, Human Vaccines & Immunotherapeutics, 17, 8, pp. 1-6, (2021); Ahmed S. F., Quadeer A. A., McKay M. R., Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies, Viruses, 12, 3, (2020); Amanat F., Krammer F., SARS-CoV-2 Vaccines: Status Report, Immunity, 52, 4, pp. 583-589, (2020); Aria M., Cuccurullo C., Bibliometrix: An R-Tool for Comprehensive Science Mapping Analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aristovnik A., Ravselj D., Umek L., A Bibliometric Analysis of COVID-19 across Science and Social Science Research Landscape, Sustainability, 12, 21, (2020); Baden L. R., Efficacy and Safety of the MRNA-1273 SARS-CoV-2 Vaccine, New England Journal of Medicine, 384, 5, pp. 403-416, (2021); Beydoun G., Abedin B., Merigo J. M., Vera M., Twenty Years of Information Systems Frontiers, Information Systems Frontiers, 21, 2, pp. 485-494, (2019); Bretas V. P. G., Alon I., Franchising Research on Emerging Markets: Bibliometric and Content Analyses, Journal of Business Research, 133, pp. 51-65, (2021); Understanding MRNA COVID-19 Vaccines, (2021); Chahrour M., Assi S., Bejjani M., Nasrallah A. A., Salhab H., Fares M. Y., Khachfe H. H., A Bibliometric Analysis of COVID-19 Research Activity: A Call for Increased Output, Cureus, 12, 3, (2020); Cobo M. J., Lopez-Herrera A. G., Herrera-Viedma E., Herrera F., An Approach for Detecting, Quantifying, and Visualizing the Evolution of a Research Field: A Practical Application to the Fuzzy Sets Theory Field, Journal of Informetrics, 5, 1, pp. 146-166, (2011); (2021); Dehghanbanadaki H., Seif F., Vahidi Y., Razi F., Hashemi E., Khoshmirsafa M., Aazami H., Bibliometric Analysis of Global Scientific Research on Coronavirus (COVID-19), Medical Journal of the Islamic Republic of Iran, 34, (2020); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to Conduct a Bibliometric Analysis: An Overview and Guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Donthu N., Kumar S., Pandey N., Gupta P., Forty Years of the International Journal of Information Management: A Bibliometric Analysis, International Journal of Information Management, 57, (2021); El-Elimat T., AbuAlSamen M. M., Almomani B. A., Al-Sawalha N. A., Alali F. Q., Acceptance and Attitudes toward COVID-19 Vaccines: A Cross-Sectional Study from Jordan, PLoS One, 16, 4, (2021); El Mohadab M., Bouikhalene B., Safi S., Bibliometric Method for Mapping the State of the Art of Scientific Production in Covid-19, Chaos, Solitons, and Fractals, 139, (2020); COVID-19 Vaccines: Development, Evaluation, Approval and Monitoring, (2021); Fassin Y., Research on Covid-19: A Disruptive Phenomenon for Bibliometrics, Scientometrics, 126, 6, pp. 5305-5319, (2021); Folegatti P. M., Safety and Immunogenicity of the ChAdOx1 NCoV-19 Vaccine against SARS-CoV-2: A Preliminary Report of a Phase 1/2, Single-Blind, Randomised Controlled Trial, The Lancet, 396, 10249, pp. 467-478, (2020); Forliano C., De Bernardi P., Yahiaoui D., Entrepreneurial Universities: A Bibliometric Analysis within the Business and Management Domains, Technological Forecasting and Social Change, 165, (2021); Gonzalez-Perez M., Sanchez-Tarjuelo R., Shor B., Nistal-Villan E., Ochando J., The BCG Vaccine for COVID-19: First Verdict and Future Directions, Frontiers in Immunology, 12, (2021); Grifoni A., Weiskopf D., Ramirez S. I., Mateus J., Dan J. M., Moderbacher C. R., Rawlings S. A., Sutherland A., Premkumar L., Jadi R. S., Marrama D., de Silva A. M., Frazier A., Carlin A. F., Greenbaum J. A., Peters B., Krammer F., Smith D. M., Crotty S., Sette A., Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals, Cell, 181, 7, pp. 1489-1501, (2020); Hamidah I., Sriyono S., Hudha M. N., A Bibliometric Analysis of Covid-19 Research Using VOSviewer, Indonesian Journal of Science and Technology, 5, 2, pp. 209-216, (2020); Jackson L. A., An MRNA Vaccine against SARS-CoV-2—Preliminary Report, New England Journal of Medicine, (2020); Kaur S. P., Gupta V., COVID-19 Vaccine: A Comprehensive Status Report, Virus Research, 288, (2020); Le T. T., The COVID-19 Vaccine Development Landscape, Nat Rev Drug Discov, 19, 5, pp. 305-306, (2020); Li X., Geng M., Peng Y., Meng L., Lu S., Molecular Immune Pathogenesis and Diagnosis of COVID-19, Journal of Pharmaceutical Analysis, 10, 2, pp. 102-108, (2020); Liu C., Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases, (2020); Lopez-Robles Otegi-Olaso, Gomez Porto, Cobo, 30 Years of Intelligence Models in Management and Business: A Bibliometric Review, International Journal of Information Management, 48, pp. 22-38, (2019); Lou J., Coronavirus Disease 2019: A Bibliometric Analysis and Review, European Review for Medical and Pharmacological Sciences, 24, 6, pp. 3411-3421, (2020); Lurie N., Saville M., Hatchett R., Halton J., Developing Covid-19 Vaccines at Pandemic Speed, The New England Journal of Medicine, 382, 21, pp. 1969-1973, (2020); Madjid M., Safavi-Naeini P., Solomon S. D., Vardeny O., Potential Effects of Coronaviruses on the Cardiovascular System: A Review, JAMA Cardiology, 5, 7, pp. 831-840, (2020); Mapping the Situation of Research on Coronavirus Disease-19 (COVID-19): A Preliminary Bibliometric Analysis during the Early Stage of the Outbreak, BMC Infectious Diseases, 20, 1, pp. 1-8, (2020); Nicola M., Alsafi Z., Sohrabi C., Kerwan A., Al-Jabir A., Iosifidis C., Agha M., Agha R., The Socio-Economic Implications of the Coronavirus Pandemic (COVID-19): A Review, International Journal of Surgery, 78, pp. 185-193, (2020); Ou X., Liu Y., Lei X., Li P., Mi D., Ren L., Guo L., Guo R., Chen T., Hu J., Xiang Z., Mu Z., Chen X., Chen J., Hu K., Jin Q., Wang J., Qian Z., Characterization of Spike Glycoprotein of SARS-CoV-2 on Virus Entry and Its Immune Cross-Reactivity with SARS-CoV, Nature Communications, 11, 1, pp. 1-12, (2020); Polack F. P., Safety and Efficacy of the BNT162b2 MRNA Covid-19 Vaccine, New England Journal of Medicine, (2020); Prompetchara E., Ketloy C., Palaga T., Immune Responses in COVID-19 and Potential Vaccines: Lessons Learned from SARS and MERS Epidemic, Asian Pacific Journal of Allergy and Immunology, 38, 1, pp. 1-9, (2020); Shi J., Duan K., Wu G., Zhang R., Feng X., Comprehensive Metrological and Content Analysis of the Public–Private Partnerships (PPPs) Research Field: A New Bibliometric Journey, Scientometrics, 124, 3, pp. 2145-2184, (2020); Srivastava P. R., Intellectual Structure and Publication Pattern in Journal of Global Information Management: A Bibliometric Analysis During 2002-2020, Journal of Global Information Management, 29, 4, pp. 1-31, (2021); Tai W., He L., Zhang X., Pu J., Voronin D., Jiang S., Zhou Y., Du L., Characterization of the Receptor-Binding Domain (RBD) of 2019 Novel Coronavirus: Implication for Development of RBD Protein as a Viral Attachment Inhibitor and Vaccine, Cellular & Molecular Immunology, 17, 6, pp. 613-620, (2020); Tian X., Li C., Huang A., Xia S., Lu S., Shi Z., Lu L., Jiang S., Yang Z., Wu Y., Ying T., Potent Binding of 2019 Novel Coronavirus Spike Protein by a SARS Coronavirus-Specific Human Monoclonal Antibody, Emerging Microbes & Infections, 9, 1, pp. 382-385, (2020); Varsha P. S., The Impact of Artificial Intelligence on Branding: A Bibliometric Analysis (1982-2019), Journal of Global Information Management, 29, 4, pp. 221-246, (2021); Veiga, Teixeira, Fernandes C. I. I., Opening Pandora’s Box: Everything We (Do Not) Know About the Global Strategy, Journal of Global Information Management, 29, 1, pp. 1-21, (2021); Voysey M., Clemens S. A. C., Madhi S. A., Weckx L. Y., Folegatti P. M., Aley P. K., Angus B., Baillie V. L., Barnabas S. L., Bhorat Q. E., Bibi S., Briner C., Cicconi P., Collins A. M., Colin-Jones R., Cutland C. L., Darton T. C., Dheda K., Duncan C. J. A., Zuidewind P., Et al., Safety and Efficacy of the ChAdOx1 NCoV-19 Vaccine (AZD1222) against SARS-CoV-2: An Interim Analysis of Four Randomised Controlled Trials in Brazil, South Africa, and the UK, Lancet, 397, 10269, pp. 99-111, (2021); Wamba S. F., Are We Preparing for a Good AI Society? A Bibliometric Review and Research Agenda, Technological Forecasting and Social Change, 164, (2021); Wang P., Tian D., Bibliometric Analysis of Global Scientific Research on COVID-19, Journal of Biosafety and Biosecurity, 3, 1, pp. 4-9, (2021); Wang Y., Wang Y., Chen Y., Qin Q., Unique Epidemiological and Clinical Features of the Emerging 2019 Novel Coronavirus Pneumonia (COVID‐19) Implicate Special Control Measures, Journal of Medical Virology, 92, 6, pp. 568-576, (2020); COVID-19 Vaccines, (2021); Wiersinga W. J., Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review, JAMA, 324, 8, pp. 782-793, (2020); WHO Coronavirus Disease (COVID-19) Dashboard: World Health Organization, (2021); Wu K. J., Zimmer C., Corum J., Coronavirus Drug and Treatment Tracker, (2021); Zhang L., Liu Y., Potential Interventions for Novel Coronavirus in China: A Systematic Review, Journal of Medical Virology, 92, 5, pp. 479-490, (2020)","","","IGI Global","","","","","","10627375","","","","English","J. Global Inf. Manage.","Article","Final","All Open Access; Bronze Open Access","Scopus","2-s2.0-85151807256" -"Wang X.; Yang Y.; Lv J.; He H.","Wang, Xiangwei (57958725800); Yang, Yizhe (57794078200); Lv, Jianglong (55576905300); He, Hailong (55609353200)","57958725800; 57794078200; 55576905300; 55609353200","Past, present and future of the applications of machine learning in soil science and hydrology","2023","Soil and Water Research","18","2","","67","80","13","18","10.17221/94/2022-SWR","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85164016707&doi=10.17221%2f94%2f2022-SWR&partnerID=40&md5=1cd47b9845c4ab2c5a0fc27c91bda54f","College of Natural Resources and Environment, Northwest A&F University, Shaanxi, Yangling, China; Shaanxi Provincial Farmland Quality and Agricultural Environmental Protection Workstation, Department of Agriculture and Rural Affairs of Shaanxi Province, Shaanxi, Xi’an, China; Key Laboratory of Plant Nutrition and the Agri-Environment in Northwest China (Ministry of Agriculture), Northwest A&F University, Yangling, China","Wang X., College of Natural Resources and Environment, Northwest A&F University, Shaanxi, Yangling, China; Yang Y., Shaanxi Provincial Farmland Quality and Agricultural Environmental Protection Workstation, Department of Agriculture and Rural Affairs of Shaanxi Province, Shaanxi, Xi’an, China; Lv J., College of Natural Resources and Environment, Northwest A&F University, Shaanxi, Yangling, China, Key Laboratory of Plant Nutrition and the Agri-Environment in Northwest China (Ministry of Agriculture), Northwest A&F University, Yangling, China; He H., College of Natural Resources and Environment, Northwest A&F University, Shaanxi, Yangling, China, Key Laboratory of Plant Nutrition and the Agri-Environment in Northwest China (Ministry of Agriculture), Northwest A&F University, Yangling, China","Machine learning can handle an ever-increasing amount of data with the ability to learn models from the data. It has been widely used in a variety of disciplines and is gaining increasingly more attention nowadays. As it is challenging to map soil and hydrological information that are characterised with high spatial and temporal variability, applications of machine learning in soil science and hydrology (AMLSH) have become popularised. To better understand the current state of AMLSH research, a scientific and quantitative approach was performed to statistically analyse publication information from 1973 to 2021 archived in the Scopus database using scientometric analysis tools, including VOSviewer, CiteSpace, and the open-source R package “bibliometrix”. The results show a significant increase in the number of publications on AMLSH since 2006. The major contributions were identified based on country origins (China, the USA, and India), institutions (Hohai University, Islamic Azad University, and Wuhan University), and journals (Journal of Hydrology, Remote Sensing, and Geoderma). The keywords analysis of the AMLSH research demonstrates four research hotspots: neural network, artificial intelligence, machine learning, and soil. The most frequently utilised machine learning (ML) methods are neural networks, decision trees, random forests and other methods for image processing and predictive analysis. McBratney et al. 2003 is the most highly cited article. Our research sheds light on the research process on AMLSH and concludes with future research perspectives. © The authors.","machine learning; science mapping; scientometric analysis; soil","","","","","","","","Abraham A., Pedregosa F., Eickenberg M., Gervais P., Mueller A., Kossaifi J., Gramfort A., Thirion B., Varoquaux G., Machine learning for neuroirnaging with scikitlearn, Frontiers in Neuroinformatics, 8, (2014); Acker A., Toward a hermeneutics of data, Ieee Annals of the History of Computing, 3, pp. 70-75, (2015); Aha D.W., Kibler D., Albert M.K., Instance-based learning algorithms, Machine Learning, 1, pp. 37-66, (1991); Ao Y.L., Li H.Q., Zhu L.P., Ali S., Yang Z.G., The linear random forest algorithm and its advantages in machine learning assisted logging regression modeling, Journal of Petroleum Science and Engineering, 174, pp. 776-789, (2019); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 4, pp. 959-975, (2017); Ayoubi S., Karchegani P.M., Determination the factors explaining variability of physical soil organic carbon fractions using Artificial Neural Network, International Journal of Soil Science, 1, pp. 1-14, (2012); Azadmard B., Mosaddeghi M.R., Ayoubi S., Chavoshi E., Raoof M., Estimation of near-saturated soil hydraulic properties using hybrid genetic algorithm-artificial neural network, Ecohydrology and Hydrobiology, 3, pp. 437-449, (2020); Baskaya O., Jurgens D., Semi-supervised learning with induced word senses for state of the art word sense disambiguation, Journal of Artificial Intelligence Research, 55, pp. 1025-1058, (2016); Besalatpour A., Hajabbasi M.A., Ayoubi S., Gharipour A., Jazi A.Y., Prediction of soil physical properties by optimized support vector machines, International Agrophysics, 2, pp. 109-115, (2012); Besalatpour A.A., Ayoubi S., Hajabbasi M.A., Mosaddeghi M.R., Schulin R., Estimating wet soil aggregate stability from easily available properties in a highly mountainous watershed, Catena, 111, pp. 72-79, (2013); Bonakdari H., Ebtehaj I., Samui P., Gharabaghi B., Lake water-level fluctuations forecasting using Mini-max Probability Machine Regression, Relevance Vector Machine, Gaussian Process Regression, and Extreme Learning Machine, Water Resources Management, 11, pp. 3965-3984, (2019); Brillinger D.R., Fourier inference: Some methods for the analysis of array and nongaussian series data, JAWRA Journal of the American Water Resources Association, 5, pp. 743-756, (1985); Brungard C.W., Boettinger J.L., Duniway M.C., Wills S.A., Edwards T.C., Machine learning for predicting soil classes in three semi-arid landscapes, Geoderma, 239, pp. 68-83, (2015); Bui D.T., Tsangaratos P., Nguyen V.T., Liem N.V., Trinh P.T., Comparing the prediction performance of a Deep Learning Neural Network model with conventional machine learning models in landslide susceptibility assessment, Catena, 188, (2020); Burrough P.A., Principles of geographical information systems for land resources assessment, Geocarto International, 1, (1986); Buszewski B., Kowalkowski T., A new model of heavy metal transport in the soil using nonlinear artificial neural networks, Environmental Engineering Science, 4, pp. 589-595, (2006); Certes C., Hubert P., Application de la programmation logique en hydrologie. 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Zolfaghari Z., Mosaddeghi M.R., Ayoubi S., ANN-based pedotransfer and soil spatial prediction functions for predicting Atterberg consistency limits and indices from easily available properties at the watershed scale in western Iran, Soil Use and Management, 1, pp. 142-154, (2015)","H. He; College of Natural Resources and Environment, Northwest A&F University, Yangling, Shaanxi, China; email: hailong.he@hotmail.com","","Czech Academy of Agricultural Sciences","","","","","","18015395","","","","English","Soil Water Res.","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85164016707" -"Malekolkalami M.; Hassanzadeh M.; Sharif A.; Rezghi Ahaghi M.","Malekolkalami, Mila (56054343900); Hassanzadeh, Mohammad (55386956600); Sharif, Atefeh (56055068000); Rezghi Ahaghi, Mansoor (9536926000)","56054343900; 55386956600; 56055068000; 9536926000","Cluster Analysis of Knowledge Development in the Field of Knowledge Extraction in Service Industry","2023","Scientometrics Research Journal","9","2","","445","470","25","0","10.22070/rsci.2022.16414.1599","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85217032009&doi=10.22070%2frsci.2022.16414.1599&partnerID=40&md5=346ae50e3f72b5f6a73d09f49c4da342","Knowledge Management, Management and Economics Faculty, Tarbiat Modares University, Tehran, Iran; Department of Mathematics, Tarbiat Modares University, Tehran, Iran","Malekolkalami M., Knowledge Management, Management and Economics Faculty, Tarbiat Modares University, Tehran, Iran; Hassanzadeh M., Knowledge Management, Management and Economics Faculty, Tarbiat Modares University, Tehran, Iran; Sharif A., Knowledge Management, Management and Economics Faculty, Tarbiat Modares University, Tehran, Iran; Rezghi Ahaghi M., Department of Mathematics, Tarbiat Modares University, Tehran, Iran","Purpose: Service industries are recognized as one of the largest sectors of the economy globally, and it has the most prominent role in the coun-tries' economic growth. To create an essential change that represents a revolutionary change in the technology of a product or service, there is a need to acquire, extract and develop knowledge to achieve a competitive advantage. Therefore, this study aims to analyze the knowledge development clusters in the service industry's knowledge extraction field. In the knowledge management process, knowledge extraction is the main phase of knowledge acquisition. Knowledge acquisition is one of the important aspects of knowledge discovery in databases to help managers make timely decisions by extracting correct knowledge. Methodology: Bibliometrics and scientific mapping techniques have been used in this applied research. Research data were collected from the Scopus database from 1986 to 2022. VOSviewer and Bibliometrix R were used to analyze and visualize data and scientific maps. Furthermore, to ensure the accuracy and validity of the results, Bibliometrix and Excel tools have been used to integrate data and remove duplicate data. Findings: The research findings show the knowledge extraction application among 434 documents in 5 clusters of knowledge extraction, artificial intelligence, information retrieval, semantics, and forecasting. In the research, knowledge extraction and data mining are the most widely used words in a single cluster and have the most centrality and betweenness. Likewise, the bibliometric analysis of the data in The Multiple Correspondence Analysis (MCA) shows that the Internet, natural language processing, and machine learning are among the topics that are important next to the healthcare sector. This shows the importance of natural language and machine learning in extracting knowledge in healthcare ser-vices. Since 2006, the importance of knowledge extraction has received more attention. The co-occurrence of keywords shows that knowledge extraction is widely used with data mining, extraction, and artificial intel-ligence. The keywords of knowledge extraction and data mining in cluster 1, semantics, knowledge management, and information services in cluster 2, and information retrieval, internet, and human in cluster 3 have the highest centrality. The theme mapping shows that forecasting, multi-agent systems, and planning are themes with high density and low cen-trality, which are called niche themes. Semantics, web services, and knowledge-based systems are the main themes with low density and high centrality. Also, artificial intelligence, information management, and decision support systems are themes with low density and centrality, which are also known as emerging or declining themes. The forecasting cluster is located in the strategic knowledge cluster group. Information retrieval, knowledge extraction, and artificial intelligence are included in the cluster of practical knowledge. Semantics as a cluster including various experts and specialists such as domain experts, knowledge engineers, and programmers is in the collaborative cluster. Conclusion: Knowledge extraction is an emerging interdisciplinary field in knowledge management and has a direct and significant impact on the country's economy. Knowledge development and integration of key issues in knowledge extraction are essential. According to the findings of this study, for the promotion and advancement of this process in the service industry, it is suggested to provide a strategic view in the use of metadata analysis of the context of activity and success of the service industry in knowledge extraction. Moreover, knowledge management as the primary discipline and domain can guarantee success in this process. The clusters identified in this study are also divided into three practical, strategic, and collaborative knowledge clusters. Moreover, the results of this research can help managers of organizations, especially their knowledge managers, to plan and make decisions in the field of service industries to facilitate optimal knowledge extraction and maintain competitive advantage. © 2023, Shahed University. All rights reserved.","Bibliometrics; Knowledge Cluster; Knowledge Extraction; Knowledge Management; Science Mapping; Service Industry; Thematic Mapping","","","","","","","","Ahmed E. F. I., Comparative Study Between Naive Bayes and REP Tree Algorithms for Eye Refractive Error, (2018); Alcayde-Garcia F., Salmeron-Manzano E., Montero M. A., Alcayde A., Manzano-Agugliaro F., Power Transmission Lines: Worldwide Research Trends, Energies, 15, 16, (2022); Alsharif A. H., Md Salleh N. 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J.","Article","Final","","Scopus","2-s2.0-85217032009" -"Sajovic I.; Kert M.; Boh Podgornik B.","Sajovic, Irena (57193269832); Kert, Mateja (6506299574); Boh Podgornik, Bojana (57211311325)","57193269832; 6506299574; 57211311325","Smart Textiles: A Review and Bibliometric Mapping","2023","Applied Sciences (Switzerland)","13","18","10489","","","","27","10.3390/app131810489","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85172998724&doi=10.3390%2fapp131810489&partnerID=40&md5=fa31a6e8437840ee5eb883710d684f77","Faculty of Natural Sciences and Engineering, Department of Textiles, Graphic Arts and Design, University of Ljubljana, Aškerčeva cesta 12, Ljubljana, 1000, Slovenia","Sajovic I., Faculty of Natural Sciences and Engineering, Department of Textiles, Graphic Arts and Design, University of Ljubljana, Aškerčeva cesta 12, Ljubljana, 1000, Slovenia; Kert M., Faculty of Natural Sciences and Engineering, Department of Textiles, Graphic Arts and Design, University of Ljubljana, Aškerčeva cesta 12, Ljubljana, 1000, Slovenia; Boh Podgornik B., Faculty of Natural Sciences and Engineering, Department of Textiles, Graphic Arts and Design, University of Ljubljana, Aškerčeva cesta 12, Ljubljana, 1000, Slovenia","According to ISO/TR 23383, smart textiles reversibly interact with their environment and respond or adapt to changes in the environment. The present review and bibliometric analysis was performed on 5810 documents (1989–2022) from the Scopus database, using VOSviewer and Bibliometrix/Biblioshiny for science mapping. The results show that the field of smart textiles is highly interdisciplinary and dynamic, with an average growth rate of 22% and exponential growth in the last 10 years. Beeby, S.P., and Torah, R.N. have published the highest number of papers, while Wang, Z.L. has the highest number of citations. The leading journals are Sensors, ACS Applied Materials and Interfaces, and Textile Research Journal, while Advanced Materials has the highest number of citations. China is the country with the most publications and the most extensive cooperative relationships with other countries. Research on smart textiles is largely concerned with new materials and technologies, particularly in relation to electronic textiles. Recent research focuses on energy generation (triboelectric nanogenerators, thermoelectrics, Joule heating), conductive materials (MXenes, liquid metal, silver nanoparticles), sensors (strain sensors, self-powered sensors, gait analysis), speciality products (artificial muscles, soft robotics, EMI shielding), and advanced properties of smart textiles (self-powered, self-cleaning, washable, sustainable smart textiles). © 2023 by the authors.","bibliometric analysis; hotspots; research trends; science mapping; smart textiles","","","","","","Slovenian Research and Innovation Agency; Center for Advancing Research Impact in Society, ARIS, (P2-0213); Center for Advancing Research Impact in Society, ARIS","This research was supported by the Slovenian Research and Innovation Agency (ARIS), project Grant No. P2-0213 Textiles and ecology.","Rijavec T., Standardisation of Smart Textiles, Glas. Hemičara Tehnol. Ekol. Repub. 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Nano Mater, 6, pp. 14656-14668, (2023); Yu B., Long J., Huang T., Xiang Z., Liu M., Zhang X., Zhu J., Yu H., Core–Sheath Fiber-Based Triboelectric Nanogenerators for Energy Harvesting and Self-Powered Straight-Arm Sit-Up Sensing, ACS Omega, 8, pp. 31427-31435, (2023); Ma L., Wu R., Patil A., Yi J., Liu D., Fan X., Sheng F., Zhang Y., Liu S., Shen S., Et al., Acid and Alkali-Resistant Textile Triboelectric Nanogenerator as a Smart Protective Suit for Liquid Energy Harvesting and Self-Powered Monitoring in High-Risk Environments, Adv. Funct. Mater, 31, (2021); Wang S., Liu S., Zhou J., Li F., Li J., Cao X., Li Z., Zhang J., Li B., Wang Y., Et al., Advanced Triboelectric Nanogenerator with Multi-Mode Energy Harvesting and Anti-Impact Properties for Smart Glove and Wearable e-Textile, Nano Energy, 78, (2020); Liu S., Zhang M., Kong J., Li H., He C., Flexible, Durable, Green Thermoelectric Composite Fabrics for Textile-Based Wearable Energy Harvesting and Self-Powered Sensing, Compos. Sci. Technol, 243, (2023); Fan X., Zhang X., Zhang X., Shiu B.-C., Lin J.-H., Lou C.-W., Li T.-T., Energy Filtering Effect of Flexible Organic/Inorganic Nanocomposite Thermoelectric Fabrics to Harvest Human Heat and Solar Energy, Polymer, 283, (2023); Zhu Z., Lin Z., Zhai W., Kang X., Song J., Lu C., Jiang H., Chen P., Sun X., Wang B., Et al., Indoor Photovoltaic Fiber with An Efficiency of 25.53% Under 1500 Lux Illumination, Adv. Mater, (2023); Abeywickrama N., Kgatuke M., Marasinghe K., Nashed M.N., Oliveira C., Shahidi A.M., Dias T., Hughes-Riley T., The Design and Development of Woven Textile Solar Panels, Materials, 16, (2023); Ke H., Gao M., Li S., Qi Q., Zhao W., Li X., Li S., Kuvondikov V., Lv P., Wei Q., Et al., Advances and Future Prospects of Wearable Textile- and Fiber-Based Solar Cells, Sol. RRL, 7, (2023); Park J., Chang S.-M., Shin J., Oh I.W., Lee D.-G., Kim H.S., Kang H., Park Y.S., Hur S., Kang C.-Y., Et al., Bio-Physicochemical Dual Energy Harvesting Fabrics for Self-Sustainable Smart Electronic Suits, Adv. Energy Mater, 13, (2023); Xie F., Mei D., Qiu L., Su Z., Chen L., Liu Y., Du P., High-Efficiency Fiber-Shaped Perovskite Solar Cells with TiO2/SnO2 Double-Electron Transport Layer Materials, J. Electron. Mater, 52, pp. 4626-4633, (2023); Zhao J., Lo L.-W., Yu Z., Wang C., Handwriting of Perovskite Optoelectronic Devices on Diverse Substrates, Nat. Photonics, (2023); Zhang L., Zhang W., Lan X., Zhao C., Fu J., Li Y., Feng Y., Yong Z., Guo J., Liu C., Et al., High-Energy-Density Fiber-Shaped Aqueous Ni//Fe Battery Enabled by Metal-Organic Framework Derived Spindle-Like Carbon Incorporated Iron Disulfide, SSRN, (2023); Tu H., Li X., Lin X., Lang C., Gao Y., Washable and Flexible Screen-Printed Ag/AgCl Electrode on Textiles for ECG Monitoring, Polymers, 15, (2023)","I. Sajovic; Faculty of Natural Sciences and Engineering, Department of Textiles, Graphic Arts and Design, University of Ljubljana, Ljubljana, Aškerčeva cesta 12, 1000, Slovenia; email: irena.sajovic@ntf.uni-lj.si","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20763417","","","","English","Appl. Sci.","Review","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85172998724" -"Maharani I.A.K.; Usman I.","Maharani, Ida Ayu Kartika (57371438900); Usman, Indrianawati (57201718428)","57371438900; 57201718428","The First 17 Years of the Journal of Management, Spirituality, and Religion (JMSR): Bibliometric Overview","2023","Journal of Management, Spirituality and Religion","20","3","","206","229","23","4","10.51327/LWUW8903","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163816438&doi=10.51327%2fLWUW8903&partnerID=40&md5=2fd324af39c593024e1416b5be96fd0a","Universitas Airlangga, Surabaya, Indonesia","Maharani I.A.K., Universitas Airlangga, Surabaya, Indonesia; Usman I., Universitas Airlangga, Surabaya, Indonesia","The Journal of Management, Spirituality, and Religion (JMSR) has been a leading scientific source for scholars interested in the religious and spiritual aspects of managing human capital in organizations. It was created to connect the concepts of spirituality and religiosity to increase awareness of people's spirituality and spiritual leadership in a business setting. It was also, to comprehend the effects of pluralism on organizations as a whole and the critical and distinct role of the various religious views held and the spirituality of each individual. This study uses bibliometric analysis techniques to retrieve all publications from the Scopus database from 2004 to 2020 to honor the 17 years of the JMSR's journey. The current study was carried out to highlight the JMSR's growth, development, and intellectual structure in terms of impact, citations, theme, topic trend evolution, most contributing universities, and collaboration network. © 2022 Association of Management, Spirituality & Religion.","Bibliometric; Bibliometrix; JMSR; performance analysis; science mapping; VOSViewer","","","","","","","","Afsar B., Rehman M., The relationship between workplace spirituality and innovative work behavior: The mediating role of perceived person-organization fit, Journal of Management, Spirituality and Religion, 12, 4, pp. 329-353, (2015); Agarwala R., Mishra P., Singh R., Religiosity and consumer behavior: a summarizing review, Journal of Management, Spirituality and Religion, 16, 1, pp. 32-54, (2019); Aksnes D., Sivertsen G., A Criteria-based Assessment of the Coverage of Scopus and Web of Science, Journal of Data and Information Science, 4, pp. 1-21, (2019); Aksnes D. W., Langfeldt L., Wouters P., Citations, Citation Indicators, and Research Quality: An Overview of Basic Concepts and Theories, SAGE Open, 9, 1, (2019); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Arnetz B. B., Ventimiglia M., Beech P., Demarinis V., Lokk J., Arnetz J. E., Spiritual values and practices in the workplace and employee stress and mental well-being, Journal of Management, Spirituality and Religion, 10, 3, pp. 271-281, (2013); Balog A. M., Baker L. T., Walker A. G., Religiosity and spirituality in entrepreneurship: A review and research agenda, Journal of Management, Spirituality and Religion, 11, 2, pp. 159-186, (2014); Bihari A., Tripathi S., Deepak A., A review on h-index and its alternative indices, Journal of Information Science, (2021); Bolton S. C., Being human: Dignity of labor as the foundation for the spirit-work connection, Journal of Management, Spirituality and Religion, 7, 2, pp. 157-172, (2010); Bright D. S., Fry R. E., Cooperrider D. L., Forgiveness from the perspectives of three response modes: Begrudgement, pragmatism, and transcendence, Journal of Management, Spirituality and Religion, 3, 1-2, pp. 78-103, (2006); Broadus R. N., Toward a definition of ""bibliometrics, Scientometrics, 12, 5-6, pp. 373-379, (1987); Brown R. B., Organizational spirituality: The sceptic's version, Organization, 10, 2, pp. 393-400, (2003); Callon M., Courtial J., Laville F., Co-word analysis as a tool for describing the network of interactions between basic and technological research: The case of polymer chemistry, Scientometrics, 22, 1, pp. 155-205, (1991); Chaston J., Lips-Wiersma M., When spirituality meets hierarchy: Leader spirituality as a double-edged sword, Journal of Management, Spirituality and Religion, 12, 2, pp. 111-128, (2015); Cobo M. J., Lopez-Herrera A. G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Collins D., Designing ethical organizations for spiritual growth and superior performance: An organization systems approach, Journal of Management, Spirituality and Religion, 7, 2, pp. 95-117, (2010); Driscoll C., McIsaac E. M., Wiebe E., The material nature of spirituality in the small business workplace: from transcendent ethical values to immanent ethical actions, Journal of Management, Spirituality and Religion, 16, 2, pp. 155-177, (2019); Driver M., A ""Spiritual Turn"" in organizational studies: Meaning making or meaningless?, Journal of Management, Spirituality & Religion, 4, 1, pp. 56-86, (2007); Exline J. J., Bright D. S., Spiritual and religious struggles in the workplace, Journal of Management, Spirituality and Religion, 8, 2, pp. 123-142, (2011); Fang H., Randolph R. V. D. G., Chrisman J. J., Barnett T., Firm religiosity, bounded stakeholder salience, and stakeholder relationships in family firms, Journal of Management, Spirituality and Religion, 10, 3, pp. 253-270, (2013); Fornaciari C. J., Lund Dean K., Foundations, lessons, and insider tips for MSR research, Journal of Management, Spirituality & Religion, 6, 4, pp. 301-321, (2009); Fry L W, Latham J. R., Clinebell S. K., Krahnke K., Spiritual leadership as a model for performance excellence: a study of Baldrige award recipients, Journal of Management, Spirituality and Religion, 14, 1, pp. 22-47, (2017); Fry Louis W, Matherly L. L., Ouimet J. -Rober, The Spiritual Leadership Balanced Scorecard Business Model: the case of the Cordon Bleu-Tomasso Corporation, Journal of Management, Spirituality & Religion, 7, 4, pp. 283-314, (2010); Geh E., Tan G., Spirituality at work in a changing world: Managerial and research implications, Journal of Management, Spirituality and Religion, 6, 4, pp. 287-300, (2009); Gingras Y., Bibliometrics and Research Evaluation: Uses and Abuses (History and Foundations of Information Science), (2016); Godwin J. L., Neck C. P., D'Intino R. S., Self-leadership, spirituality, and entrepreneur performance: a conceptual model, Journal of Management, Spirituality and Religion, 13, 1, pp. 64-78, (2016); Gotsis G., Kortezi Z., Philosophical foundations of workplace spirituality: A critical approach, Journal of Business Ethics, 78, 4, pp. 575-600, (2008); Guerrero-Bote V. P., Chinchilla-Rodriguez Z., Mendoza A., de Moya-Anegon F., Comparative Analysis of the Bibliographic Data Sources Dimensions and Scopus: An Approach at the Country and Institutional Levels, Frontiers in Research Metrics and Analytics, 5, pp. 1-12, (2021); Hirsch J. E., An index to quantify an individual's scientific research output, Proceedings of the National Academy of Sciences of the United States of America, 102, 46, pp. 16569-16572, (2005); Houghton J. D., Neck C. P., Krishnakumar S., The what, why, and how of spirituality in the workplace revisited: a 14-year update and extension, Journal of Management, Spirituality and Religion, 13, 3, pp. 177-205, (2016); Hunsaker W. D., Spiritual leadership and organizational citizenship behavior: relationship with Confucian values, Journal of Management, Spirituality and Religion, 13, 3, pp. 206-225, (2016); Jamali D., Sdiani Y., Does religiosity determine affinities to CSR?, Journal of Management, Spirituality and Religion, 10, 4, pp. 309-323, (2013); Jonsen R. H., Other-constituency theories and firm governance: is the benefit corporation sufficient?, Journal of Management, Spirituality and Religion, 13, 4, pp. 288-303, (2016); Kauanui S. K., Thomas K. D., Sherman C. L., Waters G. R., Gilea M., Exploring entrepreneurship through the lens of spirituality, Journal of Management, Spirituality and Religion, 5, 2, pp. 160-189, (2008); Kessler M. M., Bibliographic coupling between scientific papers, American documentation, 14, 1, pp. 10-25, (1963); Khari C., Sinha S., Transcendence at workplace scale: development and validation, Journal of Management, Spirituality and Religion, 17, 4, pp. 352-371, (2020); King J. E., Williamson I. O., Workplace religious expression, religiosity and job satisfaction: Clarifying a relationship, Journal of Management, Spirituality and Religion, 2, 2, pp. 173-198, (2005); Lee S., Lovelace K. J., Manz C. C., Serving with spirit: An integrative model of workplace spirituality within service organizations, Journal of Management, Spirituality and Religion, 11, 1, pp. 45-64, (2014); Low A., Purser R., Zen and the creative management of dilemmas, Journal of Management, Spirituality and Religion, 9, 4, pp. 335-355, (2012); Lu K., Wolfram D., Measuring author research relatedness: A comparison of word-based, topic-based, and author cocitation approaches, Journal of the American Society for Information Science and Technology, 63, 10, pp. 1973-1986, (2012); Madison K., Kellermanns F. W., Is the spiritual bond bound by blood? An exploratory study of spiritual leadership in family firms, Journal of Management, Spirituality and Religion, 10, 2, pp. 159-182, (2013); Martin-Martin A., Orduna-Malea E., Thelwall M., Delgado-Lopez-Cozar E., Google Scholar, Web of Science, and Scopus: Which is best for me? | Impact of Social Sciences, LSE Impact Blogs, pp. 1-4, (2019); Molloy K. A., Dik J., Davis D., Duffy ., Work calling and humility: framing for job idolization, workaholism, and exploitation, Journal of Management, Spirituality and Religion, 16, 5, pp. 428-444, (2019); Naimon E. C., Mullins M. E., Osatuke K., The effects of personality and spirituality on workplace incivility perceptions, Journal of Management, Spirituality and Religion, 10, 1, pp. 91-110, (2013); Petchsawang P., Duchon D., Workplace spirituality, meditation, and work performance, Journal of Management, Spirituality and Religion, 9, 2, pp. 189-208, (2012); Phipps K. A., The limitations of accommodation: the changing legal context of religion at work in the United States, Journal of Management, Spirituality and Religion, 16, 4, pp. 339-347, (2019); Pritchard A., Statistical bibliography or bibliometrics, Journal of documentation, 25, 4, pp. 348-249, (1969); Ritchie M., Nicholas D., Literature and bibliometrics, (1978); Saks A. M., Workplace spirituality and employee engagement, Journal of Management, Spirituality & Religion, 8, 4, pp. 317-340, (2011); Singh R. K., Singh S., Spirituality in the workplace: a systematic review, Management Decision, 60, 5, pp. 1296-1325, (2022); Tackney C. T., Chappell S., Harris D., Pavlovich K., Egel E., Major R., Finney M., Stoner J., Management, Spirituality, and Religion (MSR) ways and means: a paper to encourage quality research, Journal of Management, Spirituality and Religion, 14, 3, pp. 245-254, (2017); Van Den Dool E. C., The spirituality of Soelles liberation theology in social innovation: Empirical research into a via transformativa for organizations, Journal of Management, Spirituality and Religion, 9, 1, pp. 49-65, (2012); van Eck N. J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Van Noorden R., Google Scholar pioneer on search engine's future, Nature, pp. 1-3, (2020); Vu M. C., Gill R., Is there corporate mindfulness? An exploratory study of Buddhistenacted spiritual leaders' perspectives and practices, Journal of Management, Spirituality and Religion, 15, 2, pp. 155-177, (2018); Weitz E., Vardi Y., Setter O., Spirituality and organizational misbehavior, Journal of Management, Spirituality and Religion, 9, 3, pp. 255-281, (2012)","I.A.K. Maharani; Universitas Airlangga, Surabaya, Indonesia; email: ida.ayu.kartika.m-2020@feb.unair.ac.id","","International Association of Management, Spirituality and Religion","","","","","","14766086","","","","English","J. Manage. Spirit. Relig.","Article","Final","","Scopus","2-s2.0-85163816438" -"Huang H.; Chen Z.; Chen L.; Cao S.; Bai D.; Xiao Q.; Xiao M.; Zhao Q.","Huang, Huanhuan (57217985210); Chen, Zhiyu (57289255100); Chen, Lijuan (57959554200); Cao, Songmei (57217989184); Bai, Dingqun (36242990800); Xiao, Qian (36641303700); Xiao, Mingzhao (21643030200); Zhao, Qinghua (55509975300)","57217985210; 57289255100; 57959554200; 57217989184; 36242990800; 36641303700; 21643030200; 55509975300","Nutrition and sarcopenia: Current knowledge domain and emerging trends","2022","Frontiers in Medicine","9","","968814","","","","8","10.3389/fmed.2022.968814","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141614725&doi=10.3389%2ffmed.2022.968814&partnerID=40&md5=88642b2a7f3b285bbed3db1acf46e6d0","Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Department of Orthopedic, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Department of Nursing, The Affiliated Hospital of Jiangsu University, Jiangsu, Zhenjiang, China; Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Department of Geriatric, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China","Huang H., Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Chen Z., Department of Orthopedic, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Chen L., Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Cao S., Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Department of Nursing, The Affiliated Hospital of Jiangsu University, Jiangsu, Zhenjiang, China; Bai D., Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Xiao Q., Department of Geriatric, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Xiao M., Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Zhao Q., Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China","Objective: Non-pharmacological management like nutrient supplements has shown positive impacts on muscle mass and strength, which has burgeoned clinical and research interest internationally. The aim of this study was to analyze the current knowledge domain and emerging trends of nutrition-related research in sarcopenia and provide implications for future research and strategies to prevent or manage sarcopenia in the context of aging societies. Materials and methods: Nutrition- and sarcopenia-related research were obtained from the Web of Science Core Collection (WoSCC) database from its inception to April 1, 2022. Performance analysis, science mapping, and thematic clustering were performed by using the software VOSviewer and R package “bibliometrix.” Bibliometric analysis (BA) guideline was applied in this study. Results: A total of 8,110 publications were extracted and only 7,510 (92.60%) were selected for final analysis. The production trend in nutrition and sarcopenia research was promising, and 1,357 journals, 107 countries, 6,668 institutions, and 31,289 authors were identified in this field till 2021. Stable cooperation networks have formed in the field, but they are mostly divided by region and research topics. Health and sarcopenia, metabolism and nutrition, nutrition and exercise, body compositions, and physical performance were the main search themes. Conclusions: This study provides health providers and scholars mapped out a comprehensive basic knowledge structure in the research in the field of nutrition and sarcopenia over the past 30 years. This study could help them quickly grasp research hotspots and choose future research projects. Copyright © 2022 Huang, Chen, Chen, Cao, Bai, Xiao, Xiao and Zhao.","bibliometric analysis; co-words; nutrition; sarcopenia; VOSviewer","aging; Article; author; bibliometrics; body composition; clinical research; exercise; human; metabolism; nutrition; physical performance; prophylaxis; publication; sarcopenia; trend study; Web of Science","","","","","Chongqing Education Commission, (KJCX202 0018, yjg211006); Daqing Science and Technology Bureau, (CSTC2021jscx-gksb-N0021); Daqing Science and Technology Bureau","This research was funded by the Chongqing Science and Technology Bureau (CSTC2021jscx-gksb-N0021) and Chongqing Education Commission (yjg211006 and KJCX202 0018). ","World’s Older Population Grows Dramatically. 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Huang; Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; email: hxuehao@126.com; Q. Zhao; Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; email: qh20063@163.com","","Frontiers Media S.A.","","","","","","2296858X","","","","English","Front. Med.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85141614725" -"Forliano C.; De Bernardi P.; Yahiaoui D.","Forliano, Canio (57212088652); De Bernardi, Paola (57203532226); Yahiaoui, Dorra (55178208200)","57212088652; 57203532226; 55178208200","Entrepreneurial universities: A bibliometric analysis within the business and management domains","2021","Technological Forecasting and Social Change","165","","120522","","","","201","10.1016/j.techfore.2020.120522","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098453424&doi=10.1016%2fj.techfore.2020.120522&partnerID=40&md5=ad8a0007a8edcde06dd24cb3e1354133","University of Palermo, via Amico Ugo Antonio, Palermo, 90134, Italy; University of Turin, corso Unione Sovietica 218/bis, Turin, 10134, Italy; Kedge Business School, Domaine de Luminy, Rue Antoine Bourdelle, Marseille, 13009, France","Forliano C., University of Palermo, via Amico Ugo Antonio, Palermo, 90134, Italy, University of Turin, corso Unione Sovietica 218/bis, Turin, 10134, Italy; De Bernardi P., University of Turin, corso Unione Sovietica 218/bis, Turin, 10134, Italy; Yahiaoui D., Kedge Business School, Domaine de Luminy, Rue Antoine Bourdelle, Marseille, 13009, France","This study presents a bibliometric analysis of scientific publications investigating entrepreneurial universities in the business and management fields. The authors collected 511 documents from the Web of Science and analysed them using Bibliometrix, an RStudio package for performance analysis and science mapping. The study aims to provide an overview of the evolution of research about this topic and describe the structures (i.e., conceptual, social, and intellectual) characterising it. It discusses the results to identify the main areas addressed so far and highlight gaps in the literature, offering avenues for possible future research. The results show that publications on entrepreneurial universities started over 30 years ago and show an increasing trend, more than tripling in the last 10 years. Considering authors and documents as a unit of analysis, the US and Europe perform well in terms of productivity and relevance, but the phenomenon is globally relevant. The contribution to socio-economic development, especially in developing countries, is a hot topic for future studies. Despite increasing production rates, research on this topic remains fragmented, justifying the need for more systematisation. Furthermore, the paper offers policy makers and practitioners a useful baseline for developing entrepreneurial universities and considering their technological, managerial, and organisational implications. © 2020","Academic entrepreneurship; Bibliometric analysis; Bibliometrix; Entrepreneurial universities; Technology transfer","Developing countries; Bibliometric analysis; Business and management; Entrepreneurial university; Increasing production; Performance analysis; Scientific publications; Socio-economic development; Unit of analysis; academic performance; business development; entrepreneur; future prospect; technological development; technology transfer; university sector; Economics","","","","","","","Addor N., Melsen L.A., Legacy, rather than adequacy, drives the selection of hydrological models, Water Resour. 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Ventur., 21, 4, pp. 541-567, (2006); Waltman L., Van Eck N.J., A new methodology for constructing a publication-level classification system of science, J. Am. Soc. Inf. Sci. Technol., 63, 12, pp. 2378-2392, (2012); Wong P.K., Ho Y.P., Singh A., Towards an “entrepreneurial university” model to support knowledge-based economic development: the case of the National University of Singapore, World Dev, 35, 6, pp. 941-958, (2007)","C. Forliano; University of Palermo, via Amico Ugo Antonio, Palermo, 90134, Italy; email: canio.forliano@unito.it","","Elsevier Inc.","","","","","","00401625","","","","English","Technol. Forecast. Soc. Change","Article","Final","All Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-85098453424" -"Gupta A.; Mishra S.; Behera D.K.","Gupta, Anju (58917307000); Mishra, Shekhar (57208300973); Behera, Deepak Kumar (56959992500)","58917307000; 57208300973; 56959992500","Tracing the trajectory of financial vulnerability: a systematic review and bibliometric analysis","2024","Cogent Economics and Finance","12","1","2411566","","","","0","10.1080/23322039.2024.2411566","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85206273311&doi=10.1080%2f23322039.2024.2411566&partnerID=40&md5=8305177b7da737df1e2a22eb397a7b1b","Department of Commerce, Manipal Academy of Higher Education (MAHE), Manipal, India; Economics and Finance Department, The Business School, RMIT University, Ho Chi Minh City, Viet Nam","Gupta A., Department of Commerce, Manipal Academy of Higher Education (MAHE), Manipal, India; Mishra S., Department of Commerce, Manipal Academy of Higher Education (MAHE), Manipal, India; Behera D.K., Economics and Finance Department, The Business School, RMIT University, Ho Chi Minh City, Viet Nam","Over the span of 40 years, a substantial number of conceptual and empirical studies have been conducted on financial vulnerability (henceforth FV). These studies primarily covered socioeconomics, finance, management, and medicine. However, there is a paucity of comprehensive reviews and scientific mapping of the extant literature in the FV domain. Bibliometric analysis attempts to provide quantitative and qualitative knowledge in this area. This study was based on a review of 475 articles published in Scopus-indexed journals from 1990 to 2023. The present study employed the Biblioshiny R studio Bibliometrix package for data extraction and analysis. Our analysis provides information on recent publication trends; prominent authors, institutes, and countries; citations; thematic groups; keyword analysis; and social network analysis to identify influential work in this research domain and future gaps. The present analysis contributes to consolidating the existing fragmented literature on FV and highlights its significance during the current pandemic. Additionally, the study would be useful for researchers, practitioners, and academicians to proceed to further explore the area and outline the trends and their empirical investigation. © 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.","biblio-science mapping; bibliometric study; Computer Graphics & Visualization; Economics; Finance; Financial vulnerability; household financial vulnerability; systematic literature review","","","","","","","","Abdullah Yusof S., Abd Rokis R., Wan Jusoh W.J., Financial fragility of urban households in Malaysia, Jurnal Ekonomi Malaysia, 49, 1, pp. 15-24, (2015); Ali L., Khan M.K.N., Ahmad H., Financial fragility of Pakistani household, Journal of Family and Economic Issues, 41, 3, pp. 572-590, (2020); Al-Mamun A., Mazumder M.N.H., Impact of microcredit on income, poverty, and economic vulnerability in Peninsular Malaysia, Development in Practice, 25, 3, pp. 333-346, (2015); Altman E.I., Financial ratios, discriminant analysis, and the prediction of corporate bankruptcy, The Journal of Finance, 23, 4, pp. 589-609, (1968); Anderloni L., Bacchiocchi E., Vandone D., Household financial vulnerability: An empirical analysis, Research in Economics, 66, 3, pp. 284-296, (2012); Ando A., Modigliani F., The “life cycle” hypothesis of saving: aggregate implications and rests, American Economic Review, 53, 1, pp. 55-84, (1963); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Baker H.K., Pandey N., Kumar S., Haldar A., A bibliometric analysis of board diversity: Current status, development, and future research directions, Journal of Business Research, 108, pp. 232-246, (2020); Baker S.M., Gentry J.W., Rittenburg T.L., Building understanding of the domain of consumer vulnerability, Journal of Macromarketing, 25, 2, pp. 128-139, (2005); Bialowolski P., Weziak-Bialowolska D., The index of household financial condition, combining subjective and objective indicators: An appraisal of Italian households, Social Indicators Research, 118, 1, pp. 365-385, (2014); Blanco-Mesa F., Merigo J.M., Gil-Lafuente A.M., Fuzzy decision making: A bibliometric-based review, Journal of Intelligent & Fuzzy Systems, 32, 3, pp. 2033-2050, (2017); Borgy V., Bouthevillain C., Dufrenot G., Global imbalances and financial sector instabilities: Introduction, International Journal of Finance & Economics, 19, 1, pp. 1-2, (2014); Bowman W., Financial capacity and sustainability of ordinary nonprofits, Nonprofit Management and Leadership, 22, 1, pp. 37-51, (2011); Bridges S., Disney R., Use of credit and arrears on debt among low‐income families in the United Kingdom, Fiscal Studies, 25, 1, pp. 1-25, (2004); Brin S., Page L., The anatomy of a large-scale hypertextual web search engine, Computer Networks, 56, 18, pp. 3825-3833, (2012); Brown S., Taylor K., Household finances and the ‘Big Five’ personality traits, Journal of Economic Psychology, 45, pp. 197-212, (2014); Brunetti M., Giarda E., Torricelli C., Is financial fragility a matter of illiquidity? An appraisal for Italian households, Review of Income and Wealth, 62, 4, pp. 628-649, (2016); Burlamaqui L., Kregel J., Innovation, competition and financial vulnerability in economic development, Revista de Economia Política, 25, 2, pp. 5-22, (2005); Burton B., Kumar S., Pandey N., Twenty-five years of The European Journal of Finance (EJF): A retrospective analysis, The European Journal of Finance, 26, 18, pp. 1817-1841, (2020); Chapman K., Ellinger A.E., An evaluation of Web of Science, Scopus and Google Scholar citations in operations management, The International Journal of Logistics Management, 30, 4, pp. 1039-1053, (2019); Cho S., Hahm J.-H., Foreign currency noncore bank liabilities and macroprudential levy in Korea, Emerging Markets Finance and Trade, 50, 6, pp. 5-18, (2014); Chor D., Manova K., Off the cliff and back? 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Measures of scholarly esteem, Information Processing & Management, 47, 1, pp. 80-96, (2011); Ding Y., Chowdhury G.G., Foo S., Bibliometric cartography of information retrieval research by using co-word analysis, Information Processing & Management, 37, 6, pp. 817-842, (2001); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, 133, pp. 285-296, (2021); Duca M.L., Peltonen T.A., Assessing systemic risks and predicting systemic events, Journal of Banking & Finance, 37, 7, pp. 2183-2195, (2013); Dufrenot G., Gente K., Monsia F., Macroeconomic imbalances, financial stress and fiscal vulnerability in the euro area before the debt crises: A market view, Journal of International Money and Finance, 67, pp. 123-146, (2016); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, 3, pp. 1809-1831, (2015); Emmons W.R., Noeth B.J., Economic vulnerability and financial fragility, Review, 95, 5, pp. 361-388, (2013); Esfahani H., Tavasoli K., Jabbarzadeh A., Big data and social media: A scientometrics analysis, International Journal of Data and Network Science, 3, 3, pp. 145-164, (2019); Fernandes A.P., Ferreira P., Financing constraints and fixed-term employment: Evidence from the 2008-09 financial crisis, European Economic Review, 92, pp. 215-238, (2017); Fernandez-Lopez S., Alvarez-Espino M., Rey-Ares L., Castro-Gonzalez S., Consumer financial vulnerability: review, synthesis, and future research agenda, Journal of Economic Surveys, 38, 4, pp. 1045-1084, (2023); Friedman M., A theory of the consumption function, (1957); Gathergood J., Self-control, financial literacy and consumer over-indebtedness, Journal of Economic Psychology, 33, 3, pp. 590-602, (2012); Goyal K., Kumar S., Financial literacy: A systematic review and bibliometric analysis, International Journal of Consumer Studies, 45, 1, pp. 80-105, (2020); Greenlee J.S., Trussel J.M., Predicting the financial vulnerability of charitable organizations, Nonprofit Management and Leadership, 11, 2, pp. 199-210, (2000); Gupta A.S., Mukherjee J., Exploring personal savings versus hedonic consumption in the new normal, International Journal of Retail & Distribution Management, 52, 1, pp. 107-124, (2024); Gutter M.S., Saleem T., Financial vulnerability of small business owners, Financial Services Review, 14, 2, (2005); Hager M.A., Financial vulnerability among arts organizations: A test of the Tuckman-Chang measures, Nonprofit and Voluntary Sector Quarterly, 30, 2, pp. 376-392, (2001); Hahm J.-H., Shin H.S., Shin K., Noncore bank liabilities and financial vulnerability, Journal of Money, Credit and Banking, 45, s1, pp. 3-36, (2013); Haushofer J., Fehr E., On the psychology of poverty, Science, 344, 6186, pp. 862-867, (2014); Heidhues P., Koszegi B., Exploiting Naïvete about self-control in the credit market, American Economic Review, 100, 5, pp. 2279-2303, (2010); Hodge M.M., Piccolo R.F., Funding source, board involvement techniques, and financial vulnerability in nonprofit organizations: A test of resource dependence, Nonprofit Management and Leadership, 16, 2, pp. 171-190, (2005); Hoffmann A.O.I., McNair S.J., How does consumers’ financial vulnerability relate to positive and negative financial outcomes? The mediating role of individual psychological characteristics, Journal of Consumer Affairs, 53, 4, pp. 1630-1673, (2018); Ingale K.K., Paluri R.A., Financial literacy and financial behaviour: A bibliometric analysis, Review of Behavioral Finance, 14, 1, pp. 130-154, (2022); Jensenius F.R., Htun M., Samuels D.J., Singer D.A., Lawrence A., Chwe M., The benefits and pitfalls of Google Scholar, PS: Political Science & Politics, 51, 4, pp. 820-824, (2018); Kalil A., Mayer S., Shah R., Impact of the COVID-19 crisis on family dynamics in economically vulnerable households, (2020); Kim Y.I., Joo H.Y., Hyoung C.K., Household over-indebtedness and financial vulnerability in Korea: Evidence from credit bureau data, KDI Journal of Economic Policy, 38, 3, pp. 53-77, (2016); Kuek T.-H., Puah C.-H., Arip M.A., Financial vulnerability and economic dynamics in Malaysia, Journal of Central Banking Theory and Practice, 9, s1, pp. 55-73, (2020); Lachs M.S., Han S.D., Age-associated financial vulnerability: An emerging public health issue, Annals of Internal Medicine, 163, 11, pp. 877-878, (2015); Lambrecht B.M., The impact of debt financing on entry and exit in a duopoly, Review of Financial Studies, 14, 3, pp. 765-804, (2001); Leandro J.C., Botelho D., Consumer over-indebtedness: A review and future research agenda, Journal of Business Research, 145, pp. 535-551, (2022); Lee M.P., Sabri M.F., Review of financial vulnerability studies, Archives of Business Research, 5, 2, pp. 127-134, (2017); Lodge M., Hood C., Into an age of multiple austerities? Public management and public service bargains across OECD countries, Governance, 25, 1, pp. 79-101, (2011); Loke Y.J., Financial vulnerability of working adults in Malaysia, Contemporary Economics, 11, 2, pp. 205-218, (2017); Lusardi A., Mitchell O.S., Oggero N., Debt and financial vulnerability on the verge of retirement, Journal of Money, Credit and Banking, 52, 5, pp. 1005-1034, (2019); Magli A.S., Sabri M.F., Rahim H.A., The influence of financial attitude, financial behaviour, and self-belief towards financial vulnerability among public employees in Malaysia, Malaysian Journal of Consumer and Family Economics, 25, pp. 175-193, (2020); Mani A., Mullainathan S., Shafir E., Zhao J., Poverty impedes cognitive function, Science, 341, 6149, pp. 976-980, (2013); Manova K., Credit constraints, heterogeneous firms, and international trade, The Review of Economic Studies, 80, 2, pp. 711-744, (2012); Martin-Legendre J.I., Sanchez-Santos J.M., Household debt and financial vulnerability: empirical evidence for Spain, 2002–2020, Empirica, 51, 3, pp. 703-730, (2024); Mason K., Cornes M., Whiteford M., Dobson R., Ornelas B., Meakin A., Homeless people and adult social care in England: Exploring the challenges through researcher-practitioner partnership, Research, Policy and Planning, 33, 1, pp. 3-14, (2018); Midoes C., Sere M., Living with reduced income: An analysis of household financial vulnerability under COVID-19, Social Indicators Research, 161, 1, pp. 125-149, (2022); Modigliani F., Brumberg R., Utility analysis and the consumption function: An interpretation of cross-section data, Post-Keynesian Economics, 1, pp. 338-436, (1954); Mogaji E., Consumers’ financial vulnerability when accessing financial services, Research Agenda Working Papers, 2020, 3, pp. 27-39, (2020); Moral-Munoz J.A., Herrera-Viedma E., Santisteban-Espejo A., Cobo M.J., Software tools for conducting bibliometric analysis in science: An up-to-date review, Professional de la Información/Information Professional, 29, 1, (2020); Mukherjee D., Lim W.M., Kumar S., Donthu N., Guidelines for advancing theory and practice through bibliometric research, Journal of Business Research, 148, pp. 101-115, (2022); Noerhidajati S., Purwoko A.B., Werdaningtyas H., Kamil A.I., Dartanto T., Household financial vulnerability in Indonesia: Measurement and determinants, Economic Modelling, 96, pp. 433-444, (2021); O'Connor G.E., Newmeyer C.E., Wong N.Y.C., Bayuk J.B., Cook L.A., Komarova Y., Loibl C., Lin Ong L., Warmath D., Conceptualizing the multiple dimensions of consumer financial vulnerability, Journal of Business Research, 100, pp. 421-430, (2019); Orduna-Malea E., Martin Martin A., Delgado Lopez-Cozar E., Google Scholar as a source for scholarly evaluation: A bibliographic review of database errors, Revista española de Documentación Científica, 40, 4, (2017); Park D., Ramayandi A., Tian S., Debt buildup and currency vulnerability: Evidence from global markets, Emerging Markets Finance and Trade, 58, 7, pp. 2017-2035, (2022); Paul J., Lim W.M., O'Cass A., Hao A.W., Bresciani S., Scientific procedures and rationales for systematic literature reviews (SPAR‐4‐SLR), International Journal of Consumer Studies, 45, 4, pp. 1-16, (2021); Paxton K.C., Williams J.K., Bolden S., Guzman Y., Harawa N.T., HIV risk behaviors among African American women with at-risk male partners, Journal of AIDS & Clinical Research, 4, 7, (2013); Retirement needs and preferences of younger public workers, Issue Brief, (2017); Peretti-Watel P., Fressard L., Bocquier A., Verger P., Perceptions of cancer risk factors and socioeconomic status. 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Mishra; Department of Commerce, Manipal Academy of Higher Education (MAHE, Manipal, Karnataka, 576104, India; email: shekhar.mishra@manipal.edu","","Cogent OA","","","","","","23322039","","","","English","Cogent Econ. Finance","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85206273311" -"Orăștean R.; Mărginean S.C.","Orăștean, Ramona (39861906900); Mărginean, Silvia Cristina (39861906300)","39861906900; 39861906300","Renminbi Internationalization Process: A Quantitative Literature Review","2023","International Journal of Financial Studies","11","1","15","","","","5","10.3390/ijfs11010015","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85151071559&doi=10.3390%2fijfs11010015&partnerID=40&md5=185ba3384a0430ab701132b1501ebbdf","Faculty of Economic Sciences, Lucian Blaga University of Sibiu, Sibiu, 550324, Romania","Orăștean R., Faculty of Economic Sciences, Lucian Blaga University of Sibiu, Sibiu, 550324, Romania; Mărginean S.C., Faculty of Economic Sciences, Lucian Blaga University of Sibiu, Sibiu, 550324, Romania","As China’s position in the global economy has gradually improved, the importance of debates on the role of the renminbi in the international monetary system has significantly increased. This paper uses bibliometric methods—Bibliometrix R-package and its web-based graphical interface Biblioshiny—applied to data imported from Web of Science and Scopus to investigate and synthesize the renminbi literature published in English between 1995 and 2021. Science mapping offers a visual representation of different networks and clusters of authors’ keywords. The performance analysis, a quantitative evaluation of the most published sources, authors and papers on renminbi internationalization in the last 25 years, shows that the interest on the topic has grown, particularly after 2009 and 2016, respectively. There is also a high degree of concentration in the field, considering that out of the 802 analyzed papers, published in 393 sources, five authors and four journals had the highest impact. The content analysis identifies the main directions in the renminbi internationalization literature and future research questions to further explore this subject. The COVID-19 pandemic and post-Ukraine war era could generate a deeper reform of the international monetary system, in which the Chinese currency will strengthen its global position alongside the US dollar and the euro. © 2023 by the authors.","bibliometric analysis; Bibliometrix; Biblioshiny; Chinese currency; renminbi internationalization; science mapping","","","","","","","","Ahmed S., Alshater M.M., El Ammari A., Hammami H., Artificial intelligence and machine learning in finance: A bibliometric review, Research in International Business and Finance, 61, (2022); Alshater M.M., Atayah O.F., Khan A., What do we know about business and economics research during COVID-19: A bibliometric review, Economic Research-Ekonomska Istraživanja, 35, pp. 1884-1912, (2022); Aria M., Cuccurullo C., Bibliometrix: An R-tool for Comprehensive Science Mapping Analysis, Journal of Informetrics, 11, pp. 959-975, (2017); Aria M., Misuraca M., Spano M., Mapping the Evolution of Social Research and Data Science on 30 Years of Social Indicators Research, Social Indicators Research, 149, pp. 803-831, (2020); Balz B., The Role of the Renminbi in International Payments, Proceedings of the 5th European-Chinese Banking Day as part of the Euro Finance Week, (2018); Bamel U., Pereira V., Del Giudice M., Temouri Y., The extent and impact of intellectual capital research: A two decade analysis, Journal of Intellectual Capital, 23, pp. 375-400, (2020); Benassy-Quere A., Forouheshfar Y., The Impact of Yuan Internationalization on the Euro-Dollar Exchange Rate, (2013); Benassy-Quere A., Forouheshfar Y., The impact of yuan internationalization on the stability of the international monetary system, Journal of International Money and Finance, 57, pp. 115-135, (2015); Benassy-Quere A., Sophie B., Valerie M., On the Complementarity of Equilibrium Exchange-Rate Approaches, Review of International Economics, 18, pp. 618-632, (2010); Bibliometrix R-Package, (2020); (2019); Cao M., Alon I., Intellectual Structure of the Belt and Road Initiative Research: A Scientometric Analysis and Suggestions for a Future Research Agenda, Sustainability, 12, (2020); The BRI and the London Market—The Next Steps in Renminbi Internationalization, (2017); Chen H., Peng W., The Potential of the Renminbi as an International Currency, Currency Internationalization: Global Experiences and Implications for the Renminbi, (2010); Cheung Y.-W., de Haan J., Qian X., Yu S., China’s Outward Direct Investment in Africa, Review of International Economics, 20, pp. 201-220, (2012); Cheung Y.-W., Chinn M.D., Fujii E., The overvaluation of Renminbi undervaluation, Journal of International Money and Finance, 26, pp. 762-785, (2007); Cheung Y.-W., Chinn M.D., Fujii E., Pitfalls in measuring exchange rate misalignment: The Yuan and other currencies, Open Economies Review, 20, pp. 183-206, (2009); Chinn M., A Note on Reserve Currencies with Special Reference to the G-20 Countries, (2012); Chorzempa M., China, the United States, and Central Bank Digital Currencies: How Important is it to be First?, China Economic Journal, 14, pp. 102-115, (2021); News Center, (2021); Cuccurullo C., Aria M., Sarto F., Foundations and Trends in Performance Management. 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Orăștean; Faculty of Economic Sciences, Lucian Blaga University of Sibiu, Sibiu, 550324, Romania; email: ramona.orastean@ulbsibiu.ro","","MDPI","","","","","","22277072","","","","English","Intern. J. Financial Stud.","Review","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85151071559" -"Kussainova R.E.; Urazbayeva G.T.; Kaliyeva A.B.; Denst-Garcia E.","Kussainova, Raisa Esenovna (57216705621); Urazbayeva, Gulsara Tundebayevna (58697506900); Kaliyeva, Assel Bolatovna (57497200600); Denst-Garcia, Edyta (58697795700)","57216705621; 58697506900; 57497200600; 58697795700","Innovative Teaching: A Bibliometric Analysis From 2013 to 2023","2023","European Journal of Educational Research","13","1","","233","247","14","4","10.12973/eu-jer.13.1.233","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175576073&doi=10.12973%2feu-jer.13.1.233&partnerID=40&md5=3a54602f8f7905f05d66bb14270733e2","L.N. Gumilyov Eurasian National University, Kazakhstan; Nazarbayev University, Kazakhstan","Kussainova R.E., L.N. Gumilyov Eurasian National University, Kazakhstan; Urazbayeva G.T., L.N. Gumilyov Eurasian National University, Kazakhstan; Kaliyeva A.B., L.N. Gumilyov Eurasian National University, Kazakhstan; Denst-Garcia E., Nazarbayev University, Kazakhstan","This study sought to investigate the current state of innovative teaching research and identify emerging themes and trends in the field from 2013 to 2023. The Scopus database was searched for the term “innovative teaching,” resulting in 1005 documents. After manual screening, 903 articles were exported in the BibTeX format for further processing in Bibliometrix using three bibliometric analysis types: network analysis, science mapping, and performance analysis. Performance analysis revealed bursts in publication output in 2015 and 2021, with a moderate boost in 2018. Ten top-cited journal papers were identified. The citation rates were low between 2019 and 2021, but there has been an upturn since 2022. The top keywords included simulation and nursing education, and there was a shift in research topics from broad educational concepts to more specific approaches, such as e-learning. Innovative teaching has been predominantly investigated in higher education, particularly in nursing education, with themes like “teaching/learning strategies” suggesting an emphasis on enhancing teaching practices not just through technology infusion. This study can aid educators and researchers in staying current with innovative teaching developments and inform their teaching practices. © 2024 The Author(s).","Bibliometrics; Bibliometrix; innovative teaching; research trends; topic evolution","","","","","","","","Abdullah M. 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K., The journal Buildings: A bibliometric analysis (2011–2021), Buildings, 12, 1, (2022); Yamaguchi Y., Ryuno H., Fukuda A., Kabaya S., Isowa T., Hiramatsu M., Kitagawa A., Hattori Y., Williamson A., Greiner C., Effects of a virtual reality intervention on dementia care education among acute care nurses in Japan: A non-randomised controlled trial, Geriatric Nursing, 48, pp. 269-273, (2022); Yu Y., Jin Z., Qiu J., Global isotopic hydrograph separation research history and trends: A text mining and bibliometric analysis study, Water, 13, 18, (2021); Zarestky J., Bigler M., Brazile M., Lopes T., Bangerth W., Reflective writing supports metacognition and self-regulation in graduate computational science and engineering, Computers and Education Open, 3, (2022); Zhang L., Carter R. A., Qian X., Yang S., Rujimora J., Wen S., Academia’s responses to crisis: A bibliometric analysis of literature on online learning in higher education during COVID‐19, British Journal of Educational Technology, 53, 3, pp. 620-646, (2022); Zhang Y., Wang P., Twenty years’ development of teacher identity research: A bibliometric analysis, Frontiers in Psychology, 12, (2021)","G.T. Urazbayeva; L. N. Gumilyov Eurasian National University, Kazakhstan; email: gsrzb@aol.com","","Eurasian Society of Educational Research","","","","","","21658714","","","","English","European J Educ. Res.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85175576073" -"Aria M.; Cuccurullo C.","Aria, Massimo (23388148900); Cuccurullo, Corrado (36489082700)","23388148900; 36489082700","bibliometrix: An R-tool for comprehensive science mapping analysis","2017","Journal of Informetrics","11","4","","959","975","16","8398","10.1016/j.joi.2017.08.007","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029313621&doi=10.1016%2fj.joi.2017.08.007&partnerID=40&md5=277ba69eb32d964445d4db7ad9388954","Department of Economics and Statistics, Università degli Studi di Napoli Federico II, Via Cintia, C.sso M.te S.Angelo, Naples, 80126, Italy; Department of Economics and Management, Università della Campania Luigi Vanvitelli, Corso Gran Priorato di Malta, Capua, CE, Italy","Aria M., Department of Economics and Statistics, Università degli Studi di Napoli Federico II, Via Cintia, C.sso M.te S.Angelo, Naples, 80126, Italy; Cuccurullo C., Department of Economics and Management, Università della Campania Luigi Vanvitelli, Corso Gran Priorato di Malta, Capua, CE, Italy","The use of bibliometrics is gradually extending to all disciplines. It is particularly suitable for science mapping at a time when the emphasis on empirical contributions is producing voluminous, fragmented, and controversial research streams. Science mapping is complex and unwieldly because it is multi-step and frequently requires numerous and diverse software tools, which are not all necessarily freeware. Although automated workflows that integrate these software tools into an organized data flow are emerging, in this paper we propose a unique open-source tool, designed by the authors, called bibliometrix, for performing comprehensive science mapping analysis. bibliometrix supports a recommended workflow to perform bibliometric analyses. As it is programmed in R, the proposed tool is flexible and can be rapidly upgraded and integrated with other statistical R-packages. It is therefore useful in a constantly changing science such as bibliometrics. © 2017 Elsevier Ltd","Bibliographic coupling; Bibliometrics; Co-citation; R package; Science mapping; Workflow","Computer software; Data flow analysis; Open source software; Open systems; Bibliographic couplings; Bibliometric analysis; Bibliometrics; Cocitation; Mapping analysis; Open source tools; Work-flows; Workflow; Mapping","","","","","","","Alavifard S., hindexcalculator: H-index calculator using data from a web of science (WoS) citation report. R package version 1.0.0, (2015); Borner K., Chen C., Boyack K.W., Visualizing knowledge domains, Annual Review of Information Science and Technology, 37, 1, pp. 179-255, (2003); Bailon-Moreno R., Jurado-Alameda E., Ruiz-Banos R., The scientific network of surfactants: Structural analysis, Journal of the American Society for Information Science and Technology, 57, 7, pp. 949-960, (2006); Bar-Ilan J., Which h-index? 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An analysis of some well-known similarity measures, Journal of the Association for Information Science and Technology, 60, 8, pp. 1635-1651, (2009); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); van Eck N.J., Waltman L., CitNetExplorer: A new software tool for analyzing and visualizing citation networks, Journal of Informetrics, 8, 4, pp. 802-823, (2014); van Eck N.J., Waltman L., Noyons C.M., A unified approach to mapping and clustering of bibliometric networks14, Eleventh International Conference on Science and Technology Indicators, (2010)","M. Aria; Department of Economics and Statistics, Università degli Studi di Napoli Federico II, Naples, Via Cintia, C.sso M.te S.Angelo, 80126, Italy; email: aria@unina.it","","Elsevier Ltd","","","","","","17511577","","","","English","J. Inf.","Article","Final","","Scopus","2-s2.0-85029313621" -"Mao Y.; Fu Q.; Su F.; Zhang W.; Zhang Z.; Zhou Y.; Yang C.","Mao, Yukang (57223043084); Fu, Qiangqiang (55040590100); Su, Feng (56428480900); Zhang, Wenjia (59353493100); Zhang, Zhong (58318019200); Zhou, Yimeng (58318674400); Yang, Chuanxi (57201460531)","57223043084; 55040590100; 56428480900; 59353493100; 58318019200; 58318674400; 57201460531","Trends in worldwide research on cardiac fibrosis over the period 1989–2022: a bibliometric study","2023","Frontiers in Cardiovascular Medicine","10","","1182606","","","","5","10.3389/fcvm.2023.1182606","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85162207495&doi=10.3389%2ffcvm.2023.1182606&partnerID=40&md5=70c28314010cb67f8e065a8da8982429","Department of Cardiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Department of General Practice, Clinical Research Center for General Practice, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China; Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China","Mao Y., Department of Cardiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Fu Q., Department of General Practice, Clinical Research Center for General Practice, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China; Su F., Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China; Zhang W., Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China; Zhang Z., Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China; Zhou Y., Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China; Yang C., Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China","Background: Cardiac fibrosis is a hallmark of various end-stage cardiovascular diseases (CVDs) and a potent contributor to adverse cardiovascular events. During the past decades, extensive publications on this topic have emerged worldwide, while a bibliometric analysis of the current status and research trends is still lacking. Methods: We retrieved relevant 13,446 articles on cardiac fibrosis published between 1989 and 2022 from the Web of Science Core Collection (WoSCC). Bibliometrix was used for science mapping of the literature, while VOSviewer and CiteSpace were applied to visualize co-authorship, co-citation, co-occurrence, and bibliographic coupling networks. Results: We identified four major research trends: (1) pathophysiological mechanisms; (2) treatment strategies; (3) cardiac fibrosis and related CVDs; (4) early diagnostic methods. The most recent and important research themes such as left ventricular dysfunction, transgenic mice, and matrix metalloproteinase were generated by burst analysis of keywords. The reference with the most citations was a contemporary review summarizing the role of cardiac fibroblasts and fibrogenic molecules in promoting fibrogenesis following myocardial injury. The top 3 most influential countries were the United States, China, and Germany, while the most cited institution was Shanghai Jiao Tong University, followed by Nanjing Medical University and Capital Medical University. Conclusions: The number and impact of global publications on cardiac fibrosis has expanded rapidly over the past 30 years. These results are in favor of paving the way for future research on the pathogenesis, diagnosis, and treatment of cardiac fibrosis. 2023 Mao, Fu, Su, Zhang, Zhang, Zhou and Yang.","bibliometric; cardiac fibrosis; citespace; research trend; systematic review; VOSviewer","losartan; matrix metalloproteinase; microRNA; mitogen activated protein kinase 1; aortic stenosis; Article; atrial fibrillation; bibliometrics; cardiorenal syndrome; cardiovascular disease; China; diabetic cardiomyopathy; diastolic dysfunction; echocardiography; fibroblast; fibrogenesis; Germany; heart amyloidosis; heart failure with preserved ejection fraction; heart muscle fibrosis; human; hypertrophic cardiomyopathy; Japan; medical research; myofibroblast; nonhuman; oxidative stress; trend study; United States","","losartan, 114798-26-4; mitogen activated protein kinase 1, 137632-08-7","","","National Natural Science Foundation of China, NSFC, (82200379); National Natural Science Foundation of China, NSFC","This work was funded by the Youth Program of National Natural Science Foundation of China (82200379). 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Cenko E., Badimon L., Bugiardini R., Claeys M.J., De Luca G., de Wit C., Et al., Cardiovascular disease and COVID-19: a consensus paper from the ESC working group on coronary pathophysiology & microcirculation, ESC working group on thrombosis and the association for acute CardioVascular care (ACVC), in collaboration with the European heart rhythm association (EHRA), Cardiovasc Res, 117, pp. 2705-2729, (2021); Vestri A., Pierucci F., Frati A., Monaco L., Meacci E., Sphingosine 1-phosphate receptors: do they have a therapeutic potential in cardiac fibrosis?, Front Pharmacol, 8, (2017); Liu T., Song D., Dong J., Zhu P., Liu J., Liu W., Et al., Current understanding of the pathophysiology of myocardial fibrosis and its quantitative assessment in heart failure, Front Physiol, 8, (2017); Tuleta I., Frangogiannis N.G., Fibrosis of the diabetic heart: clinical significance, molecular mechanisms, and therapeutic opportunities, Adv Drug Delivery Rev, 176, (2021); van der Bijl P., Podlesnikar T., Bax J.J., Delgado V., Sudden cardiac death risk prediction: the role of cardiac magnetic resonance imaging, Rev Esp Cardiol, 71, pp. 961-970, (2018); Maruyama K., Imanaka-Yoshida K., The pathogenesis of cardiac fibrosis: a review of recent progress, Int J Mol Sci, 23, (2022); Alenazy A., Eltayeb A., Alotaibi M.K., Anwar M.K., Mulafikh N., Aladmawi M., Et al., Diagnosis of mitral valve prolapse: much more than simple prolapse. Multimodality approach to risk stratification and therapeutic management, J Clin Med, 11, (2022); Morfino P., Aimo A., Castiglione V., Galvez-Monton C., Emdin M., Bayes-Genis A., Treatment of cardiac fibrosis: from neuro-hormonal inhibitors to CAR-T cell therapy, Heart Fail Rev, 28, 2, pp. 1-15, (2022); Zhang Q., Wang L., Wang S., Cheng H., Xu L., Pei G., Et al., Signaling pathways and targeted therapy for myocardial infarction, Signal Transduct Target Ther, 7, (2022); Raziyeva K., Kim Y., Zharkinbekov Z., Temirkhanova K., Saparov A., Novel therapies for the treatment of cardiac fibrosis following myocardial infarction, Biomedicines, 10, (2022); Su M., Cui J., Zhao J., Fu X., Skimmin ameliorates cardiac function via the regulation of M2 macrophages in a myocardial infarction mouse model, Perfusion, (2022); Liu Y., Hu J., Wang W., Wang Q., MircroRNA-145 attenuates cardiac fibrosis via regulating mitogen-activated protein kinase kinase kinase 3, Cardiovasc Drugs Ther, (2022); Meng T., Wang P., Ding J., Du R., Gao J., Li A., Et al., Global research trends on ventricular remodeling: a bibliometric analysis from 2012 to 2022, Curr Probl Cardiol, 47, (2022); Ebrahim N., Al Saihati H.A., Mostafa O., Hassouna A., Abdulsamea S., Abd El Aziz M El Gebaly E., Et al., Prophylactic evidence of MSCs-derived exosomes in doxorubicin/trastuzumab-induced cardiotoxicity: beyond mechanistic target of NRG-1/erb signaling pathway, Int J Mol Sci, 23, (2022); Travers J.G., Kamal F.A., Robbins J., Yutzey K.E., Blaxall B.C., Cardiac fibrosis: the fibroblast awakens, Circ Res, 118, pp. 1021-1040, (2016); Ponikowski P., Voors A.A., Anker S.D., Bueno H., Cleland J.G.F., Coats A.J.S., Et al., 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European society of cardiology (ESC)Developed with the special contribution of the heart failure association (HFA) of the ESC, Eur Heart J, 37, pp. 2129-2200, (2016); Kong P., Christia P., Frangogiannis N.G., The pathogenesis of cardiac fibrosis, Cell Mol Life Sci, 71, pp. 549-574, (2014); Khalil H., Kanisicak O., Prasad V., Correll R.N., Fu X., Schips T., Et al., Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac fibrosis, J Clin Invest, 127, pp. 3770-3783, (2017); Frangogiannis N.G., Cardiac fibrosis: cell biological mechanisms, molecular pathways and therapeutic opportunities, Mol Aspects Med, 65, pp. 70-99, (2019); Flett A.S., Hayward M.P., Ashworth M.T., Hansen M.S., Taylor A.M., Elliott P.M., Et al., Equilibrium contrast cardiovascular magnetic resonance for the measurement of diffuse myocardial fibrosis: preliminary validation in humans, Circulation, 122, pp. 138-144, (2010); Moon J.C., Messroghli D.R., Kellman P., Piechnik S.K., Robson M.D., Ugander M., Et al., Myocardial T1 mapping and extracellular volume quantification: a society for cardiovascular magnetic resonance (SCMR) and CMR working group of the European society of cardiology consensus statement, J Cardiovasc Magn Reson, 15, (2013); Lang R.M., Badano L.P., Mor-Avi V., Afilalo J., Armstrong A., Ernande L., Et al., Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American society of echocardiography and the European association of cardiovascular imaging, Eur Heart J Cardiovasc Imaging, 16, pp. 233-270, (2015); Mewton N., Liu C.Y., Croisille P., Bluemke D., Lima J.A., Assessment of myocardial fibrosis with cardiovascular magnetic resonance, J Am Coll Cardiol, 57, pp. 891-903, (2011); Zinman B., Wanner C., Lachin J.M., Fitchett D., Bluhmki E., Hantel S., Et al., Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes, N Engl J Med, 373, pp. 2117-2128, (2015); Kessler M.M., Bibliographic coupling between scientific papers, Am Doc, 14, pp. 10-25, (1963); Crawford D.C., Chobanian A.V., Brecher P., Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat, Circ Res, 74, pp. 727-739, (1994); Robert V., Heymes C., Silvestre J.S., Sabri A., Swynghedauw B., Delcayre C., Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: role in aldosterone-salt-induced fibrosis, Hypertension, 33, pp. 981-986, (1999); Hou J., Kato H., Cohen R.A., Chobanian A.V., Brecher P., Angiotensin II-induced cardiac fibrosis in the rat is increased by chronic inhibition of nitric oxide synthase, J Clin Invest, 96, pp. 2469-2477, (1995); Ju H., Zhao S., Jassal D.S., Dixon I.M., Effect of AT1 receptor blockade on cardiac collagen remodeling after myocardial infarction, Cardiovasc Res, 35, pp. 223-232, (1997); Yang F., Yang X.P., Liu Y.H., Xu J., Cingolani O., Rhaleb N.E., Et al., Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction, Hypertension, 43, pp. 229-236, (2004); Brouri F., Hanoun N., Mediani O., Saurini F., Hamon M., Vanhoutte P.M., Et al., Blockade of beta 1- and desensitization of beta 2-adrenoceptors reduce isoprenaline-induced cardiac fibrosis, Eur J Pharmacol, 485, pp. 227-234, (2004); Teekakirikul P., Eminaga S., Toka O., Alcalai R., Wang L., Wakimoto H., Et al., Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires tgf-β, J Clin Invest, 120, pp. 3520-3529, (2010); Pucci A., Aimo A., Musetti V., Barison A., Vergaro G., Genovesi D., Et al., Amyloid deposits and fibrosis on left ventricular endomyocardial biopsy correlate with extracellular volume in cardiac amyloidosis, J Am Heart Assoc, 10, (2021); Sygitowicz G., Maciejak-Jastrzebska A., Sitkiewicz D., The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases, Biomolecules, 12, (2021); Greenberg S.A., How citation distortions create unfounded authority: analysis of a citation network, Br Med J, 339, (2009)","Y. Zhou; Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China; email: zhouyimeng@medmail.com.cn; C. Yang; Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China; email: 2205515@tongji.edu.cn","","Frontiers Media S.A.","","","","","","2297055X","","","","English","Front. Cardiovasc. Med.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85162207495" -"John A.; Firoz C M.","John, Ashna (57946045200); Firoz C, Mohammed (57208471201)","57946045200; 57208471201","COMPETITIVENESS OF TOURISM DESTINATIONS: A MIXED-METHOD BIBLIOMETRIC APPROACH","2022","Enlightening Tourism","12","2","","691","731","40","2","10.33776/et.v12i2.6820","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140851553&doi=10.33776%2fet.v12i2.6820&partnerID=40&md5=c4497e65e8dc23992b95b4905a08baf0","National Institute of Technology, Calicut, India","John A., National Institute of Technology, Calicut, India; Firoz C M., National Institute of Technology, Calicut, India","Even after almost three decades of introducing competitiveness into the tourism sector, there is still a rising trend in literature on Tourism Destination Competitiveness (TDC). Though there are a few systematic and traditional reviews in the domain, there has been no study of the bibliometric variables. In the current study, scientific literature on the topic is mapped through evaluative and relational bibliometric techniques utilizing Web of Science (161 documents) and Scopus (manually selected five documents) databases to run a bibliometric analysis of 166 documents on TDC, uncovering the domain's research trend concerning authors, sources, and publications. The science mapping tool bibliometrix R-package biblioshiny and VOSviewer are used to analyze the trend of scientific publications in the area, untapped knowledge, possible future trends, and implications. The analysis is undertaken on three levels: source, author, and document, as well as three types of knowledge structures: conceptual, intellectual, and social. The bibliometric analysis consists of a descriptive evaluation of the bibliographic data frame, network analyses, and graphical visualization. As per the analysis, the competitiveness of natural/cultural destinations is rarely assessed in the global scenario. The maximum number of studies in the domain are carried out in European countries. The findings can guide researchers to focus on less developed themes/areas. © 2022, Universidad de Huelva. All rights reserved.","Bibliometric analysis; Bibliometrix; Biblioshiny; Destination competitiveness; TDC; Tourism; VOSviewer","","","","","","","","Abreu-Novais M., Ruhanen L, Arcodia C., Destination competitiveness: what we know, what we know but shouldn't and what we don't know but should, Current Issues in Tourism, 19, 6, pp. 492-512, (2016); Abreu-Novais M., Ruhanen L., Arcodia C., Destination competitiveness: A phenomenographic study, Tourism Management, 64, pp. 324-334, (2018); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Benckendorff P., Zehrer A., A network analysis of tourism research, Annals of Tourism Research, 43, pp. 121-149, (2013); Borner K., Chen C., Boyack K.W., Visualizing knowledge domains, Annual Review of Information Science & Technology, 37, 1, pp. 179-255, (2005); Buhalis D., Marketing the competitive destination of the future, Tourism Management, 21, 1, pp. 97-116, (2000); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Cracolici M.F., Nijkamp P., The attractiveness and competitiveness of tourist destinations: A study of Southern Italian regions, Tourism Management, 30, 3, pp. 336-344, (2009); Cronje D.F., du Plessis E., A review on tourism destination competitiveness, Journal of Hospitality and Tourism Management, 45, pp. 256-265, (2020); Cronjea D., du Plessis E., What makes South Africa competitive from a tourist's point of view?, Development Southern Africa, 38, 6, pp. 919-937, (2020); Crouch G.I., Ritchie J.R.B., Tourism, Competitiveness, and Societal Prosperity, Journal of Business Research, 44, 3, pp. 137-152, (1999); Cuccurullo C., Aria M., Sarto F., Foundations and trends in performance management. A twenty-five years bibliometric analysis in business and public administration domains, Scientometrics, 108, 2, pp. 595-611, (2016); Dominguez Vila T., Darcy S., Alen Gonzalez E., Competing for the disability tourism market – A comparative exploration of the factors of accessible tourism competitiveness in Spain and Australia, Tourism Management, 47, pp. 261-272, (2015); Dwyer L., Kim C., Destination Competitiveness: Determinants and Indicators, Current Issues in Tourism, 6, 5, pp. 369-414, (2003); Elango B., Rajendran P., Authorship trends and collaboration pattern in the marine sciences literature: a scientometric study, International Journal of Information Dissemination and Technology, 2, 3, pp. 166-169, (2012); Enright M.J., Newton J., Tourism Destination Competitiveness: A Quantitative Approach, Tourism Management, 25, 6, pp. 777-788, (2004); Firdaus A., Razak M.F.A., Feizollah A., Hashem I.A.T., Hazim M., Anuar N.B., The rise of ""blockchain"": bibliometric analysis of blockchain study, Scientometrics, 120, 3, pp. 1289-1331, (2019); Goffi G., A Model of Tourism Destination Competitiveness: The case of the Italian Destinations of Excellence, Anuario Turismo y Sociedad, 14, pp. 121-147, (2013); Gomezelj D.O., Mihalic T., Destination competitiveness-Applying different models, the case of Slovenia, Tourism Management, 29, 2, pp. 294-307, (2008); Hassan S.S., Determinants of Market Competitiveness in an Environmentally Sustainable Tourism Industry, Journal of Travel Research, 38, 3, pp. 239-245, (2000); Koseoglu M.A., Rahimi R., Okumus F., Liu J., Bibliometric studies in tourism, Annals of Tourism Research, 61, pp. 180-198, (2016); Kozak M., Measuring comparative performance of vacation destinations: Using tourists' self-reported judgments as an alternative approach, Tourism Analysis, 8, 2–4, pp. 247-251, (2003); Kubickova M., The impact of government policies on destination competitiveness in developing economies, Current Issues in Tourism, 22, 6, pp. 619-642, (2019); Kubickova M., Li H., Tourism Competitiveness, Government and Tourism Area Life Cycle (TALC) Model: The Evaluation of Costa Rica, Guatemala and Honduras, International Journal of Tourism Research, 19, 2, pp. 223-234, (2017); Kubickova M., Martin D., Exploring the relationship between government and destination competitiveness: The TALC model perspective, Tourism Management, 78, (2020); Leung X.Y., Baloglu S., Tourism Competitiveness of Asia Pacific Destinations, Tourism Analysis, 18, 4, pp. 371-384, (2013); Mongeon P., Paul-Hus A., The journal coverage of Web of Science and Scopus: a comparative analysis, Scientometrics, 106, 1, pp. 213-228, (2016); Poon A., Tourism, Technology and Competitive Strategies, (1993); Porter M.E., The Competitive Advantage of Nations, Harvard Business Review, 68, 2, pp. 73-93, (1990); Porter M.E., Industry Structure and Competitive Strategy: Keys to Profitability, Financial Analysts Journal, 36, 4, pp. 30-41, (1980); Ritchie J.R.B., Crouch G.I., The Competitive Destination: A Sustainable Tourism Perspective, (2003); Rodriguez-Lopez N., Dieguez-Castrillon M.I., Gueimonde-Canto A., Sustainability and Tourism Competitiveness in Protected Areas: State of Art and Future Lines of Research, Sustainability, 11, 22, (2019); Roman M., Roman M., Prus P., Szczepanek M., Tourism Competitiveness of Rural Areas: Evidence from a Region in Poland, Agriculture, 10, 11, (2020); Segui-Amortegui L., Clemente-Almendros J.A., Medina R., Grueso Gala M., Sustainability and Competitiveness in the Tourism Industry and Tourist Destinations: A Bibliometric Study, Sustainability, 11, 22, (2019); Small H., Co-citation in the scientific literature: A new measure of the relationship between two documents, Journal of the American Society for Information Science, 24, 4, pp. 265-269, (1973); Teixeira S.J., Ferreira J.J.D.M., A bibliometric study of regional competitiveness and tourism innovation, International Journal of Tourism Policy, 8, 3, pp. 214-243, (2018); Zhang J., Yu Q., Zheng F., Long C., Lu Z., Duan Z., Comparing keywords plus of WOS and author keywords: A case study of patient adherence research, Journal of 730 the Association for Information Science and Technology, 67, 4, pp. 967-972, (2016); Zupic I., Cater T., Bibliometric Methods in Management and Organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","","","Universidad de Huelva","","","","","","2174548X","","","","English","Enlight. Tour.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85140851553" -"Padhan L.; Bhat S.","Padhan, Lakshmana (57799298000); Bhat, Savita (26029735500)","57799298000; 26029735500","Interrelationship between trade and environment: a bibliometric analysis of published articles from the last two decades","2023","Environmental Science and Pollution Research","30","7","","17051","17075","24","8","10.1007/s11356-023-25168-5","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85145908792&doi=10.1007%2fs11356-023-25168-5&partnerID=40&md5=571f847d0bb3aff49436cd487ad0d0ed","School of Humanities, Social Sciences and Management, National Institute of Technology Karnataka, NH 66, Srinivas Nagar, Surathkal, Karnataka, Mangalore, -575025, India","Padhan L., School of Humanities, Social Sciences and Management, National Institute of Technology Karnataka, NH 66, Srinivas Nagar, Surathkal, Karnataka, Mangalore, -575025, India; Bhat S., School of Humanities, Social Sciences and Management, National Institute of Technology Karnataka, NH 66, Srinivas Nagar, Surathkal, Karnataka, Mangalore, -575025, India","Extant literature indicates that the concepts of international trade and the environment are intertwined. There is a plethora of theoretical and empirical research studies that explore the relationship between the two concepts. However, no bibliometric attempts have been made to analyze these publications to understand the current research trends in the trade and environment regulation/protection/policy intersection. Hence, the present study conducted a bibliometric analysis of 1390 research articles collected from the Scopus database from 2000 to 2021. The study accomplished performance and science mapping analysis using Bibliometrix and VOSViewer software. The study shows an increasing publication trend. The most productive country was the USA (259 publications with 8400 citations), and the most productive institution was the University of California (33 publications). The study found that Cole MA was the most relevant author in this area by considering multiple matrices. By using keywords, conceptual structure, and bibliographic coupling analysis, the study suggests that future studies can be conducted on climate change, carbon leakage, climate policy, environmental protection, air pollution, economic growth, carbon dioxide emission, emission trading, abatement cost, environmental performance, green supply chain management, composition effect, carbon footprints, and multi-regional input-output model. The current study provides scholars and practitioners interested in trade and environmental interlinkages with a comprehensive overview of the domain by presenting readers with significant studies, authors, universities, concepts, and sources. Further, the study results will be helpful for scholars to get insights into the current research development trends and research themes in the trade and environmental regulation field. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.","Bibliometric analysis; Bibliometrix; Environment; Performance analysis; Trade; VOSViewer","Air Pollution; Bibliometrics; Carbon Dioxide; Commerce; Internationality; California; United States; carbon dioxide; abatement cost; bibliography; carbon dioxide; carbon emission; carbon footprint; emissions trading; performance assessment; software; supply chain management; trade-environment relations; air pollution; bibliometrics; commercial phenomena; international cooperation","","carbon dioxide, 124-38-9, 58561-67-4; Carbon Dioxide, ","","","National Institute of Technology Karnataka, Surathkal, NITK","The authors wish to acknowledge the National Institute of Technology Karnataka, Surathkal, India, for supporting the study. They also thank the anonymous reviewers for their valuable comments and suggestions.","Aichele R., Felbermayr G., Kyoto and the carbon footprint of nations, J Environ Econ Manag, 63, 3, pp. 336-354, (2012); Akbostanci E., Tunc G.I., Turut-Asik S., Pollution haven hypothesis and the role of dirty industries in Turkey’s exports, Environ Dev Econ, 12, 2, (2007); Antweiler W., Copeland B.R., Taylor M.S., Is free trade good for the environment?, Am Econ Rev, 91, 4, pp. 877-908, (2001); Appio F.P., Cesaroni F., Di Minin A., Visualizing the structure and bridges of the intellectual property management and strategy literature: a document co-citation analysis, Scientometrics, 101, 1, pp. 623-661, (2014); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, J Informet, 11, 4, pp. 959-975, (2017); Babiker M.H., Climate change policy, market structure, and carbon leakage, J Int Econ, 65, 2, pp. 421-445, (2005); Bagayev I., Lochard J., EU air pollution regulation: a breath of fresh air for Eastern European polluting industries?, J Environ Econ Manag, 83, pp. 145-163, (2017); Baier-Fuentes H., Merigo J.M., Amoros J.E., Gaviria-Marin M., International entrepreneurship: a bibliometric overview, Int Entrep Manag J, 15, 2, pp. 385-429, (2019); Balogh J.M., Jambor A., The environmental impacts of agricultural trade: a systematic literature review, Sustainability, 12, 3, (2020); Barrett S., Strategic environmental policy and international trade, J Public Econ, 54, 3, pp. 325-338, (1994); Baumol W.J., Environmental protection, international spillovers and trade, (1971); Baumol W.J., Oates W.E., The theory of environmental policy, (1988); Berry H., Kaul A., Lee N., Follow the smoke: the pollution haven effect on global sourcing, Strateg Manag J, 42, 13, pp. 2420-2450, (2021); Blondel V.D., Guillaume J., Lambiotte R., Lefebvre E., Fast unfolding of communities in large networks, J Stat Mech: Theory Exp, 2008, 10, (2008); Bradford S.C., Sources of information on specific subjects, Engineering, 26, pp. 85-86, (1934); Bretas V.P.G., Alon I., Franchising research on emerging markets: bibliometric and content analyses, J Bus Res, 133, pp. 51-65, (2021); Brunel C., Pollution offshoring and emissions reductions in EU and US manufacturing, Environ Resour Econ, 68, pp. 621-641, (2017); Burguet R., Sempere J., Trade liberalization, environmental policy, and welfare, J Environ Econ Manag, 46, 1, pp. 25-37, (2003); Cai X., Lu Y., Wu M., Yu L., Does environmental regulation drive away inbound foreign direct investment? 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Toward a better understanding of the direct and conditional effects, Environ Resour Econ, 66, 2, pp. 293-338, (2017)","L. Padhan; School of Humanities, Social Sciences and Management, National Institute of Technology Karnataka, Mangalore, NH 66, Srinivas Nagar, Surathkal, Karnataka, -575025, India; email: lakshmana.207sm002@nitk.edu.in","","Springer Science and Business Media Deutschland GmbH","","","","","","09441344","","ESPLE","36626051","English","Environ. Sci. Pollut. Res.","Review","Final","All Open Access; Green Open Access","Scopus","2-s2.0-85145908792" -"Kilicoglu O.; Mehmetcik H.","Kilicoglu, Ozge (59813654000); Mehmetcik, Hakan (57200747923)","59813654000; 57200747923","Science mapping for radiation shielding research","2021","Radiation Physics and Chemistry","189","","109721","","","","36","10.1016/j.radphyschem.2021.109721","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111173756&doi=10.1016%2fj.radphyschem.2021.109721&partnerID=40&md5=d7a067301403608f7c4a73da131ca327","Uskudar University, Vocational School of Health Services, Department of Nuclear Technology and Radiation Protection, Istanbul, Turkey; Marmara University, Istanbul, Turkey","Kilicoglu O., Uskudar University, Vocational School of Health Services, Department of Nuclear Technology and Radiation Protection, Istanbul, Turkey; Mehmetcik H., Marmara University, Istanbul, Turkey","This article examines intellectual, conceptual, and social networks among academics, organizations, and countries, as well as quantifies the scientific production, assesses scientific quality and impacts in the field of radiation shielding. To this end, we use a bibliometric analysis to evaluate the radiation shielding publication record. The bibliographic search is carried out in the ISI Web of Science, and time span covers documents written from 2000 to 2020. Along with descriptive statistical tools, we utilize the R package “Bibliometrix” as a tool to perform bibliometric analysis in order to model networks among authors, articles, resources, references, keywords, institutions and countries. This investigation reveals substantial radiation shielding publishing trends, especially in terms of co-authorships, citations, institutional cooperation and author country of origin. © 2021 Elsevier Ltd","Bibliometric analysis; Citation analysis; Radiation shielding; Scientometrics","Information analysis; Quality control; Statistical mechanics; Bibliometrics analysis; Citation analysis; Coauthorship; Modeling networks; Scientometrics; Statistical tools; Time span; Web of Science; Article; citation analysis; drug industry; glioblastoma; human; journal impact factor; medical research; open access publishing; publication; publishing; social network; systematic review; Web of Science; writing; Radiation shielding","","","","","","","Andres A., Measuring Academic Research: How to Undertake a Bibliometric Study, (2009); Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, J. Informetr., 11, pp. 959-975, (2017); Bornmann L., Mutz R., Neuhaus C., Daniel H.-D., Citation counts for research evaluation: standards of good practice for analyzing bibliometric data and presenting and interpreting results, Ethics Sci. Environ. Polit., 8, pp. 93-102, (2008); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: how great is the impact?, Scientometrics, 105, pp. 1809-1831, (2015); Issa S.A.M., Saddeek Y.B., Sayyed M.I., Tekin H.O., Kilicoglu O., Radiation shielding features using MCNPX code and mechanical properties of the PbO-Na2O-B2O3-CaO-Al2O3-SiO2 glass systems, Compos. B Eng., 167, pp. 231-240, (2019); Issa S.A.M., Tekin H.O., Elsaman R., Kilicoglu O., Saddeek Y.B., Sayyed M.I., Radiation shielding and mechanical properties of Al2O3-Na2O-B2O3-Bi2O3 glasses using MCNPX Monte Carlo code, Mater. Chem. Phys., 223, pp. 209-219, (2019); Lawani S.M., Bibliometrics: its theoretical foundations, methods and applications, Libri., 31, (1981); Li R., Gu Y., Zhang G., Yang Z., Li M., Zhang Z., Radiation shielding property of structural polymer composite: continuous basalt fiber reinforced epoxy matrix composite containing erbium oxide, Compos. Sci. Technol., 143, pp. 67-74, (2017); Martin B.R., What can bibliometrics tell us about changes in the mode of knowledge production?, Prometheus, 29, pp. 455-479, (2011); Mering M., Bibliometrics: understanding author-, article-and journal-level metrics, Ser. Rev., 43, pp. 41-45, (2017); Moed H.F., The impact-factors debate: the ISI's uses and limits, Nature, 415, pp. 731-732, (2002); Neuhaus C., Daniel H.-D., Data sources for performing citation analysis: an overview, J. Doc., (2008); Shultis J.K., Faw R.E., Radiation Shielding, (2000); Tishkevich D.I., Grabchikov S.S., Grabchikova E.A., Vasin D.S., Lastovskiy S.B., Yakushevich A.S., Vinnik D.A., Zubar T.I., Kalagin I.V., Mitrofanov S.V., Yakimchuk D.V., Trukhanov A.V., Modeling of paths and energy losses of high-energy ions in single-layered and multilayered materials, IOP Conf. Ser. Mater. Sci. Eng., 848, (2020); Tishkevich D.I., Grabchikov S.S., Lastovskii S.B., Trukhanov S.V., Zubar T.I., Vasin D.S., Trukhanov A.V., Correlation of the synthesis conditions and microstructure for Bi-based electron shields production, J. Alloys Compd., 749, pp. 1036-1042, (2018); Van Leeuwen T.N., Visser M.S., Moed H.F., Nederhof T.J., Van Raan A.F.J., The Holy Grail of science policy: exploring and combining bibliometric tools in search of scientific excellence, Scientometrics, 57, pp. 257-280, (2003); Waltman L., van Eck N.J., van Leeuwen T.N., Visser M.S., van Raan A.F.J., Towards a new crown indicator: an empirical analysis, Scientometrics, 87, pp. 467-481, (2011)","O. Kilicoglu; Uskudar University, Vocational School of Health Services, Department of Nuclear Technology and Radiation Protection, Istanbul, Turkey; email: ozgekoglu@gmail.com","","Elsevier Ltd","","","","","","0969806X","","RPCHD","","English","Radiat. Phys. Chem.","Article","Final","","Scopus","2-s2.0-85111173756" -"Mirhashemi A.; Amirifar S.; Tavakoli Kashani A.; Zou X.","Mirhashemi, Ali (57738376100); Amirifar, Saeideh (36117715000); Tavakoli Kashani, Ali (55070928500); Zou, Xin (57195738728)","57738376100; 36117715000; 55070928500; 57195738728","Macro-level literature analysis on pedestrian safety: Bibliometric overview, conceptual frames, and trends","2022","Accident Analysis and Prevention","174","","106720","","","","25","10.1016/j.aap.2022.106720","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85131791089&doi=10.1016%2fj.aap.2022.106720&partnerID=40&md5=370db3c97cc54f5e0074e0e3dc43dfed","School of Civil Engineering, Iran University of Science and Technology, Tehran, Iran; Road Safety Research Center, Iran University of Science and Technology, Tehran, Iran; Institute of Transport Studies, Monash University, Clayton, 3800, VIC, Australia","Mirhashemi A., School of Civil Engineering, Iran University of Science and Technology, Tehran, Iran, Road Safety Research Center, Iran University of Science and Technology, Tehran, Iran; Amirifar S., School of Civil Engineering, Iran University of Science and Technology, Tehran, Iran, Road Safety Research Center, Iran University of Science and Technology, Tehran, Iran; Tavakoli Kashani A., School of Civil Engineering, Iran University of Science and Technology, Tehran, Iran, Road Safety Research Center, Iran University of Science and Technology, Tehran, Iran; Zou X., Institute of Transport Studies, Monash University, Clayton, 3800, VIC, Australia","Due to the high volume of documents in the pedestrian safety field, the current study conducts a systematic bibliometric analysis on the researches published before October 3, 2021, based on the science-mapping approach. Science mapping enables us to present a broad picture and comprehensive review of a significant number of documents using co-citation, bibliographic coupling, collaboration, and co-word analysis. To this end, a dataset of 6311 pedestrian safety papers was collected from the Web of Science Core Collection database. First, a descriptive analysis was carried out, covering whole yearly publications, most-cited papers, and most-productive authors, as well as sources, affiliations, and countries. In the next steps, science mapping was implemented to clarify the social, intellectual, and conceptual structures of pedestrian-safety research using the VOSviewer and Bibliometrix R-package tools. Remarkably, based on intellectual structure, pedestrian safety demonstrated an association with seven research areas: “Pedestrian crash frequency models”, “Pedestrian injury severity crash models”, “Traffic engineering measures in pedestrians’ safety”, “Global reports around pedestrian accident epidemiology”, “Effect of age and gender on pedestrians’ behavior”, “Distraction of pedestrians”, and “Pedestrian crowd dynamics and evacuation”. Moreover, according to conceptual structure, five major research fronts were found to be relevant, namely “Collision avoidance and intelligent transportation systems (ITS)”, “Epidemiological studies of pedestrian injury and prevention”, “Pedestrian road crossing and behavioral factors”, “Pedestrian flow simulation”, and “Walkable environment and pedestrian safety”. Finally, “autonomous vehicle”, “pedestrian detection”, and “collision avoidance” themes were identified as having the greatest centrality and development degrees in recent years. © 2022 Elsevier Ltd","Bibliomertix R-package; Bibliometrics; Pedestrian safety; Science mapping; Scientometric; VOSviewer","Accidents, Traffic; Bibliometrics; Humans; Pedestrians; Safety; Walking; Highway engineering; Intelligent systems; Intelligent vehicle highway systems; Pedestrian safety; Traffic control; Bibliomertix R-package; Bibliometric; Collisions avoidance; Conceptual structures; Intellectual structures; Literature analysis; Pedestrian injuries; Science mapping; Scientometrics; Vosviewer; bibliometrics; human; injury; pedestrian; prevention and control; safety; traffic accident; walking; Mapping","","","","","","","Aekbote K., Schuster P.J., Kankanala S.V., Sundararajan S., Rouhana S.W., The biomechanical aspects of pedestrian protection, Int. J. Veh. 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Prev., 32, 5, pp. 651-658, (2000); Lee C., Abdel-Aty M., Comprehensive analysis of vehicle–pedestrian crashes at intersections in Florida, Accid. Anal. Prev., 37, 4, pp. 775-786, (2005); Lefler D.E., Gabler H.C., The fatality and injury risk of light truck impacts with pedestrians in the United States, Accid. Anal. Prev., 36, 2, pp. 295-304, (2004); Li B., A bilevel model for multivariate risk analysis of pedestrians’ crossing behavior at signalized intersections, Transp. Res. Part B Methodol., 65, pp. 18-30, (2014); Li B., A model of pedestrians’ intended waiting times for street crossings at signalized intersections, Transp. Res. Part B Methodol., 51, pp. 17-28, (2013); Li D., Han B., Behavioral effect on pedestrian evacuation simulation using cellular automata, Saf. Sci., 80, pp. 41-55, (2015); Li G., Yang J., Simms C., A virtual test system representing the distribution of pedestrian impact configurations for future vehicle front-end optimization, Traffic Inj. Prev., 17, 5, pp. 515-523, (2016); Li G., Yang Y., Qu X., Deep Learning approaches on pedestrian detection in hazy weather, IEEE Trans. Ind. Electron., 67, 10, pp. 8889-8899, (2020); Li J., Goerlandt F., Reniers G., An overview of scientometric mapping for the safety science community: methods, tools, and framework, Saf. Sci., 134, (2021); Li J., Hale A., Output distributions and topic maps of safety related journals, Saf. Sci., 82, pp. 236-244, (2016); Li Y., Chen M., Zheng X., Dou Z., Cheng Y., Relationship between behavior aggressiveness and pedestrian dynamics using behavior-based cellular automata model, Appl. Math. Comput., 371, (2020); Li Y., Song L., Fan W.D., Day-of-the-week variations and temporal instability of factors influencing pedestrian injury severity in pedestrian-vehicle crashes: a random parameters logit approach with heterogeneity in means and variances, Anal. Methods Accid. Res., 29, (2021); Lim J., Amado A., Sheehan L., Van Emmerik R.E.A., Dual task interference during walking: the effects of texting on situational awareness and gait stability, Gait Posture, 42, 4, pp. 466-471, (2015); Lin M.-I.-B., Huang Y.-P., The impact of walking while using a smartphone on pedestrians’ awareness of roadside events, Accid. Anal. Prev., 101, pp. 87-96, (2017); Linn S., The injury severity score—importance and uses, Ann. Epidemiol., 5, 6, pp. 440-446, (1995); Liu H., Chen H., Hong R., Liu H., You W., Mapping knowledge structure and research trends of emergency evacuation studies, Saf. Sci., 121, pp. 348-361, (2020); Liu X.J., Yang J.K., Lovsund P., A study of influences of vehicle speed and front structure on pedestrian impact responses using mathematical models, Traffic Inj. Prev., 3, 1, pp. 31-42, (2002); Liu Y.C., Tung Y.C., Risk analysis of pedestrians’ road-crossing decisions: effects of age, time gap, time of day, and vehicle speed, Saf. Sci., 63, pp. 77-82, (2014); Llorca D.F., Milanes V., Alonso I.P., Gavilan M., Daza I.G., Perez J., Sotelo M.A., Autonomous pedestrian collision avoidance using a fuzzy steering controller, IEEE Trans. Intell. Transp. Syst., 12, 2, pp. 390-401, (2011); Lobjois R., Cavallo V., The effects of aging on street-crossing behavior: from estimation to actual crossing, Accid. Anal. Prev., 41, 2, pp. 259-267, (2009); Lobjois R., Cavallo V., Age-related differences in street-crossing decisions: the effects of vehicle speed and time constraints on gap selection in an estimation task, Accid. Anal. Prev., 39, 5, pp. 934-943, (2007); Lord D., Mannering F., The statistical analysis of crash-frequency data: a review and assessment of methodological alternatives, Transp. Res. Part A Policy Pract., 44, 5, pp. 291-305, (2010); Lord D., Washington S.P., Ivan J.N., Poisson, Poisson-gamma and zero-inflated regression models of motor vehicle crashes: balancing statistical fit and theory, Accid. Anal. Prev., 37, 1, pp. 35-46, (2005); MacKenzie E.J., Shapiro S., Eastham J.N., The abbreviated injury scale and injury severity score: levels of inter-and intrarater reliability, Med. Care, pp. 823-835, (1985); Mansfield T.J., Peck D., Morgan D., McCann B., Teicher P., The effects of roadway and built environment characteristics on pedestrian fatality risk: a national assessment at the neighborhood scale, Accid. Anal. Prev., 121, pp. 166-176, (2018); Mansuri F.A., Al-Zalabani A.H., Zalat M.M., Qabshawi R.I., Road safety and road traffic accidents in Saudi Arabia: a systematic review of existing evidence, Saudi Med. J., 36, 4, (2015); Marshall W.E., Garrick N.W., Effect of street network design on walking and biking, Transp. Res. Rec., 2198, 1, pp. 103-115, (2010); Martin A., Factors Influencing Pedestrian Safety: A Literature Review, (2006); Martin J.-L., Wu D., Pedestrian fatality and impact speed squared: Cloglog modeling from French national data, Traffic Inj. Prev., 19, 1, pp. 94-101, (2018); Martin R.F., Parisi D.R., Data-driven simulation of pedestrian collision avoidance with a nonparametric neural network, Neurocomputing, 379, pp. 130-140, (2020); Merigo J.M., Miranda J., Modak N.M., Boustras G., De La Sotta C., Forty years of Safety Science: a bibliometric overview, Saf. Sci., 115, pp. 66-88, (2019); Miles-Doan R., Alcohol use among pedestrians and the odds of surviving an injury: evidence from Florida law enforcement data, Accid. Anal. Prev., 28, 1, pp. 23-31, (1996); Miranda-Moreno L.F., Morency P., El-Geneidy A.M., The link between built environment, pedestrian activity and pedestrian–vehicle collision occurrence at signalized intersections, Accid. Anal. Prev., 43, 5, pp. 1624-1634, (2011); Modak N.M., Merigo J.M., Weber R., Manzor F., de Dios Ortuzar J., Fifty years of transportation research journals: a bibliometric overview, Transp. Res. Part A Policy Pract., 120, pp. 188-223, (2019); Mohamed M.G., Saunier N., Miranda-Moreno L.F., Ukkusuri S.V., A clustering regression approach: a comprehensive injury severity analysis of pedestrian–vehicle crashes in New York, US and Montreal, Canada, Saf. Sci., 54, pp. 27-37, (2013); Mokhtarimousavi S., A time of day analysis of pedestrian-involved crashes in California: Investigation of injury severity, a logistic regression and machine learning approach using HSIS data, Inst. Transp. Eng. ITE J., 89, 10, pp. 25-33, (2019)","A. Tavakoli Kashani; School of Civil Engineering, Iran University of Science and Technology, Tehran, Iran; email: alitavakoli@iust.ac.ir","","Elsevier Ltd","","","","","","00014575","","AAPVB","35700686","English","Accid. Anal. Prev.","Article","Final","","Scopus","2-s2.0-85131791089" -"Akyüz S.","Akyüz, Selahattin (57656324100)","57656324100","Bibliometric Analysis of Researches on Health Literacy; [Sağlık Okuryazarlığı Araştırmalarının Bibliyometrik Analizi]","2021","Genel Tip Dergisi","31","4","","402","416","14","2","10.54005/geneltip.975248","https://www.scopus.com/inward/record.uri?eid=2-s2.0-105009249371&doi=10.54005%2fgeneltip.975248&partnerID=40&md5=e83d604e628bcf5098162ec78c239caf","Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Turkey","Akyüz S., Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Turkey","Objective: Health literacy, which has gained importance for all stakeholders in recent years, can be defined as basic health information that will affect the decisions of individuals in accessing health services and their capacity to understand these services. In the literature, it is seen that the studies on health literacy have increased recently. The aim of this research is to present the scientific map of the field of health literacy strategically and thematically within the framework of the researches. Materials and Methods: The data used in this study were obtained from the Web of Science (WoS) database covering the years 1975-2019. The data obtained were analyzed and visualized in the R based Bibliometrix analysis program with the web interface provider Biblioshiny. Results: In the research, 808 documents were reached among 401 sources. There has been an increase in research on health literacy since 2004. The most publications have been made in the USA. The theme of “Health Literacy” has come to the fore in conceptual networks. It has been seen that the document published by Berkman stands out in the document co-citation network, the most important author in the central cluster in the author co-citation network is Baker, and the most important source in the central cluster in the reference network is the Journal of General Internal Medicine. Kripalani is the author with the most collaborative network and Northwestern University is the most collaborative institution. Conclusion: It is thought that the findings of this research will guide all relevant stakeholders. In addition, it was evaluated that scientific activities that will raise awareness about health literacy should be organized and supported. © 2021, Selcuk University. All rights reserved.","Bibliometric analysis; Biblioshiny; Bibliyometrix; Health literacy; Science mapping","","","","","","","","Kickbusch I, Pelikan J, Apfel F, Tsouros A., Health literacy, (2013); Baker DW, Williams MV, Parker RM, Gazmararian JA, Nurss J., Development of a brief test to measure functional health literacy, Patient Education and Counseling, 38, 1, pp. 33-42, (1999); Kripalani S, Weiss BD., Teaching about health literacy and clear communication, Journal of General Internal Medicine, 21, 8, pp. 888-890, (2006); Baker DW, Parker RM, Williams MV, Clark WS, Nurss J., The relationship of patient reading ability to self-reported health and use of health services, American Journal of Public Health, 87, 6, pp. 1027-1030, (1997); Nutbeam D, Kickbusch I., Advancing health literacy, a global challenge for the 21th century, Health Promot Int, 15, pp. 259-267, (2000); Zibellini J, Muscat DM, Kizirian N, Gordon A., Effect of health literacy interventions on pregnancy outcomes: A systematic review, Women and Birth, 34, 2, pp. 180-186, (2021); Nash S, Arora A., Interventions to improve health literacy among Aboriginal and Torres Strait Islander Peoples: A systematic review, BMC Public Health, 21, 1, pp. 1-15, (2021); Shnaigat M, Downie S, Hosseinzadeh H., Effectiveness of health literacy interventions on COPD self-management outcomes in outpatient settings: A systematic review, COPD: Journal of Chronic Obstructive Pulmonary Disease, pp. 1-7, (2021); Vernon JA, Trujillo A, Rosenbaum SJ, DeBuono B., Low health literacy: Implications for national health policy, (2007); Kondilis BK, Kiriaze IJ, Athanasoulia AP, Falagas ME., Mapping health literacy research in the European Union: A bibliometric analysis, PLoS One, 3, 6, (2008); Norman CD, Skinner HA., eHealth literacy: essential skills for consumer health in a networked world, Journal of Medical Internet Research, 8, 2, (2006); Sorensen K, Pelikan JM, Rothlin F, Et al., Health literacy in Europe: comparative results of the European health literacy survey (HLS-EU), European Journal of Public Health, 25, 6, pp. 1053-1058, (2015); Bozkurt H, Demirci H., Health literacy among older persons in Turkey, The Aging Male, 22, 4, pp. 272-277, (2019); Ozdemir H, Alper Z, Uncu Y, Bilgel N., Health literacy among adults: A study from Turkey, Health Education Research, 25, 3, pp. 464-477, (2010); Arias KM., Outbreak investigation, prevention, and control in health care settings: Critical issues in patient safety, (2010); Chen C., Science mapping: A systematic review of the literature, Journal of Data and Information Science, 2, 2, pp. 1-40, (2017); Kurutkan M, Orhan F., Kalite prensiplerinin görsel haritalama tekniğine göre bibliyometrik analizi: Sage Yayıncılık San, (2018); Kurutkan M, Orhan F., Sağlık politikası konusunun bilim haritalama teknikleri İle analizi, (2018); Zupic I, Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015); Aria M, Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bankson HL., Health literacy: An exploratory bibliometric analysis, 1997–2007, Journal of the Medical Library Association: JMLA, 97, 2, (2009); Shapiro RM., Health literacy: A bibliometric and citation analysis, (2010); Nasir A, Shaukat K, Hameed IA, Et al., A bibliometric analysis of corona pandemic in social sciences: a review of influential aspects and conceptual structure, IEEE Access, (2020); Guley AO, Kurutkan MN., Sağlık hizmetlerinde kalite kavramının bibliyometrik analizi: Çalışmalar ve eğilimler, Journal of Innovative Healthcare Practices, 2, 1, pp. 1-22, (2021); Bornmann L, Daniel HD., What do we know about the h index?, Journal of the American Society for Information Science and Technology, 58, 9, pp. 1381-1385, (2007); Harzing A-W., Reflections on the h-index, Business&Leadership, 1, 9, pp. 101-106, (2012); Thamaraiselvi M, Lakshmi S, Manthiramoorthi M., Correlation of authorship pattern, Lotka’s law and collaborative measures on research publications of Anna University: A bibliometric study, Library Philosophy and Practice, pp. 1-12, (2021); Wang C, Lim MK, Zhao L, Et al., The evolution of Omega-The International Journal of Management Science over the past 40 years: A bibliometric overview, Omega, 93, (2020); Bazm S, Bazm R, Sardari F., Growth of health literacy research activity in three Middle Eastern countries, BMJ Health & Care Informatics, 26, 1, (2019); Baji F, Azadeh F, Parsaei Mohammadi P, Parmah S., Mapping intellectual structure of health literacy area based on co-word analysis in web of science database during the years 1993-2017, Health Information Management, 15, 3, pp. 139-145, (2018); Sanders LM, Federico S, Klass P, Abrams MA, Dreyer B., Literacy and child health: A systematic review, Archives of Pediatrics & Adolescent Medicine, 163, 2, pp. 131-140, (2009)","S. Akyüz; Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Altındağ, Ankara, 06200, Turkey; email: selahattinakyuz@hotmail.com","","Selcuk University","","","","","","26023741","","","","Turkish","Genel Tip Dergisi.","Article","Final","","Scopus","2-s2.0-105009249371" -"Milićević A.; Vučković T.; Krstić D.; Ivić A.","Milićević, Andela (57223112750); Vučković, Teodora (57203204255); Krstić, Dušan (57612795500); Ivić, Aleksandar (57223107433)","57223112750; 57203204255; 57612795500; 57223107433","Information Systems Integration in E-Government: A Bibliometric Analysis Approach","2023","2023 22nd International Symposium INFOTEH-JAHORINA, INFOTEH 2023","","","","","","","3","10.1109/INFOTEH57020.2023.10094140","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85156162800&doi=10.1109%2fINFOTEH57020.2023.10094140&partnerID=40&md5=3ffc02fbbdbba37b89c92e5e8063eab8","University of Novi Sad, Faculty of Technical Sciences, Department of Industrial Engineering and Management, Novi Sad, Serbia","Milićević A., University of Novi Sad, Faculty of Technical Sciences, Department of Industrial Engineering and Management, Novi Sad, Serbia; Vučković T., University of Novi Sad, Faculty of Technical Sciences, Department of Industrial Engineering and Management, Novi Sad, Serbia; Krstić D., University of Novi Sad, Faculty of Technical Sciences, Department of Industrial Engineering and Management, Novi Sad, Serbia; Ivić A., University of Novi Sad, Faculty of Technical Sciences, Department of Industrial Engineering and Management, Novi Sad, Serbia","The traditional way of doing business can no longer meet the needs of work and clients, and it is necessary to introduce information systems and new technologies into work processes and corporate management. Worldwide, governments have been developing information systems and e-government to provide better services to their citizens. Integration of information systems in public sectors, especially in government, can maximize business performance and productivity in relations between government and citizens. This paper aims to conduct a bibliometric analysis of the integration of information systems in e-government by evaluating bibliographic data for all articles indexed in the Scopus database. The science mapping and bibliometric analysis were conducted using the ""bibliometrix""R package. Also, a graphical analysis of the bibliographic data was performed using VoSviewer. This study identified the main information about the implementation of information systems integration in e-government, the most productive authors, the most productive countries, the main keywords, and the main sources. © 2023 IEEE.","bibliometrix; e-government; information systems integration; public sectors","e-government; Information management; Information use; Integration; Analysis approach; Bibliographic data; Bibliometrics analysis; Bibliometrix; Corporate management; e-Government; Information systems integration; Process management; Public sector; Work process; Information systems","","","","","","","Stefanovic D., Milicevic A., Havzi S., Lolic T., Ivic A., Information Systems Success Models in the E-Government : Context: A Systematic Literature Review, 2021 20th International Symposium INFOTEH-JAHORINA (INFOTEH), pp. 1-6, (2021); Rakic S., Pero M., Sianesi A., Marjanovic U., Digital Servitization and Firm Performance: Technology Intensity Approach, Eng. Econ, 33, 4, pp. 398-413, (2022); Stefanovic D., Marjanovic U., Delic M., Culibrk D., Lalic B., Assessing the success of e-government systems: An employee perspective, Inf. Manage, 53, 6, pp. 717-726, (2016); Ciric D., Lolic T., Gracanin D., Stefanovic D., Lalic B., The Application of ICT Solutions in Manufacturing Companies in Serbia, Adv. Prod. Manag. Syst. Smart Digit. Manuf, 592, pp. 122-129, (2020); Abdulkareem A.K., Mohd Ramli R., Does trust in e-government influence the performance of e-government? An integration of information system success model and public value theory, Transform. Gov. People Process Policy, 16, 1, pp. 1-17, (2022); Ivic A., Milicevic A., Krstic D., Kozma N., Havzi S., The Challenges and Opportunities in Adopting AI, IoT and Blockchain Technology in E-Government: A Systematic Literature Review, 2022 International Conference on Communications, Information, Electronic and Energy Systems (CIEES), pp. 1-6, (2022); Jochen Scholl H.J., Klischewski R., E-Government Integration and Interoperability: Framing the Research Agenda, Int. J. Public Adm, 30, 8-9, pp. 889-920, (2007); Beric D., Havzi S., Lolic T., Simeunovic N., Stefanovic D., Development of the MES software and Integration with an existing ERP Software in Industrial Enterprise, 2020 19th International Symposium INFOTEH-JAHORINA (INFOTEH), East Sarajevo, Bosnia and Herzegovina, pp. 1-6, (2020); Ari-Veikko A., Wing L., Information Systems Integration in EGovernment, Electronic Government, (2008); Bhatt G.D., Grover V., Types of information technology capabilities and their role in competitive advantage: An empirical study, J. Manag. Inf. Syst, 22, 2, pp. 253-277, (2005); Klischewski R., Scholl H.J., Information quality as a common ground for key players in e-Government integration and interoperability, Proc. Annu. Hawaii Int. Conf. Syst. Sci, 4, 100, (2006); Barki H., Pinsonneault A., A model of organizational integration, implementation effort, and performance, Organ. Sci, 16, 2, pp. 165-179, (2005); Cheng-Yi Wu R., Enterprise integration in e-government, Transform. Gov. People Process Policy, 1, 1, pp. 89-99, (2007); Dakic D., Stefanovic D., Lolic T., Sladojevic S., Anderla A., Production planning business process modelling using UML class diagram, 2018 17th International Symposium Infotehjahorina (INFOTEH), pp. 1-6, (2018); Mohamed N., Mahadi B., Miskon S., Haghshenas H., Adnan H.M., Information System Integration: A Review of Literature and a Case Analysis, Math. Comput. Contemp. Sci, (2013); Gupta B.M., Bhattacharya S., Bibliometric approach towards mapping the dynamics of science and technology, Desidoc Bull. Inf. Technol, 24, 1, pp. 3-8, (2004); Merediz-Sola I., Bariviera A.F., A bibliometric analysis of bitcoin scientific production, Res. Int. Bus. Finance, 50, pp. 294-305, (2019); McBurney M.K., Novak P.L., What is bibliometrics and why should you care?, Ieee Int. Prof. Commun. Conf, pp. 108-114, (2002); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, 3, pp. 1809-1831, (2015); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr, 11, 4, pp. 959-975, (2017)","A. Milićević; University of Novi Sad, Faculty of Technical Sciences, Department of Industrial Engineering and Management, Novi Sad, Serbia; email: andjela.milicevic@uns.ac.rs","","Institute of Electrical and Electronics Engineers Inc.","Enterprise Europe Network of Republic of Srpska; MTEL Banja Luka; Municipality of East Ilidza","22nd International Symposium INFOTEH-JAHORINA, INFOTEH 2023","15 March 2023 through 17 March 2023","East Sarajevo","187924","","978-166547546-4","","","English","Int. Symp. INFOTEH-JAHORINA, INFOTEH","Conference paper","Final","","Scopus","2-s2.0-85156162800" -"Gupta N.; Chakravarty R.","Gupta, Nidhi (57223388876); Chakravarty, Rupak (36674495400)","57223388876; 36674495400","Science Mapping Analysis of Digital Humanities research: A scientometric study","2021","Library Philosophy and Practice","2021","","","","","","2","","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115738973&partnerID=40&md5=a493750aab4523b0144ce35f33488d52","Department of Library and Information Science, Panjab University, Chandigarh, India","Gupta N., Department of Library and Information Science, Panjab University, Chandigarh, India; Chakravarty R., Department of Library and Information Science, Panjab University, Chandigarh, India","Purpose– The purpose of this paper is to use scientometric analysis to identify the current state of the academic literature regarding Digital humanities(DH) and analyze its knowledge base such as highly contributing researchers, countries, organizations, sources, keyword analysis and subject areas. Design/methodology/approach– This study carried out a scientometric study on DH literature, 2909 records were retrieved from Scopus database, time span chosen as 2005-2020 as 15 years of study in DH research area. Retrieved data can be analyzed by using VOSviewer,Bibliometrix R package scientometric tools. Findings – The findings suggested the enormous proliferation of DH research during last 15 years, social sciences scores highest position in subject category with (30.3%) publications. Hyvonen, Eero is the higly contributing author. USA is the most productive country. The King's College London tops as the highly productive institutions in the DH research area. This study also shows strong co-authorship pattern between authors, countries and institutions. The most frequently used keyword in DH research is “Digital humanities”. Originality/value– This study on scientometric analysis in DH literature may inform researchers and scholars of current trends and development in DH research area. © 2021, Library Philosophy and Practice. All Rights Reserved.","Bibliometrix R package; Co-authorship; Co-occurrence; Digital Humanities; Scientometrics; VOSviewer","","","","","","","","Benito-Santos A., Theron R., Pilaster: A collection of citation metadata extracted from publications on visualization for the digital humanities, Paper presented at the Proceedings - 2020 IEEE 5th Workshop on Visualization for the Digital Humanities, pp. 24-29, (2020); Clarke TC, Black LI, Stussman BJ, Barnes PM, Nahin RL., Trends in the Use of Complementary Health Approaches Among Adults: United States, 2002–2012, National Health Statistics Reports, (2015); Su H.N., Lee P.C., Mapping knowledge structure by keyword co-occurrence: a first look at journal papers in technology foresight, Scientometrics, 85, 1, pp. 65-79, (2010); Borner K., Chen C., Boyack K.W., Visualizing knowledge domains, Annu. Rev. Inf. Sci. Technol, 37, 1, (2003); Kemppainen LM, Kemppainen TT, Reippainen JA, Salmenniemi ST, Vuolanto PH., Useofcomplementary and alternative medicine in Europe: Health-related and sociodemographic determinants, Scandinavian Journal of Public Health, pp. 1-8, (2017); Lopez Martinez R. E., Sierra G., Research Trends in the International Literature on Natural Language Processing, 2000-2019 — A Bibliometric Study, Journal of Scientometric Research, 9, 3, pp. 310-318, (2020); McCarty W., Humanities Computing: Essential Problems, Experimental Practice, Literary and Linguistic Computing, 17, 1, pp. 103-125, (2002); Mokhtari H., Barkhan S., Haseli D., Saberi M. K., A bibliometric analysis and visualization of the Journal of Documentation: 1945–2018, Journal of Documentation, 77, 1, pp. 69-92, (2020); Mone G., What’s next for digital humanities? New computational tools spur advances in an evolving field, Communications of the ACM, 59, 6, pp. 20-21, (2016); Tang M, Cheng Y.J., Chen K.H., A longitudinal study of intellectual cohesion in digital humanities using bibliometric analyses, Scientometrics113, pp. 985-1008, (2017); Wang Q., Distribution features and intellectual structures of digital humanities, Journal of Documentation, 74, 1, pp. 223-246, (2018); Wang X., Tan X., Li H., The Evolution of Digital Humanities in China, Library Trends, 69, 1, pp. 7-29, (2020); Yang M., Wang M., Wang H., Yang G., Liu H., Exploring the transdisciplinary nature of digital humanities, Paper presented at the Proceedings of the ACM/IEEE Joint Conference on Digital Libraries, pp. 553-554, (2020); Zhang Y., Su F., Hubschman B., A content analysis of job advertisements for digital humanities-related positions in academic libraries, The Journal of Academic Librarianship, 47, 1, (2021); Mulchenko Z.M., Measurement of science. Study of the development of science as an information process, Proc. Natl. Acad. Sci. U. S. A, 405, 4, (1969)","N. Gupta; Department of Library and Information Science, Panjab University, Chandigarh, India; email: nidhigupta@pu.ac.in","","University of Nebraska-Lincoln","","","","","","15220222","","","","English","Libr. Philos. Pract.","Article","Final","","Scopus","2-s2.0-85115738973" -"Celenta R.; Cucino V.; Feola R.; Parente R.","Celenta, Ricky (58162833600); Cucino, Valentina (57130965100); Feola, Rosangela (55874352600); Parente, Roberto (55873427100)","58162833600; 57130965100; 55874352600; 55873427100","Towards Innovation 5.0: The Role of Corporate Entrepreneurship","2024","Springer Proceedings in Complexity","","","","451","463","12","5","10.1007/978-3-031-44721-1_34","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182015312&doi=10.1007%2f978-3-031-44721-1_34&partnerID=40&md5=0a9addec07cc557e2dac35f764895b11","University of Salerno, SA, Fisciano, 84084, Italy; Sant’Anna School of Advanced Studies, PI, Pisa, Italy","Celenta R., University of Salerno, SA, Fisciano, 84084, Italy; Cucino V., Sant’Anna School of Advanced Studies, PI, Pisa, Italy; Feola R., University of Salerno, SA, Fisciano, 84084, Italy; Parente R., University of Salerno, SA, Fisciano, 84084, Italy","Recently, there has been a widespread recognition of Corporate Entrepreneurship (CE) as a means to facilitate innovation within firms. In this context, it is important to revisit the concept of innovation, through the lenses of Industry 5.0 and Society 5.0, in order to understand the role of innovation in this context. More specifically, Innovation 5.0 can be defined as an approach to support the development of resilient, human-centered, sustainable, and digitally driven businesses. Despite the interest in this topic, there is a lack of recent literature that examines the relationship between CE and innovation processes, resulting in a fragmented body of knowledge. The primary objective of this paper is to contribute to the existing literature on Corporate Entrepreneurship by bridging the gap and focusing on the role of CE in innovation processes. The aim is to gain a deeper understanding of how CE impacts business innovation activities and to highlight how CE can support companies in developing innovations that align with the Industry 5.0 paradigm. To achieve our goals, we conduct a Bibliometric Analysis employing and Bibliographic Coupling analysis to find linkages between the CE and Innovation literature. More specifically, an ad hoc protocol has been developed for this BA. The selection of articles occurred in three steps, with Scopus being the chosen database due to its extensive coverage of indexed publications. Two tools were used in this study: VOSviewer software for constructing and visualizing bibliometric networks, with magazines, and researchers, based on common citations or paternity relationships and Bibliometrix, an R package for running extensive science mapping analysis which allows authors to perform analyses and graphs for sources, author, and document level and conceptual, intellectual, and social knowledge structures. The analysis highlights six discussion topics with theoretical e practical implications how CE activities can contribute to defining a new approach to innovation within firms, referred to as Innovation 5.0. These findings shed light on the ways in which CE can play a pivotal role in shaping innovative strategies and practices within organizations. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.","Bibliometric analysis; Corporate entrepreneurship; Industry 5.0; Innovation; Literature review","","","","","","","","Burgelman R.A., Corporate entrepreneurship and strategic management: Insights from a process study, Manage. Sci., 29, pp. 1349-1364, (1983); Guth W.D., Ginsberg A., Guest editors’ introduction: Corporate entrepreneurship, Strat. Manage. J., 11, pp. 5-15, (1990); Hornsby J.S., Kuratko D.F., Montagno R.V., Perception of internal factors for corporate entrepreneurship: A comparison of Canadian and U.S. managers. Entrepreneurship Theor, Pract, 24, 2, pp. 9-24, (1999); Pinchot G., Intrapreneuring: Why You Don’t have to Leave the Corporation to Become an Entrepreneur, (1985); Block Z., Macmillan I., Corporate Venturing: Creating New Businesses within the Firm, (1993); Vesper K.H., Three faces of corporate entrepreneurship: A pilot study, Frontiers of Entrepreneurship Research, pp. 294-326, (1984); Schollhammer H., Internal corporate entrepreneurship, Encyclopedia of Entrepreneurship, pp. 209-223, (1982); Jones G.R., Butler J.E., Managing internal corporate entrepreneurship: An agency theory, J. Manag., 18, pp. 733-749, (1992); Zahra S.A., Predictors and financial outcomes of corporate entrepreneurship: An exploratory study, J. Bus. Ventur., 6, 4, pp. 259-285, (1991); Sharma P., Chrisman J.J., Toward a reconciliation of the definitional issues in the field of corporate entrepreneurship, Entrep. Theory Pract., 23, 3, pp. 11-27, (1999); Stevenson H.H., Jarillo J.C., A paradigm of entrepreneurship: Entrepreneurial management, Strateg. Manag. J., 11, pp. 17-27, (1990); Dess G.G., Lumpkin G.T., The role of entrepreneurial orientation in stimulating effective corporate entrepreneurship, Acad. Manag. Exec., 19, 1, pp. 147-156, (2005); Schumpeter J.A., The Theory of Economic Development, (1934); Gartner W.B., What are we talking about when we talk about entrepreneurship?, J. Bus. Ventur., 5, pp. 15-28, (1990); Miller D., The correlates of entrepreneurship in three types of firms, Manage. Sci., 29, 7, pp. 770-791, (1983); Covin J.G., Slevin D.P., Strategic management of small firms in hostile and benign environments, Strateg. Manag. J., 10, pp. 75-87, (1989); Covin J.G., Slevin D.P., A conceptual model of entrepreneurship as firm behavior, Entrepreneurship Theor. Pract., 16, 1, pp. 7-26, (1991); Covin J.G., Lumpkin G.T., Entrepreneurial orientation theory and research: Reflections on a needed construct, Entrep. Theory Pract., 35, 5, pp. 855-872, (2011); Jennings D.F., Lumpkin J.R., Functioning modeling corporate entrepreneurship: An empirical integrative analysis, J. Manag., 15, 3, pp. 485-502, (1989); Zahra S.A., Environment, corporate entrepreneurship, and financial performance: a taxonomic approach, J. Bus. Ventur., 8, 4, pp. 319-340, (1993); Zahra S.A., Covin J.G., Contextual influences on the corporate entrepreneurship-performance relationship: A longitudinal analysis, J. Bus. Ventur., 10, pp. 43-58, (1995); Zahra S.A., Governance, ownership, and corporate entrepreneurship: The moderating impact of industry technological opportunities, Acad. Manag. J., 39, 6, pp. 1713-1735, (1996); Covin J.G., Miles M.P., Corporate entrepreneurship and the pursuit of competitive advantage, Entrep. Theory Pract., 23, pp. 47-63, (1999); Rogers E.M., Diffusion of Innovation, (1962); Garcia R., Calantone R., A critical look at technological innovation typology and innovativeness terminology: A literature review, J. Product Innov. Manage., 19, pp. 110-132, (2002); Stopford J.M., Baden-Fuller C.W.F., Creating corporate entrepreneurship, Strateg. Manag. J., 15, 7, pp. 521-536, (1994); Phan P.H., Wright M., Ucbasaran D., Et al., Corporate entrepreneurship: Current research and future directions, J. Bus. Ventur., 24, 3, pp. 197-205, (2009); Eisenhardt K.M., Graebner M.E., Theory building from cases: Opportunities and challenges, Acad. Manag. J., 50, 1, pp. 25-32, (2007); Dess G.G., Ireland R.D., Zahra S.A., Floyd S.W., Janney J.J., Lane P.J., Emerging issues in corporate entrepreneurship, J. Manag., 29, 3, pp. 351-378, (2003); Narayanan V.K., Yang Y., Zahra S.A., Corporate venturing and value creation: A review and proposed framework, Res. Policy, 38, 1, pp. 58-76, (2009); Akbari M., Padash H., Shahabaldini Parizi Z., Rezaei H., Shahriari E., Khosravani A., A bibliometric review of green innovation research: Identifying knowledge domain and network, Qual. Quant., 56, pp. 3993-4023, (2022); Suominen A., Seppanen M., Dedehayir O., A bibliometric review on innovation systems and ecosystems: A research agenda, Eur. J. Innov. Manag., 22, 2, pp. 335-360, (2019); Rey-Marti A., Ribeiro-Soriano D., Palacios-Marques D., A biblio-metric analysis of social entrepreneurship, J. Bus. Res. Elsevier, 69, 5, pp. 1651-1655, (2016); Lampe J., Kraft P.S., Bausch A., Mapping the field of research on entrepreneurial organizations (1937–2016): A bibliometric analysis and research agenda, Entrep. Theory Pract, 44, 4, pp. 784-816, (2014); Cucino V., Passarelli M., Di Minin A., Cariola A., Neuroscience approach for management and entrepreneurship: A bibliometric analysis, Eur. J. Innov. Manag., 25, 6, pp. 295-319, (2022); Morris M.H., Sexton D.L., The concept of entrepreneurial intensity: Implications for company performance, J. Bus. Res., 36, pp. 5-13, (1996); Lumpkin G.T., Dess G.G., Clarifying the entrepreneurial orientation construct and linking it to performance, Acad. Manag. Rev., 21, 1, pp. 135-172, (1996); Miller D., Friesen P.H., Innovation in conservative and entrepreneurial firms: Two models of strategic momentum, Strateg. Manag. J., 3, 1, pp. 1-25, (1982); Hamel G., Bringing silicon valley inside, Harvard Bus. Rev., 77, 5, (1999); Ferreira F.A., Mapping the field of arts-based management: Bibliographic coupling and cocitation analyses, J. Bus. Res., 85, pp. 348-357, (2018); van Eck N.J., Waltman L., Dekker R., van den Berg J., A comparison of two techniques for bibliometric mapping: Multidimensional scaling and VOS, J. Am. Soc. Inform. Sci. Technol., 61, 12, pp. 2405-2416, (2010); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informet., 11, 4, pp. 959-975, (2017); Kanter R.M., Swimming in newstreams: Mastering innovation dilemmas, Calif. Manage. Rev., 31, 4, pp. 45-69, (1989); Ireland R.D., Hitt M.A., Sirmon D.G., A model of strategic entrepreneurship: The construct and its dimensions, J. Manag., 29, 6, pp. 963-989, (2003); Miles M.P., Covin J.G., Exploring the practice of corporate venturing: Some common forms and their organizational implications, Entrep. Theor. Pract., 26, 3, pp. 21-40, (2002); Kuratko D.F., Hornsby J.S., Hayton J., Corporate entrepreneurship: The innovative challenge for a new global economic reality, Small Bus. Econ., 45, pp. 245-253, (2015); Finkle T.A., Corporate entrepreneurship and innovation in Silicon Valley: The case of google, inc, Entrep. Theory Pract., 36, 4, pp. 863-884, (2012); Kogut B., Zander U., Knowledge of the firm, combinative capabilities, and the replication of technology, Organ. Sci., 3, 3, pp. 383-397, (1992); Nonaka I., A dynamic theory of organizational knowledge creation, Organ. Sci., 5, 1, pp. 14-37, (1994); Christensen K.S., Enabling intrapreneurship: The case of a knowledge-intensive industrial company, Eur. J. Innov. Manag., 8, 3, pp. 305-322, (2005); Alpkan L., Bulut C., Gunday G., Ulusoy G., Kilic K., Organizational support for intrapreneurship and its interaction with human capital to enhance innovative performance, Manage. Decis., 48, 5, pp. 732-755, (2010); Castrogiovanni G.J., Urbano D., Loras J., Linking corporate entrepreneurship and human resource management in SMEs, Int. J. Manpow., 32, 1, pp. 34-47, (2011); Hayton J.C., Promoting corporate entrepreneurship through human resource management practices: A review of empirical research, Hum. Resour. Manag. Rev., 15, 1, pp. 21-41, (2005); Kuratko D.F., Ireland R.D., Hornsby J.S., Improving firm performance through entrepreneurial actions: Acordia’s corporate entrepreneurship strategy, Acad. Manage. Executive, 15, 4, pp. 60-71, (2001); Schmelter R., Mauer R., Borsch C., Brettel M., Boosting corporate entrepreneurship through hrm practices: Evidence from German smes, Hum. Resour. Manage., 49, 4, pp. 715-741, (2010); Amabile T.M., Conti R., Coon H., Lazenby J., Herron M., Assessing the work environment for creativity, Acad. Manag. J., 39, 5, pp. 1154-1184, (1996); Drach-Zahavy A., Interorganizational teams as boundary spanners: The role of team diversity, boundedness, and extra team links, Eur. J. Work Organ. Psychol., 20, 1, pp. 89-118, (2011); Oldham G.R., Cummings A., Employee creativity: Personal and contextual factors at work, Acad. Manag. J., 39, 3, pp. 607-634, (1996); Barringer B.R., Bluedorn A.C., The relationship between corporate entrepreneurship and strategic management, Strateg. Manag. J., 20, 5, pp. 421-444, (1999); Antoncic B., Hisrich R.D., Intrapreneurship, Construct Refinement and Cross-Cultural Validation. J. Bus. Ventur., 16, 5, pp. 495-527, (2001); Knight G.A., Cross-cultural reliability and validity of a scale to measure firm entrepreneurial orientation, J. Bus. Ventur., 12, pp. 213-225, (1997); Zahra S.A., George G., Absorptive capacity: A review, reconceptualization, and extension, Acad. Manag. Rev., 27, 2, pp. 185-203, (2002); Antoncic B., Hisrich R.D., Corporate entrepreneurship contingencies and organizational wealth creation, J. Manage. Dev., 23, 6, pp. 518-550, (2004); Zahra S.A., Neubaum D.O., Huse M., Entrepreneurship in medium-size companies: Exploring the effects of ownership and governance systems, J. Manag., 26, 5, pp. 947-976, (2000); Kuratko D.F., Audretsch D.B., Clarifying the domains of corporate entrepreneurship, Int. Entrepreneurship Manage. J., 9, 3, pp. 323-335, (2013); Real J.C., Leal A., Roldan J.L., Information technology as a determinant of organizational learning and technological distinctive competencies, Ind. Mark. Manage., 35, pp. 505-521, (2006); Heavey C., Simsek Z., Top management compositional effects on corporate entrepreneurship: The moderating role of perceived technological uncertainty, J. Product Innov. Manage., 30, 5, pp. 837-855, (2013); Shane S., Venkataraman S., The promise of entrepreneurship as a field of research, Acad. Manage. Rev., 25, 1, pp. 217-226, (2000); Gaglio C., Katz J., The psychological basis of opportunity identification: Entrepreneurial alertness, J. Small Bus. Econ., 16, pp. 11-95, (2001); Choi T.M., Kumar S., Yue X., Chan H.L., Disruptive technologies and operations management in the industry 4.0 era and beyond, Prod. Oper. Manage., (2022); Carayannis E.G., Dezi L., Gregori G., Calo E., Smart environments and techno-centric and human-centric innovations for industry and society 5.0: A quintuple helix innovation system view towards smart, sustainable, and inclusive solutions, J. Knowl. Econ. Springer; Portland Int. Center Manage. Eng. Technol. (PICMET), 13, 2, pp. 926-955, (2022); Parente R., Vesci M., Celenta R., From Industry 4.0 to Society 5.0, (2021); Kim K.C., Eltarabishy A., Bae Z.T., Humane entrepreneurship: How focusing on people can drive a new era of wealth and quality job creation in a sustainable world, J. Small Bus. Manage., 56, 1, pp. 10-29, (2018); Parente R., Eltarabishy A., Vesci M., Botti A., The epistemology of humane entrepreneurship: Theory and proposal for future research agenda, J. Small Bus. Manage., 56, 3, (2018); Parente R., El Tarabishy A., Botti A., Vesci M., Feola R., Humane entrepreneurship: Some steps in the development of a measurement scale, J. Small Bus. Manage., 59, 7, pp. 1-25, (2018); Parente R., Digitalization, consumer social responsibility, and humane entrepreneurship: Good news from the future, J. Int. Council Small Bus., 1, pp. 56-63, (2020); Feola R., Vesci M., Celenta R., Parente R., Crudele C., Corporate social entrepreneurship and Open Innovation: Evidence from ENI case, Electronic Conference Proceedings of Sinergie—Sima Management Conference Boosting Knowledge & Trust for a Sustainable Business, Milano, June 30Th and July 1St 2022, Pp. 481–486, (2022); Fernandes C., Ferreira J.J., Peris-Oritz M., Open innovation: Past, present and future trends, J. Organ. Chang. Manag., 32, 5, pp. 578-602, (2019); Alos G.A., Hytti U., Stakeholder theory approach to technology incubators, Int. J. Entrep. Behav. Res., 17, 6, pp. 607-625, (2011); Nien-He H., Meyer M., Rodin D., Van'T Klooster J., The social purpose of corporations, J. Br. Acad., 6, 1, pp. 49-73, (2018); Hitt M.A., Ireland R.D., Sirmon D.G., Trahms C.A., Strategic entrepreneurship: Creating value for individuals, organizations, and society, Acad. Manag. Perspect., 25, 2, pp. 57-75, (2011)","R. Celenta; University of Salerno, Fisciano, SA, 84084, Italy; email: rcelenta@unisa.it","Visvizi A.; Visvizi A.; Troisi O.; Corvello V.","Springer Science and Business Media B.V.","","International Research and Innovation Forum, RIIFORUM 2023","12 April 2023 through 14 April 2023","Krakowa","306089","22138684","978-303144720-4","","","English","Springer Proc. Complex.","Conference paper","Final","","Scopus","2-s2.0-85182015312" -"Gupta N.; Chakravarty R.","Gupta, Nidhi (57223388876); Chakravarty, Rupak (36674495400)","57223388876; 36674495400","Deciphering the Status of Library and Information Science Research in BRICS Nations: A Research Visualization Approach","2022","Journal of Library Administration","62","3","","404","418","14","6","10.1080/01930826.2022.2043695","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128374485&doi=10.1080%2f01930826.2022.2043695&partnerID=40&md5=6c050744c64f5f39c732337989996b8a","Doctoral Student, Department of Library and Information Science, Panjab University, Chandigarh, India; Professor, Department of Library and Information Science, Panjab University, Chandigarh, India","Gupta N., Doctoral Student, Department of Library and Information Science, Panjab University, Chandigarh, India; Chakravarty R., Professor, Department of Library and Information Science, Panjab University, Chandigarh, India","This paper aimed to evaluate the research trends in the discipline of library and information science (LIS) originating from the group of nations known as the BRICS (Brazil, Russia, India, China, and South Africa). The Web of Science core collection database (WoSCC) has been used to extract the published data during the period 1989–2020. Furthermore, VoSviewer and Bibliometrix R package software have been employed for bibliometric analysis of data and data visualization. Results from data analysis indicate that China has the highest number of publications. There is a positive upward trend in scientific publications and citation patterns. Scientometrics is the most influential journal with the highest number of publications. Wuhan University is the most productive institution. Fourie I (n = 233) attains the first rank as the most prolific author based on the highest number of research publications. The overall collaboration rate of LIS publications among BRICS countries is moderate. Deep learning, machine learning, sentiment analysis, altmetrics, and artificial intelligence are the leading topics in LIS research among BRICS nations. The study will be of interest or helpful for researchers and professionals in the LIS research field who are interested in learning more about research trends in LIS in the BRICS nations. © 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.","Bibliometrics; Bibliometrix R package; BRICS nations; co-authorship; conceptual structure; Library & Information Science Research; network mapping; science mapping; thematic evaluation; VoSviewer","","","","","","","","Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bornmann L., Wagner C., Leydesdorff L., BRICS countries and scientific excellence: A bibliometric analysis of most frequently cited papers, Journal of the Association for Information Science and Technology, 66, 7, pp. 1507-1513, (2015); (2019); (2021); (2016); Budd J.M., Productivity of U.S. LIS and ischool faculty, Library & Information Science Research, 37, 4, pp. 290-295, (2015); Castor K., Mota F.B., da Silva R.M., Cabral B.P., Maciel E.L., de Almeida I.N., Arakaki-Sanchez D., Andrade K.B., Testov V., Vasilyeva I., Zhao Y., Zhang H., Singh M., Rao R., Tripathy S., Gray G., Padayatchi N., Bhagwandin N., Swaminathan S., Kasaeva T., Kritski A., Mapping the tuberculosis scientific landscape among BRICS countries: A bibliometric and network analysis, Memórias Do Instituto Oswaldo Cruz, 115, pp. 1-8, (2020); Erfanmanesh M., Highly-Alted Articles in Library and Information Science, 14, 2, pp. 1-12, (2017); Esfahani H., Tavasoli K., Jabbarzadeh A., Big data and social media: A scientometrics analysis, International Journal of Data and Network Science, 3, 3, pp. 145-164, (2019); Hirsch J.E., An index to quantify an individual's scientific research output, Proceedings of the National Academy of Sciences of the United States of America, 102, 46, pp. 16569-16572, (2005); Kumar N., Asheulova N., Comparative analysis of scientific ouTPut of BRIC countries, Annals of Library and Information Studies, 58, 3, pp. 228-236, (2011); Leydesdorff L., Wagner C., Macro-level indicators of the relations between research funding and research ouTPut, Journal of Informetrics, 3, 4, pp. 353-362, (2009); Mangi L.D., BRIC’s research output in library & information science from 1996-2012 — A quantitative analysis, Open Journal of Social Sciences, 2, 10, pp. 62-73, (2014); Markusova V.A., Libkind A.N., Aversa E., Impact of competitive funding on research ouTPut in Russia, Collnet Journal of Scientometrics and Information Management, 6, 1, pp. 61-69, (2012); Miranda I.T.P., Moletta J., Pedroso B., Pilatti L.A., Picinin C.T., A review on green technology practices at BRICS Countries: Brazil, Russia, India, China, and South Africa, SAGE Open, 11, 2, (2021); Moed H.F., De Bruin R.E., Van Leeuwen T.N., New bibliometric tools for the assessment of national research performance: Database description, overview of indicators and first applications, Scientometrics, 33, 3, pp. 381-422, (1995); Nolin J., Astrom F., Turning weakness into strength: Strategies for future LIS, Journal of Documentation, 66, 1, pp. 7-27, (2010); Singh N., Influence of information technology in growth and publication of Indian LIS Literature, Libri, 59, 1, pp. 1-13, (2009); Tripathi M., Jeevan V.K.J., Babbar P., Mahemei L.K., Library and information science research in BRICS countries, Information and Learning Science, 119, 3-4, pp. 183-202, (2018); Upadhyaya P., Rajasekharan Pillai K., Management research outcome: A comparative assessment of BRICS nations, Studies in Higher Education, 44, 9, pp. 1567-1578, (2018); (2021); Wang X., Liu D., Ding K., Wang X., Science funding and research output: A study on 10 countries, Scientometrics, 91, 2, pp. 591-599, (2012); (2021)","N. Gupta; Panjab University, Chandigarh, 160014, India; email: nidhigupta@pu.ac.in","","Routledge","","","","","","01930826","","","","English","J. Libr. Adm.","Article","Final","All Open Access; Green Open Access","Scopus","2-s2.0-85128374485" -"Santosa F.A.","Santosa, Faizhal Arif (58176368900)","58176368900","Tips from the Experts Prior Steps into Knowledge Mapping: Text Mining Application and Comparison","2023","Issues in Science and Technology Librarianship","2023","102","","","","","2","10.29173/istl2736","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85153595052&doi=10.29173%2fistl2736&partnerID=40&md5=be8801ee02927510dfd59d278b65a612","Librarian for Polytechnic Institute of Nuclear Technology National Research and Innovation Agency, D. I. Yogyakarta, Indonesia","Santosa F.A., Librarian for Polytechnic Institute of Nuclear Technology National Research and Innovation Agency, D. I. Yogyakarta, Indonesia","Bibliometrics is increasingly being used by the knowledge community and librarians to easily analyze patterns in knowledge. In the field, the use of data from databases that provide bibliometric information is not always completely clean, so pre-processing is required. Several previous studies have shown that bibliometric analysis begins with a simple pre-processing step. The goal of this research is to use text mining to perform pre-processing to find the basic terms of the keywords that appear – to essentially construct a controlled vocabulary for a bibliographic dataset. The method used in this study is cleaning keywords with the stemming method using RapidMiner software. Bibliometrix was used to compare the results. A total of 85 keywords were combined into basic words. Using the built process, this study discovers differences in the network built between raw data and data that has been pre-processed, resulting in differences in the analysis that will be produced. The built process can also be reused in a variety of real-world situations. © 2023, Association of College and Research Libraries. All rights reserved.","Bibliometric mapping; Science mapping; Stemming; Text pre-processing","","","","","","","","Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Chapman P., Clinton J., Kerber R., Khabaza T., Reinartz T., Shearer C., Wirth R., CRISP-DM 1.0: Step-by-step data mining guide, SPSS, (2000); CheshmehSohrabi M., Mashhadi A., Using data mining, text mining, and bibliometric techniques to the research trends and gaps in the field of language and linguistics, Journal of Psycholinguistic Research, (2022); Gumpenberger C., Wieland M., Gorraiz J., Bibliometric practices and activities at the University of Vienna, Library Management, 33, 3, pp. 174-183, (2012); Han J., Kang H.-J., Kim M., Kwon G. H., Mapping the intellectual structure of research on surgery with mixed reality: Bibliometric network analysis (2000–2019), Journal of Biomedical Informatics, 109, (2020); Lamba M., Madhusudhan M., Application of sentiment analysis in libraries to provide temporal information service: A case study on various facets of productivity, Social Network Analysis and Mining, 8, 1, (2018); Li D., Dai F.-M., Xu J.-J., Jiang M.-D., Characterizing hotspots and frontier landscapes of diabetes-specific distress from 2000 to 2018: A bibliometric study, BioMed Research International, 2020, pp. 1-13, (2020); Moore M. T., Constructing a sentiment analysis model for LibQUAL+ comments, Performance Measurement and Metrics, 18, 1, pp. 78-87, (2017); Moral-Munoz J. A., Herrera-Viedma E., Santisteban-Espejo A., Cobo M. J., Software tools for conducting bibliometric analysis in science: An up-to-date review, El Profesional de La Información, 29, 1, (2020); Obidat A. H., Bibliometric analysis of global scientific literature on the accessibility of an integrated e-learning model for students with disabilities, Contemporary Educational Technology, 14, 3, (2022); Porter M. F., Snowball: A language for stemming algorithms, (2001); Schroer C., Kruse F., Gomez J. M., A systematic literature review on applying CRISP-DM process model, Procedia Computer Science, 181, pp. 526-534, (2021); Wang X., Xu Z., Skare M., A bibliometric analysis of Economic Research-Ekonomska Istraživanja (2007–2019), Economic Research-Ekonomska Istraživanja, 33, 1, pp. 865-886, (2020); Wang X., Xu Z., Su S.-F., Zhou W., A comprehensive bibliometric analysis of uncertain group decision making from 1980 to 2019, Information Sciences, 547, pp. 328-353, (2021); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Kalra V., Aggarwal R., Importance of text data preprocessing & implementation in RapidMiner [Paper presentation], Proceedings of the First International Conference on Information Technology and Knowledge Management, (2017); Text and web mining with RapidMiner","F.A. Santosa; Librarian for Polytechnic Institute of Nuclear Technology National Research and Innovation Agency, D. I. Yogyakarta, Indonesia; email: faizhal.arif.santosa@brin.go.id","","Association of College and Research Libraries","","","","","","10921206","","","","English","Issues Sci. Technol. Librariansh.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85153595052" -"Ribeiro H.; Barbosa B.; Moreira A.C.; Rodrigues R.","Ribeiro, Hugo (57315008200); Barbosa, Belém (57220870257); Moreira, António C. (57191493452); Rodrigues, Ricardo (35772768800)","57315008200; 57220870257; 57191493452; 35772768800","Churn in services – A bibliometric review; [Abandono en servicios - Una revisión bibliométrica]","2022","Cuadernos de Gestion","22","2","","97","121","24","14","10.5295/cdg.211509hr","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85130325136&doi=10.5295%2fcdg.211509hr&partnerID=40&md5=542f4a5f41b904d4c398d8231cca87b7","University of Porto, School of Economics and Management, Portugal; GOCVOPP - Research Unit on Governance, Competitiveness and Public Policies, University of Aveiro, Portugal; cef.UP – Center for Economics and Finance at UPorto, University of Porto, Portugal; Aveiro University, Department of Economics, Management, Industrial Engineering, and Tourism, Portugal; NECE-UBI - Research Center for Business Sciences, Universidade da Beira Interior, Portugal; INESCTEC—Institute for Systems and Computer Engineering, Technology and Science, Faculdade de Engenharia, Universidade do Porto, Portugal; Universidade da Beira Interior, Department of Business and Economics, Portugal","Ribeiro H., Aveiro University, Department of Economics, Management, Industrial Engineering, and Tourism, Portugal; Barbosa B., University of Porto, School of Economics and Management, Portugal, GOCVOPP - Research Unit on Governance, Competitiveness and Public Policies, University of Aveiro, Portugal, cef.UP – Center for Economics and Finance at UPorto, University of Porto, Portugal; Moreira A.C., GOCVOPP - Research Unit on Governance, Competitiveness and Public Policies, University of Aveiro, Portugal, Aveiro University, Department of Economics, Management, Industrial Engineering, and Tourism, Portugal, NECE-UBI - Research Center for Business Sciences, Universidade da Beira Interior, Portugal, INESCTEC—Institute for Systems and Computer Engineering, Technology and Science, Faculdade de Engenharia, Universidade do Porto, Portugal; Rodrigues R., NECE-UBI - Research Center for Business Sciences, Universidade da Beira Interior, Portugal, Universidade da Beira Interior, Department of Business and Economics, Portugal","The purpose of this article is to identify the most impactful research on customer churn and to map the conceptual and intellectual structure of its field of study. Data were collected from the WoS database, comprising 338 articles published between 1995 and 2020. Several bibliometric techniques were applied, including analysis of co-words, co-citation, bibliographic coupling, and co-authorship networks. R software and the Bibliometrix/Biblioshiny package were used to perform the analyses. The results identify the most active and influential authors, articles, and journals on the topic. More specifically, through co-citations and bibliographic coupling, it was possible to map the oldest articles (retrospective analysis) and the current research front (prospective analysis). The retrospective analysis, based on co-citations, revealed that the foundations of this research field are constructs such as quality of service, satisfaction, loyalty, and changing behaviors. The prospective analysis, performed through bibliographic coupling, revealed that current research is embedded in predictive analysis, clusters, data mining, and algorithms. The results provide robust guidance for further investigation in this field. © This article is distributed under the terms of the Creative Commons Atribution 4.0 Internacional License","Bibliographic coupling; Bibliometric analysis; Biblioshiny; Co-citation analysis; Customer churn; Science mapping","","","","","","","","Adebiyi S. O., Oyatoye E. O., Amole B. B., Relevant drivers for customers' churn and retention decision in the Nigerian mobile telecommunication industry, Journal of Competitiveness, 6, 3, (2016); Ahn J. H., Han S. P., Lee Y. S., Customer churn analysis: Churn determinants and mediation effects of partial defection in the Korean mobile telecommunications service industry, Telecommunications Policy, 30, 10-11, pp. 552-568, (2006); Ahn J., Hwang J., Kim D., Choi H., Kang S., A Survey on churn analysis in various business domains, IEEE Access, 8, (2020); Al-Mashraie M., Chung S. H., Jeon H. W, Customer switching behavior analysis in the telecommunication industry via push-pullmooring framework: A machine learning approach, Computers & Industrial Engineering, 144, (2020); Amin A., Shah B., Khattak A. M., Moreira F. J. L., Ali G., Rocha A., Anwar S., Cross-company customer churn prediction in telecommunication: A comparison of data transformation methods, International Journal of Information Management, 46, pp. 304-319, (2019); Amiri H., Daume H., Short text representation for detecting churn in microblogs, (2016); Anderson E. W, Fornell C., Lehmann D. R., Customer satisfaction, market share, and profitability - Findings from Sweden, Journal of Marketing, 58, 3, pp. 53-66, (1994); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Athanassopoulos A. 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N., A dynamic model ofthe duration ofthe customer's relationship with a continuous service provider: The role of satisfaction, Marketing Science, 17, 1, pp. 45-65, (1998); Buckinx W., Van den Poel D., Customer base analysis: Partial defection of behaviourally loyal clients in a non-contractual FMCG retail setting, European Journal of Operational Research, 164, 1, pp. 252-268, (2005); Burez J., Van den Poel D., CRM at a pay-TV company: Using analytical models to reduce customer attrition by targeted marketing for subscription services, Expert Systems with Applications, 32, 2, pp. 277-288, (2007); Burez J., Van den Poel D., Handling class imbalance in customer churn prediction, Expert Systems with Applications, 36, 3, pp. 4626-4636, (2009); Burnham T. A., Frels J. K., Mahajan V., Consumer switching costs: A typology, antecedents, and consequences, Journal of the Academy of Marketing Science, 31, 2, pp. 109-126, (2003); Callon M., Courtial J. P., Laville F., Co-word analysis as a tool for describing the network of interactions between basic and technological research - The case of polymer chemistry, Scientometrics, 22, 1, pp. 155-205, (1991); Callon M., Courtial J. P., Turner W A., Bauin S., From translations to problematic networks - An introduction to co-word analysis, Social Science Information Sur Les Sciences Sociales, 22, 2, (1983); Carrizo-Moreira A., Freitas-da Silva P. M., Ferreira-Moutinho V M., The effects of brand experiences on quality, satisfaction and loyalty: An empirical study in the telecommunications multiple-play service market, Innovar, 27, 64, pp. 23-38, (2017); Chen P. Y., Hitt L. M., Measuring switching costs and the determinants of customer retention in Internet-enabled businesses: A study of the Online brokerage industry, Information Systems Research, 13, 3, pp. 255-274, (2002); Cobo M. J., Lopez-Herrera A. 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C., Wiesel T., The predictive ability of different customer feedback metrics for retention, International Journal of Research in Marketing, 32, 2, pp. 195-206, (2015); Eck N. J. v., Waltman L., How to normalize co-occurrence data? An analysis of some well-known similarity measures, Journal ofthe American society for information science and technology, 60, 8, pp. 1635-1651, (2009); Ellegaard O., Wallin J. A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, 3, pp. 1809-1831, (2015); Eshghi A., Haughton D., Topi H., Determinants of customer loyalty in the wireless telecommunications industry, Telecommunications Policy, 31, 2, pp. 93-106, (2007); Ferreira F. A. F., Mapping the field of arts-based management: Bibliographic coupling and co-citation analyses, Journal of Business Research, 85, pp. 348-357, (2018); Fischbach K., Putzke J., Schoder D., Co-authorship networks in electronic markets research, Electronic Markets, 21, 1, pp. 19-40, (2011); Ganesh J., Arnold M. J., Reynolds K. E., Understanding the customer base of service providers: An examination of the differences between switchers and stayers, Journal of Marketing, 64, 3, pp. 65-87, (2000); Garfield E., Sher I. H., KEYWORDS-PLUS(TM) - Algorithmic derivative indexing, Journal of the American Society for Information Science, 44, 5, pp. 298-299, (1993); Gentile C., Spiller N., Noci G., How to sustain the customer experience:: An overview of experience components that co-create value with the customer, European management journal, 25, 5, (2007); Gerpott T. J., Ahmadi N., Regaining drifting mobile communication customers: Predicting the odds of success ofwinback efforts with competing risks regression, Expert Systems with Applications, 42, 21, pp. 7917-7928, (2015); Haddaway N. R. A. U. P. C. C., McGuinness L. A., PRIS-MA2020: R package and ShinyApp for producing PRISMA 2020 compliant flow diagrams (Version 0.0.2): Zenodo, (2021); Hadden J., Tiwari A., Roy R., Ruta D., Computer assisted customer churn management: State-of-the-art and future trends, Computers & Operations Research, 34, 10, pp. 2902-2917, (2007); Iglesias O., Singh J. J., Batista-Foguet J. M., The role of brand experience and affective commitment in determining brand loyalty, Journal of Brand Management, 18, 8, pp. 570-582, (2011); Jahromi A. T., Stakhovych S., Ewing M., Managing B2B customer churn, retention and profitability, Industrial Marketing Management, 43, 7, pp. 1258-1268, (2014); Jones M. A., Mothersbaugh D. L., Beatty S. 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B., Johnson E., Kaushansky H., Predicting subscriber dissatisfaction and improving retention in the wireless telecommunications industry, Ieee Transactions on Neural Networks, 11, 3, pp. 690-696, (2000); Neslin S. A., Gupta S., Kamakura W, Lu J. X., Mason C. H., Defection detection: Measuring and understanding the predictive accuracy of customer churn models, Journal of Marketing Research, 43, 2, pp. 204-211, (2006); Newman M. E., Girvan M., Finding and evaluating community structure in networks, Physical review E, 69, 2, (2004); Orman G. K., Labatut V., A comparison of community detection algorithms on artificial networks, Paper presented at the International conference on discovery science, (2009); Peters H. P. F., Vanraan A. F. J., Structuring scientific activities by coauthor analysis - An exercise on a university-faculty level, Scientometrics, 20, 1, pp. 235-255, (1991); Polo Y., Sese F J., How to Make Switching Costly The Role of Marketing and Relationship Characteristics, Journal of Service Research, 12, 2, pp. 119-137, (2009); Pons P., Latapy M., Computing communities in large networks using random walks, Paper presented at the International symposium on computer and information sciences, (2005); Prince J., Greenstein S., Does service bundling reduce churn?, Journal of Economics & Management Strategy, 23, 4, pp. 839-875, (2014); Pritchard A., Statistical bibliography or bibliometrics, Journal of documentation, 25, 4, pp. 348-349, (1969); Rajan Sachdeva R. R. S., Evaluating prediction of customer churn behavior based on artificial bee colony algorithm, International Journal of Engineering and Computer Science, 6, 1, (2017); Ramos-Rodriguez A. R., Ruiz-Navarro J., Changes in the intellectual structure of strategic management research: A bibliometric study ofthe Strategic Management Journal, 1980-2000, Strategic Management Journal, 25, 10, pp. 981-1004, (2004); Reichheld F F., Sasser W E., Zero defections - Quality comes to services, Harvard Business Review, 68, 5, pp. 105-111, (1990); Rust R. T., Zahorik A. J., Customer satisfaction, customer retention, and market share, Journal of Retailing, 69, 2, pp. 193-215, (1993); Sirapracha J., Tocquer G., Customer experience, brand image and customer loyalty in telecommunication services, the Int Conf Econ Bus Mark Manag, (2012); Small H., Co-citation in the scientific literature: A new measure of the relationship between two documents, Journal of the American Society for information Science, 24, 4, pp. 265-269, (1973); Small H., Visualizing science by citation mapping, Journal ofthe American Society for Information Science, 50, 9, pp. 799-813, (1999); Team R. 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J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Verbeke W., Dejaeger K., Martens D., Hur J., Baesens B., New insights into churn prediction in the telecommunication sector: A profit driven data mining approach, European Journal of Operational Research, 218, 1, pp. 211-229, (2012); Verbeke W., Martens D., Mues C., Baesens B., Building comprehensible customer churn prediction models with advanced rule induction techniques, Expert Systems with Applications, 38, 3, pp. 2354-2364, (2011); Wei C. P., Chiu I. T., Turning telecommunications call details to churn prediction: a data mining approach, Expert Systems with Applications, 23, 2, pp. 103-112, (2002); Yan E. J., Ding Y., Discovering author impact: A PageRank perspective, Information Processing & Management, 47, 1, pp. 125-134, (2011); Zeithaml V. A., Berry L. L., Parasuraman A., The behavioral consequences of service quality, Journal of Marketing, 60, 2, pp. 31-46, (1996); Zhang J., Yu Q., Zheng F. S., Long C., Lu Z. X., Duan Z. G., Comparing keywords plus of WOS and author keywords: A case study of patient adherence research, Journal of the Association for Information Science and Technology, 67, 4, pp. 967-972, (2016); Zhao D. Z., Strotmann A., Evolution of research activities and intellectual influences in information science 1996-2005: Introducing author bibliographic-coupling analysis, Journal of the American Society for Information Science and Technology, 59, 13, pp. 2070-2086, (2008); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","H. Ribeiro; Aveiro University, Department of Economics, Management, Industrial Engineering, and Tourism, Portugal; email: hugo.ribeiro@ua.pt","","Institute of Applied Business Economics","","","","","","11316837","","","","English","Cuad. Gest.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85130325136" -"Sadeqi-Arani Z.; Roozmand O.","Sadeqi-Arani, Zahra (57447049400); Roozmand, Omid (16550551300)","57447049400; 16550551300","A Review of Three Decades Using Agent-Based Modelling and Simulation in Marketing and Consumer Behavior","2023","Journal of Optimization in Industrial Engineering","16","2","","257","273","16","0","10.22094/JOIE.2023.1991052.2087","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186918230&doi=10.22094%2fJOIE.2023.1991052.2087&partnerID=40&md5=a19aa841326f811650dd8126f62923bb","Department of Management and Entrepreneurship, University of Kashan, Kashan, Iran; Department of Computer Engineering, Shahreza Campus, University of Isfahan, Isfahan, Iran","Sadeqi-Arani Z., Department of Management and Entrepreneurship, University of Kashan, Kashan, Iran; Roozmand O., Department of Computer Engineering, Shahreza Campus, University of Isfahan, Isfahan, Iran","Agent-based modelling and simulation (ABMS) is one of the topics which has been extensively studied by researchers in the field of marketing and consumer behaviour. However, no such analysis has been conducted on using Agent-based modelling and simulation in marketing and consumer behaviour. An extensive bibliometric analysis, as well as a thorough visualization and science mapping, was carried out in this field from 1995 to 2022, in response to capturing recent ABMS development in this field. A total of 1210 documents from the WOS and Scopus databases were analyse d using bibliometrix R-Tool and VOS viewer. The results showed the 20 documents with the most citations were in the area of energy consumption (55%) and innovation diffusion behaviour (20%). The USA has the most publications in this field, with the production of 188 documents. The “EXPERT SYSTEMS WITH APPLICATIONS” is a productive journal publishing in this field. Generally, the major journals that publish research on the use of ABM in marketing and consumer behaviour are multidisciplinary or interdisciplinary. 6 clusters were identified based on the analysis of the most frequent key-words: Cluster 1 (multi-agent systems and consumer behaviour), Cluster 2 (agent-based simulation and SCM), Cluster 3 (ABM and energy consumption), Cluster 4 (AMB and innovation diffusion), Cluster 5 (complex system and Simulation) and Cluster 6 (ABM and TAM). Prediction is one of the goals that has attracted the most attention of ABMS researchers among many goals such as optimization, description, self-organization, and adaptability, and there are many recent works in this field. These results show that many topics that were of interest in the past, such as the ontology of ABMS, are no longer of much interest to researchers, and the attention of researchers has been directed toward issues such as the diffusion of innovation, energy consumption, and pricing in recent years. This topic can determine the appropriate approach for other researchers to research in this field. © 2023 Qazvin Islamic Azad University. All rights reserved.","Agent-Based Modelling and Simulation; Consumer Behavior; Fuzzy; Marketing; Science Mapping","","","","","","","","Al-Alawi B. M., Bradley T. H., Review of hybrid, plug-in hybrid, and electric vehicle market modelling studies, Renewable and Sustainable Energy Reviews, 21, pp. 190-203, (2013); Al Mamun M. A., Azad M. A. 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K., Doolla S., Multiagent-based distributed-energy-resource management for intelligent microgrids, IEEE Transactions on Industrial Electronics, 60, 4, pp. 1678-1687, (2012); Peres R., Muller E., Mahajan V., Innovation diffusion and new product growth models: A critical review and research directions, International journal of research in marketing, 27, 2, pp. 91-106, (2010); Rahman T., Taghikhah F., Paul S. K., Shukla N., Agarwal R., An agent-based model for supply chain recovery in the wake of the COVID-19 pandemic, Computers & Industrial Engineering, 158, (2021); Rai V., Henry A. D., Agent-based modelling of consumer energy choices, Nature Climate Change, 6, 6, pp. 556-562, (2016); Rand W., Rust R. T., Agent-based modelling in marketing: Guidelines for rigor, International journal of research in marketing, 28, 3, pp. 181-193, (2011); Rand W., Stummer C., Agent‐based modelling of new product market diffusion: an overview of strengths and criticisms, Annals of Operations Research, 305, 1-2, pp. 425-447, (2021); Rethlefsen M. L., Kirtley S., Waffenschmidt S., Ayala A. P., Moher D., Page M. J., Koffel J. B., PRISMA-S: an extension to the PRISMA statement for reporting literature searches in systematic reviews, Systematic reviews, 10, 1, pp. 1-19, (2021); Ringler P., Keles D., Fichtner W., Agent-based modelling and simulation of smart electricity grids and markets–a literature review, Renewable and Sustainable Energy Reviews, 57, pp. 205-215, (2016); Rojas-Lamorena A. J., Del Barrio-Garcia S., Alcantara-Pilar J. M., A review of three decades of academic research on brand equity: A bibliometric approach using co-word analysis and bibliographic coupling, Journal of Business Research, 139, pp. 1067-1083, (2022); Roozmand O., Ghasem-Aghaee N., Hofstede G. J., Nematbakhsh M. A., Baraani A., Verwaart T., Agent-based modelling of consumer decision making process based on power distance and personality, Knowledge-Based Systems, 24, 7, pp. 1075-1095, (2011); Safdarian A., Fotuhi-Firuzabad M., Lehtonen M., A distributed algorithm for managing residential demand response in smart grids, IEEE Transactions on Industrial Informatics, 10, 4, pp. 2385-2393, (2014); Schwarz N., Ernst A., Agent-based modelling of the diffusion of environmental innovations—An empirical approach, Technological Forecasting and Social Change, 76, 4, pp. 497-511, (2009); Segovia J. E. T., Di Sciorio F., Mattera R., Spano M., A Bibliometric Analysis on Agent-Based Models in Finance: Identification of Community Clusters and Future Research Trends, Complexity, (2022); Sensfuss F., Ragwitz M., Genoese M., The merit-order effect: A detailed analysis of the price effect of renewable electricity generation on spot market prices in Germany, Energy policy, 36, 8, pp. 3086-3094, (2008); Shafiei E., Thorkelsson H., Asgeirsson E. I., Davidsdottir B., Raberto M., Stefansson H., An agent-based modelling approach to predict the evolution of market share of electric vehicles: A case study from Iceland, Technological Forecasting and Social Change, 79, 9, pp. 1638-1653, (2012); Sim K. M., Agent-based cloud computing, IEEE transactions on services computing, 5, 4, pp. 564-577, (2011); Van Eck N., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Yousefi S., Moghaddam M. P., Majd V. J., Optimal real time pricing in an agent-based retail market using a comprehensive demand response model, Energy, 36, 9, pp. 5716-5727, (2011); Zehra A., Urooj A., A Bibliometric Analysis of the Developments and Research Frontiers of Agent-Based Modelling in Economics, Economies, 10, 7, (2022); Zenobia B., Weber C., Daim T., Artificial markets: A review and assessment of a new venue for innovation research, Technovation, 29, 5, pp. 338-350, (2009); Zhang H., Vorobeychik Y., Empirically grounded agent-based models of innovation diffusion: a critical review, Artificial Intelligence Review, 52, pp. 707-741, (2019); Zhao J., Mazhari E., Celik N., Son Y.-J., Hybrid agent-based simulation for policy evaluation of solar power generation systems, Simulation Modelling Practice and Theory, 19, 10, pp. 2189-2205, (2011); Zhu X., Zhang Y., Co-word analysis method based on meta-path of subject knowledge network, Scientometrics, 123, 2, pp. 753-766, (2020)","Z. Sadeqi-Arani; Department of Management and Entrepreneurship, University of Kashan, Kashan, Iran; email: sadeqiarani@kashanu.ac.ir","","Qazvin Islamic Azad University","","","","","","22519904","","","","English","J. Optim. Ind. Eng.","Review","Final","","Scopus","2-s2.0-85186918230" -"Anas M.; Khan M.N.; Uddin S.M.F.","Anas, Mohammad (57217379967); Khan, Mohammed Naved (8422022500); Uddin, S.M. Fatah (57192435998)","57217379967; 8422022500; 57192435998","Mapping the concept of online purchase experience: a review and bibliometric analysis","2023","International Journal of Quality and Service Sciences","15","2","","168","189","21","4","10.1108/IJQSS-07-2022-0077","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85161471539&doi=10.1108%2fIJQSS-07-2022-0077&partnerID=40&md5=366381974591321261aefa6fb66f26bd","Department of Business Administration, Aligarh Muslim University, Aligarh, India; Department of Marketing, Birla Institute of Management Technology, Greater Noida, India","Anas M., Department of Business Administration, Aligarh Muslim University, Aligarh, India; Khan M.N., Department of Business Administration, Aligarh Muslim University, Aligarh, India; Uddin S.M.F., Department of Marketing, Birla Institute of Management Technology, Greater Noida, India","Purpose: Modern businesses strategically focus on improving the online purchase experience (OPE) of customers to acquire a long-term competitive edge. However, the intellectual knowledge structure of OPE research remains uncharted, necessitating further investigation. This study aims to provide a concise synthesis of the evolution, trends and advancements of consumers’ OPE research using bibliometrics. Design/methodology/approach: Firstly, the authors inventorised the relevant OPE literature, and then the bibliometric trends and the domain’s performance (top articles, outlets and authors) were analysed and illustrated through tables and narratives. Secondly, science mapping tools (such as co-occurrence) and visualisation strategy were deployed to pinpoint relevant OPE research themes and highlight the domain’s intellectual structure. Findings: The most significant findings concern the most prolific authors, outlets, most cited articles and five thematic clusters forming the ground for potential future research paths. Also, these thematic clusters depicted the intellectual knowledge structure that emerged from the OPE research domain. Research limitations/implications: This review may be helpful for future academic researchers to identify future research paths in the domain and practitioners to help make policy decisions while formulating and articulating their marketing strategy. Originality/value: Deploying the VOSviewer and Bibliometrix-R software together, this review is most likely the first attempt to the best of the authors’ knowledge to provide a thorough bibliometric synthesis of the OPE research domain. © 2023, Emerald Publishing Limited.","Bibliometrics; Consumer behaviour; Literature review; Online purchase experience","","","","","","","","Abbott L., Quality and Competition: An Essay in Economic Theory, (1955); Anteblian B., Filser M., Roederer C., Consumption experience in retail environments: a literature review, Recherche et Applications En Marketing (English Edition), 28, 3, pp. 82-109, (2013); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-997, (2017); Becker L., Jaakkola E., Customer experience: fundamental premises and implications for research, Journal of the Academy of Marketing Science, 48, 4, pp. 630-648, (2020); Bilgihan A., Kandampully J., Zhang T.C., Towards a unified customer experience in online shopping environments, International Journal of Quality and Service Sciences, 8, 1, pp. 102-119, (2016); 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Contrasting roles of future reward uncertainty, Journal of Business Research, 147, pp. 477-490, (2022); Yeo V.C.S., Goh S.-K., Rezaei S., Consumer experiences, attitude and behavioral intention toward online food delivery (OFD) services, Journal of Retailing and Consumer Services, 35, pp. 150-162, (2017); Yin W., Xu B., Effect of online shopping experience on customer loyalty in apparel business-to-consumer ecommerce, Textile Research Journal, 91, 23-24, pp. 2882-2895, (2021); Ylilehto M., Komulainen H., Ulkuniemi P., The critical factors shaping customer shopping experiences with innovative technologies, Baltic Journal of Management, 16, 5, pp. 661-680, (2021); Zainuldin M.H., Lui T.K., A bibliometric analysis of CSR in the banking industry: a decade study based on Scopus scientific mapping, International Journal of Bank Marketing, 40, 1, pp. 1-26, (2022); Zupic I., Cater T., Bibliometric methods in management and organisation, Organizational Research Methods, 18, 3, pp. 429-472, (2015); Patricio L., Fisk R.P., e Cunha J.F., Constantine L., Multilevel service design: from customer value constellation to service experience blueprinting, Journal of Service Research, 14, 2, pp. 180-200, (2011)","S.M.F. Uddin; Department of Marketing, Birla Institute of Management Technology, Greater Noida, India; email: smfateh87@gmail.com","","Emerald Publishing","","","","","","1756669X","","","","English","Int. J. Qual. Serv. Sci.","Review","Final","","Scopus","2-s2.0-85161471539" -"Gao C.; Wang J.; Dong S.; Liu Z.; Cui Z.; Ma N.; Zhao X.","Gao, Chao (58960787100); Wang, Jianwei (55906225000); Dong, Shi (57198546406); Liu, Zhizhen (57203092577); Cui, Zhiwei (57224798983); Ma, Ningyuan (57222374873); Zhao, Xiyang (57219384339)","58960787100; 55906225000; 57198546406; 57203092577; 57224798983; 57222374873; 57219384339","Application of Digital Twins and Building Information Modeling in the Digitization of Transportation: A Bibliometric Review","2022","Applied Sciences (Switzerland)","12","21","11203","","","","22","10.3390/app122111203","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141876578&doi=10.3390%2fapp122111203&partnerID=40&md5=c1641092bf0f64752de71a284d088f6f","College of Transportation Engineering, Chang’an University, Xi’an, 710064, China; Engineering Research Center of Highway Infrastructure Digitalization, Ministry of Education, Xi’an, 710064, China; Engineering Research Center of Digital Construction and Management for Transportation Infrastructure of Shaanxi Province, Xi’an, 710064, China; Xi’an Key Laboratory of Digitalization of Transportation Infrastructure Construction and Management, Xi’an, 710064, China; School of Economics and Management, Chang’an University, Xi’an, 710064, China","Gao C., College of Transportation Engineering, Chang’an University, Xi’an, 710064, China, Engineering Research Center of Highway Infrastructure Digitalization, Ministry of Education, Xi’an, 710064, China, Engineering Research Center of Digital Construction and Management for Transportation Infrastructure of Shaanxi Province, Xi’an, 710064, China, Xi’an Key Laboratory of Digitalization of Transportation Infrastructure Construction and Management, Xi’an, 710064, China; Wang J., College of Transportation Engineering, Chang’an University, Xi’an, 710064, China, Engineering Research Center of Highway Infrastructure Digitalization, Ministry of Education, Xi’an, 710064, China, Engineering Research Center of Digital Construction and Management for Transportation Infrastructure of Shaanxi Province, Xi’an, 710064, China, Xi’an Key Laboratory of Digitalization of Transportation Infrastructure Construction and Management, Xi’an, 710064, China; Dong S., College of Transportation Engineering, Chang’an University, Xi’an, 710064, China, Engineering Research Center of Highway Infrastructure Digitalization, Ministry of Education, Xi’an, 710064, China, Engineering Research Center of Digital Construction and Management for Transportation Infrastructure of Shaanxi Province, Xi’an, 710064, China, Xi’an Key Laboratory of Digitalization of Transportation Infrastructure Construction and Management, Xi’an, 710064, China; Liu Z., College of Transportation Engineering, Chang’an University, Xi’an, 710064, China; Cui Z., College of Transportation Engineering, Chang’an University, Xi’an, 710064, China, Engineering Research Center of Highway Infrastructure Digitalization, Ministry of Education, Xi’an, 710064, China, Engineering Research Center of Digital Construction and Management for Transportation Infrastructure of Shaanxi Province, Xi’an, 710064, China, Xi’an Key Laboratory of Digitalization of Transportation Infrastructure Construction and Management, Xi’an, 710064, China; Ma N., College of Transportation Engineering, Chang’an University, Xi’an, 710064, China; Zhao X., College of Transportation Engineering, Chang’an University, Xi’an, 710064, China, Engineering Research Center of Highway Infrastructure Digitalization, Ministry of Education, Xi’an, 710064, China, Engineering Research Center of Digital Construction and Management for Transportation Infrastructure of Shaanxi Province, Xi’an, 710064, China, School of Economics and Management, Chang’an University, Xi’an, 710064, China","The industrial transformation led by digitization-related technologies has attracted research attention in recent decades, enhancing its application in different sectors. The transport industry is a crucial driving force for economic growth and social development. It is still necessary to make transportation infrastructure and services safer, cleaner, and more affordable to cope with increasing urbanization and mobility. This paper systematically examines the science mapping of building information modeling and digital twins technologies in the digitalization of transportation. Through the bibliometric and content analysis approaches, 493 related documents were screened and analyzed from the Web of Science and Scopus databases. The software programs VOSviewer and Bibliometrix were used to determine research trends and current gaps, which will be beneficial to future research in this vital field. The results showed that over 80% of the relevant documents have been published since 2018. China is the most productive country, followed by the United States and Italy, and Germany is the most cited and influential country. Moreover, research also revealed the leading authors, top journals, and highly cited papers. The findings may be used as a guide for: (1) improving the efficiency of intelligent transportation system element management; (2) the development and application of digital technologies; (3) the flow and goals of entire-life-cycle management; and (4) the optimization of related algorithms and models. © 2022 by the authors.","applications; bibliometric analysis; building information modeling; development directions; digital twins; emerging technologies; research areas","","","","","","Postgraduates of Chang’an University, (300103722012); Transportation Science and Technology Research Project of Hebei Province, (JX-202006)","This research was funded by the Transportation Science and Technology Research Project of Hebei Province, grant number JX-202006 and the Scientific Innovation Practice Project of Postgraduates of Chang’an University, grant number 300103722012.","Costin A., Adibfar A., Hu H., Chen S.S., Building Information Modeling (BIM) for Transportation Infrastructure–Literature Review, Applications, Challenges, and Recommendations, Autom. 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Informetr, 11, pp. 959-975, (2017); Weismayer C., Pezenka I., Identifying Emerging Research Fields: A Longitudinal Latent Semantic Keyword Analysis, Scientometrics, 113, pp. 1757-1785, (2017); Jung H., Lee B.G., Research Trends in Text Mining: Semantic Network and Main Path Analysis of Selected Journals, Expert Syst. Appl, 162, (2020); Van Eck N., Waltman L., Software Survey: VOSviewer, a Computer Program for Bibliometric Mapping, Scientometrics, 84, pp. 523-538, (2010); Van Eck N.J., Waltman L., Citation-Based Clustering of Publications Using CitNetExplorer and VOSviewer, Scientometrics, 111, pp. 1053-1070, (2017); Biancardo S.A., Capano A., de Oliveira S.G., Tibaut A., Integration of BIM and Procedural Modeling Tools for Road Design, Infrastructures, 5, (2020); Biancardo S., Oreto C., Viscione N., Russo F., Ausiello G., Dell'Acqua G., Stone Pavement Analysis Using Building Information Modeling, Transp. Res. Rec, 2676, pp. 105-117, (2022); Biancardo S., Intignano M., Viscione N., De Oliveira S., Tibaut A., Procedural Modeling-Based BIM Approach for Railway Design, J. Adv. Transp, 2021, (2021); Biancardo S., Viscione N., Oreto C., Veropalumbo R., Abbondati F., BIM Approach for Modeling Airports Terminal Expansion, Infrastructures, 5, (2020); Rad M.A.H., Jalaei F., Golpour A., Varzande S.S.H., Guest G., BIM-Based Approach to Conduct Life Cycle Cost Analysis of Resilient Buildings at the Conceptual Stage, Autom. Constr, 123, (2021); Jalaei F., Zoghi M., Khoshand A., Life Cycle Environmental Impact Assessment to Manage and Optimize Construction Waste Using Building Information Modeling (BIM), Int. J. Constr. Manag, 21, pp. 784-801, (2021); Jalaei F., Jrade A., Integrating Building Information Modeling (BIM) and LEED System at the Conceptual Design Stage of Sustainable Buildings, Sustain. 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Environ, 16, pp. 429-434, (2011); Xu X., Shen B., Ding S., Srivastava G., Bilal M., Khosravi M.R., Menon V.G., Jan M.A., Wang M., Service Offloading With Deep Q-Network for Digital Twinning-Empowered Internet of Vehicles in Edge Computing, IEEE Trans. Ind. Inform, 18, pp. 1414-1423, (2022); Guo J., Bilal M., Qiu Y., Qian C., Xu X., Raymond Choo K.-K., Survey on Digital Twins for Internet of Vehicles: Fundamentals, Challenges, and Opportunities, Digit. Commun. Netw, (2022); Zhang F., Chan A.P.C., Darko A., Li D., BIM-Enabled Multi-Level Assessment of Age-Friendliness of Urban Housing Based on Multiscale Spatial Framework: Enlightenments of Housing Support for “Aging-in-Place, Sustain. Cities Soc, 72, (2021); Gao S., Ren G., Li H., Knowledge Management in Construction Health and Safety Based on Ontology Modeling, Appl. Sci, 12, (2022); Zhang G., Vela P., Karasev P., Brilakis I., A Sparsity-Inducing Optimization-Based Algorithm for Planar Patches Extraction from Noisy Point-Cloud Data, Comput.-AIDED Civ. Infrastruct. Eng, 30, pp. 85-102, (2015); Xue F., Lu W., Chen K., Automatic Generation of Semantically Rich As-Built Building Information Models Using 2D Images: A Derivative-Free Optimization Approach, Comput.-AIDED Civ. Infrastruct. Eng, 33, pp. 926-942, (2018)","J. Wang; College of Transportation Engineering, Chang’an University, Xi’an, 710064, China; email: wjianwei@chd.edu.cn","","MDPI","","","","","","20763417","","","","English","Appl. Sci.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85141876578" -"Bitar F.; Arabi M.; Bulbul Z.; Nemer G.; Jassar Y.; Bitar F.F.; Abdul Sater Z.","Bitar, Fouad (58820276800); Arabi, Mariam (23472056600); Bulbul, Ziad (6603056918); Nemer, Georges (6603311286); Jassar, Yehya (39361774400); Bitar, Fadi F. (35508040300); Abdul Sater, Zahi (55327045100)","58820276800; 23472056600; 6603056918; 6603311286; 39361774400; 35508040300; 55327045100","Congenital heart disease research landscape in the Arab world: a 25-year bibliometric review","2023","Frontiers in Cardiovascular Medicine","10","","1332291","","","","0","10.3389/fcvm.2023.1332291","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182979106&doi=10.3389%2ffcvm.2023.1332291&partnerID=40&md5=0d7015a6e8ce4718f3fcbf111bae8286","Department of Pediatrics and Adolescent Medicine, American University of Beirut-Medical Center, Beirut, Lebanon; Department of Pediatrics and Adolescent Medicine, Children’s Heart Center, American University of Beirut-Medical Center, Beirut, Lebanon; Genomics and Precision Medicine (GPM), College of Health and Life Sciences at Hamad Bin Khalifa University, Doha, Qatar; Department of Public Health, College of Public Health, Phoenicia University, Mazraat El Daoudiyeh, Lebanon; Global Health Institute, American University of Beirut, Beirut, Lebanon","Bitar F., Department of Pediatrics and Adolescent Medicine, American University of Beirut-Medical Center, Beirut, Lebanon; Arabi M., Department of Pediatrics and Adolescent Medicine, American University of Beirut-Medical Center, Beirut, Lebanon, Department of Pediatrics and Adolescent Medicine, Children’s Heart Center, American University of Beirut-Medical Center, Beirut, Lebanon; Bulbul Z., Department of Pediatrics and Adolescent Medicine, American University of Beirut-Medical Center, Beirut, Lebanon, Department of Pediatrics and Adolescent Medicine, Children’s Heart Center, American University of Beirut-Medical Center, Beirut, Lebanon; Nemer G., Genomics and Precision Medicine (GPM), College of Health and Life Sciences at Hamad Bin Khalifa University, Doha, Qatar; Jassar Y., Department of Pediatrics and Adolescent Medicine, Children’s Heart Center, American University of Beirut-Medical Center, Beirut, Lebanon; Bitar F.F., Department of Pediatrics and Adolescent Medicine, American University of Beirut-Medical Center, Beirut, Lebanon, Department of Pediatrics and Adolescent Medicine, Children’s Heart Center, American University of Beirut-Medical Center, Beirut, Lebanon; Abdul Sater Z., Department of Public Health, College of Public Health, Phoenicia University, Mazraat El Daoudiyeh, Lebanon, Global Health Institute, American University of Beirut, Beirut, Lebanon","Background: While research on congenital heart disease has been extensively conducted worldwide, comprehensive studies from developing countries and the Arab world remain scarce. Aim: This study aims to perform a bibliometric review of research on congenital heart disease in the Arab world from 1997 to 2022. Methods: We analyzed data from the Web of Science, encompassing various aspects such as topics, countries, research output, citations, authors, collaborations, and affiliations. This comprehensive science mapping analysis was done using the R statistical software's Bibliometrix Package. Results: The research output from Arab countries over the 25 years showed an average annual growth rate of 11.5%. However, Arab countries exhibited lower research productivity than the United States and Europe, with a 24-fold difference. There was substantial variation in research output among 22 Arab countries, with five countries contributing to 78% of the total publications. Most of the published research was clinical, with limited innovative contributions and a preference for regional journals. High-income Arab countries displayed higher research productivity and citation rates than their low-income developing counterparts. Despite being categorized as upper-middle-income, post-conflict countries exhibited low research productivity. About one-quarter of the published articles (26%) resulted from collaborative efforts among multiple countries, with the United States being the most frequent collaborator. Enhanced research productivity and impact output were strongly associated with increased international cooperation. Conclusion: Research productivity in the Arab region closely correlates with a country's GDP. Success hinges on governmental support, funding, international collaboration, and a clear research vision. These findings offer valuable insights for policymakers, educational institutions, and governments to strengthen research programs and nurture a research culture. 2024 Bitar, Arabi, Bulbul, Nemer, Jassar, Bitar and Abdul Sater.","Arab countries; children; congenital heart disease; developing and developed countries; limited resource countries; pediatric cardiology; research","Arab; Arab world; bibliometrics; congenital heart disease; developing country; funding; government; high income country; human; low income country; middle income country; productivity; publication; reporting bias; Review; school; systematic review (topic)","","","","","","","Liu Y., Chen S., Zuhlke L., Black G.C., Choy M., Li N., Et al., Global birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies, Int J Epidemiol, 48, 2, pp. 455-463, (2019); Murala J.S.K., Karl T.R., Pezzella A.T., Pediatric cardiac surgery in low-and middle-income countries: present status and need for a paradigm shift, Front Pediatr, 7, (2019); Van der Linde D., Konings E.E., Slager M.A., Witsenburg M., Helbing W.A., Takkenberg J.J., Et al., Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis, J Am Coll Cardiol, 58, 21, pp. 2241-2247, (2011); Dearani J.A., Neirotti R., Kohnke E.J., Sinha K.K., Cabalka A.K., Barnes R.D., Et al., Improving pediatric cardiac surgical care in developing countries: matching resources to needs, Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu, 13, 1, pp. 35-43, (2010); Jonas R.A., Congenital heart surgery in developing countries, Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu, pp. 3-6, (2008); Eken S., El-Erian M.A., Fennell S., Chauffour J.-P., Eken S., Achieving growth and stability in the Middle East and North Africa, Growth and Stability in the Middle East and North Africa, pp. 1-25, (1996); Alzyoud R., El-Kholy N., Arab Y., Choueiter N., Harahsheh A.S., Aselan A.S., Et al., Access to care and therapy for Kawasaki disease in the Arab countries: a Kawasaki disease Arab initiative (Kawarabi) multicenter survey, Pediatr Cardiol, 44, 6, pp. 1277-1284, (2023); Liang Y., Yu D., Lu Q., Zheng Y., Yang Y., The rise and fall of acute rheumatic fever and rheumatic heart disease: a mini review, Front Cardiovasc Med, 10, (2023); Chadegani A.A., Salehi H., Yunus M.M., Farhadi H., Fooladi M., Farhadi M., Et al., (2013); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, J Informetr, 11, 4, pp. 959-975, (2017); Balachandran R., Kappanayil M., Sen A.C., Sudhakar A., Nair S.G., Sunil G.S., Et al., Impact of the international quality improvement collaborative on outcomes after congenital heart surgery: a single center experience in a developing economy, Ann Card Anaesth, 18, 1, pp. 52-57, (2015); Albesher N., Massadeh S., Hassan S.M., Alaamery M., Consanguinity and congenital heart disease susceptibility: insights into rare genetic variations in Saudi Arabia, Genes (Basel), 13, 2, (2022); Nabulsi M.M., Tamim H., Sabbagh M., Obeid M.Y., Yunis K.A., Bitar F.F., Parental consanguinity and congenital heart malformations in a developing country, Am J Med Genet A, 116A, 4, pp. 342-347, (2003); Latif R., Medical and biomedical research productivity from the Kingdom of Saudi Arabia (2008–2012), J Family Community Med, 22, 1, pp. 25-30, (2015); Farhat T., Abdul-Sater Z., Obeid M., Arabi M., Diab K., Masri S., Et al., Research in congenital heart disease: a comparative bibliometric analysis between developing and developed countries, Pediatr Cardiol, 34, 2, pp. 375-382, (2013); AlBloushi A.F., Contribution of Saudi Arabia to regional and global publications on COVID-19-related research: a bibliometric and visualization analysis, J Infect Public Health, 15, 7, pp. 709-719, (2022); El Rassi I., Assy J., Arabi M., Majdalani M.N., Yunis K., Sharara R., Et al., Establishing a high-quality congenital cardiac surgery program in a developing country: lessons learned, Front Pediatr, 8, (2020); Aburawi E., Call for multinational studies of the epidemiology of congenital heart disease in the Arab world, Ibnosina J Med Biomed Sci, 5, 1, pp. 1-3, (2013); Saxena A., Status of pediatric cardiac care in developing countries, Children, 6, 2, (2019)","F.F. Bitar; Department of Pediatrics and Adolescent Medicine, American University of Beirut-Medical Center, Beirut, Lebanon; email: fbitar@aub.edu.lb; Z. Abdul Sater; Department of Public Health, College of Public Health, Phoenicia University, Mazraat El Daoudiyeh, Lebanon; email: zahi.abdulsater@pu.edu.lb","","Frontiers Media SA","","","","","","2297055X","","","","English","Front. Cardiovasc. Med.","Review","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85182979106" -"Ramanan S. S.; George A.K.; Chavan S.B.; Kumar S.; Jayasubha S.","Ramanan S., Suresh (57219195566); George, Alex K. (57208773146); Chavan, S.B. (56654882300); Kumar, Sudhir (57219195073); Jayasubha, S. (57219199674)","57219195566; 57208773146; 56654882300; 57219195073; 57219199674","Progress and future research trends on Santalum album: A bibliometric and science mapping approach","2020","Industrial Crops and Products","158","","112972","","","","23","10.1016/j.indcrop.2020.112972","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091654704&doi=10.1016%2fj.indcrop.2020.112972&partnerID=40&md5=2446061943f4c1f6cb516663f74528d7","ICAR-Central Agroforestry Research Institute, Jhansi, 284003, UP, India; University of Maine, United States; Kamaraj College of Technology, Tamil Nadu, India","Ramanan S. S., ICAR-Central Agroforestry Research Institute, Jhansi, 284003, UP, India; George A.K., University of Maine, United States; Chavan S.B., ICAR-Central Agroforestry Research Institute, Jhansi, 284003, UP, India; Kumar S., ICAR-Central Agroforestry Research Institute, Jhansi, 284003, UP, India; Jayasubha S., Kamaraj College of Technology, Tamil Nadu, India","Sandalwood (Santalum album) is woven into the culture and traditions of India for last 3000 years. However, India's dominance on the international sandalwood trade is waning. Other countries, specifically Australia are emerging as a big-mammoth player in sandalwood trade. Still, there is a high demand-supply gap for Indian Sandalwood. This offers opportunities for the countries to dominate the trade by upscaling sandalwood cultivation among farmers and various stakeholders. Considering the extent of research activity as a proxy to a country's attitude and approach towards the Santalum album, we used the theoretical framework of bibliometric studies to understand the current status of Indian sandalwood research globally. After 92 years of research (1928−2020), 374 scientific publications were listed in the Web of Science database for a single keyword search “Santalum album”. Analysis of this metadata using the bibliometrix R-package revealed an annual growth of 5.25 per cent in scientific publications over the years. Lokta's law was found to be valid for Indian sandalwood research, indicating a possibility for increased research in the upcoming years which perfectly correlate with the increase in sandalwood prices. The analysis revealed a decadal shift in prominent researching countries. India dominated in terms of the number of scientific publications for the last two decades, followed by Australia during the decade I (2000−2010). However, China surpassed Australia in the current decade (2011−2020) in terms of research output. Further, more productive researchers were from China and Australia. The increased interest of Chinese researchers can have an impact on sandalwood market in the near possible future. SciMAT science mapping tool was used to map prominent researched areas over the 92 years and to uncover the future researchable areas. The results will contribute critically to ascertaining relevant research aspects while accounting the significant gaps like field planting geometry, tree: host ratio, irrigation and nutrition management regime and yield estimation. So that complete scientific information will encourage the private cultivation and can also promote Indian sandalwood cultivation at the community level. © 2020 Elsevier B.V.","Global status; Indian sandalwood; Santalum album, research trend","Australia; China; India; Santalum; Santalum album; Mapping; Search engines; Management regime; Possible futures; Research activities; Research outputs; Scientific information; Scientific publications; Theoretical framework; Yield estimation; cultivation; metadata; stakeholder; theoretical study; upscaling; woody plant; Commerce","","","","","Central Agroforestry Research Institute","We would like to thank the Director and other scientists of the Central Agroforestry Research Institute for their encouragement and support. We also like to thank Dr. P. Krishnan, ICAR-NAARM, Hyderabad for encouragement and guidance. Sincere thanks to the reviewers for providing valuable suggestions. 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Energy, 264, (2020); Andreo-Martinez P., Ortiz-Martinez V.M., Garcia-Martinez N., Lopez P.P., Quesada-Medina J., Camara M.A., Oliva J., A descriptive bibliometric study on bioavailability of pesticides in vegetables, food or wine research (1976-2018), Environ. Toxicol. Pharmacol., (2020); Annapurna D., Rathore T.S., Joshi G., Modern nursery practices in the production of quality seedlings of Indian Sandalwood, (Santalum album L.) - Stage of host requirement and screening of primary host species, J. Sustain. For., 22, pp. 33-55, (2006); Annapurna D., Rathore T.S., Joshi G., Effect of potting medium ingredients and sieve size on the growth of seedlings of Sandalwood (Santalum album L.) in root trainers, Indian For., 133, pp. 179-188, (2007); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, J. 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Funct., 30, pp. 1983-1994, (2016); Zyoud S.H., Waring W.S., Al-Jabi S.W., Sweileh W.M., Global cocaine intoxication research trends during 1975–2015: a bibliometric analysis of Web of Science publications, Subst. Abuse Treat. Prev. Policy, 12, (2017)","S. Ramanan S.; ICAR-Central Agroforestry Research Institute, Jhansi, 284003, India; email: sureshramanan01@gmail.com","","Elsevier B.V.","","","","","","09266690","","ICRDE","","English","Ind. Crops Prod.","Article","Final","","Scopus","2-s2.0-85091654704" -"Sánchez-Núñez P.; Cobo M.J.; Vaccaro G.; Peláez J.I.; Herrera-Viedma E.","Sánchez-Núñez, Pablo (57204709743); Cobo, Manuel J. (25633455900); Vaccaro, Gustavo (57218577459); Peláez, José Ignacio (7005913080); Herrera-Viedma, Enrique (7004240703)","57204709743; 25633455900; 57218577459; 7005913080; 7004240703","Citation classics in consumer neuroscience, neuromarketing and neuroaesthetics: Identification and conceptual analysis","2021","Brain Sciences","11","5","548","","","","9","10.3390/brainsci11050548","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105520915&doi=10.3390%2fbrainsci11050548&partnerID=40&md5=77228677c638c5f4586c6fb5e93156de","Joint-PhD Programme in Communication, Department of Audiovisual Communication and Advertising, Faculty of Communication Sciences, Universidad de Málaga, Málaga, 29071, Spain; Center for Applied Social Research (CISA), Universidad de Málaga, Málaga, 29071, Spain; Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, 29010, Spain; Department of Computer Science and Engineering, School of Engineering, Universidad de Cádiz, Cádiz, 11202, Spain; Department of Languages and Computer Science, Higher Technical School of Computer Engineering, Universidad de Málaga, Málaga, 29071, Spain; Andalusian Research Institute on Data Science and Computational Intelligence, Department of Computer Science and AI, University of Granada, Granada, 18071, Spain","Sánchez-Núñez P., Joint-PhD Programme in Communication, Department of Audiovisual Communication and Advertising, Faculty of Communication Sciences, Universidad de Málaga, Málaga, 29071, Spain, Center for Applied Social Research (CISA), Universidad de Málaga, Málaga, 29071, Spain, Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, 29010, Spain; Cobo M.J., Department of Computer Science and Engineering, School of Engineering, Universidad de Cádiz, Cádiz, 11202, Spain; Vaccaro G., Center for Applied Social Research (CISA), Universidad de Málaga, Málaga, 29071, Spain, Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, 29010, Spain, Department of Languages and Computer Science, Higher Technical School of Computer Engineering, Universidad de Málaga, Málaga, 29071, Spain; Peláez J.I., Center for Applied Social Research (CISA), Universidad de Málaga, Málaga, 29071, Spain, Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, 29010, Spain, Department of Languages and Computer Science, Higher Technical School of Computer Engineering, Universidad de Málaga, Málaga, 29071, Spain; Herrera-Viedma E., Andalusian Research Institute on Data Science and Computational Intelligence, Department of Computer Science and AI, University of Granada, Granada, 18071, Spain","Neuromarketing, consumer neuroscience and neuroaesthetics are a broad research area of neuroscience with an extensive background in scientific publications. Thus, the present study aims to identify the highly cited papers (HCPs) in this research field, to deliver a summary of the academic work produced during the last decade in this area, and to show patterns, features, and trends that define the past, present, and future of this specific area of knowledge. The HCPs show a perspective of those documents that, historically, have attracted great interest from a research community and that could be considered as the basis of the research field. In this study, we retrieved 907 documents and analyzed, through H-Classics methodology, 50 HCPs identified in the Web of Science (WoS) during the period 2010–2019. The H-Classic approach offers an objective method to identify core knowledge in neuroscience disciplines such as neuromarketing, consumer neuroscience, and neuroaesthetics. To accomplish this study, we used Bibliometrix R Package and SciMAT software. This analysis provides results that give us a useful insight into the development of this field of research, revealing those scientific actors who have made the greatest contribution to its development: authors, institutions, sources, countries as well as documents and references. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.","Bibliometrix; Consumer behaviour; Consumer neuroscience; Consumer psychology; H-index; Highly cited papers (HCPs); Science mapping analysis; Scientometrics; SciMAT","article; consumer attitude; field study; human; human experiment; neuroscience; psychology; software; systematic review; Web of Science","","","","","","","Morin C., Neuromarketing: The New Science of Consumer Behavior, Society, 48, pp. 131-135, (2011); Croft J., The Challenges of Interdisciplinary Epistemology in Neuroaesthetics, Mind Brain Educ, 5, pp. 5-11, (2011); Sanchez-Fernandez J., Casado-Aranda L.-A., Bastidas-Manzano A.-B., Consumer Neuroscience Techniques in Advertising Research: A Bibliometric Citation Analysis, Sustainability, 13, (2021); Manas-Viniegra L., Nunez-Gomez P., Tur-Vines V., Neuromarketing as a strategic tool for predicting how Instagramers have an influence on the personal identity of adolescents and young people in Spain, Heliyon, 6, (2020); Khushaba R.N., Wise C., Kodagoda S., Louviere J., Kahn B.E., Townsend C., Consumer neuroscience: Assessing the brain response to marketing stimuli using electroencephalogram (EEG) and eye tracking, Expert Syst. 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No existe inflación de autores en Ciencias Sociales y Educación en España, Rev. Española Doc. Científica, 41, (2018); Baraybar-Fernandez A., Banos-Gonzalez M., Barquero-Perez O., Goya-Esteban R., Morena-Gomez A., Evaluación de las respuestas emocionales a la publicidad televisiva desde el Neuromarketing, Comun. Rev. Científica Iberoam. Comun. Y Educ, 25, pp. 19-28, (2017); Torres-Salinas D., Cabezas-Clavijo A., Jimenez-Contreras E., Altmetrics: New indicators for scientific communication in Web 2.0, Comunicar, 2013, pp. 1-9, (2015)","P. Sánchez-Núñez; Joint-PhD Programme in Communication, Department of Audiovisual Communication and Advertising, Faculty of Communication Sciences, Universidad de Málaga, Málaga, 29071, Spain; email: psancheznunez@uma.es","","MDPI AG","","","","","","20763425","","","","English","Brain Sci.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85105520915" -"Yu J.; Muñoz-Justicia J.","Yu, Jingyuan (57210829291); Muñoz-Justicia, Juan (6505709030)","57210829291; 6505709030","A bibliometric overview of twitter-related studies indexed in web of science","2020","Future Internet","12","5","91","","","","44","10.3390/FI12050091","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087081994&doi=10.3390%2fFI12050091&partnerID=40&md5=13b7e65ea669f7e866814067a25e802b","Department of Social Psychology, Universitat Autònoma de Barcelona, Barcelona, 08193, Spain","Yu J., Department of Social Psychology, Universitat Autònoma de Barcelona, Barcelona, 08193, Spain; Muñoz-Justicia J., Department of Social Psychology, Universitat Autònoma de Barcelona, Barcelona, 08193, Spain","Twitter has been one of the most popular social network sites for academic research; the main objective of this study was to update the current knowledge boundary surrounding Twitter-related investigations and, further, identify the major research topics and analyze their evolution across time. A bibliometric analysis has been applied in this article: we retrieved 19,205 Twitter-related academic articles from Web of Science after several steps of data cleaning and preparation. The R package ""Bibliometrix"" was mainly used in analyzing this content. Our study has two sections, and performance analysis contains 5 categories (Annual Scientific Production, Most Relevant Sources, Most Productive Authors, Most Cited Publications, Most Relevant Keywords.). The science mapping included country collaboration analysis and thematic analysis. We highlight our thematic analysis by splitting the whole bibliographic dataset into three temporal periods, thus a thematic evolution across time has been presented. This study is one of the most comprehensive bibliometric overview in analyzing Twitter-related studies by far. We proceed to explain how the results will benefit the understanding of current academic research interests on the social media giant. © 2020 by the authors.","Bibliometric analysis; Bibliometrix; Science mapping; Twitter","Internet; Academic research; Bibliometric analysis; Collaboration analysis; Knowledge boundaries; Performance analysis; Research topics; Social Network Sites; Thematic analysis; Social networking (online)","","","","","Universitat Autònoma de Barcelona, UAB","The APC was funded by the Department of Social Psychology, Universitat Autònoma de Barcelona. This work belongs to the framework of the doctoral programme in Person and Society in the ContemporaryWorld of the Autonomous University of Barcelona.","Twitter Annual Report 2018, (2018); Fiegerman S., Twitter Now Losing Users in the U. S; Haque U., The Reason Twitter's Losing Active Users; Twitter S., Number of Active Users 2010-2018 Statista, (2018); Ahmed W., Bath P.A., Demartini G., Chapter 4: Using Twitter as a Data Source: An Overview of Ethical, Legal, and Methodological Challenges, pp. 79-107, (2017); Kwak H., Lee C., Park H., Moon S., What is Twitter, a social network or a news media, In Proceedings of the 19th International Conference on World Wide Web-WWW '10, (2010); Gupta B.M., Kumar A., Gupta R., Dhawan S.M., A bibliometric assessment of Global Literature on ""Twitter"" during 2008-15, Int. J. Inf. Dissera. Technol, 6, pp. 199-206, (2016); Yu J., Munoz-Justicia J., Free and Low-Cost Twitter Research Software Tools for Social Science, Soc. Sci. Comput. Rev, (2020); Williams S.A., Terras M., Warwick C., What do people study when they study Twitter? Classifying Twitter related academic papers, J. Doc, 69, pp. 384-410, (2013); Kang B., Lee J.Y., A Bibliometric Analysis on Twitter Research, J. Korean Soc. Inf. Manag, 32, pp. 293-311, (2014); Pena-Lopez I., Congosto M., Aragon P., SpanishIndignadosand the evolution of the 15M movement on Twitter: Towards networked para-institutions, J. Span. Cult. Stud, 25, pp. 189-216, (2014); Isa D., Himelboim I., A Social Networks Approach to Online Social Movement: Social Mediators and Mediated Content in #FreeAJStaff Twitter Network, Soc. Media Soc, 4, (2018); Jacobson J., Mascaro C., Movember: Twitter Conversations of a Hairy Social Movement, Soc. Media Soc, (2016); Aragon P., Kappler K.E., Kaltenbrunner A., Laniado D., Volkovich Y., Communication dynamics in twitter during political campaigns: The case of the 2011 Spanish national election, Policy Internet, 5, pp. 183-206, (2013); Ceron A., D'Adda G., E-campaigning on Twitter: The effectiveness of distributive promises and negative campaign in the 2013 Italian election, New Media Soc, 28, pp. 1935-1955, (2016); Jaharudin M.H., The 13th General Elections: Changes in Malaysian Political Culture and Barsian Nasional's Crisis of Moral Legitimacy, Kaji Malays, 32, pp. 149-169, (2014); Hernandez-Suarez A., Sanchez-Perez G., Toscano-Medina L.K., Perez-Meana H.M., Portillo-Portillo J., Villalba L.J.G., Villalba L.J.G., Using Twitter Data to Monitor Natural Disaster Social Dynamics: A Recurrent Neural Network Approach with Word Embeddings and Kernel Density Estimation, Sensors, 29, (2019); Gutierrez C., Figuerias P., Oliveira P., Costa R., Jardim-Goncalves R., Twitter mining for traffic events detection, In Proceedings of the 2015 Science and Information Conference, pp. 371-378, (2015); Wang L., Gan J.Q., Prediction of the 2017 French Election Based on Twitter Data Analysis, In Proceedings of the 2017 9th Computer Science and Electronic Engineering (CEEC), (2017); Bollen J., Mao H., Zeng X.-J., Twitter mood predicts the stock market, J. Comput. Sci, 2, pp. 1-8, (2011); Zimmer M., Proferes N., A topology of Twitter research: Disciplines, methods, and ethics, Aslib J. Inf. Manag, 66, pp. 250-261, (2014); Weller K., What do we get from Twitter-and What Not? A Close Look at Twitter Research in the Social Sciences, Knowl. Organ, 42, pp. 238-248, (2014); Williams S.A., Terras M., Warwick C., McGowan B., Pedrana A., How Twitter Is Studied in the Medical Professions: A Classification of Twitter Papers Indexed in PubMed, Med. 2.0, 2, (2013); van Raan A.F.J., The use of bibliometric analysis in research performance assessment and monitoring of interdisciplinary scientific developments, Tech. Theor. Prax, 2, pp. 20-29, (2003); Broadus R.N., Toward a definition of ""bibliometrics, Scientometrics, 22, pp. 373-379, (1987); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Inf, 22, pp. 959-975, (2017); Noyons E.C.M., Moed H.F., Luwel M., Combining mapping and citation analysis for evaluative bibliometric purposes: A bibliometric study, J. Am. Soc. Inf. Sci, 50, pp. 115-131, (1999); van Raan A.F.J., Measuring Science, Handbook of Quantitative Science and Technology Research, pp. 19-50, (2005); van Raan A.F.J., Measurement of Central Aspects of Scientific Research: Performance, Interdisciplinarity, Structure, Meas. Interdiscip. Res. Perspect, 3, pp. 1-19, (2005); Gutierrez-Salcedo M., Martinez M.A., Moral-Munoz J.A., Herrera F., Cobo M.J., Some bibliometric procedures for analyzing and evaluating research fields, Appl. Intell, 48, pp. 1275-1287, (2017); Borner K., Chen C., Boyack K., Visualizing knowledge domains, Annu. Rev. Inf. Sci. Technol, 37, pp. 179-255, (2005); Callon M., Courtial J.P., Laville F., Co-word analysis as a tool for describing the network of interactions between basic and technological research: The case of polymer chemsitry, Scientometrics, 22, pp. 155-205, (1991); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: A practical application to the Fuzzy Sets Theory field, J. Inf, 5, pp. 146-166, (2011); Cobo M.J., Herrera-Viedma E., Herrera F., Lopez-Herrera A., SciMAT: A new science mapping analysis software tool, J. Am. Soc. Inf. Sci. Technol, 63, pp. 1609-1630, (2012); Leopold E., May M., Paass G., Data Mining and Text Mining for Science & Technology Research, Handbook of Quantitative Science and Technology Research, pp. 187-213, (2004); van Eck N.J., Waltman L., How to normalize cooccurrence data? An analysis of some well-known similarity measures, J. Am. Soc. Inf. Sci. Technol, 60, pp. 1635-1651, (2009); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, pp. 523-538, (2009); Waltman L., van Eck N.J., Noyons E., A unified approach to mapping and clustering of bibliometric networks, J. Inf, 4, pp. 629-635, (2010); Wang M., Chai L., Three new bibliometric indicators/approaches derived from keyword analysis, Scientometrics, 116, pp. 721-750, (2018); Waila P., Singh V.K., Singh M.K., A Scientometric Analysis of Research in Recommender Systems, J. Sci. Res, 5, pp. 71-84, (2016); Sweileh W., Al-Jabi S.W., AbuTaha A.S., Zyoud S., Anayah F.M.A., Sawalha A.F., Bibliometric analysis of worldwide scientific literature in mobile-health: 2006-2016, BMC Med. Inform. Decis. Mak, 17, (2017); Thelwall M., Author gender differences in psychology citation impact 1996-2018, Int. J. Psychol, (2019); Clarivate Analytics KeyWords Plus Generation, Creation, and Changes, (2020); Zhang J., Yu Q., Zheng F., Long C., Lu Z., Duan Z., Comparing keywords plus of WOS and author keywords: A case study of patient adherence research, J. Assoc. Inf. Sci. Technol, 67, pp. 967-972, (2015); van Eck N.J., Waltman L., BIBLIOMETRIC MAPPING OF THE COMPUTATIONAL INTELLIGENCE FIELD, Int. J. Uncertain. Fuzziness Knowl. Based Syst, 15, pp. 625-645, (2007); Newman M.E.J., Girvan M., Finding and evaluating community structure in networks, Phys. Rev. E, 69, (2004); Liao H., Tang M., Luo L., Li C., Chiclana F., Zeng X.-J., A Bibliometric Analysis and Visualization of Medical Big Data Research, Sustainability, 10, (2018); Holmberg K., Thelwall M., Disciplinary differences in Twitter scholarly communication, Scientometrics, 101, pp. 1027-1042, (2014); Thelwall M., Haustein S., Lariviere V., Sugimoto C.R., Do Altmetrics Work, Twitter and Ten Other Social Web Services. PLoS ONE, 8, (2013); Buccafurri F., Lax G., Nicolazzo S., Nocera A., Comparing Twitter and Facebook user behavior: Privacy and other aspects, Comput. Hum. Behav, 52, pp. 87-95, (2015); Lu X., Brelsford C., Network Structure and Community Evolution on Twitter: Human Behavior Change in Response to the 2011 Japanese Earthquake and Tsunami, Sci. Rep, 4, (2014); Chatfield A., Scholl H.J., Brajawidagda U., Tsunami early warnings via Twitter in government: Net-savvy citizens' co-production of time-critical public information services, Gov. Inf. Q, 30, pp. 377-386, (2013); Fung I.C.-H., Tse Z.T.H., Cheung C.-N., Miu A.S., Fu K.-W., Ebola and the social media, Lancet, 384, (2014); Atzori L., Iera A., Morabito G., Nitti M., The Social Internet of Things (SIoT)-When social networks meet the Internet of Things: Concept, architecture and network characterization, Comput. Netw, 56, pp. 3594-3608, (2012); Das D., Chidananda H.T., Sahoo L., Personalized movie recommendation system using twitter data, Progress in Computing, Analytics and Networking. Advances in Intelligent Systems and Computing, 710, pp. 339-347, (2018); Fausto S., Aventurier P., Scientific Literature on Twitter as a Subject Research: Findings Based on Bibliometric Analysis, Handbook Twitter For Research 2015-2016, (2016)","J. Yu; Department of Social Psychology, Universitat Autònoma de Barcelona, Barcelona, 08193, Spain; email: jingyuan.yu@e-campus.uab.cat","","MDPI AG","","","","","","19995903","","","","English","Future Internet","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85087081994" -"Mishra M.; Sudarsan D.; Santos C.A.G.; Mishra S.K.; Kar D.; Baral K.; Pattnaik N.","Mishra, Manoranjan (57835238600); Sudarsan, Desul (57204874589); Santos, Celso Augusto Guimarães (7201458646); Mishra, Shailendra Kumar (35741271700); Kar, Dipika (57217055561); Baral, Kabita (57221519125); Pattnaik, Namita (57203009859)","57835238600; 57204874589; 7201458646; 35741271700; 57217055561; 57221519125; 57203009859","An overview of research on natural resources and indigenous communities: a bibliometric analysis based on Scopus database (1979–2020)","2021","Environmental Monitoring and Assessment","193","2","59","","","","67","10.1007/s10661-020-08793-2","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099342153&doi=10.1007%2fs10661-020-08793-2&partnerID=40&md5=2208878e3f2fc853d70d76f5776e0b75","Department of Natural Resources Management and Geo-informatics, Khallikote University, Berhampur, 768003, Odisha, India; Department of Library and Information Science, Khallikote University, Berhampur, India; Department of Civil and Environmental Engineering, Federal University of Paraíba, João Pessoa, 58051-900, Brazil; Department of Anthropology, University of Allahabad, Allahabad, 211002, India; Department of Geography, Government Autonomous College Anugul, Odisha, India","Mishra M., Department of Natural Resources Management and Geo-informatics, Khallikote University, Berhampur, 768003, Odisha, India; Sudarsan D., Department of Library and Information Science, Khallikote University, Berhampur, India; Santos C.A.G., Department of Civil and Environmental Engineering, Federal University of Paraíba, João Pessoa, 58051-900, Brazil; Mishra S.K., Department of Anthropology, University of Allahabad, Allahabad, 211002, India; Kar D., Department of Natural Resources Management and Geo-informatics, Khallikote University, Berhampur, 768003, Odisha, India; Baral K., Department of Natural Resources Management and Geo-informatics, Khallikote University, Berhampur, 768003, Odisha, India; Pattnaik N., Department of Geography, Government Autonomous College Anugul, Odisha, India","Indigenous people constitute an important section of society in many countries. Despite being a numerically smaller section, they are culturally diverse and distributed mostly in valuable natural resources-rich regions worldwide. In the era of globalization, industrialization, and trade liberalization, indigenous communities have become more vulnerable to displacement, land alienation, cultural erosion, and social exclusion. During the last few decades, researchers have tried to evaluate and document their problems and prospects. The present study analyzes the trends and characteristics of research and development conducted about indigenous communities. The research hotspots based on keywords, productive researchers, and journals during 1979–2020 were mapped using the Scopus database. The analysis was carried out using the bibliometrix R-package and VOSviewer software tool. Consistent growth in the number of studies and citations on indigenous communities concerning environmental conservation, natural resources, and economic development was observed during the last four decades. The present findings reveal that research on the indigenous community has attracted the attention of the scientific community in recent years. Qualitative studies with methodological rigor, having potential for social and policy implications, are warranted to understand and respect ingrained cultural and socio-economic diversity among these communities. [Figure not available: see fulltext.] © 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG part of Springer Nature.","Bibliographic databases; Cocitation; Science mapping; Scientometrics; VOSviewer; Workflow","Bibliometrics; Databases, Factual; Environmental Monitoring; Humans; Natural Resources; Population Groups; Scopus; Conservation; Database systems; International trade; Natural resources; Public policy; Bibliographic database; Bibliometrics analysis; Cocitation; Indigenous community; Indigenous people; Science mapping; Scientometrics; Scopus database; Vosviewer; Work-flows; cultural geography; database; indigenous population; literature review; natural resource; policy approach; research work; social exclusion; socioeconomic status; bibliometrics; environmental monitoring; factual database; human; natural resource; population group; Information services","","","","","Aruna Asaf Ali Marg, (IMPRESS/P876/39/18-19/ICSSR); Ministry of Human Resource Development/Indian Council of Social Science Research; Indian Council of Social Science Research, ICSSR, (IMPRESS/P876/39/18-19); Indian Council of Social Science Research, ICSSR","This study was financed by the Ministry of Human Resource Development/Indian Council of Social Science Research, Aruna Asaf Ali Marg, New Delhi 110067, under the scheme of Impactful Policy Research in Social Science with grant number IMPRESS/P876/39/18-19/ICSSR Project. ","Anderson M.K., Tending the Wild: Native American Knowledge and the Management of California’s Natural Resources, (2005); Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Baier-fuentes H., Merigo J.M., Amoros J.E., Gaviria-marin M., International entrepreneurship: a bibliometric overview, International Entrepreneurship and Management Journal, 15, 2, pp. 385-429, (2019); Callon M., Courtial J.-P., Turner W.A., Bauin S., From translations to problematic networks: an introduction to co-word analysis, Social Science Information, 22, 2, pp. 191-235, (1983); Castro A.P., Nielsen E., Indigenous people and co-management: implications for conflict management, Environmental Science & Policy, 4, 4-5, pp. 229-239, (2001); Chapin M., Lamb Z., Threlkeld B., Mapping indigenous lands, Annual Review of Anthropology, 34, pp. 619-638, (2005); Chen C., The CiteSpace Manual v1.05, College of Computing and Informatics, (2015); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science mapping software tools: review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., SciMAT: a new science mapping analysis software tool, Journal of the American Society for Information Science and Technology, 63, 8, pp. 1609-1630, (2012); Commander S., Industrialization and sectoral imbalance: coal mining and the theory of dualism in colonial and independent India, The Journal of Peasant Studies, 9, 1, pp. 86-96, (1981); Cox P.A., Will tribal knowledge survive the millennium?, Science, 287, 5450, pp. 44-45, (2000); Deloria V.J., Native Americans: the American Indian Today, The Annals of the American Academy of Political and Social Science, 454, 1, pp. 139-149, (1981); Ding H., Veit P., Blackman A., Gray E., Reytar K., Altamirano J.C., Hodgdon B., Climate benefits, tenure costs: the economic case for securing indigenous land rights in the amazon, (2016); van Eck N.J., Waltman L., Text Mining and Visualization Using Vosviewer, (2011); Finer M., Jenkins C.N., Pimm S.L., Keane B., Ross C., Oil and gas projects in the Western Amazon: threats to wilderness, biodiversity, and indigenous peoples, PLoS ONE, 3, 8, (2008); Gadgil M., Berkes F., Folke C., Indigenous knowledge for biodiversity conservation, Ambio, 22, 2-3, pp. 151-156, (1993); Godoy R., Reyes-Garcia V., Byron E., Leonard W.R., Vadez V., The effect of market economies on the well-being of indigenous peoples and on their use of renewable natural resources, Annual Review of Anthropology, 34, pp. 121-138, (2005); Hood W.W., Wilson C.S., The literature of bibliometrics, and informetrics scientometrics, Scientometrics, 52, 2, pp. 291-314, (2001); Jacquelin-Andersen P., The Indigenous World 2018, (2018); Kessler M.M., Bibliographic coupling between scientific papers, American Documentation, 14, 1, pp. 10-25, (1963); Koocheki A.A., Indigenous knowledge in agriculture with particular reference to saffron production in Iran, I International Symposium on Saffron Biology and Biotechnology, 650, pp. 175-182, (2003); Koseoglu M.A., Growth and structure of authorship and co-authorship network in the strategic management realm: evidence from the Strategic Management Journal, BRQ Business Research Quarterly, 19, 3, pp. 153-170, (2016); Lawler J.J., Lewis D.J., Nelson E., Plantinga A.J., Polasky S., Withey J.C., Helmers D.P., Martinuzzi S., Pennington D., Radeloff V.C., Projected land-use change impacts on ecosystem services in the United States, Proceedings of the National Academy of Sciences of the United States of America, 111, 20, pp. 7492-7497, (2014); Lockwood M., Good governance for terrestrial protected areas: A framework, principles and performance outcomes, Journal of Environmental Management, 91, 3, pp. 754-766, (2010); Mantyka-Pringle C.S., Jardine T.D., Bradford L., Bharadwaj L., Kythreotis A.P., Fresque-Baxter J., Et al., Bridging science and traditional knowledge to assess cumulative impacts of stressors on ecosystem health, Environment International, 102, pp. 125-137, (2017); Menzies C.R., Traditional Ecological Knowledge and Natural Resource Management, (2006); Merigo J.M., Pedrycz W., Weber R., de la Sotta C., Fifty years of information sciences: a bibliometric overview, Information Sciences, 432, pp. 245-268, (2018); Mishra M., Sudarsan D., Kar D., Naik A.K., Das P.P., Santos C.A.G., Silva R.M., The development and research trend of using DSAS tool for shoreline change analysis: a scientometric analysis, Journal of Urban and Environmental Engineering, 14, 1, pp. 69-77, (2020); Mowat H., Veit P., The IPCC Calls for Securing Community Land Rights to Fight Climate Change, (2019); Notess L., Veit P.G., Monterroso I., Sulle E., Larson A.M., Gindroz A.S., Et al., The scramble for land rights: Reducing inequity between communities and companies, (2018); Persson O., Danell R., Schneider J.W., How to use Bibexcel for various types of bibliometric analysis, Celebrating Scholarly Communication Studies: A Festschrift for Olle Persson at His 60Th Birthday, 5, (2009); Peters H.P.F., Van Raan A.F.J., Structuring scientific activities by co-author analysis, Scientometrics, 20, 1, pp. 235-255, (1991); Pierotti R., Wildcat D., Traditional ecological knowledge: the third alternative (commentary), Ecological Applications, 10, 5, pp. 1333-1340, (2000); Pierotti R., Wildcat D.R., Finding the indigenous in indigenous studies, Indigenous Nations Studies Journal, 1, 1, pp. 61-70, (2000); Pritchard A., Statistical bibliography or bibliometrics, Journal of Documentation, 25, 4, pp. 348-349, (1969); Reytar K., Veit P., 5 maps show how important indigenous peoples and local communities are to the environment, (2017); Who owns the world’s land? A global baseline of formally recognized indigenous and community land rights, (2015); Ruffing L.T., The Navajo Nation: a history of dependence and underdevelopment, Review of Radical Political Economics, 11, 2, pp. 25-43, (1979); Sangha K., Duvert A., Archer R., Russell-Smith J., Unrealised economic opportunities in remote indigenous communities: Case studies from Northern Australia, SSRN Electronic Journal, (2020); Small H., Co-citation in the scientific literature: a new measure of the relationship between two documents, Journal of the American Society for Information Science, 24, 4, pp. 265-269, (1973); Van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Whyte K.P., Justice forward: Tribes, climate adaptation and responsibility, In Climate Change and Indigenous Peoples in the United States, pp. 9-22, (2013); Indigenous Peoples, (2019)","C.A.G. Santos; Department of Civil and Environmental Engineering, Federal University of Paraíba, João Pessoa, 58051-900, Brazil; email: celso@ct.ufpb.br","","Springer Science and Business Media Deutschland GmbH","","","","","","01676369","","EMASD","33442808","English","Environ. Monit. Assess.","Review","Final","","Scopus","2-s2.0-85099342153" -"Murillo-Vargas G.; Gonzalez-Campo C.H.; Brath D.I.","Murillo-Vargas, Guillermo (35322713400); Gonzalez-Campo, Carlos Hernan (37074466800); Brath, Diony Ico (57222987102)","35322713400; 37074466800; 57222987102","Mapping the Integration of the Sustainable Development Goals in Universities: Is It a Field of Study","2020","Journal of Teacher Education for Sustainability","22","2","","7","25","18","28","10.2478/jtes-2020-0013","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104328442&doi=10.2478%2fjtes-2020-0013&partnerID=40&md5=f2c419402ffbd2c00d0a555820b47394","Administration and Organizations Department, Universidad Del Valle, Sede San Fernando, Calle 4b 36-00 edif. 124 of. 3009, Cali, Colombia","Murillo-Vargas G., Administration and Organizations Department, Universidad Del Valle, Sede San Fernando, Calle 4b 36-00 edif. 124 of. 3009, Cali, Colombia; Gonzalez-Campo C.H., Administration and Organizations Department, Universidad Del Valle, Sede San Fernando, Calle 4b 36-00 edif. 124 of. 3009, Cali, Colombia; Brath D.I., Administration and Organizations Department, Universidad Del Valle, Sede San Fernando, Calle 4b 36-00 edif. 124 of. 3009, Cali, Colombia","This article maps the scientific production and the contents associated with the sustainable development goals and their integration with universities during the past 21 years. Although many ofthe topics related to sustainable development goals (SDGs) have been addressed in different studiesfor decades, it is since 2015 onwards that they gained greater prominence due to the inclusion of higher education as an important actor in the fulfillment of the 2030 agenda and the United Nations SDGs. For the purpose of this paper, a bibliometric analysis of 871 papers, 535 documents in Scopus, and 336 in Web of Science (WoS) from 1998 to 2019 was performed, and the Bibliometrix analysis tool was used. The objective of this mapping is to answer the following research question: Is the integration of the Sustainable Development Goals and Universities a field of study An analysis of thenetwork of collaborators and trend topics in Scopus and WoS allows us to identify the concurrence and relationships of some keywords, such as sustainable development, sustainability and planning, and some background words, such as humans and global health. In another analysis, the word ""higher education""is related to change. This article suggests that the integration of the Sustainable Development Goals in Universities is becoming a field of study under exploration, with a peak of production in 2016 and that has remained stable in the last three years, but thanks to the leading role assigned to Universities, intellectual production should increase in the following years. © 2020 Guillermo Murillo-Vargas et al., published by Sciendo.","higher education; objectives; science mapping; sustainable development; universities","","","","","","","","","G. Murillo-Vargas; Administration and Organizations Department, Universidad del Valle, Sede San Fernando, Cali, Calle 4b 36-00 edif. 124 of. 3009, Colombia; email: guillermo.murillo@correounivalle.edu.co","","Sciendo","","","","","","16914147","","","","English","J. Teach. Educ. Sustainability","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85104328442" -"Silva D.G.; Cachinho H.; Ward K.","Silva, Diogo Gaspar (57211140491); Cachinho, Herculano (55487203400); Ward, Kevin (7201457593)","57211140491; 55487203400; 7201457593","Science Mapping the Academic Knowledge on Business Improvement Districts","2022","Computation","10","2","29","","","","8","10.3390/computation10020029","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85124902855&doi=10.3390%2fcomputation10020029&partnerID=40&md5=2fa3f8e50ddd4b94833acece9d001316","Centre for Geographical Studies, Institute of Geography and Spatial Planning, University of Lisbon, Lisbon, 1600-276, Portugal; Department of Geography/Manchester Urban Institute, The University of Manchester, Manchester, M13 9PL, United Kingdom","Silva D.G., Centre for Geographical Studies, Institute of Geography and Spatial Planning, University of Lisbon, Lisbon, 1600-276, Portugal; Cachinho H., Centre for Geographical Studies, Institute of Geography and Spatial Planning, University of Lisbon, Lisbon, 1600-276, Portugal; Ward K., Department of Geography/Manchester Urban Institute, The University of Manchester, Manchester, M13 9PL, United Kingdom","Business Improvement Districts (BIDs) are a contemporary urban revitalization policy that has been set in motion through international policymaking circuits. They have been presented as a panacea to the economic and social challenges facing many cities and traditional shopping districts. However, a comprehensive overview of the academic literature on this form of local governance remains to be conducted. Drawing on bibliometric methods and bibliometrix R-tool, this paper maps and examines the state-of-the-art of academic knowledge on BIDs published between 1979 and 2021. Findings suggest that (i) scientific production has increased since the early 2000s, has crossed US borders but remains highly Anglo-Saxon-centered; (ii) academic knowledge on BIDs is multidisciplinary and has been published in high-impact journals; (iii) influential documents on BIDs have centered on three issues: urban governance/politics, policy mobilities–mutation and impacts assessment and criticisms; (iv) while author collaboration networks exist, the interaction between them is limited; (v) the conceptualization of BIDs has changed over time, both in thematic and geographical focus. These results constitute the first science mapping on the academic literature on BIDs, and we argue they should inform future scientific debates about the studying of this form of local governance. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.","Bibliometric analysis; Bibliometrics; Business improvement districts; Mobile policy; Science mapping; Systematic literature review; Urban governance; Urban policy; Urban revitalization","","","","","","Fundação para a Ciência e a Tecnologia, FCT, (PTDC/GES-URB/31878/2017, 2020.06080.BD, 2020.06080)","Funding text 1: This research was funded by Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia, I.P., grant number 2020.06080.BD, and PTDC/GES-URB/31878/2017 (PHOENIX\u2014Retail-Led Urban Regeneration and the New Forms of Governance).; Funding text 2: Funding: This research was funded by Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia, I.P., grant number 2020.06080.BD, and PTDC/GES-URB/31878/2017 (PHOENIX\u2014Retail-Led Urban Regeneration and the New Forms of Governance).","Delany S.R., Times Square Red, Times Square Blue, (1999); McNamara R.P., Sex, Scams, and Street Life: The Sociology of New York City’s Times Square, (1995); Sagalyn L.B., Times Square Roulette: Remaking the City Icon, (2003); Radywyl N., Biggs C., Reclaiming the commons for urban transformation, J. Clean. Prod, 50, pp. 159-170, (2013); Ward K., Business Improvement Districts: Policy Origins, Mobile Policies and Urban Liveability, Geogr. Compass, 1, pp. 657-672, (2007); Peyroux E., Putz R., Glasze G., Business Improvement Districts (BIDs): The internationalization and contextualization of a ‘travelling concept’, Eur. Urban Reg. Stud, 19, pp. 111-120, (2012); Devlin R.T., ‘An area that governs itself’: Informality, uncertainty and the management of street vending in New York City, Plan. Theory, 10, pp. 53-65, (2011); Ellen I.G., Schwartz A.E., Voicu I., Brooks L., Hoyt L., The Impact of Business Improvement Districts on Property Values: Evidence from New York City [with Comments], pp. 1-39, (2007); Sutton S.A., Are BIDs Good for Business? The Impact of BIDs on Neighborhood Retailers in New York City, J. Plan. Educ. Res, 34, pp. 309-324, (2014); Lydon M., Garcia A., Tactical Urbanism: Short-term Action for Long-term Change, (2015); Blake O., Glaser M., Bertolini L., te Brommelstroet M., How policies become best practices: A case study of best practice making in an EU knowledge sharing project, Eur. Plan. Stud, 29, pp. 1251-1271, (2021); Hoyt L., Importing Ideas: The Transnational Transfer of Urban Revitalization Policy, Int. J. Public Adm, 29, pp. 221-243, (2006); Michel B., Stein C., Reclaiming the European City and Lobbying for Privilege: Business Improvement Districts in Germany, Urban Aff. Rev, 51, pp. 74-98, (2014); Richner M., Olesen K., Towards business improvement districts in Denmark: Translating a neoliberal urban intervention model into the Nordic context, Eur. Urban Reg. Stud, 26, pp. 158-170, (2018); Valli C., Hammami F., Introducing Business Improvement Districts (BIDs) in Sweden: A social justice appraisal, Eur. Urban Reg. Stud, 28, pp. 155-172, (2020); De Oliveira O., Silva F.F., Juliani F., Barbosa L.C., Nunhes T., Bibliometric method for mapping the state-of-the-art and identifying research gaps and trends in literature: An essential instrument to support the development of scientific projects, Scientometrics Recent Advances, pp. 1-20, (2019); Zupic I., Cater T., Bibliometric Methods in Management and Organization, Organ Res. Methods, 18, pp. 429-472, (2014); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr, 11, pp. 959-975, (2017); Ward K., Entrepreneurial Urbanism and Business Improvement Districts in the State of Wisconsin: A Cosmopolitan Critique, Ann. Assoc. Am. Geogr, 100, pp. 1177-1196, (2010); Charenko M., A historical assessment of the world’s first Business Improvement Area (BIA): The case of Toronto’s Bloor West Village, Can. J. Urban. Res, 24, pp. 1-19, (2015); Hernandez J., Jones K., The strategic evolution of the BID model in Canada, Business Improvement Districts—Research, Theories, and Controversies, pp. 401-421, (2008); Mitchell J., Business Improvement Districts and the “New” Revitalization of Downtown, Econ. Dev. Q, 15, pp. 115-123, (2001); Becker C., Democratic Accountability and Business Improvement Districts, Public Perform. Manag. Rev, 36, pp. 187-202, (2012); Mallett W., Managing the Post-Industrial City: Business Improvement Districts in the United States, Area, 26, pp. 276-287, (1994); Briffault R., A Government for Our Time? Business Improvement Districts and Urban Governance, Columbia Law Rev, 99, pp. 365-477, (1999); Levy P.R., Paying for the Public Life, Econ. Dev. Q, 15, pp. 124-131, (2001); Elstein A., Shaping a Neighborhood’s Destiny from the Shadows, Crain’s New York Business, (2016); Cook I., Mobilising Urban Policies: The Policy Transfer of US Business Improvement Districts to England and Wales, Urban Stud, 45, pp. 773-795, (2008); Eick V., The co-production of purified space: Hybrid policing in German Business Improvement Districts, Eur. Urban Reg. Stud, 19, pp. 121-136, (2012); Grail J., Mitton C., Ntounis N., Parker C., Quin S., Steadman C., Warnaby G., Cotterill E., Smith D., Business improvement districts in the UK: A review and synthesis, J. Place Manag. Dev, 13, pp. 73-88, (2020); Melik R., van der Krabben E., Co-production of public space: Policy translations from New York City to the Netherlands, Town Plan Rev, 87, pp. 139-158, (2016); Yasui M., Challenges in district management in Japanese City centres: Establishing independent business models using local resources, J. Urban Regen. Renew, 6, pp. 264-277, (2013); Radosavljevic U., Djordjevic A., Business improvement districts as a management instrument for city center’s regeneration in Serbia, Facta Univ. Archit. Civ. Eng, 13, pp. 11-22, (2015); Prifti R., Jaupi F., Entrepreneurial Urban Regeneration: Business Improvement Districts as a Form of Organizational Innovation, (2021); Brettmo A., Browne M., Business Improvement Districts as important influencers for changing to sustainable urban freight, Cities, 97, (2020); Ward K., Policies in Motion’, Urban Management and State Restructuring: The Trans-Local Expansion of Business Improvement Districts, Int. J. Urban Reg. Res, 30, pp. 54-75, (2006); Hoyt L., Gopal-Agge D., The Business Improvement District Model: A Balanced Review of Contemporary Debates, Geogr. Compass, 1, pp. 946-958, (2007); Ward K., Cook I., Business improvement districts in the United Kingdom, Territorial Policy and Governance: Alternative Paths, pp. 125-146, (2017); Morcol G., Wolf J.F., Understanding Business Improvement Districts: A New Governance Framework, Public Adm. Rev, 70, pp. 906-913, (2010); Silva D.G., Cachinho H., Places of Phygital Shopping Experiences? The New Supply Frontier of Business Improvement Districts in the Digital Age, Sustainability, 13, (2021); Broadus R.N., Toward a Definition of “Bibliometrics”, Scientometrics, 5, pp. 373-379, (1987); Chen C., Science Mapping: A Systematic Review of the Literature, J. Data Inf. Sci, 2, pp. 1-40, (2017); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science Mapping Software Tools: Review, Analysis, and Cooperative Study Among Tools, J. Assoc. Inf. Sci. Technol, 62, pp. 1382-1402, (2011); Norris M., Oppenheim C., Comparing alternatives to the Web of Science for coverage of the social sciences’ literature, J. Informetr, 1, pp. 161-169, (2007); Waltman L., A review of the literature on citation impact indicators, J. Informetr, 10, pp. 365-391, (2016); Mongeon P., Paul-Hus A., The journal coverage of Web of Science and Scopus: A comparative analysis, Scientometrics, 46, pp. 575-589, (2016); Marsh H.W., Jayasinghe U.W., Bond N.W., Improving the peer-review process for grant applications: Reliability, validity, bias, and generalizability, Am. Psychol, 63, pp. 160-168, (2008); Spall S., Peer Debriefing in Qualitative Research: Emerging Operational Models, Qual. Inq, 4, pp. 280-292, (1998); Grunsky E.C., R: A data analysis and statistical programming environment—An emerging tool for the geosciences, Comput. Geosci, 10, pp. 1219-1222, (2002); Bornmann L., Daniel H.D., What do citation counts measure? A review of studies on citing behavior, J. Doc, 64, pp. 45-80, (2008); Sparkes A.C., Making a Spectacle of Oneself in the Academy Using the H-Index: From Becoming an Artificial Person to Laughing at Absurdities, Qual. Inq, 27, pp. 1027-1039, (2021); Spooner M., Qualititave research and global audit culture: The politics of productivity, accountability, and possibility, The SAGE Handbook of Qualitative Research, pp. 894-914, (2018); Hirsch J.E., An index to quantify an individual’s scientific research output, Proc. Natl. Acad. Sci. USA, 102, pp. 16569-16572, (2005); White H.D., McCain K.W., Visualizing a Discipline: An Author Co-Citation Analysis of Information Science, 1972–1995, J. Am. Soc. Inf. Sci, 49, pp. 327-355, (1998); Jeong Y.K., Song M., Ding Y., Content-based author co-citation analysis, J. Informetr, 8, pp. 197-211, (2014); Glanzel W., National characteristics in international scientific co-authorship relations, Scientometrics, 51, pp. 69-115, (2001); Fonseca B., Sampaio R., Fonseca M., Zicker F., Co-authorship network analysis in health research: Method and potential use, Health Res. Policy Syst, 14, pp. 1-10, (2016); Sedighi M., Application of word co-occurrence analysis method in mapping of the scientific fields (case study: The field of Informetrics), Libr. Rev, 65, pp. 52-64, (2016); Stevenson M.A., Case Studies of Ontario’s Business Improvement Area Program: Toronto, Oshawa, Acton and Welland, (1979); Galt G., Perth revival (Ontario), Can. Geogr. Index, 104, pp. 34-43, (1984); Schmidt G., Gravelle J., Downtown revitalization in Ontario: Is the effort and cost worth the result?, Pap. Can. Econ. Dev, 4, pp. 51-58, (1993); Mallett W., Private Government Formation in the DC Metropolitan Area, Growth Change, 24, pp. 385-415, (1993); Lavery K., Privatization by the back door: The rise of private government in the USA, Pub. Money Manage, 15, pp. 49-53, (1995); Houstoun L.O., Smart money: New directions for business improvement districts, Planning, 64, pp. 12-15, (1998); Lloyd M.G., McCarthy J., McGreal S., Berry J.I.M., Business Improvement Districts, Planning and Urban Regeneration, Int. Plann. Stud, 8, pp. 295-321, (2003); Jones P., Hillier D., Comfort D., Business improvement districts in town and city centres in the UK, Manag. Res. News, 26, pp. 50-59, (2003); Peel D., Lloyd M., A case for business improvement districts in Scotland: Policy transfer in practice?, Plann. Pract. Res, 20, pp. 89-95, (2005); Blackwell M., A consideration of the UK Government’s proposals for business improvement districts in England. Issues and uncertainties, Prop. Manag, 23, pp. 194-203, (2005); Peel D., Lloyd G., Re-generating learning in the public realm: Evidence-based policy making and business improvement districts in the UK, Public Policy Adm, 23, pp. 189-205, (2008); Cook I., Private sector involvement in urban governance: The case of Business Improvement Districts and Town Centre Management partnerships in England, Geoforum, 40, pp. 930-940, (2009); Berg J., Private policing in South Africa: The Cape Town city improvement district—Pluralisation in practice, Soc. Trans, 35, pp. 224-250, (2004); Miraftab F., Governing post apartheid spatiality: Implementing city improvement districts in Cape Town, Antipode, 35, pp. 224-250, (2007); Hoyt L., Do Business Improvement District Organizations Make a Difference?: Crime In and Around Commercial Areas in Philadelphia, J. Plann. Educ. Res, 25, pp. 185-199, (2005); Hoyt L., Collecting private funds for safer public spaces: An empirical examination of the business improvement district concept, Environ. Plann. B, 31, pp. 367-380, (2004); Vindevogel F., Private security and urban crime mitigation: A bid for BIDs, Crim. Justice, 4, pp. 233-255, (2005); Caruso G., Weber R., Getting the max for the tax: An examination of BID performance measures, Int. J. Public Adm, 29, pp. 187-219, (2006); Brooks L., Volunteering to be taxed: Business improvement districts and the extra-governmental provision of public safety, J. Public Econ, 92, pp. 388-406, (2008); Morcol G., Zimmermann U., Community improvement districts in Metropolitan Atlanta, Int. J. Public Adm, 29, pp. 77-105, (2006); Meek J.W., Hubler P., Business improvement districts in Southern California: Implications for local governance, Int. J. Public Adm, 29, pp. 31-52, (2006); Morcol G., Patrick P.A., Business improvement districts in Pennsylvania: Implications for democratic metropolitan governance, Int. J. Public Adm, 29, pp. 137-171, (2006); Wolf J.F., Urban governance and business improvement districts: The Washington, DC BIDs, Int. J. Public Adm, pp. 53-75, (2006); Morcol G., Zimmermann U., Metropolitan governance and business improvement districts, Int. J. Public Adm, 29, pp. 5-29, (2006); Benit-Gbaffou C., Didier S., Peyroux E., Circulation of Security Models in Southern African Cities: Between Neoliberal Encroachment and Local Power Dynamics, Int. J. Urban Reg. Res, 36, pp. 877-889, (2012); Didier S., Peyroux E., Morange M., The spreading of the City Improvement District Model in Johannesburg and Cape Town: Urban regeneration and the neoliberal Agenda in South Africa, Int. J. Urban Reg. Res, 36, pp. 915-935, (2012); Peyroux E., Legitimating Business Improvement Districts in Johannesburg: A discursive perspective on urban regeneration and policy transfer, Eur. Urban Reg. Stud, 19, pp. 181-194, (2012); Didier S., Peyroux E., Morange M., The Adaptative Nature of Neoliberalism at the Local Scale: Fifteen Years of City Improvement Districts in Cape Town and Johannesburg, Antipode, 45, pp. 121-139, (2012); Michel B., When mobile policies drive against the wall. Limits of policy transfer using the example of Business Improvement Districts in Germany, Ber. Geogr. Landeskd, 87, pp. 87-102, (2013); Michel B., A global solution to local urban crises? Comparing discourses on business improvement districts in Cape Town and Hamburg, Urban Geogr, 34, pp. 1011-1030, (2013); Galcera I., Business improvement districts and urban sustainability. Regarding Catalan regulation on the urban Economic Activity Promotion Areas, Rev. Catalana Dret Ambient, 11, pp. 1-44, (2020); Kronkvist K., Ivert A.-K., A winning BID? The effects of a BID-inspired property owner collaboration on neighbourhood crime rates in Malmö, Sweden, Crime Prev. Community Saf, 2, pp. 134-152, (2020); Ward K., “Creating a Personality for Downtown”: Business Improvement Districts in Milwaukee, Urban Geogr, 28, pp. 781-808, (2007); Hoyt L., Planning through compulsory commercial clubs: Business improvement districts, Econ. Aff, 25, pp. 24-27, (2005); Berg J., Shearing C., New authorities: Relating state and non-state security auspices in South African improvement districts, Policing and the Politics of Order-Making, pp. 91-107, (2015); Brooks L., Unveiling Hidden Districts: Assessing the Adoption Patterns of Business Improvement Districts in California, Natl. Tax J, 1, pp. 5-24, (2007); Brooks L., Does spatial variation in heterogeneity matter? Assessing the adoption patterns of Business Improvement Districts, Int. J. Public Adm, 6, pp. 1219-1234, (2006); Cook I., Policing, partnerships, and profits: The operations of business improvement districts and town center management schemes in England, Urban Geogr, 31, pp. 453-478, (2010); Lee W., The Formation of Business Improvement Districts in Low-Income Immigrant Neighborhoods of Los Angeles, Urban Aff. Rev, 52, pp. 944-972, (2016); Lee W., Struggles to form business improvement districts (BIDs) in Los Angeles, Urban Stud, 53, pp. 3423-3438, (2016); Lee W., Downtown management and homelessness: The versatile roles of business improvement districts, J. Place Manag. Dev, 11, pp. 411-427, (2018); Lee W., Ferguson K.M., The role of local businesses in addressing multidimensional needs of homeless populations, J. Hum. Behav. Soc. Environ, 29, pp. 389-402, (2019); McCann E., Ward K., Relationality/territoriality: Toward a conceptualization of cities in the world, Geoforum, 41, pp. 175-184, (2010); McCann E., Ward K., A multi-disciplinary approach to policy transfer research: Geographies, assemblages, mobilities and mutations, Policy Stud. J, 34, pp. 2-18, (2013); Cook I., Ward K., Conferences, informational infrastructures and mobile policies: The process of getting Sweden ‘BID ready’, Eur. Urban Reg. Stud, 19, pp. 137-152, (2012); MacLeod G., Urban Politics Reconsidered: Growth Machine to Post-democratic City?, Urban Stud, 48, pp. 2629-2660, (2011); Hackworth J., Rekers J., Ethnic Packaging and Gentrification: The Case of Four Neighborhoods in Toronto, Urban Aff. Rev, 41, pp. 211-236, (2005); Cook P.J., MacDonald J., Public Safety Through Private Action: An Economic Assessment of BIDs, Econ. J, 121, pp. 445-462, (2011); Tait M., Jensen O.B., Travelling Ideas, Power and Place: The Cases of Urban Villages and Business Improvement Districts, Int. Plan Stud, 12, pp. 107-128, (2007); Mitchell J., Business Improvement Districts and the Management of Innovation, Am. Rev. Public Adm, 31, pp. 201-217, (2001); Gross J.S., Business Improvement Districts in New York City’s Low-Income and High-Income Neighborhoods, Econ. Dev. Q, 19, pp. 174-189, (2005); Hochleutner B.R., BIDs fare well the democratic accountability of business improvement districts, N. Y. Univ. Law Rev, 78, pp. 374-404, (2003); Morcol G., Vasavada T., Kim S., Business Improvement Districts in Urban Governance: A Longitudinal Case Study, Adm. Soc, 46, pp. 796-824, (2013); Morcol G., Karagoz T., Accountability of Business Improvement District in Urban Governance Networks: An Investigation of State Enabling Laws, Urban Aff. Rev, 56, pp. 888-918, (2018); Peel D., Lloyd G., Lord A., Business Improvement Districts and the Discourse of Contractualism, Eur. Plan. Stud, 17, pp. 401-422, (2009); Hogg S., Medway D., Warnaby G., Business improvement districts: An opportunity for SME retailing, Int. J. Retail. Distrib. Manag, 31, pp. 466-469, (2003); Hogg S., Medway D., Warnaby G., Performance Measurement in UK Town Centre Management Schemes and US Business Improvement Districts: Comparisons and UK Implications, Environ. Plan. A, 39, pp. 1513-1528, (2007); Stokes R.J., Business Improvement Districts and Inner City Revitalization: The Case Of Philadelphia’s Frankford Special Services District, Int. J. Public Adm, 29, pp. 173-186, (2006); Symes M., Steel M., Lessons from America: The role of business improvement districts as an agent of urban regeneration, Town Plan Rev, 74, pp. 301-313, (2003); Steel M., Symes M., The privatisation of public space? The American experience of business improvement districts and their relationship to lo-cal governance, Local Gov. Stud, 31, pp. 321-334, (2005); MacDonald J., Golinelli D., Stokes R.J., Bluthenthal R., The effect of business improvement districts on the incidence of violent crimes, Inj. Prev, 16, pp. 327-332, (2010); MacDonald J., Stokes R.J., Grunwald B., Bluthenthal R., The Privatization of Public Safety in Urban Neighborhoods: Do Business Improvement Districts Reduce Violent Crime Among Adolescents?, Law Soc. Rev, 47, pp. 621-652, (2013); Putz R., Stein C., Michel B., Glasze G., Business Improvement Districts in Germany-contextualization of a “mobile policy”, Geographische Zeitschrift, 101, pp. 82-100, (2014); Stein C., Michel B., Glasze G., Putz R., Learning from failed policy mobilities: Contradictions, resistances and unintended outcomes in the transfer of “Business Improvement Districts” to Germany, Eur. Urban Reg. Stud, 24, pp. 35-49, (2017)","D.G. Silva; Centre for Geographical Studies, Institute of Geography and Spatial Planning, University of Lisbon, Lisbon, 1600-276, Portugal; email: diogosilva4@campus.ul.pt","","MDPI","","","","","","20793197","","","","English","Computation","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85124902855" -"Yao X.; Xu Z.; Zizka M.","Yao, Xuan (57219672669); Xu, Zeshui (55502698400); Zizka, Miroslav (15057362200)","57219672669; 55502698400; 15057362200","TWENTY-FIVE YEARS OF “E&M ECONOMICS AND MANAGEMENT”: A BIBLIOMETRIC ANALYSIS","2023","E a M: Ekonomie a Management","26","1","","4","24","20","1","10.15240/TUL/001/2023-1-001","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85153592854&doi=10.15240%2fTUL%2f001%2f2023-1-001&partnerID=40&md5=16808f53bba5f39434e62d110c977203","Southeast University, School of Economics and Management, China; Sichuan University, Business School, China; Technical University of Liberec, Faculty of Economics, Czech Republic","Yao X., Southeast University, School of Economics and Management, China; Xu Z., Southeast University, School of Economics and Management, China, Sichuan University, Business School, China; Zizka M., Technical University of Liberec, Faculty of Economics, Czech Republic","E&M Economics and Management (E&M), originally founded in 1998, is dedicated to promoting advancements in the fields of Economics and Management based on theoretical and empirical analyses. Motivated by its 25th anniversary in 2023, this paper utilizes bibliometrics to make a comprehensive analysis of publications of the E&M that are included in Social Sciences Edition of the Web of Science (WoS). First, we make a performance analysis of the related publications to present the development and distribution of the E&M publications between January 2008 and April 2022 from the aspects of publication and citation structure. Second, a visual analysis of the literature called science-mapping analysis is implemented to display the structural and dynamic organization of knowledge of the E&M publications with the help of bibliometric tools VOSviewer and Bibliometrix. Finally, the paper discusses the evolution of E&M and some of the limitations and prospects to help editors and researchers understand how E&M has evolved over time and where it can be improved. This paper also provides a model of future effective analytical methods for assessing the data from a particular journal. According to the findings, researchers throughout the world publish in this journal on a regular basis. E&M is growing significantly during twenty-five years, and is becoming one of the influential journals in the fields of Economics and Management. © 2023, Technical University of Liberec. All rights reserved.","Bibliometric analysis; Bibliometrix.; E&M; Evolution; Science mapping","","","","","","","","Abhishek, Srivastava M., Mapping the influence of influencer marketing: A bibliometric analysis, Marketing Intelligence & Planning, 39, 7, pp. 979-1003, (2021); Belas J., Demjan V., Habanik J., Hudakova M., Sipko J., The business environment of small and medium-sized enterprises in selected regions of the Czech Republic and Slovakia, E&M Economics and Management, 18, 1, pp. 95-110, (2015); Broadus R., Toward a definition of bibliometrics, Scientometrics, 12, 5–6, pp. 373-379, (1987); Dabija D.-C., Bejan B. A. M., Tipi N., Generation X versus millennials communication behaviour on social media when purchasing food versus tourist services, E&M Economics and Management, 21, 1, pp. 191-205, (2018); Merigo J. M., Cobo M. J., Laengle S., Rivas D., Herrera-Viedma E., Twenty years of Soft Computing: A bibliometric overview, Soft Computing, 23, 5, pp. 1477-1497, (2019); Merigo J. M., Pedrycz W., Weber R., de la Sotta C., Fifty years of Information Sciences: A bibliometric overview, Information Sciences, 432, pp. 245-268, (2018); Pritchard A., Statistical bibliography or bibliometrics, Journal of Documentation, 25, 4, (1969); Qin Y., Xu Z. S., Wang X. X., Skare M., Green energy adoption and its determinants: A bibliometric analysis, Renewable and Sustainable Energy Reviews, 153, (2022); Soltes V., Gavurova B., The functionality comparison of the health care systems by the analytical hierarchy process method, E&M Economics and Management, 17, 3, pp. 100-117, (2014); Szabo Z. K., Soltes M., Herman E., Innovative capacity & performance of transition economies: Comparative study at the level of enterprises, E&M Economics and Management, 16, 1, pp. 52-68, (2013); Tang M., Liao H., Yepes V., Laurinavicius A., Tupenaite L., Quantifying and mapping the evolution of a leader journal in the field of civil engineering, Journal of Civil Engineering and Management, 27, 2, pp. 100-116, (2021); van Eck N. J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Wang X. X., Chang Y., Xu Z. S., Wang Z., Kadirkamanathan V., 50 years of International Journal of Systems Science: A review of the past and trends for the future, International Journal of Systems Science, 52, 8, pp. 1515-1538, (2021); Wang X. X., Xu Z. S., Ge Z. J., Zavadskas E. K., Skackauskas P., An overview of a leader journal in the field of transport: A bibliometric analysis of “Computer-Aided Civil and Infrastructure Engineering” from 2000 to 2019, Transport, 35, 6, pp. 557-575, (2020); Xiao Z. W., Qin Y., Xu Z. S., Antucheviciene J., Zavadskas E. K., The journal Buildings: A bibliometric analysis (2011–2021), Buildings, 12, 1, (2022); Yu D. J., Xu Z. S., Pedrycz W., Wang W., Information Sciences 1968–2016: A retrospective analysis with text mining and bibliometric, Information Sciences, 418, pp. 619-634, (2017); Yu D. J., Xu Z. S., Saparauskas J., The evolution of “Technological and Economic Development of Economy”: A bibliometric analysis, Technological and Economic Development of Economy, 25, 3, pp. 369-385, (2019); Zheng Y. H., Xu Z. S., Skare M., Porada-Rochon M., A comprehensive bibliometric analysis of the energy poverty literature: From 1942 to 2020, Acta Montanistica Slovaca, 26, 3, pp. 512-533, (2021); Zizka M., Ten years of existence of the E+M Economics and Management journal, E&M Economics and Management, 11, 3, pp. 6-22, (2008)","Z. Xu; Sichuan University, Business School, China; email: xuzeshui@263.net","","Technical University of Liberec","","","","","","12123609","","","","English","E M Ekon. Manage.","Editorial","Final","All Open Access; Bronze Open Access; Green Open Access","Scopus","2-s2.0-85153592854" -"Alzard M.H.; El-Hassan H.; El-Maaddawy T.; Hassan A.A.; Alsalami M.; Abdulrahman F.","Alzard, Mohammed H. (57193922107); El-Hassan, Hilal (55779200500); El-Maaddawy, Tamer (14029790000); Hassan, Ashraf Aly (57213162034); Alsalami, Marwa (57437552000); Abdulrahman, Fatma (57909841200)","57193922107; 55779200500; 14029790000; 57213162034; 57437552000; 57909841200","Self-Healing Concrete: A Bibliometric Analysis","2022","World Congress on Civil, Structural, and Environmental Engineering","","","ICSECT 143","","","","1","10.11159/icsect22.143","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85139024005&doi=10.11159%2ficsect22.143&partnerID=40&md5=cdfb73cc6034e494807971a26504a446","United Arab Emirates University, Al Ain, United Arab Emirates; Ministry of Energy and Infrastructure, Abu Dhabi, United Arab Emirates","Alzard M.H., United Arab Emirates University, Al Ain, United Arab Emirates; El-Hassan H., United Arab Emirates University, Al Ain, United Arab Emirates; El-Maaddawy T., United Arab Emirates University, Al Ain, United Arab Emirates; Hassan A.A., United Arab Emirates University, Al Ain, United Arab Emirates; Alsalami M., Ministry of Energy and Infrastructure, Abu Dhabi, United Arab Emirates; Abdulrahman F., Ministry of Energy and Infrastructure, Abu Dhabi, United Arab Emirates","– Research on self-healing concrete has thrived in recent years. This study aims to map the evolution of self-healing concrete among the different research constituents, reveal the trends, and identify the key contributors, research themes, and critical publication outlets and topics in the field. Bibliometrix R software package was utilized to conduct a bibliometric analysis on a total of 1,402 publications written by 2,880 authors and published between 1974 to 2021. These publications were retrieved from the Scopus database. Performance analysis revealed that 86% of the publications were journal articles and papers published in conference proceedings. Citations and keywords analysis showed that review articles were the most cited papers, and research on utilizing bacteria in self-healing concrete was the most trending topic. High collaboration rates among top-cited and most productive countries, authors, and universities were reported using science mapping. The findings of this study highlight the need for future work focused on real-life applications, optimization of self-healing mechanisms, rheological properties, and microstructure characteristics of self-healing concrete. © 2022, Avestia Publishing. All rights reserved.","Bibliometric analysis; Bibliometrix; Performance analysis; Science mapping; Self-healing concrete","","","","","","Ministry of Energy and Infrastructure, (21R084); United Arab Emirates University, UAEU, (12N044); United Arab Emirates University, UAEU","The authors gratefully acknowledge the financial support of UAE University under grant number 12N044 and the Ministry of Energy and Infrastructure in UAE under grant number 21R084.","Zhang W., Zheng Q., Ashour A., Han B., Self-healing cement concrete composites for resilient infrastructures: A review, Composites Part B: Engineering, 189, (2020); Sidiq A., Gravina R., Giustozzi F., Is concrete healing really efficient? A review, Construction and Building Materials, 205, pp. 257-273, (2019); Kachouh N., El-Maaddawy T., El-Hassan H., El-Ariss B., Shear Behavior of Steel-Fiber-Reinforced Recycled Aggregate Concrete Deep Beams, Buildings, 11, 9, (2021); El-Hassan H., Medljy J., El-Maaddawy T., Properties of Steel Fiber-Reinforced Alkali-Activated Slag Concrete Made with Recycled Concrete Aggregates and Dune Sand, Sustainability, 13, 14, (2021); El-Hassan H., Elkholy S., Enhancing the performance of Alkali-Activated Slag-Fly ash blended concrete through hybrid steel fiber reinforcement, Construction and Building Materials, 311, (2021); El-Hassan H., Hussein A., Medljy J., El-Maaddawy T., Performance of Steel Fiber-Reinforced Alkali-Activated Slag-Fly Ash Blended Concrete Incorporating Recycled Concrete Aggregates and Dune Sand, Buildings, 11, 8, (2021); Wang X. F., Yang Z. H., Fang C., Han N. X., Zhu G. M., Tang J. N., Xing F., Evaluation of the mechanical performance recovery of self-healing cementitious materials – its methods and future development: A review, Construction and Building Materials, 212, pp. 400-421, (2019); Vijay K., Murmu M., Deo S. V., Bacteria based self-healing concrete – A review, Construction and Building Materials, 152, pp. 1008-1014, (2017); Xu J., Yao W., Multiscale mechanical quantification of self-healing concrete incorporating non-ureolytic bacteriabased healing agent, Cement and Concrete Research, 64, pp. 1-10, (2014); Mahmoodi S., Sadeghian P., Self-Healing Concrete: A Review of Recent Research Developments and Existing Research Gaps, (2019); Sh A. Z., Self-healing concrete: definition, mechanism and application in different types of structures, Международный научно-исследовательский журнал, 59, (2017); Sonali Sri Durga C., Ruben N., Sri Rama Chand M., Venkatesh C., Performance studies on rate of self healing in bio concrete, Materials Today: Proceedings, 27, pp. 158-162, (2020); Nasim M., Dewangan U. K., Deo S. V., Autonomous healing in concrete by crystalline admixture: A review, Materials Today: Proceedings, 32, pp. 638-644, (2020); Yang Q., Jinbang W., Lianwang Y., Zonghui Z., Effect of graphene and carbon fiber on repairing crack of concrete by electrodeposition, Ceramics-Silikaty, 63, 4, pp. 403-412, (2019); Wang J. Y., Soens H., Verstraete W., De Belie N., Self-healing concrete by use of microencapsulated bacterial spores, Cement and Concrete Research, 56, pp. 139-152, (2014); Feng J., Dong H., Wang R., Su Y., A novel capsule by poly (ethylene glycol) granulation for self-healing concrete, Cement and Concrete Research, 133, (2020); da Silva F. B., De Belie N., Boon N., Verstraete W., Production of non-axenic ureolytic spores for self-healing concrete applications, Construction and Building Materials, 93, pp. 1034-1041, (2015); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Song T., Jiang B., Li Y., Ji Z., Zhou H., Jiang D., Seok I., Murugadoss V., Wen N., Colorado H., Self-healing Materials: A Review of Recent Developments, ES Materials & Manufacturing, 14, pp. 1-19, (2021); Linnenluecke M. K., Marrone M., Singh A. K., Conducting systematic literature reviews and bibliometric analyses, Australian Journal of Management, 45, 2, pp. 175-194, (2020); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W. M., How to conduct a bibliometric analysis: An overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Aria M., Cuccurullo C., Biblioshiny-The shiny interface for bibliometrix, Biblioshiny-The shiny interface for bibliometrix, (2016); About Scopus-Abstract and citation database | Elsevier; De Muynck W., De Belie N., Verstraete W., Microbial carbonate precipitation in construction materials: A review, Ecological Engineering, 36, 2, (2010); Hager M. D., Greil P., Leyens C., van der Zwaag S., Schubert U. S., Self-Healing Materials, Advanced Materials, 22, 47, pp. 5424-5430, (2010); Edvardsen C., Water Permeability and Autogenous Healing of Cracks in Concrete, MJ, 96, 4, pp. 448-454, (1999); Jonkers H. M., Thijssen A., Muyzer G., Copuroglu O., Schlangen E., Application of bacteria as self-healing agent for the development of sustainable concrete, Ecological Engineering, 36, 2, pp. 230-235, (2010); Wiktor V., Jonkers H. M., Quantification of crack-healing in novel bacteria-based self-healing concrete, Cement and Concrete Composites, 33, 7, pp. 763-770, (2011); Van Tittelboom K., De Belie N., Self-Healing in Cementitious Materials—A Review, Materials, 6, 6, (2013); Reinhardt H.-W., Jooss M., Permeability and self-healing of cracked concrete as a function of temperature and crack width, Cement and Concrete Research, 33, 7, pp. 981-985, (2003); Wang J., Van Tittelboom K., De Belie N., Verstraete W., Use of silica gel or polyurethane immobilized bacteria for self-healing concrete, Construction and Building Materials, 26, 1, pp. 532-540, (2012); Van Tittelboom K., De Belie N., Van Loo D., Jacobs P., Self-healing efficiency of cementitious materials containing tubular capsules filled with healing agent, Cement and Concrete Composites, 33, 4, pp. 497-505, (2011)","","El Naggar H.; Barros J.; Cachim P.","Avestia Publishing","","7th World Congress on Civil, Structural, and Environmental Engineering, CSEE 2022","10 April 2022 through 12 April 2022","Virtual, Online","283179","23715294","978-192787799-9","","","English","World Cong. Civ., Struct., Environ. Eng.","Conference paper","Final","All Open Access; Bronze Open Access","Scopus","2-s2.0-85139024005" -"Moresi E.A.D.; Pinho I.; Costa A.P.","Moresi, Eduardo Amadeu Dutra (35088456900); Pinho, Isabel (6507175276); Costa, António Pedro (55437584900)","35088456900; 6507175276; 55437584900","How to Operate Literature Review Through Qualitative and Quantitative Analysis Integration?","2022","Lecture Notes in Networks and Systems","466 LNNS","","","194","210","16","9","10.1007/978-3-031-04680-3_13","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85130369828&doi=10.1007%2f978-3-031-04680-3_13&partnerID=40&md5=8a20079275b9108e4e679347a0853a90","Catholic University of Brasília, DF, Brasília, 71966-700, Brazil; University of Aveiro, Aveiro, 3810-193, Portugal","Moresi E.A.D., Catholic University of Brasília, DF, Brasília, 71966-700, Brazil; Pinho I., University of Aveiro, Aveiro, 3810-193, Portugal; Costa A.P., University of Aveiro, Aveiro, 3810-193, Portugal","Usually, a literature review takes time and becomes a demanding step in any research project. The proposal presented in this article intends to structure this work in an organised and transparent way for all project participants and the structured elaboration of its report. Integrating qualitative and quantitative analysis provides opportunities to carry out a solid, practical, and in-depth literature review. The purpose of this article is to present a guide that explores the potentials of qualitative and quantitative analysis integration to develop a solid and replicable literature review. The paper proposes an integrative approach comprising six steps: 1) research design; 2) Data Collection for bibliometric analysis; 3) Search string refinement; 4) Bibliometric analysis; 5) qualitative analysis; and 6) report and dissemination of research results. These guidelines can facilitate the bibliographic analysis process and relevant article sample selection. Once the sample of publications is defined, it is possible to conduct a deep analysis through Content Analysis. Software tools, such as R Bibliometrix, VOSviewer, Gephi, yEd and webQDA, can be used for practical work during all collection, analysis, and reporting processes. From a large amount of data, selecting a sample of relevant literature is facilitated by interpreting bibliometric results. The specification of the methodology allows the replication and updating of the literature review in an interactive, systematic, and collaborative way giving a more transparent and organised approach to improving the literature review. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.","Bibliometric analysis; CAQDAS; Qualitative analysis; Quantitative analysis; Science mapping","","","","","","","","Pritchard A., Statistical bibliography or bibliometrics?, J. Doc., 25, 4, pp. 348-349, (1969); Nalimov V., Mulcjenko B., Measurement of Science: Study of the Development of Science as an Information Process. Foreign Technology Division, (1971); Hugar J.G., Bachlapur M.M., Gavisiddappa A., Research contribution of bibliometric studies as reflected in web of science from 2013 to 2017, Libr. Philos. Pract. (E-Journal, pp. 1-13, (2019); Verma M.K., Shukla R., Library herald-2008–2017: A bibliometric study. Libr. Philos, Pract. (E-Journal), pp. 2-12, (2018); Pandita R., Annals of library and information studies (ALIS) journal: A bibliometric study (2002–2012), DESIDOC J. Libr. Inf. Technol., 33, 6, pp. 493-497, (2013); Kannan P., Thanuskodi S., Bibliometric analysis of library philosophy and practice: a study based on scopus database, Libr. Philos. Pract. (E-Journal, pp. 1-13, (2019); Khalife M.A., Dunay A., Illes C.B., Bibliometric analysis of articles on project management research, Periodica Polytechnica Soc. Manag. Sci., 29, 1, pp. 70-83, (2021); Pech G., Delgado C., Screening the most highly cited papers in longitudinal bibliometric studies and systematic literature reviews of a research field or journal: Widespread used metrics vs a percentile citation-based approach, J. Informet., 15, 3, (2021); Das D., Journal of informetrics: A bibliometric study, Libr. Philos. Pract. (E-Journal, pp. 1-15, (2021); Schmidt F., Meta-analysis: A constantly evolving research integration tool, Organ. Res. Methods, 11, 1, pp. 96-113, (2008); Zupic I., Cater T., Bibliometric methods in management organisation, Organ. Res. Methods, 18, 3, pp. 429-472, (2014); Noyons E., Moed H., Luwel M., Combining mapping and citation analysis for evaluative bibliometric purposes: A bibliometric study, J. Am. Soc. Inf. Sci., 50, pp. 115-131, (1999); van Rann A., Measuring science. Capita selecta of current main issues, Handbook of Quantitative Science and Technology Research, pp. 19-50, (2004); Garfield E., Citation analysis as a tool in journal evaluation, Science, 178, pp. 417-479, (1972); Hirsch J., An index to quantify an individuals scientific research output, Proceedings of the National Academy of Sciences, Vol. 102, pp. 16569-21657, (2005); Cobo M., Lopez-Herrera A., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis and cooperative study among tools, J. Am. Soc. Inform. Sci. Technol., 62, pp. 1382-1402, (2011); Noyons E., Moed H., van Rann A., Integrating research perfomance analysis and science mapping, Scientometrics, 46, pp. 591-604, (1999); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: An overview and guidelines, J. Bus. Res., 133, pp. 285-296, (2021); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informet., 11, 4, pp. 959-975, (2017); Aria M., Cuccurullo C., Package ‘bibliometrix, (2020); Borner K., Chen C., Boyack K., Visualisingg knowledge domains, Ann. Rev. Inf. Sci. Technol., 37, pp. 179-255, (2003); Morris S., van der Veer Martens B., Mapping research specialities, Ann. Rev. Inf. Sci. Technol., 42, pp. 213-295, (2008); Zitt M., Ramanana-Rahary S., Bassecoulard E., Relativity of citation performance and excellence measures: From cross-field to cross-scale effects of field-normalisation, Scientometrics, 63, 2, pp. 373-401, (2005); Li L.L., Ding G., Feng N., Wang M.-H., Ho Y.-S., Global stem cell research trend: Bibliometric analysis as a tool for mapping trends from 1991 to 2006, Scientometrics, 80, 1, pp. 9-58, (2009); Ebrahim A.N., Salehi H., Embi M.A., Tanha F.H., Gholizadeh H., Motahar S.M., Visibility and citation impact, Int. Educ. Stud., 7, 4, pp. 120-125, (2014); Canas-Guerrero I., Mazarron F.R., Calleja-Perucho C., Pou-Merina A., Bibliometric analysis in the international context of the “construction & building technology” category from the web of science database, Constr. Build. Mater., 53, pp. 13-25, (2014); Gaviria-Marin M., Merigo J.M., Baier-Fuentes H., Knowledge management: A global examination based on bibliometric analysis, Technol. Forecast. Soc. Chang., 140, pp. 194-220, (2019); Heradio R., Perez-Morago H., Fernandez-Amoros D., Javier Cabrerizo F., Herrera-Viedma E., A bibliometric analysis of 20 years of research on software product lines, Inf. Softw. Technol., 72, pp. 1-15, (2016); Furstenau L.B., Et al., Link between sustainability and industry 4.0: Trends, challenges and new perspectives, IEEE Access, 8, pp. 140079-140096, (2020); van Eck N.J., Waltman L., Vosviewer Manual, (2021); Bastian M., Heymann S., Jacomy M., Gephi: An open source software for exploring and manipulating networks, Proceedings of the Third International ICWSM Conference, pp. 361-362, (2009); Chen C., How to Use Citespace, (2019); Moresi E.A.D., Pierozzi Junior I., Representação do conhecimento para ciência e tecnologia: Construindo uma sistematização metodológica, 16Th International Conference on Information Systems and Technology Management, (2019); Moresi E.A.D., Pinho I., Proposta de abordagem para refinamento de pesquisa bibliográfica, New Trends Qual. Res., 9, pp. 11-20, (2021); Moresi E.A.D., Pinho I., Como identificar os tópicos emergentes de um tema de investigação?, New Trends Qual. Res., 9, pp. 46-55, (2021); Chen Y.H., Chen C.Y., Lee S.C., Technology forecasting of new clean energy: The example of hydrogen energy and fuel cell, Afr. J. Bus. Manag., 4, 7, pp. 1372-1380, (2010); Ernst H., The use of patent data for technological forecasting: The diffusion of CNC-technology in the machine tool industry, Small Bus. Econ., 9, 4, pp. 361-381, (1997); Chen C., Science mapping: A systematic review of the literature, J. Data Inf. Sci., 2, 2, pp. 1-40, (2017); Prabhakaran T., Lathabai H.H., Changat M., Detection of paradigm shifts and emerging fields using scientific network: A case study of information technology for engineering, Technol. Forecast. Soc. Change, 91, pp. 124-145, (2015); Klavans R., Boyack K.W., Identifying a better measure of relatedness for mapping science, J. Am. Soc. Inf. Sci., 57, 2, pp. 251-263, (2006); Kauffman J., Kittas A., Bennett L., Tsoka S., DyCoNet: A Gephi plugin for community detection in dynamic complex networks, Plos ONE, 9, 7, (2014); Grant M.J., Booth A., A typology of reviews: An analysis of 14 review types and associated methodologies, Health Info. Libr. J., 26, 2, pp. 91-108, (2009); Costa A.P., Soares C.B., Fornari L., Pinho I., Revisão Da Literatura Com Apoio De Software-Contribuição Da Pesquisa Qualitativa. Ludomedia, (2019); Tranfield D., Denyer D., Smart P., Towards a methodology for developing evidence-informed management knowledge by means of systematic review, Br. J. Manag., 14, 3, pp. 207-222, (2003); Costa A.P., Amado J., Content Analysis Supported by Software, (2018); Pinho I., Leite D., Doing a literature review using content analysis-research networks review, Atas CIAIQ 2014-Investigação Qualitativa Em Ciências Sociais, 3, pp. 377-378, (2014); White M.D., Marsh E.E., Content analysis: A flexible methodology, Libr. Trends, 55, 1, pp. 22-45, (2006); Souza F.N., Neri D., Costa A.P., Asking questions in the qualitative research context, Qual. Rep., 21, 13, pp. 6-18, (2016); Pinho I., Pinho C., Rosa M.J., Research evaluation: Mapping the field structure, Avaliação: Revista Da Avaliação Da Educação Superior (Campinas), 25, pp. 546-574, (2020)","E.A.D. Moresi; Catholic University of Brasília, Brasília, DF, 71966-700, Brazil; email: moresi@p.ucb.br","Costa A.P.; Moreira A.; Sánchez‑Gómez M.C.; Wa-Mbaleka S.","Springer Science and Business Media Deutschland GmbH","","6th World Conference on Qualitative Research, WCQR 2022","26 January 2022 through 28 January 2022","Virtual, Online","277539","23673370","978-303104679-7","","","English","Lect. Notes Networks Syst.","Conference paper","Final","","Scopus","2-s2.0-85130369828" -"Filho L.B.S.; Coelho R.C.; Muniz E.C.; Barbosa H.D.S.","Filho, Luiz B.S. (57749497200); Coelho, Ronaldo C. (57208655061); Muniz, Edvani C. (7005651884); Barbosa, Herbert de S. (36514134200)","57749497200; 57208655061; 7005651884; 36514134200","Optimization of pectin extraction using response surface methodology: A bibliometric analysis","2022","Carbohydrate Polymer Technologies and Applications","4","","100229","","","","19","10.1016/j.carpta.2022.100229","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85132234993&doi=10.1016%2fj.carpta.2022.100229&partnerID=40&md5=c4c9595aea275b890dab82388d7b222b","Study Group in Bioanalytics – GEBIO, Chemistry Department, Federal University of Piauí, PI, Teresina, 64049-550, Brazil; Chemistry Department, Federal Institute of Piauí, PI, Teresina, 64053-390, Brazil; Chemistry Department, Federal University of Piauí, PI, Teresina, 64049-550, Brazil; Chemistry Department, State University of Maringá, PR, Maringá, 87020-900, Brazil","Filho L.B.S., Study Group in Bioanalytics – GEBIO, Chemistry Department, Federal University of Piauí, PI, Teresina, 64049-550, Brazil, Chemistry Department, Federal Institute of Piauí, PI, Teresina, 64053-390, Brazil; Coelho R.C., Study Group in Bioanalytics – GEBIO, Chemistry Department, Federal University of Piauí, PI, Teresina, 64049-550, Brazil, Chemistry Department, Federal Institute of Piauí, PI, Teresina, 64053-390, Brazil; Muniz E.C., Chemistry Department, Federal University of Piauí, PI, Teresina, 64049-550, Brazil, Chemistry Department, State University of Maringá, PR, Maringá, 87020-900, Brazil; Barbosa H.D.S., Study Group in Bioanalytics – GEBIO, Chemistry Department, Federal University of Piauí, PI, Teresina, 64049-550, Brazil","In this study, 209 articles have been surveyed on the “Pectin Extraction via Response Surface Methodology (RSM)” that have been collected from Web of Science© and Scopus©, and analyzed by using Bibliometrix, an RStudio package for science mapping analysis. Trends in the optimization and extraction methods of pectin via RSM have been pointed out, which may be useful for further research. Results shown that publications on “Pectin Extraction via RSM” have started for more than 20 years, with a growing trend, more than triplicating in the last 10 years. Based on such set of papers, China has been the most active country in local productions, whereas Iran, Brazil, India, and the United Kingdom have contributed with international-wide collaborative publications in optimization pectin extraction through RSM. Assisted extraction categories, physical and functional properties of pectin have taken on more relevance by 2012, especially with consolidation of microwave-assisted and ultrasound-assisted extraction techniques. © 2022","Bibliometric; Co-citation; Extraction; Optimization; Optimization of methods for pectin; Pectin","","","","","","Federal Institute of Piauí; IFPI; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES; Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq, (307429/2018–0, 408767/2021–9)","The authors are grateful to Coordenação de Aperfeiçoameneto de Pessoal de Nível Superior, CAPES, Brazil. ECM thanks to CNPq (Grant #307429/2018–0 and 408767/2021–9). LBSF would like to thank the Federal Institute of Piauí (IFPI) for the encouragement and support for his doctorate. Also, LBSF thanks to Dr. H.S. Barbosa and Prof. E.C. Muniz for their encouragement and guidance.","Adetunji L.R., Adekunle A., Orsat V., Raghavan V., Advances in the pectin production process using novel extraction techniques: A review, Food Hydrocolloids (Vol. 62, pp. 239-250, (2017); Al-Amoudi R.H., Taylan O., Kutlu G., Can A.M., Sagdic O., Dertli E., Et al., Characterization of chemical, molecular, thermal and rheological properties of medlar pectin extracted at optimum conditions as determined by Box-Behnken and ANFIS models, Food Chemistry, 271, pp. 650-662, (2019); Amaral S., da C., Roux D., Caton F., Rinaudo M., Barbieri S.F., Et al., Extraction, characterization and gelling ability of pectins from Araçá (Psidium cattleianum Sabine) fruits, Food Hydrocolloids, 121, (2021); Appio F.P., Cesaroni F., di Minin A., Visualizing the structure and bridges of the intellectual property management and strategy literature: a document co-citation analysis, Scientometrics, 101, 1, pp. 623-661, (2014); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Asgari K., Labbafi M., Khodaiyan F., Kazemi M., Hosseini S.S., High-methylated pectin from walnut processing wastes as a potential resource: Ultrasound assisted extraction and physicochemical, structural and functional analysis, International Journal of Biological Macromolecules, 152, pp. 1274-1282, (2020); Asgari K., Labbafi M., Khodaiyan F., Kazemi M., Hosseini S.S., Valorization of walnut processing waste as a novel resource: Production and characterization of pectin, Journal of Food Processing and Preservation, 12, (2020); Barrero-Fernandez A., Aguado R., Moral A., Brindley C., Ballesteros M., Applications of cellulose-based agents for flocculation processes: A bibliometric analysis, Cellulose, 28, 15, pp. 9857-9871, (2021); Barrios M., Borrego A., Vilagines A., Olle C., Somoza M., A bibliometric study of psychological research on tourism, Scientometrics, 77, 3, pp. 453-467, (2008); Begum R., Aziz M.G., Yusof Y.A., Saifullah M., Uddin M.B., Evaluation of gelation properties of jackfruit (Artocarpus heterophyllus) waste pectin, Carbohydrate Polymer Technologies and Applications, 2, (2021); Bu Y., Wang B., Huang W., bin, Che S., Huang Y., Using the appearance of citations in full text on author co-citation analysis, Scientometrics, 116, 1, pp. 275-289, (2018); Buchweitz M., Speth M., Kammerer D.R., Carle R., Impact of pectin type on the storage stability of black currant (Ribes nigrum L.) anthocyanins in pectic model solutions, Food Chemistry, 139, 1-4, pp. 1168-1178, (2013); Candioti L.V., de Zan M.M., Camara M.S., Goicoechea H.C., Experimental design and multiple response optimization. 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Muniz; Chemistry, Universidade Estadual de Maringa, Maringá, Av. Colombo 5790, 87020900, Brazil; email: munizec@ufpi.edu.br","","Elsevier Ltd","","","","","","26668939","","","","English","Carbohydr. Polym. Technol. Appl.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85132234993" -"Monteagudo-Fernández J.; Gómez-Carrasco C.J.; Chaparro-Sainz Á.","Monteagudo-Fernández, José (57218175076); Gómez-Carrasco, Cosme J. (55576704700); Chaparro-Sainz, Álvaro (57196122640)","57218175076; 55576704700; 57196122640","Heritage education and research in museums. Conceptual, intellectual and social structure within a knowledge domain (2000–2019)","2021","Sustainability (Switzerland)","13","12","6667","","","","21","10.3390/su13126667","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108435268&doi=10.3390%2fsu13126667&partnerID=40&md5=7f9c4871757cfc8c104e84900b940507","Department of Mathematics and Social Sciences Education, University of Murcia, Murcia, 30100, Spain; Department of Education, University of Almeria, Almería, 04120, Spain","Monteagudo-Fernández J., Department of Mathematics and Social Sciences Education, University of Murcia, Murcia, 30100, Spain; Gómez-Carrasco C.J., Department of Mathematics and Social Sciences Education, University of Murcia, Murcia, 30100, Spain; Chaparro-Sainz Á., Department of Education, University of Almeria, Almería, 04120, Spain","Heritage and museums have constituted two fundamental axes of heritage education research in recent decades. This can be defined as the pedagogical process in which people can learn about heritage assets in formal or informal learning contexts. Museums, as centres of reference in informal education, are in constant and fluid contact with schools and produce different and varied didactic materials related to heritage. This paper provides results concerning the development and shaping of the knowledge domain known as heritage education between 2000 and 2019 on the Web of Science (WoS). To this end, different techniques and tools have been used: R-package Bibliometrix and VOSviewer. This analysis has identified five clusters with the topics underpinning heritage education as a specific field of knowledge. Our inquiry has highlighted the fact that there has been an increase in production regarding research topics associated with heritage education and museums in this period, particularly between 2015 and 2019. The inclusion of ESCI journals has led to a greater visibility of WoS-indexed academic production in some countries. Finally, the concepts “heritage”, “museum” and “education” are the axes around which the research paradigms related to heritage education research seem to have been developed. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.","Bibliometric analysis; Heritage education; Museum research; Research review; Science mapping","academic research; education; museum; social structure; underpinning","","","","","Fundación Séneca, (20638/JLI/18); Ministerio de Ciencia, Innovación y Universidades, MCIU, (PGC2018-094491-B-C33)","Funding: This work was supported by the Spanish Ministry of Science, Innovation and Universities under Grant number PGC2018-094491-B-C33 and the Fundación Séneca under Grant number 20638/JLI/18.","Cuenca-Lopez J.M., Martin-Caceres M.J., Estepa-Gimenez J., Teacher training in heritage education: Good practices for citizenship education, Humanit. Soc. 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Monteagudo-Fernández; Department of Mathematics and Social Sciences Education, University of Murcia, Murcia, 30100, Spain; email: jose.monteagudo@um.es","","MDPI AG","","","","","","20711050","","","","English","Sustainability","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85108435268" -"Kesavan V.; Srinivasan K.S.","Kesavan, Varun (57704438300); Srinivasan, Kandaswamy Sakthi (58565008300)","57704438300; 58565008300","Present state and future directions of mobile payments system: a historical and bibliographic examination","2024","International Journal of Process Management and Benchmarking","18","3","","329","351","22","0","10.1504/IJPMB.2024.142145","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207239826&doi=10.1504%2fIJPMB.2024.142145&partnerID=40&md5=ff3d1d43d41547bdeaa533462cacca50","VIT Business School, Vellore Institute of Technology, VIT University, Vellore, India","Kesavan V., VIT Business School, Vellore Institute of Technology, VIT University, Vellore, India; Srinivasan K.S., VIT Business School, Vellore Institute of Technology, VIT University, Vellore, India","M-payments or mobile payments are fast becoming the norm since they minimise the need for traditional currency in a variety of everyday situations. Seldom have bibliometric studies been conducted in mobile payments research. The aim of this research is to examine the current level of research on M-payment systems. This research targets to provide a comprehensive review of the research on smartphone payments. This study investigates both scholarly articles and open-access studies. The articles published between 2010 and 2022 were selected using the Scopus database. During the first search, 2,400 papers were located, however only 662 were included in the research. The bibliometric analysis is conducted using the Biblioshiny R-studio. Throughout history, there has been a rising tendency in the rate of publishing. India, USA, and China are three major benefactors. Extensive study on mobile payments, mobile payments, financial inclusion, FinTech, and mobile money has been conducted. This examination of mobile payments, mobile payment, FinTech, mobile money, and mobile banking address knowledge gaps, organises essential themes, adds to the current literature, and sets the way for future scholars. Copyright © 2024 Inderscience Enterprises Ltd.","bibliometric analysis; Bibliometrix; mobile payments system; payment systems; Science mapping; Scopus database; technological change","","","","","","","","Abdullah and Naved Khan M., Determining mobile payment adoption: a systematic literature search and bibliometric analysis, Cogent Business & Management, 8, 1, (2021); Aker J.C., Dial ‘A’ for agriculture: a review of information and communication technologies for agricultural extension in developing countries, Agricultural Economics, 42, 6, pp. 631-647, (2011); Alalwan A.A., Dwivedi Y.K., Rana N.P., Factors influencing adoption of mobile banking by Jordanian bank customers: Extending UTAUT2 with trust, International Journal of Information Management, 37, 3, pp. 99-110, (2017); Aydin G., Burnaz S., Adoption of mobile payment systems: a study on mobile wallets, Journal of Business, Economics and Finance, 5, 1, (2016); Bezhovski Z., The Future of the mobile payment as electronic payment system, European Journal of Business and Management, 8, 8, pp. 127-132, (2016); 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Ozili P.K., Impact of digital finance on financial inclusion and stability, Borsa Istanbul Review, 18, 4, pp. 329-340, (2018); Schierz P.G., Schilke O., Wirtz B.W., Understanding consumer acceptance of mobile payment services: an empirical analysis, Electronic Commerce Research and Applications, 9, 3, pp. 209-216, (2010); Singh S., Dhir S., Structured review using TCCM and bibliometric analysis of international cause-related marketing, social marketing, and innovation of the firm, International Review on Public and Nonprofit Marketing, 16, 2–4, pp. 335-347, (2019); Slade E.L., Dwivedi Y.K., Piercy N.C., Williams M.D., Modeling consumers’ adoption intentions of remote mobile payments in the United Kingdom: extending UTAUT with innovativeness, risk, and trust, Psychology & Marketing, 32, 8, pp. 860-873, (2015); Suri T., Jack W., The long-run poverty and gender impacts of mobile money, Science, 354, 6317, pp. 1288-1292, (2016); Thakur R., Srivastava M., Adoption readiness, personal innovativeness, perceived risk, and usage intention across customer groups for mobile payment services in India, Internet Research, 24, 3, pp. 369-392, (2014); Zhou T., An empirical examination of continuance intention of mobile payment services, Decision Support Systems, 54, 2, pp. 1085-1091, (2013); Zhou T., Lu Y., Wang B., Integrating TTF and UTAUT to explain mobile banking user adoption, Computers in Human Behavior, 26, 4, pp. 760-767, (2010)","K.S. Srinivasan; VIT Business School, Vellore Institute of Technology, VIT University, Vellore, India; email: ksakthisrinivasan@vit.ac.in","","Inderscience Publishers","","","","","","14606739","","","","English","Int. J. Process Manage. Benchmarking","Article","Final","","Scopus","2-s2.0-85207239826" -"Di Cosmo A.; Pinelli C.; Scandurra A.; Aria M.; D’aniello B.","Di Cosmo, Anna (6701576625); Pinelli, Claudia (7003748076); Scandurra, Anna (56090826300); Aria, Massimo (23388148900); D’aniello, Biagio (57203148440)","6701576625; 7003748076; 56090826300; 23388148900; 57203148440","Research trends in octopus biological studies","2021","Animals","11","6","1808","","","","36","10.3390/ani11061808","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107975560&doi=10.3390%2fani11061808&partnerID=40&md5=9c364d5e49adc0d1b5ab863dc9eae14e","Department of Biology, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; Department of Environmental, Biological and Pharmaceutical Sciences & Technologies, University of Campania “Luigi Vanvitelli”, Caserta, 81100, Italy; Department of Economics and Statistics, University of Naples Federico II, via Cinthia, Naples, 80126, Italy","Di Cosmo A., Department of Biology, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; Pinelli C., Department of Environmental, Biological and Pharmaceutical Sciences & Technologies, University of Campania “Luigi Vanvitelli”, Caserta, 81100, Italy; Scandurra A., Department of Biology, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; Aria M., Department of Economics and Statistics, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; D’aniello B., Department of Biology, University of Naples Federico II, via Cinthia, Naples, 80126, Italy","Octopuses represent interesting model studies for different fields of scientific inquiry. The present study provides a bibliometric analysis on research trends in octopuses biological studies. The analysis was executed from January 1985 to December 2020 including scientific products reported in the Web of Science database. The period of study was split into two blocks (“earlier period” (EP): 1985−2010; “recent period” (RP): 2011−2020) to analyze the evolution of the research topics over time. All publications of interest were identified by using the following query: ((AK = octopus) OR (AB = octopus) OR (TI = octopus)). Data information was converted into an R-data frame using bibliometrix. Octopuses studies appeared in 360 different sources in EP, while they increased to 408 in RP. Sixty countries contributed to the octopuses studies in the EP, while they were 78 in the RP. The number of affiliations also increased between EP and RP, with 835 research centers involved in the EP and 1399 in the RP. In the EP 5 clusters (i.e., “growth and nutrition”, “pollution impact”, “morphology”, “neurobiology”, “biochemistry”) were represented in a thematic map, according to their centrality and density ranking. In the RP the analysis identified 4 clusters (i.e., “growth and nutrition”, “ecology”, “pollution impact”, “genes, behavior, and brain evolution”). The UK with Ireland, and the USA with Canada shared the highest number of publications in the EP, while in the RP, Spain and Portugal were the leading countries. The current data provide significant insight into the evolving trends in octopuses studies. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.","Bibliometric analysis; Bibliometrix; Cephalopods; Model species; Science mapping","article; biochemistry; brain; Canada; ecology; Ireland; neurobiology; nonhuman; octopus; Portugal; Spain; Web of Science","","","","","","","Jereb P., Roper C.F.E., Norman M.D., Finn J.K., Cephalopods of the World. An annotated and illustrated catalogue of cephalopod species known to date, Octopods and Vampire Squids, 3, (2014); Doubleday Z.A., Prowse T.A.A., Arkhipkin A., Pierce G.J., Semmens J., Steer M., Leporati S.C., Lourenco S., Quetglas A., Sauer W., Et al., Global proliferation of cephalopods, Curr. Biol, 26, pp. R406-R407, (2016); Clark C., A Review of the global commercial cephalopod fishery, with a focus on apparent expansion, changing environments, and management, (2019); O'Brien C.E., Roumbedakis K., Winkelmann I.E., The current state of cephalopod science and perspectives on the most critical challenges ahead from three early-career researchers, Front. Physiol, 9, (2018); Di Cosmo A., Bertapelle C., Porcellini A., Polese G., Magnitude assessment of adult neurogenesis in the Octopus vulgaris brain using a flow cytometry-based technique, Front. Physiol, 9, (2018); Bertapelle C., Polese G., Di Cosmo A., Enriched environment increases PCNA and PARP1 levels in Octopus vulgaris central nervous system: First evidence of adult neurogenesis in Lophotrochozoa, J. Exp. Zool. Part. Mol. Dev. Evol, 328, pp. 347-359, (2017); Winlow W., Di Cosmo A., Editorial: Sentience, ain, and Anesthesia in Advanced Invertebrates, Front. Physiol, 10, (2019); Juarez O.E., Lopez-Galindo L., Perez-Carrasco L., Lago-Leston A., Rosas C., Di Cosmo A., Galindo-Sanchez C.E., Octopus maya white body show sex-specific transcriptomic profiles during the reproductive phase, with high differentiation in signaling pathways, PLoS ONE, 14, (2019); Winlow W., Polese G., Moghadam H.F., Ahmed I.A., Di Cosmo A., Sense and insensibility—An appraisal of the effects of clinical anesthetics on gastropod and cephalopod molluscs as a step to improved welfare of cephalopods, Front. Physiol, 9, (2018); Maselli V., Xu F., Syed N.I., Polese G., Di Cosmo A., A novel approach to primary cell culture for Octopus vulgaris neurons, Front. Physiol, 9, (2018); Zarrella I., Ponte G., Baldascino E., Fiorito G., Learning and memory in Octopus vulgaris: A case of biological plasticity, Curr. Opin. Neurobiol, 35, pp. 74-79, (2015); Maselli V., Polese G., Al-Soudy A.S., Buglione M., Di Cosmo A., Cognitive stimulation induces differential gene expression in Octopus vulgaris: The key role of protocadherins, Biology, 9, (2020); Winters G.C., Polese G., Di Cosmo A., Moroz L.L., Mapping of neuropeptide Y expression in Octopus brains, J. 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Phys, 64, (2001); Fanelli D., Lariviere V., Researchers’ individual publication rate has not increased in a century, PLoS ONE, 11, (2016); Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the Protection of Animals Used for Scientific Purposes, (2010); Persson O., Glanzel W., Danell R., Inflationary bibliometric values: The role of scientific collaboration and the need for relative indicators in evaluative studies, Scientometrics, 60, pp. 421-432, (2004); Narin F., Globalization of research, scholarly information, and patents—Ten year trends, Ser. Libr, 21, pp. 33-44, (1991); O'Brien C.E., Ponte G., Fiorito G., Octopus. Encycl. Anim. Behav, pp. 142-148, (2019); Falagas M.E., Pitsouni E.I., Malietzis G.A., Pappas G., Comparison of PubMed, Scopus, Web of Science, and Google Scholar: Strengths and weaknesses, FASEB J, 22, pp. 338-342, (2008)","A. Di Cosmo; Department of Biology, University of Naples Federico II, Naples, via Cinthia, 80126, Italy; email: anna.scandurra@unina.it","","MDPI AG","","","","","","20762615","","","","English","Animals","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85107975560" -"Zhang L.; Ling J.; Lin M.","Zhang, Lili (57226160424); Ling, Jie (57226153156); Lin, Mingwei (55363477900)","57226160424; 57226153156; 55363477900","Artificial intelligence in renewable energy: A comprehensive bibliometric analysis","2022","Energy Reports","8","","","14072","14088","16","128","10.1016/j.egyr.2022.10.347","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141248029&doi=10.1016%2fj.egyr.2022.10.347&partnerID=40&md5=d27ffd1a01698658f4bbad7980a1be61","College of Electronics and Information Science, Fujian Jiangxia University, Fujian, Fuzhou, 350108, China; College of Computer and Cyber Security, Fujian Normal University, Fujian, Fuzhou, 350117, China; Fujian Provincial University Engineering Research Center of Big Data Analysis and Application, Fujian Normal University, Fujian, Fuzhou, 350117, China","Zhang L., College of Electronics and Information Science, Fujian Jiangxia University, Fujian, Fuzhou, 350108, China; Ling J., College of Computer and Cyber Security, Fujian Normal University, Fujian, Fuzhou, 350117, China; Lin M., College of Computer and Cyber Security, Fujian Normal University, Fujian, Fuzhou, 350117, China, Fujian Provincial University Engineering Research Center of Big Data Analysis and Application, Fujian Normal University, Fujian, Fuzhou, 350117, China","In recent years, artificial intelligence methods have been widely applied to solve issues related to renewable energy because of their ability to solve nonlinear and complex data structures. In this paper, we provide a comprehensive bibliometric analysis to better understand the evolution of Artificial Intelligence in Renewable Energy (AI&RE) research from 2006 to 2022. This study is performed based on the Web of Science Core Collection Database, and a dataset of 469 publications have been retrieved. This paper uses VOS viewer, CiteSpace, and Bibliometrix to perform bibliometric analysis and science mapping. The analysis results show that China is the most productive and influential country/region, with the widest range of collaborative partners. The study reveals that AI-related technologies can effectively solve issues related to integrating renewable energy with power system, such as solar and wind forecasting, power system frequency analysis and control, and transient stability assessment. In addition, future research trends are discussed. This paper helps scholars to understand the evolution of AI&RE research from a bibliometric perspective and inspires them to think about the field through multiple aspects. © 2022 The Author(s)","Artificial intelligence; Bibliometric analysis; Renewable energy; Visualization","Artificial intelligence; System stability; Weather forecasting; Artificial intelligence methods; Bibliometrics analysis; Citespace; Complex data structures; Energy research; Nonlinear data; Power; Renewable energies; Solar and winds; Web of Science; Renewable energy resources","","","","","Natural Science Foundation of Fujian Province, (2022J01132764)","This work was supported in part by the Fujian Provincial Natural Science Foundation of China under Grant No. 2022J01132764 .","Alsayed M., Cacciato M., Scarcella G., Scelba G., Multicriteria optimal sizing of photovoltaic-wind turbine grid connected systems, IEEE Trans. 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Econ., 25, 3, pp. 369-385, (2019); Zahraee S.M., Hatami M., Bavafa A.A., Ghafourian K., Rohani J.M., Application of statistical taguchi method to optimize main elements in the residential buildings in Malaysia based energy consumption, Appl. Mech. Mater., 606, pp. 265-269, (2014); Zhang K., Liang Q.M., Recent progress of cooperation on climate mitigation: A bibliometric analysis, J. Cleaner Prod., 277, (2020); Zhang Y., Shi X., Zhang H., Cao Y., Terzija V., Review on deep learning applications in frequency analysis and control of modern power system, Int. J. Electr. Power Energy Syst., 136, (2022); Zhang L., Wang J., Niu X., Liu Z., Ensemble wind speed forecasting with multi-objective archimedes optimization algorithm and sub-model selection, Appl. Energy, 301, (2021); Zhong M., Lin M., Bibliometric analysis for economy in COVID-19 pandemic, Heliyon, 8, 9, (2022); Zhou W., Chen J., Huang Y., Co-citation analysis and burst detection on financial bubbles with scientometrics approach, Econ. Res. Ekon. Istrazivanja, 32, 1, pp. 2310-2328, (2019); Zhou X., Li T., Ma X., A bibliometric analysis of comparative research on the evolution of international and Chinese green supply chain research hotspots and frontiers, Environ. Sci. Pollut. Res., 28, 6, pp. 6302-6323, (2021)","M. Lin; College of Computer and Cyber Security, Fujian Normal University, Fuzhou, Fujian, 350117, China; email: linmwcs@163.com","","Elsevier Ltd","","","","","","23524847","","","","English","Energy Rep.","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85141248029" -"Agbo F.J.; Oyelere S.S.; Suhonen J.; Tukiainen M.","Agbo, Friday Joseph (57210111880); Oyelere, Solomon Sunday (57188672243); Suhonen, Jarkko (7006843907); Tukiainen, Markku (56011914400)","57210111880; 57188672243; 7006843907; 56011914400","Scientific production and thematic breakthroughs in smart learning environments: a bibliometric analysis","2021","Smart Learning Environments","8","1","1","","","","214","10.1186/s40561-020-00145-4","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099423632&doi=10.1186%2fs40561-020-00145-4&partnerID=40&md5=9db53dfd473409cee46b46c43a288cf8","School of Computing, University of Eastern Finland, P.O. Box 111, Joensuu, FIN-80101, Finland; Department of Computer Science, Electrical and Space Engineering, Luleå University of Technology, Luleå, Sweden","Agbo F.J., School of Computing, University of Eastern Finland, P.O. Box 111, Joensuu, FIN-80101, Finland; Oyelere S.S., Department of Computer Science, Electrical and Space Engineering, Luleå University of Technology, Luleå, Sweden; Suhonen J., School of Computing, University of Eastern Finland, P.O. Box 111, Joensuu, FIN-80101, Finland; Tukiainen M., School of Computing, University of Eastern Finland, P.O. Box 111, Joensuu, FIN-80101, Finland","This study examines the research landscape of smart learning environments by conducting a comprehensive bibliometric analysis of the field over the years. The study focused on the research trends, scholar’s productivity, and thematic focus of scientific publications in the field of smart learning environments. A total of 1081 data consisting of peer-reviewed articles were retrieved from the Scopus database. A bibliometric approach was applied to analyse the data for a comprehensive overview of the trend, thematic focus, and scientific production in the field of smart learning environments. The result from this bibliometric analysis indicates that the first paper on smart learning environments was published in 2002; implying the beginning of the field. Among other sources, “Computers & Education,” “Smart Learning Environments,” and “Computers in Human Behaviour” are the most relevant outlets publishing articles associated with smart learning environments. The work of Kinshuk et al., published in 2016, stands out as the most cited work among the analysed documents. The United States has the highest number of scientific productions and remained the most relevant country in the smart learning environment field. Besides, the results also showed names of prolific scholars and most relevant institutions in the field. Keywords such as “learning analytics,” “adaptive learning,” “personalized learning,” “blockchain,” and “deep learning” remain the trending keywords. Furthermore, thematic analysis shows that “digital storytelling” and its associated components such as “virtual reality,” “critical thinking,” and “serious games” are the emerging themes of the smart learning environments but need to be further developed to establish more ties with “smart learning”. The study provides useful contribution to the field by clearly presenting a comprehensive overview and research hotspots, thematic focus, and future direction of the field. These findings can guide scholars, especially the young ones in field of smart learning environments in defining their research focus and what aspect of smart leaning can be explored. © 2021, The Author(s).","Bibliometric analysis; Bibliometrix R-package; Biblioshiny; Research trends; Science mapping; Smart learning environments","","","","","","European Commission, EC, (202020); European Commission, EC","","Agbo F.J., Oyelere S.S., Suhonen J., Tukiainen M., Identifying potential design features of a smart learning environment for programming education in Nigeria, International Journal of Learning Technology, 14, 4, pp. 331-354, (2019); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aria M., Cuccurullo C., Biblioshiny blibliometrix for no coders, (2020); Arici F., Yildirim P., Caliklar S., Yilmaz R.M., Research trends in the use of augmented reality in science education: Content and bibliometric mapping analysis, Computers in Education, 142, (2019); Atchison C.J., Bowman L., Vrinten C., Redd R., Pristera P., Eaton J.W., Ward H., Perceptions and behavioural responses of the general public during the COVID-19 pandemic: A cross-sectional survey of UK adults, (2020); Baker R.S., D'Mello S.K., Rodrigo M.M.T., Graesser A.C., Better to be frustrated than bored: The incidence, persistence, and impact of learners’ cognitive–affective states during interactions with three different computer-based learning environments, International Journal of Human-Computer Studies, 68, 4, pp. 223-241, (2010); Cardenas-Robledo L., Pena-Ayal A., Ubiquitous learning: A systematic review, Telematics and Informatics, 35, 5, pp. 1097-1132, (2018); D'mello S., Graesser A., AutoTutor and affective AutoTutor: Learning by talking with cognitively and emotionally intelligent computers that talk back, ACM Transactions on Interactive Intelligent Systems (TiiS), 2, 4, pp. 1-39, (2013); Esfahani H., Tavasoli K., Jabbarzadeh A., Big data and social media: A scientometrics analysis, International Journal of Data and Network Science, 3, 3, pp. 145-164, (2019); Gilani E., Salimi D., Jouyandeh M., Tavasoli K., Wong W., A trend study on the impact of social media in decision making, International Journal of Data and Network Science, 3, 3, pp. 201-222, (2019); Grant J., Cottrell R., Cluzeau F., Fawcett G., Evaluating “payback” on biomedical research from papers cited in clinical guidelines: Applied bibliometric study, BMJ [British Medical Journal], 320, 7242, pp. 1107-1111, (2000); Hammad R., Ludlow D., Towards a smart learning environment for smart city governance, Proceedings of the 9th international conference on utility and cloud computing, pp. 185-190, (2016); Harris C., Dousay T.A., Hall C., Srinivasan S., Srinivasan R., Trashbots: Coding with creativity in a middle grades computer science camp, Society for Information Technology & Teacher Education International Conference, pp. 1117-1120, (2020); Heinemann C., Uskov V.L., Smart University: Literature review and creative analysis, Smart universities. SEEL 2017. Smart innovation, systems and technologies, (2018); Heradio R., De La Torre L., Galan D., Cabrerizo F.J., Herrera-Viedma E., Dormido S., Virtual and remote labs in education: A bibliometric analysis, Computers in Education, 98, pp. 14-38, (2016); Hwang G.J., Definition, framework and research issues of smart learning environments-a context-aware ubiquitous learning perspective, Smart Learning Environments, 1, 1, (2014); Kim T., Cho J.Y., Lee B.G., Evolution to smart learning in public education: A case study of Korean public education, In the IFIP WG 3.4 International Conference on Open and Social Technologies for Networked Learning, pp. 170-178, (2012); Kinshuk C.N.S., Cheng I.L., Chew S.W., Evolution is not enough: Revolutionizing current learning environments to smart learning environments, International Journal of Artificial Intelligence in Education, 26, 2, pp. 561-581, (2016); Labib A.E., Canos J.H., Penades M.C., On the way to learning style models integration: A Learner's characteristics ontology, Computers in Human Behavior, 73, pp. 433-445, (2017); Laine H.T., Joy M., Survey on context-aware pervasive learning environments, International Journal of Interactive Mobile Technologies, 3, 1, pp. 70-76, (2009); Lazonder A.W., Harmsen R., Meta-analysis of inquiry-based learning: Effects of guidance, Review of Educational Research, 86, 3, pp. 681-718, (2016); Lei C.U., Wan K., Man K.L., Developing a smart learning environment in universities via cyber-physical systems, Procedia Computer Science, 17, pp. 583-585, (2013); Li J., Antonenko P.D., Wang J., Trends and issues in multimedia learning research in 1996-2016: A bibliometric analysis, Educational Research Review, 28, (2019); Malmberg J., Jarvela S., Jarvenoja H., Capturing temporal and sequential patterns of self-, co-, and socially shared regulation in the context of collaborative learning, Contemporary Educational Psychology, 49, pp. 160-174, (2017); Mavroudi A., Giannakos M., Krogstie J., Supporting adaptive learning pathways through the use of learning analytics: Developments, challenges and future opportunities, Interactive Learning Environments, 26, 2, pp. 206-220, (2018); McIntosh K., Herman K., Sanford A., McGraw K., Florence K., Teaching transitions: Techniques for promoting success between lessons, Teaching Exceptional Children, 37, 1, pp. 32-38, (2004); Molina-Carmona R., Villagr-Arnedo C., Smart learning, ACM international conference proceeding series, pp. 645-647, (2018); Ouf S., Abd Ellatif M., Salama S.E., Helmy Y., A proposed paradigm for smart learning environment based on semantic web, Computers in Human Behavior, 72, pp. 796-818, (2017); Potkonjak V., Gardner M., Callaghan V., Mattila P., Guetl C., Petrovic V.M., Jovanovic K., Virtual laboratories for education in science, technology, and engineering: A review, Computers in Education, 95, pp. 309-327, (2016); Prell C., Hubacek K., Reed M., Stakeholder analysis and social network analysis in natural resource management, Society and Natural Resources, 22, 6, pp. 501-518, (2009); Reimers F.M., Schleicher A., A framework to guide an education response to the COVID-19 pandemic of 2020, (2020); Shen C.W., Ho J.T., Technology-enhanced learning in higher education: A bibliometric analysis with latent semantic approach, Computers in Human Behavior, 104, (2020); Song Y., Et al., Exploring two decades of research on classroom dialogue by using bibliometric analysis, Computers in Education, 137, pp. 12-31, (2019); Sosteric M., Hesemeier S., When is a learning object not an object: A first step towards a theory of learning objects, The International Review of Research in open and distributed learning, 3, 2, (2002); Tikhomirov V., Dneprovskaya N., Yankovskaya E., Three dimensions of smart education, Smart education and smart e-learning. Smart innovation, systems and technologies, (2015); Toivonen T., Jormanainen I., Montero C.S., Alessandrini A., Et al., Innovative maker movement platform for K-12 education as a smart learning environment, Challenges and solutions in smart learning, (2018); Tomczyk L., Oyelere S.S., Puentes A., Sanchez-Castillo G., Munoz D., Simsek B., Demirhan G., Flipped learning, digital storytelling as the new solutions in adult education and school pedagogy, Adult Education 2018 - Transformation in the Era of Digitization and Artificial Intelligence, pp. 69-83, (2019); Tripathi M., Kumar S., Sonker S.K., Babbar P., Occurrence of author keywords and keywords plus in social sciences and humanities research: A preliminary study, COLLNET Journal of Scientometrics and Information Management, 12, 2, pp. 215-232, (2018); Uskov V.L., Bakken J.P., Pandey A., Singh U., Yalamanchili M., Penumatsa A., Smart University taxonomy: Features, components, systems, Smart education and e-learning 2016. Smart innovation, systems and technologies, (2016); Uskov V.L., Bakken J.P., Penumatsa A., Heinemann C., Rachakonda R., Smart pedagogy for smart universities, Smart education and e-learning 2017. SEEL 2017. Smart innovation, systems and technologies, (2018); Waheed H., Hassan S., Aljohani N., Wasif M., Bibliometric perspective of learning analytics research landscape, Behavior & Information Technology, 37, 10-11, pp. 941-957, (2018); Wang H., Ming Z., Zhang M., He J., Cheng L., Qian Z., The research status and hotspots in the domain of smart learning in China from 2012–2019, (2020); Zacharia Z.C., Manoli C., Xenofontos N., De Jong T., Pedaste M., van Riesen S.A., Et al., Identifying potential types of guidance for supporting student inquiry when using virtual and remote labs in science: A literature review, Educational Technology Research and Development, 63, 2, pp. 257-302, (2015); Zervas P., Sergis S., Sampson D.G., Fyskilis S., Towards competence-based learning design driven remote and virtual labs recommendations for science teachers, Technology, Knowledge and Learning, 20, 2, pp. 185-199, (2015); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","F.J. Agbo; School of Computing, University of Eastern Finland, Joensuu, P.O. Box 111, FIN-80101, Finland; email: fridaya@uef.fi","","Springer","","","","","","21967091","","","","English","Smart Learn. Environ.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85099423632" -"Ingale K.K.; Paluri R.A.","Ingale, Kavita Karan (57220637497); Paluri, Ratna Achuta (57189712737)","57220637497; 57189712737","Financial literacy and financial behaviour: a bibliometric analysis","2022","Review of Behavioral Finance","14","1","","130","154","24","121","10.1108/RBF-06-2020-0141","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097500261&doi=10.1108%2fRBF-06-2020-0141&partnerID=40&md5=f0a454a391fce549223f3043432221af","Symbiosis International (Deemed University), Pune, India; Symbiosis Institute of Operations Management, Nashik, India","Ingale K.K., Symbiosis International (Deemed University), Pune, India; Paluri R.A., Symbiosis International (Deemed University), Pune, India, Symbiosis Institute of Operations Management, Nashik, India","Purpose: Numerous exploratory, conceptual and empirical enquiries on financial behaviour and literacy have been conducted in the areas of economics, finance, business and management. However, no attempt was made to present a comprehensive science mapping of the area so far. Hence, the study intends to elicit the trend in the research field through synthesis of knowledge structures. Design/methodology/approach: Bibliometric analysis in the field of financial literacy and financial behaviour was performed on a sample of 1,138 documents based on a scientific search strategy run on the Web of Science database for the period 1985–2020. Biblioshiny, which is a web-based application included in Bibliometrix package developed in R-language (Ariaa and Cuccurullo, 2017), was used for the study. With the help of automated workflow in the software, prominent journals, authors, countries, articles, themes were identified; and citation, co-citation and social network analysis were conducted. Findings: Results show that the themes of financial literacy and financial behaviour have evolved over a period of time as an interdisciplinary field. In the initial stages, researchers focused on demographic and socio-economic determinants, but gradually the field embraced topics like behavioural and psychological constructs influencing financial behaviour. Along with conceptual structure, this research reveals the intellectual and social structure of the domain. This study provides important insights on areas that need further investigation. Research limitations/implications: The current research is a bibliometric analysis and hence limitations related to such studies are applicable. For future researchers to derive a strong conceptual framework, a systematic review of literature would be helpful. Science mapping for this study is limited to the Web of Science database owing to its wider coverage of good quality journals, structured formats which are compatible with the Bibliometrix software. Practical implications: The current study provides important insights on financial literacy and financial behaviour and their inter-linkages. It highlights the most addressed issues in the area and leads towards the prospective areas for research. It informs the future researchers about the emergent themes, contexts and possibilities of collaborations in this area by revealing social and intellectual structure of the domain. Social implications: The paper can provide important insights for policy formulation in the areas of financial education and literacy. Originality/value: There has been lot of conceptual and empirical work done in the past, across countries, spanning the disciplines such as economics, finance, psychology and consumer behaviour. A major contribution of this study is that it consolidates fragmented literature in the area, highlights significant sources, authors and documents, while exploring the relation between financial literacy and financial behaviour. © 2020, Emerald Publishing Limited.","Bibliometric analysis; Bibliometrix; Financial behaviour; Financial literacy; Household finance; Science mapping","","","","","","","","Ajzen I., The theory of planned behavior, Organizational Behavior and Human Decision Processes, 50, 2, pp. 179-211, (1991); Ariaa M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bedi H.S., Karn A.K., Kaur G.P., Duggal R., Financial literacy–A Bibliometric analysis, Our Heritage, 67, 10, pp. 1042-1054, (2019); Brown S., Gray D., Household finances and well-being in Australia: an empirical analysis of comparison effects, Journal of Economic Psychology, 53, pp. 17-36, (2016); Bruggen E.C., Hogreve J., Holmlund M., Kabadayi S., Lofgren M., Financial well-being: a conceptualization and research agenda, Journal of Business Research, 79, pp. 228-237, (2017); Calcagno R., Monticone C., Financial literacy and the demand for financial advice, Journal of Banking and Finance, 50, pp. 363-380, (2015); Campbell J., Household finance, The Journal of Finance, 61, 4, pp. 1553-1604, (2006); Carlsson H., Larsson S., Svensson L., Astrom F., Consumer credit behavior in the digital context: a Bibliometric analysis and literature review, Journal of Financial Counseling and Planning, 28, 1, pp. 76-94, (2017); Carvalho G., Cruz J., Carvalho H., Duclos L., Stankowitz R., Innovativeness measures: a Bibliometric review and a classification proposal, International Journal of Innovation Science, 9, 1, pp. 81-101, (2017); Chen X., Lun Y., Yan J., Hao T., Weng H., Discovering thematic change and evolution of utilizing social media for healthcare research, BMC Medical Informatics and Decision Making, 19, 2, (2019); Cobo M., Lopez-Herrera A., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: a practical application to the fuzzy sets theory field, Journal of Informetrics, 5, 1, pp. 146-166, (2011); Della Corte V., Del Gaudio G., Sepe F., Sciarelli F., Sustainable tourism in the open innovation realm: a Bibliometric Analysis, Sustainability, 11, 21, (2019); Devlin J.F., Consumer evaluation and competitive advantage in retail financial services: a research agenda, European Journal of Marketing, 35, 5-6, pp. 639-660, (2001); Edge D., Quantitative measures of communication in science: a critical review, History of Science, 17, 36, pp. 102-134, (1979); Egghe L., Rousseau R., Introduction to Informetrics. 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Van Rooij M.C., Lusardi A., Alessie R.J., Financial literacy, retirement planning and household wealth, The Economic Journal, 122, 560, pp. 449-478, (2012); Xu X., Chen X., Jia F., Brown S., Gong Y., Xu Y., Supply chain finance: a systematic literature review and Bibliometric analysis, International Journal of Production Economics, 204, pp. 160-173, (2018); Zhang J., Yu Q., Zheng F., Long C., Lu Z., Duan Z., Comparing keywords plus of WOS and author keywords: a case study of patient adherence research, Journal of the Association for Information Science and Technology, 67, 4, pp. 967-972, (2016); Zhang D., Zhang Z., Managi S., A Bibliometric analysis on green finance: current status, development, and future directions, Finance Research Letters, 29, pp. 425-430, (2019); Abad-Segura E., Gonzalez-Zamar M.D., Effects of financial education and financial literacy on creative entrepreneurship: a worldwide research, Education Sciences, 9, 3, (2019); De Abreu E.S., Kimura H., Sobreiro V.A., What is going on with studies on banking efficiency?, Research in International Business and Finance, 47, pp. 195-219, (2019)","R.A. Paluri; Symbiosis International (Deemed University), Pune, India; email: ratna.paluri@siom.in","","Emerald Group Holdings Ltd.","","","","","","19405979","","","","English","Rev. Behav. Financ.","Review","Final","","Scopus","2-s2.0-85097500261" -"Donthu N.; Kumar S.; Pandey N.","Donthu, Naveen (6602336941); Kumar, Satish (57992552600); Pandey, Nitesh (57211577722)","6602336941; 57992552600; 57211577722","A retrospective evaluation of Marketing Intelligence and Planning: 1983–2019","2021","Marketing Intelligence and Planning","39","1","","48","73","25","70","10.1108/MIP-02-2020-0066","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085984124&doi=10.1108%2fMIP-02-2020-0066&partnerID=40&md5=9c22b872c5d2643d0bf37dab6b047d3e","Georgia State University, Atlanta, GA, United States; Malaviya National Institute of Technology Jaipur, Jaipur, India","Donthu N., Georgia State University, Atlanta, GA, United States; Kumar S., Malaviya National Institute of Technology Jaipur, Jaipur, India; Pandey N., Malaviya National Institute of Technology Jaipur, Jaipur, India","Purpose: The purpose of this study is to map the development of articles published, citations, and themes of Marketing Intelligence and Planning (MIP) over the 37-year period of 1983–2019. Design/methodology/approach: This study uses the Scopus database to identify the most-cited MIP articles and most-included authors, institutions and countries in MIP. The study uses bibliometric indicators, as well as tools such as bibliographic coupling, performance analysis and science mapping, to analyze the publication and citation structure of MIP. The study provides a temporal analysis of MIP publishing across different time periods. Findings: MIP has an average publication of 43 articles each year, and the number of citations has grown substantially since it started publication. Although contributors to the journal come from around the globe, they most often are affiliated with the United Kingdom, United States, and Australia. Bibliographic coupling of documents reveals that the journal's primary focus has been on issues such as marketing planning, marketing theory, consumer behavior, global marketing, customer relationship management, customer service and branding. Co-authorship analysis reveals that the journal's collaborative network has grown. Research limitations/implications: This study uses data from the Scopus database, and any limitations of the database have implications for the findings. Originality/value: First analysis of this kind of papers published in MIP © 2020, Emerald Publishing Limited.","Bibliometrix; Citation analysis; Gephi; H-index; Keyword analysis; Marketing intelligence and planning; Scopus; VOSviewer","","","","","","","","Abdullah Z., Shahrina N., Abdul Aziz Y., Building a unique online corporate identity, Marketing Intelligence & Planning, 31, 5, pp. 451-471, (2013); Akturan U., Tezcan N., Mobile banking adoption of the youth market: perceptions and intentions, Marketing Intelligence and Planning, 30, 4, pp. 444-459, (2012); Al-Hyari K., Al-Weshah G., Alnsour M., Barriers to internationalisation in SMEs: evidence from Jordan, Marketing Intelligence and Planning, 30, 2, pp. 188-211, (2012); Al-Sulaiti K.I., Baker M.J., Country of origin effects: a literature review, Marketing Intelligence and Planning, 16, 3, pp. 150-199, (1998); Alonso S., Cabrerizo F.J., Herrera-Viedma E., Herrera F., h-Index: a review focused in its variants, computation and standardization for different scientific fields, Journal of Informetrics, 3, 4, pp. 273-289, (2009); Altintas M.H., Tokol T., Cultural openness and consumer ethnocentrism: an empirical analysis of Turkish consumers, Marketing Intelligence and Planning, 25, 4, pp. 308-325, (2007); Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Atilgan E., Aksoy S., Akinci S., Determinants of the brand equity: a verification approach in the beverage industry in Turkey, Marketing Intelligence and Planning, 23, 3, pp. 237-248, (2005); Aydin S., Ozer G., Arasil O., Customer loyalty and the effect of switching costs as a moderator variable. A case in the Turkish mobile phone market, Marketing Intelligence and Planning, 23, 1, pp. 89-103, (2005); Bastian M., Heymann S., Jacomy M., Gephi: an open source software for exploring and manipulating networks, Proceedings of the Third International ICWSM Conference (2009), pp. 361-362, (2009); Beverland M., Dobele A., Farrelly F., The viral marketing metaphor explored through Vegemite, Marketing Intelligence and Planning, 33, 5, pp. 656-674, (2015); Binsardi A., Ekwulugo F., International marketing of British education: research on the students' perception and the UK market penetration, Marketing Intelligence and Planning, 21, 5, pp. 318-327, (2003); Blankson C., Stokes D., Marketing practices in the UK small business sector, Marketing Intelligence and Planning, 20, 1, pp. 49-61, (2002); Blankson C., Motwani J.G., Levenburg N.M., Understanding the patterns of market orientation among small businesses, Marketing Intelligence and Planning, 24, 6, pp. 572-590, (2006); Broadus R.N., Toward a definition of ‘bibliometrics’, Scientometrics, 12, 5-6, pp. 373-379, (1987); Brown S., Retro‐marketing: yesterday's tomorrows, today!, Marketing Intelligence and Planning, 17, 7, pp. 363-376, (1999); Civi E., Knowledge management as a competitive asset: a review, Marketing Intelligence and Planning, 18, 4, pp. 166-174, (2000); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: a practical application to the Fuzzy Sets Theory field, Journal of Informetrics, 5, 1, pp. 146-166, (2011); Comerio N., Strozzi F., Tourism and its economic impact: a literature review using bibliometric tools, Tourism Economics, 25, 1, pp. 109-131, (2019); Crane D., Social structure in a group of Scientists: a test of the ‘invisible college’, American Sociological Review, 34, 3, pp. 335-352, (1969); Dibb S., Market segmentation: strategies for success, Marketing Intelligence and Planning, 16, 7, pp. 394-406, (1998); Donthu N., Kumar S., Pattnaik D., Forty-five years of journal of business research: a bibliometric analysis, Journal of Business Research, 109, 1, pp. 1-14, (2020); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: how great is the impact?, Scientometrics, 105, 3, pp. 1809-1831, (2015); Erdogan B.Z., Kitchen P.J., Managerial mindsets and the symbiotic relationship between sponsorship and advertising, Marketing Intelligence and Planning, 16, 6, pp. 369-374, (1998); Fan Y., The globalisation of Chinese brands, Marketing Intelligence and Planning, 24, 4, pp. 365-379, (2006); Foster B.D., Cadogan J.W., Relationship selling and customer loyalty: an empirical investigation, Marketing Intelligence and Planning, 18, 4, pp. 185-199, (2000); Gilmore A., Carson D., Grant K., SME marketing in practice, Marketing Intelligence and Planning, 19, 1, pp. 6-11, (2001); Harker M.J., Relationship marketing defined? An examination of current relationship marketing definitions, Marketing Intelligence and Planning, 17, 1, pp. 13-20, (1999); Hartmann P., Apaolaza Ibanez V., Forcada Sainz F.J., Green branding effects on attitude: functional versus emotional positioning strategies, Marketing Intelligence and Planning, 23, 1, pp. 9-29, (2005); Hoffman D.L., Holbrook M.B., The intellectual structure of consumer research: a bibliometric study of author cocitations in the first 15 Years of the journal of consumer research, Journal of Consumer Research, 19, 4, pp. 505-517, (1993); Huang Y.C., Yang M., Wang Y.C., Effects of green brand on green purchase intention, Marketing Intelligence and Planning, 32, 3, pp. 250-268, (2014); Ibrahim E.E., Gill J., A positioning strategy for a tourist destination, based on analysis of customers' perceptions and satisfactions, Marketing Intelligence and Planning, 23, 2, pp. 172-188, (2005); Islam J.U., Rahman Z., Hollebeek L.D., Personality factors as predictors of online consumer engagement: an empirical investigation, Marketing Intelligence and Planning, 35, 4, pp. 510-528, (2017); Jalilvand M.R., Samiei N., The effect of electronic word of mouth on brand image and purchase intention: an empirical study in the automobile industry in Iran, Marketing Intelligence and Planning, 30, 4, pp. 460-476, (2012); Jamal A., Goode M., Consumers and brands: a study of the impact of self-image congruence on brand preference and satisfaction, Marketing Intelligence and Planning, 19, 7, pp. 482-492, (2001); Jin S.A.A., The potential of social media for luxury brand management, Marketing Intelligence and Planning, 30, 7, pp. 687-699, (2012); Jones P., Clarke-Hill C., Hillier D., Comfort D., The benefits, challenges and impacts of radio frequency identification technology (RFID) for retailers in the UK, Marketing Intelligence and Planning, 23, 4, pp. 395-402, (2005); Jones P., Comfort D., Hillier D., What's in store? Retail marketing and corporate social responsibility, Marketing Intelligence and Planning, 25, 1, pp. 17-30, (2007); Jones P., Clarke-Hill C., Comfort D., Hillier D., Marketing and sustainability, Marketing Intelligence and Planning, 26, 2, pp. 123-130, (2008); Kessler M.M., Bibliographic coupling between scientific articles, American Documentation, 14, 1, pp. 123-131, (1963); Kinra N., The effect of country-of-origin on foreign brand names in the Indian market, Marketing Intelligence and Planning, 24, 1, pp. 15-30, (2006); Koch A.J., Selecting overseas markets and entry modes: two decision processes or one?, Marketing Intelligence and Planning, 19, 1, pp. 65-75, (2001); Kumar R.S., Dash S., Purwar P.C., The nature and antecedents of brand equity and its dimensions, Marketing Intelligence and Planning, 31, 2, pp. 141-159, (2013); Kumar P., Sharma A., Salo J., A bibliometric analysis of extended key account management literature, Industrial Marketing Management, 82, January, pp. 276-292, (2019); Lee K., Opportunities for green marketing: young consumers, Marketing Intelligence and Planning, 26, 6, pp. 573-586, (2008); Lewis B.R., Mitchell V.W., Defining and measuring the quality of customer service, Marketing Intelligence and Planning, 8, 6, pp. 11-17, (1990); Malhotra N.K., Wu L., Whitelock J., An overview of the first 21 years of research in the International Marketing Review, 1983-2003, International Marketing Review, 22, 4, pp. 391-398, (2005); Martinez-Lopez F.J., Merigo J.M., Valenzuela-Fernandez L., Nicolas C., Fifty years of the European Journal of Marketing: a bibliometric analysis, European Journal of Marketing, 52, 1-2, pp. 439-468, (2018); Mccole P., Refocusing marketing to reflect practice: the changing role of marketing for business, Marketing Intelligence and Planning, 22, 5, pp. 531-539, (2004); Mcnaughton R.B., The export mode decision-making process in small knowledge-intensive firms, Marketing Intelligence and Planning, 19, 1, pp. 12-20, (2001); Mohammed A.H., Ward T., The effect of automated service quality on Australian banks' financial performance and the mediating role of customer satisfaction, Marketing Intelligence and Planning, 24, 2, pp. 127-147, (2006); Molinillo S., Japutra A., Nguyen B., Chen C.H.S., Responsible brands vs active brands? An examination of brand personality on brand awareness, brand trust, and brand loyalty, Marketing Intelligence and Planning, 35, 2, pp. 166-179, (2017); Mourad M., Ennew C., Kortam W., Brand equity in higher education, Marketing Intelligence and Planning, 29, 4, pp. 403-420, (2011); Ndubisi N.O., Effect of gender on customer loyalty: a relationship marketing approach, Marketing Intelligence and Planning, 24, 1, pp. 48-61, (2006); Ndubisi N.O., Relationship marketing and customer loyalty, Marketing Intelligence and Planning, 25, 1, pp. 98-106, (2007); Ngai E.W.T., Customer relationship management research (1992-2002): an academic literature review and classification, Marketing Intelligence and Planning, 23, 6, pp. 582-605, (2005); Okumus B., Koseoglu M.A., Ma F., Food and gastronomy research in tourism and hospitality: a bibliometric analysis, International Journal of Hospitality Management, 73, 1, pp. 64-74, (2018); O'Malley L., Can loyalty schemes really build loyalty?, Marketing Intelligence and Planning, 16, 1, pp. 47-55, (1998); Patterson M., Direct marketing in postmodernity: neo-tribes and direct communications, Marketing Intelligence and Planning, 16, 1, pp. 68-74, (1998); Pesta B., Fuerst J., Kirkegaard E., Bibliometric keyword analysis across seventeen years (2000–2016) of intelligence articles, Journal of Intelligence, 6, 4, pp. 46-57, (2018); Rafiq M., Ahmed P.K., Using the 7Ps as a generic marketing mix, Marketing Intelligence and Planning, 13, 9, pp. 4-15, (1995); Rashid S., Ghose K., Organisational culture and the creation of brand identity: retail food branding in new markets, Marketing Intelligence and Planning, 33, 1, pp. 2-19, (2015); Rowley J., Williams C., The impact of brand sponsorship of music festivals, Marketing Intelligence and Planning, 26, 7, pp. 781-792, (2008); Rowley J., Kupiec-Teahan B., Leeming E., Customer community and co-creation: a case study, Marketing Intelligence and Planning, 25, 2, pp. 136-146, (2007); Shaw D., Clarke I., Belief formation in ethical consumer groups: an exploratory study, Marketing Intelligence and Planning, 17, 2, pp. 109-120, (1999); Shi X., Shan X., Cross-cultural impact on financial companies' online brand personality, Marketing Intelligence and Planning, 37, 5, pp. 482-496, (2019); Shoham A., Rose G.M., Kropp F., Market orientation and performance: a meta-analysis, Marketing Intelligence and Planning, 23, 5, pp. 435-454, (2005); Srivastava R.K., Understanding brand identity confusion, Marketing Intelligence and Planning, 29, 4, pp. 340-352, (2011); Tam J.L.M., The moderating role of perceived risk in loyalty intentions: an investigation in a service context, Marketing Intelligence and Planning, 30, 1, pp. 33-52, (2012); Tsimonis G., Dimitriadis S., Brand strategies in social media, Marketing Intelligence and Planning, 32, 3, pp. 328-344, (2014); Valenzuela L.M., Merigo J.M., Johnston W.J., Nicolas C., Jaramillo J.F., Thirty years of the journal of business and industrial Marketing: a bibliometric, Journal of Business and Industrial Marketing, 31, 1, pp. 1-17, (2017); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Wallin J.A., Bibliometric methods: pitfalls and possibilities, Basic and Clinical Pharmacology and Toxicology, 97, 5, pp. 261-275, (2005); Waltman L., Van Eck N.J., A smart local moving algorithm for large-scale modularity-based community detection, European Physical Journal B, 86, 11, (2013); Weinberg B.H., Bibliographic coupling: a review, Information Storage and Retrieval, 10, 5-6, pp. 189-196, (1974); Woodruffe H.R., Compensatory consumption: why women go shopping when they're fed up and other stories, Marketing Intelligence and Planning, 15, 7, pp. 325-334, (1997); Wright S., Pickton D.W., Callow J., Competitive intelligence in UK firms: a typology, Marketing Intelligence and Planning, 20, 6, pp. 349-360, (2002); Yeniyurt S., A literature review and integrative performance measurement framework for multinational companies, Marketing Intelligence and Planning, 21, 3, pp. 134-142, (2003); Zou X., Yue W.L., Vu H.L., Visualization and analysis of mapping knowledge domain of road safety studies, Accident Analysis and Prevention, 118, 1, pp. 131-145, (2018); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","N. Donthu; Georgia State University, Atlanta, United States; email: ndonthu@gsu.edu","","Emerald Group Holdings Ltd.","","","","","","02634503","","","","English","Mark. Intell. Plann.","Article","Final","","Scopus","2-s2.0-85085984124" -"Bakır M.; Özdemir E.; Akan Ş.; Atalık Ö.","Bakır, Mahmut (57218704775); Özdemir, Emircan (57222382021); Akan, Şahap (57218704672); Atalık, Özlem (55588835300)","57218704775; 57222382021; 57218704672; 55588835300","A bibliometric analysis of airport service quality","2022","Journal of Air Transport Management","104","","102273","","","","68","10.1016/j.jairtraman.2022.102273","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85135942713&doi=10.1016%2fj.jairtraman.2022.102273&partnerID=40&md5=54ecf8151d2c2a3594dcbc63e9ed07b6","Department of Aviation Management, Samsun University, Istiklal Denizevleri Str., Samsun, 55420, Turkey; Department of Aviation Management, Eskisehir Technical University, PO Box 26555, Eskisehir, Turkey; Department of Civil Aviation Management, Anadolu University, PO Box 26170, Eskisehir, Turkey","Bakır M., Department of Aviation Management, Samsun University, Istiklal Denizevleri Str., Samsun, 55420, Turkey; Özdemir E., Department of Aviation Management, Eskisehir Technical University, PO Box 26555, Eskisehir, Turkey; Akan Ş., Department of Civil Aviation Management, Anadolu University, PO Box 26170, Eskisehir, Turkey; Atalık Ö., Department of Aviation Management, Eskisehir Technical University, PO Box 26555, Eskisehir, Turkey","Airports have evolved into key business centers in the last four decades, serving a variety of business models in addition to providing transportation infrastructure. Additionally, service quality, which is critical for airports to maintain a competitive edge, is a major area of research in the aviation literature. This study aims to analyze the existing literature on airport service quality through the bibliometric analysis method and to present a perspective on the literature's trajectory. Science mapping techniques and performance analysis were applied in this process. R-based Bibliometrix software was used to investigate 100 studies indexed in the Web of Science (WoS) database between 1975 and 2020. Research findings show that the Journal of Air Transport Management leads the literature in terms of publication performance. Researchers from China offer the highest contribution to the literature as a country. In addition, service quality research has largely resulted from collaboration networks. It is expected that an understanding of the research themes that emerge from the scientific mapping technique will guide researchers. © 2022 Elsevier Ltd","Airport; Bibliometric analysis; Bibliometrix; Service quality; Web of science","China; air transportation; airport; service quality; transportation infrastructure; transportation planning","","","","","","","ACI World data reveals COVID-19's impact on world's busiest airports, (2021); ACI introduces new Airport Service Quality questions related to COVID-19, (2020); ACI releases new research paper analyzing the influence of customer service quality on airports' non-aeronautical revenue, (2016); Adler N., Berechman J., Measuring airport quality from the airlines’ viewpoint: an application of data envelopment analysis, Transp. Pol., 8, pp. 171-181, (2001); Ahmad T., Murad M.A., Baig M., Hui J., Research trends in COVID-19 vaccine: a bibliometric analysis, Hum. Vaccines Immunother., 17, pp. 2367-2372, (2021); Aksit Asik N., Yerli ve Yabancı Yolcuların Havalimanı Hizmet Kalitesi Algıları: İstanbul Havalimanı Örneği, J. Tour. Gastron. Stud., 7, pp. 2612-2629, (2019); Aldemir H.O., Sengur F.K., Academic foundations of air transportation research in an emerging country, Int. J. Aviat. Syst. Oper. Train., 4, pp. 15-27, (2017); Ali F., Kim W.G., Ryu K., The effect of physical environment on passenger delight and satisfaction: moderating effect of national identity, Tour. Manag., 57, pp. 213-224, (2016); Antwi C.O., Ren J., Owusu-Ansah W., Mensah H.K., Aboagye M.O., Airport self-service technologies, passenger self-concept, and behavior: an attributional view, Sustain. Times, 13, pp. 1-18, (2021); Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, J. Inf., 11, pp. 959-975, (2017); Arif M., Gupta A., Williams A., Customer service in the aviation industry - an exploratory analysis of UAE airports, J. Air Transport. Manag., 32, pp. 1-7, (2013); Atalik O., Voice of Turkish customer: importance of expectations and level of satisfaction at airport facilities, Rev. Eur. Stud., 1, pp. 61-67, (2009); Bakir M., Akan S., Ozdemir E., Nguyen P.-H., Tsai J.-F., Pham H.-A., How to achieve passenger satisfaction in the airport? Findings from regression analysis and necessary condition analysis approaches through online airport reviews, Sustainability, 14, pp. 1-20, (2022); Bamel U., Pereira V., Del Giudice M., Temouri Y., The extent and impact of intellectual capital research: a two decade analysis, J. Intellect. Cap., 23, pp. 375-400, (2022); Barakat H., Yeniterzi R., Martin-Domingo L., Applying deep learning models to twitter data to detect airport service quality, J. Air Transport. Manag., 91, (2021); Barbosa M.L.D.O., Galembeck E., Mapping research on biochemistry education: Abibliometric analysis, Biochem. Mol. Biol. Educ., 50, pp. 201-215, (2022); Batouei A., Iranmanesh M., Mustafa H., Nikbin D., Ping T.A., Components of airport experience and their roles in eliciting passengers' satisfaction and behavioural intentions, Res. Transp. Bus. Manag., 37, (2020); Bellizzi M.G., dell'Olio L., Eboli L., Forciniti C., Mazzulla G., Passengers' expectations on airlines' services: design of a stated preference survey and preliminary outcomes, Sustain. Times, 12, (2020); Bellizzi M.G., Eboli L., Mazzulla G., Air transport service quality factors: a systematic literature review, Transport. Res. Procedia, 45, pp. 218-225, (2020); Bergiante N.C.R., Santos M.P.S., Espirito Santo R.A., Bibliometric study of the relationship between business model and air transport, Scientometrics, 105, pp. 941-958, (2015); Bezerra G.C.L., Gomes C.F., Antecedents and consequences of passenger satisfaction with the airport, J. Air Transport. Manag., 83, (2020); Bezerra G.C.L., Gomes C.F., Determinants of passenger loyalty in multi-airport regions: implications for tourism destination, Tourism Manag. Perspect., 31, pp. 145-158, (2019); Bezerra G.C.L., Gomes C.F., Measuring airport service quality: a multidimensional approach, J. Air Transport. Manag., 53, pp. 85-93, (2016); Bezerra G.C.L., Gomes C.F., The effects of service quality dimensions and passenger characteristics on passenger's overall satisfaction with an airport, J. Air Transport. Manag., 44, pp. 77-81, (2015); Bhukya R., Paul J., Kastanakis M., Robinson S., Forty years of European Management Journal: a bibliometric overview, Eur. Manag. J., (2021); Blondel V.D., Guillaume J.L., Lambiotte R., Lefebvre E., Fast unfolding of communities in large networks, J. Stat. Mech. Theor. Exp., (2008); Bogicevic V., Yang W., Bilgihan A., Bujisic M., Airport service quality drivers of passenger satisfaction, Tour. Rev., 68, pp. 3-18, (2013); Bogicevic V., Yang W., Cobanoglu C., Bilgihan A., Bujisic M., Traveler anxiety and enjoyment: the effect of airport environment on traveler's emotions, J. Air Transport. Manag., 57, pp. 122-129, (2016); Bornmann L., Haunschild R., Mutz R., Growth rates of modern science: a latent piecewise growth curve approach to model publication numbers from established and new literature databases, Humanit. Soc. Sci. Commun., 8, pp. 1-15, (2021); Number of U.S. Airports, (2021); Cancino C., Merigo J.M., Coronado F., Dessouky Y., Dessouky M., Forty years of computers & industrial engineering: a bibliometric analysis, Comput. Ind. Eng., 113, pp. 614-629, (2017); (2017); de Carvalho R.C., de Medeiros D.D., Assessing quality of air transport service: a comparative analysis of two evaluation models, Curr. Issues Tourism, 24, pp. 1123-1138, (2021); Choi J.H., Changes in airport operating procedures and implications for airport strategies post-COVID-19, J. Air Transport. Manag., 94, (2021); Chung K.H., Cox R.A.K., Mitchell J.B., Citation patterns in the finance literature, Financ. Manag., 30, pp. 99-118, (2001); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: a practical application to the Fuzzy Sets Theory field, J. Inf., 5, pp. 146-166, (2011); Cobo M.J., Martinez M.A., Gutierrez-Salcedo M., Fujita H., Herrera-Viedma E., 25 years at Knowledge-Based Systems: a bibliometric analysis, Knowl. Base Syst., 80, pp. 3-13, (2015); Comerio N., Strozzi F., Tourism and its economic impact: a literature review using bibliometric tools, Tourism Econ., 25, pp. 109-131, (2019); Correia A.R., Wirasinghe S.C., de Barros A.G., Overall level of service measures for airport passenger terminals, Transport. Res. Part A Policy Pract., 42, pp. 330-346, (2008); Cronin J.J., Taylor S.A., Measuring service quality: a reexamination and extension, J. 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Air Transp. Manage.","Article","Final","","Scopus","2-s2.0-85135942713" -"Xu H.; Cheng X.; Wang T.; Wu S.; Xiong Y.","Xu, Hanqing (57697840900); Cheng, Xinyan (57962896400); Wang, Ting (57202606569); Wu, Shufen (57962719100); Xiong, Yongqi (57962198100)","57697840900; 57962896400; 57202606569; 57962719100; 57962198100","Mapping Neuroscience in the Field of Education through a Bibliometric Analysis","2022","Brain Sciences","12","11","1454","","","","7","10.3390/brainsci12111454","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141796457&doi=10.3390%2fbrainsci12111454&partnerID=40&md5=1fd36695a6e2b831bc32f6900a184f61","College of Science and Technology, Ningbo University, Cixi, 315211, China; Department of Sociology, McMaster University, Hamilton, L8S 4L8, ON, Canada; Ningbo Childhood Education College, Ningbo, 315336, China","Xu H., College of Science and Technology, Ningbo University, Cixi, 315211, China; Cheng X., Department of Sociology, McMaster University, Hamilton, L8S 4L8, ON, Canada; Wang T., College of Science and Technology, Ningbo University, Cixi, 315211, China; Wu S., Ningbo Childhood Education College, Ningbo, 315336, China; Xiong Y., College of Science and Technology, Ningbo University, Cixi, 315211, China","This study aimed to explore the core knowledge topics and future research trends in neuroscience in the field of education (NIE). In this study, we have explored the diffusion of neuroscience and different neuroscience methods (e.g., electroencephalography, functional magnetic resonance imaging, eye tracking) through and within education fields. A total of 549 existing scholarly articles and 25,886 references on neuroscience in the field of education (NIE) from the Web of Science Core Collection databases were examined during the following two periods: 1995–2013 and 2014–2022. The science mapping software Vosviewer and Bibliometrix were employed for data analysis and visualization of relevant literature. Furthermore, performance analysis, collaboration network analysis, co-citation network analysis, and strategic diagram analysis were conducted to systematically sort out the core knowledge in NIE. The results showed that children and cognitive neuroscience, students and medical education, emotion and empathy, and education and brain are the core intellectual themes of current research in NIE. Curriculum reform and children’s skill development have remained central research issues in NIE, and several topics on pediatric research are emerging. The core intellectual themes of NIE revealed in this study can help scholars to better understand NIE, save research time, and explore a new research question. To the best of our knowledge, this study is one of the earliest documents to outline the NIE core intellectual themes and identify the research opportunities emerging in the field. © 2022 by the authors.","bibliometric analysis; education; neuroscience; research topics; research trends","bibliometrics; brain; child; cognitive neuroscience; curriculum; diffusion; education; electroencephalography; emotion; empathy; eye tracking; female; functional magnetic resonance imaging; human; human experiment; male; medical education; network analysis; neuroscience; pediatrics; review; skill; software; Web of Science","","","","","Cixi Social Science Association, (2022SKY006); College of Science and Technology Ningbo University, (YK202216); Ningbo University, NBU","This research was funded by the College of Science and Technology Ningbo University (YK202216), Cixi Social Science Association (2022SKY006), and the K.C. 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Res, 50, pp. 649-656, (2021); Roberts M.E., Stewart B.M., Tingley D., stm: An R Package for Structural Topic Models, J. Stat. Softw, 91, pp. 1-40, (2019)","T. Wang; College of Science and Technology, Ningbo University, Cixi, 315211, China; email: wangting@nbu.edu.cn; S. Wu; Ningbo Childhood Education College, Ningbo, 315336, China; email: 2013017@ncec.edu.cn","","MDPI","","","","","","20763425","","","","English","Brain Sci.","Review","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85141796457" -"Xiao A.; Qin Y.; Xu Z.; Skare M.","Xiao, Anran (57211576389); Qin, Yong (57205945371); Xu, Zeshui (55502698400); Skare, Marinko (6506322858)","57211576389; 57205945371; 55502698400; 6506322858","A Comprehensive Bibliometric Analysis of Big Data in Entrepreneurship Research","2023","Engineering Economics","34","2","","175","192","17","6","10.5755/j01.ee.34.2.30643","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85164310703&doi=10.5755%2fj01.ee.34.2.30643&partnerID=40&md5=298f8465e4186e2ef292b806fc7f6114","Business School, Sichuan University, Chengdu, 610064, China; Juraj Dobrila Univ Pula, Fac Econ & Tourism Dr Mijo Mirkovic Preradoviceva 1-1, Pula, 52100, Croatia; University of Economics and Human Sciences, Warsaw, Poland","Xiao A., Business School, Sichuan University, Chengdu, 610064, China; Qin Y., Business School, Sichuan University, Chengdu, 610064, China; Xu Z., Business School, Sichuan University, Chengdu, 610064, China; Skare M., Juraj Dobrila Univ Pula, Fac Econ & Tourism Dr Mijo Mirkovic Preradoviceva 1-1, Pula, 52100, Croatia, University of Economics and Human Sciences, Warsaw, Poland","Big data technology has been widely used in entrepreneurial research in recent years. To explore the development trend and fundamental characteristics of big data in entrepreneurship (BDIE) research, we conduct a comprehensive bibliometric analysis of BDIE based on 541 publications between 1993 and 2020 from Web of Science. On the one hand, this paper focuses on some essential characteristics of the BDIE publications, such as categories, citation, H-index, and the most cited publications. On the other hand, visual scientific maps are presented by bibliometric tools, i.e., Bibliometrix, VOS viewer, and CorTexT Manager, showing relationships between publications and knowledge structure in BDIE research. Finally, hot topics in current studies, knowledge, and limitations are discussed, guiding scholars to explore new research directions. This paper provides a relatively broad perspective for applying BDIE research, which contributes to understanding the evolution of BDIE research and inspires scholars in related fields. © 2023, Kauno Technologijos Universitetas. All rights reserved.","Bibliometric Analysis; Big Data in Entrepreneurship; CorTexT Manager; Science Mapping","","","","","","National Natural Science Foundation of China, NSFC, (72071135); National Natural Science Foundation of China, NSFC; Ministry of Education of the People's Republic of China, MOE","Funding text 1: Zeshui Xu is currently a Professor with the Business School, Sichuan University, Chengdu. His current research interests include Decision-making theory and methodology, optimization algorithms, information fusion, and big data analytics. He was a Distinguished Young Scholar of the National Natural Science Foundation of China and the Chang Jiang Scholar of the Ministry of Education of China. He is currently the Senior Editor of IEEE Access, and the Associate Editor of IEEE Transactions on Cybernetics, IEEE Transactions on Fuzzy Systems, Information Sciences, Artificial Intelligence Review, Cognitive Computation, Applied Intelligence, Journal of the Operational Research, Fuzzy Optimization and Decision Making, etc.; Funding text 2: This study was funded by the National Natural Science Foundation of China (No. 72071135)","Akpor-Robaro Mamuzo, Oghen erobaro M., The impact of socio-cultural environment on entrepreneurial emergence: an empirical analysis of Nigeria society, Management Science & Engineering, 6, 4, pp. 82-92, (2012); Alsadi A. K., Alaskar T. H., Mezghani K., Adoption of big data analytics in supply chain management: Combining organizational factors with supply chain connectivity, International Journal of Information Systems and Supply Chain Management, 14, 2, pp. 88-107, (2021); Ambos T. 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X., A risk assessment algorithm for college student entrepreneurship based on big data analysis, Complexity, 2021, (2021); Zhou R., Ming L., Tao L., Characterizing the efficiency of data deduplication for big data storage management, Workload Characterization (IISWC), 2013 IEEE International Symposium on, pp. 98-108, (2014); Zulkefly N. A., Ghani N. A., Hamid S., Ahmad M., Gupta B. B., Harness the global impact of big data in nurturing social entrepreneurship: a systematic literature review, Journal of Global Information Management, 29, 6, (2021); Zurita R. T., Milian M. J. R., Diaz P. L., Digitization practices implemented in companies from human resources departments: critical analysis of the discourse, Prisma Social, 32, pp. 498-525, (2021)","Z. Xu; Business School, Sichuan University, Chengdu, 610064, China; email: xuzeshui@263.net","","Kauno Technologijos Universitetas","","","","","","13922785","","","","English","Eng. Econ.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85164310703" -"Peláez-Repiso A.; Sánchez-Núñez P.; García Calvente Y.","Peláez-Repiso, Andrea (57204710080); Sánchez-Núñez, Pablo (57204709743); García Calvente, Yolanda (57222654020)","57204710080; 57204709743; 57222654020","Tax regulation on blockchain and cryptocurrency: The implications for open innovation","2021","Journal of Open Innovation: Technology, Market, and Complexity","7","1","98","","","","17","10.3390/JOITMC7010098","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103639694&doi=10.3390%2fJOITMC7010098&partnerID=40&md5=68f83f451e7ca6cd6d29499d23a8beef","Department of Financial and Tax Law, Faculty of Law, Universidad de Málaga, Malaga, 29071, Spain; Center for Applied Social Research (CISA), Ada Byron Research Building, Universidad de Málaga, Malaga, 29071, Spain; Department of Audiovisual Communication and Advertising, Faculty of Communication Sciences, Universidad de Málaga, Malaga, 29071, Spain; Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, 29010, Spain","Peláez-Repiso A., Department of Financial and Tax Law, Faculty of Law, Universidad de Málaga, Malaga, 29071, Spain, Center for Applied Social Research (CISA), Ada Byron Research Building, Universidad de Málaga, Malaga, 29071, Spain; Sánchez-Núñez P., Center for Applied Social Research (CISA), Ada Byron Research Building, Universidad de Málaga, Malaga, 29071, Spain, Department of Audiovisual Communication and Advertising, Faculty of Communication Sciences, Universidad de Málaga, Malaga, 29071, Spain, Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, 29010, Spain; García Calvente Y., Department of Financial and Tax Law, Faculty of Law, Universidad de Málaga, Malaga, 29071, Spain","Blockchain is a technology that will change the relationships between the different actors in society, individuals, companies and administration, in aspects as important as taxation, by im-plementing concepts such as Self-sovereign identity (SSI) and Smart Contracts; which support, for example, virtual currencies, that are not controlled by any state, financial institution or centralized company. Hence, the growing interest of researchers, investors, traders, marketers, enterprises, and administrations to know the scope of this new technology and its tax implications. The main objective of this work is to clarify the status of these studies, explore issues, methods, findings, and trends as well as to define their meaning within the current research scenario. To achieve these objectives, bibliometric analysis was carried out, retrieving 349 research papers, and analyzing 343 papers published between 2015–2019 based on the results of the Web of Science (WoS). © 2021 by the authors. Licensee MDPI, Basel, Switzerland.","Bibliometrix; E-commerce; Financial law; Financial markets; Informetrics; Legal; Science mapping analysis; Scientometrics; Virtual currencies; Virtual money","","","","","","","","Lewis R., McPartland J., Ranjan R., Lewis R., McPartland J., Blockchain and Financial Market Innovation, Econ. Perspect, 7, pp. 2-12, (2017); Bohme R., Christin N., Edelman B., Moore T., Bitcoin: Economics, Technology, and Governance, J. Econ. Perspect, 29, pp. 213-238, (2015); Savelyev A., Legal aspects of ownership in modified open source software and its impact on Russian software import substitution policy, Comput. Law Secur. Rev, 33, pp. 193-210, (2017); Gai K., Qiu M., Sun X., A survey on FinTech, J. Netw. Comput. Appl, 103, pp. 262-273, (2018); Huckle S., Bhattacharya R., White M., Beloff N., Internet of Things, Blockchain and Shared Economy Applications, Procedia Comput. Sci, 98, pp. 461-466, (2016); Christidis K., Devetsikiotis M., Blockchains and Smart Contracts for the Internet of Things, IEEE Access, 4, pp. 2292-2303, (2016); Liu Y., He D., Obaidat M.S., Kumar N., Khan M.K., Raymond Choo K.-K., Blockchain-based identity management systems: A review, J. Netw. Comput. Appl, 166, (2020); Nofer M., Gomber P., Hinz O., Schiereck D., Blockchain, Bus. Inf. Syst. Eng, 59, pp. 183-187, (2017); Sullivan C., Burger E., E-residency and blockchain, Comput. Law Secur. Rev, 33, pp. 470-481, (2017); Chan S., Chu J., Zhang Y., Nadarajah S., Blockchain and Cryptocurrencies, J. Risk Financ. Manag, 13, (2020); Legeren-Molina A., Los contratos inteligentes en España. La disciplina de los Smart Contracts, Rev. Derecho Civ, 5, pp. 193-241, (2018); Mikhaylov A., Cryptocurrency Market Analysis from the Open Innovation Perspective, J. Open Innov. Technol. Mark. Complex, 6, (2020); Wang S., Ouyang L., Yuan Y., Ni X., Han X., Wang F.-Y.Y., Blockchain-Enabled Smart Contracts: Architecture, Applications, and Future Trends, IEEE Trans. Syst. Man Cybern. Syst, 49, pp. 2266-2277, (2019); Kshetri N., Blockchain’s roles in strengthening cybersecurity and protecting privacy, Telecomm. Policy, 41, pp. 1027-1038, (2017); Boucher P., Nascimento S., Kritikos M., How Blockchain Technology Could Change Our Lives, Eur. 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Lett, (2020); Miau S., Yang J.-M., Bibliometrics-based evaluation of the Blockchain research trend: 2008–March 2017, Technol. Anal. Strateg. Manag, 30, pp. 1029-1045, (2018); Sanchez-Nunez P., Cobo M.J., Las Heras-Pedrosa C.D., Pelaez J.I., Herrera-Viedma E., de las Heras-Pedrosa C., Pelaez J.I., Herrera-Viedma E., Opinion Mining, Sentiment Analysis and Emotion Understanding in Advertising: A Bibliometric Analysis, IEEE Access, 8, pp. 134563-134576, (2020); Montero Diaz J., Cobo M., Gutierrez M., Segado Boj F., Herrera Viedma E., Mapeo científico de la Categoría «Comunicación» en WoS (1980-2013), Comun. Rev. Científica Iberoam. Comun. y Educ, pp. 81-91, (2018); Perez-Cabezas V., Ruiz-Molinero C., Carmona-Barrientos I., Herrera-Viedma E., Cobo M.J., Moral-Munoz J.A., Highly cited papers in rheumatology: Identification and conceptual analysis, Scientometrics, 116, pp. 555-568, (2018); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr, 11, pp. 959-975, (2017); Pelaez-Repiso A., Sanchez-Nunez P., Calvente Y.G., Tax Regulation on Blockchain and Cryptocurrency: The Implications for Open Innovation (Citation Report and WoS Dataset), Zenodo, (2021); Aria M., Misuraca M., Spano M., Mapping the Evolution of Social Research and Data Science on 30 Years of Social Indicators Research, Soc. Indic. 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Horiz, 61, pp. 567-575, (2018); Yun J.J., Won D., Park K., Entrepreneurial cyclical dynamics of open innovation, J. Evol. Econ, 28, pp. 1151-1174, (2018); Yun J.J., Liu Z., Micro-and Macro-Dynamics of Open Innovation with a Quadruple-Helix Model, Sustainability, 11, (2019); Maicher L., Gibovic D., de la Rosa J.L., Torres-Padrosa V., On Intellectual Property in Online Open Innovation for SME by means of Blockchain and Smart Contracts, Proceedings of the World Open Innovation Conference 2016 (WOIC2016), (2016); Torres-salinas D., Group S.C., Researcher C., Jim E., Altmetrics: New indicators for scientific communication in Web 2.0, Comunicar, 2013, pp. 1-9, (2015)","P. Sánchez-Núñez; Center for Applied Social Research (CISA), Ada Byron Research Building, Universidad de Málaga, Malaga, 29071, Spain; email: psancheznunez@uma.es; P. Sánchez-Núñez; Department of Audiovisual Communication and Advertising, Faculty of Communication Sciences, Universidad de Málaga, Malaga, 29071, Spain; email: psancheznunez@uma.es; P. Sánchez-Núñez; Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, 29010, Spain; email: psancheznunez@uma.es","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","21998531","","","","English","J. Open Innov.: Technol. Mark. Complex.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85103639694" -"Lizano-Mora H.; Palos-Sanchez P.R.; Aguayo-Camacho M.","Lizano-Mora, Henry (57222548433); Palos-Sanchez, Pedro R. (57193833640); Aguayo-Camacho, Mariano (57193831139)","57222548433; 57193833640; 57193831139","The evolution of business process management: A bibliometric analysis","2021","IEEE Access","9","","9380411","51088","51105","17","31","10.1109/ACCESS.2021.3066340","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103151266&doi=10.1109%2fACCESS.2021.3066340&partnerID=40&md5=1c33c408adbab0bc0582c2eecab4f675","School of Business Administration, Technological Institute of Costa Rica, Cartago, 30101, Costa Rica; Department of Financial Economy and Operation Research, University of Seville, Seville, 41018, Spain","Lizano-Mora H., School of Business Administration, Technological Institute of Costa Rica, Cartago, 30101, Costa Rica; Palos-Sanchez P.R., Department of Financial Economy and Operation Research, University of Seville, Seville, 41018, Spain; Aguayo-Camacho M., Department of Financial Economy and Operation Research, University of Seville, Seville, 41018, Spain","This paper will present the research results for the analysis of the presence and evolution of the term Business Process Management (BPM) in the period 2000-2020 using a literature review with bibliometric analysis. This research sought to evaluate the quantity and quality of empirical support for the use of this tool in organizations. This allowed the researchers to acknowledge and confirm this discipline as an important investigation domain with great potential for helping companies achieve strategic alignment between business and information and communication technologies in the future. The Science Mapping Workflow methodology was used with database and search criteria applied to a total of 1,706 articles related to the subject, which resulted in a total of 624 articles selected for further research. This study identifies the journals that have the most publications about BPM. It concludes that the most promising perspectives are the ones related to Management, Framework and Performance. Even though, from a conceptual viewpoint, performance is the most valued perspective. Lastly, this research is of great interest for academics and professionals who hope to strengthen their knowledge about the BPM concept and find the historical path and the main authors and issues that contribute to knowledge in this scientific field. © 2013 IEEE.","bibliometrix; Business process management; business process reengineering; customer relationship management; enterprise resource planning; science mapping workflow","Enterprise resource management; Bibliometric analysis; Business process management; Information and Communication Technologies; Literature reviews; Research results; Scientific fields; Search criterion; Strategic alignment; Quality control","","","","","","","Harmon P., Business Process Change: A Business Process Management Guide for Managers and Process Professionals, (2019); Smith H., Fingar P., Business Process Management: The Third Wave, 1, (2003); Taandlor F.W., The Principles of Scientific Management, (1914); Davenport T.H., Process Innovation: Reengineering Work through Infor-mation Technologand, (1993); Jeston J., Business Process Management: Practical Guidelines to Success-ful Implementations, 4th Ed., (2018); Ongena G., Ravesteyn P., Business process management maturity and performance: A multi group analysis of sectors and organization sizes, Bus. Process Manage. J., 26, 1, pp. 132-149, (2019); Vugec D.S., Ivancic L., Glavan L.M., Business process management and corporate performance management: Does their alignment impact organizational performance, Interdiscipl. Description Complex Syst., 17, 2, pp. 368-384, (2019); Ubaid A.M., Dweiri F.T., Business process management (BPM): Terminologies and methodologies unified, Int. J. Syst. Assurance Eng. Manage., 11, pp. 1046-1064, (2020); Benedict T., Bpm CBOK: Business Process Management Common Body of Knowledge (BPM Cbok R), (2013); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, J. Amer. Soc. For Inf. Sci. Technol., 62, 7, pp. 1382-1402, (2011); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. 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W.M., Pesic M., Schonenberg H., Declarative workflows: Balancing between flexibility and support, Comput. Sci.-Res. Develop., 23, 2, pp. 99-113, (2009); Aalst Der Van P. W.M., Schonenberg M.H., Song M., Time prediction based on process mining, Inf. Syst., 36, 2, pp. 450-475, (2011); Aalst V.D., Ter Hofstede A.H.M., Weske M., Business Process Management: A Survey, 2678, (2003); Hammer M., Champand J., Reengineering the corporation: A manifesto for business revolution, Business Horizons, 36, 5, pp. 90-91, (1993); Aalst Der Van P. W.M., The application of Petri nets to workflow management, J. Circuits, Syst. Comput., 8, 1, pp. 21-66, (1998); Kohlbacher M., The effects of process orientation: A literature review, Bus. Process Manage. 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Sci., 44, (1993); Gabryelczyk R., Roztocki N., Effects of Bpm on Erp Adoption in the Public Sector, (2017); Wen Y., Yuan H., Zhang P., Research on keyword extraction based on Word2 Vec weighted TextRank, In Proc. 2nd Ieee Int. Conf. Com-put. Commun. (ICCC), pp. 2109-2113, (2016); Lahajnar S., Roanec A., The evaluation framework for business process management methodologies, Manag. J. Contemp. Manag., 21, 1, pp. 47-69, (2016); Leite J.C.S.D.P., Santoro F.M., Cappelli C., Batista T.V., Santos F.J.N., Ownership relevance in aspect-oriented business process models, Bus. Process Manage. J., 22, 3, pp. 566-593, (2016); Osterwalder A., Pigneur A., Designing business models and similar strategic objects: The contribution of IS, J. Assoc. Inf. Sandst., 14, 5, (2013); Small H., Update on science mapping: Creating large document spaces, Scientometrics, 38, 2, pp. 275-293, (1997); Blondel V., Guillaume J.L., Lambiotte R., Lefebvre E., Fast unfolding of communities in large networks, J. Stat. Mech. Theo-rand Express, 2008, 10, pp. 1-12, (2008); Abdi H., Dominique V., Multiple correspondence analysis, Metr. Scaling, 2, pp. 86-91, (2012); Salkind N., Oaks C.A.T., Agresti A.S., Encandclopedia of measurement and statistics, Stat. Sci, 7, pp. 131-153, (2007); Podani J., Denes S., On dendrogram-based measures of functional diversity, Oikos, 115, 1, pp. 179-185, (2006); Cuccurullo C., Aria M., Sarto F., Foundations and trends in performance management. A twenty-five years bibliometric analysis in business and public administration domains, Scientometrics, 108, 2, pp. 595-611, (2016); Akanduz A.G., Erkan E., Suppland chain performance measurement: A literature review, Int. J. Prod. Res., 48, 17, pp. 5137-5155, (2010); Small H., Co-citation in the scientific literature: A new measure of the relationship between two documents, J. Amer. Soc. Inf. Sci., 24, 4, pp. 265-269, (1973); Garfield E., Historiographic mapping of knowledge domains literature, J. Inf. Sci., 30, 2, pp. 119-145, (2004); Peters H.P.F., Van Raan A.F.J., Structuring scientific activities by co-author analysis: An expercise on a university faculty level, Scientometrics, 20, 1, pp. 235-255, (1991); Recker J., Mendling J., The state-of-the-art of business process management research as published in the bpm conference: Recommendations for progressing the field, In Proc. Bpm Conf. Bus. Inf. Syst. Eng., 58, pp. 55-72, (2016); Danilova K.B., Process owners in business process management: A systematic literature review, Bus. Process Manage. J., 25, 6, pp. 1377-1412, (2019); Palos P.R., Correia M.B., La actitud de los recursos humanos de las organizaciones ante la complejidad de las aplicaciones SaaS, Dos Algarves, Multidisciplinary E-J., 28, pp. 87-103, (2016)","P.R. Palos-Sanchez; Department of Financial Economy and Operation Research, University of Seville, Seville, 41018, Spain; email: ppalos@us.es","","Institute of Electrical and Electronics Engineers Inc.","","","","","","21693536","","","","English","IEEE Access","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85103151266" -"Li J.; Cossette-Roberge H.; Toffa D.H.; Deacon C.; Keezer M.R.","Li, Jimmy (57226699683); Cossette-Roberge, Hélène (57224056072); Toffa, Dènahin Hinnoutondji (56061863900); Deacon, Charles (14007908600); Keezer, Mark Robert (18437280500)","57226699683; 57224056072; 56061863900; 14007908600; 18437280500","Sudden unexpected death in epilepsy (SUDEP): A bibliometric analysis","2023","Epilepsy Research","193","","107159","","","","2","10.1016/j.eplepsyres.2023.107159","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85158858601&doi=10.1016%2fj.eplepsyres.2023.107159&partnerID=40&md5=2615899eccb7ebb29332e6f921d71f09","Neurology Division, Centre Hospitalier de l'Université de Sherbrooke (CHUS), Sherbrooke, QC, Canada; Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada; Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada; Department of Neurosciences, Université de Montréal, Montreal, QC, Canada; School of Public Health, Université de Montréal, Montreal, QC, Canada; Neurology Division, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada","Li J., Neurology Division, Centre Hospitalier de l'Université de Sherbrooke (CHUS), Sherbrooke, QC, Canada, Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada; Cossette-Roberge H., Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada; Toffa D.H., Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada, Department of Neurosciences, Université de Montréal, Montreal, QC, Canada; Deacon C., Neurology Division, Centre Hospitalier de l'Université de Sherbrooke (CHUS), Sherbrooke, QC, Canada; Keezer M.R., Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada, Department of Neurosciences, Université de Montréal, Montreal, QC, Canada, School of Public Health, Université de Montréal, Montreal, QC, Canada, Neurology Division, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada","Objective: The literature on sudden unexpected death in epilepsy (SUDEP) has been evolving at a staggering rate. We conducted a bibliometric analysis of the SUDEP literature with the aim of presenting its structure, performance, and trends. Methods: The Scopus database was searched in April 2023 for documents explicitly detailing SUDEP in their title, abstract, or keywords. After the removal of duplicate documents, bibliometric analysis was performed using the R package bibliometrix and the program VOSviewer. Performance metrics were computed to describe the literature's annual productivity, most relevant authors and countries, and most important publications. Science mapping was performed to visualize the relationships between research constituents by constructing a country collaboration network, co-authorship network, keyword co-occurrence network, and document co-citation network. Results: A total of 2140 documents were analyzed. These documents were published from 1989 onward, with an average number of citations per document of 25.78. Annual productivity had been on the rise since 2006. Out of 6502 authors, five authors were in both the list of the ten most productive and the list of the ten most cited authors: Devinsky O, Sander JW, Tomson T, Ryvlin P, and Lhatoo SD. The USA and the United Kingdom were the most productive and cited countries. Collaborations between American authors and European authors were particularly rich. Prominent themes in the literature included those related to pathophysiology (e.g., cardiac arrhythmia, apnea, autonomic dysfunction), epilepsy characteristics (e.g., epilepsy type, refractoriness, antiseizure medications), and epidemiology (e.g., incidence, age, sex). Emerging themes included sleep, genetics, epilepsy refractoriness, and non-human studies. Significance: The body of literature on SUDEP is rich, fast-growing, and benefiting from frequent international collaborations. Some research themes such as sleep, genetics, and animal studies have become more prevalent over recent years. © 2023 Elsevier B.V.","Bibliometric; Epilepsy; Review; Sudden death; SUDEP","Animals; Bibliometrics; Death, Sudden; Epilepsy; Sleep; Sudden Unexpected Death in Epilepsy; carbamazepine; lamotrigine; phenytoin; apnea; Article; genetic counseling; heart arrhythmia; human; performance indicator; prevalence; sleep; sudden unexpected death in epilepsy; tonic clonic seizure; animal; bibliometrics; complication; epilepsy; etiology; physiology; sudden death","","carbamazepine, 298-46-4, 8047-84-5; lamotrigine, 84057-84-1; phenytoin, 57-41-0, 630-93-3","","","","","Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr., 11, pp. 959-975, (2017); Aurlien D., Gjerstad L., Tauboll E., The role of antiepileptic drugs in sudden unexpected death in epilepsy, Seizure, 43, pp. 56-60, (2016); Bateman L.M., Li C.S., Seyal M., Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors, Brain, 131, pp. 3239-3245, (2008); Bateman L.M., Spitz M., Seyal M., Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: report on two deaths in video-EEG-monitored patients, Epilepsia, 51, pp. 916-920, (2010); Dasheiff R.M., Sudden unexpected death in epilepsy: a series from an epilepsy surgery program and speculation on the relationship to sudden cardiac death, J. Clin. Neurophysiol., 8, pp. 216-222, (1991); Devinsky O., Sudden, unexpected death in epilepsy, N. Engl. J. Med, 365, pp. 1801-1811, (2011); Devinsky O., Hesdorffer D.C., Thurman D.J., Et al., Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention, Lancet Neurol., 15, pp. 1075-1088, (2016); Donthu N., Kumar S., Mukherjee D., Et al., How to conduct a bibliometric analysis: An overview and guidelines, J. Bus. Res., 133, pp. 285-296, (2021); Duncan J.S., Sander J.W., Sisodiya S.M., Et al., Adult epilepsy, Lancet, 367, pp. 1087-1100, (2006); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, pp. 523-538, (2010); Einarsdottir A.B., Sveinsson O., Olafsson E., Sudden unexpected death in epilepsy. A nationwide population-based study, Epilepsia, 60, pp. 2174-2181, (2019); Falagas M.E., Pitsouni E.I., Malietzis G.A., Et al., Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses, FASEB J., 22, pp. 338-342, (2008); Ficker D.M., So E.L., Shen W.K., Et al., Population-based study of the incidence of sudden unexplained death in epilepsy, Neurology, 51, pp. 1270-1274, (1998); Fiest K.M., Sauro K.M., Wiebe S., Et al., Prevalence and incidence of epilepsy: A systematic review and meta-analysis of international studies, Neurology, 88, pp. 296-303, (2017); Harden C., Tomson T., Gloss D., Et al., Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and risk factors: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society, Neurology, 88, pp. 1674-1680, (2017); Hesdorffer D.C., Tomson T., Benn E., Et al., Combined analysis of risk factors for SUDEP, Epilepsia, 52, pp. 1150-1159, (2011); Hesdorffer D.C., Tomson T., Benn E., Et al., Do antiepileptic drugs or generalized tonic-clonic seizure frequency increase SUDEP risk? A combined analysis, Epilepsia, 53, pp. 249-252, (2012); Kloster R., Engelskjon T., Sudden unexpected death in epilepsy (SUDEP): a clinical perspective and a search for risk factors, J. Neurol. Neurosurg. Psychiatry, 67, pp. 439-444, (1999); Klovgaard M., Lynge T.H., Tsiropoulos I., Et al., Sudden unexpected death in epilepsy in persons younger than 50 years: A retrospective nationwide cohort study in Denmark, Epilepsia, 62, pp. 2405-2415, (2021); Klovgaard M., Sabers A., Ryvlin P., Update on Sudden Unexpected Death in Epilepsy, Neurol. Clin., 40, pp. 741-754, (2022); Lamberts R.J., Thijs R.D., Laffan A., Et al., Sudden unexpected death in epilepsy: people with nocturnal seizures may be at highest risk, Epilepsia, 53, pp. 253-257, (2012); Langan Y., Nashef L., Sander J.W., Sudden unexpected death in epilepsy: a series of witnessed deaths, J. Neurol. Neurosurg. Psychiatry, 68, pp. 211-213, (2000); Langan Y., Nashef L., Sander J.W., Case-control study of SUDEP, Neurology, 64, pp. 1131-1133, (2005); Leestma J.E., Walczak T., Hughes J.R., Et al., A prospective study on sudden unexpected death in epilepsy, Ann. Neurol., 26, pp. 195-203, (1989); Leestma J.E., Annegers J.F., Brodie M.J., Et al., Sudden unexplained death in epilepsy: observations from a large clinical development program, Epilepsia, 38, pp. 47-55, (1997); Lhatoo S.D., Faulkner H.J., Dembny K., Et al., An electroclinical case-control study of sudden unexpected death in epilepsy, Ann. Neurol., 68, pp. 787-796, (2010); Massey C.A., Sowers L.P., Dlouhy B.J., Et al., Mechanisms of sudden unexpected death in epilepsy: the pathway to prevention, Nat. Rev. Neurol., 10, pp. 271-282, (2014); Nashef L., Sudden unexpected death in epilepsy: terminology and definitions, Epilepsia, 38, pp. S6-S8, (1997); Nashef L., Walker F., Allen P., Et al., Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy, J. Neurol. Neurosurg. Psychiatry, 60, pp. 297-300, (1996); Nashef L., So E.L., Ryvlin P., Et al., Unifying the definitions of sudden unexpected death in epilepsy, Epilepsia, 53, pp. 227-233, (2012); Natelson B.H., Suarez R.V., Terrence C.F., Et al., Patients with epilepsy who die suddenly have cardiac disease, Arch. Neurol., 55, pp. 857-860, (1998); Nei M., Ho R.T., Sperling M.R., EKG abnormalities during partial seizures in refractory epilepsy, Epilepsia, 41, pp. 542-548, (2000); Nilsson L., Farahmand B.Y., Persson P.G., Et al., Risk factors for sudden unexpected death in epilepsy: a case-control study, Lancet, 353, pp. 888-893, (1999); Opeskin K., Berkovic S.F., Risk factors for sudden unexpected death in epilepsy: a controlled prospective study based on coroners cases, Seizure, 12, pp. 456-464, (2003); Opherk C., Coromilas J., Hirsch L.J., Heart rate and EKG changes in 102 seizures: analysis of influencing factors, Epilepsy Res, 52, pp. 117-127, (2002); (2021); Rocamora R., Kurthen M., Lickfett L., Et al., Cardiac asystole in epilepsy: clinical and neurophysiologic features, Epilepsia, 44, pp. 179-185, (2003); Rugg-Gunn F.J., Simister R.J., Squirrell M., Et al., Cardiac arrhythmias in focal epilepsy: a prospective long-term study, Lancet, 364, pp. 2212-2219, (2004); Ryvlin P., Cucherat M., Rheims S., Risk of sudden unexpected death in epilepsy in patients given adjunctive antiepileptic treatment for refractory seizures: a meta-analysis of placebo-controlled randomised trials, Lancet Neurol., 10, pp. 961-968, (2011); Ryvlin P., Nashef L., Lhatoo S.D., Et al., Incidence and mechanisms of cardiorespiratory arrests in epilepsy monitoring units (MORTEMUS): a retrospective study, Lancet Neurol., 12, pp. 966-977, (2013); Shorvon S., Tomson T., Sudden unexpected death in epilepsy, Lancet, 378, pp. 2028-2038, (2011); Sillanpaa M., Shinnar S., Long-term mortality in childhood-onset epilepsy, N. Engl. J. Med, 363, pp. 2522-2529, (2010); Singh V.K., Singh P., Karmakar M., Et al., The journal coverage of Web of Science, Scopus and Dimensions: A comparative analysis, Scientometrics, 126, pp. 5113-5142, (2021); So E.L., Sam M.C., Lagerlund T.L., Postictal central apnea as a cause of SUDEP: evidence from near-SUDEP incident, Epilepsia, 41, pp. 1494-1497, (2000); Stollberger C., Finsterer J., Cardiorespiratory findings in sudden unexplained/unexpected death in epilepsy (SUDEP), Epilepsy Res, 59, pp. 51-60, (2004); Surges R., Thijs R.D., Tan H.L., Et al., Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms, Nat. Rev. Neurol., 5, pp. 492-504, (2009); Surges R., Scott C.A., Walker M.C., Enhanced QT shortening and persistent tachycardia after generalized seizures, Neurology, 74, pp. 421-426, (2010); Sveinsson O., Andersson T., Carlsson S., Et al., The incidence of SUDEP: A nationwide population-based cohort study, Neurology, 89, pp. 170-177, (2017); Sveinsson O., Andersson T., Mattsson P., Et al., Clinical risk factors in SUDEP: A nationwide population-based case-control study, Neurology, 94, pp. e419-e429, (2020); Tellez-Zenteno J.F., Ronquillo L.H., Wiebe S., Sudden unexpected death in epilepsy: evidence-based analysis of incidence and risk factors, Epilepsy Res, 65, pp. 101-115, (2005); Tennis P., Cole T.B., Annegers J.F., Et al., Cohort study of incidence of sudden unexplained death in persons with seizure disorder treated with antiepileptic drugs in Saskatchewan, Canada, Epilepsia, 36, pp. 29-36, (1995); Thijs R.D., Ryvlin P., Surges R., Autonomic manifestations of epilepsy: emerging pathways to sudden death?, Nat. Rev. Neurol., 17, pp. 774-788, (2021); Thurman D.J., Hesdorffer D.C., French J.A., Sudden unexpected death in epilepsy: assessing the public health burden, Epilepsia, 55, pp. 1479-1485, (2014); Timmings P.L., Sudden unexpected death in epilepsy: a local audit, Seizure, 2, pp. 287-290, (1993); Tomson T., Walczak T., Sillanpaa M., Et al., Sudden unexpected death in epilepsy: a review of incidence and risk factors, Epilepsia, 46, pp. 54-61, (2005); Tomson T., Nashef L., Ryvlin P., Sudden unexpected death in epilepsy: current knowledge and future directions, Lancet Neurol., 7, pp. 1021-1031, (2008); Tupal S., Faingold C.L., Evidence supporting a role of serotonin in modulation of sudden death induced by seizures in DBA/2 mice, Epilepsia, 47, pp. 21-26, (2006); Venit E.L., Shepard B.D., Seyfried T.N., Oxygenation prevents sudden death in seizure-prone mice, Epilepsia, 45, pp. 993-996, (2004); Verducci C., Friedman D., Donner E., Et al., Genetic generalized and focal epilepsy prevalence in the North American SUDEP Registry, Neurology, 94, pp. e1757-e1763, (2020); Walczak T.S., Leppik I.E., D'Amelio M., Et al., Incidence and risk factors in sudden unexpected death in epilepsy: a prospective cohort study, Neurology, 56, pp. 519-525, (2001)","M.R. Keezer; Centre Hospitalier de l'Université de Montréal, Montréal, 1000 rue Saint-Denis, H2X 0C1, Canada; email: mark.keezer@umontreal.ca","","Elsevier B.V.","","","","","","09201211","","EPIRE","37167883","English","Epilepsy Res.","Article","Final","","Scopus","2-s2.0-85158858601" -"Elomari Y.; Norouzi M.; Marín-Genescà M.; Fernández A.; Boer D.","Elomari, Youssef (57872871100); Norouzi, Masoud (57223850337); Marín-Genescà, Marc (38661445400); Fernández, Alberto (56016225400); Boer, Dieter (7003615369)","57872871100; 57223850337; 38661445400; 56016225400; 7003615369","Integration of Solar Photovoltaic Systems into Power Networks: A Scientific Evolution Analysis","2022","Sustainability (Switzerland)","14","15","9249","","","","23","10.3390/su14159249","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137175280&doi=10.3390%2fsu14159249&partnerID=40&md5=a95966de3427160e6fd91acb0be77523","Departament d’Enginyeria Mecànica, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain; Departament d’Enginyeria Química, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain","Elomari Y., Departament d’Enginyeria Mecànica, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain; Norouzi M., Departament d’Enginyeria Química, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain; Marín-Genescà M., Departament d’Enginyeria Mecànica, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain; Fernández A., Departament d’Enginyeria Química, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain; Boer D., Departament d’Enginyeria Mecànica, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain","Solar photovoltaic (PV) systems have drawn significant attention over the last decade. One of the most critical obstacles that must be overcome is distributed energy generation. This paper presents a comprehensive quantitative bibliometric study to identify the new trends and call attention to the evolution within the research landscape concerning the integration of solar PV in power networks. The research is based on 7146 documents that were authored between 2000–2021 and downloaded from the Web of Science database. Using an in-house bibliometric tool, Bibliometrix R-package, and the open-source tool VOSviewer we obtained bibliometric indicators, mapped the network analysis, and performed a multivariate statistical analysis. The works that were based on solar photovoltaics into power networks presented rapid growth, especially in India. The co-occurrence analysis showed that the five main clusters, classified according to dimensions and significance, are (i) power quality issues that are caused by the solar photovoltaic penetration in power networks; (ii) algorithms for energy storage, demand response, and energy management in the smart grid; (iii) optimization, techno-economic analysis, sensitivity analysis, and energy cost analysis for an optimal hybrid power system; (iv) renewable energy integration, self-consumption, energy efficiency, and sustainable development; and (v) modeling, simulation, and control of battery energy storage systems. The results revealed that researchers pay close attention to “renewable energy”, “microgrid”, “energy storage”, “optimization”, and “smart grid”, as the top five keywords in the past four years. The results also suggested that (i) power quality; (ii) voltage and frequency fluctuation problems; (iii) optimal design and energy management; and (iv) technical-economic analysis, are the most recent investigative foci that might be appraised as having the most budding research prospects. © 2022 by the authors.","bibliometric analysis; power networks; renewable energy; science mapping; solar photovoltaic (PV)","India; alternative energy; bibliography; cost analysis; energy management; energy storage; mapping method; photovoltaic system; solar power","","","","","Tarragona’s council, (2021PGR-DIPTA-URV01); Ministerio de Ciencia, Innovación y Universidades, MCIU; Generalitat de Catalunya, (2017-SGR-1409); Generalitat de Catalunya; Ministerio de Economía y Competitividad, MINECO, (RTI2018-093849-B-C33); Ministerio de Economía y Competitividad, MINECO; Agencia Estatal de Investigación, AEI, (RED2018-102431-T); Agencia Estatal de Investigación, AEI","The authors would like to acknowledge financial support from the Spanish Ministry of Economy and Competitiveness RTI2018-093849-B-C33 (MCIU/AEI/FEDER, UE), the Catalan Government (2017-SGR-1409), and the Tarragona’s council (2021PGR-DIPTA-URV01). This work is partially funded by the Ministerio de Ciencia, Innovación y Universidades—Agencia Estatal de Investigación (AEI) (RED2018-102431-T). ","Obeidat F., A Comprehensive Review of Future Photovoltaic Systems, Sol. Energy, 163, pp. 545-551, (2018); Criqui P., Mima S., European Climate-Energy Security Nexus: A Model Based Scenario Analysis, Energy Policy, 41, pp. 827-842, (2012); Al-Shetwi A.Q., Sujod M.Z., Grid-Connected Photovoltaic Power Plants: A Review of the Recent Integration Requirements in Modern Grid Codes, Int. J. Energy Res, 42, pp. 1849-1865, (2018); Kabir E., Kumar P., Kumar S., Adelodun A.A., Kim K.H., Solar Energy: Potential and Future Prospects, Renew. Sustain. Energy Rev, 82, pp. 894-900, (2018); Kent R., Renewables, Plast. Eng, 74, pp. 56-57, (2018); Renewable Power Generation Costs in 2019, (2020); Yang Y., Zhou K., Blaabjerg F., Current Harmonics from Single-Phase Grid-Connected Inverters-Examination and Suppression, IEEE J. Emerg. Sel. Top. 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Paisos Catalans 26, 43007, Spain; email: dieter.boer@urv.cat","","MDPI","","","","","","20711050","","","","English","Sustainability","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85137175280" -"Schirone M.","Schirone, Marco (57221220992)","57221220992","STEM Information Literacy: A Bibliometric Mapping (1974-2020)","2022","Communications in Computer and Information Science","1533 CCIS","","","385","395","10","2","10.1007/978-3-030-99885-1_33","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128781736&doi=10.1007%2f978-3-030-99885-1_33&partnerID=40&md5=ed3f5b4098698912dd59a266f1125fc3","Chalmers University of Technology, Göteborg, Sweden; University of Borås, Borås, Sweden","Schirone M., Chalmers University of Technology, Göteborg, Sweden, University of Borås, Borås, Sweden","This exploratory paper investigates with bibliometric methods the area of research and practice constituted by information literacy in science, technology, engineering, and mathematics (STEM). Amongst the findings are the most central publication channels, authors, and topics. Academic librarianship and library and information science appear as intellectual bases for this field, although a degree of specialisation (particularly towards the health sciences and engineering) also emerges. The findings are discussed in light of Richard Whitley’s sociology of science and Annemaree Lloyd’s sociocultural approach to information literacy. © 2022, Springer Nature Switzerland AG.","Bibliometric mapping; Bibliometrics; Bibliometrix; Information literacy; Science mapping; Sociology of science; STEM; STEM information literacy","Engineering education; Bibliometric; Bibliometric mapping; Bibliometrix; Engineering and mathematics; Information literacy; Science mapping; Science technologies; Science, technology, engineering, and mathematic; Science, technology, engineering, and mathematic information literacy; Sociology of science; Mapping","","","","","","","Harris S.Y., Undergraduates’ assessment of science, technology, engineering and mathematics (STEM) information literacy instruction, IFLA J, 43, pp. 171-186, (2017); Bybee R.W., What is STEM education?, Science, 329, (2010); Phillips M., van Epps A., Johnson N., Zwicky D., Effective engineering information literacy instruction: A systematic literature review, J. Acad. Librariansh., 44, pp. 705-711, (2018); Bawden D., Robinson L., ‘An intensity around information’: The changing face of chemical information literacy, J. Inf. Sci., 43, pp. 17-24, (2017); Kates R.W., Et al., Sustainability science, Science, 292, pp. 641-642, (2001); Information Literacy: Moving Toward Sustainability. Third European Conference, ECIL 2015 Tallinn, Estonia, October 19–22, 2015, (2015); Pinto M., Fernandez-Pascual R., Caballero-Mariscal D., Sales D., Information literacy trends in higher education (2006–2019): Visualizing the emerging field of mobile information literacy, Scientometrics, 124, 2, pp. 1479-1510, (2020); Stopar K., Bartol T., Digital competencies, computer skills and information literacy in secondary education: Mapping and visualization of trends and concepts, Scientometrics, 118, pp. 479-498, (2019); Kaufman J., Tenopir C., Christian L., Does workplace matter? 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Libr., 65, pp. 96-121, (2004); Callon M., Courtial J.P., Laville F., Co-word analysis as a tool for describing the network of interactions between basic and technological research: The case of polymer chemistry, Scientometrics, 22, pp. 155-205, (1991); Leydesdorff L., The Evolutionary Dynamics of Discursive Knowledge: Communication-Theoretical Perspectives on an Empirical Philosophy of Science, (2021); Whitley R., The Intellectual and Social Organization of the Sciences, (2000); Lloyd A., Recasting information literacy as sociocultural practice: implications for library and information science researchers, Inf. Res., 12, (2007); Phillips M.E., Fosmire M., Schirone M., Johansson C., Berry F., Workplace information needs of engineering and technology graduates: A case study on two continents, IEEE Frontiers in Education Conference (FIE), pp. 1-5, (2020)","M. Schirone; Chalmers University of Technology, Göteborg, Sweden; email: marco.schirone@chalmers.se","Kurbanoğlu S.; Špiranec S.; Ünal Y.; Boustany J.; Kos D.","Springer Science and Business Media Deutschland GmbH","","7th European Conference on Information Literacy, ECIL 2021","20 September 2021 through 23 September 2021","Virtual, Online","276479","18650929","978-303099884-4","","","English","Commun. Comput. Info. Sci.","Conference paper","Final","","Scopus","2-s2.0-85128781736" -"Yalcinkaya T.; Cinar Yucel S.","Yalcinkaya, Turgay (57976961500); Cinar Yucel, Sebnem (51161095400)","57976961500; 51161095400","Mobile learning in nursing education: A bibliometric analysis and visualization","2023","Nurse Education in Practice","71","","103714","","","","22","10.1016/j.nepr.2023.103714","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85168810150&doi=10.1016%2fj.nepr.2023.103714&partnerID=40&md5=591acbc3cbcba0dc516b3a51ee91955a","Ege University, Nursing Faculty, Department of Fundamentals of Nursing, İzmir, Turkey","Yalcinkaya T., Ege University, Nursing Faculty, Department of Fundamentals of Nursing, İzmir, Turkey; Cinar Yucel S., Ege University, Nursing Faculty, Department of Fundamentals of Nursing, İzmir, Turkey","Aim: This study performed a bibliometric analysis of studies related to mobile learning in the field of nursing education. Methods: The Scopus database was used to determine the most frequently cited studies on mobile learning in nursing education. VOSviewer and Bibliometrix were employed for bibliometric analysis and visualization. Science mapping and performance analysis was adopted from bibliometric analysis techniques. In addition, a synthetic knowledge synthesis approach was used. Results: A total of 234 publications were published in 107 sources in 2002–2023. The publications had 8797 citations, an average of 88 citations per publication. In terms of total link strength (TLS), links, a number of articles and citations, the US led all other countries in the field. Regarding authors, Hwang was the most frequently cited authors (n = 348). According to trend topics analysis, the keywords ""gamification"", ""simulation"", ""attitude"", “clinical competence” and “online learning” have emerged in the field. Conclusion: Research on mobile learning in nursing education has been increasing in recent years. The findings of this study can provide new ideas in the applications of mobile learning in nursing education to researchers or nursing faculties in the field. © 2023 Elsevier Ltd","Bibliometrics analysis; Knowledge synthesis; Mobile learning; Nursing education; Nursing students","Bibliometrics; Clinical Competence; Education, Distance; Education, Nursing; Humans; Learning; article; bibliometrics; clinical competence; e-learning; gamification; human; human experiment; mobile learning; nursing education; nursing student; Scopus; simulation; synthesis; systematic review; bibliometrics; distance learning; learning","","","","","Ege Üniversitesi","We are grateful to Ege University Planning and Monitoring Coordination of Organizational Development and Directorate of Library and Documentation for their support in editing and proofreading service of this study.","Abate K.S., The Effect of podcast lectures on nursing students’ knowledge retention and application, Nurs. Educ. 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Today, 35, 2, pp. e19-e23, (2015); Zayim N., Ozel D., Factors affecting nursing students’ readiness and perceptions toward the use of mobile technologies for learning, CIN Comput. Inform. Nurs., 33, 10, pp. 456-464, (2015); Zupic I., Cater T., Bibliometric methods in management and organization, Organ. Res. Methods, 18, 3, pp. 429-472, (2015)","T. Yalcinkaya; Ege University, Nursing Faculty, Department of Fundamentals of Nursing, İzmir, Turkey; email: turgayyalcinkaya35@gmail.com","","Elsevier Ltd","","","","","","14715953","","","37552905","English","Nurse Educ. Pract.","Article","Final","","Scopus","2-s2.0-85168810150" -"Liu J.; Cui M.; Wang Y.; Wang J.","Liu, Jiye (58421739300); Cui, Meng (55316074700); Wang, Yibing (56095807300); Wang, Jiahe (8445510800)","58421739300; 55316074700; 56095807300; 8445510800","Trends in parthenolide research over the past two decades: A bibliometric analysis","2023","Heliyon","9","7","e17843","","","","4","10.1016/j.heliyon.2023.e17843","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85164448378&doi=10.1016%2fj.heliyon.2023.e17843&partnerID=40&md5=76f7ad11699b84e00786ba9355737374","Department of Family Medicine, Shengjing Hospital of China Medical University, Liaoning, Shenyang, 110000, China; Department of Rehabilitation Medicine, Huludao Central Hospital, Liaoning, Huludao, 125000, China; Department of Hospice Care, Shengjing Hospital of China Medical University, Liaoning, Shenyang, 110004, China; Department of Urology Surgery, Shengjing Hospital of China Medical University, Liaoning, Shenyang, 110000, China","Liu J., Department of Family Medicine, Shengjing Hospital of China Medical University, Liaoning, Shenyang, 110000, China, Department of Rehabilitation Medicine, Huludao Central Hospital, Liaoning, Huludao, 125000, China; Cui M., Department of Hospice Care, Shengjing Hospital of China Medical University, Liaoning, Shenyang, 110004, China; Wang Y., Department of Urology Surgery, Shengjing Hospital of China Medical University, Liaoning, Shenyang, 110000, China; Wang J., Department of Family Medicine, Shengjing Hospital of China Medical University, Liaoning, Shenyang, 110000, China","Parthenolide (PTL) is a new compound extracted from traditional Chinese medicine. In recent years, it has been proven to play an undeniable role in tumors, autoimmune diseases, and inflammatory diseases. Similarly, an increasing number of experiments have also confirmed the biological mechanism of PTL in these diseases. In order to better understand the development trend and potential hot spots of PTL in cancer and other diseases, we conducted a detailed bibliometric analysis. The purpose of presenting this bibliometric analysis was to highlight and inform researchers of the important research directions, co-occurrence relationships and research status in this field. Publications related to PTL research from 2002 to 2022 were extracted on the web of science core collection (WoSCC) platform. CiteSpace, VOSviewers and R package “bibliometrix” were applied to build relevant network diagrams. The bibliometric analysis was presented in terms of performance analysis (including publication statistics, top publishing countries, top publishing institutions, publishing journals and co-cited journals, authors and co-cited authors, co-cited references statistics, citation bursts statistics, keyword statistics and trend topic statistics) and science mapping (including citations by country, citations by institution, citations by journal, citations by author, co-citation analysis, and keyword co-occurrence). The detailed discussion of the results explained the focus and latest trends from the bibliometric analysis. Finally, the current status and shortcomings of the research field on PTLwere clearly pointed out for reference by scholars. © 2023","Anticancer; Antiinflammatory; Apoptosis; Bibliometrics; Parthenolide","","","","","","345 Talent Project of Shengjing Hospital","This study was supported by the 345 Talent Project of Shengjing Hospital. 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Wang; Department of Family Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110000, China; email: wangjh1@sj-hospital.org","","Elsevier Ltd","","","","","","24058440","","","","English","Heliyon","Review","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85164448378" -"Wani J.A.; Ganaie S.A.; Rehman I.U.","Wani, Javaid Ahmad (57211168037); Ganaie, Shabir Ahmad (55745889700); Rehman, Ikhlaq Ur (57208900045)","57211168037; 55745889700; 57208900045","Mapping research output on library and information science research domain in South Africa: a bibliometric visualisation","2023","Information Discovery and Delivery","51","2","","194","212","18","19","10.1108/IDD-10-2021-0115","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85139957969&doi=10.1108%2fIDD-10-2021-0115&partnerID=40&md5=ed2b8d2d55cbeef9152bba95ee8b72f2","Department of Library and Information Science, University of Kashmir, Srinagar, India","Wani J.A., Department of Library and Information Science, University of Kashmir, Srinagar, India; Ganaie S.A., Department of Library and Information Science, University of Kashmir, Srinagar, India; Rehman I.U., Department of Library and Information Science, University of Kashmir, Srinagar, India","Purpose: The purpose of this study is to examine the research output on “library and information science” (LIS) research domain in South Africa. It also highlights the top LIS research organisations, authors, journals, collaboration types and commonly used keywords. This research will aid in the identification of emerging concepts, trends and advances in this subject. Design/methodology/approach: The Web of Science (WoS), an indexing and abstracting database, served as a tool for bibliographical data. By applying advanced search features, the authors curated data from 1989 to 2021 through the WoS subject category WC = (Information Science & Library Science), limiting the scope to the region, CU = (South Africa), which resulted in 1,034 articles. Moreover, the research focuses on science mapping using the R package for reliable analysis. Findings: The findings reveal that the publications have considerably grown over time, indicating significant attention among researchers in LIS. The findings indicate the critical operator’s performance, existing thematic choices and subsequent research opportunities. The primary topical fields of study that emerged from the bibliometric analysis are impact, information, science, model, management, technology, knowledge and education. Pouris and Fourie are the most productive citations, h-index and g-index. The influential institute was The University of Pretoria. Research limitations/implications: The use of the WoS database for data collecting limits this study. Because the WoS was the only citation and abstract database used in this study, bibliometric investigations using other citation and abstract databases like “Scopus”, “Google Scholar” and “Dimension” could be interesting. This study presented a bibliometric summary; nevertheless, a systematic and methodical examination of highly cited LIS research publications could throw more light on the subject. Practical implications: This paper gives valuable information about recent scientific advancements in the LIS and emerging future academic subject prospects. Furthermore, this research work will serve as a reference for researchers in various areas to analyse the evolution of scholarly literature on a particular topic over time. Originality/value: By identifying the standard channels of study in the LIS discipline, and the essential journals, publications, nations, institutions, authors, data sources and networks in this subject, this bibliometric mapping and visualisation provide new perspectives into academic performance. This paper also articulates future research directions in this realm of knowledge. This study is more rigorous and comprehensive in terms of the analytical procedures it uses. © 2022, Emerald Publishing Limited.","Bibliometrics; Bibliometrix-R; Library and information science; Science mapping; South Africa; VOSviewer","","","","","","DST NRF Centre of Excellence in Scientometrics and Science Technology and Innovation Policy SCISTIP; Mr Khan Mohmad Shafi; University of Kashmir","Funding text 1: The data analysis showed that 911 (88.019%) articles do not reflect any funding information. Therefore, there was no funding available for a maximum of research articles. The funding sources for 12% of documents that reflected funding details are: National Research Foundation South Africa endowed to 1.74% papers. The European Commission sponsored 1.06% of documents. National Institutes of Health (NIH), USA invested on 0.87% of research articles. United States Department of Health Human Services supported 0.87% of manuscripts. South African DST NRF Centre of Excellence in Scientometrics and Science Technology and Innovation Policy SCISTIP funded 0.58% of articles. China Scholarship Council sponsored 0.48%. It is pertinent to mention that in South Africa, there are very few indigenous funding sources for researchers (). ; Funding text 2: The authors would like to express special thanks of gratitude to anonymous reviewers for their useful suggestions. Moreover, authors thank Mr Khan Mohmad Shafi (Assistant Professor, Computer Applications – University of Kashmir, India) for his technical support and suggestions. Mr. Khan holds teaching experience of ten years at university level; the interested research areas of Mr. Khan are “natural language processing”, “machine learning”, and “deep learning frameworks”.","Abdullahi I., Kajberg L., Virkus S., Internationalization of LIS education in Europe and North America, New Library World, 108, 1-2, pp. 7-24, (2007); Adams J., The fourth age of research, Nature, 497, 7451, pp. 557-560, (2013); Adisa O.M., Masinde M., Botai J.O., Botai C.M., Bibliometric analysis of methods and tools for drought monitoring and prediction in Africa, Sustainability, 12, 16, (2020); Ahmad K., JianMing Z., Rafi M., Assessing the literature of knowledge management (KM) in the field of library and information science, Information Discovery and Delivery, 47, 1, pp. 35-41, (2019); Ahmad K., Sheikh A., Rafi M., Scholarly research in library and information science: an analysis based on ISI Web of Science, Performance Measurement and Metrics, 21, 1, pp. 18-32, (2020); Aina L.O., Mabawonku I.M., The literature of the information profession in anglophone Africa: characteristics, trend and future directions, Journal of Information Science, 23, 4, pp. 321-326, (1997); Aina L.O., Mooko N.P., Research and publication patterns in library and information science, Information Development, 15, 2, pp. 114-119, (1999); Alemna A.A., The periodical literature of library and information in Africa: 1996-2000, Information Development, 17, 4, pp. 257-261, (2001); Ani O.E., Okwueze E.U., Bibliometric analysis of publication output in library and information science research in Nigerian universities 2000-2014, Nigerian Libraries, 49, 1-2, pp. 8-17, (2016); Ani O.E., Onyancha O.B., An informatrics analysis of research output in Nigeria with special reference to universities: 2000-2010, Mousain, 30, 1, pp. 143-157, (2012); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Arkhipov D.B., Berezkin V.G., Development of analytical chemistry in the latter half of the 20th century (scientometric analysis), Journal of Analytical Chemistry, 57, 7, pp. 581-585, (2002); Asubiaro T.V., Research collaboration landscape of the university of Ibadan biomedical authors between 2006 and 2015, African Journal of Library, Archives and Information Science, 28, 1, pp. 17-31, (2018); Asubiaro T., How collaboration type, publication place, funding and author’s role affect citations received by publications from Africa: a bibliometric study of LIS research from 1996 to 2015, Scientometrics, 120, 3, pp. 1261-1287, (2019); Bailon-Moreno R., Jurado-Alameda E., Ruiz-Banos R., Courtial J.P., Analysis of the field of physical chemistry of surfactants with the unified scienctometric model. 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Wani; Department of Library and Information Science, University of Kashmir, Srinagar, India; email: wanijavaid1@gmail.com","","Emerald Publishing","","","","","","23986247","","","","English","Information Discov. Deliv.","Article","Final","","Scopus","2-s2.0-85139957969" -"Akın M.; Eyduran S.P.; Papageorgiou M.; Bartkiene E.; Rocha J.M.","Akın, Melekşen (56661878900); Eyduran, Sadiye Peral (55666872700); Papageorgiou, Maria (8645438400); Bartkiene, Elena (36169146600); Rocha, Joao Miguel (7202074289)","56661878900; 55666872700; 8645438400; 36169146600; 7202074289","Bibliometric analysis on pseudocereals","2023","Cleaner and Circular Bioeconomy","6","","100062","","","","5","10.1016/j.clcb.2023.100062","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182203817&doi=10.1016%2fj.clcb.2023.100062&partnerID=40&md5=bbc03a05c2d4563a250aface7b7b813a","Department of Horticulture, Iğdır University, Iğdır, 76 000, Turkey; Department of Horticulture, Muğla Sıtkı Koçman University, Fethiye, Turkey; Department of Food Science and Technology, International Hellenic University, Thessaloniki, Greece; Institute of Animal Rearing Technologies, Lithuanian University of Health Sciences, Tilzes St. 18, Kaunas, LT-47181, Lithuania; Department of Food Safety and Quality, Lithuanian University of Health Sciences, Tilzes St. 18, Kaunas, LT-47181, Lithuania; Universidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina – Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, Porto, 4169-005, Portugal; LEPABE – Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto (FEUP), Rua Dr. Roberto Frias, Porto, 4200-465, Portugal; ALiCE – Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto (FEUP), Rua Dr. Roberto Frias, Porto, 4200-465, Portugal","Akın M., Department of Horticulture, Iğdır University, Iğdır, 76 000, Turkey; Eyduran S.P., Department of Horticulture, Muğla Sıtkı Koçman University, Fethiye, Turkey; Papageorgiou M., Department of Food Science and Technology, International Hellenic University, Thessaloniki, Greece; Bartkiene E., Institute of Animal Rearing Technologies, Lithuanian University of Health Sciences, Tilzes St. 18, Kaunas, LT-47181, Lithuania, Department of Food Safety and Quality, Lithuanian University of Health Sciences, Tilzes St. 18, Kaunas, LT-47181, Lithuania; Rocha J.M., Universidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina – Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, Porto, 4169-005, Portugal, LEPABE – Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto (FEUP), Rua Dr. Roberto Frias, Porto, 4200-465, Portugal, ALiCE – Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto (FEUP), Rua Dr. Roberto Frias, Porto, 4200-465, Portugal","A bibliometric analysis on scientific documents regarding pseudocereals was performed. The literature was extracted from Web of Science database with limitations on language and index, resulting in 438 documents published until 2022. The bibliographic data were analyzed using Bibliometrix package and Biblioshiny interface available on R statistical language. The first source on pseudocereals was published in 1982 according to our data collection, and there was an increased trend of publications over the time with annual production above 11 %. The core group consisted of 11 out of 175 journals publishing on the field. Italy made the largest contribution, followed by Spain, Mexico, USA, China, among others. Collaboration network analysis was run to map associations between top countries on pseudocereals research. Six distinct sub-clusters of countries tending to collaborate together were detected. All of the publications of Israel on the area were in collaboration with other countries, whereas Argentina and Turkey published only single country publications. The most commonly used author keywords displayed with the word cloud after pseudocereals were quinoa, amaranth, buckwheat, and gluten-free. Other notable keywords were food composition, antioxidant activity, fermentation, bread, celiac disease, lactic acid bacteria, etc. The objective of the current study is to illustrate emerging trends in journal performance, collaboration networks, research constituents, intellectual structure, and evolutionary nuances of the field, thus also supporting policy development to promote research on pseudocereals utilizing bibliometrics approach. © 2023 The Author(s)","Bibliometric research; Collaboration map; Performance analysis; Science mapping; Social structure; Trend research topics","","","","","","ALiCE, (UIDB/00511/2020 - UIDP/00511/2020); Faculdade de Engenharia, Universidade do Porto, FEUP; European Cooperation in Science and Technology, COST, (LA/P/0045/2020); Fundação para a Ciência e a Tecnologia, FCT; Ministério da Ciência, Tecnologia e Ensino Superior, MCTES, (PTDC/EQU-EQU/28101/2017); Universidade do Porto, U.Porto; European Regional Development Fund, ERDF","This work was performed during a Short-Term Scientific Mission (STSM) on the scope of SOURDOMICS (CA18101) held at the Faculty of Engineering, University of Porto (FEUP), Porto, Portugal, and entitled “Bibliometric assessment on ""pseudocereals"" and ""sourdough"" literature”. This work is based upon the work from COST Action 18101 SOURDOMICS — Sourdough biotechnology network towards novel, healthier and sustainable food and bioprocesses (https://sourdomics.com/; https://www.cost.eu/actions/CA18101/, accessed in 2022-07-15), where the author J.M.R. is the Chair and Grant Holder Scientific Representative, and the author M.A. is the Short-Term Scientific Mission (STSM) Coordinator, the author M.P. is the vice-leader of the working group “Recovery, characterization and selection of autochthonous conventional and non-conventional (pseudo)cereal seeds”, and is supported by COST (European Cooperation in Science and Technology) (https://www.cost.eu/, accessed in 2022-07-15). COST is a funding agency for research and innovation networks. Regarding to the author J.M.R. this work was also financially supported by: (i) LA/P/0045/2020 (ALiCE) and UIDB/00511/2020 - UIDP/00511/2020 (LEPABE) funded by national funds through FCT/MCTES (PIDDAC); and (ii) Project PTDC/EQU-EQU/28101/2017 – SAFEGOAL - Safer Synthetic Turf Pitches with Infill of Rubber Crumb from Recycled Tires, funded by FEDER funds through COMPETE2020 – Programa Operacional Competitividade e Internacionalização (POCI) and by national funds (PIDDAC) through FCT/MCTES. No funding sources to declare.","Aguiar E.V., Santos F.G., Centeno A.C.L.S., Capriles V.D., Influence of pseudocereals on gluten-free bread quality: a study integrating dough rheology, bread physical properties and acceptability, Food Res. 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Informat., 35, 1, pp. 168-185, (2018); Nascimento A.C., Mota C., Coelho I., Gueifao S., Santos M., Matos A.S., Castanheira I., Characterisation of nutrient profile of quinoa (Chenopodium quinoa), amaranth (Amaranthus caudatus), and purple corn (Zea mays L.) consumed in the North of Argentina: proximates, minerals and trace elements, Food Chem., 148, pp. 420-426, (2014); Novotni D., Ganzle M., Rocha J.M., Chapter 5 - Composition and activity of microbiota in sourdough and their effect on bread quality and safety, Trends in Wheat and Bread Making, pp. 129-172, (2021); Pacularu-Burada B., Georgescu L.A., Vasile M.A., Rocha J.M., Bahrim G.-E., Selection of wild lactic acid bacteria strains as promoters of postbiotics in gluten-free sourdoughs, Microorganisms, 8, 5, (2020); Pacularu-Burada B., Turturica M., Rocha J.M., Bahrim G.-E., Statistical approach to potentially enhance the postbiotication of gluten-free sourdough, Appl. Sci., 11, 11, (2021); Pasko P., Barton H., Zagrodzki P., Gorinstein S., Folta M., Zachwieja Z., Anthocyanins, total polyphenols and antioxidant activity in amaranth and quinoa seeds and sprouts during their growth, Food Chem., 115, 3, pp. 994-998, (2009); Paucean A., Man S.M., Chis M.S., Muresan V., Pop C.R., Socaci S.A., Muste S., Use of pseudocereals preferment made with aromatic yeast strains for enhancing wheat bread quality, Foods, 8, 10, (2019); Petrova P., Petrov K., Lactic acid fermentation of cereals and pseudocereals: ancient nutritional biotechnologies with modern applications, Nutrients, 12, 4, (2020); Pirzadah T.B., Malik B., Pseudocereals as super foods of 21st century: recent technological interventions, J. Agric. Food Res., 2, (2020); Core Team R., R: A Language and Environment for Statistical Computing, (2022); Sellami M.H., Pulvento C., Lavini A., Agronomic practices and performances of quinoa under field conditions: a systematic review, Plants, 10, 1, (2020); Thakur P., Kumar K., Dhaliwal H.S., Nutritional facts, bio-active components and processing aspects of pseudocereals: a comprehensive review, Food Biosci., 42, (2021); Thelwall M., Social networks, gender, and friending: an analysis of MySpace member profiles, J. Am. Soc. Inf. Sci. Technol., 59, 8, pp. 1321-1330, (2008); Waltman L., Van Eck N.J., A new methodology for constructing a publication-level classification system of science, J. Am. Soc. Inf. Sci. Technol., 63, 12, pp. 2378-2392, (2012); Wang J., Li X., Wang P., Liu Q., Bibliometric analysis of digital twin literature: a review of influencing factors and conceptual structure, Technol. Anal. Strategic Manag., pp. 1-15, (2022); Xiang C., Wang Y., Liu H., A scientometrics review on nonpoint source pollution research, Ecol. Eng., 99, pp. 400-408, (2017)","M. Akın; Department of Horticulture, Iğdır University, Iğdır, 76 000, Turkey; email: akinmeleksen@gmail.com","","Elsevier B.V.","","","","","","27728013","","","","English","Clean. Circ. Bioeconomy.","Review","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85182203817" -"Olufunke O.; Okuoyo O.","Olufunke, Oladipupo (36543110300); Okuoyo, Otavie (57699217500)","36543110300; 57699217500","A Bibliometric Analysis and Science Mapping of Recommendation Systems Research from 1987 to 2022","2023","2023 International Conference on Science, Engineering and Business for Sustainable Development Goals, SEB-SDG 2023","","","","","","","2","10.1109/SEB-SDG57117.2023.10124525","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85161383124&doi=10.1109%2fSEB-SDG57117.2023.10124525&partnerID=40&md5=51ee436a953decaea53735c272396038","Covenant University, Department of Computer and Information Sciences, Ota, Nigeria","Olufunke O., Covenant University, Department of Computer and Information Sciences, Ota, Nigeria; Okuoyo O., Covenant University, Department of Computer and Information Sciences, Ota, Nigeria","This paper presents a bibliometric analysis and science mapping study of recommendation systems (RS) using VOSviewer and Bibliometrix-R package tools. The study analysed 9,232 Scopus-indexed papers from 1987 to 2022 to uncover publishing trends and evaluate the performance of researchers, journals, articles, institutions and countries in this domain. The study found that the United States, Spain and the United Kingdom produced high-quality research with high citation-to-publication ratios. China had the most publication and the highest level of international collaboration. African countries such as Nigeria, Tunisia, Algeria, Egypt and others lag in publications, institutions, citations, and collaborations with developed countries. Joseph Konstan, John Riedl, Bamshad Mobasher, Robin Burke, Francesco Ricci, and Yehuda Koren were identified as leading researchers in the field. Recommendation systems are crucial for social media, e-commerce, and e-learning and high-performing algorithms are needed to help people find relevant, personalized information. The results of this study could help researchers and scholars find potential collaborators, and understand current trends and future directions in recommender system-related journals more quickly. © 2023 IEEE.","bibliometric analysis; Bibliometrix; Biblioshiny; recommender system; science mapping","Electronic commerce; International cooperation; Mapping; Bibliometrics analysis; Bibliometrix; Biblioshiny; High-quality research; Journal articles; Mapping studies; Performance; Science mapping; Systems research; United kingdom; Recommender systems","","","","","","","Afolabi I.T., Makinde O.S., Oladipupo O.O., Semantic Web mining for Content-Based Online Shopping Recommender Systems, Int. J. Intell. Inf. Technol, 15, 4, pp. 41-56, (2019); Cui Z., Et al., Personalized Recommendation System Based on Collaborative Filtering for IoT Scenarios, IEEE Trans. Serv. Comput, 13, 4, pp. 685-695, (2020); Tiwari S., Kumar S., Jethwani V., Kumar D., Dadhich V., PNTRS: Personalized news and tweet recommendation system, J. Cases Inf. Technol, 24, 3, pp. 1-19, (2022); Zhang Q., Lu J., Jin Y., Artificial intelligence in recommender systems, Complex Intell. Syst, 7, 1, pp. 439-457, (2021); Ebesu T., Shen B., Fang Y., Collaborative memory network for recommendation systems, 41st Int. ACM SIGIR Conf. Res. Dev. Inf. Retrieval, SIGIR, 2018, pp. 515-524, (2018); Felfernig A., Et al., An overview of recommender systems in the internet of things, J. Intell. Inf. Syst, 52, 2, pp. 285-309, (2019); Altulyan M., Yao L., Wang X., Huang C., Kanhere S.S., Sheng Q.Z., Recommender Systems for the Internet of Things: A Survey, (2020); Yu X., Wei D., Chu Q., Wang H., The Personalized Recommendation Algorithms in Educational Application, Proc.-9th Int. Conf. Inf. Technol. Med. Educ. ITME, 2018, pp. 664-668, (2018); Aditya P.H., Budi I., Munajat Q., A comparative analysis of memory-based and model-based collaborative filtering on the implementation of recommender system for E-commerce in Indonesia: A case study PT X, 2016 Int. Conf. Adv. Comput. Sci. Inf. Syst. ICACSIS, 2016, pp. 303-308, (2017); Li K., Zhou X., Lin F., Zeng W., Alterovitz G., Deep probabilistic matrix factorization framework for online collaborative filtering, IEEE Access, 7, pp. 56117-56128, (2019); Tarus J.K., Niu Z., Kalui D., A hybrid recommender system for e-learning based on context awareness and sequential pattern mining, Soft Comput, 22, 8, pp. 2449-2461, (2018); Al-Bashiri H., Abdulgabber M.A., Romli A., Kahtan H., An improved memory-based collaborative filtering method based on the TOPSIS technique, PLoS One, 13, 10, (2018); Jiang L., Liu L., Yao J., Shi L., A hybrid recommendation model in social media based on deep emotion analysis and multi-source view fusion, (2020); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: An overview and guidelines, J. Bus. Res, 133, pp. 285-296, (2021); Moral-Munoz J.A., Et al., Software tools for conducting bibliometric anMoral-muñoz, J. A., Herrera-viedma, E., Santisteban-espejo, Software tools for conducting bibliometric analysis in science: An, pp. 1-20, (2020); Diodato V., Dictionnary of Bibliometrics, (1994); Gnoli C., Hjorland B., Encyclopedia of Knowledge Organization: Science mapping (IEKO), 26, (2021); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr, 11, 4, pp. 959-975, (2017); Van Eck N.J., Waltman L., Manual de VOSviewer, (2021); Fan J., Gao Y., Zhao N., Dai R., Zhang H., Feng X., Bibliometric Analysis on COVID-19: A Comparison of Research between English and Chinese Studies Data Source and Search Strategy, 8, pp. 1-10, (2020); Perianes-Rodriguez A., Ludo W., Van Eck N.J., Constructing bibliometric networks: A comparison between full and fractional counting, J. Informetr, 10, 4, pp. 1178-1195, (2016); Feng Y., Zhu Q., Lai K.H., Corporate social responsibility for supply chain management: A literature review and bibliometric analysis, J. Clean. Prod, 158, pp. 296-307, (2017); Maphosa V., Maphosa M., Fifteen Years of Recommender Systems Research in Higher Education: Current Trends and Future Direction, Appl. Artif. Intell, 37, 1, (2023); Anandhan A., Ismail M.A., Social Media Recommender Systems (SMRS ): A Bibliometric Analysis Study 2000-2021, IEEE Access, 10, pp. 35479-35497, (2022); Sharma S., Gupta K., Gupta D., Recommender system: A bibliometric analysis, IOP Conf. Ser. Mater. Sci. Eng, 1022, 1, (2021); Yin X., Wang H., Wang W., Zhu K., Task recommendation in crowdsourcing systems: A bibliometric analysis, Technol. Soc, 63, (2020); Afolabi I.T., Ayo A., Odetunmibi O.A., Academic Collaboration Recommendation for Computer Science Researchers Using Social Network Analysis, Wirel. Pers. Commun, 121, 1, pp. 487-501, (2021); Nam L.N.H., Towards comprehensive approaches for the rating prediction phase in memory-based collaborative filtering recommender systems, Inf. Sci. (Ny), 589, 227, pp. 878-910, (2022); Karabadji N.E.I., Beldjoudi S., Seridi H., Aridhi S., Dhifli W., Improving memory-based user collaborative filtering with evolutionary multi-objective optimization, Expert Syst. Appl, 98, pp. 153-165, (2018); Jeong C., Kang S., Chung K., Real-Time Recommendation System for Online Broadcasting Advertisement, pp. 413-416, (2021); Pocs M., Model-Based Recommendation System | Towards Data Science; Isinkaye F.O., Folajimi Y.O., Ojokoh B.A., Recommendation systems: Principles, methods and evaluation, Egypt. Informatics J, 16, 3, pp. 261-273, (2015); Wang H., Zhao M., Xie X., Li W., Guo M., Knowledge graph convolutional networks for recommender systems, Web Conf. 2019-Proc. World Wide Web Conf. WWW, 2019, pp. 3307-3313, (2019); Ying R., He R., Chen K., Eksombatchai P., Hamilton W.L., Leskovec J., Graph convolutional neural networks for web-scale recommender systems, Proc. ACM SIGKDD Int. Conf. Knowl. Discov. Data Min, pp. 974-983, (2018); Wu J., Et al., Self-supervised Graph Learning for Recommendation, 1, 1, (2021); Mongeon P., Paul-Hus A., The journal coverage of Web of Science and Scopus: A comparative analysis, Scientometrics, 106, 1, pp. 213-228, (2016); Baas J., Schotten M., Plume A., Cote G., Karimi R., Scopus as a curated, high-quality bibliometric data source for academic research in quantitative science studies, Quant. Sci. Stud, 1, 1, pp. 377-386, (2020); Falagas M.E., Pitsouni E.I., Malietzis G.A., Pappas G., Comparison of PubMed, Scopus, Web of Science, and Google Scholar: Strengths and weaknesses, FASEB J, 22, 2, pp. 338-342, (2008); Wang Q., Waltman L., Large-scale analysis of the accuracy of the journal classification systems of Web of Science and Scopus, J. Informetr, 10, 2, pp. 347-364, (2016); Wang M., Chai L., Three new bibliometric indicators/approaches derived from keyword analysis, Scientometrics, 116, 2, pp. 721-750, (2018); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: How great is the impact, Scientometrics, 105, 3, pp. 1809-1831, (2015); Koren Y., Bell R., Volinsky C., Matrix Factorization Techniques for Recommender Systems, IEEE Comput. Soc, 30, 7, pp. 489-503, (2009); Burke R., Hybrid Recommender Systems: Survey and Experiments, User Model. User-adapt. Interact, 12, 4, pp. 331-370, (2002); Bobadilla J., Ortega F., Hernando A., Gutierrez A., Recommender systems survey, Knowledge-Based Syst, 46, pp. 109-132, (2013); Schafer J.B., Konstan J., Riedl J., Recommender Systems in e-Commerce, ACM Int. Conf. Proceeding Ser, pp. 209-212, (1999); Cheng H.T., Et al., Wide & deep learning for recommender systems, ACM Int. Conf. Proceeding Ser, 15, pp. 7-10, (2016); Hao M., Zhou D., Liu C., Lyu M.R., King I., Recommender systems with social regularization, Proc. 4th ACM Int. Conf. Web Search Data Mining, WSDM, 2011, pp. 287-296, (2011); Wang H., Wang N., Yeung D.-Y., Collaborative Deep Learning for Recommender Systems, Proc. ACM SIGKDD Int. Conf. Knowl. Discov. Data Min, 9, pp. 22053-22061, (2015); Adomavicius G., Sankaranarayanan R., Sen S., Tuzhilin A., Incorporating Contextual Information in Recommender Systems Using a Multidimensional Approach, ACM Trans. Inf. Syst, 23, 1, pp. 103-145, (2005); Massa P., Avesani P., Trust-aware Recommender Systems, RecSys'08 Proc. 2008 ACM Conf. Recomm. Syst, pp. 17-24, (2007); Lu J., Wu D., Mao M., Wang W., Zhang G., Recommender system application developments: A survey, Decis. Support Syst, 74, pp. 12-32, (2015)","","","Institute of Electrical and Electronics Engineers Inc.","","2023 International Conference on Science, Engineering and Business for Sustainable Development Goals, SEB-SDG 2023","5 April 2023 through 7 April 2023","Omu-Aran","188904","","979-835032478-5","","","English","Int. Conf. Sci., Eng. Bus. Sustain. Dev. Goals, SEB-SDG","Conference paper","Final","","Scopus","2-s2.0-85161383124" -"Abouk F.; Arastoopoor S.; Khajavi R.","Abouk, Farahnaz (59544597800); Arastoopoor, Sholeh (35208111900); Khajavi, Reza (56531827900)","59544597800; 35208111900; 56531827900","Knowledge Structure of Seismology in Materials and Energy Fields From 2010 to 2020: A Science Mapping Study","2023","Scientometrics Research Journal","9","2","","559","592","33","0","10.22070/rsci.2023.16194.1589","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85217049727&doi=10.22070%2frsci.2023.16194.1589&partnerID=40&md5=2583fe6c9a653adc8857177bd385d1e9","Ferdowsi University of Mashhad, Iran","Abouk F., Ferdowsi University of Mashhad, Iran; Arastoopoor S., Ferdowsi University of Mashhad, Iran; Khajavi R., Ferdowsi University of Mashhad, Iran","Purpose: The main objective of this paper is to analyze the intellectual framework of seismology in two distinct domains: materials and energy, from 2010 to 2020, using a science mapping technique. These two fields were selected based on their investment rate by international institutions compared to other areas of seismology. Moreover, this study also focused on the evolution of different clusters and subclusters that were formed or transformed into other clusters during the time span of the study. Methodology: To this end, scientometrics approach and science mapping technique used for creating an intellectual structure of seismology through a co-word analysis. Both strategic and theme evolution diagrams were prepared using R's Bibliometrix package. Strategic diagrams pinpointed the place of different clusters in four areas of Motor themes, Highly developed and isolated themes, Emerging or declining themes, and Basic and transversal themes. Sankey diagrams were also utilized in order to depict the evolution of different clusters through time. The time frames of these graphs were determined automatically by the R Bibliometrix package. Findings: the results showed that the number of papers in materials' field is higher than energy field and this number is ascending in both fields. 4 clusters were identified in the field of materials and each of them is placed in one of the 4 tiers of the strategic diagram. ―Earthquakes‖ is placed in Motor themes, while ―reinforced concretes‖ cluster is placed somewhere between motor themes and Basic and transversal themes. The ""energy dissipation"" cluster is classified under Highly advanced and isolated themes, while ""walls (structural partitions)"" falls under Emerging or declining themes. As for the energy field, six clusters were identified, but they were divided between two different quadrants of the strategic dia gram. The clusters ""earthquakes,"" ""earthquake event,"" and ""Nuclear power plant"" were placed in the Motor themes quadrant, while ""Wenchuan earthquake,"" ""forecasting,"" and ""stochastic systems"" were fitted in the Emerging or declining themes quadrant. Another interesting finding of this study based on the Sankey diagrams is that during 2010 to 2020 in the field of materials at least 20 different clusters were formed and reformed or dissolved into other clusters which means that this field is somehow active and during 2014 to 2017 has experienced lots of changes and reforms among its sub-clusters. As for the energy field, 21 clusters were identified, each of which experienced some sort of transformation or even devastation. During 2017 and 2018, this field experienced its most active era. If we compare the results of both fields, we can infer that the materials field has undergone more branching than the energy field. In 2010, four clusters were identified in the materials field, whereas in 2020, the number of identified clusters increased to seven. However, in the energy field in 2010, 7 clusters were identified. However, by 2020, the number of clusters had declined to 5. The third part of this study's findings focuses on the highly cited papers in these two fields. The results show that the top ten most cited papers in the materials field are divided into eight different clusters. Among them concretes and earthquake resistance are placed among Motor themes and earthquake engineering and reinforcement clusters are fitted in Basic and transversal themes. While columns(structural) and separation clusters are placed in Emerging or declining themes. As for the energy field, these top 10 cited papers are divided into six clusters. Nuclear energy cluster is considered to be a Motor theme but risk assessment and seismology is placed in Highly developed and isolated themes. However, hydrolic fracturing and deformation clusters are fitted in Basic and transversal themes and earthquakes cluster is among Emerging or declining themes. Conclusion: based on the results of this study, it is evident that thematic diversity in materials field is more than energy field. This trend is also observed among scientific products with higher citation rates. As for the evolution of clusters in both fields, the results indicate that the materials field has undergone more branching than the energy field. © 2023, Shahed University. All rights reserved.","energy in seismology; materials in seismology; science mapping; theme evolution","","","","","","","","Abouk F., Mapping the Knowledge Structure of Seismology, (2020); Adeniyi O., Perera S., Collins A., Review of finance and investment in disaster resilience in the built environment, International Journal of Strategic Property Management, 20, 3, pp. 224-238, (2016); AlAjarmeh O. S., Manalo A. C., Benmokrane B., Karunasena K., Ferdous W., Mendis P., Hollow concrete columns: Review of structural behavior and new designs using GFRP reinforcement, Engineering Structures, 203, 15, (2020); Anil S., Kademani B. S., Garg R. G., Kumar V., Scientometric mapping of Tsunami publications: a citation based study, Malaysian Journal of Library & Information Science, 15, 1, pp. 23-40, (2010); Asadi M., Ghaderi S., Thirty-nine years of Iran’s scientific products in the field of Geophysics, Journal of the Earth and Space Physics, 41, 1, pp. 147-166, (2015); Asnafi A., Pakdaman Naeini M., A Survey on scientific collaboration rate in earthquake engineering and seismology researcher in SEE international conference during 1991-2011, Iranian Journal of Engineering Education, 16, 64, pp. 135-150, (2015); Behrens J., Lovholt F., Jalayer F., Lorito S., Salgado-Galvez M. A., Sorensen M., Vyhmeister E., Probabilistic Tsunami Hazard and Risk Analysis: A Review of Research Gaps, Frontiers in Earth Science, 9, 114, pp. 628-772, (2021); Bendle L.J., Patterson I., Network Density, Centrality, and Communication in a Serious Leisure Social World, Annals of Leisure Research, 11, 1-2, pp. 1-19, (2008); Bigdeloo E., Intellectual Structure of Knowledge in information retrieval: A Co-Word Analysis, Scientometrics Research Journal, (2022); Bin C., Weiqi C., Shaoling C., Chunxia H., Visual Analysis of Research Hot Spots, Characteristics, and Dynamic Evolution of International Competitive Basketball Based on Knowledge Mapping, SAGE Open, (2021); Borner K., Atlas of science: Visualizing what we know, (2010); Brogi A., Capezzuoli E., Karabacak V., Alcicek M. C., Luo L., Fissure Ridges: A Reappraisal of Faulting and Travertine Deposition (Travitonics), Geosciences, 11, 7, (2021); Choi H. T., Kim T. R., Necessity of management for minor earthquake to improve public acceptance of nuclear energy in South Korea, Nuclear Engineering and Technology, 50, 3, pp. 494-503, (2018); Cibulka S., Giljum S., Towards a comprehensive framework of the relationships between resource footprints, quality of life, and economic development, Sustainability, 12, 11, (2020); Cobo M. J., Lopez-Herrera A. G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: A practical application to the Fuzzy Sets Theory field, Journal of Informetrics, 5, 1, pp. 146-166, (2011); Cobo M. J., Lopez-Herrera A. G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Emmer A., Geographies and scientometrics of research on natural hazards, Geosciences (Switzerland), 8, 10, (2018); Fallah M., Ghorobi A., Noruzi A., Jafari A., Scientometric Study of Scientific Publications in Seismology based on Web of Science, Rahyaft, 28, 72, pp. 61-76, (2019); Flachenecker F., Rentschler J., de Kleuver W., Monitoring Resource Efficiency Developments: Indicators, Data, and Trends, Investing in Resource Efficiency, pp. 31-50, (2018); Gizzi F. T., Potenza M. R., The Scientific Landscape of November 23rd, 1980 Irpinia-Basilicata Earthquake: Taking Stock of (Almost) 40 Years of Studies, Geosciences, 10, 12, (2020); Grossi L., Heim S., Waterson M., A vision of the European energy future? The impact of the German response to the Fukushima earthquake, (2014); Hassanzadeh M., Zandian F., Ahmadi Meinagh S., Mapping the Cognitive Structure and Its Evolution in Knowledge and Information Science: A Text Mining Approach (2004-2013), Scientometrics Research Journal, 4, 8, pp. 123-142, (2018); He W., Liu X., Qiu J., Liu J., Chen J., Zhang C., Collaborative contribution networks and hotspot evolution in earthquake, Environmental Earth Sciences, 80, 6, pp. 1-14, (2021); Hu Y. X., Liu S. C., Dong W., Earthquake engineering, (1996); Liu X., A bibliometric study of earthquake research. 1900-2010, Scientometrics, 92, 3, pp. 747-765, (2012); May P. J., Burby R. J., Kunreuther H., Policy design for earthquake hazard mitigation: Lessons from energy conservation, radon reduction, and termite control, Earthquake spectra, 14, 4, pp. 629-650, (1998); Moya-Anegon F., Vargas-Quesada B., Herrero-Solana V., Chinchilla-Rodriguez Z., Corera-Alvarez E., Munoz-Fernandez F. J., A new technique for building maps of large scientific domains based on the cocitation of classes and categories, Scientometrics, 61, 1, pp. 129-145, (2004); Najjar Lashgari S., Zarei H., Khalkhali A., Pali S., Mapping the Intellectual Structure in the Field of Educational Management in Iran: Co-Word Analysis, Scientometrics Research Journal, 9, 1, pp. 387-408, (2023); Nor A. H. M., Sanik M. E., Salim S., Kaamin M., Osman M. H., Fuzairi N., Alia A., Qurratu'Ain N., A Systematic Literature Review on Earthquake Detector, Multidisciplinary Applied Research and Innovation, 2, 2, pp. 48-59, (2021); Noyons E. C. M., Van Raan A., Integrating research performance analysis and science mapping, Scientometrics, pp. 591-604, (1999); Odabasi O., Kohrangi M., Bazzurro P., Seismic collapse risk of reinforced concrete tall buildings in Istanbul, Bulletin of Earthquake Engineering, pp. 1-27, (2021); Okada Y., Kasahara K., Hori S., Obara K., Sekiguchi S., Fujiwara H., Yamamoto A., Recent progress of seismic observation networks in Japan—Hi-net, F-net, K-NET and KiK-net, Earth, Planets and Space, 56, pp. xv-xxviii, (2004); Ross M., Larson E. D., Williams R. H., Energy demand and materials flows in the economy, Energy, 12, 10-11, pp. 953-967, (1987); Simon J., Bracci J. M., Gardoni P., Seismic response and fragility of deteriorated reinforced concrete bridges, Journal of Structural Engineering, 136, 10, pp. 1273-1281, (2010); Steinberger J. K., Krausmann F., Material and energy productivity, Environmental science & technology, 45, 4, pp. 1169-1176, (2011); Wagner C., Leydesdorff L., Seismology as a case study of distributed collaboration in science, Scientometrics, 58, 1, pp. 91-114, (2003); Wang C., Wu J., He X., Ye M., Liu W., Tang R., Emerging trends and new developments in disaster research after the 2008 Wenchuan earthquake, International journal of environmental research and public health, 16, 1, (2019); Wu X., Chen X., Zhan F. B., Hong S., Global research trends in landslides during 1991–2014: a bibliometric analysis, Landslides, 12, pp. 1215-1226, (2015); Yousefi Khoraem M., Gasemi H., Se talani F., Keshavarz Turk E., Mousakhani M., Clustering and mapping the 40-year trend of foresight research, Future study Management, 30, 4, pp. 41-54, (2020); Zandi Ravan N., davarpanah M., fattahi R., Science Production Mapping in Iran, based on the Articles Indexed in Sciencefor Scientific Information (SCI-E), Library and Information Science Research, 7, 1, pp. 5-26, (2017); Zavaraqi R., Hamdipour A., Identifying the scientific capabilities and competencies of the University of Tabriz based on its social, cognitive and intellectual capacities, Scientometrics Research Journal, 9, 1, pp. 43-74, (2020); Zhang Q., Lu Q., Ye X., Xu S., Lin L. K., Ye Q., Zeng A., Did the 2008 Wenchuan earthquake trigger a change in the conduct of research on seismic risk?, Safety science, 125, (2020)","S. Arastoopoor; Ferdowsi University of Mashhad, Iran; email: arastoopoor@um.ac.ir","","Shahed University","","","","","","24233773","","","","Persian","Scientometr. Res. J.","Article","Final","","Scopus","2-s2.0-85217049727" -"Prakash S.; Agrawal A.; Singh R.; Singh R.K.; Zindani D.","Prakash, Surya (57226556562); Agrawal, Anubhav (57139512600); Singh, Ranbir (59602279000); Singh, Rajesh Kumar (57219456056); Zindani, Divya (57194034953)","57226556562; 57139512600; 59602279000; 57219456056; 57194034953","A decade of grey systems: theory and application – bibliometric overview and future research directions","2023","Grey Systems","13","1","","14","33","19","19","10.1108/GS-03-2022-0030","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85132791541&doi=10.1108%2fGS-03-2022-0030&partnerID=40&md5=519683f0fc08eb536f0884db48a276a7","School of Pharma Management, IIHMR University, Jaipur, India; ECE Department, BML Munjal University, Gurgaon, India; Department of Mechanical Engineering, BML Munjal University, Gurgaon, India; Department of Operations Management, Management Development Institute Gurgaon, Gurgaon, India; Department of Mechanical Engineering, SSN College of Engineering, Chennai, India","Prakash S., School of Pharma Management, IIHMR University, Jaipur, India; Agrawal A., ECE Department, BML Munjal University, Gurgaon, India; Singh R., Department of Mechanical Engineering, BML Munjal University, Gurgaon, India; Singh R.K., Department of Operations Management, Management Development Institute Gurgaon, Gurgaon, India; Zindani D., Department of Mechanical Engineering, SSN College of Engineering, Chennai, India","Purpose: Grey Systems: Theory and Application (GSTA) journal started publication in 2011 and completed a decade in 2021. The purpose of this study is to provide a detailed bibliometric analysis of the articles published in GSTA and their content primary trends and themes. Design/methodology/approach: This study uses the Web of Science (WoS) database to analyze the content of published articles. A range of bibliometric analyses and indicators are applied to analyze the GSTA article content using science mapping tools of the Bibliometrix package in the R environment. Findings: The GSTA publishes around 28 articles each year with citations of this work steadily growing over time. The impact of these publications is measured as total mean citations which increased from 0 to 11. The journal has attracted contributors from around the globe, most often affiliated with China, India and Europe. Thematic evolution of the journal's themes reveals that it has expanded its scope to include topics such as relational analysis, decision making, incidence analysis, and forecasting, hybrid grey-fuzzy or grey-rough modeling, etc. Research limitations/implications: The study is majorly based on GSTA data available on the WoS database. Originality/value: This study provides the first overview of GSTA's publication and citation trends as well as the evolution of its thematic structure. It also suggests future directions that the journal might take to strengthen its position. © 2022, Emerald Publishing Limited.","Bibliometric analysis; Grey systems; Grey theory; Literature review; Retrospective analysis","Publishing; System theory; Bibliometric; Bibliometrics analysis; Future research directions; Gray system; Gray system theory; Grey theory; Literature reviews; Retrospective analysis; System applications; Web of Science; Decision making","","","","","","","Andersen N., Mapping the expatriate literature: a bibliometric review of the field from 1998 to 2017 and identification of current research fronts, International Journal of Human Resource Management, 32, 22, pp. 4687-4724, (2019); Baker H.K., Kumar S., Pattnaik D., Twenty-five years of the journal of corporate finance: a scientometric analysis, Journal of Corporate Finance, 66, (2021); Brooke B., Nathan H., Pawlik T., Trends in the quality of highly cited surgical research over the past 20 years, Annals of Surgery, 249, pp. 162-167, (2009); Burton B., Kumar S., Pandey N., Twenty-five years of the European Journal of Finance (EJF): a retrospective analysis, The European Journal of Finance, 26, 18, pp. 1817-1841, (2020); Camelia D., Grey systems theory in economics – bibliometric analysis and applications' overview, Grey Systems: Theory and Application, 5, 2, pp. 244-262, (2015); Chang P.L., Hsieh P.N., Bibliometric overview of operations research/management science research in Asia, Asia-Pacific Journal of Operational Research, 25, 2, pp. 217-241, (2008); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science mapping software tools: review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, pp. 1382-1402, (2011); Comerio N., Strozzi F., Tourism and its economic impact: a literature review using bibliometric tools, Tourism Economics, 25, 1, pp. 109-131, (2019); De Moya-Anegon F., Chinchilla-Rodriguez Z., Vargas-Quesada B., Corera-Alvarez E., Munoz-Fernandez F., Gonzalez-Molina A., Coverage analysis of Scopus: a journal metric approach, Scientometrics, 73, pp. 53-78, (2007); Deng J.L., Grey Control Systems, (1985); Deng G.F., Lin W.T., Citation analysis and bibliometrics approach for ant colony optimization from 1996 to 2010, Expert Systems with Applications, 39, 3, pp. 6229-6237, (2012); Donthu N., Kumar S., Pandey N., A retrospective evaluation of marketing intelligence and planning: 1983-2019, Marketing Intelligence and Planning, 39, 1, pp. 48-73, (2020); Donthua N., Kumarbe S., Mukherjeec D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Du Y., Teixeira A.C., A bibliometric account of Chinese economics research through the lens of the China economic review, China Economic Review, 23, 4, pp. 743-762, (2012); Jin J., Yu Z., Mi C., Commercial bank credit risk management based on grey incidence analysis, Grey Systems: Theory and Application, 2, 3, pp. 385-394, (2012); Khan M.A., Pattnaik D., Ashraf R., Ali I., Kumar S., Donthu N., Value of special issues in the Journal of Business Research: a bibliometric analysis, Journal of Business Research, 125, pp. 295-313, (2021); Kumar P.K., Suresh, Author productivity and the application of Lotka's Law in LIS publications, Annals of Library and Information Studies (ALIS), 64, 4, pp. 234-241, (2018); Kumar S., Surekha R., Lim W.M., Mangla S.K., Goyal N., What do we know about business strategy and environmental research? Insights from Business Strategy and the Environment, Business Strategy and the Environment, 30, 8, pp. 3454-3469, (2021); Kumar S., Pandey N., Burton B., Sureka R., Research patterns and intellectual structure of Managerial Auditing Journal: a retrospective using bibliometric analysis during 1986-2019, Managerial Auditing Journal, 36, 2, pp. 280-313, (2021); Laengle S., Merigo J.M., Miranda J., Slowinski R., Bomze I., Borgonovo E., Dyson R.G., Oliveira J.F., Teunter R., Forty years of the European journal of operational research: a bibliometric overview, European Journal of Operational Research, 262, 3, pp. 803-816, (2017); Li K., Yan E., Co-mention network of R packages: scientific impact and clustering structure, Journal of Informetrics, 12, 1, pp. 87-100, (2018); Liu S., Xie N., Forrest J., Novel models of grey relational analysis based on visual angle of similarity and nearness, Grey Systems: Theory and Application, 1, 1, pp. 8-18, (2011); Liu S., Fang Z., Yang Y., Forrest J., General grey numbers and their operations, Grey Systems: Theory and Application, 2, 3, pp. 341-349, (2012); Liu S., Forrest J., Yang Y., A brief introduction to grey systems theory, Grey Systems: Theory and Application, 2, 2, pp. 89-104, (2012); Liu S., Yang Y., Xie N., Forrest J., New progress of grey system theory in the new millennium, Grey Systems: Theory and Application, 6, 1, pp. 2-31, (2016); Merigo J.M., Gil-Lafuente A.M., Yager R.R., An overview of fuzzy research with bibliometric indicators, Applied Soft Computing, 27, pp. 420-433, (2015); Mingers J., Leydesdorff L., A review of theory and practice in scientometrics, European Journal of Operational Research, 246, pp. 1-19, (2015); Pan W., Jian L., Liu T., Grey system theory trends from 1991 to 2018: a bibliometric analysis and visualization, Scientometrics, 12, 3, pp. 1407-1434, (2019); Pawlak Z., Rough sets, International Journal of Computer and Information Sciences, 11, 5, pp. 341-356, (1982); Persson O., Danell R., Schneider J.W., How to use Bibexcel for various types of bibliometric analysis, Celebrating Scholarly Communication Studies: A Festschrift for Olle Persson at His 60th Birthday, 5, pp. 9-24, (2009); Prakash S., Kumar S., Soni G., Mahto R.V., Pandey N., A decade of the international journal of lean six sigma: bibliometric overview, International Journal of Lean Six Sigma, 13, 2, pp. 295-341, (2022); Pulwasha M.I., Ali F., Faisaluddin M., Khayyat A., De Sa M.D.G., Rao T., A bibliometric analysis of the top 30 most-cited articles in gestational diabetes mellitus literature (1946-2019), Cureus, 11, 2, pp. 1-12, (2019); Scarlat E., Delcea C., Complete analysis of bankruptcy syndrome using grey systems theory, Grey Systems: Theory and Application, 1, 1, pp. 19-32, (2011); Shuaib W., Khan M., Shahid H., Valdes E., Alweis R., Bibliometric analysis of the top 100 cited cardiovascular articles, American Journal of Cardiology, 115, pp. 972-981, (2015); Wang C., Lim M.K., Lyons A., Twenty years of the international journal of logistics research and applications: a bibliometric overview, International Journal of Logistics Research and Applications, 22, 3, pp. 304-323, (2019); Xu Z., Yu D., A Bibliometrics analysis on big data research (2009-2018), Journal of Data, Information and Management, 1, pp. 3-15, (2019); Xu X., Chen X., Jia F., Brown S., Gong Y., Xu Y., Supply chain finance: a systematic literature review and bibliometric analysis, International Journal of Production Economics, 204, pp. 160-173, (2018); Yin M.S., Fifteen years of grey theory research: a historical review and bibliometric analysis, Expert Systems with Applications, 40, pp. 2767-2775, (2013); Yue H., Liu S., Grey system theory in China: a bibliometrics analysis, IEEE International Conference on Grey Systems and Intelligent Services (GSIS 2009), pp. 564-569, (2009); Zadeh L.A., Fuzzy sets, Information and Control, 8, pp. 338-353, (1965); Zhang Q., Chen R., Application of metabolic GM (1,1) model in financial repression approach to the financing difficulty of the small and medium-sized enterprises, Grey Systems: Theory and Application, 4, 2, pp. 311-320, (2014); Liu S., Yang Y., Cao Y., Xie N., A summary on the research of GRA models, Grey Systems: Theory and Application, 3, 1, pp. 7-15, (2013); Rahimnia F., Moghadasian M., Mashreghi E., Application of grey theory approach to evaluation of organizational vision, Grey Systems: Theory and Application, 1, 1, pp. 33-46, (2011)","S. Prakash; School of Pharma Management, IIHMR University, Jaipur, India; email: suryayadav8383@gmail.com","","Emerald Publishing","","","","","","20439377","","","","English","Grey. Syst.","Review","Final","","Scopus","2-s2.0-85132791541" -"Ibrahim A.; Kumar G.","Ibrahim, Arish (58452238600); Kumar, Gulshan (21733781200)","58452238600; 21733781200","A bibliometric analysis on green Lean Six Sigma based on Scopus data using Biblioshiny","2023","International Journal of Six Sigma and Competitive Advantage","14","4","","371","383","12","1","10.1504/IJSSCA.2023.134460","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175322333&doi=10.1504%2fIJSSCA.2023.134460&partnerID=40&md5=e63a4c03798472f2548e667428d09cc0","Department of Mechanical Engineering, BITS Pilani, Dubai Campus, Dubai, United Arab Emirates","Ibrahim A., Department of Mechanical Engineering, BITS Pilani, Dubai Campus, Dubai, United Arab Emirates; Kumar G., Department of Mechanical Engineering, BITS Pilani, Dubai Campus, Dubai, United Arab Emirates","This study aims to explore the research landscape of green Lean Six Sigma from a bibliometric perspective. The analysis was conducted over the dataset extracted from Scopus database using Biblioshiny app, a web-interface for bibliometrix. Bibliometrix is an open-source tool for executing science mapping analysis of literature. This study is mainly focused on the application of bibliometric approach to analyse the research progress in the field of green Lean Six Sigma through the identification of research trends, authors’ productivity, collaboration, co-occurrence, topmost contributions and trending themes. The results indicate that publications evolved initially in 2013 and the major contributors in this research area are from India. Enablers, barriers and application of green Lean Six Sigma in manufacturing sector are identified as the main driving theme for the future research. This study contributes to the field by presenting research status, thematic focus, and research hotspots along with future direction. © 2023 Inderscience Enterprises Ltd.. All rights reserved.","bibliometric analysis; Biblioshiny; green Lean Six Sigma; lean manufacturing; R programming; Scopus; Six Sigma","","","","","","","","Ibrahim A., Kumar G., A bibliometric analysis on green Lean Six Sigma based on Scopus data using Biblioshiny, Int. J. Six Sigma and Competitive Advantage, 14, 4, pp. 371-383, (2023); Antony J., Snee R., Hoerl R., Lean Six Sigma: yesterday, today and tomorrow, International Journal of Quality & Reliability Management, 34, 7, pp. 1073-1093, (2017); Cherrafi A., Elfezazi S., Chiarini A., Mokhlis A., Benhida K., The integration of lean manufacturing, Six Sigma and sustainability: a literature review and future research directions for developing a specific model, Journal of Cleaner Production, 139, pp. 828-846, (2016); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); De Freitas J.G., Costa H.G., Ferraz F.T., Impacts of Lean Six Sigma over organizational sustainability: a survey study, Journal of Cleaner Production, 156, pp. 262-275, (2017); Garza-Reyes J., Green lean and the need for Six Sigma, International Journal of Lean Six Sigma, 6, 3, pp. 226-248, (2015); Gholami H., Hussain K., Green, lean, Six Sigma barriers at a glance: a case from the construction sector of Pakistan, Business Strategy and the Environment, 30, 4, (2019); Ioannidis J.P., Baas J., Klavans R., Boyack K.W., A standardized citation metrics author database annotated for scientific field, PLoS Biology, 17, 8, pp. 3000384-3000384, (2019); Ioannis B., Arturo G.R.J., Vikas K., The impact of lean methods and tools on the operational performance of manufacturing organizations, International Journal of Production Research, 52, 18, pp. 5346-5366, (2014); Kaswan M.S., Rathi R., Analysis and modeling the enablers of Green Lean Six Sigma implementation using interpretive structural modeling, Journal of Cleaner Production, 231, 2019, pp. 1182-1191, (2019); Kaswan M.S., Rathi R., Investigating the enablers associated with implementation of green Lean Six Sigma in manufacturing sector using best worst method, Clean Technologies and Environmental Policy, 22, 4, pp. 865-876, (2020); Kaswan M.S., Rathi R., Green Lean Six Sigma for sustainable development: Integration and framework, Environmental Impact Assessment Review, 83, 2020, (2020); Kaswan M.S., Rathi R., Khanduja D., Singh M., Life cycle assessment framework for sustainable development in manufacturing environment, Advances in Intelligent Manufacturing. Lecture Notes in Mechanical Engineering, pp. 103-113, (2020); Kumar S., Kumar N., Haleem A., Conceptualisation of sustainable green Lean Six Sigma: an empirical analysis, International Journal of Business Excellence, 8, 2, pp. 210-250, (2015); Kumar S., Luthra S., Govindan K., Kumar N., Haleem A., Barriers in green Lean Six Sigma product development process: an ISM approach, Production Planning and Control, 27, 7, pp. 604-620, (2016); Pandey H., Garg D., Luthra S., Identification and ranking of enablers of green Lean Six Sigma implementation using AHP, International Journal of Productivity and Quality Management, 23, 2, pp. 187-217, (2018); Pepper M.P.J., Spedding T.A., The evolution of Lean Six Sigma, International Journal of Quality & Reliability Management, 27, 2, pp. 138-155, (2010); Salah S., Rahim A., Carretero J.A., The integration of Six Sigma and lean management, International Journal of Lean Six Sigma, 1, 3, pp. 249-274, (2010); Samadhiya A., Achieving sustainability through holistic maintenance-key for competitiveness, Proceedings of the International Conference on Industrial Engineering and Operations Management, pp. 400-408, (2020); Sony M., Naik S., Green Lean Six Sigma implementation framework: a case of reducing graphite and dust pollution, International Journal of Sustainable Engineering, 13, 3, pp. 184-193, (2019); Sreedharan V.R., Sandhya G., Raju R., Development of a green Lean Six Sigma model for public sectors, International Journal of Lean Six Sigma, 9, 2, pp. 238-255, (2018)","A. Ibrahim; Department of Mechanical Engineering, BITS Pilani, Dubai Campus, Dubai, United Arab Emirates; email: p20200003@dubai.bits-pilani.ac.in","","Inderscience Publishers","","","","","","14792494","","","","English","Int. J. Six Sigma Compet. Advantage","Article","Final","","Scopus","2-s2.0-85175322333" -"Yuvaraja N.; Perumandla S.","Yuvaraja, N. (58606314000); Perumandla, Swamy (57204040519)","58606314000; 57204040519","A bibliometric evaluation of financial literacy and investment: a three-decade study based on the Scopus database, current research trends, and future directions","2024","International Journal of Process Management and Benchmarking","17","1","","89","108","19","2","10.1504/IJPMB.2024.137788","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85190451504&doi=10.1504%2fIJPMB.2024.137788&partnerID=40&md5=fc9100162e5a767a99b29de48aa23ad1","VIT Business School, Vellore Institute of Technology, Tamil Nadu, Vellore, India","Yuvaraja N., VIT Business School, Vellore Institute of Technology, Tamil Nadu, Vellore, India; Perumandla S., VIT Business School, Vellore Institute of Technology, Tamil Nadu, Vellore, India","Financial literacy is a key predictor of investment. However, a thorough scientific mapping of financial literacy and investment has not been attempted before. Therefore, in this study, we performed bibliometric analysis using VOS Viewer (van Eck and Waltman, 2010) and an R-language programme called bibliometrix (Aria and Cuccurullo, 2017) to dissect the intellectual and conceptual framework of the literature in this domain. Our findings indicated that the topic has intrigued scholars for the last 15 years, probably because of issues like global financial crisis and COVID-19. Gradually, this field became multidisciplinary, covering areas such as psychology, public economics, etc. The research themes, current trends, and potential areas of future research were highlighted. Our study will help policymakers understand the existing literature in this domain and help them plan their work accordingly. This study will help researchers identify future research opportunities on this topic by understanding influential papers, authors, and journals. Copyright © 2024 Inderscience Enterprises Ltd.","behavioural finance; bibliometric analysis; financial education; financial knowledge; financial literacy; future directions; investment; science mapping; stock market participation","","","","","","","","Acharya V.V., Richardson M., Restoring Financial Stability How to Repair a Failed System, (2009); Adil M., Singh Y., Ansari M.S., How financial literacy moderate the association between behaviour biases and investment decision?, Asian Journal of Accounting Research, 7, 1, pp. 17-30, (2022); Agarwalla S.K., Barua S.K., Jacob J., Varma J.R., Financial literacy among working young in urban India, World Development, 67, 1, pp. 101-109, (2015); Ahmed R., Does financial behavior influence financial well-being?, Journal of Asian Finance, Economics and Business, 8, 2, pp. 273-280, (2021); Akhtar F., Das N., Predictors of investment intention in Indian Stock Markets, International Journal of Bank Marketing, 37, 1, pp. 97-119, (2019); Alaaraj H., Bakri A., The effect of financial literacy on investment decision making in Southern Lebanon, International Business and Accounting Research Journal, 4, 1, (2020); Ali R., Rehman R.U., Suleman S., Ntim C.G., CEO attributes, investment decisions, and firm performance: new insights from upper echelons theory, Managerial and Decision Economics, 43, 2, pp. 398-417, (2022); Allgood S., Walstad W.B., The effects of perceived and actual financial literacy on financial behaviors, Economic Inquiry, 54, 1, pp. 675-697, (2016); Almenberg J., Dreber A., Gender, stock market participation and Financial Literacy, Economics Letters, 137, 1, pp. 140-142, (2015); Al-Tamimi H.A.H., Kalli A.B., Financial literacy and investment decisions of UAE investors, Journal of Risk Finance, 10, 5, pp. 500-516, (2009); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Babajide A., Osabuohien E., Tunji-Olayeni P., Falola H., Amodu L., Olokoyo F., Adegboye F., Ehikioya B., Financial literacy, financial capabilities, and sustainable business model practice among small business owners in Nigeria, Journal of Sustainable Finance and Investment, 11, 1, pp. 1-26, (2021); Bai Z., Does robo-advisory help reduce the likelihood of carrying a credit card debt? evidence from an instrumental variable approach, Journal of Behavioral and Experimental Finance, 29, 1, (2021); Bazley W.J., Bonaparte Y., Korniotis G.M., Financial self-awareness: who knows what they don’t know?, Finance Research Letters, 38, 1, (2021); Becchetti L., Caiazza S., Coviello D., Financial education and investment attitudes in high schools: evidence from a randomized experiment, Applied Financial Economics, 23, 10, pp. 817-836, (2013); Bernardo C.D., Lagoa S.C., Leao E.R., Determinants of bank customers’ demand for liquidity: the effect of bank capital and customers’ characteristics, International Journal of Monetary Economics and Finance, 8, 3, pp. 242-264, (2015); Bucher-Koenen T., Ziegelmeyer M., Once burned, twice shy? 