Protein-protein interaction annotation should always be placed in the "physical interaction" section. However, due to the limitation that only WT to WT interactions can be described, a previous curator developed an alternative approach. This involves using PHIPO terms, such as "PHIPO:0001107 absence of pathogen–host protein–protein interaction", within the "Pathogen–host interaction phenotype" section.
Nevertheless, it would be preferable to include these annotations in the physical interaction section to ensure consistency.
example: https://canto.phi-base.org/curs/7f79fa45d157bd97
It would also be worthwhile to establish a similar setup for a new section called "Molecular function/enzyme activity". For instance, in the same entry, "PHIPO:0001195 inhibition of pathogen chorismate mutase by host present" has been added in the "Pathogen–host interaction phenotype" section. This should go into the new "Molecular function/enzyme activity" section.
Protein-protein interaction annotation should always be placed in the "physical interaction" section. However, due to the limitation that only WT to WT interactions can be described, a previous curator developed an alternative approach. This involves using PHIPO terms, such as "PHIPO:0001107 absence of pathogen–host protein–protein interaction", within the "Pathogen–host interaction phenotype" section.
Nevertheless, it would be preferable to include these annotations in the physical interaction section to ensure consistency.
example: https://canto.phi-base.org/curs/7f79fa45d157bd97
It would also be worthwhile to establish a similar setup for a new section called "Molecular function/enzyme activity". For instance, in the same entry, "PHIPO:0001195 inhibition of pathogen chorismate mutase by host present" has been added in the "Pathogen–host interaction phenotype" section. This should go into the new "Molecular function/enzyme activity" section.