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---
abstract: "This work investigates descriptive captions as an additional source of supervision
for biological multimodal foundation models. Images and captions can be viewed
as complementary samples from the latent morphospace of a species, each capturing
certain biological traits. Incorporating captions during training encourages
alignment with this shared latent structure, emphasizing potentially diagnostic
characters while suppressing spurious correlations. The main challenge, however,
lies in obtaining faithful, instance-specific captions at scale. This requirement
has limited the utilization of natural language supervision in organismal biology
compared with many other scientific domains. We complement this gap by
generating synthetic captions with multimodal large language models (MLLMs),
guided by Wikipedia-derived visual information and taxon-tailored format examples.
These domain-specific contexts help reduce hallucination and yield accurate,
instance-based descriptive captions. Using these captions, we train BioCAP (i.e.,
BioCLIP with Captions), a biological foundation model that captures rich semantics
and achieves strong performance in species classification and text-image
retrieval. These results demonstrate the value of descriptive captions beyond labels
in bridging biological images with multimodal foundation models."
authors:
- family-names: Zhang
given-names: Ziheng
- family-names: Ma
given-names: Xinyue
- family-names: Campolongo
given-names: "Elizabeth G."
- family-names: Thompson
given-names: "Matthew J."
- family-names: Zhang
given-names: Net
- family-names: Gu
given-names: Jianyang
cff-version: 1.2.0
date-released: "2025-10-24"
identifiers:
- doi: "10.5281/zenodo.17437591"
- description: "The GitHub release URL of tag v1.0.0."
type: url
value: "https://github.com/Imageomics/biocap/releases/tag/v1.0.0"
- description: "The GitHub URL of the commit tagged with v1.0.0."
type: url
value: "https://github.com/Imageomics/biocap/tree/32ddb13fc60a80273ae3cf1ddce72113f0cd0f14"
keywords:
- clip
- biology
- CV
- imageomics
- animals
- plants
- fungi
- species
- images
- taxonomy
- "rare species"
- "endangered species"
- "evolutionary biology"
- multimodal
- "knowledge-guided"
- "synthetic captions"
- "caption-generation"
license: MIT
message: "If you use this software, please cite both the article and the software itself."
repository-code: "https://github.com/Imageomics/biocap"
title: "BioCAP"
version: 1.0.0
type: software
references:
- authors:
- family-names: Gu
given-names: Jianyang
- family-names: Stevens
given-names: Samuel
- family-names: Campolongo
given-names: "Elizabeth G."
- family-names: Thompson
given-names: "Matthew J."
- family-names: Zhang
given-names: Net
- family-names: Wu
given-names: Jiaman
- family-names: Mai
given-names: Zheda
cff-version: 1.2.0
date-released: "2025-09-03"
doi: "10.5281/zenodo.15644363"
license: MIT
repository-code: "https://github.com/Imageomics/bioclip-2"
title: "BioCLIP 2"
version: 1.0.1
type: software
- authors:
- family-names: Stevens
given-names: Samuel
- family-names: Wu
given-names: Jiaman
- family-names: Thompson
given-names: "Matthew J."
- family-names: Campolongo
given-names: "Elizabeth G."
- family-names: Song
given-names: "Chan Hee"
- family-names: Carlyn
given-names: "David Edward"
date-released: "2024-09-19"
doi: "10.5281/zenodo.10895870"
license: MIT
repository-code: "https://github.com/Imageomics/bioclip"
title: BioCLIP
version: 1.0.2
type: software
- authors:
- family-names: Stevens
given-names: Samuel
- family-names: Wu
given-names: Jiaman
- family-names: Thompson
given-names: "Matthew J."
- family-names: Campolongo
given-names: "Elizabeth G."
- family-names: Song
given-names: "Chan Hee"
- family-names: Carlyn
given-names: "David Edward"
- family-names: Dong
given-names: Li
- family-names: Dahdul
given-names: "Wasila M"
- family-names: Stewart
given-names: Charles
- family-names: "Berger-Wolf"
given-names: Tanya
- family-names: Chao
given-names: "Wei-Lun"
- family-names: Su
given-names: Yu
title: "BioCLIP: A Vision Foundation Model for the Tree of Life"
year: 2024
pages: "19412-19424"
collection-title: "Proceedings of IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)"
type: coference-paper
- authors:
- family-names: Ilharco
given-names: Gabriel
- family-names: Wortsman
given-names: Mitchell
- family-names: Wightman
given-names: Ross
- family-names: Gordon
given-names: Cade
- family-names: Carlini
given-names: Nicholas
- family-names: Taori
given-names: Rohan
- family-names: Dave
given-names: Achal
- family-names: Shankar
given-names: Vaishaal
- family-names: Namkoong
given-names: Hongseok
- family-names: Miller
given-names: John
- family-names: Hajishirzi
given-names: Hannaneh
- family-names: Farhadi
given-names: Ali
- family-names: Schmidt
given-names: Ludwig
title: OpenCLIP
version: v0.1
type: software
doi: "10.5281/zenodo.5143773"
date-released: "2021-07-28"