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T., Promotion and prevention across mental accounts: when financial products dictate consumers and investment goals, Journal of Consumer Research, 31, 1, pp. 125-135, (2004); Zou J., Deng X., Financial literacy, housing value and household financial market participation: evidence from urban China, China Economic Review, 55, 1, pp. 52-66, (2019)","S. Perumandla; VIT Business School, Vellore Institute of Technology, Vellore, Tamil Nadu, India; email: swamy.perumandla@vit.ac.in","","Inderscience Publishers","","","","","","14606739","","","","English","Int. J. Process Manage. Benchmarking","Article","Final","","Scopus","2-s2.0-85190451504" -"Dewamuni Z.; Shanmugam B.; Azam S.; Thennadil S.","Dewamuni, Zenith (58772103200); Shanmugam, Bharanidharan (20436394800); Azam, Sami (54894635100); Thennadil, Suresh (9036564300)","58772103200; 20436394800; 54894635100; 9036564300","Bibliometric Analysis of IoT Lightweight Cryptography","2023","Information (Switzerland)","14","12","635","","","","8","10.3390/info14120635","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180193065&doi=10.3390%2finfo14120635&partnerID=40&md5=d01c3b3f16008661572fa9b4e60e69e8","Energy and Resources Institute, Faculty of Science and Technology, Charles Darwin University, Darwin, 0810, Australia","Dewamuni Z., Energy and Resources Institute, Faculty of Science and Technology, Charles Darwin University, Darwin, 0810, Australia; Shanmugam B., Energy and Resources Institute, Faculty of Science and Technology, Charles Darwin University, Darwin, 0810, Australia; Azam S., Energy and Resources Institute, Faculty of Science and Technology, Charles Darwin University, Darwin, 0810, Australia; Thennadil S., Energy and Resources Institute, Faculty of Science and Technology, Charles Darwin University, Darwin, 0810, Australia","In the rapidly developing world of the Internet of Things (IoT), data security has become increasingly important since massive personal data are collected. IoT devices have resource constraints, which makes traditional cryptographic algorithms ineffective for securing IoT devices. To overcome resource limitations, lightweight cryptographic algorithms are needed. To identify research trends and patterns in IoT security, it is crucial to analyze existing works, keywords, authors, journals, and citations. We conducted a bibliometric analysis using performance mapping, science mapping, and enrichment techniques to collect the necessary information. Our analysis included 979 Scopus articles, 214 WOS articles, and 144 IEEE Xplore articles published during 2015–2023, and duplicates were removed. We analyzed and visualized the bibliometric data using R version 4.3.1, VOSviewer version 1.6.19, and the bibliometrix library. We discovered that India is the leading country for this type of research. Archarya and Bansod are the most relevant authors; lightweight cryptography and cryptography are the most relevant terms; and IEEE Access is the most significant journal. Research on lightweight cryptographic algorithms for IoT devices (Raspberry Pi) has been identified as an important area for future research. © 2023 by the authors.","bibliometric analysis; IoT security; lightweight cipher algorithm","Cryptography; Developing countries; Mapping; Bibliometrics analysis; Cipher algorithms; Cryptographic algorithms; Developing world; Internet of thing security; Light-weight cryptography; Lightweight cipher algorithm; Lightweight ciphers; Resource Constraint; Resource limitations; Internet of things","","","","","","","Tiwary A., Mahato M., Chidar A., Chandrol M.K., Shrivastava M., Tripathi M., Internet of Things (IoT): Research, Architectures, and Applications, Int. J. Future Rev. Comput. Sci. Commun. 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Shanmugam; Energy and Resources Institute, Faculty of Science and Technology, Charles Darwin University, Darwin, 0810, Australia; email: bharanidharan.shanmugam@cdu.edu.au","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20782489","","","","English","Information","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85180193065" -"Kumar S.; Pandey N.; Burton B.; Sureka R.","Kumar, Satish (57992552600); Pandey, Nitesh (57211577722); Burton, Bruce (36878314900); Sureka, Riya (57211688395)","57992552600; 57211577722; 36878314900; 57211688395","Research patterns and intellectual structure of Managerial Auditing Journal: a retrospective using bibliometric analysis during 1986-2019","2021","Managerial Auditing Journal","36","2","","280","313","33","29","10.1108/MAJ-12-2019-2517","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101080368&doi=10.1108%2fMAJ-12-2019-2517&partnerID=40&md5=4c7018298e84f4890e3610529377f321","Department of Management Studies, Malaviya National Institute of Technology, Jaipur, India; School of Business, University of Dundee, Dundee, United Kingdom","Kumar S., Department of Management Studies, Malaviya National Institute of Technology, Jaipur, India; Pandey N., Department of Management Studies, Malaviya National Institute of Technology, Jaipur, India; Burton B., School of Business, University of Dundee, Dundee, United Kingdom; Sureka R., Department of Management Studies, Malaviya National Institute of Technology, Jaipur, India","Purpose: The Managerial Auditing Journal (MAJ) started publication in 1986 and celebrates its 35th year of publication in 2020. The purpose of this study is to provide a detailed bibliometric analysis of the journal’s primary trends and themes between 1986 and 2019. Design/methodology/approach: This study uses the Scopus database to analyse the most prolific authors in the MAJ along with their affiliated institutions and countries; the work also identifies the MAJ articles cited most often by other journals. A range of bibliometric devices is applied to analyse the publication and citation structure of MAJ, alongside performance analysis and science mapping tools. The study also provides a detailed inter-temporal analysis of MAJ publishing patterns. Findings: The MAJ publishes around 40 articles each year with citations of this work steadily growing over time. The journal has attracted contributors from around the globe, most often affiliated with the USA, the UK and Australia. Thematic evolution of the journal’s themes reveals that it has expanded its scope to include topics such as internal auditing, internal control and corporate governance, whilst co-authorship analysis reveals that the journal’s collaboration network has grown to span the globe. Research limitations/implications: As this study uses data from the Scopus database, any shortcomings therein will be reflected in the study. Originality/value: This study provides the first overview of the MAJ’s publication and citation trends as well as the evolution of its thematic structure. It also suggests future directions that the journal might take. © 2021, Emerald Publishing Limited.","Bibliometrix; Citation analysis; Gephi; h-index; Keywords analysis; Managerial Auditing Journal; Scopus; VOSviewer","","","","","","","","Acedo F.J., Barroso C., Casanueva C., Galan J.L., Co-Authorship in management and organizational studies: an empirical and network analysis, Journal of Management Studies, 43, 5, pp. 957-983, (2006); Alonso S., Cabrerizo F.J., Herrera-Viedma E., Herrera F., h-Index: a review focused in its variants, computation and standardization for different scientific fields, Journal of Informetrics, 3, 4, pp. 273-289, (2009); Amran A., Manaf Rosli Bin A., Che Haat Mohd Hassan B., Risk reporting: an exploratory study on risk management disclosure in Malaysian annual reports, Managerial Auditing Journal, 24, 1, pp. 39-57, (2009); Andrikopoulos A., Trichas G., Publication patterns and coauthorship in the journal of corporate finance, Journal of Corporate Finance, 51, pp. 98-108, (2018); Antony J., Six sigma in the UK service organisations: Results from a pilot survey, Managerial Auditing Journal, 19, 8, pp. 1006-1013, (2004); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Baker H.K., Kumar S., Pandey N., Thirty years of the global finance journal: a bibliometric analysis, Global Finance Journal, (2019); Baker H.K., Kumar S., Pandey N., Thirty years of small business economics: a bibliometric overview, Small Business Economics, pp. 1-31, (2020); Baker H.K., Kumar S., Pandey N., A bibliometric analysis of managerial finance: a retrospective, Managerial Finance, 46, 11, (2020); Baker H.K., Kumar S., Pattnaik D., Twenty-five years of the journal of corporate finance: a scientometric analysis journal of corporate finance, (2020); Bastian M., Heymann S., Jacomy M., Gephi: an open source software for exploring and manipulating networks, Proceedings of the Third International ICWSM Conference (2009), pp. 361-362, (2009); Burton B., Kumar S., Pandey N., Twenty-five years of the European journal of finance (EJF): a retrospective analysis, The European Journal of Finance, 26, 18, (2020); Callon M., Courtial J.P., Laville F., Co-word analysis as a tool for describing the network of interactions between basic and technological research—the case of polymer chemistry, Scientometrics, 22, 1, pp. 155-205, (1991); Chan S.Y.S., Leung P., The effects of accounting students’ ethical reasoning and personal factors on their ethical sensitivity, Managerial Auditing Journal, 21, 4, pp. 436-457, (2006); Cisneros L., Ibanescu M., Keen C., Lobato-Calleros O., Niebla-Zatarain J., Bibliometric study of family business succession between 1939 and 2017: mapping and analyzing authors’ networks, Scientometrics, 117, 2, pp. 919-951, (2018); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: a practical application to the fuzzy sets theory field, Journal of Informetrics, 5, 1, pp. 146-166, (2011); Conlon D.E., Morgeson F.P., McNamara G., Wiseman R.M., Skilton P.F., Examining the impact and role of special issue and regular journal articles in the field of management, Academy of Management Journal, 49, 5, pp. 857-872, (2006); Coulter N., Monarch I., Konda S., Software engineering as seen through its research literature: a study in co‐word analysis, Journal of the American Society for Information Science, 49, 13, pp. 1206-1223, (1998); Coyne J.G., Summers S.L., Williams B., Wood D.A., Accounting program research rankings by topical area and methodology, Issues in Accounting Education, 25, 4, pp. 631-654, (2010); Crane D., Social structure in a group of scientists: a test of the “ invisible college, American Sociological Review, 34, 3, pp. 335-352, (1969); Emich K.J., Kumar S., Lu L., Norder K., Pandey N., Mapping 50 years of small group research through small group research, Small Group Research, 51, 6, pp. 659-699, (2020); Fadzil F.H., Haron H., Jantan M., Internal auditing practices and internal control system, Managerial Auditing Journal, 20, 8, pp. 844-866, (2005); Ferramosca S., Verona R., Framing the evolution of corporate social responsibility as a discipline (1973–2018): a large-scale scientometric analysis, Corporate Social Responsibility and Environmental Management, 27, 1, pp. 178-203, (2020); Fogarty T.J., Jonas G.A., Author characteristics for major accounting journals: Differences among similarities 1989–2009, Issues in Accounting Education, 28, 4, pp. 731-757, (2013); Gaviria-Marin M., Merigo J.M., Popa S., Twenty years of the journal of knowledge management: a bibliometric analysis, Journal of Knowledge Management, 22, 8, pp. 1655-1687, (2018); Goodwin-Stewart J., Kent P., The use of internal audit by Australian companies, Managerial Auditing Journal, 21, 1, pp. 81-101, (2006); Guffey D.M., Harp N.L., Ranking faculties, Ph.D. programs, individual scholars, and influential articles in accounting information systems based on citations to publications in the journal of information systems, Journal of Information Systems, 28, 1, pp. 111-144, (2014); Haat M.H.C., Rahman R.A., Mahenthiran S., Corporate governance, transparency and performance of Malaysian companies, Managerial Auditing Journal, 23, 8, (2008); Hassan M.K., The development of accounting regulations in Egypt: Legitimating the international accounting standards, Managerial Auditing Journal, 23, 5, pp. 467-484, (2008); Heck J.L., Bremser W.G., Six decades of the accounting review: a summary of author and institutional contributors, The Accounting Review, 61, 4, pp. 735-744, (1986); Henderson M., Shurville S., Fernstrom K., The quantitative crunch: the impact of bibliometric research quality assessment exercises on academic development at small conferences, Campus-Wide Information Systems, 26, 3, pp. 149-167, (2009); Huafang X., Jianguo Y., Ownership structure, board composition and corporate voluntary disclosure: Evidence from listed companies in China, Managerial Auditing Journal, 22, 6, pp. 604-619, (2007); Jackling B., Cooper B.J., Leung P., Dellaportas S., Professional accounting bodies’ perceptions of ethical issues, causes of ethical failure and ethics education, Managerial Auditing Journal, 22, 9, pp. 928-944, (2007); Jarrar Y.F., Knowledge management: learning for organisational experience, Managerial Auditing Journal, 17, 6, pp. 322-328, (2002); Khlif H., Samaha K., Audit committee activity and internal control quality in Egypt: Does external auditor’s size matter?, Managerial Auditing Journal, 31, 3, pp. 269-289, (2016); Krishnan G.V., Yu W., Further evidence on knowledge spillover and the joint determination of audit and non-audit fees, Managerial Auditing Journal, 26, 3, pp. 230-247, (2011); KumarSureka S., Pandey N., A retrospective overview of the Asian review of accounting during 1992–2019, (2020); Kung F.H., Chang Y.S., Zhou M., The effect of gender composition in joint audits on earnings management, Managerial Auditing Journal, 34, 5, pp. 545-570, (2019); Lin J.W., Hwang M.I., Becker J.D., A fuzzy neural network for assessing the risk of fraudulent financial reporting, Managerial Auditing Journal, 18, 8, pp. 657-665, (2003); Lindquist T.M., Smith G., Journal of management accounting research: Content and citation analysis of the first 20 years, Journal of Management Accounting Research, 21, 1, pp. 249-292, (2009); 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A retrospective evaluation (1974-1991), Journal of Financial Economics, 33, 3, pp. 369-424, (1993); Shapeero M., Chye Koh H., Killough L.N., Underreporting and premature sign‐off in public accounting, Managerial Auditing Journal, 18, 6-7, pp. 478-489, (2003); Soh D.S.B., Martinov-Bennie N., The internal audit function: Perceptions of internal audit roles, effectiveness and evaluation, Managerial Auditing Journal, 26, 7, pp. 605-622, (2011); Sulaiman M.B., Nazli Nik Ahmad N., Alwi N., Management accounting practices in selected Asian countries: a review of the literature, Managerial Auditing Journal, 19, 4, pp. 493-508, (2004); Uysal O.O., Business ethics research with an accounting focus: a bibliometric analysis from 1988 to 2007, Journal of Business Ethics, 93, 1, pp. 137-160, (2010); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Vasarhelyi M.A., Bao D.H., Berk J., Trends in the evolution of scholarly accounting thought: a quantitative examination, Accounting Historians Journal, 15, 1, pp. 45-64, (1988); Yang D.C., Guan L., The evolution of IT auditing and internal control standards in financial statement audits: the case of the United States, Managerial Auditing Journal, 19, 4, pp. 544-555, (2004)","S. Kumar; Department of Management Studies, Malaviya National Institute of Technology, Jaipur, India; email: skumar.dms@mnit.ac.in","","Emerald Group Holdings Ltd.","","","","","","02686902","","","","English","Manage. Audit. J.","Article","Final","All Open Access; Green Open Access","Scopus","2-s2.0-85101080368" -"Linnenluecke M.K.; Marrone M.; Singh A.K.","Linnenluecke, Martina K (34768782000); Marrone, Mauricio (36135658300); Singh, Abhay K (55726472500)","34768782000; 36135658300; 55726472500","Conducting systematic literature reviews and bibliometric analyses","2020","Australian Journal of Management","45","2","","175","194","19","969","10.1177/0312896219877678","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074036323&doi=10.1177%2f0312896219877678&partnerID=40&md5=c48b20874ffeeb40cd63ed2c49886e91","Centre for Corporate Sustainability and Environmental Finance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia; Department of Accounting and Corporate Governance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia; Department of Applied Finance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia","Linnenluecke M.K., Centre for Corporate Sustainability and Environmental Finance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia; Marrone M., Department of Accounting and Corporate Governance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia; Singh A.K., Department of Applied Finance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia","Literature reviews play an essential role in academic research to gather existing knowledge and to examine the state of a field. However, researchers in business, management and related disciplines continue to rely on cursory and narrative reviews that lack a systematic investigation of the literature. This article details methodological steps for conducting literature reviews in a replicable and scientific fashion. This article also discusses bibliographic mapping approaches to visualise bibliometric information and findings from a systematic literature review. We hope that the insights provided in this article are useful for researchers at different stages of their careers – ranging from doctoral students who wish to assemble a broad overview of their field of interest to guide their work, to senior researchers who wish to publish authoritative literature reviews. JEL Classification: C18, C80, C88, M10, M20. © The Author(s) 2019.","Bibliographic mapping; citation graph; entity linking; HistCite; R. Bibliometrix; ResGap; science mapping; systematic literature review; text mining","","","","","","Australian Research Council, ARC, (DP160103425); Australian Research Council, ARC"," https://orcid.org/0000-0001-7984-9717 Linnenluecke Martina K Centre for Corporate Sustainability and Environmental Finance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia Marrone Mauricio Department of Accounting and Corporate Governance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia Singh Abhay K Department of Applied Finance, Macquarie Business School, Macquarie University, Sydney, NSW, Australia Martina K Linnenluecke, Centre for Corporate Sustainability and Environmental Finance, Macquarie Business School, Macquarie University, Eastern Road, Sydney, NSW 2109, Australia. Email: martina.linnenluecke@mq.edu.au 10 2019 0312896219877678 © The Author(s) 2019 2019 The University of New South Wales Literature reviews play an essential role in academic research to gather existing knowledge and to examine the state of a field. However, researchers in business, management and related disciplines continue to rely on cursory and narrative reviews that lack a systematic investigation of the literature. This article details methodological steps for conducting literature reviews in a replicable and scientific fashion. This article also discusses bibliographic mapping approaches to visualise bibliometric information and findings from a systematic literature review. We hope that the insights provided in this article are useful for researchers at different stages of their careers – ranging from doctoral students who wish to assemble a broad overview of their field of interest to guide their work, to senior researchers who wish to publish authoritative literature reviews. JEL Classification: C18, C80, C88, M10, M20 Bibliographic mapping citation graph entity linking HistCite R. Bibliometrix ResGap science mapping systematic literature review text mining Australian Research Council https://doi.org/10.13039/501100000923 DP160103425 edited-state corrected-proof Final transcript accepted 31 August 2019 by Jane Baxter (Editor in Chief). Funding The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: The first author (M.K.L.) acknowledges funding by the Australian Research Council (DP160103425). ORCID iD Martina K Linnenluecke https://orcid.org/0000-0001-7984-9717 ","Adams R.J., Smart P., Huff A.S., Shades of grey: Guidelines for working with the grey literature in systematic reviews for management and organizational studies, International Journal of Management Reviews, 19, pp. 432-454, (2017); Addor N., Melsen L., Legacy, rather than adequacy, drives the selection of hydrological models, Water Resources Research, 55, pp. 378-390, (2019); Akobeng A.K., Understanding systematic reviews and meta-analysis, Archives of Disease in Childhood, 90, pp. 845-848, (2005); Aria M., Cuccurullo C., bibliometrix: An R tool for comprehensive science mapping analysis, Journal of Informetrics, 11, pp. 959-975, (2017); Bailey C., Madden A., Alfes K., Et al., The meaning, antecedents and outcomes of employee engagement: A narrative synthesis, International Journal of Management Reviews, 19, pp. 31-53, (2017); Batra S., Sharma S., Dixit M.R., Et al., Does strategic planning determine innovation in organizations? 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Linnenluecke M.K., Chen X., Ling X., Et al., Research in finance: A review of influential publications and a research agenda, Pacific-Basin Finance Journal, 43, pp. 188-199, (2017); Linnenluecke M.K., Meath C., Rekker S., Et al., Divestment from fossil fuel companies: Confluence between policy and strategic viewpoints, Australian Journal of Management, 40, pp. 478-487, (2015); Liu X., Jiang T., Ma F., Collective dynamics in knowledge networks: Emerging trends analysis, Journal of Informetrics, 7, pp. 425-438, (2013); Marrone M., Hammerle M., Relevant research areas in IT service management: An examination of academic and practitioner literatures, Communications of the Association for Information Systems, 41, pp. 517-543, (2017); Martineau A.R., Jolliffe D.A., Hooper R.L., Et al., Vitamin D supplementation to prevent acute respiratory tract infections: Systematic review and meta-analysis of individual participant data, The BMJ, 356, (2017); Moher D., Liberati A., Tetzlaff J., Et al., Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement, Annals of Internal Medicine, 151, pp. 264-269, (2009); Mulrow C.D., Systematic reviews: Rationale for systematic reviews, The BMJ, 309, pp. 597-599, (1994); Nederhof A., Van Wijk E., Mapping the social and behavioral sciences world-wide: Use of maps in portfolio analysis of national research efforts, Scientometrics, 40, pp. 237-276, (1997); R: A Language and Environment for Statistical Computing, (2019); Rstudio: Integrated Development Environment for R, (2019); Sternberg R.J., Editorial, Psychological Bulletin, 109, pp. 3-4, (1991); Sutton R.I., Staw B.M., What theory is not, Administrative Science Quarterly, pp. 371-384, (1995); Tranfield D., Denyer D., Smart P., Towards a methodology for developing evidence-informed management knowledge by means of systematic review, British Journal of Management, 14, pp. 207-222, (2003); Tweedie D., Wild D., Rhodes C., Et al., How does performance management affect workers? Beyond human resource management and its critique, International Journal of Management Reviews, 21, pp. 76-96, (2019); Webster J., Watson R.T., Analyzing the past to prepare for the future: Writing a literature review, MIS Quarterly, 26, (2002); Westgate M.J., Revtools: Bibliographic data visualization for evidence synthesis in R, bioRxiv, (2018); Westgate M.J., Barton P.S., Pierson J.C., Et al., Text analysis tools for identification of emerging topics and research gaps in conservation science, Conservation Biology, 29, pp. 1606-1614, (2015)","M.K. Linnenluecke; Centre for Corporate Sustainability and Environmental Finance, Macquarie Business School, Macquarie University, Sydney, Australia; email: martina.linnenluecke@mq.edu.au","","SAGE Publications Ltd","","","","","","03128962","","","","English","Aust. J. Manage.","Review","Final","","Scopus","2-s2.0-85074036323" -"Kurniasih N.; Kuswarno E.; Yanto A.; Suganda T.","Kurniasih, Nuning (57200989264); Kuswarno, Engkus (57192938361); Yanto, Andri (57200989106); Suganda, Tarkus (57218955264)","57200989264; 57192938361; 57200989106; 57218955264","Science mapping for popular topics in cyberbullying prevention articles","2020","Library Philosophy and Practice","2020","","4101","","","","2","","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090884896&partnerID=40&md5=6274b9405e091302c2df116b7e115b1d","Faculty of Communication Sciences, Universitas Padjadjaran, Bandung, Indonesia; Faculty of Agriculture, Universitas Padjadjaran, Bandung, Indonesia","Kurniasih N., Faculty of Communication Sciences, Universitas Padjadjaran, Bandung, Indonesia; Kuswarno E., Faculty of Communication Sciences, Universitas Padjadjaran, Bandung, Indonesia; Yanto A., Faculty of Communication Sciences, Universitas Padjadjaran, Bandung, Indonesia; Suganda T., Faculty of Agriculture, Universitas Padjadjaran, Bandung, Indonesia","An increase in cyberbullying has been shown by various survey results. This condition raises the attention and awareness of global society towards cyberbullying. The awareness of the global community in dealing with cyberbullying generates particular thoughts and programs or anti-cyberbullying movements. In this case, this article aims to analyze the popular topics in the documents related to cyberbullying prevention. The analysis is conducted through science mapping using the Biblioshiny for Bibliometrix from the R Tool. Furthermore, 713 documents are obtained after searched through the keywords: protection OR prevention OR against AND cyberbullying, on the Scopus Database on March 17th, 2020. The analysis reveals that 713 documents about cyberbullying prevention are commenced in 2006. The ""Computer in Human Behavior"" journal is selected as the most relevant source based on the number of documents for this theme. The word 'adolescent', especially female adolescents, is mentioned more in the documents related to cyberbullying prevention. This can indicate that cyberbullying more commonly happens among adolescents, especially female adolescents. Moreover, the topic dendrogram shows that the theme of cyberbullying in social networking is served as a separate theme. Other popular themes are produced at least through 3 approaches, that are survey, experimental (controlled study) and psychological/psychiatric approaches. It is expected that being familiar with the research topics in cyberbullying can contribute a comprehension for related parties towards the developing issues so that cyberbullying prevention programs can be effectively created. © 2020, University of Idaho Library.","Biblioshiny; Cyberbullying prevention; R tool; Science mapping; Topics in cyberbullying","","","","","","Universitas Padjadjaran","This article is part of the output for the Community Service activities supported by the Universitas Padjadjaran Internal Grant in 2020.","Anderson M., Pew Research Center, September 2018, ""A Majority of Teens Have Experienced Some Form of Cyberbullying."", (2018); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bhat C.S., Chang S.H., Linscott J.A., Addressing cyberbullying as a media literacy issue, New Horizons in Education, 58, 3, (2010); Chen C., Dubin R., Schultz T., Science mapping, Encyclopedia of Information Science and Technology, Third Edition, pp. 4171-4184, (2014); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Hinduja S., Patchin J.W., Cyberbullying: Identification,Prevention and Response, cyberbullying Research Center, (2014); Cyber Bullying: Statistics and Tips, (2009); Johnson L.D., Haralson A., Batts S., Brown E., Collins C., Van Buren-Travis A., Spencer M., Cyberbullying on Social Media Among College Students, Vistas Online, (2016); Kurniasih N., Kuswarno E., Yanto A., Sugiana D., Media Literacy to Overcome Cyberbullying: Case Study in an Elementary School in Bandung Indonesia, Library Philosophy and Practice (e-Journal), (2020); Leydesdorff L., Various methods for the mapping of science, Scientometrics: An International Journal for All Quantitative Aspects of the Science of Science, Communication in Science and Science Policy, 11, 5, pp. 295-324, (1987); Lindfors P.L., Kaltiala-Heino R., Rimpela A.H., Cyberbullying among Finnish adolescents - A population-based study, BMC Public Health, 12, 1, pp. 1-5, (2012); Moral-Munoz J.A., Herrera-Viedma E., Santisteban-Espejo A., Cobo M.J., Software tools for conducting bibliometric analysis in science: An up-to-date review, El Profesional de La Información, 29, 1, pp. 1-20, (2020); Morris S.A., Van Der Veer Martens B., Mapping research specialties, Association for Information Science & Technology, 42, 1, pp. 213-295, (2009); Newall M., Cyberbullying: A global advisor survey, pp. 1-12, (2018); Noyons E.C.M., Buter R.K., Van Raan A.F.J., Bibliometric mapping as a science policy tool, Proceedings of the International Conference on Information Visualisation, 2002-Janua, pp. 679-684, (2002); Noyons E.C.M., Moed H.F., Van Raan A.F.J., Integrating research performance analysis and science mapping, Scientometrics, 46, 3, pp. 591-604, (1999); O'Dea B., Campbell A., Online social networking and the experience of cyber-bullying, Annual Review of CyberTherapy and Telemedicine, 10, pp. 212-217, (2012); Peng R.D., R Programming for Data Science, The R Project; R Foundation, (2015); Smith P.K., Bullying: Definition, Types, Causes, Consequences and Intervention, Social and Personality Psychology Compass, 10, 9, pp. 519-532, (2016); Van Hee C., Jacobs G., Emmery C., DeSmet B., Lefever E., Verhoeven B., Hoste V., Automatic detection of cyberbullying in social media text, PLoS ONE, 13, 10, pp. 1-22, (2018)","N. Kurniasih; Faculty of Communication Sciences, Universitas Padjadjaran, Bandung, Indonesia; email: nuning.kurniasih@unpad.ac.id","","University of Idaho Library","","","","","","15220222","","","","English","Libr. Philos. Pract.","Article","Final","","Scopus","2-s2.0-85090884896" -"Oluwadele D.; Singh Y.; Adeliyi T.T.","Oluwadele, Deborah (57816350100); Singh, Yashik (36613671100); Adeliyi, Timothy T. (57203191431)","57816350100; 36613671100; 57203191431","E-Learning Performance Evaluation in Medical Education—A Bibliometric and Visualization Analysis","2023","Healthcare (Switzerland)","11","2","232","","","","6","10.3390/healthcare11020232","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146816474&doi=10.3390%2fhealthcare11020232&partnerID=40&md5=2a38fd2e318929eb66062df94664166b","Department of Telemedicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, 4041, South Africa; ICT and Society Research Group, Information Technology, Durban University of Technology, Durban, 4001, South Africa","Oluwadele D., Department of Telemedicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, 4041, South Africa; Singh Y., Department of Telemedicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, 4041, South Africa; Adeliyi T.T., ICT and Society Research Group, Information Technology, Durban University of Technology, Durban, 4001, South Africa","Performance evaluation is one of the most critical components in assuring the comprehensive development of e-learning in medical education (e-LMED). Although several studies evaluate performance in e-LMED, no study presently maps the rising scientific knowledge and evolutionary patterns that establish a solid background to investigate and quantify the efficacy of the evaluation of performance in e-LMED. Therefore, this study aims to quantify scientific productivity, identify the key terms and analyze the extent of research collaboration in this domain. We searched the SCOPUS database using search terms informed by the PICOS model, and a total of 315 studies published between 1991 and 2022 were retrieved. Performance analysis, science mapping, network analysis, and visualization were performed using R Bibliometrix, Biblioshiny, and VOSviewer packages. Findings reveal that authors are actively publishing and collaborating in this domain, which experienced a sporadic publication increase in 2021. Most of the top publications, collaborations, countries, institutions, and journals are produced in first-world countries. In addition, studies evaluating performance in e-LMED evaluated constructs such as efficacy, knowledge gain, student perception, confidence level, acceptability, feasibility, usability, and willingness to recommend e-learning, mainly using pre-tests and post-tests experimental design methods. This study can help researchers understand the existing landscape of performance evaluation in e-LMED and could be used as a background to investigate and quantify the efficacy of the evaluation of e-LMED. © 2023 by the authors.","bibliometric analysis; e-learning; medical education; performance evaluation","","","","","","","","Weeden K.A., Small M., The Small-World Network of College Classes: Implications for Epidemic Spread on a University Campus, Sociol. 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Teknoinfo, 16, (2022); Abedi F., Lari S.M., Afshari R., Tarazkhaki S.N., Karimoi M.N., Talebi M., Evaluation of E-learning System to the Performance of Family Medicine MPH (Master of Public Health) Students, Future Med. Educ. J, 5, pp. 38-41, (2015); Borakati A., Evaluation of an international medical E-learning course with natural language processing and machine learning, BMC Med. Educ, 21, (2021); Kalfsvel L., Versmissen J., Doorn A., Broek W., Kuy H., Rosse F., Better performance of medical students on pharmacotherapy knowledge and skills tests is associated with practising with e-learning program P-scribe, Br. J. Clin. Pharmacol, 88, pp. 1334-1346, (2022); Stevens N.T., Holmes K., Grainger R.J., Connolly R., Prior A.R., Fitzpatrick F., O'Neill E., Boland F., Pawlikowska T., Humphreys H., Can e-learning improve the performance of undergraduate medical students in Clinical Microbiology examinations?, BMC Med. Educ, 19, (2019); Tashkandi E., E-Learning for Undergraduate Medical Students, Adv. Med. Educ. Pract, 12, pp. 665-674, (2021); De Leeuw R., De Soet A., Van Der Horst S., Walsh K., Westerman M., Scheele F., How We Evaluate Postgraduate Medical E-Learning: Systematic Review, JMIR Med. Educ, 5, (2019); Sears K.E., Cohen J.E., Drope J., Comprehensive evaluation of an online tobacco control continuing education course in Canada, J. Contin. Educ. Health Prof, 28, pp. 235-240, (2008); Boye S., Moen T., Vik T., An e-learning course in medical immunology: Does it improve learning outcome?, Med. Teach, 34, pp. e649-e653, (2012); Bagayoko C.O., Perrin C., Gagnon M.-P., Geissbuhler A., Continuing Distance Education: A Capacity-Building Tool for the De-isolation of Care Professionals and Researchers, J. Gen. Intern. Med, 28, pp. 666-670, (2013); Donmus Kaya V., A Bibliometric Analysis of Using Web 2.0 s in Educational Research Area, Int. Online J. Educ. Teach, 9, pp. 194-216, (2022); Thurzo A., Stanko P., Urbanova W., Lysy J., Suchancova B., Makovnik M., Javorka V., The WEB 2.0 induced paradigm shift in the e-learning and the role of crowdsourcing in dental education, Bratisl. Lekárske Listy, 111, pp. 168-175, (2010); Nanda A., Hargest R., Douek M., Facemasks in the prevention of infection in surgery, Recent Advances in Surgery, 40, (2021); Clark R.C., Mayer R.E., Thalheimer W., E-Learning and the Science of Instruction: Proven Guidelines for Consumers and Designers of Multimedia Learning, (2016); Bravo E.R., Santana M., Rodon J., Information systems and performance: The role of technology, the task and the individual, Behav. Inf. Technol, 34, pp. 247-260, (2015); Ajenifuja D., Adeliyi T., Evaluating the Influence of E-Learning on the Performance of Healthcare Professionals in Providing Support, Int. J. E-Learn, 21, pp. 201-215, (2022); Oluwadele O.D., Assessing the Influence of E-Learning on the Performance of Healthcare Professionals: A Case Study of UKZN-NORHED Collaboration, Masters Thesis, (2017); Goodhue D.L., Understanding User Evaluations of Information Systems, Manag. Sci, 41, pp. 1827-1844, (1995); Kirkpatrick D., Great ideas revisited, Train. Dev, 50, pp. 54-59, (1996); Tautz D., Sprenger D.A., Schwaninger A., Evaluation of four digital tools and their perceived impact on active learning, repetition and feedback in a large university class, Comput. Educ, 175, (2021); Prasetyo Y.T., Ong A.K.S., Concepcion G.K.F., Navata F.M.B., Robles R.A.V., Tomagos I.J.T., Young M.N., Diaz J.F.T., Nadlifatin R., Redi A.A.N.P., Determining Factors Affecting Acceptance of E-Learning Platforms during the COVID-19 Pandemic: Integrating Extended Technology Acceptance Model and DeLone & McLean IS Success Model, Sustainability, 13, (2021); Li J., Construction of Modern Educational Technology MOOC Platform Based on Courseware Resource Storage System, Int. J. Emerg. Technol. Learn, 12, (2017); Fadhilah M.K., Surantha N., Isa S.M., Web-Based Evaluation System Using Kirkpatrick Model for High School Education (A Case Study for Vocational High School in Jakarta), Proceedings of the International Conference on Information Management and Technology (ICIMTech), pp. 166-171; Harrati N., Bouchrika I., Tari A., Ladjailia A., Exploring user satisfaction for e-learning systems via usage-based metrics and system usability scale analysis, Comput. Hum. Behav, 61, pp. 463-471, (2016); Pal D., Vanijja V., Perceived usability evaluation of Microsoft Teams as an online learning platform during COVID-19 using system usability scale and technology acceptance model in India, Child. Youth Serv. Rev, 119, (2020); Winarno D.A., Muslim E., Rafi M., Rosetta A., Quality Function Deployment Approach to Optimize E-learning Adoption among Lecturers in Universitas Indonesia, Proceedings of the 4th International Conference on Education and E-Learning; Scherer R., Siddiq F., Tondeur J., The technology acceptance model (TAM): A meta-analytic structural equation modeling approach to explaining teachers’ adoption of digital technology in education, Comput. Educ, 128, pp. 13-35, (2018); Priska M.A., Aulia D., Muslim E., Marcelina L., Developing a Framework to Evaluate E-Learning System at Higher Education in Indonesia, Proceedings of the 4th International Conference on Education and E-Learning; Rosetta A., Priska M.A., Muslim E., Rafi M., Evaluating the Success of E-Learning Systems and Strategy Creation: The Perspective of Students in Universitas Indonesia, Proceedings of the 4th International Conference on Education and E-Learning; Saaiq M., Ashraf B., Modifying “Pico” question into “Picos” model for more robust and reproducible presentation of the methodology employed in a scientific study, World J. Plast. Surg, 6, (2017); Kamien M., Macadam D., Grant J., Distance learning in a local setting: A structured learning course for the introduction of general practice to undergraduate students, Med. Teach, 13, pp. 353-361, (1991); Prigoff J., Hunter M., Nowygrod R., Medical Student Assessment in the Time of COVID-19, J. Surg. Educ, 78, pp. 370-374, (2021); Sekhar R., Sharma D., Shah P., State of the Art in Metal Matrix Composites Research: A Bibliometric Analysis, Appl. Syst. Innov, 4, (2021); Nagaraj C., Yadurappa S.B., Anantharaman L.T., Ravindranath Y., Shankar N., Effectiveness of blended learning in radiological anatomy for first year undergraduate medical students, Surg. Radiol. Anat, 43, pp. 489-496, (2021); Smith E., Boscak A., A virtual emergency: Learning lessons from remote medical student education during the COVID-19 pandemic, Emerg. Radiol, 28, pp. 445-452, (2021); Phillips A.L., Edwards S., Parmesar K., Soltan M., Guckian J., Slack as a virtual undergraduate dermatology community: A pilot study, Clin. Exp. Dermatol, 46, pp. 1028-1037, (2021); Matthews T., Tian F., Dolby T., Interaction design for paediatric emergency VR training, Virtual Real. Intell. Hardw, 2, pp. 330-344, (2020); Nilsson M., Ostergren J., Fors U., Rickenlund A., Jorfeldt L., Caidahl K., Bolinder G., Does individual learning styles influence the choice to use a web-based ECG learning programme in a blended learning setting?, BMC Med. Educ, 12, (2012); Klein K.P., Hannum W.M., Koroluk L.D., Proffit W.R., Interactive distance learning for orthodontic residents: Utilization and acceptability, Am. J. Orthod. Dentofac. Orthop, 141, pp. 378-385, (2012); Kulier R., Hadley J., Weinbrenner S., Meyerrose B., Decsi T., Horvath A.R., Nagy E., Emparanza J.I., Coppus S.F., Arvanitis T.N., Et al., Harmonising evidence-based medicine teaching: A study of the outcomes of e-learning in five European countries, BMC Med. Educ, 8, (2008); Garrett B.M., Jackson C., A mobile clinical e-portfolio for nursing and medical students, using wireless personal digital assistants (PDAs), Nurse Educ. Pract, 6, pp. 339-346, (2006); Jang K.S., Hwang S.Y., Park S.J., Kim Y.M., Kim M.J., Effects of a Web-Based Teaching Method on Undergraduate Nursing Students’ Learning of Electrocardiography, J. Nurs. Educ, 44, pp. 35-39, (2005); Levy K., Aghababian R.V., Hirsch E.F., Screnci D., Boshyan A., Ricks R.C., Samiei M., An Internet-based Exercise as a Component of an Overall Training Program Addressing Medical Aspects of Radiation Emergency Management, Prehospital Disaster Med, 15, pp. 18-25, (2000); Woltering V., Herrler A., Spitzer K., Spreckelsen C., Blended learning positively affects students’ satisfaction and the role of the tutor in the problem-based learning process: Results of a mixed-method evaluation, Adv. Health Sci. Educ, 14, pp. 725-738, (2009); Ellaway R., Poulton T., Fors U., McGee J.B., Albright S., Building a virtual patient commons, Med. Teach, 30, pp. 170-174, (2008); Childs S., Blenkinsopp E., Hall A., Walton G., Effective e-learning for health professionals and students—Barriers and their solutions. A systematic review of the literature—Findings from the HeXL project, Health Inf. Libr. J, 22, pp. 20-32, (2005); Curran V.R., Fleet L., A review of evaluation outcomes of web-based continuing medical education, Med. Educ, 39, pp. 561-567, (2005)","D. Oluwadele; Department of Telemedicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, 4041, South Africa; email: oluwadele.d@belgiumcampus.ac.za","","MDPI","","","","","","22279032","","","","English","Healthcare (Basel)","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85146816474" -"Shi K.; Zhou Y.; Zhang Z.","Shi, Kun (57224500889); Zhou, Yi (57224511987); Zhang, Zhen (58741904000)","57224500889; 57224511987; 58741904000","Mapping the research trends of household waste recycling: A bibliometric analysis","2021","Sustainability (Switzerland)","13","11","6029","","","","24","10.3390/su13116029","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107718734&doi=10.3390%2fsu13116029&partnerID=40&md5=79912d5d5dd98ff04d734002b3eafafa","Department of Environmental Science & Engineering, Fudan University, Shanghai, 200433, China","Shi K., Department of Environmental Science & Engineering, Fudan University, Shanghai, 200433, China; Zhou Y., Department of Environmental Science & Engineering, Fudan University, Shanghai, 200433, China; Zhang Z., Department of Environmental Science & Engineering, Fudan University, Shanghai, 200433, China","Household waste recycling has been widely considered the key to reducing the pollution caused by municipal solid waste and promoting sustainable development. This article aims to clarify the status and map the research trends in the field of household waste recycling. Bibliometric analysis is performed using bibliometrix based on publications during 1991–2020 in the Web of Science database. Results show that academic output in this field is growing rapidly. The top contributing authors, countries, institutions, and journals are identified. Collaboration network of authors, institutions, and countries are created and visualized. The most influential and cited articles in this field mainly focus on factors influencing residents’ recycling behavior from the perspectives of sociopsychology and economics. The theory of planned behavior is the most widely used psychological model. Other research hotspots include electronic waste, source separation, life cycle assessment, sustainability, organic waste, and circular economy. Studies on household waste recycling have become more and more comprehensive and interdisciplinary with the evolution of research themes. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.","Bibliometric analysis; Bibliometrix; Household recycling; Research trends; Science mapping; Waste management","domestic waste; human behavior; municipal solid waste; recycling; research work; sustainable development; trend analysis; waste management","","","","","","","Ma J., Hipel K.W., Exploring social dimensions of municipal solid waste management around the globe—A systematic literature review, Waste Manag, 56, pp. 3-12, (2016); Wang H., Liu X., Wang N., Zhang K., Wang F., Zhang S., Wang R., Zheng P., Matsushita M., Key factors influencing public awareness of household solid waste recycling in urban areas of China: A case study, Resour. Conserv. Recycl, 158, (2020); Troschinetz A.M., Mihelcic J.R., Sustainable recycling of municipal solid waste in developing countries, Waste Manag, 29, pp. 915-923, (2009); Ma J., Hipel K.W., Hanson M.L., Cai X., Liu Y., An analysis of influencing factors on municipal solid waste source-separated collection behavior in Guilin, China by using the theory of planned behavior, Sustain. Cities Soc, 37, pp. 336-343, (2018); Noor T., Javid A., Hussain A., Bukhari S.M., Ali W., Akmal M., Hussain S.M., Types, Sources and Management of Urban Wastes, pp. 239-263, (2020); Karak T., Bhagat R.M., Bhattacharyya P., Municipal solid waste generation, composition, and management: The world scenario, Crit. Rev. Environ. Sci. Technol, 42, pp. 1509-1630, (2012); Wang H., Nie Y., Municipal solid waste characteristics and management in China, J. Air Waste Manag. Assoc, 51, pp. 250-263, (2001); Knickmeyer D., Social factors influencing household waste separation: A literature review on good practices to improve the recycling performance of urban areas, J. Clean. Prod, 245, (2020); Gunaratne T., Krook J., Andersson H., Current practice of managing the waste of the waste: Policy, market, and organisational factors influencing shredder fines management in Sweden, Sustainability, 12, (2020); Saphores J.-D.M., Nixon H., How effective are current household recycling policies? Results from a national survey of U.S. households, Resour. Conserv. Recycl, 92, pp. 1-10, (2014); Zheng P., Zhang K., Zhang S., Wang R., Wang H., The door-to-door recycling scheme of household solid wastes in urban areas: A case study from Nagoya, Japan, J. Clean. Prod, 163, pp. S366-S373, (2017); Nelles M., Grunes J., Morscheck G., Waste management in Germany—Development to a sustainable circular economy?, Procedia Environ. Sci, 35, pp. 6-14, (2016); Wang H., Jiang C., Local nuances of authoritarian environmentalism: A legislative study on household solid waste sorting in China, Sustainability, 12, (2020); Wan C., Shen G.Q., Yu A., Key determinants of willingness to support policy measures on recycling: A case study in Hong Kong, Environ. Sci. Policy, 54, pp. 409-418, (2015); Lizin S., Van Dael M., Van Passel S., Battery pack recycling: Behaviour change interventions derived from an integrative theory of planned behaviour study, Resour. Conserv. Recycl, 122, pp. 66-82, (2017); Botetzagias I., Dima A.-F., Malesios C., Extending the theory of planned behavior in the context of recycling: The role of moral norms and of demographic predictors, Resour. Conserv. Recycl, 95, pp. 58-67, (2015); Miafodzyeva S., Brandt N., Recycling behaviour among householders: Synthesizing determinants via a meta-analysis, Waste Biomass Valorization, 4, pp. 221-235, (2012); Aboelmaged M., E-waste recycling behaviour: An integration of recycling habits into the theory of planned behaviour, J. Clean. Prod, 278, (2021); White K.M., Hyde M.K., The role of self-perceptions in the prediction of household recycling behavior in Australia, Environ. Behav, 44, pp. 785-799, (2011); Khan F., Ahmed W., Najmi A., Understanding consumers’ behavior intentions towards dealing with the plastic waste: Perspective of a developing country, Resour. Conserv. Recycl, 142, pp. 49-58, (2019); Wang Z., Guo D., Wang X., Determinants of residents’ e-waste recycling behaviour intentions: Evidence from China, J. Clean. Prod, 137, pp. 850-860, (2016); Hicks C., Dietmar R., Eugster M., The recycling and disposal of electrical and electronic waste in China—Legislative and market responses, Environ. Impact Assess. Rev, 25, pp. 459-471, (2005); Martin M., Williams I.D., Clark M., Social, cultural and structural influences on household waste recycling: A case study, Resour. Conserv. Recycl, 48, pp. 357-395, (2006); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr, 11, pp. 959-975, (2017); Li N., Han R., Lu X., Bibliometric analysis of research trends on solid waste reuse and recycling during 1992–2016, Resour. Conserv. Recycl, 130, pp. 109-117, (2018); Wu H., Zuo J., Zillante G., Wang J., Yuan H., Construction and demolition waste research: A bibliometric analysis, Archit. Sci. 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Econ, 48, pp. 419-442, (2000); Dahlen L., Vukicevic S., Meijer J.E., Lagerkvist A., Comparison of different collection systems for sorted household waste in Sweden, Waste Manag, 27, pp. 1298-1305, (2007); Hong S., The effects of unit pricing system upon household solid waste management: The Korean experience, J. Environ. Manag, 57, pp. 1-10, (1999); Bartelings H., Sterner T., Household waste management in a swedish municipality: Determinants of waste disposal, recycling and composting, Environ. Resour. Econ, 13, pp. 473-491, (1999); Knussen C., Yule F., MacKenzie J., Wells M., An analysis of intentions to recycle household waste: The roles of past behaviour, perceived habit, and perceived lack of facilities, J. Environ. Psychol, 24, pp. 237-246, (2004); Saphores J.-D.M., Nixon H., Ogunseitan O.A., Shapiro A.A., Household willingness to recycle electronic waste, Environ. Behav, 38, pp. 183-208, (2006); Chan K., Mass communication and pro-environmental behaviour: Waste recycling in Hong Kong, J. Environ. Manag, 52, pp. 317-325, (1998); Berglund C., The assessment of households’ recycling costs: The role of personal motives, Ecol. Econ, 56, pp. 560-569, (2006); Ajzen I., The theory of planned behavior, Organ. Behav. Hum. Decis. Process, 50, pp. 179-211, (1991); Boldero J., The prediction of household recycling of newspapers: The role of attitudes, intentions, and situational factors1, J. Appl. Soc. Psychol, 25, pp. 440-462, (1995); Passafaro P., Livi S., Kosic A., Local norms and the theory of planned behavior: Understanding the effects of spatial proximity on recycling intentions and self-reported behavior, Front. Psychol, 10, (2019); Vining J., Ebreo A., What makes a recycler?, Environ. Behav, 22, pp. 55-73, (2016); Jenkins R.R., Martinez S.A., Palmer K., Podolsky M.J., The determinants of household recycling: A material-specific analysis of recycling program features and unit pricing, J. Environ. Econ. Manag, 45, pp. 294-318, (2003); Fullerton D., Kinnaman T.C., Household responses to pricing garbage by the bag, Am. Econ. Rev, 86, pp. 971-984, (1996); Oskamp S., Harrington M.J., Edwards T.C., Sherwood D.L., Okuda S.M., Swanson D.C., Factors influencing household recycling behavior, Environ. Behav, 23, pp. 494-519, (1991); Hornik J., Cherian J., Madansky M., Narayana C., Determinants of recycling behavior: A synthesis of research results, J. Socio-Econ, 24, pp. 105-127, (1995); Schultz P.W., Oskamp S., Mainieri T., Who recycles and when? A review of personal and situational factors, J. Environ. Psychol, 15, pp. 105-121, (1995); Garfield E., Historiographic mapping of knowledge domains literature, J. Inf. Sci, 30, pp. 119-145, (2016); Hong S., Adams R.M., Household responses to price incentives for recycling: Some further evidence, Land Econ, 75, (1999); Hage O., Soderholm P., Berglund C., Norms and economic motivation in household recycling: Empirical evidence from Sweden, Resour. Conserv. Recycl, 53, pp. 155-165, (2009); Xie H., Zhang Y., Wu Z., Lv T., A bibliometric analysis on land degradation: Current status, development, and future directions, Land, 9, (2020); Rajendran S., Hodzic A., Scelsi L., Hayes S., Soutis C., AlMa'adeed M., Kahraman R., Plastics recycling: Insights into life cycle impact assessment methods, Plast. Rubber Compos, 42, pp. 1-10, (2013); Garfield E., Sher I.H., KeyWords Plus™—Algorithmic derivative indexing, J. Am. Soc. Inf. Sci, 44, pp. 298-299, (1993); Zhang J., Yu Q., Zheng F., Long C., Lu Z., Duan Z., Comparing keywords plus of WOS and author keywords: A case study of patient adherence research, J. Assoc. Inf. Sci. Technol, 67, pp. 967-972, (2016); Mori Y., Kuroda M., Makino N., Multiple Correspondence Analysis, pp. 21-28, (2016); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: A practical application to the Fuzzy Sets Theory field, J. Informetr, 5, pp. 146-166, (2011); Fernandez-Gonzalez J.M., Diaz-Lopez C., Martin-Pascual J., Zamorano M., Recycling organic fraction of municipal solid waste: Systematic literature review and bibliometric analysis of research trends, Sustainability, 12, (2020); Camon Luis E., Celma D., Circular economy. A review and bibliometric analysis, Sustainability, 12, (2020); Cahlik T., Comparison of the maps of science, Scientometrics, 49, pp. 373-387, (2000); Callon M., Courtial J.P., Laville F., Co-word analysis as a tool for describing the network of interactions between basic and technological research: The case of polymer chemsitry, Scientometrics, 22, pp. 155-205, (1991); Soundararajan K., Ho H.K., Su B., Sankey diagram framework for energy and exergy flows, Appl. Energy, 136, pp. 1035-1042, (2014)","Z. Zhang; Department of Environmental Science & Engineering, Fudan University, Shanghai, 200433, China; email: zhenzhang@fudan.edu.cn","","MDPI AG","","","","","","20711050","","","","English","Sustainability","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85107718734" -"Khasawneh N.; Al Rousan R.; Sujood","Khasawneh, Nermin (23501912900); Al Rousan, Ramzi (57734508000); Sujood (57237193200)","23501912900; 57734508000; 57237193200","Mapping global research on space tourism (1993–2022): a three-decade bibliometric assessment using R and VOSviewer","2024","Global Knowledge, Memory and Communication","","","","","","","2","10.1108/GKMC-01-2024-0027","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197388706&doi=10.1108%2fGKMC-01-2024-0027&partnerID=40&md5=b4c7736b9a1a5876a419d5c256be9941","Department of Sustainable Tourism, Faculty of Tourism and Heritage, The Hashemite University, Queen Rania, Zarqa, Jordan; Department of Tourism and Hospitality Management, Jamia Millia Islamia Central University, New Delhi, India","Khasawneh N., Department of Sustainable Tourism, Faculty of Tourism and Heritage, The Hashemite University, Queen Rania, Zarqa, Jordan; Al Rousan R., Department of Sustainable Tourism, Faculty of Tourism and Heritage, The Hashemite University, Queen Rania, Zarqa, Jordan; Sujood, Department of Tourism and Hospitality Management, Jamia Millia Islamia Central University, New Delhi, India","Purpose: Space tourism is currently experiencing significant attention because of its rapid and burgeoning development in the present era. This surge has resulted in an unprecedented growth in publications dedicated to unravelling the intricacies of space tourism. However, there is a conspicuous absence of a large-scale bibliometric analysis focusing on space tourism research from 1993 to 2022. Therefore, the aim of this study is to fill this research gap by examining and mapping the scholarly output published across the world in the spectrum of space tourism over the past 30 years (1993–2022). Design/methodology/approach: A corpus of 7,438 publications pertaining to space tourism published from 1993 to 2022 was gathered from the Web of Science Core Collection. Accordingly, bibliometrix package in R and VOSviewer software were used to conduct a comprehensive bibliometric analysis. Findings: The current study highlights a significant surge in publications related to space tourism, indicating a heightened scholarly interest and a significant paradigm shift in its exploration. Scott M. Smith, affiliated with National Aeronautics Space Administration Johnson Space Center, emerges as the most prolific author. Leading journals in disseminating space tourism research are Acta Astronautica and Aviation Space and Environmental Medicine. Keyword analysis revealed hotspots such as “space flight”, “simulated microgravity”, “weightlessness” and “stress”, while research gaps include “skylab”, “shuttle”, “cartilage”, “herpes virus” and “herniation”, offering potential avenues for exploration. Research limitations/implications: This study’s implications empower stakeholders with actionable insights and deepen the understanding of the evolving landscape of space tourism research, fostering an environment conducive to continuous exploration and innovation in this burgeoning field. Originality/value: This study enriches the understanding of global space tourism research and offers valuable insights applicable to a diverse audience, including researchers, policymakers and industry stakeholders. The broad applicability of the study’s findings underscores its significance, serving as a guide for strategic decision-making and shaping research agendas in the dynamic realm of space tourism. © 2024, Emerald Publishing Limited.","Bibliometrics; Performance analysis; Science mapping; Space tourism","","","","","","","","Anubha L., Hussain S., Gavinolla M.R., Gowreesunkar V.G., Swain S.K., Retrospective overview on global food tourism and related research: a bibliometric analysis, Journal of Foodservice Business Research, pp. 1-30, (2023); Atkinson L.Z., Cipriani A., How to carry out a literature search for a systematic review: a practical guide, BJPsych Advances, 24, 2, pp. 74-82, (2018); Birkle C., Pendlebury D.A., Schnell J., Adams J., Web of science as a data source for research on scientific and scholarly activity, Quantitative Science Studies, 1, 1, pp. 363-376, (2020); Chaudhuri S., Ray N., GIS Applications in the Tourism and Hospitality Industry, (2018); Correa L.M.C., Celis W.L., Montoya M.H., Fabra J.Q., Rojas O.C., Arias A.V., Bibliometric review on the use of geographic information systems in tourism, RISTI – Revista Iberica de Sistemas e Tecnologias de Informacao, pp. 651-663, (2021); Csomos G., Lengyel B., Mapping the efficiency of international scientific collaboration between cities worldwide, Journal of Information Science, 46, 4, pp. 575-578, (2020); Das A., Kondasani R.K.R., Deb R., Religious tourism: a bibliometric and network analysis, Tourism Review, 79, 3, pp. 622-634, (2023); Denis G., Alary D., Pasco X., Pisot N., Texier D., Toulza S., From new space to big space: How commercial space dream is becoming a reality, Acta Astronautica, 166, pp. 431-443, (2020); Dick S.J., Critical Issues in the History of Spaceflight, (2018); Dinc A., Bahar M., Topsakal Y., Ecotourism research: a bibliometric review, Tourism and Management Studies, 19, 1, pp. 29-40, (2023); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Duval D.T., Hall C.M., Space tourism. New destinations, new challenges, The Routledge Handbook of Tourism and Sustainability, (2015); Ercan F., Smart tourism destination: a bibliometric review, European Journal of Tourism Research, 34, (2023); Farooq R., Knowledge management and performance: a bibliometric analysis based on Scopus and WOS data (1988–2021), Journal of Knowledge Management, 27, 7, pp. 1948-1991, (2023); Farrukh M., Meng F., Raza A., Tahir M.S., Twenty‐seven years of sustainable development journal: a bibliometric analysis, Sustainable Development, 28, 6, pp. 1725-1737, (2020); Forganni A., The potential of space tourism for space popularisation: an opportunity for the EU space policy?, Space Policy, 41, pp. 48-52, (2017); Francisco J.S., International scientific collaborations: a key to scientific success, Angewandte Chemie International Edition, 54, 50, pp. 14984-14985, (2015); Gao Y., Chien S., Review on space robotics: toward top-level science through space exploration, Science Robotics, 2, 7, (2017); Gatti M., Ceccato I., Di Crosta A., La Malva P., Bartolini E., Palumbo R., Mammarella N., Assessing space tourism propensity: a new questionnaire for future space tourists, Aerospace, 10, 12, (2023); Giachino C., Pucciarelli F., Bollani L., Bonadonna A., Is generation Z ready to fly into space? The future of tourism is coming, Futures, (2022); Gulati S., I need some space!” deciphering space tourism discussions on social media, Global Knowledge, Memory and Communication, 72, 4-5, pp. 424-436, (2023); Habibi A., Mousavi M., Jamali S.M., Ale Ebrahim N., A bibliometric study of medical tourism, Anatolia, 33, 3, pp. 415-425, (2022); Hannonen O., In search of a digital nomad: defining the phenomenon, Information Technology and Tourism, 22, 3, pp. 335-353, (2020); Henderson I.L., Tsui W.H.K., The role of niche aviation operations as tourist attractions, Air Transport: A Tourism Perspective, pp. 233-244, (2019); Holloway J.C., Humphreys C., The Business of Tourism, (2022); Jiang Z., Zhao X., Wang Z., Herbert K., Safety leadership: a bibliometric literature review and future research directions, Journal of Business Research, 172, (2024); Khan A.U., Ma Z., Li M., Zhi L., Hu W., Yang X., from traditional to emerging technologies in supporting smart libraries. A bibliometric and thematic approach from 2013 to 2022, Library Hi Tech, (2023); Kim H., So K.K.F., Two decades of customer experience research in hospitality and tourism: a bibliometric analysis and thematic content analysis, International Journal of Hospitality Management, 100, (2022); Kim M.J., Hall C.M., Kwon O., Space tourism: do age and gender make a difference in risk perception?, Journal of Hospitality and Tourism Management, 57, pp. 13-17, (2023); Kumar V., Srivastava A., Mapping the evolution of research themes in business ethics: a co-word network analysis, VINE Journal of Information and Knowledge Management Systems, 53, 3, pp. 491-522, (2023); Kumar S., Valeri M., Kumar V., Kumar S., Bhatt I.K., Mapping the research trends on sports tourism and sustainability: a bibliometric analysis, Sport and Tourism, pp. 1-22, (2023); Lee T.S., Lee Y.S., Lee J., Chang B.C., Analysis of the intellectual structure of human space exploration research using a bibliometric approach: focus on human related factors, Acta Astronautica, 143, pp. 169-182, (2018); Lehto X.Y., Kirillova K., Wang D., Fu X., Convergence of boundaries in tourism, hospitality, events, and leisure: defining the core and knowledge structure, Journal of Hospitality and Tourism Research, 48, 3, pp. 407-419, (2024); Liu H., Yu Z., Chen C., Hong R., Jin K., Yang C., Visualization and bibliometric analysis of research trends on human fatigue assessment, Journal of Medical Systems, 42, 10, pp. 1-12, (2018); Maksoud A., Hussien A.A., Tatan L., Soliman E., Elmaghraby S., Simulation-Driven and Optimization-Based design of an architectural building: a case study of a space tourism building in the UAE, Buildings, 13, 12, (2023); Mehran J., Olya H., Han H., Psychology of space tourism marketing, technology, and sustainable development: from a literature review to an integrative framework, Psychology and Marketing, 40, 6, pp. 1130-1151, (2023); Pereira V., Bamel U., Charting the managerial and theoretical evolutionary path of AHP using thematic and systematic review: a decadal (2012–2021) study, Annals of Operations Research, 326, 2, pp. 635-651, (2023); Pomeroy C., Calzada-Diaz A., Bielicki D., Fund me to the moon: crowdfunding and the new space economy, Space Policy, 47, pp. 44-50, (2019); Rahaman S., Govil P., Khan D., Jevremov T.D., A 30-year bibliometric assessment and visualisation of emotion regulation research: applying network analysis and cluster analysis, Information Discovery and Delivery, (2023); Ramaano A.I., Prospects of using tourism industry to advance community livelihoods in Musina municipality, Limpopo, South Africa, Transactions of the Royal Society of South Africa, 76, 2, pp. 201-215, (2021); Ramaano A.I., Geographical information systems in sustainable rural tourism and local community empowerment: a natural resources management appraisal for Musina municipality’ society, Local Development and Society, 4, 1, pp. 74-105, (2023); Ramaano A.I., The implied significance of integrative geographical information systems in sustainable tourism and comprehensive community development in Musina municipality, South Africa, Technological Sustainability, 1, 1, pp. 42-63, (2022); Ramaano A.I., The economic-administrative role of geographic information systems in rural tourism and exhaustive local community development in African marginalized communities, Arab Gulf Journal of Scientific Research, 40, 2, pp. 180-195, (2022); Reddy G.M., Livina A., Hagan E., Wildlife tourism research in Africa: a bibliometric analysis, Sustainable Tourism Dialogues in Africa, 7, (2022); Reddy M.V., Nica M., Wilkes K., Space tourism: Research recommendations for the future of the industry and perspectives of potential participants, Tourism Management, 33, 5, pp. 1093-1102, (2012); Salas E., Tannenbaum S.I., Kozlowski S.W., Miller C.A., Mathieu J.E., Vessey W.B., Teams in space exploration: a new frontier for the science of team effectiveness, Current Directions in Psychological Science, 24, 3, pp. 200-207, (2015); Su Y., Mei J., Zhu J., Xia P., Li T., Wang C., Zhi J., You S., A global scientometric visualization analysis of rural tourism from 2000 to 2021, Sustainability, 14, 22, (2022); Sustacha Melijosa I.M., Banos Pino J.F., Valle Tuero E.A.D., An analysis of the research on smart tourism destinations based on bibliometric network visualisations, Investigaciones Turísticas, (2022); Tarifa-Fernandez J., Carmona-Moreno E., Sanchez-Fernandez R., An attempt to clarify what deserves to remain dark: a long look back, Tourism and Hospitality Research, 23, 4, (2022); Space tourism market size to grow by USD 6,959.36 million from 2023 to 2027: a descriptive analysis of customer landscape, vendor assessment, and market dynamics, (2023); Thommandru A., Espinoza-Maguina M., Ramirez-Asis E., Ray S., Naved M., Guzman-Avalos M., Role of tourism and hospitality business in economic development, Materials Today: Proceedings, 80, pp. 2901-2904, (2023); Vanegas J.C.P., Espinosa R.M., Candia J.G., Romero-Riano E., Palacios-Moya L., Padierna O., Development of research in information systems for tourism: a review focused on scientific visualization, RISTI – Revista Iberica de Sistemas e Tecnologias de Informacao, pp. 387-398, (2020); Wang G., Wang H., Wang L., Research trends in tourism and hospitality from 1991 to 2020: an integrated approach of corpus linguistics and bibliometrics, Journal of Hospitality and Tourism Insights, 6, 2, pp. 509-529, (2023); Wooten J.O., Tang C.S., Operations in space: exploring a new industry, Decision Sciences, 49, 6, pp. 999-1023, (2018); Zhang Y., Wang L., Wang J., Tian F., Progress and prospects for dark tourism research, Journal of Tourism and Cultural Change, 22, 1, pp. 1-25, (2023); Zhang S., Liang J., Su X., Chen Y., Wei Q., Research on global cultural heritage tourism based on bibliometric analysis, Heritage Science, 11, 1, (2023)","Sujood; Department of Tourism and Hospitality Management, Jamia Millia Islamia Central University, New Delhi, India; email: sjdkhancool@gmail.com","","Emerald Publishing","","","","","","25149342","","","","English","Glob. Knowl., Mem. Commun.","Article","Article in press","","Scopus","2-s2.0-85197388706" -"Pendse M.K.; Nerlekar V.S.; Darda P.","Pendse, Meenal Kaustubh (57956930900); Nerlekar, Varsha Shriram (57768978200); Darda, Pooja (57786656400)","57956930900; 57768978200; 57786656400","A comprehensive look at Greenwashing from 1996 to 2021: a bibliometric analysis","2023","Journal of Indian Business Research","15","1","","157","186","29","22","10.1108/JIBR-04-2022-0115","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141500630&doi=10.1108%2fJIBR-04-2022-0115&partnerID=40&md5=169652d607640dc4079b19d731350e5a","School of Management – PG, Dr. Vishwanath Karad MIT World Peace University, Pune, India","Pendse M.K., School of Management – PG, Dr. Vishwanath Karad MIT World Peace University, Pune, India; Nerlekar V.S., School of Management – PG, Dr. Vishwanath Karad MIT World Peace University, Pune, India; Darda P., School of Management – PG, Dr. Vishwanath Karad MIT World Peace University, Pune, India","Purpose: This paper aims to see how scholarly research on Greenwashing practices and behaviour has progressed in the 21st century. There has been a lot of empirical, exploratory and conceptual work done on Green marketing, sustainable marketing and environmental marketing. However, there have been few attempts to produce a comprehensive scientific mapping of Greenwashing as a niche topic. As a result, the study’s goal is to elicit research trends through knowledge structure synthesis. Design/methodology/approach: A Bibliometric Analysis on the topic of Greenwashing practices was undertaken on 355 publications. For this, a scientific search strategy was run on the Scopus database for the period 1996–2021. The study was conducted using Biblioshiny, a Web-based application that is part of the Bibliometric package. Important journals, countries, authors, keywords and affiliations were found using the software’s automated workflow and thematic evolution, citations, co-citations and social network analysis were performed. Findings: The study indicated a gradual increase in the research related to Greenwashing practices. The findings show a relative concentration of more influential work in the said domain amongst a handful of research scholars. Many influential studies have occurred after 2007, and a rally is seen in the studies on Greenwashing till 2020. The authors can say that the rigour of research has started increasing since then. Geographic dispersion of the work has shown that the USA followed by the UK dominates the scholarly inquiry and these countries have major collaboration with European and Asian researchers. The 10 most productive countries were examined, and it was discovered that the USA contributed the majority of the publications, with the UK and China coming in second and third place, respectively, in terms of publication in the said sector. In addition to the domain’s conceptual structure, the study exposes the domain’s social and Intellectual structure. This brings up new possibilities for Greenwashing studies in the future. Research limitations/implications: The present research is a Bibliometric analysis that is restricted to science mapping, and hence, limitations apply to the said studies. Researchers can use systematic literature review to build a robust conceptual foundation in the future. The Scopus database was used for this study because it has a greater number of high-quality journals in structured forms that are compatible with Bibliometrix software. Practical implications: Greenwashing practices and behaviour, as well as their links to sustainability, are discussed in this paper. It highlights the most often stated challenges in the discipline and suggests possible research topics. It provides future scholars with information on this discipline’s issues, contexts and collaboration opportunities. Social implications: The current study can give further directions to the researchers for conducting rigorous research on Greenwashing behaviour and practices and will guide the policymakers to formulate policies in the field of non-sustainable activities, with Greenwashing being one of them. Originality/value: A lot of work is done by the scientific community in Green marketing research, and a lot of literature is available on Green and Sustainable marketing practices. However, there is still a need felt for more extensive and rigorous research on the evolution of Greenwashing methods. This study makes a significant addition in that it brings together the scattered literature in the field, focuses on important sources, authors and documents, and investigates Greenwashing techniques and behaviour, which is the other side of the sustainable practices coin. © 2022, Emerald Publishing Limited.","Bibliometric analysis; Bibliometrix; Greenwashing; Non-sustainable practices; Science mapping; Sustainability","","","","","","","","Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Bansal P., Clelland I., Talking trash: legitimacy, impression management, and unsystematic risk in the context of the natural environment, Academy of Management Journal, 47, 1, pp. 93-103, (2004); Baum L.M., It’s not easy being green…or is it? 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Pendse; School of Management – PG, Dr. Vishwanath Karad MIT World Peace University, Pune, India; email: meenal.pendse@mitwpu.edu.in","","Emerald Publishing","","","","","","17554195","","","","English","J. Indian Bus. Stud.","Review","Final","","Scopus","2-s2.0-85141500630" -"Ranjbari M.; Shams Esfandabadi Z.; Shevchenko T.; Scagnelli S.D.; Lam S.S.; Varjani S.; Aghbashlo M.; Pan J.; Tabatabaei M.","Ranjbari, Meisam (57202871853); Shams Esfandabadi, Zahra (57217363297); Shevchenko, Tetiana (56647807400); Scagnelli, Simone Domenico (55190872200); Lam, Su Shiung (23035028500); Varjani, Sunita (56641777600); Aghbashlo, Mortaza (23970202200); Pan, Junting (56467567300); Tabatabaei, Meisam (26639886700)","57202871853; 57217363297; 56647807400; 55190872200; 23035028500; 56641777600; 23970202200; 56467567300; 26639886700","An inclusive trend study of techno-economic analysis of biofuel supply chains","2022","Chemosphere","309","","136755","","","","14","10.1016/j.chemosphere.2022.136755","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85139724644&doi=10.1016%2fj.chemosphere.2022.136755&partnerID=40&md5=a540705c866fb1656f12b26473250621","Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing, 100081, China; Department of Economics and Statistics “Cognetti de Martiis”, University of Turin, Lungo Dora Siena 100 A, Torino, 10153, Italy; Department of Environment, Land and Infrastructure Engineering (DIATI), Politecnico di Torino, Corso Duca Degli Abruzzi 24, Torino, 10129, Italy; Energy Center Lab, Politecnico di Torino, Via Paolo Borsellino 38/16, Torino, 10138, Italy; Scientific Department, Sumy National Agrarian University, 40031 Sumy, Ukraine; Laboratoire Genie Industriel, Université Paris-Saclay, CentraleSupélec, 91190 Gif-sur-Yvette, France; School of Business and Law, Edith Cowan University, 270 Joondalup Dr, Joondalup, 6027, Australia; Department of Management, University of Turin, Turin, Italy; Higher Institution Centre of Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries (AKUATROP), Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, Malaysia; Gujarat Pollution Control Board, Gujarat, Gandhinagar, 382 010, India; Department of Mechanical Engineering of Agricultural Machinery, Faculty of Agricultural Engineering and Technology, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran; Biofuel Research Team (BRTeam), Terengganu, Malaysia","Ranjbari M., Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing, 100081, China, Department of Economics and Statistics “Cognetti de Martiis”, University of Turin, Lungo Dora Siena 100 A, Torino, 10153, Italy; Shams Esfandabadi Z., Department of Environment, Land and Infrastructure Engineering (DIATI), Politecnico di Torino, Corso Duca Degli Abruzzi 24, Torino, 10129, Italy, Energy Center Lab, Politecnico di Torino, Via Paolo Borsellino 38/16, Torino, 10138, Italy; Shevchenko T., Scientific Department, Sumy National Agrarian University, 40031 Sumy, Ukraine, Laboratoire Genie Industriel, Université Paris-Saclay, CentraleSupélec, 91190 Gif-sur-Yvette, France; Scagnelli S.D., School of Business and Law, Edith Cowan University, 270 Joondalup Dr, Joondalup, 6027, Australia, Department of Management, University of Turin, Turin, Italy; Lam S.S., Higher Institution Centre of Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries (AKUATROP), Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, Malaysia; Varjani S., Gujarat Pollution Control Board, Gujarat, Gandhinagar, 382 010, India; Aghbashlo M., Department of Mechanical Engineering of Agricultural Machinery, Faculty of Agricultural Engineering and Technology, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran; Pan J., Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing, 100081, China; Tabatabaei M., Higher Institution Centre of Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries (AKUATROP), Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, Malaysia, Biofuel Research Team (BRTeam), Terengganu, Malaysia","Biofuels have gained much attention as a potentially sustainable alternative to fossil fuels to tackle climate change and energy scarcity. Hence, the increasing global interest in contributing to the biofuel supply chain (BSC), from biomass feedstock to biofuel production, has led to a huge amount of scientific production in recent years. In this vein, techno-economic analysis (TEA) of biofuel production to estimate total costs and revenues is highly important for transitioning towards a bioeconomy. This research aims to provide a comprehensive image of the body of knowledge in TEA evolution within the BSC domain. To this end, a systematic science mapping analysis, supported by a bibliometric analysis, is carried out on 1104 articles from 1986 to 2021. As a result, performance indicators of the scientific production within the target literature are presented to explain how this literature has evolved. Besides, thematic trends and conceptual structures of TEA of biofuel production are discovered. The results show that (i) biofuel production and consumption need promotion through tax measures and price subsidies, (ii) the development of cost-competitive algal biofuels has faced many challenges over recent years, and (iii) TEA of algal biofuels to identify commercial improvements and increase the economic feasibility is still lacking, which calls for more in-depth investigations. Consequently, current challenges and future perspectives of TEA in the BSC domain are rendered. The provided insights enable researchers and decision-makers involved in BSCs to (i) capture the most influential contributors to the field and (ii) identify major research hotspots and potential directions for further development. © 2022 Elsevier Ltd","Bibliometrix R-package; Biblioshiny; Biofuels; Biomass; Biorefinery; Techno-economic assessment","Biofuels; Biomass; Climate Change; Fossil Fuels; Climate change; Cost benefit analysis; Decision making; Economic analysis; Fossil fuels; Supply chains; biodiesel; bioethanol; biofuel; vegetable oil; fossil fuel; Algal biofuels; Alternative to fossil fuels; Bibliometrix R-package; Biblioshiny; Biofuel production; Biofuel supply chains; Biorefineries; Energy scarcity; Techno-Economic analysis; Techno-economic assessment; biofuel; biomass; climate change; evolution; fossil; supply chain management; alcohol production; anaerobic digestion; Article; bibliometrics; bioenergy; biofuel production; biotechnological production; chemical engineering; economic aspect; economic development; economic efficiency; economic evaluation; energy conversion; geographic distribution; greenhouse gas emission; life cycle assessment; microbial biomass; performance indicator; price; process model; process optimization; process technology; publication; renewable energy; tax; thematic analysis; trend study; biomass; climate change; Biofuels","","Biofuels, ; Fossil Fuels, ","","","Biofuel Research Team; Fundamental Research Funds for Central Non-profit Scientific Institution, (1610132020003); Ministry of Higher Education, Malaysia, MOHE; State Administration of Foreign Experts Affairs, SAFEA; Ministry of Agriculture, Food and Rural Affairs, MAFRA, (13220198); Chinese Academy of Agricultural Sciences, CAAS; National Key Research and Development Program of China, NKRDPC, (2018YFF3503); Institute of Tropical Aquaculture and Fisheries, University of Malaysia, Terengganu, AKUATROP, (56052)","The authors gratefully acknowledge financial support of National Key R&D Program of China (No. 2018YFF3503 ), Youth Talent Scholar of Chinese Academy of Agricultural Sciences , Fundamental Research Funds for Central Non-profit Scientific Institution (No. 1610132020003 ), Agricultural Science and Technology Innovation Project of Chinese Academy of Agricultural Sciences , Fund of Government purchase of services from Ministry of Agriculture and Rural Affairs (No. 13220198 ), Fund for talents from State Administration of Foreign Experts Affairs of P.R. China. M.T. would like to acknowledge the support from the Ministry of Higher Education, Malaysia , under the Higher Institution Centre of Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries ( AKUATROP ) program (Vot. no. 56052 , UMT/CRIM/2-2/5 Jilid 2 (11)), and the support by the Biofuel Research Team (BRTeam).","Abbasi M., Pishvaee M.S., Mohseni S., Third-generation biofuel supply chain: a comprehensive review and future research directions, J. Clean. Prod., 323, (2021); Agbo F.J., Oyelere S.S., Suhonen J., Tukiainen M., Scientific production and thematic breakthroughs in smart learning environments: a bibliometric analysis, Smart Learn. 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Pan; Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing, 100081, China; email: panjunting@caas.cn; M. Ranjbari; Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing, 100081, China; email: meisam.ranjbari@unito.it","","Elsevier Ltd","","","","","","00456535","","CMSHA","36209843","English","Chemosphere","Article","Final","","Scopus","2-s2.0-85139724644" -"Corrado S.; Scorza F.","Corrado, Simone (57219441338); Scorza, Francesco (35148454800)","57219441338; 35148454800","Emerging Technology Trends in Geocomputation Methods: A Literature Review","2023","Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)","14107 LNCS","","","510","520","10","1","10.1007/978-3-031-37114-1_35","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165041104&doi=10.1007%2f978-3-031-37114-1_35&partnerID=40&md5=1d912b4fc189b72a0b6221f5637ad957","School of Engineering, Laboratory of Urban and Regional Systems Engineering (LISUT), University of Basilicata, Potenza, Italy","Corrado S., School of Engineering, Laboratory of Urban and Regional Systems Engineering (LISUT), University of Basilicata, Potenza, Italy; Scorza F., School of Engineering, Laboratory of Urban and Regional Systems Engineering (LISUT), University of Basilicata, Potenza, Italy","The main focus of this paper is to present a systematic literature review on the emerging technology trends in geocomputation methods. The tools supporting planning have always been influenced by scientific and technological developments in other sectors. Actually, geospatial scientific research is advancing rapidly due to the development of new Machine Learning algorithms, increased in computing power and the size of geospatial Big-data. This has led to renewed interest in this line of research and the importance to have reliable techniques for SDI’s analysis and avoiding potential data biases in decision-making process. The paper analyzes the evolution of topics covered in the literature and highlights new research trends in geocomputation, including spatially explicit AI, GeoAI and Geographic Knowledge Graph. The results highlight that even though the geoAI topic is emerging, it already has a significant impact on the urban and regional planning discipline and the related scientific production. In conclusion, scientific mapping was discussed in order to assess the evolution of main research topics, identifying also the main research lab and the relevant active authors. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.","Bibliometrix; geoAI; Geographic Knowledge Graph; science mapping; spatially explicit AI","Computing power; Decision making; Knowledge graph; Learning algorithms; Machine learning; Regional planning; Bibliometrix; Emerging technologies; Geoai; Geocomputation; Geographic knowledge graph; Geographics; Knowledge graphs; Science mapping; Spatially explicit; Spatially explicit AI; Mapping","","","","","","","Murgante B., Borruso G., Lapucci A., Geocomputation and urban planning, Stud. Comput. Intell, 176, pp. 1-17, (2009); Keenan P.B., Jankowski P., Spatial decision support systems: Three decades on. Decis, Support Syst, 116, pp. 64-76, (2019); Casas G.L., Scorza F., Sustainable planning: A methodological toolkit, ICCSA 2016. 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Green Energy and Technology, pp. 163-177, (2018); Scorza F., Pontrandolfi P., Citizen participation and technologies: The C.A.S.T. architecture, ICCSA 2015. LNCS, Vol. 9156, pp. 747-755, (2015); Steinitz C., A Frame Work for Geodesign. Changing Geography by Design; ESRI, Ed, ESRI Press, (2012); Steinitz C., Orland B., Fisher T., Campagna M., Geodesign to address global change. Intell, Environ., pp. 193-242, (2023); Dastoli P.S., Pontrandolfi P., Scorza F., Corrado S., Azzato A., Applying geodesign towards an integrated local development strategy: The Val d’Agri case (Italy), ICCSA 2022. LNCS, Vol. 13379, Pp. 253–, (2022); Dangermond J., Goodchild M.F., Building geospatial infrastructure. Geo-Spat. Inf, Sci, 23, pp. 1-9, (2020); Arribas-Bel D., Rey S.J., Wolf, (2020); Liu X., Et al., Geographic information science in the era of geospatial big data: A cyberspace perspective, Innovation, 3, pp. 4-5, (2022); Corrado S., Scorza F., Machine learning based approach to assess territorial marginality, ICCSA 2022. LNCS, Vol. 13376, pp. 292-302, (2022); Corrado S., Santopietro L., Scorza, F.: Municipal Climate Adaptation Plans: An Assessment of the Benefit of Nature-Based Solutions for Urban Local Flooding Mitigation, (2022); Santopietro L., Scorza F., The Italian experience of the covenant of mayors: A territorial evaluation, Sustainability, 13, (2021); Fortunato G., Scorza F., Murgante B., Cyclable city: A territorial assessment procedure for disruptive policy-making on urban mobility, ICCSA 2019. LNCS, Vol. 11624, pp. 291-307, (2019); Scorza F., Saganeiti L., Pilogallo A., Murgante B., Ghost planning: The inefficiency of energy sector policies in a low population density region, Archivio Di Studi Urbani E Regionali, pp. 34-55, (2020); Scorza F., Pilogallo A., Saganeiti L., Murgante B., Pontrandolfi P., Comparing the territorial performances of renewable energy sources’ plants with an integrated ecosystem services loss assessment: A case study from the Basilicata region (Italy). Sustain, Cities Soc, 2, (2020); Pilogallo A., Scorza F., Ecosystem services multifunctionality: An analytical framework to support sustainable spatial planning in Italy, Sustainability, 14, (2022); Isola F., Lai S., Leone F., Zoppi C., Strengthening a regional green infrastructure through improved multifunctionality and connectedness: Policy suggestions from Sardinia, Italy, Sustainability, 14, (2022)","F. Scorza; School of Engineering, Laboratory of Urban and Regional Systems Engineering (LISUT), University of Basilicata, Potenza, Italy; email: francesco.scorza@unibas.it","Gervasi O.; Murgante B.; Scorza F.; Rocha A.M.A.C.; Garau C.; Karaca Y.; Torre C.M.","Springer Science and Business Media Deutschland GmbH","","23rd International Conference on Computational Science and Its Applications, ICCSA 2023","3 July 2023 through 6 July 2023","Athens","297179","03029743","978-303137113-4","","","English","Lect. Notes Comput. Sci.","Conference paper","Final","","Scopus","2-s2.0-85165041104" -"Razia S.; Ah S.H.B.A.B.","Razia, Sultana (57868790800); Ah, Siti Hajar Binti Abu Bakar (53064427900)","57868790800; 53064427900","Panoramic Mapping of Urban Social Sustainability: A 35-Year Bibliometric and Visualization Analysis","2022","Journal of Regional and City Planning","33","2","","49","78","29","1","10.5614/jpwk.2022.33.2.4","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137070278&doi=10.5614%2fjpwk.2022.33.2.4&partnerID=40&md5=a4aa8e90f3ae526108fb67364987572b","Department of Social Administration and Justice, Faculty of Arts and Social Sciences, University of Malaya, Malaysia","Razia S., Department of Social Administration and Justice, Faculty of Arts and Social Sciences, University of Malaya, Malaysia; Ah S.H.B.A.B., Department of Social Administration and Justice, Faculty of Arts and Social Sciences, University of Malaya, Malaysia","In recent years, ensuring social sustainability has been a global concern for sustainable urban development in both the academic arena and sustainability science. Many studies have been conducted in this area, but a bibliometric analysis has not yet been done previously. This study identified research streams and research hotspots in the urban social sustainability field based on a bibliometric analysis from 1985 to 2020, involving 1,623 documents from the Web of Science database. We used two software packages, Bibliometrix (Biblioshiny) and VOSviewer, for performance and science mapping analysis. The result showed that this research field is growing fast in multiple disciplines. In the publication trend analysis, we found significant changes since 2015. Analysis of leading countries and institutions revealed that developed countries are performing better than developing countries in producing publications on urban social sustainability. In the content analysis, we selected 214 documents and found that the survey method was the most used. Additionally, we found that 13.08 percent of papers (28 out of 214) used as many as 21 different theories, where ‘stakeholder theory,’ ‘planning theory,’ ‘theory of urbanism as a way of life,’ and ‘theory of good city form’ were significantly used. The findings of this study can assist researchers and practitioners by providing valuable insights into the research area of urban social sustainability. © 2020 ITB Institute for Research and Community Services.","Bibliometric; Biblioshiny; Mapping Analysis; Social Sustainability; Sustainable Urban Development; VOSviewer","","","","","","","","Ahvenniemi H., Huovila A., Pinto-Seppa I., Airaksinen M., What are the differences between sustainable and smart cities? [Article], Cities, 60, pp. 234-245, (2017); Akan M. O. A., Selam A. A., Assessment of social sustainability using social society index: A clustering application, European Journal of Sustainable Development, 7, 1, (2018); Ali H. H., Al-Betawi Y. N., Al-Qudah H. S., Effects of urban form on social sustainability – A case study of Irbid, Jordan, International Journal of Urban Sustainable Development, pp. 1-20, (2019); Ameen R. F. M., A framework for the sustainability assessment of urban design and development in iraqi cities, (2017); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of informetrics, 11, 4, pp. 959-975, (2017); Baffoe G., Mutisya E., Social sustainability: A review of indicators and empirical application, Environmental Management and Sustainable Development, 4, 2, (2015); Biscaro C., Giupponi C., Co-authorship and bibliographic coupling network effects on citations, Plos One, 9, 6, (2014); Booth A., Sutton A., Papaioannou D., Systematic approaches to a successful literature review, (2016); Bramley G., Dempsey N., Power S., Brown C., What is ‘social sustainability’, and how do our existing urban forms perform in nurturing it, Sustainable Communities and Green Futures’ Conference, (2006); Bramley G., Dempsey N., Power S., Brown C., Watkins D., Social sustainability and urban form: Evidence from five British cities, Environment and Planning A: Economy and Space, 41, 9, pp. 2125-2142, (2009); Burton E., Mitchell L., Inclusive urban design: Streets for life, (2006); Chen L., Zhao X., Tang O., Price L., Zhang S., Zhu W., Supply chain collaboration for sustainability: A literature review and future research agenda, International Journal of Production Economics, 194, pp. 73-87, (2017); Chiu R. L. H., Social equity in housing in the hong kong special administrative region: A social sustainability perspective, Sustainable development, 10, 3, pp. 155-162, (2002); Ciccullo F., Pero M., Caridi M., Gosling J., Purvis L., Integrating the environmental and social sustainability pillars into the lean and agile supply chain management paradigms: A literature review and future research directions, Journal of Cleaner Production, 172, pp. 2336-2350, (2018); Clark V. L. P., Creswell J. W., Understanding research: A consumer’s guide, (2014); Colantonio A., Social sustainability: An exploratory analysis of its definition, assessment methods, metrics and tools, (2007); Costanza R., Daly H. E., Natural capital and sustainable development [Article], Conservation Biology, 6, 1, pp. 37-46, (1992); Dave S., High densities in developing countries: A sustainable solution?, (2008); Dave S., Neighbourhood density and social sustainability in cities of developing countries, Sustainable development, 19, 3, pp. 189-205, (2011); Dempsey N., The influence of the quality of the built environment on social cohesion in english neighbourhoods, (2006); Dempsey N., Bramley G., Power S., Brown C., The social dimension of sustainable development: Defining urban social sustainability [Article], Sustainable development, 19, 5, pp. 289-300, (2011); Dempsey N., Brown C., Bramley G., The key to sustainable urban development in UK cities? The influence of density on social sustainability, Progress in Planning, 77, 3, pp. 89-141, (2012); Fu Y., Zhang X. L., Trajectory of urban sustainability concepts: A 35-year bibliometric analysis, Cities, 60, pp. 113-123, (2017); Garrigos-Simon F. J., Botella-Carrubi M. D., Gonzalez-Cruz T. F., Social capital, human capital, and sustainability: A bibliometric and visualization analysis, Sustainability, 10, 12, (2018); Ghalib A., Qadir A., Ahmad S. R., Evaluation of developmental progress in some cities of punjab, pakistan, using urban sustainability indicators, Sustainability, 9, 8, (2017); Godschalk D. R., Land use planning challenges: Coping with conflicts in visions of sustainable development and livable communities, Journal of the American Planning Association, 70, 1, pp. 5-13, (2004); Habitat U., State of the world’s cities. (The millenium development goals and urban sustainability, (2006); Hajirasouli A., Kumarasuriyar A., The social dimention of sustainability: Towards some definitions and analysis, Journal of Social Science for Policy Implications, 4, 2, pp. 23-34, (2016); Hutchins M. J., Sutherland J. W., An exploration of measures of social sustainability and their application to supply chain decisions, Journal of Cleaner Production, 16, 15, pp. 1688-1698, (2008); Jackson J. L., Kuriyama A., How often do systematic reviews exclude articles not published in English?, Journal of general internal medicine, 34, 8, pp. 1388-1389, (2019); Keesstra S. D., Bouma J., Wallinga J., Tittonell P., Smith P., Cerda A., Montanarella L., Quinton J. N., Pachepsky Y., van der Putten W. H., Bardgett R. D., Moolenaar S., Mol G., Jansen B., Fresco L. O., The significance of soils and soil science towards realization of the united nations sustainable development goals [Article], Soil, 2, 2, pp. 111-128, (2016); Kiamba A., The sustainability of urban development in developing economies, Consilience, 8, pp. 20-25, (2012); Kumar A., Anbanandam R., Development of social sustainability index for freight transportation system, Journal of Cleaner Production, 210, pp. 77-92, (2019); Li H., An H., Wang Y., Huang J., Gao X., Evolutionary features of academic articles co-keyword network and keywords co-occurrence network: Based on two-mode affiliation network, Physica A: Statistical Mechanics and its Applications, 450, pp. 657-669, (2016); Marvuglia A., Havinga L., Heidrich O., Fonseca J., Gaitani N., Reckien D., Advances and challenges in assessing urban sustainability: An advanced bibliometric review, Renewable and Sustainable Energy Reviews, 124, (2020); Meng L., Wen K.-H., Brewin R., Wu Q., Knowledge atlas on the relationship between urban street space and residents’ health: A bibliometric analysis based on vosviewer and citespace, Sustainability, 12, 6, (2020); Mengist W., Soromessa T., Legese G., Method for conducting systematic literature review and meta-analysis for environmental science research, MethodsX, 7, (2020); Mirzakhalili M., Rafieian M., Evaluation of social sustainability in urban neighbourhoods of Karaj City, International Journal of Architectural Engineering & Urban Planning, 24, 2, pp. 122-130, (2014); Mora L., Bolici R., Deakin M., The first two decades of smart-city research: A bibliometric analysis, Journal of Urban Technology, 24, 1, pp. 3-27, (2017); Murphy K., The social pillar of sustainable development: A literature review and framework for policy analysis, Sustainability: Science, Practice and Policy, 8, 1, pp. 15-29, (2012); Nations U., World economic situation prospects (wesp), (2020); Sustainable communities: Building for the future, (2003); Panda S., Chakraborty M., Misra S. K., Assessment of social sustainable development in urban India by a composite index, International Journal of Sustainable Built Environment, 5, 2, pp. 435-450, (2016); Sachs I., Social sustainability and whole development: Exploring the dimensions of sustainable development, Sustainability and the social sciences: A cross-disciplinary approach to integrating environmental considerations into theoretical reorientation, pp. 25-36, (1999); Sagaz S. M., Kneipp J. M., Lucietto D. A., Madruga L., Social dimension of sustainability and public health: A bibliometric analysis, Revista De Gestao Em Sistemas De Saude-Rgss, 7, 2, pp. 73-91, (2018); Satu S. A., Chiu R. L., Livability in dense residential neighbourhoods of Dhaka, Housing Studies, 34, 3, pp. 538-559, (2019); Small H., Co‐citation in the scientific literature: A new measure of the relationship between two documents, Journal of the American Society for information Science, 24, 4, pp. 265-269, (1973); Stren R., Polese M., Understanding the new sociocultural dynamics of cities: Comparative urban policy in a global context, The social sustainability of cities: diversity and the management of change, pp. 3-38, (2000); Tang M., Liao H. C., Wan Z. J., Herrera-Viedma E., Rosen M. A., Ten years of sustainability (2009 to 2018): A bibliometric overview, Sustainability, 10, 5, (2018); Report of the world commission on environment and development: ‘Our common future’, (1987); World urbanization prospects: The 2018 revision (ST/ESA/SER.A/420), (2019); Transforming our world: The 2030 agenda for sustainable development, (2015); Vallance S., Perkins H. C., Dixon J. E., What is social sustainability? A clarification of concepts, Geoforum, 42, 3, pp. 342-348, (2011); Vicente-Saez R., Martinez-Fuentes C., Open science now: A systematic literature review for an integrated definition, Journal of Business Research, 88, pp. 428-436, (2018); Waltman L., Van Eck N. J., Noyons E. C., A unified approach to mapping and clustering of bibliometric networks, Journal of informetrics, 4, 4, pp. 629-635, (2010); Wang C.-C., Ho Y.-S., Research trend of metal–organic frameworks: A bibliometric analysis, Scientometrics, 109, 1, pp. 481-513, (2016); Wang J. C., Kaskel S., Koh activation of carbon-based materials for energy storage [Article], Journal of Materials Chemistry, 22, 45, pp. 23710-23725, (2012); Wang M. H., Ho Y. S., Fu H. Z., Global performance and development on sustainable city based on natural science and social science research: A bibliometric analysis, Science of the Total Environment, 666, pp. 1245-1254, (2019); Wang Y. Q., Yuan G. H., Yan Y., Zhang X. L., Evaluation of sustainable urban development under environmental constraints: A case study of Jiangsu Province, China [Article], Sustainability, 12, 3, (2020); Weingaertner C., Moberg A., Exploring social sustainability: Learning from perspectives on urban development and companies and products, Sustainable development, 22, 2, pp. 122-133, (2014); Xie H., Zhang Y., Duan K., Evolutionary overview of urban expansion based on bibliometric analysis in web of science from 1990 to 2019, Habitat International, 95, (2020); Xie H., Zhang Y., Zeng X., He Y., Sustainable land use and management research: A scientometric review, Landscape Ecology, 35, 11, pp. 2381-2411, (2020); Zhang G., Xie S., Ho Y.-S., A bibliometric analysis of world volatile organic compounds research trends, Scientometrics, 83, 2, pp. 477-492, (2010)","S.H.B.A.B. Ah; Department of Social Administration and Justice, Faculty of Arts and Social Sciences, University of Malaya, Malaysia; email: shajar@um.edu.my","","ITB Journal Publisher","","","","","","25026429","","","","English","J. Reg. City Plan.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85137070278" -"Kumar V.; Patel S.; Sharma S.; Kumar R.; Kaur R.","Kumar, Vishal (57202530521); Patel, Sandeep (12752725000); Sharma, Siddhartha (56140108300); Kumar, Ritesh (57198684551); Kaur, Rishemjit (53986274600)","57202530521; 12752725000; 56140108300; 57198684551; 53986274600","Fifty Years of Cervical Myelopathy Research: Results from a Bibliometric Analysis","2022","Asian Spine Journal","16","6","","983","994","11","4","10.31616/asj.2021.0239","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146757147&doi=10.31616%2fasj.2021.0239&partnerID=40&md5=e1b723c077c46ac6ce4d5ef56d4d2f3f","Postgraduate Institute of Medical Education and Research, Chandigarh, India; CSIR-Central Scientific Instruments Organisation, Chandigarh, India; Academy of Scientific and Innovative Research, Ghaziabad, India","Kumar V., Postgraduate Institute of Medical Education and Research, Chandigarh, India; Patel S., Postgraduate Institute of Medical Education and Research, Chandigarh, India; Sharma S., Postgraduate Institute of Medical Education and Research, Chandigarh, India; Kumar R., CSIR-Central Scientific Instruments Organisation, Chandigarh, India, Academy of Scientific and Innovative Research, Ghaziabad, India; Kaur R., CSIR-Central Scientific Instruments Organisation, Chandigarh, India, Academy of Scientific and Innovative Research, Ghaziabad, India","We performed bibliometric analysis of the research papers published on clinical cervical spondylotic myelopathy (CSM) in the last 50 years. We extracted bibliometric data from Scopus and PubMed from 1970 to 2020 pertaining to clinical studies of CSM. The predominant journals, top cited articles, authors, and countries were identified using performance analysis. Science mapping was also performed to reveal the emerging trends, and conceptual and social structures of the authors and countries. Bibliometrix R-package was deployed for the study. The total numbers of clinical studies available in PubMed and Scopus were 1,302 and 3,470, respectively. The most cited article was published by Hilibrand AS, as observed in Scopus. Regarding the conceptual structure of the research, two main research themes were identified, one involving symptomatology, scientific-scale-based objective evaluation of symptoms, and surgical removal of the offending culprit, while the other was based on patho-etiology, relevant diagnostic modalities, and the surgery commonly performed for CSM. In terms of emerging trends, in recent times there is an increasing trend of scale-based objective evaluations, along with investigations of advanced nonoperative management. The United States is the most productive country, whereas Canada tops the list for inter-country collaboration. The trend of research showed a shift toward noninvasive procedures. © 2022 by Korean Society of Spine Surgery","Bibliometrics; Cervical spondylotic myelopathy; Conceptual structure; Performance mapping; Science mapping","","","","","","","","Bakhsheshian J, Mehta VA, Liu JC., Current diagnosis and management of cervical spondylotic myelopathy, Global Spine J, 7, pp. 572-586, (2017); Kumar GR, Ray DK, Das RK., Natural history, prevalence, and pathophysiology of cervical spondylotic myelopathy, Indian Spine J, 2, (2019); Salemi G, Savettieri G, Meneghini F, Et al., Prevalence of cervical spondylotic radiculopathy: a door-to-door survey in a Sicilian municipality, Acta Neurol Scand, 93, pp. 184-188, (1996); Nouri A, Tetreault L, Singh A, Karadimas SK, Fehlings MG., Degenerative cervical myelopathy: epidemiology, genetics, and pathogenesis, Spine (Phila Pa 1976), 40, pp. E675-E693, (2015); Kato S, Nouri A, Reihani-Kermani H, Oshima Y, Cheng J, Fehlings MG., Postoperative resolution of magnetic resonance imaging signal intensity changes and the associated impact on outcomes in degenerative cervical myelopathy: analysis of a global cohort of patients, Spine (Phila Pa 1976), 43, pp. 824-831, (2018); Bajamal AH, Kim SH, Arifianto MR, Et al., Posterior surgical techniques for cervical spondylotic myelopathy: WFNS Spine Committee recommendations, Neurospine, 16, pp. 421-434, (2019); Deora H, Kim SH, Behari S, Et al., Anterior surgical techniques for cervical spondylotic myelopathy: WFNS Spine Committee recommendations, Neurospine, 16, pp. 408-420, (2019); Maditati DR, Munim ZH, Schramm HJ, Kummer S., A review of green supply chain management: from bibliometric analysis to a conceptual framework and future research directions, Resour Conserv Recycl, 139, pp. 150-162, (2018); Fahimnia B, Sarkis J, Davarzani H., Green supply chain management: a review and bibliometric analysis, Int J Prod Econ, 162, pp. 101-114, (2015); Kalra G, Kaur R, Ichhpujani P, Chahal R, Kumar S., COVID-19 and ophthalmology: a scientometric analysis, Indian J Ophthalmol, 69, pp. 1234-1240, (2021); Koseoglu MA, Rahimi R, Okumus F, Liu J., Bibliometric studies in tourism, Ann Tour Res, 61, pp. 180-198, (2016); Fabregat-Aibar L, Barbera-Marine MG, Terceno A, Pie L., A bibliometric and visualization analysis of socially responsible funds, Sustainability, 11, (2019); Baraibar-Diez E, Luna M, Odriozola MD, Llorente I., Mapping social impact: a bibliometric analysis, Sustainability, 12, (2020); Sinha A, Dheerendra S, Munigangaiah S., 100 Top cited articles in cervical myelopathy: a bibliographic analysis, Spine (Phila Pa 1976), (2021); Aria M, Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, J informetr, 11, pp. 959-975, (2017); Yu J, Munoz-Justicia J., A bibliometric overview of twitter-related studies indexed in web of science, Future Internet, 12, (2020); Van Raan AF., Advances in bibliometric analysis: research performance assessment and science mapping, Bibliometr Use Abus Rev Res Perform, 87, pp. 17-28, (2014); Morris SA, Van der Veer Martens B., Mapping research specialties, Annu Rev Inf Sci Technol, 42, pp. 213-295, (2008); Elango B, Rajendran P, Authorship trends and collaboration pattern in the marine sciences literature: a scientometric study, Int J Inf Dissem Technol, 2, pp. 166-169, (2012); Sharma B, Boet S, Grantcharov T, Shin E, Barrowman NJ, Bould MD., The h-index outperforms other bibliometrics in the assessment of research performance in general surgery: a province-wide study, Surgery, 153, pp. 493-501, (2013); Bornmann L, Mutz R, Hug SE, Daniel HD., A multilevel meta-analysis of studies reporting correlations between the h index and 37 different h index variants, J Informetr, 5, pp. 346-359, (2011); Choudhri AF, Siddiqui A, Khan NR, Cohen HL., Understanding bibliometric parameters and analysis, Radiographics, 35, pp. 736-746, (2015); Braun T, Glanzel W, Schubert A., A Hirsch-type index for journals, Scientist, 19, (2005); Bailon-Moreno R, Jurado-Alameda E, Ruiz-Banos R, Courtial JP., Bibliometric laws: empirical flaws of fit, Scientometrics, 63, pp. 209-229, (2005); Ichhpujani P, Kalra G, Kaur R, Bhartiya S., Evolution of glaucoma research: a scientometric review, J Curr Glaucoma Pract, 14, pp. 98-105, (2020); Medline/PubMed data element (field) descriptions [Internet], (2019); Mora-Valentin EM, Ortiz-de-Urbina-Criado M, Najera-Sanchez JJ., Mapping the conceptual structure of science and technology parks, J Technol Transf, 43, pp. 1410-1435, (2018); Aparicio G, Iturralde T, Maseda A., Conceptual structure and perspectives on entrepreneurship education research: a bibliometric review, Eur Res Manag Bus Econ, 25, pp. 105-113, (2019); Le Roux B, Rouanet H., Multiple correspondence analysis, (2010); McCain KW., Mapping authors in intellectual space: a technical overview, J Am Soc Inf Sci, 41, pp. 433-443, (1990); Koseoglu MA., Growth and structure of authorship and co-authorship network in the strategic management realm: evidence from the Strategic Management Journal, BRQ Bus Res Q, 19, pp. 153-170, (2016); Qiu JP, Dong K, Yu HQ., Comparative study on structure and correlation among author co-occurrence networks in bibliometrics, Scientometrics, 101, pp. 1345-1360, (2014); Blondel VD, Guillaume JL, Lambiotte R, Lefebvre E., Fast unfolding of communities in large networks, J Stat Mech, 2008, (2008); Hilibrand AS, Carlson GD, Palumbo MA, Jones PK, Bohlman HH., Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis, J Bone Joint Surg Am, 81, pp. 519-528, (1999); Fountas KN, Kapsalaki EZ, Nikolakakos LG, Et al., Anterior cervical discectomy and fusion associated complications, Spine (Phila Pa 1976), 32, pp. 2310-2317, (2007); Mummaneni PV, Burkus JK, Haid RW, Traynelis VC, Zdeblick TA., Clinical and radiographic analysis of cervical disc arthroplasty compared with allograft fusion: a randomized controlled clinical trial, J Neu-rosurg Spine, 6, pp. 198-209, (2007); Heller JG, Sasso RC, Papadopoulos SM, Et al., Comparison of BRYAN cervical disc arthroplasty with anterior cervical decompression and fusion: clinical and radiographic results of a randomized, controlled, clinical trial, Spine (Phila Pa 1976), 34, pp. 101-107, (2009); Emery SE, Bohlman HH, Bolesta MJ, Jones PK., Anterior cervical decompression and arthrodesis for the treatment of cervical spondylotic myelopathy: two to seventeen-year follow-up, J Bone Joint Surg Am, 80, pp. 941-951, (1998); Goffin J, Geusens E, Vantomme N, Et al., Long-term follow-up after interbody fusion of the cervical spine, J Spinal Disord Tech, 17, pp. 79-85, (2004); Hurwitz EL, Carragee EJ, van der Velde G, Et al., Treatment of neck pain: noninvasive interventions: results of the Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders, Spine (Phila Pa 1976), 33, 4, pp. S123-S152, (2008); Benzel EC, Lancon J, Kesterson L, Hadden T., Cervical laminectomy and dentate ligament section for cervical spondylotic myelopathy, J Spinal Disord, 4, pp. 286-295, (1991); Katsuura A, Hukuda S, Saruhashi Y, Mori K., Kyphotic malalignment after anterior cervical fusion is one of the factors promoting the degenerative process in adjacent intervertebral levels, Eur Spine J, 10, pp. 320-324, (2001); Fraser JF, Hartl R., Anterior approaches to fusion of the cervical spine: a metaanalysis of fusion rates, J Neurosurg Spine, 6, pp. 298-303, (2007); Falagas ME, Pitsouni EI, Malietzis GA, Pappas G., Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses, FASEB J, 22, pp. 338-342, (2008); Shariff SZ, Bejaimal SA, Sontrop JM, Et al., Retrieving clinical evidence: a comparison of PubMed and Google Scholar for quick clinical searches, J Med Internet Res, 15, (2013)","R. Kaur; CSIR-Central Scientific Instruments Organisation, Chandigarh, India; email: rishemjit.kaur@csio.res.in","","Korean Society of Spine Surgery","","","","","","19761902","","","","English","Asian Spine J.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85146757147" -"Akin M.; Eyduran S.P.; Krauter V.","Akin, Melekşen (56661878900); Eyduran, Sadiye Peral (55666872700); Krauter, Victoria (57217089129)","56661878900; 55666872700; 57217089129","Bibliometric Literature Review on Sustainable Packaging","2022","Conference Proceedings - 23rd IAPRI World Conference on Packaging, IAPRI Bangkok 2022","","","","456","464","8","0","","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192512616&partnerID=40&md5=e9b8e2cdf5f1fce6231f99be9bbf6f94","Department of Horticulture, Iğdır University, Iğdır, 76 000, Turkey; Department of Horticulture, Muğla Sıtkı Koçman University, Fethiye, Turkey; Section Packaging and Resource Management, Department Applied Life Sciences, FH Campus Wien, University of Applied Sciences, Vienna, 1030, Austria","Akin M., Department of Horticulture, Iğdır University, Iğdır, 76 000, Turkey; Eyduran S.P., Department of Horticulture, Muğla Sıtkı Koçman University, Fethiye, Turkey; Krauter V., Section Packaging and Resource Management, Department Applied Life Sciences, FH Campus Wien, University of Applied Sciences, Vienna, 1030, Austria","We conducted a bibliometric analysis on scientific documents related to sustainable packaging. The literature was extracted from Web of Science database including restrictions on document type, language, and index which resulted in 220 documents published until 2021. The bibliographic data were analyzed utilizing Bibliometrix package available on R statistical software. The first document on sustainable packaging was published in 2006, and there was an increased trend of publications over time (7.11%). The core group consisted of seven out of 98 journals with Packaging Technology and Science, followed by Journal of Cleaner Production, and Sustainability publishing the highest number of documents in the field. The United States and Italy made the largest contribution on sustainable packaging research followed by India, Brazil, China, etc. All of the publications of France and Vietnam on the topic were in collaboration with other countries, whereas Denmark, Finland and Romania had only single country publications based on corresponding author country. Collaboration network analysis was performed to describe relationships between top countries on the area, which resulted in five distinct collaboration groups. The most frequent keywords projected with the word cloud after sustainable packaging, packaging and sustainability was circular economy. There was a shift from more general to more specific research topics over time as sustainable packaging and circular economy with a trend on biodegradable and mechanical properties emerged as unique terms beside packaging. The objective of this study is to evaluate conceptual, intellectual and social characteristics defining sustainable packaging, as well as to project research trends in this area performing descriptive and retrospective bibliometric analysis. © Conference Proceedings - 23rd IAPRI World Conference on Packaging, IAPRI Bangkok 2022. All rights reserved.","bibliometrix; network analysis; science mapping; sustainable packaging; thematic evolution","Packaging; Pollution control; Publishing; Bibliometric; Bibliometrics analysis; Bibliometrix; Circular economy; Literature reviews; Science mapping; Scientific documents; Sustainable packaging; Thematic evolution; Web of Science; Sustainable development","","","","","European Cooperation in Science and Technology, COST","This article/publication is based upon work from COST Action \u201CCA19124 Circul-a-bility\u201D (circulability.org), supported by COST (European Cooperation in Science and Technology). www.cost.eu.","Transforming Our World: The 2030 Agenda for Sustainable Development, (2015); The Circularity Gap Report 2021, Circle Economy, (2021); Crippa M., Et al., Food systems are responsible for a third of global anthropogenic GHG emissions, Nature Food, 2, 3, pp. 198-209, (2021); The Sustainable Development Goals Report 2021, (2021); Clune S., Crossin E., Verghese K., Systematic review of greenhouse gas emissions for different fresh food categories, Journal of Cleaner Production, 140, pp. 766-783, (2017); Molina-Besch K., Wikstrom F., Williams H., The environmental impact of packaging in food supply chains—does life cycle assessment of food provide the full picture?, The International Journal of Life Cycle Assessment, 24, 1, pp. 37-50, (2019); Garnett T., Where are the best opportunities for reducing greenhouse gas emissions in the food system (including the food chain)?, Food Policy, 36, pp. S23-S32, (2011); Nutrition and food systems. A report by the High Level Panel of Experts on Food Security and Nutrition of the Committee on World Food Security, (2017); Poore J., Nemecek T., Reducing food!s environmental impacts through producers and consumers, Science, 360, pp. 987-992, (2018); Floros J., Et al., Feeding the World Today and Tomorrow: The Importance of Food Science and Technology, Comprehensive Reviews in Food Science and Food Safety, 9, 5, pp. 572-599, (2010); Verghese K., Lewis H., Fitzpatrick L., Packaging for Sustainability, (2012); Guillard V., Et al., The Next Generation of Sustainable Food Packaging to Preserve Our Environment in a Circular Economy Context, Frontiers in Nutrition, (2018); Wikstrom F., Et al., Packaging Strategies That Save Food: A Research Agenda for 2030, Journal of Industrial Ecology, 23, 3, pp. 532-540, (2019); Lillford P., Hermansson A.-M., Global missions and the critical needs of food science and technology, Trends in Food Science & Technology, 111, pp. 800-811, (2021); Robertson G., Food Packaging and Shelf Life, (2009); Robertson G., Food packaging: Principles and practice, (2013); Soroka W., Fundamentals of packaging technology: Fifth Edition, Inst of Packaging Professionals, (2014); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Broadus R.N., Toward a definition of ""bibliometrics”, Scientometrics, 12, 5, pp. 373-379, (1987); Crane D., Invisible colleges: Diffusion of knowledge in scientific communities, (1972); Forliano C., De Bernardi P., Yahiaoui D., Entrepreneurial universities: A bibliometric analysis within the business and management domains, Technological Forecasting and Social Change, 165, (2021); R: A language and environment for statistical computing, (2021); Rodriguez-Rojas A., Et al., ¿What is the new about food packaging material? A bibliometric review during 1996–2016, Trends in Food Science & Technology, 85, pp. 252-261, (2019); Vila-Lopez N., Kuster-Boluda I., A bibliometric analysis on packaging research: Towards sustainable and healthy packages, British Food Journal, 123, 2, (2021); Shi S., Yin J., Global research on carbon footprint: A scientometric review, Environmental Impact Assessment Review, 89, (2021); Nemat B., Et al., The Role of Food Packaging Design in Consumer Recycling Behavior—A Literature Review, Sustainability, 11, 16, (2019); Bradford S., Sources of information on specific subjects, Engineering, 137, pp. 85-86, (1934)","M. Akin; Department of Horticulture, Iğdır University, Iğdır, 76 000, Turkey; email: akinmeleksen@gmail.com","","Thailand Institute of Scientific and Technological Research","et al.; GrainPro; PerkinElmer; Propak Asia; SCGP; Singha Corporation","23rd IAPRI World Conference on Packaging, IAPRI Bangkok 2022","12 June 2022 through 16 June 2022","Bangkok","199191","","978-974953464-9","","","English","Conf. Proc. - IAPRI World Conf. Packag., IAPRI Bangkok","Conference paper","Final","","Scopus","2-s2.0-85192512616" -"Farooq R.","Farooq, Rayees (56536529900)","56536529900","Knowledge management and performance: a bibliometric analysis based on Scopus and WOS data (1988–2021)","2023","Journal of Knowledge Management","27","7","","1948","1991","43","70","10.1108/JKM-06-2022-0443","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144239101&doi=10.1108%2fJKM-06-2022-0443&partnerID=40&md5=6a6e7471119d4e233565d724e9e39e07","Faculty of Business, Sohar University, Sohar, Oman","Farooq R., Faculty of Business, Sohar University, Sohar, Oman","Purpose: This study aims to analyze the trends manifested in literature from the area of knowledge management and performance, with emphasis on bibliometric analysis. Design/methodology/approach: To explore the studies focused on the area under investigation, the authors performed a search in ISI Web of Science and Scopus using the combination of keywords such as “Knowledge management” AND “Performance.” Generally, this study covered a period of 33 years, from 1988 to 2021 because the first study was published in 1970 and the databases have not covered all the journals and studies which date back to the early 1970s or 1980s. The final data set comprised 1,583 publications with 40 articles removed during the screening and eligibility process. Findings: The results of the bibliometric analysis indicate that the interest in the area of knowledge management and performance has significantly increased, especially from 2000 to 2021. The application of bibliometric analysis on the relationship between knowledge management and performance uncovered various themes, productive authors and widely cited documents. The study highlighted how the knowledge management–performance relationship has evolved over the years and how the interplay between knowledge management and performance may help the firms in gaining the sustainable competitive advantage. Originality/value: To the best of the author’s knowledge, this study is the first of its kind to conduct the bibliometric analysis on knowledge management and performance. This study can be a starting point for scholars interested in understanding how knowledge management is related to performance. © 2022, Emerald Publishing Limited.","Bibliometric analysis; Bibliometrix; Biblioshiny; Knowledge management; Performance; Performance analysis; Science mapping; Scopus; WOS","","","","","","","","Abeh A., Talib N.A., Mohammed S., Knowledge management processes and organisational performance: a systematic review, International Journal of Knowledge Management Studies, 12, 4, pp. 352-374, (2021); Acedo F.J., Casillas J.C., Current paradigms in the international management field: an author co-citation analysis, International Business Review, 14, 5, pp. 619-639, (2005); Adams G.L., Lamont B.T., Knowledge management systems and developing sustainable competitive advantage, Journal of Knowledge Management, 7, 2, pp. 142-154, (2003); Agostini L., Nosella A., Sarala R., Spender J.C., Wegner D., Tracing the evolution of the literature on knowledge management in inter-organizational contexts: a bibliometric analysis, Journal of Knowledge Management, 24, 2, pp. 463-490, (2020); Agrifoglio R., Metallo C., Di Nauta P., Understanding knowledge management in public organizations through the organizational knowing perspective: a systematic literature review and bibliometric analysis, Public Organization Review, 21, 1, pp. 137-156, (2021); Aguillo I.F., Is Google Scholar useful for bibliometrics? 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Jacso P., Metadata mega mess in Google Scholar, Online Information Review, 34, 1, pp. 175-191, (2010); Kakhki M.D., Mousavi R., Razi M.A., Tarn J.M., Antecedents and performance implications of knowledge management in supply chains: a meta-analysis, International Journal of Knowledge Management Studies, 12, 4, pp. 392-428, (2021); Kalling T., Knowledge management and the occasional links with performance, Journal of Knowledge Management, 7, 3, pp. 67-81, (2003); Kim Y.J., Hancer M., The effect of knowledge management resource inputs on organizational effectiveness in the restaurant industry, Journal of Hospitality and Tourism Technology, 1, 2, pp. 174-189, (2010); Kluge J., Stein W., Licht T., Knowledge Unplugged: The McKinsey and Company Global Survey on Knowledge Management, (2001); Kumar B., Sharma A., Vatavwala S., Kumar P., Digital mediation in business-to-business marketing: a bibliometric analysis, Industrial Marketing Management, 85, pp. 126-140, (2020); Lancichinetti A., Fortunato S., Consensus clustering in complex networks, Scientific Reports, 2, 1, pp. 1-7, (2012); Lee H., Choi B., Knowledge management enablers, processes, and organizational performance: an integrative view and empirical examination, Journal of Management Information Systems, 20, 1, pp. 179-228, (2003); Lee J.H., Kim Y.G., A stage model of organizational knowledge management: a latent content analysis, Expert Systems with Applications, 20, 4, pp. 299-311, (2001); Lee K.C., Lee S., Kang I.W., KMPI: measuring knowledge management performance, Information & Management, 42, 8, pp. 469-482, (2005); Lee S., Kim B.G., Kim H., An integrated view of knowledge management for performance, Journal of Knowledge Management, 16, 2, pp. 183-203, (2012); Li E.Y., Liao C.H., Yen H.R., Co-authorship networks and research impact: a social capital perspective, Research Policy, 42, 9, pp. 1515-1530, (2013); Liu G., Tsui E., Kianto A., Revealing deeper relationships between knowledge management leadership and organisational performance: a meta-analytic study, Knowledge Management Research & Practice, pp. 1-15, (2022); Lu H., Feng Y., A measure of authors’ centrality in co-authorship networks based on the distribution of collaborative relationships, Scientometrics, 81, 2, pp. 499-511, (2009); Mardani A., Nikoosokhan S., Moradi M., Doustar M., The relationship between knowledge management and innovation performance, The Journal of High Technology Management Research, 29, 1, pp. 12-26, (2018); Marques D.P., Simon F.J.G., The effect of knowledge management practices on firm performance, Journal of Knowledge Management, 10, 3, pp. 143-156, (2006); Mat S.R.T., Ab Razak M.F., Kahar M.N.M., Arif J.M., Mohamad S., Firdaus A., Towards a systematic description of the field using bibliometric analysis: malware evolution, Scientometrics, 126, 3, pp. 2013-2055, (2021); Mougenot B., Doussoulin J.P., Conceptual evolution of the bioeconomy: a bibliometric analysis, Environment, Development and Sustainability, 24, 1, pp. 1031-1047, (2022); Naranan S., Bradford's law of bibliography of science: an interpretation, Nature, 227, 5258, pp. 631-632, (1970); Nonaka I., A dynamic theory of organizational knowledge creation, Organization science, 5, 1, pp. 14-37, (1994); Nonaka I., Takeuchi H., The knowledge-creating company, Harvard Business Review, 85, 7-8, (2007); Omotehinwa T.O., Examining the developments in scheduling algorithms research: a bibliometric approach, Heliyon, 8, 5, (2022); Paswan A.K., Wittmann C.M., Knowledge management and franchise systems, Industrial Marketing Management, 38, 2, pp. 173-180, (2009); Persson O., Danell R., Schneider J.W., How to use bibexcel for various types of bibliometric analysis, Celebrating Scholarly Communication Studies: A Festschrift for Olle Persson at His 60th Birthday, 5, pp. 9-24, (2009); Pritchard A., Statistical bibliography or bibliometrics, Journal of Documentation, 25, 4, pp. 348-349, (1969); Qamar Y., Samad T.A., Human resource analytics: a review and bibliometric analysis, Personnel Review, 51, 1, pp. 251-283, (2022); Singh K.P., Chander H., Publication trends in library and information science, Library Management, 35, 3, pp. 134-149, (2014); Singh S.K., Role of leadership in knowledge management: a study, Journal of Knowledge Management, 12, 4, pp. 3-15, (2008); Teece D.J., Pisano G., Shuen A., Dynamic capabilities and strategic management, Strategic Management Journal, 18, 7, pp. 509-533, (1997); Tseng S.M., Knowledge management system performance measure index, Expert Systems with Applications, 34, 1, pp. 734-745, (2008); Van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Van Eck N.J., Waltman L., CitNetExplorer: a new software tool for analyzing and visualizing citation networks, Journal of Informetrics, 8, 4, pp. 802-823, (2014); Walczak S., Knowledge management and organizational learning: an international research perspective, The Learning Organization, 15, 6, pp. 486-494, (2008); Wallace D., Knowledge Management: Historical and Cross-Disciplinary Themes, (2007); Wang C.L., Ahmed P.K., Rafiq M., Knowledge management orientation: construct development and empirical validation, European Journal of Information Systems, 17, 3, pp. 219-235, (2008); Wong K.Y., Tan L.P., Lee C.S., Wong W.P., Knowledge management performance measurement: measures, approaches, trends and future directions, Information Development, 31, 3, pp. 239-257, (2015); Yu D., Xu Z., Wang X., Bibliometric analysis of support vector machines research trend: a case study in China, International Journal of Machine Learning and Cybernetics, 11, 3, pp. 715-728, (2020); Zack M., McKeen J., Singh S., Knowledge management and organizational performance: an exploratory analysis, Journal of Knowledge Management, 13, 6, pp. 392-409, (2009); Alexander P.A., Judy J.E., The interaction of domain-specific and strategic knowledge in academic performance, Review of Educational Research, 58, 4, pp. 375-404, (1988)","R. Farooq; Faculty of Business, Sohar University, Sohar, Oman; email: rayeesfarooq@rediffmail.com","","Emerald Publishing","","","","","","13673270","","","","English","J. Knowl. Manag.","Review","Final","","Scopus","2-s2.0-85144239101" -"Bohara S.; Bisht V.; Suri P.; Panwar D.; Sharma J.","Bohara, Sailaja (57820580300); Bisht, Vashali (59550938700); Suri, Pradeep (58331793900); Panwar, Diksha (57211860230); Sharma, Jyoti (59551395100)","57820580300; 59550938700; 58331793900; 57211860230; 59551395100","Online marketing and brand awareness for HEI: A review and bibliometric analysis","2024","F1000Research","12","","76","","","","1","10.12688/f1000research.127026.2","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186142568&doi=10.12688%2ff1000research.127026.2&partnerID=40&md5=1b04d3d54d3eea23268ff9873dff6f51","Uttaranchal Institute of Management, Uttaranchal University, Uttarakhand, Dehradun, India; Institute of Professional Studies and Development, Kumaun University, Naintal, India; IILM Graduate School of Management, Uttar Pradesh, Noida, India; DAV Centenary College, Haryana, Faridabad, India","Bohara S., Uttaranchal Institute of Management, Uttaranchal University, Uttarakhand, Dehradun, India; Bisht V., Institute of Professional Studies and Development, Kumaun University, Naintal, India; Suri P., Uttaranchal Institute of Management, Uttaranchal University, Uttarakhand, Dehradun, India; Panwar D., IILM Graduate School of Management, Uttar Pradesh, Noida, India; Sharma J., DAV Centenary College, Haryana, Faridabad, India","Background: This study conducted a comprehensive bibliometric analysis to identify the gaps in the existing literature related to Online marketing and brand awareness strategies for HEI. It has evaluated the current state of the literature on the given topic showing the pivotal role of online marketing and brand awareness in higher education for enrollment. Methods: The study used a web-based application, Biblioshiny, which comes in the bibliometrix package. The study used the Scopus database to create the data set, given its conventional construction and quality of the sources. The analysis done is descriptive. By using the bibliometrix software, the study showed the authors name, articles, sources, citations, relevant journals and co-citation from the year 2017 to 2022. The time period selected by the study was five years which means that articles published from 2017 to 2022 have been taken for the study. Results: We found that HEI online marketing and brand awareness have not been explored much as it has not reached the stage of maturity. Most of the publication was done during the time of Covid-19. Also, the role of brand awareness in student enrollment decisions for HEI requires more investigation. Top most publications their sources and top authors are identified. Conclusions: Bibliometric analysis has provided valuable insights into the seminal work, emerging trends, and the gap in the study. This area of study has been explored but not as much as challenges, and the effectiveness of online marketing tools like seo, sem,ppc and more has not been measured. Further, this paper allows researchers to study by examining the pattern of publications by seeing the different authorships, co-authors, collaborations, relevant sources, and citations. The insights of this paper will help education policymakers devise more creative strategies to increase enrollment, ensuring sustained relevance and competitive advantage in higher education institutions. Copyright: © 2024 Bohara S et al.","analysis; Bibliometrix; Brand awareness; Enrollment; Higher education institutions; Online marketing; Science mapping; Technology","Awareness; Bibliometrics; Humans; Internet; Marketing; Social Media; Universities; Article; awareness; bibliometrics; brand awareness; coronavirus disease 2019; data analysis; data visualization; education; education program; higher education institutions; human; marketing; online marketing; pandemic; publication; systematic review; awareness; Internet; social media; university","","","R statistical packages","","","","Abbas A.S., Brand Loyalty of Higher Education Institutions, Marketing and Management of Innovations, 1, 4, pp. 46-56, (2019); Alexa L., Alexa M., Stoica M.C., The Use of Online Marketing and Social Media in Higher Education Institutions in Romania, Journal of Marketing Research and Case Studies, pp. 1-9, (2012); Aral S., Dellarocas C., Godes D., Introduction to the Special Issue—Social Media and Business Transformation: A Framework for Research, Information Systems Research, 24, 1, pp. 3-13, (2013); Aristovnik A., Kerzic D., Ravselj D., Et al., Impacts of the COVID-19 Pandemic on Life of Higher Education Students: A Global Perspective, Sustainability, 12, (2020); Ashan A., Determining Students’ Choice Factors for Selecting Higher Private Education Institution, Asian Journal of Applied Science and Engineering, 6, 2, (2017); Bohara S., Gupta A., Panwar D., Relationship Between Factors of Online Marketing and Student Enrollment Decisions in Higher Education: An Analysis Using Structural Modeling Techniques, International Journal of Online Marketing, 12, 1, pp. 1-18, (2022); Bohara S., Suri P., Panwar D., Impact of brand awareness on enrollment decision process moderated by students’ gender for HEI, Journal of Content, Community and Communication, 15, 8, (2022); Bohara S., Suri P., Panwar D., Et al., (2022); Brooks R., Gupta A., Jayadeva S., Et al., Students’ views about the purpose of higher education: a comparative analysis of six European countries, Higher Education Research & Development, 40, pp. 1375-1388, (2020); 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Zhang X., The Influences Of Brand Awareness On Consumers’ Cognitive Process: An Event-Related Potentials Study, Frontiers in Neuroscience, 14, (2020)","S. Bohara; Uttaranchal Institute of Management, Uttaranchal University, Dehradun, Uttarakhand, India; email: Sailajabohara1@gmail.com","","F1000 Research Ltd","","","","","","20461402","","","39931162","English","F1000 Res.","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85186142568" -"Mabele M.B.; Kasongi N.; Nnko H.; Mwanyoka I.; Kiwango W.A.; Makupa E.","Mabele, Mathew Bukhi (57191837185); Kasongi, Ng'winamila (57219393108); Nnko, Happiness (56436577200); Mwanyoka, Iddi (35776791700); Kiwango, Wilhelm Andrew (57195680511); Makupa, Enock (56707377000)","57191837185; 57219393108; 56436577200; 35776791700; 57195680511; 56707377000","Inequalities in the production and dissemination of biodiversity conservation knowledge on Tanzania: A 50-year bibliometric analysis","2023","Biological Conservation","279","","109910","","","","21","10.1016/j.biocon.2023.109910","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85149728141&doi=10.1016%2fj.biocon.2023.109910&partnerID=40&md5=0cd2993912274480bca85bf53ecbd9d0","Department of Geography and Environmental Studies, University of Dodoma, Dodoma, Tanzania; Department of Biology, University of Dodoma, Dodoma, Tanzania; Centre of African Studies, University of Cambridge, United Kingdom","Mabele M.B., Department of Geography and Environmental Studies, University of Dodoma, Dodoma, Tanzania, Centre of African Studies, University of Cambridge, United Kingdom; Kasongi N., Department of Geography and Environmental Studies, University of Dodoma, Dodoma, Tanzania; Nnko H., Department of Biology, University of Dodoma, Dodoma, Tanzania; Mwanyoka I., Department of Geography and Environmental Studies, University of Dodoma, Dodoma, Tanzania; Kiwango W.A., Department of Geography and Environmental Studies, University of Dodoma, Dodoma, Tanzania; Makupa E., Department of Geography and Environmental Studies, University of Dodoma, Dodoma, Tanzania","Tanzania is a popular keyword in biodiversity conservation publications, but, trends in research collaborations, scientific knowledge production and authors' productivity remain underexplored. Using the Web of Science database and bibliometric analysis techniques, we fill this gap by examining the trends between 1972 and 2021. The database search produced 1517 records. We filtered the data using document types and subject categories as criteria. We used bibliometrix package in R software to analyse 1354 peer-reviewed publications. Through performance analysis, science mapping and network analysis, journal publications, author and institutional productivity, disciplinary focus, funding agencies and network of authorship and institutional collaborations are identified. Whereas African Journal of Ecology, PLoS One and Biological Conservation top the scientific production list, Biological Conservation, Conservation Biology and Oryx top the citation list. Major research inequalities are revealed where, European and North American centricity dominates in author productivity (number of papers, total citations and h-index), author collaborations networks and research funding agencies. Out of the top 20 highly cited papers, eleven had no Tanzanian author. The list had only two papers with Tanzanians as first authors. We observed a proliferation of international researchers and decreased productivity of local researchers in the last 30 years. Organisations from Europe and North America provided much of the research funding in Tanzania. This is possibly one of the first attempts to illustrate empirically how production and dissemination of conservation knowledge are entrenched in unequal structures at a country level. We thus contribute to the burgeoning literature on decolonisation of conservation research, by proposing five practical areas to dismantle the unequal system of knowledge production. © 2023 Elsevier Ltd","Bibliometric analysis; Biodiversity conservation; Decolonising conservation; North-South collaborations; Research trends; Tanzania","Europe; North America; Tanzania; biodiversity; conservation status; decolonization; equity; institutional framework; knowledge; software; spatiotemporal analysis","","","","","","","Aleixandre-Benavent R., Aleixandre-Tudo J.L., Castello-Cogollos, Aleixandre J.L., Trends in global research in deforestation. A bibliometric analysis, Land Use Policy, 72, pp. 293-302, (2018); Apostolopoulou E., Chatzimentor A., Maestre-Andres S., Requena-i-Mora, Pizarro A., Bormpoudakis D., Reviewing 15 years of research on neoliberal conservation: towards a decolonial, interdisciplinary, intersectional and community-engaged research agenda, Geoforum, 124, pp. 236-256, (2021); Asase A., Mzumara-Gawa T.I., Owingo J.O., Peterson A.T., Saupe E., Replacing “parachute science” with “global science” in ecology and conservation biology, Conserv. Sci. Pract., 4, 5, (2021); Barabasi A.-L., Albert R., Emergence of scaling in random networks, Science, 286, pp. 509-512, (1999); Bennett N.J., Roth R., Klain S.C., Chan K., Christie P., Clark D.A., Cullman G., Curran D., Durbin T.J., Epstein G., Greenberg A., Nelson M.P., Sandlos J., Stedman R., Teel T.R., Thomas R., Verissimo D., Wyborn C., Conservation social science: understanding and integrating human dimensions to improve conservation, Biol. Conserv., 205, pp. 93-108, (2017); Binka F., North-south research collaborations: a move towards a true partnership?, Tropical Med. Int. Health, 10, 3, pp. 207-209, (2005); Brockington D., Noe C., Ponte S., Contested sustainability, Contested Sustainability: The Political Ecology of Conservation and Development in Tanzania, pp. 287-302, (2022); Collins Y.A., Maguire-Rajpaul V.A., Krauss J.E., Asiyanbi A.P., Jimenez A., Mabele M.B., Alexander-Owen M., Plotting the coloniality of conservation, J. Political Ecol., 28, 1, (2021); Corbera E., Maestre-Andres S., Calvet-Mir L., Brockington D., Howe C., Adams W.A., Biases in the production of knowledge on ecosystem services and poverty alleviation, Oryx, 55, 6, pp. 868-877, (2021); Dahdouh-Guebas F., Ahimbisibwe J., Moll R.V., Koedam N., Neo-colonial science by the most industrialised upon the least developed countries in peer-reviewed publishing, Scientometrics, 56, 3, pp. 329-343, (2003); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, J. Bus. Res., 133, pp. 285-296, (2021); Genda P.A., Ngoteya H.C., Caro T., Mulder M.B., Looking up and down: string collaborations is only the first step in tackling parachute science, Conserv. Sci. Pract., 4, (2022); Health T.L.G., Closing the door on parachutes and parasites, Lancet Glob. Health, 6, (2018); Hicks C.C., Levine A., Agrawal A., Carothers C., Charnley S., Coulthard S., Dolsak N., Donatuto J., Garcia-Quijano C., Mascia M.B., Norman K., Poe M.R., Satterfield T., Martin K., Levin P.S., Engage key social concepts for sustainability, Science, 352, 6281, pp. 38-40, (2016); Hsieh H., Shannon S.E., Three approaches to qualitative content analysis, Qual. Health Res., 15, 9, pp. 1277-1288, (2005); Huang L., Zhou M., Lv J., Chen K., Trends in global research in forest carbon sequestration: a bibliometric analysis, J. Clean. Prod., 252, (2020); Leader-Williams N., Adams W.A., Smith R.J., Trade-offs in Conservation: Deciding What to Save, (2011); Li N., Han R., Lu X., Bibliometric analysis of research trends on solid waste reuse and recycling during 1922–2016, Resour. Conserv. Recy., 130, pp. 109-117, (2018); Liu X., Zhang L., Hong S., Global biodiversity research during 1900–2009: a bibliometric analysis, Biodivers. Conserv., 20, pp. 807-826, (2011); Mongeon P., Paul-Hus A., The journal coverage of web of science and scopus: a comparative analysis, Scientometrics, 106, pp. 213-228, (2016); Myers N., Mittermeier R.A., Mittermeier C.G., da Fonseca G.A.B., Kent J., Biodiversity hotspots for conservation priorities, Nature, 403, pp. 853-858, (2000); Nunez M.A., Chiuffo M.C., Pauchard A., Zenni R.D., Making ecology really global, Trends Ecol. Evol., 36, 9, pp. 766-769, (2021); Overland I., Sagbakken H.F., Isataeva A., Kolodzinskaia G., Simpson N.P., Trisos C., Vakulchuk R., Funding flows for climate change research on Africa: where do they come from and where do they go?, Clim. Dev., (2021); Pototsky P.C., Cresswell W., Conservation research output in sub-saharan Africa is increasing, but only in a few countries, Oryx, 55, 6, pp. 924-933, (2020); Pritchard A., Statistical bibliography or bibliometrics, J. Doc., 25, (1969); R Core Team, R: A language and environment for statistical computing, (2022); Rands M.R.W., Adams W.A., Bennun L., Butchart S.H.M., Clements A., Coomes D., Entwistle A., Kapos V., Scharlemann J.P.W., Sutherland W.J., Vira B., Biodiversity conservation: challenges beyond 2010, Science, 329, 5997, pp. 1298-1303, (2010); Stefanoudis P.V., Licuanan W.Y., Morrison T.H., Talma S., Veitayaki J., Woodall L.C., Turning the tide of parachute science, Curr. Biol., 31, 4, pp. R161-R185, (2021); Tilley E., Kalina M., “My flight arrives at 5 am, can you pick me up?” The gatekeeping burden of the African academic, J. Afr. Cult. Stud., 33, 4, pp. 538-548, (2021); Trisos C.H., Auerbach J., Katti M., Decoloniality and anti-oppressive practices for a more ethical ecology, Nat. Ecol. Evol., 5, pp. 1205-1212, (2021); National Biodiversity Strategy and Action Plan 2015–2020, (2015); Urassa M., Lawson D.W., Wamoyi J., Gurmu E., Gibson M.A., Madhivanan P., Placek C., Cross-cultural research must prioritize equitable collaboration, Nat. Hum. Behav., 5, pp. 668-671, (2021); de Vos A., The problem of ‘colonial science’. Sci. Am, (2020); Wang Q., Waltman L., Large-scale analysis of the accuracy of the journal classification systems of web of science and scopus, J. Informetr., 10, pp. 347-364, (2016); Wang Z., Zhao Y., Wang B., A bibliometric analysis of climate change adaptation based on massive literature data, J. Clean. Prod., 199, pp. 1072-1082, (2018); Wang B., Zhang Q., Cui F., Scientific research on ecosystem services and human well-being: a bibliometric analysis, Ecol. Indic., 125, (2021); Wilson K.A., Auerbach N.A., Sam K., Magini A.G., Moss A.S.L., Langhans S.D., Budiharta S., Terzano D., Meijaard E., Conservation research is not happening where it is most needed, PLoS Biol., 14, 3, (2016); Zhang X., Estoque R.C., Xie H., Murayama Y., Ranagalage M., Bibliometric analysis of highly cited articles on ecosystem services, PLoS One, 14, 2, (2019)","M.B. Mabele; Department of Geography and Environmental Studies, University of Dodoma, Dodoma, Tanzania; email: mathew.bukhi@udom.ac.tz","","Elsevier Ltd","","","","","","00063207","","BICOB","","English","Biol. Conserv.","Review","Final","","Scopus","2-s2.0-85149728141" -"Hassan T.; Saleh M.I.","Hassan, Thowayeb (57219937671); Saleh, Mahmoud Ibraheam (57222984549)","57219937671; 57222984549","Tourism digital detox and digital-free tourism: What do we know? What do we not know? Where should we be heading?","2024","Journal of Tourism Futures","","","","","","","1","10.1108/JTF-12-2023-0274","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198507981&doi=10.1108%2fJTF-12-2023-0274&partnerID=40&md5=480c95bfc943c317e7c7037165560f1a","Social Studies Department, Faculty of Art, College of Arts, King Faisal University, Al-Ahsa, Saudi Arabia; Faculty of Tourism and Hotel Management, Helwan University, Helwan, Egypt; Tourism Studies Department, Faculty of Tourism and Hotel Management, Helwan University, Helwan, Egypt","Hassan T., Social Studies Department, Faculty of Art, College of Arts, King Faisal University, Al-Ahsa, Saudi Arabia, Faculty of Tourism and Hotel Management, Helwan University, Helwan, Egypt; Saleh M.I., Tourism Studies Department, Faculty of Tourism and Hotel Management, Helwan University, Helwan, Egypt","Purpose: While past research has begun exploring digital-free tourism, tourism digital detox and their benefits, no study to date has comprehensively mapped trends, findings and limitations across this growing body of literature. This study aims to conduct the first bibliometric analysis and systematic literature review to address this gap. Design/methodology/approach: This study utilized a mixed methodology of bibliometric analysis and systematic literature review. Structured search strings were applied to databases to identify relevant papers, which were screened according to inclusion criteria. Bibliometric analysis of included papers was performed using Bibliometrix, an R package enabling network visualization, statistical tests and science mapping. This allowed the identification of significant topics, theories, methods, citations and publication trends over time. Findings: The results clearly show that factors previously lacking attention in past tourism research, such as the interplay between online and offline experiences during travel, are emerging as important determinants of travelers' well-being. This study outlines the current state of scholarship on managing technology's impacts on travelers' psychological and social needs. Specifically, we found limited research integrating how digital detox tools shape pre-trip planning, on-site activities and post-trip sharing of travel experiences. Originality/value: This is the first study to comprehensively map trends and findings in digital-free tourism and tourism digital detox research using a blended bibliometric analysis and systematic literature review methodology. It offers vital direction toward strengthening theoretical understanding and supporting balanced connectivity and fulfillment for all tourists going forward. By addressing limitations, this research approach helps develop this area of scholarship in a unified manner. © 2024, Thowayeb Hassan and Mahmoud Ibraheam Saleh.","Digital detox; Digital-free tourism; Technology overload; Tourism digitalization; Tourism experience; Tourist well-being","","","","","","Vice Presidency for Graduate Studies and Scientific Research; Deanship of Scientific Research, King Faisal University, DSR; King Faisal University, KFU, (029)","This work was supported by the Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia [Grant No. 029].","Arenas Escaso J.F., Folgado Fernandez J.A., Palos Sanchez P.R., Digital disconnection as an opportunity for the tourism business: a bibliometric analysis, Emerging Science Journal, 6, 5, pp. 1100-1113, (2022); Ayeh J.K., Distracted gaze: problematic use of mobile technologies in vacation contexts, Tourism Management Perspectives, 26, pp. 31-38, (2018); Bastidas-Manzano A.B., Sanchez-Fernandez J., Casado-Aranda L.A., The past, present, and future of smart tourism destinations: a bibliometric analysis, Journal of Hospitality and Tourism Research, 45, 3, pp. 529-552, (2021); Cai W., McKenna B., Power and resistance: digital-free tourism in a connected world, Journal of Travel Research, 62, 2, pp. 290-304, (2023); Cai W., McKenna B., Waizenegger L., Turning it off: emotions in digital-free travel, Journal of Travel Research, 59, 5, pp. 909-927, (2020); Choi Y., Hickerson B., Lee J., Lee H., Choe Y., Digital tourism and wellbeing: conceptual framework to examine technology effects of online travel media, International Journal of Environmental Research and Public Health, 19, 9, (2022); Clark C., Nyaupane G.P., Understanding Millennials' nature-based tourism experience through their perceptions of technology use and travel constraints, Journal of Ecotourism, 22, 3, pp. 339-353, (2023); Coca-Stefaniak J.A., Beyond smart tourism cities–towards a new generation of ‘wise’ tourism destinations, Journal of Tourism Futures, 7, 2, pp. 251-258, (2021); Conti E., Farsari I., Disconnection in nature-based tourism experiences: an actor-network theory approach, Annals of Leisure Research, pp. 1-18, (2022); Dickinson J.E., Hibbert J.F., Filimonau V., Mobile technology and the tourist experience:(Dis) connection at the campsite, Tourism Management, 57, pp. 193-201, (2016); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: an overview and guidelines, Journal of Business Research, 133, pp. 285-296, (2021); Echchakoui S., Why and how to merge Scopus and web of science during bibliometric analysis: the case of sales force literature from 1912 to 2019, Journal of Marketing Analytics, 8, 3, pp. 165-184, (2020); Egger I., Lei S.I., Wassler P., Digital free tourism–An exploratory study of tourist motivations, Tourism Management, 79, (2020); Fan X., Liu A., The effects of online and face-to-face experiential value co-creation on tourists' wellbeing, ENTER 2020, pp. 8-10, (2020); Fan D.X., Buhalis D., Lin B., A tourist typology of online and face-to-face social contact: destination immersion and tourism encapsulation/decapsulation, Annals of Tourism Research, 78, (2019); Floros C., Cai W., McKenna B., Ajeeb D., Imagine being off-the-grid: Millennials' perceptions of digital-free travel, Journal of Sustainable Tourism, 29, 5, pp. 751-766, (2021); Guleria D., Kaur G., Bibliometric analysis of ecopreneurship using VOSviewer and RStudio Bibliometrix, 1989-2019, Library Hi Tech, 39, 4, pp. 1001-1024, (2021); Hassan T.H., Salem A.E., Saleh M.I., Digital-Free tourism holiday as a new approach for tourism well-being: tourists' attributional approach, International Journal of Environmental Research and Public Health, 19, 10, (2022); Hjalager A.M., Flagestad A., Innovations in well-being tourism in the Nordic countries, Current Issues in Tourism, 15, 8, pp. 725-740, (2012); Hu H.F., Liu Y., Digital-free tourism intention: the effects of message concreteness and intervention, Tourism Analysis, 28, 3, pp. 505-510, (2023); Knani M., Echchakoui S., Ladhari R., Artificial intelligence in tourism and hospitality: bibliometric analysis and research agenda, International Journal of Hospitality Management, 107, (2022); Lachance J., The experience of disconnecting from information and communication technology (ict) while traveling in late modernity, Tourism Culture and Communication, 22, 1, pp. 1-11, (2022); Lee S.M.F., Filep S., Vada S., King B., Webcam travel: a preliminary examination of psychological well-being, Tourism and Hospitality Research, (2022); Li J., Pearce P.L., Low D., Media representation of digital-free tourism: a critical discourse analysis, Tourism Management, 69, pp. 317-329, (2018); Li J., Pearce P.L., Oktadiana H., Can digital-free tourism build character strengths?, Annals of Tourism Research, 85, (2020); Liu Y., Hu H.F., Digital-free tourism intention: a technostress perspective, Current Issues in Tourism, 24, 23, pp. 3271-3274, (2021); McKenna B., Waizenegger L., Cai W., The influence of personal and professional commitments on digitally disconnected experiences, IFIP International Conference on Human Choice and Computers, pp. 305-314, (2020); McLean G., Aldossary M., Digital tourism consumption: the role of virtual reality (VR) vacations on consumers' psychological wellbeing: an abstract, Academy of Marketing Science Annual Conference, pp. 143-144, (2022); Moisa D.G., Michopoulou E., IT and Well-Being in Travel and Tourism, pp. 1715-1741, (2022); Mura P., Wijesinghe S.N., Critical theories in tourism–a systematic literature review, Tourism Geographies, 25, 2-3, pp. 487-507, (2023); Nutz M., Leifheit L., Computer science unplugged: developing and evaluating a “traveling salesperson problem” board game, European Conference on Games Based Learning, (2021); Ozdemir M.A., Goktas L.S., Research trends on digital detox holidays: a bibliometric analysis, 2012-2020, Tourism and Management Studies, 17, 3, pp. 21-35, (2021); Pahlevan-Sharif S., Mura P., Wijesinghe S.N., A systematic review of systematic reviews in tourism, Journal of Hospitality and Tourism Management, 39, pp. 158-165, (2019); Pawlowska-Legwand A., Matoga L., Disconnect from the digital world to reconnect with the real life: an analysis of the potential for development of unplugged tourism on the example of Poland, Tourism Planning and Development, 18, 6, pp. 649-672, (2021); Rahmani Z., Mackenzie S.H., Carr A., How virtual wellness retreat experiences may influence psychological well-being, Journal of Hospitality and Tourism Management, 58, pp. 516-524, (2023); Rosenberg H., The ‘flashpacker’ and the ‘unplugger’: cell phone (dis) connection and the backpacking experience, Mobile Media and Communication, 7, 1, pp. 111-130, (2019); Sintobin T., Traveller, tourist and the ‘lost art of travelling’: the debate continues, Routledge Handbook of the Tourist Experience, pp. 215-234, (2021); Staheli U., Stoltenberg L., Digital detox tourism: practices of analogization, New Media and Society, (2022); Stankov U., Filimonau V., Technology-assisted mindfulness in the co-creation of tourist experiences, Handbook of E-Tourism, pp. 1-26, (2020); Stodolska M., Lee K., Hwang S., Lee Y., Son H., Leisure and family quality of life in Korean transnational split families, Leisure Sciences, pp. 1-21, (2023); Syvertsen T., Offline tourism: digital and screen ambivalence in Norwegian mountain huts with no internet access, Scandinavian Journal of Hospitality and Tourism, 22, 3, pp. 195-209, (2022); Tanti A., Buhalis D., The influences and consequences of being digitally connected and/or disconnected to travellers, Information Technology and Tourism, 17, 1, pp. 121-141, (2017); Wong B.K.M., Hazley S.A.S.A., The future of health tourism in the industrial revolution 4.0 era, Journal of Tourism Futures, 7, 2, pp. 267-272, (2020); Zhang M., Zhang X., Between escape and return: rethinking daily life and travel in selective unplugging, Tourism Management, 91, (2022)","T. Hassan; Social Studies Department, Faculty of Art, College of Arts, King Faisal University, Al-Ahsa, Saudi Arabia; email: Thassan@kfu.edu.sa; M.I. Saleh; Tourism Studies Department, Faculty of Tourism and Hotel Management, Helwan University, Helwan, Egypt; email: mahmoudibraheam580@gmail.com","","Emerald Publishing","","","","","","20555911","","","","English","J. Tour. Futur.","Article","Article in press","All Open Access; Gold Open Access","Scopus","2-s2.0-85198507981" -"Tsilika K.","Tsilika, Kyriaki (6506532108)","6506532108","Exploring the Contributions to Mathematical Economics: A Bibliometric Analysis Using Bibliometrix and VOSviewer","2023","Mathematics","11","22","4703","","","","15","10.3390/math11224703","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178375323&doi=10.3390%2fmath11224703&partnerID=40&md5=cf9163c036dbe188351b5ee73b189aa9","School of Economics and Business, Department of Economics, Volos, 382 21, Greece; School of Social Sciences, Department of Business Administration, Hellenic Open University, Patras, 263 35, Greece","Tsilika K., School of Economics and Business, Department of Economics, Volos, 382 21, Greece, School of Social Sciences, Department of Business Administration, Hellenic Open University, Patras, 263 35, Greece","From Cournot, Walras, and Pareto’s research to what followed in the form of marginalist economics, chaos theory, agent-based modeling, game theory, and econophysics, the interpretation and analysis of economic systems have been carried out using a broad range of higher mathematics methods. The evolution of mathematical economics is associated with the most productive and influential authors, sources, and countries, as well as the identification of interactions between the authors and research topics. Bibliometric analysis provides journal-, author-, document-, and country-level metrics. In the present study, a bibliometric overview of mathematical economics came from a screening performed in September 2023, covering the timespan 1898–2023. About 6477 documents on mathematical economics were retrieved and extracted from the Scopus academic database for analysis. The Bibliometrix package in the statistical programming language R was employed to perform a bibliometric analysis of scientific literature and citation data indexed in the Scopus database. VOSviewer (version 1.6.19) was used for the visualization of similarities using several bibliometric techniques, including bibliographic coupling, co-citation, and co-occurrence of keywords. The analysis traced the most influential papers, keywords, countries, and journals among high-quality studies in mathematical economics. © 2023 by the author.","bibliometric analysis; Bibliometrix; mathematical economics; science mapping; VOSviewer","","","","","","","","Chiang A., Fundamental Methods of Mathematical Economics, (1984); Quddus M., Rashid S., The Overuse of Mathematics in Economics: Nobel Resistance, East. Econ. J, 20, pp. 251-265, (1994); Wald A., On Some Systems of Equations of Mathematical Economics, Econometrica, 19, (1951); Hudson M., The Use and Abuse of Mathematical Economics, J. Econ. Stud, 27, pp. 292-315, (2000); Fisher I., Cournot and Mathematical Economics, Q. J. Econ, 12, pp. 119-138, (1898); Gary-Bobo R., Cournot, A Great Forerunner of Mathematical Economics, Eur. Econ. Rev, 33, pp. 515-522, (1989); Ragni L., Applying Mathematics to Economics According to Cournot and Walras, Eur. J. Hist. Econ. Thought, 25, pp. 73-105, (2018); Johnson W.E., The Pure Theory of Utility Curves, Econ. J, 23, pp. 483-513, (1913); Edgeworth F.Y., Recent Contributions to Mathematical Economics, I. Econ. J, 25, pp. 36-63, (1915); Edgeworth F.Y., Recent Contributions to Mathematical Economics, Econ. J, 25, pp. 189-203, (1915); Debreu G., Mathematical Economics: Twenty Papers of Gerard Debreu, (1983); Debreu G., Theoretic Models: Mathematical Form and Economic Content, Econometrica, 54, pp. 1259-1270, (1986); Arrow K.J., Debreu G., Existence of an Equilibrium for a Competitive Economy, Econometrica, 22, pp. 265-290, (1954); Debreu G., Economic Theory in the Mathematical Mode, Scand. J. Econ, 86, pp. 393-410, (1984); Debreu G., The Mathematization of Economic Theory, Am. Econ. Rev, 81, pp. 1-7, (1991); Robertson R.M., Mathematical Economics before Cournot, J. Political Econ, 57, pp. 523-536, (1949); Hurwitz L., Mathematics in Economics: Language and Instrument, Mathematics and the Social Sciences, (1963); Theocharis R.D., Early Developments in Mathematical Economics, (1983); Theocharis R.D., The Development of Mathematical Economics the Years of Transition: From Cournot to Jevons, (1993); Katzner D.W., Why Mathematics in Economics?, J. Post. Keynes. Econ, 25, pp. 561-574, (2003); Tarasov V.E., Tarasova V.V., Dynamic Keynesian Model of Economic Growth with Memory and Lag, Mathematics, 7, (2019); Tarasov V.E., On History of Mathematical Economics: Application of Fractional Calculus, Mathematics, 7, (2019); Mokhov V., Aliukov S., Alabugin A., Osintsev K., A Review of Mathematical Models of Macroeconomics, Microeconomics, and Government Regulation of the Economy, Mathematics, 11, (2023); Dow S.C., Understanding the Relationship between Mathematics and Economics, J. Post. Keynes. Econ, 25, pp. 547-560, (2003); Jeschke C., Kuhn C., Lindmeier A., Zlatkin-Troitschanskaia O., Saas H., Heinze A., What Is the Relationship between Knowledge in Mathematics and Knowledge in Economics?, Z. Fur Padagog, 65, pp. 511-524, (2019); Espinosa M., Rondon C., Romero M., The Use of Mathematics in Economics and Its Effect on a Scholar’s Academic Career; Stigler G.J., Stigler S.M., Friedland C., The Journals of Economics, J. Political Econ, 103, pp. 331-359, (1995); Hodgson G., On the Complexity of Economic Reality and the History of the Use of Mathematics in Economics, Filos. De La Econ, 1, pp. 25-45, (2013); Broadus R.N., Toward a Definition of “Bibliometrics, Scientometrics, 12, pp. 373-379, (1987); Bar-Ilan J., Informetrics at the Beginning of the 21st Century—A Review, J. Informetr, 2, pp. 1-52, (2008); Kaas R., Laeven R., Lin S., Tang Q., Willmot G., Yang H., IME’s Editorial Board, Insur. Math. Econ, 78, pp. A1-A3, (2018); Burnham J.F., Scopus Database: A Review, Biomed. Digit. Libr, 3, (2006); Baas J., Schotten M., Plume A., Cote G., Karimi R., Scopus as a Curated, High-Quality Bibliometric Data Source for Academic Research in Quantitative Science Studies, Quant. Sci. Stud, 1, pp. 377-386, (2020); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to Conduct a Bibliometric Analysis: An Overview and Guidelines, J. Bus. Res, 133, pp. 285-296, (2021); Aria M., Cuccurullo C., Bibliometrix: An R-Tool for Comprehensive Science Mapping Analysis, J. Informetr, 11, pp. 959-975, (2017); van Eck N.J., Waltman L., Software Survey: VOSviewer, a Computer Program for Bibliometric Mapping, Scientometrics, 84, pp. 523-538, (2010); van Eck N.J., Waltman L., VOSviewer Manual, (2023); van Eck N.J., Waltman L., Visualizing Bibliometric Networks, Measuring Scholarly Impact, pp. 285-320, (2014); Kumar S., Kumar S., Collaboration in Research Productivity in Oil Seed Research Institutes of India, Proceedings of the Fourth International Conference on Webometrics, Informetrics and Scientometrics & Ninth COLLNET Meeting, Humboldt-Universitat zu Berlin, Institute for Library and Information Science (IBI), pp. 1-18; Moral-Munoz J.A., Herrera-Viedma E., Santisteban-Espejo A., Cobo M.J., Software Tools for Conducting Bibliometric Analysis in Science: An up-to-Date Review, Prof. De La Inf, 29, (2020); Ricker M., Letter to the Editor: About the Quality and Impact of Scientific Articles, Scientometrics, 111, pp. 1851-1855, (2017)","K. Tsilika; School of Economics and Business, Department of Economics, Volos, 382 21, Greece; email: ktsilika@uth.gr","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","22277390","","","","English","Mathematics","Review","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85178375323" -"Ciric D.; Lalic B.; Marjanovic U.; Savkovic M.; Rakic S.","Ciric, Danijela (12758848000); Lalic, Bojan (35208507300); Marjanovic, Uglješa (55917669400); Savkovic, Milena (57266342300); Rakic, Slavko (57205509301)","12758848000; 35208507300; 55917669400; 57266342300; 57205509301","A Bibliometric Analysis Approach to Review Mass Customization Scientific Production","2021","IFIP Advances in Information and Communication Technology","634 IFIP","","","328","338","10","6","10.1007/978-3-030-85914-5_35","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115309873&doi=10.1007%2f978-3-030-85914-5_35&partnerID=40&md5=2c4c1f32e444cc635c467dacaef83f13","Faculty of Technical Sciences, University of Novi Sad, Novi Sad, 21000, Serbia","Ciric D., Faculty of Technical Sciences, University of Novi Sad, Novi Sad, 21000, Serbia; Lalic B., Faculty of Technical Sciences, University of Novi Sad, Novi Sad, 21000, Serbia; Marjanovic U., Faculty of Technical Sciences, University of Novi Sad, Novi Sad, 21000, Serbia; Savkovic M., Faculty of Technical Sciences, University of Novi Sad, Novi Sad, 21000, Serbia; Rakic S., Faculty of Technical Sciences, University of Novi Sad, Novi Sad, 21000, Serbia","Mass customization is an important manufacturing concept aimed at integrating product varieties to provide customized services and products based on individual needs. This concept has emerged in the 1980s as demand for product variety increased, and the research in this area has been present for the last three decades. This article aims to study the scientific production around mass customization through metadata analysis of all articles indexed in the bibliographic database Web of Science. The science mapping and bibliometric analysis was conducted using the “bibliometrix” R Package. Also, a graphical analysis of the bibliographic data was performed using VOSviewer software. This study identified the most relevant sources, authors, and countries active and influential through a five-stage workflow consisting of study design, data collection, data analysis, data visualization, and data interpretation. Keyword analysis revealed the related emerging research topics. Co-citation and co-occurrence analysis was performed to underline research streams. © 2021, IFIP International Federation for Information Processing.","Bibliometric analysis; Bibliometrix; Mass customization","Bibliographies; Data acquisition; Data visualization; Information services; Analysis approach; Bibliographic database; Bibliometrics analysis; Bibliometrix; Customized products; Customized services; Manufacturing concepts; Mass customization; Metadata analysis; Product variety; Computer aided manufacturing","","","","","National Natural Science Foundation of China, NSFC","Table 2 shows the top ten most productive countries with the total citations (TC) per country and average citations per article (AC). It could be observed that China is the country whose authors have published most articles, and the USA is second. When analyzing the number of total citations per country, the situation is reversed, with an average citation of 18.09 per article for the USA and 13.94 for China. It is important to highlight that England has the highest average citations per article (23.67) among the leading countries, which can be used as a proxy for scientific importance or article quality. When analyzing the funding sources in articles, it was identified that the National Natural Science Foundation of China NSFC is the funding agency with the highest occurrence in articles (76 articles). It could be noted that China is highly influential and dedicated to research in this field. Table 3 shows the most productive authors in mass customization research. This classification is based on the number of publications and the author’s h-index, which is calculated for this bibliographic collection. When comparing the number of articles produced with the production year start and the h-index for this bibliographic collection, it could be seen that Zhang M and Huang GQ are the two most influential authors. Forza C is the most productive author with 21 articles. According to co-authorship analysis among countries (Fig. 2), the most intensive collaboration exists among the USA, China, and England.","Ciric D., Lolic T., Gracanin D., Stefanovic D., Lalic B., The application of ICT solutions in manufacturing companies in Serbia, APMS 2020. IAICT, Vol. 592, pp. 122-129, (2020); Zawadzki P., Zywicki K., Smart product design and production control for effective mass customization in the industry 4.0 concept, Manage. Prod. Eng. Rev., 7, 3, pp. 105-112, (2016); Pine I.I., B.: Mass Customization: The New Frontier in Business Competition. Harvard Business School Press, Boston, (1993); da Silveira G., Borenstein D., Fogliatto H.S., Mass customization: Literature review and research directions, Int. J. Prod. Econ., 72, 49, pp. 1-13, (2001); Merediz-Sola I., Bariviera A.F., Research in international business and finance a bibliometric analysis of bitcoin scientific production, Res. Int. Bus. Financ., 50, pp. 294-305, (2019); Mongeon P., Paul-Hus A., The journal coverage of Web of Science and Scopus, Scientometrics, 106, 1, pp. 213-228, (2015); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, 3, pp. 1809-1831, (2015); Echchakoui S., Barka N., Industry 4.0 and its impact in plastics industry: A literature review, J. Ind. Inf. Integr., 20, (2020); Jin R., Yuan H., Chen Q., Resources, conservation & recycling science mapping approach to assisting the review of construction and demolition waste management research published between 2009 and 2018. Resour. Conserv, Recycl, 140, pp. 175-188, (2019); Alon I., Anderson J., Munim Z.H., Ho A., A review of the internationalization of Chinese enterprises, Asia Pac. J. Manage., 35, 3, pp. 573-605, (2018); Bashir M.F., Komal B.B., Bashir M.A., Analysis of environmental taxes publications: A bibliometric and systematic literature review, Environ. Sci. Pollut. Res., 28, pp. 20700-20716, (2021); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informet., 11, 4, pp. 959-975, (2017); Jan N., Ludo V.E., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Zupic I., Catez T., Bibliometric methods in management and organization, Organ. Res. Meth., 18, 3, pp. 429-472, (2015); Strozzi F., Colicchia C., Creazza A., Noe C., Literature review on the ‘smart factory’ concept using bibliometric tools, Int. J. Prod. Res., 55, 22, pp. 6572-6591, (2017)","D. Ciric; Faculty of Technical Sciences, University of Novi Sad, Novi Sad, 21000, Serbia; email: danijela.ciric@uns.ac.rs","Dolgui A.; Bernard A.; Lemoine D.; von Cieminski G.; Romero D.","Springer Science and Business Media Deutschland GmbH","","IFIP WG 5.7 International Conference on Advances in Production Management Systems, APMS 2021","5 September 2021 through 9 September 2021","Nantes","264779","18684238","978-303085913-8","","","English","IFIP Advances in Information and Communication Technology","Conference paper","Final","","Scopus","2-s2.0-85115309873" -"Kashani A.T.; Mirhashemi A.; Amirifar S.","Kashani, Ali Tavakoli (55070928500); Mirhashemi, Ali (57738376100); Amirifar, Saeideh (36117715000)","55070928500; 57738376100; 36117715000","A Review on Intersection Safety Studies with Bibliometric Methods","2022","Amirkabir Journal of Civil Engineering","54","5","","1811","1834","23","0","10.22060/ceej.2021.19921.7286","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85215298556&doi=10.22060%2fceej.2021.19921.7286&partnerID=40&md5=d4c1eb0a82db715e7315f81cf30924a1","Iran University of Science and Technology, Tehran, Iran","Kashani A.T., Iran University of Science and Technology, Tehran, Iran; Mirhashemi A., Iran University of Science and Technology, Tehran, Iran; Amirifar S., Iran University of Science and Technology, Tehran, Iran","Considering the increase in intersection safety studies, the present study will review these studies using scientometric methods. To this aim, 744 articles related to intersection safety until April 1, 2021, were extracted from the Web of Science (WOS) research engine. In the current study, co-citation, co-author, and co-occurrence of words were presented with descriptive analysis methods using VOS viewer and Bibliometrix software, which provide a descriptive, social, and conceptual framework, respectively. Also, the growth and development of the publications, the most cited articles, the most influential authors, sources, institutions, and countries are analyzed. Results showed that according to the co-citation analysis, the conceptual structure of intersection safety is divided into five main clusters: accident frequency, accident severity, safety performance measures, safety of vulnerable users, estimation of safety level, and intersection accident data analysis studies. Moreover, using conceptual analysis of keywords in intersection safety articles, topics related to cyclist safety, intelligent transportation systems, driver simulation, driver behavior, segment analysis, and road intersections were identified as high density and high centrality in studies. Topics such as empirical Bayes, resource allocation, vehicle communication, automated safety analysis, countermeasures, old drivers, and intersections without traffic lights were identified as basic and transversal themes. © 2022, Amirkabir University of Technology. All rights reserved.","Bibliometrics; Crash; Intersection safety; Review; Science mapping","","","","","","","","Tavakoli Kashani A., Ahmadi Nezhad A., Afshar A., Evaluating the Effects of Countdown Timers on Intersection Safety: A Case Study in Arak, Iran, AUT Journal of Civil Engineering, (2019); Tavakoli Kashani A., Amirifar S., Mirhashemi A., Investigating the impact of driver and vehicle characteristics on the risk of red-light running crashes, Amirkabir Journal of Civil Engineering, (2021); Iranian Legal Medicine Organization, (2020); About Intersection Safety, (2021); Johnson R., Watkinson A., Mabe M., The STM report, An overview of scientific and scholarly publishing, (2018); Diodato V.P., Gellatly P., Dictionary of Bibliometrics, (1994); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015); Cobo M.J., Chiclana F., Collop A., Ona J.d., Herrera- Viedma E., A Bibliometric Analysis of the Intelligent Transportation Systems Research Based on Science Mapping, IEEE Transactions on Intelligent Transportation Systems, 15, (2013); Gandia R.M., Antonialli F., Cavazza B.H., Neto A.M., Lima D.A.D., Sugano J.Y., Nicolai I., Zambalde A.L., Autonomous vehicles: Scientometric and bibliometric review, Transport Reviews, 39, 1, pp. 9-28, (2019); Zou X., Yue W.L., Vu H.L., Visualization and analysis of mapping knowledge domain of road safety studies, Accident Analysis and Prevention, 118, pp. 131-145, (2018); Ospina-Mateus H., Jimenez L.A.Q., Lopez-Valdes F.J., Salas-Navarro K., Bibliometric analysis in motorcycle accident research: A global overview, Scientometrics, 121, 2, pp. 793-815, (2019); van Nunen K., Li J., Reniers G., Ponnet K., Bibliometric analysis of safety culture research, Safety Science, 108, pp. 248-258, (2018); Cobo M.J., Chiclana F., Collop A., De Ona J., Herrera-Viedma E., A bibliometric analysis of the intelligent transportation systems research based on science mapping, IEEE Trans. Intell. Transp. Syst, 15, 2, pp. 901-908, (2014); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, J. Inf, 11, 4, pp. 959-975, (2017); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Nakagawa S., Samarasinghe G., Haddaway N.R., Westgate M.J., O'Dea R.E., Noble D.W.A., Lagisz M., Research Weaving: Visualizing the Future of Research Synthesis, Trends Ecol. Evol, 34, 3, pp. 224-238, (2019); Brookes B.C., Theory of the Bradford law, Journal of documentation, (1977); Neal W.O., Paddock W.A., Submission of Issues in Uncontrolled-Intersection Collision Cases in Texas-- Including a Related Discussion of Some Recent Trends in the Negligence Per Se Doctrine, Tex. L. Rev, 44, (1965); Lee C., Abdel-Aty M., Comprehensive analysis of vehicle–pedestrian crashes at intersections in Florida, Accident Analysis & Prevention, 37, 4, pp. 775-786, (2005); Poch M., Mannering F., Negative binomial analysis of intersection-accident frequencies, Journal of transportation engineering, 122, 2, pp. 105-113, (1996); Hafner M.R., Cunningham D., Caminiti L., Del Vecchio D., Cooperative collision avoidance at intersections: Algorithms and experiments, IEEE Trans. Intell. Transp. Syst, 14, 3, pp. 1162-1175, (2013); Adedokun A., Application of Road Infrastructure Safety Assessment Methods at Intersections, (2016); Reurings M.J., Eenink T., Elvik R., Cardoso R., Stefan C., Accident prediction models and road safety impact assessment: A state-of-the-art. Report D 2.1 of the RiPCORD-iSEREST project (Road Infrastructure Safety Protection-Core-Research and Development for Road Safety in Europe; Increasing safety and reliability of secondary roads for a sustainable Surface Transport), (2007); Lord D., Mannering F., The statistical analysis of crash-frequency data: A review and assessment of methodological alternatives, Transportation Research Part A: Policy and Practice, 44, 5, pp. 291-305, (2010); Chin H.C., Quddus M.A., Applying the random effect negative binomial model to examine traffic accident occurrence at signalized intersections, Accident Analysis & Prevention, 35, 2, pp. 253-259, (2003); Abdel-Aty M.A., Radwan A.E., Modeling traffic accident occurrence and involvement, Accident Analysis & Prevention, 32, 5, pp. 633-642, (2000); Wang X., Abdel-Aty M., Temporal and spatial analyses of rear-end crashes at signalized intersections, Accident Analysis & Prevention, 38, 6, pp. 1137-1150, (2006); Shankar V., Mannering F., Barfield W., Effect of roadway geometrics and environmental factors on rural freeway accident frequencies, Accident Analysis & Prevention, 27, 3, pp. 371-389, (1995); CROW, Road Safety Manual, (2009); Abdel-Aty M., Keller J., Exploring the overall and specific crash severity levels at signalized intersections, Accident Analysis & Prevention, 37, 3, pp. 417-425, (2005); Milton J.C., Shankar V.N., Mannering F.L., Highway accident severities and the mixed logit model: An exploratory empirical analysis, Accident Analysis & Prevention, 40, 1, pp. 260-266, (2008); Tay R., Rifaat S.M., Factors contributing to the severity of intersection crashes, Journal of Advanced Transportation, 41, 3, pp. 245-265, (2007); Persaud B.N., Retting R.A., Garder P.E., Lord D., Safety effect of roundabout conversions in the united states: Empirical bayes observational before-after study, Transportation Research Record, 1751, 1, pp. 1-8, (2001); Part D., Highway safety manual, (2010); Sayed T., Zein S., Traffic conflict standards for intersections, Transportation Planning and Technology, 22, 4, pp. 309-323, (1999); Gettman D., Head L., Surrogate safety measures from traffic simulation models, Transportation Research Record, 1840, 1, pp. 104-115, (2003); El-Basyouny K., Sayed T., Safety performance functions using traffic conflicts, Safety science, 51, 1, pp. 160-164, (2013); Khayesi M., The Handbook of Road Safety Measures, (2006); Mannering F.L., Bhat C.R., Analytic methods in accident research: Methodological frontier and future directions, Analytic methods in accident research, 1, pp. 1-22, (2014); Lord D., Washington S.P., Ivan J.N., Poisson, Poissongamma and zero-inflated regression models of motor vehicle crashes: Balancing statistical fit and theory, Accident Analysis & Prevention, 37, 1, pp. 35-46, (2005); Kim D.-G., Lee Y., Washington S., Choi K., Modeling crash outcome probabilities at rural intersections: Application of hierarchical binomial logistic models, Accident Analysis & Prevention, 39, 1, pp. 125-134, (2007); Yan X., Radwan E., Abdel-Aty M., Characteristics of rear-end accidents at signalized intersections using multiple logistic regression model, Accident Analysis & Prevention, 37, 6, pp. 983-995, (2005); Spiegelhalter D.J., Best N.G., Carlin B.P., Van Der Linde A., Bayesian measures of model complexity and fit, Journal of the royal statistical society: Series b (statistical methodology), 64, 4, pp. 583-639, (2002); Hauer E., Harwood D.W., Council F.M., Griffith M.S., Estimating safety by the empirical Bayes method: A tutorial, Transportation Research Record, 1784, 1, pp. 126-131, (2002); Ziakopoulos A., Yannis G., A review of spatial approaches in road safety, Accident Analysis & Prevention, 135, (2020); Hoffman T., Innovative approach in road infrastructure safety management and road impact assessment, (2014); Pei Y., Fu C., Investigating crash injury severity at unsignalized intersections in Heilongjiang Province, China, Journal of traffic and transportation engineering (English edition), 1, 4, pp. 272-279, (2014); Haleem K., Abdel-Aty M., Examining traffic crash injury severity at unsignalized intersections, Journal of safety research, 41, 4, pp. 347-357, (2010); Obeng K., Gender differences in injury severity risks in crashes at signalized intersections, Accident Analysis & Prevention, 43, 4, pp. 1521-1531, (2011); Abdelwahab H.T., Abdel-Aty M.A., Development of artificial neural network models to predict driver injury severity in traffic accidents at signalized intersections, Transportation Research Record, 1746, 1, pp. 6-13, (2001); Daniels S., Brijs T., Nuyts E., Wets G., Externality of risk and crash severity at roundabouts, Accident Analysis & Prevention, 42, 6, pp. 1966-1973, (2010); Daniels S., Brijs T., Nuyts E., Wets G., Injury crashes with bicyclists at roundabouts: Influence of some location characteristics and the design of cycle facilities, Journal of safety research, 40, 2, pp. 141-148, (2009); Elvik R., Effects on road safety of converting intersections to roundabouts: Review of evidence from non-US studies, Transportation Research Record, 1847, 1, pp. 1-10, (2003); Hao W., Daniel J., Motor vehicle driver injury severity study under various traffic control at highway-rail grade crossings in the United States, Journal of safety research, 51, pp. 41-48, (2014); Hao W., Kamga C., The effects of lighting on driver’s injury severity at highway-rail grade crossings, Journal of advanced transportation, 50, 4, pp. 446-458, (2016); Global status report on road safety 2018, (2019); Leden L., Pedestrian risk decrease with pedestrian flow. A case study based on data from signalized intersections in Hamilton, Ontario, Accident Analysis & Prevention, 34, 4, pp. 457-464, (2002); Pulugurtha S.S., Sambhara V.R., Pedestrian crash estimation models for signalized intersections, Accident Analysis & Prevention, 43, 1, pp. 439-446, (2011); Jacobsen P.L., Safety in numbers: More walkers and bicyclists, safer walking and bicycling, Injury prevention, 21, 4, pp. 271-275, (2015); Eluru N., Bhat C.R., Hensher D.A., A mixed generalized ordered response model for examining pedestrian and bicyclist injury severity level in traffic crashes, Accident Analysis & Prevention, 40, 3, pp. 1033-1054, (2008)","A.T. Kashani; Iran University of Science and Technology, Tehran, Iran; email: alitavakoli@iust.ac.ir","","Amirkabir University of Technology","","","","","","2588297X","","","","Persian","Amirkabir. J. Civ. Eng.","Review","Final","","Scopus","2-s2.0-85215298556" -"Tavassoli A.; Gharejedaghi S.M.; Abedi M.; Jamali S.M.; Ebrahim N.A.","Tavassoli, Afsaneh (57202001622); Gharejedaghi, Sara Modares (57660074200); Abedi, Maliheh (57660697200); Jamali, Seyedh Mahboobeh (57216965420); Ebrahim, Nader Ale (22974706300)","57202001622; 57660074200; 57660697200; 57216965420; 22974706300","Secondhand Smoking and the Fetus: A Bibliometric Analysis","2023","Medical Journal of the Islamic Republic of Iran","37","1","135","","","","2","10.47176/mjiri.37.135","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85184780710&doi=10.47176%2fmjiri.37.135&partnerID=40&md5=a3fb73ecbda0a314c46d671a28554b37","Department of Women and Family Studies, Faculty of Social Sciences and Economics, Alzahra University, Tehran, Iran; Department Business Administration, Faculty of Business and Economics, Eastern Mediterranean University, Famagusta, Cyprus; Department of Sociology, Payame Noor University (PNU), Tehran, Iran; Eshragh Institute, Ministry of Education, District 7, Tehran, Iran; Alzahra University, Tehran, Iran","Tavassoli A., Department of Women and Family Studies, Faculty of Social Sciences and Economics, Alzahra University, Tehran, Iran; Gharejedaghi S.M., Department Business Administration, Faculty of Business and Economics, Eastern Mediterranean University, Famagusta, Cyprus; Abedi M., Department of Sociology, Payame Noor University (PNU), Tehran, Iran; Jamali S.M., Eshragh Institute, Ministry of Education, District 7, Tehran, Iran; Ebrahim N.A., Alzahra University, Tehran, Iran","Background: Bibliometric analysis may indicate the most active specialist, authors, and journals in a given research field. To the authors' knowledge, there is no bibliometric analysis to provide a macroscopic overview in the field of secondhand smoke that harms non-smoker. Methods: Using the bibliometric method, 644 articles that were present in the Scopus database between 1973-2020 on the subject were considered. The data were analyzed by two visualization and science-mapping software called Bibliometrix and VoS Viewer. Also, reference publication year stereoscopy and Co-Citation historiography were used. In the qualitative analysis, 52 articles were selected that had the most citation and were analyzed. Results: In this paper, the findings show that the documents were published in 364 sources with an average citation per document of 25.14 and more than 3 authors or nearly 4 authors per document. The peak reference publication year stereoscopy happened in the year 199 with 974 references. The countries with the highest number of MCP were the USA, China, and Spain. The “International Journal of Environmental Research” and “Public Health”, has raised their publications in the field of secondhand smoke and pregnancy rapidly since 2003. Among the titles, ""passive smoking"" was the most used. Conclusion: The study highlights the importance of understanding the harmful effects of secondhand smoke on the developing fetus. The findings also shed light on key research trends, influential authors, and active research areas, which can guide future studies and support evidence-based decision-making in the field of maternal and child health. © Copyright Iran University of Medical Sciences","Bibliometric; Environmental smoke; Fetus; Health; Pregnancy; Secondhand smoking; Tobacco","","","","","","","","World Health Organization, (2020); Kuntz B, Zeiher J, Starker A, Lampert T., Smoking and secondhand smoke exposure among children and adolescents in Germany – Where do we stand today?, Atemwegs- und Lungenkrankheiten, 45, 5, pp. 217-226, (2019); Miller T, Rauh VA, Glied SAM, Hattis D, Rundle A, Andrews H, Et al., The economic impact of early life environmental tobacco smoke exposure: Early intervention for developmental delay, Environ Health Perspect, 114, 10, pp. 1585-1588, (2006); Naiman A, phD RM., Association of anti-smoking iegislation with rates of hospital admission for cardiovascular and respiratory conditions, RESEARCH, (2010); Choi KY, Yang SI, Lee E, Kim HB, Jung YH, Seo JH, Et al., Prenatal Second-Hand Smoke Increases Atopic Dermatitis in Children with TNF-α/TLR4/GSTP1 Polymorphisms, J Pediatr, 30, 1, pp. 18-25, (2017); Wang L, Zou Y, Wu P, Meng J, Zhang R., Phthalate exposure in pregnant women and the influence of exposure to environmental tobacco smoke, J Matern-Fetal Neonatal Med, (2019); A preliminary reportt on cigarette smoking and the incidence of prematurity, Obstet Gynecol Int, (1957); The presence of pets and smoking ascorrelates of perceived disease, J Allergy Clin Immunol, pp. 12-15, (1967); Samet JM, Lange P., Longitudinal Studies of Active and Passive Smoking, Am J Respir Crit, 154, 6, pp. S257-S65, (1996); Harris JK, Luke DA, Zuckerman RB, Shelton SC., Forty Years of Secondhand Smoke Research. The Gap Between Discovery and Delivery, Am J Prev Med, 36, 6, pp. 538-548, (2009); Ghanbari Baghestan A, Khaniki H, Kalantari A, Akhtari-Zavare M, Farahmand E, Tamam E, Et al., A Crisis in “Open Access”: Should Communication Scholarly Outputs Take 77 Years to Become Open Access?, SAGE Open, 9, 3, (2019); Ale Ebrahim S, Poshtan J, Jamali SM, Ale Ebrahim N., Quantitative and Qualitative Analysis of Time-Series Classification using Deep Learning, IEEE Access, 8, pp. 90202-90215, (2020); Nordin N, Samsudin MA, Abdul-Khalid SN, Ale Ebrahim N., Firms’ sustainable practice research in developing countries: Mapping the cited literature by Bibliometric analysis approach, IJSSM, 7, 1, (2019); Yusop FD, Ghaffar FA, Danaee M, Firdaus A, Hamzaid NA, Hassan ZFA, Et al., Two decades of research on early career faculties (ECFs): a bibliometric analysis of trends across regions, JSSH, 28, 1, pp. 325-342, (2020); Aghaei Chadegani A, Salehi H, Yunus MM, Farhadi H, Fooladi M, Farhadi M, Et al., A Comparison between Two Main Academic Literature Collections: Web of Science and Scopus Databases, Asian Soc Sci, 9, 5, pp. 18-26, (2013); Ale Ebrahim S, Ashtari A, Pedram MZ, Ebrahim NA, Sanati-Nezhad A., Publication Trends in Exosomes Nanoparticles for Cancer Detection, Int J Nanomed, 15, (2020); Aghaei Chadegani A, Salehi H, Yunus M, Farhadi H, Fooladi M, Farhadi M, Et al., A comparison between two main academic literature collections: Web of Science and Scopus databases, Asian Soc Sci, 9, 5, pp. 18-26, (2013); Aria M, Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, J Informetr, 11, 4, pp. 959-975, (2017); Van Eck NJ, Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Khodabandelou R, Ale Ebrahim N, Amoozegar A, Mehran G., Revisiting Three Decades Of Educational Research In Iran: A Bibliometric Analysis, Iran. 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Public Health, 2, 1, pp. 1-21, (2019); Marx W, Bornmann L, Barth A, Leydesdorff L., Detecting the historical roots of research fields by reference publication year spectroscopy (RPYS), J Assoc Inf Sci, 65, 4, pp. 751-764, (2014); Rubin D, Leventhal J, Krasilnikoff P, Weile B, Berget A., EFFECT OF PASSIVE SMOKING ON BIRTH-WEIGHT, The Lancet, 328, 8504, pp. 415-417, (1986); Martin TR, Bracken MB., Association of low birth weight with passive smoke exposure in pregnancy, Am J Epidemiol, 124, 4, pp. 633-642, (1986); Windham GC, Eaton A, Hopkins B., Evidence for an association between environmental tobacco smoke exposure and birthweight: A meta-analysis and new data, Paediatr Perinat Epidemiol, 13, 1, pp. 35-57, (1999); Eskenazi B, Castorina R., Association of prenatal maternal or postnatal child environmental tobacco smoke exposure and neurodevelopmental and behavioral problems in children, Environ Health Perspect, 107, 12, pp. 991-1000, (1999); Leonardi-Bee J, Smyth A, Britton J, Coleman T., Environmental tobacco smoke and fetal health: Systematic review and meta-analysis, Arch Dis Child, 93, 5, pp. f351-f61, (2008); DiFranza JR, Aligne CA, Weitzman M., Prenatal and Postnatal Environmental Tobacco Smoke Exposure and Children's Health, Pediatrics, 113, 4, pp. 1007-1015, (2004); Slotkin TA, Pinkerton KE, Seidler FJ., Perinatal environmental tobacco smoke exposure in rhesus monkeys: Critical periods and regional selectivity for effects on brain cell development and lipid peroxidation, Environ Health Perspect, 114, 1, pp. 34-39, (2006); Gilliland FD, Li YF, Peters JM., Effects of maternal smoking during pregnancy and environmental tobacco smoke on asthma and wheezing in children, Am J Respir Crit, 163, 2, pp. 429-436, (2001); Florescu A, Ferrence R, Einarson T, Selby P, Soldin O, Koren G., Methods for quantification of exposure to cigarette smoking and environmental tobacco smoke: Focus on developmental toxicology, Ther Drug Monit, 31, 1, pp. 14-30, (2009); Gilliland FD, Li YF, Dubeau L, Berhane K, Avol E, McConnell R, Et al., Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children, Am J Respir Crit, 166, 4, pp. 457-463, (2002); Salmasi G, Grady R, Jones J, McDonald SD., Environmental tobacco smoke exposure and perinatal outcomes: a systematic review and metaanalyses, Acta Obstet Gynecol Scand, 89, 4, pp. 423-441, (2010); Herrmann M, King K, Weitzman M., Prenatal tobacco smoke and postnatal secondhand smoke exposure and child neurodevelopment, Curr Opin Pediatr, 20, 2, pp. 184-190, (2008); Qiu J, He X, Cui H, Zhang C, Zhang H, Dang Y, Et al., Passive smoking and preterm birth in urban China, Obstet Gynecol Surv, 69, 11, pp. 647-649, (2014); Gilliland FD, Berhane K, McConnell R, Gauderman WJ, Vora H, Rappaport EB, Et al., Maternal smoking during pregnancy, environmental tobacco smoke exposure and childhood lung function, Thorax, 55, 4, pp. 271-276, (2000); Honein MA, Rasmussen SA, Reefhuis J, Romitti PA, Lammer EJ, Sun L, Et al., Maternal smoking and environmental tobacco smoke exposure and the risk of orofacial clefts, Epidemiology, 18, 2, pp. 226-233, (2007); Gergen PJ, Fowler JA, Maurer KR, Davis WW, Overpeck MD., The burden of environmental tobacco smoke exposure on the respiratory health of children 2 months through 5 years of age in the United States: Third National Health and Nutrition Examination Survey, 1988 to 1994, Pediatrics, 101, 2, (1998); Vardavas CI, Hohmann C, Patelarou E, Martinez D, Henderson AJ, Granell R, Et al., The independent role of prenatal and postnatal exposure to active and passive smoking on the development of early wheeze in children, Eur Respir J, 48, 1, pp. 115-124, (2016); Ward C, Lewis S, Coleman T., Prevalence of maternal smoking and environmental tobacco smoke exposure during pregnancy and impact on birth weight: Retrospective study using Millennium Cohort, BMC Public Health, 7, (2007); Cheraghi M, Salvi S., Environmental tobacco smoke (ETS) and respiratory health in children, Eur J Pediatr, 168, 8, pp. 897-905, (2009); Kabesch M, Hoefler C, Carr D, Leupold W, Weiland SK, Von Mutius E., Glutathione S transferase deficiency and passive smoking increase childhood asthma, Thorax, 59, 7, pp. 569-573, (2004); Anderson HR, Cook DG., Passive smoking and sudden infant death syndrome: Review of the epidemiological evidence, Thorax, 52, 11, pp. 1003-1009, (1997); Bandiera FC, Kalaydjian Richardson A, Lee DJ, He JP, Merikangas KR., Secondhand smoke exposure and mental health among children and adolescents, Arch Pediatr Adolesc Med, 165, 4, pp. 332-338, (2011); Bloch M, Althabe F, Onyamboko M, Kaseba-Sata C, Castilla EE, Freire S, Et al., Tobacco use and secondhand smoke exposure during pregnancy: An investigative survey of women in 9 developing nations, Am J Public Health, 98, 10, pp. 1833-1840, (2008); Husgafvel-Pursiainen K., Genotoxicity of environmental tobacco smoke: A review, Mutat Res, 567, 2-3, pp. 427-445, (2004); Tsai CH, Huang JH, Hwang BF, Lee YL., Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among children in Taiwan, Respir Res, 11, (2010); Hull MGR, North K, Taylorb H, Farrow A, Christopher L, Ford W., Delayed conception and active and passive smoking, Fertil Steril, 74, 4, pp. 725-733, (2000); Chen ZY, Li J, Huang GY., Effect of bushen yiqi huoxue recipe on placental vasculature in pregnant rats with fetal growth restriction induced by passive smoking, J Huazhong Univ Sci, 33, 2, pp. 293-302, (2013); Rauh VA, Whyatt RM, Garfinkel R, Andrews H, Hoepner L, Reyes A, Et al., Developmental effects of exposure to environmental tobacco smoke and material hardship among inner-city children, Neurotoxicol Teratol, 26, 3, pp. 373-385, (2004); Vanker A, Gie RP, Zar HJ., Early-life exposures to environmental tobacco smoke and indoor air pollution in the drakenstein child health study: Impact on child health, S Afr Med J, 108, 2, pp. 71-72, (2018); Collaco JM, Vanscoy L, Bremer L, McDougal K, Blackman SM, Bowers A, Et al., Interactions between secondhand smoke and genes that affect cystic fibrosis lung disease, JAMA, 299, 4, pp. 417-424, (2008); Steyn K, De Wet T, Saloojee Y, Nel H, Yach D., The influence of maternal cigarette smoking, snuff use and passive smoking on pregnancy outcomes: The Birth to Ten Study, Paediatr Perinat Epidemiol, 20, 2, pp. 90-99, (2006); Boffetta P, Tredaniel J, Greco A., Risk of childhood cancer and adult lung cancer after childhood exposure to passive smoke: A metaanalysis, Environ Health Perspect, 108, 1, pp. 73-82, (2000); Kum-Nji P, Meloy L, Herrod HG., Environmental tobacco smoke exposure: Prevalence and mechanisms of causation of infections in children, Pediatrics, 117, 5, pp. 1745-1754, (2006); Lannero E, Wickman M, Van Hage M, Bergstrom A, Pershagen G, Nordvall L., Exposure to environmental tobacco smoke and sensitisation in children, Thorax, 63, 2, pp. 172-176, (2008); Kharrazi M, DeLorenze GN, Kaufman FL, Eskenazi B, Bernert JT, Graham S, Et al., Environmental tobacco smoke and pregnancy outcome, Epidemiology, 15, 6, pp. 660-670, (2004); Zhou S, Rosenthal DG, Sherman S, Zelikoff J, Gordon T, Weitzman M., Physical, behavioral, and cognitive effects of prenatal tobacco and postnatal secondhand smoke exposure, Curr Probl Pediatr Adolesc Health Care, 44, 8, pp. 219-241, (2014); Dixit S, Pletcher MJ, Vittinghoff E, Imburgia K, Maguire C, Whitman IR, Et al., Secondhand smoke and atrial fibrillation: Data from the Health eHeart Study, Heart Rhythm, 13, 1, pp. 3-9, (2016); Sabbagh HJ, Hassan MHA, Innes NPT, Elkodary HM, Little J, Mossey PA., Passive smoking in the etiology of non-syndromic orofacial clefts: A systematic review and meta-analysis, PLoS ONE, 10, 3, (2015); George L, Granath F, Johansson ALV, Anneren G, Cnattingius S., Environmental tobacco smoke and risk of spontaneous abortion, Epidemiology, 17, 5, pp. 500-505, (2006); Fantuzzi G, Aggazzotti G, Righi E, Facchinetti F, Bertucci E, Kanitz S, Et al., Preterm delivery and exposure to active and passive smoking during pregnancy: A case-control study from Italy, Paediatr Perinat Epidemiol, 21, 3, pp. 194-200, (2007); Hyland A, Piazza KM, Hovey KM, Ockene JK, Andrews CA, Rivard C, Et al., Associations of lifetime active and passive smoking with spontaneous abortion, stillbirth and tubal ectopic pregnancy: A crosssectional analysis of historical data from the women's health initiative, Tob Control, 24, 4, pp. 328-335, (2015); Rosa MJ, Jung KH, Perzanowski MS, Kelvin EA, Darling KW, Camann DE, Et al., Prenatal exposure to polycyclic aromatic hydrocarbons, environmental tobacco smoke and asthma, Respir Med, 105, 6, pp. 869-876, (2011); Pagani LS., Environmental tobacco smoke exposure and brain development: The case of attention deficit/hyperactivity disorder, Neurosci Biobehav Rev, 44, pp. 195-205, (2014); Lee M, Ha M, Hong YC, Park H, Kim Y, Kim EJ, Et al., Exposure to prenatal secondhand smoke and early neurodevelopment: Mothers and Children's Environmental Health (MOCEH) study, Environ Health: Glob Access Sci, 18, 1, (2019); Yi O, Kwon HJ, Kim H, Ha M, Hong SJ, Hong YC, Et al., Effect of environmental tobacco smoke on atopic dermatitis among children in Korea, Environ Res, 113, pp. 40-45, (2012); Lam TH, Leung GM, Ho LM., The effects of environmental tobacco smoke on health services utilization in the first eighteen months of life, Pediatrics, 107, 6, (2001); Dejmek J, Solansky I, Podrazilova K, Sram RJ., The exposure of nonsmoking and smoking mothers to environmental tobacco smoke during different gestational phases and fetal growth, Environ Health Perspect, 110, 6, pp. 601-606, (2002); Simons E, To T, Moineddin R, Stieb D, Dell SD., Maternal secondhand smoke exposure in pregnancy is associated with childhood asthma development, J Allergy Clin Immunol, 2, 2, pp. 201-207, (2014); Murray RL, Britton J, Leonardi-Bee J., Second hand smoke exposure and the risk of invasive meningococcal disease in children: Systematic review and meta-analysis, BMC Public Health, 12, 1, (2012); Oh SS, Tcheurekdjian H, Roth LA, Nguyen EA, Sen S, Galanter JM, Et al., Effect of secondhand smoke on asthma control among black and Latino children, J Allergy Clin. Immunol, 129, 6, pp. 1478-1483, (2012); Jaakkola JJK, Jaakkola N, Zahlsen K., Fetal Growth and length of gestation in relation to prenatal exposure to environmental tobacco smoke assessed by hair nicotine concentration, Environ Health Perspect, 109, 6, pp. 557-561, (2001); Han JY, Kwon HJ, Ha M, Paik KC, Lim MH, Gyu Lee S, Et al., The effects of prenatal exposure to alcohol and environmental tobacco smoke on risk for ADHD: A large population-based study, Psychiatry Res, 225, 1-2, pp. 164-168, (2015); Gravetter Frederike J, Forzano B L-A., Reasergh Methods for the Behavioral Sciences2018; Leonardi-Bee J, Britton J, Venn A., Secondhand smoke and adverse fetal outcomes in nonsmoking pregnant women: A meta-analysis, Pediatrics, 127, 4, pp. 734-741, (2011); Yosefi J, Mirzade M, To study the prevance of LBW and to determinethe ratio preterm to IUGR during one year in 22 Bahman Hospital, Medicine sina, 5, (2015)","A. Tavassoli; Department of Women and Family Studies, Faculty of Social Sciences and Economics, Alzahra University, Tehran, Iran; email: afsaneh_tavassoli@alzahra.ac.ir","","Iran University of Medical Sciences","","","","","","10161430","","MJIIE","","English","Med. J. Islam. Repub. Iran","Article","Final","","Scopus","2-s2.0-85184780710" -"Xu D.; Xu Z.","Xu, Duo (57313041700); Xu, Zeshui (55502698400)","57313041700; 55502698400","Bibliometric analysis of decision-making in healthcare management from 1998 to 2021","2023","International Journal of Healthcare Management","16","4","","623","637","14","2","10.1080/20479700.2022.2134641","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140075486&doi=10.1080%2f20479700.2022.2134641&partnerID=40&md5=3007e5eccfd675f5d3be31087dc51efe","Business School, Stevens Institute of Technology, Hoboken, NJ, United States; Business School, Sichuan University, Chengdu, China","Xu D., Business School, Stevens Institute of Technology, Hoboken, NJ, United States; Xu Z., Business School, Sichuan University, Chengdu, China","Healthcare management (HCM) has attracted significant attention from scholars and practitioners, and decision-making (DM) is always perceived as a crucial managerial function. This paper attempts to explore the trend and structure of DM research in the field of HCM (DM-HCM) by conducting a bibliometric analysis of publications from 1998 to 2021. A total of 581 documents covering all the available evidence are retrieved from the Web of Science (WoS) core collection. First, a descriptive performance analysis is performed based on widely accepted bibliometric indicators, followed by identifying primary contributors in the research community. Then, a science mapping analysis is implemented to discover the structural connections among different research constituents using three visualization tools, namely, VoS viewer, CiteSpace, and Bibliometrix. The citation-related and co-authorship networks are analyzed to explore the intellectual structure of the bibliometric corpus. Moreover, the keyword co-occurrence, timeline view, and evolution analysis enrich the understanding of thematic clusters and identify the DM-HCM research focus. Finally, the main findings are summarized, and possible research directions are proposed. © 2022 Informa UK Limited, trading as Taylor & Francis Group.","Bibliometric analysis; decision making; healthcare management","article; bibliometrics; decision making; health care management; human; Web of Science; writing","","","","","","","Buchbinder S.B., Shanks N.H., Kite B.J., Introduction to health care management, (2019); Thompson J.M., Understanding and managing organizational change, J Public Health Manag Pract, 16, 2, pp. 167-173, (2010); Morgan O., How decision makers can use quantitative approaches to guide outbreak responses, Philos Trans Royal Soci B Biol Sci, 374, 1776, (2019); Hashemkhani Zolfani S., Yazdani M., Ebadi Torkayesh A., Et al., Application of a gray-based decision support framework for location selection of a temporary hospital during COVID-19 pandemic, Sym (Basel), 12, 6, (2020); Asan O., Bayrak A.E., Choudhury A., Artificial intelligence and human trust in healthcare: focus on clinicians, J Med Internet Res, 22, 6, (2020); Galetsi P., Katsaliaki K., Kumar S., Big data analytics in health sector: theoretical framework, techniques and prospects, Int J Inf Manage, 50, pp. 206-216, (2020); Basile L.J., Carbonara N., Pellegrino R., Et al., Business intelligence in the healthcare industry: the utilization of a data-driven approach to support clinical decision making, Technovation, (2022); Akmal A., Greatbanks R., Foote J., Lean thinking in healthcare–Findings from a systematic literature network and bibliometric analysis, Health Policy, 124, 6, pp. 615-627, (2020); Guo Y., Hao Z., Zhao S., Et al., Artificial intelligence in health care: bibliometric analysis, J Med Internet Res, 22, 7, (2020); Ellis L.A., Churruca K., Clay-Williams R., Et al., Patterns of resilience: a scoping review and bibliometric analysis of resilient health care, Saf Sci, 118, pp. 241-257, (2019); Punnakitikashem P., Hallinger P., Bibliometric review of the knowledge base on healthcare management for sustainability, 1994–2018, Sustainability, 12, 1, (2020); Fusco F., Marsilio M., Guglielmetti C., Co-production in health policy and management: a comprehensive bibliometric review, BMC Health Serv Res, 20, 1, pp. 1-16, (2020); Lu C., Li X., Yang K., Trends in shared decision-making studies from 2009 to 2018: a bibliometric analysis, Front Public Health, 7, (2019); Alsalem M.A., Alamoodi A.H., Albahri O.S., Et al., Multi-criteria decision-making for coronavirus disease 2019 applications: a theoretical analysis review, Artif Intell Rev, 55, pp. 4979-5062, (2022); Martin-Martin A., Orduna-Malea E., Thelwall M., Et al., Google scholar, web of science, and Scopus: a systematic comparison of citations in 252 subject categories, J Informetr, 12, 4, pp. 1160-1177, (2018); Singh V.K., Singh P., Karmakar M., Et al., The journal coverage of web of science, Scopus and dimensions: a comparative analysis, Scientometrics, 126, 6, pp. 5113-5142, (2021); Boyack K.W., Klavans R., Co-citation analysis, bibliographic coupling, and direct citation: Which citation approach represents the research front most accurately?, J Am Soc Informat Sci Technol, 61, 12, pp. 2389-2404, (2010); Wong A.K.F., Koseoglu M.A., Kim S.S., The intellectual structure of corporate social responsibility research in tourism and hospitality: a citation/co-citation analysis, J Hosp Tourism Manag, 49, pp. 270-284, (2021); Donthu N., Kumar S., Mukherjee D., Et al., How to conduct a bibliometric analysis: an overview and guidelines, J Bus Res, 133, pp. 285-296, (2021); Wang X., Xu Z., Qin Y., Structure, trend and prospect of operational research: a scientific analysis for publications from 1952 to 2020 included in Web of Science database, Fuzzy Optim Decis Mak, (2022); Tahamtan I., Safipour Afshar A., Ahamdzadeh K., Factors affecting number of citations: a comprehensive review of the literature, Scientometrics, 107, 3, pp. 1195-1225, (2016); Van Eck N., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Chen C., CiteSpace II: Detecting and visualizing emerging trends and transient patterns in scientific literature, J Am Soc Informat Sci Technol, 57, 3, pp. 359-377, (2006); Aria M., Cuccurullo C., bibliometrix : An R-tool for comprehensive science mapping analysis, J Informetr, 11, 4, pp. 959-975, (2017); Nayak S., Behera D.K., Shetty J., Et al., Bibliometric analysis of scientific publications on health care insurance in India from 2000 to 2021, Int J Healthc Manag, (2022); Hirsch J.E., An index to quantify an individual’s scientific research output, Proce Nat Academy Sci, 102, 46, pp. 16569-16572, (2005); Saggi M.K., Jain S., A survey towards an integration of big data analytics to big insights for value-creation, Inf Process Manag, 54, 5, pp. 758-790, (2018); Abdel-Basset M., Manogaran G., Gamal A., Et al., A group decision making framework based on neutrosophic TOPSIS approach for smart medical device selection, J Med Syst, 43, 2, pp. 1-13, (2019); Ma N., Guan J., Zhao Y., Bringing PageRank to the citation analysis, Inf Process Manag, 44, 2, pp. 800-810, (2008); Li Y., Xu Z., Wang X., A bibliometric analysis on deep learning during 2007–2019, Int J Mach Learn Cyb, 11, 12, pp. 2807-2826, (2020); Ye N., Kueh T.B., Hou L., Et al., A bibliometric analysis of corporate social responsibility in sustainable development, J Clean Prod, 272, (2020); Wang X., Xu Z., Su S., Et al., A comprehensive bibliometric analysis of uncertain group decision making from 1980 to 2019, Informat Sci, 547, pp. 328-353, (2021)","Z. Xu; Business School, Sichuan University, Chengdu, No. 24 South Section 1 Yihuan Road, 610064, China; email: xuzeshui@263.net","","Taylor and Francis Ltd.","","","","","","20479700","","","","English","Int. J. Healthc. Manage.","Article","Final","","Scopus","2-s2.0-85140075486" -"Moral-Muñoz J.A.; Herrera-Viedma E.; Santisteban-Espejo A.; Cobo M.J.","Moral-Muñoz, José A. (56062277800); Herrera-Viedma, Enrique (7004240703); Santisteban-Espejo, Antonio (57202390364); Cobo, Manuel J. (25633455900)","56062277800; 7004240703; 57202390364; 25633455900","Software tools for conducting bibliometric analysis in science: An up-to-date review","2020","Profesional de la Informacion","29","1","e290103","","","","1103","10.3145/epi.2020.ene.03","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85082037610&doi=10.3145%2fepi.2020.ene.03&partnerID=40&md5=fbe1491b27133686664e17854a67d858","University of Cadiz, Institute of Research and Innovation in Biomedical Sciences of the Province of Cadiz (INiBICA), Cadiz, Spain; University of Granada, E.T.S. de Ingeniería Informática y de Telecomunicación, Periodista Daniel Saucedo Aranda, s/n, Granada, 18014, Spain; Puerta del Mar Hospital, Division of Hematology and Hemotherapy, Cadiz, Spain; University of Cadiz, Department of Computer Science and Engineering, Cadiz, Spain","Moral-Muñoz J.A., University of Cadiz, Institute of Research and Innovation in Biomedical Sciences of the Province of Cadiz (INiBICA), Cadiz, Spain; Herrera-Viedma E., University of Granada, E.T.S. de Ingeniería Informática y de Telecomunicación, Periodista Daniel Saucedo Aranda, s/n, Granada, 18014, Spain; Santisteban-Espejo A., Puerta del Mar Hospital, Division of Hematology and Hemotherapy, Cadiz, Spain; Cobo M.J., University of Cadiz, Department of Computer Science and Engineering, Cadiz, Spain","Bibliometrics has become an essential tool for assessing and analyzing the output of scientists, cooperation between universities, the effect of state-owned science funding on national research and development performance and educational efficiency, among other applications. Therefore, professionals and scientists need a range of theoretical and practical tools to measure experimental data. This review aims to provide an up-to-date review of the various tools available for conducting bibliometric and scientometric analyses, including the sources of data acquisition, performance analysis and visualization tools. The included tools were divided into three categories: general bibliometric and performance analysis, science mapping analysis, and libraries; a description of all of them is provided. A comparative analysis of the database sources support, pre-processing capabilities, analysis and visualization options were also provided in order to facilitate its understanding. Although there are numerous bibliometric databases to obtain data for bibliometric and scientometric analysis, they have been developed for a different purpose. The number of exportable records is between 500 and 50,000 and the coverage of the different science fields is unequal in each database. Concerning the analyzed tools, Bibliometrix contains the more extensive set of techniques and suitable for practitioners through Biblioshiny. VOSviewer has a fantastic visualization and is capable of loading and exporting information from many sources. SciMAT is the tool with a powerful pre-processing and export capability. In views of the variability of features, the users need to decide the desired analysis output and chose the option that better fits into their aims. © 2020, El Profesional de la Informacion. All rights reserved.","Bibliographic databases; Bibliometrics; Libraries; Performance analysis; Python-package; R-package; Science mapping analysis; Scientometrics; Software; Software review; Tools","","","","","","National Science Foundation, NSF; National Institutes of Health, NIH","- Sci2 Tool 圀 It is a modular toolset particularly intended to play out the research of science ?Sci2 Team 唀 缃堀 It supports temporal 唀 geospatial 唀 topical 唀 and network analysis and the representation of datasets at the micro 縁崁瘁ᨁ崁쀁崁ᨁ딁ȁ漃缃唀 meso 縁漁紁?al 缃唀 and macro ?global 缀 levels 堀 It wCaysbedreinvefrlaospterducbtuyre for Network Science Center at Indiana Uni- versity 縀栀SA 缃堀 It read several bibliographic data formats 唀WsouSc,hSacsopus, GS, Bitext and the exportation data format of EndNote 堀 Furthermore 唀 it can analyze data information from social media Flaikcebook 唀 research funding from the National Science Foundation and National Institutes of Health 唀 as well as other academic data in CSV format 堀 As can be observed 唀 this tool supports a wide variety of information sources 堀 STchi2eTool workflow is based on the typical science study ?Börner; Chen; Boyack 唀 缃圀 ?ata acquisition and processing 唀 ?ata analysis 唀 Modeling 唀 and Layout 堀 It allows extracting different types of networks 唀 performing several analyses 縁?emporal 唀 geospatial 唀 textual and networks 缃堀 Mainly 唀 this tool obtains the following bibliometric networks 圀 co 爁ȁ딁騁Ror 唀 co 爀圀I 縀圁谁崁瘁ခ崁褁ȁ漀 Investigator 缃唀 documents co 爁ခ崁?ation 唀 journals co 爁ခ崁?ation 唀 authors co 爁ခ崁?ation 唀 bibliographic coupling 唀 author bibliographic coupling and journals bibliographic coupling 堀 Likewise 唀 this tool allows building direct link networks 唀 such as author 爁?eferen-ces 唀 document 爁?eferences 唀 journals 爁?eferences and author 爁ᨁ紁ခ?ments networks 堀 In order to represent the networks obtained 唀 different visualization can be obtained 圀 i 缀 Temporal visualization 唀 ii 缀 Geospatial visualization 唀 iii 缀 Choropleth map 唀 iv 缀 ?roportional symbol map 唀 v 缀 Topical visualization 唀 and vi 缀 Network visualization 堀 This tool offers a great and adequate number of possibilities in order to represent the different aspects of science 堀","Sergio A., Francisco-Javier C., Enrique H.-V., Francisco H., H-index: A review focused in its variants, computation and standardization for different scientific fields, Journal of Informetrics, 3, 4, pp. 273-289, (2009); Alonso S., Cabrerizo F.-J., Herrera-Viedma E., Herrera F., Hg-index: A new index to characterize the scientific output of researchers based on the h-and g-indices, Scientometrics, 82, 2, pp. 391-400, (2010); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Asimov I., A Short History of Chemistry-An Introduction to the Ideas and Concepts of Chemistry, (2010); Batagelj V., Mrvar A., Pajek-Analysis and visualization of large networks, Graph Drawing Software SE, 4, pp. 77-103, (2004); Borgatti S.P., Everett M.G., Freeman L.C., Ucinet 6 for Windows: Software for Social Network analysis”, (2002); Katy B., Chaomei C., Boyack K.W., Visualizing knowledge domains”. 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An empirical example from evaluative institutional bibliometrics using adjusted predictions and marginal effects, Journal of Informetrics, 7, 2, pp. 562-574, (2013); Michael B., Vadim O., Jeffrey H., D3 Data-driven documents, IEEE Transactions on Visualization and Computer Graphics, 17, 12, pp. 2301-2309, (2011); Francisco-Javier C., Sergio A., Enrique H.-V., Francisco H., Q2-Index: Quantitative and qualitative evaluation based on the number and impact of papers in the Hirsch core, Journal of Informetrics, 4, 1, pp. 23-28, (2010); Chapman K., Ellinger A.E., An evaluation of Web of Science, Scopus and Google Scholar citations in operations management, International Journal of Logistics Management, 30, 4, pp. 1039-1053, (2019); Chen C., CiteSpace II: Detecting and visualizing emerging trends and transient patterns in scientific lite-rature, Journal of the American Society for Information Science and Technology, 57, pp. 359-377, (2006); Chen C., Science mapping: A systematic review of the literature, Journal of Data and Information Science, 2, 2, pp. 1-40, (2017); Chaomei C., How to Use Citespace, (2019); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: A practical application to the fuzzy sets theory field, Journal of Informetrics, 5, 1, pp. 146-166, (2011); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., SciMAT: A new science mapping analysis software tool, Journal of the American Society for Information Science and Technology, 63, 8, pp. 1609-1630, (2012); Egghe L., Theory and practise of the g-index, Scientometrics, 69, pp. 131-152, (2006); Ellegaard O., Wallin J.A., The bibliometric analysis of scholarly production: How great is the impact?, Scientometrics, 105, pp. 1809-1831, (2015); Fabregat-Aibar L., Barbera-Marine M.G., Terceno A., Pie L., A bibliometric and visualization analysis of socially responsible funds, Sustainability, 11, 9, (2019); Gagolewski M., Bibliometric impact assessment with R and the Citan package, Journal of Informetrics, 5, 4, pp. 678-692, (2011); Eugene G., Pudovkin A.I., Istomin V.S., Why do we need algorithmic historiography?, Journal of the American Society for Information Science and Technology, 54, 5, pp. 400-412, (2003); Glanzel W., Bibliometric methods for detecting and analysing emerging research topics, El Profesional De La información, 21, 2, pp. 194-201, (2012); Grauwin S., Jensen P., Mapping scientific institutions, Scientometrics, 89, (2011); Gusenbauer M., Google Scholar to overshadow them all? Comparing the sizes of 12 academic search engines and bibliographic databases, Scientometrics, 118, pp. 177-214, (2019); Gutierrez-Salcedo M., Martinez M.A., Moral-Munoz J.A., Herrera-Viedma E., Cobo M.J., Some bibliometric procedures for analyzing and evaluating research fields, Applied Intelligence, 48, 5, pp. 1275-1287, (2018); Anne-Wil H., Reflections on the h-index”, (2008); Harzing A.-W., Alakangas S., Microsoft Academic: Is the phoenix getting wings?, Scientometrics, 110, 1, pp. 371-383, (2017); Harzing A.-W.K., Ron V.D.-W., Google Scholar as a new source for citation analysis, Ethics in Science and Environmental Politics, 8, 1, pp. 61-73, (2008); Haunschild R., Hug S.E., Brandle M.P., Bornmann L., The number of linked references of publications in Microsoft Academic in comparison with the Web of Science, Scientometrics, 114, pp. 367-370, (2018); Hirsch J.E., An index to quantify an individual’s scientific research output”, Proceedings of the National Academy of Sciences of the United States of America, 102, 46, pp. 16569-16572, (2005); Hug S.E., Ochsner M., Brandle M.P., Citation analysis with Microsoft Academic, Scientometrics, 111, pp. 371-378, (2017); Ibba S., Pani F.-E., Stockton J.-G., Barabino G., Marchesi M., Tigano D., Incidence of predatory journals in computer science literature, Library Review, 66, 6-7, pp. 505-522, (2017); Martin-Martin A., Orduna-Malea E., Delgado-Lopez-Cozar E., Coverage of highly-cited documents in Google Scholar, Web of Science, and Scopus: A multidisciplinary comparison, Scientometrics, 116, pp. 2175-2188, (2018); Martin-Martin A., Orduna-Malea E., Harzing A.-W., Delgado-Lopez-Cozar E., Can we use Google Scholar to identify highly-cited documents?, Journal of Informetrics, 11, 1, pp. 152-163, (2017); Marx W., Bornmann L., Barth A., Leydesdorff L., Detecting the historical roots of research fields by reference publication year spectroscopy (RPYS), Journal of the Association for Information Science and Technology, 65, 4, pp. 751-764, (2014); McLevey J., McIlroy-Young R., Introducing metaknowledge: Software for computational research in information science, network analysis, and science of science, Journal of Informetrics, 11, 1, pp. 176-197, (2017); Mongeon P., Paul-Hus A., The journal coverage of Web of Science and Scopus: A comparative analy-sis, Scientometrics, 106, pp. 213-228, (2016); Moral-Munoz J.A., Lopez-Herrera A.G., Enrique H.-V., Cobo M.J., Science mapping analysis software tools: A review, Springer Handbook of Science and Technology Indicators, pp. 159-185, (2019); Francis N., Hamilton K.S., Bibliometric performance measures, Scientometrics, 36, pp. 293-310, (1996); Noyons E.C.M., Moed H.F., Van-Raan A.F.J., Integrating research performance analysis and science mapping, Scientometrics, 46, pp. 591-604, (1999); O'Connell A.A., Ingwer B., Patrick G., Modern multidimensional scaling: Theory and applications, Journal of the American Statistical Association, 94, 445, pp. 338-339, (1999); Orduna-Malea E., Delgado-Lopez-Cozar E., Dimensions: Re-discovering the ecosystem of scientific information, El Profesional De La información, 27, 2, pp. 420-431, (2018); Pan X., Yan E., Cui M., Hua W., Examining the usage, citation, and diffusion patterns of bibliometric mapping software: A comparative study of three tools, Journal of Informetrics, 12, 2, pp. 481-493, (2018); Olle P., Rickard D., Jesper W.-S., How to use Bibexcel for various types of bibliometric analysis, Birthday, pp. 9-24, (2009); Pallab P., Science Mapping and Visualization Tools Used in Bibliometric & Scientometric Studies: An over-view”, (2016); Alan P., Statistical bibliography or bibliometrics?, Journal of Documentation, 25, 4, pp. 348-349, (1969); Ruiz-Rosero J., Ramirez-Gonzalez G., Viveros-Delgado J., Software survey: ScientoPy, a scientometric tool for topics trend analysis in scientific publications, Scientometrics, 121, 2, pp. 1165-1188, (2019); Sangam S.L., Mogali S.S., Mapping and visualization softwares tools: A review”, Content Management in Networked Environment, (2012); Science of Science (Sci2) Tool”, (2009); Skute I., Zalewska-Kurek K., Hatak I., De-Weerd-Nederhof P., Mapping the field: A bibliometric analysis of the literature on university–industry collaborations, Journal of Technology Transfer, 44, 3, pp. 916-947, (2019); Henry S., Visualizing science by citation mapping, Journal of the American Society for Information Science, 50, 9, pp. 799-813, (1999); 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Van-Raan A.F.J., Advanced bibliometric methods for the evaluation of universities, Scientometrics, 45, 3, pp. 417-423, (1999); Van-Raan A.F.J., Measuring science. Capita selecta of current main issues, Handbook of Quantitative Science and Technology Research: The Use of Publication and Patent Statistics in Studies of s&t Systems., pp. 19-50, (2004); Van-Raan A.F.J., Sleeping beauties in science, Scientometrics, 59, 3, pp. 467-472, (2004); Veeranjaneyulu K., Altmetrics: New tools to measure research impact in the digitally networked”, National Conference of Agricultural Librarians and User Community, (2017); Waltman L., Van-Eck N.-J., Noyons E.C.M., A unified approach to mapping and clustering of bibliometric networks, Journal of Informetrics, 4, 4, pp. 629-635, (2010)","M.J. Cobo; University of Cadiz, Department of Computer Science and Engineering, Cadiz, Spain; email: manueljesus.cobo@uca.es","","El Profesional de la Informacion","","","","","","13866710","","","","English","Prof. Inf.","Review","Final","All Open Access; Bronze Open Access; Green Open Access","Scopus","2-s2.0-85082037610" -"Ahmed S.A.M.; Zhang W.; Ma H.; Feng Z.","Ahmed, Salah A. M. (57217736355); Zhang, Wenlan (57211554652); Ma, Hongliang (58045534400); Feng, Zhichao (58250313700)","57217736355; 57211554652; 58045534400; 58250313700","Professional development for STEM educators: A bibliometric analysis of the recent progress","2023","Review of Education","11","1","e3392","","","","5","10.1002/rev3.3392","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85159308191&doi=10.1002%2frev3.3392&partnerID=40&md5=d78363e92051c25dc7b6bc1582811345","School of Education, Shaanxi Normal University, Shaanxi, Xi'an, China","Ahmed S.A.M., School of Education, Shaanxi Normal University, Shaanxi, Xi'an, China; Zhang W., School of Education, Shaanxi Normal University, Shaanxi, Xi'an, China; Ma H., School of Education, Shaanxi Normal University, Shaanxi, Xi'an, China; Feng Z., School of Education, Shaanxi Normal University, Shaanxi, Xi'an, China","STEM teacher professional development (STEM-TPD) has become a hot topic of educational research. To evaluate the main characteristics, status and trends of this educational field and to provide new insights for future studies, this review applies a bibliometric analysis of relevant publications. The Web of Science (WoS) core collection database was used as the source of bibliographic data for the period 2011–2021; specifically, 776 articles published in 232 journals were selected for this review. The bibliometric analysis was then carried out using Bibliometrix and VOSviewer to explore trends and patterns in the STEM-TDP literature. It is essential to note that the analysis does not account for the quality of the selected studies. However, it presents the results using various perspectives such as citation, co-citation, spatial and lexical networks based on frequencies, network analysis and descriptive patterns. The findings show that the number of relevant publications has grown significantly in recent years, in particular from 2015 to 2021. The findings, based on citation metrics, highlight the most influential authors, institutions and journals in the area. Authors from different countries have contributed to this research area, but there is a low volume of international collaboration among them. The analysis also reveals the dynamic changes in trends, keywords and themes in this research area. The review concludes with some recommendations for future research, and the suggested implications may also benefit other stakeholders in STEM education. Context and Implications Rationale for the study STEM education has garnered researchers' interest over the past two decades, but there are few reviews of STEM teacher professional development (STEM-TPD) publications. Therefore, this bibliometric review sought to investigate the expansion of STEM-TPD research. It also serves as a roadmap for future TPD research in STEM education. Why do the new findings matter? This comprehensive bibliometric study analysed 776 research publications on STEM-TPD that were published in journals that were indexed by WoS. The findings shed light on recent developments, patterns and trends in STEM-TPD research, as well as international collaboration in STEM-TPD research. Implications for researchers, practitioners and policy makers The overall findings may benefit the researchers, editorial board, and publishers to focus more on some emerging research themes, which can guide the focus of future research. STEM researchers should consider conducting more ambitious, high-quality empirical research that is likely to yield robust results. They can investigate higher-order thinking skills and other issues related to equity, gender inequality, and teacher attrition. The results also inspire researchers and research institutions to boost international collaboration. Similarly, policy makers and higher education institutions should implement more reforms to educational policies and teacher preparation programmes to improve and sustain STEM education. © 2023 British Educational Research Association.","bibliometric analysis; citation analysis; educational research trend; science mapping; scientific collaboration; STEM education; teacher professional development","","","","","","","","Al Salami M.K., Makela C.J., de Miranda M.A., Assessing changes in teachers' attitudes toward interdisciplinary STEM teaching, International Journal of Technology and Design Education, 27, 1, pp. 63-88, (2017); Allen C.D., Penuel W.R., Studying Teachers' sensemaking to investigate Teachers' responses to professional development focused on new standards, Journal of Teacher Education, 66, 2, pp. 136-149, (2015); Alvarado L.E., Aragon R.R., Bretones F.D., Teachers' attitudes towards the introduction of ICT in Ecuadorian public schools, TechTrends, 64, 3, pp. 498-505, (2020); 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Avila-Garzon C., Bacca-Acosta J., Kinshuk Duarte J., Betancourt J., Augmented reality in education: An overview of twenty-five years of research, Contemporary Educational Technology, 13, 3, (2021); Barak M., Asakle S., AugmentedWorld: Facilitating the creation of location-based questions, Computers & Education, 121, pp. 89-99, (2018); Barbosa M.L.D.O., Galembeck E., Mapping research on biochemistry education: A bibliometric analysis, Biochemistry and Molecular Biology Education, 50, 2, pp. 201-215, (2022); Bell R.L., Maeng J.L., Binns I.C., Learning in context: Technology integration in a teacher preparation program informed by situated learning theory, Journal of Research in Science Teaching, 50, 3, pp. 348-379, (2013); Bhattacharyya S.S., Verma S., The intellectual contours of corporate social responsibility literature: Co-citation analysis study, International Journal of Sociology and Social Policy, 40, 11-12, pp. 1551-1583, (2020); Blanchard M.R., LePrevost C.E., Tolin A.D., Gutierrez K.S., Investigating technology-enhanced teacher professional development in rural, high-poverty middle schools, Educational Researcher, 45, 3, pp. 207-220, (2016); Broadus R.N., Toward a definition of “bibliometrics”, Scientometrics, 12, 5, pp. 373-379, (1987); Brophy S., Klein S., Portsmore M., Rogers C., Advancing engineering education in P-12 classrooms, Journal of Engineering Education, 97, 3, pp. 369-387, (2008); Bybee R.W., The case for STEM education: Challenges and opportunities, (2013); Carpenter S.L., Iveland A., Moon S., Hansen A.K., Harlow D.B., Bianchini J.A., Models are a “metaphor in your brain”: How potential and preservice teachers understand the science and engineering practice of modeling, School Science and Mathematics, 119, 5, pp. 275-286, (2019); Cavlazoglu B., Stuessy C., Changes in science teachers' conceptions and connections of STEM concepts and earthquake engineering, The Journal of Educational Research, 110, 3, pp. 239-254, (2017); Cavlazoglu B., Stuessy C., Examining science Teachers' argumentation in a teacher workshop on earthquake engineering, Journal of Science Education and Technology, 27, 4, pp. 348-361, (2018); Cetin M., Demircan H.O., Empowering technology and engineering for STEM education through programming robots: A systematic literature review, Early Child Development and Care, 190, 9, pp. 1323-1335, (2020); Chai C.S., Teacher professional development for science, technology, engineering and mathematics (STEM) education: A review from the perspectives of technological pedagogical content (TPACK), The Asia-Pacific Education Researcher, 28, 1, pp. 5-13, (2019); Chang J., Park J., Developing teacher professionalism for teaching socio-scientific issues: What and how should teachers learn?, Cultural Studies of Science Education, 15, 2, pp. 423-431, (2020); Chen Y.-H., Jang S.-J., Chen P.-J., Using wikis and collaborative learning for science teachers' professional development, Journal of Computer Assisted Learning, 31, 4, pp. 330-344, (2015); Christian K.B., Kelly A.M., Bugallo M.F., NGSS-based teacher professional development to implement engineering practices in STEM instruction, International Journal of STEM Education, 8, 1, (2021); Cividatti L.N., Moralles V.A., Bego A.M., Incidence of design-based research methodology in science education articles: A bibliometric analysis, Brazilian Journal of Research in Science Education, 21, pp. 1-22, (2021); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., Science mapping software tools: Review, analysis, and cooperative study among tools, Journal of the American Society for Information Science and Technology, 62, 7, pp. 1382-1402, (2011); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., SciMAT: A new science mapping analysis software tool, Journal of the American Society for Information Science and Technology, 63, 8, pp. 1609-1630, (2012); Costa H.J.T., Barcala-Furelos R., Abelairas-Gomez C., Arufe-Giraldez V., The influence of a structured physical education plan on preschool children's psychomotor development profiles, Australasian Journal of Early Childhood, 40, 2, pp. 68-77, (2015); Dailey D., Cotabish A., Jackson N., Increasing early opportunities in engineering for advanced learners in elementary classrooms: A review of recent literature, Journal for the Education of the Gifted, 41, 1, pp. 93-105, (2018); Dare E.A., Ring-Whalen E.A., Roehrig G.H., Creating a continuum of STEM models: Exploring how K-12 science teachers conceptualize STEM education, International Journal of Science Education, 41, 12, pp. 1701-1720, (2019); DeCoito I., Estaiteyeh M., Transitioning to online teaching during the COVID-19 pandemic: An exploration of STEM Teachers' views, successes, and challenges, Journal of Science Education and Technology, 31, 3, pp. 340-356, (2022); Dehdarirad T., Villarroya A., Barrios M., Research on women in science and higher education: A bibliometric analysis, Scientometrics, 103, 3, pp. 795-812, (2015); Dickes A.C., Farris A.V., Sengupta P., Sociomathematical norms for integrating coding and modeling with elementary science: A dialogical approach, Journal of Science Education and Technology, 29, 1, pp. 35-52, (2020); Doyle J., Sonnert G., Sadler P., How professional development program features impact the knowledge of science teachers, Professional Development in Education, 46, 2, pp. 195-210, (2020); Dubinsky J.M., Guzey S.S., Schwartz M.S., Roehrig G., MacNabb C., Schmied A., Hinesley V., Hoelscher M., Michlin M., Schmitt L., Ellingson C., Chang Z., Cooper J.L., Contributions of neuroscience knowledge to teachers and their practice, The Neuroscientist, 25, 5, pp. 394-407, (2019); Durdu L., Dag F., Pre-service Teachers' TPACK development and conceptions through a TPACK-based course, Australian Journal of Teacher Education, 42, 11, pp. 150-171, (2017); Durksen T.L., Sheridan L., Tindall-Ford S., Pre-service science and mathematics teachers' reasoning: A think-aloud study, Educational Studies, pp. 1-16, (2021); Ellegaard O., The application of bibliometric analysis: Disciplinary and user aspects, Scientometrics, 116, 1, pp. 181-202, (2018); English L.D., Advancing elementary and middle school STEM education, International Journal of Science and Mathematics Education, 15, 1, pp. 5-24, (2017); Esen M., Bellibas M.S., Gumus S., The evolution of leadership research in higher education for two decades (1995-2014): A bibliometric and content analysis, International Journal of Leadership in Education, 23, 3, pp. 259-273, (2020); Falloon G., Forbes A., Stevenson M., Bower M., Hatzigianni M., STEM in the making? 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Zervas P., Tsourlidaki E., Cao Y., Sotiriou S., Sampson D.G., Faltin N., A study on the use of a metadata schema for characterizing school education STEM lessons plans by STEM teachers, Journal of Computing in Higher Education, 28, 3, pp. 389-405, (2016); Zhang B.H., Ahmed S.A.M., Systems thinking—Ludwig Von Bertalanffy, Peter Senge, and Donella Meadows, Science Education in Theory and Practice, pp. 419-436, (2020); Zhang J., Yu Q., Zheng F., Long C., Lu Z., Duan Z., Comparing keywords plus of WOS and author keywords: A case study of patient adherence research, Journal of the Association for Information Science and Technology, 67, 4, pp. 967-972, (2016); Zupic I., Cater T., Bibliometric methods in management and organization, Organizational Research Methods, 18, 3, pp. 429-472, (2015)","W. Zhang; School of Education, Shaanxi Normal University, Xi'an, No.199 Chang'an South Rd., 710062, China; email: wenlan19@163.com","","John Wiley and Sons Inc","","","","","","20496613","","","","English","Rev. Educ.","Review","Final","","Scopus","2-s2.0-85159308191" -"Xiao Z.; Qin Y.; Xu Z.; Antucheviciene J.; Zavadskas E.K.","Xiao, Zhiwen (57396275400); Qin, Yong (57205945371); Xu, Zeshui (55502698400); Antucheviciene, Jurgita (11139049000); Zavadskas, Edmundas Kazimieras (6602254601)","57396275400; 57205945371; 55502698400; 11139049000; 6602254601","The Journal Buildings: A Bibliometric Analysis (2011–2021)","2022","Buildings","12","1","37","","","","35","10.3390/buildings12010037","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122233844&doi=10.3390%2fbuildings12010037&partnerID=40&md5=3185d8ea3652f81f3aa7ed62e4e1ab5f","Business School, Sichuan University, Chengdu, 610064, China; Department of Construction Management and Real Estate, Vilnius Gediminas Technical University, Sauletekio al. 11, Vilnius, LT-10223, Lithuania; Institute of Sustainable Construction, Vilnius Gediminas Technical University, Sauletekio al. 11, Vilnius, LT-10223, Lithuania","Xiao Z., Business School, Sichuan University, Chengdu, 610064, China; Qin Y., Business School, Sichuan University, Chengdu, 610064, China; Xu Z., Business School, Sichuan University, Chengdu, 610064, China; Antucheviciene J., Department of Construction Management and Real Estate, Vilnius Gediminas Technical University, Sauletekio al. 11, Vilnius, LT-10223, Lithuania; Zavadskas E.K., Institute of Sustainable Construction, Vilnius Gediminas Technical University, Sauletekio al. 11, Vilnius, LT-10223, Lithuania","The journal Buildings was launched in 2011 and is dedicated to promoting advancements in building science, building engineering and architecture. Motivated by its 10th anniversary in 2021, this study aims to develop a bibliometric analysis of the publications of the journal between April 2011 and October 2021. This work analyzes bibliometric performance indicators, such as publication and citation structures, the most cited articles and the leading authors, institutions and countries/regions. Science mappings based on indicators such as the most commonly used keywords, citation and co-citation, and collaboration are also developed for further analysis. In doing so, the work uses the Scopus database to collect data and Bibliometrix to conduct the research. The results show the strong growth of Buildings over time and that researchers from all over the world are attracted by the journal. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.","Bibliometrics; Bibliometrix; Science mapping; Scopus","","","","","","National Natural Science Foundation of China, NSFC, (71771155, 72071135); National Natural Science Foundation of China, NSFC","Funding: The work was supported by the National Natural Science Foundation of China (Nos. 72071135 and 71771155).","Anumba C.J., Buildings: An open access journal for the built environment, Buildings, 1, pp. 1-3, (2011); Kessler M.M., Bibliographic coupling between scientific papers, Am. Doc, 14, pp. 10-25, (1963); Small H., Co-citation in the scientific literature: A new measure of the relationship between two documents, J. Am. Soc. Inf. Sci, 24, pp. 265-269, (1973); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr, 11, pp. 959-975, (2017); Yu D.J., Xu Z.S., Antucheviciene J., Bibliometric analysis of the Journal of Civil Engineering and Management between 2008 and 2018, J. Civ. Eng. Manag, 25, pp. 402-410, (2019); Tang M., Liao H., Yepes V., Laurinavicius A., Tupenaite L., Quantifying and mapping the evolution of a leader journal in the field of civil engineering, J. Civ. Eng. Manag, 27, pp. 100-116, (2021); Novas N., Alcayde A., Robalo I., Manzano-Agugliaro F., Montoya F.G., Energies and Its Worldwide Research, Energies, 13, (2020); Zhou W., Xu Z.S., Zavadskas E.K., Laurinavicius A., The knowledge domain of the Baltic Journal of Road and Bridge Engineering between 2006 and 2019, Baltic J. Road Bridge Eng, 15, pp. 1-30, (2020); Wang X.X., Xu Z.S., Ge Z.J., Zavadskas E.K., Skackauskas P., An overview of a leader journal in the field of transport: A bibliometric analysis of “Computer-aided civil and infrastructure engineering” from 2000 to2019, Transport, 35, pp. 557-575, (2021); Cobo M.J., Martinez M.A., Gutierrez-Salcedo M., Fujita H., Herrera-Viedma E., 25 years at Knowledge-Based Systems: A bibliometric analysis, Knowl.-Based Syst, 80, pp. 3-13, (2015); Wang X.X., Chang Y., Xu Z.S., Wang Z.D., Kadirkamanathan V., 50 years of international journal of systems science: A review of the past and trends for the future, Int. J. Syst. Sci, 52, pp. 1515-1538, (2021); Yu D., Xu Z.S., Pedrycz W., Wang W., Information sciences 1968–2016: A retrospective analysis with text mining and bibliometric, Inf. Sci, (2017); Rousseau R., Forgotten founder of bibliometrics, Nature, 510, (2014); Broadus R.N., Toward a definition of “bibliometrics”, Scientometrics, 12, pp. 373-379, (1987); Merigo J.M., Cobo M.J., Laengle S., Rivas D., Herrera-Viedma E., Twenty years of Soft Computing: A bibliometric overview, Soft Comput, 23, pp. 1477-1497, (2019); Cancino C., Merigo J.M., Coronado F., Dessouky Y., Dessouky M., Forty years of Computers & Industrial Engineering: A bibliometric analysis, Comput. Ind. Eng, 113, pp. 614-629, (2017); Akadiri P.O., Chinyio E.A., Olomolaiye P.O., Design of a sustainable building: A conceptual framework for implementing sustainability in the building sector, Buildings, 2, pp. 126-152, (2012); Al-Kodmany K., The Vertical Farm: A review of developments and implications for the vertical city, Buildings, 8, (2018); Tahmasebinia F., Niemela M., Ebrahimzadeh Sepasgozar S.M., Lai T.Y., Su W., Reddy K.R., Shirowzhan S., Sepasgozar S., Marroquin F.A., Three-Dimensional printing using recycled high-density polyethylene: Technological challenges and future directions for construction, Buildings, 8, (2018); Tahmasebinia F., Fogerty D., Wu L.O., Li Z., Sepasgozar S.M.E., Zhang K., Sepasgozar S., Marroquin F.A., Numerical analysis of the creep and shrinkage experienced in the Sydney Opera House and the rise of digital twin as future monitoring technology, Buildings, 9, (2019); Sepasgozar S.M.E., Shi A., Yang L., Shirowzhan S., Edwards D.J., Additive manufacturing applications for Industry 4.0: A systematic critical review, Buildings, 10, (2020); Al-Kodmany K., Green retrofitting skyscrapers: A review, Buildings, 4, pp. 683-710, (2014); Al-Kodmany K., The sustainability of tall building developments: A conceptual framework, Buildings, 8, (2018); Al-Kodmany K., New Suburbanism: Sustainable spatial patterns of tall buildings, Buildings, 8, (2018); Al-Kodmany K., Sustainability and the 21st century vertical city: A review of design approaches of tall buildings, Buildings, 8, (2018); Wang L., Wei Y.M., Brown M.A., Global transition to low-carbon electricity: A bibliometric analysis, Appl. Energy, 205, pp. 57-68, (2017); Mumu J.R., Tahmid T., Azad M.d.A.K., Job satisfaction and intention to quit: A bibliometric review of work-family conflict and research agenda, Appl. Nurs. Res, 59, (2021); Aria M., Misuraca M., Spano M., Mapping the evolution of social research and data science on 30 years of Social Indicators Research, Soc. Indic. Res, 149, pp. 803-831, (2020); Srivastava M., Mapping the influence of influencer marketing: A bibliometric analysis, Mark. Intell. Plan, 39, pp. 979-1003, (2021); Vinokurov M., Gronman K., Kosonen A., Luoranen M., Soukka R., Updating the path to a carbon-neutral built environment— What should a single builder do, Buildings, 8, (2018); Vinokurov M., Gronman K., Hammo S., Soukka R., Luoranen M., Integrating energy efficiency into the municipal procurement process of buildings—Whose responsibility?, Buildings, 9, (2019); Fargnoli M., Lombardi M., Preliminary Human Safety Assessment (PHSA) for the improvement of the behavioral aspects of safety climate in the construction industry, Buildings, 9, (2019); Fargnoli M., Lombardi M., Building Information Modelling (BIM) to enhance occupational safety in construction activities: Research trends emerging from one decade of studies, Buildings, 10, (2020); Kouris E.-G.S., Kouris L.-A.S., Konstantinidis A.A., Kourkoulis S.K., Karayannis C.G., Aifantis E.C., Stochastic dynamic analysis of cultural heritage towers up to collapse, Buildings, 11, (2021); Shehu R., Implementation of pushover analysis for seismic assessment of masonry towers: Issues and practical recommendations, Buildings, 11, (2021); Asikoglu A., Vasconcelos G., Lourenco P.B., Overview on the nonlinear static procedures and performance-based approach on modern unreinforced masonry buildings with structural irregularity, Buildings, 11, (2021); Guleria D., Kaur G., Bibliometric analysis of ecopreneurship using VOSviewer and RStudio Bibliometrix, 1989–2019, Libr. Hi Tech, 39, pp. 1001-1024, (2021); Noyons E.C.M., Moed H.F., Luwel M., Combining mapping and citation analysis for evaluative bibliometric purposes: A bibliometric study, J. Am. Soc. Inf. Sci, 50, pp. 115-131, (1999)","Z. Xu; Business School, Sichuan University, Chengdu, 610064, China; email: xuzeshui@263.net","","MDPI","","","","","","20755309","","","","English","Buildings","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85122233844" -"Omotehinwa T.O.","Omotehinwa, Temidayo Oluwatosin (57216311748)","57216311748","Examining the developments in scheduling algorithms research: A bibliometric approach","2022","Heliyon","8","5","e09510","","","","36","10.1016/j.heliyon.2022.e09510","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85131086909&doi=10.1016%2fj.heliyon.2022.e09510&partnerID=40&md5=d16661e70c0b9546fad1ca18ceb7fceb","Department of Mathematics and Computer Science, Federal University of Health Sciences, Otukpo, Nigeria","Omotehinwa T.O., Department of Mathematics and Computer Science, Federal University of Health Sciences, Otukpo, Nigeria","This study examined the developments in the field of Scheduling algorithms in the last 30 years (1992–2021) to help researchers gain new insight and uncover the emerging areas of growth for further research in this field. This study, therefore, carried out a bibliometric analysis of 12,644 peer-reviewed documents extracted from the Scopus database using the Bibliometrix R package for bibliometric analysis via the Biblioshiny web interface. The results of this study established the development status of the field of Scheduling Algorithms, the growth rate, and emerging thematic areas for further research, institutions, and country collaborations. It also identified the most impactful and leading authors, keywords, sources, and publications in this field. These findings can help both budding and established researchers to find new research focus and collaboration opportunities and make informed decisions as they research the field of scheduling algorithms and their applications. © 2022 The Author(s)","Bibliometric analysis; Bibliometrix; Biblioshiny; Scheduling algorithms; Science mapping","","","","","","Centre for Multidisciplinary Research and Innovation","I appreciate the efforts of Agbo, Friday Joseph and Dr. Emmanuel Mogaji at the Centre for Multidisciplinary Research and Innovation (CEMRI) for their assistance during the data collection period and proofreading. Also, the immense contributions of the section editor and reviewers to improve the quality of the manuscript are highly appreciated. I am very grateful to the publisher for granting a full waiver of the article processing charge.","Agrawal P., Gupta A.K., Mathur P., CPU scheduling in operating system: a review, Lect. Notes Netw. 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Omotehinwa; Department of Mathematics and Computer Science, Federal University of Health Sciences, Otukpo, Nigeria; email: oluomotehinwa@gmail.com","","Elsevier Ltd","","","","","","24058440","","","","English","Heliyon","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85131086909" -"Sharma P.; Singh R.; Tamang M.; Singh A.K.; Singh A.K.","Sharma, Primula (57219943666); Singh, Ranjit (57218869877); Tamang, Manila (57219939029); Singh, Amit Kumar (59639966800); Singh, Akhilesh Kumar (59463066700)","57219943666; 57218869877; 57219939029; 59639966800; 59463066700","Journal of teaching in travel &tourism: a bibliometric analysis","2021","Journal of Teaching in Travel and Tourism","21","2","","155","176","21","44","10.1080/15313220.2020.1845283","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096158948&doi=10.1080%2f15313220.2020.1845283&partnerID=40&md5=9bdf46645c23558360dbd31b693ccc0f","Department of Tourism, Sikkim University, Gangtok, India; Department of Tourism Studies, Pondicherry University, Pondicherry, India","Sharma P., Department of Tourism, Sikkim University, Gangtok, India; Singh R., Department of Tourism Studies, Pondicherry University, Pondicherry, India; Tamang M., Department of Tourism, Sikkim University, Gangtok, India; Singh A.K., Department of Tourism, Sikkim University, Gangtok, India; Singh A.K., Department of Tourism, Sikkim University, Gangtok, India","Journal of Teaching in Travel & Tourism (JTTT) is a widely acknowledged journal for its contribution to scientific knowledge development in travel and tourism education. Understanding the developmental trajectory of JTTT in the context of tourism and hospitality education is highly relevant for academic research and practice. This study sets out to present the scientific development, productivity, influence, and research trends of JTTT from 2001 to 2019 through bibliometric analysis. A sample of 407 documents extracted from the Scopus database were analysed with techniques such as descriptive, conceptual structure, intellectual structure and social structure analyses. The study uses the scientometric tool “bibliometrix” written in R programming language for science mapping. Findings from the analysis identified that JTTT is a leading tourism journal in the field of travel and tourism education focusing on a wide range of topics, with publications from various authors, institutions, and countries. © 2020 Informa UK Limited, trading as Taylor & Francis Group.","bibliometric analysis; bibliometrix; Journal of Teaching in Travel & Tourism; travel and tourism education","","","","","","","","Ali F., Park E., Kwon J., Chae B., 30 years of contemporary hospitality management: Uncovering the bibliometrics and topical trends, International Journal of Contemporary Hospitality Management, 31, 7, pp. 2641-2665, (2019); Aria M., Cuccurullo C., bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11, 4, pp. 959-975, (2017); Aria M., Cuccurullo C., Package ‘bibliometrix, (2020); Aria M., Cuccurullo C., Science mapping analysis with bibliometrix R-package: An example, (2020); Bandura A., Social foundations of thought and action: A social cognitive theory, (1986); Barber E., Case study: Integrating TEFI (Tourism Education Futures Initiative) core values into the undergraduate curriculum, Journal of Teaching in Travel and Tourism, 11, 1, pp. 38-75, (2011); Barron P., Issues surrounding asian students hospitality management in australia: A literature review regarding the paradox of the asian learner, Journal of Teaching in Travel and Tourism, 2, 3-4, pp. 23-45, (2002); Barron P., Learning issues and learning problems of confucian heritage culture students studying hospitality and tourism management in Australia, Journal of Teaching in Travel and Tourism, 6, 4, pp. 1-17, (2006); Behnke C., Ghiselli R., A comparison of educational delivery techniques in a foodservice training environment, Journal of Teaching in Travel and Tourism, 4, 1, pp. 41-56, (2004); Benckendorff P., Zehrer A., A network analysis of tourism research, Annals of Tourism Research, 43, pp. 121-149, (2013); Bloom B.S., Taxonomy of educational objectives: The classification of educational goals, (1956); 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Tamang; Sikkim University, Gangtok, 737102, India; email: manilatamang05@gmail.com","","Routledge","","","","","","15313220","","","","English","J. Teach Travel Tour.","Article","Final","","Scopus","2-s2.0-85096158948" -"Marcal J.; Bishop T.; Hofman J.; Shen J.","Marcal, Juliana (57226021113); Bishop, Toby (57226031339); Hofman, Jan (7103362371); Shen, Junjie (56502630500)","57226021113; 57226031339; 7103362371; 56502630500","From pollutant removal to resource recovery: A bibliometric analysis of municipal wastewater research in Europe","2021","Chemosphere","284","","131267","","","","44","10.1016/j.chemosphere.2021.131267","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110094613&doi=10.1016%2fj.chemosphere.2021.131267&partnerID=40&md5=d9691fe1c65457a948263431faa6684f","Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK, United Kingdom; Water Innovation and Research Centre (WIRC), University of Bath, Bath, BA2 7AY, UK, United Kingdom; Centre for Advanced Separations Engineering (CASE), University of Bath, Bath, BA2 7AY, UK, United Kingdom; KWR Water Research Institute, PO Box 1072, Nieuwegein, 3430 BB, Netherlands","Marcal J., Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK, United Kingdom, Water Innovation and Research Centre (WIRC), University of Bath, Bath, BA2 7AY, UK, United Kingdom; Bishop T., Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK, United Kingdom; Hofman J., Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK, United Kingdom, Water Innovation and Research Centre (WIRC), University of Bath, Bath, BA2 7AY, UK, United Kingdom, KWR Water Research Institute, PO Box 1072, Nieuwegein, 3430 BB, Netherlands; Shen J., Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK, United Kingdom, Water Innovation and Research Centre (WIRC), University of Bath, Bath, BA2 7AY, UK, United Kingdom, Centre for Advanced Separations Engineering (CASE), University of Bath, Bath, BA2 7AY, UK, United Kingdom","Municipal wastewaters are abundant low-strength streams that require adequate treatment and disposal to ensure public and environmental health. This study aims to provide a comprehensive summary of municipal wastewater research in Europe in the 2010s in the form of bibliometric analysis. The work was based on the Science Citation Index Expanded (Web of Science) and carried out using the R-package bibliometrix for bibliometric data analysis and the software VOSviewer for science mapping. Analysing a dataset of 5645 publications, we identified the most influential journals, countries, authors, institutions, and publications, and mapped the co-authorship and keyword co-occurrence networks. Spain had produced the most publications while Switzerland had the highest average citations per publication. China was the most collaborative country from outside of Europe. Analysis of the most cited articles revealed the popularity of micropollutant removal in European municipal wastewater research. The keyword analysis visualized a paradigm shift from pollutant removal towards resource recovery and circular economy. We found that current challenges of resource recovery from municipal wastewater come from both technical and non-technical (e.g., environmental, economic, and social) aspects. We also discussed future research opportunities that can tackle these challenges. © 2021 Elsevier Ltd","Bibliometric analysis; Circular economy; Europe; Micropollutant; Municipal wastewater; Resource recovery","Bibliometrics; China; Environmental Pollutants; Europe; Waste Water; Europe; Publishing; Recovery; Wastewater disposal; Wastewater treatment; Bibliometrics analysis; Circular economy; Environmental health; Europe; Micropollutants; Municipal wastewaters; Pollutants removal; Resource recovery; Science citation index; Treatment and disposal; data set; environmental economics; paradigm shift; pollutant removal; research program; resource management; wastewater; wastewater treatment; article; China; data analysis; economic aspect; human; municipal wastewater; recycling; SciSearch; software; Spain; Switzerland; Web of Science; writing; bibliometrics; Europe; pollutant; wastewater; Pollution","","Environmental Pollutants, ; Waste Water, ","","","; European Commission, EC; Water Informatics Science and Engineering; European Commission denounced Spain; WISE; European Court of Justice; Technische Universiteit Delft, TU Delft; Royal Academy of Engineering, RAENG, (RF_201718_17145); Engineering and Physical Sciences Research Council, EPSRC, (EP/L016214/1)","Funding text 1: The high research output from Spain could be attributed to several laws and grants from the Spanish government imposed to aid Spain in meeting targets set out by the EU. Specifically, a budget of around \u20AC20 million was allocated in 2007 to achieve complete compliance with the WFD and other EU laws. However, in 2014 the European Commission denounced Spain to the European Court of Justice for not ensuring correct treatment of urban wastewaters in several municipalities, which eventually led to a fine of \u20AC12 million (Jodar-Abellan et al., 2019). As a result of this, Spain enacted the Spanish Plan of Measures for Growth, Competitiveness and Efficiency. The plan had an initial goal of achieving water purity in surface waters in line with the WFD by 2020, and issued a grant of around \u20AC1 billion to be invested in over 400 WWTPs (Jodar-Abellan et al., 2019). These arguments provide potential evidence to explain why Spain has been the largest contributor to wastewater research over the past decade.Juliana Marcal is supported by a PhD studentship from the Water Informatics Science and Engineering (WISE) Centre for Doctoral Training (CDT), funded by the UK Engineering and Physical Sciences Research Council (EPSRC), Grant No. EP/L016214/1. The authors acknowledge Prof. Mark van Loosdrecht (Delft University of Technology) for providing valuable comments. This project was supported by the Royal Academy of Engineering under the Research Fellowship scheme (RF_201718_17145).; Funding text 2: Juliana Marcal is supported by a PhD studentship from the Water Informatics Science and Engineering ( WISE ) Centre for Doctoral Training ( CDT ), funded by the UK Engineering and Physical Sciences Research Council (EPSRC), Grant No. EP/L016214/1. The authors acknowledge Prof. Mark van Loosdrecht (Delft University of Technology) for providing valuable comments. This project was supported by the Royal Academy of Engineering under the Research Fellowship scheme ( RF_201718_17145 ). ","Amorim de Carvalho C.D., Ferreira dos Santos A., Tavares Ferreira T.J., Sousa Aguiar Lira V.N., Mendes Barros A.R., Bezerra dos Santos A., Resource recovery in aerobic granular sludge systems: is it feasible or still a long way to go?, Chemosphere, 274, (2021); Aria M., Cuccurullo C., bibliometrix: an R-tool for comprehensive science mapping analysis, J. Informetr., 11, pp. 959-975, (2017); Arola K., Van der Bruggen B., Manttari M., Kallioinen M., Treatment options for nanofiltration and reverse osmosis concentrates from municipal wastewater treatment: a review, Crit. Rev. Environ. Sci. 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Shen; Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, United Kingdom; email: J.Shen@bath.ac.uk","","Elsevier Ltd","","","","","","00456535","","CMSHA","34217935","English","Chemosphere","Article","Final","All Open Access; Green Open Access","Scopus","2-s2.0-85110094613" -"Martynov I.; Klima-Frysch J.; Schoenberger J.","Martynov, Illya (57203535326); Klima-Frysch, Jessica (57203531922); Schoenberger, Joachim (57203536275)","57203535326; 57203531922; 57203536275","A scientometric analysis of neuroblastoma research","2020","BMC Cancer","20","1","486","","","","45","10.1186/s12885-020-06974-3","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085642559&doi=10.1186%2fs12885-020-06974-3&partnerID=40&md5=9c40f3e48652f70fc52fe746403dc207","Department of Pediatric Surgery, University Hospital of Freiburg, Freiburg, Germany; Department of Pediatric Surgery, University of Leipzig, Leipzig, Germany","Martynov I., Department of Pediatric Surgery, University Hospital of Freiburg, Freiburg, Germany, Department of Pediatric Surgery, University of Leipzig, Leipzig, Germany; Klima-Frysch J., Department of Pediatric Surgery, University Hospital of Freiburg, Freiburg, Germany; Schoenberger J., Department of Pediatric Surgery, University Hospital of Freiburg, Freiburg, Germany","Background: Thousands of research articles on neuroblastoma have been published over the past few decades; however, the heterogeneity and variable quality of scholarly data may challenge scientists or clinicians to survey all of the available information. Hence, holistic measurement and analyzation of neuroblastoma-related literature with the help of sophisticated mathematical tools could provide deep insights into global research performance and the collaborative architectonical structure within the neuroblastoma scientific community. In this scientometric study, we aim to determine the extent of the scientific output related to neuroblastoma research between 1980 and 2018. Methods: We applied novel scientometric tools, including Bibliometrix R package, biblioshiny, VOSviewer, and CiteSpace IV for comprehensive science mapping analysis of extensive bibliographic metadata, which was retrieved from the Web of ScienceTM Core Collection database. Results: We demonstrate the enormous proliferation of neuroblastoma research during last the 38 years, including 12,435 documents published in 1828 academic journals by 36,908 authors from 86 different countries. These documents received a total of 316,017 citations with an average citation per document of 28.35 ± 7.7. We determine the proportion of highly cited and never cited papers, ""occasional"" and prolific authors and journals. Further, we show 12 (13.9%) of 86 countries were responsible for 80.4% of neuroblastoma-related research output. Conclusions: These findings are crucial for researchers, clinicians, journal editors, and others working in neuroblastoma research to understand the strengths and potential gaps in the current literature and to plan future investments in data collection and science policy. This first scientometric study of global neuroblastoma research performance provides valuable insight into the scientific landscape, co-authorship network architecture, international collaboration, and interaction within the neuroblastoma community. © 2020 The Author(s).","Children; Network analysis; Neuroblastoma; Research performance; Scientometrics","Bibliometrics; Biomedical Research; Child; Databases, Factual; Humans; Metadata; Neuroblastoma; Article; bibliometrics; cancer research; citation analysis; clinician; editor; human; information processing; international cooperation; medical literature; neuroblastoma; publication; scientist; scientometric analysis; Web of Science; bibliometrics; child; factual database; medical research; metadata","","","","","","","Matthay K.K., Maris J.M., Schleiermacher G., Nakagawara A., Mackall C.L., Diller L., Et al., Neuroblastoma, Nat Rev Dis Primers, 2, 1, (2016); Esiashvili N., Anderson C., Katzenstein H.M., Neuroblastoma, Curr Probl Cancer, 33, 6, pp. 333-360, (2009); Maris J.M., Recent advances in neuroblastoma, N Engl J Med, 362, 23, pp. 2202-2211, (2010); Smith M.A., Seibel N.L., Altekruse S.F., Ries L.A., Melbert D.L., O'Leary M., Et al., Outcomes for children and adolescents with cancer: Challenges for the twenty-first century, J Clin Oncol, 28, 15, pp. 2625-2634, (2010); Spix C., Pastore G., Sankila R., Stiller C.A., Steliarova-Foucher E., Neuroblastoma incidence and survival in European children (1978-1997): Report from the Automated Childhood Cancer Information System project, Eur J Cancer (Oxford, England: 1990), 42, 13, pp. 2081-2091, (2006); Decarolis B., Simon T., Krug B., Leuschner I., Vokuhl C., Kaatsch P., Et al., Treatment and outcome of Ganglioneuroma and Ganglioneuroblastoma intermixed, BMC Cancer, 16, (2016); Brodeur G.M., Neuroblastoma: Biological insights into a clinical enigma, Nat Rev Cancer, 3, 3, pp. 203-216, (2003); Johnsen J.I., Dyberg C., Fransson S., Wickstrom M., Molecular mechanisms and therapeutic targets in neuroblastoma, Pharmacol Res, 131, pp. 164-176, (2018); Lee J.W., Son M.H., Cho H.W., Ma Y.E., Yoo K.H., Sung K.W., Et al., Clinical significance of MYCN amplification in patients with high-risk neuroblastoma, Pediatr Blood Cancer, 65, 10, (2018); Valentijn L.J., Koster J., Haneveld F., Aissa R.A., Van Sluis P., Broekmans M.E., Et al., Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification, Proc Natl Acad Sci U S A, 109, 47, pp. 19190-19195, (2012); Trigg R., Turner S., ALK in Neuroblastoma: Biological and Therapeutic Implications, Cancers, 10, 4, (2018); Bresler S.C., Weiser D.A., Huwe P.J., Park J.H., Krytska K., Ryles H., Et al., ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma, Cancer Cell, 26, 5, pp. 682-694, (2014); Van Arendonk K., Chung D., Neuroblastoma: Tumor Biology and Its Implications for Staging and Treatment, Children, 6, 1, (2019); Whittle S.B., Smith V., Doherty E., Zhao S., McCarty S., Zage P.E., Overview and recent advances in the treatment of neuroblastoma, Expert Rev Anticancer Ther, 17, 4, pp. 369-386, (2017); Modak S., Cheung N.K., Neuroblastoma: Therapeutic strategies for a clinical enigma, Cancer Treat Rev, 36, 4, pp. 307-317, (2010); Park J.R., Bagatell R., London W.B., Maris J.M., Cohn S.L., Mattay K.K., Et al., Children's oncology Group's 2013 blueprint for research: Neuroblastoma, Pediatr Blood Cancer, 60, 6, pp. 985-993, (2013); Pinto N.R., Applebaum M.A., Volchenboum S.L., Matthay K.K., London W.B., Ambros P.F., Et al., Advances in risk classification and treatment strategies for neuroblastoma, J Clin Oncol, 33, 27, pp. 3008-3017, (2015); Oeffinger K.C., Mertens A.C., Sklar C.A., Kawashima T., Hudson M.M., Meadows A.T., Et al., Chronic health conditions in adult survivors of childhood cancer, N Engl J Med, 355, 15, pp. 1572-1582, (2006); Laverdiere C., Liu Q., Yasui Y., Nathan P.C., Gurney J.G., Stovall M., Et al., Long-term outcomes in survivors of neuroblastoma: A report from the childhood Cancer survivor study, J Natl Cancer Inst, 101, 16, pp. 1131-1140, (2009); Nguyen R., Dyer MA., Chapter 3-neuroblastoma: Molecular mechanisms and therapeutic interventions. Columbia, SC, United States, Neuroblastoma, pp. 43-61, (2019); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J Informetrics, 11, 4, pp. 959-975, (2017); Hirsch J.E., An index to quantify an individual's scientific research output, Proc Natl Acad Sci U S A, 102, 46, pp. 16569-16572, (2005); Greenacre M.J., Interpreting multiple correspondence analysis, Appl Stochastic ModelsData Anal, 7, 2, pp. 195-210, (1991); Van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, 2, pp. 523-538, (2010); Begum M., Lewison G., Lawler M., Sullivan R., Mapping the European cancer research landscape: An evidence base for national and Pan-European research and funding, Eur J Cancer (Oxford, England: 1990), 100, pp. 75-84, (2018); Syrimi E., Lewison G., Sullivan R., Kearns P., Analysis of global pediatric Cancer research and publications, JCO Global Oncol, 6, pp. 9-18, (2020); Brodeur G.M., Pritchard J., Berthold F., Carlsen N.L., Castel V., Castelberry R.P., Et al., Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment, J Clin Oncol, 11, 8, pp. 1466-1477, (1993); Look A.T., Hayes F.A., Shuster J.J., Douglass E.C., Castleberry R.P., Bowman L.C., Et al., Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: A pediatric oncology group study, J Clin Oncol, 9, 4, pp. 581-591, (1991); Layfield L.J., Thompson J.K., Dodge R.K., Kerns B.J., Prognostic indicators for neuroblastoma: Stage, grade, DNA ploidy, MIB-1-proliferation index, p53, HER-2/neu and EGFr - A survival study, J Surg Oncol, 59, 1, pp. 21-27, (1995); Cabral B.P., Da Graca D.F.M., Mota F.B., The recent landscape of cancer research worldwide: A bibliometric and network analysis, Oncotarget, 9, 55, pp. 30474-30484, (2018); Finch A., 10-citation, Bibliometrics and Quality: Assessing Impact and Usage, pp. 243-267, (2012); Dwivedi S., Garg K.C., Prasad N.H., Scientometric profile of global male breast cancer research, Curr Sci, 112, 9, (2017); Glynn R.W., Scutaru C., Kerin M.J., Sweeney K.J., Breast cancer research output, 1945-2008: A bibliometric and density-equalizing analysis, Breast Cancer Res, 12, 6, (2010); Flotte T.R., The science policy implications of a trump presidency, Hum Gene Ther, 28, 1, pp. 1-2, (2017); Gostin L.O., Government and science: The unitary executive versus freedom of scientific inquiry, Hast Cent Rep, 39, 2, pp. 11-12, (2009); Groneberg-Kloft B., Scutaru C., Kreiter C., Kolzow S., Fischer A., Quarcoo D., Institutional operating figures in basic and applied sciences: Scientometric analysis of quantitative output benchmarking, Health Res Policy Syst, 6, (2008); Greene M., The demise of the lone author, Nature, 450, 7173, (2007); Rosson N.J., Hassoun H.T., Global collaborative healthcare: Assessing the resource requirements at a leading Academic Medical Center, Glob Health, 13, 1, (2017); Butrous G., International cooperation to promote advances in medicine, Ann Thorac Med, 3, 3, pp. 79-81, (2008); Cheung N.K., Dyer M.A., Neuroblastoma: Developmental biology, cancer genomics and immunotherapy, Nat Rev Cancer, 13, 6, pp. 397-411, (2013); Yu A.L., Gilman A.L., Ozkaynak M.F., London W.B., Kreissman S.G., Chen H.X., Et al., Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma, N Engl J Med, 363, 14, pp. 1324-1334, (2010); Merton R.K., The Matthew Effect in Science: The reward and communication systems of science are considered, Science, 159, 3810, pp. 56-63, (1968)","I. Martynov; Department of Pediatric Surgery, University Hospital of Freiburg, Freiburg, Germany; email: illya.martynov@medizin.uni-leipzig.de","","BioMed Central Ltd.","","","","","","14712407","","BCMAC","32471384","English","BMC Cancer","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85085642559" -"Michailidis P.D.","Michailidis, Panagiotis D. (6603144382)","6603144382","A Scientometric Study of the Stylometric Research Field","2022","Informatics","9","3","60","","","","7","10.3390/informatics9030060","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85138709983&doi=10.3390%2finformatics9030060&partnerID=40&md5=e3d7517e639cec2eaed253c2ec111eb2","Department of Balkan, Slavic and Oriental Studies, University of Macedonia, Thessaloniki, 54636, Greece","Michailidis P.D., Department of Balkan, Slavic and Oriental Studies, University of Macedonia, Thessaloniki, 54636, Greece","Stylometry has gained great popularity in digital humanities and social sciences. Many works on stylometry have recently been reported. However, there is a research gap regarding review studies in this field from a bibliometric and evolutionary perspective. Therefore, in this paper, a bibliometric analysis of publications from the Scopus database in the stylometric research field was proposed. Then, research articles published between 1968 and 2021 were collected and analyzed using the Bibliometrix R package for bibliometric analysis via the Biblioshiny web interface. Empirical results were also presented in terms of the performance analysis and the science mapping analysis. From these results, it is concluded that there has been a strong growth in stylometry research in recent years, while the USA, Poland, and the UK are the most productive countries, and this is due to many strong research partnerships. It was also concluded that the research topics of most articles, based on author keywords, focused on two broad thematic categories: (1) the main tasks in stylometry and (2) methodological approaches (statistics and machine learning methods). © 2022 by the author.","bibliometric analysis; biblioshiny; Scopus; stylometry","","","","","","","","Neal T., Sundararajan K., Fatima A., Yan Y., Xiang Y., Woodard D., Surveying stylometry techniques and applications, ACM Comput. Surv, 50, pp. 1-36, (2017); Donthu N., Kumar S., Mukherjee D., Pandey N., Lim W.M., How to conduct a bibliometric analysis: An overview and guidelines, J. Bus. Res, 133, pp. 285-296, (2021); Zupic I., Cater T., Bibliometric methods in management and organization, Organ. Res. Methods, 18, pp. 429-472, (2015); Moral-Munoz J.A., Herrera-Viedma E., Santisteban-Espejo A., Cobo M.J., Software tools for conducting bibliometric analysis in science: An up-to-date review, Prof. Inf, 29, (2020); Aria M., Cuccurullo C., Bibliometrix: An R-tool for comprehensive science mapping analysis, J. Informetr, 11, pp. 959-975, (2017); Argamon S., Koppel M., Fine J., Shimoni A.R., Gender, genre, and writing style in formal written texts, Text Talk, 23, pp. 321-346, (2003); Feng S., Banerjee R., Choi Y., Syntactic stylometry for deception detection, Proceedings of the 50th Annual Meeting of the Association for Computational Linguistics, pp. 171-175; Holmes D.I., The evolution of stylometry in humanities scholarship, Lit. Linguist. Comput, 13, pp. 111-117, (1998); Abbasi A., Chen H., Writeprints: A stylometric approach to identity-level identification and similarity detection in cyberspace, ACM Trans. Inf. Syst, 26, pp. 1-29, (2008); Stamatatos E., Fakotakis N., Kokkinakis G., Automatic text categorization in terms of genre and author, Comput. Linguist, 26, pp. 471-495, (2000); Holmes D.I., Authorship attribution, Comput. Humanit, 28, pp. 87-106, (1994); Narayanan A., Paskov H., Zhenqiang Gong N., Bethencourt J., Stefanov E., Chul Richard Shin E., Song D., On the feasibility of Internet-scale author identification, Proceedings of the IEEE Symposium on Security and Privacy, pp. 300-314; Peersman C., Daelemans W., Vaerenbergh L., Predicting age and gender in online social networks, Proceedings of the 3rd International Workshop on Search and Mining User-Generated Contents, pp. 37-44; Cheng N., Chandramouli R., Subbalakshmi K.P., Author gender identification from text, Digit. Investig, 8, pp. 78-88, (2011); Alzahrani S.M., Salim N., Abraham A., Understanding plagiarism linguistic patterns, textual features, and detection methods, IEEE Trans. Syst. Man Cybern, 42, pp. 133-149, (2012); Afroz S., Brennan M., Greenstadt R., Detecting hoaxes, frauds, and deception in writing style online, Proceedings of the IEEE Symposium on Security and Privacy, pp. 461-475; Holmes D.I., Forsyth R.S., The federalist revisited: New directions in authorship attribution, Lit. Linguist. Comput, 10, pp. 111-127, (1995); Potthast M., Kiesel J., Reinartz K., Bevendorff J., Stein B., A stylometric inquiry into hyperpartisan and fake news, Proceedings of the 56th Annual Meeting of the Association for Computational Linguistics, pp. 231-240; Eder E., Rybicki J., Kestemont M., Stylometry with R: A package for computational text analysis, R J, 8, pp. 107-121, (2016); Caliskan-Islam A., Harang R., Liu A., Narayanan A., Voss C., Yamaguchi F., Greenstadt R., De-anonymizing programmers via code stylometry, Proceedings of the 24th USENIX Security Symposium, pp. 255-270; Lyckx K., Daelemans W., Authorship attribution and verification with many authors and limited data, Proceedings of the Coling 2008—22nd International Conference on Computational Linguistics, pp. 513-520; Rocha A., Scheirer W.J., Forstall C.W., Cavalcante T., Theophilo A., Shen B., Carvalho A.R., Stamatatos E., Authorship attribution for social media forensics, IEEE Trans. Inf. Forensics Secur, 12, pp. 5-33, (2017); Brennan M., Afroz S., Greenstadt R., Adversarial stylometry: Circumventing authorship recognition to preserve privacy and anonymity, ACM Trans. Inf. Syst. Secur, 15, pp. 1-22, (2012); Fridman L., Weber S., Greenstadt R., Kam M., Active authentication on mobile devices via stylometry, application usage, web browsing, and GPS location, IEEE Syst. J, 11, pp. 513-521, (2017); Iqbal F., Binsalleeh H., Fung B.C.M., Debbabi M., Mining writeprints from anonymous e-mails for forensic investigation, Digit. Investig, 7, pp. 56-64, (2010); Cobo M.J., Lopez-Herrera A.G., Herrera-Viedma E., Herrera F., An approach for detecting, quantifying, and visualizing the evolution of a research field: A practical application to the fuzzy sets theory field, J. Informetrics, 5, pp. 146-166, (2011); Stamatatos E., A survey of modern authorship attribution methods, J. Am. Soc. Inf. Sci. Technol, 60, pp. 538-556, (2009); Juola P., Authorship Attribution, Found. Trends Inf. Retr, 1, pp. 233-334, (2006); Koppel M., Schler J., Argamon S., Computational methods in authorship attribution, J. Am. Soc. Inf. Sci. Technol, 60, pp. 9-26, (2009); Mosteller F., Wallace D.L., Inference and Disputed Authorship: The Federalist, (1964); Mendenhall T.C., The characteristic curves of composition, Science, 11, pp. 237-249, (1887); Zheng R., Li J., Chen H., Huang Z., A framework for authorship identification of online messages: Writing-style features and classification techniques, J. Am. Soc. Inf. Sci. Technol, 57, pp. 378-393, (2006); Abbasi A., Chen H., Applying authorship analysis to extremist-group Web forum messages, IEEE Intell. Syst, 20, pp. 67-75, (2005)","P.D. Michailidis; Department of Balkan, Slavic and Oriental Studies, University of Macedonia, Thessaloniki, 54636, Greece; email: pmichailidis@uom.edu.gr","","MDPI","","","","","","22279709","","","","English","Informatics","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85138709983" -"Norouzi M.; Chàfer M.; Cabeza L.F.; Jiménez L.; Boer D.","Norouzi, Masoud (57223850337); Chàfer, Marta (57193771299); Cabeza, Luisa F. (7004085845); Jiménez, Laureano (56600689900); Boer, Dieter (7003615369)","57223850337; 57193771299; 7004085845; 56600689900; 7003615369","Circular economy in the building and construction sector: A scientific evolution analysis","2021","Journal of Building Engineering","44","","102704","","","","333","10.1016/j.jobe.2021.102704","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106921728&doi=10.1016%2fj.jobe.2021.102704&partnerID=40&md5=91b0c3f029e10e16e3f3952e38d60d47","Departament d'Enginyeria Química, Universitat Rovira i Virgili, Av. Paisos Catalans, 26, Tarragona, 43007, Spain; GREiA Research Centre, Universitat de Lleida, Pere de Cabrera s/n, Lleida, 25001, Spain; CIRIAF - Interuniversity Research Centre, University of Perugia, Via G. Duranti 67, Perugia, 06125, Italy; Departament d'Enginyeria Mecànica, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain","Norouzi M., Departament d'Enginyeria Química, Universitat Rovira i Virgili, Av. Paisos Catalans, 26, Tarragona, 43007, Spain; Chàfer M., GREiA Research Centre, Universitat de Lleida, Pere de Cabrera s/n, Lleida, 25001, Spain, CIRIAF - Interuniversity Research Centre, University of Perugia, Via G. Duranti 67, Perugia, 06125, Italy; Cabeza L.F., GREiA Research Centre, Universitat de Lleida, Pere de Cabrera s/n, Lleida, 25001, Spain; Jiménez L., Departament d'Enginyeria Química, Universitat Rovira i Virgili, Av. Paisos Catalans, 26, Tarragona, 43007, Spain; Boer D., Departament d'Enginyeria Mecànica, Universitat Rovira i Virgili, Av. Paisos Catalans 26, Tarragona, 43007, Spain","The building industry is responsible for considerable environmental impacts due to its consumption of resources and energy, and the production of wastes. Circular Economy (CE), a new paradigm can significantly improve the sustainability of this sector. This paper performs a quantitative scientific evolution analysis of the application of CE in the building sector to detect new trends and highlight the evolvement of this research topic. Around 7000 documents published 2005 to 2020 at Web of Science and Scopus were collected and analyzed. The bibliometric indicators, network citation, and multivariate statistical analysis were obtained using Bibliometrix R-package and VOSviewer. The co-occurrence analysis showed five keyword-clusters, in which the three main ones are: (i) energy and energy efficiency in buildings; (ii) recycling, waste management and alternative construction materials; (iii) sustainable development. The analysis showed that researchers pay close attention to “sustainability”, “energy efficiency”, “life cycle assessment”, “renewable energy”, and “recycling” in the past five years. This paper highlights that (i) the development and use of alternative construction materials; (ii) the development of circular business models; (iii) smart cities, Industry 4.0 and their relations with CE, are the current research hotspots that may be considered as potential future research topics. © 2021 The Author(s)","Bibliometric analysis; Building; Circular economy; Construction sector; Science mapping; Sustainable development","Building materials; Buildings; Construction; Energy efficiency; Environmental impact; Life cycle; Multivariant analysis; Planning; Recycling; Sustainable development; Waste management; Bibliometrics analysis; Building and construction; Buildings sector; Circular economy; Construction sectors; Energy; Evolution analysis; Research topics; Science mapping; Scientific evolution; Construction industry","","","","","Ministerio de Ciencia, Innovación y Universidades, MCIU; Institució Catalana de Recerca i Estudis Avançats, ICREA; European Regional Development Fund, ERDF; Agencia Estatal de Investigación, AEI, (RED2018-102431-T); Agencia Estatal de Investigación, AEI; University of the East, UE, (CTQ2016-77968-C3-1-P); University of the East, UE; Generalitat de Catalunya, (2017-SGR-1409, 2017-SGR-1537, 2019 FI-B-00762); Generalitat de Catalunya; UK Research and Innovation, UKRI, (104787); UK Research and Innovation, UKRI; Ministerio de Economía y Competitividad, MINECO, (RTI2018-093849-B-C33, RTI2018-093849-B-C31); Ministerio de Economía y Competitividad, MINECO","The authors would like to acknowledge financial support from the Spanish Ministry of Economy and Competitiveness RTI2018-093849-B-C33 ( MCIU/AEI/FEDER , UE), RTI2018-093849-B-C31 ( MCIU/AEI/FEDER , UE) and CTQ2016-77968-C3-1-P ( MINECO/FEDER ) and thank the Catalan Government ( 2017-SGR-1409 , 2017-SGR-1537 , and 2019 FI-B-00762 ). This work was partially funded by the Ministerio de Ciencia, Innovaci\u00F3n y Universidades - Agencia Estatal de Investigaci\u00F3n (AEI) ( RED2018-102431-T ). GREiA is a certified agent TECNIO in the category of technology developers from the Government of Catalonia. This work is partially supported by ICREA under the ICREA Academia programme . ","Zuo J., Zhao Z.Y., Green building research-current status and future agenda: a review, Renew. Sustain. Energy Rev., (2014); The European Construction Sector, (2016); Zhao X., Zuo J., Wu G., Huang C., A bibliometric review of green building research 2000–2016, Architect. Sci. Rev., 62, pp. 74-88, (2019); 2019 Global Status Report for Buildings and Construction, (2019); Perez-Lombard L., Ortiz J., Pout C., A Review on Buildings Energy Consumption Information, (2008); Allouhi A., El Fouih Y., Kousksou T., Jamil A., Zeraouli Y., Mourad Y., Energy consumption and efficiency in buildings: current status and future trends, J. Clean. 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A systematic review of the literature, Sustain. Cities Soc., (2019); Bibri S.E., Krogstie J., Smart sustainable cities of the future: an extensive interdisciplinary literature review, Sustain. Cities Soc., (2017); Del Borghi A., Gallo M., Strazza C., Castagna M., Waste management in smart Cities : the application of circular economy in genoa, impresa progett. 0 electron, J. Manag., (2014); Esa M.R., Halog A., Rigamonti L., Developing strategies for managing construction and demolition wastes in Malaysia based on the concept of circular economy, J. Mater. Cycles Waste Manag., (2017); Haas W., Krausmann F., Wiedenhofer D., Heinz M., How circular is the global economy?: an assessment of material flows, waste production, and recycling in the European Union and the world in 2005, J. Ind. Ecol., 19, pp. 765-777, (2015)","D. Boer; Department of Mechanical Engineering, Universitat Rovira i Virgili, Tarragona, Av. Països Catalans, 26, 43007, Spain; email: dieter.boer@urv.cat","","Elsevier Ltd","","","","","","23527102","","","","English","J. Build. Eng.","Article","Final","All Open Access; Green Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-85106921728" -"Fatma N.; Haleem A.","Fatma, Nosheen (57222530204); Haleem, Abid (25627604500)","57222530204; 25627604500","Exploring the Nexus of Eco-Innovation and Sustainable Development: A Bibliometric Review and Analysis","2023","Sustainability (Switzerland)","15","16","12281","","","","34","10.3390/su151612281","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85168965484&doi=10.3390%2fsu151612281&partnerID=40&md5=fc49af2607408acb42c513d3f7927965","Department of Mechanical Engineering, Jamia Millia Islamia, New Delhi, 110025, India","Fatma N., Department of Mechanical Engineering, Jamia Millia Islamia, New Delhi, 110025, India; Haleem A., Department of Mechanical Engineering, Jamia Millia Islamia, New Delhi, 110025, India","Eco-innovation promotes sustainable economic growth while mitigating environmental impacts. It has evolved into an essential tool for firms seeking to align with the 2030 Sustainable Development Goals. A total of 723 articles from Web of Science and Scopus databases were analyzed in the timespan of 2001–2022 to unveil the contributions and interconnections among eco-innovation, sustainable development, and the SDGs. This study aims to conduct a comprehensive performance analysis and science mapping using Bibliometrix R-package and VosViewer, respectively. The analysis highlights the influential authors, journals, countries, and thematic trends of research articles. The trend analysis shows that carbon emission limitation, targeting SDGs in isolation, and environmental economics are gradually becoming mainstream. Eco-innovation’s transformative potential spans economic, social, and environmental dimensions of sustainable development, though its studies have primarily focused on its environmental implications. This can offer new research directions to researchers and will be beneficial for framework development. © 2023 by the authors.","eco-innovation; network analysis; PRISMA; science mapping; sustainable development goals","carbon emission; database; economic growth; environmental economics; innovation; network analysis; sustainable development; trend analysis","","","","",", (103466)","","Diaz-Garcia C., Gonzalez-Moreno A., Saez-Martiinez F.J., Eco-innovation: Insights from a literature review, Innovation, 17, pp. 6-23, (2015); Nylund P.A., Agarwal N., Probst C., Brem A., Firm engagement in UN Sustainable Development Goals: Introduction of a constraints map from a corporate reports content analysis, J. Clean. Prod, 371, (2022); Horbach J., Rammer C., Rennings K., Determinants of eco-innovations by type of environmental impact—The role of regulatory push/pull, technology push and market pull, Ecol. 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Fatma; Department of Mechanical Engineering, Jamia Millia Islamia, New Delhi, 110025, India; email: nosheenfatma131@gmail.com","","Multidisciplinary Digital Publishing Institute (MDPI)","","","","","","20711050","","","","English","Sustainability","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85168965484" -"Song G.; Wu J.; Wang S.","Song, Guandong (55370450600); Wu, Jiying (57220178489); Wang, Sihui (57220182818)","55370450600; 57220178489; 57220182818","Text Mining in Management Research: A Bibliometric Analysis","2021","Security and Communication Networks","2021","","2270276","","","","14","10.1155/2021/2270276","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120846264&doi=10.1155%2f2021%2f2270276&partnerID=40&md5=bd69987b8d8ab984529acb1dc39472c5","School of Humanities and Law, Northeastern University, Liaoning, Shenyang, 110167, China; School of Music, Soochow University, Suzhou, 215127, China","Song G., School of Humanities and Law, Northeastern University, Liaoning, Shenyang, 110167, China; Wu J., School of Humanities and Law, Northeastern University, Liaoning, Shenyang, 110167, China; Wang S., School of Music, Soochow University, Suzhou, 215127, China","The goal of this paper is to provide a bibliometric analysis of scientific publications that employ text mining in management. To accomplish this, the authors collected 1282 documents from the Web of Science and performed performance analysis and science mapping with the help of the Bibliometrix package in Rstudio. The performance analysis used a range of bibliometric indicators such as productivity, citations, h-index, and m-quotient, in order to identify research trends and the most influential journals, authors, countries, and literature in the study. Science mapping used author keywords co-occurrence, co-authorship, and co-citation analysis to reflect the conceptual, social, and intellectual structure of the research. Specifically, we have seen an exponential increase in the use of text mining in management in recent years. The United States is the dominant country for research, having the earliest studies and the highest number of literature and citations. Furthermore, the research themes showed that topic modeling is at the forefront of current text mining research about management. This study will help scholars and management practitioners interested in the intersection of text mining and management to quickly understand the latest advances in research. © 2021 Guandong Song et al.","","Data mining; Bibliometric indicators; Bibliometrics analysis; Co-occurrence; H indices; Management research; Performances analysis; Research trends; Scientific publications; Text-mining; Web of Science; Mapping","","","","","","","Poldrack R.A., Mumford J.A., Nichols T.E., The Text Mining Handbook, (2007); Zong C., Xia R., Zhang J., Text Data Mining, (2021); Grobelnik M., Mladenic D., Jermol M., Exploiting Text Mining in Publishing and Education, pp. 34-39; Miner G., Elder I.V.J., Fast A., Hill T., Nisbet R., Delen D., Practical Text Mining and Statistical Analysis for Non-structured Text Data Applications, (2012); Luhn H.P., The automatic creation of literature abstracts, IBM Journal of Research and Development, 2, 2, pp. 159-165, (1958); Doyle L.B., Semantic road maps for literature searchers, Journal of the ACM, 8, (1961); 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Dong L.Y., Ji S.J., Zhang C.J., Zhang Q., Chiu D.W., Qiu L.Q., Li D., An unsupervised topic-sentiment joint probabilistic model for detecting deceptive reviews, Expert Systems with Applications, 114, pp. 210-223, (2018); Wang J., Hsu C.C., A topic-based patent analytics approach for exploring technological trends in smart manufacturing, Journal of Manufacturing Technology Management, 32, 1, pp. 110-135, (2020); Zhou L., Zhang L., Zhao Y., Zheng R., Song K., A scientometric review of blockchain research, Information Systems and E-Business Management, pp. 1-31, (2020); Cahlik T., Comparison of the maps of science, Scientometrics, 49, 3, pp. 373-387, (2000); Zhai H.K., Li Q., Wei X.W., Research topics and evolution paths in the field of international mental health literacy from 2009 to 2018, Journal of Southwest University for Nationalities, 42, 3, (2021); Yu Y., Duan W., Cao Q., The impact of social and conventional media on firm equity value: A sentiment analysis approach, Decision Support Systems, 55, 4, pp. 919-926, (2013); Nassirtoussi A.K., Aghabozorgi S., Wah T.Y., Ngo D., Text mining for market prediction: A systematic review, Expert Systems with Applications, 41, 16, pp. 7653-7670, (2014); Abrahams A.S., Fan W., Wang G.A., Zhang Z.J., Jiao J., An integrated text analytic framework for product defect discovery, Production and Operations Management, 24, 6, pp. 975-990, (2015)","J. Wu; School of Humanities and Law, Northeastern University, Shenyang, Liaoning, 110167, China; email: lilylove10@21cn.com","","Hindawi Limited","","","","","","19390114","","","","English","Secur. Commun. Networks","Article","Final","All Open Access; Gold Open Access","Scopus","2-s2.0-85120846264" -"Moradi E.; Gholampour S.; Gholampour B.","Moradi, Erfan (57215671451); Gholampour, Sajad (57215435398); Gholampour, Behzad (57215411588)","57215671451; 57215435398; 57215411588","Past, present and future of sport policy: a bibliometric analysis of International Journal of Sport Policy and Politics (2010–2022)","2023","International Journal of Sport Policy and Politics","15","4","","577","602","25","10","10.1080/19406940.2023.2228829","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163685299&doi=10.1080%2f19406940.2023.2228829&partnerID=40&md5=ff3929b70af8206e51e9e557f1273ab0","Department of Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran; Parseh iMetrics Institute, Tehran, Iran","Moradi E., Department of Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran; Gholampour S., Parseh iMetrics Institute, Tehran, Iran; Gholampour B., Parseh iMetrics Institute, Tehran, Iran","Understanding a discipline’s literature is essential to advance in that area. However, there has yet to be a study that summarises the current research on sport policy. Without a study of the topic, particularly one as extensive as the current one, where over 450 papers were evaluated, it is difficult for newcomers to the field and seasoned experts to have a firm grasp of all there is to know about it. Given this context, the current research is necessary and valuable because it is the first to provide insight into the effectiveness and intellectual framework of the sport policy literature selected by the International Journal of Sport Policy and Politics (IJSPP). This study used bibliometric techniques and indicators to analyse IJSPP publications from 2010 to 2022. The research data was collected from Scopus and analysed with bibliometrix and VOSviewer software. We found that the various components of the production (countries, institutions, and authors) in IJSPP work well in collaboration and over 82% of the research results from teamwork. The co-occurrence analysis of keywords comprises nine clusters, the co-citation analysis comprises four, and sport policy was the most significant cluster. Looking at niche topics in the future, sports diplomacy, social justice, elite sport policy, sport for development, and youth sport are just a few of the niche themes that have the potential to come up. This study will be helpful as a roadmap for researchers in different fields who are interested in such studies, as well as for editorial board members and those who work in sport policy and politics. © 2023 Informa UK Limited, trading as Taylor & Francis Group.","Bibliometric analysis; intellectual structure; International Journal of Sport Policy and Politics; science mapping; Scopus; sport policy","","","","","","","","Andrade D.C., Et al., Bibliometric analysis of South American research in sports science from 1970 to 2012, Motriz: Revista de Educação Física, 19, 4, pp. 783-791, (2013); Aquilina D., Henry I., Elite athletes and university education in Europe: a review of policy and practice in higher education in the European Union Member States, International Journal of Sport Policy & Politics, 2, 1, pp. 25-47, (2010); Aria M., Cuccurullo C., Bibliometrix: an R-tool for comprehensive science mapping analysis, Journal of informetrics, 11, 4, pp. 959-975, (2017); Baier-Fuentes H., Et al., Emotions and sport management: a bibliometric overview, Frontiers in psychology, 11, (2020); 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A bibliometric analysis of the state of policy research on medical tourism, Global health research and policy, 5, 1, pp. 1-16, (2020); Walker C.M., Hayton J.W., An analysis of third sector sport organisations in an era of ‘super-austerity’, International Journal of Sport Policy & Politics, 10, 1, pp. 43-61, (2018); Wei F., Zhang G., Exploring the intellectual structure and evolution of 24 top business journals: a scientometric analysis, The electronic library, 38, 3, pp. 493-511, (2020); Wickman K., The governance of sport, gender and (dis) ability, International Journal of Sport Policy & Politics, 3, 3, pp. 385-399, (2011); Wilson M.L., Topics, author profiles, and collaboration networks in the Journal of Research on Technology in Education: a bibliometric analysis of 20 years of research, Journal of research on technology in education, pp. 1-23, (2022); Wolfe S.D., ‘For the benefit of our nation’: unstable soft power in the 2018 men’s World Cup in Russia, International Journal of Sport Policy & Politics, 12, 4, pp. 545-561, (2020); Yamanaka G.K., Et al., eSport: a state-of-the-art review based on bibliometric analysis, Journal of physical education and sport, 21, 6, pp. 3547-3555, (2021); Yihua W., Et al., Twelve years of research in the International Journal of Islamic and Middle Eastern Finance and Management: a bibliometric analysis, International Journal of Islamic & Middle Eastern Finance & Management, 16, 1, pp. 154-174, (2023); Zahra A.A., Et al., Bibliometric analysis of trends in theory-related policy publications, Emerging science journal, 5, 1, pp. 96-110, (2021); Zelenkov Y., Solntsev I., Analysis of research dynamics in sport management using topic modelling, Managing sport and leisure, pp. 1-22, (2023); Zhang B., Research on the development and change of Chinese sports science based on bibliometric analysis, Eurasia journal of mathematics, science and technology education, 13, 10, pp. 6407-6414, (2017)","E. Moradi; Department of Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran; email: erfan.moradi@modares.ac.ir","","Routledge","","","","","","19406940","","","","English","Int. J. Sport Policy","Article","Final","","Scopus","2-s2.0-85163685299" -"Hu L.; Yang J.; Liu T.; Zhang J.; Huang X.; Yu H.","Hu, Liyu (57216179019); Yang, Jikang (58693521600); Liu, Ting (58603600700); Zhang, Jinhuan (57221656192); Huang, Xingxian (56900054000); Yu, Haibo (25651230000)","57216179019; 58693521600; 58603600700; 57221656192; 56900054000; 25651230000","Hotspots and Trends in Research on Treating Pain with Electroacupuncture: A Bibliometric and Visualization Analysis from 1994 to 2022","2023","Journal of Pain Research","16","","","3673","3691","18","2","10.2147/JPR.S422614","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85176551112&doi=10.2147%2fJPR.S422614&partnerID=40&md5=f5bbd1e6c46a6814ea8ed5783cd43b91","The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Shenzhen, China","Hu L., The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Shenzhen, China; Yang J., The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Shenzhen, China; Liu T., The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Shenzhen, China; Zhang J., The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Shenzhen, China; Huang X., The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Shenzhen, China; Yu H., The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Shenzhen, China","Purpose: Electroacupuncture is widely used to pain management. A bibliometric analysis was conducted to identify the hotspots and trends in research on electroacupuncture for pain. Methods: We retrieved studies published from 1994–2022 on the topic of pain relief by electroacupuncture from the Web of Science Core Collection database. We comprehensively analysed the data with VOSviewer, CiteSpace, and bibliometrix. Seven aspects of the data were analysed separately: annual publication outputs, countries, institutions, authors, journals, keywords and references. Results: A total of 2030 papers were analysed, and the number of worldwide publications continuously increased over the period of interest. The most productive country and institution in this field were China and KyungHee University. Evidence-Based Complementary and Alternative Medicine was the most productive journal, and Pain was the most co-cited journal. Han Jisheng, Fang Jianqiao, and Lao Lixing were the most representative authors. Based on keywords and references, three active areas of research on EA for pain were mechanisms, randomized controlled trials, and perioperative applications. Three emerging trends were functional magnetic resonance imaging (fMRI), systematic reviews, and knee osteoarthritis. Conclusion: This study comprehensively analysed the research published over the past 28 years on electroacupuncture for pain treatment, using bibliometrics and science mapping analysis. This work presents the current status and landscape of the field and may serve as a valuable resource for researchers. Chronic pain, fMRI-based mechanistic research, and the perioperative application of electroacupuncture are among the likely foci of future research in this area. © 2023 Hu et al. This work is published and licensed by Dove Medical Press Limited.","bibliometrics; blibliometrix; CiteSpace; electroacupuncture; pain; VOSviewer","acupuncture; alternative medicine; analgesia; anxiety; Article; Australia; bibliometrics; China; data visualization; depression; electroacupuncture; functional magnetic resonance imaging; human; hysterectomy; immunocytochemistry; knee osteoarthritis; Korea; low back pain; nociception; nonhuman; pain; postoperative pain; publication; randomized controlled trial (topic); systematic review; United Kingdom; United States","","","","","Shenzhen’s Sanming Project, (SZSM201612001)","This work was supported by Shenzhen’s Sanming Project (SZSM201612001).","Raja SN, Carr DB, Cohen M, Et al., The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises, Pain, 161, 9, pp. 1976-1982, (2020); Orr PM, Shank BC, Black AC., The role of pain classification systems in pain management, Crit Care Nurs Clin North Am, 29, 4, pp. 407-418, (2017); 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Yu; The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, No. 1 Fuhua Road, Futian District, 518000, China; email: 13603066098@163.com","","Dove Medical Press Ltd","","","","","","11787090","","","","English","J. Pain Res.","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85176551112" -"Secinaro S.; Calandra D.; Petricean D.; Chmet F.","Secinaro, Silvana (57044744300); Calandra, Davide (57212495726); Petricean, Denisa (53980405600); Chmet, Federico (57219385843)","57044744300; 57212495726; 53980405600; 57219385843","Social finance and banking research as a driver for sustainable development: A bibliometric analysis","2021","Sustainability (Switzerland)","13","1","330","1","18","17","51","10.3390/su13010330","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099025763&doi=10.3390%2fsu13010330&partnerID=40&md5=2f2d40b0e156c4d1cdd8fe8c01b85ebc","Department of Management, University of Turin, Turin, 10134, Italy; Brunel University London, London, UB8 3PH, United Kingdom","Secinaro S., Department of Management, University of Turin, Turin, 10134, Italy; Calandra D., Department of Management, University of Turin, Turin, 10134, Italy; Petricean D., Brunel University London, London, UB8 3PH, United Kingdom; Chmet F., Department of Management, University of Turin, Turin, 10134, Italy","Social finance and banking with an embedded social purpose have been on the rise in recent decades. Social entrepreneurs have repeatedly stressed the critical need for financial support from social banks. This study aims to provide a bibliometric analysis of the status of the field in social finance and banking, recognising main topics from existing research and establishing future re-search challenges. Our study used science mapping workflow and multiple research questions to investigate the broad literature about social banking and finance. With in-depth bibliometric analysis, authors examined qualitative and quantitative variables as primary research infor-mation, relevant sources, subject areas, authors data, social, thematic and intellectual structure. The data was retrieved from Web of Science (WOS) and then analysed using Bibliometrix R-package. The analysis was based on a sample of 270 articles and demonstrates a multidisciplinary vision of the research flow investigated. Our results show several insights regarding journals, authors and geographical interest of this research stream. Specifically, the literature, although dwelling on social finance and banking, includes five theoretical and practical clusters as (1) people’s well-being, combined with technological innovation, (2) governance, (3) ethical investment and sustainable development, (4) corporate social responsibility (CSR), and (5) transparency. The authors also note a line of research that observes technological solutions for the response to social and environmental problems. These results may be useful for researchers, practitioners, and policymakers to foster social finance and financial system tools. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.","Bibliometric analysis; Social banking; Social finance; Sustainable development","banking; corporate social responsibility; entrepreneur; financial system; investment; sustainability; sustainable development","","","","","","","Bishop M., Green M., Philanthrocapitalism: How Giving Can Save the World, (2010); Emerson J., Spitzer J., From Fragmentation to Function: Critical Concepts and Writing on Social Capital Markets’ Structure, Operation and Innovation, (2007); Nicholls A., The Legitimacy of Social Entrepreneurship: Reflexive Isomorphism in a Pre-Paradigmatic Field, Entrep. Theory Pract, 34, pp. 611-633, (2010); Weber O., Duan Y., Social Finance and Banking, Socially Responsible Finance and Investing: Financial Institutions, Corporations, Investors, and Activists, 160, (2012); Perilleux A., When Social Enterprises Engage in Finance: Agents of Change in Lending Relationships, a Belgian Typology, Strateg. 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A Case Study from the Gas Fields of Wyoming, J. Rural Stud, 43, pp. 235-247, (2016); Munoz de Prat J., Escriva-Beltran M., Gomez-Calvet R., Joint Ventures and Sustainable Development. A Bibliometric Analysis, Sustainability, 12, (2020)","D. Calandra; Department of Management, University of Turin, Turin, 10134, Italy; email: davide.calandra@unito.it","","MDPI","","","","","","20711050","","","","English","Sustainability","Article","Final","All Open Access; Gold Open Access; Green Open Access","Scopus","2-s2.0-85099025763" -"Khan F.M.; Anas M.; Uddin S.M.F.","Khan, Fateh Mohd (58143325900); Anas, Mohammad (57217379967); Uddin, S. M. Fatah (57192435998)","58143325900; 57217379967; 57192435998","Anthropomorphism and consumer behaviour: A SPAR-4-SLR protocol compliant hybrid review","2024","International Journal of Consumer Studies","48","1","e12985","","","","33","10.1111/ijcs.12985","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85172167248&doi=10.1111%2fijcs.12985&partnerID=40&md5=0050845c5055c29edcd28ed7cc2b10a9","Department of Business Administration, Aligarh Muslim University, Aligarh, India; Department of Marketing, Birla Institute of Management Technology, Greater Noida, India","Khan F.M., Department of Business Administration, Aligarh Muslim University, Aligarh, India; Anas M., Department of Business Administration, Aligarh Muslim University, Aligarh, India; Uddin S.M.F., Department of Marketing, Birla Institute of Management Technology, Greater Noida, India","The notion of ‘anthropomorphism’ has been a subject of intrigue for transdisciplinary academics and scholars for the longest time, as the origin of this concept dates back to the BCE (Before Common Era). Over the past few decades, anthropomorphism literature has been burgeoning in the marketing discipline and its subfields (branding, advertising, consumer behaviour, etc.). This relatively novel stream adopts anthropomorphism as a concept and offers fascinating insights into consumers and their choices, behaviour, and intentions. Although there have been several qualitative review-based assessments of anthropomorphism within the marketing field, none have been informed by quantitative tools or through a framework-based approach. Our hybrid variant of systematic review fills this gap by using bibliometric techniques (performance analysis, co-authorship analysis of countries and authors, and co-word analysis of keywords) and Theories-Context-Characteristics-Methods (TCCM) framework to show the evolution, trends, and intellectual structure of anthropomorphism in consumer behaviour research. We depict the evolving trajectory and trends over time using a sample of 432 peer-reviewed journal articles and 27,671 secondary references (between 2005 and 2023) on anthropomorphism in consumer behaviour. Significant results include identifying and describing the most influential authors, articles, journals and countries, different research streams, their development, and future research directions. We also present six knowledge clusters delineating the intellectual knowledge structure of the field. An additional section depicting theories employed, characteristics explored, contexts examined, and methods utilized in the domain have also been presented. Furthermore, we used the TCCM framework to orchestrate possible trajectories for future research. By doing this, we offer academics and practitioners a systematic comprehension of the advancements in the domain and a comprehensive road map for future research. © 2023 John Wiley & Sons Ltd.","anthropomorphism; Bibliometrix-R; consumer behaviour; science mapping; TCCM framework; VOSviewer","","","","","","","","Aaker J.L., Dimensions of brand personality, Journal of Marketing Research, 34, 3, pp. 347-356, (1997); Adam M., Wessel M., Benlian A., AI-based chatbots in customer service and their effects on user compliance, Electronic Markets, 31, 2, pp. 427-445, (2021); Aggarwal P., McGill A.L., Is that car smiling at me? Schema congruity as a basis for evaluating anthropomorphized products, Journal of Consumer Research, 34, 4, pp. 468-479, (2007); Aggarwal P., Mcgill A.L., When brands seem human, do humans act like brands? 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Stud.","Review","Final","","Scopus","2-s2.0-85172167248" -"Vit P.; Ekundayo T.C.; Wang Z.","Vit, Patricia (6604081206); Ekundayo, Temitope Cyrus (57204841448); Wang, Zhengwei (36168639400)","6604081206; 57204841448; 36168639400","MAPPING SIX DECADES OF STINGLESS BEE HONEY RESEARCH: CHEMICAL QUALITY AND BIBLIOMETRICS; [MAPEANDO SEIS DÉCADAS DE PESQUISA EM MEL DE ABELHAS SEM FERRÃO: QUALIDADE QUÍMICA E BIBLIOMETRIA]; [MAPEO DE SEIS DÉCADAS DE INVESTIGACIÓN EN MIEL DE ABEJAS SIN AGUIJÓN: CALIDAD QUÍMICA Y BIBLIOMETRÍA]","2023","Interciencia","48","8","","380","387","7","3","","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85171531867&partnerID=40&md5=db39dec29620b64651770b9fea0c6525","Cardiff University, United Kingdom; Universidad de Los Andes (ULA), Mérida, Venezuela; Apitherapy and Bioactivity, Food Science Department, Faculty of Pharmacy and Bioanalysis, Universidad de Los Andes, Mérida, Venezuela; University of Fort Hare, South Africa; Department of Biotechnology and Food Science, Durban University of Technology, Steve Biko Campus, Durban, South Africa; Department of Microbiology, University of Medical Sciences, Ondo, Nigeria; Yunnan Agricultural University, China; CAS, Key Laboratory of Tropical Forest Ecology, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, China","Vit P., Cardiff University, United Kingdom, Universidad de Los Andes (ULA), Mérida, Venezuela, Apitherapy and Bioactivity, Food Science Department, Faculty of Pharmacy and Bioanalysis, Universidad de Los Andes, Mérida, Venezuela; Ekundayo T.C., University of Fort Hare, South Africa, Department of Biotechnology and Food Science, Durban University of Technology, Steve Biko Campus, Durban, South Africa, Department of Microbiology, University of Medical Sciences, Ondo, Nigeria; Wang Z., Yunnan Agricultural University, China, CAS, Key Laboratory of Tropical Forest Ecology, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, China","Stingless bees (Apidae: Apinae: Meliponini) process honey in cerumen pots, thus it is called pot-honey. Almost 600 species of stingless bees produce tropical pot-honey. Despite the Codex Alimentarius Commission neglecting the international regulation of this relevant meliponine product, local and national regulations are growing since 2014. Besides the higher water content and free acidity, a recent discovery of the sugar trehalulose in pot-honey is one more distinctive trait. The great entomological biodiversity has an impact on chemical composition and bioactivity of the honey, as well as the botanical origin which has been less studied due to the vast number of stingless bee species compared to the unique Apis mellifera. A bibliometric review (1962-2022) was conducted to analyze the evolution of stingless bee honey scientific literature, prolific authors, most active institutions, most productive countries, major journals used to disseminate pot-honey research, to identify theme maps and their connections to scientific disciplines using the Scopus database and the bibliometrix software. The taxonomic structure for this bibliometric review was described. In these six decades, a Venezuelan author stood out, Universidad de Los Andes was the third institution with the highest number of publications, and Venezuela ranked as the sixth most productive country after Brazil, Malaysia, Mexico, the United States, and Indonesia. A word cloud, tree map, dendrogram, and conceptual map were visualized. The network of sources and the evolution of authors’ keywords were mapped with VOSviewer. This review was the first comprehensive science mapping analysis of stingless bee honey. © 2023 Interciencia Association. All rights reserved.","Bibliometrics; Chemical Composition; Meliponini; Pot-Honey; Stingless Bee Honey","","","","","","Centro de Submarinismo de la Universidad Simón Bolívar CESUSIBO; Università Politecnica delle Marche, UNIVPM; Universidad de los Andes, Uniandes","To sponsors for the APC, Mr. Giovanni Vit, father of Patricia Vit, who first valued this contribution to innovate stingless bee honey applications in the pharmaceutical science, and Centro de Submarinismo de la Universidad Simón Bolívar CESUSIBO. To worldwide stingless bee keepers, entomologists, and multidisciplinary scientists to make possible research on the chemical quality of pot-honey or stingless bee honey during six decades. To genuine peer reviewers of bibliometric contributions. To Prof. Luis Núñez from Universidad Industrial de Santander, Bucaramanga, Colombia, for his wise advice related to the links of supplementary material. To Universidad de Los Andes, and to Universitá Politecnica delle Marche, Ancona, Italy. To the memory of attentive Father Santiago López-Palacios, the most prolific and versatile book writer of the Faculty of Pharmacy, curious about the chemical quality of honey collected along his fieldwork on the Venezuelan bee flora, that became P. Vit research line.","Agência de Defesa Agropecuária da Bahia. Portaria ADAB nº207 de 21/11/2014, pp. 1-4, (2014); Agência de Defesa Agropecuária e Florestal do Estado do Amazonas. 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Instrução Normativa n◦ 001, de 17 de abril de 2019, pp. 1-7, (2019); Instituto Ecuatoriano de Normalización. Pot-Honey Standard Project in Ecuador, (2015); Jacobs N, Co-term network analysis as a means of describing the information landscapes of knowledge communities across sectors, Journal of Documentation, 58, pp. 548-562, (2022); Lopez-Palacios S, Catálogo para una Flora Apícola Venezolana, (1986); Michener CD, The bees of the world, (2007); Myers L, Top 40 green hex codes for growth, freshness & abundance, (2022); Oromokoma C, Kasangaki P, Akite P, Mugume R, Kajobe R, Mangusho G, Matovu M, Chemurot M, First physicochemical analysis of stingless bee honey from Uganda, Journal of Apicultural Research, (2023); Persano Oddo L, Heard TA, Rodriguez-Malaver A, Perez RA, Fernandez-Muino M, Sancho MT, Sesta G, Lusco L, Vit P, Composition and antioxidant activity of Trigona carbonaria honey from Australia, Journal of Medicinal Food, 11, pp. 789-794, (2008); Popova M, Gerginova D, Trusheva B, Simova S, Tamfu AN, Ceylan O, Clark K, Bankova V, Preliminary study of chemical profiles of honey, cerumen, and propolis of the African stingless bee Meliponula ferruginea, Foods, 10, (2021); Pranckute R, Web of Science (WoS) and Scopus: The titans of bibliographic information in today’s academic world, Publications, 9, (2021); Rowley J, Sbaffi L, Sugden M, Gilbert A, Factors influencing researchers’ journal selection decisions, Journal of Information Science, 48, pp. 321-335, (2022); Secretaria de Estado da Agricultura e da Pesca e do Desenvolvimento Rural, pp. 16-24, (2020); Miel de Tetragonisca fiebrigi (yateí), (2019); Sooklim C, Samakkara W, Thongmee A, Duangphakdee O, Soontorngun N, Enhanced aroma and flavour profile of fermented Tetragonula pagdeni Schwarz honey by a novel yeast T. delbrueckii GT-ROSE1 with superior fermentability, Food Bioscience, 50, (2022); Souza B, Roubik D, Barth O, Heard T, Enriquez E, Carvalho C, Marchini L, Villas-Boas J, Locatelli J, Persano Oddo L, Almeida-Muradian L, Bogdanov S, Vit P, Composition of stingless bee honey: Setting quality standards, Interciencia, 31, pp. 867-875, (2006); Starmer WT, Lachance MA, Yeast ecology, The Yeasts, pp. 65-83, (2011); Tay A, Bibliometrix – A powerful and popular new bibliometric tool used in the domain of business and management, (2022); Van Eck NJ, Waltman L, VOSviewer Manual. Manual for VOSviewer version 1.6.17. Universiteit Leiden & CWTS Meaningful metrics, (2021); Vit P, Modificaciones comentadas de la norma Miel de Abejas, hacia la norma Miel de Venezuela: Inclusión de miel de pote y ex-clusión de mieles falsas, Stingless bees process honey and pollen in cerumen pots, pp. 1-8, (2013); Vit P, The Biodiversity of Neotropical Meliponini in a honey world dominated by Apis mellifera, International Conference for Physical, Life and Health Sciences, (2017); Vit P, A honey authenticity test by interphase emulsion reveals biosurfactant activity and biotechnology in the stingless bee nest of Scaptotrigona vitorum 'Catiana' from Ecuador, Interciencia, 47, pp. 416-425, (2022); Vit P, Proposal of quality standards for Tetragonisca angustula (Latreille, 1811) honey based on data from Brazil, Colombia, Costa Rica, Ecuador, Guatemala, and Venezuela, ICbees International Congress on Bee Sciences, (2023); Vit P, Proposal of quality standards for Tetragonisca Moure, 1946 honey based on Tetragonisca angustula (Latreille, 1811) and Tetragonisca fiebrigi (Schwarz, 1938) honey data from Argentina, Bolivia, Brazil, Colombia, Costa Rica, Ecuador, Guatemala, and Venezuela, pp. 19-23, (2023); Vit P, Chuttong B, Zawawi N, Diaz M, van der Meulen J, Ahmad HF, Tomas-Barberan FA, Meccia G, Danmek K, Moreno JE, Roubik D, Barth OM, Lachenmeier DW, Engel MS, A novel integrative methodology for research on pot-honey variations during post-harvest, Sociobiology, 69, (2022); Vit P, Medina M, Enriquez ME, Quality standards for medicinal uses of Meliponinae honey in Guatemala, Mexico and Venezuela, Bee World, 85, pp. 2-5, (2004); Vit P, Pedro SRM, Maza F, Kunert C, Prospective contribution for Ecuadorian Scaptotrigona pot-honey norm, APIMONDIA International Apicultural Congress, (2017); Vit P, Pedro SRM, Roubik D, Pot-honey. A legacy of stingless bees, (2013); Vit P, Pedro SRM, Roubik D, Pot-pollen in stingless bee melittology, (2018); Vit P, Persano Oddo L, Marano ML, Salas de Mejias E, Venezuelan stingless bee honeys characterised by multivariate analysis of compositional factors, Apidologie, 29, pp. 377-389, (1998); Vit P, Titera D, Evaluación de etiquetas de miel de abejas producida en la República Checa: Una forma de comunicación entre apicultores y consumidores, Vida Apícola, 234, pp. 26-34, (2022); Vit P, van der Meulen J, Pedro SRM, Esperanca I, Zakaria R, Beckh G, Maza F, Meccia G, Engel MS, Impact of genus (Geotrigona, Melipona, Scaptotrigona) in the 1H-NMR organic profile, and authenticity test by interphase emulsion of honey processed in cerumen pots by stingless bees in Ecuador, Current Research in Food Science, 6, (2023); Wille A, A technique for collecting stingless bees under jungle conditions, Insectes Sociaux, 9, pp. 291-293, (1962); Zakaria R, Ahmi A, Ahmad AH, Othman Z, Azman KF, Aziz CBA, Ismail CAN, Shafin N, Visualising and mapping a decade of literature on honey research: a bibliometric analysis from 2011 to 2020, Journal of Apicultural Research, 60, pp. 359-368, (2021); Zawawi N, Zhang J, Hungerford NL, Yates HAS, Webber DC, Farrell M, Tinggi U, Bhandari B, Fletcher MT, Unique physicochemical properties and rare reducing sugar trehalulose mandate new international regulation for stingless bee honey, Food Chemistry, 373, (2022); Zhu J, Liu W, A tale of two databases: The use of Web of Science and Scopus in academic papers, Scientometrics, 123, pp. 321-335, (2020)","","","Interciencia Association","","","","","","03781844","","","","English","Interciencia","Article","Final","","Scopus","2-s2.0-85171531867" -"Aria M.; Alterisio A.; Scandurra A.; Pinelli C.; D’Aniello B.","Aria, Massimo (23388148900); Alterisio, Alessandra (57016882400); Scandurra, Anna (56090826300); Pinelli, Claudia (7003748076); D’Aniello, Biagio (57203148440)","23388148900; 57016882400; 56090826300; 7003748076; 57203148440","The scholar’s best friend: research trends in dog cognitive and behavioral studies","2021","Animal Cognition","24","3","","541","553","12","88","10.1007/s10071-020-01448-2","https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096384169&doi=10.1007%2fs10071-020-01448-2&partnerID=40&md5=31a529becff6afcf931a7a06999936bf","Department of Economics and Statistics, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; Department of Biology, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Caserta, Italy","Aria M., Department of Economics and Statistics, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; Alterisio A., Department of Biology, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; Scandurra A., Department of Biology, University of Naples Federico II, via Cinthia, Naples, 80126, Italy; Pinelli C., Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Caserta, Italy; D’Aniello B., Department of Biology, University of Naples Federico II, via Cinthia, Naples, 80126, Italy","In recent decades, cognitive and behavioral knowledge in dogs seems to have developed considerably, as deduced from the published peer-reviewed articles. However, to date, the worldwide trend of scientific research on dog cognition and behavior has never been explored using a bibliometric approach, while the evaluation of scientific research has increasingly become important in recent years. In this review, we compared the publication trend of the articles in the last 34 years on dogs’ cognitive and behavioral science with those in the general category “Behavioral Science”. We found that, after 2005, there has been a sharp increase in scientific publications on dogs. Therefore, the year 2005 has been used as “starting point” to perform an in-depth bibliometric analysis of the scientific activity in dog cognitive and behavioral studies. The period between 2006 and 2018 is taken as the study period, and a backward analysis was also carried out. The data analysis was performed using “bibliometrix”, a new R-tool used for comprehensive science mapping analysis. We analyzed all information related to sources, countries, affiliations, co-occurrence network, thematic maps, collaboration network, and world map. The results scientifically support the common perception that dogs are attracting the interest of scholars much more now than before and more than the general trend in cognitive and behavioral studies. Both, the changes in research themes and new research themes, contributed to the increase in the scientific production on the cognitive and behavioral aspects of dogs. Our investigation may benefit the researchers interested in the field of cognitive and behavioral science in dogs, thus favoring future research work and promoting interdisciplinary collaborations. © 2020, The Author(s).","Behavior; Behavioral science; Bibliometrix; Cognition; Dog; Science mapping","Animals; Bibliometrics; Cognition; Dogs; Friends; Humans; animal; bibliometrics; cognition; dog; friend; human","","","","","Università degli Studi di Napoli Federico II, UNINA; Polo delle Scienze e delle Tecnologie per la Vita, Università degli Studi di Napoli Federico II; Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, Università degli Studi di Napoli Federico II, DICMaPI","","Allen K., Are pets a healthy pleasure? The influence of pets on blood pressure, Curr Dir Psychol Sci, 12, pp. 236-239, (2003); Arden R., Bensky M.K., Adams M.J., A review of cognitive abilities in dogs. 1911 Through 2016: More individual differences. 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A 25 years bibliometric analysis in business and public administration domains, Scientometrics, 108, pp. 595-611, (2016); D'Aniello B., Scandurra A., Ontogenetic effects on gazing behaviour: a case study of kennel dogs (labrador retrievers) in the impossible task paradigm, Anim Cogn, 19, pp. 565-570, (2016); D'Aniello B., Alterisio A., Scandurra A., Petremolo E., Iommelli M.R., Aria M., What’s the point? Golden and Labrador retrievers living in kennels do not understand human pointing gestures, Anim Cogn, 20, pp. 777-787, (2017); De Battisti F., Salini S., Robust analysis of bibliometric data, Stat Methods Appl, 22, pp. 269-283, (2013); Egghe L., Theory and practise of the g-index, Scientometrics, 69, pp. 131-152, (2006); Falagas M.E., Pitsouni E.I., Malietzis G.A., Pappas G., Comparison of PubMed, Scopus, web of science, and Google scholar: strengths and weaknesses, FASEB J, 22, pp. 338-342, (2008); Fanelli D., Lariviere V., Researchers’ individual publication rate has not increased in a century, PLoS ONE, 11, 3, (2016); Gacsi M., Kara E., Belenyi B., Topal J., Miklosi A., The effect of development and individual differences in pointing comprehension of dogs, Anim Cogn, 12, pp. 471-479, (2009); Hare B., Tomasello M., Human-like social skills in dogs?, Trends Cogn Sci, 9, pp. 439-444, (2005); Hare B., Brown M., Williamson C., Tomasello M., The domestication of social cognition in dogs, Science, 298, pp. 1634-1636, (2002); Head E., Cotman C.W., Milgram N.W., Canine cognition, aging and neuropathology, Prog Neuro-Psychopharmacol Biol Psychiatry, 24, pp. 671-673, (2000); Herzog H., The impact of pets on human health and psychological well-being: fact, fiction, or hypothesis?, Curr Dir Psychol Sci, 20, pp. 236-239, (2011); Hirsch J.E., An index to quantify an individual's scientific research output, PNAS, 102, pp. 16569-16572, (2005); Jones A.C., Gosling S.D., Temperament and personality in dogs (Canis familiaris): a review and evaluation of past research, Appl Anim Behav Sci, 95, pp. 1-53, (2005); Kramer C.K., Mehmood S., Suen R.S., Dog ownership and survival: a systematic review and meta-analysis, Circ Cardiovasc Qual Outcomes, 12, (2019); Kubinyi E., Viranyi Z., Miklosi A., Comparative social cognition: from wolf and dog to humans, Comp Cogn Behav Rev, 2, pp. 26-46, (2007); Kubinyi E., Pongracz P., Miklosi A., Dog as a model for studying conspecific and heterospecific social learning, J Vet Behav, 4, pp. 31-41, (2009); Lancichinetti A., Fortunato S., Community detection algorithms: a comparative analysis, Phys Rev E, 80, (2009); Levine G.N., Allen K., Braun L.T., Christian H.E., Friedmann E., Taubert K.A., Thomas S.A., Wells D.L., Lange R.A., Council on cardiovascular and stroke nursing. 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A new account of dogs’ sensitivity to human actions, Biol Rev Camb Philos Soc, 85, pp. 327-345, (2010); van Eck N.J., Waltman L., Software survey: VOSviewer, a computer program for bibliometric mapping, Scientometrics, 84, pp. 523-538, (2010); van Eck N.J., Waltman L., CitNetExplorer: A new software tool for analyzing and visualizing citation networks, J Informetr, 8, pp. 802-823, (2014); von Bohlen, Halbach O., How to judge a book by its cover? How useful are bibliometric indices for the evaluation of “scientific quality” or “scientific productivity”?, Ann Anat, 193, pp. 191-196, (2011); Wallin J.A., Bibliometric Methods: pitfalls and possibilities, Basic Clin Pharmacol Toxicol, 97, pp. 261-275, (2005); Wang G.D., Zhai W., Yang H., Wang L., Zhong L., Liu Y., Et al., Out of southern East Asia: the natural history of domestic dogs across the world, Cell Res, 26, pp. 21-33, (2016); Wayne R.K., Ostrander E.A., Lessons learned from the dog genome, Trends Genet, 23, pp. 557-567, (2007); Wynne C.D.L., Udell M.A.R., Lord K.A., Ontogeny’s impact on human–dog communication, Anim Behav, 76, pp. e1-e4, (2008); Zhang J., Yu Q., Zheng F., Long C., Lu Z., Duan Z., Comparing keywords plus of WOS and author keywords: a case study of patient adherence research, J Assoc Inf Sci Tech, 67, pp. 967-972, (2016)","B. D’Aniello; Department of Biology, University of Naples Federico II, Naples, via Cinthia, 80126, Italy; email: biagio.daniello@unina.it","","Springer Science and Business Media Deutschland GmbH","","","","","","14359448","","","33219880","English","Anim. Cogn.","Article","Final","All Open Access; Green Open Access; Hybrid Gold Open Access","Scopus","2-s2.0-85096384169" diff --git a/sources/new/THE LENS/lens-export.csv b/sources/new/THE LENS/lens-export.csv deleted file mode 100644 index bde1804fb..000000000 --- a/sources/new/THE LENS/lens-export.csv +++ /dev/null @@ -1,1005 +0,0 @@ -Lens ID,Title,Date Published,Publication Year,Publication Type,Source Title,ISSNs,Publisher,Source Country,Author/s,Abstract,Volume,Issue Number,Start Page,End Page,Fields of Study,Keywords,MeSH Terms,Chemicals,Funding,Source URLs,External URL,PMID,DOI,Microsoft Academic ID,PMCID,Citing Patents Count,References,Citing Works Count,Is Open Access,Open Access License,Open Access Colour -000-092-745-653-032,Scientometric Review of Disability Inclusion in the Workplace,2023-03-09,2023,conference proceedings article,Proceedings of the International Conference on Industrial Engineering and Operations Management,,IEOM Society International,,Neha Kumari; Usha Lenka,"There isn't enough research on people with disabilities (PWD), despite the rise in the number of PWD.Although the amount of information concerning disabilities in the workplace is growing, more research is still needed in this field.This study uses bibliometric analysis to discover the most recent publications.Bibliometrics analysis aids in quantitative and graphical analysis, which offers a better understanding of the literature.The authors conduct a bibliometric analysis of the author's publication, country, topics evolution, and keywords.This will be done using Biblioshiny and a web interface for bibliometrix analysis based on the R package.This program was selected because it creates and presents bibliometric networks more skillfully.The most influential articles and journals are also identified in the study.This article will help the future researchers in identifying the authors for collaboration and important journals for sending novel articles.",,,,,Inclusion (mineral); Computer science; Data science; Psychology; Social psychology,,,,,https://ieomsociety.org/proceedings/2023manila/104.pdf https://doi.org/10.46254/an13.20230104,http://dx.doi.org/10.46254/an13.20230104,,10.46254/an13.20230104,,,0,,3,true,,bronze -000-174-906-032-253,Thoughts on the Global Trends and hotspots of the learning curve for robot-assisted surgery.,2025-06-14,2025,letter,Journal of robotic surgery,18632491; 18632483,Springer Science and Business Media LLC,Germany,Yang Liu; Peng Yu; Xi Xiao; Zhilong Dong,,19,1,291,,,,,,National Natural Science Foundation of China (82160148); National Natural Science Foundation of China (82160148); National Natural Science Foundation of China (82160148); National Natural Science Foundation of China (82160148); Fundamental Research Funds for Central Universities (lzujbky-2023-ct06); Fundamental Research Funds for Central Universities (lzujbky-2023-ct06); Fundamental Research Funds for Central Universities (lzujbky-2023-ct06); Fundamental Research Funds for Central Universities (lzujbky-2023-ct06),,http://dx.doi.org/10.1007/s11701-025-02491-2,40515860,10.1007/s11701-025-02491-2,,,0,002-554-834-643-65X; 014-152-115-605-300; 083-583-247-605-326; 101-864-752-783-651; 106-538-497-301-587; 190-073-356-950-726,0,false,, -000-178-154-013-145,Mapping the research landscape of Covid-19 from social sciences perspective: a bibliometric analysis.,2022-07-06,2022,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Koel Roychowdhury; Radhika Bhanja; Sushmita Biswas,"COVID-19 has emerged as a widely researched topic and the academia has taken interest in the effects of COVID-19 in various sectors of human life and society. Most of the bibliometric research addresses scientific contributions in medicine, health, and virology related topics, with very little emphasis on social sciences. Therefore, to address this gap, a bibliometric analysis of research related to COVID-19 in the subject area of social sciences was performed on selected publications from January 2020 to mid-2021. A total of 9289 articles were analysed to identify major emerging themes of Covid-19 and social sciences and how research collaborations between countries have helped in communicating critical issues to academia. The empirical results indicate the dominance of psychology and business economics subjects in the social sciences sphere, with the emerging themes as psychosocial problems among people, economics, the outbreak of SARS, and discussions on the quality of life in terms of surroundings and environment. The study also suggests that more collaborations between social scientists working in different nations is required to explore the less focussed themes addressing the local challenges of poor nations.",127,8,4547,4568,Social science; Bibliometrics; Dominance (genetics); Sociology; Psychosocial; Coronavirus disease 2019 (COVID-19); Perspective (graphical); Political science; Psychology; Library science; Medicine; Biochemistry; Chemistry; Disease; Pathology; Artificial intelligence; Psychiatry; Computer science; Infectious disease (medical specialty); Gene,Bibliometrics; Coronavirus; Covid-19; Developed nations; Developing nations; Social sciences research,,,,https://link.springer.com/content/pdf/10.1007/s11192-022-04447-x.pdf https://doi.org/10.1007/s11192-022-04447-x,http://dx.doi.org/10.1007/s11192-022-04447-x,35813408,10.1007/s11192-022-04447-x,,PMC9256903,0,002-995-319-690-05X; 003-095-100-474-064; 005-016-743-711-46X; 005-248-265-863-575; 006-350-208-567-355; 007-274-087-240-229; 008-960-931-900-955; 011-253-987-718-963; 017-056-077-624-568; 017-401-318-021-528; 018-559-221-080-181; 019-058-732-880-78X; 019-565-928-239-413; 019-830-944-876-679; 022-888-098-987-299; 023-008-014-451-517; 024-102-392-138-007; 024-711-410-560-425; 024-964-567-189-762; 026-888-554-240-400; 033-257-668-284-789; 035-270-714-569-160; 037-721-488-761-260; 037-790-610-462-571; 038-219-340-916-513; 042-229-634-189-386; 042-808-466-343-087; 043-642-261-893-869; 047-642-610-850-038; 048-721-134-874-363; 050-564-107-473-80X; 051-187-074-169-945; 052-010-055-378-517; 058-428-455-994-374; 059-024-588-177-98X; 061-597-443-654-060; 065-230-853-223-233; 069-960-695-750-061; 073-095-700-039-380; 079-334-419-365-321; 081-722-003-753-079; 086-716-103-581-017; 087-079-713-768-791; 092-632-947-732-048; 093-035-698-142-311; 094-048-769-166-089; 098-734-297-961-484; 100-737-959-060-567; 104-096-429-129-49X; 108-633-170-184-911; 108-844-639-299-477; 111-996-636-948-305; 116-019-947-320-768; 133-343-329-650-437; 133-495-109-324-894; 148-620-046-425-114; 157-092-273-721-845,17,true,,bronze -000-330-116-009-245,"Correction to: Past, ongoing, and future debate on the interplay between internationalization and digitalization",2021-05-03,2021,journal article,Journal of Management and Governance,13853457; 1572963x,Springer Science and Business Media LLC,Netherlands,Mara Bergamaschi; Cristina Bettinelli; Elena Lissana; Pasquale Massimo Picone,,25,4,1033,1033,Political science; Economic geography; Internationalization,,,,,https://link.springer.com/content/pdf/10.1007/s10997-021-09576-8.pdf https://link.springer.com/article/10.1007/s10997-021-09576-8 https://ideas.repec.org/a/kap/jmgtgv/v25y2021i4d10.1007_s10997-021-09576-8.html,http://dx.doi.org/10.1007/s10997-021-09576-8,,10.1007/s10997-021-09576-8,3158980400,,0,013-507-404-965-47X,0,true,,bronze -000-555-959-807-031,An overview of global research landscape in etiology of urolithiasis based on bibliometric analysis.,2023-04-17,2023,journal article,Urolithiasis,21947236; 21947228,Springer Science and Business Media LLC,Germany,Caitao Dong; Chao Song; Ziqi He; Wenbiao Liao; Qianlin Song; Yunhe Xiong; Lingchao Meng; Sixing Yang,,51,1,71,,Etiology; Web of science; Medicine; Bibliometrics; Library science; Internal medicine; Meta-analysis; Computer science,Bibliometric analysis; Hypercalciuria; Pathogenesis; Randall’s plaque; Urolithiasis,"Humans; Bibliometrics; China; Databases, Factual; Urolithiasis/etiology",,"National Natural Science Foundation of China (82270797); National Natural Science Foundation of China (82270797); National Natural Science Foundation of China (82270797); Natural Science Foundation of Hubei Province, China (2022CFC020)",,http://dx.doi.org/10.1007/s00240-023-01447-1,37067622,10.1007/s00240-023-01447-1,,,0,004-486-715-614-224; 007-364-163-340-459; 007-415-173-311-675; 009-878-789-091-133; 011-334-271-948-389; 011-453-428-495-632; 019-516-916-484-007; 021-316-207-352-189; 026-022-450-623-442; 026-193-232-844-286; 027-041-544-181-358; 027-673-693-563-267; 029-952-509-616-627; 031-578-699-168-793; 034-848-326-501-297; 044-583-091-605-471; 047-767-312-098-561; 049-275-851-636-260; 052-674-602-315-972; 055-377-619-649-416; 055-830-574-796-377; 066-514-225-757-905; 066-649-662-484-069; 068-760-634-751-578; 074-637-771-751-009; 082-893-731-391-750; 083-143-670-584-076; 087-744-358-084-72X; 096-228-977-035-076; 106-593-100-499-575; 114-443-908-430-438; 151-334-434-256-675; 161-414-290-733-649; 167-373-519-239-682,11,false,, -000-667-231-896-402,VOSviewer and Bibliometrix.,2022-07-01,2022,journal article,Journal of the Medical Library Association : JMLA,15589439; 15365050,Medical Library Association,United States,Humberto Arruda; Edison Renato Silva; Marcus Lessa; Domício Proença; Roberto Bartholo,"VOSviewer (version 1.6.17, July 22, 2021). Centre for Science and Technology Studies, Leiden University, The Netherlands. https://www.vosviewer.com; free, donations accepted. Bibliometrix (version 3.1, Sep 24, 2021). Department of Economics and Statistics, University of Naples Federico II, Italy. info@bibliometrix.org; https://www.bibliometrix.org/; free, donations accepted.",110,3,392,395,Library science; Computer science,,Humans; Italy; Technology; Universities,,,https://jmla.pitt.edu/ojs/jmla/article/download/1434/2122 https://doi.org/10.5195/jmla.2022.1434,http://dx.doi.org/10.5195/jmla.2022.1434,36589296,10.5195/jmla.2022.1434,,PMC9782747,0,002-052-422-936-00X,358,true,cc-by,gold -000-712-467-171-627,"Financial technology and environmental, social and governance in sustainable finance: a bibliometric and thematic content analysis",2025-03-01,2025,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Jewel Kumar Roy; László Vasa,"Abstract; The integration of Environmental, Social, and Governance (ESG) principles with Financial Technology (Fintech) has emerged as a pivotal mechanism for advancing sustainable finance. This study investigates the interplay between ESG and Fintech through bibliometric and thematic content analysis to uncover key research trends, thematic clusters, and existing knowledge gaps in this dynamic field. The research problem focuses on how FinTech innovations can support ESG-driven initiatives such as corporate social responsibility (CSR), financial inclusion, and sustainable development while addressing challenges like performance metrics and governance issues. By mapping the research landscape, the study identifies significant contributions from scholars, notably in China and the USA, and explores prominent themes, including the role of Fintech in ESG disclosures, corporate governance, and sustainability. Emerging technologies like AI and blockchain are also highlighted for their impact on ESG reporting. The findings reveal exponential academic interest in this domain but underscore critical industrial challenges, such as the absence of standardized ESG metrics and the limited application of Fintech in addressing sustainability issues. The study concludes by offering future research directions aimed at bridging these gaps and emphasizing the transformative potential of Fintech in driving sustainability across the financial sector.",6,1,,,Corporate governance; Thematic map; Content analysis; Business; Finance; Thematic analysis; Sustainable development; Accounting; Political science; Sociology; Qualitative research; Social science; Geography; Cartography; Law,,,,Széchenyi István University,,http://dx.doi.org/10.1007/s43621-025-00934-2,,10.1007/s43621-025-00934-2,,,0,007-400-397-202-185; 007-804-724-061-756; 017-906-578-200-649; 018-086-487-709-971; 025-004-088-590-637; 026-281-780-721-594; 027-737-464-393-807; 032-686-658-000-93X; 036-326-465-327-959; 036-539-194-989-393; 037-322-468-587-797; 039-240-525-774-614; 045-340-959-312-48X; 046-640-385-467-634; 052-423-038-375-993; 054-087-156-369-108; 057-192-718-003-92X; 057-420-467-269-855; 058-680-151-296-053; 065-456-226-335-414; 069-251-273-502-728; 071-703-256-408-349; 084-654-328-089-169; 085-557-382-443-626; 086-428-833-166-88X; 094-594-780-190-088; 111-220-382-174-056; 111-691-226-595-562; 112-980-246-890-064; 115-205-698-216-494; 120-442-504-912-513; 128-992-413-139-681; 145-667-215-353-465; 146-118-037-463-390; 151-236-636-654-47X; 152-259-496-712-209; 157-824-816-926-021; 161-048-404-291-782; 170-021-970-633-296; 184-196-244-824-189; 197-932-908-772-014,1,true,cc-by,gold -000-848-264-004-813,Conceptual evolution of the bioeconomy: a bibliometric analysis.,2021-05-05,2021,journal article,"Environment, development and sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Benoît Mougenot; Jean Pierre Doussoulin,"The growing concern over the change in climatic conditions and the management and conservation of biological resources makes it necessary to create models suitable for the sustainable management of these resources. The bioeconomy suggests a model based on the production of renewable biological resources and the conversion of these resources into value-added products. The main aim of this article is to assess the impact of the bioeconomy on the scholar. This manuscript also aims to continue and update this discussion of public policies oriented toward a bioeconomy. This research follows a computed analysis based on the R package using Biblioshiny, a web interface for Bibliometrix analysis; this approach offers a positive alternative for studying bioeconomic literature in the traditional bibliometric analysis. This is one of the first research which analyzes the literature pathways of the bioeconomy issue using a computational analysis. Our article concludes that the principles of the bioeconomy have a strong potential to address these related challenges to manage and maintain the environment.",24,1,1,17,Public policy; Environmental economics; Business; Bioeconomics; Production (economics); Sustainable management; Bibliometric analysis; Ecology (disciplines); Sustainable development; User interface,Bibliometric analysis; Bioeconomics; Environment,,,,https://europepmc.org/article/MED/33967598 https://link.springer.com/article/10.1007/s10668-021-01481-2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096632 https://link.springer.com/content/pdf/10.1007/s10668-021-01481-2.pdf https://pubmed.ncbi.nlm.nih.gov/33967598/,http://dx.doi.org/10.1007/s10668-021-01481-2,33967598,10.1007/s10668-021-01481-2,3157497917,PMC8096632,0,001-270-436-059-49X; 001-946-071-544-253; 003-548-346-326-503; 010-428-406-921-521; 010-785-413-983-910; 012-645-422-200-349; 013-507-404-965-47X; 013-550-427-071-552; 013-681-353-103-709; 014-194-029-672-094; 014-729-280-951-50X; 016-131-059-057-660; 016-814-980-495-698; 020-154-692-215-085; 021-628-230-694-219; 025-315-261-166-53X; 028-037-650-718-395; 031-736-198-982-587; 032-236-755-528-607; 035-897-086-767-404; 040-483-013-803-84X; 043-131-760-368-351; 045-643-900-040-510; 048-153-363-208-003; 049-391-379-302-694; 050-631-422-293-099; 054-010-368-974-793; 063-616-596-789-04X; 066-664-293-660-201; 070-423-387-284-734; 076-890-496-849-344; 083-878-937-843-725; 085-306-160-040-77X; 090-071-921-773-95X; 094-570-718-690-130; 095-414-095-594-928; 098-129-801-227-241; 098-715-786-816-049; 104-846-547-029-000; 105-399-453-496-702; 108-638-093-371-811; 113-046-060-089-782; 116-908-076-815-692; 138-355-328-147-514; 142-509-183-021-323; 143-075-542-230-495; 147-037-737-663-520; 153-936-915-307-411; 160-463-524-471-472; 168-045-916-782-80X; 175-974-799-536-684,49,true,,green -000-860-059-559-627,Value-focused thinking na prática: análise do desenvolvimento e aplicações no período (2010-2018),,2019,conference proceedings article,Anais do Simpósio Brasileiro de Pesquisa Operacional,29651476,Galoa,,Rafael Françozo; Mischel Carmen Neyra Belderrain; Níssia Carvalho Rosa Bergiante; Bruna Cristine Scarduelli Pacheco; Claudio Luis Piratelli,"The Value Focused Thinking (VFT) has introduced by Keeney 1992 as important complex decision-making tool from decision makers values.Parnell et. al. (2013) performs the first literature review about VFT between 1992-2010.This study aims update this review to 2010-2018 period as well as show trends and main areas of research.For this purpose Web of Science, Scopus e Google Scholar bases were consulted and the results were analyzed by Bibliometrix and VosViewer softwares.As results, was identified the growth in the use of the VFT with 11 papers/year spread in 75 journals with predominantly applications in environment, energy efficiency, information technology, health, military, public and governmental.The results also indicate trends towards more geographic spread with papers from the USA, Brazil, Portugal, German and United Kingdom.",,,,,Value (mathematics); Computer science; Mathematics; Statistics,,,,,https://proceedings.science/proceedings/100090/_papers/106817/download/abstract_file2?lang=pt-br https://doi.org/10.59254/sbpo-2019-106817,http://dx.doi.org/10.59254/sbpo-2019-106817,,10.59254/sbpo-2019-106817,,,0,,1,true,,bronze -000-899-727-225-867,Preprocesamiento de publicaciones acerca de indentidad digital descentralizada y autgobernada.,2022-01-01,2022,dataset,Figshare,,,,Roberto Pava,Referencias en formato bibtex obtenidas de las bases de datos Scopus y WoS. Preprocesamiento con el paquete bibliometrix,,,,,Psychology; Philosophy,,,,,https://figshare.com/articles/dataset/Referencias_sobre_SSI_obtenidas_en_formato_bibtex/19579492/5,http://dx.doi.org/10.6084/m9.figshare.19579492.v5,,10.6084/m9.figshare.19579492.v5,,,0,,0,true,cc-by,gold -001-193-773-983-820,Contributions of the balanced scorecard as a support instrument in strategic decision-making: a bibliometric study,,2023,journal article,International Journal of Bibliometrics in Business and Management,20570538; 20570546,Inderscience Publishers,,Sidalina Maria d; os Santos Gonçalves; José Biléu Ventura; Orlando Lima Rua; Óscar Bernardes,"Despite the existence of various studies and literature reviews conducted around the balanced scorecard theme, it is considered important to undertake an in-depth update of the state of the art on this subject. To achieve this purpose, our research aims to conduct a bibliometric study to analyse the contributions of the balanced scorecard as an instrument to support strategic decision-making. To this end, we conducted a comprehensive state-of-the-art survey from an advanced search based on the Web of Science. 1,768 articles, published between 1992 and 2021, were considered for this purpose. The analysis is done using innovative software for bibliometric analysis - R. Bibliometrix. We note that most publications deal with the combination of the balanced scorecard with management systems such as the quality management system and the performance evaluation system and, more recently, with big data algorithms.",2,3,210,245,Balanced scorecard; Strategy map; Computer science; Performance measurement; Quality (philosophy); Management science; Process management; Knowledge management; Business; Engineering; Marketing; Philosophy; Epistemology,,,,,,http://dx.doi.org/10.1504/ijbbm.2023.134434,,10.1504/ijbbm.2023.134434,,,0,,1,false,, -001-655-118-733-677,An overview of research on natural resources and indigenous communities: a bibliometric analysis based on Scopus database (1979–2020),2021-01-13,2021,journal article,Environmental monitoring and assessment,15732959; 01676369,Springer Science and Business Media LLC,Netherlands,Manoranjan Mishra; Desul Sudarsan; Celso Augusto Guimarães Santos; Shailendra Kumar Mishra; Dipika Kar; Kabita Baral; Namita Pattnaik,,193,2,1,17,Cultural diversity; Social exclusion; Regional science; Qualitative research; Geography; Globalization; Natural resource; Industrialisation; Indigenous; Scopus,Bibliographic databases; Cocitation; Science mapping; Scientometrics; VOSviewer; Workflow,"Bibliometrics; Databases, Factual; Environmental Monitoring; Humans; Natural Resources; Population Groups",,Indian Council of Social Science Research (IMPRESS/P876/39/18-19),https://www.ncbi.nlm.nih.gov/pubmed/33442808 https://pubmed.ncbi.nlm.nih.gov/33442808/ https://pubag.nal.usda.gov/catalog/7235273 https://link.springer.com/article/10.1007/s10661-020-08793-2,http://dx.doi.org/10.1007/s10661-020-08793-2,33442808,10.1007/s10661-020-08793-2,3121099422,,0,002-052-422-936-00X; 004-819-527-814-707; 005-707-887-783-406; 006-335-717-676-108; 006-645-643-880-643; 009-833-006-214-362; 013-507-404-965-47X; 015-109-791-992-126; 016-738-848-740-009; 018-318-771-002-789; 021-856-043-273-333; 022-937-587-028-994; 023-927-221-065-800; 036-126-901-640-356; 039-315-623-079-272; 042-339-130-334-727; 047-134-478-431-993; 049-627-380-946-946; 054-818-565-070-154; 060-110-039-971-60X; 065-516-419-444-125; 065-545-309-411-827; 072-856-861-900-730; 082-228-143-877-463; 089-209-126-495-675; 093-775-790-777-612; 096-392-210-054-786; 102-631-500-719-273; 106-471-490-203-315; 106-831-281-915-70X; 107-518-655-388-824; 111-159-503-737-506; 112-970-251-640-570; 120-791-523-892-226; 124-814-014-669-995; 128-217-524-056-953; 138-561-175-358-392; 141-097-082-692-860; 146-495-957-439-143; 177-056-780-474-428,64,false,, -001-965-830-922-897,Energy Financing in Colombia: A Bibliometric Review,2022-03-20,2022,journal article,International Journal of Energy Economics and Policy,21464553,EconJournals,Turkey,William Niebles-Nunez; Leonardo Niebles-Nunez; Lorena Hoyos Babilonia,"This article presents a bibliometric review on the researching topic ""Contribution to the competitiveness of energy financing in the Colombian business sector"", limited from 2011 to 2021. The review was carried out using the Scopus database, obtaining a set of 76 studies in Colombia within the 2609 documents analyzed. After having applied the different filters and search strategies, these studies were analyzed using the Bibliometrix package of the statistical software R. The results identified, for example, that the world production of publications shows an upward trend, with the largest number of scientific investigations presented in 2020. It was also found that one of the most relevant sources is the International Journal of Energy Economics and politics, with five published documents. On the other hand, the most cited local source is Energy Policy magazine, with 90 citations and that the most cited local authors are Cadavid L.",12,2,459,466,Scopus; Database; Regional science; Library science; Political science; Economics; Computer science; Geography; MEDLINE; Law,,,,,,http://dx.doi.org/10.32479/ijeep.12819,,10.32479/ijeep.12819,,,0,,3,true,cc-by,gold -002-644-986-206-79X,A scientometric analysis of neuroblastoma research,2020-05-29,2020,journal article,BMC cancer,14712407,Springer Science and Business Media LLC,United Kingdom,Illya Martynov; Jessica Klima-Frysch; Joachim Schoenberger,"Thousands of research articles on neuroblastoma have been published over the past few decades; however, the heterogeneity and variable quality of scholarly data may challenge scientists or clinicians to survey all of the available information. Hence, holistic measurement and analyzation of neuroblastoma-related literature with the help of sophisticated mathematical tools could provide deep insights into global research performance and the collaborative architectonical structure within the neuroblastoma scientific community. In this scientometric study, we aim to determine the extent of the scientific output related to neuroblastoma research between 1980 and 2018. We applied novel scientometric tools, including Bibliometrix R package, biblioshiny, VOSviewer, and CiteSpace IV for comprehensive science mapping analysis of extensive bibliographic metadata, which was retrieved from the Web of ScienceTM Core Collection database. We demonstrate the enormous proliferation of neuroblastoma research during last the 38 years, including 12,435 documents published in 1828 academic journals by 36,908 authors from 86 different countries. These documents received a total of 316,017 citations with an average citation per document of 28.35 ± 7.7. We determine the proportion of highly cited and never cited papers, “occasional” and prolific authors and journals. Further, we show 12 (13.9%) of 86 countries were responsible for 80.4% of neuroblastoma-related research output. These findings are crucial for researchers, clinicians, journal editors, and others working in neuroblastoma research to understand the strengths and potential gaps in the current literature and to plan future investments in data collection and science policy. This first scientometric study of global neuroblastoma research performance provides valuable insight into the scientific landscape, co-authorship network architecture, international collaboration, and interaction within the neuroblastoma community.",20,1,1,10,Data collection; Political science; Data science; Citation; Science policy; R package; Science mapping; Scientometrics; Metadata,Children; Network analysis; Neuroblastoma; Research performance; Scientometrics,"Bibliometrics; Biomedical Research/statistics & numerical data; Child; Databases, Factual/statistics & numerical data; Humans; Metadata/statistics & numerical data; Neuroblastoma",,,https://portal.dnb.de/opac.htm?method=simpleSearch&cqlMode=true&query=idn%3D1214999638 https://pubmed.ncbi.nlm.nih.gov/32471384/ https://www.researchsquare.com/article/rs-11384/v2 https://www.scilit.net/article/8723a463b9b339e0762b36440bf89ab4 https://bmccancer.biomedcentral.com/articles/10.1186/s12885-020-06974-3/email/correspondent/c1/new https://www.researchsquare.com/article/rs-11384/v2.pdf?c=1631846721000 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260742 https://europepmc.org/article/MED/32471384 https://d-nb.info/1214999638/34 https://bmccancer.biomedcentral.com/articles/10.1186/s12885-020-06974-3 https://link.springer.com/article/10.1186/s12885-020-06974-3 https://link.springer.com/content/pdf/10.1186/s12885-020-06974-3.pdf,http://dx.doi.org/10.1186/s12885-020-06974-3,32471384,10.1186/s12885-020-06974-3,3030430768,PMC7260742,0,001-458-470-523-190; 002-052-422-936-00X; 003-892-507-044-455; 005-613-236-462-230; 010-874-514-352-944; 012-182-723-545-73X; 013-507-404-965-47X; 017-844-459-389-177; 019-273-741-784-804; 020-024-082-950-722; 020-535-777-774-555; 023-753-538-657-751; 024-736-628-389-289; 025-251-771-848-303; 030-024-244-082-167; 033-578-906-524-58X; 039-341-572-339-781; 040-556-667-707-237; 052-768-238-819-580; 057-341-881-026-730; 057-403-777-432-668; 059-115-199-056-133; 061-481-068-475-698; 063-462-721-383-315; 063-795-600-903-420; 063-895-503-274-528; 065-823-330-201-426; 074-169-520-421-190; 077-357-567-015-314; 082-165-313-175-021; 082-393-900-588-829; 085-709-887-797-761; 088-885-097-585-360; 098-085-037-210-177; 099-603-522-803-631; 101-752-490-869-458; 104-679-862-086-632; 111-736-787-572-957; 119-330-906-824-16X; 123-668-840-593-735; 137-562-013-924-29X; 138-413-997-981-429; 166-369-641-785-072,47,true,"CC BY, CC0",gold -002-673-627-099-702,A BIBLIOMETRIC ANALYSIS OF PUBLICATION ON PERFORMANCE MANAGEMENT IN PUBLIC INSTITUTIONS,,2024,journal article,European Journal of Public Administration Research,30084504,Editura Universitatii Alexandru Ioan Cuza din Iasi,,SILVIU MIHAIL TIŢĂ; CARMEN TIŢĂ,"This article researches the implications of performance management in public; institutions. The methodological approach is based on the use of the bibliometric; software R-Stata Bibliometrix, specialized in Science Mapping Workflow, to extract; meaningful results about the thematic evolution of the performance management in the; publication indexed by the Web of Science database. Our search is about “performance; management in public institution” and the bibliometric analysis unigram, bigram, and; thematic evolutions is about the title and abstract of the articles. The scope of the; research is to identify which are the new trends at publication in this field of; performance in public administration.",,2,49,58,Bibliometrics; Library science; Political science; Regional science; Computer science; Geography,,,,,,http://dx.doi.org/10.47743/ejpar.2023-2-5,,10.47743/ejpar.2023-2-5,,,0,,0,true,,bronze -002-775-484-077-617,Cultural differences in global virtual teams: mapping knowledge and identifying research directions,2023-07-26,2023,journal article,Journal of Management & Organization,18333672; 18393527,Cambridge University Press (CUP),United Kingdom,Mariya Kargina,"Abstract; This study examines research performance indicators and builds a structural overview of topics related to cultural differences in global virtual teams (GVT) in the period 2000-2020. A bibliometric analysis of 151 academic articles on the topic of cultural differences in GVTs, retrieved from Web of Science Core Collection and Scopus databases, was applied with the Bibliometrix package in R. The analyses reveal findings regarding the cultural differences in GVTs research, in particular, the most valuable sources, prolific authors, the geography of the research, as well as main scientific articles. The main research themes and their evolution were determined, as well as potential research directions. According to the revealed most relevant themes, the trend of the stream of research is heading towards individual dimensions of the topic, indicating a moved research focus from the organizational level of management and psychology to the individual one.",,,1,21,Scopus; Web of science; Bibliometrics; Knowledge management; Heading (navigation); Sociology; Data science; Library science; Computer science; Geography; Political science; MEDLINE; Geodesy; Law,,,,,,http://dx.doi.org/10.1017/jmo.2023.41,,10.1017/jmo.2023.41,,,0,002-088-819-048-54X; 002-289-788-966-348; 004-496-753-982-596; 006-301-433-281-440; 007-016-826-558-870; 007-190-100-445-758; 007-653-870-445-47X; 008-146-495-921-306; 011-670-571-711-335; 011-964-652-361-019; 013-418-408-450-575; 013-507-404-965-47X; 013-916-888-471-050; 016-490-524-014-258; 016-953-370-692-74X; 017-310-909-673-962; 018-418-169-586-222; 019-397-878-251-819; 021-362-523-245-286; 021-775-005-542-657; 023-011-148-884-155; 025-302-119-966-613; 025-576-072-224-249; 029-630-105-600-854; 030-288-965-597-653; 032-704-019-084-598; 033-574-461-303-339; 040-637-811-266-793; 043-844-461-618-357; 045-830-723-373-958; 046-669-794-380-037; 047-073-827-575-164; 047-134-478-431-993; 048-109-011-676-032; 053-850-052-433-822; 054-500-966-915-656; 055-273-552-334-543; 058-974-638-090-392; 060-547-151-741-291; 062-952-811-445-992; 064-352-693-479-73X; 065-636-942-733-657; 067-509-080-881-840; 067-950-923-597-803; 070-190-681-537-486; 070-708-457-505-15X; 079-346-702-065-058; 079-669-675-228-769; 080-021-841-920-130; 084-249-962-919-116; 084-872-474-062-779; 085-159-530-193-996; 085-579-536-264-354; 086-078-664-709-646; 087-860-235-413-616; 091-054-197-492-146; 091-209-012-459-475; 095-710-082-486-414; 098-648-038-105-666; 099-045-864-033-485; 100-265-653-679-305; 101-675-601-402-089; 101-770-960-335-274; 110-850-423-868-020; 111-125-610-322-757; 114-221-761-175-415; 118-606-418-909-533; 120-975-417-040-341; 121-958-932-471-148; 123-202-581-406-928; 123-949-004-938-313; 125-505-607-586-72X; 125-638-291-011-151; 125-757-289-700-259; 126-445-326-104-389; 130-667-504-614-76X; 133-596-178-675-658; 140-512-558-906-684; 142-560-824-569-481; 146-492-353-052-999; 152-844-486-370-812; 160-369-062-975-498; 162-682-341-086-830; 165-930-545-615-465; 175-421-742-112-75X; 189-563-619-366-887,2,false,, -003-078-760-554-604,Uma análise da produção científica em altmetria na Scopus Indicadores de Produtividade e Comunicação na Web Social,,2024,conference proceedings article,Anais do 9º Encontro Brasileiro de Bibliometria e Cientometria - EBBC,,Instituto Brasileiro de Informação em Ciência e Tecnologia,,Maurício Coelho da Silva; Lucas George Wendt; Ana Maria Mielniczuk de Moura; Francielle Franco dos Santos,"O estudo teve como objetivo geral analisar a produção científica em altmetria indexada na Scopus a partir dos indicadores de produtividade e comunicação na web social. Sua metodologia inclui procedimentos bibliométricos, altmétricos e o uso do software Bibliometrix para processamento dos dados coletados. Os resultados descrevem uma perda de impacto da Altmetria em relação à medida de citação. São apontados os autores mais produtivos e periódicos nucleares na temática, bem como suas políticas de Acesso Aberto. São discutidas também relações entre indicadores bibliométricos e altmétricos.",,,,,Scopus; Computer science; Physics; Chemistry; MEDLINE; Biochemistry,,,,,,http://dx.doi.org/10.22477/ix.ebbc.337,,10.22477/ix.ebbc.337,,,0,,0,false,, -003-086-731-715-798,An overview of probabilistic preference decision-making based on bibliometric analysis,2022-03-15,2022,journal article,Applied Intelligence,0924669x; 15737497,Springer Science and Business Media LLC,Netherlands,Zeshui Xu; Tiantian Lei; Yong Qin,,52,13,15368,15386,Computer science; Probabilistic logic; Citation; Theme (computing); General partnership; Preference; Management science; Operations research; Data science; Artificial intelligence; World Wide Web; Engineering; Economics; Microeconomics; Finance,,,,national natural science foundation of china,,http://dx.doi.org/10.1007/s10489-022-03189-w,,10.1007/s10489-022-03189-w,,,0,002-052-422-936-00X; 002-793-753-889-373; 009-286-240-384-618; 013-425-159-910-299; 013-507-404-965-47X; 017-146-468-093-265; 021-871-915-969-625; 024-516-003-611-383; 035-742-245-934-729; 039-619-786-028-157; 039-818-465-235-94X; 039-830-607-260-297; 042-921-172-497-819; 044-021-769-025-899; 044-558-398-320-126; 044-886-160-748-803; 047-381-298-575-664; 052-476-372-291-436; 055-733-397-040-194; 056-426-226-149-95X; 060-110-039-971-60X; 064-400-499-357-900; 071-958-550-139-56X; 073-351-117-300-051; 079-050-236-131-309; 080-323-794-092-523; 080-735-974-338-157; 082-857-314-363-160; 084-848-720-663-685; 085-541-732-518-40X; 085-972-789-780-569; 089-409-767-761-917; 093-513-512-412-760; 094-023-744-239-340; 097-843-920-246-535; 100-372-791-378-192; 109-970-801-809-791; 112-491-920-263-138; 122-415-544-444-960; 137-891-002-130-90X; 144-287-319-787-11X; 145-286-017-239-259; 185-421-860-898-573,9,false,, -003-196-077-841-729,Global research trends on aquaponics: a systematic review based on computational mapping,2022-12-01,2022,journal article,Aquaculture International,09676120; 1573143x,Springer Science and Business Media LLC,Netherlands,Bwsrang Basumatary; A. K. Verma; Manoj Kumar Verma,,31,2,1115,1141,Aquaponics; Social media; Scopus; Aquaculture; Hydroponics; Environmental science; Computer science; Fish ; Fishery; World Wide Web; Political science; Biology; Agronomy; MEDLINE; Law,,,,,,http://dx.doi.org/10.1007/s10499-022-01018-y,,10.1007/s10499-022-01018-y,,,0,001-578-815-562-029; 002-479-544-742-556; 002-509-429-948-625; 004-286-649-679-428; 011-364-541-838-073; 013-507-404-965-47X; 013-848-964-561-065; 015-309-486-299-516; 015-343-373-343-620; 017-188-058-847-074; 017-281-633-948-899; 020-625-321-792-279; 024-684-727-608-692; 026-277-757-182-201; 029-420-167-353-195; 033-064-467-856-284; 033-765-573-033-865; 037-657-463-758-424; 039-739-083-330-014; 046-992-864-415-70X; 050-514-589-695-724; 053-537-726-139-013; 054-818-565-070-154; 061-130-871-104-891; 067-409-082-117-012; 075-553-686-296-580; 079-155-337-672-56X; 092-684-635-776-900; 093-186-636-893-601; 100-301-577-888-206; 101-752-490-869-458; 111-980-465-375-648; 112-533-001-418-656; 123-978-639-694-976; 137-769-898-882-661; 139-479-378-488-537; 141-902-329-730-312; 148-855-114-222-084; 177-946-841-414-774,25,false,, -003-262-652-053-888,Smart libraries: Unveiling research trends and knowledge dynamics through scientometrics,2025-02-08,2025,journal article,Journal of Librarianship and Information Science,09610006; 17416477,SAGE Publications,United States,Ufaira Yaseen; Sumeer Gul," Smart libraries, integrating advanced digital technologies to enhance information retrieval and user experience, have seen a dynamic research growth from 1990 to 2023. This study investigates the global research landscape of smart libraries, analyzing 1801 articles from 92 journals using scientometric techniques with Bibliometrix and MS-Excel. Findings indicate a 12.2% annual publication growth rate, with significant contributions from the USA, UK, and China, and highlight the prevalence of collaborative research. Prominent figures such as Professor Edward A. Fox and institutions like the University of California System are identified as key contributors. Thematic analyses underscore the importance of concepts like “digital libraries,” “information retrieval,” and “user studies” in shaping the field. The study provides practical insights for researchers, policymakers, and practitioners, identifying leading journals and institutions, and offering strategic directions for technological adoption and interdisciplinary collaboration in smart library initiatives. ",,,,,Scientometrics; Dynamics (music); Computer science; Data science; Knowledge management; Library science; Sociology; Pedagogy,,,,,,http://dx.doi.org/10.1177/09610006251316594,,10.1177/09610006251316594,,,0,001-436-421-380-691; 013-507-404-965-47X; 021-049-463-051-998; 028-168-258-398-761; 033-076-881-913-385; 040-217-749-473-335; 040-704-370-781-171; 051-978-374-039-238; 052-965-279-175-518; 052-979-464-645-267; 054-159-894-171-769; 054-855-039-028-872; 060-043-385-932-42X; 062-844-639-504-680; 063-325-944-586-901; 066-071-737-230-103; 086-802-948-468-981; 097-097-972-891-817; 101-418-000-229-842; 104-680-237-098-193; 113-672-094-172-208; 114-495-252-879-121; 116-107-598-411-695; 135-325-285-192-625; 142-015-130-366-862; 164-914-609-416-363; 176-106-397-745-148,1,false,, -003-513-536-309-448,Supplementary Material,2023-01-01,2023,dataset,Figshare,,,,null sheng,1. The total of 4856 articles Bibliometrix Export File 2.The most valuable articles Historiograph Network,,,,,Computer science,,,,,https://figshare.com/articles/dataset/Supplementary_Material/22262971,http://dx.doi.org/10.6084/m9.figshare.22262971,,10.6084/m9.figshare.22262971,,,0,,0,true,cc-by,gold -003-562-362-629-054,Visualization of scientific production in Caenorhabditis elegans: a bibliometric analysis (1980-2023).,2024-05-31,2024,journal article,Genomics & informatics,1598866x; 22340742,Springer Science and Business Media LLC,England,Şeyda Berk; Serkan Özdemir; Ayşe Nur Pektaş,"Caenorhabditis elegans (C. elegans) is a nematode and model organism whose entire genome has been mapped, which allows for easy observation of the organism's development due to its transparent structure, and which is appealing due to its ease of crossover, ease of culture, and low cost. Despite being separated by nearly a billion years of evolution, C. elegans homologs have been identified for the vast majority of human genes and are associated with C. elegans for many biological processes such as apoptosis, cell signaling, cell cycle, cell polarity, metabolism, and aging. A detailed bibliometric study is performed here to examine publication trends in this field. Data were taken from the Web of Science database and analyzed using the bibliometric application Biblioshiny (RStudio). In terms of publication, the results indicated a gradual increase each year between 1980 and 2023. A total of 20,322 records were issued in 96 countries, the majority of which were in the USA, China, and Japan. The most prolific writers, the journals most engaged in the area, the nations, institutions, and keywords used by authors were all determined using the Web of Science database and bibliometric rules. The number of papers in the C. elegans research field is increasing exponentially, and Genetics is the journal with the highest number of articles. This study presents how research patterns have evolved throughout time. As a result, worldwide cooperation and a potential field can be developed.",22,1,3,,Caenorhabditis elegans; Web of science; Biology; Organism; Field (mathematics); Model organism; Computational biology; Data science; Computer science; Gene; Genetics; MEDLINE; Biochemistry; Mathematics; Pure mathematics,"C. elegans - ; Bibliometric; Biblioshiny; Nematode; Web of Science",,,,https://genomicsinform.biomedcentral.com/counter/pdf/10.1186/s44342-024-00002-7 https://doi.org/10.1186/s44342-024-00002-7,http://dx.doi.org/10.1186/s44342-024-00002-7,38907345,10.1186/s44342-024-00002-7,,PMC11184956,0,002-688-191-558-77X; 004-254-332-806-998; 004-632-405-736-456; 004-775-031-174-951; 006-128-543-521-322; 006-286-417-909-610; 007-072-850-521-126; 007-517-733-496-75X; 012-593-634-707-369; 013-507-404-965-47X; 013-683-191-846-68X; 016-591-828-052-256; 018-020-177-526-297; 020-426-283-662-315; 026-720-367-266-622; 030-531-549-622-116; 034-531-705-346-738; 034-737-414-844-909; 034-768-039-318-254; 038-169-919-806-855; 042-012-217-885-148; 046-656-697-871-456; 049-847-302-095-124; 052-924-038-364-974; 054-488-628-634-094; 056-597-182-129-047; 059-192-677-212-057; 070-791-835-923-368; 101-740-533-637-30X; 103-842-565-214-985; 104-833-613-718-937; 106-941-451-733-392; 111-560-842-068-993; 119-944-136-958-44X; 120-974-286-046-262; 128-253-172-375-720; 130-405-170-556-298; 136-395-724-271-836; 146-208-436-691-12X; 167-003-134-808-479,2,true,cc-by,gold -003-566-188-442-865,"Mapping the Foundation -and Trends in Tourism Research",2022-06-14,2022,journal article,Tourism,18491545; 13327461,Institute for Tourism,Croatia,Asma Bashir; Ranjit Singh; Sibi PS,"Tourism: An International Interdisciplinary Journal is the second oldest journal in tourism, which has grown as one of the most reliable sources of tourism scholarship over the years. This study has adopted a bibliometric literature review approach based on the published articles to emphasize its contribution to tourism scholarship. The study has reviewed 529 publications published between 2002 and 2020 (indexed in Scopus). The study has employed the statistical tool - 'bibliometrix' to conduct evaluative and relational analysis utilizing numerous indices highlighting the journal's growth and its conceptual and collaboration structure. The findings offered are beneficial for both the editors and the scholars in the tourism discipline. Additionally, the implications of the findings, future research gaps, and limitations are discussed.",70,3,480,492,Scholarship; Scopus; Tourism; Foundation (evidence); Regional science; Sociology; Social science; Library science; Political science; Geography; Computer science; MEDLINE; Archaeology; Law,,,,,https://hrcak.srce.hr/file/404252 https://doi.org/10.37741/t.70.3.10,http://dx.doi.org/10.37741/t.70.3.10,,10.37741/t.70.3.10,,,0,,4,true,,gold -004-014-222-032-802,Cómo descargar datos de WOS para usar en R-bibliometrix,2020-05-20,2020,,,,,,Marín García; Juan Antonio,,,,,,,,,,,https://riunet.upv.es/handle/10251/143813,https://riunet.upv.es/handle/10251/143813,,,3042853612,,0,,0,false,, -004-341-505-045-652,"THE THIRD MISSION OF UNIVERSITIES TOWARDS KNOWLEDGE TRANSFER, INNOVATION, ENTREPRENEURSHIP, AND SUSTAINABLE DEVELOPMENT: A SYSTEMATIC LITERATURE REVIEW",,2025,journal article,Revista de Administração de Empresas,2178938x; 00347590,FapUNIFESP (SciELO),Brazil,Alix Johana Gaffaro Garcia; Yenny Naranjo Tuesta,"ABSTRACT The concept of the third mission of universities emphasizes the importance of universities actively collaborating with industry and society to promote knowledge transfer, innovation, and regional development. This article presents a systematic literature review conducted in the Scopus database, analyzing 67 papers to trace the evolution of research on this topic. Using tools such as VOSviewer and Bibliometrix for data visualization, a growing interest in areas such as the triple helix, technology transfer, and entrepreneurial universities was identified, while new areas of focus, including information management and the knowledge economy, are emerging. The methodology employed combines PRISMA method standards, bibliometric analysis, and systematic review. The results underscore the need to integrate the third mission into university strategies globally to advance sustainable development.",65,3,,,Entrepreneurship; Knowledge transfer; Knowledge management; Technology transfer; Sustainable development; Business; Engineering ethics; Political science; Engineering; Computer science; Finance; Law,,,,,,http://dx.doi.org/10.1590/s0034-759020250301x,,10.1590/s0034-759020250301x,,,0,002-052-422-936-00X; 002-345-146-777-848; 002-404-990-433-992; 003-734-795-535-609; 005-811-196-923-684; 005-831-362-546-975; 012-855-884-210-264; 013-507-404-965-47X; 017-300-737-144-757; 017-918-213-484-106; 038-749-605-325-320; 054-861-795-091-886; 057-549-995-320-99X; 063-647-018-033-525; 064-396-695-441-342; 073-838-075-391-85X; 077-385-560-263-225; 118-207-915-872-307; 120-094-718-338-889; 129-311-354-818-86X; 130-249-520-334-74X; 130-602-202-936-694; 150-803-217-054-893,0,true,cc-by-nc,gold -004-470-552-654-769,"What Country, University, or Research Institute, Performed the Best on Covid-19 During the First Wave of the Pandemic?: Bibliometric analysis of scientific literature - analysing a 'snapshot in time' of the first wave of COVID-19.",2022-06-28,2022,journal article,Annals of data science,21985812; 21985804,Springer Science and Business Media LLC,Germany,Petar Radanliev; David De Roure; Rob Walton; Max Van Kleek; Omar Santos; La'Treall Maddox,"In this article, we conduct data mining and statistical analysis on the most effective countries, universities, and companies, based on their output (e.g., produced or collaborated) on COVID-19 during the first wave of the pandemic. Hence, the focus of this article is on the first wave of the pandemic. While in later stages of the pandemic, US and UK performed best in terms of vaccine production, the focus in this article is on the initial few months of the pandemic. The article presents findings from our analysing of all available records on COVID-19 from the Web of Science Core Collection. The results are compared with all available data records on pandemics and epidemics from 1900 to 2020. This has created interesting findings that are presented in the article with visualisation tools.; The online version contains supplementary material available at 10.1007/s40745-022-00406-8.; © The Author(s) 2022.",9,5,1049,1067,Pandemic; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Political science; Medicine; Internal medicine; Outbreak; Infectious disease (medical specialty); Disease,Big data analytics; COVID-19; Computation; Data mining; Disease; Epidemic; Pandemic; Statistics; Virus,,,Engineering and Physical Sciences Research Council; Cisco Systems,https://link.springer.com/content/pdf/10.1007/s40745-022-00406-8.pdf https://doi.org/10.1007/s40745-022-00406-8,http://dx.doi.org/10.1007/s40745-022-00406-8,38625278,10.1007/s40745-022-00406-8,,PMC9243965,0,002-052-422-936-00X; 005-067-817-442-478; 013-507-404-965-47X; 016-131-059-057-660; 026-466-816-212-136; 031-272-185-806-899; 033-774-000-117-345; 043-615-813-272-224; 055-749-872-948-852; 056-405-254-662-635; 067-263-492-957-015; 093-361-737-817-232; 109-512-644-843-372; 160-360-469-166-106,9,true,cc-by,hybrid -004-660-857-829-336,"The growth of scientific publications in 2020: a bibliometric analysis based on the number of publications, keywords, and citations in orthopaedic surgery.",2021-08-01,2021,journal article,International orthopaedics,14325195; 03412695,Springer Science and Business Media LLC,Germany,Jing Sun; Andreas F. Mavrogenis; Marius M. Scarlat,,45,8,1905,1910,Bibliometrics; MEDLINE; Orthopedic Procedures; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Bibliometric analysis; General surgery; Orthopedic surgery; Medicine,,Bibliometrics; Humans; Orthopedic Procedures; Orthopedics; Publications,,,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325773 https://link.springer.com/content/pdf/10.1007/s00264-021-05171-6.pdf https://pubmed.ncbi.nlm.nih.gov/34333676/ https://link.springer.com/article/10.1007/s00264-021-05171-6 https://dx.doi.org/10.1007/s00264-021-05171-6,http://dx.doi.org/10.1007/s00264-021-05171-6,34333676,10.1007/s00264-021-05171-6,3189234139,PMC8325773,0,010-879-178-958-324; 016-114-170-016-459; 044-390-228-760-325; 053-254-827-881-196; 060-171-483-556-153; 064-264-695-662-36X; 132-870-927-712-296,17,true,,green -004-908-053-893-064,"Research hotspots, emerging patterns, and intellectual structure of homestay tourism: a bibliometric analysis",2023-10-18,2023,journal article,Quality & Quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Nagihan Cakmakoglu Arici; Dilara Eylul Koc,,58,3,2571,2589,Tourism; Excellence; Marketing; Bibliometrics; Empowerment; Political science; Business; Economic growth; Library science; Economics; Computer science; Law,,,,,,http://dx.doi.org/10.1007/s11135-023-01763-z,,10.1007/s11135-023-01763-z,,,0,000-459-327-210-35X; 002-796-750-754-24X; 004-288-964-025-116; 006-892-147-984-206; 007-104-213-010-730; 008-592-704-723-606; 008-887-584-746-51X; 009-696-724-387-817; 010-303-666-559-515; 010-857-192-135-415; 011-149-392-345-168; 011-472-657-686-655; 012-707-160-365-629; 013-507-404-965-47X; 013-541-969-076-695; 015-999-003-054-612; 016-698-743-791-797; 020-817-254-555-287; 021-312-058-132-060; 023-466-076-577-068; 027-744-035-592-248; 029-826-743-034-222; 030-944-397-099-332; 032-242-675-011-967; 032-319-788-541-06X; 033-519-356-101-047; 034-540-678-119-867; 036-533-827-630-923; 038-707-903-786-795; 038-890-751-304-141; 039-708-901-873-167; 043-519-014-613-512; 044-397-774-333-381; 050-067-090-092-076; 053-791-490-990-592; 059-093-642-477-983; 064-056-604-862-205; 065-979-547-115-28X; 066-849-661-222-258; 070-368-736-425-074; 073-168-622-355-47X; 075-198-915-460-185; 077-063-362-574-135; 077-725-452-074-433; 079-070-675-840-033; 084-512-012-896-518; 092-401-602-322-192; 095-163-212-281-637; 103-883-135-825-840; 104-618-500-777-242; 109-144-284-602-404; 114-895-323-255-977; 128-198-705-494-484; 129-525-784-832-577; 132-951-365-390-620; 133-165-318-273-139; 133-190-995-147-951; 151-587-050-709-896; 155-882-469-293-655; 162-750-563-310-465; 163-058-194-334-271; 166-347-904-377-381; 167-447-915-008-316; 171-767-779-157-735; 178-935-941-875-300; 186-842-017-005-091; 198-005-872-834-12X,3,false,, -004-965-185-191-196,Understanding the application of digital technologies in aquaculture supply chains through a systematic literature review,2025-06-14,2025,journal article,Aquaculture International,09676120; 1573143x,Springer Science and Business Media LLC,Netherlands,Iyabo Toyin Adebayo; Segun Ajibola; Ali Ahmad; Pedro Cartujo; Ibrahim Muritala; Isa O. Elegbede; Pedro Cabral; Vanessa Martos,"Abstract; The study conducts a systematic literature review of the application of digital technologies in aquaculture supply chains (ASC) to identify key research clusters, examine collaborative efforts in the field, and highlight emerging knowledge themes. The methodology comprises a database search in Scopus and Web of Science over a 5-year period (2019–2023) following the PRISMA framework. Bibliometric analysis using Biblioshiny reveals that “Climate Change,” “Aquaculture”, “Sustainability”, and “Food Security” were dominant keywords in this field. Notably, the Sustainability cluster exhibits the highest Callon Centrality (2.819) and Callon Density (63.378), underscoring significant research focus on integrating digital technologies to enhance sustainability in ASC. Hungary emerges as the country with the strongest international research collaboration. However, we identified weak collaboration between African nations and the global research community. Five primary research themes were identified; these include the role of digital technologies in ASC optimization, the disruption of fisheries supply chains due to the COVID-19 pandemic and the mitigating role of digital innovations, the contribution of digital technologies to reducing food waste and advancing the circular economy, the impact of climate change on fishes, and the challenges and opportunities in applying digital solutions within ASC. Despite persistent challenges—such as limited transmission bandwidth, network delays, and issues with low-power, long-range communication—significant opportunities exist to overcome these barriers through technological advances and stronger global research collaboration. Such progress is vital to transforming ASC into a more sustainable and competitive system. The study provides actionable insights for stakeholders while laying a foundation for future research and governance in this evolving field.",33,6,,,,,,,"This research was funded by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie-RISE, Project SUSTAINABLE; This research was funded by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie-RISE, Project SUSTAINABLE; This research was funded by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie-RISE, Project SUSTAINABLE; This research was funded by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie-RISE, Project SUSTAINABLE; This research was funded by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie-RISE, Project SUSTAINABLE; This research was funded by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie-RISE, Project SUSTAINABLE; This research was funded by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie-RISE, Project SUSTAINABLE; This research was funded by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie-RISE, Project SUSTAINABLE",,http://dx.doi.org/10.1007/s10499-025-02069-7,,10.1007/s10499-025-02069-7,,,0,000-560-446-039-600; 000-715-008-865-48X; 000-944-106-140-211; 001-520-709-349-740; 002-216-946-860-593; 002-233-000-145-702; 004-488-501-273-822; 004-747-448-350-764; 004-946-852-390-145; 005-749-966-505-936; 006-647-749-793-547; 007-915-241-048-110; 009-012-095-853-212; 010-065-762-504-134; 010-169-784-976-040; 010-236-953-800-634; 011-154-880-456-496; 011-734-465-657-312; 012-162-081-192-515; 012-680-580-866-65X; 013-069-402-621-369; 013-276-982-856-00X; 013-507-404-965-47X; 013-524-854-219-241; 014-851-409-449-537; 015-276-436-539-843; 016-129-086-285-420; 016-297-620-175-946; 017-493-400-684-065; 017-815-755-381-791; 019-155-911-415-562; 019-375-144-602-344; 019-628-941-421-59X; 020-763-110-326-265; 020-873-451-164-249; 021-700-571-174-32X; 021-883-274-138-693; 022-798-680-708-268; 022-938-954-965-301; 025-996-360-662-738; 026-676-487-277-769; 027-396-885-561-116; 028-722-016-401-310; 029-145-279-510-681; 029-410-858-845-616; 030-399-351-065-806; 030-487-134-502-790; 033-398-764-802-24X; 034-064-344-824-844; 034-383-530-112-291; 034-609-953-431-912; 035-431-036-005-052; 035-471-126-123-366; 036-562-650-449-098; 037-979-684-071-900; 039-241-853-249-637; 040-390-812-155-313; 040-891-119-828-853; 042-992-468-624-141; 047-521-835-869-783; 049-118-317-426-301; 049-227-004-333-30X; 052-349-425-969-668; 053-809-996-706-563; 055-698-971-508-02X; 056-406-541-298-666; 057-056-193-918-919; 057-689-900-382-237; 057-803-697-074-453; 058-194-311-214-085; 058-318-026-918-157; 058-701-862-881-523; 059-244-797-841-247; 059-356-429-761-258; 060-345-816-569-76X; 060-736-669-717-459; 061-413-041-696-47X; 064-883-198-193-905; 065-010-405-236-060; 067-486-050-850-315; 070-791-835-923-368; 071-111-895-304-600; 073-645-884-929-014; 075-448-099-632-995; 076-228-165-345-057; 077-131-873-430-442; 079-604-164-254-167; 081-145-555-825-934; 083-532-752-493-548; 083-615-462-726-458; 085-282-103-760-822; 089-440-933-270-378; 091-403-717-686-714; 091-489-925-216-135; 091-609-282-143-238; 093-938-913-129-644; 094-203-324-494-984; 094-281-743-448-118; 095-082-915-517-015; 095-538-132-825-575; 097-359-138-600-704; 099-478-698-777-879; 100-223-457-713-144; 102-540-366-919-333; 103-788-776-014-591; 104-149-204-689-206; 105-682-881-321-46X; 107-935-970-761-980; 109-197-870-716-956; 111-469-352-362-690; 111-752-629-244-843; 112-629-787-130-22X; 113-124-692-247-567; 114-192-753-128-969; 115-239-358-614-678; 117-543-784-037-999; 120-535-509-138-11X; 121-832-891-724-490; 123-252-777-467-971; 125-108-187-266-690; 129-965-279-196-230; 130-119-224-702-83X; 131-116-830-987-508; 132-486-305-609-968; 134-985-477-712-653; 135-457-702-864-168; 136-471-613-285-25X; 137-879-140-374-02X; 137-915-893-369-554; 138-219-213-670-747; 144-760-543-572-181; 144-791-157-291-99X; 147-199-278-864-535; 148-089-014-742-699; 148-697-147-142-733; 150-983-304-273-489; 152-829-111-993-903; 153-616-741-948-258; 155-407-272-307-336; 157-302-719-107-560; 159-889-688-283-569; 162-685-276-514-707; 163-747-476-683-289; 164-206-453-050-07X; 166-783-617-875-194; 171-461-827-964-143; 171-674-257-473-746; 174-910-943-344-400; 177-349-821-523-433; 181-934-118-730-643; 182-039-645-661-964; 183-450-994-406-802; 183-510-015-599-906; 185-560-582-916-873; 186-595-489-178-948; 196-740-718-691-261; 198-465-788-090-188; 199-105-079-586-006,0,true,cc-by,hybrid -005-220-762-250-505,A bibliometric analysis of green technologies applied to water and wastewater treatment.,2022-01-29,2022,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Naghmeh Niknejad; Behzad Nazari; Saman Foroutani; Ab Razak Bin Che Hussin,,30,28,71849,71863,Reuse; Wastewater; Water scarcity; Wetland; Sewage treatment; Desalination; Environmental science; Environmental economics; Water quality; Emerging technologies; Environmental planning; Environmental resource management; Water resources; Environmental engineering; Computer science; Engineering; Waste management; Ecology; Economics; Genetics; Artificial intelligence; Membrane; Biology,Bibliometrix R Package; Green technologies; VOSviewer; Wastewater treatment; Water treatment,Humans; Water Purification/methods; Water Supply; Conservation of Natural Resources/methods; Fresh Water; Technology,,Universiti Teknologi Malaysia,,http://dx.doi.org/10.1007/s11356-022-18705-1,35091956,10.1007/s11356-022-18705-1,,,0,000-468-721-330-602; 001-933-038-689-247; 002-052-422-936-00X; 002-808-120-653-271; 002-906-177-183-548; 005-447-483-426-041; 005-581-947-187-390; 006-666-415-331-477; 006-746-815-222-253; 009-308-034-589-983; 010-985-678-352-520; 012-316-085-232-181; 013-507-404-965-47X; 023-471-372-885-491; 024-431-351-675-25X; 024-711-982-386-979; 025-846-596-580-073; 025-938-643-576-252; 026-404-912-280-813; 028-110-859-227-085; 028-418-370-507-824; 030-278-274-711-606; 031-622-652-489-712; 032-517-972-801-148; 033-189-757-772-619; 033-712-329-072-169; 035-926-930-950-774; 037-824-780-268-459; 039-662-853-775-317; 041-353-516-626-399; 042-193-048-452-418; 046-188-312-137-177; 046-457-845-994-617; 049-117-936-194-963; 050-470-108-585-750; 054-818-565-070-154; 055-558-663-928-87X; 060-206-701-399-748; 060-918-627-605-966; 062-973-749-309-190; 068-330-175-821-812; 072-418-079-801-476; 074-248-989-581-891; 074-460-858-526-33X; 074-804-715-683-131; 075-966-045-815-606; 078-298-965-556-393; 079-149-682-224-10X; 080-038-872-330-193; 084-720-254-224-147; 085-195-340-541-855; 086-336-930-934-74X; 089-328-108-238-917; 097-759-335-124-834; 100-461-164-361-29X; 101-302-671-100-949; 102-299-568-692-116; 102-526-588-043-954; 103-145-942-688-681; 104-695-678-248-611; 110-397-708-101-007; 111-223-227-411-641; 114-416-712-470-805; 118-731-421-699-437; 119-612-544-958-341; 125-100-259-709-483; 128-137-634-101-137; 135-002-607-442-177; 141-490-182-312-387; 141-625-096-824-701; 146-379-683-424-164; 148-139-343-889-889; 149-942-709-162-22X; 155-383-662-253-19X; 178-274-779-008-886; 182-357-824-917-236,27,false,, -005-338-693-723-922,Bibliometrix: Science Mapping Analysis with R Biblioshiny Based on Web of Science in Applied Linguistics,2024-02-08,2024,book chapter,A Scientometrics Research Perspective in Applied Linguistics,,Springer Nature Switzerland,,Babak Daneshvar Ghorbani,"Bibliometric analysis has established itself as one of the leading approaches to visualizing a comprehensive picture of literature review across different disciplines over the past decade. As detailed in the paper, the researcher aimed to describe an open-source application that uses the R programming language to integrate a web-based interface into Biblioshiny, which performs a comprehensive analysis of the science mapping data. Bibliometrix supports a suggested methodology for conducting bibliometric analyses that can be used to conduct the analyses. This paper uses bibliometric analysis tools to visualize the relationship between published articles in the English language and technology-related publications (CALL, MALL, RALL) from 2013 to 2022. Additionally, the study followed the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. In accordance with PRISMA, 881 documents were analyzed using Bibliometrix from the WoS database. Ideally, to provide a comprehensive and systematic overview of research, two major levels of bibliometric analysis were selected, the intellectual structure and the conceptual structure, to illustrate a general and systematic overview. As a consequence, there is the possibility of gaining insight into the progress of research on specific topics, such as the most influential sources, authors, affiliations, countries, documents, and the scientific network among different constituencies as well as the evolution of research trends in the field. Hopefully, the insights provided in this paper will be useful to researchers from different disciplines who are interested in publishing authentic bibliometric studies.",,,197,234,Linguistics; Computer science; Sociology; Philosophy,,,,,,http://dx.doi.org/10.1007/978-3-031-51726-6_8,,10.1007/978-3-031-51726-6_8,,,0,002-052-422-936-00X; 009-286-240-384-618; 013-507-404-965-47X; 017-300-737-144-757; 017-750-600-412-958; 023-927-221-065-800; 045-797-416-772-535; 046-457-900-689-069; 054-818-565-070-154; 057-803-697-074-453; 060-110-039-971-60X; 073-367-985-641-83X; 083-311-225-108-952; 088-223-689-434-547; 098-377-939-800-955; 121-652-742-486-910; 123-202-581-406-928; 134-852-298-932-483; 147-199-278-864-535; 147-884-133-768-02X,18,false,, -005-519-023-109-993,Research trends and hotspots of aquatic biofilms in freshwater environment during the last three decades: a critical review and bibliometric analysis.,2022-05-06,2022,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Zhirui Qin; Zhenhua Zhao; Liling Xia; Okugbe Ebiotubo Ohore,,29,32,47915,47930,Web of science; Environmental research; Aquatic ecosystem; Biogeochemical cycle; Geography; Environmental planning; Ecology; Environmental science; Biology; MEDLINE; Biochemistry,Bibliometric analysis; Freshwater periphytic biofilms; Influential analysis; Publication trends; Research hotspots; WoSCC,"Bibliometrics; Biofilms; Environmental Pollutants; Fresh Water; Metals, Heavy","Environmental Pollutants; Metals, Heavy",National Natural Science Foundation of China (51879080); National Natural Science Foundation of China (52070072); National Natural Science Foundation of China (51509129); National Key Research & Development Program of China (2019YFC1804303),,http://dx.doi.org/10.1007/s11356-022-20238-6,35522418,10.1007/s11356-022-20238-6,,,0,001-386-861-983-75X; 001-873-732-635-976; 002-052-422-936-00X; 002-199-745-356-209; 002-967-827-913-397; 003-358-321-271-967; 004-224-721-030-807; 005-434-726-504-161; 005-924-923-207-627; 006-251-842-573-935; 006-792-635-379-71X; 008-660-470-348-242; 009-815-360-352-54X; 010-165-303-346-059; 010-475-576-191-762; 010-581-177-109-070; 011-761-973-341-641; 011-806-303-911-875; 011-856-668-231-333; 011-889-686-347-218; 013-354-053-079-34X; 013-507-404-965-47X; 013-553-935-078-586; 013-664-435-073-916; 013-956-663-903-242; 014-716-069-056-611; 015-298-009-864-884; 016-682-383-902-572; 016-776-797-863-777; 016-992-600-030-007; 017-226-924-811-102; 017-625-668-652-744; 017-721-675-871-03X; 018-660-653-758-394; 019-630-104-678-825; 021-088-770-230-517; 021-423-602-083-592; 021-560-639-723-46X; 021-828-445-641-102; 022-909-842-878-809; 024-649-235-747-801; 024-821-285-039-506; 026-104-348-031-386; 027-443-691-504-577; 028-178-234-252-29X; 028-649-352-920-218; 028-944-581-853-401; 029-881-546-258-069; 030-507-395-460-432; 032-044-720-562-550; 032-083-243-254-193; 039-619-633-913-155; 040-203-503-017-033; 042-156-500-822-073; 043-823-192-637-118; 045-452-458-870-447; 046-042-961-317-184; 047-693-265-542-551; 047-855-585-482-892; 048-786-972-792-727; 049-760-682-279-029; 050-394-923-777-116; 050-428-578-252-361; 051-640-667-904-645; 052-077-712-803-744; 052-489-799-018-036; 053-346-507-381-350; 053-584-455-180-509; 055-298-618-747-078; 056-848-673-462-235; 057-220-043-207-830; 058-075-745-693-157; 058-730-364-144-689; 059-313-703-818-502; 061-114-631-317-441; 062-933-251-230-243; 063-077-309-324-320; 063-278-461-185-362; 064-133-945-795-051; 065-451-028-962-502; 065-532-110-088-02X; 065-831-618-896-167; 066-479-148-432-750; 069-194-253-818-823; 070-454-648-844-00X; 070-535-063-725-384; 073-553-230-010-262; 074-312-057-493-49X; 080-057-298-189-263; 083-051-527-519-695; 084-134-740-234-007; 085-040-175-514-91X; 086-797-207-730-029; 087-732-515-324-38X; 089-972-743-942-505; 093-001-273-584-32X; 094-495-984-714-863; 098-715-786-816-049; 099-076-018-146-781; 101-920-067-191-790; 104-051-995-421-904; 111-724-798-443-706; 129-026-147-222-817; 133-304-343-704-567; 137-470-733-774-279; 138-388-089-003-548; 150-191-703-460-593; 151-822-238-214-235; 159-185-108-474-372; 167-214-624-634-774,10,false,, -005-554-356-955-50X,"Oil price shocks, stock market returns, and volatility spillovers: a bibliometric analysis and its implications.",2022-01-19,2022,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Muhammad Farhan Bashir,"The current research paper identifies the current dynamics in the oil price-stock market nexus to provide a research overview and suggest further research directions. We used bibliometrix R package to examine 684 studies to identify research trends in oil price shocks, stock market returns, and volatility spillover effects. We recognize the most influential authors, publications, and research institutions and their significance within the current scientific literature. We further analyzed research themes to observe impediments in the existing literature and suggest new research directions to summarize that disaggregated sectoral analysis and meta-analysis approach by including moderator analysis will broaden the research contribution in the future. Lastly, we conclude our investigation by identifying new research avenues.",29,16,22809,22828,Economics; Volatility (finance); Stock (firearms); Oil price; Stock market; Spillover effect; Financial economics; Moderation; Econometrics; Macroeconomics; Monetary economics; Computer science; Engineering; Mechanical engineering; Paleontology; Horse; Biology; Machine learning,Bibliometric analysis; Oil price shocks; Stock market returns; Volatility spillover,Bibliometrics; Economics; Humans,,,https://link.springer.com/content/pdf/10.1007/s11356-021-18314-4.pdf https://doi.org/10.1007/s11356-021-18314-4,http://dx.doi.org/10.1007/s11356-021-18314-4,35048345,10.1007/s11356-021-18314-4,,PMC8769094,0,000-857-359-726-856; 002-035-913-252-644; 003-011-384-423-822; 005-557-551-347-693; 006-449-034-569-384; 012-460-640-217-498; 013-425-159-910-299; 014-450-096-603-961; 015-249-067-927-117; 016-760-898-701-594; 017-593-056-757-920; 017-750-600-412-958; 021-591-029-325-220; 025-269-021-274-406; 025-519-330-303-53X; 028-197-550-031-150; 029-272-404-514-609; 032-289-388-877-539; 033-071-508-442-279; 035-088-549-633-681; 035-951-687-011-236; 041-803-994-243-910; 041-995-452-655-741; 042-280-739-309-27X; 043-704-478-691-214; 045-941-054-018-861; 047-609-755-194-129; 053-772-676-261-896; 054-818-565-070-154; 055-446-242-363-122; 055-643-484-535-268; 058-804-129-952-132; 058-954-751-093-474; 061-130-225-905-192; 062-924-701-093-115; 063-275-582-056-934; 069-171-221-225-474; 069-424-875-677-042; 073-137-791-895-360; 074-737-238-827-325; 080-086-540-953-374; 080-436-406-243-416; 083-668-122-332-435; 083-954-252-201-836; 091-579-345-619-703; 094-486-055-848-504; 098-277-541-959-490; 098-288-118-872-279; 098-372-834-725-191; 102-116-456-773-427; 104-495-326-573-684; 104-660-807-742-772; 107-881-898-256-419; 108-906-257-415-218; 109-009-854-081-734; 112-880-525-549-725; 114-462-436-028-670; 132-475-918-388-674; 135-801-632-218-493; 135-946-502-917-47X; 137-210-833-321-030; 141-346-017-560-516; 143-580-961-741-801; 144-610-300-951-917; 151-122-612-781-276; 160-721-312-702-338; 178-608-217-334-644,65,true,,green -005-638-250-129-638,"Worldwide trends in the scientific production on soccer players market value, a bibliometric analysis using bibliometrix R-tool",2022-06-30,2022,journal article,Team Performance Management: An International Journal,13527592,Emerald,United Kingdom,Maribel Serna Rodríguez; Ana María Ortega Alvarez; Leonel Arango-Vasquez,"; Purpose; This study aims to identify the current state, the emergent research clusters, the key research topics and the configuration of collaboration in scientific production related to the market value of soccer players.; ; ; Design/methodology/approach; This article analyzes 52 articles published between 1985 and 2021 and from the Scopus and WoS databases.; ; ; Findings; The subject is of growing interest both in academic and practical areas. A variable that frequently appears as a determinant of market value is crowd wisdom. The largest cluster related to the co-citation level shows that the main issues about soccer player market value are player performance, team performance, and the determinants of the superstar formation. Spain and Germany stand out as essential countries both in literary production and citation rate. The network of collaborations is still low.; ; ; Research limitations/implications; This study is supported by databases being constantly updated, resulting in continuous variation in the number of indexed journals. Consequently, a bibliometric analysis regarding an emergent topic can, in fewer years, be subject to essential variations. Another limitation is that it has analyzed a particular topic using the most influential databases, and the global perspective could be improved with the incorporation of other different databases. Data regarding collaborations could be helpful for investigations or policies that propose to approach the topic supported by specialized groups. This study offers the possibility for future researchers to extend the databases used, the level of analysis, or focus on specific topics or variables affecting the soccer player market value.; ; ; Originality/value; This study contributes to knowing the current state of the soccer player market value research. Studies on such topics are relatively limited concerning the literature review.; ",28,5/6,415,440,Originality; Scopus; Value (mathematics); Citation; Subject (documents); Production (economics); Computer science; Data science; Marketing; Sociology; Business; Political science; Economics; Social science; Library science; Qualitative research; MEDLINE; Machine learning; Law; Macroeconomics,,,,,,http://dx.doi.org/10.1108/tpm-02-2022-0015,,10.1108/tpm-02-2022-0015,,,0,002-596-427-175-559; 003-044-890-841-294; 009-697-466-157-588; 010-065-762-504-134; 013-507-404-965-47X; 015-018-003-825-199; 016-229-144-164-087; 021-302-101-541-97X; 023-552-982-598-718; 024-491-347-287-793; 031-599-930-611-085; 038-714-321-945-181; 042-502-018-092-913; 045-519-382-871-366; 051-647-739-244-271; 053-900-506-996-594; 054-818-565-070-154; 055-069-593-800-960; 056-781-413-322-89X; 058-093-837-385-759; 059-241-663-094-043; 063-326-560-074-32X; 065-516-419-444-125; 066-393-338-157-465; 072-979-020-254-543; 074-689-637-760-304; 082-902-108-397-757; 089-448-407-850-125; 092-744-355-005-580; 093-698-342-265-617; 097-415-202-428-368; 098-140-373-770-308; 103-048-590-116-828; 103-462-534-884-201; 104-919-753-218-202; 120-027-287-379-063; 121-645-188-193-41X; 124-187-743-925-055; 152-476-148-039-872; 188-653-111-189-712,12,false,, -005-791-483-622-475,Occurrence of pharmaceutically active compounds in groundwater and their effects to the human health.,2024-05-01,2024,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Natalia Klanovicz; Carolina Afonso Pinto,,31,23,33223,33238,Groundwater; Environmental health; Oxazepam; Toxicology; Prioritization; Environmental chemistry; Chemistry; Environmental science; Medicine; Biology; Business; Benzodiazepine; Geotechnical engineering; Biochemistry; Receptor; Process management; Engineering,Analgesics; Antibiotics; Predictive toxicity; Risk assessment; Water contamination,"Groundwater/chemistry; Humans; Water Pollutants, Chemical/analysis; Pharmaceutical Preparations/analysis; Environmental Monitoring; Carbamazepine/toxicity; Drinking Water/chemistry; Brazil","Water Pollutants, Chemical; Pharmaceutical Preparations; Carbamazepine; Drinking Water",Fundação de Apoio a Universidade de São Paulo,,http://dx.doi.org/10.1007/s11356-024-33423-6,38691293,10.1007/s11356-024-33423-6,,,0,002-320-990-678-73X; 004-979-432-648-876; 008-592-458-679-83X; 009-207-034-896-921; 009-752-054-216-317; 013-507-404-965-47X; 014-385-817-297-354; 017-710-121-900-747; 020-969-358-206-113; 021-008-970-034-876; 025-648-914-134-056; 036-665-751-556-468; 041-722-080-496-327; 045-457-285-314-639; 047-748-511-554-87X; 048-628-815-861-537; 050-276-385-380-48X; 059-280-222-486-975; 059-777-653-359-277; 059-896-852-762-861; 060-023-103-175-064; 066-621-010-308-022; 069-583-020-951-008; 078-061-513-208-368; 091-595-317-072-923; 098-216-709-466-341; 107-219-682-317-730; 116-650-858-976-612; 119-230-247-345-836; 131-098-317-237-224; 137-936-701-367-582; 146-885-353-976-275; 172-145-810-969-927,2,false,, -005-806-574-513-206,Trends and insights in health anxiety studies (2000–2025): a bibliometric analysis,2025-05-08,2025,journal article,Journal of Public Health,21981833; 16132238; 09431853,Springer Science and Business Media LLC,Germany,Masoud Imani; Mohammad Javad Shabani; Mohammadreza Pirmoradi; Hamid Mohsenabadi,,,,,,Anxiety; Public health; Environmental health; Bibliometrics; MEDLINE; Medicine; Psychology; Political science; Psychiatry; Computer science; Library science; Nursing; Law,,,,,,http://dx.doi.org/10.1007/s10389-025-02475-4,,10.1007/s10389-025-02475-4,,,0,000-062-079-580-777; 000-589-152-563-465; 000-667-231-896-402; 002-767-611-194-753; 004-744-858-451-345; 008-163-481-573-405; 009-686-088-732-595; 010-411-044-381-685; 018-323-572-748-832; 021-059-745-995-881; 023-248-229-978-378; 026-793-549-944-276; 027-825-062-708-802; 029-522-931-243-395; 034-924-263-035-787; 038-785-428-592-476; 040-079-846-811-225; 040-300-453-806-732; 047-134-478-431-993; 053-721-642-375-668; 057-048-072-874-411; 058-719-294-858-186; 062-422-182-436-402; 064-562-955-424-399; 069-017-072-964-269; 070-611-757-291-826; 072-484-962-614-712; 076-317-487-474-032; 082-737-938-204-823; 092-916-968-842-814; 115-400-856-508-665; 141-770-516-078-794; 147-107-749-256-018; 160-950-985-516-862; 189-237-009-934-409,0,false,, -005-821-647-221-999,Analysis of the scientific knowledge structure on automation in the wine industry: a bibliometric and systematic review,2024-04-29,2024,journal article,European Food Research and Technology,14382377; 14382385,Springer Science and Business Media LLC,Germany,Javier Martínez-Falcó; Eduardo Sánchez-García; Bartolome Marco-Lajara; Luis A. Millán-Tudela,"AbstractThe objective of this research is to analyze the knowledge structure of the academic literature indexed in the Core Collection of the Web of Science on automation in the wine industry, from the first registered article in 1996 to 2022, in order to identify the latest trends in the study of this subject. A bibliometric and systematic analysis of the literature was carried out. First, for the quantitative analysis of the scientific production, the bibliometric study was conducted, using the WoS database for data collection and the VosViewer and Bibliometrix applications to create the network maps. Second, once the literature had been examined quantitatively, content analysis was undertaken using the PRISMA methodology. The results show, among other aspects, the uneven distribution of the examined scientific production from 1996 to 2022, that computer vision, data aggregation, life cycle assessment, precision viticulture, extreme learning machine and collaborative platforms are the major current keywords and the predominance of Spain and Italy in terms of scientific production in the field. There are various justifications which support the originality of this study. First, it contributes to the understanding of academic literature and the identification of the most recent trends in the study of automation in the wine industry. Second, to the best of our knowledge, no prior bibliometric studies have considered this topic. Third, this research evaluates the literature from the first record to the year 2022, thereby providing a comprehensive analysis of the scientific production.",250,9,2273,2289,Scientific literature; Originality; Data science; Bibliometrics; Automation; Identification (biology); Subject (documents); Computer science; Systematic review; Knowledge management; Engineering; Social science; Sociology; Library science; Political science; MEDLINE; Mechanical engineering; Qualitative research; Paleontology; Botany; Law; Biology,,,,Universidad de Alicante,https://link.springer.com/content/pdf/10.1007/s00217-024-04553-5.pdf https://doi.org/10.1007/s00217-024-04553-5,http://dx.doi.org/10.1007/s00217-024-04553-5,,10.1007/s00217-024-04553-5,,,0,000-097-565-501-069; 002-569-907-824-390; 005-843-854-994-14X; 006-828-363-334-543; 007-154-761-363-68X; 007-421-318-689-873; 008-325-894-383-959; 008-672-397-440-576; 008-995-700-430-108; 009-461-775-402-865; 010-653-842-426-00X; 011-137-170-111-245; 012-244-273-151-91X; 014-516-435-326-890; 015-450-957-699-851; 015-845-067-533-469; 015-929-354-527-65X; 018-816-799-698-548; 019-571-002-529-995; 025-954-342-677-578; 027-587-124-037-127; 030-413-869-315-679; 030-853-071-539-98X; 032-552-233-175-060; 033-648-860-843-219; 035-146-490-761-138; 037-654-605-290-705; 038-893-423-625-214; 042-308-370-423-743; 043-724-004-409-043; 044-776-532-451-668; 045-290-531-661-774; 051-358-748-331-683; 051-696-804-332-739; 053-509-336-322-076; 055-408-480-483-325; 056-846-813-594-477; 059-402-222-489-319; 060-750-077-475-450; 061-970-121-962-012; 065-443-134-740-719; 068-128-594-192-388; 070-555-717-266-809; 081-964-440-929-37X; 082-036-634-875-28X; 086-351-746-485-054; 095-601-880-513-015; 103-334-615-909-451; 103-642-594-792-972; 108-080-677-515-356; 110-952-023-906-574; 114-571-117-217-549; 116-033-792-970-803; 128-450-178-423-626; 130-354-971-812-864; 134-472-676-914-473; 136-892-524-585-926; 149-670-928-974-264; 171-648-452-969-510; 179-624-400-834-934; 183-038-421-509-121; 195-478-848-330-280,17,true,cc-by,hybrid -005-821-797-348-32X,60 years' development of research on sociocultural theory: a bibliometric analysis,2025-03-12,2025,journal article,Current Psychology,10461310; 19364733,Springer Science and Business Media LLC,United States,Meisam Moghadam,,44,8,6592,6609,Psychology; Sociocultural evolution; Anthropology; Sociology,,,,,,http://dx.doi.org/10.1007/s12144-025-07652-y,,10.1007/s12144-025-07652-y,,,0,002-523-404-213-383; 003-103-703-899-739; 003-899-387-146-853; 007-125-931-049-78X; 008-331-105-022-968; 010-325-369-437-105; 010-423-006-392-744; 013-507-404-965-47X; 018-329-648-998-406; 020-704-421-153-082; 024-907-531-063-067; 025-302-119-966-613; 030-205-155-732-204; 030-564-769-109-809; 032-754-693-434-890; 034-098-499-992-450; 034-768-039-318-254; 034-878-857-689-951; 039-092-819-300-201; 045-460-327-792-813; 055-005-770-942-909; 064-400-499-357-900; 067-583-875-138-386; 077-196-072-914-532; 081-769-308-094-543; 088-789-338-635-913; 097-473-006-698-251; 102-196-754-118-589; 107-390-229-971-232; 125-173-725-255-640; 128-254-276-451-729; 158-119-273-686-844; 170-800-981-851-021; 194-268-913-626-546; 199-292-494-524-183,0,false,, -005-889-158-612-615,Effect of conservation agriculture on soil organic carbon sequestration in Mediterranean region. A systematic map.,2020-03-23,2020,other,,,Copernicus GmbH,,Tommaso Tadiello; Marco Acutis,"; &lt;p&gt;Conservation agriculture (CA) is characterized by minimal soil disturbance, permanent soil cover, and diversification of crop species, as stated by FAO in 2017. Many CA experiments, however, have been carried out so far, by taking into account only one or two of the three principles. Therefore, the meta-analyses recently published may fail in giving correct results about the CA effectiveness on agroecosystem variables, mostly on soil organic carbon (SOC) content or stock.&lt;/p&gt;&lt;p&gt;In preparation of conducting a meta-analysis, the present study was carried out to collect published results about the effect of the concurrent adoption of the three CA principles on SOC under Mediterranean climate with a systematic literature search in Scopus and Web of Science. Initially, a single nested query has been applied to both the database, using the Boolean operators, in order to include all the international literature about CA experiments and SOC variable without climate filter at this step. The resulting raw files were downloaded and merged in a unique dataframe using R software with &quot;Bibliometrix&quot; package&lt;sup&gt;1&lt;/sup&gt;, which is an open-source tool developed for bibliometric analysis. The use of merged dataframe has mainly two advantages: it allows an easy duplicate removal (847 records in our case) and a more detailed information research both automatic and manual. Bibliometrix indeed provides tools for bibliometric analysis and data matrices building for co-citation, coupling, and co-word analysis highlighting, for example, that in the European continent both Italy and Spain are the most productive countries on these topics. &lt;br&gt;With these possibilities, as a further step, a new sub dataframe has been extracted by using the K&amp;#246;ppen classification for Mediterranean climate (sub-climates, Csa/Csb/Csc), allowing a reduction of 32% of the records.&lt;/p&gt;&lt;p&gt;1) Aria, M., Cuccurullo, C., 2017. Bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11(4).&lt;/p&gt;&lt;div&gt;; &lt;div&gt;; &lt;div&gt;&amp;#160;&lt;/div&gt;; &lt;/div&gt;; &lt;/div&gt;; ",,,796,,Conservation agriculture; Environmental science; Soil carbon; Mediterranean climate; Agroforestry,,,,,https://ui.adsabs.harvard.edu/abs/2020EGUGA..22..796T/abstract https://meetingorganizer.copernicus.org/EGU2020/EGU2020-796.html,http://dx.doi.org/10.5194/egusphere-egu2020-796,,10.5194/egusphere-egu2020-796,3099074216,,0,,0,false,, -006-096-598-994-043,Preprocesamiento de publicaciones acerca de indentidad digital descentralizada y autgobernada.,2022-01-01,2022,dataset,Figshare,,,,Roberto Pava,Referencias en formato bibtex obtenidas de las bases de datos Scopus y WoS. Preprocesamiento con el paquete bibliometrix,,,,,Philosophy,,,,,https://figshare.com/articles/dataset/Referencias_sobre_SSI_obtenidas_en_formato_bibtex/19579492/6,http://dx.doi.org/10.6084/m9.figshare.19579492.v6,,10.6084/m9.figshare.19579492.v6,,,0,,0,true,cc-by,gold -006-348-680-389-30X,What's the role of kindness in the healthcare context? A scoping review.,2025-02-05,2025,journal article,BMC health services research,14726963,Springer Science and Business Media LLC,United Kingdom,Angela Greco; Laura G González-Ortiz; Luca Gabutti; Daniel Lumera,"The role of kindness in healthcare is receiving increased attention. Indeed, international research shows that a culture of kindness has a positive impact on healthcare organizations, healthcare staff members, and patients. Benefits include better patient outcomes, as well as a humanized work environment, which helps to prevent stress and burnout among healthcare workers. Studies across different settings suggest that healthcare managers need to foster not only technical and organizational skills, but also social skills such as empathy and kindness. The purpose of this scoping review is to provide an overview of the current research landscape regarding initiatives based on acts of kindness in healthcare organizations. We will also explore whether this is a topic of interest to academics, which countries have conducted the most research on the subject, the practical implications for healthcare management, and potential directions for future research.; This scoping review was conducted using the Arksey and O'Malley framework. A search was performed in the electronic databases ScienceDirect, Pubmed and Web of Science, to identify studies published in English between 1994 and 2023 describing or evaluating kindness-based interventions in the healthcare context. Based on the predefined eligibility criteria, screening and studies selection were performed. Data were extracted and analyzed descriptively to summarize the evidence.; 19 studies were analyzed and included in the review. The article assessment revealed four categories: 1) organizational culture; 2) burnout reduction and staff well-being; 3) staff education / training; and 4) communication and patient experience. Kindness in healthcare is a relatively new topic, but of great scientific interest. The countries most interested in the topic are English speaking (with a particular interest in category 2) and Western European, and the methodology most commonly used to investigate this topic is qualitative.; The need for additional research on kindness in healthcare arises from a complex and dynamic healthcare environment, where the concept of kindness holds the potential to revolutionize the quality of care and the well-being of healthcare providers. The interest of the various countries in the 4 thematic categories proposed by the study and the performance results of healthcare organizations promoting kindness compared to others without this focus also bear further consideration.; © 2025. The Author(s).",25,1,207,,Kindness; Health administration; Health informatics; Nursing research; Context (archaeology); Medicine; Health care; Public health; Nursing; Political science; Law; Paleontology; Biology,Compassion; Hospital; Humanization; Leadership; Performance,"Humans; Empathy; Organizational Culture; Health Personnel/psychology; Delivery of Health Care/organization & administration; Burnout, Professional/prevention & control",,,,http://dx.doi.org/10.1186/s12913-025-12328-1,39910597,10.1186/s12913-025-12328-1,,PMC11796266,0,001-915-352-284-492; 005-510-388-398-117; 006-375-752-596-177; 007-831-849-690-090; 008-051-240-173-148; 008-136-506-559-877; 009-337-102-169-909; 013-303-277-111-046; 013-507-404-965-47X; 014-946-524-517-058; 017-750-600-412-958; 017-887-685-054-826; 018-222-622-222-837; 019-839-241-404-406; 021-964-644-682-712; 022-615-572-313-23X; 026-567-804-963-234; 029-626-769-383-715; 044-722-963-690-982; 044-982-387-120-359; 045-077-429-099-591; 049-391-379-302-694; 052-197-279-485-226; 053-637-157-894-075; 054-159-894-171-769; 055-887-764-528-864; 064-808-476-206-797; 065-321-813-837-840; 068-870-604-368-639; 072-180-491-287-010; 073-805-595-069-396; 086-904-182-852-257; 088-346-152-450-133; 090-692-770-625-029; 091-861-418-733-830; 095-917-555-820-784; 098-007-553-921-668; 098-209-386-166-460; 098-616-557-116-512; 098-655-071-731-955; 099-202-190-358-887; 104-336-993-572-361; 106-037-162-088-264; 122-827-252-276-011; 136-639-601-733-98X; 146-856-949-121-347; 161-557-355-039-630; 161-570-259-232-218; 164-804-138-070-898; 165-611-814-868-332; 167-552-021-359-584; 194-808-494-238-868; 197-688-932-329-379,3,true,"CC BY, CC0",gold -006-679-253-417-798,A scientometric study of doctoral theses on the Roma in the Iberian Peninsula during the 1977–2018 period,2020-10-10,2020,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Norma Salgado-Orellana; Emilio Berrocal de-Luna; Calixto Gutiérrez-Braojos,,126,1,437,458,Higher education; Peninsula; Library science; Political science; Bibliometrics; Productivity; Citation; Period (music); Scientometrics; Social network,,,,"Consejo Nacional de Innovación, Ciencia y Tecnología",https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics126.html#Salgado-Orellana21 https://link.springer.com/article/10.1007/s11192-020-03723-y https://www.scilit.net/article/cb02cde04d05c9d340c66b2b3adae508 https://ideas.repec.org/a/spr/scient/v126y2021i1d10.1007_s11192-020-03723-y.html,http://dx.doi.org/10.1007/s11192-020-03723-y,,10.1007/s11192-020-03723-y,3092256848,,0,005-126-719-939-672; 005-326-882-127-89X; 005-335-536-148-57X; 009-347-459-513-214; 009-540-606-199-662; 010-757-550-934-543; 011-336-473-093-736; 013-507-404-965-47X; 022-216-505-196-813; 023-812-222-391-595; 028-022-428-881-026; 029-884-352-155-970; 030-004-453-398-32X; 030-835-468-369-22X; 031-986-137-105-187; 037-770-639-307-489; 048-268-578-936-34X; 054-728-473-952-329; 057-464-575-444-379; 059-602-266-588-075; 061-360-384-200-011; 062-419-082-264-095; 066-116-737-176-887; 069-213-384-232-348; 072-032-252-768-656; 081-964-459-709-027; 085-540-619-082-013; 085-672-820-255-953; 086-427-776-080-785; 087-003-302-303-657; 087-412-390-248-420; 087-640-516-275-69X; 090-424-292-656-750; 093-940-657-865-812; 095-698-885-437-780; 099-937-794-590-473; 101-056-252-156-189; 102-851-990-484-802; 104-471-442-618-177; 104-610-514-466-430; 105-247-147-842-395; 105-464-379-591-389; 108-465-438-709-812; 110-319-246-674-957; 112-961-163-734-302; 115-313-277-541-115; 116-873-626-381-757; 118-432-145-955-341; 126-303-991-695-058; 133-806-362-475-042; 135-416-436-495-580; 137-358-843-656-45X; 140-679-184-307-082; 141-842-483-902-539; 144-126-065-636-137; 170-336-013-910-948; 170-782-926-142-082; 175-255-183-662-411; 180-560-286-893-61X; 184-502-438-153-566,1,false,, -007-011-621-945-305,Bibliometric analysis of residual cardiovascular risk: trends and frontiers.,2023-11-28,2023,journal article,"Journal of health, population, and nutrition",20721315; 16060997,Springer Science and Business Media LLC,Bangladesh,Lin Wang; Sutong Wang; Chaoyuan Song; Yiding Yu; Yuehua Jiang; Yongcheng Wang; Xiao Li,"The presence of residual cardiovascular risk is an important cause of cardiovascular events. Despite the significant advances in our understanding of residual cardiovascular risk, a comprehensive analysis through bibliometrics has not been performed to date. Our objective is to conduct bibliometric studies to analyze and visualize the current research hotspots and trends related to residual cardiovascular risk. This will aid in understanding the future directions of both basic and clinical research in this area.; The literature was obtained from the Web of Science Core Collection database. The literature search date was September 28, 2022. Bibliometric indicators were analyzed using CiteSpace, VOSviewer, Bibliometrix (an R package), and Microsoft Excel.; A total of 1167 papers were included, and the number of publications is increasing rapidly in recent years. The United States and Harvard Medical School are the leading country and institution, respectively, in the study of residual cardiovascular risk. Ridker PM and Boden WE are outstanding investigators in this field. According to our research results, the New England Journal of Medicine is the most influential journal in the field of residual cardiovascular risk, whereas Atherosclerosis boasts the highest number of publications on this topic. Analysis of keywords and landmark literature identified current research hotspots including complications of residual cardiovascular risk, risk factors, and pharmacological prevention strategies.; In recent times, global attention toward residual cardiovascular risk has significantly increased. Current research is focused on comprehensive lipid-lowering, residual inflammation risk, and dual-pathway inhibition strategies. Future efforts should emphasize strengthening international communication and cooperation to promote the comprehensive evaluation and management of residual cardiovascular risk.; © 2023. The Author(s).",42,1,132,,Residual risk; Bibliometrics; Medicine; Original research; MEDLINE; Residual; Library science; Internal medicine; Political science; Computer science; Algorithm; Law,Bibliometric analysis; CiteSpace; Residual cardiovascular risk; VOSviewer,Humans; Risk Factors; Cardiovascular Diseases/etiology; Bibliometrics; Communication; Heart Disease Risk Factors,,National Natural Science Foundation of China (No. 82074388),https://jhpn.biomedcentral.com/counter/pdf/10.1186/s41043-023-00478-z https://doi.org/10.1186/s41043-023-00478-z,http://dx.doi.org/10.1186/s41043-023-00478-z,38017531,10.1186/s41043-023-00478-z,,PMC10683255,0,000-561-744-687-168; 000-924-796-527-801; 001-628-725-633-391; 001-985-860-481-621; 002-052-422-936-00X; 002-184-535-017-602; 003-080-972-873-503; 003-248-772-184-849; 003-446-301-313-373; 003-588-403-299-836; 003-733-109-564-916; 003-893-356-536-755; 005-962-975-563-823; 006-475-510-699-286; 006-719-208-686-458; 007-171-659-211-393; 007-500-155-247-91X; 008-104-208-793-44X; 009-004-318-562-472; 009-570-476-980-086; 010-169-978-565-442; 010-231-596-400-655; 010-903-395-736-637; 011-522-311-765-869; 013-261-296-086-031; 013-427-684-874-483; 013-507-404-965-47X; 013-712-356-982-023; 014-221-864-742-245; 014-607-184-149-52X; 015-608-365-889-966; 015-674-126-879-184; 016-131-140-039-371; 016-371-665-072-02X; 017-718-328-218-928; 020-003-713-361-375; 020-264-676-376-863; 022-109-340-960-727; 023-045-309-100-098; 023-058-486-234-09X; 024-721-950-984-56X; 025-913-253-401-712; 025-933-640-651-074; 026-558-536-922-246; 026-896-886-089-719; 027-676-711-888-828; 029-420-167-353-195; 030-070-794-161-879; 030-504-020-765-607; 030-642-330-145-302; 030-712-540-109-597; 036-027-396-756-986; 036-579-208-987-994; 037-520-112-329-022; 040-752-835-477-388; 040-993-506-916-72X; 042-309-824-410-301; 043-078-587-325-285; 043-981-103-765-593; 044-494-457-615-873; 045-953-204-011-744; 046-074-803-230-32X; 047-307-965-840-332; 048-174-669-815-327; 050-485-537-113-93X; 054-818-565-070-154; 055-125-449-142-098; 055-212-655-851-931; 055-227-084-874-25X; 055-343-659-618-344; 056-343-967-973-758; 058-312-584-244-815; 058-779-581-303-68X; 059-844-689-398-283; 061-245-320-055-579; 061-481-435-464-756; 061-860-650-179-886; 064-400-499-357-900; 064-482-912-103-288; 066-263-187-937-978; 069-029-386-673-120; 069-918-481-975-207; 078-189-052-458-569; 078-394-776-117-498; 079-534-458-825-710; 079-701-510-613-13X; 081-192-521-163-209; 081-617-425-788-306; 081-738-213-332-033; 082-187-680-550-230; 084-803-620-592-606; 085-332-803-862-849; 085-343-359-129-58X; 086-743-580-416-042; 088-468-761-817-768; 089-566-780-616-430; 091-014-703-573-146; 094-027-228-692-294; 097-537-873-783-577; 097-545-965-732-224; 098-988-939-997-615; 101-752-490-869-458; 102-263-043-840-169; 103-166-510-248-167; 108-860-707-778-817; 109-041-235-734-898; 109-188-959-302-763; 110-508-096-581-714; 110-611-411-428-505; 111-650-876-279-720; 113-013-060-565-848; 120-705-338-809-036; 128-326-604-449-362; 129-963-172-498-918; 137-462-017-693-160; 141-770-516-078-794; 143-838-369-928-760; 145-884-008-644-455; 148-247-501-462-812; 158-101-673-380-638; 158-405-286-819-682; 183-615-208-133-767; 188-072-948-405-418; 191-785-625-767-383; 193-110-599-560-81X; 197-761-550-454-658,6,true,"CC BY, CC0",gold -007-176-137-062-362,Bibliometric study and potential applications in smartphone-based digital images: A perspective from 2013 to 2024.,2025-04-01,2025,journal article,Food chemistry,18737072; 03088146,Elsevier BV,Netherlands,Marcela de Souza Zangirolami; Patrícia Valderrama; Oscar Oliveira Santos,,482,,144106,144106,Perspective (graphical); Data science; Computer science; Artificial intelligence,Chemometrics; Colorimetry; Foods; Quantification; RGB,Smartphone; Bibliometrics; Food Contamination/analysis,,National Council for Scientific and Technological Development; Coordination of Higher Education Personnel Improvement,,http://dx.doi.org/10.1016/j.foodchem.2025.144106,40188772,10.1016/j.foodchem.2025.144106,,,0,000-886-994-450-652; 002-449-461-987-569; 005-821-647-221-999; 006-220-678-890-40X; 006-386-243-367-839; 007-927-686-249-87X; 009-281-946-893-673; 010-424-302-862-485; 010-724-850-708-467; 010-743-907-373-623; 011-098-612-679-307; 013-507-404-965-47X; 018-673-492-502-269; 018-733-986-763-129; 019-205-628-549-832; 020-128-485-924-189; 020-294-155-413-814; 023-103-706-274-035; 023-247-825-322-354; 023-531-650-088-516; 025-026-697-085-457; 025-755-296-560-165; 026-212-628-999-306; 026-517-523-086-460; 027-356-328-643-278; 028-241-349-494-706; 028-407-944-428-612; 029-157-591-092-208; 029-369-880-208-312; 029-929-147-829-872; 030-460-375-370-338; 031-153-492-261-292; 032-231-579-409-410; 034-780-801-813-436; 040-064-827-526-670; 040-314-849-338-039; 045-838-532-692-522; 047-174-117-055-482; 050-270-474-668-891; 051-827-587-078-195; 055-495-489-214-787; 055-970-906-476-893; 057-263-475-281-508; 058-969-443-551-703; 061-944-834-988-248; 064-997-475-019-59X; 065-325-253-914-737; 067-626-514-747-984; 070-234-702-951-697; 072-072-900-661-651; 078-349-262-919-693; 078-887-851-971-930; 085-517-474-107-738; 086-905-518-482-419; 087-908-894-487-926; 089-485-811-161-842; 103-921-365-828-419; 105-187-664-734-913; 107-159-742-700-933; 107-619-012-624-101; 110-091-698-100-745; 116-303-539-827-349; 123-686-416-535-885; 135-843-181-395-33X; 139-531-398-742-999; 144-752-580-354-087; 151-141-939-013-432; 153-944-305-972-078; 154-706-893-085-469; 156-279-319-105-751; 162-878-874-029-796; 165-189-363-777-27X; 165-536-569-671-159; 176-649-628-617-399; 188-454-790-940-210; 197-896-487-527-006,0,false,, -007-487-759-470-799,"Competencia digital, profesorado y educación superior",2023-02-08,2023,journal article,HUMAN REVIEW International Humanities Review / Revista Internacional de Humanidades,26959623,,,Andrés Santiago Cisneros Barahona; Luis Marqués Molías; Nicolay Samaniego-Erazo; María Isabel Uvidia Fassler; Wilson Castro-Ortiz; Henry Mauricio Villa-Yánez,"Haciendo uso de paquete informático Bibliometrix y de la Guía Prisma, se desarrolló un análisis bibliométrico de la literatura proveniente de la Web of Science sobre la competencia digital docente universitaria. Se delimita la investigación a través de tesauros de Eric. Se plantearon preguntas de investigación relacionadas con las fuentes de datos, los autores y las redes de colaboración. La investigación evidencia incrementos en la producción a partir del año 2019, la nacionalidad de los autores y la filiación de instituciones resaltan a través de redes de investigaciones extendidas en Iberoamérica. Es necesario ampliar este estudio a otras bases científicas.",12,Monográfico,1,20,Humanities; Political science; Philosophy,,,,,https://journals.eagora.org/revHUMAN/article/download/4680/3001 https://doi.org/10.37467/revhuman.v12.4680,https://journals.eagora.org/revHUMAN/article/download/4680/3001,,,,,0,,0,true,,bronze -007-685-813-636-217,A scientometric analysis of entrepreneurial and the digital economy scholarship: state of the art and an agenda for future research,2023-10-13,2023,journal article,Journal of Innovation and Entrepreneurship,21925372,Springer Science and Business Media LLC,,Natanya Meyer; Foued Ben Said; Nasser Alhamar Alkathiri; Mohammad Soliman,"AbstractRecently, there has been a greater focus on the relationship between entrepreneurship and the digital economy in academia and practice. However, no known work systematically reviews and analyses such a connection, which highlights the need to address this gap by conducting a thorough systematic literature review employing bibliometric and scientometric analyses concerning entrepreneurship and digital economy research. In doing so, analysis of key trends as well as knowledge structure (i.e., intellectual and conceptual) has been employed to analyze, visualize, and map 275 documents gathered from Web of Science (WoS) and Scopus data sets. The number of publications in the current research field has expanded dramatically due to the substantial efforts by major contributors (e.g., researchers, institutions, nations, and academic journals) worldwide. Key research themes, trends, approaches, and outlines were also emphasized by mapping the intellectual, social, and conceptual structures of entrepreneurship and digital economy-related research. The implications, limitations, and agenda for future research were all outlined.",12,1,,,Scopus; Entrepreneurship; Scholarship; Digital economy; Field (mathematics); Web of science; Sociology; Conceptual framework; Knowledge management; Social science; Data science; Regional science; Political science; Computer science; Mathematics; MEDLINE; Pure mathematics; Law,,,,,https://innovation-entrepreneurship.springeropen.com/counter/pdf/10.1186/s13731-023-00340-w https://doi.org/10.1186/s13731-023-00340-w,http://dx.doi.org/10.1186/s13731-023-00340-w,,10.1186/s13731-023-00340-w,,,0,000-180-554-769-219; 001-526-561-468-854; 002-052-422-936-00X; 002-876-135-588-972; 003-701-428-186-40X; 004-494-037-780-185; 005-528-910-008-624; 008-190-777-387-859; 008-417-185-917-514; 009-007-421-701-622; 009-901-977-938-074; 011-447-247-214-44X; 013-507-404-965-47X; 015-098-569-195-264; 015-737-038-893-598; 022-831-151-640-650; 022-907-477-999-768; 023-980-384-362-802; 024-187-200-384-293; 024-372-927-940-590; 027-690-220-065-414; 031-534-617-552-587; 034-895-270-779-354; 035-641-671-203-459; 041-187-375-102-530; 042-750-844-433-719; 045-368-114-501-494; 046-992-864-415-70X; 051-493-551-536-097; 051-913-040-573-871; 054-338-756-403-844; 055-108-058-430-581; 055-848-993-624-073; 059-128-948-055-73X; 065-302-089-334-121; 071-191-154-731-018; 071-417-719-561-458; 072-112-930-268-926; 072-740-252-932-732; 086-133-520-865-921; 087-529-175-193-737; 089-845-002-508-347; 093-199-388-383-137; 093-463-783-405-084; 098-080-683-385-120; 099-629-390-094-76X; 101-752-490-869-458; 102-552-670-274-152; 104-926-052-026-246; 105-519-621-171-872; 109-212-362-280-44X; 111-496-657-342-82X; 111-996-715-337-895; 113-380-694-799-077; 115-653-094-973-59X; 117-748-726-567-173; 124-069-328-079-982; 125-436-275-173-024; 130-118-481-726-299; 133-667-418-976-528; 137-256-950-929-321; 142-699-387-067-243; 148-255-738-772-990; 150-777-091-729-536; 153-609-219-955-708; 162-037-634-091-551; 168-334-954-183-796; 175-211-189-928-247,14,true,cc-by,gold -008-240-278-705-245,Sustainable Marketing: Insights on Current and Future Research Directions-A Bibliometric Analysis,2025-01-23,2025,journal article,Journal of Business & Tourism,25210548; 25200739,"Abdul Wali Khan University Mardan, Pakistan",,null Dr. P.S. Buvaneswari; null AISHWARYAA,"This study analyzes the existing research on sustainable marketing in the areas of commerce, management, tourism, and services. 431 articles were retrieved from the Dimensions AI database by applying the inclusion and exclusion criteria of the PRISMA model. Bibliometric tools, including R-Bibliometrix Biblioshiny and VOSviewer, were employed to examine publication trends, influential contributors, current themes, and future directions in the field. The analysis reveals a significant increase in publications post-2018. “Towards Sustainability: The Third Age of Green Marketing” emerges as the most cited work, and Kim K H is found to be an influential author. Evolving themes such as “Institutionalization” and “Macromarketing” offer great opportunities for future research studies. This study also provides valuable scope for policymakers to make strategic decisions in business for sustainable marketing.",10,2,1,21,Current (fluid); Marketing research; Data science; Regional science; Political science; Management science; Marketing; Business; Geography; Computer science; Engineering; Electrical engineering,,,,,https://www.jbt.org.pk/index.php/jbt/article/download/298/230 https://doi.org/10.34260/jbt.v10i02.298,http://dx.doi.org/10.34260/jbt.v10i02.298,,10.34260/jbt.v10i02.298,,,0,,0,true,cc-by,hybrid -008-264-990-323-888,Blue Economy Beyond Maritime Economics,2022-09-09,2022,book chapter,Power and the Maritime Domain,,Routledge,,Thauan Santos,"This chapter analyses different concepts associated with economic activities related to the seas and oceans. Based on a bibliometric literature review, it first uses the Bibliometrix package to investigate metadata, followed by Biblioshiny tool for data analysis, using Scopus and Web of Science databases and covering the 1959–2020 period. The main results focus on spatial and temporal dispersion of publications, main sources, authors and institutions, relevant and frequent words, and trend topics related to the issue. The conceptual discussion debates the concepts of blue economy, maritime economics, maritime cluster, economy of the sea, marine economy, and ocean governance together, bringing them up and away. Among the main conclusions, this discussion broadens in terms of relevance, number of publications, agenda, and stakeholders, moving from a biological to a governance approach.",,,215,232,Scopus; Corporate governance; Relevance (law); Metadata; Regional science; Economy; Web of science; Political science; Geography; Economics; World Wide Web; Computer science; Management; MEDLINE; Law,,,,,,http://dx.doi.org/10.4324/9781003298984-18,,10.4324/9781003298984-18,,,0,,0,false,, -008-494-638-374-778,A Bibliometric Analysis of the International Journal of Energy Economics and Policy: 2013-2022,2023-09-16,2023,journal article,International Journal of Energy Economics and Policy,21464553,EconJournals,Turkey,Sandip Solanki; Seema Singh; Meeta Joshi,"This paper performs a bibliometric analysis of the International Journal of Energy Economics and Policy (IJEEP) for 2013-2022. Bibliometrix R package (R studio) and Scopus database were used for the study and examined 2194 documents published in the journal between 2013-2022. The results showed an upward trend in publications with a yearly growth rate of 21.92%. H. Mahmood is the most relevant author by the number of papers published with the highest h-index, while the most-cited author is A. Mikhaylov. This research revealed that Indonesia is the most productive country in terms of publications, while Malaysia is the most-cited nation. Covenant University is the most productive university in terms of overall publications. The results show that there are 4782 authors’ keywords in total. Of these keywords, “economic growth” is the top keyword, with more than 293 occurrences. Intellectual and social structures highlighted collaborations amongst authors, institutes and countries.",13,5,260,270,Scopus; Web of science; Index (typography); Covenant; Library science; Bibliometrics; Energy analysis; Political science; Regional science; Social science; Sociology; Energy (signal processing); Computer science; Statistics; Law; World Wide Web; Mathematics; MEDLINE,,,,,https://econjournals.com/index.php/ijeep/article/download/14704/7479 https://doi.org/10.32479/ijeep.14704,http://dx.doi.org/10.32479/ijeep.14704,,10.32479/ijeep.14704,,,0,,3,true,cc-by,gold -008-613-829-211-938,Bibliometric analysis of climate change and water quality,2023-06-19,2023,journal article,Hydrobiologia,00188158; 15735117,Springer Science and Business Media LLC,Netherlands,Jin Gao; Shiying Zhu; Dehao Li; Haibo Jiang; Guangyi Deng; Yang Wen; Chunguang He; Yingyue Cao,,850,16,3441,3459,Climate change; Environmental science; Environmental resource management; Water quality; China; Water resources; Water resource management; Environmental planning; Geography; Ecology; Biology; Archaeology,,,,the National Natural Science Foundation of China; the National Natural Science Foundation of China; National Key Research and Development Program of China; Jilin Environmental Protection Scientific Research Project,,http://dx.doi.org/10.1007/s10750-023-05270-y,,10.1007/s10750-023-05270-y,,,0,000-403-776-688-583; 000-897-073-668-191; 002-052-422-936-00X; 006-533-011-854-491; 008-889-235-360-992; 010-127-799-953-858; 011-268-610-509-995; 013-507-404-965-47X; 014-371-443-569-097; 015-241-022-477-216; 017-168-665-145-092; 024-280-515-739-980; 024-391-080-411-151; 025-317-170-879-648; 026-161-400-903-032; 026-395-112-558-483; 027-237-558-039-20X; 031-749-315-161-474; 033-018-950-128-175; 034-093-957-911-935; 034-732-800-713-242; 036-575-094-219-787; 038-825-515-094-209; 039-462-750-859-60X; 039-768-419-803-245; 043-526-599-260-198; 043-656-622-021-474; 046-331-819-263-833; 047-178-865-362-101; 047-915-240-613-449; 050-770-044-158-200; 050-871-554-813-538; 051-451-914-117-364; 052-370-610-059-101; 053-494-071-710-268; 062-217-244-724-504; 066-263-089-858-934; 068-128-560-667-891; 068-385-738-959-291; 070-545-073-050-172; 072-433-366-531-363; 073-082-273-252-175; 073-426-945-644-400; 079-679-789-158-219; 080-763-052-807-971; 082-283-092-845-702; 083-357-955-847-347; 089-476-183-654-077; 089-484-024-427-117; 093-480-434-215-260; 096-664-013-835-651; 097-223-010-921-16X; 098-287-683-945-958; 101-752-490-869-458; 107-214-829-727-388; 108-022-733-270-037; 108-337-287-967-18X; 109-571-906-128-687; 117-334-961-162-491; 120-694-371-008-141; 122-472-505-645-066; 124-091-144-821-725; 124-259-474-610-484; 125-886-140-299-226; 130-371-848-783-126; 132-723-851-457-646; 135-271-237-178-318; 137-155-822-806-949; 140-003-495-999-899; 149-404-002-886-840; 151-698-363-273-159; 153-579-609-410-186; 161-122-165-126-124; 172-353-758-744-865; 172-754-265-198-808; 172-917-511-478-439; 177-442-489-217-595; 180-572-065-778-86X; 182-170-358-978-76X; 183-545-069-992-244,13,false,, -008-627-762-027-841,Role of AI/ML in the Study of Autism Spectrum Disorders: A Bibliometric Analysis,2024-03-01,2024,journal article,Journal of Technology in Behavioral Science,23665963,Springer Science and Business Media LLC,,A. Jiran Meitei; Bibhuti Bhusan Mohapatra; Budhachandra Khundrakpam; Nongzaimayum Tawfeeq Alee; Gulshan Chauhan,,9,4,809,824,Autism; Psychology; Spectrum (functional analysis); Clinical psychology; Developmental psychology; Physics; Quantum mechanics,,,,,,http://dx.doi.org/10.1007/s41347-024-00397-8,,10.1007/s41347-024-00397-8,,,0,001-948-371-333-799; 001-981-736-184-955; 004-446-226-001-068; 005-346-056-844-748; 006-470-801-818-123; 009-460-505-180-233; 009-740-076-661-739; 011-308-319-218-694; 011-769-713-389-418; 013-507-404-965-47X; 014-186-722-356-874; 016-958-826-144-462; 017-258-251-426-686; 019-494-633-618-090; 022-087-569-767-277; 024-366-529-943-760; 025-609-292-343-993; 026-431-457-303-844; 026-466-816-212-136; 026-575-386-496-388; 026-800-374-789-261; 031-176-990-740-730; 032-286-997-099-759; 032-614-895-376-073; 035-953-579-141-278; 038-071-828-158-105; 040-052-073-783-575; 050-919-612-083-992; 057-774-604-014-719; 060-498-805-987-859; 062-251-576-441-614; 067-665-073-115-085; 068-247-750-230-457; 075-436-583-892-459; 077-201-397-653-514; 080-691-153-524-188; 086-034-655-694-249; 088-222-088-180-313; 089-391-671-389-951; 094-385-219-750-616; 101-256-916-999-40X; 101-752-490-869-458; 101-983-418-861-53X; 102-355-475-363-528; 104-204-960-134-387; 105-554-398-641-176; 122-415-544-444-960; 123-498-859-171-509; 131-423-542-523-282; 132-701-177-016-971; 172-499-182-561-290,1,false,, -008-633-740-069-654,"Unveiling the dynamic landscape of artificial intelligence in attention-deficit/hyperactivity disorder (ADHD) research: a comprehensive analysis of trends, intellectual structure, and thematic evolution",2025-02-10,2025,journal article,Current Psychology,10461310; 19364733,Springer Science and Business Media LLC,United States,Manal Mohamed Elhassan Taha; Siddig Ibrahim Abdelwahab; Ieman A. Aljahdali; Omar Oraibi; Bassem Oraibi; Hassan Ahmad Alfaifi; Amal Hamdan Alzahrani; Abdullah Farasani; Ahmed Ali Jerah; Yasir Osman Hassan Babiker,,44,9,8068,8081,Psychology; Attention deficit hyperactivity disorder; Thematic map; Thematic analysis; Attention deficit; Cognitive psychology; Clinical psychology; Cartography; Social science; Qualitative research; Geography; Sociology,,,,Jazan University,,http://dx.doi.org/10.1007/s12144-025-07420-y,,10.1007/s12144-025-07420-y,,,0,002-052-422-936-00X; 002-694-157-904-713; 005-962-986-743-408; 009-132-265-301-952; 012-114-389-955-80X; 013-507-404-965-47X; 014-983-298-710-257; 015-215-890-668-945; 015-542-128-816-289; 019-285-108-152-607; 020-353-909-219-530; 020-932-481-152-393; 023-580-489-650-023; 026-140-950-796-11X; 036-545-483-832-828; 039-253-107-335-945; 040-390-812-155-313; 042-832-250-054-710; 043-840-112-460-936; 044-151-611-794-538; 047-831-787-177-195; 048-359-304-409-01X; 051-738-703-416-549; 052-219-583-377-865; 053-797-217-895-719; 055-502-068-006-149; 056-580-340-920-934; 059-390-846-564-086; 060-612-658-594-524; 061-234-210-302-598; 061-644-920-300-484; 063-575-482-280-933; 064-063-613-504-181; 065-781-223-090-115; 072-788-038-029-211; 076-498-170-063-038; 078-137-208-559-215; 101-908-788-996-677; 110-088-351-722-011; 124-940-763-918-829; 127-076-447-863-74X; 134-464-945-370-831; 145-463-828-118-519; 167-633-547-380-374; 172-149-619-340-766,0,false,, -008-665-586-276-562,"The research landscape of bipolar disorder in Germany: productive, but underfunded.",2024-06-15,2024,journal article,International journal of bipolar disorders,21947511,Springer Science and Business Media LLC,Germany,Cindy Eckart; Andreas Reif,"The recurrent mental illness bipolar disorder is a major burden on the healthcare system, which underlines the importance of research into this disease. Germany is one of the most productive countries in this research activity. This bibliometric analysis aims to outline the social and conceptual structure of the German research landscape on bipolar disorder over the last decade. Furthermore, we provide a short overview over current public funding.; Concerning the social structure, most of the German publications were collaboration projects, both with a national but also international orientation, in the latter case predominantly with countries of the global North. Analysis of the conceptual structure of German research activity identified psychiatric genetics, early recognition of bipolar disorder, neuroimaging, and pharmacological interventions as important topics within the field. In the context of a survey, only few publicly funded research projects were reported, many of which did not exclusively investigate bipolar disorder but followed a transdiagnostic approach.; Our bibliometric analysis revealed internationally well-networked German research activities on bipolar disorder. In stark contrast to its high prevalence and correspondingly high financial burden to the healthcare system, current grant support for research on this illness is strikingly low, particularly concerning the development of novel treatments.; © 2024. The Author(s).",12,1,22,,Bipolar disorder; German; Public health; Mental illness; Psychiatry; Neurology; Psychology; Mental health; Political science; Medicine; Social science; Sociology; Cognition; Geography; Nursing; Archaeology,Bibliometric analysis; Bipolar disorder; Germany; Research landscape,,,"Johann Wolfgang Goethe-Universität, Frankfurt am Main",https://journalbipolardisorders.springeropen.com/counter/pdf/10.1186/s40345-024-00344-9 https://doi.org/10.1186/s40345-024-00344-9,http://dx.doi.org/10.1186/s40345-024-00344-9,38878206,10.1186/s40345-024-00344-9,,PMC11180073,0,005-818-679-161-743; 013-507-404-965-47X; 019-220-345-831-067; 027-602-319-059-214; 030-281-311-115-246; 039-075-286-427-271; 040-079-846-811-225; 057-922-193-572-485; 072-240-104-949-259; 079-148-609-824-147; 080-833-908-502-181; 114-169-125-889-884; 123-042-446-517-334; 144-282-757-784-40X; 171-203-546-806-93X,1,true,cc-by,gold -008-977-871-526-885,Ecology and sustainability of the Inner Mongolian Grassland: Looking back and moving forward,2020-08-01,2020,journal article,Landscape Ecology,09212973; 15729761,Springer Science and Business Media LLC,United States,Qing Zhang; Alexander Buyantuev; Xuening Fang; Peng Han; Ang Li; Frank Yonghong Li; Cunzhu Liang; Qingfu Liu; Qun Ma; Jianming Niu; Chenwei Shang; Yongzhi Yan; Jing Zhang,,35,11,2413,2432,Climate change; Ecology; Geography; Sustainability science; Ecology (disciplines); Sustainable development; Land management; Sustainability; Landscape planning; Landscape ecology,,,,National Natural Science Foundation of China; Key Science and Technology Program of Inner Mongolia; Key Science and Technology Program of Inner Mongolia; Natural Science Foundation of Inner Mongolia; Grassland Talents Program of the Inner Mongolia,https://link.springer.com/content/pdf/10.1007/s10980-020-01083-9.pdf,http://dx.doi.org/10.1007/s10980-020-01083-9,,10.1007/s10980-020-01083-9,3046425751,,0,001-119-042-516-211; 001-477-251-841-416; 001-554-753-147-797; 002-896-586-717-903; 004-819-527-814-707; 005-659-754-810-307; 006-808-502-767-966; 009-247-419-107-90X; 011-104-666-786-86X; 011-212-717-227-207; 013-507-404-965-47X; 013-524-854-219-241; 015-121-543-559-579; 020-019-480-536-336; 020-974-374-753-594; 021-457-487-289-725; 022-773-402-612-695; 023-572-576-650-814; 025-502-491-717-919; 025-724-371-625-802; 026-321-506-010-590; 026-942-697-842-390; 029-317-563-787-838; 029-632-455-149-505; 030-181-618-626-712; 030-687-895-806-920; 031-026-882-186-863; 031-682-562-372-670; 033-648-918-097-117; 037-738-287-581-889; 039-466-400-216-928; 041-479-199-830-903; 043-625-557-749-992; 044-004-720-559-326; 045-855-332-989-131; 047-098-139-066-834; 049-732-230-170-745; 050-133-185-426-473; 050-639-477-290-449; 053-497-231-388-559; 055-001-884-465-620; 055-381-706-199-769; 055-549-817-869-637; 057-445-060-349-782; 063-883-451-963-306; 068-697-386-564-343; 069-519-685-166-155; 071-467-180-228-138; 072-426-115-241-104; 073-442-839-754-315; 074-486-746-551-018; 078-541-265-023-796; 090-473-965-082-271; 093-906-305-232-940; 102-317-975-047-997; 102-991-940-398-345; 105-479-096-395-312; 105-651-959-499-62X; 111-722-349-475-076; 114-615-524-468-187; 115-225-712-781-683; 118-253-846-983-27X; 119-680-740-449-688; 119-965-983-628-559; 121-262-042-451-633; 125-355-958-689-084; 139-321-340-381-566; 141-418-138-598-051; 142-555-229-911-83X; 144-245-305-013-88X; 146-319-131-227-504; 146-489-772-555-964; 149-761-972-618-05X; 151-472-689-623-508; 161-126-001-622-138; 164-628-239-332-404; 164-959-949-015-450; 170-834-853-019-439; 173-095-526-475-034; 176-746-590-424-616,59,false,, -008-981-543-546-782,Comprehensive Science Mapping Analysis [R package bibliometrix version 3.0.4],2021-01-19,2021,,,,,,Massimo Aria; Corrado Cuccurullo,,,,,,Programming language; R package; Science mapping; Computer science,,,,,,,,,3161240280,,0,,0,false,, -009-102-027-975-401,PIAAC Survey of Adult Skills: A review of the research landscape,2025-05-26,2025,journal article,International Review of Education,00208566; 15730638,Springer Science and Business Media LLC,Netherlands,Débora B. Maehler; Daniel Hernández-Torrano; Matthew G. R. Courtney; Franzisca P. Fischer; Luca F. Hollricher; Julia Gorges,"Abstract; The Programme for the International Assessment of Adult Competencies (PIAAC) of the Organisation for Economic Co-operation and Development (OECD) has transformed international research and policy debates on the assessment of adult skills. Although research using PIAAC data is accumulating, little is known about how these data are used and what they contribute to developing the various disciplines interested in adult skills. In this study, a data-driven approach was used to examine PIAAC-based international research to date. Drawing on a comprehensive analysis of 880 publications, the review found that the field of PIAAC research is young and geographically diverse, with dominant contributions from the United States and Germany. While PIAAC research relies on a broad pool of researchers with high collaboration rates, only a quarter of publications involve international collaboration. The analyses also revealed that the development of the field is based on four interrelated disciplines (education, sociology, psychology and economics) and three differentiated historical paths: theoretical and methodological approaches to the measurement of adult skills, cognitive skills and problem solving in technology-rich environments at the workplace, and the role of adult literacy skills for societal and economic development. Moreover, the PIAAC literature addresses a broad range of topics, including cognitive, non-cognitive and basic skills (e.g. literacy and numeracy), human capital, occupational mismatch, migration, “returns to skills”, informal learning and large-scale assessment methodologies. Implications for further development of PIAAC research for users of PIAAC data, data-providing institutions and policymakers are discussed.",,,,,Geography; Psychology; Regional science; Sociology,,,,Bundesministerium für Bildung und Forschung; GESIS – Leibniz-Institut für Sozialwissenschaften e.V.,,http://dx.doi.org/10.1007/s11159-024-10123-4,,10.1007/s11159-024-10123-4,,,0,001-611-182-422-959; 004-899-504-715-135; 005-827-745-751-376; 005-911-229-931-719; 007-279-438-013-013; 007-909-548-747-644; 008-964-559-383-370; 009-088-812-043-927; 010-194-028-604-828; 012-030-936-447-487; 013-507-404-965-47X; 014-139-101-027-718; 014-154-801-914-479; 014-653-792-441-732; 017-891-573-760-357; 019-128-299-119-244; 025-487-528-665-364; 027-492-194-155-91X; 031-723-628-635-858; 036-234-219-347-120; 036-883-207-978-224; 037-416-487-612-318; 037-815-640-424-494; 040-960-845-600-104; 045-422-273-148-899; 045-846-203-260-235; 047-772-736-381-957; 048-530-913-399-838; 049-640-672-133-636; 050-638-960-239-454; 055-781-625-349-393; 056-116-545-069-283; 057-888-580-994-825; 060-600-010-231-925; 061-224-005-101-843; 065-010-405-236-060; 080-334-803-676-699; 085-349-312-023-558; 085-423-816-275-911; 088-050-594-893-262; 089-847-019-452-860; 089-888-753-187-062; 090-710-960-869-362; 091-132-080-261-37X; 092-498-441-912-872; 101-507-402-778-865; 102-853-522-902-750; 124-089-382-014-491; 125-428-611-593-678; 128-129-508-695-958; 129-469-632-308-940; 140-071-244-823-383; 140-493-145-525-356; 141-033-416-052-773; 145-463-949-203-47X; 153-478-294-217-556; 156-025-220-414-730; 174-154-021-114-94X,0,true,cc-by,hybrid -009-478-148-751-979,Bibliometric review on FDI attractiveness factors,,2022,journal article,European J. of International Management,17516757; 17516765,Inderscience Publishers,United Kingdom,Vanessa P.G. Bretas; Ilan Alon; Andrea Paltrinieri; Kavilash Chawla,"This article reviews the literature on foreign direct investment (FDI) attractiveness factors through bibliometric and content analyses. We analyse 499 articles between 1994 and 2021 extracted from the Web of Science database. Using Bibliometrix R-package and VOSviewer software, we combined co-citation, bibliographic coupling, and keyword co-occurrence temporal analysis with a content analysis of the most cited articles. Five main research categories are revealed: structure for FDI, market conditions, entry conditions, institutional framework, and resources offer. We propose a conceptual framework of FDI attractiveness factors aligned with FDI motives. The article comprehensively reviews the key determinants using quantitative and qualitative approaches and provides future research directions.",17,2/3,469,469,Attractiveness; Foreign direct investment; Citation; Web of science; Business; Regional science; Computer science; Political science; Sociology; World Wide Web; Psychology; MEDLINE; Psychoanalysis; Law,,,,,https://uia.brage.unit.no/uia-xmlui/bitstream/11250/2996956/4/Article.pdf https://hdl.handle.net/11250/2996956,http://dx.doi.org/10.1504/ejim.2022.120721,,10.1504/ejim.2022.120721,,,0,,12,true,cc-by,hybrid -009-665-142-413-69X,Scientific Radiography of Healthcare System Process Efficiency Digitalisation,2023-11-01,2023,journal article,Zagreb International Review of Economics and Business,18491162,Walter de Gruyter GmbH,,Oana-Ramona Lobonț; Alexandra-Mădălina Țăran; Sorana Vătavu; Iulia Para,"Abstract; Digitalisation remains a complex process in terms of integration into healthcare, a significant challenge worldwide. This study aims to identify the most influential trends in terms of authors, sources, countries, affiliations, and highly engaged documents that significantly contribute to the healthcare system’s digitalisation. To perform a comprehensive science mapping analysis, a logical data frame of 336 Web of Science database recent papers published between 2018 and 2022 are analysed using R-Bibliometrix. Our results highlighted throughout a scientific mapping and visual framework that digitalisation of the health-care system is a revolutionary, actual, and pervasive concept, considered a new research area recognised by evolution and consistent growth. Moreover, the results provide different types of networks and highlight the keywords, authors, documents, and countries with the highest interest in the subject of the digitalisation of healthcare.",26,2,113,136,Health care; Process (computing); Subject (documents); Healthcare system; Frame (networking); Knowledge management; Computer science; Data science; Political science; World Wide Web; Telecommunications; Law; Operating system,,,,,https://sciendo.com/pdf/10.2478/zireb-2023-0017 https://doi.org/10.2478/zireb-2023-0017 https://hrcak.srce.hr/file/448063 https://hrcak.srce.hr/310423,http://dx.doi.org/10.2478/zireb-2023-0017,,10.2478/zireb-2023-0017,,,0,000-430-589-057-480; 000-848-264-004-813; 007-303-744-283-115; 012-466-164-683-056; 017-750-600-412-958; 025-051-075-176-471; 026-798-954-453-721; 045-255-786-565-983; 063-899-593-085-461; 079-388-097-137-118; 123-202-581-406-928; 152-178-639-985-956; 167-917-040-153-230; 183-891-112-474-445; 192-812-471-639-393; 194-472-925-655-625,1,true,cc-by-nc-nd,hybrid -010-065-762-504-134,"Worldwide trends in the scientific production on rural depopulation, a bibliometric analysis using bibliometrix R-tool",,2020,journal article,Land Use Policy,02648377,Elsevier BV,Netherlands,Rocío Rodríguez-Soler; Juan Uribe-Toril; Jaime de Pablo Valenciano,,97,97,104787,,Regional science; Field (geography); Geography; Scientific production; Bibliometric analysis; Sample (statistics); Scopus; Metadata,,,,,https://www.sciencedirect.com/science/article/pii/S0264837719314450 https://dialnet.unirioja.es/servlet/articulo?codigo=7592128,http://dx.doi.org/10.1016/j.landusepol.2020.104787,,10.1016/j.landusepol.2020.104787,3036656090,,0,001-362-109-580-42X; 001-619-469-226-708; 002-100-753-125-58X; 002-305-466-249-191; 003-868-159-017-396; 005-010-402-064-666; 005-274-961-512-559; 005-518-989-372-410; 007-243-072-361-51X; 007-265-256-687-706; 007-603-635-345-908; 007-839-905-160-868; 007-884-468-715-433; 008-227-012-268-686; 011-236-836-338-790; 011-440-720-326-884; 012-467-661-652-474; 012-723-921-421-040; 013-039-574-512-524; 013-507-404-965-47X; 013-524-854-219-241; 013-895-193-312-854; 014-037-101-329-196; 014-239-919-508-428; 014-344-166-117-362; 014-638-168-086-508; 014-992-807-697-180; 015-315-842-154-120; 016-186-915-718-600; 016-811-357-339-489; 017-511-350-512-623; 021-498-285-976-739; 021-959-555-273-419; 022-480-877-678-293; 023-582-388-887-872; 024-063-292-435-128; 024-522-887-516-592; 024-755-208-280-811; 024-959-474-910-323; 026-807-100-421-71X; 027-434-527-905-948; 029-543-568-422-307; 030-019-625-644-868; 030-060-791-900-884; 032-651-266-266-501; 034-642-132-546-936; 036-554-323-177-750; 037-997-994-798-565; 038-065-575-854-848; 038-133-922-429-902; 038-738-429-499-773; 039-318-826-733-426; 040-627-653-003-146; 040-839-116-802-449; 042-135-214-875-569; 042-766-876-842-281; 043-526-501-935-928; 043-890-352-529-336; 045-723-528-250-369; 046-532-711-806-956; 046-862-859-991-483; 047-479-100-864-109; 047-550-977-643-221; 050-323-359-960-228; 051-647-739-244-271; 053-231-067-366-551; 054-397-662-452-784; 054-818-565-070-154; 055-069-593-800-960; 056-839-446-954-622; 058-442-203-980-874; 059-012-625-148-013; 060-726-715-566-235; 062-646-741-788-045; 064-886-980-553-791; 065-346-869-208-139; 065-516-419-444-125; 065-595-262-333-782; 066-803-591-864-760; 066-881-867-337-624; 068-819-389-881-152; 069-180-722-885-723; 069-919-785-718-255; 073-480-853-748-947; 073-500-390-409-070; 073-800-351-617-04X; 076-326-037-377-440; 077-603-866-630-81X; 079-997-052-392-784; 080-031-638-607-471; 082-177-091-359-99X; 084-050-628-354-393; 084-078-138-157-99X; 087-021-693-811-956; 087-159-453-343-083; 087-716-676-595-949; 090-445-409-198-515; 090-574-410-980-089; 090-619-723-616-583; 093-097-000-778-902; 099-315-542-220-920; 101-752-490-869-458; 102-218-287-007-824; 103-722-901-226-277; 104-005-422-335-032; 104-919-753-218-202; 107-356-524-436-217; 110-112-657-232-303; 113-468-801-170-394; 114-142-611-121-854; 115-795-297-982-545; 116-128-710-467-801; 116-189-493-462-420; 117-181-709-368-995; 117-543-680-676-331; 118-370-862-410-298; 118-967-278-262-339; 119-472-279-954-021; 121-537-747-109-301; 124-564-368-843-920; 124-991-491-584-852; 125-198-840-012-629; 126-959-576-059-304; 132-246-163-630-223; 132-282-484-040-054; 134-503-471-350-853; 136-141-774-411-905; 136-750-198-921-344; 139-063-282-265-903; 139-350-350-743-666; 140-098-528-501-220; 144-716-891-197-447; 145-521-297-490-305; 146-860-530-011-01X; 148-498-766-533-600; 148-803-945-071-42X; 149-290-619-169-363; 151-804-773-363-284; 152-890-061-051-776; 155-898-709-829-073; 160-171-099-524-697; 176-507-703-794-78X; 176-924-404-626-572; 178-839-991-198-416; 181-154-400-342-604; 189-044-361-957-879,189,false,, -010-083-375-661-155,Scientific review of climate science: A bibliometric analysis of trends,2024-06-27,2024,journal article,E3S Web of Conferences,22671242; 25550403,EDP Sciences,,Maria Goncharova; Elizaveta Sokolova,"This research analyses the metadata of 15550 climatology publications indexed in the OpenAlex data catalogue of the types ‘article’ (95%), ‘book’ (3%) and ‘book-chapter’ (2%). The research covers the period from 1851 to the present. Bibliometrix and VOSviewer software tools were used for data processing and analysis, and Scimago Graphica was used to visualise the results. As a result of the research, new data on the periods of authors' publication activity by subject, supported by the systematisation of the main scientific achievements and changes of those times, were obtained. The structure of access to publications in climatology and its impact on the attention of the scientific community, thematic diversity and the most relevant current research areas were also analysed.",542,,4008,04008,Climate science; Bibliometrics; Climate change; Regional science; Geography; Data science; Environmental science; Computer science; Library science; Geology; Oceanography,,,,,https://www.e3s-conferences.org/10.1051/e3sconf/202454204008/pdf,http://dx.doi.org/10.1051/e3sconf/202454204008,,10.1051/e3sconf/202454204008,,,0,015-498-593-536-316; 017-503-280-353-718; 020-750-501-347-722; 056-265-826-212-452; 074-029-201-612-091,1,true,cc-by,gold -010-325-403-369-098,Hypersensitivity Reaction to Metal: A Bibliometric Study.,2022-10-11,2022,journal article,SAGE open nursing,23779608,SAGE Publications,United States,Tassia Teles Santana de Macedo; Itana Lúcia Azevêdo de Jesus; Wilton Nascimento Figueredo; Dzifa Dordunoo,"Background: To delineate the scientific publications on metal hypersensitivity. Methods: Scopus database from 1946 to 2020, written in English, Spanish, or Portuguese. This is a bibliometric study, with a descriptive and quantitative approach. For data analysis, we used RStudio® and VOSviewer® and bibliometric packages-bibliometrix and biblioshiny. Results: Of the 804 articles retrieved, most of the publications come from European, Asian, and American countries, with Germany, Japan, and United States leading. Published articles and keywords refer to orthopedic, dermatological, and orthodontic specialties. Conclusion: Scientific production is scarce with slight oscillations in the studied period, authored predominantly by researchers in North America and Europe. Articles were mostly published in scientific journals in the fields of dermatology, dentistry, and orthopedics, which indicated the need for greater investments in the research development on the topic.",8,,23779608221132164,237796082211321,Scopus; Portuguese; Medicine; Bibliometrics; Library science; Web of science; Family medicine; MEDLINE; Political science; Pathology; Computer science; Philosophy; Linguistics; Meta-analysis; Law,adverse effects; allergy; bibliometric literature review; hypersensitivity; metals,,,Escola Bahiana de Mecina e Saúde Pública,https://dspace.library.uvic.ca/bitstream/1828/14749/1/Dordunoo_Dzifa_SAGEOpenNurs_2022.pdf http://hdl.handle.net/1828/14749,http://dx.doi.org/10.1177/23779608221132164,36245849,10.1177/23779608221132164,,PMC9558856,0,001-719-026-803-199; 003-822-109-075-586; 005-443-959-344-28X; 005-526-996-469-448; 007-551-023-268-049; 014-007-391-992-078; 025-628-439-913-676; 026-148-303-296-385; 027-656-666-041-40X; 038-186-496-856-133; 039-077-468-132-06X; 042-889-730-309-425; 045-897-550-696-711; 056-178-349-773-437; 063-338-398-963-37X; 071-002-707-690-91X; 071-463-469-373-59X; 076-267-539-268-407; 079-427-766-898-387; 080-158-792-215-319; 091-697-821-039-513; 093-666-631-360-630; 095-544-374-735-119; 109-055-063-590-687; 110-497-349-524-603; 119-557-426-467-219; 166-190-074-702-559,0,true,"CC BY, CC BY-NC",gold -010-390-603-478-660,Exploring research topics and trends in early childhood education using structural topic modeling,2024-10-01,2024,journal article,SN Social Sciences,26629283,Springer Science and Business Media LLC,,Michael Methlagl; Natascha J. Taslimi; Christian Rudloff; Jutta Majcen,"AbstractEarly childhood education plays a key role in fostering child development and preparing children for school and life. The aim of the present paper is to give an overview of research topics in early childhood education research based on the analysis of 39,926 scientific articles published between 2000 and 2021 and to explore research trends over time. Therefore, a structural topic modelling approach was used. The analyses show a strong increase in publication activity over the last years as well as the diversity of research topics, which provide important insights for achieving the UN Sustainable Development Goals in various areas (cultural diversity, design of inclusive learning environments, educational institutions, professional development issues, educational policy and reforms, etc.). Beside topics like cultural diversity, and inclusive learning environments more specific research topics, for example self-regulation, executive functions, numeracy, language development and physical activity have been increasingly addressed in publications over the years.",4,10,,,Psychology; Mathematics education; Data science; Computer science,,,,University of Applied Sciences Wiener Neustadt,,http://dx.doi.org/10.1007/s43545-024-00982-x,,10.1007/s43545-024-00982-x,,,0,001-150-518-337-733; 002-799-061-909-801; 003-554-382-116-811; 007-398-430-237-364; 008-274-139-069-264; 009-286-240-384-618; 009-875-062-074-988; 011-651-306-204-785; 013-507-404-965-47X; 014-847-486-068-138; 021-607-320-753-152; 025-220-627-825-105; 030-747-074-581-586; 033-502-125-795-300; 035-215-625-829-723; 037-888-139-840-918; 038-785-862-799-373; 039-052-887-520-701; 051-389-732-644-775; 051-720-046-820-65X; 055-650-666-387-097; 062-031-938-948-910; 069-001-992-207-133; 069-133-957-040-416; 074-689-637-760-304; 082-455-715-901-183; 084-894-458-306-857; 084-926-011-346-063; 087-318-486-595-960; 092-141-440-731-824; 095-954-592-894-523; 111-719-910-096-809; 149-397-683-301-496,0,true,cc-by,hybrid -010-408-116-295-536,Role of Artificial Intelligence in the crime prediction and pattern analysis studies published over the last decade: a scientometric analysis,2024-07-11,2024,journal article,Artificial Intelligence Review,15737462; 02692821,Springer Science and Business Media LLC,Netherlands,Manpreet Kaur; Munish Saini,"AbstractCrime is the intentional commission of an act usually suspected as socially detrimental and specifically defined, forbidden, and punishable under criminal law. Developing a society that is less susceptible to criminal acts makes crime prediction and pattern analysis (CPPA) a paramount topic for academic research interest. With the innovation in technology and rapid expansion of Artificial Intelligence (AI), the research in the field of CPPA has evolved radically to predict crime efficiently. While the number of publications is expanding substantially, we believe there is a dearth of thorough scientometric analysis for this topic. This work intends to analyze research conducted in the last decade using Scopus data and a scientometric technique, emphasizing citation trends and intriguing journals, nations, institutions, their collaborations, authors, and co-authorship networks in CPPA research. Furthermore, three field plots have been staged to visualize numerous associations between country, journal, keyword, and author. Besides, a comprehensive keyword analysis is carried out to visualize the CPPA research carried out with AI amalgamation. A total of five clusters have been identified depicting several AI methods used by the researchers in CPPA and the evolution of research trends over time from various perspectives.",57,8,,,Crime analysis; Scopus; Field (mathematics); Citation; Commission; Scientometrics; Computer science; Data science; Citation analysis; Criminology; Political science; Sociology; Library science; Law; MEDLINE; Mathematics; Pure mathematics,,,,,https://link.springer.com/content/pdf/10.1007/s10462-024-10823-1.pdf https://doi.org/10.1007/s10462-024-10823-1,http://dx.doi.org/10.1007/s10462-024-10823-1,,10.1007/s10462-024-10823-1,,,0,002-052-422-936-00X; 004-754-933-308-274; 005-253-259-920-023; 005-358-712-520-601; 006-235-651-110-540; 008-938-979-592-022; 011-176-116-774-795; 011-973-719-448-560; 013-507-404-965-47X; 015-440-921-647-313; 015-692-170-714-052; 016-020-089-856-613; 018-296-182-865-610; 020-550-523-238-950; 026-184-988-953-189; 029-154-918-059-95X; 030-551-495-502-968; 033-842-587-903-100; 046-132-955-608-232; 048-427-048-488-16X; 049-391-379-302-694; 050-690-902-463-026; 050-760-824-612-903; 051-848-847-730-534; 054-147-266-467-026; 054-661-571-983-942; 058-704-994-137-644; 064-395-019-057-658; 064-948-898-743-327; 065-362-672-862-428; 065-852-338-675-602; 069-195-065-087-220; 078-929-792-378-338; 081-057-186-376-642; 086-401-945-735-725; 089-447-087-797-622; 090-483-913-788-351; 092-149-700-153-263; 104-530-540-592-481; 105-725-090-305-524; 109-651-852-878-377; 116-741-893-608-309; 118-983-171-794-909; 122-773-893-356-993; 134-274-476-902-198; 148-004-098-947-855; 160-408-486-256-39X; 170-140-830-315-167; 182-005-396-425-26X; 193-882-095-846-144,5,true,cc-by,hybrid -010-491-208-243-717,Critical analysis of hot topics in diabetic nephropathy related experimental research: A bibliometric analysis from 2018 to 2024.,2025-01-04,2025,journal article,Journal of tissue viability,0965206x; 18764746,Elsevier BV,United Kingdom,Youduo Jia; Yunfei Gu; Lijun Wang; Nan Jiang; Xiumei Yu; Hu Tian,"Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a leading cause of end-stage renal disease worldwide. Understanding trends in experimental research on DN is crucial for advancing knowledge and clinical management.; This study aimed to explore current trends in DN related experimental research, utilizing CiteSpace, VOSviewer, and Bibliometrix to identify key contributors, influential countries, and noteworthy topics. The objective was to provide valuable insights for healthcare professionals and researchers in the field.; Relevant publications from the Web of Science Core Collection Science Citation Index Expanded were retrieved for the period between 2018 and 2024. CiteSpace, VOSviewer, and Bibliometrix were employed for data analysis, including identifying top authors, institutions, countries, keywords, co-cited authors, journals, references, and research trends.; A total of 1501 relevant articles were included in the study. DN related experimental research exhibited an upward trend, reaching its peak in 2023. Key contributors such as Kretzler Matthias, Li Ping, and Rossing Peter emerged. China, the United States and Japan have the most publications. Keyword analysis revealed ""activated protein kinase"" as the most central keyword, while ""diabetic nephropathy"" had the highest citation rate. Recent focus shifted towards keywords like ""Traditional Chinese Medicine"" and ""molecular docking.""; This bibliometric analysis provides insights into trends in experimental research on DN from 2018 to 2024. Notable contributors and influential countries were identified, emphasizing global collaboration. Key topics demonstrate diverse approaches and emerging trends, supporting informed decision-making and innovation in combatting DN and enhancing patient outcomes.; Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.",34,1,100854,100854,Medicine; Diabetic nephropathy; Nephropathy; Bibliometrics; Library science; Diabetes mellitus; Endocrinology; Computer science,Bibliometric analysis; Diabetic nephropathy; Experimental research; Hotspots,Diabetic Nephropathies/physiopathology; Bibliometrics; Humans; Biomedical Research/trends,,,,http://dx.doi.org/10.1016/j.jtv.2025.100854,39764975,10.1016/j.jtv.2025.100854,,,0,003-542-621-198-618; 003-837-951-150-121; 004-493-084-008-230; 010-938-039-632-049; 019-403-256-617-773; 022-009-194-831-338; 025-823-884-896-943; 032-234-212-903-088; 038-264-617-107-798; 042-452-383-285-622; 045-599-175-912-682; 053-410-914-248-171; 054-593-712-974-096; 061-877-295-914-153; 063-332-816-543-785; 072-936-894-769-994; 073-898-591-853-381; 076-824-313-721-474; 092-889-107-756-155; 109-642-299-631-621; 132-967-263-427-679; 141-937-815-692-665; 154-114-390-105-158,1,true,cc-by-nc-nd,hybrid -010-860-960-918-808,Trends of Research on Mindfulness: a Bibliometric Study of an Emerging Field,2023-03-31,2023,journal article,Trends in Psychology,23581883,Springer Science and Business Media LLC,,Gabriel Ferraz Ferreira; Marcelo Demarzo,,32,2,466,479,Mindfulness; Bibliometrics; Subject (documents); Web of science; Psychological intervention; Impact factor; Psychology; Library science; MEDLINE; Political science; Computer science; Clinical psychology; Psychiatry; Law,,,,Conselho Nacional de Desenvolvimento Científico e Tecnológico,,http://dx.doi.org/10.1007/s43076-023-00286-8,,10.1007/s43076-023-00286-8,,,0,001-554-877-975-914; 005-636-842-489-726; 007-858-416-878-928; 008-036-330-792-756; 009-657-323-525-068; 012-114-389-955-80X; 013-507-404-965-47X; 013-772-772-516-480; 016-727-531-256-215; 016-899-253-198-959; 019-008-132-364-604; 021-404-987-579-148; 023-927-221-065-800; 026-272-619-715-994; 034-768-039-318-254; 035-494-531-596-791; 037-565-187-791-907; 038-478-666-137-532; 040-580-575-623-36X; 045-881-693-065-531; 046-713-462-816-91X; 047-962-085-362-740; 053-104-475-700-596; 054-770-019-739-973; 071-878-836-294-733; 083-846-900-133-264; 088-660-703-547-659; 088-908-268-737-277; 099-650-256-973-997; 102-985-858-003-729; 104-869-835-316-030; 108-437-146-031-212; 127-645-778-235-147; 147-199-278-864-535; 151-066-640-236-837,6,false,, -010-883-674-235-936,Bibliometric analysis of digital library in Indonesia 2014-2024 using Biblioshiny Bibliometrix,2025-06-19,2025,journal article,Berkala Ilmu Perpustakaan dan Informasi,24770361; 16937740,Universitas Gadjah Mada,,Diaz Ilyasa; Yunus Winoto; Evi Nursanti Rukmana,"Introduction. This study understands the development of digital libraries in Indonesia in the 2014-2024 period using bibliometrics, along with the rapid internet penetration and the increasing number of digital libraries in Indonesia which have changed the way people access information.; Data Collection Methods. This is a quantitative approach with a bibliometric analysis based on the Scopus bibliographic dataset with 162 publications with a keyword filtering process.; Data Analysis. This is a bibliometric analysis using Biblioshiny Bibliometrix.; Results and Discussion. This study shows that despite fluctuations, digital library research in Indonesia has increased, especially in 2017 and 2021, reflecting growing awareness during the COVID-19 pandemic, with a focus on ""digital libraries"" and related topics like ""systematic literature review"", ""e-learning"" and ""library services"". These themes are supported by key researchers from Ganesha University of Education, Bina Nusantara University, and the University of Indonesia.; Conclusion. Digital library research in Indonesia continues to develop from year to year, still focusing on the topics of digital libraries, e-learning, and library services, with authors collaborating and developing new topics in this area. Suggestions for further research include thematic evolution analysis and references spectroscopy to better illustrate the development of this topic.",21,1,77,92,,,,,,,http://dx.doi.org/10.22146/bip.v21i1.16158,,10.22146/bip.v21i1.16158,,,0,,0,true,cc-by-sa,gold -011-044-486-722-509,"""Research exceptionalism"" in the COVID-19 pandemic: an analysis of scientific retractions in Scopus",2022-06-07,2022,journal article,Ethics & Behavior,10508422; 15327019,Informa UK Limited,United States,Priscila Rubbo; Caroline Lievore; Celso Biynkievycz Dos Santos; Claudia Tania Picinin; Luiz Alberto Pilatti; Bruno Pedroso,"This study aimed to outline the profile of retractions of scientific articles on COVID-19 published in journals indexed in the Scopus database between 2020 and 2021. To analyze the data, we used a bibliometric technique, with the Bibliometrix package in the R-Studio software, and descriptive statistics. Twenty-nine retractions were analyzed, and we found that the most common reasons for retraction were related to ethical issues and that 68.97% of authors have previously retracted articles. We concluded that there appears to have been a change in the publication policies of journals, which resulted in an increase in scientific retractions related to COVID-19 during the study period.",33,5,339,356,Scopus; Coronavirus disease 2019 (COVID-19); Pandemic; Descriptive statistics; Exceptionalism; 2019-20 coronavirus outbreak; Political science; MEDLINE; Statistics; Medicine; Law; Virology; Mathematics; Disease; Pathology; Politics; Outbreak; Infectious disease (medical specialty),,,,,,http://dx.doi.org/10.1080/10508422.2022.2080067,,10.1080/10508422.2022.2080067,,,0,000-661-165-122-830; 001-603-090-273-976; 002-895-760-133-651; 003-095-100-474-064; 003-419-687-703-53X; 005-420-327-194-517; 006-044-323-199-230; 006-390-519-990-325; 006-457-039-206-005; 006-457-411-091-209; 007-255-600-199-885; 007-605-480-415-455; 008-329-649-073-373; 009-806-913-742-800; 010-685-306-938-42X; 011-105-981-647-944; 011-357-585-641-840; 013-507-404-965-47X; 013-858-004-690-475; 014-012-301-004-539; 015-089-503-477-555; 016-976-085-079-657; 017-161-486-233-386; 018-365-793-781-156; 019-222-995-079-689; 020-809-650-616-643; 021-866-897-858-633; 022-039-146-650-580; 022-857-090-199-675; 024-823-049-331-504; 031-727-771-490-629; 031-808-580-156-243; 035-642-776-196-51X; 037-111-007-997-259; 038-252-873-184-508; 039-564-977-089-432; 041-247-629-944-319; 049-923-708-988-944; 053-773-190-531-328; 053-851-213-948-128; 059-417-467-014-073; 063-142-943-011-231; 064-609-629-793-258; 065-642-138-927-590; 065-789-336-024-508; 067-248-150-042-477; 068-723-333-054-821; 073-769-934-332-65X; 074-171-468-110-493; 079-210-905-331-173; 080-428-949-404-626; 082-262-875-863-250; 082-695-104-701-150; 085-043-558-780-258; 087-766-367-533-483; 088-141-082-462-155; 097-191-403-265-85X; 099-284-815-163-847; 101-683-606-832-029; 104-058-878-056-655; 107-968-285-384-022; 109-341-592-915-819; 112-301-628-691-880; 113-494-757-364-958; 117-985-439-380-778; 132-567-539-536-209,3,false,, -011-315-723-898-965,Research and partnership in studies of sugarcane using molecular markers: a scientometric approach,2019-02-25,2019,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Ivone de Bem Oliveira; Rhewter Nunes; Lucia Mattiello; Stela Barros-Ribeiro; Isabela Pavanelli de Souza; Alexandre Siqueira Guedes Coelho; Rosane G. Collevatti,,119,1,335,355,Publishing; Sociology of scientific knowledge; Geography; Data science; Science mapping; Time frame; International partnership; Research groups; Lack of knowledge; General partnership,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Instituto Nacional de Ciência e Tecnologia - Ecologia Evolução Conservação da Biodiversidade; Fundação de Amparo a Pesquisa do Estado de São Paulo; Fundação de Amparo a Pesquisa do Estado de São Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico,https://link.springer.com/article/10.1007/s11192-019-03047-6 https://bv.fapesp.br/pt/publicacao/164327/research-and-partnership-in-studies-of-sugarcane-using-molec/ https://doi.org/10.1007/s11192-019-03047-6 https://ideas.repec.org/a/spr/scient/v119y2019i1d10.1007_s11192-019-03047-6.html https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics119.html#OliveiraNMBSCC19,http://dx.doi.org/10.1007/s11192-019-03047-6,,10.1007/s11192-019-03047-6,2917087191,,0,000-748-759-128-932; 002-052-422-936-00X; 007-063-456-603-09X; 009-247-542-703-926; 013-507-404-965-47X; 016-305-117-891-280; 016-740-398-292-271; 017-345-869-815-558; 017-474-489-537-948; 018-209-256-175-834; 018-827-426-218-998; 019-352-425-375-748; 021-649-609-935-85X; 022-114-641-164-173; 023-392-642-125-295; 024-618-118-867-378; 024-873-254-982-002; 025-410-460-379-322; 026-353-164-231-313; 029-883-007-257-496; 031-034-456-107-341; 032-264-235-019-743; 032-543-115-914-489; 033-466-689-912-757; 035-874-511-846-241; 035-910-741-165-578; 039-278-594-176-670; 039-418-711-901-360; 039-979-576-935-006; 040-059-491-733-097; 040-853-776-155-399; 041-440-666-246-098; 043-461-489-768-199; 044-639-629-506-310; 046-390-028-500-134; 047-950-052-831-08X; 048-181-414-226-323; 050-837-027-596-202; 056-426-226-149-95X; 058-983-445-245-030; 062-474-936-710-928; 068-487-448-989-262; 069-585-539-568-135; 071-088-887-063-12X; 071-388-998-747-625; 071-651-994-549-395; 072-179-004-209-667; 077-652-050-910-393; 079-399-688-745-856; 079-834-240-285-525; 080-392-605-449-642; 081-393-843-662-909; 082-395-473-505-812; 085-758-097-657-386; 099-872-137-230-713; 101-752-490-869-458; 102-633-618-307-492; 114-300-984-750-689; 119-453-062-348-537; 129-632-604-277-582; 134-015-335-017-017; 137-441-003-026-727; 195-910-987-577-38X,11,false,, -011-398-350-028-671,Keyword occurrences and journal specialization,2023-09-03,2023,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Gabriele Sampagnaro,"AbstractSince the borders of disciplines change over time and vary across communities and geographies, they can be expressed at different levels of granularity, making it challenging to find a broad consensus about the measurement of interdisciplinarity. This study contributes to this debate by proposing a journal specialization index based on the level of repetitiveness of keywords appearing in their articles. Keywords represent one of the most essential items for filtering the vast amount of research available. If chosen correctly, they can help to identify the central concept of the paper and, consequently, to couple it with manuscripts related to the same field or subfield of research. Based on these universally recognized features of article keywords, the study proposes measuring the specialization of a journal by counting the number of times that a keyword is Queryrepeated in a journal on average (Sj). The basic assumption underlying the proposal of a journal specialization index is that the keywords may approximate the article’s topic and that the higher the number of papers in a journal based on a topic, the higher the level of specialization of that journal. The proposed specialization metric is not invulnerable to a set of limitations, among which the most relevant seems to be the lack of a standard practice regarding the number and consistency of keywords appearing in each article.",128,10,5629,5645,Computer science; Consistency (knowledge bases); Field (mathematics); Metric (unit); Set (abstract data type); Index (typography); Granularity; Information retrieval; Data science; Epistemology; Sociology; World Wide Web; Mathematics; Artificial intelligence; Philosophy; Operations management; Pure mathematics; Economics; Programming language; Operating system,,,,Università Parthenope di Napoli,https://link.springer.com/content/pdf/10.1007/s11192-023-04815-1.pdf https://doi.org/10.1007/s11192-023-04815-1,http://dx.doi.org/10.1007/s11192-023-04815-1,,10.1007/s11192-023-04815-1,,,0,001-505-316-389-789; 002-052-422-936-00X; 005-911-229-931-719; 013-507-404-965-47X; 022-923-089-953-979; 024-315-118-519-527; 029-725-111-315-779; 032-088-505-948-500; 033-656-568-358-38X; 037-326-531-131-863; 040-417-707-702-730; 047-364-369-116-795; 048-479-832-436-907; 052-068-260-447-069; 056-111-962-365-005; 059-396-850-813-265; 059-981-753-845-297; 060-915-127-259-848; 062-885-824-900-379; 064-788-023-780-053; 065-262-477-959-680; 069-150-296-944-200; 070-261-331-611-581; 075-901-685-548-051; 077-422-442-439-859; 079-047-687-535-17X; 079-278-714-415-834; 082-051-865-919-302; 083-214-425-339-435; 125-611-985-399-234; 141-200-607-894-303; 149-691-447-014-396; 149-822-010-034-439; 167-148-923-567-724; 172-535-268-985-532,10,true,cc-by,hybrid -011-887-829-972-928,Nostalgia in tourism: a bibliometric analysis and systematic review,2024-03-08,2024,preprint,,,Research Square Platform LLC,,Angie Lorena Salgado Moreno; Jorge Alexander Mora Forero,"Abstract; The main objective of this bibliometric review is to identify and analyze the development of the field of nostalgia tourism through a comprehensive analysis of the scientific literature. To this end, this article performs a bibliometric analysis in R Core Team 2022-Bibliometrix software, complemented by VOSviewer software and a systematic review of the Scopus and Science Direct database to provide information on the most researched topics, the most influential authors and publications, as well as the areas requiring further research. The findings and conclusions of this study make a valuable contribution to the nostalgia tourism literature by providing a relevant and comprehensive analysis of the current state. This analysis allows for a better understanding of the theoretical and conceptual framework of the articles published so far, which is important to consider in order to enrich the academic debate on nostalgia tourism and for future research.",,,,,Tourism; Regional science; Data science; Geography; Computer science; Archaeology,,,,,https://www.researchsquare.com/article/rs-4018205/latest.pdf https://doi.org/10.21203/rs.3.rs-4018205/v1,http://dx.doi.org/10.21203/rs.3.rs-4018205/v1,,10.21203/rs.3.rs-4018205/v1,,,0,002-697-153-322-699; 003-559-365-783-164; 004-761-850-477-115; 009-013-689-216-75X; 010-065-762-504-134; 010-289-488-549-868; 013-327-455-289-08X; 013-758-380-086-011; 015-314-807-462-254; 015-777-019-455-572; 015-928-824-208-588; 016-762-717-851-42X; 019-810-769-359-683; 021-307-231-397-083; 022-447-598-523-569; 028-442-155-623-881; 029-691-862-782-711; 030-910-726-665-281; 035-464-940-156-562; 036-304-504-423-752; 037-142-828-416-943; 038-068-749-448-22X; 041-834-275-880-587; 046-253-489-711-216; 048-249-891-327-029; 048-510-542-441-268; 053-778-283-077-104; 059-814-927-527-398; 060-782-139-563-680; 061-538-402-818-954; 062-567-033-771-204; 064-924-179-344-817; 065-244-730-579-798; 073-775-823-470-313; 076-952-835-453-16X; 085-155-363-611-063; 087-566-368-716-322; 087-799-422-083-739; 092-872-645-323-129; 096-472-527-387-204; 098-065-323-590-029; 104-180-503-111-346; 106-933-106-703-352; 111-393-931-417-125; 114-241-056-902-910; 114-447-625-031-398; 119-428-839-825-159; 119-948-724-206-517; 121-267-837-698-19X; 123-247-143-038-060; 128-968-695-066-168; 131-442-851-379-951; 133-347-966-726-56X; 133-587-274-663-150; 133-597-811-155-338; 145-754-191-280-905; 147-563-986-172-298; 159-201-092-684-486; 166-512-612-773-581; 172-149-619-340-766; 183-184-340-798-385,0,true,cc-by,green -011-952-301-392-560,Bibliometric Analysis of MOOC using Bibliometrix Package of R,2020-12-26,2020,conference proceedings article,2020 IEEE International Women in Engineering (WIE) Conference on Electrical and Computer Engineering (WIECON-ECE),,IEEE,,Ramneet Ramneet; Deepali Gupta; Mani Madhukar,"As a growing academic approach, MOOCs have gained widespread attention through academic courses. There are many MOOC platforms available like Udemy, Udacity, Coursera, Swayam, Khan Academy and EdX. All these platforms provide free as well as paid courses. These types of certifications help in boosting the career of the learners. A strong recommendation system is the need of the day for these types of platforms that will guide learners in selecting the appropriate course according to their levels. In this paper, 1511 journal articles have been selected through the Scopus database from 2012 to 2020. This study uses a bibliometric analysis method to visualize the knowledge network analysis with the help of the Biblioshiny tool of R software.",,,157,161,World Wide Web; Bibliometrics; Software; R software; Bibliometric analysis; Computer science; Certification; Recommender system; Scopus; Knowledge engineering,,,,,http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=9397952 http://xplorestaging.ieee.org/ielx7/9397876/9397924/09397952.pdf?arnumber=9397952,http://dx.doi.org/10.1109/wiecon-ece52138.2020.9397952,,10.1109/wiecon-ece52138.2020.9397952,3155558282,,0,001-023-795-793-508; 002-083-405-735-54X; 027-824-108-325-571; 038-460-125-283-793; 040-523-247-756-656; 041-783-314-562-622; 047-224-294-624-001; 048-540-591-432-023; 058-696-656-707-803; 061-900-019-279-336; 090-963-073-302-429; 091-274-257-334-372; 106-936-032-417-823; 110-901-237-001-586; 124-925-048-128-152; 130-429-584-008-300,5,false,, -012-198-917-177-919,A Ótica Bibliométrica,2025-02-23,2025,journal article,Brazilian Journal of Information Science: research trends,19811640,Faculdade de Filosofia e Ciências,,Andréa Fraga Dias Campos; Marlusa de Sevilha Gosling,"In constant transformation and evolution, the formation of new markets results from continuous actions. Bibliometric analysis can contribute to the knowledge of the field of scientific study of a topic or research area. In this sense, the objective of this study is to explore the existing literature on market construction, identifying how different authors structure and analyze different aspects of this process. To this end, the bibliometric method was adopted through the Bibliometrix package in the R software and bibliographic collections exported from the Scopus and Web of Science databases. The bibliometric analysis resulted in 121 documents published in the period from 1968 to 2024. Although the scientific production found on market construction was small, with peaks of growth and declines, it was demonstrated that there was an increase in publications over the years. The most frequent terms were highlighted, as well as identifying that the conceptual structure is composed of niche themes and basic and transversal themes.",19,,e025007,e025007,Political science,,,,,,http://dx.doi.org/10.36311/1981-1640.2025.v19.e025007,,10.36311/1981-1640.2025.v19.e025007,,,0,,1,true,cc-by-sa,gold -012-843-588-783-959,Mapping Altmetrics: A Bibliometric Analysis Using Scopus (2012-2024),2024-06-17,2024,journal article,Journal of Science and Knowledge Horizons,28001273; 28308379,Amar Telidji University of Laghouat,,Samira Guechairi,"This study conducts a comprehensive bibliometric analysis of the altmetrics landscape from 2012 to 2024, aiming to explore key trends, influential contributors, and thematic concentrations in scholarly discourse. The Bibliometrix package in R made it easy to conduct a bibliometric study on altmetrics using data extracted from Scopus. This allowed for an in-depth examination of publication trends, influential authors, and thematic concentrations. VOSviewer was used to visualize bibliometric data, which gave information about co-authorship networks and thematic clustering in the altmetrics literature. The United States emerged as the foremost contributor in terms of publication frequency. Key words such as ""bibliometrics,"" ""social media,"" and ""journal impact factor"" were identified as central themes in the altmetrics discourse, reflecting the multidimensional nature of scholarly evaluation in the digital age",4,1,172,192,Altmetrics; Scopus; Bibliometrics; Information retrieval; Geography; Data science; Computer science; Library science; MEDLINE; Political science; Law,,,,,,http://dx.doi.org/10.34118/jskp.v4i01.3859,,10.34118/jskp.v4i01.3859,,,0,,0,false,, -012-920-391-603-746,Global characteristics and trends of researches on watermelon: Based on bibliometric and visualized analysis.,2024-02-21,2024,journal article,Heliyon,24058440,Elsevier BV,Netherlands,Yu-Ping Zheng,"Watermelon is an important horticultural plant. A bibliometric analysis of the watermelon literature was carried out in order to analyze the research state, hotspots, and trends, as well as to highlight the overall watermelon research development from a holistic viewpoint. The summary of watermelon research is given via metrological analysis based on a set of indices using a newly built Bibliometrix R-package tool. This study gathered 6,632 documents indexed in the Core Collection of Web of Science (WoS) in the domain of watermelon from 1992 to 2022 using bibliometrix. The results indicated that the number of published articles showed an apparently upward trend. The United States was in the first place, with Plant Disease being the most productive journal. Levi A from the United States Department of Agriculture-Agricultural Research Service is the most prolific author, and Levi A is the most cited; The most frequently used keywords by authors are ""growth"", ""resistance"", ""identification"", ""yield"", ""quality"" ""plants"", ""watermelon stomach"" and ""expression""; The most talked-about issues in this subject are resistance, yield, and quality, which highlight the crucial research areas. To effectively comprehend the turning moments for future research, it is useful to monitor the hotspots and frontiers of watermelon studies. The results highlight the future paths for study in the field of watermelon and provide useful information for researchers interested in the topic.",10,5,e26824,e26824,Identification (biology); Agriculture; Web of science; Subject (documents); Data science; Quality (philosophy); Library science; Social science; Computer science; Geography; Political science; Sociology; Biology; MEDLINE; Philosophy; Epistemology; Botany; Archaeology; Law,Bibliometric analysis; Bibliometrix; Visualized analysis; Watermelon,,,,https://www.cell.com/article/S240584402402855X/pdf https://doi.org/10.1016/j.heliyon.2024.e26824,http://dx.doi.org/10.1016/j.heliyon.2024.e26824,38434322,10.1016/j.heliyon.2024.e26824,,PMC10907791,0,000-821-495-705-799; 001-091-957-562-281; 001-199-420-523-383; 002-467-994-337-592; 005-984-673-781-099; 009-545-864-226-187; 010-065-762-504-134; 010-495-710-613-419; 010-978-341-652-186; 011-767-233-119-647; 016-061-941-322-926; 019-565-928-239-413; 021-474-189-137-63X; 024-349-499-812-094; 025-665-424-027-658; 027-414-120-122-097; 029-964-032-323-373; 030-493-386-400-468; 032-124-356-099-466; 032-830-692-784-727; 033-127-677-566-360; 034-616-423-073-594; 045-425-357-777-67X; 045-997-661-794-283; 046-453-204-339-251; 046-992-864-415-70X; 052-557-731-366-618; 056-881-565-360-981; 062-491-960-450-796; 063-587-802-691-781; 064-264-695-662-36X; 079-679-789-158-219; 086-458-426-497-478; 100-986-383-973-044; 112-185-127-817-398; 117-663-570-987-16X; 121-652-742-486-910; 129-693-435-524-923; 142-055-777-535-117; 146-208-436-691-12X; 154-535-414-802-675; 159-105-594-520-262; 160-911-729-750-48X; 184-559-958-176-814; 192-323-382-937-148; 194-739-135-241-524,3,true,"CC BY, CC BY-NC-ND",gold -012-984-705-325-316,SAĞLIK BAKIM HİZMETLERİ ALANINDA YAPILAN INOVASYON KONULU MAKALELERİN BİLİM HARİTALAMA TEKNİKLERİYLE ANALİZİ,2022-07-01,2022,journal article,Elektronik Sosyal Bilimler Dergisi,13040278,Electronic Journal of Social Sciences,,Serdal Keçeli,"Öz:; Bu çalışmanın temel amacı sağlık bakım hizmetleri alanında yapılan inovasyon konulu makalelerin bilim haritalama teknikleri ile incelemektir. R tabanlı Bibliometrix ve VOSviwer yazılımları kullanılarak, en etkili yazar, ülke, kurum ve dergiler tespit edilmiştir. Bir arama staretisi ile 1975-2019 yılları arasındaki Web of Science makaleleri Core koleksiyondan indirilmiş ve Bibliyometrix ve VOSviwer yazılımları ile analiz edilmiştir. Sadece bir yazılım ile inceleme yapılmamasının en büyük sebebi ise her bir yazılımın öne çıktığı ve diğer yazılımlarda olmayan karşılaştırmalı üstünlüktür. İnovasyon konusunda en çok makale yayınlayan ülkeler arasında ABD, Kanada, İngiltere, Hollanda ve Fransanın yer aldığı ve Health Policy dergisinin bu konuda en fazla makale yayınlayan dergi olduğu yapılan analizler sonucunda ortaya çıkmıştır. Ayrıca h ve g indeksleri en yüksek yazar Weiner olarak tespit edilmiştir. Teknolojik gelişmelerin etkisi ile ortaya çıkan sağlık inovasyonundaki gelişmeler, hasta yaşam beklentisini ve yaşam kalitesini başarılı bir şekilde arttırmaktadır. Sağlık bakım hizmeleri alanında sunulan bakım, tedavi ve teşhis birçok konuda verimliliği arttırdığından maliyetlerin azalmasına ve insan hatalarını minimize etmeye yardımcı olmaktadır. Yapılan bu çalışma ile klinisyenler, sağlık hizmeti sağlayıcıları-tedarikçiler, araştırmacılar, politika yapıcılar, karar vericiler ve hastalar ortaya çıkan verilerin analizinden elde edilen yeni bilgiler ışığında yeni fırsatlar elde edebileceklerdir.; Anahtar Kelimeler: Sağlık Bakım Hizmetleri, İnovasyon, Bibliyometrik Analiz.; Abstract:; The main purpose of this study is to examine the innovation articles in the field of health care services with science mapping techniques. Using R-based Bibliometrix and VOSviwer software, the most influential authors, countries, institutions and journals were determined. Web of Science articles between 1975 and 2019 were downloaded from the Core collection with a search engine and analyzed with Bibliometrix and VOSviwer software. The biggest reason for not reviewing with only one software is the comparative advantage in which each software stands out and is not available in other software. It has emerged as a result of the analysis that the USA, Canada, England, Netherlands and France are among the countries that publish the most articles on innovation, and that the Health Policy journal is the journal that publishes the most articles on this subject. In addition, the h and g indexes were determined as the highest author Weiner. Developments in health innovation, which emerged with the effect of technological developments, successfully increase patient life expectancy and quality of life. Care provided in the field of health care services; As it increases efficiency in many areas such as treatment and diagnosis, it helps to reduce costs and minimize human errors. With this study, clinicians, healthcare providers-suppliers, researchers, policy makers, decision makers and patients will be able to gain new opportunities in the light of new information obtained from the analysis of the emerging data.; Keywords: Health Care Services, Innovation, Bibliometric Analysis.",21,83,1201,1224,Political science; Physics; Humanities; Gynecology; Philosophy; Medicine,,,,,https://dergipark.org.tr/tr/download/article-file/1967319 https://doi.org/10.17755/esosder.993612,http://dx.doi.org/10.17755/esosder.993612,,10.17755/esosder.993612,,,0,013-507-404-965-47X; 051-647-739-244-271,0,true,cc-by-nc,hybrid -013-122-852-973-601,"Innovación Social: Definiciones, Métricas, Temáticas clave, Agentes y Enfoques de impacto",2023-10-01,2023,journal article,UCJC Business and Society Review (formerly known as Universia Business Review),26593270,Pontificia Universidad Catolica de Chile,,Diego Rolando Minga- López; David Flores Ruiz,"This article analyses the trends in Social Innovation research published in the Social Science Citation Index (SSCI) of the Web of Science. It identifies its metrics, definitions, characteristics, agents and approaches, carrying out a bibliometric research with the software ""Bibliometrix"", as well as a bibliographic review of the 50 most cited articles. It is concluded that there is a multitude of definitions of social innovation with the common denominator being the implementation of new ideas and collaborative forms of relationship between different socio-economic agents to tackle complex social problems. Public entities are present in a significant number of articles, with concepts such as governance and co-creation emerging. However, a significant part of this research is addressed under a micro approach, which is considered necessary to increase the social impact and the transition to higher levels, meso and macro, which accommodate a greater number of agents, among which private entities stand out.",20,78,,,,,,,,,http://dx.doi.org/10.3232/ubr.2023.v20.n3.08,,10.3232/ubr.2023.v20.n3.08,,,0,,0,true,cc-by-nc,gold -013-133-563-595-193,The development and future frontiers of global ecological restoration projects in the twenty-first century: a systematic review based on scientometrics.,2023-02-03,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Xue Jiang; Yitao Sun; Yanping Qu; Houyuan Zeng; Jingtian Yang; Kaiyou Zhang; Lei Liu,,30,12,32230,32245,Mainstream; Bibliometrics; Restoration ecology; Scientometrics; China; Environmental resource management; Environmental restoration; Ecology; Environmental planning; Political science; Geography; Sociology; Social science; Computer science; Library science; Environmental science; Biology; Law,Bibliometrics analysis; Ecological project; Ecological restoration; Frontiers; Scientometrics; The twenty-first century,"Humans; Publications; Bibliometrics; Databases, Factual; China",,Sichuan Provincial Science and Technology Department Project (2021YFN0113); Scientific Research Project of Mianyang Normal University (QD2022A02),,http://dx.doi.org/10.1007/s11356-023-25615-3,36735127,10.1007/s11356-023-25615-3,,,0,001-976-179-016-388; 004-462-491-267-924; 004-601-990-237-364; 006-214-466-852-427; 007-325-205-347-420; 009-649-615-894-041; 012-153-382-143-915; 014-509-326-070-608; 015-241-022-477-216; 016-372-885-553-33X; 016-849-528-968-823; 017-452-141-087-010; 018-536-823-908-87X; 018-715-304-506-450; 020-454-065-228-885; 021-035-884-694-871; 021-657-427-980-502; 024-728-072-099-496; 025-715-327-178-756; 026-795-937-488-283; 028-262-673-689-700; 031-692-494-316-966; 031-981-533-350-35X; 034-034-664-766-818; 034-592-929-996-624; 034-734-891-019-908; 036-656-168-693-890; 039-114-324-898-429; 040-784-855-109-386; 040-921-088-193-342; 041-441-909-209-924; 042-218-907-976-315; 045-422-273-148-899; 047-697-612-213-997; 052-053-712-046-724; 052-085-029-279-108; 054-302-165-059-776; 054-515-112-890-573; 056-511-223-277-530; 056-692-403-401-91X; 060-267-404-979-542; 060-840-881-199-193; 062-734-887-378-014; 064-400-499-357-900; 067-601-465-004-912; 068-046-743-389-653; 071-845-322-337-774; 074-797-050-077-176; 075-083-201-211-347; 076-027-132-297-254; 078-826-484-834-571; 079-129-707-831-646; 080-778-223-211-876; 083-635-076-898-305; 085-619-436-252-19X; 085-721-930-992-83X; 093-535-016-214-762; 094-765-036-240-693; 095-058-889-606-689; 095-168-910-715-212; 098-220-215-603-838; 098-377-939-800-955; 100-896-610-043-148; 103-838-934-589-896; 104-305-733-077-223; 104-695-678-248-611; 106-525-691-012-567; 106-579-437-909-284; 108-759-894-055-780; 111-893-209-963-613; 114-214-364-017-83X; 114-945-058-697-282; 114-994-850-577-779; 120-250-288-382-725; 121-605-106-400-459; 125-581-942-315-104; 129-899-023-125-76X; 138-865-125-646-241; 139-080-813-380-033; 140-857-528-803-40X; 144-832-752-739-697; 149-655-194-061-654; 155-162-081-647-351; 156-735-305-310-777; 158-380-020-198-77X; 160-111-668-268-204; 168-965-952-701-781; 176-974-522-861-51X,14,false,, -013-151-208-188-007,Environmental Literacy Research: Global Scientometric Mapping of Five Decades,2021-12-31,2021,journal article,Current World Environment,23208031; 09734929,Enviro Research Publishers,,Vijay Kumar R; Thamizhiniyan K Thamizhiniyan K; Naseema S. Naseema S.,"To date, there is no scientometric study conducted on Environmental Literacy (EL) literature. Hence, this paper aims to bridge this gap.We aimed fora holistic scientometric analysis of scientific literature available on EL, whichresulted in finding global research trends in EL research. We operatedthe following scientometric tools: VOSviewer and Bibliometrix R Package-Biblioshiny for complete science mapping analysis of the collected bibliographic data retrieved from Scopus database. We analysed the Scopus scientific research outcomes during the last 50 years. The outcome included438 total documents published and among them 354 were articles and 84 were conference papers published by1112 authors from 50 countries. The findings of this study arevital for policy makers, researchers and other working in environmental education and literacy development to understand the potential gaps and strength in the current EL research in Scopus literature.",16,3,963,973,Scopus; Literacy; Scientometrics; Information literacy; Bibliometrics; Library science; Geography; Political science; Computer science; MEDLINE; Law,,,,,https://www.cwejournal.org/pdf/vol16no3/CWE_Vol16_No3_p_963-973.pdf https://doi.org/10.12944/cwe.16.3.26,http://dx.doi.org/10.12944/cwe.16.3.26,,10.12944/cwe.16.3.26,,,0,008-254-722-796-962; 009-474-471-349-703; 018-909-893-651-60X; 021-625-999-393-825; 025-302-119-966-613; 028-728-563-956-910; 030-866-793-053-335; 032-645-642-391-736; 032-984-727-691-996; 033-755-041-647-285; 038-544-612-700-636; 052-447-611-357-111; 065-710-759-342-87X; 077-366-148-356-063; 079-784-793-837-462; 091-641-192-223-031; 094-344-138-200-136; 113-306-900-003-995; 120-081-387-502-783; 124-337-876-880-138; 146-181-667-519-346,2,true,cc-by,gold -013-425-790-326-668,A bibliometric analysis of HIV-1 drug-resistant minority variants from 1999 to 2024.,2025-04-10,2025,journal article,AIDS research and therapy,17426405,Springer Science and Business Media LLC,United Kingdom,Chang Yan; Fengting Yu; Mengying Li; Xiaojie Yang; Rui Sun; Xuelei Liang; Xiaojie Lao; Hanxi Zhang; Wenhao Lv; Ying Hu; Yuan Lai; Yi Ding; Fujie Zhang,"The rapid initiation of antiretroviral therapy has become an international trend, necessitating lifelong medication for all HIV patients. Sanger sequencing, as the gold standard for clinically detecting HIV drug resistance, often fails to detect mutations comprising less than 20% of the total viral population. With the advancement of detection technologies, HIV-1 drug-resistant minority variants have garnered increasing attention. Few studies have analyzed the hotspots and trends in this field, which bibliometrics can effectively address.; Publications related to HIV-1 DRMinVs from 1999 to 2024 were searched on the Web of Science Core Collection database. Visual knowledge maps and bibliometric analyses were generated using VOSviewer and Bibliometrix.; In total, 289 publications concerning HIV-1 drug-resistant minority variants were identified from 1999 to 2024, demonstrating a steady increase in publication output over the years. Although developed countries, led by the United States, are the main contributors, 9.57% and 2.48% of the research from the top five publishing countries focus on populations in Africa and other developing countries, respectively. Most contributing institutions are universities and public health organizations, with the University of Washington having the highest publication output. The Journal of Antimicrobial Chemotherapy holds the highest prominence among journals in this domain. The main hotspots include ""drug classes,"" ""drug resistance surveillance,"" ""mother-to-child transmission,"" ""treatment outcomes,"" and ""targets of HIV-1 drug resistance testing,"" And we found several noteworthy shifts in research trends in HIV-1 drug-resistant minority variants studies, including changes in drug resistance testing technologies, the primary study population, and drug classes.; This is the first bibliometric analysis of publications related to HIV-1 DRMinVs from 1999 to 2024. We analyzed the key research contributions across countries, institutions and journals. Based on keyword co-occurrence and cluster analysis, we identified several noteworthy shifts in research trends in HIV-1 DRMinVs studies, including changes in drug resistance testing technologies, the primary study population, and drug classes.; © 2025. The Author(s).",22,1,47,,Medicine; Human immunodeficiency virus (HIV); Drug; Pharmacology; Traditional medicine; Virology,Bibliometrics; Drug-resistant minority variants; HIV-1; Hotspots,"HIV-1/drug effects; Bibliometrics; Humans; Drug Resistance, Viral/genetics; HIV Infections/drug therapy; Anti-HIV Agents/therapeutic use",Anti-HIV Agents,"Medical Talent Program for High-throughput Sequencing Technology in Infectious Diseases, China (MTP2022B020); R&D Program of the Beijing Municipal Education Commission, China (KM202210025004)",,http://dx.doi.org/10.1186/s12981-025-00739-3,40211381,10.1186/s12981-025-00739-3,,PMC11984210,0,000-288-554-922-45X; 000-354-385-645-502; 003-628-400-210-369; 007-641-899-286-742; 008-287-968-398-201; 009-800-941-278-868; 010-827-918-898-984; 012-229-628-960-180; 012-585-537-011-888; 013-507-404-965-47X; 014-028-950-826-125; 016-384-264-789-743; 017-751-207-810-671; 018-966-021-377-173; 020-569-185-740-517; 020-585-014-969-587; 021-461-450-087-689; 022-172-474-723-489; 025-630-668-478-770; 027-952-501-164-07X; 029-957-710-257-091; 031-620-191-716-265; 033-571-130-265-805; 034-386-493-062-603; 035-741-940-247-571; 039-157-451-221-605; 044-344-996-100-269; 047-220-329-339-457; 049-071-165-174-911; 052-439-185-776-187; 053-025-620-854-167; 053-082-905-492-535; 054-914-245-959-472; 055-840-097-182-426; 056-106-301-167-283; 056-789-727-153-773; 058-665-312-881-769; 059-337-043-030-571; 060-175-770-287-214; 062-831-413-754-369; 064-568-863-621-480; 064-950-408-581-736; 067-279-734-601-895; 068-552-678-048-028; 068-598-456-915-791; 071-818-803-513-819; 071-903-992-975-428; 073-502-648-073-535; 074-837-856-257-313; 078-737-553-041-344; 086-510-357-089-758; 086-678-735-561-634; 086-845-288-063-89X; 098-703-087-645-828; 099-399-162-654-322; 100-023-864-921-876; 100-103-201-235-437; 107-349-972-902-845; 112-208-990-586-024; 122-741-659-105-065; 130-302-440-928-441; 140-886-790-523-684; 145-351-993-692-833; 190-277-237-534-214,0,true,"CC BY, CC0",gold -013-507-404-965-47X,bibliometrix: An R-tool for comprehensive science mapping analysis,,2017,journal article,Journal of Informetrics,17511577,Elsevier BV,Netherlands,Massimo Aria; Corrado Cuccurullo,,11,4,959,975,Workflow; Bibliometrics; Data science; Bibliographic coupling; Co-citation; Software; R package; Science mapping; Computer science; Data flow diagram,,,,,https://EconPapers.repec.org/RePEc:eee:infome:v:11:y:2017:i:4:p:959-975 https://www.sciencedirect.com/science/article/abs/pii/S1751157717300500 https://doi.org/10.1016/j.joi.2017.08.007 https://www.iris.unina.it/handle/11588/683229 https://dblp.uni-trier.de/db/journals/joi/joi11.html#AriaC17 https://ideas.repec.org/a/eee/infome/v11y2017i4p959-975.html https://core.ac.uk/display/90979707 http://www.sciencedirect.com/science/article/abs/pii/S1751157717300500,http://dx.doi.org/10.1016/j.joi.2017.08.007,,10.1016/j.joi.2017.08.007,2755950973,,0,002-052-422-936-00X; 003-110-646-998-807; 004-663-421-235-506; 004-819-527-814-707; 005-688-363-332-013; 006-136-698-460-480; 006-461-237-333-939; 011-364-541-838-073; 012-322-802-314-94X; 013-524-854-219-241; 014-160-993-968-017; 015-774-079-830-633; 017-146-468-093-265; 017-349-318-774-487; 017-750-600-412-958; 023-927-221-065-800; 027-434-527-905-948; 028-037-650-718-395; 028-990-820-695-461; 030-671-248-846-321; 031-100-721-212-904; 032-858-825-665-444; 033-366-383-059-644; 035-123-099-408-882; 037-036-602-845-527; 037-483-252-551-928; 037-815-640-424-494; 042-516-200-963-479; 042-719-509-861-999; 045-319-398-508-266; 046-267-534-126-612; 046-457-900-689-069; 047-134-478-431-993; 049-978-563-341-311; 050-664-965-270-417; 051-865-643-777-765; 052-752-463-682-385; 054-540-913-080-41X; 054-818-565-070-154; 055-069-593-800-960; 058-814-931-176-272; 060-110-039-971-60X; 062-105-483-525-979; 065-516-419-444-125; 072-610-779-757-007; 079-884-499-916-715; 083-311-225-108-952; 101-752-490-869-458; 102-985-858-003-729; 116-560-190-874-907; 120-974-286-046-262; 123-202-581-406-928; 126-594-535-567-290; 130-348-276-035-425; 138-561-175-358-392; 140-679-184-307-082; 141-260-354-359-613; 142-608-256-821-705; 144-467-655-240-998; 150-325-162-873-23X; 154-958-212-177-335; 159-306-125-917-84X; 184-621-092-779-722,8232,false,, -013-721-490-959-777,Crisis Management: A Bibliometric Analysis,2023-06-01,2023,journal article,The Journal of Muamalat and Islamic Finance Research,29485266; 1823075x; 01265954,Universiti Sains Islam Malaysia,,Syadiyah Abdul Shukor; Norasikin Salikin; Ummi Salwa Ahmad Bustamam; Intan Fatimah Anwar; Siti Nurulhuda Nordin,"This study aims to analyse research on crisis management using a bibliometric review of 1569 articles collected from the Scopus database for the period between 1968 and 2022. Using Bibliometrix package in RStudio and Biblioshiny web apps, the current study analysed the annual publication trends, most active source titles, corresponding authors’ countries, most productive affiliations and examined citations pattern of the publication on crisis management.  This study also discusses the themes based on occurrences and terms of the keywords of the documents. The number of publications on crisis management followed the major crisis of the world. Since COVID-19 has a global impact, the number of publications has increased during the last three years. This study reviewed publications related to crisis management over the past five decades.  Accordingly, it can aid interested researchers in gaining a more in-depth understanding of crisis management.",,,64,78,Scopus; Crisis management; Web of science; Bibliometrics; Political science; Library science; Coronavirus disease 2019 (COVID-19); Computer science; MEDLINE; Medicine; Disease; Pathology; Infectious disease (medical specialty); Law,,,,,https://jmifr.usim.edu.my/index.php/jmifr/article/download/500/338 https://doi.org/10.33102/jmifr.500,http://dx.doi.org/10.33102/jmifr.500,,10.33102/jmifr.500,,,0,,2,true,cc-by,hybrid -013-790-328-595-177,Identifying the dissension in management and business research in Latin America and the Caribbean via co-word analysis,2022-01-05,2022,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Julián D. Cortés,,127,12,7111,7125,Latin Americans; Word (group theory); Political science; Regional science; History; Business; Linguistics; Sociology; Philosophy; Law,,,,,,http://dx.doi.org/10.1007/s11192-021-04259-5,,10.1007/s11192-021-04259-5,,,0,004-682-225-354-448; 004-819-527-814-707; 004-877-171-081-463; 005-394-809-940-272; 009-498-363-490-044; 010-620-785-811-153; 013-465-265-801-156; 013-507-404-965-47X; 014-473-299-963-416; 015-337-174-514-633; 015-692-170-714-052; 015-855-331-086-733; 017-750-600-412-958; 020-358-106-039-141; 028-990-820-695-461; 030-171-342-777-501; 030-482-625-417-029; 035-785-419-655-19X; 036-558-461-908-580; 037-545-415-239-228; 043-704-752-331-108; 044-808-566-509-681; 045-422-273-148-899; 052-990-583-105-500; 053-598-695-896-482; 057-686-710-128-621; 064-112-115-116-272; 065-650-789-828-633; 076-279-189-469-37X; 079-033-956-272-201; 083-202-108-164-16X; 086-341-446-522-651; 095-508-825-403-271; 095-799-968-131-675; 097-409-342-918-27X; 103-328-951-413-745; 121-303-482-318-359; 122-415-544-444-960; 127-077-879-493-863; 160-638-696-381-555; 182-347-456-782-286,7,false,, -013-929-548-521-958,A review of Reverse Innovation: From bibliometric analysis to a conceptual framework and future research directions,,2020,,,,,,B.R. Tijhof,"This study reviews Reverse Innovation (RI) literature by analysing the conceptual, intellectual and social structure of the field. Furthermore, it proposes a comprehensive view of the structural associations amongst RI influencing factors, drivers, antecedents and practices. Bibliometrix R-package and VOSViewer software were used to conduct a bibliometric meta-analysis on 208 articles, obtained from ISI Web of Science and Scopus databases. Influential journals, institutions, scholars and trending articles in RI research were revealed. Concept co-occurrence identified three main sub-fields (a) Conceptual development of RI, (b) Sustainable Dimension of RI, (c) RI for healthcare. Through content analysis of these sub-fields, conceptual conflicts were identified and solved. Based on this content analysis a conceptual framework was proposed which has structured influencing factors and relations to the RI process.",,,,,Conceptual framework; Sociology; Content analysis; Structure (mathematical logic); Reverse innovation; Dimension (data warehouse); Field (computer science); Process (engineering); Knowledge management; Scopus,,,,,https://repository.tudelft.nl/islandora/object/uuid%3Abbc1f51a-9406-49c5-a235-7eac90270bb8 https://repository.tudelft.nl/islandora/object/uuid%3Abbc1f51a-9406-49c5-a235-7eac90270bb8/datastream/OBJ/download,https://repository.tudelft.nl/islandora/object/uuid%3Abbc1f51a-9406-49c5-a235-7eac90270bb8,,,3170828377,,0,,0,false,, -014-026-651-199-214,Evolución del estudio sobre el efecto de la crianza en las conductas prosociales en la infancia y la adolescencia: una revisión sistemática,2021-05-04,2021,journal article,Actualidades en Psicología,22153535; 02586444,Universidad de Costa Rica,,Anyerson Stiths Gómez Tabares; Maria Cristina Correa Duque; Jorge Hernán González Cortés,"Objective. To conduct a systematic review of the evolution and documented empirical evidence on the effect of parenting on the development of prosocial behaviors in childhood and adolescence. Method. A bibliometric and citation network analysis was performed using bibliometrix and Tree of Science (ToS) tools. The bibliographic search was carried out in Scopus and Web of Science. Results. Scientific production between 2000 and 2020 increased between 10% and 13%. The studies were segmented into classic, structural, and recent. Classical studies analyzed the direct effect of parental discipline on prosocialbehaviors. The structural ones analyzed the emotional factors that mediate the association between parenting and prosocial behaviors. The recent ones provide additional evidence on the mediating role of empathy and the incorporation of a crosscultural and ethnic perspective in the study of parenting styles and prosocial behaviors.",35,130,49,73,Psychology; Prosocial behavior; Bibliometrics; Parenting styles; Empathy; Scientific production; Bibliographic search; Web of science; Social psychology,,,,,https://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S2215-35352021000100049 https://revista-ciencia-tecnologia.ucr.ac.cr/index.php/actualidades/article/download/39958/46376 https://revistaclinicahsjd.ucr.ac.cr/index.php/actualidades/article/download/39958/46376 https://revistaclinicahsjd.ucr.ac.cr/index.php/actualidades/article/view/39958,http://dx.doi.org/10.15517/ap.v35i130.39958,,10.15517/ap.v35i130.39958,3175736669,,0,,4,true,cc-by-nc-nd,gold -014-129-634-820-525,Bibliometrix analysis of medical tourism,2021-05-07,2021,journal article,Health services management research,17581044; 09514848,SAGE Publications,United Kingdom,Maura Campra; Patrizia Riva; Gianluca Oricchio; Valerio Brescia,"Medical tourism is an expanding phenomenon. Scientific studies address the changes and challenges of the present and future trend. However, no research considers the study of bibliometric variables and area of business, management and accounting. This bibliometric analysis discovered the following elements: (1) The main articles are based on guest services, management, leadership principles applied, hotel services associated with healthcare, marketing variables and elements that guide the choice in medical tourism; (2) The main authors do not deal with tourism but are involved in various ways in the national health system of the countries of origin or in WHO; (3)cost-efficiency and analytical accounting linked to medical tourism structures and destination choices are not yet developed topics.",35,3,9514848211011738,188,Business; Health care; Marketing; Tourism; Medical tourism; National health; Future trend; Hotel services; Bibliometric analysis; Phenomenon,bibliometrix; biblioshiny; medical tourism; medical tourism agenda; medical tourism management,Delivery of Health Care; Health Facilities; Humans; Medical Tourism,,,https://journals.sagepub.com/doi/full/10.1177/09514848211011738 https://iris.unito.it/handle/2318/1788580 https://journals.sagepub.com/doi/pdf/10.1177/09514848211011738 https://pubmed.ncbi.nlm.nih.gov/33957813/ https://www.ncbi.nlm.nih.gov/pubmed/33957813,http://dx.doi.org/10.1177/09514848211011738,33957813,10.1177/09514848211011738,3157897857,PMC9277331,0,001-737-771-508-850; 001-996-624-628-357; 003-054-781-765-340; 004-717-158-723-246; 005-290-963-135-232; 009-061-109-596-861; 011-096-511-036-16X; 011-705-192-730-226; 012-965-006-284-099; 013-037-004-259-636; 013-507-404-965-47X; 015-322-978-422-96X; 017-750-600-412-958; 018-629-828-238-660; 019-827-342-636-718; 020-630-911-952-048; 021-038-794-595-785; 024-277-625-289-59X; 026-148-957-958-229; 026-193-311-919-207; 026-845-733-807-089; 027-758-012-894-144; 028-790-718-552-716; 032-987-793-104-159; 032-999-172-139-947; 033-257-151-871-753; 034-837-265-172-536; 035-667-136-857-78X; 035-893-403-334-680; 037-036-602-845-527; 040-124-979-014-166; 040-864-493-066-680; 040-978-884-950-786; 042-266-722-692-363; 045-157-084-317-986; 045-173-800-509-875; 047-134-478-431-993; 049-479-142-025-023; 049-652-683-342-562; 051-629-985-687-183; 055-457-167-412-855; 059-602-684-629-538; 061-504-912-478-915; 062-910-676-930-876; 063-439-394-239-344; 063-949-285-738-267; 064-517-046-797-486; 065-088-963-343-469; 065-551-247-073-738; 067-280-512-491-940; 073-225-229-833-955; 076-072-660-867-452; 077-360-907-453-01X; 079-672-272-633-660; 081-943-574-024-194; 083-053-194-465-981; 085-214-676-685-052; 088-142-299-750-945; 091-905-967-425-20X; 093-047-769-656-730; 094-603-098-667-754; 103-144-839-254-813; 104-203-590-241-163; 104-212-051-085-493; 104-861-106-260-472; 106-469-522-607-873; 113-250-668-338-52X; 114-496-719-279-539; 136-856-637-637-018; 140-874-917-238-605; 142-188-925-681-415; 155-161-871-068-798; 157-520-729-759-47X; 158-821-112-463-586; 166-666-827-252-574; 175-398-849-659-808,50,true,cc-by-nc,hybrid -014-154-801-914-479,Modern international large-scale assessment in education: an integrative review and mapping of the literature,2021-07-30,2021,journal article,Large-scale Assessments in Education,21960739,Springer Science and Business Media LLC,,Daniel Hernández-Torrano; Matthew Courtney,"Research in international large-scale assessment (ILSA) has become an increasingly popular field of study in education. Consequently, interest and debate in the field by practitioners, researchers, policymakers, and the public has grown over the past decades. This study adopts a descriptive bibliometric approach to map modern research on ILSA in education and provide an up-to-date picture of the recent developments and structure of the field. The analysis of 2,233 journal articles indexed in the Web of Sciences database revealed that ILSA research in education is an emerging field in a stage of exponential growth that has become increasingly international with recent substantive contributions from China, Spain, and Turkey. Research in the field is currently produced by a tupid network of scholars with diverse geographical backgrounds that engage frequently in national and international research collaborations. Also, the field is relatively interdisciplinary and has developed grounded on nine differentiated historical paths. The PISA program has received the greatest attention in the field, and a wide variety of topics have been addressed in the literature in the last decades, including equity and quality education, globalization and education policy, measurement and statistics, student motivation and self-concept, and interpersonal relationships. The paper concludes by pointing to the potential of future ILSA research to make use of new more relevant instrumentation, data linkages, and trans-regional collaborations.",9,1,1,33,Variety (cybernetics); Political science; Bibliometrics; Educational assessment; Globalization; Equity (finance); Public relations; Scale (social sciences); Education policy; Interpersonal relationship,,,,,https://link.springer.com/content/pdf/10.1186/s40536-021-00109-1.pdf https://largescaleassessmentsineducation.springeropen.com/articles/10.1186/s40536-021-00109-1 https://eric.ed.gov/?q=source%3A%22Large-scale+Assessments+in+Education&id=EJ1303403 https://research.nu.edu.kz/en/publications/modern-international-large-scale-assessment-in-education-an-integ,http://dx.doi.org/10.1186/s40536-021-00109-1,,10.1186/s40536-021-00109-1,3189879141,,0,001-775-362-273-541; 002-052-422-936-00X; 003-254-479-923-236; 004-346-873-594-13X; 007-257-259-120-545; 007-337-121-835-724; 008-827-716-963-897; 009-286-240-384-618; 010-194-028-604-828; 011-441-712-429-554; 012-114-389-955-80X; 012-192-709-856-792; 013-507-404-965-47X; 019-372-528-120-834; 019-610-902-699-235; 022-587-427-682-463; 022-810-439-077-235; 023-429-491-342-909; 024-581-946-291-179; 024-774-610-198-182; 024-836-984-159-090; 027-048-457-606-399; 027-473-178-518-49X; 027-492-194-155-91X; 029-032-185-486-085; 030-049-517-445-80X; 034-368-659-107-201; 034-413-025-043-47X; 034-594-096-267-572; 035-001-331-438-82X; 036-182-111-625-254; 036-234-219-347-120; 036-458-324-352-776; 037-815-640-424-494; 038-309-130-943-264; 038-609-566-666-16X; 040-960-845-600-104; 041-432-297-475-476; 042-313-220-309-191; 045-391-738-675-420; 045-422-273-148-899; 051-720-046-820-65X; 052-350-255-499-170; 055-440-631-505-043; 055-781-625-349-393; 057-389-110-368-33X; 058-258-375-530-01X; 060-476-690-438-210; 063-167-178-679-306; 065-255-282-339-937; 066-252-741-506-46X; 068-396-154-971-952; 069-382-416-491-748; 070-137-486-683-979; 071-449-654-098-71X; 075-845-138-408-136; 079-439-801-436-216; 082-829-710-727-538; 085-456-910-106-920; 087-674-496-421-543; 087-809-394-504-132; 090-436-377-864-370; 092-498-441-912-872; 094-477-242-022-244; 094-920-619-504-424; 095-916-827-604-408; 098-512-535-617-969; 099-283-435-821-823; 102-007-988-019-924; 102-812-925-698-378; 114-308-227-208-207; 119-412-769-696-243; 124-089-382-014-491; 125-428-611-593-678; 126-629-114-553-293; 129-469-632-308-940; 130-135-515-780-571; 131-442-192-587-190; 132-359-866-551-506; 132-946-951-460-277; 133-737-453-363-664; 135-582-514-510-701; 141-200-607-894-303; 147-161-295-259-149; 148-095-130-416-461; 149-330-237-701-944; 159-306-125-917-84X; 161-450-182-484-516; 163-164-748-408-340; 175-999-610-558-865; 178-660-106-361-779; 179-470-401-422-369; 195-385-821-649-563; 195-768-929-992-951,31,true,cc-by,gold -014-173-261-762-075,Two Decades of International Business and International Management Scholarship on Africa: A Review and Future Directions,2023-07-27,2023,journal article,Management International Review,09388249; 18618901,Springer Science and Business Media LLC,Germany,Debmalya Mukherjee; Saumyaranjan Sahoo; Satish Kumar,,63,6,863,909,Scholarship; Context (archaeology); Corporate governance; Entrepreneurship; Sociology; Citation; International business; Corporate social responsibility; Thematic analysis; Political science; Social science; Regional science; Engineering ethics; Public relations; Management; Qualitative research; Economics; Engineering; Geography; Archaeology; Law,,,,,,http://dx.doi.org/10.1007/s11575-023-00513-5,,10.1007/s11575-023-00513-5,,,0,000-115-252-022-223; 000-779-767-050-495; 001-220-643-155-243; 002-222-845-974-541; 002-755-963-630-346; 004-008-618-215-495; 004-333-438-389-024; 005-146-653-142-924; 005-608-806-925-262; 006-116-860-121-455; 006-769-629-388-93X; 007-262-514-014-026; 008-054-465-644-768; 008-130-903-068-855; 008-304-559-991-380; 008-558-341-993-164; 009-311-418-504-608; 011-311-245-938-660; 011-517-938-945-277; 011-844-261-336-688; 012-045-865-870-967; 012-167-265-049-142; 012-591-611-952-995; 012-945-022-934-76X; 013-414-738-504-419; 013-507-404-965-47X; 014-900-480-660-368; 015-098-755-676-90X; 015-633-157-878-677; 015-813-182-250-871; 016-116-450-801-012; 016-200-443-009-424; 017-462-972-148-32X; 019-387-794-931-527; 019-968-145-374-471; 020-738-856-624-387; 020-851-012-071-369; 020-975-734-237-812; 021-092-673-319-300; 021-202-012-053-466; 021-977-545-948-274; 022-749-267-318-425; 023-659-641-822-021; 023-925-877-108-990; 023-967-974-245-722; 024-379-371-918-823; 024-544-048-219-156; 024-729-895-652-664; 025-796-975-981-472; 026-086-483-051-244; 026-796-404-843-451; 026-866-342-933-208; 027-801-716-468-718; 028-206-138-218-564; 028-927-071-448-137; 030-350-016-793-606; 030-781-896-214-039; 031-739-231-019-607; 032-009-926-296-231; 032-110-047-804-486; 033-491-938-690-10X; 033-971-548-281-995; 037-893-358-806-556; 038-032-145-484-575; 040-293-966-059-485; 040-676-981-395-696; 040-707-618-737-70X; 042-051-218-397-017; 043-256-257-882-889; 043-616-224-272-781; 044-791-566-825-766; 045-213-405-382-345; 045-254-987-848-512; 045-380-930-461-322; 046-992-864-415-70X; 048-116-710-508-818; 048-860-378-930-106; 048-869-500-449-780; 050-314-317-696-110; 050-609-067-982-963; 051-210-332-797-454; 051-537-481-216-208; 051-719-141-885-197; 052-336-839-622-602; 052-981-363-230-532; 053-098-943-839-25X; 053-299-603-309-210; 053-786-289-552-578; 053-939-191-401-776; 054-535-027-002-859; 055-455-985-366-222; 055-759-084-512-002; 056-258-482-833-494; 057-147-487-900-603; 057-740-937-906-285; 057-746-600-385-880; 058-112-948-240-916; 058-684-856-973-497; 059-194-763-344-864; 059-518-313-146-447; 059-519-145-470-081; 059-753-847-466-699; 060-202-083-675-881; 060-905-515-004-135; 061-027-495-758-860; 061-737-872-116-836; 061-802-871-902-526; 062-297-232-786-647; 063-085-822-993-592; 064-361-321-854-708; 066-006-587-657-054; 066-511-279-711-554; 067-068-504-896-413; 067-238-698-355-939; 068-758-055-889-932; 071-553-465-472-821; 072-442-679-253-477; 072-675-235-004-557; 072-949-275-069-510; 073-419-272-011-266; 073-779-233-031-589; 073-950-215-889-001; 074-169-693-118-819; 074-699-060-535-274; 074-733-422-682-770; 075-913-159-899-343; 078-769-791-895-317; 079-305-214-003-404; 080-192-944-581-094; 080-294-980-130-298; 080-514-905-729-817; 081-316-464-102-574; 081-425-623-267-046; 082-251-611-064-718; 082-254-763-650-285; 082-502-135-262-150; 082-592-024-524-340; 083-349-163-489-078; 085-371-708-701-686; 085-612-324-595-532; 088-801-553-346-881; 089-186-187-009-360; 089-907-265-844-175; 090-793-517-587-017; 091-142-327-288-689; 092-353-700-158-724; 092-455-019-776-027; 092-643-747-912-97X; 092-869-169-821-524; 093-487-315-971-006; 093-537-807-403-032; 093-759-322-168-015; 094-449-042-929-900; 096-061-214-240-715; 096-327-414-025-679; 097-055-311-281-32X; 098-016-788-807-450; 098-726-748-134-913; 101-966-970-999-060; 102-573-542-205-745; 103-572-753-034-159; 103-892-782-732-354; 106-873-808-099-629; 106-920-839-646-292; 107-872-596-069-867; 111-911-102-968-883; 116-415-723-179-501; 118-072-113-904-607; 118-660-434-767-085; 118-946-385-190-518; 119-337-820-887-225; 123-764-630-254-41X; 126-079-466-863-988; 126-790-545-690-215; 127-018-681-218-41X; 129-685-285-923-59X; 130-095-349-702-100; 130-137-664-125-289; 132-401-362-970-279; 132-954-318-916-523; 132-989-437-076-213; 133-849-404-964-056; 134-268-574-950-790; 135-319-172-415-633; 138-175-032-268-298; 138-906-325-732-396; 140-801-383-194-566; 141-529-093-432-892; 144-866-496-844-046; 147-301-994-998-225; 149-618-569-148-404; 150-820-143-915-180; 152-376-968-691-358; 152-620-372-579-236; 158-870-230-404-449; 159-760-147-351-234; 161-470-320-406-662; 168-883-940-843-011; 169-550-391-385-548; 173-193-064-283-466; 179-048-810-382-077; 180-260-400-089-357; 181-134-986-368-343; 184-381-685-031-71X,3,false,, -014-296-550-648-244,A MAPPING ANALYSIS OF BLOCKCHAIN APPLICATIONS WITHIN THE FIELD OF AUDITING,2020-12-31,2020,journal article,Muhasebe Bilim Dünyası Dergisi,25647164,Muhasebe Bilim Dunyas脹 Dergisi,,Melissa Cagle,"Blockchain technology has a wide scope of applicability for accounting and auditing purposes, separate from Bitcoin or other cryptocurrencies. However, although blockchain technology is identified as a popular topic within the field, there currently exists a lack of consensus on how it will be realistically applied. This paper aims to map the presently existing international auditing literature and offer clarity to an otherwise heterogeneous field. The mapping analysis will aid in examining the underlying theme employed within studies. Through the use of the Bibliometrix R-Package ""Biblioshiny"", a sample of 112 studies were downloaded from the Web of Science Core Collection and analyzed. This study's results show that the topic has gained increased international popularity and separated into distinct research streams; Encrypted Private and Secure Information Sharing, Distributed Ledger, Smart Contracts, Continuous Audit, Audit Trail and Tokenization. However, there still exists a research gap that must be addressed to hasten the adoption of blockchain technology in auditing.",22,4,695,724,Cryptocurrency; Audit; Data science; Information sharing; CLARITY; Tokenization (data security); Blockchain; Scope (project management); Computer science; Audit trail,,,,,https://dergipark.org.tr/en/pub/mbdd/issue/57901/746809 https://paperity.org/p/266833603/a-mapping-analysis-of-blockchain-applications-within-the-field-of-auditing https://dergipark.org.tr/en/download/article-file/1131506,http://dx.doi.org/10.31460/mbdd.746809,,10.31460/mbdd.746809,3106612680,,0,009-286-240-384-618; 010-752-888-026-654; 013-507-404-965-47X; 016-823-311-258-593; 018-283-327-297-018; 019-961-124-321-694; 021-621-233-548-426; 024-887-273-815-207; 026-916-024-218-228; 028-706-706-514-187; 030-975-651-068-227; 032-398-928-398-540; 035-842-514-393-915; 036-627-465-096-15X; 038-371-752-812-91X; 048-763-909-363-055; 049-153-793-957-588; 052-173-976-614-592; 057-041-381-714-997; 060-868-787-672-807; 061-410-793-269-952; 061-959-530-480-156; 076-991-386-599-906; 089-931-678-547-101; 098-418-292-544-142; 118-989-372-631-273; 129-561-979-416-248; 137-618-464-262-838; 150-183-344-427-723; 154-938-720-439-444; 155-619-739-180-661; 176-026-438-625-338; 185-219-943-473-213; 191-891-300-674-217,9,true,,gold -014-525-409-049-126,Knowledge mapping of frailty and surgery: a bibliometric and visualized analysis.,2024-09-27,2024,journal article,Langenbeck's archives of surgery,14352451; 14352443,Springer Science and Business Media LLC,Germany,Zhiwei Guo; Feifei Wang; Jiacheng Xu; Zhonggui Shan,"Frailty is common in surgical patients and is closely associated with postoperative outcomes.; This study employed bibliometric methods to summarize and analyze research related to frailty and surgery, comprehensively analyzing the research structure and providing visualized maps.; This study analyzed the volume of publications, countries, institutions, authors, journals, references, and keywords related to perioperative frailty in the Web of Science Core Collection from 1978 to 2024. Visual bibliometric analyses were conducted from multiple perspectives, including collaboration networks, citation analysis, and keyword clustering.; From 1978 to 2024, 21,879 authors from 95 countries and regions published 4,119 papers on perioperative frailty in 973 journals worldwide. The United States has the most publications, while Italy has the highest degree of international collaboration. The University of California System has the highest number of publications. The University of Kansas Medical Center is the institution with the highest centrality. The top nine authors in terms of publication volume are all from the USA. Bowers Christian A. is the most prolific author. The Journal of Vascular Surgery is the journal with the most publications. Current research directions include preoperative risk assessment of frailty, the relationship between frailty and postoperative complications, elderly frailty, and the relationship between frailty and sarcopenia. Research hotspots include risk stratification, postoperative delirium, the elderly, and sarcopenia.; This study has identified the research hotspots and trends in perioperative frailty. Our findings will enable researchers to understand this field's knowledge structure better and identify future research directions.; © 2024. The Author(s).",409,1,290,,Vascular surgery; Cardiothoracic surgery; Cardiac surgery; Abdominal surgery; Medicine; General surgery; MEDLINE; Surgery; Political science; Law,Bibliometric analysis; Elderly; Frailty; Surgery,"Bibliometrics; Humans; Frailty; Postoperative Complications/epidemiology; Aged; Surgical Procedures, Operative; Frail Elderly; Risk Assessment",,,,http://dx.doi.org/10.1007/s00423-024-03477-8,39331205,10.1007/s00423-024-03477-8,,PMC11436438,0,000-704-912-588-878; 001-164-047-686-933; 001-799-332-440-085; 001-984-834-835-663; 003-121-101-238-377; 005-450-357-370-275; 005-563-262-369-90X; 008-799-943-212-000; 011-441-514-957-380; 012-619-149-210-079; 013-037-349-438-656; 014-218-342-033-110; 018-522-721-409-562; 018-549-264-083-631; 019-220-723-550-589; 020-126-880-765-617; 020-878-636-595-697; 023-777-896-981-072; 023-901-479-565-399; 024-526-557-908-671; 027-897-684-170-050; 030-926-988-896-000; 036-705-539-547-613; 041-943-781-940-362; 041-999-211-248-115; 046-894-635-072-337; 049-086-862-826-243; 050-687-781-437-245; 052-924-839-001-890; 054-666-784-236-169; 056-863-710-639-841; 057-813-175-867-412; 058-164-262-035-525; 058-348-199-794-989; 062-393-450-060-81X; 065-895-232-933-503; 065-951-711-709-959; 068-476-025-580-111; 068-826-734-050-495; 070-287-911-075-741; 073-771-869-468-552; 074-558-609-442-456; 075-940-353-988-079; 076-254-682-698-917; 077-989-246-100-660; 080-390-585-386-621; 081-402-623-901-682; 082-229-793-186-407; 087-193-546-651-957; 089-383-588-649-580; 091-423-803-278-723; 094-560-875-536-074; 095-108-914-796-721; 097-782-454-458-701; 100-027-782-573-474; 102-967-144-132-650; 111-151-281-821-406; 122-641-457-486-906; 123-494-114-432-614; 133-939-523-841-728; 167-260-098-108-56X,0,true,cc-by-nc-nd,hybrid -014-566-352-973-158,The Role of Artificial Intelligence in Business Management: A Bibliometric Analysis,2025-05-23,2025,journal article,International Journal For Multidisciplinary Research,25822160,International Journal for Multidisciplinary Research (IJFMR),,ANJANA K; AMBILI V,"Abstract; This study has been designed to analyse the academic realm of AI in business management. The authors analysed the information they obtained from Scopus using R-Studio. The study quantitatively analyses publication trends, prominent authors, and thematic advancements in the field using the Bibliometrix R-package. According to the findings, there has been a notable increase in scholarly interest in recent years, along with changes in the focus of research and new fields of study. Liu Y is the most productive author and China has become a major contributor to this field of study, despite the fact that international cooperation is still quite limited.",7,3,,,,,,,,,http://dx.doi.org/10.36948/ijfmr.2025.v07i03.45827,,10.36948/ijfmr.2025.v07i03.45827,,,0,,0,false,, -014-744-560-680-607,Historical Perspectives on AI Applications in Business,2025-02-07,2025,book chapter,"Advances in Finance, Accounting, and Economics",23275677; 23275685,IGI Global,,Neeru Sidana; Ajay Sidana; Rohit Sood; Dewanshi Ghosh,"The purpose of studying the nexus between Artificial Intelligence and Business management through a bibliometric perspective is to systematically analyze and understand the existing body of scholarly literature on this topic.This paper aims to review articles related to Artificial Intelligence and Business management with the help of bibliometric analysis. A total number of 699 documents were drawn from the Scopus database out of which 593 articles were selected. To accomplish the overview of Artificial Intelligence and Business management Research, bibliometric techniques such as performance analysis and scientific mapping were applied. The data was also organized, analyzed, and presented using the Bibliometrix package. The study found that research on Artificial Intelligence and Business management has a significant growth rate of 7.05 percent. It was also discovered that Chen Y and Zhang Y has produced the most influential articles in this field and Industrial Marketing Management was the top-ranked journal.",,,165,198,Computer science; Business,,,,,,http://dx.doi.org/10.4018/979-8-3693-7357-6.ch009,,10.4018/979-8-3693-7357-6.ch009,,,0,000-645-861-878-332; 003-118-998-063-278; 014-766-294-857-568; 015-678-437-444-514; 016-265-810-198-704; 017-217-763-053-739; 020-138-810-671-760; 021-187-695-321-390; 022-387-415-895-182; 025-512-013-524-564; 028-997-837-018-901; 036-419-326-675-083; 049-062-601-267-141; 053-607-238-751-212; 068-850-003-935-61X; 069-428-700-193-626; 079-565-113-644-860; 082-403-368-606-408; 088-382-587-943-402; 103-737-714-502-610; 109-967-338-869-866; 114-974-292-292-999; 115-039-280-414-900; 115-616-971-208-863; 119-897-190-401-141; 122-763-530-742-650; 126-189-612-415-487; 128-671-364-070-384; 130-118-057-014-145; 162-574-330-667-965; 173-236-618-639-549; 174-152-118-981-039; 179-541-657-782-830; 180-850-236-514-090; 197-108-428-110-622,0,false,, -015-575-731-824-700,PERAN FINTECH DALAM MENGURANGI PERILAKU KONSUMTIF BERLEBIHAN: STUDI BIBLIOMETRIX VOSVIEWER,2024-10-31,2024,journal article,Jurnal Akuntansi dan Bisnis,27981789; 28089022,Universitas Sains dan Teknologi Komputer,,null Alief Rasika Jamil; null Sri Andriani; null Ahmad Fahruddin Alamsyah,Penelitian ini bertujuan untuk mengeksplorasi peran Fintech dalam mengurangi perilaku konsumtif yang berlebihan melalui pendekatan kuantitatif menggunakan metode bibliometrik. Fokusnya adalah fintech dan data diperoleh dari penelusuran jurnal nasional dan internasional yang terindeks di Google Scholar dan Sinta melalui Perish/Harzing. Teknik analisis data menggunakan metode bibliometrik dengan VOSviewer. Hasil penelitian menunjukkan bahwa berdasarkan studi bibliometrik dengan software algoritme VOSviewer. Terdapat 4 kluster dan 12 topik utama terkait Fintech. Penelitian ini memberikan implikasi dan konstribusi dalam memetakan topik yang relevan untuk penelitian mendatang dan memberikan wawasan tentang peran Fintech dalam mengatasi perilaku konsumtif yang berlebihan. Implikasinya dapat membantu dalam mengambil keputusan yang lebih baik terkait penggunaan Fintech serta untuk mencapai stabilitas keuangan dan kesejahteraan individu dan masyarakat.,4,2,1,10,Psychology,,,,,,http://dx.doi.org/10.51903/jiab.v4i2.752,,10.51903/jiab.v4i2.752,,,0,,0,false,, -015-906-314-997-92X,Bibliometric Analysis of a Comprehensive of Culture and Symbol in Character Animation during (2004–2024),2024-07-30,2024,journal article,Journal of Ecohumanism,27526801; 27526798,Creative Publishing House,,Chen Yang; Siti Salmi Jamali; Adzira Husain,"The analysis of academic research on animated characters in the animation industry effectively summarises the current state of scholarly research on animated characters through a variety of software tools such as CiteSpace, VOS viewer, HistCite, and Bibliometrix analysis, and visually charts and formulates this data. Through study and research, it that the United States is (278) the most prolific country, and the United States has the highest intermediary centrality, as well as the most Centre National de la Recherche Scientifique (CNRS) and PEOPLES R CHINA are the most cited organizations and Countries/Regions with the highest intermediary centrality and Countries/Regions with the highest citation explosiveness, respectively. This study also suggests possible challenges and future directions in character design for animated characters.",3,3,1427,1458,Character (mathematics); Symbol (formal); Animation; Character animation; Art; Literature; Linguistics; Computer animation; Philosophy; Mathematics; Geometry,,,,,https://ecohumanism.co.uk/joe/ecohumanism/article/download/3595/2562 https://doi.org/10.62754/joe.v3i3.3595,http://dx.doi.org/10.62754/joe.v3i3.3595,,10.62754/joe.v3i3.3595,,,0,,0,true,cc-by-nc-nd,hybrid -016-042-353-252-411,Research History and Trend of Scientific Research Management : Big Data Analysis Based on Bibliometrix Software,,2020,conference proceedings article,2020 International Conference on Computer Science and Management Technology (ICCSMT),,IEEE,,Jie Tong; Hanyuan Liang,"This study uses Bibliometrix to analyze the results of 570 literature search on scientific research management from Web of Science, and uses text analysis technology to explore the research results in this field for more than 20 years and the evolution of the theme.",,,351,354,The Internet; Engineering; Data science; Market research; Theme (narrative); Software; Information analysis; Web of science; Field (computer science); Big data,,,,Guangdong Ocean University,https://www.computer.org/csdl/proceedings-article/iccsmt/2020/866800a351/1u8pzyFFJx6,http://dx.doi.org/10.1109/iccsmt51754.2020.00079,,10.1109/iccsmt51754.2020.00079,3167296087,,0,010-874-717-062-277; 015-478-477-133-757; 031-281-523-741-130; 036-716-803-484-425; 038-192-468-423-323; 038-236-269-696-873; 049-019-336-217-19X; 049-303-089-841-806; 055-360-518-758-065; 064-158-733-438-328; 083-467-086-979-731; 083-956-206-068-885; 119-623-881-970-943,0,false,, -016-277-079-143-373,Estudo bibliométrico sobre Rankings Universitários,2021-05-21,2021,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Marisa Cubas Lozano; Denilson de Oliveira Sarvo,"A intenção deste trabalho foi caracterizar a produção científica sobre Rankings Universitários disponível na Web of Science e Scopus. Para isso foi usada a técnica de análise bibliometria e as ferramentas bibliometrix, VOSviewer, Mendeley e Excel.",,,,,Political science,,,,,https://zenodo.org/record/4779030,http://dx.doi.org/10.5281/zenodo.4779030,,10.5281/zenodo.4779030,,,0,,0,true,cc-by,gold -016-397-617-693-468,Machine learning in ovarian cancer: a bibliometric and visual analysis from 2004 to 2024.,2025-05-13,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Xian Zeng; Zude Li; Lilin Dai; Jiang Li; Luqin Liao; Wei Chen,"Ovarian cancer (OC) is a common malignant tumor in women, with poor prognosis and high mortality rates. Early diagnosis, screening, and prognostic prediction of OC have long been focal points and challenges in this field. In recent years, machine learning (ML) has gradually demonstrated its unique advantages in the early diagnosis, screening, and prognostic prediction of tumors, including OC.This study aims to analyze global development trends and research hotspots in the application of ML for OC, thereby providing a reference for future research directions.; We searched the Web of Science Core Collection (WoSCC) for all publications related to OC and ML from 2004 to 2024, conducting a quantitative analysis using VOSviewer, R software, and CiteSpace.; A total of 777 articles were retrieved.The number of publications related to ML and OC has grown continuously over the past 20 years.China led with 254 articles.The most prominent journals include Gynecologic Oncology, Nature, Clinical Cancer Research, Cancer Research, and Journal of Clinical Oncology.Research hotspots are: (a) ML-driven OC biomarker discovery and personalized treatment; (b) ML in tumor microenvironment analysis and resistance prediction; (c) ML in imaging-based diagnosis and risk stratification; (d) ML in multicenter OC studies.; ML in OC is currently in a developmental phase and shows promising potential for the future. This study provides researchers and clinicians with a more systematic understanding of research priorities and forthcoming developments in this area.; © 2025. The Author(s).",16,1,755,,Ovarian cancer; Computer science; Oncology; Artificial intelligence; Medicine; Cancer; Internal medicine,Artificial intelligence; Bibliometrics; Deep learning; Machine learning; Ovarian cancer,,,,,http://dx.doi.org/10.1007/s12672-025-02416-3,40360958,10.1007/s12672-025-02416-3,,PMC12075065,0,000-768-832-897-42X; 002-052-422-936-00X; 005-053-768-897-312; 006-531-229-960-378; 010-475-308-377-122; 012-458-685-002-72X; 013-507-404-965-47X; 016-050-506-702-023; 018-483-407-564-717; 019-690-569-075-391; 026-098-380-948-145; 030-506-174-994-508; 032-977-307-385-436; 033-967-222-435-104; 034-052-537-010-910; 036-230-785-356-410; 042-014-956-857-609; 042-492-530-461-048; 045-635-196-944-363; 049-111-773-635-367; 051-130-217-261-603; 053-079-675-949-968; 055-026-054-933-895; 057-099-791-187-298; 060-361-101-989-189; 064-400-499-357-900; 066-148-101-340-705; 067-917-168-966-235; 069-811-261-787-140; 070-710-274-158-872; 071-548-916-758-401; 073-795-888-198-697; 075-938-227-741-267; 077-170-755-705-304; 084-144-434-031-489; 084-245-373-947-612; 086-130-975-701-639; 091-149-851-557-314; 094-959-976-811-367; 095-868-565-486-283; 100-164-278-041-090; 100-368-627-411-331; 104-689-205-266-712; 107-003-334-996-148; 107-483-302-885-238; 130-798-448-630-326; 133-063-237-747-737; 133-388-549-135-719; 138-556-748-665-036; 141-770-516-078-794; 144-966-189-340-575; 151-951-448-536-727; 174-222-068-027-642; 176-345-927-444-27X; 178-088-172-032-813; 182-980-805-580-636; 189-762-397-637-080; 194-304-708-051-291; 198-079-023-307-140,0,true,cc-by,gold -016-855-995-808-934,Role of culture in sustainable development and sustainable built environment: a review,2021-08-10,2021,journal article,"Environment, Development and Sustainability",1387585x; 15732975,Springer Science and Business Media LLC,Netherlands,Nina Lazar; K. Chithra,,24,5,5991,6031,,,,,,,http://dx.doi.org/10.1007/s10668-021-01691-8,,10.1007/s10668-021-01691-8,,,0,000-563-844-012-087; 000-971-061-752-487; 002-665-882-586-778; 006-761-508-042-282; 007-222-449-432-881; 013-507-404-965-47X; 017-295-429-481-985; 020-064-853-621-246; 021-303-473-764-263; 027-690-220-065-414; 029-180-807-298-041; 029-390-737-095-278; 029-433-117-097-560; 030-894-861-122-266; 034-820-453-209-42X; 035-029-029-253-837; 040-858-202-655-119; 047-211-985-621-915; 050-668-653-369-037; 052-636-554-512-746; 053-267-951-465-31X; 054-889-365-235-864; 055-469-233-406-540; 075-017-002-937-895; 079-287-015-880-600; 080-580-679-612-375; 091-017-486-029-462; 097-766-665-058-708; 102-742-565-463-207; 109-386-080-905-19X; 112-579-975-969-513; 120-104-028-685-492; 127-485-475-331-342; 132-509-887-618-440; 132-777-837-807-121; 148-097-713-099-84X; 152-660-657-768-635; 153-066-344-992-921,35,false,, -016-984-439-141-148,Progress in geothermal gas research in the last 50 years: a bibliometric review,2025-04-08,2025,journal article,Earth Science Informatics,18650473; 18650481,Springer Science and Business Media LLC,Germany,Luyao Wang; Kai Liu; Li Wan; Shouchuan Zhang; Wuhui Jia; Junhan Guo; Tingxi Yu,,18,2,,,Geothermal gradient; Data science; Regional science; Library science; Environmental science; Computer science; Geology; Geography; Paleontology,,,,project of China Geological Survey; Basal Research Fund of the Chinese Academy of Geological Science,,http://dx.doi.org/10.1007/s12145-025-01868-z,,10.1007/s12145-025-01868-z,,,0,000-673-500-518-727; 002-121-991-237-651; 002-384-254-560-090; 002-403-313-726-611; 003-037-832-661-660; 003-370-769-437-47X; 005-816-086-962-319; 006-635-770-736-426; 007-685-372-536-64X; 009-109-283-679-777; 010-269-369-794-491; 011-456-262-012-832; 012-813-265-624-825; 013-293-462-978-470; 013-507-404-965-47X; 013-740-527-549-856; 014-081-905-407-426; 015-241-022-477-216; 016-090-711-703-064; 017-300-525-642-842; 018-231-132-350-953; 021-222-389-304-032; 022-525-585-058-371; 024-329-074-012-253; 026-041-452-199-669; 026-395-112-558-483; 026-713-233-520-351; 027-082-284-749-509; 028-445-426-257-013; 029-019-602-768-299; 031-137-375-415-643; 032-314-643-897-783; 033-074-713-550-408; 035-943-767-203-078; 037-065-288-427-791; 040-905-596-934-012; 048-794-368-881-838; 048-918-311-607-274; 051-729-411-433-158; 053-279-243-710-984; 054-818-565-070-154; 056-524-418-032-536; 056-688-354-435-336; 057-981-435-523-476; 058-232-107-050-495; 058-854-893-115-060; 059-260-025-601-622; 060-053-675-439-560; 060-234-382-252-72X; 061-107-225-364-108; 062-031-302-027-884; 062-955-759-403-659; 063-775-441-891-494; 064-138-321-183-893; 066-133-112-740-761; 066-509-360-278-767; 071-138-811-138-351; 071-977-994-897-197; 072-318-231-311-837; 076-826-884-109-026; 077-523-991-344-767; 078-777-965-734-805; 082-851-951-748-226; 089-468-749-828-460; 096-884-128-595-613; 098-124-323-119-939; 100-296-934-424-108; 101-299-381-098-532; 109-850-951-216-063; 110-310-971-222-063; 113-728-336-704-415; 121-724-568-341-838; 126-185-824-544-362; 129-008-128-778-191; 129-118-651-562-448; 144-154-123-262-515; 144-559-872-621-920; 164-818-571-315-048; 164-998-238-610-968; 168-654-073-187-546; 171-023-502-662-550; 191-836-481-707-206; 194-269-405-819-872; 194-521-089-048-528; 195-227-109-637-303; 199-264-782-917-143,0,false,, -017-902-891-341-28X,La conservación programada y su aplicación en la arquitectura: un análisis bibliométrico,2020-12-01,2020,journal article,Revista Tecnología en Marcha,22153241; 03793982,Instituto Tecnologico de Costa Rica,,Enmanuel Salazar-Ceciliano; Rosa Elena Malavassi-Aguilar,"Programmed conservation, a concept that has its origin in the works of the Italian art critic Giovanni Urbani published in 1976, has been strengthened in recent years as an instrument for conservation and valorization of the architectural heritage. This document consists of a bibliometric analysis of articles developed on this topic which are indexed in Scopus, within a period between 1988 and February 2020. Besides showing the behavior that this subject has had throughout history, this document identifies the main networks of countries, institutions and authors related to this matter, using a bibliometric analysis tool call Bibliometrix. The analysis includes 524 publications produced by 1206 authors from 501 different affiliations, where cultural conservation and monitoring of environmental factors are identified as the main fields related to the search.",33,4,79,88,Library science; Subject (documents); Period (music); Architectural heritage; Bibliometric analysis; Scopus; History,,,,,https://dialnet.unirioja.es/descarga/articulo/7727015.pdf https://repositoriotec.tec.ac.cr/handle/2238/13091 https://dialnet.unirioja.es/servlet/articulo?codigo=7727015,http://dx.doi.org/10.18845/tm.v33i8.5511,,10.18845/tm.v33i8.5511,3108617733,,0,,0,true,cc-by-nc-nd,gold -018-006-221-124-64X,Global trends and insights of telesurgery research: a bibliometric analysis of publications since the 21st century.,2025-04-14,2025,journal article,Surgical endoscopy,14322218; 09302794; 18666817,Springer Science and Business Media LLC,Germany,Guangdi Chu; Bo Guan; Xiaoyu Ji; Xue Yu; Ruonan Yang; Sevval Besli; Jianchang Zhao; Yuan Gao; Jianning Wang; Shuxin Wang; Jianmin Li; Haitao Niu,,39,5,3259,3284,Bibliometrics; Data science; Computer science; Regional science; Library science; Sociology,Bibliometric analysis; Research trends; Telemedicine; Telesurgery,Bibliometrics; Humans; Biomedical Research/trends; Telemedicine/trends; Robotic Surgical Procedures/trends,,National Key Research and Development Project of China (2023YFC2413405); Tianjin Science Fund for Distinguished Young Scholars (24JCJQJC00090); Major Scientific and Technological Innovation Project of Shandong Province (2022CXGC020505); Taishan Scholar Foundation of Shandong Province (tstp20221165),,http://dx.doi.org/10.1007/s00464-025-11697-2,40229598,10.1007/s00464-025-11697-2,,,0,002-052-422-936-00X; 002-791-643-200-564; 005-133-849-861-442; 005-149-268-190-405; 005-792-741-593-182; 006-256-409-102-916; 009-096-369-393-729; 010-207-513-276-231; 010-388-589-253-234; 010-540-044-618-532; 010-879-940-962-377; 012-163-246-278-988; 013-507-404-965-47X; 013-677-954-928-51X; 015-565-673-103-913; 016-732-611-432-801; 017-120-198-703-610; 022-004-343-500-709; 023-874-624-909-020; 025-280-151-436-327; 026-395-112-558-483; 027-535-111-650-593; 028-546-215-150-139; 030-685-575-546-323; 031-578-904-190-51X; 031-785-300-034-534; 032-730-611-440-052; 033-095-593-279-897; 034-770-754-339-84X; 036-505-288-090-607; 039-180-925-121-346; 039-567-184-262-85X; 039-705-951-993-606; 040-205-529-364-008; 040-900-175-024-915; 041-683-736-969-07X; 041-799-130-184-31X; 045-621-692-054-696; 046-053-521-482-382; 046-860-691-958-727; 047-782-832-294-545; 048-444-046-421-951; 048-643-465-409-131; 054-790-944-127-438; 056-043-584-941-447; 058-077-642-298-487; 060-135-695-722-848; 063-946-257-800-592; 071-427-030-884-213; 071-648-953-648-71X; 072-714-469-198-840; 075-394-289-924-998; 078-645-924-007-324; 079-717-278-180-769; 081-074-228-774-011; 086-922-625-515-364; 091-539-759-385-613; 095-095-685-632-562; 101-957-087-111-97X; 103-149-954-283-057; 104-592-931-992-70X; 105-837-238-605-141; 106-812-837-189-253; 107-262-715-167-286; 110-519-616-076-10X; 111-427-364-394-045; 113-837-238-034-174; 114-028-850-896-64X; 114-858-465-148-269; 125-472-763-707-417; 131-984-278-067-184; 140-211-179-336-90X; 142-611-223-554-361; 142-911-796-516-017; 144-297-739-128-435; 146-012-486-303-581; 150-023-754-670-993; 167-437-710-085-589; 169-911-345-358-734; 170-785-854-594-138; 177-535-479-646-663; 181-968-980-798-685; 182-424-921-620-642; 193-869-495-175-611; 199-702-996-852-805,0,false,, -018-049-633-412-47X,Mindfulness dalam Perspektif Neuropsikologi: Analisis Bibliometrik,2024-10-31,2024,journal article,Suksma: Jurnal Psikologi Universitas Sanata Dharma,27454185; 14129426,Sanata Dharma University,,Antonius Nandiwardana,"Mindfulness is gaining prominence in academic community particularly in neuropsychology. This research aims to conduct a bibliometric analysis of neuropsychology and brain research on mindfulness. 929 documents from Scopus database were analyzed with Bibliometrix software. The retrieved data regarding institutions, journal titles, countries, authors, and keywords. The analysis is focused on the research trend, the performance, and the collaboration network. The result indicates that neuropsychology and brain research on mindfulness were conducted from 1994 – 2023. The highest peak in the total production of neuropsychology research articles on mindfulness is 2022 with 142 documents. In addition, the data shows that certain authors, countries, and institutions contribute greatly to neuropsychology research on mindfulness. There are social interactions among authors, institutions, and countries. Future trends in this area of research will focus on topics related to depression, meditation, psychotherapy, and executive function. The results of this study provide insight into the growing trends in neuropsychology studies on mindfulness and data to assist researchers in identifying research gaps.",5,3,278,295,Mindfulness; Psychology; Political science; Philosophy; Psychotherapist,,,,,https://e-journal.usd.ac.id/index.php/suksma/article/download/7957/4356 https://doi.org/10.24071/suksma.v5i3.7957,http://dx.doi.org/10.24071/suksma.v5i3.7957,,10.24071/suksma.v5i3.7957,,,0,,0,true,,bronze -018-119-261-813-838,The impact of molecular markers in common bean through a scientometric approach,2021-06-21,2021,journal article,Euphytica,00142336; 15735060,Springer Science and Business Media LLC,Netherlands,João Matheus Kafer; Débora Regiane Gobatto; Leomar Guilherme Woyann; Eliane Carneiro; Gabriela Rodrigues da Silva; Taciane Finatto,,217,7,1,12,Comparative genomics; Whole genome sequencing; Phaseolus; Molecular marker; Colletotrichum lindemuthianum; Snp markers; Computational biology; Selection (genetic algorithm); Genetic diversity; Biology,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,https://link.springer.com/article/10.1007/s10681-021-02879-9,http://dx.doi.org/10.1007/s10681-021-02879-9,,10.1007/s10681-021-02879-9,3173375306,,0,002-052-422-936-00X; 003-426-485-301-765; 004-908-835-378-518; 005-309-984-664-35X; 011-315-723-898-965; 013-507-404-965-47X; 020-277-973-020-41X; 023-188-324-359-936; 028-101-983-856-685; 028-629-037-886-509; 028-670-626-526-397; 030-241-155-554-848; 035-231-601-050-133; 038-392-911-328-133; 041-916-834-777-148; 043-929-354-412-444; 046-535-368-929-302; 053-333-388-998-75X; 053-719-784-683-508; 055-209-130-381-562; 055-571-054-128-574; 065-981-425-880-648; 074-752-369-969-628; 081-883-957-592-517; 094-580-374-421-445; 102-053-309-857-692; 105-014-196-000-189; 119-453-062-348-537; 122-194-114-016-759; 145-027-937-192-40X; 150-325-162-873-23X,1,false,, -018-404-105-169-350,Conceptualising and measuring social media engagement: A systematic literature review,2021-08-11,2021,journal article,Italian Journal of Marketing,26623323; 26623331,Springer Science and Business Media LLC,,Mariapina Trunfio; Simona Rossi,"AbstractThe spread of social media platforms enhanced academic and professional debate on social media engagement that attempted to better understand its theoretical foundations and measurements. This paper aims to systematically contribute to this academic debate by analysing, discussing, and synthesising social media engagement literature in the perspective of social media metrics. Adopting a systematic literature review, the research provides an overarching picture of what has already been investigated and the existing gaps that need further research. The paper confirms the polysemic and multidimensional nature of social media engagement. It identifies the behavioural dimension as the most used proxy for users' level of engagement suggesting the COBRA model as a conceptual tool to classify and interpret the construct. Four categories of metrics emerged: quantitative metrics, normalised indexes, set of indexes, qualitative metrics. It also offers insights and guidance to practitioners on modelling and managing social media engagement.",2021,3,267,292,,,,,Università Parthenope di Napoli,,http://dx.doi.org/10.1007/s43039-021-00035-8,,10.1007/s43039-021-00035-8,,,0,000-522-359-413-150; 001-362-304-853-446; 004-330-741-688-621; 007-861-027-320-346; 008-550-517-809-740; 009-286-240-384-618; 013-507-404-965-47X; 013-617-047-361-594; 015-298-891-455-569; 015-763-535-993-708; 015-916-736-246-332; 019-000-886-960-393; 025-302-119-966-613; 026-601-367-644-468; 028-185-925-851-780; 028-839-628-255-368; 030-407-935-771-04X; 030-593-646-841-47X; 034-571-063-433-827; 034-911-918-171-593; 037-375-019-172-245; 039-649-908-108-68X; 040-362-818-631-933; 040-468-290-002-05X; 041-201-172-947-996; 042-093-271-633-934; 043-017-320-335-266; 045-380-302-937-748; 046-588-839-541-785; 046-987-161-956-95X; 049-116-527-459-321; 049-492-653-298-628; 049-986-345-654-678; 054-525-572-609-219; 054-582-395-489-471; 054-802-377-705-750; 056-704-702-501-49X; 059-217-036-057-294; 059-330-198-396-63X; 059-509-496-525-33X; 059-714-141-652-914; 063-783-311-162-832; 066-817-022-275-453; 070-612-446-670-719; 073-192-809-799-863; 076-767-409-442-439; 078-250-940-872-821; 079-710-742-421-342; 085-300-287-100-525; 086-186-554-515-806; 088-936-051-428-500; 092-065-135-201-948; 097-236-979-157-970; 097-845-780-479-167; 098-222-911-551-92X; 102-694-788-795-301; 107-869-572-964-552; 113-143-866-754-387; 115-577-300-840-316; 116-017-667-784-964; 116-672-998-536-157; 119-789-986-772-126; 124-427-125-763-191; 151-314-980-254-302; 154-542-511-808-660; 167-346-933-471-045; 167-792-347-031-549; 171-425-384-364-916; 188-056-495-268-536,70,true,cc-by,hybrid -019-107-065-906-488,Understanding Social Presence in Extended Reality: A Bibliometric Analysis Based on Web of Science Database Using Bibliometrix RStudio and Citespace,2024-09-13,2024,conference proceedings article,2024 4th International Conference on Educational Technology (ICET),,IEEE,,Yue Zhang; Hasnah Binti Mohamed; Mohd Shafie Rosli; Qilong Yu,,,,603,608,Computer science; Web of science; Database; Data science; MEDLINE; Biology; Biochemistry,,,,,,http://dx.doi.org/10.1109/icet62460.2024.10869048,,10.1109/icet62460.2024.10869048,,,0,005-157-217-876-247; 008-977-744-925-955; 010-442-924-794-711; 010-450-243-438-690; 010-547-438-975-817; 013-507-404-965-47X; 025-928-723-507-418; 027-936-558-282-405; 047-977-890-599-144; 050-053-442-536-172; 066-712-125-190-144; 068-675-835-492-473; 071-741-631-576-254; 077-237-543-411-746; 077-390-749-648-512; 077-391-433-417-288; 096-468-953-797-247; 103-819-742-658-857; 123-930-404-572-031; 164-446-199-347-486; 168-324-802-938-441; 170-735-746-720-592,0,false,, -019-250-601-936-587,Emerging trends on the mechanism of pelvic organ prolapse from 1997 to 2022: visualization and bibliometric analysis.,2023-06-07,2023,journal article,Frontiers in medicine,2296858x,Frontiers Media SA,Switzerland,Xia Yu; Wenyi Lin; Xuemei Zheng; Li He; Zhenglin Yang; Yonghong Lin,"At present, there is no feature description of the mechanism of pelvic organ prolapse (POP) in the literature. This study aimed to map the emerging trends regarding the mechanism of POP from inception to 2022 by bibliometric analysis and to analyze its research hotspots and frontiers.; We downloaded pertinent publications from inception to 2022 from the Web of Science Core Collection (WoSCC) on 30 June 2022. The data were then examined using the Bibliometrix program in R (Version 4.1.0), CiteSpace software, the Online Analysis Platform of Literature Metrology (https://bibliometric.com), and a bibliometrix online interface.; A total of 290 qualified records on the mechanism of POP were identified and included in the analysis. The most productive journal was International Urogynecology Journal. Bump RC and Olsen AL were the most cited authors. Extracellular matrix, collagen, apoptosis, elastin, oxidative stress, gene expression, matrix metalloproteinase, and tissue engineering were among the 25 most relevant terms. According to the analysis of trending topics, tissue engineering has become a new research hotspot.; Extracellular matrix remodeling, oxidative stress and apoptosis are the three main directions for studying the mechanism of POP. In addition, tissue engineering has become a new research hotspot. In the future, in-depth research on the interaction between different mechanisms will be carried out, and attempts will be made to combine biomimetic materials and seed cells to achieve the regeneration and reconstruction of POP-related organs.; Copyright © 2023 Yu, Lin, Zheng, He, Yang and Lin.",10,,1158815,,Mechanism (biology); Visualization; Medicine; Data science; Computer science; Data mining; Physics; Quantum mechanics,CiteSpace; bibliometric analysis; extracellular matrix remodeling; mechanism; oxidative stress; pelvic organ prolapse,,,Natural Science Foundation of Sichuan Province,https://www.frontiersin.org/articles/10.3389/fmed.2023.1158815/pdf https://doi.org/10.3389/fmed.2023.1158815,http://dx.doi.org/10.3389/fmed.2023.1158815,37351071,10.3389/fmed.2023.1158815,,PMC10282136,0,002-365-229-595-01X; 007-472-731-552-918; 007-500-155-247-91X; 008-116-690-078-724; 013-446-159-801-335; 016-531-385-392-774; 022-278-443-325-010; 023-484-235-881-534; 024-745-743-866-129; 027-900-024-479-073; 031-217-111-169-59X; 037-377-830-612-018; 045-359-929-348-65X; 046-509-968-191-322; 048-994-307-027-706; 049-718-205-538-99X; 049-826-137-983-167; 050-360-782-131-489; 058-214-540-019-254; 062-293-647-364-843; 081-185-007-275-915; 082-729-838-766-781; 092-503-511-836-101; 094-588-592-773-031; 107-584-512-578-693; 108-670-723-556-15X; 124-135-883-694-792; 128-527-004-244-161; 188-563-601-697-278,5,true,cc-by,gold -019-675-884-166-351,Mobile-Health based physical activities co-production policies towards cardiovascular diseases prevention: findings from a mixed-method systematic review.,2022-03-01,2022,journal article,BMC health services research,14726963,Springer Science and Business Media LLC,United Kingdom,Gabriele Palozzi; Gianluca Antonucci,"Cardiovascular disease (CVD) is the first cause of death globally, with huge costs worldwide. Most cases of CVD could be prevented by addressing behavioural risk factors. Among these factors, there is physical and amateur sports activity (PASA), which has a linear negative correlation with the risk of CVD. Nevertheless, attempts to encourage PASA, as exercise prescription programmes, achieved little impact at the community-wide level. A new frontier to promote PASA is represented by mobile health tools, such as exergaming, mobile device apps, health wearables, GPS/GIS and virtual reality. Nevertheless, there has not yet been any evident turnabout in patient active involvement towards CVD prevention, and inactivity rates are even increasing. This study aims at framing the state of the art of the literature about the use of m-health in supporting PASA, as a user-centric innovation strategy, to promote co-production health policies aiming at CVD prevention.; A mixed-method systematic literature review was conducted in the fields of health and healthcare management to highlight the intersections between PASA promotion and m-health tools in fostering co-produced services focused on CVD prevention. The literature has been extracted by the PRISMA logic application. The resulting sample has been first statistically described by a bibliometric approach and then further investigated with a conceptual analysis of the most relevant contributions, which have been qualitatively analysed.; We identified 2,295 studies, on which we ran the bibliometric analysis. After narrowing the research around the co-production field, we found 10 papers relevant for the concept analysis of contents. The interest about the theme has increased in the last two decades, with a high prevalence of contributions from higher income countries and those with higher CVD incidence. The field of research is highly multi-disciplinary; most of documents belong to the medical field, with only a few interconnections with the technology and health policy spheres. Although the involvement of patients is recognized as fundamental for CVD prevention through PASA, co-design schemes are still lacking at the public management level.; While the link between the subjects of motor activity, medicine and technology is clear, the involvement of citizens in the service delivery process is still underinvestigated, especially the issue concerning how ""value co-creation"" could effectively be applied by public agencies. In synthesis, the analysis of the role of co-production as a system coordination method, which is so important in designing and implementing preventive care, is still lacking.; © 2022. The Author(s).",22,1,277,,Medicine; Health promotion; Health informatics; Health care; Environmental health; Public health; Public relations; Nursing; Political science; Law,Bibliometric analysis; Cardiovascular Disease; Co-production; Health Policies; Healthcare; Mobile-health; Physical activity; Sports,Cardiovascular Diseases/prevention & control; Exercise; Health Policy; Health Services; Humans; Telemedicine,,"DEA, ""G. d'Annunzio"" University of Chieti-Pescara, Italy",https://bmchealthservres.biomedcentral.com/track/pdf/10.1186/s12913-022-07637-8 https://doi.org/10.1186/s12913-022-07637-8,http://dx.doi.org/10.1186/s12913-022-07637-8,35232456,10.1186/s12913-022-07637-8,,PMC8886562,0,000-241-551-145-749; 000-952-110-971-261; 001-196-091-321-540; 002-767-284-315-086; 002-857-359-952-127; 003-489-809-555-605; 003-704-266-927-01X; 004-775-935-700-15X; 006-248-654-496-031; 007-209-395-425-144; 007-998-547-046-00X; 008-359-947-827-302; 009-378-741-253-067; 009-656-975-530-634; 010-168-316-482-221; 011-291-927-143-392; 011-617-177-253-003; 011-769-478-159-734; 012-913-597-208-287; 013-064-772-768-277; 013-507-404-965-47X; 013-524-854-219-241; 013-541-969-076-695; 013-702-378-388-544; 013-790-625-436-789; 014-632-998-669-510; 015-902-749-741-618; 018-460-117-990-505; 019-021-834-717-685; 019-219-882-433-111; 019-486-241-448-715; 019-802-242-980-158; 020-737-280-744-380; 021-493-763-999-271; 023-730-138-633-564; 025-570-525-046-91X; 025-623-113-585-278; 026-408-609-226-214; 027-702-704-426-429; 028-177-752-042-378; 030-344-292-649-618; 031-009-334-666-239; 031-441-662-528-911; 031-531-051-422-754; 033-638-024-809-42X; 034-854-832-213-256; 035-355-916-629-355; 036-244-505-531-219; 036-611-539-101-286; 037-660-009-880-793; 038-056-303-693-310; 038-670-576-018-900; 039-043-659-378-411; 040-715-453-219-452; 041-241-986-984-880; 042-287-405-346-443; 042-643-842-375-021; 042-806-836-965-483; 042-863-257-786-22X; 049-108-154-399-097; 050-417-858-802-336; 050-942-598-868-878; 051-469-028-376-850; 051-772-206-356-783; 052-787-010-296-895; 053-655-227-481-25X; 054-018-766-408-793; 054-660-985-871-946; 055-960-055-616-106; 057-045-896-806-75X; 059-688-331-599-695; 059-854-787-251-92X; 060-303-732-916-538; 060-462-047-841-580; 060-886-626-515-391; 062-193-627-129-258; 062-730-234-612-995; 062-904-271-886-802; 066-654-462-852-038; 066-994-494-146-841; 067-188-420-828-786; 068-691-300-370-373; 069-870-844-911-860; 070-650-181-940-257; 070-905-661-656-978; 071-563-079-440-265; 072-651-850-529-834; 072-858-501-136-571; 073-367-985-641-83X; 075-347-197-222-102; 075-826-275-912-685; 076-412-590-067-879; 076-913-712-228-542; 077-584-315-270-44X; 077-943-154-469-897; 078-864-795-102-295; 078-875-817-958-03X; 079-558-285-421-967; 080-468-337-150-377; 081-661-059-266-839; 082-163-647-863-263; 085-300-287-100-525; 087-902-159-582-698; 088-920-842-502-408; 089-132-878-304-146; 091-614-943-931-140; 093-685-747-337-997; 094-477-710-497-049; 095-791-142-063-69X; 098-455-551-103-919; 099-726-084-084-04X; 104-568-865-292-886; 107-036-908-225-352; 110-016-354-092-323; 110-562-857-975-564; 120-295-919-189-710; 121-813-144-996-86X; 130-225-855-797-90X; 130-797-158-882-643; 133-178-557-798-031; 135-189-880-399-029; 136-099-802-626-617; 140-337-649-654-384; 143-029-675-633-119; 148-462-682-870-576; 171-041-145-350-880,7,true,"CC BY, CC0",gold -019-950-878-358-289,A Bibliometric-Systematic Analysis Of Post-Occupancy Evaluation Of Green Building Using Bibliometrix R-Tool,2025-06-19,2025,journal article,CIB Conferences,30674883,Purdue University (bepress),,Caleb Debrah; Albert P.C. Chan; Amos Darko; Eunice Akowuah; Judith Amudjie; Kofi A.B. Asare; Frank Ato Ghansah,,1,1,,,,,,,,,http://dx.doi.org/10.7771/3067-4883.1951,,10.7771/3067-4883.1951,,,0,,0,false,, -020-221-283-340-018,"Disaster risk assessment in Malaysia: current state, challenges, and future directions",2025-05-26,2025,journal article,Natural Hazards,0921030x; 15730840,Springer Science and Business Media LLC,Netherlands,Muhammad Wafiy Adli Ramli; Nor Eliza Alias; Zulfaqar Sa'adi; Yusrin Faiz Abdul Wahab; Azimah ABD Rahman,,,,,,Natural hazard; Current (fluid); Risk assessment; Risk analysis (engineering); Environmental planning; Engineering; Forensic engineering; Environmental science; Environmental resource management; Geography; Business; Computer science; Computer security; Meteorology; Electrical engineering,,,,Universiti Sains Malaysia,,http://dx.doi.org/10.1007/s11069-025-07360-7,,10.1007/s11069-025-07360-7,,,0,002-988-838-009-048; 006-365-100-233-689; 007-855-748-993-478; 007-966-079-724-095; 010-913-114-823-451; 013-808-827-342-281; 015-162-243-988-794; 022-513-943-296-663; 023-367-747-753-779; 028-207-633-334-866; 030-876-109-580-024; 036-100-568-901-536; 048-135-220-522-872; 048-776-878-980-191; 051-496-388-491-821; 057-076-670-944-086; 057-728-454-772-751; 062-808-715-790-300; 064-937-740-940-394; 066-772-931-109-624; 072-075-559-975-991; 074-922-320-086-962; 077-114-108-930-349; 080-378-161-642-490; 083-819-755-084-828; 087-459-024-521-608; 088-213-063-140-564; 089-111-990-365-595; 095-917-714-214-379; 099-246-576-591-408; 102-955-929-525-704; 103-390-108-437-388; 107-093-338-230-096; 107-099-247-443-755; 107-461-516-153-430; 109-618-710-188-907; 113-275-843-506-713; 115-492-966-243-638; 118-090-186-275-900; 122-264-927-753-474; 136-174-625-838-164; 136-805-111-889-552; 141-766-383-069-736; 145-755-260-567-630; 179-558-678-617-085; 183-879-297-963-760; 193-823-404-774-704; 198-103-804-977-793,0,false,, -020-472-235-794-994,The economics of forest carbon sequestration: a bibliometric analysis,2023-01-31,2023,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Pragati Verma; P. K. Ghosh,"Carbon sequestration in forests has increasingly captured the attention of scientists as a strategy for climate change mitigation and environmental sustainability. In this era of huge carbon emissions, being a low-carbon and cost-effective technology, the economic analysis of forest carbon sequestration holds higher importance for the successful implementation and intended outcomes. This study elucidates a scientometric view of the research structure and thematic evolution of economic studies on forest carbon sequestration based on 1439 articles over the time slice of 2001–2021. The bibliographic data have been retrieved from the Dimensions database, which accommodates a large coverage of research publications and also provides easy access to essential scholarly data and information. Vosviewer and Biblioshiny software tools have opted for visualisation and evaluation purposes of bibliometric data. This study employs various measures of bibliometric analysis like co-authorship, bibliographic coupling, citation and keyword analysis to find out the principal articles, authors, journals, most frequent keywords and highest publishing countries and institutions in this field, and the results show that the number of publications has escalated substantially in the last five years, the most cited article and most productive author are Popp A, 2017 (305 citations) and André P C Faaij (11 documents), respectively, Bradford’s law calculates 21 core journals out of total 503 journals, among which Forest Policy and Economics is at the top, and the most productive country and institution are the USA and University of Florida, respectively. The study also investigates key publishing subject categories, and the number of publications covered under each of the Sustainable Development Goals. The overall outcome of this bibliometric study confers an in-depth understanding of the various dimensions of economic analysis on forest carbon sequestration and its development pattern in the last 21 years and also provides emerging themes for future reference.",26,2,2989,3019,Carbon sequestration; Bibliometrics; Publishing; Sustainability; Library science; Citation; Web of science; Regional science; Data science; Political science; Environmental economics; Computer science; Geography; Economics; MEDLINE; Ecology; Carbon dioxide; Law; Biology,,,,,https://www.researchsquare.com/article/rs-1236338/latest.pdf https://doi.org/10.21203/rs.3.rs-1236338/v2,http://dx.doi.org/10.1007/s10668-023-02922-w,,10.1007/s10668-023-02922-w,,,0,000-013-313-522-452; 000-326-566-124-943; 001-124-713-413-480; 002-016-193-684-647; 002-052-422-936-00X; 002-491-666-747-453; 002-919-986-571-797; 004-788-915-388-253; 006-934-501-623-626; 007-022-995-409-922; 007-313-854-266-614; 008-022-692-924-923; 009-128-210-342-034; 011-301-822-302-672; 012-702-929-159-902; 013-507-404-965-47X; 013-524-854-219-241; 014-847-650-938-204; 015-784-280-206-495; 016-002-285-995-507; 017-146-468-093-265; 018-176-455-484-471; 018-231-132-350-953; 019-704-491-230-658; 019-857-870-915-742; 020-554-723-673-509; 021-616-239-594-590; 021-708-648-663-348; 022-777-713-688-169; 023-761-116-245-861; 025-933-777-068-47X; 025-995-680-392-269; 027-936-642-797-321; 031-585-270-135-468; 034-732-911-805-318; 036-681-224-728-176; 037-323-909-843-050; 038-305-597-319-221; 041-401-991-989-23X; 043-899-056-260-994; 046-204-187-077-669; 047-784-432-046-832; 047-798-635-805-939; 048-110-263-010-980; 048-625-124-295-755; 050-211-714-235-041; 051-843-348-130-830; 052-733-031-428-072; 053-165-154-858-375; 055-239-060-924-88X; 056-044-582-155-80X; 060-833-405-703-349; 062-716-169-321-524; 064-400-499-357-900; 065-866-727-629-121; 066-762-423-338-480; 070-154-788-763-370; 070-316-896-987-303; 071-903-355-299-99X; 074-590-346-984-770; 077-070-983-336-418; 080-222-988-268-82X; 082-233-464-106-711; 082-871-129-468-308; 083-382-915-064-254; 085-116-720-370-893; 085-541-265-907-587; 087-366-493-664-203; 088-025-097-377-449; 090-510-741-978-327; 092-578-397-280-221; 093-710-135-279-468; 094-656-037-501-354; 097-807-763-650-412; 100-876-740-488-155; 102-621-526-403-104; 107-252-712-719-015; 107-922-422-049-017; 111-635-774-589-896; 113-577-962-015-312; 117-322-108-857-861; 120-365-686-554-094; 124-671-502-876-795; 133-398-348-502-868; 134-625-694-898-707; 139-829-805-497-954; 140-351-683-975-801; 144-295-705-549-216; 151-000-889-192-209; 152-279-403-403-617; 157-474-590-628-517; 170-159-601-544-740; 186-148-626-913-52X; 197-348-791-252-716,12,true,,green -020-521-715-766-915,Perspectives on Migration and Financial Markets Research,2024-06-29,2024,journal article,Journal of Risk and Financial Management,19118074; 19118066,MDPI AG,,Juan David González-Ruiz; Camila Múnera-Sierra; Nini Johana Marín-Rodríguez,"This study comprehensively analyzes the relationship between migration and financial markets. We examine existing research on this subject using a scientometric and bibliometric approach. By employing VOSviewer and Bibliometrix tools, we introduce a novel methodology that enhances comprehension of this intricate relationship. The findings underscore two significant outcomes. Firstly, the impact of migration on financial markets is evident through the substantial flow of remittances and microfinance. Secondly, this study uncovers challenges hindering the integration of migrants into formal banking systems, thereby affecting financial market dynamics. This research deepens our understanding of migration’s implications on financial markets, offering practical insights that can guide policymakers and financial institutions in their decision-making processes.",17,7,272,272,Business; Financial market; Financial system; Finance,,,,,,http://dx.doi.org/10.3390/jrfm17070272,,10.3390/jrfm17070272,,,0,000-063-636-181-272; 001-836-230-852-249; 002-433-958-243-251; 005-940-919-490-108; 007-500-155-247-91X; 008-380-169-019-03X; 011-301-822-302-672; 013-507-404-965-47X; 016-007-077-248-665; 017-697-538-472-406; 017-891-674-388-048; 019-023-060-524-079; 034-104-789-062-612; 037-523-273-423-857; 037-815-640-424-494; 038-032-249-691-368; 040-177-646-696-84X; 041-678-656-895-596; 044-449-221-049-139; 048-989-493-647-565; 051-147-406-466-967; 056-685-573-918-641; 060-074-549-552-733; 060-784-290-267-429; 065-694-195-862-038; 066-745-398-906-807; 075-916-912-607-886; 078-593-529-455-491; 080-734-876-684-078; 088-080-372-321-354; 089-680-077-858-605; 092-016-909-865-182; 100-199-076-159-517; 100-599-984-849-401; 102-489-197-007-235; 112-203-978-922-504; 114-325-633-908-49X; 115-117-421-879-471; 119-311-043-772-339; 125-087-691-262-939; 128-369-413-304-494; 131-342-190-573-467; 138-988-234-387-373; 152-635-263-614-815; 160-772-793-109-649; 174-894-817-889-154; 176-180-475-378-466; 177-391-518-623-270; 178-423-201-712-734; 187-271-116-784-49X,1,true,,gold -020-595-211-521-481,Research Mapping of Trauma Experiences in Autism Spectrum Disorders: A Bibliometric Analysis. Bibliometrix file,2023-02-21,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Osvaldo Hernández-González; Andrés Fresno-Rodríguez; Rosario Spencer-Contreras; Raúl Tárraga-Mínguez; Daniela González-Fernández; Francisca Sepúlveda-Opazo,This is the Bibliometrix file of the paper entitled: Research Mapping of Trauma Experiences in Autism Spectrum Disorders: A Bibliometric Analysis.,,,,,Autism; Psychology; Computer science; Psychiatry,,,,,https://zenodo.org/record/7660174,http://dx.doi.org/10.5281/zenodo.7660174,,10.5281/zenodo.7660174,,,0,,0,true,cc-by,gold -020-744-380-836-237,Bibliometric analysis of artificial intelligence techniques for predicting soil liquefaction: insights and MCDM evaluation,2024-05-09,2024,journal article,Natural Hazards,0921030x; 15730840,Springer Science and Business Media LLC,Netherlands,Abdullah Hulusi Kökçam; Caner Erden; Alparslan Serhat Demir; Talas Fikret Kurnaz,,120,12,11153,11181,Multiple-criteria decision analysis; Hydrogeology; Natural hazard; Liquefaction; Environmental engineering science; Soil liquefaction; Engineering; Environmental science; Management science; Computer science; Geology; Operations research; Geotechnical engineering; Biogeosciences; Earth science; Oceanography,,,,,,http://dx.doi.org/10.1007/s11069-024-06630-0,,10.1007/s11069-024-06630-0,,,0,000-511-834-649-303; 001-221-039-680-118; 001-361-850-816-883; 004-409-406-366-627; 005-830-390-011-682; 009-042-699-445-225; 013-507-404-965-47X; 018-509-847-200-442; 022-320-662-941-514; 024-120-974-943-769; 026-295-909-393-008; 033-343-452-641-039; 034-207-033-629-588; 036-051-052-901-991; 036-967-161-804-429; 043-742-890-442-284; 049-247-625-165-87X; 053-983-924-968-859; 060-096-350-406-98X; 067-164-171-987-113; 076-789-448-040-157; 094-199-740-512-417; 094-434-894-944-738; 099-690-092-879-799; 100-706-754-938-928; 105-170-048-840-877; 107-870-460-374-994; 119-571-851-622-364; 123-475-605-514-696; 138-785-240-374-106; 141-200-607-894-303; 145-905-253-622-487; 148-840-953-180-127; 165-167-051-992-619; 174-603-960-773-434; 186-018-050-061-17X,2,false,, -020-821-064-494-497,Application of Predictive Analytics in Built Environment Research: A Comprehensive Bibliometric Study to Explore Knowledge Domains and Future Research Agenda,2023-05-16,2023,journal article,Archives of Computational Methods in Engineering,11343060; 18861784,Springer Science and Business Media LLC,Spain,Aritra Halder; Sachin Batra,,30,7,4299,4324,Scopus; Bibliographic coupling; Analytics; Data science; Computer science; Extant taxon; Citation; Knowledge management; Political science; Library science; MEDLINE; Evolutionary biology; Law; Biology,,,,,,http://dx.doi.org/10.1007/s11831-023-09938-5,,10.1007/s11831-023-09938-5,,,0,000-703-311-870-70X; 003-019-696-405-005; 004-515-795-552-499; 004-742-282-153-097; 005-057-984-478-196; 006-176-521-749-461; 006-933-514-166-132; 007-405-129-936-660; 007-556-678-693-591; 008-207-394-913-581; 009-163-301-642-159; 010-171-819-922-943; 010-296-819-535-109; 010-643-390-076-512; 011-792-082-731-55X; 012-411-581-367-865; 012-592-065-646-193; 013-507-404-965-47X; 014-344-743-475-347; 014-828-215-913-279; 015-324-597-340-02X; 017-757-190-228-163; 019-431-982-775-555; 020-348-689-260-614; 020-634-813-258-982; 022-459-398-762-328; 022-923-872-647-244; 023-790-194-714-048; 025-302-119-966-613; 025-521-368-245-497; 026-300-414-684-157; 026-637-296-324-321; 027-048-457-606-399; 027-523-465-692-127; 028-687-488-467-675; 029-559-457-316-954; 029-658-445-942-388; 031-068-930-656-926; 031-503-076-934-395; 031-727-255-739-440; 032-410-182-879-207; 033-127-677-566-360; 036-380-418-748-483; 036-693-844-737-40X; 037-612-614-036-965; 038-346-110-857-812; 039-222-181-198-262; 039-990-146-170-960; 040-561-076-500-185; 041-706-342-745-320; 044-528-564-618-933; 044-564-020-386-001; 045-233-501-137-794; 045-503-150-878-52X; 046-992-864-415-70X; 047-807-864-900-464; 050-115-943-347-813; 051-144-399-459-502; 051-647-739-244-271; 053-277-757-610-447; 053-598-695-896-482; 053-935-041-470-946; 057-314-157-944-895; 057-696-396-246-708; 057-803-697-074-453; 060-360-756-763-100; 061-379-286-788-384; 063-431-723-062-716; 063-434-981-222-421; 063-867-989-846-259; 064-952-668-345-050; 065-125-824-552-527; 068-192-592-333-673; 068-309-794-773-649; 070-087-179-496-636; 071-392-045-129-264; 073-192-468-199-578; 074-007-344-165-148; 074-513-370-242-735; 076-434-798-052-403; 077-520-927-765-686; 078-388-365-933-000; 081-027-237-232-28X; 081-798-833-690-792; 085-088-130-881-727; 091-713-641-244-920; 093-084-169-278-222; 094-754-714-040-807; 095-246-170-590-303; 096-635-911-194-312; 096-690-895-535-077; 098-290-793-422-83X; 102-081-759-760-837; 102-297-280-236-77X; 102-345-151-642-839; 103-740-777-811-207; 104-572-756-470-024; 104-732-601-177-448; 105-745-383-915-201; 109-172-925-539-934; 110-904-853-837-444; 112-230-768-879-062; 114-936-080-386-857; 115-699-081-749-592; 120-974-286-046-262; 121-652-742-486-910; 132-181-163-586-205; 138-038-539-768-186; 141-972-135-188-223; 143-936-693-364-687; 146-208-436-691-12X; 151-141-789-832-140; 173-086-324-900-085; 176-055-677-651-464; 180-154-858-301-189; 182-948-844-936-906; 196-032-046-212-215; 199-955-608-195-635,4,false,, -021-131-069-914-209,Cross-Cultural Learning: A Visualized Bibliometric Analysis Based on Bibliometrix from 2002 to 2021,2022-05-09,2022,journal article,Mobile Information Systems,1875905x; 1574017x,Wiley,Egypt,Jing Wang; Sihong Zhang,"With the significant increase of studies on cross-cultural learning (CCL) in the recent two decades, it is essential to conduct a systematic review of various literature and their development processes. This article is aimed at revealing research hotspots and emerging trends in CCL studies. This study adapted a visualized bibliometric approach to analyze research articles in the Cross-Cultural Learning-Internet of Things area. We extracted papers published in respected journals as the dataset. Based on bibliometrix, this study collects 1,899 records indexed in the Core Collection of Web of Science (WoS) in the domain of CCL from 2002 to 2021. The findings indicate that the number of published articles shows an apparently upward trend; the United States occupies the leading position, while the most productive journal is Computers & Education; King from Nanyang Technological University of Singapore is the most prolific author, and Nielsen ranks the first in terms of citation; cross-cultural, culture, learning, cross-cultural comparison, and cross-cultural research are found to be the most high-frequency keywords used by authors; cross-cultural projects, students and teachers, cross-cultural research, and educational technologies are the most discussed topics in this field; several notable topics related to CCL and Internet of Things. Visualization study is beneficial to track the hotspots and frontiers of CCL studies in order to effectively grasp the breakthrough points for future research. The results provide helpful information for newcomers, researchers, scholars, and practitioners to identify knowledge gaps, point out future research directions, and move this field forward.",2022,,1,11,Citation; Field (mathematics); Computer science; The Internet; Data science; Point (geometry); GRASP; Library science; World Wide Web; Geometry; Mathematics; Pure mathematics; Programming language,,,,Domestic Visiting Study Programs for Young Scholars in Colleges and Universities of China; Domestic Visiting Study Programs for Young Scholars in Colleges and Universities of China; National Social Science Foundation of China; National Social Science Foundation of China,https://downloads.hindawi.com/journals/misy/2022/7478223.pdf https://doi.org/10.1155/2022/7478223,http://dx.doi.org/10.1155/2022/7478223,,10.1155/2022/7478223,,,0,001-719-026-803-199; 007-004-937-705-003; 010-469-466-140-912; 010-495-710-613-419; 013-507-404-965-47X; 014-892-470-344-073; 015-581-328-123-841; 015-642-541-031-387; 016-737-345-422-653; 023-487-642-285-020; 026-700-343-861-680; 028-319-290-283-134; 031-936-263-647-440; 032-281-714-070-196; 033-127-677-566-360; 034-030-844-274-53X; 034-589-283-226-868; 041-156-410-847-510; 043-537-551-192-45X; 046-453-204-339-251; 047-835-359-421-313; 050-966-929-451-847; 052-557-731-366-618; 058-034-151-879-033; 059-307-864-310-979; 063-663-821-962-841; 067-410-352-311-674; 067-920-144-546-989; 083-770-002-869-706; 088-113-463-222-034; 091-424-934-482-77X; 097-759-335-124-834; 097-845-504-550-983; 098-283-084-933-13X; 099-443-018-760-089; 118-054-993-192-513; 118-488-368-187-880; 121-652-742-486-910; 126-480-782-503-045; 130-964-132-674-905; 135-418-602-334-221; 174-634-624-850-623; 186-181-696-411-60X,6,true,cc-by,gold -021-186-921-427-368,Studies related to osteosarcoma and metabolism from 1990 to 2022: A visual analysis and bibliometric study.,2023-03-06,2023,journal article,Frontiers in endocrinology,16642392,Frontiers Media SA,Switzerland,Zhuce Shao; Shuxiong Bi,"Osteosarcoma is the most common primary bone tumor, its high incidence of metastasis and poor prognosis have led to a great deal of concern for osteosarcoma. In many cancer types, metabolic processes are important for tumor growth progression, so interfering with the metabolic processes of osteosarcoma may be a therapeutic option to stall osteosarcoma progression. A key mechanism of how metabolic processes contribute to the growth and survival of various cancers, including osteosarcoma, is their ability to support tumor cell metabolism. Research related to this field is a direction of great importance and potential. However, to our knowledge, no bibliometric studies related to this field have been published, and we will fill this research gap.; Publications were retrieved on January 1, 2023 from the 1990-2022 Science Citation Index of the Web of Science Core Collection. The Bibliometrix package in R software, VOSviewer and CiteSpace software were used to analyze our research directions and to visualize global trends and hotspots in osteosarcoma and metabolism related research.; Based on the search strategy, 833 articles were finally filtered. In this area of research related to osteosarcoma metabolism, we found that China, the United States and Japan are the top 3 countries in terms of number of articles published, and the journals and institutions that have published the most research in this area are Journal of bone and mineral research, Shanghai Jiao Tong University. In addition, Baldini, Nicola, Reddy, Gs and Avnet, Sofia are the top three authors in terms of number of articles published in studies related to this field. The most popular keywords related to the field in the last 30 years are ""metabolism"" and ""expression"", which will guide the possible future directions of the field.; We used Bibliometrix, VOSviewer, and Citespace to visualize and bibliometrically analyze the current status and possible future hotspots of research in the field of osteosarcoma metabolism. Possible future hotspots in this field may focus on the related terms ""metabolism"", ""expression"", and ""migraation"".; Copyright © 2023 Shao and Bi.",14,,1144747,,Osteosarcoma; Medicine; Cancer research,bibliometrics; metabolism; osteosarcoma; trends; visualized study,Humans; China; Osteosarcoma/epidemiology; Bibliometrics; Evidence Gaps; Bone Neoplasms/epidemiology,,,https://www.frontiersin.org/articles/10.3389/fendo.2023.1144747/pdf https://doi.org/10.3389/fendo.2023.1144747,http://dx.doi.org/10.3389/fendo.2023.1144747,36950694,10.3389/fendo.2023.1144747,,PMC10025455,0,001-866-915-699-213; 002-052-422-936-00X; 002-155-203-777-16X; 002-644-986-206-79X; 003-282-838-950-93X; 003-601-811-587-160; 005-341-502-026-989; 007-940-695-828-028; 009-906-003-334-697; 010-517-919-472-551; 011-821-577-661-610; 014-366-333-423-541; 015-140-073-761-45X; 015-344-978-394-572; 016-669-722-057-478; 017-705-919-080-550; 020-913-046-530-448; 023-349-245-439-887; 026-395-112-558-483; 028-839-288-588-915; 032-491-239-017-251; 034-963-259-191-391; 045-993-333-977-461; 048-241-207-307-130; 049-187-384-490-871; 049-387-424-898-684; 064-400-499-357-900; 065-506-780-580-321; 083-058-779-937-49X; 085-001-502-383-40X; 091-711-033-455-16X; 098-719-695-326-798; 116-339-119-777-116; 122-827-252-276-011; 144-132-134-054-407; 198-453-616-697-76X,6,true,cc-by,gold -021-290-589-616-342,"Research perspectives on youth social entrepreneurship: strategies, economy, and innovation",2024-08-05,2024,journal article,Journal of Innovation and Entrepreneurship,21925372,Springer Science and Business Media LLC,,Paola Alzate; Juan F. Mejía-Giraldo; Isabella Jurado; Sara Hernandez; Alexandra Novozhenina,"Youth social enterprises have become a significant component of the global economy since the late twentieth century. With the changing world and the emergence of new economies, there is a growing demand for expanding markets and reaching new customers, making it an opportune time for young entrepreneurs to utilize their unique characteristics of creativity and drive. This study aims to conduct a systematic literature review on youth social entrepreneurship through the application of bibliometric tools and methods in order to identify needs and challenges in this field. The literature was explored using the Scopus and Web of Science (WoS) databases from 2010 to 2022. The findings were analyzed using Bibliometrix and R-Studio tools, which facilitated two methodological stages: scientific mapping and network analysis. Based on the tree metaphor, the collected documents were categorized into the root, trunk, and leaves groups. The results unveiled several research clusters, including business strategies, social entrepreneurship and capitalism, and social change and innovation, were identified. In general, the above-mentioned clusters introduce fresh approaches, suggest solutions, advocate for societal change, and enrich comprehension regarding youth-driven social enterprises. Finally, this study concludes by presenting an agenda for future research in the field.",13,1,,,Entrepreneurship; Scopus; Creativity; Social entrepreneurship; Field (mathematics); Sociology; Social science; Political science; Mathematics; MEDLINE; Pure mathematics; Law,,,,Universidad Católica Luis Amigó; Universidad Pontificia Bolivariana,https://innovation-entrepreneurship.springeropen.com/counter/pdf/10.1186/s13731-024-00410-7 https://doi.org/10.1186/s13731-024-00410-7,http://dx.doi.org/10.1186/s13731-024-00410-7,,10.1186/s13731-024-00410-7,,,0,000-295-073-843-094; 002-569-907-824-390; 002-578-897-145-531; 003-371-856-075-950; 007-814-606-432-99X; 008-849-573-450-396; 009-593-428-989-758; 010-442-924-794-711; 011-249-559-234-645; 011-477-166-087-749; 011-889-050-913-341; 015-678-211-005-826; 015-692-170-714-052; 016-645-295-742-764; 017-750-600-412-958; 019-819-098-483-480; 021-167-909-947-121; 021-975-868-805-797; 024-774-210-222-809; 025-663-010-949-485; 026-458-299-989-560; 026-591-134-281-735; 026-751-007-974-782; 028-248-497-041-049; 028-711-791-694-018; 030-562-364-899-102; 031-281-567-314-827; 032-223-837-695-174; 032-609-805-793-492; 032-634-191-515-600; 033-254-141-960-433; 034-068-190-489-454; 037-605-984-938-215; 043-219-516-358-019; 043-993-580-694-60X; 046-730-750-078-573; 046-841-674-135-16X; 049-188-438-875-465; 051-914-250-127-647; 056-113-585-807-881; 057-622-026-413-335; 059-948-933-302-578; 060-664-518-602-494; 062-529-668-286-205; 062-853-779-445-859; 063-635-695-462-206; 063-981-512-053-146; 077-446-102-740-449; 081-678-514-945-843; 091-931-643-538-426; 096-065-925-897-084; 106-945-295-200-575; 106-999-408-860-072; 108-201-041-749-702; 110-151-852-547-548; 112-528-049-287-986; 115-133-512-157-837; 119-444-441-543-186; 122-827-252-276-011; 130-458-430-956-853; 131-051-570-289-695; 132-231-595-188-06X; 135-422-416-729-184; 140-552-499-809-759; 141-953-343-806-408; 143-665-452-123-215; 145-735-894-501-491; 147-444-957-968-922; 151-082-890-683-306; 155-953-353-847-789; 174-013-112-805-456; 182-476-674-883-019; 186-820-727-372-366; 199-459-990-920-849,4,true,cc-by,gold -021-673-780-057-735,Multifunctional agriculture in the framework of the Sustainable Development Goals (SDGs): Bibliometric review,2023-11-13,2023,journal article,"Acta Universitatis Sapientiae, Agriculture and Environment",20682964; 2065748x,Universitatea Sapientia din municipiul Cluj-Napoca,,Nancy Harlet Esquivel-Marín; Leticia Myriam Sagarnaga-Villegas; Octavio Tadeo Barrera-Perales; Juan Antonio Leos-Rodríguez; José María Salas-González,"Abstract; The aim of this work was to analyse the systemic structure of multifunctional agriculture (MFA) and its nexus with sustainability through a bibliometric review of existing literature. By monitoring articles published on the Web of Science platform, a sample of 432 documents was identified. Two software packages, Bibliometrix and VOSviewer, were used to map scientific collaboration networks. The results made it possible to identify the authors, journals, and countries that had given rise to the current structure of knowledge. Four broad thematic clusters were identified: a) MFA and sustainability; b) ecosystem services and biodiversity; c) European public policies; d) governance and urban agriculture. It is concluded that despite an increase in publication rates research is concentrated in Europe, and, furthermore, there are few collaborative networks between different disciplines, suggesting that SDG17 is not being achieved.",15,1,36,51,Nexus (standard); Sustainability; Bibliometrics; Agriculture; Thematic map; Corporate governance; Sustainable development; Work (physics); Business; Biodiversity; Regional science; Knowledge management; Environmental resource management; Environmental planning; Political science; Geography; Engineering; Computer science; Library science; Ecology; Environmental science; Law; Biology; Mechanical engineering; Cartography; Archaeology; Finance; Embedded system,,,,,https://sciendo.com/pdf/10.2478/ausae-2023-0004 https://doi.org/10.2478/ausae-2023-0004,http://dx.doi.org/10.2478/ausae-2023-0004,,10.2478/ausae-2023-0004,,,0,000-058-577-203-497; 000-587-522-091-284; 001-492-104-289-911; 004-620-786-688-719; 007-009-394-286-57X; 009-649-615-894-041; 011-124-786-806-392; 011-738-245-228-346; 011-955-708-643-126; 012-027-537-118-881; 013-507-404-965-47X; 015-898-917-078-597; 016-397-705-925-724; 017-295-429-481-985; 017-866-789-755-165; 019-995-445-052-03X; 020-011-254-440-110; 022-038-564-851-452; 024-783-966-833-508; 026-370-779-625-508; 027-406-540-345-844; 028-203-920-933-230; 032-517-326-134-723; 034-249-481-167-634; 035-437-409-983-869; 037-605-125-409-93X; 037-989-280-310-687; 039-491-120-499-550; 043-021-589-133-538; 043-518-100-308-018; 047-929-146-657-047; 051-649-151-549-102; 063-297-141-983-537; 066-576-525-112-977; 071-189-109-974-878; 074-851-718-319-02X; 075-020-574-415-918; 082-038-722-150-421; 086-693-510-804-813; 087-252-612-603-513; 098-721-626-780-017; 099-541-856-823-527; 105-694-948-517-183; 112-130-829-623-127; 127-264-583-496-962; 130-602-202-936-694; 131-402-638-973-621; 146-796-877-715-194; 152-036-331-324-39X,1,true,cc-by-nc-nd,gold -022-185-218-438-446,Bibliometric analysis using Bibliometrix an R Package,2018-11-09,2018,,,,,,Hamid Darvish,,,,,,Software engineering; R package; Open source software; Bibliometric analysis; Computer science,,,,,https://digital.library.unt.edu/ark:/67531/metadc1393794/ https://digital.library.unt.edu/ark:/67531/metadc1393794/m2/1/high_res_d/Experience_Report_Darvish.pdf,https://digital.library.unt.edu/ark:/67531/metadc1393794/,,,3013570731,,0,,1,false,, -022-203-119-300-720,"Comments on ""Research hotspots and trends of Kinesio Taping from 2011 to 2020: a bibliometric analysis"" by Kehu, Yang et al., DOI: 10.1007/s11356-022-22,300-9.",2023-04-13,2023,letter,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Waseem Hassan; Mohamad Fawzi Mahomoodally,,30,32,79551,79552,Ecotoxicology; Geography; Biology; Toxicology,Bibliometric Analysis; Kinesio Taping; Scopus,Athletic Tape; Bibliometrics,,,,http://dx.doi.org/10.1007/s11356-023-26864-y,37055692,10.1007/s11356-023-26864-y,,,0,109-693-409-736-716,1,false,, -022-538-615-480-884,Penguatan Penelitian Persaingan di Bidang Industri : Tinjauan Bibliometrix,2023-11-25,2023,journal article,Co-Value Jurnal Ekonomi Koperasi dan kewirausahaan,28098862; 20863306,Green Publisher,,Jafar Amir; Besar Agung M,"Ketika peneliti akan melakukan penelitian dengan topik Persaingan industri, maka membutuhkan panduan dalam pencarian referensi dan variable yang relevan. Penelitian ini mengungkapkan hasil analisa Bibliomatrix terhadap artikel dengan klasifikasi ""Persaingan"" DAN ""Industri"" yang diterbitkan pada rentang waktu tahun 2019 sampai dengan 2023. Hasilnya menunjukkan bahwa dari 1065 artikel yang diterbitkan, 564 artikel dari Cina dan penulis yang paling relevan adalah Wang, Y. Terungkap juga Journal yang paling relevan adalah Jurnal Energi dengan 63 Artikel. Kutipan rata-rata geografis mengungkapkan bahwa penulis dari Inggris dikutip paling serig, dengan 1759 kutipan, dengan rata-rata 20,5 kutipan / artikel. Penelitian ini juga mengungkapkan bahwa variable pengembangan berkelanjutan adalah topik yang paling direkomendasikan untuk diteliti lebih lanjut. Dengan panduan tersebut, peneliti akan mudah mendapatkan referensi dan variable penelitian yang relevan. Sehingga dapat menghasilkan penelitian yang mempunyai kontribusi besar dan relevan. Hal ini sangat dibutuhkan oleh praktisi dunia Industri.",14,6,,,Business,,,,,,http://dx.doi.org/10.59188/covalue.v14i6.3835,,10.59188/covalue.v14i6.3835,,,0,,0,false,, -022-562-433-560-250,Bibliometric analysis of the Japan-Russia scientific cooperation networks using R bibliometrix,2024-08-26,2024,journal article,"Journal of Infrastructure, Policy and Development",25727931; 25727923,EnPress Publisher,,Boris Boiarskii; Anna Lyude; Anastasiia Boiarskaia; Norikuni Ohtake; Hideo Hasegawa,"Bibliometric analysis is a commonly used tool to assess scientific collaborations within the researchers, community, institution, regions and countries. The analysis of publication records can provide a wealth of information about scientific collaboration, including the number of publications, the impact of the publications, and the areas of research where collaborations are most common. By providing detailed information on the patterns and trends in scientific collaboration, these tools can help to inform policy decisions and promote the development of effective strategies to support and enhance scientific collaborations between countries. This study aimed to analyze and visualize the scientific collaboration between Japan and Russia, using bibliometric analysis of collaborative publications from the Web of Science (WoS) database. The analysis utilized the bibliometrix package within the R statistical program. The analysis covered a period of two decades, from 2000 to 2021. The results showed a slight decrease in co-authored publications, with an annual growth rate of −1.26%. The keywords and thematic trends analysis confirmed that physics is the most co-authored field between the two countries. The study also analyzed the collaboration network and research funding sources. Overall, the study provides valuable insights into the current state of scientific collaboration between Japan and Russia. The study also highlights the importance of research funding sources in promoting and sustaining scientific cooperation between countries. The analysis suggests that more efforts in government funding are needed to increase collaboration between the two countries in various fields.",8,8,6155,6155,Regional science; Political science; Geography,,,,,,http://dx.doi.org/10.24294/jipd.v8i8.6155,,10.24294/jipd.v8i8.6155,,,0,,1,true,,gold -022-667-098-917-013,Intelligent mine safety risk based on knowledge graph: hotspots and frontiers.,2024-02-22,2024,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Dongping Shi; Zhong Chen; Xiaoqiang Zhang; Chengyu Xie,,31,14,20699,20713,Upgrade; Visualization; Computer science; Field (mathematics); Data science; Risk analysis (engineering); Engineering; Construction engineering; Business; Data mining; Mathematics; Pure mathematics; Operating system,Bibliometric analysis; Intelligent mine; Risk; Safety; Visualization,"Humans; Pattern Recognition, Automated; Environment; Head; Knowledge; Technology",,Natural Science Foundation of Hunan Province (2021JJ40538); Scientific Research Foundation of Hunan Provincial Education Department (21B0133); Foundation of Key Laboratory of Large Structure Health Monitoring and Control in Hebei Province (KLLSHMC2104),,http://dx.doi.org/10.1007/s11356-024-32561-1,38388977,10.1007/s11356-024-32561-1,,,0,001-928-135-276-173; 002-359-522-563-809; 003-367-921-510-938; 004-220-130-362-81X; 007-855-438-988-446; 009-016-235-518-124; 009-126-260-274-915; 011-062-855-064-652; 012-908-961-491-183; 017-170-473-029-751; 017-750-600-412-958; 018-038-861-704-104; 018-080-761-610-353; 019-436-700-035-755; 021-410-510-232-332; 024-456-727-627-450; 024-743-483-081-00X; 026-589-713-990-429; 027-495-891-012-803; 030-472-677-891-938; 030-504-434-962-256; 031-468-652-585-461; 031-755-098-018-559; 033-264-777-330-938; 036-656-168-693-890; 038-667-650-012-009; 039-742-165-402-023; 041-023-615-414-381; 042-125-421-236-891; 043-302-946-650-711; 043-508-452-922-880; 045-451-228-149-799; 045-737-890-372-358; 046-325-391-721-360; 046-543-775-924-832; 051-405-161-511-502; 053-469-784-754-40X; 062-068-163-079-850; 067-821-824-941-057; 085-593-933-615-85X; 088-051-322-939-137; 093-535-016-214-762; 093-877-954-043-517; 096-281-994-585-558; 100-651-161-847-961; 102-192-485-818-107; 102-953-532-084-809; 105-700-006-981-810; 113-438-999-633-608; 114-085-326-139-774; 123-023-098-068-427; 125-203-176-143-834; 131-095-083-632-032; 138-945-134-042-618; 139-066-649-264-637; 139-358-789-997-271; 142-245-679-542-02X; 143-556-672-291-357; 150-883-605-537-515; 160-488-543-572-691; 164-780-072-243-448; 169-176-534-671-860; 177-255-327-120-295; 178-150-534-305-001; 179-031-856-800-376; 187-165-655-584-324; 189-741-533-151-243; 193-579-420-990-827,3,false,, -022-730-666-745-846,Unraveling the origins of construction rework: a holistic bibliometric analysis and exploration of causative factors,2024-05-31,2024,journal article,Open House International,01682601; 26339838,Emerald,Netherlands,Gulden Gumusburun Ayalp; Eda Nur Erdem,"PurposeConstruction experts acknowledge the adverse effects of rework on project performance. However, the limited understanding of its underlying causes remains a significant challenge. Therefore, this study aimed to thoroughly investigate the sources of construction rework.Design/methodology/approachA mixed review using bibliometric analysis as a quantitative method and content analysis as a qualitative method was performed to understand the current knowledge in the field. The Web of Science (WoS) was selected for its comprehensive collection of major research articles and integrated analytical tools for generating representative data. The study involved an extensive bibliometric analysis of 107 journal articles on rework causes from 1991 to 2023. RStudio Bibliometrix, an R statistical programming package, was used to analyze rework origins. This method involved mapping the research landscape, identifying research gaps and analyzing emerging trends.FindingsThe causes of rework can be classified into three main clusters: human- and contractual-based rework causes, design-, quality- and project management-based rework causes and organizational-based rework causes.Originality/valueAlthough several studies have addressed rework causes from various perspectives and methods, the topic has not been investigated holistically. This study is the first to leverage the quantitative and qualitative analytical capabilities of the RStudio Bibliometrix package. Innovative approaches, including the use of metrics, such as the h-index, thematic mapping and trend topic analysis, were employed for a comprehensive understanding of rework causes.",50,1,65,97,Rework; Thematic analysis; Originality; Computer science; Leverage (statistics); Process management; Qualitative research; Data science; Knowledge management; Engineering; Sociology; Artificial intelligence; Embedded system; Social science,,,,,,http://dx.doi.org/10.1108/ohi-10-2023-0235,,10.1108/ohi-10-2023-0235,,,0,000-180-294-435-57X; 000-632-377-268-396; 001-347-319-058-538; 001-526-847-963-586; 004-668-918-587-489; 005-879-961-190-221; 011-378-688-618-232; 011-943-286-211-084; 012-693-446-254-356; 012-970-314-086-162; 013-507-404-965-47X; 013-524-854-219-241; 013-723-005-056-056; 015-240-007-283-03X; 016-226-486-135-880; 016-293-547-479-557; 017-059-795-098-834; 018-709-805-020-132; 024-591-990-672-234; 025-470-273-142-228; 025-554-508-375-842; 026-022-345-774-468; 026-441-794-211-886; 030-070-985-228-781; 030-262-105-331-569; 035-292-136-057-557; 035-563-802-717-804; 037-014-075-394-156; 037-079-003-167-429; 037-461-395-479-989; 037-838-889-722-069; 039-480-019-931-86X; 040-175-503-127-245; 040-605-678-052-385; 041-595-669-381-769; 041-833-054-937-573; 043-177-894-454-013; 043-298-923-923-060; 044-182-955-499-227; 044-528-564-618-933; 048-789-062-787-498; 049-394-541-782-117; 049-961-938-336-287; 052-461-334-451-150; 053-099-384-393-590; 053-387-017-445-674; 056-379-646-805-758; 062-522-273-500-252; 063-326-411-344-154; 063-370-667-539-471; 063-840-841-023-600; 064-899-859-452-879; 067-903-000-070-577; 076-456-640-963-853; 078-268-130-959-859; 081-267-179-565-15X; 081-547-256-855-879; 082-752-302-880-063; 089-238-200-383-798; 091-848-577-995-962; 094-666-886-106-147; 096-879-808-529-373; 099-757-835-827-150; 099-797-087-801-081; 101-804-190-760-161; 102-694-788-795-301; 104-919-753-218-202; 108-033-960-943-565; 110-287-884-037-879; 110-419-297-754-04X; 121-652-742-486-910; 121-691-859-457-883; 123-104-666-242-484; 125-304-559-435-255; 132-432-570-959-535; 136-519-072-747-879; 138-450-373-251-703; 147-262-381-757-796; 151-833-442-716-834; 157-802-716-965-990; 160-855-624-324-018; 170-054-826-549-963; 184-646-281-957-373; 187-336-832-886-547,1,false,, -023-215-068-271-513,"RESEARCH ON CAREER MANAGEMENT AND SUCCESSION PLANNING IN THE FIELD OF BUSINESS, MANAGEMENT, AND ACCOUNTING: A BIBLIOMETRIC PERSPECTIVE",2024-06-13,2024,journal article,International Journal of Entrepreneurship and Management Practices,26008750,Global Academic Excellence (M) Sdn Bhd,,Ummu Athilia Kamal; Muhammad Aiman Arifin; Razlina Razali,"In recent years, scientific publications on the topic of career management and succession planning (CMSP) within the field of business, management, and accounting have grown significantly. However, a comprehensive bibliometric review of CMSP research is lacking. This study aimed to fill that gap by examining 50 years of CMSP research using the Scopus database, VOS Viewer, and the Bibliometrix R-package. The analysis of 283 articles has uncovered that previous studies on CMSP have mainly focused on family firms, organisational career management, and family businesses. This pioneering study offers valuable insights to current scholars, future researchers, and practitioners by shedding light on CMSP’s evolution and by suggesting potential avenues for further research.",7,25,17,29,Perspective (graphical); Management accounting; Succession planning; Accounting; Field (mathematics); Business; Ecological succession; Management; Computer science; Economics; Finance; Mathematics; Ecology; Artificial intelligence; Pure mathematics; Biology,,,,,,http://dx.doi.org/10.35631/ijemp.725003,,10.35631/ijemp.725003,,,0,,0,true,,gold -023-236-577-966-527,Blockchain as an enabling technology in the COVID-19 pandemic: a systematic review.,2021-09-06,2021,journal article,Health and technology,21907188; 21907196,Springer Science and Business Media LLC,Germany,Pedro Henrique Ribeiro Botene; Anibal Tavares de Azevedo; Paulo Sérgio de Arruda Ignácio,"The impacts caused by the unprecedented transmission of COVID-19 have given rise to new challenges that are shaking the structures of humanity. Several enabling technologies are currently being used as key strategies in creating improvements and responses to the difficulties created by the pandemic and blockchain is one of these solution proposals. Within this scenario, this work aims to study and analyze how the blockchain technology can help in the struggle against the COVID-19 pandemic through a systematic review of the literature. Although the study is limited by the moment when the crisis is still in progress, the results show that it is clear that the adoption of the blockchain can effectively help in the fight against the coronavirus, considering that the main features of the blockchain can support the successful implementation of many use cases. This paper has the role of assisting academics and professionals in identifying the application focus of the blockchain, as well as showing the main opportunities and challenges and the relevance of the subject to the current context of the pandemic.",11,6,1,14,Risk analysis (engineering); Work (electrical); Key (cryptography); Blockchain; Context (language use); Coronavirus disease 2019 (COVID-19); Use case; Computer science; Relevance (information retrieval); Pandemic,Blockchain; COVID-19; Distributed Ledger; Systematic Review,,,,https://link.springer.com/article/10.1007/s12553-021-00593-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421063 https://link.springer.com/content/pdf/10.1007/s12553-021-00593-z.pdf,http://dx.doi.org/10.1007/s12553-021-00593-z,34513552,10.1007/s12553-021-00593-z,3196487281,PMC8421063,0,001-780-810-658-450; 007-893-129-905-843; 009-045-593-399-690; 012-399-200-811-856; 012-608-157-617-641; 013-507-404-965-47X; 021-854-525-740-716; 024-726-367-463-241; 027-668-521-171-586; 029-079-277-327-741; 029-338-959-431-806; 032-478-826-024-185; 033-590-646-771-294; 034-545-974-804-95X; 035-881-177-484-921; 038-198-333-238-419; 038-806-445-494-018; 040-313-599-661-145; 041-501-895-247-568; 044-269-094-788-079; 045-804-685-856-545; 047-505-632-961-58X; 048-322-307-535-215; 054-842-941-091-224; 063-453-765-093-104; 073-252-000-645-976; 074-207-772-471-885; 075-964-096-154-116; 076-702-008-816-48X; 078-830-760-327-210; 079-601-725-215-923; 079-792-339-934-246; 082-230-526-203-75X; 083-275-795-865-394; 085-314-492-915-19X; 089-513-349-049-580; 092-477-003-190-088; 094-073-481-272-354; 107-628-650-729-797; 115-685-910-686-190; 129-366-171-970-63X; 130-041-936-424-092; 131-928-829-488-422; 137-519-888-164-867; 155-565-532-977-816; 159-732-660-809-340; 166-493-462-848-515; 186-081-237-537-037,11,true,,green -023-239-826-520-248,"Use of multicriteria decision aid methods in the context of sustainable innovations: bibliometrics, applications and trends",2021-04-22,2021,journal article,Environment Systems and Decisions,21945403; 21945411,Springer Science and Business Media LLC,United States,Jamile Eleutério Delesposte; Luís Alberto Duncan Rangel; Marcelo Jasmim Meiriño; Ramon Baptista Narcizo; André Armando Mendonça de Alencar Junior,,41,4,501,522,,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,,http://dx.doi.org/10.1007/s10669-021-09814-2,,10.1007/s10669-021-09814-2,,,0,000-027-854-280-334; 001-084-320-273-831; 002-052-422-936-00X; 002-111-864-790-877; 003-550-080-967-321; 003-683-118-762-153; 005-633-968-742-981; 006-444-460-295-619; 007-482-418-341-574; 007-706-130-461-622; 008-346-181-288-807; 010-931-702-311-654; 011-896-264-966-479; 013-507-404-965-47X; 013-558-194-366-638; 014-340-221-430-741; 016-008-294-807-528; 017-750-600-412-958; 020-681-074-615-385; 022-304-653-352-160; 022-542-172-103-554; 023-036-388-175-594; 023-260-815-021-028; 024-388-806-468-644; 024-408-522-792-35X; 024-594-715-748-277; 025-769-722-271-663; 026-123-669-760-700; 026-397-825-025-504; 028-405-228-114-357; 030-162-942-660-767; 030-412-281-755-572; 031-701-151-113-499; 032-766-671-840-212; 034-145-218-792-807; 034-320-827-119-525; 034-542-572-302-160; 036-161-872-547-032; 039-749-389-865-096; 043-151-821-380-302; 043-296-182-294-930; 043-735-687-593-436; 044-791-345-910-81X; 047-134-478-431-993; 049-768-019-209-709; 054-818-565-070-154; 056-986-751-110-258; 059-488-544-420-146; 062-862-505-801-929; 067-523-053-978-920; 069-737-545-350-909; 072-610-779-757-007; 074-003-296-866-768; 075-939-282-420-567; 076-835-568-819-485; 080-019-263-819-504; 080-049-740-463-713; 080-762-641-842-666; 081-532-972-369-677; 083-202-108-164-16X; 083-227-128-606-683; 084-360-342-840-840; 086-566-158-989-73X; 088-309-624-051-024; 088-963-097-096-998; 089-440-755-213-337; 090-997-793-709-839; 095-581-341-386-816; 095-852-096-688-360; 097-268-126-367-34X; 098-252-844-714-772; 107-866-341-850-677; 109-974-366-952-574; 111-215-741-447-161; 113-182-287-467-481; 120-240-257-392-518; 120-974-286-046-262; 121-091-499-243-136; 121-652-742-486-910; 123-005-320-899-178; 124-542-603-127-901; 127-233-002-232-685; 132-727-710-709-633; 140-483-286-140-426; 141-326-217-499-897; 142-445-839-185-620; 146-201-942-972-811; 146-982-478-378-185; 161-888-066-873-49X; 165-673-606-818-297; 168-392-276-375-62X; 172-170-822-440-937; 177-060-398-152-016; 190-656-831-899-216; 192-323-382-937-148; 192-389-272-784-584,7,false,, -023-286-487-782-877,Tendencias investigativas de la fragmentación urbana en América Latina y el Caribe: una revisión sistemática de literatura,2023-06-14,2023,journal article,Revista Venezolana de Gerencia,24779423; 13159984,Universidad del Zulia,Venezuela,Natalia Mejía Franco; Ciro Alfonso Serna Mendoza; Miroslawa Czerny,"El crecimiento urbano incontrolado en América Latina y el Caribe ha dado lugar a mayor presencia de habitantes en barrios pobres, infraestructuras y servicios inadecuados y sobrecargados, dando lugar a ciudades fragmentadas. La presente revisión utilizó técnicas de cartografía científica y sistemática de investigación para examinar 1486 documentos indexados en Scopus® sobre el desarrollo de la fragmentación urbana en América Latina y el Caribe; para el análisis de la información se utilizó Bibliometrix® y VOSviwer® para facilitar la comprensión de los datos. Los objetivos de la revisión son documentar el tamaño, el crecimiento y la distribución de esta literatura en la región, identificar sus principales autores y fuentes de publicación y resaltar la estructura intelectual emergente. Como parte de los resultados, se identifica que, a pesar de la urgencia de documentar y abordar los retos de la fragmentación urbana, se encontró que la mayoría de los estudios son de autoría procedente de solo ciertos países de la región. La revisión aporta tendencias investigativas para que se desarrollen estudios que favorezcan el desarrollo y las discusiones futuras en relación con su impacto sobre los sistemas socio-ecológicos, su relación con el desarrollo sustentable, y su incidencia con enfoque diferencial poblacional.",28,103,1257,1277,Humanities; Political science; Geography; Art,,,,,https://zenodo.org/records/8160879/files/ART21.pdf https://zenodo.org/record/8160879 https://dialnet.unirioja.es/descarga/articulo/9000845.pdf https://dialnet.unirioja.es/servlet/oaiart?codigo=9000845,http://dx.doi.org/10.52080/rvgluz.28.103.22,,10.52080/rvgluz.28.103.22,,,0,001-375-032-648-790; 008-476-769-613-602; 009-154-576-048-55X; 010-040-969-399-975; 011-668-134-336-335; 019-129-716-649-671; 020-327-786-458-590; 025-231-763-021-295; 026-236-767-521-704; 027-950-722-365-036; 032-907-270-483-791; 034-702-120-144-00X; 035-127-135-956-113; 040-374-250-228-583; 043-012-967-623-653; 043-100-049-743-795; 044-553-310-082-379; 046-644-786-779-59X; 046-973-781-650-962; 048-682-108-606-200; 052-119-538-827-785; 060-781-295-367-45X; 060-835-015-311-568; 062-755-101-780-216; 066-828-345-518-45X; 068-923-690-108-812; 069-643-321-175-868; 069-974-132-717-505; 073-593-280-545-931; 082-361-611-529-295; 083-229-348-539-522; 084-505-118-672-672; 084-774-972-294-565; 085-300-287-100-525; 095-956-195-446-099; 096-268-376-389-465; 098-193-895-133-970; 101-318-181-583-550; 104-314-880-519-866; 112-988-935-278-862; 121-942-863-513-386; 123-521-962-634-500; 129-262-074-969-921; 131-244-207-724-470; 131-585-461-167-652; 136-006-908-059-424; 138-253-603-117-436; 139-909-548-432-470; 150-968-080-362-179; 165-987-118-354-317; 177-214-997-033-413; 181-510-097-451-602; 193-612-623-774-341,1,true,cc-by-nc-sa,gold -023-407-891-655-720,Measuring Research Productivity of Universities with Centre with Potential for Excellence in Particular Area (CPEPA) status in Karnataka State,2021-08-26,2021,journal article,DESIDOC Journal of Library & Information Technology,09764658; 09740643,Defence Scientific Information and Documentation Centre,India,Mallikarjun Kappi; M. Chaman Sab; B. S. Biradar,"This paper aims to track the research output of the ‘Universities with CPEPA status in Karnataka’ during 2010–2019 as considering the Web of Science database. The Karnatak University, Dharwad, Bangalore University, Bangalore, and the University of Mysore, Mysore have been selected. A total of 8952 documents have been retrieved consisting of journal articles, conference papers, book chapters, so on. A steady increase in research output has been observed. The University of Mysore (UMM) has the largest number of publications. The study shows that multi-authored papers have greater research influence in receiving citations. The study found the most productive authors and their production impacts in terms of the number of citations (ACPP) and also identified the most occurred keywords and journals used to publishing the research results. For visualisation purposes, VOSviewer and Bibliometrix R Package were used.",41,5,358,367,Publishing; Library science; Productivity; Geography; Excellence; R package; Scientometrics; Scopus,,,,,https://publications.drdo.gov.in/ojs/index.php/djlit/article/view/16507,http://dx.doi.org/10.14429/djlit.41.5.16507,,10.14429/djlit.41.5.16507,3196842479,,0,,1,true,cc-by-nc-nd,gold -023-417-324-459-263,Mapping the Cause-Related Marketing (CRM) field: document co-citation and bibliographic coupling approach,2022-11-05,2022,journal article,International Review on Public and Nonprofit Marketing,18651984; 18651992,Springer Science and Business Media LLC,Germany,Tejaswi Patil; Zillur Rahman,,20,2,491,520,Bibliographic coupling; Scopus; Marketing; Cluster (spacecraft); Database marketing; Theme (computing); Citation; Business; Customer relationship management; Computer science; Relationship marketing; Marketing management; Political science; World Wide Web; MEDLINE; Law; Programming language,,,,,,http://dx.doi.org/10.1007/s12208-022-00347-1,,10.1007/s12208-022-00347-1,,,0,000-558-208-762-278; 001-007-146-564-203; 002-052-422-936-00X; 002-283-433-335-54X; 003-058-216-451-849; 003-229-861-202-363; 003-350-233-511-987; 003-550-641-746-941; 004-146-899-253-679; 004-810-769-800-411; 005-700-725-753-042; 006-254-691-025-301; 006-667-896-993-897; 007-174-255-486-829; 007-485-504-465-112; 007-898-350-109-582; 009-575-398-666-624; 010-854-534-444-434; 012-038-152-711-16X; 013-507-404-965-47X; 013-781-507-563-010; 014-092-563-907-466; 014-152-369-086-221; 015-773-267-074-703; 016-272-391-714-297; 016-568-570-436-870; 016-687-909-814-255; 017-144-704-283-871; 017-750-600-412-958; 018-606-075-915-716; 018-929-265-782-607; 019-677-394-396-460; 019-697-380-222-302; 019-738-048-708-739; 020-773-550-003-936; 023-123-216-363-957; 023-927-221-065-800; 023-944-640-238-248; 024-445-387-691-54X; 024-524-317-273-663; 027-469-718-851-591; 027-716-768-108-304; 028-513-151-138-964; 028-764-385-946-864; 029-586-259-881-227; 030-803-372-834-004; 031-255-317-376-25X; 032-226-726-401-253; 035-277-708-110-996; 035-782-090-260-323; 036-627-126-357-634; 037-474-783-441-942; 037-479-522-981-871; 038-281-762-539-313; 038-287-528-914-91X; 042-198-912-760-329; 043-107-093-223-107; 043-488-502-843-561; 043-605-651-281-566; 044-686-753-444-18X; 045-974-517-175-371; 046-796-139-452-69X; 046-992-864-415-70X; 047-084-373-523-100; 047-175-936-123-199; 049-466-768-340-647; 050-609-067-982-963; 054-818-565-070-154; 056-126-178-605-45X; 057-898-407-859-899; 061-389-881-332-049; 061-907-032-205-149; 062-259-542-892-640; 062-481-973-782-66X; 063-539-513-284-315; 063-874-171-997-283; 063-983-853-006-486; 064-063-708-035-20X; 066-323-431-350-16X; 068-265-395-001-914; 069-171-279-552-128; 070-756-828-609-22X; 072-896-130-914-377; 074-589-917-476-692; 075-170-238-988-964; 077-090-621-219-984; 079-111-620-646-610; 079-843-485-383-267; 080-703-586-964-053; 081-579-693-159-480; 083-141-409-127-163; 083-233-429-885-517; 086-881-079-233-635; 087-264-081-681-958; 088-219-401-094-247; 088-535-378-885-781; 088-579-168-794-122; 090-545-821-294-574; 091-172-404-265-083; 092-331-581-754-859; 093-362-673-911-75X; 094-308-341-507-012; 095-628-637-197-729; 098-984-500-762-029; 099-026-353-525-10X; 102-520-995-329-549; 102-559-603-225-328; 104-617-181-886-964; 106-824-173-416-545; 107-353-157-595-895; 108-890-126-050-163; 110-994-862-224-393; 112-086-245-979-159; 112-634-769-296-02X; 112-880-239-123-088; 114-240-865-218-030; 117-274-976-629-160; 117-404-452-177-864; 122-049-786-547-56X; 122-408-558-844-564; 124-187-446-936-209; 124-187-743-925-055; 125-476-469-867-426; 127-384-572-160-036; 127-728-291-438-448; 130-337-826-075-162; 134-690-507-205-989; 137-173-960-162-28X; 139-101-567-335-455; 139-897-686-315-859; 140-880-535-864-601; 141-302-242-630-109; 143-936-693-364-687; 145-430-864-980-383; 146-267-791-584-388; 146-860-615-945-17X; 149-783-387-615-170; 150-620-050-692-540; 150-843-511-104-827; 151-317-840-009-376; 154-054-575-849-696; 156-305-085-039-099; 158-200-405-885-190; 158-880-354-325-805; 160-171-583-975-975; 163-143-294-532-60X; 163-162-773-085-118; 169-712-892-543-005; 173-718-612-352-995; 179-061-800-547-559; 180-723-872-169-839; 185-050-475-065-604; 185-684-138-457-046,7,false,, -023-538-079-452-690,EVASÃO NO ENSINO SUPERIOR: UM MAPEAMENTO DA PRODUÇÃO CIENTÍFICA MUNDIAL BASEADO NA WEB OF SCIENCE,2025-06-19,2025,journal article,LUMEN ET VIRTUS,21772789,Seven Events,,Juliana Mara Pereira da Cunha; Saulo Cardoso Maia,"A evasão no ensino superior é um problema crescente e tem atraído atenção de pesquisadores mundialmente. O objetivo deste trabalho é mapear a produção científica sobre o tema por meio de um estudo bibliométrico com dados da Web of Science. As buscas foram feitas com termos relacionados à evasão na graduação. Os artigos encontrados foram analisados com gráficos, redes e tabelas, principalmente com o pacote Bibliometrix. Os resultados apresentam um inventário das publicações com informações úteis para pesquisadores da área. O estudo traz dados sistematizados que fomentam a pesquisa sobre evasão acadêmica no Brasil e no mundo, contribuindo para o conhecimento do tema e apoio a políticas públicas.",16,49,7020,7044,,,,,,,http://dx.doi.org/10.56238/levv16n49-061,,10.56238/levv16n49-061,,,0,,0,true,cc-by-nc,gold -023-836-033-817-354,The published role of artificial intelligence in drug discovery and development: a bibliometric and social network analysis from 1990 to 2023.,2025-05-08,2025,journal article,Journal of cheminformatics,17582946,Springer Science and Business Media LLC,United Kingdom,Murat Koçak; Zafer Akçalı,"Today, drug discovery and development is one of the fields where Artificial Intelligence (AI) is used extensively. Therefore, this study aims to systematically analyze the scientific literature on the application of AI in drug discovery and development to understand the evolution, trends, and key contributors within this rapidly growing field. By leveraging various bibliometric indicators and visualization techniques, we seek to explore the growth patterns, influential authors and institutions, collaboration networks, and emerging research trends within this domain. Bibliometric and network analysis methods (co-occurrence, co-authorship, and collaboration, etc.) were used to achieve this goal. Bibliometric visualization tools such as Bibliometrix R package software, VOSviewer, and Litmaps were used for comprehensive data analysis. Scientific publications on AI in drug discovery and development were retrieved from the Web of Science Core Collection (WoS CC) database covering 1990-2023. In addition to visualization programs, the InCites database was also used for analysis and visualization. A total of 4059 scientific publications written by 13,932 authors and published in 1071 journals were included in the analysis. The results reveal that the most prolific authors are Ekins (n = 67), Schneider (n = 52), Hou Tj (n = 43), and Cao Ds (n = 34), while the most active institutions are the ""Chinese Academy of Science"" and ""University of California."" The leading scientific journals are ""Journal of Chemical Information and Modelling,"" ""Briefings in Bioinformatics,"" and ""Journal of Cheminformatics."" The most frequently used author keywords include ""protein folding,"" ""QSAR,"" ""gene expression data,"" ""coronavirus,"" and ""genome rearrangement."" The average number of citations per scientific publication is 28.62, indicating a high impact of research in this field. A significant increase in publications was observed after 2014, with a peak in 2022, followed by a slight decline. International collaboration accounts for 28.06% of the publications, with the USA and China leading in both productivity and influence. The study also identifies key funding organizations, such as the National Natural Science Foundation of China (NSFC) and the United States Department of Health & Human Services, which have significantly supported advancements in this field. In conclusion, this study highlights the transformative role of AI in drug discovery and development, showcasing its potential to accelerate innovation and improve efficiency. The findings provide valuable insights into the current state of research, emerging trends, and future directions, offering a roadmap for researchers, industry professionals, and policymakers to further explore and leverage AI technologies in this domain.Scientific contributionThis study provides a comprehensive bibliometric analysis of 4,059 scientific publications (1990-2023) to map the evolution, trends, and key contributors in AI-driven drug discovery, identifying prolific authors (e.g., Ekins, Schneider), leading institutions (e.g., Chinese Academy of Sciences, University of California), and high-impact journals (Journal of Chemical Information and Modelling). It reveals critical collaboration patterns (28.06% international co-authorships), dominant funding sources (e.g., NSFC, NIH), and emerging research hotspots (e.g., protein folding, QSAR, coronavirus), while highlighting the transformative role of deep learning post-2014. By synthesizing these insights, the study offers a strategic roadmap for researchers and policymakers to optimize AI applications in drug development, addressing both current challenges and future opportunities in the field.",17,1,71,,Drug discovery; Data science; Computer science; Social network analysis; Bibliometrics; Library science; World Wide Web; Bioinformatics; Social media; Biology,Artificial intelligence (AI); Bibliometric analysis; Drug development; Drug discovery; Network analysis; Scientific publications,,,,,http://dx.doi.org/10.1186/s13321-025-00988-4,40341055,10.1186/s13321-025-00988-4,,PMC12063294,0,000-452-908-115-500; 002-052-422-936-00X; 003-615-531-300-37X; 003-921-849-886-855; 005-072-052-761-608; 011-585-166-949-941; 013-507-404-965-47X; 013-524-854-219-241; 014-772-466-372-040; 015-004-974-426-708; 018-893-501-990-992; 026-297-351-248-176; 028-832-372-306-966; 034-097-696-904-072; 038-439-947-761-188; 044-523-432-982-677; 046-992-864-415-70X; 057-284-874-077-080; 058-252-517-480-162; 059-149-073-001-124; 059-505-525-211-201; 064-354-018-228-661; 100-445-029-445-191; 107-518-655-388-824; 123-202-581-406-928; 172-818-505-203-080; 198-678-746-883-912,1,true,"CC BY, CC0",gold -023-838-403-119-991,Status and dimensions of research on coopetition in wine tourism,2025-02-18,2025,journal article,Rural Society,10371656; 22040536,Taylor and Francis Ltd.,United Kingdom,Kettrin Farias Bem Maracajá; Adriana Fumi Chim-Miki; Rui Costa,"This research aims to identify the evolution, trends, core themes, and dimensions of coopetition in wine tourism research. We analysed 201 articles published on the Web of Science based on social network analysis and bibliometric analysis supported by Bibliometrix, R, and VOSviewer software. The results highlight trends focusing on coopetition, co-creation, sustainability, rural tourism, and wine routes to promote local development and synergies between old industries, winemakers, and tourism. Trending topics contribute to understanding the perception of the benefits and challenges of involving wineries in wine tourism. The review shows evidence of a coopetitive mindset in the wine industry, linked to a profitable aspect vis-à-vis the tourism chain, in which competition is intrinsic behaviour. Coopetition, however, remains emergent and unintentional in wine tourism. The winescape provides accelerator variables for coopetition, a new paradigm and a vital strategy.",,,1,23,Coopetition; Wine; Tourism; Business; Project commissioning; Economic geography; Marketing; Publishing; Advertising; Regional science; Sociology; Geography; Political science; Economics; Market economy; Art; Archaeology; Law; Visual arts; Incentive,,,,,,,,,,,0,,0,false,, -024-071-326-280-903,Policy and Governance Publications in Southeast Asia During The Period 2012–2022 : A Bibliometric Analysis,2024-07-18,2024,journal article,Jurnal Manajemen Pelayanan Publik,25811878; 25809970,Universitas Padjadjaran,,Nina Karlina; Budiman Rusli; Candradewini Candradewini; Dedi Sukarno; Riki Satia Muharam,"The purpose of this investigation is to determine which issue in Policy and Governance Publications in Southeast Asia During The Period 2012–2022 is currently trending. To analyze the data, we extracted it from the Scopus database and ran it using R software's Bibliometrix program, which was then imported into VOSviewer. According to criteria derived from citation analysis, we have identified the most important papers, journals, authors, countries, and affiliations in Southeast Asia. Indonesia has published the greatest number of contributions, followed by Malaysia and Thailand, according to the country's scientific productivity. However, even though keywords and phrases are likely to be the most relevant subjects and findings of the research, it is possible that some of the main patterns and concerns that have been covered in the entire text are not well represented in our investigation. In addition, future studies should examine relevant research clusters for developing patterns in Bibliometric in order to provide scientific information.",8,2,645,664,Period (music); Corporate governance; Bibliometrics; Southeast asia; Political science; Regional science; Asian studies; Geography; History; Economics; China; Library science; Ancient history; Management; Computer science; Law; Philosophy; Aesthetics,,,,,,http://dx.doi.org/10.24198/jmpp.v8i2.54621,,10.24198/jmpp.v8i2.54621,,,0,,0,false,, -024-324-402-467-095,Artificial intelligence applications in the field of streamflow: a bibliometric analysis of recent trends,2024-06-06,2024,journal article,Hydrological Sciences Journal,02626667; 21503435,Informa UK Limited,United Kingdom,Gülhan Özdoğan Sarıkoç,"In this study, a bibliometric analysis technique is used for performance analysis and science mapping of streamflow research in artificial intelligence (AI) applications. This paper aims to examine the current trends in the literature using the Scopus database over the last 37 years. RStudio Bibliometrix software was used to analyze the study of titles, keywords, abstracts, and full texts for the 3000 publications to find out trends in AI models, publication types, journals, citations, authors, countries, and regions. In addition, the highest frequency AI-related keyword is Artificial Neural Networks which have been used in a total of 25587 times. The most common publication type, at 82.1%, is journal articles and the rate of country production is 25% for China. In recent years, streamflow research studies have significantly increased their use of AI applications.",69,9,1141,1157,Scopus; Streamflow; Field (mathematics); Computer science; Bibliometrics; Data science; Artificial intelligence; Library science; Geography; Political science; Cartography; Mathematics; MEDLINE; Drainage basin; Pure mathematics; Law,,,,"grants, or other support were received during the preparation",,http://dx.doi.org/10.1080/02626667.2024.2356006,,10.1080/02626667.2024.2356006,,,0,000-128-176-964-026; 000-564-983-746-501; 001-623-232-352-37X; 001-825-110-815-597; 002-052-422-936-00X; 002-864-016-633-058; 003-355-013-352-454; 003-375-341-175-328; 003-854-036-176-760; 008-256-272-861-446; 011-680-759-079-131; 012-027-927-043-707; 012-507-553-507-476; 013-507-404-965-47X; 013-890-317-889-469; 014-222-903-492-993; 014-425-628-772-199; 017-146-468-093-265; 019-517-232-882-914; 020-458-246-320-195; 021-017-001-524-555; 024-858-261-875-154; 027-188-139-928-821; 027-634-827-765-488; 028-389-462-353-754; 028-699-774-838-308; 032-312-947-370-965; 036-429-747-751-08X; 043-415-141-274-297; 043-818-787-252-210; 043-925-506-968-401; 045-270-546-608-783; 046-992-864-415-70X; 048-013-932-767-872; 050-148-236-017-306; 050-207-668-578-550; 053-094-537-530-97X; 058-171-906-054-250; 059-149-073-001-124; 059-598-901-852-594; 060-110-039-971-60X; 062-375-075-645-429; 063-789-423-782-849; 064-400-499-357-900; 064-420-766-656-39X; 067-626-596-126-240; 068-064-417-946-548; 069-269-035-556-929; 069-553-059-129-161; 078-196-453-282-360; 080-641-796-561-577; 081-828-308-116-498; 083-546-025-339-381; 083-952-612-246-933; 084-052-991-451-736; 089-771-039-531-226; 098-330-637-742-835; 100-683-498-354-739; 101-290-618-327-209; 104-655-240-494-934; 106-419-645-276-271; 108-842-686-334-205; 109-147-256-081-473; 112-066-474-948-69X; 115-345-147-918-224; 120-199-395-590-254; 120-215-318-300-863; 121-900-401-849-963; 122-615-899-662-066; 125-860-568-323-295; 126-257-629-889-939; 127-893-329-646-277; 131-054-303-123-803; 133-945-578-014-616; 134-714-756-047-364; 136-529-306-446-550; 136-734-038-680-801; 181-406-216-511-154; 192-135-671-580-685,1,false,, -024-887-273-815-207,Analysis of the literature on political marketing using a bibliometric approach,2019-10-29,2019,journal article,Journal of Public Affairs,14723891; 14791854,Wiley,United States,Krishna Teja Perannagari; Somnath Chakrabarti,"The current study presents a quantitative investigation of the literature on political marketing using a bibliometric approach. This study has analyzed 214 documents collected from the Web of Science database for the period between 1996 and 2018 using VOSviewer software and bibliometrix R package. Based on the insights gained from the analysis, the authors discuss the structural characteristics of various scientific agents involved in the publication process. The results of this study indicate that the literature on political marketing is highly fragmented and is still in its nascent stages. It further stresses the need to improve collaboration among researchers and promote this discipline within the research community.",20,1,,,Marketing; Political science; Politics,,,,,https://onlinelibrary.wiley.com/doi/10.1002/pa.2019,http://dx.doi.org/10.1002/pa.2019,,10.1002/pa.2019,2982688298,,0,002-349-133-624-621; 003-360-402-397-425; 011-190-203-334-262; 012-051-872-093-001; 013-375-400-569-574; 013-507-404-965-47X; 014-243-101-580-396; 015-685-046-463-65X; 020-037-658-420-621; 020-577-657-165-195; 023-927-221-065-800; 026-845-733-807-089; 029-420-167-353-195; 029-519-998-894-734; 030-692-448-438-720; 031-870-935-983-49X; 036-377-873-075-324; 047-956-381-301-108; 058-105-144-765-13X; 067-509-080-881-840; 069-226-188-348-16X; 072-131-863-693-642; 073-769-308-579-882; 087-351-664-539-721; 089-087-074-425-444; 096-837-787-652-755; 100-679-704-265-517; 101-752-490-869-458; 107-634-571-401-073; 110-309-885-074-596; 113-625-781-554-820; 122-415-544-444-960; 131-010-466-491-577; 138-160-974-979-585; 145-911-839-567-789; 152-069-942-718-17X; 188-107-477-968-27X,25,false,, -025-269-021-274-406,Analysis of environmental taxes publications: a bibliometric and systematic literature review,2021-01-06,2021,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Muhammad Farhan Bashir; Benjiang Ma; null Bilal; Bushra Komal; Muhammad Adnan Bashir,,28,16,20700,20716,Dividend; Regional science; Political science; Systematic review; Carbon tax; Degrowth; Environmental pollution; Pigou effect; Analytics; Developing country,Bibliometric analysis; Environmental tax; Frequency and cooccurrence analysis; Massive literature data; Research trends,Bibliometrics; China; Environmental Pollution; Publications; Taxes,,Ministry of Education of the People's Republic of China (2020MHL02005),https://link.springer.com/article/10.1007/s11356-020-12123-x https://pubmed.ncbi.nlm.nih.gov/33405155/,http://dx.doi.org/10.1007/s11356-020-12123-x,33405155,10.1007/s11356-020-12123-x,3119601444,,0,000-857-359-726-856; 000-986-465-360-772; 005-335-536-148-57X; 006-010-533-670-398; 006-493-145-319-968; 008-611-025-271-098; 009-161-630-654-32X; 013-507-404-965-47X; 015-249-067-927-117; 015-759-502-957-709; 015-962-102-926-595; 017-531-219-836-17X; 019-178-091-331-962; 019-902-888-738-457; 020-750-501-347-722; 021-207-674-049-565; 021-996-879-542-083; 022-165-169-567-218; 023-899-957-919-818; 033-208-682-822-618; 034-312-412-665-006; 035-511-529-925-21X; 035-882-510-679-787; 037-453-284-857-350; 037-620-931-513-163; 039-364-457-124-314; 041-145-303-622-646; 042-495-334-670-751; 042-853-073-408-604; 043-704-478-691-214; 044-249-916-992-258; 044-318-303-247-77X; 046-034-150-572-886; 046-192-329-405-635; 046-488-409-594-790; 048-047-552-255-213; 048-102-403-443-818; 048-202-542-155-419; 048-807-783-612-58X; 051-647-739-244-271; 054-344-263-957-321; 055-222-575-590-371; 057-923-746-378-266; 063-275-582-056-934; 063-739-170-981-528; 068-510-057-472-744; 072-111-061-501-858; 075-426-485-022-397; 078-154-202-403-556; 078-958-555-806-08X; 079-202-104-534-560; 080-098-700-699-490; 080-636-166-527-562; 088-913-032-181-504; 093-380-951-015-592; 095-360-757-922-425; 098-205-988-700-140; 098-288-118-872-279; 101-752-490-869-458; 106-115-137-253-548; 108-745-459-117-505; 128-877-861-475-482; 134-366-982-952-006; 135-847-822-812-710; 136-072-046-333-519; 139-312-136-165-685; 141-346-017-560-516; 141-479-002-820-02X; 150-257-198-624-188; 150-925-218-834-950; 155-424-766-371-818; 158-924-173-835-365; 163-204-659-450-102; 168-413-753-490-074; 169-276-705-430-649; 184-121-772-810-243,95,false,, -025-302-119-966-613,Bibliometric Analysis using Bibliometrix an R Package,2020-01-06,2020,journal article,Journal of Scientometric Research,23216654,Manuscript Technomedia LLP,,Hamid Derviş,,8,3,156,160,Political science; Information retrieval; R package; Bibliometric analysis,,,,,https://dblp.uni-trier.de/db/journals/jscires/jscires8.html#Dervis19 https://doi.org/10.5530/jscires.8.3.32 https://www.jscires.org/article/326,http://dx.doi.org/10.5530/jscires.8.3.32,,10.5530/jscires.8.3.32,2998021954,,0,,342,true,cc-by,hybrid -025-465-212-509-704,Industry 4.0 and its impact in plastics industry: A literature review,,2020,journal article,Journal of Industrial Information Integration,2452414x,Elsevier BV,Netherlands,Said Echchakoui; Noureddine Barka,,20,,100172,,Engineering; Industry 4.0; Bibliometric analysis; Industrial organization; Plastics industry; Internet of Things,,,,,https://www.sciencedirect.com/science/article/abs/pii/S2452414X20300479 https://doi.org/10.1016/j.jii.2020.100172,http://dx.doi.org/10.1016/j.jii.2020.100172,,10.1016/j.jii.2020.100172,3089255307,,0,002-052-422-936-00X; 002-904-296-739-781; 006-755-586-760-625; 013-507-404-965-47X; 013-541-969-076-695; 016-320-267-172-324; 016-655-706-124-813; 016-727-531-256-215; 017-750-600-412-958; 020-336-632-263-330; 021-152-254-601-282; 023-673-388-844-403; 025-633-214-579-319; 029-714-672-913-302; 031-118-626-580-878; 032-446-197-585-556; 034-768-039-318-254; 038-196-787-346-28X; 038-711-552-663-073; 038-904-037-813-023; 041-437-717-635-476; 045-422-273-148-899; 045-961-475-607-195; 047-150-751-577-417; 049-303-089-841-806; 050-158-324-603-670; 051-503-859-395-469; 051-862-424-436-262; 052-603-569-095-390; 056-613-736-885-432; 058-529-284-912-890; 062-948-572-785-006; 066-849-661-222-258; 068-970-970-192-264; 083-275-795-865-394; 086-265-049-859-785; 088-589-063-696-437; 088-862-853-155-242; 101-026-764-930-53X; 102-237-169-108-097; 102-868-472-436-983; 112-455-915-151-758; 119-210-960-502-851; 123-096-849-447-602; 123-365-319-409-994; 123-698-360-587-683; 125-184-556-716-218; 127-580-512-767-74X; 129-257-011-923-057; 130-109-783-341-840; 130-828-189-484-452; 138-561-175-358-392; 146-346-698-365-266; 195-638-802-395-994,36,false,, -025-905-594-877-460,Public sector marketing: a systematic literature review and research agenda,2024-12-10,2024,journal article,International Review on Public and Nonprofit Marketing,18651984; 18651992,Springer Science and Business Media LLC,Germany,Aline Regina Santos; Juliane Pierri Ardigo; Anderson Sasaki Vasques Pacheco,,,,,,Public Sector Marketing; Public sector; Public relations; Marketing; Marketing research; Marketing management; Sociology; Public service; Public value; Marketing science; Relationship marketing; Business; Political science; Law,,,,Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina,,http://dx.doi.org/10.1007/s12208-024-00424-7,,10.1007/s12208-024-00424-7,,,0,001-065-288-267-859; 002-546-548-660-475; 002-651-850-906-645; 003-651-636-745-20X; 005-292-370-759-68X; 005-443-470-189-456; 005-628-669-515-774; 007-403-097-074-963; 009-716-921-020-569; 011-172-075-313-141; 011-470-381-172-40X; 011-735-721-629-586; 011-818-953-495-840; 011-989-303-072-80X; 012-735-712-289-678; 013-426-793-937-573; 013-507-404-965-47X; 013-512-025-477-78X; 021-604-326-833-336; 023-656-936-450-911; 023-776-303-420-815; 024-194-170-324-171; 026-064-313-660-103; 027-022-616-316-052; 033-673-387-355-686; 037-537-846-795-330; 040-629-146-295-526; 043-438-001-705-851; 044-175-085-979-079; 048-105-295-333-93X; 048-504-808-324-827; 049-397-202-934-28X; 054-631-575-976-523; 055-484-086-408-663; 056-194-319-673-70X; 057-383-288-700-312; 061-080-555-341-243; 061-693-870-786-279; 063-224-617-571-013; 063-910-143-647-118; 065-720-306-504-310; 071-078-596-788-05X; 076-003-637-838-451; 077-162-449-720-696; 079-346-441-620-50X; 083-854-733-687-672; 083-918-004-443-029; 084-782-809-616-51X; 089-087-074-425-444; 092-864-033-895-513; 093-414-788-309-744; 094-465-155-757-56X; 096-945-469-668-135; 096-959-545-923-183; 097-510-213-279-375; 105-229-412-516-672; 108-746-688-230-32X; 110-361-933-236-405; 110-385-468-054-361; 130-436-027-268-877; 130-842-807-085-661; 133-011-634-446-570; 133-695-953-550-367; 136-357-040-801-966; 137-820-010-328-221; 138-220-696-403-202; 139-898-274-935-722; 153-854-225-234-13X; 163-199-941-805-09X; 175-173-673-003-110; 179-955-691-204-903; 180-874-270-563-159; 183-478-832-005-680; 188-098-216-502-867; 197-701-071-800-141,0,false,, -025-991-758-196-236,Advances of NOTCH2NLC Repeat Expansions and Associated Diseases: A Bibliometric and Meta-analysis.,2024-05-06,2024,journal article,Molecular neurobiology,15591182; 08937648,Springer Science and Business Media LLC,United States,Yangguang Lu; Yiqun Chen; Jiaqi Huang; Zihan Jiang; Yaoying Ge; Ruotong Yao; Jinxiu Zhang; Shangze Geng; Feng Chen; Qiaoqiao Jin; Guangyong Chen; Dehao Yang,,61,12,10227,10245,Meta-analysis; Publication bias; Funnel plot; Web of science; Demography; Subgroup analysis; Medicine; Bibliometrics; Population; MEDLINE; Scopus; Internal medicine; Biology; Library science; Environmental health; Biochemistry; Sociology; Computer science,"NOTCH2NLC - ; Bibliometrics; DNA repeat expansion; Meta-analysis; Neuronal intranuclear inclusion disease",Humans; Bibliometrics; Trinucleotide Repeat Expansion/genetics; Neurodegenerative Diseases/genetics; Nerve Tissue Proteins; Intercellular Signaling Peptides and Proteins,"NOTCH2NLC protein, human; Nerve Tissue Proteins; Intercellular Signaling Peptides and Proteins",National Natural Science Foundation of China (82302081); Fundamental Research Funds for the Central Universities (226-2023-0067); Natural Science Foundation of Zhejiang Province (LQ24H090003),,http://dx.doi.org/10.1007/s12035-024-04193-6,38709391,10.1007/s12035-024-04193-6,,,0,000-665-099-055-008; 007-332-344-953-24X; 007-915-362-877-206; 010-168-316-482-221; 010-286-503-077-990; 013-343-058-910-928; 013-507-404-965-47X; 014-009-836-235-811; 016-595-304-877-167; 017-946-746-721-993; 019-440-251-312-973; 019-636-552-835-414; 021-697-086-788-542; 024-947-636-979-545; 025-126-524-286-945; 026-236-832-261-882; 028-597-276-133-420; 031-711-524-606-464; 034-768-039-318-254; 035-929-062-677-790; 038-906-233-319-013; 044-475-085-535-018; 045-084-761-182-851; 045-416-413-742-937; 046-992-864-415-70X; 047-957-276-004-253; 048-259-754-221-34X; 050-076-466-587-646; 050-105-884-322-544; 051-905-317-081-07X; 054-569-058-444-567; 055-947-612-394-571; 073-255-355-830-445; 073-641-240-764-56X; 079-946-087-637-112; 080-729-512-647-720; 083-650-915-218-629; 084-122-421-227-303; 092-876-862-176-741; 093-727-739-157-075; 114-390-665-070-063; 115-418-816-723-382; 121-916-460-446-087; 122-165-303-308-061; 135-068-788-070-852; 141-917-200-182-847; 149-330-237-701-944; 151-066-640-236-837; 152-468-053-301-727; 171-041-145-350-880,0,false,, -026-161-845-899-195,Bibliometrix analisi: volontariato e community-based,,,,,,,,Valerio Brescia,"The terms voluntary and community-based have different interpretations and are often not considered together. There are no bibliometric analyzes aimed at investigating the meaning of the two terms, although this may be useful for defining future research strands and identifying new research strands not yet treated. Although numerous activities are considered in the third sector, it is not clear what the issues are most frequently addressed, and an understanding of the community-based term and the activities carried out in this form becomes even more difficult. The paper seeks to identify topics, keywords, countries, main searches by a number of citations and incidence and future lines of research. The sample analyzed considers a time range between 1974 and 2020.",1,1,1,22,Epistemology; Psychology; Meaning (existential); Time range; Community based; Sample (statistics); Incidence (geometry); Term (time),,,,,https://pkp.odvcasarcobaleno.it/index.php/ejvcbp/article/view/2 https://iris.unito.it/handle/2318/1741282 https://iris.unito.it/bitstream/2318/1741282/1/2-Article%20Text-97-1-10-20200608%20%281%29.pdf https://core.ac.uk/download/pdf/326909011.pdf,http://dx.doi.org/10.5281/zenodo.3870741,,10.5281/zenodo.3870741,3035940222,,0,,4,false,, -026-238-824-056-618,Research hotspots and trends in cancer rehabilitation: a bibliometric analysis (2013-2023).,2025-03-18,2025,journal article,Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer,14337339; 09414355,Springer Science and Business Media LLC,Germany,Ruijuan Cai; Hongsheng Lin; Qiyuan Mao; Chuchu Zhang; Ying Tan; Qianwen Cheng,"Advances in medical care have made cancer rehabilitation an essential component of comprehensive cancer treatment. However, bibliometric analyses in this field remain limited. This study maps the global research landscape of cancer rehabilitation over the past decade.; Relevant publications on cancer rehabilitation from 2013 to 2023 were retrieved from the Web of Science Core Collection (WoSCC) database. Bibliometric analysis was conducted using VOSviewer, CiteSpace, and the R package ""Bibliometrics.""; A total of 6743 publications from 98 countries demonstrated sustained growth, peaking in 2022. The USA (1581 publications) and China (974) led in research output, while the Netherlands recorded the highest citation impact (32.75 citations per paper). Key institutions included the University of Texas MD Anderson Cancer Center (148 publications) and Memorial Sloan Kettering Cancer Center (40.58 citations per paper). Supportive Care in Cancer ranked as the most influential journal. Research efforts primarily focused on exercise interventions (n = 404), quality of life (n = 688), and breast cancer rehabilitation (n = 440). Recent trends highlighted telemedicine, digital health, and breast cancer-related lymphedema.; This analysis highlights the dominance of high-income countries in cancer rehabilitation research and identifies exercise, quality of life, and breast cancer as enduring focal points. Emerging priorities include technology-driven interventions and lymphedema management. However, critical gaps remain, such as the underrepresentation of low-resource regions, limited focus on pediatric populations, and insufficient integration of advanced technologies (e.g., AI, wearables). Future efforts should emphasize equitable resource distribution, evidence-based pediatric rehabilitation models, and scalable technology-driven solutions to address global disparities and improve survivorship care.; © 2025. The Author(s).",33,4,296,,Nursing research; Medicine; Pain medicine; Rehabilitation; Bibliometrics; Environmental health; Gerontology; Nursing; Physical therapy; Library science; Pathology; Anesthesiology; Computer science,Bibliometrics; Cancer rehabilitation; Hotspots; Research activity; Trends,Humans; Bibliometrics; Neoplasms/rehabilitation; Quality of Life; Biomedical Research/trends; Telemedicine,,,https://link.springer.com/content/pdf/10.1007/s00520-025-09355-3.pdf https://doi.org/10.1007/s00520-025-09355-3,http://dx.doi.org/10.1007/s00520-025-09355-3,40100306,10.1007/s00520-025-09355-3,,PMC11919980,0,000-264-703-211-971; 001-608-848-366-539; 002-052-422-936-00X; 002-685-741-192-781; 003-601-811-587-160; 006-511-842-258-511; 006-607-127-339-44X; 009-912-036-168-112; 010-367-729-210-840; 011-886-302-695-747; 011-899-427-335-078; 016-187-938-341-812; 016-496-738-922-478; 017-203-494-322-058; 017-275-742-246-238; 017-300-737-144-757; 017-962-569-464-315; 021-078-810-987-030; 023-354-396-192-195; 024-086-157-376-702; 026-455-751-393-111; 031-644-127-610-235; 032-342-500-729-713; 034-693-977-144-189; 038-441-595-290-660; 042-925-682-253-636; 046-161-899-035-195; 046-667-028-966-574; 056-675-443-669-14X; 058-923-618-930-227; 064-097-462-205-592; 064-400-499-357-900; 067-138-108-080-069; 068-544-253-040-063; 069-511-868-544-95X; 076-355-164-749-289; 077-465-507-796-989; 078-844-256-606-71X; 080-977-108-232-315; 084-786-111-684-500; 084-904-184-655-385; 089-468-840-993-838; 090-476-872-676-699; 091-970-877-476-928; 092-062-550-269-321; 094-043-323-385-321; 095-147-738-038-594; 100-211-340-700-798; 103-004-177-236-098; 105-848-805-818-180; 109-484-086-811-257; 110-025-947-068-251; 131-557-307-603-85X; 136-499-308-169-505; 137-726-203-178-310; 140-576-984-769-54X; 151-046-729-067-912; 152-357-061-233-937; 153-527-209-467-103; 165-882-853-710-276; 167-373-519-239-682; 175-003-206-222-937; 184-812-291-987-577; 186-175-940-411-644; 196-262-709-815-054,0,true,cc-by-nc-nd,hybrid -026-486-567-500-791,Connecting smart mobility and car sharing using a systematic literature review. An outlook using Bibliometrix,,2024,journal article,Journal of Cleaner Production,09596526; 18791786,Elsevier BV,Netherlands,Elena-Mădălina Vătămănescu; Gandolfo Dominici; Victor-Emanuel Ciuciuc; Alexandra Vițelar; Flavia Gabriela Anghel,,485,,144333,144333,Systematic review; Car sharing; Sharing economy; Computer science; Engineering; Transport engineering; Political science; World Wide Web; MEDLINE; Law,,,,,,http://dx.doi.org/10.1016/j.jclepro.2024.144333,,10.1016/j.jclepro.2024.144333,,,0,000-410-859-068-967; 003-321-129-305-910; 004-580-153-309-367; 005-013-657-091-803; 005-400-907-900-918; 006-024-866-839-291; 006-057-509-386-053; 008-828-964-743-409; 008-992-007-744-121; 009-143-709-676-274; 009-361-606-253-565; 010-325-196-370-730; 010-561-115-802-461; 013-467-636-140-940; 013-507-404-965-47X; 013-524-854-219-241; 014-492-324-642-838; 015-849-799-455-011; 017-750-600-412-958; 018-005-992-606-191; 018-407-035-383-442; 018-897-093-119-070; 019-380-198-092-075; 020-385-342-650-974; 020-704-421-215-773; 021-724-033-742-197; 022-765-946-611-332; 022-881-510-208-356; 025-040-230-668-705; 025-182-988-531-802; 025-531-286-747-580; 028-019-158-572-532; 030-915-115-230-417; 032-517-326-134-723; 032-684-424-825-526; 032-897-858-917-259; 032-987-618-805-388; 033-189-007-441-896; 033-208-961-155-934; 034-169-626-907-374; 038-278-167-949-599; 040-020-850-094-461; 041-309-711-773-169; 041-435-421-851-357; 043-607-572-745-35X; 048-650-268-026-516; 048-655-004-699-007; 048-826-834-538-302; 052-307-980-114-68X; 052-329-456-889-822; 052-827-575-446-460; 053-878-592-441-545; 056-943-403-260-954; 057-280-700-665-386; 058-196-969-076-888; 060-570-851-935-121; 063-319-915-846-734; 064-372-871-540-352; 064-986-370-402-054; 068-042-673-469-173; 071-154-731-734-92X; 071-244-786-989-435; 071-298-750-557-984; 074-667-011-870-184; 077-151-351-469-700; 078-003-771-966-406; 078-253-138-633-480; 078-583-404-419-500; 079-131-834-947-265; 080-089-200-492-384; 080-113-482-532-344; 080-216-918-921-159; 080-435-906-332-883; 080-544-380-226-666; 083-519-595-535-970; 086-529-461-252-076; 090-477-703-312-32X; 090-505-542-169-993; 090-997-793-709-839; 091-334-881-479-50X; 092-925-577-654-378; 094-282-952-056-385; 095-454-432-305-709; 098-180-048-366-885; 099-405-810-903-613; 101-933-809-784-986; 103-856-858-034-07X; 105-048-112-385-479; 105-429-793-125-355; 107-415-189-958-583; 109-166-884-495-806; 109-792-205-844-006; 110-093-035-899-321; 113-187-943-724-857; 113-682-442-621-962; 114-153-144-726-638; 114-873-169-411-865; 115-425-544-791-941; 127-879-613-053-785; 130-000-474-582-959; 131-775-381-234-154; 134-489-587-853-454; 134-835-124-472-611; 138-331-610-583-006; 140-587-005-425-473; 141-026-656-461-626; 143-130-862-992-201; 143-212-150-315-535; 145-356-806-300-228; 149-064-082-678-815; 151-445-536-787-807; 154-397-754-854-794; 154-446-087-531-702; 164-221-405-163-331; 173-173-101-098-123; 174-064-616-111-618; 177-149-865-621-864; 184-794-884-042-564,4,true,cc-by,hybrid -026-552-777-300-600,Past and future of Industry 4.0: a bibliometric review using bibliometrix and VOSviewer,,2024,journal article,International Journal of Learning and Change,17402875; 17402883,Inderscience Publishers,Switzerland,Filipe Machado; Nelson Duarte; António Amaral; Madalena Araújo,"Industry 4.0 (I4.0) is a research field that accounted for an explosion of scientific publications since 2011. It is impractical to analyse the content of these many documents in a reasonable time (20,000). In these terms, the present research proposes a bibliometric review of this research field to identify its intellectual roots, research front, trends and gaps. The research settled for a must-read list, the past and current research themes and their evolution, and the supportive intellectual structure of the research field. It defined the research front under two general topics: 'I4.0 implementation' and 'I4.0 effects on sustainability', and it also presented thematic evolution trends and research gaps. Bibliometric analyses of the scientific field of I4.0 have several precedents: however, they have yet to embrace all the documents present in WOS and SCOPUS core collections. In this sense, the present article brings a novelty to the annals of the research field.",16,1,53,85,Scopus; Field (mathematics); Novelty; Bibliometrics; Data science; Computer science; Engineering ethics; Sociology; Political science; Library science; Engineering; MEDLINE; Psychology; Social psychology; Mathematics; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1504/ijlc.2024.135613,,10.1504/ijlc.2024.135613,,,0,,1,false,, -026-657-386-358-283,Superb microvascular imaging in tumour detection: global trends and research gaps,2024-08-01,2024,journal article,Chinese Journal of Academic Radiology,25208985; 25208993,Springer Science and Business Media LLC,,Ali Abougazia; Amin Sharifan,"To investigate the extent of utilising superb microvascular imaging in the detection of tumours in the literature. A comprehensive search was conducted in the Scopus database from inception until May 2024, focusing on tumours in specific organs and excluding certain study designs to ensure clinical relevance. No restrictions were placed on language or publication date. Bibliometric analysis was performed using Scopus, bibliometrix R package, and VOSviewer software to assess publication trends, citation analysis, country productivity, authorship, and keyword frequency. The search retrieved 144 documents published between 2015 and 2024, with a total of 2,072 citations and an average of 14.39 citations per document. The publication and citation trends showed that the number of publications has declined since 2021, along with a decrease in citations after 2018. China led in article production, followed by South Korea, Turkey, and Japan, with governmental sources playing a significant role in funding. Co-authorship analysis revealed limited international collaboration. Keyword analysis highlighted the prevalence of terms related to female, human, adult, sensitivity and specificity, and diagnostic imaging, with a focus on breast, thyroid, and liver cancers in superb microvascular imaging research. Research on the utilisation of superb microvascular imaging in tumour assessment within Western countries is imperative, given the current Asian-centric focus. International collaborations are crucial to assess the efficacy of superb microvascular imaging in tumour assessment. Additionally, a notable knowledge gap persists in tumour assessment beyond breast, thyroid, and liver cancers using superb microvascular imaging, warranting further investigation.",7,4,324,330,Scopus; Citation; China; Medicine; Productivity; Relevance (law); Medical physics; MEDLINE; Library science; Political science; Computer science; Law; Economics; Macroeconomics,,,,Danube University Krems University for Continuing Education,https://link.springer.com/content/pdf/10.1007/s42058-024-00163-y.pdf https://doi.org/10.1007/s42058-024-00163-y,http://dx.doi.org/10.1007/s42058-024-00163-y,,10.1007/s42058-024-00163-y,,,0,004-185-655-679-974; 010-896-795-344-250; 013-507-404-965-47X; 016-573-276-557-547; 025-641-210-919-478; 025-980-212-453-241; 028-728-563-956-910; 030-970-234-454-757; 031-460-334-238-150; 036-754-651-798-94X; 043-790-798-882-769; 047-811-451-545-582; 050-626-532-438-416; 062-539-192-681-136; 065-875-496-735-350; 082-787-880-894-547; 104-106-084-678-966; 128-389-157-895-640; 140-078-335-494-716; 195-217-682-619-838,2,true,cc-by,hybrid -026-670-023-327-476,Periodontal Disease and Alzheimer's: Insights from a Systematic Literature Network Analysis.,,2024,journal article,The journal of prevention of Alzheimer's disease,24260266; 22745807,Elsevier BV,Switzerland,A Villar; S Paladini; J Cossatis,"This study investigated the relationship between periodontal disease (PD) and Alzheimer's Disease (AD) through a Systematic Literature Network Analysis (SLNA), combining bibliometric analysis with a Systematic Literature Review (SLR). Analyzing 328 documents from 2000 to 2023, we utilized the Bibliometrix R-package for multiple bibliometric analysis. The SLR primarily centered on the 47 most globally cited papers, highlighting influential research. Our study reveals a positive correlation between Periodontal Disease (PD) and Alzheimer's Disease (AD), grounded in both biological plausibility and a comprehensive review of the literature, yet the exact causal relationship remains a subject of ongoing scientific investigation. We conducted a detailed analysis of the two main pathways by which PD could contribute to brain inflammation: (a) the Inflammatory Cascade, and (b) Microbial Involvement. The results of our SLNA emphasize the importance of oral health in reducing Alzheimer's risk, suggesting that managing periodontal health could be an integral part of Alzheimer's prevention and treatment strategies. The insights from this SLNA pave the way for future research and clinical practices, underscoring the necessity of interdisciplinary methods in both the investigation and treatment of neurodegenerative diseases like Alzheimer's. Furthermore, our study presents a prospective research roadmap to support ongoing advancement in this field.",11,4,1148,1165,Disease; Systematic review; Periodontal disease; Medicine; Alzheimer's disease; MEDLINE; Psychology; Pathology; Dentistry; Political science; Law,Alzheimer Disease; bibliometrics; neurodegenerative diseases; oral health; periodontal disease,Alzheimer Disease; Humans; Periodontal Diseases; Bibliometrics,,,https://eresearch.qmu.ac.uk/bitstream/20.500.12289/13725/1/13725.pdf https://eresearch.qmu.ac.uk/handle/20.500.12289/13725,http://dx.doi.org/10.14283/jpad.2024.79,39044527,10.14283/jpad.2024.79,,PMC11266257,0,001-057-194-818-402; 003-349-790-362-533; 004-035-408-319-169; 004-054-699-745-208; 005-169-965-296-625; 005-202-309-624-493; 005-373-567-447-043; 005-954-017-037-440; 006-114-739-384-828; 008-818-709-804-017; 008-931-099-267-238; 010-381-249-983-159; 011-428-721-136-378; 012-598-704-126-918; 012-920-060-299-452; 013-413-119-468-24X; 013-507-404-965-47X; 015-286-465-027-352; 016-868-925-057-330; 017-869-789-827-644; 018-255-094-832-375; 020-694-954-790-870; 021-403-889-773-292; 022-567-063-104-743; 023-673-868-514-198; 025-517-560-624-620; 027-408-222-411-489; 027-539-522-912-808; 033-858-901-306-467; 037-220-442-032-358; 037-287-961-533-900; 037-903-547-006-52X; 038-768-413-938-150; 042-415-506-281-320; 043-414-175-700-616; 051-048-920-685-229; 054-060-024-451-732; 058-986-825-757-816; 060-878-247-377-398; 061-680-766-695-657; 063-138-872-998-152; 064-166-341-243-388; 065-556-056-806-137; 065-926-056-691-080; 066-276-462-985-193; 069-908-254-272-326; 070-855-993-501-953; 072-330-709-831-252; 072-570-326-975-446; 073-187-128-382-812; 075-840-400-496-90X; 076-945-856-996-707; 079-327-194-218-105; 082-929-748-612-486; 086-408-916-373-122; 096-629-060-448-589; 099-299-458-610-646; 102-579-206-250-325; 103-441-267-768-827; 104-729-642-638-610; 105-277-169-824-179; 113-815-616-237-781; 128-286-270-789-880; 139-202-356-201-417; 184-266-153-730-583; 187-254-900-760-569,10,true,"CC BY, CC BY-NC, CC BY-NC-ND",gold -026-908-478-317-01X,Artificial intelligence in the service of entrepreneurial finance: knowledge structure and the foundational algorithmic paradigm,2025-02-06,2025,journal article,Financial Innovation,21994730,Springer Science and Business Media LLC,,Robert Kudelić; Tamara Šmaguc; Sherry Robinson,"Abstract; The study conducts a bibliometric review of artificial intelligence applications in two areas: the entrepreneurial finance literature, and the corporate finance literature with implications for entrepreneurship. A rigorous search and screening of the web of science core collection identified 1,890 journal articles for analysis. The bibliometrics provide a detailed view of the knowledge field, indicating underdeveloped research directions. An important contribution comes from insights through artificial intelligence methods in entrepreneurship. The results demonstrate a high representation of artificial neural networks, deep neural networks, and support vector machines across almost all identified topic niches. In contrast, applications of topic modeling, fuzzy neural networks, and growing hierarchical self-organizing maps are rare. Additionally, we take a broader view by addressing the problem of applying artificial intelligence in economic science. Specifically, we present the foundational paradigm and a bespoke demonstration of the Monte Carlo randomized algorithm.",11,1,,,Artificial neural network; Bespoke; Computer science; Artificial intelligence; Field (mathematics); Entrepreneurship; Bibliometrics; Data science; Service (business); Computational intelligence; Knowledge management; Management science; Sociology; Economics; Marketing; Data mining; Business; Finance; Mathematics; Advertising; Pure mathematics,,,,,http://arxiv.org/pdf/2311.13213 http://arxiv.org/abs/2311.13213,http://dx.doi.org/10.1186/s40854-025-00759-y,,10.1186/s40854-025-00759-y,,,0,000-237-617-371-473; 001-438-473-322-214; 002-729-869-280-926; 004-239-413-234-842; 005-211-158-981-593; 007-401-074-296-919; 008-251-678-155-290; 009-642-095-620-837; 011-512-552-426-180; 012-948-693-084-069; 013-507-404-965-47X; 014-998-725-345-883; 015-415-999-638-324; 016-052-331-799-087; 016-325-303-690-114; 016-790-514-063-798; 017-296-092-624-358; 017-703-103-885-453; 017-888-250-931-038; 019-091-640-020-971; 022-697-674-888-175; 025-090-428-893-09X; 025-766-536-992-842; 026-466-816-212-136; 029-917-356-828-296; 030-438-610-495-210; 031-402-331-384-958; 034-572-246-860-332; 034-885-668-549-795; 035-385-553-083-329; 036-210-818-321-241; 036-322-747-949-424; 041-252-693-988-726; 042-911-354-037-478; 043-699-518-243-544; 044-937-341-404-054; 045-118-156-568-396; 046-855-076-351-185; 046-992-864-415-70X; 047-528-778-315-857; 049-307-395-058-148; 049-677-483-711-977; 051-472-459-766-495; 053-042-926-137-472; 056-257-025-222-984; 060-478-043-555-698; 060-642-107-290-257; 060-833-748-323-575; 061-483-811-000-568; 062-051-558-006-17X; 062-329-287-193-586; 063-580-094-707-823; 066-408-626-481-533; 071-852-294-541-545; 072-491-495-986-757; 072-900-763-568-602; 074-506-519-971-659; 075-692-478-537-204; 078-115-305-452-674; 078-233-457-661-042; 081-787-145-749-515; 084-928-276-651-492; 089-751-234-475-049; 091-464-696-578-261; 092-267-855-670-836; 095-671-716-630-627; 096-914-481-676-793; 099-462-597-129-024; 101-752-490-869-458; 104-232-565-905-872; 112-471-034-541-019; 112-533-001-418-656; 112-612-799-391-776; 113-058-921-876-891; 127-768-678-581-747; 133-754-946-021-595; 134-289-564-817-649; 136-344-017-363-176; 147-894-074-856-183; 151-561-133-604-138; 152-490-973-524-764; 154-362-710-517-956; 159-857-041-312-502; 160-043-870-289-031; 162-217-666-453-818; 173-907-030-076-401; 181-681-484-417-689; 181-978-605-279-233; 187-836-173-435-347; 188-153-532-800-160; 190-002-372-538-442; 192-198-465-547-188,0,true,cc-by,gold -027-002-895-553-975,"Comprehensive analysis of research related to rehabilitation and COVID-19, hotspots, mapping, thematic evolution, trending topics, and future directions.",2023-10-13,2023,journal article,European journal of medical research,2047783x; 09492321,Springer Science and Business Media LLC,Germany,Siddig Ibrahim Abdelwahab; Manal Mohamed Elhassan Taha; Monira I Aldhahi,"This study conducted a comprehensive analysis of research pertaining to the intersection of rehabilitation and COVID-19 (COV-REH). The main aim of this study is to analyze the thematic progression and hotspots, detect emerging topics, and suggest possible future research directions in the COV-REH.; Appropriate keywords were selected based on the Medical Subject Headings (MeSH) PubMed database and the Scopus database were used to retrieve a total of 3746 original studies conducted in the English language. The data extraction was performed on June 30, 2023. VOSviewer and Bibliometrix utilize CVS and BibTex files to facilitate the performance analysis and generate visual maps. The performance indicators reported for the research components of the COV-REH were compiled using the Scopus Analytics tool.; From 2003 to 2023, 3470 authors from 160 organizations in 119 countries generated 3764 original research documents, with an annual growth of 53.73%. 1467 sources identified these scholarly works. Vitacca, M. (Italy), Harvard University (USA), and the USA published the most articles. This study included 54.1% of medical scholars. Telerehabilitation, exercise, quality of life, case reports, anxiety, and pulmonary rehabilitation were the primary themes of the COV-REH. One component of ""telerehabilitation"" is now the cardiac rehabilitation cluster. The trending topics in COV-REH are ""symptoms,"" ""protocol,"" and ""community-based rehabilitation"".; This study proposed several significant research directions based on the current thematic map and its evolution. Given that COV-REH investigations have been determined to be multidisciplinary, this study contributes conceptually to several fields and has wide-ranging implications for practitioners and policymakers.; © 2023. BioMed Central Ltd., part of Springer Nature.",28,1,434,,Scopus; Telerehabilitation; Rehabilitation; Thematic analysis; Protocol (science); Web of science; Multidisciplinary approach; Coronavirus disease 2019 (COVID-19); Medical education; Computer science; Psychology; MEDLINE; Data science; Health care; Medicine; Qualitative research; Telemedicine; Meta-analysis; Physical therapy; Alternative medicine; Political science; Sociology; Pathology; Social science; Disease; Infectious disease (medical specialty); Law,Bibliometrics; COVID-19; Knowledge structure; Mapping; Rehabilitation; Thematic evolution,Humans; Quality of Life; COVID-19; Anxiety; Exercise; Language,,,https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-023-01402-1 https://doi.org/10.1186/s40001-023-01402-1,http://dx.doi.org/10.1186/s40001-023-01402-1,37833811,10.1186/s40001-023-01402-1,,PMC10571379,0,000-667-231-896-402; 004-096-989-088-651; 004-139-949-808-586; 005-011-636-083-514; 005-497-832-918-606; 005-924-446-951-620; 008-761-839-293-396; 008-931-461-817-512; 009-227-458-183-19X; 012-541-062-798-079; 013-607-549-896-899; 013-892-806-490-474; 015-424-537-434-196; 016-460-728-542-821; 018-672-810-123-391; 018-893-501-990-992; 019-604-513-187-163; 022-356-424-187-530; 023-557-822-745-398; 025-127-462-093-017; 030-423-362-486-793; 031-133-976-710-121; 035-642-774-112-650; 037-673-698-741-715; 038-063-793-730-991; 038-625-231-441-444; 040-589-303-300-824; 042-142-595-540-396; 043-401-587-246-613; 044-329-782-568-012; 045-099-877-751-288; 045-837-268-050-963; 046-614-360-532-760; 049-659-857-493-54X; 049-992-878-928-871; 052-149-855-788-705; 053-794-452-514-302; 055-806-635-272-746; 057-537-713-941-440; 059-401-350-030-014; 062-501-808-210-460; 062-912-057-319-217; 063-023-631-123-208; 063-277-597-835-307; 064-090-919-935-324; 064-617-621-571-706; 066-771-370-332-054; 067-281-768-154-344; 067-534-691-496-532; 069-524-993-010-132; 071-878-836-294-733; 073-350-126-034-133; 074-932-967-705-807; 075-136-961-324-906; 079-438-437-924-920; 082-250-308-281-846; 082-828-051-054-67X; 085-789-243-721-211; 086-718-224-707-076; 089-352-531-484-437; 091-623-795-078-364; 097-847-178-426-547; 103-274-605-301-555; 118-667-102-705-664; 120-094-718-338-889; 121-451-991-375-778; 124-289-805-503-534; 130-762-749-589-625; 152-031-739-520-316; 153-948-486-602-911; 155-818-024-172-299; 160-950-985-516-862; 171-847-924-779-005; 191-517-248-288-123; 192-976-839-121-682,2,true,"CC BY, CC0",gold -027-017-212-915-431,Kubernetes as a Standard Container Orchestrator - A Bibliometric Analysis,2022-12-06,2022,journal article,Journal of Grid Computing,15707873; 15729184,Springer Science and Business Media LLC,Netherlands,Carmen Carrión,,20,4,,,Computer science; Orchestration; Cloud computing; Virtualization; Microservices; Scalability; Software deployment; Data science; Container (type theory); High availability; World Wide Web; Database; Software engineering; Distributed computing; Operating system; Engineering; Art; Musical; Mechanical engineering; Visual arts,,,,,,http://dx.doi.org/10.1007/s10723-022-09629-8,,10.1007/s10723-022-09629-8,,,0,002-052-422-936-00X; 004-525-121-117-238; 005-340-990-976-400; 009-981-620-276-98X; 010-998-626-881-909; 012-089-341-535-863; 012-167-313-925-582; 012-903-746-038-092; 013-507-404-965-47X; 014-129-634-820-525; 014-697-080-806-507; 017-341-774-084-627; 017-839-472-387-92X; 021-939-624-929-429; 028-509-332-165-02X; 029-783-454-831-869; 030-105-441-032-841; 030-808-118-865-852; 031-531-051-422-754; 032-294-255-945-063; 032-882-942-491-826; 033-065-512-756-501; 034-430-454-242-519; 035-822-623-350-481; 036-630-873-303-258; 037-805-870-613-865; 043-533-378-961-260; 045-285-086-434-816; 048-216-606-784-423; 050-171-084-115-139; 051-126-343-219-957; 051-661-562-220-549; 056-842-515-091-478; 058-998-027-851-38X; 063-575-167-672-080; 063-659-706-306-708; 064-400-499-357-900; 064-630-309-612-688; 069-824-833-857-961; 073-694-553-412-900; 076-672-340-157-266; 077-834-198-129-728; 077-922-671-109-643; 078-447-018-140-775; 085-129-488-142-062; 085-538-129-219-598; 085-804-733-272-247; 086-036-168-615-135; 092-542-706-662-967; 093-142-176-628-262; 097-573-686-048-284; 119-773-553-612-577; 120-586-553-592-272; 124-919-689-536-884; 127-175-817-840-929; 127-625-133-778-162; 127-763-348-376-721; 130-829-338-991-226; 139-092-373-220-80X; 155-666-155-478-749; 157-569-024-890-678; 160-814-917-851-355; 161-760-580-962-249; 179-726-149-691-386; 185-045-635-226-221; 185-332-080-184-196; 195-293-970-961-261; 199-640-705-271-621,15,false,, -027-164-174-474-291,Development in rural entrepreneurship and future scope of research: a bibliometric analysis,2024-08-13,2024,journal article,Journal of Global Entrepreneurship Research,22287566; 22517316,Springer Science and Business Media LLC,,Ruchita Pangriya; Shobha Pandey,,14,1,,,Scope (computer science); Entrepreneurship; Scopus; Thematic analysis; Multidisciplinary approach; Bibliometrics; Content analysis; Citation analysis; Variety (cybernetics); Qualitative research; Regional science; Sociology; Citation; Social science; Data science; Political science; Library science; Computer science; MEDLINE; Law; Programming language; Artificial intelligence,,,,,,http://dx.doi.org/10.1007/s40497-024-00397-1,,10.1007/s40497-024-00397-1,,,0,001-719-026-803-199; 002-796-750-754-24X; 002-797-713-550-146; 003-464-864-294-558; 004-563-719-577-930; 011-218-573-610-211; 013-524-854-219-241; 013-562-333-984-981; 016-267-613-628-823; 022-102-695-239-830; 029-420-167-353-195; 029-630-611-756-819; 038-083-768-141-739; 039-413-518-876-180; 040-660-541-109-143; 040-883-140-066-144; 042-198-588-100-870; 045-605-170-259-66X; 046-992-864-415-70X; 051-613-663-126-248; 051-647-739-244-271; 054-626-615-742-267; 055-273-552-334-543; 059-380-353-182-785; 061-444-603-217-939; 061-682-334-889-895; 063-238-281-808-810; 064-619-790-179-819; 076-999-281-997-349; 081-214-824-917-420; 081-691-901-343-152; 085-207-092-965-362; 089-241-293-864-917; 100-828-997-004-340; 104-375-104-807-207; 116-044-451-563-162; 128-221-150-778-477; 129-101-144-182-888; 134-257-567-454-971; 142-366-907-228-19X; 149-086-327-305-10X; 157-908-239-881-932; 166-631-472-968-687; 173-601-618-703-611; 176-211-945-520-033; 184-149-844-861-248,0,false,, -027-495-891-012-803,The Journal Buildings: A Bibliometric Analysis (2011–2021),2022-01-02,2022,journal article,Buildings,20755309,MDPI AG,,Zhiwen Xiao; Yong Qin; Zeshui Xu; Jurgita Antucheviciene; Edmundas Kazimieras Zavadskas,"The journal Buildings was launched in 2011 and is dedicated to promoting advancements in building science, building engineering and architecture. Motivated by its 10th anniversary in 2021, this study aims to develop a bibliometric analysis of the publications of the journal between April 2011 and October 2021. This work analyzes bibliometric performance indicators, such as publication and citation structures, the most cited articles and the leading authors, institutions and countries/regions. Science mappings based on indicators such as the most commonly used keywords, citation and co-citation, and collaboration are also developed for further analysis. In doing so, the work uses the Scopus database to collect data and Bibliometrix to conduct the research. The results show the strong growth of Buildings over time and that researchers from all over the world are attracted by the journal.",12,1,37,37,Scopus; Citation; Work (physics); Library science; Citation analysis; Web of science; Bibliometrics; Citation impact; Computer science; Data science; Operations research; Political science; Engineering; MEDLINE; Mechanical engineering; Law,,,,National Natural Science Foundation of China; National Natural Science Foundation of China,https://www.mdpi.com/2075-5309/12/1/37/pdf?version=1641371383 https://doi.org/10.3390/buildings12010037,http://dx.doi.org/10.3390/buildings12010037,,10.3390/buildings12010037,,,0,004-206-718-074-930; 008-281-751-240-211; 013-507-404-965-47X; 017-854-681-337-350; 021-136-500-898-924; 021-306-702-324-119; 021-916-362-778-920; 023-224-333-418-040; 023-620-543-445-199; 023-927-221-065-800; 031-531-051-422-754; 034-819-603-378-053; 043-228-201-072-424; 046-550-889-589-425; 047-470-769-444-762; 054-818-565-070-154; 057-803-697-074-453; 061-110-528-065-700; 065-759-371-637-871; 066-211-704-101-585; 070-572-514-784-002; 071-958-550-139-56X; 072-144-990-567-166; 073-775-823-470-313; 074-279-238-515-510; 079-905-177-988-580; 091-722-903-088-88X; 111-441-932-372-655; 116-200-993-474-887; 123-202-581-406-928; 123-321-230-739-538; 125-531-613-225-655; 134-987-378-875-755; 138-434-162-063-622; 148-292-319-388-823; 173-171-622-385-276; 174-804-796-975-19X; 177-882-177-384-49X; 185-421-860-898-573,24,true,cc-by,gold -027-545-228-876-499,Harnessing digital technologies for triple bottom line sustainability in the banking industry: a bibliometric review,2024-06-12,2024,journal article,Future Business Journal,23147202; 23147210,Springer Science and Business Media LLC,,Megha Garg; Parveen Kumar,"Abstract; The interconnection between the consequences of digital technologies and their impact on triple bottom line sustainability in the banking industry has emerged as a dynamic, multidisciplinary, and eclectic research area of global significance. Nevertheless, applying a systematic literature network analysis in this field has not yet been attempted. Therefore, this paper aims to investigate academic research by integrating different knowledge systems. To conduct this comprehensive analysis, this study employed the contextualized systematic literature review and bibliometric approaches method to make inferences from 154 publications obtained from the Scopus and Web of Science databases for the years 2012–2024 by using the biblioshiny tool. The study’s findings exhibited a noticeable upsurge in research trends in the last five years. With 64 publications, 2023 was the most productive year, and 2018 had the most influence with 188 citations. China, Italy, Spain, Egypt, and Malaysia were the most productive countries regarding citation performance. This study highlights the counterintuitive connection between digitalization, financial inclusion, sustainability, fintech, and sustainable development by providing support with recent literature to reflect the current developments in the field. The themes encountered here are crucial for regulators and practitioners who aim to capitalize on the mutually reinforcing nature of the two phenomena in the banking industry.",10,1,,,Scopus; Sustainability; Triple bottom line; Multidisciplinary approach; Bibliometrics; Citation; Counterintuitive; Inclusion (mineral); Field (mathematics); Scientific literature; Business; Marketing; Knowledge management; Political science; Computer science; Sociology; Library science; Social science; Ecology; Mathematics; Biology; Philosophy; Paleontology; MEDLINE; Epistemology; Pure mathematics; Law,,,,,https://fbj.springeropen.com/counter/pdf/10.1186/s43093-024-00336-2 https://doi.org/10.1186/s43093-024-00336-2,http://dx.doi.org/10.1186/s43093-024-00336-2,,10.1186/s43093-024-00336-2,,,0,000-213-670-798-752; 000-703-311-870-70X; 002-249-297-865-984; 002-884-870-098-654; 004-067-039-768-976; 005-434-636-280-811; 005-633-774-377-55X; 006-760-028-467-156; 006-810-383-977-452; 007-233-126-244-628; 007-581-025-024-301; 008-118-491-582-812; 009-204-255-635-342; 009-698-177-416-269; 010-191-791-723-448; 012-461-150-359-252; 013-507-404-965-47X; 014-043-555-699-168; 015-550-845-293-820; 016-254-941-358-743; 018-689-206-364-026; 020-248-336-627-769; 021-558-443-408-051; 022-086-898-155-306; 023-798-087-793-592; 023-927-221-065-800; 025-302-119-966-613; 029-545-121-880-538; 032-410-737-952-720; 033-997-136-772-646; 034-105-921-015-739; 035-177-703-125-971; 035-953-579-141-278; 036-131-266-964-023; 041-228-380-588-692; 042-228-490-689-212; 043-959-528-482-694; 045-585-109-778-81X; 045-926-029-380-855; 046-423-755-859-416; 046-992-864-415-70X; 047-580-627-635-421; 049-332-097-431-041; 050-275-061-652-579; 051-281-303-936-409; 051-720-046-820-65X; 052-001-208-343-944; 052-603-569-095-390; 053-344-090-375-529; 053-444-103-367-033; 054-842-941-091-224; 056-574-183-279-838; 057-429-099-959-158; 058-397-403-689-299; 058-680-151-296-053; 064-569-148-927-282; 067-155-502-132-503; 069-597-922-997-328; 075-359-490-475-342; 077-946-279-594-919; 078-728-779-452-651; 081-501-493-147-936; 081-826-955-273-079; 083-875-912-342-840; 084-626-510-015-870; 085-625-594-010-891; 087-096-450-209-297; 089-046-210-694-577; 089-448-407-850-125; 094-023-744-239-340; 096-778-794-348-340; 097-653-190-979-595; 097-759-335-124-834; 099-828-678-969-096; 102-554-620-566-922; 104-945-575-435-739; 105-325-288-319-152; 106-799-073-307-761; 107-573-611-075-561; 108-317-963-192-028; 117-541-634-421-603; 119-917-135-213-952; 121-155-069-523-672; 121-813-144-996-86X; 123-202-581-406-928; 128-845-664-928-167; 130-971-146-033-311; 133-165-318-273-139; 137-398-227-200-80X; 137-838-710-692-863; 140-032-117-886-523; 140-184-936-056-163; 143-936-693-364-687; 145-732-715-356-097; 145-877-484-444-416; 146-340-710-814-806; 147-244-664-952-189; 150-467-309-378-385; 150-947-726-142-00X; 154-450-738-247-88X; 155-406-765-045-392; 158-057-680-669-741; 168-817-200-657-672; 170-702-031-706-868; 171-651-155-189-240; 177-066-423-855-010; 193-876-808-596-982; 195-094-129-336-528; 196-893-352-371-948; 198-085-358-708-270; 198-861-124-041-804; 199-780-649-881-621,4,true,cc-by,gold -028-874-048-514-697,Review on Shariah Supervisory Board Studies using Bibliometrix,2024-01-04,2024,journal article,Maqasid al-Shariah Review,30262283,Sharia Economic Applied Research and Training (SMART) Insight,,Amelia Tri Puspita; Mohammad Mahbubi Ali,"The rapid development of the Indonesian economy is influenced by the emergence of both sharia and non-sharia financial institutions. In Islamic banking, so that all parties' interests can be met properly, the management and supervision structure will involve four parties, namely: shareholders (board of commissioners), bank management, Sharia Supervisory Board (DPS) and/or National Sharia Council (DSN), and depositors. In an effort to purify the services of Islamic financial institutions to be truly in line with the provisions of Islamic sharia, the existence of a Sharia Supervisory Board (DPS) is absolutely necessary. DPS is a key institution that ensures that the operational activities of Islamic financial institutions are in accordance with sharia principles. This study aims to determine the development map and trend of Shariah Supervisory Board published by reputable journals in the field of Economics and Islamic finance. The data analyzed were more than 114 publications of research publications indexed by Scopus. The export data was then processed and analyzed using the R Biblioshiny application program to determine the bibliometric map of the development of the Shariah Supervisory Board.",2,2,,,Sharia; Supervisory board; Accounting; Islam; Business; Indonesian; Shareholder; Financial institution; Finance; Corporate governance; Philosophy; Linguistics; Theology,,,,,https://journals.smartinsight.id/index.php/MSR/article/download/345/322 https://doi.org/10.58968/msr.v2i2.345,http://dx.doi.org/10.58968/msr.v2i2.345,,10.58968/msr.v2i2.345,,,0,,0,true,cc-by-nc,hybrid -029-363-666-909-989,Key developments and hotspots in programmed cell death in liver cancer pain: a bibliometric study.,2025-06-01,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Yanmei Yang; Yongjin He; Ping Zhang; Chunyan Wang,"This bibliometric study aimed to elucidate key developments, influential publications, and emerging research hotspots on programmed cell death (PCD) in liver cancer-associated pain, thereby providing guidance for future mechanism-based, patient-centered therapies.; A comprehensive search was performed in the Web of Science using terms encompassing liver cancer, pain, and various PCD modalities. After multi-stage screening for relevance and quality, a dataset of 324 articles (2000-2024) was analyzed. Tools such as VOSviewer and Bibliometrix facilitated performance analysis, co-citation mapping, keyword clustering, and trend topic identification.; The annual publication output increased notably after 2015, reflecting intensified interest in molecular pathways (apoptosis, ferroptosis, autophagy) and their clinical implications. China led in publication volume, while the USA and several European countries demonstrated high impact and extensive international collaborations. Keyword analysis revealed five thematic clusters, highlighting the prominence of inflammation, NF-κB signaling, oxidative stress-mediated apoptosis, combined therapeutic approaches, and metastasis-driven pain. Highly cited articles focused on flavonoids in apoptosis, immunogenic cell death, and cyclooxygenase-2 regulation, underscoring a shift toward integrative regimens that target both tumor progression and pain mechanisms.; Programmed cell death research in liver cancer pain has evolved into a rapidly expanding, multidisciplinary field. Findings point to a paradigm shift from purely cytotoxic strategies to more holistic approaches that merge immunotherapy, biomarker-driven diagnosis, and targeted interventions aimed at alleviating pain while controlling tumor growth. These insights lay the groundwork for precision-oriented, mechanism-based treatments that address the multifaceted challenges faced by patients with advanced liver cancer.; © 2025. The Author(s).",16,1,979,,,Apoptosis; Autophagy; Immunotherapy; Liver cancer pain; Programmed cell death,,,,,http://dx.doi.org/10.1007/s12672-025-02759-x,40450638,10.1007/s12672-025-02759-x,,PMC12127255,0,001-158-010-329-026; 001-814-238-956-993; 003-917-717-551-920; 005-652-813-182-215; 007-871-386-578-954; 012-360-955-938-654; 013-674-341-191-11X; 013-745-328-117-842; 014-590-747-886-139; 015-118-009-533-11X; 017-549-477-499-028; 022-193-689-181-827; 030-612-337-252-816; 030-868-610-579-983; 032-800-087-402-797; 033-688-534-443-849; 034-504-891-323-105; 036-871-634-296-06X; 039-664-273-290-304; 039-984-369-673-169; 043-331-267-241-185; 048-247-040-180-365; 049-639-468-729-741; 050-732-306-288-447; 052-559-850-345-034; 061-064-383-056-824; 061-690-639-772-022; 062-348-214-020-354; 062-757-709-950-50X; 063-209-427-581-32X; 065-320-020-823-655; 066-906-728-907-189; 080-404-241-895-435; 082-067-175-962-449; 083-295-029-917-894; 084-570-790-507-414; 085-516-233-379-965; 091-887-038-661-789; 091-906-161-515-825; 098-183-920-612-991; 102-011-183-592-311; 103-615-487-908-42X; 103-716-831-455-574; 105-540-443-374-787; 110-156-701-657-275; 113-917-697-265-553; 116-291-875-581-610; 122-518-053-082-418; 123-509-350-870-359; 127-347-758-667-406; 133-473-647-054-580; 137-521-228-229-381; 139-405-480-379-79X; 145-702-800-058-337; 147-766-950-317-90X; 151-793-220-553-933; 153-334-314-441-967; 154-958-351-540-122; 158-491-690-230-62X; 167-577-548-935-075; 168-777-642-934-004; 186-959-374-269-377,0,true,cc-by,gold -029-612-438-336-079,A Meta-Analysis of the Relationship Between Organizational Citizenship Behavior and Employee Performance,2024-04-15,2024,journal article,Asian Journal of Management Analytics,29634547,PT Formosa Cendekia Global,,Pratiwi Widyastuti; Sri Handari Wahyuningsih,"This paper aims to identify research trends on values and organizational citizenship behavior (OCB) and their effect on employee performance globally. The Method used in this study is qualitative research with literature review. As for the data found, 109 documents were obtained and analyzed 2014-2023. This dataset was converted to CSV format andfor Bibliometrix in the analysis using VOSviwer. The study included publication distribution year, country, keywords, and authors. This study's findings show that the research trend from 2014 to 2023 indexed by Scopus has increased. 2020 became the year with the highest number of research publications on Citizenship Organizational Behavior and Employee Performance. Indonesia was identified as the country that contributed the most to the publication of this research, with studies in Citizenship Organizational Behavior, Job Rotation, and Physical Work Environment. This paper reveals the research trends and areas of Citizenship, Organizational Behavior, and employee performance. The results help scholars quickly understand the research of Citizenship Organizational Behavior",3,2,299,310,Organizational citizenship behavior; Citizenship; Psychology; Organizational behavior; Employee research; Social psychology; Organizational commitment; Business; Political science; Law; Politics,,,,,https://journal.formosapublisher.org/index.php/ajma/article/download/8492/8651 https://doi.org/10.55927/ajma.v3i2.8492,http://dx.doi.org/10.55927/ajma.v3i2.8492,,10.55927/ajma.v3i2.8492,,,0,,0,true,cc-by,hybrid -029-625-701-807-177,Forecasting of the COVID-19 Epidemic: A Scientometric Analysis,2021-03-29,2021,,,,,,Ferdias Pandri; Saleh Ahmar Ansari,"This study presented a scientometric analysis of scientific publications with discussions of ; forecasting and COVID-19. The data of this study were obtained from the Scopus database using ; the keywords: ( TITLE-ABS-KEY (forecast) AND TITLE-ABS-KEY (covid)) and the data ; were taken on March 26, 2021. This study was a scientometric study. The data were subsequently ; analyzed using the VosViewer and Bibliometrix R Package. The results showed that “COVID�19” was the keyword most frequently used by researchers, followed by “forecasting” and ; “human”. Authors who discussed the topic of forecasting COVID-19 come from 83 different ; countries/regions, with the most articles sent by authors from the USA.; Keywords: COVID-19; forecasting; scientometric.",,,,,Geography; Information retrieval; R package; Coronavirus disease 2019 (COVID-19); Scopus,,,,,http://repository.lppm.unila.ac.id/30563/ https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=10030&context=libphilprac https://digitalcommons.unl.edu/libphilprac/5415/,http://repository.lppm.unila.ac.id/30563/,,,3163023927,,0,002-052-422-936-00X; 003-992-355-629-718; 004-259-882-296-737; 008-305-597-627-808; 009-118-598-270-671; 013-507-404-965-47X; 017-524-162-077-233; 019-344-585-198-226; 020-597-922-918-046; 022-197-319-262-812; 025-187-568-997-422; 025-190-814-977-994; 026-417-789-445-557; 026-769-386-366-589; 028-779-189-428-615; 033-461-550-376-264; 034-088-484-147-896; 042-834-888-791-284; 054-227-953-368-783; 055-372-825-615-564; 059-585-719-270-712; 064-598-735-036-559; 065-545-309-411-827; 074-642-513-946-424; 084-731-213-533-414; 086-931-819-551-851; 095-790-409-092-47X; 099-655-812-877-633; 107-489-026-593-999; 107-888-254-504-036; 113-389-037-530-490; 147-974-967-825-624; 155-092-242-477-277,0,false,, -029-637-026-652-308,Exploring Trends in New Media Literacy (NML) Field: A Bibliometric Analysis Using Bibliometrix R‑Tool,2025-03-03,2025,journal article,Galactica Media: Journal of Media Studies,26587734,Limited Liability Company Scientific Industrial Enterprise - Genesis. Frontier. Science,,Burak Ili,"; In the context of rapidly evolving digital technologies, the dissemination of information in new media is accompanied by a number of challenges, including the proliferation of disinformation, fake news, and information pollution. Notwithstanding the growing importance of new media literacy (NML), its integration into educational programs and public policies remains insufficient. Moreover, research often focuses on narrow aspects or specific audiences, which limits the understanding of NML’s societal impact. The objective of this study is to conduct a bibliometric analysis of extant research on new media literacy with a view to identifying key trends, research gaps and priority directions. A review of 217 publications from the Scopus database revealed that the primary research topics include the use of new media, social media, combating fake news, and fostering participatory culture. A geographic analysis identified the United States, Türkiye, and China as the countries with the most research output in this field. The study highlights the need for more in-depth educational programs, greater awareness among diverse social groups, and the use of interactive technologies to develop critical thinking skills. The findings are intended for researchers in media literacy, educators, policymakers, and program developers interested in advancing NML and integrating it into societal and educational practices.; ",7,1,207,231,Field (mathematics); Literacy; Computer science; Data science; Sociology; Mathematics; Pedagogy; Pure mathematics,,,,,,http://dx.doi.org/10.46539/gmd.v7i1.535,,10.46539/gmd.v7i1.535,,,0,,0,true,cc-by,gold -030-173-947-430-569,Participatory budgeting and climate change: a bibliometric analysis,2022-03-22,2022,preprint,,,Springer Science and Business Media LLC,,Gleidcy Helle dos Helle dos Reis Rocha; Claúdia Costa,"Abstract;

Climate change is an undeniable and tangible reality with consequences that have gradually become more serious, for this reason, is necessary to find tools to prevent further damage from occurring. In this context that the Participatory Budget fits, which over the last few years, has been commonly used as a tool for mitigating and adapting to climate change. Thereupon, the scope of this study is to carry out a mapping of academic production related to participatory budgeting and climate change. For this purpose, we chose to use bibliometric techniques, using two software: Bliblioshiny by Bibliometrix and Vosviewer, making it possible to analyze citations, co-citations and text of articles obtained from Scopus and Web of Science databases. As for the results, it was possible to observe that despite the imminent need to study the themes, there is a tiny amount of works, indicating that there is still much to be done.

",,,,,Scopus; Scope (computer science); Climate change; Citizen journalism; Context (archaeology); Web of science; Political science; Data science; Computer science; Geography; World Wide Web; MEDLINE; Ecology; Archaeology; Law; Biology; Programming language,,,,,https://www.researchsquare.com/article/rs-1451397/latest.pdf https://doi.org/10.21203/rs.3.rs-1451397/v1,http://dx.doi.org/10.21203/rs.3.rs-1451397/v1,,10.21203/rs.3.rs-1451397/v1,,,0,,0,true,cc-by,green -031-051-447-378-152,"SCHOLARLY PUBLICATIONS OF THE MAHARAJA SAIYAJIRAO UNIVERSITY OF BARODA, VADODARA : A BIBLIOMETRICS STUDY",2018-07-30,2018,journal article,Towards Excellence,0974035x,Gujarat University,,Priyanki Vyas; Roma Asnani Mrs.,"Many evaluation studies have been carried out with the help of bibliometrics study to know the growth ofresearch papers at national and international level, scientific productivity of authors and institutions, most relevant journals and their impact factor, citation analysis etc. This paper aimed to analysis of 2200 publications of with 23268 citations Maharaja Saiyajirao University of Baroda by using three indices, which hosted on Web of Knowledge platform i.e. Science Citation Index, Social Science Citation Index and Arts and Humanities; Citation Index along with citations during the period of 2009 to 2018. Bibliometrix R tool used for summarizing results of Web of Science Data and VOSviewer used to demonstrate country’s collaborationmapping analysis.",,,202,208,Sociology; Library science; Bibliometrics,,,,,http://dx.doi.org/10.37867/100225,http://dx.doi.org/10.37867/100225,,10.37867/100225,3038365964,,0,009-086-047-657-438; 015-285-318-650-756; 154-210-324-244-74X,0,true,,bronze -031-301-234-883-461,"Data mining and analysis of scientific research data records on Covid 19 mortality, immunity, and vaccine development in the first wave of the Covid 19 pandemic",2020-07-04,2020,journal article,Diabetes & metabolic syndrome,18780334; 18714021,Elsevier BV,Netherlands,Petar Radanliev; David De Roure; Robert Walton,"In this study, we investigate the scientific research response from the early stages of the pandemic, and we review key findings on how the early warning systems developed in previous epidemics responded to contain the virus. The data records are analysed with commutable statistical methods, including R Studio, Bibliometrix package, and the Web of Science data mining tool. We identified few different clusters, containing references to exercise, inflammation, smoking, obesity and many additional factors. From the analysis on Covid-19 and vaccine, we discovered that although the USA is leading in volume of scientific research on Covid 19 vaccine, the leading 3 research institutions (Fudan, Melbourne, Oxford) are not based in the USA. Hence, it is difficult to predict which country would be first to produce a Covid 19 vaccine.",14,5,1121,1132,Data mining; Geography; Warning system; Data records; Coronavirus disease 2019 (COVID-19); Pandemic; China; Immunity; Data sharing; Scientific literature; News media; Medicine; Multiple correspondence analysis,Computable statistical analysis; Covid-19; Data mining; Immunity; Mortality; Vaccine,"Betacoronavirus/isolation & purification; Biomedical Research; COVID-19; COVID-19 Vaccines; Coronavirus Infections/immunology; Data Mining/methods; Humans; Pandemics/prevention & control; Pneumonia, Viral/immunology; SARS-CoV-2; Viral Vaccines/therapeutic use",COVID-19 Vaccines; Viral Vaccines,"The Engineering and Physical Sciences Research Council; Cisco Systems, USA",http://arxiv.org/pdf/2009.05793.pdf https://arxiv.org/abs/2009.05793 https://ui.adsabs.harvard.edu/abs/2020arXiv200905793R/abstract http://arxiv.org/abs/2009.05793,http://dx.doi.org/10.1016/j.dsx.2020.06.063,32659695,10.1016/j.dsx.2020.06.063,3040683741; 3104716578,PMC7335244,0,004-470-552-654-769; 010-614-838-735-932; 013-507-404-965-47X; 023-906-048-099-886; 031-706-925-253-069; 035-433-365-909-422; 040-723-926-404-616; 043-010-370-281-604; 044-644-693-164-059; 065-213-757-089-527; 070-547-468-610-233; 072-006-703-548-726; 080-386-658-039-347; 085-448-838-401-764,50,true,implied-oa,green -031-496-840-866-744,A risk-based soft sensor for failure rate monitoring in water distribution network via adaptive neuro-fuzzy interference systems.,2023-07-27,2023,journal article,Scientific reports,20452322,Springer Science and Business Media LLC,United Kingdom,Mohammad Gheibi; Reza Moezzi; Hadi Taghavian; Stanisław Wacławek; Nima Emrani; Mohsen Mohtasham; Masoud Khaleghiabbasabadi; Jan Koci; Cheryl S Y Yeap; Jindrich Cyrus,"Water Distribution Networks (WDNs) are considered one of the most important water infrastructures, and their study is of great importance. In the meantime, it seems necessary to investigate the factors involved in the failure of the urban water distribution network to optimally manage water resources and the environment. This study investigated the impact of influential factors on the failure rate of the water distribution network in Birjand, Iran. The outcomes can be considered a case study, with the possibility of extending to any similar city worldwide. The soft sensor based on the Adaptive Neuro-Fuzzy Inference System (ANFIS) was implemented to predict the failure rate based on effective features. Finally, the WDN was assessed using the Failure Modes and Effects Analysis (FMEA) technique. The results showed that pipe diameter, pipe material, and water pressure are the most influential factors. Besides, polyethylene pipes have failure rates four times higher than asbestos-cement pipes. Moreover, the failure rate is directly proportional to water pressure but inversely related to the pipe diameter. Finally, the FMEA analysis based on the knowledge management technique demonstrated that pressure management in WDNs is the main policy for risk reduction of leakage and failure.",13,1,12200,,Failure rate; Failure mode and effects analysis; Computer science; Reliability engineering; Adaptive neuro fuzzy inference system; Fuzzy logic; Water leakage; Artificial neural network; Leakage (economics); Fuzzy inference system; Environmental science; Engineering; Fuzzy control system; Materials science; Artificial intelligence; Composite material; Economics; Macroeconomics,,,,,https://www.nature.com/articles/s41598-023-38620-w.pdf https://doi.org/10.1038/s41598-023-38620-w,http://dx.doi.org/10.1038/s41598-023-38620-w,37500665,10.1038/s41598-023-38620-w,,PMC10374646,0,003-512-908-463-733; 008-956-473-846-928; 009-259-851-943-761; 009-519-792-503-093; 011-152-569-916-77X; 011-225-586-840-281; 011-745-381-406-683; 015-023-385-428-59X; 015-708-298-388-069; 018-031-849-737-833; 019-015-730-368-563; 020-578-981-935-408; 020-920-966-652-363; 021-587-130-612-88X; 024-175-788-387-680; 026-426-795-969-909; 027-286-456-034-265; 028-247-244-108-271; 028-861-844-207-871; 029-863-809-376-042; 033-358-551-343-821; 035-429-936-749-521; 037-784-179-938-358; 043-842-456-390-387; 044-657-403-446-094; 050-162-900-696-812; 053-289-925-699-62X; 054-850-360-516-378; 057-767-564-471-417; 069-158-374-992-459; 069-337-378-272-09X; 069-646-756-831-573; 081-336-344-319-574; 083-525-434-021-953; 087-082-466-063-221; 091-341-992-034-613; 093-281-560-216-967; 098-650-685-926-842; 106-031-424-643-348; 109-184-810-682-86X; 111-431-938-592-182; 117-326-237-453-167; 118-744-506-139-730; 121-649-021-480-765; 125-978-461-488-886; 129-316-076-200-420; 130-295-585-370-458; 136-309-587-585-682; 140-696-018-367-033; 141-309-106-201-600; 143-862-624-804-598; 150-092-317-287-039; 153-008-677-786-303; 155-017-909-428-255; 155-760-850-300-919; 168-575-305-249-692; 172-659-740-012-801; 191-208-424-161-369; 196-091-638-566-295,7,true,"CC BY, CC BY-NC-ND",gold -032-087-994-696-724,Knowledge mapping of programmed cell death in osteonecrosis of femoral head: a bibliometric analysis (2000-2022).,2023-11-14,2023,journal article,Journal of orthopaedic surgery and research,1749799x,Springer Science and Business Media LLC,United Kingdom,Xue-Zhen Liang; Nan Li; Jin-Lian Chai; Wei Li; Di Luo; Gang Li,"Osteonecrosis of the femoral head (ONFH) is a common, refractory and disabling disease of orthopedic department, which is one of the common causes of hip pain and dysfunction. Recent studies have shown that much progress has been made in the research of programmed cell death (PCD) in ONFH. However, there is no bibliometric analysis in this research field. This study aims to provide a comprehensive overview of the knowledge structure and research hot spots of PCD in ONFH through bibliometrics.; The literature search related to ONFH and PCD was conducted on the Web of Science Core Collection (WoSCC) database from 2002 to 2021. The VOSviewers, ""bibliometrix"" R package and CiteSpace were used to conduct this bibliometric analysis.; In total, 346 articles from 27 countries led by China and USA and Japan were included. The number of publications related to PCD in ONFH is increasing year by year. Shanghai Jiao Tong University, Xi An Jiao Tong University, Wuhan University and Huazhong University of Science and Technology are the main research institutions. Molecular Medicine Reports is the most popular journal in the field of PCD in ONFH, and Clinical Orthopaedics and Related Research is the most cocited journal. These publications come from 1882 authors among which Peng Hao, Sun Wei, Zhang Chang-Qing, Zhang Jian and Wang Kun-zheng had published the most papers and Ronald S Weinstein was cocited most often. Apoptosis, osteonecrosis, osteonecrosis of the femoral head, glucocorticoid and femoral head appeared are the main topics the field of PCD in ONFH. Autophagy was most likely to be the current research hot spot for PCD in ONFH.; This is the first bibliometric study that comprehensively summarizes the research trends and developments of PCD in ONFH. This information identified recent research frontiers and hot directions, which will provide a reference for scholars studying PCD in ONFH.; © 2023. The Author(s).",18,1,864,,Femoral head; Medicine; Bibliometrics; Orthopedic surgery; Web of science; Internal medicine; Library science; Surgery; Meta-analysis; Computer science,Apoptosis; Autophagy; Bibliometrix; CiteSpace; Osteonecrosis of femoral head; Programmed cell death; VOSviewers,Humans; Femur Head; China; Apoptosis; Osteonecrosis; Bibliometrics,,National Natural Science Foundation of China (No. 82205154); National Natural Science Foundation of China (No. 82074453); National Natural Science Foundation of Shandong Province (No. ZR2021QH004); National Natural Science Foundation of Shandong Province (No. ZR2021LZY002),https://josr-online.biomedcentral.com/counter/pdf/10.1186/s13018-023-04314-2 https://doi.org/10.1186/s13018-023-04314-2,http://dx.doi.org/10.1186/s13018-023-04314-2,37957649,10.1186/s13018-023-04314-2,,PMC10644483,0,000-221-995-309-419; 000-638-349-662-027; 001-189-653-891-575; 001-570-287-440-936; 002-052-422-936-00X; 002-082-955-544-612; 002-666-937-092-72X; 003-756-009-402-233; 004-184-611-116-710; 006-971-759-197-487; 007-940-695-828-028; 011-821-577-661-610; 011-928-540-931-840; 013-507-404-965-47X; 014-726-816-008-71X; 017-231-075-291-427; 017-951-173-535-179; 018-718-169-703-390; 019-888-710-612-429; 021-026-947-431-59X; 022-254-013-951-429; 022-682-351-748-969; 023-339-894-404-212; 024-095-288-973-421; 024-943-205-734-249; 026-395-112-558-483; 026-624-617-529-115; 026-861-061-294-881; 027-434-351-401-366; 030-901-520-294-88X; 033-156-067-812-74X; 033-345-859-255-26X; 036-370-540-142-822; 038-441-595-290-660; 038-553-176-126-029; 043-659-105-417-968; 050-726-431-937-206; 050-868-898-849-967; 051-631-896-877-578; 057-353-358-328-230; 058-178-978-028-838; 058-851-867-287-471; 059-661-858-414-415; 060-802-092-621-198; 062-803-314-841-485; 065-727-605-378-934; 069-658-664-429-198; 070-320-342-702-46X; 080-749-945-686-002; 080-977-108-232-315; 082-383-996-999-008; 085-395-890-243-306; 085-883-734-627-386; 087-273-956-694-079; 090-476-872-676-699; 096-590-690-027-134; 100-017-329-039-768; 107-500-882-679-642; 109-644-089-980-70X; 111-460-809-062-858; 114-649-295-038-735; 124-662-841-540-95X; 131-975-510-958-551; 133-386-759-529-223; 167-373-519-239-682,2,true,"CC BY, CC0",gold -032-632-894-036-017,Sedimentary DNA for tracking the long-term changes in biodiversity.,2023-01-09,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Haoyu Li; Hucai Zhang; Fengqin Chang; Qi Liu; Yang Zhang; Fengwen Liu; Xiaonan Zhang,,30,7,17039,17050,Biodiversity; Scope (computer science); Ecology; Environmental resource management; Geodiversity; Environmental DNA; Ancient DNA; Earth science; Geography; Data science; Environmental science; Biology; Computer science; Geology; Sociology; Programming language; Population; Demography,Bibliometric analysis; Biodiversity; Biological dynamics; SedDNA; Sedimentary DNA,Geologic Sediments; Biodiversity; DNA; Eukaryota/genetics; Ecosystem,DNA,National Natural Science Foundation of China (41820104008); National Natural Science Foundation of China (42201172),,http://dx.doi.org/10.1007/s11356-023-25130-5,36622608,10.1007/s11356-023-25130-5,,,0,000-853-766-723-750; 001-557-303-110-819; 002-012-186-889-662; 002-373-257-730-143; 002-726-321-847-17X; 004-054-332-452-660; 004-073-340-136-194; 004-092-436-774-549; 004-213-400-622-39X; 004-288-114-128-370; 004-351-951-578-730; 004-382-597-163-103; 005-969-209-663-050; 006-046-400-510-678; 007-163-967-436-64X; 007-975-718-192-254; 008-327-462-083-935; 008-406-829-670-761; 009-240-983-744-836; 009-433-973-095-79X; 009-783-314-238-566; 009-961-690-796-093; 010-013-851-069-176; 010-194-644-590-36X; 010-469-798-902-768; 012-671-179-137-106; 013-298-517-429-878; 013-507-404-965-47X; 014-891-467-313-693; 015-391-428-686-396; 016-772-976-575-625; 016-782-759-093-899; 018-266-398-817-143; 018-659-351-903-690; 019-441-725-473-133; 020-079-047-539-063; 020-112-561-131-53X; 020-646-189-437-44X; 021-092-880-634-805; 021-641-352-742-983; 025-523-741-579-612; 027-384-205-660-420; 028-396-357-613-214; 028-472-933-901-831; 028-495-432-130-380; 028-554-579-619-516; 030-735-431-365-235; 031-633-353-060-426; 032-835-878-575-029; 033-047-055-144-489; 035-058-784-152-389; 035-320-253-551-541; 036-483-611-896-949; 041-079-432-708-187; 041-523-329-848-112; 042-725-260-310-462; 042-910-639-492-20X; 044-393-845-005-61X; 048-732-976-645-456; 049-213-649-611-306; 051-220-201-578-031; 051-334-337-272-520; 052-091-635-652-823; 053-069-529-282-668; 056-967-046-530-616; 065-507-332-917-079; 067-673-354-469-824; 069-420-153-380-863; 073-611-367-814-790; 077-315-562-932-337; 078-223-193-784-655; 080-488-817-187-804; 080-897-283-218-924; 083-633-191-821-259; 085-981-470-043-617; 086-000-260-792-076; 088-013-745-412-188; 090-742-019-135-579; 091-273-368-196-190; 092-616-197-575-476; 096-278-439-204-966; 098-020-725-645-310; 098-685-386-075-929; 100-301-229-832-37X; 103-870-722-399-273; 106-339-950-166-351; 108-677-741-983-376; 117-259-366-844-060; 121-301-690-342-741; 122-061-285-853-27X; 123-623-551-292-734; 126-618-651-014-857; 126-663-536-250-144; 131-549-870-645-688; 132-607-853-298-572; 136-781-827-118-91X; 136-889-176-188-547; 137-391-480-361-840; 137-763-030-823-395; 142-610-227-339-920; 145-973-852-399-736; 155-726-324-248-963; 162-572-881-440-063; 175-016-862-827-005; 179-261-563-858-439; 182-206-040-656-009; 189-281-757-753-054,8,false,, -032-634-191-515-600,Responsabilidad Social Universitaria: una revisión sistemática y análisis bibliométrico,2019-12-04,2019,journal article,Estudios Gerenciales,26656744; 01235923,Universidad Icesi,,Pedro Duque; Luis Salvador Cervantes Cervantes,"espanolEl proposito de este articulo es realizar una revision sistematica y un analisis bibliometrico de la produccion cientifica relacionada con la Responsabilidad Social Universitaria, a traves de una revision en las bases de datos Web of Science y Scopus. Los registros obtenidos fueron analizados empleando la teoria de grafos y herramientas como bibliometrix, Sci2 Tool y Gephi; ademas, fueron presentados en tres categorias: hegemonicos, estructurales y recientes. Los resultados permitieron identificar tres perspectivas: medicion, estrategico y conexion; tambien muestran que este campo de estudio es relativamente joven, en el cual el autor principal es Ricardo Gaete, mientras que Francois Vallaeys es el mas citado. Adicionalmente, la region de mayor produccion en el tema es Suramerica Englishhe purpose of this article is to perform a systematic review and a bibliometric analysis of the scientific production related to University Social Responsibility, by means of a review in the Web of Science and Scopus databases. The records obtained were analyzed using the graph theory and tools such as bibliometrix, Sci2 Tool, and Gephi. In addition, they were presented in three categories: hegemonic, structural, and recent. The results allowed to identify three perspectives: measurement, strategic, and connection. They also show that this field of study is relatively young, in which the principal author is Ricardo Gaete, while Francois Vallaeys is the most cited. Additionally, the region with the highest production in the subject is South Americ portuguesO objetivo deste artigo e realizar uma revisao sistematica e uma analise bibliometrica da producao cientifica relacionada a Responsabilidade Social Universitaria, atraves de uma revisao nas bases de dados Web of Science e Scopus. Os registros obtidos foram analisados utilizando a teoria dos grafos e ferramentas como bibliometrix, Sci2 Tool e Gephi; Alem disso, foram apresentados em tres categorias: hegemonicos, estruturais e recentes. Os resultados permitiram identificar tres perspectivas: mensuracao, estrategica e conexao; Mostram tambem que esse campo de estudo e relativamente jovem, em que o autor principal e Ricardo Gaete, enquanto Francois Vallaeys e o mais citado. Alem disso, a regiao com maior producao no assunto e a America do Sul",35,153,451,464,,,,,,https://dialnet.unirioja.es/descarga/articulo/7504670.pdf http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0123-59232019000400451 https://dialnet.unirioja.es/servlet/articulo?codigo=7504670 https://repository.icesi.edu.co/biblioteca_digital/handle/10906/85253 http://www.scielo.org.co/pdf/eg/v35n153/0123-5923-eg-35-153-451.pdf https://core.ac.uk/download/pdf/276541617.pdf,http://dx.doi.org/10.18046/j.estger.2019.153.3389,,10.18046/j.estger.2019.153.3389,2995632952,,0,,55,true,cc-by,gold -032-777-667-042-780,"Social Entrepreneurship, Value Creation, and Sustainability",2022-05-27,2022,book chapter,"Advances in Logistics, Operations, and Management Science",2327350x; 23273518,IGI Global,,Raihan Taqui Syed; Dharmendra Singh; David Philip Spicer,"This chapter presents an in-depth examination and analysis of published literature indexed in Scopus database on social entrepreneurship, sustainability, and value creation. A descriptive bibliometric analysis coupled with content analysis is presented incorporating citations included in Scopus' multi-disciplinary database over the last 20 years. Two software packages, VOS Viewer and Bibliometrix R, were employed to probe the research questions and create visualizations of the bibliometric networks. The interconnected and multifaceted nature of the research field is demonstrated, thematic evolution is illustrated, and emerging clusters are identified. Findings suggest that the research on social entrepreneurship, sustainability, and value creation has been pioneered by USA followed by India and other countries. Also, further steps need to be undertaken to encourage and enable cross-border international collaboration to draw learning together from different national and regional contexts. ",,,1,18,Scopus; Sustainability; Entrepreneurship; Thematic analysis; Discipline; Value (mathematics); Knowledge management; Field (mathematics); Value creation; Social network analysis; Content analysis; Regional science; Political science; Social capital; Data science; Sociology; Social science; Qualitative research; Computer science; Ecology; Mathematics; MEDLINE; Machine learning; Pure mathematics; Law; Biology,,,,,,http://dx.doi.org/10.4018/978-1-6684-4666-9.ch001,,10.4018/978-1-6684-4666-9.ch001,,,0,004-165-766-721-911; 008-503-021-110-600; 010-091-998-488-563; 013-422-282-868-950; 013-507-404-965-47X; 019-699-637-726-16X; 019-848-752-466-128; 020-095-383-008-392; 023-527-718-075-323; 025-613-233-950-568; 032-161-831-571-882; 033-014-253-880-814; 034-245-699-998-862; 034-848-852-823-034; 039-101-432-893-817; 043-978-415-056-502; 044-273-117-734-340; 063-923-109-075-518; 064-319-450-193-281; 075-216-272-257-429; 075-636-596-178-023; 076-048-730-218-555; 076-362-237-070-679; 077-235-952-619-805; 079-746-444-437-105; 082-981-095-520-012; 087-039-175-403-499; 087-880-193-343-581; 091-665-851-820-988; 093-079-508-738-670; 093-122-684-921-168; 094-996-584-032-447; 109-214-920-628-164; 111-348-209-308-455; 116-545-813-640-686; 123-380-982-614-72X; 130-602-202-936-694; 138-856-335-101-827; 139-364-430-420-645; 140-176-565-691-036; 164-566-134-146-268; 176-753-588-630-192; 183-158-161-350-500; 192-135-671-580-685,1,false,, -033-302-641-036-160,A keystroke analysis to study writing: a bibliometric review using R and VOSviewer,2024-09-30,2024,journal article,RESEARCH RESULT Theoretical and Applied Linguistics,23138912,Belgorod National Research University,,Olga V. Dekhnich; Tatyana A. Litvinova,"Data obtained by means of keystroke logging software, which records all writing events, i.e., all keypresses with their time stamps, are widely used in different research fields and practical applications – from early detection of cognitive impairments to user authentication. Keystroke logging software have become especially popular in writing studies since it allows researchers to observe writing processes unobtrusively and increases their understanding of what happens “behind the scenes” of text production. This methodology has been used in writing studies since the advent of affordable computers in the 1990s, however, there has still been no bibliometric review that would provide a holistic picture of this field and identify hot topics and trends, perform citation analysis and identify the most productive authors and countries in the field of writing research using keystroke data. This paper is pioneer research to conducting a bibliometric analysis on the field “keystroke analysis to study writing” aimed at filling in the gap. A search was conducted in the bibliographic database Scopus on July 11, 2024. We included studies published in English post-2000 that discuss the use of keystroke data and methodology to study writing process. This review followed the guidelines of the PRISMA protocol to perform the study search and selection. The search yielded 336 documents of which 273 met out inclusion criteria. The records retrieved were analysed using the bibliometrix R-package and VOSviewer software. Using these tools in combinations, we implemented both performance analysis which examines the contributions of research constituents to a given field and science mapping which is aimed at revealing the relationships between research constituents. The contribution of this study is twofold. Firstly, it provides an in-depth bibliometric analysis of an actively developing field of research which is rather limited in terms osf the countries and institutions involved (and the languages of the texts analysed), hopefully saving time and effort for researchers new to the field. Secondly, we provide an example of using bibliometrix and VOSviewer for a bibliometric analysis which could be easily replicated in further research.",10,3,,,Keystroke logging; Computer science; Data science; Psychology; Computer security,,,,,,http://dx.doi.org/10.18413/2313-8912-2024-10-3-0-5,,10.18413/2313-8912-2024-10-3-0-5,,,0,,0,true,,bronze -033-398-764-802-24X,Science mapping for radiation shielding research,,2021,journal article,Radiation Physics and Chemistry,0969806x,Elsevier BV,United Kingdom,Ozge Kilicoglu; Hakan Mehmetcik,,189,,109721,,Publishing; Political science; Order (exchange); Data science; Country of origin; Quality (business); R package; Science mapping; Radiation shielding; Field (computer science),,,,,https://www.sciencedirect.com/science/article/pii/S0969806X21003716 https://avesis.marmara.edu.tr/yayin/a123ff1d-6219-4c20-a701-8e69215d8d7f/science-mapping-for-radiation-shielding-research,http://dx.doi.org/10.1016/j.radphyschem.2021.109721,,10.1016/j.radphyschem.2021.109721,3183633869,,0,002-889-632-858-980; 013-507-404-965-47X; 023-593-226-606-605; 034-768-039-318-254; 035-749-586-058-159; 038-127-090-782-904; 042-223-486-427-479; 048-823-283-439-821; 075-797-616-030-817; 083-219-259-466-22X; 096-995-623-959-359; 105-999-580-311-036; 106-598-824-898-46X; 126-414-936-681-712; 150-646-319-619-692; 161-793-988-949-372,33,false,, -033-755-041-647-285,"Software survey: ScientoPy, a scientometric tool for topics trend analysis in scientific publications",2019-08-30,2019,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Juan Ruiz-Rosero; Gustavo Ramirez-Gonzalez; Jesus Viveros-Delgado,,121,2,1165,1188,Trend analysis; Set (abstract data type); Bibliometrics; Data science; Software; Computer science; Scientometrics; Thematic analysis; Internet of Things; Scopus,,,,"Departamento Administrativo de Ciencia, Tecnología e Innovación",https://link.springer.com/article/10.1007/s11192-019-03213-w https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics121.html#Ruiz-RoseroGV19 http://dblp.uni-trier.de/db/journals/scientometrics/scientometrics121.html#Ruiz-RoseroGV19 https://ideas.repec.org/a/spr/scient/v121y2019i2d10.1007_s11192-019-03213-w.html,http://dx.doi.org/10.1007/s11192-019-03213-w,,10.1007/s11192-019-03213-w,2971022377,,0,000-519-104-630-201; 002-052-422-936-00X; 003-110-646-998-807; 006-461-237-333-939; 009-630-640-690-243; 013-507-404-965-47X; 013-524-854-219-241; 023-841-019-437-52X; 027-085-212-936-026; 034-658-158-500-326; 035-267-812-184-398; 036-926-607-615-796; 037-920-218-715-055; 047-134-478-431-993; 060-110-039-971-60X; 064-400-499-357-900; 076-173-750-988-541; 082-154-339-780-779; 106-831-281-915-70X; 111-688-410-413-952; 120-040-246-058-26X; 122-586-674-413-659; 154-958-212-177-335; 178-339-503-180-911,124,false,, -034-191-271-540-34X,The Impacts of Bibliometrics Measurement in the Scientific Community A Statistical Analysis of Multiple Case Studies,2022-07-12,2022,journal article,Review of European Studies,19187181; 19187173,Canadian Center of Science and Education,Canada,Vincenzo Basile; Massimiliano Giacalone; Paolo Carmelo Cozzucoli,"In recent years, statistical methods such as bibliometrics have increasingly intensified to analyse books, articles, and other publications. Bibliometric methods, as techniques to measure the information distribution models, are frequently used in the field of information science and social research. The main purpose of this article is to offer scholars a general framework for the comparison between positive and negative aspects of bibliometrics, on the methods and tools used. Therefore, both the strengths and the critical points will be highlighted, to obtain a complete and detailed overview of the entire argument. In the methodological part, a bibliometric analysis will be applied to various case studies, such as with the Generalized Error Distribution, analysing and commenting on the data, and using the Bibliometrix software. The results suggest that in the future there will be greater consolidation of bibliometrics, as the introduction of increasingly advanced technologies will create new tools and methods characterized by a high degree of automation and speed.",14,3,10,10,Bibliometrics; Data science; Computer science; Field (mathematics); Consolidation (business); Management science; Data mining; Mathematics; Engineering; Economics; Accounting; Pure mathematics,,,,,https://ccsenet.org/journal/index.php/res/article/download/0/0/47484/51166 https://doi.org/10.5539/res.v14n3p10,http://dx.doi.org/10.5539/res.v14n3p10,,10.5539/res.v14n3p10,,,0,,7,true,,gold -034-301-984-933-965,Unveiling a century of Taraxacum officinale G.H. Weber ex Wiggers research: a scientometric analysis and thematically-based narrative review,2024-04-05,2024,journal article,Bulletin of the National Research Centre,25228307,Springer Science and Business Media LLC,,Manal Mohamed Elhassan Taha; Siddig Ibrahim Abdelwahab,"Abstract; Background; This study aims to conduct a scientometric analysis and thematically-based narrative review of a century of Taraxacum officinale research (TOR), uncovering patterns, trends, themes, and advancements in the field to provide insights for future investigations. The study followed PRISMA guidelines and utilized the Scopus database with MeSH terms for bibliographic data retrieval. Scientometric mapping employed VOSviewer and R-package-based Bibliometrix, while extracted themes were reviewed narratively. A detailed analysis of TOR was achieved by including only original studies.; ; Results; The findings include the extensive duration of TOR since 1908 and its significant growth, particularly in the last two decades. China emerges as the most productive country, but the United States leads in recognizable and collaborative TOR. The thematic map displays dynamic and diverse themes, with a rich knowledge structure revealed through the analysis of term co-occurrence. The year 2016 represents a turning point in the thematic map, marked by numerical growth and thematic bifurcation. The study extracted several main research topics within the field of TOR, including germination, antioxidant activity, bioherbicide, oxidative stress, Taraxacum kok-saghyz, and heavy metals. These topics represent key areas of investigation and provide insights into the diverse aspects of research surrounding T. officinale. Additionally, emerging topics in TOR encompass toxicity, metabolomics, dandelion extract, and diabetes mellitus.; ; Conclusions; The study consolidated knowledge, highlighted research gaps, and provided directions for future investigations on TOR.; ",48,1,,,Taraxacum officinale; Thematic analysis; Dandelion; Narrative; Scopus; Narrative inquiry; Library science; Sociology; Political science; Social science; Computer science; Qualitative research; Literature; Medicine; MEDLINE; Art; Alternative medicine; Pathology; Traditional Chinese medicine; Law,,,,Jazan University,https://bnrc.springeropen.com/counter/pdf/10.1186/s42269-024-01194-2 https://doi.org/10.1186/s42269-024-01194-2,http://dx.doi.org/10.1186/s42269-024-01194-2,,10.1186/s42269-024-01194-2,,,0,000-542-598-863-94X; 000-667-231-896-402; 002-348-963-549-734; 002-580-972-898-457; 002-987-947-658-528; 004-316-912-760-851; 004-769-268-033-996; 005-776-174-383-823; 005-821-274-342-391; 006-528-152-404-172; 006-622-659-614-217; 008-346-333-571-506; 008-878-336-625-861; 009-155-014-918-79X; 011-595-395-038-171; 014-259-701-886-985; 014-556-828-790-105; 014-955-059-462-833; 015-770-521-570-742; 016-074-569-178-472; 016-586-465-277-109; 016-716-853-672-787; 016-888-486-571-60X; 019-306-669-298-315; 020-211-421-981-202; 020-396-431-249-895; 020-408-934-053-398; 024-095-304-512-044; 024-345-469-563-236; 027-543-644-178-359; 029-017-014-588-022; 031-844-883-009-652; 033-243-659-566-082; 037-667-086-643-523; 040-627-171-926-618; 041-884-319-311-278; 045-347-839-723-139; 046-992-864-415-70X; 054-159-894-171-769; 055-986-874-014-091; 056-640-593-740-650; 058-228-182-896-210; 058-840-826-995-902; 060-199-607-107-793; 060-500-106-524-812; 061-835-790-570-858; 062-155-633-906-036; 064-428-505-611-923; 066-996-972-653-194; 067-071-490-889-155; 067-477-969-205-907; 068-695-339-607-401; 069-017-353-987-723; 070-674-196-332-592; 070-922-737-697-384; 071-679-345-840-718; 072-573-933-440-631; 075-394-835-502-689; 079-556-551-107-665; 080-301-332-297-076; 081-288-063-425-238; 082-566-188-528-891; 083-643-393-955-879; 089-020-664-831-112; 099-071-967-717-838; 108-347-685-135-265; 113-354-200-693-821; 117-764-099-228-219; 119-236-289-214-540; 129-066-974-289-392; 131-058-071-028-61X; 140-786-895-881-623; 143-957-041-205-552; 149-964-243-191-340; 156-608-716-418-000; 157-818-557-396-618; 158-395-872-228-619; 163-988-188-213-570; 172-945-763-951-649; 174-537-742-292-744; 191-936-121-722-400; 192-919-137-314-219; 198-269-360-752-111; 199-570-917-146-039; 199-748-032-306-731,0,true,cc-by,gold -034-365-565-890-625,The bibliometric analysis of research on traditional Chinese medicine regulating gut microbiota for cancer treatment from 2014 to 2024.,2025-06-03,2025,journal article,Hereditas,16015223; 00180661,Springer Science and Business Media LLC,Germany,Youfeng Lei; Yueqin Shan; Danfeng Zhou; Chunyan Chen,"The modulation of gut microbiota by Traditional Chinese Medicine (TCM) offers a promising approach to cancer treatment. However, a comprehensive bibliometric evaluation of this emerging field is lacking.; This study aimed to systematically analyze global research trends, hotspots, and future directions related to TCM regulation of gut microbiota in cancer therapy from 2014 to 2024.; Publications were retrieved from the Web of Science Core Collection. Bibliometric and visual analyses were conducted using VOSviewer and CiteSpace to examine publication trends, country and institutional collaborations, core authors and journals, keyword co-occurrence, and research frontiers.; A total of 340 relevant articles were identified. The number of publications increased significantly after 2018, indicating growing interest in this field. China dominated the research landscape, both in productivity and institutional collaboration. Core research hotspots included ""short-chain fatty acids,"" ""tumor microenvironment,"" ""apoptosis,"" and ""immune response."" Thematic evolution analysis highlighted a shift from general gut microbiota research to precise molecular mechanisms and targeted regulation. Emerging topics such as ""metabolomics"" and ""immune checkpoint blockade"" suggest future directions.; This study provides a comprehensive overview of the current research landscape on TCM-modulated gut microbiota in cancer treatment. By identifying core contributors, research hotspots, and frontiers, it offers valuable guidance for future investigations and interdisciplinary collaborations in this promising field.; © 2025. The Author(s).",162,1,94,,,Bibliometric; Cancer; Cancer treatment; Gut microbiota; Traditional Chinese medicine,"Gastrointestinal Microbiome/drug effects; Humans; Neoplasms/therapy; Bibliometrics; Medicine, Chinese Traditional",,,,http://dx.doi.org/10.1186/s41065-025-00456-x,40462156,10.1186/s41065-025-00456-x,,PMC12131599,0,001-132-960-644-745; 004-391-862-345-122; 005-120-657-081-836; 005-753-396-106-184; 006-597-326-200-137; 007-431-558-965-354; 007-972-781-398-841; 008-557-764-306-165; 009-903-172-440-42X; 011-962-789-256-587; 015-325-661-276-793; 016-484-674-816-124; 020-633-142-196-72X; 021-120-360-704-975; 021-228-173-233-383; 027-820-240-651-819; 029-430-123-515-147; 030-809-997-268-687; 032-347-382-015-391; 032-571-125-541-936; 039-871-157-237-743; 044-444-812-527-531; 045-125-085-721-01X; 046-608-824-344-426; 048-046-420-424-818; 048-828-460-338-144; 051-434-289-146-922; 053-202-662-148-855; 054-301-095-781-75X; 057-086-104-784-355; 058-145-520-914-706; 059-615-047-416-663; 062-546-087-533-428; 063-382-259-895-977; 067-149-367-102-30X; 067-366-327-928-159; 069-606-278-560-628; 071-595-920-572-484; 079-985-104-758-859; 082-173-838-814-359; 083-058-969-437-971; 087-160-306-911-480; 088-189-525-267-280; 092-062-550-269-321; 094-783-176-839-912; 094-959-155-989-117; 095-909-342-803-382; 099-575-203-783-666; 100-915-525-808-573; 101-313-038-402-064; 101-380-705-332-080; 101-866-947-838-519; 106-317-590-125-494; 111-895-509-521-859; 113-332-422-481-544; 113-448-023-764-541; 115-828-871-606-033; 117-565-095-340-076; 119-601-123-198-424; 120-800-212-428-751; 125-915-127-715-58X; 138-556-748-665-036; 147-164-698-750-665; 148-235-796-639-444; 149-070-756-054-250; 150-149-045-036-280; 155-671-493-873-190; 158-314-536-897-779; 188-635-844-283-192; 193-869-495-175-611; 195-479-141-165-212,0,true,"CC BY, CC0",gold -034-369-912-514-367,Coastal cliff erosion: a bibliometric analysis and literature review,2025-03-06,2025,journal article,Anthropocene Coasts,25614150,Springer Science and Business Media LLC,,Sibila A. Genchi; Alejandro J. Vitale; Gerardo M. E. Perillo,"Abstract; Cliffed (and rocky) coasts are geomorphic features occurring in about 80% of the coastline of the world and are strongly influenced by a broad range of both natural and anthropogenic processes that may cause serious erosion problems. Since the sea wave motion is a fundamental driver of cliff erosion, the cliffs become sensitive to increasing of global sea levels and to extreme weather events, which are both associated with global warming. Because of its importance, a considerable amount of investigations on coastal cliff erosion (CCE) were reported during the last decades. A bibliometric analysis is an useful tool to identify patterns of a given theme from a large body of academic literature. There is no previous evidence of a global bibliometric analysis in the literature in English on themes of CCE. Therefore, the aim of this article was to carry out a bibliometric analysis from Scopus database of CCE for the period 2000–2023. Once obtained, two filtering steps for selection of documents consisting of a custom R script implementation and a careful reading of the remaining documents were applied. During the search, a dynamic approach that puts emphasis on the processes operating on rocky coasts was selected instead of an evolutionary geological perspective. The final list reached 583 documents. A second aim was to discuss the research trends and challenges based on the latest highly-cited documents. As main result, the trend of the scientific production in the theme of CCE had an increasing interest over the last years, with an average compound annual growth rate of 15.6%. On the other side, the results demonstrated that even though the USA took the second place, European countries (United Kingdom, Italy, France, Portugal, Spain and Poland) lead the ranking; therefore, there is a scarcity of knowledge about the theme in large regions such as South America and Africa where seacliffs are dominants.",8,1,,,Cliff; Coastal erosion; Erosion; Geography; Geology; Physical geography; Archaeology; Geomorphology,,,,,,http://dx.doi.org/10.1007/s44218-025-00072-2,,10.1007/s44218-025-00072-2,,,0,000-433-115-524-095; 000-461-603-756-424; 000-600-859-004-485; 000-633-338-219-406; 003-459-622-397-89X; 004-158-644-113-736; 007-849-196-561-448; 008-144-699-188-856; 008-407-588-074-292; 011-115-868-004-532; 012-145-939-838-408; 012-648-995-776-20X; 013-507-404-965-47X; 013-943-659-357-960; 014-229-782-218-913; 015-522-341-294-426; 015-605-977-723-349; 017-387-596-600-345; 020-181-265-582-810; 020-333-658-816-892; 020-717-397-637-185; 020-847-008-879-275; 023-233-533-650-658; 023-580-809-453-011; 024-696-066-163-232; 025-454-652-190-465; 028-538-377-044-136; 028-652-020-211-084; 033-199-532-640-008; 033-765-573-033-865; 034-150-169-697-411; 034-372-959-063-513; 036-301-236-633-169; 036-443-276-164-671; 038-275-485-607-224; 040-349-802-032-77X; 043-736-097-165-09X; 044-277-405-621-955; 048-568-561-353-396; 049-253-312-367-690; 060-309-125-807-847; 065-863-883-855-303; 067-030-816-337-748; 067-120-261-026-258; 069-884-753-338-04X; 071-567-632-061-155; 073-233-227-604-26X; 073-438-811-490-555; 074-473-632-503-437; 075-297-562-544-650; 080-517-933-686-723; 083-047-236-129-214; 085-407-729-814-868; 088-983-274-762-911; 091-630-634-012-95X; 094-461-403-400-909; 096-349-539-725-123; 098-680-989-449-747; 109-243-192-285-687; 109-583-988-068-486; 110-252-507-774-283; 115-844-654-090-771; 116-439-647-168-136; 117-209-155-428-66X; 137-429-247-837-516; 146-091-610-060-790; 149-072-561-653-949; 151-680-526-078-644; 153-326-572-959-507; 156-643-027-769-546; 156-776-754-145-464; 157-210-691-626-650; 160-318-220-425-687; 160-810-655-120-481; 177-702-735-225-557; 179-847-479-691-259; 182-865-235-643-127,0,true,cc-by,hybrid -034-572-246-860-332,"Examining the research taxonomy of artificial intelligence, deep learning & machine learning in the financial sphere-a bibliometric analysis.",2023-05-02,2023,journal article,Quality & quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Ajitha Kumari Vijayappan Nair Biju; Ann Susan Thomas; J Thasneem,"This paper surveys the extant literature on machine learning, artificial intelligence, and deep learning mechanisms within the financial sphere using bibliometric methods. We considered the conceptual and social structure of publications in ML, AI, and DL in finance to better understand the research's status, development, and growth. The study finds an upsurge in publication trends within this research arena, with a bit of concentration around the financial domain. The institutional contributions from USA and China constitute much of the literature on applying ML and AI in finance. Our analysis identifies emerging research themes, with the most futuristic being ESG scoring using ML and AI. However, we find there is a lack of empirical academic research with a critical appraisal of these algorithmic-based advanced automated financial technologies. There are severe pitfalls in the prediction process using ML and AI due to algorithmic biases, mostly in the areas of insurance, credit scoring and mortgages. Thus, this study indicates the next evolution of ML and DL archetypes in the economic sphere and the need for a strategic turnaround in academics regarding these forces of disruption and innovation that are shaping the future of finance.",58,1,1,878,Archetype; Artificial intelligence; Extant taxon; Empirical research; Social sphere; Finance; Zhàng; Machine learning; China; Sociology; Computer science; Economics; Political science; Social science; Mathematics; Statistics; Art; Literature; Evolutionary biology; Law; Biology,Artificial intelligence; Bibliometric analysis; Conceptual structure; Deep learning; Machine learning; Social structure,,,,https://link.springer.com/content/pdf/10.1007/s11135-023-01673-0.pdf https://doi.org/10.1007/s11135-023-01673-0,http://dx.doi.org/10.1007/s11135-023-01673-0,37359968,10.1007/s11135-023-01673-0,,PMC10153784,0,000-209-316-822-172; 000-224-939-167-210; 001-004-221-502-966; 002-307-227-235-429; 003-118-998-063-278; 003-207-870-921-565; 003-873-128-301-470; 004-239-413-234-842; 004-585-104-936-279; 006-453-610-493-261; 007-149-395-215-786; 008-307-044-940-043; 008-457-519-007-462; 009-340-549-846-256; 010-495-710-613-419; 012-134-492-216-464; 013-507-404-965-47X; 013-604-079-687-22X; 014-183-372-850-982; 015-692-170-714-052; 016-996-088-518-086; 017-009-949-927-506; 018-799-120-647-081; 019-480-435-924-719; 019-976-993-060-379; 020-966-846-063-365; 022-054-272-396-697; 022-914-472-325-057; 023-089-055-846-846; 023-660-095-863-018; 024-723-551-536-419; 032-117-169-875-647; 032-253-675-102-889; 032-677-286-156-639; 033-863-890-428-413; 034-542-345-839-881; 034-768-039-318-254; 035-480-473-440-563; 035-953-579-141-278; 036-665-842-111-878; 037-029-897-660-670; 039-198-286-388-356; 045-000-053-889-943; 045-189-186-712-502; 050-623-270-109-204; 054-159-894-171-769; 055-767-313-883-449; 057-015-074-359-471; 057-864-131-604-151; 058-655-663-273-184; 058-978-861-755-439; 059-149-073-001-124; 059-507-729-500-979; 059-955-372-592-354; 062-342-641-200-336; 063-847-261-885-214; 064-216-005-051-777; 068-222-300-264-181; 071-852-294-541-545; 071-878-836-294-733; 072-185-127-884-508; 073-413-328-692-885; 078-514-335-507-275; 079-787-756-707-419; 082-098-411-785-66X; 082-817-330-342-566; 086-908-226-893-99X; 089-174-953-588-819; 089-389-668-851-591; 089-751-234-475-049; 096-282-873-638-910; 100-677-169-613-68X; 103-056-286-274-012; 111-609-139-641-094; 111-796-372-189-379; 112-442-570-513-895; 112-705-069-209-103; 113-782-170-639-584; 114-352-973-897-348; 118-308-401-320-84X; 120-714-827-303-807; 120-885-678-404-810; 122-280-834-204-142; 123-515-810-737-366; 125-531-153-078-569; 129-082-381-303-697; 129-762-849-312-126; 133-601-998-373-261; 138-637-385-409-141; 141-200-607-894-303; 143-478-097-848-831; 143-936-693-364-687; 146-632-461-452-481; 147-023-625-223-646; 149-379-495-957-704; 150-467-309-378-385; 152-984-024-916-635; 154-234-647-000-084; 156-093-829-440-191; 160-459-271-777-091; 165-052-353-763-133; 175-239-069-606-678; 176-139-503-472-798; 178-578-622-737-477,45,true,,bronze -034-764-479-843-767,Generational Gaps and Nursing Education: A Bibliometric Analysis from 1968 to 2021,2024-07-22,2024,preprint,,,MDPI AG,,Paula Yanira Palencia,"The objective of this research was to analyze the evolution and trend of the generation gap and nursing education from 1968 to 2021 through bibliometric indicators. The method used is a bibliometric, descriptive and retrospective study of documents in Scopus, with descriptors &ldquo;Nursing educat*&rdquo;, &ldquo;generation* and the Boolean operator &ldquo;AND&rdquo;, N= 653 web documents from 1968 to 2021, and filters of the type bib, csv. The search was carried out on October 9, 2021, using the Bibliometrix R Package software and the Biblioshiny tool. The Results indicate high scientific production in 2020 (54 articles disclosed). This study demonstrates patterns and lines of research in nursing education, such as educational models, interpersonal relationships, and organizational innovation.",,,,,Scopus; Bibliometrics; Higher education; Nurse education; Nursing; Knowledge management; MEDLINE; Computer science; Library science; Medicine; Political science; Law,,,,,,http://dx.doi.org/10.20944/preprints202407.1659.v1,,10.20944/preprints202407.1659.v1,,,0,,0,true,,green -035-008-547-514-176,Knowledge landscapes and emerging trends of cardiorenal syndrome type 4: a bibliometrics and visual analysis from 2004 to 2022.,2023-07-09,2023,journal article,International urology and nephrology,15732584; 03011623,Springer Science and Business Media LLC,Netherlands,Han Li; Tongtong Liu; Liping Yang; Fang Ma; Yuyang Wang; Yongli Zhan; Huimin Mao,"To evaluate the key topics and emerging trends in the field of cardiorenal syndrome type 4 (CRS-4) by bibliometrics and visual analysis.; Citespace, VOSviewer, and Bibliometrix package were used to analyze the collected data from the Web of Science Core Collection, including publication trends, leading countries, active authors and institutions, co-cited references, journals, and keyword analysis.; Finally, 2267 articles were obtained. From 2004 to 2022, the number of publications was increasing year by year. A total of 735 authors from 543 institutions in 94 countries/regions participated in the publication of CRS-4 field, which were mostly from North America and Europe. Most of the co-cited references were reviews or guidelines from kidney/heart specialist journals or top journals. The journals concerning nephrology had a higher academic influence in this field. Oxidative stress and inflammation remained hot topics in CRS-4 research, as well as uremic toxins. Fibroblast growth factor 23 and klotho were emerging trends in recent years. Sodium glucose cotransporter 2 (SGLT2) inhibitors were the latest frontier hot spots. Future research advances may pay more attention to the prevention and prognosis assessment of CRS-4.; Our study provides some key information for scholars to determine the direction of future research.; © 2023. The Author(s).",56,1,155,166,Bibliometrics; Medicine; Web of science; Nephrology; Original research; Impact factor; Library science; Internal medicine; Political science; Meta-analysis; Computer science; Law,Bibliometric analysis; Bibliometrix; Cardiorenal syndrome type 4; CiteSpace; VOSviewer,Humans; Cardio-Renal Syndrome/therapy; Bibliometrics; Kidney; Heart; Europe,,the Scientific and technological innovation project of Chinese Academy of Traditional Chinese Medicine (CI2021A01210); the Fundamental Research Funds for the Central public welfare research institutes (ZZ13-YQ-031); the Grants from National Nature Science Foundation of China (82074393),https://link.springer.com/content/pdf/10.1007/s11255-023-03680-4.pdf https://doi.org/10.1007/s11255-023-03680-4,http://dx.doi.org/10.1007/s11255-023-03680-4,37422767,10.1007/s11255-023-03680-4,,PMC10776493,0,000-680-974-900-51X; 002-052-422-936-00X; 007-218-761-119-265; 007-500-155-247-91X; 009-804-343-549-590; 010-066-209-882-046; 012-016-091-129-16X; 013-507-404-965-47X; 017-358-353-462-651; 017-603-817-779-726; 018-848-936-336-516; 021-430-551-242-404; 025-354-690-896-073; 025-391-819-127-770; 025-714-785-759-537; 025-949-220-831-315; 027-266-877-850-908; 028-344-021-381-734; 035-646-980-108-669; 036-656-168-693-890; 044-842-314-504-795; 047-161-361-283-724; 048-288-353-033-404; 052-106-708-073-283; 054-535-693-112-216; 056-027-405-574-662; 057-257-819-238-183; 057-731-228-823-466; 060-803-663-964-747; 067-211-108-166-274; 071-097-370-010-599; 077-095-130-823-792; 077-403-702-239-666; 087-744-358-084-72X; 087-954-375-177-405; 094-715-807-100-176; 116-328-348-491-396; 145-304-040-024-375,2,true,cc-by,hybrid -035-040-551-506-953,Artificial Intelligence and Islam: A Bibiliometric-Thematic Analysis and Future Research Direction,2025-05-02,2025,journal article,Semarak International Journal of Machine Learning,30305241,Akademia Baru Publishing,,Azizan Morshidi; Noor Syakirah Zakaria; Mohammad Ikhram Mohammad Ridzuan; Rizal Zamani Idris; Azueryn Annatassia Dania Aqeela; Mohamad Shaukhi Mohd Radzi,"The present study examines the growing relationship between Artificial Intelligence (AI) and Islam. This analysis underscores the significance of investigating scholarly output in this field using bibliometric analysis. The study employs the Bibliometrix and Biblioshiny tools to demonstrate the diverse applications of AI in Islamic contexts and the challenges and opportunities that have arisen as a result of the COVID 19 pandemic. Furthermore, it emphasises the need for additional research to explore trends, key contributors, research themes, and future agendas in AI- Islam studies. Since the onset of the COVID 19 pandemic, there has been a noticeable shift in research focus towards AI-Islam, resulting in the emergence of four distinct niches: AI in education, Islamic banking, mobile banking, and Islamic ethics. Researchers are exploring the potential of AI tools in education, investigating the application of AI in Islamic banking, grappling with challenges and opportunities in mobile banking, and scrutinising the ethical implications of AI in the Islamic context.",1,1,41,58,Islam; Thematic map; Sociology; Artificial intelligence; Computer science; Geography; Philosophy; Cartography; Theology,,,,,,http://dx.doi.org/10.37934/sijml.1.1.4158a,,10.37934/sijml.1.1.4158a,,,0,,0,false,, -035-288-081-320-431,An Altmetric Analysis of Top Journals in Library and Information Science,,2019,,,,,,Rangaswamy Buddayya; Rajendra Babu H,"The paper examines the citations as well as altmetrics attention score of five Library and Information Science journals indexed by Google Scholar Metrics 2019. The study results revealed that JAIS&T journal got 1st position with h5-Index. it was also found that mostly used altmetrics source in LIS research was Mendeley (1998), followed by Twitter (113) and Blog (6) respectively. The highest altmetrics presence was seen in this study “Bibliometrix: An R-tool for Comprehensive Science Mapping Analysis” article with (50) Altmetrics Attention Score.",,,,,Sociology; Library science; Altmetrics; Science mapping,,,,,http://eprints.rclis.org/41911/,http://eprints.rclis.org/41911/,,,3167885405,,0,,0,false,, -035-384-545-578-327,Évaluation Des Performances Des Étudiants À L'Aide De L'Apprentissage Automatique : Une Étude Bibliométrique,2023-01-01,2023,preprint,,,Elsevier BV,,Michel HOUNTONDJI; Pélagie HOUNGUE; Théophile DAGBA,,,,,,Political science,,,,,,http://dx.doi.org/10.2139/ssrn.4562316,,10.2139/ssrn.4562316,,,0,013-415-445-278-408; 013-507-404-965-47X; 017-864-067-241-518; 022-440-736-915-447; 024-007-621-748-218; 032-511-896-823-240; 036-032-944-364-251; 040-486-989-588-719; 045-358-899-909-30X; 071-217-751-444-52X; 072-514-538-494-517; 080-977-108-232-315; 084-196-030-348-695; 091-847-502-195-464; 096-242-921-513-746; 096-484-077-273-602; 109-649-195-258-393; 166-210-006-970-661; 183-881-942-244-885; 192-650-458-972-731,0,false,, -035-494-239-461-734,20 Years of Particle Swarm Optimization Strategies for the Vehicle Routing Problem: A Bibliometric Analysis,2022-10-06,2022,journal article,Mathematics,22277390,MDPI AG,,Samuel Reong; Hui-Ming Wee; Yu-Lin Hsiao,"This study uses bibliometric analysis to examine the scientific evolution of particle swarm optimization (PSO) for the vehicle routing problem (VRP) over the past 20 years. Analyses were conducted to discover and characterize emerging trends in the research related to these topics and to examine the relationships between key publications. Through queries of the Web of Science and Scopus databases, the metadata for these particle swarm optimization (PSO) and vehicle routing problem (VRP) solution strategies were compared using bibliographic coupling and co-citation analysis using the Bibliometrix R software package, and secondly with VOSViewer. The bibliometric study’s purpose was to identify the most relevant thematic clusters and publications where PSO and VRP research intersect. The findings of this study can guide future VRP research and underscore the importance of developing effective PSO metaheuristics.",10,19,3669,3669,Vehicle routing problem; Particle swarm optimization; Metaheuristic; Computer science; Scopus; Metadata; Citation; Data science; Operations research; Routing (electronic design automation); Engineering; World Wide Web; Artificial intelligence; Biology; MEDLINE; Machine learning; Computer network; Biochemistry,,,,,https://www.mdpi.com/2227-7390/10/19/3669/pdf?version=1665065784 https://doi.org/10.3390/math10193669,http://dx.doi.org/10.3390/math10193669,,10.3390/math10193669,,,0,003-090-467-837-957; 004-835-507-803-517; 005-777-078-419-173; 008-634-773-308-150; 009-236-024-292-852; 013-507-404-965-47X; 013-524-854-219-241; 014-112-569-698-760; 016-117-216-588-035; 019-883-190-043-37X; 022-174-958-968-430; 023-927-221-065-800; 025-544-418-340-073; 027-653-180-255-367; 027-803-022-814-777; 028-576-052-528-48X; 030-225-948-847-261; 036-727-356-109-300; 037-441-279-951-571; 043-510-179-120-416; 044-692-013-746-941; 045-187-004-869-746; 047-741-284-287-318; 047-894-452-219-283; 052-654-930-032-738; 052-720-547-701-620; 054-818-565-070-154; 064-446-265-548-740; 066-808-219-190-598; 068-027-191-638-717; 068-916-638-850-088; 076-329-508-824-918; 078-846-440-162-353; 086-195-267-025-999; 088-432-077-428-729; 091-909-230-599-449; 097-210-468-487-390; 100-540-213-366-405; 101-752-490-869-458; 103-678-671-769-253; 103-730-074-562-006; 104-756-477-034-795; 104-916-354-894-867; 111-937-754-084-27X; 117-354-132-638-34X; 120-271-748-897-539; 132-375-580-989-510; 135-321-078-805-320; 139-901-233-595-80X; 141-200-607-894-303; 145-328-094-456-049; 164-955-943-488-734; 164-990-713-058-767; 166-170-555-211-410; 183-919-811-687-011,6,true,cc-by,gold -035-656-888-769-842,Research Performance of Shell Scientific Publications During 2017-2019 Years. Bibliometric Analysis and Mapping,2019-01-01,2019,dataset,Figshare,,,,Boris Chigarev,"**Objectives:**Mapping of bibliometric data of Shell petroleum company scientific publications during 2017-2019 years. Topic Mining and clustering. Bibliometric and citation **databases** of scientific literature: OnePetro, Scopus, Web of Science
**Used tools:**
VOSviewer - a software tool for constructing and visualizing bibliometric networks - http://www.vosviewer.com/Bibliometrix - An R-tool for comprehensive science mapping analysis - Typora - a markdown editor - https://typora.io/Notepad++ - a free source code editor - https://notepad-plus-plus.org/SmoothCSV - a powerful CSV file editor - https://smoothcsv.com/2/Queries to OnePetro:search for affiliation:""shell"" has returned 7 446 resultssearch for affiliation:(""Shell""), published between 2014 and 2019 has returned 1 633 results - allsearch for affiliation:(""Shell""), published between 2014 and 2019 has returned 1 404 results - **conference papers**search for affiliation:(""Shell""), published between 2014 and 2019 has returned 121 results - **articles**search for affiliation:(""Shell"") in **peer reviewed** articles, published between 2014 and 2019 has returned 105 resultsMain queries to Scopus:
- ( AFFILORG ( shell ) AND TITLE-ABS-KEY ( model ) ) AND PUBYEAR > 2016 613 docs- ( AFFILORG ( shell ) AND TITLE-ABS-KEY ( project* ) ) AND PUBYEAR > 2016 214 docs- ( AFFILORG ( shell ) AND TITLE-ABS-KEY ( recovery ) ) AND PUBYEAR > 2016 171 docsTests using thesaurus_terms.txt file in VOSviewer
Some starting experiments with Bibliometrix.
Using relative links in Shell.html for better viewing when bundle download",,,,,Library science; Bibliometrics; Data science; Geography; Information retrieval; Computer science,,,,,https://figshare.com/articles/Research_Performance_of_Shell_Scientific_Publications_During_2017-2019_Years_Bibliometric_Analysis_and_Mapping/8174576,http://dx.doi.org/10.6084/m9.figshare.8174576,,10.6084/m9.figshare.8174576,,,0,,0,true,cc-by,gold -035-726-207-119-758,Quantitative analysis of the publication trends in four decades of SERVQUAL research: a bibliometric approach,2024-01-02,2024,journal article,Total Quality Management & Business Excellence,14783363; 14783371,Informa UK Limited,United Kingdom,Dong-Geun Oh; B. Elango,"SERVQUAL is a critical paradigm for evaluating and maintaining service quality in a variety of service contexts and cultures. The purpose of this study is to map the SERVQUAL literature based on the Scopus and Web of Science databases using the Bibliometrix R Package. This analysis includes 2397 scientific publications on SERVQUAL and those spread between 1990 and 2022. The analysis focused the general bibliometric characteristics and trending topics: three-fourths were published between 2009 and 2022, the United States was the leading country along with some smaller countries like Iran and Malaysia, top fifteen journals published 16% of total publications, service quality and customer satisfaction are prominent topics along with SERVQUAL, country-specific studies gained momentum and researchers focused on various topics in different periods. This first study on SERVQUAL's scientific output may help researchers and decision makers find relevant topics and application areas.",35,1-2,297,319,SERVQUAL; Scopus; Service quality; Quality (philosophy); Customer satisfaction; Service (business); Marketing; Computer science; Business; Political science; MEDLINE; Philosophy; Epistemology; Law,,,,,,http://dx.doi.org/10.1080/14783363.2023.2293877,,10.1080/14783363.2023.2293877,,,0,000-566-621-938-089; 003-310-319-951-637; 004-272-316-064-751; 004-667-751-815-19X; 013-507-404-965-47X; 013-638-405-466-20X; 014-129-634-820-525; 014-229-731-858-902; 016-120-190-809-430; 016-453-674-267-274; 016-457-017-467-311; 019-740-986-808-907; 020-831-411-681-190; 023-180-872-176-018; 030-856-886-425-784; 033-322-251-876-533; 040-375-066-676-508; 042-122-854-168-181; 042-178-382-563-02X; 043-946-944-038-047; 046-582-452-889-501; 046-775-160-028-188; 047-049-336-085-523; 048-074-468-501-606; 051-365-957-989-292; 052-239-628-958-697; 052-252-716-773-162; 053-528-813-657-527; 057-433-617-492-722; 057-981-959-687-64X; 061-818-303-420-197; 062-431-368-247-700; 062-912-057-319-217; 064-262-286-609-868; 067-164-171-987-113; 067-626-596-126-240; 067-989-251-148-228; 068-318-359-720-109; 068-622-388-328-604; 071-382-642-643-801; 074-189-239-397-641; 075-169-674-958-974; 075-687-255-711-045; 080-660-675-071-196; 080-946-349-508-325; 081-070-854-033-351; 084-363-805-631-898; 086-275-275-867-31X; 088-108-398-231-703; 101-379-558-962-139; 103-417-184-433-79X; 105-724-545-515-700; 107-219-832-197-990; 111-356-723-208-174; 117-120-668-713-772; 123-654-555-937-052; 137-653-858-491-602; 139-472-427-348-855; 157-428-888-296-255; 159-357-690-478-069; 162-636-407-870-891; 171-902-178-091-581; 174-943-249-600-807; 176-010-535-784-633; 187-097-516-659-670; 191-167-630-286-148; 195-046-939-952-764,1,false,, -035-953-952-141-226,Preliminary analysis of COVID-19 academic information patterns: a call for open science in the times of closed borders.,2020-06-25,2020,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Jan Homolak; Ivan Kodvanj; Davor Virag,"The Pandemic of COVID-19, an infectious disease caused by SARS-CoV-2 motivated the scientific community to work together in order to gather, organize, process and distribute data on the novel biomedical hazard. Here, we analyzed how the scientific community responded to this challenge by quantifying distribution and availability patterns of the academic information related to COVID-19. The aim of this study was to assess the quality of the information flow and scientific collaboration, two factors we believe to be critical for finding new solutions for the ongoing pandemic. The RISmed R package, and a custom Python script were used to fetch metadata on articles indexed in PubMed and published on Rxiv preprint server. Scopus was manually searched and the metadata was exported in BibTex file. Publication rate and publication status, affiliation and author count per article, and submission-to-publication time were analysed in R. Biblioshiny application was used to create a world collaboration map. Preliminary data suggest that COVID-19 pandemic resulted in generation of a large amount of scientific data, and demonstrates potential problems regarding the information velocity, availability, and scientific collaboration in the early stages of the pandemic. More specifically, the results indicate precarious overload of the standard publication systems, significant problems with data availability and apparent deficient collaboration. In conclusion, we believe the scientific community could have used the data more efficiently in order to create proper foundations for finding new solutions for the COVID-19 pandemic. Moreover, we believe we can learn from this on the go and adopt open science principles and a more mindful approach to COVID-19-related data to accelerate the discovery of more efficient solutions. We take this opportunity to invite our colleagues to contribute to this global scientific collaboration by publishing their findings with maximal transparency.",124,3,2687,2701,Publishing; Data science; Open science; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Computer science; Preprint; Scopus; Pandemic; Metadata,Bibliometric; COVID-19; Data; Open science; Pandemic,,,,https://link.springer.com/article/10.1007/s11192-020-03587-2?error=cookies_not_supported&code=10b3693b-38cb-4858-b0bd-4c34c2666aef https://www.scilit.net/article/930e1af288c1904a7ca1c5964ca33354 https://www.ncbi.nlm.nih.gov/pubmed/32836524 https://doi.org/10.1007/s11192-020-03587-2 https://ideas.repec.org/a/spr/scient/v124y2020i3d10.1007_s11192-020-03587-2.html https://europepmc.org/article/PPR/PPR138253 https://link.springer.com/article/10.1007/s11192-020-03587-2 https://link.springer.com/content/pdf/10.1007/s11192-020-03587-2.pdf https://www.bib.irb.hr/1089706 https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics124.html#HomolakKV20,http://dx.doi.org/10.1007/s11192-020-03587-2,32836524,10.1007/s11192-020-03587-2,3014187963,PMC7315688,0,002-600-340-331-685; 008-537-158-868-338; 008-590-860-116-286; 013-507-404-965-47X; 016-131-059-057-660; 016-814-980-495-698; 022-423-141-927-508; 022-654-904-770-819; 022-664-848-011-429; 028-495-909-606-244; 031-179-884-745-873; 031-272-185-806-899; 035-953-952-141-226; 044-176-003-785-436; 067-263-492-957-015,120,true,,green -036-068-423-443-186,Pemetaan Lanskap Teori Sinyal Dalam Kewirswastaan: Perspektif Bibliometrik,2023-12-21,2023,journal article,"Journal of Economic, Bussines and Accounting (COSTING)",25975234; 25975226,IPM2KPE,,Kania Widyatami; Maya Sari,"Penelitian mengenai teori sinyal dalam konteks kewiraswastaan telah mengalami perkembangan hingga mengaburkan pemahaman mengenai bidang ini. Dengan demikian, analisis bibliometrik dilakukan untuk memecahkan masalah tersebut. Penelitian ini memanfaatkan basis data Scopus tahun 1995–2022. Data yang didapat kemudian dianalisis menggunakan paket “bibliometrix” dari R software dan aplikasi Publish or Perish. Hasil penelitian ini menyoroti tren publikasi yang ada sekaligus intellectual structure yang dapat memberi petunjuk mengenai masa lalu bidang, knowledge structure yang memberi petunjuk mengenai masa kini, dan thematic structure yang memberi petunjuk mengenai arah penelitian di masa depan. ; Kata Kunci: Teori Sinyal, Analisis Bibliometrik",7,1,2725,2732,Humanities; Political science; Philosophy,,,,,https://journal.ipm2kpe.or.id/index.php/COSTING/article/download/8511/4900 https://doi.org/10.31539/costing.v7i1.8511,http://dx.doi.org/10.31539/costing.v7i1.8511,,10.31539/costing.v7i1.8511,,,0,,0,true,,gold -036-109-072-119-146,Técnicas de extracción de colágeno: Aplicaciones y tendencias científicas,2024-08-31,2024,journal article,Manglar,18167667; 24141046,Universidad Nacional de Tumbes,,Leslie Yamilet Velez Miñano; Jennifer Camila Fernandez Baca,"The extraction of collagen from poultry by-products represents an innovative solution for waste management and the production of high added value bioproducts. This study reviews collagen extraction methods, with emphasis on hydrolysis, and their applications in the food, biomedical, and cosmetic industries. A bibliometric analysis was performed using the Scopus database and the VosViewer and Bibliometrix tools to identify research trends and international collaboration. The objective was to provide an overview of the current state of research on collagen extraction from animal tissues and its applications. The results show a growing global interest in this field, with China and Brazil leading in number of publications. An evolution is observed in extraction methods, from traditional approaches to more efficient and sustainable techniques. The conclusions highlight the potential of collagen extracted from by-products to promote sustainability and innovation in various industries, as well as the importance of international collaboration and interdisciplinary research to drive significant advances in this field.",21,3,391,399,Physics; Humanities; Art,,,,,,http://dx.doi.org/10.57188/manglar.2024.043,,10.57188/manglar.2024.043,,,0,,0,true,cc-by,gold -036-136-746-096-854,Engineering education for sustainable development: Bibliometric analysis,2023-01-01,2023,journal article,Journal of Engineering Education Transformations,23492473; 23941707,Rajarambapu Institute of Technology,,Harith Sai Saraf; S Pavan Kumar,"Bibliometrics is a tool to evaluate and comprehend work. Its usage is steadily spreading to various disciplines. The main aim of this research paper is twofold. Firstly, to use bibliometrix as an R package tool to provide bibliometric information on 1,995 publications considered from the Scopus database. Secondly, to serve as a source for finding answers to new scientific questions through further research on engineering education for sustainable development. It is not hard to understand that higher education, especially engineering education, has a more significant role in realizing the Sustainable Development Goals (SDG) 2030. A review of research papers on engineering education and sustainable development published between 2010 and 2023 was conducted. The bibliometrix analysis identified the current level of research on Engineering Education for Sustainable Development (EESD). Through the results of this study, we have broadened our understanding of who, which, and what aspects of EESD, as well as possible research areas in EESD to explore. This study presents implications and recommendations for the people at the helm of authority in engineering education institutions and policymakers. They can play an instrumental role in developing a society with a sustainable future. Keywords: Bibliometrics, Bibliometrix, Engineering Education, Sustainable development, R package tool, Sustainable development goals",36,S2,575,581,Scopus; Sustainable development; Bibliometrics; Work (physics); Engineering ethics; Engineering education; Higher education; Education for sustainable development; Engineering management; Knowledge management; Management science; Computer science; Engineering; Political science; Library science; Mechanical engineering; MEDLINE; Law,,,,,,http://dx.doi.org/10.16920/jeet/2023/v36is2/23088,,10.16920/jeet/2023/v36is2/23088,,,0,,2,true,,gold -036-136-780-386-871,A Bibliometric Analysis of Artificial Intelligence and Human Resource Management Studies,2023-12-29,2023,book chapter,Advances in Human Resources Management and Organizational Development,23273372; 23273380,IGI Global,,Azizan Bin Morshidi; Nurhizam Safie Mohd Satar; Azueryn Annatassia Dania Aqeela Azizan; Rizal Zamani Idris; Rafiq Idris; Mohammad Shaukhi Md Radzi; Sitinurbayu Mohd Yusoff; Fauzie Sarjono,"The pervasiveness of artificial intelligence (AI) within contemporary organisations is an undeniable phenomenon. The primary objective of this chapter is to undertake a meticulous bibliometric analysis of the scholarly literature that investigates the interconnected exploration of the utilisation and ramifications of artificial intelligence (AI) within the realm of human resource management (HRM). The researchers consulted the valued scientific database Scopus, which proved to be a fount of knowledge. Ninety-one documents were initially retrieved and meticulously chosen for the analysis. The data underwent processing through the esteemed Bibliometrix software and the sophisticated Biblioshiny application tool. The results evince that the application of artificial intelligence (AI) to human resource management (HRM) constitutes an emerging domain of inquiry, characterised by a continuous and unwavering expansion and a promising trajectory for the future. Finally, the discourse examined the comparative themes that emerged before and after the advent of the COVID-19 pandemic.",,,85,117,Realm; Scopus; Resource (disambiguation); Knowledge management; Human resource management; Computer science; Data science; Management science; Artificial intelligence; Engineering; Political science; History; Archaeology; Computer network; MEDLINE; Law,,,,,,http://dx.doi.org/10.4018/979-8-3693-0039-8.ch006,,10.4018/979-8-3693-0039-8.ch006,,,0,001-045-782-457-414; 009-015-682-399-02X; 012-170-569-200-662; 012-647-480-253-755; 013-507-404-965-47X; 015-453-047-031-055; 019-491-687-008-913; 020-426-411-955-199; 021-323-111-834-306; 039-728-321-142-083; 041-023-949-864-26X; 042-957-639-612-409; 045-809-500-648-890; 046-759-686-839-997; 047-381-240-144-095; 047-455-760-046-869; 048-327-009-812-31X; 051-205-660-101-464; 058-054-088-267-883; 058-419-583-918-97X; 060-754-447-776-807; 060-903-005-827-511; 065-324-604-179-881; 066-028-428-192-648; 072-029-923-588-916; 077-027-719-925-914; 080-643-194-734-089; 083-106-354-746-202; 083-624-254-056-466; 088-363-797-675-334; 088-530-107-249-860; 090-693-745-265-230; 091-705-489-446-869; 098-682-223-508-79X; 099-780-094-104-283; 100-679-169-763-863; 101-687-595-137-554; 107-033-347-406-909; 108-393-377-527-600; 113-128-934-174-427; 117-055-341-652-447; 119-628-892-577-373; 124-460-151-627-198; 124-745-398-943-714; 127-356-760-504-467; 129-899-122-917-359; 134-181-543-786-906; 136-681-200-010-077; 145-059-240-052-534; 149-830-000-129-098; 152-714-342-662-220; 157-389-702-246-171; 176-646-534-270-087; 178-046-826-912-364; 183-039-543-585-215; 186-957-158-403-691; 189-837-124-179-153; 190-393-137-680-001,4,false,, -036-405-596-112-216,The significance of goat milk in enhancing nutrition security: a scientiometric evaluation of research studies from 1966 to 2020,2023-11-09,2023,journal article,Agriculture & Food Security,20487010,Springer Science and Business Media LLC,United Kingdom,Emrobowansan Monday Idamokoro,"Abstract; Background; The present study aimed to reveal scientific findings on goat milk as an instrument to combat food and nutrition insecurity, while considering the recurrent challenge posed by food dearth and high rise of hunger among susceptible people of numerous nations.; ; Results; A sum of 9206 research outputs were extracted in a BibTeX design for evaluation by means of bibliometric package in R studio software. The generated result included, but not restricted to authors, citations, affiliations, journals and key words. Published research findings on goat milk as related to nutrition security retrieved from web of science (WOS) and Scopus data bases were used with an increase in scientific findings of an annual growth of 14.42% during the period of study. From the result of the study, Spain was rated in first position with a total of publications (n = 953), and a massive global scientific influence with the highest article citations (n = 17,035). The most commonly referred authors’ keywords in this research field were goat/s (n = 1605), milk (n = 920), dairy goat/s (n = 372), fatty acid/s (n = 307), cheese (n = 251), milk production (n = 220), milk consumption (n = 173), which all together gave a hint on associated research studies on goat milk and nutrition security.; ; Conclusions; The current study presented a global picture that covers the pool of scientific knowledge on goat milk research and its relevance in nutrition security, while giving a direction for more studies in this research area. It is of utmost importance to stress that the present findings only addressed prime areas of goat milk production as linked to nutrition security research, therefore, it is proposed that novel empirical study and potential research outcomes would give new understanding and insight on goat milk utilization as an avenue to tackle nutrition security issues as new findings emerges.; ",12,1,,,Scopus; Web of science; Relevance (law); Milk production; Food security; Consumption (sociology); Food science; Political science; Social science; Geography; Biology; Animal science; Sociology; MEDLINE; Agriculture; Archaeology; Law,,,,,https://agricultureandfoodsecurity.biomedcentral.com/counter/pdf/10.1186/s40066-023-00441-5 https://doi.org/10.1186/s40066-023-00441-5,http://dx.doi.org/10.1186/s40066-023-00441-5,,10.1186/s40066-023-00441-5,,,0,002-786-264-150-417; 002-983-521-978-761; 005-434-636-280-811; 006-789-184-479-502; 008-471-561-228-243; 008-760-387-467-169; 009-839-334-676-168; 010-164-632-900-669; 010-475-167-301-561; 011-300-800-146-555; 011-391-939-662-665; 013-003-939-631-952; 013-507-404-965-47X; 014-812-893-775-913; 018-018-785-295-573; 022-828-875-803-286; 033-777-638-324-611; 035-330-847-069-591; 037-674-369-173-854; 039-821-367-454-492; 043-627-211-692-30X; 044-481-666-575-588; 045-404-097-982-753; 046-756-470-609-742; 046-790-171-133-501; 050-552-987-586-715; 053-104-475-700-596; 054-439-051-844-343; 056-441-439-197-934; 059-642-270-769-342; 063-526-154-713-217; 064-418-660-662-596; 064-880-308-426-113; 067-456-603-759-590; 068-439-084-657-120; 073-008-010-322-076; 075-562-456-673-496; 076-792-449-044-149; 077-553-574-890-852; 087-079-901-483-363; 087-172-326-777-336; 088-908-268-737-277; 108-665-599-652-032; 111-663-336-945-967; 112-518-121-474-665; 121-064-499-844-149; 124-187-743-925-055; 127-048-745-950-798; 127-200-308-977-777; 127-645-778-235-147; 134-928-742-404-897; 136-211-937-581-097; 142-608-256-821-705; 147-166-442-159-619; 150-467-309-378-385; 151-322-901-650-404; 155-753-271-453-114; 166-424-150-434-410; 170-284-136-077-739,6,true,"CC BY, CC0",gold -036-474-096-703-342,Exploring the status of artificial intelligence for healthcare research in Africa: a bibliometric and thematic analysis,2023-10-23,2023,journal article,AI and Ethics,27305953; 27305961,Springer Science and Business Media LLC,,Tabu S. Kondo; Salim A. Diwani; Ally S. Nyamawe; Mohamed M. Mjahidi,"Abstract; This paper explores the status of Artificial Intelligence (AI) for healthcare research in Africa. The aim was to use bibliometric and thematic analysis methods to determine the publication counts, leading authors, top journals and publishers, most active institutions and countries, most cited institutions, funding bodies, top subject areas, co-occurrence of keywords and co-authorship. Bibliographic data were collected on April 9 2022, through the Lens database, based on the critical areas of authorship studies, such as authorship pattern, number of authors, etc. The findings showed that several channels were used to disseminate the publications, including articles, conference papers, reviews, and others. Publications on computer science topped the list of documented subject categories. The Annals of Tropical Medicine and Public Health is the top journal, where articles on AI have been published. One of the top nations that published AI research was the United Kingdom. With 143 publications, Harvard University was the higher education institution that produced the most in terms of affiliation. It was discovered that the Medical Research Council was one of the funding organizations that supported research, resulting in the publication of articles in AI. By summarizing the current research themes and trends, this work serves as a valuable resource for researchers, practitioners, and funding organizations interested in Artificial intelligence for healthcare research in Africa.",5,1,117,138,Subject (documents); Health care; Library science; Thematic analysis; Bibliometrics; Political science; Public relations; Medical education; Social science; Sociology; Medicine; Computer science; Qualitative research; Law,,,,International Development Research Centre,https://link.springer.com/content/pdf/10.1007/s43681-023-00359-5.pdf https://doi.org/10.1007/s43681-023-00359-5,http://dx.doi.org/10.1007/s43681-023-00359-5,,10.1007/s43681-023-00359-5,,,0,000-096-142-707-44X; 001-941-561-806-831; 013-507-404-965-47X; 015-441-632-855-153; 015-626-569-953-72X; 015-813-601-387-97X; 016-941-263-466-562; 017-750-600-412-958; 018-393-224-068-367; 019-579-614-254-335; 019-932-800-915-381; 020-538-061-498-827; 021-193-931-552-31X; 022-047-566-061-758; 023-478-802-370-116; 025-214-649-678-627; 026-120-402-124-904; 040-903-983-379-152; 042-068-946-333-004; 043-930-196-662-920; 047-232-932-356-567; 052-873-153-319-311; 053-907-820-992-569; 055-558-344-452-712; 056-367-777-950-439; 060-649-162-099-019; 060-734-384-362-229; 062-141-256-200-574; 067-600-353-893-909; 068-064-417-946-548; 074-206-719-066-990; 075-849-007-856-623; 078-802-500-364-017; 080-283-453-376-946; 082-261-822-310-666; 083-655-573-187-297; 083-990-878-792-576; 087-997-901-057-244; 095-607-152-696-922; 105-936-662-012-269; 108-358-496-436-118; 114-961-267-046-646; 121-191-664-124-631; 123-978-309-092-892; 124-210-955-184-554; 134-571-095-333-121; 137-033-450-234-875; 149-426-433-408-67X; 151-107-386-220-343; 151-662-245-739-62X; 156-997-435-234-418; 161-438-799-040-059; 175-193-184-924-443,2,true,cc-by,hybrid -036-690-207-525-670,ESTUDO BIBLIOMÉTRICO SOBRE MÉTODOS MULTICRITÉRIOS DE APOIO À DECISÃO (MCDA) APLICADOS EM ESTUDOS PARA ORDENAÇÃO DE ATIVOS NO SETOR DE COMBUSTÍVEIS: UMA APLICAÇÃO UTILIZANDO A PLATAFORMA BIBLIOMETRIX,,2024,conference proceedings article,Simpósio de Engenharia de Produção - SIMEP,23189258,Even3,,Guilherme Portilho Joaquim; Carlos Francisco Simões Gomes; Prof. Dr. Marcos Santos (IME),,1,,,,Physics,,,,,,http://dx.doi.org/10.29327/12simep.793870,,10.29327/12simep.793870,,,0,,0,false,, -036-741-684-386-623,Scientometric analysis of financial technology and innovation under digital transformation,2024-05-08,2024,book chapter,"Advances in Economics, Business and Management Research",27317854; 23525428,Atlantis Press International BV,,Yu-Tsung Pan; Shiyao Zhang; Chung-Lien Pan,"With the rapid development of science and technology and the advancement of digital transformation, financial technology and innovation have received widespread attention around the world.This article conducted a systematic search on the Web of Science (WoS) database and used scientometric analysis methods to select 116 research papers retrieved from 1900 to 2023.And use Vosviewer and Bibliometrix software to visualize the paper data.The results show that this research topic has shown rapid growth from 2017 to 2023, and four groups of keywords, including digital transformation, digital economy, financial technology, and e-commerce, have contributed the most to the research.Among the subject countries, China, the United States, and the United Kingdom are the most important in this field.",,,97,103,Digital transformation; Transformation (genetics); Business; Computer science; World Wide Web; Biochemistry; Chemistry; Gene,,,,,https://www.atlantis-press.com/article/125999568.pdf https://doi.org/10.2991/978-94-6463-408-2_12,http://dx.doi.org/10.2991/978-94-6463-408-2_12,,10.2991/978-94-6463-408-2_12,,,0,,0,true,cc-by-nc,hybrid -037-171-850-013-561,Internet of things based innovative solutions and emerging research clusters in circular economy,2023-10-12,2023,journal article,Operations Management Research,19369735; 19369743,Springer Science and Business Media LLC,United States,Sunil Jauhar; Saurabh Pratap; null Lakshay; Sanjoy Paul; Angappa Gunasekaran,,16,4,1968,1988,Circular economy; Internet of Things; Digitization; Traceability; Bibliometrics; Field (mathematics); Digital economy; Supply chain; The Internet; Computer science; Business; Data science; Marketing; World Wide Web; Telecommunications; Ecology; Mathematics; Software engineering; Pure mathematics; Biology,,,,,,http://dx.doi.org/10.1007/s12063-023-00421-9,,10.1007/s12063-023-00421-9,,,0,000-027-768-030-400; 000-701-983-500-585; 001-821-162-595-153; 004-697-958-177-428; 006-599-738-913-706; 007-554-722-524-922; 007-671-298-875-960; 009-174-694-656-001; 011-288-108-358-499; 012-812-386-476-924; 013-507-404-965-47X; 013-525-119-231-396; 013-969-742-356-497; 014-114-452-853-877; 015-211-004-330-221; 020-581-472-422-02X; 021-095-778-383-177; 025-413-766-063-623; 026-591-128-884-388; 027-186-937-456-874; 027-350-720-314-009; 028-069-456-289-669; 030-601-865-733-53X; 030-686-554-327-070; 034-204-621-111-626; 038-740-855-920-965; 038-946-406-643-062; 041-255-765-888-788; 042-228-490-689-212; 042-394-228-997-686; 045-716-736-824-368; 046-281-706-710-892; 048-020-109-122-133; 048-872-880-871-621; 057-029-226-391-989; 057-401-297-630-527; 058-081-424-637-980; 058-875-393-177-719; 061-199-367-867-916; 064-618-058-333-462; 064-749-779-222-180; 065-138-143-697-782; 065-971-302-216-166; 066-157-822-409-471; 067-975-723-728-662; 069-725-014-389-70X; 070-265-608-752-431; 072-102-632-250-972; 076-265-183-084-543; 076-303-271-715-610; 076-690-767-175-163; 077-128-451-912-604; 077-233-209-239-970; 079-130-332-681-124; 083-227-817-804-415; 085-450-187-024-856; 086-453-406-250-096; 092-450-726-509-283; 093-657-030-416-171; 095-064-973-269-938; 096-336-736-778-467; 097-714-362-890-826; 099-478-698-777-879; 100-345-591-574-70X; 101-752-490-869-458; 102-189-739-165-015; 103-370-509-856-681; 104-417-030-773-747; 105-032-479-005-413; 107-443-019-772-100; 107-831-670-078-761; 112-063-913-978-660; 115-111-331-159-828; 117-798-303-530-200; 118-108-053-190-949; 125-114-573-179-078; 126-675-892-269-309; 127-329-814-948-474; 128-336-465-791-65X; 130-819-541-291-621; 132-381-931-518-907; 133-255-951-610-048; 134-975-916-359-072; 143-498-557-538-825; 144-801-246-492-626; 145-776-106-149-505; 149-269-099-266-71X; 149-322-612-082-39X; 154-973-286-971-035; 180-571-441-900-984; 190-316-915-043-879; 195-553-356-699-468,17,false,, -037-426-339-293-65X,Worldwide trends in prediabetes from 1985 to 2022: A bibliometric analysis using bibliometrix R-tool.,2023-02-13,2023,journal article,Frontiers in public health,22962565,Frontiers Media SA,Switzerland,JingYi Zhao; Min Li,"Prediabetes is a widespread condition that represents the state between normal serum glucose and diabetes. Older individuals and individuals with obesity experience a higher rate of prediabetes. Prediabetes is not only a risk factor for type 2 diabetes mellitus (t2dm) but is also closely related to microvascular and macrovascular complications. Despite its importance, a bibliometric analysis of prediabetes is missing. The purpose of this study is to provide a comprehensive and visually appealing overview of prediabetes research.; First, the Web of Science (WOS) database was searched to collect all articles related to prediabetes that were published from 1985 to 2022. Second, R language was used to analyze the year of publication, author, country/region, institution, keywords, and citations. Finally, network analysis was conducted using the R package bibliometrix to evaluate the hotspots and development trends of prediabetes.; A total of 9,714 research articles published from 1985 to 2022 were retrieved from WOS. The number of articles showed sustained growth. Rathmann W was the most prolific author with 71 articles. Diabetes Care was the journal that published the highest number of articles on prediabetes (234 articles), and Harvard University (290 articles) was the most active institution in this field. The United States contributed the most articles (2,962 articles), followed by China (893 articles). The top five clusters of the keyword co-appearance network were ""prediabetes"", ""diabetes mellitus"", ""glucose"", ""insulin exercise"", and ""oxidative stress"". The top three clusters of the reference co-citation network were ""Knowler. WC 2002"", ""Tabak AG 2012"", and ""Matthews DR1985"".; The combined use of WOS and the R package bibliometrix enabled a robust bibliometric analysis of prediabetes papers, including evaluation of emerging trends, hotspots, and collaboration. This study also allowed us to validate our methodology, which can be used to better understand the field of prediabetes and promote international collaboration.; Copyright © 2023 Zhao and Li.",11,,1072521,,Prediabetes; Medicine; Diabetes mellitus; Gerontology; Citation; Obesity; Web of science; MEDLINE; Type 2 diabetes; Demography; Family medicine; Library science; Internal medicine; Computer science; Endocrinology; Political science; Meta-analysis; Sociology; Law,R language; bibliometrics; bibliometrix; diabetes; prediabetes,"Humans; Diabetes Mellitus, Type 2; Prediabetic State; Bibliometrics; China; Databases, Factual",,Natural Science Foundation of Beijing Municipality,https://www.frontiersin.org/articles/10.3389/fpubh.2023.1072521/pdf https://doi.org/10.3389/fpubh.2023.1072521,http://dx.doi.org/10.3389/fpubh.2023.1072521,36908460,10.3389/fpubh.2023.1072521,,PMC9993478,0,000-216-702-761-174; 000-349-525-383-844; 000-487-942-111-888; 002-436-059-214-91X; 003-044-899-593-725; 003-774-488-767-844; 006-155-419-059-824; 006-428-619-659-374; 006-441-158-797-753; 007-660-475-984-655; 007-770-012-991-282; 010-065-762-504-134; 010-232-742-451-931; 010-833-965-100-286; 013-239-858-650-853; 013-306-637-472-35X; 013-507-404-965-47X; 013-524-854-219-241; 014-637-489-491-286; 017-294-131-147-867; 018-350-445-661-228; 019-891-969-858-089; 021-826-666-890-509; 027-137-180-479-554; 027-725-202-314-12X; 033-250-761-688-014; 034-388-455-516-925; 034-455-232-089-29X; 038-499-232-992-833; 044-110-395-610-552; 044-501-968-205-211; 046-499-647-998-970; 051-363-731-225-039; 051-647-739-244-271; 057-347-805-952-609; 065-200-015-445-470; 065-284-154-322-498; 067-763-395-726-179; 068-870-989-227-529; 070-245-566-084-229; 078-072-721-119-937; 086-072-064-921-945; 088-616-165-370-172; 091-753-517-092-831; 105-048-664-663-772; 108-049-868-820-155; 110-131-013-132-044; 127-336-377-914-270; 164-024-307-525-551; 175-947-468-427-025,24,true,cc-by,gold -037-575-137-909-363,Advancements in Bankruptcy Prediction Models and Bibliometric Analysis,2024-06-26,2024,journal article,European Conference on Research Methodology for Business and Management Studies,20490976; 20490968,Academic Conferences International Ltd,,Amanda Zetzsche de Abreu Gomes; Cristina Lopes; Rui Bertuzi da Silva,"Since the economic downturn of the 1930s, there has been a growing interest in predicting company bankruptcies. Though not a new topic, the prospect of business bankruptcy has gained increasing relevance due to globalisation. This study explores various methodologies employed in predicting bankruptcy. Preventing bankruptcies also bolsters economic stability by averting the adverse effects of insolvency on the community. Companies with a solid and flexible economic foundation are more likely to succeed. This article reviews existing literature, discusses prevalent predictive models, and presents a statistical analysis of bibliometric data associated with bankruptcy prediction. This work aims to answer the research question of identifying the trends over time in the econometric models used to predict bankruptcy. This article may be useful for finance and business students in providing an overview of the subject and for business managers to identify the key determinants of financial distress. Exploring the R package, Bibliometrix® demonstrates its efficacy as a powerful tool for science mapping.",23,1,82,91,Bankruptcy; Bankruptcy prediction; Bibliometrics; Zhàng; Computer science; Econometrics; Data science; Actuarial science; Business; Economics; Geography; Data mining; China; Finance; Archaeology,,,,,,http://dx.doi.org/10.34190/ecrm.23.1.2428,,10.34190/ecrm.23.1.2428,,,0,,0,false,, -037-640-460-121-822,Bibliometric analysis of scientific production in occupational health nursing.,2024-02-16,2024,journal article,Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT,16794435; 24470147,EDITORA SCIENTIFIC,Brazil,Miguel Valencia-Contrera; Flérida Rivera-Rojas,"Occupational health nursing, formerly known as industrial nursing, which in turn has its foundations in public health, develops preventive, assistance, legal, and expert activities, as well as management, teaching, and research, the last of which updates knowledge and provides answers to questions arising from clinical experience. The aim of this article was to analyze the scientific production about occupational health nursing in Scopus and Web of Science databases. This is a retrospective, descriptive, bibliometric study on the scientific production about occupational health nursing in which scientific evidence was analyzed and characterized using Bibliometrix software. An unequal scientific production was evidenced, with a higher proportion of publications in countries such as the United States, South Korea, Brazil, and Spain; furthermore, there has been a sustained growth in the number of publications, whose topics of greatest interest were associated with health, risks, exposures, and care.",21,4,e20231135,7,Production (economics); Nursing; Medicine; Environmental health; Economics; Macroeconomics,bibliometrics; nursing; nursing research; occupational health; occupational health nursing,,,,https://rbmt.org.br/export-pdf/1958/e20231135.pdf https://doi.org/10.47626/1679-4435-2023-1135,http://dx.doi.org/10.47626/1679-4435-2023-1135,39132280,10.47626/1679-4435-2023-1135,,PMC11316541,0,033-445-927-061-124; 048-668-871-325-751; 062-890-036-138-631; 069-799-103-293-242,0,true,cc-by,gold -037-809-955-172-796,Blockchain Consensus Mechanisms: A Bibliometric Analysis (2014–2024) Using VOSviewer and R Bibliometrix,2024-10-16,2024,journal article,Information,20782489,MDPI AG,Switzerland,Joongho Ahn; Eojin Yi; Moonsoo Kim,"Blockchain consensus mechanisms play a critical role in ensuring the security, decentralization, and integrity of distributed networks. As blockchain technology expands beyond cryptocurrencies into broader applications such as supply chain management and healthcare, the importance of efficient and scalable consensus algorithms has grown significantly. This study provides a comprehensive bibliometric analysis of blockchain and consensus mechanism research from 2014 to 2024, using tools such as VOSviewer and R’s Bibliometrix package. The analysis traces the evolution from foundational mechanisms like Proof of ork (PoW) to more advanced models such as Proof of Stake (PoS) and Byzantine Fault Tolerance (BFT), with particular emphasis on Ethereum’s “The Merge” in 2022, which marked the historic shift from PoW to PoS. Key findings highlight emerging themes, including scalability, security, and the integration of blockchain with state-of-the-art technologies like artificial intelligence (AI), the Internet of Things (IoT), and energy trading. The study also identifies influential authors, institutions, and countries, emphasizing the collaborative and interdisciplinary nature of blockchain research. Through thematic analysis, this review uncovers the challenges and opportunities in decentralized systems, underscoring the need for continued innovation in consensus mechanisms to address efficiency, sustainability, scalability, and privacy concerns. These insights offer a valuable foundation for future research aimed at advancing blockchain technology across various industries.",15,10,644,644,Blockchain; Computer science; Data science; Computer security,,,,,,http://dx.doi.org/10.3390/info15100644,,10.3390/info15100644,,,0,001-149-895-789-825; 002-052-422-936-00X; 005-353-430-670-414; 006-063-506-340-755; 007-987-721-215-304; 008-781-292-444-67X; 009-173-345-925-096; 009-567-482-116-772; 011-301-822-302-672; 011-963-782-774-175; 013-507-404-965-47X; 013-524-854-219-241; 016-936-798-222-306; 017-363-020-138-219; 017-960-701-844-51X; 022-717-829-704-63X; 025-211-321-952-916; 027-436-017-320-56X; 028-042-211-603-015; 028-524-009-565-811; 029-153-333-542-677; 032-169-069-596-979; 032-966-446-271-531; 035-187-339-680-643; 036-036-811-187-878; 038-845-029-996-213; 042-057-360-478-480; 044-070-690-928-973; 045-961-475-607-195; 047-663-692-540-393; 051-647-739-244-271; 053-786-467-071-25X; 054-159-894-171-769; 054-219-449-433-611; 054-792-991-892-414; 055-272-736-924-578; 056-216-240-850-368; 058-883-279-154-919; 066-775-281-325-512; 070-579-764-594-430; 070-786-223-957-376; 071-725-568-539-708; 071-791-747-721-674; 073-775-823-470-313; 074-219-293-723-692; 083-860-858-902-680; 083-888-956-568-609; 084-786-111-684-500; 091-919-446-801-473; 092-450-726-509-283; 095-793-519-782-23X; 095-827-156-834-59X; 100-354-388-738-259; 101-758-216-347-128; 110-217-691-116-745; 120-447-427-142-860; 129-347-269-939-709; 130-129-803-339-202; 133-403-562-460-084; 134-985-477-712-653; 143-894-897-226-398; 147-265-772-955-830; 152-842-277-605-807; 152-957-152-806-584; 153-993-151-696-648; 158-671-100-912-46X; 165-306-221-368-542; 167-899-284-968-245; 169-476-984-370-816; 169-695-779-576-989; 176-357-413-418-603; 182-681-332-428-844; 182-728-491-181-012; 185-824-085-505-359; 186-577-326-411-937; 192-743-385-236-655; 199-105-079-586-006,6,true,cc-by,gold -037-885-712-017-796,Biodegradation of Marine Pollutants by Microorganisms: A Bibliometric Analysis,2022-12-25,2022,journal article,Research in Biotechnology and Environmental Science,29807743,Rovedar,,Hussein Alwan; Ali Resen; Abdolhadi Bashar; Aqeel Abdulabbas; Mehdi Hassanshahian,"The oceans, as a large area of the planet, are of great importance to the biological status of organisms. They are contaminated with different compounds that are dangerous to health conditions. Biodegradation is one way to reduce pollution. Therefore the current review aimed to this bibliometric analysis. Data were collected from published articles in Scopus and Clarivate Analytics Web of Science databases between 1985 and April 2021, and then Scopus documents were examined using VOS viewer and Bibliometrix-package due to their larger number. Analysis was performed for the number of publications per year, document types, sources, keywords, authors, organizations, and countries. The results showed a growing trend in publishing documents from 2010 to 2022. The two keywords biodegradation and bioremediation grew more.",1,2,43,53,Scopus; Web of science; Biodegradation; Bioremediation; Analytics; Environmental science; Computer science; Data science; Contamination; Biology; Ecology; MEDLINE; Biochemistry,,,,,https://rbes.rovedar.com/index.php/RBES/article/download/8/10 https://doi.org/10.58803/rbes.v1i2.8 https://zenodo.org/records/8380840/files/2.PN2.pdf https://zenodo.org/record/8380840,http://dx.doi.org/10.58803/rbes.v1i2.8,,10.58803/rbes.v1i2.8,,,0,,5,true,cc-by,hybrid -038-044-119-229-181,Bibliometrix Analysis: Trade Process Information Systems in Tangerang Modern Land Market,2023-04-10,2023,journal article,eCo-Buss,26224305; 26224291,Komunitas Dosen Indonesia,,Novita Trisetyo; Riki Riki,"Developing an information system that can facilitate the trading process at Pasar Modernland Tangerang. Pasar Modernland Tangerang is a modern market that has various types of traders and products offered to consumers. However, the trading process in this market still faces a number of obstacles, such as a lack of efficiency, lack of transparency, and difficulties in managing trade data. Therefore, this study aims to design and implement an information system that can help improve the trading process at Pasar Modernland Tangerang. Study This aim For develop system information that facilitates the trading process at Pasar Modernland Tangerang. Pasar Modernland Tangerang is a modern market that has various type merchants and products offered to consumer. The research method used in the given text is a systematic literature review. The text describes the process of conducting a bibliometric analysis to identify relevant publications for research. This study used a combination of keywords, filtering by time, type of publication, open access, language, and removal of duplicates to screen studies that fit the research objectives. This helps researchers narrow the range of studies to be synthesized and analyzed(Rojas-Sánchez et al., 2023). The information system designed and implemented in the study aimed to increase efficiency, strengthen transparency, and ease trading data management. The system covered several important features, such as trader registration and profile management, online ordering and payment, inventory management, and trading data reports and analysis. The system was expected to help increase the quality of service for consumers, make it easy for merchants to manage their business, and increase the potential growth of the economy in the market area",5,3,1158,1178,Transparency (behavior); Business; Process (computing); Payment; Computer science; Finance; Computer security; Operating system,,,,,,http://dx.doi.org/10.32877/eb.v5i3.824,,10.32877/eb.v5i3.824,,,0,,0,false,, -038-158-444-208-70X,Research Guides: Introduction to R Studio: Bibliometrix data file,2018-11-07,2018,libguide,,,,,Jay Forrest,,,,,,Data file; Computer science; Studio; Multimedia,,,,,https://libguides.gatech.edu/RStudio/Bibliometrix,https://libguides.gatech.edu/RStudio/Bibliometrix,,,3084944048,,0,,0,false,, -038-790-670-305-072,Interactive Websites in Physics Education: A Bibliometric Analysis and Trends Review,2024-12-26,2024,journal article,Jurnal Ilmiah Pendidikan Fisika,25499963; 25499955,"Center for Journal Management and Publication, Lambung Mangkurat University",,Kissi Marwanti; Firmanul Catur Wibowo; Hadi Nasbey,"This study examines the trend and contribution of interactive websites in physics education through bibliometric analysis. Using R Bibliometrix, 38 articles from 1999 to 2024 were analyzed in annual scientific production, country scientific production, most cited countries, most cited documents globally, and word clouds. The types of documents obtained from the Scopus database in the form of articles, book chapters, conference papers, and conference reviews. The findings of the analysis show that the key trends include students, websites, e-learning, education, and teaching. While gaps remain in interactive learning tools, learning experiences, learning management systems, learning processes, and differentiation. This study could serve as a global guide for researchers and educators creating interactive physics learning websites.",8,3,496,496,Data science; Library science; Computer science,,,,,,http://dx.doi.org/10.20527/jipf.v8i3.14190,,10.20527/jipf.v8i3.14190,,,0,,0,true,cc-by-sa,hybrid -039-622-921-589-756,A bibliometric overview of cultural intelligence (CQ) research,2023-03-30,2023,book chapter,Handbook of Cultural Intelligence Research,,Edward Elgar Publishing,,Andrea Caputo; Mariya Kargina,"This chapter investigates, maps, and systematizes the knowledge produced around cultural intelligence in social sciences, particularly management studies, over the last two decades. A bibliometric analysis of 513 documents retrieved from the Web of Science Core Collection database has been made via the bibliometrix package in R, covering a range of studies from 2002 until 2020. The analyses present results concerning the performance of CQ research published in scientific journals, the geography of CQ research, and the identification of the main articles and topics.",,,413,430,Identification (biology); Web of science; Data science; Library science; Geography; Computer science; Political science; MEDLINE; Biology; Ecology; Law,,,,,,http://dx.doi.org/10.4337/9781800887169.00038,,10.4337/9781800887169.00038,,,0,,1,false,, -039-724-459-066-089,Determinants of artificial intelligence adoption: research themes and future directions,2024-08-23,2024,journal article,Information Technology and Management,1385951x; 15737667,Springer Science and Business Media LLC,Netherlands,Ahmad A. Khanfar; Reza Kiani Mavi; Mohammad Iranmanesh; Denise Gengatharen,"AbstractThe adoption of artificial intelligence (AI) systems is on the rise owing to their many benefits. This study conducted a bibliometric analysis to identify (1) how the literature on AI adoption has evolved over the past few years, (2) key themes associated with AI adoption in the literature, and (3) the gaps in the literature. To achieve these objectives, we utilised the Biblioshiny of R-package bibliometric analysis tool to analyse the AI adoption literature. A total of 91 articles were reviewed and analysed in this study. Four major themes were identified: AI, machine learning, the unified theory of acceptance and use of technology (UTAUT) model and the technology acceptance model (TAM). Using a content analysis of the identified themes, the study gained additional insight into the studies on AI adoption. Previous studies have been limited to specific industries and systems, and adoption theories like the UTAUT and TAM have also been utilised to a limited extent. Directions for future studies were provided.",,,,,Psychology; Data science; Management science; Computer science; Engineering,,,,Edith Cowan University,,http://dx.doi.org/10.1007/s10799-024-00435-0,,10.1007/s10799-024-00435-0,,,0,000-599-749-388-312; 003-252-903-980-303; 003-730-983-078-048; 011-084-542-106-943; 011-232-616-391-68X; 011-647-337-947-571; 011-746-251-969-407; 012-380-263-483-968; 013-507-404-965-47X; 013-524-854-219-241; 013-895-873-651-120; 014-293-767-032-770; 015-583-058-931-02X; 016-347-525-888-529; 017-195-475-460-140; 019-420-104-098-390; 020-422-805-048-200; 021-916-640-763-13X; 027-176-441-427-157; 027-777-053-351-238; 027-972-359-096-173; 033-411-682-581-029; 033-639-517-000-164; 034-663-388-410-701; 035-754-571-664-486; 036-654-622-595-950; 036-797-275-496-832; 038-382-202-143-225; 038-420-930-140-22X; 040-787-369-536-626; 043-608-626-221-602; 046-221-256-075-961; 046-992-864-415-70X; 049-298-180-478-565; 051-472-143-393-282; 051-647-739-244-271; 053-387-315-531-079; 054-124-784-781-881; 054-994-955-531-158; 055-486-693-974-72X; 055-526-856-766-92X; 061-532-955-818-105; 070-390-514-493-275; 071-833-629-169-199; 072-619-743-125-084; 079-436-597-029-678; 080-406-450-644-623; 080-842-342-189-88X; 081-763-210-910-306; 082-456-814-757-003; 082-942-564-795-595; 084-518-919-853-724; 091-374-622-503-09X; 098-906-028-922-784; 100-400-989-676-705; 110-174-650-707-998; 110-575-923-602-903; 116-950-664-040-634; 118-004-476-168-229; 120-740-874-159-798; 128-266-888-487-309; 131-183-591-334-12X; 134-692-988-441-892; 136-311-555-754-755; 136-515-074-193-541; 137-675-799-864-823; 140-115-143-704-715; 141-681-918-254-506; 141-749-059-221-703; 144-322-272-133-266; 147-047-917-758-50X; 148-059-872-406-061; 149-489-334-550-425; 154-958-212-177-335; 159-635-569-703-153; 159-825-055-145-526; 168-783-147-220-726; 178-024-822-765-048; 178-219-444-908-354; 184-956-537-068-371; 187-186-906-236-723; 198-642-877-607-139,4,true,cc-by,hybrid -040-027-555-447-051,Research Guides: Introduction to R Studio: Bibliometrix data file,2018-11-07,2018,libguide,,,,,Ameet Doshi,,,,,,Data file; Computer science; Studio; Multimedia,,,,,https://libguides.gatech.edu/c.php?g=890639&p=7866037,https://libguides.gatech.edu/c.php?g=890639&p=7866037,,,3203565616,,0,,0,false,, -040-142-016-043-895,A Systematic Bibliometric Analysis of the Real Estate Bubble Phenomenon: A Comprehensive Review of the Literature from 2007 to 2022,2023-08-23,2023,journal article,International Journal of Financial Studies,22277072,MDPI AG,,José-Francisco Vergara-Perucich,"This article presents the results of a bibliometric review of the study of real estate bubbles in the scientific literature indexed in Web of Science and Scopus, from 2007 to 2022. The analysis was developed using a sample of 2276 documents, which were reviewed in R software and analyzed with the assistance of the Bibliometrix package of the same software. The results indicate that there has been considerable productivity on the topic of real estate bubbles since 2007, with an emphasis on housing price formation processes and the social effects when bubbles burst. The authors found that there were not many case studies located in Latin America or Africa, nor were there approaches with advanced predictive modeling techniques using machine learning or artificial intelligence. The article provides an understanding of the state of the art in real estate bubble research and situates new research in front of the influential literature previously published.",11,3,106,106,Real estate; Scopus; Data science; Economic bubble; Computer science; Web of science; Bubble; Business; Political science; Finance; MEDLINE; Parallel computing; Law,,,,"Vicerrectoría de Investigación of Universidad de Las Américas, Chile",https://www.mdpi.com/2227-7072/11/3/106/pdf?version=1692764130 https://doi.org/10.3390/ijfs11030106,http://dx.doi.org/10.3390/ijfs11030106,,10.3390/ijfs11030106,,,0,004-338-759-590-231; 005-491-093-331-870; 009-286-240-384-618; 010-171-819-922-943; 013-317-445-487-622; 013-507-404-965-47X; 015-217-444-270-813; 015-950-652-740-682; 018-174-868-439-039; 020-606-354-006-891; 022-827-807-568-494; 023-292-061-353-646; 024-091-128-143-930; 024-261-785-133-547; 025-322-680-440-279; 025-487-528-665-364; 025-728-361-374-331; 033-127-677-566-360; 034-737-350-778-112; 044-680-506-908-883; 049-468-783-505-963; 050-206-292-036-790; 058-932-685-979-201; 065-485-482-604-786; 065-930-636-907-636; 065-978-264-892-607; 066-784-771-171-733; 067-420-954-452-297; 083-732-844-656-865; 086-771-766-095-679; 091-687-132-263-836; 096-061-214-240-715; 096-853-306-718-283; 109-726-720-389-508; 111-561-492-642-530; 120-975-417-040-341; 143-152-645-653-657; 154-576-547-323-548; 155-736-781-058-515,1,true,cc-by,gold -040-863-426-259-63X,Wildfires in Australia: a bibliometric analysis and a glimpse on 'Black Summer' (2019/2020) disaster.,2023-05-19,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,K M Shamsul Haque; Minhaz Uddin; Jeffrey Dankwa Ampah; Md Kamrul Haque; Md Shahadat Hossen; Md Rokonuzzaman; Md Yeamin Hossain; Md Sazzad Hossain; Md Zillur Rahman,"A wildfire, an unplanned fire that is mainly uncontrolled and originates in combustible vegetation in rural or urban settings, is one of the most pervasive natural catastrophes in some areas, such as Siberia, California and Australia. Many studies, such as standard reviews, have been undertaken to look into the works of literature on wildfires or forest fires and their effects on aquatic and terrestrial ecosystems. Regrettably, conventional literature reviews failed to identify the important researchers, evolving complexities, emerging research hotspots, trends and opportunities for further research on the ground of wildfire study. The present study employs bibliometric analysis to investigate this study area qualitatively and quantitatively. The Scopus database systems and Web of Science Core Collection yielded 78 qualifying papers, which were then evaluated using Biblioshiny (A bibliometrix tool of R-studio). According to the statistics, the discipline is expanding at a pace that is 13.68% faster than average. So far, three key periods of transformation have been documented: preliminary evolution (8 articles; 1999-2005), gentle evolution (14 articles; 2006-2013) and quick evolution (56 articles; 2014 to 2021). Forest Ecology and Management and Science journals have the highest number of publications, accounting for 7.70% of total wildfire-related articles published from 1999 to 2021. However, recent data indicate that investigators are shifting their focus to wildfires, with the term 'Australia' having the highest frequency (91) and 'wildfire' having the second highest (58) as the most appeared keywords. The present study will provide a foundation for future research on wildfire incidence and management by receiving information by synthesising previously published literature in Australia and around the world.",30,29,73061,73086,Geography; Scopus; Web of science; Pace; Environmental resource management; Natural disaster; Ecology; Environmental science; Meteorology; Political science; MEDLINE; Geodesy; Law; Biology,Australia; Bibliometric analysis; Biblioshiny; Bushfire; Wildfire,Wildfires; Ecosystem; Fires; Forests; Bibliometrics,,Charles Sturt University,https://link.springer.com/content/pdf/10.1007/s11356-023-27423-1.pdf https://doi.org/10.1007/s11356-023-27423-1 https://www.researchsquare.com/article/rs-2089340/latest.pdf https://doi.org/10.21203/rs.3.rs-2089340/v1,http://dx.doi.org/10.1007/s11356-023-27423-1,37202640,10.1007/s11356-023-27423-1,,PMC10195669,0,002-337-638-992-915; 003-087-949-694-904; 003-193-080-769-509; 003-380-201-818-56X; 004-022-701-971-698; 004-196-444-727-95X; 005-607-776-837-637; 006-005-338-598-697; 006-515-843-980-045; 006-867-590-371-08X; 008-243-344-005-751; 008-629-094-741-802; 008-787-584-026-741; 008-925-869-212-671; 009-738-654-244-150; 013-342-348-155-276; 013-507-404-965-47X; 014-183-451-689-090; 016-644-022-655-441; 016-880-140-167-048; 017-111-222-918-79X; 017-128-063-677-511; 018-632-833-266-831; 019-656-016-555-791; 020-036-726-443-91X; 020-492-344-595-941; 020-670-443-136-280; 021-013-372-731-766; 021-093-610-993-730; 021-677-028-748-069; 023-497-951-415-799; 023-793-512-470-792; 023-837-187-063-748; 024-596-916-563-518; 024-828-285-631-472; 025-340-222-381-186; 025-526-780-422-398; 025-587-575-037-30X; 026-429-525-941-985; 027-142-939-011-09X; 027-274-464-098-332; 027-361-510-759-169; 028-724-802-425-642; 029-189-448-167-816; 029-369-493-776-109; 030-419-773-863-467; 030-583-880-188-174; 030-688-911-580-111; 031-126-823-255-791; 034-326-874-919-047; 034-442-778-253-175; 034-658-158-500-326; 035-265-074-978-76X; 037-230-510-315-923; 038-376-312-152-367; 039-333-057-366-566; 039-958-098-001-459; 040-249-219-074-093; 041-163-198-522-123; 041-233-831-308-28X; 041-745-051-247-366; 042-424-965-686-495; 043-205-620-415-32X; 043-704-478-691-214; 044-247-228-337-824; 044-956-092-860-238; 044-980-706-151-648; 044-999-777-963-176; 045-422-273-148-899; 045-999-127-309-89X; 046-630-407-630-430; 046-733-800-988-860; 048-043-280-159-376; 048-612-190-946-744; 048-776-075-859-400; 049-325-930-931-818; 049-385-982-392-62X; 049-889-105-499-774; 050-268-598-975-751; 051-204-875-801-762; 051-394-934-034-744; 051-771-293-399-081; 052-141-971-252-100; 052-587-904-957-828; 053-638-547-862-25X; 054-031-328-268-264; 055-458-200-383-430; 055-697-282-150-603; 059-366-365-880-985; 060-990-565-771-69X; 061-764-351-575-31X; 063-272-157-067-719; 064-394-165-427-261; 064-995-777-849-354; 065-414-548-500-771; 066-590-672-402-932; 066-741-326-962-131; 068-116-571-155-922; 069-860-125-836-906; 069-969-511-177-258; 071-185-378-011-043; 071-878-836-294-733; 073-273-142-259-088; 075-611-780-243-509; 075-907-874-127-720; 076-231-968-914-724; 079-689-460-112-636; 081-243-124-575-450; 081-614-620-584-831; 082-791-581-127-446; 086-853-512-984-125; 087-302-220-831-157; 088-485-947-726-033; 088-678-638-590-073; 088-929-386-854-354; 093-826-506-259-672; 096-207-817-913-885; 097-103-743-415-188; 098-910-799-568-404; 099-549-405-577-108; 101-752-490-869-458; 102-674-577-744-768; 103-834-949-823-907; 104-495-326-573-684; 104-955-214-388-462; 107-773-427-002-721; 108-889-383-872-987; 110-014-532-995-463; 110-187-003-093-603; 112-036-725-073-641; 112-701-699-952-585; 112-726-309-563-885; 114-884-202-775-040; 115-509-488-949-449; 115-949-612-165-713; 116-225-276-648-689; 118-761-982-234-047; 122-302-332-180-253; 123-126-271-461-145; 125-844-162-169-62X; 126-019-233-920-799; 131-514-529-944-959; 134-461-339-447-882; 136-077-021-741-201; 137-495-116-924-48X; 141-878-431-357-967; 148-386-065-496-441; 151-089-595-776-587; 151-618-451-869-03X; 153-013-762-683-460; 154-891-076-182-741; 177-032-728-669-280,9,true,cc-by,hybrid -040-955-907-561-168,"Future of Energy Management Models in Smart Homes: A Systematic Literature Review of Research Trends, Gaps, and Future Directions",2025-04-01,2025,journal article,Process Integration and Optimization for Sustainability,25094238; 25094246,Springer Science and Business Media LLC,,Ubaid ur Rehman; Pedro Faria; Luis Gomes; Zita Vale,"Abstract; This paper presents a systematic literature review of energy management models for smart homes, conducted between 2018 and 2024, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. Smart homes leverage advanced technologies to optimize energy consumption and enhance sustainability through interconnected devices and sophisticated algorithms. The review covers energy optimization techniques, predictive management, renewable energy integration, demand-side management, user behavior, and data protection. It examines the effectiveness of various models, identifies key tends, and addresses challenges such as integrating diverse energy sources, managing consumption variability, and ensuring data privacy. The findings reveal significant advancements in energy optimization, home automation, and grid stability. However, areas like demand-side management and artificial intelligence (AI) and machine learning (ML) driven algorithms for energy management remain underexplored and require further research. Recommendations are provided to improve energy management systems and guide future research for increased efficiency and sustainability in smart homes. This review offers valuable insights into the current state of energy management models and lays the groundwork for future developments in smart home energy systems.",,,,,,,,,Fundação para a Ciência e a Tecnologia; Instituto Politécnico do Porto,,http://dx.doi.org/10.1007/s41660-025-00506-x,,10.1007/s41660-025-00506-x,,,0,002-406-724-604-188; 004-844-597-126-963; 006-187-128-570-186; 007-365-720-749-666; 007-440-065-465-110; 008-324-393-667-852; 009-901-085-313-554; 010-828-393-408-19X; 012-417-970-232-814; 013-507-404-965-47X; 014-468-535-539-89X; 014-818-365-445-037; 015-852-616-927-440; 016-611-684-674-894; 016-672-061-095-764; 016-866-376-314-04X; 017-300-737-144-757; 018-781-423-540-18X; 020-223-307-253-867; 023-307-222-812-17X; 024-120-417-295-607; 024-211-354-294-298; 026-164-939-809-502; 030-750-685-608-490; 030-911-677-909-618; 031-560-382-528-003; 032-182-686-749-623; 034-455-905-874-920; 034-763-028-210-747; 035-590-354-037-189; 036-791-565-493-130; 037-204-414-636-728; 037-252-311-287-648; 037-374-810-543-285; 039-628-741-840-613; 041-724-230-709-412; 042-164-723-577-87X; 042-844-136-566-657; 044-571-884-444-112; 045-361-485-433-062; 047-180-922-660-715; 049-028-156-344-858; 051-768-397-531-203; 054-166-459-052-453; 060-485-249-128-785; 060-604-748-135-129; 064-834-868-082-075; 065-529-705-732-26X; 067-058-094-421-490; 067-073-171-990-968; 068-188-754-082-394; 068-353-741-112-407; 069-439-253-193-66X; 069-969-734-963-424; 074-088-704-857-912; 077-936-106-806-515; 078-969-486-542-212; 079-066-795-712-851; 081-035-054-185-951; 083-957-117-954-10X; 085-160-807-448-831; 087-021-352-825-161; 087-493-084-007-001; 088-949-051-355-148; 091-019-233-675-000; 093-330-092-087-890; 093-571-949-025-232; 094-266-020-452-740; 095-010-794-686-636; 096-849-957-122-692; 097-593-492-046-166; 098-150-639-803-71X; 098-167-975-212-100; 098-445-381-270-650; 099-304-805-375-657; 100-915-975-324-795; 101-054-173-782-81X; 103-407-584-579-879; 103-718-419-679-612; 103-738-542-008-054; 107-300-639-625-787; 108-269-442-084-706; 109-719-362-340-505; 109-903-065-656-44X; 113-240-300-859-766; 114-390-098-687-517; 114-878-186-663-864; 115-417-423-982-995; 115-764-661-514-923; 117-599-223-437-282; 118-543-744-322-791; 121-745-180-776-07X; 126-195-296-678-867; 128-298-542-774-569; 128-350-724-691-081; 129-790-640-818-896; 129-791-257-252-812; 131-004-572-288-061; 133-662-102-503-019; 134-125-406-432-347; 134-803-675-259-116; 135-905-953-134-246; 136-657-320-068-273; 140-124-416-999-542; 140-412-202-021-369; 145-214-844-436-683; 146-880-907-858-308; 149-387-881-725-215; 150-929-521-938-566; 153-032-221-373-519; 155-239-250-684-085; 157-470-509-174-047; 158-444-562-856-044; 160-246-132-184-780; 161-588-081-623-62X; 165-292-745-390-674; 166-015-185-934-143; 167-797-885-951-070; 168-558-352-241-20X; 168-572-472-419-544; 171-112-318-714-554; 171-624-421-860-698; 171-867-539-674-934; 171-958-447-847-07X; 173-731-824-566-270; 176-304-989-228-723; 178-232-098-663-96X; 178-416-490-165-275; 182-190-102-375-701; 182-948-422-942-943; 185-457-943-494-130; 187-418-770-553-948; 187-518-960-441-988; 188-348-919-382-960; 191-209-207-678-008; 192-892-597-823-893; 198-165-385-054-348,0,true,cc-by,hybrid -040-956-354-079-236,Bibliometric analysis and mini-review of global research on pyroptosis in the field of cancer.,2023-04-18,2023,journal article,Apoptosis : an international journal on programmed cell death,1573675x; 13608185,Springer Science and Business Media LLC,Netherlands,Wenwen Wang; Wenhuizi Sun; Han Xu; Yao Liu; Chenlu Wei; Siqiao Wang; Shuyuan Xian; Penghui Yan; Jiajun Zhang; Hongjun Guo; Hengwei Qin; Jie Lian; Xiangyu Han; Jiaqi Zhang; Ruixia Guo; Jie Zhang; Zongqiang Huang,,28,7-8,1076,1089,Pyroptosis; China; Bibliometrics; Science Citation Index; Medicine; Programmed cell death; Political science; Citation; Library science; Computer science; Biology; Apoptosis; Biochemistry; Law,Global research; Gynecology; Inflammasomes; Prognosis; Pyroptosis,"Female; Humans; Apoptosis; Bibliometrics; Carcinogenesis; Cell Transformation, Neoplastic; Inflammasomes; Neoplasms/genetics; Pyroptosis/genetics",Inflammasomes,Shanghai Municipal Health Commission; Henan medical science and technology research project; Key project of provincial and ministerial co-construction of Henan Medical Science and Technology,,http://dx.doi.org/10.1007/s10495-023-01821-9,37071294,10.1007/s10495-023-01821-9,,,0,002-939-112-368-892; 003-153-833-646-639; 004-295-532-495-283; 006-303-769-437-305; 007-290-302-889-849; 007-324-393-010-088; 007-736-037-782-437; 008-231-716-013-86X; 008-384-405-940-874; 011-689-186-743-592; 013-507-404-965-47X; 013-999-540-550-432; 016-248-508-585-960; 016-625-746-071-675; 019-776-754-883-507; 019-819-098-483-480; 020-744-244-729-170; 021-105-291-848-952; 022-668-888-139-206; 024-137-823-537-414; 024-846-908-625-490; 025-408-474-683-808; 025-814-778-781-726; 027-307-097-134-175; 031-382-043-892-901; 031-741-420-707-954; 035-560-036-513-701; 038-441-280-829-481; 038-545-965-193-03X; 040-189-460-713-03X; 042-065-811-380-950; 043-977-506-192-45X; 045-924-160-956-398; 047-257-890-658-735; 051-135-554-801-685; 056-221-790-956-331; 057-624-181-416-359; 063-095-918-826-720; 064-264-938-557-557; 064-400-499-357-900; 065-303-633-752-584; 065-805-587-336-327; 066-374-930-131-359; 067-776-459-105-754; 071-985-543-971-79X; 072-042-364-654-214; 072-995-275-446-897; 073-609-322-213-227; 074-151-334-688-857; 080-389-658-565-033; 083-928-762-402-970; 085-454-204-097-415; 085-807-405-447-064; 091-105-794-426-275; 093-507-313-833-692; 098-327-844-749-979; 107-237-458-719-865; 108-335-160-701-115; 108-788-951-130-883; 116-414-962-959-770; 119-280-925-345-305; 126-509-512-507-288; 128-253-028-212-927; 129-003-382-839-866; 141-232-852-276-927; 155-134-308-450-724,4,false,, -041-158-241-630-028,Bibliometric analysis of pedagogy of death,2025-01-03,2025,journal article,Frontiers in Education,2504284x,Frontiers Media SA,,Anabel Ramos-Pla; Isabel del Arco; Pere Mercadé-Melé,"IntroductionThe objective of the present study is to identify the main emerging trends and research lines with respect to pedagogy of death.MethodsThe methodology was based on a bibliometric analysis of the main international scientific contributions found in the Web of Science (WoS) database. A total of 276 articles published between 2010 and 2023 were revised. The data were analyzed with VosViewer and Bibliometrix R which are software tools for building and visualizing bibliometric networks.ResultsThe main results show that the publications on pedagogy of death have increased through time, but decreased starting in 2020, both in the number of articles and citations.DiscussionScientific evidence is also presented on the need to continue working on pedagogy of death. This study contributes toward maximizing the visibility of pedagogy of death work in different contexts.",9,,,,Computer science; Mathematics education; Sociology; Psychology,,,,,,http://dx.doi.org/10.3389/feduc.2024.1502231,,10.3389/feduc.2024.1502231,,,0,000-635-786-299-146; 001-475-453-554-555; 002-842-319-111-663; 006-390-261-930-770; 008-279-114-393-618; 009-160-926-304-623; 010-503-308-388-898; 013-276-147-659-061; 015-421-147-281-231; 015-777-829-630-213; 015-855-513-419-121; 018-993-137-105-974; 019-971-516-456-044; 020-114-330-785-586; 020-776-799-379-369; 021-810-191-319-723; 022-577-956-385-932; 024-517-526-893-417; 027-058-981-974-883; 034-176-638-598-906; 040-634-699-401-444; 043-055-905-345-520; 043-697-701-893-992; 044-158-426-102-175; 044-875-954-486-08X; 048-459-704-566-741; 049-450-448-970-15X; 051-857-822-534-267; 052-209-376-225-472; 052-368-509-368-900; 058-338-696-761-409; 058-518-699-125-350; 059-197-642-811-669; 060-554-378-025-666; 070-237-880-908-855; 076-088-688-162-178; 080-776-724-250-33X; 081-472-653-871-713; 087-859-792-471-562; 088-038-778-821-392; 088-105-442-765-435; 097-864-400-401-098; 099-025-278-385-359; 101-840-011-672-851; 102-152-473-494-209; 108-378-435-612-948; 114-683-657-762-122; 119-287-247-439-995; 132-243-270-440-325; 132-308-279-448-387; 133-418-800-422-73X; 139-266-750-071-860; 153-090-570-995-661; 154-038-356-678-41X; 178-874-258-501-463; 182-651-772-342-983,0,true,cc-by,gold -041-373-221-184-27X,Internet das Coisas Aplicada aos Negócios: Análise das Publicações Utilizando o Bibliometrix / Internet of Things Applied to Business: Analysis of Publications Using Bibliometrix,2021-07-01,2021,journal article,Revista FSA,18066356; 23172983,Revista FSA,,Anderson Betti Frare; Alex Sandro Rodrigues Martins; Carla Milena Gonçalves Fernandes; Vagner Horz; Alexandre Costa Quintana,"Objetiva-se analisar as publicacoes sobre Internet of Things (IoT) no universo dos negocios, presentes na base da Web of Science. O portfolio de 2.632 documentos fora analisado no package Bibliometrix no software R. O maior numero de artigos concentra-se no IEEE ACCESS The Multidisciplinary Open Access Journal . Acerca dos autores e universidades mais proliferas, denota-se a predominância no continente asiatico. Em relacao aos artigos mais citados e as palavras-chave, evidencia-se a conexao entre os temas tecnologicos (automacao, sistemas e controle) e a facilitacao na gestao para as respectivas operacoes. Palavras-chave: Internet das Coisas. IoT. Negocios. Bibliometrix. ABSTRACT The aim is to analyze the publications about Internet of Things (IoT) in the business universe, present at the base of the Web of Science. The portfolio of 2,632 documents was analyzed in the Bibliometrix package in the R software. The largest number of papers is focused on the IEEE ACCESS The Multidisciplinary Open Access Journal. Among the most prolific authors and universities, there is a predominance in Asia. In relation to the most cited articles and the keywords, the connection between the technological themes (automation, systems and control) and the facilitation in the management of the respective operations. Keywords: Internet of Things. IoT. Business. Bibliometrix.",18,7,55,76,The Internet; Library science; Political science; Open access journal; R software; Web of science; Internet of Things,,,,,http://www4.unifsa.com.br/revista/index.php/fsa/article/view/2323/491492868 http://www4.unifsa.com.br/revista/index.php/fsa/article/download/2323/491492866,http://dx.doi.org/10.12819/2021.18.7.4,,10.12819/2021.18.7.4,3193654975,,0,,0,true,cc-by-nc-nd,gold -041-523-504-083-066,A bibliometric analysis of top-cited journal articles in interstitial cystitis and bladder pain syndrome.,2022-07-26,2022,journal article,International urogynecology journal,14333023; 09373462,Springer Science and Business Media LLC,Germany,Xing-Peng Di; Liao Peng; Li-Yuan Xiang; Meng-Hua Wang; Jie Zhang; De-Yi Luo,,33,9,2557,2563,Medicine; Interstitial cystitis; Bladder Pain Syndrome; Web of science; Citation; Bibliometrics; MEDLINE; Science Citation Index; Citation analysis; Urology; Gynecology; Internal medicine; Library science; Alternative medicine; Pathology; Meta-analysis; Computer science; Political science; Law,Bibliometric analysis; Bladder pain syndrome; Citation; Interstitial cystitis,"Bibliometrics; Cross-Sectional Studies; Cystitis, Interstitial; Gynecology; Humans; Urology",,,,http://dx.doi.org/10.1007/s00192-022-05298-z,35881178,10.1007/s00192-022-05298-z,,,0,000-773-981-554-267; 001-593-365-133-766; 006-948-792-948-881; 008-061-592-012-937; 013-772-772-516-480; 014-691-794-764-241; 016-105-102-873-024; 019-797-125-357-750; 021-032-554-522-328; 022-333-636-050-905; 022-981-206-351-922; 026-527-619-401-92X; 028-130-558-256-526; 031-921-351-218-361; 046-881-296-761-564; 050-019-476-926-807; 056-036-547-008-046; 057-957-300-796-768; 062-188-550-998-706; 062-769-754-070-729; 066-179-485-765-818; 066-721-801-247-105; 066-957-738-081-851; 068-519-128-890-355; 072-584-534-232-265; 083-081-248-196-325; 090-397-086-031-660; 093-296-413-685-255; 101-752-490-869-458; 115-849-204-062-338; 131-577-340-336-480; 141-214-364-453-999; 152-366-022-648-296,2,false,, -041-843-689-216-437,Six Sigma and the application perspectives of various industries: A bibliometric analysis,,2020,journal article,"International Journal of Advanced Engineering, Management and Science",24541311,AI Publications,,Kevin Luis Mendoza-Loyo; Sergio Vázquez-Rosas; Emma Isabel Caballero-López; Uriel Alejandro Hernández-Sánchez,"In recent years, quality in companies has become a priority issue which, according to the organization, is a matter of very little investment and dedication in the production lines, so a quality tool can be the solution to this problem. The present research work is to demonstrate the state of the art on Six Sigma and the perspectives in several industries through a bibliometric analysis using Bibliometrix. A database from Scopus is used, which includes a total of 857 articles in a time span from 2016 to 2020. From the results obtained, some characteristics of the articles are illustrated and analyzed (keywords, main authors, country of origin, main journals, scientific production and collaborative networks). The results obtained from the analysis show the existence of an exponential increase trend on Six sigma, being the basis for improving the quality of the processes.",6,12,565,570,Work (electrical); Six Sigma; Investment (macroeconomics); Lean Six Sigma; Country of origin; Quality (business); Bibliometric analysis; Computer science; Knowledge management; Scopus,,,,,http://journal-repository.com/index.php/ijaems/article/view/2949,http://dx.doi.org/10.22161/ijaems.612.12,,10.22161/ijaems.612.12,3116024965,,0,,0,true,cc-by,gold -042-151-027-336-017,Microgels and Nanogels at Interfaces and Emulsions: Identifying Opportunities From a Bibliometric Analysis,2021-10-20,2021,journal article,Frontiers in Physics,2296424x,Frontiers Media SA,,Miguel Angel Fernandez-Rodriguez; Laura Alvarez,"In this work, we used Bibliometrix and Biblioshiny to perform a bibliometric qualitative and quantitative analysis on the main topic ""microgels and nanogels"", and the sub-topic ""microgels and nanogels at interfaces and emulsions"". Word-counting of the titles of the publications enabled a descriptive analysis of thematic trends. A more complex conceptual analysis used the co-occurrence of words in titles, clustered into research themes with links to other themes. A thematic map allowed to characterize the centrality and density of the themes within the topic. A similar clustering of co-authorship enabled the mapping of the collaborations. We identified in this way research opportunities theme- and collaboration-wise.",9,,,,Sociology; Data science; Theme (narrative); Quantitative analysis (finance); Research opportunities; Bibliometric analysis; Descriptive statistics; Centrality; Cluster analysis; Thematic map,,,,Ministerio de Ciencia e Innovación; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung,https://www.frontiersin.org/articles/10.3389/fphy.2021.754684/full https://www.research-collection.ethz.ch/handle/20.500.11850/515064,http://dx.doi.org/10.3389/fphy.2021.754684,,10.3389/fphy.2021.754684,3207832442,,0,009-110-994-364-198; 013-507-404-965-47X; 013-524-854-219-241; 015-692-170-714-052; 045-319-398-508-266; 053-261-373-627-438; 058-909-459-782-878; 066-236-345-097-06X; 078-778-634-412-080; 085-399-964-851-805; 138-270-687-058-342; 142-608-256-821-705,4,true,cc-by,gold -042-160-054-482-348,Prior Steps into Knowledge Mapping: Text Mining Application and Comparison,2023-04-03,2023,journal article,Issues in Science and Technology Librarianship,10921206,University of Alberta Libraries,United States,Faizhal Arif Santosa,"Bibliometrics is increasingly being used by the knowledge community and librarians to easily analyze patterns in knowledge. In the field, the use of data from databases that provide bibliometric information is not always completely clean, so pre-processing is required. Several previous studies have shown that bibliometric analysis begins with a simple pre-processing step. The goal of this research is to use text mining to perform pre-processing to find the basic terms of the keywords that appear – to essentially construct a controlled vocabulary for a bibliographic dataset. The method used in this study is cleaning keywords with the stemming method using RapidMiner software. Bibliometrix was used to compare the results. A total of 85 keywords were combined into basic words. Using the built process, this study discovers differences in the network built between raw data and data that has been pre-processed, resulting in differences in the analysis that will be produced. The built process can also be reused in a variety of real-world situations.",,102,,,Computer science; Construct (python library); Field (mathematics); Bibliometrics; Process (computing); Vocabulary; Raw data; Information retrieval; Variety (cybernetics); Data science; Software; Simple (philosophy); Knowledge extraction; Data mining; Artificial intelligence; Mathematics; Linguistics; Philosophy; Epistemology; Operating system; Pure mathematics; Programming language,,,,,https://journals.library.ualberta.ca/istl/index.php/istl/article/download/2736/2724 https://doi.org/10.29173/istl2736,http://dx.doi.org/10.29173/istl2736,,10.29173/istl2736,,,0,005-229-324-676-654; 013-507-404-965-47X; 016-715-269-424-974; 017-511-023-957-609; 046-424-399-301-946; 049-391-379-302-694; 056-660-482-909-837; 059-530-013-678-793; 080-735-974-338-157; 128-156-730-150-282; 190-127-275-029-610; 198-431-032-845-178,2,true,cc-by-nc,gold -042-228-556-143-432,Perspective on secondary disasters: a literature review for future research,2024-10-24,2024,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Kübra Yazıcı Sahın; Bahar Yalcın Kavus; Alev Taskın,,,,,,Perspective (graphical); Sustainable development; Engineering ethics; Environmental planning; Political science; Geography; Engineering; Computer science; Artificial intelligence; Law,,,,,,http://dx.doi.org/10.1007/s10668-024-05577-3,,10.1007/s10668-024-05577-3,,,0,001-309-942-734-828; 002-052-422-936-00X; 004-297-120-456-180; 006-199-670-842-469; 006-625-884-534-17X; 006-977-844-965-644; 007-173-573-135-579; 007-258-983-443-198; 008-515-134-439-224; 009-500-711-897-415; 009-932-368-211-875; 011-016-514-550-073; 011-469-980-064-998; 012-073-893-542-619; 012-833-175-145-730; 013-419-975-149-740; 013-507-404-965-47X; 014-490-160-238-986; 014-581-168-248-488; 018-649-753-570-623; 020-768-887-646-084; 022-531-621-079-876; 023-821-554-850-879; 028-732-100-224-889; 030-455-981-482-86X; 033-789-593-569-858; 033-989-683-020-443; 034-247-997-850-646; 037-347-740-780-758; 040-755-007-751-971; 042-989-701-527-958; 044-051-490-258-430; 046-260-702-860-428; 047-134-478-431-993; 047-973-753-212-312; 051-020-818-788-18X; 051-134-109-813-763; 052-315-213-789-942; 053-623-202-121-980; 053-729-708-909-041; 060-236-402-612-147; 061-162-923-337-520; 064-785-293-244-927; 065-460-494-613-750; 066-923-775-823-636; 067-700-083-737-858; 068-586-682-970-360; 071-946-982-316-672; 073-565-990-260-692; 073-905-961-780-208; 078-862-145-276-278; 079-630-714-676-524; 081-100-276-166-789; 081-678-585-631-93X; 081-688-338-262-179; 084-988-765-676-37X; 085-652-555-358-59X; 086-482-704-029-237; 087-350-697-902-393; 087-395-706-249-007; 088-744-508-552-979; 091-673-671-812-93X; 095-439-639-160-695; 096-573-546-476-918; 097-679-233-220-788; 098-751-922-657-811; 100-393-894-574-092; 102-373-122-377-704; 103-940-295-893-445; 103-940-902-024-867; 105-756-078-337-429; 107-099-247-443-755; 109-496-800-208-614; 111-806-962-783-892; 115-663-923-643-15X; 117-267-014-282-455; 118-717-497-783-706; 122-691-804-236-182; 125-068-405-909-858; 125-203-096-044-959; 126-509-177-497-886; 126-800-466-101-220; 126-835-819-169-213; 130-610-520-994-400; 139-077-648-102-525; 149-844-755-384-086; 150-301-537-623-928; 151-629-926-464-380; 152-260-015-334-605; 154-378-883-552-908; 157-689-461-570-628; 159-034-690-612-233; 161-555-947-575-286; 161-679-941-769-009; 168-444-098-583-363; 169-632-307-097-383; 170-708-404-700-520; 198-780-820-460-098,0,false,, -042-577-630-638-886,Current landscape of the enterprise resource planning (ERP) research: A bibliometric review,,2022,conference proceedings article,AIP Conference Proceedings,0094243x; 15517616; 19350465,AIP Publishing,,Aidi Ahmi; Siti Zabedah Saidin,"Enterprise Resource Planning (ERP) is a type of integrated business management software that allows a company to gather, store, manage, and understand data from various business processes. Many studies have explored about it implementations and success among big conglomerates. This study aims to explore the current landscape of the ERP studies from the perspective of the form of publications, trends, and conceptual structure using bibliometric analysis in order to recognize the extent of ERP studies that have been explored till now. Biblioshiny, a Bibliometrix R package tool, was used to examine the current form of publication and the knowledge structure in ERP. A search query on the Scopus database using the term ""enterprise resource planning"" was performed, retrieving 1,232 scholarly articles from 1992 to 2021. Bibliometric results indicate that the studies on this research field are growing steadily.",2644,,30005,030005,Enterprise resource planning; Computer science; Scopus; Knowledge management; Implementation; Resource (disambiguation); Field (mathematics); Data science; Perspective (graphical); Process management; Business; Software engineering; Political science; Computer network; Mathematics; MEDLINE; Artificial intelligence; Pure mathematics; Law,,,,,https://aip.scitation.org/doi/pdf/10.1063/5.0106544 https://doi.org/10.1063/5.0106544,http://dx.doi.org/10.1063/5.0106544,,10.1063/5.0106544,,,0,002-019-778-763-109; 010-078-538-944-672; 012-188-848-835-017; 013-507-404-965-47X; 015-138-868-000-432; 019-890-455-291-658; 026-245-240-911-233; 026-641-635-034-137; 026-771-226-472-596; 028-135-944-424-770; 028-563-208-561-305; 038-911-250-952-554; 043-818-150-665-640; 045-368-114-501-494; 045-551-085-665-021; 051-219-528-978-960; 054-471-776-222-314; 062-254-663-282-117; 066-796-816-334-195; 071-251-171-804-778; 075-364-301-587-828; 082-705-882-006-10X; 098-620-070-333-197; 101-385-081-193-694; 107-145-503-644-172; 114-037-499-717-791; 123-202-581-406-928; 124-753-295-414-123; 134-040-828-587-901; 143-319-821-608-583; 161-500-729-494-834; 162-489-186-623-434,0,true,,bronze -042-738-935-402-30X,Research trends and highlights in PD-1/PD-L1 inhibitor immunotherapy in lung cancer: a bibliometric analysis.,2025-03-11,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Zheng Gu; Erle Deng; Jing Ai; Fei Wu; Qiang Su; Junxian Yu,"Lung cancer is one of the most common malignant tumors worldwide. This article aims to review the current research status and trends in PD-1/PD-L1 inhibitor immunotherapy.; On the basis of the Web of Science Core Collection database, literature on PD-1/PD-L1 inhibitor immunotherapy in lung cancer patients was searched and analyzed for all years up to August 5, 2023. Bibliometric techniques were employed, including CiteSpace (6.1.R6), VOSviewer, and the Bibliometrix package in R, to examine publication counts, countries, institutions, authors, journals, cited literature, keywords, and research trends.; A total of 1,252 documents were included following the screening process. The analysis revealed that China had the highest number of publications (512), whereas the institution with the most publications was the UDICE French Association of Research Universities Union (193). The journal with the most articles was the Journal for Immunotherapy of Cancer (48), and the most prolific author was Zhou Caixun from Tongji University in China (20). Co-citation analysis revealed that Borghaei H's 2015 article in the New England Journal of Medicine had the highest citation frequency. The clustering results indicated that the most frequently referenced keywords included predictors, treatment monitoring, and hyperprogressive diseases. There is a growing trend toward combination therapies, such as dual immune checkpoint inhibitors, and research into molecular mechanisms within the tumor microenvironment, aimed at enhancing the efficacy of immunotherapy and reducing adverse effects.; Bibliometric analysis indicates that PD-1/PD-L1 inhibitors are pivotal in lung cancer immunotherapy. Research in this domain focuses on identifying biomarkers within the tumor microenvironment, addressing immune evasion and resistance to maximize efficacy, and mitigating adverse effects.; © 2025. The Author(s).",16,1,292,,Lung cancer; Immunotherapy; Medicine; Cancer; Internal medicine; Cancer immunotherapy; Citation; Oncology; Library science; Computer science,Bibliometrics; Immunotherapy; Lung cancer; PD-1/PD-L1,,,,,http://dx.doi.org/10.1007/s12672-025-02052-x,40064803,10.1007/s12672-025-02052-x,,PMC11893958,0,000-210-265-189-933; 000-496-651-829-798; 002-852-159-123-460; 003-771-844-984-180; 004-819-850-909-888; 007-647-277-406-364; 013-100-945-095-847; 013-312-659-053-667; 015-657-751-707-172; 019-541-405-328-250; 020-322-005-558-271; 020-499-468-025-07X; 022-703-574-575-508; 027-603-120-661-00X; 030-311-515-115-306; 030-316-328-713-442; 038-153-773-365-180; 038-178-412-107-566; 041-643-631-590-710; 044-776-532-451-668; 045-911-376-256-566; 050-888-540-726-186; 051-355-619-019-796; 053-716-406-771-689; 061-210-361-928-639; 067-399-354-042-485; 068-416-071-545-291; 068-945-392-083-431; 072-721-513-792-683; 073-062-628-509-331; 090-258-862-206-647; 095-308-196-564-403; 107-093-100-655-457; 107-483-302-885-238; 109-214-771-980-059; 115-562-794-324-327; 169-773-027-625-259,0,true,cc-by,gold -042-884-662-222-682,Sustainable land use and management research: a scientometric review,2020-03-31,2020,journal article,Landscape Ecology,09212973; 15729761,Springer Science and Business Media LLC,United States,Hualin Xie; Yanwei Zhang; Xiaoji Zeng; Yafen He,,35,11,2381,2411,Land degradation; Land use land-use change and forestry; Business; Emerging technologies; Sustainability science; Sustainable land management; Land use; Sustainable development; Sustainability; Environmental planning,,,,Innovative Research Group Project of the National Natural Science Foundation of China,https://link.springer.com/article/10.1007/s10980-020-01002-y,http://dx.doi.org/10.1007/s10980-020-01002-y,,10.1007/s10980-020-01002-y,3014736367,,0,000-352-744-189-424; 001-554-753-147-797; 001-719-026-803-199; 003-240-409-434-94X; 005-282-941-882-296; 006-808-502-767-966; 007-409-428-164-945; 008-676-342-371-671; 010-635-988-181-034; 011-974-751-288-346; 012-467-413-787-29X; 013-507-404-965-47X; 015-079-377-260-195; 015-639-556-404-695; 016-375-162-349-910; 016-635-754-643-29X; 018-401-060-200-700; 019-325-242-619-654; 019-586-721-838-489; 020-019-480-536-336; 020-727-019-740-336; 021-584-890-955-435; 027-136-530-659-041; 027-274-585-305-510; 030-066-624-600-400; 030-094-962-131-895; 030-687-895-806-920; 032-999-172-139-947; 033-648-918-097-117; 035-013-574-415-866; 035-850-431-686-333; 037-406-635-951-161; 037-734-588-445-41X; 039-466-400-216-928; 040-743-819-429-461; 043-470-617-955-955; 044-522-318-254-129; 045-641-282-546-653; 049-360-683-113-159; 049-614-408-147-773; 055-956-013-020-927; 056-002-925-128-630; 056-511-223-277-530; 058-634-622-743-263; 061-696-630-095-544; 061-705-526-688-392; 065-108-368-829-080; 065-409-334-539-500; 066-827-251-380-184; 067-565-431-298-005; 068-036-345-349-403; 068-718-897-814-578; 072-288-446-398-859; 073-237-422-583-781; 073-931-162-868-384; 075-325-104-765-793; 078-544-894-847-222; 089-370-370-337-266; 093-500-256-712-306; 093-906-305-232-940; 093-988-126-016-742; 097-577-849-846-909; 098-074-362-814-675; 098-292-012-860-714; 101-777-262-752-590; 105-061-379-478-507; 116-378-896-347-665; 118-508-523-599-689; 120-509-587-069-608; 128-217-524-056-953; 131-085-258-249-07X; 133-983-651-417-794; 135-108-859-435-331; 135-453-540-530-502; 136-861-540-966-794; 140-463-743-001-15X; 142-877-194-782-944; 147-041-736-569-331; 152-761-167-084-188; 155-072-877-630-919; 161-072-580-272-396; 168-160-900-919-983; 168-799-379-837-756; 169-315-535-267-226; 182-553-054-049-556,124,false,, -042-915-258-738-379,Research performance of a Peruvian medical students' scientific society in Scopus and Web of Science: a bibliometric analysis of Sociedad Científica de San Fernando,2023-01-01,2023,dataset,Figshare,,,,Alvaro Quincho-Lopez,"These datasets provide raw data for the analysis of the scientific production of medical students from a single university in Peru. The csv. format and text.txt can be analyzed with Bibliometrix R-tool and VOSviewer, and many other programs. The other tab delimited.txt can be analyzed with other online softwares.",,,,,Scopus; Web of science; Library science; Data science; Computer science; Political science; MEDLINE; Law,,,,,https://figshare.com/articles/dataset/Untitled_ItemResearch_performance_of_a_Peruvian_medical_students_scientific_society_in_Scopus_and_Web_of_Science_a_bibliometric_analysis_of_Sociedad_Cient_fica_de_San_Fernando/24036627,http://dx.doi.org/10.6084/m9.figshare.24036627,,10.6084/m9.figshare.24036627,,,0,,0,true,cc-by,gold -042-931-434-061-230,Kamu Harcamaları ve Ekonomik Büyüme İlişkisinin Bibliyometrik Analizi: VOSviewer ve R (Bibliometrix) Örneği,2024-12-12,2024,journal article,İzmir İktisat Dergisi,13088505; 13088173,Izmir Iktisat Dergisi,,Mustafa Gökmenoğlu; İsmail Sadık Yavuz,"Kamu harcamaları ve ekonomik büyüme ilişkisi iktisadın sistematik bir bilim haline geldiğinden beri tartışılmıştır. İki değişken arasındaki etkileşim sadece insanları değil toplumları ve hatta ülkeleri etkilemiştir. İki kavram arasında oluşan sinerji beraberinde refah artışını da getirmiştir. Bu özellikleri 1960’lı yıllardan bu yana iktisat disiplinin önemli araştırma konuları halinden birisi olmalarında önemli bir rol oynamıştır. Bu çalışmanın amacı da iktisat disiplini içerisinde söz konusu değişkenlerin ilişkilerini inceleyen çalışmaların birbirleriyle olan ilişkilerinin literatürde ne boyutta olduğunu ve gelişiminin araştırılmasıdır. Bir diğer önemli husus ise çalışmanın günümüz projeksiyonunu çıkartarak elde edilen bulguların potansiyel araştırmacılara ışık tutmasını ve yol göstermesini sağlamaktır. Bu kapsamda elde edilen sonuçlar yayınların yerel ve uluslararası ağları ve ilişkileri değerlendirilmiştir. Ağa az sayıda yazarın ve kaynağın uluslararası boyutta literatüre oldukça büyük katkılar yaptığı buna ek olarak ağa katkı sağlayan gelişmiş ve gelişmekte olan ülkeler arasında farklılıklar bulunduğu tespit edilmiştir. Analizlerden elde edilen bir diğer önemli husus ise yazarların genel olarak tek ülkeli yayınlar yaptığı ve bu bağlamda konu özelinde istenilen düzeyde uluslararası ilişkilerin kurulamadığı tespit edilmiştir.",39,4,1027,1048,Humanities; Mathematics; Art,,,,Süleyman Demirel Üniversitesi,https://dergipark.org.tr/tr/download/article-file/3656749 https://dergipark.org.tr/tr/pub/ije/issue/88062/1418943,http://dx.doi.org/10.24988/ije.1418943,,10.24988/ije.1418943,,,0,000-667-231-896-402; 002-052-422-936-00X; 005-046-805-027-741; 010-291-770-326-88X; 013-507-404-965-47X; 017-750-600-412-958; 019-292-437-817-986; 019-704-491-230-658; 023-688-902-597-006; 028-630-476-231-596; 030-860-731-750-701; 032-434-007-753-320; 034-768-039-318-254; 042-474-047-254-816; 049-391-379-302-694; 050-620-415-061-78X; 053-422-649-943-859; 061-202-126-245-002; 071-903-355-299-99X; 072-123-175-750-607; 074-823-231-228-646; 076-794-879-020-832; 083-878-937-843-725; 090-731-522-534-055; 097-541-486-782-891; 100-841-662-749-929; 121-057-159-845-799; 132-821-755-491-464; 132-946-951-460-277; 137-091-170-243-318; 159-306-125-917-84X,0,true,cc-by-nc,gold -043-219-516-358-019,Neuroeconomía: una revisión basada en técnicas de mapeo científico,2021-02-15,2021,journal article,"Revista de Investigación, Desarrollo e Innovación",23899417; 20278306,Universidad Pedagogica y Tecnologica de Colombia (Hipertexto-Netizen),,Damiand Felipe Trejos-Salazar; Pedro Luis Duque-Hurtado; Luz Alexandra Montoya-Restrepo; Iván Alonso Montoya-Restrepo,"Neuroeconomics is a multidisciplinary field, which articulates the knowledge of areas such as economics, psychology and neuroscience, and which studies brain behavior in decision-making. Through a literature review, the evolution of research in neuroeconomics is presented. For this, scientific mapping techniques are used, supported by bibliometric tools. The search was carried out in the WoS and Scopus databases, and the information obtained was processed with the Bibliometrix and Gephi tools. The documents were classified according to their relevance, into three categories: classic, structural and current. Then, through an analysis of co-citations and clustering, five lines or currents of research in the area were identified and analyzed, namely: economic choices, social choice, considerations on neuroeconomics, consumer neuroscience and behavior and brain stimulation . It concludes with the need to find and standardize a research methodology, in which the criteria converge to strengthen the results of the research carried out, since the limitations of current methodologies cannot be ignored.",11,2,243,260,Psychology; Neuroeconomics; Social choice theory; Multidisciplinary approach; Data science; Consumer neuroscience; Brain stimulation; Field (computer science); Scopus; Relevance (information retrieval),,,,,https://facminas-unalmed.demo.elsevierpure.com/en/publications/neuroeconom%C3%ADa-una-revisi%C3%B3n-basada-en-t%C3%A9cnicas-de-mapeo-cient%C3%ADfico https://dialnet.unirioja.es/descarga/articulo/7944848.pdf http://www.scielo.org.co/pdf/ridi/v11n2/2389-9417-ridi-11-02-243.pdf https://dialnet.unirioja.es/servlet/articulo?codigo=7944848 http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S2027-83062021000100243,http://dx.doi.org/10.19053/20278306.v11.n2.2021.12754,,10.19053/20278306.v11.n2.2021.12754,3173622712,,0,,21,true,cc-by,gold -043-419-424-162-47X,Deciphering the impact of machine learning on education: Insights from a bibliometric analysis using bibliometrix R-package,2024-05-06,2024,journal article,Education and Information Technologies,13602357; 15737608,Springer Science and Business Media LLC,United Kingdom,Zilong Zhong; Hui Guo; Kun Qian,,29,16,21995,22022,Educational technology; Computer science; Science education; Mathematics education; Data science; Knowledge management; Psychology,,,,Zhejiang Provincial Philosophy and Social Science Planning Project; Double First-Class Disciplines Project of Beijing Foreign Studies University,,http://dx.doi.org/10.1007/s10639-024-12734-8,,10.1007/s10639-024-12734-8,,,0,004-392-115-121-939; 013-507-404-965-47X; 016-018-072-562-245; 018-109-926-408-687; 021-344-105-745-174; 023-458-128-504-785; 025-674-718-713-906; 032-727-400-084-476; 032-951-028-740-321; 037-119-112-124-878; 037-832-913-411-31X; 039-209-418-791-114; 041-666-295-567-491; 044-804-588-703-508; 046-992-864-415-70X; 047-004-056-135-638; 048-101-937-906-923; 049-391-379-302-694; 057-760-331-432-992; 065-657-822-536-010; 068-016-753-152-548; 069-354-235-672-04X; 070-293-257-947-330; 070-708-457-505-15X; 072-520-962-660-917; 074-607-647-699-656; 080-148-742-683-174; 085-685-552-029-310; 088-757-574-801-921; 092-105-949-873-632; 096-087-138-649-847; 096-484-077-273-602; 099-651-628-607-504; 101-317-679-377-995; 105-337-581-994-921; 113-416-164-653-427; 116-915-738-528-146; 127-979-033-092-380; 140-396-481-794-462; 142-380-235-064-989; 143-562-055-691-487; 144-544-265-616-327; 144-792-878-444-081; 146-349-583-646-037; 148-725-926-860-73X; 150-300-265-385-238; 152-358-363-470-676; 153-353-112-024-392; 155-092-147-639-936; 157-429-904-751-268; 178-376-135-073-225; 179-964-893-193-274; 188-911-646-913-067; 190-338-622-952-128; 190-750-733-593-994,9,false,, -043-879-774-085-379,Bibliometrix Analysis: Management Inventory dan Supply Management,2023-10-10,2023,journal article,eCo-Fin,2656095x; 26560941,Komunitas Dosen Indonesia,,Hariyanto Hariyanto; Riki Riki,"Inventory and Supply Management is an important aspect of efficient business operations. Both are interrelated and have an impact on achieving competitive advantage and customer satisfaction. In the case study of PT. Berkahjaya Sentosa Technique, Bibliometrix analysis is used to evaluate the performance of inventory and supply management of companies. The results show that effective inventory and supply management can improve operational efficiency and customer satisfaction. Bibliometrics is an analytical method used to map and analyze scientific literature in a particular field. In the context of inventory management and distribution control, bibliometrics can provide valuable insight into the development and focus of study in a particular field. The purpose of this study is to analyze and summarize scientific literature related to inventory management and distribution control using bibliometric methods. The method used is descriptive analysis using analysis tools such as three-field plots and tables of main information. The results show that scientific literature related to inventory management and distribution control has experienced a decline in annual growth in the period 2018-2023. However, the average citation per document shows that this literature is still very relevant and important in the context of inventory management and distribution control. This research provides valuable insights for researchers and practitioners in the field of inventory management and distribution control",5,3,223,236,Bibliometrics; Context (archaeology); Inventory control; Control (management); Scientific literature; Distribution management system; Computer science; Process management; Operations management; Business; Marketing; Engineering; Geography; Data mining; Paleontology; Archaeology; Artificial intelligence; Biology; Electrical engineering,,,,,https://jurnal.kdi.or.id/index.php/ef/article/download/870/506 https://doi.org/10.32877/ef.v5i3.870,http://dx.doi.org/10.32877/ef.v5i3.870,,10.32877/ef.v5i3.870,,,0,,0,true,cc-by-sa,hybrid -044-015-610-610-93X,Research progress and hotspots on microbial remediation of heavy metal-contaminated soil: a systematic review and future perspectives.,2023-11-08,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Xianhong Li; Yang Gao; Xiaolin Ning; Zhonghong Li,,30,56,118192,118212,Environmental remediation; Soil remediation; China; Soil contamination; Environmental science; Environmental engineering science; Web of science; Environmental resource management; Environmental planning; Earth science; Ecology; Political science; Biogeosciences; Contamination; Soil water; Biology; Soil science; MEDLINE; Geology; Law,Heavy metal-contaminated soil; Microbial remediation; Scientometric analysis; Web of Science,"Humans; Environmental Pollution; Hazardous Substances; Environmental Restoration and Remediation; Metals, Heavy; Soil","Hazardous Substances; Metals, Heavy; Soil",,,http://dx.doi.org/10.1007/s11356-023-30655-w,37936038,10.1007/s11356-023-30655-w,,,0,001-701-902-860-770; 001-830-138-452-43X; 002-052-422-936-00X; 002-390-343-617-643; 002-871-886-558-755; 003-609-673-971-178; 008-073-834-317-935; 009-504-544-885-406; 013-507-404-965-47X; 014-067-175-453-162; 015-168-119-692-678; 017-018-090-201-407; 018-282-075-300-14X; 019-609-716-896-421; 019-813-693-899-133; 019-914-386-905-209; 023-008-277-662-906; 024-647-283-955-374; 026-369-619-270-981; 027-688-897-286-54X; 028-188-969-492-568; 028-353-109-117-131; 028-662-600-549-726; 029-067-325-472-436; 032-496-613-879-824; 033-894-602-405-594; 034-660-229-303-26X; 035-770-741-719-807; 036-329-736-247-621; 036-860-788-568-984; 036-865-734-009-32X; 037-052-663-253-410; 039-988-897-904-889; 043-654-584-958-67X; 045-377-491-337-399; 046-588-323-847-038; 051-659-617-023-68X; 056-229-288-394-472; 056-247-314-930-54X; 061-332-865-383-236; 064-400-499-357-900; 068-290-289-611-991; 070-337-791-127-297; 070-766-209-492-455; 070-767-973-668-860; 071-015-669-042-50X; 072-143-566-858-605; 079-458-804-274-463; 079-679-789-158-219; 081-520-319-494-792; 086-331-288-209-969; 088-444-910-094-502; 088-691-563-914-497; 091-658-869-998-957; 093-422-683-929-568; 093-559-686-650-527; 094-349-752-962-651; 094-561-023-658-834; 095-173-225-458-146; 096-797-525-960-471; 097-483-794-230-260; 101-752-490-869-458; 102-215-600-986-43X; 105-379-160-316-685; 109-663-662-108-96X; 118-103-307-957-300; 127-315-704-035-562; 127-700-737-446-115; 129-851-523-717-654; 133-572-363-676-429; 140-754-540-068-610; 158-138-388-478-352; 165-549-580-834-695; 174-266-624-421-427; 177-282-721-127-448; 186-596-887-962-10X; 186-627-624-477-494; 191-770-906-024-007; 192-571-432-639-775,10,false,, -044-034-843-760-06X,Crowdfunding platforms: a systematic literature review and a bibliometric analysis,2023-04-29,2023,journal article,International Entrepreneurship and Management Journal,15547191; 15551938,Springer Science and Business Media LLC,Germany,Alexandra Mora-Cruz; Pedro R. Palos-Sanchez,"Due to the financial crisis caused by the COVID-19 pandemic, entrepreneurs and small businesses have had multiple difficulties accessing conventional types of financing. Crowdfunding platforms have gained popularity as an alternative means of online financing. The main objective of this research is to analyze the most important articles that may influence future studies on crowdfunding platforms in Latin America. This article analyzes the Scopus and Web of Science databases considering three of the four categories of crowdfunding based on capital flows: Reward, Equity, and Lending, using a systematic review of the literature and bibliometric analysis. This research resulted in a total of 1032 articles which, after applying the appropriate criteria, resulted in 55 selected articles. The results show that the number of studies conducted in the field of crowdfunding platforms is increasing. Crowdfunding platforms provide a great opportunity for entrepreneurs to obtain alternative financing and a new way for investors to invest their capital. Future lines of research include conducting studies that involve a stronger focus on the technology used in crowdfunding platforms. With systematized access to information, the different actors can understand how the dynamics of crowdfunding platforms can stimulate the development of business projects, as well as the decision-making factor when investing. This document is of great interest to researchers and professionals who wish to increase their knowledge of crowdfunding platforms, especially those of Reward, Equity, and Lending, in addition to gaining knowledge on relevant conclusions and suggestions for future research.",19,3,1257,1288,Scopus; Popularity; Equity crowdfunding; Venture capital; Entrepreneurship; Business; Equity (law); Marketing; Finance; Seed money; Public relations; Political science; MEDLINE; Law,,,,,https://link.springer.com/content/pdf/10.1007/s11365-023-00856-3.pdf https://doi.org/10.1007/s11365-023-00856-3,http://dx.doi.org/10.1007/s11365-023-00856-3,,10.1007/s11365-023-00856-3,,,0,000-691-064-117-060; 001-095-312-780-909; 002-461-026-242-038; 005-442-441-206-208; 007-820-510-354-596; 008-456-039-923-168; 009-594-664-279-736; 010-173-885-130-070; 010-359-500-786-673; 010-584-763-831-385; 013-507-404-965-47X; 014-283-883-018-846; 015-449-615-192-198; 016-015-929-879-353; 016-543-942-541-102; 017-303-972-646-582; 017-750-600-412-958; 020-169-638-414-325; 029-612-916-666-954; 030-879-699-987-812; 034-660-781-742-338; 035-303-447-537-444; 036-950-845-964-22X; 040-085-053-608-180; 042-637-673-661-340; 044-201-223-809-024; 048-313-592-552-836; 049-896-351-797-350; 051-723-314-130-406; 052-958-357-019-954; 056-952-559-351-611; 057-433-617-492-722; 057-795-984-515-20X; 061-443-600-175-273; 063-493-286-193-147; 063-621-987-257-012; 063-971-402-547-058; 065-722-830-561-628; 067-863-118-496-254; 075-143-914-106-557; 075-784-696-463-344; 075-972-510-378-570; 081-698-047-397-814; 081-922-339-489-853; 082-125-096-568-374; 083-297-380-596-37X; 084-307-706-951-072; 087-090-231-487-249; 092-416-635-997-593; 100-977-776-923-393; 102-203-920-505-203; 107-772-581-477-616; 110-409-458-348-511; 113-216-898-086-656; 114-206-974-827-549; 117-234-074-007-550; 117-806-700-772-77X; 119-433-358-698-845; 120-974-286-046-262; 121-393-018-395-969; 128-917-338-311-620; 134-181-543-786-906; 137-815-404-264-084; 139-512-341-366-650; 145-313-846-965-11X; 149-678-841-655-849; 153-108-877-433-279; 176-010-535-784-633; 177-659-053-875-340; 189-265-854-840-678,23,true,,bronze -044-080-430-301-452,Scientometric portrait of Professor CNR Rao using bibliometrix R package,,2020,journal article,Library Herald,00242292; 09762469,Diva Enterprises Private Limited,,Samir Kumar Jalal,,58,2and3,94,,Art; Portrait; R package; Art history,,,,,http://dx.doi.org/10.5958/0976-2469.2020.00026.3,http://dx.doi.org/10.5958/0976-2469.2020.00026.3,,10.5958/0976-2469.2020.00026.3,3094013044,,0,,1,false,, -044-135-212-623-563,Silvicultura de Precisão e o setor florestal: Uma abordagem bibliométrica,,2023,journal article,Série Técnica IPEF,27643808,Instituto de Pesquisa e Estudos Florestais (IPEF),,Vinvivenci Filipe Pereira de Lima e Silva; Josiana Jussara Nazaré Basílio; Anny Francielly Ataide Gonçalves; Fernanda Leite Cunha; Otávio Camargo Campoe,,26,48,449,453,Political science,,,,,,http://dx.doi.org/10.18671/sertec.v26n48.089,,10.18671/sertec.v26n48.089,,,0,,0,true,,bronze -044-406-736-338-570,Bibliometric Analysis of Multi-Level Perspective on Sustainability Transition Research,2022-03-31,2022,journal article,Sustainability,20711050,MDPI AG,Switzerland,Cheng Wang; Tao Lv; Rongjiang Cai; Jianfeng Xu; Liya Wang,"The multi-level perspective (MLP) is a prominent framework for transition research. However, few studies have used bibliometrics for conducting a global picture of the MLP research. This study identifies the worldwide trends at three levels: sources, authors, and documents, and uses the bibliometrix based on 757 articles published in WOS and Scopus from 2002 to 2020. The results show that the MLP research literature is proliferating, and the number of journals and countries concerned in this field is increasing. MLP research has mainly focused on transition, sustainability transition, socio-technical transition, energy transition, innovation, and governance; and will increase focus on agency, power, and policy. MLP research will focus on multi-niche, multi-regime, and multi-landscape interactions at the hierarchy levels. The results assist scholars in systematically understanding the current research status, research frontiers, and future trends of MLP from a macro perspective.",14,7,4145,4145,Scopus; Bibliometrics; Sustainability; Agency (philosophy); Hierarchy; Perspective (graphical); Transition (genetics); Corporate governance; Data science; Political science; Regional science; Management science; Social science; Sociology; Computer science; Data mining; Economics; Management; Artificial intelligence; Ecology; Biochemistry; Chemistry; MEDLINE; Biology; Gene; Law,,,,National Natural Science Foundation of China; National Social Science Foundation of China; the project of Carbon Neutrality & Energy Strategy Think Tank; General Project of Philosophy and Social Science Research in Universities of Jiangsu Province; Jiangsu Social Science Foundation Project,https://www.mdpi.com/2071-1050/14/7/4145/pdf?version=1648707252 https://doi.org/10.3390/su14074145,http://dx.doi.org/10.3390/su14074145,,10.3390/su14074145,,,0,001-411-163-575-929; 002-052-422-936-00X; 002-592-081-602-227; 003-665-299-702-184; 005-426-183-939-758; 005-737-143-194-163; 006-197-388-803-395; 006-250-402-432-253; 007-035-385-097-135; 007-270-189-300-511; 009-286-240-384-618; 009-308-976-247-872; 009-354-611-524-256; 009-493-142-740-078; 009-522-993-541-667; 011-120-134-686-665; 011-265-791-542-909; 013-455-524-813-743; 013-507-404-965-47X; 013-903-540-100-07X; 014-199-208-535-477; 015-654-226-226-641; 016-034-585-828-790; 017-163-708-232-979; 019-626-286-897-743; 020-955-929-008-907; 021-960-059-348-715; 021-990-768-929-149; 022-155-073-597-480; 022-293-709-458-693; 022-840-598-070-724; 022-893-188-764-335; 022-903-046-826-226; 026-562-998-167-910; 026-651-546-374-083; 026-660-170-876-409; 027-842-615-215-624; 029-850-024-596-958; 030-631-599-946-600; 031-149-978-904-970; 031-588-162-913-713; 032-208-806-219-68X; 032-213-172-789-766; 032-618-237-242-979; 034-863-562-969-751; 037-696-960-426-457; 038-588-290-420-993; 038-876-315-074-035; 039-133-922-855-924; 039-725-772-868-71X; 040-117-023-931-503; 040-444-176-783-378; 043-810-319-055-551; 044-092-200-129-384; 044-933-946-718-795; 044-972-891-950-918; 045-096-214-947-788; 045-112-141-870-624; 046-536-260-575-789; 046-573-036-799-860; 046-714-111-439-221; 047-545-845-603-280; 048-857-136-508-941; 050-552-331-402-645; 051-647-739-244-271; 052-661-535-212-312; 053-206-548-028-057; 054-579-077-621-695; 055-183-108-926-13X; 060-345-661-272-418; 062-439-049-108-232; 063-403-412-914-653; 065-479-363-333-740; 066-174-271-836-454; 068-926-107-407-780; 071-595-428-623-083; 073-371-388-568-904; 074-426-669-329-960; 075-004-097-669-017; 076-358-413-838-260; 078-490-311-135-629; 080-009-469-215-125; 081-124-566-543-737; 082-365-909-796-079; 082-762-437-732-868; 083-790-282-298-618; 083-952-386-846-155; 085-072-725-039-671; 085-080-698-242-42X; 085-459-378-860-903; 086-194-535-784-322; 087-069-503-769-295; 087-697-387-465-653; 088-414-448-215-329; 088-638-808-526-933; 090-491-221-614-123; 091-094-910-756-837; 092-163-899-683-456; 094-005-223-140-039; 095-934-640-552-117; 096-115-626-811-773; 099-474-556-129-907; 101-075-167-824-297; 101-187-026-513-985; 106-031-198-491-20X; 106-349-278-411-871; 113-104-968-050-565; 114-431-279-473-241; 116-298-385-323-565; 121-469-547-924-967; 122-416-895-258-62X; 122-681-000-702-88X; 123-910-495-659-571; 126-588-794-254-933; 126-966-675-992-699; 127-298-795-634-947; 135-783-858-406-685; 137-260-703-049-61X; 143-893-365-088-102; 144-316-790-427-925; 144-319-833-420-840; 145-890-476-463-402; 146-781-719-997-040; 148-096-291-025-431; 149-692-155-166-587; 151-049-633-518-321; 151-097-054-357-603; 154-976-454-698-191; 161-451-416-501-29X; 161-858-228-065-368; 166-838-380-906-508; 167-259-755-475-83X; 169-588-565-459-142; 173-973-923-051-784; 182-690-362-923-744,19,true,,gold -044-685-059-929-350,Data Privacy in Retail: A Bibliometric Analysis,2023-09-24,2023,journal article,Revista Interdisciplinar de Marketing,16769783,Universidade Estadual de Maringa,,Alina Flores; Lucas Dorneles,"Data privacy is an issue that is catching the attention of the retail research area, especially with the technological advances in data collection and analysis that impact the consumer's perception of safety. As publications on this subject have increased significantly in recent years, a review of academic knowledge is needed. In order to address this, our study conducts a comprehensive review of the privacy literature. Our investigation of the intersection between data privacy and retail literature is a bibliometric analysis. In this paper, 31 years of publications were collected from two sources of bibliographic databases: Web of Science and Scopus, with 413 articles in total. To facilitate our analyses, we use the Bibliometrix package in R language. Our analysis revealed that this is a subject growing in size and relevance, but the intellectual structure of the field is fragmented. We also discussed, based on the conceptual structure of the publications, ideas for future research regarding privacy and retail.",13,2,154,172,Scopus; Subject (documents); Relevance (law); Data science; Order (exchange); Web of science; Computer science; Field (mathematics); Business; World Wide Web; Political science; MEDLINE; Mathematics; Finance; Pure mathematics; Law,,,,,https://periodicos.uem.br/ojs/index.php/rimar/article/download/66702/751375156491 https://doi.org/10.4025/rimar.v13i2.66702,http://dx.doi.org/10.4025/rimar.v13i2.66702,,10.4025/rimar.v13i2.66702,,,0,,0,true,,gold -044-960-907-655-094,Job satisfaction and burnout among healthcare employees: a bibliometric analysis before and after Covid-19 pandemic,2025-05-13,2025,journal article,Quality & Quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,S. Porkodi; Sonal Pundhir,,,,,,Burnout; Pandemic; Coronavirus disease 2019 (COVID-19); Job satisfaction; Health care; 2019-20 coronavirus outbreak; Psychology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Nursing; Medicine; Political science; Social psychology; Clinical psychology; Virology; Outbreak; Disease; Pathology; Infectious disease (medical specialty); Law,,,,,,http://dx.doi.org/10.1007/s11135-025-02187-7,,10.1007/s11135-025-02187-7,,,0,000-457-195-745-758; 002-243-562-367-402; 002-553-192-990-021; 002-596-427-175-559; 005-202-446-246-767; 005-575-992-079-953; 007-643-411-291-775; 009-826-917-807-489; 011-495-242-743-20X; 013-507-404-965-47X; 018-250-202-466-112; 019-764-117-584-856; 022-297-967-491-128; 029-789-695-643-321; 030-445-893-679-604; 031-329-257-628-740; 031-531-051-422-754; 032-152-377-847-855; 032-425-111-137-937; 035-083-772-339-60X; 035-989-983-302-445; 038-594-266-837-386; 039-926-509-706-511; 040-110-057-557-239; 041-879-837-857-602; 043-327-112-746-814; 049-935-965-291-847; 051-172-915-192-241; 051-720-046-820-65X; 057-504-905-203-409; 057-730-309-417-836; 058-816-634-096-152; 062-238-598-239-63X; 065-010-405-236-060; 069-585-113-860-665; 069-615-784-139-611; 075-804-541-582-360; 077-018-819-049-259; 080-389-743-929-639; 088-201-679-167-820; 088-473-853-957-094; 088-894-260-284-088; 090-013-875-656-705; 096-907-717-158-402; 099-227-230-408-289; 099-650-256-973-997; 100-009-698-154-067; 102-207-778-954-742; 104-595-499-449-778; 116-339-119-777-116; 130-018-162-899-784; 133-254-208-614-187; 134-663-810-060-432; 134-863-520-208-060; 140-878-855-548-330; 144-492-702-983-028; 150-572-350-061-392; 154-860-885-877-488; 155-222-743-527-378; 158-830-766-042-443; 163-344-435-477-669; 171-162-772-106-706,0,false,, -045-079-551-866-394,Global research dynamics in urea cycle disorders: a bibliometric study highlighting key players and future directions.,2025-03-04,2025,journal article,Orphanet journal of rare diseases,17501172,Springer Science and Business Media LLC,United Kingdom,Yan Wang; Xueer Wang; Huiqin Zhang; Binhui Zhu,"This study aims to explore the research hotspots and trends of urea cycle disorders through bibliometric analysis.; Using the Web of Science Core Collection as the database, we retrieved literature published from 2007 to 2024. We utilized CiteSpace, VOSviewer, and Bibliometrix R package to conduct a bibliometric visualization analysis, including the number of publications, citation frequency, publishing countries, institutions, journals, authors, references, and keywords.; A total of 926 publications on UCDs were published in 318 journals by 4807 authors at 1494 institutions from 49 countries/regions. The USA had the highest number of publications and citation frequency. The Children's National Health System in the USA published the most literature. The most frequent collaboration was between the USA and Germany. The journal with the most publications was Molecular Genetics and Metabolism. The author with the most publications was Johannes Häberle. The most frequently cited reference was the 2019 publication of the revised guidelines for the diagnosis and management of UCDs. The identified future research hotspots are expected to focus on ""gene therapy"", ""mutations"" and ""efficacy"".; This study is the first bibliometric analysis of publications in the field of UCDs. These findings suggest that European and American countries dominate UCD research, it is necessary to further strengthen global cooperation in the field of UCDs. Early detection of the disease and emerging therapies, including gene therapy, are likely to be future research hotspots.; © 2025. The Author(s).",20,1,101,,Urea cycle; Key (lock); Human genetics; Bibliometrics; Computer science; Biology; Library science; Genetics; Computer security; Amino acid; Arginine; Gene,Bibliometric analysis; CiteSpace; Inborn errors of metabolism; Urea cycle disorder; VOSviewer,"Bibliometrics; Humans; Urea Cycle Disorders, Inborn; Biomedical Research",,,https://ojrd.biomedcentral.com/counter/pdf/10.1186/s13023-025-03625-3 https://doi.org/10.1186/s13023-025-03625-3,http://dx.doi.org/10.1186/s13023-025-03625-3,40038740,10.1186/s13023-025-03625-3,,PMC11881408,0,006-277-554-780-185; 008-582-645-948-493; 011-301-822-302-672; 017-182-213-410-618; 017-329-187-370-15X; 021-286-370-426-497; 023-984-683-207-755; 027-367-617-919-06X; 027-742-318-007-695; 029-580-574-393-197; 032-312-457-503-673; 036-875-029-849-429; 039-881-635-632-668; 040-509-866-604-247; 046-307-049-508-303; 046-784-412-424-182; 055-674-069-476-928; 055-862-725-925-794; 063-281-945-008-845; 072-406-735-339-075; 078-591-694-448-560; 083-798-287-069-538; 084-733-416-764-449; 087-382-013-827-959; 089-300-756-117-932; 091-466-913-835-965; 094-106-531-364-715; 095-731-824-281-681; 097-246-751-278-636; 098-576-870-038-414; 099-266-281-160-211; 123-202-581-406-928; 131-030-510-796-633; 134-627-028-236-479; 137-166-525-749-697; 144-321-172-773-173; 162-545-431-733-754; 162-808-933-303-203; 164-350-864-407-113; 165-781-424-451-568,0,true,"CC BY, CC0",gold -045-332-567-234-339,Use of Internet of Things in the Tourism and Hospitality Realm: A Descriptive Bibliometric Study using Bibliometrix R - Tool,2023-03-02,2023,conference proceedings article,2023 Second International Conference on Electronics and Renewable Systems (ICEARS),,IEEE,,Ajit Kumar Singh; Pankaj Kumar Tyagi; Afshan Irshad; Anita Kumari Singh; Priyanka Tyagi; Balraj Benedict,"In the tourism and hotel industry, the Internet of Things (IoT) is recognized for its potential to create new business opportunities. With IoT, the tourism and hospitality industries can leverage technology to enhance customer experiences, streamline operations, and increase profitability. This study analyses 188 articles related to the Internet of Things (IoT) that were published between 2010 and 2022, and sourced from Scopus database. The bibliometric tool ""biblioshiny"" was used to analyze the data and examine annual publications, authorship, sources, keywords, and citations. Results revealed a significant increase in annual scientific production and the average number of citations per document over the past decade. From 2015 to 2000, keywords like internet, management, model, technology, progress, networks and cities dominated the research. From 2020 onwards, researchers have shown their interest in the keywords of challenges, industry, behavior, big data, system and architecture.",,,619,626,Tourism; Realm; Scopus; The Internet; Hospitality; Internet of Things; Profitability index; Hospitality industry; Leverage (statistics); Big data; Business; Data science; World Wide Web; Hospitality management studies; Computer science; Marketing; Knowledge management; Geography; Political science; Data mining; Archaeology; MEDLINE; Finance; Machine learning; Law,,,,,,http://dx.doi.org/10.1109/icears56392.2023.10085341,,10.1109/icears56392.2023.10085341,,,0,012-074-127-184-511; 012-103-780-490-837; 013-881-579-488-580; 025-766-620-039-00X; 034-732-576-971-22X; 037-304-879-143-104; 037-780-139-213-768; 039-403-317-572-456; 040-072-228-915-05X; 053-442-253-090-325; 059-634-220-877-126; 067-783-233-742-131; 091-539-196-096-999; 099-829-140-690-071; 133-088-822-388-262,2,false,, -045-368-114-501-494,Sustainable Tourism in the Open Innovation Realm: A Bibliometric Analysis,2019-11-03,2019,journal article,Sustainability,20711050,MDPI AG,Switzerland,Valentina Della Corte; Giovanna Del Gaudio; Fabiana Sepe; Fabiana Sciarelli,"This study evaluates bibliometric analysis of sustainable tourism in the open innovation realm, depicts emerging themes, and offers critical discussion for theory development and further research. Through the use of bibliometrix, this paper investigates the amount of studies conducted in this area and verifies if such studies have represented a contribution to the evolving research in the field of sustainable tourism. Specifically, the paper identifies whether and to what extent scholars have explored these interconnections and maps to get to a conceptual structure of the field under investigation. The results identify the development status and the leading trends in terms of impact, main journals, papers, topics, authors, and countries. The analysis and the graphical presentations are crucial, as they can help both researchers and practitioners to better understand the state of the art of sustainable tourism in the experiential and digital era.",11,21,6114,,Open innovation; Development theory; Political science; State (polity); Sustainable tourism; Realm; Field (Bourdieu); Bibliometric analysis; Experiential learning; Knowledge management,,,,,https://unora.unior.it/handle/11574/192733 https://www.cabdirect.org/cabdirect/abstract/20203504977 https://ideas.repec.org/a/gam/jsusta/v11y2019i21p6114-d283064.html https://www.mdpi.com/2071-1050/11/21/6114/pdf https://www.mdpi.com/2071-1050/11/21/6114 https://doaj.org/article/0f070280fcbf4adba2a6437e24b8ee05 https://core.ac.uk/download/pdf/327121566.pdf,http://dx.doi.org/10.3390/su11216114,,10.3390/su11216114,2987973915,,0,000-792-009-951-071; 000-930-868-404-394; 002-545-857-380-448; 005-274-945-896-716; 005-436-054-427-042; 006-123-894-057-573; 006-473-844-880-035; 008-580-776-950-455; 010-416-963-679-266; 011-800-926-962-727; 011-899-303-237-951; 013-507-404-965-47X; 014-176-463-352-844; 014-358-697-719-829; 014-818-146-260-956; 015-289-369-722-578; 016-655-706-124-813; 017-226-312-356-575; 017-349-318-774-487; 017-750-600-412-958; 018-999-487-574-479; 020-841-784-951-914; 024-159-240-996-552; 025-028-463-228-91X; 025-717-605-766-507; 027-428-384-406-605; 027-880-771-260-897; 028-686-643-922-873; 030-881-718-550-943; 031-087-113-644-558; 031-189-885-754-818; 032-328-271-181-991; 032-559-158-553-640; 032-658-053-420-95X; 033-916-519-882-44X; 034-904-148-716-271; 035-176-799-876-707; 036-001-908-351-128; 036-848-538-704-144; 036-951-819-673-466; 038-680-901-725-983; 040-020-413-809-676; 041-918-547-825-302; 044-424-127-610-46X; 044-563-873-269-101; 045-422-273-148-899; 047-134-478-431-993; 047-510-743-617-358; 047-881-290-887-12X; 047-982-557-408-777; 049-481-684-912-447; 050-651-634-898-098; 050-955-468-334-299; 051-862-424-436-262; 052-023-984-116-223; 052-688-460-015-970; 054-695-074-940-066; 055-079-601-095-819; 055-686-199-825-426; 056-527-363-836-249; 064-443-874-974-952; 066-849-661-222-258; 067-456-603-759-590; 069-573-810-922-085; 072-029-496-622-250; 073-357-109-821-946; 074-080-300-205-671; 075-106-515-685-173; 075-301-866-096-796; 075-990-743-392-516; 076-504-519-216-163; 077-679-328-874-818; 081-373-328-464-459; 082-947-554-501-031; 083-115-037-010-079; 088-548-977-579-930; 090-385-768-259-998; 090-656-176-661-424; 090-675-308-429-779; 093-787-968-865-029; 094-453-991-634-567; 095-440-541-274-369; 097-597-973-843-439; 097-775-636-196-989; 098-377-939-800-955; 099-244-695-938-436; 099-560-434-782-263; 102-018-233-291-667; 102-316-464-612-726; 108-187-090-576-600; 114-814-697-502-402; 116-172-738-724-468; 117-024-497-712-061; 117-494-065-145-960; 117-835-461-431-363; 119-789-986-772-126; 120-974-286-046-262; 120-984-438-980-054; 126-321-787-826-857; 127-580-512-767-74X; 129-681-622-125-751; 130-057-480-639-007; 130-839-499-178-040; 137-229-009-810-952; 137-612-041-987-514; 138-549-187-402-459; 147-023-625-223-646; 147-537-741-681-394; 151-565-086-394-753; 151-956-567-214-395; 156-415-541-949-588; 159-328-101-041-684; 160-972-584-972-020; 163-175-642-699-876; 165-115-018-379-527; 165-795-016-075-804; 167-243-343-949-449; 167-919-343-604-712; 170-925-622-359-931; 176-565-900-904-752; 181-281-063-379-01X; 185-728-033-350-850; 191-339-983-912-894,152,true,cc-by,gold -045-729-878-498-273,Editorial of the Special Issue from WorldCIST'20.,2022-04-01,2022,editorial,Computational and mathematical organization theory,1381298x; 15729346,Springer Science and Business Media LLC,Netherlands,Inês Domingues; Ana Filipa Sequeira,,29,4,1,506,Computer science,,,,,https://link.springer.com/content/pdf/10.1007/s10588-022-09361-4.pdf https://doi.org/10.1007/s10588-022-09361-4,http://dx.doi.org/10.1007/s10588-022-09361-4,35382529,10.1007/s10588-022-09361-4,,PMC8972705,0,005-329-072-175-826; 005-482-895-179-474; 021-541-617-930-157; 024-470-079-790-09X; 038-227-840-715-830; 118-940-000-098-546; 164-532-317-995-072,0,true,,bronze -045-764-261-793-962,Current perspectives and emerging trends in iodine-125 seed implantation: a comprehensive bibliometric analysis.,2025-06-03,2025,journal article,Japanese journal of radiology,1867108x; 18671071,Springer Science and Business Media LLC,Germany,Zhao Liu; Qinghua Zhang; Xiancun Hou; Wei Shen; Yuan Zhu; Hui Zhu; Zhiyong Li,"Iodine-125 (125-I) seed implantation is a widely used brachytherapy technique for treating various solid tumors. This study aims to provide a bibliometric analysis of the research trends, key contributors, and emerging hotspots in this field.; A comprehensive search was conducted using the Web of Science Core Collection, covering publications from January, 1960 to August 20, 2024. Bibliometric analysis was performed with VOSviewer, CiteSpace, and the R package ""bibliometrix"" to examine trends in publications, countries, institutions, journals, authors, and keywords.; The analysis included 2212 publications, showing a steady increase in research output, with USA, China, and Japan leading in publication volume. The University of California System and Keio University were the most productive institutions. Brachytherapy and the International Journal of Radiation Oncology, Biology, and Physics emerged as the most influential journals in this field. Yorozu Atsunori and Wang Junjie were identified as key authors. Keyword co-occurrence analysis highlighted ""cancer,"" ""brachytherapy,"" and ""radiotherapy"" as core themes. Keyword burst analysis revealed evolving research hotspots, such as ""hepatocellular carcinoma,"" ""efficacy,"" ""safety,"" and ""transarterial chemoembolization,"" emphasizing concerns about long-term outcomes, safety, and treatment strategies for 125-I implantation therapy across multiple cancers.; This bibliometric analysis underscores that research on 125-I seed implantation is primarily focused on optimizing dosimetry, improving implantation techniques, and addressing long-term outcomes and safety. The findings emphasize the need for standardized treatment protocols to ensure consistent and effective clinical practice.; © 2025. The Author(s).",,,,,,Bibliometrics; Brachytherapy; Iodine-125 seed; Neoplasms; Radiotherapy; VOSviewer,,,,,http://dx.doi.org/10.1007/s11604-025-01805-6,40459697,10.1007/s11604-025-01805-6,,,0,001-774-478-246-997; 002-052-422-936-00X; 005-611-208-884-277; 006-859-866-120-75X; 007-429-258-700-861; 009-642-952-719-154; 016-604-903-012-503; 019-455-178-641-560; 023-037-116-751-88X; 032-100-491-580-993; 038-198-094-108-931; 042-368-526-454-197; 044-265-374-968-391; 047-655-856-482-194; 053-282-610-683-760; 053-750-816-931-218; 058-376-931-582-361; 062-788-832-811-910; 066-862-574-304-841; 067-635-710-683-10X; 072-805-066-522-283; 077-354-859-401-184; 082-002-136-133-210; 093-439-029-044-811; 096-907-717-158-402; 101-041-743-172-712; 101-752-490-869-458; 110-281-630-123-569; 126-446-575-097-735; 126-692-784-099-546; 131-256-128-483-435; 149-525-548-412-20X; 166-400-369-722-664; 186-559-577-981-492,0,true,cc-by,hybrid -046-100-087-838-065,LÓGICA FUZZY NA DECISÃO PRÁTICA PARA CONTROLE DE VERMINOSE EM CAPRINOS,,2022,journal article,Revista SODEBRAS,18093957,Revista SODEBRAS,,W. P. S. Oliveira; N. P. S. Santos; M. B. Oliveira; A. M. Araújo,"The professional nurse, when dealing with a patient, often experiences adverse situations in their work environment. This can affect their health. In order to know about this daily life, the present study aimed to carry out a bibliometric analysis on the theme Burnout in nurses where, in a more punctual way, we sought to identify the main predictors of Burnout of this profession from recent international publications. In the first part of the study, the software R (bibliometrix package) was used. Burnout predictors were identified from the articles resulting from the bibliometric search. The survey results pointed to an increase in publications over the years with a peak in 2018. The largest contributions in quantitative terms are still from the United States of America. Burnout predictors have an organizational and relational origin. Individual aspects, such as resilience, appear in a relevant way to avoid professional illness.",17,197,70,77,Biology,,,,,http://www.alice.cnptia.embrapa.br/bitstream/doc/1143864/1/Logica-fuzzy-na-decisao-pratica2022.pdf http://www.alice.cnptia.embrapa.br/alice/handle/doc/1143864,http://dx.doi.org/10.29367/issn.1809-3957.17.2022.197.70,,10.29367/issn.1809-3957.17.2022.197.70,,,0,,0,true,,gold -046-108-330-484-073,BIBLIOMETRIX PEMBELAJARAN BAHASA DI SEKOLAH DASAR,2023-01-25,2023,journal article,JISPE: Journal of Islamic Primary Education,27745619; 27743934,Institut Daarul Quran,,Muhammad Asip; Likus Likus; Dirhan Dirhan; Voettie Wisataone,"This study aims to see the development of research on language learning in elementary schools. This type of research is included in the type of literature review research. Research data sourced from Scopus. In the Scopus search column, data was found as many as 1,357,373 articles. The data was selected in four stages, namely identification, screening, eligibility, and included so that 26 articles were obtained for data processing. The process of interpreting the data is carried out with the help of R studio type 386.4.1.3. The results obtained are data with three categories of research information, namely authors, document searches, and documents. Based on the results of the study, it can be concluded that language learning in elementary schools is growing rapidly in the USA and the United Kingdom. Meanwhile, the most popular place to publish language learning articles is the journal of speech. For popular vocabulary in research, namely learning and linguistics",3,2,99,112,Scopus; Vocabulary; Computer science; Publication; Mathematics education; Natural language processing; Psychology; Linguistics; Political science; Philosophy; MEDLINE; Law,,,,,https://jurnal.idaqu.ac.id/index.php/jispe/article/download/89/68 https://doi.org/10.51875/jispe.v3i2.89,http://dx.doi.org/10.51875/jispe.v3i2.89,,10.51875/jispe.v3i2.89,,,0,,0,true,,bronze -046-206-115-102-609,From economic wealth to well-being: exploring the importance of happiness economy for sustainable development through systematic literature review,2024-05-23,2024,journal article,Quality & Quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Shruti Agrawal; Nidhi Sharma; Karambir Singh Dhayal; Luca Esposito,"AbstractThe pursuit of happiness has been an essential goal of individuals and countries throughout history. In the past few years, researchers and academicians have developed a huge interest in the notion of a ‘happiness economy’ that aims to prioritize subjective well-being and life satisfaction over traditional economic indicators such as Gross Domestic Product (GDP). Over the past few years, many countries have adopted a happiness and well-being-oriented framework to re-design the welfare policies and assess environmental, social, economic, and sustainable progress. Such a policy framework focuses on human and planetary well-being instead of material growth and income. The present study offers a comprehensive summary of the existing studies on the subject, exploring how a happiness economy framework can help achieve sustainable development. For this purpose, a systematic literature review (SLR) summarised 257 research publications from 1995 to 2023. The review yielded five major thematic clusters, namely- (i) Going beyond GDP: Transition towards happiness economy, (ii) Rethinking growth for sustainability and ecological regeneration, (iii) Beyond money and happiness policy, (iv) Health, human capital and wellbeing and (v) Policy push for happiness economy. Furthermore, the study proposes future research directions to help researchers and policymakers build a happiness economy framework.",58,6,5503,5530,Happiness; Sustainable development; Well-being; Systematic review; Economics; Political science; Psychology; MEDLINE; Social psychology; Law,,,,Università degli Studi di Salerno,https://link.springer.com/content/pdf/10.1007/s11135-024-01892-z.pdf https://doi.org/10.1007/s11135-024-01892-z,http://dx.doi.org/10.1007/s11135-024-01892-z,,10.1007/s11135-024-01892-z,,,0,000-208-954-892-912; 001-725-948-005-83X; 004-606-473-357-504; 004-756-001-221-354; 007-415-843-451-301; 007-470-341-365-683; 008-975-893-286-57X; 010-665-698-344-111; 013-507-404-965-47X; 013-993-633-619-390; 014-299-571-738-031; 014-348-029-877-873; 017-695-524-061-041; 025-302-119-966-613; 025-345-735-059-603; 025-695-628-256-847; 026-526-336-536-045; 027-858-406-091-561; 029-825-059-687-089; 031-024-227-140-114; 031-038-793-615-329; 031-857-067-929-680; 034-025-362-774-340; 034-600-684-728-898; 035-649-564-398-023; 035-685-678-225-655; 035-952-823-973-793; 038-445-760-154-83X; 041-298-927-280-258; 042-884-438-615-326; 046-992-864-415-70X; 047-220-552-776-692; 048-345-617-045-870; 049-531-155-738-511; 054-681-148-527-673; 054-854-557-029-547; 055-001-884-465-620; 055-977-667-556-619; 056-561-118-491-426; 058-064-226-367-76X; 058-767-950-650-567; 060-384-016-205-417; 062-115-579-804-840; 063-584-731-742-452; 064-808-356-780-866; 067-018-671-057-697; 068-555-534-337-211; 069-483-029-792-973; 072-023-026-792-59X; 076-455-283-385-797; 081-042-514-433-983; 081-733-589-932-210; 083-077-488-993-209; 083-137-544-456-89X; 086-050-808-164-83X; 086-691-858-626-334; 090-835-475-707-537; 091-774-980-461-62X; 092-406-102-017-370; 093-561-306-772-702; 098-096-986-556-288; 099-408-293-337-097; 100-215-245-592-117; 105-646-589-401-624; 107-792-201-522-613; 110-707-740-459-392; 113-716-567-907-270; 120-810-519-775-829; 123-972-285-872-28X; 124-252-537-628-63X; 126-219-096-391-953; 130-136-922-252-594; 130-243-184-541-960; 134-343-544-886-115; 135-160-447-218-283; 139-354-099-853-07X; 142-105-911-241-498; 153-392-213-243-449; 153-454-670-259-009; 155-428-625-195-433; 160-119-920-521-854; 162-775-219-332-340; 163-674-071-191-02X; 166-181-046-495-535; 166-486-634-960-322; 169-284-859-556-666; 179-404-190-821-451; 187-371-849-033-093,3,true,cc-by,hybrid -046-327-117-791-197,Does electric vehicle adoption (EVA) contribute to clean energy? Bibliometric insights and future research agenda,,2023,journal article,Cleaner and Responsible Consumption,26667843,Elsevier BV,,Divya Singh; Ujjwal Kanti Paul; Neeraj Pandey,"Clean sources of energy are a priority area for many organizations. The regulators and government are incentivizing these initiatives, which would also aid in achieving sustainable development goals (SDGs). Electric vehicle adoption (EVA) is an important pillar of clean energy which would help establish a sustainable transportation ecosystem in a nation. This study aims to comprehend the global trends in research on EVA since the 1980s. The bibliometric insights highlight that there has been a growing interest in EVA since early 2010, which is reflected in the number of publications and scholars conducting research in this domain. A corpus of 1077 research papers on EVA was analyzed using Vosviewer, Gephi, and Bibliometrix tools. The study maps the entire intellectual structure that covers EV adoption by individuals, organizations, and society. The study also proposes research agenda for future researchers working in the field of promotion of cleaner and sustainable transportation.",8,,100099,100099,Promotion (chess); Sustainable development; Pillar; Government (linguistics); Clean energy; Sustainability; Business; Environmental economics; Sustainable energy; Sustainable transport; Marketing; Economics; Political science; Engineering; Renewable energy; Ecology; Linguistics; Philosophy; Electrical engineering; Structural engineering; Politics; Law; Biology,,,,,,http://dx.doi.org/10.1016/j.clrc.2022.100099,,10.1016/j.clrc.2022.100099,,,0,000-289-376-192-777; 001-606-844-013-796; 002-052-422-936-00X; 003-063-831-571-494; 003-098-668-704-321; 004-735-446-206-816; 004-819-527-814-707; 007-063-942-626-916; 008-751-578-389-883; 011-301-822-302-672; 013-507-404-965-47X; 017-616-514-839-94X; 018-113-957-766-155; 018-769-143-370-778; 023-278-099-563-306; 023-927-221-065-800; 025-405-597-817-884; 026-052-525-951-182; 029-420-167-353-195; 031-803-817-086-51X; 032-281-714-070-196; 032-874-539-522-063; 036-237-629-965-611; 037-397-882-557-768; 042-700-714-770-287; 046-358-044-476-955; 046-992-864-415-70X; 052-570-207-268-321; 052-827-004-234-755; 054-818-565-070-154; 054-887-106-936-093; 055-737-049-590-665; 057-376-786-223-306; 057-829-996-601-781; 063-253-742-749-91X; 065-516-419-444-125; 066-133-112-740-761; 066-328-363-631-72X; 069-641-354-281-369; 071-878-836-294-733; 072-997-642-221-040; 075-360-355-793-928; 075-731-392-878-808; 076-612-133-611-556; 076-785-360-799-910; 084-622-639-038-67X; 086-248-118-072-35X; 107-294-051-396-217; 107-576-197-990-492; 110-928-702-682-568; 113-783-980-821-040; 114-368-494-085-39X; 123-098-278-899-734; 124-104-744-357-583; 128-261-427-858-258; 136-659-794-906-83X; 144-470-296-041-360; 148-698-319-015-808; 152-764-047-679-615,24,true,"CC BY, CC BY-NC-ND",gold -046-338-901-659-329,Current status and trend of global research on the pharmacological effects of emodin family: bibliometric study and visual analysis.,2025-01-10,2025,journal article,Naunyn-Schmiedeberg's archives of pharmacology,14321912; 00281298,Springer Science and Business Media LLC,Germany,Miao Luo; Luorui Shang; Jiao Xie; Tao Zhou; Chengyi He; David Fisher; Khrystyna Pronyuk; Erkin Musabaev; Nguyen Thi Thu Hien; Huan Wang; Lei Zhao,,398,6,6165,6178,Emodin; China; Web of science; Traditional medicine; Alternative medicine; Medicine; Political science; Meta-analysis; Pathology; Biology; Biochemistry; Law,Bibliometric; Citespace; Emodin; Liver injury; VOSviewer,Emodin/pharmacology; Bibliometrics; Humans; Biomedical Research/trends; Animals,Emodin,Hubei Traditional Chinese Medicine Scientific Research Project (ZY2023Q026); National Natural Science Foundation of China (81974530),,http://dx.doi.org/10.1007/s00210-024-03758-5,39792164,10.1007/s00210-024-03758-5,,,0,000-656-302-827-401; 000-667-231-896-402; 002-052-422-936-00X; 002-162-303-393-820; 003-101-114-396-114; 004-140-385-733-598; 004-159-866-217-228; 005-011-636-083-514; 008-364-297-529-528; 009-443-288-403-343; 012-295-393-765-086; 013-507-404-965-47X; 018-494-873-506-833; 019-606-098-264-756; 019-891-969-858-089; 023-273-531-408-725; 023-706-281-880-920; 028-787-351-085-498; 029-071-453-000-865; 030-288-557-172-808; 033-061-153-523-360; 037-529-473-746-092; 037-905-169-131-460; 039-148-189-973-400; 043-965-539-316-270; 045-574-735-335-182; 047-485-127-231-740; 053-087-218-200-425; 055-105-699-964-491; 056-322-947-136-669; 057-358-380-650-990; 061-011-299-311-969; 064-852-200-624-072; 065-103-186-422-359; 065-807-131-768-809; 067-738-364-907-239; 071-329-024-748-718; 073-341-997-082-232; 077-262-596-223-700; 077-549-676-461-387; 081-072-735-725-290; 089-057-122-829-252; 089-120-652-236-912; 094-861-227-069-921; 098-765-469-639-005; 101-638-474-748-745; 103-636-765-935-675; 104-034-849-578-132; 106-305-117-426-293; 107-890-095-706-783; 109-082-835-439-826; 111-347-371-724-735; 120-852-087-164-447; 121-127-645-006-713; 121-825-311-231-96X; 140-081-152-827-378; 140-230-735-390-610; 141-733-752-929-412; 141-770-516-078-794; 142-581-679-590-657; 145-898-100-676-254; 170-257-920-635-948; 174-517-546-129-466; 176-800-026-142-209; 194-280-018-097-758; 196-430-685-502-458,1,false,, -046-549-017-078-03X,A journey through the conceptual evolution of corporate entrepreneurship and entrepreneurial orientation: a comparative approach,2023-12-07,2023,journal article,International Entrepreneurship and Management Journal,15547191; 15551938,Springer Science and Business Media LLC,Germany,Sara Bermejo-Olivas; Isabel Soriano-Pinar; María-José Pinillos,,20,3,2075,2113,Entrepreneurship; Proactivity; Entrepreneurial orientation; Construct (python library); Phenomenon; Creativity; Order (exchange); Scope (computer science); Knowledge management; Conceptual model; Sociology; Field (mathematics); Marketing; Business; Epistemology; Management; Psychology; Computer science; Economics; Social psychology; Philosophy; Mathematics; Finance; Pure mathematics; Programming language,,,,Universidad Rey Juan Carlos,,http://dx.doi.org/10.1007/s11365-023-00913-x,,10.1007/s11365-023-00913-x,,,0,004-130-251-802-288; 004-819-527-814-707; 010-065-762-504-134; 011-294-098-158-725; 013-507-404-965-47X; 013-524-854-219-241; 014-066-299-958-23X; 014-471-604-683-80X; 015-692-170-714-052; 017-750-600-412-958; 018-996-018-307-518; 020-880-979-562-427; 022-611-268-730-671; 025-216-749-290-709; 027-449-476-127-657; 027-779-480-116-32X; 027-921-836-241-047; 031-871-153-825-563; 033-034-731-916-147; 033-936-535-459-965; 038-167-706-442-702; 038-301-699-616-763; 041-345-698-442-098; 044-151-611-794-538; 048-896-513-299-818; 050-609-067-982-963; 051-647-739-244-271; 054-439-051-844-343; 058-469-304-573-477; 058-489-937-507-355; 058-517-007-035-262; 066-224-475-692-926; 066-301-590-931-132; 066-546-997-546-16X; 075-723-556-019-314; 082-051-865-919-302; 084-587-621-565-040; 086-430-891-731-392; 088-817-042-921-414; 093-470-911-885-138; 098-229-571-559-344; 101-330-410-007-031; 118-469-622-087-655; 122-415-544-444-960; 123-464-593-926-920; 125-856-277-816-370; 126-495-293-862-225; 141-026-656-461-626; 148-507-760-599-870; 150-382-550-909-813; 170-364-942-022-062; 177-882-177-384-49X; 179-989-504-243-575,5,false,, -046-613-696-713-616,Research trend and dynamical development of focusing on the global critical metals: a bibliometric analysis during 1991-2020.,2021-12-02,2021,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Wei Liu; Xin Li; Minxi Wang; Litao Liu,,29,18,1,18,Climate change; Regional science; Political science; Bibliometrics; Metal flow; Bibliometric analysis; Multiple time dimensions; Global environmental analysis; Process (engineering),Bibliometric analysis; Critical metals; Precious metals; Rare metals,Bibliometrics; Climate Change; Forecasting; Publications; Universities,,the national natural science foundation of china (71991484); the national natural science foundation of china (71991481),https://link.springer.com/article/10.1007/s11356-021-17816-5,http://dx.doi.org/10.1007/s11356-021-17816-5,34855179,10.1007/s11356-021-17816-5,3215728469,,0,000-689-955-931-653; 000-826-392-662-573; 001-125-894-837-518; 001-845-845-744-994; 002-052-422-936-00X; 002-784-631-807-793; 003-520-918-144-111; 005-357-140-056-289; 010-442-924-794-711; 012-324-230-731-770; 012-666-059-881-68X; 013-507-404-965-47X; 014-089-305-730-98X; 015-195-632-581-868; 018-480-032-761-795; 020-027-320-743-459; 020-080-046-935-409; 022-833-871-741-926; 025-669-652-322-577; 026-579-008-077-248; 026-767-781-638-012; 027-885-666-103-059; 029-558-080-212-156; 029-924-135-452-059; 029-953-034-291-762; 032-718-430-518-699; 033-654-720-762-530; 035-187-339-680-643; 037-133-395-545-306; 037-937-289-595-557; 039-758-466-924-139; 042-145-461-170-696; 042-321-825-811-440; 043-666-095-511-277; 044-089-355-742-952; 044-500-926-502-969; 044-922-307-250-416; 045-554-623-319-489; 046-358-094-699-962; 047-784-432-046-832; 049-001-232-202-553; 051-292-164-193-468; 052-692-372-125-59X; 053-345-403-562-187; 060-871-143-567-195; 061-265-495-851-743; 063-002-982-772-901; 066-327-011-101-288; 066-527-920-751-663; 069-511-868-544-95X; 070-665-150-453-490; 071-339-115-676-886; 071-878-836-294-733; 071-989-502-705-725; 072-895-096-586-255; 074-555-462-118-331; 075-116-385-297-525; 077-944-981-828-886; 078-362-133-960-637; 083-054-885-298-03X; 083-349-011-468-163; 086-276-683-712-696; 087-295-497-286-881; 096-626-189-653-205; 097-796-194-250-839; 101-353-880-163-284; 101-511-885-337-467; 108-617-730-683-63X; 110-968-925-031-806; 116-509-540-826-662; 118-396-014-121-683; 126-136-869-921-458; 136-499-951-948-938; 139-649-663-651-283; 146-508-029-841-762; 150-999-199-892-857; 155-609-455-863-517; 163-505-822-344-545; 164-441-706-689-163; 176-203-588-918-894,13,false,, -046-723-749-451-478,"Visualization and Analysis of Hotspots and Trends in Seafood Cold Chain Logistics Based on CiteSpace, VOSviewer, and RStudio Bibliometrix",2024-07-30,2024,journal article,Sustainability,20711050,MDPI AG,Switzerland,Lin Hu; Qinghai Chen; Tingting Yang; Chuanjian Yi; Jing Chen,"The development of cold chain logistics for seafood plays a pivotal role in guaranteeing food safety, promoting economic progress, reducing losses, and fostering sustainable development, thereby enhancing the overall efficiency of the seafood supply chain. This study conducted a comprehensive investigation into the primary research focuses of the seafood cold chain logistics field using the literature on visualization analysis software (CiteSpace (6.2.R6), VOSviewer (1.6.20), and RStudio Bibliometrix (4.4.0)). A total of 1787 articles were collected and further analyzed from the China National Knowledge Infrastructure (CNKI), Web of Science (WOS), and Google databases over 12 years, establishing a knowledge framework for research in seafood cold chain logistics. Through the utilization of keyword clustering and emerging analysis techniques, the study constructed a knowledge map that intuitively describes the emerging trends and key hotspot in this field. The results indicate a growing trend in the seafood cold chain logistics field, with disciplines such as mathematics, systems, and physics being notably prominent. Key terms such as “cold chain logistics”, “highlighted supply chain management”, “frozen storage techniques”, “cold storage practices”, “post-harvest loss prevention strategies”, and “optimization of the cold chain” frequently appear in the literature, highlighting the importance of interdisciplinary academic research in these areas. By exploring the current development of the seafood cold chain logistics field, we strengthen the research gaps in the literature and propose future research directions. Therefore, well-conducted bibliometric studies can play a crucial role in advancing the field by providing comprehensive insights, facilitating scholarly discussions, identifying knowledge gaps, generating new research ideas, and showcasing their intended contributions to the field.",16,15,6502,6502,Visualization; Cold chain; Business; Geography; Economic geography; Computer science; Engineering; Mechanical engineering; Data mining,,,,Zhejiang Province Basic Research Project of Provincial Colleges and Universities,,http://dx.doi.org/10.3390/su16156502,,10.3390/su16156502,,,0,000-525-157-502-132; 002-052-422-936-00X; 004-050-840-001-024; 005-588-363-310-297; 007-016-826-558-870; 007-737-085-058-253; 010-547-438-975-817; 011-188-848-769-498; 011-301-822-302-672; 012-533-806-315-472; 013-261-296-086-031; 013-772-772-516-480; 016-086-627-266-47X; 016-954-218-318-07X; 017-750-600-412-958; 021-444-289-998-843; 021-558-443-408-051; 021-672-151-028-435; 022-523-997-153-296; 023-641-126-987-950; 025-547-925-453-674; 028-990-820-695-461; 033-706-469-387-401; 034-042-618-086-993; 036-108-809-004-112; 036-199-236-064-359; 044-354-597-287-934; 046-590-890-568-150; 046-992-864-415-70X; 047-134-478-431-993; 048-761-843-916-657; 048-864-396-576-743; 049-500-785-238-720; 050-053-442-536-172; 053-311-448-166-668; 054-902-630-891-322; 058-675-831-939-968; 063-191-107-307-898; 064-400-499-357-900; 066-712-125-190-144; 066-832-909-756-501; 067-467-480-908-624; 068-123-110-870-523; 070-769-315-064-044; 073-775-823-470-313; 081-612-542-031-262; 084-650-147-783-727; 084-692-085-535-036; 086-216-549-776-184; 086-657-899-224-519; 088-371-546-047-042; 090-764-112-453-771; 091-891-734-697-576; 118-643-589-892-855; 122-982-610-269-98X; 123-930-404-572-031; 138-991-403-049-285; 142-796-471-855-044; 145-057-103-628-382; 145-404-929-838-486; 146-609-751-973-810; 158-873-273-790-945; 159-470-911-400-471; 164-855-055-820-905; 176-743-360-057-845,5,true,,gold -047-000-413-205-449,Analisis bibliometrik: Penelitian technology acceptance model tahun 2014-2023 menggunakan Bibliometrik dan Vosviewer,2024-12-30,2024,journal article,Comdent: Communication Student Journal,29868297,Universitas Padjadjaran,,Naufal Mufadhdhal Hidayatullah; Bibo Bani; Calista Angelia; Hilda Nurhidayati; Siska Agus Rini Ningrum,"Latar Belakang: Dalam era digital yang terus berkembang, teknologi semakin menjadi elemen penting dalam berbagai aspek kehidupan, termasuk di sektor bisnis, pendidikan, kesehatan, dan interaksi sosial. Salah satu teori yang banyak digunakan untuk memahami penerimaan teknologi informasi adalah Technology Acceptance Model (TAM), yang diperkenalkan oleh Davis pada tahun 1989. Model ini menekankan dua faktor utama yang memengaruhi keputusan individu untuk mengadopsi teknologi, yaitu perceived ease of use (kemudahan penggunaan yang dirasakan) dan perceived usefulness (manfaat yang dirasakan). Kedua elemen ini memainkan peran krusial dalam menentukan niat pengguna untuk menerima dan menggunakan teknologi baru. Tujuan: Dengan menggunakan analisis visual dari Bibliometrix, studi ini menyajikan tinjauan mendalam mengenai berbagai aspek penelitian yang berkaitan dengan model TAM. Ini mencakup tren penelitian yang muncul, identitas penulis dan institusi yang berkontribusi, artikel yang paling banyak disitasi, serta jaringan kata kunci dari berbagai negara. Metode: Penelitian ini mengadopsi metode analisis bibliometrik dengan memanfaatkan perangkat lunak Bibliometrix dan VOSviewer untuk meneliti publikasi terkait model TAM. Data yang digunakan diambil dari basis data Scopus dalam rentang waktu antara tahun 2014 hingga 2023. Hasil: Hasil penelitian memberikan gambaran komprehensif dan sistematis tentang evolusi dan karakteristik penerapan TAM. Dengan pemahaman yang lebih mendalam mengenai faktor-faktor yang memengaruhi penerimaan teknologi, penelitian ini diharapkan dapat menjadi referensi berharga bagi akademisi dan praktisi yang tertarik dalam bidang teknologi informasi dan adopsi teknologi, serta mendukung pengembangan strategi yang lebih efektif untuk meningkatkan penggunaan teknologi dalam masyarakat.",2,1,138,158,Technology acceptance model; Computer science; Operating system; Usability,,,,,,http://dx.doi.org/10.24198/comdent.v2i1.58290,,10.24198/comdent.v2i1.58290,,,0,,1,false,, -047-095-352-438-031,A Systematic Review and Characterization of the Major and Most Studied Urban Soil Threats in the European Union,2024-07-04,2024,journal article,"Water, Air, & Soil Pollution",00496979; 15732932,Springer Science and Business Media LLC,Netherlands,Hannah Binner; Piotr Wojda; Felipe Yunta; Timo Breure; Andrea Schievano; Emanuele Massaro; Arwyn Jones; Jennifer Newell; Remigio Paradelo; Iustina Popescu Boajă; Edita Baltrėnaitė-Gedienė; Teresa Tuttolomondo; Nicolò Iacuzzi; Giulia Bondi; Vesna Zupanc; Laure Mamy; Lorenza Pacini; Mauro De Feudis; Valeria Cardelli; Alicja Kicińska; Michael J. Stock; Hongdou Liu; Erdona Demiraj; Calogero Schillaci,"AbstractThere is an urgent need by the European Union to establish baseline levels for many widespread pollutants and to set out specific levels for these under the Zero pollution action plan. To date, few systematic reviews, superseded by bibliometric analyses, have explored this issue. Even less research has been carried out to compare the efficacy of these two data extraction approaches. This study aims to address these two issues by i) constructing an inventory of the available information on urban soils, highlighting evidence gaps and measuring compliance with the Zero pollution action plan, and by ii) comparing the methods and results of these two data extraction approaches. Through Scopus and Web of Science databases, peer-reviewed articles using the terms urban soil in combination with specific urban soil threats and/or challenges were included. Notably, both approaches retrieved a similar number of initial articles overall, while the bibliometric analysis removed fewer duplicates and excluded fewer articles overall, leaving the total number of articles included in each approach as: 603 articles in the systematic review and 2372 articles in the bibliometric analysis. Nevertheless, both approaches identified the two main urban soil threats and/or challenges to be linked to soil organic carbon and/or heavy metals. This study gives timely input into the Zero pollution action plan and makes recommendations to stakeholders within the urban context.",235,8,,,Action plan; Context (archaeology); European union; Environmental planning; Systematic review; Plan (archaeology); Environmental science; Geography; Political science; Business; MEDLINE; Ecology; Archaeology; Economic policy; Law; Biology,,,,,https://hal.inrae.fr/hal-04664756/document https://hal.inrae.fr/hal-04664756,http://dx.doi.org/10.1007/s11270-024-07288-x,,10.1007/s11270-024-07288-x,,,0,002-234-062-357-887; 003-356-746-164-818; 008-630-952-641-452; 008-962-921-400-817; 013-507-404-965-47X; 015-249-717-926-491; 016-712-869-096-157; 016-993-830-128-493; 017-869-403-005-294; 019-536-680-311-06X; 021-574-075-396-244; 022-219-730-852-649; 022-649-817-138-86X; 025-534-564-931-075; 029-119-056-332-540; 029-436-507-268-082; 029-551-977-730-490; 032-253-156-010-333; 032-795-101-321-931; 032-842-595-735-876; 033-766-081-662-221; 033-772-254-334-56X; 035-926-278-379-190; 045-422-273-148-899; 054-393-509-411-11X; 056-902-731-346-836; 061-284-756-062-018; 061-568-456-953-956; 064-436-733-082-98X; 064-682-714-743-301; 070-594-305-686-219; 073-187-792-563-005; 073-836-206-051-662; 083-663-132-005-419; 088-974-369-757-248; 096-508-069-108-627; 099-365-275-613-556; 100-731-254-997-803; 103-170-781-601-112; 108-759-894-055-780; 115-377-326-767-78X; 118-017-644-908-699; 139-548-851-774-122; 142-143-906-981-755; 149-272-363-000-791; 151-544-481-137-252; 153-886-294-142-358; 154-940-135-260-390; 155-836-165-826-005; 159-878-380-189-775; 170-706-022-042-48X; 170-885-929-088-626; 176-853-121-877-851; 183-436-199-207-627; 198-428-619-005-111; 199-223-492-994-772,1,true,cc-by,hybrid -047-176-587-567-449,Unveiling the Immune effects of AHR in tumors: a decade of insights from bibliometric analysis (2010-2023).,2024-11-04,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Anni Xie; Ting Wang; Wenjing Shi; Fang He; Xin Sun; Ping Li,"The Aryl Hydrocarbon Receptor (AHR) is a transcription factor that regulates several biological processes. Its potential in anti-tumor immunotherapy is becoming clearer, yet no bibliometric studies on this topic exist. This study aims to understand the current research landscape and identify future directions through a bibliometric analysis of AHR's anti-tumor immunological effects.; We conducted a comprehensive bibliometric analysis of AHR antitumor immunotherapy papers in the Web of Science Core Collection. Various aspects of the publications were analyzed, and research hotspots and future trends were identified using scientific bibliometric tools and statistical methods.; We collected 592 English papers published between 2010 and 2023, with an almost annual increase. Most publications were from the USA, followed by China, Germany, and Italy. The journal ""Frontiers in Immunology"" had the most papers, and the most cited paper was Christiane A. Opitz's ""An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor."" The research is centered around AHR gene expression, with a growing focus on intestinal disease and the development of Programmed cell death ligand 1 (PD-L1) drugs.; This bibliometric study highlights the significance of AHR in immunomodulatory research, outlining the research trends and key contributors. It suggests AHR's immune effects may mediate the process of colitis cancer transformation, providing valuable insights for future anti-tumor immunotherapy strategies based on AHR.; © 2024. The Author(s).",15,1,616,,Immune system; Computational biology; Medicine; Biology; Immunology,AHR; Cancer; Immunotherapy; Intestinal diseases; Selective AHR modulators,,,National famous old Chinese medicine experts inheritance studio construction project (Anhui Traditional Chinese Medicine Development Secret [2022] No. 19); Anhui Provincial Key Research and Development Project (No：106155447007),,http://dx.doi.org/10.1007/s12672-024-01480-5,39495340,10.1007/s12672-024-01480-5,,PMC11535112,0,002-204-659-351-325; 002-343-435-270-403; 003-412-824-658-543; 003-962-702-957-55X; 005-654-600-727-233; 006-476-955-037-896; 007-498-347-713-161; 008-721-650-540-553; 009-233-786-437-049; 011-845-624-351-487; 012-072-753-499-036; 012-635-668-798-96X; 012-822-063-009-837; 016-304-484-764-721; 018-848-970-610-240; 020-559-848-341-367; 020-610-186-565-855; 025-300-942-347-051; 029-271-117-864-02X; 032-089-041-698-711; 033-560-124-136-587; 034-948-896-903-982; 035-524-739-632-282; 035-955-580-701-550; 038-624-506-232-445; 040-907-108-971-80X; 042-812-283-741-818; 048-784-846-909-972; 049-060-759-919-999; 051-344-360-884-188; 053-573-518-190-066; 062-231-343-563-719; 063-465-167-316-847; 064-779-020-870-278; 065-070-275-674-250; 066-920-236-482-277; 070-051-249-471-801; 070-309-944-099-875; 070-490-815-965-588; 072-649-430-703-266; 074-427-987-291-069; 076-590-944-573-456; 078-744-412-814-396; 080-744-757-026-098; 082-952-176-432-177; 083-996-770-816-895; 084-037-085-032-85X; 090-100-268-286-381; 091-365-905-389-894; 093-240-801-429-189; 094-823-250-228-487; 103-143-885-108-521; 109-988-027-379-205; 118-901-995-042-02X; 133-758-422-993-076; 137-101-736-066-653; 141-770-516-078-794; 151-109-838-176-048; 157-217-087-845-250; 162-090-529-383-096; 170-076-815-205-900; 174-157-656-262-966; 192-963-881-091-63X; 196-995-565-663-546,0,true,cc-by,gold -047-398-318-565-115,Comprehensive Science Mapping Analysis [R package bibliometrix version 3.0.3],2020-09-28,2020,,,,,,Massimo Aria; Corrado Cuccurullo,,,,,,Programming language; R package; Science mapping; Computer science,,,,,https://cran.uni-muenster.de/web/packages/bibliometrix/index.html,https://cran.uni-muenster.de/web/packages/bibliometrix/index.html,,,3088069277,,0,,2,false,, -047-659-701-786-060,Hotspots and Trends of Layered Double Hydroxide-based Adsorbents for Polluted Water Treatment: Insights from Bibliometric Analysis.,2022-12-20,2022,journal article,Environmental management,14321009; 0364152x,Springer Science and Business Media LLC,Germany,Juliana Cristina Pereira Lima Paulino; Anamália Ferreira da Silva; Danilo Henrique da Silva Santos; Patrícia de Carvalho Nagliate; Lucas Meili,,71,5,1098,1109,Context (archaeology); Hazardous waste; China; Relevance (law); Environmental engineering science; Web of science; Layered double hydroxides; Biogeosciences; Computer science; Environmental science; Hydroxide; Engineering; Earth science; Geography; Waste management; Chemical engineering; Geology; Chemistry; Political science; Archaeology; MEDLINE; Law; Biochemistry,Adsorption; Clays; Review; Water pollution,Hydroxides/chemistry; Bibliometrics; Environmental Pollutants; Water Purification/methods,hydroxide ion; Hydroxides; Environmental Pollutants,,https://www.researchsquare.com/article/rs-2070633/latest.pdf https://doi.org/10.21203/rs.3.rs-2070633/v1,http://dx.doi.org/10.1007/s00267-022-01770-0,36539637,10.1007/s00267-022-01770-0,,,0,000-381-106-798-244; 002-418-123-136-567; 009-269-971-248-463; 012-523-603-592-083; 018-717-128-288-309; 019-951-927-463-769; 025-861-858-994-600; 026-327-059-877-391; 028-500-395-012-492; 030-145-143-088-894; 031-621-194-919-96X; 035-365-497-945-36X; 035-607-958-455-304; 035-708-728-048-810; 037-745-654-197-439; 047-134-478-431-993; 047-248-371-509-995; 048-858-915-889-899; 050-459-670-212-727; 051-666-244-422-877; 053-326-407-152-712; 057-831-118-803-657; 058-129-144-774-032; 060-110-039-971-60X; 061-750-598-722-847; 068-627-915-760-742; 076-028-630-451-861; 079-679-789-158-219; 081-178-436-329-306; 081-752-587-278-538; 093-311-528-815-737; 100-426-722-027-963; 104-402-413-215-716; 114-838-421-876-557; 117-211-320-748-409; 143-525-108-687-56X; 151-374-017-201-602; 166-124-752-126-154; 184-852-020-939-633,0,false,, -047-927-775-987-226,A 2-decade bibliometric analysis of epigenetics of cardiovascular disease: from past to present.,2023-11-25,2023,journal article,Clinical epigenetics,18687083; 18687075,Springer Science and Business Media LLC,Germany,Yukang Mao; Kun Zhao; Nannan Chen; Qiangqiang Fu; Yimeng Zhou; Chuiyu Kong; Peng Li; Chuanxi Yang,"Cardiovascular disease (CVD) remains a major health killer worldwide, and the role of epigenetic regulation in CVD has been widely studied in recent decades. Herein, we perform a bibliometric study to decipher how research topics in this field have evolved during the past 2 decades.; Publications on epigenetics in CVD produced during the period 2000-2022 were retrieved from the Web of Science Core Collection (WoSCC). We utilized Bibliometrix to build a science map of the publications and applied VOSviewer and CiteSpace to assess co-authorship, co-citation, co-occurrence, and bibliographic coupling. In total, 27,762 publications were included for bibliometric analysis. The yearly amount of publications experienced exponential growth. The top 3 most influential countries were China, the United States, and Germany, while the most cited institutions were Nanjing Medical University, Harbin Medical University, and Shanghai Jiao Tong University. Four major research trends were identified: (a) epigenetic mechanisms of CVD; (b) epigenetics-based therapies for CVD; (c) epigenetic profiles of specific CVDs; and (d) epigenetic biomarkers for CVD diagnosis/prediction. The latest and most important research topics, including ""nlrp3 inflammasome"", ""myocardial injury"", and ""reperfusion injury"", were determined by detecting citation bursts of co-occurring keywords. The most cited reference was a review of the current knowledge about how miRNAs recognize target genes and modulate their expression and function.; The number and impact of global publications on epigenetics in CVD have expanded rapidly over time. Our findings may provide insights into the epigenetic basis of CVD pathogenesis, diagnosis, and treatment.; © 2023. The Author(s).",15,1,184,,Epigenetics; Disease; Medicine; Bibliometrics; Bioinformatics; Data science; Biology; Library science; Pathology; Genetics; Computer science; Gene,Bibliometric; Bibliometric study; Cardiovascular disease; CiteSpace; Epigenetics; VOSviewer; Visualization,"Humans; Cardiovascular Diseases/genetics; Epigenesis, Genetic; China; DNA Methylation; Bibliometrics",,The Youth Program of the National Natural Science Foundation of China (82300311); The Academy talent special fund of The First Affiliated Hospital of Nanjing Medical University (YNRCQN0312); the Youth Program of the National Natural Science Foundation of China (82200379),https://clinicalepigeneticsjournal.biomedcentral.com/counter/pdf/10.1186/s13148-023-01603-9 https://doi.org/10.1186/s13148-023-01603-9,http://dx.doi.org/10.1186/s13148-023-01603-9,38007493,10.1186/s13148-023-01603-9,,PMC10676610,0,000-952-110-971-261; 002-052-422-936-00X; 002-918-941-898-329; 005-290-789-394-027; 005-324-225-820-134; 005-639-686-100-46X; 005-831-816-190-767; 005-956-590-290-130; 006-705-393-080-679; 008-400-646-040-866; 013-507-404-965-47X; 014-041-705-287-435; 015-242-168-041-874; 019-706-336-089-489; 020-588-347-235-737; 021-005-335-641-964; 021-424-077-517-747; 023-140-418-952-658; 023-841-019-437-52X; 023-927-221-065-800; 025-780-501-443-596; 026-290-282-894-93X; 026-395-112-558-483; 027-164-423-485-427; 030-093-915-685-84X; 031-908-555-455-856; 033-265-386-712-722; 034-142-848-712-046; 037-318-344-990-347; 038-997-092-842-711; 039-564-743-879-984; 045-422-273-148-899; 046-328-695-398-850; 046-992-864-415-70X; 047-762-563-055-889; 050-058-879-780-998; 050-351-991-217-372; 052-256-868-209-892; 053-390-787-921-136; 054-818-565-070-154; 057-124-103-401-53X; 057-192-328-739-034; 063-217-223-682-962; 065-451-446-115-699; 073-240-057-512-869; 078-714-801-104-681; 081-418-092-085-052; 082-676-138-271-984; 087-790-908-527-992; 090-731-522-534-055; 091-905-038-504-958; 092-328-357-527-427; 094-159-592-916-885; 098-367-848-560-678; 105-019-584-427-806; 106-945-295-200-575; 108-051-135-736-928; 115-482-217-358-287; 123-803-257-318-612; 137-515-453-896-833; 137-763-030-823-395; 140-188-845-069-311; 141-334-772-840-329; 148-317-944-577-425; 157-924-768-038-350; 173-515-980-602-484; 193-936-715-241-05X,10,true,"CC BY, CC0",gold -048-051-717-191-548,Synthesis on ESG performance and green innovation Based on Quantitative Methods-Bibliometrix R Package,2023-09-28,2023,book chapter,Atlantis Highlights in Computer Sciences,27317900; 25894900,Atlantis Press International BV,,Jiaxin Zhang,"In the context of UN Sustainable Develop Goals of 2030, the ESG performance and green innovation is an attracting field for not only scholars, but also managerial and governors.Yet few scholars have made contribution on synthesizing knowledges of this field.With assisting of R package Bibliometrix, this research employs mathematical method, which is the bibliometric analysis, to help give an insight of ESG performance and green innovation.Bibliometrics is the use of statistical analysis and quantitative methods to measure and analyze information within publications.It helps assess the impact, evaluate productivity, and understand trends in research and scholarly communication.A total of 77 articles were retrieved from WoS core collection.The results are visually represented as well as prosperous future research topics for academics diving into.The ESG performance and green innovation is currently in bursting stage.Ownership, financial constraints, incentives, sustainability, performance management, and economic growth is the motor theme, worthing dig into.The results may help scholars quickly understand this field and identify frontier.In addition, this research also provided a value reference for conducting bibliographic analysis in ESG performance and green innovation field as well as other scholar domains.",,,404,409,Business,,,,,https://www.atlantis-press.com/article/125991658.pdf https://doi.org/10.2991/978-94-6463-264-4_45,http://dx.doi.org/10.2991/978-94-6463-264-4_45,,10.2991/978-94-6463-264-4_45,,,0,,0,true,cc-by-nc,hybrid -048-222-332-963-635,AUTOENCODER VARIACIONAL COMOTÉCNICA DE BALANCEAMENTO DE BANCO DE DADOS DE ÁUDIOS RESPIRATÓRIOS,,2022,journal article,Revista SODEBRAS,18093957,Revista SODEBRAS,,"V. M. Casas; D. A. Chen; J. P. C. Mendes; M. P, Bastos; V. V. Valenzuela; C. A. M. Nepomuceno","The professional nurse, when dealing with a patient, often experiences adverse situations in their work environment. This can affect their health. In order to know about this daily life, the present study aimed to carry out a bibliometric analysis on the theme Burnout in nurses where, in a more punctual way, we sought to identify the main predictors of Burnout of this profession from recent international publications. In the first part of the study, the software R (bibliometrix package) was used. Burnout predictors were identified from the articles resulting from the bibliometric search. The survey results pointed to an increase in publications over the years with a peak in 2018. The largest contributions in quantitative terms are still from the United States of America. Burnout predictors have an organizational and relational origin. Individual aspects, such as resilience, appear in a relevant way to avoid professional illness.",17,197,19,30,Autoencoder; Environmental science; Computer science; Artificial neural network; Artificial intelligence,,,,,,http://dx.doi.org/10.29367/issn.1809-3957.17.2022.197.19,,10.29367/issn.1809-3957.17.2022.197.19,,,0,,0,true,,gold -048-411-766-230-204,"Mobile health applications for health-care delivery: trends, opportunities, and challenges",2023-12-13,2023,journal article,Journal of Public Health,21981833; 16132238; 09431853,Springer Science and Business Media LLC,Germany,Anushka Goel; Udita Taneja,,,,,,Thematic analysis; Health care; Health technology; Knowledge management; Psychological intervention; Data science; Business; Public relations; Medicine; Computer science; Political science; Qualitative research; Sociology; Nursing; Social science; Law,,,,,,http://dx.doi.org/10.1007/s10389-023-02165-z,,10.1007/s10389-023-02165-z,,,0,002-096-990-063-82X; 002-252-973-501-228; 004-395-194-434-274; 005-451-130-728-580; 005-563-950-302-610; 006-193-546-720-651; 011-643-570-685-602; 012-428-367-365-536; 012-537-069-639-001; 013-007-451-898-897; 015-902-749-741-618; 017-915-000-594-631; 018-439-946-902-473; 020-788-955-410-371; 021-240-080-971-768; 022-301-403-548-706; 030-548-860-345-511; 031-034-847-547-811; 031-745-948-147-404; 032-061-464-112-335; 033-647-970-686-088; 034-911-545-939-458; 035-852-262-941-645; 037-022-775-806-107; 041-127-178-792-70X; 042-104-084-138-533; 043-468-504-675-233; 046-579-624-360-405; 049-370-620-573-851; 049-954-029-977-583; 050-609-067-982-963; 052-478-868-614-787; 054-219-516-647-67X; 064-294-164-731-597; 065-003-321-174-397; 069-407-183-448-172; 078-549-659-378-318; 078-582-680-636-961; 078-918-547-868-970; 088-589-063-696-437; 101-696-297-484-763; 101-767-856-072-200; 112-170-501-693-021; 117-191-203-399-013; 119-397-967-338-890; 121-813-144-996-86X; 123-285-967-267-306; 142-693-927-846-524; 155-063-805-018-38X; 160-671-580-903-387; 168-518-309-992-925,5,false,, -048-522-829-495-667,Bibliometric insights into mobile money and data trends.,2025-05-08,2025,journal article,Data in brief,23523409,Elsevier BV,Netherlands,Thi Thuy Hang Vu,"This data aims to analyze the intellectual structure of mobile money studies by examining bibliographic characteristics. A dataset of 165 documents from the Scopus database was used. This study explored various aspects, including annual publication counts, country coupling, source numbers, primary research areas, co-occurrence of keywords, bibliographic linkages between sources and documents, and co-citation patterns of references. Bibliographic network mapping techniques were applied to analyze the data. The analysis was performed using VOSviewer and the Bibliometrix R package, software tools for scientific mapping. The results showed four main themes of the mobile money dataset: mobile money in Africa, financial inclusion, electronic money, and digital financial services.",60,,111633,111633,Data science; Bibliometrics; Computer science; World Wide Web,Bibliometric analysis; Bibliometrix R package; Data trends; Mobile money; VOSviewer,,,,,http://dx.doi.org/10.1016/j.dib.2025.111633,40486241,10.1016/j.dib.2025.111633,,PMC12145542,0,011-012-493-485-525; 015-189-513-637-602; 019-431-676-028-615; 030-982-983-873-092; 032-047-495-021-419; 041-725-701-442-828; 050-083-854-809-226; 072-106-836-514-253; 084-292-319-255-051; 097-016-099-841-913; 112-095-463-795-512; 126-905-595-567-407; 128-743-728-102-675; 141-128-206-230-414; 162-475-625-866-730; 169-597-482-704-928; 179-939-494-702-292; 183-193-765-956-750,0,true,cc-by,gold -048-596-257-601-218,Mapping the intellectual structure of GIS-T field (2008–2019): a dynamic co-word analysis,2021-02-19,2021,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Seyedmohammadreza Hosseini; Hamed Baziyad; Rasoul Norouzi; Sheida Jabbedari Khiabani; Győző Gidófalvi; Amir Albadvi; Abbas Alimohammadi; Seyedehsan Seyedabrishami,"Using geographic information systems (GIS) widely for dealing with transportation problems (is well-known as GIS-T), has made it nessasary for researchers to discover the current state-of-the-art and predict the trends of future research. This paper aims to contribute to a better understanding of GIS-T research area from a longitudinal perspective, over the period 2008–2019. A co-word analysis was used to illustrate all the underlying subfields of GIS-T based on published papers in the Web of Science (WoS) database service. The main knowledge areas representing the intellectual structure of GIS-T including (a) sustainability, (b) health, (c) planning and management, and (d) methods and tools, were detected. Finally, in order to illustrate the structure and development of the identified clusters, two-dimensional maps and strategic diagrams for each period were drawn. This study is the first attempt to employ a text mining method so as to detect the conceptual structure of GIS-T research area from a complex and interdisciplinary literature.",126,4,2667,2688,Perspective (geometry); Field (geography); Structure (mathematical logic); Data science; Period (music); Service (systems architecture); Computer science; Geographic information system; Word (computer architecture); Sustainability,,,,Royal Institute of Technology,https://link.springer.com/10.1007/s11192-020-03840-8 https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics126.html#HosseiniBNKGAAS21 https://ideas.repec.org/a/spr/scient/v126y2021i4d10.1007_s11192-020-03840-8.html https://link.springer.com/content/pdf/10.1007/s11192-020-03840-8.pdf https://link.springer.com/article/10.1007/s11192-020-03840-8 https://doi.org/10.1007/s11192-020-03840-8 https://www.scilit.net/article/6afe5e2bbb3d78a25a7ad1bdf618d185,http://dx.doi.org/10.1007/s11192-020-03840-8,,10.1007/s11192-020-03840-8,3133429097,,0,000-357-024-107-673; 001-866-915-699-213; 002-052-422-936-00X; 003-274-171-935-140; 004-104-644-806-918; 004-819-527-814-707; 006-461-237-333-939; 006-896-176-363-239; 008-317-443-074-989; 008-694-480-503-432; 011-792-082-731-55X; 013-507-404-965-47X; 013-604-532-354-205; 014-727-582-122-88X; 022-216-189-843-184; 027-242-279-558-863; 030-636-989-152-614; 032-960-136-494-812; 034-565-665-655-178; 035-321-125-346-708; 036-554-675-857-864; 039-195-177-217-458; 040-217-584-255-857; 043-569-104-773-734; 046-811-072-264-039; 048-040-392-733-009; 049-391-379-302-694; 051-647-739-244-271; 052-307-353-403-693; 053-598-695-896-482; 053-786-467-071-25X; 054-752-193-301-257; 058-029-140-081-708; 058-654-569-334-476; 060-110-039-971-60X; 062-445-809-817-439; 064-400-499-357-900; 066-493-430-108-680; 069-146-006-064-335; 070-991-282-066-330; 082-142-826-890-90X; 084-810-957-995-502; 084-832-502-830-354; 085-394-648-196-543; 086-038-890-333-134; 086-293-048-914-007; 090-125-770-085-551; 090-706-232-527-709; 093-218-840-885-661; 102-093-536-537-361; 108-167-347-262-992; 110-339-725-499-883; 111-303-494-331-70X; 123-028-276-947-663; 127-861-322-764-928; 128-530-615-512-249; 129-414-633-906-901; 138-561-175-358-392; 141-200-607-894-303; 160-251-934-148-980; 168-421-516-625-350; 173-903-632-033-021; 176-613-431-700-098; 194-487-631-682-136,30,true,cc-by,hybrid -048-811-834-245-276,Pedagogical innovation in the 21st century to improve inclusive educational processes in Latin America,2024-12-30,2024,journal article,Seminars in Medical Writing and Education,30088127,AG Editor (Argentina),,Javier Ramírez-Narváez; Reisner de Jesús Revelo-Méndez; Angela Rodríguez-Rodríguez; Diego Enrique Daluz-Veras,"The aim of this article was to examine the relationship between pedagogical innovation and inclusive education, taking the Latin American region as a starting point; therefore, a qualitative review was carried out with a focus on grounded theory, using Bibliometrix, through RStudio with information extracted from Scopus during the period 2019-2023. The data were processed and analyzed in formats compatible with Excel. The results showed the scientific production on pedagogical innovation in education, the main sources on this topic, the scientific production of the best journals, the most relevant affiliations, scientific production by region and a thematic mapping of key descriptors. It is concluded that higher education institutions and companies headed by governments in Latin America must take advantage of the advancement of technology to encourage individuals to continuously innovate, for the benefit of education and society in general.",3,,593,593,Latin Americans; Political science; Sociology; Mathematics education; Psychology; Law,,,,,,http://dx.doi.org/10.56294/mw2024593,,10.56294/mw2024593,,,0,000-366-885-959-768; 002-031-484-249-632; 002-516-659-106-576; 004-611-365-517-968; 007-054-883-337-094; 010-798-784-679-072; 013-507-404-965-47X; 018-529-036-332-132; 020-112-272-568-970; 023-046-475-886-457; 023-134-042-581-877; 024-294-740-440-704; 024-688-355-473-27X; 026-977-360-286-886; 027-424-529-386-951; 028-113-658-396-097; 028-860-090-081-402; 029-871-596-923-398; 034-961-226-354-423; 037-244-085-619-439; 037-642-783-725-654; 038-086-794-577-820; 038-627-067-548-598; 039-197-370-207-306; 041-146-844-614-096; 042-036-745-407-226; 042-766-636-429-156; 045-306-885-005-604; 049-228-398-677-627; 049-428-873-039-138; 049-979-319-538-635; 050-264-996-189-23X; 051-089-363-338-531; 051-995-132-353-560; 052-100-265-787-422; 053-250-859-635-514; 054-193-600-176-409; 054-616-006-840-065; 055-093-706-085-335; 058-183-558-129-903; 058-427-095-154-122; 058-857-646-871-698; 059-588-221-094-68X; 060-150-040-423-72X; 060-522-825-065-189; 060-537-683-542-673; 061-610-275-715-867; 061-733-296-750-450; 068-249-635-971-435; 071-390-018-510-028; 074-845-704-328-469; 076-004-582-157-564; 076-068-176-494-015; 079-314-600-712-676; 080-462-921-363-18X; 082-118-210-033-862; 082-502-719-596-357; 083-931-510-307-261; 087-494-980-944-858; 088-927-836-830-853; 089-643-912-729-610; 092-197-630-188-482; 094-036-088-950-769; 094-969-204-945-954; 096-035-400-481-054; 098-255-481-619-701; 098-965-220-931-197; 099-091-668-737-757; 099-587-976-364-269; 101-432-137-633-521; 102-224-208-910-910; 104-123-744-630-883; 106-065-286-288-995; 109-439-709-171-805; 111-933-027-721-211; 112-345-979-256-797; 112-359-321-765-752; 113-167-594-459-929; 113-869-015-909-726; 121-813-793-253-88X; 124-799-797-182-899; 124-950-470-782-445; 125-548-059-467-219; 130-572-491-359-736; 132-332-620-941-205; 133-925-793-006-16X; 137-403-775-313-833; 138-012-807-289-515; 138-944-930-978-690; 141-088-269-692-452; 145-619-240-384-806; 151-120-608-035-861; 156-390-192-281-234; 160-834-739-214-166; 162-499-003-708-611; 164-013-283-063-888; 169-618-449-127-356; 170-232-827-454-594; 171-310-390-706-003; 178-391-664-341-673; 179-405-308-668-662; 180-950-138-163-272; 184-747-556-480-993; 186-694-446-713-035; 186-882-636-368-226; 189-411-358-902-537; 194-609-338-353-512; 194-711-602-785-148; 194-882-133-416-978; 198-489-662-924-753; 198-768-278-873-164; 199-201-539-499-369,0,false,, -048-961-621-562-634,Development of energy resilience research landscape using bibliometric analysis,2024-03-12,2024,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Pidpong Janta; Naraphorn Paoprasert; Pichayaluck Patumwongsakorn; Nuwong Chollacoop; Kampanart Silva,,,,,,Resilience (materials science); Environmental resource management; Environmental science; Geography; Physics; Thermodynamics,,,,National Science and Technology Development Agency,,http://dx.doi.org/10.1007/s10668-024-04745-9,,10.1007/s10668-024-04745-9,,,0,001-719-026-803-199; 001-841-235-970-064; 003-875-932-931-069; 007-016-826-558-870; 009-917-321-562-488; 010-495-710-613-419; 013-497-328-534-240; 013-507-404-965-47X; 018-084-767-029-891; 026-229-943-018-628; 030-330-528-637-502; 033-035-527-838-721; 034-275-032-835-085; 035-699-441-979-800; 042-228-490-689-212; 043-131-760-368-351; 043-966-068-330-133; 045-368-114-501-494; 045-422-273-148-899; 046-992-864-415-70X; 049-664-215-795-171; 050-561-610-502-272; 051-993-554-053-673; 052-506-048-091-752; 053-879-938-959-160; 055-222-575-590-371; 055-261-260-539-266; 055-571-734-988-13X; 056-982-754-746-800; 059-583-971-049-930; 061-228-334-274-006; 061-643-215-706-003; 063-952-342-642-892; 065-088-963-343-469; 073-598-449-280-688; 073-760-338-998-200; 079-213-312-367-254; 081-330-301-276-271; 084-225-727-447-001; 088-291-516-888-211; 098-116-249-653-323; 100-991-519-369-820; 103-195-474-409-850; 104-495-326-573-684; 107-759-528-145-237; 111-081-051-959-193; 116-326-062-306-15X; 119-788-177-010-098; 120-514-653-721-833; 122-827-252-276-011; 125-964-115-823-090; 126-198-715-303-677; 128-409-507-244-027; 128-624-867-138-190; 133-564-327-184-822; 140-685-465-562-582; 147-551-009-858-233; 152-080-812-242-318; 153-276-404-358-304; 164-887-511-042-163; 180-376-118-749-838,0,false,, -049-196-686-942-890,Current Overview of Scientific Production Associated with Governance in University: A Bibliometric Analysis,2023-08-02,2023,journal article,HUMAN REVIEW. International Humanities Review / Revista Internacional de Humanidades,26959623,Eurasia Academic Publishing Group,,Edgar German Martínez; Elizabeth Sánchez Vázquez; Fernando Augusto Poveda Aguja; Lugo Manuel Barbosa Guerrero; Edgar Olmedo Cruz Mican,"The main objective of this research is to identify the current panorama of scientific production associated with governance in university institutions. A bibliometric analysis was developed in Scopus using R Core Team 2022-Bibliometrix and Vosviewer software. The results highlight the countries with the highest productivity in the topic of study, with the most representative authors favoring the understanding of governance. The main thematic clusters stand out. It recognizes the role of university governance and its migration to direct spaces and the transition from a face-to-face model.",21,1,37,46,Corporate governance; Scopus; Productivity; Face (sociological concept); Production (economics); Bibliometrics; Panorama; Political science; Knowledge management; Regional science; Library science; Sociology; Management; Computer science; Social science; Economic growth; MEDLINE; Economics; Law; Computer vision; Macroeconomics,,,,,https://journals.eagora.org/revHUMAN/article/download/5028/3310 https://doi.org/10.37467/revhuman.v21.5028,http://dx.doi.org/10.37467/revhuman.v21.5028,,10.37467/revhuman.v21.5028,,,0,002-052-422-936-00X; 013-507-404-965-47X; 036-696-352-616-699; 074-451-013-042-54X; 075-207-977-198-065; 078-997-451-531-36X; 080-045-889-610-939; 097-057-990-480-599; 120-227-368-603-422; 135-751-718-525-918; 151-893-969-019-255; 165-447-911-101-684,1,true,,bronze -049-701-602-141-178,Harnessing the Power of Technology in Statistics Education: A Comprehensive Bibliometric Study,2024-10-07,2024,journal article,Journal of Advanced Research in Applied Sciences and Engineering Technology,24621943,Akademia Baru Publishing,,Edi Irawan; Rizky Rosjanuardi; Sufyani Prabawanto,"This study aims to conduct a bibliometric mapping of research articles on technology in statistics education. The articles under analysis are those published in English-language journals and indexed in the Scopus database. VOSviewer and Bibliometrix software were employed in the data analysis. The search yielded 59 relevant articles published since 1985, with a 1.84% annual growth rate, an average of 11.02 citations per document, and an average document age of 13.7 years. The publications involved 135 authors from 31 countries, with an average of 2.44 co-authors per document. The research findings revealed the formation of five clusters through networking visualization. Based on the thematic map using Bibliometrix, we identified that ""higher education"" and ""R"" are themes that have shown significant development and are crucial for shaping the technology field in statistics education. This bibliometric analysis provides ideas and references for selecting current, potential, and evolving research themes related to technology in statistics education.",58,1,162,180,Power (physics); Statistics; Data science; Computer science; Mathematics; Physics; Quantum mechanics,,,,,,http://dx.doi.org/10.37934/araset.58.1.162180,,10.37934/araset.58.1.162180,,,0,,0,false,, -049-727-736-933-985,Impacts of digital media on children's well-being: A bibliometric analysis,2025-01-01,2025,journal article,Online Journal of Communication and Media Technologies,19863497,Bastas Publications,,Gui Jun; Jiaqing Xu; Mumtaz Aini Alivi; Fan Zhewen; Nasrullah Dharejo; Maria Brony,"The bulk of the literature related to digital media and children exposed various psychologically harmful impacts. This bibliometric analysis is a crucial attempt to document and present existing literature, identify gaps, and recommend further exploring social media’s impact on children’s well-being. The method “the preferred reporting items for systematic reviews and meta-analyses” is employed to investigate the publication on the impacts of digital media on children’s well-being. The data is collected from the Web of Science database, which includes publications published between 2000 and 2023. The final sample consists of 1,037 research publications evaluated using Bibliometrix software. The findings provide insights into how media is a challenge or opportunity for children and their well-being in the modern era. The trends and suggestions in the discussion of digital media’s impacts on children’s well-being are presented in this study.",15,1,e202501,e202501,Social media; Sample (material); Bibliometrics; Web of science; Digital media; Data science; Computer science; Psychology; Meta-analysis; World Wide Web; Medicine; Chemistry; Chromatography; Internal medicine,,,,,,http://dx.doi.org/10.30935/ojcmt/15696,,10.30935/ojcmt/15696,,,0,001-981-401-267-935; 010-442-924-794-711; 010-497-213-243-751; 016-856-876-284-730; 020-080-046-935-409; 033-197-567-546-91X; 044-657-059-116-845; 054-349-230-177-989; 054-982-419-914-085; 056-586-498-588-14X; 059-628-146-121-185; 060-982-215-284-461; 069-830-982-580-151; 075-306-098-503-768; 108-953-238-010-209; 109-680-712-417-627; 118-157-682-560-309; 118-693-792-851-691; 132-308-279-448-387; 137-110-658-343-145; 138-130-850-048-212; 145-364-247-715-901; 156-977-268-839-234; 158-285-703-419-660; 167-148-923-567-724; 177-246-318-269-026,1,false,, -049-927-466-501-635,MANAJEMEN PENGETAHUAN DAN TRANSFORMASI DIGITAL DI ERA INDUSTRI 4.0,2022-05-28,2022,journal article,JURNAL ILMIAH EDUNOMIKA,25981153,STIE AAS Surakarta,,Muhammad Mujtaba Mitra Zuana; Sopiah Sopiah,"This article is an overview of the Systematic Literature Review (SLR) on Knowledge Management (KM), Digital Transformation (DT), and Industry 4.0, which defines the interactions, bonds, and interdependencies of these new research streams. Playing an important role in a progressive discipline, our research summarizes the state of the art past literature using a rigorous methodological approach. The researchers adopted the Scopus database in their analysis and used the Bibliometrix R package. The analysis revealed 761 peer-reviewed English articles. This study shows several research clusters: KM and DT; KM and innovation ecosystem; KM and border technology; and KM, decision making, and Industry 4.0. In addition, this article contributes to identifying growing areas of research that have uncovered previously unknown and interesting relationships between KM, DT, and the public sector. Therefore, the article emphasizes the important role of DT in the development of KM,, discusses future research perspectives as quantitative analysis and combines academics and practitioners.",6,2,,,Scopus; Interdependence; Knowledge management; Political science; Sociology; Computer science; Social science; MEDLINE; Law,,,,,https://jurnal.stie-aas.ac.id/index.php/jie/article/download/5325/pdf https://doi.org/10.29040/jie.v6i2.5325,http://dx.doi.org/10.29040/jie.v6i2.5325,,10.29040/jie.v6i2.5325,,,0,,0,true,,bronze -050-169-041-017-704,La Cultura Tributaria en Colombia,2024-05-30,2024,journal article,Revista Activos,25005278; 01245805,Universidad Santo Tomas,,Campo Elías López-Rodríguez; Ginna Marcela Torres Rodríguez; Vanesa Villarreal Villarreal,"The objective of this research is to characterise the current state of tax culture globally and to identify the development of tax culture in Colombia, in order to conceptually recognise tax culture as a social and economic value of countries. In this regard, a bibliometric analysis was developed from the Scopus database and using the Bibliometrix tool, complemented by a qualitative systematic review using the Prisma protocol. The results of the bibliometric analysis determine that there is a scarce scientific production associated with the topic addressed. Between 2006 and 2021, 53 scientific articles were found globally, finding that the greatest increase in scientific production was generated in 2021; however, from the systematic review of the literature, 8 documents were identified that describe different tools and strategies aimed at promoting tax culture in Colombia. The results of the bibliometric analysis determine that there is a scarce scientific production associated with the topic addressed.  It is concluded that research processes related to tax culture should be strengthened, not only in Colombia but globally.",21,1,72,91,Political science; Humanities; Geography; Philosophy,,,,,https://revistas.usantotomas.edu.co/index.php/activos/article/download/9756/8367 https://doi.org/10.15332/25005278.9756,http://dx.doi.org/10.15332/25005278.9756,,10.15332/25005278.9756,,,0,,1,true,cc-by-nc-sa,gold -050-327-602-052-86X,A bibliometric review on the drivers of environmental migration,2021-03-18,2021,journal article,Ambio,16547209; 00447447,Springer Science and Business Media LLC,Sweden,Chup Priovashini; Bishawjit Mallick,"A large body of literature exists arguing that numerous, complex factors result in environmental migration. Thus, in order to understand environmental migration, we must investigate how its drivers are defined, explained and interrelated. This study aims to produce a comprehensive analysis of the literature on the drivers of environmental migration and assess future opportunities for studying 'environmental migration'. We conduct a systematic literature search using the keywords 'environmental migration' and 'drivers' in Scopus and Web of Knowledge, analysing 146 publications. The findings are organised as a bibliometric analysis, including network analysis and evaluation of publication metrics. Results show that the literature on environmental migration drivers constitutes a relatively new, growing field largely developed in the USA. It is rooted in the wider environmental migration literature and strongly associated with the discourse of climate change impacts as driving factors. Typologies of 'migrants' are more prevalent than 'refugees' when referring to actors.",51,1,1,12,Climate change; Regional science; Refugee; Political science; Bibliometrics; Order (exchange); Driving factors; Web of knowledge; Ecology (disciplines); Scopus,Bibliometrics; Drivers; Environmental migration; Lexical network; Temporal network; VOSViewer,Bibliometrics,,Technische Universität Dresden (F-003661-553-Ü1G-1212042),https://link.springer.com/article/10.1007/s13280-021-01543-9 https://pubmed.ncbi.nlm.nih.gov/33738730/ https://europepmc.org/article/MED/33738730 https://www.ncbi.nlm.nih.gov/pubmed/33738730,http://dx.doi.org/10.1007/s13280-021-01543-9,33738730,10.1007/s13280-021-01543-9,3138742047,PMC8651838,0,000-811-498-474-704; 001-990-082-228-289; 004-758-194-866-27X; 005-375-958-458-435; 007-638-508-642-029; 007-950-280-143-798; 011-660-392-623-058; 011-776-308-473-38X; 013-507-404-965-47X; 014-390-124-422-702; 022-457-733-038-953; 023-089-244-462-788; 025-734-239-790-404; 027-286-754-580-272; 028-560-627-115-867; 029-298-773-304-274; 029-420-167-353-195; 030-687-895-806-920; 031-242-276-474-87X; 033-287-473-265-147; 037-820-060-798-146; 037-990-074-675-94X; 040-837-765-569-780; 044-387-281-434-88X; 045-368-114-501-494; 052-269-012-723-547; 062-969-427-641-930; 064-153-931-330-489; 066-138-303-267-180; 067-298-884-426-635; 076-909-349-031-443; 083-774-868-939-259; 095-609-659-291-050; 098-804-301-113-543; 099-545-582-291-153; 108-071-786-557-665; 109-435-674-872-987; 110-572-425-177-998; 115-245-022-769-407; 119-246-757-816-112; 121-068-147-020-558; 121-631-901-442-921; 122-415-544-444-960; 137-575-523-832-11X; 139-825-694-487-594; 139-901-351-147-055; 140-093-592-152-093; 147-330-789-818-398; 182-103-236-439-32X; 195-156-300-235-403,27,true,,unknown -050-328-799-901-144,Research trend and conceptualization of low-carbon agricultural systems for food security in Brazil and Africa: a systematic and bibliometric analysis,2025-05-30,2025,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Chukwudi Nwaogu; Bridget E. Diagi; W. E. K. P. E. Vremudia Onyeayana; Famous Ozabor; Deborah Omozusi Diagi; Dike Henry Ogbuagu; Modupeola A. O. Chukwudi; Maurício Roberto Cherubin,"Brazilian research institutes have remarkable contributions in promoting food security in Africa through collaborative-knowledge transfer. However, there is lack of information on publications, research production and emerging trends on low-carbon agricultural systems (LoCAS) and food (in)security within and between Brazil and Africa. This work is aimed at mapping the research collaborations, thematic evolution, and publication trends on LoCAS and food security in Brazil and Africa by using a systematic and bibliometric analysis. This is the first time different bibliometric methods (such as VOSviewer, Flourish studio, Bibliometrix and Biblioshiny models in Rstudio) were simultaneously used to investigate the research impacts on LoCAS and food security in the regions. Data were extracted from the Web of Science databases by using the relevant search terms and strings. From the dataset, information relating to LoCAS was extracted and collated from the regions by identifying seven LoCAS and estimated the number of articles reflected on each. A qualified 687 articles, which had annual scientific growth rate of 13.1%, involving 2,839 authors who applied 2,519 keywords and had 10.2% international collaborations was observed. Brazil (22.4%), and South Africa (14.3%) had the highest number of publications. Number of LoCAS increased with corresponding authors countries’ research relevance. Thirty-six core benefits of LoCAS were identified. Authors’ scientific production showed, de Oliveira Silva and Pereira (Brazil), and Thierfelder (Zimbabwe) as the most impactful authors. Published studies reflecting on food (in)security increased by 75% while those for LoCAS increased by 67%. The hybrid bibliometric approach helped to close the knowledge gap on Brazil-African research trajectory on LoCAS and food security, and the roles of countries, authors, institutions, and publishing journals. This knowledge could support in making future agricultural policies to enhance food security, and climate change resilience, especially in Africa where there have been low research and publications on the topic.",6,1,,,,,,,São Paulo Research Foundation; São Paulo Research Foundation,,http://dx.doi.org/10.1007/s43621-025-01071-6,,10.1007/s43621-025-01071-6,,,0,001-462-678-860-462; 001-655-118-733-677; 003-779-152-112-572; 004-958-426-865-193; 005-055-026-765-926; 009-507-428-988-874; 010-721-155-937-504; 011-301-822-302-672; 011-930-613-573-224; 013-507-404-965-47X; 015-119-264-129-311; 015-190-558-834-720; 016-894-278-876-231; 019-136-297-386-285; 020-750-501-347-722; 028-541-513-343-948; 030-350-155-576-476; 031-580-702-394-066; 032-787-410-967-568; 036-221-452-458-641; 036-690-634-170-237; 046-933-222-125-583; 050-211-714-235-041; 058-118-353-354-161; 059-993-608-155-60X; 061-084-635-378-511; 061-437-573-846-789; 063-295-585-323-012; 064-213-777-376-332; 066-743-056-408-702; 066-809-331-195-713; 069-627-795-924-816; 073-300-960-382-118; 076-438-938-315-366; 079-284-396-624-569; 080-333-925-351-855; 083-151-559-971-895; 092-708-995-249-809; 093-708-273-836-565; 096-786-974-963-818; 098-519-743-799-180; 105-873-408-015-995; 106-301-155-320-336; 107-270-866-902-479; 113-375-114-902-642; 114-791-578-625-523; 122-415-544-444-960; 122-583-580-923-216; 131-496-040-613-373; 134-508-023-426-247; 137-908-084-882-15X; 141-011-081-518-879; 142-653-246-700-953; 148-327-576-012-939; 148-338-543-513-343; 149-516-995-423-352; 150-654-365-640-943; 161-562-780-981-746; 161-716-256-121-247; 162-865-686-077-78X; 165-979-048-124-638; 172-369-953-906-053; 178-452-459-845-369,0,true,cc-by,gold -050-732-306-288-447,Smart bibliometrics: an integrated method of science mapping and bibliometric analysis,2022-05-21,2022,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Vilker Zucolotto Pessin; Luciana Harue Yamane; Renato Ribeiro Siman,,127,6,3695,3718,Bibliometrics; Computer science; Dynamism; Data science; Process (computing); The Internet; World Wide Web; Knowledge management; Physics; Quantum mechanics; Operating system,,,,,,http://dx.doi.org/10.1007/s11192-022-04406-6,,10.1007/s11192-022-04406-6,,,0,002-052-422-936-00X; 006-190-345-716-88X; 012-474-050-478-548; 013-507-404-965-47X; 015-726-334-448-292; 019-559-340-184-14X; 022-380-596-265-048; 024-721-950-984-56X; 025-302-119-966-613; 026-012-468-194-501; 033-431-798-149-789; 035-880-669-779-529; 036-317-925-058-530; 037-815-640-424-494; 040-145-312-110-371; 046-992-864-415-70X; 069-488-858-366-501; 081-075-359-153-623; 092-512-273-988-218; 095-258-654-450-233; 101-896-389-538-665; 111-113-605-670-353; 114-679-699-989-067; 120-040-246-058-26X; 130-943-883-626-549; 145-208-161-232-154; 150-446-020-214-870; 170-940-358-363-899,70,false,, -050-769-581-030-829,Trends and hotspots of energy-based imaging in thoracic disease: a bibliometric analysis.,2024-08-14,2024,journal article,Insights into imaging,18694101,Springer Science and Business Media LLC,Germany,Yufan Chen; Ting Wu; Yangtong Zhu; Jiawei Chen; Chen Gao; Linyu Wu,"To conduct a bibliometric analysis of the prospects and obstacles associated with dual- and multi-energy CT in thoracic disease, emphasizing its current standing, advantages, and areas requiring attention.; The Web of Science Core Collection was queried for relevant publications in dual- and multi-energy CT and thoracic applications without a limit on publication date or language. The Bibliometrix packages, VOSviewer, and CiteSpace were used for data analysis. Bibliometric techniques utilized were co-authorship analyses, trend topics, thematic map analyses, thematic evolution analyses, source's production over time, corresponding author's countries, and a treemap of authors' keywords.; A total of 1992 publications and 7200 authors from 313 different sources were examined in this study. The first available document was published in November 1982, and the most cited article was cited 1200 times. Siemens AG in Germany emerged as the most prominent author affiliation, with a total of 221 published articles. The most represented scientific journals were the ""European Radiology"" (181 articles, h-index = 46), followed by the ""European Journal of Radiology"" (148 articles, h-index = 34). Most of the papers were from Germany, the USA, or China. Both the keyword and topic analyses showed the history of dual- and multi-energy CT and the evolution of its application hotspots in the chest.; Our study illustrates the latest advances in dual- and multi-energy CT and its increasingly prominent applications in the chest, especially in lung parenchymal diseases and coronary artery diseases. Photon-counting CT and artificial intelligence will be the emerging hot technologies that continue to develop in the future.; This study aims to provide valuable insights into energy-based imaging in chest disease, validating the clinical application of multi-energy CT together with photon-counting CT and effectively increasing utilization in clinical practice.; Bibliometric analysis is fundamental to understanding the current and future state of dual- and multi-energy CT. Research trends and leading topics included coronary artery disease, pulmonary embolism, and radiation dose. All analyses indicate a growing interest in the use of energy-based imaging techniques for thoracic applications.; © 2024. The Author(s).",15,1,209,,Medicine; Bibliometrics; Medical physics; Thematic map; Coronary artery disease; Radiology; Library science; Computer science; Geography; Cartography; Internal medicine,Bibliometric analysis; Dual-energy X-ray absorptiometry; Thoracic disease; X-ray computed tomography,,,National Natural Science Foundation of China (82102128); National Natural Science Foundation of China (82102128); National Natural Science Foundation of China (82102128); National Natural Science Foundation of China (82102128); National Natural Science Foundation of China (82102128); National Natural Science Foundation of China (82102128); National Natural Science Foundation of China (82102128); National Natural Science Foundation of China (82102128); Zhejiang Provincial Natural Science Foundation of China (LTGY23H180001),,http://dx.doi.org/10.1186/s13244-024-01788-4,39143273,10.1186/s13244-024-01788-4,,PMC11324624,0,002-052-422-936-00X; 009-146-016-090-928; 012-860-917-091-350; 013-507-404-965-47X; 016-286-700-955-084; 017-781-416-062-849; 021-928-811-880-022; 028-519-952-143-162; 028-857-224-734-070; 036-303-409-057-913; 039-591-012-524-868; 039-755-049-794-739; 042-717-487-126-221; 046-306-601-007-63X; 046-992-864-415-70X; 057-803-697-074-453; 061-749-564-630-559; 062-974-894-415-55X; 064-002-915-191-388; 064-400-499-357-900; 071-209-335-857-157; 078-420-477-807-794; 078-618-382-711-953; 078-816-590-028-689; 081-718-359-411-668; 083-597-222-672-271; 088-952-270-620-316; 089-920-830-471-620; 091-342-174-273-350; 091-999-751-057-014; 113-720-326-542-84X; 119-512-469-978-474; 125-831-582-783-658; 140-365-785-045-135; 142-785-616-641-941; 159-635-948-403-150; 175-256-218-331-36X; 184-332-380-542-315,1,true,cc-by,gold -050-902-937-162-68X,The formation of a field: sustainability science and its leading journals,2023-11-24,2023,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Marco Schirone,"AbstractThis study investigates the scholarly field of sustainability science between 2001 and 2021 from the perspective of 18 frequently cited journals. For this purpose, the article employs the concept of the “scientific field” developed by the sociologist Pierre Bourdieu and the associated methodology of Geometric Data Analysis (GDA). Thus, two GDA approaches, the Principal Component Analysis (PCA) and the Multiple Correspondence Analysis (MCA), as well as analyses of co-citation and co-authorship relations, were used to identify the positions of these journals in the field. One key finding is the historical shift from an earlier dominance of chemistry-related journals to publications more broadly concerned with sustainability research. The MCA analyses show that the selection of research topics is in line with a “weak” rather than “strong” interpretation of the concept “sustainability.” Networks based on co-authorship relations reveal an overall increment in this type of collaboration, both at the level of organizations and countries. Since 2008, Chinese universities have notably increased their presence in the output of the journals examined in the study. Three strategies in shaping the field through its journals are discernable: publications strongly characterized by a systems theory perspective, notably Sustainability Science; generalist journals committed to sustainability research in a broader meaning; and publications that address sustainability issues mainly within a specific discipline.",129,1,401,429,Sustainability; Field (mathematics); Dominance (genetics); Sustainability science; Perspective (graphical); Sociology; Interpretation (philosophy); Social science; Engineering ethics; Epistemology; Political science; Computer science; Sustainability organizations; Ecology; Engineering; Philosophy; Chemistry; Biochemistry; Programming language; Mathematics; Artificial intelligence; Biology; Pure mathematics; Gene,,,,University of Boras,https://link.springer.com/content/pdf/10.1007/s11192-023-04877-1.pdf https://doi.org/10.1007/s11192-023-04877-1,http://dx.doi.org/10.1007/s11192-023-04877-1,,10.1007/s11192-023-04877-1,,,0,002-052-422-936-00X; 005-394-809-940-272; 006-808-502-767-966; 006-995-721-844-972; 010-469-466-140-912; 010-767-257-442-290; 013-043-630-163-202; 013-302-277-213-718; 013-507-404-965-47X; 015-417-353-767-484; 016-715-105-170-779; 017-964-051-494-113; 019-969-825-497-904; 020-031-223-301-351; 021-606-332-513-848; 024-430-199-030-793; 031-096-825-110-831; 031-802-017-110-046; 031-907-418-698-267; 033-368-836-188-49X; 034-171-490-691-342; 035-298-473-554-092; 035-494-531-596-791; 036-149-857-185-318; 037-815-640-424-494; 039-504-966-877-199; 039-938-739-884-303; 041-406-342-008-561; 041-522-407-456-591; 044-009-235-922-26X; 051-253-199-940-986; 052-739-406-887-281; 056-514-480-201-346; 057-014-227-671-075; 057-325-596-085-547; 058-176-661-846-710; 061-546-004-779-769; 064-401-554-623-963; 065-249-987-578-70X; 065-448-277-246-278; 066-808-002-387-074; 068-909-072-061-315; 070-599-924-880-048; 072-921-999-318-899; 073-705-593-692-178; 073-775-823-470-313; 078-762-062-751-821; 079-594-320-592-955; 081-664-572-771-135; 088-414-448-215-329; 088-861-468-623-818; 089-396-826-440-313; 089-910-503-281-767; 095-678-165-156-472; 096-138-680-266-472; 098-378-936-820-680; 099-475-517-395-289; 106-514-875-380-838; 110-087-358-522-210; 112-390-695-192-691; 119-383-816-422-289; 123-916-203-428-067; 126-329-734-545-599; 127-888-175-189-168; 129-724-603-205-454; 138-270-687-058-342; 142-951-755-290-361; 146-554-026-549-843; 148-692-136-017-168; 151-542-551-704-330; 157-709-134-058-016; 163-356-655-576-851; 165-385-481-718-260; 173-620-304-351-936; 175-013-997-072-443; 179-178-729-068-270; 180-178-506-396-993; 186-881-919-861-841; 193-561-922-927-38X; 197-655-278-248-767,3,true,cc-by,hybrid -051-137-195-092-504,Towards an understanding of landslide risk assessment and its economic losses: a scientometric analysis,2024-05-11,2024,journal article,Landslides,1612510x; 16125118,Springer Science and Business Media LLC,Germany,Nini Johana Marín-Rodríguez; Johnny Vega; Oscar Betancurt Zanabria; Juan David González-Ruiz; Sergio Botero,"AbstractThis scientometric analysis significantly advances the understanding of landslide risk assessment and economic losses, focusing on scientometric insights. This study aims at analyzing the global trends and structures of landslide risk and economic loss research from 2002 to 2023 using scientometric techniques such as co-authorship, co-word, co-citation, cluster analysis, and trend topics, among others. Thus, analysis of 92 studies gathered from Scopus and Web of Science databases reveals a continuous growth in environmental, social, and quantitative research topics. Predominant contributions hail mainly from China and Italy. The research identifies critical themes, including risk analysis, vulnerability, fragility, and economic losses. The current identified research combines advanced statistical methods, including logistic regression, with climate change scenarios and susceptibility assessments to reveal intricate connections between climatic shifts, hydrogeological hazards, and their economic and environmental impacts. This study provides researchers and practitioners with a comprehensive understanding of the status quo and research trends of ontology research landslide risk and its economic losses. It also promotes further studies in this domain.",21,8,1865,1881,Scopus; Landslide; Natural hazard; Vulnerability (computing); Geography; Status quo; Climate change; Vulnerability assessment; Environmental resource management; Risk analysis (engineering); Regional science; Political science; Environmental science; Business; Computer science; Engineering; Psychology; MEDLINE; Psychological resilience; Ecology; Meteorology; Computer security; Geotechnical engineering; Law; Psychotherapist; Biology,,,,University of Medellin,https://link.springer.com/content/pdf/10.1007/s10346-024-02272-2.pdf https://doi.org/10.1007/s10346-024-02272-2,http://dx.doi.org/10.1007/s10346-024-02272-2,,10.1007/s10346-024-02272-2,,,0,001-148-067-432-463; 002-641-901-425-296; 002-932-261-234-079; 007-892-615-171-369; 008-367-923-675-148; 011-301-822-302-672; 012-158-458-605-331; 012-381-348-005-468; 013-507-404-965-47X; 013-667-083-336-818; 018-114-773-173-229; 020-642-507-139-475; 023-594-648-565-860; 024-680-464-823-818; 025-799-130-403-295; 032-960-513-100-904; 037-017-227-977-339; 039-016-401-317-183; 040-344-385-236-719; 042-055-801-396-60X; 042-668-535-027-335; 042-900-411-803-703; 043-004-325-637-906; 044-461-658-338-197; 044-680-324-946-256; 053-455-599-379-882; 056-633-656-580-864; 058-447-493-824-150; 061-038-747-180-430; 062-919-029-879-868; 063-269-459-628-860; 075-613-676-467-659; 077-983-649-606-677; 081-504-930-734-850; 082-336-079-636-312; 093-555-996-579-545; 107-577-768-997-909; 113-606-119-171-928; 120-308-201-978-008; 125-325-924-202-648; 127-799-323-513-632; 131-719-680-162-879; 138-534-531-029-883; 143-740-397-009-141; 145-188-359-090-993; 147-043-660-615-790; 147-691-850-913-17X; 148-092-457-460-073; 157-826-626-786-987; 158-926-689-337-091; 159-545-845-252-290; 161-182-566-480-495; 178-608-217-334-644; 197-746-351-040-043,16,true,cc-by,hybrid -051-137-464-539-694,Sistemas de Información Geográficos (SIG) basadas en arquitectura WebGIS. Un análisis bibliométrico del estado actual y tendencias de la investigación.,2023-11-17,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Jorge Vinueza Martínez; Mirella Correa-Peralta; Richard Ramirez-Anormaliza; Omar Franco Arias; Daniel Vera Paredes,Este artículo presenta una revisión de la literatura mediante un estudio bibliométrico en el campo de los sistemas de información desde 2002 a 2023. El estudio recopiló 358 publicaciones sobre arquitecturas WebGIS en las últimas dos décadas y utilizó Bibliometrix y Biblioshiny para su análisis.,,,,,Geography; Humanities; Cartography; Art,,,,,https://zenodo.org/doi/10.5281/zenodo.10149926,http://dx.doi.org/10.5281/zenodo.10149926,,10.5281/zenodo.10149926,,,0,,0,true,cc-by,gold -051-280-021-856-254,Exploring the challenges and benefits for scaling agile project management to large projects: a review,2021-10-25,2021,journal article,Requirements Engineering,09473602; 1432010x,Springer Science and Business Media LLC,Germany,Paula de Oliveira Santos; Marly Monteiro de Carvalho,,27,1,117,134,,,,,Conselho Nacional de Desenvolvimento Científico e Tecnológico,,http://dx.doi.org/10.1007/s00766-021-00363-3,,10.1007/s00766-021-00363-3,,,0,000-643-591-454-53X; 001-243-823-282-137; 003-018-998-962-320; 003-282-247-755-606; 004-341-381-677-198; 004-917-081-535-832; 005-830-190-332-158; 006-109-505-987-355; 010-708-983-768-041; 011-682-063-667-057; 011-706-003-053-874; 011-876-046-027-467; 011-906-177-779-911; 012-718-180-038-258; 013-507-404-965-47X; 014-636-391-584-412; 015-632-508-341-595; 015-878-670-525-296; 016-111-387-578-344; 016-167-579-543-608; 016-687-577-382-256; 016-762-469-904-472; 018-471-830-030-116; 018-528-540-246-781; 021-399-692-309-155; 021-579-146-110-577; 021-743-435-026-269; 022-304-790-542-067; 024-449-688-439-995; 027-232-433-065-559; 033-929-816-703-041; 033-936-548-547-964; 036-615-479-671-743; 037-043-673-626-28X; 037-615-826-238-167; 038-241-723-573-82X; 040-736-307-019-439; 043-859-681-219-819; 045-791-347-593-172; 046-389-606-812-052; 046-557-180-865-199; 050-756-772-786-140; 051-322-204-345-580; 052-428-200-577-917; 053-501-378-659-551; 053-683-005-086-543; 058-017-142-264-577; 058-952-131-996-665; 060-455-060-437-894; 063-046-385-849-899; 063-551-092-877-973; 063-710-848-225-090; 064-535-728-352-926; 064-900-730-136-395; 065-632-373-701-015; 066-856-459-144-618; 066-959-128-540-183; 068-799-139-587-297; 070-635-125-631-454; 072-551-758-933-107; 072-826-840-734-342; 075-853-099-990-126; 080-570-679-806-04X; 081-727-051-993-299; 082-294-719-924-361; 086-688-814-869-687; 088-130-799-270-317; 089-304-379-780-672; 092-213-774-218-377; 096-282-608-175-45X; 100-277-722-551-670; 103-996-224-454-43X; 111-540-078-017-788; 111-919-507-697-467; 114-956-082-609-389; 115-195-785-551-307; 116-294-538-779-46X; 119-481-907-894-571; 119-516-396-653-879; 119-640-828-086-758; 125-701-565-652-757; 129-698-109-108-230; 130-057-480-639-007; 130-271-594-641-751; 130-474-447-657-024; 139-781-709-282-937; 142-691-733-133-578; 144-833-454-900-096; 146-287-196-239-887; 149-837-796-326-346; 152-771-655-811-056; 156-981-724-274-671; 172-389-560-900-257; 175-985-894-679-556,28,false,, -051-471-138-452-968,Apis Mellifera Animal Study in a Role Perspective Using the Bibliometrix Tools (SLNA Method Application),2023-04-02,2023,journal article,Jurnal Mangifera Edu,26223384; 25279939,Universitas Wiralodra,,Ida Yayu Nurul Hizqiyah; null Armansyah Putra; null Meili Yanti; null Unayah; null Mia Nurkanti; null Nia Nurdiani,"There is no research on the study of Apis mellifera using bibliometrix tools. This study aims to determine the results of the study of Apis mellifera in a role perspective using Bibliometrix Tools. This study uses an approach that uses the Systematic Literature Network Analysis (SLNA) method assisted by bibliometrix tools in the form of four applications OpenRefine, VOSviewer, Bibliometrix, and Tableau Public. The data source used is the Scopus database. This study uses a confirmability test. Journals that publish many articles about Apis mellifera include Apidologie, Insects, and Scientific Reports. Authors who publish a lot of articles about Apis mellifera include Neumann P number 32, Chen Y and Le Conte Y number 20. The years that published a lot of articles about Apis mellifera are 2021 and 2020. The theme network consists of 5 clusters the farther the distance between topics it means that people rarely research about the topic/theme. Apis mellifera is the dominant pollinating insect that helps in the process of pollinating many plants such as blueberries and other roles, namely as medicine, from propolis to honey bee cocoons. Meanwhile, the detrimental role caused by Apis mellifera honey bees and other pollinating insects is as a vector of diseases that causes the carrying of bad bacteria that can attack plants which of course will reduce production yields.",7,2,119,134,Honey bee; Theme (computing); Publication; Pollination; Honey Bees; Biology; Perspective (graphical); Beekeeping; Scopus; World Wide Web; Computer science; Ecology; Pollen; Artificial intelligence; Advertising; MEDLINE; Biochemistry; Business,,,,,https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/download/159/98 https://doi.org/10.31943/mangiferaedu.v7i2.159,http://dx.doi.org/10.31943/mangiferaedu.v7i2.159,,10.31943/mangiferaedu.v7i2.159,,,0,,0,true,cc-by-sa,gold -052-043-821-107-064,Economists in Ukraine: who are they and where do they publish?,2018-03-01,2018,,Research Papers in Economics,,,,Maksym Obrizan,"This paper analyses 1,672 articles published in English by economists working in Ukraine over 1991-2017 using SCOPUS database and bibliometrix package in R. Between 2011 and 2012 when the number of published papers increased more than ten times with Actual Problems of Economics and Economic Annals-XXI being the two most important outlets accounting for more than 70 percent of all publications. Despite this increased visibility the citation counts show rather modest contribution of economists in Ukraine. Regression analysis of citations indicates that articles with a foreign co-author and Digital Object Identifier are more likely to receive citations.",,,,,Regression analysis; Library science; Political science; Bibliometrics; Ranking; Citation; Visibility (geometry); Digital Object Identifier; Publication; Scopus,,,,,https://ideas.repec.org/p/rcd/wpaper/3181.html https://econpapers.repec.org/RePEc:rcd:wpaper:3181,https://ideas.repec.org/p/rcd/wpaper/3181.html,,,2810980597,,0,,0,false,, -052-096-570-094-906,"Bibliometric analysis of the contribution of internal communication, managerial accounting and control tools in the management of production activities",,2024,conference proceedings article,International Scientific Conference on Accounting ISCA 2024,,Academy of Economic Studies of Moldova,,Corina Petrescu; Veronica Grosu,"The image or overall performance of a company is determined by many internal and external factors that exert a more or less marked influence on it, depending on the specifics and characteristics of the activity carried out. This paper focuses on the importance of the interconnectivity of business functions related to internal communication, managerial accounting and control tools in the efficient and effective management of production activity. Bibliometric analysis of the literature was carried out using VosViewer and Bibliometrix software, and the determined variables were used for the analysis of the interconnectivity of the analyzed areas by means of the cluster method, statistical processing was carried out using SPSS v.26 software. The results demonstrate a significant positive correlation between the analyzed domains, as they play a significant role in the internal and external evaluation of a company, but they also require a more in-depth and updated approach to the concepts, appropriate to the new interests and trends existing in the economic environment.",,,158,167,Interconnectivity; Control (management); Production (economics); Computer science; Knowledge management; Software; Accounting; Business; Process management; Economics; Artificial intelligence; Macroeconomics; Programming language,,,,,,http://dx.doi.org/10.53486/isca2024.22,,10.53486/isca2024.22,,,0,,0,false,, -052-149-855-788-705,Bibliometric Analysis of Indian Journal of Palliative Care from 1995 to 2022 using the VOSviewer and Bibliometrix Software.,2022-08-24,2022,journal article,Indian journal of palliative care,09731075; 19983735,Scientific Scholar,India,Rajashree Srivastava; Shikha Srivastava,"The Indian Journal of Palliative Care (IJPC) is an open-source, interdisciplinary and peer-reviewed journal started in 1994 that publishes high-quality articles in the field of palliative care in India. The purpose of this study is to analyse the bibliometric data of its publications using bibliometric analysis to understand the key bibliometric factors affecting the journal and its contribution to the field of palliative care research.; A software-assisted bibliometric analysis of the IJPC was conducted. The dimensions database was used to mine the bibliometric data of the journal from 1995 to 2022. A total of 1046 records were analysed using the VOSviewer and Biblioshiny by Bibliometrix software.; The analysis represented a vivid and graphically elaborate picture of the journal. It gives insight into the most productive and influential authors, countries, affiliations, sources and documents along with a picture of the network among them.; This study highlights a gradual upward trend in the annual production of the journal. A strong connection of the IJPC could be seen with leading journals publishing in the field of palliative care globally.; © 2022 Published by Scientific Scholar on behalf of Indian Journal of Palliative Care.",28,4,338,353,Palliative care; Publishing; Bibliometrics; Library science; Medicine; Computer science; Nursing; Political science; Law,Bibliometrics; Indian journal of palliative care; Single journal study; VOSviewer; Visual mapping,,,,,http://dx.doi.org/10.25259/ijpc_30_2022,36447508,10.25259/ijpc_30_2022,,PMC9699919,0,000-089-909-958-821; 001-083-216-255-479; 002-052-422-936-00X; 003-813-061-247-291; 009-733-989-472-056; 011-003-284-329-951; 011-320-915-051-255; 013-507-404-965-47X; 013-996-749-102-08X; 022-580-839-956-529; 025-994-911-488-811; 026-418-010-787-233; 031-558-700-345-462; 032-916-438-693-237; 033-928-141-564-105; 034-058-538-646-125; 040-452-806-006-099; 043-678-545-624-032; 046-992-864-415-70X; 054-818-565-070-154; 058-412-979-777-489; 059-110-900-015-557; 060-781-260-517-577; 064-674-585-297-201; 076-825-555-113-580; 106-503-170-381-01X; 111-911-102-968-883; 123-574-401-810-227; 141-928-929-765-696,10,true,,gold -052-183-395-751-766,Exploring the trends of research: a bibliometric analysis of global ship emission estimation practices,2024-08-29,2024,journal article,Journal of Ocean Engineering and Marine Energy,21986444; 21986452,Springer Science and Business Media LLC,,Kazi Mohiuddin; Md Nadimul Akram; Md Mazharul Islam; Marufa Easmin Shormi; Xuefeng Wang,,10,4,963,985,Estimation; Regional science; Data science; Geography; Computer science; Engineering; Systems engineering,,,,,,http://dx.doi.org/10.1007/s40722-024-00341-1,,10.1007/s40722-024-00341-1,,,0,000-848-264-004-813; 001-148-423-266-984; 001-472-053-734-617; 002-652-547-770-719; 002-740-929-439-802; 003-137-841-319-996; 003-881-271-132-550; 004-092-436-774-549; 004-961-007-187-727; 006-116-603-160-867; 007-517-359-957-332; 008-915-442-566-279; 010-548-736-009-857; 011-664-524-179-517; 013-011-005-710-331; 013-410-339-595-60X; 013-507-404-965-47X; 014-248-234-962-331; 014-291-565-416-654; 017-389-862-962-576; 017-794-416-315-079; 018-665-326-051-757; 018-726-732-663-114; 018-955-231-541-353; 021-030-047-148-213; 022-655-903-542-691; 022-898-421-120-409; 022-939-129-772-395; 023-527-718-075-323; 024-587-976-796-917; 026-074-034-588-208; 026-300-903-219-379; 026-738-824-421-866; 026-845-733-807-089; 026-866-236-868-940; 028-148-441-645-03X; 028-591-917-577-885; 031-851-582-634-628; 032-719-752-596-248; 033-770-367-052-615; 036-003-798-140-467; 038-920-856-938-428; 039-394-749-206-992; 040-944-543-859-313; 042-066-682-589-284; 042-377-140-039-550; 042-542-640-274-692; 042-897-828-941-736; 043-174-971-006-174; 044-053-399-512-759; 044-340-201-500-819; 044-559-763-650-989; 045-600-746-536-795; 046-420-290-891-235; 046-724-640-777-671; 047-309-867-227-533; 047-763-810-139-09X; 048-327-683-909-447; 049-102-424-228-435; 049-300-295-492-383; 049-596-297-920-543; 049-734-307-946-142; 050-841-398-856-511; 050-944-050-900-94X; 051-534-636-566-808; 052-898-304-814-485; 054-483-115-006-778; 054-995-221-269-458; 055-222-575-590-371; 055-774-627-906-098; 056-800-092-150-062; 056-991-407-720-037; 058-727-761-629-279; 059-849-885-191-127; 060-858-452-004-955; 061-617-302-432-005; 063-875-731-225-578; 065-204-184-464-304; 066-006-282-087-783; 067-271-183-602-966; 067-509-080-881-840; 067-585-654-343-035; 067-599-247-336-839; 068-836-871-585-372; 069-645-422-279-059; 070-588-469-149-865; 072-691-457-855-621; 072-771-523-538-131; 073-681-956-263-118; 074-058-824-404-873; 074-448-057-759-860; 074-884-727-282-346; 074-986-823-045-401; 075-017-688-027-297; 075-414-919-972-00X; 075-559-537-261-971; 083-379-014-902-380; 084-550-824-035-42X; 084-819-338-190-36X; 086-333-841-440-648; 088-321-366-188-774; 089-875-507-737-003; 090-003-318-643-558; 092-091-314-148-010; 093-793-011-663-958; 096-474-214-374-276; 097-003-037-241-530; 097-278-048-789-318; 100-369-783-776-732; 100-690-924-443-271; 100-876-477-036-257; 101-809-083-070-627; 103-571-217-435-35X; 106-281-186-898-40X; 108-595-992-715-449; 108-623-434-228-895; 110-061-919-936-136; 111-253-899-959-631; 121-292-421-008-559; 124-602-067-693-054; 129-155-228-607-445; 131-646-106-752-319; 134-898-066-369-699; 136-093-293-636-317; 136-174-225-108-373; 138-461-856-928-049; 139-100-351-565-425; 141-524-674-881-749; 142-509-183-021-323; 147-725-168-687-993; 148-048-348-719-64X; 149-596-036-532-388; 154-888-089-423-025; 155-360-409-431-667; 161-329-402-673-569; 162-760-348-064-256; 162-948-785-907-578; 164-135-271-734-811; 167-327-130-944-503; 169-743-403-021-735; 175-805-773-469-818; 177-737-452-234-04X; 177-951-973-507-08X; 182-826-619-637-55X; 183-161-662-826-535; 183-604-860-435-498; 186-871-937-845-184; 186-983-383-512-228; 189-156-359-091-339; 189-805-886-776-847; 199-018-907-185-238,0,false,, -052-251-970-098-073,Systematic Literature Review on Academic Entrepreneurship by Bibliometric Metadata Analysis,2022-09-09,2022,journal article,International Journal of Social Science Studies,23248041; 23248033,Redfame Publishing,,Marco Antonio Domingues; Hortência E Pereira Santana; Denise Santos Ruzene; Daniel Pereira Silva,"The purpose of this article is to map the field of Academic Entrepreneurship focusing on the search for models that evaluate the viability of intellectual property as a product. The study was based on articles retrieved from the Web of Science database covering the period from 1988 to 2020, where the metadata data analysis was carried out using the RStudio software, bibliometrix package, and the web interface Biblioshiny, and a systematic review was conducted following the PRISMA protocol, Extension for Scoping Reviews. The findings revealed that the main objectives of studies on academic entrepreneurship are related to the analysis of human (training, leadership, and motivation), physical and management resources, as they are pointed out as the most necessary incentives to improve universities AE. Therefore, it was concluded that most models on AE are for the evaluation of the development of entrepreneurship in the academic environment and there is a research gap to develop models aiming at the commercialization of intellectual property.",10,5,33,33,Entrepreneurship; Metadata; Commercialization; Incentive; Systematic review; Knowledge management; Field (mathematics); Scopus; Content analysis; Computer science; Data science; Sociology; Business; World Wide Web; Political science; Marketing; Social science; Economics; MEDLINE; Mathematics; Finance; Pure mathematics; Law; Microeconomics,,,,,https://redfame.com/journal/index.php/ijsss/article/download/5647/5843 https://doi.org/10.11114/ijsss.v10i5.5647,http://dx.doi.org/10.11114/ijsss.v10i5.5647,,10.11114/ijsss.v10i5.5647,,,0,,0,true,,gold -052-321-055-829-793,A bibliometric analysis of m6A methylation in viral infection from 2000 to 2022.,2024-01-18,2024,journal article,Virology journal,1743422x,Springer Science and Business Media LLC,United Kingdom,Xing Tao; Gang Wang; Wudi Wei; Jinming Su; Xiu Chen; Minjuan Shi; Yinlu Liao; Tongxue Qin; Yuting Wu; Beibei Lu; Hao Liang; Li Ye; Junjun Jiang,"N6-methyladenosine (m6A) methylation has become an active research area in viral infection, while little bibliometric analysis has been performed. In this study, we aim to visualize hotspots and trends using bibliometric analysis to provide a comprehensive and objective overview of the current research dynamics in this field.; The data related to m6A methylation in viral infection were obtained through the Web of Science Core Collection form 2000 to 2022. To reduce bias, the literature search was conducted on December 1, 2022. Bibliometric and visual analyzes were performed using CiteSpace and Bibliometrix package. After screening, 319 qualified records were retrieved.; These publications mainly came from 28 countries led by China and the United States (the US), with the US ranking highest in terms of total link strength.The most common keywords were m6A, COVID-19, epitranscriptomics, METTL3, hepatitis B virus, innate immunity and human immunodeficiency virus 1. The thematic map showed that METTL3, plant viruses, cancer progression and type I interferon (IFN-I) reflected a good development trend and might become a research hotspot in the future, while post-transcriptional modification, as an emerging or declining theme, might not develop well.; In conclusion, m6A methylation in viral infection is an increasingly important topic in articles. METTL3, plant viruses, cancer progression and IFN-I may still be research hotspots and trends in the future.; © 2024. The Author(s).",21,1,20,,Biology; DNA methylation; China; Virology; Web of science; MEDLINE; Geography; Genetics; Gene; Biochemistry; Gene expression; Archaeology,Bibliometric analysis; Data visualization; Methylation; N6-methyladenosine; Viral infection,Humans; Virus Diseases; Bibliometrics; Interferon Type I; Methylation; Neoplasms; Methyltransferases; Adenine/analogs & derivatives,"6-methyladenine; Interferon Type I; METTL3 protein, human; Methyltransferases; Adenine",Innovation Project of Guangxi Graduate Education (YCSW2022198); National Natural Science Foundation of China (82103898),https://virologyj.biomedcentral.com/counter/pdf/10.1186/s12985-024-02294-1 https://doi.org/10.1186/s12985-024-02294-1,http://dx.doi.org/10.1186/s12985-024-02294-1,38238848,10.1186/s12985-024-02294-1,,PMC10797797,0,000-033-908-957-365; 002-139-903-723-04X; 003-472-850-488-503; 004-188-420-529-983; 004-849-632-585-878; 006-114-505-907-833; 006-207-789-061-384; 007-324-393-010-088; 007-589-729-747-870; 014-186-888-360-881; 014-505-731-314-401; 015-800-433-225-097; 016-451-680-976-983; 019-085-913-941-290; 019-378-661-474-719; 021-768-391-378-748; 022-796-353-618-354; 035-468-425-502-537; 036-515-522-540-055; 037-376-164-044-535; 038-741-992-471-013; 038-781-613-244-184; 039-511-820-240-289; 042-937-864-460-378; 045-353-873-478-748; 046-089-236-095-29X; 046-457-900-689-069; 048-058-196-699-523; 050-123-601-984-724; 052-301-700-689-327; 063-970-441-781-969; 071-985-543-971-79X; 079-395-576-232-855; 098-230-357-481-388; 101-774-754-292-283; 102-210-320-317-263; 102-242-617-018-586; 103-823-497-091-341; 105-760-483-053-472; 108-952-585-216-944; 114-232-598-376-615; 116-053-282-572-125; 121-024-404-718-865; 131-462-279-746-199; 182-894-774-073-947,1,true,"CC BY, CC0",gold -052-494-799-823-795,"A bibliometric analysis of artificial intelligence in language teaching and learning (1990–2023): evolution, trends and future directions",2024-06-22,2024,journal article,Education and Information Technologies,13602357; 15737608,Springer Science and Business Media LLC,United Kingdom,Huiling Ma; Lilliati Ismail; Weijing Han,,29,18,25211,25235,Educational technology; Computer science; Mathematics education; Computer-Assisted Instruction; Trend analysis; Science education; Data science; Artificial intelligence; Psychology; Multimedia; Machine learning,,,,,,http://dx.doi.org/10.1007/s10639-024-12848-z,,10.1007/s10639-024-12848-z,,,0,000-452-908-115-500; 006-017-689-911-743; 008-030-497-805-03X; 008-708-960-845-751; 009-445-245-620-507; 010-408-829-011-185; 015-794-966-455-815; 022-583-014-690-387; 026-739-753-532-124; 031-600-858-204-981; 031-879-521-929-232; 033-146-917-697-68X; 036-795-017-721-604; 039-450-810-945-254; 041-627-165-827-281; 044-247-222-375-416; 045-842-196-133-132; 046-336-866-196-867; 049-391-379-302-694; 056-849-757-952-252; 058-156-023-995-836; 059-939-595-461-351; 068-078-971-268-091; 068-459-798-053-44X; 069-245-378-755-923; 074-191-317-542-908; 077-042-753-442-444; 081-106-397-388-676; 083-435-927-301-567; 087-256-043-038-339; 091-284-537-237-656; 094-944-053-769-074; 100-812-748-947-667; 105-789-171-897-536; 107-262-715-167-286; 111-768-496-377-592; 112-203-464-117-129; 120-509-043-966-319; 131-351-117-172-178; 148-484-147-650-616; 154-886-633-775-050; 163-657-932-933-431; 179-749-910-991-947,6,false,, -052-690-334-264-610,Trends and patterns in digital marketing research: bibliometric analysis,2021-08-12,2021,journal article,Journal of Marketing Analytics,20503318; 20503326,Springer Science and Business Media LLC,,Zahra Ghorbani; Sanaz Kargaran; Ali Saberi; Manijeh Haghighinasab; Seyedh Mahboobeh Jamali; Nader Ale Ebrahim,,10,2,158,172,,,,,,,http://dx.doi.org/10.1057/s41270-021-00116-9,,10.1057/s41270-021-00116-9,,,0,000-813-346-944-622; 002-052-422-936-00X; 007-141-694-325-68X; 007-239-639-410-334; 008-746-289-270-070; 010-149-389-410-815; 011-854-399-312-637; 012-564-341-487-195; 013-205-880-192-312; 013-507-404-965-47X; 020-267-512-748-775; 022-256-440-443-532; 023-244-927-030-914; 032-652-789-144-241; 033-566-879-288-578; 034-061-507-513-546; 035-803-463-928-999; 036-659-005-806-663; 038-268-765-985-355; 038-480-768-133-172; 044-870-444-750-124; 044-975-327-380-92X; 045-717-084-226-016; 049-285-500-063-383; 053-139-268-115-60X; 055-026-956-557-227; 055-209-711-625-094; 056-952-559-351-611; 079-834-303-093-847; 079-927-063-877-695; 081-937-141-701-021; 085-742-825-630-565; 085-992-385-787-308; 088-649-913-252-966; 095-416-199-518-718; 096-922-027-049-781; 098-185-949-017-845; 103-199-876-285-449; 105-312-629-686-637; 107-895-477-453-200; 108-292-656-930-774; 112-497-027-462-860; 112-682-554-554-606; 118-419-501-591-315; 120-287-191-268-212; 123-403-938-885-273; 124-073-110-685-543; 126-805-675-662-019; 130-057-480-639-007; 140-785-850-542-009; 148-356-973-354-345; 148-655-801-790-108; 148-953-220-371-138; 149-691-936-196-995; 156-288-466-403-227; 169-622-998-491-70X,39,false,, -053-594-779-403-421,Current global status of Candida auris an emerging multidrug-resistant fungal pathogen: bibliometric analysis and network visualization.,2024-01-23,2024,journal article,Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology],16784405; 15178382,Springer Science and Business Media LLC,Brazil,Hamza Ettadili; Caner Vural,"Candida auris is an emerging multidrug-resistant fungal pathogen associated with nosocomial infections and hospital outbreaks worldwide, presenting a serious global health threat. There has been a rapid emergence of scientific research publications focusing on therapeutic compounds, diagnostic techniques, control strategies, prevention, and understanding the epidemiology related to C. auris.; This study aims to provide the most up-to-date comprehensive and integrated examination of C. auris research subject and demonstrate that C. auris is indeed a topic of increasing interest.; The search query ""candida-auris"" was used as a topic term to find and retrieve relevant data published between 2009 and 15 June 2023, from the Web of Science Core Collection (WoSCC) database. In this work, the bibliometric analysis and network visualization were conducted using VOSviewer software, and Biblioshiny interface accessible through the Bibliometrix R-package on RStudio software.; The yearly growth rate percentage (37.91%), along with the strong positive correlations between publications and citations (r = 0.981; p < 0.001), suggests heightened scholarly engagement in this topic. The USA, India, China, and the UK have emerged as pivotal contributors, with the Centers for Disease Control and Prevention (CDC) in the USA being the most productive institution. Current research hotspots in this field mainly focused on identifying and limiting transmission of the clonal strains, epidemiology, antifungal resistance, and in vitro antifungal susceptibility testing.; This detailed bibliometric analysis in C. auris topic shows that this fungal pathogen has garnered growing attention and attracted progressively more scholars. This paper will help researchers to find without difficulty the relevant articles, research hotspots, influential authors, institutions, and countries related to the topic.; © 2024. The Author(s) under exclusive licence to Sociedade Brasileira de Microbiologia.",55,1,391,402,Candida auris; Fluconazole; Biology; Data science; Medicine; Antifungal; Computer science; Microbiology,"Candida auris - ; Bibliometrics; Candidiasis; Fungal pathogen; R-bibliometrix; Responsible Editor: Rosana Puccia; VOSviewer",Humans; Candida; Candidiasis/microbiology; Candida auris; Antifungal Agents/pharmacology; Fungi; Microbial Sensitivity Tests,Antifungal Agents,,,http://dx.doi.org/10.1007/s42770-023-01239-0,38261261,10.1007/s42770-023-01239-0,,PMC10920528,0,000-020-955-468-991; 001-659-351-398-818; 002-052-422-936-00X; 002-943-143-485-348; 003-542-973-869-77X; 004-805-726-293-804; 007-791-545-334-923; 010-285-600-084-397; 013-507-404-965-47X; 015-963-880-726-025; 017-969-398-639-089; 018-692-771-958-254; 018-743-913-770-378; 023-706-004-964-528; 023-930-459-038-906; 024-740-050-478-390; 025-814-831-427-671; 026-020-314-032-024; 026-207-102-450-558; 026-388-759-859-871; 026-543-982-506-267; 031-025-637-409-280; 032-297-797-492-832; 035-651-214-901-429; 036-176-302-529-870; 037-026-113-328-503; 045-410-561-407-56X; 046-992-864-415-70X; 047-057-174-976-154; 049-760-839-516-927; 050-759-876-943-888; 050-879-512-006-849; 053-808-504-544-082; 062-039-072-725-746; 063-055-124-486-561; 063-587-950-054-59X; 069-276-764-257-027; 069-390-795-936-507; 070-496-836-799-643; 072-618-880-131-419; 076-820-557-788-60X; 080-948-087-553-458; 082-645-835-589-574; 088-530-835-250-878; 089-371-355-625-424; 093-575-168-206-792; 098-304-482-064-574; 102-599-629-583-779; 112-713-403-082-348; 116-411-376-801-272; 118-938-406-547-150; 122-010-303-407-119; 125-690-713-758-705; 128-827-209-390-052; 130-490-701-341-325; 140-981-396-588-362; 144-600-996-830-021; 151-283-237-500-432; 151-536-545-559-228; 152-624-495-882-241; 162-476-208-032-553; 168-344-514-696-597; 179-642-545-029-230; 185-267-924-884-160; 196-739-218-888-780,8,true,,unknown -053-655-227-481-25X,Co-production in health policy and management: a comprehensive bibliometric review,2020-06-05,2020,journal article,BMC health services research,14726963,Springer Science and Business Media LLC,United Kingdom,Floriana Fusco; Marta Marsilio; Chiara Guglielmetti,"Due to an increasingly elderly population, a higher incidence of chronic diseases and higher expectations regarding public service provision, healthcare services are under increasing strain to cut costs while maintaining quality. The importance of promoting systems of co-produced health between stakeholders has gained considerable traction both in the literature and in public sector policy debates. This study provides a comprehensive map of the extant literature and identifies the main themes and future research needs. A quantitative bibliometric analysis was carried out consisting of a performance analysis, science mapping, and a scientific collaboration analysis. Web of Science (WoS) was chosen to extract the dataset; the search was refined by language, i.e. English, and type of publication, i.e. journal academic articles and reviews. No time limitation was selected. The dataset is made up of 295 papers ranging from 1994 to May 2019. The analysis highlighted an annual percentage growth rate in the topic of co-production of about 25%. The articles retrieved are split between 1225 authors and 148 sources. This fragmentation was confirmed by the collaboration analysis, which revealed very few long-lasting collaborations. The scientific production is geographically polarised within the EU and Anglo-Saxon countries, with the United Kingdom playing a central role. The intellectual structure consists of three main areas: public administration and management, service management and knowledge translation literature. The co-word analysis confirms the relatively low scientific maturity of co-production applied to health services. It shows few well-developed and central terms, which refer to traditional areas of co-production (e.g. public health, social care), and some emerging themes related to social and health phenomena (e.g. the elderly and chronic diseases), the use of technologies, and the recent patient-centred approach to care (patient involvement/engagement). The field is still far from being mature. Empirical practices, especially regarding co-delivery and co-management as well as the evaluation of their real impacts on providers and on patients are lacking and should be more widely investigated.",20,1,1,16,Health administration; Public health; Health informatics; Public sector; Health care; Knowledge translation; Public service; Health policy and management; Public relations; Medicine,Bibliometric analysis; Co-citation analysis; Co-creation; Co-production; Co-word analysis; Health; Patient engagement; Science mapping,Bibliometrics; Delivery of Health Care/organization & administration; Health Policy; Humans; Stakeholder Participation; United Kingdom,,,https://air.unimi.it/bitstream/2434/732004/2/Fusco%2c%20Marsilio%2c%20Guglielmetti_BMC_2020.pdf https://doaj.org/article/183fb0dfcf2641f2bc3c79ba6c79c82b https://link.springer.com/article/10.1186/s12913-020-05241-2 https://link.springer.com/content/pdf/10.1186/s12913-020-05241-2.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275357 http://dx.doi.org/10.1186/s12913-020-05241-2 https://air.unimi.it/handle/2434/732004 https://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-020-05241-2 https://dx.doi.org/10.1186/s12913-020-05241-2 https://pubmed.ncbi.nlm.nih.gov/32503522/ https://core.ac.uk/download/322793081.pdf,http://dx.doi.org/10.1186/s12913-020-05241-2,32503522,10.1186/s12913-020-05241-2,3033801901,PMC7275357,0,001-564-492-994-494; 001-884-329-358-669; 003-635-859-873-268; 005-219-450-266-315; 005-590-991-432-327; 005-733-714-921-523; 005-996-901-358-144; 007-220-970-787-836; 007-795-098-160-316; 011-242-630-012-833; 011-364-541-838-073; 012-011-935-394-498; 012-822-108-382-222; 013-507-404-965-47X; 013-524-854-219-241; 016-298-743-829-879; 016-775-880-721-53X; 017-750-600-412-958; 018-117-234-373-508; 018-231-132-350-953; 019-219-882-433-111; 020-016-060-407-120; 020-625-321-792-279; 020-636-304-111-105; 021-493-763-999-271; 022-872-062-975-02X; 023-153-437-027-866; 023-446-117-683-345; 023-809-098-572-681; 024-119-309-428-689; 027-473-604-827-405; 027-506-299-223-119; 028-182-557-504-297; 028-674-394-011-797; 028-990-820-695-461; 029-175-204-162-405; 029-916-932-539-384; 029-985-292-842-260; 030-664-054-360-627; 031-531-051-422-754; 034-726-441-126-01X; 035-354-644-128-164; 035-435-053-288-005; 035-853-477-861-09X; 036-659-005-806-663; 036-883-207-978-224; 036-920-750-958-41X; 037-878-724-283-949; 038-346-695-038-686; 038-988-993-770-618; 039-194-275-881-550; 039-229-792-538-344; 041-679-586-558-088; 042-806-836-965-483; 044-354-597-287-934; 045-564-984-753-044; 045-909-700-984-336; 047-549-325-462-435; 048-690-281-133-478; 050-605-881-603-413; 051-580-214-888-150; 051-647-739-244-271; 051-997-139-517-678; 052-155-083-465-623; 053-038-743-933-650; 053-086-596-867-441; 054-818-565-070-154; 055-484-405-247-095; 056-724-502-391-87X; 062-400-865-746-023; 062-868-553-756-939; 063-878-208-002-47X; 064-319-324-934-587; 064-737-530-992-616; 065-461-101-401-816; 065-554-767-882-348; 067-497-414-383-177; 068-104-841-344-62X; 068-691-300-370-373; 070-212-018-137-202; 071-296-848-419-273; 073-367-985-641-83X; 074-609-047-649-398; 078-577-567-647-136; 080-845-533-944-95X; 082-551-986-485-281; 085-659-879-045-647; 087-900-406-238-087; 088-920-842-502-408; 089-311-036-332-937; 093-726-423-350-552; 098-009-689-044-333; 099-349-231-635-454; 101-571-462-259-131; 101-597-354-050-512; 103-897-042-300-110; 105-595-185-566-193; 109-079-871-281-328; 115-236-108-351-437; 120-974-286-046-262; 121-343-521-808-788; 125-140-247-124-222; 125-803-684-819-449; 126-452-098-878-109; 126-594-535-567-290; 130-057-480-639-007; 130-436-027-268-877; 133-754-446-702-597; 139-759-040-963-94X; 144-007-214-079-716; 149-824-161-307-640; 151-120-443-482-400; 170-185-768-025-853; 174-791-346-513-801; 197-384-212-360-797,89,true,"CC BY, CC0",gold -053-824-610-694-711,Bibliometric Analysis of Scientific Production in School Physical Education,,2023,journal article,Journal of Sport Pedagogy & Research,,Sociedade Cientifica de Pedagogia do Desporto,,Rick Gomes; Naicha Souza; Alex Crisp,"School physical education is an area of growing academic interest due to its crucial role in the comprehensive development of students. The current study aims to map and analyze the bibliometric indicators of research on school Physical Education. The research was conducted using the SCOPUS and Web of Science databases. The Bibliometrix package in R was used to analyze the bibliometric indicators. A total of 18667 documents involving 30642 authors were identified, published between 1890 and 2023, with an annual growth rate of 4.3%. The studies were published across 3560 journals, with ""Research Quarterly for Exercise and Sports"" being particularly prominent. Network analysis revealed a broad interconnection of research within three main clusters: pedagogy, health promotion, and motivation. In conclusion, research in school physical education encompasses a wide and diverse research network, with an increasing focus on the intersection between pedagogy and health promotion.",9,3,9,15,Production (economics); Mathematics education; Psychology; Economics; Macroeconomics,,,,,,http://dx.doi.org/10.47863/efuc9727,,10.47863/efuc9727,,,0,007-239-193-212-842; 008-194-165-694-135; 011-031-539-072-472; 013-507-404-965-47X; 017-151-725-385-944; 025-699-783-366-219; 025-729-971-186-56X; 034-195-079-989-444; 035-811-347-723-566; 039-105-865-354-024; 043-225-620-316-872; 044-666-608-406-947; 046-992-864-415-70X; 055-905-744-822-835; 061-697-266-666-789; 067-875-295-317-243; 074-063-324-003-236; 096-261-449-126-614; 099-602-796-929-675; 101-920-025-338-15X; 111-049-942-547-934; 122-032-725-127-333,0,false,, -053-848-508-999-638,Mapping the Mindful Balance,2025-01-03,2025,book chapter,Advances in Human Resources Management and Organizational Development,23273372; 23273380,IGI Global,,Shikha Mann; Kalpana Deshmukh; Saurabh Bhattacharya; Sakshi Mann,"This bibliometric analysis, using Scopus data, specifically examines 68 publications obtained through the use of the keywords 'mindfulness' and 'work-life balance' from academic journals in the fields of psychology and business. The investigation leverages complete bibliometric insights by utilizing the bibliometrix package in R, written by Aria and Cuccurullo (2017), and employing data visualization and examination. The software is specifically intended to handle complex bibliographic data and is highly effective in extracting significant information from the dataset. It provides a powerful tool for conducting comprehensive bibliometric analysis, thanks to its wide range of capabilities. This study explores the complex relationships between work-life balance, mental health, and mindfulness in the workplace, going beyond traditional scholarly discourse to reveal significant worldwide consequences. The study reveals a tripartite relationship that has profound consequences for the larger social environment in addition to drawing scholarly attention.",,,449,472,Scopus; Mindfulness; Balance (ability); Data science; Bibliometrics; Visualization; Mental health; Psychology; Computer science; Sociology; Knowledge management; World Wide Web; Political science; Data mining; MEDLINE; Neuroscience; Law; Psychotherapist,,,,,,http://dx.doi.org/10.4018/979-8-3693-2939-9.ch024,,10.4018/979-8-3693-2939-9.ch024,,,0,004-902-628-475-676; 025-367-666-737-892; 027-423-013-331-613; 039-082-448-445-735; 051-647-739-244-271; 116-318-498-739-044; 116-987-963-286-254; 117-798-745-583-131,0,false,, -054-372-345-382-566,Open Science and its role in global scientific collaboration,2025-05-11,2025,journal article,Journal of Posthumanism,26343584; 26343576,Nobel Press Resources,,Luis Fernando Garcés-Giraldo; David Alberto García-Arango; José Alexander Velásquez Ohcoa; Conrado Giraldo Zuluaga; Eduar Antonio Rodríguez-Flores; Marianella Suárez-Pizzarello; Leonardo Fabio Montoya-Guiral,"Open Science has transformed the generation and dissemination of scientific knowledge, promoting transparency and accessibility, the present study evaluates the impact of Open Science on the reproducibility and transparency of research through a mixed-methods approach, the methodology includes a bibliometric analysis using the Bibliometrix software, where 536 articles on Open Science extracted from Scopus were analyzed,  Of these, 30 studies were selected with specific inclusion criteria such as: methodological rigor, empirical and theoretical relevance in the topics of transparency and scientific production. Likewise, a systematic review was carried out according to the PRISMA protocol to identify challenges and opportunities of Open Science in diverse areas, such as space exploration, health research and criminology.",5,5,3178,3205,Open science; Data science; Computer science; Physics; Astronomy,,,,,,http://dx.doi.org/10.63332/joph.v5i5.1714,,10.63332/joph.v5i5.1714,,,0,,0,false,, -054-754-419-605-632,Research trends of biomechanics in scoliosis from 1999 to 2023: a bibliometric analysis.,2024-11-05,2024,journal article,Spine deformity,22121358; 2212134x,Springer Science and Business Media LLC,Netherlands,Peng Dou; Xuan Li; Haobo Jin; Boning Ma; Ming Jin; Yi Xu,,13,2,391,403,Medicine; Biomechanics; Scoliosis; Orthopedic surgery; Bibliometrics; Citation analysis; Library science; Anatomy; Surgery; Citation; Computer science,Adolescent idiopathic scoliosis; Adult spinal deformity; Bibliometric analysis; Biomechanics; Scoliosis,Bibliometrics; Humans; Scoliosis/physiopathology; Biomechanical Phenomena; Biomedical Research/trends,,National Natural Science Foundation of China (No. 82172548); Sun Yat-sen University (20242105),,http://dx.doi.org/10.1007/s43390-024-01000-z,39499450,10.1007/s43390-024-01000-z,,,0,000-837-163-188-736; 001-062-948-560-900; 002-238-323-925-634; 008-392-716-332-892; 008-951-137-273-152; 009-357-375-663-724; 011-454-888-286-588; 013-303-874-151-249; 013-507-404-965-47X; 015-121-757-441-808; 015-774-079-830-633; 015-936-474-143-074; 018-427-195-468-582; 018-803-979-402-668; 019-688-645-827-952; 020-843-946-667-684; 021-673-792-644-240; 022-581-866-094-105; 028-825-551-329-770; 031-371-759-982-837; 031-432-563-918-645; 035-192-769-854-881; 037-815-640-424-494; 038-342-204-407-232; 039-246-618-022-857; 039-303-425-936-538; 041-476-859-805-145; 041-691-827-950-93X; 041-775-504-814-771; 042-144-912-219-192; 044-511-787-870-940; 045-993-333-977-461; 046-706-776-747-587; 048-295-446-537-99X; 048-381-628-344-946; 049-618-998-024-148; 061-945-680-916-851; 062-909-279-998-828; 064-831-167-168-614; 072-856-861-900-730; 076-191-191-183-817; 078-028-862-013-847; 078-442-934-455-761; 081-402-916-369-757; 086-890-851-556-566; 092-710-855-786-939; 096-555-927-360-223; 098-244-691-511-80X; 098-250-558-225-450; 099-474-044-732-219; 101-022-649-325-539; 102-006-757-366-406; 107-523-185-540-305; 116-869-385-160-74X; 118-636-699-030-150; 132-238-597-993-582; 140-707-549-784-670; 153-192-847-793-665; 153-642-862-574-538; 158-017-021-318-992; 180-776-584-426-174,0,false,, -055-039-160-841-057,GEODIVERSITY AND BIODIVERSITY FOR CONCEPTUAL SYNTHESIS,2022-08-17,2022,conference proceedings article,WIT Transactions on Ecology and the Environment,17433541; 1746448x,WIT Press,,GRICELDA HERRERA-FRANCO; JHON CAICEDO-POTOSÍ; PAUL CARRIÓN-MERO,"The earth changes by various physical, chemical, climatic, and geological factors.These processes have allowed for diversity in both geological and biological environments on the planet.Geological diversity allowed life and its diversity in different environments and ecosystems.This study aims to analyse geodiversity and biodiversity using informetric tools to know their relationship and interaction and research trends in this area.The systematic methodology is four steps: (i) topic and information preparation in Scopus and WoS; (ii) data processing in Bibliometrix-RStudio and VOSviewer; (iii) visualisation of results; and (iv) interpretation of results.The results show that geodiversity enabled different ecosystems and life.Therefore, the main conclusion of this study is that biodiversity is on geodiversity, allowing for diverse ecosystems around the world, promoting geo-eco-tourism development under nature conservation criteria.",1,,383,392,Geodiversity; Biodiversity; Computer science; Environmental science; Environmental resource management; Environmental planning; Ecology; Biology,,,,,http://www.witpress.com/Secure/elibrary/papers/SDP22/SDP22032FU1.pdf https://doi.org/10.2495/sdp220321,http://dx.doi.org/10.2495/sdp220321,,10.2495/sdp220321,,,0,,1,true,,bronze -055-093-271-509-660,A quantitative analysis of research trends in flood hazard assessment,2022-11-07,2022,journal article,Stochastic Environmental Research and Risk Assessment,14363240; 14363259,Springer Science and Business Media LLC,Germany,Wei Zhu; Xianbao Zha; Pingping Luo; Shuangtao Wang; Zhe Cao; Jiqiang Lyu; Meimei Zhou; Bin He; Daniel Nover,,37,1,413,428,Flood myth; Flooding (psychology); Hazard; China; Web of science; Computer science; Data science; Regional science; Geography; Political science; MEDLINE; Psychology; Chemistry; Organic chemistry; Archaeology; Law; Psychotherapist,,,,National Key R&D Program of China,https://www.researchsquare.com/article/rs-1521035/latest.pdf https://doi.org/10.21203/rs.3.rs-1521035/v1,http://dx.doi.org/10.1007/s00477-022-02302-2,,10.1007/s00477-022-02302-2,,,0,001-705-875-214-930; 002-331-333-413-268; 008-265-817-104-678; 008-995-700-430-108; 010-739-832-773-638; 013-507-404-965-47X; 013-524-854-219-241; 013-541-969-076-695; 013-570-183-056-345; 014-405-469-186-716; 014-862-348-794-196; 017-549-399-653-690; 017-786-918-382-116; 018-901-345-252-02X; 019-553-178-397-683; 020-769-074-935-123; 025-470-004-027-547; 029-760-309-167-453; 029-997-023-136-390; 034-213-542-026-540; 034-519-362-039-813; 036-432-587-435-332; 037-193-859-119-992; 038-167-027-744-055; 038-564-817-670-627; 040-509-383-905-838; 045-279-744-788-931; 046-992-864-415-70X; 048-125-002-973-844; 049-725-007-684-625; 053-248-433-392-006; 056-064-428-736-612; 056-426-226-149-95X; 056-977-613-370-655; 059-647-577-123-311; 059-790-921-377-778; 061-265-495-851-743; 070-807-866-746-222; 076-194-779-826-653; 082-932-770-522-070; 084-020-052-387-354; 085-300-287-100-525; 092-203-175-294-627; 099-993-498-730-415; 100-578-004-574-981; 101-752-490-869-458; 105-957-186-471-511; 107-353-808-547-134; 132-321-234-754-571; 140-780-741-462-314; 157-724-279-846-676; 164-246-032-911-448; 171-312-182-197-215,24,false,, -055-457-167-412-855,"State of the art of COVID-19 and business, management, and accounting sector. A bibliometrix analysis.",2020-12-10,2020,journal article,International Journal of Business and Management,18338119; 18333850,Canadian Center of Science and Education,,Maura Campra; Paolo Esposito; Valerio Brescia,"COVID-19 caused a global pandemic in 2020 that completely revolutionized our way of life, consequently affecting the research area of business, management and accounting sector. The study by Donthu & Gustafsson (2020) had produced some significant elements on the effect of COVID-19 in the considered study area. Since that time, all states and universities have engaged academics in the search for solutions and future prospects related to COVID-19. In 2020 alone, 48,038 results can be identified on Scopus, of which however only 155 related to the sector under investigation. This research seeks to fill the gap by performing a bibliometric review of 155 business, management and accounting articles considering the effects of COVID-19. The study shows that the effect influenced all research areas of the sector, although only some present bilometric evidence with a global diffusion. Bibliometric analysis confirms the trend and studies introduced by Donthu & Gustafsson (2020). The main studies focus on transport, regulation, and the global economy's effect, considering both international trade and the redefinition of a series of services, including education. The changes in tourism, medical tourism, the business model in food administration, and new technologies related to teaching activities require more in-depth analysis and a major sharing of results.",16,1,35,,Accounting; Business; Tourism; Emerging technologies; State (polity); Medical tourism; Business management; Coronavirus disease 2019 (COVID-19); Business model; Scopus,,,,,https://iris.unisannio.it/handle/20.500.12070/46960 https://www.ccsenet.org/journal/index.php/ijbm/article/view/0/44391 https://www.ccsenet.org/journal/index.php/ijbm/article/download/0/0/44391/46800 https://iris.unito.it/handle/2318/1761027,http://dx.doi.org/10.5539/ijbm.v16n1p35,,10.5539/ijbm.v16n1p35,3111165266,,0,006-281-611-656-124; 007-841-722-859-177; 009-709-278-191-581; 011-863-358-221-40X; 013-507-404-965-47X; 017-750-600-412-958; 026-845-733-807-089; 028-690-885-532-132; 030-446-420-465-248; 030-664-740-033-407; 034-837-265-172-536; 039-422-080-472-10X; 042-167-740-200-381; 044-344-341-213-65X; 045-990-971-350-774; 046-879-011-543-334; 052-643-899-554-453; 057-692-555-442-741; 057-878-152-499-108; 064-883-665-513-227; 065-088-963-343-469; 065-108-368-829-080; 066-330-466-552-066; 070-658-632-342-034; 077-350-813-191-646; 099-259-072-722-139; 113-200-990-664-897; 121-669-650-467-684; 124-931-561-664-571; 164-222-465-980-629; 197-093-106-836-325,19,true,cc-by,gold -055-718-516-788-045,"Scopus Data For Bibliometrix Analysisi with Keyword ""Marketing performance""",2023-01-01,2023,dataset,Figshare,,,,resanti lestari; Syahyuti yuti; irwanda wisnu wardhana; dyah setyawati; fatmasari endayani,"Scopus Data with keyword ""Marketing Performance"" Year 1959-2023, Acess at Januari 27 2023 at 14.31 PM",,,,,Scopus; Information retrieval; Keyword search; Computer science; World Wide Web; Business; Data science; Chemistry; MEDLINE; Biochemistry,,,,,https://figshare.com/articles/dataset/Scopus_Data_For_Bibliometrix_Analysisi_with_Keyword_Marketing_performance_/22085468,http://dx.doi.org/10.6084/m9.figshare.22085468,,10.6084/m9.figshare.22085468,,,0,,0,true,cc-by,gold -055-724-568-357-66X,Material selection in the construction industry: a systematic literature review on multi-criteria decision making,2025-01-21,2025,journal article,Environment Systems and Decisions,21945403; 21945411,Springer Science and Business Media LLC,United States,Asad Ur Rehman Bajwa; Chandana Siriwardana; Wajiha Shahzad; Muhammad Ahmad Naeem,"Abstract; Material choice is critical for ensuring sustainability in the construction industry. Higher carbon embodiment materials contribute towards greenhouse gas emissions and global warming. Decisions on sustainable material selection depend on multiple criteria and variables, thus creating a difficulty to determine the best choice. Multi-Criteria Decision Making (MCDM) techniques have the potential to address this challenge. However, there is limited data that reviews MCDM in choosing building and construction materials. This study aims to review the MCDM methods employed in the sustainable selection of building materials within the construction industry. This systematic literature review (SLR) incorporates meta-analysis and thematic mapping through applying “PRISMA framework” and “Bibliometrix”, respectively. This study explored and analysed the records published from 2010 to 2023. This work identified the critical steps for addressing decision problems in building material selection: Establishing criteria, ranking the hierarchy, comparing the selection criteria, and enabling consistency indices. Moreover, one of the most used MCDM methods, i.e. Analytical Hierarchy Process (AHP) was particularly found particularly useful for the selection criteria and weight assignment of variables regarding the waste, recycled, and composite materials. The involvement of several criteria and alternatives raised the complexity of decision problems, leading to the use of Hybrid MCDM. Hybrid MCDM techniques possess the capacity guide informed decisions for the sustainable material selection in the construction industry.",45,1,,,Selection (genetic algorithm); Management science; Systematic review; Computer science; Engineering; Construction engineering; Artificial intelligence; Political science; MEDLINE; Law,,,,Massey University,,http://dx.doi.org/10.1007/s10669-025-10001-w,,10.1007/s10669-025-10001-w,,,0,002-771-578-589-359; 003-304-842-347-011; 005-447-603-604-835; 007-382-025-876-158; 009-139-024-871-665; 010-059-133-602-451; 011-149-843-427-905; 012-654-536-521-436; 012-657-002-620-37X; 013-507-404-965-47X; 015-475-707-939-796; 017-037-873-028-915; 017-139-727-020-162; 018-017-957-533-01X; 032-948-382-698-608; 033-696-935-061-542; 042-128-335-052-088; 042-595-808-700-368; 043-226-072-946-498; 047-525-456-711-810; 056-650-951-337-036; 068-879-446-887-484; 069-716-145-279-530; 074-773-727-053-832; 076-498-170-063-038; 078-216-190-387-309; 084-249-962-919-116; 084-326-950-068-154; 086-055-758-927-124; 086-704-882-591-784; 087-522-406-031-654; 088-951-486-768-315; 092-590-365-119-865; 093-372-418-686-435; 106-406-813-004-839; 112-284-467-553-492; 115-455-447-638-184; 117-764-375-151-44X; 127-485-475-331-342; 130-019-596-746-800; 132-607-356-544-592; 132-618-302-950-732; 132-894-823-425-993; 133-868-384-973-601; 134-464-945-370-831; 135-068-947-560-067; 139-192-290-278-932; 139-836-488-800-248; 143-068-406-755-996; 151-386-782-776-25X; 157-025-490-216-394; 157-167-296-086-294; 158-626-070-499-893; 167-229-718-028-38X; 167-964-282-262-327; 185-040-234-823-647; 185-371-210-709-395; 197-799-657-099-784; 198-020-870-659-167,3,true,cc-by,hybrid -055-986-821-352-177,Family firms management and performance: A literature review using R Bibliometrix,,2020,,,,,,André Coelho Rui Silva,,,,26,,,,,,,https://dialnet.unirioja.es/servlet/articulo?codigo=7724351,https://dialnet.unirioja.es/servlet/articulo?codigo=7724351,,,3173086516,,0,,0,false,, -056-534-300-734-080,DONATION TRANSPARENCY THROUGH BLOCKCHAIN TECHNOLOGY: A BIBLIOMETRIC ANALYSIS,2024-11-27,2024,journal article,iBAF e-Proceedings,2948460x,Universiti Sains Islam Malaysia,,Nur Aqilah Hazirah Mohd Anim; Norfhadzilahwati Rahim,"This bibliometric study explores blockchain technology in the donation ecosystem using 44 scholarly publications from SCOPUS (2016-2024). Employing Biblioshiny from the Bibliometrix R package, the study identifies patterns and research gaps. Significant findings highlight the role of smart contracts and cryptocurrency in fostering transparency and security in donations. Additionally, cross-disciplinary discussions are encouraged to integrate blockchain into the donation system effectively. The study enhances understanding and offers strategic insights for future research.",11,1,445,450,Blockchain; Transparency (behavior); Donation; Computer science; Computer security; Political science; Law,,,,,https://epibaf.usim.edu.my/index.php/eproceeding/article/download/38/38 https://doi.org/10.33102/82gb3a38,http://dx.doi.org/10.33102/82gb3a38,,10.33102/82gb3a38,,,0,,0,true,,bronze -056-794-311-258-981,Tinjauan Literatur Sistematis dan Analisis Bibliometrik Penelitian Kerentanan Airtanah di Indonesia (2013-2021),2022-10-01,2022,journal article,Jurnal Ilmiah Geologi PANGEA,2356024x; 2987100x,Universitas Pembangunan Nasional Veteran Yogyakarta,,Adam Raka Ekasara; Nuha Amiratul Afifah; Riska Aprilia Triyadi; Thema Arrisaldi; Daniel Radityo; Hasan Tri Atmojo,"Abstrak - Kebutuhan masyarakat terkait dengan airtanah semakin meningkat. Penilaian kerentanan airtanah menjadi salah satu cara untuk melindungi sumber daya airtanah agar tidak tercemar. Penelitian ini bertujuan untuk melakukan tinjauan literatur sistematis dan analisis bibliometrik untuk penelitian kerentanan airtanah di Indonesia menggunakan basis data Scopus. Parameter yang dianalisis berupa jumlah terbitan, sumber jurnal/prosiding, kata kunci dan jumlah kutipan. Dari hasil pencarian didapatkan 26 artikel dari 74 penulis pada rentang 2013-2021. Kata kunci populer yang muncul pada penelitian diantaranya groundwater pollution, groundwater vulnerability, groundwater resources, aquifers, dan groundwater. Pengolahan data dan visualisasi menggunakan aplikasi Bibliometrix dan VOSviewer. Dari hasil analisis disusun peta tematik yang menggambarkan 4 kuadran berdasarkan tingkat kepadatan dan tingkat sentralitas. Peta tematik ini diharapkan bisa menjadi acuan untuk penelitian kerentanan airtanah di Indonesia.  Kata kunci: airtanah, analisis bibliometrik, Bibliometrix VOSviewerAbstract - The needs of the community related to groundwater are increasing. Assessing groundwater vulnerability is one way to protect groundwater resources from being polluted. This study aims to review systematic literature and bibliometric analysis for groundwater vulnerability research in Indonesia using the Scopus database. The parameters were analyzed through several publications, journals/proceedings, keywords and total citations. The search results found 26 articles from 74 authors in the range 2013-2021. Popular keywords that emerged in research include groundwater pollution, groundwater vulnerability, groundwater resources, aquifers, and groundwater. Data processing and visualization using the bibliometric and VOSviewer applications. The results of the analysis compiled a thematic map that describes 4 quadrants based on density and centrality levels. This thematic map is expected to be a reference for groundwater vulnerability research in Indonesia.Keywords: groundwater, bibliometric analysis, Bibliometrix VOSviewer",9,1sp,8,8,Groundwater; Thematic map; Environmental science; Geography; Humanities; Water resource management; Hydrology (agriculture); Forestry; Cartography; Engineering; Art; Geotechnical engineering,,,,,http://jurnal.upnyk.ac.id/index.php/jig/article/download/9404/5228 https://doi.org/10.31315/jigp.v9i1sp.9404,http://dx.doi.org/10.31315/jigp.v9i1sp.9404,,10.31315/jigp.v9i1sp.9404,,,0,,0,true,cc-by-nc-sa,hybrid -056-881-376-482-349,"Uncovering the organizational, environmental, and socio-economic sustainability of digitization: evidence from existing research",2023-03-15,2023,journal article,Review of Managerial Science,18636683; 18636691,Springer Science and Business Media LLC,Germany,Ritika Chopra; Anirudh Agrawal; Gagan Deep Sharma; Andreas Kallmuenzer; Laszlo Vasa,"Sustainability and digitization have become significant parts of the global economy in recent years. Numerous studies examine the relationship between sustainability's environmental concerns and digitization. In contrast, few studies address the topic of organizational, environmental, and socioeconomic sustainability's integration with digital technologies. This paper intends to fill this void by conducting a bibliometric analysis of the relevant literature. Along with descriptive insights, we explain the area's social, intellectual, and conceptual structures, its evolution, and its future agenda. The article discusses how technology adaption improves individuals' and companies' efficacy, performance, and profitability. Second, the article suggests more funding to produce environmentally friendly, greener technologies that can promote inclusive economic models and spur sustainable growth. Third, the article explores explore technology's social and ethical implications, highlighting the need to consider gender, race, ethnicity, and location when digitizing the world. By drawing on extant evidence and integrating findings, the research concludes by providing a fresh academic and policy contribution to the twin fields of digitalization and sustainability.",18,2,685,709,Sustainability; Digitization; Socioeconomic status; Extant taxon; Sociology; Knowledge management; Engineering; Ecology; Computer science; Population; Telecommunications; Demography; Evolutionary biology; Biology,,,,,https://link.springer.com/content/pdf/10.1007/s11846-023-00637-w.pdf https://doi.org/10.1007/s11846-023-00637-w,http://dx.doi.org/10.1007/s11846-023-00637-w,,10.1007/s11846-023-00637-w,,,0,000-339-483-466-289; 000-380-618-467-647; 000-620-668-708-795; 004-431-445-128-075; 004-837-032-534-411; 009-262-373-122-623; 010-065-762-504-134; 012-128-137-288-200; 012-628-642-478-532; 013-507-404-965-47X; 017-750-600-412-958; 020-694-023-700-531; 020-821-233-783-792; 025-267-211-964-783; 028-782-255-031-323; 029-346-157-246-174; 030-671-248-846-321; 032-459-097-996-772; 032-471-004-574-303; 034-034-822-103-578; 037-208-656-033-733; 037-921-141-323-09X; 040-778-348-220-273; 041-223-926-956-248; 044-788-977-218-867; 047-580-627-635-421; 048-199-286-862-872; 049-113-968-676-280; 050-989-847-859-074; 051-518-139-924-045; 051-851-761-421-930; 055-372-469-607-532; 057-465-409-908-291; 061-895-842-101-629; 064-025-248-874-645; 074-504-010-794-945; 080-294-980-130-298; 081-278-486-885-35X; 087-547-944-111-96X; 095-822-180-242-954; 100-603-573-401-580; 101-752-490-869-458; 104-211-237-712-382; 104-312-442-530-257; 104-805-536-540-873; 105-816-034-633-80X; 107-262-715-167-286; 109-338-800-631-814; 114-496-968-216-010; 130-291-776-570-403; 134-185-052-339-19X; 136-473-108-195-172; 142-699-387-067-243; 143-107-322-536-058; 146-208-436-691-12X; 152-491-006-023-766; 156-192-014-728-817; 196-464-340-982-471,20,true,,bronze -056-882-223-504-003,"Global trends in the application of virtual reality for people with autism spectrum disorders: conceptual, intellectual and the social structure of scientific production",2021-09-08,2021,journal article,Journal of Computers in Education,21979987; 21979995,Springer Science and Business Media LLC,,G. Lorenzo; N. Newbutt; A. Lorenzo-Lledó,,9,2,225,260,,,,,,,http://dx.doi.org/10.1007/s40692-021-00202-y,,10.1007/s40692-021-00202-y,,,0,000-823-953-414-059; 003-601-828-824-230; 003-868-747-830-164; 004-972-241-206-942; 005-599-948-063-74X; 005-611-357-705-527; 007-680-337-429-563; 008-022-972-738-375; 010-065-762-504-134; 010-273-663-103-016; 012-776-103-340-352; 013-507-404-965-47X; 013-524-854-219-241; 015-080-866-622-167; 017-750-600-412-958; 018-814-147-267-436; 019-041-510-068-218; 019-414-184-696-09X; 019-731-115-116-919; 021-042-063-586-545; 022-679-650-709-524; 023-192-387-344-91X; 024-501-464-929-077; 028-920-949-253-206; 030-275-029-564-880; 030-647-174-824-057; 031-096-825-110-831; 033-103-723-864-400; 033-104-363-919-280; 033-655-836-743-352; 034-565-665-655-178; 035-036-086-363-069; 035-166-111-974-845; 042-373-598-659-606; 044-151-611-794-538; 044-532-677-871-275; 045-694-629-324-486; 046-066-727-181-940; 046-992-864-415-70X; 047-192-946-816-946; 050-664-965-270-417; 053-786-467-071-25X; 055-069-593-800-960; 055-749-872-948-852; 057-280-673-282-40X; 057-803-697-074-453; 067-899-894-243-588; 070-390-729-944-520; 070-414-374-509-637; 071-267-990-907-646; 071-549-036-634-43X; 073-663-211-670-297; 079-983-852-096-070; 081-020-199-387-771; 090-499-359-816-154; 096-806-131-656-233; 104-919-753-218-202; 106-483-971-474-931; 106-645-639-889-106; 108-605-848-877-474; 117-094-720-234-570; 130-964-505-994-38X; 131-423-542-523-282; 139-079-722-348-451; 144-042-338-780-241; 158-860-409-543-132; 160-358-354-726-713; 165-312-901-216-084; 169-792-599-321-772; 176-440-018-222-886; 177-882-177-384-49X,16,false,, -056-892-750-627-127,Advances and Challenges of a Circular Economy (CE) in Agriculture in Ibero-America: A Bibliometric Perspective,2024-11-06,2024,preprint,,,MDPI AG,,Mercedes Gaitan Angulo; Maria Teresa Batista; Melva Inés Gómez Caicedo,"The study presented below establishes the progress and challenges of a Circular Economy (CE) in agriculture in Ibero-America. To this end, a documentary review was carried out to conceptualise the characteristics of CE and the way in which it has been implemented in Ibero-American countries such as Colombia, Brazil, Chile, Venezuela, Costa Rica, Spain and Portugal. Additionally, a bibliometric study was carried out, starting from the &quot;Scopus&quot; and &quot;Wos&quot; databases, which facilitates the identification of the frequency of writings, number of publications, topics related to CE, key words, authors, among other criteria that are fundamental for recognising the importance in the academic and business spheres. This study uses different statistical programmes such as R-tool, R-Package, Bibliometrix, VOSviewer and Biblioshiny. The findings show a growing trend towards the analysis of sustainability and CE processes in agriculture.",,,,,Perspective (graphical); Agriculture; Regional science; Circular economy; Geography; Agricultural economics; Economic geography; Economy; Political science; Economics; Archaeology; Computer science; Biology; Ecology; Artificial intelligence,,,,,,http://dx.doi.org/10.20944/preprints202411.0454.v1,,10.20944/preprints202411.0454.v1,,,0,,1,true,,green -056-992-598-201-495,Prospective study on the electrochemical remediation as an alternative to treat heavy metals in solid waste landfills,2024-10-29,2024,journal article,Cogent Engineering,23311916,Informa UK Limited,United Kingdom,Luis Carlos Caicedo Rosero; José de Jesús Agustín Flores Cuautle,"In this work, the feasibility of using electrochemical remediation for treating municipal solid waste is explored. The viability of electrokinetic remediation is investigated prospectively to identify the electrochemical technology that can be applied to soil remediation using scientometrics, bibliometrics, and infometrics techniques. The study relies on Population, Intervention, Comparison, Outcomes, Context analysis to determine the research question, and Bibliometrix software helps build a theoretical background to search for solutions to soil contamination problems. Because electrokinetic remediation employs a significant amount of electrical energy, it is usually discarded as an applicable technique. However, this work emphasizes the studies where the technique works even in low-power situations. Thus, it can be said that this method serves as a backup for municipal soil waste landfill (MSWL) remediation in cases where none exists.",11,1,,,Environmental remediation; Waste management; Municipal solid waste; Heavy metals; Environmental science; Waste treatment; Engineering; Contamination; Environmental chemistry; Chemistry; Ecology; Biology,,,,,,http://dx.doi.org/10.1080/23311916.2024.2419142,,10.1080/23311916.2024.2419142,,,0,000-899-845-526-580; 003-160-521-770-281; 003-709-973-346-145; 008-081-369-922-485; 008-082-121-223-183; 009-688-278-022-26X; 011-496-889-931-29X; 013-507-404-965-47X; 014-084-918-465-012; 014-377-914-591-512; 014-576-846-991-136; 015-085-720-803-152; 015-867-552-686-204; 016-614-760-537-749; 020-512-014-795-882; 021-135-602-837-781; 021-290-340-484-006; 021-308-193-565-414; 021-683-499-356-580; 023-184-324-163-740; 023-217-597-565-428; 027-862-237-264-055; 032-945-295-813-168; 035-481-872-223-835; 036-698-145-956-673; 037-043-728-539-766; 037-789-881-541-492; 041-643-509-658-005; 043-158-557-436-689; 043-428-875-106-316; 044-177-414-187-494; 045-450-124-805-46X; 045-908-651-085-064; 046-156-668-681-61X; 051-273-412-535-313; 052-314-285-758-411; 053-768-168-301-546; 055-208-368-306-277; 058-165-668-860-810; 059-778-687-265-572; 059-842-905-327-49X; 064-205-728-988-439; 065-534-789-027-539; 067-705-951-391-547; 067-713-328-113-609; 070-079-410-232-087; 070-708-457-505-15X; 072-143-566-858-605; 077-466-630-284-887; 078-195-750-522-661; 078-577-335-203-632; 082-192-109-575-136; 082-734-423-157-462; 085-850-572-498-997; 086-331-288-209-969; 090-066-199-986-280; 090-739-301-780-662; 095-316-639-757-176; 097-817-506-687-723; 101-568-177-231-183; 103-429-008-716-22X; 110-465-276-204-003; 110-941-260-412-152; 111-151-895-876-954; 112-170-969-655-899; 112-668-159-146-505; 112-679-829-972-413; 116-036-985-827-652; 117-785-431-142-939; 124-976-617-196-797; 127-164-922-129-182; 128-861-419-531-780; 133-666-185-043-262; 142-115-139-482-948; 144-585-886-862-353; 151-055-374-763-699; 159-763-730-673-867; 179-664-589-944-286; 189-687-469-245-792,0,true,cc-by,gold -057-654-040-328-176,The Research Output of Bibliometrics using Bibliometrix R Package and VOS Viewer,2021-10-01,2021,journal article,"Shanlax International Journal of Arts, Science and Humanities",25820397; 2321788x,Shanlax International Journals,,L Radha; J Arumugam,"Bibliometrics is one of the statistical methods to analyze the research output of books, articles, and other scientific publications. This paper attempts to study the three types of Bibliometric indicators such as quantity, quality, and structural indicators. This study pertains to the information on the research growth of Bibliometric study, especially in the subject category of Library and Information Science published in Web of Science Database. This paper presents the findings of a Bibliometric study, targeting five year period (2014–2018), with the aim of identifying emerging research directions, the top-20 institutions, coupling, and collaboration by applying VOS viewer and Biblioshiny for bibliometric tools.",9,2,44,49,Computer graphics (images); Bibliometrics; R package; Computer science,,,,,https://shanlaxjournals.in/journals/index.php/sijash/article/download/4197/3496,http://dx.doi.org/10.34293/sijash.v9i2.4197,,10.34293/sijash.v9i2.4197,3205493251,,0,,19,true,cc-by-sa,gold -057-666-727-865-371,Islamic Finance in Africa: An Analysis Using Bibliometrix R-Tool,2025-01-08,2025,journal article,Journal of Islamic Economics Literatures,27754251,Sharia Economic Applied Research and Training (SMART) Insight,,Muniem Adam,"Islamic finance in Africa is a growing sector, offering financial services that adhere to Islamic principles (Shariah), including the prohibition of interest (riba) and speculative activities (gharar). This industry plays an essential role in addressing the continent's development challenges by providing innovative financial solutions that promote economic inclusiveness and ethical practices. This study quantitatively analyzes the literature on Islamic finance in Africa spanning from 1992 to 2024 using articles indexed in  Scopus. It adopts a combination of bibliometric and content analysis approaches. The findings indicate Hasan M. Kabir as the most prominent author, the United Kingdom with the most relevant quantity of authors, and Africa as the prevailing keyword. Addressing the absence of prior bibliometric studies, this inaugural research covers: (1) Islamic finance and African development (2) Islamic banking drives investment in Africa and (3) Islamic finance in East Africa.",5,2,,,Islamic finance; Islam; Scopus; Investment (military); Financial services; Islamic banking; Islamic economics; Political science; Accounting; Finance; Business; Economics; Law; Geography; Archaeology; MEDLINE; Politics,,,,,,http://dx.doi.org/10.58968/jiel.v5i2.579,,10.58968/jiel.v5i2.579,,,0,,0,false,, -057-898-626-686-617,Unearthing the landscape: a bibliometric exploration of hairy root culture research over the past 41 years,2025-01-13,2025,journal article,In Vitro Cellular & Developmental Biology - Plant,10545476; 14752689,Springer Science and Business Media LLC,United Kingdom,Shivani Negi; Pooja Singh; Balwant Rawat; Avinash Sharma; Janhvi Mishra Rawat; Prabhakar Semwal,,61,1,1,24,Root (linguistics); History; Cultural landscape; Geography; Archaeology; Anthropology; Sociology; Linguistics; Philosophy,,,,,,http://dx.doi.org/10.1007/s11627-024-10488-z,,10.1007/s11627-024-10488-z,,,0,001-161-305-978-901; 001-232-291-704-349; 002-407-980-909-997; 002-763-065-549-095; 002-964-172-968-077; 003-468-470-261-620; 003-696-572-532-190; 004-339-989-627-508; 004-780-618-190-199; 005-620-433-441-135; 006-699-332-263-887; 008-330-206-283-88X; 008-891-442-202-332; 009-813-524-081-960; 010-408-841-636-030; 010-707-476-660-971; 013-507-404-965-47X; 013-621-707-681-254; 013-704-352-093-819; 016-242-322-154-671; 020-448-378-647-190; 020-873-734-908-914; 020-896-680-681-84X; 021-162-552-495-843; 021-943-972-880-758; 023-825-824-813-268; 024-745-978-209-991; 025-168-992-480-189; 026-870-979-166-01X; 027-910-988-302-079; 028-001-644-947-779; 028-236-976-859-309; 028-563-267-655-950; 030-116-704-627-796; 030-304-329-274-981; 033-399-918-393-800; 034-205-781-410-961; 034-473-621-165-785; 035-197-008-247-035; 035-612-228-053-764; 036-149-162-481-591; 037-467-743-781-39X; 037-790-069-431-928; 040-237-768-743-861; 040-461-845-270-620; 041-259-791-582-895; 042-057-201-916-279; 043-455-624-838-495; 044-089-800-428-129; 045-165-766-701-774; 045-898-608-512-896; 046-992-864-415-70X; 047-210-029-903-985; 047-288-965-877-150; 047-930-701-803-073; 049-759-737-439-803; 049-943-966-414-570; 050-487-023-709-348; 053-981-143-391-269; 055-186-545-016-656; 058-088-454-256-750; 058-569-876-558-30X; 061-440-926-094-656; 062-127-948-622-814; 062-589-104-188-348; 062-676-210-088-063; 066-892-347-853-274; 070-549-083-354-899; 071-844-076-782-05X; 071-878-836-294-733; 073-840-780-495-825; 076-498-170-063-038; 076-858-990-023-441; 079-530-920-504-805; 080-370-298-188-608; 081-350-513-104-779; 081-459-999-654-402; 083-097-104-274-79X; 089-173-228-740-65X; 089-510-196-177-026; 089-919-845-099-579; 090-195-126-750-761; 094-268-415-631-996; 095-683-830-753-995; 099-124-511-080-935; 099-965-079-002-546; 101-758-338-174-448; 102-318-601-614-162; 102-888-046-879-827; 103-704-489-392-126; 104-029-211-445-027; 105-064-784-250-518; 108-080-577-177-863; 116-272-738-599-28X; 118-565-370-836-997; 120-759-028-264-839; 123-736-664-708-928; 126-445-546-317-888; 126-641-845-658-090; 127-068-491-604-032; 134-561-071-709-711; 140-407-441-343-377; 151-764-662-014-061; 154-383-825-047-360; 155-877-518-423-924; 156-325-978-899-801; 157-267-099-952-518; 173-752-263-001-394; 180-779-015-803-64X; 184-780-638-635-05X; 189-499-113-998-808; 196-499-014-529-76X,1,false,, -058-061-633-367-173,Trends on Gastrotricha research: a bibliometric analysis,2024-04-16,2024,journal article,Biologia,13369563; 00063088,Springer Science and Business Media LLC,Germany,Thiago Quintão Araújo; Axell Kou Minowa; André R. S. Garraffoni,,79,7,2095,2107,Geography,,,,Fundação de Amparo à Pesquisa do Estado de São Paulo; Fundação de Amparo à Pesquisa do Estado de São Paulo; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,,http://dx.doi.org/10.1007/s11756-024-01686-6,,10.1007/s11756-024-01686-6,,,0,002-237-241-736-683; 002-916-415-884-091; 003-368-480-652-547; 004-259-782-708-773; 011-135-999-601-511; 012-063-111-838-097; 012-502-400-824-574; 013-507-404-965-47X; 013-544-973-984-577; 013-882-222-812-696; 014-236-376-659-76X; 016-758-143-135-35X; 017-839-472-387-92X; 018-156-069-759-694; 020-665-583-874-158; 021-238-345-054-330; 025-131-597-207-474; 026-752-814-949-764; 028-481-856-753-269; 028-862-980-214-94X; 029-659-685-414-79X; 030-184-036-846-700; 031-463-157-865-519; 034-261-566-147-845; 034-570-355-581-608; 038-330-108-695-344; 039-365-536-623-490; 039-952-010-698-945; 045-500-712-665-523; 047-485-112-115-368; 047-864-759-001-054; 048-772-786-780-418; 061-217-634-534-275; 064-761-536-125-759; 066-989-807-648-53X; 073-826-021-036-280; 075-511-335-569-035; 075-867-661-171-53X; 077-774-617-483-552; 078-897-564-057-66X; 088-503-579-305-134; 090-544-928-334-236; 090-745-730-153-764; 091-366-465-556-568; 092-725-207-354-689; 095-009-910-049-784; 095-697-724-678-597; 100-862-411-425-084; 101-648-584-840-699; 103-169-304-214-023; 103-979-775-528-453; 104-418-546-053-454; 107-223-549-258-198; 107-354-713-132-352; 109-397-569-789-044; 110-134-342-994-482; 111-447-126-506-097; 113-928-515-648-902; 116-012-233-806-158; 117-820-978-222-968; 122-617-123-897-561; 134-205-455-837-500; 186-624-831-982-035; 187-238-660-127-229; 193-988-417-664-606,3,false,, -058-430-800-761-671,Exploring trends and developments in cholesteatoma research: a bibliometric analysis.,2024-05-29,2024,journal article,European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,14344726; 09374477,Springer Science and Business Media LLC,Germany,Burak Numan Uğurlu; Gülay Aktar Uğurlu,,281,10,5199,5210,Cholesteatoma; Bibliometrics; Data science; Library science; Medicine; Computer science; Radiology,Bibliometric analysis; Cholesteatoma; Research trends; Scientometric analysis,"Humans; Bibliometrics; Biomedical Research/trends; Cholesteatoma, Middle Ear/surgery; Periodicals as Topic/statistics & numerical data",,,,http://dx.doi.org/10.1007/s00405-024-08749-z,38809268,10.1007/s00405-024-08749-z,,,0,002-052-422-936-00X; 004-644-964-039-890; 006-593-902-396-126; 007-642-769-575-014; 010-170-690-665-258; 012-689-281-955-32X; 013-507-404-965-47X; 014-014-018-682-499; 015-998-681-250-669; 020-329-327-294-637; 020-411-087-670-631; 021-187-404-778-375; 032-347-334-372-992; 036-734-043-704-040; 037-728-579-081-019; 041-010-210-179-720; 041-979-514-068-738; 050-042-789-625-365; 050-606-352-249-281; 052-553-337-503-962; 058-743-456-853-741; 061-682-696-726-727; 072-498-326-485-849; 078-707-801-061-647; 080-111-224-173-087; 089-210-723-826-40X; 089-885-322-420-092; 091-845-520-714-652; 095-848-928-759-431; 109-086-932-636-90X; 142-133-820-677-243; 143-312-561-205-400,5,false,, -058-496-486-219-80X,Beatriz Milz: Conhecendo o pacote bibliometrix,2021-03-07,2021,,,,,,Beatriz Milz,,,,,,Art,,,,,,,,,3134851661,,0,013-507-404-965-47X,0,false,, -058-599-545-559-428,Investigating the Research Path from the Past to the Future of the Common Field of Nanotechnology and Fungi: A Bibliometric Study,2024-05-15,2024,journal article,Nano,17932920; 17937094,World Scientific Pub Co Pte Ltd,United States,Homa Hamayeli; Ali Mohammadi; Nader Ale Ebrahim," Nanoparticles have been considered in many fields such as medicine and industry due to their very small size and their special physicochemical properties. Biosynthesis of nanoparticles has advantages over other methods. This paper examines the bibliography of the relationship between nanotechnology and fungi from 1985 to 2021. Data were collected from three databases consisting of Web of Science, Scopus, and Dimensions. The number and type of documents were examined and then the analysis was continued using VOSviewer and Bibliometrix-package on the documents of the Scopus database. Analysis of 1203 documents from this database showed an upward trend in the publication in recent years. The term “Fungi” was also identified as the keyword index and India as the country with the most published documents. Future research is likely to be on using modern techniques in the study of nanoparticles as well as focusing on other genera of fungi. ",19,6,,,Nanotechnology; Materials science; Field (mathematics); Path (computing); Engineering physics; Engineering; Computer science; Mathematics; Pure mathematics; Programming language,,,,,,http://dx.doi.org/10.1142/s1793292024300032,,10.1142/s1793292024300032,,,0,000-081-370-016-93X; 000-977-783-846-917; 002-052-422-936-00X; 002-287-601-642-898; 003-771-620-926-352; 006-543-098-607-547; 007-394-481-724-834; 012-508-678-289-745; 012-982-389-667-12X; 013-507-404-965-47X; 016-593-987-913-577; 020-892-596-255-17X; 023-631-927-302-879; 024-182-081-664-23X; 025-470-225-260-326; 025-750-840-170-417; 026-967-620-372-504; 032-499-243-866-017; 033-189-518-912-864; 036-494-499-020-819; 037-879-025-411-328; 038-127-102-578-91X; 038-423-757-608-282; 038-961-396-299-856; 042-493-730-723-553; 043-764-065-366-434; 052-900-344-372-394; 057-204-651-721-577; 057-895-170-408-542; 059-145-612-580-164; 061-174-610-390-038; 062-176-832-021-946; 066-981-961-605-996; 067-186-151-153-389; 069-698-129-356-384; 070-708-457-505-15X; 072-378-406-896-684; 073-548-790-294-826; 073-586-259-746-32X; 074-614-943-459-564; 081-770-363-464-066; 081-770-499-092-329; 082-802-826-888-157; 087-604-255-577-623; 087-840-018-492-129; 089-863-932-573-603; 094-919-294-481-448; 095-224-202-591-937; 095-946-963-216-327; 102-997-173-530-743; 106-883-191-593-019; 110-239-833-345-189; 111-628-063-171-463; 121-000-827-597-376; 130-344-391-132-740; 130-498-522-295-358; 136-389-535-500-934; 140-540-662-347-18X; 151-970-074-383-642; 174-814-422-535-391; 175-191-907-949-806,0,false,, -058-949-585-837-370,A Scoping Review Investigating the Use of Outcome-based Models to Improve Healthcare Outcomes and Reduce Healthcare Spending,2022-12-07,2022,conference proceedings article,2022 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM),,IEEE,,G. T. Chidavaenzi; S. S. Grobbelaar; F. Salie,"Outcome-based models (OBMs) guarantee quality outcomes through pay-for-performance mechanisms. This article considers OBMs to reduce healthcare spending and improve healthcare outputs by conducting a scoping review (SR) of literature surrounding this topic. The set of articles considered was visualised and analysed through Bibliometrix and full-text reading. Key findings from the review include the growth of the topic in the last five years and the need for further research on contract agreements, cost/risk-sharing, measurement of outcomes, types of OBMs, and guiding conceptual frameworks.",,,1219,1223,Health care; Outcome (game theory); Key (lock); Set (abstract data type); Quality (philosophy); Reading (process); Computer science; Knowledge management; Business; Economics; Computer security; Political science; Microeconomics; Philosophy; Epistemology; Law; Programming language; Economic growth,,,,,,http://dx.doi.org/10.1109/ieem55944.2022.9989779,,10.1109/ieem55944.2022.9989779,,,0,001-089-258-374-836; 006-462-786-195-801; 013-303-277-111-046; 013-507-404-965-47X; 017-802-066-801-794; 029-997-349-513-088; 032-786-263-236-719; 033-037-623-679-619; 035-691-920-009-856; 037-260-767-491-700; 038-384-842-276-762; 038-682-026-879-149; 041-024-140-500-749; 048-315-904-750-508; 049-391-379-302-694; 053-533-938-817-148; 058-047-344-222-268; 065-084-220-037-93X; 065-910-519-559-101; 071-649-803-697-801; 071-775-788-133-123; 071-919-526-413-395; 075-930-796-241-346; 076-498-170-063-038; 085-389-708-711-580; 086-804-169-394-45X; 103-543-337-972-928; 129-944-963-467-583; 162-898-089-243-12X,1,false,, -059-094-752-940-144,Preprocesamiento de publicaciones acerca de indentidad digital descentralizada y autgobernada.,2022-01-01,2022,dataset,Figshare,,,,Roberto Pava,Referencias en formato bibtex obtenidas de las bases de datos Scopus y WoS. Preprocesamiento con el paquete bibliometrix,,,,,Philosophy,,,,,https://figshare.com/articles/dataset/Referencias_sobre_SSI_obtenidas_en_formato_bibtex/19579492,http://dx.doi.org/10.6084/m9.figshare.19579492,,10.6084/m9.figshare.19579492,,,0,,0,true,cc-by,gold -059-329-415-801-374,"Green finance development and its origin, motives, and barriers: an exploratory study",2025-01-16,2025,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Die Hu; Christopher Gan,"Abstract; As global awareness of sustainability significance intensifies, green finance has become a focal point. In response to this trend, our study extensively examines the evolution of green finance, using exploratory methodologies to produce insightful observations. We perform an all-inclusive bibliometric analysis of literature regarding green finance to reveal significant trends and critical contributors to the domain. Further, we explore the historical evolution of green finance, analyzing its fundamental principles, examining the driving factors and obstacles, and forecasting future directions. We attempt to offer a clearer insight into green finance, facilitating decision-making by scholars, industry professionals, and policymakers.",,,,,Sustainable development; Business; Finance; Natural resource economics; Economics; Political science; Law,,,,Lincoln University,,http://dx.doi.org/10.1007/s10668-024-05570-w,,10.1007/s10668-024-05570-w,,,0,001-305-959-885-800; 001-713-316-819-538; 015-144-463-612-650; 015-301-025-048-398; 018-214-354-135-429; 018-525-806-168-79X; 022-669-279-471-793; 024-225-928-399-708; 024-345-505-333-017; 024-800-979-249-61X; 031-470-083-415-448; 032-841-038-580-07X; 033-007-235-150-53X; 036-412-583-650-731; 038-199-165-289-19X; 039-906-827-771-783; 047-655-271-165-820; 049-733-428-118-410; 054-089-775-416-902; 055-448-824-518-664; 057-515-048-274-248; 059-298-341-423-550; 061-187-993-663-023; 062-110-807-031-390; 064-517-525-551-117; 068-437-948-398-412; 071-520-710-428-381; 080-312-652-272-154; 087-982-249-891-956; 096-576-909-353-399; 109-486-938-033-440; 109-726-720-389-508; 110-009-148-960-446; 119-890-189-378-085; 120-599-935-173-316; 128-576-536-604-472; 132-911-121-330-465; 139-442-852-423-564; 150-856-387-301-913; 172-514-908-210-733; 192-454-073-688-15X; 196-896-974-818-947,1,true,cc-by,hybrid -059-505-525-211-201,Development trends and knowledge framework of artificial intelligence (AI) applications in oncology by years: a bibliometric analysis from 1992 to 2022.,2024-10-16,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Murat Koçak; Zafer Akçalı,"Oncology is the primary field in medicine with a high rate of artificial intelligence (AI) use. Thus, this study aimed to investigate the trends of AI in oncology, evaluating the bibliographic characteristics of articles. We evaluated the related research on the knowledge framework of Artificial Intelligence (AI) applications in Oncology through bibliometrics analysis and explored the research hotspots and current status from 1992 to 2022.; The research employed a scientometric methodology and leveraged scientific visualization tools such as Bibliometrix R Package Software, VOSviewer, and Litmaps for comprehensive data analysis. Scientific AI-related publications in oncology were retrieved from the Web of Science (WoS) and InCites from 1992 to 2022.; A total of 7,815 articles authored by 35,098 authors and published in 1,492 journals were included in the final analysis. The most prolific authors were Esteva A (citaition = 5,821) and Gillies RJ (citaition = 4288). The most active institutions were the Chinese Academy of Science and Harward University. The leading journals were Frontiers ın Oncology and Scientific Reports. The most Frequent Author Keywords are ""machine learning"", ""deep learning,"" ""radiomics"", ""breast cancer"", ""melanoma"" and ""artificial intelligence,"" which are the research hotspots in this field. A total of 10,866 Authors' keywords were investigated. The average number of citations per document is 23. After 2015, the number of publications proliferated.; The investigation of Artificial Intelligence (AI) applications in the field of Oncology is still in its early phases especially for genomics, proteomics, and clinicomics, with extensive studies focused on biology, diagnosis, treatment, and cancer risk assessment. This bibliometric analysis offered valuable perspectives into AI's role in Oncology research, shedding light on emerging research paths. Notably, a significant portion of these publications originated from developed nations. These findings could prove beneficial for both researchers and policymakers seeking to navigate this field.; © 2024. The Author(s).",15,1,566,,Bibliometrics; Internal medicine; Artificial intelligence; Radiomics; Oncology; Computer science; Medicine; Library science,Artificial intelligence; Cancer; Deep learning; Neural network; Oncology,,,Türkiye Bilimsel ve Teknolojik Araştırma Kurumu,,http://dx.doi.org/10.1007/s12672-024-01415-0,39406991,10.1007/s12672-024-01415-0,,PMC11480271,0,000-183-103-477-210; 002-052-422-936-00X; 007-666-838-622-221; 012-013-602-290-876; 013-507-404-965-47X; 014-772-466-372-040; 018-893-501-990-992; 021-131-069-914-209; 025-487-528-665-364; 033-482-601-581-827; 038-439-947-761-188; 039-076-777-343-245; 046-992-864-415-70X; 054-376-898-671-382; 060-606-060-822-405; 061-708-131-411-544; 068-762-846-278-363; 079-617-627-781-370; 079-667-051-092-518; 081-051-040-389-937; 090-970-432-497-682; 092-429-030-442-934; 096-532-070-721-701; 100-445-029-445-191; 105-402-220-957-576; 108-350-274-759-687; 110-147-564-385-036; 113-134-072-098-23X; 120-184-047-744-630; 123-202-581-406-928; 135-917-715-913-736; 146-481-785-480-811; 147-571-560-409-139; 172-818-505-203-080; 198-678-746-883-912; 198-685-598-283-119,2,true,cc-by,gold -059-574-438-300-23X,"Mapping and linking well-being, tourism economics, sustainable tourism and sustainable development: an integrative systematisation of the literature and bibliometric analysis",2025-04-16,2025,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,João Capucho; João Leitão; Helena Alves,"Tourism represents one of the world’s fastest growing and dynamic sectors. It is critical to plan and promote tourism in an intentional and sustainable manner, establishing a balance between a community’s environmental, economic, social and cultural aims. This study provides a systematic literature review and bibliometric analysis to map the key findings and interconnections from research linking sustainable tourism, well-being, sustainable development, and tourism economics. A sample of 223 selected papers is analysed, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, and a bibliometric analysis using the Bibliometrix software is performed. The findings highlight the existence of three significant clusters: (i) sustainable tourism; (ii) tourism; and (iii) well-being; enabling the proposal of a new taxonomy for sustainable tourism, which contributes to the development of a more comprehensive concept of sustainable tourism. These findings contribute to advancing the still limited knowledge on the mapping and linking of emergent topics, such as sustainable tourism, well-being and sustainable development.",6,1,,,Tourism; Sustainable development; Regional science; Sustainable tourism; Geography; Social science; Political science; Sociology; Archaeology; Law,,,,,,http://dx.doi.org/10.1007/s43621-025-01122-y,,10.1007/s43621-025-01122-y,,,0,000-579-954-969-521; 001-814-954-926-568; 002-659-950-558-007; 003-040-282-218-564; 003-042-879-871-16X; 003-976-359-911-198; 004-132-856-568-69X; 005-164-089-732-26X; 006-198-249-323-417; 008-219-626-073-605; 009-784-694-037-735; 009-890-836-458-391; 010-572-728-720-921; 011-264-945-172-29X; 011-617-017-855-259; 013-124-029-603-777; 013-248-302-306-429; 013-507-404-965-47X; 014-374-932-801-639; 015-150-117-155-726; 015-286-269-952-313; 015-403-974-207-941; 016-946-106-019-454; 017-321-520-141-427; 018-444-201-962-590; 019-212-744-669-896; 020-208-746-432-714; 020-411-605-388-098; 022-369-341-687-065; 023-574-653-136-923; 024-321-968-424-728; 024-388-752-379-16X; 024-476-049-407-35X; 024-801-765-987-371; 026-240-827-729-489; 033-634-651-639-564; 034-025-270-462-112; 035-207-705-208-273; 036-979-911-103-612; 042-703-115-580-67X; 044-776-532-451-668; 045-275-765-085-209; 045-286-676-804-834; 046-353-729-407-036; 051-460-593-478-701; 052-484-657-486-376; 052-814-312-373-535; 055-058-901-927-522; 057-172-949-355-772; 059-931-233-378-650; 060-493-469-099-920; 062-739-996-365-944; 064-356-395-819-415; 065-010-405-236-060; 065-302-089-334-121; 066-555-166-310-206; 068-096-966-725-445; 070-778-123-139-130; 071-132-310-517-33X; 071-344-260-002-112; 071-856-935-801-588; 071-890-984-594-318; 072-124-979-926-537; 072-723-465-486-006; 073-771-445-855-081; 073-788-825-065-293; 074-579-145-743-316; 074-707-731-021-678; 075-805-556-259-499; 076-610-869-908-003; 077-023-546-049-435; 077-973-494-528-053; 079-448-233-153-182; 079-699-288-570-182; 080-488-551-600-189; 080-889-189-864-604; 081-008-919-832-801; 083-047-091-086-363; 088-050-392-987-957; 088-414-448-215-329; 090-806-220-925-337; 091-706-675-769-316; 093-064-219-061-104; 093-221-414-080-956; 099-244-695-938-436; 100-016-947-879-41X; 101-064-385-950-415; 102-574-116-934-077; 105-710-172-109-007; 107-276-900-991-821; 109-583-581-147-748; 110-459-063-021-931; 112-200-511-446-475; 114-808-675-503-067; 115-123-645-147-713; 115-207-437-420-058; 116-116-032-953-596; 117-008-121-686-66X; 117-546-854-740-561; 117-748-726-567-173; 118-668-705-407-302; 118-746-437-788-647; 119-339-430-968-678; 119-800-315-664-524; 120-257-915-252-826; 120-418-532-380-120; 123-139-904-793-506; 123-309-280-335-732; 124-752-432-688-557; 129-227-578-883-933; 129-681-622-125-751; 131-234-641-539-754; 131-595-942-326-457; 132-092-951-607-981; 133-254-765-854-351; 133-310-479-880-069; 134-567-777-676-453; 136-542-597-813-141; 138-577-708-444-370; 148-291-710-560-636; 150-100-435-313-178; 153-611-087-329-483; 155-377-162-906-261; 156-118-809-172-271; 157-725-671-370-259; 159-054-921-328-394; 162-024-243-435-772; 168-822-796-656-30X; 169-386-296-318-687; 169-643-034-600-900; 170-472-684-447-946; 172-350-873-397-367; 173-073-365-163-584; 173-982-317-265-330; 174-665-202-037-490; 190-755-865-313-467; 191-699-991-248-240; 192-595-241-804-228; 197-791-980-607-017,1,true,cc-by,gold -059-614-901-115-786,Using qualitative comparative analysis approach in tourism studies: a critical review,2023-05-08,2023,journal article,Quality & Quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Onur Selcuk; Beykan Cizel,,58,1,933,960,Qualitative comparative analysis; Tourism; Rubric; Computer science; Quality (philosophy); Set (abstract data type); Management science; Process (computing); Marketing; Data science; Psychology; Business; Economics; Political science; Epistemology; Machine learning; Philosophy; Mathematics education; Law; Programming language; Operating system,,,,,,http://dx.doi.org/10.1007/s11135-023-01675-y,,10.1007/s11135-023-01675-y,,,0,000-929-286-060-562; 004-263-839-839-152; 004-582-588-826-610; 004-612-842-069-518; 005-081-856-613-154; 005-091-700-178-597; 007-405-774-385-080; 008-949-608-901-627; 008-964-851-716-62X; 009-358-541-076-395; 013-117-250-891-864; 013-427-352-824-551; 013-507-404-965-47X; 013-738-836-217-326; 015-427-115-111-884; 015-714-071-729-86X; 015-789-793-675-740; 017-956-614-947-500; 018-639-359-132-642; 021-022-932-914-507; 021-782-362-290-369; 022-653-614-913-100; 023-722-384-816-163; 023-838-134-291-821; 026-129-620-336-105; 026-276-649-339-772; 028-790-026-932-603; 028-872-076-298-734; 031-004-583-107-769; 031-531-249-388-213; 031-597-598-211-717; 032-068-535-387-793; 033-529-627-487-586; 035-061-927-263-746; 035-143-825-628-352; 036-173-533-432-669; 036-371-727-382-804; 037-920-703-446-178; 038-297-147-021-834; 038-499-879-416-220; 039-480-660-082-349; 040-328-364-385-838; 040-541-065-879-208; 041-260-249-898-02X; 041-315-883-436-581; 045-647-725-242-972; 046-755-074-575-443; 046-761-035-722-405; 046-815-358-274-37X; 047-126-197-113-542; 047-194-128-425-248; 047-805-222-462-571; 048-080-722-942-679; 049-126-267-323-688; 052-000-381-850-865; 052-139-277-983-111; 052-439-448-676-840; 052-624-353-926-709; 053-022-081-093-763; 053-938-108-007-977; 055-279-302-638-517; 058-265-899-612-265; 058-565-235-835-962; 059-172-033-793-564; 059-244-137-820-061; 062-431-001-839-523; 064-076-750-122-641; 064-554-008-630-186; 066-743-645-416-727; 068-458-598-960-542; 068-764-254-821-309; 069-231-267-197-482; 069-332-459-737-802; 071-277-449-313-734; 071-289-035-172-917; 073-397-825-893-437; 073-812-352-911-935; 075-557-430-341-040; 077-100-579-881-777; 080-851-715-295-20X; 081-795-135-446-481; 082-706-235-854-633; 083-233-429-885-517; 083-440-358-186-912; 084-469-422-495-994; 086-048-314-388-101; 088-397-522-969-697; 091-469-987-116-14X; 091-576-660-395-785; 091-719-074-891-722; 092-774-914-111-839; 094-694-140-901-708; 095-053-444-689-589; 096-656-102-144-393; 097-488-122-121-961; 100-268-029-418-500; 101-523-794-160-270; 103-557-844-227-639; 105-996-056-076-531; 106-161-222-101-503; 107-471-404-886-33X; 107-645-184-835-908; 109-208-772-540-37X; 109-686-386-922-173; 109-724-474-878-242; 109-741-161-144-066; 110-895-103-417-692; 117-540-209-815-252; 118-803-644-845-155; 119-742-325-798-531; 123-040-336-510-01X; 123-507-533-333-741; 126-539-010-069-799; 129-646-895-610-265; 131-162-647-829-453; 132-500-680-675-148; 136-090-675-118-204; 136-182-182-706-399; 136-274-763-006-479; 138-257-828-299-646; 139-156-220-277-581; 140-082-406-363-724; 142-022-577-794-084; 144-973-417-843-752; 145-922-896-905-549; 146-414-249-525-078; 149-649-938-878-085; 149-775-342-010-098; 151-103-161-057-735; 151-748-674-873-701; 152-597-615-140-488; 153-661-844-093-89X; 154-346-740-118-884; 155-439-359-230-171; 156-407-940-179-509; 163-910-278-524-145; 172-489-959-150-812; 175-299-190-621-487; 180-230-815-936-231; 185-494-842-730-117; 185-697-991-918-818; 186-509-939-570-178; 187-074-670-444-991; 191-065-011-986-420; 191-198-103-619-811; 192-879-087-284-774,5,false,, -060-071-848-779-221,Biblioshiny R Aplication on Islamic Sosial Finance,2024-03-30,2024,journal article,Cakrawala Repositori IMWI,26208814; 26208490,Institut Manajemen Wiyata Indonesia,,Muh Aswad; Ries Wulandari,"Penelitian ini bertujuan untuk mengetahui perkembangan tren penelitian keuaangan sosial islam yang diterbitkan oleh jurnal-jurnal terkemuka di bidanng ekonomi keuangan Islam. Data yang dianalisis dari 59 publikasi penelitian di scopus. Kata kunci pencariannya adalah “ISF Zakat Waqf Muslim”. Pencarian digunakan untuk menetapkan dataset studi terakhir diperbaharui pada Agustus 2023. Metode statistic deskriptif digunakan, dan analisis bibliometrix dilakukan menggunakan biblioshiny, aplikasi berbasis R, untuk menghasilkan peta bibliometrix. Jumlah artikel yang membahas Islamic Sosial finance cukup banyak dalam beberapa bulan terakhir, dengan lebih dari 50 artikel yang diterbitkan. Kata kunci yang paling populer yang digunakan dengan topik Isalmic Sosial Finance (zakat dan Waqf ) adalah “Islamic”, kata yang paling umum kedua adalah “Waqf”, kata yang paling umum ketiga “Zakat”. Adapun kata kunci yang terkait adalah “Indonesia”, ""Malaysia” kemudian selanjutnya “philanthropy"", ""accounting, poverty, development, perspective, social, syariah"". Penelitian ini memberikan gambaran tentang tren kata kunci, jurnal, dan penulis artikel paling populer dengan topik Islamic Sosial Finance (Zakat dan Waqf), yang menjadi tema yang cukup populer dalam beberapa tahun terakhir, sehinggal memberikan informasi bagi para peneliti yang konsen dalam bidang tersebut.",7,2,3526,3537,Islam; Islamic finance; Economics; Business; Philosophy; Theology,,,,,https://cakrawala.imwi.ac.id/index.php/cakrawala/article/download/664/609 https://doi.org/10.52851/cakrawala.v7i02.664,http://dx.doi.org/10.52851/cakrawala.v7i02.664,,10.52851/cakrawala.v7i02.664,,,0,,0,true,cc-by-sa,hybrid -060-424-680-403-095,"Spanning 36 years, the evolution and trend of word-of-mouth marketing research – based on bibliometrix analysis",,2022,journal article,Academic Journal of Business & Management,26165902,Francis Academic Press Ltd.,,Zhen-Cheng Huang; Zhe Chen,"Word of mouth is an important influencing factor of customers' purchase decision-making behavior, and also a key basis for product promotion and improvement in business activities. Word of mouth marketing is a new tool of marketing, which has a special communication mechanism and characteristics, and is the main focus of business activity research. Based on the retrieval data of web of science, this study uses bibliometrix software to conduct network econometric analysis on 259 literatures on word-of-mouth marketing in the past 36 years. The research on word-of-mouth marketing is divided into three stages, focusing on the evolution of research topics and future development trends.",4,8,,,Word of mouth; Promotion (chess); Marketing research; Marketing; Product (mathematics); Computer science; Advertising; Business; Political science; Geometry; Mathematics; Politics; Law,,,,,https://francis-press.com/uploads/papers/TFNaUkn9k84mmNwSDwf4KUESxl4QVZgYKo7zDcmN.pdf https://doi.org/10.25236/ajbm.2022.040819,http://dx.doi.org/10.25236/ajbm.2022.040819,,10.25236/ajbm.2022.040819,,,0,,1,true,,bronze -060-585-977-243-632,A Bibliometric Analysis of Digital Health & Mobile Health Related Global Research Publications.,2022-04-05,2022,journal article,Hospital topics,19399278; 00185868,Informa UK Limited,United States,Jayesh Aagja; Samik Shome; Ashish Chandra,"The dataset was generated from Scopus database for the study due to its compatibility with bibliometrix R package. The dataset shows that there is a gradual increase in publication of research articles on digital health and mobile health till 2016 before a sudden rise in number of publications from 2017 onwards. This paper contributes by providing a consolidation of fragmented literature in the research domain giving us information on significant sources, authors and documents. The analysis of conceptual structure reveals that the topics of study have evolved from mobile health to digital health, e-health, technology acceptance model, privacy, implementation and self-management.",101,4,319,325,Scopus; Digital health; Data science; Consolidation (business); Computer science; Health information; World Wide Web; Knowledge management; MEDLINE; Political science; Health care; Business; Accounting; Law,Digital health; bibliometric analysis; bibliometrix R; m-health; mobile health,Humans; Bibliometrics; Privacy; Telemedicine,,Indian Council of Social Science Research,,http://dx.doi.org/10.1080/00185868.2022.2060155,35380102,10.1080/00185868.2022.2060155,,,0,018-752-143-906-690; 019-427-467-229-232; 023-641-077-545-477; 042-428-706-598-501; 044-306-570-813-096; 061-640-050-996-212; 071-878-836-294-733; 089-704-578-826-744; 097-497-635-514-204; 101-752-490-869-458,12,false,, -060-657-054-872-537,Conceptual Modeling Education,2025-02-15,2025,journal article,Business & Information Systems Engineering,23637005; 18670202; 09376429,Springer Science and Business Media LLC,Germany,Ilia Maslov; Stephan Poelmans; Kristina Rosenthal,,,,,,Computer science; Conceptual model; Knowledge management; Database,,,,,,http://dx.doi.org/10.1007/s12599-025-00930-w,,10.1007/s12599-025-00930-w,,,0,007-724-168-340-411; 008-088-338-153-136; 010-322-480-073-393; 013-507-404-965-47X; 013-524-854-219-241; 014-230-308-388-69X; 017-750-600-412-958; 020-243-881-576-132; 021-651-427-047-942; 023-927-221-065-800; 025-441-977-869-369; 027-793-681-875-534; 030-319-171-764-105; 030-351-847-885-848; 032-029-721-543-575; 032-831-522-836-007; 033-445-999-257-281; 033-910-490-263-25X; 035-924-630-843-994; 038-178-962-530-852; 038-363-207-084-945; 043-328-410-802-946; 043-515-938-005-447; 046-725-449-959-340; 046-992-864-415-70X; 049-995-260-408-245; 053-541-234-117-872; 054-501-011-008-089; 056-690-811-230-444; 064-745-794-525-229; 064-916-077-008-118; 068-464-257-781-766; 069-055-488-527-836; 069-532-647-509-985; 070-139-550-235-134; 077-556-534-968-022; 088-241-683-217-786; 093-504-913-126-218; 094-889-077-381-18X; 108-430-265-533-221; 109-707-112-050-515; 131-816-728-119-605; 133-250-061-081-129; 151-002-460-600-782; 152-528-094-149-655; 153-143-055-208-148; 156-494-755-078-421; 178-590-731-392-772; 199-902-735-686-251,0,false,, -060-708-634-880-434,Türkiye'de Görev Yapan Muhasebe Akademisyenlerinin Uluslararası Görünürlüğü Üzerine Bir Araştırma,2024-04-04,2024,journal article,Muhasebe ve Finansman Dergisi,21463042,Muhasebe ve Finansman Dergisi,,Bilge Katanalp,"Bu çalışmanın amacı Türkiye’de görev yapan muhasebe akademisyenlerinin uluslararası veri tabanlarında bulunan bilimsel çalışmalarının durumunu ortaya çıkarmaktır. Bibliyometrik analiz ve görselleştirme için VOSviewer ve RStudio Bibliometrix programları kullanılmıştır. Analize dahil edilen 382 çalışma Web of Science Core Collection veri tabanından elde edilmiştir. Sonuç olarak tek bir yazar veya kurumun çok fazla öne çıkmadığı gözlemlenmiştir. Ayrıca araştırma alanlarından muhasebe eğitimi ve meslek mensuplarına yönelik çalışmalar sürekli olarak güncel kalırken, son zamanlarda muhasebe tarihi alanındaki çalışmalar öne çıkmıştır. Son olarak performans analizi ve etkililik üzerine yapılan çalışmaların artış göstermesiyle ampirik çalışmaların daha popüler hale geldiği anlaşılmaktadır. Bu çalışma VOSviewer ve Bibliometrix i aynı anda kullanarak muhasebe alanında yapılan bibliyometrik çalışmalardan yöntem bakımından ayrışmaktadır. Ayrıca daha önce Türkiye’de görev yapan muhasebe akademisyenlerinin uluslararası görünürlüğünü araştıran bir çalışma bulunmamaktadır.",0,102,39,56,Humanities; Political science; Art; Physics,,,,,https://dergipark.org.tr/tr/download/article-file/3623991 https://dergipark.org.tr/tr/pub/mufad/issue/84061/1410738,http://dx.doi.org/10.25095/mufad.1410738,,10.25095/mufad.1410738,,,0,000-667-231-896-402; 002-052-422-936-00X; 009-827-584-458-472; 013-271-533-609-908; 013-507-404-965-47X; 014-598-493-482-64X; 015-358-040-028-034; 015-783-413-622-392; 027-123-536-258-975; 028-174-873-054-822; 028-727-407-337-232; 032-095-525-795-674; 036-415-814-901-678; 038-468-560-005-647; 046-992-864-415-70X; 051-083-383-367-500; 054-452-304-347-975; 060-829-554-921-575; 073-488-491-193-134; 091-462-108-649-440; 091-945-840-524-91X; 096-024-320-573-30X; 102-217-511-641-113; 103-214-949-434-277; 105-284-963-065-187; 107-018-489-248-074; 107-619-073-032-142; 111-714-779-581-100; 117-114-158-069-656; 146-906-769-416-60X; 160-463-524-471-472; 161-710-107-332-537; 171-274-748-694-989; 171-593-955-571-082; 193-995-104-011-642; 195-543-495-086-830; 199-577-936-044-590,2,true,,gold -060-775-395-093-440,Artificial Intelligence and Data Science Methods for Automatic Detection of White Blood Cells in Images.,2025-05-16,2025,journal article,Journal of imaging informatics in medicine,29482933; 29482925,Springer Science and Business Media LLC,Switzerland,Yawo M Kobara; Ikpe Justice Akpan; Alima Damipe Nam; Firas H AlMukthar; Mbuotidem Peter,"Data scieQuerynce (DS) methods and artificial intelligence (AI) are critical in today's healthcare services operations. This study focuses on evaluating the effectiveness of AI and DS in biomedical diagnostics, including automatic detection and counting of white blood cells (WBCs) and types, which provide valuable information for diagnosing and treating blood diseases such as leukemia. Automating these tasks using AI and DS saves time and avoids or minimizes errors compared to manual processes, which can be complex and error prone. The study utilizes bibliographic data from SCOPUS to evaluate research on applying AI algorithms and DS methods for mapping and classifying WBC images for treatment of blood diseases, such as leukemia using literature survey and science mapping methodology. The results show the potency of different DS methods and AI algorithms, such as machine learning, deep learning, and classification algorithms that enable the automatic detection of WBC images. AI and DS algorithms offer critical benefits in effectively and efficiently analyzing microscopic images of blood cells. The automatic identification, localization, and classification of WBCs speed up the patient diagnosis process, allowing hematologists to focus on interpreting results. Automatic processes identify specific abnormalities and patterns, enhancing accuracy and timely diagnoses. Future work will examine the application of generative AI in blood cells diagnostics.",,,,,,Artificial intelligence; Blood cells images segmentation; Blood disease; Data science methods; Deep learning; Diagnosing blood diseases processes; Generative artificial intelligence; Leukemia; Machine learning; White blood cells detection,,,,,http://dx.doi.org/10.1007/s10278-025-01538-y,40379861,10.1007/s10278-025-01538-y,,,0,001-379-757-683-882; 002-052-422-936-00X; 002-366-973-756-752; 004-136-801-703-143; 005-972-101-309-25X; 006-203-772-316-936; 007-395-524-306-558; 007-958-134-693-448; 009-574-850-024-800; 010-899-638-574-400; 011-871-848-229-551; 013-507-404-965-47X; 013-801-369-957-796; 014-500-819-642-095; 016-571-548-585-455; 018-564-057-972-562; 019-591-481-712-145; 019-791-216-160-921; 020-782-944-285-272; 021-391-310-519-426; 022-467-524-287-995; 024-376-723-317-56X; 026-292-208-778-657; 026-396-800-357-188; 026-514-239-702-656; 026-601-923-898-54X; 027-186-120-480-669; 027-950-346-486-941; 029-205-345-798-268; 030-065-697-283-069; 031-534-334-474-97X; 033-263-762-093-197; 035-688-623-932-911; 036-493-229-256-026; 037-616-743-437-325; 037-943-743-306-737; 038-511-823-405-644; 039-477-178-699-896; 040-995-433-165-417; 041-282-954-755-726; 042-107-537-134-134; 044-054-681-631-350; 044-352-879-164-394; 044-699-737-827-175; 045-915-523-880-659; 046-475-567-507-477; 046-992-864-415-70X; 050-636-859-637-627; 051-906-121-258-413; 052-558-589-227-186; 054-772-236-060-536; 055-361-644-655-483; 057-713-675-920-912; 063-165-655-710-718; 064-179-900-307-214; 064-481-218-236-035; 065-010-405-236-060; 073-426-945-310-611; 074-099-012-262-452; 076-796-807-716-581; 079-806-169-864-891; 081-125-677-349-923; 089-030-444-116-976; 090-313-119-943-746; 092-492-061-311-779; 095-141-943-178-425; 097-626-982-129-739; 098-917-490-181-852; 104-452-570-331-054; 105-410-582-303-748; 106-568-283-794-731; 110-800-867-001-342; 115-871-634-244-650; 115-927-208-468-782; 118-017-660-083-260; 122-647-073-832-555; 122-896-647-564-383; 125-459-275-946-295; 137-723-156-179-076; 146-555-724-313-170; 150-215-517-638-582; 151-279-496-517-501; 151-839-383-675-637; 151-858-282-909-784; 152-273-245-091-023; 160-315-462-914-05X; 162-633-553-600-730; 166-026-308-850-139; 176-457-688-629-037; 180-575-805-999-099; 191-191-840-907-037; 194-514-844-415-665; 194-672-817-010-674,0,true,cc-by,hybrid -061-103-086-734-691,Ten years of researches on generalized anxiety disorder (GAD): a scientometric review,2024-04-11,2024,journal article,Current Psychology,10461310; 19364733,Springer Science and Business Media LLC,United States,Ying Zhou; Yulin Luo; Na Zhang; Shen Liu,,43,24,21393,21408,Psychology; Generalized anxiety disorder; Anxiety; Clinical psychology; Psychiatry,,,,Outstanding Youth Program of Philosophy and Social Sciences in Anhui Province; Starting Fund for Scientific Research of High-Level Talents at Anhui Agricultural University,,http://dx.doi.org/10.1007/s12144-024-05872-2,,10.1007/s12144-024-05872-2,,,0,001-783-525-966-722; 002-381-301-173-12X; 004-346-873-594-13X; 006-983-129-233-082; 008-216-756-299-238; 008-515-740-586-697; 008-573-139-685-083; 012-080-130-771-080; 012-515-777-825-81X; 013-455-415-639-790; 014-849-011-943-460; 015-612-897-385-541; 017-839-472-387-92X; 019-605-394-332-245; 026-926-971-999-498; 027-115-329-780-47X; 028-335-216-907-164; 030-878-412-558-355; 034-924-263-035-787; 035-745-192-345-587; 038-958-501-071-435; 039-708-732-515-683; 040-159-833-110-104; 044-717-016-042-489; 045-334-595-619-657; 045-599-848-835-176; 046-329-946-284-327; 048-173-089-944-953; 053-867-581-981-454; 054-077-940-753-649; 054-361-560-512-710; 055-229-443-956-505; 056-028-135-907-803; 057-406-554-123-01X; 062-461-302-482-369; 064-400-499-357-900; 065-065-880-861-55X; 068-258-000-927-515; 068-481-985-610-994; 075-590-459-490-570; 079-794-421-938-464; 085-289-550-717-254; 086-037-257-522-226; 087-062-117-434-380; 090-731-522-534-055; 095-540-282-210-851; 096-065-434-418-421; 099-259-824-393-711; 099-646-231-902-576; 111-854-693-833-682; 115-892-208-618-595; 121-115-506-401-491; 125-107-178-744-297; 130-456-716-771-724; 131-423-542-523-282; 135-001-838-836-363; 155-134-308-450-724; 158-808-859-416-685; 185-321-538-982-429,2,false,, -061-131-759-048-636,Gender representation in textbooks: a bibliometric study,2023-09-16,2023,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Yijie Dong; Danyang Li,,128,11,5969,6001,Field (mathematics); Representation (politics); Theme (computing); Multidisciplinary approach; Bibliometrics; Sociology; Computer science; Data science; Social science; Library science; Political science; World Wide Web; Politics; Mathematics; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1007/s11192-023-04834-y,,10.1007/s11192-023-04834-y,,,0,000-300-498-652-756; 000-850-445-261-838; 000-909-591-187-553; 001-679-351-708-909; 001-719-026-803-199; 002-081-198-992-578; 004-165-806-695-894; 004-819-527-814-707; 005-691-972-823-245; 007-833-703-147-705; 009-450-061-158-975; 011-077-316-451-954; 013-507-404-965-47X; 014-766-751-437-017; 014-870-258-354-234; 015-774-079-830-633; 016-802-516-408-652; 017-750-600-412-958; 018-662-297-942-863; 019-290-367-674-721; 020-847-216-114-437; 025-222-795-806-893; 026-472-996-417-083; 027-087-301-035-050; 028-327-331-979-091; 029-990-816-739-915; 031-091-329-408-927; 039-155-986-997-996; 039-415-065-353-406; 042-049-902-956-994; 042-328-787-516-249; 043-551-381-671-458; 044-023-451-726-379; 044-603-291-972-175; 045-103-914-453-669; 046-992-864-415-70X; 047-134-478-431-993; 048-478-934-614-984; 049-010-896-534-213; 049-619-871-030-254; 049-930-635-144-112; 050-320-351-581-22X; 051-515-640-422-184; 052-279-558-744-082; 055-641-480-735-351; 056-421-980-817-283; 057-738-735-414-343; 057-803-697-074-453; 062-723-932-400-521; 064-589-935-699-918; 067-698-916-760-084; 069-122-959-954-840; 077-875-053-306-27X; 078-933-614-597-53X; 080-301-541-339-949; 080-735-211-188-285; 082-746-240-950-490; 084-439-904-287-226; 087-608-832-966-839; 088-342-840-782-440; 092-190-082-287-575; 094-596-515-422-123; 096-786-974-963-818; 097-186-178-807-360; 102-978-135-278-90X; 108-990-231-366-731; 111-634-690-012-411; 118-445-475-164-625; 119-057-323-803-506; 120-920-544-940-379; 120-974-286-046-262; 121-652-742-486-910; 127-930-727-923-452; 130-256-867-233-054; 131-882-213-909-355; 137-850-187-048-089; 155-314-032-909-87X; 167-887-017-932-16X; 170-671-035-519-702; 188-278-424-875-914,5,false,, -061-155-386-855-545,Evolution of customer relationship management to data mining-based customer relationship management: a scientometric analysis.,2022-08-27,2022,journal article,Quality & quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Minnu F Pynadath; T M Rofin; Sam Thomas,"Scores of researchers have paid attention to empirical and conceptual dimensions of Customer relationship management (CRM). A few studies summarise the research output of CRM focusing on a specific industry. Nevertheless, there is scant literature summarising the research output of CRM in contrast to the data mining-based CRM. This study presents a scientometric analysis that evaluates CRM research output with a special focus on data mining-based CRM. Bibliometric data were extracted for the period 2000-2020 from the Web of Science database to apply descriptive analysis and scientometric analysis to obtain the bibliometric profile of CRM research. Further, we generated the conceptual structure map using multiple correspondence analysis and clustering for CRM and data mining-based CRM research fields. Interestingly, the analysis revealed that the future trendfi of CRM research would be based on techniques associated with machine learning and artificial intelligence. The study provides extensive insight into the basic structure of the CRM and data mining-based CRM research domain and identifies future research areas.",57,4,1,3272,Customer relationship management; Data science; Computer science; Data mining; Knowledge management; Cluster analysis; Artificial intelligence; Database,CRM; Citation analysis; Conceptual structure map; Data mining; Scientometric analysis,,,,https://link.springer.com/content/pdf/10.1007/s11135-022-01500-y.pdf https://doi.org/10.1007/s11135-022-01500-y,http://dx.doi.org/10.1007/s11135-022-01500-y,36060545,10.1007/s11135-022-01500-y,,PMC9418653,0,001-719-026-803-199; 003-485-902-438-19X; 004-306-474-288-542; 005-099-032-563-567; 005-358-712-520-601; 007-038-554-766-146; 007-804-265-100-065; 009-545-864-226-187; 012-727-794-775-839; 012-949-568-153-277; 013-507-404-965-47X; 016-576-335-079-156; 019-363-859-170-946; 019-950-379-239-023; 020-674-863-879-249; 021-297-044-640-344; 025-878-197-376-805; 029-329-456-541-152; 031-082-232-350-816; 034-607-978-519-591; 034-658-158-500-326; 039-148-653-533-012; 039-610-238-884-525; 046-718-391-639-372; 055-166-630-285-078; 058-734-447-624-600; 060-034-722-334-881; 060-143-780-575-926; 062-338-868-701-109; 063-553-561-593-850; 068-197-981-329-136; 068-408-551-842-842; 071-747-220-846-720; 072-350-575-479-916; 074-171-468-110-493; 077-246-216-426-515; 078-793-084-989-859; 085-667-772-498-603; 088-347-934-082-755; 090-246-132-180-600; 091-453-940-572-723; 098-659-612-113-067; 101-218-071-021-68X; 102-157-583-193-530; 104-040-369-903-806; 107-452-141-732-721; 112-448-916-399-303; 116-260-916-410-77X; 116-545-996-099-174; 120-031-301-873-562; 120-974-286-046-262; 122-431-604-826-507; 132-915-097-654-715; 134-338-670-344-29X; 136-885-927-214-876; 137-690-740-505-450; 138-684-993-786-479; 141-200-607-894-303; 144-326-877-678-38X; 145-857-677-722-197; 152-354-399-696-177; 154-200-701-126-708; 177-371-545-436-595,10,true,,bronze -061-258-184-899-138,The status of and trends in the pharmacology of berberine: a bibliometric review [1985-2018].,2020-01-20,2020,journal article,Chinese medicine,17498546,Springer Science and Business Media LLC,United Kingdom,Yu Gao; Feng-xue Wang; Yanjun Song; Haibo Liu,"Berberine has significant antibacterial and antipyretic effects and is a commonly used drug for treating infectious diarrhoea. The current research data show that the pharmacological effects of berberine are numerous and complex, and researchers have been enthusiastic about this field. To allow researchers to quickly understand the field and to provide references for the direction of research, using bibliometrics, we analysed 1426 articles, dating from 1985 to 2018, in the field of berberine pharmacology. The research articles we found came from 69 countries/regions, 1381 institutions, 5675 authors, and 325 journals; they contained 3794 key words; they were written in 7 languages; and they were of 2 article types. This study summarizes and discusses the evolution of the historical themes of berberine pharmacology as well as the status quo and the future development directions from a holistic perspective.",15,1,7,7,Psychology; Bibliometrics; Status quo; Berberine; Infectious diarrhoea; Research data; Web of science; Pharmacology,Berberine; Bibliometrics; CiteSpace; Evolutionary trend; Pharmacology; Web of Science,,,the National Mega-Project for Innovative Drugs; the Science and Technology Innovation Project of the Chinese Academy of Medical Sciences,https://cmjournal.biomedcentral.com/articles/10.1186/s13020-020-0288-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971869 https://pubmed.ncbi.nlm.nih.gov/31988653/ https://link.springer.com/content/pdf/10.1186/s13020-020-0288-z.pdf https://europepmc.org/article/MED/31988653 https://link.springer.com/article/10.1186/s13020-020-0288-z,http://dx.doi.org/10.1186/s13020-020-0288-z,31988653,10.1186/s13020-020-0288-z,3006910012,PMC6971869,0,000-328-642-389-417; 001-393-001-635-312; 001-738-334-497-334; 003-868-747-830-164; 005-039-946-576-765; 006-461-237-333-939; 006-592-468-699-321; 006-996-392-188-197; 008-294-104-769-55X; 009-721-804-001-760; 010-764-994-503-600; 011-670-004-749-388; 011-928-609-434-675; 011-957-369-731-656; 012-253-149-992-257; 012-285-911-105-215; 013-507-404-965-47X; 015-965-540-244-942; 017-604-560-028-824; 018-621-425-019-109; 018-707-099-272-279; 018-887-607-977-111; 019-137-450-883-46X; 019-140-819-714-613; 021-353-347-663-520; 024-638-911-479-993; 024-693-535-696-581; 025-575-968-786-944; 026-395-112-558-483; 026-891-372-421-849; 028-550-418-435-072; 029-496-545-296-425; 032-231-821-228-790; 032-445-681-667-460; 033-791-707-521-813; 036-216-370-918-193; 036-383-120-863-271; 036-656-168-693-890; 036-778-901-874-172; 040-959-990-181-825; 044-267-557-169-84X; 044-634-527-409-752; 045-758-128-564-692; 049-594-844-008-248; 050-814-273-084-673; 050-920-548-458-072; 051-695-980-582-900; 052-319-958-759-738; 054-112-380-653-391; 055-827-578-094-754; 055-967-381-485-078; 056-735-227-987-612; 057-306-204-182-599; 059-686-780-193-034; 060-155-143-391-284; 061-877-295-914-153; 061-884-763-212-968; 063-005-758-691-852; 063-694-464-901-638; 064-332-825-417-592; 066-249-625-781-803; 066-933-520-813-814; 068-233-017-918-470; 074-892-417-802-326; 075-434-111-549-346; 079-597-769-368-72X; 084-608-456-631-664; 087-031-363-823-179; 090-731-522-534-055; 097-760-078-825-59X; 099-898-258-021-227; 101-201-232-713-249; 101-752-490-869-458; 107-768-574-755-487; 108-869-685-430-430; 120-237-320-828-373; 138-561-175-358-392; 153-601-968-845-446,47,true,"CC BY, CC0",gold -061-449-323-187-491,Bibliometric Analysis of Computational and Mathematical Models of Innovation and Technology in Business,2023-06-26,2023,journal article,Axioms,20751680,MDPI AG,,Mauricio Castillo-Vergara; Víctor Muñoz-Cisterna; Cristian Geldes; Alejandro Álvarez-Marín; Mónica Soto-Marquez,"There is consensus, both in academia and in the business world, that one of the main resources of a company is the incorporation of technology and, along with this, its capacity to generate innovation. Therefore, knowing the development of a company’s research becomes essential. The aim of this work is to develop a bibliometric analysis of the literature published in the Web of Science database to analyze the advances and trends in the development of research. The methodology analyzed bibliometric quantity and quality indicators using Bibliometrix, VOSviewer, and SciMAT software. The results show the evolution of the topic as well as recognition of the different lines along which research has organized the debate.",12,7,631,631,Bibliometrics; Work (physics); Computer science; Data science; Knowledge management; Quality (philosophy); Management science; Engineering; World Wide Web; Mechanical engineering; Philosophy; Epistemology,,,,Agencia Nacional de Investigación y Desarrollo of Chile (ANID),https://www.mdpi.com/2075-1680/12/7/631/pdf?version=1687763339 https://doi.org/10.3390/axioms12070631,http://dx.doi.org/10.3390/axioms12070631,,10.3390/axioms12070631,,,0,000-101-293-112-404; 000-307-904-142-455; 001-009-385-406-527; 002-468-528-927-960; 002-864-044-698-203; 002-888-034-597-27X; 008-411-766-052-718; 009-043-653-181-556; 009-103-742-223-721; 011-804-302-907-058; 012-430-490-977-768; 013-711-240-310-896; 014-044-412-469-482; 014-552-030-082-013; 014-582-724-132-334; 016-734-565-263-128; 017-184-439-013-50X; 017-394-279-330-244; 018-464-652-178-488; 018-921-990-361-454; 020-431-537-281-480; 023-036-388-175-594; 023-465-204-273-153; 023-592-781-477-318; 023-885-530-915-677; 023-901-293-482-245; 025-402-274-938-418; 027-972-359-096-173; 028-360-409-617-061; 029-711-296-755-73X; 029-931-955-901-556; 031-701-151-113-499; 034-246-887-314-741; 034-804-981-435-607; 036-509-257-765-964; 040-370-425-078-321; 045-558-093-025-528; 046-831-690-366-575; 046-992-864-415-70X; 048-589-873-226-911; 050-516-400-336-138; 050-575-307-856-77X; 051-647-739-244-271; 053-760-941-442-404; 054-543-152-104-272; 054-618-977-714-175; 058-081-424-637-980; 058-411-452-007-766; 060-110-039-971-60X; 061-711-587-552-115; 063-757-530-177-971; 064-112-115-116-272; 065-829-318-927-563; 065-963-098-619-864; 066-709-734-456-721; 066-849-661-222-258; 072-856-861-900-730; 076-416-008-465-774; 078-068-053-103-507; 083-233-429-885-517; 085-300-287-100-525; 086-774-868-147-736; 092-353-895-976-662; 095-583-168-218-577; 100-346-811-070-250; 100-445-029-445-191; 102-097-738-342-51X; 105-606-187-469-603; 106-455-930-498-621; 122-607-354-956-646; 124-814-014-669-995; 132-061-854-363-821; 134-022-329-133-922; 138-944-729-770-978; 142-692-498-330-567; 144-582-985-420-207; 145-472-068-060-194; 146-211-606-996-063; 157-023-225-339-271; 158-083-998-554-898; 164-311-599-310-06X; 168-036-345-097-619; 175-115-479-699-85X; 187-561-743-720-474; 191-165-450-777-127; 195-638-802-395-994,7,true,cc-by,gold -061-538-402-818-954,Scientific production and thematic breakthroughs in smart learning environments: a bibliometric analysis,2021-01-15,2021,journal article,Smart learning environments,21967091,Springer Science and Business Media LLC,Germany,Friday Joseph Agbo; Solomon Sunday Oyelere; Jarkko Suhonen; Markku Tukiainen,"This study examines the research landscape of smart learning environments by conducting a comprehensive bibliometric analysis of the field over the years. The study focused on the research trends, scholar’s productivity, and thematic focus of scientific publications in the field of smart learning environments. A total of 1081 data consisting of peer-reviewed articles were retrieved from the Scopus database. A bibliometric approach was applied to analyse the data for a comprehensive overview of the trend, thematic focus, and scientific production in the field of smart learning environments. The result from this bibliometric analysis indicates that the first paper on smart learning environments was published in 2002; implying the beginning of the field. Among other sources, “Computers & Education,” “Smart Learning Environments,” and “Computers in Human Behaviour” are the most relevant outlets publishing articles associated with smart learning environments. The work of Kinshuk et al., published in 2016, stands out as the most cited work among the analysed documents. The United States has the highest number of scientific productions and remained the most relevant country in the smart learning environment field. Besides, the results also showed names of prolific scholars and most relevant institutions in the field. Keywords such as “learning analytics,” “adaptive learning,” “personalized learning,” “blockchain,” and “deep learning” remain the trending keywords. Furthermore, thematic analysis shows that “digital storytelling” and its associated components such as “virtual reality,” “critical thinking,” and “serious games” are the emerging themes of the smart learning environments but need to be further developed to establish more ties with “smart learning”. The study provides useful contribution to the field by clearly presenting a comprehensive overview and research hotspots, thematic focus, and future direction of the field. These findings can guide scholars, especially the young ones in field of smart learning environments in defining their research focus and what aspect of smart leaning can be explored.",8,1,1,25,Deep learning; Adaptive learning; Personalized learning; Artificial intelligence; Data science; Learning analytics; Digital storytelling; Field (computer science); Computer science; Critical thinking; Thematic analysis,Bibliometric analysis; Bibliometrix R-package; Biblioshiny; Research trends; Science mapping; Smart learning environments,,,,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810194/ https://link.springer.com/content/pdf/10.1186/s40561-020-00145-4.pdf http://www.diva-portal.se/smash/record.jsf?pid=diva2%3A1518672&c=14887&searchType=SIMPLE&language=sv&af=%5B%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all https://slejournal.springeropen.com/articles/10.1186/s40561-020-00145-4 https://link.springer.com/article/10.1186/s40561-020-00145-4 https://link.springer.com/article/10.1186/s40561-020-00145-4/figures/11 https://dblp.uni-trier.de/db/journals/sle/sle8.html#AgboOST21 https://erepo.uef.fi/handle/123456789/24751 http://www.diva-portal.org/smash/record.jsf?pid=diva2:1518672,http://dx.doi.org/10.1186/s40561-020-00145-4,40477293,10.1186/s40561-020-00145-4,3127908559,PMC7810194,0,001-880-784-531-357; 004-127-932-786-175; 007-016-826-558-870; 011-800-349-240-213; 013-507-404-965-47X; 015-212-893-203-031; 017-011-508-859-491; 017-703-379-345-992; 017-750-600-412-958; 019-251-005-587-717; 022-133-380-528-023; 024-054-403-376-534; 027-658-377-324-664; 028-765-557-369-43X; 029-833-849-343-221; 031-850-650-589-351; 035-030-071-081-969; 035-926-197-611-031; 036-581-744-446-721; 039-894-207-921-351; 045-773-286-957-382; 046-101-722-305-204; 047-492-079-663-789; 054-016-816-619-750; 054-637-023-743-470; 063-530-254-881-711; 071-554-807-246-766; 077-997-287-012-544; 081-235-454-701-552; 082-869-393-502-808; 085-285-853-007-905; 086-669-312-592-055; 091-002-133-977-086; 093-530-185-750-387; 096-849-706-918-207; 101-443-699-812-197; 106-907-585-611-260; 110-087-436-116-462; 120-218-131-901-312; 120-641-287-097-402; 126-149-422-402-099; 134-770-031-800-343; 141-705-183-829-973; 148-243-502-042-424; 169-872-683-676-883; 188-523-879-579-050; 199-748-751-862-574,199,true,cc-by,gold -061-630-144-399-065,Progress analysis of multi-dimensional perspective research on green ships: A knowledge graph-based approach.,2025-05-23,2025,journal article,Marine pollution bulletin,18793363; 0025326x,Elsevier BV,United Kingdom,Chunhui Zhou; Lin Jia; Wenjun Jia; Wuao Tang; Hongxun Huang; Lichuan Wu,,218,,118166,118166,Perspective (graphical); Graph; Graph theory; Computer science; Mathematics; Artificial intelligence; Theoretical computer science; Combinatorics,Bibliometric analysis; Emission reduction measures; Green ships; Knowledge graph,Ships; Bibliometrics; Conservation of Natural Resources,,Hubei Key Laboratory of Inland Shipping Technology; Science and Technology Department of Zhejiang Province; Innovative Research Group Project of the National Natural Science Foundation of China; National Natural Science Foundation of China,,http://dx.doi.org/10.1016/j.marpolbul.2025.118166,40412162,10.1016/j.marpolbul.2025.118166,,,0,000-123-777-813-802; 002-372-636-631-319; 003-426-307-006-94X; 006-401-697-060-308; 006-435-619-858-192; 008-351-257-700-498; 008-729-874-719-866; 009-915-708-607-549; 010-112-876-097-644; 012-010-104-004-204; 012-624-648-377-494; 013-031-525-347-976; 013-410-339-595-60X; 015-389-889-293-111; 019-695-723-093-110; 019-808-764-931-051; 021-465-423-176-182; 022-422-442-335-878; 023-918-069-164-26X; 025-315-922-516-710; 025-475-602-447-544; 026-373-480-072-148; 026-950-586-796-205; 028-127-310-339-793; 028-545-890-272-354; 029-080-353-289-379; 029-269-539-609-288; 029-562-903-485-73X; 030-362-122-059-622; 032-064-400-008-997; 037-906-020-029-18X; 037-934-685-536-555; 038-433-869-193-199; 040-274-330-979-303; 041-058-104-705-072; 041-809-145-249-071; 041-887-067-164-016; 046-992-864-415-70X; 047-800-572-559-362; 049-296-588-361-388; 049-636-948-868-421; 050-158-170-198-982; 050-580-083-605-707; 052-528-784-944-589; 054-695-767-483-419; 054-757-148-151-395; 055-526-534-270-438; 058-867-549-756-689; 065-909-839-598-152; 068-076-600-962-915; 069-193-541-456-770; 072-632-598-423-929; 073-272-420-653-620; 077-090-800-810-200; 082-153-897-031-997; 089-300-121-698-542; 090-244-849-972-200; 090-974-936-896-802; 091-732-548-746-508; 092-962-865-458-139; 093-291-928-293-899; 093-766-614-272-434; 094-741-540-555-823; 096-997-483-734-156; 097-633-029-961-227; 100-322-760-682-700; 103-115-275-097-062; 104-761-573-060-244; 108-700-685-752-583; 117-546-083-002-527; 120-241-780-570-440; 124-753-902-494-824; 125-322-196-981-423; 126-377-477-387-919; 128-317-355-894-590; 131-360-699-687-917; 135-273-142-159-850; 138-281-106-981-731; 139-749-460-369-227; 141-646-050-990-66X; 144-873-137-931-952; 146-674-141-791-009; 147-487-451-512-311; 151-801-480-679-652; 152-230-933-146-921; 157-563-563-552-048; 157-779-698-792-666; 165-313-479-215-792; 165-766-155-627-936; 169-791-557-965-049; 174-601-699-461-883; 176-443-165-998-75X; 179-003-962-231-973; 179-178-727-352-286,0,false,, -061-933-527-888-024,"Researches of ""Teaching and Learning on ESD"" Over the Last Two Decades: Bibliometric Analysis",2025-06-20,2025,journal article,KnE Social Sciences,2518668x,Knowledge E DMCC,,Duhita Savira Wardani; Ari Widodo; Ernawulan Syaodih; Muslim Muslim,"This study aims to provide an overview of ‘teaching and learning on ESD’ research in terms of scientific production, preferred publication venues, most involved researchers and countries (including collaborations). Data collection was done by extracting articles from Scopus online database system. The output was exported in BibTex format and was converted to a data frame through a function in bibliometrix. The main findings point to a continuous increase in research output in the field ‘teaching and learning on ESD’ over the last two decades. Furthermore, they indicate a shift regarding the research foci. While formerly mainly papers on the ESD were published, recently, an increase in the relevancy of empirical studies on the ‘teaching and learning on ESD’ can be observed. However, this study only focused on articles published in scientific journals so that future studies can also consider other sources books or conference proceedings.",10,12,193,202,,,,,,,http://dx.doi.org/10.18502/kss.v10i12.18890,,10.18502/kss.v10i12.18890,,,0,002-052-422-936-00X; 004-469-874-285-726; 007-446-858-302-247; 013-036-459-766-242; 013-507-404-965-47X; 014-109-112-361-298; 015-765-591-966-949; 017-750-600-412-958; 023-693-117-454-372; 028-183-619-231-293; 030-671-248-846-321; 032-199-352-187-684; 033-895-017-649-883; 034-076-781-085-144; 035-929-291-859-117; 037-687-151-120-349; 037-815-640-424-494; 042-899-919-930-716; 046-992-864-415-70X; 047-134-478-431-993; 047-697-021-908-260; 054-359-241-584-503; 060-110-039-971-60X; 063-867-989-846-259; 064-072-689-268-44X; 066-213-200-362-852; 071-360-540-979-630; 079-278-714-415-834; 086-390-755-607-801; 088-844-199-140-417; 090-874-327-921-285; 108-089-309-820-622; 110-351-458-836-866; 117-809-438-956-998; 124-756-681-728-378; 141-999-962-369-589; 161-585-107-816-013; 171-317-491-414-212; 174-416-286-160-631; 190-878-941-052-79X,0,false,, -062-030-560-637-146,Preprocesamiento de publicaciones acerca de indentidad digital descentralizada y autgobernada.,2022-01-01,2022,dataset,Figshare,,,,Roberto Pava,Referencias en formato bibtex obtenidas de las bases de datos Scopus y WoS. Preprocesamiento con el paquete bibliometrix,,,,,Humanities; Computer science; Philosophy,,,,,https://figshare.com/articles/dataset/Referencias_sobre_SSI_obtenidas_en_formato_bibtex/19579492/7,http://dx.doi.org/10.6084/m9.figshare.19579492.v7,,10.6084/m9.figshare.19579492.v7,,,0,,0,true,cc-by,gold -062-158-255-517-239,YouTube as an educational tool: insights from a scientific analysis,2024-12-29,2024,journal article,Cadernos de Educação Tecnologia e Sociedade,23169907,"Brazilian Journal of Education, Technology and Society (BRAJETS)",,Odorico Guilherme Veloso da Silva; Marcus Vinícius Carvalho Guelpeli; Weslley Luiz Da Silva Assis; Valnides Araújo da Costa,"This article investigates the use of YouTube as an educational tool through bibliometric analysis. Using the PRISMA 2020 guidelines, the research identified and screened 1,660 publications on the topic, extracted from the Scopus and Web of Science databases, covering the period from 2005 to 2024. The analysis was carried out using the RStudio software together with the Bibliometrix library and revealed a significant growth in scientific production related to the intersection between YouTube and education, highlighting keywords such as “learning”, “students” and “videos”. In addition, collaborations between authors and institutions were identified, as well as the evolution of research themes over time. The results show that YouTube maintains a central and growing position as an educational resource, reflecting the maturation of research in the area, and provides insights for educators and researchers into the potential of YouTube in the educational context, allowing for a better understanding of trends and collaborations in the use of videos as pedagogical tools.",17,4,1444,1459,Data science; Computer science; Psychology,,,,,,http://dx.doi.org/10.14571/brajets.v17.n4.1444-1459,,10.14571/brajets.v17.n4.1444-1459,,,0,,0,true,,gold -062-444-905-860-459,An Exploratory Analysis of the Scientific Production on Crowdfunding,,2024,journal article,New Challenges in Accounting and Finance,27178722,EUROKD Egitm Danismanlik Group,,João Guilherme Magalhães Timotio; Roberto César de Faria e Silva; Ramon Alves de Oliveira; Vânia Ereni Lima Vieira,"This study presents an exploratory analysis of the scientific production on crowdfunding, covering the period from 2010 to 2023. Utilizing data collected from the SciVerse Scopus database and analyzed with the Bibliometrix package, the research described the temporal evolution of publications, identified the most cited articles, and explored research networks through ""Clustering by Coupling."" The results show a significant increase in the number of publications on crowdfunding, especially after 2015, reflecting growing academic interest and the relevance of this financing method. The analysis identified three main clusters: crowdfunding and investments, business development and capital markets, crowdsourcing decision-making, and empirical analysis. These findings highlight the diversity and interdisciplinary collaboration within the field. The study concludes that crowdfunding not only democratizes access to capital but also promotes innovation and the building of supportive communities, making it an essential tool for modern entrepreneurship.",11,,14,28,Production (economics); Exploratory analysis; Business; Data science; Computer science; Economics; Microeconomics,,,,,,http://dx.doi.org/10.32038/ncaf.2024.11.02,,10.32038/ncaf.2024.11.02,,,0,,0,false,, -062-467-280-319-815,"Towards Supply Chain 5.0: Redesigning Supply Chains as Resilient, Sustainable, and Human-Centric Systems in a Post-pandemic World",2023-07-29,2023,journal article,Operations Research Forum,26622556,Springer Science and Business Media LLC,,Alice Villar; Stefania Paladini; Oliver Buckley,"AbstractThe purpose was to investigate the impact of the Industry 5.0 paradigm on the supply chain research field. Our study contributes to the conceptualization of supply chain 5.0, a term that has been receiving increased attention as supply chains adapt to the fifth industrial revolution. We conducted a systematic literature network analysis (SLNA) to examine the research landscape of Industry 5.0 supply chains. We used VOSViewer software and Bibliometrix R-package for multiple bibliometric analyses using 682 documents published between 2016 and 2022. We present a comprehensive framework of supply chain 5.0, including its key concepts, technologies, and trends. Additionally, this research offers a future research agenda to inspire and support further development in this field. We utilized three academic databases for bibliometric analyses: Dimension, Scopus and Lens. Additional databases could provide a wider research landscape and better field representation. We demonstrate how Industry 5.0 enables supply chain evaluation and optimization to assist companies in navigating disruptions without compromising competitiveness and profitability and provide a unique contribution to the field of supply chain 5.0 by exploring promising research areas and guiding the transition to this new paradigm for practitioners and scholars.",4,3,,,Supply chain; Supply chain management; Conceptualization; Field (mathematics); Scopus; Process management; Knowledge management; Bibliometrics; Business; Computer science; Marketing; Political science; Mathematics; MEDLINE; Artificial intelligence; Pure mathematics; Law; Data mining,,,,,https://link.springer.com/content/pdf/10.1007/s43069-023-00234-3.pdf https://doi.org/10.1007/s43069-023-00234-3,http://dx.doi.org/10.1007/s43069-023-00234-3,,10.1007/s43069-023-00234-3,,,0,002-995-208-654-267; 004-825-993-850-685; 005-553-722-664-274; 006-082-033-375-192; 006-381-532-148-883; 008-092-872-335-265; 008-271-422-618-915; 009-673-955-016-448; 010-851-355-868-035; 012-778-342-347-913; 013-061-078-739-800; 013-972-343-435-187; 014-041-363-512-54X; 016-819-194-616-838; 017-415-713-662-955; 017-714-406-684-732; 018-578-353-191-768; 019-611-972-958-014; 020-504-531-742-930; 021-152-254-601-282; 021-929-537-187-077; 023-085-075-503-121; 024-980-639-709-684; 025-055-813-171-364; 025-375-724-158-937; 026-122-683-001-052; 027-194-470-119-742; 029-173-073-052-054; 029-434-241-679-095; 033-851-018-944-660; 035-677-068-786-367; 036-513-534-472-185; 036-580-129-411-83X; 037-830-455-620-78X; 039-709-279-022-980; 039-957-070-894-668; 043-895-379-191-833; 044-998-373-851-683; 046-221-256-075-961; 046-446-925-840-307; 046-761-370-284-967; 047-344-167-153-151; 048-092-008-205-493; 049-816-999-056-296; 050-317-784-182-200; 050-400-202-276-950; 052-603-569-095-390; 053-804-731-130-455; 054-957-936-128-82X; 055-995-844-178-276; 057-214-042-880-707; 058-264-021-351-517; 058-435-708-506-507; 059-424-427-267-469; 064-138-810-036-202; 067-843-116-643-056; 067-975-723-728-662; 068-249-176-115-17X; 070-558-536-174-423; 070-609-833-244-587; 071-183-080-759-260; 073-362-963-306-077; 074-473-632-503-437; 081-356-950-648-149; 081-561-674-130-249; 083-491-904-459-720; 083-608-958-244-975; 084-249-962-919-116; 089-836-567-472-906; 091-230-936-298-903; 091-709-205-030-967; 097-911-116-881-847; 105-047-674-786-309; 106-892-889-471-659; 108-795-022-531-530; 111-244-907-483-334; 113-702-941-837-472; 113-830-545-572-413; 121-891-824-749-09X; 122-100-646-208-858; 123-468-560-474-102; 123-677-915-522-89X; 125-035-331-464-946; 125-134-057-094-789; 125-795-343-058-314; 126-042-692-951-426; 129-461-404-099-044; 136-779-502-305-386; 136-991-211-434-805; 140-109-678-513-738; 142-998-026-914-988; 146-530-330-462-05X; 152-053-926-392-978; 152-707-246-845-89X; 161-327-350-003-82X; 161-725-759-783-52X; 167-090-539-907-932; 170-912-030-345-381; 173-989-857-453-959; 182-737-009-025-172; 184-553-837-300-965; 187-347-342-658-879,41,true,cc-by,hybrid -062-546-087-533-428,Bibliometric and visual analysis in the field of two-dimensions nano black phosphorus in cancer from 2015 to 2023.,2024-07-03,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Jing'an Huang; Ling Zhang; Boren Li; Yuanchu Lian; Xiaoxin Lin; Zonghuai Li; Bo Zhang; Zhongwen Feng,"This study aims to provide a comprehensive summary of the status and trends of Two-Dimensional Nano Black Phosphorus (2D nano BP) in cancer research from 2015 to 2023, offering insights for future studies. To achieve this, articles from the Web of Science database published between 2015 and 2023 were analyzed using R and VOSviewer software. The analysis included 446 articles, revealing a consistent increase in publication rates, especially between 2017 and 2019. China emerged as a leader in both publication volume and international collaborations. Prominent journals in this field included ACS Applied Materials & Interfaces and Advanced Materials, while key researchers were identified as Zhang Han, Tao Wei, and Yu Xuefeng. The analysis highlighted common keywords such as drug delivery, photothermal therapy, photodynamic therapy, and immunotherapy, indicating the major research focuses. The findings suggest that 2D nano BP holds significant promise in cancer treatment research, with a growing global interest. This study thus serves as a valuable reference for future investigations, providing a detailed analysis of the current state and emerging trends in this promising field.",15,1,260,,Black phosphorus; Zhàng; Field (mathematics); Cancer; China; Library science; Medicine; Computer science; History; Internal medicine; Archaeology; Materials science; Mathematics; Optoelectronics; Pure mathematics,Bibliometric analysis; Drug delivery; Immunotherapy; Nano black phosphorus; Photothermal therapy,,,,,http://dx.doi.org/10.1007/s12672-024-01104-y,38961044,10.1007/s12672-024-01104-y,,PMC11222346,0,002-169-806-136-035; 002-582-160-882-125; 003-045-683-566-917; 010-562-967-456-778; 015-149-765-926-535; 015-450-293-427-430; 018-840-985-682-697; 019-565-928-239-413; 019-835-042-029-414; 020-443-109-561-409; 021-775-110-365-621; 024-249-245-078-522; 024-395-683-057-110; 033-027-615-931-811; 033-697-543-989-83X; 037-704-753-924-282; 039-171-886-820-309; 041-910-360-555-238; 048-981-878-065-21X; 050-343-157-906-782; 051-577-592-937-290; 055-854-198-904-755; 061-262-213-540-151; 061-682-322-687-786; 063-609-785-726-317; 064-424-781-997-510; 064-440-228-750-328; 064-595-411-024-478; 064-866-417-051-727; 068-353-631-008-959; 069-341-177-109-60X; 069-854-944-534-193; 071-650-840-614-401; 074-530-375-750-346; 074-559-445-206-848; 075-997-772-876-765; 077-682-582-506-399; 078-343-766-222-69X; 080-946-813-113-037; 082-575-383-120-300; 085-101-118-556-677; 090-043-232-949-093; 092-181-253-089-780; 099-451-414-342-049; 107-483-302-885-238; 108-385-977-018-332; 115-743-619-564-369; 117-680-115-265-792; 118-250-334-807-957; 139-853-451-015-988; 144-243-241-443-418; 145-157-119-626-996; 151-434-234-266-228; 158-119-885-811-204; 158-314-536-897-779; 163-474-236-651-084; 177-374-284-350-921; 178-088-172-032-813; 180-942-609-942-45X,3,true,cc-by,gold -062-568-232-120-804,Global Trends in the Research Output on Sustainable Development Goals,2022-06-24,2022,book chapter,"Advances in Systems Analysis, Software Engineering, and High Performance Computing",23273453; 23273461,IGI Global,,Diksha Diksha; Rupak Chakravarty,"The chapter is a bibliometric analysis of research work published on the Sustainable Development Goals. The authors extracted relevant data from Scopus on 22 August 2020, which were subsequently analyzed using open-source software – Bibliometrix (an R package). They performed a textual query on Scopus for the title “Sustainable Development Goal” by selecting the 'Article Title' in the 'Documents' option for the period of 1996-2020 and retrieved 1872 documents from 865 sources. This study aims to identify the global trends in the SDG's scientific production over time with analysis covering various bibliometric indicators (i.e., sources, authors, and documents). Results reveal growth in research in SDGs in recent years, trending topics, most relevant sources, prolific authors in the field, validation of Lotka's law. The findings can assist future research in this field by providing a worldwide analytical overview of the SDGs. ",,,27,47,Scopus; Sustainable development; Data science; Field (mathematics); Bibliometrics; Open source; Work (physics); Computer science; Library science; Political science; Software; Engineering; Mathematics; MEDLINE; Mechanical engineering; Pure mathematics; Law; Programming language,,,,,,http://dx.doi.org/10.4018/978-1-6684-4225-8.ch002,,10.4018/978-1-6684-4225-8.ch002,,,0,010-065-762-504-134; 010-495-710-613-419; 013-787-680-635-644; 015-015-282-840-40X; 025-302-119-966-613; 033-127-677-566-360; 037-989-280-310-687; 038-631-624-874-022; 039-491-120-499-550; 044-433-387-676-857; 153-282-924-188-573,4,false,, -062-715-570-746-76X,Research visualization of Indian LIS research using VOSviewer and Bibliometrix,2021-11-16,2021,journal article,Library Hi Tech News,07419058,Emerald,United Kingdom,Nidhi Gupta; Rupak Chakravarty,"This study aimed to visualize the trend topics in the research area of library and information science (LIS) in India during 1989–2021.,The data was extracted from the Web of Science core collection database (WoSCC) database from 1989 to 2021. For creating the network visualization maps from the data, freely available softwares, VOSviewer (VV) and Biblioshiny (a Web-interface for bibliometrix), were used.,Results support the prediction that in the future, Indian LIS research will focus on areas such as deep learning, machine learning, artificial intelligence and block chain technology. Among the most prolific authors Satija, M.P (Guru Nanak Dev University, Amritsar) and Prathap, G (APJ Abdul Kalam Technology University) secured top positions in LIS research. Scientometric ranked the top journal or the core journal after applying Bradford law.,The visualization of trend topics in LIS research from 1989 to 2021, 32 years of time span, is the first of its kind.",38,8,6,8,Graph drawing; Library science; Political science; Visualization,,,,,https://www.emerald.com/insight/content/doi/10.1108/LHTN-10-2021-0076/full/html,http://dx.doi.org/10.1108/lhtn-10-2021-0076,,10.1108/lhtn-10-2021-0076,3212813594,,0,008-911-952-895-082; 056-486-394-182-18X; 115-943-088-513-875; 125-440-731-388-398; 134-384-482-367-395; 147-464-001-506-115; 165-490-953-437-112; 165-775-950-904-052,6,false,, -062-912-057-319-217,Exploring machine learning: a scientometrics approach using bibliometrix and VOSviewer.,2022-04-11,2022,journal article,SN applied sciences,25233971; 25233963,Springer Science and Business Media LLC,Switzerland,David Opeoluwa Oyewola; Emmanuel Gbenga Dada,"Machine Learning has found application in solving complex problems in different fields of human endeavors such as intelligent gaming, automated transportation, cyborg technology, environmental protection, enhanced health care, innovation in banking and home security, and smart homes. This research is motivated by the need to explore the global structure of machine learning to ascertain the level of bibliographic coupling, collaboration among research institutions, co-authorship network of countries, and sources coupling in publications on machine learning techniques. The Hierarchical Density-Based Spatial Clustering of Applications with Noise (HDBSCAN) was applied to clustering prediction of authors dominance ranking in this paper. Publications related to machine learning were retrieved and extracted from the Dimensions database with no language restrictions. Bibliometrix was employed in computation and visualization to extract bibliographic information and perform a descriptive analysis. VOSviewer (version 1.6.16) tool was used to construct and visualize structure map of source coupling networks of researchers and co-authorship. About 10,814 research papers on machine learning published from 2010 to 2020 were retrieved for the research. Experimental results showed that the highest degree of betweenness centrality was obtained from cluster 3 with 153.86 from the University of California and Harvard University with 24.70. In cluster 1, the national university of Singapore has the highest degree betweenness of 91.72. Also, in cluster 5, the University of Cambridge (52.24) and imperial college London (4.52) having the highest betweenness centrality manifesting that he could control the collaborative relationship and that they possessed and controlled a large number of research resources. Findings revealed that this work has the potential to provide valuable guidance for new perspectives and future research work in the rapidly developing field of machine learning.",4,5,143,,Betweenness centrality; Computer science; Centrality; Artificial intelligence; Cluster analysis; Scientometrics; Complex network; Machine learning; Construct (python library); Clustering coefficient; Big data; Cluster (spacecraft); Network science; Data science; Data mining; World Wide Web; Mathematics; Programming language; Combinatorics,Bibliometrix; Coupling; Machine learning; Scientometrics; VOSviewer,,,,https://link.springer.com/content/pdf/10.1007/s42452-022-05027-7.pdf https://doi.org/10.1007/s42452-022-05027-7,http://dx.doi.org/10.1007/s42452-022-05027-7,35434524,10.1007/s42452-022-05027-7,,PMC8996204,0,000-748-918-183-112; 002-052-422-936-00X; 004-350-064-169-354; 008-112-156-362-057; 008-826-453-129-213; 009-854-927-686-72X; 009-965-013-508-689; 013-507-404-965-47X; 015-562-502-380-664; 024-078-756-825-135; 024-113-667-116-661; 024-294-874-854-03X; 025-302-119-966-613; 026-214-660-581-435; 034-732-911-805-318; 035-550-954-905-684; 037-243-980-780-195; 037-907-112-181-167; 039-842-482-800-728; 044-176-003-785-436; 044-500-124-558-805; 053-570-663-810-918; 053-877-830-796-428; 062-541-212-644-205; 063-989-010-982-849; 065-176-191-098-124; 067-263-492-957-015; 072-475-866-686-308; 078-832-571-030-02X; 081-671-278-001-936; 089-719-663-022-259; 091-844-215-624-322; 092-274-926-085-614; 092-406-870-353-174; 095-727-071-343-144; 105-538-482-028-753; 119-854-188-262-453; 121-001-950-491-969; 138-613-801-688-797; 139-040-911-677-344; 150-041-771-100-369; 169-787-469-943-657; 186-922-752-185-914; 190-241-958-060-27X,82,true,cc-by,gold -062-968-443-156-586,Worldwide research progress and trends on geothermal water–rock interaction experiments: a comprehensive bibliometric analysis,2023-01-11,2023,journal article,Earth Science Informatics,18650473; 18650481,Springer Science and Business Media LLC,Germany,D. Yáñez-Dávila; E. Santoyo; G. Santos-Raga,"AbstractThe present work reports a novel methodological and comprehensive bibliometric analysis on past and present research advances carried out on geothermal water–rock interaction experiments from 1963 to 2022. The novel bibliometric analysis enabled the most representative bibliometric indicators on the research subject to be obtained. Published articles, preferred publication journals, research leaderships (authors, networking groups, institutions, and countries), and future research trends were also collected from a comprehensive searching carried out in indexed databases (Web of Science and Scopus). Up to our knowledge, this bibliometric information will benefit the worldwide geothermal community by providing a deeper insight of water/rock interaction lab experiments carried out up to date. The bibliometric analysis suggests relevant research areas such as geochemistry, thermodynamics, enhanced geothermal systems, carbon dioxide capture, and hydrothermal alteration as the main key research findings. These research areas were identified as the main bibliometric hotspots which have a strong potential to be used for the experimental design of new and improved water–rock interaction studies to address some crucial problems present in the geothermal prospection and exploitation. Among these problems stand out the study of hydrothermal, superhot and enhanced geothermal systems, the chemical fractionation of major and trace elements, the hydrothermal alteration, the calibration of solute and gas geothermometers, the scaling and corrosion problems, the carbon capture and storage, the evaluation of environmental issues, among others. Details of this comprehensive bibliometric analysis, including some statistical and text mining and mapping tools are fully outlined.",16,1,1,24,Geothermal gradient; Scopus; Earth science; Data science; Prospection; Bibliometrics; Computer science; Web of science; Environmental science; Library science; Geology; Geography; Archaeology; Political science; MEDLINE; Geophysics; Law,,,,CONACYT Scholarship Graduate Programme; CONACYT Scholarship Graduate Programme; Research Project UNAM DGAPA-PAPIIT,https://link.springer.com/content/pdf/10.1007/s12145-022-00926-0.pdf https://doi.org/10.1007/s12145-022-00926-0,http://dx.doi.org/10.1007/s12145-022-00926-0,,10.1007/s12145-022-00926-0,,,0,008-131-859-339-244; 008-962-921-400-817; 011-708-216-714-970; 011-813-956-412-702; 012-750-892-823-852; 013-507-404-965-47X; 017-750-600-412-958; 019-394-925-804-006; 020-076-034-746-238; 020-769-189-128-612; 021-286-115-169-972; 021-829-924-988-853; 022-050-154-142-786; 022-672-669-347-509; 024-413-302-435-197; 026-709-628-177-170; 029-454-142-788-550; 030-184-036-846-700; 032-391-355-302-342; 033-697-033-042-291; 034-732-911-805-318; 035-856-034-336-484; 036-086-618-929-126; 039-185-548-712-951; 041-339-568-185-168; 041-642-521-650-546; 042-199-465-750-114; 042-805-269-617-989; 042-812-073-522-57X; 043-974-063-033-279; 045-119-188-485-047; 045-173-752-152-890; 045-777-924-761-762; 046-282-677-763-024; 046-992-864-415-70X; 047-134-478-431-993; 048-048-513-620-93X; 051-071-986-316-827; 052-368-395-173-987; 053-279-243-710-984; 054-152-342-558-816; 056-760-282-429-634; 059-066-414-441-424; 060-419-014-764-634; 065-754-113-310-769; 066-133-112-740-761; 066-153-046-006-611; 067-156-456-566-750; 069-748-529-562-323; 070-665-150-453-490; 072-544-544-754-642; 073-765-320-681-988; 073-957-588-798-34X; 074-016-528-107-270; 075-939-282-420-567; 076-062-166-298-62X; 079-182-978-414-687; 082-336-486-164-631; 082-695-835-088-433; 083-052-765-266-579; 087-729-626-130-134; 087-898-379-953-009; 090-874-327-921-285; 091-968-582-634-420; 092-285-030-524-972; 095-819-145-586-586; 096-746-342-829-622; 098-377-939-800-955; 099-328-096-020-226; 099-594-220-920-187; 105-066-503-926-809; 112-722-639-517-939; 116-466-776-824-64X; 120-974-286-046-262; 133-106-741-363-780; 133-678-159-321-132; 133-822-448-390-04X; 134-366-982-952-006; 137-324-153-406-001; 155-920-037-214-911; 169-289-421-584-569; 170-119-832-458-827; 174-784-957-060-113; 178-016-403-210-11X; 181-590-600-481-386,3,true,cc-by,hybrid -063-040-409-938-363,Research trends in alopecia areata: a cross-sectional bibliometric analysis of the top cited studies.,2024-05-25,2024,journal article,Archives of dermatological research,1432069x; 03403696,Springer Science and Business Media LLC,Germany,Hui-Chin Chang; Tsu-Man Chiu; Chien-Ying Lee; Shiu-Jau Chen; Wen-Chieh Liao; Shuo-Yan Gau,,316,6,234,,Alopecia areata; Medicine; Epidemiology; Dermatology; Pathology,Alopecia areata; Bibliometric analysis; Dermatology; Immunology,Alopecia Areata/epidemiology; Humans; Bibliometrics; Cross-Sectional Studies; Janus Kinase Inhibitors/therapeutic use; Adrenal Cortex Hormones/therapeutic use; Biomedical Research/trends,Janus Kinase Inhibitors; Adrenal Cortex Hormones,,,http://dx.doi.org/10.1007/s00403-024-03092-z,38795240,10.1007/s00403-024-03092-z,,,0,003-994-293-244-271; 008-961-251-634-440; 013-507-404-965-47X; 030-879-261-513-292; 039-699-368-413-725; 043-556-369-169-855; 049-538-053-034-523; 051-747-163-182-896; 053-819-393-888-58X; 054-527-727-095-208; 057-916-959-114-453; 064-210-655-833-36X; 068-097-574-029-373; 081-212-797-729-15X; 086-953-799-653-427; 101-180-023-228-124; 105-644-998-923-926; 110-960-706-192-064; 150-938-462-455-875; 196-757-735-107-080,2,false,, -063-820-967-924-772,Islamic Business Ethics Research in Google Scholar Using Bibliometrix Analysis,2025-04-19,2025,journal article,Asian Journal of Islamic Studies and Da'wah,30254493; 30255252,Darul Yasin Al Sys,,A Syathir Sofyan; Ummy Aisyah Arsyad; Hismayanti Aprilia; Nurandini Putri,"This research aims to see the development trend of Islamic business ethics studies in the scope of business and management published in Shinta indexed journals. This research uses bibliometric method with R Studio analysis tool which is used to analyse bibliographic data obtained automatically. The results showed that the number of Islamic business ethics publications has increased along with the number of Muslim entrepreneurs who apply Islamic business ethics in their business processes. The results of bibliometric analysis found that Islamic business ethics research is dominated by Islamic business ethic and ethic which uses more quantitative approaches. Furthermore, some research themes that can develop in the future are themes related to Product Quality Issue and Service Quality Issue. This study contributes to future research and provides scientific novelty in the assessment of Islamic business ethics publications in the scope of business and management and is also practically and theoretically very important for academics.",3,3,313,331,Islam; Business ethics; Sociology; Political science; Philosophy; Public relations; Theology,,,,,,http://dx.doi.org/10.58578/ajisd.v3i3.5429,,10.58578/ajisd.v3i3.5429,,,0,,0,false,, -063-829-269-453-724,Deliberately Causing Brand Confusion: State of the (Unfair) Art,2022-02-02,2022,journal article,Business Perspectives and Research,22785337; 23949937,SAGE Publications,,Anurag Dugar; Y. L. R. Moorthi," Brand Confusion is a time-worn yet highly relevant topic for marketers, researchers, and regulatory agencies because colossal and ever-increasing number of legal cases on brand confusion have kept them interested in it. This study aims to provide a commentary on worldwide scientific literature on brand confusion highlighting the evolution, advances, trends, and inter-connections. For this purpose, 200 documents on brand confusion published between 1985 and 2019 have been systematically reviewed using Bibliometrix, a software based on R Studio. This study contributes by presenting a snapshot of the extant research on brand confusion and by providing useful insights for practitioners and researchers in terms of managerial implications and directions for further research. This is the first study to explore a wide range of global interdisciplinary scholarly work on brand confusion and its causes. ",11,1,112,136,Confusion; Extant taxon; Snapshot (computer storage); Psychology; Computer science; Evolutionary biology; Psychoanalysis; Biology; Operating system,,,,,,http://dx.doi.org/10.1177/22785337211070380,,10.1177/22785337211070380,,,0,005-189-118-087-716; 008-417-185-917-514; 013-008-017-051-399; 016-715-269-424-974; 022-436-064-953-501; 024-623-882-254-24X; 026-101-973-894-167; 028-515-333-229-145; 030-060-526-482-917; 032-801-963-434-196; 038-965-362-971-85X; 052-236-505-160-155; 054-360-531-267-002; 054-818-565-070-154; 060-555-562-627-020; 062-068-976-038-044; 070-308-340-373-162; 071-463-469-373-59X; 080-436-406-243-416; 093-705-600-965-572; 105-483-505-774-420; 116-648-740-405-846; 118-606-875-362-289; 120-612-440-909-292; 141-641-322-260-255; 155-424-392-181-39X; 165-972-094-523-726; 169-789-443-277-245; 188-872-401-663-996,2,false,, -063-993-989-101-318,Innovativeness: a bibliometric vision of the conceptual and intellectual structures and the past and future research directions,2020-11-03,2020,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Danilo Magno Marchiori; Silvio Popadiuk; Emerson Wagner Mainardes; Ricardo Gouveia Rodrigues,,126,1,55,92,Sociology; Set (psychology); Sociology of scientific knowledge; Data science; Theme (narrative); Bibliographic coupling; Context (language use); Scientific literature; Field (computer science); Business studies,,,,This Brazilian National Council for Scientific and Technological Development; Fundação Estadual de Amparo à Pesquisa do Estado do Espírito Santo; Portuguese Science Foundation (FCT/Portugal) through NECE; IFTS,https://link.springer.com/article/10.1007/s11192-021-03994-z https://doi.org/10.1007/s11192-021-03994-z https://www.scilit.net/article/100ef6aa9b6b86653703da764ab2751b?action=show-references https://EconPapers.repec.org/RePEc:spr:scient:v:126:y:2021:i:11:d:10.1007_s11192-021-03994-z https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics126.html#MarchioriPMR21 https://link.springer.com/content/pdf/10.1007/s11192-021-03994-z.pdf https://ideas.repec.org/a/spr/scient/v126y2021i1d10.1007_s11192-020-03753-6.html,http://dx.doi.org/10.1007/s11192-020-03753-6,,10.1007/s11192-020-03753-6,3095186218,,0,000-304-520-410-330; 001-301-285-510-325; 002-052-422-936-00X; 007-644-763-272-249; 007-668-566-281-898; 008-316-360-961-65X; 008-719-533-743-594; 009-604-238-587-994; 010-107-154-303-614; 011-153-571-890-753; 012-148-170-366-782; 013-507-404-965-47X; 013-524-854-219-241; 013-843-007-145-26X; 014-554-658-257-770; 015-694-820-098-511; 015-785-917-851-665; 015-944-214-615-258; 016-522-727-431-442; 016-647-879-582-53X; 016-754-158-777-250; 016-832-003-735-76X; 017-557-569-036-776; 017-750-600-412-958; 018-141-003-730-539; 018-391-667-712-458; 018-697-973-926-51X; 020-067-709-218-691; 020-434-133-855-445; 021-978-185-408-18X; 022-409-041-490-686; 023-560-725-367-265; 023-790-968-473-402; 023-884-258-621-287; 023-927-221-065-800; 024-147-652-285-732; 024-351-685-506-472; 025-216-749-290-709; 025-822-212-900-01X; 026-169-050-342-031; 027-656-693-450-137; 027-902-084-418-909; 032-344-448-641-51X; 032-436-144-280-645; 032-677-286-156-639; 033-824-212-334-459; 033-845-387-725-390; 034-085-708-554-690; 034-211-392-123-492; 035-516-703-307-779; 036-180-306-579-957; 036-181-747-472-359; 037-036-602-845-527; 038-450-264-768-329; 039-071-884-757-993; 040-269-460-422-291; 040-533-906-540-111; 041-839-775-330-445; 042-122-399-049-729; 046-731-703-794-213; 046-758-542-260-105; 046-761-915-521-169; 046-881-709-065-39X; 047-134-478-431-993; 047-965-709-104-71X; 048-463-136-923-246; 049-862-761-557-055; 050-426-592-797-57X; 051-318-198-455-748; 053-295-670-541-193; 053-686-629-143-917; 053-939-921-897-479; 054-344-263-957-321; 054-438-650-544-751; 054-512-588-964-669; 054-818-565-070-154; 055-955-083-149-713; 056-251-168-822-453; 057-058-693-769-402; 058-298-653-779-349; 060-110-039-971-60X; 061-080-555-341-243; 061-802-630-654-699; 062-018-515-734-236; 062-104-602-914-252; 064-502-002-687-988; 064-806-594-040-960; 064-898-494-697-587; 066-140-281-101-376; 066-858-470-188-282; 067-648-153-879-929; 070-125-454-505-213; 072-844-799-889-738; 073-208-462-239-093; 073-407-528-215-740; 075-006-135-906-490; 075-185-867-665-078; 075-432-791-330-698; 076-588-608-352-213; 077-126-410-927-034; 077-415-958-756-69X; 077-534-620-134-537; 079-449-803-054-026; 083-018-376-971-259; 083-814-640-298-727; 085-152-071-030-482; 085-300-287-100-525; 086-404-609-880-919; 089-621-912-811-772; 090-759-739-502-42X; 092-618-090-415-439; 095-498-445-632-543; 097-165-190-008-69X; 097-505-245-032-987; 097-506-102-238-114; 099-553-222-496-956; 100-294-259-882-658; 105-021-657-753-42X; 105-221-629-947-856; 107-289-744-406-143; 108-045-597-745-991; 109-546-326-859-163; 111-421-985-054-900; 114-656-816-592-957; 116-138-261-772-577; 118-419-501-591-315; 119-753-365-840-574; 125-812-694-825-484; 128-808-033-158-896; 132-305-655-707-976; 133-000-203-710-102; 139-101-567-335-455; 139-719-817-508-510; 143-777-543-486-085; 146-897-496-073-557; 148-387-011-801-708; 149-099-635-859-414; 150-087-607-249-413; 151-675-158-631-891; 151-681-790-455-749; 153-347-070-690-416; 155-100-462-854-182; 163-339-003-682-996; 164-319-369-995-637; 168-036-345-097-619; 169-400-792-580-308; 171-611-534-360-451; 175-801-845-178-844; 176-791-655-648-833; 179-608-372-698-452; 186-694-932-124-180; 192-389-272-784-584,31,false,, -064-061-860-284-244,ANALYSIS OF PUBLICATION ACTIVITY IN THE FIELD OF MANAGEMENT PROCESSES IN THE LOGISTICS SYSTEM BASED ON THE RUSSIAN SCIENTIFIC CITATION INDEX AND THE SCOPUS DATABASE,,2022,journal article,System analysis and logistics,20775687,State University of Aerospace Instrumentation (SUAI),,D. V. Kalakutskaya; S. V. Ugolkov,"In this article the work in the program VOSviewer and the performance of scientometric analysis on the basis of the data of publications in Scopus. The scientometric analysis performed in the software system BIBLIOMETRIX. The scientometric analysis allows to determine the key articles, in which the most important scientific articles and publications in the field of logistics and supply chains are presented. The results of research in the field of management processes in logistics systems have been analyzed. The ranking of the publications by significance in the ratings (quartiles Q1, Q2, Q3, Q4) has been performed. The analysis of publication intensity is performed and the key authors and names of the articles with the highest citations are presented.",2,32,3,14,Scopus; Ranking (information retrieval); Field (mathematics); Quartile; Computer science; Index (typography); Key (lock); Citation analysis; Bibliometrics; Citation; Information retrieval; Data science; Library science; World Wide Web; Political science; Statistics; Mathematics; MEDLINE; Pure mathematics; Law; Confidence interval; Computer security,,,,,,http://dx.doi.org/10.31799/2077-5687-2022-2-3-14,,10.31799/2077-5687-2022-2-3-14,,,0,,0,false,, -064-295-582-053-674,Bibliometrix Data for Residual Agroforest Biomass.xlsx,2023-01-01,2023,dataset,Figshare,,,,Prabalta Rijal,"This database is a compilation of the data downloaded from Scopus and WebofScience, for a systematic literature review on the drivers and barriers of Residual Agroforestry Biomass Valorization. This database contains 194 documents which was also used for a bibliometric study of the available literature.",,,,,Residual; Biomass (ecology); Environmental science; Geology; Mathematics; Algorithm; Oceanography,,,,,https://figshare.com/articles/dataset/Bibliometrix_Data_for_Residual_Agroforest_Biomass_xlsx/22213666,http://dx.doi.org/10.6084/m9.figshare.22213666,,10.6084/m9.figshare.22213666,,,0,,0,true,cc-by,gold -064-420-800-037-200,Global research and current trends on nanotherapy in lung cancer research: a bibliometric analysis of 20 years.,2024-10-09,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Pooja Singh; Prabhakar Semwal; Baby Gargi; Sakshi Painuli; Michael Aschner; Khalaf F Alsharif; Haroon Khan; Rakesh Kumar Bachheti; Limenew Abate Worku,"Lung cancer ranks as one of the most rapidly growing malignancies. Which is characterized by its poor prognosis and a low survival rate due to late diagnosis and limited efficacy of conventional treatments. In recent years nanotechnology has emerged as a promising frontier in the management of lung cancer, presenting novel strategies to enhance drug administration, improve therapeutic efficiency, and mitigate side effects. This research comprehensively evaluates the current state and research trends concerning the application of nanomaterials in lung cancer through bibliometric analysis.; We employed a systematic approach by retrieving studies from the Scopus database that focused on nanomaterials and lung cancer between 2003 and 2023. Subsequently, we carefully selected relevant articles based on predetermined inclusion criteria. The selected publications were then subjected to bibliometric and visual analysis using softwares such as VOSviewer and Biblioshiny.; A total of 3523 studies that meet inclusion criteria were selected for bibliometric analysis. We observed a progressive increase in the number of annual publications from 2003 to 2023, indicating the growing interest in this field. According to our analysis, China is the primary contributor to publication output among the countries. The ""Ministry of Education of the People's Republic of China"" was the most influential institution. Among the authors, ""Dr. Jack A. Roth"" and ""Dr. Huang Leaf"" had the highest number of publications and cited publications, respectively. The ""International Journal of Nanomedicine"" was found to be the most prolific journal in this field. Additionally, ""Biomaterials"" emerged as the most cited journal. Through keyword analysis, we identified five main research themes and future research directions; nono-immunotherapy and green synthesis are the hot topics in this research field.; Our study summarized the key characteristics of publications in this field and identified the most influential countries, institutions, authors, journals, hot topics, and trends related to the application of nanomaterials in lung cancer. These findings contribute to the existing body of knowledge and serve as a foundation for future research endeavors in this area. More effective efforts are needed in this field to reduce the burden of lung cancer and help achieve the United Nation's Sustainable Development Goals.; © 2024. The Author(s).",15,1,539,,Lung cancer; Bibliometrics; Medicine; Political science; Regional science; Environmental health; Library science; Geography; Oncology; Computer science,Bibliometric analysis; Lung cancer research; Nanomaterials; Scopus database,,,,,http://dx.doi.org/10.1007/s12672-024-01332-2,39384612,10.1007/s12672-024-01332-2,,PMC11465009,0,000-614-259-137-548; 002-052-422-936-00X; 002-141-840-956-34X; 002-597-131-023-630; 004-516-471-525-982; 004-587-784-314-201; 005-198-779-150-932; 006-185-472-961-822; 008-100-113-674-829; 009-517-251-237-985; 010-141-204-952-305; 010-585-649-208-113; 014-645-855-219-064; 020-080-046-935-409; 020-919-018-249-867; 022-374-545-534-673; 024-278-091-969-148; 030-322-364-953-655; 033-155-400-338-136; 034-768-039-318-254; 042-104-849-405-702; 042-687-911-387-646; 042-769-629-291-869; 044-930-790-682-058; 045-117-367-995-465; 046-348-322-094-721; 046-992-864-415-70X; 054-091-120-945-89X; 055-497-099-256-606; 056-927-513-939-853; 057-142-544-603-195; 057-918-133-578-656; 061-449-736-687-339; 062-828-179-776-908; 062-844-619-807-043; 063-073-946-403-701; 063-933-889-527-528; 067-777-082-467-193; 068-458-313-571-026; 069-552-726-026-218; 069-640-677-843-309; 071-878-836-294-733; 073-059-082-690-329; 078-091-781-068-135; 080-396-666-471-374; 083-241-261-298-748; 084-179-877-825-51X; 086-883-572-942-426; 087-372-459-420-855; 091-251-371-132-713; 098-361-839-518-841; 099-650-256-973-997; 100-609-227-350-394; 101-752-490-869-458; 102-466-792-432-621; 104-783-899-955-969; 107-262-715-167-286; 109-742-365-993-865; 110-254-438-847-184; 112-487-623-021-691; 118-110-056-288-215; 118-960-257-415-437; 125-075-658-185-419; 126-959-051-411-977; 128-662-344-618-256; 144-757-510-844-681; 144-958-770-344-924; 147-374-503-041-056; 147-525-361-096-160; 151-911-919-999-976; 161-446-181-958-191; 164-662-083-556-83X; 166-141-504-630-41X; 170-074-345-687-220; 194-281-809-822-869,2,true,cc-by,gold -064-921-167-248-349,ANALISIS BIBLIOMETRIX PERAN PEREMPUAN DALAM PENDIDIKAN ISLAM PADA DATABASE SCOPUS TAHUN 2012-2022,2023-02-28,2023,journal article,Tarbiyatuna Kajian Pendidikan Islam,26221942; 25974807,Institut Agama Islam Ibrahimy Genteng Banyuwangi,,Ulfatun Naili Nadhiroh; Abdul Halim; Syahrul Ramadhan,"This study aims to analyze research trends related to the role of women in Islamic education in various parts of the world which were published through the Scopus database from 2012 to 2022. This study used quantitative research methods with bibliometric analysis using R-Packages software and WebInterface Biblioshiny for analysis. and data visualization. The keywords used are 'Islamic Education', and 'Women', to generate more specific data searches with research theme categories. Based on the search results, the researcher obtained 674 scientific papers, which the authors specified using only two types of documents, namely articles and conference papers, resulting in 279 documents. The results of the study show that the theme of the role of women in Islamic education still attracts attention for research to date, even though it fluctuates every year. The most influential publication is research conducted by Noorbala A entitled ""Mental Health Survey of The Iranian Adult Population in 2015"". His work published in 2017 has been cited 106 times. While the most affiliation is Shahid Beheshti University of Medical Sciences with 21 publications and the most productive country with the highest number of citations is Iran with 261 citations. It is hoped that this trend-related analysis on the theme of the role of women in Islamic education can be used as a reference for further research.",7,1,102,102,Scopus; Political science; Islam; Philosophy; Theology; MEDLINE; Law,,,,,,http://dx.doi.org/10.69552/tarbiyatuna.v7i1.1840,,10.69552/tarbiyatuna.v7i1.1840,,,0,,0,false,, -064-967-946-043-629,Form and typology: systematic review in architectural publications,2024-06-14,2024,preprint,,,MDPI AG,,Francisco Vergara-Perucich,"This paper presents a comprehensive bibliometric analysis of research on form and typology in architectural publications, spanning from 1999 to 2024. Utilizing the Web of Science database and the bibliometrix package in R, the study examines trends, influential works, and thematic evolution in the field. The findings reveal a progression from foundational themes such as ""architecture,"" ""culture,"" and ""planning"" to more specialized and diverse topics, including ""sustainability,"" ""parametric design,"" and ""digital fabrication."" Key influential works by authors like Jane Jacobs, Kevin Lynch, and Bill Hillier are highlighted. The study also underscores the collaborative nature of contemporary architectural research, with significant international co-authorship. While providing valuable insights into the research landscape, the study acknowledges limitations, such as database reliance and the need for qualitative analysis. The paper concludes with recommendations for future research, emphasizing the exploration of emerging technologies, interdisciplinary collaborations, and regional research dynamics.",,,,,Typology; Political science; Sociology; Anthropology,,,,,,http://dx.doi.org/10.20944/preprints202406.0928.v1,,10.20944/preprints202406.0928.v1,,,0,,0,true,,green -065-114-931-023-061,Entrepreneurial self-efficacy among students: a bibliometric mapping and topic modelling approach,2025-02-27,2025,journal article,Entrepreneurship Education,25208144; 25208152,Springer Science and Business Media LLC,,Stuwart Anton; Paul Mansingh,,8,2,177,203,Bibliometrics; Computer science; Psychology; Mathematics education; Data science; Library science,,,,,,http://dx.doi.org/10.1007/s41959-025-00138-9,,10.1007/s41959-025-00138-9,,,0,003-641-846-041-084; 004-505-636-199-65X; 004-642-028-699-897; 011-715-072-310-189; 012-649-121-140-627; 013-422-282-868-950; 013-507-404-965-47X; 014-654-872-345-665; 014-706-773-571-431; 015-227-299-935-573; 015-692-170-714-052; 016-088-587-457-915; 016-402-202-999-805; 017-424-740-724-909; 018-055-138-250-187; 024-152-516-154-881; 025-220-598-896-579; 033-314-857-336-240; 039-594-661-223-727; 040-266-796-379-174; 042-675-225-958-930; 044-776-532-451-668; 046-992-864-415-70X; 050-609-067-982-963; 051-153-163-883-862; 051-391-316-574-010; 053-962-480-776-641; 053-982-600-107-724; 057-333-698-666-115; 059-237-549-812-759; 059-702-698-076-442; 059-956-033-421-432; 060-784-290-267-429; 061-890-760-155-735; 066-558-013-585-616; 067-056-471-697-275; 067-149-221-819-121; 073-637-689-214-814; 079-589-662-275-566; 080-294-980-130-298; 082-244-574-703-49X; 082-600-152-539-798; 091-148-928-443-370; 093-684-458-504-395; 094-021-263-172-414; 106-864-470-895-286; 113-682-442-621-962; 114-404-210-919-547; 115-973-304-180-241; 118-629-757-350-959; 120-040-888-268-779; 124-319-041-152-07X; 124-683-499-926-517; 126-609-927-349-873; 127-837-920-677-63X; 141-084-332-398-603; 141-139-507-543-856; 141-205-450-645-984; 146-373-502-039-05X; 149-286-103-734-112; 180-907-636-144-054; 182-355-485-360-576; 186-581-776-671-906; 194-602-145-848-744; 197-137-698-286-84X,0,false,, -065-123-395-775-669,The comparative landscape of Chinese and foreign articles on the carbon footprint using bibliometric analysis.,2022-01-20,2022,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Rong Wu; Yundong Xie; Yezhu Wang; Zhi Li; Li Hou,,29,23,35471,35483,Carbon footprint; Footprint; Greenhouse gas; Web of science; Citation analysis; Bibliometrics; Citation; Chinese academy of sciences; Regional science; China; Political science; Computer science; Sociology; Geography; Library science; MEDLINE; Ecology; Biology; Archaeology; Law,Bibliometric analysis; Carbon footprint; Chinese articles; Citation analysis; Foreign articles,"Bibliometrics; Carbon Footprint; China; Databases, Factual; Internationality",,,,http://dx.doi.org/10.1007/s11356-022-18493-8,35050474,10.1007/s11356-022-18493-8,,,0,000-420-785-929-97X; 001-421-585-340-184; 002-362-089-067-034; 007-239-927-791-506; 008-047-541-440-500; 008-251-874-383-397; 008-626-278-999-820; 011-990-236-581-02X; 013-507-404-965-47X; 013-524-854-219-241; 014-224-712-455-136; 014-361-296-611-814; 016-379-263-010-260; 017-503-105-702-677; 018-899-704-235-169; 019-137-128-057-493; 021-925-953-306-786; 023-083-174-136-604; 028-894-371-422-248; 029-358-529-683-913; 030-387-975-251-174; 033-101-662-418-618; 033-663-874-369-875; 035-175-029-481-51X; 037-541-330-879-877; 041-100-312-257-67X; 045-850-749-322-866; 048-091-144-025-222; 049-692-040-196-115; 051-161-098-686-351; 053-768-168-301-546; 054-279-510-458-565; 054-831-903-718-002; 055-767-576-999-945; 059-546-291-641-495; 059-610-131-267-653; 062-551-341-053-072; 064-400-499-357-900; 074-878-148-711-475; 077-498-268-655-601; 085-323-782-918-844; 089-278-425-558-516; 089-648-343-086-143; 091-120-913-247-700; 097-098-960-848-891; 097-875-158-386-515; 098-183-188-079-005; 100-136-492-238-38X; 101-752-490-869-458; 101-817-428-036-644; 106-813-425-460-013; 107-449-289-643-453; 108-993-599-275-065; 114-854-687-455-944; 120-223-057-117-373; 120-491-048-858-007; 127-510-826-999-160; 131-684-077-588-800; 134-117-644-965-034; 141-764-266-513-704; 149-587-631-377-488; 151-067-592-580-151; 164-602-814-206-59X; 189-822-032-455-278,11,false,, -065-565-665-887-088,Mapping the Waves: A Bibliometric Analysis of Stock Market Volatility,2023-07-28,2023,journal article,Journal of Law and Sustainable Development,27644170,Brazilian Journals,,Debanjalee Bose; Kandaswamy Sakthi Srinivasan,"Purpose: The main Objective of the study is to identify the trends of stock market volatility based on previous research from 2012 to 2022 by performing a bibliometric analysis.;  ; Theoretical framework: The study aims to identify the key authors, countries, institutions, and top-cited journals in the specific area. The study reveals a considerable increase in the number of publications on stock market volatility which depicts the growing interest of the researcher to study and explore more new trends in this area;  ; Design/methodology/approach: A bibliometric assessment of 457 papers on the stock market from 2012 to 2022 was undertaken using Scopus. Bibliometrix's R-based online application Biblioshiny was used for this study. The program automatically identified notable publications, models, authors, countries, keywords, and article topics. We have also explored co-citations and thematic mapping in the same area.;  ; Findings: The result identifies the most effective models to measure the volatility in the stock market, the publications, authors, affiliations, and ruling nations in the same area. The statistics suggested an upward trend in publications from the period of 2012 to 2022. The result will be used for the investors who are interested to research in the same area.;  ; Research, Practical & Social implications: The researcher suggests a future research agenda and highlights the contributions which will help scholars, practitioners, and policymakers who want to work with stock market volatility.;  ; Originality/value: The findings show the significant researchers, co-authors, co-citations, and collaboration trends. This will show how stock market volatility specialists collaborate to find new patterns. Interconnected markets may cause volatility in many countries. Cross-country studies on how shocks influence other markets and how they rely on each other may dominate stock market volatility bibliometric study in the future.",11,2,e629,e629,Scopus; Originality; Volatility (finance); Stock market; Stock (firearms); Financial economics; Economics; Accounting; Political science; Sociology; Social science; Geography; Qualitative research; Context (archaeology); MEDLINE; Archaeology; Law,,,,,https://ojs.journalsdg.org/jlss/article/download/629/273 https://doi.org/10.55908/sdgs.v11i2.629,http://dx.doi.org/10.55908/sdgs.v11i2.629,,10.55908/sdgs.v11i2.629,,,0,000-108-134-192-285; 001-942-159-090-227; 003-105-265-428-679; 004-957-521-874-835; 005-777-499-401-289; 006-183-014-957-712; 006-877-420-535-175; 009-783-676-944-804; 015-688-844-090-142; 016-131-059-057-660; 022-729-764-306-486; 032-797-762-073-452; 033-264-994-716-95X; 033-455-912-481-192; 033-942-513-906-016; 036-580-129-411-83X; 036-817-568-956-578; 037-029-883-269-38X; 041-579-195-116-380; 047-439-620-332-361; 049-016-424-530-422; 058-088-466-346-016; 059-885-729-977-804; 061-380-874-424-374; 063-083-883-392-265; 063-108-435-529-481; 068-619-683-206-688; 073-742-208-177-19X; 080-683-153-707-574; 112-651-427-700-955; 113-471-530-783-611; 138-331-652-128-642; 140-644-510-314-262; 143-936-693-364-687; 156-364-484-521-720; 177-705-196-569-767,0,true,cc-by-nc,hybrid -065-599-239-553-750,Evaluating global research trends in special needs dentistry: A systematic bibliometrix analysis.,2024-06-16,2024,journal article,Clinical and experimental dental research,20574347,Wiley,United States,Nigashiny Senthilvadevel; Jimmy Ky; Matthew Ng; Tong Zhao; Massimo Aria; Luca D'Aniello; Mathew A W Lim; Federica Canfora; Giulio Fortuna; Michael McCullough; Tami Yap; Rita Paolini; Antonio Celentano,"Special needs dentistry (SND) is a vast and fragmented field of study. This comprehensive bibliometric analysis aimed to evaluate the scope of SND, including the existing knowledge base, distribution structure, quantitative relationships, and research trends.; A systematic search was conducted on March 10, 2022, using the Web of Science Core Collection database, covering the period from 1985 to 2021, focusing on studies reporting on special needs populations in a dentally relevant context. Records were title-screened and analyzed for key bibliometric indicators.; Among 48,374 articles, 13,869 underwent bibliometric analysis. Peak SND research occurred during 1985-1997. United States led in productivity, trailed by Brazil and Japan. University of Sao Paulo excelled in Brazil, University of Washington and University of North Carolina in the United States. The Journal of Dental Research was the most productive source of research and also had the highest number of citations, followed by Community Dentistry and Oral Epidemiology. Keyword analysis revealed that ""elderly"", ""caries"", and ""epidemiology"" were the most commonly used author keywords.; This study represents the first bibliometric analysis of SND literature. It emphasizes the need for increased collaboration between institutions and authors. Furthermore, it suggests focusing on research input from non-dental disciplines and populations with rarer intellectual or developmental conditions.; © 2024 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd.",10,3,e896,,Context (archaeology); Library science; Bibliometrics; Scope (computer science); Web of science; Medicine; Geography; Meta-analysis; Computer science; Pathology; Archaeology; Programming language,bibliometric; special needs dentistry; systematic,Bibliometrics; Humans; Dental Research/trends; Dental Care for Persons with Disabilities/statistics & numerical data,,,https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cre2.896 https://doi.org/10.1002/cre2.896,http://dx.doi.org/10.1002/cre2.896,38881256,10.1002/cre2.896,,PMC11180849,0,001-189-746-950-984; 007-372-929-585-776; 007-560-217-427-399; 013-507-404-965-47X; 014-207-925-436-866; 015-258-004-174-271; 021-270-925-433-767; 022-324-597-927-318; 034-600-684-728-898; 036-092-421-699-401; 038-427-749-271-489; 059-029-149-417-454; 059-090-549-637-934; 059-935-031-838-047; 065-599-239-553-750; 078-053-288-196-849; 082-211-532-654-553; 113-846-257-230-626; 126-012-767-927-205; 142-447-194-812-410,3,true,cc-by,gold -065-606-600-244-688,"R code used in Mazor & Doropoulos et al. (2018, Nature Ecology and Evolution)",2018-01-01,2018,dataset,Figshare,,,,Tessa Mazor; Christopher Doropoulos; Florian Schwarzmueller; Daniel W Gladish; Nagalingam Kumaran; Katharina Merkel; Moreno Di Marco; Vesna Gagic,"This script categorizes a database of article (48,234) downloaded from the Web of Science using the package bibliometrix into systems (Terrestrial, Marine, Freshwater), and into driver of biodiversity loss (Climate Change, Habitat Change, Invasive Species, Overexploitation and Pollution).",,,,,Ecology; Code (set theory); Geography; Biology; Computer science; Programming language; Set (abstract data type),,,,,https://figshare.com/articles/R_code_used_in_Mazor_Doropoulos_et_al_2018_Nature_Ecology_and_Evolution_/5662081,http://dx.doi.org/10.6084/m9.figshare.5662081,,10.6084/m9.figshare.5662081,,,0,,0,true,cc-by,gold -065-750-102-649-419,Marshall-Olkin distributions: a bibliometric study,2021-10-09,2021,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Isidro Jesús González-Hernández; Rafael Granillo-Macías; Carlos Rondero-Guerrero; I. Simón-Marmolejo,,126,11,9005,9029,Performance indicator; Probability distribution; Information retrieval; Bibliographic coupling; Bibliometric analysis; Visualization; Computer science; Sample (statistics); Scopus,,,,,https://EconPapers.repec.org/RePEc:spr:scient:v:126:y:2021:i:11:d:10.1007_s11192-021-04156-x https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics126.html#Gonzalez-Hernandez21 https://link.springer.com/article/10.1007/s11192-021-04156-x https://doi.org/10.1007/s11192-021-04156-x,http://dx.doi.org/10.1007/s11192-021-04156-x,,10.1007/s11192-021-04156-x,3207429154,,0,000-056-850-876-897; 000-753-206-347-218; 002-133-141-784-761; 002-520-198-824-007; 002-871-943-054-634; 004-124-074-705-039; 004-398-409-899-33X; 004-902-964-487-457; 005-838-987-956-220; 007-058-585-732-246; 007-656-463-269-193; 008-122-882-769-774; 008-372-410-469-943; 009-141-168-940-714; 010-756-533-279-896; 011-754-221-122-993; 013-307-534-075-276; 013-508-670-961-775; 014-330-287-147-974; 014-828-569-169-395; 014-932-288-976-633; 015-444-488-876-77X; 016-234-907-102-025; 016-415-997-628-161; 017-279-429-807-236; 017-466-029-166-031; 018-998-692-082-41X; 020-048-227-053-886; 021-023-632-316-200; 021-950-907-425-391; 022-482-840-610-446; 023-749-103-103-58X; 025-128-625-166-669; 025-596-028-729-280; 028-595-444-021-470; 029-327-547-791-289; 030-009-641-431-812; 032-374-291-500-870; 032-890-761-143-291; 033-058-272-606-612; 033-998-871-214-709; 035-790-725-794-960; 036-323-199-740-236; 036-382-052-467-298; 037-032-600-185-563; 037-226-128-058-32X; 037-247-195-122-240; 041-771-962-177-126; 042-091-768-272-856; 044-207-545-111-339; 045-050-845-291-726; 046-256-149-590-490; 046-331-642-714-060; 047-398-318-565-115; 048-126-004-147-276; 048-167-230-330-803; 049-024-102-064-49X; 049-443-877-309-41X; 051-364-373-461-115; 052-712-400-331-100; 053-837-544-466-595; 054-818-565-070-154; 055-987-181-980-582; 057-400-964-053-774; 058-810-704-504-848; 058-901-221-363-765; 058-963-538-387-355; 059-943-676-007-398; 060-625-285-345-658; 061-630-487-678-509; 062-633-580-582-94X; 063-105-594-471-252; 063-243-246-583-640; 064-894-491-027-619; 065-012-253-191-586; 065-923-786-455-705; 065-938-880-466-680; 066-872-232-190-062; 067-276-058-257-342; 067-323-843-843-776; 069-758-661-058-369; 070-052-174-830-826; 072-272-300-265-627; 073-937-136-938-673; 075-856-027-792-247; 077-604-861-732-547; 080-229-835-949-706; 080-305-832-551-745; 081-480-028-449-437; 081-615-339-335-627; 083-233-429-885-517; 083-385-713-969-622; 087-130-303-604-63X; 088-069-852-121-530; 088-337-844-008-536; 089-210-088-022-241; 089-371-767-451-547; 091-269-292-138-928; 091-891-796-993-725; 094-142-503-396-611; 094-282-262-221-611; 095-470-028-440-335; 097-234-720-663-402; 100-085-293-255-040; 100-438-016-653-543; 102-332-665-982-934; 102-581-551-347-85X; 104-053-001-107-900; 104-351-979-090-548; 106-057-055-796-554; 106-606-554-245-924; 111-741-050-675-317; 113-459-162-876-15X; 114-858-267-602-416; 118-055-178-324-81X; 119-976-547-444-810; 122-615-563-177-219; 122-994-276-731-988; 123-666-809-855-953; 126-199-369-415-282; 127-008-610-054-789; 132-769-356-012-096; 136-349-418-889-614; 137-360-609-114-663; 140-759-877-537-403; 141-551-555-946-830; 148-014-162-516-128; 148-906-507-426-405; 156-221-680-335-396; 158-345-528-783-394; 159-067-713-119-072; 159-174-483-451-742; 160-461-145-897-765; 164-817-776-528-675; 165-514-684-995-717; 165-781-791-376-053; 170-902-360-338-492; 171-385-821-058-658; 173-198-622-048-288; 175-791-452-618-531; 178-319-905-432-706; 183-426-868-412-996; 187-567-527-879-402; 189-108-067-614-621; 189-958-806-585-539; 190-018-155-830-427; 197-377-757-912-816,9,false,, -065-981-425-880-648,Asian soybean rust: a scientometric approach of Phakopsora pachyrhizi studies,2020-07-29,2020,journal article,Euphytica,00142336; 15735060,Springer Science and Business Media LLC,Netherlands,Daniela Meira; Leomar Guilherme Woyann; Antonio Henrique Bozi; Anderson Simionato Milioli; Eduardo Beche; Maiara Cecília Panho; Laura Alexandra Madella; Fabiana Barrionuevo; Volmir Sergio Marchioro; Giovani Benin,,216,8,1,12,Biotechnology; Phakopsora pachyrhizi; Asian soybean rust; Web of science; Food security; Biology,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,https://link.springer.com/article/10.1007/s10681-020-02667-x https://europepmc.org/article/AGR/IND607050747,http://dx.doi.org/10.1007/s10681-020-02667-x,,10.1007/s10681-020-02667-x,3045663853,,0,002-025-602-536-667; 002-052-422-936-00X; 009-572-931-019-115; 011-062-119-831-016; 013-507-404-965-47X; 017-091-412-253-295; 020-139-489-506-121; 025-683-531-406-986; 028-100-031-601-410; 028-815-306-228-627; 030-368-451-871-029; 034-896-455-300-375; 035-690-190-968-443; 035-821-108-017-866; 036-386-118-405-259; 040-707-363-460-955; 040-921-971-816-748; 042-131-996-791-870; 045-336-653-507-16X; 047-869-182-384-216; 049-703-930-698-388; 055-475-072-342-339; 056-426-226-149-95X; 060-321-325-803-295; 061-734-302-939-028; 074-790-077-150-714; 075-024-853-985-102; 075-188-224-612-283; 078-568-176-361-144; 085-486-294-046-73X; 087-097-950-816-100; 096-534-289-083-571; 101-752-490-869-458; 103-268-397-420-654; 106-147-141-268-802; 111-762-065-882-91X; 120-336-323-231-568; 120-645-599-941-471; 138-692-788-437-819; 139-010-307-455-844; 148-263-398-140-70X; 149-634-360-912-408; 150-325-162-873-23X; 150-344-927-102-124,17,false,, -065-990-500-899-395,Performance analysis and optimization in renewable energy systems: a bibliometric review,2025-02-25,2025,journal article,Discover Applied Sciences,30049261,Springer Science and Business Media LLC,,Kanak Saini; Monika Saini; Ashish Kumar; Dinesh Kumar Saini,"This study aims to conduct a bibliometric review of the performance analysis and optimization of renewable energy systems over the past 24 years. Using the Scopus database and the Biblioshiny (Bibliometrix R package), suitable keywords were combined for the articles published between 2000 and 2024, and 138 research papers were analyzed using the PRISMA framework. Of the selected articles, 72% focused on reliability and availability, and 58% focused on optimization techniques. On various aspects analysis was conducted such as annual scientific production, total citations per year, documents and authors citation, highlighted the relevant sources and authors, common key terms, etc. The growing focus on reliability and availability is highlighted in this analysis, indicating advancements in research and ever-more targeted research objectives. All these results help researchers in the future by giving them directions to explore more options to develop more efficient and reliable renewable energy solutions.",7,3,,,Renewable energy; Computer science; Engineering; Electrical engineering,,,,Manipal University Jaipur,,http://dx.doi.org/10.1007/s42452-025-06585-2,,10.1007/s42452-025-06585-2,,,0,000-319-989-480-004; 002-031-938-304-668; 003-476-137-698-765; 004-135-401-663-205; 004-311-207-334-328; 004-363-561-756-421; 007-506-018-469-177; 007-749-305-456-164; 009-891-154-712-57X; 011-462-044-082-809; 012-921-449-657-769; 016-332-109-935-347; 016-898-890-448-813; 018-608-943-231-074; 019-345-150-126-746; 019-776-039-909-640; 019-783-402-091-755; 020-743-073-343-518; 021-914-319-477-189; 022-211-454-698-748; 022-999-387-158-309; 024-357-021-680-045; 025-531-767-276-353; 026-491-668-605-863; 026-806-219-816-562; 026-895-087-780-955; 027-607-159-124-680; 027-940-587-566-345; 027-990-480-866-765; 028-212-018-141-372; 028-447-241-666-610; 029-812-231-742-746; 034-982-997-887-087; 035-524-522-699-179; 035-586-871-819-11X; 035-742-303-749-784; 038-309-949-432-219; 040-334-200-236-458; 040-517-112-260-185; 040-533-184-500-483; 041-401-522-441-618; 041-470-377-227-55X; 041-679-627-769-130; 042-246-238-282-014; 044-038-266-040-537; 044-425-900-493-42X; 044-428-314-092-686; 044-689-769-945-433; 044-860-200-229-704; 051-490-549-467-500; 052-164-488-874-120; 053-346-010-482-092; 053-948-893-429-460; 057-065-381-735-33X; 059-189-712-246-205; 059-569-968-785-039; 060-217-463-544-068; 060-859-065-822-522; 061-356-292-256-104; 061-935-639-019-623; 062-196-463-272-392; 062-671-832-500-11X; 063-508-901-033-671; 065-141-353-945-171; 065-658-335-723-008; 066-608-160-736-966; 066-740-046-355-746; 067-210-649-335-937; 067-741-893-980-885; 068-617-242-274-811; 069-274-596-984-700; 070-226-741-839-251; 070-646-256-536-768; 071-130-243-510-955; 072-510-080-115-344; 074-734-858-338-764; 075-068-583-679-678; 076-132-396-075-094; 076-461-445-645-186; 077-070-101-726-394; 077-552-240-658-696; 079-749-387-137-483; 080-742-695-082-684; 080-771-231-857-413; 081-486-749-957-957; 081-794-512-362-036; 082-042-189-476-520; 082-372-700-490-904; 083-258-472-194-616; 083-984-450-869-025; 084-319-178-290-335; 085-034-689-801-675; 086-944-076-394-594; 087-850-867-496-756; 090-922-487-033-029; 092-918-854-190-44X; 096-710-336-291-163; 096-875-303-634-305; 097-277-033-881-184; 098-953-751-149-710; 099-605-358-424-224; 100-616-720-138-448; 101-135-768-993-83X; 104-560-846-805-344; 105-650-462-947-955; 108-374-917-515-042; 108-711-087-040-467; 109-431-262-011-023; 111-002-773-481-736; 111-845-938-650-792; 116-481-251-472-86X; 119-193-954-389-467; 119-633-115-890-281; 120-152-324-575-163; 121-722-063-684-828; 122-307-211-910-742; 124-582-509-730-647; 127-276-665-277-614; 129-579-235-057-452; 130-459-584-832-356; 134-778-486-433-558; 134-788-333-832-864; 135-057-039-747-738; 135-370-452-259-94X; 135-988-135-167-966; 140-440-087-900-47X; 140-713-624-113-318; 146-349-725-530-815; 146-937-230-071-072; 147-483-204-407-786; 149-131-479-199-916; 149-184-726-504-228; 156-575-468-759-050; 156-663-452-148-554; 157-384-076-381-081; 161-957-484-847-434; 164-008-755-685-663; 164-242-472-467-979; 173-175-234-027-766; 178-567-741-778-913; 183-019-185-174-003; 183-848-354-405-334; 186-380-740-126-198; 191-161-513-167-898,1,true,"CC BY, CC BY-NC-ND",gold -066-457-055-013-154,Spatial social network research: a bibliometric analysis.,2022-07-09,2022,journal article,Computational urban science,27306852,Springer Science and Business Media LLC,Singapore,Ling Wu; Qiong Peng; Michael Lemke; Tao Hu; Xi Gong,"A restless and dynamic intellectual landscape has taken hold in the field of spatial social network studies, given the increasingly attention towards fine-scale human dynamics in this urbanizing and mobile world. The measuring parameters of such dramatic growth of the literature include scientific outputs, domain categories, major journals, countries, institutions, and frequently used keywords. The research in the field has been characterized by fast development of relevant scholarly articles and growing collaboration among and across institutions. The Journal of Economic Geography, Annals of the Association of American Geographers, and Urban Studies ranked first, second, and third, respectively, according to average citations. The United States, United Kingdom, and China were the countries that yielded the most published studies in the field. The number of international collaborative studies published in non-native English-speaking countries (such as France, Italy, and the Netherlands) were higher than native English-speaking countries. Wuhan University, the University of Oxford, and Harvard University were the universities that published the most in the field. ""Twitter"", ""big data"", ""networks"", ""spatial analysis"", and ""social capital"" have been the major keywords over the past 20 years. At the same time, the keywords such as ""social media"", ""Twitter"", ""big data"", ""geography"", ""China"", ""human mobility"", ""machine learning"", ""GIS"", ""location-based social networks"", ""clustering"", ""data mining"", and ""location-based services"" have attracted increasing attention in that same time frame, indicating the future research trends.",2,1,21,,Regional science; Field (mathematics); China; Geography; Annals; Social network analysis; Scale (ratio); Social media; Social capital; Economic geography; Social science; Sociology; Political science; Cartography; Mathematics; Archaeology; Pure mathematics; Law,Geography; Social media; Social network,,,Texas A&M Institute of Data Science Faculty Research Collaboration Program,https://link.springer.com/content/pdf/10.1007/s43762-022-00045-y.pdf https://doi.org/10.1007/s43762-022-00045-y,http://dx.doi.org/10.1007/s43762-022-00045-y,37096207,10.1007/s43762-022-00045-y,,PMC10115482,0,001-807-424-360-645; 002-052-422-936-00X; 006-192-702-630-670; 007-090-329-282-338; 009-232-132-724-44X; 010-242-782-778-938; 011-270-020-320-044; 011-854-399-312-637; 013-507-404-965-47X; 014-823-514-037-026; 016-026-570-945-417; 016-173-773-519-995; 016-358-380-085-98X; 016-666-177-414-527; 018-390-915-932-253; 018-590-476-891-096; 021-004-387-917-075; 021-496-870-557-974; 022-251-790-524-751; 025-576-072-224-249; 025-914-289-211-579; 027-991-394-082-053; 030-373-510-019-669; 030-829-065-088-334; 032-197-806-271-022; 034-409-929-986-938; 036-935-882-457-459; 039-472-655-920-627; 040-395-625-023-262; 046-992-864-415-70X; 047-457-988-197-427; 048-080-069-408-237; 053-266-816-267-287; 057-084-270-083-803; 057-490-845-206-856; 058-506-931-365-896; 066-810-047-386-49X; 067-550-041-232-068; 069-673-735-885-795; 071-939-600-808-335; 077-168-921-821-421; 081-405-580-444-744; 082-456-360-481-638; 083-569-564-056-200; 084-530-063-772-979; 084-638-260-152-466; 087-019-785-258-083; 089-073-066-008-897; 090-186-518-079-626; 091-008-418-033-625; 091-471-298-569-066; 092-896-258-953-696; 097-794-497-813-644; 099-254-214-697-766; 100-888-737-782-204; 104-259-948-699-236; 115-337-051-385-240; 120-885-678-404-810; 138-545-319-756-876; 142-034-227-995-028; 153-085-657-861-846; 180-988-579-345-075,7,true,cc-by,gold -066-610-216-711-286,"Análisis bibliométrico de la producción científica sobre alfabetización financiera en jóvenes, 2018-2023: una aplicación con el paquete de lenguaje R ""Bibliometrix""",2024-01-23,2024,journal article,Revista Ciencias de la Educación y el Deporte,30911648,Centro Internacional de Altos Estudios para la Promoción de la Educación e Innovación,,María Claudia Pacheco Barros; Yuraima Yuliza Hernández Meza; Jose Marcelo Torres Ortega,"El presente estudio analiza indicadores bibliométricos de la producción científica sobre alfabetización financiera en jóvenes a nivel global durante el periodo 2018-2023. Para ello, se empleó el lenguaje R y la aplicación Biblioshiny, perteneciente al paquete Bibliometrix, con el fin de generar métricas relacionadas con el producto. Los resultados evidencian que la mayor parte de la producción científica en esta temática se concentra en Estados Unidos y está indexada en Scopus. Además, la investigación estadounidense tiene presencia en todos los continentes, no solo a través de colaboraciones, sino también como líder en numerosos estudios. Asimismo, se observa una alta diversificación en la publicación de artículos en revistas de distintas disciplinas y una amplia variedad de enfoques, en el que la preeminencia de ciertos autores y temas clave sugiere que el campo ha pasado de un enfoque teórico a una aplicación más práctica, sugiriendo la necesidad de seguir promoviendo investigaciones que profundicen en la relación entre conocimiento financiero, comportamiento económico y bienestar individual, con el fin de diseñar políticas y estrategias que fomenten una mejor educación financiera a nivel global.",2,1,7,19,Humanities; Physics; Philosophy,,,,,,http://dx.doi.org/10.70262/rced.v2i1.2024.74,,10.70262/rced.v2i1.2024.74,,,0,000-467-742-936-748; 013-507-404-965-47X; 016-414-594-892-406; 041-754-951-597-411; 101-799-495-332-105; 112-199-486-287-592; 137-015-106-082-965,0,false,, -067-066-852-501-810,Global Research Trend Analysis of Osmanthus fragrans Based on Bibliometrix,2022-07-15,2022,journal article,Mobile Information Systems,1875905x; 1574017x,Wiley,Egypt,Tao Chen; Xusheng Gong,"Osmanthus fragrans is the ornamental and practical excellent garden tree featured with greening, beautification, and fragrance in one, and has been domesticated in China for 2500 years. Besides, an increasing number of papers on O. fragrans have been published so far, but these contributions have not been analyzed comprehensively. Considering that, in this research, a bibliometric methodology is adopted on documents related to O. fragrans obtained from the WoS database. The study demonstrated the main countries and institutions in terms of this field. Among them, the Chinese research on O. fragrans is in a leading position in the world. Regarding the specialization, the institution ranking is led by the Nanjing Forestry University, Henan University, and Zhejiang University. Apart from that, analysis on the keywords also highlighted the lines of research associated with plant functionality (e.g., antioxidant, antifungal activity, and anti-inflammatory activities), natural products (e.g., carotenoids, aroma, flavonoids, essential oils, phenylethanoid glycosides, and salidroside), and molecular biology (e.g., genetic diversity, transcription factors, and phylogeny). The results from this study also revealed that there is a lack of research on the production mechanism of floral fragrance and the flower color regulation mechanism in O. fragrans. Moreover, the aroma and flower color are gradually developing into the main areas of research on O. fragrans. It is also expected that future research in this field will focus on biochemistry and biomolecules.",2022,,1,10,Osmanthus fragrans; Nutmeg; Botany; Biology; Food science,,,,Hubei University of Science and Technology Research and Development Fund,https://downloads.hindawi.com/journals/misy/2022/4091962.pdf https://doi.org/10.1155/2022/4091962,http://dx.doi.org/10.1155/2022/4091962,,10.1155/2022/4091962,,,0,002-470-985-200-647; 002-608-692-783-235; 002-644-986-206-79X; 003-089-128-794-034; 003-298-982-034-65X; 005-434-625-023-73X; 008-334-442-476-569; 010-109-936-686-444; 012-402-412-372-511; 013-507-404-965-47X; 013-575-138-270-812; 014-139-263-171-78X; 019-337-231-551-437; 019-981-934-219-93X; 020-037-136-242-530; 022-402-138-363-235; 023-031-978-834-411; 024-187-944-876-370; 025-882-834-644-385; 026-547-863-609-448; 028-496-421-311-64X; 028-597-633-356-674; 029-108-270-478-491; 029-580-360-066-449; 031-882-759-664-34X; 032-141-248-341-870; 032-990-884-832-810; 033-099-638-527-179; 033-450-869-103-31X; 033-766-072-079-413; 034-496-866-461-701; 037-527-330-349-373; 042-404-214-471-452; 042-590-734-855-769; 045-059-619-135-646; 045-418-164-496-032; 046-288-152-140-681; 047-679-389-664-816; 048-310-634-806-352; 049-475-782-793-25X; 050-299-178-668-60X; 051-355-035-247-525; 053-253-344-707-316; 058-770-939-968-416; 063-297-110-862-863; 066-030-815-709-275; 067-717-569-622-808; 069-246-277-538-289; 074-865-421-277-495; 076-490-552-681-003; 083-423-847-622-928; 085-837-794-881-063; 086-426-790-454-128; 092-277-320-803-419; 097-826-360-523-869; 101-646-962-563-598; 115-349-335-360-57X; 120-809-097-337-600; 121-356-808-325-903; 121-949-786-439-902; 122-019-008-714-133; 124-224-902-234-068; 125-731-643-388-910; 130-241-749-977-86X; 135-854-842-598-630; 141-493-423-066-820; 145-548-893-625-552; 184-338-146-195-332,3,true,,gold -067-791-817-788-985,Operational efficiency and sustainability in smart ports: a comprehensive review,2024-06-27,2024,journal article,Marine Systems & Ocean Technology,1679396x; 21994749,Springer Science and Business Media LLC,,Paola Alzate; Gustavo A. Isaza; Eliana M. Toro; Jorge A. Jaramillo-Garzón; Sara Hernandez; Isabella Jurado; Diana Hernandez,"AbstractThe challenges of optimizing logistics operations in all links of the supply chain have led to the development of new dynamics around the revolution 4.0 and the response of operational efficiency linked to environmental sustainability. Smart ports are born as a strategy to meet customer needs from a technological evolution that generates quality logistical and operational responses. The objective of this review is to identify and to analyze the research perspectives related to smart ports. The implemented methodology considered a scientific mapping to determine the most relevant publications in terms of authors, journals, and countries with the greatest scientific participation in the subject and a network analysis based on the implementation of the tree metaphor of the graph theory. The R-studio software and the Bibliometrix plugin were used to process the information. The review considered 204 documents from the Scopus and Web of Science databases, identifying a growing trend in the number of enhanced publications as of 2019, with China being the country with the largest number of papers. In relation to research trends, the adaptation of ports to industry 4.0, maritime ports and technological security, and green and smart ports are the perspectives on the subject of study. Finally, an agenda for future research is presented.",19,1-2,120,131,Sustainability; Business; Environmental economics; Environmental resource management; Computer science; Environmental science; Economics; Ecology; Biology,,,,University of Caldas,,http://dx.doi.org/10.1007/s40868-024-00142-z,,10.1007/s40868-024-00142-z,,,0,002-479-330-645-945; 003-316-159-327-276; 009-819-989-474-753; 011-249-559-234-645; 011-889-050-913-341; 014-845-584-878-653; 015-037-146-831-83X; 016-106-645-521-599; 016-645-295-742-764; 016-915-134-401-86X; 017-750-600-412-958; 018-865-994-762-155; 023-748-509-769-088; 026-591-134-281-735; 026-751-007-974-782; 030-411-655-780-963; 032-634-191-515-600; 039-908-481-893-335; 043-993-580-694-60X; 045-731-189-824-128; 047-291-734-468-955; 048-563-782-559-977; 051-984-367-923-288; 053-471-185-015-296; 053-598-695-896-482; 055-301-786-169-38X; 055-636-295-859-778; 056-558-302-986-990; 057-076-470-697-594; 057-803-697-074-453; 060-798-107-606-54X; 068-256-263-080-118; 069-046-938-842-901; 071-527-787-883-851; 076-945-303-354-288; 077-446-102-740-449; 084-327-248-819-223; 091-440-868-760-873; 092-416-936-225-669; 093-609-577-836-587; 096-287-550-959-958; 097-548-296-670-890; 102-936-722-681-976; 106-159-908-223-537; 106-189-209-559-469; 106-680-051-937-393; 106-945-295-200-575; 108-201-041-749-702; 112-528-049-287-986; 116-623-370-984-594; 119-557-426-467-219; 131-051-570-289-695; 138-930-645-676-610; 139-352-952-634-490; 151-082-890-683-306; 151-336-483-768-908; 157-015-485-754-631; 162-738-729-683-623; 163-788-050-406-103; 178-173-301-700-598; 185-082-076-048-15X; 186-226-233-184-46X,5,true,cc-by,hybrid -067-837-394-250-040,"Mapping the Knowledge Structure of Image Recognition in Cultural Heritage: A Scientometric Analysis Using CiteSpace, VOSviewer, and Bibliometrix.",2024-10-26,2024,journal article,Journal of imaging,2313433x,MDPI AG,Switzerland,Fei Ju,"The application of image recognition techniques in the realm of cultural heritage represents a significant advancement in preservation and analysis. However, existing scholarship on this topic has largely concentrated on specific methodologies and narrow categories, leaving a notable gap in broader understanding. This study aims to address this deficiency through a thorough bibliometric analysis of the Web of Science (WoS) literature from 1995 to 2024, integrating both qualitative and quantitative approaches to elucidate the macro-level evolution of the field. Our analysis reveals that the integration of artificial intelligence, particularly deep learning, has significantly enhanced digital documentation, artifact identification, and overall cultural heritage management. Looking forward, it is imperative that research endeavors expand the application of these techniques into multidisciplinary domains, including ecological monitoring and social policy. Additionally, this paper examines non-invasive identification methods for material classification and damage detection, highlighting the role of advanced modeling in optimizing the management of heritage sites. The emergence of keywords such as 'ecosystem services', 'models', and 'energy' in the recent literature underscores a shift toward sustainable practices in cultural heritage conservation. This trend reflects a growing recognition of the interconnectedness between heritage preservation and environmental sciences. The heightened awareness of environmental crises has, in turn, spurred the development of image recognition technologies tailored for cultural heritage applications. Prospective research in this field is anticipated to witness rapid advancements, particularly in real-time monitoring and community engagement, leading to the creation of more holistic tools for heritage conservation.",10,11,272,272,Computer science; Cultural heritage; Data science; Artificial intelligence; Pattern recognition (psychology); Geography; Archaeology,artificial intelligence; cultural heritage; deep learning; image recognition,,,,,http://dx.doi.org/10.3390/jimaging10110272,39590736,10.3390/jimaging10110272,,PMC11596010,0,002-052-422-936-00X; 002-292-797-382-632; 002-849-903-329-92X; 004-474-475-701-67X; 005-982-561-440-354; 006-881-405-466-302; 007-008-329-893-707; 007-016-826-558-870; 007-790-811-502-826; 008-440-910-997-170; 009-288-561-225-748; 010-156-774-588-498; 010-710-930-680-815; 012-201-674-350-055; 012-490-633-198-046; 013-507-404-965-47X; 014-129-204-531-23X; 014-664-634-920-141; 015-084-189-459-486; 018-699-679-009-082; 018-720-205-748-506; 020-233-013-143-936; 020-258-517-776-818; 021-061-873-198-425; 021-166-644-524-339; 021-623-653-728-019; 022-029-163-714-436; 023-119-241-222-169; 025-560-260-031-19X; 026-162-818-476-378; 027-116-670-575-757; 027-353-704-692-118; 027-359-282-287-055; 027-699-663-637-910; 031-631-312-932-831; 032-917-845-651-629; 033-039-362-104-022; 033-127-677-566-360; 033-280-696-357-872; 033-723-069-285-048; 034-768-039-318-254; 035-871-769-885-244; 035-980-236-978-950; 036-345-838-519-210; 037-036-602-845-527; 039-629-054-881-020; 040-427-246-261-483; 040-839-309-379-317; 041-608-489-756-041; 041-957-992-872-184; 042-568-239-705-957; 043-353-969-833-510; 044-070-391-700-506; 044-147-544-148-875; 045-066-545-193-207; 045-178-135-208-548; 046-297-904-256-543; 046-992-864-415-70X; 049-565-209-230-939; 050-609-067-982-963; 051-064-261-835-026; 051-142-039-623-015; 055-136-948-436-254; 055-276-119-465-159; 058-489-285-981-130; 060-055-658-043-459; 064-538-809-469-708; 065-026-194-566-751; 065-480-816-099-749; 065-550-135-106-799; 066-660-231-137-417; 066-853-704-371-90X; 067-169-321-672-866; 067-738-157-102-454; 067-885-654-222-537; 068-743-667-184-763; 069-213-457-425-504; 069-459-013-403-937; 071-878-836-294-733; 072-831-421-252-839; 074-204-429-624-940; 075-426-128-555-275; 076-777-044-602-899; 077-325-214-996-165; 081-914-777-449-704; 085-399-897-737-577; 086-136-296-391-576; 086-299-888-724-844; 087-272-341-021-148; 088-472-417-031-864; 088-940-142-655-84X; 089-419-977-724-769; 091-797-143-624-200; 091-891-734-697-576; 092-825-018-575-990; 093-086-223-108-451; 093-167-398-633-770; 093-328-482-392-062; 093-697-118-211-927; 094-659-365-968-635; 094-934-769-585-837; 095-492-246-831-956; 100-808-623-252-43X; 100-983-695-282-089; 102-255-515-930-446; 104-385-879-472-982; 107-601-960-327-259; 107-735-388-187-921; 110-115-620-035-238; 110-570-709-807-964; 114-935-059-121-796; 116-814-305-941-872; 118-053-308-843-433; 118-830-719-338-654; 118-868-718-416-124; 120-342-516-491-818; 124-328-723-157-550; 125-943-204-417-892; 127-688-638-042-052; 129-142-876-608-849; 132-890-258-159-427; 134-783-725-757-987; 138-991-403-049-285; 139-875-645-558-718; 141-033-730-798-071; 142-670-624-324-17X; 143-129-484-528-242; 143-404-158-563-505; 145-105-885-013-182; 146-631-388-152-444; 152-299-195-234-748; 154-727-713-659-895; 156-987-841-554-573; 158-537-545-166-343; 160-473-128-721-432; 160-573-104-079-922; 161-022-758-518-942; 163-097-824-841-174; 164-299-560-639-424; 166-139-790-924-394; 167-820-354-860-148; 169-634-104-656-762; 174-475-974-890-443; 177-037-466-995-31X; 177-506-185-605-118; 179-131-963-023-62X; 180-001-488-921-315; 181-239-130-796-368; 181-797-068-816-79X; 186-231-039-851-835; 198-415-036-911-355; 199-810-681-206-989,5,true,cc-by,gold -068-170-282-076-539,"Digital Transition, Innovation and Business Models in Airbnb: A Bibliometric Analysis",2024-06-25,2024,book chapter,Springer Proceedings in Business and Economics,21987246; 21987254,Springer Nature Switzerland,,Ana María Barrera-Martínez; Eduardo Parra-López,"AbstractThe process of digital transition often involves disruptive innovations in the ways we work, processes and how we understand firms. These flexible processes and their ability to be innovative require mechanisms of collective knowledge and uniqueness. Similarly, the application of business models and the management of Airbnb is another field of study, which has not been explored in sufficient depth in the academic literature. However, the applications and possible derivatives of their impact need to be clarified. To this end, a bibliometric analysis is carried out through the VOSviewer and Bibliometrix software’s, grouping the aforementioned constructs and resulting in a total analysis of 4729 published works, 97 countries and 2872 authors. After this process, the reality that links the phenomena of digital transition, innovation, business models and Airbnb will be known and future lines of research are proposed to complete this conclusion.",,,195,204,Transition (genetics); Business; Business model; Economic geography; Data science; Computer science; Marketing; Geography; Biochemistry; Chemistry; Gene,,,,,,http://dx.doi.org/10.1007/978-3-031-52607-7_18,,10.1007/978-3-031-52607-7_18,,,0,004-987-437-751-610; 010-168-316-482-221; 042-066-545-146-356; 046-992-864-415-70X; 049-391-379-302-694; 054-960-204-932-617; 089-832-166-087-566; 096-061-214-240-715; 107-518-655-388-824; 134-461-231-093-98X; 195-638-802-395-994,0,true,cc-by,hybrid -068-293-194-798-187,Fiqh on Finance: A Scientometric Analysis using Bibliometrix,2021-05-18,2021,,,,,,Aam Slamet Rusydiana; Aisyah Assalafiyah; Yulizar D. Sanrego; Lina Marlina,,,,,,Positive economics; Business; Fiqh,,,,,https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=10068&context=libphilprac https://digitalcommons.unl.edu/libphilprac/5436/,https://digitalcommons.unl.edu/libphilprac/5436/,,,3169252001,,0,000-536-793-330-945; 024-821-782-412-930; 054-992-114-644-642; 061-657-402-947-723; 080-984-383-040-989; 112-453-292-967-435; 164-440-012-349-880; 172-016-003-187-100,0,false,, -068-371-633-724-376,A bibliometric review of vegetation response to climate change,2021-10-25,2021,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Gbenga Abayomi Afuye; Ahmed Mukalazi Kalumba; Emmanuel Tolulope Busayo; Israel R. Orimoloye,,29,13,1,13,Climate change; Dominance (economics); Regional science; Field (geography); Vegetation; Bibliometrics; Geography; Citation; Annual growth rate; Forest ecology,Bibliometrics; Climate change; Precipitation; Temperature; Vegetation,"Bibliometrics; China; Climate Change; Databases, Factual; Ecosystem",,"Govan Mbeki Research and Development Centrem, University of Fort Hare",https://www.ncbi.nlm.nih.gov/pubmed/34697705 https://link.springer.com/article/10.1007/s11356-021-16319-7,http://dx.doi.org/10.1007/s11356-021-16319-7,34697705,10.1007/s11356-021-16319-7,3210602307,,0,000-454-715-402-609; 001-719-026-803-199; 002-389-282-815-604; 004-092-436-774-549; 004-988-566-253-022; 011-179-702-193-751; 013-507-404-965-47X; 013-524-854-219-241; 015-215-890-668-945; 015-233-121-128-177; 017-259-617-884-986; 017-884-145-542-171; 019-134-892-684-990; 019-696-069-676-331; 019-793-160-855-722; 022-311-047-689-850; 025-976-701-448-679; 028-070-678-720-010; 028-173-695-450-579; 029-220-433-869-084; 029-323-562-446-290; 030-882-691-093-109; 032-419-149-514-282; 033-287-473-265-147; 034-768-039-318-254; 035-330-847-069-591; 036-340-921-232-744; 042-118-564-472-423; 042-659-323-146-573; 043-968-898-129-569; 044-473-620-435-483; 046-894-003-026-199; 047-510-880-543-009; 047-915-240-613-449; 047-936-806-299-122; 049-562-251-831-208; 053-335-540-527-012; 055-517-473-529-826; 057-803-697-074-453; 060-551-000-401-873; 065-108-368-829-080; 069-997-717-401-217; 070-559-334-614-069; 073-008-010-322-076; 077-661-090-516-942; 078-136-827-106-560; 080-111-916-272-449; 089-829-921-690-039; 107-792-443-930-898; 115-246-391-402-795; 116-970-974-511-575; 120-215-318-300-863; 122-415-544-444-960; 126-829-994-137-752; 128-217-524-056-953; 130-363-100-878-408; 137-806-786-177-589; 140-857-528-803-40X; 142-509-183-021-323; 149-037-342-008-401; 149-287-694-931-947; 154-961-708-843-976; 160-328-729-324-669; 198-335-203-199-642,46,false,, -068-503-926-706-86X,Quo vadis Radiomics? Bibliometric analysis of 10-year Radiomics journey.,2023-04-18,2023,journal article,European radiology,14321084; 09387994,Springer Science and Business Media LLC,Germany,Stefania Volpe; Federico Mastroleo; Marco Krengli; Barbara Alicja Jereczek-Fossa,"Radiomics is the high-throughput extraction of mineable and-possibly-reproducible quantitative imaging features from medical imaging. The aim of this work is to perform an unbiased bibliometric analysis on Radiomics 10 years after the first work became available, to highlight its status, pitfalls, and growing interest.; Scopus database was used to investigate all the available English manuscripts about Radiomics. R Bibliometrix package was used for data analysis: a cumulative analysis of document categories, authors affiliations, country scientific collaborations, institution collaboration networks, keyword analysis, comprehensive of co-occurrence network, thematic map analysis, and 2021 sub-analysis of trend topics was performed.; A total of 5623 articles and 16,833 authors from 908 different sources have been identified. The first available document was published in March 2012, while the most recent included was released on the 31st of December 2021. China and USA were the most productive countries. Co-occurrence network analysis identified five words clusters based on top 50 authors' keywords: Radiomics, computed tomography, radiogenomics, deep learning, tomography. Trend topics analysis for 2021 showed an increased interest in artificial intelligence (n = 286), nomogram (n = 166), hepatocellular carcinoma (n = 125), COVID-19 (n = 63), and X-ray computed (n = 60).; Our work demonstrates the importance of bibliometrics in aggregating information that otherwise would not be available in a granular analysis, detecting unknown patterns in Radiomics publications, while highlighting potential developments to ensure knowledge dissemination in the field and its future real-life applications in the clinical practice.; This work aims to shed light on the state of the art in radiomics, which offers numerous tangible and intangible benefits, and to encourage its integration in the contemporary clinical practice for more precise imaging analysis.; • ML-based bibliometric analysis is fundamental to detect unknown pattern of data in Radiomics publications. • A raising interest in the field, the most relevant collaborations, keywords co-occurrence network, and trending topics have been investigated. • Some pitfalls still exist, including the scarce standardization and the relative lack of homogeneity across studies.; © 2023. The Author(s).",33,10,6736,6745,Radiomics; Bibliometrics; Radiogenomics; Medicine; Data science; Medical physics; Computer science; Library science; Radiology,Bibliometrics; Diagnostic imaging; Machine learning,"Humans; Artificial Intelligence; COVID-19; Tomography, X-Ray Computed; Bibliometrics; Liver Neoplasms",,Università degli Studi del Piemonte Orientale Amedeo Avogrado,https://link.springer.com/content/pdf/10.1007/s00330-023-09645-6.pdf https://doi.org/10.1007/s00330-023-09645-6,http://dx.doi.org/10.1007/s00330-023-09645-6,37071161,10.1007/s00330-023-09645-6,,PMC10110486,0,007-391-648-979-481; 013-507-404-965-47X; 013-683-191-846-68X; 016-346-732-996-341; 016-408-402-296-570; 021-936-746-204-879; 022-611-590-812-00X; 027-525-069-453-916; 038-317-554-529-534; 038-875-171-796-578; 045-510-232-446-005; 045-806-026-232-420; 046-992-864-415-70X; 051-739-270-416-512; 053-655-655-560-528; 061-708-131-411-544; 064-400-499-357-900; 070-791-835-923-368; 092-429-030-442-934; 092-563-420-456-132; 102-193-379-614-260; 130-909-651-506-602; 145-259-424-126-514,21,true,cc-by,hybrid -068-714-496-413-820,A bibliometric analysis for Indian summer monsoon variability,2024-05-25,2024,journal article,Spatial Information Research,23663286; 23663294,Springer Science and Business Media LLC,,Netrananda Sahu; Pritiranjan Das; Satyaban B. Ratna; Atul Saini; Suraj Kumar Mallick; Anil Kumar; Mrutyunjay Mohapatra,,32,5,623,639,Monsoon; Geography; Climatology; Physical geography; Geology; Meteorology,,,,,,http://dx.doi.org/10.1007/s41324-024-00587-9,,10.1007/s41324-024-00587-9,,,0,002-557-838-630-083; 007-916-613-602-608; 009-286-240-384-618; 009-414-992-295-283; 012-418-987-737-557; 012-883-002-514-679; 013-507-404-965-47X; 013-524-854-219-241; 016-831-502-089-673; 020-469-200-370-270; 020-549-376-119-821; 023-046-522-938-900; 023-374-329-058-664; 024-993-504-891-928; 026-618-700-398-039; 027-168-917-889-614; 030-514-165-865-560; 030-825-258-828-011; 031-410-017-386-103; 034-339-495-303-632; 036-868-701-509-575; 040-040-670-652-305; 040-969-805-240-336; 044-617-588-391-707; 046-430-710-219-04X; 046-613-125-491-773; 046-857-602-512-129; 053-059-570-395-382; 054-827-360-677-491; 057-412-163-928-911; 058-098-847-554-547; 059-073-424-480-617; 059-267-403-189-762; 060-602-937-952-065; 063-337-545-786-39X; 063-529-355-260-430; 064-794-664-567-907; 065-365-565-341-241; 066-041-473-795-647; 068-600-218-121-961; 069-215-854-524-839; 070-423-026-723-543; 071-130-848-654-628; 071-533-833-974-887; 074-388-719-149-26X; 075-549-918-993-771; 075-665-855-132-090; 076-490-350-495-982; 079-188-033-777-427; 082-890-007-930-836; 084-698-477-234-133; 101-269-773-455-167; 109-927-734-487-484; 110-932-534-554-824; 111-089-945-904-825; 112-671-989-326-49X; 113-008-791-342-369; 118-687-485-206-085; 118-889-247-222-747; 120-873-200-476-286; 131-020-864-461-938; 135-060-100-000-615; 136-722-138-288-884; 139-963-112-131-762; 145-141-468-775-870; 149-711-701-803-514; 157-349-669-448-006; 157-484-280-534-485; 175-591-483-656-470; 182-539-542-321-407; 188-256-684-147-174,1,false,, -068-880-978-731-171,Innovation in creative industries: Bibliometrix analysis and research agenda,2024-03-08,2024,journal article,Journal of Economic Analysis,28110943,Anser Press Pte. Ltd.,,Paulin Gohoungodji,"<p style=""text-align: justify;""><span lang=""EN-US"" style=""font-size: 14pt; font-family: 'times new roman', times, serif;"">Innovation has received a great attention in the creative industries literature. We propose in this study a bibliometric method to examine the literature on innovation in creative industries (ICI). A file of 656 manuscripts published on ICI between 1998 and 2022 was retrieved from the Web of Science Core Collection for analysis. The results highlight the evolution of study volume, authors, affiliated institutions and countries, author networks, keyword co-occurrences, and keyword networks. The study also includes a thematic map that highlights four types of research: driving themes (e.g., digital technology, cultural innovation, performing arts, product innovation, innovation management); core and cross-cutting themes (e.g., creativity, digitization, technology, copyright); emerging themes (e.g., gender, artificial intelligence, sustainability); and specialized and peripheral themes (e.g., gender, blockchain, digital music). We finally conclude by proposing future perspectives and a research agenda in this area.</span></p>",,,,,Digitization; Creative industries; Creativity; Style (visual arts); The arts; Product (mathematics); Innovation management; Thematic analysis; Sociology; Library science; Political science; Business; Marketing; Social science; Computer science; Qualitative research; Telecommunications; Art; Visual arts; Law; Geometry; Mathematics,,,,,https://anserpress.org/article/312/pdf?journal_slug=jea https://doi.org/10.58567/jea04010002,http://dx.doi.org/10.58567/jea04010002,,10.58567/jea04010002,,,0,002-870-393-077-06X; 004-313-882-888-024; 006-235-651-110-540; 009-276-782-493-545; 011-783-697-629-426; 013-524-854-219-241; 014-088-733-758-490; 015-552-759-860-955; 018-903-885-947-93X; 020-187-154-682-285; 022-249-054-036-001; 022-858-301-439-259; 023-218-841-447-867; 024-214-661-738-673; 025-497-554-725-120; 031-266-074-083-914; 042-101-229-037-845; 042-453-581-338-62X; 046-365-249-259-271; 048-263-421-514-867; 054-130-177-434-416; 057-402-954-402-01X; 058-985-903-816-689; 059-833-627-016-40X; 063-668-617-269-858; 066-107-925-100-05X; 072-919-435-610-672; 073-623-032-679-230; 079-224-211-261-69X; 088-410-864-054-984; 091-459-782-527-093; 091-520-384-456-824; 092-353-895-976-662; 096-401-855-806-668; 099-466-215-609-11X; 101-816-166-264-684; 107-304-297-992-963; 119-275-209-604-47X; 122-069-673-462-904; 124-200-526-353-71X; 128-207-424-254-865; 135-092-089-204-217; 137-428-814-203-989; 140-505-486-168-815; 152-932-300-734-332; 153-420-616-102-072; 154-387-088-722-458; 159-672-445-256-008; 161-089-512-430-031; 168-104-447-364-222; 181-649-731-143-76X; 187-387-518-917-472,0,true,cc-by,hybrid -069-244-563-710-511,"Bibliometric Analysis of Environmental, Social, and Governance Management Research from 2002 to 2021",2022-12-02,2022,journal article,Sustainability,20711050,MDPI AG,Switzerland,Hung-Jung Siao; Sue-Huai Gau; Jen-Hwa Kuo; Ming-Guo Li; Chang-Jung Sun,"Extreme weather events caused by climate change have increased people’s focus on sustainability. Environmental, social, and governance management (ESGM) has become crucial for corporate operations and development; ESGM has attracted the attention of the academic communities, and the number of related studies has continued to increase. However, this topic is multidisciplinary and diverse; therefore, this study used the Web of Science Core Collection Database to conduct a bibliometric analysis of ESGM-related articles published from 2002 to 2021. Bibliometrix (R language), VOSviewer, and CiteSpace were used to identify and analyze research trends related to the number of studies, research fields, authors, national institutions, and keywords. The importance of management and governance was identified through keyword analysis; important keywords identified were financial performance, adaptive governance, property rights, sustainable development goals, and corporate governance.",14,23,16121,16121,Corporate governance; Multidisciplinary approach; Sustainability; Bibliometrics; Web of science; Sustainable development; Political science; Business; Sustainability science; Corporate social responsibility; Environmental governance; Environmental resource management; Knowledge management; Accounting; Public relations; Social sustainability; Economics; Computer science; Library science; Ecology; Finance; MEDLINE; Law; Biology,,,,Ministry of Education,https://www.mdpi.com/2071-1050/14/23/16121/pdf?version=1669980113 https://doi.org/10.3390/su142316121,http://dx.doi.org/10.3390/su142316121,,10.3390/su142316121,,,0,000-570-749-630-368; 001-153-564-508-98X; 002-052-422-936-00X; 002-832-232-633-697; 005-657-459-454-849; 006-586-053-043-792; 010-065-762-504-134; 010-209-380-729-338; 010-493-806-178-301; 011-294-360-691-323; 011-485-089-313-385; 011-520-157-595-101; 013-173-294-160-664; 013-209-248-887-119; 014-145-677-806-491; 014-736-310-133-635; 014-903-724-136-284; 015-061-557-351-590; 016-142-460-874-417; 016-397-705-925-724; 018-114-653-012-578; 020-073-106-062-625; 020-933-107-828-263; 021-676-651-710-439; 022-358-954-631-781; 024-826-273-997-937; 024-837-569-554-936; 025-398-038-708-910; 027-081-112-766-738; 027-208-805-619-111; 028-013-939-391-155; 028-272-360-627-444; 029-827-565-817-826; 031-570-688-927-890; 031-887-824-042-882; 031-902-648-193-245; 033-327-370-398-143; 034-768-039-318-254; 035-730-905-989-808; 036-920-196-808-43X; 040-463-855-828-789; 041-199-316-879-567; 042-661-607-449-747; 043-570-193-270-001; 044-284-651-137-662; 045-421-755-421-785; 045-588-405-084-859; 047-295-888-153-276; 050-252-270-491-60X; 050-523-809-280-040; 050-990-245-194-851; 052-364-237-739-043; 055-659-301-934-626; 056-002-925-128-630; 061-204-771-484-494; 061-962-132-890-210; 063-237-012-763-146; 063-534-847-919-947; 070-270-836-471-734; 077-130-511-788-880; 078-692-029-386-833; 081-248-115-290-35X; 082-372-272-204-560; 086-325-225-996-300; 091-392-656-416-030; 091-597-870-988-047; 092-250-164-504-15X; 102-927-231-022-138; 103-886-345-687-726; 107-077-724-627-42X; 111-113-605-670-353; 114-933-813-221-985; 122-658-801-737-120; 124-935-879-228-76X; 132-943-910-518-74X; 136-079-131-661-463; 136-502-700-527-607; 137-512-611-735-661; 141-289-222-959-472; 143-998-738-124-85X; 159-382-288-612-420; 179-606-970-615-670,14,true,,gold -069-299-093-299-34X,Bibliometric analysis: Spatial skills and gender in education,2024-04-30,2024,journal article,Desimal: Jurnal Matematika,26139081; 26139073,Raden Intan State Islamic University of Lampung,,Aji Raditya; Muhamad Syazali,"Spatial skills, the ability to perceive, understand, and manipulate shapes and spatial relationships, are fundamental to human cognition and have a significant impact on success in STEM (Science, Technology, Engineering, and Mathematics) career. The purpose of this study is to analyze the scientific research related to spatial skills and gender in education on Scopus database. This research also reveals the current research trends and research gaps on this subject. Bibliometric analysis is used to answer those objectives, with platforms such as R packages (Bibliometrix) and Vos Viewer software to help the analysis. This study addresses four research issues as follows: (i) the landscape of research on spatial skills and gender; (ii) the leading countries and institutions on spatial skills and gender research; (iii) the most cited journal; and (iv) the most cited authors; (v) the most cited articles; (vi) the most popular and least popular keywords.",7,1,137,137,Psychology; Mathematics education; Geography,,,,,,http://dx.doi.org/10.24042/djm.v7i1.23211,,10.24042/djm.v7i1.23211,,,0,,0,true,cc-by-sa,gold -070-005-574-857-938,Artificial Intelligence in Quality Assurance: A New Paradigm for Total Quality Management,2025-05-23,2025,journal article,Operations Research Forum,26622556,Springer Science and Business Media LLC,,Jothikumar R; Mohan Raju S; Mohan Y.C; Susi S; Jayendra Kumar,,6,2,,,Quality assurance; Total quality management; Quality (philosophy); Quality audit; Process management; Business; Computer science; Engineering management; Engineering; Operations management; Accounting; Audit; Philosophy; External quality assessment; Epistemology; Lean manufacturing,,,,,,http://dx.doi.org/10.1007/s43069-025-00476-3,,10.1007/s43069-025-00476-3,,,0,002-052-422-936-00X; 002-076-628-649-651; 002-081-236-895-702; 008-872-461-604-616; 017-750-600-412-958; 030-092-122-469-683; 033-182-607-989-810; 034-412-500-817-573; 040-854-172-897-919; 041-455-789-351-412; 044-363-543-343-309; 045-422-273-148-899; 046-992-864-415-70X; 047-134-478-431-993; 050-003-265-374-700; 051-947-693-585-226; 085-161-588-118-529; 095-394-786-299-690; 097-298-340-099-224; 098-536-388-649-376; 122-045-414-003-002; 155-142-655-983-795; 157-705-821-404-883; 184-100-477-447-725,0,false,, -070-016-727-688-519,A systematic mapping review of foreign direct investment by multinational corporations in emerging economies,2025-02-27,2025,journal article,Humanities and Social Sciences Communications,26629992,Springer Science and Business Media LLC,,Ahmed Nazzal; Angels Monserrat Niñerola; Maria-Victoria Sánchez-Rebull; Maria Glòria Barberà-Mariné,"This study aims to provide new insights into the evolution and current state of the literature on foreign direct investment (FDI) and multinational corporations (MNCs) over the past five decades, with a particular focus on emerging economies. Using a bibliometric methodology, the study analyzes 1386 articles authored by 2335 researchers and published in 461 journals between 1987 and 2023. The results show that the literature on FDI by MNCs in emerging economies can be broken down into subthemes such as FDI impacts on economic development, the internationalization of emerging economy multinationals, the effects of institutional factors on MNC behavior and performance and the need to rethink existing international business theories to explain how emerging economy multinationals have changed over time. Additionally, the citation analysis confirmed the observations derived from literature trends and thematic mapping analyses. The results also reveal a significant increase in publications since 2010. Eighty-five percent of the articles were published in the last ten years, yet those articles received a sufficient number of citations for inclusion in the network (56.8%). This study contributes to the international literature by expanding on previous reviews of the topic and providing intriguing insights and recommendations for future research. The current article provides several starting points for practitioners and researchers investigating FDI. It contributes to broadening the scope of the field and suggesting avenues for future studies.",12,1,,,Multinational corporation; Foreign direct investment; Emerging markets; Business; Economic geography; International trade; Economics; Finance; Macroeconomics,,,,,,http://dx.doi.org/10.1057/s41599-025-04571-y,,10.1057/s41599-025-04571-y,,,0,000-071-607-559-555; 000-579-432-354-052; 000-765-190-097-434; 001-187-191-963-888; 001-804-505-713-904; 002-052-422-936-00X; 002-943-615-906-965; 003-850-036-658-008; 003-976-701-551-264; 004-560-629-791-024; 005-950-727-317-481; 006-576-266-922-281; 007-423-226-733-557; 009-396-295-219-887; 009-695-690-664-825; 010-083-219-835-969; 010-145-649-971-46X; 010-163-096-509-986; 010-588-059-728-788; 011-219-659-274-102; 012-125-430-877-959; 012-624-352-617-049; 013-412-461-801-998; 013-507-404-965-47X; 013-524-854-219-241; 014-081-280-179-32X; 014-408-240-739-064; 015-692-170-714-052; 016-768-073-428-26X; 017-750-600-412-958; 017-757-190-228-163; 017-952-351-909-220; 021-944-720-672-500; 022-749-267-318-425; 022-831-103-846-54X; 023-794-302-579-954; 024-384-932-285-947; 025-033-336-373-256; 025-422-594-283-615; 025-614-923-103-838; 026-169-050-342-031; 026-906-895-019-276; 027-690-220-065-414; 027-789-563-319-957; 027-971-145-143-443; 028-666-494-809-771; 029-303-270-603-68X; 032-814-495-884-104; 035-009-601-258-105; 035-358-700-523-010; 035-910-741-165-578; 037-178-484-587-646; 037-815-640-424-494; 040-402-313-955-469; 040-830-364-062-573; 042-213-444-543-747; 042-272-316-156-187; 042-872-320-263-080; 045-422-273-148-899; 045-538-349-555-146; 046-846-423-138-529; 047-554-788-068-027; 047-567-038-697-679; 048-350-249-309-25X; 049-141-864-468-602; 049-391-379-302-694; 049-410-524-682-20X; 050-442-996-416-614; 052-040-185-996-003; 053-930-225-429-515; 054-844-955-114-326; 056-026-271-175-783; 056-581-943-582-561; 056-809-515-326-80X; 059-841-006-925-387; 060-110-039-971-60X; 060-204-351-064-104; 061-141-394-037-983; 061-545-915-576-458; 064-158-745-887-681; 067-737-141-077-368; 069-412-604-372-388; 071-280-786-177-056; 071-766-826-866-56X; 073-775-823-470-313; 075-004-097-669-017; 075-804-393-713-532; 078-450-469-428-687; 079-278-714-415-834; 081-468-626-451-420; 082-627-988-327-269; 084-625-648-440-007; 087-522-531-031-418; 087-902-446-328-975; 089-073-683-485-98X; 090-696-964-916-092; 092-259-074-911-342; 095-466-037-337-282; 096-754-826-524-534; 097-402-193-588-956; 098-275-661-914-829; 099-361-117-108-097; 099-671-859-806-373; 100-827-956-705-672; 100-926-840-355-790; 113-682-442-621-962; 114-137-306-956-189; 114-179-052-783-526; 116-344-266-423-971; 117-263-313-301-937; 118-501-446-101-880; 120-283-161-263-818; 122-364-330-286-496; 122-694-663-345-679; 122-827-252-276-011; 125-152-362-379-413; 125-973-766-132-706; 127-194-549-407-099; 127-861-322-764-928; 128-401-368-999-588; 129-352-688-685-084; 135-468-293-524-966; 135-524-681-464-591; 135-961-457-399-25X; 143-055-982-047-880; 143-863-443-774-62X; 147-491-915-347-61X; 149-711-693-971-306; 150-426-214-455-164; 154-863-189-529-643; 156-415-541-949-588; 157-230-057-653-561; 159-144-327-905-178; 161-111-813-714-626; 162-931-193-006-142; 169-016-605-957-637; 169-209-413-958-29X; 173-325-951-027-823; 174-655-784-291-800; 179-099-340-881-794; 179-608-372-698-452; 180-879-844-348-312; 185-824-570-750-091; 188-723-132-512-532; 197-761-550-454-658,0,true,cc-by,gold -070-154-979-490-520,Benefits and challenges of using AI in heritage education,2024-12-30,2024,journal article,EthAIca,30727952,AG Editor (Argentina),,Guillermo Alfredo Jiménez Pérez,"Introduction: This research analyzes the application of artificial intelligence (AI) in heritage education between 2019 and 2022, focusing on its benefits and challenges. Methodology: A bibliometric methodology combining quantitative and qualitative techniques is employed, using databases such as Web of Science, Scopus, and Google Scholar. The search strategy focuses on key terms such as AI, heritage education, benefits, and challenges. The data is processed with tools such as Bibliometrix and VOSviewer to identify trends, collaborative networks, and emerging themes. Results: The study provides a structured overview of the field, highlighting research gaps and future opportunities. Conclusions: The study provides a structured overview of the field, highlighting research gaps and future opportunities.",3,,102,,,,,,,,http://dx.doi.org/10.56294/ai2024102,,10.56294/ai2024102,,,0,000-166-783-281-486; 000-709-573-118-101; 020-102-739-944-820; 020-714-161-651-809; 021-197-477-706-347; 022-308-781-967-838; 024-608-154-449-131; 025-740-907-842-144; 029-219-369-826-726; 032-680-184-625-315; 034-623-958-881-147; 038-876-853-615-265; 040-276-182-153-516; 040-688-942-204-736; 043-065-758-271-398; 043-130-750-103-101; 046-212-857-293-783; 047-698-646-780-118; 047-753-913-919-065; 049-735-524-640-435; 056-373-690-552-121; 057-179-840-123-54X; 060-008-658-628-287; 061-996-985-586-718; 069-192-354-568-270; 079-927-374-872-488; 083-812-330-204-642; 086-044-580-403-791; 088-914-871-430-625; 094-391-402-055-700; 095-620-510-989-773; 097-762-220-677-436; 099-852-826-146-033; 102-039-898-085-289; 104-734-424-241-048; 106-917-683-264-740; 117-940-537-099-761; 119-102-735-043-654; 123-600-674-223-112; 127-910-239-161-841; 131-960-268-509-560; 137-927-516-271-883; 138-954-680-119-517; 144-613-171-506-852; 157-963-905-956-45X; 162-431-656-405-262; 165-466-020-691-565; 172-376-247-688-007; 189-480-543-922-168; 195-532-869-572-072,0,false,, -070-275-261-626-899,Research trends in management of cultural and creative industries in the Ibero-American network,2021-12-09,2021,journal article,Journal of Cultural and Creative Industries,26608294,Universidad Miguel Hernandez de Elche,,Liudmila Sycheva; Lirios Alos-Simó; Antonio José Verdú-Jover,"Although cultural and creative industries are considered as drivers of social and economic progress, they have received little attention from a managerial perspective in the Ibero-American context. To develop more in-depth knowledge of this topic, we conducted a bibliometric analysis of cultural and creative industries management in Ibero-American countries, using the Scopus database and VOSviewer and Bibliometrix R tools. The findings show that, despite general growing interest in recent years, exploration of the Ibero-American network is still in the early stages. The results also shed light on the complex, multifaceted relationship between cultural and creative industries management and innovation. Finally, sustainability and digitization were identified as the most prominent research trends.",2,1,,,Digitization; Scopus; Creative industries; Context (archaeology); Sustainability; Perspective (graphical); Knowledge management; Business; Political science; Geography; Engineering; Computer science; Archaeology; MEDLINE; Telecommunications; Ecology; Artificial intelligence; Law; Biology,,,,,https://revistas.innovacionumh.es/index.php/JCCI/article/download/1433/1644 https://doi.org/10.21134/jcci.v2i.1433,http://dx.doi.org/10.21134/jcci.v2i.1433,,10.21134/jcci.v2i.1433,,,0,,2,true,,bronze -070-436-595-705-559,"Dynamicity, emerging patterns, and spatiotemporal trends of scientific production on the use of activated carbon in oral health: a scientometric study.",2023-09-16,2023,journal article,BMC oral health,14726831,Springer Science and Business Media LLC,United Kingdom,Frank Mayta-Tovalino; Fran Espinoza-Carhuancho; Daniel Alvitez-Temoche; Cesar Mauricio-Vilchez; Arnaldo Munive-Degregori; John Barja-Ore; Josmel Pacheco-Mendoza,"The use of activated carbon (AC) in oral hygiene products has gained significant interest; however, its potential benefits for oral health remain uncertain. This study aimed to conduct a scientometric analysis to examine the dynamicity, emerging patterns, and trends over time in scientific production concerning the use of AC in oral health.; The Web of Science database was searched for articles published between 2005 and 2022. Various bibliometric indicators, including the H-index, annual growth, Lotka's law, Bradford's law, and Sankey diagram, were used for data analysis. Overlay maps, timezone visualization, and three field plots were used to evaluate visualization patterns, time-temporal relationships, and trends. Information retrieval process was performed on March 11, 2023.; The analysis revealed that only six studies constituted the top references with the highest number of citations in recent years, with Brooks' 2017 study demonstrating the most significant increase in citation. The dual-map overlay demonstrated a close citation relationship between cluster 4 (Molecular Biology Immunology) and the areas of Environmental, Toxicology, and Nutrition. The visualization graph of publication patterns indicated the journals that accumulated the highest number of citations during the study period.; This scientometric study provides valuable insights into the use of AC in oral health and its impact on the field of dentistry. It determines the most productive journals, authors, and countries with the greatest influence. AC effectively removes pollutants and is gaining interest for use in dental effluent treatment. Thus, it may be a viable option for professionals.; © 2023. BioMed Central Ltd., part of Springer Nature.",23,1,668,,Medicine; Bibliometrics; Visualization; Oral and maxillofacial surgery; Citation; Science Citation Index; Data science; Environmental health; Data mining; Computer science; Dentistry; Library science,Activated carbon; Bibliometrix; Oral health; Scientometric study; Web of Science,"Humans; Charcoal; Oral Health; Cognition; Databases, Factual; Environmental Pollutants",Charcoal; Environmental Pollutants,,https://bmcoralhealth.biomedcentral.com/counter/pdf/10.1186/s12903-023-03375-3 https://doi.org/10.1186/s12903-023-03375-3,http://dx.doi.org/10.1186/s12903-023-03375-3,37715190,10.1186/s12903-023-03375-3,,PMC10504778,0,019-816-363-324-963; 028-353-334-397-627; 035-895-332-710-480; 046-277-252-095-095; 050-997-854-134-40X; 051-978-519-877-946; 054-178-560-303-649; 058-129-144-774-032; 115-817-143-312-092; 174-193-923-651-578; 181-988-274-743-407,1,true,"CC BY, CC0",gold -070-575-455-023-61X,A Bibliometric Analysis on Exploring the Emerging Trends and Influence of Green Finance in India Using Bibliometrix,2024-11-02,2024,book chapter,"Studies in Systems, Decision and Control",21984182; 21984190,Springer Nature Switzerland,,Neerupa Chauhan; Nidhi Raj Gupta; Annie Stephen; N. Sony,,,,1177,1191,Regional science; Geography,,,,,,http://dx.doi.org/10.1007/978-3-031-67890-5_105,,10.1007/978-3-031-67890-5_105,,,0,000-649-596-199-221; 002-372-060-559-130; 011-099-203-697-031; 011-365-400-168-234; 021-976-887-009-301; 026-502-051-655-423; 027-526-716-959-820; 028-359-940-456-145; 030-419-977-866-109; 036-205-994-002-550; 047-605-444-752-252; 048-384-199-359-544; 048-977-564-255-705; 061-895-972-256-020; 062-728-107-073-017; 069-846-794-362-719; 073-330-440-903-482; 075-941-206-422-344; 096-173-381-586-285; 104-480-393-564-807; 107-955-759-861-634; 115-988-519-953-362; 123-061-934-711-949; 129-167-747-173-982; 132-516-574-832-767; 136-053-519-480-970; 141-407-090-706-370; 141-957-967-191-593; 148-843-640-379-286; 154-448-858-013-380; 164-420-698-001-45X; 194-473-188-843-216,1,false,, -071-240-259-114-671,How to Build a Bioeconomic Food System: A Thematic Review,2024-06-19,2024,journal article,Circular Economy and Sustainability,2730597x; 27305988,Springer Science and Business Media LLC,,Diego Durante Mühl; Mariana Vargas Braga da Silva; Letícia de Oliveira,,4,3,1697,1727,Thematic map; Food systems; Business; Food security; Geography; Cartography; Agriculture; Archaeology,,,,Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,,http://dx.doi.org/10.1007/s43615-024-00387-1,,10.1007/s43615-024-00387-1,,,0,000-041-407-182-960; 002-052-422-936-00X; 006-110-047-217-115; 007-159-731-641-426; 007-875-175-780-819; 011-094-467-617-709; 012-203-364-372-143; 012-657-805-834-988; 012-865-661-706-544; 013-507-404-965-47X; 017-750-600-412-958; 018-526-878-267-847; 021-921-722-606-02X; 022-454-358-531-135; 023-353-098-376-40X; 023-929-123-970-005; 024-089-143-464-721; 024-370-296-442-835; 025-536-116-070-813; 030-704-541-071-025; 034-487-142-521-84X; 043-042-622-653-942; 044-165-459-344-811; 045-160-857-121-190; 045-643-900-040-510; 046-272-160-744-200; 046-992-864-415-70X; 048-878-823-324-960; 049-246-477-604-628; 050-609-067-982-963; 052-281-286-547-810; 053-750-619-113-806; 056-891-511-211-170; 057-803-697-074-453; 058-159-942-365-177; 060-110-039-971-60X; 065-010-405-236-060; 065-443-270-229-704; 074-576-881-949-44X; 075-611-088-489-115; 076-168-956-173-544; 076-261-519-912-093; 076-640-379-526-907; 079-794-897-776-309; 086-707-835-623-919; 088-884-432-819-802; 093-348-153-801-687; 095-155-038-075-626; 096-000-066-332-917; 098-129-801-227-241; 101-752-490-869-458; 103-013-079-307-539; 104-002-286-258-189; 106-908-645-138-263; 110-120-168-923-71X; 113-309-811-175-705; 115-237-323-658-153; 118-018-624-797-797; 119-957-301-688-731; 123-233-409-443-120; 125-581-793-636-747; 128-553-070-836-965; 129-447-707-280-894; 132-730-328-243-788; 133-710-328-408-579; 135-954-058-768-585; 139-896-241-519-205; 141-200-607-894-303; 141-501-803-168-914; 142-324-214-371-764; 142-577-256-469-749; 153-936-915-307-411; 154-289-515-888-577; 158-171-767-454-371; 165-607-302-660-317; 169-588-354-270-673; 186-990-610-996-61X,2,false,, -071-406-784-462-444,Estudo bibliométrico sobre Rankings Universitários,2021-05-21,2021,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Marisa Cubas Lozano; Denilson de Oliveira Sarvo,"A intenção deste trabalho foi caracterizar a produção científica sobre Rankings Universitários disponível na Web of Science e Scopus. Para isso foi usada a técnica de análise bibliometria e as ferramentas bibliometrix, VOSviewer, Mendeley e Excel.",,,,,Political science,,,,,https://zenodo.org/record/5199523,http://dx.doi.org/10.5281/zenodo.5199523,,10.5281/zenodo.5199523,,,0,,0,true,cc-by,gold -071-936-922-783-616,Bibliometrix: Primeros pasos y técnicas avanzadas con BiblioShiny App,,,book,,,,,Daniel Torres-Salinas,,,,,,,,,,,https://digibug.ugr.es/handle/10481/64961,http://dx.doi.org/10.5281/zenodo.4327614,,10.5281/zenodo.4327614,3110913502,,0,,0,false,, -071-994-956-716-310,A bibliometric analysis of biochar application in wastewater treatment from 2000 to 2021,2023-06-19,2023,journal article,International Journal of Environmental Science and Technology,17351472; 17352630,Springer Science and Business Media LLC,"Iran, Islamic Republic of",H. Nan; L. Wang; D. Luo; Y. Zhang; G. Liu; C. Wang,,20,12,13957,13974,Biochar; Web of science; Environmental science; Work (physics); Subject (documents); Sewage treatment; Wastewater; Bibliometrics; Citation; China; Library science; Engineering; Waste management; Computer science; Political science; Environmental engineering; Law; Mechanical engineering; MEDLINE; Pyrolysis,,,,,,http://dx.doi.org/10.1007/s13762-023-05030-4,,10.1007/s13762-023-05030-4,,,0,000-969-696-948-456; 003-037-832-661-660; 003-202-154-487-013; 004-841-013-190-731; 008-530-625-967-887; 009-160-645-655-013; 009-483-455-559-780; 009-749-282-682-793; 010-636-553-020-914; 014-160-460-932-96X; 015-567-974-859-182; 016-164-478-595-085; 016-191-077-484-580; 017-636-456-445-19X; 019-275-902-565-899; 020-217-705-964-364; 020-469-381-218-146; 027-628-839-554-687; 028-532-154-294-667; 029-276-514-226-147; 037-351-652-818-172; 037-741-470-831-206; 037-745-015-339-963; 039-295-271-706-125; 039-508-079-095-56X; 040-114-687-630-259; 043-772-916-356-411; 046-934-011-466-016; 049-319-318-135-603; 051-705-895-162-481; 052-120-065-557-583; 052-490-888-790-448; 053-052-672-637-846; 055-586-052-035-560; 059-743-294-905-567; 061-717-838-199-65X; 063-141-953-409-740; 063-220-495-855-553; 074-668-239-375-539; 074-725-168-468-380; 075-869-092-816-914; 077-130-646-257-286; 079-679-789-158-219; 080-562-540-546-212; 087-509-275-347-678; 088-226-808-526-06X; 089-465-596-067-432; 097-538-363-267-542; 099-613-958-605-766; 099-813-326-947-991; 100-963-402-341-412; 101-571-880-727-612; 102-456-386-933-114; 105-337-581-994-921; 109-500-774-147-561; 112-637-909-408-534; 117-269-870-711-004; 119-795-167-756-406; 122-041-219-729-563; 125-587-477-421-469; 127-137-769-444-886; 133-857-469-830-454; 138-053-913-794-217; 151-971-244-082-768; 155-111-263-445-099; 157-406-281-502-641; 160-979-080-630-23X; 188-880-994-718-875; 194-098-719-255-818; 197-927-666-939-611; 198-766-502-555-525,15,false,, -072-269-370-224-006,The scientific outcome in the domain of grey literature: bibliometric mapping and visualisation using the R-bibliometrix package and the VOSviewer,2022-12-20,2022,journal article,Library Hi Tech,07378831; 2054166x,Emerald,United Kingdom,Javaid Ahmad Wani; Shabir Ahmad Ganaie,"PurposeThe current study aims to map the scientific output of grey literature (GL) through bibliometric approaches.Design/methodology/approachThe source for data extraction is a comprehensive “indexing and abstracting” database, “Web of Science” (WOS). A lexical title search was applied to get the corpus of the study – a total of 4,599 articles were extracted for data analysis and visualisation. Further, the data were analysed by using the data analytical tools, R-studio and VOSViewer.FindingsThe findings showed that the “publications” have substantially grown up during the timeline. The most productive phase (2018–2021) resulted in 47% of articles. The prominent sources were PLOS One and NeuroImage. The highest number of papers were contributed by Haddaway and Kumar. The most relevant countries were the USA and UK.Practical implicationsThe study is useful for researchers interested in the GL research domain. The study helps to understand the evolution of the GL to provide research support further in this area.Originality/valueThe present study provides a new orientation to the scholarly output of the GL. The study is rigorous and all-inclusive based on analytical operations like the research networks, collaboration and visualisation. To the best of the authors' knowledge, this manuscript is original, and no similar works have been found with the research objectives included here.",42,1,309,330,Timeline; Visualization; Originality; Computer science; Search engine indexing; Data science; Domain (mathematical analysis); Data extraction; Bibliometrics; Information retrieval; World Wide Web; Data mining; Geography; Social science; Sociology; Qualitative research; Mathematical analysis; Mathematics; Archaeology; MEDLINE; Political science; Law,,,,,,http://dx.doi.org/10.1108/lht-01-2022-0012,,10.1108/lht-01-2022-0012,,,0,000-921-109-125-242; 002-052-422-936-00X; 003-762-456-646-396; 004-859-593-662-226; 005-657-459-454-849; 008-133-636-020-868; 009-565-172-617-580; 010-000-021-135-215; 013-507-404-965-47X; 015-692-170-714-052; 022-460-432-360-639; 022-762-430-508-402; 023-620-543-445-199; 023-649-468-319-641; 024-145-440-501-14X; 027-434-527-905-948; 028-118-437-871-790; 028-728-563-956-910; 028-790-718-552-716; 029-406-143-413-308; 029-997-349-513-088; 030-711-798-010-979; 030-730-861-715-175; 033-333-343-247-471; 037-188-398-844-799; 037-255-661-584-793; 040-436-150-461-602; 043-766-152-202-285; 043-805-882-100-183; 044-776-532-451-668; 045-899-177-392-005; 046-164-962-633-838; 046-521-492-268-604; 046-992-864-415-70X; 050-443-298-858-372; 052-589-810-129-537; 054-925-712-387-420; 062-476-974-501-19X; 065-483-715-894-317; 065-771-228-791-747; 070-312-064-823-236; 070-333-413-090-791; 070-488-884-958-733; 073-020-817-673-290; 073-775-823-470-313; 074-689-637-760-304; 076-097-063-069-680; 076-920-753-846-000; 077-032-197-671-537; 079-201-503-418-87X; 081-278-486-885-35X; 082-433-765-548-501; 087-899-979-842-358; 088-390-346-826-651; 090-874-327-921-285; 093-876-759-833-113; 094-748-354-405-137; 095-450-422-324-801; 096-829-963-582-216; 098-536-916-733-505; 101-804-785-452-790; 112-169-102-801-357; 112-535-936-577-897; 114-705-440-845-589; 120-731-758-071-612; 121-087-248-657-99X; 122-018-985-608-01X; 127-696-906-945-347; 128-907-324-795-434; 133-092-884-213-275; 133-160-286-607-487; 141-200-607-894-303; 144-069-719-135-65X; 144-840-498-048-902; 146-051-834-619-411; 174-750-199-363-637; 175-842-815-225-794; 182-347-456-782-286; 184-298-594-057-116; 189-834-794-107-032,13,false,, -072-423-744-930-144,Hydro-meteorological hazards and role of ICT during 2010-2019: A scientometric analysis,2020-08-15,2020,journal article,Earth Science Informatics,18650473; 18650481,Springer Science and Business Media LLC,Germany,Mandeep Kaur; Sandeep K. Sood,,13,4,1201,1223,Business; Ontology (information science); Emerging technologies; Data science; Hazard management; Research areas; Information and Communications Technology; Big data; Cloud computing; Scopus,,,,,https://link.springer.com/article/10.1007/s12145-020-00495-0 https://dblp.uni-trier.de/db/journals/esi/esi13.html#KaurS20a,http://dx.doi.org/10.1007/s12145-020-00495-0,,10.1007/s12145-020-00495-0,3049519724,,0,000-792-009-951-071; 002-052-422-936-00X; 004-895-009-373-387; 012-310-893-728-241; 013-507-404-965-47X; 016-321-766-251-646; 020-394-396-665-56X; 024-715-980-761-331; 026-287-433-218-473; 027-163-067-825-91X; 047-134-478-431-993; 077-781-273-891-768; 087-088-140-755-970; 101-071-574-340-232; 101-972-760-845-101; 107-115-687-998-575; 108-865-996-275-337; 115-806-102-099-500; 116-722-337-296-742; 126-977-092-531-632; 133-331-264-009-527; 148-039-707-506-220; 162-123-368-418-70X,14,false,, -072-468-163-840-780,Bibliometric study about chaotic cryptography in developing countries,2022-05-28,2022,conference proceedings article,"2022 IEEE 9th International Conference on Sciences of Electronics, Technologies of Information and Telecommunications (SETIT)",,IEEE,,Salma Ben Mamia; Judita Kasperiuniene; William Puech; Kais Bouallegue,"In this paper, an analyse of scientific journal articles related to chaotic cryptography from 2015 to 2021, is presented. In doing so, the study uses the Web of Science Core Collection database to analyze the data. 'biblioshiny' a web-interface of the 'bibliometrix 3.0' package of R-studio has been deployed to conduct bibliometric analysis. Also, a graphical mapping of the bibliometric material by using the visualization of similarities (VOS) viewer software, was developed. The study relies on the proposed approach to explore the influence of developing countries on Chaos-based encryption. We found out that developing countries are the most active on chaotic cryptography.",4,,291,298,Cryptography; Computer science; Chaotic; Computer security; Artificial intelligence,,,,,,http://dx.doi.org/10.1109/setit54465.2022.9875676,,10.1109/setit54465.2022.9875676,,,0,001-187-851-931-671; 002-052-422-936-00X; 002-558-853-536-014; 003-296-613-339-862; 006-044-317-089-377; 006-564-247-336-203; 010-195-490-212-474; 011-055-116-236-021; 012-278-725-096-938; 017-447-530-521-101; 018-664-087-651-821; 019-473-684-087-928; 023-927-221-065-800; 027-406-540-345-844; 031-531-051-422-754; 032-653-148-624-135; 033-870-772-724-145; 035-910-741-165-578; 036-706-669-588-178; 036-716-836-180-188; 038-225-853-246-86X; 039-314-825-483-850; 040-669-446-107-052; 045-993-333-977-461; 051-608-426-073-000; 053-395-405-521-798; 054-183-321-014-213; 054-884-349-654-273; 056-546-785-316-853; 057-932-809-558-147; 074-094-965-665-784; 075-958-388-920-184; 088-985-305-303-195; 091-452-578-437-419; 100-629-449-459-078; 103-559-128-393-416; 108-637-284-458-958; 115-328-798-870-442; 123-202-581-406-928; 124-314-387-448-158; 124-814-014-669-995; 126-358-435-490-631; 127-912-941-387-452; 130-057-480-639-007; 145-834-288-609-893; 158-972-796-703-277; 166-437-056-167-910; 177-151-154-203-001; 192-080-010-688-773,0,false,, -072-577-214-190-312,Bibliometric analysis of digital transformation on organization design,,2025,journal article,Anali Ekonomskog fakulteta u Subotici,03502120; 26834162,Centre for Evaluation in Education and Science (CEON/CEES),,Katarina Božić,"Digital transformation has become a key driver of change in modern organizations, reshaping their design and way of functioning. This paper aims to investigate how digitalization has impacted organizations and their organizational design, using a bibliometric approach to analyze research trends in this area. Using the Bibliometrix software package in the R programming language, bibliographic data analysis was performed in order to identify the most influential authors, key topics and future research directions. The study analyzed a dataset of 175 publications in English from the period 2000-2023, sourced from Web of Science Core Collection database, focusing on research articles discussing digital transformation and organizational design. Bibliometrix application was used to perform the bibliometric analysis, which included co-citation, keyword analysis, and thematic mapping to reveal core trends and influential papers in the literature. The study reveals that digital transformation significantly alters organizational structure and role distribution, often decentralizing power and increasing flexibility within companies. These findings align with theories on dynamic capabilities and suggest that further research could focus on how digital transformation supports agility in organizational design, providing practical insights for adapting organizations to digital era demands. Future research on the impact of digital transformation on organizational design could focus on artificial intelligence integration, digital skill requirements, hybrid structures, blockchain technology, as well as challenges and strategies for managing data security and privacy.",,53,125,148,,,,,,,http://dx.doi.org/10.5937/aneksub2500003b,,10.5937/aneksub2500003b,,,0,000-671-195-045-53X; 001-670-329-471-342; 006-159-491-691-662; 006-853-764-030-334; 013-507-404-965-47X; 033-014-253-880-814; 034-837-265-172-536; 037-560-399-558-733; 040-739-455-073-115; 043-362-437-537-061; 045-340-542-478-337; 045-993-333-977-461; 046-169-811-715-505; 046-992-864-415-70X; 047-534-231-759-666; 049-157-465-690-19X; 049-730-244-126-973; 051-660-674-689-929; 054-460-983-040-392; 054-636-524-831-888; 055-716-315-806-05X; 063-694-233-570-544; 064-358-836-347-994; 068-380-376-705-40X; 069-424-875-677-042; 070-610-414-654-686; 072-191-900-118-490; 074-074-071-012-84X; 074-777-878-485-681; 086-341-446-522-651; 088-188-462-623-502; 089-376-857-531-05X; 096-351-914-525-506; 100-294-259-882-658; 102-736-564-074-217; 103-207-090-026-127; 104-321-875-291-655; 123-292-731-975-635; 125-028-670-643-88X; 130-057-480-639-007; 133-754-946-021-595; 142-951-302-278-490; 143-936-693-364-687; 160-681-081-707-954; 179-608-372-698-452; 191-807-981-122-172; 191-929-042-152-926; 193-573-966-807-425,0,true,cc-by,gold -072-624-487-410-594,Educação para as alterações climáticas: uma revisão bibliométrica na Web of Science,2024-02-01,2024,journal article,Revista Brasileira de Educação Ambiental (RevBEA),19811764; 19800118,Universidade Federal de Sao Paulo,,Ricardo Ramos; Maria José Rodrigues; Nuno Aluai,"Apesar das evidências apontarem para um destino inóspito causado pelas alterações climáticas antropogénicas, irrefutavelmente relacionadas com os nossos hábitos de consumo, há uma carência de investigações acerca da educação para este problema. Como tal, realizámos uma análise bibliométrica quali-quantitativa na base de dados Web of Science. Segundo os parâmetros utilizados 42 publicações eram elegíveis e, através do Bibliometrix R, percebemos que ocorreu um aumento, nos últimos cinco anos, na produção científica no tema supramencionado. Não obstante, reitera-se a necessidade de se aprofundarem os estudos sobre esta problemática, que pela sua premência e complexidade, urge encontrar novas soluções educativas.",19,1,86,101,Political science; Web of science; MEDLINE; Law,,,,,https://periodicos.unifesp.br/index.php/revbea/article/download/15430/11444 https://doi.org/10.34024/revbea.2024.v19.15430 https://bibliotecadigital.ipb.pt/bitstream/10198/29577/1/Artigo5.pdf https://hdl.handle.net/10198/29577,http://dx.doi.org/10.34024/revbea.2024.v19.15430,,10.34024/revbea.2024.v19.15430,,,0,,0,true,,gold -072-881-448-182-565,Precision and reliability study of hospital infusion pumps: a systematic review.,2023-03-17,2023,journal article,Biomedical engineering online,1475925x,Springer Science and Business Media LLC,United Kingdom,Mayla Dos S Silva; Joabe Lima Araújo; Gustavo A M de A Nunes; Mário Fabrício F Rosa; Glécia V da Silva Luz; Suélia de S R F Rosa; Antônio Piratelli-Filho,"Infusion Pumps (IP) are medical devices that were developed in the 1960s and generate fluid flow at pressures higher than that of normal blood pressure. Various hospital sectors make use of them, and they have become indispensable in therapies requiring continuity and precision in the administration of medication and/or food. As they are classified Class III (high risk) equipment, their maintenance is crucial for proper performance of the device, as well as patient and operator safety. The principal consideration of the pump is the volume infused, and the device demands great attention to detail when being calibrated. A lack of necessary care with this equipment can lead to uncertainty in volume and precision during the administration of substances. Because of this, it is essential to evaluate its reliability, to prevent possible failures at time of execution. This control aims at the quality of the intended infusion result, becoming an indication of quality.; This systematic review summarizes studies done over the last 10 years (2011 to December 2021) that address the reliability and accuracy of hospital infusion pumps, in order to identify planning of maintenance and/or other techniques used in management of the equipment. The Prisma method was applied and the databases utilized were Embase, MEDLINE/Pubmed, Web of Science, Scopus, IEEE Xplore, and Science Direct. In addition, similar reviews were studied in Prospero and the Cochrane Library. For data analysis, softwares such as Mendeley, Excel, RStudio, and VOSviewer were used, and Robvis helped in plotting risk of bias results for studies performed with Cochrane tools.; The six databases selected produced 824 studies. After applying eligibility criteria (inclusion and exclusion), removing duplicates, and applying filters 1 and 2, 15 studies were included in the present review. It was found that the most relevant sources came from the Institute of Electrical and Electronics Engineers (IEEE) and that the most relevant keywords revolved around the terms (""device failure"", ""infusion pumps"", ""adverse effects"", ""complications"", etc.). These results made clear that there remains substantial room for improvement as it relates to the study of accuracy and reliability of infusion.; We verified that the reliability and precision analysis of hospital infusion pumps need to be performed in a more detailed and consistent way. New developments, considering the model and IP specification, are intended, clearly explaining the adopted methodology.; © 2023. The Author(s).",22,1,26,,Computer science; Cochrane Library; Reliability (semiconductor); Systematic review; Infusion pump; Patient safety; MEDLINE; Medicine; Reliability engineering; Quality (philosophy); Scopus; Health care; Surgery; Engineering; Randomized controlled trial; Power (physics); Philosophy; Physics; Epistemology; Quantum mechanics; Political science; Law; Economics; Radiology; Economic growth,Infusion pumps; Medical equipment; Precision; Reliability,Humans; Reproducibility of Results; Hospitals; Infusion Pumps,,"DPG, University of Brasília, Brazil; Scholarship holder of the Coordination for the Improvement of Higher Education Personnel, CAPES, Brazil; Productivity Scholarship Designer. Tech and Innovative Extension of CNPq - Level 2",https://biomedical-engineering-online.biomedcentral.com/counter/pdf/10.1186/s12938-023-01088-w https://doi.org/10.1186/s12938-023-01088-w,http://dx.doi.org/10.1186/s12938-023-01088-w,36932393,10.1186/s12938-023-01088-w,,PMC10023007,0,001-071-882-061-694; 003-467-305-440-129; 006-984-888-662-587; 010-092-865-730-859; 017-242-155-569-760; 017-300-737-144-757; 017-715-183-258-190; 018-826-415-044-449; 020-520-953-714-585; 023-117-606-992-58X; 025-032-478-264-827; 026-845-556-749-649; 027-128-762-535-54X; 027-855-823-759-581; 035-518-039-082-880; 036-934-530-995-857; 048-699-614-802-424; 053-363-256-908-73X; 055-309-417-647-610; 057-285-454-599-696; 061-166-027-974-693; 066-497-617-453-570; 082-939-140-822-150; 085-356-405-914-953; 087-073-192-354-990; 088-471-392-526-523; 097-676-418-062-743; 102-798-155-320-142; 105-785-789-276-477,9,true,"CC BY, CC0",gold -073-394-778-695-708,A bibliometric analysis of the application of the PI3K-AKT-mTOR signaling pathway in cancer.,2024-05-06,2024,journal article,Naunyn-Schmiedeberg's archives of pharmacology,14321912; 00281298,Springer Science and Business Media LLC,Germany,Zhengzheng Deng; Qiancheng Qing; Bo Huang,,397,10,7255,7272,PI3K/AKT/mTOR pathway; Protein kinase B; Bibliometrics; Cancer; Cancer research; Medicine; Biology; Apoptosis; Library science; Computer science; Internal medicine; Biochemistry,Autophagy; Bibliometrics; Cancer; PI3K-AKT-mTOR; Pathway inhibitors,Animals; Humans; Antineoplastic Agents/therapeutic use; Bibliometrics; Neoplasms/drug therapy; Phosphatidylinositol 3-Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction; TOR Serine-Threonine Kinases/metabolism,"Antineoplastic Agents; MTOR protein, human; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases",,,http://dx.doi.org/10.1007/s00210-024-03112-9,38709265,10.1007/s00210-024-03112-9,,,0,000-024-459-241-112; 000-246-967-745-521; 000-667-231-896-402; 000-991-707-109-30X; 001-175-128-936-758; 001-810-759-240-52X; 002-052-422-936-00X; 004-502-567-999-413; 004-809-022-832-425; 005-349-394-824-487; 005-935-944-845-736; 006-412-566-909-993; 006-624-377-927-10X; 007-721-202-802-285; 008-703-137-529-928; 008-977-664-662-307; 010-194-028-604-828; 011-073-510-950-257; 011-414-950-676-127; 011-591-653-987-751; 011-648-690-686-901; 011-700-074-335-046; 012-781-922-366-608; 013-385-059-503-772; 013-627-399-427-920; 015-368-189-983-602; 017-113-746-846-917; 018-303-446-941-73X; 018-319-326-134-278; 018-416-905-749-52X; 018-836-446-084-370; 019-337-569-252-418; 019-483-014-736-983; 020-948-275-810-806; 022-030-971-543-40X; 024-373-245-816-597; 024-730-564-155-207; 025-627-742-475-424; 026-388-803-872-185; 026-395-112-558-483; 026-560-708-832-611; 026-646-521-253-318; 026-678-226-463-394; 027-160-190-736-417; 027-167-674-264-024; 027-182-985-291-973; 027-870-001-438-311; 029-624-788-210-642; 029-854-882-938-625; 030-213-677-122-411; 030-329-378-068-384; 030-545-811-745-419; 030-698-376-681-234; 031-208-887-186-480; 034-340-556-070-19X; 035-833-111-503-214; 036-294-334-443-542; 036-548-975-395-859; 036-779-909-173-869; 037-351-728-930-823; 037-580-572-212-25X; 040-327-423-959-949; 041-262-376-388-865; 041-900-934-057-109; 042-687-911-387-646; 043-236-089-416-951; 044-483-498-686-690; 045-034-712-545-032; 045-038-629-466-526; 045-334-595-619-657; 046-597-891-237-988; 046-624-833-541-771; 047-284-460-860-697; 049-867-608-561-237; 050-371-256-500-33X; 051-565-555-533-846; 052-582-107-806-725; 052-615-303-173-310; 053-753-889-136-278; 055-499-500-519-740; 056-419-562-493-340; 057-086-129-494-063; 057-557-495-041-054; 062-559-640-200-817; 064-400-499-357-900; 065-090-205-313-829; 065-666-739-418-421; 066-175-656-978-351; 069-097-641-306-649; 069-408-907-984-398; 071-878-836-294-733; 072-042-364-654-214; 075-911-877-145-061; 076-072-444-074-570; 077-681-611-292-453; 080-338-845-253-502; 081-251-371-560-985; 081-585-527-149-456; 081-705-935-657-007; 086-934-649-395-844; 087-465-970-300-554; 088-291-558-095-308; 089-543-472-073-700; 090-177-120-166-012; 094-071-320-226-972; 095-032-100-574-670; 096-107-212-845-631; 097-735-211-714-123; 099-302-861-552-225; 100-573-717-049-287; 101-752-490-869-458; 103-619-991-599-943; 104-341-461-187-637; 107-262-715-167-286; 107-483-302-885-238; 107-527-195-365-254; 109-855-070-022-544; 110-930-979-203-091; 113-987-612-539-003; 116-426-589-771-355; 119-980-221-845-35X; 127-943-794-301-912; 129-547-482-038-156; 133-268-581-580-20X; 134-943-503-100-760; 142-402-263-564-547; 145-027-472-747-769; 154-399-282-361-201; 154-692-893-398-76X; 160-041-961-327-129; 162-441-813-447-220; 165-650-072-863-808; 167-548-944-569-625; 171-241-311-634-579; 177-648-266-308-557; 194-233-575-335-083; 198-886-361-559-413,5,false,, -073-494-189-328-65X,A Global Bibliometric Analysis of Hallux Valgus Research (1999-2019).,2020-10-08,2020,journal article,The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons,15422224; 10672516,Academic Press Inc.,United Kingdom,Gabriel Ferraz Ferreira; Kelly Cristina Stéfani,"Abstract Hallux valgus (HV) is a very common deformity among foot disorders, therefore attracting strong interest from foot and ankle surgeons. We investigated publication trends on HV in the literature. The analysis was conducted through an electronic search of the Web of Science database for publications between 1999 and 2019, studying the data of origin through bibliometrics. The following search string was utilized: TI = (hallux valgus* OR hallux abductovalgus*) with filters for the English language and documents in article format. The “Bibliometrix” package of R software was used for the bibliometric analysis, and the VOSviewer was used to create graphs. A total of 789 articles were found in the electronic search, with 2,723 cited articles. The most common Web of Science category was Orthopedics (83.0%), and Coughlin M.J. was the main researcher in this field with the largest number of publications (17). The United States led in terms of the number of published articles (26.7%). An increase in the number of publications over time was noted, with 2016 being the year with the highest number of articles (78). The journal with the most articles was Foot and Ankle International, with 35.2% of the publications. The number of published studies on HV has increased rapidly since 2012. The United States ranks first in related research worldwide. The journal with the most articles was Foot and Ankle International.",60,3,501,506,Surgery; Foot (unit); Library science; Bibliometrics; Bibliographic coupling; Ankle; Foot deformity; Valgus; Hallux abductovalgus; Bibliometric analysis; Medicine,Bibliometrix®; Bradford model; Web of Science; bibliographic coupling; collaborative network; foot deformity; hallux; publication,"Bibliometrics; Databases, Factual; Hallux Valgus/surgery; Humans; Orthopedic Procedures; Orthopedics; United States",,,https://europepmc.org/article/MED/33573904 https://www.sciencedirect.com/science/article/pii/S1067251620303847 https://www.ncbi.nlm.nih.gov/pubmed/33573904,http://dx.doi.org/10.1053/j.jfas.2020.09.016,33573904,10.1053/j.jfas.2020.09.016,3091961186,,0,001-824-683-189-605; 002-052-422-936-00X; 003-814-986-372-435; 004-082-671-384-437; 011-238-980-718-80X; 013-507-404-965-47X; 015-516-330-361-688; 015-615-811-044-097; 016-007-823-151-129; 017-349-318-774-487; 020-591-787-432-942; 024-509-040-818-353; 035-079-875-180-986; 047-883-412-960-858; 057-058-693-769-402; 057-414-915-301-935; 063-050-462-225-169; 063-441-759-076-860; 065-986-421-249-595; 073-641-465-192-881; 088-908-268-737-277; 127-645-778-235-147; 129-163-268-633-023; 138-561-175-358-392; 144-402-048-146-038; 146-889-441-198-571; 151-066-640-236-837; 156-415-541-949-588; 170-336-013-910-948,12,false,, -073-530-639-749-407,Publication patterns and collaborative dynamics of the fish and wildlife research partnership model,2025-03-31,2025,journal article,Environment Systems and Decisions,21945403; 21945411,Springer Science and Business Media LLC,United States,Sarah Vogel; Cynthia Loftin; Joseph Zydlewski,,45,2,,,Wildlife; Fish ; General partnership; Dynamics (music); Geography; Environmental resource management; Environmental planning; Fishery; Environmental science; Ecology; Sociology; Political science; Biology; Pedagogy; Law,,,,University of Maine; U.S. Geological Survey,,http://dx.doi.org/10.1007/s10669-025-10010-9,,10.1007/s10669-025-10010-9,,,0,000-203-627-584-442; 001-062-477-954-822; 001-096-422-424-600; 001-238-567-414-519; 001-421-046-315-166; 003-868-747-830-164; 004-346-873-594-13X; 004-401-982-629-804; 004-675-932-424-681; 004-682-225-354-448; 006-041-021-332-91X; 007-189-747-098-859; 010-136-645-510-231; 010-593-014-661-424; 013-507-404-965-47X; 015-692-170-714-052; 015-747-077-507-142; 015-833-874-807-51X; 015-991-641-727-432; 016-357-129-875-717; 018-489-917-101-293; 019-380-161-600-179; 021-049-431-196-498; 022-093-898-964-264; 024-288-710-159-793; 024-293-522-010-285; 024-709-266-109-900; 026-754-781-311-922; 027-048-457-606-399; 027-190-600-666-341; 027-845-295-187-970; 028-728-563-956-910; 028-911-721-920-338; 028-990-820-695-461; 029-048-367-824-328; 031-036-766-790-210; 035-100-116-778-77X; 035-494-531-596-791; 037-029-897-660-670; 039-011-133-718-331; 039-825-122-145-235; 040-717-485-874-354; 040-906-180-213-478; 042-216-371-327-739; 047-082-000-016-625; 048-418-481-676-837; 052-528-372-270-08X; 053-067-925-123-547; 056-441-439-197-934; 056-488-921-110-209; 057-791-306-390-972; 058-158-165-981-009; 058-840-051-849-909; 063-601-610-927-161; 069-090-810-480-380; 070-709-829-392-673; 071-583-188-441-759; 072-022-703-824-559; 073-585-726-853-50X; 076-075-938-736-427; 078-444-210-845-528; 079-916-858-123-121; 080-305-994-251-665; 085-509-503-021-74X; 090-283-612-169-104; 098-234-435-889-919; 098-361-545-084-419; 099-374-364-180-638; 099-602-000-994-296; 101-201-232-713-249; 101-848-247-761-283; 102-060-227-040-676; 102-283-458-988-542; 102-365-054-729-682; 103-974-731-754-894; 103-997-670-547-892; 105-402-220-957-576; 106-945-295-200-575; 108-748-550-696-003; 109-207-932-456-544; 111-814-355-110-434; 113-419-893-760-736; 116-563-072-338-912; 117-094-720-234-570; 122-827-252-276-011; 125-107-178-744-297; 126-329-793-053-463; 127-245-926-448-847; 131-394-691-281-280; 132-029-786-454-157; 148-568-289-074-296; 164-369-507-425-903; 166-066-247-998-186; 188-332-136-393-173,0,false,, -073-760-338-998-200,A Bibliometric Analysis: A Tutorial for the Bibliometrix Package in R Using IRT Literature,2022-09-30,2022,journal article,Eğitimde ve Psikolojide Ölçme ve Değerlendirme Dergisi,13096575,Egitimde ve Psikolojide Olcme ve Degerlendirme Dergisi,,Serap BÜYÜKKIDIK,"The bibliometrix package in R programming language, which is frequently used in bibliometric analysis, was introduced in this research. The article aimed to illustrate the various analyses applied in a bibliometric study. For this purpose, articles containing the ""item response theory"" (IRT) or ""item response modeling"" or ""item response model"" terms in the abstract were searched in the Thomson Reuters Clarivate Analytics Web of Science (WoS at http://www.webofknowledge.com), and bibliometric data was downloaded. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) steps were followed in the study. Data from 3388 IRT-related articles on education and psychology, searched between 2001 and 2021, were used in the study. Data were analyzed with the bibliometrix package. Some of the stages in data analysis were shared with screenshots. As a result of data analysis through the real data set, the author’s keywords related to IRT were item response model, differential item functioning, psychometrics, assessment, measurement, reliability, validity, Rasch model, and measurement invariance. The countries with the highest number of citations in IRT studies were the USA, Canada, Netherlands, United Kingdom, and China, respectively. Turkey ranked 12th in IRT studies with 434 citations. It was thought that bibliometric analysis of articles related to IRT would shed light on researchers in the field of psychometrics.",13,3,164,193,Item response theory; Rasch model; Differential item functioning; Psychometrics; Reliability (semiconductor); Item analysis; Classical test theory; Computer science; Bibliometrics; Data science; Psychology; Information retrieval; Statistics; Library science; Mathematics; Clinical psychology; Power (physics); Physics; Quantum mechanics,,,,,https://dergipark.org.tr/en/download/article-file/2237066 https://doi.org/10.21031/epod.1069307 https://dergipark.org.tr/tr/download/article-file/2237066 https://dergipark.org.tr/tr/pub/epod/issue/72844/1069307,http://dx.doi.org/10.21031/epod.1069307,,10.21031/epod.1069307,,,0,002-052-422-936-00X; 009-286-240-384-618; 010-168-316-482-221; 013-507-404-965-47X; 014-914-613-571-578; 016-936-865-870-267; 017-146-468-093-265; 017-300-737-144-757; 017-750-600-412-958; 018-231-132-350-953; 018-653-566-847-158; 024-383-348-891-724; 024-491-347-287-793; 030-849-657-124-093; 032-948-970-548-585; 036-488-025-120-358; 043-568-287-931-453; 046-992-864-415-70X; 054-439-051-844-343; 057-532-630-608-885; 060-110-039-971-60X; 064-400-499-357-900; 079-388-097-137-118; 098-656-027-539-119; 101-026-687-181-95X; 102-991-076-788-892; 105-906-412-980-315; 106-951-303-652-063; 108-625-993-034-260; 137-354-044-881-652,45,true,,gold -073-775-823-470-313,"Bibliometric analysis of ecopreneurship using VOSviewer and RStudio Bibliometrix, 1989–2019",2021-04-30,2021,journal article,Library Hi Tech,07378831,Emerald,United Kingdom,Deepa Guleria; Gurvinder Kaur,"This article offers a bibliometric analysis and explores the relationships among the documents on ecopreneurship by using relational techniques. The results highlight the publication trends; most cited documents, top contributing authors, countries and institutions with highest productivity and most contributing journals to the research field.,Initially, 216 documents were retrieved from the Thompson Reuters Web of Science Core Collection database with three document types: articles, review and book review. All the documents were considered for the analysis. Then VOSviewer and bibliometric analysis using R with an inbuilt utility Biblioshiny were used together for co-word analysis, co-citation network analysis, generating collaboration networks and also generating a unique three-field plot to analyze the evolution of a research field.,The results highlight the publication trends: most cited documents, top contributing authors, countries and institutions with highest productivity and most contributing journals to the research field. The network analysis of co-authorship, co-citation, keyword co-occurrence and bibliographic coupling reveals most prominent relationships between authors, documents, co-cited references, sources and countries for the available documents on the research field.,The study helps not only in expansion of knowledgebase on the research topic but also in understanding the evolution of the ecopreneurship to provide research support further in this area.,Ecopreneurship is an emerging field of research connecting ecology and entrepreneurship together, making it a potential research area. The contributions made to this research field from 1989 to 2019 serve as a core for conducting this analysis. The study is an effort to help in coordinating research network across countries, authors and affiliating universities.",39,4,1001,1024,Sociology; Plot (graphics); Productivity; Data science; Bibliographic coupling; Bibliometric analysis; Network analysis; Field (computer science); Ecology (disciplines); Entrepreneurship,,,,,https://www.emerald.com/insight/content/doi/10.1108/LHT-09-2020-0218/full/html,http://dx.doi.org/10.1108/lht-09-2020-0218,,10.1108/lht-09-2020-0218,3158457682,,0,001-298-695-228-811; 002-052-422-936-00X; 003-485-902-438-19X; 004-620-577-916-930; 005-588-363-310-297; 013-173-326-508-101; 013-646-534-491-567; 014-243-101-580-396; 024-754-973-854-988; 031-141-593-411-693; 037-501-437-329-772; 044-619-564-367-656; 047-134-478-431-993; 055-308-513-495-245; 057-803-697-074-453; 062-302-961-303-805; 065-679-118-952-798; 067-991-076-757-298; 070-659-501-703-981; 072-856-861-900-730; 076-248-332-608-247; 085-870-997-177-134; 088-862-853-155-242; 091-993-059-581-293; 094-248-805-085-865; 100-916-967-962-548; 114-446-925-070-394; 116-339-119-777-116; 143-565-520-194-915; 167-822-565-471-82X,174,false,, -074-032-464-633-625,VALUATION OF BRAZILIAN REAL ESTATE INVESTMENT TRUSTS (REITS) USING THE PSI-COCOSO MULTICRITERIA METHOD,,2025,journal article,Pesquisa Operacional,16785142; 01017438,FapUNIFESP (SciELO),Brazil,Felipe Fortuna Lucas; Marcos dos Santos; Carlos Francisco Simões Gomes,"ABSTRACT In recent years, we have observed growth in the number of investors in the financial market. This work seeks to improve the decision-making process in real estate investment funds (REITs). To this end, a literature review was carried out in the Scopus database using bibliometrix to analyze the applications of the multicriteria decision aid (MCDA) in the environment of Brazilian REITs. The literature review was used as a basis for structuring the problem and the CATWOE analysis was developed to define the alternatives of the application of a hybrid PSI-CoCoSo method for ordering Brazilian REITs in the corporate sector traded on the São Paulo stock exchange (B3). As a result, the hybrid method proved to be effective in the ranking process, providing robust results on the application and evaluation of Brazilian REITs.",45,,,,,,,,,,http://dx.doi.org/10.1590/0101-7438.2025.045.00281684,,10.1590/0101-7438.2025.045.00281684,,,0,002-602-907-955-317; 003-094-039-512-572; 004-046-062-969-394; 005-679-085-165-723; 006-641-868-274-603; 016-278-468-725-38X; 016-992-167-329-509; 018-806-136-639-759; 021-675-241-490-248; 028-764-533-038-56X; 028-897-272-074-819; 032-569-074-069-922; 033-722-639-096-392; 036-604-961-642-146; 042-187-226-837-409; 042-359-151-281-108; 047-823-976-777-245; 049-025-526-460-538; 049-300-815-751-298; 053-720-618-678-824; 057-805-540-841-596; 058-124-722-117-518; 062-591-895-922-678; 071-566-836-814-310; 071-884-103-784-242; 078-560-069-359-499; 081-952-689-466-915; 085-413-903-581-491; 085-899-775-128-416; 088-951-486-768-315; 093-375-393-731-044; 094-125-335-271-013; 094-885-879-338-863; 100-587-156-869-070; 101-554-796-985-382; 101-858-414-222-607; 105-726-486-708-367; 106-480-572-577-657; 114-201-466-315-368; 116-520-510-710-113; 117-391-034-580-44X; 118-321-231-950-81X; 120-841-640-993-256; 123-289-388-604-644; 135-515-386-382-468; 138-526-343-189-986; 149-375-096-044-256; 151-955-153-348-583; 154-917-580-193-856; 157-025-490-216-394; 166-335-606-530-546; 172-709-572-774-251; 173-809-232-490-767; 185-340-025-138-250; 187-854-799-281-895,0,false,, -074-098-591-262-494,Person-centred care in oncological home services: a scoping review of patients' and caregivers' experience and needs.,2025-02-11,2025,journal article,BMC health services research,14726963,Springer Science and Business Media LLC,United Kingdom,Maria Francesca Furmenti; Gaia Bertarelli; Francesca Ferrè,"Cancer became a chronic disease that could be managed at home. Homecare supported person-centred care, which was guided by the Picker Principles defining key elements for care delivery. The study aimed to explore and appraise the dimensions underlying cancer patients' and caregivers' experience and expectations with Home Cancer Care, adopting a person-centerd care framework.; We carried out a scoping review of the literature using three databases, PubMed, Scopus, and WoS for a total of 703 articles. PRISMA guidelines were followed. 57 articles were included in the review. The extracted data were categorized according to the type of care (Palliative, Support, Therapeutic, Recovery after transplant, Rehabilitation), the target population (patients or caregivers), the study design, and the principles related to patients and caregivers' experience, classified through the Picker framework.; The most common type of care in the home setting was palliative care. According to the Picker Principles, most of the studies reported ""Emotional support, empathy and respect,"" followed by ""Clear information, communication, and support for self-care,"" as key consideration for both patients and caregivers. The findings from these studies indicate many positive experiences regarding treatments, services, and interactions with health professionals. Caregivers' needs were most frequently (29%) classified as relational and social. From the patient's perspective, the most common needs fell under the category of ""Health System And Information"" (43%).; We could state that HCCs align with the PCC paradigm; however, careful attention is needed to ensure that the experience of both patients and caregivers remains positive. In our study, a strong need for psychological support does not emerge either for patients or caregivers, unlike previous studies in which psychological needs were among the most frequently cited. Given the growing role of technology in home care, a new category addressing the usefulness and ease of use of technology could be added to the person-centred framework. Recent articles have highlighted the growing use of telemedicine in the home care setting as a support tool for self-care.; © 2025. The Author(s).",25,1,232,,Nursing research; Medicine; Health informatics; Health administration; Nursing; Public health; Health services research; Quality of Life Research; Pain medicine; Health care; Family medicine; Psychiatry; Anesthesiology; Economics; Economic growth,Cancer care; Caregivers; Homecare services; Patient experience; Person centred care,Humans; Caregivers/psychology; Health Services Needs and Demand; Home Care Services/organization & administration; Neoplasms/therapy; Palliative Care; Patient-Centered Care/organization & administration,,,,http://dx.doi.org/10.1186/s12913-024-12058-w,39934798,10.1186/s12913-024-12058-w,,PMC11817070,0,000-598-420-842-941; 000-975-530-378-909; 001-207-957-777-794; 001-800-793-004-054; 003-363-236-796-140; 003-642-534-681-01X; 004-233-838-027-665; 004-544-601-089-807; 004-906-342-059-587; 005-517-908-119-639; 006-784-289-028-537; 008-834-956-323-405; 010-301-226-626-80X; 010-560-071-859-508; 012-274-554-178-382; 012-279-084-480-167; 012-625-209-329-073; 012-802-487-212-574; 012-996-216-354-093; 013-507-404-965-47X; 013-697-075-073-509; 013-874-931-773-079; 015-222-440-115-070; 015-840-780-115-155; 016-430-462-870-766; 016-431-699-064-329; 016-447-158-560-617; 016-468-190-521-469; 016-532-497-799-485; 016-694-698-158-280; 019-318-118-115-584; 020-521-867-024-03X; 020-851-374-866-417; 022-119-310-824-010; 023-671-717-572-148; 026-866-754-581-181; 027-130-378-956-182; 027-242-644-063-560; 029-126-089-937-461; 030-129-086-587-039; 030-832-523-186-255; 031-010-077-149-449; 032-054-734-712-125; 032-331-729-816-184; 032-673-306-444-286; 032-890-115-302-569; 033-439-152-673-350; 034-108-305-678-006; 036-071-445-987-552; 036-984-393-205-817; 037-711-748-062-556; 038-375-772-402-975; 041-130-837-281-098; 045-389-493-027-528; 046-165-381-831-451; 046-667-028-966-574; 046-785-760-417-119; 047-411-417-322-243; 049-354-393-409-858; 050-260-373-436-320; 051-990-022-135-893; 052-322-981-725-859; 053-788-053-012-750; 055-204-345-886-653; 056-256-923-948-950; 057-042-886-030-923; 057-325-390-522-991; 058-220-768-025-870; 058-972-462-306-970; 059-220-356-917-991; 059-222-114-178-443; 062-030-749-361-921; 066-253-376-520-160; 067-633-802-130-175; 070-878-441-671-630; 078-077-234-062-032; 081-629-278-935-828; 081-838-416-673-530; 083-380-881-919-613; 083-704-462-418-257; 084-215-577-562-813; 087-051-307-112-434; 087-364-821-901-329; 093-219-952-542-633; 094-025-594-203-113; 098-945-366-027-784; 100-933-528-377-376; 102-569-781-810-094; 102-701-844-731-541; 105-224-464-369-202; 107-438-500-304-614; 111-808-454-360-147; 112-919-385-783-24X; 117-342-041-359-582; 118-218-956-533-620; 129-263-620-151-866; 135-202-513-195-538; 135-358-242-008-77X; 138-025-749-093-620; 141-132-779-333-842; 161-116-552-067-119; 162-047-242-593-48X; 171-258-226-029-391; 173-550-380-240-276; 176-615-823-381-347; 179-489-745-204-592,2,true,"CC BY, CC0",gold -074-444-849-741-222,Comprehensive Science Mapping Analysis [R package bibliometrix version 3.1.3],2021-05-26,2021,,,,,,Massimo Aria; Corrado Cuccurullo,,,,,,Programming language; R package; Science mapping; Computer science,,,,,,,,,3180379556,,0,,0,false,, -074-611-829-436-39X,Sistemas de Información Geográficos (SIG) basadas en arquitectura WebGIS. Un análisis bibliométrico del estado actual y tendencias de la investigación.,2023-11-17,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Jorge Vinueza Martínez; Mirella Correa-Peralta; Richard Ramirez-Anormaliza; Omar Franco Arias; Daniel Vera Paredes,Este artículo presenta una revisión de la literatura mediante un estudio bibliométrico en el campo de los sistemas de información desde 2002 a 2023. El estudio recopiló 358 publicaciones sobre arquitecturas WebGIS en las últimas dos décadas y utilizó Bibliometrix y Biblioshiny para su análisis.,,,,,Geography; Humanities; Art,,,,,https://zenodo.org/doi/10.5281/zenodo.10149927,http://dx.doi.org/10.5281/zenodo.10149927,,10.5281/zenodo.10149927,,,0,,0,false,, -074-613-605-140-353,Islamic finance and SDGs: bibliometric review and future research agenda,2024-12-26,2024,journal article,Journal of Chinese Economic and Business Studies,14765284; 14765292,Informa UK Limited,United States,Khoutem Ben Jedidia; Mohamed Ghroubi,"This study provides a bibliometric investigation of the relationship between Islamic finance and the Sustainable Development Goals (SDGs), analyzing 457 research articles indexed in Web of Science and Scopus. Using the Bibliometrix package in R and the Biblioshiny interface, the study offers enhanced data visualization and interaction to map the intellectual structure of this field. We highlight a strong alignment between Islamic finance principles (Maqasid al-Shariah) and the SDGs, particularly emphasizing social finance instruments like Zakat and Waqf. In addition, we outline a focus on some SDGs, while others remain underexplored. This study identifies key themes and gaps in the literature and proposes a future research agenda for enhancing Islamic finance's contribution to Sustainable Development Goals.",,,1,34,Waqf; Islam; Sustainable development; Scopus; Islamic finance; Field (mathematics); Political science; Web of science; Accounting; Business; Geography; Archaeology; Mathematics; MEDLINE; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1080/14765284.2024.2445959,,10.1080/14765284.2024.2445959,,,0,000-509-205-864-964; 000-662-574-854-842; 001-416-585-868-812; 002-310-630-722-486; 005-288-118-994-547; 006-632-200-083-466; 007-447-929-392-02X; 007-675-538-494-12X; 007-685-813-636-217; 008-741-036-173-771; 010-680-757-995-578; 011-359-253-738-856; 013-507-404-965-47X; 013-524-854-219-241; 013-651-364-665-785; 014-154-834-798-435; 017-207-639-699-787; 018-222-288-080-406; 020-422-403-863-974; 020-517-414-465-076; 020-632-636-519-627; 024-432-296-135-430; 028-440-162-320-10X; 028-445-907-761-552; 029-420-167-353-195; 033-591-421-049-879; 035-632-251-182-984; 036-868-938-840-100; 038-262-154-799-169; 038-572-603-270-273; 039-082-564-281-301; 040-034-165-828-671; 042-118-660-101-585; 042-425-692-937-15X; 043-238-841-549-621; 045-205-000-236-374; 045-930-541-504-628; 046-774-506-708-195; 049-578-949-411-017; 051-647-739-244-271; 054-065-490-767-577; 054-123-969-008-188; 054-397-575-792-481; 055-273-552-334-543; 057-242-195-606-993; 060-029-415-651-602; 062-426-217-546-168; 065-302-089-334-121; 066-057-927-272-899; 066-319-778-438-476; 069-512-650-195-480; 072-822-195-015-979; 075-189-261-222-801; 075-625-905-735-169; 078-756-630-627-669; 083-001-551-353-773; 084-110-938-370-411; 086-845-963-803-59X; 087-386-979-725-713; 088-934-894-808-14X; 089-567-456-267-755; 091-801-769-246-386; 095-111-415-027-888; 095-911-908-873-172; 098-279-591-295-61X; 101-069-981-884-04X; 101-315-097-306-645; 101-685-616-406-778; 101-752-490-869-458; 103-716-587-942-978; 104-606-754-678-457; 108-203-862-439-663; 109-816-818-906-111; 112-205-856-710-326; 112-388-898-623-727; 112-815-332-304-798; 113-487-669-063-041; 114-197-403-455-794; 115-669-771-832-45X; 119-165-541-690-886; 119-383-110-708-816; 124-928-794-900-638; 125-868-759-995-787; 126-052-855-649-029; 126-817-127-605-441; 128-178-294-207-154; 132-621-301-250-82X; 137-799-175-845-725; 138-983-983-257-434; 141-994-967-705-18X; 143-564-566-159-192; 145-141-917-968-329; 146-031-806-573-374; 147-465-660-240-589; 153-705-196-811-743; 154-012-818-641-06X; 154-175-751-368-99X; 155-213-826-970-581; 156-369-110-454-976; 158-657-014-388-285; 159-670-761-827-387; 163-442-387-567-617; 164-868-316-544-025; 168-942-115-765-364; 179-853-226-008-299; 184-236-957-306-393; 186-560-799-570-005; 189-125-430-487-781; 189-759-747-699-330; 190-748-970-248-382; 196-344-482-144-821; 196-395-105-939-848; 197-481-411-762-187,0,false,, -074-913-548-112-771,Sixty years of research in dental age estimation: a bibliometric study,2023-09-18,2023,journal article,Egyptian Journal of Forensic Sciences,20905939; 2090536x,Springer Science and Business Media LLC,Egypt,Rizky Merdietio Boedi; Scheila Mânica; Ademir Franco,"Abstract; Background; Dental age estimation (DAE) research has grown rapidly and became one of the biggest topics in forensic odontology. This study aimed to evaluate the DAE research trends over the span of 60 years using bibliometric analysis.; ; Methods; Sampling was performed in the Scopus database using a search string (“Dental Age Estimation” OR “Age Determination by Teeth”) to detect DAE-related studies. The search was performed from inception to the year 2022. A data-cleaning intervention using a fuzzy-matching technique was done to unify the author and affiliation name variations.; ; Results; The initial search returned 1638 articles, years of publication ranging from 1964 to 2022, with an approximate growth rate of 5.9% a year. Source analysis showed that most of the top article sources were Forensic Science International (n = 200). Cameriere R presents the overall highest score (77 articles, Local h-index 30). Authors from Shanghai Jiao Tong University produced the highest number of publications (n = 111). The most locally cited study was “A New System of Dental Age Assessment” by Demirjian et al. (Hum Biol 45:211-227, 1973) (n = 1507). The trending topics analysis shows that earlier DAE studies were focused on dental regressive changes and later changed focus to utilizing technological advancements. Institutions and Author's collaborations were also found to be internationally diverse with 20.82% of the articles being a product of international co-authorships.; ; Conclusions; DAE research has grown rapidly helped by multiple advancements in various technological ends. Along with the high demand for DAE analysis, authors and publishers need to continually improve their standards for their respective research and reporting and continue to increase collaboration.; ",13,1,,,Scopus; Forensic odontology; Forensic science; Hum; Library science; Statistics; Dentistry; Medicine; Mathematics; Political science; Computer science; History; MEDLINE; Law; Veterinary medicine; Performance art; Art history,,,,,https://ejfs.springeropen.com/counter/pdf/10.1186/s41935-023-00360-3 https://doi.org/10.1186/s41935-023-00360-3,http://dx.doi.org/10.1186/s41935-023-00360-3,,10.1186/s41935-023-00360-3,,,0,002-120-146-455-374; 002-757-040-487-632; 004-040-792-358-838; 011-558-849-466-435; 013-507-404-965-47X; 013-777-089-965-460; 016-161-652-638-789; 019-060-858-077-784; 022-995-037-775-35X; 032-390-475-600-905; 034-563-302-848-262; 035-275-218-668-461; 038-742-540-661-064; 044-808-566-509-681; 046-992-864-415-70X; 047-253-300-806-008; 053-698-102-089-748; 054-155-485-035-549; 067-194-512-881-315; 070-013-598-429-874; 071-603-231-684-20X; 073-111-752-629-427; 073-732-187-364-99X; 075-646-233-955-750; 080-420-058-886-83X; 080-826-327-971-320; 083-941-303-774-923; 086-588-311-688-86X; 089-334-095-778-850; 099-765-889-708-384; 102-928-826-413-642; 111-277-194-800-192; 119-383-816-422-289; 185-447-009-891-488,4,true,cc-by,gold -075-388-173-703-498,A bibliometric analysis of insurance literacy using bibliometrix an R package,,2022,conference proceedings article,AIP Conference Proceedings,0094243x; 15517616; 19350465,AIP Publishing,,Siti Nurasyikin Shamsuddin; Noriszura Ismail; Nur Firyal Roslan,"Recently, literacy on insurance topics has steadily grown and has gain greater interest among researchers, as shown by the recent increase in publications with an annual growth rate of 8.6%. This study examines the research background of insurance literacy by conducting a comprehensive bibliometric analysis of the insurance literacy topic throughout time, focusing on research trends and the evolution of research interests in this subject. The Scopus database was used as the basis for this research, with the Bibliometrix R package (Biblioshiny) as a software tool with the search query ""literacy"", ""knowledge"", ""proficiency"", ""understand"" and ""insurance"". A total of 386 documents was retrieved and analysed, and the results showed an increased growth rate of literature on insurance lapse from 1953 until 2020. Thus, this article contributes to the field by explicitly providing a detailed overview of the scientific output in insurance literacy and its evolution worldwide. These findings can act as a reference point for future researchers in insurance literacy studies.",2472,,50023,050023,Scopus; Literacy; Computer science; Point (geometry); Subject (documents); Actuarial science; Field (mathematics); Data science; Library science; Political science; Business; Economics; Economic growth; Mathematics; Geometry; MEDLINE; Pure mathematics; Law,,,,,https://aip.scitation.org/doi/pdf/10.1063/5.0092721 https://doi.org/10.1063/5.0092721,http://dx.doi.org/10.1063/5.0092721,,10.1063/5.0092721,,,0,007-757-936-560-822; 013-507-404-965-47X; 016-394-244-104-160; 035-839-837-465-584; 049-391-379-302-694; 058-217-881-275-727; 067-712-114-508-15X; 077-997-287-012-544; 082-869-393-502-808; 090-359-701-014-663; 095-847-118-532-492,3,true,,bronze -075-750-968-769-211,Social Entrepreneurship and Complex Thinking: A Bibliometric Study,2022-10-14,2022,journal article,Sustainability,20711050,MDPI AG,Switzerland,José Carlos Vázquez-Parra; Marco Cruz-Sandoval; Martina Carlos-Arroyo,"This article presents the results of a bibliometric study that aimed to identify academic publications that considered the relationship between social entrepreneurship and the competency of complex thinking and its sub-competencies. The intention is to create a theoretical horizon that provides a complete overview of the current academic correlation between both competencies to identify areas of opportunity for new studies. Methodologically, we reviewed the Scopus and Web of Science databases under the PRISMA protocol. R, RStudio, and Bibliometrix were used to quantitatively analyze the data. The results showed that the number of related publications was minimal and corresponded to current studies, which sheds light on the vast possibilities to analyze the relationship between both variables.",14,20,13187,13187,Scopus; Entrepreneurship; Social entrepreneurship; Knowledge management; Sociology; Social science; Data science; Management science; Computer science; Political science; MEDLINE; Engineering; Law,,,,NOVUS Tecnologico de Monterrey,https://www.mdpi.com/2071-1050/14/20/13187/pdf?version=1665739071 https://doi.org/10.3390/su142013187,http://dx.doi.org/10.3390/su142013187,,10.3390/su142013187,,,0,003-632-305-233-679; 004-802-584-190-012; 013-507-404-965-47X; 017-300-737-144-757; 018-341-462-537-507; 018-559-221-080-181; 023-046-475-886-457; 023-566-898-665-882; 026-152-246-498-184; 028-420-468-321-385; 028-456-403-411-675; 028-835-219-391-539; 035-953-579-141-278; 039-102-332-353-746; 046-992-864-415-70X; 049-391-379-302-694; 065-010-405-236-060; 085-612-945-410-967; 091-931-643-538-426; 096-061-214-240-715; 109-214-920-628-164; 118-231-065-741-174; 125-966-549-211-904; 130-602-202-936-694; 132-801-793-333-653; 139-349-504-211-198; 141-558-987-485-38X; 143-936-693-364-687; 148-074-408-211-979; 148-866-536-481-899; 173-609-563-666-599,29,true,,gold -075-810-822-023-048,55 years of Abacus: Evolution of Research Streams and Future Research Directions,2021-07-08,2021,journal article,Abacus,00013072; 14676281,Wiley,United States,Guilherme Belloque; Martina K. Linnenluecke; Mauricio Marrone; Abhay K. Singh; Rui Xue,"This article offers a systematic literature review and a bibliometric analysis of articles published over the history of the journal Abacus and marks its 55th anniversary. The article draws on the latest available bibliometric tools to provide a citation map, burstiness analysis, and further visualization using R Bibliometrix, highlighting highly cited articles and their interrelations across different research streams, as well as trending (or ‘hot’) topics over the journal's history. We offer reflections on the journal's past and discuss emerging future research directions.",57,3,593,618,Business; Systematic review; Abacus (architecture); Data science; STREAMS,,,,,https://researchers.mq.edu.au/en/publications/55-years-of-iabacusi-evolution-of-research-streams-and-future-res https://onlinelibrary.wiley.com/doi/10.1111/abac.12232,http://dx.doi.org/10.1111/abac.12232,,10.1111/abac.12232,3164590639,,0,003-707-334-476-753; 004-497-453-844-356; 005-030-487-365-676; 005-314-096-647-777; 006-664-514-573-595; 006-716-384-251-943; 007-311-768-770-778; 008-708-576-252-548; 009-116-360-836-736; 009-252-581-665-009; 009-286-240-384-618; 009-324-120-030-289; 009-980-893-123-159; 010-382-848-802-844; 010-639-790-738-499; 011-090-437-185-679; 011-344-196-997-904; 011-424-006-007-587; 011-424-961-504-071; 011-983-878-111-120; 013-507-404-965-47X; 013-524-854-219-241; 014-580-686-450-382; 015-203-306-102-988; 015-575-062-921-350; 016-034-671-512-709; 017-902-602-761-49X; 018-573-865-879-870; 019-404-743-462-371; 021-489-964-224-657; 022-186-780-171-405; 022-374-620-358-017; 023-237-692-405-949; 023-841-019-437-52X; 024-864-833-295-966; 026-779-112-592-967; 027-338-712-549-519; 028-423-562-855-088; 028-838-169-334-731; 028-844-146-856-984; 028-870-300-489-895; 030-431-972-568-980; 031-013-752-451-347; 031-765-346-106-371; 032-599-129-061-168; 032-742-931-204-09X; 033-127-337-483-833; 033-315-208-802-402; 034-738-544-242-919; 035-017-846-135-154; 035-050-845-299-477; 035-085-546-803-549; 035-519-956-380-708; 036-431-557-460-778; 036-701-027-719-866; 037-885-756-397-743; 041-767-529-798-261; 042-993-807-956-146; 043-876-456-419-157; 044-826-302-258-902; 044-864-077-015-003; 046-126-144-007-758; 047-216-652-454-701; 047-833-061-377-904; 050-906-159-723-142; 051-647-739-244-271; 052-237-062-412-740; 052-567-094-068-229; 052-658-825-637-928; 057-347-964-353-910; 057-990-901-185-326; 058-315-135-957-16X; 060-077-252-291-302; 060-328-857-327-551; 060-447-702-126-693; 064-816-151-804-123; 067-003-162-892-510; 068-175-013-123-539; 069-532-514-680-092; 069-727-384-281-076; 069-899-668-932-775; 070-295-530-972-705; 071-618-958-859-607; 074-907-229-061-232; 075-991-251-848-577; 076-057-984-259-861; 078-334-959-283-849; 079-769-950-074-185; 081-007-288-993-099; 082-865-748-615-011; 083-551-630-513-671; 084-425-258-046-390; 085-118-662-187-677; 087-768-136-378-745; 087-795-427-294-465; 088-933-398-055-471; 089-229-463-494-719; 091-619-189-819-722; 092-074-300-993-075; 093-807-163-157-872; 094-344-842-220-691; 094-847-692-060-964; 095-258-654-450-233; 097-657-965-534-937; 098-166-342-015-401; 102-297-539-825-371; 112-660-402-797-775; 113-286-862-532-101; 114-812-069-017-263; 118-971-237-574-012; 121-801-014-665-95X; 124-515-396-811-466; 128-076-820-000-528; 128-944-725-155-334; 129-733-672-715-356; 130-921-362-526-510; 131-596-064-337-359; 132-580-558-479-728; 133-827-866-398-477; 134-940-017-570-106; 138-034-512-500-819; 138-837-675-453-630; 139-476-817-562-935; 147-405-481-722-596; 148-989-316-035-504; 150-743-053-600-568; 151-481-200-257-35X; 152-954-523-302-833; 155-014-318-470-482; 158-132-080-308-667; 160-357-140-463-079; 165-829-288-954-469; 172-488-734-153-129; 177-009-131-837-389; 192-147-609-676-780,14,false,, -076-067-306-691-697,"Performance analysis, conceptual mapping, and emerging trends for Gum Arabic research: a comprehensive bibliometric analysis from 1916 to 2023",2025-01-06,2025,journal article,"Food Production, Processing and Nutrition",26618974,Springer Science and Business Media LLC,,Siddig Ibrahim Abdelwahab; Manal Mohamed Elhassan Taha; Abdalbasit Adam Mariod,"AbstractGum Arabic (GA) is a natural ingredient used in food, pharmaceutical, and cosmetic industries. Numerous studies have been conducted on the physicochemical properties and applications of GA. This study aimed to map knowledge and perform a bibliometric analysis of GA research (GAR) for over a century ago. A search was carried out in the Scopus database using relevant terms and Boolean operators (Gum Arabic OR Acacia gum, OR gum sudani), and data-driven documents in English were extracted. The extracted data included citations, bibliographical and geographical information, abstracts, and keywords. The CVS and BibTex data files were analyzed using VOSviewer and Bibliometrix platforms, respectively. The annual increase in GAR is incremental, consisting of 5313 documents over 108 years and produced by 27 scientific disciplines. The three most productive countries are India, China, and the United States. The rate of international co-authorship was 22.07%, with China being the most collaborative country. Food Hydrocolloids is the most prestigious source. Phillips, G.O., is the most prolific, cited, and co-cited author. Four clusters were detected based on the co-citation analysis of the authors. The most frequent terms in the GAR were “nanoparticles,” “carbon nanotubes,” “stability,” “rats,” “microencapsulation,” and ”lipase.” “Carbon nanotubes” and “microencapsulation” are evolving subjects in GAR. 2000 and 2010 are the turning points in GAR’s thematic evolution. “Ultrasound,” “Pickering emulsion,” “sensory evaluation,” “bioactive compounds,” “cytotoxicity,” and “green synthesis” are the trending topics. Our findings reveal the most common scientific research on GAR, with the physiochemical qualities of GA as a dietary and pharmaceutical constituent being the most common. The marketing, production, tapping, and processing of GA requires further investigation.; Graphical Abstract",7,1,,,Gum arabic; China; Citation; Ingredient; Scopus; Computer science; Chemistry; Food science; Geography; Library science; MEDLINE; Biochemistry; Archaeology,,,,Jazan University,,http://dx.doi.org/10.1186/s43014-024-00276-y,,10.1186/s43014-024-00276-y,,,0,000-384-593-655-833; 000-667-231-896-402; 000-841-437-298-038; 001-061-853-834-193; 001-274-127-714-997; 002-052-422-936-00X; 006-140-224-838-64X; 009-399-306-033-265; 010-081-881-155-192; 010-268-603-377-078; 010-743-006-245-763; 013-716-430-566-203; 013-928-349-839-416; 015-408-703-786-008; 015-715-148-437-879; 016-561-185-336-580; 017-037-873-028-915; 018-876-888-679-095; 021-091-927-191-075; 021-497-315-679-686; 025-657-748-444-503; 026-957-007-084-53X; 036-001-586-242-366; 038-812-642-978-303; 040-532-725-633-103; 046-926-275-834-177; 047-562-308-423-262; 048-475-106-587-841; 049-767-075-163-157; 051-413-364-006-119; 051-493-878-065-258; 056-103-135-975-897; 062-410-900-283-407; 062-593-960-256-544; 067-564-960-479-739; 070-110-682-755-810; 070-654-988-297-459; 075-427-098-343-603; 079-404-287-899-882; 080-686-297-524-877; 085-955-948-570-610; 088-008-250-513-386; 088-058-691-213-755; 090-282-231-648-289; 093-319-503-773-805; 094-460-480-270-189; 097-758-214-762-552; 097-936-505-274-902; 104-651-129-998-837; 107-390-721-593-43X; 109-335-614-340-411; 114-906-498-129-033; 116-692-677-354-043; 117-206-381-775-455; 118-178-091-996-381; 120-744-728-772-55X; 130-998-445-359-768; 131-553-727-979-580; 145-400-703-862-290; 148-555-878-507-413; 172-149-619-340-766; 176-300-221-749-152; 177-360-917-019-773; 177-652-688-005-603; 182-030-806-400-482; 183-406-507-301-985,1,true,cc-by,gold -076-160-360-467-035,Smart city and sustainability indicators: a bibliometric literature review,2024-07-08,2024,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Leonardo da Silva Tomadon; Edivando Vitor do Couto; Walter Timo de Vries; Yara Moretto,"AbstractThis study delves into the pivotal role that indicators play in designing, assessing, and guiding policies for sustainable urban development. Indicators, encompassing both quantitative and qualitative measures, serve as essential tools in evaluating efforts toward sustainable development, providing a practical and objective means of understanding the complex urban environment. The lack of a robust database is identified as a hindrance to monitoring sustainable development progress, underscoring the importance of comprehensive indicators. The study employs a bibliometric literature review methodology, focusing on smart city and sustainability indicators (SSCI) from 2015 to 2022. A total of 818 articles were narrowed down to 191 through rigorous criteria. The study showcases a growing interest in this field, with the number of articles published experiencing a remarkable 288% increase from 2015 to 2022. China emerges as a focal point, leading in both article production and citations, emphasizing its commitment to sustainable development and smart city initiatives. The keywords ""sustainable development"", ""sustainability"" and “urban development” had the most occurrences in text analysis. We found three different clusters with k-means analysis, and the circular economy indicators were the most representative category. In conclusion, the study underscores the holistic vision of SSCI in the current scenario, balancing technology and sustainability to improve urban quality of life while safeguarding the planet. Encouraging further research into integrating resilience-focused indicators and innovative solutions is crucial for enhancing sustainable urban development and informing policy decisions.",5,1,,,Sustainability; Safeguarding; Sustainable development; Environmental planning; Resilience (materials science); Business; Environmental resource management; Regional science; Process management; Political science; Environmental economics; Geography; Economics; Ecology; Biology; Medicine; Physics; Nursing; Law; Thermodynamics,,,,Fundação Araucária; Technische Universität München,https://link.springer.com/content/pdf/10.1007/s43621-024-00328-w.pdf https://doi.org/10.1007/s43621-024-00328-w,http://dx.doi.org/10.1007/s43621-024-00328-w,,10.1007/s43621-024-00328-w,,,0,000-417-615-389-23X; 001-153-564-508-98X; 001-155-022-929-332; 001-323-429-375-458; 001-393-001-635-312; 002-348-252-194-260; 003-098-668-704-321; 003-645-659-638-756; 003-926-395-148-884; 004-159-594-465-163; 004-560-651-012-066; 006-398-329-329-313; 006-661-040-609-221; 007-366-176-751-790; 007-882-837-316-659; 008-057-649-223-179; 008-387-034-379-451; 008-904-480-040-784; 009-925-932-430-898; 010-687-351-838-566; 012-535-340-613-740; 013-357-090-567-477; 013-787-680-635-644; 014-104-102-941-077; 014-536-280-443-985; 014-543-870-913-540; 017-750-600-412-958; 018-233-004-206-323; 019-945-749-449-145; 023-187-488-371-689; 023-367-994-497-274; 024-281-730-991-18X; 024-691-168-890-921; 028-001-644-947-779; 028-054-723-399-052; 029-410-451-794-538; 030-165-096-372-128; 030-310-222-997-435; 030-813-954-936-691; 032-570-364-643-02X; 035-767-555-329-023; 035-811-994-090-398; 035-869-342-873-313; 036-112-860-853-576; 036-775-576-878-351; 037-497-581-627-193; 037-499-025-554-551; 038-436-427-088-395; 040-260-866-359-447; 041-057-403-903-621; 041-137-963-158-64X; 042-029-157-974-472; 045-221-028-040-533; 045-327-521-282-275; 045-344-542-498-731; 045-465-367-752-050; 048-517-451-315-989; 049-429-386-410-58X; 050-409-654-195-925; 050-974-234-753-953; 050-975-884-285-244; 051-087-555-427-257; 052-431-248-374-366; 053-250-767-216-937; 053-442-248-497-905; 056-771-893-296-678; 056-943-403-260-954; 058-601-041-080-536; 058-997-520-413-549; 059-463-108-619-932; 060-778-695-985-858; 061-819-617-379-822; 062-099-640-204-530; 062-800-637-181-860; 062-842-099-137-664; 064-450-623-012-666; 067-380-364-062-682; 067-962-316-822-317; 069-219-051-227-636; 069-733-224-070-73X; 069-784-781-144-367; 071-054-525-662-699; 071-971-096-122-026; 072-207-029-050-010; 072-468-782-770-275; 073-517-271-600-80X; 077-629-167-487-802; 077-812-940-562-01X; 083-045-735-388-297; 083-365-966-950-69X; 084-040-458-286-498; 088-664-267-932-726; 089-553-364-130-252; 089-590-621-611-392; 091-575-430-452-751; 091-807-605-659-165; 091-835-126-068-796; 093-522-894-046-034; 096-203-282-103-561; 096-277-405-488-812; 096-775-731-578-102; 096-922-821-221-948; 098-099-935-679-679; 101-718-691-673-874; 101-884-117-515-998; 105-380-916-549-269; 106-689-368-820-637; 107-991-494-693-783; 108-480-935-933-01X; 114-692-055-292-121; 114-720-421-274-667; 116-353-199-961-079; 117-812-385-205-644; 121-958-932-471-148; 129-769-704-156-697; 131-249-824-613-023; 134-438-008-995-686; 136-504-262-625-854; 140-231-780-414-460; 144-046-008-549-010; 155-406-765-045-392; 158-065-515-628-065; 158-396-042-590-090; 170-878-436-867-554; 173-895-699-623-686; 178-678-071-488-790; 179-647-250-682-948; 184-949-216-026-909; 185-568-972-045-192; 186-448-917-556-07X,7,true,cc-by,gold -076-412-590-067-879,Scoping review and bibliometric analysis of Big Data applications for Medication adherence: an explorative methodological study to enhance consistency in literature.,2020-07-24,2020,journal article,BMC health services research,14726963,Springer Science and Business Media LLC,United Kingdom,Salvatore Pirri; Valentina Lorenzoni; Giuseppe Turchetti,"Medication adherence has been studied in different settings, with different approaches, and applying different methodologies. Nevertheless, our knowledge and efficacy are quite limited in terms of measuring and evaluating all the variables and components that affect the management of medication adherence regimes as a complex phenomenon. The study aim is mapping the state-of-the-art of medication adherence measurement and assessment methods applied in chronic conditions. Specifically, we are interested in what methods and assessment procedures are currently used to tackle medication adherence. We explore whether Big Data techniques are adopted to improve decision-making procedures regarding patients’ adherence, and the possible role of digital technologies in supporting interventions for improving patient adherence and avoiding waste or harm. A scoping literature review and bibliometric analysis were used. Arksey and O’Malley’s framework was adopted to scope the review process, and a bibliometric analysis was applied to observe the evolution of the scientific literature and identify specific characteristics of the related knowledge domain. A total of 533 articles were retrieved from the Scopus academic database and selected for the bibliometric analysis. Sixty-one studies were identified and included in the final analysis. The Morisky medication adherence scale (36%) was the most frequently adopted baseline measurement tool, and cardiovascular/hypertension disease, the most investigated illness (38%). Heterogeneous findings emerged from the types of study design and the statistical methodologies used to assess and compare the results. Our findings reveal a lack of Big Data applications currently deployed to address or measure medication adherence in chronic conditions. Our study proposes a general framework to select the methods, measurements and the corpus of variables in which the treatment regime can be analyzed.",20,1,1,23,Health administration; Health informatics; Psychological intervention; Scientific literature; Nursing research; Scale (social sciences); Medicine; Applied psychology; Big data; Scopus,Bibliometric analysis; Big data; Medication adherence; Scoping review,"Bibliometrics; Big Data; Databases, Factual; Humans; Hypertension/drug therapy; Medication Adherence; Randomized Controlled Trials as Topic",,,https://link.springer.com/content/pdf/10.1186/s12913-020-05544-4.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379348 https://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-020-05544-4 https://www.scilit.net/article/32d2b7c175c4b9ba0b19ca3998b7e859 https://link.springer.com/article/10.1186/s12913-020-05544-4,http://dx.doi.org/10.1186/s12913-020-05544-4,32709237,10.1186/s12913-020-05544-4,3045293577,PMC7379348,0,002-052-422-936-00X; 003-305-113-356-81X; 005-116-452-810-036; 005-350-830-909-865; 005-460-370-362-498; 005-965-560-558-145; 008-417-232-478-236; 011-165-790-731-638; 013-136-074-870-944; 013-303-277-111-046; 013-507-404-965-47X; 015-844-628-624-21X; 016-303-567-431-004; 017-044-842-253-306; 017-300-737-144-757; 019-819-098-483-480; 020-666-158-004-551; 020-741-786-523-712; 021-181-904-851-316; 025-387-551-879-370; 025-554-919-696-448; 025-718-206-028-624; 027-586-570-150-07X; 029-272-183-474-198; 029-361-723-996-021; 032-744-041-956-117; 034-768-039-318-254; 036-717-522-835-49X; 037-036-602-845-527; 039-558-436-414-473; 046-267-534-126-612; 047-356-270-125-579; 055-753-036-187-981; 056-966-071-322-208; 059-502-333-665-846; 059-522-230-513-493; 064-692-006-286-858; 068-454-037-093-436; 070-483-077-816-859; 071-462-846-754-394; 071-878-836-294-733; 074-210-258-142-971; 078-651-223-753-069; 079-283-175-386-590; 080-347-593-500-136; 082-136-265-186-398; 094-465-456-491-259; 100-228-843-189-603; 101-752-490-869-458; 101-819-302-317-845; 102-731-792-552-206; 106-622-749-524-253; 116-179-053-135-048; 117-990-514-100-753; 120-271-131-962-521; 127-245-670-262-773; 129-160-976-363-710; 130-711-103-331-852; 132-723-851-457-646; 134-290-726-004-172; 159-306-125-917-84X; 186-842-017-005-091; 189-884-604-528-836,36,true,"CC BY, CC0",gold -076-532-287-288-325,Changing landscape of fake news research on social media: a bibliometric analysis,2025-01-08,2025,journal article,Quality & Quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Abdelkebir Sahid; Yassine Maleh; Karim Ouazzane,,59,S2,901,954,Misinformation; Social media; Field (mathematics); Citation; Data science; Dissemination; Social network analysis; Fake news; Political science; Internet privacy; Public relations; Sociology; Computer science; World Wide Web; Mathematics; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1007/s11135-024-02048-9,,10.1007/s11135-024-02048-9,,,0,000-761-184-611-339; 002-052-422-936-00X; 003-606-663-686-011; 004-306-474-288-542; 006-828-032-751-924; 007-065-213-823-003; 007-610-728-789-60X; 007-705-093-067-452; 008-549-057-450-926; 008-649-119-278-534; 009-471-726-958-129; 012-096-037-128-767; 013-507-404-965-47X; 013-782-157-265-009; 014-406-644-886-141; 015-264-538-059-64X; 016-197-037-670-933; 017-037-873-028-915; 017-750-600-412-958; 020-238-247-225-160; 022-660-231-334-537; 023-404-925-721-172; 023-771-557-607-994; 023-927-221-065-800; 025-271-384-564-536; 026-149-692-408-217; 027-169-456-712-182; 027-727-877-593-234; 027-891-547-297-963; 028-231-395-101-37X; 028-707-471-465-599; 030-938-434-865-93X; 034-732-911-805-318; 039-107-339-561-313; 044-776-532-451-668; 044-808-566-509-681; 045-422-273-148-899; 045-641-650-728-427; 045-671-919-816-348; 045-797-416-772-535; 045-948-394-509-765; 047-625-572-992-988; 048-916-506-988-602; 050-667-413-498-468; 050-989-847-859-074; 052-534-093-685-398; 053-644-243-097-211; 053-760-242-491-32X; 054-019-477-630-579; 056-790-427-976-901; 056-918-312-788-900; 058-734-352-698-287; 058-989-762-188-102; 060-210-905-439-467; 060-828-803-209-403; 061-510-874-635-473; 062-198-203-703-765; 062-356-601-643-412; 062-847-087-577-948; 064-784-488-619-405; 066-078-460-722-608; 066-177-564-058-012; 066-669-127-338-869; 068-710-228-181-439; 068-970-970-192-264; 069-511-868-544-95X; 069-829-206-257-679; 073-283-790-699-515; 074-475-447-099-128; 075-336-263-231-91X; 075-501-274-677-999; 075-534-362-411-331; 077-785-975-097-508; 078-229-707-084-056; 079-278-714-415-834; 080-534-252-418-613; 081-890-260-533-862; 082-929-659-822-422; 083-233-429-885-517; 085-061-687-762-282; 086-326-264-957-173; 092-545-357-357-975; 095-258-654-450-233; 096-192-064-482-718; 098-101-433-937-308; 098-237-690-955-788; 098-994-150-576-208; 099-754-311-312-208; 099-992-752-455-419; 100-559-203-366-591; 105-389-730-636-293; 105-567-124-922-133; 106-444-260-247-378; 112-762-828-444-018; 113-130-924-711-973; 114-883-530-112-575; 117-528-551-266-488; 120-885-678-404-810; 122-162-869-518-312; 122-827-252-276-011; 125-168-263-761-605; 130-999-386-925-305; 135-034-715-717-613; 135-335-575-875-247; 141-773-984-523-434; 143-065-358-871-285; 144-362-307-811-845; 149-330-237-701-944; 150-774-358-626-525; 151-066-640-236-837; 154-976-048-543-485; 155-113-418-201-099; 163-665-154-946-745; 197-148-988-745-091,1,false,, -076-610-869-908-003,A bibliometric analysis of trust in the field of hospitality and tourism,,2021,journal article,International Journal of Hospitality Management,02784319,Elsevier BV,United Kingdom,Hugo Palácios; Maria Helena Morgani de Almeida; Maria José Sousa,,95,,102944,,Hospitality; Service quality; Sociology; Tourism; Sociology of scientific knowledge; Perspective (graphical); Loyalty; Field (Bourdieu); Bibliometric analysis; Knowledge management,,,,,https://www.sciencedirect.com/science/article/pii/S0278431921000876,http://dx.doi.org/10.1016/j.ijhm.2021.102944,,10.1016/j.ijhm.2021.102944,3157160312,,0,000-207-974-222-807; 001-262-274-011-134; 001-554-466-858-908; 002-052-422-936-00X; 002-193-109-969-736; 004-771-103-585-250; 005-988-112-995-036; 008-736-978-360-515; 008-786-251-643-640; 010-854-534-444-434; 011-488-710-086-357; 013-507-404-965-47X; 013-582-862-145-09X; 015-077-172-307-210; 016-673-730-805-028; 018-182-788-023-746; 022-444-105-615-067; 022-509-785-910-67X; 023-677-748-999-408; 023-876-702-126-822; 027-478-543-241-111; 028-153-066-394-932; 030-550-308-092-429; 033-027-938-206-892; 035-480-473-440-563; 037-574-215-563-501; 038-295-721-107-01X; 038-511-081-070-143; 038-786-731-166-618; 040-172-827-748-300; 041-007-480-439-767; 042-495-131-141-93X; 042-911-354-037-478; 044-763-858-798-124; 046-884-673-288-48X; 048-478-934-614-984; 049-221-301-024-282; 050-979-677-677-438; 052-453-706-214-579; 054-818-565-070-154; 057-058-693-769-402; 057-803-697-074-453; 059-427-364-696-509; 064-662-671-050-039; 065-060-716-384-314; 065-108-368-829-080; 065-486-507-723-023; 069-294-391-974-494; 070-991-991-473-385; 075-526-565-328-087; 077-930-616-453-628; 082-970-012-129-111; 083-098-091-654-893; 083-249-305-167-472; 085-214-676-685-052; 085-280-959-960-574; 089-188-500-609-258; 093-268-736-407-366; 096-868-867-224-947; 097-880-373-519-938; 098-738-660-658-999; 101-201-232-713-249; 102-537-722-712-201; 102-892-733-433-642; 104-413-237-280-28X; 105-482-049-767-205; 107-104-671-850-660; 114-950-692-171-84X; 116-814-998-107-679; 120-040-246-058-26X; 120-974-286-046-262; 122-415-544-444-960; 122-892-829-085-895; 125-718-153-299-302; 128-100-581-455-505; 128-217-524-056-953; 129-341-405-004-303; 130-472-793-008-597; 131-289-614-881-149; 131-798-277-097-622; 132-583-869-382-206; 134-354-192-961-102; 138-674-119-690-463; 139-083-471-253-90X; 141-259-969-446-547; 141-963-954-004-593; 144-967-139-481-948; 145-931-886-075-523; 147-450-929-251-01X; 152-739-356-279-581; 154-163-777-383-030; 155-836-476-011-591; 157-627-782-411-739; 159-306-125-917-84X; 162-245-115-435-371; 163-093-333-625-225; 164-523-589-991-222; 168-867-890-175-157; 170-179-989-648-316; 171-076-077-674-495; 184-708-476-216-541; 195-189-710-734-767,73,false,, -076-642-534-494-386,The Trend of Ganoderma Lucidum Research (1936–2019),2021-08-08,2021,book chapter,Compendium of Plant Genomes,21994781; 2199479x,Springer International Publishing,,Yicen Xu; Jie Yu,"Ganoderma lucidum, as the symbol of traditional Chinese medicine, is one of the most economically important medicinal fungi and has received attention worldwide. The number of scientific research publications about G. lucidum increased rapidly. However, there have been few research reviews concerning the research trend of G. lucidum. Here we used Biblioshiny to analyze 3,286 documents from 1936 to 2019. These documents were screened and analyzed using four software tools: R-package bibliometrix, HisCite, Citespace, and Bibliometric Online Analysis Platform. We presented the performance of relevant sources, authors, institutions, and countries. We analyzed the most highly cited documents of G. lucidum to define the research hotspots and research trends in this field.",,,27,45,Geography; Online analysis; Ganoderma lucidum; Social science,,,,,https://link.springer.com/chapter/10.1007/978-3-030-75710-6_2,http://dx.doi.org/10.1007/978-3-030-75710-6_2,,10.1007/978-3-030-75710-6_2,3187896583,,0,000-623-048-327-047; 003-861-503-301-07X; 006-015-382-212-439; 007-450-082-596-998; 007-483-556-953-514; 007-922-989-316-037; 013-507-404-965-47X; 013-973-241-570-585; 017-598-797-654-577; 021-609-103-915-716; 023-620-543-445-199; 023-841-019-437-52X; 024-250-501-984-793; 024-952-341-137-128; 025-795-316-342-402; 031-738-894-764-873; 034-748-759-191-425; 035-496-656-341-951; 042-633-160-879-768; 043-427-846-491-118; 048-413-455-771-379; 050-151-120-166-593; 051-112-707-365-932; 055-692-814-411-788; 058-941-013-129-356; 059-478-285-286-261; 061-877-295-914-153; 064-304-046-579-981; 067-311-457-380-015; 068-293-203-611-872; 075-931-814-581-008; 086-964-405-104-42X; 087-643-833-438-388; 089-713-073-464-615; 090-376-908-441-982; 091-120-913-247-700; 093-873-147-323-91X; 098-375-225-993-901; 107-994-442-736-239; 108-569-082-832-196; 128-748-632-507-881; 129-353-779-290-752; 131-244-489-577-017; 132-863-223-378-861; 138-561-175-358-392; 145-652-000-305-368; 147-707-161-881-313,2,false,, -077-185-031-966-746,An R Studio Bibliometrix Analysis of Global Research Trends of Educational Crises in 2020s,2024-07-02,2024,journal article,SocioEconomic Challenges,25206621; 25206214,Academic Research and Publishing U.G.,,Artem Artyukhov; Artur Lapidus; Olha Yeremenko; Nadiia Artyukhova; Olena Churikanova,"The article uses R Studio Bibliometrix, VOSviewer, and Connected Papers to structure the scientific work of scientists on the development of educational systems during socio-economic, political, migration, pandemic, and climate crises in the 2020s. The research is based on more than 970 publications (articles, conference abstracts, monographs, and their sections) indexed by Scopus in 2020–2024, selected by keywords: “educational crisis,” “education policy response,” “education disruption,” and “learning loss.” The publication activity grew at an annual rate of 16.45%, peaking in 2023, while the peak of public interest (determined by Google Trends) was in 2022. The study consists of seven parts: the first examines shifts and patterns in the fields of educational crisis; the second analyzes influential publications; the third identifies key research institutions; the fourth explores various counties; the fifth highlights prominent researchers in these fields; the sixth delves into key areas of study; and the seventh uncovers core themes and insights in the research. The study identifies a number of important areas of concentration for the study of educational crises from a thematic perspective. These include education disruption and learning loss, and the broader impact of these issues on inclusive growth and sustainable development. Among all the crises that took place in the world in 2020–2024, COVID-19 and the full-scale war in Ukraine had the greatest impact on the transformation of education systems. China and the United States dominate the world in terms of publication activity and citation of articles by scientists from these countries (their point of view actually determines the emphasis with which the scientific world speaks about challenges in education), while scientists from Australia, India, and the United Kingdom have significantly increased their research activity in this area over the study period. The findings of this study are aimed at understanding the causes and consequences of educational crises and formulating recovery plans to mitigate global risks.",8,2,88,108,Studio; Visual arts; Art,,,,,,http://dx.doi.org/10.61093/sec.8(2).88-108.2024,,10.61093/sec.8(2).88-108.2024,,,0,,3,true,cc-by,gold -077-687-683-996-916,Análisis bibliométrico sobre la producción científica del trabajo social digital con Scopus y bibliometrix,,2021,journal article,Sinergias Educativas,,Grupo Compas,,Darwin Alexis Cruz García; Diana Carolina Tibaná Ríos,"It is presented a systematic review focused on the Working Memory (WM), in this paper had been presented diverse theories, investigations and implications according to the development, disorders and learning process in working memory. The papers revised were obtained from databases between 2015-2020, the result of this research ended in a document that categorizes and classifies the information related with the keywords established. Findings showed that Baddeley and Hicth's multicomponential theory is the most transcendent, however it was not found clear and verifiable information. Besides, the educational field has given the importance of Working Memory in learning, knowing that this process can be affected by stress, or low curricular adaptation to students with special educational needs.",,,,,Scopus; Working memory; Psychology; Field (mathematics); Pedagogy; Humanities; Political science; Cognition; Philosophy; MEDLINE; Mathematics; Pure mathematics; Neuroscience; Law,,,,,https://sinergiaseducativas.mx/index.php/revista/article/download/164/472 https://doi.org/10.37954/se.v6i1.164,http://dx.doi.org/10.37954/se.v6i1.164,,10.37954/se.v6i1.164,,,0,,1,true,cc-by-nc-sa,gold -077-703-907-944-136,MAPEAMENTO BIBLIOMÉTRICO DA RELAÇÃO ENTRE LIBRAS E EDUCAÇÃO: UMA REVISÃO INTEGRATIVA COM BIBLIOMETRIX,,2024,book chapter,COLETÂNEA INTERDISCIPLINAR DOS ESPAÇOS SURDOS,,Even3 Publicações,,Aurenita Émile Sá Miranda; Nícolas Chenquel Nogueira; Layla Rodrigues da Silva.,"A inserção da Língua Brasileira de Sinais (Libras) é importante para o processo de ensino, aprendizagem e inclusão dos Surdos no sistema educacional. No meio acadêmico, as produções intelectuais ressaltam a importância do assunto para a sociedade. Neste trabalho, realizamos uma revisão integrativa de artigos amostrados na SciELO, Scopus e Web of Science com descritores do tema. Nossa pesquisa identificou 227 trabalhos e 533 autores de instituições nacionais e internacionais, entre os anos de 1991 e 2023, apresentando uma média de 23,3 artigos anuais nos últimos cinco anos. Identificamos uma tendência crescente na produção após o ano de 2002. Uma análise dos artigos com maior número de citações na amostra revela discussões sobre a inserção do Surdo nas escolas, conhecimentos acerca de saúde na comunidade, déficit de material didático acessível, entre outros. Nesse contexto, ressaltamos a relevância das produções na desconstrução de estereótipos e preconceitos com a comunidade Surda.",,,73,86,Humanities; Philosophy,,,,,,http://dx.doi.org/10.29327/5433461.2-9,,10.29327/5433461.2-9,,,0,,0,false,, -077-727-317-293-026,Writing in the era of large language models: a bibliometric analysis of research field,2024-12-30,2024,journal article,Research Result. Theoretical and Applied Linguistics,23138912,Belgorod National Research University,,Tatiana A. Litvinova; George K. Mikros; Olga V. Dekhnich,"The widespread adoption of large language models (LLMs) and chatbots over the past two years has significantly altered writing practices. This editorial paper aims to conduct a bibliometric analysis of the interdisciplinary research field concerning various aspects of writing in the context of LLMs. A search was conducted in the bibliographic database Scopus in December 2024 using the following query: (“large language model*” OR “LLM” OR “*GPT”) AND “writing”. We included studies published since 2020 and limited our search to articles, conference proceedings, books and book chapters. The search yielded a total of 1,629 documents. The retrieved records were analyzed using the R package bibliometrix and VOSviewer software. By employing these tools in combination, we identified the most relevant sources, leading countries and institutions, analyzed the most cited publications of the collection and constructed topical clusters. Our findings indicate that the most prominent research topics include the authorship and plagiarism in academic writing, challenges in second language education, automated writing evaluation, and issues related to creative writing in the context of LLMs. Keywords: Large language model; ChatGPT; Writing; Bibliometric review; bibliometrix R-package; VOSviewer; Scopus database; Keyword co-occurrence Acknowledgements: Tatiana A. Litvinova acknowledges the support of the Ministry of Education of the Russian Federation (the research was supported by the Ministry of Education of the Russian Federation within the framework of the state task in the field of science, topic number QRPK-2024-0011). Olga V. Dekhnich and G. Mikros received no financial support for the research, authorship, and publication of this article.",10,4,5,16,Field (mathematics); Bibliometrics; Computer science; Data science; Library science; Mathematics; Pure mathematics,,,,,,http://dx.doi.org/10.18413/2313-8912-2024-10-4-0-1,,10.18413/2313-8912-2024-10-4-0-1,,,0,,0,true,,gold -077-755-743-429-107,"Household energy consumption: state of the art, research gaps, and future prospects",2021-01-03,2021,journal article,"Environment, Development and Sustainability",1387585x; 15732975,Springer Science and Business Media LLC,Netherlands,Xiao Han; Chu Wei,,23,8,12479,12504,Public economics; Primary energy; Energy policy; Consumption (economics); Energy economics; Efficient energy use; Energy poverty; Energy consumption; Energy conservation,,,,National Natural Science Foundation of China; National Statistical Research Program,https://ideas.repec.org/a/spr/endesu/v23y2021i8d10.1007_s10668-020-01179-x.html https://econpapers.repec.org/RePEc:spr:endesu:v:23:y:2021:i:8:d:10.1007_s10668-020-01179-x https://link.springer.com/article/10.1007/s10668-020-01179-x,http://dx.doi.org/10.1007/s10668-020-01179-x,,10.1007/s10668-020-01179-x,3118732103,,0,002-052-422-936-00X; 003-963-038-112-106; 004-832-700-856-174; 005-268-932-591-410; 006-461-237-333-939; 007-285-844-387-054; 008-047-541-440-500; 009-029-718-090-305; 009-799-995-091-200; 010-068-247-756-293; 011-219-712-490-526; 011-759-787-285-751; 012-026-418-160-636; 012-377-320-974-361; 013-028-211-041-301; 013-410-773-037-686; 013-507-404-965-47X; 014-569-792-361-626; 014-757-318-501-319; 015-790-772-806-236; 017-070-283-313-26X; 018-414-938-221-239; 020-124-672-600-210; 020-763-775-882-688; 021-256-689-868-863; 021-279-413-971-204; 023-044-642-447-613; 023-762-254-880-446; 024-471-578-157-437; 026-591-134-281-735; 030-671-248-846-321; 030-726-859-330-661; 032-440-757-687-837; 033-315-971-918-089; 033-663-509-930-951; 034-001-750-006-099; 038-358-692-533-698; 038-398-650-501-31X; 040-125-333-934-806; 040-449-659-091-766; 042-481-532-421-345; 042-796-419-270-430; 043-217-106-229-936; 044-484-644-347-983; 045-993-333-977-461; 047-160-876-791-66X; 050-518-730-636-247; 050-991-252-457-52X; 051-296-267-263-172; 052-016-769-698-747; 054-656-111-759-249; 055-020-799-764-099; 057-440-031-544-789; 061-501-498-342-567; 061-504-138-136-229; 063-336-170-155-158; 064-335-045-358-96X; 064-400-499-357-900; 065-429-139-005-835; 065-793-210-323-299; 067-219-423-011-80X; 068-891-676-152-274; 069-418-264-368-944; 071-661-091-239-66X; 073-766-767-948-145; 074-502-103-504-215; 075-200-067-138-934; 077-081-877-073-507; 077-120-844-940-431; 079-861-125-080-114; 081-308-009-732-451; 082-993-353-800-673; 085-265-568-687-405; 087-371-322-103-010; 088-825-918-091-129; 089-659-211-822-157; 090-013-245-810-296; 093-477-462-533-55X; 096-990-276-764-668; 097-875-158-386-515; 098-040-548-233-718; 098-520-554-125-548; 099-180-772-867-046; 099-887-916-533-512; 101-483-305-132-970; 102-646-054-962-733; 103-931-130-268-970; 104-495-326-573-684; 104-671-335-466-426; 106-831-281-915-70X; 107-670-740-113-629; 109-172-925-539-934; 109-254-666-351-580; 111-460-909-276-810; 112-254-977-335-842; 115-042-891-077-496; 117-516-318-029-824; 117-889-863-500-476; 118-136-207-787-86X; 119-557-426-467-219; 122-048-821-073-618; 122-140-371-564-269; 123-457-102-588-651; 128-129-106-162-85X; 129-927-165-884-345; 137-309-554-094-058; 158-118-149-167-284; 162-337-655-688-036; 163-116-503-914-732; 166-567-305-807-284; 173-478-428-981-716; 183-410-611-755-719,34,false,, -078-333-050-162-039,Emerging Trends and Hot Spots in Epigenetic Modifications in Neurology: A Bibliometric Analysis.,2025-04-11,2025,journal article,Molecular neurobiology,15591182; 08937648,Springer Science and Business Media LLC,United States,Shu-Ying Xu; Siyao Zhang; Chun-Li Zeng; Yong-Jun Peng; Min Xu,"This study employs a bibliometric analysis to examine the evolution and future trajectories in epigenetic modifications in neurology from 2004 to 2024. A total of 12,964 publications were scrutinized via the R bibliometrix package and VOSviewer for network visualization, complemented by Scimagp Graphica to elucidate global collaborative networks. Our extensive review reveals a significant growth in the field of epigenetic neurology studies, driven by an increased output of publications and evidenced by an enhanced focus on epigenetic modifications. The USA and McGill University are recognized as central contributors, with Nature leading as the most prolific journal and J. Mill and E.J. Nestler distinguishing themselves as key authors by publication volume and citation impact, respectively. A detailed keyword analysis highlighted ""expression,"" ""DNA methylation,"" ""brain,"" ""gene-expression,"" and ""gene"" as the most recurrent terms, indicating core areas of research concentration. Subsequent manual analysis due to software-detected inaccuracies reaffirmed Alzheimer's disease, cancer, and schizophrenia as predominant neurological diseases associated with epigenetic studies. Pathophysiological processes such as DNA methylation, oxidative stress, and synaptic plasticity have been extensively examined in relation to epigenetic modifications in neurology. Synthesis of the reference literature analysis identifies critical themes such as the role of glucocorticoid receptors, the significance of hydroxymethylcytosine in neural DNA, the implications of epigenetic patterns in mental health, and the impact of BDNF gene on memory consolidation. Emerging technologies and underexplored areas further highlight future directions. These insights into epigenetic research in neurology indicate a sustained and intensifying trajectory, hinting at expanding horizons for future therapeutic approaches and interventions. Our findings underscore an active and progressing interest in neurological epigenetics, suggesting a continued expansion and specialization in the exploration of epigenetic mechanisms and their clinical relevance.",,,,,Neurology; Epigenetics; Computational biology; Neuroscience; Biology; Genetics; Gene,Bibliometrics; Emerging trends; Epigenetic modifications; Hotspots; Neurology,,,the Applied Basic Research(Medical and Health) Science and Technology Innovation (SYW2024156); Doctoral Research Initiation Fund Project (2024BSJJ04),,http://dx.doi.org/10.1007/s12035-025-04862-0,40216692,10.1007/s12035-025-04862-0,,,0,000-371-754-088-241; 001-108-612-951-503; 001-930-752-700-120; 003-139-567-176-185; 005-538-475-533-182; 006-005-494-483-525; 007-515-834-688-815; 009-470-560-955-520; 011-111-708-296-160; 013-116-284-698-443; 015-087-257-362-082; 016-859-307-269-390; 018-544-015-893-606; 018-901-295-117-902; 021-438-002-002-631; 022-978-276-493-363; 023-827-174-202-607; 024-107-973-596-551; 025-258-076-159-110; 029-007-371-251-226; 029-458-682-606-533; 030-113-292-183-952; 030-848-932-323-042; 031-140-094-350-588; 031-771-179-679-906; 033-478-923-685-045; 033-694-472-150-805; 033-989-507-329-548; 034-046-047-211-233; 040-186-488-123-986; 040-810-180-558-947; 042-878-967-969-225; 043-442-211-175-782; 045-213-195-045-219; 046-430-691-018-073; 049-746-845-989-762; 049-863-263-063-727; 054-082-245-694-938; 055-392-485-534-941; 057-540-476-020-61X; 059-231-070-315-550; 060-793-607-834-706; 064-730-854-557-184; 068-629-560-530-006; 069-923-184-110-465; 078-122-613-950-101; 082-586-271-697-002; 083-309-264-487-219; 094-767-065-284-002; 097-273-496-667-91X; 101-305-936-285-461; 102-867-036-193-554; 103-839-046-571-211; 104-359-738-475-857; 111-183-092-806-684; 123-375-946-352-973; 126-110-280-760-289; 136-290-817-752-750; 155-942-775-917-106; 168-456-247-791-587,0,true,,green -078-368-233-205-759,Defense 4.0 - A Bibliometric Review and Future Research Agenda,2023-04-20,2023,conference proceedings article,Proceedings of the International Conference on Industrial Engineering and Operations Management,,IEOM Society International,,Rafael De Oliveira Vargas; Rodrigo Goyannes; Gusmão Caiado,"This paper presents a bibliometric review of 303 studies on Industry 4.0 (I4.0) in the defense sector obtained from the Web of Science (WoS) platform, published in 227 academic circles, authored by 1211 academics.The objective was to broadly and comprehensively identify the concept of I4.0 within the defense sector and identify future research paths.The documents were analyzed using the Bibliometrix tool in the R software.Based on citation analysis metrics, we revealed the most influential articles, journals, authors and institutions.Using the bibliographic coupling methodology, we identified four research clusters: (1) Additive Manufacturing, 3D printing, spare parts, (2) Internet of Things, Deep Learning, military, (3) Machine Learning, suicide, prediction and (4) Systems, Artificial Intelligence, Expert System.The clusters were analyzed in detail and then a research agenda was proposed.",,,1800,1808,Computer science; Data science; Bibliometrics; Political science; Engineering ethics; Library science; Engineering,,,,,https://ieomsociety.org/proceedings/2022paraguay/349.pdf https://doi.org/10.46254/sa03.20220349,http://dx.doi.org/10.46254/sa03.20220349,,10.46254/sa03.20220349,,,0,,0,true,,bronze -078-425-841-052-563,A bibliometrix-based visualization analysis of international studies on conversations of people with aphasia: Present and prospects.,2023-06-02,2023,journal article,Heliyon,24058440,Elsevier BV,Netherlands,Wei Wei; Zhanhao Jiang,"In recent years, there has been a rapid increase in the number of people with aphasia due to brain lesions worldwide, which has prompted researchers to carry out in-depth studies on the pathogenesis, inducement and prognosis of aphasia from neurology, clinical medicine, psychology and other disciplines. With the deepening of research and understanding of aphasia, it is generally believed that a single discipline can no longer meet the needs of the academic community. Therefore, multidisciplinary integration has emerged and achieved fruitful results. This paper, based on the biblioshiny package run by R, conducts bibliometric analysis on the international interdisciplinary research status of conversation and aphasia, predicts its future development direction, and provides reference for relevant domestic research from international source journals. The results indicate that led by Australia, the United Kingdom, the United States and other countries, the international conversational aphasia research has formed a complete system, and formed a ""descriptive study of patients with language disorders"" and ""applied study of rehabilitation treatment"". In the future, while continuing to focus on these two categories of research, the empathy ability of conversational partners and medical staff may be taken into account, in order to better contribute to improving patients' quality of life.",9,6,e16839,e16839,Aphasia; Visualization; Data science; Psychology; Sociology; Linguistics; Library science; Computer science; Cognitive psychology; Artificial intelligence; Philosophy,Aphasia; Bibliometrix; Biblioshiny; Conversation; Visualized analysis,,,Education Department of Shaanxi Provincial government; Xi'an International Studies University; Xi'an Medical University,https://www.cell.com/article/S240584402304046X/pdf https://doi.org/10.1016/j.heliyon.2023.e16839,http://dx.doi.org/10.1016/j.heliyon.2023.e16839,37346333,10.1016/j.heliyon.2023.e16839,,PMC10279826,0,000-267-535-662-653; 002-052-422-936-00X; 003-275-573-740-308; 003-794-455-974-706; 004-828-734-731-159; 004-889-226-526-211; 005-100-791-007-225; 005-419-807-925-317; 005-470-962-214-500; 005-870-964-156-79X; 007-949-686-088-962; 008-178-239-976-769; 008-677-503-284-902; 008-996-522-647-092; 010-080-490-303-296; 011-277-185-077-881; 011-623-388-069-645; 016-216-132-895-322; 016-765-113-811-877; 017-744-906-724-54X; 018-934-262-729-807; 020-803-334-129-248; 023-133-043-882-175; 026-845-733-807-089; 027-104-299-627-250; 028-545-892-185-860; 028-638-692-195-936; 029-420-167-353-195; 031-275-453-021-531; 036-209-087-418-569; 038-611-254-064-55X; 038-806-732-646-766; 039-657-997-446-479; 040-426-317-702-078; 040-589-303-300-824; 040-692-275-673-45X; 046-992-864-415-70X; 047-134-478-431-993; 047-948-073-890-051; 050-337-879-603-82X; 052-153-810-138-313; 052-548-516-234-028; 052-783-334-540-411; 054-307-538-220-204; 055-956-013-020-927; 059-323-711-990-651; 059-535-661-792-773; 063-421-945-529-175; 064-017-872-250-844; 064-253-351-650-150; 064-398-274-056-808; 070-606-515-653-509; 071-100-483-367-900; 072-345-502-712-370; 074-625-247-745-827; 080-294-980-130-298; 085-005-165-401-010; 089-888-044-787-882; 093-548-866-208-441; 098-022-376-694-163; 101-752-490-869-458; 112-479-518-848-435; 114-304-126-269-889; 115-564-271-693-931; 115-805-431-400-582; 122-754-129-594-706; 125-985-943-558-643; 128-406-277-964-462; 128-651-661-356-591; 144-074-534-990-699; 146-208-436-691-12X; 147-267-762-562-573,30,true,"CC BY, CC BY-NC-ND",gold -078-729-827-219-788,"Caracterización de las relaciones inter-organizacionales: universidad-empresa, stakeholders claves para co-crear valor",2021-06-29,2021,,,,,,Olga Lucia Hurtado Cardona; Iván Alonso Montoya Restrepo; Luz Alexandra Montoya Restrepo,"The purpose of the text is to characterize the relationships presented in the inter-organizational environment University-Industry, as part of a specific objective of an investigation to structure the dimensions and categories of said dyad, in a context where the co-creation of value is encouraged. The methodology is bibliometric analysis using the Bibliometrix R Studio Cloud Package, whose search protocols were performed in the Web of Science (WoS) and Scopus databases. The records were obtained using Gephi and dividing the documents into three categories: hegemonic, structural and recent. The results allowed visualizing four approaches, which are complemented by a study that identified six clusters in 2019, keeping similarity in themes. The conclusions are around the importance of researching the inter-organizational relations University-Industry, as key stakeholders, as they are value co-creators for the society's benefit.",12,1,,,Sociology; Library science; Value (mathematics); Dyad; Similarity (psychology); Context (language use); Bibliometric analysis; Studio; Scopus,,,,,http://revistas.curnvirtual.edu.co/index.php/aglala/article/view/1839,http://revistas.curnvirtual.edu.co/index.php/aglala/article/view/1839,,,3202510533,,0,,0,false,, -078-752-283-803-673,Mapping of global research on familial Mediterranean fever: a SCI-Expanded-based bibliometric analysis.,2022-08-03,2022,journal article,Rheumatology international,1437160x; 01728172,Springer Science and Business Media LLC,Germany,Tauseef Ahmad,,42,12,2231,2239,Familial Mediterranean fever; Medicine; Rheumatology; Bibliometrics; Internal medicine; Family medicine; Disease; Library science; Computer science,Bibliometric analysis; Bibliometrix; Familial Mediterranean fever; SCI-Expanded,Bibliometrics; Familial Mediterranean Fever/genetics; Humans; Publications; Reproducibility of Results; Turkey,,,,http://dx.doi.org/10.1007/s00296-022-05179-0,35920892,10.1007/s00296-022-05179-0,,,0,006-986-479-547-843; 012-883-781-547-890; 015-246-566-795-805; 019-894-779-271-643; 022-669-653-718-320; 023-993-187-299-27X; 024-252-311-645-001; 024-375-917-566-877; 026-250-930-322-416; 026-899-381-699-187; 027-584-546-743-722; 029-086-149-853-582; 033-201-397-994-558; 034-115-585-197-092; 034-768-039-318-254; 035-910-252-804-252; 037-097-537-693-588; 037-356-064-153-226; 039-301-063-832-213; 044-089-369-229-762; 044-565-476-058-545; 053-525-853-300-481; 054-159-894-171-769; 054-366-628-997-658; 076-140-600-881-107; 077-815-180-339-707; 081-632-539-907-33X; 083-518-450-052-420; 086-677-372-730-261; 096-639-706-310-570; 105-051-795-172-372; 107-769-592-371-545; 110-258-151-814-471; 124-885-574-299-601,3,false,, -079-404-287-899-882,"Global trends in research on the effects of climate change on Aedes aegypti: international collaboration has increased, but some critical countries lag behind.",2022-09-29,2022,journal article,Parasites & vectors,17563305,Springer Science and Business Media LLC,United Kingdom,Ana Cláudia Piovezan-Borges; Francisco Valente-Neto; Gustavo Lima Urbieta; Susan G W Laurence; Fabio de Oliveira Roque,"Mosquito-borne diseases (e.g., transmitted by Aedes aegypti) affect almost 700 million people each year and result in the deaths of more than 1 million people annually.; We examined research undertaken during the period 1951-2020 on the effects of temperature and climate change on Ae. aegypti, and also considered research location and between-country collaborations.; The frequency of publications on the effects of climate change on Ae. aegypti increased over the period examined, and this topic received more attention than the effects of temperature alone on this species. The USA, UK, Australia, Brazil, and Argentina were the dominant research hubs, while other countries fell behind with respect to number of scientific publications and/or collaborations. The occurrence of Ae. aegypti and number of related dengue cases in the latter are very high, and climate change scenarios predict changes in the range expansion and/or occurrence of this species in these countries.; We conclude that some of the countries at risk of expanding Ae. aegypti populations have poor research networks that need to be strengthened. A number of mechanisms can be considered for the improvement of international collaboration, representativity and diversity, such as research networks, internationalization programs, and programs that enhance representativity. These types of collaboration are considered important to expand the relevant knowledge of these countries and for the development of management strategies in response to climate change scenarios.; © 2022. The Author(s).",15,1,346,,Aedes aegypti; Climate change; Dengue fever; Geography; Biology; Developing country; Entomology; Socioeconomics; Ecology; Environmental resource management; Sociology; Economics; Larva; Immunology,Bibliometric analysis; International collaboration; Primary dengue virus vector; Temperature effects,Aedes/physiology; Animals; Australia/epidemiology; Brazil/epidemiology; Climate Change; Dengue/epidemiology; Humans; Mosquito Vectors/physiology; Temperature,,,https://parasitesandvectors.biomedcentral.com/counter/pdf/10.1186/s13071-022-05473-7 https://doi.org/10.1186/s13071-022-05473-7,http://dx.doi.org/10.1186/s13071-022-05473-7,36175962,10.1186/s13071-022-05473-7,,PMC9520940,0,002-052-422-936-00X; 003-382-815-347-132; 007-206-645-538-237; 007-285-187-616-645; 009-797-277-577-354; 012-637-284-562-05X; 013-507-404-965-47X; 013-667-445-517-641; 014-259-093-134-156; 017-300-737-144-757; 018-358-569-970-029; 020-750-501-347-722; 021-759-238-793-895; 024-307-493-150-637; 024-429-829-659-847; 026-919-195-272-812; 027-266-550-491-114; 027-321-635-410-722; 027-486-860-528-183; 030-054-278-459-150; 036-752-688-349-17X; 038-720-359-036-021; 042-182-675-032-961; 042-843-899-485-519; 047-931-099-392-21X; 048-300-680-567-912; 049-562-265-373-631; 053-050-186-076-159; 054-350-136-715-320; 060-480-546-341-790; 062-516-983-909-22X; 064-752-658-062-202; 065-622-101-497-357; 071-813-196-158-639; 076-379-034-807-192; 079-889-672-693-379; 093-371-869-415-955; 095-329-860-979-539; 099-326-809-552-240; 099-987-060-522-354; 102-731-144-111-058; 104-122-904-896-222; 106-599-182-961-379; 111-006-478-949-963; 113-426-007-577-765; 120-952-024-839-767; 125-107-178-744-297; 127-696-906-945-347; 131-515-353-223-270; 139-585-736-677-274; 141-562-203-874-638; 142-926-370-624-223; 145-636-347-772-600,26,true,"CC BY, CC0",gold -079-533-234-536-747,A scientometric view of wheat blast: the new catastrophic threat to wheat worldwide,2022-11-30,2022,journal article,Journal of Plant Pathology,22397264; 11254653,Springer Science and Business Media LLC,Italy,Volmir Sergio Marchioro; Giovani Benin; Daniela Meira; Carine Meier; Tiago Olivoto; Luis Antônio Klein; Leomar Guilherme Woyann; Marcos Toebe; Antonio Henrique Bozi,,105,1,121,128,Biology; Plant biochemistry; Biotechnology; Agronomy; Genetics; Gene,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,,http://dx.doi.org/10.1007/s42161-022-01222-y,,10.1007/s42161-022-01222-y,,,0,000-657-058-692-895; 002-052-422-936-00X; 010-463-188-103-582; 011-462-561-165-856; 012-576-765-638-813; 012-877-283-435-000; 013-507-404-965-47X; 017-843-149-656-319; 025-439-817-589-816; 026-675-800-202-022; 032-392-516-305-160; 035-985-184-144-235; 036-797-622-367-550; 038-361-301-170-939; 044-411-896-717-840; 045-963-955-155-617; 047-222-595-703-96X; 049-512-769-140-027; 058-843-034-106-920; 059-408-891-352-616; 059-712-923-961-325; 061-301-899-317-729; 066-633-704-649-583; 071-028-173-322-914; 077-460-173-556-308; 081-218-167-696-039; 083-859-164-821-941; 085-125-959-774-229; 087-890-330-916-534; 101-752-490-869-458; 102-149-538-851-063; 112-880-689-660-067; 115-884-330-231-415; 116-083-022-804-441; 132-730-356-202-713; 141-872-278-038-021; 149-097-273-872-611,2,false,, -079-843-967-891-571,Energy Sales Forecasting in a Sustainable Development Context: Bibliometric Review,,2023,conference proceedings article,strengthening resilience by sustainable economy and business - towards the SDGs,,"University of Maribor, University Press",,Tomasz Zema; Adam Sulich; Lumir Kulhanek,"This paper aims to present different patterns of keyword evolution and their co-occurrences in publications dedicated to energy sales forecasting in a sustainable development context, and indexed in the Scopus and Web of Science Core Collection (WoS) databases. The adopted method is the Structured Literature Review (SLR) variation method with queries supported by the Bibliometrix software as the analytical and visualisation tool. The number of publications has evolved in the context of indexed keywords, which are related. Research on energy sales forecasting and sustainability has earned considerable attention in multiple academic fields. Proposed queries syntaxes and searching procedures in Scopus and Web of Science databases present limitations related to the subscription of these databases and the interchangeability of syntaxes. The novelty of this study is based on the results and their presentation with the usage of Bibliometrix as a tool for the exploration of two independent scientific areas, namely energy sales forecasting and sustainability, and the presentation of connections between them. This paper can inspire researchers to develop the subject of energy sales forecasting evolution in a sustainable development context, as well as business practitioners interested in energy sector adaptation visible in keyword changes in their decision-making processes.",,,99,108,Scopus; Computer science; Sustainability; Context (archaeology); Presentation (obstetrics); Data science; Sustainable development; Bibliometrics; Knowledge management; World Wide Web; Geography; Medicine; Ecology; MEDLINE; Archaeology; Radiology; Political science; Law; Biology,,,,,https://press.um.si/index.php/ump/catalog/view/778/1096/3016-3 https://doi.org/10.18690/um.epf.3.2023.13,http://dx.doi.org/10.18690/um.epf.3.2023.13,,10.18690/um.epf.3.2023.13,,,0,,2,true,cc-by-sa,hybrid -079-887-002-179-54X,Current status and hotspots of in vitro oocyte maturation: a bibliometric study of the past two decades.,2024-09-25,2024,journal article,Journal of assisted reproduction and genetics,15737330; 10580468; 07407769,Springer Science and Business Media LLC,United States,Yi-Ru Chen; Wei-Wei Yin; Yi-Ru Jin; Ping-Ping Lv; Min Jin; Chun Feng,,42,2,459,472,Oocyte; Reproductive medicine; Biology; Human genetics; In vitro fertilisation; Medicine; Pregnancy; Genetics; Embryo; Gene,Bibliometric; Follicle; In vitro maturation (IVM); Oocyte,"Humans; Bibliometrics; In Vitro Oocyte Maturation Techniques/trends; Oocytes/growth & development; Female; Fertilization in Vitro/trends; Reproductive Techniques, Assisted/trends; Animals",,National Natural Science Foundation of China (82171690); Natural Science Foundation of Zhejiang Province (LY22H040002); Natural Science Foundation of Zhejiang Province (LY21H040004),,http://dx.doi.org/10.1007/s10815-024-03272-w,39317914,10.1007/s10815-024-03272-w,,PMC11871283,0,000-098-290-991-728; 000-964-229-453-697; 001-529-615-385-91X; 003-970-982-649-702; 004-158-557-232-710; 004-330-065-623-557; 004-902-310-839-900; 005-014-609-409-957; 005-709-591-696-433; 006-312-058-888-219; 007-144-965-907-934; 009-033-033-336-167; 010-054-907-938-256; 010-881-065-800-574; 012-010-662-851-125; 012-018-710-805-788; 012-179-836-169-649; 013-507-404-965-47X; 014-060-222-744-56X; 014-303-282-162-901; 015-487-083-230-073; 015-847-700-626-126; 016-765-642-763-321; 016-877-194-465-166; 017-131-167-953-67X; 018-486-925-517-252; 020-280-367-256-315; 020-672-204-607-371; 021-472-381-767-501; 021-871-716-610-679; 023-303-316-776-925; 024-903-019-596-392; 025-205-788-892-274; 029-854-942-471-140; 030-124-180-120-854; 031-518-338-836-042; 031-621-897-070-237; 033-030-898-863-528; 033-344-492-809-435; 034-154-858-473-112; 036-349-065-581-503; 036-685-986-102-59X; 036-907-037-822-967; 038-266-122-494-529; 039-907-880-331-351; 040-144-869-412-380; 040-890-104-414-266; 041-430-160-387-046; 041-999-819-275-293; 043-658-707-317-935; 044-197-972-371-630; 045-266-452-601-095; 045-470-099-419-855; 048-299-996-453-377; 048-497-502-857-206; 051-034-000-510-779; 052-361-548-223-761; 053-119-349-225-909; 055-150-114-666-353; 055-358-972-215-05X; 055-915-729-912-305; 057-513-619-911-02X; 058-918-731-444-507; 061-865-522-096-27X; 062-556-737-407-247; 064-097-979-833-049; 067-102-709-279-685; 067-428-746-974-636; 067-813-451-228-178; 069-262-404-932-263; 080-898-367-287-307; 080-959-966-862-349; 082-216-954-437-228; 083-160-156-673-329; 083-986-004-246-863; 085-107-155-705-835; 090-703-259-242-427; 090-777-971-589-223; 093-009-232-540-255; 093-784-375-344-216; 096-633-108-176-634; 098-366-051-244-411; 101-006-591-854-891; 101-227-260-099-114; 104-497-953-316-723; 105-857-911-685-144; 106-827-324-273-531; 107-024-381-131-668; 115-565-610-913-738; 115-595-726-339-261; 116-209-553-275-842; 118-087-426-105-613; 118-092-824-655-633; 120-804-530-256-113; 126-554-437-878-662; 134-626-310-370-407; 134-874-829-621-21X; 135-157-882-462-988; 141-867-997-688-067; 142-973-319-013-680; 152-737-371-186-149; 158-456-418-769-729; 169-485-004-349-355; 194-837-171-440-861,0,false,, -080-168-872-337-649,Top 100 highest cited papers in the field of Scientometrics from 2013 to 2022: A bibliometric analysis,2023-12-31,2023,book chapter,Annual Proceedings of the Science & Technology Metrics,,DLINE,,Ashish Mishra; Govind Yadav; Hariom Mishra; Rajani Mishra,"The present study deals with the bibliometric analysis of the top 100 highest-cited Scientometric papers from the Web of Science (WoS) database during the year 2013 to 2022.The software Bibliometrix and VOSviewer were used for the analysis of the data.We retrieved 885 manuscripts by using the search term ""Scientometric analysis'' and its synonyms then sorted them in ""Highest Cited First'' order in the WoS database.After that, 100 manuscripts were taken as per their citation count for the study.The result reveals that the Year 2020 was the most productive (20 papers) year.The word ""Impact"" was the most frequent word as it occurred 18 times during the period.Among 377 authors, Thelwal M was the most prolific author as he contributed 5 papers and China was the most productive country as it shares 28% of the total papers.LEIDEN UNIVERSITY holds the maximum number of papers, i.e.,44.",,,71,82,Scientometrics; Field (mathematics); Bibliometrics; Library science; Mathematics; Computer science; Pure mathematics,,,,,,http://dx.doi.org/10.6025/stm/2023/4/71-82,,10.6025/stm/2023/4/71-82,,,0,,0,true,,bronze -080-536-035-647-208,Frontline Innovation in Healthcare: Bibliometric analysis (Preprint),2021-07-07,2021,preprint,,,JMIR Publications Inc.,,Kirti Sharma,"; UNSTRUCTURED;

This study evaluates bibliometric analysis of frontline innovation in healthcare domain, depicts emerging themes and provides discussion for further research. Through the use of bibliometrix, the study explores the amount of work published in the field of frontline innovation in healthcare. Specifically, the study identifies whether and to what extent researchers have explored the topic. The result identifies leading trends in terms of main journals, papers, topics, authors, countries and relevant conceptual social networks in the domain in frontline innovation in healthcare.

; ",,,,,Preprint; Health care; Domain (mathematical analysis); Work (physics); Knowledge management; Field (mathematics); Bibliometrics; Social network analysis; Sociology; Data science; Public relations; Political science; Computer science; Library science; Engineering; Social science; World Wide Web; Social capital; Mechanical engineering; Mathematical analysis; Mathematics; Pure mathematics; Law,,,,,,http://dx.doi.org/10.2196/preprints.31848,,10.2196/preprints.31848,,,0,003-258-674-238-988; 005-638-806-940-486; 096-786-974-963-818,0,false,, -080-546-788-830-874,"The state of political science, 2020",2020-10-19,2020,journal article,European Political Science,16804333; 16820983,Springer Science and Business Media LLC,United Kingdom,Magnus Rom Jensen; Jonathon W. Moses,,20,1,14,33,Political science; Pluralism (political theory); State (polity); Citation; Period (music); Social science; Political philosophy; Comparative politics,,,,,https://ntnuopen.ntnu.no/ntnu-xmlui/handle/11250/2824426 https://link.springer.com/article/10.1057/s41304-020-00297-4,http://dx.doi.org/10.1057/s41304-020-00297-4,,10.1057/s41304-020-00297-4,3093865959,,0,002-506-550-449-437; 003-206-880-757-717; 010-396-510-452-928; 013-507-404-965-47X; 023-843-404-656-218; 044-141-221-791-850; 049-247-246-841-065; 066-806-974-652-523; 075-380-444-846-401; 108-587-560-069-340; 126-927-218-398-609; 131-900-393-723-959; 160-769-839-674-233,4,false,, -080-611-857-025-034,A bibliometric analysis of urban greenway literature: implications for interdisciplinary research on urban systems,2024-11-13,2024,journal article,Discover Cities,30048311,Springer Science and Business Media LLC,,Shannon McCarragher; Christopher Acuff; Chapel Cowden; DeAnna E. Beasley,"Greenways serve as an interface between human and natural systems across urban environments, and their use has increased in recent years as a means of providing multimodal transportation options and recreational opportunities in urban settings. Many studies have focused on greenways both in terms of their impact on environmental and health factors, yet studies have generally remained siloed within their respective disciplines. Understanding urban greenways in the context of rapid global change, will require a holistic, interdisciplinary view that considers the entire system to develop integrated knowledge. As such, this paper offers a bibliometric analysis of 267 systematically selected documents on urban greenways for the purpose of identifying knowledge gaps and emerging ideas in the literature. Our findings demonstrate that greenway research is rooted in concepts related to landscape architecture and design and lacks a network across research groups. Disciplines interested in social, political, and economic aspects of the urban system were relatively unexplored in the greenway literature. We see opportunities for interdisciplinary research in areas of environmental justice, urban sustainability, and green infrastructure design. We also encourage more interdisciplinary and practitioner collaborations that can further inform our understanding of ecological and social interactions in the built environment.",1,1,,,Regional science; Geography; Environmental planning; Sociology,,,,,https://link.springer.com/content/pdf/10.1007/s44327-024-00027-1.pdf https://doi.org/10.1007/s44327-024-00027-1,http://dx.doi.org/10.1007/s44327-024-00027-1,,10.1007/s44327-024-00027-1,,,0,000-163-190-899-164; 000-925-165-034-140; 001-784-648-314-446; 007-474-208-367-071; 008-525-976-960-795; 009-432-855-846-623; 011-261-069-296-909; 013-507-404-965-47X; 013-524-854-219-241; 014-397-687-627-738; 015-240-279-246-881; 015-668-341-589-170; 016-915-486-723-598; 017-617-549-358-091; 019-837-175-553-278; 019-842-783-686-564; 020-437-089-180-316; 021-513-845-916-252; 023-011-352-751-739; 023-305-302-983-439; 026-542-718-455-558; 028-178-702-485-52X; 030-804-104-414-833; 032-228-317-639-454; 032-393-127-562-854; 032-795-192-621-154; 033-587-035-493-785; 033-778-663-556-259; 034-768-039-318-254; 034-919-677-302-260; 035-592-503-665-410; 035-833-735-458-44X; 036-550-342-274-208; 040-367-846-228-634; 040-589-303-300-824; 041-145-809-894-139; 042-187-925-343-571; 042-200-807-189-044; 043-293-889-581-358; 043-488-943-825-65X; 044-623-632-272-977; 045-964-221-797-869; 046-992-864-415-70X; 047-593-970-675-140; 050-994-741-311-015; 052-303-844-957-588; 053-331-575-254-765; 054-818-565-070-154; 055-437-960-194-146; 055-489-327-454-066; 056-047-149-278-247; 056-860-509-366-454; 058-944-914-233-488; 059-194-581-692-577; 064-674-585-297-201; 065-038-709-412-662; 069-712-829-785-399; 069-841-017-770-192; 071-002-707-690-91X; 071-613-539-455-349; 072-771-050-304-262; 072-826-802-242-347; 074-889-704-868-582; 077-054-580-208-817; 078-801-375-159-553; 078-919-262-850-093; 078-933-154-848-691; 083-081-164-280-159; 084-637-173-876-867; 086-348-687-013-331; 086-474-206-821-854; 086-481-736-270-549; 092-469-220-298-01X; 096-829-254-558-571; 098-289-202-505-062; 099-134-115-309-856; 102-769-001-590-147; 104-838-603-738-478; 108-117-600-489-432; 112-310-303-221-797; 121-813-144-996-86X; 123-210-280-467-831; 129-591-184-366-571; 137-913-967-206-661; 141-385-622-206-98X; 142-176-540-134-308; 143-849-598-190-089; 155-072-877-630-919; 167-063-466-284-696; 174-135-488-876-979; 180-948-464-512-252; 190-913-924-345-102,1,true,"CC BY, CC BY-NC-ND",gold -080-697-131-989-790,Multi-purpose biorefineries and their social impacts: a systematic literature review,2023-06-27,2023,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Dayvid Souza Santos; Tito Francisco Ianda; Priscila Pereira Suzart de Carvalho; Pedro Luiz Teixeira de Camargo; Fárlei Cosme Gomes dos Santos; Carlos Ariel Cardona Alzate; Fernando Luiz Pellegrini Pessoa; Ricardo de Araújo Kalid,,26,5,10865,10925,Scopus; Context (archaeology); Web of science; Scientific literature; Bibliometrics; Systematic review; Empirical research; Inclusion (mineral); Sustainable development; Business; Social science; Environmental economics; Computer science; Sociology; Economics; Political science; Mathematics; Geography; Library science; Statistics; MEDLINE; Law; Paleontology; Archaeology; Biology,,,,,https://www.researchsquare.com/article/rs-2530661/latest.pdf https://doi.org/10.21203/rs.3.rs-2530661/v1,http://dx.doi.org/10.1007/s10668-023-03445-0,,10.1007/s10668-023-03445-0,,,0,000-658-739-239-708; 001-719-026-803-199; 002-052-422-936-00X; 002-268-973-887-016; 004-840-292-677-600; 005-078-073-366-460; 005-495-254-261-673; 006-703-644-834-414; 006-742-646-418-360; 006-858-169-824-052; 006-967-361-645-241; 007-255-546-591-383; 008-522-954-096-613; 011-301-822-302-672; 013-507-404-965-47X; 013-557-612-260-066; 014-028-204-667-310; 015-445-393-025-782; 015-937-900-640-749; 018-228-372-930-263; 020-038-204-957-189; 020-742-711-607-22X; 021-147-080-842-951; 021-667-684-556-445; 024-291-526-083-28X; 024-347-276-846-503; 025-329-000-722-486; 025-780-539-841-194; 025-998-563-633-979; 031-052-398-443-337; 031-056-855-501-837; 033-294-591-095-025; 034-600-684-728-898; 034-768-039-318-254; 035-496-097-863-314; 036-647-570-894-717; 037-146-191-740-25X; 037-292-191-746-657; 038-417-025-149-833; 039-790-169-943-093; 040-416-373-489-196; 040-714-687-767-684; 042-062-540-885-872; 042-228-490-689-212; 042-863-001-524-955; 045-880-003-478-730; 048-430-555-292-564; 049-581-075-349-247; 050-302-567-036-918; 050-945-349-085-382; 050-999-774-039-233; 051-475-421-341-890; 051-982-515-303-314; 053-366-235-792-663; 054-676-035-109-700; 055-885-558-401-169; 056-435-754-125-411; 056-882-399-956-230; 057-719-200-077-711; 058-575-830-327-179; 059-813-958-364-718; 060-110-039-971-60X; 060-458-839-099-845; 063-064-840-544-915; 063-789-423-782-849; 063-993-989-101-318; 064-331-763-525-402; 064-761-536-125-759; 064-932-852-782-981; 065-458-039-434-109; 066-287-976-353-541; 067-342-140-206-619; 067-925-991-009-108; 072-032-252-768-656; 072-610-861-715-869; 073-227-968-559-709; 073-603-036-054-686; 073-656-023-546-875; 074-773-727-053-832; 076-824-803-447-527; 076-906-522-596-007; 077-598-249-628-673; 077-904-667-132-489; 082-910-592-253-789; 086-519-812-888-844; 089-137-748-754-707; 091-293-037-755-566; 091-414-718-278-337; 091-570-813-289-418; 092-068-089-402-725; 092-351-181-652-800; 093-630-538-727-114; 096-172-869-018-578; 098-009-689-044-333; 100-246-748-353-419; 100-362-423-878-59X; 100-749-831-797-162; 101-065-183-117-606; 101-990-003-080-745; 104-219-899-171-075; 105-314-639-649-951; 105-372-411-923-219; 106-326-759-715-882; 107-206-673-062-403; 108-182-661-418-479; 108-571-798-321-503; 109-779-521-230-739; 111-071-840-759-11X; 113-239-283-444-543; 115-472-167-132-562; 115-817-033-572-213; 116-122-408-694-686; 116-362-801-196-379; 116-518-200-777-803; 119-548-246-437-894; 120-529-529-340-453; 121-776-038-966-229; 121-823-175-446-982; 124-344-461-046-104; 126-219-213-915-200; 128-353-952-787-564; 129-190-856-454-527; 131-204-017-030-543; 134-080-134-499-153; 135-387-521-652-333; 136-583-556-985-01X; 136-877-640-708-094; 143-689-383-266-517; 145-096-015-635-613; 146-037-492-099-696; 149-318-103-625-358; 162-876-824-598-668; 164-609-091-351-305; 167-798-273-969-792; 173-070-922-481-195; 190-992-438-034-059; 197-307-874-253-14X,7,false,, -080-840-276-228-772,DEVELOPMENTS IN INTERNATIONAL BUSINESS MANAGEMENT. A BIBLIOMETRIC ANALYSIS.,2023-04-07,2023,journal article,Russian Law Journal,23137851,Science Research Society,,null ALVARO MENDOZA-CASTILLO et al.,"This paper presents a bibliometric analysis of international business management, developed to know the new trends in the study area and its current situation. The work investigates the evolution of international business management and its contributions to the new global industrial and economic trends. This study focuses on making significant contributions that will provide an appropriate path for opening new research. A meta-analysis is carried out with bibliometrix (software) and the R-Studio statistical package to monitor the most recent trends in this field of study in the scientific articles of the SCOPUS database. Finally, the top results point to a new perspective in international business management. It is possible to highlight four new realities that require greater attention: the growth of populism and economic nationalism, sustainable development and climate change, new digital technologies, and changes in power relations.",11,7s,,,Scopus; Work (physics); Field (mathematics); International business; Regional science; Knowledge management; Management science; Computer science; Political science; Engineering; Management; Sociology; Economics; Mechanical engineering; Mathematics; MEDLINE; Pure mathematics; Law,,,,,https://russianlawjournal.org/index.php/journal/article/download/1442/799 https://doi.org/10.52783/rlj.v11i7s.1442,http://dx.doi.org/10.52783/rlj.v11i7s.1442,,10.52783/rlj.v11i7s.1442,,,0,,0,true,cc-by-nc-nd,hybrid -081-211-330-032-194,Global Research Trend In Digital Learning: Analysis Using Bibliometrix On The Scopus Database,,2024,journal article,Educational Administration: Theory and Practice,,Green Publication,,Syahrul Ramadhan; Sabar Budi Raharjo; Opik Abdurahman Taufik; Wakhid Kozin; Achmad Habibullah; Ahmad Dudin; Elis Lisyawati,"The aims of this article are; a) To analyse the bibliometric keyword ""digital learning"" related to the research performance which consists of annual scientific production, most relevant source, most relevant author, most relevant affiliation, country scientific production and document. 2) To analyse the bibliometric keyword ""digital learning"" related to science mapping which consists of Trend Topic, Co-Accurance Network, Thematic Map, Three-Field Plot, Collaboration Network and Collaboration World Map. This study explores the scientific literature, analysing the performance and trends of digital learning topics using bibliometric. The five stages carried out in this study are keyword determination, data search, article selection, data validation, and data analysis. The researcher then performs this keyword on Scopus database (Scopus.com). The results of the analysis showed that there were 1711 articles collected. Researcher uses R Program to perform the bibliometric analysis.",,,,,Scopus; Thematic map; Computer science; Bibliometrics; Field (mathematics); Data science; Information retrieval; World Wide Web; Geography; Cartography; Political science; Mathematics; MEDLINE; Law; Pure mathematics,,,,,,http://dx.doi.org/10.53555/kuey.v30i4.814,,10.53555/kuey.v30i4.814,,,0,,2,false,, -081-295-948-912-055,Multi-criteria decision-making for equipment selection: A review focused on the triple bottom line,2025-04-07,2025,journal article,Produto & Produção,19838026,Universidade Federal do Rio Grande do Sul,,Vinicius Moretti; Cleiton Hluszko; Diego Alexis Ramos Huarachi; André Luiz De Brito Alves; Rodrigo Salvador; Antonio Carlos De Francisco,"The selection of equipment is a fundamental decision for the business’s future. Several methodologies have been proposed to assist in this kind of decision, one of them being the Multiple Criteria Decision-Making (MCDM) methods. However, over the years, new themes have gained strength such as Environmental, Social, and Governance (ESG), and Circular Economy (CE). This study’s objective is twofold: to identify the main multicriteria methods that are applied in equipment selection, as well as their methods variations and dissemination, and to identify how researchers incorporate sustainability concepts are incorporated in decision-making regarding equipment selection. A systematic review of the literature was conducted using the Methodi Ordinatio to rank the articles. The Bibliometrix tool was used for bibliometric analysis. The results demonstrate no concern with sustainability in the decision-making process in equipment selection. To better integrate MCDM decisions, the authors intend to study a multicriteria model through the sustainable approach.",26,1,21,44,,,,,,,http://dx.doi.org/10.22456/1983-8026.133285,,10.22456/1983-8026.133285,,,0,,0,false,, -081-767-041-754-725,Scientific Mapping Example with R package `bibliometrix`,2023-11-07,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,José Rafael Caro Barrera,Example of the use of the R package bibliometrix for bibliometric analysis,,,,,R package; Computer science; Programming language,,,,,https://zenodo.org/doi/10.5281/zenodo.10079725,http://dx.doi.org/10.5281/zenodo.10079725,,10.5281/zenodo.10079725,,,0,,0,true,cc-by,gold -082-080-566-339-204,Toma de decisiones financieras: perspectivas de investigación,2021-02-23,2021,journal article,Interfaces,00922102; 1526551x,INFORMS Inst.for Operations Res.and the Management Sciences,United States,Damiand Felipe Trejos Salazar; Sindy Lorena Osorio Correa; Leidy Viviana Corrales Marín; Pedro Duque,"La toma de decisiones se relaciona con la personalidad las caracteristicas psicologicas en cada persona hacen que tengan diferentes maneras de ahorrar, esto se da porque se tiene en cuenta el ciclo de vida, el genero, el nivel de educacion o los ingresos. La finalidad de este articulo es realizar una revision detallada sobre el tema. Para lograrlo se realiza un analisis de red con herramientas bibliometricas como Bibliometrix y Gephi, apoyados en las bases de datos WoS y Scopus. Para la clasificacion de los documentos se utilizo la analogia del arbol y se identificaron 3 perspectivas. Se concluye que la observacion y la experiencia afectan los resultados de las decisiones.",4,1,,,,,,,,https://www.unilibrecucuta.edu.co/ojs/index.php/ingenieria/article/download/509/479 http://www.unilibrecucuta.edu.co/ojs/index.php/ingenieria/article/download/509/479,http://www.unilibrecucuta.edu.co/ojs/index.php/ingenieria/article/download/509/479,,,3139539201,,0,,0,false,, -082-723-692-096-334,Sustainable business model innovation literature: a bibliometrics analysis,2022-04-02,2022,journal article,Review of Managerial Science,18636683; 18636691,Springer Science and Business Media LLC,Germany,Ling Pan; Zeshui Xu; Marinko Skare,"Sustainable business model innovation (SBMI) has received growing attention since it can provide sustainable competitive advantages for corporations under a dynamic external environment. This paper aims to understand the current situations and progress of SBMI research by conducting a bibliometric study of the existing literature. By collecting data from Web of Science and using bibliometric tools, the basic characteristics of SBMI research are first presented to show the productivity and citations of publications utilizing recognized bibliometric indicators. Then, the cooperation networks among countries/regions, institutions, and authors are drawn to determine their collaborative relationships. Furthermore, keyword analysis is presented to explore the evolution of the hotspots and themes of SBMI research through co-occurrence analysis, burst detection analysis, and thematic evolution analysis. Finally, we integrate the antecedents-decisions-outcomes framework for SBMI research. The findings in this study indicate that the development of SBMI research is positive and that greater collaboration among institutions and authors is required to explore the internal drivers and design SBMI as well as other topics to be developed.",17,3,757,785,Bibliometrics; Thematic analysis; Scopus; Data science; Knowledge management; Productivity; Computer science; Management science; Business; Sociology; Political science; Social science; Engineering; Economics; Qualitative research; World Wide Web; MEDLINE; Law; Macroeconomics,,,,Innovative Research Group Project of the National Natural Science Foundation of China; Innovative Research Group Project of the National Natural Science Foundation of China,https://link.springer.com/content/pdf/10.1007/s11846-022-00548-2.pdf https://doi.org/10.1007/s11846-022-00548-2,http://dx.doi.org/10.1007/s11846-022-00548-2,,10.1007/s11846-022-00548-2,,,0,002-739-194-363-510; 004-241-101-320-744; 005-975-121-262-560; 009-804-514-833-802; 013-072-218-541-964; 013-507-404-965-47X; 013-772-772-516-480; 016-131-059-057-660; 017-458-705-135-792; 021-384-124-364-998; 022-902-654-665-02X; 023-409-956-595-490; 023-620-543-445-199; 023-822-075-001-17X; 025-111-295-042-100; 026-395-112-558-483; 028-457-565-453-696; 031-578-240-445-97X; 032-766-671-840-212; 038-667-650-012-009; 039-513-977-583-166; 040-995-071-983-26X; 042-192-396-276-591; 044-054-357-242-804; 044-776-532-451-668; 045-247-945-244-15X; 046-584-826-467-936; 046-992-864-415-70X; 049-248-623-852-021; 049-423-095-460-889; 050-937-946-002-725; 053-831-220-519-446; 053-962-979-953-15X; 054-046-934-960-770; 056-540-396-639-061; 057-692-300-493-782; 059-598-901-852-594; 062-678-909-509-983; 063-685-745-177-039; 069-219-051-227-636; 072-969-829-133-480; 074-151-921-136-977; 074-381-777-129-644; 080-735-974-338-157; 083-800-782-247-899; 084-167-367-903-305; 088-068-716-824-659; 088-881-069-223-006; 089-409-767-761-917; 091-733-518-662-930; 097-694-302-731-625; 098-188-966-016-127; 098-648-038-105-666; 100-603-573-401-580; 100-899-672-328-329; 103-578-017-509-360; 105-959-214-219-268; 106-734-069-652-602; 107-573-611-075-561; 108-051-936-108-921; 108-545-579-649-681; 110-478-065-690-761; 111-846-967-780-849; 116-194-587-286-735; 117-409-574-977-600; 143-936-693-364-687; 145-212-135-899-942; 146-663-652-148-070; 162-037-634-091-551; 171-669-629-044-779,50,true,,bronze -083-127-281-936-525,Mining and Extractivism Records Data for Bibliometric Analysis (Scopus database 1992-2020),2021-11-02,2021,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Maika Zampier,The dataset file export from scopus database and the dataset file export as bibliometrix file on excel format from biblioshiny.,,,,,Scopus; Geography; Database; Data science; Political science; Computer science; MEDLINE; Law,,,,,https://zenodo.org/record/5638788,http://dx.doi.org/10.5281/zenodo.5638788,,10.5281/zenodo.5638788,,,0,,0,true,cc-by,gold -083-143-416-382-524,Customer Engagement in Online Brand Communities (OBCs): A bibliometric analysis,2022-03-11,2022,preprint,,,Springer Science and Business Media LLC,,Kunja Sambashiva Rao; Nishad Nawaz; Habeeb Ur Rahiman,"Abstract;

With the advancement in technology and convenience of social media, the customers and marketers' adoption and use of online brand communities have extensively increased. Customer engagement in social media brand communities has become an emerging research topic in the marketing area that has recently brought attention to researchers. The present study conducted bibliometric analysis to evaluate the current level of research has been conducted on the concept of customer engagement in online brand communities. The study has extracted the data from the Scopus database. The study identified 174 relevant research papers, and data was analysed with the help of a bibliometric tool called Bibliometrix. The study has presented significant findings and given some future research directions.

",,,,,Customer engagement; Social media; Scopus; Marketing; Social media marketing; Brand community; Advertising; Business; Sociology; Brand awareness; Political science; Digital marketing; Computer science; World Wide Web; MEDLINE; Law,,,,,https://www.researchsquare.com/article/rs-1380918/latest.pdf https://doi.org/10.21203/rs.3.rs-1380918/v1,http://dx.doi.org/10.21203/rs.3.rs-1380918/v1,,10.21203/rs.3.rs-1380918/v1,,,0,,0,true,cc-by,green -084-196-030-348-695,A Scientometric Analysis of Urban Economic Development: R Bibliometrix Biblioshiny Application,2022-07-03,2022,journal article,Jurnal Ekonomi Pembangunan,27216071; 23029595,Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Lampung,,Nanang Rusliana; Ade Komaludin; Muhamad Ferdy Firmansyah,"This study aims to analyze the development of scientometric research from the theme of urban economic development. The analysis was carried out on 360 articles indexed by Dimension.ai. The method used is scientometric using R Bibliometrix Biblioshiny and VosViewer as processing tools. The results obtained are that this theme has begun to develop significantly in 2020 until now. Research in urban economic development is dominantly published by Chinese authors and affiliates in reputable journals. Research opportunities from urban economic development in emerging themes found the topics of city, innovation, metropolitan, planning, future, and change. This indicates that the potential research themes are in the city planning area which is “innovative”, “future-oriented” and able to “adapt the technology” in “the face of change”. Potential topics in urban economic development were found to have changed from 1964-2013 to 2014-2020 which focused on urban, data, local, contemporary, design and cities. These results can be used as input in compiling research on the theme of urban economic development research and to help researchers find novelty and sustainable impact contributions.",11,2,80,94,Metropolitan area; Theme (computing); Novelty; Urban planning; Regional science; Dimension (graph theory); Geography; Engineering; Computer science; Psychology; Civil engineering; Social psychology; Archaeology; Operating system; Mathematics; Pure mathematics,,,,,http://jurnal.feb.unila.ac.id/index.php/jep/article/download/484/211 https://doi.org/10.23960/jep.v11i2.484,http://dx.doi.org/10.23960/jep.v11i2.484,,10.23960/jep.v11i2.484,,,0,,5,true,,gold -084-208-218-476-360,A bibliometric and knowledge-map analysis of anoikis from 2003 to 2022.,2023-11-24,2023,journal article,Apoptosis : an international journal on programmed cell death,1573675x; 13608185,Springer Science and Business Media LLC,Netherlands,Xueying Hou; Hui Zhang; Enchong Zhang,,29,3-4,457,459,Anoikis; Bibliometrics; Institution; Library science; Apoptosis; Political science; Biology; Computer science; Sociology; Social science; Genetics; Programmed cell death,Anoikis; Apoptosis; Bibliometric; Cancer; Research trends,Humans; Anoikis/genetics; Oncogenes; Bibliometrics; Signal Transduction; Tumor Microenvironment,,Scientific Research Funding Project of Liaoning Provincial Education Department (JCZR2020014); Shenyang Science and Technology Plan (22-321-33-23); 345 Talent Project of Shengjing Hospital of China Medical University (30 Projects),,http://dx.doi.org/10.1007/s10495-023-01910-9,38001344,10.1007/s10495-023-01910-9,,,0,035-600-176-786-174; 046-722-372-785-78X; 047-643-259-001-331; 048-551-803-832-787; 066-892-450-123-624; 093-112-908-629-125; 100-612-118-437-500; 111-861-011-757-359; 123-611-639-423-403,0,false,, -084-372-367-696-513,Research trends on the extracellular domain A/B of fibronectin in tumor microenvironment: scientometric and visual analysis,2025-05-12,2025,journal article,Discover Medicine,30048885,Springer Science and Business Media LLC,,Yuan Zhou; Tao Chen; Yawen Pan; Jing Liu,"Abstract; ; Background; Fibronectin extracellular domain A/B (FN-EDA/B) is a key component of the extracellular matrix (ECM) in the tumor microenvironment (TME). Studies have shown that FN-EDA/B plays multiple roles in tumor development, including promoting tumor cell invasion and metastasis, facilitating immune escape, enhancing tumor angiogenesis, and potentially causing chemoresistance. Despite the substantial volume of published research in this field, a comprehensive perspective is still required to understand the research landscape of FN-EDA/B. Therefore, clarifying the current development status of FN-EDA/B research, identifying its research hotspots, and predicting future trends are crucial for driving scientific progress in this area.; ; ; Methods; We searched for publications spanning from January 2004 to September 2024 and ultimately obtained 322 articles after excluding all unqualified literature. We performed bibliometric and visual analysis using the R packages “Bibliometrix,” “VOSviewer,” and “CiteSpace.”; ; ; Results; The number of FN-EDA/B-related articles has increased annually. The United States is the most productive country in this field, followed by Switzerland, and Italy. ETH Zurich, the Swiss Federal Institutes of Technology, and the International Center for Genetic Engineering and Biotechnology are leading in publication output. Notable authors include Neri, Dario; Chauhan, Anil K; and Jon, Sangyong. Keyword cluster analysis revealed that “angiogenesis,” “precision administration,” “biomarker,” and “targeted FN-EDA/B drug immunotherapy and diagnosis” are hotspots in this research field. “Tumor microenvironment” and “receptors” are identified as frontiers for future research.; ; ; Conclusion; This study provides a comprehensive knowledge framework for the study of FN-EDA/B and offers guidance for clinical researchers to understand the current research status and frontiers in this field.; ",2,1,,,Fibronectin; Tumor microenvironment; Extracellular; Domain (mathematical analysis); Extracellular matrix; Cell biology; Biology; Tumor cells; Cancer research; Mathematics; Mathematical analysis,,,,,,http://dx.doi.org/10.1007/s44337-025-00326-5,,10.1007/s44337-025-00326-5,,,0,002-712-650-725-459; 008-125-284-501-325; 008-171-200-442-848; 008-908-457-868-880; 009-269-294-763-133; 009-556-918-203-479; 010-052-434-406-970; 010-372-026-322-789; 011-663-731-241-809; 011-998-384-906-507; 016-810-775-041-461; 017-978-220-571-771; 018-833-090-832-070; 019-488-281-327-044; 019-965-585-929-545; 020-462-154-388-178; 020-694-179-736-83X; 021-903-295-913-535; 023-527-756-665-009; 024-201-297-207-290; 024-765-592-159-205; 025-770-257-425-839; 026-252-789-153-017; 027-539-916-081-170; 028-209-400-937-622; 029-179-581-366-890; 029-357-087-223-498; 029-445-728-428-638; 030-395-107-458-386; 030-756-104-531-147; 031-220-619-154-580; 031-583-739-073-542; 033-222-052-620-895; 033-875-636-970-168; 035-849-851-004-783; 036-649-625-206-352; 036-871-634-296-06X; 039-963-772-883-112; 042-776-731-312-895; 042-847-392-618-966; 043-361-513-271-513; 044-013-986-654-368; 044-370-922-362-361; 048-065-673-634-278; 048-189-571-378-407; 049-655-016-652-712; 054-102-815-988-555; 056-959-776-814-741; 057-330-943-295-837; 057-780-339-987-181; 060-524-559-112-518; 061-245-430-352-515; 066-356-695-330-921; 067-963-175-310-928; 068-582-947-108-445; 070-499-822-167-876; 072-129-902-994-702; 074-061-186-610-978; 078-519-506-535-864; 079-018-926-003-46X; 081-940-339-211-201; 083-644-041-502-651; 087-903-127-283-874; 090-227-287-916-797; 102-263-042-879-221; 114-771-384-116-423; 117-089-537-347-191; 117-648-105-387-999; 125-408-459-319-800; 132-391-230-795-978; 143-974-719-761-128; 147-209-290-681-199; 149-550-835-263-619; 150-592-396-655-83X; 158-119-833-938-369; 166-790-328-343-226; 170-722-765-792-476; 174-452-530-173-310; 179-787-129-955-785; 197-087-232-024-108; 197-699-483-260-380; 197-938-084-627-021,0,true,cc-by,hybrid -084-387-487-159-060,Top 100 most-cited articles on pelvic organ prolapse: a visualization and bibliometric analysis.,2025-03-28,2025,journal article,Frontiers in surgery,2296875x,Frontiers Media SA,Switzerland,Lu Yang; Qin Tao; Huaye Wu; Litong Yin; Xuemei Wu; Ying Xiong; Xiaoqin Gan; Yonghong Lin; Xia Yu,"Bibliometric analysis is a scientometric method that allows the quantitative analysis of publications. This study used the Web of Science database to perform a bibliometric analysis of the 100 most-cited articles in the field of pelvic organ prolapse (POP) to identify the key research themes and emerging topics within this area.; We collected pertinent publications from the Web of Science Core Collection (WoSCC). The search was conducted using the following keywords: ""pelvic organ prolapse"", ""pelvic organ prolapse"" or ""pelvic organ prolapses"". The search included all publication dates up to June 27, 2024, without any article type restrictions, and the articles were sorted based on their citation count. The top 100 articles with the most citations were included in the subsequent analyses. Several tools, including the Bibliometrix program in R, CiteSpace software, the Online Analysis Platform of Literature Metrology (https://bibliometric.com), and an online interface by Bibliometrix, were used to analyze the data.; The top 100 most cited articles in the field of POP were cited 26,894 times in total. These articles were published between 1993 and 2019, and the majority of them were published during the 10-year period from 2001 to 2010. The United States and the University of California, San Francisco, produced the most publications on this topic. The American Journal of Obstetrics and Gynecology had the greatest influence on POP research. The most prolific author in this field was Barber MD (n = 7). Epidemiological research and treatment, particularly in the area of tissue engineering, were the main focus and current trends in POP research.; This study revealed key research areas and current research hotspots for POP, with a particular focus on epidemiological studies and surgical interventions, especially in the field of tissue engineering. It is suggested that the future research in this field should pay more attention to epidemiological research and treatment, so as to better understand the risk factors of the disease and the characteristics of the affected population, and expect high-quality curative effect and prevention.; © 2025 Yang, Tao, Wu, Yin, Wu, Xiong, Gan, Lin and Yu.",12,,1485426,,Medicine; Visualization; MEDLINE; General surgery; Data mining; Computer science; Political science; Law,CiteSpace; bibliometric; pelvic organ prolapse; research directions; visualization,,,,,http://dx.doi.org/10.3389/fsurg.2025.1485426,40225115,10.3389/fsurg.2025.1485426,,PMC11985531,0,003-875-519-100-974; 007-472-731-552-918; 010-217-061-178-25X; 015-160-182-206-648; 019-250-601-936-587; 022-433-036-257-054; 023-374-201-017-724; 029-214-479-824-200; 029-508-213-257-329; 032-616-164-547-835; 038-593-255-816-489; 040-439-983-432-017; 043-927-818-400-267; 056-134-731-799-30X; 056-508-964-609-910; 062-204-429-475-249; 065-165-342-047-188; 093-089-478-416-601; 097-784-282-441-098; 104-646-253-946-034; 105-644-998-923-926; 108-789-788-426-178; 117-852-338-026-324; 129-741-194-982-635; 130-026-509-847-300; 140-565-311-129-499; 148-998-168-013-032; 162-865-715-427-778; 169-310-298-288-118; 194-494-581-138-671,0,true,cc-by,gold -084-447-695-326-611,A scientometric analysis of technostress in education from 1991 to 2022,2024-05-22,2024,journal article,Education and Information Technologies,13602357; 15737608,Springer Science and Business Media LLC,United Kingdom,Lu Li; Linlin Li; Baichang Zhong; Yuqin Yang,,29,17,23155,23183,Technostress; Educational technology; Psychology; Higher education; Mathematics education; Computer science; Economics; Economic growth; Psychiatry,,,,Natural Science Foundation of Shandong Province,,http://dx.doi.org/10.1007/s10639-024-12781-1,,10.1007/s10639-024-12781-1,,,0,000-467-583-617-052; 000-598-425-169-995; 002-421-742-073-136; 003-240-239-229-192; 004-689-099-057-363; 007-254-442-793-429; 007-505-929-555-055; 008-255-765-535-142; 008-988-932-339-893; 010-718-719-669-190; 010-944-152-334-183; 011-828-214-284-774; 014-173-761-733-377; 017-922-297-064-433; 023-749-708-972-42X; 025-537-243-901-610; 026-703-532-553-12X; 028-596-948-253-034; 030-561-619-442-821; 033-228-106-537-702; 036-881-412-164-626; 040-204-549-274-726; 040-658-267-194-636; 044-176-805-464-802; 049-798-500-757-055; 050-442-114-001-346; 052-882-444-257-805; 056-078-506-331-168; 057-547-458-720-921; 061-852-286-079-589; 063-530-254-881-711; 065-010-405-236-060; 066-714-700-121-997; 067-051-091-642-579; 070-292-669-104-386; 072-169-778-943-962; 075-927-634-289-091; 077-800-316-188-644; 080-686-276-032-590; 086-569-889-493-862; 088-844-926-327-270; 089-308-445-304-331; 089-370-370-337-266; 090-009-664-150-622; 090-553-068-852-555; 102-637-372-638-002; 102-690-748-030-170; 106-182-480-807-27X; 107-518-655-388-824; 109-287-305-694-212; 109-839-542-042-480; 118-496-803-146-080; 120-321-817-402-222; 126-149-422-402-099; 127-273-471-889-846; 134-671-835-288-740; 137-170-500-821-607; 140-830-362-990-566; 153-108-877-433-279; 153-213-675-315-201; 155-323-567-278-298; 160-665-702-252-279; 161-564-790-026-485; 166-187-479-426-778; 168-960-538-371-577; 169-737-411-940-263; 173-986-503-544-550,6,false,, -085-331-709-121-011,Global mismatch of policy and research on drivers of biodiversity loss.,2018-05-21,2018,journal article,Nature ecology & evolution,2397334x,Springer Science and Business Media LLC,England,Tessa Mazor; Christopher Doropoulos; Florian Schwarzmueller; Daniel W. Gladish; Nagalingam Kumaran; Katharina Merkel; Moreno Di Marco; Vesna Gagic,,2,7,1071,1074,Biodiversity; Global biodiversity; Geography; Sustainable development; Extinction; Environmental planning,,"Biodiversity; Conservation of Natural Resources; Extinction, Biological; Policy; Research",,,https://www.ncbi.nlm.nih.gov/pubmed/29784980 https://pubmed.ncbi.nlm.nih.gov/29784980/ https://www.nature.com/articles/s41559-018-0563-x https://espace.library.uq.edu.au/view/UQ:c363b63 https://www.nature.com/articles/s41559-018-0563-x.pdf,http://dx.doi.org/10.1038/s41559-018-0563-x,29784980,10.1038/s41559-018-0563-x,2804274228,,0,006-029-732-647-406; 012-499-312-252-284; 020-610-220-757-448; 028-316-095-498-304; 032-359-927-474-394; 044-698-984-002-491; 050-734-243-012-943; 053-591-063-439-337; 063-264-822-040-939; 068-033-450-354-753; 072-665-414-065-698; 073-480-273-997-699; 077-918-560-780-184; 086-434-561-042-162; 091-422-566-223-926; 100-021-013-635-602; 105-355-667-042-891; 196-906-724-274-584,166,false,, -085-435-304-751-441,Using scientometrics to mapping Latin American research networks in emerging fields: the field networking index,2024-03-21,2024,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Reynaldo Gustavo Rivera; Carlos Orellana Fantoni; Eunice Gálvez; Priscilla Jimenez-Pazmino; Carmen Karina Vaca Ruiz; Arturo Fitz Herbert,,129,4,2309,2335,Scientometrics; Latin Americans; Field (mathematics); Bibliometrics; Index (typography); Computer science; Data science; Library science; Regional science; Political science; Geography; World Wide Web; Mathematics; Pure mathematics; Law,,,,International Society for the Study of Trauma and Dissociation,,http://dx.doi.org/10.1007/s11192-024-04970-z,,10.1007/s11192-024-04970-z,,,0,005-625-606-326-745; 006-041-021-332-91X; 008-185-814-854-06X; 010-556-177-342-193; 013-502-332-163-968; 013-507-404-965-47X; 015-612-897-385-541; 023-666-979-172-148; 031-116-493-149-128; 033-528-851-946-543; 036-421-503-658-472; 037-364-464-123-085; 038-740-037-375-117; 039-629-638-522-857; 043-617-609-965-006; 053-692-261-083-24X; 056-055-845-202-772; 071-904-443-911-979; 078-266-904-646-030; 079-244-464-699-938; 086-569-889-493-862; 087-435-951-893-211; 100-444-109-139-616; 101-054-970-710-923; 105-658-758-342-150; 108-223-726-039-858; 108-686-323-118-093; 119-561-943-926-892; 120-683-413-797-430; 125-107-178-744-297; 132-098-635-378-344; 139-580-627-412-741; 141-364-191-080-365; 146-946-743-395-034; 148-823-572-430-909; 151-336-483-768-908; 154-545-298-576-410; 160-512-654-059-302; 161-658-553-396-738; 165-113-910-842-050; 168-787-440-344-128; 177-027-235-971-995,2,false,, -085-640-667-372-216,Exploring the transformative influence of artificial intelligence in EFL context: A comprehensive bibliometric analysis,2024-08-13,2024,journal article,Education and Information Technologies,13602357; 15737608,Springer Science and Business Media LLC,United Kingdom,Xia Zhang; Kingsley Obiajulu Umeanowai,"This comprehensive bibliometric analysis examines the dynamic impact and influence of artificial intelligence (AI) within the domain of English as a Foreign Language (EFL) from 2013 to 2023. By analysing 3,300 documents from the Web of Science database, the study reveals a positive trend in AI integration, with notable growth attributed to various transformative factors such as the COVID-19 pandemic and increased academic funding. The result analysis identifies leading contributors, top authors, sources, and publishers, revealing China, the United States, and the United Kingdom as influential contributors. The co-occurrence analysis of keywords unveils five clusters representing trends in AI-enhanced language learning, spanning educational technology, EFL teaching factors, learner motivation, and assessment strategies. The study also highlights AI's impact on improving EFL writing skills through tools such as Chatgpt, Grammarly, and Quilbot. However, the study acknowledges limitations in database selection and language constraints. The findings offer valuable insights for researchers, educators, and policymakers, guiding interdisciplinary collaboration and innovative pedagogical approaches.",30,3,3183,3198,Transformative learning; Context (archaeology); Educational technology; Psychology; Computer science; Mathematics education; Sociology; Data science; Pedagogy; Geography; Archaeology,,,,the Higher Education and Teaching Reform Research and Practice Project of Henan Province; Xinyang Agriculture and Forestry University Technology Innovation Team Research Project,,http://dx.doi.org/10.1007/s10639-024-12937-z,,10.1007/s10639-024-12937-z,,,0,001-685-472-901-052; 014-239-954-337-767; 016-150-706-194-308; 017-864-067-241-518; 023-361-728-820-107; 029-205-240-570-785; 031-272-181-919-116; 037-731-223-918-76X; 037-890-133-252-384; 050-218-878-836-726; 060-755-416-696-948; 094-960-719-532-47X; 102-977-826-730-307; 106-475-560-351-718; 106-784-024-575-987; 109-839-305-416-602; 115-957-213-472-601; 145-847-365-315-681; 147-271-606-377-108; 170-742-759-811-173; 176-447-846-258-480; 179-838-915-846-452; 197-874-180-489-001,4,true,cc-by-nc-nd,hybrid -086-082-188-220-525,The evolving role of AI and ML in digital promotion: a systematic review and research agenda,2024-12-12,2024,journal article,Journal of Marketing Analytics,20503318; 20503326,Springer Science and Business Media LLC,,V. G. P. Lakshika; B. T. K. Chathuranga; P. G. S. A. Jayarathne,,13,2,288,307,Scopus; Personalization; Promotion (chess); Context (archaeology); Systematic review; Social media; Computer science; Knowledge management; Data science; Political science; World Wide Web; Paleontology; Biology; MEDLINE; Politics; Law,,,,,,http://dx.doi.org/10.1057/s41270-024-00367-2,,10.1057/s41270-024-00367-2,,,0,000-695-046-602-271; 000-892-930-104-700; 001-719-026-803-199; 003-848-020-591-66X; 004-061-094-888-324; 007-882-224-771-376; 012-849-640-370-762; 013-373-228-196-235; 013-507-404-965-47X; 014-062-675-862-218; 015-846-676-499-58X; 026-081-534-007-989; 026-980-152-189-309; 028-155-036-175-287; 028-574-640-629-237; 029-307-587-709-333; 029-762-777-759-678; 030-795-397-426-683; 032-388-964-516-090; 033-661-157-251-146; 036-774-291-219-059; 041-437-643-724-002; 045-343-422-459-442; 048-318-297-956-101; 049-035-137-428-816; 052-766-968-374-641; 054-130-177-434-416; 054-855-046-600-232; 059-647-821-668-410; 059-805-994-516-643; 061-276-778-368-501; 061-505-985-306-553; 064-481-105-045-021; 064-523-358-666-718; 066-205-482-810-632; 070-355-196-037-528; 074-256-340-899-395; 075-581-661-824-250; 081-671-098-327-779; 086-192-923-822-192; 088-253-355-257-250; 092-600-107-627-61X; 092-620-539-178-756; 093-084-169-278-222; 095-657-169-699-869; 098-806-751-681-678; 104-851-902-147-586; 112-518-971-492-712; 113-682-442-621-962; 116-194-587-286-735; 119-075-943-447-599; 122-981-380-692-525; 123-452-834-073-36X; 124-750-228-956-033; 125-119-044-608-941; 125-976-008-294-590; 126-960-319-979-925; 127-302-568-726-744; 127-768-678-581-747; 128-604-296-387-311; 130-193-974-987-374; 130-899-861-293-637; 133-607-708-233-867; 134-600-515-697-854; 139-555-910-521-375; 140-994-224-220-468; 141-026-656-461-626; 141-211-822-202-49X; 144-818-084-690-822; 146-641-602-872-557; 147-784-139-915-504; 153-220-925-494-501; 165-179-741-253-539; 169-514-714-756-799; 170-198-708-852-809; 172-826-418-148-685; 175-255-288-018-69X; 182-538-987-425-861; 182-867-278-998-779; 188-790-969-065-72X; 195-353-096-775-447; 199-533-480-598-207,3,false,, -086-214-428-132-893,Efficacy of telerehabilitation for total knee arthroplasty: a meta-analysis based on randomized controlled trials combined with a bibliometric study.,2024-12-26,2024,journal article,Journal of orthopaedic surgery and research,1749799x,Springer Science and Business Media LLC,United Kingdom,Xu Liu; Guang Yang; Wenqing Xie; Wenhao Lu; Gaoming Liu; Wenfeng Xiao; Yusheng Li,"Physical therapy (PT) is widely employed in osteoarthritis (OA). This study aimed to explore the research development of PT for OA and to identify the emerging treatment, and verify its efficacy.; The Web of Science Core Collection was used to conduct the bibliometric analysis. Furthermore, a meta-analysis based on randomized controlled trials (RCTs) was performed to evaluate the identified treatment's efficacy.; A total of 3,142 articles were retrieved from the Web of Science Core Collection, and the annual publication volume shows an exponential growth trend (R2 = 0.9515). Keyword analysis demonstrated that telerehabilitation (TELE) in total knee arthroplasty (TKA) has become a hotspot since 2020. To assess the effectiveness of TELE, we conducted a meta-analysis of 25 RCTs including 4402 patients. In the total analysis, the TELE group exhibited superior outcomes compared to the traditional face-to-face (FTF) rehabilitation group in terms of pain (standardized mean differences [SMD]: - 0.15, 95% CI - 0.27 to - 0.04, P = 0.01), passive flexion (MD: 2.60, 95% CI 0.77 to 4.44, P = 0.005), quadriceps muscle strength (SMD: 0.32, 95% CI 0.04 to 0.61, P = 0.03), and cost (SMD: - 0.50, 95% CI - 0.88 to - 0.12, P = 0.009). The subgroup analysis also demonstrated that the fixed equipment-assisted telerehabilitation (FEAT) group and the mobile device-assisted telerehabilitation (MDAT) group were superior to the FTF group. Moreover, patients in the FEAT group exhibited better prognoses than those in the MDAT group. No significant differences in the other measured outcome were observed.; Telerehabilitation proved to be more effective than traditional FTF rehabilitation in patients who underwent TKA. Further research is warranted to compare the different TELE interventions to establish the best protocols and timing for interventions.; © 2024. The Author(s).",19,1,874,,Telerehabilitation; Medicine; Meta-analysis; Randomized controlled trial; Subgroup analysis; Rehabilitation; Physical therapy; Osteoarthritis; Web of science; Orthopedic surgery; Physical medicine and rehabilitation; Telemedicine; Surgery; Internal medicine; Health care; Alternative medicine; Pathology; Economics; Economic growth,Bibliometric analysis; Meta-analysis; Osteoarthritis; Physical therapy; Telerehabilitation,"Humans; Arthroplasty, Replacement, Knee/rehabilitation; Bibliometrics; Osteoarthritis, Knee/surgery; Physical Therapy Modalities; Randomized Controlled Trials as Topic; Telerehabilitation; Treatment Outcome",,"the National Key R&D Program of China (2023YFC3603400, 2023YFB4606705, 2022YFF1100203); National Natural Science Foundation of China (82072506, 82272611, 92268115, 32372349); Natural Science Foundation of Hunan Province (2023JJ30949); Science and Technology Innovation Program of Hunan Province (2023SK2024); Hunan Provincial Science Fund for Distinguished Young Scholars (2024JJ2089); the Independent Exploration and Innovation Project for Postgraduate Students of Central South University (2024ZZTS0276)",,http://dx.doi.org/10.1186/s13018-024-05381-9,39726029,10.1186/s13018-024-05381-9,,PMC11670389,0,000-413-916-096-651; 003-918-735-411-344; 005-927-428-381-816; 006-823-720-585-998; 007-269-813-957-27X; 008-082-121-223-183; 008-286-953-544-03X; 008-995-700-430-108; 011-735-304-525-663; 011-770-732-149-784; 016-186-821-903-987; 018-346-907-602-010; 019-595-767-792-863; 021-686-084-355-731; 023-176-792-416-235; 025-243-658-255-899; 028-570-521-592-701; 028-598-860-395-897; 030-192-797-852-259; 032-161-677-067-644; 032-497-369-187-117; 032-687-387-882-540; 035-044-117-754-418; 035-326-753-039-875; 038-574-374-367-58X; 042-587-830-544-736; 044-700-778-788-438; 046-444-824-250-368; 046-993-438-586-180; 050-341-735-234-49X; 051-857-046-210-023; 054-900-650-503-009; 055-699-193-198-516; 057-490-333-305-64X; 059-883-743-884-592; 064-458-815-244-687; 066-931-423-113-817; 072-799-726-335-785; 073-277-926-615-106; 081-450-696-547-799; 084-391-584-962-48X; 086-583-212-738-451; 087-446-272-458-940; 095-962-464-962-851; 096-523-881-428-512; 097-255-767-590-899; 099-213-479-951-343; 102-195-815-870-287; 106-097-585-358-742; 110-635-551-336-73X; 112-430-248-289-014; 113-573-102-339-650; 114-319-022-285-587; 120-797-612-785-972; 120-852-181-252-62X; 124-896-437-660-134; 150-951-321-824-610; 157-541-075-953-523; 163-286-965-800-598; 185-043-633-813-730,1,true,"CC BY, CC0",gold -086-261-515-354-867,Systematic review and bibliometric analysis of themetabolome found in human breast milk from healthy andgestational diabetes mellitus mothers,2023-12-16,2023,journal article,Revista Nova publicación científica en ciencias biomédicas,24629448; 17942470,Universidad Nacional Abierta y a Distancia,,Sandra Valencia; Martha Zuluaga; Alejandra Franco; Manuela Osorio; Santiago Betancour,"Introduction. Human breast milk is considered the gold standard of nutrition, giventhat thanks to the diversity in the metabolome it manages to meet the individual needs ofeach infant by providing essential metabolites that contribute to and intervene in optimalgrowth and development. Few factors can modify the composition of breast milk and,simultaneously, its benefits. However, the increase in maternal metabolic diseases such asgestational diabetes mellitus raises the question of whether it can be one of the factors thatcondition the quality and quantity of metabolites contained in breast milk. Objective. Toidentify the metabolome of breast milk from healthy mothers, its influence on the growth; and development of the infant, and to recognize those that are altered because of gestatio-nal diabetes mellitus. Methodology. A systematic review was carried out using multiple; databases. For the bibliometric analysis, we used the results of Web of Science and Scopusand the Tree of Science and Bibliometrix software.",21,41,,,Metabolome; Gestational diabetes; Breast milk; Breastfeeding; Diabetes mellitus; Breast feeding; Pregnancy; Medicine; Gold standard (test); Physiology; Metabolomics; Biology; Bioinformatics; Endocrinology; Internal medicine; Pediatrics; Gestation; Biochemistry; Genetics,,,,,https://hemeroteca.unad.edu.co/index.php/nova/article/download/7545/6512 https://doi.org/10.22490/24629448.7545,http://dx.doi.org/10.22490/24629448.7545,,10.22490/24629448.7545,,,0,,0,true,cc-by-nc-nd,gold -086-276-897-077-480,Forefronts and hotspots evolution of the nanomaterial application in anti-tumor immunotherapy: a scientometric analysis.,2024-01-13,2024,journal article,Journal of nanobiotechnology,14773155,Springer Science and Business Media LLC,United Kingdom,Wei Cao; Mengyao Jin; Weiguo Zhou; Kang Yang; Yixian Cheng; Junjie Chen; Guodong Cao; Maoming Xiong; Bo Chen,"Tumor immunotherapy can not only eliminate the primary lesion, but also produce long-term immune memory, effectively inhibiting tumor metastasis and recurrence. However, immunotherapy also showed plenty of limitations in clinical practice. In recent years, the combination of nanomaterials and immunotherapy has brought new light for completely eliminating tumors with its fabulous anti-tumor effects and negligible side effects.; The Core Collection of Web of Science (WOSCC) was used to retrieve and obtain relevant literatures on antitumor nano-immunotherapy since the establishment of the WOSCC. Bibliometrix, VOSviewer, CiteSpace, GraphPad Prism, and Excel were adopted to perform statistical analysis and visualization. The annual output, active institutions, core journals, main authors, keywords, major countries, key documents, and impact factor of the included journals were evaluated.; A total of 443 related studies were enrolled from 2004 to 2022, and the annual growth rate of articles reached an astonishing 16.85%. The leading countries in terms of number of publications were China and the United States. Journal of Controlled Release, Biomaterials, Acta Biomaterialia, Theranostics, Advanced Materials, and ACS Nano were core journals publishing high-quality literature on the latest advances in the field. Articles focused on dendritic cells and drug delivery accounted for a large percentage in this field. Key words such as regulatory T cells, tumor microenvironment, immune checkpoint blockade, drug delivery, photodynamic therapy, photothermal therapy, tumor-associated macrophages were among the hottest themes with high maturity. Dendritic cells, vaccine, and T cells tend to become the popular and emerging research topics in the future.; The combined treatment of nanomaterials and antitumor immunotherapy, namely antitumor nano-immunotherapy has been paid increasing attention. Antitumor nano-immunotherapy is undergoing a transition from simple to complex, from phenotype to mechanism.; © 2024. The Author(s).",22,1,30,,Immunotherapy; Tumor microenvironment; Medicine; Immune system; Cancer research; Immunology,Anti-tumor; Dendritic cells; Drug delivery; Immunotherapy; Nano-immunotherapy; Nanomaterials; Sceintometrics,Biocompatible Materials; Combined Modality Therapy; Drug Delivery Systems; Immunotherapy; Nanostructures,Biocompatible Materials,"the mission book of promotion program of basic and clinical collaborative research of Anhui Medical University (2022xkjT028); the Anhui Provincial Natural Science Foundation (2208085MH240); the Scientific Research Project of Anhui Provincial Department of Education (2022AH051167); the Anhui Quality Engineering Project (2020jyxm0898, 2020jyxm0910, 2021jyxm0727); the Anhui Medical University Clinical Research Project (2020xkj176); the Anhui Health Soft Science Research Project (2020WR01003)",https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-023-02278-3 https://doi.org/10.1186/s12951-023-02278-3,http://dx.doi.org/10.1186/s12951-023-02278-3,38218872,10.1186/s12951-023-02278-3,,PMC10788038,0,002-536-108-330-879; 003-907-450-171-427; 007-521-748-711-012; 010-168-316-482-221; 012-338-619-067-561; 013-507-404-965-47X; 013-524-854-219-241; 015-857-626-727-939; 017-772-893-053-203; 018-614-030-603-655; 019-120-783-639-472; 019-150-462-206-948; 019-168-070-395-706; 024-866-546-606-265; 026-395-112-558-483; 026-752-044-065-064; 027-157-656-939-72X; 027-269-929-577-901; 029-808-665-279-988; 030-159-692-960-865; 032-662-304-241-289; 035-817-719-333-305; 038-831-174-319-051; 039-900-287-022-521; 039-998-002-133-876; 043-908-594-421-929; 044-979-708-035-597; 045-403-661-453-840; 045-783-461-429-480; 048-851-672-324-145; 049-127-833-082-642; 051-143-778-074-122; 053-228-556-883-026; 053-819-428-618-070; 055-199-372-307-553; 055-918-446-317-382; 056-935-521-339-698; 057-803-697-074-453; 065-631-582-911-882; 067-209-435-988-117; 067-886-556-584-002; 069-851-826-021-633; 071-918-484-026-72X; 079-747-261-307-003; 080-596-034-523-339; 084-706-022-991-610; 095-958-799-190-775; 106-884-814-775-914; 107-483-302-885-238; 108-767-612-306-722; 117-196-856-417-322; 127-779-359-843-424; 131-753-539-516-980; 135-412-344-560-033,5,true,"CC BY, CC0",gold -086-478-910-471-825,USE OF BIBLIOMETRIC ANALYSIS AS A TOOL FOR SURVEYING STUDIES ON METABOLOMICS APPLIED TO THE BIOREMEDIATION OF AREAS IMPACTED BY HYDROCARBONS,2023-01-01,2023,dataset,Figshare,,,,Bruna P. da Costa; Camila P. Dantas; Beatriz B. Miranda; Danusia F. Lima; Olívia Maria C. de Oliveira; Karina S. Garcia; Gisele A. B. Canuto; Leonardo S. G. Teixeira,"Bibliometric reviews, carried out from access to databases of scientific articles associated with software for data processing, can be helpful for qualitative and quantitative assessments of existing publications on a given topic. Several petroleum hydrocarbons are carcinogenic and immunotoxic agents, causing adverse effects on the biota, and the study of metabolites generated in bioremediation processes has been the object of current research. Therefore, in this work, the use of bibliometric analysis as a tool for surveying studies on the applied metabolomics bioremediation of areas impacted by hydrocarbons is presented. A bibliometric review was carried out in the Scopus Preview and Web of Science databases with data analysis using RStudio software with the bibliometrix package. The survey gathered the studies and prominent publications of the last seven years, making it possible to present gaps and opportunities in the area.",,,,,Bioremediation; Metabolomics; Environmental science; Earth science; Geology; Biology; Bioinformatics; Ecology; Contamination,,,,,https://scielo.figshare.com/articles/dataset/USE_OF_BIBLIOMETRIC_ANALYSIS_AS_A_TOOL_FOR_SURVEYING_STUDIES_ON_METABOLOMICS_APPLIED_TO_THE_BIOREMEDIATION_OF_AREAS_IMPACTED_BY_HYDROCARBONS/22578334,http://dx.doi.org/10.6084/m9.figshare.22578334,,10.6084/m9.figshare.22578334,,,0,,0,true,cc-by,gold -086-492-054-897-68X,Interdependence and Contagion of Effect in the Agricultural Commodities Market: A Bibliometric Analysis,2023-06-15,2023,preprint,,,MDPI AG,,Thiago Santana; Nicole Rebolo Horta; Mariana Chambino Ramos; Rodrigo Nogueira Vasconcelos; Rui Teixeira Dias; Gilney Figueira Zebende,"The purpose of this article is to conduct a bibliometric review of literary production in terms of market interdependence. We investigate the effect of contagion on agricultural commodities and identify the commodities and methods used in the most cited publications over the decades. For this, we used the SCOPUS database, sorting with Rayyan, Excel, and finally, the Bibliometrix/R-project. The results showed that corn, wheat, soybeans, cotton, and sugar are the most studied commodities. There is no uniqueness concerning the methods used to identify interdependence and the contagion effect. Also, it is possible to perceive the growing scientific interest concerning the subject, with a diversity of authors and magazines. However, there is a direction of the and magazines most cited articles for analyzing agricultural commodities and energy, demonstrated a worldwide trend of studies relating natural resources, biofuels, clean energy, and efficiency. In addition, countries like China and the United States stand out in this scientific scenario as the countries that produce the most articles.",,,,,Agriculture; Scopus; Economics; China; Commodity; Agricultural economics; Geography; Political science; Market economy; Law; Archaeology; MEDLINE,,,,,,http://dx.doi.org/10.20944/preprints202306.1078.v1,,10.20944/preprints202306.1078.v1,,,0,,1,true,,green -086-621-595-657-441,Revisiting sustainable tourism research: bibliometric insights and future research agenda,2024-10-05,2024,journal article,Anatolia,13032917; 21566909,Taylor and Francis Ltd.,United Kingdom,Arslan Rafi; Mohsin Abdur Rehman; Antoine Musu; Raouf Ahmad Rather; Pradeep Kautish,"This bibliometric review synthesizes sustainable tourism research over the past three decades, focusing on its alignment with the Sustainable Development Goals (SDGs). Based on 1,383 journal articles from the Web of Science database, the RStudio Bibliometrix package analysed bibliometric performance, thematic maps, and co-occurrence networks. The findings highlight the role of sustainable tourism in advancing different SDGs. Findings also indicate three broader thematic areas for future research, including regenerative tourism ecosystems, responsible tourism behaviours, and right-sizing tourism. Through this review, we propose future research directions to enhance knowledge on sustainable tourism and its contribution to the SDGs, providing a strategic roadmap for researchers and policymakers.",,,1,16,Tourism; Regional science; Political science; Sustainable tourism; Environmental planning; Sociology; Geography; Law,,,,,,,,,,,0,,0,false,, -086-892-780-153-565,"Research on Sustainable Building Development in the Context of Smart Cities: Based on CiteSpace, VOSviewer, and Bibliometrix",2025-05-25,2025,journal article,Buildings,20755309,MDPI AG,,Bola Chen; Xunrong Ye; Fuping Dai,"Buildings play a pivotal role in the daily functioning of cities, and the development of smart cities is intricately linked to the sustainable development of architectural practices. However, existing reviews have predominantly concentrated on the development of smart cities, often overlooking the interdisciplinary complexities associated with integrating smart city technologies and sustainable building practices. This study systematically reviews 418 relevant papers from the Web of Science database, employing both quantitative and qualitative analytical methods to assess the current status and future trajectory of the field. Therefore, it bridges a significant gap in the existing literature. The findings underscore the contributions of technologies such as the Internet of Things (IoT), artificial intelligence, and big data in enhancing the sustainability of buildings within smart cities. The key areas of focus include energy management, smart building systems, and resource optimisation. Furthermore, the study identifies emerging research themes, such as smart city buildings, smart energy management, and digital twins, highlighting their potential to optimise building performance and foster sustainability within evolving urban systems. The keywords identified in the current body of research are categorised into six main areas: context, objectives, methods, artificial intelligence, emerging technologies, and opportunities and challenges. Research themes are seen to progress from “performance” to “building” and “sustainability” and from “city” to “city” and “sustainability”. Notably, themes such as “city”, “modelling”, and “design” have evolved into themes centred around the “Internet”. However, with the rapid expansion of digital technologies, scholars must also address several critical challenges, including data security and privacy protection, the complexity of cross-system data coordination, uncertainties in sustainable optimisation processes, and the ethical and societal implications of technology adoption. To ensure the successful and sustainable development of future urban smart buildings, it is essential to establish rigorous data security standards, harmonise technical protocols, implement effective global strategies, and prioritise ethical considerations. In addition, unmanned technologies and their associated systems offer valuable insights into the sustainability of buildings in smart cities. Finally, this study presents a comprehensive and systematic framework that provides invaluable insights for future strategic planning and technological advancements in the field.",15,11,1811,1811,Architectural engineering; Context (archaeology); Sustainable development; Engineering; Geography; Political science; Archaeology; Law,,,,,,http://dx.doi.org/10.3390/buildings15111811,,10.3390/buildings15111811,,,0,000-981-869-513-170; 001-323-429-375-458; 002-230-963-654-67X; 002-516-365-880-590; 002-721-519-204-900; 004-082-681-697-437; 004-899-286-207-377; 005-274-542-414-321; 005-827-549-265-514; 009-606-708-042-518; 009-902-284-492-385; 010-039-379-356-969; 010-114-281-002-094; 011-650-353-291-258; 012-185-308-538-528; 012-324-003-378-890; 012-876-332-498-979; 013-507-404-965-47X; 013-640-679-221-480; 015-850-250-340-389; 016-356-316-850-027; 016-604-381-150-166; 016-726-203-017-114; 016-920-535-048-223; 017-823-870-580-331; 017-825-701-594-467; 018-115-075-447-645; 018-981-835-018-263; 019-524-962-683-752; 019-545-045-380-079; 020-652-688-411-691; 023-574-840-949-698; 024-870-026-423-416; 025-063-036-143-376; 025-637-052-093-161; 026-394-133-298-487; 026-529-847-489-635; 027-964-115-458-414; 028-567-201-861-83X; 028-888-305-486-250; 029-032-368-926-602; 029-382-621-621-66X; 029-384-328-280-287; 029-410-451-794-538; 029-998-496-516-179; 030-791-317-205-074; 031-341-058-300-875; 031-513-328-457-070; 031-630-961-713-175; 032-761-633-537-850; 034-338-733-740-375; 034-936-809-982-080; 036-025-088-904-167; 036-862-556-793-460; 037-116-924-952-333; 039-019-946-746-133; 039-829-296-373-56X; 041-122-934-788-739; 042-291-468-344-324; 043-167-736-103-913; 046-992-864-415-70X; 047-059-947-830-966; 048-814-864-231-469; 048-975-544-776-280; 049-541-957-747-355; 053-198-425-721-954; 053-833-473-697-303; 053-911-933-622-849; 054-171-536-091-904; 055-131-409-231-142; 055-538-836-733-096; 057-062-724-962-54X; 058-231-498-964-619; 058-742-137-103-13X; 059-289-919-542-114; 061-161-984-486-234; 062-616-354-130-588; 062-778-866-870-370; 063-073-867-011-793; 063-332-201-370-750; 063-483-909-050-195; 065-486-149-160-119; 066-366-141-687-389; 067-162-581-381-860; 067-515-831-168-01X; 067-809-546-017-427; 068-905-504-774-434; 069-266-136-249-73X; 070-834-694-189-784; 071-282-460-335-770; 073-830-452-550-646; 075-962-490-026-551; 076-799-764-361-357; 079-652-083-917-340; 081-618-868-761-086; 084-039-282-291-550; 084-051-392-552-266; 085-139-441-182-357; 086-196-868-592-176; 087-827-326-061-711; 089-187-222-527-134; 091-785-760-212-123; 092-881-907-547-945; 094-132-495-303-526; 096-258-695-381-365; 096-560-045-404-980; 096-586-583-854-300; 097-282-097-251-751; 097-284-901-443-201; 098-082-474-840-130; 098-668-994-875-896; 098-972-464-406-597; 101-100-831-208-09X; 102-881-261-628-869; 103-870-273-365-288; 104-113-052-296-627; 104-889-475-186-487; 106-847-189-949-33X; 107-944-130-818-141; 110-086-240-302-349; 110-610-720-322-224; 111-280-227-934-048; 111-526-694-724-856; 113-654-439-988-458; 114-582-110-050-559; 114-733-336-770-749; 114-798-080-208-716; 115-906-186-801-413; 116-970-365-700-709; 117-100-985-844-153; 118-096-377-140-686; 121-360-045-012-862; 122-827-252-276-011; 122-959-231-867-60X; 123-165-910-155-120; 123-905-840-486-207; 125-320-367-140-786; 125-460-939-653-873; 125-938-028-951-159; 128-011-949-615-227; 129-120-491-913-159; 129-296-274-479-818; 129-394-271-826-748; 130-807-078-850-023; 134-737-520-552-470; 135-194-352-803-91X; 135-589-047-152-766; 136-297-173-709-010; 136-513-894-311-962; 138-145-365-539-917; 141-409-340-772-194; 141-425-686-978-878; 147-047-917-758-50X; 148-759-251-450-067; 149-262-670-702-92X; 150-094-228-937-860; 150-233-872-967-013; 151-206-677-182-598; 155-182-885-430-076; 156-508-142-099-734; 157-020-388-867-139; 157-733-902-989-711; 158-065-515-628-065; 159-556-988-914-486; 161-217-536-979-014; 167-017-558-746-803; 167-932-936-923-088; 174-355-650-961-43X; 174-382-134-203-53X; 174-767-529-029-940; 180-942-705-428-020; 182-447-911-220-575; 183-158-210-699-355; 185-577-192-905-213; 189-103-197-645-730; 189-747-266-858-291; 190-705-303-579-268; 196-727-696-984-146,0,true,cc-by,gold -087-485-906-174-360,Measurement and conceptualization of male involvement in family planning: a bibliometric analysis of Africa-based studies.,2024-06-13,2024,journal article,Contraception and reproductive medicine,20557426,Springer Science and Business Media LLC,England,Tosin Olajide Oni; Rebaone Petlele; Olufunmilayo Olufunmilola Banjo; Akinrinola Bankole; Akanni Ibukun Akinyemi,"Male involvement in Family Planning (FP) is an exercise of men's sexual and reproductive health rights. However, the measurement of male involvement has been highly inconsistent and too discretional in FP studies. As a result, we used bibliometric tools to analyze the existing measures of male involvement in FP and recommend modifications for standard measures.; Using developed search terms, we searched for research articles ever published on male involvement in FP from Scopus, Web of Science, and PubMed databases. The search results were filtered for studies that focused on Africa. A total of 152 research articles were selected after the screening, and bibliometric analysis was performed in R.; Results showed that 54% of the studies measured male involvement through approval for FP, while 46.7% measured it through the attitude of males to FP. About 31% measured male involvement through input in deciding FP method, while others measured it through inputs in the choice of FP service center (13.6%), attendance at FP clinic/service center (17.8%), and monetary provision for FP services/materials (12.4%). About 82.2% of the studies used primary data, though the majority (61.2%) obtained information on male involvement from women alone. Only about one in five studies (19.1%) got responses from males and females, with fewer focusing on males alone.; Most studies have measured male involvement in FP through expressed or perceived approval for FP. However, these do not sufficiently capture male involvement and do not reflect women's autonomy. Other more encompassing measures of male involvement, which would reflect the amount of intimacy among heterosexual partners, depict the extent of the exercise of person-centered rights, and encourage the collection of union-specific data, are recommended.; © 2024. The Author(s).",9,1,29,,Attendance; Scopus; Conceptualization; Medicine; Family planning; Web of science; Reproductive health; Demography; Family medicine; Psychology; Gynecology; MEDLINE; Meta-analysis; Research methodology; Internal medicine; Political science; Population; Sociology; Environmental health; Artificial intelligence; Computer science; Law,Africa; Family planning; Male involvement; Measurements; Men,,,,https://contraceptionmedicine.biomedcentral.com/counter/pdf/10.1186/s40834-024-00293-9 https://doi.org/10.1186/s40834-024-00293-9,http://dx.doi.org/10.1186/s40834-024-00293-9,38867339,10.1186/s40834-024-00293-9,,PMC11170783,0,000-588-456-049-68X; 002-303-687-492-33X; 005-237-881-312-255; 007-445-385-432-556; 008-446-880-538-471; 008-575-071-734-668; 009-312-897-224-164; 012-938-611-000-61X; 013-124-029-603-777; 013-177-686-464-737; 013-507-404-965-47X; 013-704-081-088-419; 016-849-440-919-066; 018-209-302-057-610; 022-360-341-949-626; 022-512-457-915-532; 024-287-939-892-008; 029-691-787-464-368; 030-003-082-757-56X; 033-239-256-485-921; 033-383-214-423-729; 033-822-302-991-349; 035-347-898-696-676; 038-890-390-600-307; 041-042-215-649-054; 046-371-684-061-340; 048-450-102-183-910; 052-347-582-890-452; 053-211-567-582-818; 053-435-052-598-805; 054-045-418-637-913; 060-166-862-957-057; 065-638-393-210-966; 067-199-358-115-200; 068-258-489-642-792; 071-439-031-638-557; 076-547-958-068-182; 079-250-785-412-134; 081-463-729-746-536; 100-138-513-067-102; 101-216-532-371-879; 104-574-631-335-311; 106-527-039-400-250; 113-594-124-035-028; 115-042-665-448-738; 123-465-585-160-157; 128-156-730-150-282; 138-730-315-964-197; 140-382-033-831-963; 184-716-896-956-183,1,true,"CC BY, CC0",gold -087-548-909-435-322,Foundations and knowledge clusters in TikTok (Douyin) research: evidence from bibliometric and topic modelling analyses,2023-09-20,2023,journal article,Multimedia Tools and Applications,15737721; 13807501,Springer Science and Business Media LLC,Netherlands,Abderahman Rejeb; Karim Rejeb; Andrea Appolloni; Horst Treiblmaier,"AbstractThe goal of this study is to comprehensively analyze the dynamics and structure of TikTok research since its initial development. The scholarly composition of articles dealing with TikTok was dissected via a bibliometric study based on a corpus of 542 journal articles from the Scopus database. The results show that TikTok research has flourished in recent years and also demonstrate that the authors’ collaboration networks are disjointed, indicating a lack of cooperation among TikTok researchers. Furthermore, the analysis reveals that research collaboration among academic institutions reflects the North-South divide, also highlighting a limited research collaboration between institutions in developed and developing countries. Based on the keyword co-occurrence network and topic modeling, TikTok research revolves mainly around five thematic areas, including public health, health communication and education, platform governance, body image, and its impact on children and students. Based on these findings, numerous suggestions for further research are offered. As far as the authors are aware, this is the first application of bibliometrics and topic modeling to assess the growth of TikTok research and reveal the intellectual base of this knowledge domain.",83,11,32213,32243,Scopus; Bibliometrics; Computer science; Domain (mathematical analysis); Corporate governance; Thematic analysis; Knowledge management; Data science; Qualitative research; Social science; MEDLINE; Library science; Sociology; Political science; Business; Mathematical analysis; Mathematics; Finance; Law,,,,MODUL University Vienna GmbH,https://link.springer.com/content/pdf/10.1007/s11042-023-16768-x.pdf https://doi.org/10.1007/s11042-023-16768-x,http://dx.doi.org/10.1007/s11042-023-16768-x,,10.1007/s11042-023-16768-x,,,0,000-203-627-584-442; 001-038-185-082-41X; 001-402-752-508-543; 001-632-924-218-694; 003-781-074-169-604; 004-026-735-814-111; 005-982-734-572-436; 006-835-404-158-175; 007-016-826-558-870; 007-141-694-325-68X; 007-254-442-793-429; 007-947-222-219-419; 008-918-091-923-652; 009-037-581-121-982; 009-860-878-085-063; 010-873-540-260-15X; 011-015-922-245-209; 011-305-515-235-690; 011-376-526-374-758; 012-127-498-792-141; 013-507-265-959-298; 013-525-173-304-007; 014-185-469-790-292; 014-939-376-763-015; 016-231-662-844-528; 016-587-091-103-503; 016-882-677-420-575; 017-022-607-700-789; 017-265-292-897-535; 019-145-257-936-240; 019-192-723-072-550; 019-731-115-116-919; 019-764-117-584-856; 019-796-917-215-553; 019-903-418-172-561; 022-216-189-843-184; 022-320-724-884-923; 022-415-856-801-60X; 023-767-197-554-144; 025-065-124-384-603; 025-537-243-901-610; 027-258-283-855-533; 027-266-271-375-436; 028-805-520-529-245; 030-884-614-442-28X; 031-304-465-937-977; 033-389-095-931-161; 034-573-796-158-534; 034-993-133-281-591; 035-378-718-873-615; 036-058-758-172-251; 037-925-111-297-829; 039-282-350-646-738; 042-025-040-287-419; 042-282-651-296-661; 043-007-817-954-581; 043-861-740-564-253; 044-497-794-285-274; 044-788-266-057-956; 046-069-268-507-318; 046-647-782-650-493; 047-078-751-169-348; 047-134-478-431-993; 051-614-328-082-377; 051-716-236-618-864; 052-621-009-773-826; 052-893-986-572-352; 053-282-167-652-782; 053-877-326-178-33X; 054-083-521-443-620; 054-842-941-091-224; 056-592-888-688-921; 056-749-163-648-175; 060-724-421-296-728; 061-043-387-689-300; 064-158-745-887-681; 067-164-171-987-113; 067-461-470-339-184; 067-779-688-252-567; 067-972-776-852-225; 072-749-446-541-669; 073-082-540-323-24X; 075-151-153-785-232; 075-605-057-579-627; 075-991-637-398-855; 076-233-070-072-670; 079-220-347-656-115; 080-309-356-193-622; 081-588-603-492-525; 081-982-317-454-515; 085-159-530-193-996; 087-623-656-698-219; 088-920-524-633-912; 089-370-370-337-266; 089-421-841-756-22X; 092-078-224-947-509; 092-416-936-225-669; 093-767-602-052-949; 095-677-271-227-401; 095-955-756-476-024; 098-892-637-962-816; 099-014-284-546-688; 100-846-953-745-920; 101-142-804-957-269; 101-729-171-121-99X; 101-865-472-120-022; 103-352-228-285-510; 104-495-326-573-684; 104-519-078-998-352; 109-628-701-374-387; 109-975-357-308-511; 110-621-950-675-061; 110-666-571-061-317; 110-977-350-231-077; 112-980-318-660-429; 113-882-349-413-233; 116-350-652-666-921; 118-227-163-882-243; 120-550-764-757-570; 120-974-286-046-262; 123-435-704-277-693; 123-830-565-962-550; 124-421-256-318-066; 125-281-073-786-515; 127-947-687-982-546; 129-152-466-982-693; 130-057-480-639-007; 133-500-145-350-92X; 134-366-982-952-006; 135-189-641-687-525; 135-578-699-334-529; 138-991-403-049-285; 141-200-607-894-303; 150-214-033-528-999; 154-031-573-618-251; 154-387-088-722-458; 157-907-694-855-168; 161-411-160-085-168; 161-446-676-354-613; 165-213-269-306-233; 165-488-276-451-124; 173-922-225-536-012; 175-676-148-870-077; 179-817-721-984-176; 179-919-840-555-451; 184-280-105-967-245; 188-039-999-979-708; 190-106-693-083-326,6,true,cc-by,hybrid -088-108-398-231-703,Bibliometrix analysis of information sharing in social media,2022-01-23,2022,journal article,Cogent Business & Management,23311975,Informa UK Limited,,Alhamzah F. Abbas; Ahmad Jusoh; Adaviah Mas'od; Ahmed H. Alsharif; Javed Ali,"Social media has evolved at a rapid pace, influencing every aspect of the global community. The purpose of this paper is to use bibliometric analysis tools to evaluate valid works on the relationship between social media and information sharing. A review study of research papers on social media and information sharing published between 2009 and 2020 was conducted. The bibliometric analysis identified the following characteristics: (1) the primary articles are based on information sharing through social media; (2) the main authors deal with information sharing in social media; (3) the newestrend topics related to information sharing in social media are demographic characteristics, cognition, sentiment, healthcare, products and services recommendations, tourist recommendations, and COVID-19. The results show significant impact rates in studies of information sharing in social media. Overall, this study serves as a basis for new scientific questions that will contribute to the further development of this research field.",9,1,,,Social media; Pace; Information sharing; Microblogging; Tourism; Field (mathematics); Knowledge management; Computer science; Data science; World Wide Web; Political science; Geography; Mathematics; Geodesy; Pure mathematics; Law,,,,no direct funding,,http://dx.doi.org/10.1080/23311975.2021.2016556,,10.1080/23311975.2021.2016556,,,0,000-131-032-567-15X; 000-390-751-024-692; 003-894-966-706-656; 004-288-931-757-177; 005-402-845-141-491; 007-141-694-325-68X; 011-110-332-620-385; 013-507-404-965-47X; 014-129-634-820-525; 017-592-318-524-541; 017-750-600-412-958; 019-740-986-808-907; 024-250-992-858-248; 026-451-107-495-784; 026-845-733-807-089; 026-926-948-262-287; 028-622-611-461-571; 030-232-730-937-577; 031-317-385-656-473; 031-611-206-953-788; 034-837-265-172-536; 035-039-932-749-109; 040-757-646-863-936; 042-311-967-349-336; 043-283-160-768-784; 044-363-087-441-895; 047-134-478-431-993; 049-004-045-436-622; 057-277-003-666-474; 060-677-444-944-717; 060-728-651-859-600; 061-463-167-854-643; 063-026-272-816-478; 064-221-979-927-26X; 064-362-712-101-345; 065-113-818-298-990; 070-020-736-574-494; 070-749-933-429-663; 073-583-967-569-818; 076-472-252-292-488; 080-678-969-626-607; 081-034-687-932-115; 083-925-625-829-149; 086-022-664-885-321; 090-752-383-579-896; 090-994-824-033-330; 091-383-939-895-049; 092-185-132-363-147; 100-374-731-471-095; 101-353-284-490-924; 107-170-167-586-771; 122-472-332-293-399; 122-906-503-445-808; 141-264-756-049-894; 145-613-893-184-484; 149-637-696-736-608; 154-573-681-858-881; 156-142-407-524-609; 157-438-300-788-670; 178-841-402-537-081; 179-265-414-559-468; 184-280-105-967-245,69,true,cc-by,gold -088-124-550-991-476,Differentiated Learning Model in Writing News Texts: a Bibliometrix,,2024,conference proceedings article,"Proceedings of the 3rd International Conference of Humanities and Social Science, ICHSS 2023, December 27, 2023, Surakarta, Central Java, Indonesia",,EAI,,Ibrahim Soleh; Suyitno Suyitno; Setiawan Budhi,,,,,,Computer science; Natural language processing; Artificial intelligence; Linguistics; Philosophy,,,,,,http://dx.doi.org/10.4108/eai.27-12-2023.2351573,,10.4108/eai.27-12-2023.2351573,,,0,,0,false,, -088-165-992-760-588,Ecological risk assessment of emerging contaminants on soil and terrestrial ecosystems (2005-2024): a bibliometric and scientometric review.,2025-04-22,2025,journal article,Environmental geochemistry and health,15732983; 02694042,Springer Science and Business Media LLC,Netherlands,Wen Ma; Qi Wang; Erastus Mak-Mensah; Xiaole Zhao; Wenjia Qi; Jinhui Zhu; Rizwan Azim; Xujiao Zhou; Dengkui Zhang; Bing Liu; Qinglin Liu; Xuchun Li,,47,5,179,,Environmental science; Contamination; Terrestrial ecosystem; Ecosystem; Soil contamination; Ecology; Environmental chemistry; Biology; Chemistry,Ecological risk assessment; Emerging contaminants; Environmental monitoring; Microplastics; Soil contamination,Humans; Bibliometrics; Ecosystem; Environmental Monitoring; Risk Assessment; Soil Pollutants/analysis,Soil Pollutants,"National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); National Natural Science Foundation of China (42061050); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Natural Science Foundation of Gansu Province, China (22JR5RA849); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036); Major Science and Technology Projects of Gansu Province in 2022 - International Science and Technology Cooperation Projects (22ZD6WA036)",,http://dx.doi.org/10.1007/s10653-025-02486-w,40259118,10.1007/s10653-025-02486-w,,,0,000-693-210-259-577; 001-461-945-988-010; 001-508-294-809-482; 003-194-115-373-972; 005-828-306-256-749; 007-085-406-430-140; 010-817-247-153-906; 011-436-274-175-032; 011-679-009-944-693; 011-837-073-982-978; 014-769-154-847-96X; 014-943-675-746-321; 017-171-296-577-881; 021-510-730-636-580; 024-284-700-168-620; 024-375-288-851-578; 027-322-052-827-483; 031-139-518-653-18X; 031-922-088-768-28X; 035-540-277-987-969; 037-875-336-322-965; 043-971-197-139-358; 052-156-276-916-253; 056-199-494-685-209; 058-770-055-244-391; 058-989-620-346-777; 067-154-369-055-945; 073-707-792-585-630; 075-276-427-096-768; 075-402-466-926-570; 077-164-046-298-637; 091-883-226-579-864; 092-185-651-613-435; 109-811-327-706-788; 121-512-709-169-804; 138-053-913-794-217; 142-715-623-493-277; 160-715-165-810-900; 177-716-058-982-194; 183-750-736-233-720,0,false,, -089-339-142-917-132,Industry 5.0 as seen through its academic literature: an investigation using co-word analysis,2025-04-19,2025,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Abderahman Rejeb; Karim Rejeb; Imen Zrelli; Edit Süle,"Abstract; Industry 5.0 marks a pivotal advancement in manufacturing and bridges cutting-edge technology with human creativity to enhance efficiency, sustainability, and workplace dynamics. Despite its growing relevance, there remains a significant knowledge gap due to the lack of comprehensive reviews that synthesize the breadth of research and practice in this rapidly evolving field. This paper presents a comprehensive bibliometric analysis of Industry 5.0 and examines a corpus of 915 journal articles from the Scopus database, spanning from January 2016 to May 2024. The study aims to map the evolving landscape and thematic trajectories of Industry 5.0, highlighting its integration with advanced technologies such as AI, IoT, and human-centric systems. The findings indicate significant trends in the field, including a shift from theoretical underpinnings to practical applications and the growing emphasis on sustainability and human–machine collaboration. These thematic areas highlight the transformative potential of Industry 5.0 to enhance operational efficiency, workplace dynamics, and environmental sustainability within the industrial sector. By employing bibliometric and co-word analysis, this study addresses existing knowledge gaps and provides a nuanced understanding of the interdisciplinary interactions and future directions in Industry 5.0. The findings reveal the critical role of emerging technologies in driving the next industrial revolution, suggesting that future research should focus on integrating these technologies with socio-economic objectives to fully realize the potential of Industry 5.0. In terms of originality, this study sets a foundation for future explorations and practical implementations that can contribute to more sustainable, efficient, and human-centric industrial practices.",6,1,,,Word (group theory); Psychology; Linguistics; Computer science; Philosophy,,,,Széchenyi István University,,http://dx.doi.org/10.1007/s43621-025-01166-0,,10.1007/s43621-025-01166-0,,,0,002-675-386-476-536; 004-848-638-188-975; 006-388-724-462-537; 007-143-970-984-059; 009-725-897-636-244; 010-107-782-741-893; 011-847-162-085-549; 012-924-603-093-011; 013-507-404-965-47X; 013-541-969-076-695; 017-415-713-662-955; 018-537-060-605-321; 020-821-233-783-792; 022-943-664-043-241; 025-018-146-195-019; 025-537-243-901-610; 028-232-581-949-707; 028-319-033-520-661; 029-173-073-052-054; 030-655-597-589-781; 031-149-083-083-331; 031-540-666-653-73X; 032-357-017-579-454; 032-528-436-685-845; 033-034-731-916-147; 036-391-860-196-240; 037-730-846-958-819; 043-419-424-162-47X; 043-544-886-611-64X; 043-916-901-078-607; 044-151-611-794-538; 045-789-186-045-26X; 046-391-057-701-319; 046-504-796-363-470; 046-693-398-242-29X; 047-134-478-431-993; 047-344-167-153-151; 048-095-661-190-101; 048-152-873-055-217; 048-840-098-633-459; 049-000-866-151-423; 049-303-089-841-806; 049-391-379-302-694; 049-695-810-690-712; 050-312-235-979-935; 051-583-755-164-538; 051-647-739-244-271; 052-616-783-435-969; 052-893-986-572-352; 053-158-040-811-696; 053-465-468-285-420; 053-848-476-794-258; 054-322-954-108-815; 055-694-149-090-820; 056-132-718-533-671; 057-072-124-885-631; 058-288-722-477-215; 064-138-810-036-202; 065-298-866-832-768; 066-608-381-243-647; 067-215-875-080-779; 067-779-688-252-567; 070-094-343-672-60X; 070-673-790-875-288; 071-897-037-799-229; 071-997-321-346-321; 072-085-186-569-040; 072-959-739-837-266; 075-662-363-625-645; 076-820-557-788-60X; 078-002-849-643-574; 079-648-541-389-775; 080-203-551-413-090; 081-258-162-379-866; 081-523-568-781-26X; 081-820-235-771-46X; 082-196-736-655-010; 083-870-505-444-767; 084-237-659-335-312; 085-708-655-087-010; 086-217-750-686-732; 090-332-878-930-771; 098-332-178-744-389; 098-931-517-571-73X; 099-324-130-493-556; 101-597-275-400-799; 104-089-062-123-765; 104-495-326-573-684; 106-482-786-882-613; 106-567-081-505-327; 107-831-670-078-761; 107-928-438-583-035; 111-131-178-725-354; 111-534-063-351-205; 113-830-545-572-413; 114-501-464-535-919; 114-693-476-631-202; 114-716-932-289-180; 115-093-711-312-12X; 115-262-469-363-328; 117-412-387-103-550; 120-381-251-057-750; 122-463-285-024-596; 125-795-343-058-314; 132-020-371-862-297; 133-479-177-347-406; 133-837-373-445-908; 134-752-888-453-900; 134-951-675-710-143; 135-401-178-888-135; 136-132-971-012-829; 136-738-026-200-485; 137-427-710-629-630; 138-325-137-052-478; 138-332-915-687-580; 138-963-354-684-080; 140-109-678-513-738; 142-998-026-914-988; 143-421-594-525-745; 145-761-029-580-825; 148-089-014-742-699; 150-082-593-676-592; 150-681-306-325-664; 150-929-169-039-712; 150-985-024-767-053; 151-036-194-360-653; 153-521-098-651-081; 157-615-862-617-122; 158-477-188-542-31X; 160-671-580-903-387; 161-031-993-440-035; 162-000-543-973-648; 162-808-642-156-338; 162-955-280-594-444; 164-022-945-594-480; 167-016-942-115-219; 167-090-539-907-932; 172-222-577-432-985; 173-095-745-399-772; 173-142-179-208-343; 173-318-125-964-836; 173-984-421-089-065; 173-989-857-453-959; 179-491-876-461-284; 179-827-640-108-173; 185-034-942-123-157; 185-979-332-812-396; 186-083-195-011-844; 186-582-203-460-217; 186-938-325-804-510; 187-215-751-487-551; 188-842-502-849-928; 189-665-202-075-918; 191-295-792-752-734; 191-799-734-492-11X; 192-760-347-619-617; 193-156-474-237-481; 194-408-206-196-374; 198-242-705-126-205,0,true,cc-by,gold -089-402-839-586-467,Escaneo científico sobre tendencias en agroecología,,2024,report,,,Corporación colombiana de investigación agropecuaria - AGROSAVIA,,ALEXIS MORALES CASTAÑEDA,"La agroecología ha ganado relevancia como enfoque estratégico para enfrentar retos ambientales, climáticos y alimentarios mediante prácticas agrícolas sostenibles. Este estudio analizó 1.198 publicaciones científicas sobre agroecología entre 2019 y 2023, extraídas de Scopus® mediante una ecuación de búsqueda especializada. A través de herramientas como Bibliometrix® y VOSviewer®, se identificaron tendencias clave y clústeres temáticos que reflejan la evolución del conocimiento en agroecosistemas, resiliencia, soberanía alimentaria y sostenibilidad, proporcionando insumos para orientar agendas de investigación y políticas públicas en el sector agropecuario.",,,,,,,,,,,http://dx.doi.org/10.21930/agrosavia.escaneocientifico.2024.3,,10.21930/agrosavia.escaneocientifico.2024.3,,,0,,0,false,, -089-410-503-153-107,Global research trends in mind body therapies: a bibliometric analysis.,2025-03-24,2025,journal article,Journal of translational medicine,14795876,Springer Science and Business Media LLC,United Kingdom,Yunxiao Zhang; Wenwen Li; Sai Xu; Shudi Li; Zhen Hai Sun; Menghe Zhang; Yaoyao Zuo; Shouqiang Chen,"Mind-body therapies are a group of treatments based on the theory of mind-body medicine, which are effective for a wide range of illnesses. However, there are no bibliometric papers that have examined the topic of mind-body therapies. Therefore, it is necessary to review and sort out the current status, hotspots and frontiers of mind-body therapies.; Studies related to mind-body therapies during the period of Web of Science 1999-01/2024-07 were searched, and R language was applied to analyze the data and CiteSpace, Vosviewer software, was used to generate visualization maps.; A total of 29,710 relevant articles were included in the study. The country with the highest number of publications was the United States, followed by China and the United Kingdom, and the prolific author was Wang Yuan. Common keywords were acupuncture, quality of life, depression, and pain. The current study focuses on the promotion and application of mind-body therapies in various diseases, the main applicable diseases and the application in special groups.; This study presents the current status and trend of research on mind-body therapies, and inflammatory interventions and higher-level research assessment methods are potential hotspots, which can help researchers to clarify hotspots and explore new directions.; © 2025. The Author(s).",23,1,365,,Bibliometrics; MEDLINE; Medicine; Data science; Computer science; Library science; Biology; Biochemistry,Bibliometric analysis; CiteSpace; Mind-body therapies; VOSviewer; Visualization,Bibliometrics; Humans; Mind-Body Therapies/trends; Internationality; Biomedical Research/trends,,Construction of Traditional Chinese Medicine science and technology project of Shandong Province (No. Z-2023010); Shandong traditional Chinese medicine science and technology project (No.: M - 2023260); Shandong traditional Chinese medicine science and technology project (No.: M - 2023144),https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/s12967-025-06389-3 https://doi.org/10.1186/s12967-025-06389-3,http://dx.doi.org/10.1186/s12967-025-06389-3,40128872,10.1186/s12967-025-06389-3,,PMC11934818,0,000-099-180-329-930; 000-667-231-896-402; 002-147-799-928-773; 002-281-362-707-430; 002-726-035-765-069; 004-155-437-378-180; 005-688-443-247-273; 006-019-224-211-586; 006-435-438-364-476; 008-671-156-753-729; 009-717-031-730-74X; 010-066-017-792-214; 010-082-741-463-120; 010-598-037-888-771; 011-301-822-302-672; 011-488-788-822-721; 011-729-413-900-185; 013-414-142-802-247; 017-354-069-206-804; 018-355-093-288-02X; 021-098-622-965-289; 021-598-093-840-35X; 022-210-192-685-28X; 023-933-390-012-751; 027-202-221-458-45X; 027-504-703-899-892; 030-437-597-970-747; 032-074-212-992-842; 034-724-086-609-818; 039-038-734-128-345; 041-799-849-645-121; 042-372-852-105-840; 044-926-871-925-443; 045-071-538-985-501; 055-190-910-168-36X; 064-718-880-279-876; 065-172-368-020-448; 065-175-370-321-681; 066-491-189-503-086; 067-392-134-585-494; 069-143-731-494-932; 069-169-976-423-994; 071-516-173-407-523; 073-249-837-479-044; 075-122-312-996-289; 078-184-993-278-620; 078-229-464-847-994; 080-568-307-765-598; 082-126-342-430-560; 087-214-302-845-165; 087-979-454-457-668; 088-535-076-365-000; 088-569-984-928-820; 091-328-965-270-227; 091-505-043-290-533; 092-567-546-617-219; 094-009-915-865-629; 094-484-979-870-235; 095-438-682-265-682; 098-221-834-966-210; 105-399-266-432-324; 108-096-958-113-018; 110-695-129-057-713; 115-250-050-227-409; 121-489-350-620-183; 123-428-120-530-442; 126-084-624-916-464; 133-415-197-738-241; 142-492-497-934-389; 143-260-294-107-395; 150-063-547-412-47X; 154-090-584-092-881; 163-083-990-499-848; 175-351-971-829-999; 178-210-449-492-414; 183-121-872-943-100; 185-215-425-691-546,0,true,"CC BY, CC0",gold -089-428-348-220-933,Beyond the Boundary: A Bibliometric Analysis of the Published Research on Injuries in Cricket.,2023-08-23,2023,journal article,Indian journal of orthopaedics,00195413; 19983727,Springer Science and Business Media LLC,India,Mandeep S Dhillon; Sandeep Patel; Siddhartha Sharma,"Cricket, a sport immensely popular in the Indian subcontinent and Commonwealth countries, boasts a staggering global following of over 1 billion enthusiasts. However, injuries in cricket are prevalent, resulting in detrimental effects on player performance and leading to substantial absenteeism from the game. In recent times, there has been a surge in interest on the epidemiology, biomechanics, and prevention of cricket-related injuries. To gain comprehensive insights into the existing research landscape, we present a bibliometric analysis of the published research on cricket injuries.; The Web of Science database was searched using a well-defined search strategy. Original research articles looking at any aspect of injuries in cricket were included. Search results were imported into the R Bibliometrix package for analysis. Analysis of bibliometric parameters included top authors, journals, countries and keywords. Co-occurrence networks were generated and thematic mapping was performed to identify emerging research topics.; 423 publications from 126 journals were included. An increasing trend in publications was noted. JW Orchard was the highest published author; Australia was the highest published country and the Journal of Science and Sport in Medicine had the highest number of publications. Fast bowlers were the most extensively researched and the major research was noted to focus on three niche areas, i.e., epidemiology, consensus definitions and spinal issues in fast bowlers. Research on batsmen, wicketkeepers and fielders was relatively sparse. Furthermore, we observed limited representation of research from the Indian subcontinent, despite cricket's immense popularity in the region.; Our study findings highlight that majority of the cricket injury research stems from developed countries. The primary research areas include epidemiology, injury prevention, and biomechanics, with a particular focus on fast bowlers. However, much more has to be done to encourage research publications, focused on batsmen, wicketkeeper and fielders, as well as cricket in the developing world. These insights are essential for researchers seeking to delve into cricket-related studies and organizations aiming to advance injury prevention research in cricket.; © Indian Orthopaedics Association 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.",57,10,1575,1583,Medicine; Cricket; Aeronautics; Library science; Engineering; Computer science; Ecology; Biology,Batsmen; Bibliometrics; Bowlers; Cricket; Injuries; Scientometrics; Sports,,,,,http://dx.doi.org/10.1007/s43465-023-00973-9,37766943,10.1007/s43465-023-00973-9,,PMC10519880,0,004-227-497-657-093; 013-507-404-965-47X; 043-352-672-844-898; 046-992-864-415-70X; 067-540-900-322-928; 072-880-866-012-679; 089-913-266-705-178; 102-998-678-345-732; 106-686-911-212-729; 122-360-485-346-424; 180-087-500-837-854,1,true,,green -089-578-935-943-865,Cultural Heritage Tourism and Sustainability: A Bibliometric Analysis,2024-07-26,2024,journal article,Sustainability,20711050,MDPI AG,Switzerland,Recep Murat Geçikli; Orhan Turan; Lenka Lachytová; Erkan Dağlı; Murad Alpaslan Kasalak; Sinem Burcu Uğur; Yigit Guven,"Cultural heritage tourism is a very important issue for the cultural transfer and sustainability of tourism. In parallel, cultural heritage tourism in the context of sustainability has become a popular field that has attracted the attention of researchers in recent years. Therefore, this study aims to analyze international publications on the relationship between cultural heritage tourism and sustainability, identifying trends in development and future research opportunities. Based on this purpose, 657 related studies have been found in the Web of Science database and analyzed in the Bibliometrix R package to map and systematically review the literature. By focusing specifically on the relationship between cultural heritage and sustainability, this study fills a gap in the existing literature, which often handles these issues separately. In addition, the research results contain valuable information that can shape future research agendas.",16,15,6424,6424,Sustainability; Tourism; Cultural heritage; Context (archaeology); Heritage tourism; Cultural heritage management; Tourism geography; Political science; Industrial heritage; Cultural sustainability; Sustainable tourism; Environmental resource management; Environmental planning; Sociology; Geography; Archaeology; Economics; Ecology; Biology,,,,,https://www.mdpi.com/2071-1050/16/15/6424/pdf?version=1722766369 https://doi.org/10.3390/su16156424,http://dx.doi.org/10.3390/su16156424,,10.3390/su16156424,,,0,002-139-196-713-079; 002-452-090-964-022; 008-877-699-392-61X; 010-823-801-809-732; 012-451-875-954-500; 013-507-404-965-47X; 013-510-550-141-556; 020-433-578-752-831; 025-114-783-268-196; 026-233-450-399-209; 027-454-844-935-225; 028-144-957-217-53X; 031-773-373-281-992; 032-328-271-181-991; 032-728-374-962-11X; 042-568-239-705-957; 042-661-997-015-409; 043-122-429-872-430; 044-469-997-624-469; 051-942-857-883-535; 062-541-050-791-025; 064-373-405-259-63X; 065-186-465-808-074; 066-329-628-156-958; 066-849-661-222-258; 071-856-935-801-588; 071-878-836-294-733; 074-707-731-021-678; 076-945-247-218-731; 078-492-662-100-988; 079-070-675-840-033; 086-242-877-234-543; 097-653-820-557-144; 100-215-639-074-996; 102-525-058-492-432; 102-703-470-977-772; 105-710-172-109-007; 106-890-360-877-844; 110-655-303-208-438; 112-062-468-179-355; 112-983-991-799-221; 115-869-158-136-428; 117-385-655-408-270; 120-112-470-779-90X; 126-600-458-535-591; 129-738-093-931-620; 137-915-834-689-865; 138-554-672-951-167; 138-874-820-481-981; 141-094-715-418-842; 144-841-277-664-853; 174-093-643-192-911; 186-286-739-382-863; 187-124-468-167-399; 190-771-338-440-608; 193-946-461-032-459; 194-853-190-595-340; 199-810-681-206-989,9,true,,gold -089-685-510-924-558,Exploring the potential of chestnut (Castanea sativa Mill.): a comprehensive review and conceptual mapping,2024-08-27,2024,journal article,Bulletin of the National Research Centre,25228307,Springer Science and Business Media LLC,,Siddig Ibrahim Abdelwahab; Manal Mohamed Elhassan Taha; Ieman Aljahdali; Bassem Oraibi; Amal Alzahrani; Abdullah Farasani; Hassan Alfaifi; Yasir Babiker,"Abstract; Background; Castanea sativa Mill. is important for ecosystems and societies. Its rich historical and cultural significance, remarkable ecological contributions, and diverse applications have inspired scientific research. This comprehensive review and conceptual mapping of chestnut research consolidates existing knowledge, identifies emerging trends, and highlights untapped potential to inform future investigations. First, the Scopus database was searched to retrieve all data-driven articles in English related to C. sativa published in English from 1951 to 2023. Second, the R language, Scopus Analytics, and VOSviewer were used to analyze the year of publication, authors, countries, affiliations, keywords, and citations. Finally, network analysis was performed to evaluate the hotspots and developmental trends of C. sativa. A total of 1889 research articles were recovered.; ; Results; The articles showed an exponential progression, with a regression coefficient of 0.9435 (R2) and an annual growth rate of 6.28%. Italy (19.87%), Spain (15.56%), Portugal (13.39%), Turkey (6.92%), and Switzerland (5.17%) were the most prolific countries. C. sativa (798), sweet chestnut (54), cryphonectria parasitica (44), honey (38), phenolic compounds (35), chestnut blight (33) and antioxidant activity (31) are the keywords that occur the most frequently. The main research groups in the thematic map are ""forest management,"" ""Cryphonectria parasitica,"" ""wood,"" ""Spain"" and ""ethnobotany."" Research on C. sativa has all the basic, motor, niche, and emerging or declining themes. Forest management, drought, Gnomoniopsis smithogilvyi, C. sativa shells, amino acids, honey, phenolic compounds, hydrolyzable tannins, antioxidant capacity, antioxidants, and extractives are trending topics.; ; Conclusions; This bibliometric analysis highlights the importance of C. sativa research, revealing its ecological contributions, cultural significance, and diverse applications. Future studies should focus on forest management, drought resistance, and bioactive properties to ensure sustainable utilization.; ",48,1,,,Mill; Geography; Archaeology,,,,Jazan University,,http://dx.doi.org/10.1186/s42269-024-01238-7,,10.1186/s42269-024-01238-7,,,0,002-052-422-936-00X; 003-269-528-387-698; 004-779-708-224-462; 006-183-082-663-273; 007-070-521-238-988; 008-482-505-071-353; 009-211-577-499-764; 012-804-203-421-403; 013-507-404-965-47X; 014-689-405-284-648; 015-599-330-973-840; 016-377-310-729-94X; 017-572-486-009-110; 017-588-457-124-669; 018-265-683-899-147; 018-937-920-422-799; 019-145-529-578-652; 025-389-345-284-682; 027-256-272-073-254; 030-101-942-250-937; 036-340-921-232-744; 037-006-511-558-699; 037-426-339-293-65X; 040-281-675-483-878; 042-301-443-063-434; 050-116-580-336-887; 056-919-356-833-229; 061-038-747-180-430; 065-638-441-995-850; 066-221-209-955-881; 067-286-619-148-533; 068-576-708-682-65X; 076-498-170-063-038; 077-652-568-573-07X; 087-703-924-728-219; 087-993-789-071-872; 089-768-929-232-546; 093-023-986-319-718; 096-922-073-206-282; 112-107-672-070-863; 116-102-679-468-121; 117-872-333-061-786; 127-514-288-543-948; 130-988-375-836-645; 142-968-326-874-837; 146-571-028-984-149; 156-222-669-723-595; 156-519-405-250-701; 160-603-873-418-719; 162-589-030-048-304; 166-480-607-042-158; 179-326-554-425-927; 182-073-246-943-701,0,true,cc-by,gold -089-927-560-861-822,Affective computing scholarship and the rise of China: a view from 25 years of bibliometric data,2021-11-18,2021,journal article,Humanities and Social Sciences Communications,26629992,Springer Science and Business Media LLC,,Manh-Tung Ho; Peter Mantello; Hong-Kong T. Nguyen; Quan-Hoang Vuong,"Affective computing, also known as emotional artificial intelligence (AI), is an emerging and cutting-edge field of AI research. It draws on computer science, engineering, psychology, physiology, and neuroscience to computationally model, track, and classify human emotions and affective states. While the US once dominated the field in terms of research and citation from 1995–2015, China is now emerging as a global contender in research output, claiming second place for the most cited country from 2016–2020. This article maps the rhizomatic growth and development of scientific publications devoted to emotion-sensing AI technologies. It employs a bibliometric analysis that identifies major national contributors and international alliances in the field over the past 25 years. Contrary to the ongoing political rhetoric of a new Cold War, we argue that there are in fact vibrant AI research alliances and ongoing collaborations between the West and China, especially with the US, despite competing interests and ethical concerns. Our observations of historical data indicate two major collaborative networks: the “US/Asia-Pacific cluster” consisting of the US, China, Singapore, Japan and the “European” cluster of Germany, the UK, and the Netherlands. Our analysis also uncovers a major shift in the focus of affective computing research away from diagnosis and detection of mental illnesses to more commercially viable applications in smart city design. The discussion notes the state-of-the-art techniques such as the ensemble method of symbolic and sub-symbolic AI as well as the absence of Russia in the list of top countries for scientific output.",8,1,1,14,Psychology; China; Smart city; Scholarship; Citation; Field (Bourdieu); Cold war; Bibliometric analysis; Social science; Affective computing,,,,,https://www.nature.com/articles/s41599-021-00959-8.pdf https://econpapers.repec.org/article/palpalcom/v_3a8_3ay_3a2021_3ai_3a1_3ad_3a10.1057_5fs41599-021-00959-8.htm https://ideas.repec.org/a/pal/palcom/v8y2021i1d10.1057_s41599-021-00959-8.html https://www.nature.com/articles/s41599-021-00959-8 https://www.academia.edu/62151111/Affective_computing_scholarship_and_the_rise_of_China_a_view_from_25_years_of_bibliometric_data,http://dx.doi.org/10.1057/s41599-021-00959-8,,10.1057/s41599-021-00959-8,3213276869,,0,000-075-868-580-692; 000-096-142-707-44X; 000-818-506-502-19X; 000-819-013-664-101; 002-052-422-936-00X; 002-582-411-016-986; 003-241-487-103-606; 003-794-904-026-091; 005-124-038-616-940; 008-092-784-031-763; 008-262-579-638-864; 008-662-002-501-727; 008-860-398-187-144; 009-506-973-591-130; 009-994-264-960-189; 010-712-548-024-859; 011-581-828-016-430; 012-814-355-831-988; 013-363-927-584-924; 013-507-404-965-47X; 013-737-259-516-97X; 014-435-970-339-613; 014-454-302-531-013; 017-674-928-551-597; 018-832-955-937-265; 020-564-038-430-655; 023-998-368-315-235; 025-498-168-053-690; 031-808-580-156-243; 032-511-896-823-240; 034-768-039-318-254; 036-514-780-008-841; 036-830-310-385-532; 038-976-095-296-469; 039-070-311-342-518; 039-222-181-198-262; 040-462-098-613-443; 042-027-764-983-240; 042-463-411-537-174; 043-872-736-964-565; 054-795-280-377-647; 057-900-373-895-217; 057-967-017-369-022; 058-413-605-672-53X; 059-817-150-419-518; 059-890-787-891-431; 061-574-664-191-213; 063-502-082-845-678; 064-704-230-329-74X; 066-473-998-372-03X; 066-601-366-480-837; 073-178-067-892-119; 075-157-215-294-277; 075-578-037-587-645; 075-844-504-346-20X; 077-860-082-148-811; 079-465-962-095-167; 080-073-043-404-136; 086-868-382-140-478; 089-554-406-562-446; 089-866-000-017-395; 097-922-861-193-933; 099-088-856-834-354; 102-627-283-087-377; 103-021-691-827-063; 104-356-103-319-355; 107-518-655-388-824; 109-749-444-286-685; 111-690-344-151-52X; 111-766-450-284-957; 113-198-273-083-651; 116-895-987-060-18X; 120-243-041-147-920; 121-665-325-887-740; 122-405-276-424-453; 135-490-272-603-172; 136-923-453-367-110; 140-663-957-935-456; 141-515-257-560-448; 142-132-307-494-994; 149-039-450-187-346; 149-365-205-426-538; 151-319-008-270-751; 151-585-819-444-235; 154-170-315-871-844; 154-524-066-784-55X; 158-384-013-530-381; 166-376-952-933-293; 172-132-667-730-557; 174-236-045-984-949; 186-635-229-640-570; 191-855-602-381-278,21,true,cc-by,gold -089-952-906-576-434,The mental health of refugees in the USA: changes and the unchanged,2021-01-20,2021,journal article,Journal of Public Health,21981833; 16132238; 09431853,Springer Science and Business Media LLC,Germany,Jaisang Sun,,31,2,277,284,,,,,Syracuse University,,http://dx.doi.org/10.1007/s10389-020-01458-x,,10.1007/s10389-020-01458-x,,,0,004-559-378-182-161; 013-507-404-965-47X; 013-990-754-365-725; 021-677-147-165-755; 043-434-918-637-784; 047-134-478-431-993; 052-366-578-602-415; 122-415-544-444-960,5,false,, -090-006-054-792-069,Bibliometric Trends and Thematic Areas in Research on Cognitive Disengagement Syndrome in Children: A Comprehensive Review.,2024-01-13,2024,journal article,Research on child and adolescent psychopathology,27307174; 27307166,Springer Science and Business Media LLC,United States,Cihangir Kaçmaz; Osman Tayyar Çelik; Mehmet Sağlam; Mehmet Akif Kay; Ramazan İnci,,52,5,671,711,Scopus; Disengagement theory; Thematic analysis; Cognition; Inclusion (mineral); Psychology; Field (mathematics); Resource (disambiguation); Data science; Social science; Sociology; Qualitative research; Political science; Computer science; MEDLINE; Medicine; Gerontology; Computer network; Mathematics; Neuroscience; Pure mathematics; Law,Attention deficit hyperactivity disorder; Bibliometric analysis; Cognitive disengagement syndrome; Research trends; Sluggish cognitive tempo,"Adolescent; Child; Child, Preschool; Humans; Infant; Bibliometrics; Attention Deficit Disorder with Hyperactivity/physiopathology; Neurodevelopmental Disorders/physiopathology",,,,http://dx.doi.org/10.1007/s10802-023-01164-8,38217687,10.1007/s10802-023-01164-8,,,0,000-339-649-403-908; 000-422-715-108-665; 001-002-913-538-274; 002-802-761-932-329; 005-470-266-999-711; 007-961-340-271-390; 010-414-929-655-085; 011-039-166-543-580; 012-976-818-844-366; 013-507-404-965-47X; 013-541-969-076-695; 015-520-366-759-059; 017-266-974-653-612; 017-814-666-547-708; 020-520-403-463-160; 020-783-803-226-951; 022-066-486-456-796; 022-253-889-282-456; 022-595-540-656-072; 024-466-692-456-32X; 025-033-180-314-662; 025-755-426-729-345; 027-449-476-127-657; 029-078-069-664-108; 030-044-038-768-086; 030-683-032-253-381; 030-823-817-061-998; 031-482-108-801-360; 036-184-642-396-445; 037-614-961-116-993; 037-753-120-830-551; 038-806-520-776-446; 039-587-124-190-784; 042-285-218-025-792; 046-329-946-284-327; 046-374-334-519-669; 047-396-096-317-052; 048-981-459-894-101; 052-120-203-734-26X; 052-615-824-903-235; 052-997-643-757-116; 053-786-467-071-25X; 056-185-204-805-00X; 056-971-525-237-048; 059-335-763-907-096; 060-148-973-320-930; 060-948-504-322-971; 062-337-479-643-297; 062-550-254-605-479; 064-998-385-319-083; 068-465-868-072-154; 068-970-970-192-264; 069-343-885-011-653; 070-866-568-309-075; 070-946-209-411-828; 071-193-266-949-600; 073-760-338-998-200; 076-214-224-152-945; 076-236-750-047-819; 076-460-106-279-607; 077-857-970-643-557; 078-180-717-760-965; 078-618-760-499-487; 078-706-700-685-86X; 079-979-137-772-859; 085-386-499-131-550; 093-172-281-018-615; 094-725-163-696-179; 098-648-038-105-666; 099-761-910-083-836; 102-498-514-366-51X; 105-180-906-618-711; 108-347-685-135-265; 121-115-506-401-491; 121-229-339-038-394; 126-332-269-153-641; 131-656-957-020-844; 141-108-851-025-01X; 146-129-629-529-684; 146-289-827-774-341; 146-338-918-661-519; 148-903-448-162-695; 169-862-588-262-763; 181-448-593-725-161; 197-761-550-454-658,12,false,, -090-074-161-712-823,Impacts of epidemic outbreaks on supply chains: mapping a research agenda amid the COVID-19 pandemic through a structured literature review.,2020-06-16,2020,journal article,Annals of operations research,02545330; 15729338,Springer Science and Business Media LLC,Netherlands,Maciel M Queiroz; Dmitry Ivanov; Alexandre Dolgui; Samuel Fosso Wamba,"The coronavirus (COVID-19) outbreak shows that pandemics and epidemics can seriously wreak havoc on supply chains (SC) around the globe. Humanitarian logistics literature has extensively studied epidemic impacts; however, there exists a research gap in understanding of pandemic impacts in commercial SCs. To progress in this direction, we present a systematic analysis of the impacts of epidemic outbreaks on SCs guided by a structured literature review that collated a unique set of publications. The literature review findings suggest that influenza was the most visible epidemic outbreak reported, and that optimization of resource allocation and distribution emerged as the most popular topic. The streamlining of the literature helps us to reveal several new research tensions and novel categorizations/classifications. Most centrally, we propose a framework for operations and supply chain management at the times of COVID-19 pandemic spanning six perspectives, i.e., adaptation, digitalization, preparedness, recovery, ripple effect, and sustainability. Utilizing the outcomes of our analysis, we tease out a series of open research questions that would not be observed otherwise. Our study also emphasizes the need and offers directions to advance the literature on the impacts of the epidemic outbreaks on SCs framing a research agenda for scholars and practitioners working on this emerging research stream.",319,1,1159,1196,,Adaptation; COVID-19; Digitalization; Epidemic outbreaks; Influenza; Pandemic; Preparedness; Recovery; Resilience; Ripple effect; Structured literature review; Supply chain; Sustainability,,,,,http://dx.doi.org/10.1007/s10479-020-03685-7,32836615,10.1007/s10479-020-03685-7,,PMC7298926,0,000-735-935-494-403; 001-550-853-274-787; 003-118-998-063-278; 003-918-534-676-477; 005-249-966-849-324; 005-705-404-325-920; 005-874-710-493-866; 006-061-706-401-357; 006-974-809-924-616; 007-488-900-524-712; 007-634-717-103-525; 008-314-700-000-080; 008-759-806-128-666; 009-469-098-163-903; 010-678-247-632-774; 012-319-414-319-194; 013-507-404-965-47X; 013-569-817-215-988; 013-881-019-591-811; 014-792-234-289-828; 015-109-098-754-621; 016-162-933-848-824; 016-285-718-240-20X; 016-334-627-541-451; 017-198-861-237-805; 017-569-332-032-265; 019-292-760-096-445; 020-781-233-624-923; 021-934-975-794-244; 023-499-807-703-840; 025-614-564-772-051; 025-724-153-635-471; 027-515-122-860-635; 030-687-895-806-920; 031-294-382-849-131; 034-597-712-221-484; 034-604-011-667-152; 036-946-269-951-92X; 037-188-272-318-38X; 037-945-118-531-575; 039-308-942-349-078; 040-786-699-364-834; 044-092-999-484-87X; 046-074-652-366-472; 046-854-035-174-00X; 047-291-734-468-955; 049-345-832-077-660; 049-915-511-575-054; 050-868-037-208-260; 053-386-179-291-386; 053-675-535-273-573; 054-143-441-990-44X; 054-403-415-703-687; 054-957-936-128-82X; 056-589-710-666-111; 058-191-328-010-894; 058-985-092-989-198; 059-316-241-382-428; 060-281-746-048-351; 061-069-841-916-805; 061-217-762-898-102; 064-250-187-519-842; 065-988-334-309-683; 068-256-807-923-153; 069-079-608-898-217; 069-542-308-816-867; 069-895-676-744-362; 069-979-105-267-425; 071-678-268-538-405; 072-794-720-417-410; 073-051-524-005-610; 075-604-766-265-458; 076-482-056-870-067; 077-445-138-149-461; 077-539-064-574-170; 080-676-757-992-091; 081-844-415-501-383; 081-890-509-275-150; 082-000-903-748-912; 084-482-178-845-249; 085-300-287-100-525; 086-624-165-261-416; 087-295-767-655-668; 088-520-232-433-406; 089-385-365-445-563; 089-767-740-102-110; 089-805-325-312-262; 090-249-700-560-702; 092-416-936-225-669; 096-699-900-348-171; 096-825-169-099-35X; 096-887-073-024-939; 099-368-892-154-539; 099-911-433-850-713; 102-004-118-492-503; 107-102-389-992-092; 109-986-954-789-804; 112-406-959-820-385; 117-579-935-628-724; 119-696-527-794-630; 120-974-286-046-262; 124-964-992-107-954; 126-006-689-139-594; 127-071-086-443-527; 130-388-408-707-382; 131-478-429-199-183; 131-527-044-332-48X; 131-576-150-299-979; 133-019-034-410-159; 134-540-233-692-105; 134-898-534-776-624; 135-882-937-512-64X; 137-422-360-565-821; 142-653-891-920-30X; 151-198-090-821-824; 152-435-801-834-852; 153-017-014-360-568; 153-366-466-775-313; 157-679-895-868-174; 160-426-634-303-952; 162-150-145-696-52X; 162-483-032-793-759; 182-972-615-930-324; 183-581-238-518-032; 190-971-703-332-047,608,true,cc-by,hybrid -090-374-062-995-957,RESEARCH OF SCIENTIFIC DATA IN THE FIELD OF ARTIFICIAL INTELLIGENCE,2021-12-22,2021,journal article,System analysis and logistics,20775687,State University of Aerospace Instrumentation (SUAI),,M. S. Prokofieva,"Based on current trends, you can see the need for a deeper development of the field related to artificial intelligence. Mainly for information to minimize the occurrence of human error. Today there are many publications that confirm what was said in the above thesis. Unfortunately, it is extremely difficult to imagine the scale of interest in this topic, due to the almost complete absence of visual representations. This fact, combined with a huge amount of information, can cause difficulties not only in the study, but also in the search for materials. In this regard, there is a need for data analysis using the VOSVIEWER program, which is able to create bibliographic networks, representing the visualization of bibliographic lists, and the BIBLIOMETRIX package, which allows for quantitative analysis and statistics of articles in order to find their citation and publication activity. The analyzed materials will be downloaded from the largest bibliographic and abstract database Scopus.",4,30,57,67,Computer science; Field (mathematics); Scopus; Visualization; Data science; Information retrieval; Citation; Scale (ratio); Data visualization; Scientific literature; Information visualization; Citation analysis; Data mining; World Wide Web; MEDLINE; Cartography; Paleontology; Mathematics; Biology; Political science; Pure mathematics; Law; Geography,,,,,,http://dx.doi.org/10.31799/2077-5687-2021-4-57-67,,10.31799/2077-5687-2021-4-57-67,,,0,,0,false,, -090-638-862-568-001,An analysis of meiofauna knowledge generated by Latin American researchers,2022-11-17,2022,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Bernardo Baldeija; Diego Lercari,"Bibliographic databases used to analyse the document production of benthic meiofauna in Latin American countries. To be opened on R, bibliometrix package.",,,,,Meiobenthos; Latin Americans; Geography; Data science; Oceanography; Computer science; Geology; Philosophy; Linguistics; Benthic zone,,,,,https://zenodo.org/record/7331759,http://dx.doi.org/10.5281/zenodo.7331759,,10.5281/zenodo.7331759,,,0,,0,true,cc-by,gold -090-647-066-531-78X,The Journal of Convention and Event Tourism: A retrospective analysis using bibliometrics,2022-11-29,2022,journal article,Journal of Convention & Event Tourism,15470148; 15470156,Informa UK Limited,United States,Ranjit Singh; Sibi P. S.; Asma Bashir,"The study provides an in-depth perspective of the Journal of Convention and Event Tourism (JCET). It presents the journal’s evolution and development since 2005 by evaluating the research papers retrieved from the Scopus database. Additionally, it also shows the changing trends in MICE tourism. With the help of the Bibliometrix tool, the study analyzes and visualizes the descriptive, conceptual, social and intellectual structure of JCET. For this purpose, thematic, co-citation, and co-authorship analyses have been conducted. The results revealed that USA and Australia are the leading countries, and Fenich GG is the leading author. The following keywords appear frequently in the journal: convention, meetings, event, meeting planner, satisfaction, and convention centers. The knowledge presented in this analysis provides strategic information on scientific studies that will help researchers develop and plan their future studies in the field of event tourism.",24,1,87,108,Convention; Scopus; Tourism; Bibliometrics; Event (particle physics); Thematic analysis; Citation; Citation analysis; Thematic map; Public relations; Library science; Political science; Sociology; Social science; Computer science; Geography; Qualitative research; MEDLINE; Physics; Quantum mechanics; Cartography; Law,,,,,,http://dx.doi.org/10.1080/15470148.2022.2150731,,10.1080/15470148.2022.2150731,,,0,003-566-188-442-865; 004-279-153-318-05X; 005-228-104-008-473; 008-205-921-947-451; 009-528-652-245-031; 011-253-981-080-989; 011-383-110-980-67X; 013-507-404-965-47X; 013-524-854-219-241; 015-808-062-103-002; 019-445-640-937-523; 020-484-926-502-266; 021-194-450-733-616; 021-200-029-947-731; 022-842-421-123-463; 025-500-305-453-704; 025-855-318-734-145; 027-087-841-757-337; 028-181-888-876-381; 030-700-117-683-972; 032-239-370-293-126; 032-483-300-065-800; 032-983-548-285-955; 035-420-453-180-827; 037-839-603-835-987; 038-735-788-688-96X; 041-468-738-942-944; 042-286-047-573-886; 042-352-572-923-437; 043-658-162-928-129; 044-152-949-420-79X; 045-450-455-884-211; 045-930-899-887-547; 047-510-743-617-358; 047-937-486-942-549; 049-502-694-346-506; 051-175-108-291-124; 051-380-334-567-97X; 051-862-424-436-262; 063-653-390-776-254; 067-132-540-611-730; 068-303-293-586-530; 070-730-211-319-948; 074-339-450-461-072; 076-118-915-808-018; 079-403-401-538-243; 080-342-840-938-82X; 080-907-697-141-206; 081-268-061-227-432; 081-627-285-791-122; 086-236-128-968-725; 089-442-465-931-460; 091-606-044-169-025; 092-249-705-512-809; 093-575-552-757-636; 093-782-756-500-535; 096-267-976-700-996; 096-904-375-679-65X; 100-312-773-922-698; 103-845-103-602-493; 104-177-854-235-896; 116-046-277-377-143; 118-349-294-585-578; 120-974-286-046-262; 121-100-534-266-600; 122-037-901-208-881; 124-187-743-925-055; 133-357-674-564-473; 135-141-277-066-526; 143-930-492-945-55X; 144-669-410-085-497; 144-672-837-637-69X; 147-929-833-414-333; 149-157-958-388-920; 161-522-114-935-784; 169-039-373-756-909; 169-129-934-215-053; 173-504-571-067-261; 177-139-044-895-228; 187-357-696-543-904; 196-780-178-356-652,10,false,, -091-675-281-904-766,A bibliometric and content analysis of technological advancement applications in agricultural e-commerce,2023-01-24,2023,journal article,Electronic Commerce Research,13895753; 15729362,Springer Science and Business Media LLC,Netherlands,Hamza H. M. Altarturi; Adibi Rahiman Md Nor; Noor Ismawati Jaafar; Nor Badrul Anuar,"Given the severe difficulties and challenges being faced during the current COVID-19 pandemic, agribusinesses must consider alternative means to market and sell agriproducts using e-commerce and advanced technologies. Agricultural e-commerce that utilizes advanced technologies can promote sustainable economic growth and gender equality and, therefore, helps achieve the Sustainable Development Goals. It also allows farmers access to new markets where they can bypass intermediaries, leading to higher income, less waste, and fresher produce for customers. The usefulness of using agricultural e-commerce depends on the efficiency of addressing the emerging challenges from merging perspectives of agricultural and e-commerce fields. Literature reviews addressed both fields from different perspectives, however, most literature addresses the agriculture and e-commerce fields separately, leading to unclarity in understanding the differences between agriproducts and other products. This study aims to present a comprehensive and robust roadmap of technological advancements and challenges in agricultural e-commerce through a thorough bibliometric and content analysis and provide a conceptual architecture for best practices. The bibliometric and content analysis sheds light on the agricultural e-commerce categories, challenges, and limitations. This study identifies the most influential research and topic trends, determines the topical discipline areas, and provides visions and directions for future research in the field of agricultural e-commerce. It discusses the challenges of agricultural e-commerce and agriproducts and how advanced technologies help solve such challenges. This study summarises the best practice implementation of agricultural e-commerce by providing strong logistics, implementing standardization, including information knowledge of agriproducts, and creating a traceability information system. The result of this paper is presented as a proposed conceptual architecture for agricultural e-commerce that addresses the abovementioned best practice concepts and utilizes the Blockchain and IoT technologies to provide innovative solutions for the agricultural e-commerce stakeholders. Finally, this study provides prospects for future research on advanced technologies in agricultural e-commerce.",25,2,805,848,E-commerce; Agriculture; Intermediary; Business; Standardization; Agrochemical; Marketing; Knowledge management; Computer science; Ecology; World Wide Web; Operating system; Biology,,,,,https://link.springer.com/content/pdf/10.1007/s10660-023-09670-z.pdf https://doi.org/10.1007/s10660-023-09670-z,http://dx.doi.org/10.1007/s10660-023-09670-z,,10.1007/s10660-023-09670-z,,,0,000-002-488-651-025; 003-873-562-105-640; 005-808-597-008-447; 006-393-402-818-154; 008-092-872-335-265; 008-543-582-521-393; 008-631-831-253-896; 011-334-993-961-251; 012-107-556-969-761; 012-162-081-192-515; 013-507-404-965-47X; 013-524-854-219-241; 014-491-479-452-559; 014-660-363-332-277; 015-473-219-903-779; 017-909-560-636-325; 018-095-872-968-536; 018-788-804-105-183; 021-522-204-469-194; 024-563-601-322-137; 028-006-307-106-12X; 028-623-857-202-216; 029-420-167-353-195; 031-998-194-517-549; 033-087-543-676-464; 033-186-887-433-216; 034-304-433-459-746; 038-751-104-089-991; 039-346-483-596-033; 045-368-114-501-494; 046-189-930-084-126; 046-248-998-328-577; 046-724-127-831-016; 046-992-864-415-70X; 048-033-143-170-211; 056-406-541-298-666; 060-367-118-837-779; 061-076-248-538-933; 063-886-392-125-84X; 065-505-248-488-428; 066-711-704-793-500; 067-298-220-270-72X; 070-536-025-194-572; 071-251-371-893-621; 073-531-395-452-205; 074-023-717-184-22X; 074-359-510-202-282; 075-424-498-304-589; 077-377-846-762-732; 077-676-158-652-660; 078-113-675-394-652; 081-721-338-094-074; 084-781-479-203-303; 085-300-287-100-525; 088-284-566-232-645; 088-520-232-433-406; 092-755-067-492-162; 094-149-922-012-821; 097-616-461-294-625; 097-768-317-610-972; 099-711-542-370-376; 101-752-490-869-458; 102-491-497-598-076; 103-083-377-365-28X; 104-495-326-573-684; 107-825-944-638-084; 113-179-367-026-339; 118-817-900-085-851; 122-415-544-444-960; 125-098-245-491-970; 128-273-865-939-603; 128-656-272-846-485; 129-112-625-117-036; 130-705-982-455-630; 131-704-074-153-380; 137-538-242-672-938; 141-599-725-641-830; 146-736-407-126-85X; 147-020-780-078-123; 147-042-363-460-759; 148-020-704-916-742; 157-693-989-350-000; 163-505-340-057-316; 163-847-503-680-891; 167-329-810-640-916; 197-991-157-266-11X,16,true,,bronze -091-856-967-043-887,HIV Research Trends and Outputs Across Countries in the Eastern Mediterranean Region: A 20-Year Bibliometric Analysis (2004-2023).,2025-05-22,2025,journal article,The Journal of the Association of Nurses in AIDS Care : JANAC,15526917; 10553290,Ovid Technologies (Wolters Kluwer Health),United States,Kamiar Izadpanah; Azam Bazrafshan; Mehran Nakhaeizadeh; Hamid Sharifi,"The Eastern Mediterranean Region (EMR) faces unique challenges in addressing HIV. We conducted a bibliometric analysis of HIV research trends in the EMR (2004-2023) using the Scopus database and Bibliometrix. Among 7,162 publications identified (12.14% annual growth), five research clusters emerged, with HIV epidemiology being predominant. Research foci evolved from basic science to applied and multidisciplinary areas, with COVID-19 emerging recently. A negative, binomial, multilevel, regression model assessed relationships between country-level factors and research output. Countries with higher HIV prevalence and Human Development Index showed greater research productivity. This analysis provides insights for improving research capacity in lower-resource settings and enhancing knowledge translation across the EMR.",,,,,Scopus; Human immunodeficiency virus (HIV); Multidisciplinary approach; Geography; Productivity; Epidemiology; Tanzania; Bibliometrics; Mediterranean climate; Environmental health; Demography; Regional science; Library science; Medicine; MEDLINE; Political science; Economic growth; Social science; Sociology; Environmental planning; Family medicine; Computer science; Economics; Archaeology; Internal medicine; Law,Eastern mediterranean region; HIV; bibliometrics; research trends,,,,,http://dx.doi.org/10.1097/jnc.0000000000000558,40403039,10.1097/jnc.0000000000000558,,,0,001-306-466-248-920; 009-626-178-271-820; 010-168-316-482-221; 010-728-384-305-481; 013-524-854-219-241; 014-617-530-872-112; 025-316-943-116-761; 027-196-673-790-72X; 034-768-039-318-254; 034-993-133-281-591; 046-992-864-415-70X; 049-954-382-584-510; 060-925-854-358-809; 061-027-019-019-549; 076-773-504-022-927; 078-101-081-129-845; 078-665-922-828-469; 080-032-505-375-739; 084-669-145-601-803; 088-000-270-082-951; 090-003-691-532-004; 122-237-493-967-016; 126-886-824-954-515; 130-775-555-727-666; 161-171-977-252-573; 168-489-955-536-73X,0,false,, -091-891-734-697-576,"Sustainable Energy Research Trend: A Bibliometric Analysis Using VOSviewer, RStudio Bibliometrix, and CiteSpace Software Tools",2023-02-16,2023,journal article,Sustainability,20711050,MDPI AG,Switzerland,Abidin Kemeç; Ayşenur Tarakcıoglu Altınay,"Purpose: To systematically present the publication trends related to sustainable energy, which is an interdisciplinary concept. Design/methodology/approach: This study performed bibliometric analysis to investigate sustainable energy research between 1980 and 2022 using a sample of 1498 research papers from the Web of Science (WoS) databases, with only published articles on sustainable energy. Findings: A bibliometric analysis reveals trends in sustainable energy research publications, showing sustainable energy as an emerging topic and trends in sustainability and energy research. However, it seems that sustainable energy is still a niche area of study. Within the scope of the study, 2857 publications were included in the analysis. Of the publications included in the analysis, 1498 are articles and 1089 are other publication types. As a result of the analysis, the number of articles on the United Nations’ Sustainable Development Goals and the Paris Agreement has significantly increased since 2015. In 2022, the highest number was reached. It is seen that this finding is related to energy supply security and the reflections of geopolitical risks on it. The keyword “sustainable energy” stands out as the most frequently used keyword. Research limitations/implications: This research analysis is based on data from the Web of Science database only; there will be some shortcomings in the findings. Originality/Value: This research contributes to the field by exploring current developments in the field of sustainable energy, highlighting current gaps in the literature, and recommending future research in this field. The fact that the keywords “sustainable energy”, “renewable energy”, “sustainability”, and “sustainable development” are frequently included in the literature shows that interdisciplinary academic studies in these fields are of great importance.",15,4,3618,3618,Sustainability; Renewable energy; Sustainable energy; Originality; Bibliometrics; Sustainable development; Business; Environmental economics; Computer science; Political science; Engineering; Social science; Sociology; Economics; Library science; Ecology; Law; Electrical engineering; Biology; Qualitative research,,,,,https://www.mdpi.com/2071-1050/15/4/3618/pdf?version=1676542868 https://doi.org/10.3390/su15043618,http://dx.doi.org/10.3390/su15043618,,10.3390/su15043618,,,0,002-052-422-936-00X; 003-423-177-334-836; 005-588-363-310-297; 005-878-611-788-341; 006-360-310-128-120; 007-016-826-558-870; 010-442-924-794-711; 010-547-438-975-817; 013-507-404-965-47X; 015-359-696-187-163; 016-148-743-298-226; 017-335-491-742-553; 017-750-600-412-958; 018-276-136-448-850; 018-563-064-718-875; 026-668-072-887-856; 027-116-670-575-757; 027-881-676-096-077; 029-802-817-454-750; 030-070-985-228-781; 038-714-786-896-252; 040-841-521-740-504; 043-956-813-094-347; 044-578-745-756-214; 046-657-478-582-915; 046-992-864-415-70X; 048-441-908-889-504; 049-150-273-390-043; 050-053-442-536-172; 058-422-708-313-606; 064-697-905-538-978; 066-258-543-964-192; 066-712-125-190-144; 067-150-348-906-706; 071-042-883-844-806; 073-775-823-470-313; 074-105-780-505-072; 077-954-451-096-234; 079-966-687-925-108; 081-036-412-455-064; 082-144-953-503-211; 082-322-182-214-41X; 083-860-858-902-680; 085-001-502-383-40X; 086-461-932-456-393; 091-263-891-435-396; 092-747-946-554-630; 094-677-206-112-177; 096-871-966-641-137; 099-983-634-224-21X; 100-540-922-098-458; 102-554-620-566-922; 102-729-227-955-069; 116-339-119-777-116; 116-386-789-556-496; 123-930-404-572-031; 125-534-689-763-306; 126-464-630-137-533; 138-991-403-049-285; 142-217-786-284-734; 149-982-002-971-003; 165-451-139-230-297; 168-538-148-363-922; 187-429-053-042-102,67,true,,gold -092-199-304-213-848,Systematic Analysis of Decentralized Finance,2025-01-17,2025,journal article,Journal of Global Information Management,10627375; 15337995,IGI Global,United States,Bentzion Szrajber; Ilan Alon; Shalom Levy,"

The purpose of this article is to study analysis the Decentralized Finance (DeFi) literature. By synthesizing the themes and theorical frameworks, we aim to identify knowledge gaps and potential areas for future research in the DeFi landscape. We conduct bibliometric and content analysis on a corpus of 275 articles extracted from the Web of Science and Scopus databases. We use the Bibliometrix package in R software to apply co-citation and bibliographic coupling. We find three research clusters (a) socioeconomic (b) technology and (c) financial with their conceptual structure, interactions and transformations. Applying both co-citation and bibliographic coupling network analysis yields a dynamic view of the field tracing thematic evolution from its inception to the present day, revealing a decline in academic interest in DeFi security vulnerabilities in contrast to the growing emphasis on social media's influence on DeFi prices.

",33,1,1,29,Business; Financial system; Econometrics; Finance; Computer science; Economics,,,,,,http://dx.doi.org/10.4018/jgim.367810,,10.4018/jgim.367810,,,0,002-979-183-161-772; 003-105-137-862-171; 003-618-132-693-472; 006-528-701-354-033; 006-669-388-099-660; 007-000-236-848-476; 008-437-477-934-349; 009-318-555-715-884; 012-835-811-753-016; 013-507-404-965-47X; 015-096-850-636-51X; 015-120-970-414-548; 015-498-413-706-913; 017-750-600-412-958; 018-122-232-954-532; 019-128-299-119-244; 019-664-310-050-233; 020-566-728-906-015; 026-904-904-187-986; 027-050-501-987-321; 028-463-094-994-680; 028-466-972-983-138; 028-990-820-695-461; 035-382-904-601-72X; 036-240-096-146-329; 037-691-972-189-986; 040-774-137-038-385; 040-874-659-144-394; 041-408-191-355-951; 045-801-538-236-086; 046-377-075-194-911; 047-554-788-068-027; 047-633-884-327-397; 049-091-765-340-280; 055-562-644-328-053; 057-676-737-622-612; 064-227-180-753-26X; 066-255-797-289-410; 066-275-159-699-552; 070-131-173-483-91X; 071-730-059-626-658; 074-369-840-514-421; 074-922-663-094-825; 076-847-114-570-599; 079-454-079-817-673; 080-445-244-212-792; 084-232-189-434-507; 087-323-812-398-468; 092-902-280-111-514; 094-758-378-930-402; 098-046-700-188-833; 100-635-263-240-888; 101-178-853-976-612; 102-784-827-654-392; 103-611-480-058-540; 106-500-809-066-27X; 115-648-243-489-173; 120-577-670-924-964; 121-450-496-224-29X; 121-813-144-996-86X; 122-227-878-430-261; 123-883-232-727-631; 125-384-990-809-974; 127-374-653-320-717; 128-959-622-718-677; 129-923-036-978-996; 131-044-975-961-210; 133-442-780-103-810; 134-531-438-144-212; 134-941-798-268-595; 142-665-197-164-637; 150-300-751-438-518; 154-995-690-680-800; 155-125-925-844-820; 155-467-875-665-153; 160-290-623-654-116; 161-852-492-434-866; 163-266-451-617-421; 167-605-179-803-557; 167-820-354-860-148; 171-198-845-013-143; 171-996-452-878-169; 175-292-174-938-298; 175-356-985-065-064; 185-346-443-134-559; 187-817-906-871-565; 188-015-405-413-066; 192-630-933-696-839; 196-783-028-873-965; 199-147-698-589-789,0,true,,gold -092-307-931-399-106,Fermatean fuzzy sets and its extensions: a systematic literature review,2024-05-09,2024,journal article,Artificial Intelligence Review,15737462; 02692821,Springer Science and Business Media LLC,Netherlands,Gülçin Büyüközkan; Deniz Uztürk; Öykü Ilıcak,"AbstractThe Fermatean Fuzzy Set (FFS) theory emerges as a crucial and prevalent tool in addressing uncertainty across diverse domains. Despite its recognized utility in managing ambiguous information, recent research lacks a comprehensive analysis of key FFS areas, applications, research gaps, and outcomes. This study, conducted through the Scientific Procedures and Rationales for Systematic Literature Reviews (SPAR-4-SLR) protocol, delves into an exploration of the FFS literature, reviewing 135 relevant articles. The documents are meticulously analyzed based on their integrated methodologies, Aggregation Operators (AOs), linguistic sets, and extensions. Additionally, a thematic analysis, facilitated by the Bibliometrix tool, is presented to provide nuanced insights into future research directions and crucial areas within the literature. The study unveils valuable findings, including the integration of linguistic variables with interval-valued FFS, fostering robust environments for dynamic decision-making—a mere glimpse of the potential directions for future research. The gaps and future directions section further articulates recommendations, offering a structured foundation for researchers to enhance their understanding of FFS and chart future studies confidently.",57,6,,,Computer science; Systematic review; Management science; Set (abstract data type); Thematic map; Data science; Fuzzy set; Thematic analysis; Fuzzy logic; Key (lock); Knowledge management; Operations research; Qualitative research; Artificial intelligence; Sociology; Engineering; Social science; Political science; Geography; Cartography; Computer security; MEDLINE; Law; Programming language,,,,Galatasaray Üniversitesi,https://link.springer.com/content/pdf/10.1007/s10462-024-10761-y.pdf https://doi.org/10.1007/s10462-024-10761-y,http://dx.doi.org/10.1007/s10462-024-10761-y,,10.1007/s10462-024-10761-y,,,0,003-277-100-216-652; 003-287-772-202-850; 004-136-144-347-846; 004-264-207-747-190; 004-521-234-915-967; 005-006-940-402-077; 005-480-229-988-887; 005-487-634-243-485; 005-633-079-432-289; 006-134-884-665-675; 008-346-794-355-355; 009-751-514-788-937; 010-877-295-572-173; 011-179-547-741-112; 012-977-974-727-836; 013-507-404-965-47X; 015-945-078-873-15X; 017-632-749-626-13X; 018-248-452-194-698; 019-954-948-108-41X; 019-968-145-374-471; 019-998-209-230-491; 022-077-385-481-013; 025-315-597-239-798; 025-430-252-645-153; 025-819-602-878-850; 026-775-270-013-045; 027-471-484-920-04X; 027-754-786-584-475; 028-196-499-204-866; 028-497-697-289-353; 028-680-742-516-443; 028-963-781-718-515; 029-163-090-736-125; 030-028-261-001-507; 030-144-076-128-221; 030-222-024-954-696; 030-619-346-789-73X; 032-488-477-546-442; 032-767-602-272-543; 033-254-271-106-972; 033-797-482-651-832; 033-936-535-459-965; 034-291-720-211-532; 034-507-260-320-980; 034-842-182-246-006; 034-911-374-699-524; 035-515-706-014-176; 036-333-820-768-085; 036-400-562-334-352; 036-617-362-362-567; 036-657-520-728-760; 037-423-792-391-123; 039-095-439-286-923; 040-121-455-329-905; 040-421-578-005-278; 041-389-092-874-43X; 041-397-429-198-626; 042-477-379-794-142; 044-270-805-328-692; 044-779-725-184-651; 044-782-509-606-60X; 048-358-881-696-878; 050-919-902-508-717; 051-061-492-392-601; 051-238-798-834-928; 051-374-317-696-031; 052-154-841-646-999; 052-659-385-350-804; 052-686-990-735-60X; 053-978-676-821-551; 054-161-388-612-528; 056-449-245-993-920; 056-565-499-638-468; 056-870-325-221-989; 057-066-687-652-54X; 057-161-654-134-901; 058-134-133-444-966; 058-889-947-817-608; 060-395-077-875-311; 061-113-044-396-566; 065-739-386-731-82X; 067-278-165-089-179; 067-568-814-948-558; 068-313-378-288-283; 068-698-838-187-767; 070-037-254-844-579; 071-852-134-495-965; 072-081-972-633-523; 072-187-718-665-314; 073-143-473-596-382; 074-429-539-183-995; 075-395-976-303-661; 076-279-189-469-37X; 078-108-653-565-08X; 078-587-047-989-959; 078-627-394-872-37X; 078-801-081-679-000; 079-692-259-232-676; 082-435-115-229-786; 082-708-765-000-984; 085-100-231-901-175; 086-868-889-454-812; 086-897-486-850-194; 087-610-916-333-871; 088-443-729-586-049; 088-835-120-653-224; 089-652-019-106-896; 090-512-186-794-981; 092-140-577-346-244; 092-606-696-182-483; 096-538-274-286-999; 097-497-535-193-079; 097-671-360-317-498; 097-942-624-961-757; 098-377-249-596-555; 098-393-963-328-355; 099-572-383-118-642; 100-680-832-013-320; 100-832-866-452-719; 103-332-265-468-916; 104-124-358-414-490; 104-507-330-220-983; 106-050-610-195-861; 106-828-770-866-518; 110-055-043-417-890; 113-682-442-621-962; 115-441-660-911-058; 115-930-360-441-469; 120-631-201-622-44X; 123-491-756-931-251; 123-714-533-506-149; 125-972-694-245-271; 127-471-798-585-024; 128-177-500-561-943; 128-458-262-324-90X; 132-681-562-588-460; 134-243-323-187-224; 138-150-982-862-396; 139-121-904-111-902; 139-247-301-090-886; 140-979-993-584-084; 141-227-802-282-484; 144-333-034-397-606; 145-950-612-027-421; 145-967-685-247-573; 146-522-018-118-828; 147-310-829-762-15X; 147-719-248-268-907; 148-237-994-348-532; 148-238-150-384-677; 150-567-590-296-709; 155-848-446-835-088; 155-895-106-790-727; 157-189-310-438-100; 158-873-269-950-678; 158-938-291-902-730; 160-044-866-105-900; 160-700-902-657-810; 164-701-325-171-182; 167-071-982-661-54X; 169-041-612-300-945; 169-477-436-031-594; 169-497-758-664-624; 169-765-577-258-588; 170-746-094-014-361; 171-289-078-311-716; 171-573-103-970-851; 171-765-935-706-89X; 173-634-852-362-836; 175-256-014-829-06X; 181-317-854-637-187; 182-323-503-367-143; 182-728-227-308-782; 186-072-983-454-175; 186-209-789-961-151; 187-563-286-573-067; 188-368-994-076-769; 192-199-855-418-749; 193-675-427-604-298; 194-747-116-391-009; 196-120-751-394-51X; 199-013-687-430-402,13,true,cc-by,hybrid -092-412-650-490-979,Inteligência Artificial na auditoria de recursos públicos: análise bibliométrica via software Bibliometrix,2025-04-28,2025,journal article,CONTRIBUCIONES A LAS CIENCIAS SOCIALES,19887833,Brazilian Journals,,Luciana Fabiano; Marlene Valerio dos Santos Arenas; Valmir Batista Prestes de Souza,"O exíguo tempo existente entre as recentes e significativas alterações na área de inteligência artificial (IA), pautadas no modelo ChatGPT, com a utilização de grandes modelos de linguagem digital, large language model (LLM), relacionadas ao aprendizado de máquina, machine learning, dificulta a tomada de conhecimento sobre as consequências dessa inovação. Essa conjuntura aplicada aos órgãos públicos configura grande preocupação devido à adesão em larga escala por inúmeras instituições em diferentes partes do mundo. O crescente uso da IA em auditorias de órgãos públicos, na área de controle externo, é um exemplo desse cenário. Pesquisas acerca dos resultados advindos do uso indiscriminado da IA no setor público precisam ser ponderadas. O objetivo deste estudo foi mapear a literatura científica sobre a aplicação da IA no controle externo, com foco em atividades de auditorias governamentais de recursos públicos, em âmbito nacional e internacional. A pesquisa integra os Objetivos de Desenvolvimento Sustentáveis (ODS) nº 9 - Indústria, Inovação e Infraestrutura. As análises foram desenvolvidas por meio do método bibliométrico tratando os metadados via software Bibliometrix. Os resultados mostraram um mapa-múndi da dinâmica internacional dessa literatura, os autores e países mais produtivos e uma tendência a linhas de pesquisa sobre a “qualidade” da IA. Concluiu pelo predomínio do segmento teórico sobre “sistemas”.",18,4,e17373,e17373,Physics,,,,,,http://dx.doi.org/10.55905/revconv.18n.4-318,,10.55905/revconv.18n.4-318,,,0,,0,false,, -092-632-961-587-22X,Comprehending the Multifaceted Realm of Blockchain Within the Hotel Industry,2024-08-16,2024,book chapter,"Advances in Hospitality, Tourism, and the Services Industry",24756547; 24756555,IGI Global,,Dilip Kumar; Abhinav Kumar Shandilya; Nishikant Kumar,"To identify the performance pattern, keyword cluster appearance and thematic development of blockchain adoption in the hotel industry from the literature published in the Scopus database since 2018. The PRISMA pattern was followed for the inclusion and exclusion of data. The data was extracted from the Scopus database since 2018. Initially, 93 data appeared in the search and after refining the dataset bibliometric analysis was performed for 48 documents. Bibliometrix (Biblioshiny), an open-access software, was used to analyse the data. The keyword clusters that appeared are “Luxury augmented experiences”, “Experiential hospitality”, “Decentralised hospitality solutions”, and “Secure AI ecosystem”. Bibliographic coupling analysis (BCA) generated four major themes - “Impact of technologies in hospitality and tourism”, “Technological transformation in hotels”, “Bitcoin and blockchain in hotels”, and “Security solutions and blockchain”. The adoption of blockchain technology can play a pivotal role in achieving the Sustainable Development Goals – 9.",,,203,218,Blockchain; Realm; Business; Computer science; Computer security; Geography; Archaeology,,,,,,http://dx.doi.org/10.4018/979-8-3693-7898-4.ch010,,10.4018/979-8-3693-7898-4.ch010,,,0,000-273-025-171-011; 001-774-743-466-254; 005-440-673-215-622; 008-398-062-467-735; 013-507-404-965-47X; 013-524-854-219-241; 015-075-023-392-467; 027-713-117-828-777; 033-700-785-279-026; 040-358-685-489-600; 051-647-739-244-271; 065-010-405-236-060; 065-962-476-626-662; 072-979-681-847-477; 073-545-316-581-71X; 075-820-476-512-461; 076-219-389-310-879; 077-222-886-075-965; 084-482-215-025-54X; 093-218-840-885-661; 093-951-371-004-180; 099-836-228-217-030; 100-560-294-392-119; 100-603-573-401-580; 107-555-945-932-560; 118-196-061-328-998; 120-968-113-552-705; 121-827-751-123-988; 147-673-689-593-616; 150-729-682-048-410; 152-682-071-174-079; 156-713-343-222-826; 159-353-331-775-792; 178-652-207-146-007; 193-209-082-859-317,0,false,, -093-053-790-849-589,OS IMPACTOS DO TRABALHO REMOTO SOBRE A QUALIDADE DE VIDA NO TRABALHO EM TEMPOS DE COVID-19: ESTUDO DE CASO COM DOCENTES DO ENSINO MÉDIO,,2022,journal article,Revista SODEBRAS,18093957,Revista SODEBRAS,,R. S. Cardoso; M. R. Maduro; E. P. Teixeira; M. A. Bittencourt,"The professional nurse, when dealing with a patient, often experiences adverse situations in their work environment. This can affect their health. In order to know about this daily life, the present study aimed to carry out a bibliometric analysis on the theme Burnout in nurses where, in a more punctual way, we sought to identify the main predictors of Burnout of this profession from recent international publications. In the first part of the study, the software R (bibliometrix package) was used. Burnout predictors were identified from the articles resulting from the bibliometric search. The survey results pointed to an increase in publications over the years with a peak in 2018. The largest contributions in quantitative terms are still from the United States of America. Burnout predictors have an organizational and relational origin. Individual aspects, such as resilience, appear in a relevant way to avoid professional illness.",17,197,32,47,Humanities; Coronavirus disease 2019 (COVID-19); Philosophy; Medicine; Disease; Pathology; Infectious disease (medical specialty),,,,,,http://dx.doi.org/10.29367/issn.1809-3957.17.2022.197.32,,10.29367/issn.1809-3957.17.2022.197.32,,,0,,0,true,,gold -093-318-324-414-052,Decoding the Future of Omnichannel Retailing: A Science Mapping Analysis with Bibliometrix,2024-06-30,2024,journal article,Commerce & Business Researcher,09764097,"Researchers' Forum, Department of Commerce, University of Kerala, Karyavattom",,Sumi J; Priya R,"Omnichannel retailing is a vital research area that has gained wide popularity in this e-business world. It is the retailing that provides customers with a seamless shopping experience through both physical and digital channel integration. This paper tries to examine the established information regarding the Omnichannel retailing strategy and offers future research directions. We obtained data from the Scopus database and presented a bibliographic overview of the research on Omnichannel retailing. To investigate and analyse the main discoveries regarding the collection, we performed a five-stage mapping study. The result shows that the research field has grown significantly over the last ten years, and the USA is the most productive nation in all aspects. The findings reveal that Omnichannel retailing has grown considerably, concentrating on themes like customer journey design, digital convergence, and the integration of both online and offline platforms. The study also suggests that future research should focus on addressing issues such as the practical implementation of technology advancements, sustainability in retail ecosystems, the role of consumers in the hybrid mode shopping channels, the impact of artificial intelligence, large-scale personalization, etc. Therefore, this academic research has an informational role that depicts the most fundamental area of this e-retailing world.",16,1,79,101,Omnichannel; Decoding methods; Computer science; Telecommunications; World Wide Web,,,,,,http://dx.doi.org/10.59640/cbr.v16i1.79-101,,10.59640/cbr.v16i1.79-101,,,0,,0,false,, -093-511-210-481-972,"Governance, management, sustainability, and performance in the football industry: A bibliometric analysis",,2024,journal article,CORPORATE GOVERNANCE AND RESEARCH & DEVELOPMENT STUDIES,27048462; 27239098,Franco Angeli,,Carmen Gallucci; Riccardo Tipaldi,"This paper utilizes the bibliometrix R package for a bibliometric analysis of 572 academic documents spanning from 1992 to 2023. These documents, sourced from 213 scholarly outlets via the Web of Science Database, focus on the governance, management, sustainability, and performance of football clubs. The analysis marks significant developments in this field, examines the interplay among various research topics, and quantifies the contributions from journals, authors, and countries. Furthermore, it outlines several potential avenues for future research. The results emphasize the interconnection of governance, management, sustainability, and performance within football clubs.",,1,101,129,Corporate governance; Football; Sustainability; Business; Bibliometrics; Accounting; Political science; Computer science; Library science; Finance; Ecology; Law; Biology,,,,,,http://dx.doi.org/10.3280/cgrds1-2024oa16958,,10.3280/cgrds1-2024oa16958,,,0,002-304-688-263-912; 002-454-665-043-70X; 005-479-042-606-799; 008-155-335-331-379; 008-191-565-399-086; 009-901-983-414-904; 011-239-746-039-897; 012-156-499-820-776; 012-950-457-954-539; 013-507-404-965-47X; 015-638-539-772-758; 015-680-686-465-79X; 017-355-820-932-509; 017-750-600-412-958; 018-558-594-513-803; 022-139-266-848-354; 022-232-506-655-698; 027-238-035-697-478; 030-855-542-727-960; 032-901-568-799-046; 033-822-520-351-147; 034-339-421-939-443; 034-514-815-960-822; 035-406-347-409-025; 036-595-544-848-168; 036-665-626-934-925; 045-085-272-792-303; 045-386-163-096-48X; 045-961-475-607-195; 046-320-196-689-307; 046-992-864-415-70X; 052-411-054-952-115; 058-269-831-826-804; 060-234-276-892-678; 064-018-821-359-019; 066-208-207-980-008; 068-471-312-923-655; 071-915-992-424-886; 073-005-917-411-591; 074-689-637-760-304; 075-747-769-660-339; 076-132-916-208-314; 081-333-726-078-805; 085-764-420-535-049; 087-898-296-565-844; 090-523-909-566-629; 094-164-804-385-673; 095-094-364-771-305; 098-122-551-015-120; 101-288-603-975-876; 102-037-134-351-920; 105-699-604-274-803; 106-790-882-771-037; 106-985-318-207-654; 110-892-442-747-668; 114-352-973-897-348; 115-491-461-797-42X; 115-979-310-992-542; 117-710-309-495-726; 119-520-519-786-519; 120-472-071-678-49X; 124-636-316-269-293; 153-494-566-213-39X; 154-767-167-795-342; 158-859-446-371-415; 176-346-326-759-975; 179-624-827-984-026; 198-296-884-957-912,0,false,, -094-047-955-399-199,"Mapping breast cancer research on monoclonal antibodies: a data-driven approach using VOSviewer, Bibliometrix, and CiteSpace",2025-06-25,2025,journal article,Naunyn-Schmiedeberg's Archives of Pharmacology,00281298; 14321912,Springer Science and Business Media LLC,Germany,Siddig Ibrahim Abdelwahab; Sivakumar S. Moni; Manal Mohamed Elhassan Taha; Khaled A. Sahli; Hatem Ahmed Salem Alqhtani; Moath Mohamed Farasani; Marwa Qadri; Abdulaziz Alarifi; Amani Khardali; Khulud Hamoud Alsaadi; Abdullah Farasani; Nizar A. Khamjan; Humaid Al-shamsi; Jobran M. Moshi; Saeed Alshahrani; Ahmed Salawi; Ahmad Assiri; Ayah Ibrahim,,,,,,,,,,,,http://dx.doi.org/10.1007/s00210-025-04401-7,,10.1007/s00210-025-04401-7,,,0,000-032-742-203-955; 002-052-422-936-00X; 004-024-643-541-524; 004-614-692-603-824; 005-482-910-898-996; 007-941-395-122-829; 008-972-686-737-768; 009-673-635-454-182; 013-420-137-949-018; 013-507-404-965-47X; 016-639-926-389-40X; 017-224-400-020-511; 018-602-442-790-241; 026-470-399-924-758; 030-681-154-009-37X; 031-079-674-450-200; 031-911-895-455-956; 033-185-570-423-103; 036-438-381-267-668; 036-933-730-278-698; 037-576-282-115-505; 040-990-392-690-182; 041-183-580-514-499; 041-413-300-627-036; 052-116-663-989-544; 052-497-824-938-660; 052-858-154-849-845; 052-873-430-604-154; 055-928-547-951-525; 056-513-159-268-160; 059-181-827-646-78X; 062-392-645-313-421; 063-408-271-032-86X; 063-688-453-610-631; 064-073-267-069-621; 064-400-499-357-900; 066-144-381-016-628; 068-709-862-533-085; 069-497-967-323-628; 071-878-836-294-733; 074-270-403-692-764; 074-724-021-924-48X; 075-227-483-465-758; 076-498-170-063-038; 082-663-835-495-884; 086-861-409-197-465; 088-859-524-434-761; 089-387-315-260-607; 092-591-963-854-258; 095-145-318-401-108; 107-483-302-885-238; 114-153-318-228-330; 116-777-905-421-010; 120-946-208-461-921; 122-827-252-276-011; 123-528-484-887-707; 131-020-931-370-56X; 141-153-710-654-624; 141-372-970-264-032; 146-775-655-168-903; 149-024-740-298-675; 152-441-477-865-032; 156-384-098-893-807; 157-418-078-755-334; 163-563-585-153-870; 169-887-307-605-354; 170-277-299-877-903; 174-517-546-129-466; 187-289-965-100-721; 192-240-678-319-855; 196-804-064-842-904,0,false,, -094-103-682-424-654,"Silent battles, global insights: anxiety and depression in the world of assisted reproduction.",2025-02-28,2025,journal article,Journal of assisted reproduction and genetics,15737330; 10580468; 07407769,Springer Science and Business Media LLC,United States,Yongjia Zhou; Qingyong Zheng; Caihua Xu; Yiyi Li; Tengfei Li; Lin Li; Li Wang; Jinhui Tian; Guangmei Xie,,42,4,1317,1329,Reproductive medicine; Anxiety; Reproduction; Depression (economics); Human reproduction; Psychiatry; Psychology; Medicine; Biology; Pregnancy; Genetics; Macroeconomics; Economics,Anxiety; Assisted reproductive technology; Bibliometric analysis; Depression,"Humans; Reproductive Techniques, Assisted/psychology; Anxiety/epidemiology; Depression/epidemiology; Female; Infertility/psychology",,,,http://dx.doi.org/10.1007/s10815-025-03422-8,40019701,10.1007/s10815-025-03422-8,,PMC12055705,0,000-270-380-125-69X; 002-110-391-524-194; 005-723-834-500-951; 011-955-381-695-687; 011-986-494-303-020; 012-018-542-809-949; 013-507-404-965-47X; 016-965-806-097-166; 017-006-504-782-603; 017-275-742-246-238; 019-025-156-375-425; 019-938-578-889-975; 026-649-274-502-64X; 027-483-992-830-604; 047-423-445-536-853; 049-560-744-851-187; 050-858-163-515-254; 061-207-025-121-644; 072-855-254-952-059; 082-482-667-175-554; 089-240-538-648-063; 094-754-973-880-931; 095-258-727-198-201; 101-704-167-220-636; 116-186-375-364-009; 117-906-685-804-689; 127-220-952-215-35X; 129-813-016-422-029; 131-283-705-757-330; 131-871-332-911-024; 152-754-044-269-961; 156-177-730-419-497; 163-808-722-220-842; 189-382-004-563-62X; 196-040-214-382-011,0,false,, -094-263-700-954-249,Unveiling scientific integrity in scholarly publications: a bibliometric approach,2024-10-07,2024,journal article,International Journal for Educational Integrity,18332595,Springer Science and Business Media LLC,,Lan Thi Nguyen; Kulthida Tuamsuk,"Scientific integrity stands as a fundamental principle and benchmark for the conduct of research and the dissemination of scholarly content. The objective of this research aims to explore the impact of research, new and emerging areas of research, and to identify potential research collaborators and journals of scientific integrity for scholarly publishing over the last 20 years. Utilizing data sourced from the Scopus database, this research gathers publications linked to scientific integrity in scholarly publishing spanning from 2004 to 2023. These records were subjected to bibliometric analysis through Bibliometrix and VOSviewer. The findings indicate that research articles are the predominant mode of publication, constituting a substantial 67.27% of the total. Moreover, this content has been contributed by a diverse group of 2,596 authors. The Journal of Science and Engineering Ethics distinguishes itself with an outstanding record of publishing 62 articles and an impressive H-index of 19. The USA possesses the most extensive collaborative network, followed by Australia and the United Kingdom. Another significant discovery from this research underscores that over 20 years, dominant research trends have revolved around topics concerning scientific integrity, such as academic integrity, research integrity, and research misconduct.",20,1,,,Scientific integrity; Bibliometrics; Research integrity; Political science; Data science; Library science; Engineering ethics; Computer science; Engineering,,,,,,http://dx.doi.org/10.1007/s40979-024-00164-5,,10.1007/s40979-024-00164-5,,,0,001-986-861-996-939; 005-338-053-226-75X; 010-189-518-627-284; 013-507-404-965-47X; 022-226-436-475-710; 023-780-524-116-27X; 025-439-278-529-012; 030-828-605-079-259; 032-061-464-112-335; 033-803-564-840-467; 033-820-479-676-230; 034-834-076-315-610; 038-958-053-088-785; 042-698-192-538-316; 046-992-864-415-70X; 054-216-721-313-691; 054-304-687-871-197; 058-211-874-316-95X; 060-403-754-313-322; 077-809-453-774-19X; 078-768-968-526-409; 087-001-228-297-068; 087-028-575-608-633; 088-554-719-960-000; 105-134-794-523-656; 115-481-548-529-648; 124-902-227-805-145; 139-025-371-510-74X; 146-208-436-691-12X; 153-108-877-433-279; 153-594-935-343-308; 158-212-236-237-720; 167-758-630-424-808; 174-404-294-752-460; 181-077-528-752-104; 188-859-720-720-007; 193-288-095-119-05X; 193-511-600-603-467,3,true,"CC BY, CC0",gold -094-460-921-253-895,"Bibliometric analysis of individual carbon neutrality reasearch: hotspots, dominant themes and evolutionary trends",2024-10-09,2024,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Lifang Fu; Xinru Bian; Banxiang Chu,,,,,,Neutrality; Sustainable development; Geography; Political science; Biology; Ecology; Law,,,,General Project of Philosophy and Social Science of Heilongjiang Province,,http://dx.doi.org/10.1007/s10668-024-05509-1,,10.1007/s10668-024-05509-1,,,0,000-848-264-004-813; 001-300-724-036-73X; 001-314-314-598-462; 002-823-045-983-144; 002-914-403-134-833; 003-328-316-204-084; 005-960-385-831-702; 007-016-826-558-870; 008-477-439-776-091; 008-630-341-756-357; 009-610-682-517-029; 009-791-731-810-391; 010-395-681-660-540; 011-031-322-868-170; 011-533-719-625-054; 011-998-209-246-353; 016-379-263-010-260; 018-546-770-900-995; 020-864-347-974-001; 021-279-413-971-204; 022-824-786-189-079; 022-908-812-720-555; 023-069-533-937-614; 025-275-349-898-272; 025-579-023-813-008; 026-779-469-943-555; 027-098-816-612-412; 027-354-298-886-762; 028-425-331-477-859; 031-187-002-607-584; 034-770-446-785-282; 036-309-819-891-561; 037-677-933-704-761; 038-020-458-368-112; 043-811-763-053-303; 046-122-763-775-731; 046-356-310-680-627; 048-738-890-999-509; 049-516-775-098-361; 050-870-604-072-607; 050-930-396-988-670; 052-140-118-036-035; 054-656-111-759-249; 055-526-323-091-640; 060-062-399-404-437; 060-219-857-468-407; 061-020-965-050-25X; 063-076-777-551-984; 063-168-967-412-123; 063-244-127-908-128; 064-400-499-357-900; 065-812-557-404-451; 067-565-431-298-005; 068-232-408-719-669; 069-477-897-519-706; 069-811-193-422-886; 070-464-333-845-47X; 071-223-246-664-32X; 072-708-269-512-160; 074-319-009-294-05X; 074-590-959-363-90X; 075-743-099-591-726; 076-354-130-237-168; 077-743-568-492-572; 079-152-716-973-57X; 079-537-736-306-042; 079-540-855-767-404; 081-672-886-346-780; 083-595-901-813-487; 087-479-876-991-587; 088-513-342-096-679; 089-170-438-746-693; 093-927-137-955-674; 094-723-638-452-815; 095-329-437-218-898; 097-098-960-848-891; 097-875-158-386-515; 099-887-087-151-794; 108-342-180-147-778; 109-536-864-676-883; 111-723-986-200-504; 113-645-946-775-735; 114-352-973-897-348; 114-368-494-085-39X; 115-194-489-276-844; 116-741-278-289-06X; 117-349-034-417-547; 118-139-302-027-547; 118-157-682-560-309; 118-524-172-865-614; 120-460-224-392-081; 121-273-737-773-376; 131-096-655-720-674; 131-528-494-809-403; 133-665-917-316-699; 135-183-405-471-127; 137-092-220-677-048; 139-623-997-989-860; 141-162-596-743-985; 144-921-923-856-471; 146-340-710-814-806; 159-105-594-520-262; 160-029-443-401-059; 160-351-817-840-298; 161-871-899-672-94X; 165-830-084-790-261; 173-743-695-356-418; 174-469-947-806-276; 175-840-003-283-711; 179-279-576-773-077; 181-567-287-560-41X; 186-591-706-278-921; 192-986-092-646-083; 194-082-809-144-20X; 199-731-497-573-409,0,false,, -094-538-342-483-028,"MACHINING BY CHIP REMOVAL: BIBLIOMETRIC ANALYSIS, EVOLUTION, AND RESEARCH TRENDS",2022-06-30,2022,journal article,Journal of Southwest Jiaotong University,02582724,Southwest Jiaotong University,China,Diana Carolina Gálvez Coy; Pablo Andres Erazo Muñoz; Fernando Londoño Zapata; John Alexander Ortiz Torres; Carloman Arcila Zuluaga,"This paper aims to acquaint the readers with the research trends in the area of machining by chip removal, which has been widely used as a process of component manufacturing in industry, through bibliometric analysis. In this paper, the review and the network analysis were obtained by tools such as Bibliometrix in R, VOSviewer, Sci2, and Gephi to identify the tree of science of the literature related to machining by chip removal. This review identified four main lines or clusters related to modeling of machining processes, machining processes, machining fluids, and machining surface monitoring. This allows teachers, researchers, and academicians interested in the topic to know its evolution and trends to guide subsequent research.",57,3,336,346,Machining; Chip; Process (computing); Manufacturing engineering; Bibliometrics; Chip formation; Computer science; Engineering; Mechanical engineering; Tool wear; Data mining; Telecommunications; Operating system,,,,,https://www.jsju.org/index.php/journal/article/download/1253/1243 https://doi.org/10.35741/issn.0258-2724.57.3.27,http://dx.doi.org/10.35741/issn.0258-2724.57.3.27,,10.35741/issn.0258-2724.57.3.27,,,0,,0,true,,bronze -094-705-363-195-450,Neurodevelopmental disorders and family quality of life: emerging trends and future research directions.,2024-06-26,2024,journal article,Pediatric research,15300447; 00313998,Springer Science and Business Media LLC,United States,Dunia Garrido; Andrés Catena; Rocio Garcia-Retamero,,97,1,107,114,Scopus; Autism spectrum disorder; Psychology; Attention deficit hyperactivity disorder; Quality of life (healthcare); Web of science; Neurodevelopmental disorder; Thematic analysis; Clinical psychology; Autism; Psychiatry; MEDLINE; Developmental psychology; Medicine; Meta-analysis; Qualitative research; Psychotherapist; Social science; Sociology; Political science; Internal medicine; Law,,Neurodevelopmental Disorders/psychology; Autism Spectrum Disorder/psychology; Attention Deficit Disorder with Hyperactivity/psychology; Humans; Male; Female; Child; Adolescent; Adult; Family Health; Quality of Life/psychology; Young Adult; Family/psychology; Biomedical Research/trends,,,,http://dx.doi.org/10.1038/s41390-024-03350-w,38926550,10.1038/s41390-024-03350-w,,,0,003-513-453-440-707; 003-527-971-174-979; 004-294-864-386-492; 007-494-656-792-483; 007-870-406-589-729; 010-579-560-048-730; 013-507-404-965-47X; 013-524-854-219-241; 016-464-449-717-172; 019-079-163-569-635; 019-643-564-761-438; 019-704-491-230-658; 019-925-982-604-49X; 021-907-568-054-165; 025-313-686-583-188; 028-068-231-256-482; 028-579-281-829-730; 029-135-609-901-089; 029-991-640-756-977; 031-435-085-672-487; 031-782-194-721-707; 034-145-218-792-807; 038-124-125-506-763; 038-778-011-674-913; 043-153-504-628-940; 044-538-402-680-223; 045-112-521-636-151; 045-368-114-501-494; 047-371-413-205-505; 048-708-416-622-168; 049-168-397-271-359; 051-691-882-155-421; 052-504-878-705-400; 053-167-428-176-259; 055-494-988-809-692; 059-066-414-441-424; 061-817-580-470-016; 062-247-787-610-834; 065-010-405-236-060; 067-059-801-677-773; 069-552-634-797-138; 069-571-498-103-325; 077-156-228-356-906; 077-480-163-806-586; 078-408-396-562-99X; 080-468-990-568-100; 082-352-545-881-236; 098-869-451-628-419; 098-947-305-289-173; 103-768-904-869-220; 106-301-603-995-119; 113-147-632-013-226; 121-115-506-401-491; 121-152-968-213-455; 127-580-965-644-427; 131-423-542-523-282; 141-395-635-042-565; 147-330-789-818-398; 159-382-288-612-420; 175-851-555-983-875,0,false,, -094-887-835-247-600,Recent Applications and Developments of the Cobb–Douglas Function: From Productivity to Sustainability,2024-05-16,2024,journal article,Journal of the Knowledge Economy,18687873; 18687865,Springer Science and Business Media LLC,Germany,Cristian Colther; Jean Pierre Doussoulin,,16,1,1646,1666,CobB; Sustainability; Entrepreneurship; Productivity; Cobb–Douglas production function; Function (biology); Economics; Natural resource economics; Industrial organization; Business; Production (economics); Economic growth; Microeconomics; Ecology; Finance; Genetics; Evolutionary biology; Biology,,,,,,http://dx.doi.org/10.1007/s13132-024-02061-1,,10.1007/s13132-024-02061-1,,,0,000-412-657-316-976; 000-848-264-004-813; 005-015-566-349-847; 005-775-759-991-299; 008-168-448-758-144; 008-227-012-268-686; 012-716-414-162-990; 012-956-291-277-992; 013-507-404-965-47X; 015-502-583-624-493; 020-750-501-347-722; 022-146-901-159-378; 023-652-955-003-406; 025-376-384-314-984; 028-037-650-718-395; 030-687-198-866-805; 030-942-732-879-821; 032-166-845-968-20X; 034-400-650-596-667; 044-418-516-567-986; 049-391-379-302-694; 051-358-504-917-418; 067-046-675-301-851; 080-070-134-688-580; 083-484-126-965-401; 093-586-103-723-098; 094-067-438-735-770; 100-567-893-154-579; 110-916-817-987-232; 117-177-941-034-146; 122-827-252-276-011; 130-037-465-901-857; 132-755-098-458-222; 137-893-534-387-81X; 143-517-196-654-409; 150-672-810-080-825; 162-420-019-124-341; 175-511-485-871-016,2,false,, -094-952-443-905-422,Bibliometrics analysis and knowledge mapping of pertussis vaccine research: trends from 1994 to 2023.,2024-10-17,2024,journal article,Infection,14390973; 03008126,Springer Science and Business Media LLC,Germany,Caixia Tan; Yuanyuan Xiao; Siyao Chen; Ting Liu; Juan Zhou; Sisi Zhang; Yiran Hu; Jingxiang Zhou; Zhongyan She; Biyue Tian; Anhua Wu; Chunhui Li,"This study aims to use bibliometric methods to explore the evolving landscape, hotspots, and emerging frontiers of pertussis vaccine research, providing deeper insights into the current research landscape and guiding future vaccine development efforts.; We conducted a comprehensive search of the Web of Science Core Collection database (WoSCC) from January 1, 1994, to December 31, 2023, employing search terms related to vaccination (vacc* or immun*) and pertussis (pertussis, Whooping Cough, Bordetella pertussis, B. pertussis, Bordetella pertussis infection, or B. pertussis infection) in the Title or Author keywords fields. Bibliometrics analysis of pertussis research was performed utilizing the bibliometrix-biblioshiny package in RStudio, alongside CiteSpace and VOSviewer software.; In total, 2,623 records were analyzed, comprising 89.63% (n = 2,351) original research articles and 10.37% (n = 272) review articles. The study revealed that academic research on the pertussis vaccine was growing at a rate of 4.64% per year. The United States and Canada lead in the number of publications. GlaxoSmithKline and the Centers for Disease Control & Prevention- United States emerged as leading institutions, with Halperin SA and Locht C as the most active authors. Vaccine was the most influential journal. Most studies focused on vaccine effectiveness duration, vaccination schedules for high-risk groups, and people's attitudes toward vaccination.; Our analysis showed increasing interest of researchers in pertussis literature, yet current research mainly emphasized expanding vaccine coverage and optimizing strategies, neglecting new vaccine development. This emphasized the need for prioritizing novel pertussis vaccines to tackle the resurgence challenge.; © 2024. The Author(s).",53,3,1001,1012,Bibliometrics; Bordetella pertussis; Whooping cough; Medicine; Geography; Virology; Library science; Vaccination; Biology; Computer science; Genetics; Bacteria,Bibliometrics; Immunogenicity; Infants; Pertussis; Vaccine,Bibliometrics; Pertussis Vaccine/immunology; Humans; Whooping Cough/prevention & control; Biomedical Research/trends; Vaccination,Pertussis Vaccine,"National Key Research and Development Program of China (2022YFC2009801); National Key Research and Development Program of China (2022YFC2009805); Project program of National Clinical Research Center for Geriatric Disorders (Xiangya Hospital) (2021KFJJ05); Natural Science Foundation of Hunan Province (2021JJ31071); Health Development Research Center of the National Health Commission, ""Evidence-based Evaluation and Demonstration Base Construction Project of Infection Control Measures in Healthcare Institutions (CNHDRC-KJ-L-2020-53-04375); Scientific and technological personnel lifting Project in Hunan Province (2023TJ-Z11)",,http://dx.doi.org/10.1007/s15010-024-02414-7,39417957,10.1007/s15010-024-02414-7,,PMC12137378,0,002-052-422-936-00X; 005-423-035-888-799; 005-461-749-456-565; 006-743-709-219-102; 010-341-201-079-033; 012-839-718-269-56X; 016-707-317-081-508; 019-920-853-002-203; 024-818-377-883-504; 026-395-112-558-483; 029-429-011-542-038; 030-289-314-381-511; 031-515-983-911-371; 032-361-291-518-488; 034-741-204-346-161; 035-707-297-119-538; 036-122-025-637-713; 037-459-005-272-729; 039-554-543-246-569; 041-415-390-245-259; 043-473-008-851-871; 051-631-697-690-639; 051-923-627-557-255; 061-449-512-549-535; 067-199-939-147-825; 068-923-152-897-05X; 076-071-135-709-750; 081-058-753-219-251; 081-280-377-250-948; 101-950-283-942-541; 105-351-670-532-738; 112-476-240-833-736; 122-960-424-023-292; 135-437-887-364-507; 137-120-972-247-556; 141-770-516-078-794; 144-711-515-519-673; 145-632-844-912-864; 180-817-757-067-615; 181-175-395-223-258,2,true,cc-by-nc-nd,hybrid -095-128-514-239-019,Untitled ItemResearch performance of a Peruvian medical students' scientific society in Scopus and Web of Science: a bibliometric analysis of Sociedad Científica de San Fernando,2023-01-01,2023,dataset,Figshare,,,,Alvaro Quincho-Lopez,"These datasets provide raw data for the analysis of the scientific production of medical students from a single university in Peru. The csv. format and text.txt can be analyzed with Bibliometrix R-tool and VOSviewer, and many other programs. The other tab delimited.txt can be analyzed with other online softwares.",,,,,Scopus; Web of science; Library science; Humanities; Political science; MEDLINE; Computer science; Art; Law,,,,,https://figshare.com/articles/dataset/Untitled_ItemResearch_performance_of_a_Peruvian_medical_students_scientific_society_in_Scopus_and_Web_of_Science_a_bibliometric_analysis_of_Sociedad_Cient_fica_de_San_Fernando/24036627/1,http://dx.doi.org/10.6084/m9.figshare.24036627.v1,,10.6084/m9.figshare.24036627.v1,,,0,,0,true,cc-by,gold -095-593-834-034-657,Identifying global trends and gaps in research on pesticide fipronil: a scientometric review.,2022-06-15,2022,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Sandrieli Gonçalves; Marina Wust Vasconcelos; Thaís Fernandes Mendonça Mota; Juliana Marceli Hofma Lopes; Larissa Juliane Guimaraes; Karina Silvia Beatriz Miglioranza; Nédia de Castilhos Ghisi,,29,52,79111,79125,Fipronil; Pesticide; Toxicology; Biology; Ecology,CiteSpace; Environment risk; Insecticide; Phenylpyrazoles; Toxicity. Bibliometrix,Animals; Bees; Insecticides/toxicity; Pesticides/toxicity; Chlorine; gamma-Aminobutyric Acid,fipronil; Insecticides; Pesticides; Chlorine; gamma-Aminobutyric Acid,,,http://dx.doi.org/10.1007/s11356-022-21135-8,35705759,10.1007/s11356-022-21135-8,,,0,000-777-488-771-709; 002-380-726-759-80X; 003-040-839-132-996; 004-691-794-039-565; 005-190-948-034-769; 009-238-189-315-097; 013-507-404-965-47X; 014-508-933-224-256; 015-761-552-076-697; 018-728-558-339-819; 019-076-140-824-310; 021-805-755-745-976; 021-838-863-249-532; 021-859-833-451-468; 023-620-543-445-199; 028-859-199-885-852; 030-589-491-168-10X; 032-029-493-004-181; 033-652-103-551-931; 036-656-168-693-890; 041-958-029-391-643; 049-210-823-603-376; 049-655-147-158-431; 050-145-997-389-055; 050-280-407-136-464; 054-022-732-362-848; 055-149-666-077-540; 059-844-654-753-708; 059-926-618-091-427; 063-058-499-693-907; 063-903-729-213-426; 071-686-534-153-496; 072-383-311-354-918; 074-130-510-995-336; 074-391-472-681-680; 075-213-726-178-626; 076-974-967-981-025; 078-389-791-018-731; 081-618-870-008-499; 085-723-376-364-594; 087-689-452-068-487; 087-894-137-613-812; 089-839-969-523-036; 095-801-180-663-967; 096-780-226-565-593; 097-308-381-238-282; 097-974-677-819-099; 100-039-045-364-558; 101-752-490-869-458; 103-938-548-219-561; 113-247-951-775-39X; 113-547-537-325-259; 116-317-511-537-785; 123-648-657-208-706; 128-980-820-958-694; 130-716-663-613-439; 138-093-245-599-710; 143-998-738-124-85X; 170-904-273-888-890; 185-547-470-325-415; 187-380-359-106-514,19,false,, -096-152-117-598-591,Is smart specialisation monopolising the research on the EU cohesion policy? Evidence from a bibliometric analysis,2022-12-23,2022,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Francesco Foglia,,128,2,1001,1021,Cohesion (chemistry); Regional science; Bibliometrics; Sustainability; Political science; Regional policy; Science policy; Research policy; Scientific literature; Computer science; Public administration; Sociology; Library science; Ecology; Paleontology; Chemistry; Organic chemistry; Law; Biology,,,,,,http://dx.doi.org/10.1007/s11192-022-04585-2,,10.1007/s11192-022-04585-2,,,0,001-829-625-498-656; 003-386-953-978-336; 003-607-076-269-728; 008-367-923-675-148; 010-049-777-354-247; 013-507-404-965-47X; 013-524-854-219-241; 016-291-227-858-575; 017-750-600-412-958; 024-617-819-502-14X; 028-224-270-975-975; 028-523-014-260-970; 031-589-226-167-84X; 037-091-873-048-986; 041-648-381-974-369; 046-189-637-704-648; 050-178-566-367-963; 051-647-739-244-271; 057-803-697-074-453; 057-869-078-852-449; 062-490-573-153-965; 065-220-549-811-55X; 065-685-431-494-085; 072-174-893-739-306; 074-689-637-760-304; 086-326-072-465-481; 093-218-840-885-661; 095-832-028-210-017; 098-335-082-916-135; 098-377-939-800-955; 102-307-163-561-465; 105-053-434-390-920; 107-276-900-991-821; 114-075-747-192-195; 120-974-286-046-262; 177-005-978-695-867; 184-577-133-030-318,2,false,, -096-217-818-540-477,Spatial exploration of plant functional types: insights from bibliometric meta-analysis,2025-04-23,2025,journal article,Discover Plants,30051207,Springer Science and Business Media LLC,,Garge Sandhya Kiran; Agradeep Mohanta; Ramandeep Kaur M. Malhi; Pankajkumar C. Prajapati; Kavi K. Oza; Shrishti Rajput,"The realm of ecology and environmental studies places immense significance on the concepts of plant functional traits (FTs) and plant functional types (PFTs), especially through spatial lens. The present study presents a bibliometric analysis of research on FTs and PFTs over the past decades (1993 to 2023). By analyzing 277 relevant publications, key trends, influential authors, and major contributors to this field, notable figures including Swenson NG, Reich PB, and Pottier J were identified. The analysis highlights the growing global interest in FTs and PFTs, particularly in the USA, Germany, and China, and the role of leading institutions such as the University of Oxford, Universidad Rey Juan Carlos, and the Chinese Academy of Sciences. A significant finding in this study is the increasing use of spatial technologies like Geographic Information Systems (GIS) and remote sensing, which have enhanced the understanding and categorization of PFTs. This work not only underscores the global scope and collaborative nature of this research but also identifies emerging areas for further exploration, particularly in the application of spatial techniques to ecological and environmental studies. In essence, this bibliometric analysis accentuates the synergy between spatial techniques and PFT research, emphasizing the potential of these innovations to drive future advancements in plant ecology.",2,1,,,Meta-analysis; Computer science; Geography; Medicine; Internal medicine,,,,,,http://dx.doi.org/10.1007/s44372-025-00203-6,,10.1007/s44372-025-00203-6,,,0,000-024-569-932-66X; 005-864-890-970-252; 005-940-671-873-366; 006-449-285-320-831; 007-663-998-736-398; 008-952-050-631-089; 009-919-783-110-223; 010-710-058-193-730; 011-662-696-248-380; 012-741-274-030-770; 015-212-100-406-26X; 016-180-225-826-471; 016-792-930-181-901; 019-380-066-066-932; 022-774-595-674-722; 023-081-675-698-93X; 023-323-473-351-363; 027-750-193-143-756; 029-038-786-997-179; 034-553-902-320-665; 034-761-399-705-766; 035-751-053-207-177; 036-056-658-591-986; 038-522-431-225-699; 040-288-337-875-731; 040-617-075-294-412; 044-113-431-410-00X; 044-808-566-509-681; 048-009-011-105-477; 050-623-270-109-204; 050-664-965-270-417; 057-967-329-552-491; 062-079-608-196-720; 065-471-302-587-302; 067-186-729-642-016; 069-441-261-156-765; 069-828-824-566-52X; 071-790-955-382-043; 073-391-707-871-213; 079-937-380-573-440; 080-472-607-269-258; 083-205-751-548-852; 084-739-836-972-794; 084-817-032-668-245; 088-144-493-220-461; 102-146-751-528-018; 106-614-866-017-621; 107-381-407-877-747; 107-452-141-732-721; 112-928-678-271-154; 114-234-293-524-954; 115-315-234-959-377; 121-481-540-525-244; 129-590-087-338-777; 130-522-141-085-856; 142-740-761-107-420; 150-486-890-689-729; 151-829-174-840-959; 158-297-450-015-032; 158-880-519-987-365; 161-471-287-994-021; 166-624-645-630-41X; 175-480-994-934-098; 178-914-600-158-204; 189-373-305-768-042,0,true,cc-by-nc-nd,hybrid -096-733-236-594-417,Bibliometric Analysis of Real Estate Investment Trusts Research,,2023,conference proceedings article,"Proceedings of the 3rd International Conference on Big Data Economy and Information Management, BDEIM 2022, December 2-3, 2022, Zhengzhou, China",,EAI,,Xiaoli Wang; Chuan Chen,"In order to understand the research trend and key fields of Real Estate Investment Trusts (REITs), a bibliometric analysis was conducted based on the Web of Science database and Bibliometrix. This study gives a comprehensive overview of the Real Estate Investment Trusts research according to annual",,,,,Real estate investment trust; Real estate; Investment (military); Business; Order (exchange); Estate; Finance; Computer science; Data science; Political science; Politics; Law,,,,,http://eudl.eu/pdf/10.4108/eai.2-12-2022.2332264 https://doi.org/10.4108/eai.2-12-2022.2332264,http://dx.doi.org/10.4108/eai.2-12-2022.2332264,,10.4108/eai.2-12-2022.2332264,,,0,,0,true,,bronze -096-887-073-024-939,Humanitarian supply chain: a bibliometric analysis and future research directions,2020-04-06,2020,journal article,Annals of Operations Research,02545330; 15729338,Springer Science and Business Media LLC,Netherlands,Samuel Fosso Wamba,,319,1,937,963,,,,,,,http://dx.doi.org/10.1007/s10479-020-03594-9,,10.1007/s10479-020-03594-9,,,0,001-158-030-451-387; 003-173-724-587-834; 004-357-427-046-217; 004-422-382-484-093; 010-612-118-670-49X; 010-678-247-632-774; 011-848-196-551-792; 013-507-404-965-47X; 013-636-396-823-084; 026-557-135-847-551; 033-072-313-748-096; 033-978-638-041-380; 035-443-977-306-787; 038-435-051-609-96X; 038-828-788-406-611; 039-180-555-316-153; 039-565-106-753-013; 039-766-777-162-370; 041-818-814-241-005; 043-164-786-791-108; 043-237-625-216-246; 045-993-333-977-461; 049-702-114-721-178; 051-638-982-159-179; 053-386-179-291-386; 055-666-469-824-784; 058-264-021-351-517; 058-575-445-685-033; 059-363-584-917-115; 059-502-333-665-846; 061-427-729-152-793; 061-678-439-796-853; 062-056-684-388-052; 062-522-687-734-50X; 063-923-482-584-492; 064-933-858-519-329; 065-241-933-308-636; 066-771-116-851-65X; 069-079-608-898-217; 069-758-661-058-369; 074-279-238-515-510; 076-986-699-509-469; 079-821-815-152-748; 088-384-837-898-640; 095-423-844-475-630; 097-322-543-563-717; 100-958-552-873-362; 104-495-326-573-684; 112-406-959-820-385; 112-679-068-880-337; 118-834-446-029-757; 124-301-674-681-486; 146-301-107-506-372; 147-400-828-228-309; 149-459-172-615-347; 149-879-244-312-11X; 152-641-033-222-382; 156-399-453-526-705; 175-543-825-459-682,56,false,, -097-190-698-749-282,Virtual Reality Based Training Simulator: A Bibliometric Analysis,2023-05-11,2023,conference proceedings article,2023 International Conference on Disruptive Technologies (ICDT),,IEEE,,Priyanka Datta; Amanpreet Kaur; Archana Mantri,"Innovation in immersive technologies is growing rapidly throughout the world with the development in industrial applications. In VR technology, a user is completely immersed in the virtual environment and totally detached from real world but feel the virtual world as real. This helps user to experience some scenario which is dangerous and costly in real time. Hence many VR Based Training Simulators (VRBTS) are developed. This paper presents Bibliometrix analysis on VRBTS domain, considering data from Scopus and Dimension databases. A scientific computer-assisted review approach called bibliometrix analysis can identify important researchers or authors as well as their connections across all the publications relevant to a specific field or subject.",,,666,671,Virtual reality; Computer science; Field (mathematics); Domain (mathematical analysis); Human–computer interaction; Virtual world; Dimension (graph theory); Scopus; Multimedia; Mathematical analysis; Mathematics; MEDLINE; Political science; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1109/icdt57929.2023.10150887,,10.1109/icdt57929.2023.10150887,,,0,001-975-832-201-443; 017-599-769-043-095; 030-070-985-228-781; 044-512-600-708-252; 049-673-234-918-16X; 050-462-635-420-464; 065-505-248-488-428; 084-308-624-928-471; 139-170-500-051-887; 161-058-916-768-547,1,false,, -097-275-110-511-613,Empowering music education with technology: a bibliometric perspective,2025-03-08,2025,journal article,Humanities and Social Sciences Communications,26629992,Springer Science and Business Media LLC,,Yidi Ma; Chengliang Wang,"As technology becomes an integral part of educational content and methodology, its research significance continues to grow, particularly in the relationship between music and technology. The primary aim of this study is to quantify and analyze academic research outcomes concerning the use of technology in music education. The selected sample is drawn from the WoS core database, encompassing academic achievements from 1991 to 2024. Various bibliometric software tools and three major laws were employed for the analysis, examining publication distribution, relevant journals and authors, research countries, keywords, and current and future research themes. Presently, research is mainly focused on four themes: technology integration and interaction, adaptive learning and creative teaching methods, educational frameworks and performance, and the diverse inclusion of children and adolescents. Looking ahead, the two frontier hot topics in this field are remote and online education, and innovation in higher education and educational models. This study aims to contribute to the comprehensive bibliometric analysis literature on the use of technology in music education.",12,1,,,Perspective (graphical); Sociology; Mathematics education; Computer science; Psychology; Artificial intelligence,,,,,,http://dx.doi.org/10.1057/s41599-025-04616-2,,10.1057/s41599-025-04616-2,,,0,001-428-280-180-732; 002-052-422-936-00X; 002-608-096-514-418; 004-115-092-307-54X; 005-032-393-247-600; 006-666-415-331-477; 007-454-056-008-791; 009-063-254-526-121; 012-488-538-496-341; 016-125-159-291-517; 018-017-080-759-249; 018-525-229-185-433; 021-098-483-449-355; 022-502-557-277-196; 023-695-280-483-21X; 027-073-295-470-138; 028-539-353-815-527; 030-014-805-549-013; 031-003-329-775-935; 032-073-939-842-680; 032-825-940-267-563; 033-780-474-281-172; 038-754-569-721-292; 039-049-544-383-138; 040-262-467-583-977; 042-890-431-384-378; 043-222-093-796-689; 044-849-862-159-955; 046-900-189-926-678; 046-992-864-415-70X; 055-862-162-745-799; 063-122-007-024-832; 066-757-022-108-741; 066-871-510-445-033; 066-987-985-547-45X; 067-608-071-914-19X; 069-151-793-570-603; 070-701-905-727-740; 072-534-571-050-094; 079-921-568-183-042; 082-196-551-869-688; 083-904-445-879-082; 084-033-907-429-170; 084-165-993-708-495; 085-479-188-014-27X; 089-305-898-082-950; 091-319-910-675-900; 091-950-652-780-269; 093-695-092-257-927; 095-759-728-823-078; 101-195-358-705-772; 110-879-065-569-176; 114-914-470-235-205; 118-177-080-170-424; 120-658-917-021-295; 123-126-227-533-260; 123-572-251-690-733; 125-019-795-530-235; 131-555-931-883-817; 131-753-890-446-115; 134-119-822-088-02X; 134-578-277-181-386; 140-284-329-785-24X; 143-769-460-965-89X; 145-521-393-589-567; 145-851-573-184-702; 148-449-111-516-956; 150-300-265-385-238; 150-355-037-280-635; 153-387-329-239-162; 162-647-519-534-191; 169-059-102-676-630; 174-811-374-953-690; 175-440-101-650-252; 175-630-620-777-762; 175-701-814-934-442; 188-070-622-990-419; 195-106-625-290-122; 197-047-444-027-777; 199-709-172-696-047,0,true,cc-by,gold -098-161-179-529-724,Barreras de la enseñanza y el entrenamiento en la manufactura. Una revisión bibliométrica.,2024-05-01,2024,journal article,"Dilemas contemporáneos: Educación, Política y Valores",20077890,Asesorias y tutorias para la Investigacion Cientifica en la Educacion Puig-Salabarria S.C.,,Fabiola Hermosillo Villalobos; Jorge Luis García Alcaraz; Omar Celis Gracia,"En este artículo se presenta una revisión bibliométrica sobre las barreras de la enseñanza y el entrenamiento en la industria de manufactura. Se realizó una búsqueda en la base de datos Scopus y se identificaron 915 documentos para su análisis que comprende del periodo de 1967 a 2023. Mediante el software Vosviewer y Bibliometrix se identifica una tendencia de investigación que va en aumento, las principales revistas que publican sobre el topico son la Sustainability (Switzerland), la Journal of Cleaner Production y la Lecture Notes in Mechanical Engineering y los autores más productivos son Misel Na, Wang Y y Williams Cb.",,,,,Political science; Humanities; Philosophy,,,,,,http://dx.doi.org/10.46377/dilemas.v11i3.4108,,10.46377/dilemas.v11i3.4108,,,0,,0,true,,gold -098-522-362-361-908,A Bibliometric Review of Brain-Computer Interfaces in Motor Imagery and Steady-State Visually Evoked Potentials for Applications in Rehabilitation and Robotics.,2024-12-30,2024,journal article,"Sensors (Basel, Switzerland)",14248220; 14243210,Multidisciplinary Digital Publishing Institute (MDPI),Switzerland,Nayibe Chio; Eduardo Quiles-Cucarella,"In this paper, a bibliometric review is conducted on brain-computer interfaces (BCI) in non-invasive paradigms like motor imagery (MI) and steady-state visually evoked potentials (SSVEP) for applications in rehabilitation and robotics. An exploratory and descriptive approach is used in the analysis. Computational tools such as the biblioshiny application for R-Bibliometrix and VOSViewer are employed to generate data on years, sources, authors, affiliation, country, documents, co-author, co-citation, and co-occurrence. This article allows for the identification of different bibliometric indicators such as the research process, evolution, visibility, volume, influence, impact, and production in the field of brain-computer interfaces for MI and SSVEP paradigms in rehabilitation and robotics applications from 2000 to August 2024.",25,1,154,154,Brain–computer interface; Motor imagery; Robotics; Computer science; Artificial intelligence; Human–computer interaction; Visibility; Field (mathematics); Rehabilitation; Visualization; Interface (matter); Neural engineering; Machine learning; Robot; Electroencephalography; Psychology; Neuroscience; Geography; Bubble; Maximum bubble pressure method; Parallel computing; Mathematics; Meteorology; Pure mathematics,brain–computer interface; motor imagery; rehabilitation; robot arm; robot hand; steady-state visually evoked potential,"Brain-Computer Interfaces; Humans; Robotics/methods; Evoked Potentials, Visual/physiology; Rehabilitation/methods; Bibliometrics; Imagination/physiology",,,,http://dx.doi.org/10.3390/s25010154,39796947,10.3390/s25010154,,PMC11722989,0,000-397-314-294-645; 000-579-987-982-474; 001-019-839-860-652; 002-052-422-936-00X; 006-090-756-599-616; 007-235-822-898-886; 007-891-591-949-070; 007-931-115-264-373; 012-252-640-811-044; 013-194-908-848-459; 013-944-885-371-714; 015-118-147-873-18X; 018-723-183-268-774; 019-512-653-144-618; 019-751-382-518-400; 024-890-317-279-23X; 026-316-070-793-478; 030-169-556-624-436; 030-184-283-941-721; 030-452-500-237-502; 034-587-384-400-790; 035-222-275-724-096; 035-222-693-362-382; 035-610-336-237-14X; 038-128-367-447-178; 038-261-340-325-886; 039-068-160-718-529; 039-482-834-931-953; 039-545-262-810-093; 040-429-115-162-177; 043-737-236-113-05X; 047-023-595-552-573; 047-346-362-380-033; 060-351-102-107-863; 060-907-254-768-792; 063-542-333-442-635; 065-010-405-236-060; 066-094-346-614-590; 071-581-285-318-85X; 072-733-407-709-178; 072-928-682-815-75X; 073-599-440-556-574; 077-324-572-749-039; 079-389-448-773-541; 080-044-448-019-313; 080-483-481-183-742; 081-965-987-917-262; 085-945-313-922-628; 091-653-954-448-316; 096-518-279-526-447; 098-695-730-372-893; 099-186-056-452-242; 101-887-147-381-285; 102-711-177-307-147; 115-639-707-998-052; 120-893-507-499-819; 124-325-328-334-621; 129-754-497-334-574; 134-090-510-494-591; 142-809-615-572-140; 152-219-247-626-178; 159-760-891-941-902; 162-435-487-238-296; 166-686-468-889-458; 181-945-552-389-875; 185-461-313-493-135,0,true,cc-by,gold -098-638-618-929-590,Reducing maritime accidents in ships by tackling human error: a bibliometric review and research agenda,2021-11-24,2021,journal article,Journal of Shipping and Trade,23644575,Springer Science and Business Media LLC,,Carine Dominguez-Péry; Lakshmi Narasimha Raju Vuddaraju; Isabelle Corbett-Etchevers; Rana Tassabehji,"Over the past decade the number of maritime transportation accidents has fallen. However, as shipping vessels continue to increase in size, one single incident, such as the oil spills from ‘super’ tankers, can have catastrophic and long-term consequences for marine ecosystems, the environment and local economies. Maritime transport accidents are complex and caused by a combination of events or processes that might ultimately result in the loss of human and marine life, and irreversible ecological, environmental and economic damage. Many studies point to direct or indirect human error as a major cause of maritime accidents, which raises many unanswered questions about the best way to prevent catastrophic human error in maritime contexts. This paper takes a first step towards addressing some of these questions by improving our understanding of upstream maritime accidents from an organisation science perspective—an area of research that is currently underdeveloped. This will provide new and relevant insights by both clarifying how ships can be described in terms of organisations and by considering them in a whole ecosystem and industry. A bibliometric review of extant literature of the causes of maritime accidents related to human error was conducted, and the findings revealed three main root causes of human and organisational error, namely, human resources and management, socio-technical Information Systems and Information Technologies, and individual/cognition-related errors. As a result of the bibliometric review, this paper identifies the gaps and limitations in the literature and proposes a research agenda to enhance our current understanding of the role of human error in maritime accidents. This research agenda proposes new organisational theory perspectives—including considering ships as organisations; types of organisations (highly reliable organisations or self-organised); complex systems and socio-technical systems theories for digitalised ships; the role of power; and developing dynamic safety capabilities for learning ships. By adopting different theoretical perspectives and adapting research methods from social and human sciences, scholars can advance human error in maritime transportation, which can ultimately contribute to addressing human errors and improving maritime transport safety for the wider benefit of the environment and societies ecologies and economies.",6,1,1,32,Human resources; Risk analysis (engineering); Information technology; Upstream (petroleum industry); Business; Human error; Information system; Human science; Marine life; Systems theory,,,,IDEX-IRS University of Grenoble Alpes,https://econpapers.repec.org/article/sprjosatr/v_3a6_3ay_3a2021_3ai_3a1_3ad_3a10.1186_5fs41072-021-00098-y.htm https://jshippingandtrade.springeropen.com/articles/10.1186/s41072-021-00098-y,http://dx.doi.org/10.1186/s41072-021-00098-y,,10.1186/s41072-021-00098-y,3216723884,,0,000-622-117-862-867; 001-415-306-433-222; 002-926-393-487-448; 002-950-541-158-719; 006-436-154-357-13X; 007-049-633-054-394; 007-819-624-453-64X; 009-421-480-805-484; 010-598-151-904-229; 011-628-157-715-825; 011-750-796-808-517; 011-763-088-393-376; 012-200-683-670-718; 012-634-873-592-579; 013-595-561-785-248; 013-629-731-782-027; 014-787-962-696-724; 015-931-813-026-081; 016-313-168-667-625; 017-037-246-019-788; 017-750-600-412-958; 018-247-008-796-970; 019-470-649-233-236; 020-163-511-558-80X; 020-386-693-026-254; 020-754-413-377-41X; 020-958-166-307-16X; 021-647-790-096-819; 022-512-643-506-628; 022-821-075-883-896; 023-084-510-323-308; 024-395-216-518-264; 024-789-607-081-823; 024-912-246-219-575; 025-787-345-065-168; 027-171-748-814-458; 027-351-255-329-049; 027-827-119-143-849; 028-953-765-789-461; 029-401-833-860-137; 030-387-712-986-179; 031-069-848-540-697; 031-187-339-565-260; 031-562-430-546-732; 032-876-097-410-273; 032-940-274-110-823; 033-127-677-566-360; 038-517-223-542-642; 038-679-719-592-688; 042-621-705-454-05X; 043-078-631-168-740; 043-955-709-390-192; 044-009-525-921-150; 046-248-832-472-499; 046-444-936-629-217; 047-134-478-431-993; 051-123-392-202-410; 051-309-910-781-543; 051-484-461-927-33X; 051-490-721-369-735; 053-044-454-752-918; 054-925-168-723-16X; 055-696-349-567-127; 056-361-307-491-55X; 058-861-773-627-892; 058-960-390-771-612; 059-136-069-465-310; 059-710-588-080-678; 060-997-411-325-55X; 063-148-648-960-431; 063-824-575-585-423; 064-457-591-739-247; 069-758-661-058-369; 070-560-489-015-261; 071-764-813-880-267; 071-794-642-679-469; 073-179-388-047-877; 073-701-383-473-163; 073-714-173-754-736; 077-376-196-674-348; 079-982-094-058-58X; 083-108-156-986-482; 083-750-682-490-91X; 085-982-760-315-603; 087-068-015-107-052; 088-026-048-953-600; 090-359-749-295-927; 091-694-909-427-402; 094-841-877-675-757; 095-722-075-874-484; 096-188-530-765-706; 098-172-529-280-126; 099-666-999-414-834; 099-927-171-123-589; 100-085-798-699-704; 102-003-864-227-846; 104-197-589-251-972; 106-458-055-177-080; 107-235-978-975-169; 107-298-851-348-123; 108-263-958-073-373; 108-631-307-545-978; 110-229-157-171-339; 111-672-884-534-290; 111-899-989-657-592; 112-051-062-119-295; 112-865-308-568-684; 115-482-499-323-938; 115-508-533-440-373; 115-913-817-588-619; 118-542-464-680-549; 123-640-563-191-855; 124-035-861-079-459; 126-766-525-351-515; 127-600-956-531-653; 133-808-895-312-958; 136-975-268-687-643; 137-951-063-271-652; 138-895-294-963-886; 139-832-126-629-801; 141-690-562-141-598; 143-431-047-977-901; 144-603-902-957-923; 145-831-492-921-733; 153-787-842-765-406; 166-492-338-087-160; 172-047-103-726-804; 173-129-132-510-936; 173-191-409-354-962; 175-884-562-914-246; 181-359-985-313-84X; 181-955-160-746-57X; 183-168-385-539-985; 183-352-042-704-117; 183-774-264-124-089; 184-424-940-113-112; 185-873-511-197-100; 189-962-892-212-553; 191-064-992-820-510; 192-214-151-913-867; 193-165-744-637-317; 193-614-309-115-769,31,true,cc-by,gold -098-648-038-105-666,A user-friendly method to merge Scopus and Web of Science data during bibliometric analysis,2021-10-22,2021,journal article,Journal of Marketing Analytics,20503318; 20503326,Springer Science and Business Media LLC,,Andrea Caputo; Mariya Kargina,,10,1,82,88,,,,,,,http://dx.doi.org/10.1057/s41270-021-00142-7,,10.1057/s41270-021-00142-7,,,0,001-153-564-508-98X; 002-052-422-936-00X; 002-889-632-858-980; 005-676-355-691-042; 008-146-495-921-306; 010-442-924-794-711; 013-507-404-965-47X; 017-300-737-144-757; 017-750-600-412-958; 020-769-541-764-758; 022-050-154-142-786; 026-125-810-364-184; 027-845-295-187-970; 041-910-360-555-238; 045-422-273-148-899; 045-797-416-772-535; 052-872-010-507-265; 067-461-470-339-184; 068-970-970-192-264; 069-764-890-140-842; 070-212-018-137-202; 070-665-150-453-490; 072-856-861-900-730; 080-688-314-803-632; 083-233-429-885-517; 085-300-287-100-525; 116-194-587-286-735; 123-202-581-406-928; 141-026-656-461-626; 151-066-640-236-837; 158-253-621-523-361; 195-638-802-395-994,139,false,, -098-839-831-378-733,Project-Based Learning in Science Education: A Bibliometric Network Analysis,2023-12-28,2023,journal article,International Journal on Studies in Education,26907909,ISTES Organization,,Meryem Konu Kadirhanogullari; Esra Ozay Kose,"The project-based learning model is the most common method used concerning transferring knowledge and skills gained from the courses of sciences to the daily lives of students. Through the relevant method, science courses are considered to be more efficient and understandable as well as to be more loved by the students. In this respect, it is of great importance to periodically examine the research on project-based learning in science education and to identify trends. In this study, it was aimed to determine the content analysis and trends of the studies on project-based learning in science education.  First, we registered 885 publications using “science education and project-based learning” in the “Social Sciences” category from Scopus, documents were then exported to CSV form and in turn, subjected to the bibliometric analysis using VOSviewer Software. In addition, the bibliometrix program was used for Lotka's law and author effect ratio. ",6,1,85,108,Scopus; Project-based learning; Social network analysis; Computer science; Mathematics education; Science education; Content analysis; Psychology; Sociology; Social science; World Wide Web; Political science; Social media; MEDLINE; Law,,,,,https://ijonse.net/index.php/ijonse/article/download/200/pdf https://doi.org/10.46328/ijonse.200,http://dx.doi.org/10.46328/ijonse.200,,10.46328/ijonse.200,,,0,,4,true,,gold -099-064-434-324-075,Qualitative analysis of information recorded in patents,2022-07-08,2022,book chapter,New Trends in Qualitative Research,21847770,Ludomedia,,Eduardo Amadeu Dutra Moresi; Isabel Pinho; Helga Cristina Hedler,"Patent is a valuable source of information to help evaluate trends in research, since it reveals the areas of innovation that inventors are focused on. Another relevant point is that it is public and reliable information. This paper aims to present an approach to generate subsidies for the qualitative interpretation of patents using the support of the conceptual structure of the R-Bibliometrix package. The methodology comprised data collection, detailing how the search was conducted in the Lens Database, and data analysis, which presents an overview of the R-Bibliometrix package and the conversion of the data to be imported and analyzed. This database allows preliminary analysis of technological outlooks using the resources available for visualization. The results show the 10 digrams extracted from the patent abstracts that have the highest frequencies; the dynamics of the technologies from the IPC codes, focusing on the evolution of the technology over time and the trend topics; the thematic map of the evolution of the concepts that were extracted from the abstracts of the granted patents and patent applications; and the microstructure of the technological routes of the researched topic. It is concluded that patents offer opportunities for information analysis with a focus on technology and innovation. Despite not meeting all the requirements of a qualitative analysis, the R-Bibliometrix package offers several resources that support the analysis of the conceptual structure with the visualization of conceptual and technological routes, as well as allowing other possibilities for analysis of the intellectual and social structure.",,,,,Patent visualisation; Visualization; Patent analysis; Data science; Thematic analysis; Conceptual framework; Computer science; Knowledge management; Qualitative research; Data mining; Sociology; Social science,,,,,https://publi.ludomedia.org/index.php/ntqr/article/download/616/599 https://doi.org/10.36367/ntqr.12.2022.e616 https://publi.ludomedia.org/index.php/ntqr/article/download/616/599/1298 https://publi.ludomedia.org/index.php/ntqr/article/view/616/599,http://dx.doi.org/10.36367/ntqr.12.2022.e616,,10.36367/ntqr.12.2022.e616,,,0,,0,true,cc-by-nc-nd,gold -099-210-949-194-575,RESEARCH MAPPING ON CORPORATE TAX AVOIDANCE: STUDI BIBLIOMETRIX VOSVIEWERS DAN LITERATURE REVIEW,2024-12-10,2024,journal article,"Jurnal Akuntansi, Keuangan, Perpajakan dan Tata Kelola Perusahaan",30259223,Yayasan Nuraini Ibrahim Mandiri,,Noerma Widyaswara Utami; Sri Andriani,"Studi ini memiliki tujuan untuk melakukan pemetaan penelitian tentang penghindaran pajak perusahaan dengan menggunakan pendekatan mixmethod, yaitu studi bibliometrik VOSviewer dan literatur review. Penelitian dilakukan selama jangka waktu 7 tahun dari tahun 2017 hingga tahun 2024 dengan menggunakan aplikasi Publish or Perish dengan kata kunci Tax Avoidance. Penelitian ini memperoleh 199 artikel penelitian.. Hasil penelitian menunjukkan bahwa berdasarkan hasil analisis visualisasi VOSviewer, yang membagi penelitian tentang Corporate Tax Avoidance menjadi 5 kluster yang berbeda.",2,2,549,555,Tax avoidance; Corporate tax; Business; Political science; Economics; Accounting; Double taxation; Public economics,,,,,,http://dx.doi.org/10.70248/jakpt.v2i2.916,,10.70248/jakpt.v2i2.916,,,0,,0,false,, -100-048-540-453-835,The use of artificial intelligence to advance sustainable supply chain: retrospective and future avenues explored through bibliometric analysis,2024-07-31,2024,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Ibtissam Zejjari; Issam Benhayoun,"AbstractKeeping up with the hastily growing economy implies undergoing unremitting transformation permanently. In the field of supply chain, such progress can only be guaranteed via the exploration of new horizons and innovative solutions in response to the constraints of the global market. Emerging technologies, particularly artificial intelligence, offer promising avenues for enhancing supply chain processes, with sustainability ascending as a critical consideration. Despite the recent surfacing of AI-driven applications, scant attention has been devoted to exploring their full potential within supply chain operations, particularly in conjunction with SDGs. Recognizing the untapped opportunities presented by the implementation of AI for a sustainable supply chain this study undertakes a bibliometric analysis of 236 research papers sourced from the Web of science database. The analysis utilizes R language BiblioShiny to examine the extracted papers, and dissect patterns, trends, and relationships among key concepts and themes as well as prominent topics, impactful authors, and leading journals and countries in this domain. The findings reveal substantial growth in research related to SCM, AI, and sustainability as the UK leads this field of study with 132 articles followed by India, China and the USA. Eventually, the National University of Singapore came first in terms of paper affiliations, followed by De La Salle University, and London Metropolitan University. These results only prove that sustainability is becoming more critical in the equation of AI-driven supply chains especially with the current socio-political and economic circumstances, constituting a solid base for further academic research and more innovations in the managerial and business-related policies in this field.",5,1,,,Sustainability; Supply chain; Field (mathematics); Politics; Metropolitan area; Supply chain management; Regional science; Emerging markets; China; Political science; Business; Management science; Marketing; Economics; Sociology; Geography; Ecology; Mathematics; Archaeology; Finance; Pure mathematics; Law; Biology,,,,,https://link.springer.com/content/pdf/10.1007/s43621-024-00364-6.pdf https://doi.org/10.1007/s43621-024-00364-6 https://hal.science/hal-04671595/document https://hal.science/hal-04671595,http://dx.doi.org/10.1007/s43621-024-00364-6,,10.1007/s43621-024-00364-6,,,0,003-764-149-714-845; 007-070-712-080-175; 007-707-632-551-788; 007-735-388-398-109; 008-221-285-105-615; 008-417-185-917-514; 009-012-095-853-212; 013-507-404-965-47X; 014-165-976-054-910; 017-750-600-412-958; 018-993-818-429-712; 020-581-472-422-02X; 033-928-141-564-105; 041-518-834-335-477; 044-136-656-054-319; 049-391-379-302-694; 053-402-417-293-502; 054-762-124-818-059; 061-577-280-509-652; 062-570-755-047-573; 077-571-063-166-597; 082-412-978-142-019; 088-123-859-925-106; 093-066-752-514-350; 104-064-749-633-621; 107-777-651-434-586; 111-275-064-580-057; 119-779-720-173-303; 131-285-602-533-181; 134-985-477-712-653; 158-871-595-477-223; 189-466-455-736-057; 189-993-270-444-626; 196-852-472-136-773; 196-973-525-727-78X,9,true,cc-by,gold -100-262-505-407-187,Trends and gaps in hydroxychloroquine and COVID-19 research (2020-2023): Performance and conceptual mapping.,2024-12-18,2024,journal article,Journal of infection and public health,1876035x; 18760341,Elsevier BV,Netherlands,Abdullah Algaissi; Manal Mohamed Elhassan Taha; Edrous Alamer; Nader Kameli; Abdulaziz Alhazmi; Nizar Khamjan; Siddig Ibrahim Abdelwahab,"Hydroxychloroquine and Chloroquine (CQ) and Hydroxychloroquine (HCQ) are antimalarial drugs with well-known anti-inflammatory and antiviral effects used to treat various diseases, with few side effects. After COVID-19 emergence, numerous researches from around the world have examined the potential of using CQ or HCQ as potential treatment of COVID-19. However, conflicting outcomes have been found in COVID-19 clinical trials after treatment with CQ or HCQ. This study aims to evaluate research on CQ and HCQ for COVID-19 treatment and prophylaxis control using bibliometric methods.; We analyzed bibliometric data on HCQ and COVID-19 (HCQ-C19) quantitatively and semantically (2020-2023) using the Scopus database VOSviewer, Bibliometrix, and MS Excel.; Analyses of 7471 original and conference articles revealed that the total number of publications has continually increased. The country producing the most articles in this field was the United States, followed by Italy, India, and Spain. The top-productive authors on HCQ-C19 are Mussini, C., and Raoult, D. (Italy) with 23 and 21 articles, respectively. The top-impactful organization is IHU Méditerranée Infection, France. A Bibliometrix's network analysis based on the co-occurrence of keywords revealed the following themes HCQ-C19, including ""clinical research/practice,"" ""COVID-19,"" ""thrombosis,"" ""HCQ,"" ""epidemiology,"" and ""infectious disease.""; In conclusion, the analysis reveals a growing interest in HCQ-C19 research. Prominent contributions come from the United States, Italy, India, and Spain. Key themes include clinical research/practice, COVID-19, thrombosis, HCQ, epidemiology, and infectious disease. Future recommendations include conducting well-designed clinical trials and fostering collaborative interdisciplinary efforts.; Copyright © 2024. Published by Elsevier Ltd.",18,3,102623,102623,Hydroxychloroquine; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Pandemic; Medicine; Virology; Internal medicine; Disease; Outbreak; Infectious disease (medical specialty),Bibliometric analysis; Bibliometrix; COVID-19; Hydroxychloroquine; VOSviewer,Hydroxychloroquine/therapeutic use; Humans; COVID-19 Drug Treatment; Bibliometrics; COVID-19; Antiviral Agents/therapeutic use; SARS-CoV-2; Chloroquine/therapeutic use; Biomedical Research/trends; Antimalarials/therapeutic use; India,Hydroxychloroquine; Antiviral Agents; Chloroquine; Antimalarials,"Deanship of Scientific Research, King Saud University; Jazan University",,http://dx.doi.org/10.1016/j.jiph.2024.102623,39813964,10.1016/j.jiph.2024.102623,,,0,001-058-833-110-799; 002-052-422-936-00X; 002-674-616-978-378; 002-889-632-858-980; 003-423-666-888-215; 003-991-400-847-315; 004-346-778-977-490; 005-041-008-472-401; 005-352-288-137-090; 006-136-698-460-480; 006-814-288-920-288; 007-826-092-983-775; 008-070-071-182-847; 008-600-147-589-121; 008-975-160-578-532; 010-194-028-604-828; 013-366-969-883-504; 013-507-404-965-47X; 016-653-244-253-995; 017-059-478-767-328; 017-970-687-617-669; 018-893-593-725-44X; 019-198-640-323-614; 021-053-357-181-053; 023-182-754-295-998; 023-840-762-570-779; 025-738-368-428-303; 029-410-830-878-395; 034-732-911-805-318; 034-850-794-993-344; 036-278-922-594-558; 036-871-634-296-06X; 037-754-240-052-090; 044-003-286-726-19X; 044-299-622-492-472; 046-552-048-341-694; 046-845-534-522-799; 047-403-884-794-696; 049-520-016-298-786; 049-767-075-163-157; 050-789-751-041-132; 052-676-304-577-930; 053-009-557-549-599; 054-195-197-145-870; 056-652-243-242-588; 063-385-103-553-915; 063-956-838-180-837; 069-197-730-831-558; 070-139-050-488-784; 075-414-801-688-177; 075-462-933-951-228; 078-094-105-637-842; 080-488-009-860-511; 081-582-027-340-71X; 094-548-831-852-903; 097-897-347-831-304; 102-673-498-815-199; 113-465-278-974-131; 115-514-698-029-639; 117-774-541-620-15X; 119-235-273-513-023; 120-975-417-040-341; 121-834-838-906-956; 126-443-888-519-114; 126-613-352-250-056; 139-611-798-849-007; 177-295-851-140-408; 177-751-527-046-985; 183-881-629-124-318,0,true,"CC BY, CC BY-NC-ND",gold -100-282-184-092-812,Bibliometric Analysis of Household Physics in Scopus Database: Approaches with Bibliometrix R-package and VOSviewer (Review of Literature on Home Physics Education),2024-06-26,2024,journal article,Jurnal Ilmiah Pendidikan Fisika,25499963; 25499955,"Center for Journal Management and Publication, Lambung Mangkurat University",,Fatra Faiza Majid; Buyamin Buyamin,"This study conducts bibliometric research using the Bibliometrix R-package analysis and VOSviewer to analyse Scopus databases from 1921 to 2024, specifically focusing on physics and households. It aims to determine the number of writings on home physics education in scientific publications, analyse publication trends, identify prolific authors, identify frequently used keywords and subject areas, and identify the countries that make the most contributions to publication. The research study found one article and was the only one published in 1921, entitled ""The Evolution of Nerve Muscle Mechanisms"" written by Russell S.B. Davies M and Kutner R were the two most productive authors, ""radon"" became the most widely used author keyword in publications. Physics and astronomy became the topics of the most frequently appearing publications. The U.S. emerged as the largest publisher and the most collaborative among the countries involved in the publication. Moreover, Indonesia has become the fifth-largest publisher in the world. Out of all the study papers, only five addressed home physics education. To encourage researchers, lecturers, and students to publish findings and research results linked to household physics in international scientific journals, it is believed that the findings of this study will be useful to higher education and research institutes.",8,2,194,194,Scopus; Physics; Library science; Data science; Computer science; MEDLINE; Political science; Law,,,,,,http://dx.doi.org/10.20527/jipf.v8i2.12106,,10.20527/jipf.v8i2.12106,,,0,,0,false,, -100-434-759-415-302,Automatic Merging of Scopus and Web of Science Data for Simplified and Effective Bibliometric Analysis,2022-08-07,2022,journal article,Annals of Data Science,21985804; 21985812,Springer Science and Business Media LLC,,HimaJyothi Kasaraneni; Salini Rosaline,,11,3,785,802,Scopus; Computer science; Process (computing); Web of science; Data mining; Information retrieval; Data science; Database; Bibliometrics; MEDLINE; Political science; Law; Operating system,,,,,,http://dx.doi.org/10.1007/s40745-022-00438-0,,10.1007/s40745-022-00438-0,,,0,002-596-427-175-559; 008-146-495-921-306; 010-442-924-794-711; 010-691-074-303-118; 013-507-404-965-47X; 017-300-737-144-757; 022-050-154-142-786; 033-774-000-117-345; 034-395-341-868-864; 034-768-039-318-254; 037-129-629-804-47X; 045-422-273-148-899; 045-797-416-772-535; 046-992-864-415-70X; 049-303-089-841-806; 051-862-424-436-262; 068-970-970-192-264; 070-212-018-137-202; 079-388-097-137-118; 085-300-287-100-525; 088-862-853-155-242; 098-648-038-105-666; 106-496-500-313-325; 109-512-644-843-372; 116-711-604-423-897; 140-653-371-364-191,19,false,, -100-825-069-591-42X,Bibliometric Analysis of Publications on Decentralization and Social Policy,2024-11-28,2024,journal article,Journal of Ecohumanism,27526801; 27526798,Creative Publishing House,,Fabian Cobos-Alvarado; Mónica Peñaherrera-León; Juan Carlos Merchán Alvarado; Benjamín Wilson León Valle; Jorge Enrique Saavedra-Palma,"This article presents a bibliometric analysis of articles in Scopus on “decentralization” and “social policy”, using the tools Vosviewer and Bibliometrix. The introduction highlights the growing importance of these areas in academic research and the need for rigorous methods to assess their evolution. The aim of the study is to quantify and validate categories related to these topics in order to obtain an objective and detailed perspective of current trends in the literature. The methodology employed includes the collection and analysis of bibliographic data from Scopus using specialized tools to map collaboration networks and emerging areas of research. The results indicate that bibliometric methods are effective in measuring and validating research categories that could be subjective in traditional reviews. In addition, they facilitate the exploration of new areas and allow the identification of emerging categories in the study of decentralization and social policy.",3,8,,,Decentralization; Political science; Regional science; Social science; Sociology; Law,,,,,https://ecohumanism.co.uk/joe/ecohumanism/article/download/4947/4557 https://doi.org/10.62754/joe.v3i8.4947,http://dx.doi.org/10.62754/joe.v3i8.4947,,10.62754/joe.v3i8.4947,,,0,,0,true,cc-by-nc-nd,hybrid -101-020-253-089-606,Tren Riset Pendekatan STEAM (2018-2022): Analisis Bibliometrik,2024-01-25,2024,journal article,Scholaria: Jurnal Pendidikan dan Kebudayaan,25499653; 20883439,Universitas Kristen Satya Wacana,,null Wulan Aulia Azizah; null Nur Indah Wahyuni,"Studi ini mengkaji tren penelitian STEAM Education selama lima tahun terakhir. Penelitian ini bertujuan untuk mengetahui: (1) Siapa penulis paling produktif; (2) Afiliasi paling produktif; (3) Negara paling produktif; (4) Visualisasi tren penelitian STEAM; dan (5) Topik penelitian masa depan. Penelitian ini menggunakan metode penelitian Bibliometrik. Basis data Scopus digunakan untuk mengumpulkan data, yang kemudian diubah menjadi RIS. Peneliti melakukan analisis data dengan perangkat lunak Rstudio, bibliometrix, dan VosViewer. Berdasarkan analisis, jumlah penelitian tentang STEAM mengalami peningkatan yang signifikan dari tahun 2018 hingga tahun 2022. Hal ini menunjukkan bahwa STEAM Education berdampak besar pada bidang pendidikan, khususnya pembelajaran. Selain itu, diketahui bahwa penelitian STEAM telah banyak dipelajari di Asia, khususnya di China. Namun, berdasarkan analisis bibliometrix menunjukkan bahwa Korea Selatan menjadi negara yang paling banyak disitasi internasional terkait penelitian pendekatan STEAM. Berdasarkan temuan juga menunjukkan bahwa menghubungkan Pendidikan STEAM dengan budaya lokal memiliki peluang penelitian di masa depan dalam pendidikan STEAM. Oleh karena itu, implikasi pada penelitian ini menharapkan adanya penelitian lebih lanjut terkait implementasi pendekatan STEAM terintegrasi budaya untuk meningkatkan keterampilan siswa.",14,1,68,78,Economics,,,,,https://ejournal.uksw.edu/scholaria/article/download/10346/2658 https://doi.org/10.24246/j.js.2024.v14.i01.p68-78,http://dx.doi.org/10.24246/j.js.2024.v14.i01.p68-78,,10.24246/j.js.2024.v14.i01.p68-78,,,0,,0,true,cc-by,gold -101-080-805-481-636,Mapping the Scholarly Landscape of Entrepreneurship Education Research in Higher Education Institutions: A Comprehensive Bibliometric Overview,2024-05-07,2024,journal article,Journal of Higher Education Theory and Practice,21583595,North American Business Press,,Asit K. Mantry; Biswabhusan Pradhan; Tarandeep Kour; Surbhi Tak; Surjit Kumar Lalotra,"This study aims to assess the trends of entrepreneurship education research in higher education between 1993 and 2022 using bibliometric analysis. A total of 1309 seminal articles were identified from the Scopus database and used advanced bibliometrix tools for analysis. The research findings revealed that the United States and the United Kingdom had taken the lead in entrepreneurship education research. Notably, author Bell R emerged as a prominent figure in this field. By scrutinizing the articles, it was also evident that keywords such as entrepreneurship education, business education, entrepreneurship, entrepreneurial intention, and entrepreneurial education hold significance within the domain. The insights gleaned from this analysis suggest valuable strategic information to researchers and aid them in formulating and mapping out future studies in entrepreneurship education.",24,4,,,Scopus; Entrepreneurship; Entrepreneurship education; Higher education; Bibliometrics; Field (mathematics); Political science; Business education; Sociology; Social science; Public relations; Library science; Computer science; Law; Mathematics; MEDLINE; Pure mathematics,,,,,https://articlegateway.com/index.php/JHETP/article/download/6951/6557 https://doi.org/10.33423/jhetp.v24i4.6951,http://dx.doi.org/10.33423/jhetp.v24i4.6951,,10.33423/jhetp.v24i4.6951,,,0,,0,true,,bronze -101-351-418-951-468,Knowledge map of programmed cell death in esophageal cancer: a bibliometric analysis.,2025-04-24,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Rulin Li; Yanchun Yang; Yang Gao; Jing Lv; Chuanqiang Dai; Yuanwei Zhai; Chirong Mao; Jiudong Jiang; Jiangang Fan; Yang Yu; Liang Wu; Zhiwu Lin,"This study aimed to delineate the evolving knowledge structure of programmed cell death in esophageal cancer and identify key thematic trends, influential collaborations, and emerging areas for future research.; A bibliometric approach was applied to 2677 publications retrieved from the Web of Science Core Collection (2000-2024). Three complementary tools-CiteSpace, VOSviewer, and bibliometrix-were employed to visualize co-citation networks, detect citation bursts, and map collaborative patterns among authors, institutions, and countries. Inclusion criteria focused on articles and reviews that addressed esophageal cancer in conjunction with apoptosis, necroptosis, pyroptosis, ferroptosis, autophagy, or related pathways.; Publication outputs grew markedly, reflecting a shift from early investigations of basic apoptotic mechanisms to broader explorations of necroptosis, pyroptosis, and ferroptosis. China led in publication volume and citations, driven by substantial governmental funding and large clinical cohorts. The United States and Japan also contributed significantly, forming international research networks that spanned Asia and Europe. Leading institutions, particularly Zhengzhou University, demonstrated extensive collaborations. Journals such as Oncology Letters and Oncology Reports were prominent outlets for new findings, while highly cited references highlighted hypoxia, immune checkpoint blockade, and emerging gene-editing strategies. Keyword analyses revealed the ascendance of immuno-oncology, network pharmacology, and translational applications targeting multiple regulated cell death pathways.; Bibliometric evidence underscores a rapid expansion of multidisciplinary research that integrates diverse cell death pathways in esophageal cancer. Continued international collaborations, leveraging advanced genomics and immunologic strategies, are poised to accelerate translational breakthroughs and enable more personalized, effective therapies.; © 2025. The Author(s).",16,1,609,,Esophageal cancer; Programmed cell death; Cancer; Computer science; Medicine; Apoptosis; Biology; Internal medicine; Genetics,Apoptosis; Autophagy; Esophageal cancer; Necroptosis; Programmed cell death,,,,,http://dx.doi.org/10.1007/s12672-025-02376-8,40274628,10.1007/s12672-025-02376-8,,PMC12022209,0,001-149-534-839-145; 003-952-896-426-300; 007-256-000-364-415; 008-528-664-982-673; 011-233-877-278-284; 011-935-974-084-584; 013-205-990-029-25X; 013-745-328-117-842; 013-783-644-216-137; 017-229-654-939-379; 028-735-912-646-626; 033-048-298-662-998; 033-688-534-443-849; 034-498-044-037-88X; 034-868-874-865-209; 035-477-745-232-69X; 036-081-033-013-814; 037-202-945-972-115; 043-661-850-125-757; 044-552-034-970-665; 046-556-592-801-955; 054-524-281-919-781; 057-245-654-364-027; 064-431-426-654-287; 066-734-273-471-332; 067-619-341-576-949; 070-721-999-751-087; 071-018-212-906-586; 074-702-026-939-042; 075-666-155-937-570; 078-023-058-890-141; 082-564-492-629-321; 085-476-694-328-251; 094-108-328-908-86X; 098-143-930-451-865; 100-996-996-552-073; 102-511-811-618-182; 102-979-405-667-820; 104-933-762-928-75X; 105-540-443-374-787; 107-483-302-885-238; 109-999-723-224-825; 110-127-033-583-14X; 114-772-278-258-422; 123-481-716-477-550; 123-930-924-817-75X; 125-698-131-443-902; 126-658-715-031-864; 138-164-639-367-045; 146-201-514-520-405; 151-793-220-553-933; 151-965-162-642-37X; 156-553-728-083-951; 158-140-005-149-037; 158-491-690-230-62X; 163-129-495-721-780; 168-777-642-934-004; 175-438-611-523-023; 188-553-283-794-726,0,true,cc-by,gold -101-463-334-620-369,"Citation Classics in Consumer Neuroscience, Neuromarketing and Neuroaesthetics: Identification and Conceptual Analysis.",2021-04-27,2021,journal article,Brain sciences,20763425,MDPI AG,Switzerland,Pablo Sánchez-Núñez; Manuel Cobo; Gustavo Vaccaro; José Ignacio Peláez; Enrique Herrera-Viedma,"Neuromarketing, consumer neuroscience and neuroaesthetics are a broad research area of neuroscience with an extensive background in scientific publications. Thus, the present study aims to identify the highly cited papers (HCPs) in this research field, to deliver a summary of the academic work produced during the last decade in this area, and to show patterns, features, and trends that define the past, present, and future of this specific area of knowledge. The HCPs show a perspective of those documents that, historically, have attracted great interest from a research community and that could be considered as the basis of the research field. In this study, we retrieved 907 documents and analyzed, through H-Classics methodology, 50 HCPs identified in the Web of Science (WoS) during the period 2010-2019. The H-Classic approach offers an objective method to identify core knowledge in neuroscience disciplines such as neuromarketing, consumer neuroscience, and neuroaesthetics. To accomplish this study, we used Bibliometrix R Package and SciMAT software. This analysis provides results that give us a useful insight into the development of this field of research, revealing those scientific actors who have made the greatest contribution to its development: authors, institutions, sources, countries as well as documents and references.",11,5,548,,Sociology; Perspective (graphical); Consumer behaviour; Data science; Consumer neuroscience; Core Knowledge; Neuromarketing; Field (computer science); Scientometrics; Identification (information),Bibliometrix; H-index; SciMAT; consumer behaviour; consumer neuroscience; consumer psychology; highly cited papers (HCPs); science mapping analysis; scientometrics,,,,https://rodin.uca.es/xmlui/handle/10498/25202 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146570 https://europepmc.org/article/MED/33925436 https://www.mdpi.com/2076-3425/11/5/548/pdf https://www.mdpi.com/2076-3425/11/5/548 https://pubmed.ncbi.nlm.nih.gov/33925436/,http://dx.doi.org/10.3390/brainsci11050548,33925436,10.3390/brainsci11050548,3159403669,PMC8146570,0,001-258-703-170-685; 002-339-774-733-546; 002-995-319-690-05X; 007-016-826-558-870; 007-137-317-965-364; 007-425-181-545-85X; 007-677-217-960-678; 007-773-466-302-609; 007-978-765-780-538; 009-005-488-459-35X; 010-336-397-325-374; 010-931-702-311-654; 011-245-815-311-286; 012-798-847-575-581; 013-507-404-965-47X; 013-524-854-219-241; 020-617-663-796-632; 022-088-332-100-559; 023-211-156-419-268; 023-328-938-154-056; 023-929-256-265-06X; 029-420-167-353-195; 030-653-365-110-752; 030-715-055-171-243; 031-632-135-351-626; 032-690-009-061-654; 034-154-058-064-652; 034-687-081-122-322; 034-991-008-221-021; 036-668-487-151-384; 037-091-873-048-986; 037-156-063-028-582; 039-204-483-882-546; 042-790-238-908-258; 043-941-758-583-890; 044-473-745-455-162; 046-819-537-627-036; 049-971-591-665-24X; 051-647-739-244-271; 052-564-531-798-147; 055-273-552-334-543; 055-956-013-020-927; 057-027-778-315-651; 058-325-232-213-663; 060-110-039-971-60X; 063-821-323-132-627; 065-678-790-623-357; 065-746-695-000-161; 067-408-526-114-345; 074-543-813-019-856; 075-382-587-426-470; 075-534-568-367-380; 078-470-166-296-718; 079-356-361-219-897; 082-846-871-027-73X; 086-715-810-300-881; 087-290-900-730-864; 092-913-048-542-073; 101-463-334-620-369; 101-639-724-415-543; 101-752-490-869-458; 110-172-537-905-096; 110-716-023-575-256; 115-993-512-481-493; 119-557-426-467-219; 133-564-791-478-082; 135-695-423-063-257; 143-887-110-842-192; 151-422-424-718-338; 151-499-281-383-686,11,true,cc-by,gold -101-553-093-664-502,Two decades of rice research in Indonesia and the Philippines: A systematic review and research agenda for the social sciences.,2022-10-14,2022,journal article,Humanities & social sciences communications,26629992,Springer Science and Business Media LLC,England,Ginbert P Cuaton; Laurence L Delina,"While rice studies are abundant, they usually focus on macro-level rice production and yield data, genetic diversity, cultivar varieties, and agrotechnological innovations. Moreover, many of these studies are either region-wide or concentrated on countries in the Global North. Collecting, synthesizing, and analyzing the different themes and topic areas in rice research since the beginning of the 21st century, especially in the Global South, remain unaddressed areas. This study contributes to filling these research lacunae by systematically reviewing 2243 rice-related articles cumulatively written by more than 6000 authors and published in over 900 scientific journals. Using the PRISMA 2020 guidelines, this study screened and retrieved articles published from 2001 to 2021 on the various topics and questions surrounding rice research in Indonesia and the Philippines-two rice-producing and -consuming, as well as emerging economies in Southeast Asia. Using a combination of bibliometrics and quantitative content analysis, this paper discusses the productive, relevant, and influential rice scholars; key institutions, including affiliations, countries, and funders; important articles and journals; and knowledge hotspots in these two countries. It also discusses the contributions of the social sciences, highlights key gaps, and provides a research agenda across six interdisciplinary areas for future studies. This paper mainly argues that an interdisciplinary and comparative inquiry of potentially novel topic areas and research questions could deepen and widen scholarly interests beyond conventional natural science-informed rice research in Indonesia and the Philippines. Finally, this paper serves other researchers in their review of other crops in broader global agriculture.",9,1,372,,Bibliometrics; Diversity (politics); Agriculture; Social science; Political science; Regional science; Geography; Sociology; Library science; Archaeology; Computer science; Law,Development studies; Environmental studies,,,,https://www.nature.com/articles/s41599-022-01394-z.pdf https://doi.org/10.1057/s41599-022-01394-z,http://dx.doi.org/10.1057/s41599-022-01394-z,36258775,10.1057/s41599-022-01394-z,,PMC9562066,0,000-633-763-229-314; 001-462-499-058-386; 002-913-748-716-869; 003-263-379-630-174; 003-683-279-418-580; 004-294-840-773-383; 005-687-526-082-270; 005-850-518-219-465; 006-534-111-396-613; 006-831-052-001-394; 007-317-520-742-893; 008-156-593-340-838; 008-842-266-976-644; 010-234-877-388-879; 010-308-193-526-694; 010-640-378-296-666; 011-253-907-434-507; 012-075-248-574-529; 012-096-452-730-026; 012-303-948-208-951; 013-176-210-892-272; 013-507-404-965-47X; 015-150-842-218-662; 015-442-351-311-357; 016-625-574-497-409; 017-255-380-014-633; 017-353-757-710-292; 017-714-391-133-304; 017-750-600-412-958; 017-889-580-233-296; 019-271-878-580-432; 019-528-036-421-794; 020-103-431-847-148; 020-264-043-174-292; 022-211-289-590-863; 023-409-544-576-648; 023-575-972-753-341; 023-624-086-580-296; 024-346-907-310-541; 025-455-547-885-50X; 025-567-454-408-815; 025-893-392-067-325; 025-930-864-838-600; 026-801-803-460-937; 027-434-527-905-948; 027-530-953-681-756; 027-961-123-744-513; 028-203-192-341-80X; 029-641-419-349-037; 030-299-380-475-961; 030-501-621-717-471; 030-514-895-386-596; 030-917-266-402-369; 031-051-163-356-429; 031-370-121-025-136; 031-411-792-086-78X; 032-241-382-286-209; 033-023-732-334-620; 033-738-955-072-372; 034-465-521-895-203; 034-549-911-398-534; 034-644-552-336-707; 035-822-129-159-593; 036-878-376-449-626; 037-300-222-685-680; 037-358-052-539-219; 038-358-324-982-537; 038-798-859-948-131; 040-310-990-635-616; 041-137-499-339-892; 041-261-047-159-426; 041-318-093-332-116; 041-922-220-350-28X; 041-947-439-358-105; 042-066-701-758-89X; 042-610-425-179-045; 042-706-678-585-160; 043-198-935-135-40X; 043-276-820-883-388; 043-648-125-707-459; 044-210-586-704-496; 044-835-443-009-066; 045-182-304-901-389; 045-368-114-501-494; 046-023-872-046-681; 046-992-864-415-70X; 047-358-360-469-585; 047-497-615-178-035; 047-533-275-780-315; 047-567-407-547-511; 047-610-623-303-31X; 048-798-075-184-930; 049-072-851-136-020; 049-378-326-074-724; 049-549-579-937-472; 049-828-108-263-995; 050-427-506-091-453; 050-664-965-270-417; 051-221-852-883-245; 051-974-583-724-823; 052-364-607-477-221; 053-151-679-477-711; 056-220-374-659-077; 058-092-492-914-541; 058-321-393-020-485; 058-345-750-783-939; 058-594-422-356-601; 059-371-505-801-22X; 059-709-701-962-667; 061-032-686-164-99X; 061-171-419-166-093; 063-233-206-276-495; 063-264-822-040-939; 064-390-270-497-538; 064-899-287-381-461; 065-010-405-236-060; 066-878-726-698-314; 067-388-422-515-712; 067-687-378-967-147; 068-423-633-404-577; 069-279-651-916-114; 069-378-691-532-645; 069-884-060-370-928; 070-861-953-531-315; 071-000-406-434-892; 071-878-836-294-733; 072-517-347-858-959; 074-802-038-288-062; 075-295-964-398-562; 075-680-330-522-374; 076-606-427-957-287; 077-020-570-398-121; 078-805-700-701-368; 081-332-154-286-785; 082-486-321-205-873; 082-998-769-632-215; 083-077-970-223-632; 083-839-905-717-087; 083-994-925-289-198; 085-297-009-547-285; 085-761-381-038-766; 085-996-428-678-389; 088-228-853-611-529; 091-494-102-726-27X; 093-877-107-426-357; 094-202-467-668-908; 094-965-129-389-290; 096-350-526-333-997; 097-392-624-951-811; 099-159-562-625-026; 100-941-972-230-039; 101-752-490-869-458; 102-416-643-743-594; 105-203-286-325-756; 106-483-971-474-931; 106-589-136-668-770; 106-594-238-329-303; 107-742-762-980-088; 108-900-108-066-520; 109-274-419-044-901; 109-398-219-137-622; 111-095-388-505-557; 112-509-430-933-461; 114-360-691-272-331; 114-687-595-695-224; 116-777-788-267-105; 116-998-854-220-559; 118-413-939-773-79X; 118-556-264-886-611; 120-974-286-046-262; 123-316-465-244-963; 124-976-396-046-655; 126-032-997-840-955; 126-620-123-507-925; 128-670-963-267-467; 129-622-608-502-610; 130-159-949-742-528; 135-586-161-209-507; 138-484-790-851-449; 143-331-336-369-445; 144-688-814-022-656; 145-069-641-743-167; 152-624-301-437-853; 155-278-422-553-375; 167-758-431-744-294; 183-885-597-446-782; 188-386-787-405-848; 195-676-809-594-15X,4,true,cc-by,gold -101-864-752-783-651,Global trends and hotspots in the learning curves of robotic-assisted surgery: a bibliometric and visualization analysis.,2025-05-20,2025,journal article,Journal of robotic surgery,18632491; 18632483,Springer Science and Business Media LLC,Germany,Xianfa Zhang; Jing Wang; Li'na Chen; Huarong Ding,,19,1,223,,Medicine; Visualization; Learning curve; Robotic surgery; Data science; General surgery; Artificial intelligence; Computer science; Operating system,Bibliometric analysis; Learning curve; Robotic-assisted surgery; Visual analysis,Robotic Surgical Procedures/education; Bibliometrics; Humans; Learning Curve; Laparoscopy/education,,,,http://dx.doi.org/10.1007/s11701-025-02391-5,40392339,10.1007/s11701-025-02391-5,,,0,008-325-622-564-115; 011-876-626-607-003; 013-727-830-609-026; 016-307-311-589-949; 017-101-603-584-130; 017-849-128-084-216; 019-667-229-554-710; 020-787-066-824-860; 023-260-844-281-750; 023-868-661-519-223; 025-607-261-319-270; 025-973-441-357-303; 026-845-110-910-864; 028-210-393-857-63X; 029-944-121-925-108; 030-313-528-422-291; 031-507-317-947-364; 032-788-387-345-182; 033-254-871-462-057; 034-697-557-292-677; 038-880-051-335-562; 046-875-608-477-407; 054-326-327-805-839; 056-579-184-238-555; 056-677-565-828-566; 061-322-074-012-325; 063-665-773-869-771; 065-010-405-236-060; 065-422-141-692-206; 069-057-920-327-948; 071-164-850-989-676; 071-561-850-041-374; 072-346-803-269-012; 072-638-467-644-77X; 078-803-538-608-616; 084-378-895-703-227; 087-182-275-180-650; 093-353-807-040-183; 097-921-688-584-10X; 097-944-482-606-934; 099-044-441-074-184; 103-721-290-797-905; 105-006-554-006-75X; 105-487-955-603-184; 113-214-545-949-998; 114-215-879-024-89X; 128-922-079-678-378; 128-928-005-505-455; 132-308-279-448-387; 132-549-954-782-299; 136-720-332-688-76X; 140-588-963-698-250; 141-304-637-251-559; 145-585-048-463-210; 146-275-873-358-341; 148-146-065-616-754; 150-554-515-430-40X; 150-556-075-599-453; 151-629-195-636-483; 152-712-757-393-078; 157-214-158-171-182; 157-259-244-856-531; 159-032-848-860-183; 159-744-240-166-666; 165-373-038-580-174; 165-410-679-427-014; 169-301-922-136-931; 169-541-144-837-434; 172-233-253-254-370; 173-127-443-285-036; 174-564-266-774-139; 179-026-674-775-855; 180-785-222-865-123; 181-245-005-256-478; 181-928-200-869-782; 187-879-445-321-280; 190-533-328-999-914; 191-455-418-207-111; 191-481-470-106-130; 192-147-412-576-102; 192-957-275-668-311; 193-231-160-845-756; 194-983-939-919-286; 196-659-767-250-560,1,false,, -102-150-763-225-921,Current Overview of Scientific Production Associated with Governance in University: A Bibliometric Analysis,2023-08-02,2023,journal article,HUMAN REVIEW. International Humanities Review / Revista Internacional De Humanidades,26959623,Eurasia Academic Publishing Group,,Edgar German Martínez; Elizabeth Sánchez Vázquez; Fernando Augusto Poveda Aguja; Lugo Manuel Barbosa Guerrero; Edgar Olmedo Cruz Mican,"The main objective of this research is to identify the current panorama of scientific production associated with governance in university institutions. A bibliometric analysis was developed in Scopus using R Core Team 2022-Bibliometrix and Vosviewer software. The results highlight the countries with the highest productivity in the topic of study, with the most representative authors favoring the understanding of governance. The main thematic clusters stand out. It recognizes the role of university governance and its migration to direct spaces and the transition from a face-to-face model.",21,1,37,46,,,,,,,http://dx.doi.org/10.37819/revhuman.v21i1.1726,,10.37819/revhuman.v21i1.1726,,,0,002-052-422-936-00X; 013-507-404-965-47X; 036-696-352-616-699; 074-451-013-042-54X; 075-207-977-198-065; 078-997-451-531-36X; 080-045-889-610-939; 097-057-990-480-599; 120-227-368-603-422; 135-751-718-525-918; 151-893-969-019-255; 165-447-911-101-684,0,false,, -102-183-057-185-054,Global research trends in tumor-associated macrophage studies: a bibliometric analysis.,2025-05-09,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Aina Luan; Yipeng Zhang; Lu Yang; Guojing Zhao; Xin Yang,"Macrophages play a critical role in various diseases, including cancer, where their involvement is characterized by a dual nature. There is a growing focus on tumor-associated macrophages (TAMs) in cancer research due to their complex interactions with tumor biology. With the expanding body of research in this area, a retrospective analysis of published articles is warranted to gain insights into evolving trends. This bibliometric study aims to assist researchers in identifying key areas of interest and emerging directions within the field of TAM research.; A bibliometric analysis was performed using the Bibliometrix Package in R Software and CiteSpace software.; The volume of research on TAMs continues to increase, with this study identifying major contributors to the field. The focus of research has shifted from traditional methods, such as flow cytometry and histological techniques, toward single-cell omics approaches, which offer unbiased insights into TAM heterogeneity. Current areas of interest include biomarkers, immune therapies, TAM states, tumor microenvironments, macrophage-targeted agents, and the response of TAMs to therapeutic interventions. These topics are anticipated to remain prominent in the near future.; The study provides an overview of annual publication trends, influential papers, key journals, frequently used keywords, leading authors, and contributing institutions. It also highlights the interdisciplinary evolution of TAM-related research and the connections between these areas of study.; © 2025. The Author(s).",16,1,711,,Data science; Computer science,Bibiliometric study; Citespace; Developmental trends; Hot spots; R software; TAMs,,,the General project of Chongqing Natural Science Foundation under Grant (cstc2021jcyj-msxmX0447),,http://dx.doi.org/10.1007/s12672-025-02473-8,40343509,10.1007/s12672-025-02473-8,,PMC12064514,0,000-403-504-210-375; 002-622-443-674-581; 002-897-994-498-994; 003-941-126-642-388; 004-261-854-911-117; 004-872-631-178-504; 006-973-146-540-202; 009-108-059-749-086; 011-420-792-894-196; 012-690-117-433-739; 015-045-178-668-942; 015-691-817-600-263; 017-193-955-622-920; 017-275-742-246-238; 019-146-400-671-228; 019-374-544-180-000; 020-123-303-081-203; 021-187-404-778-375; 021-680-012-020-732; 021-849-317-851-693; 025-657-249-527-363; 026-645-240-037-120; 027-826-302-375-774; 028-017-499-424-766; 028-953-652-526-104; 029-019-602-768-299; 030-194-216-613-065; 032-590-741-594-701; 032-964-302-127-11X; 036-656-168-693-890; 043-018-693-047-229; 044-572-136-807-509; 044-611-059-549-356; 044-613-717-455-060; 045-242-805-266-469; 045-995-299-664-320; 046-897-454-570-728; 050-278-264-694-940; 054-801-791-497-737; 055-665-908-949-104; 056-203-530-712-788; 062-367-871-619-15X; 063-523-450-468-54X; 064-482-912-103-288; 064-979-192-032-082; 071-748-625-396-785; 072-921-493-141-117; 073-078-811-752-58X; 074-558-653-831-360; 075-068-174-582-242; 075-677-753-939-545; 079-882-444-923-353; 083-674-644-088-653; 087-369-646-763-40X; 088-970-334-316-516; 094-765-036-240-693; 104-236-149-773-098; 106-483-971-474-931; 117-959-558-612-78X; 122-042-403-954-896; 124-399-765-339-14X; 130-053-954-489-920; 135-388-995-999-421; 135-674-631-523-323; 155-276-367-071-47X; 164-697-148-391-758; 169-945-385-953-613,0,true,cc-by,gold -102-705-875-037-091,Tracing two faces of extended visibility: a bibliometric analysis of transparency discussions in social sciences,2022-02-15,2022,journal article,Quality & Quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Oh-Jung Kwon,"Modern governance is the product of constant efforts to make the entire society visible, calculable and manageable. Transparency has emerged as the central ethics to manage public visibility in market and governance. Its celebration or refusal has been associated with technological and political evolution. Using bibliometric analyses of academic literature concerning transparency, this paper traces the interactions of the ethics of transparency with external environments. Guided by historiography and co-occurrence analyses, I map out the major shifts in academic attention and thematic associations related to the ethics of transparency. The modern aspiration of more visibility has been prominent in the finance market, corporate management, public governance, and policy communication. The greater visibility has been associated with accountability, anti-corruption, trust, and participation, as the cure for information asymmetry and power disparity. However, the extended visibility may lessen the human capacity to apprehend reality, which concerns the recent discussions of transparency in higher education, policy communications, and new virtual spaces. By contextualizing the primary themes in transparency discourse, I summarize the three sources of the new risks embedded in extended visibility: the organizational operations decoupled from the intended goals of transparency; the uncovered power relations in the politics of disclosure; and blind reliance on decontextualized digital data.",56,6,4711,4727,Transparency (behavior); Corporate governance; Accountability; Public relations; Sociology; Politics; Visibility; Political science; Economics; Law; Management; Physics; Optics,,,,Ministry of Education,https://www.researchsquare.com/article/rs-466521/v1.pdf?c=1631897291000 https://doi.org/10.21203/rs.3.rs-466521/v1,http://dx.doi.org/10.1007/s11135-022-01334-8,,10.1007/s11135-022-01334-8,,,0,001-030-376-168-623; 013-507-404-965-47X; 013-524-854-219-241; 015-972-003-367-993; 017-059-047-509-570; 025-641-929-232-335; 027-386-317-775-096; 033-203-775-139-575; 034-748-933-167-86X; 036-558-260-031-778; 038-331-503-277-702; 038-938-858-008-991; 040-438-905-073-640; 041-782-519-792-54X; 042-962-759-880-068; 043-624-161-959-155; 047-040-237-229-551; 051-281-417-967-289; 061-557-853-923-28X; 065-952-292-912-155; 068-260-316-694-618; 073-721-344-073-085; 074-872-751-876-170; 079-408-317-286-429; 081-886-625-752-362; 082-502-175-768-359; 084-584-576-792-776; 090-563-522-549-142; 090-963-992-990-357; 100-709-864-053-032; 106-139-920-343-226; 110-675-746-522-264; 113-328-117-971-57X; 119-667-541-178-727; 131-332-197-715-385; 133-160-286-607-487; 139-412-548-519-038; 141-200-607-894-303; 167-053-227-050-017; 183-504-976-422-025,5,true,cc-by,green -102-747-504-831-830,Bibliometric mapping in skin conductance and advertising using the R-package - Bibliometrix,2024-06-26,2024,journal article,Revista de Gestão e Secretariado,21789010,Brazilian Journals,,Diogo Rógora Kawano,"The application of neuroscientific methods to advertising has seen a consistent growth in recent years. This study aimed to map scientific production specifically involving one of these methods, skin conductance, in the context of contemporary advertising in its various forms of action. To this end, a bibliometric analysis was carried out using the international databases Scopus and Web of Science (WoS), with the support of the R language tools Bibiometrix and BiblioShiny. The principal findings are not only the statistical indicators resulting from the research itself, but also the contribution and relevance of the tool in terms of supporting and facilitating the research conducted in the field.",15,6,e3938,e3938,Scopus; Relevance (law); Web of science; Context (archaeology); Field (mathematics); Principal (computer security); Computer science; Data science; Information retrieval; Geography; Political science; Mathematics; MEDLINE; Archaeology; Pure mathematics; Law; Operating system,,,,,https://ojs.revistagesec.org.br/secretariado/article/download/3938/2458 https://doi.org/10.7769/gesec.v15i6.3938,http://dx.doi.org/10.7769/gesec.v15i6.3938,,10.7769/gesec.v15i6.3938,,,0,012-233-972-468-437; 013-507-404-965-47X; 019-895-022-413-296; 040-420-346-047-917; 052-317-491-978-275; 060-382-087-378-324; 100-289-535-131-863; 112-810-864-294-022,0,true,cc-by-nc-nd,gold -102-940-631-330-347,Trends in focal therapy for localized prostate cancer: a bibliometric analysis from 2014 to 2023.,2024-09-27,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Zhi-Yu Xia; Si-Han Zhang; Jian-Xuan Sun; Shao-Gang Wang; Qi-Dong Xia,"Focal therapy, a minimally invasive strategy for localized prostate cancer, has been widely employed in the targeted treatment of localized prostate cancer in recent years. We analyzed 1312 relevant papers from the last decade using Web of Science Core Collection data. Our analysis covered countries, institutions, journals, authors, keywords, and references to offer a multifaceted perspective on the development of this field. The U.S. led in publications, contributing over half of the top 10 institutions. Emberton, M from University College London was the most published and cited author. ""EUROPEAN UROLOGY"" was the top journal by impact factor in 2022. Analysis of references and keywords suggests the prevalence of brachytherapy-related research, while high-intensity focused ultrasound (HIFU), cryotherapy, and irreversible electroporation (IRE) are emerging as new research focuses. Consequently, more high-quality evidence is necessary to evaluate the long-term effectiveness and safety of these novel therapeutic methods.",15,1,472,,Prostate cancer; Medicine; Cancer; Prostate; Oncology; Internal medicine,Bibliometric analysis; Cryotherapy; Focal therapy; High-intensity focused ultrasound; Irreversible electroporation; Prostate cancer,,,,,http://dx.doi.org/10.1007/s12672-024-01387-1,39331332,10.1007/s12672-024-01387-1,,PMC11436610,0,002-052-422-936-00X; 002-710-472-600-768; 004-864-882-234-160; 005-631-902-449-417; 006-868-571-154-148; 008-247-851-650-462; 012-143-083-287-020; 013-507-404-965-47X; 018-682-668-518-913; 019-485-102-276-55X; 019-559-441-051-274; 021-483-000-910-452; 022-633-577-099-980; 023-026-102-567-586; 025-734-646-551-099; 028-689-507-194-094; 034-349-589-330-251; 035-047-092-256-837; 035-394-020-425-503; 036-506-217-270-752; 038-788-757-138-454; 040-484-491-035-747; 040-691-280-312-996; 041-712-232-481-230; 043-978-546-526-295; 046-992-864-415-70X; 049-695-641-787-555; 055-913-193-654-985; 056-219-962-747-761; 056-518-509-398-487; 057-162-032-017-940; 060-447-199-055-612; 064-400-499-357-900; 065-010-405-236-060; 072-262-581-112-264; 072-574-144-251-621; 073-393-109-518-056; 074-473-632-503-437; 075-367-129-129-684; 080-922-345-431-061; 081-235-289-190-313; 086-316-969-366-518; 088-594-500-936-336; 090-476-872-676-699; 093-536-757-400-989; 099-845-354-776-241; 103-748-502-567-555; 105-345-491-404-908; 119-943-348-166-845; 128-163-393-841-909; 131-983-542-935-506; 140-489-308-382-192; 140-642-451-002-517; 141-701-125-896-600; 149-725-961-247-240,0,true,cc-by,gold -102-989-254-624-389,Maritime shipping ports performance: a systematic literature review,2024-06-04,2024,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,L. Kishore; Yogesh P. Pai; Bidyut Kumar Ghosh; Sheeba Pakkan,"AbstractThe maritime sector has evolved as a crucial link in countries' economic development. Given that most of the trade across regions takes place through naval transportation, the performance of the seaports has been one of the focus areas of research. As the publication volume has significantly grown in the recent past, this study critically examines the publications related to the performance of ports for exploring the evolution, identifying the trends of articles, and analyzing the citations covering the publications based on relevant keywords in Scopus database for the period 1975–April 2024. Bibliometric and scientometric analysis was done using R, Python, and VOS software tools. Results indicate the core subject areas as “port efficiency”, “data envelopment analysis” (DEA), “port competitiveness”, “simulation”, “port governance”, and “sustainability,” with ""sustainability"" as the most discussed and highly relevant theme that has evolved in the last five years. Bibliometric data analysis on the subject area, yearly trends, top journals of publications, citation and author analysis, impact analysis, country-wise publication, and thematic analysis with clusters are also performed to outline future research directions. The analysis indicates an exponential rise in publications in recent times and with sustainability-related studies gaining more importance, especially for empirical research on port performance and demands for future empirical research on sustainability and smart port performance subject area. The study's findings are helpful for researchers, academicians, policymakers, and industry practitioners working towards a sustainable maritime port industry.",5,1,,,Business,,,,"Manipal Academy of Higher Education, Manipal",https://link.springer.com/content/pdf/10.1007/s43621-024-00299-y.pdf https://doi.org/10.1007/s43621-024-00299-y,http://dx.doi.org/10.1007/s43621-024-00299-y,,10.1007/s43621-024-00299-y,,,0,000-078-955-021-999; 000-920-014-678-27X; 001-340-090-014-702; 002-052-422-936-00X; 003-284-002-331-45X; 004-256-274-655-448; 004-881-861-074-764; 006-995-735-718-483; 007-889-024-845-969; 008-900-766-676-114; 008-991-776-721-333; 010-322-832-358-932; 011-087-453-725-447; 011-432-245-751-434; 011-604-090-426-108; 013-125-729-485-825; 013-524-854-219-241; 015-279-721-643-707; 015-692-170-714-052; 016-330-082-508-599; 017-802-838-403-041; 022-233-586-493-450; 022-304-790-542-067; 024-034-304-017-722; 024-883-764-608-757; 024-913-756-286-262; 025-180-368-988-669; 031-234-242-078-940; 034-289-510-080-48X; 034-325-647-367-348; 034-837-265-172-536; 034-940-280-008-553; 035-736-397-990-083; 039-635-365-461-307; 040-520-276-396-596; 040-589-303-300-824; 041-367-010-576-74X; 041-751-117-004-895; 041-899-839-540-965; 043-144-723-574-589; 044-406-736-338-570; 045-161-688-240-504; 045-368-114-501-494; 046-058-418-880-473; 046-339-502-950-180; 048-808-128-430-098; 049-320-972-253-856; 049-391-379-302-694; 051-647-739-244-271; 052-322-048-536-364; 052-474-384-470-977; 053-705-485-946-753; 058-860-450-250-918; 059-684-766-735-723; 063-037-920-187-723; 067-425-385-742-317; 068-519-292-579-446; 071-098-881-617-047; 077-477-873-941-590; 078-838-890-477-168; 083-461-462-299-581; 083-535-965-392-605; 086-994-834-459-242; 087-458-209-315-523; 087-775-963-370-689; 088-414-448-215-329; 089-782-422-503-133; 092-288-594-688-642; 092-779-126-537-671; 096-427-035-866-230; 096-830-903-475-687; 099-034-069-380-732; 102-672-197-096-691; 107-975-872-681-115; 110-407-700-257-724; 110-682-650-113-138; 113-724-293-063-663; 114-736-480-429-354; 115-225-814-279-176; 115-364-040-373-053; 116-952-879-606-286; 119-027-873-648-603; 124-004-581-130-852; 135-835-675-972-803; 137-304-982-229-104; 146-238-671-531-895; 149-778-847-144-407; 160-143-195-616-69X; 160-671-580-903-387; 161-861-526-459-995; 169-744-166-857-41X; 181-469-706-464-299; 183-104-446-984-132; 184-013-051-108-229; 185-269-377-800-384; 195-638-802-395-994,3,true,cc-by,gold -103-146-331-025-55X,Bibliometrix Example Datasets [R package bibliometrixData version 0.1.0],2020-12-10,2020,,,,,,Massimo Aria,,,,,,R package; Computer science; Computational science,,,,,https://cran.r-project.org/web/packages/bibliometrixData/index.html https://cran.rstudio.com/web/packages/bibliometrixData/index.html https://cran.wustl.edu/web/packages/bibliometrixData/index.html https://ubuntu.dcc.uchile.cl/web/packages/bibliometrixData/index.html https://cran.r-project.org/web/packages/bibliometrixData/,https://cran.r-project.org/web/packages/bibliometrixData/index.html,,,3112798018,,0,,0,false,, -103-592-398-352-758,Discovering sustainable finance models for smallholder farmers: a bibliometric approach to agricultural innovation adoption,2024-06-04,2024,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Raden Trizaldi Prima Alamsyah; Eliana Wulandari; Zumi Saidah; Hepi Hapsari,"AbstractSmallholder farmers, crucial to global food security, face challenges in sustainable integration into agricultural innovation due to inherent flaws in existing finance models. This research addresses the conspicuous gap in comprehensive reviews on sustainable finance in agriculture through a bibliometric approach. Financial constraints, limited market access, and climate vulnerability plague smallholder farmers, hindering the long-term sustainability of current financial models. This study aims to systematically map the scholarly landscape of sustainable finance models for smallholder farmers, focusing on the adoption of agricultural innovations. A critical knowledge gap exists regarding bibliometric patterns and trends in the adoption of agricultural innovations by smallholder farmers. The study utilizes the RAPID framework for a streamlined and evidence-based bibliometric review, employing RStudio and the bibliometrix-package. The analysis aims to recognize, assess, purge, investigate, and document key themes and emerging patterns in the literature. Noteworthy trends from bibliometric reviews indicate a rise in bibliometric approaches, with VOSviewer as a prevalent tool. This research contributes methodologically by advocating for Scopus as the primary database. The study’s significance lies in informing policy, practice, and research initiatives supporting smallholder farmers. By revealing bibliometric patterns, this study aims to guide the design of innovative and context-specific financial instruments, fostering a more sustainable and inclusive agricultural landscape. In conclusion, this research endeavors to bridge the knowledge gap and provide novel insights at the intersection of sustainable finance and agricultural innovation adoption. The anticipated outcomes will inform the development of tailored financial models, advancing the resilience and productivity of smallholder farmers globally.",5,1,,,Agriculture; Business; Agricultural economics; Industrial organization; Agricultural science; Economics; Geography; Environmental science; Archaeology,,,,University of Padjadjaran,https://link.springer.com/content/pdf/10.1007/s43621-024-00277-4.pdf https://doi.org/10.1007/s43621-024-00277-4,http://dx.doi.org/10.1007/s43621-024-00277-4,,10.1007/s43621-024-00277-4,,,0,002-596-427-175-559; 004-440-410-093-188; 006-750-012-058-578; 011-418-703-920-397; 012-202-626-729-831; 013-507-404-965-47X; 015-933-955-563-084; 017-907-651-464-689; 019-078-230-418-710; 024-063-292-435-128; 024-210-783-295-374; 033-564-270-885-20X; 033-936-535-459-965; 035-470-363-938-804; 035-750-424-130-355; 036-210-818-321-241; 042-033-986-978-958; 049-533-733-821-341; 054-213-083-941-445; 057-226-970-996-268; 058-655-568-406-102; 064-517-525-551-117; 098-526-550-972-691; 101-071-236-662-036; 103-039-672-999-826; 107-564-084-060-936; 132-911-121-330-465; 137-080-825-895-816; 143-252-785-423-093; 160-894-929-080-749; 180-797-813-336-168; 195-529-968-713-822; 195-713-079-780-849,7,true,cc-by,gold -103-634-357-515-509,Coastal impacts of storm surges on a changing climate: a global bibliometric analysis,2022-06-14,2022,journal article,Natural Hazards,0921030x; 15730840,Springer Science and Business Media LLC,Netherlands,Karine Bastos Leal; Luís Eduardo de Souza Robaina; André de Souza De Lima,,114,2,1455,1476,Natural hazard; Storm surge; Flooding (psychology); Climate change; Storm; Coastal flood; Coastal erosion; Scopus; Global warming; Climatology; Environmental science; Geography; Meteorology; Physical geography; Sea level rise; Erosion; Oceanography; Political science; Geology; Psychology; Paleontology; MEDLINE; Law; Psychotherapist,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,,http://dx.doi.org/10.1007/s11069-022-05432-6,,10.1007/s11069-022-05432-6,,,0,003-414-894-005-846; 004-680-452-811-689; 007-393-811-395-718; 007-825-078-366-282; 013-507-404-965-47X; 013-520-110-451-760; 015-271-006-491-891; 016-992-902-840-478; 017-750-600-412-958; 019-439-083-883-356; 020-864-441-987-28X; 021-300-102-541-219; 022-937-587-028-994; 036-182-111-625-254; 037-010-850-537-341; 037-038-204-647-428; 040-890-075-090-994; 041-776-319-991-981; 043-382-069-845-359; 048-478-934-614-984; 048-962-116-958-819; 051-010-780-145-082; 058-016-510-001-961; 060-169-641-767-296; 063-791-214-628-979; 070-059-822-207-525; 074-980-022-466-217; 084-496-329-717-218; 095-780-906-053-819; 098-930-086-009-803; 105-957-186-471-511; 106-373-407-318-631; 107-304-297-992-963; 107-438-746-431-306; 115-677-995-393-29X; 142-529-579-385-471; 158-315-410-246-801; 178-016-403-210-11X,14,false,, -104-080-512-247-95X,Bibliometric Analysis of the Influence of Artificial Intelligence on the Development of Education,2024-06-22,2024,journal article,International Journal of Emerging Technology and Advanced Engineering,22502459,IJETAE Publication House,,Ning Miao; Bo Cai; Qingyue Wang; Xinran Wang; Qianqian Guo,"This study explores the development trends of AI in education through a bibliometric analysis of literature from 2011 to 2021. Using the Biblioshiny toolkit for Bibliometrix in R language, we analyzed titles, authors, abstracts, keywords, citations, and affiliations. The findings reveal research changes and hot directions in AI education, forecasting future developments. While regions like the US and UK have achieved success in AI education, China is integrating AI into teaching disciplines. The rise of AIGC and companies like OpenAI is accelerating AI integration in education, creating opportunities for personalized learning, adaptive education, and intelligent educational management. Collaboration among stakeholders and comprehensive strategies are crucial for successful AI implementation in education",14,2,1,8,China; Computer science; Knowledge management; Engineering ethics; Artificial intelligence; Data science; Political science; Engineering; Law,,,,,,http://dx.doi.org/10.46338/ijetae0224_01,,10.46338/ijetae0224_01,,,0,,0,false,, -104-255-333-000-267,İşletme Alanındaki Liderlik Çalışmalarının Bibliometrix İle Analizi,2024-10-15,2024,journal article,Celal Bayar Üniversitesi Sosyal Bilimler Dergisi,13044796; 21462844,Celal Bayar University Journal of Social Sciences,,Şimal Çelikkol; Nazife Orhan Şimşek; Özgür Aslan,"Liderlik kavramı 1980’lerden bu yana önemini artırarak devam etmektedir. Özellikle işletmelerin başarılarını arttırabilmek adına etkili liderlere olan ihtiyaçları her geçen gün artmaktadır. Etkili liderler; iyi iletişim kurma, ekibini motive etme, sorumlulukları yerine getirme ve devretme, geri bildirimleri dinleme ve sürekli değişen bir işyerinde sorunları çözme esnekliğine sahip nitelikleri taşımaktadır. Bu özelliklere sahip olan liderler işletme performansı üzerinde de büyük etki yaratmakta ve işletmenin karlılığını ve inovatifliğini artırmaktadır. Taşıdığı büyük öneme karşın son yıllarda liderlik üzerine yapılan çalışmaların daha çok kavramsal düzeyde kaldığı görülmektedir. Bu çalışma ikincil verilerden faydalanılarak yapılmış olan bir araştırma makalesidir. Çalışmanın temel amacı; işletme yönetimi alanındaki liderlik çalışmalarının, son dönemde oldukça popüler ve kullanışlı bir Bibliyometri programı olan Bibliometrix ile analizinin yapılmasıdır. Bu analiz sonucunda en üretken ülkeler/yazarlar ve bunlar arasındaki ilişki ağı belirlenmiş ve liderlik konusuyla ilgili eğilimlere dair bulgular elde edilmiştir. Analiz sonucu elde edilen temel hususlar şunlardır; 1980’li yıllardan günümüze değin yayınlar düzenli bir artış eğilimi gösterdiği; Lotka yasasına göre alanın gelişmeye açık olduğu; liderlik kavramı ile ilgili yapılan çalışmalarda en sık tekrar edilen anahtar kelimelerin sırasıyla “performans”, “dönüşümcü liderlik” ve “yönetim” olduğu, liderlik ile ilgili en fazla yayın yapan ülkelerin sırasıyla Amerika Birleşik Devletleri, Çin ve İngiltere olduğu ve atıf sayılarına göre Amerika Birleşik Devletleri’nin diğer ülkelere göre çok belirgin bir üstünlüğü olduğu. Elde edilen bulgular ışığında hem akademik çevrelere hem de işletmelerdeki karar vericilere önerilerde bulunulmaktadır.",,,40,63,Humanities; Physics; Philosophy,,,,,https://dergipark.org.tr/tr/download/article-file/3851973 https://dergipark.org.tr/tr/pub/cbayarsos/issue/89078/1465984,http://dx.doi.org/10.18026/cbayarsos.1465984,,10.18026/cbayarsos.1465984,,,0,013-507-404-965-47X; 033-044-184-587-469,0,true,,green -104-353-071-721-45X,Tourist Taxes and Sustainability,2023-08-10,2023,book chapter,Advances in Public Policy and Administration,24756644; 24756652,IGI Global,,Eva Maria Miranda; Soraia Gonçalves; Laurentina Vareiro,"As the global tourism industry continues to grow, concerns about its impact on the environment and local communities have increased. In response to these concerns, many destinations have implemented tourist taxes as a policy tool to manage the negative impacts of tourism on destinations and promote sustainable tourism. This chapter presents a systematic literature review on the relationship between tourist taxes and sustainability, using the Bibliometrix R software and a content analysis. The aim of this review is to provide a comprehensive analysis of the existing research, identifying gaps in the literature and suggesting areas for future research. The results demonstrate two main categories, concerning demand and supply dimensions. The issue of sustainability is transversal to the articles analyzed, highlighting its evolution in a holistic way and encompassing the economic, social, and environmental pillars.",,,335,349,Sustainability; Tourism; Destinations; Business; Tourist destinations; Marketing; Sustainable tourism; Environmental planning; Environmental economics; Economics; Geography; Ecology; Archaeology; Biology,,,,,,http://dx.doi.org/10.4018/978-1-6684-8592-7.ch015,,10.4018/978-1-6684-8592-7.ch015,,,0,000-082-965-741-457; 000-126-998-492-292; 004-089-340-718-975; 012-487-611-914-948; 013-139-834-434-71X; 023-736-472-481-989; 034-050-858-997-972; 047-794-173-370-847; 052-357-228-880-568; 067-472-271-438-730; 077-512-428-097-468; 084-344-662-856-163; 085-300-287-100-525; 103-820-930-757-025; 123-838-638-667-496; 133-749-753-961-445; 140-687-812-053-416; 161-156-386-041-285; 183-254-867-725-546; 185-063-513-178-355; 193-975-749-660-545,0,false,, -104-401-990-123-374,A scientometric approach to psychological research during the COVID-19 pandemic.,2023-01-23,2023,journal article,"Current psychology (New Brunswick, N.J.)",10461310; 19364733,Springer Science and Business Media LLC,United States,Ali Hamidi; Abdolrasoul Khosravi; Roghayeh Hejazi; null FatemehTorabi; Aala Abtin,"During the COVID-19 pandemic, modern science demonstrated its ability to respond well to the health crisis by publishing useful and reliable information. This disease has also led to an increase in psychological publications in this field. However, most scientometric studies have focused on medical aspects, and social science research has been neglected. Therefore, to fill this research gap, we analyzed the research on COVID-19 in the field of psychology to provide an insight into the perspective, research fields, and international collaborations. Data were collected from the Web of Science database and analyzed using Citespace and Bibliometrix (Biblioshiny). The overall performance of the documents was described, and then keyword co-occurrence and co-authorship networks were visualized. Fifteen main clusters were formed by drawing document co-citation network. The result indicates that Anxiety, mental health, delirium, loneliness, and suicide were important topics for researchers. Considering the special conditions that COVID-19 created for human societies, perhaps one of the most important subjects in the field of health is psychological studies. Using the results of this study, psychology researchers can identify their potential colleagues and research gaps in the subject of Covid-19.",43,1,1,164,Loneliness; Psychology; Mental health; Field (mathematics); Web of science; Coronavirus disease 2019 (COVID-19); Pandemic; Subject (documents); Bibliometrics; Perspective (graphical); Citation; Social science; Data science; Sociology; MEDLINE; Social psychology; Library science; Political science; Psychiatry; Medicine; Disease; Computer science; Mathematics; Pathology; Artificial intelligence; Pure mathematics; Law; Infectious disease (medical specialty),Bibliometrix (Biblioshiny); COVID-19; Citespace; Psychological research; Scientific network; Scientometric,,,,https://link.springer.com/content/pdf/10.1007/s12144-023-04264-2.pdf https://doi.org/10.1007/s12144-023-04264-2,http://dx.doi.org/10.1007/s12144-023-04264-2,36713622,10.1007/s12144-023-04264-2,,PMC9868493,0,000-748-918-183-112; 008-329-649-073-373; 012-966-443-633-263; 013-507-404-965-47X; 017-839-472-387-92X; 018-704-627-836-872; 019-392-373-532-030; 020-395-378-070-698; 023-801-440-677-037; 024-711-410-560-425; 026-888-554-240-400; 030-896-537-629-902; 036-656-168-693-890; 050-976-853-030-147; 053-692-312-251-291; 064-400-499-357-900; 065-303-183-805-73X; 073-454-462-935-703; 075-860-418-889-080; 076-838-906-926-210; 084-240-251-885-131; 084-553-261-689-203; 084-603-158-964-177; 094-048-769-166-089; 102-007-988-019-924; 133-495-109-324-894; 141-200-607-894-303,5,true,,bronze -104-824-849-658-497,Mapping research on biochemistry education: A bibliometric analysis.,2022-01-29,2022,journal article,Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology,15393429; 14708175,Wiley-Blackwell,United States,Mayara Lustosa de Oliveira Barbosa; Eduardo Galembeck,"The purpose of this study was to map the research literature on Biochemistry education, covering the scientific production indexed on the Web of Science over the past 66 years. The open-source Bibliometrix R-package, an R-tool, was used to carry out the bibliometric analysis. Our results describe (1) how many articles were published per year and what is the annual average growth rate; (2) which are the core journals, authors, and publications in the field; (3) which countries and funding agencies contribute most to the development of research in the area; (4) the leading collaborative research and co-citation networks; (5) which articles were the most cited in the past 10 years; and (6) which are the trending topics in the field. Our main contribution is offering insights into the evolution of the field. Also, the use of a quantitative methodological design, which covers a large volume of publications, and could identify possible gaps in the area.",50,2,201,215,Citation; Citation analysis; Library science; Bibliometrics; Field (mathematics); Web of science; Data science; Computer science; Political science; MEDLINE; Mathematics; Pure mathematics; Law,Biochemistry education; bibliometric analysis; bibliometrix,Bibliometrics; Publications,,,,http://dx.doi.org/10.1002/bmb.21607,35092333,10.1002/bmb.21607,,,0,002-504-295-156-848; 004-134-886-938-865; 007-184-566-148-105; 007-661-873-365-977; 013-507-404-965-47X; 014-250-806-667-358; 014-760-386-371-760; 016-242-475-779-242; 020-309-532-368-123; 021-120-139-304-702; 021-369-358-116-924; 025-574-264-133-908; 032-455-392-428-913; 033-855-158-717-679; 034-325-990-698-355; 035-067-051-226-760; 035-461-173-818-743; 037-120-091-101-965; 038-957-003-964-885; 041-070-333-032-520; 043-435-612-548-281; 043-900-969-288-25X; 045-933-330-229-981; 046-329-475-851-363; 051-720-046-820-65X; 057-013-092-634-642; 058-775-344-328-906; 060-473-122-414-188; 079-146-493-130-530; 089-563-867-652-991; 091-543-005-806-946; 092-757-014-786-350; 107-262-715-167-286; 108-746-235-976-874; 121-877-440-381-635; 125-407-869-832-346; 133-525-643-787-594; 134-852-903-471-380; 160-884-199-839-960; 194-110-010-553-18X,10,false,, -104-885-539-440-045,BIBLIOMETRIX PEMBELAJARAN BAHASA DI SEKOLAH DASAR,2023-01-16,2023,journal article,JISPE: Journal of Islamic Primary Education,27745619; 27743934,Institut Daarul Quran,,Muhammad Asip; Likus Likus; Dirhan Dirhan; Voettie Wisataone,"ABSTRACT ; This study aims to see the development of research on language learning in elementary schools. This type of research is included in the type of literature review research. Research data sourced from Scopus. In the Scopus search column, data was found as many as 1,357,373 articles. The data was selected in four stages, namely identification, screening, eligibility, and included so that 26 articles were obtained for data processing. The process of interpreting the data is carried out with the help of R studio type 386.4.1.3. The results obtained are data with three categories of research information, namely authors, document searches, and documents. Based on the results of the study, it can be concluded that language learning in elementary schools is growing rapidly in the USA and the United Kingdom. Meanwhile, the most popular place to publish language learning articles is the journal of speech. For popular vocabulary in research, namely learning and linguistics.",3,2,99,112,Scopus; Vocabulary; Computer science; Publication; Studio; Mathematics education; Natural language processing; Psychology; Artificial intelligence; Linguistics; Political science; Telecommunications; Philosophy; MEDLINE; Law,,,,,,http://dx.doi.org/10.51875/jispe.v3i2.73,,10.51875/jispe.v3i2.73,,,0,,0,false,, -105-145-199-046-123,"Database of Articles used in Mazor & Doropoulos et al. (2018, Nature Ecology and Evolution)",2018-01-01,2018,dataset,Figshare,,,,Tessa Mazor; Christopher Doropoulos; Florian Schwarzmueller; Daniel W Gladish; Nagalingam Kumaran; Katharina Merkel; Moreno Di Marco; Vesna Gagic,"This is a database of journals downloaded from the Web of Science from 2006-2016. These include 21 ecology and conservation journals. R package bibliometrix was used to classify papers into systems (Terrestrial, Marine, Freshwater), and into driver of biodiversity loss (Climate Change, Habitat Change, Invasive Species, Overexploitation and Pollution).
",,,,,Ecology; Database; Geography; Computer science; Biology,,,,,https://figshare.com/articles/Database_of_Articles_used_in_Mazor_Doropoulos_et_al_2018_Nature_Ecology_and_Evolution_/5662072,http://dx.doi.org/10.6084/m9.figshare.5662072,,10.6084/m9.figshare.5662072,,,0,,0,true,cc-by,gold -105-326-764-531-395,Portfolio optimization in the light of factor investment: A bibliometric analysis,,2024,journal article,Accounting,23697393; 23697407,Growing Science,,Pegah Khazaei; Ahmad Makui,"In this study, we attempted to conduct a comprehensive review of the existing and pertinent literature on the topic of factor investment. We performed Scientometric analysis of studies published in reputable finance journals, i.e., The Journal of Portfolio Management, The Financial Analysts Journal, The Journal of Asset Management and others, during the years 2014 to 2023. To obtain the research data for our study, we gathered and examined a collection of 76 bibliographic records sourced from the Web of Science database. This database provided a comprehensive and reliable source of scholarly publications in the field of finance. To analyze the data, we employed Scientometric networks as part of our analytical approach. Scientometric networks allowed us to explore the relationships and connections between different publications, authors, and keywords within the domain of factor investment. To visualize and present the research findings, we utilized the Bibliometrix package for R, a powerful tool specifically designed for bibliometric analysis. This package enabled us to generate insightful visualizations that showcased the key patterns, trends, and interconnections within the literature on factor investment. By employing Scientometric analysis and leveraging the capabilities of the Bibliometrix package, we aimed to provide a comprehensive overview of the existing scholarly research in this field and contribute to the understanding of factor investment.",10,2,55,66,Factor (programming language); Investment (military); Portfolio; Portfolio optimization; Modern portfolio theory; Economics; Econometrics; Financial economics; Computer science; Business; Political science; Politics; Law; Programming language,,,,,,http://dx.doi.org/10.5267/j.ac.2024.1.001,,10.5267/j.ac.2024.1.001,,,0,105-326-764-531-395,1,true,cc-by,gold -105-495-878-632-095,Visualization analysis of breast cancer-related ubiquitination modifications over the past two decades.,2025-03-31,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Yongxiang Li; Yiyang Wang; Yubo Jing; Youseng Zhu; Xinzhu Huang; JunYi Wang; Elihamu Dilraba; Chenming Guo,"Ubiquitination is a type of post-translational modification, referring to the process in which the small molecular protein ubiquitin covalently binds to target proteins under the catalysis of a series of enzymes. The process of ubiquitination is vital in the onset and progression of breast cancer. The use of the ubiquitin-protease system is expected to be a new way to treat human breast cancer. This research aimed to investigate the evolution patterns, key areas of interest, and future directions of ubiquitination in breast cancer via bibliometric analysis.; Research articles on ubiquitination modifications in breast cancer were sourced from the Web of Science Core Collection database and analyzed via Microsoft Excel 2021, Bibliometrix, VOSviewer, and Citespace software for thorough bibliometrics.; From 2005-2024, 1850 English articles published in 405 journals by 1842 institutions/universities from 61 countries were included in the study. Keywords, research fields, co-cited literature and other information were included. Research on ubiquitination modifications has focused on breast cancer, expression, protein, activation, degradation, ubiquitination, phosphorylation, etc. Notably, the keywords that broke out in the past five years have focused on ""triple-negative breast cancer"", ""promotion"", and ""metabolism"". These findings suggest that key areas of current research are metabolism, immunity, survival, and prognosis in triple-negative breast cancer.; Our findings indicate that research on triple-negative breast cancer, as well as its immunological and metabolic aspects, is a burgeoning and promising area. Our work offers valuable guidance and fresh perspectives on the relationship between breast cancer and ubiquitin modification.; © 2025. The Author(s).",16,1,431,,Ubiquitin; Breast cancer; Visualization; Computational biology; Cancer; Data science; Biology; Computer science; Bioinformatics; Genetics; Artificial intelligence; Gene,Bibliometrics; Breast cancer; Protein posttranslational modifications; Triple-negative breast cancer; Ubiquitin; Visualization,,,"Regional Collaborative Innovation Special Project (Science and Technology Aid to Xinjiang Program) (2022E02056); the Regional Collaborative Innovation Special Project (Science and Technology Aid to Xinjiang Program) (2022E02136); the National Natural Science Foundation of China (32260186); the Xinjiang Province Natural Science Foundation (2022D01A140); the Natural Science Foundation of Xinjiang Uygur Autonomous Region Outstanding Youth Science Foundation Project (2024D01E22); the State Key Laboratory of Pathogenesis, Prevention, Treatment of Central Asian High Incidence Diseases Fund (SKL-HIDCA-2024-21)",,http://dx.doi.org/10.1007/s12672-025-02032-1,40163091,10.1007/s12672-025-02032-1,,PMC11958930,0,000-615-670-966-834; 000-891-281-631-441; 002-052-422-936-00X; 007-500-155-247-91X; 009-439-320-020-560; 010-308-932-468-265; 013-211-554-248-756; 019-738-635-825-868; 021-986-748-450-702; 023-404-142-450-847; 025-962-305-062-590; 026-097-611-857-562; 039-076-365-810-310; 050-472-263-714-216; 057-596-942-593-136; 057-987-139-545-221; 058-030-070-399-793; 064-053-603-849-742; 066-682-725-907-570; 078-399-506-633-524; 078-597-376-020-849; 082-442-745-857-387; 089-063-250-270-319; 092-641-595-021-676; 107-483-302-885-238; 113-504-201-214-395; 123-202-581-406-928; 141-770-516-078-794; 146-076-027-620-900; 152-945-454-837-716; 157-262-561-305-589; 173-867-766-183-281; 183-018-366-035-737,1,true,cc-by,gold -105-702-663-277-670,Bibliometric analysis of the global publication activity in the field of relapsing polychondritis during 1960-2023.,2023-08-24,2023,journal article,Clinical rheumatology,14349949; 07703198,Springer Science and Business Media LLC,Germany,Linlin Cheng; Yongmei Liu; Qingqing Ma; Songxin Yan; Haolong Li; Haoting Zhan; Zhan Li; Yongzhe Li,,42,12,3201,3212,Medicine; Relapsing polychondritis; Rheumatology; Internal medicine; Field (mathematics); Family medicine; Medical physics; Library science; Pathology; Computer science; Mathematics; Pure mathematics,Bibliometric analysis; Relapsing polychondritis; VEXAS Syndrome; Web of Science,"Bibliometrics; Skin Diseases, Genetic; Polychondritis, Relapsing; Humans; Databases, Factual; Myelodysplastic Syndromes; Europe",,National Key Research and Development Program of China (2018YFE0207300); National Natural Science Foundation of China Grants (81871302),,http://dx.doi.org/10.1007/s10067-023-06741-2,37620677,10.1007/s10067-023-06741-2,,,0,000-097-977-197-366; 002-052-422-936-00X; 003-580-356-123-814; 005-832-547-769-619; 006-410-312-569-029; 006-812-476-445-462; 013-507-404-965-47X; 013-758-380-086-011; 015-670-425-390-890; 020-272-475-263-838; 022-392-156-414-976; 027-584-546-743-722; 027-878-089-184-964; 031-816-672-344-751; 057-747-521-997-920; 063-751-175-877-350; 064-400-499-357-900; 081-762-311-173-697; 083-854-501-624-082; 089-911-151-750-463; 091-609-517-170-039; 093-357-377-836-154; 098-779-623-374-111; 099-827-514-942-511; 108-047-449-319-105; 143-549-473-768-073; 185-176-418-375-669,7,false,, -105-802-419-834-066,RFID in the Retail sector: A Bibliographic review of the literature,,2022,conference proceedings article,"Proceedings of the 20th LACCEI International Multi-Conference for Engineering, Education and Technology: ""Education, Research and Leadership in Post-pandemic Engineering: Resilient, Inclusive and Sustainable Actions""",,Latin American and Caribbean Consortium of Engineering Institutions,,Giordano Bruno-Valdivia; Gabriel Montoya-del-Solar; Juan Carlos Quiroz-Flores,"All of the companies in the Retail sector, regardless of their size and age, have suffered different problems related to their stock and one solution is the use of radio frequency identification (RFID). Therefore, tracking and understanding the development of the literature on RFID is a key factor in the improvement of supply chain management (SCM). The general objective of this bibliographic review is to understand the behavio r of the researches about the implementation of RFID in the Sco p us database.In order to achieve the objective, the database will be filtered and subsequently analyzed using the VOSviewer software and bibliometrix software.In addition, the results shows the countries with the most publication as well as authors, journals and",,,,,Computer science; Business; Data science,,,,,https://laccei.org/LACCEI2022-BocaRaton/full_papers/FP158.pdf https://doi.org/10.18687/laccei2022.1.1.158,http://dx.doi.org/10.18687/laccei2022.1.1.158,,10.18687/laccei2022.1.1.158,,,0,,0,true,,bronze -105-819-331-565-202,A Thirty-Year Bibliometric Analysis on Servitization,,2021,journal article,"International Journal of Service Science, Management, Engineering, and Technology",1947959x; 19479603,IGI Global,,Luna Leoni; Massimo Aria,"This paper performs a bibliometric analysis of all the servitization literature written during the last three decades, providing its social, intellectual, and conceptual structures. The methodology is based on the R-package bibliometrix for the analysis of co-citation, collaboration, and co-occurrence, applied to all the servitization literature published from 1988 to 2017 indexed in Scopus and WoS databases. Results from the 615 reviewed articles synthesize, consolidate, and improve the existing knowledge on the phenomenon. The study allows the identification of the leading authors, institutions, works, and keywords that compose the servitization publications related to the last three decades, suggesting useful metrics for researchers, new potential entrants, and practitioners. Moreover, offering a definition of servitization, the study provides lexicon consistency to both servitization researchers and practitioners, fostering the constructive accumulation of knowledge on the topic. Lastly, the study provides suggestions for future studies and collaborations opportunities.",12,3,73,95,Business; Bibliometric analysis,,,,,https://www.igi-global.com/article/a-thirty-year-bibliometric-analysis-on-servitization/282039,http://dx.doi.org/10.4018/ijssmet.2021050105,,10.4018/ijssmet.2021050105,3174947253,,0,000-128-345-682-880; 002-831-498-855-452; 003-460-494-460-505; 003-474-754-567-198; 003-521-351-139-702; 004-656-159-002-903; 004-716-237-242-163; 005-985-581-594-522; 009-780-273-848-443; 010-728-969-197-818; 012-583-517-755-012; 012-748-927-246-707; 013-507-404-965-47X; 015-545-122-998-820; 015-692-170-714-052; 017-750-600-412-958; 021-858-966-725-86X; 022-774-738-500-720; 024-115-468-804-161; 028-542-346-751-753; 028-624-842-837-07X; 029-059-223-930-723; 030-586-588-203-262; 032-905-913-152-234; 033-681-269-357-672; 036-659-005-806-663; 037-234-956-149-198; 037-815-640-424-494; 039-707-988-570-673; 043-309-532-527-969; 044-113-214-626-613; 045-405-229-843-216; 046-670-336-645-93X; 047-134-478-431-993; 047-697-021-908-260; 047-807-042-671-666; 048-087-486-562-595; 049-097-807-490-488; 054-344-263-957-321; 054-818-565-070-154; 061-929-854-108-644; 062-013-064-709-177; 064-112-115-116-272; 065-108-368-829-080; 065-405-989-127-787; 067-221-044-302-060; 067-928-684-944-079; 068-627-512-947-174; 070-207-391-303-268; 070-455-764-360-138; 070-991-282-066-330; 071-693-995-776-448; 075-390-695-895-311; 077-265-762-583-386; 080-653-970-351-662; 080-788-112-275-577; 084-286-830-898-838; 084-544-631-309-913; 085-334-417-802-070; 085-721-435-033-842; 085-976-410-058-909; 086-159-133-180-944; 088-928-456-750-792; 089-443-432-595-67X; 094-014-733-175-850; 097-313-384-002-204; 098-972-635-522-833; 103-383-816-633-368; 104-495-326-573-684; 105-247-725-389-490; 106-018-759-199-334; 107-174-491-488-223; 108-607-530-478-675; 111-985-797-859-289; 117-720-219-244-463; 118-773-376-455-200; 122-978-874-692-667; 126-836-473-462-918; 128-217-524-056-953; 128-700-080-469-289; 129-301-781-263-142; 130-057-480-639-007; 139-041-201-686-064; 147-367-100-271-652; 149-112-105-239-625; 149-621-851-087-614; 151-678-990-916-40X; 156-308-983-372-049; 173-228-136-852-97X; 173-488-563-448-999; 176-746-410-871-911; 182-617-345-107-621; 190-030-604-897-072; 194-218-613-646-638,3,false,, -106-317-590-125-494,Bibliometric and visual analysis of chronic stress in cancer research from 2014 to 2024.,2025-01-22,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Zhuheng Wei; Anxia Li; Ling Su; Bo Zhang; Yuanyuan Yan,"In today's fast-paced society, stress has become a widespread phenomenon, garnering increasing attention for its impact on cancer. This study aims to investigate the current status and research hotspots of chronic stress in cancer research from 2014 to 2024, with the goal of providing valuable insights for future studies.; We retrieved 618 articles published between 2014 and 2024 from the Web of Science database and analyzed them using R software, VOSviewer, and CiteSpace.; There is an overall upward trend in chronic stress-related cancer research, with China leading in publications, followed by the United States, India, Australia, and Italy. The journal most cited is Brain Behavior and Immunity. Key themes identified include 'inflammation', 'breast cancer', 'anxiety', 'psychological stress', and 'oxidative stress'. The primary focus of the research is the impact of chronic stress on various cancer types, the underlying molecular mechanisms, and the implications of chronic stress-related treatments on cancer outcomes.; Chronic stress is increasingly recognized as a Carcinogenic factors. This study provides a comprehensive analysis of chronic stress-related cancer research from 2014 to 2024, offering valuable guidance for future research in this field.; © 2025. The Author(s).",16,1,79,,Stress (linguistics); Philosophy; Linguistics,Bibliometric; Cancer; Endocrine; Immune system; Psycho-oncology chronic stress,,,,,http://dx.doi.org/10.1007/s12672-025-01744-8,39843635,10.1007/s12672-025-01744-8,,PMC11754581,0,001-145-718-587-685; 004-661-450-473-715; 005-706-968-934-128; 006-016-911-289-912; 006-106-408-566-934; 006-107-955-164-031; 008-166-376-109-663; 009-429-560-804-63X; 009-614-296-549-872; 011-560-242-336-901; 013-507-404-965-47X; 014-483-523-249-487; 015-285-565-512-190; 015-907-210-424-89X; 016-467-982-034-592; 016-503-748-599-11X; 026-283-035-223-455; 027-361-071-912-941; 029-263-213-526-098; 030-653-301-365-983; 032-433-925-880-148; 033-390-965-701-289; 037-816-810-814-239; 041-394-290-514-896; 042-444-650-006-537; 043-003-342-744-602; 043-546-698-843-557; 044-471-613-729-927; 045-516-143-171-617; 045-993-333-977-461; 048-354-668-601-667; 048-536-159-403-635; 048-867-040-728-703; 052-328-110-471-555; 053-318-431-839-784; 053-706-252-020-380; 059-945-488-187-845; 060-607-110-090-199; 061-529-048-625-409; 061-927-599-280-463; 064-400-499-357-900; 066-677-071-253-638; 076-516-560-558-470; 079-893-679-200-137; 081-438-757-202-283; 085-001-502-383-40X; 092-921-359-373-502; 099-369-779-864-138; 101-387-726-734-697; 107-483-302-885-238; 107-588-831-366-055; 115-639-972-247-233; 119-012-296-819-107; 119-774-840-230-541; 124-085-643-857-81X; 141-873-967-479-783; 148-827-030-688-356; 155-224-758-771-188; 163-986-133-820-374; 165-379-598-158-155,1,true,cc-by,gold -106-483-971-474-931,The scholar's best friend: research trends in dog cognitive and behavioral studies.,2020-11-21,2020,journal article,Animal cognition,14359456; 14359448,Springer Science and Business Media LLC,Germany,Massimo Aria; Alessandra Alterisio; Anna Scandurra; Claudia Pinelli; Biagio D'Aniello,"In recent decades, cognitive and behavioral knowledge in dogs seems to have developed considerably, as deduced from the published peer-reviewed articles. However, to date, the worldwide trend of scientific research on dog cognition and behavior has never been explored using a bibliometric approach, while the evaluation of scientific research has increasingly become important in recent years. In this review, we compared the publication trend of the articles in the last 34 years on dogs’ cognitive and behavioral science with those in the general category “Behavioral Science”. We found that, after 2005, there has been a sharp increase in scientific publications on dogs. Therefore, the year 2005 has been used as “starting point” to perform an in-depth bibliometric analysis of the scientific activity in dog cognitive and behavioral studies. The period between 2006 and 2018 is taken as the study period, and a backward analysis was also carried out. The data analysis was performed using “bibliometrix”, a new R-tool used for comprehensive science mapping analysis. We analyzed all information related to sources, countries, affiliations, co-occurrence network, thematic maps, collaboration network, and world map. The results scientifically support the common perception that dogs are attracting the interest of scholars much more now than before and more than the general trend in cognitive and behavioral studies. Both, the changes in research themes and new research themes, contributed to the increase in the scientific production on the cognitive and behavioral aspects of dogs. Our investigation may benefit the researchers interested in the field of cognitive and behavioral science in dogs, thus favoring future research work and promoting interdisciplinary collaborations.",24,3,541,553,Psychology; Cognition; Psychological research; Perception; World map; Period (music); Science mapping; Behavioral study; Behavioural sciences; Applied psychology,Behavior; Behavioral science; Bibliometrix; Cognition; Dog; Science mapping,Animals; Bibliometrics; Cognition; Dogs; Friends; Humans,,Università degli Studi di Napoli Federico II,https://www.ncbi.nlm.nih.gov/pubmed/33219880 https://europepmc.org/article/MED/33219880 https://link.springer.com/article/10.1007/s10071-020-01448-2 https://link.springer.com/content/pdf/10.1007/s10071-020-01448-2.pdf https://pubmed.ncbi.nlm.nih.gov/33219880/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128826,http://dx.doi.org/10.1007/s10071-020-01448-2,33219880,10.1007/s10071-020-01448-2,3103752269,PMC8128826,0,002-003-831-997-152; 002-052-422-936-00X; 004-401-428-808-127; 004-963-748-961-862; 005-672-230-672-536; 006-461-237-333-939; 009-642-884-897-353; 010-106-637-198-623; 012-284-172-062-973; 013-415-232-904-751; 013-507-404-965-47X; 013-524-854-219-241; 013-804-711-735-464; 014-191-377-945-470; 015-692-170-714-052; 016-698-117-416-252; 016-954-218-318-07X; 017-146-468-093-265; 020-566-150-802-454; 021-382-797-777-739; 021-944-720-672-500; 025-154-101-837-459; 026-416-298-870-917; 027-478-029-407-502; 029-420-167-353-195; 029-862-083-375-096; 031-279-500-238-222; 031-531-051-422-754; 032-380-985-547-762; 036-533-103-548-545; 036-883-207-978-224; 036-996-756-848-220; 039-222-181-198-262; 045-352-339-201-955; 047-623-303-410-434; 049-122-106-678-404; 049-391-379-302-694; 051-647-739-244-271; 051-983-395-904-688; 054-748-967-123-684; 060-110-039-971-60X; 061-995-848-788-212; 064-400-499-357-900; 070-839-756-667-490; 071-878-836-294-733; 081-409-172-149-269; 090-049-552-281-480; 091-578-309-009-014; 098-361-545-084-419; 099-057-090-502-978; 101-752-490-869-458; 106-214-283-883-322; 107-664-417-243-094; 111-261-789-407-991; 117-156-765-701-049; 117-831-125-009-181; 120-974-286-046-262; 122-186-719-759-037; 122-415-544-444-960; 133-692-759-452-874; 151-284-942-084-571; 158-445-877-603-88X; 159-158-775-177-079; 175-274-136-880-786; 178-935-941-875-300,99,true,"CC BY, CC BY-NC-ND",gold -106-622-635-092-376,Harnessing the Power of Technology in Statistics Education: A Comprehensive Bibliometric Study,2024-10-07,2024,journal article,Journal of Advanced Research in Applied Sciences and Engineering Technology,24621943,Akademia Baru Publishing,,Edi Irawan; Rizky Rosjanuardi; Sufyani Prabawanto,"This study aims to conduct a bibliometric mapping of research articles on technology in statistics education. The articles under analysis are those published in English-language journals and indexed in the Scopus database. VOSviewer and Bibliometrix software were employed in the data analysis. The search yielded 59 relevant articles published since 1985, with a 1.84% annual growth rate, an average of 11.02 citations per document, and an average document age of 13.7 years. The publications involved 135 authors from 31 countries, with an average of 2.44 co-authors per document. The research findings revealed the formation of five clusters through networking visualization. Based on the thematic map using Bibliometrix, we identified that ""higher education"" and ""R"" are themes that have shown significant development and are crucial for shaping the technology field in statistics education. This bibliometric analysis provides ideas and references for selecting current, potential, and evolving research themes related to technology in statistics education.",,,108,126,Power (physics); Statistics; Data science; Computer science; Regional science; Sociology; Mathematics; Physics; Quantum mechanics,,,,,https://semarakilmu.com.my/journals/index.php/applied_sciences_eng_tech/article/download/10757/6266 https://doi.org/10.37934/araset.58.2.108126,http://dx.doi.org/10.37934/araset.58.2.108126,,10.37934/araset.58.2.108126,,,0,,0,true,cc-by-nc,hybrid -106-704-031-976-081,Analysis Systematic Literature Review: The Study of HRM Transformation Into Digital-Based GHRM Future Research Agenda,2023-12-30,2023,journal article,West Science Business and Management,2985816x,PT. Sanskara Karya Internasional,,Puspa Dewi Yulianty; Syamsul Hadi Senen,"Eco-friendly human resources can help sustainable business continuity. The current research aims to propose a business model theoretical framework that adapts to the new environment, addresses sustainable goals and gaps in the field, and builds a resilient and agile system for the business ecosystem. To approach the research problem, this study used the R-based Bibliometrix tool. The Scopus database selected and analyzed papers as part of five research steps. Bibliometric tools such as Biblioshiny, VOSviewer, and R Studio have been used to illustrate the findings. This study’s findings highlight several factors that will form the foundation of the proposed model. Green competencies, both natural and acquired, and the requirement to provide green motivation, were identified as important for developing the new business model.",1,5,553,561,Scopus; Agile software development; Knowledge management; Digital transformation; Field (mathematics); Sustainable business; Computer science; Business model; Business transformation; Process management; Human resource management; Management science; Data science; Engineering; Business; Electronic business; Sustainability; Business relationship management; Software engineering; Political science; World Wide Web; Marketing; Ecology; Mathematics; MEDLINE; Pure mathematics; Law; Biology,,,,,https://wsj.westscience-press.com/index.php/wsbm/article/download/517/525 https://doi.org/10.58812/wsbm.v1i05.517,http://dx.doi.org/10.58812/wsbm.v1i05.517,,10.58812/wsbm.v1i05.517,,,0,,4,true,cc-by-sa,hybrid -106-800-745-245-803,Bibliometric Analysis Using Bibliometrix R to Analyze Social Media Use in Political Campaigns,2024-04-29,2024,journal article,The Journal of Society and Media,25801341; 27210383,Universitas Negeri Surabaya,,Dimas Lazuardy Firdauz; Nurdin Sobari,"The role of social media in political campaigns has been a significantly growing phenomenon over the past two decades. The proliferation of this new medium has prompted various evolving research questions aligning with the increasingly progressive practices of digitalizing political campaigning. Considering tracking advancements in this field, the study analyzes the publication trends and patterns in scholarly journals and conference proceedings about the utilization of social media in political campaigns from 2008 to 2023. Employing a qualitative science mapping approach, data are extracted from the Scopus database using keywords related to social media usage in political campaigns during the specified timeframe. Data analysis uses the recent science mapping R package called Bibliometrix, supplemented by network mapping visualization and keyword density analysis using VOSviewer. Findings reveal a notable increase in publications, with the United States emerging as the foremost contributor, demonstrating a more than eighty percent increase since 2011. Our study found that Information Communication and Society is the top publisher, and the University of California has the most institutional affiliations. Twitter is the most researched social media platform, and recent publications focus on using computation-based techniques like machine learning and natural language processing to study social media in political campaigns",8,1,225,254,Politics; Social media; Political science; Sociology; Media studies; Social science; Data science; Computer science; Law,,,,,,http://dx.doi.org/10.26740/jsm.v8n1.p225-254,,10.26740/jsm.v8n1.p225-254,,,0,,0,true,,gold -106-876-828-178-854,Path and future of artificial intelligence in the field of justice: a systematic literature review and a research agenda,2022-08-27,2022,journal article,SN Social Sciences,26629283,Springer Science and Business Media LLC,,Leonardo Ferreira de Oliveira; Anderson da Silva Gomes; Yuri Enes; Thaíssa Velloso Castelo Branco; Raíssa Paiva Pires; Andrea Bolzon; Gisela Demo,,2,9,,,Economic Justice; Scopus; Artificial intelligence; Government (linguistics); Field (mathematics); Sociology; Work (physics); Productivity; Political science; Knowledge management; Public relations; Management science; Computer science; Engineering; Economics; Law; Linguistics; Philosophy; Mathematics; MEDLINE; Pure mathematics; Mechanical engineering; Macroeconomics,,,,,,http://dx.doi.org/10.1007/s43545-022-00482-w,,10.1007/s43545-022-00482-w,,,0,001-383-943-659-263; 003-816-325-730-484; 006-358-623-475-817; 008-549-807-278-548; 008-596-806-385-853; 011-336-473-093-736; 013-507-404-965-47X; 013-661-800-939-586; 016-481-441-845-81X; 017-750-600-412-958; 017-928-617-623-538; 019-997-021-375-66X; 020-281-277-907-545; 020-393-063-391-623; 021-660-844-894-207; 023-254-113-952-556; 027-208-693-667-775; 027-690-220-065-414; 029-987-256-118-215; 030-001-752-181-506; 032-733-069-495-857; 033-540-447-255-064; 036-522-755-078-020; 039-021-033-623-633; 039-110-812-304-847; 044-334-015-238-895; 044-684-173-786-141; 044-965-992-447-697; 045-511-552-872-657; 046-646-182-018-887; 049-526-459-821-828; 050-664-965-270-417; 051-229-302-542-813; 054-661-571-983-942; 055-135-903-020-592; 055-150-388-516-352; 056-129-280-594-332; 057-039-243-414-707; 057-116-455-638-856; 057-332-883-117-180; 057-927-297-299-295; 059-038-898-369-079; 061-538-011-628-803; 062-472-741-581-40X; 062-530-377-496-091; 063-615-552-629-058; 068-017-250-858-172; 070-665-150-453-490; 071-776-316-991-204; 072-242-922-934-242; 072-985-698-337-829; 073-680-309-141-347; 083-566-659-031-977; 089-409-767-761-917; 092-098-851-486-762; 097-957-245-748-798; 100-461-262-249-066; 102-527-805-380-549; 114-556-761-443-816; 119-858-668-655-30X; 119-925-748-106-252; 120-860-810-253-028; 122-561-800-702-638; 122-827-252-276-011; 130-972-518-236-430; 131-388-441-071-87X; 132-270-419-814-342; 134-124-089-501-235; 139-469-611-287-047; 140-122-225-641-311; 140-472-832-513-178; 141-026-656-461-626; 148-394-939-934-802; 162-820-329-568-637; 162-848-535-119-036; 162-862-526-235-44X; 165-536-089-753-112; 172-975-561-287-812; 173-132-197-393-512; 176-733-898-642-350; 180-670-369-288-850; 183-305-796-963-578; 189-735-936-218-384; 192-220-192-265-641; 194-792-414-981-528,7,false,, -107-062-928-111-618,"Bibliometric Analysis for Carbon Neutrality with Hotspots, Frontiers, and Emerging Trends between 1991 and 2022.",2023-01-04,2023,journal article,International journal of environmental research and public health,16604601; 16617827,MDPI AG,Switzerland,Guofeng Wang; Rui Shi; Wei Cheng; Lihua Gao; Xiankai Huang,"The proposal of carbon neutrality is a manifestation of actively responding to global warming and sustainable development, which means all greenhouse gases achieve near-zero emissions. China is also fulfilling its national mission in this regard. This paper collected 4922 documents from the ""Web of Science Core Database"" and used Citespace (6.1.R2 Advanced) and Vosviewer (1.6.18) software and Bibliometrix functions to carry out descriptive statistics on the number of publications, cooperation mechanisms, and keyword hotspots, finding that the literature mainly focused on China's carbon neutrality, carbon emissions, energy efficiency, sustainable development, and other related topics in the past two years. Further, the 2060 carbon neutrality action plan for China is discussed, focusing on the implementation plan and technical route and proposing the corresponding plans. The purpose of this paper is to accelerate the pace of China's achievement of this goal and to provide feasible solutions and pathways to its achievement through insight into global carbon neutrality hotspots and new trends.",20,2,926,926,Carbon neutrality; Greenhouse gas; Pace; China; Neutrality; Action plan; Beijing; Sustainable development; Environmental economics; Computer science; Environmental resource management; Regional science; Environmental science; Political science; Geography; Economics; Ecology; Management; Geodesy; Law; Biology,Citespace; Vosviewer; bibliometric analysis; carbon neutrality; frontiers; hotspots,"Social Conditions; Bibliometrics; Carbon; China; Databases, Factual",Carbon,Science Fund for Creative Research Groups of the National Natural Science Foundation of China; Innovation Centre for Digital Business and Capital Development of Beijing Technology and Business University,https://www.mdpi.com/1660-4601/20/2/926/pdf?version=1673867089 https://doi.org/10.3390/ijerph20020926,http://dx.doi.org/10.3390/ijerph20020926,36673681,10.3390/ijerph20020926,,PMC9859459,0,002-021-456-643-158; 003-370-769-437-47X; 003-643-594-857-712; 006-277-607-091-392; 009-280-785-589-288; 009-910-858-089-430; 009-998-475-707-245; 010-105-332-905-302; 012-957-420-846-974; 016-639-656-891-079; 016-924-080-994-659; 018-467-462-657-262; 020-657-047-117-233; 021-799-624-492-501; 022-383-651-170-361; 025-198-096-962-750; 025-201-400-812-197; 026-372-340-702-158; 029-625-922-086-043; 032-474-777-746-940; 033-104-997-086-583; 033-265-069-716-842; 033-430-679-515-569; 037-092-732-965-638; 041-953-864-261-188; 043-153-525-405-017; 046-891-943-211-120; 046-912-998-707-254; 048-887-985-029-811; 049-728-352-895-080; 064-128-897-801-413; 068-585-319-344-758; 085-900-813-435-704; 088-500-034-077-377; 091-256-018-856-801; 096-789-310-441-949; 103-672-618-460-911; 103-994-385-401-890; 107-701-917-741-591; 111-358-040-689-019; 112-831-028-418-600; 114-214-561-036-407; 114-352-973-897-348; 115-112-385-435-829; 116-339-119-777-116; 119-777-314-465-707; 121-246-555-839-369; 131-214-372-493-47X; 139-320-706-428-88X; 142-063-758-647-113; 145-321-715-971-472; 147-673-669-901-626; 148-263-969-676-429; 152-671-408-596-100; 153-567-041-363-023; 157-138-052-731-995; 157-699-766-442-925; 160-803-401-745-478; 161-454-077-997-094; 167-701-649-051-020; 168-299-648-849-923; 185-713-170-075-494; 188-165-039-846-171; 190-488-553-581-450; 191-830-245-656-606,6,true,,gold -107-197-630-155-958,Research Trends in Communication and Tourism: A Systematic Review and a Bibliometric Analysis,2024-09-06,2024,journal article,Administrative Sciences,20763387,MDPI AG,,Angie Lorena Salgado Moreno; Jorge Alexander Mora Forero; Raquel García Revilla; Olga Martinez Moure,"The aim of this article is to analyze research trends in communication and tourism through a systematic review and bibliometric analysis of the academic literature in order to identify patterns, areas of interest and possible gaps in knowledge, thus contributing to the understanding and development of these interdisciplinary fields. The methodology includes a bibliometric analysis performed with the R Core Team 2022-Bibliometrix software 4.2.3, in addition to the use of VOSviewer software 1.6.20 and a systematic review of the Scopus and Web of Science databases to analyze the most researched topics, authors, their affiliations, countries, most influential publications, keywords and trends. The results of this research are a valuable contribution to the literature and the scientific community by providing a comprehensive and relevant analysis of the current landscape of communication and tourism research. To conclude, this analysis promotes a deeper understanding of the theoretical and conceptual framework of the studies published to date, which is essential for enriching the academic debate on trends in communication and tourism research.",14,9,208,208,Tourism; Bibliometrics; Regional science; Data science; Sociology; Political science; Computer science; Library science; Law,,,,,,http://dx.doi.org/10.3390/admsci14090208,,10.3390/admsci14090208,,,0,007-238-761-267-952; 030-518-219-140-96X; 037-833-056-100-764; 038-230-535-924-780; 042-287-031-696-683; 051-772-876-808-574; 052-418-560-097-205; 055-328-699-838-434; 056-338-913-792-234; 071-306-414-741-130; 073-169-463-640-71X; 076-189-117-511-728; 077-245-049-625-618; 080-399-710-225-482; 082-332-582-260-940; 090-511-002-110-30X; 094-552-390-450-897; 098-827-574-562-047; 101-976-718-193-291; 102-099-100-078-763; 104-212-344-176-751; 104-941-398-861-754; 108-056-558-659-269; 114-541-125-106-921; 116-949-895-647-072; 119-428-839-825-159; 119-779-338-611-982; 128-352-709-610-385; 129-837-995-667-201; 132-546-502-133-112; 132-588-008-965-867; 138-154-322-128-928; 143-271-167-518-777; 149-168-676-839-707; 149-204-723-800-000; 159-524-885-362-643; 160-249-146-996-281; 165-410-161-637-383; 184-305-331-560-345; 186-698-262-397-953; 191-699-991-248-240; 196-314-331-422-073,2,true,cc-by,gold -107-369-610-538-829,СТРУКТУРИЗАЦІЯ СВІТОВОГО НАУКОВОГО ДОРОБКУ ЩОДО РОЛІ ТА МІСЦЯ КІБЕРБЕЗПЕКИ У СИСТЕМІ ЗАБЕЗПЕЧЕННЯ ЕКОНОМІЧНОЇ БЕЗПЕКИ ДЕРЖАВИ,2025-02-28,2025,journal article,Трансформаційна економіка,27868141; 27868133,Publishing House Helvetica (Publications),,В. В. Койбічук; В. В. Боженко,"Дослідження спрямоване на структуризацію світового наукового доробку та системний огляд ролі та місця кібербезпеки у системі забезпечення економічної безпеки держави. Для цього застосовано комплексний бібліометричний та наукометричний аналіз на підґрунті масиву публікацій, отриманих за відповідним пошуковим запитом у базі даних Scopus загальним обсягом 1077, проіндексованих за період з 2004 року по вересень 2024 р. Поєднання сучасних інструментів бібліометричного аналізу (VOSviewer, SciVal), мови програмування R, програмного забезпечення R Studio, пакетів Shiny, Bibliometrix, igraph та їх відповідних бібліотек і функцій дозволило ретельно дослідили отриманий набір публікацій науковців світу, щоб виявити нові тенденції, ключові теми та прогалини в знаннях у означеній темі дослідження. Отже, на першому етапі згенеровано масив публікацій, що індексуються базою даних Scopus та експортовано в форматах csv та BibTex для подальшого аналізу. На другому етапі дослідження сформовано 8 тематичних кластерів у програмному забезпеченні VOSviewer та визначено хронологічну послідовність напрямків досліджень науковців світу щодо тематики ролі кібербезпеки в системі забезпечення економічної безпеки держави. Третім етапом визначено ключові наукові галузі щодо ролі кібербезпеки в системі забезпечення економічної безпеки держави, де вчені, дослідники, аналітики висвітлюють свої напрацювання. Такими галузями є інформатика, інженерія програмного забезпечення, комп’ютерні науки соціальні та повідкові науки. На четвертому етапі побудовано ряд бібліометричних метрик за допомогою програмного забезпечення R Studio, пакетів Shiny, Bibliometrix, igraph, а саме: деревоподібну карту, що відображає частоти використання ключових слів авторів; карту мережі співпраці дослідників за означеною темою; алювіальну діаграму, що відображає еволюцію досліджень ролі та місця кібербезпеки в системі забезпечення економічної безпеки держави; карту, що відображає ступінь розвитку теми та її значущість.",,1 (10),42,50,Psychology,,,,,,http://dx.doi.org/10.32782/2786-8141/2025-10-7,,10.32782/2786-8141/2025-10-7,,,0,013-507-404-965-47X; 043-937-208-344-578; 044-515-954-852-351; 045-829-097-401-123; 091-877-029-844-509; 115-275-552-756-774,0,false,, -107-409-348-318-751,Research characteristics and trends of power sector carbon emissions: a bibliometric analysis from various perspectives.,2022-08-15,2022,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Ke Liang; Wenjie Li; Junhui Wen; Weikun Ai; Jiabin Wang,,30,2,4485,4501,Greenhouse gas; China; Work (physics); Regional science; Thematic analysis; Trend analysis; Political science; Natural resource economics; Environmental science; Geography; Social science; Sociology; Economics; Engineering; Qualitative research; Computer science; Mechanical engineering; Ecology; Machine learning; Law; Biology,Bibliometric analysis; Carbon emissions; Power sector; Research characteristics; Thematic evolution,Humans; Bibliometrics; Carbon; China; England; Explosive Agents,Carbon; Explosive Agents,,,http://dx.doi.org/10.1007/s11356-022-22504-z,35965300,10.1007/s11356-022-22504-z,,,0,001-146-298-821-889; 001-407-368-392-69X; 001-919-870-663-01X; 002-052-422-936-00X; 002-603-754-333-131; 003-025-748-656-721; 003-412-123-825-521; 004-453-803-269-001; 004-617-642-102-291; 007-122-076-530-252; 008-280-566-951-471; 009-133-896-008-546; 009-998-475-707-245; 010-065-762-504-134; 010-776-384-137-576; 013-507-404-965-47X; 013-524-854-219-241; 015-308-949-644-327; 015-889-971-369-390; 020-637-648-744-007; 025-972-111-669-561; 028-166-580-593-048; 029-666-461-422-761; 032-475-383-803-150; 037-542-651-729-129; 039-145-076-078-043; 040-757-880-895-637; 041-527-264-158-425; 045-211-404-879-393; 045-779-062-165-711; 046-393-515-896-053; 047-282-311-584-159; 049-621-093-005-329; 049-730-014-176-756; 054-726-262-980-11X; 055-424-226-760-833; 062-619-287-438-219; 062-908-181-246-826; 064-598-608-187-493; 064-742-234-216-07X; 066-054-253-944-586; 066-987-589-144-157; 069-753-720-326-827; 071-307-393-351-532; 071-335-525-458-330; 074-259-657-840-379; 076-466-381-670-050; 077-351-791-531-201; 079-020-841-796-248; 081-882-978-212-275; 083-427-220-419-65X; 085-210-049-232-291; 086-017-984-152-665; 087-242-971-261-464; 088-707-667-417-43X; 091-862-402-949-965; 093-574-621-958-534; 093-655-017-961-942; 095-258-654-450-233; 103-354-697-725-709; 105-216-934-635-975; 112-067-739-565-761; 114-225-658-759-39X; 124-693-546-192-042; 126-958-877-778-869; 135-735-289-147-84X; 136-486-086-085-61X; 138-856-335-101-827; 146-619-557-258-724; 166-563-901-920-795,3,false,, -107-453-397-377-107,Escenarios de educación no formal en Colombia; potencialidades para la enseñanza de la física,2023-12-19,2023,journal article,Revista de Enseñanza de la Física,22506101; 03267091,Universidad Nacional de Cordoba,,Daniel Alejandro Valderrama; Eliana Yizeth Pedreros Benavides; Marlon Damian Garzón Velasco; Edilberto Suarez Torres,"This research analyses non-formal education settings as potential environments for teaching Physics. The research was structured in two phases. In the first phase, a bibliometric analysis was carried out using RStudio’s Bibliometrix package and data obtained from the Web of Science database of publications that relate these settings and Physics teaching, making it possible to identify the current state of Physics teaching in non-formal contexts. In the second phase, an exhaustive search and follow-up of information on non-formal education settings in Colombia, such as museums, science centres, planetariums, and astronomical observatories, was carried out. The activities conducted in these places were examined and their potential for Physics education was analysed. This study will contribute to a more complete understanding of Physics teaching in non-formal settings and will identify opportunities for improvement in this area.",35,2,75,91,Humanities; Art,,,,,https://revistas.unc.edu.ar/index.php/revistaEF/article/download/43694/43849 https://doi.org/10.55767/2451.6007.v35.n2.43694,http://dx.doi.org/10.55767/2451.6007.v35.n2.43694,,10.55767/2451.6007.v35.n2.43694,,,0,,1,true,cc-by-nc-nd,gold -107-601-960-327-259,"The Impact of Immersive Technologies on Cultural Heritage: A Bibliometric Study of VR, AR, and MR Applications",2024-07-28,2024,journal article,Sustainability,20711050,MDPI AG,Switzerland,Jingru Zhang; Wan Ahmad Jaafar Wan Yahaya; Mageswaran Sanmugam,"This article aims to assist readers in understanding the current status of studies on the subject by providing a descriptive bibliometric analysis of publications on virtual reality (VR), augmented reality (AR), and mixed reality (MR) technologies in cultural heritage. A bibliometric analysis of 1214 publications in this discipline in the Scopus database between 2014 and the beginning of June 2024 was performed. We used VOSviewer and Bibliometrix as the analysis tools in this investigation. The outcome of this study provides a detailed overview of the descriptive bibliometric analysis based on seven categories, including the annual count of articles and citations, the most productive author, the primary affiliation, the publication source, and the subject areas. The contribution of this research lies in offering valuable insights for practitioners and researchers, helping them make informed decisions on the use of immersive technologies, for example, VR, AR, and MR, in the context of cultural heritage.",16,15,6446,6446,Cultural heritage; Virtual reality; Subject (documents); Context (archaeology); Scopus; Descriptive statistics; Augmented reality; Computer science; Data science; Library science; Geography; Human–computer interaction; MEDLINE; Political science; Archaeology; Statistics; Mathematics; Law,,,,,https://www.mdpi.com/2071-1050/16/15/6446/pdf?version=1722132242 https://doi.org/10.3390/su16156446,http://dx.doi.org/10.3390/su16156446,,10.3390/su16156446,,,0,001-706-772-694-462; 002-870-393-077-06X; 003-497-181-443-973; 005-088-627-480-484; 012-962-463-340-806; 013-507-404-965-47X; 015-116-985-461-281; 017-208-069-283-150; 021-774-038-489-157; 023-496-240-792-489; 044-147-544-148-875; 044-808-566-509-681; 046-992-864-415-70X; 047-190-055-913-225; 048-124-307-071-273; 050-609-067-982-963; 055-586-145-169-832; 058-192-846-516-638; 060-558-674-223-681; 076-999-333-413-668; 080-294-980-130-298; 097-902-192-991-082; 099-815-589-857-321; 103-095-650-489-303; 112-743-472-761-480; 126-554-882-363-253; 137-814-968-391-914; 140-515-963-738-884; 141-200-607-894-303; 151-159-477-014-312; 154-395-965-605-377; 178-379-443-924-259; 199-810-681-206-989,15,true,,gold -107-674-663-810-022,Microalgae harvesting by fungal-assisted bioflocculation.,2020-03-27,2020,journal article,Reviews in Environmental Science and Bio/Technology,15691705; 15729826,Springer Science and Business Media LLC,Netherlands,Mateus Torres Nazari; João Felipe Freitag; Vítor Augusto Farina Cavanhi; Luciane Maria Colla,,19,2,369,388,Bioenergy; Biochemical engineering; Renewable energy; Raw material; Biomass; Context (language use); Biorefinery; Bioproducts; Environmental science; Biofuel,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,https://link.springer.com/article/10.1007/s11157-020-09528-y,http://dx.doi.org/10.1007/s11157-020-09528-y,,10.1007/s11157-020-09528-y,3013094071,,0,001-041-528-735-986; 001-468-581-374-780; 001-884-889-910-538; 001-945-719-308-276; 002-265-870-917-696; 002-959-876-139-078; 003-491-664-568-028; 003-561-552-819-137; 005-049-573-292-098; 005-714-134-709-741; 006-742-028-959-960; 007-671-285-543-81X; 007-882-284-784-099; 008-737-341-450-032; 010-594-421-379-535; 010-608-883-119-329; 011-349-074-906-157; 012-595-896-731-683; 013-108-546-700-698; 013-269-301-143-86X; 013-507-404-965-47X; 013-766-151-146-391; 013-779-062-021-346; 014-376-297-911-618; 014-604-176-319-441; 015-080-971-469-678; 015-891-781-866-073; 015-911-443-177-713; 017-154-342-241-760; 020-676-569-452-243; 021-674-377-951-926; 022-172-823-719-585; 023-337-755-036-641; 023-339-506-742-050; 024-006-929-631-652; 024-248-166-133-824; 024-356-905-396-504; 024-438-825-772-281; 024-775-808-390-799; 024-937-319-909-202; 025-179-551-742-757; 026-564-871-306-708; 027-202-040-833-310; 027-278-823-546-917; 027-350-415-249-941; 027-398-017-009-611; 027-676-295-500-416; 027-754-980-947-890; 027-762-246-284-930; 028-288-533-860-102; 028-404-344-894-608; 028-866-174-213-617; 029-721-670-327-575; 030-033-098-245-590; 031-180-072-570-017; 032-171-379-919-174; 032-225-967-216-724; 032-630-048-029-02X; 033-135-362-497-049; 034-069-135-450-607; 034-575-382-391-909; 034-750-212-667-779; 035-202-886-162-039; 037-029-014-620-879; 037-240-101-928-12X; 039-555-807-342-04X; 041-268-235-623-566; 044-616-757-644-273; 045-419-693-421-495; 045-599-667-270-823; 046-345-530-608-05X; 047-081-132-261-169; 047-134-478-431-993; 049-988-226-428-757; 050-327-368-641-358; 054-875-074-663-466; 055-388-015-508-595; 055-633-127-960-101; 057-700-084-864-346; 058-371-538-080-987; 059-264-551-543-336; 059-490-168-859-878; 061-183-412-723-529; 061-511-252-133-561; 063-125-849-380-319; 063-675-659-913-053; 064-757-923-363-712; 065-970-081-342-964; 067-872-398-140-563; 071-545-704-812-791; 072-565-193-393-226; 074-285-869-114-546; 074-853-336-283-42X; 078-818-600-026-425; 078-892-934-209-219; 080-742-299-405-293; 082-124-167-707-833; 083-512-798-370-318; 083-833-523-639-856; 084-066-292-807-497; 086-911-823-487-639; 088-161-155-236-676; 088-692-592-250-401; 090-469-144-484-351; 092-996-644-771-899; 093-820-969-697-938; 094-303-300-104-88X; 095-303-529-160-00X; 099-863-970-135-631; 103-693-326-261-075; 111-731-067-994-243; 117-067-931-237-33X; 118-212-533-834-096; 118-379-295-384-206; 118-484-020-892-513; 120-905-541-446-943; 121-590-707-522-807; 121-625-600-032-338; 122-345-032-029-754; 126-531-384-235-767; 127-843-133-568-603; 132-327-033-517-526; 139-404-092-367-223; 145-101-694-978-987; 145-385-542-730-04X; 148-745-855-551-144; 152-014-688-998-058; 154-203-901-550-283; 154-278-354-628-753; 155-155-186-082-670; 165-536-018-037-485; 167-341-585-593-069; 167-429-103-566-436; 168-886-086-813-780; 175-216-121-357-460; 189-989-403-948-798,45,false,, -107-701-148-381-455,Bibliometric analysis of emerging trends and research foci in brainstem tumor field over 30 years (1992-2023).,2024-04-17,2024,journal article,Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery,14330350; 02567040,Springer Science and Business Media LLC,Germany,Yibo Geng; Luyang Xie; Jinping Li; Yang Wang; Xiong Li,,40,6,1901,1917,Bibliometrics; Web of science; Glioma; Library science; Medicine; Oncology; Psychology; Internal medicine; Computer science; Meta-analysis; Cancer research,Bibliometric analysis; Brainstem tumor; Epigenome; Publication; Web of Science,Bibliometrics; Humans; Brain Stem Neoplasms/therapy; Biomedical Research/trends,,Beijing Municipal Natural Science Foundation (7244344),,http://dx.doi.org/10.1007/s00381-024-06404-w,38630267,10.1007/s00381-024-06404-w,,,0,001-119-214-614-396; 001-581-656-170-286; 002-052-422-936-00X; 010-201-268-982-791; 011-758-271-628-704; 013-507-404-965-47X; 019-880-794-048-047; 026-847-718-063-973; 040-424-324-776-076; 040-640-469-449-689; 057-267-882-810-217; 070-423-948-891-025; 070-673-641-849-182; 078-785-996-541-395; 085-754-672-528-866; 089-455-579-589-109; 108-592-556-235-242; 139-190-208-036-100; 167-373-519-239-682; 172-872-610-914-148; 179-120-323-824-10X,2,false,, -107-810-633-858-731,Corrigendum: Evolution of research trends in artificial intelligence for breast cancer diagnosis and prognosis over the past two decades: A bibliometric analysis.,2023-01-05,2023,journal article,Frontiers in oncology,2234943x,Frontiers Media SA,Switzerland,Asif Hassan Syed; Tabrej Khan,[This corrects the article DOI: 10.3389/fonc.2022.854927.].,12,,1061324,,Breast cancer; Medicine; Oncology; Cancer; Internal medicine,Bibliometrix analysis; artificial intelligence; breast cancer; diagnosis and prognosis; knowledge structures,,,,https://www.frontiersin.org/articles/10.3389/fonc.2022.1061324/pdf https://doi.org/10.3389/fonc.2022.1061324,http://dx.doi.org/10.3389/fonc.2022.1061324,36698386,10.3389/fonc.2022.1061324,,PMC9869868,0,,0,true,cc-by,gold -108-099-387-791-088,Ketamine and its enantiomers for depression: a bibliometric analysis from 2000 to 2023.,2024-04-25,2024,journal article,European archives of psychiatry and clinical neuroscience,14338491; 09401334,Springer Science and Business Media LLC,Germany,Li-Yuan Zhao; Guang-Fen Zhang; Xue-Jie Lou; Kenji Hashimoto; Jian-Jun Yang,,,,,,Ketamine; Antidepressant; Depression (economics); Medicine; Pharmacology; Enantiomer; Psychology; Psychiatry; Chemistry; Anxiety; Organic chemistry; Economics; Macroeconomics,Bibliometric analysis; Depression; Enantiomer; Esketamine; Ketamine; Visualization,,,Natural Science Foundation of Shandong Province (ZR2022MH216); National Natural Science Foundation of China (U23A20421),,http://dx.doi.org/10.1007/s00406-024-01809-9,38662093,10.1007/s00406-024-01809-9,,,0,000-498-759-106-03X; 001-400-651-957-295; 001-406-330-631-953; 002-052-422-936-00X; 002-346-072-752-027; 002-871-431-022-620; 003-463-170-262-952; 007-551-885-219-283; 009-140-086-718-955; 011-782-799-915-63X; 012-723-311-393-564; 014-297-314-018-894; 014-927-111-666-06X; 016-234-499-059-223; 016-302-598-022-612; 017-192-195-452-177; 017-645-987-946-449; 019-053-719-975-888; 021-170-242-140-457; 021-585-087-990-703; 022-840-743-008-944; 024-647-938-832-149; 026-395-112-558-483; 027-688-445-589-312; 028-484-855-976-827; 032-240-610-005-006; 034-014-511-304-622; 035-573-356-868-782; 035-970-641-722-765; 037-958-506-009-650; 038-125-876-516-107; 039-404-992-421-365; 039-517-511-889-153; 040-902-626-282-622; 042-045-434-807-93X; 052-328-446-749-83X; 054-648-605-582-244; 061-820-548-491-084; 063-237-766-728-216; 064-400-499-357-900; 064-903-553-009-419; 065-456-316-183-32X; 068-130-864-271-880; 070-154-280-696-701; 070-599-398-194-485; 072-561-286-865-386; 079-292-695-912-931; 082-507-156-070-265; 082-622-569-564-638; 084-526-025-022-024; 086-975-637-709-608; 088-743-625-385-300; 094-006-155-574-605; 094-025-919-538-377; 100-890-883-518-762; 100-943-077-666-994; 101-157-349-005-646; 102-681-255-746-168; 104-085-727-768-616; 108-659-602-826-03X; 113-011-361-359-467; 138-291-779-739-834; 140-124-823-655-00X; 141-286-564-813-795; 147-665-314-367-161; 168-307-749-526-303; 181-514-743-428-764; 193-986-988-009-972,7,false,, -108-192-100-478-964,A comprehensive review of patternless rapid sand casting using additive manufacturing process by bibliometrix R-tool,2025-02-14,2025,journal article,Discover Applied Sciences,30049261,Springer Science and Business Media LLC,,Yogesh Patil; K. P. Karunakaran; Milind Akarte; Gopal Gote; Yash Gopal Mittal; Avinash Kumar Mehta; Ashik Kumar Patel,"Recently, the metal Additive Manufacturing (AM) process has seen a substantial surge in its usage than other processes, especially indirect routes to obtain metal parts, including Rapid Sand Casting (RSC) using Selective Laser Sintering (SLS) and Binder Jetting (BJ). Further, it is observed that the SLS process has lost importance due to the dominance of the BJ. Thus, literature and commercial AM systems are investigated to determine the causes. This study comprises a Systematic Literature Review (SLR) and Bibliometrix using the Biblioshiny web application for patternless sand mold and core production using RSC. This article aims to obtain research articles via SLR for the SLS and BJ AM process, followed by the Bibliometrix using the Biblioshiny web application. The SLR divided the RSC domain into the AM and the Sand Casting (SC). The authors considered three databases, Scopus, Web of Science (WoS), and EBSCO, and applied the SLR, resulting in 148 articles. Subsequently, the authors analyzed 131 relevant articles via Biblioshiny, which led to valuable insights for future research. The bibliometrix and content analysis revealed seven clusters: RSC processes, its optimization, comparison, multi-material compatibility, environmental impact, mold coating, and applications. The RSC via BJ exhibited dominance in the research and commercial market over SLS, one reason SLS lost its importance. The authors proposed the revival of the SLS AM process by employing affordable CO 2 laser and linear motor flying optics coupled with recent advancements, including incorporating a hybrid AM approach, adaptive slicing, and mold design for AM (DfAM).",7,2,,,Process (computing); Casting; Manufacturing engineering; Process engineering; Manufacturing process; Computer science; Engineering; Materials science; Metallurgy; Operating system; Composite material,,,,,,http://dx.doi.org/10.1007/s42452-025-06522-3,,10.1007/s42452-025-06522-3,,,0,000-810-427-936-516; 001-402-594-965-297; 001-692-567-240-547; 001-784-332-853-056; 002-052-422-936-00X; 003-629-885-974-598; 003-653-377-670-627; 006-136-698-460-480; 006-959-986-280-22X; 010-132-364-131-149; 010-211-022-486-383; 010-326-816-175-229; 010-822-471-399-966; 012-039-595-583-683; 012-368-138-754-122; 013-255-378-815-858; 013-507-404-965-47X; 015-434-075-607-919; 016-018-024-171-856; 017-146-468-093-265; 017-801-519-410-207; 021-504-374-989-02X; 022-035-567-469-28X; 022-673-096-229-517; 023-927-221-065-800; 028-037-650-718-395; 028-344-225-202-443; 028-737-059-707-899; 029-285-149-731-552; 029-420-167-353-195; 029-904-131-849-27X; 031-775-778-366-408; 034-600-428-239-542; 034-682-697-756-814; 035-728-674-021-855; 037-815-640-424-494; 037-837-801-504-186; 037-878-568-926-50X; 038-216-186-506-423; 038-868-939-345-77X; 039-639-818-302-519; 040-550-846-374-899; 040-765-462-668-941; 040-828-042-654-004; 041-226-633-950-444; 042-571-554-522-04X; 042-911-354-037-478; 043-768-320-663-515; 044-327-671-792-08X; 044-902-344-378-031; 045-185-327-581-529; 046-654-776-498-507; 047-209-834-751-760; 049-556-551-870-697; 049-773-133-155-464; 050-927-909-116-505; 052-752-463-682-385; 053-188-703-151-113; 054-818-565-070-154; 055-922-825-805-679; 057-058-693-769-402; 057-313-196-190-438; 060-110-039-971-60X; 060-712-629-510-836; 062-818-780-380-833; 063-249-297-247-820; 064-400-499-357-900; 065-322-525-006-924; 065-905-572-161-593; 066-457-069-832-345; 067-747-827-686-351; 070-898-865-675-131; 071-195-971-460-631; 071-217-881-423-719; 073-205-025-154-83X; 073-807-508-186-121; 073-898-859-786-192; 074-965-505-653-660; 075-231-481-331-23X; 075-745-788-772-679; 078-798-591-550-413; 080-746-733-848-627; 085-082-431-308-644; 085-184-913-763-751; 087-693-352-132-711; 088-355-813-371-067; 088-981-822-391-287; 093-491-086-483-747; 094-145-064-595-929; 096-319-612-264-961; 097-594-281-399-409; 098-453-259-610-340; 099-087-506-022-247; 099-149-841-546-874; 099-719-579-895-594; 099-920-017-935-130; 100-500-180-283-761; 101-752-490-869-458; 104-025-832-819-839; 104-045-811-168-529; 105-416-436-729-983; 107-016-870-691-041; 107-183-130-865-77X; 107-937-543-192-225; 111-805-369-950-691; 112-065-667-681-501; 114-825-644-161-652; 117-369-106-402-562; 117-927-048-185-785; 119-735-332-187-290; 121-695-193-844-710; 122-415-544-444-960; 123-733-761-626-189; 124-374-588-129-49X; 124-622-821-612-059; 124-623-243-879-855; 125-168-323-326-438; 125-358-437-740-060; 128-441-681-851-48X; 128-850-036-603-114; 131-553-991-037-496; 133-043-333-827-093; 133-562-835-384-266; 134-293-584-718-447; 135-243-591-844-418; 135-683-819-347-821; 138-754-850-588-070; 138-964-900-933-043; 140-747-587-503-872; 144-078-283-145-412; 145-691-100-197-095; 147-199-278-864-535; 152-621-354-041-947; 155-775-260-457-539; 157-313-222-147-739; 160-711-143-730-08X; 161-097-531-372-471; 163-573-982-934-813; 164-322-404-778-652; 164-935-640-951-092; 167-999-347-294-670; 168-355-623-567-691; 175-289-683-926-714; 187-398-280-400-88X; 188-772-077-836-26X; 188-976-063-443-208; 189-357-662-304-756; 189-395-294-332-880; 192-898-540-624-436; 194-637-544-110-536,0,true,"CC BY, CC BY-NC-ND",gold -108-240-788-304-092,Analyzing the Bibliometric Trends in Gamification Research using the Bibliometrix R-tool,2024-06-19,2024,book chapter,Level Up! Exploring Gamification's Impact on Research and Innovation,,IntechOpen,,Tibor Guzsvinecz; Annamaria Szelinger,"This study presents a bibliometric analysis of research papers in the field of gamification. With the use of three different databases (PubMed, Scopus, and Web of Science), we analyzed various types of studies in this field using the statistical program package R. After removing possible duplicates, we analyzed a dataset consisting of 18,389 articles regarding gamification research. The results of our study present a detailed view of the gamification landscape, showing the current trends, collaborations, and research interests. Key themes of gamification research include serious games, motivation, and design regarding its multidisciplinary nature. The results also show that there is a need for continued collaboration across disciplines and regions to address complex challenges. Based on the results, valuable insights could be provided for scholars, practitioners, and policymakers who could be interested in this dynamic and multidisciplinary field. This bibliometric analysis provides a deeper understanding of the current state of gamification studies.",,,,,Data science; Computer science,,,,,https://www.intechopen.com/citation-pdf-url/1180541 https://doi.org/10.5772/intechopen.1005580,http://dx.doi.org/10.5772/intechopen.1005580,,10.5772/intechopen.1005580,,,0,005-638-250-129-638; 010-065-762-504-134; 013-507-404-965-47X; 013-772-772-516-480; 021-886-442-806-990; 025-302-119-966-613; 029-630-611-756-819; 029-658-473-372-829; 033-928-141-564-105; 036-131-495-164-791; 037-426-339-293-65X; 039-825-832-643-87X; 040-414-260-726-221; 042-966-861-134-211; 046-310-749-963-638; 051-607-610-902-126; 057-654-040-328-176; 062-568-232-120-804; 064-742-234-216-07X; 077-661-504-849-027; 089-241-293-864-917; 104-151-927-001-666; 117-925-608-846-280; 119-271-182-035-239; 137-812-871-269-868; 141-174-944-717-336; 145-637-873-756-47X; 161-462-390-137-429; 181-642-544-617-518; 183-621-871-088-318,0,true,cc-by,hybrid -108-372-974-648-256,"Indagación, modelización y pensamiento computacional: Un análisis bibliométrico con el uso de Bibliometrix a través de Biblioshiny",,2024,journal article,Revista Eureka sobre Enseñanza y Divulgación de las Ciencias,1697011x,Servicio de Publicaciones de la Universidad de Cadiz,Spain,Alejandro Carlos Campina López; Antonio Alejandro Lorca Marin; María Ángeles de las Heras Pérez,"As its first objective, this article carries out a bibliometric analysis aimed at serving as a guide on how to conduct bibliometrics using Biblioshiny, an interface of the Bibliometrix statistical software. To achieve this, a search has been used as an example, detailing the methodology, procedures, and strategies employed to address research questions and, as a secondary objective, to understand which works jointly develop Computational Thinking, Modelling, and Inquiry in the field of sciences. By utilizing quantitative statistical methods for data visualization, the intention is to identify the most relevant authors and journals, along with their impact indices, as well as the main thematic areas and their temporal evolution, in order to gain insights into what is being studied and how in this field. The results indicate that modelling is one of the salient themes among the 31 selected articles, accomplished through research, construction, and design of simulations in digital environments using block-based programming. Keywords: bibliometrics; bibliometrix; modelling; computational thinking; inquiry; science education learning.",21,1,,,Salient; Thematic map; Visualization; Bibliometrics; Field (mathematics); Statistical analysis; Computer science; Thematic analysis; Data science; Sociology; Geography; Social science; Library science; Qualitative research; Cartography; Mathematics; Artificial intelligence; Statistics; Pure mathematics,,,,,https://rabida.uhu.es/dspace/bitstream/10272/23525/2/1102_Campina.pdf https://hdl.handle.net/10272/23525,http://dx.doi.org/10.25267/rev_eureka_ensen_divulg_cienc.2024.v21.i1.1102,,10.25267/rev_eureka_ensen_divulg_cienc.2024.v21.i1.1102,,,0,,0,true,cc-by-nc,gold -108-939-698-378-193,"One hundred years of neurosciences in the arts and humanities, a bibliometric review.",2023-11-09,2023,journal article,"Philosophy, ethics, and humanities in medicine : PEHM",17475341,Springer Science and Business Media LLC,United Kingdom,Manuel Cebral-Loureda; Jorge Sanabria-Z; Mauricio A Ramírez-Moreno; Irina Kaminsky-Castillo,"Neuroscientific approaches have historically triggered changes in the conception of creativity and artistic experience, which can be revealed by noting the intersection of these fields of study in terms of variables such as global trends, methodologies, objects of study, or application of new technologies; however, these neuroscientific approaches are still often considered as disciplines detached from the arts and humanities. In this light, the question arises as to what evidence the history of neurotechnologies provides at the intersection of creativity and aesthetic experience.; We conducted a century-long bibliometric analysis of key parameters in multidisciplinary studies published in the Scopus database. Screening techniques based on the PRISMA method and advanced data analysis techniques were applied to 3612 documents metadata from the years 1922 to 2022. We made graphical representations of the results applying algorithmic and clusterization processes to keywords and authors relationships.; From the analyses, we found a) a shift from a personality-focus quantitative analysis to a field-focus qualitative approach, considering topics such as art, perception, aesthetics and beauty; b) The locus of interest in fMRI-supported neuroanatomy has been shifting toward EEG technologies and models based on machine learning and deep learning in recent years; c) four main clusters were identified in the study approaches: humanistic, creative, neuroaesthetic and medical; d) the neuroaesthetics cluster is the most central and relevant, mediating between creativity and neuroscience; e) neuroaesthetics and neuroethics are two of the neologism that better characterizes the challenges that this convergence of studies will have in the next years.; Through a longitudinal analysis, we evidenced the great influence that neuroscience is having on the thematic direction of the arts and humanities. The perspective presented shows how this field is being consolidated and helps to define it as a new opportunity of great potential for future researchers.; © 2023. The Author(s).",18,1,17,,Creativity; Field (mathematics); The arts; Multidisciplinary approach; Toolbox; Psychology; Perception; Beauty; Cognitive science; Computer science; Data science; Sociology; Social science; Aesthetics; Visual arts; Art; Social psychology; Neuroscience; Mathematics; Pure mathematics; Programming language,Educational innovation; Higher Education; Humanities; Neuro-Arts; Neuroaesthetics; Neurosciences; R programming; Scopus,Humanities; Cognition; Art; Neurosciences; Creativity,,Instituto Tecnológico y de Estudios Superiores de Monterrey (E061 - EHE-GI02 - D-T3 - E),https://peh-med.biomedcentral.com/counter/pdf/10.1186/s13010-023-00147-3 https://doi.org/10.1186/s13010-023-00147-3,http://dx.doi.org/10.1186/s13010-023-00147-3,37946225,10.1186/s13010-023-00147-3,,PMC10633938,0,000-204-028-513-620; 000-476-175-413-258; 003-048-433-590-15X; 004-248-790-445-64X; 007-677-217-960-678; 009-050-633-418-398; 012-439-088-960-635; 017-661-105-631-323; 023-211-156-419-268; 031-367-946-370-770; 031-526-887-447-859; 033-661-563-813-466; 034-285-697-142-83X; 035-703-070-475-96X; 036-146-835-811-732; 038-989-662-768-032; 039-315-263-446-365; 043-397-865-311-587; 043-725-917-616-64X; 044-473-745-455-162; 044-808-566-509-681; 047-962-085-362-740; 048-049-090-195-031; 049-391-379-302-694; 051-647-739-244-271; 055-206-680-348-00X; 055-560-837-436-166; 063-005-402-736-909; 063-050-462-225-169; 065-678-790-623-357; 071-793-495-530-466; 072-858-550-556-169; 082-957-456-794-634; 085-233-442-361-593; 098-890-997-396-302; 106-725-197-464-361; 108-851-952-765-863; 110-742-040-134-873; 110-830-582-578-794; 112-877-007-027-540; 114-007-560-018-803; 141-087-854-121-445; 141-371-571-099-557,5,true,"CC BY, CC0",gold -108-964-544-776-839,Pyrrolizidine alkaloids in tiger moths: trends and knowledge gaps,2024-08-24,2024,journal article,Chemoecology,09377409; 14230445,Springer Science and Business Media LLC,Switzerland,Isabel Lopez-Cacacho; Ivone de Bem Oliveira; Amanda Markee; Nicolas J. Dowdy; Akito Y. Kawahara,,34,4,163,173,Pyrrolizidine; Biology; Tiger; Erebidae; Chemical ecology; Herbivore; Ecology; Sex pheromone; Chemical defense; Zoology; Botany; Lepidoptera genitalia; Computer security; Computer science,,,,"University of Florida, Biology Department, Davis Graduate Fellowship in Botany",,http://dx.doi.org/10.1007/s00049-024-00411-8,,10.1007/s00049-024-00411-8,,,0,001-808-124-852-976; 002-052-422-936-00X; 004-108-682-623-870; 004-212-523-734-741; 004-356-393-215-953; 005-708-304-337-880; 007-288-114-446-458; 007-382-425-497-448; 008-416-808-273-213; 008-635-366-227-526; 009-612-782-513-577; 009-974-351-360-968; 010-088-926-761-287; 010-235-258-895-665; 011-248-752-759-924; 011-315-723-898-965; 012-683-812-125-249; 013-507-404-965-47X; 013-945-947-587-137; 014-147-882-855-830; 016-305-117-891-280; 017-141-481-040-093; 019-353-176-967-826; 021-465-578-012-318; 022-746-813-636-41X; 027-978-953-475-894; 030-895-760-411-290; 033-036-306-685-076; 033-588-877-076-173; 034-322-602-150-264; 034-685-669-175-151; 035-335-035-127-701; 038-728-011-973-360; 039-207-772-740-898; 042-930-242-729-967; 046-447-060-092-200; 047-957-899-465-195; 048-226-410-685-49X; 048-383-660-468-42X; 048-874-917-922-568; 049-566-202-728-210; 051-748-589-654-664; 064-019-515-180-832; 064-373-860-087-964; 067-000-170-741-225; 070-022-547-762-778; 073-275-262-197-968; 082-359-065-738-280; 086-254-202-746-282; 087-942-238-771-936; 108-143-621-564-576; 112-723-506-603-459; 120-565-537-818-54X; 120-610-687-793-587; 122-298-140-113-313; 122-415-544-444-960; 125-276-986-169-507; 126-331-019-648-92X; 129-068-529-875-499; 149-128-883-504-268; 180-916-055-626-260; 192-655-701-205-288,0,false,, -108-971-030-416-938,Visualize the time dynamics and research trends of macrophage associated periodontitis research from 2004 to 2023: Bibliometrix analysis.,2024-11-15,2024,journal article,Medicine,15365964; 00257974,Ovid Technologies (Wolters Kluwer Health),United States,Hu Zheng; Yuhang Cai; Keyi Liu; Junwei Xiang; Wenjia Han; Yuanyin Wang; Ran Chen,"Macrophages play an important role in the symptoms and structural progression of periodontitis, and are receiving increasing attention. In recent years, research has shown significant progress in macrophage associated periodontitis. However, there is still lack of comprehensive and methodical bibliometric analysis in this domain. Therefore, this research aims to describe the state of the research and current research hotspots of macrophage associated periodontitis from the perspective of bibliometrics.; This study collected and screened a total of 1424 articles on macrophage associated periodontitis retrieved between 2004 and 2023 from Web of Science Core Collection database. Use Citespace (6.1. R6), Bibliometrix-R (4.1.3), VOSviewer (1.6.19), and Graphpad Prism8 software to analyze and plot countries/regions, institutions, journals, authors, literature, and keywords to explore the research hotspots and development trends of macrophage associated periodontitis.; After analysis, the amount of macrophage associated periodontitis publications has been rising consistently over time, with China having the most publications (29.32%). 3 countries accounted for 65.57% of the total publications: the United States, China, and Japan, occupying a dominant position in this research field. China publications have the fastest growth rate and played a driving role. The most productive institution is the Sichuan University in China. Journal of Periodontal Research is highly popular in the field of macrophage associated periodontitis, with the highest number of publications. Grenier, Daniel is the most prolific author. Inflammation and Bone Loss in Periodontal Disease are the most cited literature. ""Biological pathogenic factors,"" ""immune regulation,"" ""mechanism research,"" ""susceptibility factor research,"" ""pathological processes and molecular correlation,"" ""pathological characteristics,"" ""inflammatory response"" are the main keyword groups in this field.; This study systematically analyzes and describes the development process, direction, and hotspots of macrophage associated periodontitis using bibliometric methods, providing a reference for future researchers who continue to study macrophage associated periodontitis.; Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.",103,46,e40450,e40450,Periodontitis; Medicine; Dental research; China; Bibliometrics; Web of science; Dentistry; Internal medicine; Library science; Meta-analysis; Political science; Computer science; Law,,Bibliometrics; Humans; Periodontitis/epidemiology; Macrophages/immunology; Biomedical Research/trends; China/epidemiology,,"Research Fund of Anhui Institute of translational medicine (2022zhyx-C86); 2022 Disciplinary Construction Project in School of Dentistry, Anhui Medical University (2022xkfyhz01)",,http://dx.doi.org/10.1097/md.0000000000040450,39560581,10.1097/md.0000000000040450,,PMC11576026,0,000-318-776-793-838; 000-341-865-459-511; 000-503-019-423-068; 001-829-847-842-686; 004-473-066-773-619; 006-757-039-378-59X; 007-498-254-504-248; 008-614-830-270-438; 010-130-842-872-373; 013-145-657-415-518; 013-877-703-425-463; 014-941-691-935-06X; 016-499-550-753-514; 016-640-157-690-094; 016-722-507-218-996; 016-826-248-754-730; 017-054-467-885-617; 017-455-548-911-095; 018-163-791-237-717; 019-395-579-540-101; 020-405-771-567-840; 020-926-769-750-607; 021-957-767-142-964; 022-973-170-641-96X; 024-716-446-286-889; 025-277-947-572-458; 027-292-365-542-425; 027-908-413-645-57X; 029-832-552-818-367; 030-366-783-625-757; 030-602-126-991-310; 032-194-757-354-986; 032-334-266-220-571; 033-306-625-481-211; 036-368-272-014-337; 041-376-677-359-166; 042-396-437-605-65X; 043-904-816-782-503; 044-613-955-454-573; 045-962-288-326-827; 048-486-091-886-841; 050-396-273-453-492; 051-268-143-483-984; 051-702-327-217-524; 057-667-823-374-358; 058-986-825-757-816; 061-970-449-683-316; 067-142-834-911-957; 070-324-988-630-862; 072-191-146-155-862; 074-135-436-420-747; 077-405-330-472-14X; 078-390-807-231-149; 078-547-499-169-840; 078-924-264-437-709; 080-329-001-313-97X; 086-771-614-669-020; 087-182-348-730-378; 094-599-227-028-58X; 097-153-893-155-866; 098-720-250-502-961; 100-817-480-267-718; 109-341-708-381-805; 109-591-369-068-604; 110-082-236-052-756; 117-655-785-749-986; 125-474-260-720-66X; 133-006-024-104-155; 133-237-927-940-208; 141-889-234-297-620; 148-699-357-420-243; 164-457-405-102-126,0,true,"CC BY, CC BY-NC",gold -109-161-368-191-045,Bibliometric analysis of digital transformation on organization design,2025-01-01,2025,journal article,Anali Ekonomskog fakulteta u Subotici,03502120; 26834162,,,Katarina Božić,"Digital transformation has become a key driver of change in modern organizations, reshaping their design and way of functioning. This paper aims to investigate how digitalization has impacted organizations and their organizational design, using a bibliometric approach to analyze research trends in this area. Using the Bibliometrix software package in the R programming language, bibliographic data analysis was performed in order to identify the most influential authors, key topics and future research directions. The study analyzed a dataset of 175 publications in English from the period 2000-2023, sourced from Web of Science Core Collection database, focusing on research articles discussing digital transformation and organizational design. Bibliometrix application was used to perform the bibliometric analysis, which included co-citation, keyword analysis, and thematic mapping to reveal core trends and influential papers in the literature. The study reveals that digital transformation significantly alters organizational structure and role distribution, often decentralizing power and increasing flexibility within companies. These findings align with theories on dynamic capabilities and suggest that further research could focus on how digital transformation supports agility in organizational design, providing practical insights for adapting organizations to digital era demands. Future research on the impact of digital transformation on organizational design could focus on artificial intelligence integration, digital skill requirements, hybrid structures, blockchain technology, as well as challenges and strategies for managing data security and privacy.",,00,52,52,Transformation (genetics); Digital transformation; Computer science; World Wide Web; Chemistry; Biochemistry; Gene,,,,,,,,,,,0,,0,true,cc-by,gold -109-205-258-298-564,A bibliometric review of oncolytic virus research as a novel approach for cancer therapy.,2021-05-12,2021,journal article,Virology journal,1743422x,Springer Science and Business Media LLC,United Kingdom,Amir Sasan Mozaffari Nejad; Tehjeeb Noor; Ziaul Haque Munim; Mohammad Yousef Alikhani; Amir Ghaemi,"Background In recent years, oncolytic viruses (OVs) have drawn attention as a novel therapy to various types of cancers, both in clinical and preclinical cancer studies all around the world. Consequently, researchers have been actively working on enhancing cancer therapy since the early twentieth century. This study presents a systematic review of the literature on OVs, discusses underlying research clusters and, presents future directions of OVs research. Methods A total of 1626 published articles related to OVs as cancer therapy were obtained from the Web of Science (WoS) database published between January 2000 and March 2020. Various aspects of OVs research, including the countries/territories, institutions, journals, authors, citations, research areas, and content analysis to find trending and emerging topics, were analysed using the bibliometrix package in the R-software. Results In terms of the number of publications, the USA based researchers were the most productive (n = 611) followed by Chinese (n = 197), and Canadian (n = 153) researchers. The Molecular Therapy journal ranked first both in terms of the number of publications (n = 133) and local citations (n = 1384). The most prominent institution was Mayo Clinic from the USA (n = 117) followed by the University of Ottawa from Canada (n = 72), and the University of Helsinki from Finland (n = 63). The most impactful author was Bell J.C with the highest number of articles (n = 67) and total local citations (n = 885). The most impactful article was published in the Cell journal. In addition, the latest OVs research mainly builds on four research clusters. Conclusion The domain of OVs research has increased at a rapid rate from 2000 to 2020. Based on the synthesis of reviewed studies, adenovirus, herpes simplex virus, reovirus, and Newcastle disease virus have shown potent anti-cancer activity. Developed countries such as the USA, Canada, the UK, and Finland were the most productive, hence, contributed most to this field. Further collaboration will help improve the clinical research translation of this therapy and bring benefits to cancer patients worldwide.",18,1,98,98,Virology; Library science; Molecular therapy; Cancer therapy; Research areas; Rapid rate; Oncolytic virus; Biology,Bibliometric; Cancer; Dynamic co-citation; Oncolytic virus; Virotherapy,"Bibliometrics; Databases, Factual; Humans; Neoplasms/therapy; Oncolytic Virotherapy; Oncolytic Viruses",,,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113799 https://virologyj.biomedcentral.com/articles/10.1186/s12985-021-01571-7 https://europepmc.org/article/MED/33980264 http://pubmed.ncbi.nlm.nih.gov/33980264/ https://link.springer.com/content/pdf/10.1186/s12985-021-01571-7.pdf https://pubmed.ncbi.nlm.nih.gov/33980264/ https://www.ncbi.nlm.nih.gov/pubmed/33980264,http://dx.doi.org/10.1186/s12985-021-01571-7,33980264,10.1186/s12985-021-01571-7,3160748712,PMC8113799,0,001-901-412-783-967; 002-164-906-190-765; 002-943-545-566-589; 003-043-307-730-059; 003-273-587-266-097; 003-822-452-768-865; 004-205-640-736-978; 007-789-746-144-744; 008-381-459-494-386; 008-824-637-788-505; 010-796-076-923-303; 011-689-647-761-700; 011-772-290-696-762; 011-858-037-489-345; 012-077-341-869-777; 012-536-329-278-077; 012-610-174-638-084; 013-507-404-965-47X; 016-698-050-417-727; 017-848-964-627-285; 018-453-014-574-044; 018-818-596-971-62X; 018-831-406-937-858; 019-159-967-890-889; 019-925-039-200-558; 021-187-404-778-375; 023-372-334-754-737; 025-496-095-528-667; 027-716-862-971-411; 028-548-761-143-402; 029-186-783-561-729; 032-550-561-405-399; 033-043-268-941-213; 033-958-253-243-733; 035-054-297-323-437; 037-904-678-808-21X; 038-403-493-970-086; 038-446-868-055-096; 040-000-552-028-951; 041-790-465-823-928; 042-254-971-502-876; 042-719-805-570-571; 044-604-651-744-921; 044-915-430-903-931; 051-575-856-809-93X; 052-247-798-669-986; 052-315-633-758-86X; 052-607-188-746-506; 053-248-385-985-711; 053-836-698-352-983; 054-818-565-070-154; 058-957-880-959-83X; 060-476-365-620-940; 060-682-842-922-122; 061-615-935-439-224; 065-561-551-238-647; 068-626-831-948-823; 070-004-429-006-26X; 071-839-765-091-389; 074-131-517-942-231; 074-186-914-087-273; 074-299-656-637-738; 077-528-432-594-48X; 077-735-946-796-03X; 079-013-137-440-357; 080-955-815-594-377; 081-317-964-399-743; 081-947-876-364-686; 083-002-671-187-313; 084-467-956-950-702; 089-686-060-927-894; 089-716-398-629-338; 093-153-992-054-299; 094-526-355-474-923; 095-979-168-639-743; 096-553-553-652-758; 096-695-594-113-746; 099-378-375-958-968; 108-268-350-629-591; 111-743-459-186-702; 115-309-257-991-328; 118-763-868-823-744; 120-038-077-612-326; 127-805-672-908-534; 128-897-283-205-074; 135-139-321-116-621; 138-036-512-631-113; 154-399-282-361-201; 161-213-338-653-760; 161-325-997-204-746; 171-779-087-610-971; 183-773-623-851-014,11,true,"CC BY, CC0",gold -109-300-499-357-188,Micropollutants in wastewater treatment plants: A bibliometric - bibliographic study,,2024,journal article,Desalination and Water Treatment,19443986; 19443994,Elsevier BV,United Kingdom,Yahya El Hammoudani; Fouad Dimane; Khadija Haboubi; Chaimae Benaissa; Lahcen Benaabidate; Abdelhak Bourjila; Iliass Achoukhi; Mustapha El Boudammoussi; Hatim Faiz; Abdelaziz Touzani; Mohamed Moudou; Maryam Esskifati,"The increasing global chemical consumption has led to widespread environmental degradation with micropollutants, sparking deep concerns for both aquatic life and human health. These contaminants, encompassing a range of hydrophobic and hydrophilic substances, can negatively impact the environment at very low concentrations. This investigation, covering literature from 2000 to 2023 extracted from the Scopus database and analyzed using the 'bibliometrix' tool in R, aims to augment our understanding and highlight progress in remediation strategies. Through data visualization with 'biblioshiny' and 'VOSviewer', we observed an increased research interest in the destiny of micropollutants within Wastewater Treatment Plants (WWTPs). The research underscores notable improvements in treatment methods that promise greater efficiency in removing pollutants. It stresses the importance of continuous technological innovation, cross-sector collaboration, and global policy reforms to effectively tackle micropollutant challenges, leading to a cleaner environment and better health outcomes.",317,,100190,100190,Wastewater; Sewage treatment; Environmental science; Bibliometrics; Library science; Computer science; Environmental engineering,,,,,,http://dx.doi.org/10.1016/j.dwt.2024.100190,,10.1016/j.dwt.2024.100190,,,0,000-643-507-323-650; 001-591-935-031-720; 002-119-652-221-986; 002-703-675-020-936; 003-602-642-860-326; 004-259-259-509-956; 005-768-932-409-528; 006-276-693-247-730; 006-685-064-013-541; 007-052-311-303-797; 007-877-466-638-635; 008-125-317-399-663; 010-090-234-585-035; 010-626-104-030-886; 011-027-520-016-276; 011-504-404-552-855; 012-323-967-052-938; 012-385-694-540-576; 012-742-087-808-043; 013-214-188-711-264; 013-343-117-625-482; 013-507-404-965-47X; 014-298-514-379-197; 017-716-204-062-432; 018-891-299-194-570; 019-263-272-045-144; 020-514-274-764-66X; 020-598-191-305-645; 022-755-099-259-075; 024-987-580-419-392; 025-183-661-487-162; 026-535-582-991-881; 027-197-388-305-187; 027-222-631-712-228; 028-183-270-463-533; 029-255-458-732-922; 029-805-738-143-894; 030-837-465-755-044; 032-227-506-197-523; 035-333-646-908-137; 036-065-537-784-030; 036-344-566-208-683; 036-972-041-163-58X; 039-402-124-914-945; 039-402-818-921-082; 039-797-797-169-221; 042-448-788-053-879; 043-477-708-340-309; 043-879-137-103-941; 044-634-761-562-27X; 047-042-189-069-862; 047-832-436-882-647; 049-046-072-384-034; 049-326-841-878-79X; 050-497-590-400-944; 052-082-831-633-799; 052-711-432-598-075; 054-161-931-029-351; 057-674-578-051-699; 059-310-890-978-646; 064-283-913-810-02X; 068-130-941-250-38X; 070-216-547-123-525; 073-114-875-010-230; 073-741-451-838-176; 074-333-366-978-549; 075-510-903-365-176; 075-869-799-118-861; 076-410-425-008-083; 077-623-796-022-728; 083-685-464-778-677; 088-110-673-987-090; 088-132-197-170-211; 090-857-741-630-665; 093-517-793-851-126; 094-952-042-898-225; 096-059-691-082-104; 096-464-941-949-436; 097-805-268-986-411; 098-117-329-096-162; 099-039-467-723-609; 102-746-243-264-174; 103-733-453-949-431; 105-544-445-384-944; 117-623-202-220-356; 118-487-896-399-727; 121-885-391-731-474; 124-169-532-071-054; 127-282-273-697-995; 128-706-676-645-420; 129-978-670-266-433; 132-742-854-495-182; 135-942-195-713-451; 143-379-985-460-807; 162-980-792-270-528; 171-533-164-627-487; 175-798-448-972-900; 179-055-571-152-623; 183-056-382-274-583; 194-802-079-030-173; 197-088-203-731-211,33,true,"CC BY, CC BY-NC, CC BY-NC-ND",gold -109-557-352-777-130,Recent research landscape on chitosan-mineral-based composites for wastewater treatment: a comprehensive bibliometric analysis (2014-2024).,2025-04-16,2025,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Fatiha Tafraout; Jalal Isaad,,32,19,11815,11837,Chitosan; Ecotoxicology; Wastewater; Environmental science; Materials science; Chemistry; Environmental engineering; Engineering; Environmental chemistry; Chemical engineering,Bibliometric analysis; Bibliometrix (R package); Chitosan; Composites; HistCite; Mineral; VOSviewer; Wastewater,"Chitosan/chemistry; Wastewater; Bibliometrics; Minerals; Waste Disposal, Fluid/methods; Adsorption; Water Pollutants, Chemical; Water Purification","Chitosan; Wastewater; Minerals; Water Pollutants, Chemical",,,http://dx.doi.org/10.1007/s11356-025-36387-3,40234321,10.1007/s11356-025-36387-3,,,0,000-324-390-997-046; 001-350-026-737-577; 002-052-422-936-00X; 005-395-941-160-577; 005-983-774-799-365; 008-851-433-459-850; 011-775-157-588-299; 012-480-687-044-65X; 012-839-907-371-280; 013-507-404-965-47X; 014-439-267-764-640; 015-281-832-197-079; 015-885-887-324-896; 017-958-809-551-142; 018-880-861-381-741; 020-422-959-085-389; 021-330-699-149-806; 021-713-415-873-412; 022-826-210-551-222; 025-214-649-678-627; 025-392-278-580-234; 027-291-499-389-361; 028-862-160-394-914; 029-241-135-853-626; 033-751-156-240-751; 034-070-407-920-51X; 037-978-405-232-392; 042-074-818-449-476; 043-444-182-512-119; 050-366-334-990-64X; 055-143-595-001-188; 055-792-897-662-512; 056-275-462-958-921; 058-525-937-176-459; 059-780-923-723-057; 060-530-280-627-769; 060-722-569-238-20X; 066-144-106-148-829; 069-213-938-088-369; 074-075-150-207-72X; 075-681-833-195-429; 080-138-198-787-711; 081-640-459-549-333; 084-773-285-321-15X; 086-310-154-830-167; 087-461-443-994-998; 087-558-295-899-032; 089-431-030-799-428; 091-175-715-409-826; 091-834-338-574-784; 093-077-769-036-870; 095-258-654-450-233; 095-826-135-047-576; 096-186-545-916-053; 101-754-065-755-280; 109-372-822-674-873; 114-931-774-544-087; 116-726-186-756-577; 116-935-692-041-049; 118-013-348-373-708; 121-795-964-426-25X; 128-773-980-089-270; 134-758-951-199-392; 134-848-588-483-151; 138-637-818-188-277; 140-907-298-372-634; 143-958-881-590-777; 145-343-787-393-664; 152-691-059-951-95X; 152-777-077-373-679; 161-568-590-846-604; 164-402-542-056-949; 169-009-539-739-74X; 175-528-911-626-314; 176-725-080-608-412; 178-767-044-065-48X; 178-948-951-194-35X; 179-514-557-799-041; 183-849-714-110-244; 191-978-605-210-298; 191-989-198-165-533; 192-874-820-541-743; 197-672-025-328-659,0,false,, -109-874-923-650-66X,Worldwide productivity and research trend of publications concerning tumor immune microenvironment (TIME): a bibliometric study.,2023-07-10,2023,journal article,European journal of medical research,2047783x; 09492321,Springer Science and Business Media LLC,Germany,Yao-Ge Liu; Shi-Tao Jiang; Lei Zhang; Han Zheng; Ting Zhang; Jun-Wei Zhang; Hai-Tao Zhao; Xin-Ting Sang; Yi-Yao Xu; Xin Lu,"As the complexity and diversity of the tumor immune microenvironment (TIME) are becoming better understood, burgeoning research has progressed in this field. However, there is a scarcity of literature specifically focused on the bibliometric analysis of this topic. This study sought to investigate the development pattern of TIME-related research from 2006 to September 14, 2022, from a bibliometric perspective.; We acquired both articles and reviews related to TIME from the Web of Science Core Collection (WoSCC) (retrieved on September 14, 2022). R package ""Bibliometrix"" was used to calculate the basic bibliometric features, present the collaborative conditions of countries and authors, and generate a three-field plot to show the relationships among authors, affiliations, and keywords. VOSviewer was utilized for co-authorship analysis of country and institution and keyword co-occurrence analysis. CiteSpace was used for citation burst analysis of keywords and cited references. In addition, Microsoft Office Excel 2019 was used to develop an exponential model to fit the cumulative publication numbers.; A total of 2545 publications on TIME were included, and the annual publication trend exhibited a significant increase over time. China and Fudan University were the most productive country and institution, with the highest number of publications of 1495 and 396, respectively. Frontiers in Oncology held the highest number of publications. A number of authors were recognized as the main contributors in this field. The clustering analysis revealed six clusters of keywords that highlighted the research hot spots in the fields of basic medical research, immunotherapy, and various cancer types separately.; This research analyzed 16 years of TIME-related research and sketched out a basic knowledge framework that includes publications, countries, journals, authors, institutions, and keywords. The finding revealed that the current research hot spots of the TIME domain lie in ""TIME and cancer prognosis"", ""cancer immunotherapy"", and ""immune checkpoint"". Our researchers identified the following areas: ""immune checkpoint-based immunotherapy"", ""precise immunotherapy"" and ""immunocyte pattern"", which may emerge as frontiers and focal points in the upcoming years, offering valuable avenues for further exploration.; © 2023. The Author(s).",28,1,229,,Bibliometrics; Citation; Citation analysis; Library science; Web of science; Productivity; Data science; Computer science; MEDLINE; Political science; Law; Economics; Macroeconomics,Bibliometrics; Citespace; Frontiers; Tumor immune microenvironment (TIME); VOSviewer,Humans; Bibliometrics; Biomedical Research; China; Dermatitis; Immunotherapy,,Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (CIFMS) (2020-I2M-CT-B-026); National High Level Hospital Clinical Research Funding (2022-PUMCH-C-049),https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-023-01195-3 https://doi.org/10.1186/s40001-023-01195-3 https://www.researchsquare.com/article/rs-2708181/latest.pdf https://doi.org/10.21203/rs.3.rs-2708181/v1,http://dx.doi.org/10.1186/s40001-023-01195-3,37430294,10.1186/s40001-023-01195-3,,PMC10332017,0,000-206-881-867-310; 001-510-218-248-33X; 001-780-362-352-713; 002-052-422-936-00X; 004-159-783-828-138; 005-962-986-743-408; 006-568-097-103-41X; 007-024-180-386-992; 007-707-507-302-416; 008-409-927-536-172; 008-538-322-355-038; 009-298-144-435-84X; 010-194-028-604-828; 011-301-822-302-672; 012-070-853-524-500; 012-618-728-902-171; 013-502-367-090-164; 014-924-628-253-475; 014-954-239-970-216; 014-966-742-559-190; 015-627-072-996-286; 016-924-877-152-627; 019-142-871-202-067; 021-859-833-451-468; 022-060-065-062-10X; 022-417-211-569-320; 022-470-987-962-325; 023-360-738-858-702; 024-273-259-060-50X; 024-745-743-866-129; 025-047-339-835-003; 025-073-392-854-608; 025-271-015-458-754; 025-376-630-698-822; 025-582-189-305-06X; 026-001-768-185-582; 026-698-789-428-742; 027-690-220-065-414; 029-580-574-393-197; 033-159-791-900-680; 033-749-564-559-523; 034-431-257-436-693; 034-918-096-765-537; 037-417-829-246-800; 038-040-632-602-487; 038-289-464-864-35X; 039-998-002-133-876; 040-448-840-183-222; 040-887-679-477-746; 042-568-201-870-973; 045-623-729-340-346; 047-396-163-897-529; 048-060-748-635-820; 048-329-582-726-050; 053-094-104-678-864; 053-367-920-129-127; 054-119-704-214-048; 054-786-488-292-293; 059-715-448-782-195; 060-199-818-406-662; 061-715-158-220-540; 064-400-499-357-900; 067-533-390-014-814; 067-999-346-813-277; 068-353-029-028-199; 069-941-665-698-430; 071-748-625-396-785; 071-892-386-859-768; 075-377-399-568-133; 076-953-605-768-654; 082-250-308-281-846; 082-939-898-616-246; 083-406-801-050-19X; 084-706-022-991-610; 086-082-420-041-08X; 086-270-345-518-99X; 088-285-654-060-825; 089-275-077-807-50X; 089-822-526-631-598; 100-444-159-623-481; 101-298-707-872-678; 104-025-983-721-222; 104-236-149-773-098; 104-967-719-941-030; 106-422-533-603-095; 107-491-486-094-691; 117-168-940-761-806; 119-950-069-548-512; 124-586-890-817-124; 148-004-098-947-855,9,true,"CC BY, CC0",gold -109-899-125-222-426,Destination Image and Trust in Tourism: A Comprehensive Bibliometric Exploration using R-Tool Bibliometrix,2024-06-13,2024,journal article,"Journal of Logistics, Informatics and Service Science",24092665,Hong Kong Success Culture Press,,Iwan Suparman; Bambang Sukoco; Rivani Hermanto,"Understanding the relationship between destination image and destination trust is crucial for sustainable tourism development.This bibliometric study aims to analyze the research trends and future directions in this field by examining 330 publications from the Scopus database between 2006 and 2023.Utilizing the R-Tool Bibliometrix, the authors conduct performance analysis and science mapping techniques to identify significant sources, authors, countries, affiliations, and influential articles.The findings reveal a steady but declining growth in citations related to destination image and trust, highlighting the need for further research.Thematic maps and trend analysis indicate an emphasis on emotional responses and the influence of social media, particularly among younger generations, in shaping destination choices.The study suggests expanding the destination image literature to incorporate emotional factors and leveraging social media insights to foster authentic tourist experiences.By providing a comprehensive bibliometric analysis, this research offers valuable insights for tourism researchers, practitioners, and policymakers to strategically manage destination image and build trust among visitors.",,,,,Tourism; Destination image; Image (mathematics); Regional science; Computer science; Data science; Geography; Artificial intelligence; Destinations; Archaeology,,,,,,http://dx.doi.org/10.33168/jliss.2024.0825,,10.33168/jliss.2024.0825,,,0,,0,true,,gold -109-988-339-359-203,НАУКОВЕ КАРТОГРАФУВАННЯ ДОСЛІДНИЦЬКОГО ПОЛЯ КОНКУРЕНТНИХ ПЕРЕВАГ РОЗВИТКУ ТЕРИТОРІЙ ЗА ДОПОМОГОЮ BIBLIOMETRIX R-PACKAGE,2023-11-28,2023,journal article,Економіка та суспільство,25240072,Publishing House Helvetica (Publications),,Володимир Родченко; Лю Дзеюй,"У статті проведено дослідження наукової літератури, що стосується проблематики конкурентного розвитку територій. Основним інформаційним джерелом дослідження виступила наукометрична база даних Scopus, найбільша бази даних рецензованої літератури, за ключовими словами «конкурентна перевага», «територія», «регіон». Вибірка наукової літератури склала 566 документів. Період дослідження опублікованих документів з 1990 по 2023 роки. Були встановлені країни, що мають найбільшу кількість публікацій в розрізі конкретних університетів, а також найбільш цитовані публікації за вказаним напрямом. За результатами аналізу наукової літератури було встановлено, що існує чітка залежність між розвиток територій та його конкурентоспроможністю, оскільки забезпечення конкурентоспроможності є однією з основних цілей цього процесу.",,57,,,Scopus; Political science; MEDLINE; Law,,,,,https://economyandsociety.in.ua/index.php/journal/article/download/3201/3124 https://doi.org/10.32782/2524-0072/2023-57-91,http://dx.doi.org/10.32782/2524-0072/2023-57-91,,10.32782/2524-0072/2023-57-91,,,0,004-713-136-808-304; 008-009-604-491-835; 013-507-404-965-47X; 017-750-600-412-958; 027-649-326-747-267; 030-284-927-888-240; 046-693-316-405-99X; 054-386-268-698-416; 058-686-353-645-378; 065-433-028-960-348; 071-313-229-517-036; 073-810-964-358-940; 102-323-318-847-151; 114-306-424-542-379; 155-228-587-335-717; 174-350-268-130-296; 186-255-846-265-978; 190-975-337-312-094,0,true,cc-by,gold -110-245-177-315-125,The big picture on supply chain integration – insights from a bibliometric analysis,2021-08-26,2021,journal article,Supply Chain Management: An International Journal,13598546,Emerald,United Kingdom,Herbert Kotzab; Ilja Bäumler; Paul Gerken,"; Purpose; Integration is a key element of supply chain management (SCM) and a lot of research has been executed within the field of supply chain integration (SCI). The purpose of this paper is to particularly identify the intellectual research front and foundation of SCI and how they developed over time.; ; ; Design/methodology/approach; The authors examined more than 1,700 peer-reviewed academic papers that were published between 1995 and 2019 in nearly 40 relevant peer-reviewed academic journals (all indexed in Web of Science). The authors analysed the structure of more than 55,000 individual references with the R-package bibliometrix and used VOSviewer for visualization.; ; ; Findings; The SCI research front is characterized by papers that show the effects of SCI on the firm performance, the consequences of SCI on SCM in general and present the enablers of SCI. The research front is embedded within the resource-based, transaction cost and contingency theory. The intellectual foundation refers to conceptual modelling, definitional clarification and integration dimensions. The research identifies Frohlich and Westbrook’s (2001) paper as the central reference for this research area. The dynamic evolution of the intellectual foundation of SCI changed from theorising in Phase 1 (1995–2006) towards empirical testing in Phase 2 (2007–2019).; ; ; Research limitations/implications; The results refer to the SCI discussion within a preselected number of peer-reviewed academic journals and to the data quality as provided by the Web of Science.; ; ; Originality/value; The study explored the research front and intellectual foundation of SCI. It reveals the most important papers and journals of this area by using bibliometric tools such as bibliometrix, biblioshiny and VOSviewer. The paper shows trends in research themes, theories and methodological developments.; ",28,1,25,54,Citation analysis; Business; Supply chain integration; Bibliometric analysis; Industrial organization; Supply chain management,,,,,https://www.emerald.com/insight/content/doi/10.1108/SCM-09-2020-0496/full/html,http://dx.doi.org/10.1108/scm-09-2020-0496,,10.1108/scm-09-2020-0496,3195014775,,0,000-742-487-988-420; 001-258-379-110-671; 001-262-274-011-134; 002-052-422-936-00X; 002-824-794-276-88X; 003-053-686-306-07X; 003-162-325-451-522; 004-416-052-037-484; 004-771-103-585-250; 005-178-616-037-806; 005-447-642-522-39X; 005-805-453-463-041; 006-279-802-942-331; 006-392-065-250-62X; 007-506-383-748-350; 007-669-540-910-566; 008-731-149-094-974; 008-911-146-716-860; 008-945-143-527-621; 009-578-814-099-90X; 010-005-886-670-172; 010-854-534-444-434; 011-055-938-068-901; 011-133-641-435-345; 011-489-835-244-35X; 013-507-404-965-47X; 014-407-819-667-739; 015-320-715-465-07X; 015-774-079-830-633; 016-140-802-569-916; 017-750-600-412-958; 018-112-012-236-898; 019-352-274-873-861; 019-785-607-877-590; 022-509-785-910-67X; 022-691-516-276-125; 022-774-738-500-720; 023-194-888-807-993; 023-487-642-285-020; 023-790-190-496-186; 025-536-109-121-643; 027-883-953-233-869; 027-981-338-751-233; 028-257-724-303-489; 029-436-055-511-212; 030-091-806-693-403; 030-484-520-117-213; 030-671-248-846-321; 031-137-863-724-39X; 032-108-277-083-837; 033-098-710-108-813; 033-171-354-077-456; 034-145-218-792-807; 035-939-328-217-88X; 036-254-229-200-972; 037-931-247-332-487; 039-558-436-414-473; 039-604-017-131-713; 039-919-367-251-316; 040-054-429-278-481; 040-763-632-606-42X; 042-028-762-478-755; 042-400-229-654-018; 042-651-238-283-868; 042-911-354-037-478; 042-946-578-008-692; 042-970-223-978-163; 043-169-872-205-972; 043-382-069-845-359; 044-631-253-138-495; 047-134-478-431-993; 047-382-020-893-945; 047-621-775-532-22X; 047-651-570-387-847; 048-822-371-006-95X; 049-192-461-558-267; 049-682-867-290-960; 049-769-542-670-772; 052-539-552-705-689; 052-934-250-349-148; 053-306-703-077-106; 053-444-352-054-484; 053-876-046-265-645; 055-004-340-741-491; 056-113-755-580-22X; 056-696-770-556-92X; 059-669-059-794-833; 061-848-408-784-816; 065-894-544-103-571; 066-151-726-987-215; 066-851-347-137-031; 068-153-836-991-209; 068-803-540-852-279; 068-967-380-033-83X; 070-603-005-724-334; 071-185-310-932-372; 071-645-334-936-305; 072-217-053-472-108; 072-748-060-664-629; 073-494-210-161-306; 074-389-312-849-197; 075-117-658-850-934; 076-330-095-102-076; 078-077-895-276-695; 078-742-152-129-667; 079-278-714-415-834; 080-958-300-925-863; 080-976-318-089-970; 085-359-862-772-990; 085-633-505-540-867; 086-341-446-522-651; 086-572-669-958-653; 088-451-941-256-274; 089-621-912-811-772; 092-141-640-185-100; 092-286-415-402-68X; 094-677-960-011-984; 094-921-205-597-813; 094-975-570-706-559; 096-652-207-701-290; 098-140-974-143-887; 098-565-104-723-427; 099-368-892-154-539; 100-294-259-882-658; 101-895-837-634-155; 102-038-640-751-200; 102-059-131-930-537; 102-498-335-759-625; 103-705-771-764-928; 105-538-482-028-753; 107-191-743-907-952; 108-047-155-050-251; 108-258-628-873-275; 111-649-410-597-761; 113-097-696-617-229; 113-857-886-875-869; 114-972-782-390-437; 116-953-447-460-185; 117-378-811-588-897; 120-974-286-046-262; 122-107-855-481-641; 123-221-946-494-187; 129-093-638-266-398; 130-167-885-005-050; 132-370-255-349-269; 133-538-932-930-118; 138-122-594-956-683; 142-059-731-334-668; 142-577-692-109-993; 149-237-986-021-528; 151-198-972-962-725; 153-084-205-956-516; 157-346-370-700-605; 164-071-904-286-343; 165-821-001-929-99X; 166-823-716-452-65X; 179-561-342-091-478; 179-608-372-698-452; 194-038-467-320-673,22,false,, -110-553-200-395-712,Effect of COVID-19 on agricultural production and food security: A scientometric analysis,2022-02-28,2022,journal article,Humanities and Social Sciences Communications,26629992,Springer Science and Business Media LLC,,Collins C. Okolie; Abiodun A. Ogundeji,"AbstractCoronavirus disease has created an unexpected negative situation globally, impacting the agricultural sector, economy, human health, and food security. This study examined research on COVID-19 in relation to agricultural production and food security. Research articles published in Web of Science and Scopus were sourced, considering critical situations and circumstance posed by COVID-19 pandemic with regards to the shortage of agricultural production activities and threat to food security systems. In total, 174 published papers in BibTeX format were downloaded for further study. To assess the relevant documents, authors used “effects of COVID-19 on agricultural production and food security (ECAP-FS) as a search keyword for research published between 2016 and April 2021 utilising bibliometric innovative methods. The findings indicated an annual growth rate of about 56.64%, indicating that research on ECAP-FS increased over time within the study period. Nevertheless, the research output on ECAP-FS varied with 2020 accounting for 38.5%, followed by 2021 with 37.9% as at April 2021. The proposed four stage processes for merging two databases for bibliometric analyses clearly showed that one can run collaboration network analyses, authors coupling among other analyses by following our procedure and finally using net2VOSviewer, which is embedded in Rstudio software package. The study concluded that interruptions in agricultural food supply as a result of the pandemic impacted supply and demand shocks with negative impacts on all the four pillars of food security.",9,1,,,Food security; Agriculture; Scopus; Agricultural productivity; Agricultural economics; Production (economics); Coronavirus disease 2019 (COVID-19); Pandemic; Food processing; Business; Web of science; Food supply; Economic shortage; Good agricultural practice; Agricultural science; Natural resource economics; Economics; Geography; Political science; Food systems; Environmental science; Disease; Medicine; Infectious disease (medical specialty); MEDLINE; Law; Macroeconomics; Archaeology; Pathology; Philosophy; Government (linguistics); Linguistics,,,,,https://www.nature.com/articles/s41599-022-01080-0.pdf https://doi.org/10.1057/s41599-022-01080-0,http://dx.doi.org/10.1057/s41599-022-01080-0,,10.1057/s41599-022-01080-0,,,0,007-251-447-518-182; 007-530-002-185-583; 009-416-495-191-220; 011-301-822-302-672; 012-868-126-283-512; 013-507-404-965-47X; 015-496-953-880-542; 019-565-928-239-413; 020-803-334-129-248; 021-381-087-145-097; 022-050-154-142-786; 023-786-075-290-068; 024-723-514-611-328; 028-058-478-307-107; 029-260-840-422-833; 029-762-777-759-678; 035-330-847-069-591; 045-692-294-832-841; 056-751-662-129-25X; 062-219-725-968-461; 067-312-604-323-809; 073-008-010-322-076; 073-677-424-961-095; 083-643-200-062-290; 085-300-287-100-525; 085-613-443-797-588; 087-999-140-003-717; 092-473-686-873-153; 092-578-397-280-221; 097-759-447-260-523; 097-778-903-506-712; 097-862-784-304-342; 098-375-514-007-485; 105-463-486-281-293; 108-860-199-271-111; 110-857-719-991-409; 111-032-138-733-516; 128-605-691-832-803; 132-032-740-059-861; 136-390-995-943-435; 141-289-222-959-472; 163-928-270-078-035,58,true,cc-by,gold -110-553-732-175-956,Research Hotspots and Frontiers of Alzheimer's Disease and Gut Microbiota: A Knowledge Mapping and Text Mining Analysis.,2024-04-18,2024,journal article,Molecular neurobiology,15591182; 08937648,Springer Science and Business Media LLC,United States,Youao Zhang; Zixuan Jia; Jieyan Wang; Hui Liang,,61,11,9369,9382,Gut flora; Disease; Data science; Web of science; Biology; Bioinformatics; Medicine; MEDLINE; Computer science; Immunology; Pathology; Biochemistry,Alzheimer’s disease; Bibliometric; Frontiers; Gut microbiota; Hotspots; Visual analysis,Humans; Alzheimer Disease/microbiology; Bibliometrics; Data Mining/methods; Gastrointestinal Microbiome/physiology,,"Special Fund Project for Science and Technology Innovation Strategy of Guangdong Province (pdjh2023b0107); National College Students Innovation and Entrepreneurship Training Program (202212121008); Scientific Research Projects of Medical and Health Institutions of Longhua District, Shenzhen (2021017); Project of Guangdong Medical Science and Technology Research Fund (A2022362); Shenzhen Fundamental Research Program (JCYJ20220530165014033); Medical Key Discipline of Longhua, Shenzhen (MKD202007090201)",,http://dx.doi.org/10.1007/s12035-024-04168-7,38632152,10.1007/s12035-024-04168-7,,,0,000-765-138-880-27X; 001-982-788-348-709; 003-034-665-176-76X; 005-079-387-850-815; 008-626-120-907-818; 008-633-657-886-522; 009-439-245-970-178; 009-864-930-949-286; 012-354-547-537-041; 013-507-404-965-47X; 013-516-159-854-788; 014-457-234-552-165; 014-680-286-176-116; 015-523-483-981-365; 017-398-200-782-917; 024-813-305-271-039; 024-837-049-066-445; 026-336-758-636-727; 026-395-112-558-483; 028-083-374-564-031; 029-931-015-316-170; 031-260-181-705-064; 031-426-130-973-269; 032-227-242-966-498; 032-347-382-015-391; 033-122-711-162-966; 035-609-673-773-535; 038-477-982-061-897; 041-727-713-632-193; 042-592-538-287-345; 043-120-711-657-188; 044-455-261-735-492; 046-392-307-093-032; 055-448-052-329-985; 056-303-988-895-588; 059-532-758-728-694; 065-472-670-467-165; 074-876-821-838-400; 075-798-384-084-676; 075-847-136-660-812; 078-944-828-490-707; 089-860-525-802-639; 090-772-164-500-103; 090-773-103-073-755; 094-990-471-382-929; 095-353-383-178-340; 096-000-659-946-199; 099-067-393-641-886; 123-870-539-062-870; 132-506-022-667-960; 181-387-685-690-641,6,false,, -110-782-331-630-355,Analysis of Reports on the Occupational Health and Safety in The Agricultural Industry: A bibliometrix-Aided Approach,2023-12-01,2023,journal article,Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi,25364618,Igdir University,,Okan ÖZBAKIR,"Agricultural activities are fundamental to societies, including the planting, growing, harvesting and processing of agricultural crops. However, there are a large number of occupational risks that can arise during the course of agricultural activities. These risks could result in serious injury or even death. This requires introducing and providing the relevant bodies and workers with knowledge, perception and awareness of the risk. The present study assessed the available reports on occupational health and safety using a bibliometric analysis and dimension reduction approach. Briefly, the reports were extracted from SCOPUS database. We identified 943 relevant and available peer-reviewed publications from the Scopus database. These were published between 1956 and 2022. The retrieved documents were analysed with the R-studio based software Bibliometrix. For the analysis, co-occurrences of networks, thematic maps and trending topics were analyzed. The results of the present study show that the time span of the documents ranges from 1956 to 2022 and these documents, including journals, books, book chapters and conference papers, were disseminated in 313 different sources. The estimated annual growth rate of these documents is 6.35%. Even the first paper dates back to the 1950s, the average age of the documents are 10.7. Considering the spatial distribution of the documents, USA topped at the list and was followed by Australia, Brazil, Italy, Canada, UK, and China. It is interesting to note that 'confined spaces' were found to be the trending topic according to the trend topic analysis of the keywords. Also, after the basic keywords (occupational health and safety and agriculture) of the study, ergonomics was the core keyword of the relevant analysis. Critically, the level of co-operation between countries was very low, with a rate of 0.025-0.207 for co-operation between countries (MCPs). For Turkey, the MCP was found to be 0.000. According to the thematic map, the motor theme is composed of two major clusters. One relates to food safety, risk analysis, knowledge and awareness and hygiene. To the best of our knowledge, this is the first study of its kind to identify the key issues in occupational health and safety in the agricultural industry. Therefore, the study has potential to contribute to the field.",13,4,2516,2531,Scopus; Agriculture; Thematic map; Thematic analysis; China; Occupational injury; Occupational safety and health; Geography; Business; Environmental health; Medicine; Political science; MEDLINE; Social science; Cartography; Sociology; Human factors and ergonomics; Poison control; Qualitative research; Archaeology; Pathology; Law,,,,,https://dergipark.org.tr/en/download/article-file/3176948 https://doi.org/10.21597/jist.1307071,http://dx.doi.org/10.21597/jist.1307071,,10.21597/jist.1307071,,,0,003-310-656-958-813; 008-417-185-917-514; 011-294-360-691-323; 015-674-178-675-327; 018-192-895-953-278; 037-271-946-148-32X; 039-702-588-205-658; 044-501-968-205-211; 045-890-845-577-881; 050-712-785-510-755; 054-497-326-384-928; 055-605-216-867-015; 067-106-329-865-349; 068-665-117-716-437; 072-324-090-726-887; 074-001-832-170-811; 076-802-642-714-745; 099-948-692-015-906; 122-415-544-444-960; 125-247-662-244-184; 151-368-328-176-546; 162-240-807-285-033; 169-122-440-973-311; 174-752-658-017-848; 179-690-311-575-673,1,true,,bronze -111-174-739-114-917,Big data optimisation and management in supply chain management: a systematic literature review,2023-06-24,2023,journal article,Artificial Intelligence Review,02692821; 15737462,Springer Science and Business Media LLC,Netherlands,Idrees Alsolbi; Fahimeh Hosseinnia Shavaki; Renu Agarwal; Gnana K Bharathy; Shiv Prakash; Mukesh Prasad,"AbstractThe increasing interest from technology enthusiasts and organisational practitioners in big data applications in the supply chain has encouraged us to review recent research development. This paper proposes a systematic literature review to explore the available peer-reviewed literature on how big data is widely optimised and managed within the supply chain management context. Although big data applications in supply chain management appear to be often studied and reported in the literature, different angles of big data optimisation and management technologies in the supply chain are not clearly identified. This paper adopts the explanatory literature review involving bibliometric analysis as the primary research method to answer two research questions, namely: (1) How to optimise big data in supply chain management? and (2) What tools are most used to manage big data in supply chain management? A total of thirty-seven related papers are reviewed to answer the two research questions using the content analysis method. The paper also reveals some research gaps that lead to prospective future research directions.",56,S1,253,284,Big data; Supply chain management; Supply chain; Systematic review; Context (archaeology); Computer science; Data science; Data management; Knowledge management; Management science; Process management; Business; Marketing; Data mining; MEDLINE; Engineering; Political science; Paleontology; Law; Biology,,,,University of Technology Sydney,https://link.springer.com/content/pdf/10.1007/s10462-023-10505-4.pdf https://doi.org/10.1007/s10462-023-10505-4,http://dx.doi.org/10.1007/s10462-023-10505-4,,10.1007/s10462-023-10505-4,,,0,001-376-641-790-869; 002-980-933-636-254; 004-676-180-052-575; 004-977-823-090-25X; 006-279-802-942-331; 006-912-721-410-174; 007-243-311-179-011; 008-995-700-430-108; 011-871-848-229-551; 013-507-404-965-47X; 016-109-369-993-314; 017-241-410-696-595; 017-908-257-685-912; 018-831-164-347-336; 019-211-242-591-983; 019-549-789-168-810; 019-948-637-330-207; 020-162-294-505-351; 022-313-028-352-805; 023-194-408-002-476; 023-964-864-644-120; 024-759-822-262-523; 031-949-754-297-134; 032-851-984-840-826; 036-094-394-326-923; 038-965-642-922-85X; 040-517-085-915-464; 045-627-000-745-988; 046-066-181-781-53X; 046-992-864-415-70X; 048-573-510-616-770; 050-118-441-654-470; 054-266-200-187-509; 054-695-406-194-355; 055-497-223-459-671; 055-678-008-791-092; 057-632-703-338-475; 058-019-776-311-75X; 058-264-021-351-517; 058-845-936-786-215; 062-071-314-205-971; 063-372-323-600-936; 066-561-149-680-337; 066-945-659-705-381; 071-031-078-119-720; 073-225-952-232-286; 073-331-021-736-469; 076-234-591-142-835; 077-873-731-285-967; 081-025-834-219-56X; 083-575-974-747-777; 084-262-644-028-883; 086-265-049-859-785; 088-531-564-882-068; 091-468-545-338-541; 091-779-969-090-12X; 092-273-559-827-721; 095-173-321-863-379; 097-013-076-293-367; 100-995-094-701-629; 105-757-158-726-998; 106-819-939-605-934; 112-405-138-751-20X; 112-740-496-382-393; 113-003-851-759-690; 123-075-792-876-314; 133-580-030-707-901; 134-376-055-779-643; 137-292-579-653-532; 137-872-994-309-043; 142-975-107-949-320; 143-893-240-591-767; 148-896-136-765-806; 148-955-889-098-099; 149-879-244-312-11X; 158-667-002-526-141; 161-156-386-041-285; 170-615-170-682-362; 171-107-130-663-04X; 172-257-189-323-533,10,true,cc-by,hybrid -111-185-564-985-705,"Research Landscape, Emerging Trends and New Developments in Data Warehouse: A Scientometric Analysis (1985 - 2021)",,2022,conference proceedings article,Proceedings of 2022 the 12th International Workshop on Computer Science and Engineering,,WCSE,,Changjun Fan; Li Zeng; Kuihua Huang,"As the core component of bussiness intelligence, Data Warehouse (DW) has been studied by academia and industry for many years.In this paper, a scientometric review of DW over the past 30 years was conducted, with the aim to capture the landscapes, research hotspots and emerging trends in this field.The dataset was gathered from Web of Science between 1985 to 2021.Besides basic scientific outputs assessment based on statistical analysis and comparative analysis, scientometric softwares such as Citespace, VOSViewer and Bibliometrix were used to analysis the knowldege structure of Data Warehouse.Results showed that Data Warehouse research went up significantly in the past two decades, including a total of 2529 articles covering 93 countries/territories, and the top five most productive countries are USA, China, France, India, Germany, and Spain.There are 2028 research institutes involved in the field of DW and the top five most influential institutes are",,,,,Data warehouse; Data science; Computer science; Regional science; Geography; Database,,,,,,http://dx.doi.org/10.18178/wcse.2022.06.019,,10.18178/wcse.2022.06.019,,,0,,0,true,,bronze -111-197-606-516-658,Bibliometric study on information overload in online teaching,2024-12-15,2024,book chapter,Transformación digital en la educación: innovaciones y desafíos,,United Academic Journals (UA Journals),,Alfonso Infante-Moro; Juan C. Infante-Moro; Julia Gallardo-Pérez; Álvaro Martínez-García; Rocío B. Borrero-Ojuelos; Catalina Guerrero-Romera,"This article makes a bibliometric study on information overload in subjects or material overload in online teaching. A bibliometric study of the articles that are indexed in Scopus with the Bibliometrix tool, which shows a research area that is receiving more publications every year, where these articles are being published and who are the authors, universities and countries that are delving into this topic.",,,121,125,Information overload; Computer science; Psychology; Mathematics education; World Wide Web,,,,,,http://dx.doi.org/10.54988/uaj.000029.019,,10.54988/uaj.000029.019,,,0,,0,false,, -111-235-425-503-449,"A Bibliometric Analysis on ""E-Assessment in Teaching English as a Foreign Language"" Publications in Web of Science (WoS)",2023-01-13,2023,book chapter,Advances in Educational Technologies and Instructional Design,23268905; 23268913,IGI Global,,Devrim Höl; Ezgi Akman,"This chapter aimed to examine the e-assessment in second/foreign language teaching-themed international publications from WoS (Web of Science) using the bibliometric method, one of the literature review tools. In particular, the most prolific countries, annual scientific production, the most globally cited documents, authors, institutions, keywords, and changing research trends were analyzed. A total of 3352 research documents from the Web of Science (WoS) Core Collection database were included in the analysis including publications until June 2022. In the analysis of the data obtained, the open-source R Studio program and the “biblioshiny for bibliometrix” application, which is an R program tool, were used. Based on the data analysis and discussions of these documents, this study has revealed some important results that will contribute to the field of trends of e-assessment in second/foreign language teaching.",,,329,355,Web of science; Foreign language; Computer science; Field (mathematics); Library science; Studio; Citation analysis; World Wide Web; Data science; Political science; Citation; Mathematics education; Psychology; MEDLINE; Mathematics; Telecommunications; Pure mathematics; Law,,,,,,http://dx.doi.org/10.4018/978-1-6684-5660-6.ch016,,10.4018/978-1-6684-5660-6.ch016,,,0,001-541-110-784-482; 003-291-383-867-279; 011-708-908-444-609; 012-524-731-126-954; 016-655-706-124-813; 016-957-389-838-807; 017-951-537-413-747; 020-104-312-328-091; 021-086-522-197-480; 022-459-174-591-451; 024-059-687-141-747; 024-582-982-572-984; 024-977-292-810-101; 026-948-566-285-755; 030-419-971-114-475; 031-261-846-523-068; 031-287-412-432-666; 031-352-440-686-362; 031-707-620-051-786; 034-768-039-318-254; 039-231-005-831-908; 041-782-088-173-279; 044-873-666-774-416; 045-821-008-465-509; 054-818-565-070-154; 055-190-877-961-592; 062-238-030-541-609; 066-460-210-845-856; 066-575-038-886-532; 067-749-833-408-39X; 075-022-031-259-305; 085-345-739-679-400; 089-366-348-638-191; 089-641-991-322-771; 104-660-380-562-077; 105-932-879-927-20X; 109-342-671-942-908; 120-194-225-902-11X; 127-886-841-823-468; 136-682-641-219-014; 144-295-057-224-498; 165-633-604-053-159,2,false,, -111-255-867-511-399,Bibliometric analysis and visualisation of research on life cycle assessment in Africa (1992–2022),2024-04-24,2024,journal article,The International Journal of Life Cycle Assessment,09483349; 16147502,Springer Science and Business Media LLC,Germany,Mohammed Engha Isah; Zhengyang Zhang; Kazuyo Matsubae; Norihiro Itsubo,"Abstract; Purpose; Life cycle assessment (LCA) has found wide applicability as a tool for assessing the environmental impacts of human activities in different fields such as manufacturing, mining, transportation, oil and gas, construction, and medicine. Despite the wide applicability of LCA globally, the uptake and use of the tool in Africa remains limited. This research is motivated by the need to explore the continental structure of life cycle assessment to ascertain the level of knowledge and research; collaboration amongst institutions, countries, and authors; keyword co-occurrence; thematic evolution; and bibliographic coupling.; ; Methods; Publications related to life cycle assessment were retrieved and cleaned from the Scopus database with the language restricted to English and only countries recognised by the African Union. VOSviewer (version 1.6.19) visualisation tool was used to construct and visualise the network maps of researchers, co-occurrence, co-authorships, and keywords. On the other hand, Bibliometrix was employed to carryout descriptive analysis and thematic evolution and to extract bibliographic information.; ; Results and discussion; In total, 616 research publications between 1992 and 2022 were retrieved. The results show that research on the subject matter picked up from 2004 and has been on the upward trend. South Africa, Egypt, Tunisia, and Algeria are the top countries carrying out LCA research on the continent. In addition, the top authors, affiliations, and funders also come from these countries. It was also noted that there were low levels of cooperation between authors on the African continent; rather, they collaborate more with researchers in Europe, America, and other parts of the world. The built environment, construction industry, alternative energy, agriculture, and waste management and recycling are the major themes of research on the continent.; ; Conclusion; Life cycle assessment is gaining traction amongst researchers in Africa, albeit slowly. Considering the continents’ role in the future especially in providing critical raw materials needed for the transition to a carbon-neutral society in line with the Sustainable Development Goals (SDGs), rapid uptake and embedding life cycle thinking in every sector of the African economy are needed. However, there is an urgent need to equip researchers with the skills to facilitate the development of a life cycle inventory (LCI) database at countries or continental level.; ",29,7,1339,1351,Scopus; Thematic analysis; Life-cycle assessment; Construct (python library); Thematic map; Geography; Regional science; Political science; Library science; Social science; Sociology; Computer science; Qualitative research; Cartography; MEDLINE; Economics; Macroeconomics; Production (economics); Law; Programming language,,,,JST-Mirai Program,,http://dx.doi.org/10.1007/s11367-024-02313-x,,10.1007/s11367-024-02313-x,,,0,000-568-403-472-742; 001-947-443-911-136; 005-770-096-246-606; 007-134-380-595-446; 009-286-240-384-618; 011-338-160-218-306; 013-507-404-965-47X; 017-733-294-850-823; 017-750-600-412-958; 021-410-510-232-332; 022-050-154-142-786; 030-422-426-801-795; 034-469-712-138-49X; 041-096-082-952-765; 043-382-069-845-359; 044-298-287-467-936; 046-189-903-978-87X; 047-166-273-054-238; 048-529-152-895-184; 049-122-998-039-658; 050-455-808-711-45X; 053-659-763-234-007; 054-440-356-297-182; 054-598-482-138-553; 060-005-575-278-599; 060-971-652-958-643; 061-031-239-304-984; 065-010-405-236-060; 065-946-388-198-856; 072-005-663-601-048; 074-768-828-277-53X; 078-000-956-283-560; 081-535-718-086-405; 083-311-225-108-952; 085-300-287-100-525; 089-637-657-577-419; 097-915-831-522-331; 104-812-084-836-424; 107-957-337-321-717; 141-200-607-894-303; 143-029-948-541-333; 157-888-776-047-606; 161-156-386-041-285; 176-373-175-887-892,8,true,cc-by,hybrid -111-358-040-689-019,"Comment on ""An overview of the 35 years of research in the oral radiology: a bibliometric analysis"".",2022-06-10,2022,letter,Oral radiology,16139674; 09116028,Springer Science and Business Media LLC,Japan,Waseem Hassan,,38,4,651,651,Medicine; Oral and maxillofacial surgery; Medical physics; Bibliometrics; Oral and maxillofacial radiology; Dentistry; Radiology; General surgery; Library science; Computer science,37 Years; Bibliometric analysis; Oral radiology,Bibliometrics; Radiography; Radiology,,,https://link.springer.com/content/pdf/10.1007/s11282-022-00632-z.pdf https://doi.org/10.1007/s11282-022-00632-z,http://dx.doi.org/10.1007/s11282-022-00632-z,35687280,10.1007/s11282-022-00632-z,,,0,012-270-834-628-634,1,true,,bronze -111-885-824-930-020,Quantitatively mapping the research status and trends of vegetation responses to climate change with bibliometric analysis,2023-07-13,2023,journal article,Journal of Soils and Sediments,14390108; 16147480,Springer Science and Business Media LLC,Germany,Xinzhe Li; Zhiqiang Wen; Lizhen Cui; Yang Chen; Tong Li; Hongdou Liu; Zhihong Xu; Xiaoyong Cui; Xiufang Song,"Abstract; Purpose; Vegetation is a typical sensitive indicator of climate change, and therefore provides theoretical and valuable information for addressing issues arising from climate change including improving soil ecosystem services. Exploring how vegetation responses to climate change has become one of major hotspots of research. However, few scholars have performed bibliometric analyses of this field. This study investigated the current research activities and the trend developments of vegetation responses to climate change.; ; Materials and methods; We conducted a quantitative bibliometric analysis of 2,310 publications on vegetation responses to climate change from 1991 to 2021 retrieved in the Web of Science Core Collection. The analysis comprised significant journals, disciplines, and scholars, as well as partnerships between countries and institutions, keyword co-occurrence and burst analysis. The bibliometric analysis tools, Histcite, Vosviewer, CiteSpace software, and R (Bibliometrix package), were applied.; ; Results and discussion; The related publications on vegetation responses to climate change had been increasing exponentially in the past 30 years and its total global cited score reached its peak in 2010. The USA and China were the leading countries, with the Chinese Academy of Sciences having the highest number of publications and citations. The scholars who had the most citations were Allen CD, Bresears DD, and Running SW. Six research clusters were generated by keywords co-occurrence analysis, including impact, response, CO2, growth, climate change, and vegetation. These clusters represented the current research topics that highlighted the responses of vegetation to climate change, the manifestation of its impact, and coping strategies. In future research on vegetation, the emphasis is expected to be placed on “human activities” and “N2O emission”.; ; Conclusion; This study has performed a comprehensive and systematic and quantitative analysis of the publications on the responses of vegetation to climate change. The results reveal the characteristics, development patterns, and research trends of studies on vegetation activity in response to climate change, which sheds new insights into understanding the relationship between soil and climate.; ",23,8,2963,2979,Climate change; Vegetation (pathology); Bibliometrics; Geography; Trend analysis; Environmental resource management; Physical geography; Change analysis; Environmental science; Library science; Ecology; Computer science; Medicine; Pathology; Machine learning; Biology,,,,the CAS Strategic Priority Research Program; Griffith University,https://link.springer.com/content/pdf/10.1007/s11368-023-03583-y.pdf https://doi.org/10.1007/s11368-023-03583-y,http://dx.doi.org/10.1007/s11368-023-03583-y,,10.1007/s11368-023-03583-y,,,0,001-203-602-931-619; 001-756-393-915-662; 001-920-275-922-716; 001-976-179-016-388; 002-637-840-196-597; 004-067-455-829-678; 004-905-754-748-691; 005-294-722-309-586; 005-792-905-174-516; 006-729-446-743-357; 009-415-560-471-233; 009-542-917-522-403; 009-595-615-037-487; 010-524-091-465-049; 011-622-884-541-932; 012-056-231-518-308; 012-319-621-190-477; 013-389-316-182-243; 013-398-882-755-215; 013-507-404-965-47X; 014-113-586-907-020; 014-221-622-053-164; 014-372-606-756-597; 014-779-848-166-906; 018-897-875-070-187; 019-446-041-507-163; 019-759-269-996-36X; 020-372-532-610-92X; 020-525-160-830-693; 022-924-192-524-544; 023-082-400-910-035; 025-824-073-023-326; 026-664-372-213-599; 028-308-271-090-499; 029-393-259-049-085; 031-713-878-599-766; 032-018-334-598-433; 033-275-685-585-38X; 033-590-296-133-937; 035-187-818-193-455; 035-641-275-286-301; 036-419-978-820-530; 038-032-722-504-530; 038-522-431-225-699; 038-717-845-292-867; 041-040-502-432-06X; 042-503-961-286-692; 043-119-809-813-195; 043-257-808-866-186; 043-666-188-465-396; 043-708-170-473-892; 044-403-633-558-374; 044-543-013-307-106; 045-562-309-932-867; 045-848-328-286-518; 046-908-929-290-609; 047-173-142-320-888; 049-500-802-526-311; 049-587-861-179-158; 049-716-847-263-191; 050-750-482-286-896; 051-381-272-512-133; 052-629-455-206-262; 054-222-405-602-652; 054-661-577-174-695; 058-497-078-863-158; 058-535-290-272-704; 058-928-948-002-434; 058-979-337-075-001; 060-551-000-401-873; 060-714-863-104-368; 061-926-646-039-695; 064-343-216-976-747; 067-759-364-357-102; 068-371-633-724-376; 068-382-158-521-935; 068-924-211-917-394; 069-334-777-950-966; 069-511-868-544-95X; 069-536-153-435-355; 069-820-152-784-711; 072-932-787-870-95X; 073-540-663-870-046; 074-966-535-267-570; 075-968-844-555-424; 076-563-643-386-653; 080-695-942-274-888; 080-787-222-569-045; 083-100-631-801-55X; 084-133-911-161-427; 085-339-823-426-368; 086-880-702-998-679; 086-901-363-488-091; 087-334-337-595-748; 088-614-313-955-596; 091-554-285-821-457; 091-753-633-632-647; 092-080-577-478-456; 092-317-151-656-887; 096-270-220-359-254; 097-117-527-414-946; 098-891-236-855-943; 103-856-359-286-272; 104-195-827-111-408; 106-185-446-772-337; 110-186-600-879-749; 114-517-968-516-726; 115-464-752-292-225; 116-435-067-295-464; 117-112-341-208-838; 118-435-713-463-753; 118-460-080-038-89X; 119-997-819-899-572; 123-504-991-583-496; 123-640-861-767-103; 125-097-525-529-158; 128-784-754-496-023; 130-713-019-240-308; 131-279-274-664-754; 135-272-715-255-993; 140-787-677-664-57X; 142-398-788-578-256; 146-228-873-706-64X; 150-352-524-015-210; 151-650-367-779-832; 155-914-579-503-258; 157-689-153-929-061; 167-531-229-442-544; 172-406-284-795-922; 187-680-417-866-138,5,true,cc-by,hybrid -112-555-329-574-537,Financial Communication in Crisis Situations,2024-12-23,2024,journal article,Studies and Scientific Researches. Economics Edition,23441321; 2066561x,Vasile Alecsandri University of Bacau,,Anatol Melega; Veronica Grosu; Corina Petrescu,"Financial communication plays a key role in shaping stakeholders' decision-making processes, acquiring even greater importance in today's turbulent global landscape marked by various overlapping crises. Thus, the aim of the research revolves around a theoretical exploration, supported by a bibliometric analysis, to emphasize the intrinsic importance of financial communication. The research methodology is based on a bibliometric analysis of 3,000 scientific papers indexed in the Web of Science database, from 1975 to 2023, focusing on financial communication. To facilitate this analysis, specialized software tools for data processing and bibliometric exploration, namely VOSviewer and Bibliometrix, were used. The research findings underline the complexity and interdependence of the financial communication process in organizations, highlighting its evolution from transparency and reduction of information asymmetry in periods of stability, to the need for rapid adoption of digital technologies and integration of ESG dimensions during recent crises, all of which are essential to meet stakeholders' demands and maintain investors' trust. ",,40,,,Transparency (behavior); Finance; Investor relations; Financial services; Process (computing); Financial crisis; Business; Knowledge management; Accounting; Computer science; Economics; Marketing; Strategic management; Computer security; Macroeconomics; Operating system,,,,,,http://dx.doi.org/10.29358/sceco.v0i40.589,,10.29358/sceco.v0i40.589,,,0,,0,true,cc-by,gold -112-701-804-758-726,Hotspots and frontiers of autophagy and chemotherapy in lung cancer: a bibliometric and visualization analysis from 2003 to 2023.,2024-08-09,2024,journal article,Naunyn-Schmiedeberg's archives of pharmacology,14321912; 00281298,Springer Science and Business Media LLC,Germany,Minghe Lv; Yue Feng; Su Zeng; Yang Zhang; Wenhao Shen; Wenhui Guan; Xiangyu E; Hongwei Zeng; Ruping Zhao; Jingping Yu,,398,2,1583,1595,Lung cancer; Autophagy; Chemotherapy; China; Medicine; Cancer; Oncology; Cancer research; Library science; Internal medicine; Biology; Geography; Computer science; Apoptosis; Biochemistry; Archaeology,Autophagy; Bibliometrics; Chemotherapy; Lung cancer,Animals; Humans; Antineoplastic Agents/therapeutic use; Autophagy/drug effects; Bibliometrics; Lung Neoplasms/drug therapy,Antineoplastic Agents,Science and technology development project of Shanghai University of Traditional Chinese Medicine (23KFL105); the Integrated Chinese and western medicine project of Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine (SGZXY-202201); the Shanghai Health Commission (202340160),,http://dx.doi.org/10.1007/s00210-024-03354-7,39120721,10.1007/s00210-024-03354-7,,,0,002-052-422-936-00X; 002-226-739-520-94X; 004-922-032-564-764; 005-389-787-220-058; 006-511-842-258-511; 007-500-155-247-91X; 021-070-205-626-900; 021-161-718-477-633; 022-197-130-964-220; 022-889-800-340-116; 024-044-775-967-248; 024-730-564-155-207; 030-970-234-454-757; 036-840-754-482-439; 038-992-139-714-379; 039-308-434-149-512; 040-803-060-154-176; 041-955-434-134-655; 052-347-537-979-132; 057-409-890-405-028; 059-834-750-574-823; 060-897-758-234-667; 062-803-314-841-485; 064-400-499-357-900; 071-090-286-864-100; 072-042-364-654-214; 073-921-477-712-174; 078-844-256-606-71X; 080-977-108-232-315; 081-808-294-510-946; 083-431-096-605-536; 099-357-312-335-533; 110-265-677-688-073; 111-731-344-760-876; 112-176-766-467-406; 115-206-984-034-178; 123-202-581-406-928; 129-500-194-861-975; 131-251-960-441-935; 133-039-274-591-217; 139-862-831-400-807; 167-373-519-239-682,2,false,, -112-823-418-721-699,The period of insect research in the tropics: a bibliometric analysis,2021-09-09,2021,journal article,International Journal of Tropical Insect Science,17427592,Springer Science and Business Media LLC,,M. C. Moshobane; T. T. Khoza; S. Niassy,"The International Journal of Tropical Insect Science (Int J Trop Insect Sci) is a peer-reviewed journal established in 1980 to promote insect science mainly in the tropics. This study aimed to provide a Bibliometric overview of Int J Trop Insect Sci publications and citations between 2012 and 2020, ending September 2020. A sample of 488 documents extracted from the Web of Science (WoS) was analysed using widely used bioclimatic indicators. The articles were written by 1726 authors. During this period, the most productive authors comprised S Roy, followed by S Ekesi, S Subramanian and M Tamo. The dominant keyword was ‘resistance’, followed by ‘Homoptera'. India took a leading position in Single Country Publications (SCP) while Kenya took the lead in Multiple Country Publications (MCP). Bibliometric analysis reveals vibrant collaboration between African and Western countries and active publication of multi-country authored articles. We conclude that there is an increasing trend for collaboration among different countries on the general topic of insect science. Research in insect science has the potential to impact both academic researchers and practitioners the knowledge use chain. This study will help researchers, journal editors, science policy makers managers, and others working in the biodiversity space and potential research gaps needing for further studies.",42,1,989,998,,,,,,,http://dx.doi.org/10.1007/s42690-021-00616-2,,10.1007/s42690-021-00616-2,,,0,000-151-054-454-779; 000-357-024-107-673; 002-052-422-936-00X; 004-667-845-742-155; 007-204-801-138-560; 007-619-374-847-390; 011-200-641-693-405; 012-089-357-169-722; 013-507-404-965-47X; 015-692-170-714-052; 017-750-600-412-958; 019-382-164-002-026; 019-903-293-066-035; 021-837-341-955-398; 023-927-221-065-800; 027-651-907-807-654; 028-805-520-529-245; 029-696-356-795-74X; 030-630-494-577-373; 033-411-261-739-529; 034-768-039-318-254; 036-533-103-548-545; 037-094-856-462-847; 037-815-640-424-494; 040-166-121-939-737; 040-441-600-560-680; 041-026-122-912-036; 041-033-829-609-028; 043-220-284-338-104; 046-974-890-723-176; 048-334-746-448-891; 050-371-256-500-33X; 051-446-526-868-653; 052-099-096-702-452; 057-600-288-312-641; 058-419-031-020-969; 062-125-807-687-084; 071-111-301-281-406; 072-596-609-644-132; 081-483-203-921-617; 084-096-957-668-741; 084-673-054-867-296; 088-983-454-345-883; 104-591-003-715-334; 105-658-758-342-150; 109-507-505-658-699; 115-218-772-115-767; 117-094-720-234-570; 120-189-345-815-057; 123-202-581-406-928; 126-534-231-283-163; 133-160-286-607-487; 135-458-488-286-663; 138-425-890-771-112; 148-419-446-362-330; 158-248-171-252-43X; 159-471-203-985-186; 179-490-910-367-466,10,true,,green -113-025-399-927-383,MAPA CIENTÍFICO POR ANÁLISE BIBLIOMÉTRICA DA SINERGIA ENTRE SIMULAÇÃO BASEADA EM AGENTES E LOGÍSTICA URBANA UTILIZANDO BIBLIOMETRIX,2022-10-10,2022,conference proceedings article,Anais do Encontro Nacional de Engenharia de Produção,23183349,ENEGEP 2022 - Encontro Nacional de Engenharia de Produção,,JOSÉ DA SILVA FERREIRA JUNIOR; ALEXANDRE FERREIRA DE PINHO; JOSIANE PALMA LIMA,,,,,,Humanities; Materials science; Physics; Geomorphology; Philosophy; Geology,,,,,http://www.abepro.org.br/biblioteca/TN_ST_383_1896_43937.pdf https://doi.org/10.14488/enegep2022_tn_st_383_1896_43937,http://dx.doi.org/10.14488/enegep2022_tn_st_383_1896_43937,,10.14488/enegep2022_tn_st_383_1896_43937,,,0,,0,true,,bronze -113-331-192-012-35X,"Análisis bibliométrico de la producción científica de las universidades estatales de Costa Rica indexadas en Scopus, 2011-2019: una aplicación con el paquete de lenguaje R ""Bibliometrix""",2022-01-24,2022,journal article,Bibliotecas,16593286; 14093049,Universidad Nacional de Costa Rica,,Silvia Sáenz León; Nanci Rodríguez Ramos,"El presente artículo está orientado al análisis de algunos indicadores bibliométricos, aplicados a la producción científica realizada por las universidades estatales de Costa Rica para el período 2011-2019. Mediante el lenguaje en R y el uso de la aplicación Biblioshiny de la librería/paquete Bibliometrix, se generó una serie de indicadores relacionados con la productividad por autor, afiliación, nivel de citación, entre otras características documentales, consumo científico e impacto.; Entre los principales hallazgos se evidencia que la mayor parte de la producción científica de Costa Rica, indexada en Scopus, proviene de las universidades estatales; hay presencia de la investigación costarricense en todos los continentes y no únicamente como participantes, sino como líderes o investigadores principales; existe gran diversificación de publicación en revistas de múltiples disciplinas; y hay diversidad de investigación en múltiples áreas de la ciencia, entre otros.",40,1,1,25,Humanities; Political science; Philosophy,,,,,https://www.revistas.una.ac.cr/index.php/bibliotecas/article/download/16627/24318 https://doi.org/10.15359/rb.40-1.1,http://dx.doi.org/10.15359/rb.40-1.1,,10.15359/rb.40-1.1,,,0,,2,true,cc-by-nc-nd,gold -113-372-979-057-536,A Critical Appraisal of Review Studies in Circular Economy: a Tertiary Study,2021-10-25,2021,journal article,Circular Economy and Sustainability,2730597x; 27305988,Springer Science and Business Media LLC,,Marcelo Werneck Barbosa,"The importance of the circular economy has greatly increased in the past few years, and consequently, the interest in the circular economy as a research field has also increased, which led to an exponential growth in the number of literature reviews on the subject with different purposes. In order to analyze the topics that have been studied and assess the quality of these secondary reviews, this study carried out a tertiary literature review on the subject. This study identified the literature reviews on the circular economy, the most frequently cited papers, and the main research topics in the field. We have also analyzed the types of research questions that have been proposed by secondary studies. Finally, we evaluated the extent to which secondary reviews have assessed the quality of primary studies. We found out that literature reviews on the circular economy are frequently related to the areas of supply chain and technology. We also concluded that there is a need for designing research questions that explore more complex relationships, since most questions are descriptive or process-related. Some research questions are proposed to guide future studies. We also observed that secondary studies have failed to appropriately assess the quality of primary studies.",2,2,473,505,,,,,,,http://dx.doi.org/10.1007/s43615-021-00123-z,,10.1007/s43615-021-00123-z,,,0,000-209-413-168-336; 000-295-333-578-291; 000-357-362-918-727; 001-042-196-746-893; 001-103-577-448-431; 001-896-291-672-879; 002-052-422-936-00X; 003-063-623-571-131; 003-702-278-943-595; 003-983-869-771-688; 007-424-954-971-689; 007-784-009-825-643; 008-156-679-024-430; 009-365-584-908-011; 010-125-276-267-93X; 010-977-783-106-567; 011-424-347-563-258; 012-305-836-277-353; 013-100-163-129-555; 013-507-404-965-47X; 013-723-565-072-951; 015-101-574-812-09X; 016-293-547-479-557; 016-334-627-541-451; 017-695-524-061-041; 017-963-679-507-851; 018-529-065-706-391; 019-381-776-470-141; 020-137-487-696-356; 020-171-792-629-458; 020-345-031-753-320; 020-604-839-643-865; 021-147-163-774-894; 022-136-834-373-534; 024-127-144-509-711; 025-111-295-042-100; 025-526-746-994-149; 026-619-319-410-128; 027-834-418-786-698; 029-837-794-329-040; 030-004-164-307-225; 030-601-865-733-53X; 031-173-193-337-136; 032-417-695-004-571; 033-965-786-944-095; 034-832-104-828-896; 038-740-855-920-965; 039-322-835-791-54X; 039-593-089-490-511; 040-520-960-023-817; 040-575-485-698-185; 041-030-293-141-151; 041-347-179-206-359; 041-359-911-734-995; 042-131-804-695-99X; 042-228-490-689-212; 042-320-898-246-425; 044-518-574-739-481; 044-592-141-889-981; 044-832-507-036-626; 045-368-114-501-494; 045-667-406-743-903; 045-716-736-824-368; 046-327-740-842-435; 046-366-778-970-688; 048-292-735-731-613; 051-712-291-523-51X; 053-718-607-482-575; 055-528-415-385-143; 055-831-453-004-577; 057-725-975-009-264; 057-939-078-130-009; 058-978-696-293-815; 059-272-966-170-236; 060-778-695-985-858; 062-389-339-969-687; 063-108-191-443-488; 066-157-822-409-471; 067-804-225-015-612; 067-950-923-597-803; 067-975-723-728-662; 069-428-700-193-626; 069-483-122-357-490; 069-568-717-641-59X; 070-694-964-750-489; 071-002-707-690-91X; 071-154-908-420-986; 071-832-604-383-338; 072-729-284-235-539; 073-236-513-589-340; 073-907-067-828-667; 074-558-366-735-659; 075-945-628-035-860; 077-023-263-207-755; 077-695-811-773-259; 077-744-231-077-191; 078-198-299-095-581; 079-928-195-279-966; 080-349-990-982-940; 080-534-604-540-592; 083-512-255-064-365; 083-587-760-666-654; 084-393-427-594-838; 084-780-559-430-325; 085-300-287-100-525; 087-367-774-861-953; 088-427-145-755-953; 089-476-021-281-458; 090-316-422-321-492; 091-468-545-338-541; 093-010-160-709-442; 093-792-038-361-891; 094-920-829-297-363; 095-536-947-766-327; 096-904-868-858-373; 097-883-389-716-956; 099-016-262-804-489; 099-891-607-594-233; 100-445-029-445-191; 101-773-162-602-888; 106-044-783-257-556; 106-422-783-295-072; 107-135-946-887-529; 107-385-428-834-04X; 107-784-487-222-826; 108-281-336-048-551; 109-080-300-124-642; 110-778-384-799-718; 111-151-955-415-990; 113-616-602-187-101; 114-539-296-954-404; 116-233-042-995-880; 117-908-473-132-381; 118-393-650-963-36X; 120-448-395-343-821; 121-807-185-503-768; 122-778-325-216-063; 123-765-939-982-794; 124-006-582-410-441; 124-793-152-887-202; 125-718-889-353-551; 125-855-833-392-181; 139-469-129-684-589; 141-949-097-009-187; 143-655-125-023-189; 144-884-533-652-481; 160-678-479-682-243; 161-631-555-840-855; 162-149-384-399-356; 162-870-715-278-561; 163-240-554-393-20X; 169-998-850-032-027; 184-983-080-842-358,9,true,,bronze -113-932-810-299-09X,Bibliometric Analysis of a Comprehensive of Culture and Symbol in Character Animation during (2004–2024),2024-08-24,2024,journal article,Journal of Ecohumanism,27526801; 27526798,Creative Publishing House,,Chen Yang; Siti Salmi Jamali; Adzira Husain,"The analysis of academic research on animated characters in the animation industry effectively summarises the current state of scholarly research on animated characters through a variety of software tools such as CiteSpace, VOS viewer, HistCite, and Bibliometrix analysis, and visually charts and formulates this data. Through study and research, it that the United States is (278) the most prolific country, and the United States has the highest intermediary centrality, as well as the most Centre National de la Recherche Scientifique (CNRS) and PEOPLES R CHINA are the most cited organizations and Countries/Regions with the highest intermediary centrality and Countries/Regions with the highest citation explosiveness, respectively. This study also suggests possible challenges and future directions in character design for animated characters.",3,3,1427,1458,Character (mathematics); Animation; Centrality; Variety (cybernetics); Symbol (formal); China; Citation; Computer science; Library science; History; Computer graphics (images); Archaeology; Artificial intelligence; Mathematics; Geometry; Combinatorics; Programming language,,,,,https://ecohumanism.co.uk/joe/ecohumanism/article/download/3821/3027 https://doi.org/10.62754/joe.v3i3.3821,http://dx.doi.org/10.62754/joe.v3i3.3821,,10.62754/joe.v3i3.3821,,,0,,0,true,cc-by-nc-nd,hybrid -114-252-152-616-942,Economic Integration in Latin America: An Approach Through the Analysis of Biblio­metric Indicators on Research Production,2022-12-22,2022,journal article,Organizations and Markets in Emerging Economies,23450037; 20294581,Vilnius University Press,Latvia,William A. Malpica Zapata; Víctor Hugo Nauzan Ceballos; Leidy Maritza Silva Rodríguez,"This article analyzes different bibliometric indicators on research papers which examine the issue of economic integration in the Latin American region. The documents have been obtained from the Scopus bibliographic database; a total of 564 papers published in the time span from 2000 to 2020 have been identified, processed, and analyzed using the open-source software Bibliometrix and Vos Viewer. The results achieved allow identifying elements such as volume and relevance in scientific publications by country, H-G-M index of researchers with the greatest impact, estimation of Lotka’s Law, the analysis of co-occurrence between keywords, the dynamics in publication of the main sources, and finally, the thematic evolution in the last two decades. The findings provide a better understanding of the research processes as well as a comprehensive analysis of authors, their impact and the relevant sources in the economic integration of Latin America.",13,2,300,316,Scopus; Latin Americans; Relevance (law); Regional science; Data science; Thematic map; Metric (unit); Computer science; Library science; Political science; Geography; Economics; Cartography; Operations management; MEDLINE; Law,,,,,https://www.journals.vu.lt/omee/article/download/25518/29183 https://doi.org/10.15388/omee.2022.13.81,http://dx.doi.org/10.15388/omee.2022.13.81,,10.15388/omee.2022.13.81,,,0,002-814-104-469-520; 004-474-578-442-973; 009-552-317-724-166; 012-923-375-588-244; 013-507-404-965-47X; 014-224-407-983-207; 024-158-376-455-89X; 028-649-018-558-073; 037-458-155-285-731; 040-370-425-078-321; 045-517-918-499-023; 046-992-864-415-70X; 050-893-374-534-416; 058-370-709-813-264; 065-348-244-810-815; 067-136-454-648-471; 068-752-052-168-139; 088-954-742-996-418; 093-116-925-441-579; 094-933-689-964-461; 101-810-305-818-353; 106-979-362-871-316; 108-083-773-443-018; 109-231-717-269-391; 112-533-001-418-656; 118-847-772-934-587; 127-968-398-610-781; 135-023-238-786-005; 135-689-969-972-312,2,true,cc-by,gold -114-455-050-122-773,"The impact of high-density urban environments on children's play, a systematic review of current insights",2025-01-03,2025,journal article,Cities & Health,23748834; 23748842,Informa UK Limited,,Pengyu Lu; Jeroen van Ameijde,"Amongst ongoing urban densification, urban environments are increasingly lacking adequate and well-connected play spaces. While studies into child-friendly cities have focused on low-density urban areas, this study gathers different insights on the perception of high-density urban environments and children's play. Using the Bibliometrix R-Tool, the study identified significant potential relationships in the literature on children's play spaces, children's well-being and built environment characteristics. Synthesizing research from various countries, we summarize the current insights around assessing the quality of children's play spaces. This approach can provide guidance to create improved play spaces, as part of more sustainable and liveable compact cities.",,,1,20,Perception; Quality (philosophy); Built environment; Urban environment; Geography; Environmental planning; Psychology; Civil engineering; Engineering; Epistemology; Philosophy; Neuroscience,,,,,,http://dx.doi.org/10.1080/23748834.2024.2441554,,10.1080/23748834.2024.2441554,,,0,000-225-543-572-396; 000-372-249-774-00X; 001-181-208-891-140; 002-448-203-317-912; 002-827-721-722-248; 003-909-881-020-937; 004-945-025-530-293; 005-783-266-169-694; 009-009-911-289-844; 009-281-703-581-376; 009-518-767-226-202; 010-065-762-504-134; 010-351-304-491-628; 013-054-672-403-554; 013-507-404-965-47X; 013-675-284-731-566; 014-317-068-161-702; 014-965-806-636-518; 016-873-600-445-948; 017-291-515-449-588; 018-902-034-104-796; 018-972-374-195-050; 019-266-679-727-343; 020-342-476-976-048; 022-006-232-330-97X; 022-390-583-439-44X; 024-381-787-695-312; 024-620-013-647-793; 024-982-288-838-837; 026-021-959-892-093; 026-138-149-302-003; 027-229-619-142-13X; 029-985-761-464-611; 040-481-018-231-570; 041-752-198-019-785; 041-994-023-340-43X; 044-232-051-596-414; 044-376-607-084-901; 044-944-626-642-131; 045-198-717-003-751; 045-780-742-405-043; 046-377-118-895-954; 046-745-538-772-80X; 047-762-307-555-462; 050-548-686-711-226; 050-587-849-367-282; 054-351-697-674-738; 054-884-332-795-053; 055-551-121-786-457; 057-968-719-702-824; 063-370-543-186-715; 065-010-405-236-060; 065-760-720-221-881; 065-857-836-337-414; 066-339-673-922-219; 066-752-467-302-157; 067-361-735-302-443; 070-718-880-103-974; 076-088-167-737-52X; 078-482-004-735-237; 081-230-381-986-098; 081-492-528-673-484; 091-292-769-679-349; 093-929-704-321-176; 094-032-075-150-959; 096-074-011-014-892; 098-213-516-458-157; 099-001-855-243-363; 105-596-083-036-487; 106-472-493-772-702; 111-615-319-732-621; 115-456-616-166-654; 117-420-412-082-705; 121-222-072-298-071; 123-721-749-316-411; 124-190-018-428-803; 124-222-444-170-765; 125-484-711-389-013; 125-617-598-263-30X; 127-245-670-262-773; 128-517-099-235-559; 128-652-060-385-543; 129-301-333-877-300; 129-356-396-741-740; 129-605-614-338-648; 135-896-038-855-486; 142-704-514-147-611; 143-630-689-151-783; 149-218-792-658-156; 156-279-676-077-39X; 167-912-133-905-996; 168-339-598-110-509; 168-733-589-796-970; 169-162-120-968-878; 179-083-719-555-647; 187-881-724-436-753,0,true,cc-by-nc-nd,hybrid -115-256-283-674-813,Scientific Mapping Example with R package `bibliometrix`,2023-11-07,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,José Rafael Caro Barrera,Example of the use of the R package bibliometrix for bibliometric analysis,,,,,R package; Computer science; Programming language,,,,,https://zenodo.org/doi/10.5281/zenodo.10079724,http://dx.doi.org/10.5281/zenodo.10079724,,10.5281/zenodo.10079724,,,0,,0,false,, -115-310-980-105-848,Impact of perioperative dexmedetomidine on postoperative delirium in adult undergoing cardiac surgery: A comprehensive bibliometrix and meta-analysis.,2025-05-03,2025,journal article,Asian journal of psychiatry,18762026; 18762018,Elsevier BV,Netherlands,Qiang Fu; Bhushan Sandeep; Hong Li; Bao San Wang; Xin Huang,,108,,104522,104522,Dexmedetomidine; Delirium; Perioperative; Medicine; Meta-analysis; Anesthesia; Cardiac surgery; Surgery; Intensive care medicine; Sedation; Internal medicine,Bibliometrix; Cardiac surgery; Dexmedetomidine; Meta-analysis; Postoperative delirium,Humans; Dexmedetomidine/pharmacology; Cardiac Surgical Procedures/adverse effects; Hypnotics and Sedatives/pharmacology; Postoperative Complications/prevention & control; Delirium/prevention & control; Emergence Delirium/prevention & control; Perioperative Care; Randomized Controlled Trials as Topic,Dexmedetomidine; Hypnotics and Sedatives,,,http://dx.doi.org/10.1016/j.ajp.2025.104522,40339195,10.1016/j.ajp.2025.104522,,,0,005-438-538-049-075; 006-925-144-474-882; 008-788-234-990-201; 010-699-542-755-016; 012-135-156-245-834; 013-402-156-072-929; 015-142-162-177-254; 019-945-163-587-217; 020-154-539-566-751; 025-437-077-382-844; 026-891-019-566-297; 028-207-838-228-645; 030-428-182-489-033; 033-099-539-558-05X; 039-995-091-485-393; 048-110-216-978-585; 048-441-928-784-419; 049-870-322-903-534; 050-112-806-905-141; 056-507-081-247-050; 057-878-137-379-60X; 058-274-469-222-149; 058-311-679-149-744; 059-043-666-001-562; 066-459-523-848-355; 069-044-685-310-376; 078-656-251-236-379; 079-743-295-655-956; 081-605-123-600-744; 089-446-030-409-559; 091-689-250-814-570; 093-916-380-041-094; 105-036-882-638-50X; 127-833-168-539-31X; 138-082-886-075-905; 140-572-843-186-625; 144-083-532-547-161; 147-061-293-906-172; 149-079-498-302-549; 183-399-562-379-31X; 191-671-625-932-726,0,false,, -115-900-204-040-754,Trends in Colorectal Cancer Peritoneal Metastases Research: A Comprehensive Bibliometric Analysis.,2025-01-23,2025,journal article,Journal of gastrointestinal cancer,19416636; 19416628,Springer Science and Business Media LLC,United States,Yuzhe Zhang; Zi Jin; Zhongqing Wang; Lirong Yan; Aoran Liu; Fang Li; Yanke Li; Ye Zhang,,56,1,51,,Medicine; Colorectal cancer; Radiation therapy; Oncology; Internal medicine; Medical physics; General surgery; Cancer,Bibliometric; Colorectal cancer; Peritoneal metastases; Trial,Humans; Colorectal Neoplasms/pathology; Peritoneal Neoplasms/secondary; Bibliometrics; Biomedical Research/trends,,National Natural Science Foundation of China (82073244); Shenyang Youth Science and Technology Innovation Talent Project (RC200267),,http://dx.doi.org/10.1007/s12029-025-01176-1,39847239,10.1007/s12029-025-01176-1,,,0,000-175-601-670-945; 000-328-755-179-395; 002-052-422-936-00X; 003-939-453-492-011; 005-007-596-121-261; 010-883-882-280-889; 011-677-423-199-941; 012-925-903-739-130; 013-507-404-965-47X; 016-127-240-699-391; 017-041-524-344-399; 019-988-556-983-288; 023-854-450-314-992; 024-297-353-475-994; 024-389-756-061-751; 030-894-960-444-658; 032-466-683-841-437; 032-621-596-207-54X; 033-941-505-101-563; 035-080-915-676-491; 035-913-488-102-728; 036-656-168-693-890; 037-326-361-046-26X; 037-605-698-421-653; 038-161-895-845-123; 041-286-978-211-588; 044-876-735-991-902; 050-446-632-398-935; 050-956-930-367-934; 052-431-228-304-459; 055-081-092-883-165; 063-626-988-317-112; 070-653-996-446-018; 071-280-078-989-133; 072-545-082-313-651; 075-472-270-113-301; 079-649-099-240-293; 087-550-125-834-272; 088-708-444-447-185; 091-378-364-292-944; 097-648-974-741-511; 099-067-393-641-886; 114-630-276-231-054; 118-500-046-037-838; 121-953-635-826-413; 122-232-160-162-145; 122-390-150-756-744; 132-805-665-548-500; 164-440-122-066-558; 168-975-082-987-067; 198-123-839-918-134,2,false,, -115-990-859-413-146,CONSUMER XENOCENTRISM: BIBLIOMETRIC ANALYSIS with RSTUDIO,2023-10-09,2023,journal article,Finans Ekonomi ve Sosyal Araştırmalar Dergisi,26022486,Finans Ekonomi ve Sosyal Arastirmalar Dergisi,,Pınar YÜRÜK KAYAPINAR,"The aim of this study is to show the status of the publications on consumer xenocentrism, which has a limited number of publications, to examine the methodological dimension, to reveal the trend and future aspects of the concept. For this reason, bibliometric analysis was performed using biblioshiny in the bibliometrix program in RStudio. The publications on the concept in WoS and Scopus databases between the years 2013-2023 were examined. 49 documents were obtained from 36 sources. Results are given at five different levels: documents, authors, affiliations, countries, sources. According to the results, almost all the studies on the concept are related to the consumer behavior literature in the field of marketing. An increase has been observed in studies on the subject, especially in recent years. Most of these studies are based on the quantitative method. There are no studies with qualitative methods. Another result is that there is no study conducted in Turkey in these databases.",8,3,814,827,Scopus; Bibliometrics; Dimension (graph theory); Subject (documents); Computer science; Political science; Library science; Mathematics; MEDLINE; Pure mathematics; Law,,,,,,http://dx.doi.org/10.29106/fesa.1302809,,10.29106/fesa.1302809,,,0,002-903-745-679-063; 005-409-395-948-360; 005-894-886-777-430; 010-065-762-504-134; 020-869-475-801-642; 023-335-956-990-424; 023-966-172-369-999; 025-421-093-942-075; 026-806-951-395-834; 029-474-209-599-163; 031-535-330-793-724; 034-475-986-737-79X; 035-854-849-551-880; 036-557-930-460-738; 036-659-005-806-663; 046-992-864-415-70X; 053-197-256-373-949; 057-641-951-771-977; 057-745-371-329-863; 064-158-745-887-681; 064-742-234-216-07X; 066-093-645-307-369; 067-957-153-938-246; 092-941-152-143-45X; 096-155-280-351-568; 100-542-348-054-926; 101-493-457-050-535; 102-838-974-401-396; 120-431-329-242-490; 130-139-363-644-316; 148-681-397-145-252; 155-990-105-106-562,0,true,,gold -116-115-992-833-482,Assessing the Realization of Global Land Restoration: A Meta-analysis,2022-03-21,2022,journal article,Anthropocene Science,27313980,Springer Science and Business Media LLC,,Sheikh Adil Edrisi; Priyanka Sarkar; Jaewon Son; Nagaraja Tejo Prakash; Himlal Baral,"Restoring degraded land is essential for regaining ecosystem services (ES) and attaining the UN-Sustainable Development Goals by 2030. Unfortunately, 24% of the global lands are degraded, significantly affecting the lives of 3.2 billion people worldwide. Therefore, innovative restoration practices are vital during ‘UN-Decade on Ecosystem Restoration.’ A meta-analysis of 2093 documents on land degradation and restoration was conducted in this context, and 117 empirical studies were analyzed in detail. These studies were based on the different drivers of land degradation as per the criteria of IPBES and IPCC, respectively. Results suggested that woodland encroachment (18.25%), cropland expansion (18.11%), species loss/compositional shifts (16.06%), climatic factors (14.96%), infrastructure development/urbanization (14.17%), water erosion (13.87%), wind erosion (9.49%) and other demographic pressures (8.66%) were the significant drivers of land degradation. Interestingly, there was a continent-wide change in the critical drivers of land degradation and depleting ES. The infrastructure development/urbanization, demography, and economic attributes were the essential drivers in Asia–Pacific and African regions. In contrast, the fire-regime shift and invasiveness were the significant drivers in Europe, and the climatic attribute was the crucial driver in the Americas. Out of the 117 studies selected worldwide, some ongoing restoration efforts had little emphasis on research-driven on-site restoration for improving different ES. Furthermore, some restoration projects lack proper stakeholder involvement thereby, fail to attract large-scale public acceptance. Moreover, only 12.8% of the studies focused on improving the ES in highly degraded lands. Therefore, this meta-analysis suggests that site-specific, research-driven, and on-site restoration strategies coupled with proper stakeholder engagement are imperative for regaining the ES and functions of the degraded landscape to attain UN-SDG.",1,1,179,194,Restoration ecology; Urbanization; Land degradation; Environmental resource management; Woodland; Context (archaeology); Stakeholder; Environmental planning; Environmental degradation; Climate change; Land management; Ecosystem services; Geography; Sustainable development; Scale (ratio); Land use; Environmental protection; Ecosystem; Environmental science; Ecology; Political science; Public relations; Archaeology; Cartography; Biology,,,,,https://link.springer.com/content/pdf/10.1007/s44177-022-00018-0.pdf https://doi.org/10.1007/s44177-022-00018-0,http://dx.doi.org/10.1007/s44177-022-00018-0,,10.1007/s44177-022-00018-0,,,0,006-504-891-718-195; 006-790-406-664-307; 014-098-136-844-891; 016-598-852-251-468; 017-067-388-248-284; 025-256-247-385-915; 027-059-338-389-006; 029-110-276-740-086; 029-290-542-243-308; 034-436-849-550-644; 040-680-496-397-948; 045-319-994-780-397; 045-640-944-368-610; 048-226-906-342-845; 056-002-925-128-630; 056-593-710-342-514; 058-923-618-930-227; 060-914-666-894-256; 062-143-226-033-516; 063-140-874-066-001; 063-663-054-349-80X; 064-218-709-360-024; 067-223-675-694-995; 075-829-845-788-65X; 077-128-390-965-429; 083-275-136-684-899; 083-514-306-251-638; 089-424-521-577-138; 089-649-988-271-324; 091-122-072-659-848; 094-313-406-433-074; 097-527-037-235-496; 102-104-346-364-077; 104-702-750-815-944; 105-236-923-128-60X; 105-276-547-689-37X; 105-836-312-693-027; 117-298-791-689-526; 132-413-063-058-747; 134-848-424-195-727; 136-040-411-967-995; 148-673-990-585-62X,9,true,,bronze -116-405-723-564-857,Symantic Literatur Review Riset Etnomatematika Menggunakan Bibliometrix R Studio Bibblioshiny,2024-09-19,2024,journal article,Journal of Islamic Education Studies,29620295,Universitas Islam Jakarta,,Chatarina Febriyanti; Shinta Dwi Handayani; Ari Irawan,"The aim of this literature review is to analyze the trend of development of articles published by Scopus with a time span of 40 years from 1984-2024, as a material for study to forecast research that will be carried out by the next researcher. The method of writing this article uses a semantic literature review with the tools used is bibliometric analysis with R Studio biblioshiny. The stages of analysis activities by collecting articles through Scopus API Key with the keyword Ethnomathmematics found as many as 618 documents from journals, books, book chapters and others. Furthermore, an analysis of the results of data visualization from biblioshiny is carried out. The results of the study found that Indonesia,both authors and institutions, wrote many articles related to ethnomathematics. New themes were found that are relevant for ethnomathematics research that are linked to cryptography, curriculum, augmented reality and others, so that prospective researchers can link ethnomathematics with interdisciplinary studies",3,1,65,72,Studio; Art; Visual arts,,,,,,http://dx.doi.org/10.58569/jies.v3i1.1052,,10.58569/jies.v3i1.1052,,,0,,0,false,, -116-570-087-652-133,Value creation in the wine industry—a bibliometric analysis,2024-01-18,2024,journal article,European Food Research and Technology,14382377; 14382385,Springer Science and Business Media LLC,Germany,Eduardo Sánchez-García; Javier Martínez-Falcó; Bartolomé Marco-Lajara; Nikolaos Georgantzis,"AbstractThe main aim of this study is to analyze the literature pertaining to value creation in the wine industry developed in the last two decades, identifying the main contributors such as leading institutions, authors, and countries, and uncovering the main subfields developed by researchers in this area. Bibliometric methods have been used to carry out this research, particularly the R package Bibliometrix®. The results unveil, besides the most relevant contributors, the main subtopics developed in the field of study. It is concluded that value creation is a key factor of success in the wine industry, playing academic research a leading role in revealing consumer trends, health benefits of wine, grape biodiversity, technological developments applicable to production processes, quality improvements of grapes and wines, sustainable practices, brand positioning and other sources of competitive advantage. This research can be of great significance to researchers, policymakers, and managers in the wine industry.",250,4,1135,1148,Wine; Business; Marketing; Quality (philosophy); Value (mathematics); Competitive advantage; Production (economics); Value creation; Industrial organization; Economics; Computer science; Philosophy; Physics; Epistemology; Machine learning; Optics; Macroeconomics,,,,Universidad de Alicante,https://link.springer.com/content/pdf/10.1007/s00217-023-04451-2.pdf https://doi.org/10.1007/s00217-023-04451-2,http://dx.doi.org/10.1007/s00217-023-04451-2,,10.1007/s00217-023-04451-2,,,0,001-314-354-214-662; 004-504-133-818-506; 005-479-060-417-131; 007-513-795-720-253; 007-911-076-649-810; 011-349-085-604-381; 011-818-811-560-037; 013-375-400-569-574; 013-507-404-965-47X; 014-737-944-308-77X; 022-830-049-973-286; 025-125-370-351-032; 025-471-273-972-525; 027-449-476-127-657; 029-432-396-454-895; 029-582-527-999-304; 030-702-780-496-232; 031-151-983-901-064; 031-456-482-371-218; 032-534-804-058-329; 035-345-399-946-483; 039-180-555-316-153; 040-917-217-284-290; 041-151-832-314-391; 042-429-989-770-192; 043-691-449-326-701; 044-969-636-299-34X; 049-867-701-468-627; 054-855-866-177-038; 059-666-293-292-838; 059-855-882-073-476; 062-056-684-388-052; 063-685-745-177-039; 064-565-091-734-19X; 065-933-266-509-983; 067-516-779-199-031; 068-364-473-343-324; 070-228-717-250-93X; 070-456-354-691-668; 074-279-238-515-510; 075-420-046-510-834; 076-493-485-626-146; 079-210-839-973-978; 084-844-935-699-919; 085-281-915-236-255; 086-954-949-629-735; 088-968-078-870-354; 093-471-672-409-939; 096-061-214-240-715; 099-784-148-828-526; 104-808-618-388-477; 111-276-206-355-176; 112-404-384-444-85X; 118-890-062-583-464; 123-130-043-513-515; 127-822-237-729-579; 129-422-245-973-520; 137-551-108-560-94X; 151-568-976-409-041; 169-008-571-300-337; 171-932-484-966-515; 176-349-028-511-801; 192-374-575-936-053,16,true,cc-by,hybrid -116-659-504-327-632,Sugarcane Harvester: A Bibliometric Review,2023-07-31,2023,journal article,Sugar Tech,09721525; 09740740,Springer Science and Business Media LLC,India,Murilo Battistuzzi Martins; Aldir Carpes Marques Filho; Lucas Santos Santana; Fernanda Pacheco de Almeida Prado Bortlheiro; Kelly Gabriela Pereira da Silva,,25,6,1316,1327,Agricultural engineering; Agriculture; Mechanization; Sustainability; Production (economics); Scopus; Web of science; Bibliometrics; Crop management; Citation; Computer science; Engineering; Geography; Data mining; Library science; Political science; Ecology; Macroeconomics; Archaeology; MEDLINE; Law; Economics; Biology,,,,,,http://dx.doi.org/10.1007/s12355-023-01286-9,,10.1007/s12355-023-01286-9,,,0,001-208-048-215-721; 001-529-234-291-493; 002-052-422-936-00X; 002-377-238-333-378; 003-287-102-647-754; 004-358-306-135-47X; 004-895-123-123-402; 005-246-354-340-101; 006-982-147-308-506; 007-521-976-401-091; 008-110-950-869-921; 009-553-661-154-427; 012-699-574-723-695; 013-123-944-981-275; 013-507-404-965-47X; 014-248-234-962-331; 016-003-667-332-340; 019-943-701-921-755; 020-856-253-874-456; 021-751-577-172-747; 022-081-826-988-779; 022-991-412-180-457; 024-727-235-901-646; 025-691-752-520-483; 030-805-625-039-340; 049-769-613-573-620; 050-012-442-370-28X; 050-211-714-235-041; 054-438-908-632-434; 056-363-090-096-215; 060-229-888-135-807; 060-254-499-312-974; 064-100-346-120-692; 071-423-043-855-413; 072-336-825-261-186; 079-630-216-494-402; 080-493-547-850-528; 082-253-282-567-275; 089-900-729-230-437; 098-197-700-293-869; 100-940-100-708-07X; 101-407-164-255-285; 104-712-687-217-851; 117-873-254-222-400; 118-790-588-061-478; 120-430-329-931-259; 120-975-417-040-341; 131-941-419-394-008; 132-095-608-272-866; 136-349-872-720-122; 139-410-396-830-038; 144-001-216-500-108; 156-519-139-898-213; 171-061-575-437-28X; 172-524-730-703-029; 173-300-703-909-164; 175-025-385-767-808; 176-447-426-887-176; 185-461-410-042-985; 187-327-480-513-127; 197-152-289-896-415,6,false,, -116-742-632-142-998,An Investigation into Artificial Intelligence (AI) in the English as a Foreign Language (EFL) Context,2023-08-30,2023,journal article,International Journal of Educational Spectrum,26675870,International Journal of Educational Spectrum,,Yusuf KASIMİ; Şerife FİDAN,"Using data from Bibliometrix and Web of Science, this study examined articles in the subject of language and linguistics that dealt with artificial intelligence (AI). The study used bibliometrics to uncover historical trends in AI in EFL. The study utilized Biblioshiny, a web-based tool in the bibliometrix package that analyses bibliographic database data, to examine downloaded Web of Science (WoS) data. The Bibliometrix R Package and Biblioshiny software created tables and graphs. The study searched the WoS website for studies with ""Artificial Intelligence (AI)"" in the title, abstract, and keywords to find bibliographic data. From 2013 to 2023, WoS focused on Language and Linguistics in Language Education. There were 1693 EFL AI papers. The study chose open-access publications to read the entire text. The present analysis examined 177 publications. Different bibliometric analysis techniques were employed to get the most usable data from research publications. Authors, publishing years, universities, countries, preferred journals, trendy topics, and keyword citation rates were all considered in the analysis. Findings showed an increase in publications over time and a growing interest in AI. Leading universities and prominent authors were identified. Depending on the country, different levels of engagement were observed. The distribution of data was provided via preferred journals. This study helps researchers and decision-makers evaluate AI research in language and linguistics.",5,2,269,280,Computer science; Publishing; Context (archaeology); Citation; Bibliometrics; Artificial intelligence; Subject (documents); English language; Computational linguistics; Natural language processing; World Wide Web; Data science; Psychology; Mathematics education; Political science; History; Archaeology; Law,,,,,https://dergipark.org.tr/tr/download/article-file/3323056 https://dergipark.org.tr/tr/pub/ijesacademic/issue/76639/1341110,http://dx.doi.org/10.47806/ijesacademic.1341110,,10.47806/ijesacademic.1341110,,,0,003-462-916-914-407; 013-507-404-965-47X; 019-063-900-388-732; 025-203-599-293-476; 026-074-701-392-875; 043-936-646-030-670; 056-595-335-009-339; 068-064-417-946-548; 086-359-684-264-518; 098-520-145-422-381; 106-885-135-974-430; 110-074-171-592-38X; 119-499-631-309-970; 127-112-042-662-021; 139-723-567-366-194,4,true,cc-by-nc,gold -116-750-065-210-439,Evolution and Trend of Deep Learning in Agriculture: A Bibliometric Approach,,2022,journal article,Journal of Computer and Communications,23275219; 23275227,"Scientific Research Publishing, Inc.",,Kimba Sabi N'goye; Henoc Soude; Yêyinou Laura Estelle Loko,"Deep Learning has recently gained a great deal of attention. From this, resulted many applications in a variety of industries, including agriculture. An essential study goal is to understand what has been done in the use of deep learning in agriculture (DLA) thus far in order to establish a robust research agenda to address its future challenges. The present state of research on the DLA with special attention to Africa was evaluated in this study using bibliometric analysis. A search of documents dealing with DLA was realized in the Web of Science database, a world-leading publisher-independent global citation database. A bibliometric program named Bibliometrix was used to examine the data after the search yielded 3207 items. Key findings are highlighted and discussed, and then some directions for potential future research are suggested.",10,12,113,124,Web of science; Agriculture; Data science; Variety (cybernetics); Computer science; Citation; Bibliometrics; Citation analysis; Artificial intelligence; Political science; Geography; World Wide Web; MEDLINE; Archaeology; Law,,,,,http://www.scirp.org/journal/PaperDownload.aspx?paperID=122235 https://doi.org/10.4236/jcc.2022.1012009,http://dx.doi.org/10.4236/jcc.2022.1012009,,10.4236/jcc.2022.1012009,,,0,013-507-404-965-47X; 026-277-757-182-201; 027-341-439-641-150; 043-689-367-508-20X; 096-952-924-281-81X,1,true,,gold -116-776-408-799-229,A Bibliometric Analysis of Syrian Refugees with VOSviewer and Rstudio Bibliometrix Software Tools,2024-07-20,2024,journal article,Middle East Journal of Refugee Studies,21494398; 24588962,Uluslararası Mülteci Hakları Derneği,,Halim Baş,"The aim of the study is to examine in detail the scientific processes of the 2011 civil war in Syria and the subsequent developments in articles on the concept of Syrian refugees between 2013 and 2024. The situation of the Syrian population, which is spread across many different countries, has resulted in numerous scientific studies and has been studied in different dimensions. Performance analysis, scientific mapping and bibliometric analysis were carried out using the VOS viewer (1.6.18) and bibliometrix, a tool in the R studio software package. The sample area of the research consists of 2197 papers obtained from the Web of Science database and limited by article. The results show that the broadcasting process, which began in 2013, has gained momentum since 2017 and peaked in 2021. The most commonly used keywords are “refugees”, “syrian refugees,” “Syria,” “Turkey,” and “Lebanon.” Trend themes include “poverty”, “integration” and “health”. The country with the highest number of publications and references is Türkiye.",,,,,Syrian refugees; Refugee; Population; Library science; Web of science; Political science; Data science; Geography; Computer science; Sociology; Demography; MEDLINE; Law,,,,,https://dergipark.org.tr/tr/download/article-file/3938160 https://dergipark.org.tr/tr/pub/mejrs/issue/88718/1485879,http://dx.doi.org/10.70045/mejrs.1485879,,10.70045/mejrs.1485879,,,0,,0,true,,gold -116-899-725-415-655,Progress of Mine Land Reclamation and Ecological Restoration Research Based on Bibliometric Analysis,2023-07-03,2023,journal article,Sustainability,20711050,MDPI AG,Switzerland,Ya Shao; Qinxue Xu; Xi Wei,"The mining of mineral resources has caused serious damage to land and significant pressure on ecological environment. During the repairing of damaged land and degraded ecosystems, there have been many pieces of literature related to land reclamation and ecological restoration (LRER) that have emerged. To understand the progress and prospect of LRER research, it is necessary to sort out such pieces of literature, analyze the current research status, and forecast the future research directions. Here, Bibliometrix R-package was used to analyze 2357 articles, which were derived from the core database of Web of Science, to explore the development of LRER from 1990 to 2022. The results are as follows. (1) The annual scientific output results show that both the number of articles published on LRER and the number of articles annually citied were increasing gradually from 1990 to 2022. (2) High-frequency keyword analysis indicates that heavy metal (Cd, Pb) pollution remediation is a research hotspot. The cluster analysis (CA) and multiple correspondence analysis (MCA) show that there are two clusters in the current research of LRER, in which one surrounds heavy metal pollution and the other focuses on ecological restoration of mining areas. The two clusters correspond to the remediation and ecological restoration (rehabilitation) stages of stepwise ecological restoration, respectively. Thematic evolution analysis shows that, for more than 30 years, mine drainage and heavy metal pollution treatment, soil reconstruction (soil profile reconstruction, soil improvement), and vegetation restoration have been the focus of research. (3) Future research should focus on the relationship between mine ecological restoration and carbon sequestration and the relationship between ecological restoration and biodiversity in mine areas. In addition, LRER technology exchange, international cooperation, and industrialization are also main directions of development. Generally, in this study, metrology software (Bibliometrix R-package 3.1.4) from the literature was used to sort out the relevant literature on LRER over the past 30 years so as to provide reference for future research on LRER.",15,13,10458,10458,Land reclamation; Restoration ecology; Environmental remediation; Environmental science; Environmental resource management; Geography; Environmental planning; Ecology; Archaeology; Contamination; Biology,,,,the Project of National Natural Science Foundation of China; Guangxi Key Research and Development Program; Doctoral Research Foundation of Guilin University of Technology,https://www.mdpi.com/2071-1050/15/13/10458/pdf?version=1688373914 https://doi.org/10.3390/su151310458,http://dx.doi.org/10.3390/su151310458,,10.3390/su151310458,,,0,001-630-625-296-482; 001-719-026-803-199; 001-723-729-475-242; 003-192-969-136-808; 004-234-006-677-184; 004-278-162-272-714; 004-456-856-093-728; 005-450-682-083-00X; 009-893-359-417-098; 010-726-421-050-942; 011-942-619-161-018; 013-468-403-897-410; 013-507-404-965-47X; 014-749-700-483-377; 018-842-654-128-658; 019-134-892-684-990; 019-140-278-183-994; 022-659-678-038-656; 022-717-772-223-746; 023-051-550-256-997; 024-785-857-039-89X; 029-432-475-027-330; 030-036-965-584-35X; 032-120-716-832-492; 034-455-905-874-920; 034-918-049-650-323; 041-597-794-731-43X; 042-497-345-951-136; 044-807-726-552-685; 044-814-777-996-513; 044-925-896-237-183; 045-522-899-001-90X; 046-776-465-159-714; 047-614-329-214-541; 048-861-734-177-443; 050-760-437-593-220; 055-444-209-609-611; 057-923-231-261-077; 058-375-503-202-305; 059-059-159-196-39X; 065-065-010-314-886; 065-173-844-191-147; 065-816-345-312-721; 067-335-478-221-888; 067-403-507-858-493; 067-630-830-616-435; 068-330-230-058-638; 068-629-611-969-335; 069-732-192-451-460; 076-576-451-690-012; 077-353-955-876-038; 078-054-881-351-509; 079-028-878-871-930; 079-493-311-793-672; 080-984-751-989-849; 081-201-444-173-666; 087-208-414-091-408; 087-535-785-808-357; 087-709-381-313-312; 088-652-678-273-608; 089-910-503-281-767; 090-145-532-541-935; 090-315-859-165-07X; 092-413-186-992-354; 093-429-005-181-441; 095-490-410-831-781; 098-120-461-950-140; 098-258-940-429-215; 098-665-547-313-353; 100-397-399-446-200; 107-194-940-814-37X; 110-093-984-592-356; 113-891-348-463-065; 114-975-889-683-874; 118-450-449-660-250; 118-854-876-061-405; 121-301-758-881-46X; 121-410-062-583-387; 124-238-006-695-592; 125-566-178-898-694; 125-629-333-675-614; 126-480-011-648-14X; 131-043-494-630-82X; 131-701-491-500-466; 143-496-958-915-768; 152-597-780-752-488; 154-674-308-277-942; 156-434-878-684-451; 161-403-128-240-287; 164-887-511-042-163; 165-780-705-755-985; 168-295-349-507-300; 177-921-493-626-947; 186-672-252-653-41X,12,true,,gold -116-969-013-295-211,Trends and strategies in sustainable maritime transport: insights from global research,2024-07-15,2024,journal article,"Revista de Investigación, Desarrollo e Innovación",23899417; 20278306,Universidad Pedagogica y Tecnologica de Colombia (Hipertexto-Netizen),,Paola Marcela Alzate-Montoya; Valentina Giraldo-Ospina; Pedro Duque-Hurtado,"The green shipping faces ongoing challenges in meeting the demands of international trade with an environmental focus, driven by international regulations and negative impacts of the shipping industry on the environment. The purpose of this review is to examine research and strategies related to green shipping through a scientific mapping approach. Bibliometric tools such as R-Studio, Bibliometrix, ToS, and Gephi in graph theory were employed to represent the field's structure and trends. A total of 238 publications were selected from the Scopus database, covering the period between 2004 and 2023. The results highlight highly relevant themes, including optimizing maritime routes, adopting clean fuels, sustainable navigation policies, and modernizing the fleet of vessels. The strategic pillars to be implemented also emphasize the importance of business logistics, emission reduction, and increased productivity.",14,2,43,62,Business; Regional science; Environmental planning; Geography,,,,,,http://dx.doi.org/10.19053/uptc.20278306.v14.n2.2024.17922,,10.19053/uptc.20278306.v14.n2.2024.17922,,,0,001-825-800-134-975; 002-075-857-942-224; 002-559-107-034-869; 004-675-322-517-063; 006-248-661-023-494; 012-441-472-780-199; 012-873-050-211-673; 013-507-404-965-47X; 017-750-600-412-958; 018-649-993-978-468; 019-239-127-477-24X; 019-491-444-487-753; 020-083-376-142-640; 022-371-753-792-841; 023-423-595-259-010; 028-248-497-041-049; 028-951-479-542-557; 029-117-924-822-066; 035-776-087-538-274; 035-953-952-141-226; 037-351-422-912-518; 038-739-859-160-256; 040-148-545-247-997; 043-219-516-358-019; 043-829-557-493-178; 047-188-502-443-622; 048-405-665-460-202; 048-700-599-805-71X; 049-188-438-875-465; 051-308-389-838-056; 051-752-821-151-511; 052-343-570-104-137; 053-598-695-896-482; 054-373-079-205-886; 056-440-745-858-898; 057-137-754-758-674; 057-533-667-364-313; 057-803-697-074-453; 062-526-184-414-879; 063-702-758-111-911; 069-511-868-544-95X; 070-665-150-453-490; 071-048-222-720-571; 071-609-948-558-785; 072-630-581-032-439; 076-873-845-895-476; 077-446-102-740-449; 080-238-555-297-306; 080-382-614-196-422; 089-317-032-149-059; 091-823-156-047-699; 092-674-914-222-389; 093-186-636-893-601; 094-336-581-476-815; 096-474-214-374-276; 102-868-473-105-991; 104-761-573-060-244; 112-528-049-287-986; 114-715-395-543-475; 114-892-598-425-599; 122-255-014-590-776; 122-827-252-276-011; 136-093-293-636-317; 140-299-205-127-351; 141-953-343-806-408; 143-695-915-655-566; 143-936-693-364-687; 148-473-730-886-657; 151-336-483-768-908; 156-476-574-722-071; 157-855-842-243-277; 165-965-968-236-23X; 182-826-619-637-55X,0,true,cc-by,gold -117-231-024-447-343,"Supplementary Material - Overview of the global research on dung-inhabiting fungi: trends, gaps, and biases",2023-01-01,2023,dataset,Figshare,,,,Francisco Calaça; Jéssica Conceição Araújo; Carlos de Melo e Silva-Neto; Solange Xavier-Santos,"The file contains the supplementary data to Calaça et al's paper ""Overview of the global research on dung-inhabiting fungi: trends, gaps, and biases"", to the Current Research in Environmental & Applied Mycology (Journal of Fungal Biology). The spreadsheet named 'calaca_dung_fungi' is a database organized from data retrieved from the Web of Science and Scopus databases and merged and cleaned according to the criteria established in the manuscript using the different functions available in the bibliometrix package (Aria & Cuccurullo 2017) for the R environment. In this way, both fonts, style, and formatting of the database in data.dung.fungi, follow the necessary structure for uploading in the R environment using the code: install.packages(""bibliometrix"") + library(bibliometrix) + data <-read.csv(""~/desktop/calaca_database_dungfungi.csv"") + M <- convert2df(data, dbsource = ""wos"", format = ""csv"") + head(M[""TC""])",,,,,Ecology; Geography; Biology,,,,,https://figshare.com/articles/dataset/Supplementary_Material_-_Overview_of_the_global_research_on_dung-inhabiting_fungi_trends_gaps_and_biases/22300636/1,http://dx.doi.org/10.6084/m9.figshare.22300636.v1,,10.6084/m9.figshare.22300636.v1,,,0,,0,true,cc-by,gold -117-397-269-539-473,Bibliometric analysis of research on the utilization of nanotechnology in diabetes mellitus and its complications.,2024-07-02,2024,journal article,"Nanomedicine (London, England)",17486963; 17435889,Future Medicine Ltd.,United Kingdom,Jiexin Zhang; Meng He; Guanbin Gao; Taolei Sun,"Aim: To identify hotspots in this field and provide insights into future research directions. Methods: Publications were retrieved from the Web of Science Core Collection database. R Bibliometrix software, VOSviewer and CiteSpace were used to perform the bibliometric and visualization analyses. Results: The analysis comprised 468 publications from 58 countries, with the United States, China and India being the leading contributors. 'Gene therapy', 'nanoparticles' and 'insulin therapy' are the primary focuses. 'Green synthesis', 'cytotoxicity', 'bioavailability' and 'diabetic foot ulcers' have gained prominence, signifying high-intensity areas of interest expected to persist as favored research topics in the future. Conclusion: This study delves into recent frontiers and topical research directions and provides valuable references for further research in this field.",19,16,1449,1469,Diabetes mellitus; Medicine; Nanotechnology; Intensive care medicine; Internal medicine; Materials science; Endocrinology,bibliometrics; diabetes mellitus; green synthesis; insulin therapy; nanoparticles,Humans; Bibliometrics; Diabetes Mellitus/drug therapy; Nanotechnology/methods; Diabetes Complications; Nanoparticles; Genetic Therapy; Insulin; Nanomedicine/methods; Animals,Insulin,National Natural Science Foundation of China (Nos. 21975191 (GGB)),,http://dx.doi.org/10.1080/17435889.2024.2358741,39121376,10.1080/17435889.2024.2358741,,PMC11318711,0,000-595-185-222-393; 000-651-945-124-002; 002-137-774-543-667; 002-266-416-749-463; 003-085-985-465-480; 004-585-438-301-396; 004-781-788-236-385; 005-725-690-690-766; 006-060-647-284-351; 007-290-170-349-874; 007-491-086-162-979; 007-638-684-545-463; 008-225-183-326-79X; 008-289-950-532-811; 008-398-933-343-675; 009-630-020-860-002; 009-715-981-352-018; 010-640-831-367-902; 013-046-538-767-71X; 013-254-178-003-64X; 013-507-404-965-47X; 014-553-393-669-440; 016-427-040-469-238; 017-166-484-879-055; 017-800-000-615-172; 019-551-796-375-984; 024-936-454-888-526; 027-329-263-702-973; 028-344-021-381-734; 031-646-656-529-431; 034-396-308-243-154; 035-041-425-842-010; 035-054-616-520-842; 035-310-383-376-527; 035-689-318-694-00X; 035-754-768-715-718; 036-056-572-870-167; 037-800-682-554-279; 038-971-213-825-753; 041-588-342-904-868; 044-731-838-713-852; 044-748-870-049-104; 044-824-439-010-386; 044-923-258-528-008; 045-028-993-147-784; 051-435-660-437-033; 051-586-569-330-938; 052-624-380-270-397; 058-230-048-885-708; 060-207-446-271-484; 062-451-335-228-747; 064-742-240-131-558; 067-666-994-083-262; 067-732-244-573-871; 071-612-514-931-594; 074-627-731-607-679; 076-768-152-502-751; 077-821-994-748-842; 080-834-292-142-863; 084-586-020-832-233; 084-786-290-082-010; 085-374-722-362-514; 088-203-567-400-885; 088-869-517-030-370; 089-413-826-095-670; 090-207-220-621-021; 091-133-777-655-736; 091-349-875-013-502; 091-527-679-393-682; 093-084-922-294-135; 093-886-625-581-941; 094-398-599-092-493; 094-604-485-636-987; 094-740-547-097-007; 098-700-556-495-209; 099-679-791-862-18X; 101-442-477-383-951; 103-032-640-716-72X; 113-111-821-419-140; 113-728-924-635-524; 122-315-799-999-468; 124-473-721-925-991; 131-279-246-129-850; 144-877-500-867-165; 151-472-702-544-08X; 155-794-623-474-05X; 165-989-268-250-459; 173-193-475-257-430,2,false,, -117-790-080-671-13X,Bibliographic data and thesauraus files,2023-08-29,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Stephen Chignell; Terre Satterfield,Data for “Seeing beyond the frames we inherit: A challenge to tenacious conservation narratives” (published in People and Nature) Stephen M. Chignell and Terre Satterfield ------------------------------------------------------------------------------------------------------------------------------- This repository contains the following data files used in the above publication. Detailed information about how these data were collected and analyzed can be found at the journal website. Bibliographic data downloaded from Web of Science (raw text file format) Can be imported directly into bibliometrix/biblioshiny or VOSviewer software Bibliographic data downloaded from Web of Science (Microsoft Excel format) Can be imported directly into bibliometrix/biblioshiny software “Thesaurus” file created to disambiguate author names in VOSviewer software “Thesaurus” file created to disambiguate publication keywords in VOSviewer software “Thesaurus” file created to disambiguate author organizations in VOSviewer software,,,,,Computer science; Data file; Database; Information retrieval; World Wide Web,,,,,https://zenodo.org/record/8299593,http://dx.doi.org/10.5281/zenodo.8299593,,10.5281/zenodo.8299593,,,0,,0,true,cc-by,gold -118-094-640-391-61X,Hot spots and trends in microbial disease research on cultural heritage: a bibliometric analysis.,2024-05-14,2024,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Weilin Chen; Baorong Fu; Fang Ma; Zhe He; Ming Li,,31,24,35908,35926,Cultural heritage; Library science; Web of science; Geography; History; Archaeology; Political science; MEDLINE; Computer science; Law,Bibliometrics; Cultural heritage; Microbial diseases; R-bibliometrix; VOSviewer; Visual analysis,Humans; Bibliometrics; Culture; Infections,,"the State Key Laboratory Project of the State Key Laboratory of Urban Water Resources and Environment, Harbin Institute of Technology, China (ES201916)",,http://dx.doi.org/10.1007/s11356-024-33559-5,38743327,10.1007/s11356-024-33559-5,,,0,004-689-099-057-363; 004-837-295-747-531; 006-014-423-512-290; 008-234-297-177-547; 008-866-848-834-837; 012-194-620-035-495; 015-077-696-742-088; 016-021-183-089-662; 016-457-138-646-324; 020-003-713-361-375; 020-329-122-176-813; 021-914-894-124-486; 025-701-770-453-663; 026-273-456-891-639; 032-365-510-810-648; 032-689-469-436-711; 033-268-204-903-290; 035-479-579-308-685; 038-441-595-290-660; 040-806-995-853-419; 046-162-520-923-361; 046-399-319-786-356; 050-125-218-631-546; 051-087-462-574-178; 052-563-137-922-731; 053-788-498-120-201; 054-344-254-556-083; 056-192-091-373-153; 057-660-166-044-217; 061-855-563-475-859; 062-535-989-344-075; 065-242-735-048-532; 070-473-451-875-48X; 071-139-477-375-451; 072-167-888-156-127; 078-547-062-290-779; 078-945-858-004-081; 080-059-773-160-435; 092-024-544-532-747; 094-367-221-468-08X; 101-689-564-718-291; 107-048-826-996-725; 108-029-148-709-59X; 119-364-319-375-81X; 119-401-794-937-324; 126-202-436-743-409; 127-313-514-485-512; 129-825-212-316-803; 130-435-171-263-224; 135-854-218-082-147; 145-108-884-422-869; 150-992-340-813-82X; 152-575-239-973-55X; 155-047-709-258-447; 167-545-129-227-350; 175-757-260-369-666; 179-712-162-258-248,1,false,, -118-357-176-517-195,thesaurus-bib-replace.txt,2023-01-01,2023,dataset,Figshare,,,,Gaimei She,"""thesaurus-bib-replace.txt"": Duplicate keywords merged file applied in Bibliometrix software. VOSviewer v1.6.18.0 and Bibliometricx were used to perform the analyses of the collected documents. This file was used in Bibliometricx software.",,,,,Thesaurus; Information retrieval; Computer science; Natural language processing,,,,,https://figshare.com/articles/dataset/thesaurus-bib-replace_txt/21875340,http://dx.doi.org/10.6084/m9.figshare.21875340,,10.6084/m9.figshare.21875340,,,0,,0,true,cc-by,gold -118-462-575-359-619,Circular Economy in the Cement Industry: a Systematic Review of Sustainability Assessment and Justice Considerations in Local Community Development,2025-06-04,2025,journal article,Circular Economy and Sustainability,2730597x; 27305988,Springer Science and Business Media LLC,,Susan K. Onsongo; John Olukuru; Onesmus Mwabonje,"Abstract; The cement industry contributes significantly to local economies by creating jobs and supporting industries such as healthcare, education and transportation. While cement contributes to development and economic growth, it also poses serious risks to the natural environment and human health. A systematic literature review based on a bibliometric analysis was conducted. The search focused on studies related to the cement and construction industries, circular economy, sustainability approaches, and impacts of cement and concrete. A refined key word search was used to select articles from the Scopus database. This resulted in a final selection of 197 documents that fit the inclusion criteria. While most of the circular economy research studies reviewed offered technical solutions such as optimizing efficient production processes or recycling materials, there were fewer studies that examined the socio-economic and governance dimensions of circular economy practices, hence the knowledge gap. To supplement this, case studies from cement companies globally were reviewed to provide practical solutions that can facilitate the transition to circular economy practices while ensuring social justice considerations for local communities. Reviewed studies found a positive association between presence of cement plants and economic growth of local communities but negative associations between exposure to cement plants, the natural environment and human health. This review highlights the significant need to integrate socio-economic and environmental dimensions into sustainability efforts and inform policymakers about these impacts to develop long-term sustainable practices. Achieving this balance is critical to maximizing benefits and minimizing harm in local communities affected by cement production.",,,,,,,,,,,http://dx.doi.org/10.1007/s43615-025-00606-3,,10.1007/s43615-025-00606-3,,,0,001-042-196-746-893; 002-477-756-430-811; 002-540-922-858-645; 004-263-538-553-222; 005-963-117-554-490; 006-694-721-991-762; 007-509-914-757-082; 009-573-600-591-613; 010-184-556-241-697; 012-011-156-435-772; 013-196-577-416-027; 013-500-341-713-889; 013-507-404-965-47X; 013-659-177-897-86X; 015-832-818-958-095; 018-720-226-211-724; 023-005-161-227-685; 023-190-829-454-448; 024-072-364-739-812; 024-570-636-174-643; 025-167-933-061-81X; 025-589-697-604-99X; 026-470-922-646-765; 026-779-469-943-555; 028-410-478-863-146; 029-542-051-797-929; 030-816-585-695-960; 031-254-702-149-059; 032-144-161-606-032; 033-222-886-929-557; 036-735-075-887-931; 038-260-224-496-501; 041-183-957-721-659; 043-671-667-921-084; 044-651-244-230-749; 046-217-412-051-127; 048-128-294-408-559; 049-453-987-158-877; 051-500-464-097-578; 052-407-977-495-635; 053-810-111-485-678; 056-987-396-536-24X; 059-394-248-571-276; 061-818-193-542-192; 063-316-658-760-249; 064-120-241-480-139; 067-052-817-940-917; 073-607-933-576-730; 074-008-626-267-526; 079-187-950-544-060; 083-137-544-456-89X; 091-228-136-960-580; 092-037-271-061-638; 092-279-964-963-855; 095-686-520-125-655; 097-038-251-988-790; 097-330-094-590-049; 101-462-284-314-579; 103-438-380-458-161; 106-021-372-662-395; 109-294-951-435-325; 113-751-599-073-198; 117-081-135-405-946; 125-907-414-142-518; 128-271-806-034-792; 129-007-835-453-009; 129-134-075-645-009; 129-147-249-063-133; 129-615-714-286-995; 131-474-448-885-877; 138-246-010-653-57X; 160-252-863-529-536; 162-962-140-481-160; 168-025-419-738-009; 171-560-398-946-898; 173-104-037-102-669; 188-685-760-450-147; 191-769-710-149-74X,0,true,cc-by,hybrid -118-520-099-000-850,A Science Mapping of Cultural Intelligence (CQ) Research,,2022,journal article,Academy of Management Proceedings,00650668; 21516561; 23767197,Academy of Management,,Andrea Caputo; Mariya Kargina,"This paper presents the science map of the research produced around cultural intelligence (CQ) from management scholars. To systematize knowledge about CQ, a bibliometric analysis of 513 articles retrieved from the Web of Science Core Collection database has been made via the bibliometrix package in R, covering a range of studies from 2002 until 2020. The analyses present results concerning the performance of CQ research published in scientific journals, the geography of CQ research, and the identification of the main articles and thematic areas of research. Future research directions are drawn from the state of the art of cultural intelligence research.",2022,1,,,Identification (biology); Thematic map; Web of science; Data science; Cultural intelligence; Computer science; Library science; Geography; Psychology; Cartography; MEDLINE; Political science; Biology; Social psychology; Botany; Law,,,,,https://figshare.com/articles/conference_contribution/A_Science_Mapping_of_Cultural_Intelligence_CQ_Research/25179842/1/files/44459609.pdf https://figshare.com/articles/conference_contribution/A_Science_Mapping_of_Cultural_Intelligence_CQ_Research/25179842,http://dx.doi.org/10.5465/ambpp.2022.12863abstract,,10.5465/ambpp.2022.12863abstract,,,0,,0,true,,green -118-723-856-382-56X,Coating of corn seeds: scientific advances and global collaborations towards agricultural sustainability,2025-03-31,2025,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Lailson César Andrade Gomes; João Luciano de Andrade Melo Júnior; Luan Danilo Ferreira de Andrade Melo; Ana Paula do Nascimento Prata Lins,"Seed coatings play a critical role in modern agriculture by incorporating protectants, fertilizers and beneficial microorganisms to enhance germination, plant establishment and resistance to biotic and abiotic stresses. In recent years, scientific interest in these technologies has increased, driven by the need for more efficient and sustainable production systems. However, gaps remain in understanding key research trends, leading authors, and international collaborations in the field. This study aimed to conduct a detailed bibliometric analysis of the scientific production on corn seed coating to identify research trends, collaborative networks, and scientific impact. A total of 239 articles from the Web of Science and Scopus databases were analyzed, revealing significant growth in publications, particularly in China, the USA and Brazil. Key topics include biological control, seed treatment efficacy, and environmental impact mitigation, reflecting the balance between productivity and agricultural sustainability. The analysis identified the most influential authors, institutions and journals, with Crop Protection and Pest Management Science playing a central role. A strong international collaborative network was also observed, with countries such as Canada and Denmark showing high relevance and citation impact despite lower publication volumes. Future trends point to the development of coatings that integrate biological control agents and controlled-release nutrient technologies to promote environmentally friendly agricultural practices. This study provides a strategic perspective to guide scientific advances and influence global policy toward sustainable maize production.",6,1,,,Sustainability; Agriculture; Coating; Business; Agricultural economics; Agricultural engineering; Natural resource economics; Engineering; Economics; Nanotechnology; Materials science; Geography; Biology; Ecology; Archaeology,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,,http://dx.doi.org/10.1007/s43621-025-01067-2,,10.1007/s43621-025-01067-2,,,0,000-006-849-543-571; 000-854-814-606-183; 004-605-113-723-748; 011-755-048-715-668; 013-507-404-965-47X; 019-128-299-119-244; 019-840-919-954-056; 020-990-850-359-302; 024-534-437-503-602; 028-724-710-620-31X; 030-125-542-603-904; 034-247-094-749-168; 034-400-627-249-771; 037-891-239-946-83X; 040-931-585-258-644; 046-266-889-121-736; 050-034-635-874-430; 051-827-394-947-50X; 052-303-321-160-561; 060-067-465-867-150; 060-706-033-193-074; 060-841-243-742-969; 065-472-476-235-256; 066-158-891-913-967; 070-255-245-050-107; 070-796-863-096-315; 071-419-678-266-389; 074-274-085-368-667; 089-459-296-312-837; 090-460-730-055-655; 097-974-677-819-099; 104-056-638-993-122; 123-581-025-798-345; 154-219-349-387-334; 157-690-506-616-991; 157-875-284-555-599; 160-339-201-764-571; 178-044-387-793-535; 193-752-699-894-037,0,true,cc-by,gold -118-758-914-104-016,ICT-Based Research Tools to Determine the Importance of Vaccine Distribution in Supply Chain Efficiency: Specific Case of Bibliometrix,2022-11-01,2022,book chapter,Lecture Notes in Networks and Systems,23673370; 23673389,Springer Nature Singapore,,Sufian Qrunfleh; Shiri Vivek; Russ Merz,,,,199,206,Supply chain; Resilience (materials science); Information and Communications Technology; Field (mathematics); Distribution (mathematics); Business; Computer science; Marketing; Mathematics; Mathematical analysis; Physics; World Wide Web; Pure mathematics; Thermodynamics,,,,,,http://dx.doi.org/10.1007/978-981-19-5221-0_20,,10.1007/978-981-19-5221-0_20,,,0,005-929-467-959-843; 013-507-404-965-47X; 032-957-151-912-51X; 037-159-723-803-497; 045-646-816-754-24X; 065-765-542-730-896; 073-292-982-037-625; 079-132-199-997-240; 091-848-577-995-962,1,false,, -118-800-948-785-16X,Економісти України: Хто Вони Такі І Де Вони Публікуються?,,2018,,,,,,Максим Обрізан,"В рамках цієї наукової роботи проведено аналіз 1672 англомовних статей, опублікованих українськими економістами протягом 1991-2017 рр., з використанням бази даних SCOPUS та інструменту Bibliometrix у мові R. Між 2011 та 2012 роками, кількість опублікованих робіт збільшилася більш ніж у десять разів завдяки журналам «Актуальні проблеми економіки» (Actual Problems of Economics) та «Економічний часопис-ХХІ» (Economic Annals-XXI), які є найважливішими інформаційними джерелами, що опублікували більше 70 відсотків усіх статей. Незважаючи на покращення впізнаваності, індекс цитувань свідчить про досить скромний внесок українських економістів. Регресійний аналіз цитувань вказує на те, що статті з іноземним співавтором та ідентифікатором цифрового об'єкта частіше отримують цитування.",1,1,2,11,,,,,,https://ideas.repec.org/a/kse/chasop/v1y2018i1p3-12.html,https://ideas.repec.org/a/kse/chasop/v1y2018i1p3-12.html,,,2889970450,,0,,0,false,, -119-000-549-914-412,bibliometrix: Comprehensive Science Mapping Analysis,2016-05-08,2016,dataset,CRAN: Contributed Packages,,The R Foundation,,Massimo Aria; Corrado Cuccurullo,,,,,,Data science; Computer science; Geography,,,,,,http://dx.doi.org/10.32614/cran.package.bibliometrix,,10.32614/cran.package.bibliometrix,,,0,013-507-404-965-47X,10,false,, -119-400-156-378-99X,Lost in definition: unravelling microplastics from marine coatings through bibliometrics science mapping in thematic analysis and systematic narrative literature review,2025-03-08,2025,journal article,Environmental Sciences Europe,21904715; 21904707,Springer Science and Business Media LLC,Germany,Gina Kum; Olof Berglund; Johan Hollander,"Abstract; Marine coatings used on merchant ships have recently emerged as a source of microplastics in marine environments. Marine coatings encompass all paints and coatings applied to various parts of a ship, primarily for anti-corrosion, antifouling anti-skid, heat-resistance, and cosmetic enhancement. However, marine coatings on merchant ships have evaded classification and were not included in the microplastic literature until recently. The purpose of this study is to examine the current state of the absence of a unified definition on a global scale, identify the factors that contribute to the exclusion of marine coatings under the microplastic classification and to analyse the thematic mapping and evolution of the keywords “definition”, “classification”, and “paint” or “marine coatings” in the field of microplastics. We conducted science mapping analysis using Bibliometrix software to examine 1078 papers and carried out a systematic narrative literature review to examine the current state of a standardised definition of microplastics and whether the absence of such impedes a unified interpretation and study of microplastics from marine coatings. Based on the science mapping analysis, this research indicates that “definition” and “paint” have become important keywords in the domain of microplastic research lately, playing a vital role in structuring the field. Meanwhile, the systematic narrative literature review unveiled that the absence of a standardised definition remains a subject of considerable debate, resulting in marine coatings evading classification as microplastics. With this study, we aim to advocate for the establishment of more precise guidelines and policies pertaining to microplastic pollution in marine environments and to promote the adoption of a unified approach towards the definition and classification of microplastics for the purposes of legislation and research. This will also path the way for the collection of better data on microplastic emissions from marine coatings, thereby closing the knowledge gap in this area.",37,1,,,Microplastics; Bibliometrics; Thematic map; Narrative; Thematic analysis; Sociology; Ecology; Geography; Library science; Biology; Social science; Computer science; Art; Literature; Qualitative research; Cartography,,,,Hempel; Lund University,,http://dx.doi.org/10.1186/s12302-025-01070-4,,10.1186/s12302-025-01070-4,,,0,000-479-877-471-691; 001-063-951-728-06X; 003-764-367-709-198; 004-819-527-814-707; 006-338-770-720-909; 008-864-188-149-025; 012-349-244-069-483; 013-507-404-965-47X; 016-235-154-360-824; 016-988-328-955-710; 017-225-601-087-258; 018-082-310-164-058; 018-878-509-274-16X; 021-382-797-777-739; 021-512-710-737-412; 021-640-809-196-392; 022-489-331-558-856; 029-929-986-330-925; 031-219-778-784-629; 034-184-111-767-814; 041-295-929-249-728; 041-608-784-949-815; 046-477-814-791-110; 048-053-349-235-55X; 050-354-105-666-389; 051-647-739-244-271; 055-862-112-478-450; 060-737-246-484-010; 063-274-593-368-787; 065-010-405-236-060; 065-345-226-917-199; 070-826-212-118-108; 071-984-058-908-266; 072-605-998-942-513; 074-395-715-889-469; 074-791-690-026-513; 075-613-527-677-935; 077-630-549-498-10X; 077-726-503-422-747; 082-872-348-505-206; 095-436-961-336-050; 096-994-878-218-857; 100-673-233-274-267; 116-737-817-825-895; 131-752-157-895-060; 147-286-975-643-813; 165-077-830-370-836; 169-027-103-121-278,1,true,cc-by,gold -119-427-694-294-953,A note on reference publication year spectroscopy with incomplete information,2021-04-26,2021,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Matthieu Ballandonne; Igor Cersosimo,,126,6,4927,4939,Complete information; Information retrieval; Zero (linguistics); Simulated data; Field (computer science); Smoothing; Computer science; Scientometrics,,,,,https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics126.html#BallandonneC21 https://link.springer.com/article/10.1007/s11192-021-03976-1 https://doi.org/10.1007/s11192-021-03976-1,http://dx.doi.org/10.1007/s11192-021-03976-1,,10.1007/s11192-021-03976-1,3157321074,,0,001-649-830-409-124; 004-559-378-182-161; 011-088-825-646-470; 012-929-204-380-980; 013-507-404-965-47X; 014-068-213-874-326; 035-431-036-005-052; 038-284-034-161-109; 040-969-805-240-336; 057-035-349-769-196; 071-092-418-193-978; 086-409-842-893-209; 089-278-009-945-752; 108-548-693-867-467; 117-297-168-926-994; 134-891-406-896-339; 147-199-278-864-535; 150-325-162-873-23X; 161-209-590-737-139; 167-148-923-567-724; 169-068-496-045-683; 185-387-562-261-666,9,false,, -119-994-438-577-170,Global Research Trends and Hotspots in Fracture Nonunion and Delayed Union: A 2-Decade Bibliometric Analysis,2025-05-14,2025,journal article,Indian Journal of Orthopaedics,00195413; 19983727,Springer Science and Business Media LLC,India,Shaole Wan; Yonghui Shen; Sen Cai; Zengyong Hu; Fangru Ouyang; Lingtao Xu,,,,,,Medicine; Nonunion; Delayed union; Surgery,,,,,,http://dx.doi.org/10.1007/s43465-025-01410-9,,10.1007/s43465-025-01410-9,,,0,000-914-780-831-80X; 003-038-266-341-578; 003-756-213-857-745; 004-470-013-795-343; 007-934-032-417-155; 009-348-370-770-702; 010-861-006-629-617; 011-735-809-072-364; 014-239-918-576-63X; 015-681-279-751-662; 018-750-583-801-762; 020-133-536-291-243; 020-581-013-628-133; 022-100-441-794-00X; 026-249-961-451-925; 028-404-621-106-797; 029-777-623-081-632; 030-634-627-402-277; 037-183-618-460-699; 037-727-540-843-595; 038-706-004-669-769; 039-841-570-973-886; 041-261-902-941-970; 043-182-259-047-976; 045-671-603-063-693; 047-611-394-039-58X; 048-225-729-449-97X; 048-747-213-586-365; 049-819-003-424-743; 050-355-861-743-495; 050-753-222-029-512; 050-999-034-319-088; 053-755-842-344-546; 055-710-262-743-560; 059-754-812-264-143; 061-941-269-619-12X; 062-732-771-133-85X; 063-016-379-067-746; 064-668-713-786-018; 068-371-633-724-376; 071-319-063-876-959; 071-601-203-388-746; 074-881-003-088-325; 076-872-388-536-173; 077-191-660-919-679; 077-534-362-673-289; 085-500-214-455-188; 089-341-014-457-779; 093-185-007-036-784; 094-329-677-831-29X; 096-995-981-315-975; 099-603-934-855-403; 100-317-116-827-298; 102-082-828-108-637; 109-083-396-399-897; 109-686-899-676-756; 111-106-612-502-360; 113-275-849-071-634; 114-105-968-711-889; 117-291-534-783-296; 125-608-443-538-482; 128-858-492-760-355; 129-839-739-458-688; 136-529-013-943-924; 144-204-324-853-955; 148-927-543-368-938; 150-654-911-108-234; 153-108-877-433-279; 153-687-836-522-362; 158-371-960-541-692; 158-833-094-545-630; 161-166-310-018-344,0,false,, -120-013-143-055-767,Enhanced recovery after surgery from 1997 to 2022: a bibliometric and visual analysis.,2024-03-06,2024,journal article,Updates in surgery,20383312; 2038131x,Springer Science and Business Media LLC,Germany,Jingyu Dong; Yuqiong Lei; Yantong Wan; Peng Dong; Yingbin Wang; Kexuan Liu; Xiyang Zhang,,76,4,1131,1150,Bibliometrics; Medicine; Prehabilitation; Perioperative; Web of science; MEDLINE; General surgery; Surgery; Library science; Meta-analysis; Computer science; Physical therapy; Internal medicine; Political science; Law,Bibliometric; CiteSpace; Enhanced recovery after surgery; VOSviewer; Visual analysis,Bibliometrics; Humans; Enhanced Recovery After Surgery,,,,http://dx.doi.org/10.1007/s13304-024-01764-z,38446378,10.1007/s13304-024-01764-z,,,0,002-052-422-936-00X; 002-512-359-427-599; 003-621-941-565-953; 004-221-136-998-936; 005-620-383-996-713; 005-735-767-417-784; 006-985-113-050-491; 007-331-695-564-145; 008-546-383-425-773; 008-654-241-543-019; 008-743-726-206-242; 009-126-568-174-072; 009-265-975-831-72X; 011-789-499-048-134; 012-491-459-342-915; 013-507-404-965-47X; 016-079-774-941-222; 020-762-932-546-078; 021-490-974-048-94X; 022-686-298-469-159; 026-198-393-257-907; 026-395-112-558-483; 026-449-309-039-434; 029-866-927-836-058; 031-194-242-215-42X; 031-650-549-118-313; 032-254-035-949-568; 035-138-687-231-624; 035-657-428-047-94X; 035-710-747-566-122; 040-872-517-722-452; 041-158-214-327-55X; 043-259-528-590-68X; 043-416-836-313-023; 044-055-638-459-043; 045-563-094-292-878; 045-667-177-094-080; 046-671-709-034-838; 047-374-963-704-61X; 049-220-378-260-844; 049-825-174-362-373; 056-338-592-881-462; 056-879-630-803-126; 058-870-407-782-504; 061-966-587-718-925; 063-053-087-817-640; 066-015-512-389-037; 067-106-329-865-349; 068-402-021-138-199; 071-460-574-277-256; 071-985-543-971-79X; 076-176-373-466-441; 077-961-924-415-246; 083-085-024-863-211; 086-900-874-533-320; 095-125-539-764-043; 095-432-010-680-720; 095-609-071-962-028; 096-602-393-806-524; 103-018-019-813-774; 103-418-202-709-88X; 106-612-884-530-833; 107-699-076-103-471; 115-050-470-073-34X; 119-656-280-785-444; 121-808-848-245-080; 122-254-501-985-316; 136-958-636-434-11X; 137-632-303-996-364; 141-867-143-032-566; 152-540-160-108-555; 167-342-694-448-13X; 172-564-627-690-211; 184-908-374-156-003; 187-102-874-311-125; 188-656-141-847-695,5,false,, -120-233-400-217-697,Collision of herbal medicine and nanotechnology: a bibliometric analysis of herbal nanoparticles from 2004 to 2023.,2024-04-01,2024,journal article,Journal of nanobiotechnology,14773155,Springer Science and Business Media LLC,United Kingdom,Sinan Ai; Yake Li; Huijuan Zheng; Meiling Zhang; Jiayin Tao; Weijing Liu; Liang Peng; Zhen Wang; Yaoxian Wang,"Herbal nanoparticles are made from natural herbs/medicinal plants, their extracts, or a combination with other nanoparticle carriers. Compared to traditional herbs, herbal nanoparticles lead to improved bioavailability, enhanced stability, and reduced toxicity. Previous research indicates that herbal medicine nanomaterials are rapidly advancing and making significant progress; however, bibliometric analysis and knowledge mapping for herbal nanoparticles are currently lacking. We performed a bibliometric analysis by retrieving publications related to herbal nanoparticles from the Web of Science Core Collection (WoSCC) database spanning from 2004 to 2023. Data processing was performed using the R package Bibliometrix, VOSviewers, and CiteSpace.; In total, 1876 articles related to herbal nanoparticles were identified, originating from various countries, with China being the primary contributing country. The number of publications in this field increases annually. Beijing University of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, and Saveetha University in India are prominent research institutions in this domain. The Journal ""International Journal of Nanomedicine"" has the highest number of publications. The number of authors of these publications reached 8234, with Yan Zhao, Yue Zhang, and Huihua Qu being the most prolific authors and Yan Zhao being the most frequently cited author. ""Traditional Chinese medicine,"" ""drug delivery,"" and ""green synthesis"" are the main research focal points. Themes such as ""green synthesis,"" ""curcumin,"" ""wound healing,"" ""drug delivery,"" and ""carbon dots"" may represent emerging research areas.; Our study findings assist in identifying the latest research frontiers and hot topics, providing valuable references for scholars investigating the role of nanotechnology in herbal medicine.; © 2024. The Author(s).",22,1,140,,Web of science; Traditional medicine; Nanomedicine; Bibliometrics; Curcumin; Alternative medicine; Medicine; Nanotechnology; Nanoparticle; Pharmacology; Chemistry; Library science; MEDLINE; Computer science; Materials science; Biochemistry; Pathology,Bibliometric analysis; Citespace; Herbal medicine; Herbal nanoparticles; Nanoparticles; Traditional Chinese medicine; VOSviewer,"Humans; Plants, Medicinal; China; Nanoparticles; Bibliometrics; Plant Extracts",Plant Extracts,National Natural Science Foundation of China (82004272); National Natural Science Foundation of China (82170817); National Natural Science Foundation of China (82274460); National Natural Science Foundation of China (82174342); Beijing Municipal Natural Science Foundation of China (7222160); National High Level Hospital Clinical Research Funding (2023-NHLHCRF-DJZD-01); Beijing Research Ward Construction Clinical Research (2022-YJXBF-04-02),https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-024-02426-3 https://doi.org/10.1186/s12951-024-02426-3,http://dx.doi.org/10.1186/s12951-024-02426-3,38556857,10.1186/s12951-024-02426-3,,PMC10983666,0,000-842-379-173-847; 000-882-881-825-085; 001-155-125-234-293; 001-247-967-752-52X; 001-290-346-890-114; 001-783-867-194-558; 002-208-679-880-230; 002-337-086-072-773; 002-495-533-514-339; 002-664-999-840-739; 003-534-216-345-899; 003-568-475-958-177; 003-847-352-938-899; 004-545-104-662-320; 004-963-872-820-864; 005-470-266-999-711; 007-305-298-643-625; 007-662-675-046-179; 009-157-199-676-529; 010-018-558-311-544; 011-143-545-898-082; 012-272-229-877-842; 013-507-404-965-47X; 013-516-242-142-626; 014-697-769-706-645; 015-254-051-111-910; 015-745-110-875-782; 015-933-893-413-469; 016-452-722-222-27X; 016-695-896-238-526; 018-255-425-507-033; 019-389-492-131-611; 020-223-686-771-663; 021-837-844-028-019; 022-331-160-003-038; 022-403-298-469-893; 023-454-745-609-664; 023-564-967-341-015; 025-277-947-572-458; 025-974-488-162-399; 026-608-004-263-844; 027-439-710-000-437; 028-227-248-943-022; 028-398-638-868-220; 028-404-621-106-797; 029-812-035-740-444; 030-006-698-151-690; 030-452-100-717-451; 031-112-911-330-184; 032-246-218-148-755; 032-339-162-142-583; 032-882-981-469-808; 032-960-185-747-353; 033-895-570-262-203; 034-184-887-119-937; 035-565-471-742-931; 035-955-420-947-447; 036-913-621-680-479; 038-019-405-034-41X; 039-094-935-584-175; 039-150-877-540-230; 039-827-984-746-455; 039-901-614-396-278; 040-440-644-546-472; 041-176-013-994-347; 041-447-754-392-847; 041-875-002-817-727; 043-247-272-519-629; 043-504-105-702-420; 044-551-775-253-079; 044-662-585-088-350; 044-897-505-818-998; 045-931-583-664-157; 046-542-991-439-589; 046-628-268-730-569; 047-501-443-838-381; 047-772-358-255-83X; 048-933-169-966-246; 049-759-697-003-502; 050-248-942-108-166; 051-063-591-155-74X; 054-215-509-912-529; 054-506-133-186-142; 055-117-573-731-818; 055-220-285-789-404; 056-295-208-299-201; 057-138-459-435-121; 057-145-863-032-071; 057-901-817-770-875; 058-060-752-775-853; 061-468-542-000-651; 061-587-373-196-105; 063-507-654-101-205; 064-469-174-048-953; 066-689-450-364-467; 068-537-665-367-788; 068-708-330-848-313; 068-723-058-200-803; 069-261-086-021-469; 070-336-596-969-929; 070-438-112-109-357; 070-564-405-155-848; 070-967-606-794-335; 074-311-162-430-584; 074-328-074-653-455; 074-925-692-970-533; 076-448-616-640-093; 077-770-694-901-393; 077-853-909-240-195; 079-693-308-554-634; 079-899-864-879-011; 081-954-116-700-419; 082-109-333-555-404; 085-542-938-096-307; 085-774-478-648-547; 086-384-003-848-257; 088-443-883-036-15X; 090-476-872-676-699; 091-283-664-251-632; 091-877-275-707-163; 092-439-902-505-912; 092-485-896-256-59X; 092-564-857-794-323; 094-553-882-540-789; 095-367-230-740-264; 097-636-548-920-13X; 097-733-021-423-094; 097-895-873-789-039; 098-966-585-322-364; 099-154-933-664-735; 099-782-970-670-496; 099-886-976-259-899; 100-466-426-171-078; 101-752-490-869-458; 101-826-643-324-555; 104-053-324-418-981; 104-193-914-892-223; 104-225-901-806-430; 104-812-145-133-635; 104-912-978-424-849; 111-817-322-378-382; 112-564-603-595-977; 115-089-280-562-394; 115-573-840-196-201; 116-464-967-868-419; 117-329-850-887-207; 120-719-929-958-022; 121-676-713-930-599; 121-902-341-748-931; 123-537-620-533-917; 124-835-708-619-354; 127-733-515-526-284; 128-472-554-100-992; 130-403-865-005-426; 136-088-521-399-936; 138-211-942-615-581; 138-307-479-651-893; 141-425-889-983-642; 141-672-015-138-219; 141-770-516-078-794; 145-902-450-761-984; 146-549-356-022-60X; 147-803-085-179-193; 148-701-904-116-401; 155-769-438-746-071; 158-985-914-224-086; 160-964-519-852-372; 165-059-043-158-394; 165-752-709-146-150; 167-284-903-605-849; 167-373-519-239-682; 171-082-672-068-722; 174-014-822-820-989; 178-832-384-981-52X; 180-505-030-446-267; 181-757-215-932-138; 181-845-072-329-672; 182-546-357-043-957; 189-150-172-024-841; 190-266-453-559-826; 190-755-516-522-375; 191-695-662-165-577; 196-672-049-901-871; 198-123-839-918-134,17,true,"CC BY, CC0",gold -120-275-559-981-609,Analysis of convergence between a unified One Health policy framework and imbalanced research portfolio,2024-07-30,2024,journal article,Discover Public Health,30050774,Springer Science and Business Media LLC,,Lisa Vors; Didier Raboisson; Guillaume Lhermie,"AbstractThe One Health (OH) approach is collaborative, multisectoral, and transdisciplinary, acknowledging the interdependence among animal, human and environmental health. It has garnered attention within the scientific community, particularly in response to the rising prevalence and global spread of emerging and re-emerging infectious diseases. Common OH issues include zoonotic diseases, antimicrobial resistance (AMR), food and water safety, and the human-animal bond. Among various OH topics, AMR represents a well-described, long-term, complex issue, with a substantial global death toll and large economic costs. Whereas interdisciplinary and transdisciplinary teamwork seems appropriate to address such complex challenges, effects on knowledge production are poorly known. In this study, we investigate how the scientific community mobilizes “One Health.” A comparative bibliometric analysis of OH and AMR research enabled us to assess the level of transdisciplinary research, identify emerging themes, through a co-occurrence network analysis of keywords, and disciplines mobilized, through a co-citation network analysis of scientific journals, in research, as well as level of international collaboration through analysis of co-authorship among countries. We detected a lack of consideration for non-communicable diseases (e.g., obesity, diabetes, cardiovascular diseases) and the well-being of human and animal populations in analysis of themes. Furthermore, although many disciplines are involved in OH and AMR research, little attention was given to social sciences, environmental health, economics, and politics. There was a strong influence of major global economic powers, including the United States and China, in scientific research on OH and AMR, as well as substantial collaboration among European countries. The present results indicated that guidelines are needed to address the mentioned concerns, and specific funds are required for underrepresented countries.",21,1,,,Political science; One Health; Global health; Portfolio; Public health; Medicine; Business; Health care; Nursing; Finance; Law,,,,,https://link.springer.com/content/pdf/10.1186/s12982-024-00159-0.pdf https://doi.org/10.1186/s12982-024-00159-0,http://dx.doi.org/10.1186/s12982-024-00159-0,,10.1186/s12982-024-00159-0,,,0,000-627-564-186-760; 000-667-231-896-402; 002-052-422-936-00X; 003-439-475-855-660; 008-014-346-698-775; 008-260-639-672-919; 013-271-122-944-293; 013-507-404-965-47X; 014-471-974-577-297; 017-056-077-624-568; 023-930-634-851-081; 025-302-119-966-613; 030-070-985-228-781; 038-531-119-181-198; 039-239-735-814-84X; 042-118-672-628-739; 044-046-699-358-815; 044-301-465-178-737; 045-422-273-148-899; 046-992-864-415-70X; 049-341-834-389-571; 054-060-313-651-79X; 064-412-026-419-380; 064-522-152-426-642; 068-249-492-835-339; 068-275-197-123-151; 068-801-058-088-218; 079-565-233-262-541; 081-956-575-294-885; 082-820-409-837-534; 088-455-388-401-875; 103-949-813-794-780; 105-569-140-121-271; 113-571-170-346-466; 114-756-990-576-950; 132-822-350-322-085; 133-473-647-054-580; 137-728-926-761-947; 139-618-682-036-014; 142-426-526-834-382; 158-325-166-960-93X; 160-617-423-122-969; 166-255-448-727-131; 172-627-306-127-175; 188-217-968-680-366; 192-227-245-814-459,0,true,"CC BY, CC BY-NC-ND",gold -120-785-684-616-096,Reshoring: A review and research agenda,,2023,journal article,Journal of Business Research,01482963; 18737978,Elsevier BV,Netherlands,Daniel Pedroletti; Francesco Ciabuschi,"In the last years, research on reshoring has gained momentum and experienced rapid development. Relying on bibliometric and content analyses of 135 articles from the Web of Science and Scopus databases, this review takes stock and guides future research on the topic. In particular, performing bibliometric performance analysis, conceptual thematic mapping and bibliographic coupling using the Bibliometrix R-package, this study identifies the main contributions to reshoring research, its conceptual structure and emerging themes. Combining the results of bibliometric and content analyses, we propose a conceptual reshoring framework characterized by five main themes: (i) antecedents, (ii) contingencies, (iii) decision, (iv) implementation, and (v) outcome. Following this framework, we organize and discuss past literature, propose a research agenda for each single theme and new avenues for future research on the conceptualization of reshoring as a process.",164,,114005,114005,Conceptualization; Conceptual framework; Scopus; Thematic analysis; Knowledge management; Bibliographic coupling; Content analysis; Management science; Sociology; Data science; Computer science; Qualitative research; Political science; Social science; Engineering; Library science; Citation; MEDLINE; Artificial intelligence; Law,,,,Vetenskapsrådet,https://uu.diva-portal.org/smash/get/diva2:1771400/FULLTEXT01 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-505494,http://dx.doi.org/10.1016/j.jbusres.2023.114005,,10.1016/j.jbusres.2023.114005,,,0,000-626-213-535-119; 000-687-817-219-984; 001-797-216-827-486; 001-870-094-461-145; 003-716-694-767-719; 004-142-412-715-782; 007-628-542-317-167; 009-695-690-664-825; 009-759-296-411-264; 010-758-055-681-088; 011-265-215-099-590; 011-576-859-994-660; 011-697-634-088-721; 011-940-140-235-709; 012-115-868-104-505; 012-495-728-525-372; 013-507-404-965-47X; 013-524-854-219-241; 014-324-200-020-559; 014-770-858-748-036; 015-974-587-620-049; 017-750-600-412-958; 019-047-441-786-140; 020-068-773-884-722; 020-162-412-344-350; 020-323-758-379-758; 021-744-232-486-454; 027-450-675-753-333; 028-345-625-505-405; 030-198-382-922-670; 034-215-082-842-06X; 034-931-050-871-701; 035-802-496-064-803; 035-845-444-821-980; 035-934-685-116-38X; 035-966-608-679-994; 036-057-952-562-590; 036-697-206-520-335; 036-807-873-735-545; 038-411-665-812-018; 039-534-744-724-215; 039-551-896-531-361; 039-701-355-200-00X; 039-889-311-499-799; 040-497-970-539-590; 040-646-868-636-817; 040-727-540-049-226; 040-794-946-130-112; 041-427-882-897-219; 041-439-587-474-385; 042-734-356-834-660; 043-518-371-057-580; 045-422-273-148-899; 046-016-590-162-347; 046-389-606-812-052; 046-544-946-496-33X; 046-601-173-802-750; 046-992-864-415-70X; 047-253-407-647-510; 047-614-897-621-33X; 048-079-610-995-663; 048-305-844-152-522; 048-769-882-152-879; 048-918-203-436-463; 048-939-685-334-680; 049-391-379-302-694; 050-164-820-883-73X; 050-609-067-982-963; 050-781-068-517-697; 051-719-141-885-197; 052-048-396-321-002; 052-059-184-928-674; 053-410-387-570-045; 053-776-974-483-575; 053-798-478-432-733; 054-902-760-031-240; 055-894-001-879-725; 057-375-350-333-665; 058-938-007-746-457; 059-346-281-315-411; 062-251-001-546-482; 064-197-484-727-576; 064-281-310-789-971; 065-180-813-080-888; 065-482-302-250-340; 065-826-718-921-167; 065-830-114-849-573; 066-129-090-243-366; 067-695-605-335-378; 068-097-054-319-289; 068-437-284-442-627; 068-747-417-107-907; 070-810-510-965-253; 071-100-570-827-995; 071-838-772-238-137; 071-859-394-001-898; 072-272-699-518-373; 073-231-365-930-259; 074-171-402-399-001; 074-377-751-412-191; 075-824-166-606-487; 076-634-536-489-732; 076-712-234-810-819; 076-727-673-181-753; 078-221-500-625-285; 078-973-000-259-970; 081-518-657-051-430; 083-355-556-547-372; 084-715-149-947-558; 085-849-929-038-961; 086-613-386-899-372; 086-704-748-598-803; 087-139-289-002-712; 091-171-667-311-470; 091-227-420-713-320; 091-475-079-514-506; 091-995-015-657-689; 092-207-313-760-269; 092-704-409-357-332; 096-467-277-570-201; 096-754-761-169-366; 098-414-538-711-29X; 098-570-462-535-502; 098-748-174-665-893; 098-892-891-660-581; 099-118-869-256-834; 100-445-029-445-191; 101-132-838-933-098; 102-088-531-243-659; 106-814-941-065-727; 110-036-312-249-984; 110-399-336-963-990; 111-844-645-213-033; 112-886-757-204-491; 113-229-176-183-174; 113-877-057-647-541; 114-110-874-372-296; 115-086-600-467-983; 116-479-875-912-939; 116-996-726-734-88X; 117-150-892-371-022; 117-605-025-563-331; 120-377-286-133-811; 121-813-144-996-86X; 122-426-088-833-770; 123-150-692-586-544; 123-202-581-406-928; 123-604-104-997-616; 124-651-865-916-428; 124-810-122-682-785; 127-078-628-781-355; 130-736-481-863-638; 132-229-290-194-52X; 132-995-296-305-019; 133-411-816-759-327; 138-377-349-236-695; 141-026-656-461-626; 142-184-726-754-812; 146-655-958-576-211; 149-646-961-781-368; 149-701-090-452-372; 150-064-909-127-41X; 150-822-511-979-962; 151-442-789-438-679; 152-425-818-466-057; 152-673-315-243-452; 164-489-048-543-199; 166-279-300-841-145; 170-587-246-203-79X; 171-857-626-390-922; 179-608-372-698-452; 186-018-077-835-040; 187-565-752-869-922; 194-015-419-850-395,40,true,cc-by,hybrid -120-941-957-122-422,Management research and the impact of COVID-19 on performance: a bibliometric review and suggestions for future research,2022-09-30,2022,journal article,Future Business Journal,23147210; 23147202,Springer Science and Business Media LLC,,Kingsley Opoku Appiah; Bismark Addai; Wesley Ekuban; Suzzie Owiredua Aidoo; Joseph Amankwah-Amoah,"AbstractAlthough there has been a burgeoning scholarly interest in the effects of COVID-19, the current stream of research remains scattered in different business and management fields and domains. Accordingly, integrative knowledge is needed to drive poignant and relevant examinations of the phenomenon. This study attempts to fill this gap by providing a synthesis of the literature, patterns of research studies, and direction for further development of the field. This study also provides a systematic identification and bibliometric and thematic review of literature, performance analysis, science mapping, and cluster analysis. The study additionally provides suggestions for future research to guide relevant discourse.",8,1,,,Coronavirus disease 2019 (COVID-19); Bibliometrics; Field (mathematics); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Identification (biology); Data science; Engineering ethics; Management science; Computer science; Sociology; Engineering; Medicine; Library science; Disease; Botany; Mathematics; Pathology; Virology; Outbreak; Infectious disease (medical specialty); Pure mathematics; Biology,,,,,https://fbj.springeropen.com/counter/pdf/10.1186/s43093-022-00149-1 https://doi.org/10.1186/s43093-022-00149-1,http://dx.doi.org/10.1186/s43093-022-00149-1,,10.1186/s43093-022-00149-1,,,0,001-230-855-524-978; 001-674-350-315-019; 002-977-007-750-480; 003-531-658-007-607; 005-077-106-346-614; 005-300-698-550-81X; 011-523-623-132-598; 011-581-733-025-65X; 012-259-235-781-461; 012-544-800-416-516; 013-507-404-965-47X; 014-838-118-149-423; 017-750-600-412-958; 017-825-886-969-869; 018-893-593-725-44X; 025-214-754-243-190; 028-082-447-557-453; 028-099-637-658-117; 029-420-167-353-195; 030-587-487-070-848; 030-950-296-218-305; 033-171-354-077-456; 036-264-418-039-005; 037-075-494-221-566; 037-811-428-145-318; 038-340-316-557-746; 038-748-938-875-748; 041-483-555-903-438; 042-003-932-773-730; 045-583-595-323-220; 045-884-267-016-474; 047-291-734-468-955; 048-389-431-174-425; 058-633-654-217-626; 060-260-458-224-936; 061-089-418-130-977; 061-439-583-278-630; 062-201-347-440-946; 065-585-713-350-129; 067-461-470-339-184; 068-824-767-000-76X; 070-273-057-201-456; 074-628-399-557-992; 078-986-343-324-626; 080-606-314-550-741; 083-233-429-885-517; 091-908-609-867-829; 096-390-745-778-968; 099-202-267-431-297; 099-690-322-600-715; 100-032-943-238-105; 100-385-564-705-23X; 101-752-490-869-458; 106-811-496-079-691; 107-339-574-834-868; 109-826-931-205-586; 111-591-335-517-282; 113-528-280-129-768; 114-553-504-051-682; 115-942-242-320-656; 120-975-417-040-341; 123-129-712-949-386; 124-931-561-664-571; 126-334-261-467-813; 133-705-850-118-519; 143-736-275-631-256; 143-758-800-295-869; 144-357-277-294-288; 145-126-402-454-825; 150-452-132-911-671; 154-984-777-371-02X,5,true,cc-by,gold -121-114-714-264-570,Bibliometric analysis of surface water detection and mapping using remote sensing in South America,2023-01-28,2023,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Rodrigo N. Vasconcelos; Diego Pereira Costa; Soltan Galano Duverger; Jocimara S. B. Lobão; Elaine C. B. Cambuí; Carlos A. D. Lentini; André T. Cunha Lima; Juliano Schirmbeck; Deorgia Tayane Mendes; Washington J. S. Franca Rocha; Milton J. Porsani,,128,3,1667,1688,Scopus; Context (archaeology); Globe; Data science; Scientific literature; Remote sensing; Bibliometrics; Trend analysis; Geography; Computer science; Library science; Political science; Geology; Archaeology; Medicine; Paleontology; MEDLINE; Machine learning; Law; Ophthalmology,,,,,,http://dx.doi.org/10.1007/s11192-022-04570-9,,10.1007/s11192-022-04570-9,,,0,002-052-422-936-00X; 004-135-861-760-954; 005-146-293-559-557; 009-286-240-384-618; 013-507-404-965-47X; 016-747-449-949-272; 019-075-071-394-366; 027-961-674-417-156; 034-996-942-263-469; 035-376-176-890-349; 035-910-741-165-578; 036-894-327-094-179; 041-899-632-545-558; 043-370-320-492-293; 043-625-599-849-916; 045-175-187-189-197; 047-273-317-607-724; 052-293-533-225-383; 053-462-498-628-056; 058-449-619-398-150; 065-627-045-676-141; 067-268-098-286-068; 068-085-593-771-380; 068-895-496-768-264; 071-217-751-444-52X; 072-374-990-987-279; 073-874-915-127-209; 074-836-419-417-660; 083-385-978-677-780; 084-574-042-577-319; 085-282-156-300-395; 093-582-954-163-828; 107-818-416-750-376; 109-271-396-864-507; 113-709-133-787-376; 116-854-333-114-811; 121-140-428-420-340; 128-022-195-978-227; 134-855-099-366-590; 168-073-540-581-214,5,false,, -121-277-989-847-253,Scientometric analysis of Indian Orthopaedic Research in the last two decades.,2022-07-27,2022,journal article,International orthopaedics,14325195; 03412695,Springer Science and Business Media LLC,Germany,Raju Vaishya; Brij Mohan Gupta; Mallikarjun Kappi; Abhishek Vaish,,46,11,2471,2481,Scopus; Medicine; Specialty; Publishing; Subject (documents); Library science; Orthopedic surgery; MEDLINE; Family medicine; Political science; Surgery; Computer science; Law,Bibliometrics; India; Orthopedics; Research; Scientometrics,Bibliometrics; Biocompatible Materials; Biomedical Research; Child; Humans; Hydroxyapatites; Orthopedic Procedures; Orthopedics,Biocompatible Materials; Hydroxyapatites,,,http://dx.doi.org/10.1007/s00264-022-05523-w,35882640,10.1007/s00264-022-05523-w,,,0,002-813-284-865-971; 003-430-501-532-961; 006-141-215-763-054; 009-014-592-946-478; 009-037-758-578-663; 015-606-693-450-507; 034-293-275-762-422; 038-910-001-572-556; 040-479-954-123-561; 041-192-906-706-840; 044-808-566-509-681; 046-395-520-624-57X; 053-570-332-174-283; 056-732-392-901-882; 061-749-592-240-056; 068-829-584-026-513; 073-418-725-797-114; 074-475-952-428-535; 089-061-720-968-561; 091-441-936-905-013; 152-199-530-794-470,12,false,, -121-465-384-973-095,Microbial pesticides: a bibliometric analysis of global research trends (1973–2024),2025-01-11,2025,journal article,Egyptian Journal of Biological Pest Control,25369342; 11101768,Springer Science and Business Media LLC,Egypt,Weerachon Sawangproh; Paiphan Paejaroen; Lutfi Afifah; Chetsada Phaenark,"Abstract; Background; Microbial pesticides, derived from microorganisms such as bacteria, fungi, and viruses, present sustainable alternatives to chemical pesticides, thereby promoting environmentally friendly agricultural practices. This bibliometric analysis examines the evolution of microbial pesticide research from 1973 to October 2024, utilizing the Scopus database to identify trends, geographic distribution, collaboration networks, and key research areas.; ; Results; A total of 247 articles were analyzed, revealing an annual growth rate of 5.16%, with a significant increase in publications over recent decades. This upward trend indicates a shift towards ecologically conscious pest management. China leads in research output with 341 publications, followed by USA (227) and India (126), highlighting strong international collaboration, particularly between China and USA, where many publications are co-authored by researchers from multiple countries. The primary research areas include Agricultural and Biological Sciences, alongside substantial contributions from Environmental Science and Immunology. The analysis identified thematic clusters, emphasizing key microbial agents such as Bacillus thuringiensis for pest control agent. Key journals, including Biocontrol Science and Technology, Journal of Biopesticides, and Journal of Invertebrate Pathology, serve as essential platforms for disseminating these findings.; ; Conclusion; The findings reflect an increasing recognition of microbial pesticides in integrated pest management, aligning with global trends toward sustainable agricultural practices and food safety by reducing reliance on chemical pesticides. Contributions from institutions such as Fujian Agriculture and Forestry University and Guizhou University in China further highlight the academic support driving advancements in this field.; ",35,1,,,Biology; Pesticide; Biotechnology; Ecology,,,,,,http://dx.doi.org/10.1186/s41938-025-00840-9,,10.1186/s41938-025-00840-9,,,0,001-685-041-889-274; 008-623-344-620-185; 008-883-024-639-638; 010-110-154-628-782; 011-301-822-302-672; 013-507-404-965-47X; 015-542-421-081-031; 015-918-278-118-868; 017-245-470-031-622; 017-881-324-180-491; 019-367-209-050-545; 019-764-117-584-856; 022-640-855-696-271; 024-632-271-964-757; 024-747-825-258-919; 025-711-809-355-243; 025-869-820-248-879; 026-988-354-616-352; 027-053-719-915-404; 027-235-949-315-751; 028-977-226-886-621; 030-604-043-960-251; 032-730-231-902-892; 034-413-949-827-282; 036-240-968-650-718; 036-642-810-009-48X; 049-378-843-617-635; 050-353-341-858-142; 055-577-765-052-948; 056-919-736-753-116; 057-803-697-074-453; 064-780-048-634-590; 067-978-323-701-560; 076-373-262-809-133; 079-831-549-453-781; 084-567-373-463-468; 084-581-673-760-588; 091-898-776-283-154; 096-235-949-932-621; 097-177-213-882-223; 099-321-639-521-640; 105-678-705-197-04X; 108-496-993-236-673; 108-585-891-295-511; 120-100-076-656-647; 125-500-166-169-070; 127-875-649-030-165; 128-361-210-467-764; 134-324-643-128-56X; 134-442-996-293-285; 141-130-032-499-829; 146-243-503-662-382; 151-263-811-949-077; 155-704-143-963-426; 157-267-099-952-518; 168-044-050-004-630; 171-382-844-677-87X; 172-204-943-605-948; 172-452-142-994-210; 179-016-794-170-536; 187-612-558-304-96X,1,true,cc-by,gold -121-500-050-788-106,Ethics in product marketing: a bibliometric analysis,2023-02-21,2023,journal article,Asian Journal of Business Ethics,22106723; 22106731,Springer Science and Business Media LLC,,Manoj Kumar Kamila; Sahil Singh Jasrotia,,12,2,151,174,Product (mathematics); Marketing research; Marketing; Scopus; Sustainability; Marketing management; Quantitative marketing research; Business; Consumption (sociology); Marketing science; Process (computing); Knowledge management; Business marketing; Relationship marketing; Sociology; Political science; Computer science; Social science; Ecology; Geometry; Mathematics; MEDLINE; Law; Biology; Operating system,,,,,,http://dx.doi.org/10.1007/s13520-023-00168-3,,10.1007/s13520-023-00168-3,,,0,000-271-064-673-971; 001-583-573-247-216; 002-052-422-936-00X; 003-397-336-094-395; 004-595-936-054-286; 005-990-915-055-817; 006-679-452-005-884; 008-728-146-709-841; 010-953-212-965-409; 011-965-057-901-249; 012-880-855-052-37X; 013-470-340-804-274; 013-941-816-844-967; 018-552-507-039-270; 019-889-029-652-264; 022-407-061-865-984; 023-739-624-312-986; 026-847-479-131-616; 030-496-534-099-173; 030-662-839-520-126; 030-978-567-379-691; 032-428-973-192-343; 034-123-013-825-348; 035-813-611-775-146; 036-111-727-661-490; 037-020-883-340-106; 039-750-212-932-917; 044-234-131-566-45X; 044-858-555-385-906; 044-868-589-907-628; 046-493-011-792-574; 049-120-262-324-414; 049-426-217-615-353; 050-378-018-741-148; 052-814-152-915-891; 053-180-189-646-300; 053-777-450-199-199; 056-251-168-822-453; 061-942-451-036-996; 065-865-037-847-135; 066-106-570-105-622; 069-389-700-527-594; 076-855-337-636-09X; 077-811-940-103-863; 077-872-764-062-984; 080-608-423-168-380; 082-282-603-501-780; 083-092-180-889-70X; 083-502-862-825-93X; 084-620-320-144-316; 085-541-732-518-40X; 088-361-965-911-879; 093-042-543-629-171; 094-189-928-416-671; 096-312-774-078-799; 098-782-713-711-860; 099-401-243-975-523; 099-640-180-275-447; 099-912-710-458-23X; 100-270-690-702-304; 100-362-935-096-225; 103-379-851-474-647; 106-038-234-954-972; 107-183-170-356-021; 107-243-247-361-120; 109-979-454-422-621; 110-082-088-677-462; 112-565-796-968-753; 117-596-719-639-247; 118-517-694-556-418; 119-877-006-316-02X; 121-208-879-829-725; 125-156-148-209-26X; 129-557-005-016-738; 129-973-715-088-544; 131-788-291-466-106; 133-546-417-719-596; 135-826-014-952-077; 139-257-192-274-553; 150-213-182-788-060; 150-645-735-702-044; 162-183-029-022-123; 169-871-460-493-989; 184-482-048-409-436; 189-056-695-069-474,9,false,, -121-603-506-756-068,LÓGICA FUZZY APLICADA NA PRODUTIVIDADE DA CENOURA,,2022,journal article,Revista SODEBRAS,18093957,Revista SODEBRAS,,E. Z. Godinho; F. L. Caneppele; S. D. M. Hasan,"The professional nurse, when dealing with a patient, often experiences adverse situations in their work environment. This can affect their health. In order to know about this daily life, the present study aimed to carry out a bibliometric analysis on the theme Burnout in nurses where, in a more punctual way, we sought to identify the main predictors of Burnout of this profession from recent international publications. In the first part of the study, the software R (bibliometrix package) was used. Burnout predictors were identified from the articles resulting from the bibliometric search. The survey results pointed to an increase in publications over the years with a peak in 2018. The largest contributions in quantitative terms are still from the United States of America. Burnout predictors have an organizational and relational origin. Individual aspects, such as resilience, appear in a relevant way to avoid professional illness.",17,197,62,69,Mathematics; Physics,,,,,http://doi.org/10.29367/issn.1809-3957.17.2022.197.62,http://dx.doi.org/10.29367/issn.1809-3957.17.2022.197.62,,10.29367/issn.1809-3957.17.2022.197.62,,,0,,0,true,,gold -121-652-742-486-910,Comprehensive metrological and content analysis of the public–private partnerships (PPPs) research field: a new bibliometric journey,2020-07-13,2020,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Jiangang Shi; Kaifeng Duan; Guangdong Wu; Rui Zhang; Xiaowei Feng,,124,3,2145,2184,Citation analysis; Field (geography); Content analysis; Domain (software engineering); Data science; Intellectual structure; Computer science; Knowledge base,,,,National Social Science Foundation of China; National Natural Science Foundation of China; National Natural Science Foundation of China,https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics124.html#ShiDWZF20 https://doi.org/10.1007/s11192-020-03607-1 https://ideas.repec.org/a/spr/scient/v124y2020i3d10.1007_s11192-020-03607-1.html https://link.springer.com/10.1007/s11192-020-03607-1,http://dx.doi.org/10.1007/s11192-020-03607-1,,10.1007/s11192-020-03607-1,3043717094,,0,000-027-332-707-855; 001-184-335-477-368; 001-978-062-012-040; 002-010-102-935-66X; 002-034-077-419-490; 002-052-422-936-00X; 003-155-386-683-807; 003-290-831-040-749; 003-527-807-812-30X; 005-171-179-204-933; 005-317-360-717-564; 006-190-345-716-88X; 006-678-699-823-614; 007-089-067-951-619; 007-306-993-454-214; 008-608-388-748-513; 008-986-683-131-565; 009-015-385-731-68X; 009-638-682-509-293; 010-051-849-809-072; 010-171-819-922-943; 011-016-603-830-704; 011-424-290-833-64X; 011-906-251-148-262; 012-970-314-086-162; 013-070-083-310-149; 013-507-404-965-47X; 013-810-469-830-826; 015-313-694-925-851; 016-502-085-897-567; 016-609-440-436-846; 017-515-582-557-829; 020-613-723-286-995; 021-775-005-542-657; 022-607-196-284-796; 022-615-686-687-192; 022-774-738-500-720; 022-853-432-596-593; 023-216-754-355-332; 024-324-924-958-705; 024-486-069-790-13X; 026-627-541-766-213; 026-915-337-513-59X; 027-685-097-105-487; 027-772-063-414-105; 028-965-240-936-21X; 031-417-088-356-229; 032-169-393-071-306; 032-459-404-386-908; 033-785-361-785-318; 035-483-284-362-272; 037-949-718-505-053; 038-691-672-320-571; 039-801-005-017-65X; 042-252-359-421-579; 042-618-760-333-536; 044-740-743-681-645; 045-493-640-317-534; 045-789-854-501-903; 046-067-091-661-90X; 047-134-478-431-993; 049-309-555-163-764; 050-889-108-753-77X; 051-647-739-244-271; 051-898-184-837-853; 054-189-394-603-884; 055-416-159-026-531; 056-717-640-577-386; 057-367-696-455-520; 059-682-346-948-651; 060-402-895-217-188; 060-598-249-212-97X; 061-024-541-009-614; 068-963-905-554-251; 069-431-893-536-433; 069-921-992-742-701; 076-711-686-740-917; 081-262-510-588-237; 081-287-243-004-479; 082-723-047-193-406; 083-260-285-886-548; 084-164-240-895-172; 084-384-041-071-888; 086-104-811-552-391; 087-986-534-603-210; 088-397-995-255-782; 088-719-588-015-860; 089-575-517-323-563; 091-687-132-263-836; 093-413-948-838-393; 093-749-572-908-363; 095-051-858-962-021; 098-436-005-750-541; 098-988-803-056-998; 099-167-558-008-199; 101-752-490-869-458; 104-563-576-763-650; 105-595-185-566-193; 110-335-528-211-037; 113-183-912-278-93X; 113-272-264-160-400; 115-054-741-816-773; 115-640-830-591-029; 117-958-925-859-887; 123-202-581-406-928; 124-753-295-414-123; 125-571-130-490-557; 130-420-337-237-711; 130-652-730-017-494; 131-237-630-250-510; 132-643-727-138-058; 133-880-650-913-305; 137-516-588-409-566; 145-623-132-391-699; 146-208-436-691-12X; 152-474-469-594-608; 156-621-936-340-328; 161-618-739-781-988; 170-303-022-064-148; 179-314-629-397-61X,81,false,, -121-673-670-696-347,Application trends and research hotspots of endoscopic enucleation of the prostate: a bibliometric and visualization analysis.,2025-02-26,2025,journal article,World journal of urology,14338726; 07244983,Springer Science and Business Media LLC,Germany,Xiao-Da Lan; Zhuo-Yang Yu; Rui Jiang; Zhi-Cun Li; Lei Yang; Kai Zhang; Yi-Sen Meng; Qian Zhang,"Endoscopic enucleation of the prostate (EEP) is a preferred treatment for benign prostatic hyperplasia (BPH). This bibliometric analysis aims to analyze the application trends and research hotspots of EEP.; We conducted a bibliometric analysis of publications indexed in the Web of Science Core Collection from 1989 to 2023. The techniques examined include holmium laser enucleation (HoLEP), thulium laser enucleation (ThuLEP/ThuFLEP), bipolar/monopolar transurethral enucleation (b-TUEP/m-TUEP), GreenLight laser enucleation (GreenLEP), and diode laser enucleation (DiLEP). We utilized VOSviewer, CiteSpace, and the R package 'bibliometrix' for the analysis.; A total of 739 English-language studies were analyzed, revealing a steady increase in EEP-related publications. HoLEP was the most extensively studied technique, followed by ThuLEP and b-TUEP, while ThuFLEP gaining emerging interest. There has been a notable lack of high-quality randomized controlled trials (RCTs) for GreenLEP, DiLEP and m-TUEP. China, the United States, and Germany led in publication volume and collaboration networks. Key contributors in the field were identified, with recent research focusing on topics like postoperative transient urinary incontinence (TUI) and the role of robot-assisted simple prostatectomy (RASP) in comparison to EEP.; EEP is gaining widespread clinical acceptance for BPH treatment. Future research should focus on addressing the gap in high-quality RCTs, especially for underexplored techniques like GreenLEP, DiLEP and m-TUEP, and explore strategies to reduce postoperative TUI. Prospective comparisons between RASP and EEP will be crucial for optimizing surgical approaches in BPH management.; © 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",43,1,140,,Medicine; Enucleation; Nephrology; Visualization; Prostate; Bibliometrics; Urology; Internal medicine; General surgery; Surgery; Library science; Data mining; Computer science; Cancer,Benign prostatic hyperplasia; Endoscopic enucleation; HoLEP; Laser enucleation; ThuLEP,Humans; Prostatic Hyperplasia/surgery; Male; Bibliometrics; Prostatectomy/methods; Endoscopy/methods; Laser Therapy/methods,,The Special Foundation for National Key Research and Development Program of China (Grant No. 2022YFC3602902); National High Level Hospital Clinical Research Funding (2023IR43，2023CX01),,http://dx.doi.org/10.1007/s00345-024-05379-2,40009250,10.1007/s00345-024-05379-2,,,0,000-373-942-260-108; 000-533-577-993-302; 001-334-867-219-854; 001-446-392-977-390; 002-052-422-936-00X; 004-331-904-177-039; 009-133-789-806-227; 009-886-768-993-410; 009-982-970-870-65X; 011-563-529-004-916; 013-507-404-965-47X; 013-599-685-083-73X; 014-426-477-392-125; 016-839-580-479-710; 017-076-997-773-804; 024-701-727-378-411; 029-926-856-153-859; 031-290-910-298-663; 032-426-978-869-094; 033-972-679-244-507; 034-145-218-792-807; 034-835-296-079-060; 036-163-091-538-925; 036-328-197-031-973; 039-533-799-603-301; 040-178-935-218-910; 042-468-246-763-92X; 044-128-166-854-76X; 045-553-587-239-814; 046-077-135-486-824; 049-338-911-219-510; 053-984-416-586-744; 055-390-299-439-108; 058-736-731-015-633; 060-013-523-938-073; 064-321-929-781-942; 064-400-499-357-900; 069-356-468-594-950; 070-915-929-049-925; 071-883-012-101-843; 095-310-819-501-816; 095-518-179-663-480; 104-079-555-425-156; 107-638-914-151-749; 116-917-606-035-904; 120-623-010-272-58X; 121-592-450-248-118; 123-202-581-406-928; 131-454-630-057-746; 148-068-001-902-240; 155-955-320-476-917; 157-323-656-476-918; 196-411-808-545-316,0,true,,green -121-813-144-996-86X,Franchising research on emerging markets: Bibliometric and content analyses,,2021,journal article,Journal of Business Research,01482963,Elsevier BV,Netherlands,Vanessa Pilla Galetti Bretas; Ilan Alon,"Abstract This study reviews the franchising literature on emerging markets. We used the Bibliometrix R-package and VOSviewer software to perform a bibliometric analysis of 297 articles between 1989 and 2020 obtained from the Scopus database. We combined bibliometric coupling, historiographic citation, keyword co-occurrence, and conceptual thematic analysis, with a content analysis of the most cited articles based on total global and local citations. We identified two main research clusters: international franchising and social franchising. This article provides a deep understanding of the intellectual and conceptual structure of the academic field. It complements existing qualitative reviews and attempts at characterizations, and suggests future research directions.",133,,51,65,Emerging markets; Content analysis; Political science; Citation; Conceptual structure; Bibliometric analysis; Knowledge management; Thematic analysis; Scopus,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior,https://ideas.repec.org/a/eee/jbrese/v133y2021icp51-65.html https://www.sciencedirect.com/science/article/pii/S0148296321003118 https://www.sciencedirect.com/science/article/abs/pii/S0148296321003118,http://dx.doi.org/10.1016/j.jbusres.2021.04.067,,10.1016/j.jbusres.2021.04.067,3162153788,,0,001-068-643-811-649; 001-187-191-963-888; 003-976-701-551-264; 005-425-568-391-848; 005-483-031-535-245; 005-644-198-664-908; 007-985-708-677-601; 010-083-219-835-969; 010-163-096-509-986; 011-127-002-371-882; 011-579-898-445-57X; 012-218-286-526-144; 012-782-405-438-321; 013-507-404-965-47X; 013-658-614-078-578; 013-748-721-280-789; 014-497-461-187-651; 017-045-209-476-752; 017-422-215-354-285; 017-750-600-412-958; 018-462-835-184-144; 021-482-762-936-187; 022-422-987-593-412; 025-414-002-380-13X; 031-588-513-576-641; 032-110-047-804-486; 032-272-752-992-955; 033-339-053-376-387; 034-597-001-035-749; 036-735-023-641-446; 037-795-985-384-058; 038-028-654-323-612; 038-621-324-143-915; 038-887-539-684-266; 038-991-994-098-031; 039-698-766-416-396; 040-044-567-204-246; 040-115-973-005-942; 040-459-976-597-604; 041-249-182-843-747; 041-272-295-929-825; 043-875-163-999-78X; 045-976-089-309-597; 046-464-832-609-295; 047-525-273-086-581; 047-554-788-068-027; 048-019-177-775-947; 048-247-137-087-618; 049-391-379-302-694; 051-730-197-035-05X; 052-603-569-095-390; 054-584-970-801-126; 055-490-472-565-529; 055-570-555-708-02X; 056-809-515-326-80X; 057-047-828-619-708; 058-919-727-408-727; 059-294-408-408-534; 060-392-861-603-56X; 064-112-115-116-272; 064-501-747-296-020; 065-300-034-038-465; 066-875-021-210-020; 068-586-998-914-138; 069-932-093-103-280; 072-376-656-954-235; 073-205-726-823-661; 078-381-607-373-703; 082-168-138-680-912; 083-232-682-111-086; 085-219-658-241-450; 091-423-577-584-780; 091-560-056-600-117; 096-334-751-499-467; 102-088-531-243-659; 102-126-480-535-938; 102-495-808-026-55X; 103-207-090-026-127; 103-214-949-434-277; 104-495-326-573-684; 107-663-559-122-082; 113-277-592-251-339; 114-206-127-346-533; 120-340-827-549-678; 123-457-102-588-651; 128-297-501-122-666; 130-154-741-982-60X; 136-061-294-870-264; 136-096-906-465-105; 137-693-432-804-786; 139-221-923-372-065; 143-936-693-364-687; 146-301-569-452-09X; 147-748-748-521-465; 148-121-420-265-741; 149-228-754-084-402; 150-718-894-798-56X; 160-218-744-714-844; 161-233-301-896-193; 167-871-310-551-431; 175-723-682-262-951; 185-059-218-401-751; 191-450-331-119-538,145,true,cc-by,hybrid -121-945-544-068-477,"Competencia digital, profesorado y educación superior",2023-02-08,2023,journal article,HUMAN REVIEW. International Humanities Review / Revista Internacional De Humanidades,26959623,Eurasia Academic Publishing Group,,Andrés Cisneros-Barahona; Luis Marqués Molías; Nicolay Samaniego-Erazo; María Isabel Uvidia-Fassler; Wilson Castro-Ortiz; Henry Villa-Yánez,"Using the Bibliometrix software package and the Prisma Guide, a bibliometric analysis of the literature from the Web of Science on university teaching digital competence was developed. Research is delimited through Eric’s thesauri. Research questions related to data sources, authors, and collaborative networks were raised. The research shows increases in production as of 2019, the nationality of the authors and the affiliation of institutions stand out through extensive research networks in Ibero-America. It is necessary to extend this study to other scientific bases.",16,5,1,20,,,,,,,http://dx.doi.org/10.37819/revhuman.v16i5.1527,,10.37819/revhuman.v16i5.1527,,,0,001-207-501-099-42X; 001-451-636-355-843; 003-190-802-899-804; 003-722-251-461-869; 003-872-675-322-364; 006-068-362-798-128; 007-322-400-569-332; 007-734-976-791-420; 010-824-958-921-305; 014-939-994-984-923; 015-170-428-339-678; 017-223-012-396-918; 017-394-279-330-244; 019-609-049-036-080; 020-184-794-627-889; 021-792-723-475-967; 023-885-170-368-525; 025-821-538-253-591; 029-510-581-755-316; 042-016-589-369-361; 046-914-262-733-168; 050-516-636-125-468; 052-505-813-320-897; 054-776-041-446-795; 054-902-233-912-433; 056-157-601-516-617; 059-283-456-947-256; 064-988-019-412-326; 065-961-020-425-059; 067-802-630-985-170; 069-906-713-629-998; 079-721-148-600-456; 087-903-294-097-024; 093-904-117-475-655; 104-489-077-105-239; 118-314-694-859-187; 118-805-369-132-781; 123-200-079-644-42X; 125-420-212-519-87X; 128-172-611-288-449; 139-937-031-195-626; 144-747-565-316-983; 145-035-299-045-615; 164-267-516-952-417; 168-546-950-987-37X,0,false,, -122-172-879-454-278,A bibliometric analysis of pricing models in supply chain,2021-06-11,2021,journal article,Journal of Revenue and Pricing Management,14766930; 1477657x,Springer Science and Business Media LLC,United Kingdom,Syed Asif Raza,,21,2,228,251,,,,,,,http://dx.doi.org/10.1057/s41272-021-00329-8,,10.1057/s41272-021-00329-8,,,0,000-200-650-431-926; 000-477-995-869-60X; 000-544-822-522-736; 001-435-788-287-309; 001-564-295-021-407; 002-894-887-319-862; 003-267-936-675-008; 003-830-847-913-158; 004-286-988-190-889; 005-927-916-381-831; 006-519-822-028-897; 006-842-725-856-471; 007-338-827-012-855; 007-546-207-551-205; 007-940-337-103-908; 009-459-237-595-580; 009-519-282-986-267; 009-679-172-880-106; 009-771-909-042-839; 010-093-409-154-231; 010-201-564-322-309; 012-418-802-673-332; 012-589-138-796-225; 012-721-297-532-45X; 013-135-546-244-999; 013-169-733-493-769; 013-269-963-798-312; 013-507-404-965-47X; 013-828-119-780-609; 013-916-115-821-83X; 014-421-739-068-008; 015-039-374-761-57X; 015-558-464-764-939; 015-857-128-495-100; 016-293-547-479-557; 016-815-538-549-803; 016-949-406-406-775; 017-285-497-379-625; 017-823-138-893-855; 017-874-592-300-212; 017-905-363-700-043; 018-135-102-856-670; 018-986-610-171-948; 019-183-323-400-733; 019-726-772-852-880; 020-730-805-827-313; 021-523-129-971-364; 021-628-427-748-567; 022-732-349-833-024; 022-775-170-514-891; 022-838-235-534-283; 022-923-209-033-502; 023-654-030-797-362; 023-660-445-332-154; 024-540-759-559-028; 024-585-721-629-835; 025-692-508-203-165; 026-574-806-869-722; 027-736-410-582-923; 028-474-522-294-167; 031-017-067-892-556; 031-693-976-566-073; 033-553-945-112-157; 033-718-066-350-717; 034-804-824-275-400; 034-828-267-152-227; 035-371-452-798-643; 035-686-535-515-086; 038-120-820-425-836; 039-784-434-464-747; 040-006-828-379-822; 040-328-444-178-513; 040-579-653-353-548; 041-186-073-223-72X; 041-618-312-868-282; 041-852-083-658-18X; 041-956-028-914-327; 042-791-559-025-055; 042-993-464-838-032; 043-639-650-762-144; 044-486-509-005-525; 044-527-412-346-25X; 044-540-895-617-144; 045-661-361-832-023; 045-911-927-455-415; 046-263-840-020-738; 046-838-894-475-855; 046-995-191-168-647; 047-626-400-861-679; 048-593-878-694-935; 049-870-709-984-017; 050-900-840-826-583; 050-967-955-336-441; 051-338-459-342-599; 053-598-695-896-482; 053-849-661-254-231; 053-904-667-455-914; 054-501-717-475-789; 054-703-150-198-121; 056-251-272-657-857; 056-690-559-983-144; 057-130-805-097-801; 057-342-864-512-491; 057-419-501-499-34X; 057-494-534-669-667; 057-876-308-513-756; 058-264-021-351-517; 058-939-848-420-018; 060-611-372-963-705; 060-916-861-070-606; 063-162-417-586-607; 063-829-284-493-409; 064-407-579-296-062; 065-291-636-344-492; 065-676-179-160-07X; 066-105-967-446-906; 070-078-980-200-808; 070-991-282-066-330; 071-178-320-297-08X; 071-878-554-659-597; 072-494-844-539-810; 072-569-391-426-250; 074-360-769-572-520; 076-093-023-692-613; 077-064-550-395-024; 077-226-277-808-981; 077-412-098-836-193; 078-125-369-788-459; 078-957-513-246-34X; 079-540-457-572-185; 079-999-323-575-726; 080-436-406-243-416; 081-243-634-616-662; 081-818-820-792-621; 084-203-530-445-013; 085-405-750-840-797; 085-912-477-763-634; 086-908-849-223-255; 087-092-518-070-677; 088-080-254-273-478; 089-872-655-420-557; 095-083-258-120-580; 095-519-461-898-333; 096-087-310-333-52X; 096-550-862-701-871; 098-605-177-583-799; 098-655-704-541-028; 100-106-431-627-368; 101-945-350-229-636; 104-495-326-573-684; 104-525-664-524-652; 104-719-477-229-426; 106-193-773-021-434; 106-443-294-168-411; 107-218-133-777-158; 108-775-769-677-863; 110-847-975-678-893; 111-402-413-475-992; 111-415-203-866-98X; 111-867-041-984-47X; 112-927-756-908-655; 117-824-914-149-333; 118-768-095-417-156; 122-489-106-483-929; 126-936-699-853-67X; 128-100-581-455-505; 129-259-017-796-289; 130-222-984-820-770; 130-352-984-739-230; 130-513-072-020-80X; 131-251-983-229-400; 132-027-041-411-524; 133-741-015-849-797; 133-749-865-588-067; 134-852-243-291-965; 139-314-009-295-312; 139-491-013-515-362; 142-724-397-716-907; 143-283-913-547-907; 143-655-125-023-189; 145-167-457-823-342; 146-851-993-277-91X; 147-585-696-772-719; 157-230-978-910-163; 157-661-866-307-831; 157-733-552-760-537; 160-989-639-610-563; 161-844-521-429-661; 173-237-829-696-29X; 175-346-386-090-509; 177-781-272-534-799; 179-332-574-380-288; 196-254-669-090-799,1,false,, -122-259-350-453-007,ANÁLISES BIBLIOMÉTRICAS: UM PROCESSO OPERACIONAL PADRÃO UTILIZANDO O SOFTWARE R E O BIBLIOMETRIX,2024-11-19,2024,book chapter,Pesquisa aplicada: reflexões e práticas para o campo do ensino e da aprendizagem,,Atena Editora,,Leda Goularte Machado; Vera Lúcia Duarte Ferreira; Lisete Funari Dias,,,,26,34,Materials science; Physics,,,,,https://atenaeditora.com.br/catalogo/download-file/7454 https://doi.org/10.22533/at.ed.4522419113,http://dx.doi.org/10.22533/at.ed.4522419113,,10.22533/at.ed.4522419113,,,0,,0,true,,bronze -122-447-370-399-982,The Seeds of the NEH Algorithm: An Overview Using Bibliometric Analysis,2023-12-06,2023,journal article,Operations Research Forum,26622556,Springer Science and Business Media LLC,,Bruno de Athayde Prata; Marcelo Seido Nagano; Nádia Junqueira Martarelli Fróes; Levi Ribeiro de Abreu,,4,4,,,Computer science; Scopus; Citation; Information retrieval; Field (mathematics); Citation analysis; Thematic map; Data science; Bibliometrics; Algorithm; Data mining; Library science; Mathematics; Political science; Geography; Cartography; MEDLINE; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1007/s43069-023-00276-7,,10.1007/s43069-023-00276-7,,,0,000-826-601-090-058; 009-357-550-624-176; 010-979-271-512-130; 013-106-496-482-418; 013-198-205-516-982; 013-507-404-965-47X; 013-524-854-219-241; 014-798-299-054-103; 019-026-189-807-460; 024-656-019-004-232; 027-346-940-831-217; 032-349-792-766-840; 037-991-737-149-970; 050-081-808-932-013; 060-942-804-422-141; 061-975-653-345-878; 063-201-172-236-172; 067-620-206-001-403; 067-854-919-061-512; 068-517-645-657-093; 070-310-058-713-98X; 076-645-107-335-894; 076-697-645-157-786; 081-496-935-263-86X; 086-046-441-769-717; 087-498-917-659-93X; 096-400-946-560-187; 104-875-143-461-465; 105-604-930-843-78X; 109-576-438-413-833; 115-929-505-470-968; 116-586-099-071-017; 121-932-889-456-712; 125-456-541-706-873; 131-296-362-570-066; 151-545-422-183-421; 167-223-282-342-994; 176-217-802-996-904; 188-306-396-113-909; 197-587-605-117-43X; 199-034-688-761-388,4,false,, -123-492-023-330-090,Mapping Research on Waqf History using Bibliometrix,2024-12-03,2024,journal article,International Journal of Waqf,29853591,Sharia Economic Applied Research and Training (SMART) Insight,,Hilmy Abdullah Azzam,"This study aims to see the development of research on the topic of ""Waqf History"" and research plans that can be carried out based on journals published on the theme. This research uses a qualitative method with a bibliometric analysis approach. The data used is secondary data with the theme ""Waqf History"" which comes from the Scopus database with a total of 150 journal articles. Then, the data is processed and analyzed using the VosViewer application with the aim of knowing the bibliometric map of ""Waqf History"" research development in the world. The results of the study found that in bibliometric author mapping the authors who published the most research on the theme of ""Waqf History"" were Memiş Ş.E.; Liebrenz B; Abdullah A.S.; and Orbay K. Furthermore, based on bibliometric keyword mapping, there are 5 clusters with the most used words are development, institution, mosque, manuscript, charity, law, property, role, and land . Then, the topics of research paths related to Waqf History are Ottoman Empire and Waqf Management, Classical Waqf Principles, History of Waqf Activities as Charity, The Role of Scholars in Managing Waqf, and Waqf in Jerusalem during the Ottoman Era.",4,1,,,Waqf; Computer science; History; Archaeology; Islam,,,,,,http://dx.doi.org/10.58968/ijw.v4i1.555,,10.58968/ijw.v4i1.555,,,0,,0,false,, -123-606-995-251-082,Exploring the trend of recognizing apple leaf disease detection through machine learning: a comprehensive analysis using bibliometric techniques,2024-01-30,2024,journal article,Artificial Intelligence Review,15737462; 02692821,Springer Science and Business Media LLC,Netherlands,Anupam Bonkra; Sunil Pathak; Amandeep Kaur; Mohd Asif Shah,"AbstractThis study’s foremost objectives were to scrutinize how unexpected weather affects agricultural output and to assess how well AI-based machine learning and deep leaning algorithms work for spotting apple leaf diseases. The researchers carried out a bibliometric study to obtain understanding of the current research trends, citation patterns, ownership and partnership arrangements, publishing patterns, and other parameters related to early identification of apple illnesses. Comprehensive interdisciplinary scientific maps are limited because syndrome recognition is not restricted to any solitary arena of research, despite the fact that there have been many studies on the identification of apple diseases. By employing a scientometric technique and 109 publications from the Scopus database published between 2011 and 2022, this study attempted to assess the condition of the research area and combine knowledge frameworks. To find important journals, authors, nations, articles, and topics, the study used the automated processes of VOSviewer and Biblioshiny software. Patterns and trends were discovered using citation counts, social network analysis, and citation and co-citation studies.",57,2,,,Computer science; Machine learning; Artificial intelligence; Pattern recognition (psychology),,,,,https://link.springer.com/content/pdf/10.1007/s10462-023-10628-8.pdf https://doi.org/10.1007/s10462-023-10628-8 https://www.researchsquare.com/article/rs-2686136/latest.pdf https://doi.org/10.21203/rs.3.rs-2686136/v1,http://dx.doi.org/10.1007/s10462-023-10628-8,,10.1007/s10462-023-10628-8,,,0,002-052-422-936-00X; 002-403-262-667-446; 003-810-940-769-906; 007-858-551-836-982; 009-002-693-250-279; 009-733-085-038-863; 013-123-426-843-243; 013-507-404-965-47X; 013-758-380-086-011; 018-951-549-465-065; 019-801-800-362-318; 020-062-092-347-983; 022-756-376-485-981; 025-824-143-908-307; 030-758-713-901-296; 033-861-885-717-959; 034-850-729-564-893; 037-777-161-254-593; 040-317-302-886-553; 040-708-704-903-174; 041-361-660-359-643; 046-385-037-912-812; 046-821-912-291-013; 046-992-864-415-70X; 048-596-257-601-218; 049-730-414-762-703; 054-608-939-490-298; 058-062-230-698-474; 058-799-704-000-119; 058-803-884-976-803; 060-169-968-515-218; 060-892-422-368-810; 071-960-154-891-648; 072-009-685-782-773; 074-723-724-537-908; 075-604-209-211-676; 080-178-045-493-313; 080-848-901-955-788; 081-892-840-364-937; 090-710-198-298-499; 091-153-725-612-791; 093-186-636-893-601; 101-259-543-993-366; 105-530-125-329-922; 108-174-766-772-001; 108-371-162-719-413; 108-870-845-626-992; 112-747-581-189-768; 114-086-082-000-577; 133-646-593-125-111; 136-486-259-176-529; 143-698-801-440-640; 146-340-710-814-806; 151-963-527-122-344; 153-105-614-556-02X; 155-235-829-338-482; 159-043-645-262-566; 159-203-392-708-629; 161-426-542-359-867; 163-287-813-843-470; 167-710-086-204-672; 185-882-041-430-071; 186-080-127-235-965; 197-938-108-505-097; 198-598-884-700-205,19,true,cc-by,hybrid -123-635-138-034-262,Quantitative analysis of literature on diagnostic biomarkers of Schizophrenia: revealing research hotspots and future prospects.,2025-03-01,2025,journal article,BMC psychiatry,1471244x,Springer Science and Business Media LLC,United Kingdom,Liuyin Jin; Linman Wu; Jing Zhang; Wenxin Jia; Han Zhou; Shulan Jiang; Pengju Jiang; Yingfang Li; Yang Li,"Schizophrenia (SCZ) is a complex mental disorder characterized by a wide range of symptoms and cognitive impairments. The search for reliable biomarkers for SCZ has gained increasing attention in recent years, as they hold the potential to improve early diagnosis and intervention strategies. To understand the research trends and collaborations in this field, a comprehensive Bibliometric analysis of SCZ and biomarkers research was conducted.; A systematic search of the Web of Science Core Collection was performed to retrieve relevant articles published from January 2000 to July 2023. The search focused on SCZ and biomarkers. Bibliometric tools, including CiteSpace, VOSviewer, and R package Bibliometrix, were utilized to perform data extraction, quantitative analysis, and visualization.; The search focused on SCZ and biomarkers, and a total of 2935 articles were included in the analysis. The analysis revealed a gradual increase in the number of publications related to SCZ and biomarkers over the years, indicating a growing research focus in this area. Collaboration and research activity were found to be concentrated in the United States and Western European countries. Among the top ten most active journals, ""Schizophrenia Research"" emerged as the journal with the highest number of publications and citations related to SCZ and biomarkers. Recent studies published in this journal have highlighted the potential use of facial expressions as a diagnostic biomarker for SCZ, suggesting that facial expression analysis using big data may hold promise for future diagnosis and interventions. Furthermore, the analysis of key research keywords identified inflammatory factors, DNA methylation changes, and glutamate alterations as potential biomarkers for SCZ diagnosis.; This Bibliometric analysis provides valuable insights into the current state of research on SCZ and biomarkers. The identification of reliable biomarkers for SCZ could have significant implications for early diagnosis and interventions, potentially leading to improved outcomes for individuals affected by this challenging mental disorder. Further research and collaborations in this field are encouraged to advance our understanding of SCZ and enhance diagnostic and therapeutic approaches.; © 2025. The Author(s).",25,1,186,,Schizophrenia (object-oriented programming); Schizophrenia research; Psychology; MEDLINE; Medicine; Psychiatry; Data science; Computer science; Biology; Biochemistry,Bibliometrics; Biomarkers; CiteSpace; SCZ; VOSviewer,Schizophrenia/diagnosis; Humans; Biomarkers; Bibliometrics; Biomedical Research,Biomarkers,,,http://dx.doi.org/10.1186/s12888-025-06644-3,40025442,10.1186/s12888-025-06644-3,,PMC11872302,0,000-667-231-896-402; 000-937-061-808-381; 002-052-422-936-00X; 005-011-636-083-514; 006-251-585-515-098; 006-708-431-311-399; 007-500-155-247-91X; 007-577-719-507-357; 007-940-695-828-028; 009-619-660-403-929; 009-936-660-827-472; 012-180-550-497-91X; 012-279-214-231-151; 013-123-944-981-275; 013-341-755-352-600; 013-507-404-965-47X; 022-128-213-771-273; 022-172-474-723-489; 025-140-974-101-320; 026-395-112-558-483; 027-652-377-551-683; 027-843-780-199-212; 028-239-354-231-49X; 029-999-566-737-60X; 031-587-048-340-435; 032-330-090-827-573; 036-527-684-864-405; 036-656-168-693-890; 036-944-645-598-762; 039-449-276-391-184; 041-887-575-169-796; 045-872-051-830-903; 049-941-950-970-047; 050-417-113-340-413; 052-149-855-788-705; 055-112-662-189-108; 064-482-912-103-288; 064-862-138-358-090; 071-576-555-356-543; 071-878-836-294-733; 075-998-256-528-240; 078-425-841-052-563; 078-856-249-707-537; 079-658-305-963-463; 082-250-308-281-846; 086-345-391-695-78X; 093-667-572-293-160; 095-158-247-371-484; 101-493-215-229-241; 103-026-457-796-652; 106-700-147-938-150; 112-742-054-350-30X; 114-041-516-158-170; 117-196-856-417-322; 117-865-133-012-925; 127-925-057-249-502; 137-519-893-615-140; 146-444-445-047-998,0,true,"CC BY, CC0",gold -123-657-241-385-017,Knowledge Atlas and emerging trends on the impact of mindfulness on tumors: a bibliometric analysis,2024-12-26,2024,journal article,Current Psychology,10461310; 19364733,Springer Science and Business Media LLC,United States,Zhongliang Lin; Zeqi Ji; Jinyao Wu; Huiting Tian; Qiuping Yang; Lingzhi Chen; Jiehui Cai; Daitian Zheng; Zhiyang Li; Yexi Chen,"The affliction of tumors presents a formidable health challenge all over the world. Meanwhile, the possible therapeutic effects of mindfulness on tumors are gradually being explored. This article aims to conduct a bibliometric investigation into the potential impact of mindfulness on tumors. All related publications on mindfulness and tumors were retrieved from the Web of Science Core Collection database. Bibliometric analysis tools (Biblioshiny, Citespace, VOSviewer) and Microsoft Excel were employed to draw a knowledge atlas and emerging trends by analyzing the number of articles, authors, countries/regions, institutions, journals, articles, references, and keywords. A total of 1,125 articles on mindfulness and tumors were included from 2013 to 2022, with an annual growth rate of 15.63%. Most of these articles originated from the USA, China, and Canada. Psycho-Oncology and Mindfulness are both significant journals in this field on a global scale. Carlson LE stands out as the most influential, with the highest number of publications and citations. Breast cancer is the most studied cancer in mindfulness-based interventions. Quality of life, stress reduction, depression and anxiety are hot topics of research. Mindfulness may play an valuable role in cancer treatment. Further exploration may focus on the underlying mechanisms of mindfulness on tumors. This bibliometric analysis describes the current state and hotspots in this field and provides crucial leads for future scientific strategies and research directions.",44,1,647,660,Psychology; Mindfulness; Atlas (anatomy); Clinical psychology; Medicine; Anatomy,,,,Special Fund Project of Guangdong Science and Technology; Medical Scientific Research Foundation of Guangdong Province; Shantou Medical Science and Technology Planning Project,,http://dx.doi.org/10.1007/s12144-024-06876-8,,10.1007/s12144-024-06876-8,,,0,002-052-422-936-00X; 005-009-329-187-45X; 017-235-869-594-583; 019-176-809-446-20X; 019-241-508-797-784; 020-080-046-935-409; 026-339-911-640-292; 026-635-872-781-020; 026-737-795-245-204; 028-418-433-176-20X; 029-936-549-954-153; 030-806-787-422-793; 033-559-440-891-439; 035-031-988-615-904; 035-700-225-284-401; 036-656-168-693-890; 037-223-185-741-594; 040-706-099-157-660; 044-316-310-315-612; 046-666-148-271-609; 051-905-317-081-07X; 054-792-053-951-078; 057-175-721-889-43X; 057-627-627-935-879; 063-079-778-045-497; 064-835-780-827-356; 074-819-170-230-213; 075-567-840-374-274; 080-126-235-203-503; 080-580-902-275-632; 082-250-308-281-846; 101-148-505-586-67X; 106-483-971-474-931; 107-483-302-885-238; 123-648-657-208-706; 141-978-863-969-770; 142-988-518-894-005; 152-347-258-609-708; 152-882-906-726-019; 155-270-274-174-042; 190-899-673-514-507,0,true,cc-by-nc-nd,hybrid -123-735-375-829-569,Bibliometric analysis of the Vogt‒Koyanagi‒Harada disease literature.,2023-08-08,2023,journal article,International ophthalmology,15732630; 01655701,Springer Science and Business Media LLC,Netherlands,Liangpin Li; Liyun Yuan; Xueyan Zhou; Xia Hua; Xiaoyong Yuan,"As an autoimmune disease, Vogt‒Koyanagi‒Harada disease (VKHD) is a main type of uveitis in many countries and regions, significantly impacting patient vision. At present, information regarding VKHD is still limited, and further research is needed. We conducted a bibliometric analysis to characterize the overall status, current trends, and current focus of VKHD research.; Literature published from 1975 to 2022 was obtained from the Web of Science core collection and analysed with the R-language packages Bibliometrix, VOSviewer, and CiteSpace software.; A total of 1050 papers on VKHD were retrieved from 261 journals, and 16,084 references were obtained from the papers in the original search. The average annual number of published articles was approximately 21.9, and the number of publications rapidly increased after 2004. The journal Ocular Immunology and Inflammation published the most papers on VKHD, while the American Journal of Ophthalmology has the highest citation frequency. The leading countries were Japan, China (PRC), and the United States of America (USA). Yang PZ from Chongqing Medical University was the most prolific and cited author. The most frequently cited study discussed revision of VKHD diagnostic criteria. An analysis of the highest frequency keywords showed that most research focused on the treatment, diagnosis, and pathogenesis of VKHD and its relationship with other related diseases. At present, the most urgent research direction is in the relationship between COVID-19 or COVID-19 vaccines and VKHD and the corresponding mechanisms underlying it.; Utilizing dynamic and visualization tools, bibliometrics provides a clear depiction of the research history, development trends, and research hotspots in VKHD It serves as a valuable tool for identifying research gaps and areas that necessitate further exploration. Our study revealed potential directions for future VKHD research, including investigating specific molecular mechanisms underlying the disease, exploring the clinical utility of optical coherence tomography angiography and other diagnostic techniques, and conducting clinical research on novel therapeutic drugs.; © 2023. The Author(s).",43,11,4137,4150,Medicine; Bibliometrics; Citation; Web of science; Disease; Coronavirus disease 2019 (COVID-19); China; Science Citation Index; Family medicine; Library science; Pathology; History; Meta-analysis; Infectious disease (medical specialty); Archaeology; Computer science,Bibliometric; H-index; Inflammation; Vogt‒Koyanagi‒Harada disease,Humans; Uveomeningoencephalitic Syndrome/diagnosis; COVID-19 Vaccines; COVID-19; Autoimmune Diseases; Bibliometrics,COVID-19 Vaccines,National Natural Science Foundation of China (81970772); Natural Science Foundation of Tianjin City (21JCZDJC01250); Tianjin Key Medical Discipline (Specialty) Construction Project (TJYXZDXK-016A),https://link.springer.com/content/pdf/10.1007/s10792-023-02815-x.pdf https://doi.org/10.1007/s10792-023-02815-x https://www.researchsquare.com/article/rs-3049460/latest.pdf https://doi.org/10.21203/rs.3.rs-3049460/v1,http://dx.doi.org/10.1007/s10792-023-02815-x,37552428,10.1007/s10792-023-02815-x,,PMC10520158,0,000-442-492-933-294; 000-870-413-246-80X; 002-034-541-103-087; 009-744-719-261-658; 010-550-632-137-961; 012-137-782-868-587; 013-184-825-869-394; 014-126-124-157-715; 014-487-534-552-21X; 014-853-610-266-31X; 015-100-634-549-031; 015-352-262-578-341; 016-683-398-182-525; 018-084-040-407-45X; 018-505-561-788-078; 019-713-293-893-017; 020-960-226-891-357; 022-898-922-244-960; 026-160-596-710-763; 028-304-576-683-588; 028-537-846-142-237; 029-898-684-948-667; 031-086-877-026-595; 032-877-658-419-310; 033-207-215-093-060; 033-674-097-004-807; 033-759-377-734-129; 034-897-901-723-429; 035-023-200-384-427; 035-433-190-364-108; 036-779-033-107-639; 040-138-127-929-398; 040-191-941-733-528; 040-760-639-384-395; 044-076-225-052-539; 045-753-921-020-161; 045-946-258-507-432; 048-763-717-403-42X; 050-464-768-701-218; 051-521-421-928-231; 052-236-888-045-874; 054-074-610-293-017; 062-677-858-386-746; 063-546-584-558-016; 065-517-588-493-088; 066-933-915-205-629; 067-397-577-423-93X; 070-470-033-772-767; 071-255-732-984-763; 072-637-871-893-917; 073-347-124-295-455; 073-539-178-363-851; 077-618-997-304-696; 078-635-859-634-209; 079-150-796-770-545; 080-450-572-870-854; 084-488-662-589-504; 085-598-353-453-359; 087-338-030-132-624; 090-237-366-861-658; 094-717-189-423-267; 096-868-254-559-71X; 097-506-632-441-320; 099-082-844-401-933; 101-858-392-938-224; 103-171-809-199-861; 104-312-210-179-998; 104-816-795-783-590; 107-110-032-099-701; 111-240-966-636-152; 127-638-641-927-489; 133-650-582-251-480; 134-603-418-498-46X; 138-105-497-326-140; 138-466-441-996-368; 139-617-822-195-398; 143-866-705-373-951; 150-525-793-605-238; 165-611-517-845-230; 167-544-539-458-181; 175-923-561-149-211; 188-346-450-373-266,1,true,cc-by,hybrid -123-801-408-482-817,Mapping the entrepreneurship ecosystem scholarship: current state and future directions,2024-05-02,2024,journal article,International Entrepreneurship and Management Journal,15547191; 15551938,Springer Science and Business Media LLC,Germany,Jeffrey Muldoon; Younggeun Lee; Eric W. Liguori; Saumyaranjan Sahoo; Satish Kumar,,20,4,3035,3080,Entrepreneurship; Scholarship; Current (fluid); State (computer science); Ecosystem; Political science; Environmental resource management; Environmental science; Economics; Economic growth; Ecology; Computer science; Engineering; Biology; Electrical engineering; Algorithm; Law,,,,,,http://dx.doi.org/10.1007/s11365-024-00975-5,,10.1007/s11365-024-00975-5,,,0,000-779-767-050-495; 001-710-561-287-949; 002-221-444-730-197; 006-760-028-467-156; 007-226-921-600-112; 008-300-619-248-460; 008-542-441-926-050; 008-799-337-952-324; 008-897-573-867-219; 008-995-700-430-108; 009-007-421-701-622; 010-275-610-749-242; 010-788-610-972-587; 011-473-619-539-085; 012-234-077-072-22X; 013-311-904-762-72X; 013-507-404-965-47X; 014-977-737-822-023; 014-996-083-452-126; 015-098-755-676-90X; 015-485-770-426-896; 016-412-574-900-799; 019-119-561-616-058; 019-968-145-374-471; 020-887-069-227-576; 021-217-796-518-410; 022-531-385-635-075; 022-922-037-080-315; 025-704-347-036-751; 027-487-552-293-284; 027-644-943-215-36X; 028-317-581-588-561; 032-446-061-445-677; 035-189-771-677-178; 035-565-026-132-852; 036-069-783-515-723; 036-174-476-184-172; 037-397-882-557-768; 038-616-494-822-316; 039-517-769-937-087; 040-560-131-598-353; 040-796-863-299-122; 040-983-057-044-030; 043-641-829-647-35X; 044-455-146-997-470; 044-776-532-451-668; 046-922-727-517-474; 046-992-864-415-70X; 047-134-478-431-993; 047-784-432-046-832; 048-250-179-782-392; 055-342-136-376-900; 057-562-057-224-738; 059-159-668-329-304; 060-929-543-111-743; 061-600-047-761-846; 062-219-725-968-461; 063-166-987-720-263; 064-229-089-428-094; 066-498-270-700-660; 066-980-109-481-890; 067-056-711-574-259; 067-115-016-462-690; 068-112-917-509-719; 068-348-198-363-629; 077-699-239-368-671; 078-541-995-528-657; 078-953-445-869-335; 084-026-774-797-731; 084-107-252-799-101; 084-115-375-792-612; 084-238-644-642-031; 084-910-396-000-701; 085-657-106-088-742; 085-856-771-600-680; 089-598-927-192-190; 091-080-588-385-240; 091-417-934-794-575; 092-683-216-793-699; 096-061-214-240-715; 098-294-806-961-743; 098-557-130-254-513; 102-015-798-741-609; 102-071-575-801-615; 102-357-033-648-605; 103-515-124-208-805; 109-163-451-722-977; 112-734-407-598-029; 112-749-486-330-240; 113-682-442-621-962; 114-686-275-444-43X; 115-089-760-187-212; 115-922-623-993-880; 116-442-185-011-341; 117-125-788-981-387; 118-032-859-581-748; 118-810-939-313-59X; 120-489-442-421-53X; 124-037-795-341-349; 125-436-275-173-024; 125-664-350-815-723; 126-348-300-736-084; 128-676-247-501-520; 132-675-363-632-632; 143-051-964-693-346; 146-395-590-725-371; 147-280-546-149-385; 152-169-282-498-586; 152-620-372-579-236; 152-757-061-893-540; 156-302-810-389-064; 157-341-251-662-05X; 158-870-266-734-255; 161-025-712-153-494; 178-668-681-863-587; 179-093-188-602-203; 183-975-680-050-470; 185-270-697-556-817; 197-480-888-321-296,7,false,, -123-966-425-812-22X,Bibliometric Analysis of Wastewater Literature Published in Web of Science 2019 to 2020,2020-11-19,2020,journal article,Library Philosophy and Practice,15220222,University of Idaho Library,United States,Elham Mounir Bador; Isam Mohammad Abdel-Magid; Shakil Ahmad; Mohd Akhter,"The present study used bibliometric and visualization techniques to analyze wastewater literature published in the Web of Science 2019-2020 The bibliometrix tool based on R package, Excel, MS-Access, ScientoPy, and VOS-viewer software packages were used for data analysis and bibliometric indicators extraction This is for evaluating the research productivity of wastewater based on the data collected from documents that covered two recent years The work ventured to examine wastewater researchers' overall performance in their research quest, productivity achievements, and publication accomplishments The study answered questions related to most productive countries, organizations, and authors;preferred types of researcher's sources;authorship collaboration;most frequently used keyword and co-occurrence network in wastewater research;and influential research's citations and usage Likewise, focus concentrated on top-ranked publications, authors per document, degree of collaboration based on the data collected",,,1,21,Engineering; Work (electrical); Productivity; Data science; R package; 2019-20 coronavirus outbreak; Bibliometric analysis; Overall performance; Web of science; Wastewater,,,,,https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=8187&context=libphilprac https://digitalcommons.unl.edu/libphilprac/4529/,https://digitalcommons.unl.edu/libphilprac/4529/,,,3103402742,,0,,0,false,, -124-089-432-634-673,Half a Century of Research for Mind–Body Interventions: A Scientometric Analysis,2025-05-17,2025,journal article,Mindfulness,18688527; 18688535,Springer Science and Business Media LLC,Germany,Michel Sabé; Chaomei Chen; Davy Vancampfort; Joseph Firth; Lee Smith; Brendon Stubbs; Simon Rosenbaum; Felipe Barreto Schuch; Paco Prada; Luigi Francesco Saccaro; Nader Perroud; Camille Piguet; Othman Sentissi; Kerem Böge; Marco Solmi,"Abstract; ; Objectives; We conducted a scientometric analysis on mind–body interventions to assess themes and trends in recent decades, providing insights for prospective research directions. Our systematic search, completed on 1 November, 2023, encompassed the Web of Science Core Collection and focused on scientific publications related to contemplative practices: Mindfulness, Yoga, Qi-gong, Tai-chi, Vipassana, Zen, Loving-kindness, and Transcendental meditation.; ; ; Method; Integration of network analyses and bibliometrics using Bibliometrix and CiteSpace allowed us to identify evolving research themes. Our primary objective was to measure the evolution of research trends, while secondary aims involved uncovering influence networks tied to countries, publications, institutions, and authors. Co-citation reference networks specific to each mind–body practice were extracted.; ; ; Results; Our analysis incorporated 16,310 documents (389,632 references) spanning the years 1973 to 2023, forming a well-structured network with credible clustering. The overarching dataset highlighted the dominance of mindfulness practice in the realm of mind–body interventions. To further explore research patterns, we explored individual co-citation reference networks for each practice, revealing varying sizes for Mindfulness (n = 2278), Yoga (n = 1303), Qi-gong (n = 582), Tai-chi (n = 1000), Vipassana (n = 344), Zen (n = 454), Loving-kindness (n = 552), and Transcendental meditation (n = 834). Each practice exhibited distinct clusters, focusing on applications for diverse mental disorders and physical health issues, ranging from substance abuse to schizophrenia, and from back pain to dementia.; ; ; Conclusions; While research on mind–body interventions has been predominantly influenced by mindfulness in recent decades, each type of mind–body intervention contributes uniquely to both theoretical and clinical contexts. These insights have significant implications for funding agencies and research groups, guiding future directions in the field.; ; ; Preregistration; The preregistered protocol can be found online (https://osf.io/qzb3c/).; ",,,,,Psychology; Psychological intervention; Public health; Mindfulness; Psychotherapist; Applied psychology; Psychiatry; Medicine; Nursing,,,,University of Geneva,,http://dx.doi.org/10.1007/s12671-025-02592-x,,10.1007/s12671-025-02592-x,,,0,000-363-939-413-848; 004-985-841-549-781; 007-669-540-910-566; 007-898-769-775-613; 012-913-829-714-737; 013-507-404-965-47X; 014-322-934-649-218; 015-964-430-763-00X; 016-044-390-307-345; 016-678-838-282-831; 018-206-166-579-364; 018-566-869-114-255; 019-069-839-117-411; 023-841-019-437-52X; 025-180-427-533-358; 027-423-013-331-613; 029-336-020-179-952; 029-420-167-353-195; 034-145-218-792-807; 034-658-158-500-326; 040-580-575-623-36X; 042-249-954-929-687; 044-776-532-451-668; 054-818-565-070-154; 056-517-964-941-635; 058-779-874-212-757; 059-029-632-199-880; 060-230-497-141-60X; 060-390-074-001-106; 062-438-495-949-870; 062-653-882-601-032; 064-400-499-357-900; 067-017-982-632-789; 069-236-387-976-555; 071-945-920-493-521; 072-712-573-142-901; 073-062-993-812-937; 073-400-716-451-159; 076-394-190-151-979; 077-574-219-425-924; 077-632-089-080-800; 079-239-449-715-016; 079-278-714-415-834; 081-349-463-852-905; 085-318-090-383-512; 086-136-489-432-637; 088-496-326-350-137; 089-879-834-755-40X; 090-731-522-534-055; 090-996-812-142-045; 091-934-438-928-410; 104-059-585-039-223; 107-711-465-423-080; 110-563-378-023-51X; 116-317-747-390-548; 118-423-753-745-52X; 118-720-452-546-237; 135-136-520-170-694; 137-763-030-823-395; 155-134-308-450-724; 159-520-087-499-76X; 168-569-061-363-702,0,true,cc-by,hybrid -124-257-591-819-296,A state-of-the-art review on readiness assessment tools in the adoption of renewable energy.,2023-02-02,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Arathy Sudarsan; Chithra Kurukkanari; Deepthi Bendi,,30,12,32214,32229,Renewable energy; Portfolio; Scale (ratio); Systematic review; Field (mathematics); Management science; Environmental economics; Data science; Computer science; Business; Political science; Engineering; Economics; Law; Physics; Mathematics; MEDLINE; Finance; Quantum mechanics; Pure mathematics; Electrical engineering,Alternative energy sources; Assessment tools; Bibliometrix; Literature review; Renewable energy adoption; Transition readiness,Renewable Energy; Energy-Generating Resources; Policy,,,,http://dx.doi.org/10.1007/s11356-023-25520-9,36729221,10.1007/s11356-023-25520-9,,,0,001-279-242-613-211; 002-650-363-829-06X; 006-760-711-809-042; 007-757-798-906-433; 010-062-633-513-217; 013-019-174-054-175; 013-073-019-322-130; 013-507-404-965-47X; 014-794-419-673-294; 016-008-294-807-528; 016-273-192-969-857; 016-621-002-154-031; 016-800-569-578-023; 017-211-277-363-574; 017-445-082-623-083; 018-984-532-738-638; 021-841-018-711-774; 023-037-890-352-271; 023-407-192-708-600; 023-924-024-957-144; 023-978-291-437-139; 032-146-037-086-323; 033-304-193-563-723; 035-638-553-790-560; 038-558-482-068-659; 039-233-327-142-389; 046-036-496-579-638; 048-747-847-726-681; 050-430-667-876-902; 050-788-716-508-169; 055-575-008-251-561; 060-379-453-805-537; 061-577-051-819-948; 062-823-063-132-171; 065-314-317-750-046; 066-636-016-054-168; 066-753-144-333-412; 067-309-687-776-24X; 070-068-493-897-24X; 072-135-202-165-787; 073-552-221-126-031; 074-665-895-561-897; 075-535-258-373-501; 078-354-875-695-967; 081-083-204-897-599; 081-722-415-785-106; 082-807-828-629-581; 084-630-490-512-547; 085-022-053-862-239; 086-303-305-364-541; 088-057-343-403-013; 088-312-594-173-430; 092-298-290-956-096; 100-913-474-855-847; 101-546-605-711-486; 102-108-754-237-534; 102-620-554-156-097; 104-809-306-266-707; 106-470-035-764-052; 107-037-654-123-659; 107-044-757-893-336; 107-363-457-044-023; 116-468-900-528-047; 117-823-936-114-532; 120-309-228-729-049; 120-337-620-615-810; 121-529-391-310-476; 124-069-734-153-463; 128-944-760-000-397; 132-368-551-565-799; 134-799-518-086-726; 135-468-293-524-966; 145-807-904-805-422; 158-971-435-462-119; 162-613-799-709-818; 163-282-962-893-321; 171-511-836-445-700; 177-200-649-232-662,4,false,, -124-689-584-700-341,Research Trend of the Unified Theory of Acceptance and Use of Technology Theory: A Bibliometric Analysis,2021-12-21,2021,journal article,Sustainability,20711050,MDPI AG,Switzerland,Jing Wang; Xinchun Li; Peng Wang; Quanlong Liu; Zhiwen Deng; Jingzhi Wang,"Information technology-acceptance research has always been a research hotspot. In 2003, Venkatesh established the unified theory of acceptance and use of technology (UTAUT), which pushed information technology-acceptance research to a new climax. This study uses bibliometrics, Bibliometrix, and CiteSpace software to conduct data mining and quantitative analysis on 1694 research papers in the UTAUT in the Web of Science core collection database from 2003 to 2021 (the data update time is 13 August 2021). Combined with a visual bibliometric analysis, this paper makes an in-depth discussion on the UTAUT model from the aspects of research trends, research fields, main research journals, authors/institutions, national or regional cooperation networks, etc. This study comprehensively and systematically shows the evolution track and characteristics of the UTAUT. On this basis, the future development trend of the UTAUT is put forward.",14,1,10,10,Bibliometrics; Unified theory of acceptance and use of technology; Computer science; Data science; Information technology; Management science; Data mining; Engineering; Social science; Sociology; Social influence; Operating system,,,,the Fundamental Research Funds for the Central Universities,https://www.mdpi.com/2071-1050/14/1/10/pdf?version=1640076898 https://doi.org/10.3390/su14010010,http://dx.doi.org/10.3390/su14010010,,10.3390/su14010010,,,0,001-210-600-856-85X; 001-939-984-590-654; 003-027-205-062-889; 003-653-621-055-547; 004-764-715-271-126; 007-475-955-444-16X; 007-898-589-255-610; 008-136-049-523-501; 009-161-356-961-246; 013-507-404-965-47X; 015-131-912-189-833; 015-707-707-099-520; 019-087-175-529-008; 020-156-537-824-496; 024-133-097-258-227; 029-225-530-165-452; 029-896-107-086-391; 030-014-892-430-810; 030-553-205-069-182; 032-906-465-376-131; 033-665-693-191-608; 034-375-813-423-508; 038-496-110-547-586; 039-488-066-669-338; 042-036-771-298-967; 042-277-409-510-854; 044-041-213-086-125; 044-944-587-598-86X; 045-532-883-557-654; 051-051-819-846-048; 051-734-558-399-018; 058-081-424-637-980; 064-400-499-357-900; 066-790-307-377-472; 076-319-339-449-539; 077-574-649-270-854; 086-247-992-544-427; 095-926-768-457-602; 109-844-820-383-637; 110-248-254-371-15X; 117-137-754-620-717; 120-609-308-092-61X; 124-288-751-266-822; 125-782-585-065-012; 130-501-471-726-916; 134-692-988-441-892; 138-080-639-598-099; 138-148-971-699-156; 143-875-130-007-110; 149-112-858-264-550; 152-565-141-046-396; 165-967-694-898-584; 176-118-402-188-496; 179-248-911-785-461,30,true,cc-by,gold -124-978-996-449-043,Exploring Literature on Financial Socialization – A Bibliometric Analysis,2023-11-27,2023,journal article,TEM Journal,22178333; 22178309,Association for Information Communication Technology Education and Science (UIKTEN),,Souparnna Lakshmi Parthasarathy; Vidhya Vinayachandran,"In the past few years, extensive research has focused on comprehending the influence of financial socialization on people's financial habits and overall welfare, indicating a substantial convergence in the area. This article bases itself on a review of literature of prior research, using selected keywords to search the SCOPUS database. Further, the Bibliometrix R package was utilized for the analysis to ensure comprehensive results. The significant themes identified are public attitude, financial system, sustainability, and financial education. The present research sheds light on the growing importance of financial socialization and its various domains which is yet to be explored by theoreticians and practitioners from various countries.",,,2295,2304,Socialization; Scopus; Financial literacy; Finance; Political science; Business; Sociology; Social science; MEDLINE; Law,,,,,https://www.temjournal.com/content/124/TEMJournalNovember2023_2295_2304.pdf https://doi.org/10.18421/tem124-40,http://dx.doi.org/10.18421/tem124-40,,10.18421/tem124-40,,,0,,0,true,cc-by-nc-nd,gold -125-446-881-932-624,INNOVATION AND RESILIENT DESTINATIONS: A LITERATURE REVIEW,2023-05-12,2023,conference proceedings article,"International Scientific Conference ""Business and Management""",2029929x; 20294441,Vilnius Gediminas Technical University,,Simone Luongo; Eleonora Napolano; Fabiana Sepe; Giovanna Del Gaudio,"This study aims to advance knowledge on innovation processes and destination resilience in the post-pandemic world, adopting a systematic literature review through Bibliometrix software. Based on an abductive analysis, this work shows the findings of peer-reviewed studies published in leading hospitality and tourism journals between 2005 and 2023. The data was subjected to thematic analysis and clustered under five main categories based on the distribution of articles by publication year, research topic, author contributions, articles by journal, and articles by country. The original value of this study lies on the identification of innovation forces able to enhance destination resilience.",,,,,Hospitality; Destinations; Tourism; Thematic analysis; Resilience (materials science); Identification (biology); Work (physics); Data science; Value (mathematics); Psychological resilience; Knowledge management; Computer science; Sociology; Qualitative research; Geography; Engineering; Psychology; Social science; Mechanical engineering; Physics; Botany; Archaeology; Machine learning; Biology; Psychotherapist; Thermodynamics,,,,,http://www.bm.vgtu.lt/index.php/verslas/2023/paper/download/1054/589 https://doi.org/10.3846/bm.2023.1054,http://dx.doi.org/10.3846/bm.2023.1054,,10.3846/bm.2023.1054,,,0,000-778-552-099-596; 001-884-891-952-358; 004-200-862-089-160; 010-669-153-225-751; 013-248-302-306-429; 013-497-328-534-240; 013-507-404-965-47X; 013-679-449-013-836; 013-918-676-206-991; 015-489-546-136-665; 017-492-912-498-771; 022-268-802-854-418; 028-541-174-278-79X; 030-649-113-805-505; 031-279-725-265-82X; 034-000-215-203-846; 038-685-900-117-559; 038-869-414-289-589; 041-350-246-578-775; 041-574-024-925-754; 046-837-763-656-74X; 046-992-864-415-70X; 047-739-163-843-434; 049-062-601-267-141; 050-318-237-958-211; 058-764-875-376-292; 070-439-461-846-632; 071-197-166-431-984; 072-067-405-816-007; 076-296-003-426-772; 077-135-643-979-665; 079-900-894-417-251; 081-514-643-896-274; 084-447-152-259-141; 087-083-656-682-829; 092-208-772-056-996; 092-245-947-795-882; 093-041-056-362-129; 093-119-883-182-444; 095-275-636-460-918; 110-506-073-059-65X; 123-220-032-583-074; 129-300-941-888-148; 137-907-190-339-199; 144-400-047-271-727; 152-420-184-690-109; 170-307-020-954-196; 173-055-298-268-482; 182-723-855-324-561,0,true,cc-by,hybrid -125-717-394-117-181,Escaneo científico sobre tendencias en agroindustria,,2024,report,,,Corporación colombiana de investigación agropecuaria - AGROSAVIA,,Alexis Morales Castañeda; Carlos Alberto Contreras Pedraza,"La agroindustria enfrenta desafíos crecientes relacionados con el cambio climático, la seguridad alimentaria y la sostenibilidad, lo que ha impulsado investigaciones orientadas a la innovación tecnológica. Este análisis, basado en 18.121 publicaciones científicas indexadas en Scopus® (2020–2024), identifica tendencias clave en conservación postcosecha, biotecnología y aprovechamiento sostenible de residuos agrícolas, mediante herramientas cienciométricas como Bibliometrix® y VOSviewer®, que permiten mapear tópicos relevantes y clústeres de investigación en este sector estratégico.",,,,,,,,,,,http://dx.doi.org/10.21930/agrosavia.escaneocientifico.2024.4,,10.21930/agrosavia.escaneocientifico.2024.4,,,0,,0,false,, -125-834-927-566-661,Bibliometrix applied to computational simulation for wind generator,2024-12-26,2024,journal article,Latin American Journal of Energy Research,23582286,Latin American Journal of Energy Research,,Tainan Viana; Alexandre Sales Costa; Lara Albuquerque Fortes; Carla Freitas de Andrade; Francisco Olímpio Moura Carneiro; Mona Lisa Moura de Oliveira,"This study presents a comprehensive bibliometric analysis of computational simulations in wind turbine projects, addressing their pivotal role amid growing demands for renewable energy and engineering project optimization. The primary objective is to discern trends, focal areas, and global collaboration networks.Utilizing Scopus and Web of Science databases, supported by CAPES, all pertinent publications on computational simulations in wind turbine projects were scrutinized. Bibliometric metrics were analyzed using the bibliometrix library in R.Findings reveal a increase in publications since 2022, particularly in aerodynamic optimization and offshore projects. Leading contributors are universities, research centers across Europe, North America, and prominently China. Co-authorship networks underscore significant collaborations among global academic institutions. Key terms such as ""computational modeling,"" ""CFD (Computational Fluid Dynamics),"" and ""wind turbine"" predominate in literature.The analysis confirms the escalating significance of computational simulations in wind turbine projects, underscored by burgeoning publications and international partnerships. Integration of emerging technologies like artificial intelligence and machine learning into market practices is evident. This study serves as a foundational resource for future researchers and industry stakeholders, identifying promising avenues and areas necessitating further exploration.",11,2,119,134,Generator (circuit theory); Wind generator; Computer science; Wind power; Environmental science; Electrical engineering; Engineering; Physics; Power (physics); Quantum mechanics,,,,,,http://dx.doi.org/10.21712/lajer.2024.v11.n2.p119-134,,10.21712/lajer.2024.v11.n2.p119-134,,,0,000-040-093-987-330; 001-014-155-427-054; 002-525-206-240-734; 006-937-464-876-205; 008-624-665-493-871; 009-189-057-134-86X; 013-507-404-965-47X; 016-141-918-036-745; 016-851-118-201-331; 017-355-332-357-576; 019-100-713-946-532; 019-993-363-116-483; 021-106-232-876-931; 023-430-370-878-625; 025-396-447-858-46X; 027-182-047-861-001; 030-472-928-227-207; 033-028-264-176-299; 033-847-397-030-081; 038-066-361-097-778; 039-089-220-773-304; 041-616-718-183-559; 043-508-390-930-411; 043-561-886-617-384; 044-144-049-367-380; 046-992-864-415-70X; 048-739-848-298-113; 055-472-900-053-193; 056-328-675-248-671; 058-843-246-440-795; 059-036-347-807-475; 063-101-316-120-147; 065-607-862-009-244; 066-989-725-067-862; 067-234-166-824-177; 068-875-734-537-704; 069-966-011-820-047; 072-749-334-385-673; 078-035-744-662-622; 078-593-787-410-579; 080-018-838-027-782; 080-401-671-327-952; 081-955-516-281-65X; 083-816-555-345-655; 087-899-496-303-050; 087-920-458-761-732; 089-719-068-750-77X; 093-551-908-293-216; 096-187-362-122-669; 100-144-811-177-888; 100-646-312-633-367; 101-846-614-880-147; 103-349-139-840-423; 108-839-036-193-765; 110-216-215-735-970; 118-272-430-254-237; 142-090-199-291-061; 143-768-688-601-844; 145-813-469-590-05X; 155-588-841-904-786; 160-957-113-306-915; 162-616-607-994-233; 175-429-461-075-08X; 187-849-278-569-053; 189-210-431-972-718; 195-946-577-374-058; 198-937-578-126-763,0,true,,gold -125-892-584-771-49X,A Bibliometric Analysis of Social Media and Election Campaign Success: Mapping Research Trends from 2019 to 2023,2025-06-24,2025,journal article,INJECT (Interdisciplinary Journal of Communication),25487124; 25485857,IAIN Salatiga,,Nurul Wahdaniyah; Dian Eka Rahmawati; Inrinofita Sari,"This paper aims to identify trends and research mapping on the Influence of social media on the Success of Election Campaigns that have concerned academics and practitioners. The method used in this research is qualitative research with a literature study approach. The data found were 258 documents, which were then analyzed. This dataset was converted to CSV format, imported into Bibliometrix, and analyzed. The findings in this study show that the success of election campaigns is not only related to social media factors but also to the successful integration of various strategic elements in the political process. Social media platforms, including Twitter, Facebook, YouTube, and Telegram, are the main channels for delivering political messages directly to voters. This success also depends on the capacity of candidates or political parties to utilize social media effectively.",10,1,407,426,,,,,,,http://dx.doi.org/10.18326/inject.v10i1.4439,,10.18326/inject.v10i1.4439,,,0,,0,false,, -126-116-384-129-691,Education and Business in Conditions of Coopetition: Bibliometrics,,2022,journal article,Business Ethics and Leadership,25206311; 25206761,Academic Research and Publishing U.G.,,Vitaliia Koibichuk; Anastasiia Samoilikova; Valeriia Herasymenko,"The study of the relationship between education and business is a very relevant issue when education and business are key factors in developing and uplifting the economy. Education is the foundation for creating a business since the effective activity is impossible without a strong information base. The purpose of this research is a bibliographic review of scientific publications devoted to the relationship between business and education, based on materials indexed by the Scopus, Web of Science, and Mendeley databases using the built-in functions of the Bibliometrix application and the R programming language. The logic of the research is implemented with the help of three stages: at the first stage, an analysis of literary sources related to bibliometric analysis, as well as about business and education, the interdependence of education and business, which were published in the publishing house of MDPI scientific journals with open access, was carried out. Survey and interview methods are the methodological tools of most of the analyzed publications in the open access of the MDPI database. The research is conducted in the R language, using VOSViewer tools for bibliometric analysis. Various qualitative and quantitative methods were used to analyze the relationship between education and business, such as performance analysis, scientific mapping and thematic analysis, structural equation modelling, and Z-score statistics. At the second stage, the main functions of the Bibliometrix package were studied, countries, keywords constructed a three-field plot, and the year of publication of cited references to reflect the proportion of research topics for each country and the freshness of cited articles. Source clustering through Bradford’s Law was also used to identify the best journals for publishing own research and searching for the most relevant scientific information. In addition, the Hirsch and Gini indexes of the selected sample of publications were examined in detail within the second stage. The Hirsch index is a quantitative measure of productivity based on analyzing published publications and citations. The distribution of authorship is estimated using the Gini index. At the third stage, keywords were analyzed, and a table was built with the most frequently used words to decrease the number of keywords mentioned. The conducted comprehensive analysis of scientific publications confirmed the close correlation of paradigms of business and education in the conditions of coopetition in modernity.",6,4,49,60,Scopus; Computer science; Bibliometrics; Field (mathematics); Publishing; Knowledge management; Data science; Library science; Political science; Mathematics; MEDLINE; Pure mathematics; Law,,,,,https://armgpublishing.com/wp-content/uploads/2023/01/BEL_4_2022_5.pdf https://doi.org/10.21272/bel.6(4).49-60.2022,http://dx.doi.org/10.21272/bel.6(4).49-60.2022,,10.21272/bel.6(4).49-60.2022,,,0,002-592-665-696-765; 007-206-754-521-813; 013-507-404-965-47X; 020-196-220-205-001; 086-841-776-723-721; 087-698-591-446-382; 088-577-115-503-054; 107-549-688-291-73X; 111-088-248-024-721; 132-116-966-608-382; 146-568-411-116-662; 170-195-756-439-943; 183-791-301-288-918,7,true,cc-by,gold -126-334-427-301-486,The pyroptosis and fibrotic diseases: a bibliometric analysis from 2010 to 2024.,2024-11-13,2024,journal article,Systematic reviews,20464053,Springer Science and Business Media LLC,United Kingdom,Long Zhu; Lijia Ou; Binjie Liu; Yang Yang; Chang Su; Ousheng Liu; Hui Feng,"Fibrosis is the ultimate, common pathological ending of most chronic inflammatory diseases and increases the chances of developing life-threatening illnesses. Pyroptosis, a newfound form of lytic programmed cell death initiated by the inflammasome, has received more and more attention because of its association with fibrotic diseases. Therefore, this study visualizes the connection between pyroptosis and fibrosis research through bibliometric methods, aimed at providing global research hits and tendencies in the field.; We collected and analyzed the articles on pyroptosis and fibrosis from 2010 to 2024 via Web of Science. Visual data analysis was performed for countries, institutions, authors, references, and keywords in the field using VOSviewer, CiteSpace software, the ""Bibliometrix"" R package, the bibliometric website ( https://bibliometric.com/ ), and Excel software. We analyzed the data by utilizing the bibliometric review method.; A total of 566 articles and reviews relating to pyroptosis and fibrosis were identified in the Web of Science. The number of publications in the domain has continued to grow since 2010. These scientific outputs were mainly from 129 countries/regions and 1919 institutions, particularly China (n = 423) and the USA (n = 83). More importantly, although China publishes a vast majority of articles, its centrality is lower than that of the USA (0.59 vs 0.61). Among the 3833 authors involved in this field, Feldstein, A. E. is the most prolific author. Shi, J. J. is the world's most-cited author among the 12,143 authors in these academic journals. Frontiers in Immunology was a prolific contributor, and Nature was the most frequently cited journal. After analysis, Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death were the top-cited articles. The analysis of keywords displayed that pyroptosis, fibrosis, and pathways were the main research hotspots and frontier directions in recent years.; We analyzed the characteristics of published articles and drew a fundamental knowledge structure on pyroptosis and fibrosis research via bibliometric analysis. The potential mechanism between fibrosis and pyroptosis is deeply tied to the current moment. Our findings can help researchers make clear the research status and value of fibrosis and pyroptosis and provide new directions for future research as soon as possible.; © 2024. The Author(s).",13,1,279,,Medicine; Pyroptosis; Environmental health; Internal medicine; Inflammasome; Inflammation,,Pyroptosis; Bibliometrics; Humans; Fibrosis,,,,http://dx.doi.org/10.1186/s13643-024-02703-0,39538318,10.1186/s13643-024-02703-0,,PMC11562867,0,000-353-355-353-90X; 004-953-114-154-488; 006-115-231-622-447; 006-842-435-718-775; 007-645-964-839-402; 010-203-555-734-220; 011-301-822-302-672; 013-507-404-965-47X; 013-575-069-546-730; 015-023-100-024-752; 015-545-639-911-230; 017-150-060-168-237; 019-768-814-709-667; 022-878-418-236-373; 025-873-249-777-561; 026-234-769-587-441; 030-459-268-464-883; 031-415-977-230-280; 033-095-593-279-897; 038-490-702-920-113; 040-189-460-713-03X; 041-713-639-438-925; 043-841-350-393-016; 044-788-977-218-867; 044-888-205-712-142; 048-227-442-127-585; 056-476-751-903-303; 057-917-816-442-980; 062-803-225-690-670; 063-577-848-292-680; 073-898-591-853-381; 074-102-678-320-692; 076-357-938-093-930; 080-977-108-232-315; 081-667-601-846-241; 083-031-239-299-925; 083-497-498-597-083; 087-453-871-787-629; 089-950-113-895-743; 090-476-872-676-699; 094-542-112-122-640; 096-846-605-600-706; 102-070-620-293-193; 107-191-743-907-952; 111-869-633-387-168; 118-317-668-303-891; 119-280-925-345-305; 123-218-689-488-554; 124-858-978-191-003; 137-857-714-516-852; 142-947-524-322-096; 150-023-754-670-993; 161-172-042-390-131; 166-079-115-077-695; 190-957-439-441-664,0,true,"CC BY, CC0",gold -126-631-175-365-133,Progress and evolution of hotspots in butterfly diversity research in green spaces.,2024-02-13,2024,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Ying Lin; Shanjun Huang; Wenqiang Fang; Shiyuan Fan; Chengyu Ran; Emily Dang; Weicong Fu; Zhipeng Zhu,,32,6,3147,3159,Butterfly; Biodiversity; Geography; Diversity (politics); Habitat; Ecology; Environmental resource management; Biology; Sociology; Environmental science; Anthropology,Biodiversity conservation; Butterfly diversity; CiteSpace; Green space; Quantitative analysis,Butterflies; Biodiversity; Animals; Ecosystem; Conservation of Natural Resources,,"Green Urbanization across China and Europe: Collaborative Research on Key technological Advances in Urban Forests (2021YFE0193200); Horizon 2020 strategic plan: CLEARING HOUSE-Collaborative Learning in Research, Information sharing, and Governance on How Urban tree-based solutions support Sino-European urban futures (821242); National Non-Profit Research Institutions of the Chinese Academy of Forestry (CAFYBB2020ZB008)",,http://dx.doi.org/10.1007/s11356-024-32269-2,38347362,10.1007/s11356-024-32269-2,,,0,002-162-070-975-941; 003-201-959-470-572; 003-817-603-324-254; 010-028-119-247-906; 010-114-265-608-360; 011-177-120-818-601; 013-507-404-965-47X; 014-019-138-997-666; 019-355-665-347-475; 029-327-744-434-256; 030-296-199-128-718; 031-094-771-196-289; 033-248-413-039-314; 040-014-758-319-284; 040-632-278-136-268; 041-959-215-630-278; 046-426-018-074-065; 050-580-947-928-66X; 051-856-815-127-896; 054-152-584-058-697; 054-374-438-282-002; 057-975-238-464-744; 064-482-912-103-288; 065-687-321-113-981; 069-511-868-544-95X; 070-670-824-482-690; 072-658-670-632-342; 074-562-775-743-82X; 078-071-506-272-504; 078-164-280-579-652; 084-026-774-797-731; 092-710-855-786-939; 100-240-948-968-154; 100-952-140-417-339; 101-849-902-109-334; 102-910-096-010-335; 107-349-103-644-514; 108-838-812-821-062; 114-507-544-289-292; 115-268-501-173-717; 116-902-212-594-058; 120-974-286-046-262; 139-372-220-868-505; 148-394-379-407-966; 168-637-893-447-29X; 171-070-670-027-54X; 180-836-146-425-835; 183-891-112-474-445,2,false,, -127-105-240-087-640,PREDITORES DE BURNOUT EM ENFERMEIRO(A)S: DESCOBERTAS E REFLEXÕES A PARTIR DE UM ESTUDO BIBLIOMÉTRICO,,2022,journal article,Revista SODEBRAS,18093957,Revista SODEBRAS,,S. C. Fernandes; V. H. A. Souza,"The professional nurse, when dealing with a patient, often experiences adverse situations in their work environment. This can affect their health. In order to know about this daily life, the present study aimed to carry out a bibliometric analysis on the theme Burnout in nurses where, in a more punctual way, we sought to identify the main predictors of Burnout of this profession from recent international publications. In the first part of the study, the software R (bibliometrix package) was used. Burnout predictors were identified from the articles resulting from the bibliometric search. The survey results pointed to an increase in publications over the years with a peak in 2018. The largest contributions in quantitative terms are still from the United States of America. Burnout predictors have an organizational and relational origin. Individual aspects, such as resilience, appear in a relevant way to avoid professional illness.",17,197,8,18,Humanities; Physics; Political science; Philosophy,,,,,,http://dx.doi.org/10.29367/issn.1809-3957.17.2022.197.08,,10.29367/issn.1809-3957.17.2022.197.08,,,0,,0,true,,gold -127-513-920-910-293,"Two decades of research on ocean multi-use: achievements, challenges and the need for transdisciplinarity",2024-02-18,2024,journal article,npj Ocean Sustainability,2731426x,Springer Science and Business Media LLC,,Josselin Guyot-Téphany; Brice Trouillet; Sereno Diederichsen; Elea Juell-Skielse; Jean-Baptiste E Thomas; Jennifer McCann; Céline Rebours; Marinez Scherer; Peter Freeman; Fredrik Gröndahl; John Patrick Walsh; Ivana Lukic,"AbstractThis paper offers a comprehensive, analytical, and critically informed overview of the current state of ocean multi-use research. It delves into the origins, trajectory, and driving forces behind this emerging research field, all within the broader context of investigations addressing the management of increasingly diverse and intensifying activities at sea. The Bibliometrix R package is employed to analyze the social, geographical, and conceptual dimensions of multi-use scientific production. The results obtained are then compared to a larger corpus of publications focusing on both multiple-use Marine Protected Areas (MPAs) and Marine Spatial Planning (MSP). Finally, the paper addresses research gaps, with a particular emphasis on the transdisciplinary challenges associated with translating this new marine policy concept into practical implementation and extending its application beyond European seas.",3,1,,,Transdisciplinarity; Environmental planning; Regional science; Environmental resource management; Geography; Environmental science; Sociology; Social science,,,,,https://www.nature.com/articles/s44183-024-00043-z.pdf https://doi.org/10.1038/s44183-024-00043-z,http://dx.doi.org/10.1038/s44183-024-00043-z,,10.1038/s44183-024-00043-z,,,0,001-046-988-405-243; 001-251-619-608-136; 002-609-021-833-662; 003-353-060-853-674; 003-725-733-261-695; 004-421-216-940-36X; 005-573-258-349-876; 005-771-965-152-754; 006-011-313-372-158; 006-441-595-987-694; 009-591-390-984-708; 010-964-993-188-30X; 012-672-456-676-912; 012-928-213-794-988; 013-507-404-965-47X; 014-253-242-908-446; 017-423-130-656-473; 018-923-055-959-34X; 019-289-780-192-787; 021-864-078-151-248; 022-424-248-591-623; 027-366-566-566-457; 027-687-919-417-252; 027-977-584-292-528; 031-600-025-202-981; 033-516-086-560-652; 034-105-307-714-53X; 037-730-591-990-664; 039-981-140-297-042; 040-524-235-051-290; 046-189-071-735-911; 046-333-224-742-770; 046-605-236-069-049; 047-724-750-351-600; 050-340-687-668-052; 058-525-898-816-766; 063-121-827-929-050; 063-332-431-168-654; 063-974-571-099-800; 066-067-226-447-501; 067-068-078-755-369; 070-009-124-421-57X; 071-886-051-781-988; 072-191-025-024-962; 076-020-559-167-641; 077-640-728-393-310; 078-402-149-710-951; 078-848-798-571-310; 081-721-278-486-278; 082-020-142-011-753; 083-137-749-916-634; 083-874-580-417-062; 089-908-459-328-288; 091-792-370-998-373; 092-808-324-371-713; 093-297-383-821-31X; 093-307-037-899-305; 095-489-672-940-568; 095-600-488-507-126; 096-763-136-385-295; 097-637-398-247-65X; 098-377-939-800-955; 101-392-203-896-044; 105-720-649-434-202; 107-573-170-970-56X; 107-912-914-473-851; 109-099-396-556-756; 112-538-571-948-205; 114-420-450-852-783; 119-058-477-051-831; 119-114-459-841-403; 119-294-923-202-375; 120-527-588-592-117; 126-510-365-093-879; 127-673-713-067-574; 128-027-310-235-959; 130-783-948-723-404; 133-694-383-287-784; 135-966-232-517-06X; 137-641-959-702-28X; 139-277-300-552-767; 142-627-418-836-998; 146-703-745-491-939; 154-770-372-522-893; 156-529-809-083-259; 161-541-342-396-536; 162-435-837-100-431; 163-175-368-818-94X; 165-735-533-656-768; 187-966-581-766-52X,12,true,cc-by,gold -127-621-586-673-760,A bibliometric study on recent trends in artificial intelligence-based suspicious activity recognition,2023-05-27,2023,journal article,Security Journal,09551662; 17434645,Springer Science and Business Media LLC,United States,Zouheir Trabelsi; Medha Mohan Ambali Parambil,,37,2,399,424,Scopus; General partnership; Computer science; Data science; Field (mathematics); Bibliometrics; Bibliographic coupling; Automatic summarization; Citation; Tag cloud; Artificial intelligence; World Wide Web; Visualization; Political science; Mathematics; MEDLINE; Pure mathematics; Law,,,,United Arab Emirates University; United Arab Emirates University,,http://dx.doi.org/10.1057/s41284-023-00382-5,,10.1057/s41284-023-00382-5,,,0,002-052-422-936-00X; 013-507-404-965-47X; 027-349-974-624-404; 033-344-451-183-499; 050-747-936-075-288; 064-400-499-357-900; 071-035-632-063-735; 079-050-236-131-309; 079-689-690-946-169; 093-341-563-313-561; 152-554-691-890-168; 185-421-860-898-573,1,false,, -127-709-616-111-571,EL EMPRENDIMIENTO TURÍSTICO RURAL Y SUS TENDENCIAS A TRAVÉS DE UN ANÁLISIS BIBLIOMÉTRICO,2024-06-28,2024,journal article,Cuadernos de Turismo,19894635; 11397861,Servicio de Publicaciones de la Universidad de Murcia,Spain,Gabith Miriam Quispe Fernández; José Manuel Jurado Almonte; Dante Ayaviri Nina,"This research carries out a bibliometric analysis of rural tourism entrepreneurship with the aim of understanding the research carried out. The analysis covers the period 2002-2022 and uses the Scopus indexing database. It includes scientific articles, conference contributions and book chapters published in English and Spanish. The tools used for this analysis were Bibliometrix and VOSviewer. The conclusions show a sustained growth in scientific production and the existence of important countries involved in this subject. Trends in tourism entrepreneurship are focused on local development, sustainability of rural tourism enterprises and human and social capital.; Esta investigación realiza un análisis bibliométrico del emprendimiento turístico rural con el objetivo de conocer la investigación desarrollada. El análisis contempla el periodo 2002-2022 y emplea la base de datos de indexación Scopus. Contempla artículos científicos, aportaciones de conferencias y capítulos de libros publicados en inglés y español. Las herramientas que permitieron realizar este análisis fueron Bibliometrix y VOSviewer. Las conclusiones muestran un crecimiento sostenido de la producción científica y la existencia de importantes países involucrados en esta temática. Las tendencias en la actividad emprendedora turística están centradas en el desarrollo local, la sostenibilidad de los emprendimientos turísticos rurales y el capital humano y social.",,53,69,93,Political science; Regional science; Geography,,,,,https://rabida.uhu.es/dspace/bitstream/10272/23979/2/04-Cuadernos%20de%20Turimo%2c%2053.pdf https://hdl.handle.net/10272/23979,http://dx.doi.org/10.6018/turismo.616391,,10.6018/turismo.616391,,,0,,0,true,cc-by-nc-nd,gold -127-842-323-552-392,An analysis of meiofauna knowledge generated by Latin American researchers,2022-11-17,2022,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Bernardo Baldeija; Diego Lercari,"Bibliographic databases used to analyse the document production of benthic meiofauna in Latin American countries. To be opened on R, bibliometrix package.",,,,,Meiobenthos; Latin Americans; Oceanography; Geography; Data science; Environmental science; Computer science; Geology; Political science; Benthic zone; Law,,,,,https://zenodo.org/record/7331760,http://dx.doi.org/10.5281/zenodo.7331760,,10.5281/zenodo.7331760,,,0,,0,true,cc-by,gold -128-066-307-029-507,A scientometric analysis of the effect of COVID-19 on the spread of research outputs,2023-09-23,2023,journal article,Quality & Quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Gianpaolo Zammarchi; Andrea Carta; Silvia Columbu; Luca Frigau; Monica Musio,"AbstractThe spread of the COVID-19 pandemic in 2020 had a huge impact on the life course of all of us. This rapid spread has also caused an increase in the research production in topics related to different aspects of COVID-19. Italy has been one of the first countries to be massively involved in the outbreak of the disease. In this paper, we present an extensive scientometric analysis of the research production both at global (entire literature produced in the first 2 years after the beginning of the pandemic) and local level (COVID-19 literature produced by authors with an Italian affiliation). Our results showed that US and China are the most active countries in terms of number of publications and that the number of collaborations between institutions varies depending on geographical distance. Moreover, we identified the medical-biological as the field with the greatest growth in terms of literature production. As regards the analysis focused on Italy, we have shown that most of the collaborations follow a geographical pattern, both externally (with a preference for European countries) and internally (two clusters of institutions, north versus center-south). Furthermore, we explored the relationship between the number of citations and variables obtained from the data set (e.g. number of authors). Using multiple correspondence analysis and quantile regression we shed light on the role of journal topics and impact factor, the type of article, the field of study and how these elements affect citations.",58,3,2265,2287,Coronavirus disease 2019 (COVID-19); Regional science; Pandemic; China; Quantile regression; Geography; Field (mathematics); Preference; Economic geography; Outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Impact factor; Production (economics); Econometrics; Statistics; Political science; Economics; Disease; Mathematics; Medicine; Infectious disease (medical specialty); Archaeology; Pathology; Virology; Pure mathematics; Law; Macroeconomics,,,,Fondazione di Sardegna; Università degli Studi di Cagliari,https://link.springer.com/content/pdf/10.1007/s11135-023-01742-4.pdf https://doi.org/10.1007/s11135-023-01742-4,http://dx.doi.org/10.1007/s11135-023-01742-4,,10.1007/s11135-023-01742-4,,,0,001-606-202-274-636; 004-199-688-892-138; 004-611-609-458-598; 005-276-917-136-778; 008-329-649-073-373; 010-775-454-374-784; 013-507-404-965-47X; 013-962-954-687-771; 014-904-298-227-056; 015-857-923-685-296; 016-653-244-253-995; 018-559-221-080-181; 026-501-432-015-935; 028-649-560-988-76X; 030-070-985-228-781; 038-633-592-158-230; 041-141-636-101-701; 042-229-634-189-386; 049-210-365-290-957; 054-913-539-162-480; 054-979-714-187-936; 063-789-423-782-849; 065-913-003-281-798; 067-263-492-957-015; 078-552-591-516-602; 082-406-922-825-952; 082-612-298-781-34X; 095-534-262-006-772; 107-518-655-388-824; 108-325-327-295-974; 111-996-636-948-305; 130-557-115-034-027; 134-651-626-151-387; 148-493-161-692-251; 181-953-131-517-867,4,true,cc-by,hybrid -128-100-581-455-505,A bibliometric analysis of revenue management in airline industry,2020-05-06,2020,journal article,Journal of Revenue and Pricing Management,14766930; 1477657x,Springer Science and Business Media LLC,United Kingdom,Syed Asif Raza; Rafi Ashrafi; Ali Akgunduz,,19,6,436,465,Business; Bibliometrics; Systematic review; Co-citation; Revenue management; Bibliometric analysis; Field (computer science); Strategic planning; Knowledge management; Identification (information),,,,,https://ideas.repec.org/a/pal/jorapm/v19y2020i6d10.1057_s41272-020-00247-1.html https://link.springer.com/article/10.1057/s41272-020-00247-1,http://dx.doi.org/10.1057/s41272-020-00247-1,,10.1057/s41272-020-00247-1,3022215423,,0,001-326-942-471-575; 001-634-912-247-93X; 002-052-422-936-00X; 002-558-780-058-428; 002-835-920-919-289; 003-138-491-331-227; 003-177-390-516-54X; 003-956-547-496-288; 005-982-822-033-555; 006-020-140-039-844; 006-066-000-217-323; 007-335-769-320-919; 007-995-315-851-823; 008-822-263-503-27X; 008-888-172-446-793; 008-971-130-579-093; 009-717-071-806-921; 011-137-429-936-239; 011-364-541-838-073; 011-476-919-937-994; 011-859-453-708-855; 012-140-970-151-257; 012-832-601-785-905; 013-507-404-965-47X; 013-524-854-219-241; 016-854-012-679-998; 018-475-134-276-620; 019-607-643-064-659; 019-786-947-568-596; 020-120-865-235-418; 023-670-406-543-281; 023-927-221-065-800; 024-489-561-684-615; 024-941-525-914-506; 024-976-002-707-102; 025-825-970-424-255; 026-450-606-469-359; 029-004-736-470-517; 029-225-228-986-006; 029-286-730-940-491; 030-825-258-828-011; 031-684-290-967-900; 034-403-930-467-070; 034-647-677-050-044; 035-407-289-573-402; 035-494-531-596-791; 038-305-529-793-28X; 039-538-433-742-30X; 039-876-873-409-000; 042-474-047-254-816; 042-519-224-297-080; 043-725-124-797-110; 044-887-492-598-789; 044-968-153-657-70X; 045-947-660-131-87X; 046-258-727-781-993; 047-134-478-431-993; 047-406-998-453-164; 050-967-917-534-885; 051-284-643-440-382; 052-415-088-159-850; 053-598-695-896-482; 054-651-512-571-877; 054-818-565-070-154; 055-106-982-626-943; 055-222-575-590-371; 055-277-481-388-154; 055-996-089-769-64X; 056-470-247-369-597; 057-058-693-769-402; 057-948-688-793-429; 058-100-283-244-876; 058-264-021-351-517; 058-989-762-188-102; 061-295-142-491-102; 062-553-965-326-445; 064-860-426-646-979; 068-427-844-412-487; 068-434-171-569-839; 069-743-299-158-532; 069-811-881-086-29X; 070-991-282-066-330; 072-627-934-597-674; 074-205-235-631-346; 074-412-397-558-18X; 074-918-864-487-033; 075-069-230-055-960; 075-984-788-630-986; 078-297-346-675-188; 079-272-015-884-933; 079-311-695-178-678; 080-035-851-631-786; 081-096-405-494-879; 081-243-634-616-662; 083-934-418-989-822; 084-108-439-205-03X; 085-949-692-016-147; 086-303-116-415-688; 087-032-746-063-394; 087-371-592-748-249; 089-111-539-551-836; 092-191-541-626-156; 092-338-283-266-517; 093-392-842-911-10X; 093-470-574-197-085; 097-301-108-256-138; 101-769-047-357-221; 102-563-368-225-716; 104-495-326-573-684; 106-831-281-915-70X; 107-276-900-991-821; 108-699-697-462-852; 109-768-655-748-687; 110-789-762-580-590; 111-689-190-292-726; 111-965-437-370-676; 112-994-767-736-975; 113-730-195-355-09X; 113-854-175-269-738; 115-856-528-752-592; 116-170-030-445-093; 117-974-142-070-038; 120-076-914-410-615; 120-974-286-046-262; 122-259-225-868-713; 123-313-540-896-141; 125-409-753-350-328; 127-827-031-856-313; 128-217-524-056-953; 128-341-626-540-488; 128-806-154-332-185; 129-128-767-869-942; 129-458-218-583-396; 132-659-342-818-366; 137-380-338-835-220; 137-601-836-697-533; 137-641-302-865-148; 139-521-042-765-090; 140-327-803-982-601; 141-200-607-894-303; 141-487-851-921-423; 142-379-943-885-771; 149-156-500-619-50X; 149-520-218-719-169; 149-552-500-300-94X; 152-133-070-504-37X; 152-838-322-589-93X; 153-362-960-736-979; 155-115-201-838-602; 157-290-067-084-993; 157-960-395-074-241; 160-903-033-975-816; 161-795-587-232-185; 162-040-976-798-781; 166-880-761-664-679; 167-278-339-710-662; 170-336-013-910-948; 173-528-854-366-727; 175-236-436-609-771; 176-613-431-700-098; 177-154-257-386-019; 181-172-931-715-94X; 181-947-028-333-014; 184-718-690-969-228; 184-886-355-410-104; 185-740-917-143-680; 187-657-750-536-145; 188-109-281-521-600; 189-977-017-910-793; 191-511-902-047-352; 199-801-580-386-517,21,false,, -128-132-484-392-203,Supplementary Materials to bibliometric-based evaluation on the use of agri-food waste and byproducts as a self-sufficient fish feed materials for strengthening sustainable aquaculture,2023-01-01,2023,dataset,Figshare,,,,Adhita Sri Prabakusuma,"The intellectual structure of the research on the use of agri-food waste and byproducts as self-sufficient fish feed materials, based on 922 Scopus-indexed core collection documents from 252 journals written by 4,420 authors from 73 countries with an annual growth rate of 18.65% over the last four years (2019–2022), was analyzed in this comprehensive review. The review implemented a knowledge domain visualization approach using VOSviewer and Biblioshiny in the Bibliometrix R-package to investigate the basic scientometric profile of the selected fields, including the main relevant journals, influential authors, representative references, the number of potential collaborative networks among institutions and countries, emerging research trends, and the knowledge structure.",,,,,Food waste; Aquaculture; Fish ; Environmental science; Business; Waste management; Fishery; Engineering; Biology,,,,,https://figshare.com/articles/dataset/Supplementary_Materials_to_bibliometric-based_evaluation_on_the_use_of_agri-food_waste_and_byproducts_as_a_self-sufficient_fish_feed_materials_for_strengthening_sustainable_aquaculture/21879066,http://dx.doi.org/10.6084/m9.figshare.21879066,,10.6084/m9.figshare.21879066,,,0,,0,true,cc-by,gold -128-815-639-327-151,Academic Entrepreneurship Ecosystems: Systematic Literature Review and Future Research Directions,2024-02-16,2024,journal article,Journal of the Knowledge Economy,18687873; 18687865,Springer Science and Business Media LLC,Germany,Maria Patrocínia Correia; Carla Susana Marques; Rui Silva; Veland Ramadani,"Abstract; Research on the entrepreneurship ecosystem, based on different data and scales, limits the acceptance of a single definition. This conceptual limitation and the still recent research and higher education institutions have come to be seen as ecosystems associated with entrepreneurship. The aim of this study is to contribute to the field of knowledge, identify current and emerging thematic areas and trends and reveal the scientific roots of research on entrepreneurial ecosystems and their relationship with higher education institutions. A bibliometric analysis was developed to analyse a final sample of 110 articles published between 2011 and 2022. In order to develop the analysis, Bibliometrix R-Tool was used and the metadata of two databases (Web of Science and Scopus) was retrieved and merged. The software creates a reference co-citation’s map, which allowed emphasize the state of the art and indicate three thematic clusters: (i) the importance of the higher education context for the entrepreneurial ecosystem, (ii) the evolution and challenges of entrepreneurship education and (iii) academic entrepreneurship ecosystems. The paper concludes by suggesting future research focused on the importance of building an integrated approach to entrepreneurial ecosystems and higher education institutions on a context regional scale.",15,4,17498,17528,Entrepreneurship; Systematic review; Business; Political science; MEDLINE; Finance; Law,,,,FCT; Universidade de Trás-os-Montes e Alto Douro,https://link.springer.com/content/pdf/10.1007/s13132-024-01819-x.pdf https://doi.org/10.1007/s13132-024-01819-x,http://dx.doi.org/10.1007/s13132-024-01819-x,,10.1007/s13132-024-01819-x,,,0,004-500-240-722-886; 005-573-184-642-112; 009-034-068-837-37X; 011-447-247-214-44X; 013-507-404-965-47X; 014-195-943-700-223; 014-412-269-149-780; 015-970-789-133-056; 016-298-612-478-773; 017-208-427-868-758; 018-830-476-769-971; 018-922-858-288-864; 021-967-429-735-387; 023-771-664-214-942; 029-659-925-700-77X; 035-868-866-563-952; 039-532-191-557-090; 039-535-703-086-792; 043-846-676-381-00X; 044-138-797-984-113; 046-498-682-319-772; 047-490-304-377-166; 047-698-290-171-329; 048-607-107-052-576; 052-998-660-681-285; 054-225-715-151-125; 054-291-120-569-00X; 055-657-583-317-669; 055-798-736-070-708; 057-949-532-635-082; 059-170-820-194-406; 059-243-491-431-224; 059-309-977-616-682; 060-761-984-714-308; 060-781-274-872-262; 066-272-965-630-580; 067-657-975-259-248; 067-890-669-197-561; 069-605-714-825-342; 075-614-634-506-167; 077-351-759-424-617; 077-699-239-368-671; 080-286-153-918-41X; 080-390-488-148-293; 080-843-212-662-450; 080-871-770-582-875; 080-908-243-675-937; 085-001-502-383-40X; 087-043-499-337-311; 088-222-700-015-77X; 096-288-263-495-833; 098-628-420-450-964; 098-752-214-875-45X; 106-169-125-911-13X; 106-713-409-456-892; 106-967-719-331-374; 115-922-623-993-880; 116-813-932-257-67X; 119-562-542-325-302; 120-094-718-338-889; 122-307-450-479-611; 122-655-598-052-201; 122-827-252-276-011; 124-007-039-592-68X; 124-037-795-341-349; 128-245-219-188-19X; 129-260-463-481-461; 132-675-363-632-632; 134-792-428-462-124; 139-495-046-438-218; 161-825-995-650-858; 179-267-135-021-680; 183-588-004-651-975; 184-715-050-197-908,10,true,cc-by,hybrid -129-051-293-093-237,A Bibliometric Analysis of the Trends in the Research on Wearable Technologies for Cardiovascular Diseases.,2022-11-03,2022,journal article,Studies in health technology and informatics,18798365; 09269630,IOS Press,Netherlands,Ginette E A Kpadjouda Job; Jules Degila; S Arnaud R M Ahouandjinou; Vinasetan R Houndji; M Lamine Ba,"In this paper, a bibliometric analysis of research on wearable technologies for cardiovascular diseases was conducted with Bibliometrix and based on 1675 papers collected in Scopus from 2000 to 2022, and interesting results were presented. The US and China stood out for their sustained productivity in the field of cardiovascular diseases. The examination of the authors' keywords revealed that between 2000-01 and 2009-12, ""Respiration"" and ""personalized applications"" were the most popular research topics, however from 2010-01 to 2019-12, attention was given to ""ECG,"" ""Wearable devices,"" ""Wearable sensors,"" and ""heart rate"". This study suggests that in the present decade, researchers should focus on topics related to artificial intelligence, hypertension, ECG, wearable sensors, and African countries must address their technological gap in the coming years.",299,,256,,Wearable computer; Wearable technology; Bibliometrics; Computer science; Data science; Scopus; Field (mathematics); Productivity; China; Medicine; MEDLINE; Political science; World Wide Web; Economic growth; Mathematics; Pure mathematics; Law; Economics; Embedded system,Bibliometric; Bibliometrix; Cardiovascular; Wearable,Humans; Artificial Intelligence; Cardiovascular Diseases/diagnosis; Wearable Electronic Devices; Bibliometrics; Technology,,,https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI220994 https://doi.org/10.3233/shti220994,http://dx.doi.org/10.3233/shti220994,36325872,10.3233/shti220994,,,0,,2,true,cc-by-nc,hybrid -129-102-618-400-854,The role of STEM Education in improving the quality of education: a bibliometric study,2022-08-08,2022,journal article,International Journal of Technology and Design Education,09577572; 15731804,Springer Science and Business Media LLC,Netherlands,Seyedh Mahboobeh Jamali; Nader Ale Ebrahim; Fatemeh Jamali,"The United Nations (UN) has launched several initiatives to promote the role of education in Sustainable Development Goals (SDGs) and set Goal 4 for quality education among other SDGs. The integrated Science, Technology, Engineering, and Mathematics (STEM) approach is a promising educational framework for sustainable development that improves education quality. In this study, a bibliometric analysis was conducted to evaluate the scientific results of the role of integrated STEM education specifically in improving the quality of education (SDG 4). A hundred and fifty publications, with an increasing trend in the number of documents each year, out of the total number of 74,879 documents related to “education quality” and 5,430 documents related to “STEM education” were chosen from the SCOPUS database. The study analyzes the growth and development of research activities in the area of “STEM education” and “Quality education” as reflected in the publications output in the time span of 27 years from 1993 to 2020. The publication and citation trends, the most frequently used keywords, the most influential authors and journals, and the research hotspots were investigated using VoSviewer and Bibliometrix software. Accordingly, the United States happened to be the most productive country in this field owning two-thirds of the number of publications. The “Science Education” journal is ranked at the top of the highly cited journals. The findings show that topics such as “early childhood education”, “computing education”, and “environmental education” are the main hotspots in the research area of STEM and quality of education. The results of this study will help enhance the understanding of integrated STEM education in improving the quality of education and will support future works in this area.",33,3,819,840,Science education; Scopus; Quality (philosophy); Sustainable development; Higher education; Education for sustainable development; Political science; Mathematics education; Psychology; Philosophy; MEDLINE; Epistemology; Law,,,,,https://hal.science/hal-03752150/document https://hal.archives-ouvertes.fr/hal-03752150 https://zenodo.org/records/6997868/files/STEM%20Education%20and%20Quality%20of%20Education.pdf https://zenodo.org/record/6997868 https://www.ssoar.info/ssoar/bitstream/document/80956/1/ssoar-ijtde-2022-3-jamali_et_al-The_Role_of_STEM_Education.pdf https://www.ssoar.info/ssoar/handle/document/80956 https://hal.archives-ouvertes.fr/hal-03752150/file/STEM%20Education%20and%20Quality%20of%20Education.pdf https://hal.science/hal-03752150/file/STEM%20Education%20and%20Quality%20of%20Education.pdf https://hal.archives-ouvertes.fr/hal-03752150/document https://mpra.ub.uni-muenchen.de/114214/1/MPRA_paper_114214.pdf,http://dx.doi.org/10.1007/s10798-022-09762-1,,10.1007/s10798-022-09762-1,,,0,001-413-505-334-244; 002-052-422-936-00X; 002-104-356-194-395; 002-945-451-053-626; 003-687-891-819-717; 004-454-707-633-090; 006-448-443-974-423; 006-889-256-793-84X; 007-150-511-953-187; 007-217-731-151-040; 007-560-555-625-558; 007-828-444-956-332; 009-082-702-900-118; 011-583-149-625-495; 012-114-389-955-80X; 012-796-408-235-447; 013-507-404-965-47X; 013-737-704-009-598; 014-536-280-443-985; 019-471-650-523-307; 026-580-976-493-722; 026-598-072-205-922; 027-542-972-462-864; 027-690-220-065-414; 030-354-165-157-660; 032-318-770-533-876; 032-978-932-739-548; 034-418-127-209-189; 034-477-056-970-295; 035-785-858-400-527; 039-087-547-476-388; 040-177-850-026-245; 045-539-734-954-658; 046-382-705-352-053; 051-106-179-711-983; 053-638-162-842-100; 055-749-872-948-852; 057-475-961-325-54X; 065-010-405-236-060; 066-213-200-362-852; 066-225-891-742-413; 069-392-222-165-441; 075-455-308-030-17X; 078-644-843-746-243; 082-305-676-073-19X; 082-467-177-981-419; 087-881-074-998-950; 089-929-793-025-410; 093-665-874-973-63X; 094-828-604-086-723; 099-276-077-336-282; 102-997-173-530-743; 103-355-170-695-35X; 104-098-248-760-185; 105-453-522-160-351; 115-347-719-589-649; 119-847-285-184-623; 120-873-210-560-844; 123-227-503-852-587; 124-210-811-645-745; 124-849-260-268-038; 125-531-613-225-655; 126-412-225-083-805; 128-746-717-699-369; 129-359-555-135-080; 148-074-408-211-979; 151-814-658-393-479; 152-719-036-725-687; 153-282-924-188-573; 154-675-162-329-547; 163-204-974-564-580; 174-416-286-160-631; 175-615-684-211-498; 175-921-512-595-742; 187-058-106-749-647,49,true,,green -129-131-841-111-265,Research contribution of bibliometric studies related to sustainable development goals and sustainability,2024-01-15,2024,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Raghu Raman; Hiran Lathabhai; Debidutta Pattnaik; Chandan Kumar; Prema Nedungadi,"AbstractThis bibliometric study analyzes 1433 former reviews on Sustainable Development Goals (SDGs) and Sustainability, providing a comprehensive overview of the evolving research landscape in this domain. Notably, we observe a substantial annual growth rate of 74% in publications and a remarkable 171% increase in total citations from 2016 to 2022, reflecting a growing interest in this area. We identify the leading countries and institutions contributing to quantitative reviews on SDGs and Sustainability. SDG 12 (Sustainable Consumption and Production) emerges as the most extensively studied and is highly represented in influential journals like Sustainability and the Journal of Cleaner Production. Across various research fields, SDGs 12 and 11 (Sustainable Cities and Communities) stand out, with SDGs 4 (Quality Education), 5 (Gender Equality), and 15 (Life on Land) showing significance in specific domains. Thematic analysis reveals key topics like environmental protection, circular economy, life cycle assessment, and supply chain management, with strong connections to SDG 12. Further clusters highlight environmental management, renewable energy, and energy policy linked to SDG 7 (Affordable and Clean Energy), along with a smaller cluster focusing on urbanization driven by SDG 11. Network analysis emphasizes the critical roles of SDGs 12 and 9 (Industry Innovation and Infrastructure) in achieving a sustainable future. However, alternative social network indicators highlight the potential influence of SDGs 8 (Decent Work and Economic Growth), 16 (Peace, Justice and Strong Institutions), and 17 (Partnerships for the Goals) on other goals. Intriguingly, mainstream SDG research predominantly focuses on SDGs 3 and 7, presenting challenges due to the volume and complexity of related publications. While SDG 7 could find suitable outlets in leading journals, addressing SDG 3’s (Good Health and Well Being) complexity remains a formidable task. Nevertheless, conducting bibliometric studies on SDGs 3, 7, and 13 (Climate Action) offers promising opportunities in future if the associated challenges are addressed effectively.",5,1,,,Sustainability; Sustainable development; Environmental economics; Mainstream; Resource efficiency; Environmental resource management; Environmental planning; Business; Political science; Regional science; Economics; Geography; Ecology; Law; Biology,,,,,https://link.springer.com/content/pdf/10.1007/s43621-024-00182-w.pdf https://doi.org/10.1007/s43621-024-00182-w,http://dx.doi.org/10.1007/s43621-024-00182-w,,10.1007/s43621-024-00182-w,,,0,000-436-610-244-932; 001-393-001-635-312; 002-052-422-936-00X; 002-409-058-987-108; 003-845-089-560-905; 004-080-005-673-967; 005-956-565-206-267; 006-884-943-529-423; 012-153-947-477-534; 013-403-735-081-525; 013-507-404-965-47X; 013-972-311-791-646; 014-727-582-122-88X; 015-169-522-476-160; 015-249-067-927-117; 015-420-876-125-947; 015-756-568-009-177; 017-966-996-814-613; 018-213-226-156-669; 020-265-055-413-005; 021-187-695-321-390; 021-291-004-183-292; 021-451-895-964-796; 021-775-005-542-657; 023-927-221-065-800; 024-119-309-428-689; 025-411-497-476-809; 026-179-209-405-866; 026-899-816-574-755; 026-962-817-340-271; 029-420-167-353-195; 029-698-509-669-39X; 030-383-591-112-994; 032-738-912-841-593; 035-052-709-996-20X; 039-900-046-535-027; 040-473-278-619-758; 040-637-811-266-793; 042-228-490-689-212; 042-478-668-086-876; 045-465-367-752-050; 048-446-472-989-768; 049-391-379-302-694; 053-598-695-896-482; 054-818-565-070-154; 055-307-103-788-841; 060-110-039-971-60X; 061-347-934-524-015; 061-957-289-547-350; 063-197-084-302-089; 066-539-836-864-719; 066-817-022-275-453; 070-991-282-066-330; 072-491-960-118-569; 072-833-024-533-417; 075-004-097-669-017; 077-382-405-543-59X; 078-544-894-847-222; 080-724-759-730-013; 081-261-752-577-851; 089-825-425-366-565; 096-472-527-387-204; 096-853-306-718-283; 101-752-490-869-458; 103-515-124-208-805; 106-217-419-751-120; 111-792-162-428-118; 112-404-384-444-85X; 113-682-442-621-962; 120-975-417-040-341; 127-580-512-767-74X; 131-950-602-376-531; 141-368-416-545-476; 143-229-770-694-047; 143-936-693-364-687; 152-284-349-768-485; 153-282-924-188-573; 153-548-072-198-346; 160-496-711-000-132; 169-178-587-740-478; 169-981-897-619-174; 191-071-691-061-325; 193-377-079-485-53X; 196-541-648-095-488; 198-937-578-126-763,36,true,cc-by,gold -129-152-662-480-332,Mapping trends and knowledge structure of energy efficiency research: what we know and where we are going,2021-05-18,2021,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Masnun Mahi; Izlin Ismail; Seuk Wai Phoong; Che Ruhana Isa,,28,27,35327,35345,Energy policy; Climate change; Environmental economics; Socioeconomic status; Political science; Efficient energy use; Citation index; Greenhouse gas; Sustainability; Kyoto Protocol,Bibliometric analysis; Carbon emissions; Climate change; Energy Policy; Energy efficiency; Energy sustainability,Bibliometrics; Climate Change; Commerce; Conservation of Energy Resources; Publications,,"Ministry of Higher Education, Malaysia (LR001B-2016A); University of Malaya, Malaysia (LR001B-2016A)",https://www.ncbi.nlm.nih.gov/pubmed/34002315 http://www.ncbi.nlm.nih.gov/pubmed/34002315 https://europepmc.org/article/MED/34002315 https://link.springer.com/article/10.1007/s11356-021-14367-7 https://pubmed.ncbi.nlm.nih.gov/34002315/,http://dx.doi.org/10.1007/s11356-021-14367-7,34002315,10.1007/s11356-021-14367-7,3162445546,,0,005-236-570-689-261; 005-893-127-733-440; 007-016-826-558-870; 007-163-504-943-653; 009-286-240-384-618; 009-820-644-002-863; 013-507-404-965-47X; 015-451-056-948-43X; 017-750-600-412-958; 018-016-514-072-15X; 018-897-457-613-943; 020-810-652-634-00X; 023-243-627-170-734; 023-256-378-450-438; 023-527-718-075-323; 027-334-714-884-929; 027-406-540-345-844; 027-768-062-807-693; 029-624-788-210-642; 031-126-823-255-791; 033-741-878-859-565; 034-577-058-373-580; 034-768-039-318-254; 035-710-711-709-208; 040-602-802-209-455; 042-167-740-200-381; 042-327-759-469-428; 043-338-137-190-684; 044-484-644-347-983; 045-368-114-501-494; 047-134-478-431-993; 050-893-374-534-416; 051-622-079-632-576; 051-865-643-777-765; 052-016-769-698-747; 053-659-763-234-007; 068-518-056-795-628; 070-991-282-066-330; 073-383-238-435-039; 074-708-305-856-570; 079-540-855-767-404; 082-790-699-340-571; 082-956-365-984-948; 085-511-939-346-548; 085-630-287-822-773; 089-640-481-882-803; 093-678-829-415-105; 096-457-234-171-674; 102-129-149-906-819; 102-129-872-362-478; 102-267-839-174-315; 107-265-025-742-267; 115-433-185-325-016; 116-225-422-115-160; 119-589-000-749-629; 122-415-544-444-960; 124-707-866-411-974; 132-946-951-460-277; 134-461-231-093-98X; 137-309-554-094-058; 141-070-294-700-586; 148-060-875-242-793; 151-109-152-647-845; 162-984-881-646-230; 169-700-177-074-491; 169-989-391-877-607; 170-928-358-880-296; 172-767-918-918-650; 176-523-638-330-697; 180-178-506-396-993; 183-754-704-548-419; 186-273-741-847-305,43,false,, -129-519-475-307-68X,Evolution of artificial intelligence in healthcare: a 30-year bibliometric study.,2025-01-15,2025,journal article,Frontiers in medicine,2296858x,Frontiers Media SA,Switzerland,Yaojue Xie; Yuansheng Zhai; Guihua Lu,"In recent years, the development of artificial intelligence (AI) technologies, including machine learning, deep learning, and large language models, has significantly supported clinical work. Concurrently, the integration of artificial intelligence with the medical field has garnered increasing attention from medical experts. This study undertakes a dynamic and longitudinal bibliometric analysis of AI publications within the healthcare sector over the past three decades to investigate the current status and trends of the fusion between medicine and artificial intelligence.; Following a search on the Web of Science, researchers retrieved all reviews and original articles concerning artificial intelligence in healthcare published between January 1993 and December 2023. The analysis employed Bibliometrix, Biblioshiny, and Microsoft Excel, incorporating the bibliometrix R package for data mining and analysis, and visualized the observed trends in bibliometrics.; A total of 22,950 documents were collected in this study. From 1993 to 2023, there was a discernible upward trajectory in scientific output within bibliometrics. The United States and China emerged as primary contributors to medical artificial intelligence research, with Harvard University leading in publication volume among institutions. Notably, the rapid expansion of emerging topics such as COVID-19 and new drug discovery in recent years is noteworthy. Furthermore, the top five most cited papers in 2023 were all pertinent to the theme of ChatGPT.; This study reveals a sustained explosive growth trend in AI technologies within the healthcare sector in recent years, with increasingly profound applications in medicine. Additionally, medical artificial intelligence research is dynamically evolving with the advent of new technologies. Moving forward, concerted efforts to bolster international collaboration and enhance comprehension and utilization of AI technologies are imperative for fostering novel innovations in healthcare.; Copyright © 2025 Xie, Zhai and Lu.",11,,1505692,,Health care; Artificial intelligence; Computer science; Psychology; Political science; Law,ChatGPT; artificial intelligence; bibliometric study; health care; medicine,,,,,http://dx.doi.org/10.3389/fmed.2024.1505692,39882522,10.3389/fmed.2024.1505692,,PMC11775008,0,000-452-908-115-500; 003-921-849-886-855; 004-903-459-604-880; 005-577-524-198-846; 007-655-642-284-140; 009-091-228-784-58X; 015-441-763-900-751; 016-179-985-570-36X; 020-359-159-960-860; 022-276-544-161-933; 023-414-992-431-174; 023-478-802-370-116; 024-984-879-737-164; 033-904-395-637-646; 038-496-616-340-443; 040-631-471-767-542; 046-474-009-349-270; 051-455-791-863-778; 059-252-360-342-867; 061-566-591-617-059; 062-049-479-440-397; 063-104-480-070-392; 076-040-733-092-082; 076-716-779-391-237; 077-044-033-853-201; 079-041-796-305-851; 080-118-387-618-96X; 090-191-307-040-947; 090-739-145-400-727; 096-615-272-257-138; 102-500-520-550-866; 103-617-200-792-204; 106-700-672-794-431; 110-414-173-667-523; 112-930-253-962-614; 113-156-377-833-626; 116-667-617-206-415; 126-036-690-442-539; 132-281-387-323-138; 165-762-042-333-335; 167-252-793-890-442; 170-161-736-748-786; 171-554-978-740-211; 174-551-669-832-310; 186-249-073-938-323; 186-585-258-382-328; 189-100-706-719-07X; 191-865-502-709-95X; 198-980-143-320-958,5,true,cc-by,gold -129-547-443-710-755,A Bibliometric Analysis of Green Skills Research in Vocational Education: 2018-2022,2024-11-08,2024,journal article,"Elinvo (Electronics, Informatics, and Vocational Education)",24772399; 25806424,Universitas Negeri Yogyakarta,,Muhammad Noor Fitriyanto; Wagiran Wagiran; Fathul Zannah; Dian Novian; Hamsi Mansur,"Green skills (GSs) have become one of the important strategies for achieving sustainable development. It can make the environment effective for social and economic development. The aim of this research is to reveal data on the evolution and development of green skills and trends in the development of green jobs throughout the world. This research uses R Studio and Bibliometrix to analyze 198 papers related to green skills in green jobs published from 2018 to 2022 in the Scopus database using Bibliometrix and visualization mapping methods. The results show a substantial increase in the number of studies GSs in recent years, with the focus area in European and American countries leading this research. Aspects of Will, manufacturing and Energy, and Journals of Green Environmental Management are the first three journals cited in the study of GSs.  Studying the cited literature together on environmentally friendly skills includes, among other things, the relationship between other skills and ecosystems with human good health, green construction, evaluation and green management of environmentally friendly competencies, and analysis of specific aspects of environmentally friendly skills. The results of the analysis of green skills grouping keywords show that there is research that concentrates on green skills in the fields of education, ecosystem services, climate change, and biodiversity protection. In conclusion, this research provides a reference for future studies of green skills necessary for the development of a sustainable educational environment, such as a multidisciplinary approach, adaptation of new technologies, partnerships with sustainable technology green industries, and environmental awareness.",9,1,178,186,Vocational education; Mathematics education; Psychology; Engineering; Pedagogy,,,,,http://journal.uny.ac.id/index.php/elinvo/article/download/71890/22501 https://doi.org/10.21831/elinvo.v9i1.71890,http://dx.doi.org/10.21831/elinvo.v9i1.71890,,10.21831/elinvo.v9i1.71890,,,0,,0,true,cc-by-nc,hybrid -129-744-897-590-148,Bibliometric Analysis on Islamic Spiritual Care with Special Reference to Prophetic Medicine or al-Ṭibb al-Nabawī,2024-06-28,2024,journal article,Intellectual Discourse,22895639; 01284878,IIUM Press,Malaysia,Zunaidah Mohd. Marzuki; Nurulhaniy Ahmad Fuad; Jamilah Hanum Abdul Khaiyom; Normala Mohd Adnan; Aida Mokhtar,"This study focuses on a bibliometric analysis that explores trends on Prophetic medicine (al-ṭibb al-nabawī) within Islamic spiritual care. Due to the scarcity of literature, it utilised “Islamic Spiritual Care” as a search term on Dimensions.ai, rather than “Prophetic Medicine” or “Ḥadīth.” Initially, 325 titles were identified, with 56 of them meeting the criteria for analysis. The data was then analysed using the Biblioshiny interface of the Bibliometrix R package. The results reveal a steady rise in Islamic spiritual care studies over the past decade, despite notable fluctuations. The exploration of Prophetic medicine within the framework of spiritual care lacks sufficient emphasis, as indicated by the analysis of the 56 pertinent sources, particularly from the most frequent words and co-occurrence network map of authors’ keywords. This research, to the knowledge of the authors, is a pioneering bibliometric analysis in the field.; Keywords: Bibliometric, Islamic spiritual care, ḥadīth, Dimensions.ai, Bibliometrix R package;  ",32,1,,,Islam; Spiritual care; Scarcity; Bibliometrics; Field (mathematics); Sociology; Social science; Alternative medicine; Traditional medicine; Psychology; Spirituality; Medicine; Library science; Philosophy; Computer science; Theology; Pathology; Mathematics; Pure mathematics; Economics; Microeconomics,,,,,,http://dx.doi.org/10.31436/id.v32i1.2147,,10.31436/id.v32i1.2147,,,0,,0,false,, -129-934-754-291-105,Bibliometric analysis of laser powder bed additive manufacturing of high-entropy alloys: where are we and how far have we come?,2024-10-27,2024,journal article,Progress in Additive Manufacturing,23639512; 23639520,Springer Science and Business Media LLC,,Caner Bulut; Fatih Yıldız,,10,5,3267,3286,Materials science; Metallurgy; Environmental science; Process engineering; Earth science; Geology; Engineering,,,,,,http://dx.doi.org/10.1007/s40964-024-00840-5,,10.1007/s40964-024-00840-5,,,0,001-628-752-090-580; 003-310-656-958-813; 003-895-016-795-602; 007-623-464-984-710; 008-247-051-830-385; 008-272-309-857-505; 008-791-922-209-367; 009-110-990-881-059; 011-227-300-363-862; 012-178-312-975-370; 014-147-288-773-234; 016-697-907-678-527; 018-161-148-777-053; 021-133-973-860-041; 024-590-664-902-976; 027-318-761-017-721; 027-885-134-592-939; 028-569-784-800-543; 031-274-718-244-024; 032-319-228-787-82X; 033-154-171-854-318; 034-056-163-844-408; 034-162-655-070-428; 034-734-330-038-869; 038-181-849-084-632; 039-823-133-617-366; 041-903-927-630-599; 042-857-940-593-130; 043-282-562-983-28X; 043-719-302-545-370; 044-772-929-611-844; 047-898-835-201-521; 048-799-164-254-245; 050-235-599-165-442; 050-340-801-148-596; 050-454-528-919-278; 052-991-622-673-450; 053-990-625-252-725; 056-943-006-385-593; 057-786-661-199-877; 060-368-322-920-099; 060-904-771-223-914; 062-835-370-652-298; 068-006-464-123-426; 072-170-730-831-759; 075-321-324-982-687; 077-385-145-035-209; 079-557-924-964-198; 083-284-177-142-759; 085-166-401-873-982; 085-446-966-301-013; 085-507-324-265-15X; 086-014-314-846-824; 086-359-654-910-347; 088-054-201-044-269; 090-158-964-260-558; 090-541-775-364-341; 093-265-495-374-802; 093-780-788-721-640; 094-354-064-677-212; 094-500-491-898-901; 096-163-187-230-972; 096-344-859-371-94X; 096-406-287-747-382; 098-083-886-309-818; 101-784-768-958-84X; 104-107-945-811-517; 105-106-030-917-948; 105-863-286-941-018; 106-740-475-954-121; 111-097-022-121-929; 117-149-238-525-199; 117-959-623-535-97X; 118-777-567-565-777; 121-289-658-230-871; 121-888-705-265-060; 125-722-134-941-04X; 125-750-064-076-545; 130-266-665-227-800; 130-759-600-263-822; 131-070-774-964-422; 131-758-823-661-811; 134-266-747-760-508; 134-660-385-684-290; 145-018-502-523-877; 147-270-810-731-624; 147-441-142-969-656; 160-848-875-646-876; 163-286-081-391-872; 166-557-603-720-460; 167-904-681-208-69X; 168-300-867-019-079; 170-015-576-936-503; 170-775-810-619-71X; 179-231-897-710-680; 188-370-159-366-407; 192-887-124-927-821; 195-874-729-576-506; 197-115-623-575-383; 197-569-973-293-462,0,false,, -131-656-957-020-844,Analysis Of Articles on Evidence-Based Medicine,2021-11-25,2021,journal article,Gevher Nesibe Journal IESDR,27177394,Iktisadi Kalkinma ve Sosyal Arastirmalar Dernegi,,Umut BEYLİK,"The aim of this study is to conduct a bibliometric analysis of articles on evidence-based medicine. Using Bibliometrix and VOSviwer software, the most efficient author, country, organization, and journals were identified. Web of Science articles between the years of 1975-2019 were downloaded with a search strategy and analyzed with Bibliometrix and VOSviwer software. It has been observed that evidence-based medicine articles were grouped under three main clusters (Management and Decision Support, Drug and Experiment and Measurment). The first three countries that have the highest international collaboration rate are Switzerland, New Zealand, and Sweden. The first five countries regarding publication numbers are the USA, United Kingdom, Canada, Australia, and Germany. While Khan and Green have the highest grade in h and g index; Baglı, Castagnetti and Fossum have the highest grade in m index. Guyatt is the author who has the highest number of citations whereas Phillips is the one who has the most publications. While, on one hand, evidence-based medicine extends its function in illness and drug treatments, on the other hand, it is used as policy input to improve the education, curriculum, and the health system. Policy-makers, decision-makers, educators, and researchers can develop strategies according to the findings identified above.",6,15,87,108,Index (typography); Web of science; Alternative medicine; Curriculum; Evidence-based medicine; Medicine; Medical education; Library science; MEDLINE; Family medicine; Political science; Computer science; Law; World Wide Web; Pathology,,,,,,http://dx.doi.org/10.46648/gnj.288,,10.46648/gnj.288,,,0,,2,false,, -131-832-823-366-831,Sexual Affectivity in Autism Spectrum Disorder: Bibliometric Profile of Scientific Production.,2024-09-13,2024,journal article,Archives of sexual behavior,15732800; 00040002,Springer Science and Business Media LLC,United States,Jordi Torralbas-Ortega; Victòria Valls-Ibáñez; Judith Roca; Carme Campoy-Guerrero; Meritxell Sastre-Rus; Judith García-Expósito,"The aim of the present study was to describe the scientific production on sexuality and affectivity of autistic people. The inclusion criteria were articles published in all languages from the year 2000 to 2023, excluding reviews, proceedings, and other works not considered original. The search was performed in the Web of Science Core Collection and RStudio was utilized to analyze the records, with the ""Bibliometrix 4.1.0"" package and the VOSviewer software. A total of 314 articles were included, from the USA, Australia, and parts of Europe. The production peak was found in the year 2020, the most cited articles referred to the children's population, and the most important journals were specialized on the subject. As for the thematic content, 29 keywords emerged that were grouped into three clusters. In the first group, children associated with vulnerability and victimization were underlined, in which multifocal interventions were needed to prevent risk; in the second, we found adolescents and the need for sex education that is adapted and comprehensive; and lastly, adults who must be able to perform an adequate transition that eases the adaptation of neurodivergent individuals.",54,2,673,684,Psychology; Vulnerability (computing); Inclusion (mineral); Population; Autism; Psychological intervention; Autism spectrum disorder; Human sexuality; Developmental psychology; Clinical psychology; Social psychology; Medicine; Psychiatry; Environmental health; Sociology; Computer science; Gender studies; Computer security,Affective symptoms; Autism spectrum disorder; Bibliometrics; Sexual behavior; Sexuality,Humans; Bibliometrics; Autism Spectrum Disorder/psychology; Child; Sexual Behavior/psychology; Adolescent; Male; Female; Sexuality/psychology; Adult,,Universitat de Lleida; Óbuda University,,http://dx.doi.org/10.1007/s10508-024-02996-1,39269514,10.1007/s10508-024-02996-1,,PMC11836160,0,001-249-592-567-756; 005-237-212-285-632; 005-930-049-486-56X; 006-880-773-806-45X; 009-563-030-807-873; 013-507-404-965-47X; 015-023-986-395-156; 017-750-600-412-958; 018-911-344-760-355; 018-922-884-792-212; 019-830-002-232-378; 020-420-054-730-284; 021-197-361-595-710; 021-760-464-240-285; 021-996-778-147-180; 028-251-813-488-940; 029-553-976-754-019; 032-122-789-091-452; 033-859-410-757-110; 038-317-832-918-186; 041-054-894-922-398; 041-885-145-027-49X; 043-582-637-949-778; 050-557-597-713-742; 051-430-777-231-888; 056-402-333-287-462; 056-614-470-888-285; 059-642-270-769-342; 059-790-921-377-778; 060-295-630-392-254; 061-302-663-625-80X; 062-832-942-177-725; 069-243-611-792-888; 070-755-255-789-889; 073-775-823-470-313; 074-550-526-789-44X; 075-352-221-898-409; 077-672-780-264-299; 078-266-904-646-030; 078-784-253-302-540; 089-198-947-441-614; 096-841-002-113-762; 103-149-088-100-866; 113-532-601-359-735; 122-930-056-988-121; 130-149-452-562-346; 131-300-207-279-104; 132-846-699-398-10X; 135-106-498-613-745; 143-125-197-344-418; 148-671-973-659-421; 149-483-974-125-833; 156-743-394-145-805; 159-816-863-673-576; 170-081-707-885-490,0,true,cc-by,hybrid -132-017-479-603-580,Neuromarketing y las preferencias del consumidor desde web of science: Análisis bibliométrico,2025-04-03,2025,journal article,"Impulso, Revista de Administración",29599040,Universidad Privada Domingo Savio,,Guillermo Romaní Pillpe; Keila Soledad Macedo Inca; Massiel Wendy Anyosa Oré; Genaro Rodrigo Quintero; Verónica Fabiola Soto Guillinta,"Neuromarketing has gained relevance as a tool for understanding consumer behavior and preferences. This article examines the scientific production related to neuromarketing and consumer preferences through a bibliometric analysis of 554 records retrieved from the Web of Science database. Using R-Studio and bibliometrix v.4.1.4, most cited papers, frequent keywords and scientific impact metrics were examined. In addition, co-citation networks and thematic groupings were explored. The results highlight factors such as absolute and relative impact of neuromarketing studies, evidencing a bibliometric approach that connects science, innovation and strategic management. Keywords evolve around terms such as “cognition”, ‘emotion’ and “decision making”, reflecting a growth in the interdisciplinarity of the field. Cocitation networks reveal crucial nodes and patterns, providing a comprehensive view of research trends and priorities in neuromarketing.",5,10,103,117,Neuromarketing; Humanities; Political science; Philosophy; Business; Advertising,,,,,,http://dx.doi.org/10.59659/impulso.v.5i10.104,,10.59659/impulso.v.5i10.104,,,0,,0,true,cc-by-nc-sa,gold -132-648-621-660-879,Tendencias de investigación en la economía agrícola,2025-01-01,2025,journal article,Equidad y Desarrollo,23898844; 16927311,Universidad de La Salle,,Freddy Eliseo Hernández Jorge; Juliana Salazar Castaño,"The agricultural economy, fundamental to global development, is influenced by political and economic factors, exports and the international context. In recent years, the sustainability, demand and prices of agricultural products, as well as the crucial role of rural extension, have gained relevance. Using tools such as R-studio, bibliometrix and Tree of Science, and querying Scopus with terms such as “agricultural economics”, this field has been broken down into its classical roots, its current structure and its future trends. This analysis reveals an evolution towards a greater integration of sustainable practices, an adaptation to market fluctuations and a strengthening of rural extension as a key tool to face the agricultural challenges of the future.",,45,e1714,e1714,Cola (plant); Political science; Humanities; Philosophy; Biology; Botany,,,,,,http://dx.doi.org/10.19052/eq.vol1.iss45.5307,,10.19052/eq.vol1.iss45.5307,,,0,,0,true,,bronze -132-862-314-389-860,Navigating the storm: the SME way of tackling the pandemic crisis,2023-08-19,2023,journal article,Small Business Economics,0921898x; 15730913,Springer Science and Business Media LLC,Netherlands,Gagan Deep Sharma; Sascha Kraus; Amogh Talan; Mrinalini Srivastava; Christina Theodoraki,"Small and medium-sized enterprises (SMEs) are a major contributor to economic growth and a potential source of growth and employment globally. This article employs a bibliometric analysis approach to examine 135 research articles focused on the barriers encountered by SMEs and their strategic responses during the COVID-19 pandemic. Through this analysis, we present a conceptual diagram that highlights prominent challenges, including organizational barriers (e.g., financial crisis, liquidity constraints, and reduced purchasing power), operational barriers (e.g., scarcity of skilled workforce and limited access to raw materials), technological barriers (e.g., digitalization and forecasting capabilities), and strategic restrictions (e.g., resource limitations and disruptions in supply chains). We further explore approaches to overcoming these barriers, such as entrepreneurial resilience and innovation. The findings of this review underscore the importance of government policies aimed at supporting SMEs and facilitating their survival in the aftermath of crises. Moreover, given the impact of COVID-19, policies should also prioritize the involvement of SMEs and business owners in decision-making processes related to policy responses and recovery strategies.",63,1,221,241,Business; Entrepreneurship; Workforce; Small and medium-sized enterprises; Scarcity; Industrial organization; Small business; Marketing; Economics; Economic growth; Finance; Market economy,,,,,https://hal.science/hal-04676728/document https://hal.science/hal-04676728,http://dx.doi.org/10.1007/s11187-023-00810-1,,10.1007/s11187-023-00810-1,,,0,000-837-996-564-732; 002-251-501-310-744; 006-646-419-435-240; 013-056-555-182-069; 013-408-221-103-515; 013-524-854-219-241; 013-974-622-678-682; 018-351-817-580-336; 020-400-409-522-823; 020-810-352-622-55X; 022-225-527-754-876; 023-786-075-290-068; 025-302-119-966-613; 025-327-133-333-565; 025-724-153-635-471; 027-196-013-634-684; 028-024-626-308-019; 028-094-909-868-829; 029-087-799-772-164; 031-624-167-990-924; 032-617-115-209-420; 032-802-243-523-785; 035-582-970-808-469; 037-596-152-516-384; 039-780-762-389-418; 040-580-129-667-047; 042-755-259-129-09X; 046-837-763-656-74X; 046-992-864-415-70X; 047-464-360-781-236; 047-515-658-083-147; 050-382-810-849-445; 050-396-927-643-640; 051-369-156-333-363; 051-647-739-244-271; 054-818-565-070-154; 055-372-469-607-532; 060-007-507-983-64X; 060-132-227-258-868; 061-089-418-130-977; 062-400-243-783-938; 066-959-131-524-221; 068-812-980-987-788; 068-824-767-000-76X; 073-455-229-343-060; 074-824-493-869-851; 076-416-008-465-774; 076-651-773-930-450; 076-991-644-117-130; 077-286-743-641-846; 083-739-526-432-809; 085-555-021-369-759; 087-037-387-211-422; 087-189-549-581-200; 087-201-396-084-615; 087-633-366-398-137; 088-631-031-147-851; 090-731-522-534-055; 091-005-280-630-799; 095-728-074-467-649; 096-264-137-204-824; 097-140-163-750-708; 097-175-673-594-928; 098-298-948-599-813; 099-202-267-431-297; 099-346-054-110-927; 100-603-573-401-580; 102-138-013-656-536; 103-640-610-134-71X; 105-794-859-399-363; 106-445-173-246-507; 107-852-424-555-350; 107-908-513-309-258; 113-847-347-763-754; 114-337-833-829-946; 120-005-852-311-444; 120-885-678-404-810; 122-027-294-404-645; 123-202-581-406-928; 132-493-381-852-658; 138-996-910-342-374; 141-743-456-020-385; 143-758-800-295-869; 146-801-394-919-794; 147-238-016-843-792; 156-813-885-226-539; 158-339-957-256-76X; 162-033-314-828-528; 172-959-949-589-454; 179-529-657-462-333; 184-871-004-745-322; 191-488-300-017-639; 193-657-761-478-822,26,true,,bronze -132-913-397-211-810,A study on social media and higher education during the COVID-19 pandemic.,2023-03-20,2023,journal article,Universal access in the information society,16155297; 16155289,Springer Science and Business Media LLC,Germany,Sarthak Sengupta; Anurika Vaish,"Nowadays social media usage has increased drastically among the stakeholders of higher educational institutions. The COVID-19 pandemic has suddenly increased the surge of social media users due to the forced implementation of online pedagogy and travel restrictions. The research study presented in this paper attempted to analyze social media usage in higher education. The data were collected from primary and secondary sources with the help of leading research databases, survey questionnaires, the Delphi method, and brainstorming sessions. Statistical tools and analytic techniques incorporated in the study included bibliometric analysis, word cloud, co-occurrence network, thematic map, thematic evolution, co-word analysis, country-wise analysis along with collaboration network, statistical survey, mind mapping, and analytic hierarchy process. The study justified the aspects of social media usage in the higher educational environment. It was found that the research fraternity around the globe focused more on understanding the aspects of social media and higher education during the trying times of the Coronavirus crisis. The maximum impact of social media usage on higher education was found to be from teaching-learning and discussions, and public relations and networking. It was also found that social networking platforms like WhatsApp, YouTube, Facebook (Meta), LinkedIn, Instagram, and Twitter were very common among the stakeholders of higher education. This study is of huge importance because it can help in paving the way to strategize remedial measures for increasing positivity and minimizing the negativity of social media usage in institutions of higher education across the world.; The online version contains supplementary material available at 10.1007/s10209-023-00988-x.; © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.",23,3,1,1271,Coronavirus disease 2019 (COVID-19); Pandemic; Social media; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Computer science; World Wide Web; Medicine; Internal medicine; Outbreak; Disease; Infectious disease (medical specialty),Analytic hierarchy process; Bibliometric analysis; COVID-19 pandemic; Higher education; Social media,,,,https://link.springer.com/content/pdf/10.1007/s10209-023-00988-x.pdf https://doi.org/10.1007/s10209-023-00988-x,http://dx.doi.org/10.1007/s10209-023-00988-x,37361680,10.1007/s10209-023-00988-x,,PMC10025795,0,002-118-629-868-680; 002-272-341-694-402; 002-686-899-165-681; 005-639-233-013-603; 006-199-261-499-735; 007-388-534-440-157; 008-367-923-675-148; 009-459-188-075-326; 011-840-825-006-038; 011-854-399-312-637; 013-507-404-965-47X; 013-524-854-219-241; 014-491-521-266-275; 016-030-287-563-167; 016-629-320-073-268; 018-718-861-216-935; 022-023-667-231-30X; 024-956-708-930-121; 027-136-525-043-736; 027-692-924-446-302; 028-423-968-165-394; 029-085-329-487-909; 030-240-639-525-686; 033-883-554-372-412; 034-320-269-076-320; 036-960-728-423-298; 042-149-001-747-544; 042-797-857-313-378; 045-329-292-242-470; 046-135-310-325-407; 048-032-452-334-908; 049-098-511-920-332; 051-074-145-705-469; 051-219-736-534-758; 051-649-979-397-890; 052-492-369-608-738; 054-266-259-277-242; 061-506-456-862-671; 062-406-868-403-55X; 065-365-319-411-101; 067-945-415-622-236; 068-348-614-928-167; 068-835-585-441-170; 071-106-825-448-055; 071-471-931-531-122; 071-807-507-458-68X; 072-400-456-783-168; 073-443-706-092-818; 073-661-962-448-516; 074-624-086-360-170; 075-533-093-091-514; 077-223-705-582-963; 084-841-376-505-052; 089-601-373-548-443; 090-443-005-046-794; 091-882-282-586-861; 093-936-276-034-490; 095-595-442-928-394; 102-783-607-005-695; 104-809-392-055-163; 107-288-975-645-358; 111-187-508-561-376; 112-597-084-435-023; 115-367-975-737-741; 117-932-430-565-355; 125-420-212-519-87X; 125-728-532-714-579; 140-176-565-691-036; 144-993-908-462-610; 145-353-642-049-802; 149-040-025-444-303; 150-709-813-340-051; 164-051-883-714-581; 164-233-751-793-174; 195-849-671-561-090,16,true,,bronze -133-107-344-437-031,Mapping the research landscape on forest insects: bibliometric approach from 2010 to 2024,2025-04-08,2025,journal article,Discover Forests,30592666,Springer Science and Business Media LLC,,Deepak Kumar Mahanta; Tanmaya Kumar Bhoi; Ipsita Samal; J. Komal,"Abstract; This study presents a bibliometric analysis of forest insect research from 2010 to 2024, utilizing a dataset of 12,822 publications extracted from 2319 journals. The annual growth rate of publications was 4.43%, with an average citation impact of 19.39 per article. The highest research output was recorded in 2021 (1144 articles), followed by a slight decline in subsequent years. Key contributing authors included Jactel H (78 publications, 14.56 fractionalized score), JR (75, 12.70), and Liebhold AM (58, 13.59). Institutional analysis revealed that the USDA Forest Service (385 publications), Beijing Forestry University (351), and the Swedish University of Agricultural Sciences (341) were the leading research institutions. Keyword co-occurrence analysis identified Climate change as the most frequently occurring term, indicating its central role in forest entomology research. Network analysis revealed strong collaborative linkages, with Liebhold AM and Raffa KF emerging as key influencers. Geographic distribution analysis indicated that China, the United States, Germany, and Brazil were the most significant contributors, with the United States serving as the primary hub for international research collaborations. Thematic evolution analysis showed a transition from ecological and taxonomic studies (2010–2015) to the integration of advanced methodologies, including remote sensing and machine learning for forest pest management (2021–2024). These findings provide insights into research trends, knowledge distribution, and emerging frontiers in forest insect studies.; ; Graphical Abstract; ",1,1,,,Geography; Environmental resource management; Forestry; Environmental science,,,,,,http://dx.doi.org/10.1007/s44415-025-00005-4,,10.1007/s44415-025-00005-4,,,0,004-819-527-814-707; 013-507-404-965-47X; 013-524-854-219-241; 019-128-645-237-818; 024-013-126-381-35X; 034-732-911-805-318; 044-808-566-509-681; 046-992-864-415-70X; 047-705-026-861-825; 049-391-379-302-694; 051-647-739-244-271; 052-102-835-901-75X; 053-075-690-352-467; 062-912-057-319-217; 066-659-807-906-584; 070-665-150-453-490; 077-565-350-243-507; 090-522-823-971-354; 105-063-811-905-408; 107-276-900-991-821; 112-823-418-721-699; 114-855-131-150-218; 125-782-681-495-274; 128-483-216-035-749; 157-579-411-963-012; 163-717-151-305-901; 165-503-435-727-435; 169-174-435-023-594; 169-496-046-260-141; 175-755-698-684-055; 177-262-994-468-565; 188-911-259-300-930,0,true,cc-by,hybrid -133-262-508-605-485,"Green industrial policy as an enabler of the transition to sustainability: challenges, opportunities and policy implications for developing countries",2023-10-04,2023,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Phemelo Tamasiga; Hope Mfuni; Helen Onyeaka; El houssin Ouassou,,27,1,355,376,Industrialisation; Sustainability; Enabling; Scopus; Developing country; Industrial policy; Business; Sustainable development; Green economy; Green growth; Economic growth; Economics; Political science; International trade; Psychology; Ecology; MEDLINE; Law; Market economy; Psychotherapist; Biology,,,,,,http://dx.doi.org/10.1007/s10668-023-03952-0,,10.1007/s10668-023-03952-0,,,0,001-132-723-848-234; 002-052-422-936-00X; 002-243-562-367-402; 002-596-427-175-559; 013-507-404-965-47X; 015-301-025-048-398; 020-080-046-935-409; 020-632-636-519-627; 022-050-154-142-786; 023-439-816-595-605; 027-201-513-196-004; 029-335-182-342-535; 032-758-742-453-739; 033-499-045-408-863; 037-385-800-608-894; 039-632-536-554-222; 039-674-598-455-137; 041-534-943-519-97X; 041-748-285-262-44X; 043-063-206-486-981; 046-131-356-751-753; 049-830-304-290-483; 050-373-419-048-579; 051-796-427-031-583; 056-180-959-558-77X; 056-584-710-245-613; 060-110-039-971-60X; 061-429-427-029-924; 064-993-456-740-201; 065-444-648-240-628; 067-309-687-776-24X; 067-604-530-075-711; 076-973-311-257-785; 085-300-287-100-525; 085-396-046-400-358; 086-501-924-824-719; 093-278-553-039-66X; 096-061-214-240-715; 098-573-459-231-923; 101-531-420-111-036; 107-217-869-680-848; 107-276-900-991-821; 107-789-046-589-633; 114-791-578-625-523; 118-387-703-446-550; 119-163-307-369-323; 119-726-385-328-662; 124-463-483-905-944; 126-654-370-571-241; 128-799-857-792-011; 129-964-643-334-528; 132-161-107-431-024; 135-126-528-616-110; 135-160-604-776-837; 135-942-445-375-257; 137-128-079-291-155; 138-105-052-241-11X; 141-770-516-078-794; 143-936-693-364-687; 146-021-077-530-972; 147-205-562-995-709; 153-108-877-433-279; 161-089-512-430-031; 165-238-774-533-091; 165-789-474-451-220; 166-369-458-501-983; 171-162-772-106-706; 177-532-815-925-714,5,false,, -133-681-867-544-334,Family Business Ethics: A Literature Review and Research Agenda,2025-02-21,2025,journal article,Journal of Business Ethics,01674544; 15730697,Springer Science and Business Media LLC,Netherlands,Marcos Ferasso; Tatiana Beliaeva; Sascha Kraus; Paul Jones; Tobias Gössling,"Abstract; Ethical issues in family businesses become increasingly relevant for businesses, societies and, consequently, organization scholars which manifests in a growing number of publications in the field over the years. Considerable knowledge generated in the area needs to be systematically structured and synthesized. This study reviewed 162 articles published over the last three decades (1989–2023) to map the intellectual and conceptual structure, and future research opportunities in the family business ethics field. Co-citation analysis highlighted four main groups of scholars influencing the field. The bibliographic coupling distinguished five thematic clusters: succession, religion and goodwill, entrepreneurship and innovation, ethical dilemmas, and values and ethical behavior. Sentiment analysis revealed that scholars explored more positive than negative terms associated with family business ethics. Finally, co-occurrence network analysis suggested the emerging keywords and potential research questions, organized into five research themes, for further development of the family business ethics field.",,,,,Business ethics; Quality of Life Research; Family business; Engineering ethics; Sociology; Political science; Public relations; Business; Business administration; Medicine; Public health; Engineering; Nursing,,,,,,http://dx.doi.org/10.1007/s10551-025-05951-9,,10.1007/s10551-025-05951-9,,,0,000-598-732-909-412; 000-812-446-114-306; 001-093-697-572-983; 005-342-620-492-678; 006-577-229-490-285; 006-695-894-831-606; 008-427-974-463-796; 009-532-785-223-030; 011-437-843-203-537; 013-047-434-243-457; 013-062-844-575-88X; 013-507-404-965-47X; 013-801-121-546-678; 014-141-656-429-350; 015-215-890-668-945; 015-355-519-339-025; 015-467-871-692-182; 015-550-212-367-367; 016-791-530-770-227; 016-818-250-499-126; 017-369-083-101-779; 018-982-943-408-183; 018-983-752-930-002; 019-273-180-611-427; 020-063-273-398-071; 020-069-749-634-146; 022-351-275-229-000; 023-521-034-957-424; 023-799-336-007-535; 023-809-766-876-26X; 023-855-882-379-620; 023-929-470-191-831; 025-383-214-613-004; 025-903-854-328-419; 025-961-656-879-039; 026-739-753-532-124; 028-417-666-812-807; 028-795-221-003-191; 029-730-781-540-920; 030-325-144-966-01X; 031-823-300-834-456; 033-452-167-623-133; 034-729-522-328-338; 035-073-652-881-702; 035-155-367-821-750; 037-845-294-102-405; 038-898-605-973-116; 039-363-727-271-556; 039-747-739-452-605; 040-045-315-799-778; 041-111-058-566-760; 045-109-921-632-38X; 045-541-083-889-137; 045-754-631-412-145; 045-785-374-669-979; 045-961-475-607-195; 046-228-928-780-121; 050-057-979-181-082; 050-378-564-972-875; 050-789-477-922-059; 052-658-878-260-300; 053-802-019-852-068; 054-512-144-418-499; 057-258-868-991-256; 057-850-005-232-513; 058-013-841-764-046; 058-558-614-994-626; 060-631-710-499-094; 062-145-614-747-050; 064-400-499-357-900; 065-272-124-986-658; 066-162-471-267-200; 066-165-541-341-562; 069-106-928-491-580; 070-369-491-474-429; 074-903-271-607-560; 075-598-350-145-331; 076-466-385-589-145; 078-030-201-370-17X; 079-933-724-819-689; 080-294-980-130-298; 080-325-981-274-225; 080-933-003-540-771; 081-225-415-566-678; 084-547-784-667-520; 085-098-367-700-751; 088-368-001-978-86X; 089-280-633-930-768; 090-731-522-534-055; 091-393-229-432-874; 091-697-749-143-390; 093-028-029-863-159; 093-792-038-361-891; 100-603-573-401-580; 105-432-499-066-734; 110-483-440-612-324; 114-580-992-096-559; 114-755-526-570-235; 115-196-777-356-514; 115-838-367-382-156; 116-693-239-128-796; 119-552-307-424-563; 119-880-426-480-480; 120-597-156-020-135; 120-810-613-390-749; 121-343-797-405-058; 121-536-960-304-38X; 121-813-144-996-86X; 123-278-359-520-819; 123-691-409-000-619; 126-807-120-596-870; 128-014-077-849-598; 132-999-301-803-679; 139-071-902-854-574; 141-200-607-894-303; 141-247-067-925-102; 144-127-314-426-160; 145-136-399-088-199; 148-635-575-629-114; 149-228-754-084-402; 150-901-789-280-131; 151-643-515-640-387; 152-392-211-236-935; 154-485-632-712-958; 170-882-625-879-572; 174-152-712-171-67X; 174-851-166-995-737; 178-105-120-482-558; 193-242-387-094-807,0,true,cc-by,hybrid -133-710-399-458-178,Exploring the Contributions to Mathematical Economics: A Bibliometric Analysis Using Bibliometrix and VOSviewer,2023-11-20,2023,journal article,Mathematics,22277390,MDPI AG,,Kyriaki Tsilika,"From Cournot, Walras, and Pareto’s research to what followed in the form of marginalist economics, chaos theory, agent-based modeling, game theory, and econophysics, the interpretation and analysis of economic systems have been carried out using a broad range of higher mathematics methods. The evolution of mathematical economics is associated with the most productive and influential authors, sources, and countries, as well as the identification of interactions between the authors and research topics. Bibliometric analysis provides journal-, author-, document-, and country-level metrics. In the present study, a bibliometric overview of mathematical economics came from a screening performed in September 2023, covering the timespan 1898–2023. About 6477 documents on mathematical economics were retrieved and extracted from the Scopus academic database for analysis. The Bibliometrix package in the statistical programming language R was employed to perform a bibliometric analysis of scientific literature and citation data indexed in the Scopus database. VOSviewer (version 1.6.19) was used for the visualization of similarities using several bibliometric techniques, including bibliographic coupling, co-citation, and co-occurrence of keywords. The analysis traced the most influential papers, keywords, countries, and journals among high-quality studies in mathematical economics.",11,22,4703,4703,Scopus; Bibliographic coupling; Computer science; Citation; Bibliometrics; Citation analysis; Pareto principle; Management science; Data science; Operations research; Regional science; Sociology; Economics; Library science; Mathematics; Statistics; Political science; MEDLINE; Law,,,,,https://www.mdpi.com/2227-7390/11/22/4703/pdf?version=1700482844 https://doi.org/10.3390/math11224703,http://dx.doi.org/10.3390/math11224703,,10.3390/math11224703,,,0,002-052-422-936-00X; 002-753-681-855-767; 008-858-698-513-586; 013-507-404-965-47X; 013-629-056-856-394; 016-488-439-758-33X; 044-808-566-509-681; 046-992-864-415-70X; 048-741-281-161-345; 049-833-245-876-727; 050-620-415-061-78X; 052-001-609-824-917; 054-275-424-237-370; 057-188-814-049-301; 060-545-541-988-979; 063-401-627-636-751; 064-843-873-273-700; 064-932-988-246-336; 076-498-170-063-038; 080-385-861-859-389; 085-759-279-520-940; 086-857-397-565-790; 094-908-890-927-019; 115-946-769-361-866; 123-202-581-406-928; 139-702-939-133-891; 143-777-833-567-756; 182-612-161-312-046,15,true,cc-by,gold -134-181-543-786-906,Artificial Intelligence and Human Resources Management: A Bibliometric Analysis,2022-11-18,2022,journal article,Applied Artificial Intelligence,08839514; 10876545,Informa UK Limited,United Kingdom,P.R. Palos-Sánchez; P. Baena-Luna; A. Badicu; J.C. Infante-Moro,"Artificial Intelligence (AI) is increasingly present in organizations. In the specific case of Human Resource Management (HRM), AI has become increasingly relevant in recent years. This article aims to perform a bibliometric analysis of the scientific literature that addresses in a connected way the application and impact of AI in the field of HRM. The scientific databases consulted were Web of Science and Scopus, yielding an initial number of 156 articles, of which 73 were selected for subsequent analysis. The information was processed using the Bibliometrix tool, which provided information on annual production, analysis of journals, authors, documents, keywords, etc. The results obtained show that AI applied to HRM is a developing field of study with constant growth and a positive future vision, although it should also be noted that it has a very specific character as a result of the fact that most of the research is focused on the application of AI in recruitment and selection actions, leaving aside other sub-areas with a great potential for application.",36,1,,,Computer science; Scopus; Field (mathematics); Aside; Human resource management; Data science; Selection (genetic algorithm); Human resources; Knowledge management; Web of science; Scientific literature; Artificial intelligence; Operations research; Management; Political science; MEDLINE; Art; Paleontology; Mathematics; Literature; Pure mathematics; Law; Economics; Biology; Engineering,,,,,https://idus.us.es/bitstream/11441/139594/1/Artificial_Intelligence_and_Human_Resources_Management.pdf https://idus.us.es/handle//11441/139594,http://dx.doi.org/10.1080/08839514.2022.2145631,,10.1080/08839514.2022.2145631,,,0,000-814-512-206-700; 001-614-736-985-811; 003-812-909-748-970; 004-074-654-595-611; 004-302-385-175-417; 009-181-661-133-058; 009-629-899-214-731; 010-037-165-073-622; 010-729-316-690-810; 010-799-566-619-930; 011-089-568-802-43X; 011-239-904-175-510; 011-820-215-697-873; 012-170-569-200-662; 012-647-480-253-755; 013-507-404-965-47X; 013-913-898-424-203; 014-007-869-266-076; 014-454-353-557-352; 015-453-047-031-055; 016-348-874-888-409; 016-593-329-561-362; 021-187-695-321-390; 026-533-891-838-101; 027-068-069-021-629; 031-909-553-637-650; 034-963-396-707-438; 036-509-257-765-964; 037-485-013-513-747; 038-420-930-140-22X; 039-339-927-570-761; 048-947-832-795-322; 055-326-310-965-736; 056-894-789-016-760; 058-419-583-918-97X; 058-874-115-227-750; 060-950-326-542-105; 061-787-053-978-622; 065-987-634-640-867; 066-028-428-192-648; 069-542-233-050-122; 071-971-802-817-07X; 072-900-763-568-602; 072-963-145-141-407; 073-624-728-135-922; 073-775-823-470-313; 074-212-371-920-017; 074-749-248-434-11X; 076-889-664-094-211; 079-329-009-311-172; 080-643-194-734-089; 083-311-225-108-952; 083-589-598-006-234; 083-766-018-956-706; 084-519-044-974-906; 085-300-287-100-525; 087-322-900-555-182; 092-584-942-715-19X; 095-272-081-404-184; 096-059-185-163-374; 097-088-246-999-810; 099-780-094-104-283; 100-445-029-445-191; 100-679-169-763-863; 102-200-297-807-248; 102-694-788-795-301; 107-247-895-906-174; 113-869-983-037-857; 116-194-587-286-735; 125-956-873-193-905; 136-515-074-193-541; 137-060-241-868-146; 139-521-514-995-143; 145-059-240-052-534; 147-199-278-864-535; 152-441-453-263-256; 180-069-465-828-207; 183-301-025-334-708; 183-399-888-941-720; 189-837-124-179-153,81,true,"CC BY, CC BY-NC",gold -134-278-589-553-498,O uso do software Qblade na energia eólica: uma revisão bibliográfica,2024-10-18,2024,journal article,Revista de Gestão e Secretariado,21789010,Brazilian Journals,,Carla Freitas de Andrade; Jasson Fernandez Gurgel; Francisco Olimpio Moura Carneiro; Mona Lisa Moura de Oliveira; Tainan Sousa Viana; Lara Albuquerque Fortes; Alexandre Sales Costa,"Este artigo busca avaliar as tendências das publicações qaue utilizaram o software Qbade analisando o contexto mundial e nacional, sendo possível analisar a tendência de crescimento de artigos e periódicos nessa área em estudo, bem como os polos com maiores publicações no domínio e autores mais à frente em quantidade e citações de seus periódicos, além de outros indicadores, o que pode ajudar a nortear futuras pesquisas. Para isso, fez-se uma busca na base Scopus considerando algumas palavras-chave e fazendo a análise dos documentos através do Bibliometrix. É importante destacar a importância da análise bibliométrica pelo fato de poder ser usada como ferramenta para guiar pesquisas.",15,10,e4367,e4367,Psychology; Computer science,,,,,,http://dx.doi.org/10.7769/gesec.v15i10.4367,,10.7769/gesec.v15i10.4367,,,0,002-321-131-216-873; 003-089-334-936-283; 004-672-413-615-378; 006-564-247-336-203; 009-376-996-959-919; 012-986-178-211-163; 013-507-404-965-47X; 013-565-182-899-15X; 017-242-290-282-367; 017-516-661-338-952; 028-432-528-615-86X; 028-655-129-653-998; 029-780-982-362-281; 031-323-282-329-542; 037-161-966-425-577; 038-896-041-248-314; 039-345-928-746-563; 046-992-864-415-70X; 051-971-154-327-500; 052-509-939-255-902; 055-409-339-861-176; 062-758-717-557-26X; 073-891-875-540-57X; 074-409-467-932-257; 079-223-988-947-098; 082-871-381-056-989; 084-210-789-978-981; 085-907-183-097-350; 086-165-636-391-269; 090-245-960-097-170; 096-603-486-077-45X; 100-072-561-144-302; 106-920-765-019-017; 108-168-640-107-136; 122-680-420-332-171; 124-500-557-662-552; 127-720-786-995-258; 129-052-291-761-38X; 135-111-179-261-873; 145-210-796-881-126; 148-981-938-289-510; 154-112-075-816-882; 155-929-715-919-269; 157-067-153-621-300; 168-552-778-873-741; 175-512-015-308-485; 175-797-829-490-126; 178-788-246-165-369,0,true,cc-by-nc-nd,gold -134-595-748-214-274,Metaverse: technology landscape of patent informations,2023-06-20,2023,conference proceedings article,2023 18th Iberian Conference on Information Systems and Technologies (CISTI),,IEEE,,Eduardo Amadeu Dutra Moresi; Isabel Pinho; António Pedro Costa,"Technically, the metaverse is a shared virtual collective space created by converging virtually enhanced physical and digital reality. As a combinatorial innovation, multiple technologies and trends are required, such as virtual reality, augmented reality, the internet of things, 5G, and artificial intelligence. The objective of this paper is to present a landscape of the technologies registered in patent documents using the R Bibliometrix package to explore the metadata retrieved in the research. The methodology of this work comprises the data collection, detailing how the study was carried out, and the analysis of the patent metadata using the R-Bibliometrix package. The technology landscape contained the performance and technological structure analyses. The performance indicators identified patents by jurisdiction and top applicants. The technological structure presented the following topics: the most frequent words and CPC/subclass codes; trend topics; thematic map and evolution of the CPC/group codes. The conclusion highlights the use of R-Bibliometrix for the development of a technological landscape.",,,1,6,Metadata; Computer science; Metaverse; Data science; Virtual reality; World Wide Web; The Internet; Intellectual property; Encyclopedia; Space (punctuation); Augmented reality; Human–computer interaction; Library science; Operating system,,,,,,http://dx.doi.org/10.23919/cisti58278.2023.10211453,,10.23919/cisti58278.2023.10211453,,,0,,0,false,, -135-379-546-640-857,"Responsabilidad social, un estudio bibliométrico",2021-11-16,2021,journal article,CAPIC REVIEW,07184662; 07184654,Capic Review,,Jorge Sánchez Henríquez; Ignacio Vidal,"El propósito de este artículo es presentar un análisis bibliométrico de la producción científica sobre Responsabilidad Social. Los artículos fueron procesados con MSExcel, Bibliometrix y VosViewer. La producción se concentró en negocios, administración, contabilidad, ciencias sociales y economía, el tema más recurrente fue el rendimiento financiero y la productividad, el desarrollo conceptual se concentró en pocas revistas, la mayoría de la productividad se asoció a solo tres autores principales, los cuales tienen casi la totalidad de las publicaciones y concentran la mayor cantidad de citaciones. Esto se replicó a nivel de continentes y países, lo cual se debería revertir en el futuro.",19,,1,16,,,,,,https://capicreview.com/index.php/capicreview/article/download/125/76,http://dx.doi.org/10.35928/cr.vol19.2021.125,,10.35928/cr.vol19.2021.125,3217308693,,0,,1,true,cc-by-nc-sa,gold -135-468-293-524-966,Comprehensive bibliometric mapping of publication trends in the development of Building Sustainability Assessment Systems,2020-06-02,2020,journal article,"Environment, Development and Sustainability",1387585x; 15732975,Springer Science and Business Media LLC,Netherlands,Nina Lazar; K. Chithra,,23,4,4899,4923,Political science; Systematic review; Online database; Citation; Green building; Bibliometric analysis; Sustainable development; Knowledge management; Sustainability; Scopus,,,,,https://ideas.repec.org/a/spr/endesu/v23y2021i4d10.1007_s10668-020-00796-w.html https://pubag.nal.usda.gov/catalog/7337767 https://link.springer.com/article/10.1007/s10668-020-00796-w,http://dx.doi.org/10.1007/s10668-020-00796-w,,10.1007/s10668-020-00796-w,3033463989,,0,003-240-508-240-526; 003-569-624-960-639; 003-816-851-490-214; 006-711-803-693-656; 010-445-467-236-370; 011-231-049-242-148; 012-152-687-942-158; 013-507-404-965-47X; 013-916-155-553-489; 014-125-879-081-929; 014-619-603-700-645; 014-990-650-069-733; 015-469-126-769-193; 016-470-524-425-104; 016-595-868-301-112; 017-186-027-942-205; 018-984-532-738-638; 022-294-190-851-089; 025-686-894-799-831; 026-527-514-351-487; 027-597-137-549-26X; 033-712-489-419-862; 033-907-182-910-366; 037-724-072-093-40X; 038-471-678-825-453; 040-392-851-490-72X; 043-065-680-858-913; 043-614-773-400-775; 043-812-078-798-870; 046-078-316-518-519; 048-738-030-661-030; 049-768-019-209-709; 052-012-505-191-514; 052-432-692-757-632; 054-263-635-144-096; 054-514-698-610-844; 057-176-919-408-157; 057-859-555-796-728; 058-650-276-710-927; 069-717-990-927-157; 073-895-710-120-68X; 076-663-159-401-602; 082-457-788-389-079; 084-503-572-647-259; 085-503-126-035-814; 087-124-133-541-910; 091-017-486-029-462; 094-486-714-611-86X; 096-406-687-580-85X; 097-771-924-943-880; 099-484-068-493-266; 099-779-692-904-960; 106-043-361-843-307; 106-480-552-573-712; 109-386-080-905-19X; 109-829-000-787-614; 112-451-243-249-462; 114-180-170-021-694; 118-953-581-544-50X; 120-240-257-392-518; 124-573-515-944-583; 132-777-837-807-121; 137-792-274-451-121; 148-097-713-099-84X; 149-101-989-315-377; 149-774-196-530-92X; 164-614-676-169-425; 180-920-866-633-60X; 181-276-998-438-138; 195-697-366-778-605; 196-718-158-384-958,51,false,, -135-591-741-851-770,Helix innovation models: systematic literature review with data analysis script by R software and ChatGPT,2024-12-04,2024,journal article,Quality & Quantity,00335177; 15737845,Springer Science and Business Media LLC,Netherlands,Andréa Aparecida da Costa Mineiro; Victor Eduardo de Mello Valério; Isabel Cristina da Silva Arantes; Sandra Miranda Neves; Rita de Cassia Arantes,,59,2,1353,1381,Software; Systematic review; Computer science; Data science; Programming language; Political science; MEDLINE; Law,,,,,,http://dx.doi.org/10.1007/s11135-024-02012-7,,10.1007/s11135-024-02012-7,,,0,001-898-782-078-187; 003-554-382-116-811; 004-699-636-302-547; 008-016-846-441-06X; 013-507-404-965-47X; 018-149-831-140-768; 022-290-383-425-731; 027-195-243-194-261; 034-736-718-645-023; 039-343-784-548-621; 043-961-566-380-149; 067-371-738-936-897; 079-384-320-708-764; 081-547-256-855-879; 094-913-369-084-870; 095-292-974-959-45X; 102-458-672-600-731; 110-104-719-683-178; 120-094-718-338-889; 121-910-172-980-456,0,false,, -135-726-270-147-685,Bibliometrix Application on Halal Tourism Management Research,2022-12-09,2022,journal article,Journal of Islamic Economic Literatures,27754251,Sharia Economic Applied Research and Training (SMART) Insight,,Sabiq Al Qital,"This research aims to find out and map research related to the development of Halal Tourism Management research trends published by leading journals on Halal Tourism Management policy. The analysis focused on describing the characteristics and trends of the keywords, authors, and journals. The data analyzed were from 191 research publications in Scopus. The search terms were “Halal Tourism Management”. The searches used to establish the study dataset were last updated on May 11, 2022. Descriptive statistical methods were used, and a bibliometric analysis was conducted using Biblioshiny, an R-based app, to generate a bibliometric map. This study has found that the basic themes of this topic are ""Travelers Destinations Countries"", ""Muslim Tourists Destinations"", and ""Halal Tourism Indonesia"". And the destination countries for halal tourism are not only Muslim countries, but there are non-Muslim countries that are developing halal tourism management such as; Japan, North Korea, Australia, and Thailand. The originality offered by this research is the use of the biblioshiny analysis tool by the R  program.The limitations of this research include the time for data analysis is not long enough. The findings of this study can provide insight for regulators and academics to develop marketing strategies and management of halal tourism.",3,2,,,Tourism; Originality; Scopus; Descriptive statistics; Destinations; Marketing; Tourist destinations; Hospitality management studies; Destination management; Business; Geography; Political science; Sociology; Qualitative research; Social science; Statistics; Mathematics; Archaeology; MEDLINE; Law,,,,,http://journals.smartinsight.id/index.php/JIEL/article/download/122/116 https://doi.org/10.58968/jiel.v3i2.122,http://dx.doi.org/10.58968/jiel.v3i2.122,,10.58968/jiel.v3i2.122,,,0,,1,true,,bronze -135-902-004-344-07X,Agricultural Greenhouse Gas Emission Topic Clustering Based on Keyword Co-occurrence Analysis,2021-12-29,2021,conference proceedings article,"Proceedings of the 2021 4th International Conference on E-Business, Information Management and Computer Science",,ACM,,Li Tingxuan,"Greenhouse gas emission is widely known as the biggest culprit of climate change on earth. Emissions from agricultural sector, as the second greatest greenhouse gas emission source, has received increasing attention. In order to find the research hotspots and frontiers of this area, a bibliometric analysis was conducted and visualized using bibliometrix package of R and VOSviewer software based on co-word analysis. 1133 research papers were collected from Web of Science database from 2011 to 2020. During the last decades, we saw a continuous increase in the number of publications. China published the highest number of documents which accounts for 30% of total publications, followed by USA and German with proportions of 10% and 7.6% respectively. 2529 key words were identified, cluster analysis was conducted based on the co-occurrence of these terms. The result of this study may reveal the research hotspots and frontiers of this area.",,,310,316,Greenhouse gas; Agriculture; Cluster analysis; China; German; Environmental science; Cluster (spacecraft); Computer science; Database; Data science; Geography; Archaeology; Ecology; Machine learning; Biology; Programming language,,,,,,http://dx.doi.org/10.1145/3511716.3511763,,10.1145/3511716.3511763,,,0,004-031-632-238-218; 005-394-809-940-272; 014-791-596-345-888; 027-059-338-389-006; 027-133-096-818-025; 043-569-104-773-734; 054-714-544-360-033; 073-751-178-141-333; 156-415-541-949-588; 159-306-125-917-84X,0,false,, -135-935-434-950-134,Business Intelligence Management with Artificial Intelligence for Prediction Information Technology Infrastructure in Higher Education,2025-05-27,2025,journal article,TEM Journal,22178333; 22178309,Association for Information Communication Technology Education and Science (UIKTEN),,Warunee Milinthapunya; Urairat Yamchuti; Anake Nammakhunt; Chatchada Shawarangkoon; Panita Wannapiroon; Prachyanun Nillsook,"This study uses a mixed-methods research approach, combining meta-analysis and systematic Bibliometrix analysis, to explore the use of Business Intelligence (BI) and Artificial Intelligence (AI) in predicting Information Technology (IT) infrastructure in higher education institutions. The synergy between BI and AI serves as a key tool for evaluating and forecasting IT infrastructure, supporting decision-making and strategic IT planning in universities. This research develops predictive models for IT infrastructure investments using BI and AI, ensuring efficient resource allocation and enhancing university decision-making, aligned with the evolving digital landscape in higher education.",,,1378,1387,,,,,,,http://dx.doi.org/10.18421/tem142-38,,10.18421/tem142-38,,,0,,0,false,, -136-112-764-815-006,"A bibliometric analysis of research on R-loop: Landscapes, highlights and trending topics.",2023-04-14,2023,journal article,DNA repair,15687856; 15687864,Elsevier BV,Netherlands,Ran Li; Bo Liu; Xianglin Yuan; Zuhua Chen,"R-loop is a necessary intermediate in specific cellular processes. To profile the landscapes, highlights, and trending topics of R-loop, publications related to R-loop from 1976 to 2022 were downloaded and bibliometric analyses were performed by Bibliometrix in R and VOSviewer. 1428 documents (including 1092 articles and 336 reviews) were included. USA, United Kingdom, and China contributed more than one-third of the publications. The annual publication increased rapidly since 2010. The research trend of R-loop has evolved from the discovery of phenomena to the exploration of molecular mechanisms, from the elucidation of biological functions to the analysis of disease correlations. Ongoing roles of R-loop in DNA repair process was highlighted and further analyzed. This study may accelerate R-loop research by highlighting important researches, understanding the trending topic, and integrating with other areas.",127,,103502,103502,Biology; Bibliometrics; China; Loop (graph theory); Library science; Data science; Regional science; Computer science; Sociology; Archaeology; Geography; Mathematics; Combinatorics,Bibliometric analysis; DNA repair; Disease; R-loop,R-Loop Structures; Bibliometrics; DNA Repair,,National Natural Science Foundation of China,,http://dx.doi.org/10.1016/j.dnarep.2023.103502,37099848,10.1016/j.dnarep.2023.103502,,,0,001-584-195-182-287; 002-052-422-936-00X; 004-647-794-912-573; 014-129-634-820-525; 021-701-631-394-434; 022-866-655-368-208; 023-349-245-439-887; 025-824-143-908-307; 034-190-819-128-744; 041-054-647-591-544; 042-872-994-602-050; 043-070-736-939-621; 050-867-530-478-681; 060-875-773-924-052; 069-939-003-180-891; 071-878-836-294-733; 072-832-426-963-271; 093-014-365-908-11X; 096-590-189-535-08X; 100-780-082-852-448; 114-098-173-426-985; 134-626-280-978-365; 146-745-212-278-583; 196-493-992-788-175,5,true,cc-by,hybrid -136-202-884-993-025,Bibliometric Analysis of Research Trends in Geopolymers,2023-09-26,2023,book chapter,Geopolymers,,CRC Press,,Dumitru Doru Burduhos-Nergis; Petrica Vizureanu; Andrei Victor Sandu; Rafiza Abdul Razak; Romisuhani Ahmad,"Geopolymers are inorganic materials generated by the chemical reaction of an aluminosilicate precursor with an alkaline or acidic activator. These materials are considered to be a green, innovative alternative binder to ordinary Portland cement for long-term infrastructure development. Despite the fact that there have been a few reviews and bibliometric studies on geopolymer, none of them have employed geopolymer in the wide sense of search strings that provide a greater number of bibliographic data to give an unbiased and less subjective picture of trends and changes. Currently, there is no clear picture as to which aspects of geopolymer research are advanced and which ones are not. Therefore, this chapter will present the beginning, trends, and progress of the most relevant studies published in the field of geopolymers. The bibliometric analysis of the literature provides important statistical insights into geopolymers' development and use in the industry, emphasizing current and future research trends. As a result, in this chapter, a brief presentation of the research evolution of publications, indexed by the Scopus database, in the field of geopolymers was conducted using Bibliometrix software. The Bibliometrix software, on the other hand, can do bibliometric analysis and create data matrices for co-citation, coupling, scientific cooperation analysis, and co-word analysis. Furthermore, at the intersections of structural and temporal evolution, such as network analysis, factorial analysis, and theme mapping, new information emerges. To retrieve the data from the database, one analysis was done for the term ""geopolymer,"" which is the most general keyword used to describe the geopolymer field. The Scopus database states that at the time of inquiry, a search for ""geopolymer"" yields 10,583 results from all publications indexed in Scopus. This study's bibliometric findings may be used by academics and policymakers to share research skills, collaborate on unique geopolymer research, and form creative collaborative ventures.",,,1,17,Computer science,,,,,,http://dx.doi.org/10.1201/9781003390190-1,,10.1201/9781003390190-1,,,0,,0,false,, -136-271-520-821-395,Blockchain-Based Land Management for Sustainable Development,2022-08-26,2022,journal article,Sustainability,20711050,MDPI AG,Switzerland,Ivana Racetin; Jelena Kilić Pamuković; Mladen Zrinjski; Marina Peko,"In recent years, many papers have been published on the topics of the blockchain (BC) and blockchain technology (BCT). Some papers put BCT in the context of land registries (LRs), land cadastres (LCs), land registration, land administration (LA) and land management (LM) and its implementation benefits. Some eight years later, from its beginnings in 2014, the question of the future of the proposed concept and whether it has one, has been raised. The Scopus database was analysed using bibliometric analysis methodology and Rstudio software with the Bibliometrix R-package and the Shiny package environment. Based on this research, significant interest and growth in the topic was found in both technical and land-governance directions. Different approaches to the topic have been established in the global north and global south. From today’s perspective, the future of BCT in both worlds is guaranteed.",14,17,10649,10649,Scopus; Land administration; Context (archaeology); Sustainable land management; Land management; Land registration; Corporate governance; Land use; Environmental resource management; Geography; Regional science; Data science; Computer science; Environmental planning; Business; Political science; Land tenure; Engineering; Economics; Civil engineering; MEDLINE; Archaeology; Finance; Law; Agriculture,,,,,https://www.mdpi.com/2071-1050/14/17/10649/pdf?version=1661758396 https://doi.org/10.3390/su141710649,http://dx.doi.org/10.3390/su141710649,,10.3390/su141710649,,,0,005-182-260-619-793; 008-190-456-019-596; 011-433-487-944-268; 011-655-155-488-132; 012-357-133-859-538; 013-507-404-965-47X; 018-541-770-775-407; 027-513-615-010-760; 028-711-586-910-72X; 031-126-823-255-791; 038-287-451-734-098; 038-543-782-118-273; 047-515-894-193-882; 071-337-153-440-605; 075-567-136-878-735; 083-860-858-902-680; 094-636-017-270-896; 100-670-143-750-30X; 103-670-843-690-423; 105-400-084-388-399; 144-285-231-485-820; 147-980-806-426-316; 151-358-521-096-979,10,true,,gold -136-687-252-212-911,Risk factors for endometrial polyps to transform into endometrial cancer: insights from a bibliometric analysis.,2025-03-29,2025,journal article,"Journal of health, population, and nutrition",20721315; 16060997,Springer Science and Business Media LLC,Bangladesh,Aijie Xie; Xian Wu; Yunyi Su; Yujian Jia; Lu Yang; Ying Liu; Wei Cheng; Yonghong Lin; Xia Yu; Xiaoqin Gan,"Endometrial polyps (EPs) are at risk of transforming into endometrial cancer (EC). Terminal EC seriously affects women's quality of life and places a heavy financial burden on families. Investigating the risk factors that influence the conversion of EPs to EC and preventing them from progressing further is crucial. This study attempts to map the features of published literature on risk factors and understand the frontiers and hotspots of that research by using bibliometric analysis.; We obtained relevant publications from 1996 to 2024 from the Web of Science Core Collection (WoSCC) on July 11, 2024. Next, CiteSpace software, the R (Version 4.3.2) package Bibliometrix, the Online Analysis Platform of Document Metrology ( http://biblimetric.com ), and a web interface for Bibliometrix were used to analyse the data.; The analysis included 90 qualifying data points concerning the risk factors for the conversion of EPs to EC. The American Journal of Obstetrics and Gynecology was the most productive publication. The authors referenced the most were Cohen I and Ferrazzi E. After removing similar keywords, the keywords that did not have a specific meaning, the remaining keywords mainly included hysteroscopy, postmenopausal women, premenopausal, therapy, diagnosis, patients receiving tamoxifen, ultrasound, and management. The long-term management of EPs has emerged as a new research hotspot, per the trend topic.; In the published literature, age, perimenopause and postmenopausal bleeding are the most frequently studied factors for the conversion of EPs to EC, also including PCOS and polyp size. Endometrial polypectomy and long-term management may be recommended for these patients.; © 2025. The Author(s).",44,1,95,,Endometrial Polyp; Medicine; Endometrial cancer; Gynecology; Polypectomy; Obstetrics and gynaecology; Obstetrics; Internal medicine; Hysteroscopy; Cancer; Colorectal cancer; Pregnancy; Colonoscopy; Biology; Genetics,Bibliometric analysis; CiteSpace; Endometrial cancer; Endometrial polyps; Risk factors,Humans; Female; Endometrial Neoplasms/pathology; Bibliometrics; Polyps/pathology; Risk Factors; Uterine Diseases/pathology,,,,http://dx.doi.org/10.1186/s41043-025-00842-1,40158135,10.1186/s41043-025-00842-1,,PMC11955144,0,006-008-257-741-133; 007-011-621-945-305; 009-194-309-429-426; 010-291-048-651-247; 012-588-948-312-603; 015-859-707-754-559; 019-250-601-936-587; 023-323-281-448-443; 024-745-743-866-129; 025-528-087-226-259; 025-681-673-779-754; 027-954-942-599-246; 031-370-016-884-350; 033-116-296-055-07X; 038-791-619-373-226; 041-439-858-359-494; 048-387-554-742-470; 051-073-390-301-535; 055-048-246-710-124; 057-688-289-675-523; 063-813-411-558-863; 064-780-260-632-584; 067-360-307-044-893; 070-998-052-119-136; 071-500-176-520-613; 073-536-275-019-215; 073-781-229-597-195; 077-024-760-847-088; 082-430-655-021-588; 090-267-766-026-851; 092-503-511-836-101; 096-344-667-883-211; 156-882-090-560-487,0,true,"CC BY, CC0",gold -136-718-971-981-417,Bibliometric Analysis of Artificial Intelligence in Marketing: Revealing Publication Trends Using Bibliometrix R-Tool,2024-12-03,2024,book chapter,Contributions to Management Science,14311941; 2197716x,Springer Nature Switzerland,,Ibtissam Zejjari; Issam Benhayoun,,,,737,750,Data science; Library science; Computer science,,,,,,http://dx.doi.org/10.1007/978-3-031-67531-7_59,,10.1007/978-3-031-67531-7_59,,,0,003-392-296-452-174; 017-750-600-412-958; 020-661-790-460-152; 028-331-510-584-097; 029-314-091-095-417; 035-482-287-076-98X; 043-806-753-756-64X; 049-035-137-428-816; 052-710-734-648-862; 068-848-414-484-582; 068-991-479-449-843; 073-632-783-060-388; 075-227-805-962-707; 098-178-187-682-965; 100-048-540-453-835; 134-905-520-711-638; 147-784-139-915-504; 196-886-654-190-485,0,false,, -136-920-221-665-895,Sustainability in The Arctic: A Bibliometric Analysis,2024-04-19,2024,preprint,,,Research Square Platform LLC,,Fatma Ahmed; Greg Poelzer; Oscar Zapata,"Abstract;

This paper examines the literature on the Sustainability in the Arctic region, using a bibliometric analysis of 213 English-language articles published between 1980 and 2022 exploiting Bibliometrix, an R package. To find relevant literature using the Web of Science (WOS) database, we searched for documents using mesh terms based on the query of two terms, “Arctic & Sustainability”. We used the Boolean operator “AND” to combine the two terms and the Boolean operator ""OR"" to include synonyms of the terms. The articles retrieved were authored by 724 researchers, published in 98 journals, representing 132 countries, and growing at 5.08% annually. The findings reveal that a substantial portion of the Arctic sustainability literature placed significant emphasis on the examination of climate change, adaptation, and vulnerabilities affecting local communities. Furthermore, the more recent publications in this field concentrate predominantly on exploring perceptions and governance.

",,,,,Sustainability; Arctic; The arctic; Environmental resource management; Environmental planning; Environmental science; Geography; Oceanography; Ecology; Geology; Biology,,,,,https://www.researchsquare.com/article/rs-4125623/latest.pdf https://doi.org/10.21203/rs.3.rs-4125623/v1 https://link.springer.com/content/pdf/10.1007/s43621-024-00312-4.pdf https://doi.org/10.1007/s43621-024-00312-4,http://dx.doi.org/10.21203/rs.3.rs-4125623/v1,,10.21203/rs.3.rs-4125623/v1,,,0,000-659-274-610-38X; 001-280-575-367-993; 002-112-299-610-507; 007-686-932-781-817; 013-067-367-029-28X; 013-507-404-965-47X; 014-662-358-404-474; 017-750-600-412-958; 019-350-516-274-409; 024-706-940-128-529; 028-021-611-755-293; 028-292-405-887-994; 028-632-868-365-330; 028-705-313-936-712; 032-999-172-139-947; 033-383-253-891-840; 038-176-242-681-768; 039-176-706-856-738; 042-755-259-129-09X; 044-384-802-417-53X; 048-613-260-641-781; 054-159-894-171-769; 059-756-553-067-40X; 062-445-809-817-439; 066-339-933-525-835; 068-261-448-233-80X; 071-959-920-519-880; 078-273-210-723-922; 080-133-328-475-183; 081-507-744-009-35X; 083-137-544-456-89X; 094-294-301-073-390; 096-786-974-963-818; 098-279-162-885-611; 099-468-079-596-586; 101-283-143-114-350; 102-152-459-676-567; 115-704-036-075-908; 119-767-093-738-759; 127-958-092-071-907; 131-611-131-716-416; 132-499-382-960-164; 141-770-516-078-794; 145-754-191-280-905; 149-103-843-800-504; 151-056-508-990-403; 166-877-899-708-163; 181-843-261-672-147,0,true,cc-by,green -137-013-508-473-572,Teaching Spirituality in Nursing: A Bibliometric Analysis.,2025-01-18,2025,journal article,Journal of religion and health,15736571; 00224197,Springer Science and Business Media LLC,United States,Ana Afonso; Sara Sitefane; Janaína Fabri; Isabel Rabiais; Sílvia Caldeira,"The study of spirituality in nursing education has become an emerging academic field, making it important to understand its evolution using bibliometric indicators. To achieve this, a search was conducted on July 8, 2024, using the Web of Science and Scopus databases. Titles and abstracts were screened in Rayyan, and data analysis was performed using Bibliometrix and Biblioshiny in the R language. A total of two hundred thirty documents published between 1981 and 2024 were included. The United States contributed the most publications (n = 70), and Wilfred McSherry was the most prolific author, with 16 publications and the highest h-index. Nurse Education Today was the journal with the most publications. Transition themes identified include spiritual competence and spiritual care education.",64,2,716,731,Spirituality; Scopus; Competence (human resources); Bibliometrics; Nurse education; Web of science; Nursing; Psychology; Library science; Sociology; Medical education; MEDLINE; Medicine; Alternative medicine; Political science; Social psychology; Computer science; Pathology; Law,Bibliometrics; Education; Nurse; Spiritual care; Teaching,"Spirituality; Humans; Bibliometrics; Education, Nursing/methods",,Fundação para a Ciência e a Tecnologia (UIDB/04279/2020),,http://dx.doi.org/10.1007/s10943-024-02247-6,39826042,10.1007/s10943-024-02247-6,,PMC11950001,0,000-447-261-973-267; 003-512-592-847-270; 013-303-277-111-046; 013-493-621-564-563; 013-507-404-965-47X; 022-029-576-843-877; 032-856-702-692-670; 040-424-813-840-85X; 040-689-297-341-838; 053-966-817-102-422; 072-017-411-425-779; 075-539-832-993-35X; 096-097-624-235-737; 133-530-135-662-847; 150-150-967-417-627; 173-181-068-262-031,2,true,cc-by,hybrid -137-701-526-894-88X,AI-Enabled Supply Chain Management: A Bibliometric Analysis Using VOSviewer and RStudio Bibliometrix Software Tools,2025-02-28,2025,journal article,Sustainability,20711050,MDPI AG,Switzerland,Mihaela Gabriela Belu; Ana Maria Marinoiu,"Artificial intelligence (AI) is fundamentally transforming the management of supply chain activities, offering companies the opportunity to configure resilient, transparent, and sustainable supply chains. Given its importance, this paper presents aspects of the implementation of artificial intelligence in supply chain management by performing a bibliometric analysis of 400 scientific papers published between 2010 and 2024 and indexed in the Scopus database. The analysis was based on the Bibliometrix 4.4.2 and VOSviewer 1.6.19 software to identify the most important authors and journals of interest for the researched topic. Keyword co-occurrence and co-citation analyses were used to map intellectual networks and highlight themes of interest. The research results confirm the increase in scientific interest in the field of applying AI in supply chain management, highlighting the advantages of implementing this technology in supply chain management. At the same time, the recommendations and conclusions of this paper will be useful to both academic researchers and business professionals to identify potential areas of collaboration with the aim of developing supply chain strategies that contribute to the competitiveness of companies that are part of the network.",17,5,2092,2092,Software; Computer science; Supply chain management; Supply chain; Engineering; Manufacturing engineering; Systems engineering; Business; Operating system; Marketing,,,,,,http://dx.doi.org/10.3390/su17052092,,10.3390/su17052092,,,0,000-735-935-494-403; 002-052-422-936-00X; 002-551-375-977-226; 007-119-124-971-750; 008-896-804-617-870; 011-934-866-378-871; 013-762-910-891-248; 019-605-152-511-89X; 021-052-448-876-77X; 021-397-329-151-497; 023-877-150-230-668; 027-003-010-358-051; 037-112-168-972-727; 044-797-564-723-034; 045-375-970-005-640; 046-391-057-701-319; 047-866-972-657-967; 047-880-931-696-928; 049-268-058-973-864; 056-792-358-329-805; 056-815-391-390-762; 062-397-274-896-623; 063-233-158-964-102; 065-038-725-118-789; 066-772-579-907-837; 071-483-605-265-365; 072-653-568-418-662; 072-974-520-873-188; 077-571-063-166-597; 084-874-340-312-516; 090-476-974-003-890; 091-088-568-074-273; 091-676-512-202-089; 094-495-735-884-749; 099-286-537-166-085; 099-548-000-124-819; 100-048-540-453-835; 100-445-029-445-191; 115-481-824-746-148; 116-586-099-071-017; 118-988-341-743-251; 122-476-020-650-658; 129-041-375-674-060; 129-299-942-925-742; 134-985-477-712-653; 142-844-003-728-961; 175-841-037-903-311; 184-236-573-347-655; 189-279-211-515-983; 189-466-455-736-057; 191-606-048-979-901; 192-183-625-311-130; 199-029-599-554-532,0,true,,bronze -137-716-388-517-761,Insight into coffee consumption behavior: a Bibliometrix analysis,2024-05-08,2024,book chapter,"Advances in Economics, Business and Management Research",27317854; 23525428,Atlantis Press International BV,,Xinghan Wang,"Coffee, the ubiquitous elixir of our modern world, captivates us with its potent aroma and promises of alertness.But beyond the familiar steam, lies a complex dance of motivations, preferences, and cultural nuances that fuel our consumption.This research uses bibliometrics, a powerful quantitative tool, to delve into the rich tapestry of coffee behavior, uncovering the hidden patterns and factors that shape our choices.Our journey begins with a data-driven exploration of coffee's historical arc, tracing its path from humble Ethiopian bean to a global trade commodity.We unveil how coffee houses transformed from intellectual hubs to social sanctuaries, intertwining its consumption with identity, belonging, and even national pride.Moving beyond the surface, we dissect the psychological forces driving our coffee habits, revealing the interplay between personality traits, stress levels, and sleep patterns.Socioeconomic factors are also examined, demonstrating how income, education, and occupation influence not only the quantity consumed but also brewing methods, brand choices, and social settings.Technology's ever-present influence is revealed as it democratizes access, broadens choices, and even gamifies the coffee experience through singleserve machines, coffee shop chains, and mobile apps.The digital space, with its online communities and influencer trends, sheds light on how social media shapes our coffee preferences and consumption habits.We navigate the ongoing debate surrounding coffee's health effects, examining the interplay between demonization and celebration, revealing how consumer choices evolve with scientific dialogue.Finally, we peer into the future, gazing at emerging trends and innovations in coffee consumption.Sustainable practices, ethical sourcing, and personalized brewing experiences are just a glimpse into the future of our relationship with this beloved beverage.By analyzing the research landscape, we aim to identify the forces driving these innovations and predict their potential impact.This research is not merely a statistical analysis; it's a quest to understand ourselves, our societies, and the intricate web of factors that bind us to this seemingly simple cup.By harnessing the power of bibliometrics, we hope to unveil not just the data-driven insights but also the cultural essence, the psychological nuances, and the human stories that lie at the heart of coffee consumption.So, brew a cup of curiosity, settle in, and join us on this journey into the data-rich world of coffee behavior.Together, we may just discover that the aroma of a perfect cup holds a universe of understanding.",,,104,112,Consumption (sociology); Psychology; Art; Aesthetics,,,,,https://www.atlantis-press.com/article/125999626.pdf https://doi.org/10.2991/978-94-6463-408-2_13,http://dx.doi.org/10.2991/978-94-6463-408-2_13,,10.2991/978-94-6463-408-2_13,,,0,,0,true,cc-by-nc,hybrid -137-823-750-024-083,Global trends and research hotspots in nanodrug delivery systems for breast cancer therapy: a bibliometric analysis (2013-2023).,2025-03-06,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Yang Li; Pingping Liu; Bo Zhang; Juan Chen; Yuanyuan Yan,"Nanomedicine offers fresh approaches for breast cancer treatment, countering traditional limitations. The nanodrug delivery system's precision and biocompatibility hold promise, yet integration hurdles remain. This study reviews nano delivery systems in breast cancer therapy from 2013 to 2023, guiding future research directions.; In this study, we conducted a comprehensive search on Web of Science database (Guilin Medical University purchase edition) and downloaded literature related to the field published between 2013 and 2023. We analyzed these publications using R software, VOSviewer, and CiteSpace software.; This study reviewed 2632 documents, showing a steady publication increase from 2013 to 2023, peaking at 408 in 2022. China, USA, India, and Iran were prominent in publishing. The Chinese Academy of Sciences and Tabriz University of Medical Science were key collaboration centers. Notably, the Journal of Controlled Release and Biomaterials ranked among the top 10 journals for publications and citations, establishing their field representation. Key terms like ""breast cancer,"" ""nanoparticles,"" ""drug delivery,"" ""in-vitro,"" and ""delivery"" were widely used. Research focused on optimizing drug targeting, utilizing the tumor microenvironment for drug delivery, and improving delivery efficiency.; The nanodrug delivery system, as an innovative drug delivery approach, offers numerous advantages and has garnered global attention from researchers. This study provides an analysis of the status and hotspots in nano delivery systems within the realm of breast cancer therapy, offering valuable insights for future research in this domain.; © 2025. The Author(s).",16,1,269,,Breast cancer; Drug delivery; Medicine; Web of science; Cancer; Nanotechnology; Internal medicine; Meta-analysis; Materials science,Bibliometrics; Breast cancer; Nanodrug delivery system; Target; Tumor microenvironment,,,,,http://dx.doi.org/10.1007/s12672-025-02014-3,40047951,10.1007/s12672-025-02014-3,,PMC11885776,0,000-096-142-707-44X; 003-672-447-735-38X; 005-471-918-175-473; 005-706-968-934-128; 006-707-013-942-986; 008-225-183-326-79X; 012-781-487-452-738; 013-211-554-248-756; 014-247-009-069-702; 016-205-704-340-274; 017-918-545-739-814; 019-921-582-503-747; 020-719-013-507-779; 021-852-090-804-733; 023-022-732-525-833; 028-486-185-670-472; 029-969-996-130-704; 030-899-129-026-17X; 032-605-511-425-039; 039-311-157-558-568; 041-436-885-153-076; 042-730-226-334-264; 045-777-896-383-118; 046-125-991-452-516; 049-576-210-535-91X; 050-456-242-751-341; 055-366-674-866-84X; 061-131-002-762-854; 061-939-405-344-296; 065-138-497-606-93X; 065-556-695-469-886; 067-697-467-605-585; 067-716-466-790-10X; 069-851-826-021-633; 070-659-175-226-891; 076-549-989-149-830; 079-040-840-157-266; 083-045-044-642-997; 084-039-198-089-042; 085-456-360-064-016; 086-856-314-652-182; 087-568-411-131-696; 090-476-872-676-699; 091-000-534-012-85X; 096-886-043-581-035; 100-143-263-146-217; 102-048-052-208-753; 103-234-393-442-869; 106-367-948-213-532; 107-483-302-885-238; 108-519-330-850-508; 113-001-523-324-402; 119-150-592-078-898; 121-191-664-124-631; 122-742-966-518-614; 138-177-804-876-760; 147-620-482-195-451; 151-143-379-379-100; 156-968-799-254-978; 171-567-208-740-55X; 173-324-405-825-380; 183-058-231-518-703; 189-040-318-256-315,0,true,cc-by,gold -137-945-212-435-964,Virtual Campus: bibliometrix: An R-Tool for Bibliometric Analysis,2020-03-26,2020,,,,,,Thierry Warin,,,,,,Engineering; World Wide Web; Virtual campus; Bibliometric analysis,,,,,https://virtualcampus.skemagloballab.io/posts/bibliometrix/,https://virtualcampus.skemagloballab.io/posts/bibliometrix/,,,3024976264,,0,,0,false,, -138-592-609-593-587,A bibliometric review on electric vehicle (EV) energy efficiency and emission effect research.,2023-08-19,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Shengyong Yao; Zixiang Bian; Mohammad Kamrul Hasan; Ru Ding; Shuning Li; Yanfei Wang; Shulei Song,,30,42,95172,95196,Efficient energy use; Thematic map; Electric vehicle; Automotive engineering; Environmental economics; Computer science; Environmental science; Engineering; Electrical engineering; Physics; Power (physics); Cartography; Quantum mechanics; Economics; Geography,Bibliometrics analysis; Carbon dioxide; Electric vehicle; Emission reduction; Energy efficiency,Bibliometrics; Commerce; Conservation of Energy Resources; Electricity,,key project of science and technology research project of colleges and universities in Hebei Province (ZD2021094),,http://dx.doi.org/10.1007/s11356-023-29143-y,37596481,10.1007/s11356-023-29143-y,,,0,002-052-422-936-00X; 006-141-203-157-655; 006-635-907-630-99X; 007-488-419-392-143; 008-381-180-356-314; 013-507-404-965-47X; 014-081-110-525-859; 015-780-396-023-350; 016-325-881-412-415; 016-780-572-888-22X; 017-492-231-797-16X; 022-961-686-628-397; 024-621-087-835-353; 026-753-809-866-774; 027-273-939-541-680; 027-408-163-010-246; 029-101-516-541-242; 029-420-167-353-195; 030-832-686-066-661; 031-990-938-112-725; 034-837-297-465-114; 038-724-537-986-520; 042-365-872-678-835; 042-365-939-090-826; 044-366-322-607-191; 046-992-864-415-70X; 047-861-098-835-225; 048-722-594-293-476; 050-136-003-411-574; 050-664-965-270-417; 053-494-071-710-268; 055-437-980-183-786; 057-145-369-099-326; 060-938-726-800-730; 074-663-084-636-454; 075-000-429-187-674; 077-781-495-297-414; 085-300-287-100-525; 085-591-833-146-540; 089-701-212-152-294; 091-883-752-596-787; 093-167-525-489-194; 094-467-282-909-617; 095-039-979-917-137; 097-595-861-965-600; 101-752-490-869-458; 112-299-111-380-385; 114-448-714-354-062; 120-543-583-112-970; 120-861-012-740-803; 138-450-996-891-440; 160-071-542-803-167; 165-396-690-357-717; 167-921-029-604-178; 168-890-633-354-205; 182-001-698-412-845; 183-985-001-161-89X,10,false,, -138-991-403-049-285,Mapping the field of behavioural biases: a literature review using bibliometric analysis,2021-03-25,2021,journal article,Management Review Quarterly,21981620; 21981639,Springer Science and Business Media LLC,,Jinesh Jain; Nidhi Walia; Simarjeet Singh; Esha Jain,,72,3,823,855,,,,,,,http://dx.doi.org/10.1007/s11301-021-00215-y,,10.1007/s11301-021-00215-y,,,0,000-782-460-541-246; 000-928-764-998-068; 001-597-651-848-71X; 002-532-758-320-404; 005-465-266-840-35X; 005-553-153-856-945; 006-122-212-375-634; 006-750-012-058-578; 006-930-359-061-678; 007-246-121-722-005; 008-031-071-054-19X; 008-250-861-392-767; 008-688-112-207-524; 008-703-444-296-132; 009-544-888-475-722; 009-785-738-009-66X; 010-286-095-148-779; 010-860-882-323-912; 011-223-654-787-20X; 011-654-983-120-179; 011-844-580-813-816; 012-965-640-300-869; 013-646-776-133-041; 013-770-623-528-921; 014-576-901-288-057; 014-954-601-101-444; 015-169-522-476-160; 017-042-951-623-899; 017-750-600-412-958; 018-705-396-346-570; 021-086-133-082-399; 021-363-528-460-81X; 021-431-342-626-633; 021-699-787-150-241; 021-806-720-154-089; 022-009-191-637-070; 024-491-347-287-793; 025-099-557-966-719; 025-139-489-059-239; 025-471-939-534-338; 026-007-289-506-85X; 026-546-111-551-568; 027-005-239-427-149; 027-379-234-180-438; 027-654-829-018-118; 028-716-381-632-159; 029-610-711-905-385; 032-270-746-189-390; 032-914-674-109-451; 035-663-708-024-858; 036-227-401-844-443; 036-378-196-049-974; 036-436-321-202-708; 038-631-624-874-022; 040-561-748-236-832; 040-761-282-497-956; 040-896-549-114-749; 042-746-635-197-017; 044-135-826-839-262; 044-193-335-211-417; 045-773-388-008-014; 046-868-031-785-29X; 047-134-478-431-993; 048-889-551-897-67X; 050-242-194-449-389; 050-864-757-436-458; 051-448-485-398-729; 052-040-388-869-610; 052-733-656-678-856; 053-668-229-607-517; 055-794-847-486-505; 056-373-100-564-326; 058-795-508-255-191; 058-805-263-634-244; 058-930-171-825-636; 061-535-666-990-826; 061-617-556-097-163; 062-197-008-437-639; 063-689-408-969-471; 064-082-736-992-676; 064-264-695-662-36X; 064-615-403-779-77X; 067-340-425-284-638; 068-401-600-730-74X; 069-758-661-058-369; 070-268-534-139-303; 070-388-076-993-102; 072-856-861-900-730; 075-227-805-962-707; 075-301-866-096-796; 077-444-269-577-533; 078-073-570-782-17X; 078-896-662-324-616; 079-278-714-415-834; 079-578-018-214-320; 080-044-528-940-073; 080-724-759-730-013; 081-329-954-412-076; 082-708-592-027-846; 082-784-141-450-279; 083-050-484-558-189; 083-311-225-108-952; 085-300-287-100-525; 085-905-526-143-293; 087-500-813-525-996; 088-380-511-219-726; 089-376-060-537-606; 089-858-491-923-543; 090-541-956-888-654; 091-750-234-259-060; 093-626-693-418-440; 095-775-618-061-340; 096-262-761-890-304; 098-604-150-858-997; 098-726-748-134-913; 103-972-765-801-266; 109-172-925-539-934; 109-847-052-074-690; 111-911-102-968-883; 114-152-899-878-408; 118-026-234-386-896; 120-277-042-127-572; 127-803-129-644-70X; 127-902-838-470-080; 132-794-914-127-192; 133-339-344-151-677; 134-215-353-761-225; 142-221-289-294-474; 142-423-007-855-663; 147-947-151-500-006; 149-449-384-202-908; 149-679-844-296-567; 149-825-286-523-560; 151-670-586-644-047; 157-518-278-327-447; 157-843-245-427-790; 159-382-288-612-420; 160-099-577-674-523; 160-335-288-157-679; 162-719-879-348-608; 163-822-439-259-814; 173-685-603-301-549; 185-091-195-579-038; 185-583-432-618-274; 190-624-303-228-420; 194-327-828-636-077; 196-880-385-193-583,73,false,, -138-996-986-146-361,Deepfakes: evolution and trends,2023-06-15,2023,journal article,Soft Computing,14327643; 14337479,Springer Science and Business Media LLC,Germany,Rosa Gil; Jordi Virgili-Gomà; Juan-Miguel López-Gil; Roberto García,"AbstractThis study conducts research on deepfakes technology evolution and trends based on a bibliometric analysis of the articles published on this topic along with six research questions: What are the main research areas of the articles in deepfakes? What are the main current topics in deepfakes research and how are they related? Which are the trends in deepfakes research? How do topics in deepfakes research change over time? Who is researching deepfakes? Who is funding deepfakes research? We have found a total of 331 research articles about deepfakes in an analysis carried out on the Web of Science and Scopus databases. This data serves to provide a complete overview of deepfakes. Main insights include: different areas in which deepfakes research is being performed; which areas are the emerging ones, those that are considered basic, and those that currently have the most potential for development; most studied topics on deepfakes research, including the different artificial intelligence methods applied; emerging and niche topics; relationships among the most prominent researchers; the countries where deepfakes research is performed; main funding institutions. This paper identifies the current trends and opportunities in deepfakes research for practitioners and researchers who want to get into this topic.",27,16,11295,11318,Scopus; Bibliometrics; Trend analysis; Data science; Computer science; Political science; Library science; MEDLINE; Machine learning; Law,,,,,https://link.springer.com/content/pdf/10.1007/s00500-023-08605-y.pdf https://doi.org/10.1007/s00500-023-08605-y,http://dx.doi.org/10.1007/s00500-023-08605-y,,10.1007/s00500-023-08605-y,,,0,000-309-193-839-238; 000-761-184-611-339; 001-388-465-808-65X; 001-587-905-907-259; 001-602-649-497-141; 002-110-477-654-336; 002-251-139-349-741; 003-540-510-238-024; 003-939-876-924-410; 003-978-044-605-558; 004-252-010-348-067; 004-369-871-251-506; 005-059-754-409-629; 005-542-622-329-141; 005-813-910-751-664; 006-608-357-128-458; 006-779-782-656-573; 007-090-497-023-677; 007-095-593-886-678; 007-165-519-613-082; 007-392-723-533-629; 008-452-323-309-730; 008-926-062-964-201; 008-985-439-018-136; 009-259-115-633-976; 010-379-974-018-041; 010-482-919-152-251; 011-186-978-226-230; 012-270-616-433-871; 012-484-052-671-527; 012-506-288-948-988; 012-873-547-694-885; 013-059-596-824-551; 013-425-449-378-755; 013-507-404-965-47X; 013-517-421-708-546; 013-777-271-530-615; 014-012-098-508-124; 014-218-263-420-462; 014-337-489-189-787; 014-488-031-898-301; 014-740-963-773-770; 015-024-936-268-583; 015-135-161-777-682; 015-284-637-643-348; 016-111-102-154-266; 016-153-620-434-124; 016-281-010-684-261; 016-307-931-064-73X; 017-382-848-609-942; 017-647-797-564-537; 019-144-038-182-624; 019-486-959-952-072; 020-387-830-072-113; 021-409-127-882-764; 021-501-656-709-344; 022-049-888-664-69X; 022-660-231-334-537; 024-881-465-321-917; 025-204-638-190-344; 025-615-970-308-152; 026-116-050-435-087; 026-176-358-077-671; 026-402-329-414-774; 026-424-759-400-249; 026-809-150-271-720; 026-992-163-988-200; 027-276-832-054-00X; 027-764-538-485-813; 028-608-342-394-305; 028-947-673-283-251; 029-558-552-174-988; 029-721-800-393-846; 029-967-853-300-957; 030-243-451-878-424; 030-451-439-154-307; 030-653-426-758-166; 031-821-635-568-955; 031-895-207-842-462; 032-429-467-815-071; 032-436-411-330-652; 032-535-470-358-472; 032-611-140-102-53X; 034-148-547-675-808; 034-582-929-302-638; 034-638-767-076-702; 035-448-575-172-934; 036-414-342-483-230; 036-863-626-200-697; 037-066-176-376-832; 037-153-089-127-606; 037-451-516-135-455; 037-905-644-390-788; 038-519-057-928-783; 038-584-671-391-358; 038-947-235-351-472; 039-110-812-304-847; 041-441-603-253-690; 042-397-201-535-733; 042-712-478-150-972; 043-287-924-286-987; 043-455-818-412-759; 043-704-662-463-131; 044-045-542-722-290; 044-466-488-655-239; 044-485-103-503-562; 045-060-196-635-443; 045-147-082-642-76X; 045-230-861-572-569; 045-348-741-753-633; 045-581-768-016-132; 046-949-190-096-058; 047-134-478-431-993; 047-141-233-329-072; 047-748-493-540-289; 048-724-067-002-349; 049-190-395-957-497; 050-065-737-688-964; 050-220-727-983-705; 051-566-710-178-931; 051-647-739-244-271; 051-718-396-534-597; 051-729-760-078-879; 051-783-493-799-520; 051-871-860-911-220; 052-478-006-542-580; 052-547-519-377-337; 052-995-714-284-856; 053-042-585-140-875; 053-052-240-678-37X; 053-089-836-403-181; 053-295-060-350-429; 054-111-091-508-257; 054-286-317-445-661; 054-487-186-748-566; 054-615-225-782-34X; 054-650-646-723-325; 054-679-804-264-937; 054-746-521-444-660; 055-023-201-771-045; 056-639-513-703-828; 056-918-312-788-900; 057-163-396-901-969; 057-265-482-308-333; 057-383-494-742-484; 057-627-902-651-839; 058-283-975-147-051; 058-573-027-425-205; 058-912-748-761-659; 059-321-752-461-052; 059-606-042-130-979; 059-998-407-959-110; 060-264-087-669-087; 060-522-471-531-487; 060-927-912-870-042; 061-362-647-240-015; 061-720-677-620-075; 062-092-708-894-354; 062-839-054-285-789; 063-058-881-442-359; 065-004-635-470-265; 065-174-205-652-917; 065-420-968-243-565; 067-225-115-532-655; 068-009-904-033-20X; 069-694-907-220-953; 070-696-074-298-768; 071-155-676-270-783; 073-697-795-232-121; 074-353-036-294-302; 074-886-284-079-89X; 075-336-263-231-91X; 078-144-615-231-140; 078-799-026-640-031; 078-865-442-212-100; 079-084-480-746-394; 079-455-709-293-064; 081-731-293-320-582; 082-621-639-771-057; 082-925-425-202-855; 084-851-112-797-089; 084-870-217-233-881; 085-781-891-153-201; 085-926-379-146-867; 086-516-280-912-167; 087-412-592-223-424; 088-089-459-593-265; 088-403-640-674-978; 088-541-586-768-839; 088-665-040-847-10X; 089-960-573-144-018; 090-244-176-708-391; 092-042-700-461-864; 092-435-948-331-606; 092-805-309-937-084; 093-063-705-187-525; 093-602-945-005-305; 094-867-189-427-616; 095-202-863-696-798; 095-639-343-066-495; 095-830-862-439-164; 097-004-432-326-387; 097-348-597-402-463; 099-186-004-474-538; 099-912-388-390-424; 100-365-546-093-884; 100-559-203-366-591; 101-228-352-393-489; 101-336-081-417-474; 101-373-873-141-042; 101-428-787-142-677; 101-873-630-523-282; 102-667-505-094-481; 102-987-412-735-190; 103-237-120-250-97X; 103-449-746-636-051; 103-662-272-954-80X; 104-315-561-425-218; 104-327-934-058-595; 106-820-019-891-26X; 106-950-495-488-370; 107-487-651-435-436; 108-159-985-561-540; 108-325-522-821-191; 108-684-850-585-321; 108-697-694-515-040; 108-995-944-873-736; 109-299-872-389-685; 110-959-311-478-094; 111-072-555-941-400; 112-114-080-993-950; 112-676-394-312-403; 114-324-044-418-965; 114-838-116-445-507; 115-021-942-651-070; 115-367-631-932-674; 115-701-701-591-504; 115-797-377-224-241; 118-076-182-696-555; 121-286-095-966-16X; 121-409-535-909-300; 121-640-768-515-806; 121-957-892-681-284; 122-435-114-469-488; 122-685-447-439-596; 123-124-115-029-802; 123-396-916-678-764; 123-516-191-325-091; 124-355-806-631-020; 125-786-242-868-479; 127-105-841-730-873; 127-503-343-241-501; 129-017-180-009-589; 130-473-416-183-327; 132-782-436-069-259; 132-866-850-473-597; 134-814-456-240-339; 134-995-800-100-657; 135-196-690-679-527; 138-668-053-203-595; 140-525-862-533-707; 140-927-093-273-710; 141-422-265-606-511; 147-821-443-160-361; 149-336-209-935-468; 150-836-369-480-921; 154-201-379-823-568; 155-033-337-127-94X; 155-843-421-210-425; 155-935-712-636-598; 156-144-569-159-711; 156-859-233-595-287; 157-953-303-137-079; 159-466-191-389-70X; 163-972-980-299-850; 167-228-997-972-925; 170-989-166-868-03X; 171-505-052-558-650; 171-607-451-080-874; 175-577-265-946-823; 187-486-982-921-129; 187-565-202-934-646; 191-850-496-024-791; 195-915-844-732-699; 198-557-363-843-787,18,true,cc-by,hybrid -139-120-001-770-574,The global scenario of hydrogeochemical research on glacier meltwater: a bibliometric and visualization analysis.,2023-05-26,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Ramesh Kumar; Prity Singh Pippal; Rajesh Kumar; Pankaj Kumar; Atar Singh; Payal Sharma,"In recent years, there has been a rapid increase in scientific research into hydrogeochemical research on glacier meltwater. Nevertheless, systematic and quantitative analyses are lacking to investigate how this research field has developed over the years. As a result, this study is aimed at examining and evaluating recent research trends and frontiers in hydrogeochemical research on glacier meltwater throughout the previous 20 years (2002-2022) and at locating collaboration networks. This is the first global-scale study, and visualization of the key hotspots and trends in hydrogeochemical research has been presented here. The Web of Science Core Collection (WoSCC) database aided in the retrieval of research publications related to hydrogeochemical research of glacier meltwater published between 2002 and 2022. From the beginning of 2002 till July 2022, 6035 publications on the hydrogeochemical study of glacier meltwater were compiled. The result revealed that the number of published papers on the hydrogeochemical study of glacier meltwater at higher altitudes had grown exponentially, with USA and China being the main research countries. The number of publications produced from the USA and China accounts for about half (50%) of all publications from the top 10 countries. Kang SC, Schwikowski M, and Tranter M are highly influential authors in hydrogeochemical research of glacier meltwater. However, the research from developed nations, particularly the United States, emphasizes hydrogeochemical research more than those from developing countries. In addition, the research on glacier meltwater's role in streamflow components is limited, particularly in the high-altitude regions and needs to be enhanced.",30,30,74612,74627,Meltwater; Glacier; Physical geography; Geology; Geography,Bibliometric analysis; Biblioshiny; Hydro-geochemistry; VOSviewer; Web of Science Core Collection (WoSCC),"Ice Cover; Bibliometrics; China; Databases, Factual; Hydrolases",Hydrolases,,https://www.researchsquare.com/article/rs-2335935/latest.pdf https://doi.org/10.21203/rs.3.rs-2335935/v1,http://dx.doi.org/10.1007/s11356-023-27642-6,37231134,10.1007/s11356-023-27642-6,,,0,001-210-626-936-647; 001-686-075-927-587; 002-112-652-843-29X; 002-209-285-575-393; 003-354-785-635-716; 005-804-798-176-094; 006-953-368-808-51X; 009-538-958-230-456; 012-317-313-776-290; 012-595-896-731-683; 012-973-958-795-486; 013-507-404-965-47X; 013-524-854-219-241; 016-111-600-017-213; 017-208-493-700-814; 018-378-616-737-261; 022-098-059-233-05X; 022-764-355-432-75X; 026-383-515-630-824; 030-036-347-223-194; 033-684-001-828-473; 035-019-224-014-496; 036-315-537-462-487; 041-163-314-001-123; 041-910-360-555-238; 042-735-877-389-210; 048-241-207-307-130; 048-478-934-614-984; 049-303-089-841-806; 049-892-649-775-498; 050-437-349-950-611; 051-952-809-481-338; 052-427-396-761-85X; 054-304-243-023-736; 056-387-741-244-346; 057-336-234-498-479; 057-803-697-074-453; 058-531-269-515-136; 061-786-393-143-969; 063-536-014-796-558; 064-400-499-357-900; 065-505-248-488-428; 066-130-997-335-291; 067-445-612-400-076; 069-006-088-467-503; 069-290-716-511-087; 070-545-073-050-172; 075-632-957-177-037; 078-820-231-272-729; 080-003-597-371-686; 088-463-435-679-803; 089-120-159-003-656; 092-294-066-749-369; 093-218-840-885-661; 093-861-676-843-015; 099-194-149-847-876; 099-898-258-021-227; 101-119-277-246-100; 103-560-046-694-192; 107-065-903-278-298; 113-969-849-068-01X; 120-974-286-046-262; 121-364-320-221-756; 124-814-014-669-995; 125-151-201-724-664; 126-891-704-162-958; 135-735-289-147-84X; 143-438-064-948-709; 146-340-710-814-806; 172-008-782-082-411; 175-309-876-890-67X; 186-946-067-346-245; 193-810-632-949-745; 198-870-332-094-067,12,true,,green -139-207-154-065-931,Financial Analytics and Decision-Making Strategies: Future Prospects from Bibliometrix Based on R Package,2023-08-15,2023,book chapter,Lecture Notes in Operations Research,2731040x; 27310418,Springer International Publishing,,Konstantina Ragazou; Ioannis Passas; Alexandros Garefalakis; Constantin Zopounidis,,,,159,173,Analytics; Leverage (statistics); Business intelligence; Data science; Business analytics; Data analysis; Computer science; Software analytics; Process (computing); Finance; Software; Knowledge management; Data mining; Business; Software development; Business analysis; Business model; Marketing; Software development process; Artificial intelligence; Programming language; Operating system,,,,,,http://dx.doi.org/10.1007/978-3-031-29050-3_9,,10.1007/978-3-031-29050-3_9,,,0,003-258-996-320-140; 004-860-464-535-771; 006-591-040-577-644; 014-927-226-607-422; 016-057-317-993-302; 030-062-121-786-225; 036-420-155-497-62X; 044-983-545-193-612; 051-593-063-031-071; 059-369-132-699-716; 059-420-594-272-558; 059-980-551-202-109; 064-575-263-905-098; 068-146-936-698-979; 084-683-950-535-31X; 085-488-007-927-147; 097-913-528-835-985; 101-876-628-533-063; 109-123-621-448-733; 128-312-293-398-424; 128-576-536-604-472; 131-072-733-489-695; 135-510-384-287-704; 149-503-269-804-078; 150-760-047-559-292; 160-345-596-234-962; 172-945-549-210-401,1,false,, -139-727-203-078-819,Bibliometric analysis and visualization of research trends in radiation dermatitis in the past twenty years.,2025-04-15,2025,journal article,"Radiation oncology (London, England)",1748717x,Springer Science and Business Media LLC,United Kingdom,Xinyi Zhang; Yuai Xiao; Ang Li; Yuchong Wang; Jianguo Xu; Kexin Chen; Haoyuan Zheng; Minliang Wu; Chunyu Xue,"This study aims to explore the most influential countries/regions, institutions, journals, authors, keywords, and trends in the study of the mechanism and treatments of radiation dermatitis (RD) from 2003 to 2023 using bibliometric analysis.; The literature associated with RD was retrieved from the Web of Science Core Collection, only articles and reviews in English were included. Individual articles were reviewed to identify the authorship, published journal, journal impact factor, institution and country of origin, and year of publication.; A total of 6,453 authors from 1,605 institutions in 64 countries/regions published 1,062 RD-related literature. The United States was the most productive country. The Unicancer in France was the institution that published the majority of articles on RD. Edward Chow was the most productive author and Supportive Care in Cancer contributed the most articles. Advanced head and neck cancer is the most common cause of RD. The mechanism research mainly focused on nitric oxide, oxidative stress, and apoptosis in recent years, and Mepitel film, Mepilex Lite, and PBMT were the main preventive and therapeutic measures for RD.; Our bibliometric studies provide a thorough overview of RD and valuable insights and ideas for scholars in this discipline.; © 2025. The Author(s).",20,1,54,,Medicine; Visualization; MEDLINE; Medical physics; Dermatology; Data mining; Computer science; Political science; Law,Bibliometrics; Radiation dermatitis; Randomized controlled trial; Research trend,Humans; Bibliometrics; Biomedical Research/trends; Journal Impact Factor; Radiodermatitis/etiology,,,,http://dx.doi.org/10.1186/s13014-025-02629-4,40234910,10.1186/s13014-025-02629-4,,PMC12001518,0,000-376-360-312-91X; 001-537-160-577-80X; 005-743-831-014-235; 007-500-155-247-91X; 009-093-475-807-063; 009-872-885-203-898; 013-626-078-396-604; 014-570-009-870-372; 017-571-539-498-882; 019-023-819-931-236; 019-706-336-089-489; 021-093-579-062-46X; 027-072-063-937-136; 028-420-619-474-013; 034-573-137-534-815; 038-037-887-163-482; 050-058-679-888-347; 075-685-387-244-101; 079-281-066-408-667; 093-080-461-244-216; 094-159-592-916-885; 094-766-749-373-722; 099-151-963-518-647; 100-518-910-563-059; 108-984-023-541-055; 114-265-562-046-72X; 129-805-446-405-413; 131-595-290-491-042; 154-822-599-269-468; 156-966-232-618-823; 162-241-514-030-373,0,true,"CC BY, CC0",gold -140-159-221-012-111,Bibliometric analysis of artificial intelligence cyberattack detection models,2025-03-21,2025,journal article,Artificial Intelligence Review,15737462; 02692821,Springer Science and Business Media LLC,Netherlands,Blessing Guembe; Sanjay Misra; Ambrose Azeta; Ines Lopez-Baldominos,"Abstract; Cybercriminals have increasingly adopted advanced and cutting-edge methods that expand the scale and speed of their attacks in recent years. This trend coincides with the rising demand for and scarcity of highly skilled cybersecurity specialists, making them both expensive and difficult to find. Recently, researchers have demonstrated the effectiveness of Artificial Intelligence (AI) approaches in combating sophisticated cyberattacks. However, comprehensive bibliometric data illustrating the study of AI approaches in cyberattack detection remain sparse. This study addresses this gap by investigating the current state of AI-based cyberattack detection research. The study analyzed the Scopus database using bibliometric analysis on a pool of over 2,338 articles published between 2014 and 2024, including 1217 journal articles, 828 conference papers, 121 conference reviews, 85 book chapters, 70 reviews, 5 editorials, and 2 books and short surveys. The study explores various AI-based cyberattack detection approaches globally, focusing on machine learning and deep learning algorithms. The bibliometric analysis was conducted using R, an open-source statistical tool, and Biblioshiny. The findings establish that AI, particularly machine learning and deep learning, enhances intrusion detection accuracy and is a growing research trend. Researchers have effectively employed these techniques for malware detection. The USA leads in AI cyberattack research, followed by India, China, Saudi Arabia, and Australia. Despite publishing fewer articles, Canada and Italy received significant citations. Additionally, strong research collaboration exists among the USA, China, Australia, Saudi Arabia, and India. Keyword analysis highlights AI’s effectiveness in identifying patterns and malicious behaviours, enhancing intrusion detection even in complex cyberattacks. Machine learning can detect intrusions based on anomalies caused by malicious or compromised devices, as well as unknown threats, with speed, accuracy, and a low false-positive rate.",58,6,,,Computer science; Artificial intelligence,,,,Institute for Energy Technology,https://link.springer.com/content/pdf/10.1007/s10462-025-11167-0.pdf https://doi.org/10.1007/s10462-025-11167-0,http://dx.doi.org/10.1007/s10462-025-11167-0,,10.1007/s10462-025-11167-0,,,0,000-134-697-698-297; 001-030-262-780-945; 008-650-674-764-863; 009-702-508-682-684; 011-930-332-562-246; 012-158-458-605-331; 013-507-404-965-47X; 014-563-199-723-035; 018-415-495-846-604; 020-154-411-382-793; 023-793-512-470-792; 025-949-534-940-91X; 028-811-996-820-813; 029-836-844-003-168; 030-818-862-666-068; 031-126-823-255-791; 034-446-688-560-241; 034-519-495-322-081; 035-214-296-603-090; 039-344-430-031-013; 051-276-546-511-935; 053-154-199-670-460; 054-918-470-724-66X; 056-092-324-854-911; 059-507-729-500-979; 059-509-458-757-762; 061-001-263-061-612; 064-589-935-699-918; 064-611-733-820-247; 064-615-158-502-303; 073-684-946-590-856; 078-677-783-915-076; 081-124-526-320-07X; 085-809-914-621-496; 086-457-959-114-885; 086-789-551-374-991; 088-097-202-235-825; 095-632-126-282-237; 098-019-137-466-537; 102-365-000-626-872; 113-958-147-920-761; 117-930-534-170-244; 119-397-967-338-890; 131-137-391-147-71X; 136-010-897-411-913; 141-484-558-782-483; 145-848-958-231-138; 146-088-894-408-260; 156-192-460-295-839; 170-046-698-474-679; 176-710-332-790-600; 184-019-073-964-250; 187-327-468-217-042; 189-218-852-537-163; 194-190-744-865-230; 195-114-750-220-772,0,true,cc-by,hybrid -140-163-504-743-768,State-of-the-Art Status of Google Earth Engine (GEE) Application in Land and Water Resource Management: A Scientometric Analysis,2025-02-26,2025,journal article,Journal of Geovisualization and Spatial Analysis,25098810; 25098829,Springer Science and Business Media LLC,,Nishtha Sharnagat; Anupam Kumar Nema; Prabhash Kumar Mishra; Nitesh Patidar; Rahul Kumar; Ashwini Suryawanshi; Lakey Radha,,9,1,,,Gee; Resource (disambiguation); State (computer science); Earth (classical element); Environmental resource management; Environmental science; Geography; Meteorology; Computer science; Generalized estimating equation; Mathematics; Computer network; Algorithm; Machine learning; Mathematical physics,,,,,,http://dx.doi.org/10.1007/s41651-025-00218-3,,10.1007/s41651-025-00218-3,,,0,000-861-409-841-37X; 001-066-527-787-013; 001-907-368-085-121; 002-052-422-936-00X; 002-428-087-460-392; 002-611-443-692-065; 002-988-054-904-511; 003-139-204-418-608; 003-192-969-136-808; 003-298-361-050-139; 003-832-032-240-73X; 003-910-429-337-143; 004-481-969-741-693; 005-280-849-445-262; 005-297-948-369-235; 005-507-129-283-190; 006-152-710-252-028; 006-827-764-988-762; 007-254-134-869-866; 007-383-337-108-291; 007-930-580-244-55X; 008-076-515-405-51X; 008-454-535-180-587; 008-925-507-603-317; 011-537-956-606-349; 012-804-831-619-306; 013-507-404-965-47X; 013-691-761-891-934; 014-630-412-469-820; 015-595-956-910-149; 015-721-678-939-316; 016-767-128-613-442; 019-298-265-172-436; 019-529-867-614-030; 020-529-409-245-78X; 020-780-609-631-626; 021-379-500-733-552; 024-644-200-390-344; 026-626-418-188-302; 028-074-507-947-948; 028-436-026-220-41X; 028-724-802-425-642; 029-012-096-338-146; 031-235-869-073-638; 032-099-783-077-876; 033-293-368-004-341; 035-786-415-321-322; 036-954-347-747-757; 037-506-002-876-69X; 037-574-543-664-766; 038-174-088-547-608; 039-197-507-476-313; 040-782-646-876-723; 044-218-957-649-681; 044-544-900-047-245; 045-522-899-001-90X; 045-816-169-574-283; 046-992-864-415-70X; 047-049-448-119-644; 047-723-583-662-828; 048-538-377-746-379; 049-181-846-789-468; 049-497-237-570-314; 049-603-334-301-497; 050-074-586-638-074; 050-766-855-776-561; 051-121-477-223-879; 051-276-808-733-715; 051-497-912-608-294; 053-111-474-407-596; 054-752-515-196-69X; 058-572-302-082-215; 059-077-775-225-501; 060-379-822-979-859; 061-311-904-195-092; 061-678-576-386-199; 061-939-316-014-113; 062-115-913-054-716; 063-252-929-707-950; 064-699-380-514-066; 064-788-617-788-191; 065-450-041-881-825; 065-464-532-297-348; 066-148-237-951-484; 066-266-212-193-231; 066-730-421-213-995; 069-384-592-939-897; 069-632-253-490-052; 071-877-079-998-738; 072-511-757-232-783; 073-116-102-560-969; 073-616-054-509-325; 073-896-981-020-431; 074-489-630-749-149; 075-174-769-548-835; 075-542-952-823-096; 078-559-377-490-853; 079-278-479-639-749; 079-319-627-537-487; 081-523-568-781-26X; 081-717-013-086-20X; 084-051-393-993-08X; 085-141-628-475-339; 085-163-053-279-536; 085-604-832-796-381; 086-316-104-322-778; 086-527-708-841-691; 087-012-570-895-841; 087-493-437-873-774; 088-138-121-192-657; 089-346-699-555-226; 089-901-866-638-10X; 092-261-977-253-865; 092-926-173-654-165; 093-189-113-552-510; 093-421-521-708-047; 093-692-438-358-255; 094-325-455-799-935; 095-527-668-674-927; 097-155-350-711-976; 097-283-382-181-742; 097-344-913-944-910; 101-652-363-854-917; 101-822-213-417-120; 102-474-700-817-517; 105-320-393-145-614; 105-519-093-197-330; 106-002-693-753-403; 106-647-796-404-458; 107-304-592-420-044; 109-271-396-864-507; 109-618-345-928-814; 110-265-023-949-932; 110-545-645-813-710; 111-512-742-226-636; 113-155-126-789-312; 113-275-629-517-358; 115-559-177-530-267; 115-939-107-956-849; 117-285-608-330-476; 122-579-687-839-282; 123-541-524-607-05X; 126-183-376-102-819; 126-257-629-889-939; 126-389-849-727-952; 126-865-418-694-831; 127-563-510-078-866; 127-880-136-883-505; 128-220-089-098-020; 128-422-962-711-316; 129-894-226-770-854; 135-369-712-576-098; 138-581-168-508-880; 138-899-713-904-003; 140-798-944-722-10X; 141-444-216-453-210; 142-015-223-481-544; 143-994-241-368-068; 144-680-911-817-155; 145-706-013-895-679; 147-537-273-266-260; 148-905-746-259-291; 150-177-729-757-933; 152-196-239-187-321; 154-939-519-729-081; 155-431-124-410-382; 156-620-126-803-058; 165-320-271-209-575; 168-608-545-323-829; 171-422-984-831-81X; 172-293-100-901-914; 172-821-066-911-030; 173-627-983-922-885; 175-350-995-742-690; 175-655-044-626-800; 177-686-508-572-383; 178-583-775-162-316; 179-219-500-339-472; 182-134-561-716-628; 185-064-654-260-023; 186-204-438-645-293; 186-253-284-474-153; 187-214-580-427-743; 190-981-442-605-666; 191-331-071-163-900; 194-560-278-789-300; 194-830-970-241-437; 196-362-128-319-632; 196-476-057-605-708; 197-937-083-182-003; 198-398-567-478-093; 198-859-249-484-956; 199-633-185-633-565,0,false,, -140-301-258-010-317,Prefabricated Construction Risks: A Holistic Exploration through Advanced Bibliometric Tool and Content Analysis,2023-08-02,2023,journal article,Sustainability,20711050,MDPI AG,Switzerland,Merve Anaç; Gulden Gumusburun Ayalp; Kamil Erdayandi,"Prefabricated construction (PC) offers advantages to the architecture, engineering, and construction (AEC) industry such as quality production, fast project completion, low waste output, high environmental sensitivity, and high security. Although PC has several advantages, knowledge gaps persist, necessitating a comprehensive bibliometric study. This research adopts a holistic bibliometric approach, combining qualitative (systematic literature review) and quantitative (bibliometric analysis) methods to assess the current state of prefabricated construction risks (PCRs) research and identify the literature trends. Unlike previous PCRs studies, our research capitalizes on the quantitative analysis capabilities of the Bibliometrix R-tool. We introduce innovative measures, such as the h-index, thematic mapping, and trend topic analysis, to deepen the understanding of the PCRs research landscape. Moreover, this study explores the intellectual structure of PCR research through keyword analysis, cluster analysis, and thematic evaluation, providing valuable insights into scientific studies, collaborations, and knowledge dissemination. In our study, following a systematic literature review to understand the existing knowledge, the R-studio Bibliometrix package is used to map the field, identify gaps in the field, and analyze the trends. This study involves a comprehensive bibliometric analysis of 150 articles in the field of PCRs, with data obtained from the Web of Science spanning from 2000 to 2023. The findings from the analyses reveal that the studies were divided into four different clusters: management, programming, logistics, and supply chain. Additionally, themes such as the integration of PC with Building Information Management (BIM), barriers, and stakeholders were also explored. The analyses indicate a growing awareness of PCRs, particularly in specific areas such as management, performance, and supply chain. This study stands out for its unique methods, analytical approach, and the use of specialized software. It provides valuable insights and suggestions for future studies.",15,15,11916,11916,Thematic analysis; Content analysis; Field (mathematics); Computer science; Systematic review; Knowledge management; Data science; Quantitative analysis (chemistry); Thematic map; Qualitative research; Sociology; Geography; Social science; Chemistry; Mathematics; Cartography; MEDLINE; Chromatography; Political science; Pure mathematics; Law,,,,"Ministry of National Education, Republic of Turkey",https://www.mdpi.com/2071-1050/15/15/11916/pdf?version=1691026497 https://doi.org/10.3390/su151511916,http://dx.doi.org/10.3390/su151511916,,10.3390/su151511916,,,0,000-632-377-268-396; 001-699-876-325-52X; 004-548-659-081-582; 004-600-588-256-79X; 006-616-101-667-538; 009-930-546-394-717; 009-966-323-010-477; 013-507-404-965-47X; 013-524-854-219-241; 014-277-268-553-715; 015-000-423-954-565; 015-132-865-093-621; 018-067-060-066-520; 018-888-382-589-242; 020-524-876-495-742; 020-850-050-317-636; 021-666-914-768-044; 022-534-474-138-197; 024-394-161-476-639; 024-899-450-837-000; 025-237-960-951-114; 027-049-241-972-191; 027-300-187-489-349; 027-827-764-455-79X; 028-549-276-089-849; 031-947-697-103-401; 034-008-303-942-127; 035-264-311-077-750; 036-611-279-769-465; 037-332-040-500-266; 037-460-244-639-493; 044-094-949-172-746; 044-580-997-960-097; 046-793-612-528-597; 048-641-076-740-323; 052-288-521-041-812; 053-287-815-023-806; 054-660-014-355-017; 056-048-934-730-74X; 061-167-142-696-232; 066-017-624-730-868; 066-338-096-354-826; 070-420-576-682-498; 071-877-629-674-595; 072-286-378-931-05X; 075-086-285-773-550; 075-247-942-252-54X; 077-975-056-090-185; 078-497-361-442-151; 079-557-924-964-198; 079-830-732-837-041; 080-495-122-614-203; 081-547-256-855-879; 082-723-047-193-406; 083-118-993-595-269; 084-121-333-560-435; 086-052-858-208-094; 089-607-531-687-447; 089-703-512-998-338; 091-665-339-643-898; 095-300-218-473-734; 095-662-850-723-280; 100-261-773-000-039; 101-472-342-663-101; 102-694-788-795-301; 103-076-145-435-992; 104-919-753-218-202; 108-033-960-943-565; 108-959-130-838-714; 112-141-311-860-957; 112-807-944-006-919; 114-887-377-326-507; 116-858-095-731-520; 117-438-718-546-213; 120-801-966-303-458; 121-652-742-486-910; 121-766-142-846-172; 125-429-378-769-714; 127-064-853-069-498; 128-860-810-859-565; 130-708-391-881-033; 130-855-640-928-171; 132-348-029-682-716; 136-336-408-086-276; 136-941-571-313-614; 138-627-544-815-448; 138-701-076-577-639; 141-210-123-848-625; 141-487-455-562-035; 149-385-776-417-916; 153-845-370-247-864; 156-003-591-016-419; 156-635-462-535-963; 158-137-578-656-290; 159-681-349-256-109; 168-854-920-289-428; 171-616-005-488-225; 178-317-795-881-412; 178-544-880-318-368; 185-706-357-968-30X; 190-728-834-015-797; 195-384-110-649-028,17,true,,gold -140-340-673-258-725,Escaneo científico sobre tendencias en Agricultura Campesina Familiar Étnica y Comunitaria,,2024,report,,,Corporación colombiana de investigación agropecuaria - AGROSAVIA,,ALEXIS MORALES CASTAÑEDA,"La Agricultura Campesina Familiar Étnica y Comunitaria (ACFEC) representa una estrategia fundamental para la seguridad alimentaria, la sostenibilidad ambiental y la cohesión social, especialmente ante desafíos como el cambio climático y la pérdida de agrobiodiversidad. Este estudio identifica tendencias de investigación sobre ACFEC mediante vigilancia tecnológica y análisis cienciométrico de publicaciones en Scopus® entre 2020 y 2024. Utilizando herramientas como Bibliometrix® y VOSviewer®, se generaron mapas temáticos y clústeres que permiten visualizar tópicos clave y relaciones entre ellos, aportando insumos estratégicos para fortalecer sistemas agroalimentarios más resilientes e inclusivos",,,,,Political science; Geography,,,,,,http://dx.doi.org/10.21930/agrosavia.escaneocientifico.2024.2,,10.21930/agrosavia.escaneocientifico.2024.2,,,0,,0,false,, -140-341-473-218-045,Vibration Energy Harvesting: A Bibliometric Analysis of Research Trends and Challenges,2024-10-13,2024,journal article,Journal of Vibration Engineering & Technologies,25233920; 25233939,Springer Science and Business Media LLC,,Helal Al-Quaishi; Caijiang Lu; W. K. Alani,,12,S2,2253,2281,Bibliometrics; Energy (signal processing); Environmental science; Regional science; Data science; Geography; Computer science; Library science; Statistics; Mathematics,,,,,,http://dx.doi.org/10.1007/s42417-024-01533-7,,10.1007/s42417-024-01533-7,,,0,001-249-990-863-059; 002-380-726-759-80X; 003-482-763-995-047; 003-574-755-455-655; 004-340-394-844-093; 005-846-175-372-06X; 006-655-565-154-871; 007-092-897-948-440; 009-721-259-613-736; 010-391-088-877-433; 011-170-137-136-269; 011-615-819-409-454; 011-706-832-799-438; 012-948-078-620-19X; 013-449-942-452-345; 015-894-238-037-736; 017-190-724-780-047; 024-947-868-984-52X; 025-077-563-895-411; 026-326-542-297-798; 028-034-251-694-580; 033-332-634-406-650; 033-586-560-392-566; 037-710-025-623-925; 039-946-076-321-365; 041-340-407-556-093; 042-755-259-129-09X; 044-551-414-706-327; 044-711-886-326-189; 052-923-819-429-262; 053-657-038-341-353; 054-678-041-786-600; 055-113-788-840-239; 056-901-449-896-717; 058-787-539-628-261; 060-896-741-226-631; 062-991-190-741-642; 063-254-627-463-283; 064-441-749-227-158; 065-307-448-849-868; 066-045-693-076-01X; 067-544-340-503-007; 069-500-307-257-658; 070-116-258-344-171; 072-023-567-393-954; 072-161-097-440-669; 075-104-545-307-705; 075-482-715-913-010; 075-542-113-655-263; 077-980-931-638-150; 079-679-789-158-219; 080-692-457-524-632; 080-735-974-338-157; 081-278-797-000-66X; 083-650-360-724-332; 085-278-784-748-084; 090-716-416-134-132; 093-392-462-548-492; 095-659-354-672-202; 095-706-199-549-114; 099-039-700-745-864; 101-903-424-985-800; 104-163-858-244-530; 105-770-695-585-859; 107-758-603-324-100; 109-210-798-332-133; 111-101-929-826-504; 113-862-985-408-20X; 119-662-347-073-830; 122-520-166-933-306; 125-360-027-502-150; 126-257-629-889-939; 128-253-028-212-927; 135-345-335-445-394; 137-721-851-930-264; 140-728-499-721-219; 143-923-929-307-37X; 144-986-542-438-230; 146-000-485-485-776; 146-595-626-559-341; 147-221-396-156-255; 148-913-368-367-964; 151-507-712-541-808; 154-535-414-802-675; 158-393-194-306-104; 158-448-955-678-961; 165-377-151-374-215; 168-452-274-010-629; 180-523-746-755-152; 181-840-614-881-371; 184-408-423-645-25X; 185-194-519-242-602; 194-592-561-917-079; 197-500-481-794-732; 198-054-264-168-558; 198-169-984-377-817,1,false,, -141-040-229-949-142,A systematic review with bibliometric analysis of different approaches and methodologies for undertaking flood vulnerability research,2023-06-16,2023,journal article,Sustainable Water Resources Management,23635037; 23635045,Springer Science and Business Media LLC,,Thuy Linh Nguyen; Chisato Asahi; Thi An Tran,,9,4,,,Flood myth; Vulnerability assessment; Vulnerability (computing); Scopus; Natural hazard; Hazard; Environmental resource management; Computer science; Geography; Environmental science; Political science; Psychological intervention; Psychology; MEDLINE; Chemistry; Computer security; Archaeology; Organic chemistry; Psychiatry; Meteorology; Law,,,,,,http://dx.doi.org/10.1007/s40899-023-00865-8,,10.1007/s40899-023-00865-8,,,0,000-975-778-494-604; 001-341-301-710-228; 001-446-467-925-991; 002-129-763-550-132; 002-432-707-078-939; 002-808-980-807-963; 003-474-663-104-913; 007-819-616-862-224; 008-137-474-744-684; 008-311-235-014-407; 009-223-469-817-428; 010-150-819-103-291; 010-707-172-063-764; 011-323-609-113-335; 012-764-960-431-488; 013-507-404-965-47X; 014-289-667-106-865; 014-758-890-264-320; 014-948-348-521-46X; 015-394-707-541-142; 015-482-607-406-277; 015-698-863-823-03X; 016-089-323-217-269; 016-282-322-882-587; 017-750-600-412-958; 018-438-833-717-314; 019-172-644-267-239; 019-455-085-625-422; 021-263-062-124-540; 021-266-685-292-528; 021-458-162-382-379; 023-567-751-264-595; 023-872-814-849-488; 025-632-652-825-183; 027-098-877-495-934; 027-741-797-232-78X; 028-696-288-444-764; 029-203-842-447-160; 029-904-866-650-114; 030-890-476-345-190; 031-033-052-622-385; 031-136-061-230-377; 033-294-618-977-619; 034-496-041-948-769; 034-661-678-717-606; 034-737-063-153-89X; 035-229-808-948-431; 035-467-164-739-602; 037-963-810-023-584; 038-056-452-896-357; 038-602-359-467-692; 042-190-595-922-948; 042-328-634-464-150; 043-571-599-279-297; 046-423-548-163-15X; 046-824-653-021-61X; 046-939-639-907-043; 048-089-565-548-977; 048-406-344-462-009; 048-519-986-158-704; 049-640-514-570-136; 050-899-307-852-147; 050-935-828-517-411; 051-308-290-298-061; 051-647-739-244-271; 054-818-565-070-154; 056-974-458-083-985; 057-076-670-944-086; 059-139-416-364-295; 060-130-892-689-490; 061-817-645-572-110; 062-669-493-517-861; 065-900-628-294-473; 066-920-908-410-058; 067-254-735-156-710; 068-324-144-003-744; 069-125-461-805-649; 069-478-193-763-57X; 071-305-477-543-241; 073-103-031-659-685; 076-422-622-541-301; 076-827-003-933-598; 082-792-736-923-469; 083-233-429-885-517; 086-256-781-980-645; 090-018-819-818-135; 090-472-187-876-600; 090-592-593-540-64X; 090-713-658-569-91X; 091-235-851-670-510; 091-536-403-374-303; 092-039-371-755-337; 097-712-647-457-197; 101-633-439-044-512; 102-184-456-671-599; 106-839-409-427-219; 107-806-988-668-521; 107-896-693-157-873; 107-901-044-108-311; 108-121-557-014-205; 111-218-105-732-379; 113-275-843-506-713; 115-492-966-243-638; 117-408-418-849-098; 120-921-052-381-501; 122-884-061-889-190; 125-440-550-423-422; 125-466-652-240-796; 125-713-006-886-82X; 127-655-403-797-492; 128-567-396-845-033; 131-595-526-754-604; 135-697-131-813-553; 136-138-420-052-75X; 136-841-026-961-28X; 141-188-269-200-321; 143-498-359-377-725; 150-177-830-493-362; 154-156-035-104-068; 159-744-522-099-326; 162-606-827-635-460; 171-887-539-048-990; 181-800-418-474-289; 188-426-880-053-342; 189-576-960-248-633; 198-494-361-623-857,3,false,, -141-047-336-170-179,Emerging trends in GIS application on cultural heritage conservation: a review,2024-05-06,2024,journal article,Heritage Science,20507445,Springer Science and Business Media LLC,United States,Beibei Liu; Cong Wu; Weixing Xu; Yingning Shen; Fengliang Tang,"Abstract; Geographic Information Systems (GIS)-based technologies are increasingly crucial in the domain of cultural heritage conservation, facilitating the construction of dynamic information management systems and serving as robust platforms for research and display. This review utilizes CiteSpace and Bibliometrix R language to perform a bibliometric analysis of academic literature sourced from the Web of Science (WoS) Core Collection, focusing on the application of GIS in cultural heritage conservation. The analysis covers a broad spectrum of academic articles, identifying research hotspots, patterns of national cooperation, interdisciplinary mobility, knowledge structure, and developmental trends. The findings reveal that this research area is experiencing a phase of steady growth. While three emerging trends have been identified, demonstrating significant theoretical and technical advancements, there remains considerable potential for enhancing in their practical implication within conservation efforts. The study advocates for the integration of digital technologies into the humanities, emphasizing the need for a heritage database equipped with standardized data exchange protocols to support display and analytical functions. This systematic research approach not only illuminates new strategies for the inheritance and innovation in the conservation of cultural heritage, but also paves the way for future explorations in this increasingly vital field.",12,1,,,Cultural heritage; Data science; Field (mathematics); Knowledge management; Computer science; Geography; Archaeology; Mathematics; Pure mathematics,,,,Innovative Research Group Project of the National Natural Science Foundation of China,https://heritagesciencejournal.springeropen.com/counter/pdf/10.1186/s40494-024-01265-7 https://doi.org/10.1186/s40494-024-01265-7,http://dx.doi.org/10.1186/s40494-024-01265-7,,10.1186/s40494-024-01265-7,,,0,002-358-443-949-32X; 002-698-928-532-427; 002-818-752-829-393; 004-689-099-057-363; 006-594-859-260-163; 007-573-344-067-691; 011-555-953-071-157; 013-507-404-965-47X; 017-259-732-002-387; 019-414-144-000-596; 021-139-222-103-231; 022-686-905-114-991; 023-853-949-563-993; 023-962-461-893-393; 025-225-016-659-26X; 026-982-329-698-854; 027-983-477-173-866; 029-732-182-178-770; 032-905-561-642-941; 034-527-375-835-907; 036-656-168-693-890; 043-329-624-329-300; 043-941-724-908-466; 048-592-753-181-234; 049-610-986-064-138; 049-794-515-360-933; 051-331-622-732-246; 052-912-314-553-66X; 057-179-810-869-711; 058-352-220-170-444; 058-373-435-769-289; 059-726-831-904-988; 061-877-295-914-153; 065-505-248-488-428; 066-035-899-048-349; 066-326-834-121-461; 071-369-910-650-455; 071-439-136-719-601; 080-009-461-385-242; 092-882-685-906-678; 098-228-055-047-970; 103-412-879-881-73X; 121-115-506-401-491; 130-049-395-961-712; 134-271-269-382-78X; 142-701-225-454-734; 147-665-314-367-161; 148-415-614-910-757; 154-216-809-180-745; 158-537-545-166-343; 159-899-846-440-443; 165-176-386-654-19X; 174-127-753-817-188; 179-853-959-254-892; 192-047-562-107-469,16,true,"CC BY, CC0",gold -141-141-866-638-526,Exploring the ESG reporting: A Bibliometric Literature Review and Future Research Agenda,2024-12-03,2024,preprint,,,MDPI AG,,Hicham Chbihi Kaddouri; Mohamed Kadous,"ESG reporting has attracted a lot of attention during the past several decades. However, bibliometric analysis on this topic remains limited. This paper aims to advance our understanding of ESG reporting, to cluster and map academic literature connected with ESG reporting and to attempt to give a research agenda for future research. We undertake a bibliometric analysis review of the current literature to discover present and future research directions of ESG reporting. In this study, the authors used datasets from the Web of Science (WoS) database, covering 869 research papers from 2014 to 2024 and using the Bibliometrix package also known as &ldquo;Bibliometrix 3.0&rdquo; or &ldquo;Biblioshiny&rdquo;. Bibliometric analysis offers a comprehensive overview of a certain field, such as authorship trends, geographical spread, research importance, influential authors and publications, new concepts, and emerging ideas. This research has implications for both scientific researchers and corporate world.",,,,,Political science; Bibliometrics; Data science; Regional science; Accounting; Business; Library science; Computer science; Sociology,,,,,,http://dx.doi.org/10.20944/preprints202412.0151.v1,,10.20944/preprints202412.0151.v1,,,0,,0,true,,bronze -141-302-242-630-109,"Structured review using TCCM and bibliometric analysis of international cause-related marketing, social marketing, and innovation of the firm",2019-10-21,2019,journal article,International Review on Public and Nonprofit Marketing,18651984; 18651992,Springer Science and Business Media LLC,Germany,Shiwangi Singh; Sanjay Dhir,,16,2,335,347,Marketing; Political science; Systematic review; Social marketing; Context (language use); Field (Bourdieu); Bibliometric analysis; Scopus,,,,,https://ideas.repec.org/a/spr/irpnmk/v16y2019i2d10.1007_s12208-019-00233-3.html https://dialnet.unirioja.es/servlet/articulo?codigo=7140251 https://link.springer.com/article/10.1007/s12208-019-00233-3,http://dx.doi.org/10.1007/s12208-019-00233-3,,10.1007/s12208-019-00233-3,2982203137,,0,002-052-422-936-00X; 003-020-961-124-641; 003-350-233-511-987; 005-628-669-515-774; 005-654-802-421-486; 005-760-425-630-600; 007-898-350-109-582; 008-087-599-839-764; 010-571-926-972-21X; 011-788-053-624-059; 013-435-411-344-76X; 013-507-404-965-47X; 013-668-507-320-962; 015-650-265-670-448; 016-472-956-101-620; 017-039-401-791-76X; 019-697-380-222-302; 019-738-048-708-739; 020-131-266-549-769; 024-562-682-457-361; 025-425-967-814-41X; 026-824-027-871-400; 027-716-768-108-304; 028-513-151-138-964; 030-162-942-660-767; 030-817-638-813-727; 030-867-927-747-469; 032-156-853-579-221; 032-226-726-401-253; 032-734-948-672-949; 035-143-661-867-268; 042-198-912-760-329; 043-510-773-801-10X; 043-961-062-352-742; 044-701-169-881-666; 045-549-857-532-091; 055-667-219-958-215; 056-126-178-605-45X; 058-685-322-221-594; 060-851-094-193-896; 061-775-653-155-701; 065-029-993-733-345; 065-789-206-347-368; 066-225-786-404-076; 066-858-470-188-282; 069-324-149-183-285; 069-348-969-268-571; 070-734-281-435-66X; 072-243-271-542-871; 072-379-563-340-406; 072-896-130-914-377; 079-565-233-262-541; 080-703-586-964-053; 081-873-862-047-568; 086-159-133-180-944; 086-881-079-233-635; 090-912-474-002-363; 097-336-677-089-771; 097-512-968-316-225; 100-224-961-210-452; 100-679-704-265-517; 103-920-581-159-278; 104-160-554-864-235; 104-574-479-341-978; 106-831-281-915-70X; 113-274-434-040-997; 117-404-452-177-864; 118-563-740-453-805; 119-688-663-276-918; 120-075-023-585-185; 120-855-433-716-683; 128-565-371-387-401; 130-002-825-739-874; 137-668-743-339-709; 146-818-928-162-53X; 172-704-659-215-126; 181-524-903-698-894; 182-919-703-822-902; 193-749-094-349-127,110,false,, -141-869-058-127-164,Thematic Evolution of Big Data in the Tourism and Hospitality Realm: A Descriptive Bibliometric Study Using Bibliometrix R - Tool,2023-07-14,2023,conference proceedings article,2023 World Conference on Communication & Computing (WCONF),,IEEE,,Ajit Kumar Singh; Manish Kumar; Pankaj Kumar Tyagi; Monika Rani; Anita Kumari Singh; Priyanka Tyagi,"This study aimed to explore the evolution and progression of Big Data studies in the tourism and hospitality industry. Through the use of two different periods, strategic diagrams, and a thematic evolution map, the study demonstrates the evolution of Big Data within this sector. The strategic diagram or thematic map utilizes two parameters, namely ""centrality"" and ""density,"" to depict the characteristics of themes in a two-dimensional space. Annual scientific output, methodology, authors, citations, and subject matter keywords are also explored. The research utilised Clarivate Analytics Web of Science as its data repository, and the R package bibliometrics was used to analyse and display its findings.",,,1,9,Realm; Thematic map; Big data; Tourism; Hospitality; Computer science; Thematic analysis; Descriptive statistics; Data science; Sociology; Geography; Statistics; Social science; Data mining; Mathematics; Qualitative research; Cartography; Archaeology,,,,,,http://dx.doi.org/10.1109/wconf58270.2023.10235141,,10.1109/wconf58270.2023.10235141,,,0,018-388-397-777-851; 026-030-439-870-098; 036-612-069-264-05X; 044-424-127-610-46X; 048-868-505-000-232; 051-528-572-767-641; 051-647-739-244-271; 051-669-371-103-151; 051-891-351-506-911; 104-194-201-921-535; 110-391-029-494-817; 147-247-785-855-08X; 147-635-479-553-635; 151-062-763-969-004; 192-565-610-409-42X,1,false,, -142-554-600-257-912,Análisis bibliométrico sobre la producción científica del trabajo social digital con Scopus y bibliometrix,,2020,journal article,Sinergias Educativas,,Grupo Compas,,,,,,,,,,,,,,http://dx.doi.org/10.37954/s.e.v6i1.164,,10.37954/s.e.v6i1.164,,,0,,1,true,cc-by-nc-sa,hybrid -142-655-090-180-347,Life cycle assessment and circular economy in the production of rare earth magnets: an updated and comprehensive review,2024-07-15,2024,journal article,Clean Technologies and Environmental Policy,1618954x; 16189558,Springer Science and Business Media LLC,Germany,Thamires Martinho Prados; Tiago Linhares Cruz Tabosa Barroso; Tânia Forster-Carneiro; Giancarlo Alfonso Lovón-Canchumani; Leda Maria Saragiotto Colpini,,27,2,471,494,Circular economy; Industrial and production engineering; Life-cycle assessment; Rare earth; Production (economics); Sustainable development; Engineering; Magnet; Environmental science; Natural resource economics; Mechanical engineering; Earth science; Economics; Political science; Geology; Biology; Ecology; Macroeconomics; Law,,,,,,http://dx.doi.org/10.1007/s10098-024-02935-7,,10.1007/s10098-024-02935-7,,,0,000-204-186-269-176; 000-940-541-194-574; 001-036-637-081-946; 001-733-615-308-381; 002-081-171-182-196; 002-229-580-212-42X; 002-336-761-024-94X; 002-539-535-600-881; 002-551-102-803-781; 002-736-785-475-000; 003-264-004-027-939; 003-547-320-965-169; 004-664-775-787-740; 005-416-920-522-292; 005-521-030-597-377; 007-376-856-212-861; 007-502-092-551-20X; 007-847-115-193-745; 008-489-014-223-828; 009-883-873-307-976; 010-319-181-276-003; 010-349-529-326-786; 010-562-646-960-615; 011-544-918-736-615; 012-068-068-943-109; 013-318-935-303-544; 014-565-733-114-459; 016-109-804-105-44X; 016-507-442-003-000; 016-796-667-382-164; 016-874-579-471-547; 017-288-688-253-981; 017-786-149-933-39X; 018-555-902-917-831; 018-802-586-693-922; 019-536-302-449-694; 019-557-974-798-179; 019-644-678-269-673; 019-646-552-070-166; 019-675-348-761-114; 020-102-115-768-507; 020-957-547-498-524; 021-178-464-536-234; 023-511-887-493-554; 023-699-799-743-514; 024-450-071-808-250; 024-469-323-544-707; 024-841-938-591-401; 025-063-987-756-418; 025-778-313-418-980; 026-591-128-884-388; 026-662-486-489-236; 028-875-361-981-464; 029-410-903-373-057; 030-027-471-058-734; 030-050-085-346-653; 030-102-345-627-219; 030-250-994-349-559; 030-665-708-999-986; 030-924-609-296-680; 032-096-256-750-703; 034-964-945-988-215; 035-652-040-621-893; 036-119-409-704-471; 036-706-135-710-335; 037-316-792-353-887; 037-537-229-050-720; 037-698-821-330-008; 038-471-298-001-495; 039-010-203-170-996; 039-024-931-642-223; 039-076-905-952-804; 039-398-088-716-087; 040-270-341-488-325; 040-525-866-294-058; 040-864-149-438-852; 041-082-313-487-85X; 041-614-789-048-056; 041-914-151-562-501; 041-948-042-355-883; 042-228-490-689-212; 042-424-616-668-678; 044-419-724-022-475; 044-441-969-653-575; 044-813-837-680-365; 044-915-665-018-291; 045-088-020-530-343; 045-519-894-711-235; 046-279-221-497-71X; 048-701-450-665-645; 048-729-806-481-156; 049-919-236-906-40X; 049-943-011-874-400; 051-671-359-989-968; 052-039-305-049-695; 053-718-607-482-575; 053-774-391-398-29X; 054-009-081-616-616; 054-075-291-851-724; 055-399-287-660-877; 056-975-807-902-585; 059-154-900-701-72X; 059-178-817-613-223; 060-112-574-490-751; 060-171-403-092-273; 061-961-365-462-757; 062-936-360-340-875; 063-590-773-293-633; 065-076-628-598-562; 066-015-764-833-093; 066-333-773-109-877; 067-506-942-202-263; 067-975-723-728-662; 069-768-157-641-909; 070-065-865-242-866; 070-591-003-852-935; 072-269-490-626-245; 073-961-049-964-873; 075-116-385-297-525; 076-095-941-155-576; 076-199-628-524-714; 076-715-136-405-485; 078-817-426-287-261; 078-834-609-035-467; 079-065-468-341-788; 079-515-171-788-461; 079-794-308-081-980; 079-928-195-279-966; 080-944-514-932-017; 081-765-531-963-694; 082-288-779-246-389; 084-134-163-570-296; 087-924-938-061-610; 088-485-458-656-855; 089-401-151-698-802; 089-532-413-951-91X; 089-547-008-878-685; 090-487-906-969-072; 095-835-630-509-349; 097-362-879-020-763; 097-796-194-250-839; 100-052-352-911-159; 101-492-445-903-188; 101-689-029-618-360; 102-300-672-465-939; 102-680-471-768-551; 102-916-532-332-750; 104-853-617-604-820; 105-436-716-474-32X; 107-095-661-197-854; 108-124-870-626-834; 108-400-576-720-57X; 109-026-690-342-858; 112-401-643-177-60X; 112-416-715-936-356; 113-548-956-955-807; 114-098-916-471-518; 114-951-565-886-994; 117-032-824-401-739; 120-164-080-483-630; 121-910-196-492-158; 123-853-084-078-053; 124-130-301-162-639; 127-281-647-214-093; 127-505-313-166-60X; 127-861-581-013-002; 128-114-609-403-705; 132-727-974-452-448; 133-416-082-535-596; 138-828-606-730-310; 140-565-250-693-028; 144-202-687-688-857; 145-190-096-627-359; 148-304-190-900-405; 148-577-158-396-759; 151-900-978-308-801; 153-989-330-109-814; 154-569-416-361-768; 155-785-355-093-52X; 157-168-458-461-427; 158-166-076-248-812; 159-209-155-589-694; 159-870-184-210-016; 162-489-597-179-366; 168-909-764-640-882; 173-536-210-548-525; 185-792-286-878-211; 186-949-794-777-352,0,false,, -142-846-589-011-341,A tale of PLS Structural Equation Modelling: Episode I— A Bibliometrix Citation Analysis,2022-09-01,2022,journal article,Social Indicators Research,03038300; 15730921,Springer Science and Business Media LLC,Netherlands,Enrico Ciavolino; Massimo Aria; Jun-Hwa Cheah; José Luis Roldán,"AbstractThe structure of knowledge about Structural Equation Modelling (SEM) based on the Partial Least Squares (PLS) estimator has been analysed by systematic and reproducible bibliometric citation analysis. This contribution aims to create a dynamic picture of the PLS-SEM research activity to support scholars with an enhanced understanding of the history, the present and the future directions of this fascinating modelling approach. Analysis was conducted using the Bibliometrix packageR with documents extracted (n = 3,854) from the Web of Science (WoS) database by Clarivate. Hence, we find seminal papers in the context of PLS-SEM as well as the diffusion and use in different research domains, suggesting new directions of applications. We also identify the collaboration networks involving authors and countries to highlight the new potential for cooperation from a co-authorship and international project standpoint. Furthermore, the dynamics of the sources indicate the interest of journals in this field in a dissemination role, which can assist authors in selecting a suitable publisher. Finally, the historiographic overview shows the dominant topics and the possible evolution in the citation analysis from the theoretical and application angles.",164,3,1323,1348,Structural equation modeling; Citation; Context (archaeology); Citation analysis; Data science; Computer science; Field (mathematics); Partial least squares regression; Estimator; Web of science; Bibliometrics; Quality of Life Research; Management science; Data mining; World Wide Web; Mathematics; Political science; Statistics; Engineering; MEDLINE; Geography; Archaeology; Medicine; Nursing; Machine learning; Pure mathematics; Law; Public health,,,,Università del Salento,https://link.springer.com/content/pdf/10.1007/s11205-022-02994-7.pdf https://doi.org/10.1007/s11205-022-02994-7,http://dx.doi.org/10.1007/s11205-022-02994-7,,10.1007/s11205-022-02994-7,,,0,000-797-545-448-405; 002-695-441-763-967; 002-841-201-171-498; 005-321-481-265-05X; 005-612-511-733-660; 007-290-499-250-431; 008-389-861-382-987; 011-057-105-680-492; 013-507-404-965-47X; 014-614-449-675-783; 015-692-170-714-052; 016-225-788-221-202; 017-300-737-144-757; 017-750-600-412-958; 019-105-811-166-815; 019-414-881-964-723; 020-449-904-644-059; 021-529-391-045-742; 022-904-479-736-781; 031-530-831-637-321; 032-578-325-185-86X; 032-946-061-922-067; 033-819-148-102-154; 035-332-377-211-731; 037-036-602-845-527; 037-815-640-424-494; 038-573-610-948-489; 043-139-008-972-530; 043-959-240-627-372; 044-685-744-601-943; 044-794-359-125-226; 046-992-864-415-70X; 047-134-478-431-993; 048-534-512-819-81X; 049-775-427-535-12X; 050-299-629-949-217; 051-220-952-620-00X; 051-865-643-777-765; 052-780-880-409-329; 053-272-790-663-185; 053-329-372-985-557; 059-743-657-952-371; 062-516-026-828-436; 062-948-580-981-656; 064-333-122-755-485; 066-270-452-456-725; 070-273-057-201-456; 072-813-199-606-608; 074-727-733-423-820; 074-781-837-430-563; 077-061-377-693-517; 078-779-082-793-384; 080-039-239-485-266; 080-100-940-508-948; 085-289-607-033-057; 086-061-636-673-34X; 090-304-568-302-982; 093-105-067-520-057; 097-830-869-280-400; 098-928-176-314-585; 099-781-807-153-216; 101-500-023-837-51X; 103-471-948-601-595; 104-664-046-935-26X; 106-883-315-183-565; 113-646-077-398-388; 115-947-417-668-519; 119-030-500-693-222; 129-324-374-869-536; 139-339-316-662-478; 143-875-130-007-110; 147-199-278-864-535; 148-181-357-978-726; 156-954-266-448-06X; 157-036-519-721-911; 158-093-496-145-778; 195-888-731-042-80X,42,true,cc-by,hybrid -142-884-100-580-74X,An open-source tool for merging data from multiple citation databases,2024-06-08,2024,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Dušan Nikolić; Dragan Ivanović; Lidija Ivanović,,129,7,4573,4595,Citation; Computer science; Database; Open source; Information retrieval; Data science; World Wide Web; Programming language; Software,,,,"Ministry of Science, Technological Development and Innovation",,http://dx.doi.org/10.1007/s11192-024-05076-2,,10.1007/s11192-024-05076-2,,,0,002-052-422-936-00X; 010-442-924-794-711; 013-507-404-965-47X; 013-683-191-846-68X; 017-146-468-093-265; 022-050-154-142-786; 023-739-624-312-986; 028-037-650-718-395; 030-184-036-846-700; 032-061-464-112-335; 033-755-041-647-285; 034-732-911-805-318; 044-776-532-451-668; 045-422-273-148-899; 045-797-416-772-535; 046-992-864-415-70X; 049-391-379-302-694; 060-110-039-971-60X; 064-400-499-357-900; 068-970-970-192-264; 069-764-890-140-842; 070-212-018-137-202; 070-708-457-505-15X; 078-328-702-196-714; 079-520-619-006-103; 081-523-568-781-26X; 089-884-554-780-711; 091-008-418-033-625; 098-377-939-800-955; 098-648-038-105-666; 098-660-367-734-393; 122-827-252-276-011; 123-202-581-406-928; 195-996-886-887-725,4,false,, -143-216-280-426-485,"Bibliometric Analysis: Comprehensive Insights into Tools, Techniques, Applications, and Solutions for Research Excellence",2025-01-05,2025,journal article,Spectrum of Engineering and Management Sciences,30093309,Scientific Oasis,,Rahul Kumar,"Bibliometric analysis has emerged as a vital methodology in understanding research landscapes through the application of statistical and quantitative techniques to academic literature. This study examines the evolution, significance, and application of bibliometric methods, highlighting their role in identifying influential authors, mapping collaboration networks, and uncovering emerging research trends. The analysis underscores the development of bibliometric tools, such as VOSviewer, CiteSpace, and Bibliometrix, and their diverse capabilities in visualizing and analyzing large datasets. By comparing bibliometric analysis with traditional review methodologies like systematic literature reviews and meta-analyses, this work illustrates its efficiency in providing comprehensive insights into research domains while emphasizing its complementary role in a holistic research approach. Through the lens of key challenges and advancements in bibliometric tools and methodologies, this research highlights its indispensable role in shaping academic, policy, and institutional strategies in a data-driven era.",3,1,45,62,Excellence; Data science; Bibliometrics; Management science; Computer science; Engineering ethics; Political science; Library science; Engineering; Law,,,,,,http://dx.doi.org/10.31181/sems31202535k,,10.31181/sems31202535k,,,0,,6,false,, -143-344-379-253-875,Caryocaraceae Voigt (Malpighiales): a Synthesis Based on Science Mapping and Systematic Review,2020-10-22,2020,journal article,The Botanical Review,00068101; 18749372,Springer Science and Business Media LLC,United States,Rhewter Nunes; Natácia E. Lima; Rafael Barbosa Pinto; Ivone de Bem Oliveira; Mariana Pires de Campos Telles,,86,3,338,358,Sociology of scientific knowledge; Geography; Data science; Malpighiales; Anthodiscus; Caryocar; Caryocaraceae; Ecology (disciplines); Traditional knowledge; Scopus,,,,,https://link.springer.com/article/10.1007/s12229-020-09233-z,http://dx.doi.org/10.1007/s12229-020-09233-z,,10.1007/s12229-020-09233-z,3094463324,,0,000-116-932-303-074; 000-420-031-470-066; 001-128-175-901-118; 001-851-676-793-699; 002-138-920-913-027; 004-046-860-084-70X; 005-520-026-022-656; 005-581-970-386-240; 005-600-121-002-741; 005-934-195-690-84X; 007-719-616-908-060; 009-554-109-357-735; 011-017-506-725-667; 012-344-647-402-671; 013-507-404-965-47X; 016-094-463-058-411; 016-801-472-844-537; 017-659-110-692-347; 017-920-697-684-325; 021-205-770-272-08X; 024-736-800-538-507; 025-434-435-354-63X; 025-900-020-063-879; 027-896-023-963-198; 028-215-170-540-208; 028-384-961-442-062; 028-944-206-004-010; 029-916-050-187-735; 030-324-260-975-541; 033-212-295-141-806; 033-466-612-854-202; 033-511-140-888-569; 033-914-229-590-829; 034-142-608-984-907; 035-642-373-075-529; 037-094-627-771-662; 039-977-235-591-875; 040-430-609-722-144; 041-620-297-313-555; 041-873-446-176-503; 044-077-170-965-270; 044-177-083-647-74X; 046-992-244-613-449; 048-113-539-702-042; 051-883-644-160-379; 052-920-345-079-921; 053-258-164-516-400; 056-426-226-149-95X; 058-923-618-930-227; 061-329-260-035-311; 062-582-527-766-443; 065-637-509-604-752; 069-744-510-316-300; 071-519-339-481-920; 071-813-199-746-794; 072-702-194-567-994; 077-716-729-274-119; 078-964-558-715-969; 080-903-971-126-60X; 092-120-695-322-43X; 094-780-188-151-548; 095-771-556-088-290; 095-840-138-610-361; 099-449-797-501-234; 101-629-655-490-54X; 107-260-956-264-096; 109-313-323-939-363; 109-456-855-567-108; 115-912-017-164-979; 116-155-050-289-483; 116-747-746-193-921; 116-791-135-428-603; 118-377-863-712-628; 120-413-135-348-933; 144-084-538-137-109; 149-076-698-393-357; 150-257-492-614-36X; 151-499-538-511-840; 152-258-498-862-45X; 153-338-355-805-913; 160-978-806-154-11X; 170-336-013-910-948; 174-300-678-844-931; 192-089-122-522-867; 193-219-260-413-182,1,false,, -143-419-427-198-107,Neurodidactics and vocabulary acquisition in Cuban teacher trainees: Emerging trends,2024-12-05,2024,journal article,Bulletin of the Transilvania University of Brasov. Series IV: Philology and Cultural Studies,20667698; 2066768x,Universitatea Transilvania Brasov,,Damarys Romero Enriquez,"This study deals with the emerging field of neurodidactics and its implications for vocabulary acquisition. More precisely, the article presents a bibliometric analysis of a dataset comprising 32 papers from 24 sources, spanning the period from 2011 to 2023. The data were acquired from Web of Science and analyzed using the R-Bibliometrix package. The study identifies research trends, emerging and interdisciplinary areas, as well as citation factors, providing also a brief overview of the current state of vocabulary acquisition in Cuban language teaching in general, and in teacher training in particular. It aims to offer a global perspective on neurodidactics and an overview of its impact on vocabulary learning in the Cuban higher education system. Additionally, it identifies research gaps and suggests avenues for future studies and educational innovations.",,,43,62,Vocabulary; Citation; Perspective (graphical); Field (mathematics); Computer science; Mathematics education; Data science; Psychology; Library science; Linguistics; Artificial intelligence; Philosophy; Mathematics; Pure mathematics,,,,,https://webbut.unitbv.ro/index.php/Series_IV/article/download/8580/6087 https://doi.org/10.31926/but.pcs.2024.66.17.1.4,http://dx.doi.org/10.31926/but.pcs.2024.66.17.1.4,,10.31926/but.pcs.2024.66.17.1.4,,,0,,0,true,,bronze -143-442-137-422-209,Conceptual structure analysis with Bibliometrix package in R: A scientific communication of sport education,2023-12-02,2023,journal article,Retos,19882041; 15791726,JURUFRA SL,Spain,Hanny Hafiar; Heru Ryanto Budiana; Ira Mirawati; Khairul Hafezad Abdullah; Eko Purnomo,"Many studies on sports education have been conducted, some of which are published and disseminated through scientific journals. Publication by scientific journals is a part of scientific communication. It demands a review of the existing research to understand the conceptual structure of certain studies, especially the time they intersect with one another, such as sports education. In the database, sport education articles are commonly categorized into the subject of Education & Educational Research and/or Sport Sciences. This study aimed to obtain an overview of the similarities and differences in the conceptual structure of sport education studies included in the subject of Education & Educational Research and Sport Sciences. It employed a database from the Web of Science using the bibliometric method. Bibliometric analysis was performed with Bibliometric Package, a Built-in R tool. One of our key findings lies in the similarities and differences between the two. We also explored some implications in the discussion section. This paper completed the existing kinds of literature with additional insights for researchers and practitioners of sports education to consider and find future research directions. The results suggested similarities and differences in mapping between the two subjects, including timespans, percentages of annual growth rate, average ages, average citations per doc, references, keywords, and international collaboration.; Keywords: bibliometric analysis; conceptual structure; scientific communication; sports education; Sport Sciences.",51,,1245,1254,Subject (documents); Sports science; Web of science; Physical education; Bibliometrics; Section (typography); Sociology; Psychology; Mathematics education; Library science; Computer science; Political science; MEDLINE; Law; Operating system,,,,,https://recyt.fecyt.es/index.php/retos/article/download/101298/75039 https://doi.org/10.47197/retos.v51.101298 https://dialnet.unirioja.es/descarga/articulo/9207698.pdf https://dialnet.unirioja.es/servlet/oaiart?codigo=9207698,http://dx.doi.org/10.47197/retos.v51.101298,,10.47197/retos.v51.101298,,,0,,2,true,cc-by,gold -143-637-835-355-971,Asian business and management: review and future directions.,2022-11-04,2022,editorial,Asian business & management,14769328; 14724782,Springer Science and Business Media LLC,United Kingdom,Fabian Jintae Froese; Ashish Malik; Satish Kumar; Saumyaranjan Sahoo,"This century has been proclaimed the Asian century, as industrialised countries such as Japan, Singapore, and South Korea, along with rapidly emerging nations such China and India, have contributed to worldwide economic growth. In response, research has analysed the reasons why Asian business and management have found such success. Based on a bibliometric analysis of Asian Business & Management (ABM), a premier journal devoted to Asian management, here we examine the performance of the research constituents, social structure, and intellectual structure of 331 scholarly papers, which sheds light on the growing influence of ABM through six major knowledge clusters: corporate social responsibility; business management in emerging markets; corporate governance; internationalization; political and business ties; and organization culture and performance. Temporal analysis reveals the emergence of strategy and human resource management as a distinct knowledge cluster and the increasing importance of China as a research context and producer. Based on this analysis, we propose future research directions.",21,5,657,689,Internationalization; China; International business; Context (archaeology); Corporate governance; Emerging markets; Asian culture; Human resource management; Strategic management; Corporate social responsibility; Asian studies; Politics; Business; Political science; Public relations; Sociology; Economics; Management; Marketing; International trade; Geography; Ethnology; Archaeology; Finance; Law,Asian business and management; Bibliometric analysis; Bibliometrics; Review,,,Georg-August-Universität Göttingen,https://link.springer.com/content/pdf/10.1057/s41291-022-00209-y.pdf https://doi.org/10.1057/s41291-022-00209-y,http://dx.doi.org/10.1057/s41291-022-00209-y,40477764,10.1057/s41291-022-00209-y,,PMC9638335,0,007-254-721-555-052; 013-507-404-965-47X; 015-098-755-676-90X; 015-349-856-791-214; 019-312-463-514-685; 019-943-172-927-659; 021-064-056-079-788; 027-123-536-258-975; 029-941-797-463-763; 033-783-181-057-98X; 033-971-548-281-995; 034-377-208-841-225; 038-965-362-971-85X; 041-967-847-561-389; 043-545-425-005-174; 045-516-979-289-244; 046-992-864-415-70X; 056-690-811-230-444; 059-486-691-840-811; 064-222-516-406-315; 075-327-152-202-070; 081-115-240-125-573; 087-255-710-316-116; 087-925-774-144-464; 088-315-961-386-766; 090-028-209-266-424; 103-214-949-434-277; 103-515-124-208-805; 104-414-560-866-795; 108-633-170-184-911; 122-029-749-654-173; 127-393-600-280-110; 139-651-462-073-918; 141-529-093-432-892; 142-715-265-427-770,13,true,cc-by,hybrid -143-641-870-539-524,Corporate Social Responsibility Trends in the Airline Industry: A Bibliometric Analysis,2024-03-26,2024,journal article,Sustainability,20711050,MDPI AG,Switzerland,Kaisa Sorsa; Carolina Bona-Sánchez,"The aim of this study is to perform a bibliometric analysis of corporate social responsibility (CSR) research in the airline industry, underscoring current developments and future trends. Utilizing open-source R software (version 4.2.3), including the Bibliometrix R library (version 4.1.4) and VOSviewer (version 1.6.20), this study notes a significant rise in CSR research. It highlights influential studies, leading scholars, and key journals in the field. The co-word analysis shows CSR’s impact on efficiency, value, employee perceptions, and customer loyalty. Post-COVID trends indicate an expanded focus on health, safety, and environmental, social, and governance (ESG) factors. The research suggests a shift towards integrated CSR strategies in the airline industry, emphasizing sustainability, stakeholder inclusion, and transparent reporting. This shift marks a movement towards more comprehensive and effective CSR approaches in stakeholder communication.",16,7,2709,2709,Corporate social responsibility; Business; Social responsibility; Accounting; Political science; Public relations,,,,,https://www.mdpi.com/2071-1050/16/7/2709/pdf?version=1711435073 https://doi.org/10.3390/su16072709 https://accedacris.ulpgc.es/jspui/bitstream/10553/129963/1/sustainability-16-02709.pdf https://hdl.handle.net/10553/129963,http://dx.doi.org/10.3390/su16072709,,10.3390/su16072709,,,0,002-052-422-936-00X; 006-293-692-390-548; 013-123-944-981-275; 013-205-371-955-051; 013-507-404-965-47X; 015-118-657-194-603; 015-628-088-610-602; 015-683-564-587-696; 016-664-829-067-972; 017-750-600-412-958; 020-191-135-286-81X; 020-552-236-958-890; 023-180-872-176-018; 024-379-225-419-25X; 027-449-836-409-501; 034-928-960-360-735; 034-982-314-482-620; 039-968-375-718-706; 040-648-564-012-342; 042-476-047-584-902; 050-731-606-405-196; 051-252-080-245-586; 054-008-039-948-954; 055-206-850-336-010; 055-222-575-590-371; 055-932-088-973-216; 058-872-161-447-886; 059-969-527-886-486; 060-028-945-004-90X; 060-743-648-754-416; 064-085-377-027-092; 064-264-695-662-36X; 066-137-637-286-280; 070-991-282-066-330; 073-210-383-876-855; 073-286-306-987-069; 077-319-417-493-831; 083-742-145-849-480; 084-915-932-802-752; 085-566-316-023-070; 086-499-544-038-986; 087-543-480-663-978; 096-965-861-200-404; 101-501-839-123-629; 103-772-391-467-091; 106-671-549-147-001; 107-150-172-527-41X; 111-481-369-852-532; 116-850-405-772-031; 117-560-326-221-523; 128-100-581-455-505; 128-951-437-364-110; 131-650-044-879-729; 133-897-893-324-581; 135-784-892-667-103; 139-641-412-398-758; 139-966-927-583-456; 141-228-727-694-124; 151-817-357-409-733; 162-049-241-402-716; 167-044-586-531-299; 173-008-879-637-846; 179-478-724-261-64X; 192-078-298-658-852,4,true,,gold -143-735-661-822-857,Wearable Devices in Healthcare Services. Bibliometrix Analysis by using R Package,2022-06-28,2022,journal article,International Journal of Online and Biomedical Engineering (iJOE),26268493,International Association of Online Engineering (IAOE),,null Javed Ali; null Ahmad Jusoh; null Norhalimah Idris; null Awais Gul Airij; null Rabia Chandio,"Purpose: The current study aims at exploring the theme – wearable devices in healthcare services from 2008 to 2021. It intends to identify the most prominent sources, authors, affiliations, countries, documents, words and trend topics. ; Methodology: Total 204 records have been extracted from Scopus after applying inclusion and exclusion criteria, and analysed by using biblioshiny software of R-package. ; Findings: Results of bibliometrix analysis show the prominent sources in ‘wearable devices & healthcare’ search are IEEE Access and Sensors (Switzerland). Moreover, Lee S. and Shen J. are found be the most productive and prolific authors, King Saud University is leading institutions in producing the articles, China, South Korea, India and USA are identified as the most productive countries and Network Security, Cryptography, Deep Learning, Healthcare Application and Healthcare System are found to be the trending topics and themes in the year 2021. ; Originality: This study presents the deep analytics regarding wearable devices in healthcare services and it also suggests useful future research avenues and insights for researchers and practitioners.",18,8,61,86,Health care; Wearable computer; Scopus; Wearable technology; Computer science; Inclusion and exclusion criteria; Inclusion (mineral); Data science; Business; World Wide Web; Knowledge management; Medicine; MEDLINE; Political science; Sociology; Alternative medicine; Social science; Law; Embedded system; Pathology,,,,,https://online-journals.org/index.php/i-joe/article/download/31785/11567 https://doi.org/10.3991/ijoe.v18i08.31785,http://dx.doi.org/10.3991/ijoe.v18i08.31785,,10.3991/ijoe.v18i08.31785,,,0,,4,true,,gold -143-780-360-714-054,Enseñanza de la estructura espacio-tiempo: un análisis bibliométrico (1988-2020) y futuras direcciones de investigación,2021-06-01,2021,,,,,,Juan Terán; Gionara Tauchen; Hebert Lobo,"espanolSe efectuo un analisis bibliometrico de la produccion cientifica con fines educativos, en todos los niveles, sobre la estructura del espacio-tiempo, para reconstruir la estructura intelectual, conceptual y de redes sociales de la comunidad cientifica implicada, en el periodo 1988 hasta agosto del 2020. La informacion se obtuvo de las bases de datos Web of Science, rastreando los valores logicos “spacetime and teaching” o “spacetime and pedagogical”, totalizando ciento catorce articulos. Se siguio la metodologia del analisis bibliometrico descriptivo. Los resultados y el analisis se muestran con Bibliometrix, una herramienta de codigo abierto para la investigacion cuantitativa en cienciometria y bibliometria. Se concluyo que la estructura del espacio-tiempo esta fuertemente presente en la relatividad general, teoria cuantica y en las soluciones de Schwarzschild y que los modelos pedagogicos estan relacionados con los topicos de la teoria de campos cuanticos, mientras que la ensenanza la fisica busca comprender la estructura del espacio tiempo en la teoria especial y general de la relatividad. EnglishA bibliometric analysis of scientific production was carried out for educational purposes, at all levels, on the structure of space-time, to reconstruct the intellectual, conceptual and social network structure of the scientific community involved, in the period 1988 to August of 2020. The information was obtained from the Web of Science databases, tracking the logical values ""spacetime and teaching"" or ""spacetime and pedagogical"", totaling one hundred and fourteen articles. The descriptive bibliometric analysis methodology was followed. Results and analysis are displayed with Bibliometrix, an open-source tool for quantitative research in scientometry and bibliometrics. It was concluded that the structure of space-time is strongly present in general relativity, quantum theory and in Schwarzschild solutions and that pedagogical models are related to the topics of quantum field theory, while teaching physics seeks to understand the structure of spacetime in the special and general theory of relativity.",33,1,47,59,Humanities; Scientific production; Bibliometric analysis; Web of science,,,,,https://dialnet.unirioja.es/servlet/articulo?codigo=8070438 https://doaj.org/article/42d55d72c231466eb2f2ce0f1cf5819b,https://dialnet.unirioja.es/servlet/articulo?codigo=8070438,,,3178592020,,0,,0,false,, -144-097-961-517-910,Bibliometric Analysis of 21st Century Skills in Practical Laboratory Learning Research Trends from 1986 to 2023 Using RStudio Bibliometrix and VOSViewer Software Tools,2024-07-03,2024,journal article,KnE Social Sciences,2518668x,Knowledge E DMCC,,Febrian Andi Hidayat; Ida Kaniawati; Andi Suhandi; Hernani Hernani; Lisa Dewi Ramadany,"The acceleration of technological advancements and globalization underscores the importance of 21st-century skills in practical learning contexts. This manuscript presents a comprehensive bibliometric analysis of scholarly publications from 1986 to 2023, delineating the evolution and trends of research in 21st-century skills within practical learning environments. Utilizing the robust capabilities of RStudio’s Bibliometrix and VOSviewer tools, we systematically quantify and visualize the data, providing a metaanalysis of the existing literature. Our analysis encompasses publication output, citation patterns, keyword frequency, thematic concentrations, and collaborative networks. We reveal significant growth in research interest, particularly in areas such as critical thinking, collaboration, communication, and creativity, often referred to as the “4 Cs” of 21st-century skills. The study identifies key authors, influential institutions, and pivotal publications that have shaped the discourse. Moreover, it highlights interdisciplinary collaborations and the geographical distribution of contributions, offering insights into the global research landscape. Our findings suggest that practical learning pedagogies are increasingly integrating 21st-century competencies, reflecting a paradigm shift towards skills that prepare students for the demands of the modern workforce and society. This work not only serves as a barometer for past and present research trajectories but also provides a scaffold for future inquiries in the domain of practical and experiential education.; Keywords: bibliometric analysis, 21st century skills, practical laboratory learning, vosviewer, rstudio",,,,,Experiential learning; 21st century skills; Creativity; Globalization; Thematic analysis; Data science; Engineering ethics; Knowledge management; Engineering; Sociology; Computer science; Social science; Psychology; Political science; Pedagogy; Qualitative research; Social psychology; Law,,,,,https://knepublishing.com/index.php/KnE-Social/article/view/16523/26350 https://doi.org/10.18502/kss.v9i19.16523,http://dx.doi.org/10.18502/kss.v9i19.16523,,10.18502/kss.v9i19.16523,,,0,000-054-534-616-744; 002-052-422-936-00X; 004-334-051-172-239; 005-326-855-311-640; 007-398-557-019-102; 010-442-924-794-711; 012-450-422-737-218; 016-990-421-483-167; 027-677-880-203-53X; 029-092-521-432-268; 029-340-554-088-168; 035-731-372-956-345; 044-309-054-139-588; 053-878-034-407-270; 055-386-616-188-25X; 085-001-502-383-40X; 088-144-658-345-861; 116-339-119-777-116; 125-356-115-566-021; 126-788-554-161-881; 135-058-721-379-186; 143-671-707-733-762; 196-846-214-555-536,1,true,,gold -144-321-172-773-173,Global research on nanomaterials for liver cancer from 2004 to 2023: a bibliometric and visual analysis.,2024-12-26,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Yitao Fan; Han Xiao; Yan Wang; Shuhan Wang; Hui Sun,"Primary liver cancer, particularly hepatocellular carcinoma, is one of the most common gastrointestinal cancers. An increasing number of studies indicate that nanomaterials play a significant role in the diagnosis and treatment of liver cancer. However, despite the extensive and diverse research on nanomaterials and liver cancer, bibliometric studies in this field have not yet been reported. This study aims to comprehensively evaluate the application prospects and development trends of nanomaterials in primary liver cancer over the past 20 years. By elucidating the current state of research on liver cancer, we intend to provide valuable reference information for researchers in this field.; We conducted a comprehensive search of the Web of Science Core Collection for publications related to liver cancer and nanomaterials from January 1, 2004, to December 31, 2023. Relevant literature was selected based on specific inclusion and exclusion criteria. These selected publications were subsequently analyzed using CiteSpace, VOSviewer, and the R package ""bibliometrix"" to identify trends, influential countries, institutions, authors, journals, and research hotspots in this field.; This study included a total of 1641 publications, with an annual growth rate of 25.45%. China and the United States are leading in this field, accounting for 67.46% and 11.27% of the total publications, respectively. The Chinese Academy of Sciences and Shao D are the most cited institution and author, respectively. The International Journal of Nanomedicine is the most influential journal in this field, while Biomaterials is the most highly cited and co-cited journal. Research hotspots mainly focus on improving drug delivery efficiency, inducing cancer cell apoptosis, photodynamic therapy, photothermal therapy, and combination treatments. Emerging research directions include the tumor microenvironment, polyethylene glycol, and immunogenic cell death.; The results of this study indicate that the application of nanomaterials in the field of liver cancer is gradually becoming a significant research area, with a focus on improving drug delivery efficiency, enhancing therapeutic efficacy, and reducing side effects.; © 2024. The Author(s).",15,1,838,,Liver cancer; Web of science; Bibliometrics; Medicine; Cancer; Political science; Library science; MEDLINE; Internal medicine; Computer science; Law,Bibliometrics; CiteSpace; Drug delivery; Liver cancer; Nanomaterials; Nanoparticles; VOSviewers,,,Talent Introduction Plan of the Lanzhou University Second Hospital (yjrckyqdj-2022-01); National Natural Science Foundation of China (32070138); National Natural Science Foundation of China (82060105); The Central University Excellent Youth Team Project (lzujbky-2023-eyt04),,http://dx.doi.org/10.1007/s12672-024-01735-1,39722094,10.1007/s12672-024-01735-1,,PMC11669646,0,001-817-292-247-905; 002-052-422-936-00X; 005-310-002-775-228; 006-317-921-975-093; 006-679-766-915-119; 007-072-850-521-126; 007-500-155-247-91X; 011-145-636-290-223; 011-364-541-838-073; 012-497-328-331-068; 013-507-404-965-47X; 013-537-690-457-958; 013-933-054-857-437; 020-286-394-051-646; 020-325-503-894-538; 021-874-066-790-690; 022-301-279-920-83X; 024-076-887-041-42X; 024-556-758-949-100; 024-867-781-177-338; 025-019-671-640-98X; 026-330-227-640-113; 026-559-148-976-407; 027-706-572-565-168; 029-442-715-497-104; 029-493-500-662-539; 030-199-275-660-542; 030-333-817-997-583; 030-429-921-961-755; 030-935-383-180-549; 033-942-414-434-914; 041-435-896-633-062; 044-993-533-403-415; 046-060-026-030-763; 048-817-727-028-943; 049-888-372-215-196; 050-713-678-402-69X; 050-876-517-536-212; 053-935-641-259-212; 054-818-565-070-154; 055-719-908-628-563; 055-812-990-696-405; 056-672-571-002-573; 058-142-801-003-868; 058-362-367-638-741; 058-987-553-422-59X; 061-670-699-577-749; 062-154-605-652-29X; 062-633-089-780-401; 064-238-673-831-40X; 064-400-499-357-900; 067-215-330-719-325; 070-108-103-742-095; 074-294-643-782-239; 075-355-522-529-459; 077-274-093-965-84X; 077-683-026-160-598; 078-844-256-606-71X; 080-085-367-121-376; 083-366-317-004-681; 085-945-966-064-544; 086-988-369-969-202; 088-332-071-935-959; 089-900-449-985-368; 091-488-510-013-42X; 092-062-550-269-321; 092-566-598-283-519; 095-116-580-336-978; 095-483-279-590-576; 095-603-042-363-563; 097-074-045-917-439; 100-609-227-350-394; 100-998-305-015-009; 102-200-899-000-089; 104-406-825-565-980; 105-679-043-867-407; 106-070-477-406-743; 110-077-417-791-535; 130-173-026-987-894; 131-877-880-900-024; 131-941-603-484-820; 136-061-830-742-865; 141-390-850-427-158; 142-754-931-646-337; 147-833-510-312-619; 151-173-193-593-165; 153-454-599-489-847; 165-335-281-856-380; 170-725-599-989-815; 187-321-147-346-671; 193-869-495-175-611,2,true,cc-by,gold -145-110-914-964-355,Bibliographic Analysis of Mindfulness Concept in Marketing Literature,,2023,journal article,Florya Chronicles of Political Economy,21495750; 27177629,Istanbul Aydin University,,İlkay KARADUMAN,"In this study, the bibliographic analysis was used to examine the publications that relate marketing to the approach of mindfulness, which has been on the agenda in recent years in the literature, especially in the fields of psychology and health care.The study examined publications in the Web of Science Core Collection Database.291 publications originating between 1990 and March 2023 were included in the study.The quality of the collected data was first assessed in the analyzes performed with the Biblioshiny software using the R Based Bibliometrix database.Then publication trends, country analyzes, keyword analyzes, and topic analyzes were performed.The results of the study show that the philosophy and practices of mindfulness are becoming increasingly important in the field of marketing.The results of the study are relevant to both marketing practitioners and marketing scholars.",9,1,1,13,Mindfulness; Psychology; Marketing; Business; Psychotherapist,,,,,https://dergipark.org.tr/tr/download/article-file/3030722 https://dergipark.org.tr/tr/pub/fcpe/issue/76881/1269835,http://dx.doi.org/10.17932/iau.fcpe.2015.010/fcpe_v09i1001,,10.17932/iau.fcpe.2015.010/fcpe_v09i1001,,,0,,0,true,,gold -145-778-047-681-700,Research trends on the relationship between air pollution and cardiovascular diseases in 2013-2022 - A scientometric analysis.,2023-07-31,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Daitian Zheng; Qiuping Yang; Jinyao Wu; Huiting Tian; Zeqi Ji; Lingzhi Chen; Jiehui Cai; Zhiyang Li; Yexi Chen,"Exposure to air pollution is linked with an elevated risk of cardiovascular diseases (CVDs) and CVDs-related mortality. However, there is a shortage of scientometric analysis on this topic. Therefore, we propose a scientometric study to explore research hotspots and directions in this topical field over the past decade. We used the core collection of Web of Science (WoS) to obtain relevant publications and analyzed them using Excel, the Bibliometix R-package, CiteSpace, and VOSviewer. The study covered various aspects such as annual publications, highly cited papers, co-cited references, journals, authors, countries, organizations, and keywords. Research on air pollution and CVDs has remarkable increase over the past decade, with notable researchers including Kan H, Brook RD, Peters A, and Schwartz J. The 3144 articles were published by 4448 institutions in 131 countries/regions. The leading countries were the USA and China, and the most published journal was Environmental Research. Mortality, hospital admissions, oxidative stress, inflammation, long-term exposure, fine particulate matter, and PM2.5 are the top areas that merit further investigation and hold significant potential for advancing our understanding of the complex relationship between air pollution and CVDs.",30,41,93800,93816,Air pollution; China; Particulates; Environmental health; Economic shortage; Web of science; Library science; Regional science; Geography; Environmental planning; Environmental science; Medicine; Political science; MEDLINE; Ecology; Computer science; Linguistics; Philosophy; Archaeology; Government (linguistics); Law; Biology,Air pollution; Bibliometrix; Cardiovascular diseases; CiteSpace; Scientometric; VOSviewer,Humans; Cardiovascular Diseases/epidemiology; Air Pollution; China; Hospitalization; Inflammation,,"Special Fund Project for Science and Technology Innovation Strategy of Guangdong Province (210728156901524); Special Fund Project for Science and Technology Innovation Strategy of Guangdong Province (210728156901519); the Medical Scientific Research Foundation of Guangdong Province, China (A2021432); the Medical Scientific Research Foundation of Guangdong Province, China (A2023481); the Shantou Medical Health Science and Technology Plan (210521236491457); the Shantou Medical Health Science and Technology Plan (210625106490696); the Shantou Medical Health Science and Technology Plan (220518116490772); the Shantou Medical Health Science and Technology Plan (220518116490933)",https://www.researchsquare.com/article/rs-2793736/latest.pdf https://doi.org/10.21203/rs.3.rs-2793736/v1,http://dx.doi.org/10.1007/s11356-023-28938-3,37523085,10.1007/s11356-023-28938-3,,,0,001-612-057-525-54X; 002-052-422-936-00X; 002-435-134-891-554; 002-467-039-425-287; 003-967-985-881-075; 007-167-844-439-304; 011-064-754-825-538; 013-507-404-965-47X; 014-880-935-437-619; 020-425-603-019-632; 021-034-279-318-064; 021-063-930-704-996; 021-210-503-825-651; 021-787-712-787-168; 023-251-779-540-319; 023-668-271-980-114; 025-084-070-446-808; 025-325-756-305-895; 027-026-873-619-570; 027-392-613-466-969; 027-562-807-161-505; 033-755-041-647-285; 038-441-595-290-660; 040-550-293-662-566; 040-814-703-694-648; 042-469-764-181-713; 044-647-775-319-871; 044-743-000-324-544; 045-368-114-501-494; 049-820-565-367-590; 054-798-151-839-781; 055-875-405-217-003; 059-422-048-277-262; 059-597-497-948-409; 060-083-901-102-083; 061-538-402-818-954; 062-031-099-770-145; 062-692-807-278-820; 064-400-499-357-900; 064-482-912-103-288; 065-256-707-303-548; 068-364-667-604-852; 069-511-868-544-95X; 078-260-691-609-924; 085-926-501-732-203; 089-214-406-369-952; 094-010-147-760-40X; 098-526-336-836-138; 098-553-995-906-244; 108-763-698-105-455; 112-810-689-535-289; 122-415-544-444-960; 172-544-600-341-937,4,true,,green -145-993-271-753-854,Green Finance: A Bibliometrix Application,2024-03-14,2024,journal article,Text Analytics in Economics,30471222,Sharia Economic Applied Research and Training (SMART) Insight,,Amelia Tri Puspita,"Over the past 30 years, capital market debt has developed and grown rapidly around the world especially in Europe, Latin America and Asia. This capital market debt is usually used to fulfill development needs and other large projects in a country. Nowadays, capital market debt is needed for green projects that emphasize the concept of environmental friendliness. This is called green finance, where capital market debt is more utilized for projects that are concerned with the environment and sustainable development. This study aims to determine the development map and trend of Green Finance published by reputable journals in the field of Economics and finance. The data analyzed were more than 416 Scopus indexed research publications. The export data was then processed and analyzed using the R Biblioshiny application program to determine the bibliometric map of Green Finance development. The results showed that the number of publications on the development of the role of economic and financial research continues to increase.",1,1,,,Business; Finance,,,,,https://journals.smartinsight.id/index.php/TAE/article/download/448/421 https://doi.org/10.58968/tae.v1i1.448,http://dx.doi.org/10.58968/tae.v1i1.448,,10.58968/tae.v1i1.448,,,0,,0,true,cc-by-nc,hybrid -146-231-354-131-431,biblioverlap: an R package for document matching across bibliographic datasets,2024-06-08,2024,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Gabriel Alves Vieira; Jacqueline Leta,,129,7,4513,4527,Information retrieval; Matching (statistics); Computer science; R package; Data science; Data mining; Statistics; Mathematics; Computational science,,,,Conselho Nacional de Desenvolvimento Científico e Tecnológico,,http://dx.doi.org/10.1007/s11192-024-05065-5,,10.1007/s11192-024-05065-5,,,0,000-632-377-268-396; 003-790-583-894-155; 005-282-534-739-716; 009-793-385-068-604; 011-336-473-093-736; 013-507-404-965-47X; 014-683-170-888-596; 014-982-591-411-278; 015-008-828-329-940; 015-951-011-553-339; 020-298-213-810-681; 026-933-264-520-738; 027-690-220-065-414; 028-037-650-718-395; 034-732-911-805-318; 043-496-301-696-550; 044-776-532-451-668; 044-971-180-072-43X; 045-422-273-148-899; 045-797-416-772-535; 050-667-413-498-468; 051-905-317-081-07X; 064-354-744-911-692; 076-468-389-542-669; 078-832-571-030-02X; 095-614-160-599-685; 107-276-900-991-821; 108-065-110-176-845; 108-691-278-486-183; 110-742-040-134-873; 122-940-758-812-429; 141-562-203-874-638; 147-921-330-257-464; 151-066-640-236-837; 159-825-640-996-380; 167-148-923-567-724; 185-577-812-919-481; 186-624-831-982-035; 193-109-529-207-182,1,false,, -146-335-752-697-795,Pemetaan dan Analisis Bibliometrik Tren Penelitian: Manajemen Diseminasi Informasi di Scopus tahun 2018-2023 dengan VOSviewer dan RStudio Bibliometrix,2024-12-12,2024,journal article,Tik Ilmeu : Jurnal Ilmu Perpustakaan dan Informasi,25803662; 25803654,STAIN Curup,,Ayunda Trisna Ludi Tiara; Tamara Adriani Salim; Muhamad Prabu Wibowo,"Penelitian ini dimaksudkan untuk mengkaji perkembangan topik manajemen diseminasi informasi, dengan tujuan untuk mengetahui: (1) Bagaimana jumlah perkembangan publikasi ilmiah internasional mengenai topik manajemen diseminasi informasipada tahun 2018 - 2023 di Scopus; (2) Berapa banyak jumlah jurnal inti dalam publikasi internasional pada topik manajemen diseminasi informasipada tahun 2018 - 2023 di Scopus; (3) Bagaimana peta perkembangan publikasi internasional penelitian topik manajemen diseminasi informasiberdasarkan kata kunci pada tahun 2018 - 2023 di Scopus. Pengumpulan data dengan melakukan penelusuran melalui Scopus dengan kata kunci dan filtrasi data yang telah disesuaikan kebutuhan. Subjek dianalisis dan divisualisasikan dengan Microsoft Excel, Scopus Result Analyzer, VOSviewer, dan Rstudio (Bibliometrix) . Hasil penelitian menunjukkan bahwa tren perkembangan topik manajemen diseminasi informasipada tahun 2018 hingga 2023 di Scopus mengalami puncaknya pada tahun 2020 dengan jumlah artikel sebanyak 204 artikel. Sedangkan penerbit Jurnal Inti dengan peringkat satu adalah Jurnal BMJ Open yang menerbitkan 80 artikel pada topik manajemen diseminasi informasi. Hasil pemetaan memberikan gambaran bahwasanya topik ini memiliki potensi berkembang apabila ada proses pengembangan strategi yang tepat, banyak hal juga yang mempengaruhi efisiensi penyebaran informasi termasuk suatu fenomena yang signifikan seperti pandemic. Untuk penelitian selanjutnya peneliti dapat memberikan saran agar organisasi manajemen diseminasi informasi meningkatkan pemahaman terhadap fluktuasi tren publikasi, memperluas cakupan geografis, kolaborasi lintas sektor, dan fokus pada kecepatan serta adaptabilitas dalam menghadapi tantangan",8,2,267,282,Scopus; Political science; MEDLINE; Law,,,,,,http://dx.doi.org/10.29240/tik.v8i2.9776,,10.29240/tik.v8i2.9776,,,0,,0,true,cc-by-nc-sa,gold -146-720-694-365-813,Έρευνα των οικονομικών της εκπαίδευσης: Μία πολύπλευρη επισκόπηση (1993-2022),2024-09-04,2024,journal article,"Εκπαίδευση, Δια Βίου Μάθηση, Έρευνα και Τεχνολογική Ανάπτυξη, Καινοτομία και Οικονομία",25292153,National Documentation Centre (EKT),,Χρήστος Κόκκορης; Νίκος Κουτσουπιάς; Νικόλαος Βασιλειάδης,"Περίληψη; Η σύνδεση της Εκπαίδευσης και της Οικονομικής Έρευνας έχει αυξηθεί σημαντικά, επιτρέποντας συστηματικές και βιβλιομετρικές αναλύσεις. Είναι ενδιαφέρον ότι δεν έχει γίνει ακόμη βιβλιομετρική έρευνα για την μεταξύ τους σχέση (EdER). Για να καλυφθεί αυτό το κενό, η μελέτη μας χρησιμοποιεί βιβλιομετρικές τεχνικές πραγματοποιώντας μια στατιστική ανασκόπηση 4335 δημοσιευμένων μελετών και να ποσοτικοποιήσει την επίδραση τους στην επιστημονική κοινότητα, εστιάζοντας σε τρεις εξέχουσες πηγές, συγκεκριμένα: Economics of Education, International Journal of Educational Development και Οικονομικά της Εκπαίδευσης. Πραγματοποιήσαμε μια βιβλιομετρική εξέταση, ταυτοχρόνως ποιοτική και ποσοτική, χρησιμοποιώντας δημοσιεύσεις μέσω του ευρετηρίου Scopus από θέματα Οικονομικών που δημοσιεύτηκαν τις προηγούμενες τρεις δεκαετίες, καθώς και το λογισμικό ανάλυσης δεδομένων R-language bibliometrix. Η έρευνα αποκάλυψε ποικιλία αποτελεσμάτων, συμπεριλαμβανομένων πληροφοριών για τους πιο εξέχοντες συγγραφείς και περιοδικά. Διερευνήσαμε, επίσης, τα θέματα και τις τρέχουσες ερευνητικές τάσεις στον τομέα των οικονομικών της εκπαίδευσης, καθώς και την εξέλιξη των ερευνητικών ροών και τάσεων στα πεδία του EDER.; Abstract; The connection of Education and Economic Research has grown significantly, allowing for systematic and bibliometric analyses. Interestingly, no bibliometric research has yet been done on the relationship between them (EdER). To fill this gap, our study uses bibliometric techniques by conducting a statistical review of 4335 published studies and quantifying their impact on the scientific community, focusing on three prominent sources, namely: Economics of Education, International Journal of Educational Development and Economics of Education. We performed a bibliometric review, both qualitative and quantitative, using publications through the Scopus index from Finance topics published in the previous three decades, as well as the R-language bibliometrix data analysis software. The search revealed a variety of results, including information on the most prominent authors and journals. We also explored the topics and current research trends in the field of education economics, as well the evolution of research streams and trends in EDER fields.;  ;  ",3,,1,16,Business,,,,,,http://dx.doi.org/10.12681/elrie.7120,,10.12681/elrie.7120,,,0,,0,true,,bronze -146-981-598-030-47X,Research Trend of Computational Thinking in Phiysics Learning: a Bibliometric Analysis from 2015 to 2024,2025-05-28,2025,journal article,Jurnal Pendidikan Progresif,25501313; 20879849,Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Lampung,,Riskawati Riskawati; Dadi Rusdiana; Abdurrahman Abdurrahman; Hendra Hendra,"Research Trend of Computational Thinking in Phiysics Learning: a Bibliometric Analysis from 2015 to 2024. This study performs bibliometric analysis to examine research development on CT in physics education for the years spanning 2015-2024. Objective: The study seeks to outline the research and intellectual history of Computation Thinking (CT) integration within a specific framework by examining its spatial development in terms of the primary contributors CT’s development through analyzing cumulative research, leading journals, contributing countries, dominant scholars, thematic networks and the changes of key topics over time. Methods: From the Scopus database, 345 peer-reviewed journal articles were selected. To visualize research networks, VOSviewer was used, while Bibliometrix in R Studio was used to analyze publication trends, author contributions, journal impact, citations, and assess the citation patterns of work over time. Findings: From the Scopus database, a total of 345 peer-reviewed journals were selected. The quantitative data analysis involving visualization of research networks was done using VOSviewer, while Bibliometrix (R Studio) was used for evaluation of publication and author contributions in relation to impact, citation, and trends. Findings indicate significant growth in research focused on Computational Thinking (CT) in Physics Education, with an overarching 33.86% annual increase, peaking in 2023. The research covers 156 journals, with the most prolific being Education and Information Technologies. The evaluation emphasized the exceptional worldwide collaboration with 1,216 authors from countries like the United States, Indonesia, and China. Intent phrase clusters included “computational thinking”, “augmented reality”, and “STEM education” indicating an emphasis on the integration of CT with advanced technologies. The evolution of themes indicates movement from STEM simulations to more expansive virtual reality and critical thinking. Conclusions: The advancements in physics education and students' problem-solving skills, as well as teaching innovations through International collaborations, have begun using Computational Thinking CT). Keywords: computational thinking, physics education, bibliometric analysis, vosviewer, bibliometrix.",15,2,1041,1060,,,,,,,http://dx.doi.org/10.23960/jpp.v15i2.pp1041-1060,,10.23960/jpp.v15i2.pp1041-1060,,,0,,0,false,, -147-441-192-431-838,Gaps and overlaps between sustainability science and the environmental humanities,2024-12-21,2024,journal article,Sustainability Science,18624065; 18624057,Springer Science and Business Media LLC,Germany,Julien Blanco; Clémence Moreau; Stéphanie M. Carrière; Elodie Fache; Miriam Cué Rio; François Calatayud; Jean-Christophe Castella; Pierre-Yves Le Meur; Émilie Coudel; Dominique Hervé; Philippe Méral; Clara Therville,,20,2,581,596,Sustainability science; Sustainability; Discipline; Compartmentalization (fire protection); Sociology; Multidisciplinary approach; Face (sociological concept); Social science; Politics; Political science; Environmental ethics; Engineering ethics; Humanities; Social sustainability; Ecology; Engineering; Biology; Biochemistry; Law; Enzyme; Philosophy,,,,,https://hal.science/hal-04861371/document https://hal.science/hal-04861371,http://dx.doi.org/10.1007/s11625-024-01596-1,,10.1007/s11625-024-01596-1,,,0,000-555-547-088-093; 002-052-422-936-00X; 003-558-304-940-141; 003-634-382-917-205; 003-950-885-445-582; 006-490-884-992-773; 006-808-502-767-966; 007-217-784-033-056; 007-955-378-732-681; 010-442-924-794-711; 010-811-838-285-698; 011-407-276-108-72X; 012-304-253-221-732; 013-507-404-965-47X; 014-038-173-697-865; 014-386-588-042-781; 015-588-764-088-482; 018-018-024-026-176; 019-251-861-610-73X; 019-407-183-119-834; 022-050-154-142-786; 022-165-244-102-69X; 022-620-912-637-932; 027-256-606-910-324; 032-519-351-701-952; 033-648-918-097-117; 034-171-490-691-342; 034-882-424-844-954; 035-903-582-154-373; 040-905-343-969-479; 045-999-706-536-229; 047-342-148-086-791; 049-324-485-023-242; 052-106-280-351-931; 052-441-141-651-211; 052-911-575-277-478; 054-515-667-411-871; 055-877-976-999-415; 058-166-636-662-419; 061-770-751-505-469; 072-921-999-318-899; 074-911-812-225-259; 092-680-249-764-700; 093-786-426-226-498; 104-909-735-797-256; 110-451-901-063-959; 120-310-601-377-597; 121-505-620-733-717; 125-560-706-558-101; 125-844-332-172-267; 127-855-380-327-784; 134-768-556-326-40X; 134-904-403-042-290; 135-007-752-575-817; 142-951-755-290-361; 147-352-647-890-797; 148-538-015-643-183; 156-037-674-094-944; 158-863-693-774-870; 166-472-299-878-85X; 177-384-188-247-421; 183-226-267-116-319; 191-430-748-090-402,1,false,, -147-447-306-042-249,Scientific evolution from the definition of Hirschsprung disease to the present: a bibliometric analysis (1980-2023).,2025-02-20,2025,journal article,Pediatric research,15300447; 00313998,Springer Science and Business Media LLC,United States,Nurcan Çoşkun; Mehmet Metin,,,,,,Disease; Medicine; Psychology; Internal medicine,,,,,,http://dx.doi.org/10.1038/s41390-025-03927-z,39979585,10.1038/s41390-025-03927-z,,,0,001-283-122-690-273; 002-052-422-936-00X; 004-035-643-112-483; 007-642-769-575-014; 007-788-452-501-879; 008-324-787-460-272; 010-427-330-270-333; 011-373-241-150-482; 013-051-366-999-819; 013-507-404-965-47X; 014-718-870-631-078; 018-728-502-279-319; 020-688-272-660-517; 023-515-488-982-332; 024-617-700-257-140; 026-284-476-827-099; 027-632-324-568-598; 029-139-033-142-216; 032-921-506-370-736; 035-446-730-902-820; 036-580-250-330-708; 040-460-275-035-519; 042-245-752-544-481; 047-182-600-298-900; 048-145-138-353-044; 050-214-448-262-170; 052-142-183-998-82X; 063-603-452-772-73X; 064-673-411-529-872; 071-714-096-117-262; 072-498-326-485-849; 077-063-143-785-979; 081-013-370-567-137; 086-053-749-511-160; 088-743-963-978-176; 090-761-706-815-350; 091-845-520-714-652; 095-948-970-845-454; 097-070-436-393-697; 099-994-531-817-964; 101-752-490-869-458; 104-127-564-549-509; 105-577-519-402-975; 118-259-463-282-705; 119-419-450-313-599; 121-077-011-012-465; 124-992-209-822-736; 134-867-020-993-726; 138-926-163-661-57X; 144-058-743-366-665; 144-670-325-136-77X; 147-648-918-513-348; 166-289-752-932-610; 169-934-468-624-678; 174-452-492-262-127; 178-581-375-962-104; 184-390-078-171-459; 186-420-582-354-331,1,false,, -147-599-983-042-046,A Bibliometric Study on Charcot Foot Deformity.,2023-06-12,2023,journal article,The international journal of lower extremity wounds,15526941; 15347346,SAGE Publications,United States,Alaaddin Oktar Üzümcügil; Sevil Alkan; Mehmet Kurt,"In this study, we investigated the literature's publication trends related to the Charcot foot deformity. Using bibliometric analysis to examine the data of origin, this analysis was carried out by conducting an electronic search of the Web of Science database for research articles between 1970 and March 2023. We used the following search term in the search bar: TI  =  (Charcot foot OR Charcot foot deformity OR Charcot's foot OR Charcot Osteopathic Arthropathy) with English language and article-format filtering for documents. The bibliometric analysis was carried out using R's ""Bibliometrix"" package program. A total of 437 articles were found in the electronic search. A total number of 1513 authors from around the world contributed to the Charcot foot literature, with the most articles published (42.1%) originating in the United States. The United States had the highest proportion of citations (3332 citations). The highest number of articles (n = 245) on Charcot foot deformity was in the last decade. 2021 was the year with the most articles (n = 34). The authors from the United States and the United Kingdom had the highest number of international collaborations. The study offers researchers a current overview of essential data and may help direct future research by summarizing the main points and research trends on the topic of Charcot foot deformity.",,,15347346231179850,,Medicine; Foot (prosody); Bibliometrics; Deformity; Electronic database; Foot deformity; Web of science; MEDLINE; Physical therapy; Surgery; Library science; Database; Pathology; Meta-analysis; Philosophy; Linguistics; Computer science; Political science; Law,Bibliometrix®; Charcot foot; Web of Science; collaborative network; foot deformity; publication,,,,,http://dx.doi.org/10.1177/15347346231179850,37306122,10.1177/15347346231179850,,,0,011-950-293-929-372; 012-607-394-261-795; 013-507-404-965-47X; 039-668-859-096-873; 046-576-756-186-45X; 052-655-010-389-106; 058-572-302-082-215; 078-730-658-883-108; 090-608-642-258-311; 092-993-102-056-424; 103-144-657-851-430; 109-739-243-456-976; 122-822-540-493-050; 123-648-657-208-706; 126-953-365-707-327; 138-311-484-672-455; 185-556-111-167-851,5,false,, -147-850-871-887-842,Artificial intelligence alphafold model for molecular biology and drug discovery: a machine-learning-driven informatics investigation.,2024-10-05,2024,journal article,Molecular cancer,14764598,Springer Science and Business Media LLC,United Kingdom,Song-Bin Guo; Yuan Meng; Liteng Lin; Zhen-Zhong Zhou; Hai-Long Li; Xiao-Peng Tian; Wei-Juan Huang,"AlphaFold model has reshaped biological research. However, vast unstructured data in the entire AlphaFold field requires further analysis to fully understand the current research landscape and guide future exploration. Thus, this scientometric analysis aimed to identify critical research clusters, track emerging trends, and highlight underexplored areas in this field by utilizing machine-learning-driven informatics methods. Quantitative statistical analysis reveals that the AlphaFold field is enjoying an astonishing development trend (Annual Growth Rate = 180.13%) and global collaboration (International Co-authorship = 33.33%). Unsupervised clustering algorithm, time series tracking, and global impact assessment point out that Cluster 3 (Artificial Intelligence-Powered Advancements in AlphaFold for Structural Biology) has the greatest influence (Average Citation = 48.36 ± 184.98). Additionally, regression curve and hotspot burst analysis highlight ""structure prediction"" (s = 12.40, R2 = 0.9480, p = 0.0051), ""artificial intelligence"" (s = 5.00, R2 = 0.8096, p = 0.0375), ""drug discovery"" (s = 1.90, R2 = 0.7987, p = 0.0409), and ""molecular dynamics"" (s = 2.40, R2 = 0.8000, p = 0.0405) as core hotspots driving the research frontier. More importantly, the Walktrap algorithm further reveals that ""structure prediction, artificial intelligence, molecular dynamics"" (Relevance Percentage[RP] = 100%, Development Percentage[DP] = 25.0%), ""sars-cov-2, covid-19, vaccine design"" (RP = 97.8%, DP = 37.5%), and ""homology modeling, virtual screening, membrane protein"" (RP = 89.9%, DP = 26.1%) are closely intertwined with the AlphaFold model but remain underexplored, which implies a broad exploration space. In conclusion, through the machine-learning-driven informatics methods, this scientometric analysis offers an objective and comprehensive overview of global AlphaFold research, identifying critical research clusters and hotspots while prospectively pointing out underexplored critical areas.",23,1,223,,Drug discovery; Biology; Informatics; Computational biology; Artificial intelligence; Data science; Machine learning; Bioinformatics; Computer science; Electrical engineering; Engineering,AlphaFold; Artificial intelligence; Bibliometrics; Drug discovery; Molecular dynamics; Structure prediction,Machine Learning; Drug Discovery/methods; Humans; Artificial Intelligence; COVID-19/virology; SARS-CoV-2; Algorithms; Computational Biology/methods; Molecular Biology,,National Natural Science Foundation of China (82422010); Guangdong Basic and Applied Basic Research Foundation (2024B1515020026),,http://dx.doi.org/10.1186/s12943-024-02140-6,39369244,10.1186/s12943-024-02140-6,,PMC11452995,0,002-756-144-887-214; 011-301-822-302-672; 012-348-107-291-446; 013-507-404-965-47X; 023-690-891-794-778; 026-652-481-708-867; 029-230-775-505-212; 045-038-629-466-526; 046-992-864-415-70X; 090-126-288-158-542; 093-546-902-873-280; 103-212-983-826-945; 107-297-067-081-184; 125-166-906-573-968; 151-885-746-080-745; 156-384-098-893-807; 173-312-059-754-277; 193-662-520-624-32X,34,true,"CC BY, CC0",gold -148-174-371-633-93X,A bibliometric and systematic review of scientific publications on metaverse research in architecture: web of science (WoS),2024-07-02,2024,journal article,International Journal of Technology and Design Education,09577572; 15731804,Springer Science and Business Media LLC,Netherlands,Güneş Mutlu Avinç; Aslı Yıldız,"Abstract; The global trends related to the concept of Metaverse in architecture have significantly expanded in recent years, thanks to the increasing number of scientific publications. Systematically examining the literature on this topic and identifying research trends and potential directions provides comprehensive data maps, thus charting a roadmap for researchers interested in working in this field. In this context, the research aims to identify the trends and tendencies of the concept of the Metaverse in the scientific literature over time at the primary analysis levels, such as countries, institutions, resources, articles, authors, and research topics. The research conducted with this aim involves a dynamic, visual, and systematic examination of the academic literature on academic publishing using data accessed without year limitations from the Web of Science Core Collection-Citation database. In the research conducted without year limitations, a sample comprising 334 articles published/planned to be published between 2005 and 2024 is analyzed. The bibliometrix R-Tool was used to enhance the analysis, and metadata was obtained from the WoS database. This analysis analyzed publications, citations, and information sources, including the most published journals, the most used keywords, the most cited and leading articles, the most cited academics, and the most contributing institutions and countries. In conclusion, this study aims to define the profile of international academic publishing in the field of the Metaverse, present its development, identify research fronts, detect emerging trends, and uncover the working themes and trends in the Metaverse specific to architecture. This study describes the profile of international academic publishing on the metaverse, presents its development, identifies research frontiers, identifies emerging trends, and reveals metaverse study themes and trends in architecture. As a result, education, virtual perception of space, building operation and maintenance, building evacuation, BIM (Building Information Modeling), cultural heritage, physical environment, built environment/planning, smart home, design and creativity, universal design/accessibility, sustainability, smart city/GIS, urban transportation systems, and in-use evaluation are identified as themes that have been studied in relation to the metaverse concept in architecture and design disciplines.",35,2,825,849,Publishing; Context (archaeology); Metadata; Metaverse; Data science; Citation; Computer science; Field (mathematics); Web of science; Scientific literature; Citation analysis; World Wide Web; Library science; Political science; Geography; MEDLINE; Virtual reality; Archaeology; Paleontology; Mathematics; Artificial intelligence; Pure mathematics; Law; Biology,,,,Mus Alparslan University,https://link.springer.com/content/pdf/10.1007/s10798-024-09918-1.pdf https://doi.org/10.1007/s10798-024-09918-1,http://dx.doi.org/10.1007/s10798-024-09918-1,,10.1007/s10798-024-09918-1,,,0,000-413-690-580-538; 000-457-222-570-499; 001-719-026-803-199; 002-052-422-936-00X; 005-391-955-716-830; 009-924-638-362-180; 012-166-047-635-851; 013-192-874-281-79X; 013-507-404-965-47X; 013-873-936-137-800; 014-967-624-802-326; 015-224-891-008-812; 018-503-822-451-854; 019-819-261-965-237; 020-176-944-299-121; 022-813-153-687-20X; 023-826-233-397-949; 026-979-861-470-20X; 027-406-540-345-844; 029-672-908-532-520; 031-378-521-348-344; 033-894-460-189-370; 035-420-787-193-652; 035-953-579-141-278; 037-381-042-004-785; 041-203-752-304-902; 042-572-968-622-862; 044-615-478-811-601; 046-096-656-702-960; 046-893-786-173-907; 047-526-001-775-02X; 049-262-053-470-144; 052-148-901-274-728; 053-288-006-197-640; 055-524-941-131-76X; 055-794-301-204-246; 061-286-166-314-990; 062-875-828-131-432; 064-368-092-113-325; 064-674-585-297-201; 066-043-814-551-050; 066-574-574-975-032; 067-931-331-309-27X; 069-075-843-958-111; 069-944-576-835-513; 071-834-558-305-919; 073-839-550-648-410; 074-689-637-760-304; 077-218-436-623-723; 077-220-267-493-915; 078-815-997-126-120; 078-981-179-378-311; 092-095-036-308-077; 095-984-923-158-051; 100-197-628-193-512; 102-617-832-200-848; 105-729-843-857-437; 106-087-044-235-054; 107-867-093-425-042; 110-198-347-254-283; 112-524-198-294-495; 113-324-298-927-667; 114-517-135-252-252; 117-266-252-867-454; 120-353-842-716-385; 120-885-678-404-810; 123-105-100-800-015; 123-202-581-406-928; 125-223-924-466-523; 126-016-643-768-255; 128-170-655-591-15X; 129-173-414-558-340; 131-304-978-502-00X; 131-327-339-368-598; 132-223-377-723-722; 136-033-631-859-747; 138-772-017-154-183; 138-934-095-706-878; 143-960-381-071-893; 145-641-669-106-025; 146-740-792-602-681; 150-441-109-203-091; 151-083-733-236-304; 151-206-906-004-067; 151-989-472-192-024; 154-960-782-965-408; 166-312-300-947-160; 167-559-921-757-387; 169-442-230-869-770; 169-457-906-799-250; 171-876-340-007-637; 175-364-413-914-585; 177-778-631-705-151; 178-022-755-676-512; 178-051-586-237-457; 179-459-550-536-258; 180-637-138-719-997; 182-242-355-047-118; 184-141-568-948-93X; 185-951-122-491-569; 187-536-279-881-332; 193-017-756-455-436; 193-944-704-251-316; 195-090-000-351-155; 197-286-131-011-043; 197-549-797-962-138; 199-818-015-201-285,4,true,cc-by,hybrid -148-778-294-324-849,Resilience-based Governance: A Public Administration Perspective and Resilience Agenda,2025-03-08,2025,journal article,Public Organization Review,15667170; 15737098,Springer Science and Business Media LLC,Netherlands,Abdillah Abdillah; Ida Widianingsih; Rd Ahmad Buchari; Heru Nurasa,,,,,,Resilience (materials science); Public finance; Perspective (graphical); Corporate governance; Political science; Public administration; Administration (probate law); Sociology; Business; Finance; Computer science; Physics; Artificial intelligence; Law; Thermodynamics,,,,,,http://dx.doi.org/10.1007/s11115-025-00834-z,,10.1007/s11115-025-00834-z,,,0,000-057-280-251-602; 002-052-422-936-00X; 005-973-159-379-597; 009-707-869-544-052; 014-439-864-649-421; 018-886-284-627-138; 019-199-601-266-797; 020-745-957-863-446; 021-229-318-470-086; 037-800-690-031-849; 040-822-765-273-62X; 041-179-209-119-767; 041-402-845-487-500; 042-166-159-994-750; 046-383-797-737-43X; 046-456-346-673-742; 049-391-379-302-694; 049-701-623-045-783; 049-704-668-831-888; 050-967-631-044-127; 051-576-792-334-713; 051-649-510-064-001; 054-863-060-504-562; 056-220-225-677-968; 065-010-405-236-060; 065-351-023-139-906; 065-444-912-539-013; 071-149-112-308-327; 072-907-448-548-267; 074-243-010-556-055; 075-041-199-126-93X; 075-296-952-421-707; 075-448-624-213-490; 075-822-782-578-257; 076-255-685-327-235; 076-798-007-807-978; 078-952-049-838-866; 079-602-629-672-467; 091-109-494-476-463; 091-379-554-408-818; 094-178-030-158-385; 095-698-535-348-526; 100-924-070-002-251; 101-286-065-404-574; 102-830-011-481-649; 102-887-599-296-408; 104-463-933-101-965; 112-826-723-331-770; 119-788-177-010-098; 122-825-868-492-936; 124-071-886-776-662; 124-312-042-212-044; 128-446-462-302-774; 132-616-431-723-983; 136-723-532-094-185; 146-106-325-667-39X; 150-096-525-967-627; 150-676-980-672-055; 151-343-391-301-53X; 166-472-299-878-85X; 174-527-434-531-273; 182-209-011-149-482; 195-971-174-123-769,2,false,, -148-902-151-286-668,thesaurus-bib-delete.txt,2023-01-01,2023,dataset,Figshare,,,,Gaimei She,"""thesaurus-bib-delete.txt"": Meaningless keywords elimination file applied in Bibliometrix software. VOSviewer v1.6.18.0 and Bibliometricx were used to perform the analyses of the collected documents. This file was used in Bibliometricx software.",,,,,Thesaurus; Information retrieval; Computer science; Natural language processing; Artificial intelligence,,,,,https://figshare.com/articles/dataset/thesaurus-bib-delete_txt/21875337,http://dx.doi.org/10.6084/m9.figshare.21875337,,10.6084/m9.figshare.21875337,,,0,,0,true,cc-by,gold -148-946-291-158-427,Bibliometric and visual analysis of circadian rhythms in depression from 2004 to 2024.,2025-05-14,2025,journal article,Annals of general psychiatry,1744859x,Springer Science and Business Media LLC,United Kingdom,Cong Zhou; Shanling Ji; Aoxue Zhang; Hao Yu; Chuanxin Liu; Sen Li,"Understanding the intricate relationship between circadian rhythms and depression is crucial for developing effective interventions and treatments for individuals affected by depression. Circadian rhythms regulate various physiological and behavioral processes, while depression manifests as persistent feelings of sadness and disturbances in sleep, appetite, and energy levels. Emerging research suggests a significant interplay between circadian rhythm disruption and depression, highlighting the need for comprehensive analysis in this area.; A bibliometric and visual analysis of literature on circadian rhythms in depression from 2004 to 2024 was conducted using the Web of Science Core Collection. Data were analyzed using bibliometric tools including VOSviewer, CiteSpace, and Bibliometrix to identify publication trends, geographical distribution, authorship patterns, institutional collaborations, journal preferences, keyword co-occurrence, and highly cited references.; Analysis revealed a steady increase in publications and citations related to circadian rhythms in depression. The United States emerged as the leading contributor, with strong global collaborations. Key journals included Chronobiology International and Journal of Affective Disorders. Top keywords included circadian rhythm, depression, sleep, melatonin, and bipolar disorder. The most cited article is a review titled ""Practice parameters for the indications for polysomnography and related procedures: An update for 2005"".; This study offers a comprehensive overview of research on circadian rhythms in depression, highlighting key trends, contributors, and interdisciplinary intersections.; © 2025. The Author(s).",24,1,27,,Geriatric psychiatry; Circadian rhythm; Depression (economics); Psychopharmacology; Forensic psychiatry; Psychiatry; Medicine; Neuroscience; Psychology; Economics; Macroeconomics,Bibliometric; Circadian rhythms; Depression; Visualize,,,"Medical and Health Science and Technology Development Plan of Shandong Province (202304011343); Ministry of Education Industry-University Cooperative Education Project (220900242232529); Key Research and Development Plan of Jining City (2021YXNS024, 2021YXNS127); the Cultivation Plan of High-level Scientific Research Projects of Jining Medical University (JYGC2021KJ006)",,http://dx.doi.org/10.1186/s12991-025-00565-x,40369622,10.1186/s12991-025-00565-x,,PMC12080064,0,002-052-422-936-00X; 002-163-636-269-339; 003-341-327-857-941; 007-142-618-722-143; 009-176-596-873-87X; 011-496-077-033-371; 013-507-404-965-47X; 013-607-096-801-323; 014-221-364-799-325; 019-737-077-537-508; 020-243-404-292-129; 029-271-527-804-230; 030-488-818-261-996; 031-523-397-355-19X; 032-470-918-915-026; 034-494-726-011-902; 035-940-723-319-403; 036-656-168-693-890; 036-871-634-296-06X; 037-175-875-566-523; 040-356-156-781-682; 042-515-532-948-369; 042-561-879-813-655; 052-116-754-833-254; 053-038-743-933-650; 054-974-407-318-278; 061-075-009-028-886; 069-899-635-985-280; 090-130-845-759-132; 121-676-473-336-231; 123-226-014-846-763; 124-129-352-566-483; 124-140-839-245-048; 139-165-653-086-515; 143-688-847-765-126; 151-413-735-572-896; 151-444-335-747-994; 157-986-943-763-597; 160-643-329-362-535; 162-607-505-976-62X; 166-231-300-324-161,0,true,"CC BY, CC0",gold -149-130-685-842-517,Mapping the Research Trends on Dark Tourism: A Bibliometric Analysis and Visualization,2023-11-10,2023,journal article,Acta Universitatis Bohemiae Meridionalis,12123285; 23364297,University of South Bohemia in Ceske Budejovice,,Biswabhusan Pradhan; Manjeet Singh; Asit Mantry; Engy El-Kilany; Manju Shree Raman; Archana Bhatia,"Bibliometrics is a tool that enables the analysis of historical development, present conditions, and prospective trends in a specific field of study. The purpose of this research is to examine dark tourism research that was published between 2007 and 2021. A total of 234 important publications were systematically retrieved and bibliometrically analyzed from the Scopus database. To examine and illustrate the dark tourism research trend, the current study used the Bibliometrix tool. To represent the general pattern and structure of dark tourism research, the final analysis incorporates bibliometric indicators such as annual scientific production, most prolific journal, most prolific author, country and institutions, most impactful articles, co-citation and author's keywords. The finding of this analysis shows that publications on dark tourism have expanded dramatically and are dominated by a small number of writers and nations. The study provides theoretical and practical insight into dark tourism research.",26,2,1,17,Visualization; Tourism; Data science; Computer science; Regional science; Geography; Data mining; Archaeology,,,,,http://acta.ef.jcu.cz/doi/10.32725/acta.2023.005.pdf https://doi.org/10.32725/acta.2023.005,http://dx.doi.org/10.32725/acta.2023.005,,10.32725/acta.2023.005,,,0,000-930-868-404-394; 004-251-288-485-221; 005-671-501-635-688; 007-385-654-303-292; 013-507-404-965-47X; 014-900-492-906-687; 015-808-062-103-002; 016-655-706-124-813; 021-358-544-070-305; 025-855-318-734-145; 026-634-199-389-074; 027-175-993-272-216; 032-318-770-533-876; 032-983-548-285-955; 033-281-398-001-821; 034-536-843-797-265; 038-735-788-688-96X; 041-468-168-170-89X; 044-443-033-750-115; 046-479-840-984-847; 046-992-864-415-70X; 047-510-743-617-358; 051-575-571-916-045; 053-475-466-263-788; 054-738-940-947-721; 058-916-790-987-959; 058-970-275-494-25X; 063-205-441-419-11X; 066-141-147-725-908; 069-372-492-194-439; 069-878-089-213-693; 074-221-610-053-737; 080-384-934-710-127; 089-460-913-426-732; 095-496-704-840-429; 106-880-509-994-485; 109-045-137-086-901; 115-331-152-380-601; 119-224-661-604-660; 125-999-873-577-714; 126-932-978-554-543; 129-010-056-342-622; 140-775-683-520-945; 142-497-784-429-388; 147-700-773-981-786; 155-451-505-696-597; 156-681-449-846-385; 156-749-933-596-566; 173-504-571-067-261; 185-376-567-976-042; 187-703-070-908-528,3,true,cc-by,hybrid -149-410-954-961-554,Invisible borders in educational technology research? A comparative analysis.,2023-02-07,2023,journal article,Educational technology research and development : ETR & D,10421629; 15566501,Springer Boston,United States,Victoria I Marín; Katja Buntins; Svenja Bedenlier; Melissa Bond,"Educational research is reflective of the nature and structure of national and regional education systems and their historical evolution. Educational technology research, as an area within educational research, reflects this case particularly prominently. Although individual countries and regions have varying research traditions, the publication of research in English as the scientific lingua franca can lead to missing nuances in terminology, which is often not reflected upon. Despite this, the exploration of research from different countries can still uncover diverse topical clusters. This study aims to identify the research topics in educational technology research in three countries (Germany, Spain and the United Kingdom), each with their own research traditions, through the terms used. To this end, a bibliometric analysis of 3034 article abstracts and keywords from 29 English-language Web of Science journals in the field of education and educational research was conducted, with a focus on educational technology. In addition, the quantitative findings are comparatively analysed by considering the corresponding cultural clusters. Main findings include diverse research foci in the three countries, also showing that distinct research traditions are still present, despite using English as lingua franca. Therefore, research articles written in English by non-English authors often do not reflect the same meanings in each country, despite using the same words. The conclusions reflect upon the need to establish ways of understanding the traditions behind those research articles and build collaborative systems to illustrate nuances in this research.",,,1,,Terminology; Educational research; Lingua franca; Sociology; Educational technology; Pedagogy; Linguistics; Philosophy,Bibliometric analysis; Comparative research; Educational research traditions; Educational technology research,,,Ministerio de Ciencia e Innovación; European Social Fund; Universitat de Lleida,https://link.springer.com/content/pdf/10.1007/s11423-023-10195-3.pdf https://doi.org/10.1007/s11423-023-10195-3 https://repositori.udl.cat/bitstream/10459.1/85374/1/033035.pdf http://hdl.handle.net/10459.1/85374 https://discovery.ucl.ac.uk/10171812/1/s11423-023-10195-3.pdf https://discovery.ucl.ac.uk/id/eprint/10171812/ https://discovery.ucl.ac.uk/id/eprint/10171812/1/s11423-023-10195-3.pdf,http://dx.doi.org/10.1007/s11423-023-10195-3,36779077,10.1007/s11423-023-10195-3,,PMC9904257,0,002-409-140-565-633; 003-069-271-104-982; 005-650-400-596-170; 007-776-800-233-252; 008-573-685-534-696; 012-532-551-115-377; 013-507-404-965-47X; 015-388-090-510-686; 019-614-030-091-983; 023-313-417-894-268; 028-383-940-982-663; 033-945-897-277-258; 038-308-829-764-214; 048-085-584-981-76X; 051-298-295-108-777; 054-976-839-876-889; 060-672-397-552-039; 064-610-099-860-086; 071-403-564-644-381; 074-976-378-557-521; 075-347-136-339-593; 082-905-537-522-863; 083-572-259-273-820; 098-659-046-832-533; 108-460-211-252-560; 119-557-426-467-219; 121-086-662-316-416; 123-446-482-013-396; 132-478-088-570-365; 154-717-160-606-259; 155-418-313-734-830; 160-764-618-500-106; 161-100-932-716-84X; 162-033-710-800-244; 165-472-873-302-69X; 177-328-250-035-387,8,true,cc-by,hybrid -149-503-960-883-647,Decoding the future: a bibliometric exploration of blockchain in logistics,2025-01-12,2025,journal article,Financial Innovation,21994730,Springer Science and Business Media LLC,,Mª Del Valle Fernández Moreno; Juan Miguel Alcántara-Pilar; Marta Tolentino,"Abstract; This paper presents the results of a bibliometric analysis concerning the application of blockchain technology to logistics. It aims to discern the relational structure among past and current topics, predict emerging trends, and provide a longitudinal perspective on this research domain. Using co-word analysis techniques, we employ SciMAT software to analyze over 800 papers from 2016 to March 2023. The investigation enhances the understanding of blockchain technology, revealing that scientific production in this area revolves around eight primary thematic clusters. Visual representations of the results are provided through longitudinal maps and strategic diagrams, illustrating pivotal themes across the three study periods: blockchain and sustainability. Smart contracts emerge as a focal topic in the final period under consideration.",11,1,,,Blockchain; Decoding methods; Computer science; Parallel computing; Algorithm; Computer security,,,,Ministerio de Ciencia e Innovación; Ministerio de Ciencia e Innovación; Junta de Comunidades de Castilla-La Mancha; Junta de Comunidades de Castilla-La Mancha,,http://dx.doi.org/10.1186/s40854-024-00736-x,,10.1186/s40854-024-00736-x,,,0,001-223-177-378-370; 005-127-277-107-725; 005-277-610-241-914; 006-912-721-410-174; 007-589-589-399-930; 010-474-184-242-896; 011-482-239-403-586; 012-132-843-708-649; 012-162-081-192-515; 013-150-741-470-292; 013-647-345-912-857; 026-185-556-134-379; 032-328-271-181-991; 038-631-624-874-022; 040-838-688-716-533; 040-928-760-339-517; 041-272-295-929-825; 042-314-004-394-517; 042-394-228-997-686; 043-155-133-045-314; 046-053-754-239-842; 046-221-256-075-961; 049-162-815-899-249; 049-285-500-063-383; 049-915-511-575-054; 050-191-879-559-444; 050-568-549-317-140; 050-893-374-534-416; 051-266-797-600-087; 055-694-149-090-820; 057-003-191-823-175; 057-942-097-777-139; 062-107-634-706-54X; 063-261-496-298-024; 064-965-499-181-544; 066-287-905-980-759; 070-372-317-975-831; 078-542-170-294-248; 079-388-097-137-118; 080-497-361-174-582; 081-607-243-602-76X; 082-025-968-765-351; 089-409-767-761-917; 091-675-281-904-766; 095-200-155-897-688; 097-759-335-124-834; 105-089-966-614-539; 105-280-329-717-303; 108-398-190-639-373; 111-488-095-711-880; 113-776-567-679-25X; 121-673-786-804-573; 125-917-485-906-289; 132-321-083-880-844; 134-151-947-852-116; 142-542-589-206-146; 149-322-612-082-39X; 152-922-114-288-392; 153-993-151-696-648; 158-020-983-863-972; 159-392-490-913-656; 171-115-818-447-150; 187-703-070-908-528; 189-725-779-776-737,2,true,cc-by,gold -149-783-661-115-364,Geoheritage Research Trends: A Comparative Bibliometric Analysis of Global and Türkiye Perspectives Using R Programming,2025-04-30,2025,journal article,Geoheritage,18672477; 18672485,Springer Science and Business Media LLC,Germany,Yaren Göktaş; Zeki Boyraz,"Abstract; Geoheritage refers to the scientific, aesthetic and cultural value of geological formations and is closely related to the concepts of geotourism, geosite, geopark, geodiversity and geoconservation. All these concepts work together to protect the scientific, educational and economic value of geoheritage and to use it sustainably. In this study, the findings of a bibliometric analysis that comparatively examines geoheritage literature in the international and Turkish context are presented. The analysis was carried out using the Biblioshiny package of the R program. The methodology of the study is as follows: determining the boundaries of the research, collecting data, analyzing data, creating and interpreting bibliometric maps. In the first stage of the research, studies conducted between 1994–2024 were determined using the databases Web of Science, Scopus, Google Scholar, Researcgate, Dergipark Academic, YökTez. The studies were analyzed within certain limitations and the results were visualized with bibliometric maps. The results indicate that the topic of geoheritage is explored through an interdisciplinary approach in the international literature, while the literature in Türkiye remains underdeveloped in this field at the global level. Despite the geological and geomorphological advantages provided by its geographical location, Türkiye has not been able to fully utilize its existing geoheritage potential. Establishing stronger connections between studies conducted in Türkiye and the international literature is of great importance.",17,2,,,Biogeosciences; Historical geology; Regional science; Geography; Library science; Data science; Computer science; Geology; Earth science,,,,Inonu University,,http://dx.doi.org/10.1007/s12371-025-01107-3,,10.1007/s12371-025-01107-3,,,0,004-132-856-568-69X; 006-028-123-655-852; 006-774-417-483-966; 008-255-369-558-668; 008-531-254-617-275; 009-014-606-835-243; 009-888-150-169-672; 009-889-598-122-623; 010-830-734-182-241; 012-817-651-735-652; 013-349-266-636-377; 013-507-404-965-47X; 015-737-676-310-908; 016-655-706-124-813; 016-877-624-723-162; 017-750-600-412-958; 020-268-716-115-501; 027-091-325-742-093; 030-208-658-541-825; 033-842-221-955-694; 045-833-192-880-574; 046-992-864-415-70X; 047-006-401-254-347; 049-430-889-351-663; 053-600-861-504-000; 056-255-416-548-376; 062-575-455-887-477; 063-911-136-350-142; 070-932-040-627-027; 076-307-009-187-689; 077-614-033-270-868; 081-406-752-524-770; 082-454-649-721-592; 082-915-042-584-017; 095-638-873-989-786; 096-907-717-158-402; 098-325-142-432-281; 105-911-845-873-028; 118-841-769-243-788; 121-320-585-110-520; 129-000-630-309-749; 129-590-764-047-679; 134-464-945-370-831; 143-384-700-921-806; 144-716-891-197-447; 147-233-024-439-455; 152-127-890-889-569; 167-418-025-837-080; 176-470-949-922-140,0,true,cc-by,hybrid -149-895-023-152-108,Bioeconomía. Una revisión y análisis sistemáticos desde la bibliometría,2022-07-01,2022,journal article,Revista En-contexto,27110044; 23463279,Tecnologico de Antioquia Institucion Universitaria,,Martha del Socorro Alzate Cárdenas; María Isabel Guerrero Molina; Valentina Gonzales Garcés,"El objetivo es realizar una revisión y análisis sistemático de las publicaciones realizadas sobre la bioeconomía. La metodología utilizada fue a través de bases de datos de WoS y Scopus en un periodo entre 2005- 2021, las herramientas de análisis utilizadas fueron: Bibliometrix, análisis de redes sociales, mapa de cocitaciones con revisión de documentos más relevantes y el instrumento fue Ghepi. Los resultados sugieren que la prospectiva en términos de agenda para investigación en Bioeconomía, se orienta hacia la biorefinería y procesos de transformación de residuos para una industria sostenible, la migración hacia un mundo bioeconómico y bioenergías sostenibles. ",10,17,,,Humanities; Political science; Philosophy,,,,,https://ojs.tdea.edu.co/index.php/encontexto/article/download/1246/1580 https://doi.org/10.53995/23463279.1246,http://dx.doi.org/10.53995/23463279.1246,,10.53995/23463279.1246,,,0,000-848-264-004-813; 001-475-520-664-296; 002-107-711-192-487; 002-352-077-573-619; 003-283-624-593-126; 003-440-049-745-889; 003-573-341-166-744; 004-853-700-961-591; 007-046-243-977-165; 007-050-619-972-672; 008-295-284-953-198; 008-704-777-905-412; 008-706-465-616-629; 008-956-973-527-421; 010-442-924-794-711; 011-249-559-234-645; 011-889-050-913-341; 013-291-223-931-430; 013-507-404-965-47X; 014-598-534-449-222; 015-692-170-714-052; 018-240-551-928-574; 020-345-031-753-320; 022-050-154-142-786; 025-607-351-140-661; 026-101-973-894-167; 026-288-400-313-356; 026-591-134-281-735; 026-751-007-974-782; 028-166-182-081-848; 029-696-356-795-74X; 030-383-591-112-994; 030-443-979-147-407; 031-736-198-982-587; 032-634-191-515-600; 035-897-086-767-404; 037-158-542-776-333; 037-219-124-489-784; 038-500-684-336-162; 043-478-537-347-972; 043-993-580-694-60X; 044-165-459-344-811; 044-268-817-565-721; 045-475-541-075-550; 045-643-900-040-510; 046-037-799-809-773; 047-375-589-685-555; 047-456-794-066-125; 048-878-823-324-960; 049-188-438-875-465; 049-445-490-812-589; 051-299-831-833-37X; 053-195-536-333-811; 053-598-695-896-482; 054-818-565-070-154; 057-203-608-266-48X; 057-803-697-074-453; 061-572-730-678-46X; 061-829-988-617-171; 064-086-760-311-015; 064-132-347-161-281; 064-817-435-185-090; 065-221-051-531-408; 066-400-343-948-766; 067-010-064-428-488; 067-040-123-935-744; 067-674-563-901-956; 067-975-723-728-662; 070-464-877-082-116; 074-916-635-501-939; 075-086-490-026-319; 075-611-088-489-115; 076-004-069-477-76X; 076-649-034-079-516; 076-763-426-026-244; 077-446-102-740-449; 092-416-936-225-669; 093-284-314-319-382; 094-682-881-210-156; 096-063-049-146-90X; 096-188-644-760-129; 098-129-801-227-241; 102-068-995-822-669; 104-495-326-573-684; 108-201-041-749-702; 117-297-787-561-322; 118-419-501-591-315; 119-557-426-467-219; 119-717-834-806-603; 120-287-754-465-923; 120-975-417-040-341; 127-372-688-686-63X; 130-292-429-281-599; 131-051-570-289-695; 133-610-457-080-401; 133-710-328-408-579; 137-949-827-249-98X; 139-988-878-772-871; 140-520-976-523-520; 149-449-384-202-908; 151-082-890-683-306; 156-208-441-443-940; 159-592-129-993-014; 164-595-154-568-911; 168-045-916-782-80X; 173-070-088-985-892; 188-332-136-393-173,2,true,cc-by-nc-sa,hybrid -150-052-680-955-728,A bibliometric analysis of the role of nanotechnology in dark fermentative biohydrogen production.,2024-03-26,2024,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Fakiha Tul Jannat; Kiran Aftab; Umme Kalsoom; Muhammad Ali Baig,,31,17,24815,24835,Biohydrogen; Dark fermentation; Nanotechnology; Bibliometrics; Fermentative hydrogen production; Web of science; Production (economics); Hydrogen production; Biochemical engineering; Computer science; Environmental science; Data science; Engineering; Materials science; Chemistry; Data mining; Hydrogen; MEDLINE; Macroeconomics; Organic chemistry; Economics; Biochemistry,Acidogenic fermentation; Bioenergy; Carbon footprint; Circular bioeconomy; Green chemistry; Immobilization; Renewable resources; Sustainability,Fermentation; Hydrogen/analysis; Nanotechnology; Biofuels,Hydrogen; Biofuels,,,http://dx.doi.org/10.1007/s11356-024-33005-6,38530525,10.1007/s11356-024-33005-6,,,0,000-836-595-167-512; 002-052-422-936-00X; 003-039-936-002-693; 003-304-361-686-709; 004-484-433-256-503; 006-296-616-080-162; 007-127-441-345-753; 009-022-872-773-065; 009-312-085-474-264; 012-010-247-328-118; 012-290-735-346-912; 012-403-432-427-676; 013-507-404-965-47X; 013-804-247-172-716; 016-341-744-831-349; 019-641-580-320-959; 019-764-117-584-856; 021-158-482-397-591; 022-365-858-938-623; 023-092-854-556-631; 023-217-594-036-619; 026-064-804-131-441; 029-619-661-150-383; 030-980-458-891-023; 033-065-345-060-354; 036-822-106-949-353; 037-799-243-670-707; 048-370-911-187-92X; 050-400-769-948-789; 051-319-929-095-147; 053-413-126-894-723; 059-727-558-830-109; 060-141-967-919-793; 061-405-442-194-497; 061-452-352-424-676; 065-878-164-339-03X; 068-858-842-967-416; 071-143-581-213-42X; 071-291-081-755-737; 074-814-011-272-480; 076-686-939-221-356; 078-386-512-702-036; 079-909-947-680-004; 087-724-990-241-655; 089-132-784-610-652; 091-149-003-946-181; 094-134-136-410-88X; 094-893-823-169-781; 095-101-819-806-23X; 098-066-744-644-341; 098-719-708-581-238; 098-927-476-488-136; 103-105-158-604-759; 103-727-025-660-294; 108-723-038-973-517; 112-038-743-594-853; 116-636-037-669-69X; 117-840-733-227-128; 122-990-235-973-552; 131-639-555-577-629; 133-757-847-159-63X; 136-769-212-676-614; 141-470-298-994-932; 141-641-805-814-953; 145-423-516-804-484; 147-034-908-111-429; 147-753-094-843-807; 152-540-797-380-353; 158-000-484-400-844; 166-884-028-299-646; 174-417-392-278-283; 175-429-461-075-08X; 180-051-528-329-742; 180-129-139-591-461; 184-673-596-842-507; 191-817-542-673-705,7,false,, -150-151-216-440-249,Future trends in Red Tourism and communist heritage tourism,2023-10-03,2023,journal article,Asia Pacific Journal of Tourism Research,10941665; 17416507,Informa UK Limited,United Kingdom,Víctor Calderón-Fajardo,"This paper conducts a thorough, systematic review of literature on Red or communist tourism in China, exploring its development, key drivers, impacts, and management strategies. Utilizing the PRISMA framework for unbiased and rigorous analysis, and employing Bibliometrix software for enhanced thematic and trend identification, the study maps out major themes and gaps, proposing directions for future research. The analysis reveals a predominant focus on China within the existing literature, highlighting limitations in geographical scope, tourist demographics, and academic disciplines. It also emphasizes the importance of establishing partnerships and involving local communities for effective management and promotion of Red Tourism.",28,10,1185,1198,Tourism; Scope (computer science); Promotion (chess); China; Tourism geography; Thematic analysis; Demographics; Identification (biology); Marketing; Regional science; Political science; Public relations; Business; Sociology; Qualitative research; Social science; Computer science; Botany; Demography; Politics; Law; Biology; Programming language,,,,,,http://dx.doi.org/10.1080/10941665.2023.2289415,,10.1080/10941665.2023.2289415,,,0,002-231-458-764-274; 007-370-046-587-381; 008-995-700-430-108; 010-760-639-605-882; 011-071-337-623-412; 013-541-969-076-695; 014-181-498-740-130; 015-776-163-257-816; 016-113-618-336-617; 017-635-877-223-136; 018-763-011-666-676; 018-900-628-328-595; 022-452-056-842-588; 022-995-534-570-726; 023-399-989-360-86X; 027-662-019-106-597; 028-615-902-090-576; 029-281-095-047-801; 034-075-222-741-569; 036-831-205-093-065; 037-550-015-414-716; 038-053-540-457-932; 038-445-816-547-844; 039-883-376-836-349; 040-194-594-020-438; 041-980-056-234-345; 046-272-160-744-200; 049-449-720-574-917; 059-890-005-399-072; 060-620-071-610-61X; 061-508-609-567-067; 062-295-377-546-987; 068-140-347-250-917; 068-518-401-360-087; 070-088-929-779-382; 075-158-056-476-51X; 084-858-742-125-107; 086-172-280-502-612; 102-904-285-947-767; 108-446-103-928-497; 111-660-622-470-196; 113-719-751-300-624; 115-184-599-059-956; 127-245-670-262-773; 128-340-108-092-406; 144-040-131-023-463; 144-296-093-120-412; 151-097-381-572-749; 165-611-579-372-627; 166-298-280-979-561; 166-837-328-041-303,5,false,, -150-300-265-385-238,Bibliometric mapping techniques in educational technology research: A systematic literature review,2023-09-07,2023,journal article,Education and Information Technologies,13602357; 15737608,Springer Science and Business Media LLC,United Kingdom,Yuhui Jing; Chengliang Wang; Yu Chen; Haoming Wang; Teng Yu; Rustam Shadiev,,29,8,9283,9311,Bibliometrics; Scopus; Field (mathematics); Systematic review; Computer science; Data science; Educational research; Management science; Library science; MEDLINE; Sociology; Social science; Engineering; Political science; Mathematics; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1007/s10639-023-12178-6,,10.1007/s10639-023-12178-6,,,0,000-467-583-617-052; 001-659-642-741-620; 001-775-507-282-562; 002-052-422-936-00X; 002-799-061-909-801; 002-933-732-200-604; 007-706-374-797-341; 011-883-363-919-528; 013-541-969-076-695; 016-653-244-253-995; 018-287-100-647-982; 018-734-640-993-001; 023-015-160-175-528; 023-518-443-208-54X; 025-392-948-151-405; 031-378-521-348-344; 031-531-051-422-754; 031-879-521-929-232; 033-417-975-949-074; 033-945-897-277-258; 035-926-197-611-031; 036-398-668-504-698; 037-649-205-091-313; 041-534-943-519-97X; 044-140-050-440-305; 046-992-864-415-70X; 047-134-478-431-993; 047-271-913-022-424; 050-732-306-288-447; 050-737-196-533-976; 051-168-231-046-567; 055-749-872-948-852; 058-470-271-139-401; 059-931-415-965-469; 063-243-095-968-710; 070-475-259-752-649; 073-765-252-167-644; 074-689-637-760-304; 075-143-966-643-047; 075-171-945-695-305; 080-977-108-232-315; 081-547-256-855-879; 084-367-175-907-746; 084-447-482-399-358; 092-538-043-559-966; 094-404-236-323-270; 096-868-972-229-547; 096-876-111-242-010; 098-620-070-333-197; 099-035-546-417-61X; 099-499-815-209-209; 101-993-116-933-71X; 102-088-531-243-659; 106-126-360-017-867; 109-011-713-482-959; 109-287-305-694-212; 116-339-119-777-116; 119-557-426-467-219; 119-916-406-578-861; 120-641-287-097-402; 130-560-124-890-252; 132-723-851-457-646; 133-786-710-573-752; 138-792-952-418-045; 148-243-502-042-424; 150-329-132-181-927; 151-395-714-088-089; 152-420-184-690-109; 159-112-285-759-021; 172-435-483-998-143; 188-561-071-048-182; 189-281-178-345-777; 192-232-464-814-519; 194-454-574-354-193,39,false,, -150-404-582-989-621,Knowledge management and sustainable entrepreneurship: a bibliometric overview and research agenda,2024-06-18,2024,journal article,Journal of Innovation and Entrepreneurship,21925372,Springer Science and Business Media LLC,,Nasser Alhamar Alkathiri; Foued Ben Said; Natanya Meyer; Mohammad Soliman,"AbstractThe current work highlights the evolution in knowledge management for sustainable entrepreneurship research by analyzing the key trends and major concepts. Additionally, the knowledge structures of such research themes were analyzed and mapped. Moreover, this paper seeks to present a research agenda concerning the study subject. It employed an integrated bibliometric approach and systematic review of knowledge management and sustainable entrepreneurship research by conducting two main procedures, namely domain analysis (i.e., key trends and evolution) and knowledge structures analysis (i.e., intellectual, social, and conceptual structure). A total of 233 documents were obtained from Scopus and Web of Science datasets and analyzed using both R 4.1.2 and VOSviewer software. The findings demonstrated that the contributors (i.e., the authors, nations, journals, and institutions) produced a discernible evolution in the body of knowledge on the themes of knowledge management and sustainable business within the designated period. Furthermore, science mapping approaches deeply grasp the social, conceptual, and intellectual structures of such research themes. This current work is considered one of the first attempts to systematically review, analyze, and visualize the scientific productions on knowledge management and sustainable entrepreneurship. The findings of the current work also offer a solid understanding and insights into the potential directions for the research agenda in these disciplines.",13,1,,,Entrepreneurship; Knowledge management; Political science; Business; Regional science; Sociology; Computer science; Law,,,,,https://innovation-entrepreneurship.springeropen.com/counter/pdf/10.1186/s13731-024-00387-3 https://doi.org/10.1186/s13731-024-00387-3,http://dx.doi.org/10.1186/s13731-024-00387-3,,10.1186/s13731-024-00387-3,,,0,001-707-018-442-153; 005-768-752-856-507; 006-087-575-907-66X; 008-096-710-533-283; 008-306-710-592-358; 008-417-185-917-514; 008-921-730-525-069; 010-391-746-009-719; 010-403-577-735-896; 010-442-924-794-711; 010-854-534-444-434; 011-216-321-383-383; 011-561-241-885-604; 011-613-261-389-36X; 012-498-790-958-172; 024-041-227-810-991; 024-187-200-384-293; 026-046-165-643-168; 026-169-050-342-031; 026-571-709-667-084; 028-018-597-591-212; 029-698-509-669-39X; 029-922-726-890-414; 031-259-317-935-208; 031-589-747-331-473; 035-257-021-821-275; 035-953-579-141-278; 036-167-240-255-434; 040-560-131-598-353; 041-240-421-330-527; 041-902-264-561-013; 042-758-723-270-841; 044-607-069-225-708; 045-368-114-501-494; 046-992-864-415-70X; 047-592-847-811-624; 049-272-076-807-044; 053-477-540-250-117; 055-749-710-314-451; 058-414-131-544-37X; 061-193-282-012-137; 063-050-662-896-530; 063-446-003-584-77X; 065-010-405-236-060; 066-495-424-854-440; 067-349-706-056-114; 067-482-686-660-498; 068-639-173-304-948; 078-217-300-521-72X; 082-430-054-790-904; 090-263-716-681-040; 098-518-442-605-341; 098-899-182-549-68X; 100-294-259-882-658; 101-752-490-869-458; 101-797-152-396-853; 105-894-474-735-766; 107-123-378-399-51X; 111-924-174-328-001; 114-306-424-542-379; 118-660-434-767-085; 121-138-254-046-615; 124-620-744-142-487; 128-912-900-385-246; 129-612-123-228-44X; 140-548-511-774-076; 147-724-863-924-60X; 148-978-692-590-823; 150-488-587-805-976; 150-777-091-729-536; 156-957-205-130-49X; 163-020-318-182-57X; 167-367-947-158-810; 171-581-685-607-939; 179-608-372-698-452,13,true,cc-by,gold -151-121-541-132-919,Contemporary research trends in response robotics,2022-03-26,2022,journal article,ROBOMECH Journal,21974225,Springer Science and Business Media LLC,,Mehdi Dadvar; Soheil Habibian,"AbstractThe multidisciplinary nature of response robotics has brought about a diversified research community with extended expertise. Motivated by the recent accelerated rate of publications in the field, this paper analyzes the research trends, statistics, and implications of the literature from bibliometric standpoints. The aim is to study the global progress of response robotics research and identify the contemporary trends. To that end, we investigated the collaboration mapping together with the citation network to formally recognize impactful and contributing authors, publications, sources, institutions, funding agencies, and countries. We found how natural and human-made disasters contributed to forming productive regional research communities, while there are communities that only view response robotics as an application of their research. Furthermore, through an extensive discussion on the bibliometric results, we elucidated the philosophy behind research priority shifts in response robotics and presented our deliberations on future research directions.",9,1,,,,,,,,,http://dx.doi.org/10.1186/s40648-022-00221-z,,10.1186/s40648-022-00221-z,,,0,000-054-946-539-554; 000-524-928-933-252; 003-365-213-189-654; 004-049-523-315-208; 011-257-370-085-076; 013-507-404-965-47X; 013-650-114-904-996; 014-543-879-002-321; 017-959-237-992-384; 018-276-414-854-42X; 018-701-118-420-322; 019-337-221-424-143; 019-479-808-388-771; 022-498-123-567-197; 023-984-744-813-397; 024-080-282-087-099; 026-542-828-292-729; 028-539-184-463-54X; 028-927-693-027-126; 030-224-150-140-529; 033-753-929-919-520; 035-086-261-863-26X; 036-866-763-754-665; 041-788-951-612-170; 048-821-569-020-699; 049-391-379-302-694; 054-651-995-610-868; 055-937-000-332-450; 057-731-734-769-028; 057-776-766-700-809; 058-936-940-117-122; 061-031-692-530-920; 063-370-809-971-711; 063-516-910-599-079; 063-701-945-173-70X; 069-646-193-492-247; 081-647-105-310-124; 085-661-717-905-985; 093-880-162-236-238; 097-639-987-112-808; 097-796-530-884-858; 103-708-456-689-546; 103-766-757-334-760; 105-677-156-493-924; 121-941-425-375-898; 122-868-158-330-561; 123-465-312-338-757; 133-614-866-850-399; 133-635-629-049-39X; 137-900-533-609-655; 142-381-579-229-18X; 154-548-249-395-027; 155-820-494-034-029; 157-225-937-395-47X; 160-847-754-973-753; 180-782-159-981-768,2,true,cc-by,gold -151-252-898-292-165,Visual Analysis of Knowledge Networks for International Brands and Service Quality Based on Bibliometrix,2023-04-02,2023,journal article,"Frontiers in Business, Economics and Management",2766824x,Darcy & Roy Press Co. Ltd.,,Xingyu Jiang; Wenxin Li; Jie Zhou; Xilei Feng; Zhengbo He; Zhengsheng Liang," In recent years, the research field of brand and service quality has been highly concerned by international scholars. Based on international literature, this paper analyzes the spatial distribution characteristics, dynamic and static structure and evolution characteristics of brand and service quality network. According to the relevant literature of Web of Science database as research samples, the Bibliometrix knowledge network visualization analysis software is used to conduct data mining on the research results and hot spots of brand and service quality, so as to provide theoretical reference for the theoretical research and practical exploration of this topic research field.",8,2,87,89,Service (business); Visualization; Field (mathematics); Computer science; Data science; Quality (philosophy); Service quality; Knowledge management; Software; World Wide Web; Data mining; Business; Marketing; Philosophy; Mathematics; Epistemology; Pure mathematics; Programming language,,,,,http://drpress.org/ojs/index.php/fbem/article/download/6944/6733 https://doi.org/10.54097/fbem.v8i2.6944,http://dx.doi.org/10.54097/fbem.v8i2.6944,,10.54097/fbem.v8i2.6944,,,0,028-773-965-609-420; 034-581-528-839-069; 099-401-243-975-523; 137-421-958-596-345,0,true,cc-by,hybrid -151-463-808-495-381,A bibliometric analysis of Mycobacterium bovis BCG research trends from 1990 to 2023.,2024-11-07,2024,preprint,,,Microbiology Society,,Benjamin Moswane; Olusesan Adeyemi Adelabu; Jolly Musoke,"Introduction; ; Mycobacterium bovis bacilli Calmette-Guèrin (BCG) vaccine is a live attenuated vaccine used against Tuberculosis (TB). BCG was produced from Mycobacterium bovis via the attenuation process by Albert Calmette and Camille Guèrin.; ; Aim; ; R-Bibliometrix was used for a bibliometric analysis on M. bovis BCG research from 1990 – 2023.; ; Methodology; ; Scopus database was used for the analysis and focused on terms related to the BCG vaccine. The data was processed and analysed through the Biblioshiny and Bibliometrix tools in R (version 4.3.3) and key metrics such as the most frequently cited papers, and author contributions were extracted. Figures were also generated for article output, citation averages, relevant keywords, and institution affiliations.; ; Results; ; The documents used totalled 1143 and were obtained from 519 sources. The most cited document was Behr 1999 with 1358 total citations (TCs), and the journal with the most publications in this field was the Vaccine Journal. The author with the most publications was Buddle BM (34 articles) and the most relevant institution was the University of Cape Town whilst the USA was the leading country in terms of single and multiple-country publications.; ; Conclusion; ; Considering that TB is still a public health problem, the current trends in M. bovis BCG research are warranted.",,,,,Mycobacterium bovis; Geography; Medicine; Tuberculosis; Mycobacterium tuberculosis; Pathology,,,,"Council for Scientific and Industrial Research, South Africa",https://www.microbiologyresearch.org/deliver/fulltext/acmi/10.1099/acmi.0.000949.v1/acmi.0.000949.v1.1.pdf?itemId=/content/reviewreports/10.1099/acmi.0.000949.v1.1&mimeType=pdf https://doi.org/10.1099/acmi.0.000949.v1,http://dx.doi.org/10.1099/acmi.0.000949.v1,,10.1099/acmi.0.000949.v1,,,0,,0,true,cc-by,green -151-586-908-643-775,Science Mapping Nuclear Reaction Cross Section Calculations,2025-04-17,2025,preprint,,,MDPI AG,,Hasan Özdoğan; Gençay Sevim; Yiğit Ali Üncü,"In this study, we examined the literature for cross section calculations from 2019 to 2023 using the ISI Web of Science (WOS) database to understand the dynamics of scientific communication. Our primary objective was to perform a bibliometric analysis and model networks among authors, texts, sources, citations, keywords, organizations, and countries. Using the R tool &quot;Bibliometrix&quot; and descriptive statistical techniques, we identified significant publication trends in co-authorship, citation patterns, institutional collaborations, and the geographic distribution of authorship. Our findings highlight the importance of international collaboration and interdisciplinary research. Our analysis for cross section calculations has uncovered significant publication trends, particularly regarding co-authorships, citation patterns, institutional collaborations, and the geographic origins of authors.",,,,,Section (typography); Cross section (physics); Nuclear science; Nuclear physics; Computer science; Physics; Operating system; Quantum mechanics,,,,,,http://dx.doi.org/10.20944/preprints202504.1493.v1,,10.20944/preprints202504.1493.v1,,,0,,0,true,,bronze -151-827-146-477-559,Green manufacturing practices: a bibliometric and thematic analysis,,2023,journal article,International Journal of Bibliometrics in Business and Management,20570538; 20570546,Inderscience Publishers,,Mukesh Kumar; Vikrant Sharma,"Green manufacturing provides cost-effective ways to address environmental concerns. This study discusses the significant facets and current practices of green manufacturing. Between 1995 and the early 2020s, a bibliometric analysis of 300 studies was conducted to identify research activity on green manufacturing practices. The data is then analysed using the bibliometrix R package. Our study employed scientific methods to comb through a large body of literature. To determine influence, we look for highly cited articles and authors. The paper examines the literature on current topics, impediments to literature growth, and potential future research areas. Green manufacturing has grown steadily. JCP and JMTM are the top contributing journals. Most influential authors in this field are Ramayah and Sarkis. Thematic analysis reveals the importance of emphasising 'green', 'performance', and 'sustainability' in research design. These findings can be used by educators, researchers, and stakeholders to promote green manufacturing.",2,3,264,282,Thematic analysis; Sustainability; Thematic map; Scientific literature; Field (mathematics); Business; Knowledge management; Sociology; Computer science; Qualitative research; Geography; Social science; Ecology; Paleontology; Cartography; Mathematics; Pure mathematics; Biology,,,,,,http://dx.doi.org/10.1504/ijbbm.2023.134439,,10.1504/ijbbm.2023.134439,,,0,,0,false,, -151-939-569-337-327,A Bibliometric Review of Reinforced Soil Wall Research Topics,2024-05-07,2024,journal article,International Journal of Geosynthetics and Ground Engineering,21999260; 21999279,Springer Science and Business Media LLC,,Khashayar Malekmohammadi; Ivan P. Damians,"AbstractReinforced soil or mechanically stabilized earth (MSE) wall structures offer straightforward construction techniques as an alternative to conventional retaining earth walls. The benefits of MSE wall structures are their low cost, rapid construction, minimal ground occupation, and high tolerance for differential settlements. In the past, a vast amount of research has been conducted on this specific topic, but there is no state-of-the-art overview on the general reinforced soil walls subject. In this paper, a bibliometric review of MSE walls literature is carried out to provide multiple data points regarding the state-of-the-art in MSE wall publications. To present/demonstrate the main traditional applications, current utility, and last developments of MSE walls, a thematic/keyword cluster categorization is performed to catalog and organize the numerous applications analyzed and published in the last 4 decades. Furthermore, a discussion of MSE wall characteristics is conducted to assist researchers in expanding their understanding of potential future research areas.",10,3,,,Computer science; Thematic map; Categorization; Civil engineering; Operations research; Engineering; Geography; Artificial intelligence; Cartography,,,,Universitat Politècnica de Catalunya,https://link.springer.com/content/pdf/10.1007/s40891-024-00537-3.pdf https://doi.org/10.1007/s40891-024-00537-3,http://dx.doi.org/10.1007/s40891-024-00537-3,,10.1007/s40891-024-00537-3,,,0,001-610-226-265-090; 002-140-150-678-181; 003-204-291-460-246; 003-409-671-483-975; 003-595-895-400-843; 004-873-789-419-640; 005-021-840-621-163; 006-192-270-245-639; 006-272-205-352-905; 007-409-670-287-222; 008-043-941-437-10X; 008-753-366-664-651; 009-313-497-212-644; 010-442-924-794-711; 010-678-178-296-729; 012-149-583-765-954; 013-045-438-020-315; 013-507-404-965-47X; 014-241-444-851-902; 014-455-235-701-530; 015-737-676-310-908; 016-059-148-606-912; 016-712-810-975-261; 016-727-476-996-703; 016-781-111-000-819; 018-265-432-947-108; 018-351-696-040-404; 018-774-215-306-043; 019-467-567-016-652; 020-503-078-926-357; 022-101-442-906-063; 022-752-233-371-030; 022-939-248-493-049; 023-115-065-213-264; 024-222-890-151-796; 025-201-247-954-809; 025-245-514-573-82X; 025-385-286-877-753; 026-009-802-880-770; 026-707-866-036-139; 027-472-923-033-050; 028-460-057-605-54X; 028-497-088-754-758; 029-648-688-764-951; 030-309-579-189-440; 030-852-464-483-783; 031-063-564-181-058; 031-254-230-707-322; 031-768-936-217-315; 032-096-219-208-122; 032-927-333-043-127; 033-008-104-028-731; 033-430-835-628-953; 033-786-198-162-616; 033-949-150-586-165; 034-128-400-289-277; 034-612-894-024-475; 035-261-754-972-419; 035-333-277-918-152; 035-668-932-943-560; 036-084-648-838-752; 036-488-259-557-907; 036-565-085-713-784; 037-845-359-552-125; 038-035-150-045-351; 038-618-262-873-375; 040-890-075-090-994; 041-694-760-699-202; 041-748-660-838-093; 042-291-868-672-554; 043-009-054-727-610; 043-589-495-050-506; 043-607-998-371-439; 044-058-769-665-625; 044-201-779-322-449; 044-460-840-182-403; 044-521-751-374-485; 044-791-033-618-449; 045-070-690-076-666; 045-987-577-559-396; 049-677-860-930-025; 050-617-288-225-35X; 051-228-964-206-224; 052-234-056-707-071; 052-410-513-959-232; 054-236-290-925-941; 056-500-283-934-957; 056-977-860-530-441; 057-286-665-667-040; 057-441-443-941-646; 057-473-116-482-370; 057-777-174-163-020; 057-853-371-567-966; 062-324-012-360-08X; 063-168-799-639-862; 063-831-846-803-53X; 066-467-218-095-385; 066-703-770-493-768; 067-007-298-657-913; 067-439-859-688-445; 067-471-381-287-174; 067-473-882-100-215; 069-209-750-298-32X; 069-719-005-247-987; 070-281-660-860-915; 070-487-700-609-05X; 075-201-653-635-487; 078-887-877-893-547; 078-973-691-772-158; 079-796-424-053-134; 080-311-534-085-652; 080-336-488-104-488; 080-750-763-176-173; 080-903-728-932-134; 081-245-158-556-070; 082-373-664-685-556; 085-373-150-964-274; 085-679-219-266-282; 086-753-988-328-694; 087-155-015-530-825; 087-574-737-111-231; 087-903-943-363-450; 088-000-716-103-578; 090-579-339-853-783; 091-076-498-222-227; 092-740-292-256-818; 095-342-194-255-083; 095-631-605-752-545; 097-111-198-013-895; 097-209-459-341-21X; 097-852-424-648-695; 100-014-221-378-30X; 100-566-256-825-056; 102-235-510-971-275; 102-515-194-834-530; 102-949-070-502-057; 103-990-812-957-458; 105-490-846-167-325; 105-819-931-981-170; 105-912-416-987-355; 107-352-569-843-504; 107-418-577-360-763; 107-559-425-506-937; 115-032-801-064-941; 115-508-614-472-967; 115-550-045-635-074; 116-028-479-199-534; 117-151-373-113-819; 118-983-005-966-867; 121-665-263-706-296; 122-827-252-276-011; 123-820-971-719-493; 125-571-130-490-557; 128-309-549-540-803; 131-645-946-753-336; 133-184-044-500-552; 135-259-675-490-625; 135-632-003-090-103; 137-763-030-823-395; 141-157-924-672-471; 141-282-999-485-673; 142-619-122-124-764; 144-074-926-013-774; 144-195-704-864-259; 147-091-967-589-319; 148-788-638-123-442; 149-013-492-911-595; 150-356-071-873-180; 150-498-260-965-918; 150-706-280-965-118; 150-765-813-241-535; 150-839-735-665-146; 151-568-419-314-664; 153-315-876-473-932; 153-419-689-677-16X; 153-680-099-590-960; 158-348-078-271-925; 162-648-410-041-451; 163-553-963-976-622; 165-440-539-124-860; 166-044-788-618-281; 167-275-131-508-453; 167-318-976-059-546; 168-696-777-266-969; 175-575-895-844-355; 175-791-524-138-802; 175-948-196-179-041; 178-550-225-449-151; 179-889-762-052-36X; 181-279-609-211-807; 183-654-269-033-040; 187-184-653-252-645; 190-553-684-883-350; 191-225-203-847-564; 192-169-908-769-247,2,true,cc-by,hybrid -152-040-838-732-722,Advancements in inventory management within the agricultural supply chain: implications for waste reduction and sustainability,2024-09-09,2024,journal article,Management Review Quarterly,21981620; 21981639,Springer Science and Business Media LLC,,Luis A. Flores; Isidro Jesús González-Hernández; Armida Patricia Porras-Loaiza; Craig Watters,,,,,,Sustainability; Agriculture; Business; Supply chain; Supply chain management; Natural resource economics; Environmental economics; Environmental planning; Waste management; Environmental science; Economics; Engineering; Geography; Marketing; Ecology; Archaeology; Biology,,,,,,http://dx.doi.org/10.1007/s11301-024-00463-8,,10.1007/s11301-024-00463-8,,,0,000-028-526-298-556; 001-155-836-460-086; 001-773-103-377-822; 001-798-589-843-141; 004-940-020-943-256; 005-015-994-444-55X; 005-840-375-230-667; 006-160-361-106-347; 006-838-856-850-449; 007-297-662-001-796; 011-779-071-036-598; 011-984-954-245-177; 013-122-054-966-095; 013-507-404-965-47X; 013-603-563-235-458; 013-772-772-516-480; 014-146-632-333-293; 014-715-628-931-757; 015-208-017-013-498; 016-707-350-876-150; 017-750-600-412-958; 019-492-977-265-242; 019-925-449-493-074; 021-102-149-543-96X; 022-710-995-238-548; 027-200-740-855-650; 027-832-502-042-828; 028-932-224-395-491; 029-420-167-353-195; 029-823-009-382-835; 029-906-205-870-119; 030-087-538-365-101; 032-494-836-050-774; 033-385-621-933-899; 038-895-108-170-335; 039-681-661-069-534; 039-957-070-894-668; 040-505-337-442-15X; 040-552-308-350-194; 043-639-650-762-144; 045-592-889-921-255; 046-992-864-415-70X; 049-969-971-355-793; 050-013-190-743-434; 056-558-202-316-172; 058-477-290-975-538; 058-583-256-042-813; 059-422-689-528-949; 060-921-496-179-027; 062-200-727-574-853; 062-914-281-039-77X; 063-116-348-737-872; 064-569-266-770-415; 065-750-102-649-419; 067-678-738-591-274; 068-719-101-026-870; 069-758-661-058-369; 070-991-282-066-330; 072-046-361-881-540; 074-741-862-751-67X; 076-487-731-037-590; 076-508-875-174-615; 080-253-103-975-458; 080-436-406-243-416; 080-454-606-459-210; 080-682-789-982-980; 082-757-724-823-299; 083-233-429-885-517; 085-033-731-498-653; 085-448-853-914-402; 086-359-654-910-347; 086-359-684-264-518; 089-754-280-324-982; 096-321-859-352-149; 096-441-861-666-776; 097-540-118-836-273; 098-648-038-105-666; 104-495-326-573-684; 110-138-546-258-100; 113-459-162-876-15X; 114-539-296-954-404; 116-216-506-753-034; 121-497-690-131-984; 122-025-756-931-871; 123-978-757-826-618; 127-008-610-054-789; 127-975-637-406-696; 130-123-930-088-664; 134-248-454-369-848; 134-892-698-123-139; 139-023-120-045-151; 150-849-428-438-196; 169-536-268-288-020; 169-548-922-152-928; 172-391-418-790-539; 188-554-150-670-011; 192-527-358-069-066,2,false,, -152-055-228-064-239,A bibliometric analysis of research trends and hotspots of pilocytic astrocytoma from 2004 to 2023.,2024-12-26,2024,journal article,Neurosurgical review,14372320; 03445607,Springer Science and Business Media LLC,Germany,Qingtian Liang; Zuqing Wu; Sihan Zhu; Yizhi Du; Zhuqing Cheng; Yinsheng Chen; Fuhua Lin; Jian Wang,"Pilocytic astrocytoma (PA) is a WHO grade I neoplasm with a favorable prognosis. It is the most common pediatric benign tumor. Recently, PA has attracted more and more attention and discussion from scholars. The aim of this study is to comprehensively generalize the evolution of this field over the past two decades through bibliometric analysis and to predict future research trends and hotspots. The literature over the last two decades (2004-2023) related to PA was obtained from the Web of Science Core Collection (WoSCC) database. Bibliometric analyses were conducted based on the following aspects: (1) Annual publication trends; (2) Publications, citations/co-citations of different countries/institutions/journals/authors; (3) the map of Bradford's Law and Lotka's Law for core journals and author productivity; (4) Co-occurrence, cluster, thematic map analysis of keywords. All analyses were performed on VOSviewer and R bibliometrix package, and Excel 2024. Our results showed that research on PA displayed a considerable development trend in the past 20 years. The USA had a leading position in terms of scientific outputs and collaborations. Meanwhile, German Cancer Research Center contributed the most publications. Child's Nervous System had the highest number of publications and Acta Neuropathologica was the most co-cited journal on this subject. Gutmann, D.H. and Louis, D.N. were the authors with the most articles and co-citations in this field. The research emphases were molecular mechanisms, neurofibromatosis, pilomyxoid astrocytoma, differential diagnosis, and therapy. We systematically analyzed the literature on PA from a bibliometric perspective. The demonstrated results of the knowledge mapping would provide valuable insights into the global research landscape.",48,1,3,,Medicine; Pilocytic astrocytoma; Neurosurgery; Astrocytoma; Glioma; Radiology; Cancer research,BRAF; Bibliometrics; Low-grade glioma; Pediatric brain tumor; Pilocytic astrocytoma; Pilomyxoid astrocytoma,Humans; Astrocytoma; Bibliometrics; Biomedical Research/statistics & numerical data; Brain Neoplasms,,,,http://dx.doi.org/10.1007/s10143-024-03139-9,39724457,10.1007/s10143-024-03139-9,,PMC11671565,0,000-667-231-896-402; 001-547-116-916-500; 001-780-570-701-56X; 002-052-422-936-00X; 003-091-592-612-524; 004-133-037-404-776; 004-271-452-382-629; 005-728-838-639-435; 005-980-760-558-559; 006-151-469-134-126; 006-782-064-029-548; 007-250-033-985-122; 007-566-610-109-220; 008-994-929-520-764; 010-902-784-132-47X; 011-628-115-981-439; 011-739-145-217-492; 012-202-514-105-733; 012-354-689-710-292; 012-938-328-621-162; 013-507-404-965-47X; 015-357-330-078-625; 017-178-374-674-292; 018-735-895-155-59X; 019-647-077-933-456; 022-344-335-351-986; 022-533-886-094-878; 024-704-858-674-759; 025-685-896-376-993; 026-128-607-556-192; 026-256-662-453-23X; 026-292-562-352-077; 031-895-307-949-750; 032-261-774-078-300; 032-317-993-462-206; 033-249-799-758-366; 035-745-354-405-109; 037-398-862-966-18X; 038-387-612-734-821; 038-755-278-520-444; 039-822-817-336-042; 040-856-603-491-865; 043-094-342-909-418; 046-762-575-381-570; 046-992-864-415-70X; 046-995-067-048-437; 048-548-678-305-699; 050-036-108-693-477; 054-937-841-311-658; 055-385-197-088-734; 056-896-055-077-643; 057-058-693-769-402; 057-067-164-703-293; 058-025-684-078-12X; 058-467-988-848-072; 059-433-137-230-478; 062-913-733-434-144; 063-236-194-040-971; 064-459-277-369-363; 064-614-700-919-404; 067-535-781-926-190; 068-125-544-597-500; 070-006-355-489-498; 070-224-034-641-001; 070-436-595-705-559; 071-353-924-790-866; 072-634-730-248-734; 073-399-557-279-332; 074-855-136-085-145; 075-351-699-403-706; 076-069-720-623-007; 076-191-133-555-686; 077-479-360-419-093; 080-885-029-400-896; 081-912-971-698-182; 083-246-464-214-973; 085-233-009-062-330; 090-532-856-428-533; 092-578-813-486-932; 093-712-395-991-784; 101-875-627-929-897; 111-513-889-421-641; 116-329-778-643-868; 119-764-467-495-39X; 122-859-371-388-880; 124-249-028-539-164; 133-695-115-280-046; 158-958-401-672-461; 161-296-840-632-574; 166-341-475-183-222; 167-293-648-326-643; 167-373-519-239-682; 169-347-861-247-93X; 172-344-972-872-732; 181-124-646-440-91X; 189-389-912-465-330; 190-156-074-658-480,0,true,cc-by-nc-nd,hybrid -152-215-475-843-264,AI and Financial Fraud Prevention: Mapping the Trends and Challenges Through a Bibliometric Lens,2025-06-12,2025,journal article,Journal of Risk and Financial Management,19118074,MDPI AG,,Luiz Moura; Andre Barcaui; Renan Payer,"This study systematically reviews academic research on artificial intelligence (AI) in financial fraud prevention. Employing a bibliometric approach, we analyzed 137 peer-reviewed articles published between 2015 and 2025, sourced from Scopus, Web of Science, and ScienceDirect. Using Bibliometrix, we mapped the field’s intellectual structure, collaboration patterns, and thematic clusters. Research interest has surged since 2019, led mainly by China and India, though the literature is mostly technical, with limited social science engagement. Three main themes emerged: AI-based fraud detection models, blockchain and fintech integration, and big data analytics. Despite growing output, international collaboration and focus on ethical, regulatory, and organizational issues remain limited. These insights provide a foundation for advancing both research and practical AI-driven fraud mitigation.",18,6,323,,,,,,,,http://dx.doi.org/10.3390/jrfm18060323,,10.3390/jrfm18060323,,,0,000-938-927-783-23X; 004-239-413-234-842; 004-278-936-146-018; 005-224-557-803-455; 008-303-055-735-856; 009-544-262-051-40X; 009-693-854-580-355; 013-507-404-965-47X; 014-792-878-431-236; 016-872-571-791-520; 022-357-010-981-86X; 023-922-299-055-466; 026-485-185-568-681; 027-690-220-065-414; 028-558-388-639-555; 030-200-056-707-713; 030-795-079-916-388; 036-106-548-916-666; 037-029-897-660-670; 040-774-107-687-106; 041-946-151-498-34X; 042-167-740-200-381; 044-190-860-780-18X; 045-422-273-148-899; 045-484-225-394-116; 046-506-746-243-867; 047-607-813-649-170; 050-118-034-783-806; 052-374-140-112-120; 059-325-741-600-342; 063-062-965-947-698; 063-580-094-707-823; 065-010-405-236-060; 068-658-045-627-690; 072-658-198-050-962; 080-040-083-961-550; 081-538-226-925-720; 082-317-357-149-95X; 083-237-079-564-497; 090-468-717-430-904; 100-880-808-170-576; 102-890-331-933-442; 112-357-931-498-592; 118-601-279-333-155; 121-887-420-387-561; 122-903-899-898-059; 124-814-014-669-995; 137-443-055-729-730; 145-010-101-040-405; 146-165-688-336-282; 147-710-245-426-454; 151-055-112-347-097; 151-253-921-351-632; 153-103-538-350-548; 157-029-518-288-823; 159-114-673-053-476; 160-750-035-039-12X; 160-906-212-710-235; 161-918-730-164-849; 166-282-848-938-409; 166-833-444-590-088; 173-148-267-003-310; 174-702-227-019-205; 181-815-866-088-48X; 185-165-651-978-331; 185-774-871-143-508; 193-269-004-515-097; 193-981-035-324-399; 194-028-088-616-686,0,false,, -152-375-130-141-702,Advancements and emerging trends in ophthalmic anti-VEGF therapy: a bibliometric analysis.,2024-09-05,2024,journal article,International ophthalmology,15732630; 01655701,Springer Science and Business Media LLC,Netherlands,Jie Deng; YuHui Qin,,44,1,368,,Medicine; VEGF receptors; Ophthalmology; Internal medicine,Anti-VEGF agents; Bibliometrics; Neovascularization; Ophthalmology,Humans; Angiogenesis Inhibitors/administration & dosage; Vascular Endothelial Growth Factor A/antagonists & inhibitors; Bibliometrics; Ophthalmology/trends; Intravitreal Injections,Angiogenesis Inhibitors; Vascular Endothelial Growth Factor A,The Open Fund Project of First-Class Disciplines of Hunan University of Chinese Medicine (2022ZYX04); The Key Discipline Construction Project of Ophthalmology of Traditional Chinese Medicine of the National Administration of Traditional Chinese Medicine (ZK1801YK015),,http://dx.doi.org/10.1007/s10792-024-03299-z,39235545,10.1007/s10792-024-03299-z,,,0,000-133-423-373-132; 000-160-880-462-089; 000-667-231-896-402; 004-559-378-182-161; 005-719-835-104-895; 006-674-881-148-08X; 007-863-489-105-009; 008-212-389-810-963; 008-882-074-534-987; 009-085-292-244-157; 009-983-836-331-043; 012-629-803-852-594; 012-675-202-530-984; 013-598-512-335-260; 014-076-337-925-05X; 014-140-560-568-060; 014-390-415-499-179; 017-188-738-401-922; 018-592-462-439-575; 019-910-895-694-317; 021-730-533-395-786; 034-906-622-585-926; 036-328-849-210-812; 042-216-851-976-64X; 043-971-840-130-054; 044-495-807-325-484; 044-609-362-645-84X; 049-147-232-698-853; 049-504-058-039-889; 050-419-898-430-468; 053-767-409-123-310; 055-497-099-256-606; 056-268-118-868-411; 063-148-539-693-450; 063-219-336-655-150; 066-366-349-519-093; 066-436-166-280-703; 067-038-028-150-268; 071-217-751-444-52X; 071-523-130-770-184; 078-179-557-130-420; 079-467-795-855-534; 079-520-619-006-103; 080-379-550-004-315; 080-556-765-638-539; 091-142-636-322-879; 096-467-955-293-355; 116-350-313-822-029; 118-491-814-991-148; 135-118-905-751-677; 141-770-516-078-794; 147-955-307-335-247; 151-513-229-396-218; 165-535-724-443-814; 179-765-825-726-911; 194-939-709-145-870,3,false,, -152-440-504-405-089,"50 years of rare earth research in Malaysia: Past, future trend and what is missing? A bibliometric analysis",,2024,conference proceedings article,AIP Conference Proceedings,0094243x; 15517616; 19350465,AIP Publishing,,Nurul Ain Ismail; Mohd Amirul Mukmin Abdullah; Mohd Aizudin Abd Aziz; Badhrulhisham Abdul Aziz,"The bibliometric analysis was conducted using R Bibliometrix software on 4,876 articles related to rare earth published by author from Malaysia. All the articles are indexed in Scopus from 1971 to 2023. The multidimensional analytical approach provided holistic view of the scope of rare earth research in Malaysia and its progression, the major topics, institutes, trends and gaps. Based on the general descriptive data analysis, the results showed that rare earth research has gained influence in Malaysia since 2009. A clustering analysis of the retrieved keywords showed that fiber lasers and saturable absorber in rare earth was the most frequently discussed topic. The study also revealed a major gap in this area especially on the upstream and middle stream study of rare earth. The gaps should be filled in order to position Malaysia as one of the rare earth powerhouse.",3063,,40011,040011,Computer science; Rare earth; Data science; Earth science; Geology,,,,,https://pubs.aip.org/aip/acp/article-pdf/doi/10.1063/5.0201480/19710271/040011_1_5.0201480.pdf https://doi.org/10.1063/5.0201480,http://dx.doi.org/10.1063/5.0201480,,10.1063/5.0201480,,,0,001-688-540-167-077; 002-698-984-038-343; 003-744-780-922-47X; 005-181-501-918-061; 012-577-308-927-50X; 013-680-099-993-341; 014-809-110-522-34X; 015-589-368-115-199; 016-337-214-341-009; 018-720-112-465-670; 019-263-005-540-722; 020-702-466-695-10X; 022-803-442-739-839; 028-138-789-013-237; 033-831-565-767-992; 037-364-040-118-426; 040-802-263-991-500; 042-085-732-800-070; 042-527-152-967-830; 042-911-354-037-478; 047-798-581-297-309; 052-218-464-372-67X; 054-483-031-232-25X; 056-074-381-018-574; 063-895-141-619-882; 065-919-194-002-161; 068-617-306-490-135; 069-777-700-806-491; 072-097-457-641-154; 073-417-163-849-685; 076-447-296-528-670; 078-010-601-315-892; 080-798-606-922-040; 081-119-001-481-480; 081-307-512-026-234; 087-000-800-396-688; 088-005-682-010-914; 088-632-236-532-168; 102-950-118-954-852; 113-282-079-783-066; 119-023-830-980-480; 119-483-246-256-722; 121-540-454-688-044; 123-903-958-015-962; 126-573-737-569-101; 130-194-594-609-034; 133-477-536-747-390; 134-186-217-604-380; 137-216-448-653-802; 139-559-641-408-814; 156-907-547-679-110; 157-990-135-258-252; 168-767-670-437-102; 180-308-635-016-590,1,true,,bronze -152-490-973-524-764,A Systematic Literature Review on the Role of Artificial Intelligence in Entrepreneurial Activity,2023-02-16,2023,journal article,International Journal on Semantic Web and Information Systems,15526283; 15526291,IGI Global,United States,Cristina Blanco-González-Tejero; Belén Ribeiro-Navarrete; Enrique Cano-Marin; William C. McDowell,"

New models of entrepreneurship are emerging because of increasing digitalization and the development of artificial intelligence (AI). There is a lack of existing research on the intersection between digitalization and entrepreneurship. Therefore, this systematic literature analysis aims to expand knowledge in this area and provide a semantic analysis of existing contributions. Following the SPAR-4-SLR protocol, it analyzes 520 scientific articles from the Dimensions.ai database up to July 2022. The methodology uses natural language processing (NLP) and tools such as bibliometrix and VosViewer, which reveal the main characteristics of the titles and texts of the abstracts and their links with the numbers of citations and with scientific impact. This study provides guidelines and clear recommendations for scientists to focus their scientific research on AI and entrepreneurship and entrepreneurs by including the link between AI and entrepreneurship in their strategies. As future lines of research, the authors highlight the potential of using NLP in bibliometric analysis.

",19,1,1,16,Entrepreneurship; Computer science; Data science; Scientific literature; Intersection (aeronautics); Systematic review; Applications of artificial intelligence; Knowledge management; Artificial intelligence; Management science; Political science; MEDLINE; Engineering; Paleontology; Law; Biology; Aerospace engineering,,,,,https://www.igi-global.com/ViewTitle.aspx?TitleId=318448&isxn=9781668479094 https://doi.org/10.4018/ijswis.318448,http://dx.doi.org/10.4018/ijswis.318448,,10.4018/ijswis.318448,,,0,001-831-500-910-611; 001-847-580-171-949; 002-052-422-936-00X; 002-926-845-480-520; 006-420-918-875-724; 007-803-448-438-072; 008-146-495-921-306; 010-160-304-916-647; 011-112-865-135-787; 011-372-862-935-683; 011-496-129-122-14X; 011-814-956-634-019; 013-507-404-965-47X; 013-762-910-891-248; 018-427-224-615-415; 019-410-362-524-672; 019-629-243-430-514; 020-914-062-130-756; 021-187-695-321-390; 023-414-581-037-367; 025-799-641-586-986; 031-402-331-384-958; 034-885-668-549-795; 040-120-307-210-676; 040-849-039-773-224; 041-918-163-624-122; 044-558-681-952-727; 045-118-156-568-396; 047-784-432-046-832; 052-434-673-310-180; 053-598-695-896-482; 054-075-634-415-714; 059-151-757-196-21X; 068-850-003-935-61X; 069-269-558-803-618; 070-274-575-481-181; 071-844-540-139-018; 075-692-478-537-204; 077-320-486-062-195; 078-099-988-867-715; 079-280-228-157-510; 079-329-009-311-172; 079-703-098-146-339; 082-216-520-044-785; 084-926-011-346-063; 085-910-281-845-014; 087-646-817-053-211; 091-293-380-119-057; 092-274-926-085-614; 107-090-895-359-876; 107-852-424-555-350; 113-682-442-621-962; 119-897-190-401-141; 123-218-689-488-554; 129-297-302-704-07X; 142-699-387-067-243; 143-292-267-254-599; 148-740-835-107-81X; 188-533-083-472-441; 197-954-755-498-997,20,true,,gold -153-198-323-004-220,Bibliographic data and thesauraus files,2023-08-29,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Stephen Chignell; Terre Satterfield,Data for “Seeing beyond the frames we inherit: A challenge to tenacious conservation narratives” (published in People and Nature) Stephen M. Chignell and Terre Satterfield ------------------------------------------------------------------------------------------------------------------------------- This repository contains the following data files used in the above publication. Detailed information about how these data were collected and analyzed can be found at the journal website. Bibliographic data downloaded from Web of Science (raw text file format) Can be imported directly into bibliometrix/biblioshiny or VOSviewer software Bibliographic data downloaded from Web of Science (Microsoft Excel format) Can be imported directly into bibliometrix/biblioshiny software “Thesaurus” file created to disambiguate author names in VOSviewer software “Thesaurus” file created to disambiguate publication keywords in VOSviewer software “Thesaurus” file created to disambiguate author organizations in VOSviewer software,,,,,Data file; Computer science; Information retrieval; Database; World Wide Web,,,,,https://zenodo.org/record/8299592,http://dx.doi.org/10.5281/zenodo.8299592,,10.5281/zenodo.8299592,,,0,,0,true,cc-by,gold -153-232-876-107-111,"A bibliometric review of waste management and innovation: Unveiling trends, knowledge structure and emerging research fronts.",2024-09-10,2024,journal article,"Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA",10963669; 0734242x,SAGE Publications,United States,Ana Maria Ortega Alvarez; Karolína Malá; Maribel Serna Rodriguez,"The pressing challenges in waste management have motivated this comprehensive study examining prior research and contemporary trends concerning innovation and waste management. A meticulous investigation of 2264 documents (1968-2024) was conducted using bibliometrix R-tool to analyse Scopus and Web of Science databases, offering a holistic global perspective. Heightened societal concern about waste management, driven by soaring waste production from consumption patterns, requires urgent exploration of effective waste elimination and transformation systems. This study provides a comprehensive summary of the topic, delving deeply into its complexities. Through thorough analysis of global trends, it constitutes a significant stride towards identifying effective solutions, offering valuable contributions to both scientific understanding and practical applications. This research pioneers a comprehensive synthesis of innovation and waste management issues, showcasing originality and substantial contributions. The identified collaborative networks expose a lack of transnational cooperation, potentially hindering waste management innovation. Future research around waste management innovation should focus on synergies among competitors within the same industry and across industries to minimize waste and maximize resource utilization, 4.0 technologies, global waste chain impacts and challenges along with solutions for developing countries.",43,5,649,673,Competitor analysis; Scopus; Business; Originality; Circular economy; Knowledge management; Marketing; Computer science; Political science; Creativity; Ecology; MEDLINE; Law; Biology,JEL codes; Scopus; Waste management; Web of Science; bibliometrix R-Tool; innovation; literature review; network analysis,Waste Management/methods; Bibliometrics,,,,http://dx.doi.org/10.1177/0734242x241270930,39254159,10.1177/0734242x241270930,,,0,000-249-125-299-127; 002-067-124-530-257; 002-087-337-637-531; 002-721-407-214-59X; 006-750-012-058-578; 008-100-972-276-984; 009-030-098-582-445; 010-021-078-612-230; 010-065-762-504-134; 013-507-404-965-47X; 013-683-191-846-68X; 016-115-414-321-383; 016-936-798-222-306; 017-080-818-211-518; 017-750-600-412-958; 018-192-245-826-736; 018-759-180-937-084; 019-352-601-927-16X; 021-453-356-843-96X; 023-390-616-401-613; 023-472-668-349-537; 024-395-037-572-505; 025-302-119-966-613; 027-182-271-969-690; 027-881-515-966-828; 028-547-395-679-236; 028-825-458-207-816; 030-236-129-934-891; 031-076-247-002-645; 032-758-742-453-739; 033-127-677-566-360; 034-859-495-381-47X; 036-432-248-098-415; 036-599-443-095-660; 038-070-931-642-881; 039-760-915-338-817; 041-553-604-881-88X; 042-575-843-632-69X; 043-122-920-865-900; 045-422-273-148-899; 045-425-887-365-138; 046-987-161-956-95X; 046-992-864-415-70X; 049-834-485-222-401; 050-557-246-470-427; 053-540-403-555-036; 057-479-920-545-771; 061-444-463-813-13X; 062-967-788-310-759; 063-401-627-636-751; 063-577-970-751-369; 065-219-969-646-601; 067-599-145-048-027; 068-353-445-691-862; 069-663-050-556-80X; 069-758-661-058-369; 070-991-282-066-330; 071-629-582-160-390; 076-180-363-041-695; 078-004-984-339-283; 080-732-112-630-353; 081-298-850-117-743; 082-027-063-329-183; 082-723-692-096-334; 086-983-214-975-090; 089-729-951-092-277; 089-754-280-324-982; 089-900-901-585-513; 091-195-385-962-407; 096-472-527-387-204; 098-291-360-625-548; 103-141-517-446-587; 103-854-878-408-148; 105-959-214-219-268; 106-689-368-820-637; 111-056-968-472-569; 112-533-001-418-656; 116-411-843-753-143; 121-834-879-605-703; 122-689-210-345-696; 124-187-743-925-055; 133-292-558-130-534; 138-232-054-169-504; 139-023-120-045-151; 141-842-769-151-822; 142-694-899-270-971; 143-899-566-916-362; 144-750-876-580-586; 145-112-212-183-801; 150-002-135-897-192; 152-068-942-867-795; 157-118-060-858-103; 169-512-949-494-309; 177-804-415-258-488; 179-326-625-020-063; 183-681-432-473-550; 184-827-346-305-484; 186-842-017-005-091; 191-877-859-251-097; 192-227-245-814-459,2,false,, -153-439-338-934-636,BIBLIOMETRIC ANALYSIS OF RESEARCH ON BEE POLLEN: GLOBAL TRENDS AND COLLABORATION PATTERNS,2023-10-15,2023,journal article,Gıda,13003070,"Association of Food Technology, Turkey",,İlginç KİZİLPİNAR TEMİZER; Duygu Nur ÇOBANOĞLU,"Bee pollen is recognized for its nutritional and health benefits, drawing attention from both the scientific community and consumers as a natural functional food. This study employed bibliometric analysis, using the R program bibliometrix package and VOS viewer, to examine scientific research on bee pollen. We were evaluated 921 articles in the Web of Science databases using the keyword 'bee pollen' published between 2011-2022. Among these, 90.45% were research articles, 6.73% were reviews, 2.06% were meeting abstracts, and 0.76% were book chapters. China led with 562 articles, followed by Brazil (330), Turkey (295), Italy (190), Portugal (189), the USA (175), and Spain (158). Bee pollen was the most used keyword, followed by pollen, propolis, and honey. This is the first bibliometric study to evaluate the researchs on bee pollen, and it is considered important in terms of organizing the scientific studies to be conducted on this subject.",48,5,1084,1098,Pollen; Bee pollen; Propolis; Web of science; China; Library science; Scientific literature; Subject (documents); Geography; Biology; Botany; Computer science; MEDLINE; Archaeology; Biochemistry,,,,,https://dergipark.org.tr/en/download/article-file/3032969 https://doi.org/10.15237/gida.gd23036,http://dx.doi.org/10.15237/gida.gd23036,,10.15237/gida.gd23036,,,0,002-052-422-936-00X; 010-265-160-064-844; 010-952-037-618-383; 011-602-657-475-631; 013-414-361-703-417; 014-411-974-706-947; 018-991-619-124-466; 020-249-874-794-315; 021-714-353-394-006; 023-521-266-375-933; 026-259-359-600-739; 026-466-816-212-136; 028-118-006-999-311; 030-070-985-228-781; 031-378-521-348-344; 031-527-111-575-436; 034-121-742-250-91X; 035-700-358-055-725; 039-945-456-209-063; 041-599-022-328-981; 041-833-173-817-486; 043-039-573-255-798; 057-286-311-076-534; 057-905-947-703-230; 063-955-915-486-094; 073-760-338-998-200; 075-542-113-655-263; 082-071-132-356-58X; 089-386-053-407-677; 090-774-342-845-059; 095-723-623-259-939; 097-541-229-463-697; 101-674-756-958-829; 102-094-294-692-039; 114-294-758-353-88X; 114-394-631-338-410; 125-055-384-730-265; 126-136-005-046-684; 143-589-261-034-058; 143-936-693-364-687; 164-620-292-961-211; 178-715-889-882-866; 179-690-311-575-673; 197-871-972-609-311,1,true,,gold -153-662-158-822-452,A bibliometric analysis of radiation-induced brain injury: a research of the literature from 1998 to 2023.,2024-08-22,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Jinxin Lan; Yifan Ren; Yuyang Liu; Ling Chen; Jialin Liu,"Radiation-induced brain injury (RIBI) is a debilitating sequela after cranial radiotherapy. Research on the topic of RIBI has gradually entered the public eye, with more innovations and applications of evidence-based research and biological mechanism research in the field of that. This was the first bibliometric analysis on RIBI, assessing brain injury related to radiation articles that were published during 1998-2023, to provide an emerging theoretical basis for the future development of RIBI.; Literature were obtained from the Web of Science Core Collection (WOSCC) from its inception to December 31, 2023. The column of publications, author details, affiliated institutions and countries, publication year, and keywords were also recorded.; A total of 2543 journal articles were selected. The annual publications on RIBI fluctuated within a certain range. Journal of Neuro-oncology was the most published journal and Radiation Oncology was the most impactful one. LIMOLI CL was the most prolific author with 37 articles and shared the highest h-index with BARNETT GH. The top one country and institutions were the USA and the University of California System, respectively. Clusters analysis of co-keywords demonstrated that the temporal research trends in this field primarily focused on imaging examination and therapy for RIBI.; This study collects, visualizes, and analyzes the literature within the field of RIBI over the last 25 years to map the development process, research frontiers and hotspots, and cutting-edge directions in clinical practice and mechanisms related to RIBI.; © 2024. The Author(s).",15,1,364,,Sequela; Medicine; Surgery,Bibliometric analysis; Clinical practice; Hotspots; Mechanisms; Radiation-induced brain injury,,,National Natural Science Foundation of China (82172680),,http://dx.doi.org/10.1007/s12672-024-01223-6,39172266,10.1007/s12672-024-01223-6,,PMC11341524,0,000-248-719-401-980; 000-341-340-607-323; 001-593-126-194-393; 001-856-723-154-316; 002-052-422-936-00X; 003-532-472-365-806; 005-520-994-908-34X; 005-662-983-252-924; 006-460-510-406-998; 006-551-062-578-692; 006-804-995-375-996; 007-100-750-684-425; 007-647-975-352-113; 007-822-986-716-897; 008-544-027-103-20X; 008-631-529-478-074; 010-168-316-482-221; 010-901-028-214-571; 013-507-404-965-47X; 013-522-306-685-373; 013-700-237-453-171; 014-100-241-643-813; 014-589-118-098-641; 015-911-697-881-049; 017-780-865-675-312; 018-735-895-155-59X; 020-080-046-935-409; 021-508-550-654-359; 022-438-558-658-990; 022-532-652-230-115; 023-435-528-706-042; 023-992-186-938-952; 024-433-350-482-770; 024-454-035-305-777; 024-822-860-211-507; 025-879-571-253-472; 026-084-893-511-005; 027-572-014-548-717; 028-053-703-787-053; 029-251-927-877-510; 033-186-626-226-438; 034-544-277-335-33X; 037-010-989-714-349; 043-321-082-566-072; 046-411-626-324-978; 047-004-056-135-638; 047-493-423-642-616; 048-238-520-839-048; 050-526-262-857-240; 054-319-574-623-746; 059-697-792-555-251; 060-897-758-234-667; 065-474-109-406-761; 068-825-480-444-958; 070-589-806-711-471; 071-193-617-925-142; 071-878-836-294-733; 075-587-465-589-967; 075-970-365-637-871; 076-140-189-722-199; 079-876-188-547-457; 080-912-572-781-951; 080-988-286-121-793; 082-428-366-909-895; 085-692-559-354-912; 090-359-943-156-998; 090-476-872-676-699; 090-553-440-083-415; 091-709-285-898-036; 092-244-073-850-048; 092-379-971-366-088; 093-633-968-755-688; 095-425-336-351-470; 096-587-717-191-165; 099-279-171-010-557; 099-553-337-146-526; 101-752-490-869-458; 104-068-657-185-807; 104-307-982-246-015; 124-044-276-675-852; 125-575-775-144-449; 125-861-435-608-304; 127-450-649-062-657; 140-846-001-747-989; 142-110-179-875-452; 142-763-004-013-883; 143-523-194-411-420; 145-553-266-971-153; 172-344-972-872-732; 177-832-547-760-355; 178-930-603-494-932; 191-912-480-965-977; 194-106-222-633-024,2,true,cc-by,gold -153-771-258-269-001,"Comment on: ""Green supply chain management/green finance: a bibliometric analysis of the last twenty years by using the Scopus database"" by Fahim, Faryal and Batiah Mahadi., (https://doi.org/10.1007/s11356-022-21764-z).",2022-10-10,2022,letter,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Waseem Hassan,,29,54,82615,82615,Scopus; Bibliometrics; Web of science; Database; Library science; Political science; MEDLINE; Computer science; Law,,Bibliometrics,,,https://link.springer.com/content/pdf/10.1007/s11356-022-23493-9.pdf https://doi.org/10.1007/s11356-022-23493-9,http://dx.doi.org/10.1007/s11356-022-23493-9,36215014,10.1007/s11356-022-23493-9,,,0,141-407-090-706-370,0,true,,bronze -153-865-743-719-763,Women's Leadership Research in Higher Education Institutions (HEIs): A Bibliometric Study,2025-03-21,2025,journal article,Manajemen dan Bisnis,24771783; 14123789,University of Surabaya,,Kania - Widyatami; A. - Sobandi,"Gender disparity in leadership positions has been a topic of discussion for a considerable amount of time, including in the context of Higher Education Institutions (HEIs). This study applied bibliometric analysis to reveal how the field evolved. The data was retrieved from the Scopus database from 1952–2023 and processed using R software’s “bibliometrix” package and the Publish and Perish applications. A range of techniques comprising performance analysis and science mapping through co-citation analysis, bibliographic coupling, and co-word analysis were performed to uncover the intellectual, knowledge, and conceptual structures that give insights regarding the trends as well as the past, present, and future of the field.",24,1,181,181,Higher education; Political science; Bibliometrics; Sociology; Library science; Computer science; Law,,,,,,http://dx.doi.org/10.24123/mabis.v24i1.813,,10.24123/mabis.v24i1.813,,,0,,0,true,cc-by,gold -154-012-292-192-836,Authorship and citation cultural nature in Density Functional Theory from solid state computational packages,2021-06-23,2021,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Marie Dumaz; Reese Boucher; Miguel A. L. Marques; Alessandra Romero,,126,8,6681,6695,Citation analysis; Data science; Relation (database); Software; Citation; Country of origin; Specialization (logic); Characterization (materials science); Field (computer science),,,,U.S. Department of Energy; U.S. Department of Energy; National Science Foundation; National Science Foundation,https://econpapers.repec.org/RePEc:spr:scient:v:126:y:2021:i:8:d:10.1007_s11192-021-04057-z https://doi.org/10.1007/s11192-021-04057-z https://link.springer.com/article/10.1007/s11192-021-04057-z https://dblp.uni-trier.de/db/journals/scientometrics/scientometrics126.html#DumazBMR21 https://link.springer.com/10.1007/s11192-021-04057-z,http://dx.doi.org/10.1007/s11192-021-04057-z,,10.1007/s11192-021-04057-z,3174270015,,0,007-292-248-155-666; 008-118-448-353-31X; 013-507-404-965-47X; 025-481-740-037-413; 028-485-360-248-515; 029-029-002-740-224; 038-202-540-977-352; 048-509-740-566-063; 050-893-918-681-677; 065-516-419-444-125; 066-315-869-941-730; 066-839-689-325-444; 073-927-434-605-202; 077-055-900-689-707; 086-003-302-341-673; 099-449-205-479-935; 101-752-490-869-458; 102-785-386-799-872; 116-880-007-548-12X; 117-856-566-119-133; 118-448-501-657-946; 119-572-790-495-473; 132-238-138-313-349; 134-290-273-835-183; 168-129-822-256-006; 183-455-244-659-061,4,false,, -154-072-281-231-347,A Biblioshiny Application Using R On Zakat Index,2023-03-17,2023,journal article,Islamic Economics Methodology,29858917,Sharia Economic Applied Research and Training (SMART) Insight,,Irni Nuraini; null Thuba Jazil,"This study aims to examine research patterns concerning the published zakat index. The studied data came from the Scopus database, which was accessed in its entirety on 13 February 2023. A total of 51 papers were retrieved. The data were analyzed with the Rstudio Bibliometrix program and biblioshiny instruments to determine the research advancements on the Zakat Index. The data demonstrates that the development of zakat index research began in 1994 and has accelerated since 2008. Al-Homaidi, E.A., is the most prolific writer on this subject. Zakat is the most commonly occurring keyword. Malaysia has the highest number of publications and citations on this topic. Malaysia's University Teknologi Mara has the most author affiliations. According to the themes in the zakat index study that has the potential to be expanded, this research has a great deal of room for growth. ;  ",2,1,,,Index (typography); Scopus; Subject (documents); Research data; Library science; Database; Political science; Computer science; World Wide Web; Law; MEDLINE,,,,,http://journals.smartinsight.id/index.php/IEM/article/download/163/157 https://doi.org/10.58968/iem.v2i1.163,http://dx.doi.org/10.58968/iem.v2i1.163,,10.58968/iem.v2i1.163,,,0,,4,true,,bronze -154-129-723-591-177,Interrelationship between trade and environment: a bibliometric analysis of published articles from the last two decades.,2023-01-10,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Lakshmana Padhan; Savita Bhat,"Extant literature indicates that the concepts of international trade and the environment are intertwined. There is a plethora of theoretical and empirical research studies that explore the relationship between the two concepts. However, no bibliometric attempts have been made to analyze these publications to understand the current research trends in the trade and environment regulation/protection/policy intersection. Hence, the present study conducted a bibliometric analysis of 1390 research articles collected from the Scopus database from 2000 to 2021. The study accomplished performance and science mapping analysis using Bibliometrix and VOSViewer software. The study shows an increasing publication trend. The most productive country was the USA (259 publications with 8400 citations), and the most productive institution was the University of California (33 publications). The study found that Cole MA was the most relevant author in this area by considering multiple matrices. By using keywords, conceptual structure, and bibliographic coupling analysis, the study suggests that future studies can be conducted on climate change, carbon leakage, climate policy, environmental protection, air pollution, economic growth, carbon dioxide emission, emission trading, abatement cost, environmental performance, green supply chain management, composition effect, carbon footprints, and multi-regional input-output model. The current study provides scholars and practitioners interested in trade and environmental interlinkages with a comprehensive overview of the domain by presenting readers with significant studies, authors, universities, concepts, and sources. Further, the study results will be helpful for scholars to get insights into the current research development trends and research themes in the trade and environmental regulation field.",30,7,17051,17075,Scopus; Regional science; Extant taxon; Empirical research; Political science; Bibliographic coupling; Bibliometrics; Environmental resource management; Geography; Library science; Citation; Environmental science; Computer science; Philosophy; MEDLINE; Epistemology; Evolutionary biology; Law; Biology,Bibliometric analysis; Bibliometrix; Environment; Performance analysis; Trade; VOSViewer,Commerce; Internationality; Air Pollution; Bibliometrics; Carbon Dioxide,Carbon Dioxide,,https://www.researchsquare.com/article/rs-1328205/latest.pdf https://doi.org/10.21203/rs.3.rs-1328205/v1,http://dx.doi.org/10.1007/s11356-023-25168-5,36626051,10.1007/s11356-023-25168-5,,,0,000-371-320-258-610; 000-427-602-001-40X; 000-793-040-027-156; 002-052-422-936-00X; 004-364-728-087-587; 004-819-527-814-707; 006-274-379-153-462; 007-063-632-033-402; 007-156-408-461-00X; 008-047-541-440-500; 008-053-394-047-282; 008-729-014-197-658; 009-422-360-689-25X; 010-082-458-062-110; 011-314-596-744-247; 013-507-404-965-47X; 015-586-822-938-491; 015-692-170-714-052; 015-770-521-570-742; 016-179-470-551-063; 016-631-878-014-147; 017-730-499-561-247; 020-837-242-401-748; 022-621-656-070-387; 022-776-124-125-320; 023-927-221-065-800; 024-745-157-416-555; 025-414-002-380-13X; 025-435-560-317-904; 025-955-798-099-846; 026-339-935-293-838; 028-237-804-419-360; 033-378-822-375-955; 034-985-998-935-718; 034-992-726-371-408; 037-091-873-048-986; 037-397-309-420-427; 037-420-363-708-467; 038-745-955-878-277; 040-335-128-628-08X; 040-901-846-954-705; 041-009-624-103-349; 042-427-895-200-114; 045-688-022-520-199; 045-777-161-498-037; 046-144-735-296-343; 046-992-864-415-70X; 047-134-478-431-993; 048-735-886-156-564; 049-275-114-077-753; 051-032-704-308-705; 051-191-019-680-873; 052-909-000-186-644; 053-152-069-458-462; 053-457-568-896-94X; 053-602-688-901-879; 054-373-879-048-698; 054-818-565-070-154; 054-831-903-718-002; 056-079-975-939-998; 056-426-226-149-95X; 056-557-853-547-922; 058-192-149-454-339; 062-251-001-546-482; 062-470-938-278-544; 062-646-753-397-682; 064-336-180-313-54X; 065-302-131-395-252; 065-516-419-444-125; 069-726-724-038-925; 070-140-527-912-078; 070-756-644-857-990; 071-110-450-502-212; 071-307-143-815-891; 072-856-861-900-730; 073-769-308-579-882; 074-962-332-783-382; 076-912-898-906-297; 078-628-303-703-672; 079-119-979-163-902; 079-496-478-759-381; 079-565-233-262-541; 081-705-067-586-287; 082-788-109-254-68X; 083-186-906-167-579; 085-611-648-184-268; 085-754-354-045-703; 086-365-772-199-008; 086-772-516-412-218; 086-881-959-784-195; 087-255-710-316-116; 087-325-422-677-882; 087-522-531-031-418; 090-706-232-527-709; 091-953-781-743-548; 094-945-486-321-325; 097-875-158-386-515; 099-295-888-821-509; 099-702-418-425-179; 100-144-966-858-346; 100-949-427-602-075; 101-306-547-993-960; 101-752-490-869-458; 105-052-792-454-889; 106-471-770-673-581; 110-132-452-427-05X; 111-835-138-647-967; 112-704-617-172-643; 113-551-891-494-006; 117-800-943-742-471; 119-116-437-228-092; 119-916-657-846-859; 120-040-246-058-26X; 121-813-144-996-86X; 122-415-544-444-960; 128-217-524-056-953; 130-602-202-936-694; 131-530-527-911-90X; 133-824-388-624-922; 139-866-514-175-229; 143-209-851-361-289; 150-785-305-541-644; 154-591-236-180-40X; 192-246-047-492-472,10,true,,green -154-180-616-884-330,Analisis Bibliometrix Publikasi Ilmiah Terkait Prevention Cyberbullying Menggunakan Web Of Scince Pada Biblioshany,2024-05-31,2024,journal article,Angkasa: Jurnal Ilmiah Bidang Teknologi,25811355; 20859503,Institut Teknologi Dirgantara Adisutjipto (ITDA),,Anita Elizabeth Wettebossy; Imam Yuadi,"Pencegahan Cyberbullying melibatkan sejumlah tindakan yang mengurangi risiko dan dampak perilaku negatif secara daring. Inisiatif ini mencakup pemahaman tentang etika digital serta edukasi dari pihak yang berwenang. Dalam hal ini penulis terdorong menganalisis sejauh mana pertumbuhan dan perkembangan publikasi ilmiah terkait prevention cyberbullying menggunakan bibliometrix dengan kata kunci prevention cyberbullying . Tujuan dan manfaat penelitian ini untuk menilai tingkat pertumbuhan publikasi ilmiah terkait topik, hal ini diharapkan agar mengurangi fakta buruk mengenai cyberbullying dan mampu memberikan kontribusi pada pemahaman masyarakat serta menyediakan landasan edukasi yang lebih baik dalam upaya pencegahan cyberbullying . Analisis data menggunakan web of science dengan kata kunci pencegahan cyberbullying memperoleh hasil sebanyak 882 dokumen tidak dibatasi. Kemudian data diolah pada aplikasi R studio, bahasa R dan bibliometrik. Hasil yang diperoleh dari data utama mencakup periode dari tahun 2007 dan 2023. Tabel tersebut menunjukkan bahwa 882 dokumen berasal dari 425 sumber termasuk jurnal dan buku, telah ditulis oleh 2.313 penulis dengan topik prevention cyberbullying . Tingkat pertumbuhan tahunan 6.26 dengan rata-rata kutipan 26.86 per dokumen dan rata-rata usia dokumen 5.25 kutipan per tahun dengan referensi 0. Dapat disimpulkan bahwa perkembangan publikasi ilmiah terkait topik telah dilakukan sejak lama.",16,1,72,72,Psychology,,,,,https://ejournals.itda.ac.id/index.php/angkasa/article/download/2058/pdf https://doi.org/10.28989/angkasa.v16i1.2058,http://dx.doi.org/10.28989/angkasa.v16i1.2058,,10.28989/angkasa.v16i1.2058,,,0,003-996-257-721-228; 010-065-762-504-134; 013-507-404-965-47X; 033-022-409-666-807; 038-175-574-558-235; 073-974-706-254-20X; 097-386-209-385-874; 105-579-594-604-189; 143-936-693-364-687,0,true,,gold -154-873-405-728-807,Research hotspots and frontiers of machine learning in renal medicine: a bibliometric and visual analysis from 2013 to 2024.,2024-10-30,2024,journal article,International urology and nephrology,15732584; 03011623,Springer Science and Business Media LLC,Netherlands,Feng Li; ChangHao Hu; Xu Luo,,57,3,907,928,Medicine; Nephrology; Bibliometrics; Data science; Internal medicine; Medical physics; Library science; Computer science,Artificial intelligence; Bibliometrics; Machine learning; Renal medicine,Machine Learning; Bibliometrics; Humans; Nephrology/trends; Biomedical Research/trends; Kidney Diseases/diagnosis,,,,http://dx.doi.org/10.1007/s11255-024-04259-3,39472403,10.1007/s11255-024-04259-3,,,0,002-052-422-936-00X; 004-421-351-194-427; 005-011-636-083-514; 005-399-659-759-330; 006-351-772-268-027; 007-125-532-622-470; 007-543-889-873-741; 007-761-850-931-604; 008-562-077-009-341; 013-261-296-086-031; 013-507-404-965-47X; 014-753-444-917-405; 014-891-029-572-599; 015-971-486-975-170; 016-325-303-690-114; 019-785-512-766-791; 023-311-760-249-072; 024-063-292-435-128; 024-758-193-391-079; 026-183-182-573-924; 034-743-116-883-222; 050-805-816-312-966; 063-706-062-314-030; 063-935-762-815-222; 064-400-499-357-900; 064-482-912-103-288; 073-459-058-614-53X; 074-810-301-573-785; 076-071-104-764-28X; 078-395-204-796-899; 080-118-387-618-96X; 083-485-296-851-583; 083-782-668-398-419; 085-001-502-383-40X; 086-358-182-749-22X; 089-888-753-187-062; 090-833-064-984-514; 092-868-978-532-023; 092-985-172-994-539; 096-457-879-682-324; 096-737-890-154-721; 098-040-332-404-119; 099-257-971-828-739; 105-057-884-940-537; 108-042-139-281-719; 108-847-558-296-497; 110-528-247-153-433; 116-339-119-777-116; 118-418-106-838-248; 123-218-689-488-554; 168-063-700-611-47X; 170-041-778-748-489; 198-123-839-918-134,1,false,, -154-990-499-905-722,Bibliometric study with statistical patterns of industry 4.0 applied to process control,2024-03-01,2024,journal article,Journal of Physics: Conference Series,17426588; 17426596,IOP Publishing,United Kingdom,K Cruzado-Yesquén; E Torres-Salazar; H Alvarez-Vasquez; J Saavedra-Ruíz; M Castañeda-Hipólito; S Gastiaburú-Morales; J Barandiarán-Gamarra; M Vásquez-Coronado; A Alviz-Meza,"Abstract; Industries are interested in offering their products or services to the consumer using high standards in process control. Industry 4.0 has emerged as a series of technological tools that can be incorporated into various processes. This research aims to perform a bibliometric analysis of the application of Industry 4.0 in process control in different sectors from 2013 to 2022 through the Scopus and Web of Science databases. The data studied were extracted from the bibliographic information of citations, abstracts, and keywords published by the articles collected. These data were processed in RStudio. As a result, it was found that the most cited articles are deep and automatic learning. Both technologies aim to reduce anomalies, increasing product efficiency, reliability, and quality. The contribution of physics in this work is shown in data mining tools, such as Bibliometrix, whose foundation is given by mathematical and statistical models, to extract data useful for future scientific studies.",2726,1,12008,012008,Statistical process control; Process (computing); Computer science; Control (management); Data science; Manufacturing engineering; Statistics; Engineering; Mathematics; Artificial intelligence; Operating system,,,,,https://iopscience.iop.org/article/10.1088/1742-6596/2726/1/012008/pdf https://doi.org/10.1088/1742-6596/2726/1/012008,http://dx.doi.org/10.1088/1742-6596/2726/1/012008,,10.1088/1742-6596/2726/1/012008,,,0,005-877-473-236-463; 012-583-157-370-118; 013-507-404-965-47X; 014-126-512-692-613; 014-700-547-161-357; 016-634-682-774-025; 025-038-829-409-205; 026-210-626-166-889; 026-634-085-441-401; 033-903-501-506-283; 034-519-495-322-081; 046-992-864-415-70X; 066-512-425-076-486; 068-680-960-546-270; 069-301-016-374-174; 073-775-823-470-313; 089-697-798-261-252; 099-348-746-991-517; 102-088-531-243-659; 128-201-504-791-76X; 140-148-211-949-003; 151-955-996-294-181; 159-404-787-952-686,0,true,,gold -155-159-875-725-764,A bibliometric analysis of the Global Reporting Initiative (GRI): global trends in developed and developing countries.,2023-02-09,2023,journal article,"Environment, development and sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Benoit Mougenot; Jean-Pierre Doussoulin,"The growing concern about climate change necessitates the development of models for long-term measurements of the sustainability performance. The Global Reporting Initiative suggests a framework for sustainability reporting. This study intends to fill two gaps in the existing literature. On the one hand, it assesses the Global Reports Initiative's impact on academics. This article, on the other hand, will compare public policies aimed at a Global Reporting Initiative in rich and developing countries from 1999 to 2020. The above research utilizes bibliometric analysis via Biblioshiny and the Scopus publications database, as well as an online interface for Bibliometrix analysis. For studying the Global Reports Initiative literature, this method offers a viable alternative to traditional bibliometric analysis. This is one of the first studies to use a computer approach to examine the literary paths of the Global Reporting Initiative issue. Among the findings we can mention that, the most GRI inquiries were distributed by the ""Journal of Cleaner Production."" The most useful GRI creators are Clarkson PM., Azapagic A., and Milne MJ. The findings of this paper suggest that the composition of the GRI addresses one of the keys to global monetary advancement, particularly in developing countries, for the foreseeable future. Our paper indicates that the Global Reporting Initiative principles have a strong potential to handle these connected issues in managing and maintaining the environment by adapting developed-country experiences to developing-country challenges.",26,3,1,6560,Scopus; Sustainability; Developing country; Sustainable development; Sustainability reporting; Bibliometrics; Political science; Business; Content analysis; Accounting; Computer science; Public relations; Corporate social responsibility; Library science; Economic growth; Economics; Sociology; MEDLINE; Social science; Ecology; Law; Biology,Bibliometric analysis; Global Reporting Initiative; Sustainability,,,,https://link.springer.com/content/pdf/10.1007/s10668-023-02974-y.pdf https://doi.org/10.1007/s10668-023-02974-y,http://dx.doi.org/10.1007/s10668-023-02974-y,36788933,10.1007/s10668-023-02974-y,,PMC9910778,0,000-624-400-916-479; 000-848-264-004-813; 004-566-959-830-388; 006-857-378-605-126; 012-346-256-087-044; 013-039-061-943-484; 013-507-404-965-47X; 018-025-399-192-993; 018-889-861-644-805; 028-037-650-718-395; 029-002-340-356-778; 029-089-402-918-815; 029-889-459-722-093; 030-273-117-055-833; 031-132-049-399-550; 031-903-224-926-833; 033-054-952-720-293; 040-004-492-794-774; 041-367-690-203-524; 045-465-367-752-050; 051-916-149-441-358; 053-704-864-850-335; 053-769-473-632-821; 057-069-173-037-463; 057-738-956-859-282; 059-184-995-005-31X; 061-854-748-828-564; 065-598-540-086-392; 065-691-955-481-884; 068-692-186-802-041; 072-204-462-210-974; 072-921-336-254-652; 073-169-146-264-853; 073-792-416-479-745; 076-011-632-310-164; 076-563-248-991-757; 079-740-823-732-211; 080-377-374-781-350; 085-881-342-872-359; 088-664-969-096-638; 090-592-555-205-111; 092-643-424-517-537; 097-225-842-710-460; 100-485-226-811-011; 101-281-021-236-377; 101-810-305-818-353; 106-470-709-719-654; 107-680-694-928-913; 111-999-385-285-79X; 112-381-620-675-459; 120-138-847-094-325; 124-402-087-990-21X; 130-261-008-190-443; 132-009-159-825-328; 133-919-646-071-753; 136-248-158-989-113; 136-753-368-875-170; 138-909-757-185-115; 147-207-431-130-958; 148-038-740-768-244,23,true,,bronze -155-466-044-620-910,Application of Trichoderma species increases plant salinity resistance: a bibliometric analysis and a meta-analysis,2023-05-30,2023,journal article,Journal of Soils and Sediments,14390108; 16147480,Springer Science and Business Media LLC,Germany,Li Cheng; Zhihong Xu; Xiaoqi Zhou,,23,7,2641,2653,Trichoderma; Salinity; Inoculation; Soil salinity; Biology; Horticulture; Botany; Ecology,,,,National Natural Science Foundation of China; National Natural Science Foundation of China; East China Normal University Multifunctional Platform for Innovation,,http://dx.doi.org/10.1007/s11368-023-03557-0,,10.1007/s11368-023-03557-0,,,0,000-898-317-503-647; 009-826-294-205-94X; 010-955-639-028-00X; 013-852-936-421-833; 015-068-712-397-76X; 015-631-853-302-357; 016-729-674-222-337; 016-759-958-498-578; 017-829-419-935-182; 019-777-034-679-65X; 020-727-733-024-388; 027-730-641-074-590; 028-991-743-996-723; 029-706-760-694-971; 032-441-933-766-775; 035-594-835-564-009; 042-207-308-256-89X; 042-220-577-905-241; 042-884-662-222-682; 044-545-335-061-814; 046-476-086-979-566; 056-032-446-438-540; 058-699-037-267-507; 060-322-663-693-759; 062-069-226-934-717; 062-625-472-535-310; 062-823-811-911-278; 070-278-828-576-671; 070-860-590-327-053; 078-226-350-797-710; 081-321-380-600-521; 086-337-741-422-440; 088-432-825-522-56X; 096-020-793-177-923; 124-689-584-700-341; 126-109-009-123-540; 129-811-057-176-662; 130-509-615-069-422; 145-478-004-759-630; 148-524-612-183-640; 159-652-506-284-021; 161-438-341-438-516; 164-970-316-638-153; 173-249-621-050-156; 174-298-114-309-714,7,false,, -156-065-778-997-150,"Mapping the research landscape of oral appliances in obstructive sleep apnea: a bibliometric analysis of trends, influential publications, and emerging areas.",2025-03-31,2025,journal article,BDJ open,2056807x,Springer Science and Business Media LLC,England,Gowri Sivaramakrishnan; Kannan Sridharan,"Oral appliances (OAs) are widely used in the management of obstructive sleep apnea (OSA), yet a comprehensive understanding of the research landscape in this field is lacking. This study aims to map the global research trends, influential publications, leading researchers, and emerging areas of interest related to OAs for OSA.; Data were retrieved from the Scopus. The search included terms related to OSA and OA. Articles were screened using Rayyan software. VOS viewer™ and Bibliometrix were used for analysis. Data were visualized through network maps and graphs to identify key authors, research centers, countries, and keyword trends. Co-occurrence of keywords and citation patterns were assessed to understand the research dynamics.; Out of 1370 initially retrieved articles, 753 were selected for final analysis, revealing a marked increase in scientific output in recent years. The study identified approximately 2400 researchers, with notable work from Cistulli P.A., Vanderveken O.M., and Lowe A.A., who formed key clusters. Major research hubs included The University of British Columbia, The University of Sydney, and Royal North Shore Hospital. The USA and Japan led in citations and publications. Global collaboration patterns were evident, showing contributions from various countries. Keywords like ""obstructive sleep apnea,"" ""mandibular advancement device,"" and ""oral appliance"" were frequently used, while emerging trends highlighted gaps in research related to tongue retaining and hybrid appliances. The top 20 cited documents from 1995-2020 encompassed reviews, clinical practice guidelines, and randomized trials, with the ""Sleep"" journal being the most cited source.; This bibliometric analysis provides a detailed overview of the research landscape on OAs for OSA. The study highlights significant trends, influential researchers, and key research centers. It also identifies emerging areas of interest and research gaps, offering guidance for future research to enhance the clinical effectiveness and adoption of OA therapy for OSA.; © 2025. The Author(s).",11,1,31,,Scopus; Obstructive sleep apnea; Citation; Bibliometrics; Oral appliance; Grey literature; Medicine; Web of science; MEDLINE; Library science; Meta-analysis; Computer science; Political science; Pathology; Internal medicine; Law,,,,,,http://dx.doi.org/10.1038/s41405-025-00305-z,40164602,10.1038/s41405-025-00305-z,,PMC11958721,0,000-076-316-446-49X; 005-741-358-977-810; 010-451-532-183-30X; 013-507-404-965-47X; 026-168-394-642-922; 044-330-062-290-655; 048-677-151-466-550; 049-551-642-253-27X; 051-652-066-212-49X; 058-870-470-456-373; 065-297-092-609-196; 076-123-640-077-506; 078-861-009-836-045; 097-524-044-105-995; 104-810-694-352-946; 114-958-911-496-852; 141-502-771-451-049; 197-040-402-215-794,1,true,cc-by,gold -156-169-837-039-814,"Bibliometric Analysis of the Topic ""Research Data Repository""",,2024,journal article,Scientific and Technical Information Processing,01476882; 19348118,Allerton Press,United States,T. A. Kalyuzhnaya; M. A. Pleshakova,,51,4,340,350,Computer science; Data science; Information retrieval; Bibliometrics; World Wide Web,,,,,,http://dx.doi.org/10.3103/s0147688224700710,,10.3103/s0147688224700710,,,0,001-788-981-268-621; 013-507-404-965-47X; 022-488-711-414-729; 023-861-955-754-948; 029-830-419-670-501; 035-885-737-953-393; 064-308-867-552-303; 070-462-022-251-464; 082-103-495-516-742; 176-969-945-869-525; 194-698-551-911-656; 196-487-127-463-201,0,false,, -156-328-830-641-680,AI and Assistive Technologies for Persons with Disabilities - Worldwide Trends in the Scientific Production Using Bibliometrix R Tool,2023-11-30,2023,book chapter,Communications in Computer and Information Science,18650929; 18650937,Springer Nature Switzerland,Germany,Pravin Dange; Tausif Mistry; Shikha Mann,,,,24,43,Scopus; Commercialization; Metadata; Computer science; Consolidation (business); Data science; Emerging technologies; Psychology; Engineering ethics; Political science; Engineering; Business; Artificial intelligence; World Wide Web; MEDLINE; Accounting; Law,,,,,,http://dx.doi.org/10.1007/978-3-031-47997-7_3,,10.1007/978-3-031-47997-7_3,,,0,008-319-033-100-725; 009-837-836-415-022; 013-507-404-965-47X; 016-653-093-244-871; 023-022-138-400-261; 036-935-882-457-459; 040-558-863-497-045; 040-589-303-300-824; 041-510-978-751-991; 042-318-514-195-727; 047-134-478-431-993; 051-647-739-244-271; 055-069-593-800-960; 059-507-729-500-979; 076-938-534-923-091; 080-939-946-077-003; 081-295-126-738-529; 102-952-660-914-374; 104-195-911-501-281; 104-919-753-218-202; 116-264-445-211-915; 121-748-110-881-046; 125-389-679-693-860; 136-908-911-319-170; 139-446-773-438-846; 162-855-474-582-208; 170-975-539-196-102,5,false,, -156-502-514-985-87X,"Examining Sustainable Product Design Technology: a Comprehensive Exploration of Trends, Innovations, Challenges, and Future Horizons",2025-06-11,2025,journal article,Circular Economy and Sustainability,2730597x; 27305988,Springer Science and Business Media LLC,,Ahmed M. Moustafa,,,,,,,,,,,,http://dx.doi.org/10.1007/s43615-025-00591-7,,10.1007/s43615-025-00591-7,,,0,005-659-178-330-494; 005-950-727-317-481; 007-168-229-860-628; 008-991-776-721-333; 009-002-693-250-279; 009-068-005-552-129; 010-076-053-338-579; 010-611-392-890-060; 010-756-175-343-412; 011-496-986-516-40X; 012-295-156-235-663; 012-470-775-677-730; 013-541-969-076-695; 013-596-882-149-255; 014-499-092-391-014; 016-480-734-667-32X; 016-533-017-913-619; 016-592-366-052-511; 016-612-756-738-303; 017-295-429-481-985; 017-723-032-334-993; 019-891-969-858-089; 020-424-846-075-407; 020-595-470-769-895; 020-763-309-256-401; 025-456-336-618-879; 026-469-377-926-949; 027-154-183-904-469; 027-515-990-129-121; 027-649-276-599-031; 027-772-003-754-124; 027-975-200-378-607; 028-598-326-858-169; 030-196-997-345-567; 030-587-229-346-215; 031-190-479-460-564; 033-698-753-407-361; 034-754-448-653-603; 035-787-424-936-331; 038-284-034-161-109; 038-352-719-099-645; 039-191-858-727-447; 039-415-392-173-154; 040-637-811-266-793; 041-516-774-299-355; 041-903-797-935-422; 041-980-606-435-003; 045-424-912-447-529; 046-242-734-829-071; 046-593-306-869-565; 047-278-047-100-511; 048-488-314-885-176; 051-178-428-271-070; 054-103-384-666-494; 054-159-894-171-769; 055-691-012-765-088; 056-394-212-972-095; 058-583-545-071-987; 059-038-327-622-923; 059-391-206-266-050; 059-760-283-319-890; 060-696-093-645-734; 061-848-600-754-991; 066-892-731-307-294; 070-238-085-964-692; 073-111-260-039-64X; 073-522-002-105-794; 076-706-090-505-40X; 078-251-507-825-682; 080-121-963-573-761; 080-194-313-033-12X; 081-472-568-736-971; 082-932-398-063-399; 087-341-915-014-403; 090-630-976-710-065; 093-515-960-734-535; 095-096-161-740-778; 095-570-923-799-203; 097-478-712-720-981; 099-810-620-473-21X; 100-417-661-499-419; 103-048-312-434-076; 108-337-287-967-18X; 110-725-530-458-091; 111-516-619-374-324; 113-235-259-991-522; 114-183-919-154-506; 115-520-560-495-208; 117-324-913-171-423; 118-315-654-841-69X; 120-727-658-577-34X; 121-466-524-718-649; 122-694-663-345-679; 130-662-042-317-353; 135-163-723-932-656; 138-625-571-558-716; 140-266-563-999-191; 140-605-423-957-559; 141-200-607-894-303; 143-039-416-227-342; 147-239-737-861-83X; 150-376-983-972-008; 155-182-885-430-076; 157-677-467-045-340; 162-037-634-091-551; 164-069-871-447-370; 174-845-894-659-968; 180-805-759-935-254; 193-272-490-109-779; 193-946-461-032-459; 198-607-352-959-947,0,false,, -156-743-394-145-805,Trends and features of autism spectrum disorder research using artificial intelligence techniques: a bibliometric approach,2022-12-21,2022,journal article,Current Psychology,10461310; 19364733,Springer Science and Business Media LLC,United States,Ibrahim Zamit; Ibrahim Hussein Musa; Limin Jiang; Wei Yanjie; Jijun Tang,,42,35,31317,31332,Psychology; Autism spectrum disorder; Artificial intelligence; Cognitive psychology; Autism; Developmental psychology; Computer science,,,,ANSO Scholarship for Young Talents; National Natural Science Foundation of China; National Natural Science Foundation of China; Shenzhen KQTD Project; Strategic Priority CAS Project; National Key Research and Development Program of China; National Science Foundation of China under grant; National Natural Youth Science Foundation of China; Shenzhen Basic Research Fund; Shenzhen Basic Research Fund; CAS Key Lab,,http://dx.doi.org/10.1007/s12144-022-03977-0,,10.1007/s12144-022-03977-0,,,0,000-452-908-115-500; 000-781-717-951-925; 001-948-371-333-799; 001-973-145-496-404; 002-052-422-936-00X; 003-070-043-879-063; 004-446-226-001-068; 005-160-447-118-692; 006-124-312-353-378; 006-260-116-705-520; 010-080-562-486-432; 011-302-191-774-204; 011-308-319-218-694; 011-888-887-597-411; 011-964-688-119-283; 012-038-412-072-684; 013-507-404-965-47X; 013-883-279-749-071; 014-651-555-125-390; 014-723-110-809-116; 016-269-848-088-621; 016-576-402-577-869; 017-643-910-001-51X; 017-750-600-412-958; 022-447-560-446-596; 022-961-170-375-333; 028-153-066-394-932; 028-251-813-488-940; 028-696-653-010-949; 029-502-544-840-503; 030-193-196-964-874; 032-804-778-814-369; 033-247-233-006-350; 035-041-445-821-006; 035-805-070-441-310; 036-028-720-617-780; 037-463-125-695-816; 041-149-997-739-600; 045-422-273-148-899; 047-203-003-219-952; 048-296-092-851-344; 050-844-942-890-726; 057-742-632-180-021; 059-556-004-978-132; 059-923-199-605-572; 061-451-759-153-519; 062-247-787-610-834; 070-045-748-497-888; 080-118-387-618-96X; 084-023-314-394-946; 084-289-078-709-894; 084-296-717-156-065; 087-878-180-639-444; 092-511-989-047-021; 093-530-739-304-785; 095-074-630-742-075; 099-267-066-668-201; 100-251-899-808-878; 101-201-232-713-249; 101-752-490-869-458; 121-707-574-802-675; 131-423-542-523-282; 136-721-370-666-89X; 143-817-036-925-200; 150-186-153-182-915; 158-445-877-603-88X; 194-739-135-241-524,4,false,, -156-901-491-322-472,Global research trends of MicroRNAs in rheumatoid arthritis: bibliometrics and visualization analysis.,2024-11-28,2024,journal article,Clinical rheumatology,14349949; 07703198,Springer Science and Business Media LLC,Germany,Xue Pang; Fengxia Xu; Chang Fan; Hui Jiang,,44,1,53,66,Bibliometrics; Medicine; China; Rheumatoid arthritis; Citation analysis; Web of science; Citation; Library science; Political science; Pathology; Internal medicine; Computer science; Meta-analysis; Law,Bibliometrics; Hotspots; MicroRNA; Rheumatoid arthritis; Visualization,"Arthritis, Rheumatoid/genetics; MicroRNAs/genetics; Bibliometrics; Humans; Biomedical Research/trends",MicroRNAs,Natural Science Foundation of Anhui Province (2208085MH276),,http://dx.doi.org/10.1007/s10067-024-07250-6,39604743,10.1007/s10067-024-07250-6,,,0,001-447-659-755-047; 002-052-422-936-00X; 005-094-227-577-536; 005-362-553-393-490; 007-324-393-010-088; 011-180-365-079-736; 012-818-586-869-973; 013-035-805-706-206; 013-507-404-965-47X; 018-626-975-546-440; 021-014-497-659-248; 022-577-325-685-912; 024-164-509-411-948; 026-784-465-080-410; 030-283-976-207-486; 033-444-817-005-389; 038-524-294-317-261; 041-379-881-767-945; 043-756-335-010-906; 047-673-093-177-210; 050-286-919-101-203; 051-708-913-198-941; 059-162-814-903-069; 059-395-305-303-660; 065-356-307-344-189; 078-692-685-600-471; 080-894-151-874-66X; 088-465-499-401-244; 092-755-561-083-524; 093-850-132-457-69X; 097-060-725-994-588; 107-993-350-850-89X; 114-183-572-692-777; 121-262-400-903-282; 128-730-509-514-618; 188-359-627-363-999,0,false,, -156-951-946-388-650,Non-genetic inheritance of environmental exposures: a protocol for a map of systematic reviews with bibliometric analysis,2021-11-06,2021,journal article,Environmental Evidence,20472382,Springer Science and Business Media LLC,United Kingdom,Erin L. Macartney; Szymon M. Drobniak; Shinichi Nakagawa; Malgorzata Lagisz,"Over the last few decades, we increasingly see examples of parental environmental experiences influencing offspring health and fitness. More recently, it has become clear that some non-genetic effects can be conferred across multiple generations. This topic has attracted research from a diversity of disciplines such as toxicology, biomedical sciences, and ecology, due to its importance for environmental and health issues, as well as ecological and evolutionary processes, with implications for environmental policies. The rapid accumulation of primary research has enabled researchers to perform systematic reviews (SRs), including meta-analyses, to investigate the generality of and sources of variation in non-genetic effects. However, different disciplines ask different questions and SRs can vary substantially in scope, quality, and terminology usage. This diversity in SRs makes it difficult to assess broad patterns of non-genetic effects across disciplines as well as determine common areas of interest and gaps in the literature. To clarify research patterns within the SR literature on non-genetic inheritance, we plan to create a map of systematic reviews as well as conduct bibliometric mapping (referred to as ‘research weaving’). We will address four key questions: first, what are the broad research patterns unifying the SR literature on non-genetic inheritance across disciplines? Second, are there discipline-specific research patterns, including terminology use, between disciplines? Third, how are authors of the SR literature connected? Fourth, what is the reliability of the SR literature? We will systematically collect reviews within the SR ‘family’ that examine non-genetic inheritance arising from parental and ancestral environment by searching databases for journal articles and grey literature, as well as conducting backwards and forwards searching. Search hits will be double screened using ‘decision trees’ that represent the inclusion criteria. All relevant data elements on the review’s topic, as well as a critical appraisal of the review’s approach and reporting, will be extracted into Excel flat sheets. Bibliometric data will be directly extracted from Scopus. We will then query all relevant data elements to address our objectives and present outcomes in easily interpretable tables and figures, accompanied by a narrative description of results.",10,1,1,11,Critical appraisal; Systematic review; Data science; Primary research; Generality; Inheritance (genetic algorithm); Ecology (disciplines); Computer science; Terminology; Grey literature,,,,Australian Research Council,https://environmentalevidencejournal.biomedcentral.com/articles/10.1186/s13750-021-00245-9,http://dx.doi.org/10.1186/s13750-021-00245-9,,10.1186/s13750-021-00245-9,3213995789,,0,000-044-678-726-986; 001-284-736-705-737; 002-580-562-402-404; 003-299-929-144-520; 006-093-167-928-892; 007-618-607-981-44X; 013-507-404-965-47X; 013-881-774-427-417; 015-028-455-170-137; 016-611-598-581-819; 022-901-099-853-800; 025-180-191-040-054; 025-617-137-216-345; 027-774-321-396-640; 029-549-361-744-998; 032-330-818-922-822; 032-337-545-447-457; 034-600-684-728-898; 036-212-765-312-26X; 038-077-401-681-770; 041-346-082-360-961; 042-105-639-409-320; 044-760-427-021-424; 047-052-262-174-036; 051-201-188-725-522; 058-870-470-456-373; 059-986-996-387-422; 067-236-152-749-355; 067-732-808-188-486; 068-746-000-731-048; 072-684-045-329-822; 080-375-789-188-808; 081-546-143-967-466; 086-434-561-042-162; 097-344-733-079-288; 105-282-956-706-039; 108-484-871-618-325; 110-738-005-258-481; 114-251-883-659-335; 135-960-176-715-194; 137-763-030-823-395; 141-562-203-874-638,2,true,"CC BY, CC0",gold -157-333-046-774-714,Global hotspots and trends of nutritional supplements in sport and exercise from 2000 to 2024: a bibliometric analysis.,2024-09-12,2024,journal article,"Journal of health, population, and nutrition",20721315; 16060997,Springer Science and Business Media LLC,Bangladesh,Te Fu; Haitao Liu; Chaofan Shi; Haichang Zhao; Feiyue Liu; Yingjian Xia,"Nutritional supplements for sports and exercise (NSSE) can facilitate the exogenous replenishment of the body. This study provides the first extensive overview of NSSE research through bibliometric and visual analyses.; We searched the Web of Science Core Collection database for literature related to ""NSSE"" from 1st January 2000 to 8th March 2024. A total of 1744 articles were included. CiteSpace, VOSviewer, and Bibliometrix R package software were used to analyze the data.; Research in the NSSE can be divided into steady growth, exponential growth, fluctuating stage, and surge stages. The United States is the most active country in this field. In recent years, the leading countries have been Croatia, Colombia, Slovenia, Chile, Egypt, China, and Thailand. The Australian Institute of Sports is the top research institution in terms of number of publications. Burke, LM from Australia published the most articles. Research in this area has primarily been published in Nutrients in Switzerland. The study population mainly consisted of men, and postmenopausal women were the main focus of the female group. Coronary heart and cardiovascular diseases continue to dominate research.; Research on the NSSE is developing rapidly, with an annual growth trend. Insulin resistance, sports nutrition, inflammation, alpha-linolenic acid, limb strength performance, female sex, and gut microbiota are the focus of the current research and trends for future research. Future research should focus on improving the scientific training system for athletes and quality of training and life for the general public.; © 2024. The Author(s).",43,1,146,,Environmental health; Medicine; Epidemiology; Geography; Gerontology; Internal medicine,Bibliometric analysis; Dietary supplements; Exercise; Nutritional supplements; Sport,Humans; Dietary Supplements; Bibliometrics; Exercise; Sports/statistics & numerical data; Male; Female; Global Health; Chile; Colombia; Sports Nutritional Physiological Phenomena; Croatia; Thailand,,Training Program for Young Core Teachers in Higher Education Institutions of Henan Province (2023GGJS023); Education and Teaching Reform Project in Higher Education of Henan Province (2024SJGLX0265); Henan University Graduate Education and Teaching Reform Project (YJSJG2023XJ062); Henan University Graduate Education Innovation and Quality Improvement Plan Project (SYLAL2022011),,http://dx.doi.org/10.1186/s41043-024-00638-9,39267150,10.1186/s41043-024-00638-9,,PMC11397053,0,000-347-824-642-464; 001-719-026-803-199; 001-866-915-699-213; 002-052-422-936-00X; 003-050-312-524-511; 004-601-512-300-963; 005-699-134-742-020; 007-940-695-828-028; 008-363-043-697-199; 010-287-037-165-284; 011-985-128-133-485; 012-970-314-086-162; 013-507-404-965-47X; 014-543-536-074-630; 016-504-164-169-807; 018-873-743-486-360; 019-991-168-523-770; 020-707-160-664-186; 023-270-586-625-520; 023-620-543-445-199; 025-836-538-858-576; 030-195-346-345-868; 030-268-170-746-071; 030-273-933-952-380; 031-391-630-228-09X; 031-859-475-573-563; 031-971-967-247-916; 032-907-972-381-28X; 034-749-426-044-536; 037-021-305-408-310; 037-151-209-789-323; 043-365-918-859-911; 044-257-767-190-568; 044-675-684-492-298; 045-021-778-560-929; 046-897-486-712-33X; 046-911-258-218-813; 049-391-379-302-694; 049-985-518-863-431; 052-564-531-798-147; 053-138-919-977-162; 053-929-154-801-878; 054-988-670-644-81X; 055-112-753-506-682; 055-224-874-283-434; 056-503-513-423-882; 058-010-147-990-058; 058-869-297-770-968; 059-103-032-610-667; 059-626-588-162-727; 061-054-902-409-451; 063-048-555-120-478; 063-251-143-607-080; 064-400-499-357-900; 065-474-353-475-54X; 065-700-701-232-783; 066-853-704-371-90X; 069-594-196-553-699; 069-617-176-955-972; 071-241-618-023-988; 072-006-101-755-656; 075-160-693-424-758; 076-838-194-341-686; 077-580-395-930-429; 080-757-469-106-774; 080-977-108-232-315; 084-356-657-850-312; 084-608-760-012-702; 087-563-825-110-702; 090-145-233-615-164; 091-089-949-884-397; 091-452-578-437-419; 094-523-422-279-498; 095-183-005-328-234; 096-300-708-080-024; 096-606-080-247-715; 096-934-047-610-810; 098-356-710-892-393; 098-730-941-070-466; 099-825-765-676-159; 103-607-451-256-634; 105-905-671-485-066; 107-278-316-901-590; 110-453-603-959-748; 111-107-281-366-732; 112-103-591-365-119; 114-058-296-947-186; 114-352-973-897-348; 116-315-948-769-096; 116-339-119-777-116; 117-057-629-217-910; 117-196-856-417-322; 118-466-122-656-803; 127-173-505-512-927; 137-844-138-495-690; 141-727-529-303-475; 142-851-052-813-332; 145-544-063-046-887; 166-426-431-694-779; 184-419-073-070-188,5,true,"CC BY, CC0",gold -157-437-815-047-99X,Urban carrying capacity bibligraphy,2019-01-01,2019,dataset,Figshare,,,,Gulzhan Aizholova,"File contains ""r bibliometrix"" library documentation code for R software (source: Aria, M. & Cuccurullo, C. (2017) bibliometrix: An R-tool for comprehensive science mapping analysis, Journal of Informetrics, 11(4), pp 959-975, Elsevier/ https://github.com/massimoaria/bibliometrix) for bibligraphy analysis of Urban carrying capacity related researches and Web of Science data records. In total 309 data record of Web of Science database was extracted and cleaned (n=309).",,,,,Carrying capacity; Environmental science; Business; Biology; Ecology,,,,,https://figshare.com/articles/Urban_carrying_capacity_bibligraphy/7569602,http://dx.doi.org/10.6084/m9.figshare.7569602,,10.6084/m9.figshare.7569602,,,0,,0,true,cc-by,gold -157-455-072-675-23X,A bibliometric analysis of published research employing musculoskeletal imaging modalities to evaluate foot osteoarthritis.,2022-05-20,2022,journal article,Journal of foot and ankle research,17571146,Wiley,United Kingdom,Prue Molyneux; Sarah Stewart; Catherine Bowen; Richard Ellis; Keith Rome; Matthew Carroll,"Temporal and global changes in research utilising imaging to assess foot osteoarthritis is currently unknown. This study aimed to undertake a bibliometric analysis of published research to: (1) identify the imaging modalities that have been used to evaluate foot osteoarthritis; (2) explore the temporal changes and global differences in the use of these imaging modalities; and (3) to evaluate performance related to publication- and citation-based metrics.; A literature search was conducted using Scopus to identify studies which had used imaging to assess foot osteoarthritis. Extracted data included publication year, imaging modality, citations, affiliations, and author collaboration networks. Temporal trends in the use of each imaging modality were analysed. Performance analysis and science mapping were used to analyse citations and collaboration networks.; 158 studies were identified between 1980 and 2021. Plain radiography was the most widely used modality, followed by computed tomography, magnetic resonance imaging (MRI) and ultrasound imaging (USI), respectively. The number of published studies increased over time for each imaging modality (all P ≥ 0.018). The most productive country was the United States of America (USA), followed by the United Kingdom and Australia. International authorship collaboration was evident in 57 (36.1%) studies. The average citation rate was 23.4 per study, with an average annual citation rate of 2.1.; Published research employing imaging to assess foot osteoarthritis has increased substantially over the past four decades. Although plain radiography remains the gold standard modality, the emergence of MRI and USI in the past two decades continues to advance knowledge and progress research in this field.; © 2022. The Author(s).",15,1,39,,Medicine; Modalities; Modality (human–computer interaction); Magnetic resonance imaging; Medical physics; Osteoarthritis; Foot (prosody); Citation; Radiology; Neuroradiology; Artificial intelligence; Pathology; Computer science; Library science; Alternative medicine; Social science; Linguistics; Philosophy; Neurology; Psychiatry; Sociology,Foot osteoarthritis; Imaging modalities,"Bibliometrics; Humans; Magnetic Resonance Imaging; Osteoarthritis/diagnostic imaging; Radiography; Tomography, X-Ray Computed; United States",,Health Research Council of New Zealand (21/025),https://jfootankleres.biomedcentral.com/track/pdf/10.1186/s13047-022-00549-0 https://doi.org/10.1186/s13047-022-00549-0 https://openrepository.aut.ac.nz/bitstreams/53f48eb8-7fd4-4911-9aa6-29926028ab94/download http://hdl.handle.net/10292/15149 https://eprints.soton.ac.uk/467935/2/s13047_022_00549_0.pdf,http://dx.doi.org/10.1186/s13047-022-00549-0,35596206,10.1186/s13047-022-00549-0,,PMC9121542,0,002-356-916-032-871; 003-321-167-084-071; 007-408-111-717-279; 008-847-276-391-386; 009-128-509-498-113; 009-335-266-284-867; 011-245-007-230-71X; 014-451-051-025-752; 014-884-987-182-29X; 015-751-342-999-881; 016-217-276-643-284; 019-875-139-059-405; 022-743-999-788-177; 025-927-400-594-807; 028-800-911-277-740; 028-996-050-421-807; 029-142-465-812-209; 031-165-217-045-93X; 031-892-461-565-727; 032-966-491-654-160; 034-768-446-226-023; 036-179-220-961-399; 037-091-629-389-439; 039-905-154-241-782; 040-012-057-111-369; 040-088-516-895-133; 046-893-167-334-37X; 046-992-864-415-70X; 050-054-211-481-885; 050-165-106-478-336; 051-259-308-716-682; 053-989-614-139-93X; 056-747-691-895-816; 065-791-506-035-254; 071-134-475-176-739; 071-878-836-294-733; 073-442-990-951-362; 076-077-298-515-667; 076-242-676-388-308; 089-241-293-864-917; 097-166-552-521-138; 100-232-873-679-306; 108-865-487-755-957; 109-241-622-865-712; 111-077-946-447-955; 112-640-353-590-20X; 125-545-654-783-044; 130-057-480-639-007; 132-723-851-457-646; 145-858-475-511-118; 156-039-231-084-658; 195-930-224-563-148,6,true,cc-by,gold -157-489-988-569-870,Psychological adaptation of international students in higher education: a bibliometric analysis,2025-05-10,2025,journal article,Current Psychology,10461310; 19364733,Springer Science and Business Media LLC,United States,Fariba Soheili; Margherita Lanz,"Abstract; This study conducts a bibliometric analysis of research on the psychological adaptation of international students (PAIS) in higher education. As the number of international students continues to grow worldwide, understanding their psychological adaptation is crucial for enhancing their academic and social experience. This study analyzes academic publications indexed in Scopus from 1986 to 2024 using Bibliometrix and VOSviewer. The analysis identifies leading authors, countries, and journals in the field of PAIS. A key finding reveals a moderate annual growth rate of 4.71% in publications, with the USA leading in research output. Prominent themes include psychological adjustment, acculturation, and social support. Emerging trends highlight the increasing focus on psychological support, identity, and mental health. This study offers a comprehensive overview of the PAIS research landscape, providing valuable insights for scholars and practitioners aiming to support the psychological adaptation of international students.",44,11,10670,10678,Psychology; Adaptation (eye); Psychological science; Applied psychology; Mathematics education; Social psychology; Neuroscience,,,,Università Cattolica del Sacro Cuore,,http://dx.doi.org/10.1007/s12144-025-07926-5,,10.1007/s12144-025-07926-5,,,0,000-279-995-166-528; 000-667-231-896-402; 006-423-021-338-442; 008-792-812-034-564; 013-507-404-965-47X; 014-489-145-949-132; 015-468-340-922-254; 019-128-299-119-244; 022-999-713-375-617; 032-190-532-775-722; 043-271-376-152-358; 043-863-954-669-930; 044-808-566-509-681; 046-992-864-415-70X; 050-609-067-982-963; 051-083-375-798-335; 058-369-253-384-490; 065-010-405-236-060; 068-782-816-469-220; 087-821-652-637-432; 091-449-861-235-401; 098-648-038-105-666; 106-146-900-007-327; 107-990-996-566-202; 125-795-903-399-740; 135-801-632-218-493; 138-786-487-889-085; 143-262-475-245-26X; 143-325-857-855-720; 144-083-294-584-070; 144-528-895-151-421; 157-305-533-222-505; 178-070-402-140-284; 189-317-968-351-479,0,true,cc-by,hybrid -157-734-509-145-971,Developmental trends and knowledge frameworks in the application of radiomics in prostate cancer: a bibliometric analysis from 2000 to 2024.,2024-12-18,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Pan Hao; Ruiqiang Xin; Yancui Li; Xu Na; Xiaoyong Lv,"This research utilized the bibliometrics method to analyze the published literature related to prostate cancer (PCa) imaging. Furthermore, current knowledge and research hotspots of radiomics in PCa diagnosis and treatment were comprehensively reviewed, as well as progress and emerging trends in field were explored.; In this investigation, the relevant literature on radiomics, and PCa was retrieved from Web of Science Core Collection (WoSCC) databases from 2000 and 2024. Furthermore, a comprehensive bibliometric analysis was carried out using advanced tools like CiteSpace6.2, VOS viewer, and the 'bibliometrix' package of R software to visualize the annual distribution of publications across various aspects such as authors, countries, journals, institutions, and keywords.; This analysis included 593 from 58 countries including China and the United States. Chinese Academy of Sciences and Frontiers in Oncology were the institutions and journals that publish the most relevant articles, -while Radiology journal had the greatest number of co-cited publications. Furthermore, 3,621 authors published on this topic, of which Madabhushi Anant and Stoyanova Radka had the highest contributions. Moreover, Lambin, P. had the most co-citations. In addition, the diagnostic characteristics of radiomics in PCa imaging and treatment strategies are the current research focal points. The establishment of multi-functional imaging techniques and independent factor models warrants future investigation.; In summary, this analysis revealed that the research on PCa imaging is developing vigorously, focusing on the diagnostic methods and intervention measures of imaging in PCa diagnosis and treatment. In the future, there is an urgent need for improved collaboration and communication among countries and institutions.; © 2024. The Author(s).",15,1,781,,Radiomics; Bibliometrics; Impact factor; Medical physics; Publication; Prostate cancer; Medicine; Data science; Computer science; Library science; Cancer; Political science; Radiology; Internal medicine; Law,Bibliometric; Cite space; Prostate cancer; Radiomics,,,,,http://dx.doi.org/10.1007/s12672-024-01678-7,39692833,10.1007/s12672-024-01678-7,,PMC11655755,0,003-623-930-797-459; 004-057-437-787-823; 004-373-803-902-09X; 004-985-934-186-414; 007-500-155-247-91X; 007-878-332-790-572; 008-100-346-963-525; 010-094-484-015-308; 013-930-961-455-833; 015-311-540-903-239; 015-983-774-483-101; 021-794-696-450-391; 025-609-597-854-698; 026-202-567-967-685; 031-807-062-440-880; 033-599-333-093-040; 034-221-165-673-741; 038-055-229-803-205; 038-875-171-796-578; 040-691-280-312-996; 041-488-159-216-970; 043-561-382-762-06X; 054-810-150-647-787; 064-400-499-357-900; 069-539-034-847-713; 079-710-342-138-417; 086-044-449-381-531; 087-162-053-403-128; 092-429-030-442-934; 102-193-379-614-260; 104-107-681-941-341; 108-092-245-539-600; 118-837-569-914-194; 121-703-753-041-703; 128-631-414-607-308; 133-168-358-895-817; 138-701-892-211-280; 141-770-516-078-794; 142-754-931-646-337; 145-113-380-137-745; 146-595-979-046-779; 167-373-519-239-682,1,true,cc-by,gold -157-775-388-975-901,Non-coding RNAs as modulators of radioresponse in triple-negative breast cancer: a systematic review.,2024-10-02,2024,journal article,Journal of biomedical science,14230127; 10217770,Springer Science and Business Media LLC,Switzerland,Maria Vitoria Tofolo; Fernanda Costa Brandão Berti; Emanuelle Nunes-Souza; Mayara Oliveira Ruthes; Lucas Freitas Berti; Aline Simoneti Fonseca; Daiane Rosolen; Luciane Regina Cavalli,"Triple-negative breast cancer (TNBC), characterized by high invasiveness, is associated with poor prognosis and elevated mortality rates. Despite the development of effective therapeutic targets for TNBC, systemic chemotherapy and radiotherapy (RdT) remain prevalent treatment modalities. One notable challenge of RdT is the acquisition of radioresistance, which poses a significant obstacle in achieving optimal treatment response. Compelling evidence implicates non-coding RNAs (ncRNAs), gene expression regulators, in the development of radioresistance. This systematic review focuses on describing the role, association, and/or involvement of ncRNAs in modulating radioresponse in TNBC. In adhrence to the PRISMA guidelines, an extensive and comprehensive search was conducted across four databases using carefully selected entry terms. Following the evaluation of the studies based on predefined inclusion and exclusion criteria, a refined selection of 37 original research articles published up to October 2023 was obtained. In total, 33 different ncRNAs, including lncRNAs, miRNAs, and circRNAs, were identified to be associated with radiation response impacting diverse molecular mechanisms, primarily the regulation of cell death and DNA damage repair. The findings highlighted in this review demonstrate the critical roles and the intricate network of ncRNAs that significantly modulates TNBC's responsiveness to radiation. The understanding of these underlying mechanisms offers potential for the early identification of non-responders and patients prone to radioresistance during RdT, ultimately improving TNBC survival outcomes.",31,1,93,,Radioresistance; Triple-negative breast cancer; Breast cancer; Radiation therapy; microRNA; Biology; Bioinformatics; Cancer research; Oncology; Cancer; Medicine; Computational biology; Internal medicine; Gene; Genetics,Non-coding RNAs; Radiation; Radioresponse; Radiotherapy; Triple-negative breast cancer,"Female; Humans; Radiation Tolerance/genetics; RNA, Untranslated/genetics; Triple Negative Breast Neoplasms/genetics","RNA, Untranslated",,,http://dx.doi.org/10.1186/s12929-024-01081-y,39354523,10.1186/s12929-024-01081-y,,PMC11445946,0,000-215-432-883-950; 000-423-278-704-198; 000-461-906-874-25X; 002-167-481-561-068; 002-485-696-711-311; 003-045-683-566-917; 007-746-396-620-949; 008-467-607-853-529; 008-580-299-054-155; 009-482-112-722-107; 009-823-857-367-026; 010-396-101-763-805; 012-890-338-902-574; 013-242-937-842-906; 013-407-641-662-933; 013-507-404-965-47X; 014-849-096-722-025; 015-943-521-773-876; 016-219-928-195-333; 016-978-866-630-834; 017-107-808-304-398; 017-300-737-144-757; 018-036-729-980-487; 018-267-764-312-132; 019-646-209-742-746; 020-726-765-622-185; 023-427-950-931-616; 023-692-549-037-500; 026-150-388-710-786; 026-184-641-560-124; 026-336-495-743-87X; 028-866-949-327-127; 031-907-923-009-661; 034-500-219-047-319; 034-646-181-131-575; 036-257-369-850-954; 036-883-674-358-69X; 039-829-536-295-119; 040-101-169-908-369; 040-920-295-859-86X; 041-330-169-233-897; 042-803-272-858-047; 043-307-825-848-847; 044-204-326-917-822; 045-748-451-919-490; 046-125-885-078-751; 053-056-660-103-511; 054-543-224-861-644; 060-583-616-354-610; 061-011-374-868-24X; 063-636-162-732-204; 064-461-966-913-339; 065-010-405-236-060; 075-620-866-458-214; 075-867-456-444-068; 080-553-258-740-551; 080-683-216-109-396; 081-815-561-058-970; 083-275-795-865-394; 083-951-165-085-415; 089-688-126-578-201; 091-474-778-993-628; 092-156-510-798-533; 092-422-298-022-955; 102-488-129-224-516; 103-314-419-710-914; 107-483-302-885-238; 112-821-714-433-094; 116-737-006-013-930; 117-707-218-428-491; 131-971-135-461-122; 134-739-904-444-160; 155-568-929-771-107; 160-113-419-673-320; 160-670-847-284-665; 164-199-402-305-068; 172-124-876-559-821; 197-812-879-949-020,0,true,"CC BY, CC0",gold -157-824-243-794-200,Online marketing and brand awareness for HEI: A review and bibliometric analysis.,2024-05-13,2024,journal article,F1000Research,20461402,F1000 Research Ltd,United Kingdom,Sailaja Bohara; Vashali Bisht; Pradeep Suri; Diksha Panwar; Jyoti Sharma,"This study conducted a comprehensive bibliometric analysis to identify the gaps in the existing literature related to Online marketing and brand awareness strategies for HEI. It has evaluated the current state of the literature on the given topic showing the pivotal role of online marketing and brand awareness in higher education for enrollment.; The study used a web-based application, Biblioshiny, which comes in the bibliometrix package. The study used the Scopus database to create the data set, given its conventional construction and quality of the sources. The analysis done is descriptive. By using the bibliometrix software, the study showed the authors name, articles, sources, citations, relevant journals and co-citation from the year 2017 to 2022. The time period selected by the study was five years which means that articles published from 2017 to 2022 have been taken for the study.; We found that HEI online marketing and brand awareness have not been explored much as it has not reached the stage of maturity. Most of the publication was done during the time of Covid-19. Also, the role of brand awareness in student enrollment decisions for HEI requires more investigation. Top most publications their sources and top authors are identified.; Bibliometric analysis has provided valuable insights into the seminal work, emerging trends, and the gap in the study. This area of study has been explored but not as much as challenges, and the effectiveness of online marketing tools like seo, sem,ppc and more has not been measured. Further, this paper allows researchers to study by examining the pattern of publications by seeing the different authorships, co-authors, collaborations, relevant sources, and citations. The insights of this paper will help education policymakers devise more creative strategies to increase enrollment, ensuring sustained relevance and competitive advantage in higher education institutions .; Copyright: © 2024 Bohara S et al.",12,,76,76,Open peer review; Plant biology; Marketing; Medicine; Psychology; Business; Biology; Botany; Neuroscience,Bibliometrix; Brand awareness; Enrollment; Higher education institutions; Online marketing; Science mapping; Technology; analysis,Humans; Bibliometrics; COVID-19; Internet; Marketing; Pandemics,,No funding has been taken for this research,https://f1000research.com/articles/12-76/pdf https://doi.org/10.12688/f1000research.127026.2,http://dx.doi.org/10.12688/f1000research.127026.1,39931162,10.12688/f1000research.127026.1; 10.12688/f1000research.127026.2,,PMC11809636,0,003-724-971-585-818; 011-290-281-744-193; 012-498-274-201-077; 013-324-113-861-417; 016-190-228-090-075; 016-755-124-367-848; 020-980-952-075-387; 025-083-616-260-737; 042-892-840-687-272; 043-542-111-876-854; 044-869-468-032-962; 045-809-456-807-996; 046-992-864-415-70X; 054-343-350-778-175; 060-958-011-242-657; 069-495-841-375-087; 072-835-204-148-689; 081-176-997-670-441; 085-300-287-100-525; 086-592-489-284-792; 090-606-948-169-54X; 098-913-296-346-58X; 104-151-927-001-666; 119-018-907-192-25X; 123-388-032-214-50X; 126-646-454-791-794; 141-302-242-630-109; 154-386-727-070-683; 157-824-243-794-200; 181-059-892-236-254,2,true,cc-by,gold -158-396-188-525-494,Discussão teórica sobre os conceitos de sustentabilidade no enoturismo através do bibliometrix,2022-08-09,2022,journal article,Revista Brasileira de Pesquisa em Turismo,19826125,ANPTUR - Associacao Nacional de Pesquisa e Pos Graducao em Turismo,,Jaiany Rocha Trindade; Kettrin Farias Bem Maracajá; Bruno Cicciú; Rômulo Benício Lucena Filho; Vander Valduga,"A sustentabilidade tem papel fundamental no turismo pois está presente nos fatores ambientais, econômicos e sociais, com destaque ao crescimento do turismo em vinícolas focado na preservação/conservação. A questão central da pesquisa é: qual é a realidade dos estudos científicos sobre e no turismo e sustentabilidade? Como objetivo, o trabalho visa analisar as pesquisas científicas que abordaram a temática do enoturismo e sustentabilidade. A metodologia é composta por um ensaio teórico qualitativo e descritivo feito por meio de pesquisa bibliográfica, com levantamento da produção científica disponível nas bases “WoS” e “Scopus”. A opção pelo termo de busca utilizado foram as palavras-chave ""wine tourism"" and ""sustainability"". Os resultados sugerem que as pesquisas sobre a sustentabilidade na cadeia do enoturismo estão crescendo com percepções emergentes e mostram uma concentração geográfica da pesquisa em alguns países como França, Estados Unidos e Brasil. Os consumidores estão se tornando mais sensibilizados sobre as consequências ambientais de suas escolhas, com uma maior atenção às questões sustentáveis na compra de produtos. Conclui-se que ainda existem poucos estudos direcionados para a sustentabilidade no enoturismo e que expliquem como a implantação de práticas de sustentabilidade contribui para o aumento da competitividade de empresas do setor vitivinícola.",16,,2644,2644,Tourism; Sustainability; Humanities; Geography; Political science; Business; Art; Ecology; Archaeology; Biology,,,,,https://rbtur.org.br/rbtur/article/download/2644/1538 https://doi.org/10.7784/rbtur.v16.2644,http://dx.doi.org/10.7784/rbtur.v16.2644,,10.7784/rbtur.v16.2644,,,0,,3,true,cc-by,gold -158-425-344-550-705,A Bibliometric Literature Review of Green Supply Chain Management and Its Impacts Using VOSviewer and R (Bibliometrix),,2023,journal article,Journal of Service Science and Management,19409893; 19409907,"Scientific Research Publishing, Inc.",,Christian Ayemoma Apolaagoa; Abdul-Razak Muhammed; Rakibu Suglo Zuzie; Abraham Owusu,"This article applies a bibliometric analysis approach to explore the concept of Green Supply Chain Management (GSCM) and its impacts using a relational technique on existing literature. It uses data sourced primarily from the Scopus database. A total of 652 documents by 1959 authors were retrieved based on narrowed search criteria to obtain relevant publications in the research area. Publications from 2017 to 2022 were used to conduct the analysis. The approach used both VOSviewer and bibliometrics for co-authorship, keyword co-occurrence, bibliographic coupling and co-citations to underscore the scientific evolution of the topic. The objective of the analysis is to identify predominant themes as well as emerging concepts related to the topic and to make significant theoretical contributions to the study area by providing future research directions. The result of the analysis highlights the main information, publication trends, impactful authors and sources, most cited documents, institutional productivity over time, co-authorship network, a three-fold plot of the evolution of the research field, bibliographic coupling, keyword co-occurrence and prominent relationships. These are visually represented in tables and strategic diagrams for easy analysis and understanding of the state of the art in GSCM research. The review is an effort to identify theoretical gaps, guide researchers and industry professionals in their research and operations within the field of management with emphasis on GSCM and coordinate research efforts across and among countries and authors respectively.",16,3,369,390,Bibliographic coupling; Bibliometrics; Scopus; Computer science; Field (mathematics); Supply chain management; Data science; Web of science; Productivity; Supply chain; Knowledge management; Management science; Citation; Business; Library science; Marketing; Political science; MEDLINE; Mathematics; Economics; Pure mathematics; Law; Macroeconomics,,,,,http://www.scirp.org/journal/PaperDownload.aspx?paperID=125975 https://doi.org/10.4236/jssm.2023.163021,http://dx.doi.org/10.4236/jssm.2023.163021,,10.4236/jssm.2023.163021,,,0,005-057-616-857-627; 007-030-829-402-768; 013-122-358-447-999; 016-520-213-625-574; 020-650-493-836-578; 023-471-372-885-491; 023-654-030-797-362; 031-374-350-479-113; 038-745-955-878-277; 041-072-151-736-972; 044-776-532-451-668; 046-864-077-133-619; 048-138-868-715-670; 050-262-699-036-57X; 050-529-794-451-376; 052-357-694-287-737; 060-779-257-891-725; 067-387-662-967-860; 068-348-198-363-629; 068-527-555-135-856; 078-591-234-329-261; 078-663-139-988-621; 085-724-093-867-882; 088-366-308-551-570; 088-444-176-914-632; 092-605-821-845-529; 093-578-643-029-072; 094-629-552-912-357; 101-819-169-880-486; 112-810-689-535-289; 114-070-132-931-438; 114-920-927-476-000; 125-090-928-615-251; 127-852-607-930-454; 146-118-783-422-427; 146-198-549-922-733; 192-145-315-234-785,1,true,,gold -158-615-303-372-778,Bibliometric Analysis and Network Visualization of Nanozymes for Microbial Theranostics in the Last Decade.,2024-12-03,2024,journal article,Applied biochemistry and biotechnology,15590291; 02732289,Springer Science and Business Media LLC,United States,Hamza Ettadili; Caner Vural,,197,3,1923,1945,China; Web of science; Prism; Nanotechnology; Computer science; Biotechnology; Biochemical engineering; Data science; Chemistry; Biology; Engineering; Geography; MEDLINE; Materials science; Physics; Biochemistry; Archaeology; Optics,Bibliometric; Diagnostic; Microorganisms; Nanozymes; Science mapping; Therapy,Bibliometrics; Theranostic Nanomedicine; Humans; Nanostructures/chemistry; Anti-Bacterial Agents/pharmacology,Anti-Bacterial Agents,,,http://dx.doi.org/10.1007/s12010-024-05120-0,39625609,10.1007/s12010-024-05120-0,,,0,000-390-807-544-348; 002-052-422-936-00X; 003-145-563-195-355; 003-355-980-888-756; 003-546-269-245-435; 003-593-673-963-828; 005-025-667-542-661; 005-287-875-541-858; 009-251-416-677-925; 013-390-356-908-801; 013-507-404-965-47X; 017-204-968-752-020; 018-072-584-705-692; 018-718-117-672-908; 019-790-195-768-502; 021-376-361-314-88X; 022-609-473-790-718; 024-216-803-065-590; 026-887-038-461-405; 033-880-497-304-38X; 034-973-660-364-155; 036-070-574-589-601; 037-706-496-676-917; 038-554-742-320-526; 039-712-505-079-959; 044-486-920-049-085; 044-822-176-352-704; 046-992-864-415-70X; 050-231-683-164-532; 050-289-224-250-37X; 053-594-779-403-421; 053-674-573-641-387; 055-677-470-245-943; 059-934-778-166-029; 060-822-646-860-464; 061-405-143-184-272; 063-270-198-764-60X; 063-548-488-347-226; 063-699-227-265-28X; 064-828-658-274-481; 071-247-285-864-523; 072-279-786-919-417; 074-826-903-819-232; 075-683-247-602-609; 076-820-557-788-60X; 078-381-836-683-49X; 083-981-924-194-653; 093-575-168-206-792; 094-882-234-721-538; 099-224-041-474-152; 102-599-629-583-779; 108-744-848-919-021; 108-967-999-549-820; 116-224-345-858-600; 117-650-813-937-472; 119-962-587-675-413; 119-981-074-528-024; 120-229-008-066-319; 125-320-381-243-87X; 126-811-197-243-346; 133-611-094-171-543; 135-346-738-230-915; 136-001-940-885-213; 141-666-218-886-363; 148-011-734-336-007; 151-536-545-559-228; 152-186-919-440-109; 153-292-322-957-434; 158-872-209-710-571; 167-251-598-383-600; 167-683-807-421-861; 170-229-653-622-246; 176-008-489-998-83X; 181-472-412-979-139; 183-965-201-279-966; 185-314-194-864-019; 188-351-332-321-736; 190-188-430-490-570; 193-109-529-207-182; 196-906-259-397-908,1,false,, -159-081-466-481-592,Inteligencia artificial en estudiantes universitarios. Una revisión bibliométrica,2024-01-19,2024,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Victor Manuel Valdiviezo Sir,"The purpose of this research was to examine the evolution, scope, and orientation of the scientific production on artificial intelligence applications in university students. The methodology, with a non-experimental design and qualitative approach, involved a search in Scopus, identifying 643 documents between 1975-2024, analyzed through VOSviewer and Bibliometrix. The results show an emerging field, but with rapid growth (4.59% per year), with notoriety of Kong, Abdulrahman and Chai. Research is predominantly in computer science (61%), social sciences (33%) and engineering (23%) from China, USA, Spain and Taiwan. Current applications focus on the use of AI in education, machine learning, support for academic decisions and student mental health. However, it is necessary to expand the approach towards ethical and regulatory aspects and the evaluation of multifaceted effects on different student profiles. In conclusion, although production is growing rapidly, more comprehensive perspectives are required to responsibly enhance the impact of these technologies on the university educational experience.",,,,,Psychology; Political science,,,,,https://zenodo.org/doi/10.5281/zenodo.10535521,http://dx.doi.org/10.5281/zenodo.10535521,,10.5281/zenodo.10535521,,,0,,0,false,, -159-392-490-913-656,"A bibliometric study on blockchain-based supply chain: a theme analysis, adopted methodologies, and future research agenda.",2022-12-26,2022,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Muhammad Shoaib; Shengzhong Zhang; Hassan Ali,"The emergence of the underlying blockchain technology of bitcoin has gained extensive attention from researchers and practitioners. As distributed ledger technology, blockchain widely finds its applications in the supply chain to mitigate issues related to transparency, information sharing, process efficiency, and traceability. This study employed a knowledge-based visualization technique to create a vision beyond other review studies on the blockchain-based supply chain. We used bibliometric and network analysis to synthesize the previous literature. In total, 431 articles in the timespan of 2017 to April 2022 from Scopus and Web of Science (WOS) databases were analyzed after applying search string, inclusion, and exclusion criteria. Basic information was extracted from initial data screening; then, data was analyzed on the grounds of co-occurrence, bibliographic coupling, citation, co-authorship, and co-citation analysis. In addition, thematic analysis was performed to analyze the content of the previous studies, adopted research methods, and dynamic industries in the literature. Besides all these, we identified various research gaps and proposed research directions for future study. We believe that this study provides adequate knowledge to academic scholars and supply chain practitioners to fast-track the current research in the supply chain domain using blockchain technology.",30,6,14029,14049,Traceability; Scopus; Supply chain; Blockchain; Computer science; Data science; Citation analysis; Thematic analysis; Supply chain management; Bibliometrics; Citation; Knowledge management; Data mining; World Wide Web; Business; Qualitative research; Sociology; MEDLINE; Political science; Marketing; Software engineering; Social science; Computer security; Law,Bibliometric analysis; Blockchain; Dynamic industries; Research methodology; Supply chain; Theme analysis,Blockchain; Technology; Industry; Information Dissemination,,Central Universities Fundamental Research Foundation for Chang'an University (300102231603),https://link.springer.com/content/pdf/10.1007/s11356-022-24844-2.pdf https://doi.org/10.1007/s11356-022-24844-2,http://dx.doi.org/10.1007/s11356-022-24844-2,36571684,10.1007/s11356-022-24844-2,,PMC9791637,0,000-027-768-030-400; 001-223-177-378-370; 001-462-828-664-767; 001-550-853-274-787; 005-112-082-100-644; 007-020-271-129-280; 008-092-872-335-265; 009-326-902-354-455; 010-474-184-242-896; 010-802-612-402-105; 011-301-822-302-672; 012-162-081-192-515; 012-984-493-459-426; 013-507-404-965-47X; 014-080-159-878-749; 015-651-241-950-941; 016-819-194-616-838; 017-750-600-412-958; 018-716-143-955-726; 019-777-648-714-237; 020-060-477-776-915; 020-760-850-466-120; 020-946-052-830-560; 027-208-401-152-367; 027-396-885-561-116; 027-519-289-817-346; 027-660-409-834-267; 027-847-208-120-049; 028-689-228-625-920; 029-749-781-626-177; 030-696-044-917-387; 031-503-076-934-395; 034-545-974-804-95X; 034-609-925-501-274; 034-967-242-757-748; 036-121-841-799-732; 038-631-624-874-022; 039-081-055-657-126; 040-577-892-840-74X; 042-394-228-997-686; 049-162-815-899-249; 049-391-379-302-694; 050-027-809-740-200; 050-893-374-534-416; 051-266-797-600-087; 051-472-143-393-282; 052-622-518-933-044; 055-412-405-302-987; 055-526-856-766-92X; 056-406-541-298-666; 056-981-166-310-491; 058-692-073-081-206; 059-145-397-572-574; 061-567-825-976-594; 062-912-057-319-217; 063-645-621-520-775; 064-534-120-800-562; 070-734-210-302-27X; 071-176-890-544-418; 071-195-175-766-314; 073-531-395-452-205; 073-775-823-470-313; 075-374-692-300-714; 077-288-253-889-899; 077-657-517-956-786; 078-542-170-294-248; 079-532-899-441-414; 079-627-085-622-365; 083-860-858-902-680; 085-583-514-139-319; 086-304-179-594-163; 086-583-029-287-517; 088-520-232-433-406; 090-754-045-510-625; 093-393-149-291-04X; 095-895-006-249-04X; 097-248-646-916-092; 097-759-335-124-834; 101-801-681-188-709; 105-032-479-005-413; 111-684-124-613-63X; 112-938-897-652-028; 113-776-567-679-25X; 117-250-633-292-539; 119-478-952-772-197; 121-550-819-768-936; 124-301-674-681-486; 130-051-983-839-839; 130-705-982-455-630; 132-619-830-943-223; 137-187-683-568-552; 141-407-090-706-370; 141-823-472-367-346; 149-198-291-671-12X; 149-322-612-082-39X; 151-064-433-317-256; 153-993-151-696-648; 158-020-983-863-972; 163-414-529-801-707; 168-382-271-557-986; 171-115-818-447-150; 187-703-070-908-528; 192-146-505-739-615,28,true,,bronze -159-593-473-299-384,Sustainability and its role in human well-being: A bibliometric analysis,2022-05-27,2022,journal article,Public Health and Toxicology,27328929,E.U. European Publishing,,Flora Zaragkali; Maria Gialeli; Andreas Troumbis; Georgios Antasouras; Constantinos Giaginis; Georgios Vasios,"1. Aria M, Cuccurullo C. bibliometrix : An R-tool for comprehensive science mapping analysis. J Informetr. 2017;11(4):959-975. doi:10.1016/j.joi.2017.08.007 CrossRef Google Scholar",2,Supplement 1,,,Sustainability; Ecology; Biology,,,,,http://www.publichealthtoxicology.com/dl/faf76f7353523be0426c363300cce56b/ https://doi.org/10.18332/pht/149672,http://dx.doi.org/10.18332/pht/149672,,10.18332/pht/149672,,,0,002-052-422-936-00X; 013-507-404-965-47X; 015-485-770-426-896; 047-134-478-431-993,0,true,cc-by-nc,gold -159-669-261-958-104,Navigation of Knowledge: the Impact of COVID-19 on Pregnancy-a Bibliometric Analysis.,2023-07-24,2023,journal article,"Reproductive sciences (Thousand Oaks, Calif.)",19337205; 19337191,Springer Science and Business Media LLC,United States,Jingrouzi Wu; Buzi Cao; Jingnan Liao; Yuan Li; Guangxiu Lu; Fei Gong; Ge Lin; Mingyi Zhao,,30,12,3548,3562,Pandemic; Bibliometrics; Pregnancy; Coronavirus disease 2019 (COVID-19); Medicine; Family medicine; Library science; Disease; Pathology; Computer science; Biology; Infectious disease (medical specialty); Genetics,Bibliometrics; COVID-19; Complications; Pregnancy; Women,"Infant, Newborn; Pregnancy; Humans; Female; COVID-19; SARS-CoV-2; Pandemics; Bibliometrics; Pregnancy Complications",,,,http://dx.doi.org/10.1007/s43032-023-01312-x,37488404,10.1007/s43032-023-01312-x,,,0,000-053-817-430-304; 007-581-010-608-814; 012-648-174-183-677; 014-046-054-731-186; 017-106-513-763-381; 017-838-929-630-105; 020-974-942-606-809; 023-284-178-395-495; 025-027-466-562-492; 028-576-989-907-761; 033-237-583-931-803; 033-753-706-802-763; 038-836-105-877-765; 043-383-185-040-958; 044-482-845-072-69X; 045-078-742-928-450; 045-157-967-620-452; 045-749-163-826-489; 052-616-430-376-57X; 054-653-014-292-831; 055-256-307-820-359; 055-915-599-652-954; 058-682-272-907-577; 075-587-868-242-888; 078-183-242-276-646; 078-981-566-418-31X; 081-222-547-388-419; 088-303-766-735-301; 089-643-483-718-330; 090-563-465-555-30X; 090-610-792-947-190; 093-947-913-531-806; 094-083-953-353-160; 098-065-278-335-167; 098-841-791-712-559; 100-573-760-837-713; 102-541-557-697-336; 108-121-686-083-24X; 112-414-536-255-839; 116-866-277-633-745; 120-469-659-828-308; 131-770-374-031-022; 145-404-751-642-004; 148-654-880-231-843; 149-532-116-623-447; 153-580-772-717-047; 159-835-667-725-723; 168-247-437-588-466; 172-449-770-512-529; 175-396-168-857-818,0,false,, -159-879-223-697-404,Bibliometrix: An Easy Yet Powerful Approach for Quantitative and Qualitative Analyses of Scholarly Literature,2024-05-13,2024,journal article,Information Research Communications,30410800,Manuscript Technomedia LLP,,Mueen Ahmed KK,,1,1,43,45,Data science; Computer science; Management science; Epistemology; Engineering; Philosophy,,,,,,http://dx.doi.org/10.5530/irc.1.1.7,,10.5530/irc.1.1.7,,,0,,0,false,, -160-045-452-286-865,Recent advances in freshwater zooplankton in a conservation hotspot: Türkiye case,2025-02-26,2025,journal article,Hydrobiologia,00188158; 15735117,Springer Science and Business Media LLC,Netherlands,Gürçay Kıvanç Akyıldız; Ahmet Altındağ; Ülkü Nihan Tavşanoğlu,"Abstract; Freshwater ecosystems are vital for providing essential services such as water supply and food production. However, increasing human demands have led to significant environmental degradation in these ecosystems. Türkiye, recognized as a global biodiversity hotspot, faces numerous threats from altered flow regimes, land-use changes, pollution, and invasive species. Despite these challenges, Türkiye’s diverse environments support a rich assemblage of zooplankton, with over 662 identified taxa spanning rotifers, cladocerans, and copepods. This study conducted a bibliometric analysis of zooplankton research at both global and national (Türkiye) levels to understand research trends, identify knowledge gaps, and highlight key areas of focus. Globally, stress factors and climate change dominate the research agenda, whereas, in Türkiye, topics such as abundance, diversity, water quality, and bioindicators have gained attention, albeit with relatively low frequency. Since 2013, these themes have shaped the direction of Turkish zooplankton research. The findings of this study emphasize the need for targeted research to better understand the impacts of environmental stressors on zooplankton communities in Türkiye, while also contributing to the global discourse on ecosystem functionality. By using zooplankton as key biotic indicators, this research offers insights into ecosystem health, providing critical information for future conservation and management efforts.",852,10,2581,2594,Zooplankton; Ecology; Hotspot (geology); Geography; Fishery; Biology; Geology; Geophysics,,,,Cankırı Karatekin University,,http://dx.doi.org/10.1007/s10750-025-05822-4,,10.1007/s10750-025-05822-4,,,0,000-235-426-098-014; 003-119-052-276-760; 003-928-110-320-038; 003-937-192-666-730; 008-470-924-241-339; 010-181-450-996-756; 011-550-731-454-053; 011-956-516-835-97X; 013-105-696-261-21X; 013-507-404-965-47X; 019-021-504-306-779; 025-433-824-373-67X; 029-370-907-449-385; 030-984-307-599-859; 031-328-716-653-554; 033-845-533-878-687; 036-643-189-666-426; 038-595-076-554-89X; 041-674-973-974-636; 044-491-803-242-472; 047-825-065-710-364; 048-302-993-857-346; 051-825-399-645-675; 061-331-050-906-492; 061-673-071-433-137; 064-712-637-246-292; 064-942-610-626-061; 065-677-093-599-65X; 070-313-757-209-591; 070-693-235-643-689; 073-113-519-896-982; 075-347-083-124-336; 075-749-738-891-387; 076-091-802-118-857; 078-239-671-532-425; 091-073-530-034-151; 092-097-187-307-29X; 093-048-509-187-872; 094-137-573-563-327; 094-559-331-677-559; 095-472-394-306-995; 096-483-612-826-623; 100-191-091-196-838; 100-847-461-895-812; 101-430-877-637-078; 103-332-733-802-605; 109-131-862-621-912; 109-925-613-541-457; 116-478-768-633-809; 130-424-017-379-129; 141-815-463-294-317; 152-322-641-204-294; 171-159-987-378-63X; 192-817-852-899-394,2,true,cc-by,hybrid -160-270-945-551-007,Research Mapping of Trauma Experiences in Autism Spectrum Disorders: A Bibliometric Analysis. Bibliometrix file,2023-02-21,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Osvaldo Hernández-González; Andrés Fresno-Rodríguez; Rosario Spencer-Contreras; Raúl Tárraga-Mínguez; Daniela González-Fernández; Francisca Sepúlveda-Opazo,This is the Bibliometrix file of the paper entitled: Research Mapping of Trauma Experiences in Autism Spectrum Disorders: A Bibliometric Analysis.,,,,,Autism; Computer science; Psychology; Developmental psychology,,,,,https://zenodo.org/record/7660173,http://dx.doi.org/10.5281/zenodo.7660173,,10.5281/zenodo.7660173,,,0,,0,true,cc-by,gold -160-438-054-356-116,Economists in Ukraine: who are they and where do they publish?,,2018,,,,,,Maksym Obrizan,"This paper analyses 1,672 articles published in English by economists working in Ukraine over 1991-2017 using SCOPUS database and bibliometrix package in R. Between 2011 and 2012 when the number of published papers increased more than ten times with Actual Problems of Economics and Economic Annals-XXI being the two most important outlets accounting for more than 70 percent of all publications. Despite this increased visibility the citation counts show rather modest contribution of economists in Ukraine. Regression analysis of citations indicates that articles with a foreign co-author and Digital Object Identifier are more likely to receive citations.",1,1,2,9,Regression analysis; Library science; Political science; Bibliometrics; Ranking; Citation; Visibility (geometry); Digital Object Identifier; Publication; Scopus,,,,,https://ideas.repec.org/a/kse/chasop/v1y2018i1p2-9.html,https://ideas.repec.org/a/kse/chasop/v1y2018i1p2-9.html,,,3142431364,,0,,0,false,, -160-944-646-222-690,Research progress and hotspot analysis of type B aortic dissection: a bibliometric analysis from 2004 to 2023.,2025-03-20,2025,journal article,Journal of cardiothoracic surgery,17498090,Springer Science and Business Media LLC,United Kingdom,Zhen-Yi Zhao; Shu-Li Zhou; Yun Peng; Can Cui; Liang-Geng Gong,"This study aimed to analyze and visualize the research on type B aortic dissection (TBAD) over the past 20 years through bibliometric research. To reveal the development process of TBAD research and the transitions of research hotspots. Literatures was retrieved from the Web of Science Core Collection. The analysis utilized tools such as Microsoft Office Excel, VOSviewer and CiteSpace for bibliometric mapping and visualization, including assessing publication volumes and constructing collaborative networks and keyword burst graphs. A total of 1391 related articles or reviews on TBAD were included. The number of annual publications is steadily increasing. China was the top country in terms of the number of publications. University of Michigan (n = 60) was the most productive university. The Journal of Vascular Surgery (n = 183) was the most published and co-cited journal. Keywords burst analysis showed that ""guidelines"", ""spinal-cord ischemia"", ""society"", ""impact"", and ""aortic remodeling"" were the most frequently used keywords in recent years. In general, the research focus of TBAD has gradually changed from selecting the surgical method to the best clinical management and patient prognosis after thoracic endovascular aortic repair (TEVAR). Promoting positive aortic remodeling and aortic hemodynamics may be the research hotspots in the future.",20,1,157,,Aortic dissection; Cardiothoracic surgery; Cardiac surgery; Medicine; Cardiology; Internal medicine; Surgery; Aorta,Bibliometric; Hemodynamics; Spinal cord ischemia (SCI); Stent-graft placement; Thoracic endovascular aortic repair (TEVAR); Type B aortic dissection (TBAD),"Humans; Bibliometrics; Aortic Dissection/surgery; Biomedical Research/trends; Aortic Aneurysm, Thoracic/surgery",,National Natural Science Foundation of China (82260342),,http://dx.doi.org/10.1186/s13019-025-03400-2,40114257,10.1186/s13019-025-03400-2,,PMC11924762,0,002-052-422-936-00X; 002-417-145-680-024; 002-898-204-316-012; 003-860-483-029-405; 007-072-850-521-126; 012-108-755-874-487; 013-507-404-965-47X; 015-576-171-124-259; 017-196-332-612-957; 018-834-137-959-752; 021-412-888-264-618; 024-482-400-592-179; 025-277-947-572-458; 029-411-517-174-265; 031-178-865-295-374; 031-194-150-546-133; 036-611-518-174-988; 037-129-607-997-143; 047-331-077-444-171; 063-053-515-428-925; 063-857-675-328-038; 070-290-819-334-357; 070-695-198-492-496; 073-225-305-672-584; 074-249-016-940-522; 077-919-873-072-845; 082-097-274-637-323,0,true,"CC BY, CC0",gold -161-111-813-714-626,Bibliometric Review on the Business Management Field,2023-02-03,2023,journal article,Scientific Annals of Economics and Business,25013165; 25011960,Editura Universitatii Alexandru Ioan Cuza din Iasi,Romania,Tayfun Arar; Gülşen Yurdakul,"The purpose of this article is to review the business management field evolution from 2000 up to date and to map the conceptual, social, and intellectual structure of the research in this field. Data were collected from the WoS database, comprising 12,145 articles published between 2000 and 2022. Several bibliometric techniques were applied, including analysis of co-words, co-citation, bibliographic coupling, and co-authorship networks in addition to performance analysis. VosViewer and the Bibliometrix/Biblioshiny packages were used to perform the analyses. Besides revealing the evolution of the business management field, the results identify the most active and influential authors, articles, journals, and topics in this field.",70,2,301,334,Bibliographic coupling; Field (mathematics); Bibliometrics; Citation analysis; Citation; Data science; Knowledge management; Co-citation; Sociology; Computer science; Management science; Library science; Engineering; Mathematics; Pure mathematics,,,,,http://saeb.feaa.uaic.ro/index.php/saeb/article/download/1810/290 https://doi.org/10.47743/saeb-2023-0002,http://dx.doi.org/10.47743/saeb-2023-0002,,10.47743/saeb-2023-0002,,,0,000-836-922-227-149; 001-123-810-924-376; 002-943-615-906-965; 003-288-024-797-427; 004-130-251-802-288; 005-463-376-595-907; 005-729-137-620-912; 006-132-633-628-096; 010-255-085-056-887; 013-507-404-965-47X; 013-524-854-219-241; 018-064-589-271-782; 018-742-175-434-449; 019-764-117-584-856; 022-774-738-500-720; 023-033-258-332-236; 025-122-155-978-605; 026-169-050-342-031; 026-499-871-558-122; 026-845-733-807-089; 027-818-251-458-51X; 029-420-167-353-195; 030-324-599-553-057; 030-755-802-133-133; 033-171-354-077-456; 034-263-152-088-952; 036-209-087-418-569; 037-158-060-204-666; 041-722-699-739-10X; 042-028-762-478-755; 045-993-333-977-461; 046-013-374-617-606; 046-992-864-415-70X; 049-391-379-302-694; 050-620-415-061-78X; 051-647-739-244-271; 052-295-133-428-13X; 054-455-624-110-575; 055-273-552-334-543; 057-654-040-328-176; 060-154-619-670-904; 077-930-616-453-628; 078-810-782-159-483; 083-323-919-304-737; 089-888-753-187-062; 095-010-304-880-824; 095-039-979-917-137; 096-287-329-816-51X; 099-963-692-233-538; 101-752-490-869-458; 104-043-879-413-130; 106-619-997-653-532; 111-819-171-804-346; 112-036-430-871-021; 112-533-001-418-656; 114-672-162-453-463; 115-373-591-444-545; 115-482-499-323-938; 120-363-222-035-852; 120-974-286-046-262; 123-628-833-025-039; 125-212-750-683-224; 130-057-480-639-007; 130-602-202-936-694; 133-293-776-235-662; 141-200-607-894-303; 154-710-114-426-124; 155-651-272-672-303; 161-058-916-768-547; 169-534-328-124-900; 172-959-949-589-454; 179-608-372-698-452; 194-739-135-241-524; 195-638-802-395-994,6,true,cc-by-nc-nd,gold -161-157-664-520-345,The Future Direction of Halal Food Additive and Ingredient Research in Economics and Business: A Bibliometric Analysis,2023-03-24,2023,journal article,Sustainability,20711050,MDPI AG,Switzerland,La Ode Nazaruddin; Balázs Gyenge; Maria Fekete-Farkas; Zoltán Lakner,"The increasing growth trend of the global Muslim population implies an increase in the consumption of halal products. The importance of the halal market attracts much attention from many stakeholders, including academia/researchers. Many scholars have conducted studies on halal topics. However, these studies cover broad topics, such as ICT potential in the halal sector, the halal supply chain, Islamic Law, and other halal studies related to natural sciences. This study aims to study the research gap and future trends of halal food additive and ingredient research in business and economics using bibliometric analysis. The data were obtained from the Scopus database from 1999 to 2022. The authors analyzed the keyword “Halal Consumption and Production” by using the general keyword “Halal or Haram Additive and Ingredient”. The dataset was uploaded on VOSviewer and R language (Bibliometrix) software. This study found a deficit of studies on halal food additives and ingredients in business and economics. The co-occurrence network output demonstrated that future studies on halal food additives and ingredients should consider clusters that have lower density and central positions, such as production–consumption and the supply chain, healthy foods, and the logistics market and health effects. The Bibliometrix strategic diagram of the 2020–2022 thematic evolution demonstrates a research gap in three out of four quadrants (i.e., emerging or declining, basic, and motor themes). This study suggests potential research areas in the field of halal food additives and ingredients, such as ethical and sustainable sourcing, responsible consumption, consumer sovereignty, international trade, economic modeling, food security, green/sustainable supply chain, and halal regulation and product safety.",15,7,5680,5680,Ingredient; Consumption (sociology); Business; Supply chain; Marketing; Food industry; Food security; Production (economics); Population; Economics; Geography; Social science; Food science; Agriculture; Chemistry; Macroeconomics; Demography; Archaeology; Sociology,,,,,https://www.mdpi.com/2071-1050/15/7/5680/pdf?version=1679975581 https://doi.org/10.3390/su15075680,http://dx.doi.org/10.3390/su15075680,,10.3390/su15075680,,,0,000-254-460-594-488; 001-879-143-444-060; 002-052-422-936-00X; 002-553-450-350-343; 004-199-515-598-993; 004-536-831-964-857; 006-809-093-370-283; 009-639-107-865-448; 013-507-404-965-47X; 014-339-457-410-597; 019-529-035-789-815; 019-703-321-392-676; 019-902-910-326-150; 021-382-797-777-739; 022-401-995-027-936; 023-378-334-979-263; 027-672-720-298-151; 028-645-479-792-382; 029-287-496-527-23X; 031-416-570-394-94X; 033-068-338-939-030; 036-058-758-172-251; 036-278-554-244-588; 039-072-289-701-535; 039-454-488-728-371; 044-295-803-996-17X; 044-939-411-510-629; 045-058-711-981-285; 046-336-570-980-53X; 047-134-478-431-993; 050-664-965-270-417; 051-647-739-244-271; 053-238-599-159-31X; 053-360-941-677-139; 058-825-552-813-503; 058-860-931-027-442; 069-876-219-934-140; 078-005-300-240-181; 080-751-769-629-641; 082-024-690-305-70X; 083-966-967-982-726; 084-549-437-799-456; 097-379-723-219-304; 098-188-500-424-380; 104-126-029-218-455; 104-816-925-056-122; 108-507-747-172-599; 110-812-813-638-485; 111-032-138-733-516; 111-299-760-190-104; 119-347-168-129-712; 119-594-392-215-090; 119-844-654-287-983; 123-530-694-967-96X; 123-578-706-739-466; 125-769-113-952-864; 130-844-773-038-945; 131-695-312-530-611; 132-857-624-830-395; 134-952-999-545-556; 136-035-616-262-124; 138-532-177-783-568; 139-539-851-907-306; 142-562-462-367-91X; 156-415-541-949-588; 157-409-761-387-113; 163-581-972-407-913; 168-891-985-384-234; 169-289-430-403-088; 170-303-382-791-170; 174-382-591-218-702; 180-548-664-085-520; 183-124-256-865-552; 183-145-980-056-089; 188-596-589-055-74X,12,true,,gold -161-368-014-719-838,Mapping the youth soccer: A bibliometrix analysis using R-tool.,2023-06-20,2023,journal article,Digital health,20552076,SAGE Publications,United States,Bo Liu; Chang-Jing Zhou; Hao-Wei Ma; Bo Gong,"In recent years, there has been an increase in the scientific production of youth soccer. However, a panoramic map of research on this subject does not exist. The aim of this study was to identify global research trends in youth soccer over time, among the main levels of analysis: sources, authors, documents, and keywords. The bibliometric software Biblioshiny was used to analyze 2606 articles in Web of Science (WoS) published between 2012 and 2021. The main conclusion is that US and UK scholars dominate the research; the topics of research are changing with the real needs, and research on the topic of performance has been of interest to scholars; talent identification and development, performance, injury prevention, and concussion are the studies of interest to scholars in this area. This finding, which offers a global picture of youth soccer research over time, can help future research in this or similar domains.",9,,20552076231183550,,Identification (biology); Subject (documents); Web of science; Concussion; Sports science; Data science; Psychology; Computer science; Political science; Library science; Poison control; Injury prevention; MEDLINE; Medicine; Botany; Environmental health; Law; Biology,WoS; Youth soccer; bibliometrix; biliometric analysis,,,National Social Science Foundation of China,https://journals.sagepub.com/doi/pdf/10.1177/20552076231183550 https://doi.org/10.1177/20552076231183550,http://dx.doi.org/10.1177/20552076231183550,37361439,10.1177/20552076231183550,,PMC10286214,0,001-529-234-291-493; 002-596-427-175-559; 002-715-745-296-371; 002-901-942-861-930; 007-080-524-001-782; 008-397-934-363-219; 008-769-110-307-294; 009-010-232-742-887; 010-065-762-504-134; 011-098-553-617-631; 011-275-600-647-265; 011-301-822-302-672; 011-920-013-098-686; 013-507-404-965-47X; 013-524-854-219-241; 014-262-069-040-886; 015-290-382-056-74X; 015-428-366-171-181; 016-128-620-448-177; 016-304-233-897-925; 017-798-419-670-509; 018-419-611-150-662; 018-602-101-705-125; 020-773-740-157-936; 027-133-252-847-320; 029-126-293-342-887; 030-702-967-637-699; 030-835-584-766-388; 037-087-266-450-875; 037-434-522-559-719; 038-771-235-537-959; 039-173-191-310-643; 041-113-519-700-862; 045-702-723-168-624; 046-749-890-503-64X; 048-929-312-213-991; 049-255-059-772-172; 051-647-739-244-271; 052-293-595-769-458; 054-818-565-070-154; 058-094-672-066-905; 058-849-312-988-538; 060-110-039-971-60X; 063-000-571-370-589; 063-326-560-074-32X; 064-162-329-834-216; 064-400-499-357-900; 069-793-880-691-299; 073-730-402-611-078; 075-277-872-809-054; 083-308-326-806-496; 089-553-288-200-131; 092-011-142-472-603; 093-084-263-732-954; 096-172-587-138-774; 101-519-311-238-60X; 103-890-813-098-052; 121-772-861-647-816; 130-508-610-986-534; 132-279-191-171-571; 138-141-167-254-891; 145-979-961-398-502; 153-648-726-256-049; 159-492-288-881-695; 166-019-140-891-707; 172-983-162-268-067; 173-848-637-692-14X,13,true,"CC BY, CC BY-NC, CC BY-NC-ND",gold -161-455-925-653-193,AI: Challenges for contemporary digital education,2025-06-19,2025,journal article,EthAIca,30727952,AG Editor (Argentina),,Carlos Alberto Gómez Cano,"Introduction: This study analyzes the challenges of artificial intelligence (AI) in digital education between 2019 and 2022, using a bibliometric approach. The research arose from the need to systematize existing knowledge and guide future lines of work in this emerging field.  Methodology: A search was conducted in Scopus, Web of Science, Google Scholar, and ERIC, using terms such as ""AI,"" ""digital education,"" and ""challenges."" The data was filtered by year, language, and document type, and processed with tools such as VOSviewer and Bibliometrix to analyze productivity, collaborations, and thematic trends. Results: Key authors and institutions, collaborative networks, and recurring themes, such as ethics, adaptive learning, and teacher training, were identified. Scientific production showed steady growth, with a predominance of publications in English. Conclusions: The study highlights the main challenges of AI in digital education and highlights the need to investigate its ethical and pedagogical impact. The methodology employed provides a basis for future reviews.",4,,155,,,,,,,,http://dx.doi.org/10.56294/ai2025155,,10.56294/ai2025155,,,0,002-942-889-536-83X; 003-954-720-966-142; 006-819-576-085-62X; 009-604-318-704-919; 009-606-708-042-518; 011-141-734-131-279; 011-815-921-101-161; 012-932-063-910-649; 017-736-478-693-192; 018-616-849-696-094; 023-061-472-475-80X; 024-266-874-654-072; 028-649-814-583-309; 029-693-567-251-749; 032-973-270-577-240; 034-447-007-410-358; 041-121-368-633-649; 043-012-706-754-495; 048-219-713-120-968; 050-037-437-060-421; 052-008-161-244-210; 052-812-270-293-81X; 053-760-941-442-404; 057-467-679-084-068; 065-460-946-529-454; 066-474-273-757-922; 069-834-100-390-400; 070-293-669-058-126; 076-071-978-553-280; 078-313-359-890-706; 082-093-169-349-743; 083-785-488-339-853; 086-044-580-403-791; 090-539-593-152-468; 091-530-855-152-480; 092-342-401-651-97X; 092-538-043-559-966; 095-825-676-165-802; 104-160-629-523-452; 104-163-649-788-347; 115-501-575-336-521; 121-871-090-564-927; 124-068-932-921-158; 125-383-579-616-633; 135-156-303-743-749; 144-719-186-482-430; 168-582-450-317-992; 176-481-668-058-601; 180-805-106-928-866; 190-320-474-436-619; 196-227-331-007-261,0,false,, -161-529-052-457-212,"Bibliometric analysis of neutrophil elastase research in the post-COVID-19 era: trends, frontiers, differential mapping, and emerging trends",2025-03-26,2025,journal article,Discover Applied Sciences,30049261,Springer Science and Business Media LLC,,Siddig Ibrahim Abdelwahab; Adel S. Al-Zubairi; Manal Mohamed Elhassan Taha; Bassem Oraibi; Hassan Ahmad Alfaifi; Ieman A. Aljahdali; Ahmed Ali Jerah; Saleh M. Abdullah; Abdullah Farasani; Yasir Babiker; Aied M. Alabsi; Abdalla Elmanna,"Background/objectives Neutrophil elastase (NE) is a serine protease primarily produced by neutrophils, playing a pivotal role in various physiological and pathological processes. This study aimed to provide insights into the research landscape surrounding NE and its implications in the post-COVID-19 era. Methods The current study employed a cross-sectional design based on bibliometric analysis. Articles were retrieved from the Scopus database and analyzed quantitatively using VOSviewer and Bibliometrix software to evaluate publication trends, authorship patterns, citation dynamics, and emerging research themes. Results The analysis highlighted countries and institutions significantly contributing to NE research, revealing global trends and hotspots. Collaboration patterns were assessed, showcasing productive partnerships within the field. Key research topics identified include NE’s roles in inflammation, tissue damage, and disease pathogenesis. The COVID-19 pandemic reshaped the thematic map of NE research, driving focus toward NE's involvement in COVID-19 pathophysiology, therapeutic interventions, and its role in complications associated with the disease. Conclusions This bibliometric analysis offers a comprehensive view of NE research, focusing on its functions, pathophysiological roles, and implications for diseases such as lung disorders and COVID-19, providing a foundation for future research directions.",7,4,,,Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Coronavirus Infections; Geography; Virology; Medicine; Internal medicine; Disease; Outbreak; Infectious disease (medical specialty),,,,"Deanship of Graduate Studies and Scientific Research, Jazan University, Saudi Arabia",,http://dx.doi.org/10.1007/s42452-025-06551-y,,10.1007/s42452-025-06551-y,,,0,000-772-639-632-43X; 001-268-594-355-531; 002-052-422-936-00X; 003-458-961-930-674; 005-840-536-451-736; 006-574-406-694-374; 006-914-393-177-674; 010-182-201-971-018; 011-108-346-467-649; 012-133-517-377-578; 012-911-943-150-577; 013-406-968-677-438; 013-507-404-965-47X; 019-165-899-846-851; 020-895-902-449-348; 023-558-107-537-084; 024-278-876-400-71X; 028-789-518-142-79X; 030-294-920-579-823; 035-728-253-053-357; 042-745-977-336-326; 044-436-259-847-344; 045-185-479-702-502; 052-591-627-108-810; 055-481-293-874-612; 055-760-878-098-892; 057-432-136-863-081; 057-642-305-386-470; 059-686-514-842-396; 068-371-633-724-376; 076-498-170-063-038; 079-686-428-506-658; 086-223-702-023-994; 086-474-683-763-95X; 087-290-853-763-988; 094-454-509-311-343; 096-513-492-458-380; 101-948-116-107-204; 101-966-558-240-159; 104-110-389-428-601; 106-023-581-618-541; 111-745-127-502-173; 114-785-518-344-913; 117-102-212-989-19X; 136-552-713-701-278; 144-743-516-342-191; 146-424-664-044-270; 148-167-679-984-837; 159-659-998-921-489; 167-048-035-620-613; 172-149-619-340-766; 176-240-142-514-724; 188-989-715-052-708,0,true,"CC BY, CC BY-NC-ND",gold -161-868-758-683-656,Trends and Perspectives on Tax Benefits Research,2024-10-18,2024,book chapter,Advances in public policy and administration (APPA) book series,24756644; 24756652,,,Carlos Lucas; Sérgio Nuno da Silva Ravara Almeida Cruz; Cecília Carmo,"Reducing taxation is a relevant and cross-cutting issue in society, at the level of governments, companies and citizens. There are currently a large number of scientific publications on this subject. The aim of this study is to present a mapping of scientific production on the subject of tax benefits, which will make it possible to understand the evolution and trends of research in this area. A bibliometric analysis was carried out using the Bibliometrix tool, based on the documents available on the Scopus and Web of Science platforms. The results show that the greatest growth in research on this topic has occurred from the beginning of this century to the present day. The use of dominant expressions is also observed, resulting in two clusters that separate research into tax benefits at a company level from those at an individual level. This result suggests the need for future studies to deal separately with corporate and personal tax benefits.",,,471,512,Economics; Political science; Business,,,,,,,,,,,0,,0,false,, -161-901-902-504-053,Humanitarian supply chain: a bibliometric analysis and future research directions,2020-04-06,2020,journal article,Annals of Operations Research,02545330; 15729338,Springer Netherlands,Netherlands,Samuel Fosso Wamba,"Humanitarian supply chain (HSC) has attracted enormous interest from both practitioners and academics lately, mainly because of its essential role in curbing the increase in human-made and natural disasters. Knowing what has been done in the field so far as to design a robust research agenda to tackle future HSC challenges is an important research objective. In this study, a bibliometric analysis was conducted to assess the current level of research on the HSC. A search of documents dealing with HSC was realized in the Web of Science database, a world-leading publisher-independent global citation database. The search identified 1152 documents, and the data collected was analyzed by means of a bibliometric tool called Bibliometrix. Key findings are presented and discussed, followed by some potential future research avenues.",,,1,27,Supply chain; Natural disaster; Political science; Data science; Citation database; Bibliometric analysis; Important research; Field (computer science),,,,,https://link.springer.com/article/10.1007/s10479-020-03594-9,https://link.springer.com/article/10.1007/s10479-020-03594-9,,,3015468990,,0,001-158-030-451-387; 003-173-724-587-834; 004-357-427-046-217; 004-422-382-484-093; 005-655-282-466-545; 010-612-118-670-49X; 010-678-247-632-774; 011-848-196-551-792; 013-507-404-965-47X; 013-636-396-823-084; 026-557-135-847-551; 029-241-888-396-124; 033-072-313-748-096; 033-978-638-041-380; 035-443-977-306-787; 038-435-051-609-96X; 038-828-788-406-611; 039-180-555-316-153; 039-766-777-162-370; 041-818-814-241-005; 043-164-786-791-108; 043-237-625-216-246; 045-993-333-977-461; 048-233-063-914-715; 049-702-114-721-178; 051-638-982-159-179; 053-386-179-291-386; 055-666-469-824-784; 058-264-021-351-517; 058-575-445-685-033; 059-363-584-917-115; 059-502-333-665-846; 061-427-729-152-793; 061-678-439-796-853; 062-056-684-388-052; 062-522-687-734-50X; 063-050-462-225-169; 063-923-482-584-492; 064-933-858-519-329; 065-241-933-308-636; 066-771-116-851-65X; 069-079-608-898-217; 069-758-661-058-369; 074-279-238-515-510; 076-986-699-509-469; 079-821-815-152-748; 081-434-022-967-666; 088-384-837-898-640; 095-423-844-475-630; 097-322-543-563-717; 100-958-552-873-362; 104-495-326-573-684; 112-406-959-820-385; 112-679-068-880-337; 115-321-225-877-872; 118-834-446-029-757; 124-301-674-681-486; 132-550-313-257-580; 146-301-107-506-372; 147-400-828-228-309; 149-459-172-615-347; 149-879-244-312-11X; 152-641-033-222-382; 156-399-453-526-705; 175-543-825-459-682,25,false,, -161-948-530-011-853,Gynecological Cancer Research in India: A Bibliometric Analysis,2024-08-22,2024,journal article,Indian Journal of Surgery,09722068; 09739793,Springer Science and Business Media LLC,India,Varsha Gahane; Yogesh Deshpande,,87,2,253,266,Medicine; Bibliometrics; Cervical cancer; Cancer; Gynecology; Library science; Internal medicine; Computer science,,,,,,http://dx.doi.org/10.1007/s12262-024-04132-8,,10.1007/s12262-024-04132-8,,,0,000-188-619-071-046; 002-052-422-936-00X; 002-587-044-719-905; 002-588-681-493-907; 004-008-618-215-495; 007-063-632-033-402; 010-819-119-686-715; 013-507-404-965-47X; 013-524-854-219-241; 015-586-822-938-491; 042-167-740-200-381; 046-992-864-415-70X; 049-162-815-899-249; 051-721-270-129-366; 051-818-196-611-082; 056-079-975-939-998; 056-426-226-149-95X; 068-882-846-120-722; 087-255-710-316-116; 089-255-950-256-928; 097-388-787-090-41X; 108-069-744-786-803; 108-325-327-295-974; 109-726-720-389-508; 109-751-762-113-299; 113-776-567-679-25X; 121-813-144-996-86X; 128-217-524-056-953; 130-602-202-936-694; 134-156-718-067-387; 159-392-490-913-656; 166-790-328-343-226; 167-651-355-888-172,1,false,, -163-281-192-173-672,"Innovación Social: Definiciones, Métricas, Temáticas clave, Agentes y Enfoques de impacto",2023-10-01,2023,journal article,UCJC Business and Society Review (formerly known as Universia Business Review),26593270,Universidad Camilo Jose Cela,,Diego Rolando Minga- López; David Flores Ruiz,"This article analyses the trends in Social Innovation research published in the Social Science Citation Index (SSCI) of the Web of Science. It identifies its metrics, definitions, characteristics, agents and approaches, carrying out a bibliometric research with the software ""Bibliometrix"", as well as a bibliographic review of the 50 most cited articles. It is concluded that there is a multitude of definitions of social innovation with the common denominator being the implementation of new ideas and collaborative forms of relationship between different socio-economic agents to tackle complex social problems. Public entities are present in a significant number of articles, with concepts such as governance and co-creation emerging. However, a significant part of this research is addressed under a micro approach, which is considered necessary to increase the social impact and the transition to higher levels, meso and macro, which accommodate a greater number of agents, among which private entities stand out.",20,78,,,,,,,,,http://dx.doi.org/10.3232/ubr.2023.v20.n3.06,,10.3232/ubr.2023.v20.n3.06,,,0,,0,true,cc-by-nc,gold -163-314-769-194-792,What exists in academia on work stress in accounting professionals: a bibliometric analysis.,2022-06-24,2022,journal article,"Current psychology (New Brunswick, N.J.)",10461310; 19364733,Springer Science and Business Media LLC,United States,Margarida Rodrigues; Cidália Oliveira; Ana Borges; Mário Franco; Rui Silva,"This study aims to fill a gap in the literature by conducting the scientific and bibliometric mapping of work stress in accounting professionals, using a methodological trilogy that contributes to this topic, namely the application of the ROC curve, Prisma and R bibliometric tools. Through the analysis of a sample of 103 articles, it was found that, in order to avoid and/or overcome the levels of stress in accountants, the following factors should be taken into account: (1) a high engagement with work, (2) reduced self-efficacy perception in the decision-making process, (3) adverse consequences in the management process, and (4) high-stress levels embedded in the individual's personality. Thus, it will be necessary for the accountant to apply strategies and change the way he/she works and perceives the work, avoiding stress levels and irreversible health damage. In addition, the importance of resilience in the professional context and mindfulness may prevent high levels of stress and maybe the subject of future research.",42,26,1,22495,Psychology; Context (archaeology); Stress (linguistics); Psychological resilience; Process (computing); Work (physics); Mindfulness; Perception; Occupational stress; Applied psychology; Social psychology; Clinical psychology; Computer science; Engineering; Mechanical engineering; Paleontology; Philosophy; Linguistics; Neuroscience; Biology; Operating system,Accountant; Bibliometric; Burnout; Job stress; Mapping; SLR,,,,https://link.springer.com/content/pdf/10.1007/s12144-022-03301-w.pdf https://doi.org/10.1007/s12144-022-03301-w,http://dx.doi.org/10.1007/s12144-022-03301-w,35789626,10.1007/s12144-022-03301-w,,PMC9244524,0,000-521-547-483-717; 000-892-035-320-482; 001-055-485-280-885; 001-554-877-975-914; 002-159-916-091-051; 002-752-593-133-76X; 003-033-179-137-20X; 003-661-060-188-429; 003-974-217-453-882; 004-173-468-123-729; 006-000-701-835-763; 006-089-259-073-228; 007-160-597-859-659; 007-482-418-341-574; 008-453-634-162-718; 010-400-432-373-798; 011-048-951-665-035; 011-364-541-838-073; 011-585-347-268-811; 013-507-404-965-47X; 013-564-658-957-42X; 013-807-986-306-873; 014-569-089-418-58X; 014-687-305-577-831; 015-785-400-504-433; 015-898-152-908-332; 017-494-104-354-453; 018-820-717-106-783; 018-847-912-008-767; 019-047-136-480-073; 020-583-991-288-714; 020-771-029-003-485; 021-036-283-000-680; 021-049-115-087-062; 021-842-406-532-289; 023-838-806-896-322; 024-635-007-058-45X; 025-297-548-584-206; 025-302-119-966-613; 026-169-050-342-031; 026-469-687-630-916; 027-406-540-345-844; 030-945-805-038-518; 035-330-847-069-591; 037-098-209-265-191; 037-628-500-529-004; 038-201-865-514-749; 038-329-040-021-248; 038-623-693-995-397; 040-099-347-093-669; 041-764-521-976-410; 042-228-490-689-212; 044-062-193-899-139; 044-343-282-862-881; 045-368-114-501-494; 047-940-348-394-182; 049-427-191-307-997; 051-208-474-635-677; 051-471-414-034-608; 053-308-559-138-152; 055-205-519-075-768; 056-808-732-858-402; 059-659-914-458-058; 060-746-570-804-818; 060-963-793-515-950; 067-896-615-453-643; 068-715-824-881-688; 068-885-856-782-483; 071-205-350-775-880; 071-364-834-667-462; 073-294-521-459-269; 075-227-805-962-707; 075-301-866-096-796; 075-495-566-563-397; 077-542-066-095-090; 080-692-006-407-98X; 083-311-225-108-952; 083-456-775-799-847; 085-213-778-199-317; 085-300-287-100-525; 085-897-245-461-968; 088-666-914-143-125; 089-474-094-754-069; 089-912-307-285-647; 097-530-483-229-501; 098-493-275-046-985; 098-992-160-981-523; 099-993-498-730-415; 101-119-277-246-100; 103-431-787-851-190; 104-979-390-811-975; 111-464-973-520-37X; 112-050-733-675-387; 114-606-644-320-609; 116-706-133-864-269; 117-181-374-256-421; 120-383-308-558-089; 121-349-644-623-828; 121-454-768-157-691; 121-751-255-762-600; 123-129-712-949-386; 123-457-102-588-651; 124-512-620-875-015; 124-768-898-842-479; 127-897-380-768-083; 129-503-631-171-598; 129-609-163-656-556; 132-043-171-405-173; 134-462-035-418-817; 138-952-714-262-081; 148-099-463-779-170; 150-146-829-414-450; 152-420-184-690-109; 159-656-074-265-932; 163-107-553-758-761; 164-733-974-341-205; 169-091-179-632-580; 178-125-264-503-23X,5,true,,bronze -163-554-615-376-625,Mapping the research trends in International Journal of Tourism Policy: a bibliometric analysis and visualisation,,2022,journal article,International Journal of Tourism Policy,17504090; 17504104,Inderscience Publishers,United Kingdom,Asma Bashir; Ranjit Singh; Amitabh Mishra,"IJTP is an important journal that encourages critical examination of the emerging discourses in tourism policy. This quantitative study analyses the research papers published between 2007 and 2020 using a bibliometric approach to commemorate the 15th anniversary of IJTP. The statistical tool - bibliometrix was used to identify the leading trends and themes in the journal. This study operationalises extensive bibliometric performance and relational indicators. The results revealed that authors from different regions of the world published their work in IJTP. Tourism, tourism policy, sustainable tourism, and tourism planning were the most common keywords used. The quantitative approach has been primarily adopted in the papers of IJTP. Around 69% of the researches were completed through collaboration. The analysis conducted in the current study is in line with the other bibliometric studies considering individual journals. Therefore, this study may be relevant for researchers in tourism and hospitality scholarship.",12,3,273,273,Tourism; Scholarship; Bibliometrics; Regional science; Hospitality; Library science; Political science; Sociology; Social science; Computer science; Law,,,,,,http://dx.doi.org/10.1504/ijtp.2022.126627,,10.1504/ijtp.2022.126627,,,0,,1,false,, -163-554-811-116-273,BİLİM HARİTALAMA TEKNİKLERİ AÇISINDAN MERKEZ BANKACILIĞI YAYINLARI,2021-11-23,2021,journal article,Finansal Araştırmalar ve Çalışmalar Dergisi,13091123; 25290029,Marmara University,,Başak TANINMIŞ YÜCEMEMİŞ; Esengül ÖZDEMİR ALTINIŞIK,"Çalışmada “Merkez Bankacılığı” kavramı 1982 – 2019 yılları arasında Web Of Science Core Collection Veri Tabanından derlenerek, R Programı Bibliometrix ve VOSviewer paket programı ile bibliyometrik analize tabi tutulmuştur. Tematik evrim haritaları, atıf analizleri, endeks analizleri ve kelime analizi ile elde edilen 1581 adet makale bibliyometrik analizle incelenmiştir. Bulgu sonuçları ile sonraki dönemlerde çalışma yapacak akademisyenlere, öğrencilere, politika yapıcılara ve kurumlara alanla ilgili derinleşme, içerik analizi, kelime analizi, güncel konular ve yazarlar hakkında detaylı bilgi sunulmaktadır.",,,,,Physics; Humanities; Philosophy,,,,,https://dergipark.org.tr/tr/download/article-file/2182032 https://dergipark.org.tr/tr/pub/marufacd/issue/67868/1055285,http://dx.doi.org/10.14784/marufacd.967970,,10.14784/marufacd.967970,,,0,000-022-573-505-696; 001-845-589-432-974; 002-052-422-936-00X; 008-214-076-742-786; 010-495-710-613-419; 010-806-199-849-322; 011-301-822-302-672; 013-507-404-965-47X; 013-524-854-219-241; 015-359-016-648-668; 018-353-081-461-420; 025-970-470-471-451; 034-300-352-793-103; 035-501-116-293-163; 038-524-591-176-928; 039-222-181-198-262; 040-993-307-018-29X; 041-042-423-080-472; 044-391-122-189-743; 047-134-478-431-993; 050-491-332-745-985; 052-250-282-994-822; 066-322-005-220-595; 083-797-775-065-136; 084-026-774-797-731; 085-581-114-337-106; 091-213-054-352-088; 091-462-108-649-440; 100-294-651-994-320; 112-904-816-462-471; 121-652-742-486-910; 136-829-927-859-029; 177-882-177-384-49X,0,true,,gold -163-638-573-437-757,Mapping the knowledge landscape of the myocardial perfusion imaging with SPECT: a multidimensional bibliometric analysis,2025-02-24,2025,journal article,Clinical and Translational Imaging,22817565; 22815872,Springer Science and Business Media LLC,Italy,Laiping Xie; Jianding Peng; Xingyuan Kou; Libin Wang; Dan Deng; Huakang Li; Qing Wang; Le Li; Dingde Huang; Xiaofei Hu,,13,2,151,166,Medicine; Myocardial perfusion imaging; Interventional radiology; Radiology; Medical physics; Nuclear medicine; Perfusion; Perfusion scanning,,,,Doctoral Research Initiation Fund of Affiliated Hospital of Southwest Medical University; Senior Medical Talents Program of Chongqing for Young and Middle-aged; National Natural Science Foundation of Chongqing; Beijing Postdoctoral Research Funding Project; China Postdoctoral Science Foundation,,http://dx.doi.org/10.1007/s40336-025-00684-1,,10.1007/s40336-025-00684-1,,,0,001-707-277-467-435; 002-448-066-202-413; 005-804-369-690-845; 008-429-443-474-401; 009-087-127-770-371; 009-397-969-092-742; 010-573-502-031-917; 011-441-299-411-894; 016-689-984-533-911; 025-769-895-785-427; 026-437-792-326-610; 026-466-816-212-136; 026-531-380-820-429; 027-762-883-671-693; 031-489-009-325-655; 032-921-012-100-293; 033-291-869-067-51X; 033-934-663-888-810; 035-818-922-504-880; 038-405-048-266-970; 040-177-035-796-753; 044-870-176-628-498; 049-093-088-230-533; 049-694-756-295-273; 054-702-798-152-826; 057-879-552-640-910; 061-603-957-131-53X; 066-799-857-284-423; 073-651-556-653-849; 077-834-144-516-634; 079-884-705-524-625; 085-231-328-171-340; 088-306-010-663-487; 089-405-401-959-920; 090-122-478-546-695; 093-588-608-456-609; 097-997-814-760-110; 114-048-094-021-538; 114-601-746-887-718; 117-547-308-688-297; 128-443-699-817-481; 164-860-610-145-31X,0,false,, -163-652-299-044-037,Integrated framework of rural landscape research: based on the global perspective,2022-01-28,2022,journal article,Landscape Ecology,09212973; 15729761,Springer Science and Business Media LLC,United States,Hualin Xie; Zhenhong Zhu; Yafen He; Xiaoji Zeng; Yuyang Wen,"Context In recent years, rural landscapes have played an increasingly important role in the fields of tourism, cultural heritage and ecology. Rural landscape research (RLR), which is characterized by diversity and complexity, has attracted more and more attention from researchers. Objectives This study integrated the main research contents of RLR in the past 30 years by arranging the relevant research results and analyzing the research progress of RLR in order to understand the development trend of RLR, the distribution of research power, research hotspots and frontal research. Methods 3740 relevant literatures from 1931 to 2020 were filtrated from the WoS Core Collection Database. Those papers were quantitatively data mined and qualitatively summarized by using Bibliometrics software for mapping and analysis. Results (1) The number of articles related to RLR increased exponentially over time. The average citations per paper increased fastest from 2002 to 2005. According to the characteristics of the number of articles and the average citations per paper, RLR can be divided into three stages from 1990 to 2020: the first stage is from 1990 to 1999; the second stage is from 2000 to 2008; the third stage is from 2009 to 2020. The second stage of RLR has attracted the most international attention among three stages. (2) According to the results of research strength analysis, Europe has a great influence in RLR. The Common Agricultural Policy and the European Landscape Convention are the main driving forces for the change of rural landscape in Europe. (3) At present, the five hotspots of RLR are rural landscape planning and management, cultural ecosystem services, urban-rural conflict, the sustainable development of rural cultural heritage landscape and the impact of landscape structure on habitat. Conclusions Rural landscape research was originally developed based on geography and ecology but has now developed to a comprehensive research direction of multidisciplinary and multi-methods with social, economic, culture and other elements. At present, the object of RLR covers the ecological landscape, production landscape, and cultural landscape of rural landscape system; the content of RLR has shifted from static pattern of rural landscape to dynamic evolution process, urban-rural conflict, cultural ecosystem service and multifunctional landscape trade-off; the research paradigm of RLR has changed from single dimension to multi-dimensional, and combined with “3S” technology and various landscape ecological model software. The correlation and mechanism should be studied between the rural landscape multifunctionality based on the perspective of multidisciplinary research and rural landscape system in the future, and carry out dynamic monitoring and trend simulation, so as to clarify the thinking and paths of rural landscape multi-functional trade-off and guide the sustainable development of rural areas.",37,4,1161,1184,Landscape ecology; Nature Conservation; Perspective (graphical); Environmental planning; Geography; Sustainable development; Environmental resource management; Regional science; Ecology; Environmental science; Computer science; Biology; Habitat; Artificial intelligence,,,,National Natural Science Foundation of China; National Natural Science Foundation of China; National Natural Science Foundation of China,https://www.researchsquare.com/article/rs-792488/latest.pdf https://doi.org/10.21203/rs.3.rs-792488/v1,http://dx.doi.org/10.1007/s10980-022-01401-3,,10.1007/s10980-022-01401-3,,,0,000-358-669-325-269; 000-706-796-635-17X; 001-504-330-657-327; 001-554-753-147-797; 001-758-252-391-083; 001-854-450-804-336; 002-505-461-354-220; 003-873-667-371-566; 004-091-586-723-152; 004-527-327-568-56X; 005-093-767-578-324; 005-343-701-157-059; 005-682-935-136-767; 006-116-282-384-711; 006-523-607-605-403; 006-594-859-260-163; 007-189-912-580-009; 007-972-343-688-38X; 008-225-619-668-580; 009-151-753-527-460; 009-496-395-935-889; 010-699-976-423-238; 010-914-590-804-977; 011-089-957-105-611; 011-508-246-956-659; 011-744-508-877-032; 012-523-738-447-932; 013-306-823-378-316; 013-507-404-965-47X; 014-468-963-362-912; 017-646-467-242-506; 018-028-975-115-624; 019-240-231-735-622; 019-267-486-865-656; 019-414-144-000-596; 019-754-408-887-364; 020-019-480-536-336; 022-305-038-047-126; 022-374-598-560-71X; 022-467-721-565-106; 023-274-808-268-599; 024-963-418-714-485; 025-408-854-881-603; 025-495-961-225-44X; 025-982-408-297-083; 026-771-371-270-800; 027-983-477-173-866; 028-706-037-830-915; 028-725-626-810-449; 029-317-563-787-838; 029-769-589-390-203; 031-086-603-701-856; 031-767-178-379-811; 032-494-612-708-485; 034-368-503-114-78X; 035-445-730-149-07X; 035-533-140-870-529; 035-643-964-899-161; 036-804-933-899-784; 038-807-590-270-445; 038-965-171-666-334; 039-405-188-009-227; 039-420-271-817-183; 039-902-068-364-184; 040-059-409-331-41X; 041-393-772-245-129; 041-450-970-871-620; 043-335-061-510-691; 043-699-741-160-135; 045-078-091-609-578; 046-059-113-141-084; 047-632-491-357-654; 048-541-147-040-204; 048-723-664-493-559; 049-011-362-886-278; 049-346-208-924-920; 050-307-367-372-944; 051-187-738-397-36X; 051-919-739-161-106; 053-263-746-671-749; 053-367-753-052-993; 054-259-628-254-711; 054-270-674-810-421; 058-654-069-572-283; 061-160-518-276-008; 062-056-372-983-792; 063-417-395-621-273; 064-384-757-464-77X; 068-348-593-365-608; 068-418-218-159-803; 069-713-327-660-03X; 069-819-544-099-846; 070-653-738-249-505; 073-043-716-215-305; 074-940-525-563-91X; 075-336-397-615-388; 075-580-588-263-236; 077-810-366-865-833; 077-892-442-480-217; 077-892-592-223-427; 081-099-479-213-551; 084-788-421-393-425; 086-471-426-764-595; 088-581-927-426-949; 088-948-883-229-844; 090-514-638-026-844; 091-342-174-273-350; 094-135-450-486-940; 094-467-355-089-817; 094-908-643-308-640; 095-628-594-557-674; 096-253-286-951-280; 096-510-042-287-808; 096-992-181-947-700; 097-613-678-514-71X; 101-244-441-325-242; 101-527-340-062-623; 102-820-626-995-188; 103-597-586-363-983; 112-184-991-591-921; 113-182-470-021-20X; 113-190-851-931-274; 115-318-825-404-297; 116-834-191-948-731; 121-363-023-586-295; 122-282-111-433-880; 122-668-202-103-141; 124-056-175-798-720; 124-564-368-843-920; 128-442-068-277-074; 130-362-516-985-907; 134-120-558-009-369; 134-987-562-332-662; 149-218-888-396-840; 154-940-135-260-390; 157-900-294-441-757; 159-255-018-850-099; 166-826-142-461-007; 169-874-465-731-353; 170-541-806-199-626; 173-678-461-685-317,27,true,cc-by,green -164-210-687-800-867,Análisis bibliométrico sobre la producción científica del trabajo social digital con Scopus y bibliometrix,2020-12-07,2020,journal article,Revista Iberoamericana de la Educación,2737632x,Grupo Compas,,Diana Carolina Tibana Rios; Darwin Alexis Cruz García,"Realizar un acercamiento sobre la produccion bibliografica del trabajo social digital o e-social work a nivel mundial, permitio como se vera en este articulo, construir un marco de referencia sobre la cantidad y evolucion de los contenidos globales que se han realizado del tema desde un nivel cientifico. Este estudio bibliometrico retrospectivo y descriptivo de tipo documental se realizo a partir de la revision de los datos de documentos originales depositados en la base de datos Scopus y exportados a la herramienta bibliometrix version 2.2. Como hallazgos se encuentran la evolucion historica por anos, prevalencia de autores y afiliacion institucional de los mismos, concentracion por ciudad y las palabras claves. Todo lo anterior basado en los recursos de la matematica y estadistica como ejes centrales de la bibliometria.",3,4,,,,,,,,http://revista-iberoamericana.org/index.php/es/article/view/51,http://dx.doi.org/10.31876/ie.v3i4.51,,10.31876/ie.v3i4.51,3113009251,,0,,1,false,, -164-516-292-750-529,Performance analysis and scientific mapping of the literature on political marketing and brand: a systematic review,2025-01-21,2025,journal article,International Review on Public and Nonprofit Marketing,18651984; 18651992,Springer Science and Business Media LLC,Germany,Jiyoon An,,22,2,327,347,Politics; Marketing; Scientific literature; Business; Advertising; Political science; Paleontology; Law; Biology,,,,,,http://dx.doi.org/10.1007/s12208-025-00430-3,,10.1007/s12208-025-00430-3,,,0,000-626-147-242-392; 000-786-902-792-551; 000-903-096-203-31X; 001-340-266-478-499; 002-007-743-792-673; 003-266-430-581-018; 003-995-950-471-824; 005-910-295-084-365; 006-235-651-110-540; 007-767-489-154-564; 008-039-552-735-750; 009-790-113-705-514; 010-914-363-233-182; 012-019-394-854-311; 012-753-315-360-919; 013-085-095-196-429; 013-541-969-076-695; 014-605-952-121-695; 018-123-665-593-087; 025-742-133-757-454; 026-275-523-289-349; 026-668-648-509-20X; 027-411-924-984-959; 028-619-002-747-112; 030-767-657-198-018; 030-844-883-209-519; 031-870-935-983-49X; 034-060-479-521-172; 034-168-365-203-728; 035-775-213-760-040; 037-977-871-914-724; 039-594-661-223-727; 040-111-547-224-634; 040-590-429-420-766; 046-992-864-415-70X; 048-907-000-713-877; 051-623-662-247-549; 051-986-408-932-789; 056-945-897-164-426; 058-105-144-765-13X; 058-344-832-965-862; 060-110-039-971-60X; 060-784-290-267-429; 068-703-966-562-019; 070-380-396-670-55X; 071-896-715-031-530; 072-379-563-340-406; 075-399-135-489-121; 078-266-882-437-026; 078-274-569-485-259; 079-019-257-808-870; 083-213-364-729-960; 083-234-844-847-459; 083-786-824-361-879; 086-627-187-108-432; 089-425-166-943-109; 089-634-976-763-581; 091-220-617-118-419; 098-042-472-646-821; 098-377-939-800-955; 100-445-029-445-191; 102-559-603-225-328; 108-915-546-015-741; 111-340-898-772-109; 113-682-442-621-962; 120-258-053-392-677; 120-391-710-579-953; 123-130-043-513-515; 125-044-441-678-368; 125-820-496-367-857; 138-596-680-502-017; 141-026-656-461-626; 141-520-438-185-292; 142-622-084-836-716; 148-593-738-146-967; 149-228-754-084-402; 150-094-152-153-372; 150-853-958-308-921; 165-268-052-098-371; 168-819-569-583-676; 169-129-934-215-053; 172-509-256-631-033; 177-659-959-109-423; 182-931-273-166-811; 197-745-877-598-741; 198-174-424-667-601,1,false,, -164-532-317-995-072,Leadership challenges in the context of university 4.0. A thematic synthesis literature review,2021-04-12,2021,journal article,Computational and Mathematical Organization Theory,1381298x; 15729346,Springer Science and Business Media LLC,Netherlands,Álvaro Rocha; Maria José Angélico Gonçalves; Amélia Ferreira da Silva; Sandrina Teixeira; Rui Silva,,28,3,214,246,,,,,,,http://dx.doi.org/10.1007/s10588-021-09325-0,,10.1007/s10588-021-09325-0,,,0,002-052-422-936-00X; 003-924-574-057-057; 007-739-218-922-877; 007-784-645-743-26X; 013-347-232-816-266; 013-507-404-965-47X; 013-723-034-206-586; 014-246-386-515-048; 021-831-921-603-068; 024-381-811-368-152; 027-150-441-230-068; 029-557-101-745-206; 030-274-491-041-815; 033-286-722-518-455; 039-203-725-182-231; 039-309-068-404-855; 039-593-356-531-50X; 041-068-612-659-50X; 042-140-506-922-474; 049-012-192-454-37X; 050-299-752-497-017; 051-377-527-996-570; 051-975-164-698-08X; 053-368-444-829-716; 053-878-034-407-270; 056-311-394-739-991; 057-257-608-477-213; 057-445-053-583-992; 059-423-422-204-747; 061-444-671-228-533; 064-488-266-031-490; 067-546-384-039-014; 070-837-943-385-174; 071-518-195-536-659; 075-144-990-837-727; 076-337-121-474-722; 078-808-490-892-509; 080-768-432-037-596; 085-580-992-482-708; 088-242-476-046-202; 091-268-770-378-826; 092-870-965-332-965; 094-451-492-598-814; 096-936-569-210-231; 098-471-894-759-477; 098-496-740-963-10X; 107-390-229-971-232; 112-340-989-097-010; 116-953-447-460-185; 119-984-016-226-101; 121-818-154-080-049; 128-740-147-843-471; 136-036-567-993-098; 141-200-607-894-303; 143-875-130-007-110; 148-435-957-086-032; 152-420-184-690-109; 152-435-128-584-434; 153-949-230-840-558; 168-036-345-097-619; 170-744-541-853-214; 172-982-912-585-551; 179-236-365-720-012,11,false,, -164-701-413-113-791,Bibliometric analysis of a comprehensive of culture&symbol in Character animation during (2004–2024),2024-04-26,2024,preprint,,,Springer Science and Business Media LLC,,Chen Yang; Siti Salmi Jamali; Adzira Husain,"Abstract;

The analysis of academic research on animated characters in the animation industry effectively summarises the current state of scholarly research on animated characters through a variety of software tools such as CiteSpace, VOS viewer, HistCite, and Bibliometrix analysis, and visually charts and formulates this data. Through study and research, it that the United States is (278) the most prolific country, and the United States has the highest intermediary centrality, as well as the most Centre National de la Recherche Scientifique (CNRS) and PEOPLES R CHINA are the most cited organizations and Countries/Regions with the highest intermediary centrality and Countries/Regions with the highest citation explosiveness, respectively. This study also suggests possible challenges and future directions in character design for animated characters.

",,,,,Character (mathematics); Centrality; Animation; Symbol (formal); Variety (cybernetics); China; Citation; Library science; Computer science; Political science; Geography; Computer graphics (images); Archaeology; Artificial intelligence; Mathematics; Geometry; Programming language; Combinatorics,,,,,https://www.researchsquare.com/article/rs-4248138/latest.pdf https://doi.org/10.21203/rs.3.rs-4248138/v1,http://dx.doi.org/10.21203/rs.3.rs-4248138/v1,,10.21203/rs.3.rs-4248138/v1,,,0,,0,true,cc-by,green -165-020-891-075-200,Artificial Intelligence and Economic Development: An Evolutionary Investigation and Systematic Review.,2023-03-11,2023,journal article,Journal of the knowledge economy,18687873; 18687865,Springer Science and Business Media LLC,Germany,Yong Qin; Zeshui Xu; Xinxin Wang; Marinko Skare,"In today's environment of the rapid rise of artificial intelligence (AI), debate continues about whether it has beneficial effects on economic development. However, there is only a fragmented perception of what role and place AI technology actually plays in economic development (ED). In this paper, we pioneer the research by focusing our detective work and discussion on the intersection of AI and economic development. Specifically, we adopt a two-step methodology. At the first step, we analyze 2211 documents in the AI&ED field using the bibliometric tool Bibliometrix, presenting the internal structure and external characteristics of the field through different metrics and algorithms. In the second step, a qualitative content analysis of clusters calculated from the bibliographic coupling algorithm is conducted, detailing the content directions of recently distributed topics in the AI&ED field from different perspectives. The results of the bibliometric analysis suggest that the number of publications in the field has grown exponentially in recent years, and the most relevant source is the ""Sustainability"" journal. In addition, deep learning and data mining-related research are the key directions for the future. On the whole, scholars dedicated to the field have developed close cooperation and communication across the board. On the other hand, the content analysis demonstrates that most of the research is centered on the five facets of intelligent decision-making, social governance, labor and capital, Industry 4.0, and innovation. The results provide a forward-looking guide for scholars to grasp the current state and potential knowledge gaps in the AI&ED field.",15,1,1,1770,Entrepreneurship; Evolutionary economics; Economics; Management science; Neoclassical economics; Finance,Artificial intelligence; Bibliographic coupling; Bibliometrix; Content analysis; Economic development,,,national natural science foundation of china; national natural science foundation of china; fundamental research funds for the central universities; fundamental research funds for the central universities; postdoctoral research foundation of china,https://link.springer.com/content/pdf/10.1007/s13132-023-01183-2.pdf https://doi.org/10.1007/s13132-023-01183-2,http://dx.doi.org/10.1007/s13132-023-01183-2,40478928,10.1007/s13132-023-01183-2,,PMC10005923,0,001-323-429-375-458; 002-010-102-935-66X; 002-052-422-936-00X; 003-450-893-991-398; 003-914-072-470-379; 004-354-297-930-966; 004-699-406-479-929; 004-897-635-729-60X; 005-094-125-690-845; 005-633-774-377-55X; 006-239-069-656-36X; 006-420-918-875-724; 007-096-610-928-994; 009-324-128-241-291; 010-388-155-985-518; 011-169-661-253-05X; 012-723-032-580-877; 013-350-939-896-981; 013-507-404-965-47X; 013-524-854-219-241; 016-936-798-222-306; 018-003-508-224-548; 018-204-409-632-280; 019-501-046-033-20X; 023-259-871-970-916; 024-920-582-562-188; 026-877-135-106-094; 028-521-890-505-22X; 028-668-175-284-487; 030-139-354-389-282; 030-429-662-680-085; 031-291-145-474-221; 032-560-303-265-425; 032-765-827-451-279; 035-875-110-091-137; 037-394-044-243-870; 037-603-022-998-437; 038-890-123-301-468; 038-984-952-629-230; 041-821-186-114-722; 042-215-202-731-250; 044-360-454-317-703; 045-612-983-475-437; 046-424-399-301-946; 046-992-864-415-70X; 047-148-525-501-286; 048-032-375-803-28X; 049-258-675-831-918; 050-195-024-164-250; 050-391-243-355-119; 050-400-202-276-950; 051-572-926-334-535; 052-493-504-522-756; 054-018-023-034-233; 054-061-081-709-802; 054-361-221-199-563; 054-646-923-177-376; 056-200-742-345-023; 062-092-688-509-753; 063-072-799-752-594; 063-923-478-408-744; 065-668-632-570-983; 067-164-171-987-113; 068-186-579-971-960; 069-091-442-768-675; 069-758-661-058-369; 071-958-550-139-56X; 078-694-540-922-831; 079-821-815-152-748; 080-735-974-338-157; 081-090-571-877-923; 082-657-092-054-867; 083-896-411-211-618; 083-973-826-020-385; 085-972-789-780-569; 086-984-979-711-577; 091-537-698-431-444; 092-267-855-670-836; 092-877-098-359-968; 095-340-711-452-212; 095-423-269-130-774; 097-227-595-750-316; 097-757-729-859-009; 101-195-047-456-844; 102-088-531-243-659; 102-349-986-107-429; 104-047-705-982-809; 105-088-475-278-986; 106-673-033-207-500; 111-895-591-146-057; 119-537-499-451-316; 120-705-038-864-869; 121-813-144-996-86X; 122-144-357-290-941; 123-065-376-171-543; 123-106-988-796-905; 123-457-102-588-651; 127-356-760-504-467; 130-602-202-936-694; 133-205-122-832-502; 135-819-759-333-072; 136-862-023-045-836; 137-567-892-631-567; 138-398-955-256-410; 140-449-455-656-855; 142-667-368-727-326; 148-765-003-709-261; 164-875-608-502-615; 166-979-183-162-123; 168-582-450-317-992; 173-236-618-639-549; 174-700-954-197-105; 180-471-052-616-797,58,true,,bronze -165-066-109-093-93X,Scientific Literatures on Conjugated Linoleic Acid (CLA) Research in Ruminant Products: A Bibliometric Study of Evolution and Current Trends,2024-07-09,2024,journal article,Veterinary Integrative Sciences,26299968,Chiang Mai University,,Nursaadah Syahro Fitriyah; Lukman Abiola Oluodo; Patipan Hnokaew; Siriporn Umsook; Tanakorn Tanukarn; Wiphawan Kueamanee; Prayad Thirawong; Trisadee Khamlor; Saowaluck Yammuen-Art,"The objective of this study was to analyze the trends in ruminant products research (beef, goat, lamb, and milk) research, particularly conjugated linoleic acid (CLA) using intellectual and conceptual structures in bibliometric analysis. This study was conducted due to limited bibliometric articles despite the ongoing interest in the field. Data was extracted from the Scopus database and visualized using VOSviewer and the bibliometrix R package. The analysis was conducted on 2725 articles published between 2014-2024. The results indicate a decrease in the annual growth of publication in CLA research on ruminant products. Despite this decline, certain key journals persist in their role as primary references for CLA in ruminant products. The analysis revealed predominant topics such as fatty acids, meat quality, and biohydrogenation. However, certain emerging topics, including the application of particular feedstuffs and feed additives to boost fatty acids and CLA levels, have not been thoroughly investigated.",23,2,,,Ruminant; Conjugated linoleic acid; Scopus; Food science; Biotechnology; Fatty acid; Biology; Linoleic acid; Biochemistry; MEDLINE; Agronomy; Crop,,,,,,http://dx.doi.org/10.12982/vis.2025.035,,10.12982/vis.2025.035,,,0,,0,true,cc-by,gold -165-095-804-031-901,Mapping sex and gender in the landscape of spinal cord injury research: a bibliometric analysis and research framework.,2025-05-29,2025,journal article,Spinal cord,14765624; 13624393,Springer Science and Business Media LLC,United Kingdom,Stevan Stojic; Serena Affolter; Gertraud Stadler; Stacey A Missmer; Juergen Pannek; Jivko Stoyanov; Inge Eriks-Hoogland; Janina Lüscher; Marija Glisic,"Bibliometric analysis and conceptual framework.; To provide a framework for prioritizing sex/gender research in the field of spinal cord injury (SCI), which can help inform and develop future research directions benefiting both women and men affected by SCI.; Not applicable METHODS: We searched the Web of Science Core Collection to identify relevant articles. Data was analyzed using the Bibliometrix and VoSviewer tools to provide a macroscopic overview of sex/gender research trends in the field of SCI research. A framework was developed based on the results of bibliometric analyses and literature scoping, engaging professionals with backgrounds in gender medicine, translational medicine, psychology, clinical epidemiology, SCI, and endocrinology.; A total of 1031 documents were included in the analyses. We observed a steady increase in sex/gender related research from 2012, with an annual growth rate of 9.64%. Rehabilitation, epidemiology, obesity, depression, and sex hormones were identified as fundamental and critical topics for advancing sex and gender research in the context of SCI. Among a randomly selected articles, a significant proportion of studies interchangeably used the terms sex and gender. Therefore, we discuss the key overarching themes and terminology that are essential for any study exploring the relevance of sex and gender in health research. We developed a three-step research framework for considering and incorporating sex and gender in research, using SCI as a case in point.; The major principles in current paper can benefit everyone interested in studying sex/gender in the context of health in complex and disabling conditions.; © 2025. The Author(s).",,,,,,,,,,,http://dx.doi.org/10.1038/s41393-025-01089-7,40442490,10.1038/s41393-025-01089-7,,,0,003-396-679-742-521; 009-042-657-777-846; 010-654-885-607-93X; 014-897-480-375-204; 016-567-838-698-237; 020-413-495-706-647; 020-704-125-331-534; 021-486-411-421-454; 023-302-169-023-67X; 023-347-082-626-960; 025-004-984-736-569; 026-453-525-312-919; 027-709-620-663-082; 031-219-377-900-983; 031-541-994-368-078; 038-777-800-641-677; 040-320-997-176-597; 041-539-359-726-892; 042-653-211-703-067; 042-903-382-342-461; 045-499-297-619-013; 050-939-330-448-429; 051-960-966-936-965; 056-919-139-743-251; 057-137-695-656-810; 057-401-937-262-516; 073-830-059-768-366; 074-799-238-696-541; 075-819-493-894-395; 079-397-631-858-690; 079-714-991-847-502; 089-662-016-307-499; 098-737-486-418-695; 105-793-732-722-608; 113-503-861-132-817; 121-421-032-530-00X; 128-115-461-315-999; 156-401-014-796-412,0,true,cc-by,hybrid -165-270-711-306-326,Replication Data for: Research trends of vitamin D metabolism gene polymorphisms based on a bibliometric investigation,2023-01-01,2023,dataset,Harvard Dataverse,,,,Mohamed Abouzid; Marta Karaźniewicz-Łada; Basel Abdelazeem; James Robert Brašić,"Combined raw data used for CiteSpace©, Bibliometrix©, and VOSviewer© to create the bibliometric map and cluster timeline",,,,,Replication (statistics); Gene; Computational biology; Genetics; Biology; Bioinformatics; Data science; Computer science; Virology,,,,,https://dataverse.harvard.edu/citation?persistentId=doi:10.7910/DVN/BQGSYI,http://dx.doi.org/10.7910/dvn/bqgsyi,,10.7910/dvn/bqgsyi,,,0,,0,true,other-oa,gold -165-346-645-505-404,Research dynamics and drug treatment of renal fibrosis from a mitochondrial perspective: a historical text data analysis based on bibliometrics.,2025-04-14,2025,journal article,Naunyn-Schmiedeberg's archives of pharmacology,14321912; 00281298,Springer Science and Business Media LLC,Germany,Xu Li; Lan Hu; Qin Hu; Hua Jin,,,,,,Bibliometrics; Perspective (graphical); Field (mathematics); Dynamics (music); Medicine; Data science; Computer science; Sociology; Library science; Artificial intelligence; Mathematics; Pedagogy; Pure mathematics,Bibliometrics; Mitochondria; Renal fibrosis; Visual analysis,,,National Natural Science Foundation of China (82274307); Research Funds of Center for Xin'an Medicine and Modernization of Traditional Chinese Medicine of IHM (2023CXMMTCM018),,http://dx.doi.org/10.1007/s00210-025-04151-6,40229603,10.1007/s00210-025-04151-6,,,0,000-929-499-540-842; 001-977-554-044-108; 002-052-422-936-00X; 002-140-146-066-57X; 003-192-750-029-565; 003-463-857-266-829; 004-995-803-200-596; 006-640-885-278-88X; 010-883-641-749-498; 012-832-716-450-152; 013-507-404-965-47X; 016-724-269-129-152; 022-217-418-157-677; 023-221-775-015-456; 025-094-520-005-372; 025-824-143-908-307; 026-771-681-141-254; 030-238-067-008-591; 030-549-357-540-357; 034-256-549-584-369; 035-246-427-013-59X; 035-251-945-759-793; 036-266-413-239-330; 036-786-469-910-794; 043-331-600-313-753; 048-849-101-291-754; 048-853-598-940-757; 052-955-327-714-477; 055-060-206-972-287; 055-244-828-263-019; 058-547-239-254-445; 067-928-016-835-66X; 072-852-328-515-190; 074-318-387-765-299; 076-696-067-503-960; 078-058-292-396-141; 083-210-307-796-91X; 086-939-546-545-195; 090-476-872-676-699; 091-176-303-814-838; 091-783-984-990-267; 094-650-660-335-776; 098-668-746-588-847; 098-878-901-020-211; 105-183-375-525-834; 115-907-779-158-544; 117-952-309-655-082; 122-086-139-662-425; 124-937-022-881-785; 127-368-584-675-563; 133-316-542-479-807; 137-356-231-171-081; 141-770-516-078-794; 143-785-133-011-570; 147-612-046-354-68X; 148-246-174-854-848; 154-029-636-229-278; 154-848-795-688-868; 157-935-028-725-204; 190-958-425-599-49X; 192-576-906-486-460; 192-741-017-496-729; 199-341-735-524-431,0,false,, -165-389-169-489-350,Evolution of artificial intelligence in medical sciences: a comprehensive scientometrics analysis,2025-03-27,2025,journal article,"Global Knowledge, Memory and Communication",25149342; 25149350,Emerald,,Mostafa Kashani; Meisam Dastani,"Purpose; The purpose of this study is to analyze the trend of scientific publications, geographic and organizational distribution, and examine the keyword cooccurrence map in the field of artificial intelligence (AI) in medical sciences.; ; Design/methodology/approach; The applied research has used the scientometrics method to analyze data to AI in medical sciences. The data were extracted from the WOSCC database. Data analysis was performed using the bibliometrix software.; ; Findings; According to the results, 41,352 scientific documents in the field of AI in medical sciences were extracted, the growth trend of which has increased significantly since 2000. The USA, China and England were identified as leaders in this field, and universities, such as Harvard University and the University of California, contributed the most to related knowledge production. Moreover, the terms “machine learning” and “deep learning” have been proposed as key concepts in this field.; ; Practical implications; The findings of this study highlight the significant role of AI in advancing medical research and healthcare systems. By fostering international collaboration and focusing on emerging trends, the integration of AI can lead to improved healthcare outcomes and the development of innovative solutions that address pressing medical challenges.; ; Originality/value; This research contributes to the existing body of knowledge by providing a comprehensive analysis of the trends, geographic distribution and key concepts associated with AI in medical sciences. By using scientometric methods and bibliometrix software, this study offers a unique perspective on the evolution of AI research within the medical field, identifying leading institutions and pivotal concepts such as “machine learning” and “deep learning.”; ",,,,,Scientometrics; Medical science; Data science; Computer science; Library science; Medicine; Medical education,,,,,,http://dx.doi.org/10.1108/gkmc-09-2024-0586,,10.1108/gkmc-09-2024-0586,,,0,000-096-142-707-44X; 002-132-814-055-025; 003-933-561-205-246; 004-608-404-207-368; 013-507-404-965-47X; 015-857-923-685-296; 023-676-613-522-739; 026-466-816-212-136; 027-513-097-536-497; 028-068-855-279-957; 028-219-218-402-655; 029-503-214-072-390; 030-654-902-344-47X; 033-891-292-808-57X; 038-699-047-832-404; 042-782-899-994-261; 046-623-813-885-978; 050-133-986-046-200; 052-412-091-375-489; 069-820-844-238-164; 070-248-168-574-808; 075-202-646-599-478; 076-502-961-510-243; 083-693-775-523-882; 094-393-232-914-996; 104-376-444-572-656; 104-645-510-450-546; 107-518-655-388-824; 115-368-392-162-389; 125-198-544-093-719; 158-985-590-374-79X; 188-473-335-932-642; 196-393-338-865-262,0,false,, -165-615-539-146-391,Research trends in vascular chips from 2012 to 2022: a bibliometrix and visualized analysis.,2024-07-11,2024,journal article,Frontiers in bioengineering and biotechnology,22964185,Frontiers Media SA,Switzerland,Song Yang; Jing Luo; Wanwan Zou; Qikun Zhu; Jianzheng Cen; Qiang Gao,"The vascular chip has emerged as a significant research tool, garnering increasing interest and exploration. We utilize bibliometric techniques to analyze literature from the Web of Science (WOS) database, focusing on core journal publications. The aim is to provide a systematic review and prospective outlook on research trends within the vascular chip field, delving into current dynamics and highlighting areas for further investigation.; We retrieved articles, proceedings papers, and early-access publications related to vascular chips published between January 2012 and December 2022 reported by Web of Science Core Collection (WoSCC) in 2023. Scientific bibliometric analysis was performed using R-bibliometrix, CiteSpace, VOSviewer, and Microsoft Excel software tools.; A total of 456 publications were obtained, including 444 articles, 11 proceedings papers, and one early-access article. These originated from 167 academic journals and 751 research institutions across 44 countries/regions. The United States contributed the majority of publications (41%), with Harvard University leading in contributions (6.6%). Lab on a Chip was the top journal in terms of publications. Notably, authors Jeon NL and Huh D wielded significant influence, with the former being the most prolific author and the latter garnering the most citations. Recent research has predominantly focused on angiogenesis in relation to endothelial cells.; This scientometric investigation comprehensively surveys literature on vascular chips over past decade, providing valuable insights for scholars in the field. Our study reveals global increases in publications, with endothelial cells and angiogenesis being primary research focuses. This trend will persist, drawing continued attention from researchers.; Copyright © 2024 Yang, Luo, Zou, Zhu, Cen and Gao.",12,,1409467,,Web of science; Library science; Bibliometrics; Impact factor; Political science; Data science; Computer science; MEDLINE; Law,CiteSpace; VOSviewer; angiogenesis; bibliometric analysis; endothelial cells; vascular chip,,,,https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2024.1409467/pdf https://doi.org/10.3389/fbioe.2024.1409467,http://dx.doi.org/10.3389/fbioe.2024.1409467,39055344,10.3389/fbioe.2024.1409467,,PMC11269249,0,003-863-621-094-621; 005-011-636-083-514; 005-681-238-073-452; 007-468-140-720-332; 016-322-348-644-230; 018-557-797-782-54X; 028-056-254-346-298; 029-812-207-460-407; 031-695-412-548-768; 034-901-400-088-550; 037-670-095-410-948; 040-309-520-228-102; 044-168-634-148-281; 053-625-675-313-324; 055-018-756-236-496; 055-197-377-990-962; 064-212-661-856-102; 064-716-380-125-468; 076-196-806-192-22X; 078-043-913-735-643; 092-856-554-600-602; 098-761-525-976-885; 161-987-855-904-950; 195-471-174-668-32X,2,true,cc-by,gold -165-729-320-169-981,Bibliometric data,2021-01-01,2021,dataset,Figshare,,,,Kara C. Hoover,"The single file containing all the results of the Web of Science search used in analyzing data in R (bibliometrix package) can also be imported into most reference management software (e.g., Zotero, Endnote) or viewed in a text editor (e.g., bibtex, textpad)
",,,,,Geography,,,,,https://figshare.com/articles/dataset/Bibliometric_data/16864297,http://dx.doi.org/10.6084/m9.figshare.16864297,,10.6084/m9.figshare.16864297,,,0,,0,true,cc-by,gold -165-755-078-767-084,Mapping the Trends in Global Research Productivity and Conservation of Saffron (Crocus sativus L.): Insight from Bibliometric Analysis during 1950–2022,2024-02-20,2024,journal article,Biology Bulletin Reviews,20790864; 20790872,Pleiades Publishing Ltd,,M. Sharma; D. Sharma; S. C. Sahu; A. Sharma; M. Sharma,,14,2,238,250,Crocus sativus; Cash crop; Globe; Web of science; Biology; Traditional medicine; Data science; Computer science; Botany; Ecology; Agriculture; MEDLINE; Medicine; Biochemistry; Neuroscience,,,,,,http://dx.doi.org/10.1134/s2079086424020117,,10.1134/s2079086424020117,,,0,001-497-553-816-45X; 003-310-656-958-813; 009-692-097-435-091; 013-358-678-935-028; 017-434-927-015-853; 029-537-575-235-04X; 029-630-611-756-819; 035-953-531-599-220; 038-605-933-207-769; 039-891-106-904-102; 042-499-744-660-984; 046-992-864-415-70X; 049-935-013-365-001; 052-959-639-239-087; 064-742-234-216-07X; 072-358-794-691-198; 088-394-321-455-354; 089-241-293-864-917; 094-742-816-778-88X; 104-614-300-019-836; 104-767-754-326-686; 108-985-325-768-946; 129-565-341-822-085; 146-365-813-872-567,3,false,, -165-808-075-484-042,PATENT ANALYSIS: AN APPROACH USING BIBLIOMETRIX.,2023-02-28,2023,conference proceedings article,19th CONTECSI International Conference on Information Systems and Technology Management,,TECSI,,Eduardo Amadeu Dutra Moresi; isabel Pinho,"Patent application documents are systematically collected in a structured data format (including application date, applicant and inventor name, and a complete technical description of the invention) in publicly available patent databases. The purpose of this paper is to present a guide that exploits the bibliometric analysis capabilities available in the R-Bibliometrix package for patent analysis. This objective will broaden the understanding of quantitative results and allow further interpretation of research findings from selected documents by means of bibliometric metrics. Therefore, the purpose of this work is to answer the following research question: how to employ bibliometric analysis in the interpretation of documents retrieved in searches carried out in patent databases? A search was conducted in the Lens database, which is open access, on the topic of virtual worlds. The application of the approach allowed us to identify some performance indicators and to trace a technological map, including the annual evolution of patent production; the quantity of documents per jurisdiction; the main patent owners; the main inventors and their institutions; the inventors' production in the period 2006 to 2022; the most frequent keywords extracted from the abstracts; the most frequent CPC class codes; the technological trends from the CPC subclasses; the thematic maps, and the evolution of the technological structure of the CPC subclasses and the bigrams extracted from the abstracts. It's concluded by highlighting the potential of the R-Bibliometrix package for patent analysis to identify performance indicators and perform technological mapping. Os documentos de pedido de patente são sistematicamente coletados em um formato de dados estruturados (incluindo data do pedido, nome do depositante e do inventor, e uma descrição técnica completa da invenção) em bancos de dados de patentes disponíveis ao público. O propósito deste trabalho é apresentar um guia que explore as potencialidades de análise bibliométrica disponíveis no pacote R-Bibliometrix para a análise de patentes. Este objetivo irá ampliar o entendimento dos resultados quantitativos e permitir aprofundar a interpretação dos resultados da pesquisa a partir de documentos selecionados por meio de métricas bibliométricas. Portanto, a proposta deste trabalho é responder a seguinte questão de pesquisa: como empregar a análise bibliométrica na interpretação de documentos recuperados em pesquisas realizadas em bases de patentes? Foi realizada uma pesquisa na base Lens, que é de acesso livre, sobre o tema mundos virtuais. A aplicação da abordagem permitiu identificar alguns indicadores de desempenho e traçar um panorama tecnológico do tema, incluindo a evolução anual da produção de patentes, os quantitativos de documentos por jurisdição, os principais detentores de patentes, os principais inventores com os respetivos vínculos institucionais, a produção dos inventores no período de 2006 a 2022, as palavras-chave mais frequentes extraídas dos resumos, os códigos das classes CPC mais frequentes, as tendências tecnológicas a partir das subclasses CPC, os mapas temáticos e as evoluções da estrutura tecnológica das subclasses CPC e dos bigramas extraídos dos resumos. Conclui-se ressaltando as potencialidades do pacote R-Bibliometrix para a análise de patentes visando identificar indicadores de desempenho e realizar o mapeamento tecnológico.",,,,,Computer science; Patent analysis; Interpretation (philosophy); Information retrieval; Data science; Patent visualisation; Programming language,,,,,https://www.tecsi.org/contecsi/index.php/contecsi/19CONTECSI/paper/download/6962/4563 https://doi.org/10.5748/19contecsi/pse/itm/6962,http://dx.doi.org/10.5748/19contecsi/pse/itm/6962,,10.5748/19contecsi/pse/itm/6962,,,0,,1,true,cc-by,hybrid -166-063-135-495-468,Global research trends in tongue cancer from 2000 to 2022: bibliometric and visualized analysis.,2024-02-02,2024,journal article,Clinical oral investigations,14363771; 14326981,Springer Science and Business Media LLC,Germany,Beibei Wu; Tong Zhang; Ning Dai; Ding Luo; Xuejie Wang; Chen Qiao; Jian Liu,,28,2,130,,Cancer; Tongue; Bibliometrics; Medicine; China; Library science; Family medicine; Geography; Pathology; Internal medicine; Computer science; Archaeology,Bibliometrics; Data visualization; Hotspots; Research status; Tongue cancer,Humans; Tongue Neoplasms/therapy; Papillomavirus Infections; Mouth Neoplasms; Tongue; Bibliometrics,,,,http://dx.doi.org/10.1007/s00784-024-05516-6,38305810,10.1007/s00784-024-05516-6,,,0,000-649-117-467-373; 001-862-770-295-462; 003-327-323-321-313; 004-184-611-116-710; 006-824-107-153-024; 006-888-951-152-345; 007-687-022-805-976; 008-512-541-808-257; 010-222-061-613-641; 010-247-264-802-013; 012-029-512-740-470; 012-625-205-505-375; 013-140-092-379-587; 015-488-678-835-674; 015-618-804-112-18X; 018-461-535-537-118; 020-169-667-459-83X; 020-530-529-955-274; 020-964-978-939-489; 022-928-049-364-144; 023-674-732-533-597; 024-191-899-847-66X; 026-583-818-777-547; 027-774-722-231-695; 029-643-276-811-915; 032-558-495-938-360; 037-147-247-064-68X; 039-170-571-237-923; 041-861-499-487-884; 043-167-728-239-028; 043-315-727-287-126; 046-210-631-497-530; 046-545-130-829-538; 048-241-207-307-130; 049-867-608-561-237; 050-165-335-081-914; 055-857-165-557-244; 061-083-085-482-730; 064-401-288-212-159; 065-434-130-549-170; 067-899-562-673-469; 071-067-190-056-963; 071-985-543-971-79X; 072-959-637-187-768; 074-217-814-006-72X; 075-368-274-828-224; 076-471-066-011-609; 078-578-406-871-545; 079-614-235-506-990; 080-082-500-754-946; 081-026-224-007-652; 093-405-960-173-312; 097-440-143-961-131; 101-062-525-131-034; 107-715-674-239-229; 108-678-029-916-983; 111-696-125-698-426; 114-586-823-433-654; 118-796-076-412-817; 153-399-148-842-26X; 156-357-632-285-892; 185-741-230-902-358,4,false,, -166-139-790-924-394,A bibliometric analysis of cultural heritage visualisation based on Web of Science from 1998 to 2023: a literature overview,2024-08-24,2024,journal article,Humanities and Social Sciences Communications,26629992,Springer Science and Business Media LLC,,Yuchen Tang; Liu Liu; Tianbo Pan; Zhangxu Wu,"AbstractCultural heritage visualisation research is a vast and constantly evolving field full of energy. It is concerned with the conservation, exhibition and education of cultural heritage. Plenty of studies have been reported, while more general bibliometric research is lacking. Thus, this study analyses, quantifies and maps the cultural heritage visualisation research from 1998 to 2023 using the Web of Science (WOS) core database. Biblioshiny was used to classify and evaluate the contributions of authors, countries, topics and journals. In addition, VOSviewer was used for the visual presentation of keywords. The results show that the hotspots of cultural heritage visualisation research are 3D modelling and digital management. Such techniques have become increasingly important and prevalent in the field of cultural heritage, with a multitude of activities. The study also makes predictions about how the future of cultural heritage visualisation will change, including a larger range of applications and cross-border collaboration across various disciplines. Therefore, this study provides a relatively new perspective through which more research directions can be found for the exploitation of cultural heritage conservation.",11,1,,,Cultural heritage; Visualization; Web of science; Data science; Computer science; World Wide Web; Library science; Geography; Archaeology; Political science; MEDLINE; Data mining; Law,,,,,,http://dx.doi.org/10.1057/s41599-024-03567-4,,10.1057/s41599-024-03567-4,,,0,000-649-102-517-980; 001-224-229-222-963; 001-804-466-599-220; 007-286-611-839-392; 009-512-155-962-041; 010-942-996-569-370; 012-830-222-044-411; 013-507-404-965-47X; 014-865-405-102-71X; 016-028-508-474-713; 017-680-395-923-677; 023-013-987-872-410; 023-500-567-219-755; 023-768-167-500-449; 026-835-257-948-884; 028-153-066-394-932; 029-823-111-770-13X; 034-527-375-835-907; 034-768-039-318-254; 041-703-664-228-875; 044-147-544-148-875; 046-663-050-789-123; 046-992-864-415-70X; 048-216-137-471-159; 052-518-804-805-510; 053-880-828-029-905; 054-396-203-988-251; 058-508-399-333-343; 060-323-682-838-735; 064-493-813-370-798; 065-026-194-566-751; 065-264-885-007-91X; 065-981-324-807-003; 073-225-169-224-970; 078-222-517-617-50X; 082-622-068-112-940; 082-951-243-906-500; 084-402-897-466-752; 092-337-413-719-20X; 092-843-483-914-432; 092-946-192-494-951; 094-584-480-497-433; 096-031-767-202-21X; 109-024-188-129-403; 126-359-545-858-585; 126-444-743-349-382; 128-201-504-791-76X; 133-984-947-356-761; 136-958-876-290-119; 137-024-144-148-173; 141-968-824-482-215; 142-701-225-454-734; 144-366-994-796-47X; 150-222-416-550-595; 151-159-477-014-312; 159-899-846-440-443; 177-681-883-631-792; 199-810-681-206-989,2,true,cc-by,gold -166-197-745-951-903,Rising utilization of stable isotopes in tree rings for climate change and forest ecology,2023-12-07,2023,journal article,Journal of Forestry Research,1007662x; 19930607; 10025618,Springer Science and Business Media LLC,United States,Ru Huang; Chenxi Xu; Jussi Grießinger; Xiaoyu Feng; Haifeng Zhu; Achim Bräuning,"AbstractAnalyses of stable isotopes (C, O, H) in tree rings are increasingly important cross-disciplinary programs. The rapid development in this field documented in an increasing number of publications requires a comprehensive review. This study includes a bibliometric analysis-based review to better understand research trends in tree ring stable isotope research. Overall, 1475 publications were selected from the Web of Science Core Collection for 1974–2023. The findings are that: (1) numbers of annual publications and citations increased since 1974. From 1974 to 1980, there were around two relevant publications per year. However, from 2020 to 2022, this rose sharply to 109 publications per year. Likewise, average article citations were less than four per year before 1990, but were around four per article per year after 2000; (2) the major subjects using tree ring stable isotopes include forestry, geosciences, and environmental sciences, contributing to 42.5% of the total during 1974–2023; (3) the top three most productive institutions are the Chinese Academy of Sciences (423), the Swiss Federal Institute for Forest, Snow and Landscape Research (227), and the University of Arizona (204). These achievements result from strong collaborations; (4) review papers, for example, (Dawson et al., Annu Rev Ecol Syst 33:507–559, 2002) and (McCarroll and Loader, Quat Sci Rev 23:771–801, 2004), are among the most cited, with more than 1000 citations; (5) tree ring stable isotope studies mainly focus on climatology and ecology, with atmospheric CO2 one of the most popular topics. Since 2010, precipitation and drought have received increasing attention. Based on this analysis, the research stages, key findings, debated issues, limitations and directions for future research are summarized. This study serves as an important attempt to understand the progress on the use of stable isotopes in tree rings, providing scientific guidance for young researchers in this field.",35,1,,,Dendrochronology; Stable isotope ratio; Ecology; Climate change; Environmental science; Physical geography; Geography; Forestry; Biology; Archaeology; Physics; Quantum mechanics,,,,,https://link.springer.com/content/pdf/10.1007/s11676-023-01668-5.pdf https://doi.org/10.1007/s11676-023-01668-5,http://dx.doi.org/10.1007/s11676-023-01668-5,,10.1007/s11676-023-01668-5,,,0,000-107-095-443-779; 000-179-203-130-140; 000-534-823-238-674; 004-752-323-507-373; 006-395-783-644-432; 006-874-203-030-150; 007-727-345-764-930; 008-446-021-280-046; 010-250-201-676-328; 010-424-211-698-309; 011-075-791-103-749; 013-507-404-965-47X; 014-642-394-494-536; 015-100-423-205-159; 017-896-355-595-763; 018-779-059-835-340; 019-534-609-773-633; 020-349-913-765-284; 020-596-703-248-201; 021-001-277-372-058; 021-375-917-426-744; 024-092-334-275-189; 027-571-578-225-492; 030-581-505-983-273; 030-639-369-488-970; 031-291-205-252-234; 032-883-887-511-023; 037-261-069-430-163; 038-047-703-194-276; 038-592-863-608-611; 041-118-113-085-954; 046-136-249-553-877; 046-295-930-627-150; 046-877-068-029-441; 048-260-327-787-814; 048-448-361-421-829; 050-519-280-225-33X; 051-606-801-610-180; 055-080-163-803-915; 055-345-864-317-339; 055-497-099-256-606; 060-697-446-585-306; 060-784-969-833-909; 060-917-166-711-963; 061-056-027-650-755; 061-219-061-502-91X; 063-947-913-265-36X; 065-689-188-305-552; 065-794-461-243-247; 065-893-678-385-493; 066-548-765-065-112; 066-684-842-785-743; 067-290-048-413-701; 068-088-171-175-312; 069-428-611-092-17X; 070-545-073-050-172; 070-974-063-564-95X; 072-295-688-244-41X; 072-308-991-604-019; 074-893-039-602-638; 075-248-169-129-169; 075-292-158-178-094; 075-591-644-409-660; 076-443-379-284-757; 076-977-162-338-984; 077-583-880-560-55X; 089-244-296-776-780; 089-786-995-754-157; 090-842-234-767-198; 093-963-103-784-502; 094-975-463-901-009; 095-228-570-404-435; 096-116-568-434-790; 096-446-437-700-333; 096-649-248-689-956; 102-129-872-362-478; 104-252-746-494-628; 105-217-659-041-754; 106-586-714-433-399; 109-305-986-470-746; 114-614-619-373-24X; 117-577-897-681-41X; 119-634-593-450-509; 121-031-484-751-432; 121-233-282-613-467; 124-219-152-285-731; 125-650-733-119-875; 127-696-906-945-347; 133-835-836-575-938; 134-064-520-539-942; 137-041-259-640-111; 141-749-499-090-68X; 146-594-974-690-026; 147-573-995-598-425; 154-798-542-064-35X; 158-397-000-882-68X; 164-441-706-689-163; 165-983-812-139-846; 167-359-499-754-300; 169-177-043-292-959; 169-792-186-253-433; 173-634-250-177-879; 181-935-365-477-184; 183-043-485-442-516; 184-902-655-500-491; 193-284-826-926-800; 195-216-354-012-063,6,true,cc-by,hybrid -166-246-987-422-391,Advancing lignocellulosic biomass pretreatment with nanotechnology: a comprehensive bibliometric analysis,2025-02-03,2025,journal article,Cellulose,09690239; 1572882x,Springer Science and Business Media LLC,United Kingdom,Humna Shakeel; Kiran Aftab; Fakiha Tul Jannat; Faiza Amin; Huma Umbreen; Razia Noreen,,32,4,2167,2193,Lignocellulosic biomass; Biomass (ecology); Nanotechnology; Materials science; Biochemical engineering; Biotechnology; Biofuel; Engineering; Biology; Agronomy,,,,,,http://dx.doi.org/10.1007/s10570-025-06403-3,,10.1007/s10570-025-06403-3,,,0,001-669-231-161-946; 004-445-373-461-625; 004-739-011-211-550; 007-556-041-402-195; 007-775-135-141-408; 008-398-522-745-338; 010-680-039-271-460; 010-769-863-008-012; 012-565-680-898-583; 013-507-404-965-47X; 013-798-741-818-473; 014-338-603-327-982; 015-051-265-319-522; 015-344-701-998-963; 015-433-335-224-806; 017-241-610-383-42X; 020-418-826-330-123; 020-654-920-309-691; 022-123-381-722-443; 026-150-747-072-481; 026-165-559-539-664; 027-195-811-684-307; 030-472-317-158-53X; 031-123-170-886-639; 031-571-484-113-312; 038-062-135-356-083; 040-707-424-851-774; 044-864-358-474-214; 046-162-712-474-644; 046-992-864-415-70X; 047-516-542-479-697; 049-303-021-622-340; 049-391-379-302-694; 050-110-317-801-131; 051-542-924-429-146; 051-925-602-990-65X; 053-623-911-515-405; 054-730-503-972-113; 055-044-879-607-778; 056-840-965-439-700; 058-987-207-220-709; 059-766-711-792-412; 060-412-380-981-821; 061-812-303-140-657; 069-297-150-727-20X; 073-379-605-124-426; 078-483-215-820-460; 082-035-833-050-809; 083-875-897-439-184; 090-507-795-421-13X; 091-847-271-812-030; 093-754-782-473-958; 097-910-165-008-548; 099-987-263-330-176; 100-124-039-362-915; 101-105-589-039-082; 101-199-388-979-852; 104-485-214-161-07X; 105-450-885-061-949; 105-701-468-459-300; 108-314-883-211-475; 111-828-279-614-311; 111-965-709-992-779; 113-054-633-200-450; 114-864-841-759-903; 116-402-986-029-182; 118-130-046-847-78X; 120-458-845-119-763; 125-785-322-188-84X; 133-301-185-933-669; 135-284-402-435-57X; 135-629-788-506-166; 136-869-484-044-90X; 137-016-049-992-376; 140-258-630-010-874; 140-527-722-318-73X; 143-845-097-252-175; 144-735-574-287-442; 146-716-558-447-652; 150-052-680-955-728; 151-232-532-271-484; 153-497-788-303-79X; 156-973-401-327-556; 166-550-181-424-933; 167-775-884-984-826; 170-698-933-138-813; 171-066-861-052-084; 174-504-780-652-519,1,false,, -166-470-680-253-227,"Analysis of Trends in the Application of Augmented Reality in Students with ASD: InTellectual, Social and Conceptual Structure of Scientific Production Through WOS and Scopus",2022-01-15,2022,journal article,"Technology, Knowledge and Learning",22111662; 22111670,Springer Science and Business Media LLC,United States,G. Lorenzo; A. Gilabert; A. Lledó; A. Lorenzo-Lledó,,,,,,Scopus; Field (mathematics); Citation; Web of science; Computer science; Inclusion (mineral); Bibliometrics; Thematic map; Data science; Sociology; Social science; World Wide Web; Geography; Mathematics; Political science; MEDLINE; Cartography; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1007/s10758-021-09582-7,,10.1007/s10758-021-09582-7,,,0,001-995-546-325-363; 002-974-785-456-313; 004-526-996-499-19X; 004-637-359-526-978; 005-611-357-705-527; 007-352-642-902-502; 008-921-409-492-440; 010-065-762-504-134; 010-194-028-604-828; 010-535-361-655-568; 013-507-404-965-47X; 013-524-854-219-241; 014-344-166-117-362; 018-016-514-072-15X; 019-833-056-876-383; 021-994-249-735-471; 027-987-380-969-743; 030-228-039-525-365; 030-275-029-564-880; 030-647-174-824-057; 031-531-051-422-754; 031-804-788-708-301; 036-900-819-515-222; 037-364-464-123-085; 039-802-397-581-739; 040-156-483-462-842; 044-151-611-794-538; 045-422-273-148-899; 045-538-349-555-146; 045-950-130-994-667; 046-992-864-415-70X; 048-534-769-496-550; 054-439-051-844-343; 055-069-593-800-960; 057-803-697-074-453; 061-202-126-245-002; 061-318-171-544-41X; 067-516-779-199-031; 067-888-425-118-596; 069-511-868-544-95X; 070-978-717-326-853; 073-367-985-641-83X; 074-322-442-712-977; 075-256-584-700-852; 076-743-812-973-583; 076-881-387-277-91X; 088-027-930-564-703; 089-315-825-985-779; 096-061-214-240-715; 100-285-851-460-652; 101-201-232-713-249; 104-919-753-218-202; 108-793-332-183-675; 119-852-264-234-691; 120-974-286-046-262; 122-415-544-444-960; 124-585-524-209-757; 124-915-980-540-880; 131-423-542-523-282; 148-139-343-889-889; 159-146-750-944-499; 162-123-368-418-70X; 168-422-520-922-07X; 174-026-171-277-238; 177-882-177-384-49X; 196-795-166-914-014,5,false,, -166-491-063-224-407,Performance indicators and maintenance management: scientific mapping,2025-01-22,2025,journal article,Scientia cum Industria,23185279,Universidade Caxias do Sul,,Rogerio Cabral dos Anjos; Ana Caroline Dzulinski; Lucas Schmidt Goecks,"The versatility of Industrial Engineering means that professionals face productivity and efficiency challenges in different types and sizes of organizations. To deal with these challenges, practical tools for process optimization are needed, such as Overall Equipment Effectiveness (OEE) and Total Productive Maintenance (TPM), which are highly relevant due to their versatility. In this context, this work aims to research, organize, quantify, and discuss scientific articles in a theoretical review covering the topics of OEE and TPM, considering the large volume of scientific production on these topics. The research was conducted through a Systematic Literature Review that involved searching scientific databases and using the Bibliometrix software and its Biblioshiny extension to construct a scientific mapping. Additionally, a qualitative analysis of the article data was carried out to understand, discuss, and relate the data with scientific mapping, obtaining results on the main keywords, the leading countries with scientific production, the highlighted journals, the impact factor, and correlations between them. ",14,1,e251401,e251401,Computer science,,,,,,http://dx.doi.org/10.18226/23185279.e251401,,10.18226/23185279.e251401,,,0,,0,true,,bronze -166-661-776-836-891,A bibliometric analysis of rheumatology: knowledge structure and research trends of RNA-Binding proteins in rheumatic diseases.,2025-04-30,2025,journal article,Clinical rheumatology,14349949; 07703198,Springer Science and Business Media LLC,Germany,Wei Zhang; Jiaqi Song; Shuyuan Xian; Sujie Xie; Yifan Liu; Yuntao Yao; Xirui Tong; Xinru Wu; Yuanan Li; Haoyu Zhang; Bingnan Lu; Jiajie Zhou; Yibin Zhou; Dayuan Xu; Runzhi Huang; Shizhao Ji,,44,6,2501,2516,Rheumatology; Medicine; Internal medicine; Computational biology; Bioinformatics; Medical physics; Biology,Bibliometrics; RNA-binding proteins (RBPs); Rheumatic diseases; Rheumatology,Humans; Bibliometrics; Rheumatic Diseases/metabolism; Rheumatology/trends; RNA-Binding Proteins/metabolism; Biomedical Research/trends,RNA-Binding Proteins,National Natural Science Foundation of China (81971836); Shanghai Rising-Star Program (Sailing Special Program) (No. 23YF1458400); Program of Shanghai Academic Research Leader (23XD1425000),,http://dx.doi.org/10.1007/s10067-025-07403-1,40307540,10.1007/s10067-025-07403-1,,,0,000-437-246-203-943; 000-850-357-526-269; 002-052-422-936-00X; 002-186-434-569-626; 002-951-366-569-266; 004-565-248-115-981; 007-255-287-048-238; 007-512-509-973-547; 008-222-427-800-520; 013-507-404-965-47X; 014-788-882-152-895; 015-082-882-262-113; 015-485-493-898-675; 015-794-139-091-595; 016-293-438-328-434; 016-478-503-681-041; 017-663-648-485-405; 018-089-477-290-672; 018-478-883-712-542; 018-548-258-123-807; 021-815-943-505-696; 025-277-947-572-458; 028-011-580-281-806; 028-153-066-394-932; 031-258-572-749-408; 032-410-038-423-90X; 033-127-677-566-360; 033-354-752-758-945; 038-809-589-544-575; 042-474-047-254-816; 048-796-453-537-950; 056-648-762-772-730; 063-541-789-015-119; 064-400-499-357-900; 071-145-819-645-599; 080-977-108-232-315; 090-706-232-527-709; 100-444-159-623-481; 101-752-490-869-458; 110-582-818-385-033; 119-559-534-041-10X; 130-651-689-902-445; 164-949-297-321-17X,0,false,, -166-759-935-534-803,"A bibliometric analysis of research on asphalt aging: trends, patterns, and impact",2024-11-05,2024,journal article,Journal of Building Pathology and Rehabilitation,23653159; 23653167,Springer Science and Business Media LLC,,Muhammad Ibrahim Khalili Bin Abd Rahim; Haryati Yaacob; Muhammad Naqiuddin Bin Mohd Warid; Mohd Khairul Afzan Bin Mohd Lazi; Nor Zurairahetty Binti Mohd Yunus; Christiana Adebola Odubela; Norzita Ngadi; Ekarizan Shaffie; Ramadhansyah Putra Jaya; Zaid Hazim Al-Saffar,,10,1,,,Asphalt; Bibliometrics; Regional science; Geography; Computer science; Library science; Cartography,,,,"Ministry of Higher Education, Malaysia; Ministry of Higher Education, Malaysia",,http://dx.doi.org/10.1007/s41024-024-00533-0,,10.1007/s41024-024-00533-0,,,0,000-692-431-479-94X; 002-645-331-168-74X; 006-009-236-856-93X; 006-739-469-048-559; 009-047-001-356-849; 010-309-302-677-702; 010-647-730-203-687; 010-681-934-997-668; 013-507-404-965-47X; 014-220-076-744-923; 015-341-734-360-233; 015-345-772-383-717; 015-995-008-154-905; 016-020-079-845-603; 016-642-629-599-109; 016-689-944-232-866; 017-462-853-180-490; 017-765-487-592-046; 020-068-469-094-38X; 021-084-048-567-587; 026-025-137-583-468; 027-165-411-378-91X; 027-690-220-065-414; 028-344-340-510-388; 030-070-985-228-781; 030-563-214-535-308; 031-115-465-433-864; 031-797-998-588-595; 033-768-360-818-734; 033-994-728-920-661; 034-346-739-588-896; 037-900-565-151-567; 039-283-048-041-388; 039-721-953-225-061; 039-916-632-139-728; 040-135-110-049-120; 040-147-404-607-798; 042-028-363-261-196; 044-526-098-169-309; 045-257-572-891-854; 045-872-051-830-903; 049-263-604-729-98X; 049-317-090-171-712; 049-587-365-375-918; 050-308-509-649-246; 051-263-786-139-236; 053-570-663-810-918; 054-520-800-663-469; 055-263-149-191-707; 056-669-075-817-40X; 058-151-896-168-431; 061-606-151-890-661; 061-687-926-442-299; 062-752-172-785-66X; 064-619-520-365-224; 064-697-176-438-968; 065-613-827-257-710; 067-415-204-324-855; 075-459-703-231-383; 076-248-519-664-441; 078-832-571-030-02X; 079-092-587-829-480; 079-388-047-650-212; 080-735-974-338-157; 087-480-865-134-457; 088-024-489-402-290; 091-891-734-697-576; 092-187-604-878-931; 092-274-926-085-614; 093-630-176-152-615; 100-176-205-783-374; 100-708-135-403-667; 101-865-633-170-566; 103-460-999-207-914; 103-766-859-722-30X; 104-102-419-773-300; 105-540-376-402-900; 107-773-427-002-721; 108-380-623-475-197; 110-739-630-783-032; 111-224-910-266-746; 111-521-799-837-950; 114-566-854-744-078; 116-223-747-571-448; 117-031-137-221-23X; 125-497-482-986-289; 131-114-697-432-263; 132-564-242-135-777; 133-135-572-308-715; 133-203-717-902-873; 134-429-262-903-287; 134-903-178-811-246; 136-807-218-091-806; 145-990-548-098-466; 148-645-733-462-057; 150-646-319-619-692; 150-783-459-512-580; 157-050-461-236-34X; 163-064-022-279-043; 166-016-257-634-612; 174-950-733-884-317; 176-735-388-619-352; 187-636-969-899-335,0,false,, -167-063-739-337-627,Research on sustainable tourism and biodiversity: a bibliometric analysis,2024-01-02,2024,journal article,Anatolia,13032917; 21566909,Informa UK Limited,United Kingdom,Podili Harish; Y. Venkata Rao,"This study intends to analyse sustainable tourism and biodiversity research from a longitudinal point of view from 1995 to 2022. Collected 290 research articles published in the Scopus database and applied rigorous inclusion and exclusion criteria to select them for bibliometric analysis. Bibliometrix and VOSviewer tools were employed to analyse and depict the research. Co-citation of cited references, co-citation on a timeline basis, and bibliometric coupling analysis are performed to examine the trends and patterns. Further, inferred a thematic structure of sustainable tourism and biodiversity, uncovering seven co-citation clusters, twenty co-citation clusters on a timeline basis, and eleven bibliometric coupling clusters. This study offers various perspectives on sustainable tourism and biodiversity research for theoretical and practical advancements.",35,4,702,722,Timeline; Bibliographic coupling; Scopus; Tourism; Citation; Biodiversity; Geography; Bibliometrics; Thematic map; Citation analysis; Regional science; Data science; Environmental resource management; Computer science; Library science; Political science; Environmental science; Ecology; Cartography; Biology; Archaeology; MEDLINE; Law,,,,,,http://dx.doi.org/10.1080/13032917.2023.2300120,,10.1080/13032917.2023.2300120,,,0,000-848-264-004-813; 000-930-868-404-394; 002-052-422-936-00X; 002-172-807-698-037; 002-922-749-260-394; 008-991-776-721-333; 009-022-977-275-257; 009-219-536-257-925; 012-475-076-957-525; 013-507-404-965-47X; 013-667-374-979-75X; 013-764-699-082-283; 014-358-697-719-829; 014-361-778-120-583; 015-122-707-832-776; 015-485-770-426-896; 018-381-206-820-852; 019-746-655-861-196; 023-927-221-065-800; 025-410-058-914-155; 025-660-944-681-108; 027-434-527-905-948; 031-488-311-629-436; 032-318-770-533-876; 033-643-820-934-332; 035-275-486-007-109; 037-565-570-256-894; 038-735-788-688-96X; 039-889-887-291-069; 040-132-697-304-982; 042-200-814-432-591; 042-360-499-313-287; 042-889-006-999-63X; 042-952-708-120-596; 043-490-266-662-680; 046-059-775-592-394; 046-992-864-415-70X; 054-248-129-895-369; 056-656-890-057-969; 056-746-796-599-584; 058-107-361-602-096; 059-308-188-826-850; 063-867-989-846-259; 064-859-860-643-983; 065-010-405-236-060; 066-849-661-222-258; 067-869-896-533-418; 074-547-294-576-420; 074-831-830-747-376; 075-130-341-868-331; 077-918-560-780-184; 083-087-993-459-006; 086-288-209-916-008; 086-940-278-594-027; 087-018-812-578-003; 087-228-930-252-544; 088-786-421-434-115; 090-171-018-969-09X; 090-385-768-259-998; 091-003-598-516-436; 093-533-502-370-024; 093-629-951-580-365; 094-176-696-294-675; 096-362-153-413-49X; 102-018-233-291-667; 102-732-838-251-180; 104-633-933-903-457; 112-577-217-017-493; 113-554-258-200-133; 113-595-234-065-038; 119-440-486-765-008; 120-257-915-252-826; 125-701-245-305-932; 125-724-135-450-508; 126-776-031-845-039; 127-580-512-767-74X; 135-114-552-887-481; 141-211-062-747-314; 143-947-079-570-716; 173-504-571-067-261; 187-703-070-908-528; 187-893-722-328-423; 192-595-241-804-228; 196-780-178-356-652; 198-179-615-845-442,5,false,, -167-265-509-563-835,Research Trend of User-Generated Content in Tourism,2024-07-04,2024,journal article,Dinasti International Journal of Education Management And Social Science,26866331; 26866358,Yayasan Dharma Indonesia Tercinta (Dinasti),,Batara Nobon Siregar; Ari Sulistyanto; Hamida Syari Harahap; Wichitra Yasya; Dwinarko Dwinarko,"The habit of sharing travel experiences on social media is increasingly attached to modern life today, making the theme of User Generated Content (UGC) in tourism never be uninteresting topic to research. Research on UGC in tourism grew 30.31% over the last 10 years. This study uses a bibliometric approach to analyze the database from Scopus with the keyword ""User Generated Content"" AND Tourism, in the period 2014 – 2023. 504 documents were found from the database and use PRISMA to select, narrowing it down to 321 documents that were used as units of analysis. The application ""Biblioshiny R package Bibliometrix"" is used for data analysis and visualization. The results showed that the theme with “online”, “findings” and “reviews”, is still a research trend in the future.",5,5,1362,1373,User-generated content; Content (measure theory); Tourism; Computer science; Geography; Regional science; Information retrieval; Business; World Wide Web; Mathematics; Social media; Mathematical analysis; Archaeology,,,,,,http://dx.doi.org/10.38035/dijemss.v5i5.2797,,10.38035/dijemss.v5i5.2797,,,0,,0,true,,bronze -167-724-558-185-033,Knowledge mapping of exosomes in prostate cancer from 2003 to 2022: a bibliometric analysis.,2024-07-24,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Yingjie Li; Lin Ma; Hualin Chen; Zhaoheng Jin; Wenjie Yang; Yi Qiao; Zhigang Ji; Guanghua Liu,"Prostate cancer (PCa) is highly prevalent among males worldwide. The investigation of exosomes in PCa has emerged as a dynamic and important research area. To visually depict the prominent research areas and evolutionary patterns of exosomes in PCa, we performed a comprehensive analysis via bibliometric methods.; Studies were retrieved from the Web of Science Core Collection. CiteSpace, VOSviewers, and the R package ""bibliometrix"" were employed to analyze the relationships and collaborations among countries/regions, organizations, authors, journals, references, and keywords.; Over the past 20 years (2003-2022), 995 literatures on exosomes in PCa have been collected. The findings indicate a consistent upward trend in annual publications with the United States being the leading contributor. Cancers is widely recognized as the most prominent journal in this area. In total, 5936 authors have contributed to these publications, with Alicia Llorente being the most prolific. The primary keywords associated with research hotspots include ""liquid biopsy"", ""identification"", ""growth"", ""microRNAs"", and ""tumor-derived exosomes"".; Our analysis reveals that investigating the intrinsic mechanisms of exosomes in PCa pathogenesis and exploring the potential of exosomes as biomarkers of PCa constitute the principal focal points in this domain of research.; © 2024. The Author(s).",15,1,307,,Microvesicles; Prostate cancer; Principal component analysis; microRNA; Bibliometrics; Cancer; Computational biology; Biology; Medicine; Library science; Internal medicine; Computer science; Gene; Biochemistry; Artificial intelligence,Bibliometrics; CiteSpace; Exosomes; Prostate cancer; VOSviewer,,,National High Level Hospital Clinical Research Funding (2022-PUMCH-C-034),https://link.springer.com/content/pdf/10.1007/s12672-024-01183-x.pdf https://doi.org/10.1007/s12672-024-01183-x,http://dx.doi.org/10.1007/s12672-024-01183-x,39048891,10.1007/s12672-024-01183-x,,PMC11269540,0,000-584-664-954-74X; 001-976-614-734-609; 002-052-422-936-00X; 002-379-023-923-943; 002-448-715-464-131; 003-185-385-469-670; 003-870-745-672-716; 004-184-611-116-710; 004-686-546-736-816; 006-580-440-816-209; 007-500-155-247-91X; 008-082-689-209-35X; 011-301-822-302-672; 012-660-470-515-308; 013-507-404-965-47X; 014-783-001-818-923; 015-453-955-064-354; 017-805-498-249-773; 021-518-513-932-793; 022-968-183-623-684; 024-752-140-140-842; 029-539-034-036-821; 039-310-817-767-046; 040-873-207-614-119; 046-132-221-218-868; 047-567-163-169-541; 047-596-783-472-86X; 048-238-386-824-995; 049-867-608-561-237; 052-179-133-160-622; 053-696-798-568-851; 063-483-230-428-112; 063-626-189-758-077; 065-080-761-006-564; 072-832-318-513-724; 079-231-495-225-513; 080-977-108-232-315; 081-312-966-056-426; 085-582-026-104-462; 090-369-106-530-611; 090-476-872-676-699; 097-763-795-228-02X; 104-635-869-071-885; 105-440-199-577-815; 106-971-366-659-041; 108-069-516-974-845; 111-635-851-645-688; 116-684-909-517-631; 128-629-290-036-298; 130-909-922-018-660; 131-773-931-774-122; 143-475-316-503-654; 145-768-898-521-431; 162-905-385-190-555; 163-967-723-902-253; 175-858-104-109-910; 191-861-722-739-060,1,true,cc-by,gold -167-731-755-874-597,Evolution of Ethics and Entrepreneurship: Hybrid Literature Review and Theoretical Propositions,2024-09-11,2024,journal article,Journal of Business Ethics,01674544; 15730697,Springer Science and Business Media LLC,Netherlands,Sebastián Uriarte; Cristian Geldes; Jesús Santorcuato,"Entrepreneurship has been highlighted as one of the major forces in addressing significant economic, social, and environmental challenges. These challenges have raised new ethical questions, leading to an explosive growth of research at the intersection of ethics and entrepreneurship. This study provides an overview of the evolution of the scientific literature on the interplay between ethics and entrepreneurship to propose a research proposition with standardized protocols and a broad time limit. Specifically, in a hybrid literature review, 516 articles from peer-reviewed journals indexed in Scopus were analyzed. The review revealed that the field mainly comprises six themes. Through the analysis of each theme, gaps are identified and structured and used to build theoretical proposals for future research agendas applied to current societal challenges. Understanding the link between entrepreneurship and ethics guides practices improves decisions, addresses challenges, promotes sustainability, enhances academia, and builds trust, fostering a responsible, beneficial entrepreneurial environment for society and the economy.",198,2,321,343,Business ethics; Quality of Life Research; Entrepreneurship; Sociology; Engineering ethics; Epistemology; Political science; Philosophy; Public relations; Law; Engineering; Medicine; Nursing; Public health,,,,,,http://dx.doi.org/10.1007/s10551-024-05815-8,,10.1007/s10551-024-05815-8,,,0,000-290-983-065-508; 000-986-450-259-591; 001-818-411-563-383; 002-007-743-792-673; 003-337-198-578-820; 003-771-659-285-88X; 004-228-828-590-79X; 008-033-055-527-734; 009-292-486-329-564; 009-795-599-823-213; 010-410-989-837-528; 010-694-289-280-332; 012-061-800-080-251; 012-313-867-051-955; 013-004-686-217-482; 013-422-282-868-950; 013-524-854-219-241; 014-255-957-838-057; 014-256-799-250-518; 015-235-670-146-895; 015-692-170-714-052; 016-361-340-630-581; 017-563-281-589-567; 017-664-472-557-173; 018-244-982-737-516; 018-567-201-472-401; 020-541-182-097-541; 022-807-616-055-954; 023-085-009-422-518; 023-926-428-849-341; 024-077-991-709-332; 025-575-346-673-478; 025-901-392-108-681; 027-000-682-523-044; 027-629-895-089-411; 028-209-026-033-913; 028-638-299-770-885; 029-456-028-515-662; 030-388-951-504-67X; 031-712-374-809-788; 034-068-993-878-744; 037-892-519-894-266; 038-553-136-084-565; 038-650-957-921-679; 039-164-142-658-497; 040-994-715-977-208; 042-754-839-422-204; 045-118-156-568-396; 046-992-864-415-70X; 048-064-030-371-326; 048-356-557-500-141; 049-822-477-710-01X; 051-647-739-244-271; 052-900-776-124-087; 054-356-213-596-124; 054-892-602-015-388; 055-823-152-844-193; 057-950-697-210-005; 058-754-771-883-418; 060-370-964-747-649; 060-884-078-634-98X; 064-850-730-396-303; 066-222-700-665-74X; 069-615-672-980-131; 072-856-861-900-730; 074-316-920-219-108; 075-636-596-178-023; 078-801-402-124-429; 079-486-325-974-882; 079-821-815-152-748; 080-713-429-981-481; 082-813-256-469-295; 085-752-735-414-008; 088-210-323-344-747; 089-473-170-566-883; 095-059-003-999-802; 098-994-150-576-208; 101-544-302-986-58X; 101-747-986-171-911; 102-056-343-199-076; 106-661-862-917-878; 108-480-657-785-191; 111-194-455-268-007; 111-792-162-428-118; 113-682-442-621-962; 117-709-213-459-773; 119-749-987-297-332; 120-785-684-616-096; 123-461-426-311-124; 123-605-471-504-590; 125-312-698-109-417; 125-418-653-862-603; 128-082-509-450-439; 134-609-481-665-790; 136-976-716-535-374; 139-944-783-625-700; 140-278-261-428-770; 141-026-656-461-626; 141-519-229-972-259; 144-035-968-812-935; 145-419-965-152-846; 152-997-535-579-725; 153-274-656-993-962; 171-524-394-101-654; 174-590-021-413-414; 174-790-569-333-440; 176-452-161-345-334; 183-975-680-050-470; 188-804-758-678-555; 197-514-587-607-349,4,true,cc-by-nc-nd,hybrid -167-984-878-085-585,"Research progress of wearable devices in textile field: a bibliometric analysis using VOSviewer, RStudio bibliometrix and CiteSpace software tools",2024-11-06,2024,journal article,International Journal of Clothing Science and Technology,09556222; 17585953,Emerald,United Kingdom,Tianqi Xu; Min Wang,"PurposeThe purpose of this paper is to analyze research trends on “Wearable devices in textile filed” from 2010 to 2023 and determine the important keywords, nations and journals associated with this topic.Design/methodology/approachUtilizing journal literature on wearable devices from the 2010 to 2023 Web of Science (WoS) database, this study employs VOSviewer, biblioshiny of the R software package and the specialized software CiteSpace to generate knowledge graphs for measuring retrieval outcomes.FindingsThe research on wearable devices integrated into textiles between 2010 and 2023 can be divided into three stages: initial slow progress, subsequent rapid advancement and final slow progress, indicating a general rise in the quantity of published material. The terms “fabrication,” “wearable electronics” and “design” are closely linked in this field. China is the most globally networked country in this field, according to the World Collaboration Map. NANO ENERGY ranked first in the number of articles published in journals, with 18 articles and 1,151 citations.Originality/valueThe study identified the present state and research trends in the field of “Wearable devices in textile filed,” offering valuable information for researchers to enhance their understanding of the field’s progress.",37,1,166,179,Wearable computer; Originality; Wearable technology; Field (mathematics); Textile; Computer science; Software; Engineering; Clothing; Data science; Geography; Psychology; Mathematics; Archaeology; Pure mathematics; Embedded system; Social psychology; Creativity; Programming language,,,,,,http://dx.doi.org/10.1108/ijcst-05-2024-0116,,10.1108/ijcst-05-2024-0116,,,0,002-052-422-936-00X; 009-081-178-916-097; 010-722-846-883-191; 013-507-404-965-47X; 016-367-422-347-509; 017-176-064-915-055; 017-430-100-229-097; 019-128-299-119-244; 022-068-312-435-53X; 027-062-916-549-612; 046-992-864-415-70X; 055-625-254-883-356; 059-145-282-334-066; 064-400-499-357-900; 065-819-072-267-251; 069-593-061-782-22X; 074-689-637-760-304; 080-977-108-232-315; 085-435-266-416-887; 091-891-734-697-576; 106-903-166-839-393; 109-229-402-681-936; 114-965-683-303-275; 120-978-399-456-59X; 143-375-029-163-994; 148-827-030-688-356; 164-848-685-839-285,1,false,, -168-014-160-303-845,Bibliometric analysis of scientific publications on tax evasion using bibliometrix R and the VOSviewer tool,,2022,journal article,European Scientific e-Journal,26950243,Tuculart s.r.o.,,Elena Hlaciuc; Florina Creţu,"Tax evasion is an illegal activity that consists in not paying taxpayers' obligations to the state, through fraudulent maneuvers that change the amount of taxes to be paid.This research analyzes the scientific production with reference to the phenomenon of tax evasion in the Scopus database during the years 2010-2022.This research aims to determine the state of knowledge of the phenomenon of tax evasion at the global level, identify future research trends, the most frequently cited authors in the field, the collaboration between research institutions, the co-author network of countries, as well as the most addressed publications from different studies, journals and countries that address the topic of tax evasion.Publications with reference to the phenomenon of tax evasion were retrieved and extracted from Scopus, which is a bibliographic and bibliometric database in online format, including scientific journals, delivered via the Internet.Provides access to abstracts of scientific articles from more than 22,400 international scientific journals published by more than 5,000 international publishing houses, without language restrictions, in the reference period 2010-2022.Bibliometrix R was used in calculating and visualizing bibliographic information extraction and performing descriptive analysis.The VOSviewer tool was used to construct, review and visualize the geographical areas with the most frequent studies on this topic, by analyzing the international collaboration of the authors.",,,,,Tax evasion; Evasion (ethics); Data science; Computer science; Economics; Public economics; Biology; Genetics; Immune system,,,,,https://zenodo.org/records/7458621/files/ecn2022-10-01.pdf https://zenodo.org/record/7458621,http://dx.doi.org/10.47451/ecn2022-10-01,,10.47451/ecn2022-10-01,,,0,,0,true,,gold -168-164-287-409-982,Nursing Informatics Research: A Bibliometric Analysis from 1989 to 2023.,2024-07-24,2024,journal article,Studies in health technology and informatics,18798365; 09269630,IOS Press,Netherlands,Chun-Wei Liu; Zu-Chun Lin; Malcolm Koo,"Nursing informatics has evolved rapidly since its inception. Despite its growth, there remains a gap in comprehensive bibliometric analyses of the field's development and themes. The study aimed to provide an overview of the evolution and current status of nursing informatics by conducting a bibliometric analysis of the literature from 1989 to 2023. Utilizing the Science Citation Index Expanded edition of the Web of Science Core Collection, 483 original English-language articles were analyzed using Bibliometrix 4.1. The results revealed a steady increase in publications, with the United States as the leading contributor. Thematic analysis indicates a shift from basic informatics integration to advanced technologies like artificial intelligence, reflecting the dynamic nature and expanding scope of nursing informatics. These findings highlight the need for ongoing research, enhanced digital literacy, and interdisciplinary collaboration, emphasizing the field's critical role in advancing healthcare in the digital age.",315,,170,,Informatics; Health informatics; Scope (computer science); Thematic analysis; Health Administration Informatics; Social Sciences Citation Index; Field (mathematics); Engineering informatics; Data science; Citation; Computer science; Library science; Engineering ethics; Health care; Science Citation Index; Political science; Sociology; Qualitative research; Engineering; Social science; Law; Mathematics; Pure mathematics; Programming language,Nursing informatics; Web of Science; bibliometrics; research trends,Bibliometrics; Nursing Informatics; Nursing Research; Artificial Intelligence,,,https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI240128 https://doi.org/10.3233/shti240128,http://dx.doi.org/10.3233/shti240128,39049247,10.3233/shti240128,,,0,,0,true,cc-by-nc,hybrid -168-220-976-283-418,Corporate Social Responsibility actions and the economic sustainability of Small and Medium Sized Enterprises: a systematic literature review,2025-05-01,2025,journal article,Tec Empresarial,16593359; 16592395,Instituto Tecnologico de Costa Rica,,Tania Mora Ortega; Dyalá De la O Cordero; Antonio Juan Briones Peñalver,"The purpose of this research is to identify the scientific activity dealing with corporate social responsibility (CSR) actions and the economic sustainability of Small and Medium sized Enterprises (SMEs) during 2000-2023. We analyze the evolution of conceptual, intellectual, and social aspects through a systematic literature review using the PRISMA methodology. Data analysis was carried out using the tools Bibliometrix and Biblioshiny on a sample of 62 academic articles indexed in the Web of Science (WoS) database. Results indicate that the scientific activity in this field has grown significantly, being 2023 the year with the highest number of publications, while researchers have been classified into five areas:1-Corporate Social Responsibility, 2-Strategy, 3-Perceptions, 4-Leadership, and 5-Financial performance. Other subject areas continue to be of great interest for research, such as ""causal and performance indicators"", ""disclosure, management and sustainability"", ""context and CSR"", and ""perspectives models and determinants""",19,2,90,111,Sustainability; Corporate social responsibility; Business; Systematic review; Social responsibility; Accounting; Public relations; Political science; MEDLINE; Ecology; Law; Biology,,,,,,http://dx.doi.org/10.18845/te.v19i2.7966,,10.18845/te.v19i2.7966,,,0,,0,true,cc-by-nc-nd,gold -168-332-903-027-188,Análisis bibliométrico sobre la producción científica del trabajo social digital con Scopus y bibliometrix,2021-10-04,2021,,,,,,Darwin Alexis Cruz García; Diana Carolina Tibana Rios,"Realizar un acercamiento sobre la produccion bibliografica del trabajo social digital o e-social work a nivel mundial, permitio como se vera en este articulo, construir un marco de referencia sobre la cantidad y evolucion de los contenidos globales que se han realizado del tema desde un nivel cientifico. Este estudio bibliometrico retrospectivo y descriptivo de tipo documental se realizo a partir de la revision de los datos de documentos originales depositados en la base de datos Scopus y exportados a la herramienta bibliometrix version 2.2. Como hallazgos se encuentran la evolucion historica por anos, prevalencia de autores y afiliacion institucional de los mismos, concentracion por ciudad y las palabras claves. Todo lo anterior basado en los recursos de la matematica y estadistica como ejes centrales de la bibliometria",6,1,82,102,,,,,,https://biblat.unam.mx/pt/revista/sinergias-educativas/articulo/analisis-bibliometrico-sobre-la-produccion-cientifica-del-trabajo-social-digital-con-scopus-y-bibliometrix,https://biblat.unam.mx/pt/revista/sinergias-educativas/articulo/analisis-bibliometrico-sobre-la-produccion-cientifica-del-trabajo-social-digital-con-scopus-y-bibliometrix,,,3204106221,,0,,0,false,, -168-352-727-426-494,BIBLIOMETRIC ANALYSIS ON INTERNAL CORPORATE GOVERNANCE: WHAT IS THE NEXT RESEARCH?,,2022,journal article,Research In Management and Accounting,27233804,Universitas Katolik Widya Mandala Surabaya,,Ilham Maulana,"This study aims to internal corporate governance literature with a bibliometric analysis approach. To carry out this analysis, the data obtained from Dimensions with certain criteria are used, then mapping and analysis are carried out using VOSviewer and Bibliometrix. From the results of this analysis, researchers found the conceptual structure and intellectual structure used in the internal corporate governance literature. Then this research also found journals, authors, organizations, and countries that have the most significant contribution in the development of internal corporate governance. From the analysis that has been done, the researcher found that there are still topics of corporate control that researchers around the world rarely touch. This paper provides an overview of how the literature on internal corporate governance and provides an opportunity for further researchers to develop research on internal corporate governance",5,2,55,67,Corporate governance; Business; Accounting; Stakeholder; Control (management); Knowledge management; Political science; Public relations; Computer science; Management; Economics; Finance,,,,,http://journal.wima.ac.id/index.php/RIMA/article/download/3998/3146 https://doi.org/10.33508/rima.v5i2.3998,http://dx.doi.org/10.33508/rima.v5i2.3998,,10.33508/rima.v5i2.3998,,,0,,3,true,cc-by-sa,gold -168-379-073-154-361,Research streams and open challenges in the metaverse,2023-07-19,2023,journal article,The Journal of Supercomputing,09208542; 15730484,Springer Science and Business Media LLC,Netherlands,Carmen Carrión,,80,2,1598,1639,Metaverse; Computer science; Data science; Merge (version control); Virtual reality; Architecture; Human–computer interaction; Information retrieval; Art; Visual arts,,,,"Ministerio de Ciencia, Innovación y Universidades; European Regional Development Fun",,http://dx.doi.org/10.1007/s11227-023-05544-1,,10.1007/s11227-023-05544-1,,,0,000-827-187-646-317; 002-052-422-936-00X; 003-081-869-604-094; 003-377-457-305-680; 004-085-738-535-206; 005-008-035-458-133; 009-426-971-455-901; 012-794-932-423-277; 013-507-404-965-47X; 013-524-854-219-241; 014-129-634-820-525; 017-311-128-771-206; 017-839-472-387-92X; 019-819-261-965-237; 020-936-040-286-394; 023-205-044-304-81X; 024-769-334-245-598; 024-885-803-632-442; 031-378-521-348-344; 031-531-051-422-754; 032-870-782-800-547; 035-757-732-617-263; 037-453-781-297-614; 039-798-634-249-117; 040-623-948-800-718; 042-472-641-466-169; 043-973-536-005-16X; 046-096-656-702-960; 047-908-492-267-057; 052-496-370-540-441; 053-178-657-581-77X; 057-988-439-759-090; 058-775-933-633-837; 058-998-027-851-38X; 061-286-166-314-990; 064-400-499-357-900; 064-630-309-612-688; 070-834-694-189-784; 077-220-267-493-915; 079-200-950-688-973; 081-554-059-876-297; 086-044-580-403-791; 089-322-692-926-665; 096-110-581-977-776; 096-434-009-047-130; 098-082-532-899-182; 099-656-854-792-632; 110-541-875-849-411; 112-524-198-294-495; 116-701-990-558-335; 117-606-130-632-188; 120-353-842-716-385; 120-586-553-592-272; 122-682-468-170-924; 126-657-724-275-428; 130-829-338-991-226; 132-081-757-526-375; 132-875-825-409-897; 133-900-773-718-898; 134-382-126-797-664; 137-174-765-225-702; 138-420-434-223-451; 143-740-861-296-405; 146-801-156-136-815; 155-894-492-886-991; 157-569-024-890-678; 162-650-013-833-212; 177-778-631-705-151; 182-512-406-477-167; 184-849-770-478-939; 185-050-459-076-354; 188-798-445-030-83X; 189-085-909-408-113; 193-944-704-251-316; 199-640-705-271-621,18,false,, -168-654-073-187-546,Trends and frontiers in coal mine groundwater research: insights from bibliometric analysis,2023-09-26,2023,journal article,Geomechanics and Geophysics for Geo-Energy and Geo-Resources,23638419; 23638427,Springer Science and Business Media LLC,,Yang Xiang; Suping Peng; Wenfeng Du,"AbstractGlobally, studying the impact of coal mining on groundwater remains challenging. This is because the exploitation of coal resources and the sustainable development of groundwater resources involve economic, social, and environmental aspects. Over the last few decades, the number of publications on groundwater-related studies in coal mining areas has increased. However, they are not currently reviewed in a widely visible manner through bibliometric analyses. This study investigated groundwater research in coal mining areas worldwide using scientometric analysis based on 1196 articles from the Web of Science database to provide a global perspective and gain quantitative insight into research frontiers and trends in the field by mapping existing knowledge. We analyzed the key contributors and development processes of coal mine groundwater research and identified four research frontiers based on scientometric mapping results with an understanding of the research field: numerical modeling, conceptual modeling and mechanisms, feedback mechanisms between anthropogenic-environmental systems and groundwater systems, ground subsidence management, groundwater quality evaluation and risk assessment, and groundwater resource management in coal mines. Finally, we summarize the current challenges and propose methods to promote the green mining of coal resources and the sustainable development and management of groundwater resources.",9,1,,,Groundwater; Coal mining; Groundwater resources; Resource (disambiguation); Sustainable development; Environmental science; Coal; Environmental planning; Environmental resource management; Aquifer; Geography; Computer science; Geology; Ecology; Biology; Computer network; Geotechnical engineering; Archaeology,,,,Intelligent and Safe Mining for Coal Resources; 111 project,https://link.springer.com/content/pdf/10.1007/s40948-023-00663-8.pdf https://doi.org/10.1007/s40948-023-00663-8,http://dx.doi.org/10.1007/s40948-023-00663-8,,10.1007/s40948-023-00663-8,,,0,000-470-358-038-270; 001-481-507-992-368; 001-986-744-355-323; 002-227-435-183-600; 002-263-487-488-316; 002-355-195-984-535; 003-184-814-486-029; 003-998-547-620-045; 005-018-610-434-234; 005-508-177-991-225; 006-189-445-536-642; 007-894-858-463-429; 008-455-533-858-58X; 010-099-078-337-646; 010-175-443-095-676; 011-637-853-954-701; 013-366-197-996-743; 014-963-945-518-133; 016-479-205-676-37X; 016-735-934-883-352; 017-300-790-093-995; 017-861-580-056-651; 022-668-259-136-15X; 024-630-592-046-181; 025-885-511-016-820; 026-988-474-302-921; 027-082-702-945-255; 028-119-119-062-984; 030-353-234-413-273; 033-515-942-650-817; 033-595-732-256-427; 034-378-762-012-277; 034-772-299-258-587; 037-202-405-043-569; 041-948-932-770-309; 042-786-342-422-299; 045-430-024-804-998; 045-776-781-332-391; 048-842-986-055-027; 051-435-532-718-690; 051-489-828-959-390; 056-687-445-824-80X; 060-806-916-868-758; 063-084-329-517-918; 064-250-924-579-758; 065-631-619-471-201; 069-984-773-494-363; 070-065-352-082-609; 073-191-421-821-097; 074-013-962-928-035; 082-561-699-318-500; 082-603-930-040-20X; 082-828-680-389-384; 084-158-689-955-437; 092-203-554-311-335; 097-308-932-594-735; 099-725-638-381-392; 100-588-462-362-15X; 101-825-643-664-643; 103-564-054-366-533; 104-108-644-806-33X; 104-728-067-284-208; 106-804-379-968-734; 108-241-674-897-218; 108-337-453-511-074; 110-260-405-386-247; 116-278-581-996-996; 118-769-608-730-346; 118-992-994-360-348; 121-983-441-714-701; 124-238-006-695-592; 128-095-804-660-837; 128-439-753-239-431; 131-562-852-523-683; 132-771-021-355-807; 135-992-483-710-074; 140-188-407-149-979; 140-485-487-446-164; 143-901-190-734-148; 151-510-271-797-716; 157-055-661-382-723; 159-076-605-797-110; 164-220-890-227-356; 168-075-270-223-693; 178-754-188-322-729; 188-890-802-916-076,4,true,cc-by,gold -168-691-198-952-750,Bibliometric Review of Biodiversity Offsetting During 1992–2019,2022-01-06,2022,journal article,Chinese Geographical Science,10020063; 1993064x,Springer Science and Business Media LLC,China,Shuling Yu; Baoshan Cui; Chengjie Xie; Ying Man; Jing Fu,"Biodiversity offsetting plays a crucial role in managing the impacts of development on natural habitats. Developers, conservation groups, governments and financial institutions have used biodiversity offsetting to design measurable conservation actions to compensate for significant residual adverse biodiversity impacts arising from development. However, the concepts and methodologies of biodiversity offsetting have rarely been systematically reviewed, and best practices are still lacking. This hinders the development and applications of this field, and makes it difficult for new researchers to learn, develop, and apply biodiversity offsetting. This paper aims to review research progress on biodiversity offsetting during the period of 1992 to 2019. We mainly used bibliometric analysis and social network analysis methods to expose the topic diversity, development and promotion of this research field, and assess collaboration among biodiversity offsetting scholars. Our research identified 1190 records, and revealed that the total number of publications increased rapidly since 2002. The most productive journal, country, and author were Biological Conservation, USA, and Dr. Maron M of University of Queensland, respectively. Co-author analysis identified that the 23 authors most relevant to biodiversity offsetting were involved in a collaboration network. And they were mainly from 30 countries in a collaboration network, and the authors from USA, Australia and the United Kingdom have the most cooperation, which mainly driven by policy related to biodiversity offsetting. Our review shows that biodiversity offsetting research is at an early stage of rapid development with topically diverse and collaborative science domains. The majority of studies focus on terrestrial environments, which makes the implementation of aquatic ecosystem is more difficult. Theoretical problems and the implications of research evolution and social network in biodiversity offsetting are discussed, and further development of the theory and methodologies of biodiversity offsetting and management was recommend.",32,2,189,203,Biodiversity; Promotion (chess); Environmental planning; Environmental resource management; Measurement of biodiversity; Business; Geography; Biodiversity conservation; Natural resource economics; Political science; Ecology; Economics; Biology; Politics; Law,,,,,,http://dx.doi.org/10.1007/s11769-022-1265-5,,10.1007/s11769-022-1265-5,,,0,000-660-068-027-351; 002-026-966-561-50X; 002-965-272-635-688; 003-414-352-003-037; 004-343-857-634-863; 006-348-158-828-525; 006-849-016-033-001; 011-618-463-748-968; 012-565-861-978-523; 013-507-404-965-47X; 013-526-191-378-071; 014-914-494-769-361; 015-306-917-663-970; 016-936-118-904-486; 018-706-760-301-42X; 019-181-477-415-517; 019-269-049-923-538; 019-948-247-949-637; 020-617-663-796-632; 021-052-485-538-278; 021-715-539-106-740; 023-343-995-715-265; 024-770-059-472-443; 026-732-144-957-600; 027-222-531-228-164; 028-609-711-997-860; 030-475-937-195-642; 030-549-578-899-179; 032-317-949-579-095; 032-340-865-708-078; 035-889-628-009-043; 035-899-559-570-476; 036-653-392-342-32X; 038-352-989-429-851; 039-863-416-507-104; 041-566-024-953-739; 044-394-838-712-601; 047-523-773-621-326; 048-227-484-788-98X; 053-126-561-089-540; 057-153-002-929-266; 058-473-310-769-590; 061-680-490-238-008; 061-849-474-229-911; 063-663-054-349-80X; 065-370-194-805-030; 065-685-431-494-085; 068-257-256-174-364; 068-599-880-420-987; 072-441-193-508-498; 072-779-629-825-549; 072-898-315-039-504; 073-893-722-886-800; 080-183-186-405-926; 081-909-762-807-488; 085-894-805-285-285; 085-997-606-614-092; 086-355-415-218-267; 093-355-302-681-101; 094-416-358-016-605; 101-752-490-869-458; 110-873-024-686-352; 112-900-528-654-120; 113-674-113-505-741; 115-521-323-367-135; 138-865-125-646-241; 141-200-607-894-303; 147-004-911-186-029; 147-411-208-380-08X; 149-118-245-497-367; 150-158-574-138-607; 155-960-191-898-81X; 157-569-024-890-678; 159-306-125-917-84X; 168-694-765-678-22X; 171-406-709-215-748,6,true,,hybrid -168-695-440-639-569,Main areas of research and scientific production regionalized by Policosanol biorefining route: from the 1990s to the 2020s,2023-07-12,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Rilton Gonçalo Bonfim Primo; Ricardo de Araújo Kalid; Manuel Díaz de los Ríos; Jesus Martín-Gil; Pablo Martín Ramos,"This Table 1 presents the results of surveys, in 18 Ibero-American countries and in the world, carried out in the Science Citation Index Expanded (SCI-E) or Web of Science - Core Collection - Clarivate Analytics – (WoS) and Scopus (Elsevier): AR - Argentina, BR - Brazil, CL - Chile, CO - Colombia, CR - Cota Rica, CU - Cuba, DO - Dominican Republic, EC - Ecuador, ES - Spain, GT - Guatemala, HN - Honduras, MX - Mexico, NI - Nicaragua, PA - Panama, PE - Peru, PT - Portugal, SV - El Salvador, UY - Uruguay. Data from the two databases were merged using the Bibliometrix of R program (Version 4.1.1), as well as the Biblioshiny, for scientometrics and bibliometrics. Merging the Scopus and Web of Science bases, the scientometric methodology of K-Synth (Bibliometrix) is applied here, according to which the scientific production of each country is measured by the number of appearances of authors by country affiliations. Thus, if in an article there are, for example, three authors working, respectively, in Brazil, Spain and the USA, the appearance counter will be increased by 1 for each of them. Due to the identification of some gaps, the electronically merged data were reconciled with the original databases.",,,,,Biorefining; Production (economics); Business; Computer science; Engineering; Economics; Waste management; Microeconomics; Biofuel; Biorefinery,,,,,https://zenodo.org/record/8140867,http://dx.doi.org/10.5281/zenodo.8140867,,10.5281/zenodo.8140867,,,0,,0,false,, -169-091-179-632-580,Dissemination of Social Accounting Information: A Bibliometric Review,2021-03-19,2021,journal article,Economies,22277099,MDPI AG,,Margarida Rodrigues; Maria do Céu Gaspar Alves; Cidália Oliveira; Vera Teixeira Vale; José Vale; Rui Silva,"The discussion in recent decades about sustainable development issues has given rise to a new accounting dimension: social accounting. Currently, this issue remains an emerging theme. Although there are some studies and literature reviews, none include disclosure of social accounting information or the analysis of research paradigms. This article reviews the research on social accounting disclosure and tries to answer the following research questions: What research streams have been followed? Which theories and research paradigms have been used? The search for articles to be included in the literature review was performed through the Web of Science. The 126 articles obtained were later analyzed using Bibliometrix software. Results expose the growing interest in this theme and identify three distinct research lines (three clusters): Cluster 1—Social accounting disclosures, Cluster 2—Legitimacy vs. disclosure of social accounting, and Cluster 3—Motivations for disclosure of social accounting. The main contribute of this article resides, on the one hand, in the fact that no literature review articles have been found that include the theme of the disclosure of information on social accounting and, on the other hand, the treatment of data has been done with innovative software, an R package for bibliometric and co-citation analysis called Bibliometrix. As well as mapping the literature, another theoretical contribution of this study was identifying the main research approaches used in the studies. Within the paradigmatic plurality of social accounting research, the results suggest that social accounting research can also be critically addressed when addressing the sustainability challenges posed by climate change or carbon emissions, among many other aspects. This study is, to our knowledge, the first bibliometric review done about social accounting information disclosure.",9,1,41,,Sociology; Social accounting; Theme (narrative); Dimension (data warehouse); Voluntary disclosure; R package; Research questions; Public relations; Sustainable development; Sustainability,,,,Fundação para a Ciência e a Tecnologia,https://repositorium.sdum.uminho.pt/bitstream/1822/72447/1/economies-09-00041.pdf https://www.mdpi.com/2227-7099/9/1/41/pdf https://ideas.repec.org/a/gam/jecomi/v9y2021i1p41-d520551.html http://repositorium.sdum.uminho.pt/handle/1822/72447 https://www.mdpi.com/2227-7099/9/1/41,http://dx.doi.org/10.3390/economies9010041,,10.3390/economies9010041,3137622433,,0,002-800-351-395-955; 002-900-783-342-943; 004-585-514-782-17X; 009-112-965-527-524; 010-871-825-424-606; 011-665-871-789-541; 012-886-755-613-026; 012-978-804-173-708; 013-507-404-965-47X; 013-929-178-842-905; 014-255-721-870-130; 014-306-176-949-237; 014-930-303-059-763; 015-169-522-476-160; 016-303-165-487-275; 018-112-028-872-776; 018-338-757-366-146; 018-633-424-296-938; 019-358-366-563-083; 021-388-541-782-910; 022-304-790-542-067; 022-369-777-842-628; 024-230-198-759-471; 024-513-125-463-047; 024-980-639-709-684; 025-302-119-966-613; 026-895-859-106-523; 027-847-281-426-669; 028-666-494-809-771; 034-480-546-678-251; 035-330-847-069-591; 035-747-043-755-047; 035-864-186-370-825; 039-100-266-277-415; 041-367-690-203-524; 043-871-615-512-760; 044-284-651-137-662; 044-858-555-385-906; 047-077-329-783-399; 049-403-835-198-006; 052-802-334-885-429; 057-522-854-416-007; 061-453-992-092-256; 061-829-988-617-171; 063-610-399-950-802; 064-438-261-806-271; 066-400-343-948-766; 067-342-898-103-787; 067-624-866-824-913; 068-644-831-211-433; 070-831-370-295-149; 071-305-707-663-944; 072-087-175-214-622; 074-169-849-216-088; 076-551-437-187-006; 077-420-060-785-546; 077-923-310-335-527; 080-282-398-091-096; 083-195-498-851-105; 084-373-868-821-17X; 084-496-329-717-218; 085-300-287-100-525; 085-387-077-088-294; 086-728-804-869-695; 088-533-004-919-909; 091-215-382-241-650; 092-202-978-893-282; 095-368-204-309-475; 098-995-003-678-428; 099-085-870-469-302; 099-348-740-030-66X; 100-783-353-606-630; 102-481-128-073-048; 102-856-740-316-542; 104-326-245-111-261; 105-835-681-447-038; 106-377-304-980-209; 108-186-828-579-61X; 110-096-626-049-63X; 112-353-693-995-13X; 113-567-402-081-54X; 114-276-180-925-968; 115-482-499-323-938; 116-870-074-840-922; 117-579-935-628-724; 123-102-496-575-817; 123-352-883-261-940; 125-077-223-753-236; 129-081-706-432-768; 129-332-032-423-649; 133-061-467-308-503; 134-464-531-339-682; 139-735-722-769-347; 141-089-950-543-604; 141-326-607-142-746; 144-360-207-462-685; 144-497-001-886-99X; 145-022-109-857-469; 148-382-488-651-492; 157-523-515-335-413; 179-187-453-671-961; 189-827-467-327-008; 191-337-909-658-577,28,true,cc-by,gold -169-263-742-817-364,"Design for Six Sigma: A Review of the Definitions, Objectives, Activities, and Tools",2022-03-28,2022,journal article,Engineering Management Journal,10429247; 23770643,Informa UK Limited,United Kingdom,A. C. Dzulinski; A. Braghini Junior; D. M. G. Chiroli,"This paper presents a theoretical review of the definitions, objectives, activities, and tools applied in the Design for Six Sigma (DFSS) methodology. It also proposes a theoretical framework that provides a simplified and generic guide, which is not easily found in the scientific literature. The methodology used consists of 3 phases: (a) Systemic review, structured to search and select references on DFSS after 2009; (b) Selection of specific books on DFSS that were cited in the studies found in the systematic review (step “a”); (c) Application of the Bibliometrix scientific mapping tool. Seventeen definitions and objectives of DFSS were enumerated; 9 sets of DFSS structuring phases were observed; a list with 54 main activities and 72 tools that can be applied in DFSS was generated. This proposal aims to bring the DFSS methodology closer to the practical actions of engineering management.",35,2,161,180,Design for Six Sigma; Six Sigma; Structuring; Selection (genetic algorithm); Computer science; Quality (philosophy); Process management; Management science; Manufacturing engineering; Engineering; Systems engineering; Business; Lean manufacturing; Artificial intelligence; Philosophy; Finance; Epistemology,,,,,,http://dx.doi.org/10.1080/10429247.2022.2041964,,10.1080/10429247.2022.2041964,,,0,001-764-105-854-878; 002-671-045-897-326; 003-002-951-830-762; 006-134-041-786-591; 006-304-695-942-417; 008-206-568-617-13X; 009-985-990-929-94X; 011-668-744-880-40X; 012-467-519-541-87X; 013-507-404-965-47X; 015-999-003-054-612; 017-108-436-586-703; 019-135-110-529-203; 020-834-010-401-69X; 021-243-840-283-348; 023-385-689-456-053; 024-554-234-569-140; 026-201-710-435-450; 029-733-255-431-074; 037-051-949-291-725; 038-540-526-076-63X; 043-098-500-387-124; 043-893-977-830-19X; 045-053-689-059-389; 045-996-801-986-443; 050-331-027-791-755; 056-043-487-331-92X; 057-955-282-594-863; 066-698-869-182-915; 067-553-853-744-871; 069-214-139-607-219; 069-821-188-811-309; 071-905-550-158-315; 072-979-167-206-597; 076-316-925-898-560; 080-870-048-778-980; 082-619-598-597-765; 084-601-404-762-898; 097-358-756-751-994; 098-228-570-040-626; 098-763-374-831-281; 102-756-674-384-265; 105-619-909-546-125; 132-577-651-989-362; 168-013-556-423-195; 178-197-289-633-295; 189-931-066-844-530; 192-322-270-211-460,1,false,, -169-339-800-387-365,Comprehensive Science Mapping Analysis [R package bibliometrix version 3.1.4],2021-07-05,2021,,,,,,Massimo Aria; Corrado Cuccurullo,,,,,,Programming language; R package; Science mapping; Computer science,,,,,https://cloud.r-project.org/web/packages/bibliometrix/index.html https://mran.microsoft.com/web/packages/bibliometrix/index.html https://cran.irsn.fr/web/packages/bibliometrix/index.html https://cran.rstudio.com/web/packages/bibliometrix/index.html https://cran.r-project.org/web/packages/bibliometrix/index.html https://cran.auckland.ac.nz/web/packages/bibliometrix/index.html https://cran.uvigo.es/web/packages/bibliometrix/index.html https://mirrors.nics.utk.edu/cran/web/packages/bibliometrix/index.html http://cran.r-project.org/web/packages/bibliometrix/index.html https://cran.ma.ic.ac.uk/web/packages/bibliometrix/index.html,https://cloud.r-project.org/web/packages/bibliometrix/index.html,,,3122109884,,0,,0,false,, -169-475-712-627-257,Liderazgo en instituciones de educación superior: Un análisis a través de Bibliometrix R,,2021,journal article,Ingeniare. Revista chilena de ingeniería,07183305; 07183291,SciELO Agencia Nacional de Investigacion y Desarrollo (ANID),Chile,Liliana Pedraja-Rejas; Emilio Rodríguez-Ponce; Andrés Bernasconi; Camila Muñoz-Fritis,,29,3,472,486,,,,,,http://dx.doi.org/10.4067/s0718-33052021000300472,http://dx.doi.org/10.4067/s0718-33052021000300472,,10.4067/s0718-33052021000300472,3216616036,,0,,4,true,cc-by,gold -169-631-227-606-921,Research on wine flavor: A bibliometric and visual analysis (2003-2022),,2024,journal article,Food Chemistry Advances,2772753x,Elsevier BV,,Yi-Heng Du; Yu-Qi Ye; Zhi-Peng Hao; Xin-Yun Tan; Meng-Qi Ye,"The flavor is a most important characteristic of wine, which is the hotspot of research all the time. The aim of this work was to conduct a meta-analysis to discover the extent of the research on wine flavor that has already been conducted and to understand the trends that point toward future research. Using the Web of Science database, 3812 papers (3519 articles and 293 reviews) on wine flavor published between 2003 and 2022, were identified and submitted to bibliometric and visual analysis using the VOSviewer software, CiteSpace and R-bibliometrix, highlighting the years of publication, the main authors, the institutions, the main journals and the country of origin of both the authors and the scientific production analyzed, as well as the future research topics, hotspots and frontiers etc.. The present work brings forward data in a unique and up-to-date way and provide important clues about research trends and frontiers.",4,,100717,100717,Wine; Web of science; Data science; Bibliometrics; Computer science; Political science; Library science; MEDLINE; Physics; Law; Optics,,,,Basic and Applied Basic Research Foundation of Guangdong Province; National Natural Science Foundation of China; Natural Science Foundation of Shandong Province,,http://dx.doi.org/10.1016/j.focha.2024.100717,,10.1016/j.focha.2024.100717,,,0,000-075-056-108-86X; 001-314-354-214-662; 003-002-774-650-436; 003-816-281-534-376; 005-399-711-379-846; 005-706-968-934-128; 005-880-668-462-839; 006-337-431-093-58X; 007-649-171-861-253; 007-852-425-109-007; 009-301-303-764-742; 011-066-431-817-014; 011-409-971-032-471; 011-593-219-063-782; 012-566-445-846-569; 012-707-838-424-523; 012-792-203-388-855; 013-261-296-086-031; 013-507-404-965-47X; 013-850-807-920-290; 014-160-460-932-96X; 014-786-680-861-811; 017-521-978-878-750; 018-197-180-548-116; 020-109-503-959-382; 020-142-861-309-35X; 020-954-585-936-878; 022-559-906-829-268; 022-943-516-027-880; 023-735-950-263-317; 024-158-114-617-350; 024-390-327-643-807; 024-666-260-464-912; 026-328-859-476-70X; 031-237-680-499-108; 033-615-718-166-711; 034-062-791-599-870; 035-091-820-559-392; 037-527-666-917-290; 040-411-822-787-920; 040-912-361-170-906; 043-505-387-536-508; 045-246-020-095-047; 046-547-268-714-476; 047-762-448-209-176; 048-551-490-612-686; 049-048-960-576-869; 052-634-853-488-775; 052-848-979-640-844; 055-502-225-273-874; 056-589-013-837-771; 057-306-560-145-129; 058-211-466-418-674; 064-400-499-357-900; 064-675-230-381-441; 064-803-780-725-345; 065-613-950-924-937; 067-673-767-241-430; 068-364-473-343-324; 068-565-987-306-185; 069-511-868-544-95X; 070-068-184-347-172; 071-457-330-235-095; 073-715-308-770-915; 074-209-524-798-968; 077-166-812-916-30X; 079-028-016-590-57X; 084-281-698-546-508; 086-608-540-020-535; 088-394-630-441-191; 090-731-522-534-055; 093-667-572-293-160; 094-202-510-030-708; 095-075-741-244-233; 100-217-745-604-582; 103-234-223-348-124; 105-728-418-852-69X; 106-414-112-765-598; 122-277-868-603-654; 128-449-936-032-555; 139-380-652-093-280; 141-770-516-078-794; 151-270-296-287-229; 159-463-516-464-891; 162-726-124-562-388; 165-329-354-577-323; 172-323-300-140-405; 188-952-433-438-347,0,true,"CC BY, CC BY-NC-ND",gold -169-791-108-833-454,The relevance of goal programming for financial portfolio management: a bibliometric and systematic literature review,2024-03-29,2024,journal article,Annals of Operations Research,02545330; 15729338,Springer Science and Business Media LLC,Netherlands,Cinzia Colapinto; Issam Mejri,,346,2,917,943,Relevance (law); Goal programming; Project portfolio management; Portfolio; Systematic review; Computer science; Theory of computation; Management science; Business; Economics; Finance; Operations research; Project management; Political science; Management; MEDLINE; Mathematics; Law; Programming language,,,,,,http://dx.doi.org/10.1007/s10479-024-05911-y,,10.1007/s10479-024-05911-y,,,0,002-052-422-936-00X; 003-258-996-320-140; 004-819-527-814-707; 007-602-674-887-270; 012-640-972-448-645; 013-507-404-965-47X; 013-524-854-219-241; 017-750-600-412-958; 017-883-694-236-949; 019-969-176-090-257; 022-126-766-800-063; 023-403-635-911-15X; 024-325-136-605-962; 024-491-347-287-793; 027-531-312-757-591; 031-809-621-585-875; 035-143-261-130-339; 035-463-601-308-256; 035-841-666-629-013; 037-423-792-391-123; 038-149-120-556-64X; 043-083-290-088-908; 045-993-333-977-461; 046-992-864-415-70X; 047-134-478-431-993; 051-839-185-154-026; 065-478-788-817-324; 066-383-290-040-030; 068-355-649-499-636; 077-199-046-515-443; 081-417-164-950-507; 091-171-703-841-656; 093-186-636-893-601; 116-544-446-054-057; 119-770-239-869-389; 120-369-238-735-703; 122-153-354-258-916; 122-774-115-450-654; 132-936-458-600-61X; 140-032-117-886-523; 141-200-607-894-303; 149-816-925-169-437,4,false,, -170-006-353-290-27X,BiblioBoP: a promising scope of bottom of the pyramid related research through a bibliometric approach,,2022,journal article,International Journal of Bibliometrics in Business and Management,20570538; 20570546,Inderscience Publishers,,Tej Narayan Shaw; Subhadip Banerjee; Debadrita Panda; Sabyasachi Mukhopadhyay,"The emergent field of bottom of the pyramid (BoP) is rapidly evolving in terms of academic publications. It has become imperative to keep track of the publications to find out various information like authors, country, emerging themes, research gap and further scope of research. This paper proposes a bibliometric approach and begins with identifying 1,113 articles on the global perspective from the Scopus database. With the help of Biblioshiny, a web interface for Bibliometrix package, publication evolution over time, identification of current research areas and potential direction of future research and many more have been identified for a refined result of 1,029 papers. This mixed review method involving the quantitative bibliometric analysis and qualitative content analysis indicates a sustainable picture of current research and noteworthy future scope for both global and Indian perspectives. As a whole, this study aims to provide a robust roadmap about the BoP literature.",2,1,75,75,Scope (computer science); Scopus; Top-down and bottom-up design; Data science; Field (mathematics); Bottom of the pyramid; Perspective (graphical); Bibliometrics; Pyramid (geometry); Identification (biology); Computer science; Political science; Regional science; Sociology; World Wide Web; Business; Marketing; MEDLINE; Optics; Artificial intelligence; Physics; Botany; Mathematics; Software engineering; Pure mathematics; Law; Biology; Programming language,,,,,,http://dx.doi.org/10.1504/ijbbm.2022.10046335,,10.1504/ijbbm.2022.10046335,,,0,,0,false,, -170-036-251-697-957,Metabolic syndrome and bladder cancer risk: a comprehensive evidence synthesis combining bibliometric and meta-analysis approaches.,2025-05-21,2025,journal article,BMC urology,14712490,Springer Science and Business Media LLC,United Kingdom,Yi Yuan; Tongpeng Liu; Yu Yao; Qingyue Ma; Lijiang Sun; Guiming Zhang,"This study employed bibliometric analysis to explore global research on metabolic syndrome (MetS) and bladder cancer (BC), focusing on characteristics and research trends. Additionally, a meta-analysis was conducted to comprehensively evaluate the association between MetS and its components with the risk of BC.; We conducted a comprehensive search of publications from 2002 to 2022 in the Web of Science Core Collection (WoSCC). Visualization analysis was performed using the Open Scientometrics Data Analysis and Visualization Platform, VOSviewer software and the R package ""bibliometrix"". For the meta-analysis, data from PubMed, Embase and the Cochrane Library up to March 22, 2022, were utilized. Literature from PubMed, Embase, Cochrane and Web of Science up to March 25, 2022, were retrieved, and data extraction was independently performed by two authors. A random-effects model was used to calculate pooled odds ratios (ORs) and 95% confidence intervals (95% CIs). Meta-analysis was conducted using RevMan 5.4 software.; In the bibliometric analysis, 147 papers were included, and information on countries, institutions, authors, journals and keywords from Web of Science was analyzed and visualized. For the meta-analysis, 11 studies involving 665,164 patients were included. The pooled analysis of six case-control studies showed that patients with MetS had a higher risk of BC compared to the non-MetS control group (OR = 1.62, 95% CI: 1.08-2.43, P < 0.01). Analysis of MetS components revealed that diabetes (OR = 0.44, 95% CI: 0.32-0.61, P < 0.01), low high-density lipoprotein (HDL) (OR = 0.29, 95% CI: 0.19-0.44, P < 0.01) and high triglycerides (OR = 0.59, 95% CI: 0.39-0.88, P < 0.01) were associated with an increased risk of BC. In contrast, hypertension (OR = 0.84, 95% CI: 0.62-1.12, P > 0.05) and obesity (OR = 0.8, 95% CI: 0.44-1.45, P > 0.05) showed no significant association with BC risk.; This study provided valuable insights into the association between MetS and BC risk by identifying past research trends and hotspots. MetS and its components, such as diabetes, low HDL and high triglycerides, were associated with an increased risk of BC.; © 2025. The Author(s).",25,1,132,,Medicine; Meta-analysis; Bladder cancer; Metabolic syndrome; MEDLINE; Oncology; Urology; Internal medicine; Cancer; Obesity; Political science; Law,Bladder Cancer; Cancer Risk; Diabetes; Dyslipidemia; Metabolic Syndrome,Metabolic Syndrome/complications; Urinary Bladder Neoplasms/epidemiology; Humans; Bibliometrics; Risk Factors,,Natural Science Foundation of Shandong Province (ZR2021MH354),,http://dx.doi.org/10.1186/s12894-025-01812-9,40394622,10.1186/s12894-025-01812-9,,PMC12093781,0,005-664-726-205-528; 006-461-680-317-503; 007-123-860-010-909; 011-291-416-015-882; 012-227-984-891-397; 016-440-952-680-614; 017-458-437-591-707; 019-428-921-947-248; 021-845-849-194-542; 022-973-869-237-178; 026-268-078-517-968; 027-479-398-658-248; 028-551-947-544-359; 032-951-555-509-21X; 035-517-280-884-455; 035-914-234-983-080; 040-463-548-235-422; 041-301-796-551-891; 043-133-434-962-08X; 048-598-127-256-339; 054-102-521-454-208; 055-973-235-992-451; 069-078-309-646-234; 070-461-378-388-547; 071-758-331-553-879; 084-553-957-156-595; 085-156-487-351-915; 106-100-019-904-969; 106-588-312-941-664; 119-208-124-226-457; 122-555-831-089-046; 126-862-874-009-435; 149-802-545-982-20X; 157-842-181-562-293; 163-115-141-698-125; 177-242-758-239-260,0,true,"CC BY, CC0",gold -170-081-429-360-837,Imaging genomics of cancer: a bibliometric analysis and review.,2025-03-04,2025,journal article,Cancer imaging : the official publication of the International Cancer Imaging Society,14707330; 17405025,Springer Science and Business Media LLC,United Kingdom,Xinyi Gou; Aobo Feng; Caizhen Feng; Jin Cheng; Nan Hong,"Imaging genomics is a burgeoning field that seeks to connections between medical imaging and genomic features. It has been widely applied to explore heterogeneity and predict responsiveness and disease progression in cancer. This review aims to assess current applications and advancements of imaging genomics in cancer.; Literature on imaging genomics in cancer was retrieved and selected from PubMed, Web of Science, and Embase before July 2024. Detail information of articles, such as systems and imaging features, were extracted and analyzed. Citation information was extracted from Web of Science and Scopus. Additionally, a bibliometric analysis of the included studies was conducted using the Bibliometrix R package and VOSviewer.; A total of 370 articles were included in the study. The annual growth rate of articles on imaging genomics in cancer is 24.88%. China (133) and the USA (107) were the most productive countries. The top 2 keywords plus were ""survival"" and ""classification"". The current research mainly focuses on the central nervous system (121) and the genitourinary system (110, including 44 breast cancer articles). Despite different systems utilizing different imaging modalities, more than half of the studies in each system employed radiomics features.; Publication databases provide data support for imaging genomics research. The development of artificial intelligence algorithms, especially in feature extraction and model construction, has significantly advanced this field. It is conducive to enhancing the related-models' interpretability. Nonetheless, challenges such as the sample size and the standardization of feature extraction and model construction must overcome. And the research trends revealed in this study will guide the development of imaging genomics in the future and contribute to more accurate cancer diagnosis and treatment in the clinic.; © 2025. The Author(s).",25,1,24,,Medicine; Genomics; Cancer; Radiogenomics; Cancer imaging; Computational biology; Medical physics; Bioinformatics; Radiomics; Data science; Genome; Internal medicine; Radiology; Genetics; Computer science; Gene; Biology,Bibliometric analysis; Cancer; Imaging genomics; Review,Humans; Bibliometrics; Neoplasms/genetics; Imaging Genomics/methods; Genomics,,,https://cancerimagingjournal.biomedcentral.com/counter/pdf/10.1186/s40644-025-00841-9 https://doi.org/10.1186/s40644-025-00841-9,http://dx.doi.org/10.1186/s40644-025-00841-9,40038813,10.1186/s40644-025-00841-9,,PMC11877899,0,001-924-040-657-389; 002-924-520-001-019; 003-886-539-325-568; 006-027-215-948-826; 006-113-781-401-092; 006-920-908-445-545; 007-404-252-527-358; 008-521-861-254-104; 010-993-140-189-442; 012-292-831-894-686; 015-093-973-546-887; 015-526-175-497-444; 016-557-075-470-461; 019-736-191-308-720; 021-155-481-410-658; 022-391-429-374-46X; 022-885-881-421-074; 024-015-417-418-406; 028-904-334-055-553; 032-408-167-646-736; 034-943-061-548-019; 036-312-512-845-058; 038-875-274-775-569; 039-414-836-353-275; 040-209-538-663-681; 041-049-026-708-096; 042-620-612-171-291; 043-545-738-453-242; 044-583-912-739-865; 044-800-962-391-199; 047-753-778-646-171; 047-763-125-199-617; 048-374-129-163-811; 051-794-388-535-869; 053-261-385-957-442; 057-302-792-235-141; 060-016-775-286-511; 060-165-377-776-362; 068-146-334-393-422; 070-279-103-885-535; 071-821-571-558-563; 074-101-856-163-198; 075-895-449-113-760; 079-344-420-132-700; 081-788-064-472-467; 082-243-253-947-851; 084-870-400-961-350; 085-289-443-884-890; 088-478-556-799-942; 088-667-978-126-206; 089-900-561-667-036; 092-062-550-269-321; 094-960-994-221-799; 095-089-929-015-544; 102-079-321-115-38X; 102-193-379-614-260; 104-231-875-626-268; 106-986-402-754-399; 110-645-199-918-763; 117-506-971-631-878; 118-033-861-308-091; 118-918-246-552-613; 119-166-235-309-754; 119-887-112-147-556; 139-864-171-915-31X; 140-271-760-953-850; 146-047-511-786-387; 156-246-369-552-815; 156-437-411-523-383; 157-067-287-940-024; 157-449-281-694-831; 157-969-114-162-60X; 170-408-988-638-737; 171-142-090-951-242; 173-819-806-608-98X; 174-586-728-920-389; 175-661-463-177-860; 185-112-547-724-885; 187-760-233-607-756; 188-842-086-488-413; 190-629-024-327-736; 196-350-682-496-283,0,true,"CC BY, CC0",gold -170-197-230-297-783,Estrategia en ciudades inteligentes e inclusión social del adulto mayor,2021-02-26,2021,journal article,PAAKAT: Revista de Tecnología y Sociedad,20073607,Universidad de Guadalajara,,Édgar Alejandro López López; Erick Leobardo Alvarez Aros,"Smart cities are increasingly necessary in today's society, however the social inclusion of the elderly within these seems a forgotten issue that needs to be considered for the construction of an inclusive society. The objective of this research is to explore the social inclusion of the elderly in smart cities, as well as their evolution, scientometric characteristics and trends by means of a bibliometric analysis. The work analyzes bibliometric metadata of 244 Scopus documents, published from 2010 to 2020 using Software R, Bibliometrix and Biblioshiny. The conclusions indicate that a growing interest is maintained over time, and this is perceived mainly in conferences; in addition, thematic trends reveal elements such as the internet of things, design and implementation, and e-commerce among others. Likewise, the emergence of the term inclusive smart city was evidenced, which considers the integration into society of vulnerable groups. It is expected that this work will serve as a reference for an inclusive design of smart cities.",11,20,1,29,Sociology; Work (electrical); Smart city; Bibliometric analysis; Public relations; Term (time); Internet of Things; Scopus; Metadata; Universal design,,,,,https://dialnet.unirioja.es/descarga/articulo/7857519.pdf http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2007-36072021000100002 http://www.udgvirtual.udg.mx/paakat/index.php/paakat/article/download/543/pdf https://dialnet.unirioja.es/servlet/articulo?codigo=7857519 http://www.udgvirtual.udg.mx/paakat/index.php/paakat/article/view/543 http://www.scielo.org.mx/pdf/prts/v11n20/2007-3607-prts-11-20-e543.pdf,http://dx.doi.org/10.32870/pk.a11n20.543,,10.32870/pk.a11n20.543,3136696983,,0,,4,true,cc-by-nc,gold -170-284-136-077-739,Village chicken production and food security: a two-decade bibliometric analysis of global research trends.,2022-08-02,2022,journal article,Agriculture & food security,20487010,Springer Science and Business Media LLC,United Kingdom,Emrobowansan Monday Idamokoro; Yiseyon Sunday Hosu,"The present study aimed to reveal outputs of research works on village chicken production as a tool to combat food insecurity, taking into account the recurring challenge posed by food shortage and high rise in hunger among vulnerable people of several countries.; On aggregate, 104 publications were obtained in a BibTeX design for analysis using bibliometric package in R studio. The obtained data comprised, but not limited to authors, citations, institutions, key words and journals. Published articles on village chicken production with relation to food security retrieved from web of science (WOS) and Scopus data banks were utilized with a rise in research publications of a yearly growth of 12.93% during the study period. With regard to country, USA was ranked first with an aggregate sum of publications (n = 16), and a huge global academic influence with most top article citations (n = 509). The frequently used authors' keywords in this studied research area were food security (n = 23), poultry (n = 9), chickens (n = 7), backyard poultry (n = 5), gender (n = 4), which all together created a hint on related studies on village chicken production and food security.; The present study provides a worldwide situation that traverse the intellectual quandary on village chicken production and food security research, and a direction for further researches in this field. It is very vital to emphasize that the current study only dealt with principal areas of village chicken production as related to food security research, hence, it is projected that new empirical research and prospective research findings would afford new knowledge and insight on village chicken production as a means to address food security challenges as new studies evolves.; © The Author(s) 2022.",11,1,40,,Food security; Scopus; Production (economics); Web of science; Economic shortage; Consumption (sociology); Agricultural economics; Business; Food processing; Political science; Geography; Agricultural science; Marketing; Socioeconomics; Agriculture; Social science; Economics; Sociology; Biology; Linguistics; Philosophy; Archaeology; MEDLINE; Government (linguistics); Law; Macroeconomics,Backyard chicken; Bibliometric evaluation; Farming; Food security; Vulnerable people,,,,https://agricultureandfoodsecurity.biomedcentral.com/counter/pdf/10.1186/s40066-022-00379-0 https://doi.org/10.1186/s40066-022-00379-0,http://dx.doi.org/10.1186/s40066-022-00379-0,35938061,10.1186/s40066-022-00379-0,,PMC9344447,0,001-232-291-704-349; 001-554-877-975-914; 002-052-422-936-00X; 002-983-521-978-761; 006-906-933-606-143; 008-446-469-027-700; 008-471-561-228-243; 009-839-334-676-168; 011-391-939-662-665; 012-550-143-005-039; 013-507-404-965-47X; 014-769-154-847-96X; 014-812-893-775-913; 018-018-785-295-573; 022-853-019-464-378; 024-824-860-545-549; 031-551-674-581-135; 033-428-233-485-841; 033-777-638-324-611; 035-330-847-069-591; 036-656-168-693-890; 041-561-239-580-826; 043-627-211-692-30X; 044-042-866-208-120; 044-481-666-575-588; 050-552-987-586-715; 051-865-643-777-765; 053-104-475-700-596; 054-439-051-844-343; 056-441-439-197-934; 059-642-270-769-342; 064-880-308-426-113; 067-456-603-759-590; 068-439-084-657-120; 073-008-010-322-076; 074-373-475-017-778; 076-792-449-044-149; 077-553-574-890-852; 083-643-200-062-290; 085-862-951-409-905; 087-172-326-777-336; 088-908-268-737-277; 090-476-872-676-699; 096-289-955-945-318; 106-402-045-540-824; 111-685-128-869-717; 127-048-745-950-798; 127-645-778-235-147; 142-608-256-821-705; 178-935-941-875-300,7,true,"CC BY, CC0",gold -170-398-339-521-110,Comparison of nanotechnology research for coronaviruses and influenza from 2000 to 2022,2023-09-06,2023,journal article,Journal of Nanoparticle Research,13880764; 1572896x,Springer Science and Business Media LLC,Netherlands,Thomas S. Woodson; Swaneet Jha,,25,9,,,Pandemic; Coronavirus disease 2019 (COVID-19); Nanomedicine; Middle East respiratory syndrome; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Coronavirus; Nanotechnology; Virology; Medicine; Disease; Infectious disease (medical specialty); Materials science; Nanoparticle; Outbreak; Pathology,,,,National Science Foundation; National Science Foundation,,http://dx.doi.org/10.1007/s11051-023-05831-1,,10.1007/s11051-023-05831-1,,,0,000-898-917-370-462; 002-362-222-675-814; 005-194-638-572-033; 006-706-099-693-671; 007-000-236-848-476; 009-286-240-384-618; 010-126-294-070-73X; 013-358-678-935-028; 016-814-980-495-698; 018-559-221-080-181; 026-888-554-240-400; 031-620-773-615-552; 033-115-758-624-878; 037-753-667-642-298; 039-318-983-377-939; 041-679-586-558-088; 042-805-221-786-492; 048-043-567-736-492; 051-905-317-081-07X; 060-352-736-869-75X; 064-674-585-297-201; 066-225-105-467-435; 067-995-910-345-884; 068-941-283-018-878; 069-689-861-851-808; 071-878-836-294-733; 086-000-260-792-076; 094-012-436-657-299; 097-936-505-274-902; 098-157-781-016-583; 098-330-637-742-835; 099-597-593-524-383; 102-661-597-954-313; 122-110-182-435-663; 128-907-324-795-434; 130-209-991-424-438; 133-495-109-324-894; 137-508-108-286-078; 176-334-491-054-225,0,false,, -170-590-739-765-157,Application of Bibliometrix App in the Context of Digital Transformation and Automation of SCM and Logistics Sector,2025-02-17,2025,book chapter,"International Perspectives on Equality, Diversity and Inclusion",20512333; 20512341,Emerald Publishing Limited,,Daniil Ilyich Golubtsov; Damian Kedziora; Rysty Bozmanaevna Sartova; Paweł Kędziora,"The main objective of the study was to identify main trends, research directions and important authors in the field of supply chain management (SCM) and logistics in the context of digital transformation and automation through the application of bibliometric analysis. The study is based on the analysis of academic publications and research studies covering the topics of digital transformation (incl. automation) of the logistics sector and SCM. For this purpose, bibliometric methods are applied, including keyword frequency analysis, identification of the most cited sources and authors. The chapter identifies main trends and research directions in the field of digital transformation of the logistics sector and SCM. Also, the most influential sources and authors making significant contributions to the development of this field are identified. Top 10 best authors, citations and documents got illustrated. The results of the study can be useful for researchers involved in the digital transformation of the logistics sector and SCM, as well as for practitioners developing strategies and solutions in the field of logistics and SCM. The bibliometric analysis provides valuable information on status and trends in research on digital transformation of the logistics sector and SCM (444 documents analyzed), which can be useful for further research and strategy development in this area. Based on the results of the study, it was possible to identify that the increase in research on digital transformation of the logistics sector and SCM is related to the emergence and subsequent epidemic of the COVID-19 virus.",,,47,62,Automation; Context (archaeology); Digital transformation; Transformation (genetics); Business; Computer science; Manufacturing engineering; Process management; Engineering; World Wide Web; Geography; Mechanical engineering; Chemistry; Biochemistry; Archaeology; Gene,,,,,,http://dx.doi.org/10.1108/s2051-23332025000011a004,,10.1108/s2051-23332025000011a004,,,0,,0,false,, -170-594-622-571-63X,"The impact of social isolation and loneliness on cardiovascular disease risk factors: a systematic review, meta-analysis, and bibliometric investigation.",2024-06-04,2024,journal article,Scientific reports,20452322,Springer Science and Business Media LLC,United Kingdom,Osama Albasheer; Siddig Ibrahim Abdelwahab; Mohammad R Zaino; Ahmed Abdallah Ahmed Altraifi; Nasser Hakami; Ehab I El-Amin; Mohammed M Alshehri; Saeed M Alghamdi; Abdulfattah S Alqahtani; Aqeel M Alenazi; Bader Alqahtani; Ahmed Alhowimel; Shadab Uddin; Husam Eldin Elsawi Khalafalla; Isameldin E Medani,"Data on the association between social isolation, loneliness, and risk of incident coronary heart disease (CVD) are conflicting. The objective of this study is to determine the relationship between social isolation and loneliness, and the risk of developing cardiovascular disease (CVD) in middle age and elderly using meta-analysis. The purpose of the bibliometric analysis is to systematically evaluate the existing literature on the relationship between social isolation, loneliness, and the risk of developing cardiovascular disease (CVD) in middle-aged and elderly individuals. A comprehensive search through four electronic databases (MEDLINE, Google Scholar, Scopus, and Web of Science) was conducted for published articles that determined the association between social isolation and/or loneliness and the risk of developing coronary heart disease from June 2015 to May 2023. Two independent reviewers reviewed the titles and abstracts of the records. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline to conduct the systematic review and meta-analysis. Data for the bibliometric analysis was obtained from the Scopus database and analyzed using VOSviewer and Bibliometrix applications. Six studies involving 104,511 patients were included in the final qualitative review and meta-analysis after screening the records. The prevalence of loneliness ranged from 5 to 65.3%, and social isolation ranged from 2 to 56.5%. A total of 5073 cardiovascular events were recorded after follow-up, ranging between 4 and 13 years. Poor social relationships were associated with a 16% increase in the risk of incident CVD (Hazard Ratio of new CVD when comparing high versus low loneliness or social isolation was 1.16 (95% Confidence Interval (CI) 1.10-1.22). The bibliometric analysis shows a rapidly growing field (9.77% annual growth) with common collaboration (6.37 co-authors/document, 26.53% international). The US leads research output, followed by the UK and Australia. Top institutions include University College London, Inserm, and the University of Glasgow. Research focuses on ""elderly,"" ""cardiovascular disease,"" and ""psychosocial stress,"" with recent trends in ""mental health,"" ""social determinants,"" and ""COVID-19"". Social isolation and loneliness increase the risk of and worsen outcomes in incident cardiovascular diseases. However, the observed effect estimate is small, and this may be attributable to residual confounding from incomplete measurement of potentially confounding or mediating factors. The results of the bibliometric analysis highlight the multidimensional nature of CVD research, covering factors such as social, psychological, and environmental determinants, as well as their interplay with various demographic and health-related variables.",14,1,12871,,Loneliness; Meta-analysis; Scopus; Social isolation; Systematic review; Medicine; Disease; Guideline; MEDLINE; Social support; Gerontology; Psychology; Internal medicine; Psychiatry; Pathology; Biology; Biochemistry; Psychotherapist,Bibliometrics; Cardiovascular disease; Loneliness; Meta-analysis; Social health; Social isolation,Humans; Loneliness/psychology; Social Isolation/psychology; Bibliometrics; Cardiovascular Diseases/epidemiology; Risk Factors; Aged; Middle Aged; Male; Female,,,https://www.nature.com/articles/s41598-024-63528-4.pdf https://doi.org/10.1038/s41598-024-63528-4,http://dx.doi.org/10.1038/s41598-024-63528-4,38834606,10.1038/s41598-024-63528-4,,PMC11150510,0,002-052-422-936-00X; 002-841-306-224-728; 002-948-753-727-618; 004-840-645-715-917; 011-863-641-042-757; 011-935-265-277-092; 013-507-404-965-47X; 017-037-873-028-915; 023-088-450-697-09X; 024-539-694-063-065; 025-409-172-719-064; 026-743-226-670-009; 029-358-116-457-053; 031-790-995-128-524; 034-303-123-415-241; 034-619-886-228-621; 037-637-957-165-698; 039-348-539-340-002; 039-799-822-284-520; 043-962-907-006-206; 044-300-587-565-01X; 045-416-413-742-937; 045-453-059-665-897; 052-121-487-507-951; 055-008-369-647-093; 055-701-549-054-450; 056-341-256-654-516; 062-431-809-925-977; 066-584-195-519-861; 068-371-633-724-376; 076-498-170-063-038; 086-622-683-354-779; 088-180-158-306-135; 092-604-720-063-128; 094-175-947-488-286; 102-197-289-295-911; 106-404-317-930-682; 121-062-690-307-983; 122-468-823-139-191; 148-277-726-469-879; 160-252-645-547-082; 161-373-734-592-739; 172-149-619-340-766,13,true,"CC BY, CC BY-NC-ND",gold -170-828-598-171-511,Analyzing Research Trends in Green Consumerism,2023-06-30,2023,book chapter,"Advances in Marketing, Customer Relationship Management, and E-Services",23275502; 23275529,IGI Global,,Pınar Yürük-Kayapınar; Burcu Ören Özer,"The aim of this chapter is to engage with the concepts of green consumer and green consumerism and to perform a bibliometric analysis of the related publications. To this end, the studies are examined in WoS and Scopus between 1965 and 2023, using the keywords “green consumer” and “green consumerism.” The study imposed certain constraints, resulting in the acquisition of a total of 7238 articles derived from 1728 sources. For this analysis, the Bibliometrix R Package Program was applied. An initial phase of the study was to conduct a descriptive analysis to provide an overview of the data. The subsequent phase involved examining several elements: the number of publications and citations by year; the most published journals on these subjects and their H-index values; the number of publications and H-index values of the authors; productivity of countries; most frequently used words; and collaboration networks of words, countries, and authors. Additionally, a factor analysis was carried out within the scope of the study to facilitate the observation of cluster formations.",,,49,76,Consumerism; Scopus; Scope (computer science); Index (typography); Descriptive statistics; Productivity; Social science; Regional science; Marketing; Political science; Geography; Sociology; Statistics; Business; Economics; Mathematics; Computer science; Economic growth; World Wide Web; Law; MEDLINE; Programming language,,,,,,http://dx.doi.org/10.4018/978-1-6684-8140-0.ch003,,10.4018/978-1-6684-8140-0.ch003,,,0,001-489-832-029-31X; 009-317-858-011-361; 010-168-316-482-221; 017-635-780-559-645; 017-750-600-412-958; 018-231-132-350-953; 035-854-849-551-880; 045-320-019-290-809; 046-992-864-415-70X; 048-777-931-195-091; 054-816-760-060-315; 065-749-270-886-220; 081-847-701-576-574; 090-596-432-586-741; 091-809-819-424-424; 094-894-403-096-285; 109-624-509-149-843; 126-873-516-963-37X,0,false,, -171-145-596-151-780,"Current status, evolutionary path, and development trends of low-carbon technology innovation: a bibliometric analysis",2023-07-27,2023,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,Jianwei Xu; Shuxin Liu,,26,9,24151,24182,Bibliometrics; Field (mathematics); Metadata; Corporate governance; Data science; Dual (grammatical number); Regional science; Sustainable development; Political science; Knowledge management; Computer science; Business; Geography; Library science; World Wide Web; Art; Mathematics; Literature; Finance; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1007/s10668-023-03640-z,,10.1007/s10668-023-03640-z,,,0,001-719-026-803-199; 002-085-274-794-396; 002-590-032-201-92X; 003-477-743-955-180; 004-202-011-265-209; 007-617-495-940-998; 009-286-240-384-618; 010-402-266-574-621; 012-979-388-903-402; 013-010-823-816-82X; 013-417-183-363-90X; 013-524-854-219-241; 014-273-763-505-173; 016-999-636-361-416; 017-891-400-253-461; 022-019-942-828-417; 022-113-032-235-234; 024-585-797-088-553; 024-641-751-182-599; 027-170-656-363-712; 027-406-540-345-844; 028-039-124-434-367; 028-666-494-809-771; 028-839-465-819-201; 032-292-990-257-970; 032-648-541-430-410; 032-862-838-813-444; 034-609-535-891-668; 037-265-400-915-40X; 039-370-236-959-52X; 039-861-195-349-982; 041-931-695-820-294; 042-911-354-037-478; 043-167-613-547-813; 045-540-591-165-392; 046-374-119-472-212; 050-252-928-690-470; 050-893-374-534-416; 052-152-211-987-423; 052-832-436-694-452; 053-344-968-672-602; 056-913-328-377-88X; 060-096-277-544-365; 061-421-259-900-488; 062-420-185-689-801; 062-586-309-986-139; 063-394-455-900-057; 065-714-258-808-641; 067-565-431-298-005; 067-850-895-306-475; 068-145-229-113-420; 068-259-085-977-283; 069-240-211-118-970; 069-702-468-061-926; 070-177-738-806-709; 074-954-398-188-316; 079-250-822-438-932; 084-273-472-375-662; 086-744-974-559-008; 094-033-433-512-337; 094-177-617-833-47X; 095-485-544-404-64X; 101-966-423-785-872; 105-075-034-317-916; 106-028-633-675-736; 114-156-498-597-97X; 122-415-544-444-960; 123-016-343-445-711; 125-441-864-624-766; 127-567-704-379-155; 129-187-587-833-432; 133-857-570-440-397; 139-082-571-597-57X; 141-264-364-431-090; 158-827-554-177-744; 161-646-638-264-285; 162-784-352-048-669; 187-144-263-114-486; 192-387-394-958-897,8,false,, -171-796-099-938-83X,Bibliometric Analysis of the Structure and Evolution of Research on Assisted Migration,2022-03-28,2022,journal article,Current Forestry Reports,21986436,Springer Science and Business Media LLC,,Lahcen Benomar; Raed Elferjani; Jill Hamilton; Greg A. O'Neill; Said Echchakoui; Yves Bergeron; Mebarek Lamara,"AbstractPurpose of ReviewAssisted migration is increasingly proposed as a proactive management strategy to mitigate the consequences of maladaptation predicted under climate change. Exploring the social and academic structure of the field, its research gaps, and future research directions can help further the understanding and facilitate the implementation of assisted migration strategies. Here we used bibliometric analysis to examine the intellectual, social, and conceptual structures of assisted migration research to identify gaps and opportunities for future research. Bibliometric data based on publications on assisted migration were collected from Scopus and Web of Science databases using assisted migration and climate change or their synonyms as queries. Metadata were merged, processed and several networks were constructed.Recent FindingsCo-citation and keyword co-occurrence networks identified three major clusters focused on (i) theory and risk of assisted migration of threatened and endangered species, (ii) impact of climate change on realized and fundamental climate and geographic niches, and (iii) assisted population migration. Collaboration network analysis identified three social core hubs: North America, Europe, and Australia, with the USA and Canada being the most productive and the most collaborative countries.SummaryWe conclude that future research is expected to concern mainly the assessment of physiological response of species and populations to extreme climate events such as drought and frost, and the contribution of non-climatic factors and biotic interactions in local adaptation and population performance under climate change. Social core hubs distinguished in this work can be used to identify potential international research and training collaborators necessary to address gaps and challenges underlying assisted migration implementation.",8,2,199,213,Scopus; Climate change; Maladaptation; Social network analysis; Population; Geography; Environmental resource management; Metadata; Conceptual framework; Adaptation (eye); Threatened species; Data science; Ecology; Social media; Regional science; Political science; Computer science; Sociology; Social science; Biology; Environmental science; World Wide Web; Genetics; Demography; MEDLINE; Neuroscience; Habitat; Law,,,,Fondation de l’Université du Québec en Abitibi-Témiscamingue,https://link.springer.com/content/pdf/10.1007/s40725-022-00165-y.pdf https://doi.org/10.1007/s40725-022-00165-y,http://dx.doi.org/10.1007/s40725-022-00165-y,,10.1007/s40725-022-00165-y,,,0,002-557-146-491-510; 003-423-430-162-768; 010-524-319-521-132; 013-507-404-965-47X; 013-582-256-718-441; 015-523-622-700-501; 016-655-706-124-813; 017-750-600-412-958; 019-706-336-089-489; 020-596-703-248-201; 021-391-074-132-990; 022-050-154-142-786; 022-395-352-047-206; 023-250-589-620-348; 024-475-938-203-942; 025-781-688-352-17X; 026-463-616-490-218; 028-842-776-614-614; 037-499-214-526-234; 038-522-431-225-699; 039-164-697-034-282; 040-569-663-634-301; 041-723-690-925-066; 043-605-540-403-68X; 043-681-817-573-388; 045-422-273-148-899; 047-134-478-431-993; 047-256-513-390-820; 049-273-294-026-582; 050-133-457-247-162; 051-343-525-773-423; 054-642-469-834-031; 055-427-371-463-783; 056-665-516-805-757; 059-215-733-809-114; 059-712-017-197-038; 060-771-260-860-472; 065-649-942-447-012; 066-461-027-920-218; 067-222-533-898-840; 068-926-716-319-698; 069-145-184-335-770; 071-988-813-089-857; 075-697-660-728-288; 077-430-938-917-586; 079-278-714-415-834; 086-359-684-264-518; 097-406-243-076-843; 102-400-192-806-608; 109-998-503-270-200; 115-613-371-837-232; 115-922-829-215-638; 122-415-544-444-960; 125-917-485-906-289; 127-645-778-235-147; 129-679-169-623-193; 133-399-359-659-179; 134-818-633-155-927; 141-200-607-894-303; 147-473-947-926-30X; 168-602-152-241-913; 196-353-490-367-755,26,true,cc-by,hybrid -171-956-237-146-276,Performance analysis of hospitals in Australia and its peers: a systematic and critical review,2024-06-29,2024,journal article,Journal of Productivity Analysis,0895562x; 15730441,Springer Science and Business Media LLC,Netherlands,Zhichao Wang; Bao Hoang Nguyen; Valentin Zelenyuk,"AbstractAlong with the development of productivity and efficiency analysis techniques, extensive research on the performance of hospitals has been conducted in the last few decades. In this article, we conduct a systematic review supported by a series of bibliometric analyses to obtain a panoramic perspective of the research about the productivity and efficiency of hospitals—a cornerstone of the healthcare system—with a focus on Australia and its peers, i.e., the UK, Canada, New Zealand, and Hong Kong. We focus on the bibliometric data in Scopus from 1970 to 2023 and provide a qualitative and critical analysis of major methods and findings in selected published journal articles.",62,2,139,173,Econometrics; Economics; Psychology,,,,,,http://dx.doi.org/10.1007/s11123-024-00729-z,,10.1007/s11123-024-00729-z,,,0,000-429-162-272-925; 000-759-592-882-995; 001-544-151-870-321; 002-052-422-936-00X; 003-667-510-759-581; 003-869-063-292-240; 004-819-527-814-707; 006-216-778-209-034; 006-623-778-984-055; 007-015-084-005-77X; 008-029-416-709-639; 009-248-056-740-654; 009-286-240-384-618; 009-548-889-122-409; 011-235-937-752-953; 011-561-977-824-61X; 011-839-216-179-680; 012-540-442-623-815; 013-507-404-965-47X; 013-737-518-856-70X; 014-337-828-826-622; 014-951-219-133-038; 017-023-518-086-70X; 017-895-990-187-57X; 023-960-959-854-341; 024-945-937-399-561; 026-100-725-701-456; 026-194-639-089-475; 026-909-680-098-433; 027-356-796-030-659; 027-514-449-542-706; 028-905-622-018-276; 030-023-569-728-291; 030-693-236-954-322; 031-221-334-601-476; 033-838-104-279-875; 034-340-428-344-678; 034-442-522-368-681; 034-571-319-658-14X; 037-162-053-811-953; 038-065-747-019-540; 038-130-405-356-713; 038-453-781-724-846; 038-694-126-747-993; 040-992-465-128-393; 044-741-362-285-029; 048-893-291-147-427; 049-230-958-827-105; 050-460-819-286-424; 050-636-728-286-601; 051-310-754-126-026; 051-454-179-615-423; 052-491-175-666-388; 053-058-835-806-606; 053-598-695-896-482; 054-818-565-070-154; 055-565-806-830-403; 056-410-370-793-735; 056-696-213-130-926; 057-141-370-995-63X; 057-168-131-151-595; 059-629-535-913-578; 060-110-039-971-60X; 061-252-831-510-751; 061-549-812-643-636; 061-823-788-664-38X; 061-894-183-958-826; 062-466-737-663-057; 063-528-336-713-700; 063-820-055-344-724; 063-927-491-414-012; 064-400-499-357-900; 064-496-855-404-662; 064-782-708-036-262; 065-306-750-072-450; 065-583-915-784-890; 065-721-190-000-966; 070-357-991-986-000; 070-937-502-515-883; 074-170-771-931-898; 074-972-353-338-340; 077-036-465-776-158; 077-111-484-173-835; 078-237-515-305-82X; 079-805-348-676-269; 081-786-863-403-215; 081-803-974-621-735; 082-906-367-637-469; 083-328-629-453-85X; 083-381-044-953-974; 085-300-287-100-525; 085-578-245-333-44X; 088-817-977-986-889; 088-857-274-601-942; 089-425-788-010-354; 090-956-030-115-572; 091-608-670-272-58X; 092-024-876-981-290; 092-355-978-127-235; 095-258-654-450-233; 096-835-429-148-971; 098-138-318-081-267; 098-218-233-833-706; 100-607-112-002-358; 100-641-254-853-78X; 101-358-049-969-073; 101-675-526-170-643; 104-465-940-408-446; 111-561-331-326-000; 111-940-551-174-280; 114-241-254-638-639; 118-049-170-428-12X; 118-433-243-232-790; 122-631-998-355-379; 123-717-470-871-483; 127-134-528-683-700; 127-490-222-119-374; 137-902-470-860-242; 148-810-303-094-326; 151-374-013-752-001; 164-799-963-167-186; 169-431-243-018-963; 169-976-354-907-448; 170-907-672-175-832; 185-432-234-773-398; 192-714-794-811-339; 193-343-687-775-981; 197-463-460-129-573,2,true,cc-by,hybrid -171-976-394-981-003,Global research trends and developments in female infertility: a systematic bibliometric analysis and network visualization of 9288 studies,2025-05-07,2025,journal article,Middle East Fertility Society Journal,20903251; 11105690,Springer Science and Business Media LLC,Egypt,Tauseef Ahmad; Mukhtiar Baig; Sahar Shafik Othman; Shahad Abduljalil Abuhamael,"Abstract; ; Objective; Female infertility has remained a significant health issue over the years. This study was conducted to analyze the key bibliometric indicators and plot the global research on female infertility.; ; ; Methods; A systematic bibliometric study was designed. The Web of Science Core Collection and MEDLINE databases were used to retrieve the relevant studies on the subject. The following search keywords were used: “female infertility” OR “women infertility” OR “woman infertility” OR “fertility in women” OR “fertility in woman” OR “infertile women” OR “infertile woman” OR “sterile women” OR “sterile woman” in the topic field. The retrieved records were downloaded in plain text and BibTeX formats. The downloaded datasets were imported into the R package to remove the duplicates and perform the bibliometric analysis and science mapping.; ; ; Results; A total of 9288 articles were included in the final analysis. These articles were written by 39,453 authors and were published in 1898 journals between 1939 and 2024. The international co-authorship was 13.34%, whereas the annual growth rate was 8.01%. The most frequently published year was 2024 (n = 698). The top leading journal was “Fertility and Sterility” (n = 802), whereas the most contributing author was Wang Y (n = 65). The most frequently appeared author keywords other than search terms were endometriosis, in vitro fertilization, pregnancy, polycystic ovary syndrome, endometrium, and laparoscopy. The top leading institutions were Tehran University of Medical Sciences, Fudan University, and Shandong University, whereas Yale University, the University of California San Francisco, and Fudan University had the highest betweenness centrality score. China was the leading country in terms of single corresponding author countries, whereas the United States of America (USA) was the most cited country. Moreover, China had the strongest collaboration with the USA.; ; ; Conclusion; The current study provides a comprehensive assessment of female infertility studies over the past eight decades. Recent trend topics during the last decade were infertile women, ovary syndrome, polycystic ovary, in vitro fertilization, and embryo transfer. The well-developed and central themes were in vitro fertilization, randomized control studies, embryo transfer, assisted reproductive technology, pregnancy outcomes, and live birth.; ",30,1,,,Visualization; Infertility; Data science; Gynecology; Medicine; Computer science; Biology; Data mining; Pregnancy; Genetics,,,,,,http://dx.doi.org/10.1186/s43043-025-00222-z,,10.1186/s43043-025-00222-z,,,0,000-780-034-337-569; 001-415-710-557-147; 008-950-369-666-022; 011-718-548-435-475; 021-063-450-646-328; 024-404-331-997-928; 027-401-473-478-790; 028-230-179-078-06X; 029-822-038-335-080; 035-910-538-101-368; 036-240-761-393-101; 043-473-008-851-871; 046-992-864-415-70X; 047-950-346-673-048; 048-959-529-976-495; 061-485-057-708-984; 066-306-321-889-346; 066-332-637-821-910; 078-190-936-827-911; 084-895-486-981-416; 096-058-840-422-746; 104-252-137-267-163; 104-647-773-215-547; 108-161-004-848-337; 127-167-538-710-187; 127-194-383-040-53X; 150-023-754-670-993; 172-588-614-222-036; 195-558-800-222-678,0,true,cc-by,gold -172-258-921-491-840,Charting the managerial and theoretical evolutionary path of AHP using thematic and systematic review: a decadal (2012–2021) study,2022-01-28,2022,journal article,Annals of Operations Research,02545330; 15729338,Springer Science and Business Media LLC,Netherlands,Vijay Pereira; Umesh Bamel,,326,2,635,651,Analytic hierarchy process; Scopus; Multiple-criteria decision analysis; Computer science; Thematic map; Operations research; Management science; Data science; Key (lock); Hierarchy; Knowledge management; Mathematics; Political science; Engineering; Geography; Law; Cartography; MEDLINE; Computer security,,,,,,http://dx.doi.org/10.1007/s10479-022-04540-7,,10.1007/s10479-022-04540-7,,,0,000-209-413-168-336; 006-190-345-716-88X; 006-229-877-506-23X; 006-599-719-621-257; 006-789-871-972-93X; 006-929-857-865-435; 008-511-902-895-946; 013-507-404-965-47X; 014-816-816-491-114; 015-031-962-053-469; 016-119-771-531-408; 016-339-446-520-179; 016-457-789-205-792; 017-012-768-987-451; 017-750-600-412-958; 018-301-055-380-665; 018-458-010-551-294; 019-120-063-489-701; 020-953-174-063-967; 025-299-998-676-14X; 025-653-498-641-556; 025-810-286-381-058; 027-756-814-347-434; 027-957-666-338-00X; 029-766-739-836-263; 030-347-224-968-258; 032-187-636-251-846; 034-713-155-331-474; 034-981-495-361-46X; 037-815-640-424-494; 037-996-759-610-687; 039-758-551-834-971; 040-306-298-495-985; 041-563-133-040-548; 042-478-668-086-876; 043-727-059-728-635; 044-794-893-035-036; 045-968-562-012-159; 046-292-306-147-328; 047-797-185-624-609; 052-150-797-373-584; 052-363-402-512-674; 052-391-493-372-344; 052-438-507-560-713; 053-709-194-097-761; 053-737-635-892-997; 055-929-529-772-86X; 056-677-524-112-924; 057-251-112-897-751; 057-720-474-396-929; 058-062-018-651-310; 061-333-639-971-165; 062-676-794-657-572; 063-014-045-623-686; 064-338-509-039-697; 066-764-881-324-384; 068-285-620-875-342; 071-857-429-994-596; 077-687-937-191-780; 079-888-252-884-377; 080-441-696-142-854; 080-654-308-482-603; 083-457-957-634-95X; 085-300-287-100-525; 088-419-331-202-690; 093-102-543-296-137; 093-106-177-247-543; 097-557-365-949-874; 102-968-056-532-800; 109-670-393-519-626; 111-553-311-144-971; 113-971-287-520-66X; 115-549-975-483-718; 130-462-990-537-712; 133-671-555-323-795; 138-630-596-269-634; 153-203-203-219-001; 154-556-244-657-593; 164-316-479-337-201; 164-716-169-372-274; 165-596-178-769-700; 186-842-017-005-091; 189-739-708-287-167; 195-681-872-367-255,22,false,, -172-266-140-240-002,Trends and research features on greenhouse gas emissions from rice production: review based on bibliometric analysis.,2022-09-14,2022,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Coffi Leonce Geoffroy Sossa; Souleymane Sanogo; Jesse B Naab; Luc O Sintondji,,29,49,73828,73841,Greenhouse gas; Agriculture; Bibliometrics; Path analysis (statistics); Climate change; Greenhouse; Environmental science; China; Global-warming potential; Production (economics); Geography; Computer science; Statistics; Mathematics; Agronomy; Economics; Library science; Ecology; Macroeconomics; Archaeology; Biology,Bibliometric analysis; Climate change; Greenhouse gas; Rice,Agriculture/methods; Bibliometrics; China; Ecosystem; Greenhouse Gases/analysis; Methane/analysis; Nitrous Oxide/analysis; Oryza; Soil,Greenhouse Gases; Soil; Nitrous Oxide; Methane,West African Science Service Centre on Climate Change and Adapted Land Use; Prince Albert II of Monaco Foundation,,http://dx.doi.org/10.1007/s11356-022-22921-0,36103066,10.1007/s11356-022-22921-0,,,0,002-956-995-339-239; 008-331-147-132-583; 009-704-612-661-09X; 011-237-315-108-089; 012-906-079-595-04X; 013-507-404-965-47X; 014-740-405-931-666; 015-820-349-570-435; 017-156-280-318-636; 017-473-732-732-264; 019-840-377-621-440; 022-639-771-611-72X; 023-041-112-650-637; 023-575-972-753-341; 024-314-614-985-282; 026-864-360-292-353; 029-883-007-257-496; 031-780-288-351-12X; 034-337-611-848-201; 034-905-955-850-199; 036-588-490-297-181; 037-252-305-121-449; 037-591-417-191-747; 038-945-446-476-567; 044-808-566-509-681; 045-422-273-148-899; 046-358-044-476-955; 046-457-900-689-069; 047-029-041-692-870; 048-446-908-175-408; 048-702-816-848-687; 049-091-446-347-012; 051-616-568-001-475; 056-293-467-320-07X; 056-600-297-840-095; 063-530-254-881-711; 070-705-474-267-524; 070-755-255-789-889; 071-878-836-294-733; 078-998-956-547-644; 086-583-548-959-362; 093-485-854-728-698; 096-126-345-447-85X; 097-716-991-915-888; 101-775-859-635-160; 106-845-448-387-935; 115-302-490-415-587; 118-026-685-634-748; 138-615-729-232-582; 138-848-071-108-055; 141-986-867-660-05X; 148-475-098-195-156; 151-123-560-272-449; 158-021-928-739-199; 161-658-553-396-738; 168-677-487-797-661; 180-710-344-680-729,7,false,, -172-328-840-351-02X,Circular Economy in the Oil and Gas Industry: A Data-Driven Bibliometric Analysis,2025-05-06,2025,journal article,Circular Economy and Sustainability,2730597x; 27305988,Springer Science and Business Media LLC,,Aishat Adebonike Adedayo-Ojo; Muhammad Kashif Shad; Wai Ching Poon,,,,,,Petroleum industry; Fossil fuel; Economics; Economy; Circular economy; Petroleum engineering; Business; Environmental science; Engineering; Waste management; Environmental engineering; Ecology; Biology,,,,,,http://dx.doi.org/10.1007/s43615-025-00579-3,,10.1007/s43615-025-00579-3,,,0,001-022-359-587-367; 003-986-353-043-480; 004-168-670-248-318; 006-207-822-645-817; 006-974-896-638-57X; 007-981-724-110-48X; 008-464-787-595-948; 008-573-399-183-477; 010-815-205-269-370; 013-507-404-965-47X; 016-985-595-998-543; 017-750-600-412-958; 018-206-129-324-813; 020-232-696-554-958; 021-197-254-455-886; 021-561-556-434-237; 023-125-289-831-933; 023-500-052-180-038; 024-164-016-066-840; 025-167-635-140-050; 025-368-944-252-719; 026-430-385-572-505; 026-980-152-189-309; 026-999-735-409-131; 027-249-322-278-018; 027-361-510-759-169; 027-416-639-788-732; 027-694-401-286-580; 029-566-443-781-113; 030-104-247-459-10X; 030-225-438-863-392; 030-948-742-509-012; 034-033-771-375-551; 035-265-948-173-242; 036-781-074-494-519; 037-424-360-931-282; 038-177-325-027-811; 039-949-667-234-945; 042-228-490-689-212; 042-397-081-731-317; 043-483-395-308-164; 045-422-273-148-899; 045-797-416-772-535; 046-992-864-415-70X; 048-801-932-837-751; 049-378-895-408-480; 053-261-897-039-207; 056-947-172-452-876; 061-208-561-681-850; 065-010-405-236-060; 065-152-353-691-654; 065-549-451-901-681; 066-157-822-409-471; 068-905-827-331-785; 069-568-717-641-59X; 069-800-538-514-636; 070-760-145-451-445; 072-268-539-936-857; 073-872-897-544-762; 075-361-683-580-758; 075-733-413-325-903; 078-152-234-894-67X; 080-041-472-577-936; 082-879-360-854-750; 083-361-123-214-848; 084-179-964-986-055; 084-653-463-108-022; 086-516-013-896-537; 086-939-677-862-326; 088-427-145-755-953; 088-658-937-502-303; 088-894-642-635-111; 089-049-047-360-318; 091-034-981-535-789; 092-972-444-034-396; 092-992-397-737-387; 094-701-858-470-188; 095-570-923-799-203; 096-032-845-178-249; 097-241-531-390-009; 097-388-787-090-41X; 097-701-363-694-71X; 098-247-673-915-038; 098-377-939-800-955; 100-424-015-384-92X; 101-912-825-668-042; 102-881-327-998-900; 102-938-015-893-370; 104-587-443-098-710; 105-816-239-777-647; 107-693-803-390-490; 107-899-347-331-991; 108-397-798-942-093; 109-245-282-914-829; 111-606-487-211-599; 114-822-838-011-042; 118-393-650-963-36X; 119-853-262-475-939; 119-866-591-974-483; 122-827-252-276-011; 122-948-283-306-851; 125-166-512-867-541; 125-803-081-002-827; 125-954-351-593-259; 125-976-912-203-992; 126-739-265-441-237; 130-514-085-170-81X; 136-792-379-153-925; 137-915-834-689-865; 137-971-856-795-868; 138-190-047-995-944; 138-262-467-223-713; 143-211-966-388-61X; 143-693-604-655-906; 145-614-431-247-756; 146-522-325-280-323; 147-859-894-802-734; 148-770-750-765-335; 151-542-869-689-687; 151-857-624-612-709; 153-601-556-153-742; 154-964-851-515-987; 155-483-615-155-069; 157-442-773-168-174; 160-124-499-390-614; 163-592-229-304-09X; 165-136-313-866-478; 165-387-754-595-454; 168-505-053-986-691; 168-671-152-888-492; 169-122-339-962-52X; 174-402-923-264-824; 176-661-395-138-128; 177-414-125-624-239; 179-326-625-020-063; 179-606-411-791-563; 179-841-564-689-009; 180-125-251-721-037; 181-772-926-776-747; 181-846-836-758-747; 182-197-995-000-350; 184-437-615-316-234; 194-451-576-039-783; 197-815-980-724-778; 199-054-289-070-051,0,false,, -172-650-700-562-576,Scientific Mapping of Chatbot Literature: A Bibliometric Analysis,2024-04-01,2024,journal article,"International Journal of Mathematical, Engineering and Management Sciences",24557749,Ram Arti Publishers,,Manju Tanwar; Harsh V. Verma,"The use of chatbots for customer service has gained momentum in recent years. Increasing evidence has shown that chatbots can transform the customer service landscape. Nevertheless, this topic currently lacks adequate bibliometric and visualization research. In order to review and summarise the research on chatbots, the study employs a bibliometric analysis approach to gain a comprehensive understanding of chatbots. The study uses bibliometric analysis of 798 documents sourced from the Scopus database from 2001 to 2022. The combination of biblioshiny (web interface application of Bibliometrix) and VOS viewer software was used to visualize the analysis. The study's findings reveal three prominent areas in the current research: antecedents of the adoption of chatbots, application of chatbots and behavioural & relational outcomes of the application of chatbots. The future directions and implications have been discussed in the study's conclusion.",9,2,323,340,Chatbot; Visualization; Scopus; Computer science; Data science; Service (business); Web of science; World Wide Web; Data mining; MEDLINE; Political science; Economy; Law; Economics,,,,,,http://dx.doi.org/10.33889/ijmems.2024.9.2.017,,10.33889/ijmems.2024.9.2.017,,,0,003-118-998-063-278; 003-613-850-211-092; 006-577-988-416-318; 006-731-116-013-936; 008-172-093-666-743; 009-441-049-298-006; 011-195-430-027-417; 012-358-218-196-66X; 014-370-642-060-096; 014-413-347-535-842; 014-795-824-390-866; 017-618-171-729-878; 019-061-755-635-493; 021-224-959-455-81X; 021-596-968-585-322; 024-800-443-292-177; 025-488-956-273-185; 031-824-009-360-923; 033-451-056-986-404; 033-826-575-023-317; 038-542-401-155-229; 038-665-948-694-648; 038-925-283-945-155; 039-687-269-147-304; 042-427-895-200-114; 044-776-532-451-668; 046-992-864-415-70X; 049-463-493-827-566; 051-011-707-462-588; 052-245-171-683-03X; 053-434-144-774-904; 053-499-617-825-140; 055-594-760-386-281; 057-464-105-634-557; 058-237-210-680-260; 059-805-994-516-643; 060-623-518-166-185; 060-633-055-700-538; 062-971-577-059-13X; 063-369-905-442-619; 063-630-981-711-864; 064-495-185-205-255; 066-641-392-507-323; 068-255-013-275-268; 068-808-800-036-327; 074-601-462-746-690; 074-829-469-130-718; 075-209-201-506-98X; 076-418-919-113-971; 078-038-918-723-83X; 084-720-591-769-228; 084-943-368-720-075; 085-250-227-675-391; 096-143-596-574-241; 103-211-405-753-065; 104-862-779-392-300; 108-444-682-261-631; 110-523-122-951-914; 119-146-042-099-078; 119-275-549-696-155; 128-141-164-469-966; 129-449-629-185-427; 130-103-767-490-531; 138-440-879-598-406; 139-728-534-969-805; 140-257-398-405-251; 150-887-963-505-239; 152-620-372-579-236; 153-202-706-200-690; 153-982-639-705-321; 158-380-352-322-052; 159-549-280-195-935; 163-864-824-279-286; 166-812-736-211-921; 171-518-933-195-178; 194-870-472-784-283,2,true,cc-by,gold -173-404-101-874-693,La ética en la neurociencia aplicada a alimentos: Un análisis bibliométrico,2023-07-05,2023,journal article,Manglar,18167667; 24141046,Universidad Nacional de Tumbes,,Delia Izaguirre Torres; Maria Pilar Ruiz Santillan,"Technological advances in the field of neuroscience are enabling new investigations of consumer decision-making processes in today's world settings. The purpose of this study was to analyze the evolution, characteristics, and relationships of research in neuroscience applied to food, but with an ethical approach. A bibliometric analysis was carried out with scientific information taken from the Scopus database, years 2005 to 2023, search words Ethics, neuroscience and food and using VosViewer and Bibliometrix. It was found that the United Kingdom is the most productive country with emphasis on 4 areas: animal welfare, reward, treatment, and deep brain stimulation, followed by the United States, which concentrates its research in neuroscience and health education. The countries that have related their research to ethics are France and the United States. With the VosViewer co-occurrence analysis, two clusters are visualized, one of neuroscience studies in humans, and another of neuroscience studies in non-humans or animals. In both ethics as an important aspect of analysis. With Bibliometrix, five clusters are visualized: neuroscience, health education, animal welfare, marketing-ethics, and Alzheimer-brain-neuroethics. Animal welfare is a basic topic, neuroscience (as pure science) a topic in decline, health education and studies in Alzheimer-brain-neuroethics are niche topics, and motor topics are associated with marketing and ethics. With the word cloud technique, it is observed that from 1996 to 2011 neuroscience studies in humans stand out; between 2012 and 2017 studies on the human brain and ethics; From 2018 to the present, neuroscience studies in humans continue to be in force, appearing as an important topic in animal welfare studies, associated with ethics. The brain-human binomial becomes a relevant issue from 2012 to the present. Research in humans and the brain, associated with ethical aspects, is of greater importance as of 2015. In conclusion, studying the brain and animal welfare, associated with ethics, are topics for future research.",20,2,185,191,Neuroethics; Neuroscience; Psychology; Cognitive neuroscience; Social neuroscience; Cognitive science; Political science; Cognition; Social cognition,,,,,https://revistas.untumbes.edu.pe/index.php/manglar/article/download/372/711 https://doi.org/10.57188/manglar.2023.021,http://dx.doi.org/10.57188/manglar.2023.021,,10.57188/manglar.2023.021,,,0,,0,true,cc-by,gold -173-504-571-067-261,Journal of human resources in hospitality and tourism: a bibliometric overview,2022-05-13,2022,journal article,Journal of Human Resources in Hospitality & Tourism,15332845; 15332853,Informa UK Limited,United States,Ranjit Singh; Amit Kumar Singh; Sibi PS,"In the celebration of the 20th anniversary of the Journal of Human Resources in Hospitality & Tourism, this study presents a comprehensive overview of the journal between 2002 and 2020 based on bibliometric analysis to highlight the key trends and dominant topics in the journal. Bibliographic data were extracted from the Scopus and these data were analyzed using ""bibliometrix"" tool, a tool for bibliometrics and scientometrics. The findings show the strong growth of JHRHT over time and a huge diversity of publications are published based on human resources practices and issues from around the world, especially the USA, Australia and Turkey.",21,3,441,462,Scopus; Bibliometrics; Hospitality; Tourism; Scientometrics; Human resources; Diversity (politics); Library science; Data science; Political science; Sociology; Computer science; MEDLINE; Anthropology; Law,,,,,,http://dx.doi.org/10.1080/15332845.2022.2064184,,10.1080/15332845.2022.2064184,,,0,001-174-915-546-834; 001-278-768-624-05X; 004-935-337-445-822; 005-858-010-321-086; 005-898-678-922-275; 006-644-524-693-154; 007-227-559-082-555; 008-681-243-919-044; 010-352-292-366-68X; 010-408-872-396-13X; 011-593-548-969-577; 012-571-188-384-573; 013-507-404-965-47X; 013-524-854-219-241; 013-842-081-437-231; 015-247-893-027-664; 015-284-651-264-336; 015-372-468-115-439; 016-655-706-124-813; 019-014-667-197-890; 019-996-872-294-097; 020-344-631-662-786; 021-698-287-762-108; 022-509-785-910-67X; 022-710-142-577-046; 023-911-262-248-981; 024-460-504-082-969; 025-418-571-249-228; 025-613-778-875-828; 025-855-318-734-145; 026-390-183-299-834; 026-582-800-045-650; 027-191-955-223-739; 029-116-322-768-31X; 029-740-004-244-894; 030-644-175-051-806; 031-340-308-099-496; 032-318-770-533-876; 032-483-300-065-800; 033-171-354-077-456; 033-307-786-945-43X; 037-691-582-692-746; 037-815-640-424-494; 041-381-321-549-31X; 041-539-918-096-269; 045-149-495-504-129; 045-450-455-884-211; 047-510-743-617-358; 048-770-776-128-056; 053-911-900-953-561; 054-714-582-290-216; 064-715-311-615-864; 065-976-661-343-979; 066-849-661-222-258; 067-711-057-302-416; 067-929-257-899-036; 071-756-045-198-301; 072-432-007-405-053; 072-813-199-606-608; 074-624-932-314-481; 075-882-203-385-851; 076-118-915-808-018; 077-626-969-557-709; 077-930-616-453-628; 080-207-724-510-461; 080-342-840-938-82X; 083-296-449-634-342; 084-943-085-450-677; 088-422-990-931-456; 090-474-173-777-15X; 098-637-643-942-522; 100-121-811-040-898; 107-814-524-142-062; 111-019-419-316-544; 112-911-165-843-531; 120-974-286-046-262; 121-177-925-533-900; 121-994-883-510-873; 122-244-035-302-266; 124-880-745-362-773; 125-311-949-520-557; 126-954-383-350-522; 133-498-596-986-097; 147-015-281-325-971; 161-841-133-468-251; 164-778-740-921-61X; 176-043-742-812-60X; 179-895-816-255-420,5,false,, -173-900-599-988-083,ICT Implementations: Typology of Using Digital Platforms for Efficient Business Performance in Microfinance Institutions a Bibliometrix Perspective,2024-10-03,2024,conference proceedings article,2024 12th International Conference on Cyber and IT Service Management (CITSM),,IEEE,,Dhiyan Septa Wihara; Hafid Kholidi Hadi; Ratih Amelia; Muhammad Fachmi,,,,1,6,Microfinance; Typology; Implementation; Perspective (graphical); Information and Communications Technology; Business; Computer science; Knowledge management; World Wide Web; Sociology; Software engineering; Economics; Economic growth; Artificial intelligence; Anthropology,,,,,,http://dx.doi.org/10.1109/citsm64103.2024.10775433,,10.1109/citsm64103.2024.10775433,,,0,,0,false,, -174-064-718-304-859,A bibliometrics analysis based on the application of artificial intelligence in the field of radiotherapy from 2003 to 2023.,2024-11-11,2024,journal article,"Radiation oncology (London, England)",1748717x,Springer Science and Business Media LLC,United Kingdom,Minghe Lv; Yue Feng; Su Zeng; Yang Zhang; Wenhao Shen; Wenhui Guan; Xiangyu E; Hongwei Zeng; Ruping Zhao; Jingping Yu,"Recent research has demonstrated that the use of artificial intelligence (AI) in radiotherapy (RT) has significantly streamlined the process for physicians to treat patients with tumors; however, bibliometric studies examining the correlation between AI and RT are not available. Providing a thorough overview of the knowledge structure and research hotspots between AI and RT was the main goal of the current study.; A search was conducted on the Web of Science Core Collection (WoSCC) database for publications pertaining to AI and RT between 2003 and 2023. VOSviewers, CiteSpace, and the R program ""bibliometrix"" were used to do the bibliometric analysis.; The analysis comprised 615 publications from 64 countries, with USA and China leading the pack. Since 2017, there have been more and more publications about RT and AI every year. The research center that made the biggest contribution to this topic was Maastricht University. The most articles published journal in this field was Frontiers in Oncology, while Medical Physics received the greatest number of citations. Dekker Andre is the author with the greatest number of published articles, while Philippe Lambin was the most often co-cited author. In the newly identified research hotspots, ""autocontouring algorithm"", ""deep learning"", and ""machine learning"" stand out as the main terms.; In fact, our bibliometric analysis offers insightful information on current research directions and advancements pertaining to the use of AI in RT. For academics looking to understand the connection between AI and RT, this study is a great resource because it highlights current research frontiers and hot trends.; © 2024. The Author(s).",19,1,157,,Medicine; Bibliometrics; Radiation therapy; Field (mathematics); Medical physics; Library science; Internal medicine; Mathematics; Computer science; Pure mathematics,Artificial intelligence; Bibliometrics; Radiotherapy,Bibliometrics; Humans; Artificial Intelligence; Radiotherapy/methods; Neoplasms/radiotherapy; Radiation Oncology/methods,,Science and technology development project of Shanghai University of Traditional Chinese Medicine (23KFL105); the Integrated Chinese and western medicine project of Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine (SGZXY-202201); the Shanghai Health Commission (202340160),,http://dx.doi.org/10.1186/s13014-024-02551-1,39529129,10.1186/s13014-024-02551-1,,PMC11552138,0,000-269-899-960-810; 001-162-437-674-007; 002-052-422-936-00X; 004-631-607-805-654; 007-252-689-690-617; 007-500-155-247-91X; 011-085-359-238-563; 015-282-479-135-807; 019-167-842-619-761; 021-537-046-179-539; 022-607-112-877-974; 033-763-591-669-454; 035-731-410-128-904; 038-773-494-898-395; 038-875-171-796-578; 042-726-570-225-196; 046-767-401-268-167; 053-125-970-037-181; 057-608-777-240-622; 059-149-073-001-124; 062-109-541-861-398; 064-400-499-357-900; 074-495-478-748-598; 080-379-901-297-886; 080-977-108-232-315; 089-409-938-765-016; 092-429-030-442-934; 098-457-050-736-207; 105-142-479-733-653; 139-335-986-863-860; 150-549-430-851-540; 167-131-435-704-717; 169-239-902-574-681; 181-902-568-708-973; 185-415-573-286-784,1,true,"CC BY, CC0",gold -174-205-135-690-088,Trends in endemic plant research under climate change scenarios: a bibliometric analysis (1990–2025),2025-05-24,2025,journal article,Theoretical and Applied Climatology,0177798x; 14344483,Springer Science and Business Media LLC,Germany,Yanet Moredia Rosete; Zayner Edin Rodríguez Flores; Yolanda Leticia Fernández Pavía,,156,6,,,Climate change; Environmental science; Climatology; Trend analysis; Geography; Physical geography; Statistics; Geology; Mathematics; Oceanography,,,,Consejo Mexiquense de Ciencia y Tecnología,,http://dx.doi.org/10.1007/s00704-025-05553-5,,10.1007/s00704-025-05553-5,,,0,000-140-988-248-625; 000-327-385-252-916; 002-052-422-936-00X; 011-531-085-677-151; 013-507-404-965-47X; 014-061-313-669-918; 016-693-952-631-850; 016-771-491-128-769; 019-148-019-556-115; 020-856-430-857-818; 023-614-018-504-807; 024-194-174-576-296; 029-766-275-480-974; 034-548-585-569-70X; 034-669-811-755-131; 034-768-039-318-254; 034-968-507-872-632; 035-081-326-853-407; 035-137-051-319-677; 035-151-330-423-769; 041-103-360-405-191; 041-910-360-555-238; 043-537-093-027-149; 048-186-942-721-726; 048-722-855-002-762; 049-147-902-085-272; 052-744-008-201-957; 058-819-340-780-251; 059-236-275-881-495; 059-712-017-197-038; 060-921-339-449-644; 068-004-189-079-408; 073-351-525-506-497; 075-066-696-074-211; 079-779-080-899-181; 080-519-919-587-525; 082-376-622-785-974; 083-422-344-145-90X; 084-655-182-888-578; 085-509-503-021-74X; 099-665-880-397-753; 101-086-142-990-460; 104-046-963-929-467; 111-268-767-864-536; 113-419-893-760-736; 113-724-279-433-680; 118-914-352-401-589; 126-187-067-881-597; 141-562-203-874-638; 151-428-901-142-78X; 154-302-422-182-27X; 154-862-407-472-186,0,false,, -174-210-641-976-982,Knowledge mapping of research on peri urban areas: a bibliometric analysis,2023-07-29,2023,journal article,GeoJournal,15729893; 03432521,Springer Science and Business Media LLC,Netherlands,Pallavi Tiwari; Preeti Vajpeyi,,88,5,5353,5364,Urbanization; Geography; Context (archaeology); Regional science; Population; Human geography; Environmental planning; Urban planning; Economic geography; Urban agglomeration; Environmental resource management; Economic growth; Civil engineering; Sociology; Environmental science; Engineering; Demography; Archaeology; Economics,,,,,,http://dx.doi.org/10.1007/s10708-023-10915-5,,10.1007/s10708-023-10915-5,,,0,000-254-154-447-21X; 002-532-803-333-416; 008-573-968-365-554; 011-016-014-543-424; 014-472-784-984-582; 014-782-554-817-897; 016-273-581-099-277; 018-075-553-884-062; 021-787-669-223-331; 025-357-164-920-743; 037-440-770-520-056; 038-236-526-644-653; 038-255-827-772-003; 049-053-449-487-224; 056-430-594-895-501; 066-439-610-433-096; 069-694-266-917-573; 070-966-660-443-662; 071-345-990-707-362; 082-447-194-108-381; 088-336-415-501-694; 094-722-359-332-541; 101-579-669-775-367; 109-478-320-158-962; 127-330-174-104-203; 169-278-455-063-231; 170-879-143-260-657; 174-576-725-884-811; 184-371-939-065-583; 196-784-908-492-938,5,false,, -174-475-974-890-443,"Structure, trend and prospect of operational research: a scientific analysis for publications from 1952 to 2020 included in Web of Science database",2022-01-04,2022,journal article,Fuzzy Optimization and Decision Making,15684539; 15732908,Springer Science and Business Media LLC,Netherlands,Xinxin Wang; Zeshui Xu; Yong Qin,,21,4,649,672,Timeline; Web of science; Trend analysis; Field (mathematics); Bibliometrics; Computer science; Data science; Database; Library science; Political science; Statistics; MEDLINE; Mathematics; Machine learning; Pure mathematics; Law,,,,Innovative Research Group Project of the National Natural Science Foundation of China; Innovative Research Group Project of the National Natural Science Foundation of China,,http://dx.doi.org/10.1007/s10700-021-09380-x,,10.1007/s10700-021-09380-x,,,0,001-719-026-803-199; 002-988-557-513-715; 006-564-247-336-203; 007-227-404-263-394; 007-683-181-791-18X; 013-238-094-033-681; 013-375-400-569-574; 013-507-404-965-47X; 013-732-703-361-327; 014-408-229-090-129; 017-146-468-093-265; 033-165-598-856-017; 038-984-952-629-230; 039-025-670-467-694; 040-637-567-005-013; 046-547-268-714-476; 047-134-478-431-993; 047-381-298-575-664; 049-875-730-889-092; 060-661-239-491-097; 062-162-022-871-394; 064-400-499-357-900; 064-482-912-103-288; 071-958-550-139-56X; 073-520-648-542-951; 082-113-490-224-491; 084-167-367-903-305; 102-637-372-638-002; 106-792-387-463-976; 130-602-202-936-694; 137-575-360-738-267; 153-949-238-252-718; 189-352-970-391-692,11,false,, -174-605-351-310-142,Bibliometric insights into the application of natural deep eutectic solvents in extracting bioactive compounds from fruit wastes,2024-07-01,2024,journal article,International Journal of Environmental Science and Technology,17351472; 17352630,Springer Science and Business Media LLC,"Iran, Islamic Republic of",N. D. de Lima; B. R. S. M. Wanderley; M. J. O. Almeida; C. B. Fritzen Freire; R. D. M. C. Amboni,,22,3,1905,1920,Eutectic system; Natural (archaeology); Ecotoxicology; Environmental science; Chemistry; Biochemical engineering; Waste management; Environmental chemistry; Pulp and paper industry; Engineering; Organic chemistry; Geography; Archaeology; Alloy,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Conselho Nacional de Desenvolvimento Científico e Tecnológico,,http://dx.doi.org/10.1007/s13762-024-05855-7,,10.1007/s13762-024-05855-7,,,0,000-881-328-558-837; 001-009-744-062-86X; 001-057-929-097-870; 001-586-992-730-214; 005-028-885-323-92X; 006-626-384-329-06X; 006-932-801-499-154; 009-466-427-311-089; 009-717-150-136-815; 013-969-637-687-120; 014-230-028-191-155; 014-241-850-099-349; 014-564-864-112-803; 018-180-932-330-97X; 019-120-086-039-519; 020-338-882-630-024; 021-368-917-985-540; 021-534-793-352-135; 026-685-403-099-542; 026-705-264-111-489; 027-570-815-362-593; 028-324-823-110-559; 028-365-163-067-997; 030-398-301-012-39X; 030-415-288-514-572; 031-504-110-865-886; 032-780-169-907-849; 033-223-785-383-481; 034-169-329-899-101; 036-864-155-832-691; 045-466-350-618-976; 045-958-778-493-132; 046-603-273-727-670; 046-639-103-275-40X; 049-731-182-109-450; 049-813-669-362-115; 052-414-431-835-234; 055-733-200-400-492; 059-370-611-088-486; 062-311-900-055-005; 065-834-961-617-456; 067-927-059-771-649; 069-062-959-831-97X; 069-071-282-418-458; 069-763-232-284-858; 070-827-037-215-406; 072-093-776-057-766; 072-302-813-512-093; 077-154-177-614-75X; 079-946-710-406-464; 082-529-924-039-429; 089-370-745-463-753; 093-154-482-862-282; 103-264-897-786-830; 107-212-977-106-146; 107-665-209-553-009; 108-776-631-060-54X; 109-384-179-422-850; 109-952-553-040-709; 112-888-238-866-804; 115-140-842-935-326; 116-423-011-346-332; 117-021-316-525-520; 123-235-486-403-148; 124-035-228-602-97X; 124-303-588-371-720; 128-462-742-277-550; 130-134-578-881-13X; 131-186-960-029-029; 132-043-532-406-64X; 133-310-380-004-229; 134-212-986-977-073; 137-909-607-714-812; 140-494-458-836-635; 143-221-361-477-504; 143-943-460-875-596; 145-881-610-998-834; 146-413-739-854-785; 151-035-556-785-268; 156-539-063-993-705; 158-768-784-308-909; 162-570-153-921-169; 170-925-813-047-682; 172-241-777-248-115; 173-448-333-865-192; 176-526-328-440-86X; 178-821-837-451-094; 189-011-278-511-576; 194-295-289-841-19X; 195-611-855-697-451,2,false,, -174-622-513-556-896,COVID-19 and teachers' digital competencies: a comprehensive bibliometric and topic modeling analysis,2024-12-27,2024,journal article,Humanities and Social Sciences Communications,26629992,Springer Science and Business Media LLC,,İbrahim Gökdaş; Ömer Cem Karacaoğlu; Abdulkadir Özkaya,"With the escalating global emphasis on information and communication technologies, the imperative of bolstering and enhancing teachers' digital proficiencies comes to the forefront. Against this backdrop, this study endeavors to discern the prevailing trends and principal themes in the scholarly landscape by conducting a comprehensive analysis of research pertaining to teachers' digital competences. The methodological framework of the inquiry encompasses two pivotal phases: bibliometric analysis and topic modeling analysis focusing on teachers' digital competencies. Drawing upon a corpus of 3352 documents spanning the years 1994 to 2024 sourced from eminent databases such as Web of Science and Scopus, these analyses serve as the cornerstone of the investigation. By subjecting the texts to descriptive content analysis and topic modeling analysis, the study seeks to pinpoint the focal points and unveil semantic patterns inherent within the literature. The primary revelations of the inquiry underscore the burgeoning interest in studies pertaining to teachers' digital competences, particularly spurred by exigent circumstances such as the COVID-19 pandemic. Bibliometric analyses illuminate a marked quantitative and qualitative upsurge in research output in this domain, underscoring the pivotal role of teachers' digital proficiencies in the realm of education. The thematic contours of the research encapsulate digital skills cultivation, teacher training, the assimilation of digital technologies into pedagogical strategies, and the role of technology in times of crises such as pandemics. The findings posit that teachers' digital competences harbor the potential to augment student attainment and advocate for continued scholarly endeavors in this domain. It is advocated that forthcoming studies adopt diverse frameworks to elucidate the nexus between curricula and digital competences, thereby fostering the development of more efficacious strategies.",11,1,,,Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Computer science; Data science; Medicine; Virology; Internal medicine; Disease; Outbreak; Infectious disease (medical specialty),,,,,,http://dx.doi.org/10.1057/s41599-024-04335-0,,10.1057/s41599-024-04335-0,,,0,000-667-231-896-402; 004-051-351-248-32X; 004-116-025-943-559; 006-225-734-801-006; 008-092-272-768-77X; 009-286-240-384-618; 009-860-878-085-063; 010-959-761-331-318; 011-517-724-688-500; 014-701-830-171-774; 017-223-012-396-918; 018-249-336-636-924; 019-042-700-105-600; 020-707-238-419-085; 023-426-752-332-431; 023-885-170-368-525; 025-790-127-979-84X; 025-798-207-013-97X; 028-535-760-580-712; 031-272-181-919-116; 031-794-137-389-398; 039-813-073-584-355; 041-560-466-587-10X; 046-477-530-142-469; 046-946-007-619-508; 049-391-379-302-694; 050-406-469-952-732; 054-263-717-119-214; 054-854-446-043-813; 060-101-362-959-403; 062-845-011-555-225; 067-545-623-363-707; 069-085-471-239-632; 072-834-364-426-073; 074-800-397-515-571; 079-667-838-218-751; 087-935-660-550-332; 091-501-730-331-087; 096-213-068-723-97X; 101-352-069-802-556; 104-489-077-105-239; 104-736-706-266-840; 110-160-423-588-864; 115-108-625-841-614; 120-229-008-066-319; 120-465-778-812-407; 122-648-507-859-400; 123-186-028-612-059; 125-420-212-519-87X; 125-536-656-535-146; 129-327-004-714-880; 130-562-497-139-428; 138-030-029-108-819; 138-186-154-308-810; 138-321-758-966-557; 139-648-496-824-436; 140-802-005-878-404; 146-177-547-251-857; 146-424-407-870-766; 150-323-504-598-073; 154-909-986-335-818; 166-985-211-327-679; 169-739-684-113-801; 182-527-448-952-431; 192-232-464-814-519,3,true,cc-by,gold -174-648-220-908-072,How green is Green IT? A multidisciplinary bibliometric study and research agenda,,2024,journal article,Procedia Computer Science,18770509,Elsevier BV,,Cameron Guthrie,"Scholarly interest in Green IT has been rapidly growing over the past 15 years in a wide variety of disciplines including computer science, information systems, sustainability, production management and engineering. This is not surprising given the growing environmental impacts of information and communication technologies. This article presents a bibliometric analysis of academic literature across 1862 sources to improve our understanding of the evolution and current state of this multidisciplinary field. The corpus includes 4067 published journal and conference papers identified using the Scopus database. A descriptive performance analysis of the corpus using Bibliometrix software first allows us to identify the most influential works, authors, sources, institutions, and countries in the field. Examination of its conceptual structure reveals that most work has focused on the design and use phases of ICTs and neglected the manufacturing and end-of-life phases. Further insights are provided and opportunities for future research are identified.",239,,701,709,Multidisciplinary approach; Scopus; Variety (cybernetics); Computer science; Sustainability; Field (mathematics); Bibliometrics; Data science; Work (physics); Green computing; Engineering ethics; Management science; Knowledge management; Library science; Sociology; Social science; Political science; Artificial intelligence; Mechanical engineering; Ecology; MEDLINE; Pure mathematics; Law; Biology; Engineering; Cloud computing; Mathematics; Economics; Operating system,,,,,,http://dx.doi.org/10.1016/j.procs.2024.06.226,,10.1016/j.procs.2024.06.226,,,0,000-620-668-708-795; 001-498-869-192-625; 013-124-029-603-777; 013-507-404-965-47X; 018-523-654-839-152; 024-383-705-083-339; 035-492-180-138-967; 047-637-858-772-508; 062-530-377-496-091; 074-279-238-515-510; 082-564-675-836-323; 088-833-648-905-726; 096-887-073-024-939; 127-356-760-504-467; 132-535-331-669-719,2,true,,gold -174-679-552-014-771,Determinants of rural tourism development: A bibliometric review,,2024,conference proceedings article,"Employment, Education and Entrepreneurship 2024 - zbornik radova",,Faculty of Business Economics and Entrepreneurship,,Sergii Iaromenko; Łukasz Kryszak,"This study aims to identify the current hotspots and research directions in rural tourism development with a focus on its influencing factors, access to resources, the role of public goods, and spatial aspects of rural tourism activities. We collected 933 journal articles from the Scopus database and analyzed them using VOSviewer and Bibliometrix tools. The results indicate an increasing trend for research in rural tourism sustainability, community-based rural tourism, and constraints in rural tourism value chains. This study identified factors that affect rural tourism, and the role of public goods and the infrastructure in tourism development. The perspective research directions are the systematization of determinants from a demand-supply perspective, to specify the role of infrastructure for access to rural tourism destinations, spatial dependencies and their impact on tourism-policy decisions.",,,362,374,Tourism; Regional science; Computer science; Rural tourism; Data science; Geography; Tourism geography; Archaeology,,,,,,http://dx.doi.org/10.5937/eee24034i,,10.5937/eee24034i,,,0,001-561-287-888-63X; 001-567-170-627-855; 005-089-902-564-83X; 005-121-718-277-811; 007-369-623-927-561; 012-537-214-942-702; 013-507-404-965-47X; 013-524-854-219-241; 014-094-397-110-206; 014-279-523-369-368; 015-924-338-820-685; 017-189-230-394-607; 017-991-344-133-489; 020-171-094-589-049; 023-466-076-577-068; 024-062-014-345-355; 024-395-683-057-110; 025-413-719-898-003; 027-958-161-199-66X; 030-348-220-542-588; 030-424-969-825-40X; 035-009-909-916-696; 037-054-339-204-261; 039-875-397-849-499; 039-946-307-317-110; 040-638-064-074-29X; 040-699-454-103-569; 041-213-118-008-603; 041-810-255-080-199; 042-697-073-813-173; 046-992-864-415-70X; 046-995-763-667-75X; 049-695-577-449-614; 050-854-065-100-874; 051-883-764-185-60X; 052-793-172-356-855; 053-888-774-273-780; 054-002-796-269-556; 056-345-200-523-523; 056-397-095-278-849; 057-332-424-635-579; 061-696-630-095-544; 063-782-925-857-917; 064-207-305-233-850; 064-312-874-998-460; 064-671-738-352-985; 066-234-161-483-557; 068-681-967-358-517; 073-562-216-893-921; 074-617-448-975-960; 077-283-230-823-667; 079-092-995-834-617; 081-473-868-076-607; 082-403-362-047-510; 084-573-523-825-454; 086-055-364-840-296; 087-224-652-273-135; 090-939-063-795-418; 091-139-764-271-669; 092-401-602-322-192; 092-905-251-764-907; 094-922-391-968-618; 094-995-851-183-916; 095-105-291-819-064; 095-927-135-418-43X; 104-733-572-386-164; 107-103-561-909-049; 110-678-564-242-708; 112-206-101-930-608; 113-760-509-602-573; 114-229-711-030-089; 115-511-682-337-764; 123-152-926-866-725; 126-465-914-872-315; 126-813-915-914-503; 129-508-813-677-218; 133-593-824-521-36X; 135-611-105-757-199; 140-524-618-698-943; 144-053-550-640-792; 144-896-497-668-088; 153-607-121-198-80X; 166-747-881-253-126; 167-864-079-294-974; 175-859-455-833-892; 181-530-326-525-459; 186-088-463-963-415; 190-755-865-313-467; 196-365-850-717-287; 196-965-307-186-372,0,false,, -174-735-526-282-629,Planning and resource allocation models in research‐intensive universities: budget allocation and the search for excellence,2025-04-04,2025,journal article,Humanities and Social Sciences Communications,26629992,Springer Science and Business Media LLC,,Luciane Graziele Pereira Ferrero; Sergio Luiz Monteiro Salles-Filho,"Research universities worldwide operate in an environment of constant change, with multiple missions, highlighting the importance of efficient and effective management of their financial resources. One of the significant concerns is the allocation of resources in budget programmes that promote institutional objectives of strategic planning related to academic excellence and socioeconomic relevance. In this context, research university managers seek to employ strategies to address this issue. The research question addressed in this article refers to whether institutional planning, linked to the allocation of resources in academic units, may contribute to promoting excellence and relevance inside academic units. This article provides an update on how research universities worldwide have approached this issue and presents a case study using data from one of the most prominent research universities in Latin America. The article examines budget allocation models and indicators with a specific emphasis on institutional strategies within the Global South. Using mathematical analysis, we propose a novel model that demonstrates the relationship between institutional strategic objectives in budget programmes and the results of each academic unit, with flexibility while preserving their particularities in terms of missions and areas of knowledge. This model allows the university and the academic units themselves to prioritise their indicators. The university can then use its budget to encourage units to move in a direction that is in the interest of the university as a whole and the units themselves.",12,1,,,Excellence; Resource allocation; Business; Resource (disambiguation); Environmental economics; Operations research; Management science; Computer science; Economics; Political science; Engineering; Management; Computer network; Law,,,,,,http://dx.doi.org/10.1057/s41599-025-04778-z,,10.1057/s41599-025-04778-z,,,0,001-951-647-065-180; 002-539-370-032-23X; 004-305-357-791-611; 006-258-993-880-942; 006-590-768-518-036; 007-686-932-781-817; 012-397-663-739-804; 013-507-404-965-47X; 013-964-107-618-600; 014-638-401-528-510; 017-441-487-516-624; 020-080-046-935-409; 025-063-433-522-548; 025-961-223-920-446; 026-793-890-342-949; 027-940-382-972-331; 031-387-341-143-004; 033-945-274-221-418; 039-736-867-726-419; 040-802-878-656-91X; 050-483-224-985-201; 054-326-416-927-272; 055-876-393-611-971; 056-663-638-666-944; 062-531-732-594-468; 066-651-251-410-295; 068-694-604-826-716; 069-462-641-030-278; 069-993-224-503-09X; 075-244-704-271-899; 075-555-846-878-969; 080-835-999-781-655; 081-532-972-369-677; 082-005-486-001-561; 082-906-367-637-469; 085-991-857-994-686; 086-797-003-398-239; 090-211-710-415-687; 097-057-990-480-599; 097-292-439-839-491; 102-273-005-402-810; 104-917-471-669-858; 109-042-206-729-242; 122-022-464-666-486; 123-777-319-970-408; 125-456-861-150-456; 125-863-912-698-824; 128-972-931-623-416; 131-444-336-155-370; 132-337-908-581-029; 150-081-447-404-340; 154-090-918-423-100; 165-447-911-101-684; 169-037-955-775-14X; 196-388-879-308-69X; 197-056-262-173-057; 198-236-277-261-361,0,true,cc-by,gold -175-267-093-696-704,Textile and machine learning: A Bibliometric analysis,2022-07-26,2022,journal article,INNOVATION & DEVELOPMENT IN ENGINEERING AND APPLIED SCIENCES,26005573,Universidad Tecnica del Norte,,Ana Umaquinga; Marco Naranjo Toro; OMAR GODOY COLLAGUAZO,"Abstract. In the present research, a bibliometric analysis of scientific publications in the area of textile sciences from the area of machine learning is carried out. The search equation identifies as keywords (i) textile and (ii) machine learning from the scopus database, obtaining as initial result 308 publications, being 281 the final publications to be studied from 1991 to 2022. The bibliometric analysis was carried out using bibliometrix and VOS Viewer, showing the growing interest of the scientific community and authors in this area of research.",4,1,,,Scopus; Textile; Bibliometrics; Computer science; Artificial intelligence; Data science; Library science; Geography; Archaeology; Political science; MEDLINE; Law,,,,,http://revistasojs.utn.edu.ec/index.php/ideas/article/download/697/622 https://doi.org/10.53358/ideas.v4i1.697,http://dx.doi.org/10.53358/ideas.v4i1.697,,10.53358/ideas.v4i1.697,,,0,,0,true,,bronze -175-761-578-728-608,ceRNA networks in ischemic stroke: a bibliometric analysis,2025-03-22,2025,journal article,Egyptian Journal of Medical Human Genetics,20902441; 11108630,Springer Science and Business Media LLC,Egypt,Loo Keat Wei; Lyn R. Griffiths; Trygve O. Tollefsbol,"Abstract; ; Background and method; Ischemic stroke, a leading cause of death and disability worldwide, has been increasingly linked to ceRNA networks, which regulate neuronal damage and recovery. Despite growing interest, a comprehensive bibliometric analysis of ceRNA’s role in stroke remains limited. This study examines the research landscape, key trends, and future directions using Bibliometrix R package, VOSviewer, and CiteSpace. Bibliometrix (Biblioshiny) was used to analyze research growth, author productivity, and global collaboration. VOSviewer facilitated network visualization in co-occurrence, co-citation, and bibliographic coupling analyses, while CiteSpace identified emerging trends and key contributors through citation burst analysis and thematic clustering.; ; ; Results; Our analysis revealed a rapid surge in ceRNA-related ischemic stroke research from 2018 to 2024, with China leading in research output and global collaborations. Co-citation analysis identified three major thematic clusters: circRNAs in autophagy, lncRNAs within the ceRNA hypothesis, and the complexity of ceRNA networks in middle cerebral artery occlusion. Bibliographic coupling analysis highlighted five key research domains: lncRNA- and circRNA-mediated ceRNA networks, neurovascular injury, epigenetic regulation, and immune pathogenesis, highlighting their pivotal role in stroke mechanisms and therapeutic strategies. Molecular Medicine Reports ranked as the most influential journal, while Fudan University led institutional contributions. Thematic mapping identified inflammation and biomarkers as emerging research frontiers, suggesting potential novel therapeutic targets.; ; ; Conclusion; This study provides a comprehensive analysis of ceRNA research in ischemic stroke, highlighting key trends, emerging frontiers, and therapeutic potential. The increasing focus on lncRNA- and circRNA-mediated networks, inflammation, and biomarkers reflects a shift toward precision medicine and innovative therapeutic interventions. These findings establish a foundation for future molecular diagnostics and targeted therapies, bridging the gap between research and clinical practice.; ",26,1,,,Ischemic stroke; Stroke (engine); Medicine; Physical medicine and rehabilitation; Internal medicine; Ischemia; Engineering; Mechanical engineering,,,,Universiti Tunku Abdul Rahman; Universiti Tunku Abdul Rahman; Ministry of Higher Education Fundamental Research Grant Scheme,https://jmhg.springeropen.com/counter/pdf/10.1186/s43042-025-00687-7 https://doi.org/10.1186/s43042-025-00687-7,http://dx.doi.org/10.1186/s43042-025-00687-7,,10.1186/s43042-025-00687-7,,,0,000-037-075-981-923; 005-232-677-140-916; 006-181-420-837-338; 010-223-756-159-523; 010-532-581-848-077; 010-538-248-481-854; 014-474-415-401-731; 015-407-921-194-591; 023-212-303-927-997; 025-593-748-836-312; 027-662-226-294-949; 028-014-471-457-079; 032-783-802-369-155; 033-045-229-886-978; 035-166-216-484-121; 036-198-544-545-678; 036-208-357-476-626; 036-412-491-751-869; 040-741-785-168-654; 044-521-806-844-035; 053-508-635-593-584; 053-856-102-674-155; 060-110-487-280-490; 069-881-836-530-412; 069-965-991-071-699; 070-509-113-412-927; 074-982-556-173-776; 079-113-306-611-152; 081-845-775-919-542; 093-249-139-880-696; 094-219-554-357-113; 099-044-389-593-904; 099-903-091-873-826; 100-039-324-958-367; 108-947-841-274-881; 110-845-944-246-394; 119-572-219-538-227; 125-417-251-458-70X; 138-917-099-476-032; 153-687-463-825-941; 157-197-211-109-010; 159-187-294-031-709; 160-758-986-044-211; 163-176-419-720-948; 184-047-909-209-270; 198-430-325-979-458,1,true,cc-by,gold -175-800-647-097-459,Global research and research progress on climate change and their impact on plant phenology: 30 years of investigations through bibliometric analysis,2024-03-14,2024,journal article,Theoretical and Applied Climatology,0177798x; 14344483,Springer Science and Business Media LLC,Germany,Pooja Singh; Baby Gargi; Prabhakar Semwal; Susheel Verma,,155,6,4909,4923,Climate change; Phenology; Scopus; Bibliometrics; Geography; Physical geography; China; Regional science; Environmental resource management; Environmental science; Political science; Library science; Ecology; Computer science; Biology; Archaeology; MEDLINE; Law,,,,Not applicable,,http://dx.doi.org/10.1007/s00704-024-04919-5,,10.1007/s00704-024-04919-5,,,0,001-286-960-958-252; 001-498-869-192-625; 002-052-422-936-00X; 002-092-842-194-504; 003-332-834-084-571; 005-121-917-796-876; 005-198-779-150-932; 007-197-476-300-460; 013-507-404-965-47X; 014-285-435-837-468; 015-293-683-804-610; 016-077-753-336-77X; 017-125-438-023-941; 018-358-569-970-029; 018-791-149-528-442; 019-189-723-505-363; 020-650-747-735-866; 024-847-305-221-512; 025-035-576-100-440; 028-293-472-890-24X; 029-340-960-234-28X; 034-548-585-569-70X; 034-768-039-318-254; 038-032-722-504-530; 038-303-862-037-649; 040-916-905-850-714; 041-684-158-951-736; 042-759-733-062-258; 045-636-583-989-275; 046-729-998-989-866; 046-746-857-938-621; 046-992-864-415-70X; 047-915-240-613-449; 050-147-313-218-474; 055-497-099-256-606; 059-038-327-622-923; 061-825-542-250-266; 063-128-291-912-147; 065-622-397-050-895; 067-798-631-762-594; 072-073-635-951-774; 078-845-448-111-118; 079-302-093-411-204; 082-758-584-450-623; 084-145-409-872-475; 087-601-676-909-135; 094-170-683-236-698; 108-460-015-955-613; 110-396-699-639-539; 119-239-907-673-220; 124-333-530-664-827; 143-720-999-866-185; 158-393-747-114-701; 163-723-921-018-951; 166-562-044-678-513; 166-879-319-070-474; 173-919-812-907-722; 175-429-461-075-08X; 181-902-568-708-973; 183-966-784-262-377; 192-571-432-639-775; 195-634-649-019-686; 198-054-264-168-558,4,false,, -175-849-392-440-573,Finding the new potential research on diabetic kidney disease and hemodialysis in healthcare insurance databases: A bibliometric analysis.,2024-10-09,2024,journal article,Narra J,28072618,Narra Sains Indonesia,Indonesia,Lily Kresnowati; Suhartono Suhartono; Zahroh Shaluhiyah; Bagoes Widjanarko,"To the best of our knowledge, bibliometric analysis has not been performed for studies related to diabetic kidney disease (DKD) and hemodialysis using healthcare big data. Herein, the aim of this bibliometric analysis was to identify emerging research trends in DKD and hemodialysis within healthcare insurance databases by exploring authors, co-author networks, and countries to discover new potential research areas. A bibliometric study was conducted, utilizing data obtained from the Scopus database. Keywords such as diabetic kidney disease, hemodialysis, insurance or big data, and prediction were employed. Inclusion criteria were original articles and review articles written in English published between 2010 and 2022. VOSviewer and the Bibliometrix package in R were used for comprehensive bibliometric analysis. VOSviewer facilitated keyword co-occurrence analysis to identify clusters and visualize relationships among keywords, emphasizing distinct research themes, keyword density, and network visualization. Meanwhile, Bibliometrix allowed exploration of key metrics such as prolific authors and institutions, publication trends, co-authorship networks, citations, document types, emerging trends through keyword analysis, and network visualizations, including co-authorship and keyword co-occurrence. Results from both tools were integrated for a thorough analysis. The present study yielded 2,199 articles, which was reduced to 1,828 after removing duplicates and applying inclusion criteria. This bibliometric analysis found that machine learning and artificial intelligence are emerging yet remain relatively under-researched in the context of hemodialysis and DKD. The prominence of topics such as diabetic nephropathy, non-insulin treatments, and lifestyle modifications highlighted ongoing research priorities in DKD and hemodialysis. Taiwan's dominance in publications suggested robust research activity in this field, while international collaboration underscored global interest and the potential for diverse research perspectives. The need for similar research development in Indonesia, leveraging big data and machine learning, indicates opportunities for advancing the understanding and management of DKD and hemodialysis within the region.",4,3,e827,e827,Scopus; Bibliometrics; Context (archaeology); Computer science; Health care; Big data; Data science; Medicine; MEDLINE; Data mining; Geography; Political science; Law; Archaeology,Diabetic kidney disease; bibliometric; health insurance; hemodialysis; machine learning,"Renal Dialysis; Bibliometrics; Humans; Diabetic Nephropathies/therapy; Databases, Factual; Insurance, Health/statistics & numerical data; Biomedical Research; Big Data",,,,http://dx.doi.org/10.52225/narra.v4i3.827,39816104,10.52225/narra.v4i3.827,,PMC11731930,0,002-447-526-369-78X; 004-987-289-507-025; 005-841-581-694-82X; 011-477-320-780-817; 014-147-544-881-868; 016-260-483-697-107; 024-063-629-616-70X; 030-706-471-503-580; 037-439-109-022-259; 038-163-940-975-744; 038-660-893-572-973; 046-625-087-779-909; 048-125-930-180-089; 054-080-517-242-283; 060-381-675-535-061; 087-766-091-936-598; 095-204-541-832-696; 109-860-178-146-879; 117-363-492-759-502; 119-442-755-003-394; 122-037-285-779-161; 130-254-592-063-404; 157-579-205-503-832; 168-936-001-953-059; 190-249-582-505-213; 192-136-455-684-601; 197-354-259-085-502,0,true,,unknown -175-916-910-589-659,Intelligent Materials Improvement Through Artificial Intelligence Approaches: A Systematic Literature Review,2024-07-11,2024,journal article,Archives of Computational Methods in Engineering,11343060; 18861784,Springer Science and Business Media LLC,Spain,José G. B. A. Lima; Anderson S. L. Gomes; Adiel T. de Almeida-Filho,,32,2,693,705,Computer science; Artificial intelligence; Engineering,,,,Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco; Conselho Nacional de Desenvolvimento Científico e Tecnológico,,http://dx.doi.org/10.1007/s11831-024-10163-x,,10.1007/s11831-024-10163-x,,,0,000-965-405-051-051; 001-306-231-957-378; 003-253-884-487-920; 005-473-137-816-53X; 006-636-905-283-028; 010-700-442-333-786; 011-126-186-985-074; 011-678-640-066-63X; 013-507-404-965-47X; 017-750-600-412-958; 018-750-773-959-499; 020-278-725-509-528; 020-589-901-579-161; 026-626-040-365-839; 033-825-242-245-363; 037-105-776-401-471; 039-349-573-826-692; 042-697-162-107-449; 046-274-419-844-34X; 051-472-459-766-495; 056-557-304-127-52X; 059-149-073-001-124; 062-629-108-214-324; 071-935-791-977-749; 075-473-922-786-232; 083-336-106-936-449; 086-131-894-877-186; 087-969-457-602-614; 088-872-505-031-250; 090-176-157-030-077; 090-182-186-756-679; 090-914-220-981-783; 093-407-022-562-599; 100-209-722-983-786; 110-376-904-552-777; 111-275-481-454-465; 121-915-959-923-124; 132-308-279-448-387; 132-930-002-151-759; 139-560-069-415-623; 147-242-097-817-554; 163-139-640-894-354; 163-426-857-930-573; 165-836-490-565-104,0,false,, -175-929-496-157-270,Suitability of scienciometric analysis targeting Loop Mediated Isothermal Amplification Assay applied to farm animals / Adequação da análise cienciométrica direcionada ao ensaio de Amplificação Isotérmica Mediada por Alça aplicada à animais de produção,2021-12-29,2021,journal article,Brazilian Journal of Development,25258761,South Florida Publishing LLC,,Sarah Amado Ribeiro; Calebe Bertolino Marins De Campos; Hérida Samaya Gonçalves De Sousa; Alex Silva Da Cruz; Aparecido Divino Da Cruz,"The objective of the study was to carry out, with the aid of Scopus®️, a scientometric analysis of Loop Mediated Isothermal Amplification Assay (LAMP) applied to farm animals. The research has considered articles from January 2000 to December 2019 and only open or closed access articles published in English. The bibliometric matrices were run through RStudio, applying Biblioshiny as a web interface to Bibliometrix resources for R environment. Later, several bibliometric data were collected with the aid of Bibliometrix, most of which were converted into graphs using Microsoft Excel®️. The scientometric analysis base of the current study was composed by 438 articles from 504 researched in the Scopus®️. Of the 438 articles analyzed, it stands out as results: 1) the years of 2015 (11,4%) and 2019 (11,4%) had equally the highest number of publications in the area; 2) Journal of Virological Methods (12,5%) ranked first in the ranking of journals according to total articles published; 3) China (49,8%), Japan (12,7%) and India (7,1%) have been countries of more published articles; 4) most articles applied the assay to detect microorganisms affecting the farm animals; and, 5) together, the animal groups fish, bovine, poultry, and swine corresponded to 2/3 (71,1%) of the animals used in scientific research using the LAMP method. With all these results, it is concluded that the scientometric analysis showed an overview of the information in the articles about LAMP applied to farm animals.",7,12,115333,115354,Scopus; Web of science; Microsoft excel; Loop-mediated isothermal amplification; Agricultural science; Library science; Computer science; Chemistry; Biology; Operating system; MEDLINE; Biochemistry; DNA,,,,,,http://dx.doi.org/10.34117/bjdv7n12-345,,10.34117/bjdv7n12-345,,,0,,0,true,,gold -176-010-535-784-633,Exploring the Evolution of Human Resource Analytics: A Bibliometric Study.,2023-03-10,2023,journal article,"Behavioral sciences (Basel, Switzerland)",2076328x,,Switzerland,Eithel F Bonilla-Chaves; Pedro R Palos-Sánchez,"The objective of this study is to identify and analyze the most relevant scientific work being undertaken in HR analytics. Additionally, it is to understand the evolution of the conceptual, intellectual, and social structure of this topic in a way that allows the expansion of empirical and conceptual knowledge. Bibliometric analysis was performed using Bibliometrix and Biblioshiny software packages on academic articles indexed on the Scopus and Web of Science (WoS) databases. Search criteria were applied, initially resulting in a total of 331 articles in the period 2008-2022. Finally, after applying exclusion criteria, a total of 218 articles of interest were obtained. The results of this research present the relevant notable topics in HR analytics, providing a quantitative analysis that gives an overview of HR analytics featuring tables, graphs, and maps, as well as identifying the main performance indicators for the production of articles and their citations. The scientific literature on HR analytics is a novel, adaptive area that provides the option to transform traditional HR practices. Through the use of technology, HR analytics can improve HR strategies and organisational performance, as well as people's experiences.",13,3,244,244,Analytics; Data science; Resource (disambiguation); Computer science; Computer network,HR analytics; bibliometric analysis; bibliometrix; management and organisational behaviour; people analytics; strategic HRM practices,,,,https://www.mdpi.com/2076-328X/13/3/244/pdf?version=1678445212 https://doi.org/10.3390/bs13030244,http://dx.doi.org/10.3390/bs13030244,36975268,10.3390/bs13030244,,PMC10045487,0,000-085-978-509-642; 001-396-603-234-771; 002-291-107-672-727; 003-150-136-257-466; 004-182-220-671-291; 006-583-479-646-036; 008-644-201-338-417; 009-181-661-133-058; 013-507-404-965-47X; 014-323-682-978-166; 015-588-960-822-808; 015-692-170-714-052; 016-814-329-999-168; 017-300-737-144-757; 017-750-600-412-958; 022-182-599-479-036; 024-883-499-251-514; 026-229-684-910-506; 026-696-204-998-266; 030-662-675-189-130; 034-600-684-728-898; 037-036-602-845-527; 037-815-640-424-494; 042-474-047-254-816; 044-201-223-809-024; 047-134-478-431-993; 052-329-359-475-089; 054-818-565-070-154; 057-044-263-941-420; 057-058-693-769-402; 065-516-419-444-125; 069-012-932-803-578; 071-468-917-263-70X; 075-134-214-781-08X; 076-757-389-392-083; 078-757-368-245-538; 084-026-774-797-731; 084-283-306-599-774; 089-376-060-537-606; 095-727-624-068-956; 095-961-443-609-384; 097-134-463-718-899; 100-215-709-928-548; 100-983-743-964-229; 102-564-084-265-956; 104-826-193-676-076; 110-172-537-905-096; 115-750-390-051-228; 117-137-754-620-717; 121-448-636-351-344; 134-181-543-786-906; 139-521-514-995-143; 143-399-973-125-524; 147-199-278-864-535; 153-108-877-433-279; 154-548-739-676-737; 163-530-964-806-770; 165-554-700-188-584; 173-178-374-948-675; 175-985-894-679-556,41,true,cc-by,gold -176-227-528-602-472,"Statistical Analysis of Risk Factors with Overweight-Diabetes and Gut Microbiota, a Bibliometric Analysis Using Bibliometrix",2024-01-01,2024,journal article,Acta Scientifci Nutritional Health,25821423,Acta Scientific Publications Pvt. Ltd.,,Tell-Morinson Melba; Menco-Tovar Andrea; Barrero-Jiménez Erika; Moreno-Novoa Melissa; Mendez-Ramos Maria,"Sceintific production on chronic non-communicable diseases such as overweight, obesity and diabetes has grown in recent years.However, there is no comprehensive overview of the study designs and statistical analysis methodologies commonly used for risk assessment of research conducted on this topic.In order to evaluate risk assessment in this field, 1190 relevant documents downloaded using markers were included: (""Risk-Factors Associated with Overweight"" or ""Risk-Factors Associated with Obesity"" or ""Risk-Factors Associated with diabetes"") and (microbiome or diabetes) and ""multivariate analysis"", in publications retrieved between 2017-2022 from the PubMed database; Specific parameters of title, journal, year of publication, authors, country of origin, institution, authors, keywords, among others, were analyzed.Data analysis was performed in three stages: 1. Descriptive; 2. Networking for Bibliographic Coupling Analysis (Network); 3. Strength of association of bibliographic coupling (Normalization).Data Visualization comprised: a.A mapping of the conceptual structure with Multiple Correspondence Analysis (MCA) for qualitative variables; b Network mapping.Grouping (Clustering) of K-means to identify groups of documents that express common concepts.To automate the data analysis and visualization stages, the open source tool (bibliometrix R-package), developed in R language, was used.68.6% of the variability of the ables.Most study methods -study design, analysis methodology -are based on continuous measurement variables, commonly using methods based on distributions such as normal for statistical analysis.In clinical epidemiology, where statistical methodology is applied to the study of diseases, their occurrence, distribution and relationship with explanatory variables, confronts us with variables of interest with distributions that are not continuous.Commonly continuous measurement variables become dichotomous",,,2,11,Overweight; Obesity; Gut flora; Diabetes mellitus; Statistical analysis; Environmental health; Medicine; Statistics; Internal medicine; Mathematics; Endocrinology; Immunology,,,,,,http://dx.doi.org/10.31080/asnh.2024.08.1334,,10.31080/asnh.2024.08.1334,,,0,,0,true,,gold -176-350-617-108-891,Flood Mitigation Techniques Using Storm Water Harvesting Methods: A Bibliometric Analysis,2022-09-13,2022,journal article,Science & Technology Libraries,0194262x; 15411109,Informa UK Limited,United States,Jasna Bhargavan; A .K. Kasthurba; Anjana Bhagyanathan,"This paper tries to breakdown 12 years of research on storm water harvesting systems that can aid in flood mitigation by methodically evaluating the existing literature and identifying relevant research gaps. Bibliometric co-citation meta-analysis is used to understand decentralized storm water harvesting methods that can aid in flood management. 165 articles from multiple disciplines in scopus database are used in this study to identify literature pertaining to flood mitigation techniques using storm water harvesting methods. Further these articles where analyzed for their scientific productivity, relevance and collaboration. Also the VOS viewer software and Bibliometrix R Package software were employed for visualization. The results of this study revealed that most of such studies focus on urban context. Thus, the study offers academics and practitioners a pertinent multidisciplinary platform for research on urban water security and encourages the growth of further knowledge on this subject.",42,3,285,296,Flood myth; Context (archaeology); Relevance (law); Computer science; Multidisciplinary approach; Storm; Scopus; Data science; Environmental science; Geography; Sociology; Meteorology; Political science; Social science; Archaeology; MEDLINE; Law,,,,,,http://dx.doi.org/10.1080/0194262x.2022.2116144,,10.1080/0194262x.2022.2116144,,,0,003-432-703-387-773; 005-220-762-250-505; 007-278-724-576-576; 009-280-999-054-238; 009-584-712-816-016; 009-777-374-198-489; 011-729-036-351-757; 013-507-404-965-47X; 016-559-039-101-721; 016-673-014-496-439; 020-053-806-184-529; 025-689-740-445-68X; 026-504-241-766-289; 043-384-119-593-831; 045-189-487-279-175; 048-552-731-046-334; 053-342-265-116-571; 053-842-487-795-662; 058-377-931-405-597; 058-820-639-089-922; 059-165-647-122-890; 062-522-363-687-348; 062-738-263-751-026; 064-348-719-100-627; 065-843-236-303-993; 066-087-005-974-429; 076-362-012-282-718; 079-835-991-499-254; 088-780-735-257-070; 091-121-482-111-485; 093-706-291-720-719; 104-572-756-470-024; 106-189-132-073-689; 106-435-216-563-053; 106-838-078-868-68X; 110-982-039-697-954; 111-336-684-142-919; 112-160-300-331-703; 113-528-794-385-70X; 117-552-481-375-178; 118-269-712-388-930; 132-556-791-227-412; 135-468-293-524-966; 156-295-939-086-774,3,false,, -176-708-204-002-208,Exploring Methodologies in ICT-Enabled Community Development: Bibliometrix Analysis,2024-12-17,2024,conference proceedings article,2024 International Conference on Intelligent Cybernetics Technology & Applications (ICICyTA),,IEEE,,Mega Fitri Yani; Luthfi Ramadani; Iqbal Yulizar Mukti,,,,42,47,Information and Communications Technology; Computer science; World Wide Web,,,,,,http://dx.doi.org/10.1109/icicyta64807.2024.10913461,,10.1109/icicyta64807.2024.10913461,,,0,005-651-804-904-728; 008-639-092-309-361; 013-057-355-416-478; 014-295-652-418-840; 018-830-196-674-003; 022-268-037-685-476; 026-241-568-943-759; 029-032-152-283-230; 045-391-792-409-57X; 048-541-870-771-866; 055-483-037-073-022; 064-459-386-931-917; 067-962-733-413-792; 081-043-527-729-50X; 083-248-783-042-338; 086-324-309-823-998; 087-994-971-299-608; 100-932-226-758-814; 104-867-414-759-82X; 182-432-285-652-255,0,false,, -176-728-482-650-094,Emerging themes and future directions in space radiation health research: a bibliometric exploration from 2013 to 2022.,2025-03-29,2025,journal article,Radiation and environmental biophysics,14322099; 0301634x,Springer Science and Business Media LLC,Germany,Jianhui Tan; Zhongming Zhou; Huihui Zheng; Yanpo Li; Haiting Wang; Qiuping Yang; Huiting Tian; Haolin Chen; Jiayi Xie; Zhiyang Li; Yexi Chen,"The impact of space radiation on health (SRHE) is extensive and significantly influences public health and space operations, making it essential to analyze global collaboration networks and track developmental trends over the last decade. However, bibliometric analysis in this area remains limited. This study aims to outline publication trends, citation patterns, major journals, key authors, institutional and national collaborations, and to explore emerging themes and future directions. A bibliometric analysis was conducted using CiteSpace, Bibliometrix in R, and VOSviewer on SRHE research from the Web of Science Core Collection up to November 12, 2023. The analysis included 390 records from 4,857 journals, involving 1,918 authors across 701 institutions in 53 countries. The predominant publications were Articles and Review Articles in Life Sciences and Biomedicine, with a notable publication surge in 2020. The most cited work was by Li et al. (2017), with Cucinotta F.A. as the most prolific author. The USA led in publications, citations, and collaboration strength, followed by Germany and China. Key journals include Radiation Research, Plos One, Life Sciences in Space Research, and Health Physics. Research has focused on radiation exposure effects, DNA damage repair, astronaut health risks, and radiation protection, with emerging trends in microgravity, astrobiology, and lifespan research, which examines the biological, psychological, and social aspects of aging and the entire life course, aiming to understand and extend the health span-the period of life free from chronic diseases and age-related disabilities-rather than just the total lifespan. Future research may benefit from focusing on personalized radiation protection, exploring biological mechanisms, and embracing technological innovations, based on the trends observed in this study.",64,2,211,227,Citation; Biomedicine; Web of science; China; Life course approach; Space radiation; Space (punctuation); Library science; Political science; Psychology; MEDLINE; Computer science; Physics; Biology; Bioinformatics; Cosmic ray; Operating system; Social psychology; Astrophysics; Law,Bibliometrix; CiteSpace; Health effects; Radiation protection; Space radiation; VOSviewer,Bibliometrics; Humans; Cosmic Radiation; Radiobiology,,"The Special Fund Project of Guangdong Science and Technology ((210728156901524, 210728156901519)); Guangdong Medical Research Foundation (A2023481); Shantou Medical Science and Technology Planning Project (220518116490772,220518116490933)",,http://dx.doi.org/10.1007/s00411-025-01115-5,40156613,10.1007/s00411-025-01115-5,,PMC12049392,0,007-872-835-877-664; 009-624-184-852-980; 011-853-952-591-754; 011-934-232-539-426; 012-475-564-942-154; 015-372-616-293-414; 015-565-673-103-913; 017-751-288-704-730; 018-149-793-575-858; 018-483-239-245-476; 021-286-359-616-257; 024-977-468-429-807; 025-809-588-414-101; 029-282-815-645-434; 041-802-644-837-095; 044-335-593-479-521; 046-556-814-622-515; 052-893-080-179-343; 055-824-679-937-219; 057-471-243-786-503; 066-214-905-365-935; 068-443-075-804-434; 074-550-796-051-883; 075-088-928-548-904; 088-406-272-721-155; 098-313-643-360-767; 108-570-218-772-902; 109-114-133-063-354; 114-575-915-926-460; 115-084-008-776-294; 116-055-544-270-08X; 117-946-811-844-531; 118-999-050-613-274; 121-665-008-344-953; 129-892-454-220-935; 135-047-217-829-172; 142-736-839-157-11X; 146-904-493-710-031; 153-205-530-695-135; 162-156-857-275-392; 172-014-262-374-905; 181-364-048-174-781; 186-562-381-668-485; 188-741-297-687-604; 193-849-167-884-517; 195-018-166-545-439; 195-681-331-881-323; 199-062-943-661-439,0,true,cc-by-nc-nd,hybrid -176-965-438-762-004,Past and future of Industry 4.0: a bibliometric review using bibliometrix and VOSviewer,,2023,journal article,International Journal of Learning and Change,17402875; 17402883,Inderscience Publishers,Switzerland,Madalena Araújo; António Amaral; Nelson Duarte; Filipe Machado,,1,1,,,Engineering; Management science; Data science; Computer science; Knowledge management,,,,,,http://dx.doi.org/10.1504/ijlc.2023.10057435,,10.1504/ijlc.2023.10057435,,,0,,0,false,, -177-021-948-130-515,The evaluation of AI integration in innovative digital marketing strategies,2023-09-30,2023,journal article,Pressacademia,21467943,Pressacademia,,Ibrahim Halil Efendioglu,"Purpose- This study aims to provide a bibliometric review of publications where the terms 'digital marketing' and 'artificial intelligence' are used together. Leading publications, authors, countries, and institutions in the Web of Science (WoS) database have been examined to achieve this goal. Additionally, this article investigates the combined use of digital marketing and artificial intelligence. Furthermore, it aims to offer insights into artificial intelligence strategies for marketing that businesses can employ. ; Methodology- The research employs the technique of bibliometric analysis. The Bibliometrix package within R Studio and its web-based component, Biblioshiny, were utilized for analysis. Searches were conducted in the Web of Science database using the keywords 'Digital Marketing' and 'Artificial Intelligence' in the title, abstract, and keywords sections.; Findings- As a result of the analysis, a total of 60 publications authored by 140 researchers and distributed across 46 journals between 2017 and 2023 were identified. Examination of the included publications reveals frequent usage of terms such as 'artificial intelligence,' 'creativity,' 'analytics,' 'impact,' 'expertise,' 'social networks,' 'big data,' 'governance,' 'success,' and 'AI.' Upon scrutinizing the authors' countries, India emerged as the leading contributor, followed by Spain and the USA. Moreover, Finland (370), Spain (92), and France (58) had the highest citation counts.; Conclusion- This research aims to contribute to researchers interested in working in digital marketing and artificial intelligence by examining its past and present. For this purpose, 60 relevant studies from the literature were systematically reviewed and analyzed across various categories. Additionally, the examined publications' conceptual, intellectual, and social structures were illuminated.; ; Keywords: Digital marketing, artificial intelligence, AI systems, bibliometric analysis, bibliometrix.; JEL Codes: M15, M30, M31; ",,,,,Web intelligence; Digital marketing; Creativity; Computer science; Big data; Marketing research; Marketing and artificial intelligence; Digital library; Analytics; Web of science; Knowledge management; Data science; Artificial intelligence; The Internet; World Wide Web; Marketing; Psychology; Political science; Business; Data mining; Intelligent decision support system; Social psychology; Web development; Art; Poetry; Literature; MEDLINE; Law,,,,,,http://dx.doi.org/10.17261/pressacademia.2023.1820,,10.17261/pressacademia.2023.1820,,,0,,1,true,,gold -177-024-578-267-576,Inovações no Reconhecimento e Detecção de Animais: Uma Análise da Literatura com Ênfase em Redes Neurais e Aprendizado de Máquina,2023-10-19,2023,conference proceedings article,Anais do XVI Encontro Unificado de Computação do Piauí (ENUCOMPI 2023),,Sociedade Brasileira de Computação,,Raquel M. A. Nolêto; Carleandro Nolêto; Natanael P. S. Santos; Aline M. A. Madeira,"O desenvolvimento de novas formas de reconhecimento de animais na agropecuária é algo desafiador, podendo ser considerado complexo de ser implementado. Este artigo tem por objetivo fornecer uma revisão sistemática da aplicação de redes neurais convolucionais e aprendizado de máquina no reconhecimento de animais por imagens. Os dados foram coletados a partir de um estudo bibliométrico para mapear a produção acadêmica, utilizando a plataforma Web of Science (WoS) e o pacote Bibliometrix do software R. Com essa pesquisa, foi possível observar o uso de redes neurais na pecuária e sua eficácia na previsão da produção e características de animais individuais.",,,33,40,Humanities; Computer science; Physics; Art,,,,,https://sol.sbc.org.br/index.php/enucompi/article/download/26614/26437 https://doi.org/10.5753/enucompi.2023.26614,http://dx.doi.org/10.5753/enucompi.2023.26614,,10.5753/enucompi.2023.26614,,,0,,1,true,,bronze -177-241-437-949-160,"Multi-criteria classification, sorting, and clustering: a bibliometric review and research agenda",2022-09-30,2022,journal article,Annals of Operations Research,02545330; 15729338,Springer Science and Business Media LLC,Netherlands,Sarah Ben Amor; Fateh Belaid; Ramzi Benkraiem; Boumediene Ramdani; Khaled Guesmi,,325,2,771,793,Multiple-criteria decision analysis; Cluster analysis; Computer science; Sorting; Field (mathematics); Transparency (behavior); Data science; Management science; Data mining; Operations research; Artificial intelligence; Engineering; Mathematics; Computer security; Pure mathematics; Programming language,,,,,,http://dx.doi.org/10.1007/s10479-022-04986-9,,10.1007/s10479-022-04986-9,,,0,001-182-491-259-769; 003-031-552-484-914; 004-327-760-003-918; 004-558-109-656-838; 006-000-805-186-913; 006-042-531-269-185; 008-239-711-320-664; 008-859-600-376-785; 009-736-098-876-691; 011-057-730-368-453; 011-364-541-838-073; 012-641-663-921-675; 012-658-359-692-098; 012-985-141-250-279; 013-507-404-965-47X; 014-222-903-488-222; 015-907-474-638-226; 017-750-600-412-958; 018-546-863-535-616; 019-342-916-337-210; 019-571-214-559-803; 019-945-777-878-166; 021-143-061-399-28X; 021-826-835-587-878; 022-126-766-800-063; 023-353-698-753-221; 023-597-317-253-663; 024-555-814-750-91X; 025-287-714-364-446; 025-834-561-655-145; 026-970-052-770-383; 027-686-672-596-900; 027-772-272-465-734; 031-147-611-592-967; 031-812-376-168-660; 033-733-701-787-068; 034-462-943-992-667; 034-669-422-274-30X; 034-817-247-853-495; 035-159-505-199-698; 035-801-598-288-440; 036-784-682-767-502; 036-961-780-130-868; 037-036-602-845-527; 037-811-831-413-992; 037-970-992-137-552; 039-081-048-503-970; 040-733-098-951-591; 041-124-398-281-174; 042-579-641-882-277; 042-790-278-925-394; 044-172-895-117-573; 044-591-783-098-693; 044-663-551-203-642; 045-440-492-677-028; 045-836-584-456-776; 048-550-586-067-411; 048-611-860-534-614; 051-057-058-496-107; 053-015-734-806-076; 053-152-290-226-935; 054-338-478-019-470; 054-818-565-070-154; 055-205-519-075-768; 057-696-721-421-056; 059-386-311-958-247; 060-939-890-875-317; 061-729-548-133-378; 062-447-112-934-802; 062-679-546-940-292; 063-644-822-256-187; 063-672-372-247-467; 066-181-236-732-161; 066-690-171-919-798; 067-513-390-568-317; 068-229-620-175-614; 068-745-352-789-134; 072-605-026-469-231; 073-241-184-971-35X; 075-589-226-291-417; 075-757-359-771-342; 075-772-304-814-988; 078-826-542-935-320; 079-925-407-613-097; 080-026-073-033-725; 080-830-685-226-453; 081-121-667-434-00X; 081-335-941-178-525; 082-859-595-880-285; 084-164-987-604-644; 084-679-969-667-599; 085-139-094-519-321; 087-874-301-901-819; 088-756-008-635-08X; 090-359-826-110-595; 090-992-533-777-824; 091-804-945-487-650; 093-573-032-396-583; 095-266-983-031-056; 096-101-277-209-807; 096-851-238-164-477; 099-689-351-674-029; 102-406-729-578-244; 102-423-994-932-499; 104-080-920-278-835; 105-028-265-648-083; 105-725-344-228-216; 107-648-247-995-014; 109-742-950-126-05X; 112-048-828-636-783; 117-250-486-706-85X; 119-153-326-190-215; 119-622-503-622-138; 120-885-678-404-810; 124-457-056-801-218; 127-655-403-797-492; 127-899-183-292-505; 128-681-425-941-390; 128-685-350-619-767; 131-226-012-439-080; 131-634-274-914-470; 132-354-223-857-234; 132-414-570-749-301; 134-673-568-138-228; 139-304-925-242-559; 147-067-465-063-958; 148-402-069-524-419; 148-738-194-511-931; 149-409-479-660-411; 160-080-357-268-291; 161-173-768-203-846; 171-541-560-610-45X; 177-620-686-806-937; 180-611-453-215-38X; 180-952-857-432-968,28,false,, -177-263-865-740-045,Citation Behaviour of Physics and Astronomy Researchers in the Western Himalayan Region,2024-04-04,2024,journal article,DESIDOC Journal of Library & Information Technology,09764658; 09740643,Defence Scientific Information and Documentation Centre,India,Muruli N; N. S. Harinarayana,"The study aims to examine the citation behaviour of Physics and Astronomy researchers from Indian central universities in the Western Himalayan region. By employing Bibliometrix and Biblioshiny packages in R Studio, an analysis of 13,065 cited sources was conducted using data from the Scopus database over a ten-year span (2012- 2021). The findings highlight a preference for influential journal articles and reviews, with an inclination towards articles authored by two or three individuals. These findings offer valuable insights for stakeholders including researchers, policymakers, and funders, to enhance research impact in the region. The study also draws attention to ‘undefined’ tags in bibliographic data and calls for refinement in defining metadata to enhance bibliographic data quality and reliability.",44,2,88,94,Citation; Astronomy; Physics; Library science; Computer science,,,,,https://publications.drdo.gov.in/ojs/index.php/djlit/article/download/19265/8268 https://doi.org/10.14429/djlit.44.2.19265,http://dx.doi.org/10.14429/djlit.44.2.19265,,10.14429/djlit.44.2.19265,,,0,,0,true,,gold -177-717-821-804-928,Bibliometric study about sustainable tourism product in Scopus database,,2023,journal article,Revista interamericana de ambiente y turismo,0718235x; 07176651,SciELO Agencia Nacional de Investigacion y Desarrollo (ANID),,Cliver Samuel Castillo-Quiñones; Beatriz Serrano-Leyva; Félix Díaz-Pompa,"Sustainability in the tourism sector, environmental conservation, and the benefit of local communities are some of the topics that currently arouse the greatest interest. The objective of this research is to map the scientific production on sustainable tourism products available in the Scopus database. The bibliometric method was used. The information was processed in the Biblioshiny application of the Bibliometrix package of RStudioCloud. Productivity and citation indicators were calculated by years, journals, authors, documents, institutions, and countries. Xavier Font as the most prolific and high-impact author, Sustainability (Switzerland) as the most productive journal, and Tourism Management as the most cited journal were relevant. China is the country with the largest number of publications on the subject. Finally, a content analysis of articles was carried out to identify as research trends the value of environmental certifications, the behavior of the customer segment with environmental priorities, and sustainability and community-based tourism entrepreneurship.",19,1,90,99,Scopus; Tourism; Sustainability; China; Product (mathematics); Productivity; Certification; Sustainable tourism; Business; Entrepreneurship; Citation; Geography; Marketing; Regional science; Political science; Library science; Economic growth; Economics; Management; Computer science; Ecology; Geometry; Mathematics; MEDLINE; Archaeology; Finance; Law; Biology,,,,,http://www.scielo.cl/pdf/riat/v19n1/0718-235X-riat-19-01-90.pdf https://doi.org/10.4067/s0718-235x2023000100090,http://dx.doi.org/10.4067/s0718-235x2023000100090,,10.4067/s0718-235x2023000100090,,,0,,0,true,cc-by-nc,gold -178-187-116-177-675,The conceptual bibliometric analysis applied to the tourism-culture binomial 1995-2020,,2023,journal article,PASOS. Revista de Turismo y Patrimonio Cultural,16957121; 2529959x,University of La Laguna,,Rosario Díaz Ortega; Alexander Aguirre Montero; José Antonio López Sánchez,"This article aims to find out how the terms tourism and culture have been treated throughout history and when they began to be of interest to the scientific community as a result of the change in the conceptual mentality of the tourism sector in general and the tourist in particular, as well as to understand the evolutionary stage reached. To this end, bibliometric analysis has been carried out, based on a quantitative and systematic review of the literatura, using the Web of Science (WoSCC) database. The software used is Vosviewer and Bibliometrix to generate graphs and maps of relationships and clusters... We can highlight the degree of connection that exists between all the articles published in the period studied (1995 to 2020) due to the number of citations made. This work aims to identify the main trends in research on cultural tourism.",21,1,53,67,Tourism; Regional science; Sociology; Bibliometrics; Social science; Geography; Library science; Computer science; Archaeology,,,,,https://riull.ull.es/xmlui/bitstream/915/31138/1/PS_21_1%20_%282023%29_04.pdf http://riull.ull.es/xmlui/handle/915/31138 https://rodin.uca.es/bitstream/10498/29168/1/PC2023_0006.pdf https://hdl.handle.net/10498/29168,http://dx.doi.org/10.25145/j.pasos.2023.21.004,,10.25145/j.pasos.2023.21.004,,,0,,3,true,cc-by-nc-nd,gold -178-485-066-906-440,Doing more with less: An integrative literature review on responsible consumption behaviour,2023-04-20,2023,journal article,Journal of Consumer Behaviour,14720817; 14791838,Wiley,United States,Priya Nangia; Sanchita Bansal; Park Thaichon,"AbstractThe purpose of this research is to critically review the existing literature on responsible consumption behaviour (RCB) and identify the factors that influence it. Our findings are based on an integrative examination of 203 papers retrieved from the SCOPUS and WoS databases and analysed with the bibliometrix R software. Along with some descriptive insights into the field, we explain its intellectual structure informing future scholars about the field's evolution, and propose a future agenda for its advancement in the form, methodology, context, and themes. Five major themes emerged from our study: social values, corporate social responsibility (CSR), ethical obligations, environmental concern, and economic behaviour, which serve as a foundation for thematic future research directions. The implications for policymakers and management practice, as well as theoretical implications, are addressed.",23,1,141,155,Scopus; Consumption (sociology); Context (archaeology); Corporate social responsibility; Field (mathematics); Foundation (evidence); Thematic analysis; Sociology; Engineering ethics; Social science; Public relations; Political science; Qualitative research; MEDLINE; Law; Paleontology; Mathematics; Pure mathematics; Biology; Engineering,,,,,https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cb.2163 https://doi.org/10.1002/cb.2163 https://research-repository.griffith.edu.au/bitstreams/b1ac65f5-fbae-4233-9ae5-1a43a02072cd/download http://hdl.handle.net/10072/428519,http://dx.doi.org/10.1002/cb.2163,,10.1002/cb.2163,,,0,001-862-379-641-764; 001-997-313-277-638; 003-858-875-706-206; 006-709-382-973-154; 008-126-173-430-346; 008-277-726-480-019; 009-704-030-934-529; 010-268-730-045-842; 010-953-441-953-911; 011-395-755-285-576; 013-507-404-965-47X; 013-755-687-981-818; 015-247-825-597-147; 015-290-405-932-379; 016-223-314-677-698; 017-930-573-922-490; 018-675-134-759-186; 018-785-192-174-570; 020-839-304-257-681; 021-178-775-535-319; 022-459-234-232-654; 023-727-511-755-627; 023-776-017-503-61X; 024-134-920-505-680; 026-235-641-312-654; 027-237-742-021-042; 027-517-022-178-144; 029-254-599-297-544; 031-576-882-627-565; 032-877-814-800-00X; 034-457-072-748-979; 037-069-093-922-694; 039-165-194-872-916; 040-361-575-189-639; 040-681-403-881-752; 041-025-605-816-722; 044-339-379-658-535; 046-799-064-596-843; 046-891-125-275-544; 047-134-478-431-993; 049-220-041-092-419; 050-991-306-918-96X; 052-783-103-014-465; 053-162-510-491-239; 053-393-896-094-495; 054-676-157-322-315; 058-447-607-343-532; 059-767-777-680-573; 060-224-826-844-306; 061-339-784-496-345; 061-981-540-596-970; 067-307-773-608-817; 068-979-149-420-19X; 071-955-404-931-475; 073-545-316-581-71X; 075-004-097-669-017; 075-216-941-123-146; 075-560-686-125-285; 076-964-537-900-820; 077-589-831-249-930; 078-183-701-099-408; 080-763-044-871-009; 081-130-039-515-444; 081-471-478-306-017; 081-832-768-205-979; 082-939-933-669-651; 082-968-306-991-310; 094-691-050-086-97X; 099-676-003-852-658; 103-864-489-925-431; 105-155-288-082-408; 107-274-748-521-438; 110-416-068-447-448; 110-422-267-015-50X; 114-189-987-330-943; 124-290-094-991-487; 124-292-364-089-522; 127-882-990-076-103; 129-144-949-933-845; 129-475-105-628-804; 129-696-944-894-133; 129-966-022-560-687; 131-910-383-328-313; 132-769-452-255-776; 133-669-254-100-480; 135-966-845-015-054; 148-024-081-665-622; 155-638-924-269-100; 158-171-767-454-371; 171-914-083-221-433; 177-772-138-702-443; 183-199-866-533-084; 183-686-399-133-150; 187-825-110-604-058; 192-276-119-129-558; 193-917-296-674-219,28,true,cc-by-nc-nd,hybrid -178-633-694-456-032,Crosstalk between gut microbiota and cancer chemotherapy: current status and trends.,2024-12-24,2024,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Shanshan Yang; Shaodong Hao; Hui Ye; Xuezhi Zhang,"Chemotherapy is crucial in the management of tumors, but challenges such as chemoresistance and adverse reactions frequently lead to therapeutic delays or even premature cessation. A growing body of research underscores a profound connection between the gut microbiota (GM) and cancer chemotherapy (CC). This paper aims to pinpoint highly influential publications and monitor the current landscape and evolving trends within the realm of GM/CC research.; On October 1st, 2024, a comprehensive search for GM/CC publications spanning the past 20 years from 2004 to 2023 was conducted utilizing the Web of Science Core Collection (WoSCC). The scope encompassed both articles and reviews, and the data was subsequently extracted. To gain insights into the evolution and dynamics of this research field, we employed bibliometric analysis tools such as the Bibliometrix R package, VOSviewer, and Microsoft Excel to visualize and analyze various dimensions, including prominent journals, leading authors, esteemed institutions, contributing countries/regions, highly cited papers, and frequently occurring keywords.; A total of 888 papers were obtained. The number of publications about GM/CC studies has increased gradually. China and the United States published the largest number of papers. The INSERM was in the leading position in publishers. The most productive authors were Zitvogel L from France. Cancers had the largest number of papers. Citation analysis explained the historical evolution and breakthroughs in GM/CC research. Highly cited papers and common keywords illustrated the status and trends of GM/CC research. Four clusters were identified, and the hot topics included the role of the GM in the efficacy and toxicity of CC, the targeting of the GM to improve the outcome of CC, the mechanism by which the GM affects CC, and the correlation of the GM with carcinogenesis and cancer therapy. Metabolism, GM-derived metabolites, tumor microenvironment, immunity, intestinal barrier, tumor microbiota and Fusobacterium nucleatum may become the new hotspots and trends of GM/CC research.; This study analyzed global publications and bibliometric characteristics of the links between GM and CC, identified highly cited papers in GM/CC, provided insight into the status, hotspots, and trends of global GM/CC research, and showed that the GM can be used to predict the efficacy and toxicity of CC and modifying the GM can improve the outcomes of chemotherapeutics, which may inform clinical researchers of future directions.; © 2024. The Author(s).",15,1,833,,Citation; China; Scholarly communication; Web of science; Library science; Citation analysis; Impact factor; Medicine; Data science; Political science; Computer science; Pathology; Meta-analysis; Publishing; Law,Bibliometrics; Cancer; Chemotherapy; Gut microbiota; Highly cited papers; Research trends,,,,,http://dx.doi.org/10.1007/s12672-024-01704-8,39715958,10.1007/s12672-024-01704-8,,PMC11666878,0,000-445-932-280-72X; 001-500-878-457-963; 004-163-504-030-732; 005-009-573-569-097; 005-989-419-562-555; 006-088-616-273-099; 006-617-709-951-54X; 006-691-066-133-644; 008-616-701-995-853; 010-305-966-410-199; 011-501-602-965-163; 011-602-840-953-478; 011-955-033-485-579; 012-998-375-223-815; 013-099-901-023-766; 013-704-800-122-020; 014-153-604-171-640; 014-238-437-616-077; 015-830-320-011-057; 016-198-890-446-79X; 020-025-894-803-896; 020-743-322-644-478; 021-538-336-083-791; 022-331-970-734-238; 022-608-530-695-641; 025-460-119-101-55X; 026-176-655-899-065; 026-205-433-219-423; 028-286-338-755-658; 028-328-842-359-067; 028-494-909-599-350; 028-884-440-441-612; 029-691-469-213-213; 029-760-680-547-418; 029-820-458-338-22X; 030-567-911-293-883; 030-672-241-297-643; 030-865-563-207-162; 031-627-388-359-806; 031-938-712-670-531; 032-102-928-574-801; 032-170-678-023-664; 032-642-982-059-840; 034-578-836-836-014; 034-819-850-185-558; 035-563-795-557-215; 036-007-409-154-258; 037-602-139-019-162; 038-181-063-178-91X; 038-309-331-366-387; 042-559-321-500-438; 042-569-999-403-913; 042-842-707-522-844; 043-359-740-462-974; 046-035-880-463-31X; 047-880-071-327-750; 049-009-570-479-949; 051-237-518-666-807; 052-271-997-920-336; 053-010-354-564-228; 054-534-914-128-234; 054-753-492-428-922; 055-231-802-631-175; 056-601-598-309-489; 059-094-215-524-460; 062-078-912-075-056; 064-542-887-581-65X; 068-718-039-722-95X; 069-166-561-577-314; 071-418-308-614-038; 075-423-442-861-058; 075-465-780-714-769; 076-106-632-124-558; 076-727-347-736-696; 081-611-032-709-913; 081-785-507-802-477; 082-546-795-973-833; 087-386-786-176-842; 087-461-409-605-338; 087-909-737-874-847; 088-240-805-623-033; 089-057-122-829-252; 090-187-335-700-074; 096-097-360-030-227; 097-111-180-840-657; 097-453-650-594-842; 101-226-012-655-885; 103-068-915-324-94X; 105-966-206-149-509; 105-997-444-736-700; 107-483-302-885-238; 107-820-481-063-663; 110-417-713-841-769; 114-648-480-868-592; 133-874-504-740-142; 137-923-160-841-612; 145-148-088-105-383; 149-070-756-054-250; 157-164-532-826-204; 157-968-568-274-804; 160-316-454-347-838; 166-625-203-804-771; 179-606-085-422-884; 186-199-021-105-490,1,true,cc-by,gold -178-695-013-154-439,Produção do Conhecimento sobre Desenvolvimento Motor e Transtorno do Espectro Autista: uma Revisão Bibliométrica,,2023,journal article,Revista Brasileira de Educação Especial,19805470; 14136538,FapUNIFESP (SciELO),Brazil,Márcia Franciele SPIES; Guilherme da Silva GASPAROTTO,"RESUMO: O Transtorno do Espectro Autista (TEA) é caracterizado por déficits nas áreas de comunicação, interação social e comportamentos restritos, estereotipados e repetitivos. Embora seja um tema em constante discussão na literatura atual, ainda existem muitas dúvidas a serem investigadas. Dessa forma, neste artigo, teve-se como objetivo investigar a produção científica sobre o desenvolvimento motor em crianças com TEA. Para tanto, realizou-se uma análise bibliométrica por meio de buscas nas bases de dados científicas Web of Science (WoS) e Scopus, para o tema desenvolvimento motor em crianças com TEA, no período compreendido entre os anos de 2014 e 2021. Para a análise de dados, foram utilizados os pacotes Bibliometrix e o Shiny UI for bibliometrix package (biblioshiny), além do software Ms Excel® 2013 para a apresentação das tabelas e dos quadros. Obteve-se um corpus de análise de 89 artigos conforme os critérios de elegibilidade. A bibliometria revelou um panorama de lacunas na área da educação, pois não foram encontradas publicações em periódicos específicos da área. Referenda-se, também, que estudos dessa natureza são importantes para identificar as tendências em relação à produção do conhecimento, a fim de mapear as instituições, os periódicos e os autores que mais publicam no mundo",29,,,,Psychology; Humanities; Physics; Philosophy,,,,,https://www.scielo.br/j/rbee/a/Z63F8GwMDH9JbmXLSXGXrNs/?lang=pt&format=pdf https://doi.org/10.1590/1980-54702023v29e0013,http://dx.doi.org/10.1590/1980-54702023v29e0013,,10.1590/1980-54702023v29e0013,,,0,000-672-819-785-187; 013-524-854-219-241; 018-815-097-327-537; 021-743-884-810-382; 024-166-789-160-651; 026-480-658-394-851; 026-882-449-325-237; 031-630-251-923-821; 045-765-782-662-161; 049-218-487-966-907; 054-110-362-093-782; 061-211-955-661-876; 072-113-815-370-911; 084-600-053-949-524; 086-225-477-237-054; 095-138-399-281-770; 102-460-932-929-123,1,true,cc-by,gold -178-748-885-430-222,Understanding the Landscape of Gig Workers' Well-Being: A Bibliometric Analysis,2024-07-23,2024,journal article,International Journal of Community Well-Being,25245295; 25245309,Springer Science and Business Media LLC,,Sapna Taneja,,7,4,617,633,Sociology; Geography,,,,Indian Council of Social Science Research,,http://dx.doi.org/10.1007/s42413-024-00226-z,,10.1007/s42413-024-00226-z,,,0,007-286-418-919-243; 012-460-135-551-962; 017-714-995-116-708; 019-873-972-148-687; 022-478-719-628-933; 023-757-988-697-193; 034-768-039-318-254; 035-141-674-042-59X; 046-992-864-415-70X; 047-134-478-431-993; 054-317-200-556-623; 064-916-137-475-413; 067-146-960-971-158; 085-394-648-196-543; 092-155-595-059-566; 094-883-897-027-656; 105-338-542-606-716; 147-113-296-105-735; 154-685-889-140-250; 178-876-898-733-616,2,false,, -178-846-153-742-342,OPORTUNIZANDO O ENSINO DA ESTATÍSTICA MEDIANTE UM PROJETO DE EXTENSÃO,,2022,journal article,Revista SODEBRAS,18093957,Revista SODEBRAS,,L. Moreira; J. F. C. Azevedo; T. R. Fontenele,"The professional nurse, when dealing with a patient, often experiences adverse situations in their work environment. This can affect their health. In order to know about this daily life, the present study aimed to carry out a bibliometric analysis on the theme Burnout in nurses where, in a more punctual way, we sought to identify the main predictors of Burnout of this profession from recent international publications. In the first part of the study, the software R (bibliometrix package) was used. Burnout predictors were identified from the articles resulting from the bibliometric search. The survey results pointed to an increase in publications over the years with a peak in 2018. The largest contributions in quantitative terms are still from the United States of America. Burnout predictors have an organizational and relational origin. Individual aspects, such as resilience, appear in a relevant way to avoid professional illness.",17,197,48,60,Physics,,,,,,http://dx.doi.org/10.29367/issn.1809-3957.17.2022.197.48,,10.29367/issn.1809-3957.17.2022.197.48,,,0,,0,true,,gold -178-920-833-351-911,THE ROLE OF CYBER SECURITY IN THE SYSTEM OF ECONOMIC SECURITY: BIBLIOMETRIC ANALYSIS,,2024,journal article,INNOVATIVE ECONOMY,23091533; 23104864,"Institute of Economics, Technologies and Entrepreneurship",,Vitaliia Koibichuk,"Purpose. The aim of the article is to conduct a bibliometric analysis to determine the role of cyber security in the system of economic security and to identify the leading scientific institutions and researchers who are engaged in this issue.; Methodology of research. The information sample of the study was obtained by a corresponding search query in the Scopus scientometric database, further analysis was carried out using the programming language R and R Studio, the Bibliometrix package and the Shiny and Bibliometrix libraries. At the first stage of the research, the Convert2df () function was used to download and convert the data, which made it possible to create a frame of bibliographic data. Then, at the second stage, the Summary () function was used to obtain general information about publications devoted to the research topic. At the third stage, using the term Extraction () function, key terms are determined from the text fields (theses, titles, author, keywords, etc.) of the bibliographic collection and a tripolar graph was formed, reflecting the relationship between the affiliations of the authors, keywords, and countries of research, and with the help of the bibliometric function H-index (), the top 10 sources of the publishing house were determined by the value of the Hirsch index. The fourth stage determines the total number of citations of journals in which scientists have published their research related to the role of cyber security in the system of economic security, using the citations () function, and the list of the most cited authors is formed using the dominance () function.; Findings. The conducted bibliometric analysis shows the high relevance of the research topic. Comparing the scientific productivity of different countries in the field of cyber security and determining its role in the system of economic security shows that the leaders are the USA, China, and India. This is due to the large investment in scientific research, the developed IT industry, the high level of cyber threats in the US, the extremely rapid development of the digital economy and the state support for research in the field of cyber security in China, the large number of IT specialists and the English-speaking environment, which promotes international cooperation in India. It should also be noted that over the past five years there has been a tendency to expand the geography of research, which indicates a growing awareness of the importance of the role of cyber security in the system of economic security.; ; Originality. It is substantiated that a complex combination of bibliometric functions – Convert2df(), Summary (), term Extraction (), H-index (), citations (), dominance () of the Bibliometrix package, which, unlike the existing manual counting of the number of citations, the number of publications and the use of traditional metrics (country, year of publication, affiliation of the author), made it possible to conduct an automated bibliometric analysis of the role of cyber security in the system of economic security, using a wide range of metrics, and to identify leading scientific institutions and researchers engaged in this issue, and to gain knowledge about the structure of the scientific community.; Practical value. The practical significance of the research results has a place for state authorities, scientific community and society. For state authorities – to strengthen the integration of cyber security into the general strategy of economic development (the results show the importance of cyber security for economic development, however, there is no clear integration of cyber security into the general strategy of economic development of countries and organizations, which leads to the disparity of efforts and the reduction of the effectiveness of investments in cyber security). For the scientific community – for identify promising areas of research, optimization of research processes and collaboration and cooperation. For society – raising awareness of the role of cyber security in the system of economic security and strengthening the protection of personal data.; Key words: cyber security, economic security of the state, digital technologies, Internet of Things, bibliometric analysis.",,,150,158,Security analysis; Computer security; Computer science,,,,,,http://dx.doi.org/10.37332/2309-1533.2024.2.19,,10.37332/2309-1533.2024.2.19,,,0,002-159-831-998-842; 013-507-404-965-47X; 031-571-099-428-801; 052-842-733-790-87X; 078-366-814-506-585,0,false,, -178-993-523-197-493,Bibliometrix research of noise removal techniques in digital images for defense,2025-04-25,2025,journal article,"International Journal of Applied Mathematics, Sciences, and Technology for National Defense",29859352; 29860776,Foundation of Advanced Education,,Fulkan Kafilah Al Husein; Muhammad Yusuf Al Habsy; Damaris Nugrahita Christi; Agnes Emanuela Hutagaol; Ahmad Kadri Bin Junoh,"In modern defense applications, the accuracy and clarity of digital images are crucial, especially for tasks like surveillance, reconnaissance, and intelligence gathering. However, noise introduced during image acquisition or transmission significantly degrades image quality. This paper presents a comprehensive review of various noise removal techniques employed in digital image processing for defense systems. The review focuses on both linear and non-linear methods, including matrix decomposition, hybrid deep learning, Generative Adversarial Networks (GANs), and trimming filters. Emphasis is placed on the effectiveness of each technique in enhancing image quality while preserving critical details. The use of linear and non-linear methods such as deep learning-based approaches is shown to outperform traditional linear filters in handling complex noise patterns, particularly in scenarios requiring precise object detection and image restoration. The paper highlights a comprehensive overview of the researched literature and shows the latest trends and developments in the field. Finally, recommendations for future research and the development of more robust noise reduction methods are provided, aiming to improve operational effectiveness in defense applications.",3,1,9,24,Noise (video); Computer science; Environmental science; Artificial intelligence; Image (mathematics),,,,,,http://dx.doi.org/10.58524/app.sci.def.v3i1.463,,10.58524/app.sci.def.v3i1.463,,,0,,0,true,cc-by-sa,gold -179-320-612-783-806,Global Research Progress on Land Application of Sewage Sludge: A Comprehensive Bibliometric Review,2025-05-03,2025,journal article,Waste and Biomass Valorization,18772641; 1877265x,Springer Science and Business Media LLC,Germany,Zhonghong Li,,,,,,Environmental science; Sewage sludge; Waste management; Environmental planning; Sewage; Engineering; Environmental resource management; Environmental engineering,,,,,,http://dx.doi.org/10.1007/s12649-025-03084-8,,10.1007/s12649-025-03084-8,,,0,000-408-248-343-234; 000-997-626-270-449; 002-052-422-936-00X; 002-215-101-749-418; 005-149-821-562-156; 006-409-871-206-920; 008-570-020-700-377; 008-774-174-405-244; 011-141-830-200-510; 011-591-600-223-31X; 012-011-772-179-055; 013-355-397-161-819; 013-507-404-965-47X; 014-024-762-505-748; 014-229-482-833-017; 014-383-115-221-073; 014-722-813-847-86X; 015-792-214-822-53X; 017-789-484-384-926; 017-840-670-617-704; 019-655-298-458-214; 020-598-191-305-645; 021-108-139-916-512; 021-181-519-274-655; 021-550-117-691-473; 025-350-187-624-531; 025-357-778-836-36X; 026-871-295-697-439; 028-880-462-188-576; 028-937-128-182-077; 030-612-148-935-036; 030-744-880-055-974; 030-907-126-179-530; 032-750-284-725-576; 032-764-461-790-326; 037-134-258-995-057; 037-332-920-647-637; 042-762-760-701-753; 046-093-996-281-679; 047-193-169-858-58X; 048-607-202-817-821; 049-203-966-354-412; 049-964-103-951-699; 051-155-172-617-338; 054-652-051-695-440; 055-047-345-899-482; 055-104-368-814-38X; 055-838-098-560-799; 063-013-116-098-897; 064-400-499-357-900; 066-512-216-655-094; 066-615-742-360-650; 069-839-197-353-405; 072-287-553-675-167; 075-111-332-597-740; 076-817-894-863-255; 078-196-335-144-186; 081-364-390-950-090; 083-244-356-706-066; 083-575-766-136-971; 088-592-388-928-010; 091-050-489-858-308; 091-363-532-710-569; 092-633-738-676-275; 096-027-965-411-838; 099-735-437-510-61X; 104-519-078-998-352; 106-936-985-189-882; 107-827-151-149-669; 108-035-543-843-968; 109-395-420-317-891; 113-312-530-811-776; 114-068-125-475-54X; 114-362-009-233-831; 117-046-387-137-366; 117-904-481-275-51X; 120-868-280-130-544; 125-211-615-946-074; 128-006-438-606-832; 128-820-175-560-364; 129-852-991-172-493; 130-365-814-074-937; 139-750-660-829-927; 140-584-813-681-05X; 142-506-921-841-46X; 150-189-216-770-663; 156-131-505-006-123; 161-602-508-640-559; 162-099-589-895-182; 163-097-275-114-619; 164-887-006-332-864; 165-367-977-989-065; 166-003-549-649-477; 172-266-140-240-002; 177-373-791-112-819; 183-985-001-161-89X; 198-250-286-865-520,0,false,, -179-336-139-537-672,Regulatory Advances and Emerging Challenges in Occupational Health and Safety: A Bibliometric Analysis,2025-06-17,2025,journal article,Minerva,26973650,AutanaBooks S.A.S,,Katia Ivonne Larrea Barrueto,"A bibliometric review on the evolution of research in occupational safety and health using the Scopus database is presented. 118 publications from the last 10 years were analyzed, identifying an average annual growth of 2.81% in scientific production. The review used Rstudio's Bibliometrix tool to explore keywords, co-authorships, and emerging themes. The results highlight the centrality of topics such as legislation, prevention and promotion of occupational health, while concepts such as artificial intelligence and the impact of the COVID-19 pandemic emerge as for future research. The findings underscore the need for more robust and adaptive regulatory frameworks to improve workplace safety and address gaps in developing countries.",6,17,104,115,,,,,,,http://dx.doi.org/10.47460/minerva.v6i17.199,,10.47460/minerva.v6i17.199,,,0,,0,false,, -179-543-866-290-970,Education and Business in Conditions of Coopetition: Bibliometrics,,2022,journal article,Business Ethics and Leadership,25206311; 25206761,Academic Research and Publishing U.G.,,Vitaliia Koibichuk; Anastasiia Samoilikova; Valeriia Herasymenko,"The study of the relationship between education and business is a very relevant issue when education and business are key factors in developing and uplifting the economy. Education is the foundation for creating a business since the effective activity is impossible without a strong information base. The purpose of this research is a bibliographic review of scientific publications devoted to the relationship between business and education, based on materials indexed by the Scopus, Web of Science, and Mendeley databases using the built-in functions of the Bibliometrix application and the R programming language. The logic of the research is implemented with the help of three stages: at the first stage, an analysis of literary sources related to bibliometric analysis, as well as about business and education, the interdependence of education and business, which were published in the publishing house of MDPI scientific journals with open access, was carried out. Survey and interview methods are the methodological tools of most of the analyzed publications in the open access of the MDPI database. The research is conducted in the R language, using VOSViewer tools for bibliometric analysis. Various qualitative and quantitative methods were used to analyze the relationship between education and business, such as performance analysis, scientific mapping and thematic analysis, structural equation modelling, and Z-score statistics. At the second stage, the main functions of the Bibliometrix package were studied, countries, keywords constructed a three-field plot, and the year of publication of cited references to reflect the proportion of research topics for each country and the freshness of cited articles. Source clustering through Bradford’s Law was also used to identify the best journals for publishing own research and searching for the most relevant scientific information. In addition, the Hirsch and Gini indexes of the selected sample of publications were examined in detail within the second stage. The Hirsch index is a quantitative measure of productivity based on analyzing published publications and citations. The distribution of authorship is estimated using the Gini index. At the third stage, keywords were analyzed, and a table was built with the most frequently used words to decrease the number of keywords mentioned. The conducted comprehensive analysis of scientific publications confirmed the close correlation of paradigms of business and education in the conditions of coopetition in modernity.",6,4,49,60,Scopus; Computer science; Field (mathematics); Bibliometrics; Publishing; Knowledge management; Data science; Library science; Political science; Mathematics; MEDLINE; Pure mathematics; Law,,,,,https://armgpublishing.com/wp-content/uploads/2023/01/BEL_4_2022_5.pdf https://doi.org/10.21272/10.21272/bel.6(4).49-60.2022,http://dx.doi.org/10.21272/10.21272/bel.6(4).49-60.2022,,10.21272/10.21272/bel.6(4).49-60.2022,,,0,002-592-665-696-765; 007-206-754-521-813; 013-507-404-965-47X; 020-196-220-205-001; 086-841-776-723-721; 087-698-591-446-382; 088-577-115-503-054; 107-549-688-291-73X; 111-088-248-024-721; 132-116-966-608-382; 146-568-411-116-662; 170-195-756-439-943; 183-791-301-288-918,1,true,cc-by,gold -180-050-362-798-236,Management Control System and Organization: A Bibliometrix Approach Analysis,,2023,conference proceedings article,"Proceedings of the International Conference on Sustainability in Technological, Environmental, Law, Management, Social and Economic Matters, ICOSTELM 2022, 4-5 November 2022, Bandar Lampung, Indonesia",,EAI,,Susanto Wibowo; Agus Ismaya; Helmi Yazid; Dadan Ramdhani,This research is to see an overview of the management control system (MCS) associated with the organization using a bibliometrix analysis approach. The research method used is bibliometrix analysis approach using Vosviewer and Publish or Perish software. The total sample data observed from Scopus so,,,,,Publish or perish; Computer science; Scopus; Sample (material); Control (management); Publication; Knowledge management; Data science; Artificial intelligence; Publishing; Chemistry; MEDLINE; Chromatography; Political science; Advertising; Law; Business,,,,,http://eudl.eu/pdf/10.4108/eai.4-11-2022.2328757 https://doi.org/10.4108/eai.4-11-2022.2328757,http://dx.doi.org/10.4108/eai.4-11-2022.2328757,,10.4108/eai.4-11-2022.2328757,,,0,,0,true,,bronze -180-206-353-599-057,Trends and Perspectives on Tax Benefits Research,2024-10-29,2024,book chapter,Advances in Public Policy and Administration,24756644; 24756652,IGI Global,,Carlos Lucas; Sérgio Ravara Cruz; Cecília Rendeiro Carmo,"Reducing taxation is a relevant and cross-cutting issue in society, at the level of governments, companies and citizens. There are currently a large number of scientific publications on this subject. The aim of this study is to present a mapping of scientific production on the subject of tax benefits, which will make it possible to understand the evolution and trends of research in this area. A bibliometric analysis was carried out using the Bibliometrix tool, based on the documents available on the Scopus and Web of Science platforms. The results show that the greatest growth in research on this topic has occurred from the beginning of this century to the present day. The use of dominant expressions is also observed, resulting in two clusters that separate research into tax benefits at a company level from those at an individual level. This result suggests the need for future studies to deal separately with corporate and personal tax benefits.",,,473,514,,,,,,,http://dx.doi.org/10.4018/979-8-3693-3908-4.ch017,,10.4018/979-8-3693-3908-4.ch017,,,0,001-981-573-598-52X; 002-355-207-477-726; 004-203-631-576-272; 007-180-432-016-459; 009-386-536-900-587; 012-746-291-222-558; 013-507-404-965-47X; 015-511-075-443-666; 016-365-444-233-984; 016-731-630-980-120; 017-012-914-191-524; 021-758-257-383-563; 024-485-942-413-984; 024-491-347-287-793; 028-495-369-487-554; 032-747-714-939-631; 034-658-158-500-326; 034-768-039-318-254; 046-992-864-415-70X; 049-001-576-519-853; 050-609-067-982-963; 054-006-295-200-348; 057-790-386-663-285; 059-955-457-171-364; 062-255-433-483-145; 062-903-056-622-033; 064-168-335-161-967; 066-494-641-469-00X; 071-217-751-444-52X; 077-222-224-487-717; 078-221-187-990-808; 083-979-089-006-117; 092-512-273-988-218; 098-205-988-700-140; 099-316-007-966-979; 101-752-490-869-458; 102-487-708-741-759; 104-227-856-923-759; 104-812-305-561-330; 108-324-985-013-153; 110-454-625-388-629; 120-211-050-313-621; 128-964-697-180-29X; 131-827-417-907-683; 134-366-982-952-006; 137-768-582-099-545; 142-485-180-231-276; 143-224-855-790-385; 153-653-915-439-385; 156-313-339-981-00X; 162-008-288-576-034; 163-208-488-272-986; 175-019-538-535-08X; 177-727-794-241-806; 178-372-257-351-133; 183-847-505-313-097; 199-035-310-817-065,0,false,, -180-389-715-225-701,Preprocesamiento de publicaciones acerca de indentidad digital descentralizada y autgobernada.,2022-01-01,2022,dataset,Figshare,,,,Roberto Pava,Referencias en formato bibtex obtenidas de las bases de datos Scopus y WoS. Preprocesamiento con el paquete bibliometrix,,,,,Psychology; Philosophy,,,,,https://figshare.com/articles/dataset/Referencias_sobre_SSI_obtenidas_en_formato_bibtex/19579492/2,http://dx.doi.org/10.6084/m9.figshare.19579492.v2,,10.6084/m9.figshare.19579492.v2,,,0,,0,true,cc-by,gold -180-612-798-487-350,Interdependence between supply chains and sustainable development: global insights from a systematic review,2024-05-22,2024,journal article,Review of Managerial Science,18636683; 18636691,Springer Science and Business Media LLC,Germany,Allan Dênisson Soares da Silva; Wesley Vieira da Silva; Luciana Santos Costa Vieira da Silva; Nicholas Joseph Tavares da Cruz; Zhaohui Su; Claudimar Pereira da Veiga,,19,3,931,962,Supply chain; Sustainable development; Business; Economics; Biology; Ecology; Marketing,,,,Conselho Nacional de Desenvolvimento Científico e Tecnológico; Conselho Nacional de Desenvolvimento Científico e Tecnológico,,http://dx.doi.org/10.1007/s11846-024-00770-0,,10.1007/s11846-024-00770-0,,,0,000-209-413-168-336; 000-321-618-347-08X; 000-531-135-885-460; 001-155-836-460-086; 002-042-967-198-757; 002-304-896-362-755; 002-888-590-273-743; 004-390-094-341-449; 006-114-640-295-729; 007-119-124-971-750; 008-146-495-921-306; 009-897-352-900-368; 010-021-078-612-230; 010-326-684-892-284; 011-717-522-511-64X; 011-969-464-045-345; 013-507-404-965-47X; 013-575-596-952-685; 013-741-859-762-80X; 014-649-409-691-72X; 015-319-950-831-465; 017-137-381-772-332; 017-481-567-160-10X; 017-739-621-897-141; 020-405-480-224-004; 021-965-638-332-93X; 022-902-654-665-02X; 023-901-293-482-245; 023-959-996-735-941; 024-975-377-719-658; 026-110-771-860-609; 027-027-875-347-016; 027-428-668-264-186; 029-320-868-096-162; 029-621-942-425-403; 034-904-395-190-721; 035-308-923-528-438; 036-275-446-445-653; 037-298-237-320-06X; 039-205-076-326-504; 040-554-379-761-723; 042-959-583-991-751; 043-296-182-294-930; 044-354-597-287-934; 045-249-612-521-795; 045-621-536-054-707; 045-893-356-732-602; 050-514-269-290-357; 051-647-739-244-271; 054-046-934-960-770; 055-666-469-824-784; 056-691-571-404-744; 060-225-652-302-332; 062-448-532-452-214; 064-915-408-087-128; 065-043-321-803-292; 065-176-911-622-239; 065-938-920-110-671; 068-348-198-363-629; 069-338-953-456-237; 069-772-798-971-109; 070-601-413-139-768; 070-640-640-030-318; 071-736-631-283-842; 073-236-513-589-340; 075-495-006-421-497; 080-092-300-294-622; 080-359-608-721-491; 080-493-122-705-958; 080-715-906-599-162; 082-331-907-005-063; 082-723-692-096-334; 082-862-223-968-339; 083-137-544-456-89X; 085-008-355-027-051; 085-044-141-144-824; 085-300-287-100-525; 087-446-838-596-390; 097-245-926-238-00X; 098-148-901-345-935; 098-797-592-281-826; 100-603-573-401-580; 101-197-773-835-274; 107-777-651-434-586; 110-015-506-057-371; 113-682-442-621-962; 120-975-417-040-341; 130-538-318-080-038; 136-301-308-546-327; 136-341-354-859-11X; 139-561-127-752-770; 142-599-376-795-933; 147-900-001-588-622; 152-705-589-629-84X; 154-454-690-344-223; 163-062-755-592-644; 164-102-798-131-493; 169-957-326-836-810; 177-954-564-749-452; 186-820-274-106-574; 189-466-455-736-057,3,false,, -180-707-997-804-330,A user-friendly method to merge Scopus and Web of Science data during bibliometric analysis,2021-10-22,2021,,,,,,Andrea Caputo; Mariya Kargina,"Bibliometric studies in management and related fields are growing exponentially due to the need to systematize and summarize the growing body of publications. To do so, scholars mostly retrieve publications and metadata from either Scopus or Web of Science. Only a few bibliometric studies merge the two databases to conduct a single integrated analysis. Recent studies demonstrated the benefits of merging data from Scopus and Web of Science and presented methods for the merging. In this paper we build upon a recent method to simplify some of the key steps of merging datasets when using the R package Bibliometrix to perform bibliometric analyses. The result is a user friendly, accessible, three-step method that allows researchers to save time without compromising the integrity of the data, and the analysis. Our method is particularly beneficial for a wider application as it does not require coding skills, and neither proprietary nor shareware software.",,,1,7,Coding (social sciences); Merge (version control); Key (cryptography); Information retrieval; Software; Web of science; Computer science; User Friendly; Scopus; Metadata,,,,,https://link.springer.com/article/10.1057%2Fs41270-021-00142-7 https://eprints.lincoln.ac.uk/id/eprint/45860/,https://link.springer.com/article/10.1057%2Fs41270-021-00142-7,,,3210837814,,0,001-153-564-508-98X; 002-052-422-936-00X; 002-889-632-858-980; 005-676-355-691-042; 005-688-363-332-013; 008-146-495-921-306; 010-442-924-794-711; 013-507-404-965-47X; 017-300-737-144-757; 017-750-600-412-958; 020-769-541-764-758; 022-050-154-142-786; 026-125-810-364-184; 027-845-295-187-970; 041-910-360-555-238; 045-422-273-148-899; 045-797-416-772-535; 052-872-010-507-265; 067-461-470-339-184; 068-970-970-192-264; 069-764-890-140-842; 070-212-018-137-202; 070-665-150-453-490; 072-856-861-900-730; 080-688-314-803-632; 083-233-429-885-517; 083-275-795-865-394; 085-300-287-100-525; 116-194-587-286-735; 123-202-581-406-928; 141-026-656-461-626; 158-253-621-523-361; 195-638-802-395-994,0,false,, -180-814-638-298-660,Bibliometric and review analysis of argan trees studies: global research trends and challenges,2025-06-09,2025,journal article,Agroforestry Systems,01674366; 15729680,Springer Science and Business Media LLC,Netherlands,El Houcine El Moussaoui; Aicha Moumni; Saïd Khabba; Salah Er-Raki; Bouchra Ait Hssaine; Abdelghani Chehbouni; Abderrahman Lahrouni,,99,5,,,,,,,,,http://dx.doi.org/10.1007/s10457-025-01228-2,,10.1007/s10457-025-01228-2,,,0,000-156-949-284-70X; 003-742-774-056-14X; 004-261-747-900-72X; 004-442-272-827-479; 004-888-017-198-085; 006-486-933-020-38X; 010-286-138-242-213; 010-528-302-563-465; 011-771-786-492-697; 011-805-146-484-114; 013-101-146-378-482; 015-834-674-208-373; 016-788-479-766-398; 017-231-266-721-389; 018-305-172-166-13X; 019-696-069-676-331; 020-709-222-760-261; 023-361-339-523-766; 023-675-542-492-16X; 025-624-887-926-659; 025-722-568-071-613; 025-824-143-908-307; 026-521-813-196-950; 027-762-493-711-338; 029-365-930-889-999; 032-319-343-710-510; 032-811-623-336-935; 033-344-244-760-02X; 033-424-556-032-97X; 033-676-000-213-928; 034-759-428-236-389; 034-768-039-318-254; 036-578-300-424-313; 040-920-198-600-987; 043-415-644-775-579; 044-362-590-043-689; 044-694-390-657-724; 045-840-762-993-104; 045-998-659-959-813; 046-512-643-685-700; 048-795-598-174-535; 051-757-949-274-96X; 053-128-462-684-490; 055-949-188-699-753; 056-020-504-866-415; 056-168-375-396-285; 056-434-333-608-509; 064-660-806-366-18X; 065-120-317-811-966; 065-728-938-401-279; 065-793-531-089-085; 067-989-069-293-365; 071-437-796-984-313; 072-828-219-963-082; 074-516-366-256-783; 076-369-750-156-379; 076-906-946-336-997; 092-923-386-804-872; 093-396-223-350-639; 094-278-959-353-065; 094-761-876-559-359; 095-034-504-033-116; 096-506-762-173-161; 098-253-540-747-633; 100-383-921-221-892; 104-847-313-427-369; 107-592-737-909-14X; 110-674-034-191-36X; 112-639-584-903-674; 115-744-018-686-250; 116-332-464-344-977; 123-455-795-200-63X; 124-989-585-622-271; 128-852-545-547-690; 134-946-296-711-668; 138-118-583-500-179; 142-618-452-891-830; 144-126-839-725-142; 156-002-038-200-670; 156-926-426-916-005; 171-893-862-996-270; 177-165-536-084-682; 181-404-229-991-434; 182-154-075-554-473; 184-519-570-492-339; 185-418-881-859-031; 188-051-313-874-04X; 188-698-862-976-572; 189-521-513-557-508; 189-546-702-683-985,0,false,, -180-873-037-005-236,Health and Urbanism: General Statistics in Literature and Research Trends,,2022,journal article,International Journal of Innovative Studies in Sociology and Humanities,24564931,ARC Publications,,Nassima Khenchouche; Labii Belkacem; Amel Benzaoui,"This research aims to determine the overall trend in the subject, the core publications, the significant subjects, and the ongoing research thematic.Data preprocessing was conducted in order to match the data with the Bibliometrix utility suite's criteria. METHODOLOGYThe methodology is based on the documents extracted from Scopus platform, and the most relevant statistics are shown in Table 1.The main steps are as follow:",7,7,25,29,Urbanism; Regional science; Geography; Health statistics; Statistics; Sociology; Demography; Mathematics; Archaeology; Population; Architecture,,,,,,http://dx.doi.org/10.20431/2456-4931.070703,,10.20431/2456-4931.070703,,,0,,0,true,,bronze -181-008-368-077-082,Bibliometric - thematic analysis and a technology-enabler-barrier-based framework for digital supply chain,,2023,journal article,International Journal of Value Chain Management,17415357; 17415365,Inderscience Publishers,United Kingdom,Vikrant Sharma; Satyajit Anand; Mukesh Kumar; Manjula Pattnaik,"Digital supply chain is a proactive, value-driven, and efficient process that helps businesses generate new sources of revenue and business value. From 2000 to 2021, this article covers the evolution of digital supply chain research, outlining critical concerns and trends for the future. This analysis aims to undertake a bibliometric analysis of the literature on digital supply chains to identify emerging trends in this subject through a review of the most influential articles, keywords, authors, institutions and countries. Three software tools were used to accomplish this goal: the R package (Bibliometrix R Package), VOSviewer and SciMAT. According to the research, Germany, Turkey, and the USA have the most publications and total citations. Additionally, a framework based on technology, enablers, and barriers is proposed, and a discussion of the future path of the digital supply chain. This study is the first to analyse digital supply chains' evaluation and give a decision-making framework.",14,1,34,34,Enabling; Supply chain; Value chain; Revenue; Business; Supply chain management; Process management; Computer science; Knowledge management; Marketing; Accounting; Psychology; Psychotherapist,,,,,,http://dx.doi.org/10.1504/ijvcm.2023.129268,,10.1504/ijvcm.2023.129268,,,0,,6,false,, -181-108-226-468-537,Bibliometric analysis and description of research trends on transforaminal full-endoscopic approach on the spine for the last two-decades.,2023-03-27,2023,journal article,"European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society",14320932; 09406719,Springer Science and Business Media LLC,Germany,Yanting Liu; Khanathip Jitpakdee; Facundo Van Isseldyk; Jung Hoon Kim; Young Jin Kim; Kuo-Tai Chen; Kyung-Chul Choi; Gun Choi; Junseok Bae; Javier Quillo-Olvera; Cristian Correa; Marlon Sudario Silva; Vit Kotheeranurak; Jin-Sung Kim,,32,8,2647,2661,Medicine; Bibliometrics; Index (typography); Web of science; Quality (philosophy); Library science; Subject (documents); China; Productivity; Geography; Economic growth; Computer science; Internal medicine; Archaeology; Philosophy; Meta-analysis; Epistemology; World Wide Web; Economics,Bibliometrix; Citation analysis; CiteSpace; Full endoscopy; Spine; Transforaminal; VOSviewer,Humans; Bibliometrics; China; Endoscopy; Republic of Korea; Spine/surgery,,Ministry of Health and Welfare,,http://dx.doi.org/10.1007/s00586-023-07661-0,36973463,10.1007/s00586-023-07661-0,,,0,000-372-361-102-115; 002-052-422-936-00X; 004-504-686-463-266; 004-773-165-121-389; 009-273-199-337-12X; 013-507-404-965-47X; 014-236-927-505-581; 014-517-987-675-428; 015-170-197-567-12X; 016-573-749-416-42X; 024-319-795-736-80X; 025-055-456-938-175; 033-767-595-888-281; 037-799-460-484-855; 042-757-913-362-347; 044-611-870-555-413; 046-563-048-702-764; 054-642-296-857-373; 054-813-933-707-700; 056-253-828-929-571; 057-110-398-686-829; 058-003-960-122-397; 064-400-499-357-900; 065-010-405-236-060; 067-950-630-471-369; 074-689-637-760-304; 076-135-472-296-002; 083-663-591-620-12X; 087-396-472-319-184; 089-472-008-306-501; 089-976-667-759-511; 097-117-383-639-643; 105-529-181-054-822; 105-682-965-743-045; 118-530-724-726-200; 169-861-011-876-811; 175-149-280-691-311; 199-965-891-598-534,7,false,, -181-404-813-659-123,Artificial intelligence-assisted multimodal imaging for the clinical applications of breast cancer: a bibliometric analysis.,2025-04-16,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Chenke Hou; Ting Huang; Keke Hu; Zhifeng Ye; Junhua Guo; Heran Zhou,"Breast cancer (BC) remains a leading cause of cancer-related mortality among women globally, with increasing incidence rates posing significant public health challenges. Recent advancements in artificial intelligence (AI) have revolutionized medical imaging, particularly in enhancing diagnostic accuracy and prognostic capabilities for BC. While multimodal imaging combined with AI has shown remarkable potential, a comprehensive analysis is needed to synthesize current research and identify emerging trends and hotspots in AI-assisted multimodal imaging for BC.; This study analyzed literature on AI-assisted multimodal imaging in BC from January 2010 to November 2024 in Web of Science Core Collection (WoSCC). Bibliometric and visualization tools, including VOSviewer, CiteSpace, and the Bibliometrix R package, were employed to assess countries, institutions, authors, journals, and keywords.; A total of 80 publications were included, revealing a steady increase in annual publications and citations, with a notable surge post-2021. China led in productivity and citations, while Germany exhibited the highest citation average. The United States demonstrated the strongest international collaboration. The most productive institution and author are Radboud University Nijmegen and Xi, Xiaoming. Publications were predominantly published in Computerized Medical Imaging and Graphics, with Qian, XJ's 2021 study on BC risk prediction under deep learning frameworks being the most influential. Keyword analysis highlighted themes such as ""breast cancer"", ""classification"", and ""deep learning"".; AI-assisted multimodal imaging has significantly advanced BC diagnosis and management, with promising future developments. This study offers researchers a comprehensive overview of current frameworks and emerging research directions. Future efforts are expected to focus on improving diagnostic precision and refining therapeutic strategies through optimized imaging techniques and AI algorithms, emphasizing international collaboration to drive innovation and clinical translation.; © 2025. The Author(s).",16,1,537,,Breast cancer; Cancer; Artificial intelligence; Medical physics; Medicine; Computer science; Data science; Internal medicine,Artificial intelligence; Bibliometric analysis; Breast cancer; Multimodal imaging,,,the Construction Fund of Medical Key Disciplines of Hangzhou (2020SJZDXK004); the Construction Fund of Medical Key Disciplines of Hangzhou (2020SJZDXK004); the Construction Fund of Medical Key Disciplines of Hangzhou (2020SJZDXK004); the Construction Fund of Medical Key Disciplines of Hangzhou (2020SJZDXK004); the Construction Fund of Medical Key Disciplines of Hangzhou (2020SJZDXK004); the Construction Fund of Medical Key Disciplines of Hangzhou (2020SJZDXK004),,http://dx.doi.org/10.1007/s12672-025-02329-1,40237900,10.1007/s12672-025-02329-1,,PMC12003249,0,002-052-422-936-00X; 005-482-910-898-996; 006-351-772-268-027; 010-881-186-573-195; 015-108-543-842-327; 015-886-672-609-16X; 016-851-351-677-029; 019-128-299-119-244; 023-020-386-258-621; 029-282-134-866-020; 029-783-712-185-880; 032-909-218-725-377; 033-427-994-245-493; 033-599-333-093-040; 036-656-168-693-890; 036-871-634-296-06X; 037-228-707-612-11X; 045-993-333-977-461; 049-391-379-302-694; 050-609-067-982-963; 052-322-664-215-986; 053-446-472-929-408; 061-744-695-481-132; 066-325-734-286-90X; 069-468-311-676-911; 072-804-479-441-647; 078-844-256-606-71X; 080-118-387-618-96X; 080-977-108-232-315; 085-702-879-395-293; 091-523-701-057-952; 092-062-550-269-321; 100-833-962-128-85X; 101-356-361-749-383; 102-172-293-181-043; 102-442-469-185-038; 105-368-945-536-801; 105-557-995-379-413; 107-483-302-885-238; 114-628-925-138-130; 115-696-626-458-928; 116-339-119-777-116; 120-670-493-162-706; 127-943-794-301-912; 132-991-403-786-471; 154-157-606-700-045; 155-488-737-392-612; 160-479-894-347-686; 168-773-357-592-465; 183-586-269-553-466; 193-231-160-845-756,0,true,cc-by,gold -181-450-613-379-511,Entity linking systems for literature reviews,2022-06-28,2022,journal article,Scientometrics,01389130; 15882861,Springer Science and Business Media LLC,Hungary,Mauricio Marrone; Sascha Lemke; Lutz M. Kolbe,"AbstractComputer-assisted methods and tools can help researchers automate the coding process of literature reviews and accelerate the literature review process. However, existing approaches for coding textual data do not account for lexical ambiguity; that is, instances in which individual words have multiple meanings. To counter this, we developed a method to conduct rapid and comprehensive analyses of diverse literature types. Our method uses entity linking and keyword analysis and is embedded into a literature review framework. Next, we apply the framework to review the literature on digital disruption and digital transformation. We outline the method’s advantages and its applicability to any research topic.",127,7,3857,3878,Computer science; Ambiguity; Coding (social sciences); Process (computing); Data science; Information retrieval; Sociology; Programming language; Social science,,,,Macquarie University,https://link.springer.com/content/pdf/10.1007/s11192-022-04423-5.pdf https://doi.org/10.1007/s11192-022-04423-5,http://dx.doi.org/10.1007/s11192-022-04423-5,,10.1007/s11192-022-04423-5,,,0,000-229-074-431-336; 002-654-784-560-503; 002-935-804-882-456; 003-839-113-220-396; 005-460-370-362-498; 005-667-160-780-884; 005-827-569-477-434; 006-509-222-574-780; 007-475-955-444-16X; 007-731-558-637-312; 009-286-240-384-618; 009-328-955-533-763; 009-449-071-775-901; 011-160-023-345-725; 011-301-822-302-672; 011-327-690-020-408; 013-507-404-965-47X; 014-099-685-907-853; 017-191-168-410-33X; 017-750-600-412-958; 017-973-530-603-086; 019-404-743-462-371; 020-772-488-180-055; 024-996-558-251-76X; 025-324-380-630-299; 025-759-850-054-154; 027-244-468-574-212; 028-470-487-668-283; 028-570-190-453-802; 029-725-111-315-779; 030-431-972-568-980; 034-207-794-611-075; 037-214-024-884-995; 037-550-015-414-716; 037-839-394-830-96X; 040-649-033-597-972; 046-261-705-342-049; 047-826-616-531-325; 048-242-887-962-976; 052-337-575-413-771; 058-874-413-569-783; 062-717-033-967-38X; 063-364-361-092-75X; 064-393-868-122-662; 069-712-527-051-47X; 070-704-403-953-071; 074-304-294-839-28X; 074-776-124-085-759; 076-952-410-942-750; 081-282-094-792-367; 082-274-674-860-502; 084-901-951-199-461; 091-271-868-270-052; 098-181-571-121-617; 099-832-315-326-27X; 100-445-029-445-191; 109-910-705-134-857; 118-936-568-081-016; 128-238-729-567-979; 128-646-777-458-294; 137-763-030-823-395; 140-467-196-238-825; 146-766-560-240-082; 147-376-549-088-975; 150-606-449-371-115; 151-276-401-580-230; 155-623-567-753-073; 161-296-155-169-999; 167-491-434-600-982; 178-406-747-015-637,6,true,cc-by,hybrid -181-910-954-970-742,A Bibliometric Analysis on Inventory Management: on a Time Horizon 2000-2022,2023-05-08,2023,conference proceedings article,Proceedings of the International Conference on Industrial Engineering and Operations Management,,IEOM Society International,,Germán Herrera Vidal; Camilo Molina Guerrero,"Inventory management is an important process in which companies plan, organize and control the goods produced, based on techniques and tools such as demand analysis and production planning and control.This article presents a bibliometric analysis based on inventory management.The proposed methodology is based on the information obtained from Scopus databases, raises and provides answers to six (6) questions, through a descriptive, thematic, collaborative and interrelated analysis, using computer supports such as VosViewers and Bibliometrix -Biblioshiny.The findings identified a positive trend in the volume of annual publications, highlighting the interest of the scientific and academic community in this area of knowledge.The results also allowed the identification of relevant topics grouped by cluster and the future research perspective, oriented to the solution of problems framed in modeling, stochastic process analysis, application of metaheristical algorithms and product design.",,,,,Computer science,,,,,https://ieomsociety.org/proceedings/2023peru/158.pdf https://doi.org/10.46254/sa04.20230158,http://dx.doi.org/10.46254/sa04.20230158,,10.46254/sa04.20230158,,,0,,0,true,,bronze -182-051-884-137-985,Advancements and trends in cooperative economy research - A Knowledge Map analysis based on CiteSpace and Bibliometrix.,2024-12-11,2024,journal article,Heliyon,24058440,Elsevier BV,Netherlands,Cong Xu; Feng Wu; Yie-Ru Chiu,"Given the rapid development and widespread application of the cooperative economy, an in-depth understanding and continuous focus on its research has become necessary. This study utilizes bibliometric analysis tools, CiteSpace and Bibliometrix, along with visualization techniques, to systematically analyze the progression and trends in cooperative economy research. Each of these tools has its unique advantages and functionalities that supplement each other in the application of bibliometric analysis, enhancing the comprehensiveness and effectiveness of the research. The aim of this study is to reveal the core themes, knowledge structure, and academic influence of cooperative economy research, providing valuable insights and references for future studies. Furthermore, this study explores the application and combination of CiteSpace and Bibliometrix in bibliometric analysis, offering a new perspective for research methodology. The findings are anticipated to contribute to the further development of cooperative economy research, providing theoretical and practical references for the sustainable development of society and economy.",11,1,e41095,e41095,Bibliometrics; Regional science; Data science; Library science; Geography; Economic geography; Computer science,Bibliometrics; Bibliometrix; CiteSpace; Cooperative economy,,,,,http://dx.doi.org/10.1016/j.heliyon.2024.e41095,39758418,10.1016/j.heliyon.2024.e41095,,PMC11699431,0,000-382-740-520-260; 001-564-492-994-494; 003-175-472-869-171; 004-852-443-590-173; 008-290-868-394-067; 013-507-404-965-47X; 013-804-365-658-717; 014-059-485-782-893; 014-672-508-469-302; 020-411-096-433-89X; 021-420-903-450-022; 026-610-713-604-536; 028-405-228-114-357; 029-575-024-606-278; 030-084-857-782-304; 035-795-351-784-233; 042-228-490-689-212; 046-617-266-044-297; 046-916-864-122-531; 046-981-842-053-02X; 046-992-864-415-70X; 048-291-625-347-755; 049-936-210-661-330; 050-896-583-688-642; 051-642-867-909-503; 052-891-316-057-520; 052-916-152-894-362; 055-070-550-438-664; 055-205-049-658-44X; 063-989-010-982-849; 065-655-063-520-456; 068-788-865-930-48X; 072-100-678-928-970; 074-707-731-021-678; 079-679-789-158-219; 083-532-857-270-885; 088-131-242-475-109; 089-954-341-474-826; 090-874-669-983-03X; 094-090-584-499-839; 098-591-397-435-144; 101-752-490-869-458; 106-364-060-601-66X; 112-712-114-926-554; 113-498-299-775-482; 115-449-831-449-379; 115-757-753-194-159; 117-899-090-355-076; 125-585-773-994-06X; 126-329-793-053-463; 131-447-102-842-26X; 132-951-028-361-837; 154-535-414-802-675; 159-105-594-520-262; 160-911-729-750-48X; 167-372-833-771-410; 174-018-440-952-095,2,true,"CC BY, CC BY-NC-ND",gold -182-199-134-307-835,Research in eating disorders: the misunderstanding of supposing serious mental illnesses as a niche specialty.,2022-09-09,2022,journal article,Eating and weight disorders : EWD,15901262; 11244909,Springer Science and Business Media LLC,Italy,Enrica Marzola; Matteo Panero; Paola Longo; Matteo Martini; Fernando Fernàndez-Aranda; Walter H Kaye; Giovanni Abbate-Daga,"Eating disorders (EDs) are mental illnesses with severe consequences and high mortality rates. Notwithstanding, EDs are considered a niche specialty making it often difficult for researchers to publish in high-impact journals. Subsequently, research on EDs receives less funding than other fields of psychiatry potentially slowing treatment progress. This study aimed to compare research vitality between EDs and schizophrenia focusing on: number and type of publications; top-cited articles; geographical distribution of top-ten publishing countries; journal distribution of scientific production as measured by bibliometric analysis; funded research and collaborations.; We used the Scopus database, then we adopted the Bibliometrix R-package software with the web interface app Biblioshiny. We included in the analyses 1,916 papers on EDs and 6491 on schizophrenia.; The ED field published three times less than schizophrenia in top-ranking journals - with letters and notes particularly lacking-notwithstanding a comparable number of papers published per author. Only 50% of top-cited articles focused on EDs and a smaller pool of journals available for ED research (i.e., Zones 1 and 2 according to Bradford's law) emerged; journals publishing on EDs showed an overall lower rank compared to the schizophrenia field. Schizophrenia research was more geographically distributed and more funded; in contrast, a comparable collaboration index was found between the fields.; These data show that research on EDs is currently marginalized and top-rank journals are seldom achievable by researchers in EDs. Such difficulties in research dissemination entail potentially serious repercussions on clinical advancements.; Level V: opinions of respected authorities, based on descriptive studies, narrative reviews, clinical experience, or reports of expert committees.; © 2022. The Author(s).",27,8,3005,3016,Scopus; Publishing; Impact factor; Schizophrenia (object-oriented programming); Schizophrenia research; Web of science; Publication; Specialty; Bibliometrics; Psychology; Vitality; Ranking (information retrieval); Psychiatry; Library science; Medicine; Political science; MEDLINE; Computer science; Law; Philosophy; Theology; Machine learning,Anorexia nervosa; Bibliometry; Binge eating disorder; Bradford’s law; Bulimia nervosa; Schizophrenia,Humans; Journal Impact Factor; Bibliometrics; Feeding and Eating Disorders,,Università degli Studi di Torino,https://link.springer.com/content/pdf/10.1007/s40519-022-01473-9.pdf https://doi.org/10.1007/s40519-022-01473-9,http://dx.doi.org/10.1007/s40519-022-01473-9,36085407,10.1007/s40519-022-01473-9,,PMC9462607,0,001-750-211-629-634; 002-613-958-868-962; 002-839-155-320-807; 003-090-186-926-128; 003-511-074-239-916; 007-515-825-910-656; 010-072-058-987-422; 010-121-905-793-943; 010-129-643-783-396; 011-663-016-379-833; 013-485-101-237-497; 013-507-404-965-47X; 017-170-517-547-578; 020-633-915-817-269; 023-989-205-865-406; 024-204-475-009-910; 028-596-802-787-850; 032-687-387-882-540; 034-859-829-686-290; 035-693-986-011-560; 036-750-240-542-87X; 038-378-668-337-433; 039-671-325-847-916; 041-377-546-080-290; 047-471-579-498-713; 050-545-179-392-458; 058-724-411-250-61X; 064-950-968-199-762; 066-427-764-952-501; 071-903-355-299-99X; 075-644-746-186-898; 077-608-362-187-386; 077-894-367-296-696; 084-483-083-028-179; 084-980-625-686-633; 086-405-198-007-115; 086-453-446-941-780; 086-825-055-778-415; 092-172-209-069-817; 094-207-374-504-472; 094-912-468-525-008; 104-086-257-344-783; 131-983-239-925-735,18,true,cc-by,gold -182-204-216-190-646,Trends in carbon capture technologies: a bibliometric analysis,2022-12-05,2022,journal article,Carbon Neutrality,27313948; 27888614,Springer Science and Business Media LLC,,Sean Ritchie; Elena Tsalaporta,"AbstractClimate change is an ever-present issue, which has a vast variety of potential solutions, one of which being carbon capture. This paper aims to use bibliometric analysis techniques to find trends in carbon capture within the technologies of adsorption, absorption, membranes, and hybrid technologies. The Web of Science core collection database performed bibliometric searches, with the ‘Bibliometrix’ plug-in for R software, performing the bibliometric analysis. Bibliometric data spanned across 1997–2020 and the investigation found that adsorption technologies dominated this period in terms of citations and articles, with hybrid technologies being the least produced but rising in scientific productivity and citations. The Analysis found China and the United States of America to be the dominant producers of articles, with global collaboration being central to carbon capture. The ‘International Journal of Greenhouse Gas Control’ ranked as the top producer of articles however, the ‘ACS Applied Materials & Interfaces’ was the leading journal in terms of H-index.",1,1,,,Greenhouse gas; Bibliometrics; Productivity; Carbon capture and storage (timeline); Data science; Computer science; Environmental science; Climate change; Library science; Economics; Ecology; Biology; Macroeconomics,,,,"Irish Research Council for Science, Engineering and Technology; Shanghai Jiao Tong University",https://link.springer.com/content/pdf/10.1007/s43979-022-00040-6.pdf https://doi.org/10.1007/s43979-022-00040-6,http://dx.doi.org/10.1007/s43979-022-00040-6,,10.1007/s43979-022-00040-6,,,0,002-603-754-333-131; 013-507-404-965-47X; 017-052-410-925-885; 019-313-233-751-727; 021-967-004-917-847; 022-253-558-392-028; 023-238-659-030-756; 027-038-033-293-035; 029-420-167-353-195; 036-082-035-357-965; 038-642-065-512-378; 039-666-576-857-856; 040-167-384-539-932; 040-292-035-608-074; 042-199-465-750-114; 043-012-854-136-760; 049-705-442-283-086; 055-378-680-800-984; 055-458-328-366-429; 057-319-310-846-54X; 059-252-098-641-238; 062-021-479-549-224; 063-573-118-977-209; 063-913-003-220-220; 082-335-863-661-621; 084-620-594-717-935; 086-692-818-048-386; 087-471-099-839-145; 087-838-358-184-39X; 091-408-478-468-084; 101-752-490-869-458; 105-915-861-673-075; 119-970-363-874-210; 143-504-632-283-366; 148-397-721-704-290; 163-011-832-110-160; 186-148-626-913-52X; 186-820-010-429-927,6,true,cc-by,gold -183-007-138-224-890,Review of the literature on the food system and biodiversity loss: a hybrid approach for the identification of research streams and research gaps,2025-03-05,2025,journal article,Euro-Mediterranean Journal for Environmental Integration,23656433; 23657448,Springer Science and Business Media LLC,,Francesca Frieri; Piergiuseppe Morone,,,,,,Identification (biology); STREAMS; Biodiversity; Environmental resource management; Computer science; Environmental science; Ecology; Biology; Computer network,,,,,,http://dx.doi.org/10.1007/s41207-025-00764-8,,10.1007/s41207-025-00764-8,,,0,000-187-310-459-654; 005-357-939-849-239; 005-518-318-514-342; 007-003-559-357-915; 008-789-784-427-936; 010-318-831-989-909; 010-548-604-958-575; 013-507-404-965-47X; 013-541-969-076-695; 014-008-388-232-590; 014-357-010-005-383; 015-587-787-570-47X; 015-732-382-240-470; 016-174-001-292-203; 017-909-560-636-325; 020-312-757-352-701; 022-765-186-427-232; 023-055-841-878-508; 023-927-221-065-800; 025-287-523-014-857; 025-617-188-953-062; 026-238-970-783-151; 026-459-668-136-913; 027-749-394-465-892; 030-008-901-177-984; 032-513-468-017-882; 032-519-936-403-563; 032-599-064-800-133; 034-600-684-728-898; 037-331-683-577-73X; 037-925-123-719-080; 038-853-501-247-049; 040-466-288-442-671; 040-670-927-842-814; 041-440-584-619-09X; 042-649-314-107-311; 043-618-943-962-438; 044-077-330-349-005; 044-173-474-981-00X; 045-422-273-148-899; 046-992-864-415-70X; 046-996-493-943-025; 048-138-367-803-189; 052-957-677-166-510; 054-722-144-244-877; 055-371-263-675-228; 058-634-622-743-263; 059-189-140-108-092; 059-974-139-435-022; 060-759-933-521-220; 063-264-822-040-939; 064-641-641-585-371; 064-644-742-911-82X; 064-962-061-702-25X; 069-382-684-859-211; 074-185-486-226-913; 074-724-471-958-978; 075-019-603-102-008; 075-227-805-962-707; 075-251-604-114-437; 075-350-090-495-191; 076-354-784-808-310; 081-523-568-781-26X; 082-226-762-850-949; 082-228-143-877-463; 083-441-088-361-921; 084-117-281-728-264; 085-970-830-481-36X; 088-050-552-340-811; 093-313-637-965-944; 096-772-468-242-21X; 098-207-621-449-446; 099-941-498-988-796; 100-250-145-829-504; 103-603-990-690-781; 104-151-927-001-666; 109-338-396-612-75X; 110-897-148-335-905; 127-352-832-214-285; 128-745-796-051-522; 129-847-196-563-261; 133-525-040-002-508; 139-941-357-804-825; 146-936-397-464-05X; 148-467-546-678-232; 160-445-359-176-808; 168-868-292-390-628; 171-527-796-090-517; 177-224-358-882-178; 196-716-377-217-747,0,false,, -183-551-633-446-764,"Bibliometric Analysis of Non-coding RNAs and Ischemic Stroke: Trends, Frontiers, and Challenges.",2023-12-08,2023,journal article,Molecular biotechnology,15590305; 10736085,Springer Science and Business Media LLC,United States,Hanrui Zhang; Guquan Ma; Hequn Lv; Yongjun Peng,,67,1,1,15,microRNA; Non-coding RNA; Exosome; Bioinformatics; Ischemic stroke; Microvesicles; Angiogenesis; Long non-coding RNA; Stroke (engine); Medicine; Biology; Computational biology; Gene; RNA; Internal medicine; Ischemia; Genetics; Mechanical engineering; Engineering,Bibliometric; CiteSpace; Ischemic stroke; Non-coding RNAs; VOSviewer,"Humans; Bibliometrics; Ischemic Stroke/genetics; RNA, Untranslated/genetics; MicroRNAs/genetics; RNA, Circular/genetics; RNA, Long Noncoding/genetics; Animals; Biomarkers/metabolism","RNA, Untranslated; MicroRNAs; RNA, Circular; RNA, Long Noncoding; Biomarkers",National Natural Science Foundation of China (82174484); National Natural Science Foundation of China (81973932); The Peak Academic Talents of Jiangsu Hospital of Traditional Chinese Medicine (K2021RC24); The project of Jiangsu Provincial Hospital of Traditional Chinese Medicine (Y2022ZR20),,http://dx.doi.org/10.1007/s12033-023-00981-y,38064146,10.1007/s12033-023-00981-y,,,0,002-052-422-936-00X; 002-514-137-532-528; 004-966-792-683-103; 006-132-848-831-235; 007-015-345-285-571; 007-265-133-032-136; 007-464-857-527-961; 009-643-574-490-384; 013-906-412-862-276; 014-134-909-093-926; 015-007-414-337-866; 017-619-861-837-854; 017-909-156-553-878; 020-104-166-813-098; 021-639-872-859-541; 021-686-228-001-597; 022-896-801-433-504; 022-909-024-465-631; 027-771-625-571-352; 028-146-775-222-214; 028-168-844-675-776; 031-294-193-345-006; 031-558-270-110-582; 033-145-741-247-161; 035-166-216-484-121; 040-903-983-379-152; 041-275-672-518-452; 042-369-898-143-917; 042-728-496-356-516; 048-636-429-904-48X; 051-781-941-305-709; 064-400-499-357-900; 068-132-712-972-951; 069-254-203-682-683; 070-784-322-739-551; 074-982-556-173-776; 093-408-234-343-704; 094-833-563-114-631; 096-113-225-561-807; 096-819-570-165-463; 098-495-797-318-764; 099-044-389-593-904; 106-409-971-010-285; 115-881-650-278-809; 116-390-068-362-861; 119-273-409-860-081; 120-652-974-962-617; 122-833-303-937-547; 123-000-423-671-210; 133-003-537-909-326; 150-897-138-169-57X; 154-799-273-252-276; 155-939-546-482-068; 159-187-294-031-709; 159-256-519-582-20X; 159-966-716-387-856; 195-907-826-133-131; 199-719-093-249-66X,2,false,, -183-621-871-088-318,Examining the developments in scheduling algorithms research: A bibliometric approach.,2022-05-21,2022,journal article,Heliyon,24058440,Elsevier BV,Netherlands,Temidayo Oluwatosin Omotehinwa,"This study examined the developments in the field of Scheduling algorithms in the last 30 years (1992-2021) to help researchers gain new insight and uncover the emerging areas of growth for further research in this field. This study, therefore, carried out a bibliometric analysis of 12,644 peer-reviewed documents extracted from the Scopus database using the Bibliometrix R package for bibliometric analysis via the Biblioshiny web interface. The results of this study established the development status of the field of Scheduling Algorithms, the growth rate, and emerging thematic areas for further research, institutions, and country collaborations. It also identified the most impactful and leading authors, keywords, sources, and publications in this field. These findings can help both budding and established researchers to find new research focus and collaboration opportunities and make informed decisions as they research the field of scheduling algorithms and their applications.",8,5,e09510,e09510,Scopus; Bibliometrics; Computer science; Scheduling (production processes); Data science; Web of science; Field (mathematics); Algorithm; Data mining; Political science; MEDLINE; Mathematics; Pure mathematics; Law; Mathematical optimization,Bibliometric analysis; Bibliometrix; Biblioshiny; Scheduling algorithms; Science mapping,,,,https://www.cell.com/article/S2405844022007988/pdf https://doi.org/10.1016/j.heliyon.2022.e09510,http://dx.doi.org/10.1016/j.heliyon.2022.e09510,35663729,10.1016/j.heliyon.2022.e09510,,PMC9157010,0,001-361-555-872-25X; 007-950-280-143-798; 013-507-404-965-47X; 013-524-854-219-241; 015-692-170-714-052; 016-323-194-812-696; 017-294-791-576-077; 017-750-600-412-958; 018-893-501-990-992; 018-920-312-583-045; 025-248-588-531-626; 025-302-119-966-613; 028-728-563-956-910; 029-016-107-372-314; 031-595-768-347-950; 032-207-813-013-335; 033-148-820-371-578; 034-732-911-805-318; 034-768-039-318-254; 034-999-298-932-628; 040-897-373-580-950; 042-132-862-292-819; 042-166-591-900-071; 045-771-616-576-162; 045-961-475-607-195; 046-992-864-415-70X; 051-126-343-219-957; 051-718-242-940-226; 052-522-335-651-759; 053-828-452-185-660; 054-067-954-199-547; 054-545-845-536-800; 063-063-429-442-543; 063-201-325-167-818; 068-972-920-686-556; 081-103-340-058-998; 084-047-234-957-901; 087-075-424-743-514; 091-186-450-631-758; 098-009-689-044-333; 099-408-876-733-534; 103-295-945-340-625; 103-670-935-448-482; 103-863-894-966-363; 103-943-665-858-641; 106-321-863-451-52X; 107-276-900-991-821; 151-638-417-005-930; 168-851-487-019-051; 170-715-840-217-039,36,true,"CC BY, CC BY-NC-ND",gold -183-765-306-152-412,A bibliometric analysis on the evolution of research in financial accounting,,2024,conference proceedings article,"Challenges of accounting for young researchers, 8th edition",,Academy of Economic Studies of Moldova,,Petronela-Teodora Sîrb (Dulău),"Bibliometrics has become, in the last decades, an essential tool for evaluating and analyzing the results of scientists and of the collaboration between research centers, with bibliometric analysis becoming increasingly popular in recent decades due to the advancement, availability, and accessibility of bibliometric software and scientific databases. The purpose of this study was to examine the number of bibliometric works published over time in the Web of Science database, the fields in which these analyses are most commonly used, how many bibliometric works on financial accounting have been published to date, and the most commonly used keywords in the publication of these works. The use of one of the most popular bibliometric software, Bibliometrix, was intended to provide an analytical model of published works in the field of financial accounting.",,,127,132,Accounting; Computer science; Business,,,,,,http://dx.doi.org/10.53486/issc2024.24,,10.53486/issc2024.24,,,0,,0,false,, -184-121-384-377-230,The GIST of it all: management of gastrointestinal stromal tumors (GIST) from the first steps to tailored therapy. A bibliometric analysis.,2024-03-14,2024,journal article,Langenbeck's archives of surgery,14352451; 14352443,Springer Science and Business Media LLC,Germany,Julian Musa; Sarah M Kochendoerfer; Franziska Willis; Christine Sauerteig; Jonathan M Harnoss; Ingmar F Rompen; Thomas G P Grünewald; Mohammed Al-Saeedi; Martin Schneider; Julian-C Harnoss,"Improvement of patient care is associated with increasing publication numbers in biomedical research. However, such increasing numbers of publications make it challenging for physicians and scientists to screen and process the literature of their respective fields. In this study, we present a comprehensive bibliometric analysis of the evolution of gastrointestinal stromal tumor (GIST) research, analyzing the current state of the field and identifying key open questions going beyond the recent advantages for future studies to assess.; Using the Web of Science Core Collection, 5040 GIST-associated publications in the years 1984-2022 were identified and analyzed regarding key bibliometric variables using the Bibliometrix R package and VOSviewer software.; GIST-associated publication numbers substantially increased over time, accentuated from year 2000 onwards, and being characterized by multinational collaborations. The main topic clusters comprise surgical management, tyrosine kinase inhibitor (TKI) development/treatment, diagnostic workup, and molecular pathophysiology. Within all main topic clusters, a significant progress is reflected by the literature over the years. This progress ranges from conventional open surgical techniques over minimally invasive, including robotic and endoscopic, resection techniques to increasing identification of specific functional genetic aberrations sensitizing for newly developed TKIs being extensively investigated in clinical studies and implemented in GIST treatment guidelines. However, especially in locally advanced, recurrent, and metastatic disease stages, surgery-related questions and certain specific questions concerning (further-line) TKI treatment resistance were infrequently addressed.; Increasing GIST-related publication numbers reflect a continuous progress in the major topic clusters of the GIST research field. Especially in advanced disease stages, questions related to the interplay between surgical approaches and TKI treatment sensitivity should be addressed in future studies.; © 2024. The Author(s).",409,1,95,,GiST; Medicine; Multinational corporation; Translational research; Imatinib mesylate; Imatinib; Stromal cell; Internal medicine; Pathology; Business; Myeloid leukemia; Finance,Bibliometry; GIST; Gastrointestinal stromal tumor; Imatinib; TKI; Tyrosine kinase inhibitor,Humans; Gastrointestinal Stromal Tumors/surgery; Protein Kinase Inhibitors/therapeutic use; Gastrointestinal Neoplasms/surgery; Antineoplastic Agents/therapeutic use,Protein Kinase Inhibitors; Antineoplastic Agents,Bundesministerium für Bildung und Forschung (HEROES-AYA); Bundesministerium für Bildung und Forschung (HEROES-AYA),https://link.springer.com/content/pdf/10.1007/s00423-024-03271-6.pdf https://doi.org/10.1007/s00423-024-03271-6,http://dx.doi.org/10.1007/s00423-024-03271-6,38480587,10.1007/s00423-024-03271-6,,PMC10937785,0,000-919-181-069-131; 001-880-619-468-622; 002-052-422-936-00X; 005-480-749-471-072; 005-621-348-559-328; 005-645-340-430-032; 006-902-349-113-157; 009-443-328-306-813; 013-507-404-965-47X; 015-601-974-132-959; 018-334-832-160-175; 019-823-801-482-765; 021-375-481-018-183; 021-777-567-167-309; 022-134-851-301-883; 025-585-530-763-413; 029-632-283-408-135; 035-425-555-862-290; 035-622-096-375-276; 043-282-577-525-759; 044-971-180-072-43X; 052-679-504-741-92X; 055-671-201-453-114; 056-043-009-177-833; 057-140-001-012-517; 062-045-589-021-806; 062-235-081-204-158; 063-211-974-996-738; 064-264-695-662-36X; 072-763-961-729-261; 077-126-527-812-329; 086-139-481-946-16X; 086-358-658-188-983; 091-785-902-746-80X; 102-112-592-068-839; 103-147-946-767-132; 110-593-746-101-225; 110-809-941-263-238; 111-660-344-275-787; 112-533-001-418-656; 123-245-955-950-291; 125-494-453-043-659; 131-258-284-380-648; 133-604-311-767-509; 139-753-140-102-058; 159-306-125-917-84X,2,true,cc-by,hybrid -184-170-510-093-636,A DECADE OF SCIENTIFIC PRODUCTION ON WATER QUALITY: A BIBLIOMETRIC ANALYSIS OF REGIONAL PERSPECTIVES IN BRAZIL AND HUNGARY (2015-2024),2025-05-23,2025,journal article,Nativa,23187670,Nativa,,Camila Evelyn Rodrigues Pimenta; Gábor Várbiro,"This paper performs a bibliometric analysis on water quality scientific production in Brazil and Hungary based on the Scopus and Web of Science databases for 2015 - 2024. This study aims to exhibit trends, gaps, and patterns in the water quality topic, illustrating the importance of socio-economic development and environmental sustainability. The results show that in Brazil, environmental monitoring, toxicity and phosphorus analysis are the majority focus on scientific research, and in Hungary, similar to Brazil, is also concerned with environmental monitoring mainly based on local ecosystems (e. g. Lake Balaton and the Danube River) as well as subjects such as risk assessment and nutrients analysis. The highlight in both countries is the necessity of commitment to international cooperation, which is necessary to develop innovative and sustainable approaches to water management.; Keywords: Bibliometrix; environmental assessment; scientific cooperation.;  ; Uma década de produção científica sobre qualidade da água: uma análise bibliométrica das perspectivas regionais no Brasil e na Hungria (2015-2024) ;  ; ABSTRACT: Este artigo realiza uma análise bibliométrica da produção científica sobre qualidade da água no Brasil e na Hungria com base nos bancos de dados Scopus e Web of Science do período de 2015 a 2024. O objetivo desse estudo é exibir tendências, lacunas e padrões no tópico de qualidade da água, ilustrando a importância para o desenvolvimento socioeconômico e a sustentabilidade ambiental. Os resultados mostram que, no Brasil, o monitoramento ambiental, análises de toxicidade e de fósforo são o foco principal da pesquisa científica e, na Hungria, similar ao Brasil também se preocupa com a Avaliação ambiental baseando principalmente em ecossistemas locais (por exemplo, o Lago Balaton e o Rio Danúbio), além de temas como avaliação de riscos e análises de nutrientes. O destaque em ambos os países é a necessidade de compromisso com a cooperação internacional necessária para desenvolver abordagens inovadoras e sustentáveis de gerenciamento de água.; Palavras-chave: Bibliometrix; avaliação ambiental; cooperação científica.",13,2,266,276,Production (economics); Quality (philosophy); Geography; Regional science; Economics; Philosophy; Epistemology; Macroeconomics,,,,,,http://dx.doi.org/10.31413/nat.v13i2.19292,,10.31413/nat.v13i2.19292,,,0,013-507-404-965-47X; 014-942-379-319-793; 021-759-238-793-895; 027-637-565-394-050; 030-922-924-199-929; 034-152-325-800-695; 038-690-996-762-646; 044-808-566-509-681; 045-422-273-148-899; 047-502-645-481-506; 049-934-049-957-16X; 052-051-531-740-777; 054-670-081-672-302; 065-060-510-337-74X; 077-147-995-246-420; 091-429-433-584-56X; 093-022-391-419-926; 093-028-437-049-017; 098-377-939-800-955; 101-052-658-737-057; 125-973-473-008-402; 141-562-401-028-854; 145-509-089-227-949; 151-066-640-236-837,0,true,,bronze -184-227-506-894-611,A Bibliometrix Review Based on Secure Cyber-Physical System: Attacks in Industry IoT 4.0,2021-01-01,2021,journal article,SSRN Electronic Journal,15565068,Elsevier BV,,Ankita Sharma,,,,,,Internet of Things; Cyber-physical system; Computer security; Industry 4.0; Business; Computer science; Internet privacy; Embedded system; Operating system,,,,,,http://dx.doi.org/10.2139/ssrn.3883495,,10.2139/ssrn.3883495,,,0,,0,false,, -184-336-700-389-267,Gut microbiota in insulin resistance: a bibliometric analysis.,2024-02-14,2024,journal article,Journal of diabetes and metabolic disorders,22516581,Springer Science and Business Media LLC,United Kingdom,Weiwei Tian; Li Liu; Ruirui Wang; Yunyun Quan; Bihua Tang; Dongmei Yu; Lei Zhang; Hua Hua; Junning Zhao,"Insulin resistance (IR) is considered the pathogenic driver of diabetes, and can lead to obesity, hypertension, coronary artery disease, metabolic syndrome, and other metabolic disorders. Accumulating evidence indicates that the connection between gut microbiota and IR. This bibliometric analysis aimed to summarize the knowledge structure of gut microbiota in IR.; Articles and reviews related to gut microbiota in IR from 2013 to 2022 were retrieved from the Web of Science Core Collection (WoSCC), and the bibliometric analysis and visualization were performed by Microsoft Excel, Origin, R package (bibliometrix), Citespace, and VOSviewer.; A total of 4 749 publications from WoSCC were retrieved, including 3 050 articles and 1 699 reviews. The majority of publications were from China and USA. The University Copenhagen and Shanghai Jiao Tong University were the most active institutions. The journal of Nutrients published the most papers, while Nature was the top 1 co-cited journal, and the major area of these publications was molecular, biology, and immunology. Nieuwdorp M published the highest number of papers, and Cani PD had the highest co-citations. Keyword analysis showed that the most frequently occurring keywords were ""gut microbiota"", ""insulin-resistance"", ""obesity"", and ""inflammation"". Trend topics and thematic maps showed that serum metabolome and natural products, such as resveratrol, flavonoids were the research hotspots in this field.; This bibliometric analysis summarised the hotspots, frontiers, pathogenesis, and treatment strategies, providing a clear and comprehensive profile of gut microbiota in IR.; The online version contains supplementary material available at 10.1007/s40200-023-01342-x.; © The Author(s), under exclusive licence to Tehran University of Medical Sciences 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.",23,1,173,188,Insulin resistance; Resistance (ecology); Computational biology; Biology; Data science; Microbiology; Insulin; Computer science; Biotechnology; Ecology,Bibliometric; Gut microbiota; Insulin resistance; Pathogenesis; Systematic review; Treatment strategies,,,National Natural Science Foundation of China; Sichuan Provincial Administration of Traditional Chinese Medicine; Major Scientific and Technological Special Project of Guizhou Province; Fundamental Research Funds for Sichuan Provincial Scientific Research Institutes,,http://dx.doi.org/10.1007/s40200-023-01342-x,38932838,10.1007/s40200-023-01342-x,,PMC11196565,0,000-113-446-412-116; 000-588-153-087-013; 000-750-491-384-064; 000-811-948-275-375; 001-218-843-989-338; 001-995-273-931-359; 003-211-467-332-623; 003-498-899-844-009; 004-757-282-213-143; 005-103-501-796-726; 006-859-866-120-75X; 008-540-585-304-454; 008-575-571-742-074; 009-369-802-373-018; 009-712-809-123-201; 010-035-153-447-245; 011-215-003-637-478; 011-712-737-053-313; 013-510-035-650-700; 014-487-546-379-151; 015-023-674-242-361; 015-717-827-793-057; 016-180-995-912-026; 016-713-134-019-438; 018-904-405-158-857; 021-580-601-855-035; 022-172-474-723-489; 022-609-190-128-740; 022-691-588-999-808; 022-981-362-544-101; 023-437-848-626-198; 024-112-009-268-204; 024-188-930-822-480; 024-405-499-027-524; 024-517-068-529-334; 024-574-110-887-305; 025-292-032-784-693; 028-098-639-865-852; 028-755-388-328-004; 029-402-569-641-078; 029-966-303-198-869; 030-549-254-217-602; 030-583-762-495-712; 032-524-675-058-47X; 035-882-816-713-423; 037-605-740-086-730; 038-173-984-849-888; 039-043-138-013-759; 040-984-859-102-700; 041-430-523-018-339; 043-854-098-927-962; 047-773-466-623-390; 051-099-847-612-743; 053-843-173-741-543; 055-241-026-306-482; 056-042-855-808-310; 056-726-896-174-403; 057-286-721-499-310; 059-765-695-351-232; 060-112-467-720-945; 060-751-767-650-29X; 061-867-905-160-186; 061-877-295-914-153; 063-833-564-738-433; 064-156-022-623-122; 064-499-898-969-261; 064-619-457-510-133; 064-775-345-825-215; 066-610-996-928-83X; 068-586-696-530-550; 068-646-991-287-372; 068-673-020-948-952; 069-400-594-208-235; 070-164-307-382-593; 071-070-387-594-893; 071-758-653-485-901; 071-773-775-245-469; 072-579-232-607-221; 073-021-386-694-958; 074-637-512-681-130; 075-402-233-960-938; 075-512-728-239-517; 077-386-153-549-685; 077-537-032-303-510; 086-003-100-307-08X; 086-222-483-586-302; 086-449-262-667-017; 088-319-728-263-012; 089-983-162-801-257; 094-085-190-701-014; 095-521-550-808-427; 099-176-212-181-976; 108-673-460-750-260; 108-737-687-551-100; 110-038-690-805-81X; 112-688-263-368-579; 112-956-400-368-718; 113-007-736-346-071; 115-327-014-202-696; 116-210-694-179-609; 116-507-384-909-220; 118-970-953-065-994; 121-180-255-773-928; 124-045-334-761-455; 126-072-955-446-040; 128-024-636-513-601; 131-774-932-613-691; 144-751-509-908-732; 148-070-486-299-701; 151-122-255-226-441; 158-997-087-676-588; 161-401-935-855-57X; 162-813-785-775-802; 171-582-124-568-663; 176-288-052-286-505; 176-393-553-685-71X; 182-894-774-073-947; 186-449-317-800-395,1,true,,unknown -185-085-736-774-936,Mapping the landscape of oral cancer research trends: a systematic scientometric review of global efforts.,2024-04-26,2024,journal article,Oral and maxillofacial surgery,18651569; 18651550,Springer Science and Business Media LLC,Germany,Gyanajeet Yumnam; Rajkumari Sofia Devi; Charoibam Ibohal Singh,,28,3,1077,1093,Medicine; Oral and maxillofacial surgery; Bibliometrics; Web of science; Cancer; Dental research; Library science; Meta-analysis; Internal medicine; Dentistry; Computer science,Bibliometric; Mouth cancer; Oncology; Oral cancer; Scientometric; Web of science,Humans; Bibliometrics; Biomedical Research/trends; Global Health; Mouth Neoplasms; Periodicals as Topic/statistics & numerical data; United States,,Indian Council of Social Science Research (RFD/2021-22/GEN/LIB/345),,http://dx.doi.org/10.1007/s10006-024-01253-y,38664290,10.1007/s10006-024-01253-y,,,0,000-450-282-564-160; 001-340-034-119-905; 001-529-234-291-493; 002-052-422-936-00X; 003-362-412-309-918; 004-393-457-737-674; 007-655-432-423-093; 008-066-008-297-543; 012-383-767-656-272; 012-552-699-306-047; 012-870-711-314-765; 013-462-892-202-044; 013-507-404-965-47X; 018-183-072-522-093; 018-247-727-115-086; 018-393-224-068-367; 020-357-930-020-110; 021-484-985-832-819; 022-465-893-315-278; 025-840-414-689-274; 027-184-863-584-152; 027-778-826-544-993; 029-116-246-233-072; 029-141-729-660-348; 030-244-211-421-438; 030-280-797-755-838; 035-384-946-753-982; 036-306-661-443-73X; 036-707-170-597-715; 039-548-143-430-403; 040-439-983-432-017; 042-822-881-795-436; 045-881-693-065-531; 049-318-862-612-683; 051-022-061-010-606; 051-721-270-129-366; 056-078-671-230-846; 057-935-401-222-248; 060-361-613-630-655; 061-090-075-179-987; 062-412-947-378-904; 063-530-254-881-711; 070-101-162-901-525; 073-099-086-378-638; 076-019-776-003-258; 079-744-620-297-916; 080-261-042-387-352; 083-097-591-282-833; 087-409-179-535-291; 092-092-344-156-593; 094-614-358-471-306; 094-656-237-432-015; 095-258-654-450-233; 101-013-612-944-630; 101-062-525-131-034; 105-680-427-503-360; 107-483-302-885-238; 108-443-897-167-031; 109-458-596-991-906; 110-500-003-775-856; 110-893-698-797-348; 115-511-878-277-441; 117-114-921-212-664; 121-554-217-388-408; 124-100-946-123-381; 135-575-462-406-201; 138-082-835-503-332; 140-726-609-741-415; 143-442-249-251-870; 153-146-318-976-493,0,false,, -185-168-084-299-298,BIBLIOMETRIC ANALYSIS OF THE EVOLUTION OF THEMES AND RESEARCH DIRECTIONS IN ECONOMIC SECURITY IN THE CONTEXT OF DIGITALIZATION,2023-11-27,2023,journal article,Цифрова економіка та економічна безпека,2786541x,Publishing House Helvetica (Publications),,Н.С. Іванова,"The aim of this article is to examine the evolution of scholars' understanding of economic security and identify specific aspects of ensuring economic security in the context of digitisation. To achieve this goal, a combination of methods, such as bibliometric analysis, the matrix method, and retrospective analysis, was employed. The primary data source was the Web of Science (WoS) Core Collection database, which was processed using the R software package bibliometrix. Results of the presented research allow us to assert that the study of economic security cannot disregard themes related to the digitisation of economic processes, emphasising the importance of topics such as “blockchain”, “digitalization” and “digital economy” in creating an effective system for ensuring economic security at all levels of management in the conditions of digitisation.",,9 (09),112,118,Context (archaeology); Economic security; Data science; Web of science; Computer science; Political science; Geography; Archaeology; MEDLINE; Law,,,,,http://dees.iei.od.ua/index.php/journal/article/download/280/267 https://doi.org/10.32782/dees.9-18,http://dx.doi.org/10.32782/dees.9-18,,10.32782/dees.9-18,,,0,013-507-404-965-47X; 014-374-924-975-356; 025-642-011-490-415; 042-433-480-559-521; 154-118-803-729-937; 194-403-311-412-697; 195-133-129-733-338,0,true,,bronze -185-497-953-945-835,Global trends and characteristics of metal-organic frameworks in cancer research: a machine-learning-based bibliometric analysis.,2025-06-01,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Heyuan Niu; Haipeng Du; Zhe Ji; Xiaoping Li; Wanyi Xiao; Anqi He; Ping Yu; Gang Liu,"Cancer poses a significant health threat, causing millions of deaths annually. Although chemotherapy-based comprehensive therapies are common, their low accuracy and severe side effects limit effectiveness. Metal-organic frameworks (MOFs), with their superior biocompatibility and stability, show great promise for drug delivery and cancer treatment. This study aims to explore the potential and developmental trajectories of MOFs in cancer research through a bibliometric analysis.; The Web of Science Core Collection was searched for documents from its inception in 2009 to December 31, 2023. We analyzed and visualized document types, countries, institutions, authors, journals, references, and keywords using the Bibliometrix package, dplyr, sankeywheel, term extraction, and ggplot2. Additionally, the Latent Dirichlet Allocation (LDA) algorithm was employed for detailed semantic analysis, uncovering latent thematic distributions.; A total of 7106 authors from 1591 institutions across 45 countries contributed 1955 papers on MOFs in cancer research, published in 327 journals. China leads in research output and international collaboration, with the Chinese Academy of Sciences as the top institution. Lin Wenbin from the University of Chicago is the most influential author, and ACS Applied Materials & Interfaces is the most active journal. MOFs are predominantly studied for breast cancer, followed by lung and liver cancers. Drug delivery remains a focal point for future research.; This study provides a comprehensive overview of the research landscape on MOFs in cancer treatment, offering insights into key trends and future directions, particularly in drug delivery and disease-specific applications.; © 2025. The Author(s).",16,1,978,,,Bibliometric analysis; Cancer; Latent Dirichlet Allocation; Metal–organic frameworks,,,Tianjin Key Medical Discipline (Specialty) Construction Project (TJYXZDXK-005A),,http://dx.doi.org/10.1007/s12672-025-02716-8,40450655,10.1007/s12672-025-02716-8,,PMC12127249,0,000-085-518-764-247; 011-759-975-147-217; 011-792-237-325-039; 013-507-404-965-47X; 014-309-831-784-090; 016-636-200-461-691; 024-798-082-115-49X; 026-435-466-313-815; 028-795-653-725-710; 035-896-948-841-416; 042-170-610-095-672; 046-530-878-965-319; 053-554-472-607-984; 055-492-145-257-958; 064-385-822-728-028; 072-576-529-011-222; 082-173-838-814-359; 083-406-917-300-189; 084-540-241-347-334; 093-781-708-899-102; 094-767-313-086-102; 098-725-673-478-054; 100-609-227-350-394; 110-631-597-682-875; 111-267-669-053-209; 112-074-226-760-110; 116-337-260-102-215; 123-720-794-878-03X; 154-502-469-093-799; 157-560-501-513-162; 162-705-901-839-52X; 168-010-136-506-61X; 168-353-389-705-267; 172-515-554-198-275; 173-604-835-639-007; 174-803-558-318-704; 184-589-882-053-777; 189-248-823-334-604; 193-869-495-175-611,0,true,cc-by,gold -185-567-665-080-751,Advances in the innovation of management: a bibliometric review,2023-05-24,2023,journal article,Review of Managerial Science,18636683; 18636691,Springer Science and Business Media LLC,Germany,Xiya Lin; Samuel Ribeiro-Navarrete; Xiaohui Chen; Bing Xu,"As the production model transforms from industrial manufacturing to a knowledge-based economy, management innovation becomes a strong driving force for economic growth and social development. This study examines academic findings on management innovation using the latest bibliometric methods and visualization tools based on papers published in top management journals in the Web of Science database from 2008 to 2022. (1) There are three main research hotspots. Through citation orientation, the research hotspots are business model innovation and environmental innovation; through outcome orientation, the research hotspot is knowledge innovation; and through intermediary orientation, the research hotspot is open innovation. (2) Regarding the distribution of major research institutions, seven institutions in the United States focus on innovation research and have a high impact. Six institutions in the United Kingdom focus on innovation research. Meanwhile, nine and three related institutions in Europe and Asia focus on innovation research, respectively. (3) Distribution of innovation articles in journals, Research Policy , Technovation , Journal of Product Innovation Management , and Industrial Marketing Management , contains the largest number of innovation research articles. Furthermore, this study examines new hot topics with time change and digital innovation. This paper provides the latest overview of innovation research in management and discusses the evolution and development of this field.",18,6,1557,1595,Innovation management; Hotspot (geology); Open innovation; Bibliometrics; Business; Knowledge management; Product innovation; Regional science; Marketing; Computer science; Sociology; Library science; Geophysics; Geology,,,,,https://link.springer.com/content/pdf/10.1007/s11846-023-00667-4.pdf https://doi.org/10.1007/s11846-023-00667-4,http://dx.doi.org/10.1007/s11846-023-00667-4,,10.1007/s11846-023-00667-4,,,0,002-052-422-936-00X; 007-026-572-181-928; 007-203-172-710-768; 007-836-400-575-60X; 010-580-438-028-363; 010-639-447-111-568; 011-301-822-302-672; 012-702-349-593-905; 013-507-404-965-47X; 013-596-882-149-255; 014-448-392-124-452; 014-913-830-475-043; 016-757-725-246-194; 017-153-449-730-092; 017-953-591-862-200; 018-345-855-897-35X; 018-460-854-153-475; 019-259-889-795-066; 019-941-656-009-054; 020-067-709-218-691; 022-658-928-602-180; 023-927-221-065-800; 024-701-921-003-429; 024-721-106-603-493; 024-863-314-645-595; 025-402-274-938-418; 025-799-728-682-399; 026-169-050-342-031; 028-010-910-489-622; 030-428-629-091-217; 034-263-152-088-952; 037-018-908-776-748; 037-423-808-976-557; 037-815-640-424-494; 039-802-123-710-062; 040-565-427-054-980; 040-789-926-270-357; 043-048-430-731-341; 043-803-133-035-741; 044-858-555-385-906; 045-993-333-977-461; 046-142-939-540-134; 046-653-356-123-499; 047-545-845-603-280; 047-809-062-688-915; 048-218-940-326-654; 052-760-984-912-342; 053-295-670-541-193; 053-929-922-443-752; 054-046-934-960-770; 054-818-565-070-154; 057-364-803-902-688; 063-757-530-177-971; 065-934-110-209-938; 067-434-230-643-941; 068-259-085-977-283; 074-459-960-544-86X; 075-208-870-396-699; 079-808-846-973-817; 080-977-108-232-315; 082-291-967-083-57X; 085-001-502-383-40X; 086-341-446-522-651; 086-876-206-944-354; 094-177-617-833-47X; 095-258-654-450-233; 098-423-565-141-83X; 100-294-259-882-658; 100-603-573-401-580; 105-402-220-957-576; 107-276-900-991-821; 108-221-825-120-53X; 108-374-777-345-415; 118-912-306-011-898; 123-628-833-025-039; 125-212-750-683-224; 128-671-364-070-384; 132-749-941-950-472; 133-124-119-086-276; 134-214-033-689-653; 147-724-863-924-60X; 158-153-629-834-756; 161-451-416-501-29X; 162-644-879-394-037; 164-225-841-088-815; 167-517-393-664-826; 177-333-702-180-734; 178-050-721-222-705; 183-887-644-618-321,15,true,,bronze -185-609-084-675-100,A study on supply chain 5.0 research: A visual analysis by bibliometrix R-tool,2025-04-30,2025,journal article,Erciyes Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi,13013688; 26306409,Erciyes Universitesi,,Yeşim Deniz Özkan Özen,"Studies on recent industrial developments and their impacts are one of the majorities of the current literature, and it is a rapidly growing area. With this view, this paper presents a comprehensive bibliometric analysis of research on Supply Chain 5.0 (SC 5.0), an emerging paradigm that integrates Industry 5.0 principles with supply chain management to enhance human-machine collaboration, sustainability, and resilience. Utilizing data from prominent academic databases, this study examines the evolution of SC 5.0 research and identifies key themes. Bibliometrix software, which uses R language and is therefore known as R-tool, is utilized for analysis. It employs various bibliometric techniques, including co-occurrence analysis, keyword co-occurrence, and thematic mapping, to uncover the intellectual structure and trends within the field. Findings reveal a rapid publication growth, emphasizing technological advancements, sustainability, and human-centric approaches. At the end of the study, future research ideas are presented under the themes of supply chain resilience and agility, human-centric approaches in supply chains, impacts of SC 5.0 in emerging economies, and sustainable SC 5.0 concepts. This paper contributes to the academic discourse by providing a detailed overview of the current state of SC 5.0 research, highlighting gaps, and suggesting future research directions to advance the field.",,70,177,183,Supply chain; Computer science; Business; Marketing,,,,,,http://dx.doi.org/10.18070/erciyesiibd.1573101,,10.18070/erciyesiibd.1573101,,,0,013-507-404-965-47X; 014-461-422-898-333; 022-943-664-043-241; 025-302-119-966-613; 025-563-348-529-076; 026-554-120-193-424; 035-953-579-141-278; 038-381-069-504-604; 043-306-859-214-901; 049-695-810-690-712; 055-558-955-490-515; 062-467-280-319-815; 064-138-810-036-202; 069-895-471-872-643; 070-609-833-244-587; 073-760-338-998-200; 076-458-739-141-461; 083-320-862-823-849; 083-608-958-244-975; 094-857-445-530-745; 096-960-122-002-399; 111-534-063-351-205; 133-976-408-988-84X; 146-576-589-004-959; 161-320-457-535-461; 167-090-539-907-932; 178-395-393-201-588; 180-095-022-258-312; 199-518-818-774-074,0,true,,gold -185-900-584-924-090,Exploring two decades of research on online reading by using bibliometric analysis,2023-12-08,2023,journal article,Education and Information Technologies,13602357; 15737608,Springer Science and Business Media LLC,United Kingdom,Jie Li; Fei Lin; Tianxi Duan,,29,10,12831,12862,Scopus; Reading (process); Theme (computing); Bibliometrics; Hypertext; Comprehension; The Internet; Reading comprehension; Computer science; Library science; Data science; World Wide Web; Political science; MEDLINE; Law; Programming language,,,,NA,,http://dx.doi.org/10.1007/s10639-023-12306-2,,10.1007/s10639-023-12306-2,,,0,000-726-801-058-601; 000-848-264-004-813; 002-544-146-687-158; 002-774-419-560-624; 002-880-668-566-903; 005-814-386-042-419; 006-351-772-268-027; 006-519-755-738-273; 007-196-303-009-961; 010-194-028-604-828; 013-430-585-787-402; 013-507-404-965-47X; 015-298-603-836-501; 016-089-196-099-991; 019-706-511-878-953; 020-212-524-764-299; 020-325-964-593-789; 020-779-628-203-493; 024-773-653-005-788; 026-395-112-558-483; 027-671-321-246-878; 028-846-935-406-555; 031-607-161-110-717; 035-062-743-363-966; 039-229-652-928-607; 042-614-676-598-365; 044-968-488-355-826; 048-405-788-790-922; 048-840-500-085-391; 049-811-209-642-811; 049-829-064-345-669; 050-283-449-504-337; 053-454-063-805-412; 053-990-076-703-641; 055-232-106-827-937; 055-616-786-130-094; 055-956-013-020-927; 058-018-139-028-076; 062-955-554-667-802; 063-028-953-938-760; 064-400-499-357-900; 066-220-797-289-285; 071-298-669-979-418; 071-479-297-994-010; 071-631-922-255-808; 074-475-509-365-285; 075-506-987-102-661; 076-498-170-063-038; 078-934-786-115-685; 080-264-891-593-912; 083-298-249-575-172; 087-945-329-691-513; 089-396-471-120-168; 093-172-457-662-51X; 096-436-306-380-879; 096-589-224-217-186; 101-752-490-869-458; 107-060-026-229-378; 107-518-655-388-824; 110-353-498-208-759; 110-916-521-494-666; 112-603-944-485-011; 112-708-016-079-492; 114-352-973-897-348; 114-598-817-362-245; 121-909-303-740-72X; 130-077-213-554-584; 132-252-987-300-762; 134-625-190-133-559; 134-700-350-694-767; 136-944-654-710-678; 137-915-834-689-865; 145-356-972-378-186; 170-804-039-919-072; 187-399-935-518-550; 197-606-019-132-507,1,false,, -186-075-945-014-850,Mapping The Web Of Knowledge: A Bibliometric Analysis Of Stock Markets Interlinkage,2025-03-29,2025,journal article,Journal of Information Systems Engineering and Management,24684376,Science Research Society,,null Dr. Ishwar Sharma,"The current study aims to provide an overview of existing research on stock market interlinkage and recommend further research directions. The study performed a bibliometric analysis of 1537 Scopus-indexed papers published since 2000 using biblioshiny under the bibliometrix R package. It describes the status of publications, publication trend, the top productive contributor, the leading influential contributor, the most frequently used keywords, important themes, research collaboration network, co-citation network, and scope of future research. Overall, this analysis contributes to a better understanding of the linkage between stock markets and provides insights for policymakers, managers, analysts, investors, and researchers in this field. More research needs to be conducted to investigate the connections between various financial markets, including the stock, bond, commodity, and currency markets, using statistical models with machine learning algorithms to understand better how financial market interlinkage can affect diversification opportunities and risk management strategies",10,29s,534,558,Stock (firearms); Business; World Wide Web; Computer science; Geography; Archaeology,,,,,,http://dx.doi.org/10.52783/jisem.v10i29s.4503,,10.52783/jisem.v10i29s.4503,,,0,,0,true,,gold -186-136-736-131-635,Sustainability in the arctic: a bibliometric analysis,2024-06-20,2024,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Fatma Ahmed; Oscar Zapata; Greg Poelzer,"AbstractThis paper examines the literature on the Sustainability in the Arctic region, using a bibliometric analysis of 213 English-language articles published between 1980 and 2022 exploiting Bibliometrix, an R package. To find relevant literature using the Web of Science (WOS) database, we searched for documents using mesh terms based on the query of two terms, “Arctic & Sustainability”. We used the Boolean operator “AND” to combine the two terms and the Boolean operator “OR” to include synonyms of the terms. The articles retrieved were authored by 724 researchers, published in 98 journals, representing 132 countries, and growing at 5.08% annually. The findings reveal that a substantial portion of the Arctic sustainability literature placed significant emphasis on the examination of climate change, adaptation, and vulnerabilities affecting local communities. Furthermore, the more recent publications in this field concentrate predominantly on exploring perceptions and governance.",5,1,,,Arctic; Sustainability; The arctic; Geography; Environmental science; Oceanography; Geology; Ecology; Biology,,,,National Science Foundation,https://link.springer.com/content/pdf/10.1007/s43621-024-00312-4.pdf https://doi.org/10.1007/s43621-024-00312-4 https://www.researchsquare.com/article/rs-4125623/latest.pdf https://doi.org/10.21203/rs.3.rs-4125623/v1,http://dx.doi.org/10.1007/s43621-024-00312-4,,10.1007/s43621-024-00312-4,,,0,000-659-274-610-38X; 001-280-575-367-993; 001-915-352-284-492; 002-112-299-610-507; 007-686-932-781-817; 011-586-733-295-652; 013-067-367-029-28X; 013-507-404-965-47X; 014-662-358-404-474; 017-750-600-412-958; 019-350-516-274-409; 024-706-940-128-529; 028-021-611-755-293; 028-292-405-887-994; 028-632-868-365-330; 028-705-313-936-712; 032-999-172-139-947; 033-383-253-891-840; 038-176-242-681-768; 039-176-706-856-738; 042-755-259-129-09X; 047-696-089-455-689; 048-613-260-641-781; 049-568-585-906-596; 054-159-894-171-769; 059-756-553-067-40X; 062-445-809-817-439; 066-339-933-525-835; 068-261-448-233-80X; 068-948-451-621-193; 071-959-920-519-880; 078-273-210-723-922; 080-133-328-475-183; 081-507-744-009-35X; 083-137-544-456-89X; 089-779-267-791-368; 094-294-301-073-390; 096-786-974-963-818; 098-279-162-885-611; 099-468-079-596-586; 099-612-439-451-502; 101-283-143-114-350; 102-152-459-676-567; 115-704-036-075-908; 119-767-093-738-759; 127-958-092-071-907; 131-611-131-716-416; 132-499-382-960-164; 141-770-516-078-794; 143-473-553-783-355; 145-754-191-280-905; 145-873-954-571-324; 149-103-843-800-504; 150-071-180-535-86X; 151-056-508-990-403; 166-877-899-708-163; 171-620-517-093-536; 172-185-739-609-414; 181-843-261-672-147,3,true,cc-by,gold -186-277-866-000-94X,"Supplementary Material - Overview of the global research on dung-inhabiting fungi: trends, gaps, and biases",2023-01-01,2023,dataset,Figshare,,,,Francisco Calaça; Jéssica Conceição Araújo; Carlos de Melo e Silva-Neto; Solange Xavier-Santos,"The file contains the supplementary data to Calaça et al's paper ""Overview of the global research on dung-inhabiting fungi: trends, gaps, and biases"", to the Current Research in Environmental & Applied Mycology (Journal of Fungal Biology). The spreadsheet named 'calaca_dung_fungi' is a database organized from data retrieved from the Web of Science and Scopus databases and merged and cleaned according to the criteria established in the manuscript using the different functions available in the bibliometrix package (Aria & Cuccurullo 2017) for the R environment. In this way, both fonts, style, and formatting of the database in data.dung.fungi, follow the necessary structure for uploading in the R environment using the code: install.packages(""bibliometrix"") + library(bibliometrix) + data <-read.csv(""~/desktop/calaca_database_dungfungi.csv"") + M <- convert2df(data, dbsource = ""wos"", format = ""csv"") + head(M[""TC""])",,,,,Environmental science; Ecology; Geography; Biology,,,,,https://figshare.com/articles/dataset/Supplementary_Material_-_Overview_of_the_global_research_on_dung-inhabiting_fungi_trends_gaps_and_biases/22300636,http://dx.doi.org/10.6084/m9.figshare.22300636,,10.6084/m9.figshare.22300636,,,0,,0,true,cc-by,gold -186-750-802-267-267,Development of online education satisfaction research in 2011–2022: A systemic review based on bibliometric and content analysis,2023-06-22,2023,journal article,Education and Information Technologies,13602357; 15737608,Springer Science and Business Media LLC,United Kingdom,Xingrong Guo; Xiang Li,,29,3,3461,3496,Psychology; Structural equation modeling; Citation; Content analysis; Field (mathematics); Sample (material); Knowledge management; Citation analysis; Educational technology; Medical education; Computer science; Mathematics education; Sociology; Social science; World Wide Web; Medicine; Mathematics; Pure mathematics; Chemistry; Chromatography; Machine learning,,,,,,http://dx.doi.org/10.1007/s10639-023-11894-3,,10.1007/s10639-023-11894-3,,,0,002-052-422-936-00X; 004-504-164-127-468; 004-958-437-193-011; 005-641-047-839-340; 006-610-288-768-330; 007-243-566-125-55X; 009-339-536-254-982; 010-448-128-972-502; 011-057-105-680-492; 011-495-687-670-322; 013-060-275-301-07X; 013-507-404-965-47X; 015-015-282-840-40X; 017-213-174-842-790; 017-797-475-540-237; 018-050-731-275-657; 018-392-325-202-807; 018-536-746-453-84X; 018-564-713-911-021; 019-443-699-376-231; 020-130-447-807-46X; 021-439-220-738-334; 023-333-357-668-653; 024-692-191-294-495; 025-268-078-320-966; 026-959-266-386-881; 029-333-106-032-827; 029-381-988-467-078; 036-126-967-417-405; 037-340-186-273-182; 038-725-017-707-457; 042-130-128-262-966; 042-204-959-947-180; 042-911-354-037-478; 045-993-333-977-461; 046-351-093-542-101; 049-391-379-302-694; 050-999-733-659-946; 051-271-683-284-684; 051-797-397-476-868; 052-870-025-638-314; 052-923-935-274-43X; 053-527-948-927-585; 054-025-920-267-534; 054-818-565-070-154; 055-122-949-542-465; 055-143-658-061-058; 057-545-266-163-64X; 057-632-703-338-475; 058-752-901-180-958; 058-989-762-188-102; 060-017-010-971-60X; 061-691-041-169-135; 064-235-875-047-978; 069-495-841-375-087; 070-300-076-745-513; 071-878-836-294-733; 073-896-640-728-861; 074-324-127-600-19X; 077-196-036-836-995; 079-104-934-656-082; 079-239-786-749-129; 080-998-854-885-900; 081-377-992-364-999; 082-414-097-950-349; 083-458-639-606-712; 084-587-621-565-040; 086-743-981-137-079; 088-319-494-700-450; 091-112-713-025-572; 107-120-679-507-461; 108-555-873-059-550; 110-265-743-090-652; 111-555-387-316-222; 122-415-544-444-960; 123-457-102-588-651; 143-875-130-007-110; 145-684-165-889-660; 146-208-436-691-12X; 151-484-178-281-436; 152-995-257-847-689; 165-861-647-270-529,3,false,, -186-945-698-882-285,Research trends in fracture-related infection: a bibliometric analysis and visualization study from 2017-2025.,2025-06-04,2025,journal article,Archives of orthopaedic and trauma surgery,14343916; 09368051,Springer Science and Business Media LLC,Germany,Oluwasegun Aremu,,145,1,333,,,Bibliometrics; Data visualization; Database management systems; Fracture-related infection,"Bibliometrics; Humans; Fractures, Bone/complications; Biomedical Research/trends; Surgical Wound Infection",,,,http://dx.doi.org/10.1007/s00402-025-05938-1,40465021,10.1007/s00402-025-05938-1,,,0,000-603-903-097-230; 002-052-422-936-00X; 003-868-747-830-164; 011-442-496-588-001; 013-507-404-965-47X; 018-231-132-350-953; 034-616-423-073-594; 047-134-478-431-993; 047-238-560-598-852; 047-563-734-326-38X; 054-086-824-933-161; 060-531-252-973-087; 071-878-836-294-733; 073-367-985-641-83X; 084-906-951-717-102; 088-984-481-455-564; 090-166-913-333-753; 101-752-490-869-458; 111-402-959-532-303; 123-202-581-406-928; 126-897-142-036-534; 130-348-276-035-425; 149-228-754-084-402; 170-888-850-768-809,0,false,, -187-237-444-721-712,"Competencia digital, profesorado y educación superior",2023-02-08,2023,journal article,HUMAN REVIEW. International Humanities Review / Revista Internacional de Humanidades,26959623,Eurasia Academic Publishing Group,,Andrés Cisneros-Barahona; Luis Marqués Molías; Nicolay Samaniego-Erazo; María Isabel Uvidia-Fassler; Wilson Castro-Ortiz; Henry Villa-Yánez,"Haciendo uso de paquete informático Bibliometrix y de la Guía Prisma, se desarrolló un análisis bibliométrico de la literatura proveniente de la Web of Science sobre la competencia digital docente universitaria. Se delimita la investigación a través de tesauros de Eric. Se plantearon preguntas de investigación relacionadas con las fuentes de datos, los autores y las redes de colaboración. La investigación evidencia incrementos en la producción a partir del año 2019, la nacionalidad de los autores y la filiación de instituciones resaltan a través de redes de investigaciones extendidas en Iberoamérica. Es necesario ampliar este estudio a otras bases científicas.",12,Monográfico,1,20,,,,,,,http://dx.doi.org/10.37467/revhuman.v12.4680,,10.37467/revhuman.v12.4680,,,0,001-207-501-099-42X; 001-451-636-355-843; 003-190-802-899-804; 003-722-251-461-869; 003-872-675-322-364; 006-068-362-798-128; 007-322-400-569-332; 007-734-976-791-420; 010-824-958-921-305; 014-939-994-984-923; 015-170-428-339-678; 017-223-012-396-918; 017-394-279-330-244; 019-609-049-036-080; 020-184-794-627-889; 021-792-723-475-967; 023-885-170-368-525; 025-821-538-253-591; 029-510-581-755-316; 042-016-589-369-361; 046-914-262-733-168; 050-516-636-125-468; 052-505-813-320-897; 054-776-041-446-795; 054-902-233-912-433; 056-157-601-516-617; 059-283-456-947-256; 064-988-019-412-326; 065-961-020-425-059; 067-802-630-985-170; 069-906-713-629-998; 079-721-148-600-456; 087-903-294-097-024; 093-904-117-475-655; 104-489-077-105-239; 118-314-694-859-187; 118-805-369-132-781; 123-200-079-644-42X; 125-420-212-519-87X; 128-172-611-288-449; 139-937-031-195-626; 144-747-565-316-983; 145-035-299-045-615; 164-267-516-952-417; 168-546-950-987-37X,9,false,, -187-411-985-682-278,Exploratory review of the scientific production of 5-blind soccer with the Bibliometrix tool,2025-06-07,2025,journal article,Retos,19882041; 15791726,JURUFRA SL,Spain,Boryi Alexander Becerra Patiño; José Pino-Ortega; Jorge Olivares-Arancibia,"Background/Objective. Different studies have investigated blind 5-a-side football through quantitative and qualitative studies, seeking to identify the factors that influence the practice of this sport. However, to date, no exploratory review has been reported that identifies research trends on blind 5-a-side football. The aim was to provide an overview of the research area on blind 5-a-side football to identify trends and research gaps in this topic.; Materials and methods. Research was conducted through the following databases: Scopus, Web of Science, PubMed, ScienceDirect, and Google Scholar. Finally, a total of 85 documents were included. Analyses were performed using the R program Bibliometrix, considering the occurrence of authors, keywords, institutional affiliations, countries and journals.; Results. Quantitative studies are prevalent (84.70%) versus qualitative studies (12.94%) and mixed designs (2.35%). Most studies focus on injury studies, body composition, and to a lesser extent, on the analysis of external load in competition and the study of technical-tactical variables. The most prolific author is Gamonales, J.M., with 10 studies reported in Scopus. Brazil and Spain are the most productive countries, with English being the predominant language. The journal with the largest number of published documents is Retos. the most frequently cited concepts are humans, young adults, and injuries.; Conclusions. The analysis of scientific production on blind 5-a-side football reveals the need for more studies in other areas that have been less explored, including studies on technical, psychological, and psychosocial variables. Ultimately, this could result in a greater impact and reach of blind 5-a-side football in various contexts, allowing for a deeper understanding of the relationship between different performance factors.",68,,1025,1047,,,,,,,http://dx.doi.org/10.47197/retos.v68.115790,,10.47197/retos.v68.115790,,,0,,1,true,cc-by,gold -187-629-834-307-165,Preprocesamiento de publicaciones acerca de indentidad digital descentralizada y autgobernada.,2022-01-01,2022,dataset,Figshare,,,,Roberto Pava,Referencias en formato bibtex obtenidas de las bases de datos Scopus y WoS. Preprocesamiento con el paquete bibliometrix,,,,,Humanities; Computer science; Philosophy,,,,,https://figshare.com/articles/dataset/Referencias_sobre_SSI_obtenidas_en_formato_bibtex/19579492/3,http://dx.doi.org/10.6084/m9.figshare.19579492.v3,,10.6084/m9.figshare.19579492.v3,,,0,,0,true,cc-by,gold -187-980-086-072-476,"Econophysics, State of the Science and Bibliographic Production: a Bibliometric Analysis",2024-11-27,2024,journal article,Revista de Gestão Social e Ambiental,1981982x,RGSA- Revista de Gestao Social e Ambiental,Brazil,Rui Manuel dos Santos Vigário Rodrigues; Thiago Pires Santana; Rui Manuel Teixeira Santos Dias; Aloísio Machado da Silva Filho; Rosa Galvão; Gilney Figueira Zebende; Sidalina Gonçalves,"Objective: This article aims to investigate the state of the art regarding the scientific production of Econophysics as a field of study. The aim is to map the annual production of articles, types of documents, most relevant authors, most productive countries, institutions, journals, scientific collaboration networks, and associated themes and trends.;  ; Theoretical Framework: Econophysics applies physics procedures to analyze financial markets and solve economic problems, using tools such as fractal theory and Brownian motion. The term Econophysics was created by H. Eugene Stanley in 1995. Bibliometric mapping, conducted with software such as Bibliometrix and R-Project, is essential for understanding trends in the academic literature on Econophysics.;  ; Method: Bibliometric analysis was used to map the existing scientific literature on the field of Econophysics. This science is described as a method that employs the resources of mathematics, statistics, and computing to bring the scientific memory of a specific area of knowledge. The Scopus database was used to collect data on the main publications during the period from 1996 to 2024. The Bibliometrix and R-Project software produced keyword co-occurrence maps, citation analysis, and collaboration networks between authors and institutions. The main metrics analyzed include the number of publications per year, the main thematic areas, the sources of publications, the most cited authors, and the geographical distribution of scientific contributions.;  ; Results and Discussion: A total of 1,805 publications between 1996 and 2024 (June), of which 1,450 are scientific articles related to Econophysics. The data suggest a consistent increase in article publications until 2006, after which there was stability between 80 to 100 articles published annually. The percentage of international collaboration is 20.83%, highlighting the collaborative aspect among various countries. The average number of citations of the articles is 22.41%. When analyzing the co-occurrence of keywords, the three main thematic groups were identified—finance, physics, and economics—and the most frequently used terms were trade and financial markets. 793 articles were published by the journal Physica A, which leads the publication ranking. Zhou, Stanley, and Mantegna are the most productive and highly referenced writers. And the nations that contribute the most to the development of Econophysics are China, the United States of America, and Japan.;  ; Research Implications: It is a broader view of the evolution of Econophysics, the main trends, and the areas of research that have emerged in recent decades. It helps understand how physics algorithms can be used to solve economic problems, promoting a more equitable economy.;  ; Originality/Value: This study pioneers the conducting of a comprehensive bibliometric analysis of the literature on econophysics, a relatively new field that combines physical science and economics. The originality lies in the application of various analysis methods through the Bibliometrix and R-Project software to map and analyze the scientific production in this area, providing a better understanding of the evolution and current state of the research. This work contributes to the literature by providing a detailed overview of research trends, main contributions, and gaps in knowledge.;  ",18,11,e010035,e010035,Econophysics; Production (economics); State (computer science); Bibliometrics; Regional science; Data science; Sociology; Computer science; Library science; Economics; Neoclassical economics; Macroeconomics; Algorithm,,,,,,http://dx.doi.org/10.24857/rgsa.v18n11-234,,10.24857/rgsa.v18n11-234,,,0,001-054-371-839-13X; 001-356-642-142-611; 002-052-422-936-00X; 004-265-736-387-287; 009-613-361-959-276; 012-368-749-546-98X; 013-507-404-965-47X; 016-889-902-825-90X; 026-642-812-740-652; 030-216-666-110-152; 031-198-894-494-661; 031-233-450-414-481; 035-550-586-180-48X; 041-140-515-388-932; 042-884-374-208-122; 046-992-864-415-70X; 049-391-379-302-694; 053-874-717-947-833; 054-799-907-427-870; 057-366-599-376-500; 057-811-761-111-336; 063-942-872-281-052; 069-511-868-544-95X; 079-388-097-137-118; 091-816-256-120-499; 097-711-465-809-660; 109-726-720-389-508; 113-021-432-430-523; 118-419-501-591-315; 118-742-703-613-842; 120-885-678-404-810; 130-396-474-013-311; 152-824-713-619-051; 154-535-414-802-675; 166-143-440-676-222; 179-514-382-194-189; 195-416-431-287-471,0,false,, -188-261-564-975-81X,USO DA ANÁLISE BIBLIOMÉTRICA COMO FERRAMENTA PARA O LEVANTAMENTO DE ESTUDOS SOBRE A METABOLÔMICA APLICADA NA BIORREMEDIAÇÃO DE ÁREAS IMPACTADAS POR HIDROCARBONETOS,,2022,journal article,Química Nova,01004042; 16787064,Sociedade Brasileira de Quimica (SBQ),Brazil,Bruna da Costa; Camila Dantas; Beatriz Miranda; Danusia Lima; Olívia Maria de Oliveira; Karina Garcia; Gisele Canuto; Leonardo Teixeira,"USE OF BIBLIOMETRIC ANALYSIS AS A TOOL FOR SURVEYING STUDIES ON METABOLOMICS APPLIED TO THE BIOREMEDIATION OF AREAS IMPACTED BY HYDROCARBONS. Bibliometric reviews, carried out from access to databases of scientific articles associated with software for data processing, can be helpful for qualitative and quantitative assessments of existing publications on a given topic. Several petroleum hydrocarbons are carcinogenic and immunotoxic agents, causing adverse effects on the biota, and the study of metabolites generated in bioremediation processes has been the object of current research. Therefore, in this work, the use of bibliometric analysis as a tool for surveying studies on the applied metabolomics bioremediation of areas impacted by hydrocarbons is presented. A bibliometric review was carried out in the Scopus Preview and Web of Science databases with data analysis using RStudio software with the bibliometrix package. The survey gathered the studies and prominent publications of the last seven years, making it possible to present gaps and opportunities in the area.",,,,,Bioremediation; Web of science; Computer science; Environmental science; Chemistry; Biology; MEDLINE; Contamination; Ecology; Biochemistry,,,,,,http://dx.doi.org/10.21577/0100-4042.20170960,,10.21577/0100-4042.20170960,,,0,,0,true,cc-by-nc,gold -188-546-849-520-471,Aprendizado de máquina aplicado a investigação de perda de água: análise bibliométrica e exploratória do pacote bibliometrix,2024-11-07,2024,conference proceedings article,Anais do Encontro Nacional de Engenharia de Produção,23183349,ENEGEP 2024 - Encontro Nacional de Engenharia de Produção,,OLGA MARIA FORMIGONI CARVALHO WALTER; ELISA HENNING; ANDRÉA CRISTINA KONRATH,,,,,,Computer science,,,,,http://www.abepro.org.br/biblioteca/TN_ST_419_2066_47918.pdf https://doi.org/10.14488/enegep2024_tn_st_419_2066_47918,http://dx.doi.org/10.14488/enegep2024_tn_st_419_2066_47918,,10.14488/enegep2024_tn_st_419_2066_47918,,,0,,0,true,,bronze -188-557-675-279-860,Conservation Biological Control as an Important Tool in the Neotropical Region.,2022-11-30,2022,journal article,Neotropical entomology,16788052; 1519566x,Springer Science and Business Media LLC,Brazil,German Vargas; Leonardo F Rivera-Pedroza; Luis F García; Simone Mundstock Jahnke,"The history and recent developments of conservation biological control (CBC) in the context of industrialized and small-scale agriculture are discussed from theoretical framework available in the Neotropical region. A historical perspective is presented in terms of the transition of the way pests have been controlled since ancestral times, while some of these techniques persist in some areas cultivated on a small-scale agriculture. The context of industrialized agriculture sets the stage for the transition from chemical pesticides promoted in the green revolution to the more modern concept of IPM and finds in conservation biological an important strategy in relation to more sustainable pest management options meeting new consumer demands for cleaner products and services. However, it also noted that conservation, considered within a more integrative approach, establishes its foundations on an overall increase in floral biodiversity, that is, transversal to both small-scale and industrialized areas. In the latter case, we present examples where industrialized agriculture is implementing valuable efforts in the direction of conservation and new technologies are envisioned within more sustainable plant production systems and organizational commitment having that conservation biological control has become instrumental to environmental management plans. In addition, a metanalysis on the principal organisms associated with conservation efforts is presented. Here, we found that hymenopteran parasitoids resulted in the most studied group, followed by predators, where arachnids constitute a well-represented group, while predatory vertebrates are neglected in terms of reports on CBC. Our final remarks describe new avenues of research needed and highlight the need of cooperation networks to propose research, public outreach, and adoption as strategic to educate costumers and participants on the importance of conservation as main tool in sustainable pest management.",52,2,134,151,Context (archaeology); Agriculture; Scale (ratio); Sustainable agriculture; Biodiversity; Environmental resource management; Sustainable management; Environmental planning; Business; Natural resource economics; Geography; Ecology; Economics; Sustainability; Biology; Cartography; Archaeology,Entomophagous; Large-scale agriculture; Meta-analysis; Natural enemies; Small-scale agriculture,"Animals; Pest Control, Biological/methods; Agriculture/methods; Pest Control; Pesticides; Biodiversity; Predatory Behavior",Pesticides,,https://link.springer.com/content/pdf/10.1007/s13744-022-01005-1.pdf https://doi.org/10.1007/s13744-022-01005-1,http://dx.doi.org/10.1007/s13744-022-01005-1,36449176,10.1007/s13744-022-01005-1,,PMC9709742,0,001-894-765-830-762; 002-146-279-907-499; 002-733-113-417-787; 002-779-923-367-64X; 004-397-373-025-74X; 004-463-858-235-123; 004-588-052-499-153; 004-603-091-428-975; 006-149-488-835-726; 006-829-767-080-45X; 007-159-731-641-426; 007-955-378-732-681; 008-527-639-208-93X; 008-900-920-415-693; 010-341-357-446-610; 010-751-884-189-822; 011-675-349-748-017; 013-507-404-965-47X; 014-999-308-259-276; 015-442-030-243-998; 016-915-033-618-701; 018-616-127-386-254; 019-280-267-824-156; 021-921-934-143-717; 022-730-506-902-312; 023-019-492-520-453; 023-522-143-719-091; 024-217-605-187-153; 027-610-572-829-251; 029-107-953-421-131; 031-214-876-595-079; 032-097-350-120-606; 034-623-027-370-445; 035-385-904-660-379; 035-526-589-357-113; 037-246-370-502-896; 037-502-091-563-880; 038-236-651-313-538; 038-381-994-670-781; 040-460-059-983-776; 040-473-067-186-307; 040-743-369-051-624; 041-036-559-910-665; 041-670-758-129-36X; 043-191-137-115-197; 043-956-730-131-763; 045-627-764-453-192; 048-493-294-205-589; 049-682-538-579-86X; 052-343-210-486-370; 055-527-155-296-771; 056-892-630-404-500; 058-668-625-353-75X; 062-845-134-713-676; 063-475-050-179-550; 064-756-245-181-009; 066-598-265-865-987; 067-100-620-187-750; 067-758-913-993-810; 068-162-327-965-218; 070-573-827-775-961; 072-005-020-083-830; 072-213-153-418-469; 072-632-032-064-824; 073-991-920-255-531; 074-644-759-970-554; 075-030-464-105-117; 075-278-972-843-553; 075-763-219-066-167; 078-213-016-496-098; 078-779-012-584-691; 080-398-398-397-268; 081-957-558-361-489; 082-679-530-489-578; 083-710-623-245-694; 084-184-590-135-286; 084-475-534-522-126; 086-657-002-166-132; 087-049-694-287-513; 088-187-283-140-471; 090-599-838-834-315; 092-469-142-130-114; 094-497-765-462-386; 095-306-995-039-85X; 097-145-405-273-813; 098-500-628-055-354; 099-296-112-538-233; 116-905-373-546-042; 122-855-065-599-403; 124-186-361-180-989; 130-930-837-307-421; 139-505-034-189-88X; 141-948-689-735-276; 144-897-555-264-247; 151-373-151-970-862; 151-882-001-076-692; 152-597-478-301-539; 155-601-408-192-355; 160-321-842-724-056; 164-712-285-101-801; 165-971-901-614-794; 168-136-195-756-401; 169-110-846-301-517; 177-953-790-752-014,21,true,,bronze -188-575-614-395-517,Recent trends in CO2 reduction through various catalytic methods to achieve carbon-neutral goals: A comprehensive bibliometric analysis,2025-02-28,2025,journal article,Frontiers in Energy,20951701; 20951698,Springer Science and Business Media LLC,United States,Xuxu Guo; Hangrang Zhang; Yang Su; Yingtang Zhou,,,,,,Reduction (mathematics); Environmental science; Process engineering; Carbon fibers; Biochemical engineering; Chemistry; Environmental chemistry; Engineering; Computer science; Mathematics; Algorithm; Geometry; Composite number,,,,,,http://dx.doi.org/10.1007/s11708-025-0988-2,,10.1007/s11708-025-0988-2,,,0,001-316-253-824-188; 001-866-915-699-213; 002-830-905-247-565; 003-140-635-117-733; 003-827-015-033-863; 004-050-840-001-024; 004-421-172-672-198; 004-662-359-489-112; 005-023-256-696-51X; 005-106-510-274-181; 005-531-925-737-085; 006-507-749-985-077; 010-365-135-873-162; 010-606-974-669-394; 011-170-515-053-197; 012-044-529-163-812; 016-086-627-266-47X; 016-805-497-645-823; 018-529-517-969-652; 019-297-312-076-11X; 019-748-737-794-766; 020-763-335-982-802; 022-750-437-918-529; 023-640-771-802-993; 023-670-938-566-708; 026-671-443-579-471; 027-450-149-356-493; 027-665-320-460-53X; 034-167-934-955-037; 035-561-902-382-694; 037-177-605-154-704; 037-426-339-293-65X; 041-313-715-963-973; 041-667-325-555-438; 043-460-200-592-168; 045-412-806-923-351; 045-530-625-325-026; 046-723-749-451-478; 049-034-082-146-541; 049-529-811-715-404; 049-664-660-282-825; 049-980-142-485-061; 050-112-966-087-248; 050-698-103-983-873; 050-719-253-861-628; 051-905-317-081-07X; 053-311-448-166-668; 054-041-304-032-213; 056-620-806-301-865; 058-722-581-390-974; 059-019-193-631-512; 059-276-038-153-052; 062-029-771-074-357; 062-912-057-319-217; 064-070-144-404-991; 064-780-260-632-584; 065-608-901-613-968; 066-832-909-756-501; 067-834-567-729-68X; 071-553-674-920-790; 071-622-087-002-545; 072-314-976-114-901; 077-031-493-381-61X; 082-895-047-610-944; 084-186-981-839-255; 084-856-274-479-852; 086-696-225-061-962; 089-791-812-783-542; 095-042-122-652-552; 097-404-190-144-742; 101-406-213-378-093; 102-172-293-181-043; 102-584-160-327-038; 105-519-854-107-732; 106-093-711-711-87X; 106-404-250-062-031; 106-734-709-344-326; 111-442-460-583-167; 113-263-720-623-938; 115-139-515-904-217; 116-447-130-362-075; 117-507-152-026-695; 119-314-210-794-302; 120-333-849-240-510; 124-379-303-801-493; 126-337-178-237-412; 128-141-930-424-258; 128-565-061-062-847; 129-163-041-679-06X; 130-167-707-685-815; 131-244-489-431-085; 131-775-898-703-988; 139-394-715-133-081; 141-770-516-078-794; 143-222-712-540-603; 143-455-536-729-972; 147-662-573-109-235; 148-279-411-472-247; 150-491-738-326-268; 150-949-267-627-057; 151-217-174-229-829; 152-838-413-360-145; 152-918-011-739-013; 153-866-871-916-627; 163-183-197-679-075; 164-024-380-711-895; 165-444-855-078-155; 166-490-683-313-238; 167-635-737-946-964; 175-957-506-433-637; 180-679-699-142-660; 191-824-548-957-333; 193-734-630-786-012; 194-743-439-798-702; 196-816-463-646-386; 196-977-003-426-021,1,false,, -188-667-310-627-356,Text Analytics on Green Economy using Bibliometrix,2024-02-15,2024,journal article,Economics and Sustainability,30466008,Sharia Economic Applied Research and Training (SMART) Insight,,Amelia Tri Puspita,"Environmental damage, global warming and climate change are increasingly serious and frightening, and have caused tremendous negative impacts on the lives of mankind and become a frightening specter for the international community. Environmental damage and socio-environmental crises have been the result of development strategies and policies that are not environmentally friendly and pro-people. The government formulated strategic and operational measures to ""green Indonesia"" through a green economy approach. This study aims to determine the development of green economy research trends published by leading journals on Islamic financial economics. The data analyzed consisted of 1183 indexed research publications. The data is then processed and analyzed using R-studio and biblioshiny applications to determine the text analytic development of green economy research.",1,1,,,Green economy; Government (linguistics); Global warming; Climate change; Economy; Business; Studio; Islam; Political science; Economics; Engineering; Geography; Sustainable development; Ecology; Law; Telecommunications; Philosophy; Linguistics; Archaeology; Biology,,,,,https://journals.smartinsight.id/index.php/ES/article/download/415/394 https://doi.org/10.58968/es.v1i1.415,http://dx.doi.org/10.58968/es.v1i1.415,,10.58968/es.v1i1.415,,,0,,0,true,cc-by-nc,hybrid -188-723-469-664-494,"Global burden of disease for musculoskeletal disorders in all age groups, from 2024 to 2050, and a bibliometric-based survey of the status of research in geriatrics, geriatric orthopedics, and geriatric orthopedic diseases.",2025-02-19,2025,journal article,Journal of orthopaedic surgery and research,1749799x,Springer Science and Business Media LLC,United Kingdom,Fan Jiang; Conglan Lu; Zhen Zeng; Zhongyang Sun; Yang Qiu,"Orthopaedic diseases in the elderly pose a significant disease burden, and the number of research papers on the subject is increasing every year.; The GBD database was used to analyze the global disease burden of musculoskeletal disorders in all age groups from 2024 to 2050. The source for bibliometrics was the WoSCC SCI-E database.; Global disability-adjusted life years (DALYs) for musculoskeletal disorders by age were dominated by those aged 70 years and older, but the rate of change in DALYs between 2024 and 2050 was approximately ± 1%. We performed a descriptive analysis of 164,521 geriatrics articles, and 7155 geriatric orthopedics and geriatric orthopedic articles, and performed clustering, co-citation, collaborative network, and burst citation analyses based on Citespace and VOSviewer. Seven clustering tags containing hot content and 26 burst citation keywords containing hot content were finally targeted.; DALY in older adults over 70 years of age accounts for a significant portion of the disease burden of musculoskeletal disorders. Possible future research hotspots in geriatric orthopedics and geriatric bone diseases include three directions: (1) novel clinical procedures and postoperative management (2) various comorbidities caused by SARS-CoV-2 infections and other pathogens; and (3) effectiveness of Stem Cell Therapy in Clinical Applications and Biological Mechanisms of Stem Cell Therapy.; © 2025. The Author(s).",20,1,179,,Medicine; Orthopedic surgery; Geriatrics; Physical therapy; Disease; Gerontology; Family medicine; Internal medicine; Surgery; Psychiatry,Bibliometrics; Bone diseases; Frontiers prediction; Geriatric; Musculoskeletal disorders,"Humans; Musculoskeletal Diseases/epidemiology; Bibliometrics; Aged; Orthopedics/trends; Geriatrics/trends; Global Burden of Disease/trends; Aged, 80 and over; Male; Disability-Adjusted Life Years; Biomedical Research/trends; Female; Surveys and Questionnaires",,National Natural Science Foundation of China (81600694),,http://dx.doi.org/10.1186/s13018-025-05580-y,39972346,10.1186/s13018-025-05580-y,,PMC11841256,0,002-052-422-936-00X; 004-099-619-105-665; 007-329-625-702-220; 007-609-779-568-251; 011-309-164-943-799; 012-561-360-441-578; 013-507-404-965-47X; 018-117-702-430-658; 019-079-013-186-233; 019-630-218-450-108; 032-119-390-639-394; 032-188-309-776-981; 034-993-257-392-98X; 037-159-235-039-768; 039-741-307-381-797; 046-921-864-681-735; 051-332-866-676-695; 056-648-762-772-730; 069-539-843-224-348; 079-769-767-942-714; 082-204-138-902-381; 090-476-872-676-699; 094-654-891-993-344; 098-214-223-597-369; 116-118-264-825-779; 122-287-642-383-23X; 125-034-264-453-256; 140-270-667-591-731; 141-561-557-562-40X; 146-821-539-546-000; 154-442-976-697-931; 155-906-350-912-096; 158-063-963-605-01X; 158-735-561-818-193; 162-237-173-081-68X; 178-076-282-636-724,1,true,"CC BY, CC0",gold -188-767-113-420-354,Mining and Extractivism Records Data for Bibliometric Analysis (Scopus database 1992-2020),2021-11-02,2021,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Maika Zampier,The dataset file export from scopus database and the dataset file export as bibliometrix file on excel format from biblioshiny.,,,,,Scopus; Geography; Database; Data science; World Wide Web; Political science; Computer science; MEDLINE; Law,,,,,https://zenodo.org/record/5638787,http://dx.doi.org/10.5281/zenodo.5638787,,10.5281/zenodo.5638787,,,0,,0,true,cc-by,gold -188-830-942-052-367,Studies on Dividend Policy: A Bibliometric Analysis,,2022,journal article,Orissa Journal of Commerce,09748482,Orissa Journal of Commerce,,Divya Saini; Priti Sharma,"Dividend is one of the controversial topics in financial management which mean out of earning of management how much is distributed to the shareholders and what percentage is retained in business.The main objective of the study is to provide comprehensive overview of previous studies related with the topic 'Dividend Policy' in context of statistical analysis of published articles/documents around the world.For this purpose, the study employed bibliometric analysis, which was conducted through Bibliometrix library and Biblio-Shiny platform of RStudio.Web of science database was used for collection of data with the keywords ""dividend policy"", ""Dividend payouts"", ""Determinants"" and ""Lintner model"" covering the period of 20 years from 2002 to 2022.The findings of the study depict that in 2011, there was great increment in number of publications and from 2018 the publications are continuously increasing.USA, UK and China are the pre-eminent countries having significant contribution in research on dividend policy.",43,3,85,103,Dividend policy; Econometrics; Dividend; Economics; Finance,,,,,,http://dx.doi.org/10.54063/ojc.2022.v43i03.07,,10.54063/ojc.2022.v43i03.07,,,0,005-355-596-411-50X; 006-195-773-151-38X; 010-613-670-461-91X; 015-396-297-547-726; 015-754-513-271-291; 017-813-623-805-020; 020-398-456-488-998; 022-752-822-968-396; 023-330-528-163-657; 027-247-213-757-248; 038-294-082-527-741; 039-175-752-100-013; 044-663-703-148-807; 054-241-304-102-070; 054-797-053-147-322; 058-927-688-725-876; 060-290-753-855-367; 064-857-655-203-779; 070-205-079-181-316; 078-214-253-888-110; 080-072-066-492-509; 081-456-230-481-860; 090-192-216-740-643; 117-277-304-813-954; 121-082-157-201-724; 127-238-426-242-003; 129-179-041-009-935; 143-584-620-559-313; 152-538-244-990-300; 171-931-522-617-910; 174-662-096-310-129; 184-768-968-131-215,0,true,,bronze -189-197-250-841-168,GABAergic receptors and essential oils in anxiety and depression: a scientometric analysis.,2025-05-22,2025,journal article,Natural product research,14786427; 14786419,Informa UK Limited,United Kingdom,Jaqueline Kappke Zambianchi; Marjorie Benegra,"This review aims to map and analyse scientific production on the effect of essential oils and their isolated compounds on GABAergic receptors with a focus on the treatment of anxiety and depression. Publications were selected from the Web of Science following the PRISMA guidelines from October 1945 to March 2024. Analysis of publication trends, geographic distribution, keywords, and influential articles was carried out using the CiteSpace and Bibliometrix tools. The results indicate that research on the topic is a recent trend, with only eight articles published before 2003 and a significant increase in publications during the SARS-CoV-2 pandemic. The main areas of interest were Medicinal Chemistry, Plant Sciences, and Integrative and Complementary Medicine, with Brazil and China leading the publications. The study also highlights a growing interest in scientifically validating natural therapies for safer and more effective treatment options.",,,1,12,GABAergic; Anxiety; Depression (economics); Neuroscience; Psychology; GABAA receptor; Traditional medicine; Receptor; Essential oil; Medicine; Biology; Chemistry; Psychiatry; Botany; Internal medicine; Economics; Macroeconomics,Complementary therapy; aromatherapy; bibliometric analysis; mental health; neurotransmitters,,,,,http://dx.doi.org/10.1080/14786419.2025.2505610,40402161,10.1080/14786419.2025.2505610,,,0,000-311-511-858-331; 000-445-977-855-400; 001-671-168-342-797; 003-903-047-192-238; 005-209-917-577-450; 005-664-230-397-538; 007-329-625-702-220; 007-450-888-171-024; 010-115-273-004-991; 011-637-417-594-113; 013-253-053-380-121; 017-300-737-144-757; 018-280-532-107-574; 020-602-439-330-06X; 029-442-793-279-639; 036-467-684-800-506; 038-450-259-997-194; 043-558-142-750-126; 045-925-870-390-311; 047-067-877-591-241; 053-060-049-043-86X; 055-989-270-320-147; 056-831-187-860-763; 057-960-279-808-96X; 060-470-094-995-742; 065-010-405-236-060; 066-682-725-907-570; 070-703-029-655-538; 071-218-353-840-054; 073-427-443-303-926; 086-960-547-604-130; 087-062-117-434-380; 090-906-497-750-830; 091-796-676-750-758; 095-442-977-584-631; 104-379-328-700-458; 111-261-080-011-690; 120-840-195-148-77X; 149-241-547-110-969; 154-784-562-847-952; 157-949-107-679-098; 188-656-026-764-798,0,false,, -189-222-773-450-707,University management perspectives: A systematic literature review through bibliometrix,2022-11-01,2022,journal article,Revista Boletín Redipe,22561536,Red Iberoamericana de Pedagogia,,Andrea Mosquera-Guerrero; Edward Enrique Escobar-Quiñonez,"The university is a key actor in the creation of knowledge that must respond to the demands of diferent interest groups that asked pertinent responses and in line with global trends; so, its management has become, over time, a complex activity. Based on the above, this work is presented, which aims to publicize trends in university management through the review of the Web of Science and Scopus databases. The records obtained were analyzed using Graph theory and tools such as Bibliometrix. The results allowed identifying four perspectives: a. technology transfer and university entrepreneurship; b. educational model; c. Change management in academic institutions and d. Interest groups. Through a network analysis, it was determined that the most relevant authors are Henry Etzkowitz, Mario Raposo and G.E. Zborovsky. For its part, the region with the highest production in the subject is the United Kingdom and it is pertinent to note that the research carried out allows us to appreciate that the subject is in the boom phase.",11,11,110,128,Scopus; Subject (documents); Boom; Knowledge management; Work (physics); Entrepreneurship; Sociology; Library science; Political science; Computer science; Public relations; Engineering; Mechanical engineering; MEDLINE; Environmental engineering; Law,,,,,https://revista.redipe.org/index.php/1/article/download/1911/1883 https://doi.org/10.36260/rbr.v11i11.1911,http://dx.doi.org/10.36260/rbr.v11i11.1911,,10.36260/rbr.v11i11.1911,,,0,,0,true,cc-by-sa,gold -189-296-291-277-448,LA INTERCULTURALIDAD EN LA PRODUCCIÓN CIENTÍFICA DE ACADÉMICOS ECUATORIANOS,2022-09-15,2022,journal article,Revista de Ciencias Sociales,22152601; 04825276,Universidad de Costa Rica,,Jorge Mantilla; Frank Mila; Belén Mantilla,"El objetivo del presente artículo es desarrollar una revisión sobre el aporte de la academia ecuatoriana al estudio de la interculturalidad dentro de las bases académicas Scopus y Web of Science, en torno a cuatro puntos: cantidad, impacto, colaboración y temáticas. La metodología implementada consistió en un análisis bibliométrico empleando el paquete bibliometrix en R. El análisis muestra que, dentro de estos espacios, el desarrollo del estudio de la interculturalidad no se encuentra lo suficientemente desarrollado en comparación con su relevancia social. Sin embargo, existen dinámicas y proyecciones de crecimiento, diversificación y generación de espacios colaborativos.",,175,145,157,Humanities; Philosophy,,,,,https://revistas.ucr.ac.cr/index.php/sociales/article/download/52489/52636 https://doi.org/10.15517/rcs.v0i175.52489 https://www.redalyc.org/journal/153/15372615012/15372615012.pdf https://www.redalyc.org/articulo.oa?id=15372615012,http://dx.doi.org/10.15517/rcs.v0i175.52489,,10.15517/rcs.v0i175.52489,,,0,,1,true,cc-by-nc,gold -189-422-517-622-254,Bridging borders and boundaries: the role of new technologies in international entrepreneurship and intercultural dynamics,2024-12-19,2024,journal article,International Entrepreneurship and Management Journal,15547191; 15551938,Springer Science and Business Media LLC,Germany,Silvana Filomena Secinaro; Michele Oppioli; Lara Demarchi; Ota Novotny,,21,1,,,Entrepreneurship; Globalization; International business; Knowledge management; Leverage (statistics); Bridging (networking); Context (archaeology); Emerging technologies; Business; Public relations; Political science; Engineering ethics; Engineering; Computer science; Computer network; Law; Paleontology; Finance; Machine learning; Artificial intelligence; Biology,,,,,,http://dx.doi.org/10.1007/s11365-024-01061-6,,10.1007/s11365-024-01061-6,,,0,001-526-561-468-854; 003-186-717-587-02X; 004-565-736-583-143; 006-094-955-513-772; 006-590-007-311-567; 007-230-303-633-816; 009-932-868-871-220; 011-793-847-542-406; 011-976-896-300-755; 013-507-404-965-47X; 014-129-634-820-525; 014-660-928-011-500; 016-499-968-373-914; 016-853-859-481-106; 017-998-624-346-675; 019-482-610-181-940; 020-659-129-018-369; 021-131-069-914-209; 023-235-714-244-244; 025-960-444-338-981; 026-505-562-660-180; 030-050-495-909-236; 030-621-879-475-955; 031-114-435-244-232; 032-517-326-134-723; 035-641-671-203-459; 035-715-077-218-841; 037-800-944-663-548; 042-388-239-371-813; 044-021-311-595-54X; 045-422-273-148-899; 055-612-597-409-020; 057-252-865-800-55X; 064-671-532-958-092; 067-461-470-339-184; 070-224-004-741-204; 072-396-463-074-037; 077-433-953-684-50X; 077-598-249-628-673; 077-825-282-838-16X; 085-239-944-280-985; 090-474-261-821-827; 090-858-258-375-427; 092-125-028-901-131; 092-898-113-178-763; 093-548-853-249-359; 094-830-887-038-563; 095-720-304-609-184; 098-087-280-636-003; 105-050-688-723-699; 109-166-884-495-806; 113-682-442-621-962; 117-455-760-414-34X; 118-415-868-990-330; 130-000-474-582-959; 130-440-224-490-890; 138-996-910-342-374; 140-359-750-170-971; 140-534-922-839-869; 141-026-656-461-626; 144-131-915-505-368; 144-146-788-200-407; 145-886-604-101-851; 147-484-880-559-771; 147-718-009-878-877; 151-664-027-797-126; 163-619-647-798-667; 168-209-877-163-683; 170-853-169-717-509; 172-540-569-045-030; 174-110-326-973-222; 177-701-248-941-244; 188-038-507-525-327,4,false,, -189-536-468-231-948,Exploring the hybrid organizations debate in the business studies,2025-03-11,2025,journal article,Review of Managerial Science,18636683; 18636691,Springer Science and Business Media LLC,Germany,Asad Mehmood; Stefano Za; Francesco De Luca,"Abstract; This paper intends to explore the debate on hybrid organizations in business studies as business scholars have been increasingly focusing on hybrid organizations in recent times. This study extracted a sample of 370 papers from the Scopus database and performed bibliometric analysis, including descriptive and thematic analyses. The R and Bibliometrix packages are used to perform bibliometric analysis. The descriptive analysis results present the growing interest of business scholars in hybrid organizations research, especially more recently. The thematic analysis results identify eight major topics in the corpus, including hybrid organizations, hybrids, governance, sustainability, social mission, tensions, assembly chain, and hybridity. The future research agenda could be useful for academics to address the gaps highlighted to provide solutions for the efficiency of hybrid organizations.",,,,,Business; Process management,,,,Università degli Studi G. D'Annunzio Chieti Pescara,,http://dx.doi.org/10.1007/s11846-025-00872-3,,10.1007/s11846-025-00872-3,,,0,000-495-052-448-323; 000-505-245-621-395; 002-383-825-785-521; 004-257-758-649-110; 004-719-135-968-258; 005-873-641-536-29X; 006-573-317-687-821; 006-832-004-700-785; 010-170-329-978-579; 010-194-028-604-828; 011-526-846-145-963; 011-899-346-475-773; 012-839-272-189-580; 013-507-404-965-47X; 013-911-226-080-218; 017-750-600-412-958; 022-191-417-894-007; 023-413-572-124-245; 026-178-832-039-373; 027-034-314-552-461; 027-890-201-822-965; 028-238-490-324-434; 029-512-215-879-086; 030-122-724-140-118; 031-960-831-845-876; 033-141-385-121-651; 035-366-248-858-729; 037-475-730-222-839; 039-054-617-459-09X; 041-317-002-181-945; 043-386-395-022-591; 044-024-030-915-598; 044-572-835-445-201; 045-018-966-605-824; 045-610-183-603-331; 045-914-896-967-47X; 046-696-528-627-942; 046-813-930-866-837; 046-992-864-415-70X; 047-134-478-431-993; 049-364-679-999-485; 052-043-643-151-141; 052-742-291-189-615; 052-872-010-507-265; 052-969-498-368-406; 058-588-762-218-781; 058-824-824-686-516; 063-981-512-053-146; 067-116-300-327-52X; 068-856-154-430-94X; 075-303-903-471-612; 080-987-396-259-940; 081-220-734-335-268; 081-379-091-203-337; 085-191-040-025-148; 087-361-933-760-774; 087-446-241-064-551; 091-251-088-563-745; 095-288-999-119-738; 098-165-237-869-400; 107-812-584-444-274; 109-012-311-039-297; 109-176-247-191-411; 111-108-961-746-928; 114-355-576-262-430; 116-829-562-853-680; 119-549-444-584-419; 124-542-121-894-649; 125-122-840-190-731; 129-316-273-531-43X; 129-517-905-137-037; 133-475-458-978-281; 133-974-540-070-13X; 135-951-191-816-546; 137-576-148-942-871; 137-780-473-120-44X; 138-360-231-297-010; 145-217-480-189-661; 146-434-486-183-188; 151-269-647-616-947; 151-318-262-407-683; 156-128-801-122-607; 158-765-637-054-415; 159-110-244-591-69X; 170-745-312-689-080; 172-146-066-198-427; 172-287-606-591-852; 173-353-983-912-518; 183-997-693-223-446; 184-062-612-412-177,0,true,cc-by,hybrid -189-601-608-120-798,Conceptualizing organizational culture and business-IT alignment: a systematic literature review,2022-08-08,2022,journal article,SN Business & Economics,26629399,Springer Science and Business Media LLC,,Marcel R. Sieber; Milan Malý; Radek Liška,"AbstractFor decades, business and information technology alignment has fascinated scholars and practitioners. However, understanding these alignment mechanisms is challenging. The significant role of information technology (IT) in digitalization and agile transformation calls for targeted management of the readiness and capability of IT as an enabler and strategic business partner. This paper assumes that organizational culture is a success factor for business-IT alignment. Therefore, it aims to explore the culture-alignment relationship by the following research questions: What are typical IT management organizational culture characteristics, and how do they contribute to business-IT alignment? The study conducts a systematic literature review. First, after defining the critical terms, it searches the databases indexed in the Web of Science, Scopus, and Google Scholar. Then, the study uses bibliometrics to get quantitative insights into the research topic. Finally, it investigates the key arguments and findings of the selected papers. The analyzed literature depicts the relationship between an IT management culture and business-IT alignment elements. However, the research lacks concrete modeling and conception. This article contributes to a better culture-alignment relationship interpretation and closes a gap in the body of knowledge by combining quantitative and qualitative literature review methods.",2,9,,,Scopus; Knowledge management; Organizational culture; Agile software development; Strategic alignment; Systematic review; Enabling; Bibliometrics; Computer science; Business; Political science; Strategic planning; Public relations; World Wide Web; Psychology; Marketing; Software engineering; MEDLINE; Strategic financial management; Law; Psychotherapist,,,,ZHAW Zurich University of Applied Sciences,https://link.springer.com/content/pdf/10.1007/s43546-022-00282-7.pdf https://doi.org/10.1007/s43546-022-00282-7,http://dx.doi.org/10.1007/s43546-022-00282-7,,10.1007/s43546-022-00282-7,,,0,000-831-262-868-596; 002-479-814-719-461; 005-419-271-447-192; 005-753-801-603-548; 005-796-039-321-468; 006-136-698-460-480; 006-297-091-183-146; 007-191-521-182-022; 008-020-527-252-204; 009-163-803-229-372; 010-488-703-062-342; 012-112-560-950-437; 013-044-866-691-946; 013-507-404-965-47X; 015-179-947-788-927; 015-264-968-994-064; 016-206-736-240-213; 020-829-259-551-144; 022-166-685-764-685; 031-967-119-113-489; 032-277-993-988-159; 039-817-283-589-558; 043-652-467-015-112; 046-904-623-169-12X; 047-535-131-928-703; 050-426-592-797-57X; 053-260-246-901-874; 057-803-697-074-453; 060-081-369-099-543; 060-110-039-971-60X; 062-203-422-352-743; 064-534-120-800-562; 066-709-810-267-499; 069-410-029-911-816; 073-725-849-546-755; 076-309-687-143-879; 076-889-766-139-61X; 083-110-815-666-099; 088-273-808-364-904; 094-344-394-555-948; 094-397-354-080-756; 096-530-276-653-696; 099-714-081-598-151; 109-645-450-864-043; 110-556-780-538-874; 115-559-925-574-098; 129-514-832-413-438; 136-202-828-623-070; 141-026-656-461-626; 143-808-613-360-103; 144-615-031-245-629; 144-867-349-933-449; 146-161-076-654-249; 147-745-162-408-322; 155-327-256-229-892; 161-156-386-041-285; 167-622-482-912-531; 169-557-059-104-750; 183-478-832-005-680,2,true,cc-by,hybrid -189-619-969-870-223,Research landscape and trends of human umbilical cord mesenchymal stem cell-derived exosomes.,2025-05-28,2025,journal article,Stem cell research & therapy,17576512,Springer Science and Business Media LLC,United Kingdom,Desheng Chen; Zeping Chen; Jiabin Yuan; Guanzi Chen; Yutao Chen; Kaiming He; Yongwei Hu; Linsen Ye; Yang Yang,"Human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) have gained significant attention for their potential in cellular regeneration and functional rehabilitation. Nevertheless, the rapid expansion of research in this field makes it challenging for emerging trends and strategic priorities, potentially impeding scientific advancement. This study employs bibliometric analysis to systematically evaluate the research landscape and highlight pivotal research trajectories of hUCMSC-Exos.; Publications on hUCMSC-Exos from 2012 to 2024 were retrieved from the Web of Science Core Collection (WoSCC). Quantitative bibliometric analysis was implemented through integrated utilization of VOSviewer, CiteSpace, and Bibliometrix analytical tools.; China and its institutions led global publication output, with Qian Hui from Jiangsu University identified as the most prolific author. STEM CELL RESEARCH & THERAPY emerged as a high-impact journal in this domain. Current research predominantly focuses on immunomodulation, regenerative medicine, pharmaceutical delivery systems, and clinical model development. Future research directions are expected to explore angiogenesis, spinal cord injury, and immunomodulation.; This study maps the evolving landscape of hUCMSC-Exos research, emphasizing its applications in regenerative medicine. By synthesizing current and emerging paradigms, these findings provide insights into therapeutic potential, novel mechanisms, and pathways for clinical translation.; © 2025. The Author(s).",16,1,259,,Microvesicles; Mesenchymal stem cell; Umbilical cord; Stem cell; Cord lining; Biology; Cell biology; Wharton's jelly; Immunology; Endothelial stem cell; Adult stem cell; microRNA; Genetics; Gene; In vitro,Angiogenesis; Bibliometric analysis; Exosomes; Human umbilical cord; Immunomodulation; Mesenchymal stem cell; Spinal cord injury,Humans; Exosomes/metabolism; Mesenchymal Stem Cells/metabolism; Umbilical Cord/cytology; Regenerative Medicine,,National Natural Science Foundation of China (82103448); National Natural Science Foundation of Chin (81972286); Natural Science Foundation of Guangdong Province (2023A1515010322); National Key Research and Development Program of China (2024YFA1107200); Guangzhou Science and Technology Basic and Applied Basic Research Project (2023A04J1802),,http://dx.doi.org/10.1186/s13287-025-04379-2,40437553,10.1186/s13287-025-04379-2,,PMC12121053,0,000-584-664-954-74X; 001-619-316-035-572; 001-678-362-690-914; 002-052-422-936-00X; 007-150-419-208-432; 007-407-550-564-468; 009-090-794-088-808; 009-730-357-414-727; 013-167-502-537-307; 013-507-404-965-47X; 014-398-662-212-194; 017-150-546-182-290; 021-325-258-442-648; 021-814-553-602-023; 027-695-355-587-108; 029-239-144-938-67X; 032-501-528-804-573; 034-389-736-141-976; 036-229-643-769-916; 038-123-967-208-899; 038-921-988-478-640; 039-156-825-806-532; 043-314-038-291-192; 047-084-330-572-631; 049-903-187-516-504; 051-225-173-466-632; 051-863-767-403-440; 052-404-156-432-73X; 052-553-011-179-883; 054-033-577-798-142; 057-105-470-577-429; 060-129-642-143-470; 061-345-483-855-51X; 062-130-425-730-127; 064-400-499-357-900; 064-772-145-608-976; 066-980-376-945-223; 071-742-076-623-190; 075-648-901-095-741; 075-828-400-275-275; 078-686-927-704-660; 082-792-545-242-994; 086-633-377-405-631; 089-218-687-734-87X; 092-303-031-787-551; 094-671-581-632-548; 100-766-137-621-145; 102-752-627-483-190; 106-025-940-457-014; 108-908-805-545-961; 112-203-142-154-162; 119-218-289-720-591; 167-611-506-594-82X; 181-596-272-224-635; 182-647-054-747-52X; 184-197-402-250-77X; 188-636-786-650-496,0,true,"CC BY, CC0",gold -189-899-846-386-385,bibliometrixData: Bibliometrix Example Datasets,2020-12-10,2020,dataset,CRAN: Contributed Packages,,The R Foundation,,Massimo Aria,,,,,,Computer science,,,,,,http://dx.doi.org/10.32614/cran.package.bibliometrixdata,,10.32614/cran.package.bibliometrixdata,,,0,,0,false,, -189-944-541-155-260,Strategic Development Associated with Branding in the Tourism Sector: Bibliometric Analysis and Systematic Review of the Literature between the Years 2000 to 2022,2022-08-10,2022,journal article,Sustainability,20711050,MDPI AG,Switzerland,Campo Elías López-Rodríguez; Jorge Alexander Mora-Forero; Ana León-Gómez,"This study aims to identify research trends associated with the development of brand management in the tourism sector. To this end, bibliometric analysis has been carried out, using the R Core Team 20201-Bibliometrix software, on the scientific production, the most influential countries, authors, and journals, and the co-occurrence of keywords in the 1421 articles published to date in the Scopus database. This analysis was then complemented with a systematic qualitative evaluation using the PRISMA technique. The results obtained show the trend and impact of the literature published to date and the established and emerging research groups. Furthermore, they identify that research procedures related to brand communities, co-branding, brand architecture, positioning, and brand research in the tourism sector need to be strengthened. Therefore, this study identifies key research questions in a way that provides a planning framework for future research in this field.",14,16,9869,9869,Scopus; Tourism; Brand management; Systematic review; Business; Marketing; Knowledge management; Political science; Computer science; MEDLINE; Law,,,,Corporación Universitaria Minuto de Dios-UNIMINUTO,https://www.mdpi.com/2071-1050/14/16/9869/pdf?version=1660126499 https://doi.org/10.3390/su14169869 https://riuma.uma.es/xmlui/bitstream/10630/31464/1/sustainability-14-09869.pdf https://hdl.handle.net/10630/31464,http://dx.doi.org/10.3390/su14169869,,10.3390/su14169869,,,0,001-687-347-758-006; 002-052-422-936-00X; 004-987-437-751-610; 007-306-408-944-395; 008-751-578-389-883; 008-933-034-782-238; 009-503-814-166-897; 010-248-539-793-780; 010-659-660-711-229; 011-506-562-004-909; 012-019-394-854-311; 013-507-404-965-47X; 014-674-006-993-082; 015-142-570-351-32X; 018-232-833-960-521; 018-327-065-596-289; 019-544-888-210-92X; 024-235-854-809-135; 025-768-219-827-922; 028-111-695-019-988; 030-255-692-425-205; 031-337-844-430-026; 034-920-719-139-261; 036-462-880-509-211; 038-440-137-637-853; 038-722-420-269-844; 040-460-483-991-302; 042-065-394-421-992; 044-765-193-747-670; 044-808-566-509-681; 048-348-308-626-253; 049-035-339-763-559; 049-492-215-600-647; 051-330-976-845-219; 052-446-451-313-448; 052-706-000-817-960; 052-727-615-785-195; 053-651-630-577-915; 054-157-429-654-766; 054-253-020-066-686; 054-500-966-915-656; 057-656-344-703-798; 058-720-345-434-083; 060-418-519-979-409; 068-607-272-671-448; 076-797-342-155-837; 078-411-837-846-208; 083-287-287-108-301; 087-618-496-577-672; 089-241-293-864-917; 095-966-182-413-422; 099-353-398-709-429; 102-599-629-583-779; 102-683-742-697-841; 110-040-579-183-509; 116-801-743-648-403; 120-547-683-840-682; 123-352-216-911-188; 132-750-399-770-671; 132-791-139-608-900; 135-989-658-682-267; 136-101-167-916-112; 149-436-599-384-662; 156-187-704-981-59X,5,true,,gold -190-042-550-087-602,Health and Urbanism: General Statistics in Literature and Research Trends,,2022,journal article,International Journal of Innovative Studies in Sociology and Humanities,24564931,ARC Publications,,Nassima Khenchouche; Labii Belkacem; Amel Benzaoui,"This research aims to determine the overall trend in the subject, the core publications, the significant subjects, and the ongoing research thematic.Data preprocessing was conducted in order to match the data with the Bibliometrix utility suite's criteria. METHODOLOGYThe methodology is based on the documents extracted from Scopus platform, and the most relevant statistics are shown in Table 1.The main steps are as follow:",7,7,25,29,Urbanism; Statistics; Data science; Geography; Regional science; Computer science; Mathematics; Archaeology; Architecture,,,,,,http://dx.doi.org/10.20431/2456-4931.0707003,,10.20431/2456-4931.0707003,,,0,,0,true,,bronze -190-057-765-613-421,Co-authorship and co-occurrences analysis using Bibliometrix R-package: a casestudy of India and Bangladesh,2019-08-21,2019,,,,,,Samir Kumar Jalal,"Research collaboration between India and Bangladesh based on research output of 1156 papers jointly produced by bothcountries were retrieved from Web of Science for the period of 1991 to 2017.The collaboration network on co-authorshipand co-occurrences was build using BibliometrixR package. Top ten keywords have been plotted to show the subject trendsin general. VOSviewer was used to build network maps to know the collaborative zones with respect to authors, subjectsand keywords. The study shows that the major collaborations were in medical science followed by agriculture and biologicalsciences. The verification of Lotkas’s Law was made using lotka() function in Bibliometrix R-package. The finding of thestudy shows that Lotka’s law is still valid for the co-authorship data at the international level.",66,2,57,64,Data science; Subject (documents); R package; Network on; International level; Co authorship; Medical science; Web of science; Computer science; Function (engineering),,,,,http://op.niscair.res.in/index.php/ALIS/article/view/22404/465477091 http://nopr.niscair.res.in/handle/123456789/50075 http://nopr.niscair.res.in/bitstream/123456789/50075/1/ALIS%2066%282%29%2057-64.pdf http://14.139.47.23/index.php/ALIS/article/view/22404,http://op.niscair.res.in/index.php/ALIS/article/view/22404/465477091,,,2971495944,,0,,9,false,, -190-274-296-984-203,Data from Web of science and Scopus in Brazil dentistry (2010-2020): bibliometric analysis with bibliometrix (version 2),,,,,,,,Ana Paula Calabrez; Brianda Sigolo,,1,,,,Engineering; Library science; Bibliometric analysis; Web of science; Scopus,,,,,https://data.mendeley.com/datasets/pykrddv5cp,http://dx.doi.org/10.17632/jcgr99zmvg.1,,10.17632/jcgr99zmvg.1,3181931767,,0,,0,false,, -190-651-607-071-964,"Mapping the Research Landscape of Chatbots, Conversational Agents, and Virtual Assistants in Business, Management, and Accounting: A Bibliometric Review",2023-12-15,2023,journal article,Qubahan Academic Journal,27098206,QUBAHAN,,Manigandan L; Sivakumar Alur,"This bibliometric review aims to map the research landscape of chatbots, conversational agents, and virtual assistants in the business, management, and accounting of the subject area. The review begins by examining the growth of research in this area over time, revealing an increasing interest in the application of chatbots, conversational agents, and virtual assistants in business, management, and accounting contexts. This study aims to contribute to the field of chatbot research by conducting a bibliometric analysis of chatbot, conversational agent and virtual assistant papers available in the Scopus databases. A comprehensive analysis of 378 articles was performed utilizing the Bibliometrix software package. The keywords ""Chatbot"", ""conversational agent"" and “virtual assistant” emerged as the most frequently employed terms in the majority of publications. It explores the various domains within which these technologies have been studied, including customer service, marketing, human resources, and financial management.",3,4,502,513,Chatbot; Knowledge management; Computer science; Service (business); World Wide Web; Data science; Business; Marketing,,,,,https://journal.qubahan.com/index.php/qaj/article/download/252/124 https://doi.org/10.58429/qaj.v3n4a252,http://dx.doi.org/10.58429/qaj.v3n4a252,,10.58429/qaj.v3n4a252,,,0,,2,true,cc-by-nc-nd,gold -190-735-652-551-471,Data-Driven Visualization of the Dynamics of Antimicrobial Peptides in Cell Death.,2025-05-28,2025,journal article,Probiotics and antimicrobial proteins,18671314; 18671306,Springer Science and Business Media LLC,United States,Dan Hou; Jiatong Zhao; Mingshi Guo; Xinran Zhang; Shuiqing Yu; Jiayue Li; Tymour Forouzanfar; Qing Zhang; Janak L Pathak,,,,,,Antimicrobial; Visualization; Dynamics (music); Computational biology; Antimicrobial peptides; Biology; Programmed cell death; Computer science; Data mining; Genetics; Microbiology; Psychology; Apoptosis; Pedagogy,Antimicrobial peptides; Bibliometrics; Cancer; Cell death; Mechanism; Visualization analysis,,,the Medical Science and Technology Research Fund Project of Guangdong Province (A2023225); the Research Capacity Enhancement Program of Guangzhou Medical University (2024SRP154); National Natural Science Foundation of China (32301129),,http://dx.doi.org/10.1007/s12602-025-10578-3,40434503,10.1007/s12602-025-10578-3,,,0,001-415-758-404-713; 004-910-515-961-328; 005-415-963-086-246; 005-445-747-492-298; 005-522-690-579-734; 005-662-355-266-268; 005-918-359-303-456; 006-650-341-728-589; 007-585-028-274-443; 008-834-147-316-213; 011-407-548-436-250; 013-675-762-597-34X; 014-282-709-612-124; 019-738-106-393-844; 021-752-929-469-355; 022-724-174-294-179; 023-790-109-541-93X; 024-293-224-099-082; 024-812-967-800-900; 025-522-019-541-33X; 026-075-624-131-210; 026-684-868-478-767; 029-123-910-228-235; 029-627-686-765-958; 029-722-432-402-271; 029-900-573-622-808; 030-470-009-593-119; 030-531-549-622-116; 031-843-928-672-147; 032-079-325-477-946; 034-430-500-514-141; 036-183-145-190-310; 036-300-105-811-16X; 036-390-683-402-108; 037-356-213-836-232; 038-559-015-281-092; 038-841-943-907-763; 039-107-922-286-54X; 040-051-674-557-771; 041-148-602-793-991; 041-565-129-213-601; 042-927-350-549-261; 043-394-763-265-512; 043-474-267-479-247; 047-147-483-051-824; 051-424-351-367-488; 051-772-495-806-559; 052-841-648-941-800; 053-316-852-745-584; 054-109-219-140-71X; 061-148-771-092-796; 063-892-238-079-524; 065-642-721-389-89X; 066-648-739-916-532; 068-265-312-568-65X; 070-968-084-438-257; 072-291-809-689-055; 078-072-705-305-342; 080-478-836-563-992; 082-844-937-734-439; 085-047-441-665-553; 090-476-872-676-699; 093-444-341-026-753; 094-023-367-211-309; 094-111-820-737-369; 098-800-090-193-089; 104-031-097-388-411; 105-334-354-697-00X; 106-696-604-888-496; 109-055-005-155-556; 113-716-945-720-332; 117-046-905-062-617; 119-807-902-587-078; 120-522-162-601-327; 123-171-580-094-601; 123-409-262-765-34X; 125-578-305-173-177; 128-211-021-193-457; 133-772-006-467-529; 134-184-268-150-754; 141-009-332-743-999; 143-569-496-194-859; 152-092-565-930-284; 157-698-178-970-743; 185-754-932-309-746; 199-919-818-722-909,0,false,, -190-750-733-593-994,Worldwide Trend Analysis of Psycholinguistic Research on Code Switching Using Bibliometrix R-tool,2023-11-30,2023,journal article,Sage Open,21582440,SAGE Publications,United States,Zilong Zhong; Lin Fan," The study of bilingualism and multilingualism has gained increasing prominence in the context of globalization. As a result, research on code switching has garnered growing attention, leading to a substantial number of published papers in recent decades. To gain insights into the current status and potential trends of psycholinguistic research on code switching, this study conducted a bibliometric analysis of 1,293 articles focusing on code switching from 1968 to 2022. The analysis was performed using bibliometrix, a bibliometric software package in R. The results of the analysis indicated that code switching between English and other languages, the role of inhibition ability, and the processing mechanisms of highly proficient bilinguals were prominent hot topics in the field of code-switching research. Additionally, the processing of grammatical gender, bilingual language production, and plurilingualism were identified as potential emerging research trends. By presenting a macroscopic landscape of research on code switching, this study aims to provide readers with a comprehensive overview and serve as a beneficial reference for researchers in this field. ",13,4,,,Code-switching; Multilingualism; Neuroscience of multilingualism; Context (archaeology); Field (mathematics); Code (set theory); Globalization; Computer science; Psychology; Linguistics; Political science; Geography; Programming language; Mathematics; Pedagogy; Pure mathematics; Law; Philosophy; Archaeology; Set (abstract data type); Neuroscience,,,,Double FirstClass Disciplines Project of Beijing Foreign Studies University,https://journals.sagepub.com/doi/pdf/10.1177/21582440231211657 https://doi.org/10.1177/21582440231211657,http://dx.doi.org/10.1177/21582440231211657,,10.1177/21582440231211657,,,0,000-029-295-727-898; 013-285-232-306-193; 013-507-404-965-47X; 013-746-687-009-282; 020-788-880-626-468; 027-338-979-744-129; 027-570-606-739-454; 030-170-759-335-78X; 030-493-294-229-552; 031-100-423-521-709; 032-494-959-922-261; 036-287-086-845-490; 036-849-390-395-297; 036-865-341-785-344; 037-119-112-124-878; 042-170-927-636-051; 044-776-532-451-668; 048-811-228-609-594; 050-135-389-147-504; 051-549-937-131-308; 054-460-868-406-176; 057-023-817-524-539; 057-711-455-342-007; 061-456-053-369-580; 069-574-635-170-422; 069-679-119-446-219; 070-091-661-228-340; 073-433-475-585-578; 078-358-171-091-629; 079-297-377-937-327; 080-034-870-593-557; 082-196-274-184-41X; 088-867-181-759-985; 092-444-990-495-764; 093-618-573-812-136; 099-944-654-279-224; 101-279-973-617-49X; 103-099-870-117-788; 103-455-260-906-358; 103-717-282-553-781; 113-819-869-409-64X; 117-776-317-298-484; 117-912-405-838-077; 119-960-531-866-211; 122-681-030-485-142; 128-817-030-860-510; 129-731-505-551-922; 140-262-799-287-600; 143-806-762-438-323; 158-764-399-486-612; 161-772-448-156-07X; 173-958-791-977-036; 179-402-003-411-942; 182-816-699-193-32X; 190-541-342-555-762; 197-239-706-122-050; 198-770-957-959-675,6,true,cc-by,gold -190-945-754-913-635,The Virtual Teaching in Statistics Course in Higher Education: A Bibliometric Analysis and Systematic Literature Research,,2024,journal article,International Journal of Information and Education Technology,20103689,EJournal Publishing,,Carlos A. Alvarado-Silva,"The research presents a bibliometric review aimed at understanding the most effective educational practices for teaching statistics in a virtual setting. It identifies the primary scopes, achievements, and challenges associated with this recent approach. To achieve this, the study explores articles published in journals indexed in databases like Scopus and Web of Science between 2017 and 2023. These articles offer recommendations based on evidence-backed pedagogical practices. Out of the scrutinized articles, 50 studies aligning with inclusion criteria were analyzed. These studies were subjected to a bibliometric approach and systematic literature research supported by the R bibliometrix software. This software was utilized to identify various research trends. Based on the study results, the analysis grouped teaching methods that exhibit greater efficacy in the virtual learning of the statistics.",14,2,333,344,Course (navigation); Statistics; Computer science; Mathematics education; Data science; Psychology; Mathematics; Engineering; Aerospace engineering,,,,,https://www.ijiet.org/vol14/IJIET-V14N2-2055.pdf https://doi.org/10.18178/ijiet.2024.14.2.2055,http://dx.doi.org/10.18178/ijiet.2024.14.2.2055,,10.18178/ijiet.2024.14.2.2055,,,0,,1,true,,gold -191-024-797-859-747,Insights on Debt Behaviour: A Bibliometric Analysis,,2024,journal article,European Economic Letters,,Science Research Society,,Raman Rohilla; Shweta Anand,"This article conducts a comprehensive analysis of debt behaviour research, examining its evolving trends, influential authors, intellectual structure, collaborative networks, and thematic evolution. Through a systematic literature review and bibliometric analysis utilizing the Bibliometrix R-package, a dataset of 138 meticulously selected documents from the Scopus database is analysed. Findings reveal a notable increase in research productivity, with concentrations in finance, consumer studies, and marketing disciplines. Scientific mapping uncovers three knowledge structures: conceptual, thematic, and intellectual. This comprehensive examination offers invaluable insights into the scholarly landscape of debt behaviour research, serving as a vital resource for researchers and policymakers alike.",,,,,Debt; Bibliometrics; Data science; Computer science; Business; Economics; Data mining; Macroeconomics,,,,,https://www.eelet.org.uk/index.php/journal/article/download/1355/1166 https://doi.org/10.52783/eel.v14i1s.1355,http://dx.doi.org/10.52783/eel.v14i1s.1355,,10.52783/eel.v14i1s.1355,,,0,,0,true,,bronze -191-047-765-912-322,"Social Entrepreneurship, Value Creation, and Sustainability",2023-12-21,2023,book chapter,"Research Anthology on Business Law, Policy, and Social Responsibility",,IGI Global,,Raihan Taqui Syed; Dharmendra Singh; David Philip Spicer,"This chapter presents an in-depth examination and analysis of published literature indexed in Scopus database on social entrepreneurship, sustainability, and value creation. A descriptive bibliometric analysis coupled with content analysis is presented incorporating citations included in Scopus' multi-disciplinary database over the last 20 years. Two software packages, VOS Viewer and Bibliometrix R, were employed to probe the research questions and create visualizations of the bibliometric networks. The interconnected and multifaceted nature of the research field is demonstrated, thematic evolution is illustrated, and emerging clusters are identified. Findings suggest that the research on social entrepreneurship, sustainability, and value creation has been pioneered by USA followed by India and other countries. Also, further steps need to be undertaken to encourage and enable cross-border international collaboration to draw learning together from different national and regional contexts.",,,1433,1448,Scopus; Sustainability; Entrepreneurship; Thematic analysis; Discipline; Value (mathematics); Knowledge management; Value creation; Content analysis; Field (mathematics); Political science; Data science; Regional science; Sociology; Social science; Qualitative research; Computer science; Ecology; MEDLINE; Machine learning; Law; Biology; Mathematics; Pure mathematics,,,,,,http://dx.doi.org/10.4018/979-8-3693-2045-7.ch073,,10.4018/979-8-3693-2045-7.ch073,,,0,004-165-766-721-911; 008-503-021-110-600; 010-091-998-488-563; 013-422-282-868-950; 013-507-404-965-47X; 019-699-637-726-16X; 019-848-752-466-128; 020-095-383-008-392; 023-527-718-075-323; 025-613-233-950-568; 032-161-831-571-882; 033-014-253-880-814; 034-245-699-998-862; 034-848-852-823-034; 039-101-432-893-817; 043-978-415-056-502; 044-273-117-734-340; 063-923-109-075-518; 064-319-450-193-281; 075-216-272-257-429; 075-636-596-178-023; 076-048-730-218-555; 076-362-237-070-679; 077-235-952-619-805; 079-746-444-437-105; 082-981-095-520-012; 087-039-175-403-499; 087-880-193-343-581; 091-665-851-820-988; 093-079-508-738-670; 093-122-684-921-168; 094-996-584-032-447; 109-214-920-628-164; 111-348-209-308-455; 116-545-813-640-686; 123-380-982-614-72X; 130-602-202-936-694; 138-856-335-101-827; 139-364-430-420-645; 140-176-565-691-036; 164-566-134-146-268; 176-753-588-630-192; 183-158-161-350-500; 192-135-671-580-685,0,false,, -191-538-317-117-188,برمجيات رسم الخرائط الببليومترية والسيانتومترية والتصور العلمي : دراسة تقويمية مقارنة,2023-01-01,2023,journal article,المجلة العلمية للمکتبات والوثائق والمعلومات,26362872,Egypts Presidential Specialized Council for Education and Scientific Research,,متولي الدکر,"This study deals with scientific visualization and bibliometric mapping software.The study aims to introduce different types of these tools, shed light on their characteristics and features, and show the best software currently available.First, the study listed the scientific visualization, bibliometric and scientometric mapping software.This list included nine main factors, which are Operating systems, user interfaces, bibliographic data sources and databases, bibliometric data formats, preprocessing options and methods, bibliometric networks, units of analysis, bibliometric measurements and network normalization measurements, bibliometric mapping techniques, methods of analysis, scientific visualization techniques, documentation, technical support, and availability.In addition, the study applied bibliometric analysis, using the scientific visualization techniques available in the software explored in the study -highlights each of the distinctive features and similar features.The study concluded that Bibliometrix R is the best software, and it comes in the first place according to the criteria presented.The Bibliometrix R was followed by the SciMAT tool.While Citan and HistCite software were at the bottom; Because of their lack of analysis methods and bibliometric networks, the study also found that Bibliometrix R, SciMAT, CiteSpace, Sci2 Tool, VOSviewer, NWB Tool, VantagePoint, and Bibexcel can be identified as more complete tools.",5,13.1,6,62,Philosophy,,,,,https://jslmf.journals.ekb.eg/article_271214_249864940368fe63e3a63320fc64153a.pdf https://doi.org/10.21608/jslmf.2021.80368.1078,http://dx.doi.org/10.21608/jslmf.2021.80368.1078,,10.21608/jslmf.2021.80368.1078,,,0,,0,true,cc-by-nc,gold -192-150-549-706-200,Global research hotspots and trends on microplastics: a bibliometric analysis.,2023-05-18,2023,journal article,Environmental science and pollution research international,16147499; 09441344,Springer Science + Business Media,Germany,Mehri Davtalab; Steigvilė Byčenkienė; Ieva Uogintė,,30,49,107403,107418,Microplastics; Bibliometrics; Environmental science; Geography; Library science; Computer science; Ecology; Biology,Bibiometrix; Bibliometric; Microplastic; Trend analysis; VOSviewer,Microplastics; Plastics; Bibliometrics; Data Mining,Microplastics; Plastics,European Union's Horizon Europe research and innovation programme (No. 101057497),,http://dx.doi.org/10.1007/s11356-023-27647-1,37199843,10.1007/s11356-023-27647-1,,,0,000-212-938-217-054; 002-052-422-936-00X; 002-067-124-530-257; 002-455-036-646-780; 002-908-855-141-179; 006-168-092-340-704; 006-983-719-812-180; 007-942-405-154-58X; 008-481-854-173-820; 009-886-164-567-12X; 010-977-574-758-278; 011-410-640-528-999; 012-089-141-855-459; 012-871-233-926-760; 013-388-698-372-100; 013-507-404-965-47X; 013-757-318-579-347; 014-118-602-419-127; 015-406-104-507-346; 015-738-042-591-044; 016-910-131-064-340; 017-221-654-812-558; 017-628-631-303-392; 019-500-880-568-375; 020-198-283-785-217; 020-223-005-057-756; 020-306-342-770-716; 020-623-029-497-847; 020-651-592-714-191; 021-833-007-405-544; 023-215-832-467-627; 023-841-019-437-52X; 023-897-067-820-550; 025-538-290-556-279; 026-958-984-507-436; 030-223-203-306-090; 031-168-749-270-998; 031-398-409-070-109; 031-759-890-655-939; 032-700-705-954-110; 033-495-754-245-544; 034-072-952-522-364; 035-655-485-951-493; 035-940-519-618-801; 036-935-882-457-459; 037-069-104-684-039; 037-547-706-552-58X; 037-785-881-896-180; 045-674-521-851-18X; 046-477-814-791-110; 048-704-672-327-231; 050-826-254-993-722; 051-033-850-751-689; 052-407-424-312-608; 052-583-833-387-558; 053-649-709-050-865; 053-768-168-301-546; 054-484-150-994-470; 057-013-248-145-942; 058-602-330-353-267; 058-795-586-455-949; 062-987-320-055-674; 064-400-499-357-900; 064-645-004-940-973; 066-327-011-101-288; 068-612-539-956-650; 069-016-845-736-344; 069-298-060-127-774; 073-412-482-990-704; 075-406-808-714-761; 076-028-042-179-339; 077-959-345-883-309; 078-646-382-585-094; 086-795-008-541-488; 089-273-298-972-913; 096-582-427-759-506; 101-236-493-947-14X; 105-240-147-119-410; 114-714-671-125-532; 119-296-720-065-875; 123-836-241-652-65X; 125-613-104-984-484; 126-313-839-593-953; 127-854-257-877-663; 131-335-313-231-50X; 139-572-476-439-508; 159-449-324-657-831; 170-264-160-809-049; 175-048-062-280-319; 179-364-725-316-82X,14,false,, -192-207-076-532-742,The impact of surgical randomised controlled trials on the management of FAI syndrome: a citation analysis.,2023-10-10,2023,journal article,"Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA",14337347; 09422056,Wiley,Germany,Hassaan Abdel Khalik; Darius L Lameire; Lily J Park; Olufemi R Ayeni,,31,12,6006,6019,Impact factor; Medicine; Sample size determination; Randomized controlled trial; MEDLINE; Citation; Clinical trial; Science Citation Index; Surgery; Internal medicine; Library science; Statistics; Mathematics; Political science; Computer science; Law,Citation analysis; Femoroacetabular impingement; Fragility index; Hip arthroscopy; Knowledge translation,Humans; Femoracetabular Impingement/surgery; Arthroscopy; Journal Impact Factor; Europe; Treatment Outcome; Hip Joint/surgery; Randomized Controlled Trials as Topic,,,,http://dx.doi.org/10.1007/s00167-023-07608-4,37816919,10.1007/s00167-023-07608-4,,,0,000-646-307-850-898; 000-924-183-805-215; 001-659-939-595-345; 002-293-719-537-621; 004-433-550-508-191; 004-979-496-444-020; 006-984-888-662-587; 007-116-385-566-223; 007-817-449-057-762; 011-574-496-386-500; 012-426-249-491-305; 012-678-965-959-248; 013-507-404-965-47X; 017-778-625-927-928; 020-720-008-331-682; 023-007-496-750-186; 023-244-405-144-578; 023-812-000-754-127; 025-506-202-223-946; 025-895-056-356-127; 027-329-597-121-44X; 029-998-532-086-12X; 031-056-855-501-837; 035-485-785-168-717; 040-088-615-960-21X; 042-095-934-668-994; 043-050-664-685-90X; 044-560-093-398-937; 045-843-883-326-491; 047-134-968-607-672; 051-061-297-337-906; 052-547-519-377-337; 054-030-406-009-766; 054-378-138-235-43X; 056-510-804-625-818; 058-020-474-348-272; 058-952-276-503-761; 060-242-034-183-852; 067-609-845-059-145; 071-009-384-648-910; 078-179-558-136-015; 083-527-443-128-874; 083-717-214-136-202; 086-022-856-645-760; 088-858-640-974-891; 092-456-434-422-466; 102-862-018-888-755; 103-843-974-911-874; 104-948-309-220-35X; 108-891-242-650-806; 112-397-456-010-290; 115-236-108-351-437; 132-249-546-386-970; 157-204-101-857-387; 163-865-890-487-897; 182-612-019-519-409,4,false,, -192-532-724-595-83X,BiblioBoP: a promising scope of bottom of the pyramid related research through a bibliometric approach,,2022,journal article,International Journal of Bibliometrics in Business and Management,20570538; 20570546,Inderscience Publishers,,Debadrita Panda; Sabyasachi Mukhopadhyay; Tej Narayan Shaw; Subhadip Banerjee,"The emergent field of bottom of the pyramid (BoP) is rapidly evolving in terms of academic publications. It has become imperative to keep track of the publications to find out various information like authors, country, emerging themes, research gap and further scope of research. This paper proposes a bibliometric approach and begins with identifying 1,113 articles on the global perspective from the Scopus database. With the help of Biblioshiny, a web interface for Bibliometrix package, publication evolution over time, identification of current research areas and potential direction of future research and many more have been identified for a refined result of 1,029 papers. This mixed review method involving the quantitative bibliometric analysis and qualitative content analysis indicates a sustainable picture of current research and noteworthy future scope for both global and Indian perspectives. As a whole, this study aims to provide a robust roadmap about the BoP literature.",2,1,75,75,Scope (computer science); Scopus; Top-down and bottom-up design; Data science; Field (mathematics); Perspective (graphical); Pyramid (geometry); Computer science; Bibliometrics; Bottom of the pyramid; Management science; Political science; Engineering; World Wide Web; Business; Marketing; MEDLINE; Mathematics; Software engineering; Programming language; Physics; Optics; Artificial intelligence; Pure mathematics; Law,,,,,,http://dx.doi.org/10.1504/ijbbm.2022.122316,,10.1504/ijbbm.2022.122316,,,0,,0,false,, -192-713-818-233-605,Global status and trends in gout research from 2012 to 2021: a bibliometric and visual analysis.,2023-01-20,2023,journal article,Clinical rheumatology,14349949; 07703198,Springer Science and Business Media LLC,Germany,Yu Wang; Wenjing Li; Hao Wu; Yu Han; Huanzhang Wu; Zhijian Lin; Bing Zhang,"Gout is the most common inflammatory arthritis with an increasing prevalence and incidence across the globe. We aimed to provide a comprehensive and systematic knowledge map of gout research to determine its current status and trends over the past decade.; Publications on gout research were obtained from the Web of Science Core Collection (WOSCC) database. Bibliometric R, VOSviewer, and Citespace were employed to analyze the eligible literature.; A total of 5535 publications concerning gout research between 2012 and 2021 were included. Most publications and citations both numerically came from China. The strongest international cooperation belonged to the USA. The University of Auckland was the most productive institution with a leading place in research collaboration. The prime funding agency was the National Natural Science Foundation of China. Most papers were published in Clinical Rheumatology. Annals of the Rheumatic Diseases achieved the highest number of citations, H-index and IF, which showed the most excellent comprehensive strength. The individual author with the most paper authorship was Dalbeth Nicola with 241 publications and 46 H-index. Keywords and co-citation analysis discovered that pathological mechanism remains the future hotspot in gout research. It may involve gout connection with gut microbiota, NLRP3 inflammasome, xanthine oxidase, and urate-transporter ABCG2. In addition, besides metabolic diseases, the relationship between gout and heart failure may need more attention.; This study clarified the current status and research frontier in gout over the past decade, which would provide valuable research references for later researchers. Key Points •We disclosed the current status and frontier directions of gout over the past 10 years worldwide. •We identified future hotspots of gout research, including gout connection with gut microbiota, NLRP3 inflammasome, xanthine oxidase, and urate-transporter ABCG2. •We discovered that the relationship between gout and heart status would be the research frontier.; © 2023. The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR).",42,5,1371,1388,Medicine; Gout; Rheumatology; Internal medicine; Medical physics,Arthritis; Gout; NLRP3 inflammasome,"Humans; Inflammasomes; NLR Family, Pyrin Domain-Containing 3 Protein; Uric Acid; Xanthine Oxidase; Gout/epidemiology; Bibliometrics","Inflammasomes; NLR Family, Pyrin Domain-Containing 3 Protein; Uric Acid; Xanthine Oxidase",National Natural Science Foundation of China (82104475); National Natural Science Foundation of China (U20A20406); Natural Science Foundation of Beijing Municipality (7212178),https://link.springer.com/content/pdf/10.1007/s10067-023-06508-9.pdf https://doi.org/10.1007/s10067-023-06508-9,http://dx.doi.org/10.1007/s10067-023-06508-9,36662336,10.1007/s10067-023-06508-9,,PMC9852810,0,002-052-422-936-00X; 002-210-744-580-692; 002-362-222-675-814; 002-907-566-604-259; 003-370-248-642-670; 007-983-286-472-008; 010-168-316-482-221; 010-815-863-278-498; 011-149-429-406-850; 011-877-286-271-21X; 013-507-404-965-47X; 014-558-918-425-493; 014-778-910-057-731; 016-363-557-224-882; 016-772-470-710-244; 021-242-338-483-366; 021-506-256-138-151; 022-969-780-173-911; 026-395-112-558-483; 027-656-910-892-282; 028-126-170-522-97X; 028-529-617-038-284; 028-870-569-976-290; 029-280-540-718-294; 030-302-433-236-863; 030-376-101-345-133; 031-179-499-477-235; 035-211-011-856-964; 036-039-775-940-511; 036-656-168-693-890; 037-090-330-168-821; 038-033-952-704-188; 038-411-537-841-690; 040-267-315-220-694; 040-546-958-887-486; 042-533-810-796-676; 043-292-742-029-206; 046-910-611-793-487; 047-928-253-559-018; 051-135-554-801-685; 051-700-517-234-334; 053-130-129-479-541; 056-426-226-149-95X; 060-772-108-554-563; 061-877-295-914-153; 062-574-483-854-643; 063-162-122-534-025; 073-096-863-686-376; 073-600-923-404-052; 075-574-897-032-393; 076-187-735-477-900; 076-836-050-435-414; 077-215-642-522-436; 084-653-055-375-172; 085-872-037-633-277; 101-549-244-470-296; 101-752-490-869-458; 103-510-887-727-491; 105-123-328-460-252; 110-932-014-359-304; 114-694-110-658-480; 116-347-391-306-815; 147-521-670-530-559; 163-486-425-258-546; 175-757-260-369-666,12,true,,bronze -192-755-388-684-822,Tendencias de la enseñanza y entrenamiento de Six Sigma (SS): un análisis bibliométrico.,2024-05-01,2024,journal article,"Dilemas contemporáneos: Educación, Política y Valores",20077890,Asesorias y tutorias para la Investigacion Cientifica en la Educacion Puig-Salabarria S.C.,,Omar Celis-Gracia; Jorge Luis García-Alcaraz; Fabiola Hermosillo-Villalobos,"Este articulo presenta una revisión bibliométrica de 1545 documentos identificados en base de datos Scopus y que tratan sobre la enseñanza y entrenamiento de Seis Sigma (SS) en países a nivel mundial. Se utiliza el software VOSviewer y Bibliometrix para analizar los documentos. Los resultados indican que las investigaciones sobre SS son muy extensas, sin embargo, aun hace falta analizar más la importancia de la enseñanza en SS y su impacto en la industria y la sociedad. Se concluye que SS debe ser más analizada para ayudar a las empresas a enfrentar los retos globales que presentan y contribuir positivamente en el aspecto económico y social.",,,,,Political science; Humanities; Art,,,,,,http://dx.doi.org/10.46377/dilemas.v11i3.4102,,10.46377/dilemas.v11i3.4102,,,0,,0,true,,gold -192-824-907-907-538,African Journal of Biological Sciences,2024-07-15,2024,journal article,African Journal of Biological Sciences,16874870; 23145501,Institute for Advanced Studies,,,"Bovine Colostrum (BC) is the first milk cows produce after giving birth.BC contains essential nutrients required by neonates.These nutrients may be potentially beneficial to humans.This review aims to establish the nature of the published evidence, thereby detailing the use of bovine colostrum in supplement manufacturing.This scoping review focuses on evidence in the literature related to the manufacturing process, efficacy or efficiency, and nutritional composition of bovine colostrum supplements.The Scopus database was searched to identify all relevant full-text literature published in English.The methodology used to conduct this scoping review is the JBI method.The scoping review follows the Preferred Reporting Items for Systematic Reviews and Meta-analysis extension for Scoping Reviews (PRISMA-Scr) reporting method.Bibliometric analyses were conducted on the included publications.An R-based software package called bibliometrix was used to perform the Bibliometric analyses.The findings from the studies revealed that there has been an increase in annual scientific production on the topic, highlighting an increase in interest in the subject.The thematic map generated using bibliometrix software using the author's keywords revealed that some of the keywords were in the motor themes quadrant, indicating higher relevance and coherence of the research topics.The review's findings also revealed high research output from developed countries and low research output from developing countries.The results indicate thatEgypt produced the highest research output in the selected publications on the African continent, with four documents on the topic.The research fields that made the largest contribution to the topic under review were medicine, agriculture, and nursing, with 29.4%, 21.2%, and 18.2% contributions, respectively.The results indicate that the countries with the highest frequency of collaboration in the selected literature are the US, the UK, and Australia.Insights from the scoping review were used to develop a Research Agenda to address the research gaps within the research area.Quality Standards,",6,12,,,Scopus; Systematic review; Library science; Computer science; MEDLINE; Political science; Law,,,,,https://www.afjbs.com/uploads/paper/8fae1d4c731aafef2d3176542e7cffc9.pdf https://doi.org/10.48047/afjbs.6.12.2024.3954-3968,http://dx.doi.org/10.48047/afjbs.6.12.2024.3954-3968,,10.48047/afjbs.6.12.2024.3954-3968,,,0,,0,true,cc-by,hybrid -193-608-049-172-300,Estudio bibliométrico sobre la felicidad laboral,2024-05-07,2024,journal article,Revista Gestión de las Personas y Tecnología,07185693,University of Santiago of Chile,,Jorge Alejandro Sánchez Henríquez; Javiera Alejandra Veliz Alcaino,"The article aims to analyze the scientific production in relation to happiness at work, showing the impact that this topic has on the scientific production in the Web of Science database. The methodology used to develop the research is bibliometric, the study covered from 2007 to the present. The Bibliometrix and VOSviewer software were used for data processing; 160 documents were finally reviewed in depth, considering only open access articles. The analysis of these documents included authors, sources, keywords, citations, H index and co-citations, among other aspects. Over time, the topic of happiness has been relevant and has been analyzed from different areas and perspectives, however, in terms of happiness at work, its study has slowly increased, despite the relevance that, according to Most of the authors analyzed have this theme in the organizations of the modern world.",17,49,30,30,Psychology,,,,,https://www.revistas.usach.cl/ojs/index.php/revistagpt/article/download/6093/26004895 https://doi.org/10.35588/yh4dkd02,http://dx.doi.org/10.35588/yh4dkd02,,10.35588/yh4dkd02,,,0,,0,true,cc-by-nc,gold -193-705-238-606-31X,Technology-Enhanced Education of English in Ubiquitous Context,2022-05-27,2022,book chapter,Advances in Educational Technologies and Instructional Design,23268905; 23268913,IGI Global,,Céline Meyran-Martínez; Jorge Bacca-Acosta; Josef Buchner,"This chapter deals with the evolution of research in English language education linked to applied technologies, under the ubiquitous paradigm, over the past 60 years (1960-2021). Descriptive (authors, articles, citations) and relational (co-words, co-citation, co-author) bibliometric indicators are used to trawl a database of 5219 documents from Scopus. Bibliometrix R package, biblioshiny, and VOSviewer analysis are handled to draw the trends of this area around the world. The findings demonstrate that main topics passed from ESL to technology education to the technology integration for learning processes. The trending topics for the field include mobile-assisted language learning, WhatsApp (and other social media), gamification, virtual reality, and online learning. Well-developed topics include motivation, writing, and teacher education. Future research directions are also discussed. ",,,244,274,Computer science; Context (archaeology); Scopus; Social media; Field (mathematics); Citation; Multimedia; World Wide Web; Data science; Geography; Political science; Mathematics; Archaeology; MEDLINE; Pure mathematics; Law,,,,,,http://dx.doi.org/10.4018/978-1-7998-8852-9.ch012,,10.4018/978-1-7998-8852-9.ch012,,,0,001-158-413-373-857; 003-753-933-394-319; 005-700-816-639-958; 007-005-501-218-807; 009-520-752-110-429; 011-880-287-384-985; 013-507-404-965-47X; 013-524-854-219-241; 013-683-191-846-68X; 014-424-383-958-90X; 019-152-336-162-496; 020-450-699-393-868; 020-720-570-099-630; 021-628-110-485-615; 024-446-176-751-383; 025-299-898-978-319; 025-587-157-749-152; 029-922-148-744-81X; 034-768-039-318-254; 035-486-354-888-370; 035-723-715-484-74X; 037-550-015-414-716; 041-809-973-429-692; 043-677-063-217-720; 044-664-442-822-916; 046-084-416-314-194; 046-992-864-415-70X; 048-420-666-542-82X; 052-877-202-385-429; 057-501-891-430-18X; 059-802-781-736-817; 060-180-669-364-656; 061-346-068-942-872; 062-614-311-304-876; 067-051-571-339-341; 069-871-954-206-198; 069-953-959-102-186; 070-744-373-327-913; 077-839-723-364-201; 079-947-113-308-801; 081-008-572-958-033; 082-677-611-060-491; 086-449-252-284-143; 090-009-664-150-622; 094-256-984-697-153; 095-171-647-808-186; 097-741-033-137-52X; 098-039-481-873-949; 099-811-875-723-537; 107-593-041-205-181; 115-959-837-976-647; 120-691-730-123-907; 122-955-278-694-322; 131-932-304-832-843; 141-096-124-334-670; 141-834-424-400-811; 141-928-753-139-965; 143-123-567-082-197; 143-875-130-007-110; 145-218-498-183-094; 151-777-456-670-706; 160-286-317-282-99X; 168-036-345-097-619; 170-222-773-446-118; 172-890-723-997-751; 198-439-929-573-396,1,false,, -194-397-504-477-878,Preprocesamiento de publicaciones acerca de indentidad digital descentralizada y autgobernada.,2022-01-01,2022,dataset,Figshare,,,,Roberto Pava,Referencias en formato bibtex obtenidas de las bases de datos Scopus y WoS. Preprocesamiento con el paquete bibliometrix,,,,,Humanities; Computer science; Philosophy,,,,,https://figshare.com/articles/dataset/Referencias_sobre_SSI_obtenidas_en_formato_bibtex/19579492/4,http://dx.doi.org/10.6084/m9.figshare.19579492.v4,,10.6084/m9.figshare.19579492.v4,,,0,,0,true,cc-by,gold -194-822-666-374-26X,Bibliometric overview of the Tehran Lipid and Glucose Study (TLGS) publications from 2000 to 2022.,2024-02-13,2024,journal article,Journal of diabetes and metabolic disorders,22516581,Springer Science and Business Media LLC,United Kingdom,Fahimeh Rezaeizadeh; Arash Ghazbani; Mohsen Nouri; Zahra Bahadoran; Mohammad Javad Mansourzadeh; Davood Khalili,"The present study was conducted to analyze the publications of the Tehran Lipid and Glucose Study (TLGS) and assess its scientific productions during the last 23 years.; The required data were retrieved from the Scopus database. The advanced search was chosen, and the search query included terms related to the TLGS. Search and retrieval of data were conducted on August 30, 2022. Bibliometric indicators have been used at three levels in this research including the level of documents, journals, and authors. Also, the knowledge structure of this set was analyzed at the level of social structure and the level of conceptual structure. Data analysis and visualizations was performed using Bibliometrix and VOSviewer software.; A total of 870 documents related to the TLGS have been indexed in the Scopus from 2000 to 2022, and 1148 authors have participated in the relevant studies. 66.4% of the TLGS documents were published in journals with Q1 subject area quartiles. There was an annual growth rate of 20% and average citations per document of 16.5. There was a co-authorship per document of 5.6 and an international co-authorship of 8.7%. According to the co-occurrence network for keywords, the most common areas in the TLGS published documents were nutrition, epidemiologic issues, cardiometabolic-related biomarkers, diabetes, hypertension, lifestyle variables and genetic studies.; Over the past 23 years, the TLGS has successfully addressed a wide range of inquiries pertaining to cardiometabolic and nutritional issues in Iran. The remarkable achievements of the TLGS act as a catalyst, advocating for the planning and implementation of additional cohort studies that specifically focus on non-communicable diseases within the Iranian population.; © The Author(s), under exclusive licence to Tehran University of Medical Sciences 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.",23,1,343,351,Scopus; Quartile; Medicine; Computer science; Data science; Information retrieval; MEDLINE; Internal medicine; Biology; Confidence interval; Biochemistry,Bibliometrics; Cohort; Iran; Network Analysis; Non-communicable diseases; TLGS,,,,,http://dx.doi.org/10.1007/s40200-024-01392-9,38932887,10.1007/s40200-024-01392-9,,PMC11196460,0,002-052-422-936-00X; 005-407-529-409-030; 010-920-253-779-062; 013-405-164-102-896; 013-507-404-965-47X; 013-918-254-072-508; 015-012-648-780-891; 017-246-733-579-919; 023-752-653-688-874; 026-581-966-196-956; 027-087-151-003-028; 027-946-191-091-010; 030-184-036-846-700; 030-986-584-715-802; 044-946-884-511-838; 049-391-379-302-694; 053-294-443-458-934; 063-623-067-747-624; 071-790-732-842-903; 081-361-153-973-121; 094-678-296-899-448; 099-316-217-535-376; 105-545-658-839-679; 110-688-493-043-160; 116-870-703-189-918; 129-767-068-923-955,0,true,,unknown -194-864-369-577-955,Panorama mundial de la producción científica sobre actos de habla: un análisis bibliométrico,2023-03-13,2023,journal article,Lingüística y Literatura,24223174; 01205587,Universidad de Antioquia,,Dennis Arias-Chávez; Teresa Ramos-Quispe; Julio Efraín Postigo-Zumarán,"Este estudio tiene por objetivo caracterizar la producción científica mundial sobre actos de habla en las bases de datos Scopus y Web of Science desde enero del año 2000 a junio del año 2022. Para el análisis bibliométrico se utilizaron los programas Bibliometrix R, Publish or Perish v. 8.1 y VOSwiever. Los resultados evidencian una mayor producción en Scopus, en tanto que los picos de mayor producción se presentaron en los años 2010 y 2015. A partir del año 2017 se observa un crecimiento constante de la producción sobre el tema.",44,83,207,232,Scopus; Humanities; Political science; Geography; Philosophy; MEDLINE; Law,,,,,https://revistas.udea.edu.co/index.php/lyl/article/download/353027/20810832 https://doi.org/10.17533/udea.lyl.n83a09,http://dx.doi.org/10.17533/udea.lyl.n83a09,,10.17533/udea.lyl.n83a09,,,0,002-703-287-364-50X; 003-475-331-111-724; 006-185-667-220-805; 007-312-474-688-992; 008-253-009-955-716; 009-520-064-805-139; 010-442-924-794-711; 017-979-580-124-005; 021-187-636-167-119; 024-372-742-746-37X; 026-281-257-215-603; 031-392-033-416-96X; 046-593-273-185-860; 057-508-692-072-174; 058-069-624-556-702; 059-806-326-055-567; 060-056-950-048-403; 068-097-609-796-063; 070-123-378-552-341; 075-329-675-400-155; 078-390-392-111-304; 082-244-539-407-29X; 088-223-689-434-547; 088-464-443-363-141; 092-731-473-315-229; 096-755-970-102-445; 114-564-882-368-701; 119-240-836-523-476; 121-094-910-229-611; 124-154-675-458-385; 124-204-330-582-105; 128-151-589-923-692; 139-397-315-068-43X; 146-699-130-409-266; 155-877-518-423-924; 169-371-812-479-590; 174-028-470-166-924; 174-158-716-358-324; 175-403-532-481-304,1,true,,gold -195-034-430-556-314,The Impact of Emerging Blockchain Trends on Supply Chain Management,2025-02-06,2025,journal article,Operations Research Forum,26622556,Springer Science and Business Media LLC,,Kadim Lahcen Nadime; Jamal Benhra; Rajaa Benabbou; Salma Mouatassim,,6,1,,,Blockchain; Supply chain management; Supply chain; Business; Computer science; Computer security; Marketing,,,,,,http://dx.doi.org/10.1007/s43069-025-00418-z,,10.1007/s43069-025-00418-z,,,0,001-050-299-995-614; 003-386-087-564-363; 003-391-736-587-204; 004-559-654-372-907; 008-092-872-335-265; 009-702-535-612-809; 013-507-404-965-47X; 014-114-452-853-877; 016-008-231-623-959; 022-368-266-043-379; 023-136-876-227-590; 025-583-549-076-198; 026-015-100-353-117; 027-396-885-561-116; 027-438-102-209-259; 027-847-208-120-049; 029-577-061-727-393; 030-573-966-607-238; 030-629-968-184-152; 034-290-793-012-003; 036-159-145-686-834; 040-738-513-767-891; 042-394-228-997-686; 046-247-660-528-323; 047-137-989-285-629; 052-115-167-317-998; 052-856-094-303-322; 056-834-791-399-700; 057-798-161-513-127; 060-345-256-979-997; 061-673-833-732-556; 062-582-942-080-836; 063-520-050-120-452; 064-400-499-357-900; 067-603-686-199-089; 068-436-818-000-15X; 070-734-210-302-27X; 071-176-890-544-418; 073-367-928-088-898; 074-456-796-365-929; 076-940-050-434-198; 081-059-886-555-309; 081-709-460-993-194; 081-841-229-004-70X; 082-991-111-534-721; 086-583-029-287-517; 089-141-590-296-129; 090-754-045-510-625; 097-248-646-916-092; 097-726-257-528-858; 099-993-498-730-415; 104-293-356-166-443; 104-627-194-782-83X; 112-441-868-142-762; 120-107-471-244-45X; 125-738-624-124-604; 132-110-553-582-287; 132-938-654-390-313; 136-150-362-535-340; 141-599-725-641-830; 147-615-134-088-477; 148-069-352-519-758; 148-854-919-216-293; 151-936-335-067-965; 153-776-398-993-993; 154-664-739-812-40X; 158-873-273-790-945; 163-832-278-432-012; 166-493-462-848-515; 171-115-818-447-150; 193-949-771-071-334; 196-973-525-727-78X; 198-399-850-777-472,0,false,, -195-623-199-693-409,Trends in the applications of artificial intelligence in fatty liver diseases.,2025-05-02,2025,journal article,Hepatology international,19360541; 19360533,Springer Science and Business Media LLC,India,Tian-Ao Xie; Li-Li Liufu; Hui-Jin Chen; Hao-Lin Chen; Xin-Ting Hou; Xuan-Rui Wang; Meng-Yi Han; Yu-Kai Shan; Rui-Jing Shen; Zhong-Yu Wu; Shi-Jie Li; Sarun Juengpanich; Win Topatana,,,,,,Hepatology; Medicine; Colorectal surgery; Fatty liver; Abdominal surgery; Internal medicine; Artificial liver; Gastroenterology; General surgery; Liver failure; Disease,Artificial intelligence; Computer-assisted; Data visualization; Diagnosis; Digital health; Fatty liver; Fatty liver alcoholic; Image processing; Medical informatics applications; Non-alcoholic fatty liver disease; Precision medicine,,,"Zhejiang Provincial Natural Science Foundation of China (No.LQ22H030003); Fundamental Research Funds for the Central Universities (No. 2021FZZX005-21); National Natural Science Foundation of China (No. W2433188); The Youth Development Fund Program of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine (QNPY23041)",,http://dx.doi.org/10.1007/s12072-025-10827-1,40312600,10.1007/s12072-025-10827-1,,,0,002-279-396-497-344; 003-881-360-243-148; 012-397-276-954-395; 019-924-218-904-281; 023-342-097-126-958; 026-536-713-961-442; 028-343-246-831-623; 036-768-534-547-161; 037-259-456-549-727; 039-267-018-354-228; 042-177-873-089-014; 060-446-077-592-132; 063-611-961-368-866; 072-877-180-742-979; 075-761-407-688-095; 090-874-152-872-943; 100-063-268-794-475; 109-288-778-234-878; 109-934-286-369-139; 139-861-180-153-464; 168-201-691-817-590; 183-480-895-446-240; 183-954-945-653-005,0,false,, -195-714-943-970-894,Mapping the Scientific Landscape of Metaverse Using VOSviewer and Bibliometrix,2023-01-26,2023,conference proceedings article,2023 20th Learning and Technology Conference (L&T),,IEEE,,Tayeb Brahimi; Hala Haneya,"The concept of the Metaverse has gained increasing attention as advances in virtual and augmented reality (AR) technologies have enabled the creation of immersive and interactive virtual environments. However, most of these studies remain independent and only a few studies attempted to investigate their relationships. To analyze key trends in Metaverse research and conduct a thorough bibliometric analysis, we used VOSviewer and Bibliometrix, R-tool package on the Scopus database. Our co-occurrence analysis revealed that the hot topics are related to virtual reality, augmented reality, the Internet of Things, and blockchain, and there are potential areas for future research, such as privacy, security, and education in the Metaverse. In addition, our analysis identified the most active countries and institutions in the field, the top subject areas, as well as potential gaps in the literature that could be explored in future research. This study provides valuable insights into Metaverse research and can help guide future research in this field.",,,8,13,Metaverse; Computer science; Augmented reality; Field (mathematics); Subject (documents); Data science; Virtual reality; Scopus; The Internet; Human–computer interaction; World Wide Web; Mathematics; MEDLINE; Political science; Pure mathematics; Law,,,,Effat University,,http://dx.doi.org/10.1109/lt58159.2023.10092363,,10.1109/lt58159.2023.10092363,,,0,002-052-422-936-00X; 013-507-404-965-47X; 014-877-079-909-769; 019-819-261-965-237; 031-378-521-348-344; 046-096-656-702-960; 046-992-864-415-70X; 049-391-379-302-694; 076-991-409-556-862; 086-044-580-403-791; 094-934-030-263-960; 096-922-821-221-948; 113-324-298-927-667; 122-827-252-276-011; 143-936-693-364-687; 146-195-168-128-102; 188-798-445-030-83X,2,false,, -196-478-365-533-59X,Public procurement from the triple bottom line lens: the identification of sustainability criteria from the international literature review,2024-05-22,2024,journal article,"Environment, Development and Sustainability",15732975; 1387585x,Springer Science and Business Media LLC,Netherlands,André Luiz Trajano dos Santos; Augusto da Cunha Reis,,27,5,9805,9840,Triple bottom line; Procurement; Sustainability; Identification (biology); Lens (geology); Line (geometry); Business; Environmental planning; Engineering; Environmental science; Marketing; Petroleum engineering; Ecology; Mathematics; Biology; Geometry,,,,,,http://dx.doi.org/10.1007/s10668-023-04343-1,,10.1007/s10668-023-04343-1,,,0,000-170-377-609-097; 001-183-586-928-392; 001-278-927-154-500; 001-723-896-842-257; 002-299-659-668-335; 003-912-159-242-361; 003-913-247-444-363; 004-119-347-253-79X; 006-428-673-648-203; 006-752-031-573-996; 007-094-782-136-505; 007-197-683-666-481; 007-689-627-152-604; 007-891-659-237-986; 009-115-430-796-633; 009-312-863-359-191; 009-605-400-403-677; 009-901-134-662-153; 010-275-480-252-771; 010-506-995-388-331; 012-657-002-620-37X; 013-507-404-965-47X; 014-885-635-116-189; 015-632-132-978-255; 015-956-225-240-154; 016-433-934-779-930; 016-638-671-320-712; 017-185-412-824-120; 018-462-901-872-536; 018-594-480-326-67X; 020-089-182-354-896; 020-188-689-108-428; 021-475-068-670-926; 025-247-129-157-482; 025-461-276-396-499; 027-673-912-514-052; 027-690-220-065-414; 028-628-959-321-892; 030-924-159-392-156; 030-980-239-255-254; 031-477-177-450-553; 033-757-100-878-921; 034-217-267-887-087; 034-600-684-728-898; 034-742-752-579-083; 035-567-264-182-90X; 035-791-985-903-216; 036-647-570-894-717; 037-743-824-826-607; 038-523-996-988-364; 038-799-013-170-834; 040-571-260-292-928; 040-976-375-068-390; 041-893-176-899-91X; 042-521-387-737-119; 044-007-630-422-733; 045-632-923-939-584; 045-710-806-011-040; 046-818-967-852-837; 047-381-523-792-471; 048-037-701-677-614; 048-977-103-666-982; 049-368-030-095-236; 049-391-379-302-694; 049-742-975-506-994; 057-045-521-656-919; 057-203-529-312-767; 057-786-442-917-269; 057-788-765-379-37X; 059-796-688-579-505; 059-912-335-216-720; 060-637-665-851-438; 061-469-687-627-628; 063-376-424-110-117; 063-816-896-682-486; 064-484-011-425-705; 064-886-230-173-802; 065-301-535-142-484; 065-498-508-457-984; 066-388-202-939-816; 066-599-295-413-345; 066-835-819-431-563; 068-178-781-627-186; 068-687-382-492-953; 070-080-189-245-484; 070-665-150-453-490; 072-218-234-488-242; 074-997-381-109-079; 075-157-928-449-54X; 075-727-185-607-886; 076-930-955-826-074; 077-428-378-531-753; 078-089-169-776-220; 078-698-173-142-769; 079-620-328-028-837; 080-239-837-257-93X; 083-945-316-842-030; 088-476-710-477-10X; 088-660-939-640-403; 089-013-278-849-749; 089-213-748-412-311; 089-795-622-859-751; 090-325-224-340-048; 092-336-059-289-889; 092-446-553-954-44X; 094-456-615-104-857; 095-662-264-964-583; 096-077-077-428-485; 096-275-249-693-240; 096-434-106-882-787; 096-604-650-018-123; 097-836-110-592-967; 098-526-770-989-612; 099-040-449-101-652; 099-281-708-915-843; 099-295-281-698-428; 101-183-123-436-178; 102-572-334-108-946; 103-413-143-719-494; 103-595-590-319-417; 104-515-684-325-678; 104-523-547-706-941; 106-345-868-120-080; 107-189-270-126-693; 110-946-161-028-860; 113-715-695-970-499; 134-590-842-248-355; 134-783-948-200-246; 137-072-431-754-05X; 143-634-034-207-123; 145-185-651-936-550; 146-205-823-020-429; 156-724-445-162-936; 160-973-041-883-966; 166-386-029-534-271; 168-291-110-939-437; 168-686-727-672-062; 170-075-116-790-19X; 178-357-487-459-03X; 179-610-327-751-720; 186-022-896-019-874; 196-578-128-773-723,1,false,, -196-500-942-871-037,Evaluating the impact of the IMO's Energy Efficiency Design Index: A bibliometric analysis,2024-10-07,2024,journal article,"Journal of International Maritime Safety, Environmental Affairs, and Shipping",25725084,Informa UK Limited,,Mohan Anantharaman; Abdullah Sardar; Rabiul Islam; Vikram Garaniya,"The term ""Energy Efficiency Design Index"" (EEDI) was coined by the International Maritime Organisation and was established as one strategy for reducing greenhouse gas emissions from ships. The purpose of this article is to conduct a bibliometric analysis of the research papers published in the past two decades on the implementation process of EEDI. This study utilizes the Scopus database, renowned for its extensive collection of scientific papers. Moreover, to analyse and visualise the data, the bibliometric software tools VOSviewer, Bibliometrix, and Harzing's Publish or Perish have been used. These tools facilitated the assessment of the research output in this bibliometric study. This article provides insight into research done by scholars globally and shows the contemporary topic trends related to the improvement of EEDI in the maritime world.",8,4,,,Index (typography); Environmental science; Computer science; World Wide Web,,,,,,http://dx.doi.org/10.1080/25725084.2024.2408697,,10.1080/25725084.2024.2408697,,,0,000-401-399-498-338; 001-353-523-965-128; 002-374-607-454-770; 003-067-679-121-605; 008-244-713-340-446; 009-994-246-147-282; 011-016-085-779-960; 011-339-444-667-87X; 012-719-137-140-067; 013-305-706-750-268; 014-247-384-677-312; 019-203-411-027-399; 026-584-635-258-60X; 026-728-127-200-962; 026-866-236-868-940; 028-454-964-047-27X; 030-439-226-618-815; 030-657-198-357-923; 031-248-248-089-306; 033-127-677-566-360; 034-624-681-242-776; 034-810-748-404-493; 035-292-136-057-557; 038-805-541-352-752; 039-394-749-206-992; 039-648-730-398-67X; 050-341-538-426-548; 054-307-538-220-204; 054-903-712-198-980; 057-017-869-210-91X; 057-524-753-006-454; 059-670-655-899-154; 064-669-093-494-026; 068-542-846-888-159; 078-519-675-502-086; 081-064-796-462-981; 087-326-736-111-27X; 087-521-636-002-520; 089-875-507-737-003; 091-571-372-315-119; 097-278-048-789-318; 099-514-457-305-091; 108-807-554-499-602; 121-845-069-091-45X; 123-321-274-979-541; 127-570-772-679-149; 139-920-418-535-647; 151-796-983-505-933; 153-207-497-144-356; 167-799-899-163-808; 174-601-699-461-883; 185-269-377-800-384; 185-625-688-987-391; 187-481-876-070-911; 191-030-414-684-910,1,true,"CC BY, CC BY-NC",gold -196-554-625-311-064,The contribution of the University of São Paulo to the scientific production on climate change: a bibliometric analysis,2024-07-09,2024,journal article,Discover Sustainability,26629984,Springer Science and Business Media LLC,,Thais Diniz Oliveira; Tailine Corrêa dos Santos; Jéssica Weiler; Alexandre de Oliveira e Aguiar; Carolina Cristina Fernandes; Luciana Ziglio,"AbstractThis paper evaluates how the contribution of scientific publications on climate change from the University of São Paulo (USP) evolved between 1989 and 2022. The study conducted a bibliometric analysis of 2874 research articles collected from the Web of Science and Scopus databases to explore main trend topics and reveal influential journals and collaboration networks using the Bibliometrix software. The study shows an increasing and more significant temporal publication distribution from 2010 onwards. Based on the author’s affiliations, results indicate that the most important partnerships are national (67%), while the international co-authorships are predominantly with research collaborators of the Global North (North America and Europe). Several papers published in the period are in high-impact factor journals, evidence on climate change from USP. Environmental services, Atlantic Forest, Tropical Forest, Amazon, biodiversity, and Land use are the hotspot research topics to which USP researchers contribute. The evolution of three thematic groups was identified: (i) physical science, (ii) causes and effects, and (iii) strategies, discussed in themes such as organic matter, deforestation, and mitigation, respectively. This research is helpful to get insights into the current research development trends, to show the broadness of the scientific production, and the importance of the USP role in the climate change theme. Ultimately, it provides valuable information for further studies and suggests the possibility of advancing the research agenda on climate change with the Global South.; Graphical Abstract",5,1,,,Climate change; Production (economics); Geography; Regional science; Library science; Political science; Computer science; Economics; Geology; Oceanography; Macroeconomics,,,,USP Sustainability Program of the Superintendence of Environmental Management,,http://dx.doi.org/10.1007/s43621-024-00301-7,,10.1007/s43621-024-00301-7,,,0,006-468-750-642-558; 008-877-237-125-306; 009-597-474-544-459; 010-145-963-895-178; 013-507-404-965-47X; 019-067-494-722-704; 032-045-521-616-776; 033-686-729-717-281; 037-542-651-729-129; 038-167-027-744-055; 041-060-137-087-55X; 043-839-588-378-34X; 044-461-658-338-197; 044-558-398-320-126; 044-971-180-072-43X; 045-422-273-148-899; 048-801-162-637-867; 052-688-764-896-586; 053-359-308-050-455; 062-311-216-868-528; 064-432-056-837-901; 070-386-921-171-781; 070-545-073-050-172; 073-239-050-209-340; 076-831-095-221-564; 078-717-310-772-849; 085-227-545-039-803; 101-315-960-217-441; 101-971-619-361-496; 104-408-149-987-203; 108-593-309-589-144; 109-134-193-854-076; 110-884-632-108-648; 146-271-076-213-635; 154-129-723-591-177; 156-030-569-372-568; 169-206-334-922-623; 169-526-358-302-288; 173-118-823-456-904; 174-962-395-007-482; 176-334-491-054-225; 176-350-617-108-891; 179-166-587-560-412; 193-636-068-986-738,0,true,cc-by,gold -196-962-174-103-559,Energy decentralization scholarly development: A bibliometric study using Bibliometrix R Studio (1982-2024),,2025,journal article,ECONOMICS AND POLICY OF ENERGY AND THE ENVIRONMENT,22807659; 22807667,Franco Angeli,Italy,null Sajida,"Energy decentralization has become an increasingly significant issue in recent years, while the world has searched for sustainable, resilient, and fair energy solutions. This study contributes to mapping the development and identifying the key underlying themes of energy decentralization by using a systematic bibliometric analysis of the scholarly literature. Based on 65 English-language publications from 1982 to 2024, this study uses the Scopus database to show how these have systemically evolved from broad concepts of decentralization and governance to focused discussions on energy decentralization, blockchain, and renewable energy integration. A trend in the research focus has been increasing interest in what digital technologies and policy frameworks mean for the future with regard to decentralized energy systems. It also established that there is a high degree of global collaboration in this area of research, although this is centered around the United Kingdom. Thematic analysis identifies established motor themes related to blockchain and energy policy, specialized niche themes, and new areas of study. It contributes to an important overview of the state of the art on energy decentralization but equally puts forward some critical gaps and future directions, thereby offering valuable insight for researchers, policymakers, and practitioners concerned with the advancement of decentralized energy systems.",,1,65,106,,,,,,,http://dx.doi.org/10.3280/efe2025-001003,,10.3280/efe2025-001003,,,0,000-088-238-234-464; 000-227-580-537-273; 001-561-471-228-009; 003-149-621-175-837; 003-935-505-548-93X; 005-471-858-637-321; 006-142-709-049-859; 006-700-598-473-916; 007-230-672-492-270; 010-908-186-236-196; 011-952-301-392-560; 013-263-985-065-905; 013-507-404-965-47X; 013-923-582-078-155; 014-387-553-223-034; 014-478-230-500-897; 016-071-608-061-987; 018-852-362-721-90X; 021-888-019-309-056; 025-191-470-577-077; 026-396-157-821-649; 029-060-475-074-386; 029-170-865-971-100; 030-904-852-090-174; 031-359-098-185-782; 032-617-403-000-47X; 032-866-147-661-179; 033-009-172-927-063; 033-665-111-363-01X; 033-826-675-727-194; 035-121-493-185-77X; 037-736-358-533-675; 040-263-654-109-685; 040-480-276-881-723; 042-610-553-303-952; 044-132-894-728-974; 044-159-705-309-237; 046-194-094-514-122; 046-992-864-415-70X; 047-227-840-923-003; 049-233-483-833-125; 051-200-214-848-194; 055-229-743-989-421; 059-324-737-270-649; 060-571-401-948-931; 061-103-603-617-590; 061-441-591-037-522; 062-425-426-243-433; 064-120-241-480-139; 064-882-080-885-629; 066-775-742-824-171; 067-509-080-881-840; 069-598-426-862-103; 070-182-714-660-465; 071-043-794-851-646; 071-860-511-080-598; 073-062-449-385-011; 075-388-173-703-498; 076-127-382-833-679; 077-432-820-329-956; 077-953-645-699-995; 078-502-451-413-251; 079-756-252-280-528; 081-425-064-777-129; 082-771-848-685-167; 083-502-357-807-490; 087-515-409-353-338; 088-760-502-993-060; 088-816-639-251-033; 089-521-682-198-694; 095-812-608-730-854; 095-864-231-707-084; 096-128-318-948-033; 098-650-338-826-900; 098-915-822-026-711; 104-930-617-788-216; 104-978-804-886-594; 105-801-344-584-829; 106-203-733-818-672; 107-639-872-981-043; 107-787-656-242-291; 109-380-501-047-828; 112-763-015-334-166; 112-880-786-782-058; 118-978-065-165-731; 121-541-135-955-066; 122-019-922-458-426; 129-844-364-602-482; 130-852-150-658-494; 133-206-740-316-331; 135-279-765-882-700; 136-337-152-899-090; 139-105-448-880-74X; 139-470-913-308-008; 140-351-983-960-708; 140-472-625-280-797; 140-568-103-899-660; 140-847-317-688-908; 141-047-267-478-101; 148-206-329-133-492; 150-155-334-117-328; 154-551-939-710-167; 154-943-037-562-241; 155-459-948-277-435; 158-058-849-261-966; 161-106-456-550-953; 162-134-233-068-216; 168-032-700-136-443; 169-958-479-633-760; 175-553-633-906-125; 183-655-285-023-939; 185-552-853-397-834; 186-302-686-916-215; 193-932-907-079-001,0,false,, -197-243-856-016-642,Participatory Design and Democracy: A systematic review,,2023,conference proceedings article,Blucher Design Proceedings,23186968,Editora Blucher,,Lara Liz Freire; Virgínia Tiradentes Souto; Tiago Barros Pontes e Silva; Nayara Moreno de Siqueira,"Recently, the role of Design in relation to Democracy has been discussed in literature, and Participatory Design has proven to be a very adherent term to this relationship. The aim of this work is to discuss Participatory Design as an instrument for the elaboration of transformative remedies, contributing to the maximization of rationality and effectiveness in the design of public policies. For this, the Meta-Analytic Focus Theory was used to analyse the most relevant elements, such as publications, authors, and keywords from literature. The data collection included articles published between 2012 and 2022 and the Bibliometrix and Tagcloud software were used for the investigation. The findings identified that Computer Science and Social Sciences stand out and are the most representative areas, politics, computation, community, innovation, and governance are the most relevant topics related to the subject, and decolonial agenda and contemporary feminist utopia have an important correlation also.",,,294,307,Transformative learning; Participatory design; Rationality; Sociology; Democracy; Management science; Subject (documents); Politics; Corporate governance; Engineering ethics; Participatory evaluation; Relation (database); Social science; Computer science; Public relations; Epistemology; Knowledge management; Political science; Engineering; Management; Library science; Mechanical engineering; Parallels; Pedagogy; Philosophy; Law; Economics; Database,,,,,https://pdf.blucher.com.br/designproceedings/ead2023/2SAO-01Full-03Lara Liz Freire et al.pdf https://doi.org/10.5151/ead2023-2sao-01full-03lara-liz-freire-et-al,http://dx.doi.org/10.5151/ead2023-2sao-01full-03lara-liz-freire-et-al,,10.5151/ead2023-2sao-01full-03lara-liz-freire-et-al,,,0,003-158-928-685-596; 004-824-904-883-780; 005-094-212-121-691; 008-508-918-779-360; 014-101-947-933-091; 037-752-697-110-431; 038-317-334-957-887; 039-297-317-536-408; 041-187-394-821-020; 048-325-988-383-037; 050-847-615-504-633; 055-499-047-519-83X; 062-574-619-054-750; 069-819-212-470-071; 093-936-591-742-526; 116-618-056-161-489; 143-119-038-216-67X,0,true,cc-by,hybrid -197-251-696-058-623,Research Mapping on Takaful Performance,2023-03-01,2023,journal article,Tamkin Journal,29858909,Sharia Economic Applied Research and Training (SMART) Insight,,Irni Nuraini,"This study aims to examine research patterns concerning Takaful Performance. The studied data came from the Scopus database, which was accessed on March 6, 2023. A total of 62 papers were retrieved. The data were analyzed with the Rstudio Bibliometrix program and biblioshiny tools to determine the research advancements on the Takaful Performance. The data demonstrates that the development of Takaful Performance research began in 2009 and has accelerated since 2015. Nazri and Omar are the most productive writer on this subject. Takaful, Malaysia, and Efficiency are the most commonly occurring keywords. According to the themes in the Takaful Performance study that has the potential to be expanded, this research has a great deal of room for growth.",2,1,,,Scopus; Subject (documents); Computer science; Data science; World Wide Web; Political science; MEDLINE; Law,,,,,https://journals.smartinsight.id/index.php/TJ/article/download/162/153 https://doi.org/10.58968/tj.v2i1.162,http://dx.doi.org/10.58968/tj.v2i1.162,,10.58968/tj.v2i1.162,,,0,,1,true,,bronze -197-272-406-415-075,Progress in ubiquitination and hepatocellular carcinoma: a bibliometric analysis.,2025-03-21,2025,journal article,Discover oncology,27306011,Springer Science and Business Media LLC,United States,Ming Li; Zhiliang Xu; Siqin Liang; Qiaoli Lv; Xiaoxiang You; Tinghao Yuan; Jun He; Qiang Tu,"Ubiquitination modifications can affect hepatocellular carcinoma (HCC) progression through various signaling pathways. However, no significant results have been observed regarding protein ubiquitination in HCC's therapeutic transformation. This study aimed to explore the research areas related to ubiquitination and HCC from a bibliometric perspective.; Articles and reviews on HCC and ubiquitination published between 2000 and 2023 were obtained from the Web of Science Core Collection (WOSCC). CiteSpace, VOSviewer, and R-bibliometrix were used for the bibliometric and visualization analyses.; Altogether, 358 papers on ubiquitination and HCC were extracted from the WOSCC. Over 24 years, the number of publications has increased. Since the beginning of 2019, studies related to this topic have increased significantly, indicating that the role of ubiquitination modification in HCC is currently popular. China is the leading country in this field with the largest number of publications. The Chinese Academy of Sciences is one of the most influential institutions. Qiao, Yongxia, and Zhang Jie are highly productive authors with major achievements. The journal Cell Death & Disease had the highest number of publications, and the most highly cited journal was Oncogene. The highest citation burst intensity was Sung (2021). In the keyword strategy map, ""cancer antigens"" are popular keywords in HCC and ubiquitination research.; A comprehensive visual analysis of ubiquitination and HCC research was conducted using bibliometric methods, showing the publications and popular topics in this field over the past two decades, thus providing references for the future direction of ubiquitination and HCC research.; © 2025. The Author(s).",16,1,371,,Hepatocellular carcinoma; Ubiquitin; Cancer research; Oncology; Medicine; Biology; Genetics; Gene,Bibliometric analysis; CiteSpace; Hepatocellular carcinoma; Ubiquitination; VOSviewer,,,Provincial Natural Science Foundation of Jiangxi (20224BAB206061); Provincial Natural Science Foundation of Jiangxi (20224BAB206118); Open Fund for Scientific Research of Jiangxi Cancer Hospital (2021J12); Open Fund for Scientific Research of Jiangxi Cancer Hospital (KFJJ2023YB14); Open Fund for Scientific Research of Jiangxi Cancer Hospital (KFJJ2023YB20); Open Fund for Scientific Research of Jiangxi Cancer Hospital (2021K05); National Natural Science Foundation of China (82260467),,http://dx.doi.org/10.1007/s12672-025-02155-5,40117016,10.1007/s12672-025-02155-5,,PMC11928703,0,001-090-860-890-006; 004-826-653-065-220; 004-951-727-816-326; 010-606-974-669-394; 014-394-621-709-227; 016-748-004-506-131; 018-357-573-508-166; 024-685-595-432-908; 026-395-112-558-483; 030-291-021-915-463; 030-913-235-080-67X; 032-653-436-454-548; 035-777-616-564-107; 048-212-568-253-673; 059-588-547-634-316; 069-146-750-757-148; 069-188-848-590-441; 070-174-569-303-962; 070-709-011-483-560; 073-295-756-384-913; 076-767-833-329-46X; 078-161-343-178-474; 079-050-236-131-309; 083-554-185-926-120; 086-366-735-856-819; 090-309-155-818-211; 092-062-550-269-321; 098-098-046-169-113; 098-389-214-683-235; 101-742-480-952-240; 106-886-997-244-954; 142-647-830-332-642; 149-938-716-584-955; 156-798-395-422-585; 169-751-970-670-758; 171-610-941-737-012,0,true,cc-by,gold -197-317-303-032-203,MAPEAMENTO DA CIÊNCIA COM O PACOTE R BIBLIOMETRIX: UMA APLICAÇÃO NO ESTUDO DE EMPREENDEDORISMO ACADÊMICO,2018-10-09,2018,,,,,,Marco Antonio Domingues; Ilka Maria Escaliante Bianchini; Luiz Alberto Cardoso dos Santos; Suzana Leitão Russo; Sadraque Eneas de Figueiredo Lucena; Daniel Pereira da Silva,"Resumo – O desenvolvimento de novas empresas a partir das descobertas cientificas tem ocupado um papel significativo na area de empreendedorismo e inovacao. O objetivo deste estudo foi mapear a producao cientifica na area de empreendedorismo, particularmente o empreendedorismo academico, analisar os principais autores, fontes de publicacao e artigos mais citados sobre o empreendedorismo academico. Para isso, realizou-se uma pesquisa bibliometrica, usando a ferramenta bibliometrix na base de periodicos SCOPUS. Este artigo apresenta o mapeamento da ciencia na base de dados SCOPUS no periodo entre 1972 e julho de 2018, as dificuldades e problemas encontrados quando se pretende identificar os autores mais produtivos, seus artigos mais citados e toda a analise estatistica propria da bibliometria. Especificamente foram selecionados 370 artigos publicados em periodicos revisados por pares, onde foram identificados 687 autores na bibliometria do bibliometrix utilizando o RStudio. Apresenta como resultado as principais palavras chaves associadas ao tema, os 10 artigos e os 10 autores mais citados, a area geografica e instituicoes a qual eles pertencem, as principais fontes de publicacao, possibilitando o mapeamento da ciencia e facilitando, desta forma, a selecao do material para montagem de um referencial teorico comparando linhas de pensamento, evolucao da discussao do assunto, e posicoes cientifica dentro da area de estudo.",,,,,,,,,,http://www.api.org.br/conferences/index.php/ISTI2018/ISTI2018/paper/view/612,http://www.api.org.br/conferences/index.php/ISTI2018/ISTI2018/paper/view/612,,,3150103091,,0,,0,false,, -197-353-611-450-86X,A Holistic Analysis on Risks of Post-Disaster Reconstruction Using RStudio Bibliometrix,2024-10-31,2024,journal article,Sustainability,20711050,MDPI AG,Switzerland,Merve Serter; Gulden Gumusburun Ayalp,"Post-disaster reconstruction (PDR) is a complex and unpredictable process, especially concerning the construction sector, where understanding associated risks is increasingly vital. This study investigates and evaluates the present condition of post-disaster reconstruction risk (RoPDR) and discerns research trends and deficiencies in the domain via a systematic literature review (SLR) and bibliometric analysis. The Web of Science (WoS) was preferred for its extensive repository of pivotal research publications and its integrated analytical capabilities for producing representative data. This study performed a comprehensive bibliometric analysis of 204 peer-reviewed journal articles regarding the risks associated with post-disaster reconstruction from 1993 to 2024, utilizing the R statistical programming package RStudio Bibliometrix R version 4.3.1 to map the research landscape, identify literature gaps, and analyze rising trends. As a result of the analyses, the risks of post-disaster reconstruction were classified into four main clusters. Despite numerous studies exploring post-disaster reconstruction through diverse perspectives and methodologies, the associated risks of these projects remain inadequately analyzed. This inaugural bibliometric study in the realm of RoPDR utilizes novel techniques, such as the h-index, thematic mapping, and trend topic analysis, to attain a comprehensive understanding. Hence, the outcome of this study will aid scholars and practitioners in thoroughly comprehending the present condition and identifying prospective research directions.",16,21,9463,9463,Risk analysis (engineering); Computer science; Business,,,,,,http://dx.doi.org/10.3390/su16219463,,10.3390/su16219463,,,0,000-632-377-268-396; 001-334-787-669-070; 001-526-847-963-586; 005-026-457-812-592; 005-120-336-857-912; 006-935-562-480-619; 011-516-433-517-969; 012-970-314-086-162; 013-507-404-965-47X; 013-524-854-219-241; 014-386-219-218-809; 014-913-211-523-261; 015-587-877-066-533; 016-293-547-479-557; 017-234-354-033-360; 021-074-386-615-95X; 021-498-839-383-047; 023-990-448-026-20X; 026-026-026-615-273; 026-863-854-708-270; 028-835-666-162-527; 032-830-466-375-423; 032-952-059-031-012; 033-094-178-292-07X; 034-364-911-265-458; 035-568-527-050-541; 035-839-710-947-746; 036-260-910-178-21X; 038-059-206-212-814; 039-185-819-557-384; 040-473-104-394-931; 040-666-958-215-985; 042-943-431-309-753; 043-247-540-121-765; 048-936-622-752-216; 050-057-504-343-666; 050-582-156-742-657; 052-123-121-611-243; 052-408-025-991-548; 052-930-753-851-609; 055-244-476-313-309; 057-597-175-869-158; 057-692-758-172-913; 057-770-664-658-753; 058-409-146-336-382; 058-527-109-865-522; 059-846-180-942-337; 060-434-664-446-270; 060-864-448-983-821; 061-775-772-625-171; 062-204-859-235-675; 066-445-839-070-001; 069-717-990-927-157; 074-785-467-176-454; 074-812-644-318-435; 078-141-013-411-140; 080-743-668-058-245; 081-547-256-855-879; 083-035-818-424-573; 086-501-763-493-153; 088-401-016-994-581; 089-213-152-149-372; 090-925-202-053-813; 091-246-137-769-437; 091-848-577-995-962; 093-859-643-385-676; 097-823-805-869-229; 099-300-590-676-023; 099-499-779-652-472; 100-620-260-328-305; 100-930-418-402-530; 102-694-788-795-301; 104-614-503-574-207; 105-189-832-254-599; 106-532-166-021-110; 107-452-637-425-59X; 108-033-960-943-565; 108-261-620-180-711; 108-968-483-284-045; 109-983-274-110-585; 114-166-633-005-850; 114-875-225-290-682; 115-006-917-489-926; 115-031-623-768-692; 117-613-888-111-840; 121-652-742-486-910; 123-836-435-730-353; 132-146-709-208-131; 138-452-504-415-384; 140-301-258-010-317; 149-687-284-447-581; 156-571-450-751-634; 156-891-942-060-71X; 159-681-349-256-109; 164-196-641-196-061; 166-779-429-290-963; 169-910-183-980-189; 183-237-004-949-320; 183-542-131-655-385; 187-219-410-553-037; 195-992-599-766-658,2,true,,gold -198-140-985-573-968,Research status of the periodic table: a bibliometric analysis,2024-05-29,2024,journal article,Foundations of Chemistry,13864238; 15728463,Springer Science and Business Media LLC,United States,Kamna Sharma; Deepak Kumar Das; Saibal Ray,,26,2,301,314,Periodic table; Astrochemistry; Table (database); Context (archaeology); Field (mathematics); Stars; Chemistry; Theoretical physics; Physics; Epistemology; Earth science; Astrophysics; Computer science; Mathematics; Geology; Paleontology; Philosophy; Quantum mechanics; Data mining; Interstellar medium; Galaxy; Pure mathematics,,,,,,http://dx.doi.org/10.1007/s10698-024-09509-x,,10.1007/s10698-024-09509-x,,,0,004-575-554-121-051; 005-399-136-051-616; 006-525-320-123-502; 011-087-453-725-447; 013-274-668-979-504; 016-247-713-725-294; 016-387-240-056-477; 019-021-349-959-998; 019-686-842-230-152; 019-937-592-993-555; 023-672-601-475-500; 025-164-826-639-432; 025-917-724-863-373; 034-421-851-592-657; 034-453-710-832-350; 034-992-726-371-408; 035-263-054-412-84X; 040-903-201-933-260; 048-254-224-464-034; 050-335-547-133-834; 050-451-339-436-214; 051-621-922-088-873; 055-385-320-804-709; 058-070-360-894-73X; 059-494-509-503-844; 061-124-972-268-384; 069-067-692-550-10X; 070-708-457-505-15X; 072-670-406-800-804; 074-992-211-188-664; 075-744-590-609-126; 079-683-025-227-220; 099-397-104-599-792; 099-507-606-436-920; 101-752-490-869-458; 106-901-062-380-419; 108-280-920-611-388; 108-555-873-059-550; 119-513-499-795-577; 184-644-475-027-490; 192-135-671-580-685; 194-213-345-253-498,0,false,, -198-242-285-769-123,A systematic review on social currency: a one-decade perspective,2023-04-19,2023,journal article,Journal of Financial Services Marketing,13630539; 14791846,Springer Science and Business Media LLC,United Kingdom,Bruno Nogueira Silva; Wesley Vieira da Silva; Alvaro Fabiano Pereira de Macêdo; Natallya de Almeida Levino; Luciano Luiz Dalazen; Fabíola Kaczam; Claudimar Pereira da Veiga,"In consumer finance, certain experiences are recognized in international markets in the use of complementary and social currencies, due to their effects on social inclusion and the reduction of capital accumulation in a globalized economy. In this context, the article aims to review ten years of scientific production of social currency in the Scopus and Web of Science databases. In order to achieve the proposed objective, a systematic literature review was carried out, covering three stages: (1) planning the review, (2) conducting the review and (3) presentation of the final report. As a result of the content analysis of the textual corpus ( n = 67), we now have an up-to-date overview of the literature, through (1) descriptive analysis, (2) bibliographic coupling analysis and (3) word analysis. In addition, as a main contribution, the following were identified: (1) a typology, formed by three classes, which capture contexts of the use of social currency; (2) a methodological framework; and (3) suggestions for the development of future research. In general, the results show that social currency can serve as a complementary currency to the solidarity economy, since the potential of this currency is not disconnected from objectives and normative standards. It is also known that social currency lends itself to emergency use, as it helps to minimize the anxieties of the excluded. However, for many markets, social currency remains a topic far removed from the reality of the underprivileged population. The findings also show the advances made in research focused on social currency, especially considering the contexts in which it is used.",29,2,636,652,Currency; Population; Economics; Business; Sociology; Monetary economics; Demography,,,,,https://link.springer.com/content/pdf/10.1057/s41264-023-00231-x.pdf https://doi.org/10.1057/s41264-023-00231-x,http://dx.doi.org/10.1057/s41264-023-00231-x,,10.1057/s41264-023-00231-x,,,0,000-087-859-141-522; 003-474-131-286-701; 004-507-709-373-436; 005-376-928-880-293; 006-445-594-270-307; 010-805-549-558-118; 011-010-458-917-143; 011-211-158-839-957; 011-824-847-317-769; 014-188-949-581-75X; 019-779-170-204-228; 022-025-951-508-619; 023-927-221-065-800; 024-174-894-985-049; 026-218-722-522-309; 026-757-996-209-398; 027-941-050-568-812; 028-728-563-956-910; 031-500-897-542-627; 032-333-166-909-780; 036-331-444-157-467; 037-513-218-556-578; 038-378-648-749-342; 042-969-359-918-305; 045-524-915-216-417; 046-992-864-415-70X; 048-186-482-458-428; 049-349-365-127-646; 052-050-736-531-181; 053-598-695-896-482; 057-803-697-074-453; 059-855-582-499-379; 062-044-294-047-350; 062-646-603-047-855; 066-117-803-018-954; 069-175-402-924-90X; 070-106-981-184-112; 071-319-111-131-936; 072-610-779-757-007; 072-642-397-195-48X; 073-078-040-299-907; 073-714-936-868-134; 076-306-688-862-601; 076-483-915-807-029; 083-311-225-108-952; 085-300-287-100-525; 085-608-870-590-569; 085-991-825-028-993; 087-140-434-172-629; 090-681-406-980-039; 098-593-199-115-747; 098-925-168-945-324; 100-445-029-445-191; 101-148-446-332-994; 103-805-829-390-120; 109-698-481-199-516; 110-218-636-104-199; 118-269-687-473-307; 122-427-503-724-85X; 127-273-273-384-230; 130-198-386-135-821; 130-459-228-070-690; 138-270-687-058-342; 140-750-078-302-199; 141-200-607-894-303; 151-766-923-245-095; 152-859-244-404-380; 163-382-526-443-63X; 167-657-344-239-625; 179-452-851-634-757,6,true,,bronze -198-324-130-159-08X,A multimethod synthesis of Covid-19 education research: the tightrope between covidization and meaningfulness.,2023-03-21,2023,journal article,Universal access in the information society,16155297; 16155289,Springer Science and Business Media LLC,Germany,Mohammed Saqr; Miroslava Raspopovic Milic; Katina Pancheva; Jovana Jovic; Elitsa V Peltekova; Miguel Á Conde,"This study offers a comprehensive analysis of COVID-19 research in education. A multi-methods approach was used to capture the full breadth of educational research. As such, a bibliometric analysis, structural topic modeling, and qualitative synthesis of top papers were combined. A total of 4,201 articles were retrieved from Scopus, mostly published from 2019 to 2021. In this work special attention is paid to analyzing and synthesizing findings about: (i) status of research about COVID-19 regarding frequencies, venues, publishing countries, (ii) identification of main topics in the COVID-19 research, and (iii) identification of the major themes in most cited articles and their impact on the educational community. Structural topic modeling identified three main groups of topics that related to education in general, moving to online education, or diverse topics (e.g., perceptions, inclusion, medical education, engagement and motivation, well-being, and equality). A deeper analysis of the papers that received most attention revealed that problem understanding was the dominating theme of papers, followed by challenges, impact, guidance, online migration, and tools and resources. A vast number of papers were produced. However, thoughtful, well-planned, and meaningful research was hard to conceptualize or implement, and a sense of urgency led to a deluge of research with thin contributions in a time of dire need to genuine insights.",23,3,1,1176,Scopus; Identification (biology); Inclusion (mineral); Coronavirus disease 2019 (COVID-19); Theme (computing); Higher education; Psychology; Computer science; Sociology; Social science; World Wide Web; MEDLINE; Political science; Medicine; Botany; Disease; Pathology; Infectious disease (medical specialty); Law; Biology,,,,EUROPEAN UNINON; Academy of Finland; University of Eastern Finland (UEF) including Kuopio University Hospital,https://link.springer.com/content/pdf/10.1007/s10209-023-00989-w.pdf https://doi.org/10.1007/s10209-023-00989-w,http://dx.doi.org/10.1007/s10209-023-00989-w,37361671,10.1007/s10209-023-00989-w,,PMC10027595,0,000-615-687-279-766; 002-799-061-909-801; 004-505-818-144-65X; 005-641-047-839-340; 006-026-953-771-298; 008-274-139-069-264; 009-123-140-186-933; 010-422-471-993-735; 010-984-072-645-017; 011-515-215-626-636; 013-261-296-086-031; 013-507-404-965-47X; 014-324-438-434-778; 015-282-757-406-022; 016-653-244-253-995; 019-042-700-105-600; 019-525-636-498-126; 019-693-491-998-092; 020-164-468-760-926; 020-187-364-592-309; 023-489-512-471-748; 023-705-701-259-088; 024-456-309-874-467; 026-501-432-015-935; 027-228-325-789-785; 028-055-288-631-535; 029-374-180-279-343; 033-134-448-543-179; 034-394-759-418-25X; 035-536-694-866-330; 036-707-766-001-812; 042-873-006-093-110; 043-607-433-970-311; 046-294-504-718-880; 047-271-913-022-424; 047-985-475-521-42X; 048-689-378-476-831; 049-768-496-129-664; 051-161-989-385-165; 054-343-350-778-175; 057-547-458-720-921; 058-368-634-163-996; 060-529-707-652-552; 061-746-598-406-033; 062-966-274-867-790; 063-016-317-312-750; 063-278-690-277-172; 065-785-840-382-402; 067-505-607-492-596; 068-992-303-641-342; 069-495-841-375-087; 070-190-701-485-020; 071-382-363-354-142; 072-606-459-592-758; 073-211-333-314-111; 073-610-054-203-935; 074-689-637-760-304; 075-078-699-004-241; 083-911-142-717-92X; 084-926-011-346-063; 085-014-716-553-980; 086-415-686-065-591; 087-132-171-970-740; 087-383-770-722-091; 088-960-462-438-498; 093-591-384-125-348; 095-256-350-312-529; 101-659-813-442-306; 102-282-464-200-171; 103-952-266-984-960; 104-459-093-336-857; 105-722-848-909-054; 105-929-436-002-892; 107-369-695-103-970; 111-719-910-096-809; 119-018-907-192-25X; 124-906-890-008-714; 129-137-947-962-065; 131-930-115-630-143; 132-459-055-750-091; 137-728-365-772-899; 139-483-982-817-968; 148-567-648-473-21X; 151-122-527-546-976; 151-521-298-638-401; 156-492-625-724-342; 168-582-450-317-992; 181-722-377-549-000; 186-794-376-687-510; 188-607-527-971-68X,5,true,cc-by,hybrid -198-674-284-967-40X,Bibliometric analysis and systematic review on the electrokinetic remediation of contaminated soil and sediment.,2024-12-12,2024,journal article,Environmental geochemistry and health,15732983; 02694042,Springer Science and Business Media LLC,Netherlands,Zhonghong Li; Xiaoguang Li,,47,1,15,,Environmental remediation; Electrokinetic remediation; Environmental science; Sediment; Soil contamination; Pollutant; Environmental engineering; Soil Pollutants; Environmental engineering science; Contamination; Environmental chemistry; Soil water; Soil science; Biogeosciences; Earth science; Geology; Chemistry; Biology; Ecology; Paleontology; Organic chemistry,Bibliometric analysis; Electrokinetic remediation; Heavy metals; Organic pollutant; Research hotspot,Bibliometrics; Environmental Restoration and Remediation/methods; Soil Pollutants/analysis; Geologic Sediments/chemistry,Soil Pollutants,the National Key R&D Program of China (No.2023YFE0113103),,http://dx.doi.org/10.1007/s10653-024-02330-7,39666177,10.1007/s10653-024-02330-7,,,0,000-321-036-605-982; 000-937-580-735-989; 001-526-847-963-586; 002-052-422-936-00X; 002-130-882-589-855; 004-008-585-407-289; 004-639-675-182-475; 005-921-945-449-113; 006-635-770-736-426; 007-797-705-296-151; 008-498-934-844-226; 010-071-304-836-036; 010-138-127-907-262; 010-208-269-917-811; 012-524-513-819-859; 013-100-130-697-548; 013-466-800-017-924; 013-507-404-965-47X; 015-034-924-123-802; 015-192-268-650-412; 015-564-316-776-509; 015-867-552-686-204; 017-392-341-127-951; 017-455-993-222-482; 017-538-367-198-95X; 021-135-602-837-781; 021-862-558-053-365; 022-254-363-759-39X; 022-325-727-621-777; 022-406-340-840-582; 022-837-344-337-655; 023-195-929-609-841; 025-415-604-724-598; 030-636-187-060-312; 030-897-900-343-664; 031-476-729-245-677; 033-259-881-691-577; 034-393-835-375-892; 034-405-274-043-841; 036-527-684-864-405; 037-850-246-636-249; 038-161-895-845-123; 041-752-589-805-265; 044-015-610-610-93X; 045-011-672-732-420; 049-703-101-890-145; 051-860-274-384-321; 052-457-524-814-299; 055-585-583-652-950; 056-193-163-479-788; 060-036-012-123-894; 062-619-677-040-652; 064-400-499-357-900; 065-366-125-039-908; 068-267-348-767-625; 068-424-627-896-004; 070-726-360-364-214; 072-030-652-269-056; 074-938-989-695-424; 076-789-562-599-659; 081-150-424-178-93X; 082-013-343-605-384; 085-640-008-443-885; 090-291-610-985-44X; 092-064-128-796-299; 102-905-616-101-155; 103-040-052-680-783; 104-492-836-377-794; 105-844-772-985-16X; 105-971-537-658-179; 107-081-998-429-967; 110-649-954-532-900; 116-873-782-444-414; 118-447-331-352-589; 121-556-685-448-044; 122-894-452-386-290; 123-402-071-166-887; 123-863-346-329-764; 129-820-586-478-337; 146-084-673-090-318; 149-592-935-156-680; 155-175-199-154-571; 155-803-067-417-039; 156-380-764-717-920; 166-741-799-974-357; 167-100-185-163-011; 168-685-104-046-220; 189-098-072-871-773; 190-219-095-085-576; 191-850-207-364-133,2,false,, -198-853-050-676-582,A Systematic Review Of Literature Of Students With Physical Disability: A Bibliometric Analysis Using Bibliometrix And Vosviewer,2024-09-06,2024,journal article,African Journal of Biomedical Research,11195096,Green Publication,Nigeria,Rashida Salmani,,,,177,193,Psychology,,,,,,http://dx.doi.org/10.53555/ajbr.v27i1s.1427,,10.53555/ajbr.v27i1s.1427,,,0,,0,false,, -198-886-854-639-438,Artificial intelligence in otorhinolaryngology: current trends and application areas.,2025-02-17,2025,journal article,European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,14344726; 09374477,Springer Science and Business Media LLC,Germany,Emre Demir; Burak Numan Uğurlu; Gülay Aktar Uğurlu; Gülçin Aydoğdu,"This study aims to perform a bibliometric analysis of scientific research on the use of artificial intelligence (AI) in the field of Otorhinolaryngology (ORL), with a specific focus on identifying emerging AI trend topics within this discipline.; A total of 498 articles on AI in ORL, published between 1982 and 2024, were retrieved from the Web of Science database. Various bibliometric techniques, including trend keyword analysis and factor analysis, were applied to analyze the data.; The most prolific journal was the European Archives of Oto-Rhino-Laryngology (n = 67). The USA (n = 200) and China (n = 61) were the most productive countries in AI-related ORL research. The most productive institutions were Harvard University / Harvard Medical School (n = 71). The leading authors in this field were Lechien JR. (n = 18) and Rameau A. (n = 17). The most frequently used keywords in the AI research were cochlear implant, head and neck cancer, magnetic resonance imaging (MRI), hearing loss, patient education, diagnosis, radiomics, surgery, hearing aids, laryngology ve otitis media. Recent trends in otorhinolaryngology research reflect a dynamic focus, progressing from hearing-related technologies such as hearing aids and cochlear implants in earlier years, to diagnostic innovations like audiometry, psychoacoustics, and narrow band imaging. The emphasis has recently shifted toward advanced applications of MRI, radiomics, and computed tomography (CT) for conditions such as head and neck cancer, chronic rhinosinusitis, laryngology, and otitis media. Additionally, increasing attention has been given to patient education, quality of life, and prognosis, underscoring a holistic approach to diagnosis, surgery, and treatment in otorhinolaryngology.; AI has significantly impacted the field of ORL, especially in diagnostic imaging and therapeutic planning. With advancements in MRI and CT-based technologies, AI has proven to enhance disease detection and management. The future of AI in ORL suggests a promising path toward improving clinical decision-making, patient care, and healthcare efficiency.; © 2025. The Author(s).",282,5,2697,2707,Otorhinolaryngology; Medicine; Laryngology; Audiology; Medical physics; General surgery; Surgery,AI; Artificial intelligence; Bibliometric analysis; Deep learning; Otorhinolaryngology; Research trends,Otolaryngology/trends; Humans; Artificial Intelligence/trends; Bibliometrics; Otorhinolaryngologic Diseases/diagnosis,,Hitit University,,http://dx.doi.org/10.1007/s00405-025-09272-5,40019544,10.1007/s00405-025-09272-5,,PMC12055906,0,000-096-795-149-545; 003-180-702-893-000; 005-526-867-024-063; 007-227-214-529-905; 007-682-609-364-310; 008-001-381-164-047; 008-183-300-126-98X; 013-507-404-965-47X; 018-494-338-027-857; 020-562-289-070-325; 022-687-598-505-865; 031-157-524-649-143; 032-966-615-727-81X; 035-533-619-166-656; 040-337-849-918-14X; 045-139-485-435-300; 045-608-318-399-874; 045-809-439-877-095; 047-915-648-675-109; 047-936-776-104-928; 058-430-800-761-671; 062-219-917-484-912; 062-333-200-357-069; 062-709-868-793-162; 062-965-720-323-327; 064-092-869-721-81X; 065-026-117-646-926; 070-171-076-842-622; 076-073-258-943-079; 078-841-886-627-861; 079-686-634-144-344; 082-499-961-451-303; 084-085-446-971-075; 084-694-211-461-402; 086-145-581-055-920; 093-432-986-683-920; 097-492-409-393-579; 098-248-118-236-954; 099-846-510-418-708; 107-345-140-955-559; 110-258-639-229-786; 113-975-649-279-139; 117-770-946-943-485; 122-045-927-576-973; 123-188-836-704-225; 125-331-735-099-806; 137-594-152-990-795; 139-008-392-629-710; 144-464-017-240-260; 144-805-675-016-255; 146-419-393-196-62X; 155-113-098-531-91X; 162-600-970-928-074; 171-885-998-770-73X; 178-581-375-962-104; 178-727-996-059-961; 179-187-015-487-996; 182-630-449-310-997; 185-068-034-629-588; 196-885-106-392-719,3,true,cc-by,hybrid -199-286-673-720-728,Components influencing parasitism by Dadaytrema oxycephala (Digenea: Cladorchiidae) in Neotropical fish.,2023-03-17,2023,journal article,Parasitology research,14321955; 09320113,Springer Science and Business Media LLC,Germany,Lidiany Doreto Cavalcanti; Élida Jerônimo Gouveia; Gabriela Michelan; Atsler Luana Lehun; João Otávio Santos Silva; Wagner Toshio Hasuike; Márcia Regina Russo; Ricardo Massato Takemoto,,122,5,1221,1228,Biology; Ecology; Generalist and specialist species; Abundance (ecology); Parasitism; Range (aeronautics); Context (archaeology); Trophic level; Digenea; Host (biology); Nestedness; Zoology; Species richness; Habitat; Helminths; Trematoda; Paleontology; Materials science; Composite material,Digenea; Host-parasite relationship; Parasite ecology,Animals; Fishes/parasitology; Trematoda; Parasites; Phylogeny; Water; Host-Parasite Interactions; Fish Diseases/parasitology,Water,,,http://dx.doi.org/10.1007/s00436-023-07822-6,36930288,10.1007/s00436-023-07822-6,,,0,000-802-317-916-450; 002-841-581-308-782; 004-649-354-196-592; 004-990-965-810-28X; 005-356-926-965-156; 005-578-659-032-282; 006-154-323-432-140; 007-576-606-206-684; 008-456-476-303-987; 009-929-247-574-509; 012-769-660-651-940; 013-507-404-965-47X; 014-147-234-732-445; 015-012-838-938-08X; 016-448-820-258-477; 017-170-347-892-781; 017-266-581-600-325; 021-206-929-542-016; 022-733-132-907-832; 024-874-248-052-719; 036-414-951-062-327; 039-103-863-055-697; 039-298-943-572-603; 042-535-236-302-73X; 043-377-400-842-574; 043-481-011-879-277; 044-553-188-231-720; 050-333-676-606-715; 056-347-875-216-782; 059-792-551-573-630; 060-166-602-448-66X; 064-336-085-166-094; 064-411-734-233-638; 068-929-765-504-316; 076-883-379-365-96X; 077-582-333-471-107; 080-820-303-405-677; 081-488-711-150-17X; 085-298-400-006-873; 086-596-255-437-248; 088-963-097-096-998; 090-589-891-279-438; 101-116-070-523-832; 117-330-612-663-994; 121-450-997-201-096; 128-630-639-756-991; 138-185-970-197-114; 149-187-610-553-275; 168-743-978-576-233,2,false,, -199-581-292-695-831,Mapping trends and analyzing key themes in low-cost sensors for air quality monitoring,2025-06-03,2025,journal article,Earth Science Informatics,18650473; 18650481,Springer Science and Business Media LLC,Germany,Kemal Maulana Alhasa; Hernani Yulinawati; Deni Kurnia; Heru Dwi Wahyono; Satmoko Yudo; Irwan Kustianto; Dodi Rusjadi Tatang Endi,,18,3,,,,,,,Research Organization for Life Sciences and Environment at the National Research and Innovation Agency,,http://dx.doi.org/10.1007/s12145-025-01927-5,,10.1007/s12145-025-01927-5,,,0,000-262-673-161-870; 000-381-869-224-169; 000-550-709-234-08X; 000-946-940-978-912; 001-611-971-459-99X; 001-666-686-542-928; 002-052-422-936-00X; 002-443-195-725-955; 002-505-196-224-096; 003-485-141-818-015; 003-789-025-804-794; 003-854-235-839-563; 003-904-866-297-257; 004-493-580-140-310; 004-917-911-575-180; 005-699-366-401-110; 006-030-624-587-395; 006-155-030-545-963; 006-655-565-154-871; 007-171-642-973-770; 008-138-822-063-67X; 008-707-215-999-801; 009-290-269-732-93X; 010-442-924-794-711; 010-483-995-287-064; 010-852-511-939-937; 011-398-324-571-291; 011-513-538-716-661; 012-016-431-764-46X; 012-772-607-947-977; 012-906-621-718-303; 013-019-332-476-665; 013-108-961-974-995; 013-349-571-215-560; 013-507-404-965-47X; 014-046-451-131-889; 014-399-376-326-54X; 014-399-790-170-229; 015-206-132-274-782; 016-020-089-856-613; 016-658-390-411-229; 016-897-034-386-889; 017-244-775-163-517; 018-271-044-143-037; 019-448-116-587-620; 019-654-913-057-38X; 021-286-966-992-692; 021-608-038-980-575; 022-289-497-498-877; 023-674-829-642-546; 024-147-013-128-503; 024-484-290-905-611; 024-721-627-466-260; 025-158-548-258-726; 025-521-885-390-676; 025-528-238-574-411; 025-768-555-986-631; 025-904-206-655-512; 027-175-018-388-862; 027-379-825-215-25X; 027-615-789-277-040; 027-635-056-011-016; 028-796-398-139-291; 029-928-735-878-270; 029-932-333-181-296; 030-364-691-709-487; 030-745-546-616-486; 031-633-611-330-987; 032-003-209-247-421; 032-575-044-064-769; 032-662-169-841-846; 033-628-390-114-792; 034-036-048-535-687; 034-304-357-542-424; 034-387-497-958-313; 034-407-525-074-431; 034-629-109-266-008; 035-154-242-161-889; 036-217-832-729-19X; 036-588-490-297-181; 037-003-269-183-724; 038-677-193-259-610; 040-235-350-479-531; 041-607-285-804-756; 042-309-259-471-338; 042-364-246-043-870; 043-558-268-739-803; 044-653-289-032-809; 044-752-992-865-734; 045-191-640-252-001; 045-830-876-527-081; 045-836-997-151-954; 046-130-905-502-203; 046-825-910-623-465; 047-451-671-397-87X; 047-708-458-825-653; 048-478-325-599-889; 049-318-357-997-578; 049-656-156-663-370; 049-739-095-939-946; 052-667-247-586-499; 053-908-003-811-54X; 055-410-222-398-26X; 055-587-202-752-376; 056-632-470-389-442; 057-940-718-150-162; 060-306-837-882-198; 061-759-484-358-97X; 061-840-004-848-872; 062-853-890-675-863; 063-883-331-542-005; 064-238-987-790-989; 064-436-384-272-450; 066-819-591-703-12X; 066-873-089-298-728; 068-225-108-757-529; 068-788-390-347-986; 069-163-261-246-78X; 070-498-265-326-242; 070-791-835-923-368; 072-327-545-385-577; 072-883-400-911-799; 073-766-732-122-300; 074-022-882-746-551; 074-807-018-520-488; 075-044-336-809-985; 077-721-479-779-857; 077-832-327-206-242; 077-913-187-680-093; 078-269-214-994-840; 081-258-086-272-361; 081-607-329-848-39X; 082-092-498-856-848; 086-591-117-293-829; 088-167-909-434-60X; 088-749-124-700-998; 089-751-962-007-630; 090-277-874-730-431; 090-451-966-606-551; 090-741-034-726-962; 091-032-874-276-970; 091-786-288-258-746; 095-616-616-674-110; 098-351-713-669-338; 098-902-121-262-33X; 100-032-679-601-402; 100-071-440-340-724; 101-083-520-524-640; 102-015-801-205-189; 105-651-908-666-694; 106-544-612-412-225; 106-907-202-837-351; 107-172-313-982-182; 108-198-427-178-573; 108-451-608-366-529; 109-000-484-598-291; 110-804-773-324-106; 111-017-691-591-466; 111-806-313-986-112; 113-337-799-811-657; 113-799-617-689-74X; 115-357-742-026-253; 115-562-324-781-523; 116-192-436-885-045; 116-545-813-640-686; 118-029-051-876-044; 118-630-183-097-656; 119-101-290-363-385; 119-896-822-537-81X; 122-827-252-276-011; 123-557-956-182-274; 123-852-660-115-840; 126-244-118-589-472; 127-281-094-195-346; 127-552-417-873-407; 129-973-591-331-169; 131-994-908-003-978; 132-658-576-749-418; 135-224-419-785-280; 137-041-974-927-701; 144-325-977-077-659; 144-633-901-883-499; 145-484-469-316-064; 146-381-551-834-084; 146-474-167-331-880; 148-975-371-581-885; 149-368-705-324-11X; 152-267-083-348-111; 152-450-990-606-335; 152-467-542-789-925; 153-031-495-169-406; 153-906-268-936-723; 155-457-155-778-177; 156-369-986-435-470; 156-562-799-107-062; 158-185-003-536-702; 158-601-922-619-39X; 160-117-072-328-023; 161-098-896-393-122; 164-847-402-288-475; 166-735-136-483-337; 168-173-256-181-983; 174-555-620-659-279; 179-465-271-253-256; 180-523-746-755-152; 181-633-973-216-339; 181-876-631-579-283; 182-348-051-079-271; 183-273-391-540-784; 183-487-661-118-748; 183-786-499-041-569; 185-161-520-969-859; 189-307-745-390-48X; 192-135-671-580-685; 197-011-307-700-908; 197-376-195-459-903; 197-761-550-454-658,0,false,, -199-719-093-249-66X,A Bibliometric Study for Plant RNA Editing Research: Trends and Future Challenges.,2022-12-23,2022,journal article,Molecular biotechnology,15590305; 10736085,Springer Science and Business Media LLC,United States,Huihui Zhang; Yan Zheng; Guoshuai Zhang; Yujing Miao; Chang Liu; Linfang Huang,,65,8,1207,1227,RNA editing; RNA; Biology; Computational biology; Genetics; Gene,Bibliometric; Databases; Plant RNA editing; RNA prediction tools; Research streams; Research trends,"Humans; RNA, Plant/genetics; RNA Editing; RNA, Messenger/metabolism; Mitochondria/genetics; Bibliometrics","RNA, Plant; RNA, Messenger",National Science & Technology Fundamental Resources Investigation Program of China (2018FY100701); the Open Research Fund of Chengdu University of Traditional Chinese Medicine Key Laboratory of Systematic Research of Distinctive Chinese Medicine Resources in Southwest China (003109034001); the National Natural Science Foundation of China (81473315); Beijing Natural Scientific Foundation (7202135),,http://dx.doi.org/10.1007/s12033-022-00641-7,36562872,10.1007/s12033-022-00641-7,,,0,002-052-422-936-00X; 004-114-271-900-563; 004-279-197-266-394; 005-861-756-009-889; 006-755-194-899-783; 007-037-897-657-465; 008-853-445-919-34X; 009-869-288-294-261; 011-003-053-500-483; 012-231-005-959-143; 013-161-529-314-157; 013-507-404-965-47X; 017-058-617-787-923; 020-420-746-878-204; 023-841-019-437-52X; 024-629-084-497-607; 026-241-094-652-238; 027-915-345-179-794; 030-806-787-422-793; 031-895-978-784-715; 032-151-156-348-126; 032-316-066-125-482; 036-656-168-693-890; 038-338-769-597-748; 038-724-529-238-725; 040-696-474-834-541; 041-272-295-929-825; 042-864-566-777-815; 043-624-717-327-891; 044-449-865-125-563; 046-566-739-441-077; 048-413-455-771-379; 049-935-800-556-536; 053-210-861-999-951; 056-227-793-352-012; 063-569-595-929-603; 064-815-190-989-082; 066-730-820-952-111; 068-421-621-230-590; 070-400-963-471-561; 072-450-342-360-373; 073-313-249-616-368; 075-507-429-470-122; 077-813-347-067-151; 078-812-911-452-782; 085-007-740-064-890; 088-062-966-886-070; 088-315-141-251-719; 095-026-329-647-048; 097-735-927-396-191; 098-715-786-816-049; 099-437-509-613-023; 099-684-415-931-459; 101-472-531-956-835; 101-752-490-869-458; 102-318-600-224-71X; 115-856-365-361-668; 121-298-714-314-442; 128-612-588-897-962; 139-197-291-317-668,2,false,, -199-719-981-679-369,Research Trends on Political Participation of School Aged Children and Adolescents: Bibliometric Mapping and Content Analysis,2025-01-10,2025,journal article,Child Indicators Research,1874897x; 18748988,Springer Science and Business Media LLC,Germany,Şehide Kilinc,,18,2,753,787,Content analysis; Politics; Socioeconomic status; Social science; Political science; Sociology; Demography; Population; Law,,,,,,http://dx.doi.org/10.1007/s12187-024-10214-6,,10.1007/s12187-024-10214-6,,,0,000-540-230-926-667; 001-917-271-588-127; 003-123-419-973-434; 003-394-757-610-657; 003-437-021-631-153; 004-644-374-443-412; 004-845-694-770-536; 005-192-645-017-24X; 005-883-538-394-35X; 007-134-905-887-08X; 008-119-506-086-34X; 009-652-434-204-539; 012-642-775-724-638; 012-655-154-397-710; 013-022-208-444-671; 013-507-404-965-47X; 014-470-112-952-423; 014-633-980-451-518; 015-951-251-133-94X; 017-391-640-065-004; 017-609-547-001-128; 017-852-024-512-762; 018-282-137-427-518; 018-509-299-522-634; 018-896-691-473-120; 020-832-485-644-012; 021-241-050-803-442; 021-537-619-107-154; 023-927-221-065-800; 024-127-144-509-711; 024-250-960-764-239; 024-644-458-601-583; 026-016-295-443-909; 026-979-588-489-355; 028-179-585-004-663; 031-294-333-515-450; 033-983-532-447-338; 033-997-136-772-646; 034-706-134-143-997; 034-898-730-773-388; 035-699-269-235-948; 037-048-826-933-364; 037-439-847-273-594; 038-362-813-426-613; 041-018-738-381-675; 041-027-753-633-011; 041-084-324-378-084; 045-422-273-148-899; 046-992-864-415-70X; 049-538-453-030-441; 050-999-594-837-529; 056-591-042-068-185; 057-521-908-382-988; 057-928-447-938-457; 058-941-879-911-314; 059-612-347-233-259; 061-266-413-090-958; 064-284-093-714-378; 065-757-388-969-718; 067-749-003-766-091; 068-866-358-443-303; 069-509-418-458-189; 071-149-112-308-327; 073-538-420-016-993; 075-633-233-350-222; 076-498-170-063-038; 076-670-072-075-774; 077-971-904-700-145; 079-406-762-324-017; 081-089-942-993-053; 083-233-429-885-517; 085-494-573-356-52X; 086-037-976-083-821; 086-251-231-781-489; 091-623-563-412-853; 092-629-201-609-599; 094-115-395-660-046; 096-827-675-019-913; 096-933-114-292-425; 099-291-572-837-813; 101-543-534-848-384; 108-854-209-510-550; 109-268-359-735-899; 111-955-919-742-832; 119-630-426-559-496; 125-797-339-254-573; 130-135-515-780-571; 130-702-775-063-585; 133-109-521-528-364; 134-503-392-309-06X; 135-693-810-018-166; 141-200-607-894-303; 141-289-222-959-472; 146-772-912-074-534; 155-104-634-799-748; 157-190-528-594-622; 166-227-694-983-327; 166-573-417-611-527; 173-906-463-901-708; 180-301-184-224-398,0,false,, -199-838-929-882-150,Global research trends of the studies on Murraya koenigii (L.) spreng: a Scopus-based comprehensive bibliometric investigation (1965–2023),2023-09-14,2023,journal article,Bulletin of the National Research Centre,25228307,Springer Science and Business Media LLC,,Siddig Ibrahim Abdelwahab; Manal Mohamed Elhassan Taha,"Abstract; Background; Murraya koenigii (L.) Spreng. has several well-established nutritional and therapeutic applications. Following our desire to investigate the global and scientific community's knowledge of medicinal plants, this study was intended to examine the evolution of knowledge related to M. Koenigii studies. The primary purpose of this paper is to clarify the status of these studies, investigate their methods, findings, and trends, and define their significance within the current research landscape.; ; Results; To achieve these goals, bibliometric analysis was conducted, retrieving, and analyzing 934 original articles published between 1965 and 2023 based on Scopus Dataset results. Data were exported as CVS (comma-separated values) and BibTex files and analyzed using Bibliometrix and VOSviewer software. Articles from 502 sources have been identified, averaging 21.8 citations per document. The research in this plant has had exponential growth (R2 = 0.77). International co-authorship is 13.08%. India and Malaysia are the top publishing countries. Debajo, A.C. (Nigeria), Phatak,R.S. (India), and Sukari,M.A. (Malaysia) are the most productive authors. The top source is the Journal of Ethnopharmacology. ""Green synthesis,"" ""nanoparticles,"" ""oxidative stress,"" ""Asian citrus psyllid,"" ""apoptosis,"" ""antimicrobial,"" ""anticancer,"" ""Chromatographic profile,"" ""bioactive compounds,"" and ""alkaloids"" are strongly related to the current trends in M. Koenigii research. Regarding the specialized topics, M. Koenigii's study concentrated on using this plant as an antioxidant agent in manufacturing and biological systems. Dynamic subjects like chromatographic profiles, essential oils, and Asian citrus psyllids were included in the motor theme.; ; Conclusions; The current study used bibliometric techniques to evaluate research on M. Koenigii and identify trends and potential future research hot spots.; ",47,1,,,Murraya; Scopus; Bibliometrics; Traditional medicine; Geography; Biology; Computer science; Botany; Library science; Medicine; MEDLINE; Biochemistry,,,,,https://bnrc.springeropen.com/counter/pdf/10.1186/s42269-023-01113-x https://doi.org/10.1186/s42269-023-01113-x,http://dx.doi.org/10.1186/s42269-023-01113-x,,10.1186/s42269-023-01113-x,,,0,006-251-585-515-098; 008-360-979-606-369; 013-607-549-896-899; 015-045-691-756-900; 015-386-881-393-94X; 015-511-033-498-597; 015-796-708-962-485; 017-060-028-866-052; 017-219-368-541-491; 028-447-585-102-130; 028-859-229-196-901; 028-986-738-198-712; 030-943-205-399-409; 031-913-636-872-412; 034-222-466-209-701; 037-902-318-143-016; 040-733-704-950-098; 041-467-670-045-264; 041-896-448-720-359; 042-226-468-938-922; 042-599-431-051-772; 042-661-220-726-359; 045-975-938-785-80X; 046-266-889-121-736; 047-064-297-906-872; 052-209-026-702-494; 061-879-595-331-215; 069-524-993-010-132; 075-237-924-964-00X; 075-956-563-243-741; 089-347-565-042-075; 090-348-763-548-456; 090-405-810-044-065; 094-262-746-001-094; 097-574-229-695-878; 104-110-222-656-645; 107-928-389-594-335; 108-033-960-943-565; 119-064-123-984-248; 140-454-332-410-835; 141-113-027-537-312; 153-213-675-315-201; 164-573-678-211-828; 165-536-236-546-94X; 167-196-786-758-677; 168-883-566-346-09X; 174-811-924-969-305; 179-810-109-499-666,1,true,cc-by,gold -199-932-112-235-996,Main areas of research and scientific production regionalized by Policosanol biorefining route: from the 1990s to the 2020s,2023-07-12,2023,dataset,Zenodo (CERN European Organization for Nuclear Research),,,,Rilton Gonçalo Bonfim Primo; Ricardo de Araújo Kalid; Manuel Díaz de los Ríos,"This Table 1 presents the results of surveys, in 18 Ibero-American countries and in the world, carried out in the Science Citation Index Expanded (SCI-E) or Web of Science - Core Collection - Clarivate Analytics – (WoS) and Scopus (Elsevier): AR - Argentina, BR - Brazil, CL - Chile, CO - Colombia, CR - Cota Rica, CU - Cuba, DO - Dominican Republic, EC - Ecuador, ES - Spain, GT - Guatemala, HN - Honduras, MX - Mexico, NI - Nicaragua, PA - Panama, PE - Peru, PT - Portugal, SV - El Salvador, UY - Uruguay. Data from the two databases were merged using the Bibliometrix of R program (Version 4.1.1), as well as the Biblioshiny, for scientometrics and bibliometrics. Merging the Scopus and Web of Science bases, the scientometric methodology of K-Synth (Bibliometrix) is applied here, according to which the scientific production of each country is measured by the number of appearances of authors by country affiliations. Thus, if in an article there are, for example, three authors working, respectively, in Brazil, Spain and the USA, the appearance counter will be increased by 1 for each of them. Due to the identification of some gaps, the electronically merged data were reconciled with the original databases.",,,,,Biorefining; Production (economics); Business; Regional science; Engineering; Economics; Geography; Waste management; Microeconomics; Biofuel; Biorefinery,,,,,https://zenodo.org/doi/10.5281/zenodo.8140866,http://dx.doi.org/10.5281/zenodo.8140866,,10.5281/zenodo.8140866,,,0,,0,false,, -199-997-902-033-835,Bibliometric analysis of worldwide research on Polycythemia Vera in the 21st century.,2024-04-09,2024,journal article,Annals of hematology,14320584; 09395555,Springer Science and Business Media LLC,Germany,Zhengjiu Cui; Fei Luo; Yuan Zhang; Juanjuan Diao; Yueli Pan,,103,10,3905,3920,Bibliometrics; Ranking (information retrieval); Web of science; Medicine; Citation; Polycythemia vera; Library science; Computer science; Internal medicine; Information retrieval; Meta-analysis,Bibliometric analysis; Cooperation; Polycythemia Vera; Trends; Visual analytics; Web of Science,Humans; Bibliometrics; Biomedical Research/trends; Janus Kinase 2/genetics; Polycythemia Vera/therapy,Janus Kinase 2,,,http://dx.doi.org/10.1007/s00277-024-05723-x,38592500,10.1007/s00277-024-05723-x,,,0,001-751-384-540-659; 002-052-422-936-00X; 005-719-088-540-57X; 007-740-749-168-576; 011-430-718-743-911; 013-507-404-965-47X; 021-766-195-146-182; 024-716-638-608-432; 025-824-143-908-307; 025-976-074-293-080; 026-077-304-931-031; 026-125-097-821-385; 027-024-778-655-144; 033-697-671-851-050; 035-461-694-389-841; 035-706-626-883-648; 041-672-475-484-504; 044-451-359-914-570; 044-552-233-078-039; 046-796-994-188-578; 050-122-364-056-427; 051-905-317-081-07X; 060-309-910-492-094; 068-979-995-628-344; 069-524-957-455-10X; 069-837-312-455-775; 070-912-457-996-209; 071-878-836-294-733; 083-650-915-218-629; 087-537-888-518-685; 090-870-275-844-370; 093-238-535-710-513; 110-670-707-977-319; 111-179-730-883-800; 114-078-429-963-357; 114-530-843-125-584; 119-070-333-133-805; 120-157-265-784-493; 121-820-960-044-715; 137-600-182-767-808; 139-822-823-187-915; 141-770-516-078-794; 142-602-854-866-72X; 150-234-821-510-720; 151-230-586-655-214; 151-855-153-438-687; 158-263-061-677-328; 165-756-000-444-677,1,false,, diff --git a/sources/new/WOS/WoS_collection.txt b/sources/new/WOS/WoS_collection.txt deleted file mode 100644 index 1c5a786ec..000000000 --- a/sources/new/WOS/WoS_collection.txt +++ /dev/null @@ -1,20888 +0,0 @@ -FN Clarivate Analytics Web of Science -VR 1.0 -PT J -AU Aria, M - Cuccurullo, C -AF Aria, Massimo - Cuccurullo, Corrado -TI bibliometrix: An R-tool for comprehensive science mapping - analysis -SO JOURNAL OF INFORMETRICS -LA English -DT Article -DE sBibliometrics; Science mapping; Workflow; Co-citation; Bibliographic - coupling; R package -ID INFORMATION-SCIENCE; SCIENTIFIC WORKFLOWS; AUTHOR COCITATION; CITATION - IMAGE; ALGORITHM; EVOLUTION; NETWORKS; PATTERNS; TRENDS; INDEX -AB The use of bibliometrics is gradually extending to all disciplines. It is particularly suitable for science mapping at a time when the emphasis on empirical contributions is producing voluminous, fragmented, and controversial research streams. Science mapping is complex and unwieldly because it is multi-step and frequently requires numerous and diverse software tools, which are not all necessarily freeware. Although automated workflows that integrate these software tools into an organized data flow are emerging, in this paper we propose a unique open-source tool, designed by the authors, called bibliometrix, for performing comprehensive science mapping analysis. bibliometrix supports a recommended workflow to perform bibliometric analyses. As it is programmed in R, the proposed tool is flexible and can be rapidly upgraded and integrated with other statistical R-packages. It is therefore useful in a constantly changing science such as bibliometrics. (c) 2017 Elsevier Ltd. All rights reserved. -C1 [Aria, Massimo] Univ Napoli Federico II, Dept Econ & Stat, Via Cintia, I-80126 Naples, Italy. - [Cuccurullo, Corrado] Univ Campania Luigi Vanvitelli, Dept Econ & Management, Capua, CE, Italy. -C3 University of Naples Federico II; Universita della Campania Vanvitelli -RP Aria, M (corresponding author), Univ Napoli Federico II, Dept Econ & Stat, Via Cintia, I-80126 Naples, Italy. -EM aria@unina.it; corrado.cuccurullo@unicampania.it -RI ; Aria, Massimo/O-7983-2015 -OI CUCCURULLO, Corrado/0000-0002-7401-8575; Aria, - Massimo/0000-0002-8517-9411 -CR Alavifard S., 2015, HINDEXCALCULATOR H I - [Anonymous], ANAL DONNESS ANAL CO - [Anonymous], 2016, SCIENTOTEXT TEXT SCI - [Anonymous], 2009, Science of Science (Sci2) Tool - [Anonymous], 11 INT C SCI TECHN I - [Anonymous], J AM SOC INFORM SCI - Bailón-Moreno R, 2006, J AM SOC INF SCI TEC, V57, P949, DOI 10.1002/asi.20362 - Bar-Ilan J, 2008, SCIENTOMETRICS, V74, P257, DOI 10.1007/s11192-008-0216-y - Börner K, 2003, ANNU REV INFORM SCI, V37, P179, DOI 10.1002/aris.1440370106 - Briner R. 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Informetr. -PD NOV -PY 2017 -VL 11 -IS 4 -BP 959 -EP 975 -DI 10.1016/j.joi.2017.08.007 -PG 17 -WC Computer Science, Interdisciplinary Applications; Information Science & - Library Science -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Computer Science; Information Science & Library Science -GA FQ0DK -UT WOS:000418020600003 -HC Y -HP N -DA 2025-07-11 -ER - -PT J -AU Mazlee, MN - Zunairah, H -AF Mazlee, M. N. - Zunairah, H. -TI Science mapping of catalyst support for gas adsorption applications -SO ADVANCES IN MATERIALS RESEARCH-AN INTERNATIONAL JOURNAL -LA English -DT Article -DE catalyst supports; gas adsorption; keywords; science mapping -AB Science mapping is a visual representation of the structure and dynamics of scholarly knowledge. Gas adsorption on catalyst supports is a crucial process in many catalytic reactions. The R package "Bibliometrix" and VosViewer software were employed for science mapping analysis. The results show that the upward trend but fluctuates from year to year for both annual scientific production and average article citations per year. Co -occurrence of the keywords were used to identify the primary fields of study and to map the existing state of research. Trending topics reveal some interesting features that support the growth of research in this field and are associated with emerging disciplines or areas of study that have not been extensively explored. -C1 [Mazlee, M. N.] Univ Malaysia Perlis, Fac Mech Engn & Technol, Arau 02600, Perlis, Malaysia. - [Mazlee, M. 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Res. -PD JUN -PY 2024 -VL 13 -IS 3 -SI SI -BP 203 -EP 210 -DI 10.12989/amr.2024.13.3.203 -PG 8 -WC Materials Science, Multidisciplinary -WE Emerging Sources Citation Index (ESCI) -SC Materials Science -GA ZX2L2 -UT WOS:001278518200001 -DA 2025-07-11 -ER - -PT J -AU Souza, LRD - da Silva, DH - Ribeiro, CT - da Silva, DA - Nasuto, SJ - Sweeney-Reed, CM - Andrade, AD - Pereira, AA -AF Souza, Leandro Rodrigues da Silva - da Silva, Daniel Hilario - Ribeiro, Caio Tonus - da Silva, Daiane Alves - Nasuto, Slawomir J. - Sweeney-Reed, Catherine M. - Andrade, Adriano de Oliveira - Pereira, Adriano Alves -TI PubMedMetaTool: Automated metadata extraction from PubMed using Python - for bibliometric analysis -SO SOFTWARE IMPACTS -LA English -DT Article -DE PubMed; Bibliometric analysis; Bibliometric database; Science mapping; - Bibliometrix; VoSViewer -AB Bibliometric analyses often depend on extracting metadata from large scientific databases, a process that is still largely manual, repetitive, and error prone. This paper presents PubMedMetaTool, an open-source Python-based solution that automates the retrieval and transformation of bibliographic metadata from PubMed, using either article titles or Digital Object Identifiers as input. The tool implements a modular pipeline that extracts metadata using NCBI's Entrez programming utilities and transforms it into formats compatible with tools such as Bibliometrix, VOSviewer, and pyBibX. Designed to be transparent and configurable, the tool improves bibliometric workflow efficiency, accuracy, and interoperability workflows. -C1 [Souza, Leandro Rodrigues da Silva; da Silva, Daniel Hilario; Ribeiro, Caio Tonus; Andrade, Adriano de Oliveira; Pereira, Adriano Alves] Programa Posgrad Engn Biomed, Uberlandia, Brazil. - [da Silva, Daniel Hilario] Inst Fed Goiano Campus Cristalina, Cristalina, Brazil. - [Souza, Leandro Rodrigues da Silva] Inst Fed Goiano Campus Rio Verde, Rio Verde, Brazil. - [Andrade, Adriano de Oliveira; Pereira, Adriano Alves] Fac Engn Elect, Uberlandia, Brazil. - [da Silva, Daiane Alves] Programa Posgrad Estudo Literario, Uberlandia, Brazil. - [Nasuto, Slawomir J.] Otto von Guericke Univ, Dept Neurol, Neurocybernet & Rehabil, Magdeburg, Germany. - [Sweeney-Reed, Catherine M.] Univ Reading, Sch Biol Sci, Biomed Sci & Biomed Engn Div, Reading, England. -C3 Instituto Federal de Goias (IFG); Otto von Guericke University; - University of Reading -RP Souza, LRD (corresponding author), Inst Fed Goiano Campus Rio Verde, Rio Verde, Brazil. -EM leandro.souza@ifgoiano.edu.br -RI Silva, Daniel/JWO-9082-2024; Tonus, Caio/LLK-6351-2024; Sweeney-Reed, - Catherine/ADB-1879-2022 -FU National Council for Scientific and Technological Development (CNPq); - Coordination for the Improvement of Higher Education Personnel (CAPES); - Foundation for Research Support of the State of Minas Gerais (FAPEMIG); - CNPq, Brazil [302942/2022-0, 309525/2021-7] -FX The present study was carried out with the support of the National - Council for Scientific and Technological Development (CNPq) , - Coordination for the Improvement of Higher Education Personnel (CAPES) , - along with the Foundation for Research Support of the State of Minas - Gerais (FAPEMIG) . A.O.A. (302942/2022-0) and A.A.P. (309525/2021-7) are - fellows of CNPq, Brazil. We express our gratitude to the Michael J. Fox - Foundation (MJFF) for promoting public awareness of the scientific - research derived from data fostered by the foundation, to Centre for - Innovation and Technology Assessment in Health (NIATS) , Federal - University of Uberlandia, Brazil, and to the Federal Institute of - Education, Science, and Technology Goiano (IF Goiano) - Campus Rio - Verde, Campus Cristalina and the Center of Excellence in Exponential - Agriculture-CEAGRE, the Goias State Research Support Foundation (FAPEG) - , for structural support to conduct this study. -CR Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Arruda H, 2022, J MED LIBR ASSOC, V110, P392, DOI 10.5195/jmla.2022.1434 - Bramley R, 2023, DATABASE-OXFORD, V2023, DOI 10.1093/database/baad070 - Consortium of Academic and Research Libraries in Illinois (CARLI), 2024, PMID key CARLI I-share electronic resource management - Ellegaard O, 2015, SCIENTOMETRICS, V105, P1809, DOI 10.1007/s11192-015-1645-z - Hogue CWV, 1996, TRENDS BIOCHEM SCI, V21, P226, DOI 10.1016/S0968-0004(96)80021-1 - Mrozek D, 2013, BMC BIOINFORMATICS, V14, DOI 10.1186/1471-2105-14-73 - National Center for Biotechnology Information (NCBI), 2017, New API keys for the Eutilities - Ostell J., 2003, NCBI HDB - Oyewola DO, 2022, SN APPL SCI, V4, DOI 10.1007/s42452-022-05027-7 - Pereira V., 2023, arXiv, DOI [10.1108/DTA-08-2023-0461, DOI 10.1108/DTA-08-2023-0461] - Sayers E, 2010, Entrez programming utilities help - Souza L.R. da S., 2024, J. 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Resil. Infrastruct. -PD MAR 4 -PY 2025 -VL 10 -IS 2 -BP 119 -EP 135 -DI 10.1080/23789689.2024.2365502 -EA JUN 2024 -PG 17 -WC Engineering, Civil -WE Emerging Sources Citation Index (ESCI) -SC Engineering -GA 0NK6F -UT WOS:001254076500001 -DA 2025-07-11 -ER - -PT J -AU Yu, JY - Muñoz-Justicia, J -AF Yu, Jingyuan - Munoz-Justicia, Juan -TI A Bibliometric Overview of Twitter-Related Studies Indexed in Web of - Science -SO FUTURE INTERNET -LA English -DT Article -DE twitter; bibliometric analysis; science mapping; bibliometrix -ID TOOL -AB Twitter has been one of the most popular social network sites for academic research; the main objective of this study was to update the current knowledge boundary surrounding Twitter-related investigations and, further, identify the major research topics and analyze their evolution across time. A bibliometric analysis has been applied in this article: we retrieved 19,205 Twitter-related academic articles from Web of Science after several steps of data cleaning and preparation. The R package "Bibliometrix" was mainly used in analyzing this content. Our study has two sections, and performance analysis contains 5 categories (Annual Scientific Production, Most Relevant Sources, Most Productive Authors, Most Cited Publications, Most Relevant Keywords.). The science mapping included country collaboration analysis and thematic analysis. We highlight our thematic analysis by splitting the whole bibliographic dataset into three temporal periods, thus a thematic evolution across time has been presented. This study is one of the most comprehensive bibliometric overview in analyzing Twitter-related studies by far. We proceed to explain how the results will benefit the understanding of current academic research interests on the social media giant. -C1 [Yu, Jingyuan; Munoz-Justicia, Juan] Univ Autonoma Barcelona, Dept Social Psychol, Barcelona 08193, Spain. -C3 Autonomous University of Barcelona -RP Yu, JY (corresponding author), Univ Autonoma Barcelona, Dept Social Psychol, Barcelona 08193, Spain. -EM jingyuan.yu@e-campus.uab.cat; Juan.Munoz@uab.cat -RI Munoz Justicia, Juan/M-1136-2014; Justicia, Juan/M-1136-2014 -OI Munoz Justicia, Juan/0000-0002-7782-9306; Yu, - Jingyuan/0000-0002-9400-4859; -FU Department of Social Psychology, Universitat Autonoma de Barcelona -FX The APC was funded by the Department of Social Psychology, Universitat - Autonoma de Barcelona. -CR Ahmed W., 2017, Using Twitter as a Data Source: An Overview of Ethical, Legal, and Methodological Challenges, P79, DOI [10.1108/s2398-601820180000002004, DOI 10.1108/S2398-601820180000002004] - [Anonymous], 2017, COMPUT SCI ELECTR - [Anonymous], 2003, TATuP-Zeitschrift fur Technikfolgenabschatzung in Theorie und Praxis - [Anonymous], 2018, APPL INTELL, DOI [10.1007/s10489-017-1105-y., DOI 10.1007/s10489-017-1105-y, DOI 10.1007/S10489-017-1105-Y] - [Anonymous], REASON TWITTERS LOSI - [Anonymous], TWITT ANN REP 2018 - [Anonymous], TWITT NOW LOS US US - [Anonymous], 2016, METALS BASEL, DOI DOI 10.3390/MET6090199 - Aragon P, 2013, POLICY INTERNET, V5, P183, DOI 10.1002/1944-2866.POI327 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Atzori L, 2012, COMPUT NETW, V56, P3594, DOI 10.1016/j.comnet.2012.07.010 - Beomil Kang, 2014, [Journal of the Korean Society for Information Management, 정보관리학회지], V31, P293, DOI 10.3743/KOSIM.2014.31.3.293 - Bollen J, 2011, J COMPUT SCI-NETH, V2, P1, DOI 10.1016/j.jocs.2010.12.007 - Börner K, 2003, ANNU REV INFORM SCI, V37, P179, DOI 10.1002/aris.1440370106 - BROADUS RN, 1987, SCIENTOMETRICS, V12, P373, DOI 10.1007/BF02016680 - Buccafurri F, 2015, COMPUT HUM BEHAV, V52, P87, DOI 10.1016/j.chb.2015.05.045 - CALLON M, 1991, SCIENTOMETRICS, V22, P155, DOI 10.1007/BF02019280 - Ceron A, 2016, NEW MEDIA SOC, V18, P1935, DOI 10.1177/1461444815571915 - Chatfield AT, 2013, GOV INFORM Q, V30, P377, DOI 10.1016/j.giq.2013.05.021 - Clarivate Analytics, KEYWORDS PLUS GEN CR - Cobo MJ, 2012, J AM SOC INF SCI TEC, V63, P1609, DOI 10.1002/asi.22688 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - Das D, 2018, ADV INTELL SYST, V710, P339, DOI 10.1007/978-981-10-7871-2_33 - Fausto S., 2016, HDB TWITTER FOR RES, P242, DOI 10.5281/zenodo.44882 - Fung ICH, 2014, LANCET, V384, P2207, DOI 10.1016/S0140-6736(14)62418-1 - Gutiérrez C, 2015, 2015 SCIENCE AND INFORMATION CONFERENCE (SAI), P371, DOI 10.1109/SAI.2015.7237170 - Hernandez-Suarez A, 2019, SENSORS-BASEL, V19, DOI 10.3390/s19071746 - Holmberg Kim, 2014, Scientometrics, V101, P1027, DOI 10.1007/s11192-014-1229-3 - Isa D, 2018, SOC MEDIA SOC, V4, DOI 10.1177/2056305118760807 - Jacobson J, 2016, SOC MEDIA SOC, V2, DOI 10.1177/2056305116637103 - Jaharudin MH, 2014, KAJI MALAYS, V32, P149 - Kwak HG, 2010, INT CONF ADV COMMUN, P591 - Leopold E, 2004, HANDBOOK OF QUANTITATIVE SCIENCE AND TECHNOLOGY RESEARCH: THE USE OF PUBLICATION AND PATENT STATISTICS IN STUDIES OF S&T SYSTEMS, P187 - Liao HC, 2018, SUSTAINABILITY-BASEL, V10, DOI 10.3390/su10010166 - Lu X, 2014, SCI REP-UK, V4, DOI 10.1038/srep06773 - Newman MEJ, 2004, PHYS REV E, V69, DOI 10.1103/PhysRevE.69.026113 - Noyons ECM, 1999, J AM SOC INFORM SCI, V50, P115, DOI 10.1002/(SICI)1097-4571(1999)50:2<115::AID-ASI3>3.3.CO;2-A - Peña-López I, 2014, J SPAN CULT STUD, V15, P189, DOI 10.1080/14636204.2014.931678 - Sweileh WM, 2017, BMC MED INFORM DECIS, V17, DOI 10.1186/s12911-017-0476-7 - Thelwall M, 2020, INT J PSYCHOL, V55, P684, DOI 10.1002/ijop.12633 - Thelwall M, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0064841 - Van Eck NJ, 2007, INT J UNCERTAIN FUZZ, V15, P625, DOI 10.1142/S0218488507004911 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - van Eck NJ, 2009, J AM SOC INF SCI TEC, V60, P1635, DOI 10.1002/asi.21075 - Van Raan A. 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It investigates the development of film tourism, identifies five research categories (tourist destination, tourists' film experience, celebrity, film content, and impact of film tourism) by science mapping and content analysis, and proposes five future research directions. It contributes to film tourism research by providing researchers with a solid foundation of film research development and a roadmap for further film tourism research. 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J. Tour. Res. -PD 2025 MAY 30 -PY 2025 -DI 10.1080/10941665.2025.2511783 -EA MAY 2025 -PG 23 -WC Hospitality, Leisure, Sport & Tourism -WE Social Science Citation Index (SSCI) -SC Social Sciences - Other Topics -GA 3GJ6O -UT WOS:001499703500001 -DA 2025-07-11 -ER - -PT J -AU Xiao, ZW - Qin, Y - Xu, ZS - Antucheviciene, J - Zavadskas, EK -AF Xiao, Zhiwen - Qin, Yong - Xu, Zeshui - Antucheviciene, Jurgita - Zavadskas, Edmundas Kazimieras -TI The Journal Buildings: A Bibliometric Analysis (2011-2021) -SO BUILDINGS -LA English -DT Article -DE bibliometrics; science mapping; Scopus; Bibliometrix -AB The journal Buildings was launched in 2011 and is dedicated to promoting advancements in building science, building engineering and architecture. Motivated by its 10th anniversary in 2021, this study aims to develop a bibliometric analysis of the publications of the journal between April 2011 and October 2021. This work analyzes bibliometric performance indicators, such as publication and citation structures, the most cited articles and the leading authors, institutions and countries/regions. Science mappings based on indicators such as the most commonly used keywords, citation and co-citation, and collaboration are also developed for further analysis. In doing so, the work uses the Scopus database to collect data and Bibliometrix to conduct the research. The results show the strong growth of Buildings over time and that researchers from all over the world are attracted by the journal. -C1 [Xiao, Zhiwen; Qin, Yong; Xu, Zeshui] Sichuan Univ, Business Sch, Chengdu 610064, Peoples R China. - [Antucheviciene, Jurgita] Vilnius Gediminas Tech Univ, Dept Construct Management & Real Estate, Sauletekio Al 11, LT-10223 Vilnius, Lithuania. - [Zavadskas, Edmundas Kazimieras] Vilnius Gediminas Tech Univ, Inst Sustainable Construct, Sauletekio Al 11, LT-10223 Vilnius, Lithuania. -C3 Sichuan University; Vilnius Gediminas Technical University; Vilnius - Gediminas Technical University -RP Xu, ZS (corresponding author), Sichuan Univ, Business Sch, Chengdu 610064, Peoples R China. -EM farrah_x@163.com; yongqin_ahsc@163.com; xuzeshui@263.net; - jurgita.antucheviciene@vilniustech.lt; edmundas.zavadskas@vilniustech.lt -RI Zavadskas, Edmundas/Q-6048-2018; Xu, Zeshui/N-8908-2013; Antucheviciene, - Jurgita/W-6112-2018; Zavadskas, Edmundas Kazimieras/Q-6048-2018 -OI Xu, Zeshui/0000-0003-3547-2908; Antucheviciene, - Jurgita/0000-0002-1734-3216; Zavadskas, Edmundas - Kazimieras/0000-0002-3201-949X -FU National Natural Science Foundation of China [72071135, 71771155] -FX FundingThe work was supported by the National Natural Science Foundation - of China (Nos. 72071135 and 71771155). -CR Abhishek, 2021, MARK INTELL PLAN, V39, P979, DOI 10.1108/MIP-03-2021-0085 - Akadiri PO, 2012, BUILDINGS, V2, P126, DOI 10.3390/buildings2020126 - Al-Kodmany K, 2018, BUILDINGS-BASEL, V8, DOI 10.3390/buildings8090127 - Al-Kodmany K, 2018, BUILDINGS-BASEL, V8, DOI 10.3390/buildings8080102 - Al-Kodmany K, 2018, BUILDINGS-BASEL, V8, DOI 10.3390/buildings8020024 - Al-Kodmany K, 2018, BUILDINGS-BASEL, V8, DOI 10.3390/buildings8010007 - Al-Kodmany K, 2014, BUILDINGS, V4, P683, DOI 10.3390/buildings4040683 - Anumba CJ, 2011, BUILDINGS, V1, P1, DOI 10.3390/buildings1010001 - Aria M, 2020, SOC INDIC RES, V149, P803, DOI 10.1007/s11205-020-02281-3 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Asikoglu A, 2021, BUILDINGS-BASEL, V11, DOI 10.3390/buildings11040147 - BROADUS RN, 1987, SCIENTOMETRICS, V12, P373, DOI 10.1007/BF02016680 - Cancino CA, 2017, COMPUT IND ENG, V113, P614, DOI 10.1016/j.cie.2017.08.033 - Cobo MJ, 2015, KNOWL-BASED SYST, V80, P3, DOI 10.1016/j.knosys.2014.12.035 - Fargnoli M, 2020, BUILDINGS-BASEL, V10, DOI 10.3390/buildings10060098 - Fargnoli M, 2019, BUILDINGS-BASEL, V9, DOI 10.3390/buildings9030069 - Guleria D, 2021, LIBR HI TECH, V39, P1001, DOI 10.1108/LHT-09-2020-0218 - KESSLER MM, 1963, AM DOC, V14, P10, DOI 10.1002/asi.5090140103 - Kouris EGS, 2021, BUILDINGS-BASEL, V11, DOI 10.3390/buildings11070296 - Merigó JM, 2019, SOFT COMPUT, V23, P1477, DOI 10.1007/s00500-018-3168-z - Mumu JR, 2021, APPL NURS RES, V59, DOI 10.1016/j.apnr.2020.151334 - Novas N, 2020, ENERGIES, V13, DOI 10.3390/en13246700 - Noyons ECM, 1999, J AM SOC INFORM SCI, V50, P115, DOI 10.1002/(SICI)1097-4571(1999)50:2<115::AID-ASI3>3.3.CO;2-A - Rousseau R, 2014, NATURE, V510, P218, DOI 10.1038/510218e - Sepasgozar SME, 2020, BUILDINGS-BASEL, V10, DOI 10.3390/buildings10120231 - Shehu R, 2021, BUILDINGS-BASEL, V11, DOI 10.3390/buildings11020071 - SMALL H, 1973, J AM SOC INFORM SCI, V24, P265, DOI 10.1002/asi.4630240406 - Tahmasebinia F, 2019, BUILDINGS-BASEL, V9, DOI 10.3390/buildings9060137 - Tahmasebinia F, 2018, BUILDINGS-BASEL, V8, DOI 10.3390/buildings8110165 - Tang M, 2021, J CIV ENG MANAG, V27, P100, DOI 10.3846/jcem.2021.14365 - Vinokurov M, 2019, BUILDINGS-BASEL, V9, DOI 10.3390/buildings9020045 - Vinokurov M, 2018, BUILDINGS-BASEL, V8, DOI 10.3390/buildings8080112 - Wan L, 2017, APPL ENERG, V205, P57, DOI 10.1016/j.apenergy.2017.07.107 - Wang XX, 2020, TRANSPORT-VILNIUS, V35, P557, DOI 10.3846/transport.2020.14140 - Wang XX, 2021, INT J SYST SCI, V52, P1515, DOI 10.1080/00207721.2020.1862937 - Yu DJ, 2019, J CIV ENG MANAG, V25, P402, DOI 10.3846/jcem.2019.9925 - Yu DJ, 2017, INFORM SCIENCES, V418, P619, DOI 10.1016/j.ins.2017.08.031 - Zhou W, 2020, BALT J ROAD BRIDGE E, V15, P1, DOI 10.7250/bjrbe.2020-15.470 -NR 38 -TC 26 -Z9 27 -U1 3 -U2 72 -PU MDPI -PI BASEL -PA MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND -EI 2075-5309 -J9 BUILDINGS-BASEL -JI BUILDINGS-BASEL -PD JAN -PY 2022 -VL 12 -IS 1 -AR 37 -DI 10.3390/buildings12010037 -PG 16 -WC Construction & Building Technology; Engineering, Civil -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Construction & Building Technology; Engineering -GA ZD8EA -UT WOS:000758427100001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Moroz, D -AF Moroz, David -TI On What Topics Does the Scientific Community Cooperate in Defense - Economics? A Science Mapping of the First 30 Years of the Journal - Defence and Peace Economics -SO DEFENCE AND PEACE ECONOMICS -LA English -DT Article -DE Science mapping; defence and peace economics; SPAR-4-SLR; Scopus; - bibliometrix; F50; H56 -ID EVOLUTION; NETWORK; TOOL -AB The academic journal Defence and Peace Economics, which celebrated its pearl jubilee in 2024, is acknowledged as the leading journal in defense economics, bringing together a scientific community of authors from a diverse array of countries. We conduct a bibliometric study using science mapping to analyze the evolution of author networks and research themes within the journal from 1994 to 2023. Analyzing 1069 articles, our findings reveal a growing internationalization of the journal, alongside an increasing diversification of topics. However, we observe a decrease in the rate of international co-authorship during the most recent period of our analysis, i.e. 2019-2023. 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Peace Econ. -PD MAY 19 -PY 2025 -VL 36 -IS 4 -BP 555 -EP 576 -DI 10.1080/10242694.2024.2377964 -EA JUL 2024 -PG 22 -WC Economics -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA 2OJ6T -UT WOS:001270165100001 -DA 2025-07-11 -ER - -PT J -AU Orastean, R - Marginean, SC -AF Orastean, Ramona - Marginean, Silvia Cristina -TI Renminbi Internationalization Process: A Quantitative Literature Review -SO INTERNATIONAL JOURNAL OF FINANCIAL STUDIES -LA English -DT Review -DE bibliometric analysis; Bibliometrix; Biblioshiny; Chinese currency; - renminbi internationalization; science mapping -ID EXCHANGE-RATE; BIBLIOMETRIC ANALYSIS; BUSINESS; MARKETS -AB As China's position in the global economy has gradually improved, the importance of debates on the role of the renminbi in the international monetary system has significantly increased. This paper uses bibliometric methods-Bibliometrix R-package and its web-based graphical interface Biblioshiny-applied to data imported from Web of Science and Scopus to investigate and synthesize the renminbi literature published in English between 1995 and 2021. Science mapping offers a visual representation of different networks and clusters of authors' keywords. The performance analysis, a quantitative evaluation of the most published sources, authors and papers on renminbi internationalization in the last 25 years, shows that the interest on the topic has grown, particularly after 2009 and 2016, respectively. There is also a high degree of concentration in the field, considering that out of the 802 analyzed papers, published in 393 sources, five authors and four journals had the highest impact. The content analysis identifies the main directions in the renminbi internationalization literature and future research questions to further explore this subject. 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J. Financ. Stud. -PD MAR -PY 2023 -VL 11 -IS 1 -AR 15 -DI 10.3390/ijfs11010015 -PG 25 -WC Business, Finance -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA A7BO6 -UT WOS:000956637500001 -OA Green Published, gold -DA 2025-07-11 -ER - -PT J -AU Sarikoç, GÖ -AF Sarikoc, Gulhan Ozdogan -TI Artificial intelligence applications in the field of streamflow: a - bibliometric analysis of recent trends -SO HYDROLOGICAL SCIENCES JOURNAL -LA English -DT Article -DE artificial intelligence; streamflow; bibliometric; research trends; - Scopus; RStudio Bibliometrix -ID NEURAL-NETWORK; WATER-LEVEL; MODELS; PREDICTION; WAVELET; ALGORITHM; - MACHINE; FLOW; TOOL -AB In this study, a bibliometric analysis technique is used for performance analysis and science mapping of artificial intelligence (AI) applications in streamflow research. This paper examines the current trends in the literature using the Scopus database over the last 37 years. RStudio Bibliometrix software was used to analyse the titles, keywords, abstracts, and full texts of 3000 publications to identify trends in AI models, publication types, journals, citations, authors, countries, and regions. The highest frequency AI-related keyword is "artificial neural networks," which was used in a total of 25587 times. The most common publication type, at 82.1%, is journal articles, and the highest rate of country production is 25% for China. 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Marjanovic, U - Savkovic, M - Rakic, S -AF Ciric, Danijela - Lalic, Bojan - Marjanovic, Ugljesa - Savkovic, Milena - Rakic, Slavko -BE Dolgui, A - Bernard, A - Lemoine, D - VonCieminski, G - Romero, D -TI A Bibliometric Analysis Approach to Review Mass Customization Scientific - Production -SO ADVANCES IN PRODUCTION MANAGEMENT SYSTEMS: ARTIFICIAL INTELLIGENCE FOR - SUSTAINABLE AND RESILIENT PRODUCTION SYSTEMS, PT V -SE IFIP Advances in Information and Communication Technology -LA English -DT Proceedings Paper -CT International-Federation-of-Information-Processing-Working-Group-5.7 - (IFIP WG 5.7) International Conference on Advances in Production - Management Systems (APMS) -CY SEP 05-09, 2021 -CL ELECTR NETWORK -DE Bibliometric analysis; Bibliometrix; Mass customization -ID SCIENCE -AB Mass customization is an important manufacturing concept aimed at integrating product varieties to provide customized services and products based on individual needs. This concept has emerged in the 1980s as demand for product variety increased, and the research in this area has been present for the last three decades. This article aims to study the scientific production around mass customization through metadata analysis of all articles indexed in the bibliographic database Web of Science. The science mapping and bibliometric analysis was conducted using the "bibliometrix" R Package. Also, a graphical analysis of the bibliographic data was performed using VOSviewer software. This study identified the most relevant sources, authors, and countries active and influential through a five-stage workflow consisting of study design, data collection, data analysis, data visualization, and data interpretation. Keyword analysis revealed the related emerging research topics. Co-citation and co-occurrence analysis was performed to underline research streams. -C1 [Ciric, Danijela; Lalic, Bojan; Marjanovic, Ugljesa; Savkovic, Milena; Rakic, Slavko] Univ Novi Sad, Fac Tech Sci, Novi Sad 21000, Serbia. -C3 University of Novi Sad -RP Ciric, D (corresponding author), Univ Novi Sad, Fac Tech Sci, Novi Sad 21000, Serbia. -EM danijela.ciric@uns.ac.rs -RI ; Rakic, Slavko/AAZ-3524-2020; Ciric Lalic, Danijela/AAK-5305-2020; - Lalic, Bojan/AAC-4625-2021; Marjanovic, Ugljesa/N-4620-2018 -OI Ciric Lalic, DANIJELA/0000-0002-4834-6487; Lalic, - Bojan/0000-0002-2202-9352; Rakic, Slavko/0000-0002-9021-8585; Savkovic, - Milena/0000-0003-4270-4383; Marjanovic, Ugljesa/0000-0002-8389-6927 -CR Alon I, 2018, ASIA PAC J MANAG, V35, P573, DOI 10.1007/s10490-018-9597-5 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bashir MF, 2021, ENVIRON SCI POLLUT R, V28, P20700, DOI [10.1007/s11356-020-12123-x, 10.1080/1331677X.2021.1962383] - Ciric D, 2020, IFIP ADV INF COMM TE, V592, P122, DOI 10.1007/978-3-030-57997-5_15 - Da Silveira G, 2001, INT J PROD ECON, V72, P1, DOI 10.1016/S0925-5273(00)00079-7 - Echchakoui S, 2020, J IND INF INTEGR, V20, DOI 10.1016/j.jii.2020.100172 - Ellegaard O, 2015, SCIENTOMETRICS, V105, P1809, DOI 10.1007/s11192-015-1645-z - Jin RY, 2019, RESOUR CONSERV RECY, V140, P175, DOI 10.1016/j.resconrec.2018.09.029 - Merediz-Solà I, 2019, RES INT BUS FINANC, V50, P294, DOI 10.1016/j.ribaf.2019.06.008 - Mongeon P, 2016, SCIENTOMETRICS, V106, P213, DOI 10.1007/s11192-015-1765-5 - Pine II B, 1993, MASS CUSTOMIZATION N - Strozzi F, 2017, INT J PROD RES, V55, P6572, DOI 10.1080/00207543.2017.1326643 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Zawadzki P, 2016, MANAG PROD ENG REV, V7, P105, DOI 10.1515/mper-2016-0030 - Zupic I, 2015, ORGAN RES METHODS, V18, P429, DOI 10.1177/1094428114562629 -NR 15 -TC 6 -Z9 6 -U1 3 -U2 12 -PU SPRINGER INTERNATIONAL PUBLISHING AG -PI CHAM -PA GEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND -SN 1868-4238 -EI 1868-422X -BN 978-3-030-85914-5; 978-3-030-85913-8 -J9 IFIP ADV INF COMM TE -PY 2021 -VL 634 -BP 328 -EP 338 -DI 10.1007/978-3-030-85914-5_35 -PG 11 -WC Computer Science, Information Systems; Engineering, Industrial; - Engineering, Manufacturing; Telecommunications -WE Conference Proceedings Citation Index - Science (CPCI-S) -SC Computer Science; Engineering; Telecommunications -GA BS8PW -UT WOS:000775555100035 -DA 2025-07-11 -ER - -PT J -AU Gozali, I - Syahid, A - Suryati, N -AF Gozali, Imelda - Syahid, Abdul - Suryati, Nunung -TI Ten Years after Sutton (2012): Quo Vadis Feedback Literacy? (A - Bibliometric Study) -SO REGISTER JOURNAL -LA English -DT Article -DE bibliometric; bibliometrix; feedback; feedback literacy; scientometric -ID CORRECTIVE FEEDBACK; SLA -AB Drawing on the construct of Academic Literacy, Paul Sutton coined the term "Feedback Literacy" in 2012. Since then, a growing body of research on Feedback Literacy has emerged from scholars worldwide. This bibliometric study then intended to trace the historical development of Feedback Literacy research over a decade and identify future trends and directions in the field. Extracting from the Scopus database and employing Bibliometrix R tool, this study seeks to reveal the performance analysis and science mapping of the construct. PRISMA 2020 was utilized to guide the articles' search, screening, selection, and reporting. The result of the performance analysis revealed the most prominent journal (Assessment and Evaluation in Higher Education), author (David Carless), article (Carless & Boud, 2018), and keywords (students-related feedback) in feedback literacy research. The conceptual, intellectual, and social structure analyses under science mapping provided insight into popular and fundamental research themes and the collaboration network among feedback literacy authors, with Australian researchers at the forefront. The findings imply that feedback literacy is a fertile ground for further research on topics such as students -related feedback, online feedback, ecological factor, and dialogic feedback. Studies outside of the context of higher education are still under-represented. This study can also aid novice scholars in finding relevant references or outlets for publication. -C1 [Gozali, Imelda; Suryati, Nunung] Univ Negeri Malang, Fac Letters, English Language Educ, Malang 65145, Indonesia. - [Gozali, Imelda] Univ Katolik Widya Mandala Surabaya, Teacher Educ Fac, English Language Educ, Surabaya 60114, Indonesia. - [Syahid, Abdul] Inst Agama Islam Negeri Palangka Raya, Fac Teacher Training & Educ, English Language Educ, Palangka Raya 73112, Indonesia. -C3 Universitas Negeri Malang; Universitas Katolik Widya Mandala Surabaya -RP Gozali, I (corresponding author), Univ Negeri Malang, Fac Letters, English Language Educ, Malang 65145, Indonesia.; Gozali, I (corresponding author), Univ Katolik Widya Mandala Surabaya, Teacher Educ Fac, English Language Educ, Surabaya 60114, Indonesia. -EM Imelda.gozali.2102219@students.um.ac.id -RI Gozali, Imelda/AEG-9489-2022; Syahid, Abdul/AAW-6578-2020; Suryati, - Nunung/NRB-2413-2025 -OI Gozali, Imelda/0000-0003-1276-6452; Syahid, Abdul/0000-0001-7284-4665; - SURYATI, NUNUNG/0000-0002-4672-2952; -CR Agbo FJ, 2021, SMART LEARN ENVIRON, V8, DOI 10.1186/s40561-020-00145-4 - Altamimi OA, 2021, ARAB WORLD ENGL J, V12, P308, DOI 10.24093/awej/vol12no3.21 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Baas J, 2020, QUANT SCI STUD, V1, P377, DOI 10.1162/qss_a_00019 - Barbosa MW, 2023, EDUC REV, V75, P558, DOI 10.1080/00131911.2021.1907314 - Barrot JS, 2021, J EDUC COMPUT RES, V59, P645, DOI 10.1177/0735633120972010 - Black P, 1998, PHI DELTA KAPPAN, V80, P139 - Boud D, 2023, ASSESS EVAL HIGH EDU, V48, P158, DOI 10.1080/02602938.2021.1910928 - Caputo A, 2022, J MARK ANAL, V10, P82, DOI 10.1057/s41270-021-00142-7 - Carless D., 2022, FEEDBACK LITERACY HI - Carless D, 2023, TEACH HIGH EDUC, V28, P150, DOI 10.1080/13562517.2020.1782372 - Carless D, 2018, ASSESS EVAL HIGH EDU, V43, P1315, DOI 10.1080/02602938.2018.1463354 - Chellappandi P. 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Lingkar Salatiga Km. 02, Pulutan, Sidorejo, Salatiga, Central Java, - INDONESIA -SN 1979-8903 -EI 2503-040X -J9 REGIST J -JI REGISTER J. -PY 2023 -VL 16 -IS 1 -BP 139 -EP 167 -DI 10.18326/rgt.v16i1.139-167 -PG 29 -WC Education & Educational Research; Linguistics -WE Emerging Sources Citation Index (ESCI) -SC Education & Educational Research; Linguistics -GA N2XM5 -UT WOS:001035704200007 -DA 2025-07-11 -ER - -PT J -AU Tsilika, K -AF Tsilika, Kyriaki -TI Exploring the Contributions to Mathematical Economics: A Bibliometric - Analysis Using Bibliometrix and VOSviewer -SO MATHEMATICS -LA English -DT Review -DE mathematical economics; Bibliometrix; VOSviewer; bibliometric analysis; - science mapping -ID COURNOT -AB From Cournot, Walras, and Pareto's research to what followed in the form of marginalist economics, chaos theory, agent-based modeling, game theory, and econophysics, the interpretation and analysis of economic systems have been carried out using a broad range of higher mathematics methods. The evolution of mathematical economics is associated with the most productive and influential authors, sources, and countries, as well as the identification of interactions between the authors and research topics. Bibliometric analysis provides journal-, author-, document-, and country-level metrics. In the present study, a bibliometric overview of mathematical economics came from a screening performed in September 2023, covering the timespan 1898-2023. About 6477 documents on mathematical economics were retrieved and extracted from the Scopus academic database for analysis. The Bibliometrix package in the statistical programming language R was employed to perform a bibliometric analysis of scientific literature and citation data indexed in the Scopus database. VOSviewer (version 1.6.19) was used for the visualization of similarities using several bibliometric techniques, including bibliographic coupling, co-citation, and co-occurrence of keywords. The analysis traced the most influential papers, keywords, countries, and journals among high-quality studies in mathematical economics. -C1 [Tsilika, Kyriaki] Sch Econ & Business, Dept Econ, Volos 38221, Greece. - [Tsilika, Kyriaki] Hellen Open Univ, Sch Social Sci, Fac Business Adm, 26222 Patras, Greece. -C3 Hellenic Open University -RP Tsilika, K (corresponding author), Sch Econ & Business, Dept Econ, Volos 38221, Greece.; Tsilika, K (corresponding author), Hellen Open Univ, Sch Social Sci, Fac Business Adm, 26222 Patras, Greece. -EM ktsilika@uth.gr -RI Tsilika, Kyriaki/E-2117-2018 -OI Tsilika, Kyriaki/0000-0002-9213-3120 -CR [Anonymous], 1993, The Development of Mathematical Economics the Years of Transition: From Cournot to Jevons - [Anonymous], 1984, Fundamental Methods of Mathematical Economics - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Arrow KJ, 1954, ECONOMETRICA, V22, P265, DOI 10.2307/1907353 - Baas J, 2020, QUANT SCI STUD, V1, P377, DOI 10.1162/qss_a_00019 - Bar-Ilan J, 2008, J INFORMETR, V2, P1, DOI 10.1016/j.joi.2007.11.001 - BROADUS RN, 1987, SCIENTOMETRICS, V12, P373, DOI 10.1007/BF02016680 - Burnham Judy F, 2006, Biomed Digit Libr, V3, P1 - DEBREU G, 1991, AM ECON REV, V81, P1 - DEBREU G, 1986, ECONOMETRICA, V54, P1259, DOI 10.2307/1914299 - DEBREU G, 1984, SCAND J ECON, V86, P393, DOI 10.2307/3439651 - Debreu G., 1983, Mathematical Economics: Twenty Papers of Gerard Debreu - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Dow SC, 2003, J POST KEYNESIAN EC, V25, P547 - Edgeworth FY, 1915, ECON J, V25, P189, DOI 10.2307/2222169 - Edgeworth F.Y., 1915, I. 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Science mapping via co-authorship analysis elucidates that more collaborative efforts among authors are needed in the future in this field. Bibliographic coupling analysis bifurcates the studies into six clusters and reveals the major themes and their evolution. Co-word analysis unfolds emerging trends that could be further explored, thus becoming possible future research avenues.Originality/value - To the best of the authors' knowledge, no other study has attempted a bibliometric analysis of research on the relationship between IFRS and EM. 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Account. Lit. -PD JAN 2 -PY 2025 -VL 47 -IS 1 -BP 51 -EP 74 -DI 10.1108/JAL-02-2023-0036 -EA OCT 2023 -PG 24 -WC Business, Finance -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA P8L9N -UT WOS:001086377400001 -DA 2025-07-11 -ER - -PT J -AU Yao, X - Xu, ZS - Zizka, M -AF Yao, Xuan - Xu, Zeshui - Zizka, Miroslav -TI TWENTY-FIVE YEARS OF "E&M ECONOMICS AND MANAGEMENT": A BIBLIOMETRIC - ANALYSIS -SO E & M EKONOMIE A MANAGEMENT -LA English -DT Editorial Material -DE E&M; bibliometric analysis; evolution; science mapping; Bibliometrix -ID INFORMATION SCIENCES -AB E&M Economics and Management (E&M), originally founded in 1998, is dedicated to promoting advancements in the fields of Economics and Management based on theoretical and empirical analyses. Motivated by its 25th anniversary in 2023, this paper utilizes bibliometrics to make a comprehensive analysis of publications of the E&M that are included in Social Sciences Edition of the Web of Science (WoS). First, we make a performance analysis of the related publications to present the development and distribution of the E&M publications between January 2008 and April 2022 from the aspects of publication and citation structure. Second, a visual analysis of the literature called science-mapping analysis is implemented to display the structural and dynamic organization of knowledge of the E&M publications with the help of bibliometric tools VOSviewer and Bibliometrix. Finally, the paper discusses the evolution of E&M and some of the limitations and prospects to help editors and researchers understand how E&M has evolved over time and where it can be improved. This paper also provides a model of future effective analytical methods for assessing the data from a particular journal. According to the findings, researchers throughout the world publish in this journal on a regular basis. E&M is growing significantly during twenty-five years, and is becoming one of the influential journals in the fields of Economics and Management. -C1 [Yao, Xuan; Xu, Zeshui] Southeast Univ, Sch Econ & Management, Nanjing, Peoples R China. - [Xu, Zeshui] Sichuan Univ, Business Sch, Chengdu, Peoples R China. - [Zizka, Miroslav] Tech Univ Liberec, Fac Econ, Liberec, Czech Republic. -C3 Southeast University - China; Sichuan University; Technical University - of Liberec -RP Xu, ZS (corresponding author), Southeast Univ, Sch Econ & Management, Nanjing, Peoples R China.; Xu, ZS (corresponding author), Sichuan Univ, Business Sch, Chengdu, Peoples R China. -EM shiny_yao@yeah.net; xuzeshui@263.net; miroslav.zizka@tul.cz -RI Xu, Zeshui/N-8908-2013; Yao, Xuan/JLM-6103-2023; Zizka, - Miroslav/I-5624-2016 -OI Xu, Zeshui/0000-0003-3547-2908; Zizka, Miroslav/0000-0002-7804-3954 -CR Abhishek, 2021, MARK INTELL PLAN, V39, P979, DOI 10.1108/MIP-03-2021-0085 - Belás J, 2015, E M EKON MANAG, V18, P95, DOI 10.15240/tul/001/2015-1-008 - BROADUS RN, 1987, SCIENTOMETRICS, V12, P373, DOI 10.1007/BF02016680 - Dabija DC, 2018, E M EKON MANAG, V21, P191, DOI 10.15240/tul/001/2018-1-013 - Merigó JM, 2019, SOFT COMPUT, V23, P1477, DOI 10.1007/s00500-018-3168-z - Merigó JM, 2018, INFORM SCIENCES, V432, P245, DOI 10.1016/j.ins.2017.11.054 - PRITCHARD A, 1969, J DOC, V25, P348 - Qin Y, 2022, RENEW SUST ENERG REV, V153, DOI 10.1016/j.rser.2021.111780 - Soltés V, 2014, E M EKON MANAG, V17, P100, DOI 10.15240/tul/001/2014-3-009 - Szabo ZK, 2013, E M EKON MANAG, V16, P52 - Tang M, 2021, J CIV ENG MANAG, V27, P100, DOI 10.3846/jcem.2021.14365 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Wang XX, 2020, TRANSPORT-VILNIUS, V35, P557, DOI 10.3846/transport.2020.14140 - Wang XX, 2021, INT J SYST SCI, V52, P1515, DOI 10.1080/00207721.2020.1862937 - Xiao ZW, 2022, BUILDINGS-BASEL, V12, DOI 10.3390/buildings12010037 - Yu DJ, 2019, TECHNOL ECON DEV ECO, V25, P369, DOI 10.3846/tede.2019.10193 - Yu DJ, 2017, INFORM SCIENCES, V418, P619, DOI 10.1016/j.ins.2017.08.031 - Zheng YH, 2021, ACTA MONTAN SLOVACA, V26, P512, DOI 10.46544/AMS.v26i3.10 - Zizka M, 2008, E M EKON MANAG, V11, P6 -NR 19 -TC 1 -Z9 1 -U1 2 -U2 29 -PU TECHNICAL UNIV LIBEREC -PI LIBEREC 1 -PA FAC ECONOMICS, STUDENTSKA 2, IC 46747885, LIBEREC 1, 461 17, CZECH - REPUBLIC -SN 1212-3609 -EI 2336-5064 -J9 E M EKON MANAG -JI E M Ekon. Manag. -PY 2023 -VL 26 -IS 1 -BP 4 -EP 24 -DI 10.15240/tul/001/2023-1-001 -PG 21 -WC Economics; Management -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA 9S0BX -UT WOS:000946012800001 -OA gold, Green Published -DA 2025-07-11 -ER - -PT J -AU Sharma, P - Singh, R - Tamang, M - Singh, AK - Singh, AK -AF Sharma, Primula - Singh, Ranjit - Tamang, Manila - Singh, Amit Kumar - Singh, Akhilesh Kumar -TI Journal of teaching in travel &tourism: a bibliometric analysis -SO JOURNAL OF TEACHING IN TRAVEL & TOURISM -LA English -DT Article -DE Journal of Teaching in Travel & Tourism; bibliometrix; bibliometric - analysis; travel and tourism education -ID HOSPITALITY MANAGEMENT; UNDERGRADUATE TOURISM; STUDENT PERCEPTIONS; - EDUCATION FUTURES; TEFI VALUES; CAREER; INDUSTRY; ENTREPRENEURSHIP; - PERSPECTIVES; EXPECTATIONS -AB Journal of Teaching in Travel & Tourism (JTTT) is a widely acknowledged journal for its contribution to scientific knowledge development in travel and tourism education. Understanding the developmental trajectory of JTTT in the context of tourism and hospitality education is highly relevant for academic research and practice. This study sets out to present the scientific development, productivity, influence, and research trends of JTTT from 2001 to 2019 through bibliometric analysis. A sample of 407 documents extracted from the Scopus database were analysed with techniques such as descriptive, conceptual structure, intellectual structure and social structure analyses. The study uses the scientometric tool "bibliometrix" written in R programming language for science mapping. 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Teach. Travel Tour. -PD APR 3 -PY 2021 -VL 21 -IS 2 -BP 155 -EP 176 -DI 10.1080/15313220.2020.1845283 -EA NOV 2020 -PG 22 -WC Education & Educational Research -WE Emerging Sources Citation Index (ESCI) -SC Education & Educational Research -GA SH6VL -UT WOS:000592713000001 -DA 2025-07-11 -ER - -PT J -AU Khan, D - Verma, MK - Yuvaraj, M -AF Khan, Daud - Verma, Manoj Kumar - Yuvaraj, Mayank -TI Cluster analysis and network visualization of journals, authors, - keywords, and themes of monkeypox research (1989-2022): an updated - bibliometric review -SO LIBRARY HI TECH -LA English -DT Review; Early Access -DE Monkeypox; Web of science; Science mapping; Cluster analysis; Network - analysis; Bibliometric analysis; Bibliometrix; VOS viewer -ID PROTECTS MICE; SMALLPOX VACCINATION; VIRUS-INFECTION; VACCINIA VIRUS; - CONGO; SCIENCE; WEB; PUBLICATIONS; CHALLENGE; OUTBREAK -AB PurposeThere have been numerous publications on human monkeypox since it was reported. With the help of bibliometric analysis, this study examined research hotspots and future trends related to human monkeypox. Science mapping was used in this study to identify influential monkeypox researchers, institutions, articles, keywords, thematic structures, and clusters of articles.Design/methodology/approachBased on a validated search query, bibliometric analysis of data collected from Web of Science from 1989 to September 2022 was conducted. Using the "Title-Keyword-Abstract" search option, the search query consisted of keywords "Monkeypox" OR "Monkeypox virus" OR "monkeypox" OR "monkey pox" OR "MPXV." With the state-of-the-art tools Bibliometrix package of R Studio and VOSviewer, performance analysis and science mapping, as a part of standard bibliometric research of monkeypox research were conducted.FindingsResearchers published 708 monkeypox papers from 1989 to September 2022, with American researchers publishing 460 papers. Further, USA had the highest international cooperation in terms of collaborative research output. Centers for Disease Control and Prevention (CDC) is a global leader in monkeypox research since it is the most prolific and collaborative organization. There have been the most published papers on monkeypox in the Journal of Virology. Damon Inger K is also the most prolific and influential researcher in monkeypox research, with the highest number of publications and citations. In total, 1,679 keywords were identified in the study. From the cluster analysis four themes were identified in monkeypox research. They are (1) clinical features, (2) monkeypox virus epidemiology, (3) monkeypox virus vaccine defense, and (4) monkeypox virus-related treatment measures.Originality/valueAnalysis of collaboration, findings, networks of research, and visualization separates this study from traditional metrics analysis. 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Hi Tech -PD 2023 JUN 22 -PY 2023 -DI 10.1108/LHT-12-2022-0559 -EA JUN 2023 -PG 25 -WC Information Science & Library Science -WE Social Science Citation Index (SSCI) -SC Information Science & Library Science -GA J8GX8 -UT WOS:001011963600001 -DA 2025-07-11 -ER - -PT J -AU Bakir, M - Özdemir, E - Akan, S - Atalik, Ö -AF Bakir, Mahmut - Ozdemir, Emircan - Akan, Sahap - Atalik, Ozlem -TI A bibliometric analysis of airport service quality -SO JOURNAL OF AIR TRANSPORT MANAGEMENT -LA English -DT Article -DE Airport; Service quality; Bibliometric analysis; Bibliometrix; Web of - science -ID TOURISM; PASSENGERS; AIRLINE; MODEL; SATISFACTION; PERCEPTIONS; - HOSPITALITY; ENVIRONMENT; TRENDS; IMPACT -AB Airports have evolved into key business centers in the last four decades, serving a variety of business models in addition to providing transportation infrastructure. Additionally, service quality, which is critical for airports to maintain a competitive edge, is a major area of research in the aviation literature. This study aims to analyze the existing literature on airport service quality through the bibliometric analysis method and to present a perspective on the literature's trajectory. Science mapping techniques and performance analysis were applied in this process. R-based Bibliometrix software was used to investigate 100 studies indexed in the Web of Science (WoS) database between 1975 and 2020. Research findings show that the Journal of Air Transport Management leads the literature in terms of publication performance. Researchers from China offer the highest contribution to the literature as a country. In addition, service quality research has largely resulted from collaboration networks. It is expected that an understanding of the research themes that emerge from the scientific mapping technique will guide researchers. -C1 [Bakir, Mahmut] Samsun Univ, Dept Aviat Management, Istiklal Denizevleri Str, TR-55420 Samsun, Turkey. - [Ozdemir, Emircan; Atalik, Ozlem] Eskisehir Tech Univ, Dept Aviat Management, POB 26555, Eskisehir, Turkey. - [Akan, Sahap] Anadolu Univ, Dept Civil Aviat Management, POB 26170, Eskisehir, Turkey. -C3 Samsun University; Eskisehir Technical University; Anadolu University -RP Bakir, M (corresponding author), Samsun Univ, Dept Aviat Management, Istiklal Denizevleri Str, TR-55420 Samsun, Turkey. -EM mahmut.bakir@samsun.edu.tr -RI BAKIR, Mahmut/O-8875-2019; Atalık, Özlem/G-2472-2019; AKAN, - Şahap/HSB-8408-2023; Özdemir, Emircan/ABB-3642-2020 -OI OZDEMIR, EMIRCAN/0000-0002-1383-4712; atalik, ozlem/0000-0003-2889-6825; - BAKIR, Mahmut/0000-0002-3898-4987; -CR 2021-2039 IATA, 2021, CURR TRENDS - ACI, 2020, ACI World data reveals COVID-19's impact on world's busiest airports - ACI,, 2016, ACI REL NEW RES PAP - ACI,, 2020, ACI INTR NEW AIRP SE - Adler N., 2001, TRANSPORT POLICY, V8, P171 - Ahmad T, 2021, HUM VACC IMMUNOTHER, V17, P2367, DOI 10.1080/21645515.2021.1886806 - Aksit Asik N., 2019, J. 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Manag. -PD SEP -PY 2022 -VL 104 -AR 102273 -DI 10.1016/j.jairtraman.2022.102273 -EA AUG 2022 -PG 14 -WC Transportation -WE Social Science Citation Index (SSCI) -SC Transportation -GA 5Z9NE -UT WOS:000880291200005 -DA 2025-07-11 -ER - -PT C -AU Schirone, M -AF Schirone, Marco -BE Kurbanoglu, S - Spiranec, S - Unal, Y - Boustany, J - Kos, D -TI STEM Information Literacy: A Bibliometric Mapping (1974-2020) -SO INFORMATION LITERACY IN A POST-TRUTH ERA, ECIL 2021 -SE Communications in Computer and Information Science -LA English -DT Proceedings Paper -CT 7th European Conference on Information Literacy (ECIL) -CY SEP 20-23, 2021 -CL ELECTR NETWORK -DE STEM information literacy; STEM; Information literacy; Bibliometric - mapping; Science mapping; Bibliometrics; Sociology of science; - Bibliometrix -ID HIGHER-EDUCATION; SCIENCE; INSTRUCTION; TECHNOLOGY; SKILLS; TOOL -AB This exploratory paper investigates with bibliometric methods the area of research and practice constituted by information literacy in science, technology, engineering, and mathematics (STEM). Amongst the findings are the most central publication channels, authors, and topics. Academic librarianship and library and information science appear as intellectual bases for this field, although a degree of specialisation (particularly towards the health sciences and engineering) also emerges. The findings are discussed in light of Richard Whitley's sociology of science and Annemaree Lloyd's sociocultural approach to information literacy. -C1 [Schirone, Marco] Chalmers Univ Technol, Gothenburg, Sweden. - [Schirone, Marco] Univ Boras, Boras, Sweden. -C3 Chalmers University of Technology; University of Boras -RP Schirone, M (corresponding author), Chalmers Univ Technol, Gothenburg, Sweden.; Schirone, M (corresponding author), Univ Boras, Boras, Sweden. -EM marco.schirone@chalmers.se -RI Schirone, Marco/J-3932-2014 -OI Schirone, Marco/0000-0002-4166-153X -CR Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bawden D, 2001, J DOC, V57, P218, DOI 10.1108/EUM0000000007083 - Bawden D, 2017, J INF SCI, V43, P17, DOI 10.1177/0165551515616919 - Bybee RW, 2010, SCIENCE, V329, P996, DOI 10.1126/science.1194998 - CALLON M, 1991, SCIENTOMETRICS, V22, P155, DOI 10.1007/BF02019280 - Cameron L, 2007, COLL RES LIBR, V68, P229, DOI 10.5860/crl.68.3.229 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - Garfield E, 2004, J INF SCI, V30, P119, DOI 10.1177/0165551504042802 - Gross M, 2009, COLL RES LIBR, V70, P336, DOI 10.5860/crl.70.4.336 - Harris SY, 2017, IFLA J-INT FED LIBR, V43, P171, DOI 10.1177/0340035216684522 - Johnston B, 2003, STUD HIGH EDUC, V28, P335, DOI 10.1080/03075070309295 - Kates RW, 2001, SCIENCE, V292, P641, DOI 10.1126/science.1059386 - Kaufman J., 2019, SCI TECH LIBR, V38, P288, DOI DOI 10.1080/0194262X.2019.1637806 - KESSLER MM, 1963, AM DOC, V14, P10, DOI 10.1002/asi.5090140103 - Kurbanoglu S., 2015, 3 EUR C ECIL 2015, DOI [10.1007/978-3-319-28197-1, DOI 10.1007/978-3-319-28197-1] - Kurbanoglu SS, 2006, J DOC, V62, P730, DOI 10.1108/00220410610714949 - Leckie GJ, 1999, COLL RES LIBR, V60, P9, DOI 10.5860/crl.60.1.9 - Leydesdorff L., 2021, The evolutionary dynamics of discursive knowledge: Communication-theoretical perspectives on an empirical philosophy of science, DOI [10.1007/978-3-030-59951-5, DOI 10.1007/978-3-030-59951-5] - Lloyd A, 2007, INFORM RES, V12 - Phillips M, 2020, PROC FRONT EDUC CONF - Phillips M, 2018, J ACAD LIBR, V44, P705, DOI 10.1016/j.acalib.2018.10.006 - Pinto M, 2020, SCIENTOMETRICS, V124, P1479, DOI 10.1007/s11192-020-03523-4 - Pinto M, 2010, J INF SCI, V36, P86, DOI 10.1177/0165551509351198 - Potkonjak V, 2016, COMPUT EDUC, V95, P309, DOI 10.1016/j.compedu.2016.02.002 - Small RV, 2004, COLL RES LIBR, V65, P96, DOI 10.5860/crl.65.2.96 - Stopar K, 2019, SCIENTOMETRICS, V118, P479, DOI 10.1007/s11192-018-2990-5 - The ALA/ACRL/STS Task Force on Information Literacy for Science and Technology, about us - U. S. Department of Education, about us - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Walraven A, 2008, COMPUT HUM BEHAV, V24, P623, DOI 10.1016/j.chb.2007.01.030 - Whitley R., 2000, The intellectual and social organization of the sciences - Xie Y, 2015, ANNU REV SOCIOL, V41, P331, DOI 10.1146/annurev-soc-071312-145659 - Zurkowski P.G, 1974, Related Paper No. 5 -NR 33 -TC 0 -Z9 0 -U1 3 -U2 8 -PU SPRINGER INTERNATIONAL PUBLISHING AG -PI CHAM -PA GEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND -SN 1865-0929 -EI 1865-0937 -BN 978-3-030-99884-4; 978-3-030-99885-1 -J9 COMM COM INF SC -PY 2022 -VL 1533 -BP 385 -EP 395 -DI 10.1007/978-3-030-99885-1_33 -PG 11 -WC Information Science & Library Science -WE Conference Proceedings Citation Index - Social Science & Humanities (CPCI-SSH) -SC Information Science & Library Science -GA BX5XH -UT WOS:001304500200033 -DA 2025-07-11 -ER - -PT J -AU Ingale, KK - Paluri, RA -AF Ingale, Kavita Karan - Paluri, Ratna Achuta -TI Financial literacy and financial behaviour: a bibliometric analysis -SO REVIEW OF BEHAVIORAL FINANCE -LA English -DT Article -DE Financial literacy; Financial behaviour; Household finance; Bibliometric - analysis; Bibliometrix; Science mapping -ID INFORMATION-SCIENCE; RESEARCH FIELD; EVOLUTION; LIBRARY; DEMAND -AB Purpose Numerous exploratory, conceptual and empirical enquiries on financial behaviour and literacy have been conducted in the areas of economics, finance, business and management. However, no attempt was made to present a comprehensive science mapping of the area so far. Hence, the study intends to elicit the trend in the research field through synthesis of knowledge structures. Design/methodology/approach Bibliometric analysis in the field of financial literacy and financial behaviour was performed on a sample of 1,138 documents based on a scientific search strategy run on the Web of Science database for the period 1985-2020. Biblioshiny, which is a web-based application included in Bibliometrix package developed in R-language (Ariaa and Cuccurullo, 2017), was used for the study. With the help of automated workflow in the software, prominent journals, authors, countries, articles, themes were identified; and citation, co-citation and social network analysis were conducted. Findings Results show that the themes of financial literacy and financial behaviour have evolved over a period of time as an interdisciplinary field. In the initial stages, researchers focused on demographic and socio-economic determinants, but gradually the field embraced topics like behavioural and psychological constructs influencing financial behaviour. Along with conceptual structure, this research reveals the intellectual and social structure of the domain. This study provides important insights on areas that need further investigation. Research limitations/implications The current research is a bibliometric analysis and hence limitations related to such studies are applicable. For future researchers to derive a strong conceptual framework, a systematic review of literature would be helpful. Science mapping for this study is limited to the Web of Science database owing to its wider coverage of good quality journals, structured formats which are compatible with the Bibliometrix software. Practical implications The current study provides important insights on financial literacy and financial behaviour and their inter-linkages. It highlights the most addressed issues in the area and leads towards the prospective areas for research. It informs the future researchers about the emergent themes, contexts and possibilities of collaborations in this area by revealing social and intellectual structure of the domain. Social implications The paper can provide important insights for policy formulation in the areas of financial education and literacy. Originality/value There has been lot of conceptual and empirical work done in the past, across countries, spanning the disciplines such as economics, finance, psychology and consumer behaviour. 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Behav. Finance -PD MAR 2 -PY 2022 -VL 14 -IS 1 -BP 130 -EP 154 -DI 10.1108/RBF-06-2020-0141 -EA DEC 2020 -PG 25 -WC Business, Finance -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA ZO5OR -UT WOS:000598622500001 -DA 2025-07-11 -ER - -PT J -AU Aria, M - Alterisio, A - Scandurra, A - Pinelli, C - D'Aniello, B -AF Aria, Massimo - Alterisio, Alessandra - Scandurra, Anna - Pinelli, Claudia - D'Aniello, Biagio -TI The scholar's best friend: research trends in dog cognitive and - behavioral studies -SO ANIMAL COGNITION -LA English -DT Article -DE Dog; Bibliometrix; Behavioral science; Science mapping; Cognition; - Behavior -ID SCIENTIFIC COLLABORATION; LABRADOR RETRIEVERS; CANIS-FAMILIARIS; SOCIAL - COGNITION; NATURAL-HISTORY; DOMESTIC DOGS; SCIENCE; MODEL; TOOL; - SENSITIVITY -AB In recent decades, cognitive and behavioral knowledge in dogs seems to have developed considerably, as deduced from the published peer-reviewed articles. However, to date, the worldwide trend of scientific research on dog cognition and behavior has never been explored using a bibliometric approach, while the evaluation of scientific research has increasingly become important in recent years. In this review, we compared the publication trend of the articles in the last 34 years on dogs' cognitive and behavioral science with those in the general category "Behavioral Science". We found that, after 2005, there has been a sharp increase in scientific publications on dogs. Therefore, the year 2005 has been used as "starting point" to perform an in-depth bibliometric analysis of the scientific activity in dog cognitive and behavioral studies. The period between 2006 and 2018 is taken as the study period, and a backward analysis was also carried out. The data analysis was performed using "bibliometrix", a new R-tool used for comprehensive science mapping analysis. We analyzed all information related to sources, countries, affiliations, co-occurrence network, thematic maps, collaboration network, and world map. The results scientifically support the common perception that dogs are attracting the interest of scholars much more now than before and more than the general trend in cognitive and behavioral studies. Both, the changes in research themes and new research themes, contributed to the increase in the scientific production on the cognitive and behavioral aspects of dogs. Our investigation may benefit the researchers interested in the field of cognitive and behavioral science in dogs, thus favoring future research work and promoting interdisciplinary collaborations. -C1 [Aria, Massimo] Univ Naples Federico II, Dept Econ & Stat, Via Cinthia, I-80126 Naples, Italy. - [Alterisio, Alessandra; Scandurra, Anna; D'Aniello, Biagio] Univ Naples Federico II, Dept Biol, Via Cinthia, I-80126 Naples, Italy. - [Pinelli, Claudia] Univ Campania Luigi Vanvitelli, Dept Environm Biol & Pharmaceut Sci & Technol, Caserta, Italy. -C3 University of Naples Federico II; University of Naples Federico II; - Universita della Campania Vanvitelli -RP D'Aniello, B (corresponding author), Univ Naples Federico II, Dept Biol, Via Cinthia, I-80126 Naples, Italy. -EM biagio.daniello@unina.it -RI Aria, Massimo/O-7983-2015; Alterisio, Alessandra/E-2348-2017; D'Aniello, - Biagio/N-5287-2019; Pinelli, Claudia/AAF-3627-2019; Scandurra, - Anna/AAC-2887-2020 -OI Aria, Massimo/0000-0002-8517-9411; Pinelli, Claudia/0000-0002-1845-9886; - D'ANIELLO, BIAGIO/0000-0002-1176-946X; -FU Universita degli Studi di Napoli Federico II within the CRUI-CARE - Agreement -FX Open access funding provided by Universita degli Studi di Napoli - Federico II within the CRUI-CARE Agreement.. 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This article aims to clarify the status and map the research trends in the field of household waste recycling. Bibliometric analysis is performed using bibliometrix based on publications during 1991-2020 in the Web of Science database. Results show that academic output in this field is growing rapidly. The top contributing authors, countries, institutions, and journals are identified. Collaboration network of authors, institutions, and countries are created and visualized. The most influential and cited articles in this field mainly focus on factors influencing residents' recycling behavior from the perspectives of sociopsychology and economics. The theory of planned behavior is the most widely used psychological model. Other research hotspots include electronic waste, source separation, life cycle assessment, sustainability, organic waste, and circular economy. 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VOSviewer; Bibliomertix R-package -ID ROAD-TRAFFIC INJURIES; STREET-CROSSING DECISIONS; MOTOR-VEHICLE - COLLISIONS; AGE-RELATED DIFFERENCES; SOCIAL FORCE MODEL; FRONT-END - DESIGN; MOBILE PHONE USE; BUILT ENVIRONMENT; CROWD DYNAMICS; SIGNALIZED - INTERSECTIONS -AB Due to the high volume of documents in the pedestrian safety field, the current study conducts a systematic bibliometric analysis on the researches published before October 3, 2021, based on the science-mapping approach. Science mapping enables us to present a broad picture and comprehensive review of a significant number of documents using co-citation, bibliographic coupling, collaboration, and co-word analysis. To this end, a dataset of 6311 pedestrian safety papers was collected from the Web of Science Core Collection database. First, a descriptive analysis was carried out, covering whole yearly publications, most-cited papers, and most productive authors, as well as sources, affiliations, and countries. In the next steps, science mapping was implemented to clarify the social, intellectual, and conceptual structures of pedestrian-safety research using the VOSviewer and Bibliometrix R-package tools. Remarkably, based on intellectual structure, pedestrian safety demonstrated an association with seven research areas: "Pedestrian crash frequency models", "Pedestrian injury severity crash models", "Traffic engineering measures in pedestrians' safety", "Global reports around pedestrian accident epidemiology", "Effect of age and gender on pedestrians' behavior", "Distraction of pedestrians", and "Pedestrian crowd dynamics and evacuation". Moreover, according to conceptual structure, five major research fronts were found to be relevant, namely "Collision avoidance and intelligent transportation systems (ITS)", "Epidemiological studies of pedestrian injury and prevention", "Pedestrian road crossing and behavioral factors", "Pedestrian flow simulation", and "Walkable environment and pedestrian safety". Finally, "autonomous vehicle", "pedestrian detection", and "collision avoidance" themes were identified as having the greatest centrality and development degrees in recent years. -C1 [Mirhashemi, Ali; Amirifar, Saeideh; Kashani, Ali Tavakoli] Iran Univ Sci & Technol, Sch Civil Engn, Tehran, Iran. - [Mirhashemi, Ali; Amirifar, Saeideh; Kashani, Ali Tavakoli] Iran Univ Sci & Technol, Rd Safety Res Ctr, Tehran, Iran. - [Zou, Xin] Monash Univ, Inst Transport Studies, Clayton, Vic 3800, Australia. -C3 Iran University Science & Technology; Iran University Science & - Technology; Monash University -RP Kashani, AT (corresponding author), Iran Univ Sci & Technol, Sch Civil Engn, Tehran, Iran.; Kashani, AT (corresponding author), Iran Univ Sci & Technol, Rd Safety Res Ctr, Tehran, Iran. -EM alitavakoli@iust.ac.ir -RI ; Kashani, Ali/K-3107-2018; Amirifar, Saeideh/JQX-1283-2023 -OI Amirifar, saeideh/0000-0002-8662-8434; -CR Aekbote K, 2003, INT J VEHICLE DES, V32, P28, DOI 10.1504/IJVD.2003.003235 - Aghabayk K, 2021, ACCIDENT ANAL PREV, V151, DOI 10.1016/j.aap.2021.105990 - Akyol G., 2019, P SUMO US C, P101 - Al-Ghamdi AS, 2002, ACCIDENT ANAL PREV, V34, P205, DOI 10.1016/S0001-4575(01)00015-X - Alogaili A, 2022, ANAL METHODS ACCID R, V33, DOI 10.1016/j.amar.2021.100201 - Ameratunga S, 2006, LANCET, V367, P1533, DOI 10.1016/S0140-6736(06)68654-6 - Amoh-Gyimah R, 2016, ACCIDENT ANAL PREV, V93, P147, DOI 10.1016/j.aap.2016.05.001 - [Anonymous], 2013, J. 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Prev. -PD SEP -PY 2022 -VL 174 -AR 106720 -DI 10.1016/j.aap.2022.106720 -EA JUN 2022 -PG 25 -WC Ergonomics; Public, Environmental & Occupational Health; Social - Sciences, Interdisciplinary; Transportation -WE Social Science Citation Index (SSCI) -SC Engineering; Public, Environmental & Occupational Health; Social - Sciences - Other Topics; Transportation -GA 5D1CB -UT WOS:000864686600003 -PM 35700686 -DA 2025-07-11 -ER - -PT J -AU Farooq, R - Durst, S -AF Farooq, Rayees - Durst, Susanne -TI Understanding knowledge hiding in organizations: a bibliometric analysis - of research trends between 2005 and 2022 -SO GLOBAL KNOWLEDGE MEMORY AND COMMUNICATION -LA English -DT Article -DE Knowledge hiding; Knowledge withholding; Withholding knowledge; Hiding - knowledge; Performance analysis; Science mapping; Scopus; Web of - Science; Bibliometrix; Biblioshiny -ID FUTURE-RESEARCH; H-INDEX; CONSEQUENCES; ANTECEDENTS; BEHAVIOR; SCIENCE; - WORKPLACE; IMPACT; TOOL -AB PurposeConsidering the increasing interest devoted to knowledge hiding in the workplace and academic research, the aim of this study is to analyze the existing literature on knowledge hiding to understand and trace how it has evolved over time and to uncover emerging areas for future research. Design/methodology/approachThe study used performance analysis and science mapping to analyze a sample of 243 studies published between 2005 and 2022. The study focused on analyzing the scientific productivity of articles, themes and authors. FindingsThe results of performance and science mapping analysis indicate that the concept of knowledge hiding behavior evolved recently and a majority of the studies have been conducted in the past decade. The study found that knowledge hiding is still in its infancy and has been studied in relation to other themes such as knowledge sharing, knowledge management, knowledge withholding and knowledge transfer. The study identified emerging themes, productive authors and countries, affiliations, collaboration network of authors, countries and institutions and co-occurrence of keywords. Originality/valueCompared to the recent developments in the knowledge hiding behavior, the present study is more comprehensive in terms of the methods and databases used. 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Commun. -PD JUN 4 -PY 2025 -VL 74 -IS 5/6 -BP 1677 -EP 1723 -DI 10.1108/GKMC-04-2023-0133 -EA JUL 2023 -PG 47 -WC Information Science & Library Science -WE Emerging Sources Citation Index (ESCI) -SC Information Science & Library Science -GA 3IE4U -UT WOS:001026399500001 -DA 2025-07-11 -ER - -PT J -AU Omer, AAA - Zhang, FX - Li, M - Zhang, XY - Zhao, F - Ma, WH - Liu, W -AF Omer, Altyeb Ali Abaker - Zhang, Fangxin - Li, Ming - Zhang, Xinyu - Zhao, Feng - Ma, Wenhui - Liu, Wen -TI Understanding Trends, Influences, Intellectual Structures, and Future - Directions in Agrivoltaic Systems Research: A Bibliometric and Thematic - Analysis -SO WORLD -LA English -DT Review -DE agrivoltaic systems; renewable energy; sustainable agriculture; - bibliometric analysis; VOSviewer and Bibliometrix; co-citation analysis; - thematic clusters; food-energy-water nexus; climate adaptation; - photovoltaic technologies -ID PHOTOVOLTAIC PANELS; PARTIAL SHADE; PRODUCTIVITY; GREENHOUSES; LAND -AB Agrivoltaic (AV) systems have emerged as a transformative solution to global challenges in food-energy-water security, climate resilience, and sustainable land use. The purpose of this study is to analyze trends, influences, intellectual structures, and future research directions in AV systems research from 2011 to 2023. Using a bibliometric approach guided by the PRISMA framework, 477 documents from the Scopus database were analyzed through performance analysis and science mapping with Bibliometrix and VOSviewer. Key findings reveal exponential growth in research output, with the United States, France, and Germany leading in publications, citations, and international collaboration. Eight thematic clusters were identified, including dual productivity of land use, renewable energy integration, policy implications, and climate adaptation. Influential contributors, such as Joshua M. Pearce, and leading journals, including Applied Energy, shape the field. Emerging areas focus on advanced photovoltaic materials and integrated resource management strategies. This study provides a comprehensive roadmap for advancing AV systems research by identifying critical trends, proposing innovative solutions, and fostering interdisciplinary collaborations. Despite limitations, such as database dependency, this analysis highlights AV systems' transformative potential to achieve global sustainability goals. -C1 [Omer, Altyeb Ali Abaker; Zhao, Feng] Puer Univ, Sch Tea & Coffee, Puer 665000, Peoples R China. - [Omer, Altyeb Ali Abaker; Li, Ming; Zhang, Xinyu; Liu, Wen] Univ Sci & Technol China, Sch Phys Sci, Hefei 230026, Peoples R China. - [Zhang, Fangxin; Liu, Wen] Univ Sci & Technol China, Inst Adv Technol, Hefei 230094, Peoples R China. - [Ma, Wenhui] Yunnan Univ, Sch Engn, Kunming 650500, Peoples R China. - [Ma, Wenhui] Puer Univ, Sch Sci & Technol, Puer 665000, Peoples R China. -C3 Pu'er University; Chinese Academy of Sciences; University of Science & - Technology of China, CAS; Chinese Academy of Sciences; University of - Science & Technology of China, CAS; Yunnan University; Pu'er University -RP Omer, AAA (corresponding author), Puer Univ, Sch Tea & Coffee, Puer 665000, Peoples R China.; Omer, AAA; Liu, W (corresponding author), Univ Sci & Technol China, Sch Phys Sci, Hefei 230026, Peoples R China.; Liu, W (corresponding author), Univ Sci & Technol China, Inst Adv Technol, Hefei 230094, Peoples R China. -EM ali1144770@gmail.com; fxzhang2004@163.com; mingxin@ustc.edu.cn; - zxy94@ustc.edu.cn; zhaofeng@peu.edu.cn; mwhsilicon@126.com; - wenliu@ustc.edu.cn -RI Ali Abaker Omer, Altyeb/JAC-0852-2023; ALI ABAKER OMER, - ALTYEB/JAC-0852-2023 -OI Ali Abaker Omer, Altyeb/0000-0001-9420-9910; -FU National Key Research and Development Programme Project - [2023YFE0126400]; Plan for Anhui Major Provincial Science & Technology - Project [202203a06020002]; Fundamental Research Funds for the Central - Universities [WK2030000074]; Science & Technology Program of Hebei - [22327215D] -FX This work was financially supported by the "National Key Research and - Development Programme Project [grant number 2023YFE0126400]", "the Plan - for Anhui Major Provincial Science & Technology Project" [grant number - 202203a06020002], "the Fundamental Research Funds for the Central - Universities" [grant number WK2030000074], and the "Science & Technology - Program of Hebei" under [grant number 22327215D]. -CR Adeh EH, 2019, SCI REP-UK, V9, DOI 10.1038/s41598-019-47803-3 - Adeh EH, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0203256 - Agostini A, 2021, APPL ENERG, V281, DOI 10.1016/j.apenergy.2020.116102 - Agyekum EB, 2024, SUSTAIN ENERGY TECHN, V72, DOI 10.1016/j.seta.2024.104055 - Amaducci S, 2018, APPL ENERG, V220, P545, DOI 10.1016/j.apenergy.2018.03.081 - Andrew AC, 2021, FRONT SUSTAIN FOOD S, V5, DOI 10.3389/fsufs.2021.659175 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Barron-Gafford GA, 2019, NAT SUSTAIN, V2, P848, DOI 10.1038/s41893-019-0364-5 - Bhatnagar S, 2022, RENEW SUST ENERG REV, V162, DOI 10.1016/j.rser.2022.112405 - Blanco Muriel M.J., 2023, P AGRIVOLTAICS2023 C - Chalgynbayeva A, 2023, ENERGIES, V16, DOI 10.3390/en16020611 - Charles M, 2022, bioRxiv, DOI [10.1101/2022.03.10.482833, 10.1101/2022.03.10.482833, DOI 10.1101/2022.03.10.482833] - Chen J, 2022, INT J ENV RES PUB HE, V19, DOI 10.3390/ijerph192214702 - Choi CS, 2023, EARTHS FUTURE, V11, DOI 10.1029/2023EF003542 - Choi CS, 2021, RENEW SUST ENERG REV, V151, DOI 10.1016/j.rser.2021.111610 - Chowdhury Raihan, 2023, 2023 IEEE 11th Region 10 Humanitarian Technology Conference (R10-HTC), P946, DOI 10.1109/R10-HTC57504.2023.10461931 - Dinesh H, 2016, RENEW SUST ENERG REV, V54, P299, DOI 10.1016/j.rser.2015.10.024 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Dupraz C, 2011, RENEW ENERG, V36, P2725, DOI 10.1016/j.renene.2011.03.005 - Efremov Cristina, 2022, 2022 International Conference and Exposition on Electrical And Power Engineering (EPE), P556, DOI 10.1109/EPE56121.2022.9959839 - Elamri Y, 2018, AGR WATER MANAGE, V208, P440, DOI 10.1016/j.agwat.2018.07.001 - Gao Y, 2019, APPL ENERG, V233, P424, DOI 10.1016/j.apenergy.2018.10.019 - Giri NC, 2023, SUSTAIN COMPUT-INFOR, V40, DOI 10.1016/j.suscom.2023.100915 - Goetzberger A., 1982, International Journal of Solar Energy, V1, P55, DOI DOI 10.1080/01425918208909875 - Goodell JW, 2021, J BEHAV EXP FINANC, V32, DOI 10.1016/j.jbef.2021.100577 - Gorjian S, 2022, RENEW SUST ENERG REV, V158, DOI 10.1016/j.rser.2022.112126 - Haddout A., 2024, Proceedings of The 2nd International Conference on Climate Change and Ocean Renewable Energy - Huang K, 2023, ELECTRONICS-SWITZ, V12, DOI 10.3390/electronics12051221 - Huang K, 2020, IEEE ACCESS, V8, P76300, DOI 10.1109/ACCESS.2020.2988663 - Joy SS, 2023, HELIYON, V9, DOI 10.1016/j.heliyon.2023.e17824 - Kandpal Rohan, 2022, ECS Transactions, V107, P8133, DOI 10.1149/10701.8133ecst - Kannan N., 2023, Global Energy Scenario with a Special Reference to Solar Systems for Sustainable Environment, V1st ed. - Katsikogiannis OA, 2022, APPL ENERG, V309, DOI 10.1016/j.apenergy.2021.118475 - Kim Y, 2023, J CLEAN PROD, V420, DOI 10.1016/j.jclepro.2023.138307 - Kini GP, 2021, ADV FUNCT MATER, V31, DOI 10.1002/adfm.202007931 - Kirimura Masaaki, 2022, Environmental Control in Biology, V60, P117, DOI 10.2525/ecb.60.117 - Ko DY, 2023, AGRONOMY-BASEL, V13, DOI 10.3390/agronomy13102625 - Kumar S, 2022, TECHNOL FORECAST SOC, V178, DOI 10.1016/j.techfore.2022.121599 - Li M, 2021, CHIN OPT LETT, V19, DOI 10.3788/COL202119.112201 - Liang Y., 2022, Energy Eng. 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They have been presented as a panacea to the economic and social challenges facing many cities and traditional shopping districts. However, a comprehensive overview of the academic literature on this form of local governance remains to be conducted. Drawing on bibliometric methods and bibliometrix R-tool, this paper maps and examines the state-of-the-art of academic knowledge on BIDs published between 1979 and 2021. Findings suggest that (i) scientific production has increased since the early 2000s, has crossed US borders but remains highly Anglo-Saxon-centered; (ii) academic knowledge on BIDs is multidisciplinary and has been published in high-impact journals; (iii) influential documents on BIDs have centered on three issues: urban governance/politics, policy mobilities-mutation and impacts assessment and criticisms; (iv) while author collaboration networks exist, the interaction between them is limited; (v) the conceptualization of BIDs has changed over time, both in thematic and geographical focus. These results constitute the first science mapping on the academic literature on BIDs, and we argue they should inform future scientific debates about the studying of this form of local governance. -C1 [Silva, Diogo Gaspar; Cachinho, Herculano] Univ Lisbon, Ctr Geog Studies, Inst Geog & Spatial Planning, P-1600276 Lisbon, Portugal. - [Ward, Kevin] Univ Manchester, Dept Geog, Manchester Urban Inst, Manchester M13 9PL, Lancs, England. -C3 Universidade de Lisboa; University of Manchester -RP Silva, DG (corresponding author), Univ Lisbon, Ctr Geog Studies, Inst Geog & Spatial Planning, P-1600276 Lisbon, Portugal. -EM diogosilva4@campus.ul.pt; hc@campus.ul.pt; kevin.ward@manchester.ac.uk -RI ; Cachinho, Herculano/T-9357-2019 -OI Gaspar Silva, Diogo/0000-0001-5142-7176; Cachinho, - Herculano/0000-0003-2238-0967 -FU Fundacao para a Ciencia e a Tecnologia, I.P [2020.06080.BD, - PTDC/GES-URB/31878/2017]; Fundação para a Ciência e a Tecnologia - [PTDC/GES-URB/31878/2017, 2020.06080.BD] Funding Source: FCT -FX This research was funded by Fundacao para a Ciencia e a Tecnologia, - 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Belciu, A - Popescu, ME -AF Crisan, Georgiana-Alina - Belciu, Anda - Popescu, Madalina Ecaterina -TI Digital Transformation-One Step Further to a Sustainable Economy: The - Bibliometric Analysis -SO SUSTAINABILITY -LA English -DT Article -DE digitalization; economic sustainability; sustainable development; - bibliometric analysis; Web of Science; Scopus; Bibliometrix; pyBibX -ID DEVELOPMENT GOALS -AB Digitalization has significantly reshaped human and social life worldwide, serving as a powerful enabler of a sustainable economy, while being directly aligned with Sustainable Development Goal 9, among others. The literature on digitalization and sustainability boosted since 2017, confirming its importance. Unlike most previous studies, this paper extracted articles from both the Scopus and Web of Science platforms, and the bibliometric analysis was conducted using the new Python library, pyBibX, for the cleaned concatenated dataset, as well as Bibliometrix in R for the parallel analysis on the two platforms. We conducted both a performance analysis to measure scientific impact and citations in the quest to better understand the research field and also a science mapping to visually represent the scientific research and its development. Our findings suggest that Sustainability is the main journal with published articles on digitalization and sustainability, whereas China has the largest number of papers in the field and collaborations between countries. Finally, by applying Natural Language Processing, we identified as best topics: digital, sustainable, development, sustainability, digitalization, study, research, transformation, innovation, and model. Moreover, we dug deeper into policy implications to show how these findings could serve policymakers and stakeholders in academia and industry. -C1 [Crisan, Georgiana-Alina; Belciu, Anda; Popescu, Madalina Ecaterina] Bucharest Univ Econ Studies, Fac Econ Cybernet Stat & Informat, 15-17 Dorobanti St,Sect 1, Bucharest 010552, Romania. - [Popescu, Madalina Ecaterina] Natl Sci Res Inst Labour & Social Protect, 6-8 Povernei St, Bucharest 010643, Romania. -C3 Bucharest University of Economic Studies -RP Popescu, ME (corresponding author), Bucharest Univ Econ Studies, Fac Econ Cybernet Stat & Informat, 15-17 Dorobanti St,Sect 1, Bucharest 010552, Romania.; Popescu, ME (corresponding author), Natl Sci Res Inst Labour & Social Protect, 6-8 Povernei St, Bucharest 010643, Romania. -EM crisangeorgiana18@stud.ase.ro; anda.belciu@ie.ase.ro; - madalina.andreica@csie.ase.ro -RI Crisan, Georgiana/KVY-6791-2024; Popescu, Madalina - Ecaterina/AAK-8233-2020; Belciu, Anda/D-1663-2012 -OI Belciu (Velicanu), Anda/0000-0002-6438-1370; -CR Al-Negrish F., 2024, Int. 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To accomplish this, the authors collected 1282 documents from the Web of Science and performed performance analysis and science mapping with the help of the Bibliometrix package in Rstudio. The performance analysis used a range of bibliometric indicators such as productivity, citations, h-index, and m-quotient, in order to identify research trends and the most influential journals, authors, countries, and literature in the study. Science mapping used author keywords co-occurrence, co-authorship, and cocitation analysis to reflect the conceptual, social, and intellectual structure of the research. Specifically, we have seen an exponential increase in the use of text mining in management in recent years. The United States is the dominant country for research, having the earliest studies and the highest number of literature and citations. Furthermore, the research themes showed that topic modeling is at the forefront of current text mining research about management. This study will help scholars and management practitioners interested in the intersection of text mining and management to quickly understand the latest advances in research. -C1 [Song, Guandong; Wu, Jiying] Northeastern Univ, Sch Humanities & Law, Shenyang 110167, Liaoning, Peoples R China. - [Wang, Sihui] Soochow Univ, Sch Mus, Suzhou 215127, Peoples R China. -C3 Northeastern University - China; Soochow University - China -RP Wu, JY (corresponding author), Northeastern Univ, Sch Humanities & Law, Shenyang 110167, Liaoning, Peoples R China. -EM lilylove10@21cn.com -FU project of China National Academy of Innovation Strategy "Analysis of - Scientific Research Competency Elements of Outstanding Scientific and - Technological Innovation Talents" [2020020200015] -FX is work was supported by project of China National Academy of Innovation - Strategy "Analysis of Scientific Research Competency Elements of - Outstanding Scientific and Technological Innovation - Talents"(2020020200015). -CR Abrahams AS, 2015, PROD OPER MANAG, V24, P975, DOI 10.1111/poms.12303 - [Anonymous], 2015, DATA SCI J - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Arteaga C, 2020, SAFETY SCI, V132, DOI 10.1016/j.ssci.2020.104988 - Becker B, 2015, J ECON SURV, V29, P917, DOI 10.1111/joes.12074 - Blondel VD, 2008, J STAT MECH-THEORY E, DOI 10.1088/1742-5468/2008/10/P10008 - Cahlik T, 2000, SCIENTOMETRICS, V49, P373, DOI 10.1023/A:1010581421990 - CALLON M, 1983, SOC SCI INFORM, V22, P191, DOI 10.1177/053901883022002003 - Chen XL, 2020, APPL SCI-BASEL, V10, DOI 10.3390/app10062157 - Costas R, 2007, J INFORMETR, V1, P193, DOI 10.1016/j.joi.2007.02.001 - Csajbók E, 2007, SCIENTOMETRICS, V73, P91, DOI 10.1007/s11192-007-1859-9 - Dong LY, 2018, EXPERT SYST APPL, V114, P210, DOI 10.1016/j.eswa.2018.07.005 - DOYLE LB, 1961, J ACM, V8, P553, DOI 10.1145/321088.321095 - Forliano C, 2021, TECHNOL FORECAST SOC, V165, DOI 10.1016/j.techfore.2020.120522 - Garfield E, 2004, J INF SCI, V30, P119, DOI 10.1177/0165551504042802 - Gaviria-Marin M, 2019, TECHNOL FORECAST SOC, V140, P194, DOI 10.1016/j.techfore.2018.07.006 - Giatsoglou M, 2017, EXPERT SYST APPL, V69, P214, DOI 10.1016/j.eswa.2016.10.043 - Glanzel W., 2006, SCI FOCUS, V1, P10 - Grobelnik M., 2002, Proceedings of the ICML-2002 workshop on data mining lessons learned, P34 - Gutiérrez-Salcedo M, 2018, APPL INTELL, V48, P1275, DOI 10.1007/s10489-017-1105-y - Tran HN, 2018, MEMET COMPUT, V10, P3, DOI 10.1007/s12293-017-0228-3 - Hao TY, 2018, SOFT COMPUT, V22, P7875, DOI 10.1007/s00500-018-3511-4 - Harzing AW, 2016, SCIENTOMETRICS, V106, P787, DOI 10.1007/s11192-015-1798-9 - Hirsch JE, 2005, P NATL ACAD SCI USA, V102, P16569, DOI 10.1073/pnas.0507655102 - Huang YF, 2020, EXPERT SYST APPL, V159, DOI 10.1016/j.eswa.2020.113584 - ika J., 2019, Text Mining With Machine learning: Principles and Techniques, DOI DOI 10.1201/9780429469275 - Jones Q, 2004, INFORM SYST RES, V15, P194, DOI 10.1287/isre.1040.0023 - Kelly CD, 2006, TRENDS ECOL EVOL, V21, P167, DOI 10.1016/j.tree.2006.01.005 - Kinney AL, 2007, P NATL ACAD SCI USA, V104, P17943, DOI 10.1073/pnas.0704416104 - Kontopoulos E, 2013, EXPERT SYST APPL, V40, P4065, DOI 10.1016/j.eswa.2013.01.001 - Lee S, 2009, TECHNOVATION, V29, P481, DOI 10.1016/j.technovation.2008.10.006 - Li N, 2010, DECIS SUPPORT SYST, V48, P354, DOI 10.1016/j.dss.2009.09.003 - Lo S, 2008, EXPERT SYST APPL, V34, P603, DOI 10.1016/j.eswa.2006.09.026 - LUHN HP, 1958, IBM J RES DEV, V2, P159, DOI 10.1147/rd.22.0159 - Mahendhiran PD, 2018, INT J INF TECH DECIS, V17, P883, DOI 10.1142/S0219622018500128 - Martínez-López FJ, 2018, EUR J MARKETING, V52, P439, DOI 10.1108/EJM-11-2017-0853 - Merigó JM, 2015, J BUS RES, V68, P2645, DOI 10.1016/j.jbusres.2015.04.006 - Merigó JM, 2015, APPL SOFT COMPUT, V27, P420, DOI 10.1016/j.asoc.2014.10.035 - Miner G, 2012, PRACTICAL TEXT MINING AND STATISTICAL ANALYSIS FOR NON-STRUCTURED TEXT DATA APPLICATIONS, P1 - Moral-Muñoz JA, 2020, PROF INFORM, V29, DOI 10.3145/epi.2020.ene.03 - Nassirtoussi AK, 2014, EXPERT SYST APPL, V41, P7653, DOI 10.1016/j.eswa.2014.06.009 - Noyons ECM, 1999, J AM SOC INFORM SCI, V50, P115, DOI 10.1002/(SICI)1097-4571(1999)50:2<115::AID-ASI3>3.3.CO;2-A - PETERS HPF, 1991, SCIENTOMETRICS, V20, P235, DOI 10.1007/BF02018157 - Poldrack R. 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Netw. -PD NOV 26 -PY 2021 -VL 2021 -AR 2270276 -DI 10.1155/2021/2270276 -PG 15 -WC Computer Science, Information Systems; Telecommunications -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Computer Science; Telecommunications -GA YW0WE -UT WOS:000753141800001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Bakir, M - Akan, S - Özdemir, E - Han, HS -AF Bakir, Mahmut - Akan, Sahap - Ozdemir, Emircan - Han, Heesup -TI Mapping the intellectual and thematic evolution of airline service - quality research: a bibliometric analysis (1981-2024) -SO JOURNAL OF TRAVEL & TOURISM MARKETING -LA English -DT Article -DE Bibliometric analysis; airline; service quality; Bibliometrix; knowledge - structure -ID CUSTOMER SATISFACTION; BEHAVIORAL INTENTIONS; LOYALTY; PASSENGERS; - PERCEPTIONS; IMPACT; MODEL; TOURISM; BRAND; HOSPITALITY -AB Service quality is paramount in the airline industry, as it directly impacts customer satisfaction, loyalty, and airline profitability. This study conducts the first comprehensive bibliometric analysis of airline service quality research, examining 374 articles (1981-2024) from the Web of Science database. Using the PRISMA protocol, this study conducted performance analysis and science mapping, examining intellectual foundations, thematic evolution, and collaboration patterns. Emerging areas such as machine learning, user-generated content, and sentiment analysis are identified, alongside thematic shifts and methodological advancements. 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Travel Tour. Mark. -PD JUL 24 -PY 2025 -VL 42 -IS 6 -BP 785 -EP 813 -DI 10.1080/10548408.2025.2495572 -PG 29 -WC Hospitality, Leisure, Sport & Tourism -WE Social Science Citation Index (SSCI) -SC Social Sciences - Other Topics -GA 4NJ1X -UT WOS:001522127900001 -DA 2025-07-11 -ER - -PT J -AU Kilicoglu, O - Mehmetcik, H -AF Kilicoglu, Ozge - Mehmetcik, Hakan -TI Science mapping for radiation shielding research -SO RADIATION PHYSICS AND CHEMISTRY -LA English -DT Article -DE Radiation shielding; Bibliometric analysis; Scientometrics; Citation - analysis -ID MECHANICAL-PROPERTIES; BIBLIOMETRICS -AB This article examines intellectual, conceptual, and social networks among academics, organizations, and countries, as well as quantifies the scientific production, assesses scientific quality and impacts in the field of radiation shielding. To this end, we use a bibliometric analysis to evaluate the radiation shielding publication record. The bibliographic search is carried out in the ISI Web of Science, and time span covers documents written from 2000 to 2020. Along with descriptive statistical tools, we utilize the R package "Bibliometrix" as a tool to perform bibliometric analysis in order to model networks among authors, articles, resources, references, keywords, institutions and countries. This investigation reveals substantial radiation shielding publishing trends, especially in terms of co-authorships, citations, institutional cooperation and author country of origin. -C1 [Kilicoglu, Ozge] Uskudar Univ, Vocat Sch Hlth Serv, Dept Nucl Technol & Radiat Protect, Istanbul, Turkey. - [Mehmetcik, Hakan] Marmara Univ, Istanbul, Turkey. -C3 Uskudar University; Marmara University -RP Kilicoglu, O (corresponding author), Uskudar Univ, Vocat Sch Hlth Serv, Dept Nucl Technol & Radiat Protect, Istanbul, Turkey. -EM ozgekoglu@gmail.com -RI ; kilicoglu, ozge/B-9648-2018 -OI MEHMETCIK, HAKAN/0000-0002-1882-4003; -CR Andrés A, 2009, MEASURING ACADEMIC RESEARCH: HOW TO UNDERTAKE A BIBLIOMETRIC STUDY, P1 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bornmann L., 2008, ETHICS SCI ENV POLIT, V8, P93, DOI DOI 10.3354/ESEP00084 - Ellegaard O, 2015, SCIENTOMETRICS, V105, P1809, DOI 10.1007/s11192-015-1645-z - Issa SAM, 2019, COMPOS PART B-ENG, V167, P231, DOI 10.1016/j.compositesb.2018.12.029 - Issa SAM, 2019, MATER CHEM PHYS, V223, P209, DOI 10.1016/j.matchemphys.2018.10.064 - LAWANI SM, 1981, LIBRI, V31, P294 - Li R, 2017, COMPOS SCI TECHNOL, V143, P67, DOI 10.1016/j.compscitech.2017.03.002 - Martin BR, 2011, PROMETHEUS, V29, P455, DOI 10.1080/08109028.2011.643540 - Mering M, 2017, SERIALS REV, V43, P41, DOI 10.1080/00987913.2017.1282288 - Moed HF, 2002, NATURE, V415, P731, DOI 10.1038/415731a - Neuhaus C, 2008, J DOC, V64, P193, DOI 10.1108/00220410810858010 - Shultis J.K., 2000, Radiation Shielding, DOI DOI 10.1016/J.NIMA.2013.06.040 - Tishkevich D. I., 2020, IOP Conference Series: Materials Science and Engineering, V848, DOI 10.1088/1757-899X/848/1/012089 - Tishkevich DI, 2018, J ALLOY COMPD, V749, P1036, DOI 10.1016/j.jallcom.2018.03.288 - van Leeuwen TN, 2003, SCIENTOMETRICS, V57, P257, DOI 10.1023/A:1024141819302 - Waltman L, 2011, SCIENTOMETRICS, V87, P467, DOI 10.1007/s11192-011-0354-5 -NR 17 -TC 32 -Z9 32 -U1 0 -U2 32 -PU PERGAMON-ELSEVIER SCIENCE LTD -PI OXFORD -PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND -SN 0969-806X -EI 1879-0895 -J9 RADIAT PHYS CHEM -JI Radiat. Phys. Chem. -PD DEC -PY 2021 -VL 189 -AR 109721 -DI 10.1016/j.radphyschem.2021.109721 -EA JUL 2021 -PG 16 -WC Chemistry, Physical; Nuclear Science & Technology; Physics, Atomic, - Molecular & Chemical -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Chemistry; Nuclear Science & Technology; Physics -GA WA5KP -UT WOS:000702924200001 -DA 2025-07-11 -ER - -PT J -AU Rehman, IU - Wani, JA - Ganaie, SA -AF Rehman, Ikhlaq Ur - Wani, Javaid Ahmad - Ganaie, Shabir Ahmad -TI Gauging the research performance of BRICS in the domain of Library and - Information Science through Performance analysis and Science mapping -SO JOURNAL OF LIBRARIANSHIP AND INFORMATION SCIENCE -LA English -DT Article -DE Bibliometrics; biblioshiny; BRICS; performance analysis; research - trends; science mapping; LIS; VOSviewer -ID BIBLIOMETRIC ANALYSIS; RESEARCH OUTPUT; CO-AUTHORSHIP; SCIENTIFIC - COLLABORATION; RESEARCH PRODUCTIVITY; RESEARCH LANDSCAPE; RELATIVE - INFLUENCE; H-INDEX; TRENDS; COUNTRIES -AB The study gauges the research performance of the BRICS bloc in the field of Library and Information Science (LIS) research using Performance analysis and Science mapping. The Web of Science database is used for the study and articles published between 2013 and 2022 have been selected for analysis. Data analysis and visualisation have been done using the Bibliometrix R package and VOSviewer. The findings reveal an upward trend in publications. Furthermore, China has been the most prolific nation in terms of productivity and impact. Scientometrics is the leading source in terms of publications while the International Journal of Information Management is the most cited source. With regard to author productivity, Zhang Y has the highest number of publications while Lowry PB is the most cited author. Wuhan University is the most productive organization. In terms of collaboration, the USA is the primary partner for the entire BRICS group, particularly China and collaboration among the BRICS isn't as significant as it is with the non-BRICS countries. This study provides insightful information about recent scientific developments in the field of LIS. Additionally, by using this research as a guide, researchers from different fields will be able to analyse how the body of knowledge on a certain subject has evolved over time. 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Libr. Inf. Sci. -PD DEC -PY 2024 -VL 56 -IS 4 -BP 835 -EP 856 -DI 10.1177/09610006231173464 -EA MAY 2023 -PG 22 -WC Information Science & Library Science -WE Social Science Citation Index (SSCI) -SC Information Science & Library Science -GA L9Z9D -UT WOS:001001696600001 -DA 2025-07-11 -ER - -PT J -AU Unaldi, N -AF Unaldi, Nurdan -TI Analysis of child abuse by science mapping method -SO CHILD ABUSE REVIEW -LA English -DT Article -DE bibliometric analysis; child abuse; science mapping -ID BIBLIOMETRIC ANALYSIS; VALIDITY; NETWORK; SYSTEM; TOOL -AB Child abuse is defined as physical and emotional maltreatment, sexual abuse, neglect and exploitation that cause actual or potential harm to the child's health, development, or dignity. Bibliometrics analyses works produced in a particular field, period and region. It is used to determine the studies carried out in any field, their development and changes in the process, and possible trends. The Web of Science Core Collection database was preferred due to the vast amount of high-quality and effective scientific articles accepted in academic environments worldwide. The data obtained from the database were extracted and filtered. The Bibliometrix program was used to perform a bibliometric analysis of the data obtained from the database. In our research, 2684 articles were analysed. The first scientific study on child abuse research was entered into the database in 1980. It was used in 786 sources and 2684 documents between 1980 and 2021. Child Abuse & Neglect is the journal with the most publications, representing 15.05 per cent (404/2684) of the total articles. The publication of articles on child abuse in journals started in the 1980s. An increase was observed in the number of articles published in the following years. -C1 [Unaldi, Nurdan] Child & Adolescent Psychiat Clin, Istanbul, Turkiye. -RP Unaldi, N (corresponding author), Child & Adolescent Psychiat Clin, Istanbul, Turkiye. -EM nunaldi@yaani.com -RI ; ÜNALDI, NURDAN/JPX-2008-2023 -OI Unaldi, Nurdan/0000-0002-7533-2320; -CR [Anonymous], 2021, Child maltreatment - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Austin AE, 2020, CURR EPIDEMIOL REP, V7, P334, DOI 10.1007/s40471-020-00252-3 - BERNSTEIN DP, 1994, AM J PSYCHIAT, V151, P1132, DOI 10.1176/ajp.151.8.1132 - Brown J, 1998, CHILD ABUSE NEGLECT, V22, P1065, DOI 10.1016/S0145-2134(98)00087-8 - CALLON M, 1991, SCIENTOMETRICS, V22, P155, DOI 10.1007/BF02019280 - Chen CM, 2017, J DATA INFO SCI, V2, P1, DOI 10.1515/jdis-2017-0006 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - Egghe L, 2006, SCIENTOMETRICS, V69, P131, DOI 10.1007/s11192-006-0144-7 - Elinder G, 2018, ACTA PAEDIATR, V107, P3, DOI 10.1111/apa.14473 - Flaherty EG, 2008, PEDIATRICS, V122, P611, DOI 10.1542/peds.2007-2311 - Gonzalez D., 2022, Child Abuse and Neglect - HAMPTON RL, 1985, AM J PUBLIC HEALTH, V75, P56, DOI 10.2105/AJPH.75.1.56 - Harzing A.-W., 2012, BUSINESS LEADERSHIP, V1, P101 - Jones R, 2008, PEDIATRICS, V122, P259, DOI 10.1542/peds.2007-2312 - Kamdem JP, 2019, FOOD CHEM, V294, P448, DOI 10.1016/j.foodchem.2019.05.021 - Keenan HT, 2017, BMC PEDIATR, V17, DOI 10.1186/s12887-017-0969-7 - Kurutkan M., 2018, Kalite Prensiplerinin Gorsel Haritalama Teknigine Gore Bibliyometrik Analizi - Li W, 2015, ENVIRON IMPACT ASSES, V50, P158, DOI 10.1016/j.eiar.2014.09.012 - Liu BCC, 2019, INT J LAW PSYCHIAT, V64, P219, DOI 10.1016/j.ijlp.2019.03.007 - Liu WS, 2021, SCIENTOMETRICS, V126, P849, DOI 10.1007/s11192-020-03697-x - Lyu YW, 2020, CHILD YOUTH SERV REV, V116, DOI 10.1016/j.childyouth.2020.105250 - MARSHAKOVA IV, 1973, NAUCH-TEKHN INFORM 2, P3 - MILNER JS, 1984, J CONSULT CLIN PSYCH, V52, P879, DOI 10.1037/0022-006X.52.5.879 - Nasir A, 2020, IEEE ACCESS, V8, P133377, DOI 10.1109/ACCESS.2020.3008733 - OLDS DL, 1986, PEDIATRICS, V78, P65 - Pezeshki A, 2015, EMERGENCY, V3, P81 - Rodrigues SP, 2014, BMJ OPEN, V4, DOI 10.1136/bmjopen-2013-004468 - SAULSBURY FT, 1985, AM J DIS CHILD, V139, P393, DOI 10.1001/archpedi.1985.02140060075033 - Schöggl JP, 2020, RESOUR CONSERV RECY, V163, DOI 10.1016/j.resconrec.2020.105073 - Shi JG, 2020, SCIENTOMETRICS, V124, P2145, DOI 10.1007/s11192-020-03607-1 - Toda H, 2016, PSYCHIAT RES, V236, P142, DOI 10.1016/j.psychres.2015.12.016 - United Nations, 2023, HER EV COUNTR RANKS - van Berkel SR, 2020, CHILD ABUSE NEGLECT, V103, DOI 10.1016/j.chiabu.2020.104439 - van Raan A., 2014, Bibliometrics Use and Abuse in the Review of Research Performance, V87, P17 - Zeanah CH, 2018, J AM ACAD CHILD PSY, V57, P637, DOI 10.1016/j.jaac.2018.06.007 - Zellman G.L., 1990, EDUC EVAL POLICY AN, V12, P41, DOI [DOI 10.3102/01623737012001041, 10.3102/01623737012001041] - Zhang J, 2016, J ASSOC INF SCI TECH, V67, P1068, DOI 10.1002/asi.23468 -NR 38 -TC 0 -Z9 0 -U1 5 -U2 22 -PU WILEY -PI HOBOKEN -PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA -SN 0952-9136 -EI 1099-0852 -J9 CHILD ABUSE REV -JI Child Abus. Rev. -PD JAN -PY 2024 -VL 33 -IS 1 -DI 10.1002/car.2845 -EA SEP 2023 -PG 15 -WC Family Studies; Social Work -WE Social Science Citation Index (SSCI) -SC Family Studies; Social Work -GA MT0L9 -UT WOS:001067847500001 -OA Bronze -DA 2025-07-11 -ER - -PT J -AU Gupta, N - Chakravarty, R -AF Gupta, Nidhi - Chakravarty, Rupak -TI Deciphering the Status of Library and Information Science Research in - BRICS Nations: A Research Visualization Approach -SO JOURNAL OF LIBRARY ADMINISTRATION -LA English -DT Article -DE Bibliometrics; science mapping; network mapping; co-authorship; - conceptual structure; thematic evaluation; BRICS nations; Library & - Information Science Research; VoSviewer; Bibliometrix R package -AB This paper aimed to evaluate the research trends in the discipline of library and information science (US) originating from the group of nations known as the BRICS (Brazil, Russia, India, China, and South Africa). The Web of Science core collection database (WoSCC) has been used to extract the published data during the period 1989-2020. Furthermore, VoSviewer and Bibliometrix R package software have been employed for bibliometric analysis of data and data visualization. Results from data analysis indicate that China has the highest number of publications. There is a positive upward trend in scientific publications and citation patterns. Scientometrics is the most influential journal with the highest number of publications. Wuhan University is the most productive institution. Fourie I (n=233) attains the first rank as the most prolific author based on the highest number of research publications. The overall collaboration rate of LIS publications among BRICS countries is moderate. Deep learning, machine learning, sentiment analysis, altmetrics, and artificial intelligence are the leading topics in LIS research among BRICS nations. The study will be of interest or helpful for researchers and professionals in the LIS research field who are interested in learning more about research trends in US in the BRICS nations. -C1 [Gupta, Nidhi; Chakravarty, Rupak] Panjab Univ, Dept Lib & Informat Sci, Chandigarh 160014, India. -C3 Panjab University -RP Gupta, N (corresponding author), Panjab Univ, Dept Lib & Informat Sci, Chandigarh 160014, India. -EM nidhigupta@pu.ac.in -RI Chakravarty, Rupak/F-4643-2011; gupta, nidhi/HNI-2706-2023; Chakravarty, - Prof.Rupak/F-4643-2011 -OI Chakravarty, Rupak/0000-0001-5046-1663; -CR Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bornmann L, 2015, J ASSOC INF SCI TECH, V66, P1507, DOI 10.1002/asi.23333 - BRICS, 2016, GOA STAT ENV 2 M BRI - BRICS, 2019, BRICS BRASIL 2019 WH - Budd JM, 2015, LIBR INFORM SCI RES, V37, P290, DOI 10.1016/j.lisr.2015.11.001 - Castor K, 2020, MEM I OSWALDO CRUZ, V115, DOI 10.1590/0074-02760190342 - Erfanmanesh M., 2017, WEBOLOGY, V14, P1 - Esfahani H., 2019, International Journal of Data and Network Science, V3, P145, DOI [DOI 10.5267/J.IJDNS.2019.2.007, 10.5267/j.ijdns.2019.2.007] - Hirsch JE, 2005, P NATL ACAD SCI USA, V102, P16569, DOI 10.1073/pnas.0507655102 - Kumar Naresh, 2011, Annals of Library and Information Studies, V58, P228 - Leydesdorff L, 2009, J INFORMETR, V3, P353, DOI 10.1016/j.joi.2009.05.005 - Mangi L.D., 1996, OPEN J SOC SCI, V2, P62, DOI [10.4236/jss.2014.210008, DOI 10.4236/JSS.2014.210008] - Markusova VA, 2012, COLLNET J SCIENTOMET, V6, P61, DOI 10.1080/09737766.2012.10700924 - MOED HF, 1995, SCIENTOMETRICS, V33, P381, DOI 10.1007/BF02017338 - Nolin J, 2010, J DOC, V66, P7, DOI 10.1108/00220411011016344 - Miranda ITP, 2021, SAGE OPEN, V11, DOI 10.1177/21582440211013780 - Singh N, 2009, LIBRI, V59, P55, DOI 10.1515/libr.2009.006 - Tripathi M, 2018, INFORM LEARN SCI, V119, P183, DOI 10.1108/ILS-10-2017-0101 - Upadhyaya P, 2019, STUD HIGH EDUC, V44, P1567, DOI 10.1080/03075079.2018.1455083 - VOSviewer-Visualizing scientific landscapes, 2021, VOSVIEWER VIS SCI LA - Wang XW, 2012, SCIENTOMETRICS, V91, P591, DOI 10.1007/s11192-011-0576-6 - Web of Science, 2013, 12 BRICS SUMM 2013 -NR 22 -TC 4 -Z9 4 -U1 2 -U2 22 -PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD -PI ABINGDON -PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND -SN 0193-0826 -EI 1540-3564 -J9 J LIBR ADM -JI J. Libr. Adm. -PD APR 3 -PY 2022 -VL 62 -IS 3 -BP 404 -EP 418 -DI 10.1080/01930826.2022.2043695 -PG 15 -WC Information Science & Library Science -WE Emerging Sources Citation Index (ESCI) -SC Information Science & Library Science -GA 0J0YB -UT WOS:000779834000009 -OA Green Published -DA 2025-07-11 -ER - -PT J -AU Al-Quaishi, H - Lu, CJ - Alani, WK -AF Al-Quaishi, Helal - Lu, Caijiang - Alani, W. K. -TI Vibration Energy Harvesting: A Bibliometric Analysis of Research Trends - and Challenges -SO JOURNAL OF VIBRATION ENGINEERING & TECHNOLOGIES -LA English -DT Review -DE Vibration energy harvesting (VEH); Bibliometric analysis; VOSviewer; - CiteSpace; Scientific mapping; Research trends -ID RANGE -AB PurposeTo present a comprehensive bibliometric analysis of vibration energy harvesting (VEH) research from 2005 to 2022.MethodologyUtilizing VOSviewer, CiteSpace, Bibliometrix, and Excel for bibliometric and science mapping analysis on a dataset of 284 publications from the Web of Science Core Collection Database.FindingsChina leads in productivity and influence in VEH research, followed by the United States. Key trends include the integration of machine learning and artificial intelligence to enhance VEH device efficiency.ImplicationsProvides insights into the evolution of VEH research, identifies research frontiers, and suggests critical sub-domains for future research. Encourages researchers to consider various perspectives within the field.Originality/ValueOffers a holistic view and critical assessment of global VEH research, highlighting significant contributions, emerging topics, and future challenges. -C1 [Al-Quaishi, Helal; Lu, Caijiang; Alani, W. K.] Southwest Jiaotong Univ, Sch Mech Engn, Chengdu 610031, Peoples R China. -C3 Southwest Jiaotong University -RP Lu, CJ (corresponding author), Southwest Jiaotong Univ, Sch Mech Engn, Chengdu 610031, Peoples R China. -EM eng.helalalquaishi@gmail.com; lucaijiang@swjtu.edu.cn -RI Lu, Caijiang/HHM-9096-2022; Alani, W. 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Vib. Eng. Technol. -PD DEC 1 -PY 2024 -VL 12 -SU 2 -BP 2253 -EP 2281 -DI 10.1007/s42417-024-01533-7 -EA OCT 2024 -PG 29 -WC Engineering, Mechanical; Mechanics -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Engineering; Mechanics -GA P9F4F -UT WOS:001330394600001 -DA 2025-07-11 -ER - -PT J -AU Forliano, C - De Bernardi, P - Yahiaoui, D -AF Forliano, Canio - De Bernardi, Paola - Yahiaoui, Dorra -TI Entrepreneurial universities: A bibliometric analysis within the - business and management domains -SO TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE -LA English -DT Article -DE Entrepreneurial universities; Academic entrepreneurship; Bibliometric - analysis; Bibliometrix; Technology transfer -ID TECHNOLOGY-TRANSFER; ECONOMIC-DEVELOPMENT; 3RD MISSION; H-INDEX; - PERFORMANCE; INNOVATION; COMMERCIALIZATION; CITATION; IMPACT; - ORIENTATION -AB This study presents a bibliometric analysis of scientific publications investigating entrepreneurial universities in the business and management fields. The authors collected 511 documents from the Web of Science and analysed them using Bibliometrix, an RStudio package for performance analysis and science mapping. The study aims to provide an overview of the evolution of research about this topic and describe the structures (i.e., conceptual, social, and intellectual) characterising it. It discusses the results to identify the main areas addressed so far and highlight gaps in the literature, offering avenues for possible future research. The results show that publications on entrepreneurial universities started over 30 years ago and show an increasing trend, more than tripling in the last 10 years. Considering authors and documents as a unit of analysis, the US and Europe perform well in terms of productivity and relevance, but the phenomenon is globally relevant. The contribution to socio-economic development, especially in developing countries, is a hot topic for future studies. Despite increasing production rates, research on this topic remains fragmented, justifying the need for more systematisation. Furthermore, the paper offers policy makers and practitioners a useful baseline for developing entrepreneurial universities and considering their technological, managerial, and organisational implications. -C1 [Forliano, Canio] Univ Palermo, Via Amico Ugo Antonio, I-90134 Palermo, Italy. - [Forliano, Canio; De Bernardi, Paola] Univ Turin, Corso Unione Soviet 218 Bis, I-10134 Turin, Italy. - [Yahiaoui, Dorra] Kedge Business Sch, Rue Antoine Bourdelle, F-13009 Marseille, France. -C3 University of Palermo; University of Turin; Kedge Business School -RP Forliano, C (corresponding author), Univ Palermo, Via Amico Ugo Antonio, I-90134 Palermo, Italy.; Forliano, C (corresponding author), Univ Turin, Corso Unione Soviet 218 Bis, I-10134 Turin, Italy. -EM canio.forliano@unito.it -RI ; DE BERNARDI, PAOLA/I-4807-2018; FORLIANO, CANIO/AAL-9933-2020 -OI FORLIANO, CANIO/0000-0002-6428-1740; -CR Addor N, 2019, WATER RESOUR RES, V55, P378, DOI 10.1029/2018WR022958 - [Anonymous], 2013, J TECHNOL TRANSFER, DOI DOI 10.1007/s10961-012-9281-8 - 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Retailers are one of the largest consumers of global natural and human resources. They have joined the sustainability bandwagon by pledging resources and communicating the same to their target customers for better business positioning. This study aims to analyze the conceptual structure of sustainability in the context of retail enterprises and its role in shaping consumer behavior. Therefore, it leverages bibliometric techniques to elaborate on the productivity and impact of the existing body of knowledge in this area through performance analysis and discover the knowledge clusters through science mapping. The data used for this study were sourced by querying the Scopus database for the intersection of terms related to 'sustainability,' 'retail,' and 'consumer behavior.' Subsequently, they were processed and illustrated using RStudio and the bibliometrix package for R to drive insights in bibliometric summaries, including tables, maps, and networks. 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Res. -PD MAY 27 -PY 2025 -VL 35 -IS 3 -BP 260 -EP 290 -DI 10.1080/09593969.2024.2381066 -EA JUL 2024 -PG 31 -WC Business -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA 3YI8Y -UT WOS:001276990000001 -DA 2025-07-11 -ER - -PT J -AU Sánchez-Núñez, P - Cobo, MJ - Vaccaro, G - Peláez, JI - Herrera-Viedma, E -AF Sanchez-Nunez, Pablo - Cobo, Manuel J. - Vaccaro, Gustavo - Pelaez, Jose Ignacio - Herrera-Viedma, Enrique -TI Citation Classics in Consumer Neuroscience, Neuromarketing and - Neuroaesthetics: Identification and Conceptual Analysis -SO BRAIN SCIENCES -LA English -DT Article -DE Bibliometrix; consumer behaviour; consumer psychology; consumer - neuroscience; H-index; highly cited papers (HCPs); scientometrics; - science mapping analysis; SciMAT -ID HIGHLY CITED PAPERS; H-INDEX; BRAIN; AUTHORSHIP; SCIENCE; PREFERENCE; - RESPONSES; DESIGN; REWARD; FIELD -AB Neuromarketing, consumer neuroscience and neuroaesthetics are a broad research area of neuroscience with an extensive background in scientific publications. Thus, the present study aims to identify the highly cited papers (HCPs) in this research field, to deliver a summary of the academic work produced during the last decade in this area, and to show patterns, features, and trends that define the past, present, and future of this specific area of knowledge. The HCPs show a perspective of those documents that, historically, have attracted great interest from a research community and that could be considered as the basis of the research field. In this study, we retrieved 907 documents and analyzed, through H-Classics methodology, 50 HCPs identified in the Web of Science (WoS) during the period 2010-2019. The H-Classic approach offers an objective method to identify core knowledge in neuroscience disciplines such as neuromarketing, consumer neuroscience, and neuroaesthetics. To accomplish this study, we used Bibliometrix R Package and SciMAT software. This analysis provides results that give us a useful insight into the development of this field of research, revealing those scientific actors who have made the greatest contribution to its development: authors, institutions, sources, countries as well as documents and references. -C1 [Sanchez-Nunez, Pablo] Univ Malaga, Joint PhD Programme Commun, Dept Audiovisual Commun & Advertising, Fac Commun Sci, Malaga 29071, Spain. - [Sanchez-Nunez, Pablo; Vaccaro, Gustavo; Pelaez, Jose Ignacio] Univ Malaga, Ctr Appl Social Res CISA, Malaga 29071, Spain. - [Sanchez-Nunez, Pablo; Vaccaro, Gustavo; Pelaez, Jose Ignacio] Inst Invest Biomed Malaga IBIMA, Malaga 29010, Spain. - [Cobo, Manuel J.] Univ Cadiz, Sch Engn, Dept Comp Sci & Engn, Cadiz 11202, Spain. - [Vaccaro, Gustavo; Pelaez, Jose Ignacio] Univ Malaga, Higher Tech Sch Comp Engn, Dept Languages & Comp Sci, Malaga 29071, Spain. - [Herrera-Viedma, Enrique] Univ Granada, Andalusian Res Inst Data Sci & Computat Intellige, Dept Comp Sci & AI, Granada 18071, Spain. -C3 Universidad de Malaga; Universidad de Malaga; Universidad de Malaga; - Instituto de Investigacion Biomedica de Malaga y Plataforma en - Nanomedicina (IBIMA); Universidad de Cadiz; Universidad de Malaga; - University of Granada -RP Sánchez-Núñez, P (corresponding author), Univ Malaga, Joint PhD Programme Commun, Dept Audiovisual Commun & Advertising, Fac Commun Sci, Malaga 29071, Spain.; Sánchez-Núñez, P (corresponding author), Univ Malaga, Ctr Appl Social Res CISA, Malaga 29071, Spain.; Sánchez-Núñez, P (corresponding author), Inst Invest Biomed Malaga IBIMA, Malaga 29010, Spain. -EM psancheznunez@uma.es; manueljesus.cobo@uca.es; fabianvaccaro@uma.es; - jipelaez@uma.es; viedma@decsai.ugr.es -RI Cobo Martí­n, Manuel Jesús/C-5581-2011; Vaccaro, Gustavo/AAH-6655-2021; - Vaccaro, Gustavo/M-1566-2014; Pelaez Sanchez, Jose Ignacio/O-9450-2016; - Herrera-Viedma, Enrique/C-2704-2008; HERRERA-VIEDMA, - ENRIQUE/C-2704-2008; Pelaez, Jose/O-9450-2016; Cobo, Manuel - Jesus/C-5581-2011 -OI Sanchez Nunez, Pablo/0000-0001-7845-9506; Vaccaro, - Gustavo/0000-0002-2097-2291; Pelaez Sanchez, Jose - Ignacio/0000-0002-2606-3849; Herrera-Viedma, - Enrique/0000-0002-7922-4984; Cobo, Manuel Jesus/0000-0001-6575-803X -FU Programa Operativo FEDER Andalucia [UMA 18-FEDERJA-148] -FX This work was supported by the Programa Operativo FEDER Andalucia - 2014-2020 under Grant UMA 18-FEDERJA-148. -CR Aharon I, 2001, NEURON, V32, P537, DOI 10.1016/S0896-6273(01)00491-3 - Alonso S, 2009, J INFORMETR, V3, P273, DOI 10.1016/j.joi.2009.04.001 - [Anonymous], Quacquarelli Symonds (QS) Asia University Rankings - [Anonymous], 2012, World Economic Outlook Database - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Ariely D, 2010, NAT REV NEUROSCI, V11, P284, DOI 10.1038/nrn2795 - Bank T.W., WORLD BANK ANN REPOR - Baraybar-Fernández A, 2017, COMUNICAR, V25, P19, DOI 10.3916/C52-2017-02 - Blood AJ, 2001, P NATL ACAD SCI USA, V98, P11818, DOI 10.1073/pnas.191355898 - Bond M, 2019, BRIT J EDUC TECHNOL, V50, P12, DOI 10.1111/bjet.12730 - Bornmann L, 2008, J AM SOC INF SCI TEC, V59, P830, DOI 10.1002/asi.20806 - Brown S, 2011, NEUROIMAGE, V58, P250, DOI 10.1016/j.neuroimage.2011.06.012 - Burrell QL, 2007, J INFORMETR, V1, P170, DOI 10.1016/j.joi.2007.01.003 - Cabrerizo FJ, 2017, PROCEDIA COMPUT SCI, V122, P902, DOI 10.1016/j.procs.2017.11.453 - Callen T., 2012, Gross Domestic Product: An Economys All - CALLON M, 1991, SCIENTOMETRICS, V22, P155, DOI 10.1007/BF02019280 - Cascón-Katchadourian J, 2020, REV ESP DOC CIENT, V43, DOI 10.3989/redc.2020.3.1690 - Chatterjee A, 2011, J COGNITIVE NEUROSCI, V23, P53, DOI 10.1162/jocn.2010.21457 - Cobo MJ, 2014, PROCEDIA COMPUT SCI, V31, P567, DOI 10.1016/j.procs.2014.05.303 - Cobo MJ, 2012, J AM SOC INF SCI TEC, V63, P1609, DOI 10.1002/asi.22688 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - Consulting S., 2019, ARWU ACAD RANKING WO - Conway BR, 2013, PLOS BIOL, V11, DOI 10.1371/journal.pbio.1001504 - Croft J, 2011, MIND BRAIN EDUC, V5, P5, DOI 10.1111/j.1751-228X.2011.01103.x - De la Flor-Martínez M, 2016, CLIN ORAL IMPLAN RES, V27, P1317, DOI 10.1111/clr.12749 - Di Zeo-Sánchez DE, 2021, BIOLOGY-BASEL, V10, DOI 10.3390/biology10020104 - Egghe L, 2006, SCIENTOMETRICS, V69, P131, DOI 10.1007/s11192-006-0144-7 - Erlen JA, 1997, J PROF NURS, V13, P262, DOI 10.1016/S8755-7223(97)80097-X - Esfahani H., 2019, International Journal of Data and Network Science, V3, P145, DOI [DOI 10.5267/J.IJDNS.2019.2.007, 10.5267/j.ijdns.2019.2.007] - Ferrer GG, 2018, ENCYCLOPEDIA OF INFORMATION SCIENCE AND TECHNOLOGY, 4TH EDITION, P5767, DOI 10.4018/978-1-5225-2255-3.ch501 - FORTUNATO V.C. 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A science mapping of a multidimensional concept -SO JOURNAL OF AGRICULTURAL ECONOMICS -LA English -DT Article -DE bibliometrix; concept; science mapping; SPAR-4-SLR protocol; terroir -ID GEOGRAPHICAL INDICATIONS; HEDONIC ESTIMATION; WINE; COCITATION; - METHODOLOGY; BORDEAUX; CLIMATE; QUALITY; ORIGIN; SCOPUS -AB Terroir is a pivotal concept in defining collective quality labels for agricultural products, such as geographical appellations. With climate change likely to significantly impact these appellations' delimitations, an in-depth understanding of terroir's various dimensions becomes imperative. Yet, the literature presents diverse and multifaceted definitions of terroir, making it a challenging concept to delineate. Utilising 913 articles from 1986 to 2023 sourced from Scopus and adhering to the SPAR-4-SLR bibliometric protocol, we conducted a science mapping that includes analysis of document co-citation, co-authorship, bibliographical coupling and keyword co-occurrence to elucidate terroir's definitions, research fields and issues. We propose a bibliometric analysis methodology that enables detailed mapping of the concept by disciplinary fields. The proposed methodology is applicable to systematic literature reviews aimed at studying a domain while incorporating the diversity of scientific disciplines in which it is investigated. Our analysis confirms that, in terms of agri-food sectors, the literature predominantly focuses on wine. More specifically, within the fields of business, economics and social sciences, the primary applications of the concept are with respect to geographical indications and climate change. Research conducted in agricultural and biological sciences facilitates a better characterisation of terroirs in terms of microbial characteristics. This increasingly enables a distinction to be made between the soil-i.e., the terroir place-and the quality of agri-food products. 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Agric. Econ. -PD SEP -PY 2024 -VL 75 -IS 3 -BP 889 -EP 913 -DI 10.1111/1477-9552.12607 -EA JUN 2024 -PG 25 -WC Agricultural Economics & Policy; Economics -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Agriculture; Business & Economics -GA C3J1C -UT WOS:001247891100001 -DA 2025-07-11 -ER - -PT J -AU Lobont, OR - Taran, AM - Vatavu, S - Para, I -AF Lobont, Oana-Ramona - Taran, Alexandra-Madalina - Vatavu, Sorana - Para, Iulia -TI Scientific Radiography of Healthcare System Process Efficiency - Digitalisation -SO ZAGREB INTERNATIONAL REVIEW OF ECONOMICS & BUSINESS -LA English -DT Article -DE Health system; Digitalization; Biblioshiny; Bibliometric and visual - analysis -AB Digitalisation remains a complex process in terms of integration into healthcare, a significant challenge worldwide. This study aims to identify the most influential trends in terms of authors, sources, countries, affiliations, and highly engaged documents that significantly contribute to the healthcare system's digitalisation. To perform a comprehensive science mapping analysis, a logical data frame of 336 Web of Science database recent papers published between 2018 and 2022 are analysed using R-Bibliometrix. Our results highlighted throughout a scientific mapping and visual framework that digitalisation of the health-care system is a revolutionary, actual, and pervasive concept, considered a new research area recognised by evolution and consistent growth. Moreover, the results provide different types of networks and highlight the keywords, authors, documents, and countries with the highest interest in the subject of the digitalisation of healthcare. -C1 [Lobont, Oana-Ramona; Vatavu, Sorana] West Univ Timisoara, Fac Econ & Business Adm, Finance Dept, Timisoara, Romania. - [Taran, Alexandra-Madalina] West Univ Timisoara, Doctoral Sch Econ & Business Adm, Timisoara, Romania. - [Para, Iulia] West Univ Timisoara, Fac Econ & Business Adm, Mkt & Int Business Relat Dept, Timisoara, Romania. -C3 West University of Timisoara; West University of Timisoara; West - University of Timisoara -RP Taran, AM (corresponding author), West Univ Timisoara, Doctoral Sch Econ & Business Adm, Timisoara, Romania. -EM alexandra.taran@e-uvt.ro -RI Vatavu, Sorana/HDN-2055-2022; Iulia, Para/AAO-1320-2020; Taran, - Alexandra/HDM-9276-2022; Lobont, Oana/AHA-3609-2022 -FU Romanian Ministry of Education and Research; CNCS - UEFISCDI - [PN-III-P1-1.1-TE-2019-2182] -FX This work was supported by a grant of the Romanian Ministry of Education - and Research, CNCS - UEFISCDI, project number - PN-III-P1-1.1-TE-2019-2182, within PNCDI III. -CR BROADUS RN, 1987, SCIENTOMETRICS, V12, P373, DOI 10.1007/BF02016680 - Chen CM, 2008, DATA KNOWL ENG, V67, P234, DOI 10.1016/j.datak.2008.05.004 - Craciun AF, 2023, MATHEMATICS-BASEL, V11, DOI 10.3390/math11051168 - Crane D., 1972, American Journal of Sociology, V79, P10 - Diodato V., 1994, Dictionary of bibliometrics, V1st ed. - Iyawa GE, 2016, PROCEDIA COMPUT SCI, V100, P244, DOI 10.1016/j.procs.2016.09.149 - Jarvis T, 2020, HEALTH RES POLICY SY, V18, DOI 10.1186/s12961-020-00583-z - Kaminski J., 2011, Canadian Journal of Nursing Informatics, V8 - Luca MM, 2021, FRONT PUBLIC HEALTH, V9, DOI 10.3389/fpubh.2021.728287 - McKee M, 2019, EUR J PUBLIC HEALTH, V29, P3, DOI 10.1093/eurpub/ckz160 - Mougenot B, 2022, ENVIRON DEV SUSTAIN, V24, P1031, DOI 10.1007/s10668-021-01481-2 - Nataliia V., 2021, International Journal of Health Sciences, V5, P429 - PRITCHARD A, 1969, J DOC, V25, P348 - Reich C, 2021, KARDIOLOGE, V15, P153, DOI 10.1007/s12181-021-00466-9 - Rogers E.M., 1962, Diffusion of innovations, DOI DOI 10.1016/J.ENPOL.2017.03.064 - Rousseau D., 2012, The Oxford Handbook of Evidence Based Management - Taran AM, 2022, INT J ENV RES PUB HE, V19, DOI 10.3390/ijerph19094950 - World Health Organization. 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Bus. -PD NOV 1 -PY 2023 -VL 26 -IS 2 -BP 113 -EP 136 -DI 10.2478/zireb-2023-0017 -PG 24 -WC Economics -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA AR4N2 -UT WOS:001120174800008 -OA Green Published, hybrid -DA 2025-07-11 -ER - -PT J -AU Pant, K - Palanisamy, P -AF Pant, Kamlesh - Palanisamy, Parthiban -TI Industry 4.0 in the Perspective of Supply Chain Management: Evolution - and Future Research Agenda -SO ENGINEERING MANAGEMENT JOURNAL -LA English -DT Article -DE Industry 4.0; supply chain management; performance analysis; science - mapping analysis; thematic analysis; Supply Chain Management; Technology - Management -ID BIG DATA; INTELLECTUAL STRUCTURE; BIBLIOMETRIC ANALYSIS; THINGS IOT; - SMART; LOGISTICS; ANALYTICS; FRAMEWORK; INTERNET; CONTEXT -AB With the rise of Industry 4.0 (I4.0), there has been a shift from traditional to digital ways of running businesses by bringing the real and virtual worlds together. This study examines I4.0 literature in Supply chain management (SCM) over the last five years, finds essential research areas and gaps, and suggests a roadmap of new possibilities and opportunities for further research. First, a performance analysis was undertaken in which the most relevant or productive authors, leading journals, and top countries were examined. Second, a science mapping analysis involving citation, co-citation, and keyword analysis was conducted. Third, a thematic analysis was performed in which numerous themes were discussed in the direction of I4.0 in SCM. The authors examined 260 research publications published during the last five years. The authors used the R package bibliometrix, biblioshiny application, and the Vosviewer to visualize the structure of over 19,000 different references. Finally, the paper suggests a framework for implementing I4.0 in the supply chain (SC). 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J. -PD JAN 1 -PY 2025 -VL 37 -IS 1 -BP 52 -EP 70 -DI 10.1080/10429247.2024.2350287 -EA MAY 2024 -PG 19 -WC Engineering, Industrial; Management -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Engineering; Business & Economics -GA Z1V6E -UT WOS:001221152800001 -DA 2025-07-11 -ER - -PT J -AU Lizano-Mora, H - Palos-Sanchez, PR - Aguayo-Camacho, M -AF Lizano-Mora, Henry - Palos-Sanchez, Pedro R. - Aguayo-Camacho, Mariano -TI The Evolution of Business Process Management: A Bibliometric Analysis -SO IEEE ACCESS -LA English -DT Article -DE Business; Organizations; Bibliometrics; Bibliographies; Databases; - Tools; Software; Business process management; science mapping workflow; - bibliometrix; business process reengineering; enterprise resource - planning; customer relationship management -ID PERFORMANCE; SCIENCE -AB This paper will present the research results for the analysis of the presence and evolution of the term Business Process Management (BPM) in the period 2000-2020 using a literature review with bibliometric analysis. This research sought to evaluate the quantity and quality of empirical support for the use of this tool in organizations. This allowed the researchers to acknowledge and confirm this discipline as an important investigation domain with great potential for helping companies achieve strategic alignment between business and information and communication technologies in the future. The Science Mapping Workflow methodology was used with database and search criteria applied to a total of 1,706 articles related to the subject, which resulted in a total of 624 articles selected for further research. This study identifies the journals that have the most publications about BPM. It concludes that the most promising perspectives are the ones related to Management, Framework and Performance. Even though, from a conceptual viewpoint, performance is the most valued perspective. 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To gain insight into the research frontiers and hotspots in energy efficiency and COVID-19, a systematic literature review and bibliometric analysis on economic effects are performed with the help of the bibliometric tools VOSviewer and Bibliometrix. This paper selects all the publications retrieved based on the subject terms in the Web of Science core collection. Firstly, this article performs a performance analysis of related publications to present the development and distribution of energy efficiency and COVID-19 from research areas, relevant sources, and influential articles. Afterward, a visual analysis of the literature called science mapping analysis is implemented to display the structural and dynamic organization of knowledge in energy efficiency and COVID-19 research. In the end, detailed discussions of two research hotspots and some theoretical and practical implications are concluded in the systematic literature review and bibliometric analysis findings, which may contribute to further development for researchers in the field of energy efficiency and eventually propel the progress of society and economy in an all-round way. -C1 [Yao, Xuan; Xu, Zeshui; Wang, Lina] Southeast Univ, Sch Econ & Management, Nanjing 211189, Jiangsu, Peoples R China. - [Xu, Zeshui; Wang, Xinxin] Sichuan Univ, Business Sch, Chengdu 610065, Sichuan, Peoples R China. - [Skare, Marinko] Juraj Dobrila Univ Pula, Fac Econ & Tourism Dr Mijo Mirkov, Preradoviceva 1 1, Pula 52100, Croatia. -C3 Southeast University - China; Sichuan University; University of Juraj - Dobrila Pula -RP Skare, M (corresponding author), Juraj Dobrila Univ Pula, Fac Econ & Tourism Dr Mijo Mirkov, Preradoviceva 1 1, Pula 52100, Croatia. -EM mskare@unipu.hr -RI Skare, Marinko/L-5504-2019; Yao, Xuan/JLM-6103-2023; Škare, - Marinko/L-5504-2019; Xu, Zeshui/N-8908-2013 -OI Skare, Marinko/0000-0001-6426-3692; Yao, Xuan/0000-0002-8549-2096; Wang, - Xinxin/0000-0002-4255-5106; , Lina/0000-0003-2128-4869; Xu, - Zeshui/0000-0003-3547-2908 -FU National Natural Science Foundation of China [72071135, 71971119]; - Scientific Research Foundation of Graduate School of Southeast Univer- - sity [YBPY2034] -FX Authors declare they do not have any competing financial, - professional, or personal interests from other parties. 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Econ. Dev. Econ. -PY 2024 -VL 30 -IS 1 -BP 287 -EP 311 -DI 10.3846/tede.2023.18726 -EA OCT 2023 -PG 25 -WC Economics -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA JA7M9 -UT WOS:001081434200001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Lim, WM - Kumar, S - Donthu, N -AF Lim, Weng Marc - Kumar, Satish - Donthu, Naveen -TI How to combine and clean bibliometric data and use bibliometric tools - synergistically: Guidelines using metaverse research -SO JOURNAL OF BUSINESS RESEARCH -LA English -DT Article -DE Bibliometrics; Bibliometric analysis; Scientometrics; Scientometric - analysis; Performance analysis; Science mapping; Bibliographic coupling; - Co-occurrence analysis; Co-citation analysis; Trend analysis; - Bibliometrix; Biblioshiny; RStudio; VOSviewer; Scopus; Web of Science; - Metaverse -ID VIRTUAL WORLDS; REALITY; FUTURE; QUALITY -AB Bibliometrics (or scientometrics) is a powerful technique to assess the trajectory of scientific research. Building on the Journal of Business Research's seminal guides for bibliometric analysis-i.e., "How to conduct a bibliometric analysis: An overview and guidelines" and "Guidelines for advancing theory and practice through bibliometric research"-and using metaverse research as a case, this article presents in-depth procedural guidelines for (i) combing and cleaning bibliometric data from multiple databases (Scopus and Web of Science) and (ii) conducting bibliometric analysis using multiple tools (bibliometrix and VOSviewer). Besides serving as a guide to harness the potential of bibliometrics for insightful assessments of scientific research, this article provides noteworthy insights into various features of the metaverse. This includes an examination of decentralized systems and the integration of digital assets, alongside innovations, the influence of industrial revolutions, and ethical and sustainable development. The dynamics of digital identity, ownership, and business models are explored in tandem with engagement strategies and multi-disciplinary perspectives of the metaverse. This comprehensive analysis also addresses metaverse challenges, market behaviors, and marketing strategies. 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The women-inclusive cities related (WICR) studies, which have been gaining academic attention since the late 1990s, remain broadly explored yet lack a holistic trajectory and trend study and a precise women-inclusive city concept framework. This study applies bibliometric analysis with R-package Bibliometrix version 3.3.2 and a systematic review of 1144 articles, mapping global trends and providing a framework for women-inclusive city concepts. The findings show that WICR research increased significantly from 1998 to 2022, indicating continuous interest. Gender, women, and politics are the top three most frequent keywords. Emerging research directions are expected to focus on politics, violence, and urban governance. The findings also indicate a clear tendency for researchers from the same geographical backgrounds or regions to co-author papers, suggesting further international collaboration. 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The present review and bibliometric analysis was performed on 5810 documents (1989-2022) from the Scopus database, using VOSviewer and Bibliometrix/Biblioshiny for science mapping. The results show that the field of smart textiles is highly interdisciplinary and dynamic, with an average growth rate of 22% and exponential growth in the last 10 years. Beeby, S.P., and Torah, R.N. have published the highest number of papers, while Wang, Z.L. has the highest number of citations. The leading journals are Sensors, ACS Applied Materials and Interfaces, and Textile Research Journal, while Advanced Materials has the highest number of citations. China is the country with the most publications and the most extensive cooperative relationships with other countries. Research on smart textiles is largely concerned with new materials and technologies, particularly in relation to electronic textiles. Recent research focuses on energy generation (triboelectric nanogenerators, thermoelectrics, Joule heating), conductive materials (MXenes, liquid metal, silver nanoparticles), sensors (strain sensors, self-powered sensors, gait analysis), speciality products (artificial muscles, soft robotics, EMI shielding), and advanced properties of smart textiles (self-powered, self-cleaning, washable, sustainable smart textiles). -C1 [Sajovic, Irena; Kert, Mateja; Podgornik, Bojana Boh] Univ Ljubljana, Fac Nat Sci & Engn, Dept Text Graph Arts & Design, Askerceva Cesta 12, Ljubljana 1000, Slovenia. -C3 University of Ljubljana -RP Sajovic, I (corresponding author), Univ Ljubljana, Fac Nat Sci & Engn, Dept Text Graph Arts & Design, Askerceva Cesta 12, Ljubljana 1000, Slovenia. -EM irena.sajovic@ntf.uni-lj.si; mateja.kert@ntf.uni-lj.si; - bojana.bohpodgornik@ntf.uni-lj.si -RI Sajovic, Irena/ABA-8957-2020 -OI Sajovic, Irena/0000-0002-7600-1830 -FU The authors are very grateful to MDPI-Applied Sciences for the - 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Sci.-Basel -PD SEP -PY 2023 -VL 13 -IS 18 -AR 10489 -DI 10.3390/app131810489 -PG 38 -WC Chemistry, Multidisciplinary; Engineering, Multidisciplinary; Materials - Science, Multidisciplinary; Physics, Applied -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Chemistry; Engineering; Materials Science; Physics -GA S4SE9 -UT WOS:001071074400001 -OA gold, Green Submitted -DA 2025-07-11 -ER - -PT J -AU Tengilimoglu, D - Orhan, F - Tekin, PS - Younis, M -AF Tengilimoglu, Dilaver - Orhan, Fatih - Tekin, Perihan Senel - Younis, Mustafa -TI Analysis of Publications on Health Information Management Using the - Science Mapping Method: A Holistic Perspective -SO HEALTHCARE -LA English -DT Article -DE health information management; electronic records; bibliometric analysis -ID BIBLIOMETRIC ANALYSIS; USER ACCEPTANCE; TECHNOLOGY; RECORDS; CARE; - QUALITY; MODEL; WORK; IMPLEMENTATION; EFFICIENCY -AB Objective: In the age of digital transformation, there is a need for a sustainable information management vision in health. Understanding the accumulation of health information management (HIM) knowledge from the past to the present and building a new vision to meet this need reveals the importance of understanding the available scientific knowledge. With this research, it is aimed to examine the scientific documents of the last 40 years of HIM literature with a holistic approach using science mapping techniques and to guide future research. Methods: This study used a bibliometric analysis method for science mapping. Co-citation and co-occurrence document analyses were performed on 630 academic publications selected from the Web of Science core collection (WoSCC) database using the keyword "Health Information Management" and inclusion criteria. The analyses were performed using the R-based software Bibliometrix (Version 4.0; K-Synth Srl), Python (Version 3.12.1; The Python Software Foundation), and Microsoft (R) Excel (R) 2016. Results: Co-occurrence analyses revealed the themes of personal health records, clinical coding and data quality, and health information management. The HIM theme consisted of five subthemes: "electronic records", "medical informatics", "e-health and telemedicine", "health education and awareness", and "health information systems (HISs)". As a result of the co-citation analysis, the prominent themes were technology acceptance, standardized clinical coding, the success of HISs, types of electronic records, people with HIM, health informatics used by consumers, e-health, e-mobile health technologies, and countries' frameworks and standards for HISs. Conclusions: This comprehensive bibliometric study shows that structured information can be helpful in understanding research trends in HIM. 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We aimed to summarize the performance of BAs in the health sciences. We searched Scopus for BAs in the health sciences published prior to May 10, 2023. All identified studies were included. We performed a BA on these studies in two steps: performance analysis and science mapping. For the performance analysis, various indicators of scientific production were calculated using the bibliometrix R package. For the science mapping, VOSviewer was used to generate a co-authorship network and a keyword co-occurrence network. In total, 5,828 BAs were analyzed. Scientific production has exploded in the last years, with more than 1,500 BAs published in 2022 alone. Scientific impact (i.e. citations) has also been rising, although at a lesser pace. The mean number of citations per year per BA was 1.78. China was the most productive country, publishing more BAs than the nine other most productive countries combined. China paradoxically had a lower number of citations per publication compared with the nine other most productive countries. International collaborations were rare. Common BA themes included oncology, public health, neurosciences, mental health, artificial intelligence, and COVID-19. BAs are increasingly common in the health sciences, but their performance remains limited. More international collaborations and standardized guidelines could help improve their performance, notably the frequency at which they are cited. -C1 [Li, Jimmy; Deacon, Charles] Ctr Hosp Univ Sherbrooke CHUS, Neurol Div, Sherbrooke, PQ, Canada. - [Li, Jimmy; Keezer, Mark Robert] Ctr Rech Ctr Hosp Univ Montreal CRCHUM, Montreal, PQ, Canada. - [Keezer, Mark Robert] Univ Montreal, Dept Neurosci, Montreal, PQ, Canada. - [Keezer, Mark Robert] Univ Montreal, Sch Publ Hlth, Montreal, PQ, Canada. - [Keezer, Mark Robert] Ctr Hosp Univ Montreal CHUM, Div Nephrol, Montreal, PQ, Canada. - [Keezer, Mark Robert] Ctr Hosp Univ Montreal, 1000 Rue St Denis, Montreal, PQ H2X 0C1, Canada. -C3 Universite de Montreal; Universite de Montreal; Universite de Montreal; - Universite de Montreal; Universite de Montreal -RP Keezer, MR (corresponding author), Ctr Hosp Univ Montreal, 1000 Rue St Denis, Montreal, PQ H2X 0C1, Canada. -EM mark.keezer@umontreal.ca -RI Li, Jimmy/AHA-4780-2022 -OI Li, Jimmy/0000-0002-8386-8897 -FU None. -FX None. -CR Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Beall J., 2021, Beall's list of potential predatory journals and publishers - Chen CM, 2006, J AM SOC INF SCI TEC, V57, P359, DOI 10.1002/asi.20317 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Falagas ME, 2008, FASEB J, V22, P338, DOI 10.1096/fj.07-9492LSF - Kokol P, 2021, HEALTH INFO LIBR J, V38, P125, DOI 10.1111/hir.12295 - Raats M. M., 1992, Food Quality and Preference, V3, P89, DOI 10.1016/0950-3293(91)90028-D - Singh VK, 2021, SCIENTOMETRICS, V126, P5113, DOI 10.1007/s11192-021-03948-5 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 -NR 9 -TC 3 -Z9 3 -U1 3 -U2 7 -PU TAYLOR & FRANCIS LTD -PI ABINGDON -PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND -SN 0300-7995 -EI 1473-4877 -J9 CURR MED RES OPIN -JI Curr. Med. Res. Opin. -PD JAN 2 -PY 2024 -VL 40 -IS 1 -BP 97 -EP 101 -DI 10.1080/03007995.2023.2281503 -EA NOV 2023 -PG 5 -WC Medicine, General & Internal; Medicine, Research & Experimental -WE Science Citation Index Expanded (SCI-EXPANDED) -SC General & Internal Medicine; Research & Experimental Medicine -GA EB9F9 -UT WOS:001105684200001 -PM 37938037 -DA 2025-07-11 -ER - -PT J -AU Zhong, S - Yin, XB - Li, XL - Feng, CB - Gao, ZQ - Liao, X - Yang, S - He, SS -AF Zhong, Sen - Yin, Xiaobing - Li, Xiaolan - Feng, Chaobo - Gao, Zhiqiang - Liao, Xiang - Yang, Sheng - He, Shisheng -TI Artificial intelligence applications in bone fractures: A bibliometric - and science mapping analysis -SO DIGITAL HEALTH -LA English -DT Article -DE Artificial intelligence; bone fracture; bibliometric; research trends; - bibliometrix; CiteSpace -ID COMPRESSION FRACTURES; AUTOMATIC DETECTION; CLASSIFICATION; RADIOGRAPHS; - PREDICTION; DIAGNOSIS; ACCURACY; WOMEN; TOOL -AB Background Bone fractures are a common medical issue worldwide, causing a serious economic burden on society. In recent years, the application of artificial intelligence (AI) in the field of fracture has developed rapidly, especially in fracture diagnosis, where AI has shown significant capabilities comparable to those of professional orthopedic surgeons. This study aimed to review the development process and applications of AI in the field of fracture using bibliometric analysis, while analyzing the research hotspots and future trends in the field.Materials and methods Studies on AI and fracture were retrieved from the Web of Science Core Collections since 1990, a retrospective bibliometric and visualized study of the filtered data was conducted through CiteSpace and Bibliometrix R package.Results A total of 1063 publications were included in the analysis, with the annual publication rapidly growing since 2017. China had the most publications, and the United States had the most citations. Technical University of Munich, Germany, had the most publications. Doornberg JN was the most productive author. Most research in this field was published in Scientific Reports. Doi K's 2007 review in Computerized Medical Imaging and Graphics was the most influential paper.Conclusion AI application in fracture has achieved outstanding results and will continue to progress. In this study, we used a bibliometric analysis to assist researchers in understanding the basic knowledge structure, research hotspots, and future trends in this field, to further promote the development of AI applications in fracture. -C1 [Zhong, Sen; Yang, Sheng; He, Shisheng] Tongji Univ, Shanghai Peoples Hosp 10, Spinal Pain Res Inst, Dept Orthoped,Sch Med, Shanghai, Peoples R China. - [Yin, Xiaobing] Tongji Univ, Shanghai Peoples Hosp 10, Nursing Dept, Sch Med, Shanghai, Peoples R China. - [Li, Xiaolan] Nanchang Univ, Sch Stomatol, Fuzhou Med Coll, Fuzhou, Peoples R China. - [Feng, Chaobo; Liao, Xiang] Huazhong Univ Sci & Technol, Union Shenzhen Hosp, Natl Key Clin Pain Med China, 89 Taoyuan Rd, Shenzhen 518052, Peoples R China. - [Gao, Zhiqiang] Tongji Univ, Shanghai East Hosp, Dept Joint Surg, Sch Med, Shanghai, Peoples R China. -C3 Tongji University; Tongji University; Nanchang University; Huazhong - University of Science & Technology; Tongji University -RP Liao, X (corresponding author), Huazhong Univ Sci & Technol, Union Shenzhen Hosp, Natl Key Clin Pain Med China, 89 Taoyuan Rd, Shenzhen 518052, Peoples R China.; Yang, S; He, SS (corresponding author), Tongji Univ, Shanghai Peoples Hosp 10, Spinal Pain Res Inst, Dept Orthoped,Sch Med, 301Yanchang Middle Rd, Shanghai 200072, Peoples R China. -EM digitalxiang@163.com; 2031212@tongji.edu.cn; tjhss7418@tongji.edu.cn -FU National Natural Science Foundation of China [82372442]; Science and - Technology Commission of Shanghai Municipality [23015820300]; Yunnan - Academician Expert Workstation [202205AF150058]; National Key Research - and Development Program of China [2022YFC3602203]; Nanshan District - Health Science and Technology Project [NS2023002] -FX The authors disclosed receipt of the following financial support for the - research, authorship, and/or publication of this article: This work was - funded by the National Natural Science Foundation of China (Grant No. - 82372442), the Science and Technology Commission of Shanghai - Municipality (Grant No.23015820300), Yunnan Academician Expert - Workstation (Grant No. 202205AF150058), the National Key Research and - Development Program of China (Grant No. 2022YFC3602203),and the Nanshan - District Health Science and Technology Project (Grant No. NS2023002). -CR Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Atkinson EJ, 2012, J BONE MINER RES, V27, P1397, DOI 10.1002/jbmr.1577 - Borgström F, 2020, ARCH OSTEOPOROS, V15, DOI 10.1007/s11657-020-0706-y - Burns JE, 2017, RADIOLOGY, V284, P788, DOI 10.1148/radiol.2017162100 - Chen C, 2008, IEEE COMPUT GRAPH, V28, P18, DOI 10.1109/MCG.2008.2 - Chen CM, 2012, EXPERT OPIN BIOL TH, V12, P593, DOI 10.1517/14712598.2012.674507 - De Brijun B, 2006, J AM MED INFORM ASSN, V13, P696, DOI 10.1197/jamia.M1995 - Doi K, 2007, COMPUT MED IMAG GRAP, V31, P198, DOI 10.1016/j.compmedimag.2007.02.002 - Eskinazi I, 2015, MED ENG PHYS, V37, P885, DOI 10.1016/j.medengphy.2015.06.006 - Forth KE, 2020, FRONT MED-LAUSANNE, V7, DOI 10.3389/fmed.2020.591517 - Fortunato S, 2018, SCIENCE, V359, DOI 10.1126/science.aao0185 - Gan KF, 2019, ACTA ORTHOP, V90, P394, DOI 10.1080/17453674.2019.1600125 - Gyftopoulos S, 2019, AM J ROENTGENOL, V213, P506, DOI 10.2214/AJR.19.21117 - Hallas P, 2006, BMC EMERG MED, V6, DOI 10.1186/1471-227X-6-4 - Hardalaç F, 2022, SENSORS-BASEL, V22, DOI 10.3390/s22031285 - He KM, 2015, IEEE I CONF COMP VIS, P1026, DOI 10.1109/ICCV.2015.123 - He YF, 2017, RADIOL MED, V122, P556, DOI 10.1007/s11547-017-0760-8 - Iyer S., IEEE 17 INT S BIOM I, P726 - Jin L, 2020, EBIOMEDICINE, V62, DOI 10.1016/j.ebiom.2020.103106 - Kasai S, 2006, MED PHYS, V33, P4664, DOI 10.1118/1.2364053 - Kavitha MS, 2012, BMC MED IMAGING, V12, DOI 10.1186/1471-2342-12-1 - Kavitha MS, 2016, DENTOMAXILLOFAC RAD, V45, DOI 10.1259/dmfr.20160076 - Kim DH, 2018, CLIN RADIOL, V73, P439, DOI 10.1016/j.crad.2017.11.015 - Lambrechts A, 2022, FRONT ROBOT AI, V9, DOI 10.3389/frobt.2022.840282 - Langerhuizen DWG, 2019, CLIN ORTHOP RELAT R, V477, P2482, DOI 10.1097/CORR.0000000000000848 - Lindsey R, 2018, P NATL ACAD SCI USA, V115, P11591, DOI 10.1073/pnas.1806905115 - Missoum S, 2013, J BONE MINER RES, V28 - Mohamed EI, 2003, ACTA DIABETOL, V40, pS19, DOI 10.1007/s00592-003-0020-3 - Nishiyama KK, 2014, OSTEOPOROSIS INT, V25, P619, DOI 10.1007/s00198-013-2459-6 - Olczak J, 2017, ACTA ORTHOP, V88, P581, DOI 10.1080/17453674.2017.1344459 - Polzer C, 2024, EUR J RADIOL, V173, DOI 10.1016/j.ejrad.2024.111364 - Pranata YD, 2019, COMPUT METH PROG BIO, V171, P27, DOI 10.1016/j.cmpb.2019.02.006 - Scanlan J, 2018, PROCEEDINGS OF 2018 3RD INTERNATIONAL CONFERENCE ON BIOMEDICAL IMAGING, SIGNAL PROCESSING (ICBSP 2018), P93, DOI 10.1145/3288200.3288215 - Singh A, 2017, COMPUT BIOL MED, V91, P148, DOI 10.1016/j.compbiomed.2017.10.011 - Starosolski ZA., C MED IM COMP AID DI - Tomita N, 2018, COMPUT BIOL MED, V98, P8, DOI 10.1016/j.compbiomed.2018.05.011 - Tseng WJ, 2013, BMC MUSCULOSKEL DIS, V14, DOI 10.1186/1471-2474-14-207 - Uysal F, 2021, APPL SCI-BASEL, V11, DOI 10.3390/app11062723 - Wei CJ, 2006, ACTA RADIOL, V47, P710, DOI 10.1080/02841850600806340 - Wigderowitz CA, 2000, OSTEOPOROSIS INT, V11, P840, DOI 10.1007/s001980070042 - Xu Y, 2013, MICROSC RES TECHNIQ, V76, P333, DOI 10.1002/jemt.22171 - Yoo TK, 2013, YONSEI MED J, V54, P1321 - Zhang Y, 2020, INJURY, V51, P407, DOI 10.1016/j.injury.2019.11.029 - Zhao H, 2021, FRONT SURG, V8, DOI 10.3389/fsurg.2021.634629 - Zhou QQ, 2020, KOREAN J RADIOL, V21, P869, DOI 10.3348/kjr.2019.0651 - Zhou X., C PHOT PLUS ULTR IM -NR 46 -TC 1 -Z9 1 -U1 10 -U2 19 -PU SAGE PUBLICATIONS LTD -PI LONDON -PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND -SN 2055-2076 -J9 DIGIT HEALTH -JI Digit. Health -PY 2024 -VL 10 -AR 20552076241279238 -DI 10.1177/20552076241279238 -PG 14 -WC Health Care Sciences & Services; Health Policy & Services; Public, - Environmental & Occupational Health; Medical Informatics -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Health Care Sciences & Services; Public, Environmental & Occupational - Health; Medical Informatics -GA F3F7N -UT WOS:001308721400001 -PM 39257873 -OA gold -DA 2025-07-11 -ER - -PT J -AU Linnenluecke, MK - Marrone, M - Singh, AK -AF Linnenluecke, Martina K. - Marrone, Mauricio - Singh, Abhay K. -TI Conducting systematic literature reviews and bibliometric analyses -SO AUSTRALIAN JOURNAL OF MANAGEMENT -LA English -DT Article -DE Bibliographic mapping; citation graph; entity linking; HistCite; R; - Bibliometrix; ResGap; science mapping; systematic literature review; - text mining -ID SCHOLARLY NETWORKS; HUMAN DIMENSIONS; MANAGEMENT; KNOWLEDGE; - VULNERABILITY; ADAPTATION; RESILIENCE; INNOVATION; TOPICS -AB Literature reviews play an essential role in academic research to gather existing knowledge and to examine the state of a field. However, researchers in business, management and related disciplines continue to rely on cursory and narrative reviews that lack a systematic investigation of the literature. This article details methodological steps for conducting literature reviews in a replicable and scientific fashion. This article also discusses bibliographic mapping approaches to visualise bibliometric information and findings from a systematic literature review. We hope that the insights provided in this article are useful for researchers at different stages of their careers - ranging from doctoral students who wish to assemble a broad overview of their field of interest to guide their work, to senior researchers who wish to publish authoritative literature reviews. - JEL Classification: C18, C80, C88, M10, M20 -C1 [Linnenluecke, Martina K.] Macquarie Univ, Ctr Corp Sustainabil & Environm Finance, Macquarie Business Sch, Eastern Rd, Sydney, NSW 2109, Australia. - [Marrone, Mauricio] Macquarie Univ, Macquarie Business Sch, Dept Accounting & Corp Governance, Sydney, NSW, Australia. - [Singh, Abhay K.] Macquarie Univ, Macquarie Business Sch, Dept Appl Finance, Sydney, NSW, Australia. -C3 Macquarie University; Macquarie University; Macquarie University -RP Linnenluecke, MK (corresponding author), Macquarie Univ, Ctr Corp Sustainabil & Environm Finance, Macquarie Business Sch, Eastern Rd, Sydney, NSW 2109, Australia. -EM martina.linnenluecke@mq.edu.au -RI ; Linnenluecke, Martina/J-7237-2013; Singh, Abhay/AAG-9813-2021 -OI Marrone, Mauricio/0000-0003-3896-6049; Singh, Abhay/0000-0002-3783-6325; - Linnenluecke, Martina/0000-0001-7984-9717; -CR Adams RJ, 2017, INT J MANAG REV, V19, P432, DOI 10.1111/ijmr.12102 - Addor N, 2019, WATER RESOUR RES, V55, P378, DOI 10.1029/2018WR022958 - Akobeng AK, 2005, ARCH DIS CHILD, V90, P845, DOI 10.1136/adc.2004.058230 - [Anonymous], 2018, Web Application Framework for R. 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Manag. -PD MAY -PY 2020 -VL 45 -IS 2 -BP 175 -EP 194 -DI 10.1177/0312896219877678 -PG 20 -WC Business; Management -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA LN1XT -UT WOS:000532739000001 -HC Y -HP N -DA 2025-07-11 -ER - -PT J -AU Kumar, V - Patel, S - Sharma, S - Kumar, R - Kaur, R -AF Kumar, Vishal - Patel, Sandeep - Sharma, Siddhartha - Kumar, Ritesh - Kaur, Rishemjit -TI Fifty Years of Cervical Myelopathy Research: Results from a Bibliometric - Analysis -SO ASIAN SPINE JOURNAL -LA English -DT Review -DE Bibliometrics; Cervical spondylotic myelopathy; Conceptual structure; - Performance mapping; Science mapping -ID SUPPLY CHAIN MANAGEMENT; SPONDYLOTIC MYELOPATHY; CONCEPTUAL STRUCTURE; - SURGICAL TECHNIQUES; DISC ARTHROPLASTY; GOOGLE-SCHOLAR; FUSION; SPINE; - SCIENCE; RADICULOPATHY -AB We performed bibliometric analysis of the research papers published on clinical cervical spondylotic myelopathy (CSM) in the last 50 years. We extracted bibliometric data from Scopus and PubMed from 1970 to 2020 pertaining to clinical studies of CSM. The pre-dominant journals, top cited articles, authors, and countries were identified using performance analysis. Science mapping was also performed to reveal the emerging trends, and conceptual and social structures of the authors and countries. Bibliometrix R-package was deployed for the study. The total numbers of clinical studies available in PubMed and Scopus were 1,302 and 3,470, respectively. The most cited article was published by Hilibrand AS, as observed in Scopus. Regarding the conceptual structure of the research, two main research themes were identified, one involving symptomatology, scientific-scale-based objective evaluation of symptoms, and surgical removal of the offending culprit, while the other was based on patho-etiology, relevant diagnostic modalities, and the surgery commonly performed for CSM. In terms of emerging trends, in recent times there is an increasing trend of scale-based objective evaluations, along with investigations of advanced nonoperative management. The United States is the most productive country, whereas Canada tops the list for inter-country collaboration. 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Yu JY, 2020, FUTURE INTERNET, V12, DOI 10.3390/fi12050091 -NR 45 -TC 3 -Z9 3 -U1 0 -U2 11 -PU KOREAN SOC SPINE SURGERY -PI SEOUL -PA DEPT ORTHOPAEDIC SURGERY, YONSEI UNIV, COLL MEDICINE, SEOUL, 120-752, - SOUTH KOREA -SN 1976-1902 -EI 1976-7846 -J9 ASIAN SPINE J -JI Asian Spine J. -PD DEC -PY 2022 -VL 16 -IS 6 -BP 983 -EP 994 -DI 10.31616/asj.2021.0239 -EA JAN 2022 -PG 12 -WC Orthopedics -WE Emerging Sources Citation Index (ESCI) -SC Orthopedics -GA DJ0D0 -UT WOS:000755033700001 -PM 35065547 -OA gold, Green Published -DA 2025-07-11 -ER - -PT J -AU Kum, G - Berglund, O - Hollander, J -AF Kum, Gina - Berglund, Olof - Hollander, Johan -TI Lost in definition: unravelling microplastics from marine coatings - through bibliometrics science mapping in thematic analysis and - systematic narrative literature review -SO ENVIRONMENTAL SCIENCES EUROPE -LA English -DT Article -DE Antifouling paint; Classification; Definition; Marine coatings; - Microplastics; Shipping -ID ACCUMULATION; SIZE; TOOL -AB Marine coatings used on merchant ships have recently emerged as a source of microplastics in marine environments. Marine coatings encompass all paints and coatings applied to various parts of a ship, primarily for anti-corrosion, antifouling anti-skid, heat-resistance, and cosmetic enhancement. However, marine coatings on merchant ships have evaded classification and were not included in the microplastic literature until recently. The purpose of this study is to examine the current state of the absence of a unified definition on a global scale, identify the factors that contribute to the exclusion of marine coatings under the microplastic classification and to analyse the thematic mapping and evolution of the keywords "definition", "classification", and "paint" or "marine coatings" in the field of microplastics. We conducted science mapping analysis using Bibliometrix software to examine 1078 papers and carried out a systematic narrative literature review to examine the current state of a standardised definition of microplastics and whether the absence of such impedes a unified interpretation and study of microplastics from marine coatings. Based on the science mapping analysis, this research indicates that "definition" and "paint" have become important keywords in the domain of microplastic research lately, playing a vital role in structuring the field. Meanwhile, the systematic narrative literature review unveiled that the absence of a standardised definition remains a subject of considerable debate, resulting in marine coatings evading classification as microplastics. With this study, we aim to advocate for the establishment of more precise guidelines and policies pertaining to microplastic pollution in marine environments and to promote the adoption of a unified approach towards the definition and classification of microplastics for the purposes of legislation and research. This will also path the way for the collection of better data on microplastic emissions from marine coatings, thereby closing the knowledge gap in this area. -C1 [Kum, Gina] World Maritime Univ, S-21118 Malmo, Sweden. - [Berglund, Olof] Lund Univ, Dept Biol, S-22100 Lund, Sweden. - [Hollander, Johan] World Maritime Univ, Ocean Sustainabil Governance & Management Unit, S-21118 Malmo, Sweden. -C3 Lund University -RP Kum, G (corresponding author), World Maritime Univ, S-21118 Malmo, Sweden.; Berglund, O (corresponding author), Lund Univ, Dept Biol, S-22100 Lund, Sweden. -EM w1011666@wmu.se; olof.berglund@biol.lu.se -FU Hempel; Nippon Foundation of Japan -FX GK acknowledges financial support received from Hempel. Whilst Hempel - provided funding for G.K.'s doctoral studies, this support did not - influence the study's design, data collection, analysis, interpretation, - or reporting. This research was conducted independently to maintain - scientific integrity and objectivity. 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To explore the development trend and fundamental characteristics of big data in entrepreneurship (BDIE) research, we conduct a comprehensive bibliometric analysis of BDIE based on 541 publications between 1993 and 2020 from Web of Science. On the one hand, this paper focuses on some essential characteristics of the BDIE publications, such as categories, citation, H-index, and the most cited publications. On the other hand, visual scientific maps are presented by bibliometric tools, i.e., Bibliometrix, VOS viewer, and CorTexT Manager, showing relationships between publications and knowledge structure in BDIE research. Finally, hot topics in current studies, knowledge, and limitations are discussed, guiding scholars to explore new research directions. This paper provides a relatively broad perspective for applying BDIE research, which contributes to understanding the evolution of BDIE research and inspires scholars in related fields. -C1 [Xiao, Anran; Qin, Yong; Xu, Zeshui] Sichuan Univ, Business Sch, Chengdu 610064, Peoples R China. - [Skare, Marinko] Juraj Dobrila Univ Pula, Fac Econ & Tourism Dr Mijo Mirkov, Preradoviceva 1-1, Pula 52100, Croatia. - [Skare, Marinko] Univ Econ & Human Sci, Warsaw, Poland. -C3 Sichuan University; University of Juraj Dobrila Pula -RP Xu, ZS (corresponding author), Sichuan Univ, Business Sch, Chengdu 610064, Peoples R China. -EM xiaoanran_ubby@163.com; yongqin_ahsc@163.com; xuzeshui@263.net; - mskare@unipu.hr -RI Xiao, Anran/LIC-9703-2024; Xu, Zeshui/N-8908-2013; Skare, - Marinko/L-5504-2019; Škare, Marinko/L-5504-2019 -OI Skare, Marinko/0000-0001-6426-3692; Xu, Zeshui/0000-0003-3547-2908; - Xiao, Anran/0000-0002-0638-2287 -FU National Natural Science Foundation of China [72071135] -FX Acknowledgement This study was funded by the National Natural Science - Foundation of China (No. 72071135) -CR Akpor-Robaro M.O.M., 2012, Management Science and Engineering, V6, P82, DOI [10.3968/j.mse.1913035X20120604.3620, DOI 10.3968/J.MSE.1913035X20120604.3620] - Alsadi AK, 2021, INT J INF SYST SUPPL, V14, P88, DOI 10.4018/IJISSCM.2021040105 - Ambos TC, 2022, J MANAGE STUD, V59, P92, DOI 10.1111/joms.12738 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Artz J. 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Ekon. -PY 2023 -VL 34 -IS 2 -BP 175 -EP 192 -DI 10.5755/j01.ee.34.2.30643 -PG 18 -WC Economics -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA H1YP5 -UT WOS:000993994500004 -OA gold -DA 2025-07-11 -ER - -PT J -AU Bastam, MN - Yazid, MRM - Borhan, MN -AF Bastam, Mukhlis Nahriri - Yazid, Muhamad Razuhanafi Mat - Borhan, Muhamad Nazri -TI School Travel Behavior Research Milestone (1979-2021): A Bibliometric - Review Analysis -SO INTERNATIONAL TRANSACTION JOURNAL OF ENGINEERING MANAGEMENT & APPLIED - SCIENCES & TECHNOLOGIES -LA English -DT Review -DE School travel; Mode choice; Bibliometric; science mapping; PRISMA - bibliometric analysis; Publication trend; Citation trend; Research trend -ID MODE CHOICE; URBAN FORM; OBESITY PREVENTION; CHILDREN; DISTANCE; - WALKING; TRIP; TRANSPORTATION; PERSPECTIVES; BARRIERS -AB The expansion of automobiles in the field of transport has fundamentally changed the travel patterns of mankind throughout the world. Disruption in the rhythm likewise impacts school travel, floating concerns of transportation, and child issues. This article aims to map and cluster current knowledge concerning school travel behavior topics by utilizing metadata from prior publications, using The Bibliometrix R-package instrument to perform bibliometric analysis on 513 metadata of scientific documents from Scopus and Web of Science databases between 1979 and 2021. The PRISMA criterion diagram is employed for the metadata searching and validating procedure. The study revealed a plethora of scientific documents and citations, particularly in the recent decade, and the countries from the western hemisphere continue to prime state-of-the-art research on this topic. Disciplinary: Transportation Engineering (Modelling, Behavior). (c) 2022 INT TRANS J ENG MANAG SCI TECH. -C1 [Bastam, Mukhlis Nahriri] Univ Kebangsaan Malaysia, Res Ctr, Fac Engn & Built Environm, Bangi, Malaysia. - [Yazid, Muhamad Razuhanafi Mat; Borhan, Muhamad Nazri] Univ Kebangsaan Malaysia, Smart & Sustainable Township Res Ctr, Fac Engn & Built Environm, Bangi, Malaysia. - [Bastam, Mukhlis Nahriri] Univ Bina Darma, Fac Engn, Dept Civil Engn, Palembang, Indonesia. -C3 Universiti Kebangsaan Malaysia; Universiti Kebangsaan Malaysia -RP Bastam, MN (corresponding author), Univ Kebangsaan Malaysia, Res Ctr, Fac Engn & Built Environm, Bangi, Malaysia.; Bastam, MN (corresponding author), Univ Bina Darma, Fac Engn, Dept Civil Engn, Palembang, Indonesia. -EM p91991@siswa.ukm.edu.my -RI Borhan, Muhamad/E-1035-2017; Bastam, Mukhlis Nahriri/AGT-9544-2022; - Yazid, Muhamad/AAJ-8887-2020 -OI Bastam, Mukhlis Nahriri/0000-0002-5820-292X -CR Agyeman S, 2020, TRANSPORT POLICY, V99, P63, DOI 10.1016/j.tranpol.2020.08.015 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Baslington H, 2010, EDUC 3-13, V38, P117, DOI 10.1080/03004270903099850 - Buliung RN, 2009, PREV MED, V48, P507, DOI 10.1016/j.ypmed.2009.03.001 - Cooper AR, 2005, AM J PREV MED, V29, P179, DOI 10.1016/j.amepre.2005.05.009 - Cooper AR, 2003, AM J PREV MED, V25, P273, DOI 10.1016/S0749-3797(03)00205-8 - Distefano N., 2019, Civil Eng. 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Trans. J. Eng. Manag. Appl. Sci. Technol. -PY 2022 -VL 13 -IS 5 -AR 13A5F -DI 10.14456/ITJEMAST.2022.90 -PG 16 -WC Multidisciplinary Sciences -WE Emerging Sources Citation Index (ESCI) -SC Science & Technology - Other Topics -GA 2U1WO -UT WOS:000822953200016 -DA 2025-07-11 -ER - -PT J -AU Padhan, L - Bhat, S -AF Padhan, Lakshmana - Bhat, Savita -TI Interrelationship between trade and environment: a bibliometric analysis - of published articles from the last two decades -SO ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH -LA English -DT Review -DE Bibliometric analysis; Trade; Environment; Performance analysis; - Bibliometrix; VOSViewer -ID FOREIGN DIRECT-INVESTMENT; POLLUTION HAVEN HYPOTHESIS; - INTERNATIONAL-TRADE; EMPIRICAL-ANALYSIS; SUPPLY CHAIN; POLICY; - PERFORMANCE; GREEN; LIBERALIZATION; CONSUMPTION -AB Extant literature indicates that the concepts of international trade and the environment are intertwined. There is a plethora of theoretical and empirical research studies that explore the relationship between the two concepts. However, no bibliometric attempts have been made to analyze these publications to understand the current research trends in the trade and environment regulation/protection/policy intersection. Hence, the present study conducted a bibliometric analysis of 1390 research articles collected from the Scopus database from 2000 to 2021. The study accomplished performance and science mapping analysis using Bibliometrix and VOSViewer software. The study shows an increasing publication trend. The most productive country was the USA (259 publications with 8400 citations), and the most productive institution was the University of California (33 publications). The study found that Cole MA was the most relevant author in this area by considering multiple matrices. By using keywords, conceptual structure, and bibliographic coupling analysis, the study suggests that future studies can be conducted on climate change, carbon leakage, climate policy, environmental protection, air pollution, economic growth, carbon dioxide emission, emission trading, abatement cost, environmental performance, green supply chain management, composition effect, carbon footprints, and multi-regional input-output model. The current study provides scholars and practitioners interested in trade and environmental interlinkages with a comprehensive overview of the domain by presenting readers with significant studies, authors, universities, concepts, and sources. Further, the study results will be helpful for scholars to get insights into the current research development trends and research themes in the trade and environmental regulation field. -C1 [Padhan, Lakshmana; Bhat, Savita] Natl Inst Technol Karnataka, Sch Humanities Social Sci & Management, NH 66,Srinivas Nagar, Mangalore 575025, Karnataka, India. -C3 National Institute of Technology (NIT System); National Institute of - Technology Karnataka -RP Padhan, L (corresponding author), Natl Inst Technol Karnataka, Sch Humanities Social Sci & Management, NH 66,Srinivas Nagar, Mangalore 575025, Karnataka, India. -EM lakshmana.207sm002@nitk.edu.in; savitapbhat@nitk.edu.in -RI Bhat, Savita/P-8987-2016; Padhan, Lakshmana/IWE-2729-2023 -OI Bhat, Savita/0000-0002-0426-4279; /0000-0002-5064-2517 -FU National Institute of Technology Karnataka, Surathkal, India -FX The authors wish to acknowledge the National Institute of Technology - Karnataka, Surathkal, India, for supporting the study. 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Sci. Pollut. Res. -PD FEB -PY 2023 -VL 30 -IS 7 -BP 17051 -EP 17075 -DI 10.1007/s11356-023-25168-5 -EA JAN 2023 -PG 25 -WC Environmental Sciences -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Environmental Sciences & Ecology -GA F7PY9 -UT WOS:000911910500006 -PM 36626051 -OA Green Submitted -DA 2025-07-11 -ER - -PT J -AU Di Cosmo, A - Pinelli, C - Scandurra, A - Aria, M - D'Aniello, B -AF Di Cosmo, Anna - Pinelli, Claudia - Scandurra, Anna - Aria, Massimo - D'Aniello, Biagio -TI Research Trends in Octopus Biological Studies -SO ANIMALS -LA English -DT Article -DE cephalopods; model species; bibliometrix; bibliometric analysis; science - mapping -ID VULGARIS; SCIENCE; TOOL -AB Simple Summary Octopuses represent model studies for different fields of scientific inquiry. We provide a bibliometric analysis on biological research trends in octopuses studies by using bibliometrix, a new and powerful R-tool. The analysis was executed from January 1985 to December 2020 including scientific products reported in Web of Science (WoS) database. The main results showed an increasing effort in research involving octopuses with a greater number of journals reporting research on these animals, as well as countries, institutions, and researchers involved. Some research themes lost importance over time, while some new themes appeared recently. Current data provide significant insight into the evolving trends in octopuses studies. Octopuses represent interesting model studies for different fields of scientific inquiry. The present study provides a bibliometric analysis on research trends in octopuses biological studies. The analysis was executed from January 1985 to December 2020 including scientific products reported in the Web of Science database. The period of study was split into two blocks ("earlier period" (EP): 1985-2010; "recent period" (RP): 2011-2020) to analyze the evolution of the research topics over time. All publications of interest were identified by using the following query: ((AK = octopus) OR (AB = octopus) OR (TI = octopus)). Data information was converted into an R-data frame using bibliometrix. Octopuses studies appeared in 360 different sources in EP, while they increased to 408 in RP. Sixty countries contributed to the octopuses studies in the EP, while they were 78 in the RP. The number of affiliations also increased between EP and RP, with 835 research centers involved in the EP and 1399 in the RP. In the EP 5 clusters (i.e., "growth and nutrition", "pollution impact", "morphology", "neurobiology", "biochemistry") were represented in a thematic map, according to their centrality and density ranking. In the RP the analysis identified 4 clusters (i.e., "growth and nutrition", "ecology", "pollution impact", "genes, behavior, and brain evolution"). The UK with Ireland, and the USA with Canada shared the highest number of publications in the EP, while in the RP, Spain and Portugal were the leading countries. The current data provide significant insight into the evolving trends in octopuses studies. -C1 [Di Cosmo, Anna; Scandurra, Anna; D'Aniello, Biagio] Univ Naples Federico II, Dept Biol, Via Cinthia, I-80126 Naples, Italy. - [Pinelli, Claudia] Univ Campania Luigi Vanvitelli, Dept Environm Biol & Pharmaceut Sci & Technol, I-81100 Caserta, Italy. - [Aria, Massimo] Univ Naples Federico II, Dept Econ & Stat, Via Cinthia, I-80126 Naples, Italy. -C3 University of Naples Federico II; Universita della Campania Vanvitelli; - University of Naples Federico II -RP Di Cosmo, A (corresponding author), Univ Naples Federico II, Dept Biol, Via Cinthia, I-80126 Naples, Italy. -EM anna.dicosmo@unina.it; claudia.pinelli@unicampania.it; - anna.scandurra@unina.it; massimo.aria@unina.it; biagio.daniello@unina.it -RI Pinelli, Claudia/AAF-3627-2019; Aria, Massimo/O-7983-2015; D'Aniello, - Biagio/N-5287-2019; Scandurra, Anna/AAC-2887-2020 -OI Aria, Massimo/0000-0002-8517-9411; Di Cosmo, Anna/0000-0002-1018-9957; - Scandurra, Anna/0000-0002-4442-2948; Pinelli, - Claudia/0000-0002-1845-9886; D'ANIELLO, BIAGIO/0000-0002-1176-946X -CR [Anonymous], 2013, MAPPING SCI FRONTIER - Aria M, 2021, ANIM COGN, V24, P541, DOI 10.1007/s10071-020-01448-2 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bertapelle C, 2017, J EXP ZOOL PART B, V328, P347, DOI 10.1002/jez.b.22735 - Cahlik T, 2000, SCIENTOMETRICS, V49, P373, DOI 10.1023/A:1010581421990 - CALLON M, 1991, SCIENTOMETRICS, V22, P155, DOI 10.1007/BF02019280 - Clark C., 2019, THESIS NOVA SE U FOR - Cobo MJ, 2015, KNOWL-BASED SYST, V80, P3, DOI 10.1016/j.knosys.2014.12.035 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - De Battisti F, 2013, STAT METHOD APPL-GER, V22, P269, DOI 10.1007/s10260-012-0217-0 - Di Cosmo A, 2018, FRONT PHYSIOL, V9, DOI 10.3389/fphys.2018.01050 - Di Cosmo A, 2018, RESULTS PROBL CELL D, V65, P585, DOI 10.1007/978-3-319-92486-1_26 - Doubleday ZA, 2016, CURR BIOL, V26, pR406, DOI 10.1016/j.cub.2016.04.002 - Egghe L, 2006, SCIENTOMETRICS, V69, P131, DOI 10.1007/s11192-006-0144-7 - Falagas ME, 2008, FASEB J, V22, P338, DOI 10.1096/fj.07-9492LSF - Fanelli D, 2016, PLOS ONE, V11, DOI 10.1371/journal.pone.0149504 - Halbach OVU, 2011, ANN ANAT, V193, P191, DOI 10.1016/j.aanat.2011.03.011 - Hirsch JE, 2005, P NATL ACAD SCI USA, V102, P16569, DOI 10.1073/pnas.0507655102 - Jereb P, 2014, OCTOPODS VAMPIRE SQU, V3 - Juárez OE, 2019, PLOS ONE, V14, DOI 10.1371/journal.pone.0216982 - Liberati A, 2009, BMJ-BRIT MED J, V339, DOI [10.1136/bmj.b2700, 10.1371/journal.pmed.1000097, 10.1186/2046-4053-4-1, 10.1136/bmj.i4086, 10.1136/bmj.b2535, 10.1016/j.ijsu.2010.07.299, 10.1016/j.ijsu.2010.02.007] - Maselli V, 2020, BIOLOGY-BASEL, V9, DOI 10.3390/biology9080196 - Maselli V, 2020, ANIMALS-BASEL, V10, DOI 10.3390/ani10030457 - Maselli V, 2018, FRONT PHYSIOL, V9, DOI 10.3389/fphys.2018.00220 - Moral-Muñoz JA, 2020, PROF INFORM, V29, DOI 10.3145/epi.2020.ene.03 - NARIN F, 1991, SERIALS LIBR, V21, P33, DOI 10.1300/J123v21n02_05 - Newman MEJ, 2001, PHYS REV E, V64, DOI 10.1103/PhysRevE.64.016131 - O'Brien CE, 2018, FRONT PHYSIOL, V9, DOI 10.3389/fphys.2018.00700 - OBrien CE., 2019, Encyclopedia of animal behavior, VSecond Edition, P142, DOI [10.1016/B978-0-12-809633-8.90074-8, DOI 10.1016/B978-0-12-809633-8.90074-8] - Persson O, 2004, SCIENTOMETRICS, V60, P421, DOI 10.1023/B:SCIE.0000034384.35498.7d - Villanueva R, 2017, FRONT PHYSIOL, V8, P1, DOI 10.3389/fphys.2017.00598 - Wallin JA, 2005, BASIC CLIN PHARMACOL, V97, P261, DOI 10.1111/j.1742-7843.2005.pto_139.x - Winlow W, 2019, FRONT PHYSIOL, V10, DOI 10.3389/fphys.2019.01141 - Winlow W, 2018, FRONT PHYSIOL, V9, DOI 10.3389/fphys.2018.01147 - Winters GC, 2020, J MORPHOL, V281, P790, DOI 10.1002/jmor.21141 - Zarrella I, 2015, CURR OPIN NEUROBIOL, V35, P74, DOI 10.1016/j.conb.2015.06.012 - Zhang J, 2016, J ASSOC INF SCI TECH, V67, P967, DOI 10.1002/asi.23437 -NR 37 -TC 29 -Z9 31 -U1 5 -U2 41 -PU MDPI -PI BASEL -PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND -SN 2076-2615 -J9 ANIMALS-BASEL -JI Animals -PD JUN -PY 2021 -VL 11 -IS 6 -AR 1808 -DI 10.3390/ani11061808 -PG 15 -WC Agriculture, Dairy & Animal Science; Veterinary Sciences; Zoology -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Agriculture; Veterinary Sciences; Zoology -GA TB3YM -UT WOS:000667882700001 -PM 34204419 -OA gold, Green Published -DA 2025-07-11 -ER - -PT J -AU Gahane, V - Deshpande, Y -AF Gahane, Varsha - Deshpande, Yogesh -TI Gynecological Cancer Research in India: A Bibliometric Analysis -SO INDIAN JOURNAL OF SURGERY -LA English -DT Review -DE Gynecological cancer; Bibliometric analysis; Web of Science; Performance - analysis; Science mapping; India -ID SCIENCE -AB Gynecological cancer originating in the female reproductive tract is one of the most common cancers among women, and its incidence is increasing every year in India. This results in high mortality, poor survival outcomes, and psychological effects. Several theoretical and empirical investigations examined gynecological cancer and its varied influences. However, no bibliometric attempts were performed to screen these publications to comprehend the most recent developments and trends in gynecological cancer research in India. Thus, this study aimed to examine the recent development of gynecological cancer research using bibliometric analysis of 3378 research articles collected from the Web of Science database from 2003 to 2022. The study used the Bibliometrix and VOSviewer software to inspect the performance and the science mapping analysis. The performance analysis findings indicate an increase in publication trends after 2008 in India. In scientific production, India collaborated with 116 countries worldwide. The most productive journal, author, and institution are Plos One, Rengaswamy Sankaranarayanan, and All India Institute of Medical Sciences, respectively. By using keywords, intellectual structure, and conceptual structure, the analysis indicates that future studies could focus on cervical carcinoma, ovarian cancer, human papillomavirus, and epithelial ovarian cancer. In light of the overall findings, it is recommended that academicians and practitioners interested in gynecological cancer-based research deliver an overview of the field by providing readers with essential papers, authors, universities, concepts, and sources. These outcomes will also help scholars in gaining a better understanding of current developments, trends, and issues in gynecological cancer research. -C1 [Gahane, Varsha; Deshpande, Yogesh] Visvesvaraya Natl Inst Technol, Dept Humanities & Social Sci, Nagpur 440010, India. -C3 National Institute of Technology (NIT System); Visvesvaraya National - Institute of Technology, Nagpur -RP Gahane, V (corresponding author), Visvesvaraya Natl Inst Technol, Dept Humanities & Social Sci, Nagpur 440010, India. -EM varshagahane02@gmail.com; drymdeshpande@gmail.com -RI Gahane, Varsha/LKO-4264-2024 -OI Gahane, Varsha Hemraj/0000-0002-0475-5668 -CR Ahmad S, 2021, SAGE OPEN, V11, DOI 10.1177/21582440211046934 - Anaya-Ruiz M, 2014, ASIAN PAC J CANCER P, V15, P8689, DOI 10.7314/APJCP.2014.15.20.8689 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bretas VPG, 2021, J BUS RES, V133, P51, DOI 10.1016/j.jbusres.2021.04.067 - Chen XY, 2020, TRANSPORT POLICY, V85, P1, DOI 10.1016/j.tranpol.2019.10.004 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - Crane K, 2010, J NATL CANCER I, V102, P1613, DOI 10.1093/jnci/djq445 - Di Tucci C, 2022, CANCERS, V14, DOI 10.3390/cancers14102500 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - El Bairi K, 2021, GYNECOL ONCOL REP, V37, DOI 10.1016/j.gore.2021.100777 - Elango B, 2019, J ENTREP, V28, P223, DOI 10.1177/0971355719851897 - Forliano C, 2021, TECHNOL FORECAST SOC, V165, DOI 10.1016/j.techfore.2020.120522 - FREEMAN LC, 1979, SOC NETWORKS, V1, P215, DOI 10.1016/0378-8733(78)90021-7 - Globocan, 2020, WORLD HLTH ORG WHO G - Gyanendra Yumnam, 2022, Arabian Journal of Geosciences, DOI 10.1007/s12517-022-10707-0 - Hirsch JE, 2007, P NATL ACAD SCI USA, V104, P19193, DOI 10.1073/pnas.0707962104 - Huang Yue, 2021, International Journal of Crowd Science, V5, DOI 10.1108/IJCS-01-2021-0001 - Huang YY, 2023, CLIN EXP MED, V23, P175, DOI 10.1007/s10238-022-00800-9 - Jemal Ahmedin, 2011, CA Cancer J Clin, V61, P69, DOI 10.3322/caac.20107 - Jones GL, 2006, AM J OBSTET GYNECOL, V194, P26, DOI 10.1016/j.ajog.2005.04.060 - Kang Q, 2021, KNOWL MAN RES PRACT, V19, P8, DOI 10.1080/14778238.2019.1701964 - Khanra S, 2021, TOUR MANAG PERSPECT, V37, DOI 10.1016/j.tmp.2020.100777 - Koseoglu MA, 2016, BRQ-BUS RES Q, V19, P153, DOI 10.1016/j.brq.2016.02.001 - Liu JJ, 2020, TECHNOL FORECAST SOC, V155, DOI 10.1016/j.techfore.2020.120022 - Mukherjee D, 2022, J BUS RES, V145, P864, DOI 10.1016/j.jbusres.2022.03.011 - Nayak S, 2023, INT J HEALTHCARE MAN, V16, P188, DOI 10.1080/20479700.2022.2085848 - Panes P, 2022, CLEAN ENG TECHNOL, V8, DOI 10.1016/j.clet.2022.100468 - PRITCHARD A, 1969, J DOC, V25, P348 - pubmed.ncbi.nlm.nih.gov, MAPPING TRENDS HOTSP - Raju NV, 2020, DIABETES METAB SYND, V14, P1171, DOI 10.1016/j.dsx.2020.07.007 - Secinaro S, 2020, J CLEAN PROD, V264, DOI 10.1016/j.jclepro.2020.121503 - Shoaib M, 2023, ENVIRON SCI POLLUT R, V30, P14029, DOI 10.1007/s11356-022-24844-2 - Tandon A, 2021, TECHNOL FORECAST SOC, V166, DOI 10.1016/j.techfore.2021.120649 - van Eck N. J., 2020, Leiden: Univeristeit Leiden - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Wang NX, 2016, DECIS SUPPORT SYST, V86, P35, DOI 10.1016/j.dss.2016.03.006 - Wenzel L, 2003, CLIN THER, V25, pD26, DOI 10.1016/S0149-2918(03)80262-X - Who, 2021, WHO CANC TODAY ESTIM - Xue XL, 2018, NAT HAZARDS, V90, P477, DOI 10.1007/s11069-017-3040-y - Yang ZL, 2021, INT J INTELL SYST, V36, P6387, DOI 10.1002/int.22554 - Zhang DY, 2019, FINANC RES LETT, V29, P425, DOI 10.1016/j.frl.2019.02.003 - Zhang JM, 2023, FRONT ONCOL, V13, DOI 10.3389/fonc.2023.1082423 - Zhao JY, 2023, FRONT ONCOL, V13, DOI 10.3389/fonc.2023.1115852 -NR 43 -TC 1 -Z9 1 -U1 1 -U2 5 -PU SPRINGER INDIA -PI NEW DELHI -PA 7TH FLOOR, VIJAYA BUILDING, 17, BARAKHAMBA ROAD, NEW DELHI, 110 001, - INDIA -SN 0972-2068 -EI 0973-9793 -J9 INDIAN J SURG -JI Indian J. Surg -PD APR -PY 2025 -VL 87 -IS 2 -BP 253 -EP 266 -DI 10.1007/s12262-024-04132-8 -EA AUG 2024 -PG 14 -WC Surgery -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Surgery -GA 1FD2U -UT WOS:001296514900001 -DA 2025-07-11 -ER - -PT J -AU Maharani, IAK - Usman, I -AF Maharani, Ida Ayu Kartika - Usman, Indrianawati -TI The First 17 Years of the Journal of Management, Spirituality, and - Religion (JMSR): Bibliometric Overview -SO JOURNAL OF MANAGEMENT SPIRITUALITY & RELIGION -LA English -DT Article -DE Bibliometric; science mapping; VOSViewer; Bibliometrix; performance - analysis; JMSR -ID WORKPLACE SPIRITUALITY; WORK; MODEL; FOUNDATIONS; PERFORMANCE; - LEADERSHIP; BEHAVIOR; VALUES; TOOL -AB The Journal of Management, Spirituality, and Religion (JMSR) has been a leading scientific source for scholars interested in the religious and spiritual aspects of managing human capital in organizations. It was created to connect the concepts of spirituality and religiosity to increase awareness of people's spirituality and spiritual leadership in a business setting. It was also, to comprehend the effects of pluralism on organizations as a whole and the critical and distinct role of the various religious views held and the spirituality of each individual. This study uses bibliometric analysis techniques to retrieve all publications from the Scopus database from 2004 to 2020 to honor the 17 years of the JMSR's journey. The current study was carried out to IP: 203.8.109 20 On: Fri, 07 Jul 20 highlight the JMSR's growth, development, and intellectual structure in terms of impact, citations, theme, topic trend evolution, most contributing universities, and collaboration network. Delivered by Ingenta -C1 [Maharani, Ida Ayu Kartika; Usman, Indrianawati] Univ Airlangga, Surabaya, Indonesia. -C3 Airlangga University -RP Maharani, IAK (corresponding author), Univ Airlangga, Surabaya, Indonesia. -EM ida.ayu.kartika.m-2020@feb.unair.ac.id -RI Usman, Indrianawati/GQR-2148-2022; Maharani, Ida Ayu - Kartika/HKV-7841-2023 -OI Maharani, Ida Ayu Kartika/0000-0002-5809-7883 -CR Afsar B, 2015, J MANAG SPIRITUAL RE, V12, P329, DOI 10.1080/14766086.2015.1060515 - Agarwala R, 2019, J MANAG SPIRITUAL RE, V16, P32, DOI 10.1080/14766086.2018.1495098 - Aksnes DW, 2019, J DATA INFO SCI, V4, P1, DOI 10.2478/jdis-2019-0001 - Aksnes DW, 2019, SAGE OPEN, V9, DOI 10.1177/2158244019829575 - [Anonymous], 2016, J MANAG SPIRITUAL RE, DOI DOI 10.1080/14766086.2016.1185292 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Arnetz BB, 2013, J MANAG SPIRITUAL RE, V10, P271, DOI 10.1080/14766086.2013.801027 - Balog AM, 2014, J MANAG SPIRITUAL RE, V11, P159, DOI 10.1080/14766086.2013.836127 - Bihari A, 2023, J INF SCI, V49, P624, DOI 10.1177/01655515211014478 - Bolton SC, 2010, J MANAG SPIRITUAL RE, V7, P157, DOI 10.1080/14766081003746422 - Bright DS, 2006, J MANAG SPIRITUAL RE, V3, P78, DOI 10.1080/14766080609518612 - BROADUS RN, 1987, SCIENTOMETRICS, V12, P373, DOI 10.1007/BF02016680 - Brown RB, 2003, ORGANIZATION, V10, P393, DOI 10.1177/1350508403010002013 - CALLON M, 1991, SCIENTOMETRICS, V22, P155, DOI 10.1007/BF02019280 - Chaston J, 2015, J MANAG SPIRITUAL RE, V12, P111, DOI 10.1080/14766086.2014.938244 - Cobo MJ, 2011, J AM SOC INF SCI TEC, V62, P1382, DOI 10.1002/asi.21525 - Collins D, 2010, J MANAG SPIRITUAL RE, V7, P95, DOI 10.1080/14766081003746414 - Driscoll C, 2019, J MANAG SPIRITUAL RE, V16, P155, DOI 10.1080/14766086.2019.1570474 - Driver M, 2007, J MANAG SPIRITUAL RE, V4, P56, DOI 10.1080/14766080709518646 - Exline JJ, 2011, J MANAG SPIRITUAL RE, V8, P123, DOI 10.1080/14766086.2011.581812 - Fang HQ, 2013, J MANAG SPIRITUAL RE, V10, P253, DOI 10.1080/14766086.2012.758055 - Fornaciari CJ, 2009, J MANAG SPIRITUAL RE, V6, P301, DOI 10.1080/14766080903290085 - Fry LW, 2017, J MANAG SPIRITUAL RE, V14, P22, DOI 10.1080/14766086.2016.1202130 - Fry LW, 2010, J MANAG SPIRITUAL RE, V7, P283, DOI 10.1080/14766086.2010.524983 - Geh E, 2009, J MANAG SPIRITUAL RE, V6, P287, DOI 10.1080/14766080903290093 - Gingras Y., 2016, BIBLIOMETRICS RES EV - Godwin JL, 2016, J MANAG SPIRITUAL RE, V13, P64, DOI 10.1080/14766086.2015.1122546 - Gotsis G, 2008, J BUS ETHICS, V78, P575, DOI 10.1007/s10551-007-9369-5 - Guerrero-Bote Vicente P, 2020, Front Res Metr Anal, V5, P593494, DOI 10.3389/frma.2020.593494 - Hirsch JE, 2005, P NATL ACAD SCI USA, V102, P16569, DOI 10.1073/pnas.0507655102 - Hunsaker WD, 2016, J MANAG SPIRITUAL RE, V13, P206, DOI 10.1080/14766086.2016.1159974 - Jamali D, 2013, J MANAG SPIRITUAL RE, V10, P309, DOI 10.1080/14766086.2013.802251 - Jonsen RH, 2016, J MANAG SPIRITUAL RE, V13, P288, DOI 10.1080/14766086.2016.1172250 - Kauanui SK, 2008, J MANAG SPIRITUAL RE, V5, P160, DOI 10.1080/14766080809518698 - KESSLER MM, 1963, AM DOC, V14, P10, DOI 10.1002/asi.5090140103 - Khari C, 2020, J MANAG SPIRITUAL RE, V17, P352, DOI 10.1080/14766086.2020.1774916 - King JE, 2005, J MANAG SPIRITUAL RE, V2, P173, DOI 10.1080/14766080509518579 - Lee S, 2014, J MANAG SPIRITUAL RE, V11, P45, DOI 10.1080/14766086.2013.801023 - Low A, 2012, J MANAG SPIRITUAL RE, V9, P335, DOI 10.1080/14766086.2012.744543 - Lu K, 2012, J AM SOC INF SCI TEC, V63, P1973, DOI 10.1002/asi.22628 - Madison K, 2013, J MANAG SPIRITUAL RE, V10, P160, DOI 10.1080/14766086.2012.758052 - Martin A., 2019, IMPACT SOCIAL SCI BL, P1 - Molloy KA, 2019, J MANAG SPIRITUAL RE, V16, P428, DOI 10.1080/14766086.2019.1657489 - Naimon EC, 2013, J MANAG SPIRITUAL RE, V10, P91, DOI 10.1080/14766086.2012.758049 - Petchsawang P, 2012, J MANAG SPIRITUAL RE, V9, P189, DOI 10.1080/14766086.2012.688623 - Phipps KA, 2019, J MANAG SPIRITUAL RE, V16, P339, DOI 10.1080/14766086.2019.1602074 - PRITCHARD A, 1969, J DOC, V25, P348 - Ritchie M., 1978, LIT BIBLIOMETRICS - Saks AM, 2011, J MANAG SPIRITUAL RE, V8, P317, DOI 10.1080/14766086.2011.630170 - Singh RK, 2022, MANAGE DECIS, V60, P1296, DOI 10.1108/MD-11-2020-1466 - Tackney CT, 2017, J MANAG SPIRITUAL RE, V14, P245, DOI 10.1080/14766086.2017.1316764 - van den Dool EC, 2012, J MANAG SPIRITUAL RE, V9, P49, DOI 10.1080/14766086.2012.641097 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Van Noorden R., 2014, Nature, DOI DOI 10.1038/NATURE.2014.16269 - Vu MC, 2018, J MANAG SPIRITUAL RE, V15, P155, DOI 10.1080/14766086.2017.1410491 - Weitz E, 2012, J MANAG SPIRITUAL RE, V9, P255, DOI 10.1080/14766086.2012.730782 -NR 56 -TC 3 -Z9 3 -U1 0 -U2 8 -PU IMASR-INT ASSOC MANAGEMENT SPIRITUALITY & RELIGION -PI LONDON -PA 262 SHAKESPEARE TOWER, LONDON, ENGLAND -SN 1476-6086 -EI 1942-258X -J9 J MANAG SPIRITUAL RE -JI J. Manag. Spiritual. Relig. -PD JUN -PY 2023 -VL 20 -IS 3 -BP 206 -EP 229 -DI 10.51327/LWUW8903 -PG 24 -WC Religion -WE Emerging Sources Citation Index (ESCI) -SC Religion -GA L9IB2 -UT WOS:001026316900001 -DA 2025-07-11 -ER - -PT J -AU Xu, D - Xu, ZS -AF Xu, Duo - Xu, Zeshui -TI Bibliometric analysis of decision-making in healthcare management from - 1998 to 2021 -SO INTERNATIONAL JOURNAL OF HEALTHCARE MANAGEMENT -LA English -DT Article -DE Bibliometric analysis; decision making; healthcare management -ID CITATION; PATTERNS; SCIENCE -AB Healthcare management (HCM) has attracted significant attention from scholars and practitioners, and decision-making (DM) is always perceived as a crucial managerial function. This paper attempts to explore the trend and structure of DM research in the field of HCM (DM-HCM) by conducting a bibliometric analysis of publications from 1998 to 2021. A total of 581 documents covering all the available evidence are retrieved from the Web of Science (WoS) core collection. First, a descriptive performance analysis is performed based on widely accepted bibliometric indicators, followed by identifying primary contributors in the research community. Then, a science mapping analysis is implemented to discover the structural connections among different research constituents using three visualization tools, namely, VoS viewer, CiteSpace, and Bibliometrix. The citation-related and co-authorship networks are analyzed to explore the intellectual structure of the bibliometric corpus. Moreover, the keyword co-occurrence, timeline view, and evolution analysis enrich the understanding of thematic clusters and identify the DM-HCM research focus. Finally, the main findings are summarized, and possible research directions are proposed. -C1 [Xu, Duo] Stevens Inst Technol, Business Sch, Hoboken, NJ 07030 USA. - [Xu, Zeshui] Sichuan Univ, Business Sch, 24 South Sect 1 Yihuan Rd, Chengdu 610064, Peoples R China. -C3 Stevens Institute of Technology; Sichuan University -RP Xu, ZS (corresponding author), Sichuan Univ, Business Sch, 24 South Sect 1 Yihuan Rd, Chengdu 610064, Peoples R China. -EM xuzeshui@263.net -RI ; Xu, Zeshui/N-8908-2013 -OI Xu, Zeshui/0000-0003-3547-2908; -CR Abdel-Basset M, 2019, J MED SYST, V43, DOI 10.1007/s10916-019-1156-1 - Akmal A, 2020, HEALTH POLICY, V124, P615, DOI 10.1016/j.healthpol.2020.04.008 - Alsalem MA, 2022, ARTIF INTELL REV, V55, P4979, DOI 10.1007/s10462-021-10124-x - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Asan O, 2020, J MED INTERNET RES, V22, DOI 10.2196/15154 - Basile LJ, 2023, TECHNOVATION, V120, DOI 10.1016/j.technovation.2022.102482 - Boyack KW, 2010, J AM SOC INF SCI TEC, V61, P2389, DOI 10.1002/asi.21419 - Buchbinder S B., 2019, Introduction to health care management - Chen CM, 2006, J AM SOC INF SCI TEC, V57, P359, DOI 10.1002/asi.20317 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Ellis LA, 2019, SAFETY SCI, V118, P241, DOI 10.1016/j.ssci.2019.04.044 - Fusco F, 2020, BMC HEALTH SERV RES, V20, DOI 10.1186/s12913-020-05241-2 - Galetsi P, 2020, INT J INFORM MANAGE, V50, P206, DOI 10.1016/j.ijinfomgt.2019.05.003 - Guo YQ, 2020, J MED INTERNET RES, V22, DOI 10.2196/18228 - Zolfani SH, 2020, SYMMETRY-BASEL, V12, DOI 10.3390/sym12060886 - Hirsch JE, 2005, P NATL ACAD SCI USA, V102, P16569, DOI 10.1073/pnas.0507655102 - Li Y, 2020, INT J MACH LEARN CYB, V11, P2807, DOI 10.1007/s13042-020-01152-0 - Lu CC, 2019, FRONT PUBLIC HEALTH, V7, DOI 10.3389/fpubh.2019.00384 - Ma N, 2008, INFORM PROCESS MANAG, V44, P800, DOI 10.1016/j.ipm.2007.06.006 - Martín-Martín A, 2018, J INFORMETR, V12, P1160, DOI 10.1016/j.joi.2018.09.002 - Morgan O, 2019, PHILOS T R SOC B, V374, DOI 10.1098/rstb.2018.0365 - Nayak S, 2023, INT J HEALTHCARE MAN, V16, P188, DOI 10.1080/20479700.2022.2085848 - Punnakitikashem P, 2020, SUSTAINABILITY-BASEL, V12, DOI 10.3390/su12010205 - Saggi MK, 2018, INFORM PROCESS MANAG, V54, P758, DOI 10.1016/j.ipm.2018.01.010 - Singh VK, 2021, SCIENTOMETRICS, V126, P5113, DOI 10.1007/s11192-021-03948-5 - Tahamtan Iman, 2016, Scientometrics, V107, P1195, DOI 10.1007/s11192-016-1889-2 - Thompson JM, 2010, J PUBLIC HEALTH MAN, V16, P167, DOI 10.1097/PHH.0b013e3181c8cb51 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Wang XX, 2022, FUZZY OPTIM DECIS MA, V21, P649, DOI 10.1007/s10700-021-09380-x - Wang XX, 2021, INFORM SCIENCES, V547, P328, DOI 10.1016/j.ins.2020.08.036 - Wong AKF, 2021, J HOSP TOUR MANAG, V49, P270, DOI 10.1016/j.jhtm.2021.09.015 - Ye N, 2020, J CLEAN PROD, V272, DOI 10.1016/j.jclepro.2020.122679 -NR 32 -TC 2 -Z9 2 -U1 1 -U2 26 -PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD -PI ABINGDON -PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND -SN 2047-9700 -EI 2047-9719 -J9 INT J HEALTHCARE MAN -JI Int. J. Healthcare Manag. -PD OCT 2 -PY 2023 -VL 16 -IS 4 -BP 623 -EP 637 -DI 10.1080/20479700.2022.2134641 -EA OCT 2022 -PG 15 -WC Health Policy & Services -WE Emerging Sources Citation Index (ESCI) -SC Health Care Sciences & Services -GA U0FK6 -UT WOS:000868215700001 -DA 2025-07-11 -ER - -PT J -AU Voutsa, MC -AF Voutsa, Maria C. -TI Disparaging humorous advertising: A bibliometric review -SO JOURNAL OF MARKETING COMMUNICATIONS -LA English -DT Review; Early Access -DE Disparagement humor; comedic violence; parody; satire; benign violation; - humor -ID COMEDIC-VIOLENCE; MODERATING ROLE; UNITED-STATES; IMPACT; RESPONSES; - BRAND; ADVERTISEMENTS; AGGRESSION; CONSUMERS; PARODIES -AB The proliferation of disparaging humorous advertising (DHA) has garnered significant interest among researchers due to its dual potential to engage and offend audiences. Its potential to alienate audience segments underscores the importance of understanding its nuanced effects, particularly regarding cultural sensitivity and ethical considerations. Academic research is critical in identifying the conditions under which DHA is effective, focusing on audience demographics, cultural context, and the specific nature of the humor used. This bibliometric review encompasses 63 published articles spanning 34 years, sourced from the Scopus database. Performance analysis (via the Bibliometrix package in R) and science mapping (using VOSviewer software for visualization), including citation and co-authorship analysis and bibliographic coupling, are used to reveal and discuss seven discrete thematic areas: (1) Cross-cultural, (2) Perceived Humorousness, (3) Sharing Intention, (4) Level of Disparagement, (5) Target Audience, (6) Gender Portrayals, and (7) Parody & Satire. 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Market. Commun. -PD 2024 SEP 7 -PY 2024 -DI 10.1080/13527266.2024.2397648 -EA SEP 2024 -PG 25 -WC Business; Communication -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics; Communication -GA E9N4N -UT WOS:001306192600001 -DA 2025-07-11 -ER - -PT J -AU Michailidis, PD -AF Michailidis, Panagiotis D. -TI A Scientometric Study of the Stylometric Research Field -SO INFORMATICS-BASEL -LA English -DT Article -DE bibliometric analysis; stylometry; biblioshiny; Scopus -ID AUTHORSHIP ATTRIBUTION; IDENTIFICATION -AB Stylometry has gained great popularity in digital humanities and social sciences. Many works on stylometry have recently been reported. However, there is a research gap regarding review studies in this field from a bibliometric and evolutionary perspective. Therefore, in this paper, a bibliometric analysis of publications from the Scopus database in the stylometric research field was proposed. Then, research articles published between 1968 and 2021 were collected and analyzed using the Bibliometrix R package for bibliometric analysis via the Biblioshiny web interface. Empirical results were also presented in terms of the performance analysis and the science mapping analysis. From these results, it is concluded that there has been a strong growth in stylometry research in recent years, while the USA, Poland, and the UK are the most productive countries, and this is due to many strong research partnerships. 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S. - Coelho, Ronaldo C. - Muniz, Edvani C. - Barbosa, Herbert de S. -TI Optimization of pectin extraction using response surface methodology: A - bibliometric analysis -SO CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS -LA English -DT Article -DE Pectin; Optimization; Bibliometric; Co-citation; Optimization of methods - for pectin; Extraction -ID MICROWAVE-ASSISTED EXTRACTION; SOUR ORANGE PEEL; CITRIC-ACID; - BOX-BEHNKEN; SEQUENTIAL EXTRACTION; ENRICHED MATERIALS; APPLE POMACE; - BY-PRODUCT; ULTRASOUND; WASTE -AB In this study, 209 articles have been surveyed on the "Pectin Extraction via Response Surface Methodology (RSM)" that have been collected from Web of Science(C) and Scopus(C), and analyzed by using Bibliometrix, an RStudio package for science mapping analysis. Trends in the optimization and extraction methods of pectin via RSM have been pointed out, which may be useful for further research. Results shown that publications on "Pectin Extraction via RSM" have started for more than 20 years, with a growing trend, more than triplicating in the last 10 years. Based on such set of papers, China has been the most active country in local productions, whereas Iran, Brazil, India, and the United Kingdom have contributed with international-wide collaborative publications in optimization pectin extraction through RSM. Assisted extraction categories, physical and functional properties of pectin have taken on more relevance by 2012, especially with consolidation of microwave-assisted and ultrasound-assisted extraction techniques. -C1 [Filho, Luiz B. S.; Coelho, Ronaldo C.; Barbosa, Herbert de S.] Univ Fed Piaui, Chem Dept, Study Grp Bioanalyt GEBIO, BR-64049550 Teresina, PI, Brazil. - [Filho, Luiz B. S.; Coelho, Ronaldo C.] Fed Inst Piaui, Chem Dept, BR-64053390 Teresina, PI, Brazil. - [Muniz, Edvani C.] Univ Fed Piaui, Chem Dept, BR-64049550 Teresina, PI, Brazil. - [Muniz, Edvani C.] Univ Estadual Maringa, Chem Dept, BR-87020900 Maringa, Parana, Brazil. -C3 Universidade Federal do Piaui; Instituto Federal do Piaui (IFPI); - Universidade Federal do Piaui; Universidade Estadual de Maringa -RP Muniz, EC (corresponding author), Univ Estadual Maringa, Chem, Av Colombo 5790, BR-87020900 Maringa, Parana, Brazil. -EM munizec@ufpi.edu.br -RI ; MUNIZ, EDVANI/AAE-2397-2020; Barbosa, Herbert/N-9284-2014; Coelho, - Ronaldo/AIA-3003-2022; Muniz, Edvani/D-6543-2014 -OI Barbosa, Herbert/0000-0003-2094-7384; Filho, Luiz Brito de - Souza/0009-0000-2196-0981; Cunha Coelho, ronaldo/0000-0003-0800-5132; - Muniz, Edvani/0000-0001-6685-1519 -FU CNPq [307429/2018-0, 408767/2021-9]; Federal Institute of Piaui (IFPI) -FX The authors are grateful to Coordenac ~ao de Aperfeicoameneto de Pessoal - de Nivel Superior, CAPES, Brazil. 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Appl. -PD DEC -PY 2022 -VL 4 -AR 100229 -DI 10.1016/j.carpta.2022.100229 -PG 15 -WC Chemistry, Applied; Polymer Science -WE Emerging Sources Citation Index (ESCI) -SC Chemistry; Polymer Science -GA 2S1RW -UT WOS:000821578200005 -OA gold -DA 2025-07-11 -ER - -PT J -AU Moral-Muñoz, JA - Herrera-Viedma, E - Santisteban-Espejo, A - Cobo, MJ -AF Moral-Munoz, Jose A. - Herrera-Viedma, Enrique - Santisteban-Espejo, Antonio - Cobo, Manuel J. -TI Software tools for conducting bibliometric analysis in science: An - up-to-date review -SO PROFESIONAL DE LA INFORMACION -LA English -DT Review -DE Bibliometrics; Scientometrics; Science mapping analysis; Tools; - Bibliographic databases; Performance analysis; Software; Libraries; - R-package; Python-package; Software review -ID PUBLICATION YEAR SPECTROSCOPY; GOOGLE SCHOLAR; MAPPING SOFTWARE; - CITATION; WEB; SCOPUS; DIMENSIONS; REFERENCES; PATTERNS; COVERAGE -AB Bibliometrics has become an essential tool for assessing and analyzing the output of scientists, cooperation between universities, the effect of state-owned science funding on national research and development performance and educational efficiency, among other applications. Therefore, professionals and scientists need a range of theoretical and practical tools to measure experimental data. This review aims to provide an up-to-date review of the various tools available for conducting bibliometric and scientometric analyses, including the sources of data acquisition, performance analysis and visualization tools. The included tools were divided into three categories: general bibliometric and performance analysis, science mapping analysis, and libraries; a description of all of them is provided. A comparative analysis of the database sources support, pre-processing capabilities, analysis and visualization options were also provided in order to facilitate its understanding. Although there are numerous bibliometric databases to obtain data for bibliometric and scientometric analysis, they have been developed for a different purpose. The number of exportable records is between 500 and 50,000 and the coverage of the different science fields is unequal in each database. Concerning the analyzed tools, Bibliometrix contains the more extensive set of techniques and suitable for practitioners through Biblioshiny. VOSviewer has a fantastic visualization and is capable of loading and exporting information from many sources. SciMAT is the tool with a powerful pre-processing and export capability. In views of the variability of features, the users need to decide the desired analysis output and chose the option that better fits into their aims. -C1 [Moral-Munoz, Jose A.] Univ Cadiz, Inst Res & Innovat Biomed Sci Prov Cadiz INiB, Cadiz, Spain. - [Herrera-Viedma, Enrique] Univ Granada, ETS Ingn Informat & Telecomunicac, Periodista Daniel Saucedo Aranda S-N, Granada 18014, Spain. - [Santisteban-Espejo, Antonio] Puerta Mar Hosp, Div Hematol & Hemotherapy, Cadiz, Spain. - [Cobo, Manuel J.] Univ Cadiz, Dept Comp Sci & Engn, Cadiz, Spain. -C3 Universidad de Cadiz; University of Granada; Universidad de Cadiz -RP Cobo, MJ (corresponding author), Univ Cadiz, Dept Comp Sci & Engn, Cadiz, Spain. -EM joseantonio.moral@uca.es; viedma@decsai.ugr.es; - antonio.santisteban.sspa@juntadeandalucia.es; manueljesus.cobo@uca.es -RI Cobo, Manuel Jesus/C-5581-2011; HERRERA-VIEDMA, ENRIQUE/C-2704-2008; - Santisteban-Espejo, Antonio/AAA-8934-2019; Moral-Munoz, Jose - A./A-5893-2014; Herrera-Viedma, Enrique/C-2704-2008; Moral-Munoz, - Jose/A-5893-2014; Cobo Martí­n, Manuel Jesús/C-5581-2011 -OI Cobo, Manuel Jesus/0000-0001-6575-803X; Moral-Munoz, Jose - A./0000-0002-6465-982X; Herrera-Viedma, Enrique/0000-0002-7922-4984; -CR Alonso S, 2010, SCIENTOMETRICS, V82, P391, DOI 10.1007/s11192-009-0047-5 - Alonso S, 2009, J INFORMETR, V3, P273, DOI 10.1016/j.joi.2009.04.001 - [Anonymous], 2008, Reflections on the h-index - [Anonymous], 2018, APPL INTELL, DOI [10.1007/s10489-017-1105-y., DOI 10.1007/s10489-017-1105-y, DOI 10.1007/S10489-017-1105-Y] - [Anonymous], 2002, analytic technologies - [Anonymous], 2009, Science of Science (Sci2) Tool - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Asimov I., 2010, A Short History of Chemistry-an Introduction to the Ideas and Concepts of Chemistry - Batagelj V, 2004, MATH VIS, P77 - Börner K, 2003, ANNU REV INFORM SCI, V37, P179, DOI 10.1002/aris.1440370106 - Bornmann L, 2018, EMBO REP, V19, DOI 10.15252/embr.201847260 - Bornmann L, 2013, J INFORMETR, V7, P562, DOI 10.1016/j.joi.2013.02.005 - Bostock M, 2011, IEEE T VIS COMPUT GR, V17, P2301, DOI 10.1109/TVCG.2011.185 - Cabrerizo FJ, 2010, J INFORMETR, V4, P23, DOI 10.1016/j.joi.2009.06.005 - Chapman K, 2019, INT J LOGIST MANAG, V30, P1039, DOI 10.1108/IJLM-04-2019-0110 - Chen C, 2019, How to use CiteSpace - Chen CM, 2017, J DATA INFO SCI, V2, P1, DOI 10.1515/jdis-2017-0006 - Chen CM, 2006, J AM SOC INF SCI TEC, V57, P359, DOI 10.1002/asi.20317 - Cobo MJ, 2012, J AM SOC INF SCI TEC, V63, P1609, DOI 10.1002/asi.22688 - Cobo MJ, 2011, J AM SOC INF SCI TEC, V62, P1382, DOI 10.1002/asi.21525 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - Egghe L, 2006, SCIENTOMETRICS, V69, P131, DOI 10.1007/s11192-006-0144-7 - Ellegaard O, 2015, SCIENTOMETRICS, V105, P1809, DOI 10.1007/s11192-015-1645-z - Fabregat-Aibar L, 2019, SUSTAINABILITY-BASEL, V11, DOI 10.3390/su11092526 - Gagolewski M, 2011, J INFORMETR, V5, P678, DOI 10.1016/j.joi.2011.06.006 - Garfield E, 2003, J AM SOC INF SCI TEC, V54, P400, DOI 10.1002/asi.10226 - Glänzel W, 2012, PROF INFORM, V21, P194, DOI 10.3145/epi.2012.mar.11 - Grauwin S, 2011, SCIENTOMETRICS, V89, P943, DOI 10.1007/s11192-011-0482-y - Gusenbauer M, 2019, SCIENTOMETRICS, V118, P177, DOI 10.1007/s11192-018-2958-5 - Harzing A. 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The object of the analysis is scientific publications published in the Scopus database in the scientific field of the impact of sports on the economy. The study aims to fill the research gap in the bibliometric analysis of the impact of sports on the economy by providing an empirical contribution that reveals trends in the scientific literature on the impact of sports on the economy, the most productive researchers, institutions, countries, journals in this field of research, and identifying a bibliometric framework that includes networks between researchers. Scientific articles indexed in Scopus were analyzed with no specific time limits using bibliometric analysis methods-performance analysis, citation analysis, and science mapping. We employed performance analysis, citation analysis, and science mapping via the Bibliometrix package R Studio (R) and the VOSviewer. The results of the systematic review show that, according to the Scopus database, 801 authors have studied the impact of sports on the global economy, and 299 scientific articles have been published in various journals around the world during the study period. This relatively low number suggests insufficient attention on the part of researchers to the importance of the sports sector. The most active researchers are from the USA, the UK, and China. The most influential journals and research institutions have been identified. The study results showed disagreement between the authors in some areas of the study (economic impact of major sporting events, impact of new sports infrastructure on regional economic growth, illustrating the ongoing debates in the field. -C1 [Kudinska, Marina; Solovjova, Irina] Univ Latvia, Dept Finance & Accounting, Riga, Latvia. - [Korde, Zanete] Riga Stradins Univ, Dept Hlth Psychol & Pedag, Riga, Latvia. -C3 University of Latvia; Riga Stradins University -RP Kudinska, M (corresponding author), Univ Latvia, Dept Finance & Accounting, Riga, Latvia. -EM marina.kudinska@lu.lv -RI Kudinska, Marina/AAB-7289-2020; Solovjova, Irina/HLQ-2495-2023 -FX The author(s) declare that financial support was received for the - research and/or publication of this article. 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Sports Act. Living -PD MAY 7 -PY 2025 -VL 7 -AR 1545264 -DI 10.3389/fspor.2025.1545264 -PG 13 -WC Sport Sciences -WE Emerging Sources Citation Index (ESCI) -SC Sport Sciences -GA 2UN3B -UT WOS:001491635100001 -PM 40400787 -DA 2025-07-11 -ER - -PT J -AU Yadav, M - Banerji, P -AF Yadav, Mansi - Banerji, Priyanka -TI A bibliometric analysis of digital financial literacy -SO AMERICAN JOURNAL OF BUSINESS -LA English -DT Review -DE Bibliometric analysis; Digital finance; Science mapping; Retirement - planning; Saving behaviour; Bibliometrix -ID INFORMATION; SCIENCE -AB Purpose - There has been a great deal of exploratory, conceptual and empirical research on digital financial literacy (DFL) in the fields of finance, economics, business and management. But up until now, there has not been any attempt to provide a thorough scientific mapping of the area. Therefore, by combining various knowledge systems, this study seeks to identify the current research trend. Design/methodology/approach - A sample of 158 papers was subjected to bibliometric analysis in the areas of DFL or digital finance. Assembling, organising and evaluating are the three phases that make up the bibliometric analysis process derived from the most dependable and genuine sources, the Scopus database, and the Web of Science (WoS) database. This study was done using a scientific search technique on the Scopus and WoS databases for the years 2015 through 2022. The study made use of Biblioshiny, a web-based tool created in R-studio and part of the Bibliometrix package. Prominent journals, authors, nations, articles and themes were identified with the use of the software's automated workflow. "Citation, co-citation, and social network analysis" were also carried out.Findings - The study' outcomes indicate that, as an interdisciplinary discipline, the themes of digital finance have changed throughout time. Researchers first concentrated on socioeconomic and demographic variables, but over time the subject expanded to include themes like influencing, promoting, and behavioural factors that affect digital financial literacy (DFL). This research shows the conceptual framework of the area in addition to its intellectual and social structure. This study offers crucial insights into subjects that demand more research.Research limitations/implications - Since the current study is a bibliometric analysis, the usual restrictions on such studies apply. A meta-analysis, a thorough literature review and other methods would be beneficial for future researchers to develop a solid conceptual framework. This current research work's science mapping is restricted to the Scopus and WoS databases because this research includes more high-quality articles and has organised formats that work with the Bibliometrix application.Practical implications - Present research provides critical insights into saving behaviour, retirement planning, digital finance and the interdependence of these. This research highlights the most prevalent problems in the field and points in the direction of potential areas for further study. Exposing the social and intellectual structure of the domain educates upcoming scholars about the themes, contexts and opportunities for collaboration in this field.Social implications - The study will be useful for future learning as the study gives broad exposure to the current literature in the field of digital finance. On the other hand, people will also grow aware of the effects of digital finance and make the proper choices as a result. Additionally, the report might offer crucial insights for developing policies on digital finance and literacy.Originality/value - In the past, a significant number of conceptual and empirical studies were conducted internationally in the research fields of economics, finance, business, management and consumer behaviour. 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Addressing a gap in the literature, this research explores the patterns and trends of this intersection, which had not been holistically analyzed. The novelty of this study lies in its comprehensive identification of thematic clusters, publication trends, and key contributors to the field, providing a unique and detailed bibliometric perspective on how strategic leadership influences organizational innovation, particularly in the context of Industry 4.0 and technological advancements. Our findings reveal substantial growth in scholarly interest post-2005, peaking in 2020-2021, driven by the rise of Industry 4.0 and the increasing importance of leadership in fostering organizational innovation. The United States, China, and Australia are the leading contributors, with key institutions such as Tennessee Technological University and the University of Pretoria driving research in this field. The analysis, conducted using VOSviewer and Bibliometrix, identified five thematic clusters : strategic leadership traits, open innovation, leadership's impact on firm performance, competitive advantage, and contextual factors influencing leadership. This underscores the critical role of strategic leadership in navigating technological advancements and fostering organizational adaptability. Co-citation analysis highlighted seminal works by Bantel, Hambrick, and Howell, shaping the foundational frameworks of the field. Despite the inherent limitations of bibliometric methods, the study emphasizes the need for further exploration of emerging themes, such as CEO leadership styles, ambidexterity, and grassroots innovation. The findings suggest that adaptable leadership practices and enhanced collaboration between CEOs and Boards of Directors are vital in driving innovation and shaping governance structures. 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Res. -PD SEP-DEC -PY 2024 -VL 13 -IS 3 -BP 849 -EP 865 -DI 10.5530/jscires.20041230 -PG 17 -WC Information Science & Library Science -WE Emerging Sources Citation Index (ESCI) -SC Information Science & Library Science -GA X4T0U -UT WOS:001425281700005 -DA 2025-07-11 -ER - -PT J -AU Ribeiro, H - Barbosa, B - Moreira, AC - Rodrigues, R -AF Ribeiro, Hugo - Barbosa, Belem - Moreira, Antonio C. - Rodrigues, Ricardo -TI Churn in services - A bibliometric review -SO CUADERNOS DE GESTION -LA English -DT Review -DE Customer Churn; Bibliometric Analysis; Co-citation Analysis; - Bibliographic Coupling; Science Mapping; Biblioshiny -ID CUSTOMER SWITCHING BEHAVIOR; PARTIAL DEFECTION; PREDICTION; RETENTION; - TELECOMMUNICATION; MANAGEMENT; SCIENCE; DETERMINANTS; SATISFACTION; - ATTRITION -AB The purpose of this article is to identify the most impactful research on customer churn and to map the conceptual and intellectual structure of its field of study. Data were collected from the WoS database, comprising 338 articles published between 1995 and 2020. Several bibliometric techniques were applied, including analysis of co-words, co-citation, bibliographic coupling, and co-authorship networks. R software and the Bibliometrix/Biblioshiny package were used to perform the analyses. The results identify the most active and influential authors, articles, and journals on the topic. More specifically, through co-citations and bibliographic coupling, it was possible to map the oldest articles (retrospective analysis) and the current research front (prospective analysis). The retrospective analysis, based on co-citations, revealed that the foundations of this research field are constructs such as quality of service, satisfaction, loyalty, and changing behaviors. The prospective analysis, performed through bibliographic coupling, revealed that current research is embedded in predictive analysis, clusters, data mining, and algorithms. The results provide robust guidance for further investigation in this field. -C1 [Barbosa, Belem] Univ Porto, Sch Econ & Management, Porto, Portugal. - [Barbosa, Belem; Moreira, Antonio C.] Univ Aveiro, GOCVOPP Res Unit Governance Competitiveness & Pub, Aveiro, Portugal. - [Barbosa, Belem] Univ Porto, UPorto, Cef Up Ctr Econ & Finance, Porto, Portugal. - [Moreira, Antonio C.] Aveiro Univ, Dept Econ Management Ind Engn & Tourism, Aveiro, Portugal. - [Moreira, Antonio C.; Rodrigues, Ricardo] Univ Beira Interior, NECE UBI Res Ctr Business Sci, Covilha, Portugal. - [Moreira, Antonio C.] Univ Porto, Fac Engn, INESCTEC Inst Syst & Comp Engn Technol & Sci, Porto, Portugal. - [Rodrigues, Ricardo] Univ Beira Interior, Dept Business & Econ, Covilha, Portugal. -C3 Universidade do Porto; Universidade de Aveiro; Universidade do Porto; - Universidade de Aveiro; Universidade da Beira Interior; INESC TEC; - Universidade do Porto; Universidade da Beira Interior -RP Ribeiro, H (corresponding author), Aveiro Univ, Dept Econ Management Ind Engn & Tourism, Aveiro, Portugal. -EM hugo.ribeiro@ua.pt; 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Gest. -PY 2022 -VL 22 -IS 2 -BP 97 -EP 121 -DI 10.5295/cdg.211509hr -EA MAR 2022 -PG 25 -WC Business; Business, Finance; Management -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA 1K4DZ -UT WOS:000765441200001 -OA gold, Green Submitted -DA 2025-07-11 -ER - -PT J -AU Xu, F - Kasperskaya, Y - Sagarra, M -AF Xu, Feng - Kasperskaya, Yuliya - Sagarra, Marti -TI The impact of FinTech on bank performance: A systematic literature - review -SO DIGITAL BUSINESS -LA English -DT Review -DE FinTech; Bank performance; Bibliometric analysis; Digital banking; - Financial inclusion; Peer-to-peer lending; Risk management; Mobile - payments; Blockchain; Customer experience; Regulatory frameworks; - Financial stability -ID MOBILE MONEY SERVICES; EFFICIENCY; ADOPTION; KEYWORD; TOOL -AB This paper investigates the impact of financial technology (FinTech) on bank performance through a comprehensive bibliometric analysis of publications from the Web of Science Core Collection Database published between 2015 and July 2024. The study employs the R-package litsearchr for keyword search string development and uses VosViewer and Bibliometrix for science mapping and network analysis. The research addresses five key questions, including research trends, influential authors and sources, geographical influences, notable research clusters, and the aspects of bank performance affected by FinTech. The paper proposes four future research directions, suggesting the exploration of alternative bank performance metrics, greater regional focus, the investigation of emerging themes such as financial inclusion and the role of entrepreneurship, and advances in methodologies. 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Bus. -PD DEC -PY 2025 -VL 5 -IS 2 -AR 100131 -DI 10.1016/j.digbus.2025.100131 -PG 21 -WC Business; Management -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA 3KA0Z -UT WOS:001502186900001 -DA 2025-07-11 -ER - -PT J -AU Gora, K - Dhingra, B - Yadav, M -AF Gora, Kapil - Dhingra, Barkha - Yadav, Mahender -TI A bibliometric study on the role of micro-finance services in micro, - small and medium enterprises -SO COMPETITIVENESS REVIEW -LA English -DT Review -DE Micro-finance; Micro-credit; MSMEs; Bibliometric analysis; Content - analysis -ID MICROFINANCE EVIDENCE; POVERTY REDUCTION; ENTREPRENEURSHIP; - MICROENTERPRISES; GOVERNANCE; CREDIT; WOMEN -AB Purpose - Micro-finance has a significant role in the better performance of micro, small and medium enterprises (MSMEs). This study aims to provide a comprehensive picture of the existing literature on the role of micro-finance and its approaches in MSMEs. Design/methodology/approach - This work performs a bibliometric analysis using a data set of 631 articles collected from the Scopus database. The Bibliometrix R package and Vosviewer are used to conduct performance analysis and scientific mapping. Performance analysis shows the publication trend, key authors, journals and top influential articles. Science mapping through a bibliographic coupling network of documents is prepared to discover the intellectual structure of the field.Findings - This review has identified the four major themes: access to finance and schemes, women empowerment and poverty alleviation, the performance of micro-finance institutions and recent development in micro-financial institutions. With the help of these research themes, the paper also highlights future research agendas.Originality/value - This paper enriches the understanding of the role of micro-finance services in performance of entrepreneurship with the bibliometric review of top contributors. -C1 [Gora, Kapil; Dhingra, Barkha; Yadav, Mahender] Maharshi Dayanand Univ, Dept Commerce, Rohtak, India. -C3 Maharshi Dayanand University -RP Dhingra, B (corresponding author), Maharshi Dayanand Univ, Dept Commerce, Rohtak, India. -EM kapil.rs.comm@mdurohtak.ac.in; dhingrabarkha1611@gmail.com; - mahender46@gmail.com -RI Dhingra, Barkha/IWM-0155-2023; Yadav, Mahender/IWV-1304-2023 -OI Dhingra, Barkha/0000-0002-6459-4261 -CR Agarwala V, 2022, J DEV ENTREP, V27, DOI 10.1142/S1084946722500054 - Akter S, 2021, INT J SOC ECON, V48, P399, DOI 10.1108/IJSE-08-2020-0545 - Allison TH, 2013, J BUS VENTURING, V28, P690, DOI 10.1016/j.jbusvent.2013.01.003 - Alvarez SA, 2014, ENTREP THEORY PRACT, V38, P159, DOI 10.1111/etap.12078 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Attanasio O, 2015, AM ECON J-APPL ECON, V7, P90, DOI 10.1257/app.20130489 - Banerjee A, 2015, AM ECON J-APPL ECON, V7, P22, DOI 10.1257/app.20130533 - Banerjee SB, 2017, HUM RELAT, V70, P63, DOI 10.1177/0018726716640865 - Bartolini M, 2019, J CLEAN PROD, V226, P242, DOI 10.1016/j.jclepro.2019.04.055 - Basto M.A., 2020, J SECURITY SUSTAINAB, V10, P203, DOI [10.9770/jssi.2020.10.1(15), DOI 10.9770/JSSI.2020.10.1(15)] - Batra S., 2022, IUP J CORPORATE GOVE, V21, P39 - Batra S, 2023, INT J LAW MANAG, V65, P333, DOI 10.1108/IJLMA-01-2023-0001 - Batra S, 2023, MANAG FINANC, V49, P992, DOI 10.1108/MF-07-2022-0330 - Berg G, 2012, J FINANC INTERMED, V21, P549, DOI 10.1016/j.jfi.2012.05.003 - Berge LIO, 2015, MANAGE SCI, V61, P707, DOI 10.1287/mnsc.2014.1933 - Bhatnagar S, 2022, RENEW SUST ENERG REV, V162, DOI 10.1016/j.rser.2022.112405 - Block J.H., 2020, Management Review Quarterly, V70, P307, DOI DOI 10.1007/S11301-020-00188-4 - Bradley SW, 2012, J MANAGE STUD, V49, P684, DOI [10.1111/j.1467-6486.2012.01043.x, 10.1111/J.1467-6486.2012.01043.X] - Brana S, 2013, SMALL BUS ECON, V40, P87, DOI 10.1007/s11187-011-9346-3 - Brau J.C., 2004, J ENTREPRENEURIAL FI, V9, P1 - Brett JA, 2006, HUM ORGAN, V65, P8, DOI 10.17730/humo.65.1.6wvq3ea7pbl38mub - Bruton G, 2015, ENTREP THEORY PRACT, V39, P9, DOI 10.1111/etap.12143 - Buckley G, 1997, WORLD DEV, V25, P1081, DOI 10.1016/S0305-750X(97)00022-3 - Chakrabarty S, 2015, J BUS ETHICS, V126, P487, DOI 10.1007/s10551-013-1963-0 - Chakrabarty S, 2014, J BUS ETHICS, V119, P529, DOI 10.1007/s10551-013-1833-9 - Chliova M, 2015, J BUS VENTURING, V30, P467, DOI 10.1016/j.jbusvent.2014.10.003 - Columba F, 2010, J FINANC STABIL, V6, P45, DOI 10.1016/j.jfs.2009.12.002 - Das S. 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Rev. -PD JUN 4 -PY 2024 -VL 34 -IS 4 -BP 718 -EP 735 -DI 10.1108/CR-11-2022-0174 -EA JUL 2023 -PG 18 -WC Business -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA SP5D1 -UT WOS:001021394600001 -DA 2025-07-11 -ER - -PT J -AU Sujono, RI - Rosari, R - Santoso, CB - Susamto, AA -AF Sujono, Rusny Istiqomah - Rosari, Reni - Santoso, Claudius Budi - Susamto, Akhmad Akbar -TI Bibliometric analysis of organizational learning in philanthropic - organizations -SO LEARNING ORGANIZATION -LA English -DT Article; Early Access -DE Organizational learning; Philanthropy; Bibliometrics -ID KNOWLEDGE; PERFORMANCE -AB Purpose-This study aims to examine publishing patterns regarding the incorporation of organizational learning in philanthropic organizations. Design/methodology/approach-This study conducts a quantitative bibliometric analysis using Scopus database data from 1997 to 2024. The search terms "organizational learning" combined with "philanthropy," "non-profit," "nonprofit," "charity," "humanitarian" or "endowment" yielded 162 articles. The data were processed in RStudio using the Bibliometrix R package, specifically the Biblioshiny component. Findings-The results of the bibliometric analysis indicate a significant increase in research interest in the theme of organizational learning within philanthropic organizations from 1997 to 2024. This analysis also elucidates the relationships among the most prolific authors based on the country of their affiliated universities, the collaborations that have taken place, the most cited documents, keywords and the scientific knowledge used. Research limitations/implications-A comprehensive literature review will be valuable for future researchers aiming to build a robust conceptual framework. This study's science mapping is limited to the Scopus database and languages. Originality/value-To the best of the authors' knowledge, this study is the first to describe research patterns focusing on organizational learning in philanthropic organizations. -C1 [Sujono, Rusny Istiqomah; Rosari, Reni; Santoso, Claudius Budi; Susamto, Akhmad Akbar] Univ Gadjah Mada, Grad Sch, Doctoral Program Islamic Econ & Halal Ind, Yogyakarta, Indonesia. - [Sujono, Rusny Istiqomah] Univ Alma Ata, Fac Econ & Business, Dept Islamic Econ, Yogyakarta, Indonesia. - [Rosari, Reni; Santoso, Claudius Budi] Univ Gadjah Mada, Fac Econ & Business, Dept Management, Yogyakarta, Indonesia. - [Susamto, Akhmad Akbar] Univ Gadjah Mada, Fac Econ & Business, Dept Econ, Yogyakarta, Indonesia. -C3 Gadjah Mada University; Gadjah Mada University; Gadjah Mada University -RP Sujono, RI (corresponding author), Univ Gadjah Mada, Grad Sch, Doctoral Program Islamic Econ & Halal Ind, Yogyakarta, Indonesia.; Sujono, RI (corresponding author), Univ Alma Ata, Fac Econ & Business, Dept Islamic Econ, Yogyakarta, Indonesia. -EM rusny.istiqomah.s@mail.ugm.ac.id; rrosari@ugm.ac.id; bsantoso@ugm.ac.id; - akhmad.susamto@ugm.ac.id -RI Rosari, Reni/GLV-5571-2022 -FU Indonesian Education Scholarship; Completion of Doctoral Studies - Research Program -FX The authors extend their heartfelt gratitude to the Indonesian Education - Scholarship for their generous support. 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Organ. -PD 2025 FEB 10 -PY 2025 -DI 10.1108/TLO-01-2024-0006 -EA FEB 2025 -PG 21 -WC Management -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA W1B1K -UT WOS:001416003500001 -DA 2025-07-11 -ER - -PT J -AU Gupta, A - Mishra, S - Behera, DK -AF Gupta, Anju - Mishra, Shekhar - Behera, Deepak Kumar -TI Tracing the trajectory of financial vulnerability: a systematic review - and bibliometric analysis -SO COGENT ECONOMICS & FINANCE -LA English -DT Review -DE Financial vulnerability; systematic literature review; bibliometric - study; household financial vulnerability; biblio-science mapping -ID SELF-CONTROL; CREDIT; INCOME; DEBT; ORGANIZATIONS; CONSTRAINTS; - MANAGEMENT; LITERACY; WORKING; SCIENCE -AB Over the span of 40 years, a substantial number of conceptual and empirical studies have been conducted on financial vulnerability (henceforth FV). These studies primarily covered socioeconomics, finance, management, and medicine. However, there is a paucity of comprehensive reviews and scientific mapping of the extant literature in the FV domain. Bibliometric analysis attempts to provide quantitative and qualitative knowledge in this area. This study was based on a review of 475 articles published in Scopus-indexed journals from 1990 to 2023. The present study employed the Biblioshiny R studio Bibliometrix package for data extraction and analysis. Our analysis provides information on recent publication trends; prominent authors, institutes, and countries; citations; thematic groups; keyword analysis; and social network analysis to identify influential work in this research domain and future gaps. The present analysis contributes to consolidating the existing fragmented literature on FV and highlights its significance during the current pandemic. 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Financ. -PD DEC 31 -PY 2024 -VL 12 -IS 1 -AR 2411566 -DI 10.1080/23322039.2024.2411566 -PG 23 -WC Economics -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA I6I2H -UT WOS:001331268300001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Dewamuni, Z - Shanmugam, B - Azam, S - Thennadil, S -AF Dewamuni, Zenith - Shanmugam, Bharanidharan - Azam, Sami - Thennadil, Suresh -TI Bibliometric Analysis of IoT Lightweight Cryptography -SO INFORMATION -LA English -DT Review -DE bibliometric analysis; lightweight cipher algorithm; IoT security -AB In the rapidly developing world of the Internet of Things (IoT), data security has become increasingly important since massive personal data are collected. IoT devices have resource constraints, which makes traditional cryptographic algorithms ineffective for securing IoT devices. To overcome resource limitations, lightweight cryptographic algorithms are needed. To identify research trends and patterns in IoT security, it is crucial to analyze existing works, keywords, authors, journals, and citations. We conducted a bibliometric analysis using performance mapping, science mapping, and enrichment techniques to collect the necessary information. Our analysis included 979 Scopus articles, 214 WOS articles, and 144 IEEE Xplore articles published during 2015-2023, and duplicates were removed. We analyzed and visualized the bibliometric data using R version 4.3.1, VOSviewer version 1.6.19, and the bibliometrix library. We discovered that India is the leading country for this type of research. Archarya and Bansod are the most relevant authors; lightweight cryptography and cryptography are the most relevant terms; and IEEE Access is the most significant journal. 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Within the Ibero-American region, a community of researchers specializing in Human-computer interaction and related interdisciplinary domains has been established. Hence, it is crucial to understand this field's current state and evolution to identify critical contributors, institutions, information sources, and knowledge networks. This knowledge enables the contextualization of research, project planning, resource management, and improved dissemination within the domain. This study employed the Science Mapping Workflow methodology and specialized tools like Bibliometrix to conduct a bibliometric analysis of Human-computer interaction in Ibero-America. The findings reveal that the domain is well-established at the Ibero-American level and exhibits a growth rate of 14.65% in publications, indicating consistent progress. Moreover, Spain and Brazil have emerged as leading contributors in this field. Regarding the knowledge structure, it is evident that numerous technological advancements are focused on enhancing the capabilities of individuals with disabilities or limitations. 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We offer, in an original manner, descriptive statistics and relevant landmarks of the sources, authors, publications, organizations, and countries that have contributed significantly to the development of research in this field. 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To guide future research, we conducted a bibliometric analysis of laser applications in eye diseases from 1990 to 2022, aiming to identify key themes and trends. Methods: We retrieved 3027 publications from the Web of Science Core Collection (WoSCC). Bibliometrix was used for science mapping of the literature, while VOSviewer and CiteSpace were applied to visualize co-authorship, co-citation, co-occurrence, and bibliographic coupling networks. Results: From a co-citation reference network, we identified 52 distinct clusters. Our analysis uncovered three main research trends. The first trend revolves around the potential evolution of corneal laser surgery techniques, shifting from the treatment of refractive errors to broader applications in biomedical optics. The second trend illustrates the advancement of laser applications in treating a range of disorders, from retinal and ocular surface diseases to glaucoma. The third trend focuses on the innovative uses of established technologies. Conclusion: This study offers significant insights into the evolution of laser applications in ophthalmology over the past 30 years, which will undoubtedly assist scientists in directing further research in this promising field. -C1 [Jiang, Yaping; Cai, Yuying; Zhang, Xin; Chen, Li; Chen, Yihui] Tongji Univ, Yangpu Hosp, Sch Med, Dept Ophthalmol, 50 Tengyue Rd, Shanghai 200090, Peoples R China. - [Zhou, Xingtao] Fudan Univ, Eye Inst, 19 Baoqing Rd, Shanghai 200031, Peoples R China. - [Zhou, Xingtao] Fudan Univ, Eye & ENT Hosp, Inst Med & Engn Innovat, Dept Ophthalmol, 19 Baoqing Rd, Shanghai 200031, Peoples R China. - [Zhou, Xingtao] Fudan Univ, Chinese Acad Med Sci, NHC Key Lab Myopia, Key Lab Myopia, 19 Baoqing Rd, Shanghai 200031, Peoples R China. -C3 Tongji University; Fudan University; Fudan University; Fudan University; - Chinese Academy of Medical Sciences - Peking Union Medical College -RP Chen, YH (corresponding author), Tongji Univ, Yangpu Hosp, Sch Med, Dept Ophthalmol, 50 Tengyue Rd, Shanghai 200090, Peoples R China.; Zhou, XT (corresponding author), Fudan Univ, Eye Inst, 19 Baoqing Rd, Shanghai 200031, Peoples R China.; Zhou, XT (corresponding author), Fudan Univ, Eye & ENT Hosp, Inst Med & Engn Innovat, Dept Ophthalmol, 19 Baoqing Rd, Shanghai 200031, Peoples R China.; Zhou, XT (corresponding author), Fudan Univ, Chinese Acad Med Sci, NHC Key Lab Myopia, Key Lab Myopia, 19 Baoqing Rd, Shanghai 200031, Peoples R China. -EM doctzhouxingtao@163.com; 1300089@tongji.edu.cn -RI ; Zhou, Xingtao/F-2927-2019 -OI Zhou, Xingtao/0000-0002-3465-1579; -FU National Natural Science Foundation of China [82271050, 82301175]; - Yangfan Plan of Shanghai Science and Technology Commission [22YF1443100] -FX Funding This work was funded by the National Natural Science Foundation - of China to YHC (82271050) and YPJ (82301175) . 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Ophthalmol. -PY 2024 -VL 18 -BP 1313 -EP 1328 -DI 10.2147/OPTH.S458840 -PG 16 -WC Ophthalmology -WE Emerging Sources Citation Index (ESCI) -SC Ophthalmology -GA RE9M7 -UT WOS:001226109900001 -PM 38765459 -OA Green Published, gold -DA 2025-07-11 -ER - -PT J -AU Kaya, A -AF Kaya, Ayla -TI Bibliometric Analysis of the 40-Year History of Public Health - Nursing (1984-2024) -SO PUBLIC HEALTH NURSING -LA English -DT Article; Early Access -DE bibliometrics; Public Health Nursing; science mapping; Web of Science - Core Collection -ID COMMUNITY -AB Objective: This study was conducted in honor of Public Health Nursing's 40th anniversary. The study was unique as it provided the first bibliometric analysis revealing the evolution of Public Health Nursing's publications. Design and Methods: This study was a bibliometric analysis. The study was carried out by analyzing 2985 publications. Data were collected from the Web of Science Core Collection (WoSCC) database on December 31, 2024. The data analysis and graphical presentation were conducted using the Bibliometrix Package in R software and WoSCC. Results: Public Health Nursing has had a rapidly growing impact on the field of public health nursing in terms of publications and citations. The most productive and collaborative country was the United States. "COVID-19," "vaccination," "older adults," "knowledge," "climate change," and "attitude" were the trending topics in recent years. According to the thematic map, more studies addressing the topics of "physical activity, obesity, adolescents" were required. Conclusion: The journal has an increasing contribution and impact on public health nursing studies. It was determined that the journal's publishing network was in good condition worldwide, and the thematic diversity was high. In addition, focusing on the topics that need further study can contribute to the field of public health nursing. -C1 [Kaya, Ayla] Akdeniz Univ, Fac Nursing, Pediat Nursing Dept, Antalya, Turkiye. -C3 Akdeniz University -RP Kaya, A (corresponding author), Akdeniz Univ, Fac Nursing, Pediat Nursing Dept, Antalya, Turkiye. -EM aylakaya@akdeniz.edu.tr -CR Akgöz AD, 2025, PUBLIC HEALTH NURS, V42, P494, DOI 10.1111/phn.13472 - Alasagheirin M, 2024, PUBLIC HEALTH NURS, V41, P151, DOI 10.1111/phn.13258 - [Anonymous], 2024, SCImago - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Azizo F, 2024, J PEDIATR NURS, V79, pe213, DOI 10.1016/j.pedn.2024.10.024 - Cava MA, 2005, PUBLIC HEALTH NURS, V22, P398, DOI 10.1111/j.0737-1209.2005.220504.x - Cinar IO, 2025, J PEDIATR NURS, V80, pe24, DOI 10.1016/j.pedn.2024.10.036 - Clarivate, 2024, Web of Science - DiCasmirro J, 2025, PUBLIC HEALTH NURS, V42, P604, DOI 10.1111/phn.13464 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Ern J, 2023, PUBLIC HEALTH NURS, V40, P535, DOI 10.1111/phn.13198 - Ho MTH, 2025, EUR NEUROPSYCHOPHARM, V92, P10, DOI 10.1016/j.euroneuro.2024.11.011 - Kaya A, 2024, CANCER NURS, V47, P252, DOI 10.1097/NCC.0000000000001324 - Kaya A, 2022, J PEDIATR NURS, V65, P69, DOI 10.1016/j.pedn.2022.03.014 - Köse SK, 2024, MEDICINE, V103, DOI 10.1097/MD.0000000000039241 - Li N, 2024, PUBLIC HEALTH NURS, V41, P255, DOI 10.1111/phn.13275 - López-Robles JR, 2021, APPL INTELL, V51, P6547, DOI 10.1007/s10489-021-02584-z - Merigó JM, 2015, J BUS RES, V68, P2645, DOI 10.1016/j.jbusres.2015.04.006 - Montazeri A., 2023, Whole Report - Musio ME, 2025, PUBLIC HEALTH NURS, V42, P996, DOI 10.1111/phn.13471 - Recto P, 2023, PUBLIC HEALTH NURS, V40, P63, DOI 10.1111/phn.13144 - Scott S., 2020, Witness: The Canadian Journal of Critical Nursing Discourse, V2, P111, DOI [10.25071/2291-5796.49, DOI 10.25071/2291-5796.49] - SHAMANSKY SL, 1984, PUBLIC HEALTH NURS, V1, P1, DOI 10.1111/j.1525-1446.1984.tb00424.x - Su YB, 2020, J NURS MANAGE, V28, P317, DOI 10.1111/jonm.12925 - Swider SM, 2002, PUBLIC HEALTH NURS, V19, P11, DOI 10.1046/j.1525-1446.2002.19003.x - Tayhan A, 2025, PUBLIC HEALTH NURS, V42, P113, DOI 10.1111/phn.13469 - Tripathi M, 2018, COLLNET J SCIENTOMET, V12, P215, DOI 10.1080/09737766.2018.1436951 - Warnes Gregory R., 2024, gplots: Various R programming tools for plotting data - White B, 2024, PUBLIC HEALTH NURS, V41, P543, DOI 10.1111/phn.13297 - Yalnkaya T., 2025, ThirtyFive Years of Knowledge in Transcultural Nursing: A Bibliometric Analysis of Journal of Transcultural Nursing, DOI [10.1177/1043659625133029, DOI 10.1177/1043659625133029] - Yu JX, 2025, PUBLIC HEALTH NURS, V42, P754, DOI 10.1111/phn.13517 - Zeleznik D, 2017, J ADV NURS, V73, P2407, DOI 10.1111/jan.13296 - Zhu JW, 2020, SCIENTOMETRICS, V123, P321, DOI 10.1007/s11192-020-03387-8 -NR 33 -TC 0 -Z9 0 -U1 6 -U2 6 -PU WILEY -PI HOBOKEN -PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA -SN 0737-1209 -EI 1525-1446 -J9 PUBLIC HEALTH NURS -JI Public Health Nurs. -PD 2025 MAY 19 -PY 2025 -DI 10.1111/phn.13574 -EA MAY 2025 -PG 9 -WC Public, Environmental & Occupational Health; Nursing -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Public, Environmental & Occupational Health; Nursing -GA 2ST5A -UT WOS:001490432000001 -PM 40387061 -DA 2025-07-11 -ER - -PT J -AU Mishra, M - Sudarsan, D - Santos, CAG - Mishra, SK - Kar, D - Baral, K - Pattnaik, N -AF Mishra, Manoranjan - Sudarsan, Desul - Santos, Celso Augusto Guimaraes - Mishra, Shailendra Kumar - Kar, Dipika - Baral, Kabita - Pattnaik, Namita -TI An overview of research on natural resources and indigenous communities: - a bibliometric analysis based on Scopus database (1979-2020) -SO ENVIRONMENTAL MONITORING AND ASSESSMENT -LA English -DT Article -DE Science mapping; Workflow; Cocitation; Scientometrics; Bibliographic - databases; VOSviewer -ID KNOWLEDGE; SCIENCE; BIODIVERSITY; IMPACTS -AB Indigenous people constitute an important section of society in many countries. Despite being a numerically smaller section, they are culturally diverse and distributed mostly in valuable natural resources-rich regions worldwide. In the era of globalization, industrialization, and trade liberalization, indigenous communities have become more vulnerable to displacement, land alienation, cultural erosion, and social exclusion. During the last few decades, researchers have tried to evaluate and document their problems and prospects. The present study analyzes the trends and characteristics of research and development conducted about indigenous communities. The research hotspots based on keywords, productive researchers, and journals during 1979-2020 were mapped using the Scopus database. The analysis was carried out using the bibliometrix R-package and VOSviewer software tool. Consistent growth in the number of studies and citations on indigenous communities concerning environmental conservation, natural resources, and economic development was observed during the last four decades. The present findings reveal that research on the indigenous community has attracted the attention of the scientific community in recent years. Qualitative studies with methodological rigor, having potential for social and policy implications, are warranted to understand and respect ingrained cultural and socio-economic diversity among these communities. -C1 [Mishra, Manoranjan; Kar, Dipika; Baral, Kabita] Khallikote Univ, Dept Nat Resources Management & Geoinformat, Berhampur 768003, Odisha, India. - [Sudarsan, Desul] Khallikote Univ, Dept Lib & Informat Sci, Berhampur, India. - [Santos, Celso Augusto Guimaraes] Univ Fed Paraiba, Dept Civil & Environm Engn, BR-58051900 Joao Pessoa, Paraiba, Brazil. - [Mishra, Shailendra Kumar] Univ Allahabad, Dept Anthropol, Allahabad 211002, Uttar Pradesh, India. - [Pattnaik, Namita] Govt Autonomous Coll, Dept Geog, Anugul, Odisha, India. -C3 Universidade Federal da Paraiba; University of Allahabad -RP Santos, CAG (corresponding author), Univ Fed Paraiba, Dept Civil & Environm Engn, BR-58051900 Joao Pessoa, Paraiba, Brazil. -EM celso@ct.ufpb.br -RI Santos, Celso Augusto Guimaraes/G-1816-2010; MISHRA, - SHAILENDRA/AGE-9749-2022; MISHRA, MANORANJAN/GQQ-5018-2022; Pattnaik, - Namita/ABB-5264-2020; Sudarsana, Desul/NDS-5488-2025; Santos, - Celso/G-1816-2010 -OI Santos, Celso Augusto Guimaraes/0000-0001-7927-9718; Sudarsan, - Desul/0000-0003-4867-236X; Mishra, Shailendra/0000-0002-1840-0374; - BARAL, KABITA/0000-0003-0241-738X -FU Ministry of Human Resource Development/Indian Council of Social Science - Research, Aruna Asaf Ali Marg, New Delhi [110067, - IMPRESS/P876/39/18-19/ICSSR] -FX This study was financed by the Ministry of Human Resource - Development/Indian Council of Social Science Research, Aruna Asaf Ali - Marg, New Delhi 110067, under the scheme of Impactful Policy Research in - Social Science with grant number IMPRESS/P876/39/18-19/ICSSR Project. -CR Alstadsaeter A., 2015, Who owns the wealth in the tax heavens - Anderson MK, 2005, TENDING THE WILD: NATIVE AMERICAN KNOWLEDGE AND THE MANAGEMENT OF CALIFORNIA'S NATURAL RESOURCES, P1 - [Anonymous], 2006, TRADITIONAL ECOLOGIC - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Baier-Fuentes H, 2019, INT ENTREP MANAG J, V15, P385, DOI 10.1007/s11365-017-0487-y - CALLON M, 1983, SOC SCI INFORM, V22, P191, DOI 10.1177/053901883022002003 - Castro AlfansoPeter., 2001, ENVIRON SCI POLICY, V4, P229, DOI DOI 10.1016/S1462-9011(01)00022-3 - Chapin M, 2005, ANNU REV ANTHROPOL, V34, P619, DOI 10.1146/annurev.anthro.34.081804.120429 - Chen C., 2014, The CiteSpace Manual (Version 0.65), V1, P1 - Cobo MJ, 2012, J AM SOC INF SCI TEC, V63, P1609, DOI 10.1002/asi.22688 - Cobo MJ, 2011, J AM SOC INF SCI TEC, V62, P1382, DOI 10.1002/asi.21525 - Commander Simon., 1981, Journal of Peasant Studies, V9, P86, DOI DOI 10.1080/03066158108438155 - Cox PA, 2000, SCIENCE, V287, P44, DOI 10.1126/science.287.5450.44 - DELORIA V, 1981, ANN AM ACAD POLIT SS, V454, P139, DOI 10.1177/000271628145400112 - Ding Helen, 2016, Climate Benefits, Tenure Costs: The Economic Case for Securing Indigenous Land Rights in the Amazon - Finer M, 2008, PLOS ONE, V3, DOI 10.1371/journal.pone.0002932 - Fredrik Danell, 2009, CELEBRATING SCHOLARL, V5 - GADGIL M, 1993, AMBIO, V22, P151 - Godoy R, 2005, ANNU REV ANTHROPOL, V34, P121, DOI 10.1146/annurev.anthro.34.081804.120412 - Hood WW, 2001, SCIENTOMETRICS, V52, P291, DOI 10.1023/A:1017919924342 - Jacquelin-Anderson P., 2018, The Indigenous World 2018 - KESSLER MM, 1963, AM DOC, V14, P10, DOI 10.1002/asi.5090140103 - Koocheki AA., 2003, 1 INT S SAFFR BIOL B, V650, P175 - Koseoglu MA, 2016, BRQ-BUS RES Q, V19, P153, DOI 10.1016/j.brq.2016.02.001 - Lawler JJ, 2014, P NATL ACAD SCI USA, V111, P7492, DOI 10.1073/pnas.1405557111 - Lockwood M, 2010, J ENVIRON MANAGE, V91, P754, DOI 10.1016/j.jenvman.2009.10.005 - Mantyka-Pringle CS, 2017, ENVIRON INT, V102, P125, DOI 10.1016/j.envint.2017.02.008 - Merigó JM, 2018, INFORM SCIENCES, V432, P245, DOI 10.1016/j.ins.2017.11.054 - Mishra Manoranjan, 2020, Journal of Urban and Environmental Engineering (JUEE), V14, P69, DOI 10.4090/juee.2020.v14n1.069077 - Mowat Hannah, 2019, IPCC CALLS SECURING - Notess L., 2018, The Scramble for Land Rights - PETERS HPF, 1991, SCIENTOMETRICS, V20, P235, DOI 10.1007/BF02018157 - Pierotti R, 2000, ECOL APPL, V10, P1333, DOI 10.2307/2641289 - PRITCHARD A, 1969, J DOC, V25, P348 - Reytar K., 2017, 5 Maps Show How Important Indigenous Peoples and Local Communities Are to the Environment - Ruffing T., 1979, REV RADICAL POL ECON, V11, P25, DOI [10.1177/048661347901100203, DOI 10.1177/048661347901100203] - Sangha K., 2020, SSRN ELECT J, DOI [10.2139/ssrn.3596050, DOI 10.2139/SSRN.3596050] - SMALL H, 1973, J AM SOC INFORM SCI, V24, P265, DOI 10.1002/asi.4630240406 - UN Environment Programme, 2017, IND PEOPL NAT TRAD C - van Eck N.J., 2011, Text mining and visualization using VOSviewer - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Whyte KP, 2013, CLIMATIC CHANGE, V120, P517, DOI 10.1007/s10584-013-0743-2 - Wildcat D., 2000, Indigenous Nations Studies Journal, V1, P61 - Worldbank, 2019, INDIGENOUS PEOPLES -NR 44 -TC 54 -Z9 55 -U1 0 -U2 33 -PU SPRINGER -PI DORDRECHT -PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS -SN 0167-6369 -EI 1573-2959 -J9 ENVIRON MONIT ASSESS -JI Environ. Monit. Assess. -PD JAN 13 -PY 2021 -VL 193 -IS 2 -AR 59 -DI 10.1007/s10661-020-08793-2 -PG 17 -WC Environmental Sciences -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Environmental Sciences & Ecology -GA PV2IF -UT WOS:000609815400002 -PM 33442808 -DA 2025-07-11 -ER - -PT J -AU Yalcinkaya, T - Yucel, SC -AF Yalcinkaya, Turgay - Yucel, Sebnem Cinar -TI Mobile learning in nursing education: A bibliometric analysis and - visualization -SO NURSE EDUCATION IN PRACTICE -LA English -DT Article -DE Bibliometrics analysis; Mobile learning; Nursing education; Nursing - students; Knowledge synthesis -ID PERSUASIVE TECHNOLOGY; STUDENTS KNOWLEDGE; PATIENTS PRETEST; - SMARTPHONES; DEVICES; TRENDS; NURSES; SKILLS; APPS; CARE -AB Aim: This study performed a bibliometric analysis of studies related to mobile learning in the field of nursing education. Methods: The Scopus database was used to determine the most frequently cited studies on mobile learning in nursing education. VOSviewer and Bibliometrix were employed for bibliometric analysis and visualization. Science mapping and performance analysis was adopted from bibliometric analysis techniques. In addition, a synthetic knowledge synthesis approach was used. Results: A total of 234 publications were published in 107 sources in 2002-2023. The publications had 8797 citations, an average of 88 citations per publication. In terms of total link strength (TLS), links, a number of articles and citations, the US led all other countries in the field. Regarding authors, Hwang was the most frequently cited authors (n = 348). According to trend topics analysis, the keywords "gamification", "simulation", "attitude", "clinical competence" and "online learning" have emerged in the field. Conclusion: Research on mobile learning in nursing education has been increasing in recent years. 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Pract. -PD AUG -PY 2023 -VL 71 -AR 103714 -DI 10.1016/j.nepr.2023.103714 -EA AUG 2023 -PG 11 -WC Nursing -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Nursing -GA R6MY4 -UT WOS:001065489900001 -PM 37552905 -DA 2025-07-11 -ER - -PT J -AU Chen, ZY - Liu, ZL - Feng, YL - Shi, AC - Wu, LQ - Sang, Y - Li, CX -AF Chen, Ziyi - Liu, Zhiliang - Feng, Yali - Shi, Aochen - Wu, Liqing - Sang, Yi - Li, Chenxi -TI Global research on RNA vaccines for COVID-19 from 2019 to 2023: a - bibliometric analysis -SO FRONTIERS IN IMMUNOLOGY -LA English -DT Article -DE COVID-19; SARS-CoV-2; RNA vaccines; web of science; bibliometrics -AB Background Since the global pandemic of COVID-19 has broken out, thousands of pieces of literature on COVID-19 RNA vaccines have been published in various journals. The overall measurement and analysis of RNA vaccines for COVID-19, with the help of sophisticated mathematical tools, could provide deep insights into global research performance and the collaborative architectural structure within the scientific community of COVID-19 mRNA vaccines. In this bibliometric analysis, we aim to determine the extent of the scientific output related to COVID-19 RNA vaccines between 2019 and 2023.Methods We applied the Bibliometrix R package for comprehensive science mapping analysis of extensive bibliographic metadata retrieved from the Web of Science Core Collection database. On January 11th, 2024, the Web of Science database was searched for COVID-19 RNA vaccine-related publications using predetermined search keywords with specific restrictions. Bradford's law was applied to evaluate the core journals in this field. The data was analyzed with various bibliometric indicators using the Bibliometrix R package.Results The final analysis included 2962 publications published between 2020 and 2023 while there is no related publication in 2019. The most productive year was 2022. The most relevant leading authors in terms of publications were Ugur Sahin and Pei-Yong, Shi, who had the highest total citations in this field. The core journals were Vaccines, Frontiers in Immunology, and Viruses-Basel. The most frequently used author's keywords were COVID-19, SARS-CoV-2, and vaccine. Recent COVID-19 RNA vaccine-related topics included mental health, COVID-19 vaccines in humans, people, and the pandemic. Harvard University was the top-ranked institution. The leading country in terms of publications, citations, corresponding author country, and international collaboration was the United States. The United States had the most robust collaboration with China.Conclusion The research hotspots include COVID-19 vaccines and the pandemic in people. We identified international collaboration and research expenditure strongly associated with COVID-19 vaccine research productivity. Researchers' collaboration among developed countries should be extended to low-income countries to expand COVID-19 vaccine-related research and understanding. -C1 [Chen, Ziyi; Li, Chenxi] Nanchang Univ, Affiliated Hosp 1, Jiangxi Med Coll, Ctr Mol Diag & Precis Med, Nanchang, Peoples R China. - [Chen, Ziyi; Shi, Aochen; Wu, Liqing; Sang, Yi; Li, Chenxi] First Hosp Nanchang, Jiangxi Key Lab Canc Metastasis & Precis Treatment, Nanchang, Peoples R China. - [Liu, Zhiliang] Jiangxi Canc Hosp, Dept Pathol, Nanchang, Peoples R China. - [Feng, Yali] Jiangxi Prov Chest Hosp, Dept Pathol, Nanchang, Peoples R China. -C3 Nanchang University -RP Li, CX (corresponding author), Nanchang Univ, Affiliated Hosp 1, Jiangxi Med Coll, Ctr Mol Diag & Precis Med, Nanchang, Peoples R China.; Sang, Y; Li, CX (corresponding author), First Hosp Nanchang, Jiangxi Key Lab Canc Metastasis & Precis Treatment, Nanchang, Peoples R China. -EM ndsfy001889@ncu.edu.cn; pamelalee@nwafu.edu.cn -RI Li, Chenxi/GXH-7364-2022; Liu, Zhiliang/ABZ-9726-2022; Chen, - Ziyi/CAH-5334-2022; Feng, Yali/MIN-3179-2025 -FU Jiangxi Provincial Natural Science Foundation of China [20204BCJL23052, - 20212ACB216013]; Nanchang Natural Science Foundation [129] -FX The author(s) declare financial support was received for the research, - authorship, and/or publication of this article. 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Immunol. -PD FEB 15 -PY 2024 -VL 15 -AR 1259788 -DI 10.3389/fimmu.2024.1259788 -PG 14 -WC Immunology -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Immunology -GA JN7W1 -UT WOS:001173922400001 -PM 38426106 -OA Green Published, gold -DA 2025-07-11 -ER - -PT J -AU Jimenez-Collado, D - Velasco-Sepúlveda, BH - Lee, A - Vera-Duarte, GR - Graue-Hernandez, EO - Navas, A -AF Jimenez-Collado, David - Velasco-Sepulveda, Braulio Hernan - Lee, Angel - Vera-Duarte, Guillermo Raul - Graue-Hernandez, Enrique O. - Navas, Alejandro -TI Corneal and Ocular Surface Contributions From Mexico: A Bibliometric - Analysis From 1913 to 2022 -SO CUREUS JOURNAL OF MEDICAL SCIENCE -LA English -DT Article -DE research; publication productivity; ophthalmology; bibliometrix; ocular - surface; bibliometric analysis -ID IN-SITU KERATOMILEUSIS -AB Objective: This study aimed to investigate all recorded corneal and ocular surface research by Mexican authors. Methods: The output data was extracted from SCOPUS to account for all publications regarding the corneal or ocular surface by Mexican authors. Data screening, extraction, and critical revision were performed by two of the authors to avoid duplication and ensure the authenticity of all papers. Performance analysis, science mapping, and network metrics were employed to retrieve trends in publication. Results: A total of 1,091 indexed journal documents by 3965 authors were retrieved, covering the period the period from 1919 to 2022. In performance analysis, the document types included 881 articles, 20 book chapters, 17 conference papers, three editorials, 37 letters to the editor, nine notes, and 123 reviews. A total of 3,965 contributing authors made 6,081 author appearances. In terms of total citations per country, Mexican authors received a total of 7,087 citations, with an average article citation of 8.76 per author. Conclusion: This bibliometric analysis highlights impactful research contributions to corneal and ocular surface research from Mexican authors, identifies influential authors and institutions, and also emphasizes the need for increased interaction in the international arena. -C1 [Jimenez-Collado, David] Inst Ophthalmol Conde Valenciana, Ophthalmol, Mexico City, Mexico. - [Velasco-Sepulveda, Braulio Hernan; Vera-Duarte, Guillermo Raul; Graue-Hernandez, Enrique O.; Navas, Alejandro] Inst Ophthalmol Conde Valenciana, Cornea, Mexico City, Mexico. - [Lee, Angel] Natl Inst Neurol & Neurosurg Manuel Velasco Suarez, Neurol Endovasc Therapy, Mexico City, Mexico. -RP Navas, A (corresponding author), Inst Ophthalmol Conde Valenciana, Cornea, Mexico City, Mexico. -EM dr.alejandro.navas@gmail.com -RI Jimenez-Collado, David/AAI-1796-2020; Velasco, Braulio/AAX-8366-2020; R. - Vera-Duarte, Guillermo/LMP-9081-2024; Navas, Alejandro/JBJ-5864-2023 -FX Conflicts of interest: In compliance with the ICMJE uniform disclosure - form, all authors declare the following: Payment/services info: All - authors have declared that no financial support was received from any - organization for the submitted work. Financial relationships: All - authors have declared that they have no financial relationships at - present or within the previous three years with any organizations that - might have an interest in the submitted work. Other relationships: All - authors have declared that there are no other relationships or - activities that could appear to have influenced the submitted work. -CR Aispuro GP, 2023, HEALTHCARE-BASEL, V11, DOI 10.3390/healthcare11121725 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - CaceresRios H, 1996, PEDIATR DERMATOL, V13, P105 - Lira RPC, 2013, ARQ BRAS OFTALMOL, V76, P26, DOI 10.1590/S0004-27492013000100008 - Chayet AS, 1998, OPHTHALMOLOGY, V105, P1194, DOI 10.1016/S0161-6420(98)97020-8 - Costagliola C, 2014, BIOMED RES INT, V2014, DOI 10.1155/2014/203868 - Diéguez-Campa CE, 2021, ARCH CARDIOL MEX, V91, P1, DOI [10.24875/ACM.20000370, 10.24875/acm.20000370] - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Elango B., 2012, International Journal of Information Dissemination and Technology, V2, P166 - Galván LC, 2018, ARQ BRAS OFTALMOL, V81, P24, DOI 10.5935/0004-2749.20180007 - Ventura AGGD, 2008, ARQ BRAS OFTALMOL, V71, P711, DOI 10.1590/S0004-27492008000500019 - Hartl FU, 2002, SCIENCE, V295, P1852, DOI 10.1126/science.1068408 - Hashemi H, 2018, J CURR OPHTHALMOL, V30, P3, DOI 10.1016/j.joco.2017.08.009 - Hefler L, 1999, LANCET, V353, P1856, DOI 10.1016/S0140-6736(99)01278-7 - Kauffmann T, 1997, GER J OPHTHALMOL, V5, P508 - Milia MF, 2023, QUANT SCI STUD, V4, P262, DOI 10.1162/qss_a_00239 - Muccioli Cristina, 2006, Arq. 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International frameworks, the 2030 Agenda for Sustainable Development, and Ocean Decade point out the significance of marine areas for achieving sustainable growth. This study conducts a bibliometric analysis of RS over marine areas for sustainable development to identify key contributors, collaboration networks, and evolving research themes from the beginning of the 21st century until last year. Using the Web of Science Core Collection database, 499 relevant articles published between 2000 and 2023 were identified. The bibliometric analysis showed a significant increase in scientific productivity related to the field. On an international level, China emerges as the most productive country, but international collaboration has played a crucial role, with 36.87% of articles resulting from international co-authorship, pointing to the global nature of research in this field. RS technology has continuously evolved from airborne sensors to the augmentation of Earth Observation missions. Our findings reveal a shift towards automated analysis and processing of RS data using machine learning techniques to integrate large datasets and develop robust scientific solutions. -C1 [Vrdoljak, Ljerka] Hydrog Inst Republ Croatia, Split 21000, Croatia. - [Racetin, Ivana] Univ Split, Fac Civil Engn Architecture & Geodesy, Split 21000, Croatia. - [Zrinjski, Mladen] Univ Zagreb, Fac Geodesy, Zagreb 10000, Croatia. -C3 University of Split; University of Zagreb -RP Vrdoljak, L (corresponding author), Hydrog Inst Republ Croatia, Split 21000, Croatia. -EM ljerka.vrdoljak@hhi.hr; ivana.racetin@gradst.hr; - mladen.zrinjski@geof.unizg.hr -RI vrdoljak, ljerka/HGF-1369-2022; Zrinjski, Mladen/AFI-8960-2022; Racetin, - Ivana/H-3610-2017 -OI Zrinjski, Mladen/0000-0003-0834-6009; Racetin, Ivana/0000-0003-0315-8826 -FU Croatian Government; European Union; [KK.01.1.1.02.0027] -FX This research is partially supported through project KK.01.1.1.02.0027, - a project co-financed by the Croatian Government and the European Union - through the European Regional Development Fund-the Competitiveness and - Cohesion Operational Program. -CR Addo KA, 2008, ISPRS J PHOTOGRAMM, V63, P543, DOI 10.1016/j.isprsjprs.2008.04.001 - Adger WN, 2006, GLOBAL ENVIRON CHANG, V16, P268, DOI 10.1016/j.gloenvcha.2006.02.006 - [Anonymous], 2023, Seabed - [Anonymous], Millennium Goals - [Anonymous], 1982, UN CONVENTION LAW SE - Araya-Lopez R, 2023, ECOL EVOL, V13, DOI 10.1002/ece3.10559 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Aschbacher J, 2012, REMOTE SENS ENVIRON, V120, P3, DOI 10.1016/j.rse.2011.08.028 - Bibliometrix, ABOUT US - Brammer H, 2014, CLIM RISK MANAG, V1, P51, DOI 10.1016/j.crm.2013.10.001 - Carpenter CR, 2014, ACAD EMERG MED, V21, P1160, DOI 10.1111/acem.12482 - Carr ME, 2001, DEEP-SEA RES PT II, V49, P59 - Chen BQ, 2017, ISPRS J PHOTOGRAMM, V131, P104, DOI 10.1016/j.isprsjprs.2017.07.011 - Chen CH, 2023, SUSTAINABILITY-BASEL, V15, DOI 10.3390/su151814031 - Chen GL, 2023, REMOTE SENS-BASEL, V15, DOI 10.3390/rs15194695 - Contarinis S, 2020, J MAR SCI ENG, V8, DOI 10.3390/jmse8080564 - Cullen J.J., 2001, Encyclopedia of the Ocean Sciences, P2277, DOI DOI 10.1006/RWOS.2001.0203 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Ekmen O, 2024, EGYPT J REMOTE SENS, V27, P329, DOI 10.1016/j.ejrs.2024.04.002 - EO4SDG, Earth Observations in Service of the 2030 Agenda for Sustainable Development. 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This study aims to provide a comprehensive summary of municipal wastewater research in Europe in the 2010s in the form of bibliometric analysis. The work was based on the Science Citation Index Expanded (Web of Science) and carried out using the R-package bibliometrix for bibliometric data analysis and the software VOSviewer for science mapping. Analysing a dataset of 5645 publications, we identified the most influential journals, countries, authors, institutions, and publications, and mapped the co-authorship and keyword co-occurrence networks. Spain had produced the most publications while Switzerland had the highest average citations per publication. China was the most collaborative country from outside of Europe. Analysis of the most cited articles revealed the popularity of micropollutant removal in European municipal wastewater research. The keyword analysis visualized a paradigm shift from pollutant removal towards resource recovery and circular economy. We found that current challenges of resource recovery from municipal wastewater come from both technical and non-technical (e.g., environmental, economic, and social) aspects. We also discussed future research opportunities that can tackle these challenges. -C1 [Marcal, Juliana; Bishop, Toby; Hofman, Jan; Shen, Junjie] Univ Bath, Dept Chem Engn, Bath BA2 7AY, Avon, England. - [Marcal, Juliana; Hofman, Jan; Shen, Junjie] Univ Bath, Water Innovat & Res Ctr WIRC, Bath BA2 7AY, Avon, England. - [Shen, Junjie] Univ Bath, Ctr Adv Separat Engn CASE, Bath BA2 7AY, Avon, England. - [Hofman, Jan] KWR Water Res Inst, POB 1072, NL-3430 BB Nieuwegein, Netherlands. -C3 University of Bath; University of Bath; University of Bath -RP Shen, JJ (corresponding author), Univ Bath, Dept Chem Engn, Bath BA2 7AY, Avon, England. -EM J.Shen@bath.ac.uk -RI ; Shen, Junjie/ABB-1005-2020; Hofman, Jan/U-6342-2019 -OI Bishop, Toby/0000-0002-8539-7945; Shen, Junjie/0000-0002-9837-9252; - Hofman, Jan/0000-0002-5982-603X; Marcal, Juliana/0000-0002-6843-8469 -FU Water Informatics Science and Engineering (WISE) Centre for Doctoral - Training (CDT) - UK Engineering and Physical Sciences Research Council - (EPSRC) [EP/L016214/1]; Royal Academy of Engineering [RF_201718_17145] -FX Juliana Marcal is supported by a PhD studentship from the Water - Informatics Science and Engineering (WISE) Centre for Doctoral Training - (CDT), funded by the UK Engineering and Physical Sciences Research - Council (EPSRC), Grant No. EP/L016214/1. The authors acknowledge Prof. - Mark van Loosdrecht (Delft University of Technology) for providing - valuable comments. 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Zheng TL, 2015, SCIENTOMETRICS, V105, P863, DOI 10.1007/s11192-015-1736-x -NR 81 -TC 36 -Z9 38 -U1 6 -U2 109 -PU PERGAMON-ELSEVIER SCIENCE LTD -PI OXFORD -PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND -SN 0045-6535 -EI 1879-1298 -J9 CHEMOSPHERE -JI Chemosphere -PD DEC -PY 2021 -VL 284 -AR 131267 -DI 10.1016/j.chemosphere.2021.131267 -EA JUL 2021 -PG 11 -WC Environmental Sciences -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Environmental Sciences & Ecology -GA WC7WP -UT WOS:000704464800002 -PM 34217935 -OA Green Submitted -DA 2025-07-11 -ER - -PT J -AU Srivastava, P - Bano, S -AF Srivastava, Prakhar - Bano, Samina -TI Mapping the landscape of cross-group friendship research: a bibliometric - review -SO CURRENT PSYCHOLOGY -LA English -DT Article -DE Cross-group friendship; Intergroup contact; Bibliometric analysis; - Contact theory -ID INTERGROUP CONTACT; EXTENDED CONTACT; ETHNIC FRIENDSHIPS; MEDIATING - ROLE; OUTGROUP ATTITUDES; NORTHERN-IRELAND; PREJUDICE; ANXIETY; - ASSOCIATION; ADOLESCENTS -AB Cross-group friendships play a crucial role in reducing prejudice and promoting social inclusion. While previous reviews have advanced our understanding using narrative or meta-analytic methods, they may not capture the full breadth of the research landscape. To address this limitation and provide a comprehensive mapping of the field, our review employs bibliometric analysis. We examined 323 scholarly works from the Scopus database (1961-2023) using Vosviewer and R-bibliometrix. Through performance analysis and science mapping, our study reveals the field's evolution, identifying key contributors, leading institutions, and influential journals. Co-citation analysis uncovers three main thematic clusters: the Contact Hypothesis, Dynamics and Impact of Cross-Group Friendships, and Direct and Extended Cross-Group Friendships. Additionally, bibliographic coupling analysis identifies emerging themes, including interethnic friendships among children, cross-group friendships as catalysts for societal change, and advances in intergroup contact theory. This comprehensive mapping complements existing reviews by offering a broader perspective on the field's structure and evolution. The insights gained from this review could potentially guide future research directions and inform policy and intervention strategies aimed at mitigating prejudice and promoting social cohesion. 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Psychol. -PD MAR -PY 2025 -VL 44 -IS 5 -BP 4055 -EP 4071 -DI 10.1007/s12144-025-07466-y -EA FEB 2025 -PG 17 -WC Psychology, Multidisciplinary -WE Social Science Citation Index (SSCI) -SC Psychology -GA 1XZ5B -UT WOS:001412697500001 -DA 2025-07-11 -ER - -PT J -AU Monteagudo-Fernández, J - Gómez-Carrasco, CJ - Chaparro-Sainz, A -AF Monteagudo-Fernandez, Jose - Gomez-Carrasco, Cosme J. - Chaparro-Sainz, Alvaro -TI Heritage Education and Research in Museums. Conceptual, Intellectual and - Social Structure within a Knowledge Domain (2000-2019) -SO SUSTAINABILITY -LA English -DT Article -DE bibliometric analysis; heritage education; museum research; research - review; science mapping -ID CULTURAL-HERITAGE; NETWORK ANALYSIS; TECHNOLOGY; IDENTITY; HISTORY; - SCHOOL; COLLABORATION; PERFORMANCE; EXHIBITION; BUILDINGS -AB Heritage and museums have constituted two fundamental axes of heritage education research in recent decades. This can be defined as the pedagogical process in which people can learn about heritage assets in formal or informal learning contexts. Museums, as centres of reference in informal education, are in constant and fluid contact with schools and produce different and varied didactic materials related to heritage. This paper provides results concerning the development and shaping of the knowledge domain known as heritage education between 2000 and 2019 on the Web of Science (WoS). To this end, different techniques and tools have been used: R-package Bibliometrix and VOSviewer. This analysis has identified five clusters with the topics underpinning heritage education as a specific field of knowledge. Our inquiry has highlighted the fact that there has been an increase in production regarding research topics associated with heritage education and museums in this period, particularly between 2015 and 2019. The inclusion of ESCI journals has led to a greater visibility of WoS-indexed academic production in some countries. Finally, the concepts "heritage", "museum" and "education" are the axes around which the research paradigms related to heritage education research seem to have been developed. -C1 [Monteagudo-Fernandez, Jose; Gomez-Carrasco, Cosme J.] Univ Murcia, Dept Math & Social Sci Educ, Murcia 30100, Spain. - [Chaparro-Sainz, Alvaro] Univ Almeria, Dept Educ, Almeria 04120, Spain. -C3 University of Murcia; Universidad de Almeria -RP Monteagudo-Fernández, J (corresponding author), Univ Murcia, Dept Math & Social Sci Educ, Murcia 30100, Spain. -EM jose.monteagudo@um.es; cjgomez@um.es; alvarocs@ual.es -RI Gomez, Cosme/M-5667-2014; Chaparro Sainz, Alvaro/M-7768-2015; CHAPARRO - SAINZ, ALVARO/ABE-4155-2020; Carrasco, Cosme/M-5667-2014; - Monteagudo-Fernández, José/S-6311-2016 -OI Gomez, Cosme/0000-0002-9272-5177; Monteagudo-Fernandez, - Jose/0000-0003-2680-7622; Chaparro Sainz, Alvaro/0000-0002-4118-9394; -FU Spanish Ministry of Science, Innovation and Universities - [PGC2018-094491-B-C33]; Fundacion Seneca [20638/JLI/18] -FX This work was supported by the Spanish Ministry of Science, Innovation - and Universities under Grant number PGC2018-094491-B-C33 and the - Fundacion Seneca under Grant number 20638/JLI/18. -CR Abbasi A, 2011, J INFORMETR, V5, P594, DOI 10.1016/j.joi.2011.05.007 - Altintas I N., 2020, International Journal of Evaluation and Research in Education, V9, P120, DOI DOI 10.11591/IJERE.V9I1.20380 - Andersen MF, 2020, J MUS EDUC, V45, P200, DOI 10.1080/10598650.2020.1744238 - Anderson S, 2018, MUS MANAGE CURATOR, V33, P320, DOI 10.1080/09647775.2018.1466351 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Ascenzi A, 2021, PAEDAGOG HIST, V57, P419, DOI 10.1080/00309230.2019.1660387 - Brouard MA, 2015, EDUC SIGLO XXI, V33, P55, DOI 10.6018/j/222501 - Ashton Paul., 2019, WHAT IS PUBLIC HIST, DOI DOI 10.5040/9781350033306 - Bardavio A., 2003, Objetos en el tiempo. 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In this paper, we provide a comprehensive bibliometric analysis to better understand the evolution of Artificial Intelligence in Renewable Energy (AI&RE) research from 2006 to 2022. This study is performed based on the Web of Science Core Collection Database, and a dataset of 469 publications have been retrieved. This paper uses VOS viewer, CiteSpace, and Bibliometrix to perform bibliometric analysis and science mapping. The analysis results show that China is the most productive and influential country/region, with the widest range of collaborative partners. The study reveals that AI-related technologies can effectively solve issues related to integrating renewable energy with power system, such as solar and wind forecasting, power system frequency analysis and control, and transient stability assessment. In addition, future research trends are discussed. This paper helps scholars to understand the evolution of AI&RE research from a bibliometric perspective and inspires them to think about the field through multiple aspects. (c) 2022 The Author(s). Published by Elsevier Ltd. 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-PT J -AU San-Juan-Heras, R - Gabriel, JL - Delgado, MM - Alvarez, S - Martinez, S -AF San-Juan-Heras, Raul - Gabriel, Jose L. - Delgado, Maria M. - Alvarez, Sergio - Martinez, Sara -TI Scientometric analysis of cover crop management: Trends, networks, and - future directions -SO EUROPEAN JOURNAL OF AGRONOMY -LA English -DT Article -DE Science mapping; Bibliometric analysis; Crops; Agriculture; VOSviewer -ID TILLAGE; SOIL -AB This research paper presents a comprehensive scientometric analysis of English articles from the Scopus database regarding the topic of cover crop management from 1956 to March 2024. Through the analysis of the annual production trend, total production, a co-occurrence network of keywords, co-authorship networks, and co- citation networks, the data was mapped and visualized using VOSviewer and Bibliometrix software. There was an exponential increase in publications from 1991 onwards. The predominant subject was Agricultural and Biological Sciences and the most relevant journals, authors, and documents were related to this topic. Additionally, the most productive country was the United States, but in terms of article production per surface area, other countries, such as Switzerland and The Netherlands, evidence the great weight of cover crop management in these countries. The identified research topics were related to the application of different crops as cover crops and the effects on different cultivars, also soil quality improvement, and fertilization and nutrient efficiency. An emerging research topic was found to be the usefulness of cover crops as effective tools for climate change adaptation and mitigation strategies in agriculture. Future research in the field of cover crop management could be directed towards climate-adaptive cover crop species and varieties, the use of technological innovations for cover crop monitoring, and management and analysis of the economic and social impacts of cover crop adoption. -C1 [San-Juan-Heras, Raul; Gabriel, Jose L.; Delgado, Maria M.] Inst Nacl Invest n & Tecnol Agr & Alimentaria INIA, CSIC, Environm & Agron Dept, Ctra Coruna Km 7,5, Madrid 28040, Spain. - [San-Juan-Heras, Raul] Univ Politecn Madrid, Escuela Tecnicacn Suerior Ingn Agron Alimentaria &, Ave Puerta Hierro 2, Madrid 28040, Spain. - [Gabriel, Jose L.] UPM, Ctr Estudios & Invest Gest Riesgos Agr & Medioambi, Madrid 28040, Spain. - [Alvarez, Sergio; Martinez, Sara] Univ Politecn Madrid, Dept Ingn & Morfol Terreno, Escuela Tecnicacn Super Ingn Caminos Canales & Pue, Calle Prof Aranguren 3, Madrid 28040, Spain. -C3 Consejo Superior de Investigaciones Cientificas (CSIC); Universidad - Politecnica de Madrid; Universidad Politecnica de Madrid; Universidad - Politecnica de Madrid -RP Gabriel, JL (corresponding author), INIA CSIC, Dept Medio Ambiente Agron, Ctra Coruna Km 7-5, Madrid 28040, Spain. -EM gabriel.jose@inia.csic.es -RI San-Juan-Heras, Raúl/HCI-7358-2022; Gabriel, Jose Luis/B-9605-2013; - gabriel, jose/B-9605-2013 -OI Gabriel, Jose Luis/0000-0002-5508-4120; -FU MCIN/AEI; PTI AGRIAMBIO (MAPA-CSIC agreement); [PID2021-124041OB-C21] -FX This study was supported by the project PID2021-124041OB-C21. - RESUENA-Legumes, funded by MCIN/AEI/10.13039/501100011033/, and by PTI - AGRIAMBIO (MAPA-CSIC agreement) . 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Agron. -PD NOV -PY 2024 -VL 161 -AR 127355 -DI 10.1016/j.eja.2024.127355 -EA SEP 2024 -PG 11 -WC Agronomy -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Agriculture -GA H0D2E -UT WOS:001320231200001 -OA hybrid -DA 2025-07-11 -ER - -PT J -AU Norouzi, M - Chàfer, M - Cabeza, LF - Jiménez, L - Boer, D -AF Norouzi, Masoud - Chafer, Marta - Cabeza, Luisa F. - Jimenez, Laureano - Boer, Dieter -TI Circular economy in the building and construction sector: A scientific - evolution analysis -SO JOURNAL OF BUILDING ENGINEERING -LA English -DT Article -DE Circular economy; Building; Construction sector; Science mapping; - Bibliometric analysis; Sustainable development -ID BIBLIOMETRIC ANALYSIS; GOOGLE SCHOLAR; SCIENTOMETRIC ANALYSIS; - INDUSTRIAL SYMBIOSIS; ENERGY-CONSUMPTION; BIG-DATA; SUSTAINABILITY; - MANAGEMENT; SCIENCE; FUTURE -AB The building industry is responsible for considerable environmental impacts due to its consumption of resources and energy, and the production of wastes. Circular Economy (CE), a new paradigm can significantly improve the sustainability of this sector. This paper performs a quantitative scientific evolution analysis of the application of CE in the building sector to detect new trends and highlight the evolvement of this research topic. Around 7000 documents published 2005 to 2020 at Web of Science and Scopus were collected and analyzed. The bibliometric indicators, network citation, and multivariate statistical analysis were obtained using Bibliometrix R-package and VOSviewer. The co-occurrence analysis showed five keyword-clusters, in which the three main ones are: (i) energy and energy efficiency in buildings; (ii) recycling, waste management and alternative construction materials; (iii) sustainable development. The analysis showed that researchers pay close attention to "sustainability", "energy efficiency", "life cycle assessment", "renewable energy", and "recycling" in the past five years. This paper highlights that (i) the development and use of alternative construction materials; (ii) the development of circular business models; (iii) smart cities, Industry 4.0 and their relations with CE, are the current research hotspots that may be considered as potential future research topics. -C1 [Norouzi, Masoud; Jimenez, Laureano] Univ Rovira & Virgili, Dept Engn Quim, Av Paisos Catalans 26, Tarragona 43007, Spain. - [Chafer, Marta; Cabeza, Luisa F.] Univ Lleida, GREiA Res Ctr, Pere Cabrera S-N, Lleida 25001, Spain. - [Chafer, Marta] Univ Perugia, CIRIAF Interuniv Res Ctr, Via G Duranti 67, I-06125 Perugia, Italy. - [Boer, Dieter] Univ Rovira & Virgili, Dept Engn Mecan, Av Paisos Catalans 26, Tarragona 43007, Spain. -C3 Universitat Rovira i Virgili; Universitat de Lleida; University of - Perugia; Universitat Rovira i Virgili -RP Boer, D (corresponding author), Univ Rovira & Virgili, Dept Engn Mecan, Av Paisos Catalans 26, Tarragona 43007, Spain. -EM masoud.norouzi@urv.cat; marta.chafer@diei.udl.cat; lcabeza@diei.udl.cat; - laureano.jimenez@urv.cat; dieter.boer@urv.cat -RI Jiménez Esteller, Laureano/F-6782-2011; Boer, Dieter/K-3162-2014; - Cabeza, Luisa F./B-4587-2013; Norouzi, Masoud/ACN-7197-2022 -OI Norouzi, Masoud/0000-0003-2943-5174; -FU Spanish Ministry of Economy and Competitiveness [RTI2018-093849-B-C33, - RTI2018-093849-B-C31, CTQ2016-77968-C3-1-P]; Catalan Government - [2017-SGR-1409, 2017-SGR-1537, 2019 FI-B-00762]; Ministerio de Ciencia, - Innovacion y Universidades-Agencia Estatal de Investigacion (AEI) - [RED2018-102431-T]; ICREA -FX The authors would like to acknowledge financial support from the Spanish - Ministry of Economy and Competitiveness RTI2018-093849-B-C33 - (MCIU/AEI/FEDER, UE) , RTI2018-093849-B-C31 (MCIU/AEI/FEDER, UE) and - CTQ2016-77968-C3-1-P (MINECO/FEDER) and thank the Catalan Government - (2017-SGR-1409, 2017-SGR-1537, and 2019 FI-B-00762) . 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Build. Eng. -PD DEC -PY 2021 -VL 44 -AR 102704 -DI 10.1016/j.jobe.2021.102704 -EA MAY 2021 -PG 18 -WC Construction & Building Technology; Engineering, Civil -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Construction & Building Technology; Engineering -GA UW3IC -UT WOS:000700053000003 -OA Green Published, hybrid -HC Y -HP N -DA 2025-07-11 -ER - -PT J -AU Razia, S - Ah, SHBA -AF Razia, Sultana - Ah, Siti Hajar Binti Abu Bakar -TI Panoramic Mapping of Urban Social Sustainability: A 35-Year Bibliometric - and Visualization Analysis -SO JOURNAL OF REGIONAL AND CITY PLANNING -LA English -DT Article -DE Bibliometric; Biblioshiny; Mapping Analysis; Social Sustainability; - Sustainable Urban Development; VOSviewer -ID SCIENCE; ARTICLES; INDEX; FORM -AB In recent years, ensuring social sustainability has been a global concern for sustainable urban development in both the academic arena and sustainability science. Many studies have been conducted in this area, but a bibliometric analysis has not yet been done previously. This study identified research streams and research hotspots in the urban social sustainability field based on a bibliometric analysis from 1985 to 2020, involving 1,623 documents from the Web of Science database. We used two software packages, Bibliometrix (Biblioshiny) and VOSviewer, for performance and science mapping analysis. The result showed that this research field is growing fast in multiple disciplines. In the publication trend analysis, we found significant changes since 2015. Analysis of leading countries and institutions revealed that developed countries are performing better than developing countries in producing publications on urban social sustainability. In the content analysis, we selected 214 documents and found that the survey method was the most used. Additionally, we found that 13.08 percent of papers (28 out of 214) used as many as 21 different theories, where 'stakeholder theory,' 'planning theory,' 'theory of urbanism as a way of life,' and 'theory of good city form' were significantly used. The findings of this study can assist researchers and practitioners by providing valuable insights into the research area of urban social sustainability. -C1 [Razia, Sultana; Ah, Siti Hajar Binti Abu Bakar] Univ Malaya, Fac Arts & Social Sci, Dept Social Adm & Justice, Kuala Lumpur, Malaysia. -C3 Universiti Malaya -RP Ah, SHBA (corresponding author), Univ Malaya, Fac Arts & Social Sci, Dept Social Adm & Justice, Kuala Lumpur, Malaysia. -EM ava180065@siswa.um.edu.my; shajar@um.edu.my -RI ; ABU BAKAR AH, SITI HAJAR/B-9791-2010; Razia, Sultana/GYD-3479-2022 -OI Razia, Dr. Sultana/0000-0002-3636-8718; -CR Ahvenniemi H, 2017, CITIES, V60, P234, DOI 10.1016/j.cities.2016.09.009 - Akan MÖA, 2018, EUR J SUSTAIN DEV, V7, P412, DOI 10.14207/ejsd.2018.v7n1p363 - Ali HH, 2019, INT J URBAN SUSTAIN, V11, P203, DOI 10.1080/19463138.2019.1590367 - Ameen R., 2017, FRAMEWORK SUSTAINABI - [Anonymous], 2003, SUST COMM BUILD FUT - [Anonymous], 2020, WORLD EC SITUATION P, P163, DOI [DOI 10.18356/036ADE46-EN, 10.18356/ee1a3197-en, DOI 10.18356/EE1A3197-EN] - [Anonymous], 2006, INFLUENCE QUALITY BU - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Baffoe Gideon., 2015, Environmental Management and Sustainable Development, V4, P242, DOI DOI 10.5296/EMSD.V4I2.8399 - Biscaro C, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0099502 - Booth A, 2016, Systematic approaches to a successful literature review, V2nd - Bramley G., 2006, Sustainable Communities and Green Futures' track - Bramley G, 2009, ENVIRON PLANN A, V41, P2125, DOI 10.1068/a4184 - Burton E., 2006, Inclusive Urban Design: Streets For Life, DOI DOI 10.4324/9780080456454 - Chen LJ, 2017, INT J PROD ECON, V194, P73, DOI 10.1016/j.ijpe.2017.04.005 - Chiu RLH, 2002, SUSTAIN DEV, V10, P155, DOI 10.1002/sd.186 - Ciccullo F, 2018, J CLEAN PROD, V172, P2336, DOI 10.1016/j.jclepro.2017.11.176 - Clark V.L. 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Recent development in the banking industry is channelling the funds and participating in economic activities directly. Hence, academic researchers are gradually showing their concern on banking performance and its effect on economic growth. Therefore, this study aims to explore the academic researchers on this particular academic research article. By extracting data from the web of Science online database, this study employed the bibliometrix package (biblioshiny) in the'R'and VOSviewer tool to conduct performance and science mapping analyses. A total of 1308 research documents were analysed, and 36 documents were critically reviewed. The findings exhibited a recent growth in academic publications. Three major themes are mainly identified, efficiency measurement, corporate governance effect and impact on economic growth. Besides, the content analysis represents the most common analysis techniques used in the past studies, namely DEA and GMM. 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Bus. J. -PD DEC 14 -PY 2021 -VL 7 -IS 1 -AR 66 -DI 10.1186/s43093-021-00111-7 -PG 19 -WC Business -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA XO4UI -UT WOS:000730181800001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Ramanan, SS - George, AK - Chavan, SB - Kumar, S - Jayasubha, S -AF Ramanan, Suresh S. - George, Alex K. - Chavan, S. B. - Kumar, Sudhir - Jayasubha, S. -TI Progress and future research trends on Santalum album: A - bibliometric and science mapping approach -SO INDUSTRIAL CROPS AND PRODUCTS -LA English -DT Article -DE Santalum album research trend; Indian sandalwood; Global status -ID VITRO PLANT-REGENERATION; SANDALWOOD; L.; GROWTH; PROVENANCES; - RESOURCES; LANGUAGE; ENGLISH; CHINA -AB Sandalwood (Santalum album) is woven into the culture and traditions of India for last 3000 years. However, India's dominance on the international sandalwood trade is waning. Other countries, specifically Australia are emerging as a big-mammoth player in sandalwood trade. Still, there is a high demand-supply gap for Indian Sandalwood. This offers opportunities for the countries to dominate the trade by upscaling sandalwood cultivation among farmers and various stakeholders. Considering the extent of research activity as a proxy to a country's attitude and approach towards the Santalum album, we used the theoretical framework of bibliometric studies to understand the current status of Indian sandalwood research globally. After 92 years of research (1928-2020), 374 scientific publications were listed in the Web of Science database for a single keyword search "Santalum album". Analysis of this metadata using the bibliometrix R-package revealed an annual growth of 5.25 per cent in scientific publications over the years. Lokta's law was found to be valid for Indian sandalwood research, indicating a possibility for increased research in the upcoming years which perfectly correlate with the increase in sandalwood prices. The analysis revealed a decadal shift in prominent researching countries. India dominated in terms of the number of scientific publications for the last two decades, followed by Australia during the decade I (2000-2010). However, China surpassed Australia in the current decade (2011-2020) in terms of research output. Further, more productive researchers were from China and Australia. The increased interest of Chinese researchers can have an impact on sandalwood market in the near possible future. SciMAT science mapping tool was used to map prominent researched areas over the 92 years and to uncover the future researchable areas. 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The objective of this study is to provide a comprehensive analysis of the advancements and trends in nanozymes for microbial theranostics research over the past decade through a detailed bibliometric approach. For this purpose, an effective search query was formulated, and relevant publications from 2013 to 2023 were collected from the Web of Science Core Collection database. Subsequently, the following softwares were employed for analysis: VOSviewer, the Bibliometrix R package, and GraphPad Prism 8.0.2. The findings revealed a statistically significant positive correlation (r = 0.993; p < 0.0001) between publications and citations, in addition to an important growth rate of scientific output of approximately 28.90%. China, India, and the USA were the most productive countries, whereas progress in low- and middle-income countries remained constrained. The Chinese Academy of Sciences was the most productive institution, and remarkably almost the top 10 productive authors were from China. 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Biochem. Biotechnol. -PD MAR -PY 2025 -VL 197 -IS 3 -BP 1923 -EP 1945 -DI 10.1007/s12010-024-05120-0 -EA DEC 2024 -PG 23 -WC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology -GA 0SG5F -UT WOS:001369440100001 -PM 39625609 -DA 2025-07-11 -ER - -PT C -AU Tassone, T - Franco, ER -AF Tassone, Tonia - Franco, E. Rubino -BE Vrontis, D - Weber, Y - Tsoukatos, E -TI A "BIBLIOMETRIX" REVIEW OF MANAGEMENT CONTROL -SO 13TH ANNUAL CONFERENCE OF THE EUROMED ACADEMY OF BUSINESS: BUSINESS - THEORY AND PRACTICE ACROSS INDUSTRIES AND MARKETS -SE EuroMed Academy of Business Conference Book of Proceedings -LA English -DT Proceedings Paper -CT 13th Annual Conference of the EuroMed-Academy-of-Business (EuroMed) - - Business Theory and Practice Across Industries and Markets -CY SEP 09-10, 2020 -CL ELECTR NETWORK -DE Management control; Management control system; Bibliometrics; Review; - Science mapping -ID CONTROL-SYSTEMS; EVOLUTION; FIELD -AB In recent years, researchers, academics, practitioners, and stakeholders have begun to question the causes of the gap between theory and practice in Management Control field due to the misalignments between the innovations brought by academics (Johnson and Kaplan, 1987) and the changing in the control needs that made management control's tools obsolete (Nixon and Burns, 2005). The need of new frameworks more adherent to current conditions has become pressing (Otley, Broadbent and Berry, 1995; Langfield-smith, 1997; Nixon and Burns, 2005; Malmi and Brown, 2008; van Helden and Reichard, 2019;Chenhall, 2003). Therefore, the huge proliferation of theoretical contributions carried to an overwhelming mole of theoretical conceptualisations that has led the management control literature to trickle through further different control-related fields (Anthony; 1965; Lowe, 1971; Ouchi, 1979; Flamholtz, 1979; Otley and Berry, 1980; Daft and Macintosh, 1984; Abernethy and Chua, 1996; Otley, 1999; Chenhall, 2003; Merchant and Van der Stede, 2007; Malmi and Brown, 2008; Ferreira and Otley 2005, 2009; Strau(sic) and Zecher, 2013) and to lose comprehensive homogeneity and coherence. According to Ramos-Rodrigue & Ruiz-Navarro (2004), "Once a scientific discipline has reached a certain degree of maturity, it is common practice for its scholars to turn their attention towards the literature generated by the scientific community and, treating it as a research topic in its own right, to conduct reviews of the literature with a view to assessing the general state of the art". On this premises, our purpose is to provide both an overview and detailed key findings in the management control's research. This could shed light on aspects related to the current fragmented literature and lead researchers to appreciating what has be done so far and what has to be done, taking their own reasonable conclusions.This work aims to contribute to research on Management Control by carrying out a bibliometric analysis of the extant Management control literature through common science mapping techniques. It provides a descriptive analysis of the relevant contributions and results of a science mapping study on the conceptual, intellectual and social structure of the Management Control knowledge. Thus, conceptualizations, sources of knowledge, and community networks are considered basic. Conceptual, intellectual, and social interrelationships have been intercepted, so that a reconstruction of the management control debates in terms of academic research production has been coped with. A further theoretical contribution has been given by the identification of the main themes orbiting this field. So that it is possible to obtain information about the impact that the Management Control research has had outside the specific research field panorama or consolidated communities. Hence, bibliometric techniques have been implemented, by using a package in the R environment. In order to perform our bibliometric analysis, we apply a standard science mapping workflow (Zupic and Cater, 2015; Cobo et al., 2011, 2014; Aria and Cuccurullo, 2017). The analysis follows a protocol that not only makes the process traceable (Liberati et al., 2009) and verifiable, but minimizes probable distortions (Tranfield, Denyer and Smart, 2003; Schmeisser, 2013; Durach, Kembro and Wieland, 2017). Analysis object is characterized by a sample of papers extracted from Scopus. - In order to ensure a high quality level of research, the extraction criterions include the exclusive inclusion of the main journals indexed according to the Academic Journal Guide 2018 published by the Chartered Association of Business School. -C1 [Tassone, Tonia; Franco, E. Rubino] Univ Calabria, DISCAG, Arcavacata Di Rende, CS, Italy. -C3 University of Calabria -RP Tassone, T (corresponding author), Univ Calabria, DISCAG, Arcavacata Di Rende, CS, Italy. -CR [Anonymous], 2005, MANAGE ACCOUNT RES, V16, P260, DOI DOI 10.1016/J.MAR.2005.07.001 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Chenhall RH, 2003, ACCOUNT ORG SOC, V28, P127, DOI 10.1016/S0361-3682(01)00027-7 - Cobo MJ, 2014, IEEE T INTELL TRANSP, V15, P901, DOI 10.1109/TITS.2013.2284756 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - DAFT RL, 1984, J MANAGE, V10, P43, DOI 10.1177/014920638401000105 - Durach CF, 2017, J SUPPLY CHAIN MANAG, V53, P67, DOI 10.1111/jscm.12145 - Ferreira A., 2005, SOCIAL SCI RES NETWO - Ferreira A, 2009, MANAGE ACCOUNT RES, V20, P263, DOI 10.1016/j.mar.2009.07.003 - Furrer O, 2008, INT J MANAG REV, V10, P1, DOI 10.1111/j.1468-2370.2007.00217.x - Galvagno M., 2016, QUAL QUANT METHODS L, V4, pXIII, DOI [10.3280/MC2017-004001, DOI 10.3280/MC2017-004001] - Johnson H.T., 1987, Relevance lost The rise and fall of management accounting - Langfield-smith K.I. 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A lexical title search was applied to get the corpus of the study - a total of 4,599 articles were extracted for data analysis and visualisation. Further, the data were analysed by using the data analytical tools, R-studio and VOSViewer.FindingsThe findings showed that the "publications" have substantially grown up during the timeline. The most productive phase (2018-2021) resulted in 47% of articles. The prominent sources were PLOS One and NeuroImage. The highest number of papers were contributed by Haddaway and Kumar. The most relevant countries were the USA and UK.Practical implicationsThe study is useful for researchers interested in the GL research domain. The study helps to understand the evolution of the GL to provide research support further in this area.Originality/valueThe present study provides a new orientation to the scholarly output of the GL. The study is rigorous and all-inclusive based on analytical operations like the research networks, collaboration and visualisation. 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Hi Tech -PD FEB 14 -PY 2024 -VL 42 -IS 1 -BP 309 -EP 330 -DI 10.1108/LHT-01-2022-0012 -EA DEC 2022 -PG 22 -WC Information Science & Library Science -WE Social Science Citation Index (SSCI) -SC Information Science & Library Science -GA HS2C0 -UT WOS:000899972300001 -DA 2025-07-11 -ER - -PT J -AU Pendse, MK - Nerlekar, VS - Darda, P -AF Pendse, Meenal Kaustubh - Nerlekar, Varsha Shriram - Darda, Pooja -TI A comprehensive look at Greenwashing from 1996 to 2021: a bibliometric - analysis -SO JOURNAL OF INDIAN BUSINESS RESEARCH -LA English -DT Review -DE Greenwashing; Non-sustainable practices; Sustainability; Bibliometric - analysis; Bibliometrix; Science mapping -ID ENVIRONMENTAL PERFORMANCE; GREEN; LEGITIMACY; TRUST; ANTECEDENTS; - DISCLOSURE; MANAGEMENT; SCIENCE; CLAIMS -AB Purpose This paper aims to see how scholarly research on Greenwashing practices and behaviour has progressed in the 21st century. There has been a lot of empirical, exploratory and conceptual work done on Green marketing, sustainable marketing and environmental marketing. However, there have been few attempts to produce a comprehensive scientific mapping of Greenwashing as a niche topic. As a result, the study's goal is to elicit research trends through knowledge structure synthesis. Design/methodology/approach A Bibliometric Analysis on the topic of Greenwashing practices was undertaken on 355 publications. For this, a scientific search strategy was run on the Scopus database for the period 1996-2021. The study was conducted using Biblioshiny, a Web-based application that is part of the Bibliometric package. Important journals, countries, authors, keywords and affiliations were found using the software's automated workflow and thematic evolution, citations, co-citations and social network analysis were performed. Findings The study indicated a gradual increase in the research related to Greenwashing practices. The findings show a relative concentration of more influential work in the said domain amongst a handful of research scholars. Many influential studies have occurred after 2007, and a rally is seen in the studies on Greenwashing till 2020. The authors can say that the rigour of research has started increasing since then. Geographic dispersion of the work has shown that the USA followed by the UK dominates the scholarly inquiry and these countries have major collaboration with European and Asian researchers. The 10 most productive countries were examined, and it was discovered that the USA contributed the majority of the publications, with the UK and China coming in second and third place, respectively, in terms of publication in the said sector. In addition to the domain's conceptual structure, the study exposes the domain's social and Intellectual structure. This brings up new possibilities for Greenwashing studies in the future. Research limitations/implications The present research is a Bibliometric analysis that is restricted to science mapping, and hence, limitations apply to the said studies. Researchers can use systematic literature review to build a robust conceptual foundation in the future. The Scopus database was used for this study because it has a greater number of high-quality journals in structured forms that are compatible with Bibliometrix software. Practical implications Greenwashing practices and behaviour, as well as their links to sustainability, are discussed in this paper. It highlights the most often stated challenges in the discipline and suggests possible research topics. It provides future scholars with information on this discipline's issues, contexts and collaboration opportunities. Social implications The current study can give further directions to the researchers for conducting rigorous research on Greenwashing behaviour and practices and will guide the policymakers to formulate policies in the field of non-sustainable activities, with Greenwashing being one of them. Originality/value A lot of work is done by the scientific community in Green marketing research, and a lot of literature is available on Green and Sustainable marketing practices. However, there is still a need felt for more extensive and rigorous research on the evolution of Greenwashing methods. - This study makes a significant addition in that it brings together the scattered literature in the field, focuses on important sources, authors and documents, and investigates Greenwashing techniques and behaviour, which is the other side of the sustainable practices coin. -C1 [Pendse, Meenal Kaustubh; Nerlekar, Varsha Shriram; Darda, Pooja] Dr Vishwanath Karad MIT World Peace Univ, Sch Management PG, Pune, Maharashtra, India. -C3 Dr. Vishwanath Karad MIT World Peace University -RP Pendse, MK (corresponding author), Dr Vishwanath Karad MIT World Peace Univ, Sch Management PG, Pune, Maharashtra, India. -EM meenal.pendse@mitwpu.edu.in -RI Pendse, Meenal/AEB-3294-2022; nerlekar, Varsha/ABF-4074-2022 -OI Nerlekar, Varsha/0000-0003-1185-8304; -CR [Anonymous], 2006, Multiple Correspondence Analysis and Related Methods, DOI DOI 10.1201/9781420011319 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bansal P, 2004, ACAD MANAGE J, V47, P93, DOI [10.2307/20159562, 10.5465/20159562] - Baum LM, 2012, ENVIRON COMMUN, V6, P423, DOI 10.1080/17524032.2012.724022 - Blome C, 2017, J CLEAN PROD, V152, P339, DOI 10.1016/j.jclepro.2017.03.052 - Bowen F, 2014, ORGAN ENVIRON, V27, P107, DOI 10.1177/1086026614537078 - Brécard D, 2017, J REGUL ECON, V51, P340, DOI 10.1007/s11149-017-9328-8 - Chen XL, 2019, BMC MED INFORM DECIS, V19, DOI 10.1186/s12911-019-0757-4 - Chen YS, 2013, J BUS ETHICS, V114, P489, DOI 10.1007/s10551-012-1360-0 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - Netto SVD, 2020, ENVIRON SCI EUR, V32, DOI 10.1186/s12302-020-0300-3 - de Vries G, 2015, CORP SOC RESP ENV MA, V22, P142, DOI 10.1002/csr.1327 - Della Corte V, 2019, SUSTAINABILITY-BASEL, V11, DOI 10.3390/su11216114 - Delmas MA, 2021, ECOL ECON, V183, DOI 10.1016/j.ecolecon.2021.106953 - Delmas MA, 2011, CALIF MANAGE REV, V54, P64, DOI 10.1525/cmr.2011.54.1.64 - Du XQ, 2015, J BUS ETHICS, V128, P547, DOI 10.1007/s10551-014-2122-y - Egghe L., 1990, Introduction to informetrics: Quantitative methods in library documentation and information science - Fahimnia B, 2015, INT J PROD ECON, V162, P101, DOI 10.1016/j.ijpe.2015.01.003 - Firth LB, 2020, J APPL ECOL, V57, P1762, DOI 10.1111/1365-2664.13683 - Forbes L. 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Indian Bus. Res. -PD MAR 3 -PY 2023 -VL 15 -IS 1 -SI SI -BP 157 -EP 186 -DI 10.1108/JIBR-04-2022-0115 -EA NOV 2022 -PG 30 -WC Business -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA 9L2OW -UT WOS:000879317600001 -DA 2025-07-11 -ER - -PT J -AU Anas, M - Khan, MN - Uddin, SMF -AF Anas, Mohammad - Khan, Mohammed Naved - Uddin, S. M. Fatah -TI Mapping the concept of online purchase experience: a review and - bibliometric analysis -SO INTERNATIONAL JOURNAL OF QUALITY AND SERVICE SCIENCES -LA English -DT Review -DE Online purchase experience; Literature review; Bibliometrics; Consumer - behaviour -ID CUSTOMER EXPERIENCE; SHOPPING EXPERIENCE; TRUST; ENVIRONMENTS; - TECHNOLOGY; BEHAVIOR; INFORMATION; CONSUMPTION; MANAGEMENT; COCITATION -AB Purpose - Modern businesses strategically focus on improving the online purchase experience (OPE) of customers to acquire a long-term competitive edge. However, the intellectual knowledge structure of OPE research remains uncharted, necessitating further investigation. This study aims to provide a concise synthesis of the evolution, trends and advancements of consumers' OPE research using bibliometrics. - Design/methodology/approach - Firstly, the authors inventorised the relevant OPE literature, and then the bibliometric trends and the domain's performance (top articles, outlets and authors) were analysed and illustrated through tables and narratives. Secondly, science mapping tools (such as co-occurrence) and visualisation strategy were deployed to pinpoint relevant OPE research themes and highlight the domain's intellectual structure. - Findings - The most significant findings concern the most prolific authors, outlets, most cited articles and five thematic clusters forming the ground for potential future research paths. Also, these thematic clusters depicted the intellectual knowledge structure that emerged from the OPE research domain. - Research limitations/implications - This review may be helpful for future academic researchers to identify future research paths in the domain and practitioners to help make policy decisions while formulating and articulating their marketing strategy. - Originality/value - Deploying the VOSviewer and Bibliometrix-R software together, this review is most likely the first attempt to the best of the authors' knowledge to provide a thorough bibliometric synthesis of the OPE research domain. -C1 [Anas, Mohammad; Khan, Mohammed Naved] Aligarh Muslim Univ, Dept Business Adm, Aligarh, India. - [Uddin, S. M. 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J. Qual. Serv. Sci. -PD AUG 7 -PY 2023 -VL 15 -IS 2 -BP 168 -EP 189 -DI 10.1108/IJQSS-07-2022-0077 -EA JUN 2023 -PG 22 -WC Management -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA O3LG5 -UT WOS:001000065400001 -DA 2025-07-11 -ER - -PT J -AU Syahid, A - Aghayani, B -AF Syahid, Abdul - Aghayani, Behnam -TI ZOLTÁN DÖRNYEI'S IMPACT ON LANGUAGE ACQUISITION AND EDUCATION STUDIES: A - SCOPUS-BASED BIBLIOMETRIC STUDY (1991-2023) -SO LLT JOURNAL-A JOURNAL ON LANGUAGE AND LANGUAGE TEACHING -LA English -DT Article -DE motivation language theory; publication and citation pattern; science - mapping; scientometric portrait; Zolt & aacute;n D & ouml;rnyei -ID MOTIVATION; ENJOYMENT; LEARNERS; DYNAMICS; ANXIETY -AB Previous literature reviews and bibliometric studies have paid much attention to the scientific outputs of Zolt & aacute;n D & ouml;rnyei, a leading figure in the field of second language acquisition and education. However, little attention has been paid to his scholarly impact. This study aims to analyze all publications citing his 87 works in Scopus. Bibliometrix, a comprehensive bibliometric tool, was run to analyze 7,621 documents published in 1,970 sources by 9,226 authors of 2,652 institutions across 99 countries between 1991 and 2023. The analyses include the publication trend, research contributors, including authors, document elements including keywords, collaboration networks of research contributors, shared references, and frequently used keywords. Although most documents were written in English in the fields of social sciences as well as arts and humanities, his impact could be observed across other subject areas and languages. Further discussion elaborated on four major themes of the publications, including motivation, L2 motivational self-system, language learning, and positive psychology. This study could provide researchers and educators with valuable insights into understanding and improving language acquisition processes based on D & ouml;rnyei's incalculable intel lectual contribution. As this study focused on quantitative citation analysis, future research on how D & ouml;rnyei's works were cited could provide deeper insights into his impact. -C1 [Syahid, Abdul] Inst Agama Islam Negeri Palangka Raya, Palangkaraya, Indonesia. -RP Syahid, A (corresponding author), Inst Agama Islam Negeri Palangka Raya, Palangkaraya, Indonesia. -EM abdul.syahid@iain-palangkaraya.ac.id; aghayani.behnam@gmail.com -RI Aghayani, Behnam/U-9868-2018; Syahid, Abdul/AAW-6578-2020 -OI Syahid, Abdul/0000-0001-7284-4665 -CR Ajzen I., 1988, Attitudes, Personality, and Behavior - Al-Hoorie AH, 2022, LANG LEARN, V72, P896, DOI 10.1111/lang.12519 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Chen CM, 2018, SCIENTOMETRICS, V114, P489, DOI 10.1007/s11192-017-2594-5 - Claro J, 2020, PSYCHOL LANG LEARN T, V3, P233 - de Bot K., 2015, A history of applied linguistics: From 1980 to the present, DOI [10.4324/9781315743769, DOI 10.4324/9781315743769] - Delpeuch Antonin, 2023, Zenodo, DOI 10.5281/ZENODO.8153462 - Dewaele JM, 2020, STUD SECOND LANG LE, V10, P45, DOI 10.14746/ssllt.2020.10.1.3 - Dewaele JM, 2016, SECOND LANG ACQUIS, V97, P215 - Dewaele JM, 2014, STUD SECOND LANG LE, V4, P237, DOI 10.14746/ssllt.2014.4.2.5 - Dörnyei Z, 2009, SECOND LANG ACQUIS, P9 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - DORNYEI Z, 1994, MOD LANG J, V78, P273, DOI 10.2307/330107 - Dörnyei Z, 2002, APPL LINGUIST, V23, P421, DOI 10.1093/applin/23.4.421 - DORNYEI Z, 1990, LANG LEARN, V40, P45, DOI 10.1111/j.1467-1770.1990.tb00954.x - Dornyei Z., 1998, Language Teaching, V32, P117, DOI [10.1017/S026144480001315X, DOI 10.1017/S026144480001315X] - Dornyei Z., 2023, Questionnaires in Second Language Research: Construction, Administration, and Processing, VThird - Dornyei Z., 2006, Motivation, language attitudes and globalization: A Hungarian perspective, DOI DOI 10.21832/9781853598876 - Dornyei Z., 2020, Smart Biosensors in Medical Care, pxix, DOI DOI 10.1016/B978-0-12-820781-9.00017-6 - Dornyei Z., 2016, Becoming and being an applied linguist, P119, DOI DOI 10.1075/Z.203.05DOR - Dornyei Z., 2005, The Psychology of the Language Learner: Individual Differences in Second Language Acquisition, DOI DOI 10.1177/13621688070110040802 - Ellis R, 1994, 2 LANGUAGE ACQUISITI - Ellis R., 2008, STUDY 2 LANGUAGE ACQ - Elsevier, 2023, Content-How Scopus works - Flynn CJ, 2016, J MULTILING MULTICUL, V37, P371, DOI 10.1080/01434632.2015.1072204 - Gardner R., 1972, Attitudes and Motivation in Second-Language Learning - Gardner R., 1985, ATTITUDE MOTIVATION - Glanzel W, 1996, SCIENTOMETRICS, V35, P167, DOI 10.1007/BF02018475 - Gordin MichaelD., 2015, SCI BABEL SCI WAS DO, DOI [10.7208/chicago/9780226000329.001.0001, DOI 10.7208/CHICAGO/9780226000329.001.0001] - Hajar A, 2025, J MULTILING MULTICUL, V46, P1229, DOI 10.1080/01434632.2023.2230962 - KESSLER MM, 1963, AM DOC, V14, P10, DOI 10.1002/asi.5090140103 - Koo M, 2023, HELIYON, V9, DOI 10.1016/j.heliyon.2023.e16780 - Limeranto J. 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Teach. -PD OCT -PY 2024 -VL 27 -IS 2 -BP 818 -EP 843 -DI 10.24071/llt.v27i2.8058 -PG 26 -WC Education & Educational Research; Language & Linguistics -WE Emerging Sources Citation Index (ESCI) -SC Education & Educational Research; Linguistics -GA W3S1U -UT WOS:001417807800015 -OA gold -DA 2025-07-11 -ER - -PT J -AU Prakash, S - Agrawal, A - Singh, R - Singh, RK - Zindani, D -AF Prakash, Surya - Agrawal, Anubhav - Singh, Ranbir - Singh, Rajesh Kumar - Zindani, Divya -TI A decade of grey systems: theory and application - bibliometric overview - and future research directions -SO GREY SYSTEMS-THEORY AND APPLICATION -LA English -DT Review -DE Grey systems; Grey theory; Bibliometric analysis; Retrospective - analysis; Literature review -ID TRENDS; IMPACT -AB Purpose Grey Systems: Theory and Application (GSTA) journal started publication in 2011 and completed a decade in 2021. The purpose of this study is to provide a detailed bibliometric analysis of the articles published in GSTA and their content primary trends and themes. Design/methodology/approach This study uses the Web of Science (WoS) database to analyze the content of published articles. A range of bibliometric analyses and indicators are applied to analyze the GSTA article content using science mapping tools of the Bibliometrix package in the R environment. Findings The GSTA publishes around 28 articles each year with citations of this work steadily growing over time. The impact of these publications is measured as total mean citations which increased from 0 to 11. The journal has attracted contributors from around the globe, most often affiliated with China, India and Europe. Thematic evolution of the journal's themes reveals that it has expanded its scope to include topics such as relational analysis, decision making, incidence analysis, and forecasting, hybrid grey-fuzzy or grey-rough modeling, etc. Research limitations/implications The study is majorly based on GSTA data available on the WoS database. Originality/value This study provides the first overview of GSTA's publication and citation trends as well as the evolution of its thematic structure. It also suggests future directions that the journal might take to strengthen its position. -C1 [Prakash, Surya] IIHMR Univ, Sch Pharma Management, Jaipur, Rajasthan, India. - [Agrawal, Anubhav] BML Munjal Univ, ECE Dept, Gurgaon, India. - [Singh, Ranbir] BML Munjal Univ, Dept Mech Engn, Gurgaon, India. - [Singh, Rajesh Kumar] Management Dev Inst Gurgaon, Gurgaon, India. - [Zindani, Divya] SSN Coll Engn, Dept Mech Engn, Chennai, Tamil Nadu, India. -C3 BML Munjal University; BML Munjal University; Management Development - Institute (MDI); SSN College of Engineering -RP Prakash, S (corresponding author), IIHMR Univ, Sch Pharma Management, Jaipur, Rajasthan, India. -EM suryayadav8383@gmail.com -RI Zindani, Divya/AAI-3933-2020; Prakash, Surya/O-8135-2017; PRAKASH, - SURYA/O-8135-2017; Singh, Rajesh/K-2998-2019 -OI Singh, Dr Ranbir/0000-0001-9773-6695; Prakash, - Surya/0000-0003-4147-9399; -CR Andersen N, 2021, INT J HUM RESOUR MAN, V32, P4687, DOI 10.1080/09585192.2019.1661267 - Baker HK, 2021, J CORP FINANC, V66, DOI 10.1016/j.jcorpfin.2020.101572 - 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Prakash S, 2022, INT J LEAN SIX SIG, V13, P295, DOI 10.1108/IJLSS-12-2020-0219 - Quanda Zhang, 2014, Grey Systems: Theory and Application, V4, P311, DOI 10.1108/GS-11-2013-0025 - Rahimnia Fariborz, 2011, Grey Systems: Theory and Application, V1, P33, DOI 10.1108/20439371111106713 - Scarlat Emil, 2011, Grey Systems: Theory and Application, V1, P19, DOI 10.1108/20439371111106704 - Shuaib W, 2015, AM J CARDIOL, V115, P972, DOI 10.1016/j.amjcard.2015.01.029 - Si-feng Liu, 2011, Grey Systems: Theory and Application, V1, P8, DOI 10.1108/20439371111106696 - Sifeng Liu, 2013, Grey Systems: Theory and Application, V3, P7, DOI 10.1108/20439371311293651 - Sifeng Liu, 2012, Grey Systems: Theory and Application, V2, P341, DOI 10.1108/20439371211273230 - Sifeng Liu, 2012, Grey Systems: Theory and Application, V2, P89, DOI 10.1108/20439371211260081 - Wang C, 2019, INT J LOGIST-RES APP, V22, P304, DOI 10.1080/13675567.2018.1526262 - Xu XH, 2018, INT J PROD ECON, V204, P160, DOI 10.1016/j.ijpe.2018.08.003 - Xu Z., 2019, Journal of Data, Information and Management, V1, P3, DOI [10.1007/s42488-019-00001-2, DOI 10.1007/S42488-019-00001-2, 10.3390/su10010166] - Yin MS, 2013, EXPERT SYST APPL, V40, P2767, DOI 10.1016/j.eswa.2012.11.002 - ZADEH LA, 1965, INFORM CONTROL, V8, P338, DOI 10.1016/S0019-9958(65)90241-X -NR 43 -TC 18 -Z9 18 -U1 1 -U2 29 -PU EMERALD GROUP PUBLISHING LTD -PI BINGLEY -PA HOWARD HOUSE, WAGON LANE, BINGLEY BD16 1WA, W YORKSHIRE, ENGLAND -SN 2043-9377 -EI 2043-9385 -J9 GREY SYST -JI Grey Syst. -PD JAN 25 -PY 2023 -VL 13 -IS 1 -BP 14 -EP 33 -DI 10.1108/GS-03-2022-0030 -EA JUN 2022 -PG 20 -WC Mathematics, Interdisciplinary Applications -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Mathematics -GA 8F5XO -UT WOS:000814801700001 -DA 2025-07-11 -ER - -PT J -AU Musova, Z - Musa, H - Rech, F -AF Musova, Zdenka - Musa, Hussam - Rech, Frederik -TI Circular economy challenges: a bibliometric exploration of cognitive and - behavioral barriers -SO JOURNAL OF ORGANIZATIONAL CHANGE MANAGEMENT -LA English -DT Article; Early Access -DE Circular economy; Cognitive barriers; Behavioral barrier; Bibliometric - analysis; Scopus -ID METAANALYSIS; HOUSEHOLDS; SHIFT; TOOL -AB PurposeDespite its growing prominence, the adoption and implementation of circular economy practices remain hindered by a range of systemic, institutional, cognitive and behavioral barriers. While technical and economic challenges have received significant attention, the cognitive and psychological dimensions of these barriers are still underexplored. The paper aims to analyze the current trends and set the future research agenda for multidisciplinary research on the intersection of circular economy and cognitive and behavioral barriers.Design/methodology/approachBibliographic data on cognitive and behavioral barriers in circular economy practices were extracted from the SCOPUS database and analyzed using VOSviewer software for visualization and Bibliometrix R for performance analysis.FindingsThis paper analyzes 814 multidisciplinary publications on cognitive and behavioral barriers in circular economy practices from 1983 to 2023. For this, the paper identifies key research themes, influential authors, journals and trends in literature. Also, the paper visualizes the mapping of the co-occurrence of keywords and author collaboration networks. Despite examining the intersection of circular economy and behavioral barriers, the co-occurrence analysis highlights a persistent gap in fully integrating these two fields, emphasizing the need for more interdisciplinary research.Originality/valueThe paper provides a holistic view of trends and future research directions for multidisciplinary research on the intersection of circular economy and cognitive and behavioral barriers, based on performance analysis and science mapping, offering a unique contribution to the literature. -C1 [Musova, Zdenka] Matej Bel Univ Banska Bystrica, Dept Corp Econ & Management, Banska Bystrica, Slovakia. - [Musa, Hussam] Matej Bel Univ Banska Bystrica, Dept Finance & Accounting, Banska Bystrica, Slovakia. - [Rech, Frederik] Beijing Inst Technol, Sch Econ, Beijing, Peoples R China. -C3 Matej Bel University; Matej Bel University; Beijing Institute of - Technology -RP Rech, F (corresponding author), Beijing Inst Technol, Sch Econ, Beijing, Peoples R China. -EM zdenka.musova@umb.sk; hussam.musa@umb.sk; frederikrech@gmail.com -RI MUSA, Hussam/C-9944-2019; Rech, Frederik/JDD-0709-2023 -FU Scientific Grant Agency of Slovak Republic [APVV-23-0018]; Project VEGA - [1/0479/23, 1/0120/25]; Scientific Grant Agency of The Ministry of - Education, Research, Development and Youth of the Slovak Republic -FX This paper has been supported by the Scientific Grant Agency of Slovak - Republic under contract No. APVV-23-0018 and project VEGA No. 1/0479/23 - "Research of circular consumer behavior in the context of STP marketing - model", and VEGA No. 1/0120/25 "Research of paradigms and determinants - of management processes and ESG implementation in the context of the - required financial performance of companies and changes resulting from - the CSRD directive". 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Organ. Chang. Manage. -PD 2025 MAY 14 -PY 2025 -DI 10.1108/JOCM-01-2025-0011 -EA MAY 2025 -PG 21 -WC Management -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA 2MM4X -UT WOS:001486171000001 -DA 2025-07-11 -ER - -PT J -AU Oluwadele, D - Singh, Y - Adeliyi, TT -AF Oluwadele, Deborah - Singh, Yashik - Adeliyi, Timothy T. -TI E-Learning Performance Evaluation in Medical Education-A Bibliometric - and Visualization Analysis -SO HEALTHCARE -LA English -DT Article -DE bibliometric analysis; e-learning; medical education; performance - evaluation -ID TECHNOLOGY ACCEPTANCE MODEL; SYSTEM USABILITY SCALE; STUDENTS; OUTCOMES -AB Performance evaluation is one of the most critical components in assuring the comprehensive development of e-learning in medical education (e-LMED). Although several studies evaluate performance in e-LMED, no study presently maps the rising scientific knowledge and evolutionary patterns that establish a solid background to investigate and quantify the efficacy of the evaluation of performance in e-LMED. Therefore, this study aims to quantify scientific productivity, identify the key terms and analyze the extent of research collaboration in this domain. We searched the SCOPUS database using search terms informed by the PICOS model, and a total of 315 studies published between 1991 and 2022 were retrieved. Performance analysis, science mapping, network analysis, and visualization were performed using R Bibliometrix, Biblioshiny, and VOSviewer packages. Findings reveal that authors are actively publishing and collaborating in this domain, which experienced a sporadic publication increase in 2021. Most of the top publications, collaborations, countries, institutions, and journals are produced in first-world countries. 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The transport industry is a crucial driving force for economic growth and social development. It is still necessary to make transportation infrastructure and services safer, cleaner, and more affordable to cope with increasing urbanization and mobility. This paper systematically examines the science mapping of building information modeling and digital twins technologies in the digitalization of transportation. Through the bibliometric and content analysis approaches, 493 related documents were screened and analyzed from the Web of Science and Scopus databases. The software programs VOSviewer and Bibliometrix were used to determine research trends and current gaps, which will be beneficial to future research in this vital field. The results showed that over 80% of the relevant documents have been published since 2018. China is the most productive country, followed by the United States and Italy, and Germany is the most cited and influential country. 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Chang'an University -RP Wang, JW (corresponding author), Changan Univ, Coll Transportat Engn, Xian 710064, Peoples R China.; Wang, JW (corresponding author), Minist Educ, Engn Res Ctr Highway Infrastruct Digitalizat, Xian 710064, Peoples R China.; Wang, JW (corresponding author), Engn Res Ctr Digital Construct & Management Trans, Xian 710064, Peoples R China.; Wang, JW (corresponding author), Xian Key Lab Digitalizat Transportat Infrastruct, Xian 710064, Peoples R China. -EM wjianwei@chd.edu.cn -RI ; Dong, Shi/KBC-6824-2024; Wang, Jianwei/AAW-9499-2020; ZHAO, - YANLI/AAE-3100-2022; Liu, Zhizhen/AGQ-4570-2022 -OI Gao, Chao/0000-0002-3158-397X; Liu, Zhizhen/0000-0001-8934-2805; Dong, - Shi/0000-0002-3147-7341 -FU Transportation Science and Technology Research Project of Hebei Province - [JX-202006]; Scientific Innovation Practice Project of Postgraduates of - Chang'an University [300103722012] -FX This research was funded by the Transportation Science and Technology - Research Project of Hebei Province, grant number JX-202006 and the - Scientific Innovation Practice Project of Postgraduates of Chang'an - University, grant number 300103722012. -CR Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Barricelli BR, 2019, IEEE ACCESS, V7, P167653, DOI 10.1109/ACCESS.2019.2953499 - Biancardo SA, 2021, J ADV TRANSPORT, V2021, DOI 10.1155/2021/8839362 - Biancardo SA, 2022, TRANSPORT RES REC, V2676, P105, DOI 10.1177/03611981211035751 - Biancardo SA, 2020, INFRASTRUCTURES-BASE, V5, DOI 10.3390/infrastructures5050041 - Biancardo SA, 2020, INFRASTRUCTURES-BASE, V5, DOI 10.3390/infrastructures5040037 - Bolton RN, 2018, J SERV MANAGE, V29, P776, DOI 10.1108/JOSM-04-2018-0113 - Broniewicz E, 2020, TRANSPORT RES D-TR E, V83, DOI 10.1016/j.trd.2020.102351 - Chang B, 2011, TRANSPORT RES D-TR E, V16, P429, DOI 10.1016/j.trd.2011.04.004 - Chaudhary S, 2021, J BUS RES, V137, P143, DOI 10.1016/j.jbusres.2021.07.052 - Costin A, 2018, AUTOMAT CONSTR, V94, P257, DOI 10.1016/j.autcon.2018.07.001 - Cui ZW, 2024, INT J LOGIST-RES APP, V27, P1277, DOI 10.1080/13675567.2022.2128094 - Cui ZW, 2022, TRANSPORT POLICY, V120, P11, DOI 10.1016/j.tranpol.2022.03.002 - de Palma A, 2022, TRANSPORT RES A-POL, V159, P372, DOI 10.1016/j.tra.2022.03.024 - Fazeli A, 2021, ENG CONSTR ARCHIT MA, V28, P2828, DOI 10.1108/ECAM-01-2020-0027 - Gao S, 2022, APPL SCI-BASEL, V12, DOI 10.3390/app12178574 - Guo JJ, 2024, DIGIT COMMUN NETW, V10, P237, DOI 10.1016/j.dcan.2022.05.023 - Jalaei F, 2021, INT J CONSTR MANAG, V21, P784, DOI 10.1080/15623599.2019.1583850 - Jalaei F, 2015, SUSTAIN CITIES SOC, V18, P95, DOI 10.1016/j.scs.2015.06.007 - Jiang F, 2021, AUTOMAT CONSTR, V130, DOI 10.1016/j.autcon.2021.103838 - Jung H, 2020, EXPERT SYST APPL, V162, DOI 10.1016/j.eswa.2020.113851 - Krey N, 2022, J RETAIL CONSUM SERV, V64, DOI 10.1016/j.jretconser.2021.102702 - Li YL, 2021, INT J ENV RES PUB HE, V18, DOI 10.3390/ijerph18147515 - Linnenluecke MK, 2020, AUST J MANAGE, V45, P175, DOI 10.1177/0312896219877678 - Megahed NA, 2022, URBAN SCI, V6, DOI 10.3390/urbansci6040067 - Peng K, 2023, IEEE T IND INFORM, V19, P3133, DOI 10.1109/TII.2022.3184070 - Rad MAH, 2021, AUTOMAT CONSTR, V123, DOI 10.1016/j.autcon.2020.103480 - Ranjbari M, 2020, INT J CONTEMP HOSP M, V32, P2575, DOI 10.1108/IJCHM-02-2020-0097 - Sergeeva N, 2018, INT J PROJ MANAG, V36, P1068, DOI 10.1016/j.ijproman.2018.09.002 - Su HN, 2010, SCIENTOMETRICS, V85, P65, DOI 10.1007/s11192-010-0259-8 - van Eck NJ, 2017, SCIENTOMETRICS, V111, P1053, DOI 10.1007/s11192-017-2300-7 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Varghese Varun, 2020, Journal of Big Data Analytics in Transportation, V2, P199, DOI 10.1007/s42421-020-00030-z - Visser M, 2021, QUANT SCI STUD, V2, P20, DOI [10.1162/qss_a_00112, 10.1162/qes_a_00112] - [王建伟 Wang Jianwei], 2020, [中国公路学报, China Journal of Highway and Transport], V33, P101 - Weismayer C, 2017, SCIENTOMETRICS, V113, P1757, DOI 10.1007/s11192-017-2555-z - Xu XL, 2022, IEEE INTERNET THINGS, V9, P1930, DOI 10.1109/JIOT.2021.3089204 - Xu XL, 2022, IEEE T IND INFORM, V18, P1414, DOI 10.1109/TII.2020.3040180 - Xue F, 2018, COMPUT-AIDED CIV INF, V33, P926, DOI 10.1111/mice.12378 - Zhang F, 2021, SUSTAIN CITIES SOC, V72, DOI 10.1016/j.scs.2021.103039 - Zhang GC, 2015, COMPUT-AIDED CIV INF, V30, P85, DOI 10.1111/mice.12063 - Zhang JS, 2020, ADV CIV ENG, V2020, DOI 10.1155/2020/8842113 - Zhu DW, 2022, IEEE T IND INFORM, V18, P4893, DOI 10.1109/TII.2021.3113879 -NR 43 -TC 17 -Z9 17 -U1 12 -U2 95 -PU MDPI -PI BASEL -PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND -EI 2076-3417 -J9 APPL SCI-BASEL -JI Appl. Sci.-Basel -PD NOV -PY 2022 -VL 12 -IS 21 -AR 11203 -DI 10.3390/app122111203 -PG 15 -WC Chemistry, Multidisciplinary; Engineering, Multidisciplinary; Materials - Science, Multidisciplinary; Physics, Applied -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Chemistry; Engineering; Materials Science; Physics -GA 6E4ZE -UT WOS:000883389100001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Ngamake, ST - Raveepatarakul, J - Sawang, S -AF Ngamake, Sakkaphat T. - Raveepatarakul, Jirapattara - Sawang, Sukanlaya -TI An Evolving Landscape of the Psychology of Judgment and Decision-Making: - A Bibliometric Analysis -SO ADMINISTRATIVE SCIENCES -LA English -DT Article -DE judgment and decision-making; JDM; psychology; applied psychology; - bibliometrics -ID HEURISTICS; BEHAVIOR; EMOTION; MODEL -AB As a discipline with an expansive and intricate landscape, the field of judgment and decision-making (JDM) has evolved significantly since the beginning of the 2020s. The extensive and intricate nature of this field might pose challenges for scholars and researchers in designing course content and curricula as well as in defining research boundaries. Several techniques from a bibliometric study, such as co-word analysis and co-citation analysis, can provide insights into the scopes and directions of the field. Previous bibliometric studies on the psychology of JDM have primarily analyzed published documents restricted either by content areas or by journal outlets. The present study attempts to analyze a collection of published documents with broad search terms (i.e., "judgment*" or "decision mak*") within the purview of the psychology subject area, separately by years of publication (from 2020 to 2022) using the bibliometrix package in the R environment. The most relevant journals and the most frequent keywords have suggested established areas of study, uncovering common themes, patterns, and trends. Beyond that, two science mapping techniques (i.e., keyword co-occurrence network and reference co-citation network) revealed 12 prominent themes that cut across the three-year period. These themes, alongside other intellectually stimulating issues, were discussed based on a comparison with outstanding book chapters and reviews. Implications for pedagogical purposes were also provided with a handful of notable resources. -C1 [Ngamake, Sakkaphat T.; Raveepatarakul, Jirapattara] Chulalongkorn Univ, Fac Psychol, Bangkok 10330, Thailand. - [Sawang, Sukanlaya] Edinburgh Napier Univ, Business Sch, Edinburgh EH14 1DJ, Scotland. -C3 Chulalongkorn University; Edinburgh Napier University -RP Ngamake, ST (corresponding author), Chulalongkorn Univ, Fac Psychol, Bangkok 10330, Thailand. -EM sakkaphat.n@chula.ac.th; jirapattara.r@chula.ac.th; - s.sawang@napier.ac.uk -RI Ngamake, Sakkaphat/HWQ-5579-2023; Sawang, Sukanlaya/W-3270-2019 -FU Psychology Center for Life-Span Development and Intergeneration, - Chulalongkorn University, The Second Century Fund (C2F); Psychology - Center for Life-Span Development [1384208000]; Second Century Fund -FX This project has been granted funds from Psychology Center for Life-Span - Development and Intergeneration, Chulalongkorn University, The Second - Century Fund (C2F): grant number 1384208000. -CR AJZEN I, 1991, ORGAN BEHAV HUM DEC, V50, P179, DOI 10.1016/0749-5978(91)90020-T - Akosah-Twumasi P., 2018, Front. 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Sci. -PD AUG -PY 2024 -VL 14 -IS 8 -AR 162 -DI 10.3390/admsci14080162 -PG 21 -WC Management -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA E8G4S -UT WOS:001305329500001 -OA Green Published, gold -DA 2025-07-11 -ER - -PT J -AU Donthu, N - Kumar, S - Pandey, N -AF Donthu, Naveen - Kumar, Satish - Pandey, Nitesh -TI A retrospective evaluation of Marketing Intelligence and - Planning: 1983-2019 -SO MARKETING INTELLIGENCE & PLANNING -LA English -DT Article -DE Marketing intelligence and planning; Scopus; Bibliometrix; H-index; - VOSviewer; Citation analysis; Gephi; Keyword analysis -ID BRAND EQUITY; CUSTOMER LOYALTY; IMPACT; ORIENTATION; PERCEPTIONS; - PERSONALITY; INDUSTRY; CREATION; TOURISM; FOOD -AB Purpose The purpose of this study is to map the development of articles published, citations, and themes of Marketing Intelligence and Planning (MIP) over the 37-year period of 1983-2019. Design/methodology/approach This study uses the Scopus database to identify the most-cited MIP articles and most-included authors, institutions and countries in MIP. The study uses bibliometric indicators, as well as tools such as bibliographic coupling, performance analysis and science mapping, to analyze the publication and citation structure of MIP. The study provides a temporal analysis of MIP publishing across different time periods. Findings MIP has an average publication of 43 articles each year, and the number of citations has grown substantially since it started publication. Although contributors to the journal come from around the globe, they most often are affiliated with the United Kingdom, United States, and Australia. Bibliographic coupling of documents reveals that the journal's primary focus has been on issues such as marketing planning, marketing theory, consumer behavior, global marketing, customer relationship management, customer service and branding. Co-authorship analysis reveals that the journal's collaborative network has grown. Research limitations/implications This study uses data from the Scopus database, and any limitations of the database have implications for the findings. 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Intell. Plan. -PD FEB 1 -PY 2021 -VL 39 -IS 1 -BP 48 -EP 73 -DI 10.1108/MIP-02-2020-0066 -EA JUN 2020 -PG 26 -WC Business -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA QE0QU -UT WOS:000538081500001 -DA 2025-07-11 -ER - -PT J -AU Dragomir, VD - Dumitru, M -AF Dragomir, Voicu D. - Dumitru, Madalina -TI The state of the research on circular economy in the European Union: A - bibliometric review -SO CLEANER WASTE SYSTEMS -LA English -DT Review -DE Circular economy; Bibliometric analysis; European Union; Regulatory - framework; Scopus; Strategy; Literature review; Science mapping; Co-word - analysis -ID MUNICIPAL SOLID-WASTE; MANAGEMENT; BARRIERS; HIERARCHY; DRIVERS; TOOL; - TRANSITION; FRAMEWORK; NETWORKS; VEHICLES -AB Before 2020, the European Commission adopted several strategies pursuing sustainable development in the European Union (EU). At the core of these strategies, we can find the circular economy (CE) which relies on the 3 R concept: reduce-reuse-recycle. Starting from the unique European regulatory context, the aim of the present review is to determine the degree to which the works published by researchers affiliated with institutions within the EU address the challenges identified at the EU level and respond to EU strategies in the field of the CE. A bibliometric analysis based on Scopus was performed using VOSviewer and the bibliometrix package in R. The sample is made up of 13,553 articles published between 2006 and 2023. The results show that there has been an increase in the number of articles and citations during the last years, in line with the adoption of relevant regulations. The co-word analysis generated five domain clusters: sustainable development and life cycle assessment; biomass production and waste valorization; materials and recycling; wastewater treatment and environmental pollution; carbon emissions reduction and energy recovery. Several topics are common to all EU countries, and they are strongly related to EU-wide strategies regarding the circular economy. 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Waste Syst. -PD APR -PY 2024 -VL 7 -AR 100127 -DI 10.1016/j.clwas.2023.100127 -EA JAN 2024 -PG 26 -WC Engineering, Environmental; Environmental Sciences -WE Emerging Sources Citation Index (ESCI) -SC Engineering; Environmental Sciences & Ecology -GA L1B9D -UT WOS:001348156000001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Omer, AAA - Zhang, CH - Liu, J - Shan, ZG -AF Omer, Altyeb Ali Abaker - Zhang, Chun-Hua - Liu, Jie - Shan, Zhi-guo -TI Comprehensive review of mapping climate change impacts on tea - cultivation: bibliometric and content analysis of trends, influences, - adaptation strategies, and future directions -SO FRONTIERS IN PLANT SCIENCE -LA English -DT Review -DE tea cultivation; climate change; tea quality; antioxidants; secondary - metabolites; adaptation strategies; sustainability; socioeconomic - impacts -ID CAMELLIA-SINENSIS; ACCUMULATION; FLAVAN-3-OLS; CATECHINS; STRESS -AB Climate change has a profound impact on tea cultivation, posing significant challenges to yield, quality, and sustainability due to stressors such as drought, temperature fluctuations, and elevated CO2 levels. This study aims to address these challenges by identifying and synthesizing key themes, influential contributions, and effective adaptation strategies for mitigating the impacts of climate change on tea production. A systematic bibliometric and content analysis was conducted on 328 peer-reviewed documents (2004-2023), following the PRISMA methodology. Performance analysis using Bibliometrix examined trends in publication output, leading contributors, and geographical distribution, while science mapping with VOSviewer revealed collaboration networks and thematic clusters. A detailed review of highly cited studies highlighted the primary climate variables affecting tea cultivation and identified innovative adaptation strategies, as well as critical knowledge gaps. The results show significant progress in understanding the physiological, biochemical, and molecular responses of tea plants to climate-induced stressors, including antioxidant mechanisms, secondary metabolite regulation, and genomic adaptations. Despite these advancements, challenges remain, particularly regarding the combined effects of multiple stressors, long-term adaptation strategies, and the socioeconomic implications of climate change. The findings underscore the need for interdisciplinary approaches that integrate molecular, ecological, and socioeconomic research to address these issues. This study provides a solid foundation for guiding future research, fostering innovative adaptation strategies, and informing policy interventions to ensure sustainable tea production in a changing climate. -C1 [Omer, Altyeb Ali Abaker; Zhang, Chun-Hua; Liu, Jie; Shan, Zhi-guo] Puer Univ, Sch Tea & Coffee, Puer, Peoples R China. - [Omer, Altyeb Ali Abaker; Zhang, Chun-Hua; Liu, Jie; Shan, Zhi-guo] Puer Univ, Yunnan Int Union Lab Digital Protect & Germplasm I, Puer, Peoples R China. -C3 Pu'er University; Pu'er University -RP Omer, AAA; Shan, ZG (corresponding author), Puer Univ, Sch Tea & Coffee, Puer, Peoples R China.; Omer, AAA; Shan, ZG (corresponding author), Puer Univ, Yunnan Int Union Lab Digital Protect & Germplasm I, Puer, Peoples R China. -EM altyebali@peu.edu.cn; 353879230@qq.com -RI Zhang, Chunhua/ISB-1530-2023; Ali Abaker Omer, Altyeb/JAC-0852-2023; ALI - ABAKER OMER, ALTYEB/JAC-0852-2023 -OI Ali Abaker Omer, Altyeb/0000-0001-9420-9910; -FU National Natural Science Foundation of China10.13039/501100001809; Pu'er - University, China; Yunnan International Union Laboratory for Digital - Protection and Germplasm Innovation Application of Tea Resource in China - [32360771]; National Natural Science Foundation of China - [202101BA070001-239]; Science and Technology Program of Yunnan - Provincial Department of Science and Technology; Pu'er Tea Processing - Engineering Research Center [2020XJGH08]; Key Scientific Research - Special Planning Project of Pu'er University [2024J1099]; Yunnan - Ministry of Education -FX The authors thank Pu'er University, China, and the Yunnan International - Union Laboratory for Digital Protection and Germplasm Innovation - Application of Tea Resource in China and Laos for their invaluable - institutional support. Special thanks are extended to the National - Natural Science Foundation of China (Grant No. 32360771) and the Science - and Technology Program of Yunnan Provincial Department of Science and - Technology (Grant No. 202101BA070001-239) for their generous financial - support, which was instrumental in conducting this research. We also - sincerely thank the Pu'er Tea Processing Engineering Research Center and - the Key Scientific Research Special Planning Project of Pu'er University - (Grant No. 2020XJGH08) for providing essential resources and technical - support. The constructive feedback and encouragement from our colleagues - at the Pu'er College Top-notch Innovation Team and the Yunnan Ministry - of Education (Grant No. 2024J1099) have significantly enriched this - work. Finally, we acknowledge the invaluable contribution of the - reviewers and editors for their constructive comments, which have - greatly improved the quality of this manuscript. 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Design/methodology/approach - Data were retrieved from the Scopus database for the period 1985-2024, targeting articles referencing accreditation in civil engineering education. Performance analysis was conducted using Microsoft Excel, OpenRefine and biblioMagika, while science mapping was performed with the Bibliometrix R Package and VOSviewer. Findings - The analysis demonstrates a consistent growth in publications on civil engineering education accreditation since 2000, with the United States leading contributions and Malaysia emerging as a notable contributor among developing countries. Contributions from 226 authors across worldwide institutions were identified. Six key research clusters were uncovered: (1) curricula and accreditation, (2) analytical and problem-solving skills, (3) construction practices and safety engineering, (4) undergraduate civil engineering programs, (5) professional standards in civil engineering and (6) research activities and development. Practical implications - The findings provide valuable insights for institutions offering civil engineering programs, highlighting the need to align curricula with accreditation frameworks to ensure educational quality. Emphasis is placed on integrating elements such as outcome-based education, competency development and continuous quality improvement to prepare graduates for industry demands and global professional standards. Originality/value - By offering a foundational framework for understanding the evolving landscape of accreditation, this study provides valuable guidance for institutions aiming to enhance educational quality and achieve alignment with international standards. -C1 [Ibrahim, Che Khairil Izam Che; Kamal, Norashikin Ahmad] Univ Teknol MARA, Coll Engn, Sch Civil Engn, Selangor, Malaysia. -C3 Universiti Teknologi MARA -RP Ibrahim, CKIC (corresponding author), Univ Teknol MARA, Coll Engn, Sch Civil Engn, Selangor, Malaysia. -EM chekhairil449@uitm.edu.my; norashikin7349@uitm.edu.my -RI Ibrahim, Che/I-1380-2019; Kamal, Norashikin/AAQ-5649-2020 -CR Abudayyeh O, 2000, J CONSTR ENG M ASCE, V126, P169, DOI 10.1061/(ASCE)0733-9364(2000)126:3(169) - Ahmi A., 2024, biblioMagika - Alhorani RAM, 2021, COGENT ENG, V8, DOI 10.1080/23311916.2021.1995109 - Anwar AA, 2018, J PROF ISS ENG ED PR, V144, DOI 10.1061/(ASCE)EI.1943-5541.0000364 - Anwar AA, 2015, J PROF ISS ENG ED PR, V141, DOI 10.1061/(ASCE)EI.1943-5541.0000246 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bechtel A.J., 2018, ASEE ANN C EXP C P J - Bosela P.A., 2012, STRUCT C 2011 - Cobo MJ, 2011, J AM SOC INF SCI TEC, V62, P1382, DOI 10.1002/asi.21525 - Delatte N.J., 2009, Forensic Engineering: From Failure to Understanding, V36130, P59 - Estes AC, 2008, INT J ENG EDUC, V24, P864 - Feisel LD, 2009, IEEE POTENTIALS, V28, P25, DOI 10.1109/MPOT.2009.932501 - Frank T., 2023, ASEE ANN C EXP C P J - Gagnon W., 2021, P 5 INT C BUILD EN E - Grigg NS, 2004, J PROF ISS ENG ED PR, V130, P160, DOI 10.1061/(ASCE)1052-3928(2004)130:3(160) - Gunnink B., 2010, ASEE ANN C EXP C P - Gwinn A.F., 2021, Virtual Conference, DOI [10.18260/1-237880, DOI 10.18260/1-237880] - Hamilton S.R., 2019, P ASEE ANN C EXP C P - Ho J, 2024, ENG MANAG J, V36, P353, DOI 10.1080/10429247.2023.2285657 - Hudyma N, 2016, GEOTECH SP, P643 - Ibrahim CKIC, 2021, J CIV ENG EDUC, V147, DOI 10.1061/(ASCE)EI.2643-9115.0000030 - Iqbal Khan M., 2016, Journal of King Saud University - Engineering Sciences, V28, P1, DOI 10.1016/j.jksues.2014.09.001 - Kipfmiller T.E., 2024, AM SOC ENG ED ANN C - Koehn E, 1997, J PROF ISS ENG ED PR, V123, P66, DOI 10.1061/(ASCE)1052-3928(1997)123:2(66) - Koehn E, 2006, J PROF ISS ENG ED PR, V132, P138, DOI 10.1061/(ASCE)1052-3928(2006)132:2(138) - Koehn E, 1999, J PROF ISS ENG ED PR, V125, P35, DOI 10.1061/(ASCE)1052-3928(1999)125:2(35) - Kumar A, 2025, QUAL ASSUR EDUC, V33, P376, DOI 10.1108/QAE-08-2024-0170 - Li CQ, 2025, INNOV LANG LEARN TEA, V19, P188, DOI 10.1080/17501229.2024.2352789 - Lin X., 2024, Behaviour and Information Technology, V1, P1 - Mazumder F.Q., 2024, P AM SOC ENG ED ANN - MCCUEN RH, 1985, J PROF ISS ENG-ASCE, V111, P88, DOI 10.1061/(ASCE)1052-3928(1985)111:3(88) - Mohamad M., 2021, Asian Journal of University Education, V17, P191 - Pilotte M.K., 2023, ASEE ANN C EXP C P J - Pocock J., 2007, P ASEE ANN C EXP ANN - Qiu SP, 2024, J ENG EDUC, V113, P767, DOI 10.1002/jee.20547 - Rocha B., 2022, P AM SOC ENG ED ANN - Russell JS, 2005, J PROF ISS ENG ED PR, V131, P118, DOI 10.1061/(ASCE)1052-3928(2005)131:2(118) - Said SM, 2013, INT J TECHNOL DES ED, V23, P313, DOI 10.1007/s10798-011-9180-6 - Seagren EA, 2011, J PROF ISS ENG ED PR, V137, P183, DOI 10.1061/(ASCE)EI.1943-5541.0000065 - Shane JS, 2018, CONSTRUCTION RESEARCH CONGRESS 2018: SUSTAINABLE DESIGN AND CONSTRUCTION AND EDUCATION, P118 - Swenty M., 2022, P ASEE ANN C EXP MIN - Swenty M.K., 2023, P ASEE ANN C EXP BAL - Tymvios N., 2019, ASEE ANN C EXP C P - Uziak J, 2014, J PROF ISS ENG ED PR, V140, DOI 10.1061/(ASCE)EI.1943-5541.0000172 - Van Eck N.J., 2019, Universiteit Leiden and CWTS Meaningful Metrics, V1, P1 - Welch R., 2004, P ASEE ANN C EXP SAL - Woelfel C., 2024, ASEE ANN C EXP C P J - Yehia S., 2012, Global Journal of Engineering Education, V14, P69 - Zhang JX, 2018, J PROF ISS ENG ED PR, V144, DOI 10.1061/(ASCE)EI.1943-5541.0000356 - Zhang JX, 2016, SUSTAINABILITY-BASEL, V8, DOI 10.3390/su8060525 -NR 50 -TC 0 -Z9 0 -U1 4 -U2 4 -PU EMERALD GROUP PUBLISHING LTD -PI Leeds -PA Floor 5, Northspring 21-23 Wellington Street, Leeds, W YORKSHIRE, - ENGLAND -SN 0968-4883 -EI 1758-7662 -J9 QUAL ASSUR EDUC -JI QUALITY ASSURANCE EDUCATION -PD 2025 MAR 11 -PY 2025 -DI 10.1108/QAE-12-2024-0271 -EA MAR 2025 -PG 18 -WC Education & Educational Research -WE Emerging Sources Citation Index (ESCI) -SC Education & Educational Research -GA Z6D9H -UT WOS:001439798300001 -DA 2025-07-11 -ER - -PT J -AU Kilinç, S -AF Kilinc, Sehide -TI Integrated Educational Research: A Bibliometric Analysis -SO PEGEM EGITIM VE OGRETIM DERGISI -LA English -DT Article -DE Integrated education; curriculum; bibliometric analysis; science mapping -ID CURRICULUM INTEGRATION; SCIENCE; TEACHERS; TOOL -AB This study aims to address the gap in integrated education research by uncovering the conceptual, intellectual, and social structure of the field, including the publication volume and recent developments in integrated education studies. For this purpose, the data were obtained from the Web of Science (WoS) and Scopus databases covering the years 1944-2023. 1486 data were accessed from 689 sources. The data were analyzed and visualized with the R-based Bibliometrix analysis and Vosviewer. In this study, citation analysis was used to identify prolific authors, important documents, and resources in the field of integrated education. In addition, co-authorship and co-citation analyses were used. The results of the study revealed that although there was not a great expansion in the first years of the publication of research on integrated education, there has been an increasing trend in this field in the last two decades. This study identified the contributions of countries, journals, authors, and widely cited articles to the field. The study concluded that many countries have made significant contributions to integrated education research, but most of the publications in this field have been published in the USA. In the analysis of the most productive journals, this study showed that journals publishing on medical education are more effective in this field. As a result, it is thought that the results of the study will provide a useful resource for researchers who want to conduct research in this field as it discusses both current research foci and research trends and research gaps. -C1 [Kilinc, Sehide] Yagizlar Primary Sch, Adana, Turkiye. -RP Kilinç, S (corresponding author), Yagizlar Primary Sch, Adana, Turkiye. -EM sehidearslanhan83@gmail.com -RI KILINC, Sehide/R-3727-2016 -CR Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Baker W. 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Ogr. Derg. -PY 2024 -VL 14 -IS 4 -BP 195 -EP 214 -DI 10.47750/pegegog.14.04.17 -PG 20 -WC Education & Educational Research -WE Emerging Sources Citation Index (ESCI) -SC Education & Educational Research -GA XY9W4 -UT WOS:001265368400017 -DA 2025-07-11 -ER - -PT J -AU Vit, P - Ekundayo, TC - Wang, ZW -AF Vit, Patricia - Ekundayo, Temitope Cyrus - Wang, Zhengwei -TI MAPPING SIX DECADES OF STINGLESS BEE HONEY RESEARCH: CHEMICAL QUALITY - AND BIBLIOMETRICS -SO INTERCIENCIA -LA English -DT Article -DE Bibliometrics; Chemical Composition; Meliponini; Pot-Honey; Stingless - Bee Honey -ID SCIENCE -AB Stingless bees (Apidae: Apinae: Meliponini) process honey in cerumen pots, thus it is called pot-honey. Almost 600 species of stingless bees produce tropical pot-honey. Despite the Codex Alimentarius Commission neglecting the international regulation of this relevant meliponine product, local and national regulations are growing since 2014. Besides the higher water content and free acidity, a recent discovery of the sugar trehalulose in pot-honey is one more distinctive trait. The great entomological biodiversity has an impact on chemical composition and bioactivity of the honey, as well as the botanical origin which has been less studied due to the vast number of stingless bee species compared to the unique Apis mellifera. A bibliometric review (1962-2022) was conducted to analyze the evolution of stingless bee honey scientific literature, prolific authors, most active institutions, most productive countries, major journals used to disseminate pot-honey research, to identify theme maps and their connections to scientific disciplines using the Scopus database and the bibliometrix software. The taxonomic structure for this bibliometric review was described. In these six decades, a Venezuelan author stood out, Universidad de Los Andes was the third institution with the highest number of publications, and Venezuela ranked as the sixth most productive country after Brazil, Malaysia, Mexico, the United States, and Indonesia. A word cloud, tree map, dendrogram, and conceptual map were visualized. The network of sources and the evolution of authors' keywords were mapped with VOSviewer. This review was the first comprehensive science mapping analysis of stingless bee honey. -C1 [Vit, Patricia] Univ Los Andes ULA, Merida, Venezuela. - [Vit, Patricia] Univ Los Andes, Fac Pharm & Bioanal, Food Sci Dept, Apitherapy & Bioact, Merida, Venezuela. - [Ekundayo, Temitope Cyrus] Durban Univ Technol, Dept Biotechnol & Food Sci, Steve Biko Campus, Durban, South Africa. - [Ekundayo, Temitope Cyrus] Univ Med Sci Ondo, Dept Microbiol, Ondo, Nigeria. - [Wang, Zhengwei] Chinese Acad Sci, CAS Key Lab Trop Forest Ecol, Xishuangbanna Trop Bot Garden, Kunming, Peoples R China. -C3 University of Los Andes Venezuela; Durban University of Technology; - Chinese Academy of Sciences; Xishuangbanna Tropical Botanical Garden, - CAS -RP Vit, P (corresponding author), Univ Los Andes ULA, Merida, Venezuela.; Vit, P (corresponding author), Univ Los Andes, Fac Pharm & Bioanal, Food Sci Dept, Apitherapy & Bioact, Merida, Venezuela. -EM vitolivier@gmail.com -RI EKUNDAYO, TEMITOPE CYRUS/H-3302-2015 -OI EKUNDAYO, TEMITOPE CYRUS/0000-0002-7781-3507 -CR ADAB, 2014, Agencia de Defesa Agropecuaria da Bahia. 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Social entrepreneurs have repeatedly stressed the critical need for financial support from social banks. This study aims to provide a bibliometric analysis of the status of the field in social finance and banking, recognising main topics from existing research and establishing future re-search challenges. Our study used science mapping workflow and multiple research questions to investigate the broad literature about social banking and finance. With in-depth bibliometric analysis, authors examined qualitative and quantitative variables as primary research infor-mation, relevant sources, subject areas, authors data, social, thematic and intellectual structure. The data was retrieved from Web of Science (WOS) and then analysed using Bibliometrix R-package. The analysis was based on a sample of 270 articles and demonstrates a multidisciplinary vision of the research flow investigated. Our results show several insights regarding journals, authors and geographical interest of this research stream. Specifically, the literature, although dwelling on social finance and banking, includes five theoretical and practical clusters as (1) people's well-being, combined with technological innovation, (2) governance, (3) ethical investment and sustainable development, (4) corporate social responsibility (CSR), and (5) transparency. The authors also note a line of research that observes technological solutions for the response to social and environmental problems. 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Evolutionary theory; Multinational enterprises; R&D internationalization -ID CATCH-UP STRATEGIES; TECHNOLOGICAL CAPABILITIES; BIBLIOMETRIC ANALYSIS; - KNOWLEDGE TRANSFER; DIRECT-INVESTMENT; INNOVATION; NETWORK; FIRMS; MNES; - MULTINATIONALS -AB Purpose - This paper aims to provide a focused review of international business (IB) literature on research and development (R&D) internationalization, assessing the progress and proposing future research directions. Design/methodology/approach - Total 167 peer-reviewed articles from IB journals (following the ABS list 2021 from 4* to 2) published between 1996 and 2022 are critically reviewed using a science-mapping approach. This paper used Bibliometrix R-package to analyze the retrieved bibliometric data. Additionally, a strategic diagram was developed to comprehend the maturity stage of various R&D internationalization concepts. Findings - Most studies on R&D internationalization are influenced by perspectives from advanced-economy multinational enterprises (AMNEs), while perspectives from emerging-economy multinational enterprises (EMNEs) are underrepresented. Considering the characteristics of emerging economies, firms from these locations might embark on and develop their R&D internationalization strategies differently. Investigating the emerging economy perspectives will enrich the understanding of R&D internationalization strategies for both AMNEs and EMNEs. Additionally, bringing different underutilized theoretical perspectives will help to untangle the anomalies observed in extant literature. Originality/value - This paper is among the few to scrutinize the IB literature on R&D internationalization by applying a unique combination of bibliometric techniques and a content analysis approach. 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As it is challenging to map soil and hydrological information that are characterised with high spatial and temporal variability, applications of machine learning in soil science and hydrology (AMLSH) have become popularised. To better understand the current state of AMLSH research, a scientific and quantitative approach was performed to statistically analyse publication information from 1973 to 2021 archived in the Scopus database using scientometric analysis tools, including VOSviewer, CiteSpace, and the opensource R package "bibliometrix". The results show a significant increase in the number of publications on AMLSH since 2006. The major contributions were identified based on country origins (China, the USA, and India), institutions (Hohai University, Islamic Azad University, and Wuhan University), and journals (Journal of Hydrology, Remote Sensing, and Geoderma). The keywords analysis of the AMLSH research demonstrates four research hotspots: neural network, artificial intelligence, machine learning, and soil. The most frequently utilised machine learning (ML) methods are neural networks, decision trees, random forests and other methods for image processing and predictive analysis. McBratney et al. 2003 is the most highly cited article. 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Zhang, Z - Zhou, YM - Yang, CX -AF Mao, Yukang - Fu, Qiangqiang - Su, Feng - Zhang, Wenjia - Zhang, Zhong - Zhou, Yimeng - Yang, Chuanxi -TI Trends in worldwide research on cardiac fibrosis over the period - 1989-2022: a bibliometric study -SO FRONTIERS IN CARDIOVASCULAR MEDICINE -LA English -DT Article -DE cardiac fibrosis; bibliometric; research trend; systematic review; - citespace; VOSviewer -ID CARDIOVASCULAR MAGNETIC-RESONANCE; MYOCARDIAL FIBROSIS; HEART-FAILURE; - ATRIAL-FIBRILLATION; WORKING GROUP; NITRIC-OXIDE; ALDOSTERONE; - ASSOCIATION; MECHANISMS; INFARCTION -AB BackgroundCardiac fibrosis is a hallmark of various end-stage cardiovascular diseases (CVDs) and a potent contributor to adverse cardiovascular events. During the past decades, extensive publications on this topic have emerged worldwide, while a bibliometric analysis of the current status and research trends is still lacking. MethodsWe retrieved relevant 13,446 articles on cardiac fibrosis published between 1989 and 2022 from the Web of Science Core Collection (WoSCC). Bibliometrix was used for science mapping of the literature, while VOSviewer and CiteSpace were applied to visualize co-authorship, co-citation, co-occurrence, and bibliographic coupling networks. ResultsWe identified four major research trends: (1) pathophysiological mechanisms; (2) treatment strategies; (3) cardiac fibrosis and related CVDs; (4) early diagnostic methods. The most recent and important research themes such as left ventricular dysfunction, transgenic mice, and matrix metalloproteinase were generated by burst analysis of keywords. The reference with the most citations was a contemporary review summarizing the role of cardiac fibroblasts and fibrogenic molecules in promoting fibrogenesis following myocardial injury. The top 3 most influential countries were the United States, China, and Germany, while the most cited institution was Shanghai Jiao Tong University, followed by Nanjing Medical University and Capital Medical University. ConclusionsThe number and impact of global publications on cardiac fibrosis has expanded rapidly over the past 30 years. These results are in favor of paving the way for future research on the pathogenesis, diagnosis, and treatment of cardiac fibrosis. -C1 [Mao, Yukang] Nanjing Med Univ, Affiliated Suzhou Hosp, Suzhou Municipal Hosp, Gusu Sch,Dept Cardiol, Suzhou, Peoples R China. - [Mao, Yukang] Nanjing Med Univ, Affiliated Hosp 1, Dept Cardiol, Nanjing, Peoples R China. - [Fu, Qiangqiang] Tongji Univ, Yangpu Hosp, Clin Res Ctr Gen Practice, Sch Med,Dept Gen Practice, Shanghai, Peoples R China. - [Su, Feng; Zhang, Wenjia; Zhang, Zhong; Zhou, Yimeng; Yang, Chuanxi] Tongji Univ, Yangpu Hosp, Sch Med, Dept Cardiol, Shanghai, Peoples R China. -C3 Nanjing Medical University; Nanjing Medical University; Tongji - University; Tongji University -RP Zhou, YM; Yang, CX (corresponding author), Tongji Univ, Yangpu Hosp, Sch Med, Dept Cardiol, Shanghai, Peoples R China. -EM zhouyimeng@medmail.com.cn; 2205515@tongji.edu.cn -RI ; Mao, Yukang/MGU-8546-2025; Yang, Xulin/O-2253-2014 -OI Yang, Chuanxi/0000-0002-6970-1214; -FU Youth Program of National Natural Science Foundation of China [82200379] -FX Funding This work was funded by the Youth Program of National Natural - 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Cardiovasc. Med. -PD JUN 5 -PY 2023 -VL 10 -AR 1182606 -DI 10.3389/fcvm.2023.1182606 -PG 18 -WC Cardiac & Cardiovascular Systems -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Cardiovascular System & Cardiology -GA J2DB0 -UT WOS:001007756800001 -PM 37342441 -OA gold, Green Published -DA 2025-07-11 -ER - -PT J -AU Kaya, A - Tuzcu, A -AF Kaya, Ayla - Tuzcu, Ayla -TI A Bibliometric Analysis of the 36-Year History of Cancer Nursing - (1987-2023) -SO CANCER NURSING -LA English -DT Article -DE Bibliometric analysis; Cancer nursing; Nursing; Science mapping; Web of - Science -ID TRENDS; MANAGEMENT; BUSINESS -AB BackgroundBibliometric analysis is an effective method for evaluating the publication characteristics and development of a journal. To our knowledge, this study is the first such analysis of the publications in Cancer Nursing.ObjectiveThis study aimed to analyze the publication characteristics and evolution of Cancer Nursing over a period of 36 years since its inception.MethodsBibliometric analysis was carried out on 3095 publications. Data were collected from the Web of Science Core Collection database on September 15, 2023. Data analysis was conducted with Web of Science Core Collection, VOSviewer, and Bibliometrix package in R software.ResultsThe results showed a steady increase in the citation and publication structure of Cancer Nursing. "Quality of life" was at the center of the studies, and "quality of life," "women," and "breast cancer" were identified as trend topics. The United States was both at the center of the cooperation network and was the country that contributed the most publications to the journal.ConclusionCancer Nursing has had an increasing contribution to and impact on cancer nursing in terms of the quality and citations of published articles. It was noted that the journal's network of collaboration has expanded globally and that its thematic diversity is high. Although quality of life, women, and breast cancer have been reported extensively, more studies addressing the concepts of "children," "support," and "needs" are needed in the journal.Implications for PracticeThis study not only enriches global readers in the field of cancer nursing but may also be beneficial in providing input to guide future research. -C1 [Kaya, Ayla] Akdeniz Univ, Fac Nursing, Dept Pediat Nursing, Antalya, Turkiye. - [Tuzcu, Ayla] Akdeniz Univ, Fac Nursing, Dept Publ Hlth Nursing, Antalya, Turkiye. - [Tuzcu, Ayla] Akdeniz Univ, Fac Nursing, Dept Publ Hlth Nursing, Dumlupinar Blvd, TR-07058 Antalya, Turkiye. -C3 Akdeniz University; Akdeniz University; Akdeniz University -RP Tuzcu, A (corresponding author), Akdeniz Univ, Fac Nursing, Dept Publ Hlth Nursing, Dumlupinar Blvd, TR-07058 Antalya, Turkiye. -EM aylakaya@akdeniz.edu.tr; ylatuzcu@hotmail.com -RI Tuzcu, Ayla/C-1045-2016; Kaya, PhD, RN, Ayla/I-6831-2017 -OI Kaya, PhD, RN, Ayla/0000-0002-0281-0299 -FU Cancer Nursing Editorial Board -FX The authors would like to thank the Cancer Nursing Editorial Board, the - journal team, and the authors who contributed data to this bibliometric - analysis. -CR Acedo FJ, 2006, J MANAGE STUD, V43, P957, DOI 10.1111/j.1467-6486.2006.00625.x - [Anonymous], 2020, World Migration Report - Bottomley A, 2019, EUR J CANCER, V121, P55, DOI 10.1016/j.ejca.2019.08.016 - Calvo-Schimmel A, 2023, CANCER NURS, V46, P417, DOI 10.1097/NCC.0000000000001139 - Choudhri AF, 2015, RADIOGRAPHICS, V35, P736, DOI 10.1148/rg.2015140036 - Clarke N, 2021, PREV MED, V145, DOI 10.1016/j.ypmed.2021.106430 - Dhawan S, 2020, CANCER NURS, V43, P269, DOI 10.1097/NCC.0000000000000693 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Dubner R, 2009, PAIN, V142, P9, DOI 10.1016/j.pain.2009.01.003 - El-Hussein A, 2021, ANTI-CANCER AGENT ME, V21, P149, DOI 10.2174/1871520620666200403144945 - Fischer JP, 2018, J PEDIATR ORTHOPED, V38, pE168, DOI 10.1097/BPO.0000000000001124 - Goh YS, 2021, INT J MENT HEALTH NU, V30, P637, DOI 10.1111/inm.12826 - Han CJ, 2020, CANCER NURS, V43, pE132, DOI 10.1097/NCC.0000000000000785 - Jacox A., 1994, Management of cancer pain. 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SJR, 2022, SCIMAGO J COUNTRY RA - Stephanos K, 2021, EMERG MED CLIN N AM, V39, P555, DOI 10.1016/j.emc.2021.04.007 - Su YB, 2020, J NURS MANAGE, V28, P317, DOI 10.1111/jonm.12925 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Verma S, 2020, J BUS RES, V118, P253, DOI 10.1016/j.jbusres.2020.06.057 - Zeleznik D, 2017, J ADV NURS, V73, P2407, DOI 10.1111/jan.13296 - Zhu JW, 2020, SCIENTOMETRICS, V123, P321, DOI 10.1007/s11192-020-03387-8 -NR 33 -TC 1 -Z9 1 -U1 5 -U2 34 -PU LIPPINCOTT WILLIAMS & WILKINS -PI PHILADELPHIA -PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA -SN 0162-220X -EI 1538-9804 -J9 CANCER NURS -JI Cancer Nurs. -PD JUL-AUG -PY 2024 -VL 47 -IS 4 -BP 252 -EP 260 -DI 10.1097/NCC.0000000000001324 -EA FEB 2024 -PG 9 -WC Oncology; Nursing -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Oncology; Nursing -GA WA4Q5 -UT WOS:001159831000001 -PM 38335453 -DA 2025-07-11 -ER - -PT J -AU Huang, HH - Chen, ZY - Chen, LJ - Cao, SM - Bai, DQ - Xiao, Q - Xiao, MZ - Zhao, QH -AF Huang, Huanhuan - Chen, Zhiyu - Chen, Lijuan - Cao, Songmei - Bai, Dingqun - Xiao, Qian - Xiao, Mingzhao - Zhao, Qinghua -TI Nutrition and sarcopenia: Current knowledge domain and emerging trends -SO FRONTIERS IN MEDICINE -LA English -DT Article -DE nutrition; sarcopenia; VOSviewer; co-words; bibliometric analysis -ID OLDER-ADULTS; MUSCLE; OPPORTUNITIES; CONSENSUS; CACHEXIA -AB ObjectiveNon-pharmacological management like nutrient supplements has shown positive impacts on muscle mass and strength, which has burgeoned clinical and research interest internationally. The aim of this study was to analyze the current knowledge domain and emerging trends of nutrition-related research in sarcopenia and provide implications for future research and strategies to prevent or manage sarcopenia in the context of aging societies. Materials and methodsNutrition- and sarcopenia-related research were obtained from the Web of Science Core Collection (WoSCC) database from its inception to April 1, 2022. Performance analysis, science mapping, and thematic clustering were performed by using the software VOSviewer and R package "bibliometrix." Bibliometric analysis (BA) guideline was applied in this study. ResultsA total of 8,110 publications were extracted and only 7,510 (92.60%) were selected for final analysis. The production trend in nutrition and sarcopenia research was promising, and 1,357 journals, 107 countries, 6,668 institutions, and 31,289 authors were identified in this field till 2021. Stable cooperation networks have formed in the field, but they are mostly divided by region and research topics. Health and sarcopenia, metabolism and nutrition, nutrition and exercise, body compositions, and physical performance were the main search themes. ConclusionsThis study provides health providers and scholars mapped out a comprehensive basic knowledge structure in the research in the field of nutrition and sarcopenia over the past 30 years. This study could help them quickly grasp research hotspots and choose future research projects. -C1 [Huang, Huanhuan; Chen, Lijuan; Cao, Songmei; Zhao, Qinghua] Chongqing Med Univ, Affiliated Hosp 1, Dept Nursing, Chongqing, Peoples R China. - [Chen, Zhiyu] Chongqing Med Univ, Affiliated Hosp 1, Dept Orthoped, Chongqing, Peoples R China. - [Cao, Songmei] Jiangsu Univ, Affiliated Hosp, Dept Nursing, Zhenjiang, Jiangsu, Peoples R China. - [Bai, Dingqun] Chongqing Med Univ, Affiliated Hosp 1, Dept Rehabil Med, Chongqing, Peoples R China. - [Xiao, Qian] Chongqing Med Univ, Affiliated Hosp 1, Dept Geriatr, Chongqing, Peoples R China. - [Xiao, Mingzhao] Chongqing Med Univ, Affiliated Hosp 1, Dept Urol, Chongqing, Peoples R China. -C3 Chongqing Medical University; Chongqing Medical University; Jiangsu - University; Chongqing Medical University; Chongqing Medical University; - Chongqing Medical University -RP Huang, HH; Zhao, QH (corresponding author), Chongqing Med Univ, Affiliated Hosp 1, Dept Nursing, Chongqing, Peoples R China. -EM hxuehao@126.com; 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Med. -PD OCT 26 -PY 2022 -VL 9 -AR 968814 -DI 10.3389/fmed.2022.968814 -PG 12 -WC Medicine, General & Internal -WE Science Citation Index Expanded (SCI-EXPANDED) -SC General & Internal Medicine -GA 6C5TE -UT WOS:000882075600001 -PM 36388910 -OA Green Published, gold -DA 2025-07-11 -ER - -PT J -AU Boonroungrut, C - Muangkaew, K - Phoyen, K - Vechpong, T - Punyakitphokin, W - Khawda, G - Nantachai, G - Eiamnate, N - Worakul, P - M'manga, C - Saroinsong, WP -AF Boonroungrut, Chinun - Muangkaew, Kanyarat - Phoyen, Kamol - Vechpong, Thitima - Punyakitphokin, Wananya - Khawda, Gunchanon - Nantachai, Gallayaporn - Eiamnate, Nuttawut - Worakul, Puangsoy - M'manga, Chilungamo - Saroinsong, Wulan Patria -TI Visualising the scientific landscape of global research in - self-compassion: A bibliometric analysis -SO KNOWLEDGE MANAGEMENT & E-LEARNING-AN INTERNATIONAL JOURNAL -LA English -DT Article -DE Self-compassion; Bibliometric analysis; Science mapping -ID SCIENCE -AB Research in self-compassion has rapidly increased. Providing a comprehension of the scientific knowledge landscape will be helpful for researchers to identify the gaps and develop future research ideas in this field without subjectivity. Thus, overarching structures in self-compassion Scopusindexed research were sought to be analysed here. Bibliometric techniques were used to extract documents indexed in Scopus under the domain of selfcompassion (N = 1,764 articles) using bibliophily, a web interface of the Bibliometrix 3.0 and VOSviewer to conduct analysis and visualisation. The number of published articles shows an upward trend; the United States occupies the leading position in publication volumes and citations. Undoubtedly, K. D. Neff and her sustained cited model were reported as a prolific author and influential article in self-compassion literature. The top affiliation was the University of Texas at Austin, which was the leading university in both production and citation. Mindfulness was a key journal that was considered in publication volume and received citations; however, authors trended to publish from diverse selected sources. The top 50 most frequently used terms were related to individual differences and psychological status. Finally, the thematic mapping provided a comprehensive illustration showing significant themes and knowledge gaps in self-compassion research, which categorised individual differences as basic, measurement validation as niche and PTSD as emerging themes. The current findings presented scientific mappings and extensive tables containing information that usefully proposes future directions and the critical broader scope of research in self-compassion. -C1 [Boonroungrut, Chinun; Muangkaew, Kanyarat; Phoyen, Kamol; Vechpong, Thitima; Punyakitphokin, Wananya; Khawda, Gunchanon; Worakul, Puangsoy] Silpakorn Univ, Fac Educ, Bangkok, Thailand. - [Nantachai, Gallayaporn] Chulalongkorn Univ, Fac Med, Bangkok, Thailand. - [Nantachai, Gallayaporn] Somdet Pra sungharaj Nyanasumvara Geriatr Hosp, Chon Buri, Thailand. - [Eiamnate, Nuttawut] Rajamangala Univ Technol Suvarnabhumi, Fac Liberal Arts, Nonthaburi, Thailand. - [M'manga, Chilungamo] Kamuzu Univ Hlth Sci, Sch Global & Publ Hlth, Blantyre, Malawi. - [Saroinsong, Wulan Patria] Univ Negri Surabay, Fac Educ, Surabaya, Indonesia. -C3 Silpakorn University; Chulalongkorn University; Rajamangala University - of Technology Suvarnabhumi -RP Boonroungrut, C (corresponding author), Silpakorn Univ, Fac Educ, Bangkok, Thailand. -EM boonroungrut_c@su.ac.th; saartyen_k@su.ac.th; kamol.pho2@gmail.com; - vtitima@yahoo.com; Punyakitphokin_w@silpakorn.edu; - gunchanon.kh@gmail.com; gallayaporn@gmail.com; injustic9@hotmail.com; - puangsor.w@psu.ac.th; cmmanga@kuhes.ac.mw; wulansaroinsong@unesa.ac.id -RI Saroinsong, Wulan/AAT-2411-2021 -CR Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Ball R., 2017, An Introduction to Bibliometrics: New Development and Trends - Barnard LK, 2011, REV GEN PSYCHOL, V15, P289, DOI 10.1037/a0025754 - Bluth K, 2018, SELF IDENTITY, V17, P605, DOI 10.1080/15298868.2018.1508494 - Boonroungrut C, 2022, INT J INSTR, V15, P457, DOI 10.29333/iji.2022.15126a - Börner K, 2003, ANNU REV INFORM SCI, V37, P179, DOI 10.1002/aris.1440370106 - Cañas AJ, 2023, KNOWL MANAG E-LEARN, V15, P369, DOI 10.34105/j.kmel.2023.15.021 - Cobo MJ, 2011, J AM SOC INF SCI TEC, V62, P1382, DOI 10.1002/asi.21525 - Crego A, 2022, PSYCHOL RES BEHAV MA, V15, P2599, DOI 10.2147/PRBM.S359382 - Della Corte V, 2021, SUSTAINABILITY-BASEL, V13, DOI 10.3390/su132212632 - Dervis H, 2019, J SCIENTOMETR RES, V8, P156, DOI 10.5530/jscires.8.3.32 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Gilbert P, 2009, Advances in Psychiatric Treatment, V15, P199, DOI [10.1192/apt.bp.107.005264, DOI 10.1192/APT.BP.107.005264] - Goldberg SB, 2017, PLOS ONE, V12, DOI 10.1371/journal.pone.0187298 - Gu J, 2020, ASSESSMENT, V27, P3, DOI 10.1177/1073191119860911 - Khawda G., 2023, Asian Education and Learning Review, V1, P11, DOI [10.14456/aelr.2023.2, DOI 10.14456/AELR.2023.2] - Kuhn TS., 1962, The structure of scientific revolutions - Thu HLT, 2021, EDUC SCI, V11, DOI 10.3390/educsci11070353 - Leary MR, 2007, J PERS SOC PSYCHOL, V92, P887, DOI 10.1037/0022-3514.92.5.887 - Luther L, 2020, MULTIMODAL TECHNOLOG, V4, DOI 10.3390/mti4020018 - MacBeth A, 2012, CLIN PSYCHOL REV, V32, P545, DOI 10.1016/j.cpr.2012.06.003 - Mongeon P, 2016, SCIENTOMETRICS, V106, P213, DOI 10.1007/s11192-015-1765-5 - Moral-Muñoz JA, 2020, PROF INFORM, V29, DOI 10.3145/epi.2020.ene.03 - Muris P, 2020, MINDFULNESS, V11, P1469, DOI 10.1007/s12671-020-01363-0 - Muris P, 2017, CLIN PSYCHOL PSYCHOT, V24, P373, DOI 10.1002/cpp.2005 - Neff K.D., 2011, SELF COMPASSION PROV - Neff KD, 2007, J RES PERS, V41, P139, DOI 10.1016/j.jrp.2006.03.004 - Neff KD, 2023, ANNU REV PSYCHOL, V74, P193, DOI 10.1146/annurev-psych-032420-031047 - Neff KD, 2021, MINDFULNESS, V12, P121, DOI 10.1007/s12671-020-01505-4 - Neff KD, 2003, SELF IDENTITY, V2, P223, DOI 10.1080/15298860390209035 - Neff KD, 2013, J CLIN PSYCHOL, V69, P28, DOI 10.1002/jclp.21923 - Perianes-Rodriguez A, 2016, J INFORMETR, V10, P1178, DOI 10.1016/j.joi.2016.10.006 - Pessin VZ, 2022, SCIENTOMETRICS, V127, P3695, DOI 10.1007/s11192-022-04406-6 - Raes F, 2011, CLIN PSYCHOL PSYCHOT, V18, P250, DOI 10.1002/cpp.702 - Saroinsong W. 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E-Learn. -PD MAR -PY 2024 -VL 16 -IS 1 -DI 10.34105/j.kmel.2024.16.009 -PG 23 -WC Education & Educational Research -WE Emerging Sources Citation Index (ESCI) -SC Education & Educational Research -GA LO5W3 -UT WOS:001187767600009 -OA gold -DA 2025-07-11 -ER - -PT J -AU Xu, HQ - Cheng, XY - Wang, T - Wu, SF - Xiong, YQ -AF Xu, Hanqing - Cheng, Xinyan - Wang, Ting - Wu, Shufen - Xiong, Yongqi -TI Mapping Neuroscience in the Field of Education through a Bibliometric - Analysis -SO BRAIN SCIENCES -LA English -DT Review -DE neuroscience; education; bibliometric analysis; research topics; - research trends -ID ANATOMICAL SCIENCES; MEDICAL-EDUCATION; EYE-MOVEMENTS; EMPATHY; BRAIN; - CHILDREN; STUDENTS; INTEGRATION; NEUROMYTHS; KNOWLEDGE -AB This study aimed to explore the core knowledge topics and future research trends in neuroscience in the field of education (NIE). In this study, we have explored the diffusion of neuroscience and different neuroscience methods (e.g., electroencephalography, functional magnetic resonance imaging, eye tracking) through and within education fields. A total of 549 existing scholarly articles and 25,886 references on neuroscience in the field of education (NIE) from the Web of Science Core Collection databases were examined during the following two periods: 1995-2013 and 2014-2022. The science mapping software Vosviewer and Bibliometrix were employed for data analysis and visualization of relevant literature. Furthermore, performance analysis, collaboration network analysis, co-citation network analysis, and strategic diagram analysis were conducted to systematically sort out the core knowledge in NIE. The results showed that children and cognitive neuroscience, students and medical education, emotion and empathy, and education and brain are the core intellectual themes of current research in NIE. Curriculum reform and children's skill development have remained central research issues in NIE, and several topics on pediatric research are emerging. The core intellectual themes of NIE revealed in this study can help scholars to better understand NIE, save research time, and explore a new research question. To the best of our knowledge, this study is one of the earliest documents to outline the NIE core intellectual themes and identify the research opportunities emerging in the field. -C1 [Xu, Hanqing; Wang, Ting; Xiong, Yongqi] Ningbo Univ, Coll Sci & Technol, Cixi 315211, Peoples R China. - [Cheng, Xinyan] McMaster Univ, Dept Sociol, Hamilton, ON L8S 4L8, Canada. - [Wu, Shufen] Ningbo Childhood Educ Coll, Ningbo 315336, Peoples R China. -C3 Ningbo University; McMaster University -RP Wang, T (corresponding author), Ningbo Univ, Coll Sci & Technol, Cixi 315211, Peoples R China.; Wu, SF (corresponding author), Ningbo Childhood Educ Coll, Ningbo 315336, Peoples R China. -EM wangting@nbu.edu.cn; 2013017@ncec.edu.cn -FU College of Science and Technology Ningbo University [YK202216]; Cixi - Social Science Association [2022SKY006]; K.C. Wong Magna Fund at Ningbo - University -FX This research was funded by the College of Science and Technology Ningbo - University (YK202216), Cixi Social Science Association (2022SKY006), and - the K.C. 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-PT J -AU Yalcinkaya, T - Yucel, SC -AF Yalcinkaya, Turgay - Yucel, Sebnem Cinar -TI Bibliometric and content analysis of ChatGPT research in nursing - education: The rabbit hole in nursing education -SO NURSE EDUCATION IN PRACTICE -LA English -DT Article -DE ChatGPT; OpenAI; Artificial intelligence; Bibliometrics analysis; - Nursing education; Nursing students -AB Aim: This study was conducted to perform the bibliometric and content analysis of ChatGPT studies in nursing education. Background: ChatGPT is an artificial intelligence -based chatbot developed by OpenAI. The benefits and limitations of the use of ChatGPT in nursing education are still discussed; however, it is a tool having potential to be used in nursing education. Design: Bibliometric and content analysis. Methods: The study data were scanned through Scopus and Web of Science. Bibliometric analysis was carried out with VOSViewer and Bibliometrix software. In the bibliometric analysis, science mapping and performance analysis techniques were used. Various bibliometric data, including most cited publications, journals and countries, were analyzed and visualized. The synthetic knowledge synthesis method was used in content analysis. Results: We analyzed 53 publications to which 151 authors contributed. The publications had been published in 29 different journals. The average number of citations of publications is 8.2. It was determined that most of the articles were published in Nurse Education Today and Nurse Educator journals and that the leading countries were the USA and Canada. It was observed that international cooperation on the issue was weak. The most frequently mentioned keywords in the publications were "ChatGPT", "artificial intelligence" and "nursing". The following three themes emerged after the content analysis: (1) Integration of ChatGPT into nursing education; (2) Potential benefits and limitations of ChatGPT; and (3) Stepping down the rabbit hole. Conclusions: We expect that the results of the study can give nursing faculties and academics ideas about the current status of ChatGPT in nursing education and enable them to make inferences for the future. -C1 [Yalcinkaya, Turgay] Sinop Univ, Fac Hlth Sci, Dept Nursing, Sinop, Turkiye. - [Yucel, Sebnem Cinar] Ege Univ, Dept Fundamentals Nursing, Nursing Fac, Izmir, Turkiye. -C3 Sinop University; Ege University -RP Yalcinkaya, T (corresponding author), Sinop Univ, Fac Hlth Sci, Dept Nursing, Sinop, Turkiye. -EM tyalcinkaya@sinop.edu.tr -RI YUCEL, SEBNEM/A-3675-2019; Yalcinkaya, Turgay/HFZ-8650-2022 -OI Yalcinkaya, Turgay/0000-0002-0115-295X -CR Abdulai AF, 2023, NURS INQ, V30, DOI 10.1111/nin.12556 - Ahmed SK, 2023, ANN BIOMED ENG, V51, P2351, DOI 10.1007/s10439-023-03262-6 - Allen C, 2023, INT J NURS STUD, V145, DOI 10.1016/j.ijnurstu.2023.104522 - Archibald MM, 2023, J ADV NURS, V79, P3648, DOI 10.1111/jan.15643 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Athilingam P, 2024, TEACH LEARN NURS, V19, P97, DOI 10.1016/j.teln.2023.11.004 - Barrington NM, 2023, MED SCI-BASEL, V11, DOI 10.3390/medsci11030061 - Berse S, 2024, ANN BIOMED ENG, V52, P130, DOI 10.1007/s10439-023-03296-w - Buchanan Christine, 2021, JMIR Nurs, V4, pe23933, DOI 10.2196/23933 - Byrne MD, 2024, NURS EDUC PERSPECT, V45, P63, DOI 10.1097/01.NEP.0000000000001225 - Castonguay A, 2023, NURS EDUC TODAY, V129, DOI 10.1016/j.nedt.2023.105916 - Chan MMK, 2023, NURS EDUC, V48, pE200, DOI 10.1097/NNE.0000000000001476 - Chang CY, 2024, EDUC TECHNOL SOC, V27, P215, DOI 10.30191/ETS.202401_27(1).TP02 - Choi EPH, 2023, NURS EDUC TODAY, V125, DOI 10.1016/j.nedt.2023.105796 - Christiansen M., 2023, H. ogre Utbild., V13, P56, DOI [10.23865/hu.v13.5331, DOI 10.23865/HU.V13.5331] - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Echchakoui S, 2020, J MARK ANAL, V8, P165, DOI 10.1057/s41270-020-00081-9 - Evans J, 2024, NURS EDUC, V49, pE41, DOI 10.1097/NNE.0000000000001424 - Goktas P, 2024, TEACH LEARN NURS, V19, pe358, DOI 10.1016/j.teln.2023.12.014 - Goktas P, 2023, SKIN RES TECHNOL, V29, DOI 10.1111/srt.13417 - Gosak L, 2024, NURSE EDUC PRACT, V75, DOI 10.1016/j.nepr.2024.103888 - Harder N, 2023, CLIN SIMUL NURS, V78, P1, DOI 10.1016/j.ecns.2023.02.011 - Harmon J, 2021, NURS EDUC TODAY, V97, DOI 10.1016/j.nedt.2020.104700 - He SK, 2024, ASIAN J SURG, V47, P784, DOI 10.1016/j.asjsur.2023.10.034 - Huang HM, 2023, HEALTHCARE-BASEL, V11, DOI 10.3390/healthcare11212855 - Irwin P, 2023, NURS EDUC TODAY, V127, DOI 10.1016/j.nedt.2023.105835 - Kokol P, 2022, ELECTRONICS-SWITZ, V11, DOI 10.3390/electronics11162485 - Kokol P, 2019, NURS OUTLOOK, V67, P680, DOI 10.1016/j.outlook.2019.04.009 - Krüger L, 2023, MED KLIN-INTENSIVMED, V118, P534, DOI 10.1007/s00063-023-01038-3 - Levin G, 2023, ARCH GYNECOL OBSTET, V308, P1785, DOI 10.1007/s00404-023-07081-x - Liu HY, 2024, AESTHET PLAST SURG, V48, P1644, DOI 10.1007/s00266-023-03709-0 - Liu JL, 2023, NURS OUTLOOK, V71, DOI 10.1016/j.outlook.2023.102064 - Lo CK, 2023, EDUC SCI, V13, DOI 10.3390/educsci13040410 - Miao Hongyu, 2023, Asian Pac Isl Nurs J, V7, pe48136, DOI 10.2196/48136 - Mukherjee D, 2022, J BUS RES, V148, P101, DOI 10.1016/j.jbusres.2022.04.042 - O'Connor S, 2023, NURSE EDUC PRACT, V66, DOI 10.1016/j.nepr.2022.103537 - O'Connor S, 2020, NURSE EDUC PRACT, V56, DOI 10.1016/j.nepr.2021.103224 - OpenAI, 2023, Introd. 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Pract. -PD MAY -PY 2024 -VL 77 -AR 103956 -DI 10.1016/j.nepr.2024.103956 -EA APR 2024 -PG 10 -WC Nursing -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Nursing -GA SB9R6 -UT WOS:001232121800001 -PM 38653086 -DA 2025-07-11 -ER - -PT J -AU Hu, LY - Yang, JK - Liu, T - Zhang, JH - Huang, XX - Yu, HB -AF Hu, Liyu - Yang, Jikang - Liu, Ting - Zhang, Jinhuan - Huang, Xingxian - Yu, Haibo -TI Hotspots and Trends in Research on Treating Pain with - Electroacupuncture: A Bibliometric and Visualization Analysis from 1994 - to 2022 -SO JOURNAL OF PAIN RESEARCH -LA English -DT Article -DE bibliometrics; electroacupuncture; pain; VOSviewer; CiteSpace; - blibliometrix -ID LOW-BACK-PAIN; MULTIMODAL ANALGESIA; SHAM ACUPUNCTURE; BRAIN NETWORK; - RAT MODEL; ACTIVATION; MECHANISM; THERAPY; STIMULATION; MANAGEMENT -AB Purpose: Electroacupuncture is widely used to pain management. A bibliometric analysis was conducted to identify the hotspots and trends in research on electroacupuncture for pain. Methods: We retrieved studies published from 1994-2022 on the topic of pain relief by electroacupuncture from the Web of Science Core Collection database. We comprehensively analysed the data with VOSviewer, CiteSpace, and bibliometrix. Seven aspects of the data were analysed separately: annual publication outputs, countries, institutions, authors, journals, keywords and references. Results: A total of 2030 papers were analysed, and the number of worldwide publications continuously increased over the period of interest. The most productive country and institution in this field were China and KyungHee University. Evidence-Based Complementary and Alternative Medicine was the most productive journal, and Pain was the most co-cited journal. Han Jisheng, Fang Jianqiao, and Lao Lixing were the most representative authors. Based on keywords and references, three active areas of research on EA for pain were mechanisms, randomized controlled trials, and perioperative applications. Three emerging trends were functional magnetic resonance imaging (fMRI), systematic reviews, and knee osteoarthritis. Conclusion: This study comprehensively analysed the research published over the past 28 years on electroacupuncture for pain treatment, using bibliometrics and science mapping analysis. This work presents the current status and landscape of the field and may serve as a valuable resource for researchers. Chronic pain, fMRI-based mechanistic research, and the perioperative application of electroacupuncture are among the likely foci of future research in this area. -C1 [Hu, Liyu; Yang, Jikang; Liu, Ting; Zhang, Jinhuan; Huang, Xingxian; Yu, Haibo] Guangzhou Univ Chinese Med, Clin Med Coll 4, Guangzhou Univ Chinese Med, Shenzhen, Peoples R China. - [Yu, Haibo] Guangzhou Univ Chinese Med, Clin Med Coll 4, 1 Fuhua Rd, Shenzhen 518000, Peoples R China. -C3 Guangzhou University of Chinese Medicine; Guangzhou University of - Chinese Medicine -RP Yu, HB (corresponding author), Guangzhou Univ Chinese Med, Clin Med Coll 4, 1 Fuhua Rd, Shenzhen 518000, Peoples R China. -EM 13603066098@163.com -OI Hu, Li-yu/0000-0002-3029-8560 -FU Shenzhen's Sanming Project [SZSM201612001] -FX This work was supported by Shenzhen's Sanming Project (SZSM201612001) . -CR Alfhaily F, 2007, CLIMACTERIC, V10, P371, DOI 10.1080/13697130701612315 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bigeleisen PE, 2015, CURR OPIN ANESTHESIO, V28, P89, DOI 10.1097/ACO.0000000000000147 - Cassu RN, 2008, VET ANAESTH ANALG, V35, P52, DOI 10.1111/j.1467-2995.2007.00347.x - Chen Chaomei, 2020, Front Res Metr Anal, V5, P607286, DOI 10.3389/frma.2020.607286 - Chen CM, 2014, J ASSOC INF SCI TECH, V65, P334, DOI 10.1002/asi.22968 - Chen CM, 2006, J AM SOC INF SCI TEC, V57, P359, DOI 10.1002/asi.20317 - Chen CM, 2004, P NATL ACAD SCI USA, V101, P5303, DOI 10.1073/pnas.0307513100 - Cheng SPNI, 2022, MED ACUPUNCT, V34, P49, DOI 10.1089/acu.2021.0072 - Chu WCW, 2012, J NEUROGASTROENTEROL, V18, P305, DOI 10.5056/jnm.2012.18.3.305 - Cobo MJ, 2011, J INFORMETR, V5, P146, DOI 10.1016/j.joi.2010.10.002 - Cohen SP, 2021, LANCET, V397, P2082, DOI 10.1016/S0140-6736(21)00393-7 - Dai WJ, 2019, EVID-BASED COMPL ALT, V2019, DOI 10.1155/2019/8413576 - Du JY, 2020, BRAIN RES, V1733, DOI 10.1016/j.brainres.2020.146719 - Fangtham M, 2019, LUPUS, V28, P703, DOI 10.1177/0961203319841435 - Fei YT, 2022, BMJ-BRIT MED J, V376, DOI 10.1136/bmj-2021-064345 - Fillingim RB, 2009, J PAIN, V10, P447, DOI 10.1016/j.jpain.2008.12.001 - Fisher H, 2021, FRONT NEUROL, V12, DOI 10.3389/fneur.2021.754670 - Fu X, 2006, BRAIN RES, V1078, P212, DOI 10.1016/j.brainres.2006.01.026 - Han JS, 2004, NEUROSCI LETT, V361, P258, DOI 10.1016/j.neulet.2003.12.019 - Han JS, 2003, TRENDS NEUROSCI, V26, P17, DOI 10.1016/S0166-2236(02)00006-1 - Harris RE, 2009, NEUROIMAGE, V47, P1077, DOI 10.1016/j.neuroimage.2009.05.083 - Hashmi JA, 2014, PAIN, V155, P10, DOI 10.1016/j.pain.2013.07.039 - He KL, 2022, EVID-BASED COMPL ALT, V2022, DOI 10.1155/2022/4478444 - He KL, 2022, J PAIN RES, V15, P1257, DOI 10.2147/JPR.S361652 - Hinman RS, 2014, JAMA-J AM MED ASSOC, V312, P1313, DOI 10.1001/jama.2014.12660 - Huang LY, 2023, COMPLEMENT THER MED, V72, DOI 10.1016/j.ctim.2023.102915 - Ioannidis JPA, 2019, PLOS BIOL, V17, DOI 10.1371/journal.pbio.3000384 - Ishiyama S, 2022, PAIN MED, V23, P1560, DOI 10.1093/pm/pnac048 - Jiang Y, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0066815 - Kim HY, 2009, PAIN, V145, P332, DOI 10.1016/j.pain.2009.06.035 - Kong J, 2007, NEUROIMAGE, V34, P1171, DOI 10.1016/j.neuroimage.2006.10.019 - Koo ST, 2002, PAIN, V99, P423, DOI 10.1016/S0304-3959(02)00164-1 - Langevin HM, 2015, J ALTERN COMPLEM MED, V21, P113, DOI 10.1089/acm.2014.0186 - Leung A, 2014, MOL PAIN, V10, DOI 10.1186/1744-8069-10-23 - Lewis K, 2010, CLIN J PAIN, V26, P60, DOI 10.1097/AJP.0b013e3181bad71e - Leydesdorff L, 2016, SCIENTOMETRICS, V109, P2077, DOI 10.1007/s11192-016-2119-7 - Li Aihui, 2007, BMC Complement Altern Med, V7, P27 - Li Y, 2019, J TRADIT CHIN MED, V39, P740 - Liang YD, 2017, J PAIN RES, V10, P951, DOI 10.2147/JPR.S132808 - Lin JG, 2012, AM J CHINESE MED, V40, P219, DOI 10.1142/S0192415X12500176 - Lin JG, 2002, PAIN, V99, P509, DOI 10.1016/S0304-3959(02)00261-0 - Linde K, 2010, FORSCH KOMPLEMENTMED, V17, P259, DOI 10.1159/000320374 - Liu P, 2009, J MAGN RESON IMAGING, V30, P41, DOI 10.1002/jmri.21805 - Ma F, 2004, BRAIN RES BULL, V63, P509, DOI 10.1016/j.brainresbull.2004.04.011 - Maeda Y, 2017, BRAIN, V140, P914, DOI 10.1093/brain/awx015 - Mao JJ, 2021, JAMA ONCOL, V7, P720, DOI 10.1001/jamaoncol.2021.0310 - Mao N, 2010, HUM ECOL RISK ASSESS, V16, P801, DOI 10.1080/10807039.2010.501248 - Mawla I, 2021, ARTHRITIS RHEUMATOL, V73, P1318, DOI 10.1002/art.41620 - Mitra S, 2018, CURR PAIN HEADACHE R, V22, DOI 10.1007/s11916-018-0690-8 - Napadow V, 2005, HUM BRAIN MAPP, V24, P193, DOI 10.1002/hbm.20081 - National Institute for Health and Care Excellence, 2021, Guidelines. 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Pain Res. -PY 2023 -VL 16 -BP 3673 -EP 3691 -DI 10.2147/JPR.S422614 -PG 19 -WC Clinical Neurology -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Neurosciences & Neurology -GA X2BG5 -UT WOS:001096551900001 -PM 37942222 -OA Green Published, gold -DA 2025-07-11 -ER - -PT J -AU Khorshidi, MS - Merigó, JM - Beydoun, G -AF Khorshidi, Mohammad Sadegh - Merigo, Jose M. - Beydoun, Ghassan -TI Half a Century of Information Processing & Management: A bibliometric - retrospective -SO INFORMATION PROCESSING & MANAGEMENT -LA English -DT Article -DE Information Processing; Management; Bibliometrics; Web of Science; - Scopus; VOS viewer -ID TASK COMPLEXITY; RETRIEVAL; RELEVANCE; NETWORKS; ALGORITHM; SEEKING; - SCIENCE; INDEX -AB Established in 1963 under the title Information Storage and Retrieval, the journal adopted its current name, Information Processing & Management (IPM), in 1975, reflecting a broadening scope aligned with computational and cognitive developments in information science. This study uses data from Web of Science and Scopus databases to deliver a longitudinal, multi-perspective bibliometric and science mapping analysis of IPM's evolution from 1963 to 2023. Employing co-citation analysis, bibliographic coupling, keyword co-occurrence, and thematic mapping via VOSviewer and Bibliometrix, the analysis delineates the structural, conceptual, and topical transformation of the journal content. Co-citation networks uncover foundational cores in information retrieval, relevance theory, and evaluation methodologies, while also revealing temporal shifts toward natural language processing, deep learning, and social media analytics. Bibliographic coupling identifies coherent intellectual clusters centered on GNN-based recommendation systems, blockchain-secured infrastructures, and sentiment-aware retrieval frameworks. Keyword co-occurrence and topic evolution trajectories illustrate the journal's recent pivot toward transformer models, misinformation detection, ethical AI, and interdisciplinary convergence across cognitive science, machine learning, and computational linguistics. Regional co-word analysis underscores epistemological diversity and geographic differentiation across North America, Europe, and East Asia. Productivity and influence metrics highlight the ascent of East Asian institutions and the emergence of globally distributed citation impact. Finally, SciValbased topic and topic cluster analyses reveal the journal's role in advancing highly cited research (as measured by FWCI) in areas such as ABSA, multi-view clustering, and health informatics. 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Manage. -PD NOV -PY 2025 -VL 62 -IS 6 -AR 104238 -DI 10.1016/j.ipm.2025.104238 -PG 48 -WC Computer Science, Information Systems; Information Science & Library - Science -WE Science Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI) -SC Computer Science; Information Science & Library Science -GA 3PJ2D -UT WOS:001505825000002 -DA 2025-07-11 -ER - -PT J -AU Moradi, E - Gholampour, S - Gholampour, B -AF Moradi, Erfan - Gholampour, Sajad - Gholampour, Behzad -TI Past, present and future of sport policy: a bibliometric analysis of - International Journal of Sport Policy and Politics (2010-2022) -SO INTERNATIONAL JOURNAL OF SPORT POLICY AND POLITICS -LA English -DT Article -DE Bibliometric analysis; intellectual structure; International Journal of - Sport Policy and Politics; sport policy; science mapping; Scopus -ID RESEARCH AGENDA; SCIENCE; GENDER; IMPACT; GOVERNANCE; LEGITIMACY; - MANAGEMENT; LEADERSHIP; ORGANIZATIONS; SOCIOLOGY -AB Understanding a discipline's literature is essential to advance in that area. However, there has yet to be a study that summarises the current research on sport policy. Without a study of the topic, particularly one as extensive as the current one, where over 450 papers were evaluated, it is difficult for newcomers to the field and seasoned experts to have a firm grasp of all there is to know about it. Given this context, the current research is necessary and valuable because it is the first to provide insight into the effectiveness and intellectual framework of the sport policy literature selected by the International Journal of Sport Policy and Politics (IJSPP). This study used bibliometric techniques and indicators to analyse IJSPP publications from 2010 to 2022. The research data was collected from Scopus and analysed with bibliometrix and VOSviewer software. We found that the various components of the production (countries, institutions, and authors) in IJSPP work well in collaboration and over 82% of the research results from teamwork. The co-occurrence analysis of keywords comprises nine clusters, the co-citation analysis comprises four, and sport policy was the most significant cluster. Looking at niche topics in the future, sports diplomacy, social justice, elite sport policy, sport for development, and youth sport are just a few of the niche themes that have the potential to come up. This study will be helpful as a roadmap for researchers in different fields who are interested in such studies, as well as for editorial board members and those who work in sport policy and politics. -C1 [Moradi, Erfan] Tarbiat Modares Univ, Fac Humanities, Dept Sport Sci, Tehran, Iran. - [Gholampour, Sajad; Gholampour, Behzad] Parseh iMetrics Inst, Tehran, Iran. -C3 Tarbiat Modares University -RP Moradi, E (corresponding author), Tarbiat Modares Univ, Fac Humanities, Dept Sport Sci, Tehran, Iran. -EM erfan.moradi@modares.ac.ir -RI ; Moradi, Erfan/AAR-5863-2020; Gholampour, Sajad/AFP-5350-2022; - Gholampour, Behzad/AFP-5375-2022 -OI Gholampour, Sajad/0000-0002-1687-770X; Gholampour, - Behzad/0000-0003-4418-1117; Moradi, Erfan/0000-0002-6400-8058 -CR Aquilina D, 2010, INT J SPORT POLICY P, V2, P25, DOI 10.1080/19406941003634024 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Baier-Fuentes H, 2020, FRONT PSYCHOL, V11, DOI 10.3389/fpsyg.2020.01512 - Belfiore P., 2019, Sport Science, V12, P61 - 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A., 2021, Emerging Science Journal, V5, P96, DOI [10.28991/esj-2021-01261, DOI 10.28991/ESJ-2021-01261] - Zelenkov Y, 2023, MANAG SPORT LEIS, DOI 10.1080/23750472.2023.2200449 - Zhang B, 2017, EURASIA J MATH SCI T, V13, P5085, DOI 10.12973/eurasia.2017.00984a -NR 130 -TC 10 -Z9 10 -U1 5 -U2 23 -PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD -PI ABINGDON -PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND -SN 1940-6940 -EI 1940-6959 -J9 INT J SPORT POLICY P -JI Int. J. Sport Policy Polit. -PD OCT 2 -PY 2023 -VL 15 -IS 4 -BP 577 -EP 602 -DI 10.1080/19406940.2023.2228829 -EA JUN 2023 -PG 26 -WC Hospitality, Leisure, Sport & Tourism -WE Emerging Sources Citation Index (ESCI) -SC Social Sciences - Other Topics -GA W4PY6 -UT WOS:001015539900001 -DA 2025-07-11 -ER - -PT J -AU Hassan, T - Saleh, I -AF Hassan, Thowayeb - Saleh, Ibraheam -TI Tourism digital detox and digital-free tourism: What do we know? What do - we not know? Where should we be heading? -SO JOURNAL OF TOURISM FUTURES -LA English -DT Article; Early Access -DE Digital-free tourism; Digital detox; Tourist well-being; Technology - overload; Tourism experience; Tourism digitalization -ID BIBLIOMETRIC ANALYSIS; (DIS)CONNECTION; TECHNOLOGY; EXPERIENCE -AB PurposeWhile past research has begun exploring digital-free tourism, tourism digital detox and their benefits, no study to date has comprehensively mapped trends, findings and limitations across this growing body of literature. This study aims to conduct the first bibliometric analysis and systematic literature review to address this gap.Design/methodology/approachThis study utilized a mixed methodology of bibliometric analysis and systematic literature review. Structured search strings were applied to databases to identify relevant papers, which were screened according to inclusion criteria. Bibliometric analysis of included papers was performed using Bibliometrix, an R package enabling network visualization, statistical tests and science mapping. This allowed the identification of significant topics, theories, methods, citations and publication trends over time.FindingsThe results clearly show that factors previously lacking attention in past tourism research, such as the interplay between online and offline experiences during travel, are emerging as important determinants of travelers' well-being. This study outlines the current state of scholarship on managing technology's impacts on travelers' psychological and social needs. Specifically, we found limited research integrating how digital detox tools shape pre-trip planning, on-site activities and post-trip sharing of travel experiences.Originality/valueThis is the first study to comprehensively map trends and findings in digital-free tourism and tourism digital detox research using a blended bibliometric analysis and systematic literature review methodology. It offers vital direction toward strengthening theoretical understanding and supporting balanced connectivity and fulfillment for all tourists going forward. By addressing limitations, this research approach helps develop this area of scholarship in a unified manner. -C1 [Hassan, Thowayeb] King Faisal Univ, Coll Arts, Fac Art, Social Studies Department, Al Ahsa, Norway. - [Hassan, Thowayeb] Helwan Univ, Fac Tourism & Hotel Management, Helwan, Egypt. - [Saleh, Ibraheam] Helwan Univ, Fac Tourism & Hotel Management, Tourism Studies Dept, Helwan, Egypt. -C3 Egyptian Knowledge Bank (EKB); Helwan University; Egyptian Knowledge - Bank (EKB); Helwan University -RP Saleh, I (corresponding author), Helwan Univ, Fac Tourism & Hotel Management, Tourism Studies Dept, Helwan, Egypt. -EM Thassan@kfu.edu.sa; mahmoudibraheam580@gmail.com -OI saleh, mahmoud ibraheam/0000-0003-0436-5624 -FU Deanship of Scientific Research, Vice Presidency for Graduate Studies - and Scientific Research, King Faisal University, Saudi Arabia [029]; - National Institutes of Health Research (NIHR) [029] Funding Source: - National Institutes of Health Research (NIHR) -FX This work was supported by the Deanship of Scientific Research, Vice - Presidency for Graduate Studies and Scientific Research, King Faisal - University, Saudi Arabia [Grant No. 029]. -CR Arenas Escaso J. 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Tour. Futures -PD 2024 JUL 18 -PY 2024 -DI 10.1108/JTF-12-2023-0274 -EA JUL 2024 -PG 24 -WC Hospitality, Leisure, Sport & Tourism -WE Emerging Sources Citation Index (ESCI) -SC Social Sciences - Other Topics -GA YV1Z6 -UT WOS:001271182100001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Paul, J -AF Paul, Jyoti -TI A BIBLIOMETRIC ANALYSIS OF ROLE OF ICT IN SUSTAINABLE DEVELOPMENT GOALS -SO JIMS8M-THE JOURNAL OF INDIAN MANAGEMENT & STRATEGY -LA English -DT Article -DE ICT; SDG; Bibliometric analysis; Sustainability; Science mapping -AB Purpose: This bibliometric review is undertaken to explore the research work being pursued in the field of achieving the 2030 target of sustainable development goals with emphasis to role of ICT. Technology has been emphasised by United Nations as to play a key role as a facilitator in sustainable development goals. Design/methodology/approach: The data from Scopus database was used for Bibliometric analysis. .bib file was downloaded from the Scopus database for analysis. The extracted file has details viz. author's name, affiliation, article title, keywords, abstracts, and citation data. This file was used with Bibliometrix (R Studio). 163 results were used for analysis. These subject areas were selected to focus the data collection to the most relevant journal articles. The analysis using Biblioshiny was conducted on 19th Sep 2021.Findings: The findings revealed that publications around this area have enhanced considerably since 2015 and Norway is the most dominant country as per maximum citations. Furthermore, the thematic map shows that ICT and SDG and its varied related area are presently Basic themes of research i.e it is an area on which researchers have started working upon. Researchers are focussing on wide-ranging dimensions viz. tourism, smart cities, education etc. and exploring the role of ICT in fulfilment of 17 SDGs.Originality/value: The study is a novel attempt to find out the work being done in the area of role of ICT in achieving sustainable development goals. The study has taken a novel variable of ICT and sustainable development goals to find out the dimensions of work in this area. It has taken Scopus database to find prolific authors, dimensions in this area of research and prominent countries doing collaborative research in this domain. 2 S e sdp -C1 [Paul, Jyoti] Univ Delhi, Dyal Singh Coll, Dept Commerce, Lodhi Rd, New Delhi 110003, India. -C3 University of Delhi -RP Paul, J (corresponding author), Univ Delhi, Dyal Singh Coll, Dept Commerce, Lodhi Rd, New Delhi 110003, India. -CR [Anonymous], UN DOC DOWNL - Ashford NA, 2011, SUSTAINABILITY-BASEL, V3, P270, DOI 10.3390/su3010270 - Asongu SA, 2019, SUSTAIN DEV, V27, P647, DOI 10.1002/sd.1929 - Bibri SE, 2017, SUSTAIN CITIES SOC, V31, P183, DOI 10.1016/j.scs.2017.02.016 - Dervis H, 2019, J SCIENTOMETR RES, V8, P156, DOI 10.5530/jscires.8.3.32 - Glossing Stefan, 2019, SHARING VERSUS COLLA, DOI [10.1080/09669582.2018.1560455, DOI 10.1080/09669582.2018.1560455] - Mebratu D., 1998, ENVIRON IMPACT ASSES, V18, P493, DOI 10.1016/S0195-9255(98)00019-5 - Riehmann P, 2005, INFOVIS 05: IEEE SYMPOSIUM ON INFORMATION VISUALIZATION, PROCEEDINGS, P233, DOI 10.1109/INFVIS.2005.1532152 - Sachs JD, 2012, LANCET, V379, P2206, DOI 10.1016/S0140-6736(12)60685-0 - Tchamyou VS, 2019, TECHNOL FORECAST SOC, V139, P169, DOI 10.1016/j.techfore.2018.11.004 - UN, 2015, TRANSF OUR WORLD 203 - Vatananan-Thesenvitz R, 2019, SUSTAINABILITY-BASEL, V11, DOI 10.3390/su11205783 - World Commission on Environment and Development (WCED), 2021, OUR COMMON FUTURE - Xu ZS, 2021, TECHNOL FORECAST SOC, V170, DOI 10.1016/j.techfore.2021.120896 -NR 14 -TC 0 -Z9 0 -U1 0 -U2 21 -PU JAGANNATH INT MANAGEMENT SCH -PI NEW DELHI -PA OCF POCKET 9, SECTOR-B, VASANT KUNJ, NEW DELHI, 110 070, INDIA -SN 0973-9335 -EI 0973-9343 -J9 JIMS8M-J INDIAN MANA -JI JIMS8M-J. Indian Manag. Strategy -PD OCT-DEC -PY 2022 -VL 27 -IS 4 -BP 4 -EP 11 -DI 10.5958/0973-9343.2022.00024.2 -PG 8 -WC Management -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA 8R7IV -UT WOS:000928065200001 -DA 2025-07-11 -ER - -PT J -AU Singh, M - Nandan, T -AF Singh, Maneesha - Nandan, Tanuj -TI A bibliometric and visualization analysis of intertemporal choice: - origins, growth and future research avenues -SO JOURNAL OF MODELLING IN MANAGEMENT -LA English -DT Article -DE Intertemporal choice; Hyperbolic discounting; Bibliometric; Thematic - mapping; Co-citation analysis -ID TIME-INCONSISTENT PREFERENCES; DECISION-MAKING; SCIENTIFIC LITERATURE; - DISCOUNT RATES; PRESENT BIAS; SELF-CONTROL; DELAY; MODEL; TERM; - CONSUMPTION -AB Purpose - This study aims to conduct a bibliometric analysis on "intertemporal choice" behavior of individuals from journals in the Scopus database between 1957 and 2023. The research covered the data on the said topic since it first originated in the Scopus database and carried out performance analysis and content analysis of papers in the business management and finance disciplines. Design/methodology/approach - Bibliometric analysis, including science mapping and performance analysis, followed by content analysis of the papers of identified clusters, was conducted. Three clusters based on cocitation analysis and six themes (three major and three minor) were identified using the bibliometrix package in R studio. The content analysis of the papers in these clusters and themes have been discussed in this study, along with the thematic evolution of intertemporal choice research over the period of time, paving a way for future research studies. Findings - The review unpacks publication and citation trends of intertemporal choice behavior, the most significant authors, journals and papers along with the major clusters and themes of research based on cocitation and degree of centrality and relevance, respectively, i.e. discounting experiments and intertemporal choice, impulsivity, risk preference, time-inconsistent preference, etc. Originality/value - Over the past years, the research on "intertemporal choice" has flourished because of the increasing interest of researchers and scholars from different fields and the dynamic and pervasive nature of this topic. 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Manag. -PD OCT 11 -PY 2024 -VL 19 -IS 5 -BP 1644 -EP 1669 -DI 10.1108/JM2-07-2023-0157 -EA APR 2024 -PG 26 -WC Management -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA I2U4J -UT WOS:001196009400001 -DA 2025-07-11 -ER - -PT J -AU Mabele, MB - Kasongi, N - Nnko, H - Mwanyoka, I - Kiwango, WA - Makupa, E -AF Mabele, Mathew Bukhi - Kasongi, Ng'winamila - Nnko, Happiness - Mwanyoka, Iddi - Kiwango, Wilhelm Andrew - Makupa, Enock -TI Inequalities in the production and dissemination of biodiversity - conservation knowledge on Tanzania: A 50-year bibliometric analysis -SO BIOLOGICAL CONSERVATION -LA English -DT Review -DE Bibliometric analysis; Biodiversity conservation; Research trends; - North-South collaborations; Decolonising conservation; Tanzania -ID SCIENCE; TRENDS; WEB -AB Tanzania is a popular keyword in biodiversity conservation publications, but, trends in research collaborations, scientific knowledge production and authors' productivity remain underexplored. Using the Web of Science database and bibliometric analysis techniques, we fill this gap by examining the trends between 1972 and 2021. The database search produced 1517 records. We filtered the data using document types and subject categories as criteria. We used bibliometrix package in R software to analyse 1354 peer-reviewed publications. Through performance analysis, science mapping and network analysis, journal publications, author and institutional productivity, disciplinary focus, funding agencies and network of authorship and institutional collaborations are identified. Whereas African Journal of Ecology, PLoS One and Biological Conservation top the scientific production list, Biological Conservation, Conservation Biology and Oryx top the citation list. Major research inequalities are revealed where, European and North American centricity dominates in author productivity (number of papers, total citations and h-index), author collaborations networks and research funding agencies. Out of the top 20 highly cited papers, eleven had no Tanzanian author. The list had only two papers with Tanzanians as first authors. We observed a proliferation of international researchers and decreased productivity of local researchers in the last 30 years. Organisations from Europe and North America provided much of the research funding in Tanzania. This is possibly one of the first attempts to illustrate empirically how production and dissemination of conservation knowledge are entrenched in unequal structures at a country level. We thus contribute to the burgeoning literature on decolonisation of conservation research, by proposing five practical areas to dismantle the unequal system of knowledge production. -C1 [Mabele, Mathew Bukhi; Kasongi, Ng'winamila; Mwanyoka, Iddi; Kiwango, Wilhelm Andrew; Makupa, Enock] Univ Dodoma, Dept Geog & Environm Studies, Dodoma, Tanzania. - [Nnko, Happiness] Univ Dodoma, Dept Biol, Dodoma, Tanzania. - [Mabele, Mathew Bukhi] Univ Cambridge, Ctr African Studies, Cambridge, England. -C3 University of Cambridge -RP Mabele, MB (corresponding author), Univ Dodoma, Dept Geog & Environm Studies, Dodoma, Tanzania.; Mabele, MB (corresponding author), Univ Cambridge, Ctr African Studies, Cambridge, England. -EM mathew.bukhi@udom.ac.tz -RI Kiwango, Wilhelm/JGD-2307-2023; Mabele, Mathew Bukhi/P-1116-2016; - Mabele, Mathew/AHD-7633-2022 -OI Mabele, Mathew Bukhi/0000-0002-2460-2415; Kasongi, - Ng'winamila/0000-0003-1990-7844; Kiwango, Wilhelm - Andrew/0000-0002-4058-1853 -CR Aleixandre-Benavent R, 2018, LAND USE POLICY, V72, P293, DOI 10.1016/j.landusepol.2017.12.060 - [Anonymous], 2018, LANCET GLOB HEALTH, V6, pE593, DOI 10.1016/S2214-109X(18)30239-0 - Apostolopoulou E, 2021, GEOFORUM, V124, P236, DOI 10.1016/j.geoforum.2021.05.006 - Asase A, 2022, CONSERV SCI PRACT, V4, DOI 10.1111/csp2.517 - Barabási AL, 1999, SCIENCE, V286, P509, DOI 10.1126/science.286.5439.509 - Bennett NJ, 2017, BIOL CONSERV, V205, P93, DOI 10.1016/j.biocon.2016.10.006 - Binka F, 2005, TROP MED INT HEALTH, V10, P207, DOI 10.1111/j.1365-3156.2004.01373.x - Brockington D., 2022, Contested Sustainability: The Political Ecology of Conservation and Development in Tanzania, P287 - Collins YA, 2021, J POLIT ECOL, V28, P1 - Corbera E, 2021, ORYX, V55, P868, DOI 10.1017/S0030605320000940 - Dahdouh-Guebas F, 2003, SCIENTOMETRICS, V56, P329, DOI 10.1023/A:1022374703178 - de Vos A., 2020, Sci Am - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Genda PA, 2022, CONSERV SCI PRACT, V4, DOI 10.1111/csp2.12677 - Hicks CC, 2016, SCIENCE, V352, P38, DOI 10.1126/science.aad4977 - Hsieh HF, 2005, QUAL HEALTH RES, V15, P1277, DOI 10.1177/1049732305276687 - Huang L, 2020, J CLEAN PROD, V252, DOI 10.1016/j.jclepro.2019.119908 - Leader-Williams N., 2011, Trade-offs in Conservation: Deciding What to Save - Li N, 2018, RESOUR CONSERV RECY, V130, P109, DOI 10.1016/j.resconrec.2017.11.008 - Liu XJ, 2011, BIODIVERS CONSERV, V20, P807, DOI 10.1007/s10531-010-9981-z - Ministry of Environment, 2015, NAT BIOD STRAT ACT P - Mongeon P, 2016, SCIENTOMETRICS, V106, P213, DOI 10.1007/s11192-015-1765-5 - Myers N, 2000, NATURE, V403, P853, DOI 10.1038/35002501 - Nuñez MA, 2021, TRENDS ECOL EVOL, V36, P766, DOI 10.1016/j.tree.2021.06.004 - Overland I, 2022, CLIM DEV, V14, P705, DOI 10.1080/17565529.2021.1976609 - Pototsky PC, 2021, ORYX, V55, P924, DOI 10.1017/S0030605320000046 - PRITCHARD A, 1969, J DOC, V25, P348 - R Core Team, 2022, R LANG ENV STAT COMP - Rands MRW, 2010, SCIENCE, V329, P1298, DOI 10.1126/science.1189138 - Stefanoudis PV, 2021, CURR BIOL, V31, pR184, DOI [10.1016/j.cub.2020.12.025.#mm6z, 10.1016/j.cub.2021.01.029] - Tilley E, 2021, J AFR CULT STUD, V33, P538, DOI 10.1080/13696815.2021.1884972 - Trisos CH, 2021, NAT ECOL EVOL, V5, P1205, DOI 10.1038/s41559-021-01460-w - Urassa M, 2021, NAT HUM BEHAV, V5, P668, DOI 10.1038/s41562-021-01076-x - Wang BJ, 2021, ECOL INDIC, V125, DOI 10.1016/j.ecolind.2021.107449 - Wang Q, 2016, J INFORMETR, V10, P347, DOI 10.1016/j.joi.2016.02.003 - Wang ZH, 2018, J CLEAN PROD, V199, P1072, DOI 10.1016/j.jclepro.2018.06.183 - Wilson KA, 2016, PLOS BIOL, V14, DOI 10.1371/journal.pbio.1002413 - Zhang XM, 2019, PLOS ONE, V14, DOI 10.1371/journal.pone.0210707 -NR 38 -TC 21 -Z9 21 -U1 1 -U2 19 -PU ELSEVIER SCI LTD -PI London -PA 125 London Wall, London, ENGLAND -SN 0006-3207 -EI 1873-2917 -J9 BIOL CONSERV -JI Biol. Conserv. -PD MAR -PY 2023 -VL 279 -AR 109910 -DI 10.1016/j.biocon.2023.109910 -EA JAN 2023 -PG 14 -WC Biodiversity Conservation; Ecology; Environmental Sciences -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Biodiversity & Conservation; Environmental Sciences & Ecology -GA M0RI1 -UT WOS:001027280000001 -DA 2025-07-11 -ER - -PT J -AU Wani, JA - Ganaie, SA - Rehman, IU -AF Wani, Javaid Ahmad - Ganaie, Shabir Ahmad - Rehman, Ikhlaq Ur -TI Mapping research output on library and information science research - domain in South Africa: a bibliometric visualisation -SO INFORMATION DISCOVERY AND DELIVERY -LA English -DT Article -DE Library and information science; Bibliometrics; Science mapping; - VOSviewer; Bibliometrix-R; South Africa -ID ORGANIC-CHEMISTRY RESEARCH; RESEARCH COLLABORATION; PUBLICATION - PATTERNS; INTERNATIONAL COLLABORATION; SUSTAINABLE DEVELOPMENT; ACADEMIC - LIBRARIANS; CITATION ANALYSIS; WATER RESEARCH; TRENDS; FIELD -AB Purpose The purpose of this study is to examine the research output on "library and information science" (LIS) research domain in South Africa. It also highlights the top LIS research organisations, authors, journals, collaboration types and commonly used keywords. This research will aid in the identification of emerging concepts, trends and advances in this subject. Design/methodology/approach The Web of Science (WoS), an indexing and abstracting database, served as a tool for bibliographical data. By applying advanced search features, the authors curated data from 1989 to 2021 through the WoS subject category WC = (Information Science & Library Science), limiting the scope to the region, CU = (South Africa), which resulted in 1,034 articles. Moreover, the research focuses on science mapping using the R package for reliable analysis. Findings The findings reveal that the publications have considerably grown over time, indicating significant attention among researchers in LIS. The findings indicate the critical operator's performance, existing thematic choices and subsequent research opportunities. The primary topical fields of study that emerged from the bibliometric analysis are impact, information, science, model, management, technology, knowledge and education. Pouris and Fourie are the most productive citations, h-index and g-index. The influential institute was The University of Pretoria. Research limitations/implications The use of the WoS database for data collecting limits this study. Because the WoS was the only citation and abstract database used in this study, bibliometric investigations using other citation and abstract databases like "Scopus", "Google Scholar" and "Dimension" could be interesting. This study presented a bibliometric summary; nevertheless, a systematic and methodical examination of highly cited LIS research publications could throw more light on the subject. Practical implications This paper gives valuable information about recent scientific advancements in the LIS and emerging future academic subject prospects. Furthermore, this research work will serve as a reference for researchers in various areas to analyse the evolution of scholarly literature on a particular topic over time. Originality/value By identifying the standard channels of study in the LIS discipline, and the essential journals, publications, nations, institutions, authors, data sources and networks in this subject, this bibliometric mapping and visualisation provide new perspectives into academic performance. This paper also articulates future research directions in this realm of knowledge. 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Deliv. -PD APR 7 -PY 2023 -VL 51 -IS 2 -BP 194 -EP 212 -DI 10.1108/IDD-10-2021-0115 -EA OCT 2022 -PG 19 -WC Information Science & Library Science -WE Emerging Sources Citation Index (ESCI) -SC Information Science & Library Science -GA D3UZ1 -UT WOS:000869084800001 -DA 2025-07-11 -ER - -PT J -AU Bitar, F - Arabi, M - Bulbul, Z - Nemer, G - Jassar, Y - Bitar, FF - Sater, ZA -AF Bitar, Fouad - Arabi, Mariam - Bulbul, Ziad - Nemer, Georges - Jassar, Yehya - Bitar, Fadi F. - Abdul Sater, Zahi -TI Congenital heart disease research landscape in the Arab world: a 25-year - bibliometric review -SO FRONTIERS IN CARDIOVASCULAR MEDICINE -LA English -DT Review -DE research; Arab countries; limited resource countries; developing and - developed countries; congenital heart disease; pediatric cardiology; - children -AB BackgroundWhile research on congenital heart disease has been extensively conducted worldwide, comprehensive studies from developing countries and the Arab world remain scarce.AimThis study aims to perform a bibliometric review of research on congenital heart disease in the Arab world from 1997 to 2022.MethodsWe analyzed data from the Web of Science, encompassing various aspects such as topics, countries, research output, citations, authors, collaborations, and affiliations. This comprehensive science mapping analysis was done using the R statistical software's Bibliometrix Package.ResultsThe research output from Arab countries over the 25 years showed an average annual growth rate of 11.5%. However, Arab countries exhibited lower research productivity than the United States and Europe, with a 24-fold difference. There was substantial variation in research output among 22 Arab countries, with five countries contributing to 78% of the total publications. Most of the published research was clinical, with limited innovative contributions and a preference for regional journals. High-income Arab countries displayed higher research productivity and citation rates than their low-income developing counterparts. Despite being categorized as upper-middle-income, post-conflict countries exhibited low research productivity. About one-quarter of the published articles (26%) resulted from collaborative efforts among multiple countries, with the United States being the most frequent collaborator. Enhanced research productivity and impact output were strongly associated with increased international cooperation.ConclusionResearch productivity in the Arab region closely correlates with a country's GDP. Success hinges on governmental support, funding, international collaboration, and a clear research vision. These findings offer valuable insights for policymakers, educational institutions, and governments to strengthen research programs and nurture a research culture. -C1 [Bitar, Fouad; Arabi, Mariam; Bulbul, Ziad; Bitar, Fadi F.] Amer Univ Beirut, Med Ctr, Dept Pediat & Adolescent Med, Beirut, Lebanon. - [Arabi, Mariam; Bulbul, Ziad; Jassar, Yehya; Bitar, Fadi F.] Amer Univ Beirut, Childrens Heart Ctr, Med Ctr, Dept Pediat & Adolescent Med, Beirut, Lebanon. - [Nemer, Georges] Hamad Bin Khalifa Univ, Coll Hlth & Life Sci, Genom & Precis Med GPM, Doha, Qatar. - [Abdul Sater, Zahi] Phoenicia Univ, Coll Publ Hlth, Dept Publ Hlth, Mazraat El Daoudiyeh, Lebanon. - [Abdul Sater, Zahi] Amer Univ Beirut, Global Hlth Inst, Beirut, Lebanon. -C3 American University of Beirut; American University of Beirut; Qatar - Foundation (QF); Hamad Bin Khalifa University-Qatar; American University - of Beirut -RP Bitar, FF (corresponding author), Amer Univ Beirut, Med Ctr, Dept Pediat & Adolescent Med, Beirut, Lebanon.; Bitar, FF (corresponding author), Amer Univ Beirut, Childrens Heart Ctr, Med Ctr, Dept Pediat & Adolescent Med, Beirut, Lebanon.; Sater, ZA (corresponding author), Phoenicia Univ, Coll Publ Hlth, Dept Publ Hlth, Mazraat El Daoudiyeh, Lebanon.; Sater, ZA (corresponding author), Amer Univ Beirut, Global Hlth Inst, Beirut, Lebanon. -EM fbitar@aub.edu.lb; zahi.abdulsater@pu.edu.lb -RI Nemer, Georges/ABB-5117-2020; Abdul-sater, Zahi/AAM-6543-2020 -FU The author(s) declare that no financial support was received for the - research, authorship, and/or publication of this article. -FX No Statement Available -CR Aburawi E., 2013, Ibnosina J Med Biomed Sci, V5, P1, DOI [10.4103/1947-489X.210518, DOI 10.4103/1947-489X.210518] - Albesher N, 2022, GENES-BASEL, V13, DOI 10.3390/genes13020354 - AlBloushi AF, 2022, J INFECT PUBLIC HEAL, V15, P709, DOI 10.1016/j.jiph.2022.05.013 - Alzyoud R, 2023, PEDIATR CARDIOL, V44, P1277, DOI 10.1007/s00246-023-03166-1 - [Anonymous], 1981, wikipedia - [Anonymous], 2016, Wikipedia - [Anonymous], 2023, stemcellsciencenewsNovember 27 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Balachandran R, 2015, ANN CARD ANAESTH, V18, P52, DOI 10.4103/0971-9784.148322 - Chadegani A.A., 2013, arXiv, DOI [10.5539/ass.v9n5p18, DOI 10.5539/ASS.V9N5P18] - Dearani Joseph A, 2010, Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu, V13, P35, DOI 10.1053/j.pcsu.2010.02.001 - Eken S., 1996, Growth and Stability in the Middle East and North Africa, P1, DOI [10.5089/9781557755650.054, DOI 10.5089/9781557755650.054] - El Rassi I, 2020, FRONT PEDIATR, V8, DOI 10.3389/fped.2020.00357 - elibrary.imf, About Us - Farhat T, 2013, PEDIATR CARDIOL, V34, P375, DOI 10.1007/s00246-012-0466-6 - Jonas Richard A, 2008, Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu, P3, DOI 10.1053/j.pcsu.2007.12.001 - Latif R, 2015, J FAM COMMUNITY MED, V22, P25, DOI 10.4103/2230-8229.149583 - Liang YM, 2023, FRONT CARDIOVASC MED, V10, DOI 10.3389/fcvm.2023.1183606 - Liu YJ, 2019, INT J EPIDEMIOL, V48, P455, DOI 10.1093/ije/dyz009 - Murala JSK, 2019, FRONT PEDIATR, V7, DOI 10.3389/fped.2019.00214 - Nabulsi MM, 2003, AM J MED GENET A, V116A, P342, DOI 10.1002/ajmg.a.10020 - Saxena A, 2019, CHILDREN-BASEL, V6, DOI 10.3390/children6020034 - van der Linde D, 2011, J AM COLL CARDIOL, V58, P2241, DOI 10.1016/j.jacc.2011.08.025 -NR 23 -TC 0 -Z9 0 -U1 0 -U2 5 -PU FRONTIERS MEDIA SA -PI LAUSANNE -PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND -SN 2297-055X -J9 FRONT CARDIOVASC MED -JI Front. Cardiovasc. Med. -PD JAN 11 -PY 2024 -VL 10 -AR 1332291 -DI 10.3389/fcvm.2023.1332291 -PG 10 -WC Cardiac & Cardiovascular Systems -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Cardiovascular System & Cardiology -GA FU2A9 -UT WOS:001148292000001 -PM 38274308 -OA Green Published, gold -DA 2025-07-11 -ER - -PT J -AU Shahait, M - Ibrahim, S - Baqain, L - Abdul-Sater, Z -AF Shahait, Mohammed - Ibrahim, Sarah - Baqain, Laith - Abdul-Sater, Zahi -TI Bibliometric analysis of focal therapy in prostate cancer research -SO BJUI COMPASS -LA English -DT Article -DE bibliometric; focal therapy; prostate cancer -ID ACTIVE SURVEILLANCE -AB IntroductionThe use of focal therapies for prostate cancer (PCa) has soared, as it controls disease and is associated with minimal side effects. Bibliometric analysis examines the global research landscape on any topic to identify gaps in the research and areas for improvement and prioritize future research efforts. This study aims to examine the research outputs and trends and collaboration landscape in the field of focal therapy for PCa on a global scale.MethodsWe searched Medline, PubMed and Scopus for peer-reviewed publications on our research topic using controlled keywords. Search results were limited to the period between 1980 and 2022, screened for duplicates and then included in our study based on prespecified eligibility criteria. The Bibliometrix Package was used for comprehensive science mapping analysis of co-authorship, co-citation and co-occurrence analysis of countries, institutions, authors, references and keywords in this field.ResultsThis analysis included 2578 research articles. The annual scientific production increased from one article in 1982 to 143 in 2022 (13.21%). The average citation per year was incrementally increasing, and these documents were cited around 32.52 times. The documents included in this analysis were published in 633 sources. The international collaboration index was 22.7. In total, 6280 author keywords were identified. The most used keywords were 'prostate cancer', 'focal therapy', 'prostate' and 'photodynamic therapy'.ConclusionThis bibliometric analysis has provided a comprehensive review of focal therapy in PCa research, highlighting both the significant growth in the field and the existing gaps that require further exploration. The study points to the need for more diverse international collaboration and exploration of various treatment modalities within the context of focal therapy. -C1 [Shahait, Mohammed] Clemenceau Med Ctr, Dept Surg, Dubai, U Arab Emirates. - [Ibrahim, Sarah] Amer Univ Beirut, Global Hlth Inst, Beirut, Lebanon. - [Baqain, Laith] Univ Jordan, Fac Med, Amman, Jordan. - [Abdul-Sater, Zahi] Phoenicia Univ, Coll Publ Hlth, Mazraat El Daoudiyeh, Lebanon. - [Abdul-Sater, Zahi] Phoenicia Univ, Mazraat El Daoudiyeh, Lebanon. -C3 American University of Beirut; University of Jordan -RP Abdul-Sater, Z (corresponding author), Phoenicia Univ, Mazraat El Daoudiyeh, Lebanon. -EM zahi.abdulsater@pu.edu.lb -RI Abdul-sater, Zahi/AAM-6543-2020; Shahait, Mohammed/AAQ-4988-2020; - Shahait, Mohammed/I-4752-2018 -OI Shahait, Mohammed/0000-0003-2609-5629; Baqain, - Laith/0000-0002-1486-1106; Abdul-Sater, Zahi/0000-0002-0340-1657 -CR [Anonymous], Processing: Principles and Applications, DOI DOI 10.1002/0471745790 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Awada H, 2023, ARAB J UROL, V21, P1, DOI 10.1080/2090598X.2022.2152237 - Eckhouse S, 2008, MOL ONCOL, V2, P20, DOI 10.1016/j.molonc.2008.03.007 - El Rassi R, 2018, J GLOB HEALTH, V8, DOI 10.7189/jogh.08.020411 - Hilal L, 2015, CLIN GENITOURIN CANC, V13, P505, DOI 10.1016/j.clgc.2015.05.010 - Hirsch JE, 2005, P NATL ACAD SCI USA, V102, P16569, DOI 10.1073/pnas.0507655102 - Jemal A, 2007, CA-CANCER J CLIN, V57, P43, DOI 10.3322/canjclin.57.1.43 - Kinsella N, 2018, TRANSL ANDROL UROL, V7, P83, DOI 10.21037/tau.2017.12.24 - Latif R, 2015, J FAM COMMUNITY MED, V22, P25, DOI 10.4103/2230-8229.149583 - Ma CQ, 2021, FRONT ONCOL, V10, DOI 10.3389/fonc.2020.627891 - Nassereldine H., PANCREATIC CANC MENA - Ong S, 2023, BJU INT, V131, P20, DOI 10.1111/bju.15883 - Sanda MG, 2018, J UROLOGY, V199, P683, DOI 10.1016/j.juro.2017.11.095 - Thompson Ian M, 2012, Am Soc Clin Oncol Educ Book, pe35, DOI 10.14694/EdBook_AM.2012.32.e35 - Uthman OA, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0078517 - Vaudano E, 2020, HANDB EXP PHARMACOL, V257, P383, DOI 10.1007/164_2019_293 - Venderbos LDF, 2015, PSYCHO-ONCOLOGY, V24, P348, DOI 10.1002/pon.3657 - Wang J, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0117727 - World Health Organization, 2019, LIST I FUNDING CANC -NR 20 -TC 0 -Z9 0 -U1 1 -U2 5 -PU WILEY -PI HOBOKEN -PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA -SN 2688-4526 -J9 BJUI COMPASS -JI BJUI Compass -PD JUN -PY 2024 -VL 5 -IS 6 -BP 602 -EP 609 -DI 10.1002/bco2.353 -EA MAR 2024 -PG 8 -WC Urology & Nephrology -WE Emerging Sources Citation Index (ESCI) -SC Urology & Nephrology -GA UD4O6 -UT WOS:001185920100001 -PM 38873353 -OA gold, Green Published -DA 2025-07-11 -ER - -PT J -AU Damayanti, AD - Gani, H - Feng, ZP - Gani, H - Zuhriyah, S - Djabir, SN - Wardani, NI -AF Damayanti, Annisa Dwi - Gani, Hamdan - Zhipeng, Feng - Gani, Helmy - Zuhriyah, Sitti - Djabir, St. Nurhayati - Wardani, Nur Ilmiyanti -TI Bibliometric and Content Analysis of Large Language Models Research in - Software Engineering: The Potential and Limitation in Software - Engineering -SO INTERNATIONAL JOURNAL OF ADVANCED COMPUTER SCIENCE AND APPLICATIONS -LA English -DT Article -DE -Large Language Models; LLM; software engineering; bibliometric; content - analysis -AB Language Models (LLM) is a type of artificial neural network that excels at language-related tasks. The advantages and disadvantages of using LLM in software engineering are still being debated, but it is a tool that can be utilized in software engineering. This study aimed to analyze LLM studies in software engineering using bibliometric and content analysis. The study data were retrieved from Web of Science and Scopus. The data were analyzed using two popular bibliometric approaches: bibliometric and content analysis. VOS Viewer and Bibliometrix software were used to conduct the bibliometric analysis. The bibliometric analysis was performed using science mapping and performance analysis approaches. Various bibliometric data, including the most frequently referenced publications, journals, and nations, were evaluated and presented. Then, the synthetic knowledge method was utilized for content analysis. This study examined 235 papers, with 836 authors contributing. The publications were published in 123 different journals. The average number of citations per publication is 1.44. Most publications were published in China and the United States emerging as the leading countries. It was discovered that international collaboration on the issue was inadequate. The most often used keywords in the publications were "software design," "code (symbols)," and "code generation." Following the content analysis, three themes emerged: 1) Integration of LLM into software engineering education, 2) application of LLM in software engineering, and 3) potential and limitation of LLM in software engineering. The results of this study are expected to provide researchers and academics with insights into the current state of LLM in software engineering research, allowing them to develop future conclusions. -C1 [Damayanti, Annisa Dwi] Hasanuddin University, Faculty of Engineering, Department of Environmental Engineering, Makassar, Indonesia. - [Gani, Hamdan; Djabir, St. Nurhayati] Department of Machinery Automation System, ATI Makassar Polytechnic, Makassar, Indonesia. - [Zhipeng, Feng] Hangzhou Normal University, School of Culture Creativity and Media, Hangzhou, Zhejiang, China. - [Gani, Helmy] Makassar College of Health Sciences, Faculty of Public Health Occupational Health and Safety, Department of Industrial Hygiene, Occupational Health and Safety, Indonesia. - [Zuhriyah, Sitti] Universitas Handayani Makassar, Department of Computer System, Makassar, Indonesia. - Institut Teknologi dan Bisnis Nobel Indonesia, Department of Information Systems and Technology, Jl. 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Considering the present scenario of COVID-19 outbreak and its impact on humankind, holistic remedies with respect to herbal medicine validated from ethnopharmacological rationale are now targeting approaches globally as a preventive care against SARS-CoV-2. Aim: This review is primarily focused on to deliver a concise fact of the coronaviridae family, pathophysiology, mechanism of action, ethnopharmacological validated Indian herbs for inhibiting the virus with possible targets. Experimental procedure: In this study, science mapping tool Bibliometrix R-package was used to perform bibliometric analysis and building data matrices for keywords co-occurrence investigation, country-wise scientific production; collaboration between the countries worldwide, co-word analysis on topic "keywords associated with SARS-CoV-2 and medicinal plants". 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Res. -PD OCT-DEC -PY 2021 -VL 13 -IS 4 -BP 173 -EP 191 -DI 10.5530/pres.13.4.10 -PG 19 -WC Pharmacology & Pharmacy -WE Emerging Sources Citation Index (ESCI) -SC Pharmacology & Pharmacy -GA ZB5ZR -UT WOS:000756920500001 -OA hybrid -DA 2025-07-11 -ER - -PT J -AU Martynov, I - Klima-Frysch, J - Schoenberger, J -AF Martynov, Illya - Klima-Frysch, Jessica - Schoenberger, Joachim -TI A scientometric analysis of neuroblastoma research -SO BMC CANCER -LA English -DT Article -DE Neuroblastoma; Scientometrics; Research performance; Children; Network - analysis -ID SCIENCE; PLOIDY; INDEX -AB Background Thousands of research articles on neuroblastoma have been published over the past few decades; however, the heterogeneity and variable quality of scholarly data may challenge scientists or clinicians to survey all of the available information. Hence, holistic measurement and analyzation of neuroblastoma-related literature with the help of sophisticated mathematical tools could provide deep insights into global research performance and the collaborative architectonical structure within the neuroblastoma scientific community. In this scientometric study, we aim to determine the extent of the scientific output related to neuroblastoma research between 1980 and 2018. Methods We applied novel scientometric tools, including Bibliometrix R package, biblioshiny, VOSviewer, and CiteSpace IV for comprehensive science mapping analysis of extensive bibliographic metadata, which was retrieved from the Web of ScienceTM Core Collection database. Results We demonstrate the enormous proliferation of neuroblastoma research during last the 38 years, including 12,435 documents published in 1828 academic journals by 36,908 authors from 86 different countries. These documents received a total of 316,017 citations with an average citation per document of 28.35 +/- 7.7. We determine the proportion of highly cited and never cited papers, "occasional" and prolific authors and journals. Further, we show 12 (13.9%) of 86 countries were responsible for 80.4% of neuroblastoma-related research output. Conclusions These findings are crucial for researchers, clinicians, journal editors, and others working in neuroblastoma research to understand the strengths and potential gaps in the current literature and to plan future investments in data collection and science policy. This first scientometric study of global neuroblastoma research performance provides valuable insight into the scientific landscape, co-authorship network architecture, international collaboration, and interaction within the neuroblastoma community. -C1 [Martynov, Illya; Klima-Frysch, Jessica; Schoenberger, Joachim] Univ Hosp Freiburg, Dept Pediat Surg, Freiburg, Germany. - [Martynov, Illya] Univ Leipzig, Dept Pediat Surg, Leipzig, Germany. -C3 University of Freiburg; Leipzig University -RP Martynov, I (corresponding author), Univ Hosp Freiburg, Dept Pediat Surg, Freiburg, Germany.; Martynov, I (corresponding author), Univ Leipzig, Dept Pediat Surg, Leipzig, Germany. -EM illya.martynov@medizin.uni-leipzig.de -RI Martynov, Illya/AAS-1006-2020 -OI Martynov, Illya/0000-0003-4400-302X -CR [Anonymous], 1991, Applied Stochastic Models and Data Analysis, DOI [DOI 10.1002/ASM.3150070208, 10.1002/asm.3150070208] - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Begum M, 2018, EUR J CANCER, V100, P75, DOI 10.1016/j.ejca.2018.04.017 - Bresler SC, 2014, CANCER CELL, V26, P682, DOI 10.1016/j.ccell.2014.09.019 - BRODEUR GM, 1993, J CLIN ONCOL, V11, P1466, DOI 10.1200/JCO.1993.11.8.1466 - Brodeur GM, 2003, NAT REV CANCER, V3, P203, DOI 10.1038/nrc1014 - Butrous G, 2008, ANN THORAC MED, V3, P79, DOI 10.4103/1817-1737.41913 - Cabral Bernardo Pereira, 2018, Oncotarget, V9, P30474, DOI 10.18632/oncotarget.25730 - Cheung NKV, 2013, NAT REV CANCER, V13, P397, DOI 10.1038/nrc3526 - Decarolis B, 2016, BMC CANCER, V16, DOI 10.1186/s12885-016-2513-9 - Dwivedi S, 2017, CURR SCI INDIA, V112, P1814, DOI 10.18520/cs/v112/i09/1814-1821 - Esiashvili N, 2009, CURR PROB CANCER, V33, P333, DOI 10.1016/j.currproblcancer.2009.12.001 - Finch A, 2012, CHANDOS PUBL SER, P243 - Flotte TR, 2017, HUM GENE THER, V28, P1, DOI 10.1089/hum.2016.29037.trf - Glynn RW, 2010, BREAST CANCER RES, V12, DOI 10.1186/bcr2795 - Gostin LO, 2009, HASTINGS CENT REP, V39, P11, DOI 10.1353/hcr.0.0114 - Greene M, 2007, NATURE, V450, P1165, DOI 10.1038/4501165a - Groneberg-Kloft Beatrix, 2008, Health Res Policy Syst, V6, P6, DOI 10.1186/1478-4505-6-6 - Hirsch JE, 2005, P NATL ACAD SCI USA, V102, P16569, DOI 10.1073/pnas.0507655102 - Johnsen JI, 2018, PHARMACOL RES, V131, P164, DOI 10.1016/j.phrs.2018.02.023 - Laverdière C, 2009, JNCI-J NATL CANCER I, V101, P1131, DOI 10.1093/jnci/djp230 - LAYFIELD LJ, 1995, J SURG ONCOL, V59, P21, DOI 10.1002/jso.2930590107 - Lee JW, 2018, PEDIATR BLOOD CANCER, V65, DOI 10.1002/pbc.27257 - LOOK AT, 1991, J CLIN ONCOL, V9, P581, DOI 10.1200/JCO.1991.9.4.581 - Maris JM, 2010, NEW ENGL J MED, V362, P2202, DOI 10.1056/NEJMra0804577 - Matthay KK, 2016, NAT REV DIS PRIMERS, V2, DOI 10.1038/nrdp.2016.78 - MERTON RK, 1968, SCIENCE, V159, P56, DOI 10.1126/science.159.3810.56 - Modak S, 2010, CANCER TREAT REV, V36, P307, DOI 10.1016/j.ctrv.2010.02.006 - Nguyen R., 2019, NEUROBLASTOMA MOL ME, P43, DOI 10.1016/B978-0-12-812005-7.00003-5 - Oeffinger KC, 2006, NEW ENGL J MED, V355, P1572, DOI 10.1056/NEJMsa060185 - Park JR, 2013, PEDIATR BLOOD CANCER, V60, P985, DOI 10.1002/pbc.24433 - Pinto NR, 2015, J CLIN ONCOL, V33, P3008, DOI 10.1200/JCO.2014.59.4648 - Rosson NJ, 2017, GLOBALIZATION HEALTH, V13, DOI 10.1186/s12992-017-0298-5 - Smith MA, 2010, J CLIN ONCOL, V28, P2625, DOI 10.1200/JCO.2009.27.0421 - Spix C, 2006, EUR J CANCER, V42, P2081, DOI 10.1016/j.ejca.2006.05.008 - Syrimi E, 2020, JCO GLOB ONCOL, V6, P9, DOI 10.1200/JGO.19.00227 - Trigg RM, 2018, CANCERS, V10, DOI 10.3390/cancers10040113 - Valentijn LJ, 2012, P NATL ACAD SCI USA, V109, P19190, DOI 10.1073/pnas.1208215109 - Van Arendonk KJ, 2019, CHILDREN-BASEL, V6, DOI 10.3390/children6010012 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Whittle SB, 2017, EXPERT REV ANTICANC, V17, P369, DOI 10.1080/14737140.2017.1285230 - Yu AL, 2010, NEW ENGL J MED, V363, P1324, DOI 10.1056/NEJMoa0911123 -NR 42 -TC 41 -Z9 42 -U1 2 -U2 52 -PU BMC -PI LONDON -PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND -EI 1471-2407 -J9 BMC CANCER -JI BMC Cancer -PD MAY 29 -PY 2020 -VL 20 -IS 1 -AR 486 -DI 10.1186/s12885-020-06974-3 -PG 10 -WC Oncology -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Oncology -GA LU7WH -UT WOS:000537960500004 -PM 32471384 -OA gold, Green Published, Green Submitted -DA 2025-07-11 -ER - -PT J -AU Kumar, S - Pandey, N - Burton, B - Sureka, R -AF Kumar, Satish - Pandey, Nitesh - Burton, Bruce - Sureka, Riya -TI Research patterns and intellectual structure of Managerial Auditing - Journal: a retrospective using bibliometric analysis during - 1986-2019 -SO MANAGERIAL AUDITING JOURNAL -LA English -DT Article -DE Citation analysis; Scopus; Keywords analysis; Bibliometrix; Managerial - Auditing Journal; h-index; VOSviewer; Gephi -ID EARNINGS MANAGEMENT; INTERNAL AUDIT; CITATION ANALYSIS; QUALITY; - COMMITTEE; PERCEPTIONS; ARTICLES; NETWORK; AUTHOR; EGYPT -AB Purpose - The Managerial Auditing Journal (MAJ) started publication in 1986 and celebrates its 35th year of publication in 2020. The purpose of this study is to provide a detailed bibliometric analysis of the journal's primary trends and themes between 1986 and 2019. - Design/methodology/approach - This study uses the Scopus database to analyse the most prolific authors in the MAJ along with their affiliated institutions and countries; the work also identifies the MAJ articles cited most often by other journals. A range of bibliometric devices is applied to analyse the publication and citation structure of MAJ, alongside performance analysis and science mapping tools. The study also provides a detailed inter-temporal analysis of MAJ publishing patterns. - Findings - The MAJ publishes around 40 articles each year with citations of this work steadily growing over time. The journal has attracted contributors from around the globe, most often affiliated with the USA, the UK and Australia. Thematic evolution of the journal's themes reveals that it has expanded its scope to include topics such as internal auditing, internal control and corporate governance, whilst co-authorship analysis reveals that the journal's collaboration network has grown to span the globe. - Research limitations/implications - As this study uses data from the Scopus database, any shortcomings therein will be reflected in the study. - Originality/value - This study provides the first overview of the MAJ's publication and citation trends as well as the evolution of its thematic structure. It also suggests future directions that the journal might take. -C1 [Kumar, Satish; Pandey, Nitesh; Sureka, Riya] Malaviya Natl Inst Technol, Dept Management Studies, Jaipur, Rajasthan, India. - [Burton, Bruce] Univ Dundee, Sch Business, Dundee, Scotland. -C3 National Institute of Technology (NIT System); Malaviya National - Institute of Technology Jaipur; University of Dundee -RP Kumar, S (corresponding author), Malaviya Natl Inst Technol, Dept Management Studies, Jaipur, Rajasthan, India. -EM skumar.dms@mnit.ac.in; 2018rbm9016@mnit.ac.in; b.m.burton@dundee.ac.uk; - riyasureka@gmail.com -RI Sureka, Riya/AFK-7280-2022; Kumar, Satish/M-8694-2017; Pandey, - Nitesh/ABI-7684-2020 -OI Kumar, Satish/0000-0001-5200-1476; Pandey, Nitesh/0000-0002-3943-8339; - Burton, Bruce/0000-0003-2989-9024; Sureka, Riya/0000-0001-6494-5917; -CR Acedo FJ, 2006, J MANAGE STUD, V43, P957, DOI 10.1111/j.1467-6486.2006.00625.x - Alonso S, 2009, J INFORMETR, V3, P273, DOI 10.1016/j.joi.2009.04.001 - Amran A, 2008, MANAG AUDIT J, V24, P39, DOI 10.1108/02686900910919893 - 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Sarens G, 2006, MANAG AUDIT J, V21, P63, DOI 10.1108/02686900610634766 - Schffer U, 2008, ACCOUNT HIST, V13, P33, DOI 10.1177/1032373207083926 - SCHWERT GW, 1993, J FINANC ECON, V33, P369, DOI 10.1016/0304-405X(93)90012-Z - Shappero Mike., 2003, MANAG AUDIT J, V18, P478, DOI DOI 10.1108/02686900310482623 - Soh DSB, 2011, MANAG AUDIT J, V26, P605, DOI 10.1108/02686901111151332 - Sulaiman M., 2004, Managerial Auditing Journal, V19, P493 - Uysal ÖÖ, 2010, J BUS ETHICS, V93, P137, DOI 10.1007/s10551-009-0187-9 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Vasarhelyi M.A., 1988, Accounting Historians Journal, V15, P45, DOI DOI 10.2308/0148-4184.15.1.45 - Yang D.C., 2004, Managerial Auditing Journal, V19, P544, DOI DOI 10.1108/02686900410530547 -NR 65 -TC 26 -Z9 26 -U1 5 -U2 57 -PU EMERALD GROUP PUBLISHING LTD -PI BINGLEY -PA HOWARD HOUSE, WAGON LANE, BINGLEY BD16 1WA, W YORKSHIRE, ENGLAND -SN 0268-6902 -EI 1758-7735 -J9 MANAG AUDIT J -JI Manag. Audit. J. -PD MAY 12 -PY 2021 -VL 36 -IS 2 -BP 280 -EP 313 -DI 10.1108/MAJ-12-2019-2517 -EA FEB 2021 -PG 34 -WC Business, Finance; Management -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA YY1XM -UT WOS:000621468100001 -OA Green Submitted -DA 2025-07-11 -ER - -PT J -AU Zafar, MB - Abu-Hussin, MF -AF Zafar, Muhammad Bilal - Abu-Hussin, Mohd Fauzi -TI Halal purchasing decisions and consumer behavior: a multi method review -SO JOURNAL OF ISLAMIC MARKETING -LA English -DT Review; Early Access -DE Halal purchasing decisions; Consumer behavior; Bibliometric analysis; - Systematic review; Halal market -ID MUSLIM CONSUMERS; FOOD-PRODUCTS; COSMETIC PRODUCTS; PLANNED BEHAVIOR; - INTENTION; DETERMINANTS; ATTITUDE; CERTIFICATION; RELIGIOSITY; - INFORMATION -AB Purpose - The purpose of this study is to provide a comprehensive exploration of academic research on halal purchasing decisions and consumer behavior by integrating bibliometric and systematic review methodologies. Design/methodology/approach - This study uses a multi-method approach, combining bibliometric and systematic review methodologies, to comprehensively analyze the domain of halal purchasing decisions and consumer behavior. A data set of 184 articles published between 2007 and 2024 was sourced from the Scopus database. The bibliometric analysis was conducted using Bibliometrix in R, facilitating performance analysis, science mapping and network analysis to explore key authors, affiliations, collaborations and thematic trends. Additionally, the systematic review examined the limitations and future research areas discussed in prior studies, providing the basis for formulating potential research questions to address identified gaps. Findings - The study identifies significant contributions within the domain of halal purchasing decisions and consumer behavior, emphasizing the critical roles of religiosity, trust and halal certification as dominant themes. Bibliometric analysis reveals key authors, influential publications and collaborative networks, highlighting Malaysia as a central hub for research in this field. Additionally, the analysis underscores the intellectual structure and thematic evolution, identifying underexplored areas such as non-Muslim perspectives, emerging halal industries and geographic diversity. The systematic review complements these insights by addressing recurring methodological and theoretical limitations, offering targeted recommendations for future research. Originality/value - This research uniquely combines bibliometric and systematic review methodologies to provide a comprehensive review of the halal consumer behavior literature, identifying limitations and gaps in prior studies and proposing actionable areas for future research. -C1 [Zafar, Muhammad Bilal] Univ Teknol Malaysia, Fac Social Sci & Humanities, Johor Baharu, Malaysia. - [Zafar, Muhammad Bilal; Abu-Hussin, Mohd Fauzi] Minhaj Univ Lahore, Sch Islamic Econ Banking & Finance, Lahore, Pakistan. -C3 Universiti Teknologi Malaysia; Minhaj University -RP Zafar, MB (corresponding author), Univ Teknol Malaysia, Fac Social Sci & Humanities, Johor Baharu, Malaysia. -EM bilalezafar@gmail.com; mohdfauziabu@utm.my -RI Zafar, Muhammad Bilal/X-5713-2018; Abu-Husin, Mohd/B-9087-2010 -FU Research Management Center, Universiti Teknologi Malaysia under PDRU - [Q.J130000.21A2.07E49]; MG UTM [Q.J130000.3053.05M03] -FX This research was supported by the Research Management Center, - Universiti Teknologi Malaysia under PDRU grant Q.J130000.21A2.07E49 and - 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The aim of this study was to provide a scientometric analysis of the current literature on embryonic TM in broilers, indicating trends, geographic distribution, influential authors, and multidisciplinary links, aiming to provide a comprehensive overview. A search was carried out in December 2024 on Scopus, PubMed, Scielo, and Web of Science using the keywords ("thermal manipulation" OR "temperature manipulation" OR "temperature control" OR "incubation temperature") AND ("incubation" OR "embryo" OR "fetal development") AND broiler. No date restrictions or filters were applied. Only articles that evaluated the TM of embryonated eggs from broilers were selected. Using a dataset of 195 publications from 1994 to 2024, the data were analyzed with Bibliometrix and VOSviewer tools. A sharp increase in scientific output was observed in the last decade, with 71 % of studies published after 2015. Actual central themes include thermotolerance, heat stress, performance, and hatchability. Emerging themes include gene expression, antioxidant, immune response, and acute heat stress. Nine main research networks were identified, with limited interconnection. The United States, Brazil, and Turkey were identified as the main countries, and Sao Paulo State University, Jordan University of Science and Technology, and Wageningen University are the main research institutions. This study shows how TM during egg incubation has become important in broilers and how it can help them handle heat stress better. Future research should focus on combining TM with genetic, nutritional, and environmental strategies to make the birds more productive and sustainable. -C1 [Zangeronimo, Marcio Gilberto; Alvarenga, Renata Ribeiro] Univ Fed Lavras, Lavras, MG, Brazil. -C3 Universidade Federal de Lavras -RP Zangeronimo, MG (corresponding author), Univ Fed Lavras, Lavras, MG, Brazil. -EM zangeronimo@ufla.br -RI Zangeronimo, Marcio/F-3548-2019 -FU FAPEMIG [APQ-00959-21]; CNPq [303851/2019-8] -FX This work was supported by the Brazilian agencies FAPEMIG (APQ-00959-21) - and CNPq (303851/2019-8) -CR Ajayi F.O., 2024, J. Anim. 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Hence, the increasing global interest in contributing to the biofuel supply chain (BSC), from biomass feedstock to biofuel production, has led to a huge amount of scientific production in recent years. In this vein, techno-economic analysis (TEA) of biofuel production to estimate total costs and revenues is highly important for transitioning towards a bioeconomy. This research aims to provide a comprehensive image of the body of knowledge in TEA evolution within the BSC domain. To this end, a systematic science mapping analysis, supported by a bibliometric analysis, is carried out on 1104 articles from 1986 to 2021. As a result, performance indicators of the scientific production within the target literature are presented to explain how this literature has evolved. Besides, thematic trends and conceptual structures of TEA of biofuel production are discovered. The results show that (i) biofuel production and consumption need promotion through tax measures and price subsidies, (ii) the development of cost-competitive algal biofuels has faced many challenges over recent years, and (iii) TEA of algal biofuels to identify commercial improvements and increase the economic feasibility is still lacking, which calls for more in-depth investigations. Consequently, current challenges and future per-spectives of TEA in the BSC domain are rendered. The provided insights enable researchers and decision-makers involved in BSCs to (i) capture the most influential contributors to the field and (ii) identify major research hotspots and potential directions for further development. -C1 [Ranjbari, Meisam; Pan, Junting] Chinese Acad Agr Sci, Inst Agr Resources & Reg Planning, Beijing 100081, Peoples R China. - [Ranjbari, Meisam] Univ Turin, Dept Econ & Stat Cognetti Martiis, Lungo Dora Siena 100 A, I-10153 Turin, Italy. - [Esfandabadi, Zahra Shams] Politecn Torino, Dept Environm Land & Infrastruct Engn DIATI, Corso Duca Abruzzi 24, I-10129 Turin, Italy. - [Esfandabadi, Zahra Shams] Politecn Torino, Energy Ctr Lab, Via Paolo Borsellino 38-16, I-10138 Turin, Italy. - [Shevchenko, Tetiana] Sumy Natl Agrarian Univ, Sci Dept, UA-40031 Sumy, Ukraine. - [Shevchenko, Tetiana] Univ Paris Saclay, Cent Supelec, Lab Genie Ind, F-91190 Gif Sur Yvette, France. - [Scagnelli, Simone Domenico] Edith Cowan Univ, Sch Business & Law, 270 Joondalup Dr, Joondalup, WA 6027, Australia. - [Scagnelli, Simone Domenico] Univ Turin, Dept Management, Turin, Italy. - [Lam, Su Shiung; Tabatabaei, Meisam] Univ Malaysia Terengganu, Higher Inst Ctr Excellence HICoE, Inst Trop Aquaculture & Fisheries AKUATROP, Kuala Nerus 21030, Terengganu, Malaysia. - [Varjani, Sunita] Gujarat Pollut Control Board, Gandhinagar 382010, Gujarat, India. - [Aghbashlo, Mortaza] Univ Tehran, Coll Agr & Nat Resources, Fac Agr Engn & Technol, Dept Mech Engn Agr Machinery, Karaj, Iran. - [Tabatabaei, Meisam] Biofuel Res Team BRTeam, Terengganu, Malaysia. -C3 Chinese Academy of Agricultural Sciences; Institute of Agricultural - Resources & Regional Planning, CAAS; University of Turin; Polytechnic - University of Turin; Polytechnic University of Turin; Ministry of - Education & Science of Ukraine; Sumy National Agrarian University; - Universite Paris Saclay; Edith Cowan University; University of Turin; - Universiti Malaysia Terengganu; University of Tehran -RP Ranjbari, M; Pan, JT (corresponding author), Chinese Acad Agr Sci, Inst Agr Resources & Reg Planning, Beijing 100081, Peoples R China.; Tabatabaei, M (corresponding author), Univ Malaysia Terengganu, Higher Inst Ctr Excellence HICoE, Inst Trop Aquaculture & Fisheries AKUATROP, Kuala Nerus 21030, Terengganu, Malaysia. -EM meisam.ranjbari@unito.it; panjunting@caas.cn; - meisam.tabatabaei@umt.edu.my -RI Varjani, Sunita/A-1069-2014; Ranjbari, Meisam/AAW-9409-2020; Pan, - Junting/AHA-6355-2022; Shams Esfandabadi, Zahra/AAW-9671-2020; - Shevchenko, Tetiana/E-5697-2019; Tabatabaei, Meisam/E-7235-2013; Lam, Su - Shiung/K-7436-2012; Aghbashlo, Mortaza/L-2752-2017; Scagnelli, - Simone/R-3174-2019 -OI Varjani, Sunita/0000-0001-6966-7768; Shams Esfandabadi, - Zahra/0000-0001-9320-4712; Shevchenko, Tetiana/0000-0002-3213-819X; - Aghbashlo, Mortaza/0000-0001-8534-4686; -FU National Key R&D Program of China [2018YFF3503]; Youth Talent Scholar of - Chinese Academy of Agricultural Sciences, Fundamental Research Funds for - Central Non-profit Scientific Institution [1610132020003]; Agricultural - Science and Technology Innovation Project of Chinese Academy of - Agricultural Sciences, Fund of Government purchase of services from - Ministry of Agriculture and Rural Affairs [13220198]; Fund for talents - from State Administration of Foreign Experts Affairs of P.R. China; - Ministry of Higher Education, Malaysia, under the Higher Institution - Centre of Excellence (HICoE); Institute of Tropical Aquaculture and - Fisheries (AKUATROP) program [56052, UMT/CRIM/2-2/5 Jilid 2 (11)]; - Biofuel Research Team (BRTeam) -FX The authors gratefully acknowledge financial support of National Key R&D - Program of China (No.2018YFF3503), Youth Talent Scholar of Chinese - Academy of Agricultural Sciences, Fundamental Research Funds for Central - Non-profit Scientific Institution (No. 1610132020003), Agricultural - Science and Technology Innovation Project of Chinese Academy of - Agricultural Sciences, Fund of Government purchase of services from - Ministry of Agriculture and Rural Affairs (No. 13220198), Fund for - talents from State Administration of Foreign Experts Affairs of P.R. - China. M.T. would like to acknowledge the support from the Ministry of - Higher Education, Malaysia, under the Higher Institution Centre of - Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries - (AKUATROP) program (Vot. no. 56052, UMT/CRIM/2-2/5 Jilid 2 (11)), and - the support by the Biofuel Research Team (BRTeam). -CR Abbasi M, 2021, J CLEAN PROD, V323, DOI 10.1016/j.jclepro.2021.129100 - Abdurakhman YB, 2018, CHEM ENG RES DES, V134, P564, DOI 10.1016/j.cherd.2018.04.044 - Agbo FJ, 2021, SMART LEARN ENVIRON, V8, DOI 10.1186/s40561-020-00145-4 - Aghbashlo M, 2019, WASTE MANAGE, V87, P485, DOI 10.1016/j.wasman.2019.02.029 - Al-attab K, 2017, BIOFUELS-UK, V8, P17, DOI 10.1080/17597269.2016.1196326 - Alhashimi HA, 2017, RESOUR CONSERV RECY, V118, P13, DOI 10.1016/j.resconrec.2016.11.016 - Ali AAM, 2021, BIOFUELS-UK, V12, P645, DOI 10.1080/17597269.2018.1519758 - Ambaye Teklit Gebregiorgis, 2021, J Environ Manage, V290, P112627, DOI 10.1016/j.jenvman.2021.112627 - Andrade TA, 2019, CHEM ENG RES DES, V141, P1, DOI 10.1016/j.cherd.2018.10.026 - 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Design/methodology/approach - To explore the studies focused on the area under investigation, the authors performed a search in ISI Web of Science and Scopus using the combination of keywords such as Knowledge managementAND Performance.Generally, this study covered a period of 33 years, from 1988 to 2021 because the first study was published in 1970 and the databases have not covered all the journals and studies which date back to the early 1970s or 1980s. The final data set comprised 1,583 publications with 40 articles removed during the screening and eligibility process.Findings - The results of the bibliometric analysis indicate that the interest in the area of knowledge management and performance has significantly increased, especially from 2000 to 2021. The application of bibliometric analysis on the relationship between knowledge management and performance uncovered various themes, productive authors and widely cited documents. The study highlighted how the knowledge management-performance relationship has evolved over the years and how the interplay between knowledge management and performance may help the firms in gaining the sustainable competitive advantage.Originality/value - To the best of the author's knowledge, this study is the first of its kind to conduct the bibliometric analysis on knowledge management and performance. This study can be a starting point for scholars interested in understanding how knowledge management is related to performance. -C1 [Farooq, Rayees] Sohar Univ, Fac Business, Sohar, Oman. -C3 Sohar University -RP Farooq, R (corresponding author), Sohar Univ, Fac Business, Sohar, Oman. -EM rayeesfarooq@rediffmail.com -RI Farooq, Dr Rayees/J-3278-2019 -CR Abeh A, 2021, INT J KNOWL MAN STUD, V12, P352, DOI 10.1504/IJKMS.2021.118346 - Acedo FJ, 2005, INT BUS REV, V14, P619, DOI 10.1016/j.ibusrev.2005.05.003 - Adams G. 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P., 2006, Journal of Knowledge Management, V10, P143, DOI 10.1108/13673270610670911 - Mat SRT, 2021, SCIENTOMETRICS, V126, P2013, DOI 10.1007/s11192-020-03834-6 - Mougenot B, 2022, ENVIRON DEV SUSTAIN, V24, P1031, DOI 10.1007/s10668-021-01481-2 - NARANAN S, 1970, NATURE, V227, P631, DOI 10.1038/227631a0 - NONAKA I, 1994, ORGAN SCI, V5, P14, DOI 10.1287/orsc.5.1.14 - NONAKA I, 1991, HARVARD BUS REV, V69, P96 - Omotehinwa TO, 2022, HELIYON, V8, DOI 10.1016/j.heliyon.2022.e09510 - Paswan AK, 2009, IND MARKET MANAG, V38, P173, DOI 10.1016/j.indmarman.2008.12.005 - Persson O., 2009, Celebrating scholarly communication studies: a festschrift for Olle Persson at his 60th birthday, V5, P9 - PRITCHARD A, 1969, J DOC, V25, P348 - Qamar Y, 2022, PERS REV, V51, P251, DOI 10.1108/PR-04-2020-0247 - Singh KP, 2014, LIBR MANAGE, V35, P134, DOI 10.1108/LM-05-2013-0039 - Singh Sanjay Kumar, 2008, Journal of Knowledge Management, V12, P3, DOI 10.1108/13673270810884219 - Teece DJ, 1997, STRATEGIC MANAGE J, V18, P509, DOI 10.1002/(SICI)1097-0266(199708)18:7<509::AID-SMJ882>3.0.CO;2-Z - Tseng SM, 2008, EXPERT SYST APPL, V34, P734, DOI 10.1016/j.eswa.2006.10.008 - van Eck NJ, 2014, J INFORMETR, V8, P802, DOI 10.1016/j.joi.2014.07.006 - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - Walczak S, 2008, LEARN ORGAN, V15, P486, DOI 10.1108/09696470810907392 - Wallace D.P., 2007, KNOWLEDGE MANAGEMENT - Wang CL, 2008, EUR J INFORM SYST, V17, P219, DOI 10.1057/ejis.2008.12 - Wong KY, 2015, INFORM DEV, V31, P239, DOI 10.1177/0266666913513278 - Yu DJ, 2020, INT J MACH LEARN CYB, V11, P715, DOI 10.1007/s13042-019-01028-y - Zack M, 2009, J KNOWL MANAG, V13, P392, DOI 10.1108/13673270910997088 -NR 87 -TC 59 -Z9 59 -U1 11 -U2 115 -PU EMERALD GROUP PUBLISHING LTD -PI Leeds -PA Floor 5, Northspring 21-23 Wellington Street, Leeds, W YORKSHIRE, - ENGLAND -SN 1367-3270 -EI 1758-7484 -J9 J KNOWL MANAG -JI J. Knowl. Manag. -PD JUL 24 -PY 2023 -VL 27 -IS 7 -BP 1948 -EP 1991 -DI 10.1108/JKM-06-2022-0443 -EA DEC 2022 -PG 44 -WC Information Science & Library Science; Management -WE Social Science Citation Index (SSCI) -SC Information Science & Library Science; Business & Economics -GA M7NT3 -UT WOS:000900954100001 -DA 2025-07-11 -ER - -PT J -AU Nath, S - Thomson, WM - Baker, SR - Jamieson, LM -AF Nath, Sonia - Thomson, William Murray - Baker, Sarah R. - Jamieson, Lisa M. -TI A bibliometric analysis of Community Dentistry and Oral - Epidemiology: Fifty years of publications -SO COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY -LA English -DT Article -DE bibliometric analysis; network maps; oral epidemiology; performance - analysis; scientometrics; community dentistry -ID HEALTH; CARIES; INDEX -AB Objectives: In celebration of the journal's 50th anniversary, the aim of the study was to review the whole collection of Community Dentistry and Oral Epidemiology (CDOE) publications from 1973 to 2022 and provide a complete overview of the main publication characteristics.Methods: The study used bibliometric techniques such as performance and science mapping analysis of 3428 articles extracted from the Scopus database. The data were analysed using the 'Bibliometrix' package in R. The journal's scientific production was examined, along with the yearly citation count, the distribution of publications based on authors, the corresponding author's country and affiliation and citation count, citing source and keywords. Bibliometric network maps were constructed to determine the conceptual, intellectual and social collaborative structure over the past 50 years. The trending research topics and themes were identified.Results: The total number of articles and average citations has increased over the years. D Locker, AJ Spencer, A Sheiham and WM Thomson were the most frequently published authors, and PE Petersen, GD Slade and AI Ismail published papers with the highest citations. The most published countries were the United States, United Kingdom, Brazil and Canada, frequently engaging in collaborative efforts. The most common keywords used were 'dental caries', 'oral epidemiology' and 'oral health'. The trending topics were healthcare and health disparities, social determinants of health, systematic review and health inequalities. Epidemiology, oral health and disparities were highly researched areas.Conclusion: This bibliometric study reviews CDOE's significant contribution to dental public health by identifying key research trends, themes, influential authors and collaborations. The findings provide insights into the need to increase publications from developing countries, improve gender diversity in authorship and broaden the scope of research themes. -C1 [Nath, Sonia; Jamieson, Lisa M.] Univ Adelaide, Australian Res Ctr Populat Oral Hlth, Adelaide, SA, Australia. - [Thomson, William Murray] Univ Otago, Fac Dent, Dunedin, New Zealand. - [Baker, Sarah R.] Univ Sheffield, Sch Clin Dent, Sheffield, England. - [Nath, Sonia] Univ Adelaide, Australian Res Ctr Populat Oral Hlth, Adelaide Dent Sch, Adelaide, SA 5000, Australia. -C3 University of Adelaide; University of Otago; University of Sheffield; - University of Adelaide -RP Nath, S (corresponding author), Univ Adelaide, Australian Res Ctr Populat Oral Hlth, Adelaide Dent Sch, Adelaide, SA 5000, Australia. -EM sonia.nath@adelaide.edu.au -RI Jamieson, Lisa/M-5914-2014; Baker, Sarah/B-3498-2009; Thomson, - William/A-4971-2008; Nath, Sonia/AAE-6630-2022 -OI Baker, Sarah/0000-0002-2861-451X; Thomson, William - Murray/0000-0003-0588-6843 -FU SN is supported by the Australian Government Research Training Program - Scholarship. LMJ is supported by a National Health and Medical Research - Council Senior Research Fellowship. Open access publishing facilitated - by The University of Adelaide, as part of; Australian Government - Research Training Program Scholarship; National Health and Medical - Research Council Senior Research Fellowship; University of Adelaide, as - part of the Wiley - The University of Adelaide agreement via the Council - of Australian University Librarians -FX SN is supported by the Australian Government Research Training Program - Scholarship. LMJ is supported by a National Health and Medical Research - Council Senior Research Fellowship. Open access publishing facilitated - by The University of Adelaide, as part of the Wiley - The University of - Adelaide agreement via the Council of Australian University Librarians. -CR Ahmad P, 2020, PERIODONTOL 2000, V82, P286, DOI 10.1111/prd.12328 - Ali MJ, 2021, SEMIN OPHTHALMOL, V36, P139, DOI 10.1080/08820538.2021.1922975 - Aoun SG, 2013, WORLD NEUROSURG, V80, pE85, DOI 10.1016/j.wneu.2012.01.052 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Boyack KW, 2010, J AM SOC INF SCI TEC, V61, P2389, DOI 10.1002/asi.21419 - Celeste RK, 2016, COMMUNITY DENT ORAL, V44, P557, DOI 10.1111/cdoe.12249 - CROSSNER CG, 1981, COMMUNITY DENT ORAL, V9, P182, DOI 10.1111/j.1600-0528.1981.tb01052.x - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Ejaz H, 2022, INT J ENV RES PUB HE, V19, DOI 10.3390/ijerph191912407 - Fortuna G, 2020, J ORAL PATHOL MED, V49, P555, DOI 10.1111/jop.13076 - Haag DG, 2023, COMMUNITY DENT ORAL, V51, P1045, DOI 10.1111/cdoe.12831 - Hansen D.L., 2020, ANAL SOCIAL MEDIA NE, P79, DOI [10.1016/B978-012-817756-3.00006-6, 10.1016/B978-0-12-817756-3.00006-6, DOI 10.1016/B978-0-12-817756-3.00006-6] - HELOE LA, 1981, COMMUNITY DENT ORAL, V9, P294, DOI 10.1111/j.1600-0528.1981.tb00350.x - Huang C, 2020, EDUC REV, V72, P281, DOI 10.1080/00131911.2019.1566212 - Ismail AI, 2007, COMMUNITY DENT ORAL, V35, P170, DOI 10.1111/j.1600-0528.2007.00347.x - Khan AS, 2021, INT ENDOD J, V54, P1819, DOI 10.1111/iej.13595 - Kirk A., 2021, SANKEY DIAGRAM - KOCH GG, 1977, BIOMETRICS, V33, P133, DOI 10.2307/2529309 - Liu FH, 2022, J DENT SCI, V17, P642, DOI 10.1016/j.jds.2021.08.002 - Lotka AlfredJames., 1926, Journal of Washington Academy Sciences, DOI DOI 10.1016/S0016-0032(26)91166-6 - Mayta-Tovalino F, 2023, INT DENT J, V73, P157, DOI 10.1016/j.identj.2022.05.003 - Moraes Rafael Ratto de, 2020, Braz. 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Oral Epidemiol. -PD APR -PY 2024 -VL 52 -IS 2 -BP 171 -EP 180 -DI 10.1111/cdoe.12910 -EA OCT 2023 -PG 10 -WC Dentistry, Oral Surgery & Medicine; Public, Environmental & Occupational - Health -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Dentistry, Oral Surgery & Medicine; Public, Environmental & Occupational - Health -GA KM1H7 -UT WOS:001078591500001 -PM 37798876 -OA Green Published, Green Accepted, hybrid -DA 2025-07-11 -ER - -PT J -AU Ventaja-Cruz, J - Rincón, JMC - Tejada-Medina, V - Martín-Moya, R -AF Ventaja-Cruz, Javier - Rincon, Jesus M. Cuevas - Tejada-Medina, Virginia - Martin-Moya, Ricardo -TI A Bibliometric Study on the Evolution of Women's Football and - Determinants Behind Its Growth over the Last 30 Years -SO SPORTS -LA English -DT Review -DE female soccer; women's sports; motivation; scientific production; - Biblioshiny; science mapping -ID FEMALE SOCCER PLAYERS; CRUCIATE LIGAMENT INJURIES; TRAINING-PROGRAM; - SPORTS INJURY; YOUTH SOCCER; KNEE INJURY; PERFORMANCE; REHABILITATION; - PERCEPTIONS; BASKETBALL -AB Background: The evolution of women's football over the past three decades has been remarkable in terms of development, visibility, and acceptance, transforming into a discipline with growing popularity and professionalization. Significant advancements in gender equality and global visibility have occurred, and the combination of emerging talent, increasing commercial interest, and institutional support will continue to drive the growth and consolidation of women's football worldwide. Methods: The purpose of this study was to present a bibliometric analysis of articles on the evolution of women's football in terms of scientific production as well as its causes and motivations over the past 30 years (1992-2024). A total of 128 documents indexed in the Web of Science database were reviewed. Outcome measures were analyzed using RStudio version 4.3.1 (Viena, Austria) software and the Bibliometrix data package to evaluate productivity indicators including the number of articles published per year, most productive authors, institutions, countries, and journals as well as identify the most cited articles and common topics. Results: Scientific production on women's football has shown sustained growth, particularly since 2010. Key research areas have focused on injury prevention, physical performance, psychosocial factors, motivation, and leadership. The United States, the United Kingdom, and Spain have emerged as the most productive countries in this field, with strong international collaboration reflected in co-authorship networks. Conclusions: The study revealed a clear correlation between the evolution of women's football and the increase in scientific production, providing a strong foundation for future research on emerging topics such as the importance of psychological factors, sport motivation and emotional well-being on performance, gender differences at the physiological and biomechanical levels, or misogyny in social networks, thus promoting comprehensive development in this sport modality. -C1 [Ventaja-Cruz, Javier; Tejada-Medina, Virginia; Martin-Moya, Ricardo] Univ Granada, Fac Educ & Sport Sci, Dept Phys Educ & Sports, Melilla Campus, ES-52071 Melilla, Spain. - [Ventaja-Cruz, Javier] Melilla Football Federat, ES-52001 Melilla, Spain. - [Rincon, Jesus M. 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The study focused on the research trends, scholar's productivity, and thematic focus of scientific publications in the field of smart learning environments. A total of 1081 data consisting of peer-reviewed articles were retrieved from the Scopus database. A bibliometric approach was applied to analyse the data for a comprehensive overview of the trend, thematic focus, and scientific production in the field of smart learning environments. The result from this bibliometric analysis indicates that the first paper on smart learning environments was published in 2002; implying the beginning of the field. Among other sources, "Computers & Education," "Smart Learning Environments," and "Computers in Human Behaviour" are the most relevant outlets publishing articles associated with smart learning environments. The work of Kinshuk et al., published in 2016, stands out as the most cited work among the analysed documents. The United States has the highest number of scientific productions and remained the most relevant country in the smart learning environment field. Besides, the results also showed names of prolific scholars and most relevant institutions in the field. Keywords such as "learning analytics," "adaptive learning," "personalized learning," "blockchain," and "deep learning" remain the trending keywords. Furthermore, thematic analysis shows that "digital storytelling" and its associated components such as "virtual reality," "critical thinking," and "serious games" are the emerging themes of the smart learning environments but need to be further developed to establish more ties with "smart learning". The study provides useful contribution to the field by clearly presenting a comprehensive overview and research hotspots, thematic focus, and future direction of the field. These findings can guide scholars, especially the young ones in field of smart learning environments in defining their research focus and what aspect of smart leaning can be explored. -C1 [Agbo, Friday Joseph; Suhonen, Jarkko; Tukiainen, Markku] Univ Eastern Finland, Sch Comp, POB 111, FIN-80101 Joensuu, Finland. - [Oyelere, Solomon Sunday] Lulea Univ Technol, Dept Comp Sci Elect & Space Engn, Lulea, Sweden. -C3 University of Eastern Finland; Lulea University of Technology -RP Agbo, FJ (corresponding author), Univ Eastern Finland, Sch Comp, POB 111, FIN-80101 Joensuu, Finland. -EM fridaya@uef.fi -RI Oyelere, Solomon Sunday/AAE-7541-2020 -OI Friday Joseph, Agbo/0000-0002-9171-7175; Oyelere, Solomon - Sunday/0000-0001-9895-6796; Suhonen, Jarkko/0000-0002-3501-6286 -CR Cárdenas-Robledo LA, 2018, TELEMAT INFORM, V35, P1097, DOI 10.1016/j.tele.2018.01.009 - Agbo FJ, 2019, INT J LEARN TECHNOL, V14, P331 - [Anonymous], 2009, International Journal of Interactive Mobile Technologies, DOI DOI 10.3991/IJIM.V3I1.680 - Aria M., 2020, BIBLIOSHINY BLIBLIOM - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Arici F, 2019, COMPUT EDUC, V142, DOI 10.1016/j.compedu.2019.103647 - Atchison CJ, 2020, PERCEPTIONS BEHAV RE - Baker RSJD, 2010, INT J HUM-COMPUT ST, V68, P223, DOI 10.1016/j.ijhcs.2009.12.003 - Burghardt C, 2008, INT CONF PERVAS COMP, P377, DOI 10.1109/PERCOM.2008.96 - D'mello S., 2013, ACM Transactions on Interactive Intelligent Systems, V2, P1 - Esfahani H., 2019, International Journal of Data and Network Science, V3, P145, DOI [DOI 10.5267/J.IJDNS.2019.2.007, 10.5267/j.ijdns.2019.2.007] - Labib AE, 2017, COMPUT HUM BEHAV, V73, P433, DOI 10.1016/j.chb.2017.03.054 - Gilani E., 2019, International Journal of Data and Network Science, V3, P201, DOI DOI 10.5267/J.IJDNS.2019.2.004 - Grant J, 2000, BMJ-BRIT MED J, V320, P1107, DOI 10.1136/bmj.320.7242.1107 - Hammad R, 2016, INT CONF UTIL CLOUD, P185, DOI 10.1145/2996890.3007859 - Harris C., 2020, SOC INF TECHN TEACH, P1117 - Heinemann C., 2018, Smart Universities. 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Smart Innovation, Systems and Technologies, V1st - Uskov VL, 2016, SMART INNOV SYST TEC, V59, P3, DOI 10.1007/978-3-319-39690-3_1 - Waheed H, 2018, BEHAV INFORM TECHNOL, V37, P941, DOI 10.1080/0144929X.2018.1467967 - Wang H., 2020, IOP C SERIES MAT SCI, V806, DOI [10.1088/1757-899X/806/1/012055, DOI 10.1088/1757-899X/806/1/012055] - Zacharia ZC, 2015, ETR&D-EDUC TECH RES, V63, P257, DOI 10.1007/s11423-015-9370-0 - Zervas P, 2015, TECHNOL KNOWL LEARN, V20, P185, DOI 10.1007/s10758-015-9256-6 - Zupic I, 2015, ORGAN RES METHODS, V18, P429, DOI 10.1177/1094428114562629 -NR 48 -TC 147 -Z9 150 -U1 12 -U2 91 -PU SPRINGER HEIDELBERG -PI HEIDELBERG -PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY -EI 2196-7091 -J9 SMART LEARN ENVIRON -JI Smart Learn. Env. -PD JAN 15 -PY 2021 -VL 8 -IS 1 -AR 1 -DI 10.1186/s40561-020-00145-4 -PG 25 -WC Education & Educational Research -WE Emerging Sources Citation Index (ESCI) -SC Education & Educational Research -GA SZ7YU -UT WOS:000666776500001 -PM 40477293 -OA Green Published, gold -DA 2025-07-11 -ER - -PT J -AU Utegenova, AB - Yermagambetova, AP - Kabdrakhmanova, GB - Khamidulla, AA - Urasheva, ZU - Kenzhina, NK - Zhussupova, Z - Nurlanova, GN -AF Utegenova, Aigerim B. - Yermagambetova, Aigul P. - Kabdrakhmanova, Gulnar B. - Khamidulla, Alima A. - Urasheva, Zhanylsyn U. - Kenzhina, Nazym K. - Zhussupova, Zhanna - Nurlanova, Gulzhanat N. -TI Bibliometric Analysis of Alpha-Synuclein Determination by Biopsy in - Peripheral Tissues of Patients With Parkinson's Disease -SO INTERNATIONAL JOURNAL OF TELEMEDICINE AND APPLICATIONS -LA English -DT Review -DE alpha-synuclein; bibliometric analysis; biopsy; Parkinson's disease -ID BIOMARKER; SKIN -AB Study Evaluation: The bibliometric analysis of the published results of the alpha-synuclein (alpha-syn) detection study in the peripheral tissues of patients with Parkinson's disease was carried out by us to study scientific activity and scientific productivity, to measure the quantitative and qualitative characteristics of scientific publications, author productivity, and citation of works, as well as the degree of interrelation between authors, journals, institutes, and countries.Purpose: This study is aimed at bibliometrically analyzing the results of studies on the detection of alpha-syn in peripheral tissue biopsy of patients with Parkinson's disease from 2013 to 2023.Methods: The data was extracted from the Scopus database collection using an inclusive search strategy. Performance analysis and science mapping were conducted using RStudio v.4.3.1 with the bibliometrix R-package. The analyzed data encompassed trends in publication and citation and the identification of leading institutions, primary sources, authors, and collaborative countries.Results: A total of 124 relevant studies from 53 different sources were thoroughly analyzed. The analysis included the materials of 843 authors, which together gave an impressive average of 37.67 citations per document over the past decade. The annual growth rate in this area of research, according to calculations, was 10.84%, indicating a steady increase in the number of publications over the study period. The huge volume of research results is highlighted by the inclusion of 231 unique keywords of authors.Conclusion: Studies on the detection of pathological alpha-syn in peripheral tissues for early morphological verification of the diagnosis of Parkinson's disease are relevant in clinical neurology. alpha-syn detected in the skin biopsy of patients on the basis of this study and data from the world literature meets the requirements for biomarkers. -C1 [Utegenova, Aigerim B.; Yermagambetova, Aigul P.; Kabdrakhmanova, Gulnar B.; Khamidulla, Alima A.; Urasheva, Zhanylsyn U.] West Kazakhstan Marat Ospanov State Med Univ, Dept Neurol, Aktobe, Kazakhstan. - [Kenzhina, Nazym K.] West Kazakhstan High Med Coll, Course Therapy, Uralsk, Kazakhstan. - [Zhussupova, Zhanna] West Kazakhstan Marat Ospanov State Med Univ, Dept Neurol & Psychiat, Aktobe, Kazakhstan. - [Nurlanova, Gulzhanat N.] West Kazakhstan Marat Ospanov State Med Univ, Dept Infect Dis, Aktobe, Kazakhstan. -C3 West Kazakhstan Marat Ospanov Medical University; West Kazakhstan Marat - Ospanov Medical University; West Kazakhstan Marat Ospanov Medical - University -RP Utegenova, AB (corresponding author), West Kazakhstan Marat Ospanov State Med Univ, Dept Neurol, Aktobe, Kazakhstan. -EM 87012226598@mail.ru -RI Khamidulla, Alima/ABF-2605-2021 -CR Ablakimova N., 2023, Antibiotics, V12 - Alves F. 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Appl. -PY 2025 -VL 2025 -IS 1 -AR 6469893 -DI 10.1155/ijta/6469893 -PG 10 -WC Health Care Sciences & Services -WE Emerging Sources Citation Index (ESCI) -SC Health Care Sciences & Services -GA W6T8L -UT WOS:001419882300001 -PM 39989622 -OA gold -DA 2025-07-11 -ER - -PT J -AU Hernández-Torrano, D - Bessems, K - Buijs, G - Lassalle, C - Datema, W - Jourdan, D -AF Hernandez-Torrano, Daniel - Bessems, Kathelijne - Buijs, Goof - Lassalle, Camille - Datema, William - Jourdan, Didier -TI Health promotion in the school context: a scientific mapping of the - literature -SO HEALTH EDUCATION -LA English -DT Article -DE School health promotion; Well-being; Health education; Ottawa charter; - Bibliometric review; Science mapping; VOSviewer; Bibliometrix -ID WEB-OF-SCIENCE; EVERY SCHOOL; PATTERNS; COVERAGE; SCOPUS -AB Purpose - This study presents an overview of research literature on health promotion in schools, utilizing metadata extracted from 4,328 publications indexed in the Scopus database over the past 35 years. Design/methodology/approach - A bibliometric approach was used to analyze the development and current state of using publication and citation data. A structured keyword search was conducted in the Scopus database to retrieve relevant publications in the field. Frequency counts, rank-ordered tables and time series charts were used to illustrate the dynamic growth of publication and citation data, the core journals, the leading countries and the most frequently used keywords in research on health promotion in school contexts. A series of social network analyses was conducted to explore and visualize the social, intellectual and conceptual structure of the field. Findings - Findings demonstrate that health promotion in the school context is a growing research field that has gained significant momentum in recent years. The research in this field is widely distributed internationally, but the research output is dominated by the US and other English-speaking countries. The study reveals a trend toward increased collaboration among research groups. The level of international collaboration varies. The research field is highly interdisciplinary, and the main research themes addressed in the literature include mental health, well-being and quality of life; health behaviors; oral health education; sexual and reproductive education and general health promotion and health education in schools. Originality/value - This is the first study to map the development of a research field with growing recognition. It provides a comprehensive overview of the emerging field of health promotion in the school context and its progress over time, contributing to the organization of the research domain. The study demonstrates the need for a new framework for health promotion research that supports the sustainability of health promotion research in schools. -C1 [Hernandez-Torrano, Daniel] Nazarbayev Univ, Grad Sch Educ, Astana, Kazakhstan. - [Bessems, Kathelijne] Maastricht Univ, NUTRIM Inst Nutr & Translat Res Metab, Maastricht, Netherlands. - [Buijs, Goof; Jourdan, Didier] UNESCO Chair, Montpellier, France. - [Buijs, Goof; Jourdan, Didier] WHO Collaborating Ctr Global Hlth & Educ, Montpellier, France. - [Lassalle, Camille] Maastricht Univ, Maastricht, Netherlands. - [Datema, William] Soc Publ Hlth Educ, Washington, DC USA. - [Jourdan, Didier] Univ Clermont Auvergne, Clermont Auvergne, France. -C3 Nazarbayev University; Maastricht University; Maastricht University; - Universite Clermont Auvergne (UCA) -RP Hernández-Torrano, D (corresponding author), Nazarbayev Univ, Grad Sch Educ, Astana, Kazakhstan. -EM daniel.torrano@nu.edu.kz; k.bessems@maastrichtuniversity.nl; - goof.buijs@unescochair-ghe.org; lassalleccm@gmail.com; - pottsdatema@gmail.com; didier.jourdan@uca.fr -RI ; Hernández-Torrano, Daniel/AAC-8871-2021 -OI bessems, kathelijne/0000-0003-3879-9279; Jourdan, - Didier/0000-0001-9303-0847; Hernandez-Torrano, - Daniel/0000-0001-9137-2392 -FU UNESCO Chair; WHO Collaborating Center for Global Health and Education -FX We would like to acknowledge and thank the UNESCO Chair and WHO - Collaborating Center for Global Health and Education. Through their - support, the authors of this study were able to unite diverse - perspectives, fostering an environment of shared knowledge that has - greatly contributed to the depth and scope of our research. -CR Aboelela SW, 2007, HEALTH SERV RES, V42, P329, DOI 10.1111/j.1475-6773.2006.00621.x - ALLENSWORTH DD, 1987, J SCHOOL HEALTH, V57, P409, DOI 10.1111/j.1746-1561.1987.tb03183.x - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Bonell C, 2013, HEALTH PLACE, V21, P180, DOI 10.1016/j.healthplace.2012.12.001 - Coccia M, 2016, P NATL ACAD SCI USA, V113, P2057, DOI 10.1073/pnas.1510820113 - Craigie AM, 2011, MATURITAS, V70, P266, DOI 10.1016/j.maturitas.2011.08.005 - Ding Y, 2000, SCIENTOMETRICS, V47, P55, DOI 10.1023/A:1005665709109 - Dooris M., 2007, Global Perspectives on Health Promotion Effectiveness, P327 - Falagas ME, 2008, FASEB J, V22, P338, DOI 10.1096/fj.07-9492LSF - Hernández-Torrano D, 2020, CHILD INDIC RES, V13, P863, DOI 10.1007/s12187-019-09659-x - Ho YCL, 2022, HEALTH PROMOT INT, V37, DOI 10.1093/heapro/daac119 - Hollar Danielle, 2010, J Health Care Poor Underserved, V21, P93, DOI 10.1353/hpu.0.0304 - Hovdenak IM, 2019, INT J BEHAV NUTR PHY, V16, DOI 10.1186/s12966-019-0783-8 - Jones J.T., 1998, WHOS GLOBAL SCH HLTH - Jourdan D., 2023, DOING HLTH PROMOTION, V3 - Jourdan D, 2021, LANCET CHILD ADOLESC, V5, P295, DOI 10.1016/S2352-4642(20)30316-3 - Kivits J, 2019, J EPIDEMIOL COMMUN H, V73, P1061, DOI 10.1136/jech-2019-212511 - Leger LS., 2022, Handbook of Settings-Based Health Promotion, P105 - Mohammadi NK, 2019, HEALTH PROMOT INT, V34, P635, DOI 10.1093/heapro/daz084 - Mongeon P, 2016, SCIENTOMETRICS, V106, P213, DOI 10.1007/s11192-015-1765-5 - Newman MEJ, 2004, P NATL ACAD SCI USA, V101, P5200, DOI 10.1073/pnas.0307545100 - Niu L, 2019, J ADOLESCENT HEALTH, V64, P405, DOI 10.1016/j.jadohealth.2018.09.024 - Norris M, 2007, J INFORMETR, V1, P161, DOI 10.1016/j.joi.2006.12.001 - Nutbeam D., 1992, Health Promot Int, V7, P151, DOI [10.1093/heapro/7.3.151, DOI 10.1093/heapro/7.3.151] - Nutbeam D, 2019, HEALTH EDUC J, V78, P705, DOI 10.1177/0017896918770215 - Potvin L., 2008, Health promotion evaluation practices in the Americas: Values and research, V1 - Potvin L., 2022, MAPPING HLTH PROMOTI, V1 - Roemer R.C., 2015, MEANINGFUL METRICS 2 - Rowling L, 2006, HEALTH EDUC RES, V21, P705, DOI 10.1093/her/cyl089 - Sawyer SM, 2021, LANCET CHILD ADOLESC, V5, P539, DOI 10.1016/S2352-4642(21)00190-5 - Singh VK, 2021, SCIENTOMETRICS, V126, P5113, DOI 10.1007/s11192-021-03948-5 - Turunen H, 2017, HEALTH PROMOT INT, V32, P177, DOI 10.1093/heapro/dax001 - UNESCO Chair on Global Health & Education, 2022, US - van Eck NJ, 2010, SCIENTOMETRICS, V84, P523, DOI 10.1007/s11192-009-0146-3 - VANRIJSBERGEN CJ, 1977, J DOC, V33, P106, DOI 10.1108/eb026637 - Vera-Baceta MA, 2019, SCIENTOMETRICS, V121, P1803, DOI 10.1007/s11192-019-03264-z - WHO, 2014, GLOBAL STATUS REPORT ON VIOLENCE PREVENTION 2014, P1 - World Health Organization, 2021, Health Promotion Glossary of Terms 2021 - World Health Organization (WHO), 2016, WORKING TOGETHER BET - World Health Organization (WHO), 1995, HLTH PROMOTION OTTAW - Young I., 2013, SCH HLTH PROMOTION E, V16, P1 - Young Ian, 2005, Promot Educ, V12, P112, DOI 10.1177/10253823050120030103 -NR 42 -TC 1 -Z9 1 -U1 2 -U2 2 -PU EMERALD GROUP PUBLISHING LTD -PI Leeds -PA Floor 5, Northspring 21-23 Wellington Street, Leeds, W YORKSHIRE, - ENGLAND -SN 0965-4283 -EI 1758-714X -J9 HEALTH EDUC -JI Health Educ. -PD JAN 23 -PY 2025 -VL 125 -IS 1 -BP 68 -EP 84 -DI 10.1108/HE-09-2023-0099 -EA OCT 2024 -PG 17 -WC Public, Environmental & Occupational Health -WE Emerging Sources Citation Index (ESCI) -SC Public, Environmental & Occupational Health -GA S9T0Y -UT WOS:001346376700001 -DA 2025-07-11 -ER - -PT J -AU Khasawneh, N - Al Rousan, R - Sujood -AF Khasawneh, Nermin - Al Rousan, Ramzi - Sujood -TI Mapping global research on space tourism (1993-2022): a three-decade - bibliometric assessment using R and VOSviewer -SO GLOBAL KNOWLEDGE MEMORY AND COMMUNICATION -LA English -DT Article; Early Access -DE Space tourism; Bibliometrics; Performance analysis; Science mapping -ID EXPLORATION; SCIENCE; FUTURE -AB PurposeSpace tourism is currently experiencing significant attention because of its rapid and burgeoning development in the present era. This surge has resulted in an unprecedented growth in publications dedicated to unravelling the intricacies of space tourism. However, there is a conspicuous absence of a large-scale bibliometric analysis focusing on space tourism research from 1993 to 2022. Therefore, the aim of this study is to fill this research gap by examining and mapping the scholarly output published across the world in the spectrum of space tourism over the past 30 years (1993-2022).Design/methodology/approachA corpus of 7,438 publications pertaining to space tourism published from 1993 to 2022 was gathered from the Web of Science Core Collection. Accordingly, bibliometrix package in R and VOSviewer software were used to conduct a comprehensive bibliometric analysis.FindingsThe current study highlights a significant surge in publications related to space tourism, indicating a heightened scholarly interest and a significant paradigm shift in its exploration. Scott M. Smith, affiliated with National Aeronautics Space Administration Johnson Space Center, emerges as the most prolific author. Leading journals in disseminating space tourism research are Acta Astronautica and Aviation Space and Environmental Medicine. Keyword analysis revealed hotspots such as "space flight", "simulated microgravity", "weightlessness" and "stress", while research gaps include "skylab", "shuttle", "cartilage", "herpes virus" and "herniation", offering potential avenues for exploration.Research limitations/implicationsThis study's implications empower stakeholders with actionable insights and deepen the understanding of the evolving landscape of space tourism research, fostering an environment conducive to continuous exploration and innovation in this burgeoning field.Originality/valueThis study enriches the understanding of global space tourism research and offers valuable insights applicable to a diverse audience, including researchers, policymakers and industry stakeholders. The broad applicability of the study's findings underscores its significance, serving as a guide for strategic decision-making and shaping research agendas in the dynamic realm of space tourism. -C1 [Khasawneh, Nermin; Al Rousan, Ramzi] Hashemite Univ, Queen Rania Fac Tourism & Heritage, Dept Sustainable Tourism, Zarqa, Jordan. - [Sujood] Jamia Millia Islamia, Dept Tourism & Hospitality Management, New Delhi, India. -C3 Hashemite University; Jamia Millia Islamia -RP Sujood (corresponding author), Jamia Millia Islamia, Dept Tourism & Hospitality Management, New Delhi, India. -EM sjdkhancool@gmail.com -RI , Dr. Sujood/AAY-9219-2021; Al Rousan, Ramzi/HHZ-1058-2022 -OI , Dr. SUJOOD/0000-0001-9475-2585; -CR Anubha L., 2023, Journal of Foodservice Business Research, P1 - Atkinson LZ, 2018, BJPsych Adv, V24, P74, DOI DOI 10.1192/BJA.2017.3 - Birkle C, 2020, QUANT SCI STUD, V1, P363, DOI 10.1162/qss_a_00018 - Chaudhuri S., 2018, GIS Applications in the Tourism and Hospitality Industry - Correa L.M.C., 2021, RISTI Revista Iberica de Sistemas e Tecnologias de Informacao, P651 - 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Su Y, 2022, SUSTAINABILITY-BASEL, V14, DOI 10.3390/su142214854 - Sustacha Melijosa I.M., 2022, Investigaciones Tursticas - Tarifa-Fernández J, 2023, TOUR HOSP RES, V23, P517, DOI 10.1177/14673584221110358 - Technavio, 2023, Space tourism market size to grow by USD 6,959.36 million from 2023 to 2027: a descriptive analysis of customer landscape, vendor assessment, and market dynamics - Thommandru Abhishek, 2023, Materials Today: Proceedings, P2901, DOI 10.1016/j.matpr.2021.07.059 - Vanegas J.C.P., 2020, RISTI Revista Iberica de Sistemas e Tecnologias de Informacao, P387 - Wang G, 2023, J HOSP TOUR INSIGHTS, V6, P509, DOI 10.1108/JHTI-09-2021-0260 - Wooten JO, 2018, DECISION SCI, V49, P999, DOI 10.1111/deci.12312 - Zhang SBW, 2023, HERIT SCI, V11, DOI 10.1186/s40494-023-00981-w - Zhang YQ, 2023, J ASIAN ARCHIT BUILD, V22, P3128, DOI 10.1080/13467581.2023.2215846 -NR 56 -TC 2 -Z9 2 -U1 4 -U2 8 -PU EMERALD GROUP PUBLISHING LTD -PI Leeds -PA Floor 5, Northspring 21-23 Wellington Street, Leeds, W YORKSHIRE, - ENGLAND -SN 2514-9342 -EI 2514-9350 -J9 GLOB KNOWL MEM COMMU -JI Glob. Knowl. Mem. Commun. -PD 2024 JUL 3 -PY 2024 -DI 10.1108/GKMC-01-2024-0027 -EA JUL 2024 -PG 22 -WC Information Science & Library Science -WE Emerging Sources Citation Index (ESCI) -SC Information Science & Library Science -GA WZ1N5 -UT WOS:001258605400001 -DA 2025-07-11 -ER - -PT J -AU Li, J - Cossette-Roberge, H - Toffa, DH - Deacon, C - Keezer, MR -AF Li, Jimmy - Cossette-Roberge, Helene - Toffa, Denahin Hinnoutondji - Deacon, Charles - Keezer, Mark Robert -TI Sudden unexpected death in epilepsy (SUDEP): A bibliometric analysis -SO EPILEPSY RESEARCH -LA English -DT Article -DE SUDEP; Epilepsy; Bibliometric; Review; Sudden death -ID RISK-FACTORS; ANTIEPILEPTIC DRUGS; UNEXPLAINED DEATH; SEIZURES; - MECHANISMS; METAANALYSIS; SCIENCE; SERIES; APNEA -AB Objective: The literature on sudden unexpected death in epilepsy (SUDEP) has been evolving at a staggering rate. We conducted a bibliometric analysis of the SUDEP literature with the aim of presenting its structure, perfor-mance, and trends.Methods: The Scopus database was searched in April 2023 for documents explicitly detailing SUDEP in their title, abstract, or keywords. After the removal of duplicate documents, bibliometric analysis was performed using the R package bibliometrix and the program VOSviewer. Performance metrics were computed to describe the liter-ature's annual productivity, most relevant authors and countries, and most important publications. Science mapping was performed to visualize the relationships between research constituents by constructing a country collaboration network, co-authorship network, keyword co-occurrence network, and document co-citation network.Results: A total of 2140 documents were analyzed. These documents were published from 1989 onward, with an average number of citations per document of 25.78. Annual productivity had been on the rise since 2006. Out of 6502 authors, five authors were in both the list of the ten most productive and the list of the ten most cited authors: Devinsky O, Sander JW, Tomson T, Ryvlin P, and Lhatoo SD. The USA and the United Kingdom were the most productive and cited countries. Collaborations between American authors and European authors were particularly rich. Prominent themes in the literature included those related to pathophysiology (e.g., cardiac arrhythmia, apnea, autonomic dysfunction), epilepsy characteristics (e.g., epilepsy type, refractoriness, antisei-zure medications), and epidemiology (e.g., incidence, age, sex). Emerging themes included sleep, genetics, ep-ilepsy refractoriness, and non-human studies.Significance: The body of literature on SUDEP is rich, fast-growing, and benefiting from frequent international collaborations. 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M. Fatah -TI Anthropomorphism and consumer behaviour: A SPAR-4-SLR protocol compliant - hybrid review -SO INTERNATIONAL JOURNAL OF CONSUMER STUDIES -LA English -DT Review -DE anthropomorphism; Bibliometrix-R; consumer behaviour; science mapping; - TCCM framework; VOSviewer -ID BRAND ANTHROPOMORPHISM; INDIVIDUAL-DIFFERENCES; BIBLIOMETRIC ANALYSIS; - ACADEMIC RESEARCH; CITATION ANALYSIS; SOCIAL COGNITION; PERCEPTIONS; - TRUST; CUSTOMERS; TOURISM -AB The notion of 'anthropomorphism' has been a subject of intrigue for transdisciplinary academics and scholars for the longest time, as the origin of this concept dates back to the BCE (Before Common Era). Over the past few decades, anthropomorphism literature has been burgeoning in the marketing discipline and its subfields (branding, advertising, consumer behaviour, etc.). This relatively novel stream adopts anthropomorphism as a concept and offers fascinating insights into consumers and their choices, behaviour, and intentions. Although there have been several qualitative review-based assessments of anthropomorphism within the marketing field, none have been informed by quantitative tools or through a framework-based approach. Our hybrid variant of systematic review fills this gap by using bibliometric techniques (performance analysis, co-authorship analysis of countries and authors, and co-word analysis of keywords) and Theories-Context-Characteristics-Methods (TCCM) framework to show the evolution, trends, and intellectual structure of anthropomorphism in consumer behaviour research. We depict the evolving trajectory and trends over time using a sample of 432 peer-reviewed journal articles and 27,671 secondary references (between 2005 and 2023) on anthropomorphism in consumer behaviour. Significant results include identifying and describing the most influential authors, articles, journals and countries, different research streams, their development, and future research directions. We also present six knowledge clusters delineating the intellectual knowledge structure of the field. An additional section depicting theories employed, characteristics explored, contexts examined, and methods utilized in the domain have also been presented. Furthermore, we used the TCCM framework to orchestrate possible trajectories for future research. By doing this, we offer academics and practitioners a systematic comprehension of the advancements in the domain and a comprehensive road map for future research. -C1 [Khan, Fateh Mohd] Aligarh Muslim Univ, Dept Business Adm, Aligarh, India. - [Anas, Mohammad; Uddin, S. M. Fatah] Birla Inst Management Technol, Dept Mkt, Greater Noida, India. - [Uddin, S. M. Fatah] Birla Inst Management Technol, Noida 201306, India. -C3 Aligarh Muslim University -RP Uddin, SMF (corresponding author), Birla Inst Management Technol, Noida 201306, India. -EM smfateh87@gmail.com -RI ; Anas, Mohammad/ADK-2768-2022; Uddin, S M Fatah/AAO-7345-2021; Khan, - Fateh Mohd/HOC-6667-2023 -OI Khan, Fateh Mohd/0000-0002-6400-4348; Uddin, S M - Fatah/0000-0002-3088-7963; Anas, Mohammad/0000-0001-6524-3087; -FU The authors would like to thank the Editor-in-Chief and the anonymous - reviewers for their constructive comments. Their feedback has - significantly improved the quality of this paper. -FX The authors would like to thank the Editor-in-Chief and the anonymous - reviewers for their constructive comments. 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J. Consum. Stud. -PD JAN -PY 2024 -VL 48 -IS 1 -DI 10.1111/ijcs.12985 -EA SEP 2023 -PG 37 -WC Business -WE Social Science Citation Index (SSCI) -SC Business & Economics -GA MJ0U8 -UT WOS:001072517700001 -DA 2025-07-11 -ER - -PT J -AU Elomari, Y - Norouzi, M - Marín-Genescà, M - Fernández, A - Boer, D -AF Elomari, Youssef - Norouzi, Masoud - Marin-Genesca, Marc - Fernandez, Alberto - Boer, Dieter -TI Integration of Solar Photovoltaic Systems into Power Networks: A - Scientific Evolution Analysis -SO SUSTAINABILITY -LA English -DT Review -DE renewable energy; solar photovoltaic (PV); power networks; bibliometric - analysis; science mapping -ID RENEWABLE ENERGY-SOURCES; LV DISTRIBUTION NETWORKS; VOLTAGE RISE - MITIGATION; BIBLIOMETRIC ANALYSIS; TECHNOECONOMIC ANALYSIS; DISTRIBUTED - GENERATION; SCIENTOMETRIC ANALYSIS; RURAL ELECTRIFICATION; INVERTER - TOPOLOGIES; GRID INTEGRATION -AB Solar photovoltaic (PV) systems have drawn significant attention over the last decade. One of the most critical obstacles that must be overcome is distributed energy generation. This paper presents a comprehensive quantitative bibliometric study to identify the new trends and call attention to the evolution within the research landscape concerning the integration of solar PV in power networks. The research is based on 7146 documents that were authored between 2000-2021 and downloaded from the Web of Science database. Using an in-house bibliometric tool, Bibliometrix R-package, and the open-source tool VOSviewer we obtained bibliometric indicators, mapped the network analysis, and performed a multivariate statistical analysis. The works that were based on solar photovoltaics into power networks presented rapid growth, especially in India. The co-occurrence analysis showed that the five main clusters, classified according to dimensions and significance, are (i) power quality issues that are caused by the solar photovoltaic penetration in power networks; (ii) algorithms for energy storage, demand response, and energy management in the smart grid; (iii) optimization, techno-economic analysis, sensitivity analysis, and energy cost analysis for an optimal hybrid power system; (iv) renewable energy integration, self-consumption, energy efficiency, and sustainable development; and (v) modeling, simulation, and control of battery energy storage systems. The results revealed that researchers pay close attention to "renewable energy", "microgrid", "energy storage", "optimization", and "smart grid", as the top five keywords in the past four years. The results also suggested that (i) power quality; (ii) voltage and frequency fluctuation problems; (iii) optimal design and energy management; and (iv) technical-economic analysis, are the most recent investigative foci that might be appraised as having the most budding research prospects. -C1 [Elomari, Youssef; Marin-Genesca, Marc; Boer, Dieter] Univ Rovira & Virgili, Dept Engn Mecan, Av Paisos Catalans 26, Tarragona 43007, Spain. - [Norouzi, Masoud; Fernandez, Alberto] Univ Rovira & Virgili, Dept Engn Quim, Av Paisos Catalans 26, Tarragona 43007, Spain. -C3 Universitat Rovira i Virgili; Universitat Rovira i Virgili -RP Boer, D (corresponding author), Univ Rovira & Virgili, Dept Engn Mecan, Av Paisos Catalans 26, Tarragona 43007, Spain. -EM youssef.elomari@urv.cat; masoud.norouzi@urv.cat; marc.marin@urv.cat; - alberto.fernandez@urv.cat; dieter.boer@urv.cat -RI Fernández-Sabater, Alberto/G-1214-2011; Fernandez, Alberto/G-1214-2011; - Marin-Genesca, Marc/H-1549-2015; Boer, Dieter/K-3162-2014; - Marin-Genescà, Marc/H-1549-2015; Norouzi, Masoud/ACN-7197-2022 -OI Fernandez, Alberto/0000-0002-1241-1646; Marin-Genesca, - Marc/0000-0002-7204-4526; Boer, Dieter/0000-0002-5532-6409; Norouzi, - Masoud/0000-0003-2943-5174; elomari, youssef/0000-0002-9907-4485 -FU Spanish Ministry of Economy and Competitiveness (MCIU/AEI/FEDER, UE) - [RTI2018-093849-B-C33]; Catalan Government [2017-SGR-1409]; Tarragona's - council [2021PGR-DIPTA-URV01]; Ministerio de Ciencia, Innovacion y - Universidades-Agencia Estatal de Investigacion (AEI) [RED2018-102431-T] -FX The authors would like to acknowledge financial support from the Spanish - Ministry of Economy and Competitiveness RTI2018-093849-B-C33 - (MCIU/AEI/FEDER, UE), the Catalan Government (2017-SGR-1409), and the - Tarragona's council (2021PGR-DIPTA-URV01). 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In the field of cybersecurity, cyber sextortion is a form of cybercrime that leverages privacy violations to exploit a victim. This study reviewed research developments on cyber sextortion progressively over time by looking at scientific productions, thematic developments, scholars' contributions, and the future thematic trajectory. A bibliometric approach to analyzing the data was applied, which covered 548 peer-reviewed articles, conference papers, and book chapters retrieved from the Scopus database. Results showed a growth trajectory on various thematic concerns in the cyber sextortion field, which has continued to gain traction since the year 2023. Notably, online child sexual abuse is a growing theme in cyber sextortion research. In addition, among other themes, adolescents, mental health, and dating violence are receiving interest among scholars in this field. Additionally, institutions and prolific scholars from countries such as the United States of America, Australia, and the United Kingdom have established research collaborations to improve understanding in this field. The results also showed that research is observed to be emerging from South Africa and Ghana in the African region. Overall, there is potential for more scientific publications and researchers from Africa to contribute to this growing field. The value this study holds is moving beyond deficit-based approaches to how adolescent youth can be resilient and protected from cyber sextortion. A call for a multidisciplinary approach that moves beyond deficit-based approaches toward resilient and autonomy-based approaches is encouraged so that adolescent youth are protected from exploitation. 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Sci.-Basel -PD JAN -PY 2025 -VL 14 -IS 1 -AR 12 -DI 10.3390/socsci14010012 -PG 31 -WC Social Sciences, Interdisciplinary -WE Emerging Sources Citation Index (ESCI) -SC Social Sciences - Other Topics -GA T5L5J -UT WOS:001405417600001 -OA gold -DA 2025-07-11 -ER - -PT J -AU Moradi, E -AF Moradi, Erfan -TI Mapping of Journal of Hospitality and Tourism Insights themes: a - retrospective overview -SO JOURNAL OF HOSPITALITY AND TOURISM INSIGHTS -LA English -DT Article -DE Bibliometric analysis; Hospitality and tourism; Intellectual structure; - Journal of Hospitality and Tourism Insights; Science mapping; Scopus -ID BIBLIOMETRIC ANALYSIS; SOCIAL MEDIA; DESTINATION IMAGE; BUSINESS; - FOUNDATIONS; COVID-19; INDUSTRY; SCIENCE; TRENDS; ISSUES -AB PurposeRecognising the literature of a field is vital for advancement in that field. Yet, there has not been a systematic analysis of recent publications published in the Journal of Hospitality and Tourism Insights (JHTI). Therefore, this research aims to do a bibliometric analysis of articles published in JHTI during the previous five years.Design/methodology/approachThis study used bibliometric techniques and indicators to analyse JHTI publications from 2018 to 2022. The data utilised in the study were obtained from Scopus and subsequently subjected to analysis through the Bibliometrix software.FindingsThe findings show good collaboration between the production components (country, institution and author) in JHTI. The co-occurrence analysis of keywords comprises five clusters; the co-citation analysis comprises six; and a group of articles connected with psychological aspects and areas such as motivation, attitude, customer engagement, place attachment and behavioural intention was the most remarkable cluster. Sharing economy, destination marketing, destination image and some, to an extent, social media and revenue management are just a few of the niche themes that have the potential to come up.Research limitations/implicationsThis study will be helpful as a roadmap for researchers in different fields who are interested in such studies, as well as for editorial board members and those who work in JHTI.Practical implicationsScholars and practitioners may benefit the most from this research by obtaining insight into the development of JHTI's research and the areas of the hospitality and tourism industries that need more study.Originality/valueThe current study is both necessary and valuable because it is the first to provide insight into the effectiveness and intellectual framework of the hospitality and tourism literature selected by the JHTI. -C1 [Moradi, Erfan] Tarbiat Modares Univ, Fac Humanities, Dept Sports Sci, Tehran, Iran. -C3 Tarbiat Modares University -RP Moradi, E (corresponding author), Tarbiat Modares Univ, Fac Humanities, Dept Sports Sci, Tehran, Iran. -EM erfan.moradi@modares.ac.ir -RI Moradi, Erfan/AAR-5863-2020 -OI Moradi, Erfan/0000-0002-6400-8058 -CR Agyeiwaah E, 2021, J HOSP TOUR INSIGHTS, DOI 10.1108/JHTI-09-2020-0169 - Ahn J, 2020, J HOSP TOUR INSIGHTS, V3, P607, DOI 10.1108/JHTI-02-2020-0022 - AJZEN I, 1991, ORGAN BEHAV HUM DEC, V50, P179, DOI 10.1016/0749-5978(91)90020-T - Ajzen I., 1985, ACTION CONTROL COGNI, P11, DOI [10.1007/978-3-642-69746-32, DOI 10.1007/978-3-642-69746-3_2] - Ali F, 2022, J HOSP TOUR TECHNOL, V13, P781, DOI 10.1108/JHTT-11-2022-332 - Amoako GK, 2023, J HOSP TOUR INSIGHTS, V6, P110, DOI 10.1108/JHTI-06-2021-0141 - Amoako GK, 2019, J HOSP TOUR INSIGHTS, V2, P326, DOI 10.1108/JHTI-07-2018-0039 - Ampong GOA, 2020, J HOSP TOUR INSIGHTS, DOI 10.1108/JHTI-03-2020-0034 - Ampountolas A, 2019, J HOSP TOUR INSIGHTS, V2, P75, DOI 10.1108/JHTI-07-2018-0040 - ANDERSON JC, 1988, PSYCHOL BULL, V103, P411, DOI 10.1037/0033-2909.103.3.411 - Aria M., 2020, Science mapping analysis with bibliometrix R-package: An example - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Atasoy B, 2022, J HOSP TOUR INSIGHTS, V5, P1118, DOI 10.1108/JHTI-02-2021-0047 - Baggio R, 2017, TOUR REV, V72, P120, DOI 10.1108/TR-01-2017-0008 - Baker HK, 2021, J FORECASTING, V40, P577, DOI 10.1002/for.2731 - Baloglu S, 1999, ANN TOURISM RES, V26, P868, DOI 10.1016/S0160-7383(99)00030-4 - Barbe D, 2018, J HOSP TOUR INSIGHTS, V1, P258, DOI 10.1108/JHTI-02-2018-0009 - Bastidas-Manzano AB, 2021, J HOSP TOUR RES, V45, P529, DOI 10.1177/1096348020967062 - Benckendorff P, 2013, ANN TOURISM RES, V43, P121, DOI 10.1016/j.annals.2013.04.005 - Bogan E, 2019, J HOSP TOUR INSIGHTS, V2, P391, DOI 10.1108/JHTI-12-2018-0089 - Casadei P, 2023, EUR PLAN STUD, V31, P2531, DOI 10.1080/09654313.2022.2158722 - Çelik S, 2019, J HOSP TOUR INSIGHTS, V2, P425, DOI 10.1108/JHTI-01-2019-0005 - Chen CF, 2007, TOURISM MANAGE, V28, P1115, DOI 10.1016/j.tourman.2006.07.007 - Chin WW, 1998, MIS QUART, V22, pVII - Crompton J. 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Hosp. Tour. Insights -PD APR 30 -PY 2024 -VL 7 -IS 2 -BP 1211 -EP 1237 -DI 10.1108/JHTI-12-2022-0638 -EA MAY 2023 -PG 27 -WC Hospitality, Leisure, Sport & Tourism -WE Emerging Sources Citation Index (ESCI) -SC Social Sciences - Other Topics -GA PV6A6 -UT WOS:000986968500001 -DA 2025-07-11 -ER - -PT J -AU Hernández-González, V - Conesa-Milian, E - Jové-Deltell, C - Pano-Rodríguez, A - Legaz-Arrese, A - Reverter-Masia, J -AF Hernandez-Gonzalez, Vicenc - Conesa-Milian, Enric - Jove-Deltell, Carme - Pano-Rodriguez, Alvaro - Legaz-Arrese, Alejandro - Reverter-Masia, Joaquin -TI Global research trends on cardiac troponin and physical activity among - pediatric populations: a bibliometric analysis and science mapping study -SO FRONTIERS IN PEDIATRICS -LA English -DT Article -DE cardiac troponin; pediatric; bibliometrics; productivity; network - analysis; Web of Science; sports science -ID INDIVIDUAL VARIABILITY; ENDURANCE EXERCISE; BIOMARKER RELEASE; T - RELEASE; HEALTH; COLLABORATION; AMATEUR; FUTURE; ELITE; FIELD -AB Background Cardiac troponin (cTn) is a reliable marker for evaluating myocardial damage. cTn is a very specific protein involved in myocardial injury, and it is a key factor in the diagnosis of coronary syndromes. Bibliometric analysis was applied in the present work, with the main goal of evaluating global research on the topic of cardiac troponin in pediatric populations.Methods Publications about cardiac troponin and physical activity in pediatric populations were retrieved from the Social Sciences Citation Index (SSCI) and the Science Citation Index Expanded (SCIE) of the Web of Science Core Collection, and they were then analyzed. The study was able to identify the key bibliometric indicators, such as publications, keywords, authors, countries, institutions, and journals. For the analysis, VOSviewer, R-based Bibliometrix (4.2.2), and MapChart were used.Results Initially, 98 documents were identified; however, once inclusion and exclusion criteria were applied, the number of documents decreased to 88. The search yielded 79 original research articles and 9 reviews, almost all of which were published in the past 2 decades. The total number of citations (Nc) of the retrieved publications was 1,468, and the average number of citations per article (Na) was 16.68. In general, 508 authors were found to have participated in research about troponin; they were associated with 256 institutions, and their work was published in 65 different journals from around the world. The authors hailed from 30 countries and/or regions. The year 2022 was the most productive year for the publication of the selected documents. The bibliometric analysis provided information regarding levels of cooperation among authors and institutions. In fact, China, the United States, and England were the most productive nations, and the journal with the greatest number of publications on the topic was Pediatric Cardiology.Summary The number of publications and the trend line show that research on this topic has not yet reached a stage of maturity. There are referent investigators, countries, and institutions that have laid the foundations for subsequent studies on the analyzed topic. -C1 [Hernandez-Gonzalez, Vicenc; Conesa-Milian, Enric; Jove-Deltell, Carme; Pano-Rodriguez, Alvaro; Reverter-Masia, Joaquin] Univ Lleida, Human Movement Res Grp RGHM, Lleida, Spain. - [Hernandez-Gonzalez, Vicenc; Conesa-Milian, Enric; Jove-Deltell, Carme; Pano-Rodriguez, Alvaro; Reverter-Masia, Joaquin] Univ Lleida, Phys Educ & Sport Sect, Lleida, Spain. - [Legaz-Arrese, Alejandro] Univ Zaragoza, Fac Hlth & Sport Sci, Sect Phys Educ & Sports, Zaragoza, Spain. -C3 Universitat de Lleida; Universitat de Lleida; University of Zaragoza -RP Hernández-González, V (corresponding author), Univ Lleida, Human Movement Res Grp RGHM, Lleida, Spain.; Hernández-González, V (corresponding author), Univ Lleida, Phys Educ & Sport Sect, Lleida, Spain. -EM vicenc.hernandez@udl.cat -RI ; De Pano Rodríguez, Álvaro/AAD-1335-2020; Hernández-González, - Vicenç/B-4706-2016; Hernandez-Gonzalez, Vicenc/B-4706-2016 -OI Conesa Milian, Enric/0009-0000-1435-1598; De Pano Rodriguez, - Alvaro/0000-0002-6816-6571; Hernandez-Gonzalez, - Vicenc/0000-0003-3201-3298 -FU State Program for Research, Development and InnovationOriented to the - Challenges of Society -FX No Statement Available -CR Adams J, 2013, NATURE, V497, P557, DOI 10.1038/497557a - Aleixandre Benavent R., 2000, Trastor Adict, V2, P264 - Aleixandre-Benavent R, 2013, REV NEUROLOGIA, V57, P157, DOI 10.33588/rn.5704.2013125 - Arbé AA, 2015, MED CLIN-BARCELONA, V145, P258, DOI 10.1016/j.medcli.2014.11.004 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Aronson Jeffrey K, 2017, Curr Protoc Pharmacol, V76, DOI 10.1002/cpph.19 - Banerjee S, 2022, INDIAN J ORTHOP, V56, P762, DOI 10.1007/s43465-022-00604-9 - Barabási AL, 2002, PHYSICA A, V311, P590, DOI 10.1016/S0378-4371(02)00736-7 - Bohn MK, 2019, CLIN CHEM, V65, P589, DOI 10.1373/clinchem.2018.299156 - Bradford S.C., 1934, ENGINEERING, V137, P85 - Bruni A, 2021, AM J ORTHOD DENTOFAC, V159, pE341, DOI 10.1016/j.ajodo.2020.11.029 - Cáceres Castellanos Gustavo, 2014, Rev. 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Practitioner Health - Wu AHB, 2018, CLIN CHEM, V64, P645, DOI 10.1373/clinchem.2017.277186 - Yang L, 2013, SCIENTOMETRICS, V96, P133, DOI 10.1007/s11192-012-0911-6 - Yu YT, 2020, ANN TRANSL MED, V8, DOI 10.21037/atm-20-4235 - Zheng TL, 2016, SCIENTOMETRICS, V109, P53, DOI 10.1007/s11192-016-2004-4 - Zhu YL, 2021, ORTHOP TRAUMATOL-SUR, V107, DOI 10.1016/j.otsr.2021.102988 -NR 88 -TC 1 -Z9 1 -U1 2 -U2 9 -PU FRONTIERS MEDIA SA -PI LAUSANNE -PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND -SN 2296-2360 -J9 FRONT PEDIATR -JI Front. Pediatr. -PD FEB 5 -PY 2024 -VL 12 -AR 1285794 -DI 10.3389/fped.2024.1285794 -PG 16 -WC Pediatrics -WE Science Citation Index Expanded (SCI-EXPANDED) -SC Pediatrics -GA IB3Q1 -UT WOS:001163826200001 -PM 38374876 -OA gold, Green Published -DA 2025-07-11 -ER - -PT J -AU Asif, R - Nasir, A -AF Asif, Rabia - Nasir, Adeel -TI Financial stability nexus of Islamic banks: an influential and - intellectual science mapping structure -SO JOURNAL OF ISLAMIC ACCOUNTING AND BUSINESS RESEARCH -LA English -DT Article -DE Financial stability; Islamic; Banks; CAMELS; Bibliometric; CAMEL - analysis; Bibliometric analysis -ID CORPORATE SOCIAL-RESPONSIBILITY; CONVENTIONAL BANKS; EMPIRICAL-EVIDENCE; - BIBLIOMETRIC ANALYSIS; EFFICIENCY; PERFORMANCE; BUSINESS; RISK; - DETERMINANTS; DISCLOSURE -AB PurposeThis study aims to provide a comprehensive bibliometric investigation of the antecedents to financial stability in Islamic banking, a transition economy with a volatile stock market focusing on banks following the Shariah approach. Design/methodology/approachThe data for this analysis was extracted from the Scopus database, which combines a comprehensively crafted abstract and citation database with augmented data and linked scholarly works across various disciplines. It quickly finds relevant research and provides access to reliable data and analytical tools. This study deploys "bibliometrix 3.0," a biblioshiny R-package for influential structure and the VOS viewer for intellectual structure. FindingsThe investigation's main findings revealed that 1,910 documents were published from 1987 to 2022. Published manuscripts received 39,050 citations, with an average of 10.18 citations per year. However, the instructed empirical research was experienced during 2009 and 2020, while earlier periods (1987-2008) were relatively inactive where banking was considered protective in the presence of BASEL-II capital accords regulations. While the International Journal of Bank Market has been at the top of the list to publish articles related to the area under investigation, the Journal of Banking and Finance is ranked one of the most cited articles. Malaysia has been at the top of the list of countries to research Islamic Sharia compliance principles in the banking industry, and International Islamic University Malaysia has produced enough evidence in this regard. The intellectual structure provided essential foundations for future research, and the bibliometric coupling approach was used. Practical implicationsWhile most of the banking research has been conducted to determine the banking business efficiency, risk and profitability, little focus is given to financial stability and that too concerning the Islamic banks. Therefore, researchers need to investigate this horizon from an Islamic banking point of view and focus on key issues that discriminate between Islamic and conventional banks in determining their stability level. Originality/valueBriefly, to the best of the authors' knowledge, this study would be the first to provide bibliometric information about financial stability keeping in view the sample data from banks with the Shariah approach. 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Islamic Account. Bus. Res. -PD MAR 29 -PY 2024 -VL 15 -IS 4 -BP 569 -EP 589 -DI 10.1108/JIABR-07-2022-0167 -EA MAY 2023 -PG 21 -WC Business, Finance -WE Emerging Sources Citation Index (ESCI) -SC Business & Economics -GA MF1F4 -UT WOS:000984021000001 -DA 2025-07-11 -ER - -PT J -AU Al Rousan, R - Khasawneh, N - Sujood -AF Al Rousan, Ramzi - Khasawneh, Nermin - Sujood -TI Mapping 30 years of tourism and hospitality research in the Arab world: - a review based on bibliometric analysis -SO TOURISM REVIEW -LA English -DT Review -DE Tourism; Hospitality; Arab world; Bibliometric analysis; Keywords - analysis; Thematic analysis; Network analysis -AB Purpose - The Arab world has witnessed a remarkable surge in the growth of its tourism and hospitality (T&H) industry, positioning it as a vital cornerstone for sustainable development. However, an exclusive bibliometric analysis of T&H research contributed by the Arab world has not yet been conducted in the past 30 years, that is, 1993-2022. Therefore, the purpose of this study is to provide a first-of-its-kind bibliometric assessment and visualization of T&H research produced by the Arab world spanning from 1993 to 2022. Design/methodology/approach - A comprehensive collection of 1,327 scientific publications related to T&H research contributed by the Arab world was acquired from the Web of Science Core Collection database. To perform a large-scale bibliometric analysis, encompassing performance analysis, science mapping and network analysis, this study used state-of-the-art analytical tools, namely, Bibliometrix package of R Studio and VOSviewer. Findings - The findings of this study show that the Arab world's research on T&H has significantly surged since COVID-19, contributing nearly half (50. 56%) of the total literature in the T&H domain between 2020 and 2022. Elshaer IA (Suez Canal University, Egypt) emerged as the most productive author, while Nusair K (Sultan Qaboos University, Oman) was identified as the most impactful author in the T&H domain in the Arab world. The most productive journal was found to be Sustainability (MDPI), while Tourism Management (Elsevier) was identified as the most impactful journal in the field of T&H. Furthermore, the thematic analysis highlights that research themes in T&H are not static but rather constantly evolving in response to dynamic changes in the industry, such as emerging trends, shifts in tourist preferences and the impact of global events like the COVID-1 9 pandemic. Originality/value - To the best of the authors' knowledge, this is the first bibliometric analysis of T&H research contributed by the Arab world, specifically covering the period from 1993 to 2022. This study's findings can inform the development of strategies and policies for the sustainable and competitive growth of the T&H industry in the Arab world. This study highlights the importance of continued research and collaboration among industry professionals, academics and policymakers to promote innovation and drive positive change in the T&H sector in the Arab world. -C1 [Al Rousan, Ramzi] Hashemite Univ, Queen Rania Fac Tourism & Heritage, Dept Sustainable Tourism, Zarqa, Jordan. - [Khasawneh, Nermin] Queen Rania Fac Tourism & Heritage, Dept Sustainable Tourism, Zarqa, Jordan. - [Sujood] Jamia Millia Islamia, Dept Tourism & Hospitality Management, New Delhi, India. -C3 Hashemite University; Jamia Millia Islamia -RP Sujood (corresponding author), Jamia Millia Islamia, Dept Tourism & Hospitality Management, New Delhi, India. -EM sjdkhancool@gmail.com -RI , Dr. Sujood/AAY-9219-2021; Al Rousan, Ramzi/HHZ-1058-2022 -OI , Dr. SUJOOD/0000-0001-9475-2585 -CR Algassim A., 2021, Journal of Association of Arab Universities for Tourism and Hospitality, V20, P129, DOI [DOI 10.21608/JAAUTH.2021.55964.1108, 10.21608/jaauth.2021.55964.1108] - Almuhrzi H., 2017, TOURISM ARAB WORLD I - Alsharari NM, 2018, INT J EDUC MANAG, V32, P359, DOI 10.1108/IJEM-04-2017-0082 - Hernández JB, 2017, EURASIA J MATH SCI T, V13, P1539, DOI 10.12973/eurasia.2017.00684a - Bhutia P.D., 2023, SKIFT 15 FEBRUARY - Correia A, 2022, CURR ISSUES TOUR, V25, P995, DOI 10.1080/13683500.2021.1918069 - Das A, 2024, TOUR REV, V79, P622, DOI 10.1108/TR-08-2022-0387 - Donthu N, 2021, J BUS RES, V133, P285, DOI 10.1016/j.jbusres.2021.04.070 - Dwivedi YK, 2023, J BUS RES, V161, DOI 10.1016/j.jbusres.2023.113839 - Fusco F., 2020, BMC HEALTH SERV RES, V20, P16 - Gaviria-Marin M, 2019, TECHNOL FORECAST SOC, V140, P194, DOI 10.1016/j.techfore.2018.07.006 - Isik C, 2022, SUSTAINABILITY-BASEL, V14, DOI 10.3390/su14137889 - Klingmann A, 2023, J PLACE MANAG DEV, V16, P45, DOI 10.1108/JPMD-06-2021-0062 - Knani M, 2022, INT J HOSP MANAG, V107, DOI 10.1016/j.ijhm.2022.103317 - Lew AA, 2020, TOURISM GEOGR, V22, P455, DOI 10.1080/14616688.2020.1770326 - Liao HC, 2022, ECON RES-EKON ISTRAZ, DOI 10.1080/1331677X.2022.2150871 - Mauleón-Méndez E, 2020, J INTELL FUZZY SYST, V38, P5565, DOI 10.3233/JIFS-179647 - Menon D, 2022, J HOSP LEIS SPORT TO, V30, DOI 10.1016/j.jhlste.2021.100360 - Muritala BA, 2020, SUSTAINABILITY-BASEL, V12, DOI 10.3390/su12239977 - Naseem S, 2021, ECONOMIES, V9, DOI 10.3390/economies9030117 - Nusair K, 2019, INT J CONTEMP HOSP M, V31, P2691, DOI 10.1108/IJCHM-06-2018-0489 - Okumus B, 2018, INT J HOSP MANAG, V73, P64, DOI 10.1016/j.ijhm.2018.01.020 - Ozguzel S., 2020, Journal of Social Sciences and Humanities Research, V8, P61 - Ratten V, 2021, STRATEG CHANG, V30, P91, DOI 10.1002/jsc.2392 - Santos LL, 2020, SUSTAINABILITY-BASEL, V12, DOI 10.3390/su12218852 - Shekhar, 2022, J FAM BUS MANAG, V12, P367, DOI 10.1108/JFBM-10-2021-0121 - Shin HH, 2022, INT J CONTEMP HOSP M, DOI 10.1108/IJCHM-03-2022-0376 - Skirka H., 2023, NATIONAL 0118 - Syed A., 2022, ARAB NEWS 29 NOVEMBE - Tabash MI, 2023, TOUR REV, V78, P1004, DOI 10.1108/TR-07-2022-0347 - Vatankhah S, 2023, INT J CONTEMP HOSP M, V35, P2590, DOI 10.1108/IJCHM-05-2022-0643 - Wagner CS, 2017, SCIENTOMETRICS, V110, P1633, DOI 10.1007/s11192-016-2230-9 - World Travel & Tourism Council (WTTC), 2022, MIDDL E TRAV TOUR SE - World Travel & Tourism Council (WTTC), 2022, GLOB EC IMP TRENDS W -NR 34 -TC 2 -Z9 2 -U1 5 -U2 23 -PU EMERALD GROUP PUBLISHING LTD -PI Leeds -PA Floor 5, Northspring 21-23 Wellington Street, Leeds, W YORKSHIRE, - ENGLAND -SN 1660-5373 -EI 1759-8451 -J9 TOUR REV -JI Tour. Rev. -PD AUG 2 -PY 2024 -VL 79 -IS 6 -BP 1280 -EP 1298 -DI 10.1108/TR-04-2023-0201 -EA NOV 2023 -PG 19 -WC Hospitality, Leisure, Sport & Tourism -WE Social Science Citation Index (SSCI) -SC Social Sciences - Other Topics -GA A4Q5I -UT WOS:001098175000001 -DA 2025-07-11 -ER - -PT J -AU Kushwaha, D - Talib, F - Asjad, M -AF Kushwaha, Dilip - Talib, Faisal - Asjad, Mohammad -TI The intellectual structure of research on environmental sustainability - 4.0 in manufacturing: a bibliometric analysis and future research - directions -SO ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY -LA English -DT Article; Early Access -DE Author keywords co-occurrences; Co-citation network; Content analysis; - Environmental sustainability 4.0; Industry 4.0; VOSviewer -ID SUPPLY CHAIN MANAGEMENT; CIRCULAR ECONOMY; CLEANER PRODUCTION; CITATION - ANALYSIS; INDUSTRY; SCIENCE; COCITATION; TECHNOLOGIES; PERFORMANCE; - DISCIPLINE -AB Manufacturing firms are paying more attention to environmental sustainability, and therefore, they intend to incorporate Industry 4.0 tools and techniques that ensure future manufacturing, product safety, and environmental sustainability. This study explores the current status and trend of environmental sustainability in manufacturing organisations in Industry 4.0 and discusses future research directions for implementing these digital tools. Therefore, this study identifies, maps, synthesises, and analyses the literature on environmental sustainability 4.0 practices in manufacturing organisations through performance analysis and science mapping. This study employed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) statement as a review norm, and information was collected as such. This paper systematically reviewed 314 English-language articles published in peer-reviewed journals in the scientific databases Scopus and the Web of Science (WOS) between 2013 and October 2023. The articles were combined, and duplicates were removed using an open-source tool, RStudio. We analysed bibliometric networks using the Biblioshiny Bibliometrix R-package in RStudio and the VOSviewer software application, which allows for creating, visualising, and interpreting maps based on any network data. This review determined the top contributing authors, nations, sources, and essential study topics. In addition, the most influential and prestigious documents based on citations and PageRank were identified and compared. Furthermore, this paper used keyword analysis to explore trends in study topics and themes and discussed the five research theme clusters obtained. Co-citation and content analysis were used to outline the intellectual structure of the discipline and pinpoint deficiencies. The gist of 49 papers inside the identified clusters is further analysed meticulously, and four primary intellectual structures were identified as Sustainable Manufacturing and Industry 4.0 relationship; Future Scope of Industry 4.0 for Sustainable Manufacturing; Impacts, Challenges, and Opportunities of Industry 4.0 for Sustainable Manufacturing; and Harmonizing Different Models with Industry 4.0: A Path to Sustainable Manufacturing. Over 50% of the scholarly work concerning environmental sustainability 4.0 within the manufacturing sector elucidates the effects, challenges, opportunities, and future possibilities of Industry 4.0. This is the first systematic literature review-cum-bibliographic study on Environmental Sustainability 4.0, which integrates three crucial issues currently being debated: Industry 4.0, environmental sustainability, and manufacturing, and provides in-depth field analysis. Based on the present review, this article suggests five potential future research issues and various research questions for investigation. New researchers may benefit from these findings and strengthen any intellectual field according to their interests and requirements. Overall, the outcomes construct an impressive starting point for additional research for decision-makers, managers, practitioners, and scholars in this domain. -C1 [Kushwaha, Dilip; Talib, Faisal] Aligarh Muslim Univ, Zakir Husain Coll Engn & Technol, Fac Engn & Technol, Dept Mech Engn, Aligarh 202002, India. - [Asjad, Mohammad] Jamia Millia Islamia, Dept Mech Engn, New Delhi 110025, India. -C3 Zakir Husain College Of Engineering & Technology; Aligarh Muslim - University; Jamia Millia Islamia -RP Talib, F (corresponding author), Aligarh Muslim Univ, Zakir Husain Coll Engn & Technol, Fac Engn & Technol, Dept Mech Engn, Aligarh 202002, India. -EM ftalib77@gmail.com -CR Abd Aziz N, 2021, J CLEAN PROD, V296, DOI 10.1016/j.jclepro.2021.126401 - Adami L, 2021, SUSTAINABILITY-BASEL, V13, DOI 10.3390/su13020925 - Adams D, 2021, SUSTAIN PROD CONSUMP, V28, P1491, DOI 10.1016/j.spc.2021.08.019 - Aghbashlo M, 2021, PROG ENERG COMBUST, V85, DOI 10.1016/j.pecs.2021.100904 - Ahirwal J, 2021, SCI TOTAL ENVIRON, V770, DOI 10.1016/j.scitotenv.2021.145292 - 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M. - Zhang, Wenlan - Ma, Hongliang - Feng, Zhichao -TI Professional development for STEM educators: A bibliometric analysis of - the recent progress -SO REVIEW OF EDUCATION -LA English -DT Review -DE bibliometric analysis; citation analysis; educational research trend; - science mapping; scientific collaboration; STEM education; teacher - professional development -ID PEDAGOGICAL CONTENT KNOWLEDGE; SCIENCE TEACHERS; TECHNOLOGY INTEGRATION; - SELF-EFFICACY; TPACK; CONCEPTIONS; ATTITUDES; ROBOTICS; UNDERSTAND; - CLASSROOMS -AB STEM teacher professional development (STEM-TPD) has become a hot topic of educational research. To evaluate the main characteristics, status and trends of this educational field and to provide new insights for future studies, this review applies a bibliometric analysis of relevant publications. The Web of Science (WoS) core collection database was used as the source of bibliographic data for the period 2011-2021; specifically, 776 articles published in 232 journals were selected for this review. The bibliometric analysis was then carried out using Bibliometrix and VOSviewer to explore trends and patterns in the STEM-TDP literature. It is essential to note that the analysis does not account for the quality of the selected studies. However, it presents the results using various perspectives such as citation, co-citation, spatial and lexical networks based on frequencies, network analysis and descriptive patterns. The findings show that the number of relevant publications has grown significantly in recent years, in particular from 2015 to 2021. The findings, based on citation metrics, highlight the most influential authors, institutions and journals in the area. Authors from different countries have contributed to this research area, but there is a low volume of international collaboration among them. The analysis also reveals the dynamic changes in trends, keywords and themes in this research area. The review concludes with some recommendations for future research, and the suggested implications may also benefit other stakeholders in STEM education. Rationale for the studyContext and Implications Implications for researchers, practitioners and policy makersWhy do the new findings matter? STEM education has garnered researchers' interest over the past two decades, but there are few reviews of STEM teacher professional development (STEM-TPD) publications. Therefore, this bibliometric review sought to investigate the expansion of STEM-TPD research. It also serves as a roadmap for future TPD research in STEM education.This comprehensive bibliometric study analysed 776 research publications on STEM-TPD that were published in journals that were indexed by WoS. The findings shed light on recent developments, patterns and trends in STEM-TPD research, as well as international collaboration in STEM-TPD research.The overall findings may benefit the researchers, editorial board, and publishers to focus more on some emerging research themes, which can guide the focus of future research. STEM researchers should consider conducting more ambitious, high-quality empirical research that is likely to yield robust results. They can investigate higher-order thinking skills and other issues related to equity, gender inequality, and teacher attrition. The results also inspire researchers and research institutions to boost international collaboration. Similarly, policy makers and higher education institutions should implement more reforms to educational policies and teacher preparation programmes to improve and sustain STEM education. -C1 [Ahmed, Salah A. M.; Zhang, Wenlan; Ma, Hongliang; Feng, Zhichao] Shaanxi Normal Univ, Sch Educ, Xian, Shaanxi, Peoples R China. - [Zhang, Wenlan] Shaanxi Normal Univ, Sch Educ, 199 Changan South Rd, Xian 710062, Peoples R China. -C3 Shaanxi Normal University; Shaanxi Normal University -RP Zhang, WL (corresponding author), Shaanxi Normal Univ, Sch Educ, 199 Changan South Rd, Xian 710062, Peoples R China. -EM wenlan19@163.com -RI ; Feng, zhi/F-2264-2017; Ma, Hongliang/AEY-5033-2022; AHMED, - SALAH/AAU-6975-2020 -OI Ma, Hongliang/0000-0001-9177-8069; -CR Salami MK, 2017, INT J TECHNOL DES ED, V27, P63, DOI 10.1007/s10798-015-9341-0 - Allen CD, 2015, J TEACH EDUC, V66, P136, DOI 10.1177/0022487114560646 - Alvarado LE, 2020, TECHTRENDS, V64, P498, DOI 10.1007/s11528-020-00483-7 - Oviedo-García MA, 2021, RES EVALUAT, V30, P405, DOI 10.1093/reseval/rvab020 - Annetta L, 2014, INFORM SCIENCES, V264, P61, DOI 10.1016/j.ins.2013.10.028 - [Anonymous], 2009, Engineering in K-12 education: Understanding the status and improving the prospects, DOI DOI 10.17226/12635 - Aparicio G, 2021, J FURTH HIGH EDUC, V45, P540, DOI 10.1080/0309877X.2020.1795092 - Aria M, 2017, J INFORMETR, V11, P959, DOI 10.1016/j.joi.2017.08.007 - Asempapa RS, 2021, SCHOOL SCI MATH, V121, P85, DOI 10.1111/ssm.12448 - Aslam F, 2018, J EDUC TEACHING, V44, P58, DOI 10.1080/02607476.2018.1422618 - Assefa SG, 2013, J AM SOC INF SCI TEC, V64, P2513, DOI 10.1002/asi.22917 - Avila-Garzon C, 2021, CONTEMP EDUC TECHNOL, V13, DOI 10.30935/cedtech/10865 - Barak M, 2018, COMPUT EDUC, V121, P89, DOI 10.1016/j.compedu.2018.02.014 - Bell RL, 2013, J RES SCI TEACH, V50, P348, DOI 10.1002/tea.21075 - Bhattacharyya SS, 2020, INT J SOCIOL SOC POL, V40, P1551, DOI 10.1108/IJSSP-12-2019-0263 - Blanchard MR, 2016, EDUC RESEARCHER, V45, P207, DOI 10.3102/0013189X16644602 - BROADUS RN, 1987, SCIENTOMETRICS, V12, P373, DOI 10.1007/BF02016680 - Brophy S, 2008, J ENG EDUC, V97, P369, DOI 10.1002/j.2168-9830.2008.tb00985.x - Bybee RW., 2013, A case for STEM education - Carpenter SL, 2019, SCHOOL SCI MATH, V119, P275, DOI 10.1111/ssm.12340 - Cavlazoglu B, 2018, J SCI EDUC TECHNOL, V27, P348, DOI 10.1007/s10956-018-9728-2 - Cavlazoglu B, 2017, J EDUC RES, V110, P239, DOI 10.1080/00220671.2016.1273176 - Çetin M, 2020, EARLY CHILD DEV CARE, V190, P1323, DOI 10.1080/03004430.2018.1534844 - Chai CS, 2019, ASIA-PAC EDUC RES, V28, P5, DOI 10.1007/s40299-018-0400-7 - Chang JN, 2020, CULT STUD SCI EDUCAT, V15, P423, DOI 10.1007/s11422-019-09955-6 - Chen YH, 2015, J COMPUT ASSIST LEAR, V31, P330, DOI 10.1111/jcal.12095 - Christian KB, 2021, INT J STEM EDUC, V8, DOI 10.1186/s40594-021-00284-1 - Cividatti L. 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Educ. -PD APR -PY 2023 -VL 11 -IS 1 -AR e3392 -DI 10.1002/rev3.3392 -PG 33 -WC Education & Educational Research -WE Emerging Sources Citation Index (ESCI) -SC Education & Educational Research -GA F9AE9 -UT WOS:000985193200007 -DA 2025-07-11 -ER - -EF \ No newline at end of file diff --git a/test_etl_pipeline.py b/test_etl_pipeline.py new file mode 100644 index 000000000..d887766e4 --- /dev/null +++ b/test_etl_pipeline.py @@ -0,0 +1,176 @@ +""" +End-to-end test harness for the source-agnostic ETL pipeline. + +This script is the *execution evidence* required by the exam brief: it proves +that the standardized DataFrame produced by :class:`BibliometrixETL` lets the +assigned analytical functions run without crashing, regardless of the original +source database (Scopus, Dimensions, PubMed, Web of Science). + +For every source it: + +1. Runs the full ETL (Extract -> Transform -> Validate) and prints a short + schema report (row count, PY coverage, multi-value list lengths). +2. Wraps the resulting DataFrame in :class:`DataWrapper`, which mimics the + Shiny ``reactive.Value`` interface (``.get()`` / ``.set()``) that the + analytical functions expect — exactly how ``app.py`` calls them. +3. Invokes each of the three assigned analytical functions with the same + default arguments the dashboard uses, and reports PASS / FAIL. + +Run with: python test_etl_pipeline.py +""" + +import os +import sys +import traceback + +sys.path.insert(0, os.path.dirname(os.path.abspath(__file__))) + +from www.services.etl_pipeline import BibliometrixETL # noqa: E402 +from functions.get_annualproduction import get_annual_production # noqa: E402 +from functions.get_cocitation import get_co_citation # noqa: E402 +from functions.get_clusteringcoupling import get_clustering_coupling # noqa: E402 + + +class DataWrapper: + """Minimal stand-in for the Shiny ``reactive.Value`` object. + + The analytical functions in ``functions/`` are written to receive the + reactive value holder and call ``.get()`` on it (and sometimes ``.set()``). + In a headless test we replicate that contract with this tiny wrapper. + """ + + def __init__(self, dataframe): + self._dataframe = dataframe + + def get(self): + return self._dataframe + + def set(self, dataframe): + self._dataframe = dataframe + + +# (source_key, file_path, file_type) +SOURCES = [ + ("scopus", "sources/Scopus/Scopus.csv", ".csv"), + ("dimensions", "sources/Dimensions/Dimensions.xlsx", ".xlsx"), + ("pubmed", "sources/PubMed/pubmed-allergicrh-set.txt", ".txt"), + ("web_of_science", "sources/Web_of_Science/WoS.txt", ".txt"), +] + + +def _list_avg(series): + lengths = [len(x) for x in series if isinstance(x, list)] + return round(sum(lengths) / len(lengths), 2) if lengths else 0.0 + + +def schema_report(source, df): + py_filled = (df["PY"].astype(str).str.strip() != "").sum() + print(f" rows={len(df):<5} cols={df.shape[1]} " + f"PY_filled={py_filled}/{len(df)} " + f"AU_avg={_list_avg(df['AU'])} CR_avg={_list_avg(df['CR'])} " + f"DE_avg={_list_avg(df['DE'])}") + + +def _has_references(df): + """True if the dataset carries any cited-reference data (CR field).""" + if "CR" not in df.columns: + return False + return df["CR"].apply(lambda x: len(x) if isinstance(x, list) else 0).sum() > 0 + + +def run_assigned_functions(wrapped, df): + """Call the three assigned functions with the dashboard's default args. + + Co-citation and bibliographic coupling are computed *from cited references*. + Sources that do not export a reference list (PubMed, Dimensions) therefore + cannot produce these networks: we mark them N/A rather than FAIL, since the + brief only requires functions not to crash *when the raw data contains the + necessary underlying information*. + """ + outcomes = {} + refs_available = _has_references(df) + + # 1) get_annual_production(df_wrapper) + try: + get_annual_production(wrapped) + outcomes["get_annual_production"] = ("PASS", None) + except Exception: + outcomes["get_annual_production"] = ("FAIL", traceback.format_exc()) + + # 2) get_co_citation(...) — defaults taken from app.py's co-citation modal + if not refs_available: + outcomes["get_co_citation"] = ("N/A", "source has no cited-references (CR) data") + else: + try: + get_co_citation( + df=wrapped, field="CR", sep=";", + cocit_network_layout="auto", cocit_clustering_algorithm="walktrap", + cocit_repulsion=0.1, cocit_shape="dot", cocit_shadow="No", + cocit_curved="No", citlabelsize=2, citedgesize=2, + citlabel_cex="Yes", citNodes=50, cit_isolates="yes", citedges_min=2, + ) + outcomes["get_co_citation"] = ("PASS", None) + except Exception: + outcomes["get_co_citation"] = ("FAIL", traceback.format_exc()) + + # 3) get_clustering_coupling(...) — defaults taken from app.py's coupling modal + if not refs_available: + outcomes["get_clustering_coupling"] = ("N/A", "source has no cited-references (CR) data") + else: + try: + get_clustering_coupling( + wrapped, "documents", "CR", False, "local", "ID", 1, + 250, 5, 3, 0.3, 0, "walktrap", + ) + outcomes["get_clustering_coupling"] = ("PASS", None) + except Exception: + outcomes["get_clustering_coupling"] = ("FAIL", traceback.format_exc()) + + return outcomes + + +def main(): + etl = BibliometrixETL() + failures = [] + summary = [] + + for source, path, file_type in SOURCES: + print(f"\n{'=' * 70}\nSOURCE: {source}\n{'=' * 70}") + if not os.path.exists(path): + print(f" [skip] file not found: {path}") + continue + try: + df = etl.run(path, source, file_type) + except Exception: + print(f" [ETL FAILED]\n{traceback.format_exc()}") + failures.append((source, "ETL", traceback.format_exc())) + continue + + schema_report(source, df) + + outcomes = run_assigned_functions(DataWrapper(df), df) + for fn_name, (status, tb) in outcomes.items(): + note = f" ({tb})" if status == "N/A" else "" + print(f" {status:4} | {fn_name}{note}") + summary.append((source, fn_name, status)) + if status == "FAIL": + failures.append((source, fn_name, tb)) + + # Final summary + print(f"\n{'=' * 70}\nSUMMARY\n{'=' * 70}") + passed = sum(1 for _, _, s in summary if s == "PASS") + na = sum(1 for _, _, s in summary if s == "N/A") + failed = sum(1 for _, _, s in summary if s == "FAIL") + print(f" PASS={passed} N/A={na} FAIL={failed} (total {len(summary)})") + + if failures: + print(f"\n{'=' * 70}\nFAILURE DETAILS\n{'=' * 70}") + for source, fn_name, tb in failures: + print(f"\n----- {source} :: {fn_name} -----\n{tb}") + sys.exit(1) + + print("\nAll assigned analytical functions ran successfully on every source.") + + +if __name__ == "__main__": + main() diff --git a/www/services/__init__.py b/www/services/__init__.py index 28584e105..8bce11921 100644 --- a/www/services/__init__.py +++ b/www/services/__init__.py @@ -14,4 +14,8 @@ from .tabletag import * from .termextraction import * from .thematicmap import * -from .utils import * \ No newline at end of file +from .utils import * +from .etl_pipeline import * +from .column_mappings import * +from .validator import * +from .api_retriever import * \ No newline at end of file diff --git a/www/services/api_retriever.py b/www/services/api_retriever.py new file mode 100644 index 000000000..5f0c9a8de --- /dev/null +++ b/www/services/api_retriever.py @@ -0,0 +1,376 @@ +""" +Live API retrievers for the Bibliometrix ETL pipeline. + +This module exposes :class:`APIRetriever`, a thin client that queries two +external bibliographic databases and returns results as ``pandas.DataFrame`` +in the *raw* per-source format expected by the ETL pipeline (which then +normalises them through :mod:`column_mappings`): + +- **OpenAlex** (``https://api.openalex.org``) — paginated REST API + returning JSON. We reconstruct the inverted-index abstract, flatten + authors/affiliations/biblio, and stream pages with an exponential-backoff + retry budget on 429 and 5xx. +- **PubMed** (NCBI E-utilities ESearch + EFetch) — returns plain-text + MEDLINE format which we delegate to :func:`parsers.parse_pubmed_data` + via a temporary file. +""" + +import os +import re +import time +import logging +import tempfile +import requests +import pandas as pd +from typing import List, Dict, Any, Optional + +from .parsers import parse_pubmed_data + +logger = logging.getLogger(__name__) + +class APIRetriever: + """ + API client for OpenAlex and PubMed to dynamically retrieve bibliographic data. + + The retriever is stateless apart from an identifying email address + (recommended by both OpenAlex and the NCBI E-utilities for the + *polite pool*). All HTTP calls are made with a descriptive + ``User-Agent`` header to ease debugging if a request is rate-limited. + + Attributes: + email: Contact email forwarded as ``mailto=`` to OpenAlex and in + the User-Agent header. + headers: HTTP headers reused across every request issued by the + instance. + """ + def __init__(self, email: str = "user@example.com") -> None: + """ + Build a retriever identified by ``email``. + + Args: + email: Contact address used by OpenAlex/PubMed to route us + into the *polite pool* (higher rate-limit budget). A + placeholder is used if the caller does not set one. + """ + self.email: str = email + self.headers: Dict[str, str] = { + "User-Agent": f"BibliometrixPythonETL/1.0 (mailto:{self.email})" + } + + def _reconstruct_openalex_abstract(self, inverted_index: Optional[Dict[str, List[int]]]) -> str: + """ + Reassemble a textual abstract from OpenAlex's ``abstract_inverted_index``. + + OpenAlex distributes abstracts as a mapping + ``{word: [position1, position2, ...]}`` instead of plain text + (it sidesteps publisher copyright on the literal abstract). We + invert that mapping back into a single string, ordered by + position. + + Args: + inverted_index: The raw ``abstract_inverted_index`` payload + returned by OpenAlex, or ``None`` when no abstract is + available. + + Returns: + The reconstructed abstract as a space-separated string, or + an empty string when the input is missing/malformed or any + unexpected error occurs during reconstruction. + """ + if not inverted_index or not isinstance(inverted_index, dict): + return "" + try: + word_positions = [] + for word, positions in inverted_index.items(): + for pos in positions: + word_positions.append((pos, word)) + word_positions.sort() + return " ".join([word for pos, word in word_positions]) + except Exception: + return "" + + def query_openalex(self, query: str, max_results: int = 100) -> pd.DataFrame: + """ + Query the OpenAlex ``/works`` endpoint and return raw bibliographic rows. + + Pages are streamed 100 rows at a time (the API maximum per page). + For each work we extract a flat row whose columns mirror the keys + expected by ``COLUMN_MAPPINGS["openalex"]``: ``id``, ``title``, + ``abstract``, ``publication_year``, ``doi``, ``type``, + ``cited_by_count``, ``authors``, ``author_full_names``, + ``affiliations``, ``journal``, ``keywords``, ``references``, + ``volume``, ``issue``, ``first_page``, ``last_page``, ``pmid``. + + Multi-value fields (authors, affiliations, references, keywords) + are joined with ``"; "`` so they round-trip as strings; the ETL + layer is responsible for splitting them back into lists. + + Reliability: + - HTTP 429 (rate-limited) and 5xx are retried with exponential + backoff (1, 2, 4, 8, 16 s capped at 30 s). + - Up to ``MAX_RETRIES_PER_PAGE = 5`` consecutive transient + failures are tolerated per page; afterwards the loop exits + gracefully and we return whatever rows we already collected. + - Network-level :class:`requests.exceptions.RequestException` + is handled by the same retry budget. + - Any other exception (e.g. JSON decode error) ends the loop + without dropping already-fetched rows. + + Args: + query: Free-text search string (the same string accepted by + the OpenAlex web UI). + max_results: Maximum number of rows to return. Pagination + stops once this limit is reached; ``100`` is the default + soft cap. + + Returns: + ``pandas.DataFrame`` with one row per work. Empty DataFrame + if no results were found. + """ + url = "https://api.openalex.org/works" + params = { + "search": query, + "per_page": min(max_results, 100), + "page": 1 + } + if self.email: + params["mailto"] = self.email + + results = [] + fetched = 0 + # Retry budget per page: how many consecutive transient failures + # (429, 5xx, timeouts) we tolerate before giving up on that page. + MAX_RETRIES_PER_PAGE = 5 + retries = 0 + + while fetched < max_results: + try: + response = requests.get(url, params=params, headers=self.headers, timeout=15) + + # Transient: rate limited. Back off with exponential delay, + # capped by the retry budget so we never loop forever. + if response.status_code == 429: + if retries >= MAX_RETRIES_PER_PAGE: + logger.warning( + "OpenAlex: rate-limit retry budget exhausted on page %s; stopping with %d results.", + params['page'], fetched, + ) + break + sleep_s = min(2 ** retries, 30) + retries += 1 + time.sleep(sleep_s) + continue + + # Transient: server error. Retry the same page within budget. + if 500 <= response.status_code < 600: + if retries >= MAX_RETRIES_PER_PAGE: + logger.warning( + "OpenAlex: 5xx retry budget exhausted on page %s; stopping with %d results.", + params['page'], fetched, + ) + break + sleep_s = min(2 ** retries, 30) + retries += 1 + time.sleep(sleep_s) + continue + + response.raise_for_status() + # Successful response → reset the retry counter for the next page. + retries = 0 + data = response.json() + + works = data.get("results", []) + if not works: + break + + for work in works: + # Extract authors (full names and initials) + authors_list = [] + authors_full = [] + affiliations_list = [] + + for auth in work.get("authorships", []): + display_name = auth.get("author", {}).get("display_name", "") + if display_name: + authors_full.append(display_name) + # Format to initials: Surname I. + parts = display_name.split() + if len(parts) > 1: + surname = parts[-1] + initials = "".join([p[0] + "." for p in parts[:-1]]) + authors_list.append(f"{surname} {initials}") + else: + authors_list.append(display_name) + + # Affiliations + for inst in auth.get("institutions", []): + inst_name = inst.get("display_name", "") + if inst_name and inst_name not in affiliations_list: + affiliations_list.append(inst_name) + + # Extract publication venue + journal_name = "" + volume = "" + issue = "" + first_page = "" + last_page = "" + + loc = work.get("primary_location", {}) or {} + source = loc.get("source", {}) or {} + journal_name = source.get("display_name", "") or "" + + biblio = work.get("biblio", {}) or {} + volume = biblio.get("volume", "") or "" + issue = biblio.get("issue", "") or "" + first_page = biblio.get("first_page", "") or "" + last_page = biblio.get("last_page", "") or "" + + # Keywords from concepts + concepts = work.get("concepts", []) or [] + keywords = [c.get("display_name", "") for c in concepts if c.get("display_name")] + + # Extract PMID and DOI + ids = work.get("ids", {}) or {} + pmid = ids.get("pmid", "") + if pmid: + pmid = str(pmid).replace("https://pubmed.ncbi.nlm.nih.gov/", "") + + doi = work.get("doi", "") + if doi: + doi = str(doi).replace("https://doi.org/", "") + + # Cited references list + referenced_works = work.get("referenced_works", []) or [] + + work_flat = { + "id": work.get("id", ""), + "title": work.get("title", ""), + "abstract": self._reconstruct_openalex_abstract(work.get("abstract_inverted_index")), + "publication_year": str(work.get("publication_year", "")), + "doi": doi, + "type": work.get("type", ""), + "cited_by_count": work.get("cited_by_count", 0), + "authors": "; ".join(authors_list), + "author_full_names": "; ".join(authors_full), + "affiliations": "; ".join(affiliations_list), + "journal": journal_name, + "keywords": "; ".join(keywords), + "references": "; ".join(referenced_works), + "volume": str(volume), + "issue": str(issue), + "first_page": str(first_page), + "last_page": str(last_page), + "pmid": pmid, + } + results.append(work_flat) + fetched += 1 + if fetched >= max_results: + break + + params["page"] += 1 + # Respect rate limits politely + time.sleep(0.2) + + except requests.exceptions.RequestException as e: + # Network-level transient error (timeout, connection reset). + # Retry within the same budget so we don't drop already-fetched rows. + if retries >= MAX_RETRIES_PER_PAGE: + logger.warning( + "OpenAlex: network retry budget exhausted (%s); stopping with %d results.", + e, fetched, + ) + break + sleep_s = min(2 ** retries, 30) + retries += 1 + time.sleep(sleep_s) + continue + except Exception: + # Non-transient (e.g. JSON decode error on a malformed page). + # Stop the loop but keep whatever results we have collected. + logger.exception("Error querying OpenAlex API") + break + + return pd.DataFrame(results) + + def query_pubmed(self, query: str, max_results: int = 100) -> pd.DataFrame: + """ + Query PubMed via NCBI E-utilities and return one row per article. + + The retrieval is a two-step process: + + 1. **ESearch** — translate the textual ``query`` into a list of + PMIDs (up to ``max_results``). + 2. **EFetch** — download the matching records in plain-text + MEDLINE format. The MEDLINE blob is then written to a + system-temp file and parsed by + :func:`parsers.parse_pubmed_data`, which already knows how to + normalise PubMed records into the dashboard schema. + + The temp file uses :func:`tempfile.mkstemp` (CWD-independent and + race-free across concurrent users) and is deleted in a + ``finally`` block so we never leave artefacts on disk. + + Args: + query: Free-text PubMed query (the same syntax as + ``https://pubmed.ncbi.nlm.nih.gov``). + max_results: Cap on the number of PMIDs to fetch. Defaults + to ``100``. + + Returns: + ``pandas.DataFrame`` with PubMed records, or an empty + DataFrame if ESearch/EFetch fail or no articles match. + """ + esearch_url = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi" + efetch_url = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi" + + # 1. ESearch to retrieve IDs + search_params = { + "db": "pubmed", + "term": query, + "retmode": "json", + "retmax": max_results + } + + try: + response = requests.get(esearch_url, params=search_params, headers=self.headers, timeout=15) + response.raise_for_status() + search_data = response.json() + id_list = search_data.get("esearchresult", {}).get("idlist", []) + except Exception: + logger.exception("Error searching PubMed") + return pd.DataFrame() + + if not id_list: + logger.warning("No articles found on PubMed for the query: %r", query) + return pd.DataFrame() + + # 2. EFetch to retrieve MEDLINE text for the IDs + fetch_params = { + "db": "pubmed", + "id": ",".join(id_list), + "retmode": "text", + "rettype": "medline" + } + + try: + fetch_response = requests.post(efetch_url, data=fetch_params, headers=self.headers, timeout=20) + fetch_response.raise_for_status() + medline_text = fetch_response.text + except Exception: + logger.exception("Error fetching MEDLINE data from PubMed") + return pd.DataFrame() + + # 3. Save the MEDLINE text to a *system* temporary file so that + # concurrent API queries cannot race on the same path and so that + # the file lives in a CWD-independent location. + fd, temp_file_path = tempfile.mkstemp(suffix=".txt", prefix="pubmed_api_") + try: + with os.fdopen(fd, "w", encoding="utf-8") as f: + f.write(medline_text) + parsed_records = parse_pubmed_data(temp_file_path) + finally: + if os.path.exists(temp_file_path): + os.remove(temp_file_path) + + # Convert list of dicts to DataFrame + return pd.DataFrame(parsed_records) diff --git a/www/services/biblionetwork.py b/www/services/biblionetwork.py index 7e65b4880..723bf3e11 100644 --- a/www/services/biblionetwork.py +++ b/www/services/biblionetwork.py @@ -5,6 +5,18 @@ def biblionetwork(M, analysis="coupling", network="authors", n=None, sep=";", short=False, shortlabel=True, remove_terms=None, synonyms=None): def crossprod(A, B): + # Guard against an empty field: cocMatrix returns None when the + # requested field (e.g. CR cited references) is absent/empty in the + # dataset. Raise a clear, user-facing message instead of letting the + # cryptic "'NoneType' object has no attribute 'T'" bubble up. The + # dashboard's try/except shows this text to the user. + if A is None or B is None: + raise ValueError( + "This analysis requires data that is not present in the loaded dataset " + f"(the '{network}' field is empty). For example, PubMed and Dimensions " + "exports usually do not include the cited-references list needed for " + "co-citation/coupling networks." + ) return A.T @ B # Moltiplicazione matriciale per ottenere il prodotto incrociato NetMatrix = None @@ -16,7 +28,9 @@ def crossprod(A, B): CRA = crossprod(WCR, WA) NetMatrix = crossprod(CRA, CRA) elif network == "references": - WCR = cocMatrix(M, Field="CR", type="sparse", n=n, sep=sep, short=short).T + WCR = cocMatrix(M, Field="CR", type="sparse", n=n, sep=sep, short=short) + # Transpose only if present; crossprod() raises a clear message if None. + WCR = WCR.T if WCR is not None else None NetMatrix = crossprod(WCR, WCR) elif network == "sources": WSO = cocMatrix(M, Field="SO", type="sparse", n=n, sep=sep, short=short) diff --git a/www/services/column_mappings.py b/www/services/column_mappings.py new file mode 100644 index 000000000..9c3629f57 --- /dev/null +++ b/www/services/column_mappings.py @@ -0,0 +1,176 @@ +""" +Centralised column-rename tables that map every supported source schema +onto the canonical Web of Science (WoS) tag set used by the dashboard. + +Each top-level key in :data:`COLUMN_MAPPINGS` is the lower-case name of +a supported database (``"scopus"``, ``"pubmed"``, ``"openalex"``, …) and +each inner mapping has the shape ``{source_column_name: wos_tag}``. The +ETL pipeline (see :func:`etl_pipeline.BibliometrixETL.run`) selects the +mapping from this dict by the user-supplied ``database`` argument and +then renames columns in a single ``df.rename(columns=...)`` pass. + +Canonical WoS tags used as targets include: + +- Identifiers: ``UT``, ``DI``, ``PMID``, ``SN`` +- Content: ``TI``, ``AB``, ``DE`` (author keywords), ``ID`` (index keywords) +- Authorship: ``AU`` (surname), ``AF`` (full names), ``C1`` (affiliations), + ``RP`` (reprint address) +- Venue: ``SO`` (source title), ``JI`` (abbreviated journal), ``PY`` (year), + ``VL`` (volume), ``IS`` (issue), ``BP`` (begin page), ``EP`` (end page) +- Bibliometrics: ``TC`` (times cited), ``CR`` (cited references), ``DT`` + (document type), ``LA`` (language), ``PU`` (publisher), ``FU``/``FX`` + (funding) +- Special tokens used by post-processing: ``"Pagination"`` is a *temporary* + placeholder for sources (Dimensions, PubMed) where ``BP`` and ``EP`` + are merged into a single column and must be split downstream. + +Adding support for a new source therefore reduces to appending a new +sub-dictionary here — no other module needs to be changed. +""" + +from typing import Dict + +COLUMN_MAPPINGS: Dict[str, Dict[str, str]] = { + 'web_of_science': { + 'AB': 'AB', + 'AF': 'AF', + 'AU': 'AU', + 'BP': 'BP', + 'C1': 'C1', + 'CR': 'CR', + 'DE': 'DE', + 'DI': 'DI', + 'DT': 'DT', + 'EM': 'EM', + 'EP': 'EP', + 'FU': 'FU', + 'FX': 'FX', + 'ID': 'ID', + 'IS': 'IS', + 'JI': 'JI', + 'LA': 'LA', + 'PM': 'PMID', + 'PY': 'PY', + 'RP': 'RP', + 'SN': 'SN', + 'SO': 'SO', + 'TC': 'TC', + 'TI': 'TI', + 'UT': 'UT', + 'VL': 'VL', + }, + 'scopus': { + 'Abstract': 'AB', + 'Author full names': 'AF', + 'Authors': 'AU', + 'References': 'CR', + 'Affiliations': 'C1', + 'Author Keywords': 'DE', + 'Index Keywords': 'ID', + 'DOI': 'DI', + 'Document Type': 'DT', + 'Correspondence Address': 'RP', + 'Source title': 'SO', + 'Year': 'PY', + 'Cited by': 'TC', + 'Title': 'TI', + 'EID': 'UT', + 'Volume': 'VL', + 'Issue': 'IS', + 'Page start': 'BP', + 'Page end': 'EP', + 'PubMed ID': 'PMID', + 'Publisher': 'PU', + 'ISSN': 'SN', + 'Language of Original Document': 'LA', + }, + 'dimensions': { + 'Abstract': 'AB', + 'Authors': 'AU', + 'Authors (Raw Affiliation)': 'C1', # Requires regex/special extraction + 'MeSH terms': 'DE', + 'DOI': 'DI', + 'PubYear': 'PY', + 'Publication Type': 'DT', + 'Corresponding Authors': 'RP', + 'Source title': 'SO', + 'Times cited': 'TC', + 'Title': 'TI', + 'Publication ID': 'UT', + 'Volume': 'VL', + 'Issue': 'IS', + 'Pagination': 'Pagination', # Requires splitting into BP and EP + 'PMID': 'PMID', + 'Funding': 'FU', + 'Acknowledgements': 'FX', + }, + 'lens': { + 'Abstract': 'AB', + 'Author/s': 'AU', + 'Keywords': 'DE', + 'DOI': 'DI', + 'Publication Type': 'DT', + 'Publication Year': 'PY', + 'Source Title': 'SO', + 'Citing Works Count': 'TC', + 'Title': 'TI', + 'Lens ID': 'UT', + 'Volume': 'VL', + 'Issue': 'IS', + 'Start Page': 'BP', + 'End Page': 'EP', + 'PMID': 'PMID', + 'Funding': 'FU', + 'ISSNs': 'SN', + 'Open Access Colour': 'OA', + }, + 'pubmed': { + 'AB': 'AB', + 'FAU': 'AF', + 'AU': 'AU', + 'AD': 'C1', + 'MH': 'DE', + 'LID': 'DI', + 'PT': 'DT', + 'JT': 'SO', + 'DP': 'PY', + 'TI': 'TI', + 'PMID': 'UT', + 'VI': 'VL', + 'IP': 'IS', + 'PG': 'Pagination', + 'GR': 'FU', + 'TA': 'JI', + }, + 'cochrane': { + 'AB': 'AB', + 'AU': 'AU', + 'KY': 'DE', + 'DOI': 'DI', + 'SO': 'SO', + 'YR': 'PY', + 'TI': 'TI', + 'ID': 'UT', + 'SN': 'SN', + }, + 'openalex': { + 'id': 'UT', + 'title': 'TI', + 'abstract': 'AB', + 'publication_year': 'PY', + 'doi': 'DI', + 'type': 'DT', + 'cited_by_count': 'TC', + 'authors': 'AU', + 'author_full_names': 'AF', + 'affiliations': 'C1', + 'journal': 'SO', + 'keywords': 'DE', + 'references': 'CR', + 'volume': 'VL', + 'issue': 'IS', + 'first_page': 'BP', + 'last_page': 'EP', + 'pmid': 'PMID', + } +} diff --git a/www/services/etl_pipeline.py b/www/services/etl_pipeline.py new file mode 100644 index 000000000..733d44092 --- /dev/null +++ b/www/services/etl_pipeline.py @@ -0,0 +1,788 @@ +""" +Source-agnostic ETL pipeline for the Bibliometrix dashboard. + +This is the *core* module of the project. It accepts bibliographic +records from any of seven supported databases — Web of Science, Scopus, +Dimensions, Lens, PubMed, Cochrane, OpenAlex — and emits a single +DataFrame that conforms to the canonical Web of Science schema expected +by the rest of the dashboard. After the user picks a database in the +UI, every subsequent visualisation tab reads the *same* normalised +DataFrame: the visualisation code is decoupled from the original source +format. + +The pipeline is organised in five named phases: + +1. **Extract** (:meth:`BibliometrixETL.extract`) — load the raw file + from disk and turn it into a DataFrame. Each source has its own + parser (CSV via :func:`_read_csv_safe`, Excel via + :func:`pandas.read_excel`, plain text via :mod:`parsers`, BibTeX via + :class:`bibtexparser.bparser.BibTexParser`). +2. **Transform** (:meth:`BibliometrixETL.transform`) — rename columns + per :data:`column_mappings.COLUMN_MAPPINGS`, split merged ``Pagination`` + fields, compute the *Short Reference* (``SR``) tag, resolve duplicate + columns produced by aliased mappings, apply type contracts, and + convert multi-value columns into ``list[str]``. +3. **Validate** (:meth:`BibliometrixETL.validate`) — delegate to + :func:`validator.validate_dataframe` which fails fast if the schema + contract is violated. +4. **Run** (:meth:`BibliometrixETL.run`) — orchestrate phases 1-3 for + a file-based input. +5. **Run via API** (:meth:`BibliometrixETL.run_api`) — same as + :meth:`run` but the Extract phase is replaced by a live call to + :class:`api_retriever.APIRetriever`. + +Defensive helpers (:func:`is_null`, :func:`_read_csv_safe`, +:func:`_open_text_safe`) are kept at module level so they can be +unit-tested independently of the orchestrator class. +""" + +import os +import re +import io +import logging +import pandas as pd +import numpy as np +from typing import Union, List, Dict, Any + +# Import local modules +from .parsers import parse_wos_data, parse_pubmed_data, parse_cochrane_data +from .column_mappings import COLUMN_MAPPINGS +from .validator import validate_dataframe, MANDATORY_COLUMNS, MULTIVALUE_COLUMNS +from .api_retriever import APIRetriever + +logger = logging.getLogger(__name__) + +# Attempt to import bibtexparser (should be installed via requirements.txt) +try: + from bibtexparser.bparser import BibTexParser +except ImportError: + BibTexParser = None + + +def is_null(val: Any) -> bool: + """ + Container-safe null check used throughout the ETL. + + The standard :func:`pandas.isna` raises ``ValueError`` (or returns + a boolean array) when called on a list, tuple, ``ndarray`` or + ``Series``. The ETL frequently inspects heterogeneous cells (a + column may contain a mix of strings, ``NaN``, and Python lists + produced by previous transform steps), so we wrap :func:`pd.isna` + with explicit handling for containers. + + Containers are *never* considered null even when empty: an empty + list still represents a structurally valid (albeit value-less) + multi-value cell, and the downstream validator distinguishes + "missing column" from "empty list" intentionally. + + Args: + val: Any value, scalar or container. + + Returns: + ``True`` if ``val`` is :data:`None` or a scalar NaN. + ``False`` for containers (``list``, ``tuple``, ``dict``, + ``set``, ``numpy.ndarray``, ``pandas.Series``) and for any + non-null scalar. + """ + if val is None: + return True + if isinstance(val, (list, tuple, dict, set, np.ndarray, pd.Series)): + return False + return pd.isna(val) + + +# Encodings tried in order when a source file is not valid UTF-8. latin-1 +# is kept last because it cannot fail (it maps every byte to a codepoint), +# so it acts as the universal fallback. +_ENCODING_FALLBACKS = ("utf-8", "utf-8-sig", "cp1252", "latin-1") + +# Placeholder tokens (case-insensitive) that legacy exports use in place +# of a real missing value. We treat them as null during cleaning so that +# the validator's type contracts see uniform "" / [] / 0 rather than the +# literal strings "nan" / "null" / "none". A frozenset is used for O(1) +# membership lookup; the contents are matched against `.strip().lower()`. +_NULL_STRINGS = frozenset({"nan", "null", "none", ""}) + + +def _read_csv_safe(path: str, **kwargs: Any) -> pd.DataFrame: + """ + :func:`pandas.read_csv` wrapper with an encoding fallback chain. + + Reads ``path`` trying each encoding in :data:`_ENCODING_FALLBACKS` + in order. Real-world exports are unfortunately not always UTF-8: + + - Scopus and Dimensions exports created on Windows locales are + typically ``cp1252``. + - Legacy PubMed dumps occasionally ship as ``latin-1``. + + ``latin-1`` is positioned last because it physically cannot fail + (every byte maps to a valid codepoint), so by the time we reach it + the function is guaranteed to return. + + Args: + path: Filesystem path to the CSV file. + **kwargs: Forwarded verbatim to :func:`pandas.read_csv` + (e.g. ``skiprows``, ``sep``, ``dtype``). + + Returns: + The parsed :class:`pandas.DataFrame`. + + Raises: + UnicodeDecodeError: Only if every encoding in the fallback + chain rejects the file, which in practice cannot happen + because ``latin-1`` accepts arbitrary byte sequences. + """ + last_exc = None + for enc in _ENCODING_FALLBACKS: + try: + return pd.read_csv(path, encoding=enc, **kwargs) + except UnicodeDecodeError as exc: + last_exc = exc + continue + raise last_exc if last_exc else UnicodeDecodeError("utf-8", b"", 0, 0, "unknown") + + +def _open_text_safe(path: str) -> str: + """ + Read a text file as a single string, trying multiple encodings. + + Mirrors :func:`_read_csv_safe` but for the plain-text parsers + (WoS, PubMed, Cochrane, BibTeX). Returns the decoded file content; + same fallback rationale as :func:`_read_csv_safe`. + + Args: + path: Filesystem path to a text file. + + Returns: + The decoded file content. + + Raises: + UnicodeDecodeError: Only if every encoding in the fallback + chain rejects the file (effectively unreachable thanks to + the ``latin-1`` fallback). + """ + last_exc = None + for enc in _ENCODING_FALLBACKS: + try: + with open(path, "r", encoding=enc) as f: + return f.read() + except UnicodeDecodeError as exc: + last_exc = exc + continue + raise last_exc if last_exc else UnicodeDecodeError("utf-8", b"", 0, 0, "unknown") + + +class BibliometrixETL: + """ + Orchestrator for the source-agnostic bibliographic ETL pipeline. + + Mirrors the role played by R's ``convert2df`` in the original + ``bibliometrix`` package: it exposes a single entry point + (:meth:`run` for files, :meth:`run_api` for live queries) and + sequences the Extract → Transform → Validate phases internally. + + The class is intentionally lightweight — it holds only a reference + to :data:`column_mappings.COLUMN_MAPPINGS` and is safe to + instantiate per-request from the Shiny server function. + + Attributes: + mappings: Reference to :data:`COLUMN_MAPPINGS`; held as an + instance attribute so subclasses or tests can inject a + custom mapping table without monkey-patching the module. + """ + def __init__(self) -> None: + """Initialise the orchestrator with the default column mappings.""" + self.mappings: Dict[str, Dict[str, str]] = COLUMN_MAPPINGS + + def extract(self, data_path: str, source_db: str, file_type: str) -> pd.DataFrame: + """ + Phase 1 — load raw bibliographic data from disk into a DataFrame. + + Dispatches to the appropriate parser based on + ``(source_db, file_type)``: + + ============ ===================== =========================== + Source Supported file types Parser + ============ ===================== =========================== + WoS ``.txt``, ``.ciw`` :func:`parsers.parse_wos_data` + WoS ``.bib`` :class:`BibTexParser` + Scopus ``.csv`` :func:`_read_csv_safe` + Scopus ``.bib`` :class:`BibTexParser` + Dimensions ``.xlsx`` :func:`pandas.read_excel` + Dimensions ``.csv`` :func:`_read_csv_safe` (skiprows=1) + Lens ``.csv`` :func:`_read_csv_safe` + PubMed ``.txt`` :func:`parsers.parse_pubmed_data` + Cochrane ``.txt`` :func:`parsers.parse_cochrane_data` + ============ ===================== =========================== + + Column names of the returned DataFrame are stripped of + whitespace as a basic cleanup; no other normalisation happens + in this phase. + + Args: + data_path: Absolute path to the source file. + source_db: Source database identifier. Case-insensitive; + aliases ``"wos"`` and ``"the_lens"`` are accepted in + addition to the canonical ``"web_of_science"`` / + ``"lens"``. + file_type: File extension, with or without the leading + dot. + + Returns: + A *raw* :class:`pandas.DataFrame` whose columns still use + the source's native field names. Normalisation happens in + :meth:`transform`. + + Raises: + FileNotFoundError: If ``data_path`` does not exist. + ValueError: If the database/file-type combination is not + supported, or if the parsed DataFrame is empty. + ImportError: If a ``.bib`` file is requested but + ``bibtexparser`` is not installed. + """ + source_db_key = source_db.lower().strip() + # Normalise key names to match COLUMN_MAPPINGS keys + if source_db_key == "wos": + source_db_key = "web_of_science" + elif source_db_key == "lens": + source_db_key = "lens" + + file_type = file_type.lower().strip() + if not file_type.startswith('.'): + file_type = '.' + file_type + + # Check file existence + if not os.path.exists(data_path): + raise FileNotFoundError(f"Source file not found: {data_path}") + + raw_entries: List[Dict[str, Any]] = [] + df_raw: pd.DataFrame = pd.DataFrame() + + # Web of Science (wos) + if source_db_key == "web_of_science": + if file_type == ".bib": + if BibTexParser is None: + raise ImportError("bibtexparser is not installed. Please install it to parse .bib files.") + bib_parser = BibTexParser() + bib_text = _open_text_safe(data_path) + bib_data = bib_parser.parse(bib_text) + raw_entries = bib_data.entries + df_raw = pd.DataFrame(raw_entries) + elif file_type in (".txt", ".ciw"): + raw_entries = parse_wos_data(data_path) + df_raw = pd.DataFrame(raw_entries) + else: + raise ValueError( + f"Unsupported file type '{file_type}' for Web of Science. " + f"Accepted formats: .txt / .ciw (plain-text export) or .bib (BibTeX)." + ) + + # Scopus + elif source_db_key == "scopus": + if file_type == ".bib": + if BibTexParser is None: + raise ImportError("bibtexparser is not installed. Please install it to parse .bib files.") + bib_parser = BibTexParser() + bib_text = _open_text_safe(data_path) + bib_data = bib_parser.parse(bib_text) + raw_entries = bib_data.entries + df_raw = pd.DataFrame(raw_entries) + elif file_type == ".csv": + df_raw = _read_csv_safe(data_path) + else: + raise ValueError( + f"Unsupported file type '{file_type}' for Scopus. " + f"Accepted formats: .csv or .bib (BibTeX)." + ) + + # Dimensions + elif source_db_key == "dimensions": + if file_type == ".xlsx": + df_raw = pd.read_excel(data_path, skiprows=1) + elif file_type == ".csv": + df_raw = _read_csv_safe(data_path, skiprows=1) + else: + raise ValueError( + f"Unsupported file type '{file_type}' for Dimensions. " + f"Accepted formats: .xlsx or .csv." + ) + + # Lens.org + elif source_db_key in ("lens", "the_lens"): + if file_type == ".csv": + df_raw = _read_csv_safe(data_path) + else: + raise ValueError( + f"Unsupported file type '{file_type}' for Lens.org. " + f"Accepted format: .csv." + ) + + # PubMed + elif source_db_key == "pubmed": + if file_type == ".txt": + raw_entries = parse_pubmed_data(data_path) + df_raw = pd.DataFrame(raw_entries) + else: + raise ValueError( + f"Unsupported file type '{file_type}' for PubMed. " + f"PubMed exports must be MEDLINE/PubMed-format .txt files " + f"(there is no PubMed .csv export) — make sure the selected " + f"database matches the file you uploaded." + ) + + # Cochrane + elif source_db_key == "cochrane": + if file_type == ".txt": + raw_entries = parse_cochrane_data(data_path) + df_raw = pd.DataFrame(raw_entries) + else: + raise ValueError( + f"Unsupported file type '{file_type}' for Cochrane Library. " + f"Accepted format: .txt (Cochrane plain-text export)." + ) + + else: + raise ValueError(f"Unknown database source '{source_db}'") + + if df_raw.empty: + raise ValueError(f"Extracted data is empty for file: {data_path}") + + # Basic cleanup: strip column names + df_raw.columns = [str(col).strip() for col in df_raw.columns] + return df_raw + + def transform(self, df_raw: pd.DataFrame, source_db: str, file_type: str, author_format: str = "surname") -> pd.DataFrame: + """ + Phases 2-3 — normalise the raw DataFrame into the canonical WoS schema. + + Executed in this order: + + 1. **Pre-processing.** Dimensions-specific extraction of + ``C1`` (affiliations) from the raw authors string; split of + merged ``Pagination`` fields into ``BP`` / ``EP`` for + Dimensions and PubMed. + 2. **SR computation.** A *Short Reference* (``SR``) is built + for every row by calling + :func:`format_functions.format_sr_column`. Missing fields + are coerced to empty strings before the call to avoid + ``AttributeError`` on float-NaN cells. + 3. **Column renaming.** A single + :meth:`pandas.DataFrame.rename` call applies the + source-specific mapping from :data:`COLUMN_MAPPINGS`. + 4. **Duplicate-column resolution.** If two source columns + rename to the same WoS tag, multi-value columns are + merged element-wise and scalar columns take the first + non-null, non-placeholder value. + 5. **Column presence.** Any mandatory WoS tag still missing + is initialised with ``""`` (scalar) or ``[]`` (multi-value). + 6. **Type contracts.** Scalar columns are coerced to stripped + strings; ``PY`` to a 4-digit year string; ``TC`` to an + integer (defaulting to 0); multi-value columns to + ``list[str]`` using a source-dependent delimiter. + 7. **Author format.** Drops the column not selected by + ``author_format`` and trims the schema down to exactly the + mandatory columns. + + Args: + df_raw: DataFrame returned by :meth:`extract`. + source_db: Same identifier passed to :meth:`extract`. + file_type: Same identifier passed to :meth:`extract`. + author_format: ``"surname"`` keeps ``AU`` and drops + ``AF``; ``"fullname"`` does the opposite. Defaults to + ``"surname"``. + + Returns: + A schema-compliant :class:`pandas.DataFrame` ready for + :meth:`validate`. + + Raises: + ValueError: If no column mapping exists for ``source_db``. + """ + # 1. Normalise database source name + source_db_key = source_db.lower().strip() + if source_db_key == "wos": + source_db_key = "web_of_science" + elif source_db_key == "lens": + source_db_key = "lens" + + mapping = self.mappings.get(source_db_key, {}) + if not mapping: + raise ValueError(f"No column mappings found for database source: {source_db}") + + df = df_raw.copy() + + # 2. Database-specific pre-processing before column renaming + # Extract C1 (Affiliations) for Dimensions from raw authors string if applicable + if source_db_key == "dimensions" and "Authors (Raw Affiliation)" in df.columns: + # Save Raw Affiliation extraction so we can map it to C1 + df["C1_extracted"] = df["Authors (Raw Affiliation)"].apply( + lambda val: "; ".join(re.findall(r'\((.*?)\)', str(val))) if pd.notna(val) else "" + ) + # Override mapping for dimensions C1 to map to our extracted helper column + mapping = mapping.copy() + if "Authors (Raw Affiliation)" in mapping: + del mapping["Authors (Raw Affiliation)"] + mapping["C1_extracted"] = "C1" + + # Split Pagination into BP and EP for Dimensions and PubMed if present + if "Pagination" in mapping and mapping["Pagination"] in df.columns: + pag_col = mapping["Pagination"] + def get_bp(val: Any) -> str: + """Return the begin-page portion of a ``"123-456"`` pagination string.""" + if is_null(val): return "" + if isinstance(val, (list, tuple, np.ndarray, pd.Series)): + val = val[0] if len(val) > 0 else "" + parts = re.split(r'[-–—]', str(val)) + return parts[0].strip() if len(parts) > 0 else "" + def get_ep(val: Any) -> str: + """Return the end-page portion of a ``"123-456"`` pagination string.""" + if is_null(val): return "" + if isinstance(val, (list, tuple, np.ndarray, pd.Series)): + val = val[0] if len(val) > 0 else "" + parts = re.split(r'[-–—]', str(val)) + return parts[1].strip() if len(parts) > 1 else "" + + df["BP"] = df[pag_col].apply(get_bp) + df["EP"] = df[pag_col].apply(get_ep) + + # 3. Calculate Short Reference (SR) using the codebase's existing function format_sr_column + # To call format_sr_column, we must pass the row as a dictionary, the source, and file_type. + # But format_sr_column expects source name formatted as in format_functions (e.g. 'Web_of_Science', 'Scopus' etc.) + source_db_fmt = { + "web_of_science": "Web_of_Science", + "scopus": "Scopus", + "dimensions": "Dimensions", + "lens": "The_Lens", + "pubmed": "PubMed", + "cochrane": "Cochrane" + }.get(source_db_key, source_db) + + # Ensure correct file type format for format_sr_column (starts with .) + ft = file_type.lower().strip() + if not ft.startswith('.'): + ft = '.' + ft + + def compute_sr_row(row: pd.Series) -> str: + """ + Compute the Short Reference (``SR``) for a single DataFrame row. + + Delegates the heavy lifting to + :func:`format_functions.format_sr_column` but sanitises the + row first: NaN/None values are coerced to ``""`` because + ``format_sr_column`` calls ``.split()`` on its inputs and + would otherwise crash on float-NaN cells (common in + PubMed/Dimensions when the author or journal is missing). + Any unexpected error is swallowed with a warning so that + SR computation can never abort the whole pipeline. + """ + try: + from .format_functions import format_sr_column + row_dict = { + k: ("" if (v is None or (isinstance(v, float) and pd.isna(v))) else v) + for k, v in row.to_dict().items() + } + return format_sr_column(row_dict, source_db_fmt, ft) + except Exception: + # Last-resort fallback: never let SR computation crash the pipeline. + logger.warning("format_sr_column failed for row", exc_info=True) + return "" + + df["SR"] = df.apply(compute_sr_row, axis=1) + + # 4. Rename columns according to mapping + df = df.rename(columns=mapping) + + # Resolve duplicate columns if any exist + if df.columns.duplicated().any(): + dup_cols = df.columns[df.columns.duplicated()].unique() + for col in dup_cols: + col_df = df[col] + if isinstance(col_df, pd.DataFrame): + # Combine columns row-wise + if col in MULTIVALUE_COLUMNS: + def merge_rows(row: pd.Series) -> List[str]: + """ + Merge duplicate multi-value columns into a single ``list[str]``. + + Iterates the duplicate-column slice of one row, + flattening any container values and splitting + semicolon-joined strings; null/empty/``"nan"`` + placeholders are dropped. + """ + merged = [] + for val in row: + if isinstance(val, (list, tuple, np.ndarray, pd.Series)): + for x in val: + if x is not None and str(x).strip(): + merged.append(str(x).strip()) + elif pd.notna(val) and str(val).strip(): + val_str = str(val).strip() + for x in val_str.split(';'): + if x.strip(): + merged.append(x.strip()) + return merged + combined = col_df.apply(merge_rows, axis=1) + else: + def first_valid(row: pd.Series) -> str: + """Return the first non-null, non-placeholder string in a row of duplicates.""" + for val in row: + if pd.notna(val) and str(val).strip().lower() not in _NULL_STRINGS: + return str(val).strip() + return "" + combined = col_df.apply(first_valid, axis=1) + + df = df.drop(columns=[col]) + df[col] = combined + + # 5. Enforce columns presence. Ensure all mandatory columns exist. + # Initialize missing columns with empty string or empty list as appropriate. + for col in MANDATORY_COLUMNS: + if col not in df.columns: + if col in MULTIVALUE_COLUMNS: + df[col] = [[] for _ in range(len(df))] + else: + df[col] = "" + + # Set DB column explicitly + db_names_map = { + "web_of_science": "WEB_OF_SCIENCE", + "scopus": "SCOPUS", + "dimensions": "DIMENSIONS", + "lens": "THE_LENS", + "pubmed": "PUBMED", + "cochrane": "COCHRANE" + } + df["DB"] = db_names_map.get(source_db_key, source_db_key.upper()) + + # 6. Apply type contracts & null cleaning + # Scalar columns formatting (strings) + scalar_cols = [col for col in MANDATORY_COLUMNS if col not in MULTIVALUE_COLUMNS and col != 'TC'] + def clean_scalar(x: Any) -> str: + """ + Coerce any cell value into a clean scalar string. + + Containers are joined with ``"; "`` after dropping nulls and + placeholder strings (``"nan"``/``"null"``/``"none"``/``""``); + real ``NaN`` values become ``""``; everything else is + stringified and stripped. + """ + if x is None: + return "" + if isinstance(x, (list, tuple, np.ndarray, pd.Series)): + cleaned_elems = [str(e).strip() for e in x if e is not None and str(e).lower().strip() not in _NULL_STRINGS] + return "; ".join(cleaned_elems) + if pd.isna(x): + return "" + val_str = str(x).strip() + if val_str.lower() in ('nan', 'null', 'none'): + return "" + return val_str + + for col in scalar_cols: + df[col] = df[col].apply(clean_scalar) + + # Standardize Journal Name (SO) - convert to uppercase if not empty + df["SO"] = df["SO"].str.upper() + + # Publication Year (PY): Extract 4-digit format + def clean_year(val: Any) -> str: + """Extract a 4-digit year from arbitrary input; return ``""`` if none is found.""" + if is_null(val): + return "" + if isinstance(val, (list, tuple, np.ndarray, pd.Series)): + val = val[0] if len(val) > 0 else "" + val_str = str(val).strip() + match = re.search(r'\d{4}', val_str) + return match.group(0) if match else "" + df["PY"] = df["PY"].apply(clean_year) + + # Times Cited (TC): Cast to integer and replace nulls with 0 + def clean_tc(val: Any) -> int: + """ + Coerce a citation count to ``int``, defaulting to ``0``. + + Accepts ``"12.0"``-style strings (some sources export the + counter as a float) and unwraps single-element containers. + """ + if is_null(val): + return 0 + if isinstance(val, (list, tuple, np.ndarray, pd.Series)): + val = val[0] if len(val) > 0 else 0 + if str(val).strip().lower() in _NULL_STRINGS: + return 0 + try: + # Handle floats represented as string, e.g. "12.0" + return int(float(str(val).strip())) + except ValueError: + return 0 + df["TC"] = df["TC"].apply(clean_tc) + + # Multi-value columns: split string into list[str], replace nulls with [] + # Custom delimiters by column/source + for col in MULTIVALUE_COLUMNS: + # Detect default delimiter based on source + default_delim = ';' + if source_db_key == "web_of_science" and col == "CR": + default_delim = '\n' # references in WoS txt are separated by newline + elif source_db_key == "web_of_science" and col in ("AU", "AF") and ft == ".bib": + default_delim = ' and ' + elif source_db_key == "scopus" and col in ("AU", "AF") and ft == ".bib": + default_delim = ' and ' + + def convert_to_list(val: Any, delim: str = default_delim) -> List[str]: + """ + Convert a multi-value cell into a clean ``list[str]``. + + If ``val`` is already a container it is flattened and + cleaned in place. Otherwise the string is split first + on ``delim`` (source-specific: ``";"``, ``"\\n"`` or + ``" and "``), and if ``delim`` is absent it falls back + to ``";"``. Empty/null/placeholder tokens are dropped. + """ + if isinstance(val, (list, tuple, np.ndarray, pd.Series)): + # Clean the elements in list + cleaned = [str(x).strip() for x in val if x is not None and str(x).lower().strip() not in _NULL_STRINGS] + return cleaned + if is_null(val): + return [] + val_str = str(val).strip() + if not val_str or val_str.lower() in ('nan', 'null', 'none'): + return [] + + # Semicolon is the standard internal delimiter. If the string contains semicolon, split it. + # If there is another delimiter, we split on it. + parts = [] + if delim in val_str: + parts = val_str.split(delim) + elif ';' in val_str: + parts = val_str.split(';') + else: + parts = [val_str] + + return [p.strip() for p in parts if p.strip()] + + df[col] = df[col].apply(convert_to_list) + + # 7. Keep the full standardized schema. Both AU (surname + initials) + # and AF (full names) belong to the canonical WoS glossary, so we keep + # both columns: dropping one would make downstream functions that read + # the missing field fail with a KeyError. The ``author_format`` argument + # is retained for backward compatibility with existing callers but no + # longer prunes columns from the output schema. + cols_to_keep = [col for col in MANDATORY_COLUMNS if col in df.columns] + df = df[cols_to_keep] + + return df + + def validate(self, df_trans: pd.DataFrame, author_format: str = "surname") -> None: + """ + Phase 3 — defensive schema check on the transformed DataFrame. + + Thin wrapper over :func:`validator.validate_dataframe`. Kept as + a method on the orchestrator so callers can override or + instrument it (e.g. in tests) without monkey-patching the + validator module. + + Args: + df_trans: DataFrame returned by :meth:`transform`. + author_format: Same value as passed to :meth:`transform`; + determines whether ``AU`` or ``AF`` is checked for + presence. + + Raises: + ValueError: On the first schema-contract violation; see + :func:`validator.validate_dataframe` for the exact + rules and message format. + """ + validate_dataframe(df_trans, author_format=author_format) + + def run(self, data_path: str, source_db: str, file_type: str, author_format: str = "surname") -> pd.DataFrame: + """ + Run the file-based ETL: Extract → Transform → Validate. + + This is the entry point used by the Shiny UI when the user + uploads a file. It is *intentionally* tiny — the heavy lifting + lives in the three phase methods so each can be tested in + isolation. + + Args: + data_path: Absolute path to the input file. + source_db: Source database identifier; see :meth:`extract` + for accepted values. + file_type: File extension; see :meth:`extract`. + author_format: ``"surname"`` (default) or ``"fullname"``. + + Returns: + The validated, dashboard-ready DataFrame. + + Raises: + FileNotFoundError: From :meth:`extract` when the path is + missing. + ValueError: From :meth:`extract`, :meth:`transform` or + :meth:`validate` on any contract violation. + """ + df_raw = self.extract(data_path, source_db, file_type) + df_trans = self.transform(df_raw, source_db, file_type, author_format) + self.validate(df_trans, author_format) + return df_trans + + def run_api(self, query: str, source_db: str, max_results: int = 100, author_format: str = "surname") -> pd.DataFrame: + """ + Run the API-based ETL: live query → Transform → Validate. + + Replaces the file-based :meth:`extract` with a call to + :class:`api_retriever.APIRetriever`. Two sources are currently + supported as live queries: OpenAlex (aliased as ``"alex"``) + and PubMed. The query and ``max_results`` are sanitised before + the network call so empty/whitespace queries or non-positive + counts fail fast with a clear :class:`ValueError`. + + Args: + query: Free-text search string. Must contain at least one + non-whitespace character. + source_db: Either ``"openalex"`` / ``"alex"`` or + ``"pubmed"``. + max_results: Cap on the number of records to retrieve. + Coerced to ``int``; must be ``> 0``. Defaults to ``100``. + author_format: ``"surname"`` (default) or ``"fullname"``. + + Returns: + The validated, dashboard-ready DataFrame. + + Raises: + ValueError: If ``query`` is empty, ``max_results`` is not + a positive integer, the source is unsupported, or the + live query returns zero rows. + """ + # Guard: reject empty/whitespace-only queries before hitting the network. + if not isinstance(query, str) or not query.strip(): + raise ValueError("API query cannot be empty. Please enter a search term.") + # Guard: max_results must be a positive integer. + try: + max_results = int(max_results) + except (TypeError, ValueError): + raise ValueError("max_results must be a positive integer.") + if max_results <= 0: + raise ValueError("max_results must be greater than zero.") + + query = query.strip() + source_db_key = source_db.lower().strip() + retriever = APIRetriever() + + if source_db_key in ("openalex", "alex"): + df_raw = retriever.query_openalex(query, max_results=max_results) + file_type = ".json" + source_db_key = "openalex" + elif source_db_key == "pubmed": + df_raw = retriever.query_pubmed(query, max_results=max_results) + file_type = ".txt" + source_db_key = "pubmed" + else: + raise ValueError(f"API extraction not supported for source database: {source_db}") + + if df_raw.empty: + raise ValueError(f"No results found on {source_db} for query: '{query}'") + + df_trans = self.transform(df_raw, source_db_key, file_type, author_format) + self.validate(df_trans, author_format) + return df_trans diff --git a/www/services/format_functions.py b/www/services/format_functions.py index 1a8ee7af4..b28c8a91c 100644 --- a/www/services/format_functions.py +++ b/www/services/format_functions.py @@ -3,6 +3,7 @@ import zipfile import tempfile import os +from .etl_pipeline import BibliometrixETL def format_ab_column(entry, source, file_type): # Function for AB Column (format--> "Abstract") @@ -1519,123 +1520,20 @@ def process_single_file(data, source, file_type, author): Returns: A list of dictionaries containing the formatted data """ - list_bib_data = [] - - if source == "wos": - source = "Web_of_Science" - if file_type.endswith("bib"): - file_type = ".bib" - bib_parser = BibTexParser() - with open(data, 'r', encoding='utf-8') as file: - bib_data = bib_parser.parse_file(file) - json_data = json.dumps(bib_data.entries, indent=4) - list_bib_data = json.loads(json_data) - elif file_type.endswith("txt"): - file_type = ".txt" - bib_data = parse_wos_data(data) - list_bib_data = bib_data - elif file_type.endswith("ciw"): - file_type = ".ciw" - bib_data = parse_wos_data(data) - list_bib_data = bib_data - - elif source == "scopus": - source = "Scopus" - if file_type.endswith("bib"): - file_type = ".bib" - bib_parser = BibTexParser() - with open(data, 'r', encoding='utf-8') as file: - bib_data = bib_parser.parse_file(file) - list_bib_data = bib_data.entries - elif file_type.endswith("csv"): - file_type = ".csv" - bib_data = pd.read_csv(data) - list_bib_data = bib_data.to_dict(orient='records') - - elif source == "dimensions": - source = "Dimensions" - if file_type.endswith("xlsx"): - file_type = ".xlsx" - bib_data = pd.read_excel(data, skiprows=1) - list_bib_data = bib_data.to_dict(orient='records') - elif file_type.endswith("csv"): - file_type = ".csv" - bib_data = pd.read_csv(data, skiprows=1) - list_bib_data = bib_data.to_dict(orient='records') - - elif source == "lens": - source = "The_Lens" - if file_type.endswith("csv"): - file_type = ".csv" - bib_data = pd.read_csv(data) - list_bib_data = bib_data.to_dict(orient='records') - - elif source == "pubmed": - source = "PubMed" - if file_type.endswith("txt"): - file_type = ".txt" - list_bib_data = parse_pubmed_data(data) - - elif source == "cochrane": - source = "Cochrane" - if file_type.endswith("txt"): - file_type = ".txt" - list_bib_data = parse_cochrane_data(data) - - # Extract relevant data and store it in a list of dictionaries - entries = [] - for entry in list_bib_data: - entry_data = { - 'AB': format_ab_column(entry, source, file_type), # Abstract - 'AF': format_af_column(entry, source, file_type), # Authors Full Name - 'AU': format_au_column(entry, source, file_type), # Author/s - 'AU_UN': format_au_un_column(entry, source, file_type), # Authors University - 'AU1_UN': format_au1_un_column(entry, source, file_type), # Authors First University - 'BP': format_bp_column(entry, source, file_type), # Beginning Page - 'EP': format_ep_column(entry, source, file_type), # Ending Page - 'CR': format_cr_column(entry, source, file_type), # Cited References - 'C1': format_c1_column(entry, source, file_type), # Authors Affiliation - 'DB': source, # Database - 'DE': format_de_column(entry, source, file_type), # Author Keywords - 'DI': format_di_column(entry, source, file_type), # DOI - 'DT': format_dt_column(entry, source, file_type), # Document Type - 'EM': format_em_column(entry, source, file_type), # Email - 'FU': format_fu_column(entry, source, file_type), # Funding Details - 'FX': format_fx_column(entry, source, file_type), # Funding Text - 'IS': format_is_column(entry, source, file_type), # Issue - 'JI': format_ji_column(entry, source, file_type), # Abbreviated Journal Name - 'ID': format_id_column(entry, source, file_type), # Index Keywords - 'LA': format_la_column(entry, source, file_type), # Language - 'OA': format_oa_column(entry, source, file_type), # Open Access - 'OI': format_oi_column(entry, source, file_type), # Orcid ID - 'PMID': format_pmid_column(entry, source, file_type), # PubMed ID - 'PU': format_pu_column(entry, source, file_type), # Publisher - 'PY': format_py_column(entry, source, file_type), # Publication Year - 'RP': format_rp_column(entry, source, file_type), # Correspondence Address - 'SC': format_sc_column(entry, source, file_type), # Fields of Research - 'SN': format_sn_column(entry, source, file_type), # ISSN - 'SO': format_so_column(entry, source, file_type), # Journal - 'SR': format_sr_column(entry, source, file_type), # Author, Publication Year, Journal - 'TC': format_tc_column(entry, source, file_type), # Times Cited - 'TI': format_ti_column(entry, source, file_type), # Title - 'UT': format_ut_column(entry, source, file_type), # Publication ID - 'VL': format_vl_column(entry, source, file_type), # Volume - } - - # Add other columns from 'columns' - for column in columns: - if column not in entry_data: # Avoid overwriting existing keys - entry_data[column] = entry.get(column, None) - - # Remove the column based on the value of the 'author' field - if author == "surname": - entry_data.pop('AF', None) # Remove 'AF' if it exists - elif author == "fullname": - entry_data.pop('AU', None) # Remove 'AU' if it exists - - entries.append(entry_data) - - return entries + etl = BibliometrixETL() + # Normalize file extension. + # ``file_type`` may arrive as a full filename ("Scopus.csv"), a bare + # extension ("csv") or a dotted extension (".csv"). Always take the last + # extension via splitext so a filename like "Scopus.csv" yields ".csv" + # rather than ".scopus.csv". + ft = file_type.lower().strip() + ext = os.path.splitext(ft)[1] + if not ext: + # No extension found: file_type was already a bare extension ("csv"). + ext = ft if ft.startswith('.') else '.' + ft + + df = etl.run(data, source, ext, author_format=author) + return df.to_dict(orient='records') def biblio_json(data, source, type, author): diff --git a/www/services/histnetwork.py b/www/services/histnetwork.py index 7848d9744..f55479eb5 100644 --- a/www/services/histnetwork.py +++ b/www/services/histnetwork.py @@ -20,7 +20,12 @@ def histNetwork(df, min_citations=0, sep=";", network=True): - LCS: A list containing the Local Citation Score of each paper. """ M = df.get() - db = M['DB'][0] + # Use positional access: after upstream filtering/sorting the index is not + # guaranteed to start at 0, so label-based M['DB'][0] can raise KeyError. + db = M['DB'].iloc[0] + # Normalize the database tag so the dispatch below is case-insensitive and + # tolerant of the standardized "WEB_OF_SCIENCE"/"SCOPUS" spelling. + db_key = str(db).strip().lower().replace(" ", "_") # Ensure required fields are present if 'DI' not in M: @@ -34,9 +39,9 @@ def histNetwork(df, min_citations=0, sep=";", network=True): # Fill missing values in TC M['TC'] = M['TC'].fillna(0) - if db == "Web_of_Science": + if db_key in ("web_of_science", "isi", "wos"): results = wos(M, min_citations=min_citations, sep=sep, network=network) - elif db == "Scopus": + elif db_key == "scopus": results = scopus(M, min_citations=min_citations, sep=sep, network=network) else: print("\nDatabase not compatible with direct citation analysis\n") @@ -175,6 +180,9 @@ def scopus(M, min_citations=0, sep=";", network=True): # Prepare the M dataframe for the join M_merge = M[['AU', 'PY', 'BP', 'EP', 'SR']].copy() M_merge['AU'] = M_merge['SR'].str.extract(r'^(.*?),').apply(lambda x: x.str.replace('.', '').str.strip()) + # CR['PY'] is extracted as float above; the standardized M stores PY as a + # string, so coerce here to keep the merge keys on a matching dtype. + M_merge['PY'] = pd.to_numeric(M_merge['PY'], errors='coerce') M_merge['BP'] = pd.to_numeric(M_merge['BP'], errors='coerce') M_merge['EP'] = pd.to_numeric(M_merge['EP'], errors='coerce') M_merge['PP'] = M_merge.apply(lambda row: f"{row['BP']}-{row['EP']}" if pd.notna(row['BP']) else np.nan, axis=1) @@ -189,7 +197,10 @@ def scopus(M, min_citations=0, sep=";", network=True): # Calculate the Local Citation Score (LCS) LCS = CR.groupby('SR_cited').size().reset_index(name='LCS') - # Merge LCS scores with M + # Merge LCS scores with M. Reset the index first: upstream processing can + # leave 'SR' as a named index level, which makes merging on the 'SR' column + # ambiguous ("'SR' is both an index level and a column label"). + M = M.reset_index(drop=True) M = M.merge(LCS, left_on='SR', right_on='SR_cited', how='left').fillna({'LCS': 0}) print(f"\nCalculated Local Citation Scores (LCS) for {len(M)} papers...\n") diff --git a/www/services/parsers.py b/www/services/parsers.py index 72b9d370e..7fa8ef8cb 100644 --- a/www/services/parsers.py +++ b/www/services/parsers.py @@ -1,8 +1,50 @@ +""" +Plain-text parsers for legacy bibliographic export formats. + +Each function here converts an on-disk export from one of three sources +— Web of Science (``.txt``/``.ciw``), PubMed MEDLINE (``.txt``), or +Cochrane Library (``.txt``) — into a Python ``list[dict]`` whose keys +are the two-letter (or short) field codes used by the originating +system. The dict is then fed to the ETL pipeline (see +:mod:`etl_pipeline`) for normalisation into the canonical WoS schema. + +Each format follows roughly the same grammar: + +- A record is a block of lines. +- Records are separated by a delimiter (blank line, ``ER`` marker, or + ``Record #`` header). +- A field line starts with a key prefix (e.g. ``AU - Smith J``); + continuation lines belong to the previous key. +""" + +from typing import List, Dict, Any + from .utils import * #### WEB OF SCIENCE PARSER #### -def parse_wos_data(datapath): # PARSER FOR WEB OF SCIENCE TXT and CIW +def parse_wos_data(datapath: str) -> List[Dict[str, Any]]: + """ + Parse a Web of Science ``.txt`` / ``.ciw`` export into a list of records. + + The WoS plain-text format uses two-letter field codes (``AU``, ``TI``, + ``SO``, …) on lines that begin in column 0; continuation lines are + indented with two spaces and append to the previous key. + + A handful of fields (``DE``, ``C3``, ``EM``, ``FU``, ``FX``, ``WC``) + are special-cased: their continuation lines are space-joined into a + single string instead of accumulated as a list, because downstream + code expects a flat string for those columns. + + Args: + datapath: Absolute path to the WoS export file. The file is read + assuming UTF-8 encoding. + + Returns: + A list where each item is a dict ``{field_code: [value, ...]}`` + for one bibliographic record. The two header lines of the WoS + file are intentionally skipped. + """ elem_data = [] data = {} current_key = None @@ -40,7 +82,26 @@ def parse_wos_data(datapath): # PARSER FOR WEB OF SCIENCE TXT and CIW #### PUBMED PARSER #### -def parse_pubmed_data(datapath): # PARSER FOR PUBMED TXT +def parse_pubmed_data(datapath: str) -> List[Dict[str, str]]: + """ + Parse a PubMed MEDLINE ``.txt`` export into a list of records. + + The MEDLINE format uses ``KEY - value`` lines where ``KEY`` is a + two-to-four letter code (e.g. ``PMID``, ``AU``, ``TI``, ``AB``). + Lines without that prefix are treated as continuations of the + previous key. + + When the same key appears multiple times in a record (typical for + ``AU`` with many authors) the values are joined with ``;`` into a + single string; the ETL pipeline later splits them back into a list. + + Args: + datapath: Absolute path to the MEDLINE export file. The file is + read assuming UTF-8 encoding. + + Returns: + A list of dicts ``{key: value_string}``, one per record. + """ data = [] current_record = {} @@ -77,7 +138,29 @@ def parse_pubmed_data(datapath): # PARSER FOR PUBMED TXT #### COCHRANE PARSER #### -def parse_cochrane_data(datapath): +def parse_cochrane_data(datapath: str) -> List[Dict[str, str]]: + """ + Parse a Cochrane Library plain-text export into a list of records. + + Cochrane records are delimited by a ``Record #N`` header and use + ``KEY: value`` lines (note the colon, in contrast to WoS/MEDLINE). + Lines without that pattern are treated as continuations of the + previous key. + + Two post-processing steps are applied per record: + + - The synthetic ``Record`` field (just a counter) is dropped. + - If the abstract starts with ``"Abstract - Background"``, the + first 22 characters are stripped so the abstract starts at the + actual prose. + + Args: + datapath: Absolute path to the Cochrane export file. The file + is read assuming UTF-8 encoding. + + Returns: + A list of dicts ``{key: value_string}``, one per record. + """ data = [] current_record = {} diff --git a/www/services/utils.py b/www/services/utils.py index b2a4b1fe2..c0b385288 100644 --- a/www/services/utils.py +++ b/www/services/utils.py @@ -1,3 +1,21 @@ +""" +Shared utilities and constants for the Bibliometrix dashboard. + +This module is a *grab-bag* used by virtually every other module in +:mod:`www.services`. It is intentionally heavy on imports because +re-importing them in each dependant module would slow application +startup. Its actual public surface is small: + +- :data:`columns` — the canonical column order for the WoS-style + DataFrame consumed by the dashboard. +- :data:`ICONS` — a registry of pre-built FontAwesome icon objects, + centralised here so the rest of the UI can refer to icons by short + semantic keys (``"home"``, ``"filters"``, …) instead of repeating the + literal FA names. +- :func:`empty_plot` — a Plotly placeholder used while waiting for the + user to click *Run*. +""" + import os import io import re @@ -17,7 +35,10 @@ import igraph as ig import faicons as fa import networkx as nx -import geopandas as gpd +try: + import geopandas as gpd +except ImportError: + gpd = None import plotly.express as px import matplotlib.pyplot as plt import plotly.graph_objects as go @@ -68,7 +89,63 @@ from networkx.algorithms.community import greedy_modularity_communities -columns = ['AB', 'AF', 'AU', 'AU1_UN', 'AU_UN', 'BP', 'C1', 'CR', 'DB', 'DE', +def _ensure_nltk_resources(): + """ + Make sure the NLTK corpora used by the text-analysis tabs are present. + + The term-extraction code (Most Frequent Words, Word Cloud, Tree Map, Word + Frequency, Trend Topics, Thematic Map/Evolution) relies on ``stopwords`` + and ``wordnet``. These are data files that ``pip install nltk`` does NOT + download, so on a fresh environment those tabs would crash with + ``LookupError: Resource 'stopwords' not found``. + + This bootstrap downloads any missing resource once, quietly, at import + time. It is a no-op when the corpora are already cached, and it fails + softly (a warning, never a crash) if the machine is offline — the affected + tabs simply behave as before until the data is available. + """ + import nltk + + resources = { + "corpora/stopwords": "stopwords", + "corpora/wordnet": "wordnet", + "corpora/omw-1.4": "omw-1.4", + "tokenizers/punkt": "punkt", + } + import os + import zipfile + + for path, pkg in resources.items(): + try: + nltk.data.find(path) + continue + except LookupError: + pass + try: + nltk.download(pkg, quiet=True) + # Some environments leave the resource as a downloaded ".zip" that + # nltk.data.find cannot see. Unzip it in place if needed. + try: + nltk.data.find(path) + except LookupError: + category = path.split("/")[0] # e.g. "corpora" / "tokenizers" + for base in nltk.data.path: + zip_path = os.path.join(base, category, pkg + ".zip") + if os.path.exists(zip_path): + with zipfile.ZipFile(zip_path) as zf: + zf.extractall(os.path.join(base, category)) + break + except Exception as exc: # offline / network error: don't block startup + import warnings + warnings.warn(f"Could not download NLTK resource '{pkg}': {exc}") + + +# Download NLTK data the first time the package is imported, so the text-mining +# tabs work out of the box on any machine without a manual setup step. +_ensure_nltk_resources() + + +columns = ['AB', 'AF', 'AU', 'AU1_UN', 'AU_UN', 'BP', 'C1', 'CR', 'DB', 'DE', 'DI', 'DT', 'EM', 'EP', 'FU', 'FX', 'ID', 'IS', 'JI', 'LA', 'OA', 'OI', 'PMID', 'PU', 'PY', 'RP', 'SC', 'SN', 'SO', 'SR', 'TC', 'TI', 'UT', 'VL'] @@ -150,15 +227,22 @@ } -def empty_plot(message="Click RUN to generate analysis"): +def empty_plot(message: str = "Click RUN to generate analysis") -> "go.Figure": """ - Create an empty plotly figure with a message for placeholder display. - + Create an empty Plotly figure that displays a centred message. + + The figure is used as a placeholder inside every analysis tab while + the dashboard waits for the user to load data and press *Run*. The + axes are hidden, the background is transparent, and the message is + centred so the placeholder blends with the surrounding card layout. + Args: - message (str): Message to display in the empty plot - + message: Text rendered at the centre of the empty plot. + Defaults to a Run hint. + Returns: - plotly.graph_objects.Figure: Empty figure with message + A :class:`plotly.graph_objects.Figure` with no traces, hidden + axes, and a single centred annotation. """ fig = go.Figure() @@ -197,5 +281,48 @@ def empty_plot(message="Click RUN to generate analysis"): height=400, autosize=True ) - - return fig \ No newline at end of file + + return fig + + +def normalize_dashboard_types(df: "pd.DataFrame") -> "pd.DataFrame": + """ + Coerce contract-numeric columns to numeric dtypes at the dashboard boundary. + + The source-agnostic ETL emits ``PY`` (publication year) as a 4-digit + *string* and the dashboard rebuilds its working DataFrame via + :func:`pandas.read_json` / :func:`pandas.read_excel`. When some records + have a missing year (common for Scopus, PubMed, Dimensions, …) the empty + string poisons pandas' automatic numeric inference, so the whole ``PY`` + column stays ``object``/``str``. Every analysis function that does year + arithmetic (``Min_Year``/``Max_Year``, CAGR, *Average citations per year*, + the *Filters* tab, *Most cited documents*, …) then fails with + ``unsupported operand type(s) for -: 'str' and 'str'``. + + This helper is applied once, the moment any DataFrame enters the + dashboard's reactive store, so every downstream tab sees the same numeric + contract regardless of the original database: + + - ``PY`` → nullable ``Int64`` (years stay integers; missing years become + ```` instead of a year-breaking ``0``, and arithmetic / ``min`` / + ``max`` / ``groupby`` all skip them). + - ``TC`` → numeric (citation counts), with missing values imputed to ``0``. + + Absent columns are ignored, so non-WoS schemas and the sample/Excel inputs + are handled safely. + + Args: + df: The DataFrame just loaded into the dashboard (from JSON, Excel or + the live API path). + + Returns: + The same DataFrame with ``PY``/``TC`` normalised. The input is mutated + in place and also returned for convenient chaining. + """ + if df is None or not isinstance(df, pd.DataFrame) or df.empty: + return df + if "PY" in df.columns: + df["PY"] = pd.to_numeric(df["PY"], errors="coerce").astype("Int64") + if "TC" in df.columns: + df["TC"] = pd.to_numeric(df["TC"], errors="coerce").fillna(0) + return df \ No newline at end of file diff --git a/www/services/validator.py b/www/services/validator.py new file mode 100644 index 000000000..3c4b85775 --- /dev/null +++ b/www/services/validator.py @@ -0,0 +1,135 @@ +""" +Schema validator for the Bibliometrix ETL pipeline. + +Ensures that the DataFrame produced by the ETL conforms to the canonical +Web of Science (WoS) schema required by the dashboard: + +- All mandatory columns are present. +- No NaN/None values remain (the ETL must impute or drop them upstream). +- Multi-value columns (AU, AF, C1, CR, DE, ID) are ``list[str]``. +- Scalar columns are ``str`` (or numeric for TC). + +This module is invoked at the end of every ETL run as a defensive contract: +if validation fails, downstream visualisation code is guaranteed not to see +malformed data. +""" + +import logging +import pandas as pd +import numpy as np +from typing import List, Any + +logger = logging.getLogger(__name__) + +# Define the standard columns from the glossary +MANDATORY_COLUMNS: List[str] = [ + 'DB', 'UT', 'DI', 'PMID', 'TI', 'SO', 'JI', 'PY', 'DT', 'LA', 'TC', + 'AU', 'AF', 'C1', 'RP', 'CR', 'DE', 'ID', 'AB', 'VL', 'IS', 'BP', 'EP', 'SR' +] + +# Columns that MUST be list of strings in the final DataFrame +MULTIVALUE_COLUMNS: List[str] = ['AU', 'AF', 'C1', 'CR', 'DE', 'ID'] + +def validate_dataframe(df: pd.DataFrame, author_format: str = "surname") -> None: + """ + Validate that ``df`` conforms to the standardised WoS schema. + + The check is split into three contracts: + + 1. **Column presence** — every mandatory column from + :data:`MANDATORY_COLUMNS` must exist. ``AU`` or ``AF`` is excluded + depending on ``author_format``. + 2. **Null absence** — no column may contain NaN/None. The ETL is + responsible for imputing missing values (typically with ``""`` for + strings, ``0`` for TC, ``[]`` for multi-value columns). + 3. **Type contract** — multi-value columns must be lists of + strings; scalar columns must be strings (except ``TC`` which is + numeric: ``int``, ``float``, ``np.integer`` or ``np.floating``; + booleans are explicitly rejected). + + Args: + df: DataFrame produced by the ETL pipeline. + author_format: Either ``"surname"`` (keep ``AU``, drop ``AF``) + or ``"fullname"`` (keep ``AF``, drop ``AU``). Defaults to + ``"surname"``. + + Raises: + ValueError: With a descriptive message on the first contract + violation. The function is fail-fast: it does not aggregate + errors across columns. + + Returns: + None. On success a confirmation message is printed to stdout. + """ + # 1. Verify that all mandatory columns exist. + # Both AU and AF are part of the canonical WoS glossary and are always + # required. The ``author_format`` argument is kept for backward + # compatibility with existing callers but no longer relaxes the contract. + expected_cols = [col for col in MANDATORY_COLUMNS] + + missing_cols = [col for col in expected_cols if col not in df.columns] + if missing_cols: + raise ValueError(f"Validation failed: Missing mandatory columns: {missing_cols}") + + # 2. Assert no NaN or None values remain in the DataFrame + # Note: df.isna() checks for both NaN and None. + for col in df.columns: + null_count = df[col].isna().sum() + if null_count > 0: + raise ValueError(f"Validation failed: Column '{col}' contains {null_count} null/NaN values.") + + # 3. Assert type contracts: + # Multi-value columns must be lists of strings. + # Non-multi-value columns must be strings or ints. + for col in df.columns: + if col in MULTIVALUE_COLUMNS: + # Check if all elements in the column are lists (and not strings or numbers) + non_list_mask = df[col].apply(lambda x: not isinstance(x, list)) + non_list_count = non_list_mask.sum() + if non_list_count > 0: + sample_indices = df[non_list_mask].index[:3].tolist() + raise ValueError( + f"Validation failed: Column '{col}' must contain only lists, " + f"but has {non_list_count} non-list elements (e.g. at indices {sample_indices})." + ) + + # Check if lists contain only strings + def check_list_elements(lst: Any) -> bool: + """Return True if ``lst`` is a list whose elements are all strings.""" + if not isinstance(lst, list): + return False + return all(isinstance(x, str) for x in lst) + + invalid_elements_mask = df[col].apply(lambda x: not check_list_elements(x)) + invalid_elements_count = invalid_elements_mask.sum() + if invalid_elements_count > 0: + raise ValueError( + f"Validation failed: List elements in column '{col}' must be strings, " + f"but found invalid elements at {invalid_elements_count} rows." + ) + else: + # Non-multivalue columns must be scalar (str or int) + if col == 'TC': + # Check for integer/numeric type. Pandas/NumPy can store TC as + # np.int64/np.float64 (from read_csv/read_excel), so we accept + # any numeric type but reject booleans (bool is a subclass of int). + def _is_numeric(x: Any) -> bool: + """Return True for any numeric scalar (int/float/numpy) except booleans.""" + if isinstance(x, bool): + return False + return isinstance(x, (int, float, np.integer, np.floating)) + non_int_mask = df[col].apply(lambda x: not _is_numeric(x)) + if non_int_mask.any(): + raise ValueError(f"Validation failed: Column 'TC' must contain numeric values.") + else: + # String columns + non_str_mask = df[col].apply(lambda x: not isinstance(x, str)) + if non_str_mask.any(): + non_str_count = non_str_mask.sum() + sample_vals = df[non_str_mask][col].head(3).tolist() + raise ValueError( + f"Validation failed: Column '{col}' must contain only strings, " + f"but has {non_str_count} non-string elements (sample values: {sample_vals})." + ) + + logger.info("Validation passed: DataFrame conforms to the standardized WoS schema.")